LOCUS       DACTZW010000001       130288 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.001, whole genome shotgun sequence.
ACCESSION   DACTZW010000001 DACTZW010000000
VERSION     DACTZW010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 130288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 130288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..130288
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.001"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            477..1370
                     /locus_tag="JAM15_00005"
     CDS             477..1370
                     /locus_tag="JAM15_00005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003373580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfide/dihydroorotate dehydrogenase-like
                     FAD/NAD-binding protein"
                     /protein_id="HAT6796652.1"
                     /translation="MSNKIVSKRQLTDSIYLMEIEAPRVAKSSQPGQFIIIKNDEKGE
                     RIPLTIADYDREKGTVTIVFQTVGASTKKLAMFEENDFVMDFVGPLGQASEFIHEDIE
                     ELRNKKILFVAGGVGSAPVYPQVKWFKEHGLDVDVIIGARTKELIILEDDMKKVAKNV
                     YVSTDDGTYGFNGRVTDLLKDLVDNQGKKYDQAIVIGPMIMMKFMCQLTKELNIPTIV
                     SLNTIMIDGTGMCGGCRVSVGNETKFACVDGPEFDGHLVDFDQAMRRQSMYKTQEGRA
                     ILKLEEGDSHHHSNCGCGGNK"
     gene            1370..2764
                     /gene="gltA"
                     /locus_tag="JAM15_00010"
     CDS             1370..2764
                     /gene="gltA"
                     /locus_tag="JAM15_00010"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent glutamate synthase"
                     /protein_id="HAT6796653.1"
                     /translation="MDAKKVKVPVREQEPAVRATNFDEVCLGYNKEEAMAEANRCLAC
                     KKPKCVGGCPVGIDIPGFITKIKEDDIEGAAKVIAKSSSLPAVCGRVCPQESQCEGVC
                     ILGIKSDAVSIGKLERFVADWSKENDINLSDTEPKKNQKVAVIGSGPAGLACAGDLAK
                     KGYDVTIFEAMHEPGGVLTYGIPEFRLPKQAVVQPEIDNIRKLGVKIETNVIVGKTIT
                     VDELIEDEGFEAIFIGSGAGLPMFMNIPGENANGVFSANEFLTRVNLMKAYRDDYDTP
                     ISSGKKVAVVGGGNVAMDAARTALRLGSESYIVYRRSEKELPARAEEVHHAKEEGIIF
                     NTLTNPKEILVDENGYVKGMVCIRMELGEPDDSGRRRPIEIEGSEFVLDVDTVIMSLG
                     TSPNPLISSTTKSLNINKKRCLITDENGQTSKEGVFAGGDAVTGAATVISAMGAGKTA
                     AASIDEYLKAKVNA"
     gene            3130..5349
                     /locus_tag="JAM15_00015"
     CDS             3130..5349
                     /locus_tag="JAM15_00015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HAT6796654.1"
                     /translation="MKKREKVFDGLVFKHILILLILLVLIDLTSTIIYASNSMEITSR
                     NMIEASKRELENYLEVNISLLKALSQDDRFSNGETSLIEKGKLLRPYQKEYNLFMIGI
                     TDTKGNASSTYRENVNSIKDKPSFEKAIKTKQVVVSDIEVSNVTGEKVFIIYVPIVKN
                     NEMIGTIFASFYFQDVNNLISRSNFDDSIKFLMIDKDYTIISHPNKKYVNDKSKMLDL
                     EGNIIGTTKSEILKNINKKCQGNFLSWDNWRLYNVKYTNIKWTNWTLVSKCNIFKNFK
                     NLIVNFMIKLYFYIVIFMILWKLSNAKLIEQLKKLAYYDSLSGIKNKEKFRKDSMYIL
                     KNYYQDNFYLVQLDVNKFKYINEMFGYAEGNKILIHISQVLNNNTNKYEICARMDNDH
                     FILLIACNTEDELLNRLSKINKEICNLNTTNSSKYKIVMSSGIYKITKKDDIKKIDLL
                     IDRANIAAKSKKEKYEHSYSFFNEDTRNRLYKEKRLEDNMNKALEKGEFIVYYQPKYS
                     LDDVNEIEGAEALIRWNSPEFGFISPIDFVPLFEKNGFIVNIDMFVFEEVCKTLNKWI
                     NKGYTPVPISVNMSRVHLYRDNFIENITDLISKYNISPEFIELELTESVVFDNLNILI
                     DIMKKIKEIGFLISMDDFGSGYSSLNLLKDLSFDILKLDRGFLIETTDTKRGKIIISK
                     IVEMAKAIDIKVICEGVETYEQVEFLKEIGCDKVQGYLFAKPMVLDEFEKHLNFKFD"
     gene            5496..6242
                     /locus_tag="JAM15_00020"
     CDS             5496..6242
                     /locus_tag="JAM15_00020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6796655.1"
                     /translation="MNILSIRNISKTYCRNIPFKALDKVSLNIEKGEFVSVMGPSGSG
                     KSTLLNIISTVDRQSEGEVILDGYDVSKLEGEKLAEFRRKQLGFVFQDFNLVDTLTVG
                     ENIMLPLTLDGASIKDMNIQTKSISKFLGIDKILDRKTYEISGGQAQRCAIARAIINK
                     PAILLADEPTGNLDSKSTDDVLKLFTRINKEQNVTTLMVTHEAYSASYSDRVIFIKDG
                     CIYTEIKKSESSNSFYSDILAVLSQIGGVR"
     gene            6242..8122
                     /locus_tag="JAM15_00025"
     CDS             6242..8122
                     /locus_tag="JAM15_00025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6796656.1"
                     /translation="MDFRKFAYNNIVRNFRAYLAYFLSSVFSIMIFFVFAVSMFHPII
                     TKSGMQSGSTAFMALMTSELIILGFSLLFILYSLGNFLKYRLKDFGVLMIIGMSNKQL
                     KKLILIENLIIGFLAVMLGILLGLSISKLFLLYLSKLFYMNLTEFYFPVKAILLTIVS
                     FMILFLITGPMSLKLLSKKSILELLVGTKKPKKEIKSSKLFGIIGAVCLILGYAMIIF
                     GNKLKINGGMYTTALLITLGIFLFFSQFTILILKYLKNKEKFYKNKVNMLLISNLIYK
                     LKDNTRLLFLITILLSATLVAFTTTSTLVSSQGESSKNNFPMVYSYFSEHNNEKEYEE
                     LQQIREAIKGYDYKELSFPVLKYNREVLLSVKSYNKLSKELGLDKISSKLERYEGIII
                     PSSISQEHINSLKQLKNLNIKNLNIEVKKSKNKIIFPTGLFSKIVVISDDLYDEVKGE
                     FSKINFHGFDYKNWQSSAKITENLKEKHFNLDREYNRSYFLTLPDMYLVELQQSKILQ
                     FMGVFIGVILFIAVFSFLYFRLYTDEIEDNVKYKKLSKIGLSFKNMNKIVSIEIGTLF
                     FIPYFIAIINSIISLLFLNQVLNNSFKLENLGILLLISSIYSLYFYLLKKIYTRKVWF
                     FD"
     gene            8241..9632
                     /locus_tag="JAM15_00030"
     CDS             8241..9632
                     /locus_tag="JAM15_00030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HAT6796657.1"
                     /translation="MENQQLLGTERISKLLLKYSIPAIIGMLVNSLYNVVDRIFIGNI
                     PGVGPLAITGLGVTMPIMTIILAFGMLIGIGTTTTISIKLGQGKVEEARKLIGNAMTL
                     SVITGIIIMILGILFANKILTLFGASENTLIYAKSYINIILLGTVVNLLSFSLNHSIR
                     ADGSPKISAGIMIVGCLTNIVLDWILIFGFNLGIQGAAIATVTSQALTAILTIGYYIS
                     GKSNLRFSKSNLKLDKKLIKAVFAIGMSPFAMQLAASLVQVISNIALKTHGGDLAIGA
                     MATISSIAMVFLMPIFGINQGAQPIIGFNYGAEKYDRVKKAYLGSLVVATIILCMGMV
                     VVMLFPEAIIGIFNKDPELMNISVNGLRIYLLMLPIVGLSVTGTNFIQSIGKAKMAML
                     LSLLRQVILLIPAVLILPTFLGLQGVWTAQPVSDFIATVITGIVVFRELKRYTPKTEK
                     LNENERLNEITTE"
     gene            9739..10779
                     /locus_tag="JAM15_00035"
     CDS             9739..10779
                     /locus_tag="JAM15_00035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein Fic"
                     /protein_id="HAT6796658.1"
                     /translation="MEFTKKSKLKNMYVNMNVARMLSKINEYKGRQLLYKKQPKEILE
                     NLEKKSLVDCSESTYIGNQRDSSNFNLEKLISNEVTPRSREELSIVEYRDVVKTINSA
                     YESIPISSQTILELHGYLYKFSSTRGGSYKSDNDFIEHNLKPSEFISIDSSVNKVEKA
                     VEEICEAYNTLIEEDEIDILILISAFVLDFILIHPFKEGNIKMARVLILLLLNKNGYE
                     VGRYISLGKIFDDSSYEYYSNLNYLKASIGSEKADMNAWIEYFLETILTAYEKLDDSL
                     NISDKKRQTKTSRIEKIINSTLGYFTKEDIRDLCPDIPEPTINRVFNNLRKQDKIEVV
                     ARGRSAKWKKKY"
     gene            11268..11921
                     /locus_tag="JAM15_00040"
     CDS             11268..11921
                     /locus_tag="JAM15_00040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HAT6796659.1"
                     /translation="MKKKLLYINVNSKPEDLSSSKTVARKFINKFMEKNKDFEVEEID
                     LYKEHIPRLEYQYFEKRNSIVSEENAKNLDDKDRKELTKIRNLCDQFVSASVYVIAAP
                     MWSLSFPAPLKEYIDCIIQDGKTISFEGNDKPQGILNDIDRSMVYIQSSGGHIPWVLK
                     PVMNKGLNYVESIMKFIGIKKFDELLVDGTGTSEEERQAAIEKASEKIDGIIDGMKF"
     gene            11997..12206
                     /locus_tag="JAM15_00045"
     CDS             11997..12206
                     /locus_tag="JAM15_00045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796660.1"
                     /translation="MREEKSNEKYDCYWCNQENNFCVEIKDNIVMIDDGTGTLKQAVF
                     IGYKQIQINLNCSHCQNLNRIKLNL"
     gene            complement(12346..12909)
                     /locus_tag="JAM15_00050"
     CDS             complement(12346..12909)
                     /locus_tag="JAM15_00050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HAT6796661.1"
                     /translation="MNNELNTIILETLNNADITSNDIPSIDLYMDQIISLIDNKLSPN
                     KRFESDKILTKTMINNYSKEGLIKPVKGKKYTKEQILQMIIIYSMKNTLTIQEIKRIL
                     HGVYEKDNFSEKDLVSCYEKFMLIKENQRKNIPDFIESNFENISINPENKDDLLIALL
                     SLTSMADQLKNISEKLVDRYFPDITKK"
     gene            13073..13726
                     /locus_tag="JAM15_00055"
     CDS             13073..13726
                     /locus_tag="JAM15_00055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HAT6796662.1"
                     /translation="MYQFFLKGRDPISSLTHFIGACLSLLATIILVFQSVTLQETSLL
                     MIVSVSVFGLSLIALYSASSYYHFLKGTPEQELFFRKVDHAMIYVLIAGSYTPICLNF
                     MEKKEGIIFVTAIWIVAFIGIIIKIFWMDAPRWLSTSIYLLMGWAIVFDINAFNSIPK
                     DCLRLLIMEGVSYSIGAIIYIIKKPNISPEFGFHEIFHIFIMIGSLFHFLAVLLYVL"
     gene            14588..15532
                     /locus_tag="JAM15_00060"
     CDS             14588..15532
                     /locus_tag="JAM15_00060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase regulatory
                     subunit"
                     /protein_id="HAT6796663.1"
                     /translation="MKFLRIEDEVIYSKKRYKLKREIDKLFLDEEYFQIEPQLFEEYD
                     EFTTINNKIPEESMVKVVNGKVMVLRADITTSIIKSLVPRWEDGLKLKLFYNSSIYKN
                     KNTVGIKEIRQIGCEYLGEASVEADREVVKLALKILEKYNNNFILEVGSSKYIHGLLE
                     ELNLNKNCENQIKNLLYTKNTHELKVYIEELKIKREVKELLSNILSLQGNLYNVIEKS
                     NKFYCNNKMKQALEELKQVNNLIEECNFLDKARFDLSMITMLDYYEGIMFRGYYPNSY
                     KEILSGGRYDSLTKEYGKEIPAIGFTLSVDELMKYVYK"
     gene            15554..16180
                     /locus_tag="JAM15_00065"
     CDS             15554..16180
                     /locus_tag="JAM15_00065"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HAT6796664.1"
                     /translation="MDYLTIALAKGRIEGESFKKFKKMGLGDSIDTDTRKLIFKDEEN
                     KIIYIHVKPSDVVTYVEKGVADLGIAGKDTILENETDVYEIYDLGFGKCKFAVAGLKG
                     DSIYREDEYLKVATKYPNIAKKYFKEKGQKIEIIKLNGSVELAPIVGLSDVIVDIVET
                     GNTLKANGLEILEDICNISARIISNRASYRFKYEQIQNIIRLFEELDN"
     gene            16214..17263
                     /gene="hisC"
                     /locus_tag="JAM15_00070"
     CDS             16214..17263
                     /gene="hisC"
                     /locus_tag="JAM15_00070"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HAT6796665.1"
                     /translation="MREKESIRELRGYEPNHVNCKVKLDANEGSKRLFKYLIKEISDS
                     DIDLNLYPEDSYSDLKESIIDYINISGVNKKNLLVGNGSSEIIDLIIHTFVDKDEVIL
                     SFSPSFSMYSIYSQINGSKFIGVESDENLVINIDNVIEKVKENNPKIVIVCNPNNPTG
                     TILKREEIIKLLDSTNSLVVLDEAYMDFGEESMLSDVFKYDNLIVLRTLSKAFGLAGI
                     RTGYMLSNSSLINSVEKVRPPYNLNSLSDFIATRALRNKDVVKAYIKEVKEEREVLYE
                     EMIGMGIKAYKSQANFILFYSEIENLSQKLIDRGVLIRKFGGKLENYYRVTIGDKEEN
                     SMFVGAIRDILKKEK"
     gene            17266..17844
                     /gene="hisB"
                     /locus_tag="JAM15_00075"
     CDS             17266..17844
                     /gene="hisB"
                     /locus_tag="JAM15_00075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazoleglycerol-phosphate dehydratase HisB"
                     /protein_id="HAT6796666.1"
                     /translation="MRIWKVERNTLETQILVELNIDGSGKAEIDTGIGFLDHMLTLMS
                     FHGKFDLKVICKGDTYVDDHHSVEDIGIAIGEAFKNALGDKKGIRRYSNIYIPMDESL
                     SMVAIDISNRPYLVFNAKFDTQMIGSMSTQCFKEFFRAFVNESRVTLHINLLYGENDH
                     HKIESIFKAFARALKEGSEIVSNEIASSKGVL"
     gene            17846..18451
                     /gene="hisH"
                     /locus_tag="JAM15_00080"
     CDS             17846..18451
                     /gene="hisH"
                     /locus_tag="JAM15_00080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HAT6796667.1"
                     /translation="MNIIVDYGLGNIDSVSRGFRKAGIETKISSDIDEIKQADSLILP
                     GVGAFRDSISALDKLGLIPIIKEHVSKGKFMIGICLGMQLLYEKSYEYGEYEGLGLIK
                     GSIDKLDISLKVPHMGWNNLKFNKANDDILKYINEDDYVYFVHSYYANSSNEELIAFS
                     EYEKKIPAIVRKGNVYGIQFHPEKSGEVGLNILRAYGEMIK"
     gene            18448..19170
                     /gene="hisA"
                     /locus_tag="JAM15_00085"
     CDS             18448..19170
                     /gene="hisA"
                     /locus_tag="JAM15_00085"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HAT6796668.1"
                     /translation="MIIFPAIDIKDNKCVRLTQGEFDKVNVYYDNPLEVAYKWKNEGA
                     EYIHIVDLNGARSEFGINTKIIEDIANNIDIPIQVGGGVRDKGKVKSLINAGVTRVIL
                     GSIAIENLNLVEELVNEYKEKIVVSIDAKDGKVAVRGWEVVSDVDSLTLCKQLEKIGV
                     QTIVYTDISKDGMLQGPNFDIYERIAKETSLNVIASGGVTSIEDVKRLKAMNLYGAII
                     GKALYDKKIDFKEAQQLCLLGE"
     gene            19152..19910
                     /gene="hisF"
                     /locus_tag="JAM15_00090"
     CDS             19152..19910
                     /gene="hisF"
                     /locus_tag="JAM15_00090"
                     /EC_number="4.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HAT6796669.1"
                     /translation="MLTRRIIPCLDVRNGRVVKGKKFKDIVDVDSPEVLGKFYSDCGA
                     DELVFYDITASNEERKTSLEFVTKVAENINIPFCVGGGVNKLEDFTDILRKGADKVSI
                     NSSAVKNPELIREASLKFGAQCVVLSIDAKKNEEGSWSVYVKGGREKTNLDAIEWAVK
                     GVELGAGEIVVNSMDEDGMKNGYDIELLSKITSLVNVPVIASGGAGKKEDFYEAVNKS
                     NVDGILAASVFHFGEIKINDLKKYLKDMGVEVRL"
     gene            19938..20606
                     /locus_tag="JAM15_00095"
     CDS             19938..20606
                     /locus_tag="JAM15_00095"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HAT6796670.1"
                     /translation="MDNKCNNVYSDEVEKFIRSIKFDDKGLVPVVVQEVVSKDVLMLA
                     YMNKDAIKKTLKDKVACYFSRSRQELWVKGETSGNTQKVVKMSYDCDVDTILLFVEQT
                     GVACHTGNYSCFYRDLFDDSSKMELEVQTNILKELYDLINERKNNPVEGSYTNYLFEK
                     GIDKILKKVGEESSEVIIASKNTDKSELIYEISDLVYHTLVLMIEKGVEIDEIKKELL
                     KRRK"
     gene            21401..22729
                     /locus_tag="JAM15_00100"
     CDS             21401..22729
                     /locus_tag="JAM15_00100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAT6796671.1"
                     /translation="MGSNELKKTLGVSAALSTVVGSVIGAGVFFKPQAVYTLTGGAPG
                     LGILAWLIAGIITITAGLTAAEVSVAIPKTGGMMVYIKEIYGDKLGFLTGWMQIVLFY
                     PGMMAALGVIFGEQASALIGSPSLLLPIAIGIIVIVAGLNMLGSKTGGVIQTVSTICK
                     LIPLILIMVVGFIKGGGNNPILTPMVGEGLSLGSVLGQVLIAILFAFDGWMNVGTLAG
                     EMKNPGKDLPKAIIGGLSVVMAVYFIINLAYLWVLPANELSNYASPASAVAEVIFGSM
                     GGKIISVGILISVFGALNGFLLTGSRVAYTLATDKTLPKYGIFSKLNSAQVPANAIAL
                     VSVIASIYALSGQFNLLTDLAVFATWIFYVLTFIGVMKLRKTHPNIPREYKVPLYPIV
                     PIIAIASGIFVVVNQLCFAGMKTTMISIGGLVITAIGLPVYAYMTRGIKR"
     gene            23484..24317
                     /locus_tag="JAM15_00105"
     CDS             23484..24317
                     /locus_tag="JAM15_00105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HAT6796672.1"
                     /translation="MRNKKKKINRKKLYLLLSAIVVCLAFIVVGVRVSSLNMKENEIS
                     RNAKLSSSTITDIVSNTSIEVSKGPSKSSGKIAYITIDDGPSKFTDEMIKTLNKYNVK
                     ATFFMIDGNMKEYPQQVKNIIKNGNTAGFHSVSHDIHKLYVTSTSAKEEFDTNDQTFY
                     KITGKHSKVIRIPYGSKPYTPQASYQALVDAGYKIWDWDLDTEDWRSNSSQIVQNVKN
                     HIKNRKGEDKDQLVVLMHEKKQSAEALDSVLKLLSDEGYEFAPVDQNQIPKNYWLRNL
                     E"
     gene            24386..25342
                     /locus_tag="JAM15_00110"
     CDS             24386..25342
                     /locus_tag="JAM15_00110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAT6796673.1"
                     /translation="MNKKLYIGMVGILSLMMVGCNKSLAKVNDVEITKEQYKKTKAVL
                     SATNNYINGQSLDELEKTLDKKGRNKLENVIISFMVDNELLYQEAKDKGLTPSKSEVD
                     SKYQELEDKMNLNTSYKEKMDKAGVDKEYLKQEISRDLAIDKNKKAFEDRINISDNDM
                     EAYYTSHKKDFNVEEVSASQILISTLDKNKKEVSKDKKEALKKKADNILTKIKNGESF
                     ESLAKKYSDDKATGKNGGQLGYFTKDDKNAEFTKEVFKLKKNEVSNVFETSYGYHIVK
                     VTDKRERQKSFNECQSLIRESILNEKYIEHIKKLNEDAKIDR"
     gene            25394..25876
                     /locus_tag="JAM15_00115"
     CDS             25394..25876
                     /locus_tag="JAM15_00115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAT6796674.1"
                     /translation="MFKSLKRTKVEKYIIDNKDSFYRIAYSYTKNEEDALDVVQEAMY
                     KALYSVENIKEVNYIKTWFYKILVRTSIDFIRKNRKYNNMTDIDLIDETGEYDKYTDL
                     DLRRALEELPIEYKSIIILRFFEDLKIEEVAIILDENVNTVKTRLYTALKKLKLKIEE
                     "
     gene            25888..26757
                     /locus_tag="JAM15_00120"
     CDS             25888..26757
                     /locus_tag="JAM15_00120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma-V factor rsiV"
                     /protein_id="HAT6796675.1"
                     /translation="MTSKERLNKLKDEYHKIPIPKKLDTIINHEKIENIYREKNKKVN
                     RLRFKVAIAFACIFTVLVNISPVFADNFSKIPVIGAIVEVITIKNYSLKSENYEAEID
                     IPKIRGLKDKNLEQRLNSSFMEDGKRLYHQFQERMEKIQSSKNKGYKSLSLSYSVKNN
                     SKKFLSIEMTKNEIEASSYVSKVHYTIDKKRQIVLTLPMLFKDDKYIKVISDNIKEQM
                     REQMKKDSTKSYFIDQKKDLPVEDFKTINKYQDFYFNKNEDLVICFDEYEVAPGYMGA
                     VEFVIPYKVIKDL"
     gene            26800..27555
                     /locus_tag="JAM15_00125"
                     /pseudo
     CDS             26800..27555
                     /locus_tag="JAM15_00125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861251.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
     gene            27597..28418
                     /locus_tag="JAM15_00130"
     CDS             27597..28418
                     /locus_tag="JAM15_00130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HAT6796676.1"
                     /translation="MNIYEQAIRLIENNEDFAFATITSHSGSTPRETGAMMIVKNDST
                     IFGSVGGGSVEAECIKHAINVIKNRESMLYKFTLNKSDVAKLGMICGGTGEIQIDFID
                     SKLKSNIEKFNKRLKENTSKAYIFGAGHISRDVAVILSLLEFRTVVIDDREEFANYER
                     FPESEVVVLDSFENIPDFPTDENSYIIILTRGHLYDSSALEWALKRETGYIGMIGSRT
                     KIGLTYEKLMKKGFKKEELSKVHAPIGIKLNAQTPAEIAVCIAAELINCRANKEK"
     gene            28423..29184
                     /locus_tag="JAM15_00135"
     CDS             28423..29184
                     /locus_tag="JAM15_00135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HAT6796677.1"
                     /translation="MNTGSKDIDTLNVNFRGIEIKAVLVYKNRKNISIKIDPFGKIIV
                     MSPPKISKKIIKDIIIEKGDWILKKSEKYKGREEVYKQRMFITGEKFLYLGEEYHLVI
                     KELLKDSVKKSNCRITINEYQIVVQTNDTSTDFIKKSLKSWYKMESERIVLERIDFLK
                     LNCEIMKQLVPASVKVKEQNKRWGSCTAQKNIYINSKISMARLDVIDYVIIHEFSHLV
                     HMNHSKKFYDLVKSIMPNYKDKENWLKINGYKIII"
     misc_binding    29345..29602
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            29715..29954
                     /locus_tag="JAM15_00140"
     CDS             29715..29954
                     /locus_tag="JAM15_00140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796678.1"
                     /translation="MENTVYAKLNQGIDSFLRVAMTLRRREVDIQSISMTVDNMNNSG
                     IKLIVNEEKTSLDSVLNHMKKLHDIREITVERMRH"
     gene            30258..31253
                     /gene="ilvC"
                     /locus_tag="JAM15_00145"
     CDS             30258..31253
                     /gene="ilvC"
                     /locus_tag="JAM15_00145"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HAT6796679.1"
                     /translation="MKMARMYYEKDVDLEVLKNKKVAVLGYGSQGHAHAQNLRDNGVH
                     VMIGLYDGSKSAQKAKEDGFEVKSVAEATKESDLTMMLMPDEKQKKVYEESVKDNLKE
                     GQTLAFAHGFNIHYNQVQPPEFVDVVMVAPKGPGHLVRNVFTKGSGVPALFAVYQDYT
                     KKATETVLAYAKGIGATRAGVLETTFKEETETDLFGEQSVLCGGISELIKLGYKTLVD
                     AGYQKEVAYFECLHEMKLIVDLIYEGGFERMRYSISDTAEYGDYVSGKRVITDAAKQG
                     MQNVLEDIQNGKFAKAWIKENEEGRENFLKTREEEYNTEIAEVGRNLRSMMSFLK"
     gene            31306..32994
                     /gene="ilvB"
                     /locus_tag="JAM15_00150"
     CDS             31306..32994
                     /gene="ilvB"
                     /locus_tag="JAM15_00150"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic-type acetolactate synthase large
                     subunit"
                     /protein_id="HAT6796680.1"
                     /translation="MNGAKVILECLKKEGIDTIFGYPGGAVIPLYDALYDYSDDFKHI
                     RTSHEQGLVHAADGYARSTNTVGVCFTTSGPGATNAITGIATAFMDSSPMVVISGQVP
                     TSLLGKDSFQEIDITGATLSMTKHNYLVRNTKELVPTIKEAFRVANSGRKGPVLVDVP
                     KDLFLAEMDFSGEDYDLCQIDDYMDYKSDFDLDDETNIKLLNEAIDIIKESKKPVIYA
                     GGGVKSSDSEEILEKFATKIDTPVLNTLMGLGNIDRKNELSLGMVGMHGSRESNLALS
                     NSDLVIAIGARFSDRVISKSSEFAKNAKIIHIDIDPSEISKNIESNVSLVGDVKLVLS
                     LLIERVESKNNSNWKEEIKTFRKSEGVQTYEFHPQNILKKINEKYETLKKPTVVVTDV
                     GQHQMWSAKYWNFKGNKSFITSAGLGTMGFGLGAAIGTKVGNVDKNVVLVTGDGSFRM
                     NCNELATVANYNVPMLILLLNNRTLGMVRQWQKLFSNQRYSQTDINENVDYVKLVNAY
                     NIDGYKVSSMEELGKALDMIDFNKPVFLQCDIDKDYDVYPIVAPNDALENLICN"
     gene            33205..33882
                     /locus_tag="JAM15_00155"
     CDS             33205..33882
                     /locus_tag="JAM15_00155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HAT6796681.1"
                     /translation="MFKHDKALLKEVKVERPNPQYAVLMQEQLGGANGELKAAMQYLS
                     QSFRIKDPQIKDLFLDIAAEELSHMEMVAQTINLLNGHDVDYNAVNTGEIETHVLTGL
                     SPVLINSSGAPWTANYVTVTGDLVADLLSNIASEQRAKVVYEYLYRQIDDKYVKETID
                     FLLNREEAHNALFRDALNKVKDTGSNRDFGVTEDSKLYFDLSTPGPNHDTKIDINPPS
                     FEKPLKK"
     gene            34056..36092
                     /locus_tag="JAM15_00160"
     CDS             34056..36092
                     /locus_tag="JAM15_00160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin domain-containing protein"
                     /protein_id="HAT6796682.1"
                     /translation="MDSNRKPNNLINEKSPYLLQHAYNPINWYSWNDEAFKKAKEEDK
                     PIFLSVGYSTCHWCHVMEKESFEDEEVAEIMNRNFVAIKVDKEERPDVDSVYMTVCQA
                     MTGSGGWPMTIIMTPDKKPFFAGTYFPKYSRYNRPGVIDLLENVSEKWNTSRDILIKS
                     GDEIIEALKDDFGVKNTEGDLSKEMLSSSVRVFKAIYDEKYGGFGNAPKFPSPQNLMF
                     LMKYYSIEKDKDVLKMVEKTLDGMYRGGLFDHIGFGFSRYSTDKKWLAPHFEKMLYDN
                     AMLTIAFLDAYKITKKELYKEIAIKTIDYVVREMKDKEGGFYSAQDADSEGEEGKFYT
                     FNPLEIIEVLGEEDGTFFNNYFDITSSGNFEGKSIPNLIKNKEYERHNEKIADLSKKV
                     FEYRKERTSLHKDDKILTSWNALMIVALTKAYSTLKNDIYLEYSNKCLNFINNNLVNE
                     SGRLLARYRDGSSDYLAYLDDYAFLIWAYIELYESTFNMKYLEKALNLNESCINLFWD
                     YEKSGFYIYGKDSENLIARPKDLYDGAIPSGNSVQLYNLIRLAKITGDNRLEEMSYKQ
                     LKLYVDNVKSSPTGYSFYMLSLMFELYSTKEIICIFKEDSDLIAFKELISKNFIPNAT
                     FLAKKYNEENTIIGFLNNYRLKDDKISYYVCQSNSCSQPINDLQKLKDMILGVE"
     gene            complement(36283..36849)
                     /locus_tag="JAM15_00165"
     CDS             complement(36283..36849)
                     /locus_tag="JAM15_00165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAT6796683.1"
                     /translation="MDYSNELKELFLMNQTYATLFTLTNKIQIEGDKYFGILTSRQYM
                     TILSILHLPEEETTLNNIARKMGTSKQNINRLVANLEKNGYVDVIPSPHDKRAINVKV
                     TDLGKKVMVTCSRTGINFMADVFHEFTKDELETLWSLLKKMYRFNGEEQDGFEEDANF
                     MEYEEIDKIKSEALEEFVKRRNRVNKKD"
     gene            37137..38072
                     /locus_tag="JAM15_00170"
     CDS             37137..38072
                     /locus_tag="JAM15_00170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAT6796684.1"
                     /translation="MKCTNFTFKGEEGLDIYTYKWEDENIKKPKAVIQIAHGMAETAQ
                     RYETFAKVLTKNGYIVYINDHRGHGKTAKIIENVGHLAEKEGFRCLVEDMYTLTNIIK
                     KENEDLPIYLFGHSMGSFASQRYIMDYSNNLSGLILCGSNGKQGIILNLAHLIINREI
                     KKYGRRSKSNKINNLIFGGEIIRRNEKTKFDWLSRDKEQVEKYINDPFCGVVCSCGFF
                     YDLVQGLKEIEDKENLKKVPLDIPIYIISGDKDPIGKNGKGVLRLRDRYIKLGVKDVT
                     CKLYKDGRHELLNEINREEVFEDIICWLNNKIEIL"
     gene            38537..39751
                     /locus_tag="JAM15_00175"
     CDS             38537..39751
                     /locus_tag="JAM15_00175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6796685.1"
                     /translation="MQIKIGKVIQRLRKERNLTQEQLAKFIGVSTPAVSKWESGNSYP
                     DIELLPLLADFFNVSIDKLLNYKIDLSEEEVMKIYKELESGFARIEIDLSTEEPKEEF
                     RQDLESVKKLSNMYIEKYPKSYLLKLRICSLYQMYSYKFGKSELNDRVKETTNILEDI
                     VRNTDDIQIKETALIILSSAYCMLEDYEKAELYLNMIHKSIGDTSVNLAMIYLKQNRL
                     EEAEILLQNKLFSNVFNISMDCKGIINVYKNQYKELKKKLENRNFNKNAIEREMEYIK
                     NKLLGYANLSLEIKKMLSEDKGAFFSMYVDYMELSLIFLFFNMKEEAKKALYSLKEIL
                     EKYPIHESLDVSQMRFFDKVESKNLYTFNIYTNLLIVLNDDSYNELREEPIFKDVIEK
                     ILDMEKMLKNKE"
     gene            complement(40171..40692)
                     /locus_tag="JAM15_00180"
     CDS             complement(40171..40692)
                     /locus_tag="JAM15_00180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAT6796686.1"
                     /translation="MKFERLRTSENKLYYKAMELYKISFPFHEQRKSSLQAEILKNKE
                     YQFNLIYDKNQFVGIILCWETDDFIYVEHFCIFPEMRNNRYGQRALELLNKKGKTIIL
                     EIDLPIDEISIYRKAFYERVKYKTNNYEHIHPPYHEKFNGHNLIVMSYPEKLSKMEYD
                     KFNHYLRNNVMSF"
     gene            41048..41845
                     /locus_tag="JAM15_00185"
     CDS             41048..41845
                     /locus_tag="JAM15_00185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF348 domain-containing protein"
                     /protein_id="HAT6796687.1"
                     /translation="MEKREKRIIISSLLSVSILMGLVSIYSILNKEDIILTVKGQEQK
                     VSSFKKTVEELLDEQGVKYNSEDKINPSLDTELKDDMKIKVVKVTKSKKEEIEKIPFD
                     TKHVNDSNLLKGKSKVYQEGQEGEKKLVYNLTYHDGKLVKKVLSKEVISKEPTTKIIK
                     YGTKEKVLIASRGANIRGGKHMKVVATAYAGDTITSTGTTPRWGVIAVDPRVIPYGTK
                     VYIPKLGMTFVAEDCGGAIKGNRIDIFMNSEGKASNWGRKSIDIYLH"
     gene            41955..42545
                     /locus_tag="JAM15_00190"
     CDS             41955..42545
                     /locus_tag="JAM15_00190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylesterase"
                     /protein_id="HAT6796688.1"
                     /translation="MKIVCLGDSLTYGFGVSRSNSWTNIVNKETRLEIVNKGINGDTT
                     SGMLARFNEDVVKNSPDIVFIMGGTNDFIAGAGNEIINSNIMAMVHQSYSKNIIPIIG
                     IPLKLDIPNVREDWSCFTDFNIVSQNLESYSYWIKKFCMTFNTNFVDFYSEYNKNMEL
                     EGYKKLYFDGLHPTKEGHRIMADIFINSINKYIEEL"
     gene            42611..44308
                     /locus_tag="JAM15_00195"
     CDS             42611..44308
                     /locus_tag="JAM15_00195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HAT6796689.1"
                     /translation="MDYTKTYEEWIKGSYFDEDTKLELENIKNNEKEIEDRFYKDLEF
                     GTAGLRGIIEAGTNRINKYTVRRATFGLANYILENTTKEETSRGVVIAHDNRHKSRQF
                     CIESANTLAACGIKAYIFDSLRTTPELSFAVRSLNAIAGIVITASHNPPEYNGYKVYW
                     EDGAQVMPEIANAITEKVNSIHDYSTIPTLTEANKNLVVLLDESQDTKFIEAVKSQII
                     RKDLVKNVGKSFKIVYTPLCGTGNVPIRRALKEVGFENIIVVPEEENPDPNFAGLDYP
                     NPEEKKALNRGILLAKEKGADLVIATDPDCDRVGVAVKTTTGEYALLTGNQIGGMLTH
                     YIIEGLKENNKLKENPTIIKTIVTSEFGADIAKANNVDVLNVLTGFKFIGEKIKLFEQ
                     NKNRSYVFGYEESYGYLVGTHARDKDGVVSSLLISEMAAFYYSKGISLYDGLIELYKK
                     YGFFKEQTISLTLKGIEGVEKIKEIISYFRENQIDYINSIKVVDKKDYKNGIDNLPKS
                     NVLKYFLEDESWVAIRPSGTEPKLKFYIAVKGASDIEADKKIQGLKKYIDDMVEKLK"
     gene            44522..45361
                     /locus_tag="JAM15_00200"
     CDS             44522..45361
                     /locus_tag="JAM15_00200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HAT6796690.1"
                     /translation="MFGIDKKLIEYIIAKSNYSELSSKSAEVSFFLMLSIFPFLIFTI
                     SSIAYIPILHLNKYIALFRNMMPEGAFAVLSSIIVSAIDNRNLKFLAVSFVLTMWTFS
                     RAVKALIKGMNRAYKVKETRSFFKILSISFLFTIMLLVLIFLSMIFLVYGEKIGYFIF
                     NLVGLDEIFIKIWDILRYTVGIITIIVIFTLLYKYTPNKKLTIKESAPGAIFATFAWF
                     LVSFLYSYYTNYYANYEVIYGSIAEIIVLMTWMYFSSWSIVIGYEVNSRLYFRKIRHE
                     MLK"
     gene            45878..47734
                     /locus_tag="JAM15_00205"
     CDS             45878..47734
                     /locus_tag="JAM15_00205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HAT6796691.1"
                     /translation="MDIHNKYVNFIKNIPVPFLYCRIVKRQEDIEYRVEYISKGMGKV
                     LQLEEGICDKNILDVLPVFKSKKYFKELFSNEVDCIKRYIPTLKNWINIKKQIIGDSY
                     IILYFGKIVFDYRQIIDSFDKKEKVAYIKDEEGIYIDCSENLIPILNNNIKTTKDIFG
                     KNDIEVWGENTGKLFRDDYRGGVSSKKRFLQNLFEYEETFFMVEKYFLYDEDELLGTI
                     GIIDNIIYSGYSNRNYNSKDLMKMIEHSIPENMFYKDVYGNYIGFNSGFLNLACMNKE
                     ELLGKNSYKISEEEALINKIFESDKGVVENKKVVTFELNVSINDENKCIEITKRPFFD
                     SYGSVIGIIGTARDISRRKRLEEEMDKTRMEFFANLSHELRTPINLISSSLQVIEKKE
                     ADLIESNDTLKRNLGIIKQNGNRILRLVNNVIDFTKMQSGYLDFKPEESDIIAFIEEI
                     CMSVADFASQNNIQLTFDTEIEEFSMLFDSEKLERIILNLLSNGIKYNKKDGKINIFL
                     YVKDNVFNMKISDSGIGIPKEKIDKIFNRFEQIDNELSYRVKGSGIGLSLVKSLVELH
                     EGSISLKSQLGIGSEFIVSLPVRSENNIEKYNHKREISNELSKKLEIEFSDL"
     misc_binding    47817..48057
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    48123..48358
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            48443..49660
                     /locus_tag="JAM15_00210"
     CDS             48443..49660
                     /locus_tag="JAM15_00210"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HAT6796692.1"
                     /translation="MENKVKIGVLGYGVVGSGLIDIIDNNKEKRSIEIVGILVNNLEK
                     HKDKKYSNIITNNIDDIFNKDIDILVEVMGGLEPSLSYIKKALNNKIHVVTANKDLLA
                     ECGDELAKLASENKVSIKFEASVAGGIPVLKPIIESLEGNNIDSINAILNGTTNFILS
                     KMYDENLSYDMALRQAQELGFAEANPESDVLGYDAARKLSILSTLAYDNRVYWKDVYL
                     EGITDIDEKDIEYAKKLNCKIKLIGQSKYENDKVSAFVRPVLVEKDNILARIDNEFNA
                     VIVNGDSVGEVSFVGKGAGSLATGSAVYSDVIDIIDNRVSSIDSFTKDKIQVNKIVRE
                     KCGALLRFKKCNKDEILNIVENCLVKFDILNDDDELAIMVYADSEYEINNSLCLIKDK
                     GYCEKMNKMLKIS"
     gene            49774..50268
                     /gene="cdeM"
                     /locus_tag="JAM15_00215"
     CDS             49774..50268
                     /gene="cdeM"
                     /locus_tag="JAM15_00215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeM"
                     /protein_id="HAT6796693.1"
                     /translation="MENKKYANGGYSEDWYERGESTAKWFQNDREEYERAAYDEDRER
                     RGSNCGCSDSGGNRPRNCERFRREAEIREREAREAFCESSERKKEALAYECEARKLWE
                     EAEKYWDEYSKYNYKGIEYLAEAARLFDEGMECEARRNGNNGGNNNNCCHKCHKCNCN
                     CCRK"
     gene            50533..51798
                     /gene="hisD"
                     /locus_tag="JAM15_00220"
     CDS             50533..51798
                     /gene="hisD"
                     /locus_tag="JAM15_00220"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HAT6796694.1"
                     /translation="MKSIKTSSMKEKVDEKILREQVSSIIEDIRNNKDVALKKYNEKF
                     DRNTRDEFRITKEEIKEAYKHVDDEFINNLKIAAKNIREFAKAQKLSFENPFEKEIYP
                     GVILGQTNIPIESCLAYVPGGQYPLFSTALMLIIPAKVAGVKRIVACSPTMKNTEKIN
                     PKTLVAMDIAGADEIYATGGVQAIAAFTYGTEKINPVDIIVGPGNKFVTEAKRQCYGQ
                     VGIDFVAGPSEVLIIADETSNPVYIAADLLAQCEHDLNARGILLTNRLEVAQKVEKNI
                     ESMLKDLPTKDIAYSSWENNGEIILVDDMEEAIKISNFYAPEHLEVAVNEYNDICDRL
                     TNYGSLFIGNLSAEVFGDYVSGTNHTLPTLKASRYTGGVWVGTFIKTCTKQIFNEKAI
                     QSLAPVAEKLAKEEGLYAHAKAAEVRFKK"
     gene            complement(52001..52753)
                     /locus_tag="JAM15_00225"
     CDS             complement(52001..52753)
                     /locus_tag="JAM15_00225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAT6796695.1"
                     /translation="MSYFQYQGNSCFYKEYGQGKPIIFLHGNTGSSNMFKALVPLYVE
                     NFRCILIDFLGNGQSDRVSQFSPDIWHDEALQTIALIEHLNCGKVGLIGTSGGAWAAV
                     NTGLERPDLVEAIIADSFDGRTLNDNFIDNLITGREKSKQDIQARKFYEWCHGKDWEN
                     VVNLDTKALLQCANKKRPLFHKELCKLEMPILFTGSKEDEMCRHNLEEEYKQMATFIS
                     KASIHIFSQGGHPAILTNADEFAQLAKVFFKY"
     gene            complement(52871..53140)
                     /locus_tag="JAM15_00230"
     CDS             complement(52871..53140)
                     /locus_tag="JAM15_00230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796696.1"
                     /translation="MSYQNSIDLLPKELIEQVQEYIDGKVIYIPKKQEHKKHWGENTN
                     TKQVLASRNSQICINFQNGMSIKQLSEKYFLTEKSIQRILKQQNL"
     gene            53615..54709
                     /locus_tag="JAM15_00235"
     CDS             53615..54709
                     /locus_tag="JAM15_00235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAT6796697.1"
                     /translation="MKNIVGKPQTIKKVNEDLIKNIIKNEGPITKPEISSITELSLAT
                     VNKIVEQLALKNEVKVSGLSESTGGRRAQLFEINANLEHIIALYYYRNCCIGVVANLL
                     GEIIYQEEFNIRMDTYENVNQDTFFVIDTLIKKEKGNNIRAIGIGVPGVVKKGVVKNI
                     PTIKSWEGINLENLIKSKYNTKVFIENDTNITTIGIYQKQYKDKYKNMALMYLEDGIG
                     SGIVINGELYLGSTNFAGELSYLNIEFGKYNSNNLNLEDYIMSLRKRYLESKDNKFKK
                     EILSIISNFIRTLVCVLNPQAMIIQCSILTKSDMEFIEKDVSNNVGEENFPKLIKVES
                     LRERSINGVISMCLKETDYQYSLSNKKGGY"
     gene            54711..55661
                     /locus_tag="JAM15_00240"
     CDS             54711..55661
                     /locus_tag="JAM15_00240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine kinase"
                     /protein_id="HAT6796698.1"
                     /translation="MKYLVSIDGGGTKTKFCVSDLDGNILKEHTTGSTNYKSVGIKKT
                     YENINNGFKKILKDLYIDYDDIEYTVFGISGCDSPNDYKIIMDEILKIGINKEKIYLA
                     NDAVLAFYAQADSPGLVIVAGTGSIILGIKEDGEIYRVGGWGYNFSDLGSGYDIGRKL
                     LKKVLLYCDECHEYSDLFSCVLDFFGANSFEQLAYMITDINDNVEIANLASLVIDCAE
                     QGDKLAIEILRESSTELSKLAQVILRKISNPMKMDKSEINIVLSGGTLNKTVYAQMLM
                     NNLKTENTDKNLKFISQENQPVYGGIRLAMALANRRVKHG"
     gene            55654..56838
                     /locus_tag="JAM15_00245"
     CDS             55654..56838
                     /locus_tag="JAM15_00245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796699.1"
                     /translation="MDRKKVIVQIFTGGFKAKEIKFNDIKCKLLELLDCIDIEKVIMV
                     WSVDEELYVETKKLLNKYNVELYLWLPCFSEIGLLEKSNLLIDYMGKEVKGYALQEDE
                     NFEFYCPNNKENIKNIKKIYSTYFSDIKLDGIFLDKIRYGSFSNKLNGVFNCFCKDCL
                     NIYEKNNIDKKSLMREMNNVSKGVIDNEDTPFGITEYINGKYKFKNKIWEDFFETKNQ
                     NIYKSLLEISSYFKSKGLKIGIDTFSPFISYFTGQDLKKLQEVADFIKPMMYRTTKAP
                     AGLPFEFERFIDESIHKNKEIGKRNFLDILGIKEYEGDVYPIEFVLEEIDFMTRNLNK
                     DIYVGVEINKKEIIAPVTPKYISENISNINKTTVKGYVLSWDLLSAPKENIDEIIKWF
                     RN"
     gene            56851..58347
                     /locus_tag="JAM15_00250"
     CDS             56851..58347
                     /locus_tag="JAM15_00250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HAT6796700.1"
                     /translation="MSKILEMQQIYKSFGKVDVLKGINFELEKGEVRALLGANGAGKS
                     TLIKILGGVHSQTKGKVILTGNEIMFKNSHHSKENGISIIYQELSLIPTLTVLENIFL
                     GREILKGSVFLNKKDMLEEYMKICEDFDFNIDPHTVVSNLSVANQQMVEIMKAVSCNS
                     EIIIMDEPTTSLTNNEKDGLFKIISRLKSKGKTIVYISHILEEVFKVCDSASIMKNGI
                     MIGTYDVEDLTKLKITQLMTGNDNHKLIEKKDYTFAKYEEPPVLEVKNISWSNKIKNV
                     SFKVYRGEVVGLAGLVGSRRTEIINLIFGIDNKDSGDIFINGKKVDITSPKVAIKNKI
                     GLIPEDRKNLGLILEQAIYTNSSSVQIDKFKKFLFIDRNKEIEFSKKGVKELGIKVSD
                     VKQEVKELSGGNQQKVVVSKWLEKDLDLIIYDEPTKGIDIAAKEDIFNTIKEFSSEGI
                     GVIFISSDLEEVIRVSDRILVTREGSIVDDLKNENIQVQDIMNSIFNV"
     gene            58370..59320
                     /locus_tag="JAM15_00255"
     CDS             58370..59320
                     /locus_tag="JAM15_00255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6796701.1"
                     /translation="MKKAFEKLNLRDYGVLLGFLALCIAISIATPSFLGKQNILNLLR
                     QSSIIGIISAGMTFVIISGNFDISVGAVAALAGAITMKFATGGTNLFASMLLGVAICA
                     VIGLINGIVVAKINVPSLIATMAMVTIVRGLLLMLTGGYPITENIPILDYIGNGYLFN
                     IPIPVVIFFIVVLVSFIVLNKTKFGRYVYSVGGNQEASKLNGINVDSHKVKVFIINAV
                     LAGIAGIVLTGRLGTATAIAGEGYDMDAIASVVIGGTSVAGGSGSVLKTVIGVLLMSV
                     INNSFNLLGIDVYFQYIFKGLIILAAVGFDSYSKKKLASR"
     gene            59341..60303
                     /locus_tag="JAM15_00260"
     CDS             59341..60303
                     /locus_tag="JAM15_00260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAT6796702.1"
                     /translation="MKKLMKHLALLLSLVMIFGLVGCSNGGDKEKNGEKKIAVLLPGS
                     TGYFVATKQGIDAKSKELGVSVEYADAQWDASKQLSQAEDFMAKGVDMIALCGVDSAV
                     SERIVKAANDSDVPIVAFTNSIGSNPTGEFKGLVTYIGQNEEETGALTGKIAKNLLGE
                     TGGKAVLIEGVPGTTPQVLRKKGLEKELKDSNIEIVYNQTSNWEKEQALKVTEDLIQK
                     KTDFNVIICQDDNSATGAGQALKDAGLKDKVKVIGLGGSKDGLKAITDGLIDGTTYMS
                     AVEEGGLVIEKASKFLKGEKIEPVTQIKQVEVNKDNISEFKGEW"
     gene            60675..61307
                     /locus_tag="JAM15_00265"
     CDS             60675..61307
                     /locus_tag="JAM15_00265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAT6796703.1"
                     /translation="MARRLFLERIGLIFLGSAILAFGVYNFYYLNNITEGGVLGILLL
                     LKNLFNIQPAIANVVIDGLLLLVGYKFFGKKFLIYSIVASITFSVLYDLFEAIGPLVP
                     QSQNMLLSTILAGVTVGTGVGIVVKAGCASGGDDALALVISKTTSLNIGQVYLATDVI
                     VLLLSLFYLSAFDIFYSLIAVTISGKVIDFIYYHGKSLDMDISNDIVPEC"
     gene            61733..61810
                     /gene="kdpF"
                     /locus_tag="JAM15_00270"
     CDS             61733..61810
                     /gene="kdpF"
                     /locus_tag="JAM15_00270"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020062503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit F"
                     /protein_id="HAT6796704.1"
                     /translation="MWFLAVVIIMLIIYLVYALINPEKF"
     gene            61851..63533
                     /gene="kdpA"
                     /locus_tag="JAM15_00275"
     CDS             61851..63533
                     /gene="kdpA"
                     /locus_tag="JAM15_00275"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015391009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpA"
                     /protein_id="HAT6796705.1"
                     /translation="MFMVQIVIVLAIFMILVIPMGKYLYHIATNQKTFGDRLFDKVDN
                     FIYKVCSIDKKKEMNWKQYALALLFTNAVMVFIGYIILRTQSMHIFNPSGIKSMEQGL
                     SFNTIISFMTNTNLQHYSGESGLSYFSQMTVIIYMMFTSAATGYAAAMAFVRGLVGKK
                     KTLGNFYVDLIRITTRVLLPGALIIGLILVTQGVPQTFAGTETVTTIEGKLQDIARGP
                     VAALESIKHLGTNGGGFFGSNSSHPFENPTIISNIVEILSMMILPGACVVAFGHMIKN
                     KKQGWVVFGAMSIIFLIGLVVCFKAESAGNPILSQLGLNQSMGSMEGKEVRFGIAQSS
                     LFTTVTTSFTTGTVNNMHDTLTPLGGLVPLLNMMLNVVFGGKGVGLMNMLMYAIIAVF
                     LCGLMVGRTPEFLTKKIEGKEMKLIALLIILHPLLILMFSGLSVAIPAGLEGISNPGF
                     HGLSQVLYEFASSAANNGSGFEGLGDNTMFWNITTGIVMFFGRYVSIIVLLAISSLLA
                     SKKAVNESIGTLRTDNFTFTIVLVLVVLIVGALTFFPALALGPISEHLVLWH"
     gene            63558..65615
                     /gene="kdpB"
                     /locus_tag="JAM15_00280"
     CDS             63558..65615
                     /gene="kdpB"
                     /locus_tag="JAM15_00280"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010236550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="HAT6796706.1"
                     /translation="METKKTKFITKDIFKTSIIEAFKKLNPKYMMKNPVMFVVEIGFI
                     VTLILTIVPSLFGDEGNNLRAYNGIVTIILFITVLFANFAEAVAEGRGKAQADTLKKT
                     RKDTVARVIDTLGNEKMISASELKLGDIVLVNAGEVIPNDGEVIEGIASVDESAITGE
                     SAPVMRESGGDFASVTGGTTVVSDWLKIRITTKPGESFLDKMIALVEGASRQKTPNEI
                     ALNTLLVGLTLIFMVVLISLYPMANYAGVKIPISTMIALLVCLIPTTIGGLLSAIGIA
                     GMDRVTRFNVIAMSGKAVEACGDVDTMILDKTGTITYGNRLASEFIAVGNADSKDLIN
                     YSVMCSLKDDTPEGKSIVDLGMKLGSTGKTKEAEEAEFVEFSAQTRMSGINLADGRAI
                     RKGAYDSIIKRVKESGGTVPEDLEENVNRVAKLGGTPLVVCVDNEIYGIIYLKDTVKS
                     GLVERFARLREIGIKTIMCTGDNPLTAATIAREAGVDGFIAECKPEDKIDAIKKEQLE
                     GKIVAMTGDGTNDAPALAQADVGLAMNSGTTSAKEAANMVDLDSDPTKILEVVEIGKQ
                     LLITRGALTTFSIANDVAKYFAIIPAIFTLAIPQMEILNVMKLSTSFSAILSALIFNA
                     IIIPCLIPLAMKGVKYRPMKSQAMLMRNMLIFGLGGVIVPFLGIKLIDLLITPLVMVL
                     NLG"
     gene            65634..66260
                     /locus_tag="JAM15_00285"
     CDS             65634..66260
                     /locus_tag="JAM15_00285"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit C"
                     /protein_id="HAT6796707.1"
                     /translation="MKTLKPALLVSIVLLVVCGLVYPLVLTGVSQVAFKDKANGSMIE
                     VNGVKVGSELIGQSFTDARFFKGRVSSVNYNTYTKEDLVPDKDGNTSYGGVSSGSFNY
                     GATNPELHDRVQKDIEKFLKDNPTVKREDIPTDLLTASGSGLDPNISPASAKIQIPAI
                     AKASGISESKLQKIVDDNTSKKLFGVLGEDRVNVLKVNVEVAKILGLI"
     gene            66498..67406
                     /gene="cysK"
                     /locus_tag="JAM15_00290"
     CDS             66498..67406
                     /gene="cysK"
                     /locus_tag="JAM15_00290"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HAT6796708.1"
                     /translation="MLYNNALELIGNTPVVRLNNLGCTNGCSNIYVKLEKVNPAGSIK
                     DRAVYEMLEGLEQRGELKKGDVLVEATSGNTGIALSMIGKLKGYEVVIVMPETMSVER
                     RDLMKAYGANLVLTDGKAGMAGSIEKANELLKENPNYKSLKQFENKDNPNAHYKTTAV
                     EIMNDVKDLDIFVCGVGTGGTLIGTARYLKEQNPNIRVIALEPKKSPAISENKTGPHK
                     IQGIGANFVPENYDSSVVDEVILVDDEDAFDTVKLLAAKEGILVGISSGANIFGAIEM
                     AKKYPDKKIVTVAPDGVDKYMSMGIF"
     gene            67433..68023
                     /gene="cysE"
                     /locus_tag="JAM15_00295"
     CDS             67433..68023
                     /gene="cysE"
                     /locus_tag="JAM15_00295"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HAT6796709.1"
                     /translation="MFKKINKDIEYIMKNDPAARSKIEVFLLYPSVHAMIMHRMAHAL
                     YKKKKLFTARLISQISRFMTGIEIHPGAKMGEGILIDHGMGVVIGETAEVGNRVTIYQ
                     GATLGATGKDTGKRHPTVGDDVLIGAGTKILGPLNIGSNSKIGANSVVVKDVPNGATV
                     VGIPAKIVKIRNLEPVKKNKKEVSYEYDELDNVYYI"
     gene            68183..68371
                     /locus_tag="JAM15_00300"
     CDS             68183..68371
                     /locus_tag="JAM15_00300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HAT6796710.1"
                     /translation="MKANVNQDTCIGCGLCPSICPEVFDMKDDGKSHVIVDEVPSDAE
                     ESAAEARESCPVDAIDVH"
     gene            complement(68425..69294)
                     /locus_tag="JAM15_00305"
     CDS             complement(68425..69294)
                     /locus_tag="JAM15_00305"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003476304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HAT6796711.1"
                     /translation="MKLNRNDSCWCGSTKKYKKCHMDMDNKIDSFAKLGHIVPTHDII
                     KNESQIEEIKKSAVINTKILDYISDKIEIGMSTEDINKLVHDFTLQNGAIPAPLDYNG
                     FPKSVCTSVNNEVCHGIPSKDIILKDGDIINVDVSTIFNGYYSDASRMFMIGNVNENA
                     KKLVQVTKECVQKGLEVAKPWGFLGDIGDAINSYAKKNGYSVVREIGGHGVGLSFHED
                     PFVSYVSKKGTEMLLVPGMIFTIEPMVNEGTHEIFVDEENNWTIYTKDGKLSAQWECM
                     VLVTETGVEILTE"
     gene            complement(69491..70735)
                     /locus_tag="JAM15_00310"
     CDS             complement(69491..70735)
                     /locus_tag="JAM15_00310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796712.1"
                     /translation="MENNLNIAKKNNTELLQNDSLKVNLQIGVDFTLLSKSLKAFYKK
                     EKDFYCIALAPCNVSSEKANRKISIYDMIKEINILIESITDKNELLSEELFTNNLSEF
                     YDESLDEIYIDLKQAYLYIKKNTDSLNIEDSIEYVFDVDISNDIKAKENPLINFNSLS
                     LVVWSGETKHILQQMNILDLEDIHSYYMENNTNITIYENNTLQYKFDEESEDIKDSSI
                     DIIEQMLILPDDLNYDKDEVENMKSRLAKINIKYLQTLKEKDIKIKLINSNLTDEPEF
                     SDLKYQLPPCWVRSGKTWKDVPGIYRNNSIVAKIGYSNPSYANVHSSKNLELHETAHA
                     IDKNVLNKKSNSEEFMEVFAQERYKLYDPKQVAHAYISKFIEEFFAESFVHYYLDEDS
                     KNTLKENCPLTYDFLEKLELNY"
     gene            71025..71336
                     /locus_tag="JAM15_00315"
     CDS             71025..71336
                     /locus_tag="JAM15_00315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HAT6796713.1"
                     /translation="MYFTYIIRCKDDSLYTGYTSNIVRRMNEHKLGINSKYTRAKGFE
                     KLEVYFVTNTKSNAMKLEYYIKKLTRNKKLSIIKNPSILINLIDNKEDYIIGKEIEQL
                     T"
     regulatory      71429..71521
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            71621..72415
                     /gene="thiD"
                     /locus_tag="JAM15_00320"
     CDS             71621..72415
                     /gene="thiD"
                     /locus_tag="JAM15_00320"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HAT6796714.1"
                     /translation="MSNYKIPTLTIAGSDSSGGAGIQADLKTFSAIGTYGMSVITAIT
                     AQNTKGVFAVEDLNKKIIKKQIEAVFEDIPPRAVKIGMVSSPEIILEIVENLKKYNPK
                     YLVVDPVMISKSGYYLLKPEAKENLIKYLIPLAYIITPNIPEAEEITGIKIHNVDDMK
                     RVGEEILQLGPKFVLMKGGHLDGEAVDILVGKNIFKVYKSERIDKKNTHGTGCTLSSA
                     ITSYLALGYEITEAVNLSKIYITEAIKRSFDIGHGVGPVHHFYKFE"
     gene            72439..73227
                     /gene="thiM"
                     /locus_tag="JAM15_00325"
     CDS             72439..73227
                     /gene="thiM"
                     /locus_tag="JAM15_00325"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HAT6796715.1"
                     /translation="MYNLIKDVKKLNPLVIHYTNNVTINDCANVTLAVGASPLMSFSY
                     EEVEEMVSVANSVVINIGTMNSNMLDLFLLAGKAANKYNKPVVLDPVGVFASKARAEL
                     TSRLLNEVKFSVVKGNVSEIKFIGGFNVRGKGVDSFDEEEDSTEIIRKIAEKLECVVV
                     ATGKIDIITNGKGTYKINNGTDKLKGITGTGCMTASLIASFMAVTENILEAATMGVLT
                     MSLSGELANLNNPPIGTFKENLMNAIYQMDIDTLSKNSNIEFLN"
     gene            73250..73882
                     /gene="thiE"
                     /locus_tag="JAM15_00330"
     CDS             73250..73882
                     /gene="thiE"
                     /locus_tag="JAM15_00330"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HAT6796716.1"
                     /translation="MIDKESLKKCLKLYLVTDSEMLRGRDFYKCLEEAISSGITTVQL
                     REKNASGREFLRKAMKLREITKRYGVKFIINDRVDIALICDADGVHVGQSDIDVREVR
                     KLIGNNKILGVSARTLEEAICAKNDGADYLGVGSIFTTSTKLDAKSASFETVKEIKEK
                     VDMPFVLIGGINLDNIDKLKCLESDGYAIISAILKAEDISKEVEKWTLKI"
     gene            74021..74323
                     /locus_tag="JAM15_00335"
     CDS             74021..74323
                     /locus_tag="JAM15_00335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAT6796717.1"
                     /translation="MIRILLVCVGSMSSTLLVNKMEKDAKKRNIDCKIWAVGEGDIKS
                     ELDNFDILLLGPQLRFMLDDVKSIVGDRAPVSIIDMVNYGTCNGHAVLNSVLEILK"
     gene            complement(74389..75144)
                     /locus_tag="JAM15_00340"
     CDS             complement(74389..75144)
                     /locus_tag="JAM15_00340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6796718.1"
                     /translation="MGMLNILWRSMKWRFKNPISFVVTILQPFLWLVLYSSIANQTMN
                     NININNYTAFILPGIIVLVVFSSCSSGGIINFIMKNSGSFYRVLIAPISRYSIVLGQL
                     LEAILVSFIEVIILCIVSIFFSVRIESGIGGILLMIVLIFMTAFFLSSLAYSISLLLP
                     NEIVYETIMTAIVLPIFFLSSALFPIESLSGGLKVAVMLNPFTHVINALRSLIFGETI
                     LIGDILPVILLFLILCCSSFSLAMWRLKKEMVS"
     gene            complement(75132..76094)
                     /locus_tag="JAM15_00345"
     CDS             complement(75132..76094)
                     /locus_tag="JAM15_00345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6796719.1"
                     /translation="MLAIEIDNLVKEYKNGVKALNGLSFNVNAGEIFSLLGPNGAGKS
                     SLINILTTFYKPTSGNVKMFGKDLVDNPSWIRTQIACVAQQISIDEHLSLMENMVFQS
                     KMYKVEPQIAKQRIDSLIDKFDLSSYLKYPTSSYSGGVKRRLDIAMNMVSSPKILFLD
                     EPTVGMDVDSRKSMWDMLLKIRDEYGTTIFLTTHYLEEAEQLSDNICIMKNGKDLAQG
                     TPSSLRSYIRQNILRITFHNTEDIKKYKDSIKSTGLVKFMSVRENSIFISVNDSRTAF
                     TLINKWLLEHDIEFDAIEIVEPSLEDVFLAFTSSKKSLKEEWEC"
     gene            complement(76098..76556)
                     /locus_tag="JAM15_00350"
     CDS             complement(76098..76556)
                     /locus_tag="JAM15_00350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HAT6796720.1"
                     /translation="MNCKIEIKNIESVTVATMRYNGPMTEATKYFPNVFKAIKGKSNG
                     APFFCYYDVDQKTGVAEMELCVPTAETPNRMGITTKEFPKTKALFFTHTGSYSNLPKT
                     YEMIFKYIHENNIKIQTPWREVFIKGPGMLIKGNPDNYITEIIFPLKEEE"
     gene            76912..77268
                     /locus_tag="JAM15_00355"
     CDS             76912..77268
                     /locus_tag="JAM15_00355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAT6796721.1"
                     /translation="MNFELDNTTPIYLQIVKYIKRQIVTGELKPGETIPSRREMALNL
                     KVNLNTVQRAYKEMGDMNIINTFKNYQSSVTVDENILKNLKLELINESLSVFIEDMKA
                     INVSKEEVLKIIEDKY"
     gene            77340..78056
                     /locus_tag="JAM15_00360"
     CDS             77340..78056
                     /locus_tag="JAM15_00360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6796722.1"
                     /translation="MIEIKNVSKTYKRMQGLKIRKIEALKNVSFNIEKGKITALLGIN
                     GVGKSTMLKAIAGLINIDSGEIRIDGEKINEKVYNKLAFVPDVQSHFSNTTIKETFEF
                     MEIFYSKWNKEKSKEMMDIFKLDEDEIIDNLSKGNIARVKLILGFCQDPEYILLDEPF
                     TGIDLFKREEFIGVIAQYMEENQAIIITTHEIVEIESLVDEVVILDEGQIITSFNAEE
                     LREREGKSILDKMREVYKNE"
     gene            78049..78873
                     /locus_tag="JAM15_00365"
     CDS             78049..78873
                     /locus_tag="JAM15_00365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6796723.1"
                     /translation="MNKLLYLINVDLRRSNKFYIAYISFFSLITLSLNLFEINKFKNS
                     KFIMNLAIEDFGGIFYGLGILSNLGFIQNILFFGMLGLFIYYIFMWKREFFSNNQSIY
                     TLMMLPQNKFKICISKSIVLITMIYGFLISQTATLFICKYIFNFIFRNIPIINMNFAK
                     DLYYLNLKSIPIDFISFMAIYVFLLLIAISIVNCCILFIFSYINKFYVILITLLIIAG
                     LYFSTIYINIINLFRKYYNLIGFQFNNLVAGLLSFLIIMFILNGISYLLIKKKVSL"
     gene            78885..80084
                     /locus_tag="JAM15_00370"
     CDS             78885..80084
                     /locus_tag="JAM15_00370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796724.1"
                     /translation="MKLKSKISILIIFLTLAIYFSIGLLNNEDNLKIKTIKGDSNELD
                     HININFGYALNGYINSYYTINGSNKTKKTELIKLQKDSKNTNNLIDVSSGSDLIAHVG
                     FEMNEESKDINFVIDEKKEDLEKGVFPSEGSDKEIEYEKLDMNNFTRTRYKVDKSTDD
                     YYANILASKRYKKYLYVSVLYATSDSSENNKEYSSTIDIIKINPENKKIKTIKSINLS
                     NYFSEKYQDIENIGVSYASKYEDKMYILVNVLNTNIGDNSNSKFHLLEYNLEENKESI
                     MELKTDSKMALAKAKLEANKLYMVMSNDYDNSSITELNLLTYNILDKSLDEDKYVLDN
                     REKRGIRSIEIDSNKIVAYTSRLNSILSWDNKFMLYIINKNSKEIVYEGELQFNSSNS
                     MLEFEIK"
     gene            80093..80905
                     /locus_tag="JAM15_00375"
     CDS             80093..80905
                     /locus_tag="JAM15_00375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796725.1"
                     /translation="MKDLIRLFEFELKRNIKNYIFIIICCCSFVILNIVKNLNDYNYI
                     IENAVKSEQLTKIGNTIETVNVTGFSSFRNIMGSTESWFMFGIIACICYAFFIWYRDF
                     NGRSKSIYTLIMLPKNRINIYISKLLNILFLVYSYTVVLTISLFIASKLLPRHMLGNV
                     TNYGFVQETIYELKMLLPYSFEILFVEYIFLLIGFVSVVFTSILINKSIYKVSTLISF
                     LFLVLEILVFIISIEFIIPYEYSDVFTVLYSSINIFVCSLISNKLLKQKIDF"
     gene            80916..82184
                     /locus_tag="JAM15_00380"
     CDS             80916..82184
                     /locus_tag="JAM15_00380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796726.1"
                     /translation="MKAKNIGKYTICFIIVCFLMITMTLILSYFNKDKLSVKTLKGNV
                     KDIGRVSVVYTPNISKFSYEEVIISKNGVRNNKNPKSRIRNDYLNIDKKYSDFVNDKG
                     KELIYKDDLNIGEAYTSVKSDLVQGMNALNDCIKVSNKNLKSGVEENFDINLNKSDFK
                     ENSWKTLFNKIYKGNLYMVISETNISGSKVNNICILKIDIKNKSYKLLNRFNLGLQNG
                     YQQNINEIKFSIGSKLYLEIVNNKSKNGDIEGHDSYSNLIIYDIEDNTFNISNKFMDN
                     LNKEKNANPKEIGLLSKTKLDYMIKNNKLNLIVTDMSNSIINLVYDINSNEIKLEDYE
                     ILDLKVDYNEASSGVRKAKLLDDKIYSISGMKNSISGELKGFKGIVDVVGTKPVKFQV
                     FDMKLKKNIYEAELINGDISLQEKLFFVAN"
     gene            82550..83731
                     /locus_tag="JAM15_00385"
     CDS             82550..83731
                     /locus_tag="JAM15_00385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HAT6796727.1"
                     /translation="MNKKYIKAGNLIDGTGNSIMQNKGIIIDGDTIVEIEDIRDDLNG
                     YDVYDYLDKTVMPGIMNCHVHLTMEPVGNPKIYYDNVSDVELVVNTIKQLDAYLDSGV
                     TYIRSLGCPKYVDVQLKNLIDKGSIDGPGIVTSGPVICMTGGHGYYFGIESDGVDECR
                     KSARTVLKNGVDCVKIMATGGVTTDGVEPGSPQLTLEEMKAAVDEAIKAGKITATHAQ
                     GRTGIKNAVLAGITSIEHGVYLDDEIIDLMLERGTYLVPTVAAPYFILNAGKESGITE
                     ATLRKCEIVAIPHKESFLKAYKKGIKIAVGSDAGTSYNEHGKTYYEMKLMSDYGMDNM
                     DIIVAATKTASELLRIDKNYGTLEKGKKADVIVVNGNPVENIDVLADVLAVFKLGKKV
                     R"
     gene            complement(83873..84790)
                     /locus_tag="JAM15_00390"
     CDS             complement(83873..84790)
                     /locus_tag="JAM15_00390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796728.1"
                     /translation="MENNKCREDFRFTQEYEEDYPNTNERYYENYQVADRYYNYPNKY
                     KEPKIKQCCCKKSMREALELLRYDALRPFVNFNQFAFISDFFIVGANLVGIDLSAPPK
                     DNLSGLDGTFERFSACNCDLIDIAGRVSYPIPVPLTLEGLINTIGTIPGVAELIALID
                     AVIPPTIDLGAILDAILAAIIDFILAASTPLANVDLASLCNLKAVAFDITPADYEDFI
                     ASLGYYLDKKHYKECNCNCDCDDCCCNKGILDNLYMSNINNQVTVVAGSLVLTGVEVL
                     GKKNDVIVLGNSNDSRIYFVCVDSIDYIA"
     gene            85043..85837
                     /locus_tag="JAM15_00395"
     CDS             85043..85837
                     /locus_tag="JAM15_00395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6796729.1"
                     /translation="MIEVDKLCKSFTRVVKDDKNKSSIRKLKKVKTKKEEFFAVNNVS
                     FKVMEGEIVGILGPNGAGKTTLLRMLGGILTPTSGSINISGYDYSIDRNSAKKEIGYL
                     SGNTKLYGRLSPRELLTTFASLYEMSKEDIEESIENIVKIMDMSEFIDNRIENLSTGQ
                     TQRTSIARCLIHSPKVYIFDEPTLGLDVLSSASIIDFMKNEKLRGKTVLYSTHYMEEA
                     ETLCDKIFMIHNGKIIASGTPQSLKEESGVNNLRDVFIKLARKEDI"
     gene            85838..87898
                     /locus_tag="JAM15_00400"
     CDS             85838..87898
                     /locus_tag="JAM15_00400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAT6796730.1"
                     /translation="MRSKIVKYIFKKEMLDILRDKKTLFMMIVVPLLLYPLLMLLMIQ
                     VMNMSASSMNSKDINIAFNNKPNKVLVSMIEDDNLEKDTKNTSNDKGKIRVLDVDNYK
                     KSLEENKIDAYIKMEEKKSSINYQIYINSSQENSSNALKRIETVLDKYKRFTIEKTLS
                     EKGLDVQATLEPITYSTVDVAKTEEVAGYFLGQILPFILIIGVLLGSIYPAIDVMAGE
                     KERGTLETLFTLPISNLELVMGKYMAVSLSAIVTAILNILSMGLTMAFILVSGGISSQ
                     FGFGNFNYGDLVLPIITTLICICLFSMVVSAISMCVCSLAKSFKDAQNYITPLMLIIM
                     IPSYVSMIPNIVLDRVTAVIPVVNISLLIKSVLSFKSDLNLIALVLASNVAFVILAII
                     LLSKMFNSEEILFGNSKSFSFLEKRSNIKKGSIPTVSDGVILYAVGLVLLIYVGSLVQ
                     IKFGMAGIIMTQFMIISLPLLFACYIKADFKEVFSLKIPKLKHVFGSIVLWIGGYILI
                     MIITQLILFLFPQNMEVAESLNKALFIKDSVLLNLLVIALLPAICEEMFFRGFIFSSF
                     SKSKDKNKSIKLAIICSGVLFGIMHMDFIRIIPTSILGIIFAYSVYKSGSIFVSMLLH
                     FLNNSVAVVLNHYTTGNITNLYKFVEVDFSNLNVLKFALILLISLILIMLGLRVLDRK
                     SLRN"
     gene            88580..90124
                     /locus_tag="JAM15_00405"
     CDS             88580..90124
                     /locus_tag="JAM15_00405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HAT6796731.1"
                     /translation="MRNLQKKLMFFLFICIILQITYTTPVYSLCKLYKNNSINNFESI
                     VSNNQFISKYAIQIILIMAIICMMLIFYIIYDKLNFKIKLQKIAYTDNLTGANTIDKF
                     VIDANKILCKNTQVKYALLYIDIDKFKYINDLFGYEVGNEILRNLTKIIKSNIFEEEM
                     FARISADNFIIIMKYIEEEDITKRLKTIFEELDLFNNNQEEKYKLVLSCGIYFILPED
                     RDINSIIDRANIPHKMAKGGHKSSYAFYDNKIHDQEIKEKEMENTMFSSLENKEFIIY
                     LQPKIELNTGEIQGSEALVRWKRPDKGLIPPNEFIPFFERNGFVINLDLYVLEEVCIY
                     LRKWIDAGINPVTVSVNVSRIHLYCNNFIETYKNIIDKYNIPAKYIELELTESIIFDN
                     FDILIDIMNNLKKIGFLISMDDFGSGYSSLNMLKEIPMDILKLDQKFIMETYNSKRSK
                     IIVTKVIEMAKELGMKVISEGVETEEQFELLKEVKCDMAQGYLFGKPMPIEEFEHLIV
                     SNLVRG"
     gene            90300..90668
                     /locus_tag="JAM15_00410"
     CDS             90300..90668
                     /locus_tag="JAM15_00410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAT6796732.1"
                     /translation="MEWELDNNKPIYIQLVEHLKLKIISGEIKIGSKLETVRALAEDA
                     EVNPNTMQKALTELERQGLVYSQRTKGRFVTDDKEKIKAMKEEIANVEINTLKVTLEK
                     LGYDRDEMLKLITENLKGEL"
     gene            90670..91395
                     /locus_tag="JAM15_00415"
     CDS             90670..91395
                     /locus_tag="JAM15_00415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6796733.1"
                     /translation="MDKNINNVSQDGIVEFKGVNKSYGTKNVLKNIDLNIPKGKIVGL
                     LGPNGSGKSTMIKLMNGLLQPDNGEIMINGMKPSIDTKKIVSYLPERTYLNDWMKVSD
                     LLKFFYDFYSDFDVRRANEMIKSLDIDVNEKLKTMSKGTKEKVQLILVMSRNASIYIL
                     DEPIGGVDPAARSYILKTILKNYSEDSTLLIATHLISEIENICDEIIFISKGEIVLQG
                     DVEAIREEKGKSIDALFREEFKC"
     gene            91389..92153
                     /locus_tag="JAM15_00420"
     CDS             91389..92153
                     /locus_tag="JAM15_00420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6796734.1"
                     /translation="MLGKLLKYELKASGRIFIPLYIAILIVAVFNGIFMNTNILQVQG
                     IGILVLTSLFMALGVLTIVVTIQRFRKNLLGDEGYLMFTLPVSTSSLILSKCITALIY
                     AVLSFIVAVFTFGVLMLFGTSGILLPEILDLFNTSFKWISENFLDILLLLVVMFISYS
                     SFILLLYTSISMGQLPKFNKHRNIVAFASFIAINIVISIVGDAVGSILPNEDTNMVYH
                     LHQSPSFMLAILGSLVVAIALFFATKFILDKKLNLE"
     gene            92375..93625
                     /locus_tag="JAM15_00425"
     CDS             92375..93625
                     /locus_tag="JAM15_00425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAT6796735.1"
                     /translation="MKSYTKAKWSVWGIITFSFVLVLFLRMSTAVVSDNLANELGFNS
                     IQISNIASFCLYAYAFMQIPAGILIDKYGARKISSLGIIMASLGSILFGLIQSIELAY
                     ISRVIVGAGTSVILLCILKIQGRWFNKSEFASATAKFSFVGNLGGVLATFPLVFLSEL
                     VGWRNSFLLIGIIGVVIGCFIYIIVRDTPKEYGFNVDTEPYEKSEKVNIVDGIKSVIK
                     NKSTWYNSMIMFSFVGLTSAFISLWGVRYIMDVYGVSKSFSAFIVSFFTYGFIFGSII
                     MDFVFAKIRSSKFNIIKFGAMIDLFIWIVIVVVYQVKPPIIVLPISFFIMGCIVMSHL
                     QVFNDAKYKNKEIYSGLATSVINTFEFIGSGIINLIIAISLQVNSYNIVDGYKKGFVV
                     FIVLSIITIVSSHIGVKNDDCKAI"
     gene            93816..94700
                     /locus_tag="JAM15_00430"
     CDS             93816..94700
                     /locus_tag="JAM15_00430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HAT6796736.1"
                     /translation="MDTTKIDDISKLDLNNLDINKMDMGGIMESLLEWATTSGVKLII
                     GILILSIGFKIIKKFVNHVMLVLSKRDIDLTLRRFLKSLLLSVLKVAVIIIVLEYWGM
                     SLSSFAAVIASAGVAIGLALQGSLSNFAGGFIILLIRPFKVGDYVEAAGHGGTVEQIG
                     LFYTQLVTPDNKQILIPNGSVSNDSLINYSAKNTRRVDLTFSVGYEDDILHVRRVLKD
                     IVNNHKLIINEPEPFIGVVEHGDNAVKFATRVWCKTEDYWTIYLDLLEEVKVRFDEEG
                     ITIPYPKMDLTVKELNKI"
     gene            95062..95679
                     /locus_tag="JAM15_00435"
     CDS             95062..95679
                     /locus_tag="JAM15_00435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796737.1"
                     /translation="MCKKTYLLVVSILIAGLLTACSGSPTKDSGQAQDNTKKEANASN
                     NALKDEKNNENLMEQDFKVPYTDAINIFKDKYKDADIVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTEKLDSEDLNGVARKEKLDLNDIITPQQAMEIALKEQNG
                     MVKEWSLDKDLDVTFYKIRIDKDKNEYDIKVDSKKGTVLKVEKED"
     gene            95787..98318
                     /locus_tag="JAM15_00440"
     CDS             95787..98318
                     /locus_tag="JAM15_00440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAT6796738.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIKE
                     DKTLVTCDSFGSHYSNDKIVNTLDENEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVKEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKPIWDILISL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNEEIDKLHSY
                     TGKFLDKLNSTFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFIEVEEDEVT
                     FRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVV
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVFKDGDSVDC
                     DMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNVKDIYACGDVAQVGNIGLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFDDIMKADIL"
     gene            98752..99453
                     /locus_tag="JAM15_00445"
     CDS             98752..99453
                     /locus_tag="JAM15_00445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanG-Cd-type vancomycin resistance DNA-binding
                     response regulator VanS"
                     /protein_id="HAT6796739.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KNLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            99503..100585
                     /locus_tag="JAM15_00450"
     CDS             99503..100585
                     /locus_tag="JAM15_00450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAT6796740.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGMDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFINRSNTIPEEKLERIFEQFYRLDISRNSNSGRAGVGLAIAKEIVEL
                     HNGTITAHSENNIITFKVIIPIVGNL"
     gene            100846..101946
                     /locus_tag="JAM15_00455"
     CDS             100846..101946
                     /locus_tag="JAM15_00455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HAT6796741.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDILPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLISDAVSQNHIPNS
                     AIESCENNIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKIPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNDDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            101943..102749
                     /locus_tag="JAM15_00460"
     CDS             101943..102749
                     /locus_tag="JAM15_00460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HAT6796742.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRIFIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            102767..104905
                     /gene="vanT"
                     /locus_tag="JAM15_00465"
     CDS             102767..104905
                     /gene="vanT"
                     /locus_tag="JAM15_00465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HAT6796743.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYNKMADFVLTSII
                     ARIAVPFFFMLSGFFLISKYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKKLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYVFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGPRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKD
                     LKGEQKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCKLMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSSPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSASEVANNSCSISNELLSRVGRRLNVIKK"
     gene            105219..105839
                     /locus_tag="JAM15_00470"
     CDS             105219..105839
                     /locus_tag="JAM15_00470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAT6796744.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHHNDKDDKMI"
     gene            complement(106005..106541)
                     /locus_tag="JAM15_00475"
     CDS             complement(106005..106541)
                     /locus_tag="JAM15_00475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HAT6796745.1"
                     /translation="MIKETHERGGYIFALLILPFINNLYLVKYDIAYKIVLIIIYIYF
                     AYLGSLFPDIDMRGSYISKKFMLIYKLFGSRFRHRGFTHSLIALLLIYSFFKSLTIFT
                     NNNIVFSCLSSGFIIGYLSHLCLDLITKEGIELFYPITINISLLPIKTNSKTEKFISK
                     LLNFIVIFLIGYQFYILL"
     gene            complement(106654..107358)
                     /locus_tag="JAM15_00480"
     CDS             complement(106654..107358)
                     /locus_tag="JAM15_00480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HAT6796746.1"
                     /translation="MKKKILIPVIMSLFIISQCITSFAFTPENNKFKVKPLPYAYDAL
                     EPYIDKETMKLHHDKHYQAYVDKLNAALEKYPELYNYSLCELLQNLDSLPKDIATTVR
                     NNAGGAYNHKFFFDIMTPEKTIPSESLKEAIDRDFGSFEKFKQEFQKSALDVFGSGWA
                     WLVATKDGKLSIMTTPNQDSPVSKNLTPIIGLDVWEHAYYLKYQNRRNEYIGNWFNVV
                     NWNGALENYKNLKSQD"
     gene            107530..109404
                     /gene="asnB"
                     /locus_tag="JAM15_00485"
     CDS             107530..109404
                     /gene="asnB"
                     /locus_tag="JAM15_00485"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HAT6796747.1"
                     /translation="MDGNISIYYKGDISKKENIKFKIKESVNNTRLSSRIEYKDEEKT
                     FDFERFNVIDAIYGNKPFEKDGKVIVFNGNIYNYHEIKEELIKKGHNFTTNDDIEVLL
                     ASYIEFGKNCVHKIKGMFNFIIYDRENESIFGARDLFGIKPLYYINKENAIIFSSEYK
                     FLLEYMKNLNINERSLQSYFSFQYVLPEDTMIQGIRLIPAGHYFRVENGILSLKRYNK
                     LEFRSSTKFFYTKNHLGNRDVNEDDIRNIVVDSIVTHMEEEKEIGTFLSGGIDSSIIT
                     TVASQINPNIKSFSAGFSVKGYSELEVAKKTADKLGIENIQINITQDEYIKSLPDVIY
                     SLDDPIADPSEVGLYFLIKEAGKHVKVALSGEGADELFGGYNIYKEYSTMKSVVNSPT
                     YIKSILGRVSELMPNIKGRNYLYRATTPLEKRYIGNAKVFENSEVKRFFFKYKEKNIY
                     EYLLSNLYRDAQKNNYDYISKMQHIDVNTWLQGDILQKISKLSTAEQVELRVPFLYKD
                     VFDVAKNLRMEQKINKNNTKVLLREAFREIVPEHVVQRKKLGFPTPIRVWLKDSLGDI
                     VKETIYNSNVDEFIDKKYAIKLLDMHLKGHRDNSRKIWTIFTFCLWHQLFIEHKNVEY
                     "
     gene            complement(109496..110932)
                     /locus_tag="JAM15_00490"
     CDS             complement(109496..110932)
                     /locus_tag="JAM15_00490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like serine protease"
                     /protein_id="HAT6796748.1"
                     /translation="MICTIKPLKISIKKSTEPLIEFISDTTYKNKSSSYIKEVYFTRY
                     IGVDDSIDKYIEKIKNIDTYFFNNPTIPYIRLNNLKINFDKEQTDKMLKIFNIYDSSK
                     FNSWDLYNIDFPCKIENDTLNWTKKIAFKNTLDLFSTSMPNCTSSIIKNFAVKLLCWM
                     DYFLPKLFYNKVKTTISPKIVYFGNIKRQELFFLYFLSQLGCDILYINPNKDILDLYP
                     ECSKFSTLFELSRKTPNILETPFERHITNINYSENTNKTSPTTNKPNSKNTLNNTNLT
                     SKKIAQDEEVELSYEDLAKLSASVVMIVVCNNENKPFKSGSGVVINNEGYILTNLHVV
                     NDGYSFLVRFENDDKVYTSYQIIKYHSDYDLAVIKVDRKCKPIPVKVSKKPVRGQKIV
                     AIGSPLGLFNTVSDGIISAFRDFETVQMIQFTAPISSGSSGGALLDMFGNLLGLISAG
                     YDDGQNLNLAVESNLVKIFANNFIEIVN"
     gene            111261..111839
                     /locus_tag="JAM15_00495"
     CDS             111261..111839
                     /locus_tag="JAM15_00495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013726569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HAT6796749.1"
                     /translation="MGITLSKGQKVDLTKGNPGLKNILVGLGWDTNKYDGGFDFDLDT
                     AAFLTGASGSVTNDGDFVFYNNLKHTSGAVEHLGDNRTGEGDGDDEQIVVDLSKIPGE
                     ISKISFTVTIHDATERRQNFGQVSNSYIRIVDKDTNEELIKYELGEDFSIETAIVVAE
                     IYKHNGEWKFNALGSGFEGGLAALCGNFGINL"
     gene            111878..112456
                     /locus_tag="JAM15_00500"
     CDS             111878..112456
                     /locus_tag="JAM15_00500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009527653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HAT6796750.1"
                     /translation="MAIVLKKGQKIDLTKGNPGLKNIKLGLGWDTNSFDSGYDYDLDV
                     SVFMVGESQRVEKDEDFIFYNNLKHPSGAVEHLGDNRTGEGDGDDEEILVNLEAIPKH
                     IQKIAVTVTIYEAAERRQNFGQVSNSYIRVLNSENDEEILRYDLGEEFSIETAITVCE
                     IYKYNGEWKFSAVGAGFEGGLEALCRNYGLNV"
     gene            112542..113171
                     /locus_tag="JAM15_00505"
     CDS             112542..113171
                     /locus_tag="JAM15_00505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HAT6796751.1"
                     /translation="MSINLSKGDKIDLKKSNPGLSNILVGLGWDPVQQSGGGFFKSLF
                     GGGQADIDCDASVFMLNQEGKLSGIKDLIYFGNLKSACKSVLHTGDNLTGEGTGDDEQ
                     ILVNLDKVPSNIHKLLFVVNIYNCVDRKQHFGMIENAYIRVEDQGNKKEIAKYNLSDN
                     YSEKTTLIVGAIYRKDGSWQFKAIGEGTKDAGLKEVMQNLDRIECAYGI"
     gene            113161..115920
                     /locus_tag="JAM15_00510"
     CDS             113161..115920
                     /locus_tag="JAM15_00510"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HAT6796752.1"
                     /translation="MEFNNDIKYYNVDKEEVTKDLSVNPEKGLSESEVKTRREKYGLN
                     EFTPKEEGSFWDDLKESLSEPMIVILIIAAVVSAVIGETHDAIGIVGAIAIGIAIGMI
                     TEGRSKKAAEALSKLTENIEVKVLRDGEVHQISKSELVPGDIVYIETGDMVPADGRLI
                     ESINLKIREDMLTGESDDVSKKCDVVVSMEEIESKGAVVVQEPIPAKQINMVFGGTLV
                     AYGRGALVVTSIGDNSEMGKIAQNLSETDEQTPLQIKLGNLGGLIAKVSSAVAGLLFI
                     FMVFQMISKNVLNVDMSGILPFLESIDPVKTAFTVCVALIVAAVPEGLPTMINMTLAI
                     TMQKMAKINALVTKKEACETIGSVSVICSDKTGTLTENRMTVEVAYVDGRYIESSEEE
                     INSYFEENCMINSTADVEHNDGDIKYLGSATECALLLYYKNVDYRQVRKNSNIVAQNP
                     FTSDSKRMTSVIGQDNHHVLLSKGAPEVLLELCSHIQRGKDIVPLTENIKHEILEEIK
                     KLQIKSMRTLGFAYKEISQAEEEAAVTAESDAMNVSAMENNLVFSGFVGIRDPLRKDV
                     IESVNTANKAGVSVKMLTGDNINTARAIGEELGLLKNNMRVVEASYIDTLDDEELKQE
                     IQSISIVARSKPDSKMRIVSALQKSGDVVAVTGDGINDAPALSKADVGIAMGISGTEV
                     SKNAADIILTDDSFSTIVKGIKWGRGIYDNFQRFVQFQLTVNVIAFLVAIISQVMGQE
                     MPFTTIQLLWVNIIMDGPPALALGLEPVRDHVLNRKPVDRKANIISKSMVYTIVLNAF
                     YITAILMLQSTFNFLGVDEAHKGTVMFALFAFSALFNAFNCREFNADSIFPNFTHNKL
                     ALQIIVLTGIAQVIFTQLFQDFFNSVAMDFMTWVKVLCVAASVIVVNEVVKCIIRLVK
                     PKKTA"
     gene            116007..117569
                     /locus_tag="JAM15_00515"
     CDS             116007..117569
                     /locus_tag="JAM15_00515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796753.1"
                     /translation="MGDSKVFEKIFSSQSDRGNYTPSKGYLSYFISYIGLEDEVLYNL
                     EIFKTKQNIDSKKDIALFTDVIANPSDFDIINYFKSGLQKYRTSMEDVDINILGFEEI
                     DYKIKQAMDRVLKEEEKEFTNDRVKQNFIVKIMAWIKIYIGALDINKNEAPKVIFYGD
                     IKKHEVYLLLILYLAGFDVLYLNPNSKSNIDILKSERYNIEFEEANIIEEKISFEERV
                     ILGEKIDKSSVKKAFTVGAEASKRISEELLNDAGFIKPWQLQDRKIKNLLLSSTVDEI
                     SIYWNQPLKLRPGFKFNDAIVEAPNFLSKINGIYNDKNEYIKFLDLLRDSESSTFIEF
                     NGDVDRFSKAFTREAFSLSFLLDSKGVIDKNSVLNNKDYSISTLALNQQIMILEKVEE
                     LLEGSMFLNGLSGEDKIKGLFTVLHMDKKFVHMMNNFDYSLINPKLIIYMYKSIVFDK
                     EIVFLMLLLSKIGFDIIILCPGGESNIENVINNQLIDIHRLDKMVYDLKLNSLENDIP
                     LLKKIFGKRRRF"
     gene            117570..118706
                     /locus_tag="JAM15_00520"
     CDS             117570..118706
                     /locus_tag="JAM15_00520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HAT6796754.1"
                     /translation="MGININSFSKDKNSVEVTENLPTAVQEENFDIMEYTNNKKNELR
                     KSKEVEALTSLIEVENPDTILQFGRKASEGVARVSDSLLNTIKLNRNEENSKMLVHLT
                     KIMDKFDLDDFQETKEPNFVQKLFKKANNAIEMMFQKYETLGGEVEKIQIELEQYERD
                     IALSNKQIGAMLNENFEFYNELQKYIVAGEMAIEEMDNEILPFFKQKSETSGDQMDVV
                     NYQELLKVYDMLNQRVYDLRIAENIAIQTIPMLRGMQHNNYGLIRKINSAFVVTLPVF
                     KQCLSQAILLKKQELQAKSLKALDDKTNELLLRNAQNVSTQSAQIARMAGTSSVQIET
                     LEKMYNTIKSGIDETMRIEENNRALIKDNTKRLEELNTTIIYNK"
     gene            118770..119846
                     /locus_tag="JAM15_00525"
     CDS             118770..119846
                     /locus_tag="JAM15_00525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HpcH/HpaI aldolase/citrate lyase family protein"
                     /protein_id="HAT6796755.1"
                     /translation="MKYFDYICKDDLERIFLKEPEDFSAKTEKDVLKYALGAFLYVPA
                     TQYNMIYKSIIGDVKGVRPLAICLEDAVGVNGELEAIENLRLILKNISNESITNKDGI
                     PLIFVRIKDVEQLLRIKEIIIKNRHSITGILIPKANSELIENCIEALDSMNLQDMYVI
                     PIIETREFIYNEKKELSFTNLYNAILRHKSRILSIRVGITDILGMYGIRRDKNFSIYN
                     NLICSSFILDIITYLQRPELDIPISGGVSEFFDMTNKDIRNKYIEEILLDKYHGLIGK
                     TVIHPMQIQIVQALSTVSYEDFTDALDILDSTDSKYGVSKGVLGERMNETNPHFLWAK
                     KTLILSKIYGVLNKGVDYEELLKF"
     gene            119824..121062
                     /locus_tag="JAM15_00530"
     CDS             119824..121062
                     /locus_tag="JAM15_00530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796756.1"
                     /translation="MKNCLNFNCEIDIIDNPLNLELNDFLDVGIRNNSKRRFLFISKK
                     LGKHLACKPSEMDNLGKLMATIYNEKNKEESNGTVIAFAETGTAVGHSFFDYLCGDYE
                     FIHTTREQFDELENLEFLEEHSHATDQNLYFGMLNNFKFGDEIILVDDEITTANTCMN
                     IIRKIQSIYPKKKYTICSILNWVSDENLSKVTRLERELNCKIDFVYLFKGNFKFYIDE
                     DIISNYNDNYSITKLETISSDKVNLVVNHIYVDLEDYIGNKKYVKYTGRFGINRREQF
                     RLKEIVKRESKKITMASKESLKNEKEKILFLGTEEFMYIPMLFAKEKENQYDIYYHST
                     TRSPIINIDKKHYPIKSKFMLKSFYNIDIQNYIYNIDKHNFSKCYLFVELNKSENSYL
                     EFIDIIKKTSIKELTIVCCS"
     gene            121116..122204
                     /locus_tag="JAM15_00535"
     CDS             121116..122204
                     /locus_tag="JAM15_00535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine protease StiP family protein"
                     /protein_id="HAT6796757.1"
                     /translation="MRDFSTYSKDDVIFLLKDISNLIEEEGNKERELKIQNGRHYSEM
                     IPIEYEVSEDYLNLYHEKLRENKDKLAFSIGVMCEKIIKKNGNDVVLVSLARAGTPIG
                     ILAKRYIRSKYNVSLPHYTISIIRDKGIDMNAIEYIVKNHPSSKIQFLDGWTGKGTIS
                     KELEKACDELNVKFKKHFDSTLAVLADPAGYSGLYGIREDFLIPSACLNSTVSGLVSR
                     TVLREDLIGKNDFHGAKFYRHLKDKDESMNYIETIEECFKNQFKNISDEVENWESDII
                     TRDGYFDVLNIKEKYNITDINFIKPGVGETTRVLLRRVPYKILVKDLNDKSLDHIFIL
                     AKEKNVEVEQMDLKAYKCCGIIKNMKDI"
     gene            122232..123023
                     /locus_tag="JAM15_00540"
     CDS             122232..123023
                     /locus_tag="JAM15_00540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HAT6796758.1"
                     /translation="MIVFSDLDRSIIYSNKFLNADSKYANIEIYREKEISYISLDTIN
                     LIKQIQYYGMFIPITTRTVEQFKRIEFNKYGIYFPWSITSNGGVILKDNEILKSWSEK
                     IDKLKSDYEPIESMIHKFKDYLNVDGITNFKVAEDTFFYIVVDFSRFNLDSIKEYTNI
                     LESKNWKFYVSGRKIYFIPKEISKENAIKYLTKELGIEYFYTVGDSIMDYGMLNISNK
                     SYVLKHGDINKNEIENSFISSSFNGMSGTEEILSNILDENCLLNI"
     gene            complement(123138..123692)
                     /locus_tag="JAM15_00545"
     CDS             complement(123138..123692)
                     /locus_tag="JAM15_00545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HAT6796759.1"
                     /translation="MNIDVGSKIRSLRKSKNISISTLAKNSDLSTGLISQIERNMVVP
                     SIVAMWKISKALDINIGYFFEEIGREDSDIIVKKNNRKKIVTNDSTKFYELLVPNLSG
                     KKIEFILVTLDGHTQKNSEFVTHEGEECGYIIKGKMKITLGNKEYLLEEGDSFYFNST
                     IPHVYENYDDEVCISVWAMTPPSF"
     gene            123887..125089
                     /locus_tag="JAM15_00550"
     CDS             123887..125089
                     /locus_tag="JAM15_00550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 domain-containing protein"
                     /protein_id="HAT6796760.1"
                     /translation="MKSFVSPDNIWVLWAVVTGWAAFSIYLEQKYNWASKVSGAIIAL
                     VGAMLLSNLNIIPVESVVYDQVWGYVVPLAIALLLYQCNIKKIWKESGRLLIIFLVGS
                     VGTVLGAMIGFLALKNVVPDLNIVAAMMTGSYIGGNVNFAAMSGAFDAPGELVSATVV
                     ADNLLMALYFFVLIAIPSIGFFRKHFKHPHVDEMESIGITEGETVAANYWGRKEISLK
                     DIAIAIGSAFIIVAVSVELSTWFKAIIPLSNPFLAMLNTLFGNQYLIITTLTMLFATF
                     MPNFFGDIKGAQELGTFLIYIFFVVVGVPASITLIIQKSPLLLLYCGIMVLINMLVTF
                     IVAKIFKFSLEEAILASNANIGGPTTAAAMAISKGWSKLVGPILIVGTFGYIVGNYFG
                     LLVGNILI"
     gene            125165..126145
                     /locus_tag="JAM15_00555"
     CDS             125165..126145
                     /locus_tag="JAM15_00555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane dipeptidase"
                     /protein_id="HAT6796761.1"
                     /translation="MIFDGHSDTWADVTIRRLNGEKDVFRRIHLDNFKRANIEGAIFV
                     IWIDPPYDKEPEKRVKQIISSIKDEIEDMKDVVNIVKKYSDIDKGISENKINILIGLE
                     GLSHIGRNIDLLDYFYKEVGARHASLTWNEQNELATGCLGDENRGLTEIGKKAVNKME
                     KLGMIVDVSHLNEKSFWDLMSVASKPVIASHSNARSLCDAKRNLTDNQLKEISNTGGL
                     VGINSFRGFTNSNPKKQDLIHLVDHIDYMVNLIGIEHVSFGFDFSDYLGKETIGSFTG
                     NASVPSVDGLESTHTAQNIVVELENRGYKKKDIDLISSGNFYRLFKDILK"
     gene            126398..127351
                     /locus_tag="JAM15_00560"
     CDS             126398..127351
                     /locus_tag="JAM15_00560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HAT6796762.1"
                     /translation="MKKRYLVIGIIILSYFSLFIGAEDINIMHIFAKNQHKLMIFIMS
                     RVPRLISILIAGVGMSIAGLIMQQISKNKFVSPTTGATIDAAQFGIVICMLLVPTASI
                     FTKTIIAFVFSLVGTFTFMKIIGKLQFKNIIFVPLVGIMFGNIIGSMTDFIAYKYDLS
                     QNVSSWMQGDFSMILKGNYEILYITIPLIILAYIYANKFTVVGMGMDFATNLGLSYKR
                     IVNIGLIIVALVTVCVVVTAGNIPFIGLIVPNIVSLYMGDNIRASIWYTGLLGAVFVL
                     ICDIFGRIIIYPYEISIGLTVGVIGSILFLYLILRRNVNEA"
     gene            127341..128297
                     /locus_tag="JAM15_00565"
     CDS             127341..128297
                     /locus_tag="JAM15_00565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HAT6796763.1"
                     /translation="MKLSLNQKIYFVSILLFISIALFIIYGIDMNHLEYALSQRIPKI
                     FAMVLGGGCIAFTTVVFQTITNNQILTPSVLGLDSLYVMIQTIIVFIFGSSSSLIINE
                     NYNFIINVAMMIGASLLLYKMLFEKNKSNIFFLILVGMIFGTLFKSATTFIQVMIDPN
                     EFLALQTSIMASLNNINTNVLLIAFIIIIAIIPFIYDEIKYLDVLSLGKEQAINLGVD
                     FDKAVKKMIILIAILVSISTALIGPMTFLGLLLANITREIFKTYKHTYLISGSMLIGM
                     ITLIIGQFFIQHVFKFDTTLSVVINFIGGIYFIQLLLKGANR"
     gene            128294..129049
                     /locus_tag="JAM15_00570"
     CDS             128294..129049
                     /locus_tag="JAM15_00570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006679308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAT6796764.1"
                     /translation="MIEIKNIFKRYKNKNVVDDVSFSIEKGKITSFIGPNGAGKSTVL
                     SIVTRLIGGDGGEVIIEGKSLTNYSNKELAKKIAILKQSNNITLKLTIRELVGFGRFP
                     YSEGNLTKEDENYIDEAIEYMKLTDIQHKYLDELSGGQRQRAYIAMVIAQDTEYILLD
                     EPLNNLDMNHSVQMMKVLRGLCDELDKTIVLVMHDINFASCYSDNIVALKNGKVEKVG
                     RTDEIVNEKVLEDIYEMNFNIKNINGNRICIYF"
     gene            129141..130106
                     /locus_tag="JAM15_00575"
     CDS             129141..130106
                     /locus_tag="JAM15_00575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HAT6796765.1"
                     /translation="MNKKAAIVAAVAIIGLVTVFALGGSKKNESKTSENSNNTIKITH
                     NLGETDVKLNPKKVVVFDYSALDTMDALGVAENLVGLPKASLPASLEKYKDKKYADLG
                     GLKEPDLEGIKSANPDLIIINGRQEDFYEQLSKIAPTISTSKDDKKYLESVKNNIDKI
                     AKIFGVEEKANQEFSKIEKKIETLNKKVTDKNLNALTIMVNEGNLSVFGEESRFSILY
                     NSFGFENKDKNIKESSHGQNITFEYIAKQNPEVMFVIDRGIATGSDVKESSTAKSVLN
                     NDIIKSMDAYKNDNIIYLDSPTWYVNDGGLASLNKMIDDASKAVN"
BASE COUNT        51235 a        13223 c        22447 g        43383 t
ORIGIN      
        1 tattgaaaat tttagatata taataaaata agagtatatt ttatataata tgaaagctgg
       61 tattgcaata gattaaagcc ttatacacgt ttagttttta aagaaattag tgttattatg
      121 aaaacctaag ttaatttatt aaataaataa ttgaataaaa aaattttatt atgtatttat
      181 aaaatttttg ttacaaattt ggcataatat agtatacttt aagtgtgtat taggttaaat
      241 ctataacaaa ttagacgtat gatatagact tagtgtttat tggcatttac aagaaatttg
      301 ttaatatcaa ctatttgtag tttgggcagt tataattatt atagggggga tgtccaatac
      361 aaaacaatca accaagaact aatattatat tataaagagt tatagttttg tgtgtttatg
      421 tttttaatta aatttaaagt gggaaaaata tatttgttag aatggagaat agcgagatga
      481 gtaataaaat agttagtaag agacaattaa cagatagtat ttatttaatg gaaatagagg
      541 cacctagagt tgcaaaatct tctcaaccag gtcaatttat aataattaaa aatgatgaaa
      601 aaggagagag gattcctctt acaatagctg actatgatag agaaaaagga acagtaacta
      661 ttgtattcca aacagttggt gcttcaacta aaaagttagc aatgtttgaa gaaaacgatt
      721 ttgtaatgga ttttgtaggg ccattaggac aagcaagtga atttatacat gaagatatag
      781 aagaattaag aaataaaaag atattatttg tagctggtgg agttggttct gctccagttt
      841 atccacaagt taaatggttt aaagagcatg gattagatgt agatgtaata attggtgcaa
      901 gaactaaaga attaattata ttagaagatg atatgaaaaa agtagctaaa aatgtatatg
      961 tatcaacaga tgatggtaca tatggattta atggaagagt tacagaccta ttaaaagatt
     1021 tagttgataa tcaaggtaaa aaatatgacc aagcaatagt aattggacca atgataatga
     1081 tgaaatttat gtgccaatta actaaagaac taaatatacc tactatagta agtttaaata
     1141 caataatgat agatggaaca ggtatgtgtg gtggttgtag agttagtgtt ggaaatgaaa
     1201 ctaagtttgc atgtgtagat ggtcctgaat ttgatggtca tttagttgat tttgatcaag
     1261 caatgagaag acagtctatg tacaagactc aagagggaag agctattcta aaacttgaag
     1321 aaggcgatag tcatcatcat agtaattgtg gatgtggagg taacaaataa tggatgctaa
     1381 aaaagtaaaa gtaccagtta gagaacaaga acctgctgtg agagcaacaa attttgatga
     1441 agtatgctta gggtataata aagaagaagc tatggcagaa gctaatagat gtttagcttg
     1501 taaaaaacca aaatgtgtgg gtggatgtcc agtaggaatc gacataccag ggtttataac
     1561 aaaaattaaa gaagatgata tagaaggtgc tgctaaagta atagctaaga gcagttcatt
     1621 accagctgtt tgtggtagag tatgcccaca agaaagtcaa tgtgaaggtg tatgtatact
     1681 tggaataaaa tcagatgctg tatcaatagg taaattagaa agatttgtag cagattggtc
     1741 aaaagaaaat gacataaatt tatctgatac agagcctaag aaaaatcaaa aagtagcagt
     1801 aataggaagt ggtccagcag gtctagcttg tgctggtgat ttagctaaaa aaggctatga
     1861 tgtaacaatc tttgaagcaa tgcatgagcc aggtggagtt ttaacttacg gaatacctga
     1921 gtttagactt ccaaaacaag ctgttgttca acctgaaata gacaatataa gaaaattagg
     1981 tgtaaaaata gaaactaatg taattgttgg taaaacaatt acagtagatg aacttataga
     2041 agatgaagga tttgaagcta tattcatagg ttcaggagct ggtcttccaa tgtttatgaa
     2101 tataccaggg gaaaatgcaa atggagtgtt ttctgcaaat gagtttttaa ctagagtaaa
     2161 cttaatgaag gcttatagag atgactatga tacacctatt agttctggta aaaaagttgc
     2221 tgtagtaggt ggtggaaatg ttgctatgga cgctgctaga actgcactaa gattaggttc
     2281 agaatcatat atagtttata gaagaagtga aaaagagctt ccagcaagag ctgaagaagt
     2341 tcatcatgca aaagaagaag gtattatatt taatacatta acaaatccta aggaaatttt
     2401 agtagatgaa aatggatatg ttaaaggtat ggtttgtata agaatggaat taggagagcc
     2461 agatgattct ggaagaagaa gacctataga aatagaaggt tctgaatttg tacttgatgt
     2521 agacacagtt ataatgtcac ttggaacaag cccaaatcca ctaatatctt ctacaacaaa
     2581 gagtcttaat ataaataaga agagatgctt aataacagat gaaaatggtc agacttctaa
     2641 agagggtgta tttgcaggtg gagatgctgt tactggagca gcaacagtaa tatctgcaat
     2701 gggtgctggt aaaacagcag cagcatcaat agatgaatat ttaaaagcaa aagttaatgc
     2761 ttaatttgta aattaaagag agggtgtctc aaaatgaact ttttagttca tgaggcactt
     2821 tttttgtaca aaatcaaata tgttttaatc atttcaacaa tgaaaatttc attcctgtag
     2881 aaagtctaac ttttaagtct tagtacaatc tctattttga tgtagccact tttttagatg
     2941 gtttaataat ttatcagtta ttattgtaat atttgatact aagtaacata actttgtcta
     3001 actatgataa aatagttata caataaaggt cttgtaagga gtgaataatg tgtggctaat
     3061 aaaatcagat ttgtcaaatc taacattaaa taatagaaaa ataaattgtg taattaatgg
     3121 tattttaata tgaaaaaaag agaaaaagta tttgatgggc tagtttttaa gcatatatta
     3181 atcttattaa tactattagt tttgattgat ttaacaagca ccatcatata tgcaagtaac
     3241 tctatggaaa ttacttctag aaatatgatt gaggcatcaa aaagagaact tgaaaactat
     3301 ttagaagtaa acatatcttt attaaaagct cttagtcaag atgatagatt ttctaatggt
     3361 gaaacatcac taattgaaaa gggaaaatta ttaaggccat atcaaaagga atataatctt
     3421 tttatgattg gtataacaga tacaaaagga aatgcttcaa gtacatatag ggaaaatgtt
     3481 aactcaataa aagataagcc cagttttgag aaagcaatta aaacaaagca agtagtagtt
     3541 tcagatattg aagtcagtaa tgtaacaggt gaaaaagtat ttatcatata tgtaccaatt
     3601 gtaaaaaata atgagatgat tgggaccatt tttgcttctt tttattttca agatgtaaat
     3661 aatttaataa gtagaagcaa ttttgatgat tctattaaat ttctaatgat agataaagat
     3721 tatactatta tttctcatcc aaacaaaaaa tatgtaaatg ataaaagtaa gatgcttgat
     3781 ttagaaggga atattatagg aaccactaaa agtgaaattt taaaaaatat aaataaaaaa
     3841 tgtcaaggta attttttatc ttgggataat tggagattat ataatgtaaa atatacgaac
     3901 ataaagtgga ctaattggac tttagtatca aaatgtaata tatttaagaa ctttaaaaat
     3961 ctaatagtta attttatgat aaagttgtat ttttatatag taatatttat gatattgtgg
     4021 aaattaagta atgctaaatt aatagaacaa cttaaaaaat tggcttatta tgattcttta
     4081 agtggaataa aaaataaaga aaagtttaga aaagattcta tgtatatttt aaagaattat
     4141 tatcaagata atttttactt agtacaattg gatgtcaata aatttaaata tataaatgag
     4201 atgtttggat atgctgaagg gaataagata ttaattcata tatcacaggt tttaaataat
     4261 aatacaaata aatatgaaat ttgtgctagg atggataatg accattttat attgttgatt
     4321 gcttgtaaca ctgaagatga acttttaaat agattatcta aaataaataa agaaatttgt
     4381 aacttaaata ctactaactc atctaagtat aaaattgtta tgtcaagtgg aatatataag
     4441 attactaaaa aggatgatat taaaaagatt gacttgttaa ttgatagagc aaatattgca
     4501 gcaaaaagta aaaaggaaaa gtatgaacat tcatattcat tttttaatga agatacaaga
     4561 aatcgattgt acaaggaaaa acgattggaa gataatatga ataaagcttt agaaaaaggt
     4621 gaatttatag tatattatca acctaagtat agtttagatg atgtaaatga aattgaagga
     4681 gcagaagcct tgataagatg gaatagtcca gaatttgggt ttatttcacc tatagatttt
     4741 gtacctttat ttgaaaagaa tggttttatt gtaaatattg atatgttcgt gtttgaagaa
     4801 gtatgcaaaa cattaaacaa gtggataaat aaagggtata ctcctgtacc aatctctgta
     4861 aatatgtcta gagttcattt atatagggat aattttatag aaaatataac tgatttgata
     4921 agtaaataca atatatctcc tgagtttatt gaacttgaac taacagaaag tgttgtattt
     4981 gataatttaa atatattgat tgatataatg aaaaagatta aagagatagg attccttata
     5041 tcaatggatg attttggttc gggatattca tctttaaatc tgttaaaaga cctttctttt
     5101 gatattttaa aattagatag aggattttta atcgaaacaa cagatacaaa acgtggaaaa
     5161 attattattt ctaagattgt ggaaatggca aaagcgattg atattaaagt aatctgtgag
     5221 ggcgtagaaa cctatgaaca agtagagttc ttgaaagaga taggttgtga taaggttcaa
     5281 ggatacttat ttgctaaacc tatggtatta gatgaatttg aaaagcactt aaactttaaa
     5341 tttgattaat cattaataat tcttaggcta tgagataccc taacaactta cttacaaata
     5401 tgtaagttaa ttgttagggt atttttatgg ttaaagtagt atattcacga tattatggta
     5461 ttgtagtaaa aataaaaaat tatggagaat ataaaatgaa catattgagt attagaaata
     5521 tatcaaaaac atattgtaga aatattccat ttaaagcatt agataaggtt agtctaaata
     5581 tagaaaaggg agaatttgtg tctgttatgg gaccatctgg aagtggtaaa tctactcttt
     5641 taaatataat atctacagtt gatagacaga gtgaaggtga ggttatatta gatggatatg
     5701 atgtaagtaa attagaagga gaaaaacttg ctgaatttag aaggaaacaa cttggttttg
     5761 tatttcagga ttttaattta gttgacactt taactgttgg cgaaaatatt atgttgccac
     5821 ttacactaga tggggcaagt atcaaagata tgaatataca aactaaaagt atatctaaat
     5881 ttttaggaat agataaaatt ttagatagaa aaacctatga aatttcagga gggcaagctc
     5941 aaaggtgtgc tattgctaga gctattataa ataaacctgc catacttctt gcagatgagc
     6001 caactggaaa tcttgattca aaatctactg atgatgtttt gaaattattt actaggataa
     6061 acaaagaaca aaatgtaaca acacttatgg taactcatga agcatatagt gcaagttatt
     6121 cagatagagt aatttttata aaagatggtt gtatatatac agaaataaaa aaatctgaaa
     6181 gcagtaattc tttctattct gatatactag ctgttttgtc tcaaatagga ggtgtaagat
     6241 agtggatttt agaaagtttg cttataataa tatagttaga aatttcaggg catatttagc
     6301 atatttttta agttctgttt tttctataat gatatttttt gtttttgcag tgtctatgtt
     6361 ccatccgatt ataacaaaat ctggaatgca gagtggttct actgcattta tggctcttat
     6421 gacttcagaa ttaataatat taggttttag tctacttttt atattgtact ctttaggaaa
     6481 tttcttaaaa tatagattga aagattttgg agtattgatg ataattggaa tgagcaacaa
     6541 acaactgaaa aaattgatat taattgaaaa tttgataata gggtttttag cagtgatgtt
     6601 aggaatatta cttggtttat caatttcaaa attgttttta ttgtatttaa gcaaactgtt
     6661 ttatatgaat ttaactgaat tttattttcc agtaaaagca atactattga ctattgtatc
     6721 atttatgatt ttgtttttaa taacaggacc aatgagctta aaattattga gtaaaaagag
     6781 tattttagag cttttagtag gtacaaaaaa gcctaaaaaa gagataaaat cttcaaagct
     6841 atttggaata attggtgcag tgtgtcttat attaggatat gctatgataa tatttggcaa
     6901 taagttaaaa ataaatggag gtatgtatac aacagcacta ttaattactt tggggatatt
     6961 tttatttttt tctcaattca ctattttgat attaaagtat ttaaaaaata aagaaaaatt
     7021 ttataagaac aaagtaaata tgttacttat aagtaatttg atatataaat taaaggataa
     7081 tacacgattg ttatttttaa taacaatact tttatcggct actttagtag catttacaac
     7141 aacttcaaca cttgtaagct ctcaaggaga atcttctaaa aataatttcc caatggttta
     7201 ctcatatttt tcagagcata ataatgaaaa agaatatgaa gaactacaac aaattagaga
     7261 agcaatcaaa ggatatgatt ataaggagtt aagttttcct gtacttaaat ataataggga
     7321 agtcttacta agtgtaaaga gttataacaa attatcaaag gaattggggt tagataaaat
     7381 tagttcaaag ttagaaaggt atgaaggaat tataattccc agtagcattt cacaagaaca
     7441 tataaattct ttaaaacaat taaaaaattt aaatataaaa aatttaaata tagaagtaaa
     7501 aaaatcaaaa aataaaataa tttttcctac aggactgttt agtaaaattg tagttataag
     7561 tgatgactta tacgatgaag taaaaggtga attttcaaaa attaattttc atggatttga
     7621 ttataaaaac tggcaaagca gtgcaaagat aactgaaaat ttaaaagaaa aacattttaa
     7681 tttggataga gaatataaca ggtcatattt tttaacatta ccagatatgt atttagtaga
     7741 gttacaacaa agtaaaattc ttcaatttat gggtgttttt ataggagtga tattatttat
     7801 agcagttttt agttttttat actttagatt atatacagac gagatagaag ataatgtaaa
     7861 gtacaaaaaa ctatcaaaaa taggtctatc ttttaaaaat atgaataaga ttgttagtat
     7921 agagataggt acattgtttt ttataccgta ttttatagca attataaata gcataatttc
     7981 tttactgttt ttaaatcaag tattaaataa tagttttaag ttagaaaatt tgggtatatt
     8041 actactgata tcatctatat attcacttta tttttactta ttaaaaaaaa tttatactag
     8101 aaaagtttgg ttttttgatt aaagtggtat ataatagata tataaattaa tatttaaaaa
     8161 gtagttaata ttaggggagg gcatttgcac ctcccttgta atatgtggaa aattgaatat
     8221 tagaagaagg aggagacttg atggaaaatc aacaattatt aggaacagaa cgaattagta
     8281 aattactact aaaatattct ataccagcta taataggtat gttggtaaat agtttatata
     8341 atgtagtaga tagaattttt attggaaata taccaggggt tggaccactt gcaataacag
     8401 gtcttggtgt aacaatgcca ataatgacaa taatacttgc atttgggatg ttgataggta
     8461 taggaactac tactaccata tcaataaaac ttgggcaagg taaagtagaa gaggcaagaa
     8521 aacttatagg aaatgcaatg acgttatctg taataacagg aattatcata atgatacttg
     8581 gaatattatt tgcaaataaa atacttacat tgtttggagc aagtgaaaat actttaatat
     8641 atgcaaaatc atatataaat attatattat taggtacagt agtaaatctt ctttcctttt
     8701 ctttaaacca ctcaataaga gctgatggta gtcctaaaat ttcagcagga ataatgatag
     8761 taggatgttt aactaatata gttttagact ggatattaat atttggattc aatttgggaa
     8821 tacaaggagc tgcaattgct acagtaactt ctcaggctct tacagctatt ttaactatag
     8881 ggtattatat aagtggaaaa tcaaacttac gattcagtaa atctaatcta aaattagata
     8941 aaaagctaat aaaagcagtg tttgcaatag gtatgtcgcc atttgcgatg caacttgcag
     9001 caagtttagt tcaagtaata tcaaatattg cacttaaaac tcatggtgga gatttagcta
     9061 taggggctat ggctactatt tcttccattg caatggtatt tttgatgcct atctttggaa
     9121 taaatcaagg agcgcaacct attataggtt tcaattatgg agctgaaaaa tatgataggg
     9181 ttaaaaaagc atatttaggt tcattagtag tagctactat aattttatgt atgggtatgg
     9241 tagtagttat gcttttccca gaagctatta taggtatatt taataaagac cctgaactta
     9301 tgaatatatc tgttaatgga ttaagaatat acttacttat gttgccaatt gtaggcttat
     9361 cagttacagg aacaaacttt atacaatcta taggaaaagc aaaaatggct atgttattga
     9421 gccttttaag acaagtaatt ttattgatac cagcagtatt aattcttcct acattcttag
     9481 gtttacaggg tgtatggaca gctcaaccag tgtctgattt tatagctaca gtaattacag
     9541 gtatagttgt atttagagaa ttaaaaagat atactcctaa aactgaaaaa ttaaatgaaa
     9601 atgaaagact aaatgagata actactgagt aaaaatataa attcagataa ttgagcaaga
     9661 aattgcaaaa aatacgatta tatgataaaa taaaaccgct gtcaaggata agagaaattc
     9721 taattatgga gtgattttat ggaatttaca aagaaaagca aattaaaaaa tatgtatgta
     9781 aacatgaatg tagctagaat gttgtctaag ataaatgagt ataagggtag gcaactgctt
     9841 tacaaaaaac aaccaaaaga aattttagaa aacctagaaa aaaaatcttt agtagattgt
     9901 tctgaatcta catacattgg aaatcaaaga gatagtagta attttaatct agaaaagttg
     9961 ataagtaatg aagttacacc tagaagtaga gaggaattga gtattgttga atacagagat
    10021 gtggtaaaaa ctattaacag tgcttatgag agtattccca tcagttcaca aacgattctt
    10081 gagcttcatg ggtacttata taaattttca tctactagag gaggaagtta taagtcagat
    10141 aatgatttta ttgaacacaa tttaaaacct agcgaattta taagtattga ttcaagtgtc
    10201 aataaagttg aaaaagctgt agaagaaata tgtgaagctt ataatacatt gatagaggaa
    10261 gatgaaattg atatattaat attaatttct gcatttgtgt tagatttcat attgatacat
    10321 ccattcaaag aaggtaatat aaaaatggcg agagtactta tcctattgtt actaaataaa
    10381 aatgggtatg aagttggaag atatataagt ttaggaaaga tatttgatga tagttcatat
    10441 gaatattata gtaatttaaa ttatttgaaa gcctcaatag gtagtgaaaa agcagatatg
    10501 aatgcatgga ttgagtattt tttagagacg atattaactg catatgagaa gctggatgat
    10561 agtttaaata tatctgataa gaaaagacaa acaaaaacta gtagaataga aaaaataata
    10621 aattctaccc ttggatattt tacaaaagaa gatataagag atttatgtcc tgacattcca
    10681 gaacctacta taaatagagt ttttaataat ctaagaaaac aagataagat agaagttgtt
    10741 gcaagaggaa gaagtgcaaa atggaagaaa aaatattaaa aaatgtttaa ataactaaaa
    10801 tggtatagtg ttttacacta taccattttt aatgtcatta gcatgagcaa taatttaaca
    10861 acttaagcaa tatcaatttt atttattgat tatttttgaa ctgaaaaatg gagttatatg
    10921 gtatactaca ataataatta attttggatg agaatatata acgttacaga atatcttagg
    10981 agtatatgta taaaaaatat aataaaagtg tgaggtttag taattaacaa attatgtgga
    11041 ttcacacttt tttataaaat aaagatactt agcagaagaa tattttagtt gatatgttta
    11101 taagatagta cttgtttggg taaaagtata aatagtaaaa aagtagaagt aatgtgtata
    11161 aaaacataag ttacattctg taataatagt tattttataa ttcaacaaaa gaatagaatg
    11221 ggtatatttg tgaaataata atataaaata atcttaggag tgatcttatg aagaaaaaat
    11281 tattatatat aaatgtaaat tcaaaacctg aagacttatc ttcaagtaaa actgtagcaa
    11341 gaaaatttat aaataaattt atggaaaaaa acaaagattt tgaggttgaa gagatagacc
    11401 tttataaaga acatataccg agacttgagt atcagtactt tgaaaagaga aatagcatag
    11461 ttagtgaaga aaatgctaaa aatttagatg ataaggatag aaaagagctt acaaagatta
    11521 gaaatctttg tgaccaattt gtgagtgcaa gtgtttatgt aatagcagca cctatgtgga
    11581 gtttatcttt tccagcacca cttaaagagt atatagattg tataattcaa gatggaaaaa
    11641 ctatatcttt tgaaggcaat gataaaccac aaggaatttt aaatgatatt gatagaagta
    11701 tggtatatat acaatcttct ggtggacaca taccatgggt cttgaagcca gttatgaata
    11761 aagggttaaa ttatgtggaa agtattatga aatttatagg aattaaaaaa tttgatgaat
    11821 tgttagtaga tggaactgga actagtgaag aagaaagaca agctgcaata gaaaaagcat
    11881 ctgaaaaaat agatggtata atagatggta tgaaatttta attataatat tttattaaaa
    11941 atataaagga aaaacctctt ttaatgtaga aacttatatt gaaggaggcg agaatcatgc
    12001 gagaagaaaa aagtaatgaa aagtatgatt gttattggtg taatcaagaa aataatttct
    12061 gtgtagaaat aaaagataat atagtaatga tagatgatgg cactggtacg ttaaaacaag
    12121 ccgttttcat agggtataaa caaatccaaa ttaatttaaa ttgttcacat tgtcaaaact
    12181 taaatagaat aaaattaaat ttgtagaatt ttaaaatgga aattattgaa ggaattaaaa
    12241 atagaaagtg ttaatattta gactgaaaat tatattttat acaataaaag tttatttaaa
    12301 taacattgta ttttaatatt tattttcagt cttactttat taaaattatt ttttggttat
    12361 gtctggaaaa tatctgtcta ctaatttttc tgaaatattt tttaattggt cagccattga
    12421 agtcagactt aataaggcta tcaataaatc atctttattt tctggattta tactaatatt
    12481 ttcaaaatta gactctataa agtccggtat attctttctt tgattttctt ttattaacat
    12541 gaatttttcg taacatgaaa ctaaatcttt ttcactgaaa ttatcctttt catacacacc
    12601 atgtaagatt cttttaattt cttgtattgt aagtgtattt ttcatagaat aaataattat
    12661 catctgtaaa atttgttctt tagtatactt ttttccctta actggtttga ttaatccctc
    12721 tttgctgtaa ttatttatca tggttttagt aagaatttta tcactttcaa atcttttatt
    12781 aggagaaagt ttattgtcaa ttagagaaat aatttgatcc atatataagt caatagaggg
    12841 aatatcgttt gaagttatat ctgcattatt tagtgtttct agtattatag tattaagttc
    12901 attattcatc atatgttacc tccataatat atataataca ctaaattaga aagtaaaaca
    12961 atattaagac ttgtaaaaaa aacataaagt ggtataatta aatatataat atagtaatga
    13021 aaactatatt tatgaatctg atttttaaaa tacataattg taggaggacg aaatgtatca
    13081 atttttttta aagggtagag acccaataag cagtttaact cattttatag gtgcttgttt
    13141 atctctttta gcaactataa ttttagtttt tcaatctgtt acattacagg aaacttctct
    13201 cttgatgata gtatctgtat cggtatttgg actttcacta attgctttat atagtgcaag
    13261 ttcgtattat cattttttaa aggggacacc agaacaagaa ttgtttttta gaaaagtaga
    13321 ccatgcaatg atttatgtat tgattgctgg ctcttataca ccaatatgtc tgaattttat
    13381 ggaaaaaaaa gaaggcataa tatttgttac agcaatatgg atagttgcat ttattggcat
    13441 aataataaaa atattttgga tggatgcacc tagatggtta tctaccagta tatatttact
    13501 tatggggtgg gcaattgttt ttgatataaa tgcattcaat tcaattccta aggattgcct
    13561 tagactatta attatggaag gtgtatctta ctctataggt gcaattattt atataattaa
    13621 aaagcctaat ataagtcctg aatttggatt tcatgaaata tttcatattt ttattatgat
    13681 aggttcttta tttcactttt tagcagtttt attgtatgtt ttatagtttt aaaagatttg
    13741 attaattgat actaaaattc tacaatgaat aaaatggaac tgccttatat agattatatc
    13801 ttcgacaata agacagttcc ttattataaa tattaaattc tacttataat aaaattttga
    13861 taaaaatagt ccattcaaaa tgcctattcc ataattcctt taatgtactt ttcatttacg
    13921 acatatagtt tgaatttatg tactataatt atatcctcta aattctctga aacactaaca
    13981 attctgacac atttgtttct aatttctaca ggtaaatcta aatcatttgt taaattcaca
    14041 tagtcatcat atttatacat aaaatcatcc ctttacatta agatatactt attatactat
    14101 attttaataa gtttttttaa attattacaa tttttcccga aatttcattt tttatacata
    14161 aaatttccaa attaggtaaa gattaaattt tttattgtat aaacaaaatt tacatataaa
    14221 atattttatt caaattttta aataactatt gccaattttt gaaaaatata ttattattaa
    14281 tagtaacaaa aaactgtaaa tttagaatat taataaaaat tatttgggag gaaattatca
    14341 tggtgagatt aaatatagta aaattaaata caaaattaaa tcatcaccat catcatagat
    14401 taaagggatt gtaatatgaa attaattcat agacacaagc cctgttttta gtgtaattgg
    14461 tcttgtatct atgatgggaa gtaattttag gagaaaatta tagccatata ggtataaagc
    14521 ctatatggct tttttattgt tttaaatttg caaatataag agtaaattta atgaagaggg
    14581 tgagaatgtg aaatttttga ggattgaaga tgaagttatt tattctaaaa aaagatataa
    14641 attaaaaagg gaaatagata aacttttttt ggatgaagaa tattttcaaa tagaaccaca
    14701 attatttgaa gaatatgatg aatttacaac tataaataat aaaattccag aagaatctat
    14761 ggtaaaggtt gtaaatggaa aagtaatggt acttagagct gatataacta caagtataat
    14821 aaaaagcctt gtaccaagat gggaagatgg tttaaaactt aagctttttt ataattcatc
    14881 aatatataaa aataaaaata cagttggaat aaaagagata agacaaatag gttgcgagta
    14941 tctaggagaa gcctctgtag aagcagatag agaagtagtg aaattagctc ttaagatact
    15001 tgaaaaatac aataataatt ttattttaga ggttgggagt agcaagtata ttcatggttt
    15061 gttagaagaa ttaaatttaa ataagaattg tgaaaatcaa attaaaaatt tactatatac
    15121 gaagaacact catgaattaa aagtatatat tgaagaactg aaaattaagc gtgaagtaaa
    15181 agagctatta tcaaatattt taagcttgca agggaattta tacaacgtta ttgaaaaatc
    15241 aaacaagttc tattgtaata ataagatgaa gcaagctctt gaagaattaa agcaagtaaa
    15301 taatttaatt gaggaatgta attttttaga taaggctaga tttgatttat caatgattac
    15361 tatgcttgac tattatgaag gaattatgtt tagaggatac tacccaaact catataaaga
    15421 aattcttagt ggcggaagat atgattcttt aactaaagag tatggaaaag aaattccagc
    15481 cattggattt acactaagtg ttgatgagtt aatgaagtat gtatataagt aaagtttaga
    15541 aggagggatt gttttggatt atttgactat agcactagca aaaggacgaa ttgaagggga
    15601 atcatttaaa aaatttaaaa aaatgggtct aggagatagt atagacacag atacgagaaa
    15661 actaattttt aaagatgaag aaaataaaat tatatatata catgtaaagc catcagatgt
    15721 agttacatat gttgaaaaag gagtcgctga cctcggtata gcaggtaaag atactatttt
    15781 agaaaatgag acagatgtat atgaaatata tgatttaggt tttggaaaat gtaaatttgc
    15841 tgtagcagga ttaaagggag atagcatata tagagaagat gaatatttaa aagtggcaac
    15901 aaagtatccc aatatagcaa aaaagtattt taaagagaaa ggtcaaaaaa ttgaaataat
    15961 aaaattaaat ggttctgtag aactagctcc aatagtaggg ttgtcagatg taattgtaga
    16021 tatagttgag actggcaata cacttaaagc aaatggtctt gaaatattag aagacatatg
    16081 taatataagt gctagaatta tatcaaatag agctagctat agatttaaat atgaacaaat
    16141 tcagaatata attcgtttat ttgaagaact tgataattaa aatataattg agctttataa
    16201 ggagggattt aagttgagag aaaaagaaag cataagagag ttaaggggat atgaaccaaa
    16261 tcacgtaaac tgtaaagtaa aacttgatgc aaatgaagga agtaagaggt tgtttaaata
    16321 ccttattaaa gaaatttcag atagtgatat agatttaaat ttatatcctg aagattctta
    16381 tagtgatttg aaagaatcta taatagatta cataaatatt tctggagtaa ataagaaaaa
    16441 tcttctagta ggaaacggtt caagtgaaat aattgattta ataatacata cttttgtaga
    16501 taaagatgaa gtaatattga gtttctctcc aagttttagt atgtattcta tatatagtca
    16561 gataaatggg tctaaattta taggtgttga aagtgatgaa aatttagtta taaatataga
    16621 taatgtgatt gaaaaagtaa aggagaataa tcctaaaata gtaattgtat gtaatcctaa
    16681 taatccaact ggaacaatat taaagaggga agagataata aagcttttag attcaactaa
    16741 tagtctagtg gttttagatg aagcatatat ggattttgga gaagaaagca tgttaagtga
    16801 tgtttttaag tatgataatc taatagttct tagaacttta tcaaaggcat ttggattggc
    16861 tggaataaga acaggatata tgttatctaa tagtagttta ataaattctg ttgagaaagt
    16921 aagacctcca tataatttaa attcattatc agactttatt gctacaagag cacttagaaa
    16981 taaagatgtg gtaaaggctt atataaagga agtaaaagag gaaagagaag ttttatatga
    17041 agaaatgatt ggtatgggaa ttaaagcata caaatcacaa gcaaatttta tattatttta
    17101 ttctgaaatc gaaaatttat cacaaaaact tattgataga ggtgttttaa taagaaaatt
    17161 tggtggaaag ttagaaaatt attacagagt tacaattggt gataaagaag aaaattctat
    17221 gtttgttgga gctataagag atattttgaa aaaggagaaa taggtatgag aatttggaag
    17281 gtagaaagaa atactcttga aacacagatt ttagtagaat taaatattga tggttctggt
    17341 aaagctgaaa tagatactgg aataggattt ttagaccata tgcttacctt aatgtcattt
    17401 catggcaagt tcgatttaaa agtgatttgt aagggtgata catatgtaga tgaccaccat
    17461 agtgtagaag atataggtat agctataggt gaagcattta aaaatgctct aggtgacaaa
    17521 aaaggaatac gaagatattc taatatctat atacctatgg atgaatctct atcaatggta
    17581 gcaatagata taagcaatag accttatctt gtatttaatg ctaaatttga tacccaaatg
    17641 attggtagta tgagtactca atgctttaaa gaatttttta gagcttttgt aaatgaatcg
    17701 agagtaacat tacatatcaa tctcttatat ggggaaaatg accatcataa gatagaaagt
    17761 atttttaaag catttgcaag agctttaaaa gagggcagtg aaatagtttc taatgagata
    17821 gcatcttcaa agggggtttt gtagaatgaa tataatagta gactatggtc ttggaaatat
    17881 agattctgtg tctaggggtt ttagaaaagc tggaatagaa actaaaattt ctagtgatat
    17941 agatgaaata aaacaggcag attcacttat acttccaggt gttggagctt ttagagattc
    18001 tataagtgcc ttagataaac taggattgat accaataata aaggagcatg tttctaaggg
    18061 taaatttatg ataggtatat gtctaggaat gcaattactt tatgaaaaaa gttatgagta
    18121 tggagaatat gaaggattag gacttataaa aggaagtatt gataaactgg atataagttt
    18181 aaaagtgcca catatgggat ggaataatct aaaatttaat aaggcaaatg atgatatact
    18241 taaatatata aatgaagatg attatgtata cttcgttcac tcatattatg caaattcatc
    18301 aaatgaagaa ctaattgcat tttcagaata tgaaaagaaa atacctgcta ttgttagaaa
    18361 aggcaatgta tatggtatac aatttcatcc tgaaaaaagt ggagaagtag ggttaaatat
    18421 attaagagca tatggggaga tgataaaatg ataatatttc cagcaataga tataaaagat
    18481 aataagtgtg taagactcac acaaggagaa tttgacaaag taaatgtata ttatgataat
    18541 ccattagaag tagcatataa atggaaaaat gaaggagcag aatatataca tatagtagat
    18601 ttaaatggtg ctagaagtga atttggtata aatacaaaaa taattgagga tatagcaaac
    18661 aatatagata tacctattca agttggtggt ggagttagag ataagggaaa agtcaaaagt
    18721 ttaataaatg ctggtgttac tagagtaata ttaggtagta tagcgattga aaatttgaat
    18781 ttggttgaag aattggtcaa tgaatataaa gagaaaattg tagtttctat agacgctaaa
    18841 gatggaaaag tagcagttag gggatgggaa gttgtaagcg atgtagactc attaacatta
    18901 tgtaaacaac ttgaaaagat aggtgtacaa actattgttt atacagatat atcaaaagat
    18961 gggatgttgc aagggccaaa ttttgacata tatgaaagaa tagcaaagga aacgtcatta
    19021 aatgttattg cttctggagg cgtaacttct atagaagacg taaaaagact aaaagctatg
    19081 aacttatatg gtgcaataat aggtaaagcg ctttatgata aaaagataga ctttaaggag
    19141 gcacaacaat tatgcttact aggagaataa taccttgtct agatgtgaga aatggaagag
    19201 ttgtaaaggg aaaaaaattt aaagatatag tagatgttga tagtccagaa gtacttggaa
    19261 aattttatag tgattgtggt gcagatgaac ttgtattcta tgatataact gcatcaaatg
    19321 aagagagaaa gacatcttta gaatttgtga caaaagttgc agaaaatata aatataccat
    19381 tttgtgttgg tggaggagta aataaattag aagatttcac tgatatttta agaaaaggtg
    19441 ctgataaggt ttctataaat tcatcagcag tcaaaaatcc tgaattaata agggaagctt
    19501 cattaaaatt tggagcacaa tgtgttgttt tatcgataga tgcaaagaaa aatgaagagg
    19561 gttcatggag cgtatacgta aaaggtggaa gagaaaaaac taatctggat gcaattgaat
    19621 gggctgttaa aggtgtagaa cttggagcag gagaaattgt tgtaaatagt atggacgaag
    19681 atggaatgaa aaatggatat gatatagaat tattatcaaa gataacttct ttagtaaatg
    19741 tacctgtcat agcatctgga ggcgctggaa aaaaggaaga tttttatgag gcggttaata
    19801 aatccaatgt agatggaatt ttagcagcat ctgtttttca ttttggcgag ataaaaataa
    19861 acgatttaaa gaaatattta aaagacatgg gtgtagaagt aagattataa gttaaatact
    19921 aaaaggagat tagaaatatg gataataagt gtaacaatgt atacagtgat gaagtagaga
    19981 aatttataag aagtataaag tttgatgata aagggttagt ccctgttgtt gttcaagagg
    20041 tagttagcaa agatgtactg atgttagcat atatgaataa agatgctata aagaaaacct
    20101 taaaagataa agtagcttgc tattttagta gaagtagaca agaactttgg gttaaaggtg
    20161 agacatctgg taatactcaa aaagtagtta agatgtctta tgattgtgat gtagatacta
    20221 tactactttt tgttgaacaa actggtgtag cttgtcatac aggcaattat tcttgttttt
    20281 acagagactt gtttgatgat agttcaaaaa tggagcttga agtacaaaca aatatattga
    20341 aagaattata tgatttaatc aatgaaagaa aaaataatcc agttgaaggt tcttatacta
    20401 attatctttt tgaaaaagga atagataaga ttcttaaaaa agtaggtgaa gagagtagtg
    20461 aggtaattat agcatcaaaa aataccgata aaagtgaact tatttacgaa attagcgatt
    20521 tagtgtatca tacattggtt ttaatgatag aaaaaggtgt tgaaattgat gaaataaaaa
    20581 aagaattact taaaagaaga aaatagaata ggatagatta atggtaataa gaaaatatac
    20641 cgcttttaat aaaaagtggt atatttttta ttttatattt tcgatttata gaataatatt
    20701 taaattactt gataaaatta actatatata taatttattg ataaaataat tgtagtacat
    20761 tatttatttt agaaaaaaga taattatcta attatattta aggataataa tatgaaaata
    20821 atttttatat taaaaaatat gaatgaaaat agtgggtttt ataaaaaaca tatttagatt
    20881 ttaacatcta aaaggaattt tcaaacctaa tatttcattt ttaaataaaa aaataaaata
    20941 ttagttttga tttatggttt aaattgggtt ataataaatt gtcaaattat ttattaatat
    21001 aaaatagact ataaaacaag caaaaatcat actattatat aaaagacctt aaagatagaa
    21061 aattacagaa agaagccaaa atgtttttga aaaaaatgaa attttattgc aaaaaaatca
    21121 aaatcaattt aacttaatag ttataatcta tttttagtgt tacaaatata caatgtatat
    21181 tatacaatat aaaaaatacg tttatttata aatattatta tatttggatt tttggttttt
    21241 ataatttttt tatatttaaa cataactaaa agtaaaagat tacgaaagct aagtagagtt
    21301 tattttattt taataaataa aaaagctatt tttctatata ttggcataat atatgcttat
    21361 ttaactatga aattaaatag gattaatgag gaggaaaaga atgggaagta atgaactgaa
    21421 aaagactctt ggcgtatcag cagcattatc aactgttgtt ggttctgtta taggagcggg
    21481 cgtatttttt aaaccacaag cagtctatac attaactgga ggagctccag gtcttggtat
    21541 attggcatgg ttaatagctg gaatcataac tataacagct ggtcttacag ctgcagaagt
    21601 atcagttgcg ataccaaaaa ctggtggaat gatggtatat ataaaagaaa tttatggaga
    21661 caaattaggt tttttaactg gatggatgca aattgtatta ttttatccag ggatgatggc
    21721 agcattaggt gttatatttg gagaacaagc atcagcacta attggtagcc catcactttt
    21781 acttccaata gcaattggaa ttatagtaat agttgcaggg cttaatatgt taggttcaaa
    21841 aactggagga gtcatacaaa ctgtctctac aatttgtaag ttaataccac ttattttaat
    21901 aatggttgtt ggatttatta aaggtggtgg aaataatcca atacttacac ctatggttgg
    21961 tgagggatta agtctgggta gtgtactagg tcaagtttta attgctatat tatttgcttt
    22021 tgatggatgg atgaatgttg gtaccttagc tggagaaatg aagaatcctg gaaaagacct
    22081 tccaaaagct ataataggtg gattatcagt tgttatggct gtttacttta taataaattt
    22141 agcatatctt tgggtattac cagctaatga attatcaaat tatgcttctc ctgcatcagc
    22201 agttgctgaa gttatatttg gttcaatggg tggaaaaata atatctgtag gtatattaat
    22261 ttcagtgttt ggagcattaa atggattttt actaactggt tcaagggtgg catatacttt
    22321 agctacagat aagactttac caaagtatgg tatattttct aaattaaatt ctgctcaagt
    22381 tccagcaaat gcaatagcat tagtatctgt tattgcatct atatatgctt tgtcaggtca
    22441 atttaattta ttaactgact tagctgtatt tgctacttgg atattctatg tattaacttt
    22501 tataggggtt atgaaactta gaaagactca tccaaatata ccaagagagt ataaagttcc
    22561 attatatcct attgttccta taatagctat agcaagtggt atatttgttg tagttaatca
    22621 attgtgtttt gcaggtatga aaactactat gatatctata ggaggtcttg taataacagc
    22681 tataggctta ccagtgtatg cttatatgac tagaggaata aaaagataaa ccaagtagtt
    22741 tacaaatgct ttataattaa aataaaagag actgtctcaa aatagagata agtctctttt
    22801 ttattgttaa aagggtaaag agatgtttta ttttataaaa aaagagtgtt ctatgaacta
    22861 aaaagtttat tttaaggtat tcactttatt tttagttttt gaattataaa attaaacatc
    22921 taaaaaatta tttgctttaa aatactttat tttaaagtgt ttttttatca aactaagtga
    22981 tatctatata acaaatatta tacataggtt ttatgaaaat taaatctttc tgttatatat
    23041 aatagaatat tgtattatat agaaaatatt acctgattaa tatcgtgatt tataaataag
    23101 attagaaaat tttatttgat aacaaaaatt agacaatatg aatatataat gtatgtatta
    23161 aaaatgtggc aaatagttgt tttggtattt attatttgtt taatatttct aatttataaa
    23221 aaaaaaatta taaattttaa aaattataaa tgacatttta actagaatta attgtaaaaa
    23281 acactatata atactcaatt ttcaacattc tatacaatta tacagaaatt atacagcata
    23341 ataatcaccg aaataacaaa ttttaaaaat taagcaaaac tttttgtcga agttcaacgt
    23401 ctatatatat gtagtgtaaa tttttgggat aaaatactac aaaaatataa atgtaaaaat
    23461 atagtaatat tggaggtcga acgatgagaa ataaaaagaa aaaaataaat agaaagaagt
    23521 tgtatttgct tttaagtgct attgtagtgt gtctggcttt tatagtagtt ggtgttcgcg
    23581 tcagctcttt aaatatgaag gaaaatgaaa ttagtagaaa tgcaaaactg tcaagttcta
    23641 ctattacaga tatagtatct aatacatcaa tagaagttag taaagggcca agtaaaagtt
    23701 ctggaaaaat agcatacata actatagatg atggcccatc taaatttact gacgagatga
    23761 taaaaacttt aaataaatac aatgttaaag caactttttt tatgatagat gggaatatga
    23821 aggaatatcc acagcaagtt aaaaatataa ttaaaaatgg gaacacagcg ggttttcata
    23881 gtgtatcaca tgatattcac aagctttatg ttactagtac atcagcaaaa gaggaatttg
    23941 atacaaatga tcaaactttt tataagataa ctggtaaaca ttcaaaagta ataagaatac
    24001 cttatggaag caaaccatat acaccacaag cctcttatca ggctttagtt gatgctggat
    24061 ataaaatttg ggactgggac ttagatacag aagactggag atctaattct tctcaaattg
    24121 tacaaaatgt aaaaaatcat attaagaata gaaaaggtga agataaagac caacttgtag
    24181 ttttaatgca tgagaaaaaa cagagtgcag aagctttaga ttcagtttta aaattattat
    24241 cagatgaagg ttatgaattt gcgccagtag atcaaaacca aataccaaaa aattattggt
    24301 tacgtaattt agagtagtta aaatataaga atattgattg atatttttag aaattgagaa
    24361 taaaaatgag tgaggtgtag gtatattgaa taaaaaactt tatataggaa tggtcggaat
    24421 attgtctttg atgatggttg gttgtaataa aagtttagca aaagtaaatg atgtggaaat
    24481 cacaaaagaa cagtacaaaa aaacaaaagc agttttatct gctactaata attatataaa
    24541 tgggcagtct ttagatgaat tagaaaaaac tttggataaa aaaggtagaa ataaattaga
    24601 aaatgttata atatcgttta tggtggataa tgaactttta tatcaagagg ctaaggataa
    24661 aggactaact ccaagtaaaa gtgaagtaga ctcaaaatat caagaactag aagataagat
    24721 gaatttgaat acaagctata aggaaaaaat ggacaaagca ggtgttgata aagaatattt
    24781 aaaacaagaa atatctagag atttagcaat agataaaaat aaaaaggcct ttgaagatag
    24841 aataaacata agtgataatg atatggaagc ctactataca agtcataaaa aagattttaa
    24901 tgtagaagaa gtaagtgctt ctcagatact tatatcgact ttagataaaa ataaaaaaga
    24961 agtaagcaaa gataaaaaag aagctttgaa gaagaaggca gataatatat tgactaaaat
    25021 caaaaatgga gaaagttttg aaagtttagc taaaaaatat tcggatgata aagcaactgg
    25081 aaaaaatgga ggacagctag gatattttac aaaggatgat aaaaatgctg agtttacaaa
    25141 ggaagtgttc aaattaaaga aaaatgaagt ttcaaatgtg tttgaaacta gttatggata
    25201 tcatatagtc aaagttactg ataaaagaga aagacaaaaa agttttaatg agtgtcagag
    25261 tttaataaga gaatctattt taaatgaaaa gtatattgag catataaaaa aactgaatga
    25321 agatgctaaa atagacagat agaatttcta acagctcaat cctagcctgt aatcggaggg
    25381 agattttaca ggaatgttta agagtttaaa gagaacgaaa gttgagaaat acattatcga
    25441 taataaagac tctttttata gaatagcata tagttatacg aagaatgaag aagatgcctt
    25501 agatgtggtt caagaagcca tgtataaggc actatactca gtggaaaata ttaaagaagt
    25561 aaattatata aagacatggt tttataaaat tttagttaga acgagtatag attttattag
    25621 aaaaaaccgt aaatataata atatgacaga tattgacctt atagatgaga ctggagagta
    25681 tgataaatat actgatttgg atttaagaag agctttggaa gaattaccta ttgaatacaa
    25741 atctattata atattaagat tttttgaaga tttaaagatt gaagaagtag caataatatt
    25801 ggatgaaaat gtgaatactg ttaaaactag gttatatact gctttaaaaa aactaaaatt
    25861 aaaaattgaa gagtagggat aaaaagaatg acaagcaaag aaaggttaaa taagttaaaa
    25921 gatgagtatc ataaaattcc aatacccaag aaattagata ctataataaa tcatgaaaaa
    25981 atagaaaaca tatatcgaga gaaaaataaa aaagtaaata gattaagatt taaagttgca
    26041 atagcctttg catgtatatt tacagtatta gtaaatataa gtcctgtatt tgcagacaat
    26101 ttttctaaga tacctgtaat tggagcaata gtagaagtaa taactataaa aaattatagt
    26161 ttaaaaagtg aaaattatga agctgagatt gatattccta aaatacgagg tttaaaagat
    26221 aaaaacttag aacaaagatt aaacagtagt tttatggaag atggaaaaag gctttatcat
    26281 caattccaag agagaatgga gaagatacaa tcatcaaaga ataaaggata taaatcttta
    26341 agtttgagtt atagtgtaaa aaataattct aaaaaatttc tatcaataga gatgacaaaa
    26401 aatgagatag aggcttcatc atatgtgagt aaggtacatt atactattga taaaaaaaga
    26461 caaatagttt taactttgcc aatgcttttt aaagatgata agtatataaa agttataagt
    26521 gataatataa aagaacaaat gagagaacaa atgaaaaagg atagtacaaa atcctatttt
    26581 atagatcaaa aaaaagactt gcctgttgaa gattttaaaa caattaataa gtatcaggat
    26641 ttttatttta ataaaaatga agaccttgta atttgttttg atgaatatga agtagcacct
    26701 ggttatatgg gtgcagttga atttgtaata ccatataaag taataaaaga tttgtaaatt
    26761 gaatagtagt ttatatataa atattttaag gaggacaata tgactacata taaaaaactt
    26821 aaaaaatcta tatttaaaat tgctatattt tcaatatgct tattagtttc attagtagat
    26881 acaaacccta tatttgcagg tagttccttt aatgaaactt caaatagtga tacgataaag
    26941 gtgttaaatg ctaagagtat caactttaaa caagacaatt atgaagtgaa tgtgagtatt
    27001 cctaaaataa aaggtttaaa agataaaact ttagagaata aattaaacaa tgagcttttg
    27061 caagatggga aaaaaattta cagtgaattt caaaataaaa tgaaaaagga aaataataag
    27121 ggtcatagat acctaaatgt aatccataat gtcaaaaata attctaagga ctttttatca
    27181 atagaaatga caaaagaaga gatagaagct tcctcatcta taactaagaa gcattacact
    27241 gttgataaaa atagaggaat actattaaat ttaccaatat tttttaaaga tagtagatat
    27301 attaaagcta taagtgataa tataaaagag tagatgagaa atcaaattaa gaaagatgat
    27361 acaaaatctt attttataga ccaagataaa gactccccag tgaaagattt tgaatctata
    27421 aataagtatc aagattttta ttttaataaa aatggaaatc ttgtgattag ttttgatgaa
    27481 tatgaagtag cacctggtta tatgggagca gtagaatttg tgataccaaa tagagtaata
    27541 aaaagactaa gatagatata tagaagattt ttagatagac tggtaaggag aattatatga
    27601 atatatatga acaagcaata agattaatag aaaataatga ggatttcgca tttgctacaa
    27661 taacgtctca ttcaggttca acaccacgtg aaactggagc aatgatgatt gtgaaaaatg
    27721 attctactat atttggctca gtaggaggag gtagtgtaga agcagaatgt ataaaacatg
    27781 caattaatgt tataaaaaat agagaatcaa tgttgtataa atttactcta aacaaatctg
    27841 atgtggcaaa actaggaatg atatgtggag gtactggaga aatacaaata gattttatag
    27901 atagtaaatt aaaaagtaat atagaaaaat tcaataagag actaaaggaa aatacaagta
    27961 aagcatatat atttggtgca ggtcatattt caagagatgt tgctgtgata ctatctcttt
    28021 tagaatttag aacagtagta atagatgata gagaagaatt tgctaattat gaaaggttcc
    28081 cagaatcaga agtagtagtt ttagattctt ttgaaaatat accagatttt ccaactgacg
    28141 aaaatagcta tataattatt ttaacaagag gtcatctata tgattcaagt gctttagaat
    28201 gggctcttaa aagagaaact ggttatatag gtatgattgg aagtagaaca aaaattggat
    28261 tgacgtacga aaaactcatg aaaaaaggtt ttaagaagga agaattatca aaagtacatg
    28321 caccaatagg cataaaattg aatgctcaaa caccagctga aatagctgta tgtatagctg
    28381 ctgaacttat aaattgtaga gctaataagg aaaaataaac taatgaacac agggagtaaa
    28441 gatattgata ctttaaatgt taattttaga gggattgaaa taaaagcagt tttagtatat
    28501 aaaaatagaa aaaatatttc tataaaaata gatccatttg gcaaaataat tgtaatgagt
    28561 cctcctaaaa tatccaaaaa aataataaaa gatataatta ttgaaaaagg agactggata
    28621 cttaaaaagt cagaaaaata taaaggaaga gaagaagtat acaaacaaag aatgtttata
    28681 actggcgaaa aatttcttta tttaggtgaa gagtaccatc tagttataaa agaactgttg
    28741 aaagattctg tcaaaaaaag taactgtaga ataactatta acgaatatca aatagttgtt
    28801 cagacaaatg atacaagtac agattttatt aaaaaatctt taaaatcttg gtataagatg
    28861 gaaagtgaaa gaatagtatt agagagaata gattttctta aattaaattg tgaaataatg
    28921 aagcaattag ttccagcaag tgttaaggta aaagaacaaa ataagagatg gggaagttgt
    28981 acagctcaaa aaaatattta tataaactca aaaatatcta tggcaagatt agatgtaatt
    29041 gattatgtaa taatacatga gtttagccat ttagtacata tgaatcactc taaaaaattc
    29101 tatgatttag taaaatccat tatgcccaat tataaagata aagaaaattg gctaaaaata
    29161 aatggatata aaataataat ctgaaaacga ttattccaaa atataggcgt aaagtataaa
    29221 agaagtatta ttgtgaaaaa aataaataat ctgaaaattt taaaaaaagt cattgacatt
    29281 gtaaatgata gggaatataa tctatattaa caacaaaaca gaattaaaat ataaaattaa
    29341 aaaattaaaa gcaatgacag agacaacaat actaatagtg ttatccacag agaaccaatg
    29401 ttgctgagaa ttggtgttaa cagtagtata atgatcactc tggagctttt gtactgaata
    29461 tttttagtaa gtacaaacgt atgtcaacgt tacatgacta aggttaaggt aattaattac
    29521 ccgacctgaa aaaagagggg tagatgtatt ttttatatct acaaataagg tggtaccgcg
    29581 gaatataact ttcgtcctta taagtaatat ttatattgct tataaagatg aaagtttttt
    29641 tattttaagc gatataaata aatttaatcc atataaaatt aataaaaaaa taataaaaat
    29701 aaggagggat ttttatggaa aatactgtat atgctaaatt aaaccaagga atagattctt
    29761 ttttaagagt ggctatgact ctaagaagaa gagaggttga tatacaatca ataagtatga
    29821 ctgtagataa tatgaataat tcaggtataa aattaatagt aaatgaagaa aagacatctt
    29881 tagattctgt cttaaaccat atgaaaaaac tacatgatat aagagagata actgttgaaa
    29941 gaatgagaca ttaattaaat atattttata aagctaaaga taaatatgct tattttaaaa
    30001 taaaaaacta aagataaata ttaaataaga aaaatcttag attaaaatat aagtgtcatt
    30061 gaatttatta atttatcaca gttaataaat ttattagttt gttgtagcta ataaaaactg
    30121 aaaattctaa aattataatt gtaagattat ataaatttag aatttaaatc tgttgaataa
    30181 tattaaaaca atgataatga gtatgaattt ctaataaaaa taaatatcat aaaaataaga
    30241 aaaagtattg ggaggaaatg aaaatggcaa gaatgtatta tgaaaaagat gtggatttag
    30301 aggttttaaa aaataaaaag gttgcagttt taggttatgg aagtcaagga catgcacatg
    30361 cacaaaatct tagagataac ggtgtacatg taatgatagg tctttatgac ggaagtaaat
    30421 cagcacaaaa agcaaaagaa gatgggtttg aagttaagag tgtagcagaa gctacaaaag
    30481 aaagtgattt gacaatgatg ttaatgcctg atgaaaaaca aaagaaagtt tatgaagaga
    30541 gtgtaaagga taacttaaaa gaaggtcaga cattagcttt tgctcatgga ttcaatatac
    30601 attataatca agtacaacca ccagaatttg ttgatgttgt aatggtagct cctaaaggac
    30661 ctggtcactt agttagaaat gtatttacaa agggaagtgg agttcctgca ctatttgcag
    30721 tatatcaaga ctacactaaa aaagctacag agacagtttt agcatatgca aaagggatag
    30781 gagcaacaag agcaggtgtt ttagaaacta cttttaaaga agaaacagaa acagatttat
    30841 ttggagaaca atcagtactt tgtggtggaa taagtgaact tataaaattg ggatataaaa
    30901 cgcttgtaga tgcaggttat caaaaagaag tagcatattt tgaatgttta catgaaatga
    30961 aactaatagt cgaccttata tatgaaggtg gatttgaaag aatgagatat agtataagtg
    31021 acacagcaga atatggagat tatgtatctg gtaaaagggt aataactgat gctgcaaaac
    31081 aaggtatgca aaatgtttta gaggatatac aaaatggaaa atttgcaaaa gcgtggatta
    31141 aagaaaatga agaaggacgt gaaaacttcc taaaaactag agaagaagaa tataatacag
    31201 aaattgccga agttggtaga aatctaagaa gtatgatgtc attcttaaaa taaatatata
    31261 ttaaatggat tagtttgagg gaaagagtgg tgtatagtag tgcgtatgaa tggagcaaag
    31321 gtaattttag aatgtttaaa gaaagaggga atagacacaa tatttggata tcctggtgga
    31381 gccgtgatac ctctttatga tgctctatac gattattcag atgattttaa acatataagg
    31441 acatcccatg aacaaggttt agttcatgct gcagatgggt acgcaagaag tactaataca
    31501 gtaggagttt gttttacaac atctggtcca ggagcaacaa atgccataac tggaatagca
    31561 acagctttta tggattcttc acctatggtt gtaatttcag ggcaggtgcc aactagttta
    31621 ttaggaaaag attcttttca agaaattgac ataactggag caacattatc tatgacaaaa
    31681 cataattatt tagttagaaa cactaaagaa ttagttccta caataaaaga agcttttaga
    31741 gttgcaaatt caggtagaaa aggacctgta cttgtagatg ttccaaaaga tttattttta
    31801 gcagagatgg attttagtgg tgaggactat gatttatgtc aaatagatga ttatatggat
    31861 tataagagtg attttgatct agatgatgaa actaatatta agcttttaaa tgaagcaata
    31921 gatatcataa aagaatctaa aaagcctgta atatatgcag gtggaggtgt taaatcttca
    31981 gacagtgagg aaattcttga aaaatttgca actaagatag atacacccgt actaaataca
    32041 cttatggggc ttggaaatat agatagaaag aatgaactat ctcttggaat ggttggaatg
    32101 catggaagta gagaaagtaa tttagcactt tctaattcag atttagtgat agcgataggt
    32161 gcgagattta gtgatagagt gataagtaaa agttctgaat ttgctaaaaa tgcaaaaata
    32221 atacacatag acatagaccc atctgaaata agtaaaaata tagaatctaa tgtatctttg
    32281 gttggagatg taaagctagt ccttagttta ttaattgaaa gggttgaaag taagaataat
    32341 agcaattgga aagaagagat aaagacattt agaaagagtg agggtgtaca aacatatgaa
    32401 tttcatccac aaaatatact taaaaaaata aatgaaaaat atgaaacatt aaagaaaccc
    32461 actgtggtag taactgatgt cggtcaacat caaatgtggt ctgctaaata ctggaatttt
    32521 aaaggtaata aaagttttat aacatcagca gggttaggaa ctatgggatt tggtttaggt
    32581 gcagctattg gaactaaagt tggtaatgta gataaaaatg tagttttagt cactggtgat
    32641 ggaagtttta gaatgaactg taatgaacta gctacagttg caaattataa tgtacctatg
    32701 cttattttac tactcaataa tagaacatta ggaatggtaa ggcaatggca aaagttattt
    32761 tccaatcaaa gatactctca aactgacatt aatgaaaatg tggattatgt taaactcgta
    32821 aatgcatata atattgatgg atataaggta tccagtatgg aagaattagg aaaggcgcta
    32881 gatatgatag attttaataa acctgtattt ttgcaatgtg atatagataa ggattatgat
    32941 gtttatccta ttgtagcacc taatgatgca ttggaaaatt tgatatgtaa ctaaaactta
    33001 tactgaatat tgataaaatt ttttattaaa tttttattgg tattcagttt ttgttgttta
    33061 gagatagatt ggcatttttt attttctcaa ataaatcaat gactatataa ttaagaactt
    33121 attaaatttt aattatacaa tttggaatag tattacaact taagtaaata ataattttga
    33181 ataataattt acggaggtat tcatatgttt aaacacgata aagcattatt aaaagaagta
    33241 aaagtagaaa gaccaaatcc tcaatatgct gttttaatgc aagaacagtt gggtggtgca
    33301 aatggagagt taaaagcagc tatgcaatac ttgtcccaaa gttttagaat aaaagaccct
    33361 caaataaaag atttatttct tgatatagca gcagaagagc ttagccatat ggaaatggta
    33421 gcacaaacta taaatttatt aaatggacat gatgttgatt ataatgcagt taatacaggc
    33481 gaaatagaaa cacatgtatt aactggtcta tcaccagtct taataaactc atcaggagct
    33541 ccttggactg ctaattacgt tacagttaca ggggatttag tagctgactt actttcaaat
    33601 atagcttctg aacaaagagc taaggtagtt tatgagtact tgtatagaca aatagatgat
    33661 aaatatgtaa aagaaacaat agatttctta cttaatagag aagaagcaca taatgctcta
    33721 tttagagatg ctttaaataa agttaaagat acaggttcaa atagagattt tggagttaca
    33781 gaagattcta aattatattt cgatttgtct actccagggc caaatcacga tactaagata
    33841 gatattaatc ctccttcttt tgaaaaacct ttaaaaaaat aatttgatat tttttatgtt
    33901 gttttgtttt agtagttata aaaattattt attagaagaa ttaattatat gaaaaattaa
    33961 atatgtatag ttaaaaatgg gtatacactt attataagtg tatatctatt tgtttattgc
    34021 aaaacatata ataaaataac aaatgaggtg gtattttgga cagtaataga aaacctaata
    34081 atctaataaa tgaaaaatct ccatatcttt tacagcatgc ttataatcct ataaactggt
    34141 atagttggaa tgatgaggct tttaaaaaag caaaagaaga ggataaacca atatttttaa
    34201 gtgtaggata ttcaacatgt cattggtgcc atgttatgga aaaagaatct tttgaagatg
    34261 aagaagttgc tgaaataatg aatagaaact ttgtggcaat aaaagtagat aaagaggaaa
    34321 gacctgatgt agatagcgtg tatatgacag tttgccaagc tatgacaggt agtggtggat
    34381 ggccaatgac cataataatg acaccagata aaaaaccttt ttttgcggga acatatttcc
    34441 caaaatattc aaggtataat agacctggag ttatagattt attagagaat gtatctgaaa
    34501 agtggaatac aagcagggat atattaataa aatctggaga tgaaataata gaagctctta
    34561 aggatgattt tggtgtaaaa aatactgagg gtgatttatc aaaagagatg ttgagttcat
    34621 cagttagagt atttaaggct atttatgatg aaaagtatgg tggttttggt aatgctccta
    34681 aatttccaag tcctcagaat cttatgtttt taatgaaata ttatagtata gaaaaagaca
    34741 aagatgtgtt aaaaatggtg gaaaaaactt tagatggaat gtatagagga ggcctgtttg
    34801 atcatattgg atttgggttt tcaagatact ctactgataa aaagtggttg gctcctcatt
    34861 ttgaaaaaat gctatatgat aatgctatgc ttactatagc ttttttagat gcgtataaaa
    34921 taacaaagaa agagttgtat aaagaaattg ctataaaaac tatagattat gtagttagag
    34981 agatgaagga taaagaaggt gggttttatt cagcacagga tgctgatagt gaaggtgaag
    35041 aaggtaaatt ttatacattt aatcctcttg agataattga agttttgggt gaagaagatg
    35101 gaactttctt taataattat tttgatataa ctagtagtgg aaattttgaa ggcaaaagta
    35161 ttcctaatct tataaaaaat aaagaatatg agagacataa tgaaaagata gctgacctta
    35221 gtaaaaaggt atttgaatat agaaaagaaa gaacatcttt gcataaagat gacaagatac
    35281 ttacatcatg gaatgcattg atgatagttg ctttaacaaa ggcatatagt actttaaaaa
    35341 atgacatata tttagagtat tcaaataagt gtcttaactt tataaataat aatcttgtaa
    35401 atgagtcagg tagattatta gctagatata gagatggaag ttccgactat ttagcatatt
    35461 tagatgatta tgctttttta atctgggcgt atatagagct ttatgagtca acatttaata
    35521 tgaaatattt agaaaaggct ttaaatttga atgaaagctg tatcaacctt ttttgggatt
    35581 atgaaaaaag tggattttat atatatggta aagatagtga aaatttaata gcaagaccaa
    35641 aagatttgta tgatggagct attccatcag gaaattctgt tcaattatac aatcttataa
    35701 gacttgcgaa aattactgga gataatagac ttgaagaaat gtcatataaa caattaaaac
    35761 tgtatgtgga taatgtaaag agttctccaa ctggttacag cttttatatg ctttcattga
    35821 tgtttgaact ttattctact aaggaaatta tatgtatttt taaggaagat tctgatttaa
    35881 ttgcctttaa agaattgata agtaaaaatt ttataccaaa tgcaactttt ttagcaaaga
    35941 aatataatga agaaaacact attataggtt ttttaaataa ctatagattg aaggatgata
    36001 agattagtta ttacgtgtgt caaagtaata gttgtagtca accaattaat gatttacaaa
    36061 aattaaaaga tatgatttta ggagtagaat aatcataata gcgaaaaagg agatgcttta
    36121 aaataaaagt ctaatcatct cctttttttg tataaaaaac agaaaaagag ttcctaagaa
    36181 cacctaatct atgtaatgat tgttttgtta aaaaataaaa atgacattat agttatataa
    36241 aatattgtac tataaaaaag tggtattata gatgcgatag tattaatctt ttttatttac
    36301 cctatttctt ctttttacaa attcttcaag tgcttcagat ttaattttat ctatttcttc
    36361 atattccata aaattagcat cttcttcaaa gccatcttgt tcttcaccat taaaacgata
    36421 catttttttt agtaaactcc ataaggtctc taattcatct ttggtaaatt cgtgaaatac
    36481 atctgccata aagtttattc cagttctact acatgtcacc ataacctttt ttcctaagtc
    36541 tgtaacttta acattaattg ctctcttatc atgaggactt ggaattacat caacatatcc
    36601 atttttttca agattagcaa ctagtctatt tatattttgt ttacttgtac ccatttttct
    36661 tgcaatatta tttaatgttg tttcttcctc tggtaaatga agaattgata aaatagtcat
    36721 atactgtctt gaagtaagta taccaaaata tttatctcct tctatttgta ttttgtttgt
    36781 aagggtaaaa agagttgcat atgtttgatt cattaaaaag agctctttta gttcatttga
    36841 ataatccatg aaatatatct cctttatttt tagatgttgt tttgtcgaaa acagaatatc
    36901 atgaattaat tctaatgtca atatggtgtc aaaatatatt aaagtattac ttttttatgt
    36961 aactattaat taattaaatt attgtacaat tttatgtaaa aacttctatg taccaatgat
    37021 aacttctatg aggaattaat aattcttaaa ttttttagaa agattttgac ttgaaaatac
    37081 ttgtaatata atatataaat taatatactg aataaaatca atctggaggg ataattatga
    37141 agtgtacaaa ctttactttc aaaggagagg aaggtttaga tatatataca tataaatggg
    37201 aagatgaaaa tataaaaaaa ccaaaggcag ttatccaaat tgcacatgga atggctgaaa
    37261 ctgcacaaag gtatgagact tttgccaagg tacttactaa aaatggttat atagtatata
    37321 tcaatgacca tagaggtcat ggaaaaactg caaagataat agaaaatgtt ggacatttag
    37381 ctgaaaaaga aggatttaga tgtcttgtag aggacatgta tactttaaca aatattataa
    37441 agaaagaaaa tgaagatttg ccaatttatc tatttggaca cagcatgggt tcatttgcaa
    37501 gtcaaagata tataatggat tacagtaata atttatctgg tcttatacta tgtggttcaa
    37561 atggaaagca aggaatcatt ctaaatcttg ctcatctgat aatcaatcgt gagattaaaa
    37621 agtatggaag acgttctaaa agtaataaaa taaataattt gatatttggt ggcgaaataa
    37681 taagaagaaa tgaaaagact aagtttgact ggttaagtag agataaagaa caagttgaaa
    37741 aatatataaa tgacccattt tgtggagtag tgtgtagttg tggctttttt tatgatttag
    37801 ttcaagggtt aaaagaaatt gaggataaag aaaacttaaa aaaagtgcca cttgatatac
    37861 ctatttacat aatatctgga gataaagacc ccataggaaa aaatggtaaa ggagtcttaa
    37921 gactaaggga tagatatata aaattaggag taaaagatgt aacttgcaaa ctttacaaag
    37981 atggaaggca tgaattgttg aatgaaataa atagagaaga agtttttgag gatataattt
    38041 gttggttaaa caataaaata gaaatattgt aataaaaaaa tataatgata tatttgcttt
    38101 aaatttattt atatataata tttgaaaagt ggattatgta tatgcaaagt agaaaagaga
    38161 gagcctagaa gtgatttttt gctataatgc catttattga ataggtgggt gttattataa
    38221 ataaattatt aacactcagt attattatca ttgtatatgg aatttatttt atttaaaatt
    38281 ccttgaaagt ttaaatatag taagttgtag taaagagaaa atctaaatat ttaaatgcta
    38341 tttaatgtga atctattaat taggttatac ttaaacttaa ttaatagatt ttatatttca
    38401 agccaatgag atagggtttt agattaaaat ataaccaatg gttaaattac agacattttg
    38461 ttaactttcc ctcgatttac tagtaaatat tttttttata tacttaaatt acaacagatg
    38521 tactagggag gtatatatgc aaattaaaat aggtaaagtc atacagcgtc ttagaaaaga
    38581 acgaaattta actcaagaac aattagcaaa gtttataggt gtgtcaacac cagcagtatc
    38641 taagtgggag agtggaaatt cttacccaga tatagaatta ttgcctttat tagcagactt
    38701 ttttaatgtg tctattgata agcttttaaa ttacaagatt gatttaagtg aagaagaagt
    38761 aatgaaaatt tataaagaat tagaatcagg ctttgctaga attgaaattg atttatcaac
    38821 agaagaacca aaagaagaat ttagacaaga cttagaatct gtaaaaaagc tttctaatat
    38881 gtatatagag aagtatccta aaagctattt attgaagcta aggatatgtt cgctgtatca
    38941 gatgtattca tataaatttg gtaagagtga acttaatgac agagtaaaag aaacaacgaa
    39001 tattcttgaa gatatagtga gaaatacaga tgatatccaa ataaaagaaa cagctcttat
    39061 tatattatca agcgcatatt gtatgttgga ggattatgaa aaggcagagt tgtatttaaa
    39121 tatgatacat aagtcaatag gggatacaag tgttaattta gctatgatat atttaaagca
    39181 aaatagactt gaagaagcag aaatattgct tcaaaataaa ttgtttagta atgtatttaa
    39241 tataagcatg gattgtaagg gaataattaa tgtatacaaa aatcaataca aggaattaaa
    39301 gaaaaaattg gagaatagaa attttaataa aaatgcaatt gagagagaaa tggagtatat
    39361 aaaaaataag ttgctggggt atgcaaatct ttctttagaa ataaaaaaaa tgctcagtga
    39421 agataaaggt gcatttttta gtatgtatgt ggattatatg gaattatctc taattttttt
    39481 attttttaac atgaaagaag aagcaaaaaa agccttatat agtctaaaag aaatattaga
    39541 aaaatatcct atacatgaaa gtttggatgt aagtcaaatg agattttttg ataaggtaga
    39601 gtctaaaaat ttatatactt ttaatatata tacaaacttg ttaattgtac ttaatgatga
    39661 cagttataat gagcttagag aagaaccaat ttttaaggat gtaattgaaa agattttaga
    39721 tatggaaaaa atgttgaaaa ataaagaata agtaaaaatt taatatagga cttaaagatt
    39781 aatcaaatta aaagaaagtg tttcaaaata aaaatttgaa tcaccttttt tgttggtctt
    39841 aaaccgttat ttagaaaaat agaggtttca aaatagaaat ctgaattatc tgtattatta
    39901 cacaaaaata gaaacctaaa tttataaaaa tagaataaag tttgttatat aaaatgtaat
    39961 tttgtctata aaatctcaca tgttttctta actttaagcg tgaaaaagag gatgtatcat
    40021 gaatttttta gttcatgatg catccttatt tgtatgaaat ccaatatatc tttattattt
    40081 aaacaatgga aaagagtctt atttctattt tgagacatct cttttattta attatgaagt
    40141 tttatacagt tcaataaata ggaattatat ttagaaactc atgacattat ttcttagata
    40201 gtgattaaat ttatcatatt ccattttaga taacttttct gggtaagaca ttacaatcag
    40261 gttatgccca ttgaattttt catggtatgg tggatgaatg tgttcataat tatttgtctt
    40321 atattttact ctttcataga acgccttgcg ataaattgaa atctcatcaa ttggaaggtc
    40381 aatttctaaa ataatagttt ttcctttctt atttaaaagc tctaacgctc tttgtccata
    40441 tctattattg cgcatttctg gaaaaatgca gaaatgttct acatagataa agtcatctgt
    40501 ttcccaacat aaaattatgc cgacaaactg gtttttatca taaattaaat tgaattgata
    40561 ttctttattt ttcaaaattt ctgcttgcaa agaagatttt ctttgttcat gaaatgggaa
    40621 actaatttta tataattcca tagccttgta atataattta ttttcactgg ttcttaaccg
    40681 ctcaaatttc actttactcc tcctaatcac gaaaattcca atttatttat gagttcattt
    40741 taccatagtc agtatttgca tacaatgtgt tttaagttga gtgtcatttc tttcttttat
    40801 ttatgcttat atctcataga ctaagagata attgcttaag acataactaa aaactattat
    40861 attaagcttt gataatctaa aaacagtata tttatggact tttctaggtc taaaagtaat
    40921 cttaataatt ttagaagtta caaaaaagtt acataaattt agaaagctat aatatacata
    40981 tataatataa ggttaaaact gtaatgaata atattaattt aaaatttgaa catggaagga
    41041 gattattatg gagaaaagag aaaagaggat aataatatca tctttattaa gtgtatcaat
    41101 tttaatgggt ttggtaagta tatattctat attaaataaa gaagacataa ttttaactgt
    41161 taagggtcaa gagcaaaaag tatcttcctt taagaaaaca gttgaggaac ttttggatga
    41221 acagggtgta aagtataatt ctgaagataa gattaatcca agtttagata cagaactaaa
    41281 agatgatatg aaaataaaag ttgttaaggt aactaaaagt aaaaaagaag agattgaaaa
    41341 aattccattt gatacaaagc atgtaaatga tagtaatttg ttaaaaggga aatctaaagt
    41401 ttatcaagaa ggtcaagaag gagaaaaaaa actagtctat aatttaactt accatgatgg
    41461 aaaattagtc aaaaaagtct tatcaaaaga agtaatatct aaggagccaa ctacaaaaat
    41521 tataaaatat ggaactaaag aaaaagtact aatagcatca agaggagcaa atataagagg
    41581 aggcaaacat atgaaagtgg ttgccactgc atatgcagga gatacaataa catctactgg
    41641 tacaactcca agatggggtg ttattgcagt tgacccacgt gtaataccat atggaacaaa
    41701 agtatatata cctaaactgg gtatgacttt tgtagcagaa gattgtggag gtgcaattaa
    41761 aggtaataga atagacattt ttatgaacag tgaaggaaaa gcttcaaatt ggggaaggaa
    41821 aagtatagat atatatctac attaaattag tgaatagaat aactttactt gaaggacaaa
    41881 aaagtataaa atatgaatta actaaactgt tagattattc ttaaaacata aaaatatatc
    41941 taagggggga taagatgaaa atagtctgct taggagacag tttaacgtat ggatttggag
    42001 tatcacgaag taattcatgg acaaacattg taaataaaga gactcgatta gaaatagtaa
    42061 ataagggtat aaatggtgat acaacaagtg gtatgttagc taggtttaat gaagatgttg
    42121 taaaaaactc tcctgatata gtttttataa tgggtggcac caatgatttt attgctggtg
    42181 cgggaaatga aattattaat tctaatataa tggctatggt gcatcagtca tattcaaaaa
    42241 atattatacc tataataggt ataccattaa aactagatat tccaaatgtt agggaagatt
    42301 ggagttgttt tactgatttt aatatagtat ctcaaaactt agaatcatat agttattgga
    42361 taaaaaaatt ttgtatgaca tttaatacta atttcgtaga tttttattca gaatataata
    42421 aaaatatgga actagaagga tataaaaaat tatattttga tgggttacat ccaaccaaag
    42481 agggtcatag aataatggca gacattttta ttaattcaat taataagtat atagaagagt
    42541 tatagattac attaaaatgc ttgtttatgc gtcagttgca ataaatacat acagtagaga
    42601 ggggtttatt atggattata ctaaaactta tgaagagtgg ataaagggtt catattttga
    42661 tgaagataca aagctagagt tggagaatat aaaaaataat gaaaaagaaa tagaggatag
    42721 attctataag gatttagaat ttgggactgc aggtcttaga ggaataattg aagcaggaac
    42781 gaatagaata aataagtaca cagttagaag agctactttt ggattggcaa actatatatt
    42841 agaaaacaca acaaaagaag aaacaagtag aggggtagta atagctcatg ataatagaca
    42901 caagtctaga caattctgta tagaatctgc aaatactttg gcagcatgtg gtataaaagc
    42961 atatatattt gatagtttga gaactactcc agaattatct tttgctgtta gaagcttaaa
    43021 tgcaatcgct ggtatagtca taacagcaag ccataatcct ccagaatata atggatataa
    43081 ggtatactgg gaagatggag cacaagttat gccagagatt gcaaatgcaa taacagagaa
    43141 agtaaatagt atacatgatt atagtacaat accaacctta acggaagcta ataaaaattt
    43201 ggtagttttg ttggacgaat cacaagatac taaatttata gaagcagtaa aaagccaaat
    43261 tataagaaaa gatttagtta aaaatgtagg taaaagcttt aagatagttt atacacctct
    43321 ttgtggaaca gggaatgttc caataagaag agcattgaaa gaagttggtt ttgaaaatat
    43381 aattgtagtt ccagaagaag aaaatccaga cccaaatttt gcagggcttg attatccaaa
    43441 tccagaagag aaaaaagctt taaatagagg tatattactc gcaaaagaaa aaggagcaga
    43501 ccttgtaata gcaactgacc cagattgtga tagagtaggt gtagcagtaa aaactactac
    43561 aggtgagtat gctttactta caggaaatca aattggtggt atgctgacac attatataat
    43621 agaaggatta aaagaaaata acaaattaaa agaaaatcct acaataataa aaaccatagt
    43681 tacatcagaa tttggagcag atatagctaa agcaaataat gttgatgtat taaatgttct
    43741 tacaggtttt aaatttattg gtgaaaaaat aaaattattt gaacaaaata aaaatagaag
    43801 ttatgtattt ggatatgaag aaagttatgg ttacttagtt gggactcatg ctagagataa
    43861 agatggtgta gtttcttcat tgttaatatc tgaaatggca gcattttact attcaaaagg
    43921 tataagttta tatgatggtt taatagaact ttataaaaag tatggatttt tcaaagaaca
    43981 gactatatct ttgactttaa aaggtataga aggtgtagaa aagataaaag aaataatatc
    44041 ttattttaga gaaaatcaaa ttgattatat aaatagtatt aaagtagttg ataaaaaaga
    44101 ttataaaaat ggtatagata atcttcctaa atctaatgtt ttaaaatact ttttggaaga
    44161 tgaatcttgg gtagctataa gaccatctgg aacagaacca aaacttaaat tttacatagc
    44221 tgtaaaagga gctagtgata ttgaagcaga taaaaagatt caaggtttga aaaagtatat
    44281 agatgacatg gtcgaaaaat taaaataaaa tattattatt ttataagata attttgtaat
    44341 aatatttatt tagctgaaaa ttataattta ctttcattga gtagaatatg gaaatgttag
    44401 tagaattgtt attttcagct tttatttgtg ttatttttac ttaaataatt atattataga
    44461 atgaatctga gtataattaa tattgtataa tgaaattaat ttgatagaaa aggggatatt
    44521 tatgtttggt atagataaga aattgattga atatataatt gcaaaatcca attacagtga
    44581 attaagttca aagtcagcag aagtatcttt cttcttaatg ttgtccatat ttcctttttt
    44641 aatatttaca ataagttcta tagcttatat accgattctt catttaaata agtatatagc
    44701 tttgtttaga aatatgatgc cagaaggtgc ttttgctgtg ttatcttcaa tcatagtttc
    44761 tgcaatagac aatagaaacc tgaaattttt agcagtcagt tttgtactta ctatgtggac
    44821 attttcaaga gcagtaaaag ctcttattaa aggaatgaat agagcctata aagttaaaga
    44881 aactaggtct ttttttaaaa ttttatctat atcattttta tttacaataa tgcttttggt
    44941 ccttattttt ttatctatga tatttttagt ttacggggaa aaaataggtt attttatttt
    45001 taatcttgta ggattggatg agatatttat aaaaatatgg gatattctaa gatacactgt
    45061 aggtataata acaataatag tgatatttac acttttatat aaatacactc caaataaaaa
    45121 gttaactatt aaagaatctg cgccaggtgc tatttttgct acttttgctt ggtttttagt
    45181 atcattttta tattcttatt atacaaatta ctatgctaac tatgaagtaa tctatggaag
    45241 tatagctgaa ataattgtac ttatgacctg gatgtatttt agtagttggt ctatcgttat
    45301 tggctatgag gtaaattcaa gattgtattt tagaaagata agacatgaaa tgttaaagta
    45361 aagtatttaa aataaaagag agtatttagt attataaatg taattgaatt aataaagaaa
    45421 tattgacatt taagttaaaa agtctagaat ttttctgggc tttttttatt tttagtataa
    45481 cttgacaaat tttatttaat gggatagttt taatttataa tcatctttga aaagatgact
    45541 attgataagt aaggtataaa attggtaagt atcaaaaaat atactaaata aaaattatag
    45601 tcctaatgag ttaatttctg tattttcaaa taatgcagta tttagtcatg tgtttttata
    45661 tgcgcctgta tttccaatta ccaatatatt agaataagct actgtaatta gatttagaaa
    45721 aaagcgacat aaataattat aaacaaataa taaattacat aaaattaaat ttattcacaa
    45781 gtatatctta taaaatatgt tataattaat agaaaattgt catataatta attaagtagt
    45841 attattataa ataacattga aaggtagtgg ttagaatatg gatatccata ataaatatgt
    45901 aaattttata aaaaatatac ctgtaccttt tttatattgt agaattgtaa agagacaaga
    45961 agatatagaa tatcgagtag aatatataag taagggtatg ggcaaagtat tacaattaga
    46021 agaaggtatt tgtgataaaa atatactaga tgtattgcct gtatttaagt ctaaaaaata
    46081 tttcaaagag ttgttctcaa atgaagtgga ttgtataaaa aggtacattc cgacacttaa
    46141 aaactggata aatataaaaa aacagataat aggggattca tacataattt tgtattttgg
    46201 taaaattgta tttgattata gacagataat cgattccttt gataaaaagg aaaaagtagc
    46261 ttatattaaa gacgaagaag gcatatatat agattgcagt gaaaatttaa taccaatatt
    46321 aaataacaac attaaaacaa cgaaagatat ctttggtaaa aatgatatag aagtatgggg
    46381 agagaataca ggaaaattat ttagagatga ttatagagga ggagtatcta gtaaaaaaag
    46441 atttttacaa aatctttttg aatatgaaga aacatttttt atggttgaaa aatatttttt
    46501 gtatgatgaa gacgaacttt taggtactat agggataata gataatataa tatatagtgg
    46561 ttacagtaat agaaattata actcaaaaga tttaatgaag atgatagaac actcaattcc
    46621 agagaatatg ttttataaag atgtgtatgg aaattatatt ggatttaatt caggtttttt
    46681 gaatttagct tgtatgaata aagaagaatt attagggaag aatagttata aaatatcaga
    46741 agaagaagct ttaataaata agatatttga aagtgataag ggtgtagttg aaaataaaaa
    46801 agtagttaca tttgagttaa atgtaagtat aaatgatgaa aataagtgta ttgagattac
    46861 aaaaaggccg ttttttgata gctatggaag tgttattgga ataattggaa cagcaaggga
    46921 tataagtaga agaaaaagat tagaagagga aatggataaa actaggatgg aattttttgc
    46981 aaatttatcc catgaactta gaacgcctat aaatttaata tcatcttcat tacaagtgat
    47041 agaaaaaaaa gaagcagatt taatagaatc aaatgatact ttaaaaagaa atttaggtat
    47101 aataaaacaa aatggaaata gaatactgag gttagtaaat aatgttatag actttacaaa
    47161 aatgcaatca ggatatttag attttaaacc agaagaatct gatataattg catttataga
    47221 ggagatatgt atgtctgtag ctgattttgc aagccaaaat aatatacaac ttacatttga
    47281 tacagaaata gaagaatttt caatgttatt tgattcagaa aaattggaaa gaataatatt
    47341 aaatttactt tctaatggaa ttaagtacaa taagaaagat ggaaaaataa atatattttt
    47401 atatgtgaaa gataatgtat ttaatatgaa aatatctgat agtggaatag gtataccaaa
    47461 agaaaaaata gataaaatat ttaatagatt tgaacagatt gacaatgaac tttcctacag
    47521 agttaaagga agtggtattg gactttcatt agtgaaatct ttggttgaat tgcatgaggg
    47581 aagtatatct ttaaaaagtc aacttggtat tggaagtgaa tttatagttt cattacctgt
    47641 tagaagtgaa aataatattg aaaaatataa tcataaaaga gaaatcagca atgaactaag
    47701 taaaaaatta gaaatagagt tttcggattt ataagtttaa atataaaaaa taaaatttta
    47761 aaaaagtatt gacaattgat ttagaagggt ttaaaataaa ttacaacata ataaataaaa
    47821 aggcgatgaa taggaagagt aaatctaatt cgattaccag agagaagagt ccattggctg
    47881 gaagactttt taaattagag ggattgaaaa ctacctagga gctactttct gaagtcatct
    47941 gcattagtag attttagtaa gaatagtcgt tagctgcgtt aaagtgtaaa gtgagttttc
    48001 atgatatatg aaaactaaat taggtggaac cgcgggaata atactctcgt ccttatgtta
    48061 taaggatgag agttttttgt tgtttaaaaa tataaacagt aatcataata attatagaaa
    48121 atataaaagc gatgaatagg aagagtaaat ttaattcgac tatcagagag gaaagttcac
    48181 aggctgaaag actttctaag tttgagaaat tgaaaactac ctaggagctg tggtctgaag
    48241 ttactttaaa aagttttagt aagactaacc gttaactgcg ttaaagtgta aagtggattt
    48301 tatcaataaa tgataaaatc aaattgggtg gaaccgcgag tatagactcg tccctttata
    48361 tagggatgag tctattttta ttgcaataaa agattgaaaa taaaaaaaaa tcggaaaatt
    48421 ataaatttag gaggaaaata aaatggaaaa taaagtgaaa attggagtac taggatatgg
    48481 agttgtagga agtggactta tagatataat agataataat aaagaaaaaa gaagtataga
    48541 aatagttgga attttagtta ataatttgga aaaacataag gataaaaaat attctaatat
    48601 aataactaat aatatagatg atatatttaa taaagatata gatatacttg ttgaagtcat
    48661 gggtggttta gaaccatcat tatcttatat aaaaaaagca ttaaacaata aaattcatgt
    48721 tgttacagca aataaagatt tgttagctga atgtggagat gagcttgcaa aattagcaag
    48781 tgaaaataaa gtaagtatta aatttgaagc ttcagtcgca ggaggtattc cagtattaaa
    48841 accaataata gaatcactag aaggaaataa tatagatagt ataaatgcaa ttttaaatgg
    48901 aactactaat tttatattat ctaaaatgta tgatgagaat ctatcttatg atatggcatt
    48961 aagacaagct caagaattag gttttgctga agcaaatcca gagtcagatg tattagggta
    49021 tgatgctgct agaaaactat caatattatc aactctagct tatgacaata gagtatattg
    49081 gaaggatgtg tatttagaag gaattacaga tatagatgaa aaagatattg aatatgcaaa
    49141 aaaattaaat tgtaaaataa aattgattgg tcaaagtaag tatgaaaatg ataaagtaag
    49201 tgcttttgtt agacctgttt tagtagaaaa agataatatc cttgctagaa tagacaatga
    49261 gttcaatgct gtcatagtga atggagattc agtaggagaa gtttcttttg taggtaaagg
    49321 agctggaagt ttagcaacag gaagtgcggt ttattcagat gttatagata taatagataa
    49381 tagagtttca agtatagatt cttttactaa agataaaata caagttaata aaatagttag
    49441 agaaaagtgt ggagcacttc ttagatttaa aaaatgtaat aaagatgaaa ttctaaatat
    49501 agttgagaat tgtttagtaa aattcgatat tttaaatgat gatgatgaac ttgctattat
    49561 ggtttatgct gattctgaat atgaaataaa caacagttta tgtctaataa aagataaagg
    49621 atattgcgaa aaaatgaata aaatgttgaa aataagttaa aaaagaaaaa ataagtttat
    49681 atgtaacata ttttgacgat tttaatacta tatagtatga gatgaaacaa aacatctcat
    49741 aaaaaattaa aattcaaggg agagatatgt tatatggaaa ataaaaaata tgcaaatggt
    49801 ggttattcag aagactggta tgaaagagga gaatctacag ctaaatggtt ccagaatgat
    49861 agagaagaat atgaaagagc agcatacgat gaagatagag aaagaagagg ctcaaactgt
    49921 ggatgttcag attcaggagg aaatagacct agaaactgtg aaagatttag aagagaagct
    49981 gagataagag aaagagaagc aagagaagca ttctgtgaat cttcagagag aaagaaagaa
    50041 gcactagcat atgaatgtga agctagaaaa ttatgggaag aagcagaaaa atactgggat
    50101 gaatattcaa aatacaacta taaaggaatc gaatatttag cagaagctgc tagattattt
    50161 gatgaaggta tggaatgtga agctagaaga aatggaaata atggaggaaa caataataat
    50221 tgttgccata aatgccataa atgtaattgt aactgctgta gaaaataaaa aaattcattg
    50281 acaaatcaat agttaaaata tatcatatta tgtataataa agagaaaatt cagaaaaaaa
    50341 taatgattag aataaattta agtatattta ttagacaaat agtgctcagt tagtgaggtg
    50401 agtacaatat gattaaactc ccatcctcta gcttttgata gagggtggga gtttttattt
    50461 attgatatat cttaaatgag gataatattg taaaataaat gagtatgaga ttgtaaaatt
    50521 aggaggtaaa aaatgaaaag tattaaaaca tcaagtatga aagaaaaggt agatgaaaag
    50581 atattaagag agcaagtaag ttctataata gaagatataa gaaataataa ggatgttgca
    50641 cttaaaaaat ataatgagaa gtttgataga aatacaagag atgaatttag aattactaag
    50701 gaagaaataa aggaagctta taagcatgta gatgacgaat ttataaataa cttaaagatt
    50761 gctgccaaaa atataagaga atttgctaaa gctcaaaaac taagttttga aaaccctttt
    50821 gaaaaagaaa tttatccagg tgtaatctta ggtcaaacta atattccaat agagtcatgt
    50881 cttgcatatg ttccaggagg tcagtatcca ttgttttcaa cagctcttat gcttataata
    50941 cctgcaaaag tagcaggagt aaaaagaata gtggcatgtt caccaactat gaaaaatact
    51001 gaaaagataa atcctaaaac attggtagct atggatatag caggtgctga tgaaatatat
    51061 gcaactggag gagttcaagc tatagcagca tttacatatg gaacagaaaa gattaatcca
    51121 gttgacataa ttgtaggacc aggaaataag tttgtaactg aagctaaaag acaatgttat
    51181 ggacaagtag gaattgattt tgtcgctggg ccaagtgaag ttcttataat agcggatgaa
    51241 acttcaaatc cagtttatat tgcagctgat ttattagcac aatgtgagca tgatttaaat
    51301 gcaagaggaa tattattgac aaatagattg gaagtagcac aaaaagttga aaaaaatata
    51361 gaaagtatgc taaaagattt gccaacaaag gacatagcat atagttcatg ggaaaataat
    51421 ggagagataa tattggttga tgatatggaa gaagccatta aaataagtaa tttttatgca
    51481 ccagaacatt tagaagttgc agtaaatgag tataatgata tttgtgatag attaactaac
    51541 tatggttctt tatttattgg aaatctttct gctgaggtgt ttggtgacta tgtttcaggt
    51601 accaatcata cattaccaac acttaaagca tcaagatata ctggtggtgt ttgggttgga
    51661 acttttatca aaacttgtac aaagcagata tttaatgaaa aagctataca atcattagca
    51721 cctgtagctg aaaagctggc aaaagaagag ggattatatg cacatgcaaa ggctgctgag
    51781 gttaggttta aaaagtagta aaaaatttta ttttggcagt cgagatttag tattagactg
    51841 agataaagaa aacgctgaga acctgaataa atactatatt ttgtgagcct cggcgtttct
    51901 tttatatctg tatataatag gataatacta cctgtgtgtt taaatgctaa cttaatattt
    51961 cttttctaaa taatgtttat gaaatagtta atatttttag ttaatacttg aaaaaaactt
    52021 ttgctaactg tgcaaattca tctgcatttg tcaatatagc agggtgtcct ccctgactaa
    52081 aaatgtgaat acttgctttt gaaataaaag ttgccatttg cttgtactct tcttcaagat
    52141 tatgacgaca catttcgtct tccttacttc ctgtaaataa aattggcatt tctaatttac
    52201 acaattcttt atgaaataaa gggcgtttct tgtttgcaca ttgcaataga gcttttgtat
    52261 caagattaac aacattctcc caatcttttc catgacacca ttcatagaat tttcgtgctt
    52321 gaatatcttg ctttgatttt tcccttccag tgattagatt atctatgaag ttatcattaa
    52381 gagtacgtcc atcaaagcta tctgctataa ttgcttcaac taaatcggga cgttctaatc
    52441 cagtattaac agctgcccat gctcctccac ttgttccaat taagccaact ttaccacaat
    52501 tcaaatgttc aatcagtgct attgtctgta aggcttcatc atgccatatg tcaggagaaa
    52561 attgagaaac tctatcagac tgtccattac ctaaaaaatc aattaagata catctaaaat
    52621 tttctacata taatggcaca agtgctttaa acatattaga agaaccagta ttaccatgca
    52681 ggaaaattat cggtttacct tgtccatatt ctttataaaa acaagaatta ccttgatact
    52741 gaaaatatga catatatttt cctccttttt atttgttaag ttaattataa caatataggt
    52801 atgaatgaaa aacctcatgt tctttcttag aataaaaatg tgccacgcat aaaacgtgac
    52861 acatttctaa ttataaattt tgctgtttaa gtattctttg tatgcttttc tctgtcaaaa
    52921 agtatttctc tgataactgc ttgatactca ttccattttg gaaatttata cagatttgag
    52981 aattacgaga agctaagact tgtttggtgt ttgtgttttc accccaatgc tttttgtgct
    53041 cttgcttttt gggaatataa atcactttac catctatata ttcttgcact tgctcaatca
    53101 gttctttagg cagtaagtca atcgaatttt gatagctcat tttgcacctc ctaaataatt
    53161 actctttagg attagcaaag gctactgcta ctcacaatta aaaataaaat tttttattat
    53221 gtacaatagc ctttgctatg cacaagttcc aattcccata aactaaatac tcctttctgg
    53281 tttgaaaaat tcatctgaac attgatttcg attttaagat agagttcaat gacaaattta
    53341 catttttatt atatatattc agatagataa ttgcaactgt ctttgtatga ggatatttta
    53401 ttatagtcaa tactataata tatatttata tcatcaaact aatatgaaca gttgaaagga
    53461 atatgaacaa taaaacttag tcaggaagaa taattatgaa gcagacaatt gagaaatttg
    53521 attttaaagt tttattgaaa atttattgac aaatttaact tgtaaatatt atactaaact
    53581 taataaataa agtttataaa gtaaggtgtt gtctatgaaa aatatagttg gaaaaccgca
    53641 aacgataaaa aaagtaaatg aagatttaat aaaaaacatt ataaaaaatg aaggtcctat
    53701 aacaaaacca gaaatttcaa gcattactga attgagttta gctacagtta ataagattgt
    53761 agagcaatta gctttgaaaa atgaagttaa agtaagtgga ctaagtgaat ctactggagg
    53821 aagaagagct caattatttg aaataaatgc aaacttagaa cacataatag ctttatatta
    53881 ttatagaaat tgttgtatag gggtagttgc caatttatta ggtgaaataa tttatcaaga
    53941 agaatttaat ataagaatgg atacatatga aaacgttaac caagatactt tttttgttat
    54001 agatactcta ataaaaaagg aaaaaggaaa caatataagg gctattggaa ttggtgtccc
    54061 aggagttgta aaaaaaggtg tagttaaaaa tataccaact ataaaaagtt gggaaggtat
    54121 aaatttagaa aatttaataa agagtaagta caatactaaa gtgtttatag aaaatgatac
    54181 aaatattact actattggga tttatcaaaa acagtataaa gacaaatata aaaatatggc
    54241 tcttatgtat ttagaagatg gtattggttc aggtatagtt ataaatggtg aattgtattt
    54301 aggttctaca aattttgctg gagaattaag ttatctaaat atagaatttg gtaagtataa
    54361 ctctaacaac ttaaatcttg aagattatat tatgagttta agaaaaagat atttagaaag
    54421 taaagataat aaatttaaga aagaaatttt atctataata tcaaacttta taaggactct
    54481 tgtatgtgtc ctaaatccac aagctatgat tatacagtgt agtatattaa ccaagagtga
    54541 catggagttt atagaaaaag atgtaagtaa taatgttgga gaagaaaatt ttcctaaatt
    54601 aataaaagta gagtcattga gagaaagaag tataaatgga gtaattagta tgtgtttaaa
    54661 agaaactgac tatcaatatt ccttatctaa taaaaaagga ggatattaat gtgaaatatt
    54721 tggtttcaat agatggaggg ggaacaaaaa ctaaattttg tgtaagtgac ttagatggaa
    54781 acatacttaa agaacatacc actggttcaa ctaattataa gtcagttgga attaaaaaaa
    54841 catatgaaaa tattaataat ggatttaaaa aaatattaaa agatttatat atcgattatg
    54901 acgatattga gtacactgta tttggtatat ctggttgtga ttctcctaat gattataaga
    54961 ttataatgga tgaaatatta aaaattggga ttaacaaaga aaaaatatat ctggcaaatg
    55021 atgcagtttt agctttttat gcacaagctg attcccctgg tttagtaatt gtggctggga
    55081 caggttcaat tatactggga attaaagaag atggagaaat atatagagtt ggtggatggg
    55141 ggtataattt tagtgatttg ggttctggat atgatatagg gagaaaatta ttaaagaaag
    55201 tattgcttta ttgtgatgaa tgtcatgagt atagtgattt atttagttgt gtcttggatt
    55261 tctttggagc aaatagtttt gaacaacttg catatatgat tactgatata aacgataatg
    55321 ttgaaatagc aaacttagct tcattagtga ttgattgtgc cgaacaaggt gataaattgg
    55381 ctattgaaat attaagagaa tcatcaactg aactatctaa attagctcaa gtaatattga
    55441 gaaaaatatc taatccaatg aaaatggata aaagcgaaat aaatatagtt ttgtctggtg
    55501 gtacattaaa taaaactgta tatgctcaaa tgttaatgaa taatttaaaa acagaaaata
    55561 cagataaaaa tttaaaattt atatctcaag aaaatcagcc agtatatggg gggataagac
    55621 ttgctatggc attagctaat aggagggtta agcatggata gaaaaaaggt aatagtacaa
    55681 atttttactg gaggttttaa ggctaaagaa ataaagttta atgatataaa atgtaaacta
    55741 ctagaattat tggactgtat tgatatagaa aaggttatca tggtatggag tgtagatgaa
    55801 gaattatatg tagaaactaa aaaactatta aataaatata atgttgaact atatctttgg
    55861 ttgccatgtt tttctgaaat aggattactt gaaaaaagta atttactaat tgattatatg
    55921 gggaaggaag tcaagggcta tgctttacaa gaggatgaaa attttgaatt ttattgccca
    55981 aataataagg aaaatataaa aaatataaag aaaatatata gtacttattt tagtgatatt
    56041 aaacttgatg gaattttttt agataaaata aggtatggtt ctttttcgaa taaactaaat
    56101 ggtgttttta attgtttttg taaagattgt ttaaatatat atgaaaaaaa taatattgat
    56161 aaaaagtcgt taatgagaga aatgaataat gtgtctaagg gagttataga taatgaagat
    56221 actccatttg gtataacaga atacattaat ggaaaataca aatttaaaaa taaaatatgg
    56281 gaagattttt ttgaaacaaa aaatcaaaat atatacaagt cattattaga gataagtagt
    56341 tattttaaaa gtaagggatt gaaaataggt atagatactt tttctccttt tatttcttac
    56401 tttacaggtc aagatttaaa aaaattacaa gaagtagcag attttataaa accaatgatg
    56461 tatagaacta caaaagctcc agctggttta ccatttgaat ttgaaaggtt tattgatgaa
    56521 tccatacata agaataaaga gattggaaaa agaaatttct tagatatttt aggaattaaa
    56581 gagtatgaag gagatgtata tcctatagaa tttgtactag aggaaatcga ttttatgaca
    56641 aggaatctta ataaagatat atatgtagga gttgaaataa ataaaaagga aattatagct
    56701 cctgttacac ctaagtacat aagtgaaaat atttcaaata taaataagac aacagtaaaa
    56761 ggatatgttt tatcttggga tttgttatca gcaccaaaag aaaatattga tgaaattata
    56821 aaatggtttc ggaattagtg aggtgatata gtgagtaaga tattagaaat gcaacaaata
    56881 tataaaagtt ttggaaaggt agatgtttta aaagggataa attttgagtt agaaaaggga
    56941 gaagtaagag ctcttttggg agctaatgga gcaggaaaat ctacacttat taaaatttta
    57001 ggaggagttc attctcaaac taaaggtaaa gtaattttga ctggtaatga aataatgttt
    57061 aaaaattcac atcattctaa agaaaatggt attagtataa tttatcaaga attaagcttg
    57121 ataccaacgc ttacagtact tgaaaatatt tttcttggta gagaaatttt aaaaggaagt
    57181 gtgtttttaa acaagaaaga catgcttgag gaatatatga aaatttgtga ggattttgat
    57241 tttaatatag acccacatac agtagtttct aatttaagtg tagcaaacca acaaatggtt
    57301 gagataatga aagctgtttc atgtaattct gaaattatca taatggatga acctacaaca
    57361 tcacttacta ataatgaaaa agatgggcta tttaaaataa taagtagact aaagtctaaa
    57421 ggtaaaacaa tagtctatat ttctcacata ttagaggaag tttttaaagt atgtgatagt
    57481 gcaagtataa tgaaaaatgg aattatgatt ggaacttatg atgtagagga tttaactaaa
    57541 ttaaagataa ctcaacttat gacaggaaat gataatcaca aacttattga gaagaaggat
    57601 tatacatttg caaaatatga agagccacca gtgctagaag taaagaatat aagctggtct
    57661 aacaaaataa aaaatgtttc atttaaagtt tatagaggag aagttgtagg tcttgcaggt
    57721 cttgtaggtt caagaagaac tgaaattata aatttgatat ttggtataga taataaagat
    57781 agtggagaca tttttatcaa tggtaaaaaa gtagacataa cttctcctaa ggttgctata
    57841 aaaaacaaaa taggattgat tcctgaagat agaaaaaatc taggattaat tttagaacaa
    57901 gctatataca caaactcatc atcagtacaa attgataaat tcaagaaatt tttgtttata
    57961 gatagaaata aagaaattga gttttctaaa aaaggtgtta aggaattagg aataaaagtt
    58021 agtgatgtaa agcaagaagt aaaagagctt agtggtggaa atcaacaaaa agtagtagtt
    58081 tctaagtggt tagagaaaga tttagattta ataatatatg atgagccgac aaagggaata
    58141 gatattgctg caaaagaaga tattttcaat acaatcaaag aattttcaag tgaaggaata
    58201 ggagtaatat ttatatcttc tgatttagaa gaagtaataa gagtaagtga tagaatttta
    58261 gtaactagag aaggttctat tgtagatgat ttaaaaaatg agaatataca ggttcaagat
    58321 ataatgaaca gtatatttaa tgtataaaaa atgaaaatgg aggactgaga tgaagaaagc
    58381 ttttgagaag ttaaatttaa gagattatgg agtattatta ggttttttag ctttatgtat
    58441 agctataagt attgcaactc catcattttt aggtaaacaa aatatactta atcttttacg
    58501 acaatcttct ataattggaa taatttcagc aggtatgact tttgttataa tatctggaaa
    58561 ctttgatata tcagttggag cagtagcagc tcttgcaggt gctataacaa tgaaatttgc
    58621 gactggtgga actaatttgt ttgcatccat gctcttaggt gtagcgattt gtgcagtaat
    58681 aggattaatc aatggtatag tagttgcaaa gataaatgta ccatcattaa tagcaactat
    58741 ggctatggtc actattgtaa gaggattgct gttgatgctt acaggaggat atccaattac
    58801 tgaaaatata ccaatacttg attacattgg aaatggatat ttgtttaata taccaatacc
    58861 agtagtaatt ttctttatag tggtgttagt ttcatttatt gtacttaata aaactaagtt
    58921 tggtagatat gtttattctg taggagggaa tcaagaagca agtaaactta atggtataaa
    58981 tgtagattct cacaaagtga aagtgtttat tattaatgct gtacttgcag gaatagctgg
    59041 aatcgtacta acaggaagac ttgggactgc aactgctatt gcaggtgaag gatatgatat
    59101 ggatgcaatt gcatctgtag taataggagg tacatcagtg gcaggaggtt ctggttctgt
    59161 acttaaaact gttataggag tattacttat gagtgttata aacaacagtt ttaatcttct
    59221 tggaatagat gtatatttcc agtacatatt taaaggatta ataattttag cagcagttgg
    59281 atttgattct tatagcaaga aaaaacttgc ttcaagataa aaaataaggg ggattttttt
    59341 atgaaaaaat taatgaaaca tttagcattg ttgttatcac ttgttatgat atttggttta
    59401 gttggttgtt caaatggtgg tgacaaagaa aaaaatggag aaaagaaaat agcagtatta
    59461 ctaccaggtt caacaggtta ctttgtagca actaaacaag gtatagatgc aaaatctaaa
    59521 gaattaggtg taagcgtgga atatgcagat gctcaatggg atgctagtaa acaattatca
    59581 caagctgaag attttatggc taaaggggta gacatgattg cattatgtgg agttgattct
    59641 gctgtaagtg agagaatagt taaagctgct aatgattcag acgtccctat agtagcattt
    59701 acaaattcta taggaagtaa cccaactgga gaatttaaag gtttagttac atatatagga
    59761 caaaatgagg aggaaacagg agcactaact ggaaaaattg ctaaaaactt attaggagaa
    59821 actggtggga aagctgtatt aatagaagga gtaccaggaa ctactccaca agtattaaga
    59881 aaaaaaggtc ttgaaaaaga attaaaagat agtaatatag aaatagttta taatcaaact
    59941 tcaaattggg agaaagagca agctttaaaa gtaacagaag atttaattca aaagaaaact
    60001 gattttaatg ttataatatg tcaagatgat aattctgcta caggtgcagg tcaagcttta
    60061 aaagatgctg gtcttaagga taaagttaaa gtcataggtt tgggtggaag taaagatgga
    60121 ttaaaagcta taactgatgg gttaatagat ggtacaactt atatgtctgc tgtagaagaa
    60181 ggtggattag tcatagaaaa ggcatctaaa ttccttaaag gtgaaaaaat agaacctgtt
    60241 acacaaatta aacaagttga agttaacaaa gataatattt cagagttcaa gggtgaatgg
    60301 taaattgtca tagataataa ataagatttt tagagttact ttagaaacta tataaagtaa
    60361 ctcttttttt aatttaattt agtgataaat tattgaatag tatttctaaa caaataaaaa
    60421 attaatataa acaaagactt aattatacta aattataagt aaaactaata taaacttatg
    60481 gaaaaaagga aaacgtctaa agtattggaa ttactatagt gtaggtgtgg tattaaaaaa
    60541 atataaaaaa acataaaaaa attgttgaaa aaaatataga aattttgtat aattaaagat
    60601 ttgaaaagtt cggtatacaa agccaattct tttgtatata atatatataa attcagaaaa
    60661 aggaagggat atgtatggcc aggcggttat ttttagaaag gattggactt atatttttag
    60721 gttcagcaat attagcattt ggagtttata atttttatta tttaaacaac ataacagaag
    60781 gtggagtgtt aggtatttta ctactgttaa aaaatttatt caatatacaa ccagcaatag
    60841 caaatgttgt aatagatggt ttactacttt tagtaggata taaatttttc ggtaaaaaat
    60901 tccttatata ttcaatagta gcttctataa ctttttcagt gttatatgac ttatttgaag
    60961 ctataggacc tctagtacca caatcacaaa atatgctttt atcaactatt ttggcaggtg
    61021 taactgttgg aactggtgta ggtatagtag taaaagcagg ttgtgcatca ggaggagacg
    61081 atgctttagc attagtaatt tctaagacta catctttgaa catagggcaa gtttatttag
    61141 caacagatgt tattgtattg ttgttatcat tattttatct atcagcgttt gatatctttt
    61201 attctttgat tgctgttaca attagtggca aggtaattga ttttatttat tatcatggta
    61261 aaagtttgga tatggatata agtaatgata tagttccaga atgttaatat aaattaaata
    61321 actttagatt ttattagggg tggcagattt gccacctttt ttatgtctaa atctttatag
    61381 aaagtataat cccatctagg tttttgcaaa tctcaaatat agaattatgt tggaatgact
    61441 gggaatacga ttgctagatg tgcattttaa aaacccaatt ttatatttat gaaatactaa
    61501 tcattaatgg atgtttctta atcctatctt tatacctaaa atgataagat aaatgaagta
    61561 gcaatacaaa actaaaattt gtaaaagaga ttaaattaaa tggaggagct aaaatgttgg
    61621 atatagttat gatagcattg ttattcatag gatttgtttc catgaagtta cttgctgatt
    61681 ggtgtgggaa acaaactgag aaaaaataat gtaatgtatg gagggattac ctatgtggtt
    61741 tctggcagtt gtaattataa tgttaataat atatttggta tatgcgctta ttaatcctga
    61801 aaaattttaa acagtataag gctaataagt aagttgaatt gggggaaaca atttttatgg
    61861 tgcagatagt aatagtgtta gcgattttta tgattttagt aatacctatg ggcaagtatt
    61921 tatatcatat agctactaat caaaaaacat ttggagatag actatttgat aaagtggaca
    61981 attttatata taaggtatgt agtatagata agaaaaaaga aatgaactgg aaacagtatg
    62041 cattagcttt attatttaca aatgcagtta tggtatttat aggatatatc atacttagaa
    62101 ctcaaagtat gcatattttt aatccaagtg gaattaaaag tatggaacaa ggactatcat
    62161 ttaatacaat aataagtttt atgacaaata caaatcttca acattattca ggtgaatcag
    62221 gactttcata ctttagtcag atgacagtga taatatatat gatgtttaca tcagcagcaa
    62281 caggatatgc ggctgctatg gcatttgtaa gaggtctagt cggtaaaaag aaaacattgg
    62341 gaaattttta tgtagattta attaggataa caacaagagt acttttacca ggagctttaa
    62401 ttattgggct tatattagtt acacaaggag taccacaaac ttttgctggg acagaaacag
    62461 tgactactat agaaggaaag cttcaagata tagctagagg tcctgtggca gctcttgaat
    62521 caataaaaca tttaggaaca aatggtggtg gattctttgg ttcaaattca tcacacccat
    62581 ttgaaaatcc aacaataata tcaaatatag tagaaatatt atctatgatg atattaccag
    62641 gagcttgtgt tgttgcattt ggtcacatga taaagaataa aaaacaaggt tgggttgtgt
    62701 ttggcgcaat gtcaatcata tttttaatag gtctagtagt gtgctttaaa gcagaaagtg
    62761 caggaaatcc tattttgtca caattagggc ttaatcaaag tatgggaagt atggaaggta
    62821 aggaagttag atttggtata gcacaatcat cattattcac aacagtgact acttccttta
    62881 cgacaggtac agttaataat atgcatgata cactgactcc tttaggagga ttagtaccac
    62941 ttttaaatat gatgctaaat gtagtatttg gtggtaaagg cgtaggtctg atgaatatgt
    63001 tgatgtacgc tataatagca gtattcttat gtggattaat ggtaggaaga acaccagagt
    63061 ttttaactaa gaaaatcgaa ggaaaagaaa tgaagcttat tgctttactt attatattac
    63121 atccactttt aatactaatg ttctctggtc tttcagtagc aataccagca gggcttgaag
    63181 gaatttcaaa tcctggattc catggattat cacaggtatt gtatgagttt gcatcttcag
    63241 cagccaataa tggttcagga tttgaaggtc taggagataa cactatgttt tggaatataa
    63301 caacaggtat agttatgttc tttggaagat atgtgtctat tatagtacta ctagcaatat
    63361 caagtttgtt agcatctaaa aaagctgtaa atgaaagtat aggaacactt agaacggata
    63421 attttacatt tacaatagtt ttagtacttg ttgttttaat tgttggtgct ttaacatttt
    63481 tcccagcctt agcgcttgga cctatttcgg agcatctagt gttgtggcac taaaaaattg
    63541 ggagggagta aagttttatg gaaactaaaa aaacaaagtt tattacaaaa gatattttca
    63601 aaacttccat tatagaagct tttaaaaaat taaatcctaa atatatgatg aaaaatccag
    63661 ttatgtttgt tgtagaaatt ggatttatag taacattgat acttacaata gtacctagtt
    63721 tgtttggtga tgaaggcaat aacttaagag cttataatgg gattgtaaca ataatcttat
    63781 ttataacagt cctttttgca aattttgctg aagctgtagc tgagggaaga ggtaaagctc
    63841 aagcagatac acttaagaaa actagaaaag atacagtagc aagggttata gatacgttag
    63901 gaaatgaaaa aatgataagt gcaagtgagc taaaacttgg tgatattgtt ttagtaaatg
    63961 ctggagaagt tattccaaat gatggagaag ttatagaggg tatagcttct gtggatgagt
    64021 cagcaataac tggagaatct gcacctgtca tgagagaatc aggtggagat ttcgcatctg
    64081 ttacaggtgg tactacagtt gtaagtgact ggttaaagat aagaataaca acaaaaccag
    64141 gagaatcgtt cttagataaa atgatagctc ttgtagaagg tgcttcaaga caaaaaacgc
    64201 caaatgagat tgctttaaat actttgttag tagggttaac acttatattt atggttgttt
    64261 taatatctct ttatccaatg gcaaactatg caggtgtaaa gattccaatt tctactatga
    64321 tagctctttt ggtatgttta ataccaacta ctataggtgg attgttgtca gctattggta
    64381 ttgcaggtat ggatagagta actagattta atgtaattgc aatgtcagga aaagcagtag
    64441 aagcttgtgg agacgttgat actatgattt tggataagac aggtacaatt acttatggga
    64501 atagacttgc atcagaattt atagcagttg gaaatgcaga ttcaaaagat ttaataaatt
    64561 attctgttat gtgttcatta aaagatgata caccagaagg aaaatctata gttgatttag
    64621 gtatgaaatt aggttcaaca ggtaagacaa aagaggcaga ggaagctgag tttgtagaat
    64681 tttctgcaca aactagaatg agtggtatta acttagctga tggtagagct ataagaaaag
    64741 gtgcttatga tagcataata aaaagagtaa aagaatctgg tggtacagtg ccagaagatt
    64801 tagaagaaaa tgtaaatcga gtagctaaac taggaggaac acctttagta gtgtgtgtag
    64861 ataatgagat atatggaatt atctacttaa aagatacagt aaaatcaggg cttgtagaaa
    64921 gatttgctag acttcgagag ataggaataa agacaataat gtgtacaggg gataatccct
    64981 tgacagcagc tacaattgca agagaagctg gagtagatgg atttattgca gaatgtaaac
    65041 cagaagataa aatagatgca ataaaaaaag aacaattaga gggtaaaata gttgcaatga
    65101 caggtgatgg aacaaatgat gctcctgcac ttgctcaggc agatgtaggt cttgcaatga
    65161 atagtggtac aacatctgca aaagaagcag caaatatggt ggatttagat tcagacccaa
    65221 ctaagatatt ggaagttgtt gaaataggaa aacaactttt aataactcgt ggggctttga
    65281 caacatttag tatagcaaat gatgttgcaa aatattttgc gattataccg gctatattta
    65341 ctcttgcaat acctcaaatg gagatattaa atgtaatgaa actttctaca tcatttagtg
    65401 cgatattatc agctttaata tttaatgcta taattatccc atgtttaata cctcttgcaa
    65461 tgaagggagt aaaatataga cctatgaaat cacaagctat gttaatgaga aatatgctta
    65521 tatttggtct tggtggagtt atagtaccat ttttaggaat aaaattaatt gatttattga
    65581 ttacaccttt agtaatggtt cttaatttag gttaataaat ggaggatata aaaatgaaaa
    65641 cattaaagcc agcattactt gtaagtattg tattgttagt tgtttgtgga cttgtatatc
    65701 cacttgtttt gacaggtgta agccaagttg catttaaaga taaagctaat ggaagtatga
    65761 tagaagtaaa tggtgtaaaa gtaggttcag aacttattgg tcaaagcttt acagatgcga
    65821 gattctttaa gggaagagta tcatcagtaa actataatac ttatacaaaa gaagatttag
    65881 taccagataa agatggaaac acatcttatg gaggtgtatc atcagggtct tttaattatg
    65941 gagctacaaa tccagaactt catgatagag tacaaaaaga tatagaaaag tttttaaagg
    66001 ataatccaac tgtcaaaaga gaggatatac caacagattt acttacagca tcaggttcag
    66061 gacttgaccc taatataagt ccagcctctg caaaaattca gataccagct atagcaaaag
    66121 cgtctggaat atcagaaagt aaattacaaa aaattgtaga tgataatact tccaaaaaac
    66181 tttttggagt tttaggtgaa gatagagtta atgtactaaa ggttaatgta gaggtcgcaa
    66241 aaatattagg tcttatatag tattttgtag aattttagta acaaaatatt actcaagatt
    66301 taatttaaag gttaaatttt aaagagtgaa aatcgataat gattttcact ttttttattt
    66361 gaatattact aatatttgga ataaagtgat tgtaagtata aaatccaaaa aaaggttgca
    66421 ttatcaaaat gataatacta taatatattt atcgttatca atttgataat agatttggac
    66481 atataggagg aaatagtatg ttatataata acgcattaga gttgatagga aacacacctg
    66541 tagtaaggct gaataattta ggctgtacta atgggtgttc taacatatat gtaaaattag
    66601 aaaaagtaaa tccagcagga agtataaaag atagagctgt ttatgaaatg ttagagggct
    66661 tagagcaaag aggagaatta aaaaagggag atgtactagt tgaagcaact agtggaaata
    66721 ctggtattgc attatctatg ataggaaaat taaaaggata tgaagtagta atcgtaatgc
    66781 ccgaaacaat gagcgttgag agaagagatt taatgaaggc ttatggagca aatttggtgc
    66841 ttacagatgg taaagctgga atggcaggtt ccatagaaaa agcaaatgaa cttttaaaag
    66901 aaaatccaaa ctataaaagc ttaaaacaat ttgaaaataa agataatcca aatgcacatt
    66961 ataaaacaac agcagttgaa attatgaatg atgtcaaaga tttagatata ttcgtatgtg
    67021 gagttggaac aggtggtact ttaataggaa ctgcaagata tttaaaagaa caaaatccaa
    67081 atataagagt aattgcactt gaaccaaaaa aatctccagc tatatcagaa aacaagactg
    67141 gacctcataa aatacaagga ataggtgcta actttgttcc tgaaaattat gattctagtg
    67201 tagttgatga agtaatatta gtagatgatg aagatgcatt tgatacagtt aaattacttg
    67261 cagcaaaaga ggggatttta gtagggatat cttctggagc aaatatattt ggtgctatag
    67321 agatggcaaa aaagtatcca gataaaaaga tagttacagt agctccagat ggagttgata
    67381 agtatatgtc tatgggaata ttttaataat tttatttgag ggagtgaata ctttgtttaa
    67441 gaaaataaat aaagatattg aatatataat gaagaatgat ccagcagcta ggtctaagat
    67501 agaagttttt ttactttatc catcagttca tgcaatgata atgcatagga tggctcatgc
    67561 tctttataag aagaagaagc tttttacagc aagattaata tctcagatat ccagatttat
    67621 gactggcata gaaatacatc ctggtgctaa aatgggggaa ggtatattga tagaccatgg
    67681 aatgggtgtt gtaattggag agacagcgga agtaggtaat agggtgacaa tatatcaagg
    67741 agctacttta ggagctacag gaaaagatac tggaaagaga catccaactg ttggtgatga
    67801 tgtattaatt ggtgctggaa caaaaatact aggaccttta aatataggtt caaattcaaa
    67861 aattggtgca aattctgttg tcgttaagga tgtacctaat ggtgcaacag ttgttggtat
    67921 accagcaaaa atagtaaaaa taagaaacct agaacctgta aaaaagaata aaaaagaagt
    67981 gtcctatgag tatgatgaat tagataatgt atattatata taggatttat ataactataa
    68041 aataaacttt ataaaaatta ttttaaaagg tatttttttc aaatttgagg acataataaa
    68101 aaagaactga atgttacagt tttggttcat caatctttga taaacaagat tttaaatttg
    68161 tagcgtctag gaggatttta ttatgaaagc aaatgttaat caagatactt gtataggttg
    68221 tggattatgt ccatcaatat gtccagaagt atttgatatg aaggatgatg ggaaatcaca
    68281 tgttatagtt gatgaagtac caagtgatgc tgaagaatca gcagcagaag ctagagaaag
    68341 ctgtccagtt gatgcaatag atgtgcatta atgaaataaa tgcctataaa aattgaattt
    68401 tcaattttta taggcatttg tcttttattc agttagtatt tcaacccctg tttctgtaac
    68461 taaaaccata cattcccatt gagcagataa tttaccatct tttgtataaa tagtccaatt
    68521 attttcttca tcaacaaaaa tttcgtgagt tccttcattt accataggtt ctattgtgaa
    68581 tatcatccca ggaaccaata gcatctcagt ccctttttta gatacataac ttacaaaagg
    68641 gtcttcatga aagcttaatc caactccatg accacctatt tctctaacaa cagagtatcc
    68701 atttttcttt gcataagagt tgatagcatc acctatatct cctaaaaatc cccatggttt
    68761 ggcaacttca agaccttttt ggacacattc ctttgtaact tgaactaatt tttttgcatt
    68821 ttcgttaaca ttgcctatca taaacattct tgaagcatct gaatagtatc cgttaaaaat
    68881 agtagaaaca tctacattta taatatctcc atcttttaag ataatgtctt tacttggaat
    68941 accatgacaa acttcattat ttactgatgt acatacactt ttaggaaatc cattatagtc
    69001 tagtggagca gggatagctc cattttgtag tgtaaagtca tgaaccaact tatttatatc
    69061 ttctgtagac attccaattt cgattttatc tgaaatataa tccaaaattt ttgtgtttat
    69121 tacagcactt ttttttattt cctcaatttg actttcattt tttataatat catgagttgg
    69181 tacaatatga cctaacttag caaatgaatc tattttatta tccatatcca tatgacattt
    69241 tttatatttt ttagtacttc cacaccaaca gctatcattt ctatttaact tcataacttt
    69301 tcatccttct tttattattt atttaaatta tgggttacat aaactatttt aaaacataac
    69361 cattataaat attataacat aaatactaag aaatccttta tagatagtga tttattcaaa
    69421 gtataaatta ttatatggtt attgttgatg aaaagaggat agttaaatgt attattggat
    69481 attagcgcac ttaatagttt agttcaagtt tttcaagaaa atcatatgtt agaggacaat
    69541 tttcctttaa agtatttttt gaatcttcat caagataata atgcacaaat gattctgcaa
    69601 aaaattcttc tataaacttg cttatatatg catgtgcaac ttgtttaggg tcataaagct
    69661 tatatctttc ctgagcaaat acttccataa attcttcaga atttgatttt ttatttaaaa
    69721 catttttatc tatagcatgt gcagtttcat gtaattctaa attttttgat gaatgtacat
    69781 ttgcatagct agggttacta taacctattt tagctactat agaattattt ctatatatac
    69841 caggtacatc tttccaagtc ttgcctgatc ttacccaaca tggaggtaat tgatatttta
    69901 aatcactaaa ttctggttca tcagttagat ttgaatttat taattttatt tttatatcct
    69961 tttctttaag tgtctgtaaa tatttaatat ttatttttgc aagtctgctc ttcatatttt
    70021 caacttcatc tttatcataa ttcaagtcat caggaagtat aagcatttgt tcaattatat
    70081 ctatgctact gtcttttata tcttcagatt cttcatcaaa tttatattga agagtattat
    70141 tttcatagat agttatattt gtattatttt ccatataata agagtgaata tcctctaagt
    70201 ctaaaatatt catttgttgt aaaatatgtt ttgtttcgcc actccatact actaaagaaa
    70261 gtgaattaaa attaattagt ggattttcct ttgcttttat atcattgctt atatctacat
    70321 caaatacata ttcaattgag tcttctatgt taagactatc tgtattcttt ttaatatata
    70381 aatatgcttg ttttaagtct atataaatct catctaaaga ttcatcataa aattctgata
    70441 aattattagt aaagagttct tcacttaaaa gttcattttt atcagttata ctttcaatta
    70501 aaatattaat ttcttttatc atatcgtaaa tacttatttt tctatttgct ttttcactag
    70561 atacattgca tggcgcaaga gcaatgcaat aaaaatcttt ttctttttta taaaaggctt
    70621 taagtgattt tgataaaagt gtaaagtcta cacctatctg taagttgacc ttaagtgagt
    70681 cattttgtaa taattcagta ttattttttt tagctatatt taaattgttt tccataatca
    70741 ttgccccctt tttattaggg tatcataatt tttttatatg tgtcaatttg tttttttgaa
    70801 aattataatt tttttgaaaa ttttattttt tataatttgt gaatttttta ttatagaaat
    70861 aaatatgtta ttattatgtc aaaatttagc attagattca tgtagagtat gttttataca
    70921 tatattataa ttaattcttt gaagattgca tattcaaaat acacaccatt tttttaattc
    70981 tataatataa tatttatata tttaatgtta ggatgtgatt taaggtgtat tttacatata
    71041 ttataagatg taaagatgat tctctataca ctggatatac cagtaatata gttagaagaa
    71101 tgaatgaaca taagttagga attaattcaa aatacacaag agcaaaggga tttgaaaaac
    71161 tagaagttta ttttgtgacc aacacaaaaa gcaatgctat gaagttagaa tactatataa
    71221 aaaaattaac tagaaataaa aaattgtcta taataaaaaa cccaagtata cttataaatt
    71281 taattgataa taaagaagat tatattattg gtaaggaaat agaacaatta acataaatat
    71341 ttatagtaac attataatgg gtgcatatag tgtaaaaact tgacaataaa tactattgta
    71401 atataatgaa gttataaata tagtaaatta aaatagctag gggagccaag agctgagagg
    71461 tataccgacc cttacacctg atctggataa taccagcgta ggaaagctta gtaaaaattc
    71521 aagtatgtat tatttgtgat atatgctatt tctaagctat acctattgta ggtatagctt
    71581 ttttaattaa gttatttaaa ttaaacttta ggaggcaaca atgagtaatt ataaaatacc
    71641 aacacttaca atagctggct ctgattcatc tggaggagct gggattcagg ctgatttgaa
    71701 aacgtttagt gcaattggta cttatggtat gagtgtaata acagctataa cagcacagaa
    71761 tactaaagga gtttttgctg tagaggattt aaataagaaa ataataaaaa aacaaataga
    71821 ggcagtcttt gaagatatac ctccaagagc tgtaaaaata ggaatggttt caagtcctga
    71881 gattatactt gaaatagttg agaatctaaa gaaatacaat ccaaaatatt tggttgtgga
    71941 cccagtaatg atatctaaaa gtggatatta tctattaaag ccagaggcaa aagaaaactt
    72001 aattaagtat ttgataccac ttgcatacat aattacacca aatataccag aggcagaaga
    72061 aataacagga ataaaaatac ataatgtaga tgatatgaag agagtaggag aagaaatact
    72121 acaacttgga cctaaatttg tacttatgaa aggaggtcat ttagatggag aagcagtgga
    72181 tattttagtt ggtaaaaata tatttaaagt ttataaaagt gaaagaattg ataaaaaaaa
    72241 tacacatgga acagggtgca cattatcttc tgcaataaca tcttatctag cattaggata
    72301 tgaaataaca gaagcagtaa atctaagtaa aatctatata acagaagcaa taaaaagaag
    72361 ttttgatata ggtcatggag taggaccagt acatcatttt tataaatttg agtaataaaa
    72421 aaatattgga ggtagaatat gtataattta attaaagatg taaaaaaatt aaatccattg
    72481 gtaattcatt atactaataa tgtaactata aatgattgtg ctaatgtgac tttagctgta
    72541 ggagcaagtc ctcttatgag tttttcatat gaggaagtag aagaaatggt aagtgtagca
    72601 aattctgtag taataaatat aggaactatg aactcaaata tgttggattt attcctatta
    72661 gctggaaaag cagcaaataa gtacaataaa cctgttgttt tggacccagt tggagtattt
    72721 gcaagcaaag cgagagcaga acttacaagt agacttttaa atgaagtcaa atttagtgtt
    72781 gttaaaggga atgtatcaga aataaagttt ataggtggct ttaatgtaag gggtaaaggt
    72841 gtagattcat ttgatgaaga agaagattct actgagataa taagaaagat tgctgaaaag
    72901 cttgaatgtg tagttgtagc aactggaaaa atagatataa taactaatgg taaaggtaca
    72961 tataaaataa acaatggaac tgataaatta aaaggaatta caggaactgg atgtatgact
    73021 gctagcttga ttgcaagttt tatggctgtt actgagaata tattagaagc agcaacaatg
    73081 ggtgttctta caatgtcttt aagtggggaa ttagctaatt taaataatcc accaataggt
    73141 acatttaaag aaaatcttat gaatgctatt tatcaaatgg atatagatac tttaagtaaa
    73201 aattccaata ttgaattttt aaattaataa agagtaaggg agacttaaaa tgattgataa
    73261 agaatcttta aaaaaatgtt taaagttgta tttagtaact gactctgaaa tgcttagagg
    73321 tagagacttt tataaatgtc ttgaagaggc aatatcttct ggaataacaa ctgtacaact
    73381 tagagaaaaa aatgcttctg gaagagagtt tttaagaaaa gctatgaaac ttagagaaat
    73441 aactaaaaga tatggtgtta agtttataat aaatgataga gtggatatag cacttatttg
    73501 tgatgcagat ggagtacatg taggacagag tgacattgat gttagagagg ttagaaagct
    73561 tataggaaac aataaaattc taggagtatc agcaagaact ttagaagaag ctatttgtgc
    73621 aaaaaatgat ggcgcagact atttaggtgt agggtctata ttcacaacat ctactaaatt
    73681 agatgcaaaa tcagcttcgt ttgaaactgt taaagaaatt aaagaaaaag tagacatgcc
    73741 atttgtacta attggaggta taaatttaga caatatagat aaacttaaat gtttagaaag
    73801 tgacgggtat gctataatat cagctatatt aaaagctgaa gatatctcta aagaagtgga
    73861 aaagtggaca ttaaaaatat aaaattggct ctggtagtga aaaaaatgga aaaatttgat
    73921 ataatctaag agtaaaattt aagcaattat aaatgataaa cttttctaca tatacttttt
    73981 aatcaagata tatgtagatt tggttaaaaa ggagctataa atgattagga tattgttagt
    74041 gtgtgttgga agcatgtctt ctaccctatt ggtaaataaa atggagaagg atgcaaaaaa
    74101 aagaaatata gactgtaaaa tatgggcagt tggagaagga gatataaaat cggagcttga
    74161 taactttgat attttacttc ttggaccaca acttagattt atgcttgatg acgtaaagtc
    74221 tatagttgga gatagagctc cagtatctat aatagatatg gtaaactatg gcacttgtaa
    74281 tggtcatgct gtgttaaatt cggttttaga aatattaaaa taaataataa aagtggattc
    74341 tatataatag agtccatttt tattatttgt tattaatagg cttaaaactt agcttaccat
    74401 ttcttttttt aatctccaca tagcaagtga aaaacttgaa cagcacaata ttaaaaatag
    74461 taggataaca ggcagtatat ctccaataag aatagtctca ccaaatatta agctacgtaa
    74521 agcgttaata acatgggtaa atggattgag catcactgct acttttaatc ctccagataa
    74581 actttctata gggaaaagag ctgaacttaa aaagaaaata ggaagtacaa ttgcagtcat
    74641 aattgtttca taaactattt catttggcaa taataaactt atagaataag ctagacttga
    74701 taaaaagaag gctgtcataa atatcagtac tatcataagt aggattccac caatgccaga
    74761 ttctatcctt actgagaaga atatacttac tatacacaaa ataattactt ctatgaagga
    74821 aactaagata gcttctaata attgaccaag gacgattgaa tacctactga taggtgcaat
    74881 taagactcta tagaaacttc cactgttctt cattataaag tttataatac caccactact
    74941 acaagaagaa aacacaacca gtacaatgat acctggtagt ataaaagcag tataattatt
    75001 gatatttata ttattcatag tttggtttgc aatagaacta taaagcacaa gccaaagaaa
    75061 aggttgtaat atagtgacta caaatgagat tggattttta aaacgccact tcatactacg
    75121 ccataagata tttaacattc ccattcctcc tttaagcttt ttttagaact tgtaaatgct
    75181 aaaaatacat cttcgagact tggctctaca atttctattg catcaaattc tatatcatgt
    75241 tctaaaagcc atttatttat taaagtaaaa gcagttctac tatcgtttac acttataaaa
    75301 attgaatttt ctcgtacgct cataaacttt actaaaccag tacttttaat tgaatcttta
    75361 tattttttta tatcttcagt attatggaaa gttatacgta gtatattttg tctaatgtaa
    75421 ctacgtaaac ttgatggtgt tccttgtgct aaatcctttc cattcttcat aatacaaata
    75481 ttatcactca attgttcagc ttcttcaaga taatgagtag ttagaaatat agttgtgcca
    75541 tactcatctc taatttttaa taacatatcc cacatagatt ttcttgaatc gacatccata
    75601 ccaacagttg gttcatctaa aaataggatt ttaggagatg ataccatatt catagctatg
    75661 tccaatctac gttttacacc ccctgaatat gatgaagtag gatattttaa gtaactagat
    75721 aagtcaaact tatcaattaa agagtctatt ctttgttttg caatctgtgg ttctacttta
    75781 tacattttac tttgaaatac catattttcc ataagggata aatgttcatc aatagagatt
    75841 tgctgtgcta cacaagcaat ttgagtacgt atccaagaag gattatctac taaatctttt
    75901 ccaaacattt ttacatttcc agatgtaggt ttgtaaaagg tagtcaaaat atttataaga
    75961 gaagatttac cagcaccatt aggaccaagt aaagaaaaaa tttctccagc atttacatta
    76021 aagcttagac catttaaagc tttcacacca tttttatatt cttttactaa attgtctatt
    76081 tcaatcgcta acatatatta ttcctcctct ttaagtggaa atattatctc tgtaatatag
    76141 ttatctgggt ttccttttat caacatacct ggtcctttaa taaatacttc tctccaagga
    76201 gtttgtattt ttatattatt ttcatgaata tatttaaata tcatttcata cgtttttggc
    76261 aaattactat aagagcctgt gtgagtaaaa aataaagctt ttgttttagg aaattctttt
    76321 gtagttatac ccatacgatt tggagtttca gcagttggaa cacataattc catttctgca
    76381 acaccagttt tttggtcaac atcatagtag caaaagaatg gtgcaccgtt agactttcct
    76441 tttatagctt taaatacatt tggaaaatac tttgttgcct cagtcatagg tccattataa
    76501 cgcatggtag ccactgtgac tgattcgata tttttgattt caattttgca attcatttgt
    76561 ttccctccta atgtgtgttc atattcttac tagattttta agcattaata catataagat
    76621 tttgattagt tgaaaacata taatcttatc tcgtttgctt gttttcaagt ctaacataac
    76681 ataaaatata tatcctctca tttgatgctc cattttgtaa agctattatt taagctttac
    76741 tttagatttt ttagcaaatt gaaataaagc aatttataaa ataagtattt acaaattaag
    76801 tgtattaatc gtataataca cttaatagga tactagataa agtctgaaat aaaggcgtat
    76861 ttttttaaag taagtgtact atcgtattaa tacactagaa taggaggaat catgaatttt
    76921 gaattagata atacaactcc catttatttg caaatagtaa agtatataaa gagacaaata
    76981 gtaacaggag agttgaaacc aggagagaca ataccatcaa gaagagaaat ggcacttaat
    77041 ctaaaagtaa acttaaatac agttcaaaga gcatataagg agatgggtga tatgaatata
    77101 ataaatactt ttaaaaatta tcaaagcagt gtaacagttg atgaaaatat attaaaaaat
    77161 ttaaaattag agcttataaa tgaatcacta tctgttttta tagaagatat gaaagcaata
    77221 aatgttagca aagaagaagt tttaaaaata atagaagata agtattagtt ttttaacaaa
    77281 tagaaaactt agtttagaaa gtttatttat aagcatattg gatgtggagg atagtaaata
    77341 tgatagaaat aaagaatgtc agcaaaacat ataaaaggat gcaagggctt aaaataagaa
    77401 agatagaagc tttaaaaaat gtaagtttta atatagaaaa gggaaaaata actgcattac
    77461 ttggtataaa tggtgttggt aaatcaacta tgttaaaagc aatagcagga cttataaaca
    77521 ttgatagtgg agaaattcgt atagatggag aaaaaataaa tgaaaaggta tacaataaat
    77581 tggcttttgt tccagatgta caatctcact ttagcaatac aacaataaaa gaaacatttg
    77641 aatttatgga aattttttat tcaaagtgga ataaagaaaa atcaaaagaa atgatggaca
    77701 tatttaaatt ggatgaagat gaaataattg ataacttgtc aaaaggaaac attgcaagag
    77761 taaaattaat acttggattt tgccaagacc cagagtacat acttcttgat gaaccattta
    77821 caggaattga tttgtttaag agggaagagt ttataggagt aatagcgcaa tatatggagg
    77881 aaaatcaagc cattatcata actactcatg agatagtaga gatagaaagt ttagttgatg
    77941 aggttgtaat tcttgatgaa gggcagatta taacttcatt taatgcagaa gaattaagag
    78001 aaagagaagg taaatctata ttagataaga tgagggaggt atataagaat gaataaactt
    78061 ctatatctaa taaatgtaga tttgagaaga agcaataagt tttatatagc ttatatatca
    78121 tttttttcat taattacact tagtttaaat ttattcgaaa ttaataaatt taaaaattct
    78181 aaatttatta tgaacttagc aatagaagat tttggaggta tattttatgg actagggata
    78241 cttagtaatc ttggttttat ccaaaatata ttgttctttg gaatgttggg actttttata
    78301 tactatattt ttatgtggaa aagagagttc ttttcaaata atcaaagtat ttatacactt
    78361 atgatgttac ctcaaaataa gtttaagatt tgtatatcta aatcaatagt tttgataaca
    78421 atgatatatg gttttttgat aagtcagaca gcaacattat ttatatgtaa atatatattt
    78481 aatttcattt ttagaaatat tcctataatc aatatgaact ttgccaaaga tttatattat
    78541 ttaaacttga agagtatacc aattgatttt atctctttta tggctattta tgtattttta
    78601 ctacttatag ctatttctat tgtaaattgc tgtatattat ttatcttttc ctatataaat
    78661 aaattttatg taattttaat cactttgctg attatagcag gcttatattt ttcaacaata
    78721 tatataaata taatcaattt atttagaaaa tattataatc ttataggatt tcaatttaac
    78781 aatttagtag cagggttatt aagtttttta attataatgt ttattctaaa tggaatatct
    78841 tatttgctaa ttaaaaagaa agtatctctt taaggagggg tggtatgaaa ttaaaatcta
    78901 aaatatctat acttattata tttttgactt tagcaatata ttttagtata ggtttattaa
    78961 ataatgaaga taatttaaag ataaaaacta taaaaggtga ctctaatgaa ttagaccata
    79021 taaacataaa ttttggatat gctttgaatg gatatataaa ttcatattat acaataaatg
    79081 gaagtaacaa aactaaaaag actgaattaa taaaactaca aaaggatagt aagaacacaa
    79141 ataatttaat tgatgtatct agtggttcag atttaattgc tcatgttgga tttgaaatga
    79201 atgaggagtc aaaagatata aactttgtga tagatgagaa aaaagaagat ttagaaaaag
    79261 gtgtatttcc atcagaaggt agtgataaag aaattgaata tgaaaaatta gatatgaata
    79321 attttacaag gacaagatat aaagtagata aaagtacaga tgattattat gcaaatatac
    79381 tagcatcaaa aagatataaa aaatacttat atgtatctgt actttatgct acaagtgatt
    79441 catcagaaaa taacaaagaa tattcaagta ctatagatat aataaaaatt aatccagaaa
    79501 ataaaaaaat caagactata aaaagtataa atttaagtaa ttatttttcc gagaaatacc
    79561 aagacataga gaacataggt gtaagttatg ctagcaaata tgaggataag atgtatattt
    79621 tagtaaatgt actaaataca aacataggtg ataatagtaa ttctaaattt catttacttg
    79681 agtataatct tgaagaaaat aaggaaagca taatggaatt aaaaactgat agcaaaatgg
    79741 ctttagcaaa agcaaagtta gaagctaata aattatatat ggtaatgtcg aatgattatg
    79801 ataatagttc aattacagag ttaaatttac ttacctataa tatattagat aaaagcttag
    79861 atgaagataa atatgtttta gataatagag aaaaaagagg aattagaagt attgaaattg
    79921 attcaaataa aatcgttgca tatacatcaa ggctaaactc tatattatct tgggataata
    79981 aatttatgct atatataata aataaaaatt ctaaggaaat tgtatatgaa ggagaattac
    80041 aatttaacag ttcaaatagt atgttagaat ttgaaataaa gtaggtgagt tgatgaaaga
    80101 tttaataaga ttattcgaat ttgaattaaa aagaaatata aagaattata tatttataat
    80161 aatttgttgt tgttcttttg taattttaaa catagtaaaa aatttaaatg actataatta
    80221 cataatagaa aatgcagtta aaagtgaaca gttaacaaaa atcggaaata cgatagaaac
    80281 ggtaaatgtt acaggtttct caagctttag aaatataatg ggttctacag aatcgtggtt
    80341 tatgtttggt ataattgcat gtatttgcta tgcttttttt atttggtata gagactttaa
    80401 tggtaggagt aaatctatat atacacttat aatgctacct aaaaatagaa tcaatattta
    80461 tatatctaaa ttattaaata tattatttct agtgtatagc tatacagtag tacttacaat
    80521 atctttgttt attgcaagta agttgttgcc tagacatatg cttggtaatg tcacaaacta
    80581 tggttttgta caagaaacaa tatatgagtt aaaaatgtta cttccatata gctttgaaat
    80641 actatttgta gagtatatat ttttattgat aggatttgta tctgtagtat ttacatcaat
    80701 tcttataaat aaatctattt ataaagtaag cactttaata agttttctat ttttagtttt
    80761 ggaaatttta gtgtttataa tttctataga atttattata ccttatgaat acagtgatgt
    80821 atttactgtt ctatattcaa gtataaacat atttgtatgt agtcttatat ctaataaact
    80881 tttgaagcaa aagattgact tttaggaggg atattatgaa agcaaaaaat ataggaaaat
    80941 atacaatatg ttttataata gtatgttttt taatgattac tatgacctta atattgagtt
    81001 attttaataa ggataaacta tctgtaaaaa ctttaaaagg caatgtaaaa gatataggga
    81061 gagtaagtgt agtatataca cctaatataa gcaaattttc ttatgaggag gtaattataa
    81121 gtaaaaatgg agtaagaaat aataaaaacc ccaaatcaag aattagaaat gattatttaa
    81181 atattgacaa aaaatacagt gattttgtta atgataaagg aaaagaactt atatataaag
    81241 atgatttgaa tataggagaa gcgtatacct ctgttaagtc tgatttagta caaggaatga
    81301 atgctttaaa tgattgtata aaggtttcaa ataaaaattt aaaaagtggg gtagaagaaa
    81361 attttgatat taatttaaat aagtctgatt ttaaagaaaa cagttggaaa accttgttta
    81421 ataaaatata taaaggcaat ttatatatgg taattagtga aactaatatt tcaggttcta
    81481 aggtcaataa tatttgtata ttaaagatag atataaaaaa taagtcttat aaattattaa
    81541 atagatttaa tttaggatta cagaatggat atcaacaaaa tatcaatgaa attaaatttt
    81601 ctattggaag taaattatac ttagaaatag taaataataa aagtaaaaat ggagatattg
    81661 aaggacatga tagttactct aaccttatta tatatgatat agaagataac acttttaata
    81721 taagtaataa atttatggat aatctaaaca aagaaaagaa tgcaaatcca aaggagattg
    81781 gcttattaag taaaactaag ctagattata tgataaaaaa taataaattg aatcttatag
    81841 ttacggatat gagtaattcc ataatcaatc ttgtttatga tattaattct aatgagatta
    81901 aattagaaga ttatgagata cttgatttaa aagtagatta taatgaagca tcatctggag
    81961 ttaggaaagc taagttactg gatgataaga tttattctat ttcaggtatg aagaacagta
    82021 tatcaggaga attaaaagga tttaaaggga ttgttgatgt agtcggaact aagccagtaa
    82081 aatttcaagt atttgatatg aaacttaaaa agaatattta tgaagctgag ctaataaatg
    82141 gagatataag tttacaagaa aagttatttt ttgttgcaaa ttaagtatta gaattaattt
    82201 tagaacttta aacttttata tgtatcacag ataagtataa gtaagggagt gtctcaaaat
    82261 aaacttttta gttcatgaga cacttttttt atatgaaatc aaatatattt tcattgttta
    82321 gatttatttt gataatgaaa aaaagattat ctttatttta agaaagacat ttatttataa
    82381 ttatatacaa aaatattttt taatgttttt gtgtataatt ataacaattt aatttatatt
    82441 aatgcactta aatttgaaat agaatgctta tagtggtaaa attaattatt agaatattag
    82501 aaataataaa taaataatac attgtactta aaagggggag aaatttaaga tgaacaaaaa
    82561 atatattaaa gcagggaatt taattgatgg aacaggaaat agtattatgc aaaataaggg
    82621 tataattatt gatggagata ctatagttga aattgaagat ataagagatg atttaaatgg
    82681 atatgatgtg tacgattact tagataaaac tgttatgcca ggcattatga attgtcatgt
    82741 tcacttgaca atggagccag ttggaaatcc aaagatatat tatgataatg tatcagatgt
    82801 agagcttgta gtaaatacga taaaacaact tgatgcttat ttggattcag gagtaacata
    82861 tattagaagc ttaggttgtc ccaaatatgt ggatgtacaa cttaaaaatc ttatagacaa
    82921 agggtctata gatggtcctg gtatagttac ttcaggtcca gttatatgta tgacaggagg
    82981 gcatggatat tattttggta ttgaaagtga tggagtggat gaatgtagaa aatcagccag
    83041 aacagtttta aaaaatggag tagattgtgt aaagataatg gcaactggag gtgtaacaac
    83101 tgatggagtt gagccagggt caccacaatt aactttggag gaaatgaagg ctgctgtaga
    83161 tgaagctata aaagcaggta aaataactgc cacacatgca caaggaagaa ctggtataaa
    83221 aaatgcagtt cttgcaggaa ttacttctat agaacatggt gtttatttag atgatgaaat
    83281 aattgatttg atgcttgaaa gaggaactta cttagttcca actgtggctg caccatattt
    83341 tattctaaat gcaggaaaag aaagtggaat aactgaagct actcttagaa agtgtgagat
    83401 tgttgccatt ccacataaag aatcattcct aaaagcatat aaaaaaggaa ttaaaattgc
    83461 agttggttct gatgcaggaa cttcttataa tgaacatgga aaaacatatt atgaaatgaa
    83521 gctaatgtca gattatggta tggataatat ggatataata gttgctgcta caaaaacagc
    83581 atctgaactt ttaagaattg ataaaaatta tggaactcta gaaaaaggaa agaaagcaga
    83641 tgttatagtt gtaaatggaa atccagtaga gaatatagac gtacttgcag atgtgttagc
    83701 agtatttaaa cttggtaaaa aagttagata aatagtataa aaataaaaaa gagtgtctaa
    83761 agaaattttt aaataattat agacactctt ttttattagt aataattaaa tcttttatac
    83821 tttagaaaat agattctatt ttatatttag atataactct ttaaaatcat tcttatgcaa
    83881 tataatctat agaatctaca catacaaagt atattcttga atcattagaa tttccaagta
    83941 ctataacatc atttttctta cctagaactt caacaccagt tagaaccaaa ctaccagcta
    84001 ctacagtaac ttgattattt atatttgaca tataaagatt atctaggata cctttattac
    84061 aacagcaatc atcacaatcg cagttacaat tacattcttt gtaatgtttt ttatcaagat
    84121 agtaacctaa agatgctatg aaatcttcat aatctgcagg tgtaatatca aatgcaacag
    84181 ctttaagatt acacaatgat gctaaatcta cgtttgctaa tggagtagat gcagcaagta
    84241 taaaatcaat tatagcagca agtattgcat ctaatatagc cccaaggtct atcgtaggag
    84301 gaataactgc atcaataagt gcaattaatt cagctactcc tggtatagtt cctatagtat
    84361 taattaatcc ctcaagagtt aaagggactg gaataggata agatactcta ccagctatat
    84421 ctattaaatc acagttacaa gcagaaaatc tttcaaaagt accatcaagt ccagataaat
    84481 tatcttttgg aggagctgaa agatctatac ctaccaaatt agcacctact ataaagaaat
    84541 ctgagataaa agcaaattga ttaaagttta caaaaggtct tagagcatca tatcttagaa
    84601 gttctaaggc ctctctcata ctttttttac aacaacattg ttttatttta ggttctttat
    84661 atttatttgg ataattatag tatctatcag ctacttgata attttcatag tatctttcat
    84721 ttgtatttgg ataatcttcc tcatattctt gtgtaaatct aaagtcctct ctacatttat
    84781 tattttccac taaatacact ccttttatat tttaatttaa atgtatagat aattaagctt
    84841 atctatatag taatattata tttataatgt aaaaaaatgt tacaaaagat attataaacg
    84901 aataaaaaat aataatttgt cagataaact tgtaaatttt tatgaataat ccattctaaa
    84961 acaaaaaact gtgtataaaa aaggtttata tgttatattt atataaatat aacatatgaa
    85021 cgagaaagga gtggtttgat aaatgattga ggtagataaa ttgtgtaagt cttttacaag
    85081 ggttgtaaaa gatgataaga ataaaagttc aataagaaag ctaaagaaag taaaaactaa
    85141 aaaagaagaa ttttttgctg taaataatgt ttcatttaaa gttatggaag gtgaaattgt
    85201 tggaatatta ggtccaaatg gtgcaggaaa gactacatta cttagaatgt taggtggcat
    85261 attaacacca acatcaggaa gtataaatat ttctggatat gattattcaa tagatagaaa
    85321 ttcagcaaaa aaagaaatag gttatctctc tggaaataca aaactatatg gaaggctttc
    85381 tccgagagaa cttctaacaa cttttgcaag tctatatgag atgtcaaaag aagatataga
    85441 agaatcaatt gaaaatattg taaaaataat ggatatgagt gaatttatag ataatagaat
    85501 tgaaaatcta tcaactggtc agactcaaag aacatctata gcccgttgtt taatacattc
    85561 tccaaaagta tatatttttg atgagccaac actaggtctg gatgttttaa gtagtgcatc
    85621 tattatagat tttatgaaga atgaaaaact aagaggaaaa actgttcttt actcaaccca
    85681 ttatatggaa gaagcagaaa ctttatgtga caagattttt atgattcaca atgggaaaat
    85741 aattgcatca ggaacaccac agagtttaaa agaggaatct ggagtaaata atttgagaga
    85801 tgtattcata aaacttgcca gaaaggagga catttaaatg agaagtaaga ttgtaaaata
    85861 catatttaaa aaagaaatgt tagacatatt gagagataaa aagactttat ttatgatgat
    85921 tgttgtgcca cttcttttat atcctttact tatgttatta atgattcaag taatgaatat
    85981 gtctgcaagt agtatgaata gtaaggacat taatatagct tttaataata aacctaataa
    86041 ggtgttagta tccatgattg aagatgataa tttagaaaaa gatactaaaa atacttcaaa
    86101 tgataaaggc aaaataagag tgttagatgt agataactat aaaaagtcat tagaagaaaa
    86161 taaaattgat gcttatataa agatggaaga aaaaaaatca tctataaatt atcaaatata
    86221 tataaattct tctcaagaaa attcttctaa tgcactaaaa agaattgaaa ctgttttgga
    86281 taaatataaa agatttacca tagaaaaaac tttatctgaa aaaggattag atgtacaagc
    86341 tactttagaa ccaataacat atagcactgt agatgttgca aagacggaag aagtggcagg
    86401 atacttttta ggtcagatac ttccatttat attaataata ggagttttac taggttcaat
    86461 atatccagca atagatgtta tggctggaga aaaggaaaga ggtacattag aaacattatt
    86521 tacactccca atatcaaact tagaactggt tatgggaaaa tatatggcag tttctcttag
    86581 tgcaatagta acagcaattt taaacatttt atctatggga ctgactatgg catttatttt
    86641 agttagtgga ggtattagta gccaatttgg ctttggaaac tttaattatg gagacttagt
    86701 cttaccaatt ataactactt taatttgcat atgtcttttt tcaatggtag tttcagcaat
    86761 aagtatgtgt gtatgttcat tagcaaaaag ttttaaagat gctcaaaact acataacacc
    86821 tcttatgtta attattatga taccatcata tgtttctatg ataccaaata tagtattgga
    86881 tagagtgaca gctgtaatac ctgtagtaaa tatatcttta cttataaaaa gtgtattatc
    86941 ttttaaaagc gatttaaatt taatagcctt agttttagca tcaaatgtag cctttgttat
    87001 attggcaatc atactactgt ctaagatgtt caattctgag gaaatacttt ttggtaatag
    87061 taagagtttt tctttcttag agaaaagaag taatataaaa aaagggtcta taccaactgt
    87121 aagtgatggt gttattttat atgcagtagg attagttcta ttgatttatg ttggttcttt
    87181 agttcaaatt aaatttggta tggcaggtat tataatgaca caattcatga taatttcttt
    87241 accattatta tttgcatgct atattaaagc tgattttaaa gaggtattta gcttgaaaat
    87301 tcctaaatta aaacacgtgt ttgggagcat tgttctttgg attggtggat acatacttat
    87361 tatgattata acacagctaa ttttattctt atttcctcaa aatatggaag ttgctgaaag
    87421 tttaaataag gctcttttta tcaaagatag tgttttactg aatttactag taatagcttt
    87481 attaccagct atatgtgaag aaatgttttt taggggattt atattttctt catttagtaa
    87541 atcaaaagat aaaaataagt ctatcaagct cgctataata tgcagtgggg tactatttgg
    87601 tattatgcat atggatttta ttagaataat tccaacatca atattaggta ttatatttgc
    87661 atacagtgtg tataaatctg gttcaatatt tgtatcaatg ttattgcatt ttttaaataa
    87721 tagtgtagca gttgtgttaa atcattatac aactggaaat ataaccaact tatataaatt
    87781 tgttgaagtt gatttttcga acttaaatgt acttaaattt gccttaattc ttctaataag
    87841 tcttatatta attatgttag gattaagagt tttagataga aagtctttaa gaaattaagt
    87901 ataaagttat tatatagatt aaaatattaa taagcactaa agtatatgga tatatcttgt
    87961 atataaaaat actttagtgc tattttatat attttaatta tatgaattat ttatcgtttc
    88021 atttatgtaa tgaaaatgtt atataaatga aacaataaat aatttttatt ttagaaattt
    88081 atatttaaat aatcaagttg aaagtgagat actaaaaaaa ttaatttagg aattatttga
    88141 tttattcatt tataaaaatt aattactgat ttgtcgaaac cattgtaata agaaaaaaat
    88201 gaaaaaataa agtgtgaata tgttgcaaat actgtatttt aataaaaagt agtcatttct
    88261 tgtaaaatgg atagtttata tctactttaa ttttgtaaaa ttttctgcta ctataattat
    88321 agaatgtagc atattcattg tcttaactat tgatttatat atttcatata ggtataatag
    88381 aaaataaatt ggattatttt ggcatataat tatttattaa aaggtgatta tttttgtttg
    88441 aattgtctga aaaattttat ttttatatta taattttaat attttctttt caaaactatc
    88501 cattttacaa gaaatggaaa cttttgagat gtacttattt gctaataaaa tagaggtgtt
    88561 ttaatgggag gaaattttta tgaggaattt acaaaaaaaa ttgatgtttt ttttatttat
    88621 ttgtataatt ttacaaatta catacacaac accagtctat tctttatgca aactctataa
    88681 aaacaactcc ataaataact ttgagtctat tgtgtctaat aatcagttta ttagcaaata
    88741 tgcaatacaa ataatactta ttatggctat aatatgtatg atgcttatat tctatataat
    88801 atatgacaaa ttaaatttta aaattaaatt gcaaaagata gcatatacag ataatcttac
    88861 aggagcaaat actatagata aatttgtaat tgatgctaac aaaatactat gtaaaaatac
    88921 tcaagtaaag tatgctttat tatatataga tattgataaa tttaaatata taaatgattt
    88981 atttggatat gaagttggga atgaaatttt gcgtaattta acaaaaatta ttaagagtaa
    89041 tatatttgaa gaggaaatgt ttgcaagaat atctgcggat aattttatta taattatgaa
    89101 atatatagaa gaagaagata taacaaagag gttaaaaact atatttgagg aattagactt
    89161 gtttaataat aatcaagaag aaaagtataa gttagtttta agttgtggaa tctattttat
    89221 acttccagaa gatagagata tcaactcaat catagatagg gctaatatac ctcataaaat
    89281 ggcaaaggga ggacataaaa gttcatatgc attttatgat aataagattc atgaccaaga
    89341 gataaaagaa aaagagatgg aaaatacaat gttttcaagt ctagaaaata aagagtttat
    89401 tatatactta caacctaaga tagaacttaa tacaggagag atacaaggtt cagaagcact
    89461 tgttaggtgg aaacgtcctg ataaagggct aatacctcca aatgaattta tcccattttt
    89521 tgaaagaaac ggttttgtta taaatttaga tttatatgtg cttgaagaag tatgtatata
    89581 ccttagaaaa tggattgatg caggaataaa tccagttacc gtttcagtta atgtttcaag
    89641 aatacattta tattgcaata attttataga aacatacaaa aatataattg ataaatacaa
    89701 tatacctgca aagtatatag aacttgaatt aacggagagt atcatatttg ataattttga
    89761 tattttaatt gatataatga ataatttaaa aaaaatagga tttttaatat ctatggatga
    89821 ttttggttca gggtactcat cattaaatat gttaaaagaa attcctatgg atatcttaaa
    89881 acttgaccaa aaatttatta tggaaactta taatagtaaa agaagcaaaa taattgttac
    89941 taaagtaata gaaatggcaa aagagttggg tatgaaagtc atatcagaag gagttgagac
    90001 agaagaacag tttgaacttt taaaggaagt aaaatgtgat atggcacaag gatatttgtt
    90061 tggaaagcca atgccaattg aagaatttga acatttaatt gtatccaact tggtaagagg
    90121 gtaattaatc tgtaatataa agaatttaat aaattgtgtt aaaaatggac tctaatgtag
    90181 tgttcatttt ttttgtaaaa ttttttatac ttttactaaa aagtaattga catatacttt
    90241 gtattattat attattgtat taacaactta atacaataat ataataagga ggcatgaaca
    90301 tggaatggga acttgataat aacaaaccta tatatataca attagtagaa catttaaagt
    90361 taaaaataat ttcaggggaa attaaaatag gatctaaatt agaaacagtg agagcactag
    90421 cagaagatgc ggaagttaat ccaaatacaa tgcaaaaggc tctaacagaa cttgaaagac
    90481 aaggtttagt ttatagtcag agaactaaag gaagatttgt aacagatgat aaggaaaaaa
    90541 taaaagctat gaaagaggaa atagctaatg tggagataaa tacattaaaa gtaaccttag
    90601 aaaagcttgg atatgataga gatgaaatgc taaaacttat tacagaaaat ctgaaaggag
    90661 aattataaaa tggataaaaa tataaacaat gtttctcaag atggaatagt tgaatttaaa
    90721 ggtgtaaaca agagttatgg aactaagaat gttttaaaaa atattgattt aaatatacca
    90781 aagggaaaaa tagtcgggct gttaggacct aatggaagtg gtaaaagtac aatgattaag
    90841 ctaatgaatg gattattaca gcctgataat ggtgaaatta tgataaatgg aatgaaacca
    90901 tccatagata ctaaaaaaat agtttcatat ttaccagaaa gaacttattt aaatgattgg
    90961 atgaaggtat cagatttact taagtttttc tatgattttt atagtgattt tgatgttaga
    91021 agagcaaatg agatgattaa aagcttagat attgatgtaa atgaaaagct aaagacaatg
    91081 tctaaaggaa ctaaagaaaa agttcaactt attttagtaa tgtcaagaaa tgcgagcata
    91141 tatatattgg atgaacctat aggtggtgtt gacccagctg caaggtcata tatacttaag
    91201 actatattaa aaaattattc tgaagatagt actttactga ttgctaccca cttaataagt
    91261 gaaatagaaa acatatgtga tgagataata ttcatatcaa aaggagaaat agtgttacaa
    91321 ggagacgttg aagcaataag agaagaaaaa ggaaaatcta tagatgcatt atttagggag
    91381 gaatttaaat gttaggtaaa ttattgaaat atgagttaaa agcaagtgga agaatattta
    91441 taccgttata tatagccata ttgatagtag ctgtatttaa tggaatattt atgaatacaa
    91501 atatacttca ggtacaggga ataggaatac tagtattaac aagtcttttt atggcattag
    91561 gagttttaac tattgtagtt acaattcaaa ggtttagaaa aaatcttttg ggggatgaag
    91621 gttatttaat gtttactctt cctgttagca ctagttcact tatattatct aaatgtataa
    91681 cagcacttat atacgctgta cttagtttta tagttgcagt attcactttt ggagttctta
    91741 tgctttttgg tacttctgga attttactac ctgaaatttt agatttgttt aacactagtt
    91801 ttaaatggat ttctgaaaac tttttagata ttttattatt attagtagta atgtttattt
    91861 catattcatc atttattttg ttattatata catcaatctc aatgggacaa ttgccaaaat
    91921 tcaataaaca tagaaacata gtggcatttg cttcttttat agctataaat atagtaatat
    91981 caattgttgg agatgcagtt ggaagcatct taccaaatga agatacaaat atggtatatc
    92041 atcttcatca gagtcctagt tttatgcttg caatacttgg tagtcttgta gttgcaatag
    92101 cgttattttt cgctacaaaa tttatattag ataaaaaatt aaatttagaa taaatgtttt
    92161 tatatggagc catcttttga gtaatgttaa aagatggctc ttattattta tgtagttaat
    92221 tcatgtatat aatatgaata gggttttatt tctagttaaa tatatacata tgttgtataa
    92281 tgatattgcg tgtaaaaatt tgtaagaata actatacact ttatataagt tatatcaaga
    92341 aaatttaaaa atatatggat ttgagggaga agatatgaaa agttatacaa aggctaagtg
    92401 gagtgtttgg ggtataatta cattttcatt tgttttagta ttatttttaa ggatgtcaac
    92461 tgctgttgtt tcagacaatt tagcaaatga gttaggtttt aattctatac aaatttcaaa
    92521 tatagcatcc ttttgcctat atgcatatgc atttatgcaa atacctgcag gaattttgat
    92581 tgataaatat ggagcaagaa aaattagcag tcttggaata ataatggcaa gtttagggtc
    92641 aattttattt ggtttgattc aaagtataga attagcatat atttctcgtg taattgtagg
    92701 ggcaggaaca tcagtaatat tactttgtat tttaaaaatt caagggagat ggtttaataa
    92761 gtcagaattt gcttctgcaa cagctaaatt ttcatttgta ggaaatttag gtggagttct
    92821 tgctactttt ccacttgtgt ttttgtctga acttgttggt tggagaaatt catttttatt
    92881 aatcggtata attggtgttg taattggatg ttttatatat attattgtta gagatacacc
    92941 aaaagagtat ggattcaatg tagatactga accctatgaa aagtcagaga aggttaatat
    93001 tgttgatggt attaagtctg ttataaagaa caaatcaaca tggtataatt caatgataat
    93061 gttctctttt gttggtctta caagtgcatt tataagcttg tggggagtaa gatacataat
    93121 ggacgtttat ggtgtgagta agagtttttc tgcgtttata gtatcatttt ttacatatgg
    93181 atttatattt ggttcaataa ttatggattt tgtatttgct aaaataaggt ctagcaaatt
    93241 taatataata aaatttggag caatgataga tttgtttata tggattgtaa ttgtagttgt
    93301 ataccaggta aaaccaccaa ttatagtttt accaatatca ttctttatta tgggatgtat
    93361 agttatgtca catctacagg tttttaatga tgccaagtat aaaaataaag aaatttattc
    93421 tggactggca actagtgtta ttaatacttt tgaatttata ggaagtggaa ttattaattt
    93481 gattatagct atctctttac aagtaaattc atataatata gttgatggat ataaaaaagg
    93541 ttttgtagta tttatagtac taagtattat aactatagta tcatctcata taggggtaaa
    93601 aaatgatgat tgtaaggcta tatagtgttt tattaatagt ttaatttagt attatatttt
    93661 gcatatatat aacaaatagt ttgcattttc ctaagatgta taattggaat ataaatcttg
    93721 tttactatgt acaaatggta ttgtattata ttaaatagaa aataagaact ttaaactata
    93781 atattggttc taaaatataa ggtaaggagt tttttatgga tacgacgaaa atagatgata
    93841 taagcaagtt agatttaaat aatttagaca ttaataagat ggatatggga ggtataatgg
    93901 aaagtctgct agaatgggct actacaagcg gagtaaaact tataataggt atacttatac
    93961 tttctattgg atttaaaata ataaaaaaat ttgtaaacca tgttatgtta gtacttagta
    94021 aaagagatat tgatttaact ttaagaaggt ttttgaagtc tcttcttttg agtgtactta
    94081 aagttgccgt tataatcatt gttctggaat attggggaat gagtttgtct agttttgctg
    94141 ctgtgatagc atcagcaggg gtagcaatag gtttggcttt acaaggtagt ctatcaaatt
    94201 ttgctggagg atttattata ctattgatta gaccttttaa agtaggagat tacgtagaag
    94261 cagcaggcca tggaggaacg gttgaacaaa taggactttt ttatacacaa ttggttactc
    94321 cagataataa acagatactt atacctaatg gttctgtatc aaatgatagt ctaataaact
    94381 attcagcaaa gaatactaga cgagttgatt tgacttttag tgtagggtat gaagatgata
    94441 tactacatgt tagaagagta cttaaagata ttgttaataa tcataaatta ataataaatg
    94501 agccagaacc atttatagga gtagtagaac atggagataa tgctgttaaa tttgcaacta
    94561 gagtttggtg caagacagaa gattattgga caatttatct tgatttacta gaagaggtta
    94621 aagttaggtt tgacgaagaa ggaattacga ttccatatcc taaaatggat ttaacagtaa
    94681 aagaattaaa caaaatttaa ttttttaata tagtgtttaa atttaagaat ataatataga
    94741 tatacttata aggtttgtaa aaaattaata agtactgtta ttttgtaagt aaaaatataa
    94801 aagaatggga gtgtctcaaa atgaactttt tagttcatga ggcactcttt ttgtacgaaa
    94861 taaaatatat ttttattatt tcaacaatga aaaagatgct tgtttctatt ttgagacagt
    94921 ataattttta tgtaacttta attttagtaa atataaagtt ttaaaattga taaaatagga
    94981 ggaattttta atataaaagg gtaaataaag ggtttagagg gcataatata gaataaatta
    95041 atatatttaa ggaggatttt tatgtgtaaa aaaacgtatt tattagtggt aagtatactt
    95101 atagcaggtt tattaactgc atgtagtggg agcccaacta aggattcagg acaagcacaa
    95161 gataatacaa aaaaggaggc aaatgcttca aataatgctt taaaagatga aaaaaataat
    95221 gaaaatttaa tggaacaaga ttttaaagtg ccatacacag atgcaataaa catatttaaa
    95281 gataaataca aggatgctga tatagtagat ttaagtcttg agagagattt aaataaattt
    95341 gtttatactg tggaaggtgt agatgataat aatgaatata agatgaaaat tgatgctaat
    95401 acaaaagatg tattagaaga taaaacagaa aagttagatt cagaagattt aaatggagtt
    95461 gctagaaaag aaaaattaga tttaaatgac ataattacac ctcaacaagc tatggaaatt
    95521 gcattaaaag aacaaaatgg aatggttaaa gaatggagtt tagacaaaga tttagatgtt
    95581 actttttata aaataagaat agataaagat aaaaatgaat atgacataaa agtagattct
    95641 aaaaagggaa ctgtattgaa ggtagaaaaa gaagattaga agatttaaac tatctttaaa
    95701 ataatttctt ttttgaataa attttgttta aaatataaca agcagggtat aaagagacta
    95761 aataactatt ttaggaggag tacggtatgt cattgaaatc actaaaaata aaagaaaatt
    95821 tatattgggt aggttcactt gaccctgatt taagagtatt tgacataatt atgtatacac
    95881 cttatggaac tacttataat tcatatgtat taaaaggaac agaaaaaaca gttttgtttg
    95941 agacagttaa agataagcat tttgacaatt atattgaaag attaaatgat ttaaatatag
    96001 attttgaaaa aatagactat attgttgtaa gtcatactga accagaccat gcaggaagcg
    96061 ttgaaaagct tttggattta gctaaaaatg caaaagtagt agcttcagaa acagcaatta
    96121 aatatcttaa ggaaatcgta aacaaagact ttgaatatgt tgcagttaca gatggagata
    96181 cattatcaat tggggacaaa actttagaat ttttctctgt acctatgctt cattggccag
    96241 atactatata cacatatata aaagaggata aaactcttgt aacatgtgat tcatttggta
    96301 gtcactatag taatgataag atagtaaata cacttgatga aaatgaagaa aaggattact
    96361 tggatgcttt aagatactat tatgattgta taatgggtcc atttaaacca tctatggtaa
    96421 ctgctataga aaagataaaa gatttagata tagatactgt atgtccaggt catggtccag
    96481 tattaactga aaatcctaga aaaattatag acctttatta taactggagt gtaaaggaac
    96541 aaataaagtt agaaaaagaa gttacaattt gttatgtttc tgcacatgga tatacaaaga
    96601 ttatggcaga agctataaaa gcatatattg aaaaaaatag caactataaa gtaaatttat
    96661 ttgatgtaat agagcataag caagaagata ttttggcaaa aatagcagta tcacaaggtg
    96721 tattatttgg aacaccaaca atattaggag atgcgttaaa gcctatatgg gatatattaa
    96781 tatcgttaaa cccagttctt catggtggaa aagttgcttc agtatttggt tcatatggat
    96841 ggagtggaga aggcatagaa aatgctatgg agagaataag tcagcttaga atgacagcag
    96901 taaaaccttt tgctgttaac tttaaaccat caaatgaaga gattgataaa ttacattctt
    96961 atacaggtaa attcctagat aagttaaatt ctacttttgg aagtaaaaag aaaactaaga
    97021 aatttaaatg tgtaatttgt aatgaagttt ttgaaggtga tagtgctcct agtgtatgcc
    97081 ctgtatgtgg agctaaggaa gaccaattta tagaagttga agaagatgaa gttactttta
    97141 gaaaagatac tgatgaatat ttcgtaatag taggaaatgg agcagctggt ttttatgcag
    97201 cagatgctat aagaaaaaga aataaaactt gtaagataac tatgatttct aatgaagatg
    97261 agttgactta ctatagacct gcactttctg atggtataaa tgaagaactt ggttcagatt
    97321 tctacatgga agataaagat tggtatgata aaaataatat agtagtaata ttaggaacga
    97381 atgtagataa attagatgag gtgaataaaa ctattatagt gaatgatgga gctattaaat
    97441 ttgataagct tgtaatagct acaggaagta gaaactttat accaccaatt aagggtcatg
    97501 atttagaaaa tgtgtttact cttagaaata taaaagattt atatagtgta aaagaagcac
    97561 tagaaaaatc taagaaagtt gtagtgattg gtggcggttt attgggactt gaagctgcat
    97621 gggaatttag actaaaagga ttagaagtag tagtagttga agccatggat agcatactat
    97681 caaaacaact tgataaagaa ggtagtaaaa tattagaaca atgtgtaaga gatacaggaa
    97741 tagatgtaag attgggtgta gcagttgatg gtattgaagg tgatggaaaa gctcaaaaag
    97801 ttgtatttaa agatggagat agtgtcgatt gtgatatggt agtattttca attggtgtaa
    97861 gagcaaacac tcaaatggtt caggatacat ctgtaaaaat tgacagaggt attgttgtag
    97921 ataagacatt acagacaaat gttaaagata tatatgcttg tggagatgtt gcacaagtgg
    97981 gaaatattgg tttagcaata tggccatctt cagtagaaat gggaaaaata gcaggggcaa
    98041 atgcaagtgg agataatttg acatttgaaa gtgaagtata tccagtttca ttagatgcaa
    98101 tgaatgtaaa agtatttagt attggtaata tacaaaattt tgataaagaa atttcatcaa
    98161 aagatgaagg tcaaagaata tataaaaaat tatttatgaa agatggttca ttagttggag
    98221 ctatacttat aaatgattta agctgtactg ttaaattgat aagattaata tctgaaaaag
    98281 gtgattttga tgatattatg aaggctgata tactataatt taaatacatt aaaataaaaa
    98341 ggagttgtct caaaattgat ttttttctaa tcaaatttta aattcaactc cttttttgaa
    98401 tttttatata aaataacatg gaaattttag taatgtctgt ggttacatac ataggtttaa
    98461 ttgtttttta tatggattgt ctctggtata ataaattgaa ttgtgtttga ctgatagata
    98521 tttttattga aagttaatac ctgttatgcg ataataagga cgtgttaggg gagtttttat
    98581 aataacaatt aatcttagtt tttgtgttcc aatagtagca tcaacacatt ctgatgtagt
    98641 agttcttttc ttataaaaat tagttacaaa tatgcttgta attatttgat atgtaaattt
    98701 accaatatta taaatgatga cctcgataat aaggagagtg aaaaataatc tatgaacgaa
    98761 aatattttga ttgtggatga tgaaaaagaa atagcagatt taattgaagt atatttaaaa
    98821 aatgaaggtt ttacagtata caagttttat acaggtaagg aagctctaga atgtattgaa
    98881 tctaaaaatt tggatatggc tattttagat attatgcttc ctgatattga tggatttcat
    98941 atttgccaga aaattcgaga aaaatactat tatcctatca ttatgttaac agctaaaatt
    99001 gaagatatag acaagataat gggtttaacc ataggtgctg atgattatat aacaaagcca
    99061 tttaaccctt tggaagttgt tgcaagagta aagacacaat taagaagata tatgcgatat
    99121 aataattctt atgaacaaca gtcgataatt gttaatgagt atgatattaa aggattgatt
    99181 atcaataaag aaacacataa atgtagttta tttgggaaag aagtagcatt aacaccgatt
    99241 gaattttcta ttctttggta tttatgtgaa catcaaggaa aagtggttcc ttctgaagaa
    99301 ttgtttgaag ctgtatgggg agaaaaatat cttgataata ataacacagt tatggctcat
    99361 atagggcgat tacgtgaaaa aattcatgaa ccttctaaaa acccgaaatt tataaaaact
    99421 gtatggggag taggttatac aattgaaaag taaaaatatt aaagtcaatc ctgactttgc
    99481 tcaagtgaga aataaaattt ttatgagaac agctttaatg gcatttatag ccattatttt
    99541 catatggatt ttatattctt ttatattgta tggtaagttt tctatctgga tagtatcatt
    99601 ctttgaaaat gcttttcgta tggaatataa agctgcattg aatttatatc agcagatttt
    99661 ccgtaatagc atggagctct tcatgatact agctatggtg attgtgtttt ttataatatt
    99721 ccgtgtttat ttaaattggt ttacaaaata ttttagtgaa ataaatcaag gtatggactc
    99781 tcttatcaaa gaagatgttg gagaagtggc tttatctcca gagttattgg caatagaaaa
    99841 gaaaataaac tcaattaaac atatacttga acaacgtaaa tttgagacac aaatggcaga
    99901 acaacgtaag aatgaactta ttgtttatct tgcacatgac ttaaaaacac cacttacatc
    99961 agttatagga tatctgacac tacttcgaga tgaaagtcag atttctgaag aactgcgaaa
   100021 aaaatattta tctatttcgt tggataaggc agagcgtctt gaagatttaa ttaatgaatt
   100081 ctttgaaatt acaaggttta atttatcaaa tatatcactt gaatacagta cagtaagctt
   100141 aactcgtatg cttgaacaac taacatatga gtttaaacct actttgatga gtaagaattt
   100201 aaaatataca ctgaatgtta caccaaatat gatgataagg tgtgatgtta ataaaatgca
   100261 acgtgtattt gataacttat tacgaaatgc tgtttattat agttttgaag atactactat
   100321 tgaaataaca gctgtacagg aggatgatta tataaagctt aaatttataa atcgtagcaa
   100381 tacgattcca gaggaaaaac ttgagcgtat ttttgaacaa ttttacaggt tggatatatc
   100441 tcgtaattca aacagtggta gagctggggt gggacttgct atagctaaag aaatagtgga
   100501 gcttcataac gggacaataa cagctcatag cgagaacaat ataattacct ttaaggttat
   100561 tattccgatt gtaggaaatt tgtaagaatt taagtataaa aaaataggaa attctttagg
   100621 ataaataaat aaagagcact cttgttattg atataattac tgtatcaaaa caagagtgct
   100681 tttattttga tacagtaatt atatcaatag aaaaatgtga aaatatatta tgtggaacag
   100741 atgcaattgt aagtgaaggt tgattggatt tgaaatagaa aaagtatttt aacatgtttc
   100801 tgtagattgt ataaaaataa ataaatcaac aaaggagaat caaagatgaa taataaaaaa
   100861 attgcagtta tatttggtgg aaactcaaca gaatatgatg tatcattaca atcagctttt
   100921 gcagtacttg agaatttgaa tacggaaaaa tatgatattc taccaattgg aattacaagg
   100981 gagggtaatt ggtatcatta tattggagat tataataata tccagaataa cacttggttt
   101041 gaaagggata ctgatataat tccagttatt gtttcgcaga accgtgtcaa aaatggtatt
   101101 attgaatttt taatttctga tgctgtttct cagaatcata ttccaaatag tgctattgaa
   101161 tcatgtgaaa ataatattaa atacactaaa cttgattttg tatttcctgt attgcatgga
   101221 aaaaatggag aagatggaac agtgcagggg ttatttgaat tggcaggtat acaggttatt
   101281 ggatgtggta ctctttcttc agcattatgt atggacaaag acaaatcaca taaacttgtt
   101341 cattcagaag gtattaaaat accaaaatca atattactaa aatactcaga taaatttaat
   101401 gtggctgaac tgtcaaaaga cttaacttat ccattattta taaaacctgt gcgtgcaggt
   101461 tcatcatttg gtattagtaa aatttataaa aaagaagagt tacaagtagc agtagacttg
   101521 gcttttgaac atgataatga agtaataatt gaggaaaata ttgatggttt tgaggtaggg
   101581 tgtgcagttt taggaaacga tgacttactt gttggaagag tagatgaaat agaattgtca
   101641 aaaggatttt ttgattatac agaaaaatat acattgaaaa gttcaaaaat tcatatgcca
   101701 gctagaattg atttggattg tgagaaaaga atacaagaga cagcaaaaat tatttataga
   101761 actcttggat gttctggatt tgctagagta gatatgtttt taactccatc tggtgaaatt
   101821 atttttaatg aagttaatac aattcctggc tttacttctc atagtcgtta tccgaatatg
   101881 atgaaaggta ttggattgtc ttttgaagaa atattggaca agataattga ggtgtatata
   101941 aaatgatgaa taatatttta ttagataaaa ataaagaaga taaaatgaca aatactatct
   102001 tattgactaa agataaagtt tatgatggga atctaattct agtaaatgct tttttaccag
   102061 ttaaaacatc tgaagatata gatttaattc ctgtagatac aaggtttcca agtattctta
   102121 tgaaacgtga agctacaaat attttgcaaa atattttaaa aagtatatgt ggaataaatg
   102181 aaatagtacc tgtaagtgga tatcgtactg cagaggaaca acaagatata tattcaagtt
   102241 ctctgcgtga caatggaaaa gactttacta aaaagtttgt agcacttcca aatcacagtg
   102301 aacatcagac agggcttgct attgatttag ggttgaagaa agaggttata gattttatct
   102361 gccctgaatt tccttataat ggtatttgta atgagttccg taaggcagca ctacattatg
   102421 gttttataga gcgttatcag tgtaaaaaag aagaaataac aggaatatct caagaaccat
   102481 ggcattttcg ttatgtcgga tatccacatt ctgagattat caataaaatg aatctcgccc
   102541 ttgaagaata tatagaatat attaagagat tttcgtatac aaattgttta aaaatagagg
   102601 ataaagaaaa aattatagaa atcttttatg tgcctattca tactaaagaa gaagtgagaa
   102661 tctttatacc tgaacaatgt gtctatcaaa tatcgggtaa caataaggat ggttttattg
   102721 tgacattttg gagaaataga aaggactaag aaatggagga acaagaatga ttaggaataa
   102781 atcttatgca gggcttgatt attttaggat tatagctgca ttacttataa ttgcaattca
   102841 tacatctcca ttattatcat ataataaaat ggctgacttt gtgttaacta gtataattgc
   102901 tcgtattgct gtgccattct tttttatgct atcaggcttt tttctaattt caaaatataa
   102961 ttataattgt aataaactga aatcttttct aaaaaatgta ttatttattt acgggatagc
   103021 tattgtaatt tatattccct taaatattta cactggatat ttttccatga ataatttagt
   103081 gcccaatatt attaaggaca ttgtatttga tgggacttta tatcatttat ggtatcttcc
   103141 tgcatcaatt attggtgcaa gtattgcata ctttcttgta aaaaaactag gtttaaagta
   103201 ctcactagta atcactattg ttatttatgt aattggtatg tttggtgata gttattatgg
   103261 ttttttagaa aaaataccat tattaaagaa tttatatggg tatgtttttg aagtatcaga
   103321 ttatacacga aatggtatat tttttgcacc tgtatttttc atacttggtg gaataatatc
   103381 taataaatct aattatatgt caactaaaaa tagcttgatt ggatttctta tatcattctt
   103441 acttatgtta tgtgagggaa tgtttttaca taaactaggg gtacagcgtc atgatagcat
   103501 gtatattatg ttattgccat gtatgtattt tttatttaca gctttaacat ttttgaaagg
   103561 tcctcgagct aggttattac gaacatcatc attaattatt tatattatac atcctatgat
   103621 gattgttgtt attcgtatgt tttctaaaat attcggaata caaactgtct tggttgacaa
   103681 tagccttatt cattatatag tggtaagtat agcatctttt atagcttcta taattattat
   103741 attgattctt aaacctctaa aaaaagactt gaaaggagaa cagaaggtaa ataccaatag
   103801 agcttggatt gaaattgatt taaataattt ggaacataat gtaaagatga tacaaaaagc
   103861 tatgccagaa gattgtaaat tgatggcagt tgtaaaagct aatgcctatg gtcatagtgc
   103921 ttttgaagta gcgacttgtg caaaccaaat aggtgtaaaa gcatttgcag tagcaacaat
   103981 agatgagggg attgatttac gtcgatatgg aatactagga gaaatattga ttcttggata
   104041 tactaaccca ataagggcaa aggaacttca taaatacaat cttacacaga gtgttattga
   104101 ccttaatcat gctatctctt taaacaaaca gaaatacaac ataaaatcac acattaaaat
   104161 tgatacaggt atgcacagac tgggttttga tgttaatgat gtgaggtcaa ttttaaaggc
   104221 atttaaatta aaatacttag atatatgtgg catatttaca cacttgtgtg tttcagatag
   104281 tctgaaagat gaagatgtag actttacaaa taaacaaatt gaatgttttt ataagttaat
   104341 tgattttctg ttaaaaaaag gtataaaaat tcctaaagta catattcaaa gtagttatgg
   104401 tttttttaat tatcccaatc ttaagtgtaa ttatgtaaga attggaattg cattatacgg
   104461 gatattaagt tctccaaatg atacgactaa attgcaactt gatttacgac ctgttttatc
   104521 cttaaaatca caagtaattc ttattagaaa aatacaaaaa gatgatagtt ttggatatgg
   104581 aagagtcttt attgcaagca gagatagcgt aattgctata ttatctattg gttatgccga
   104641 tggtatacct agaaatttat cctgtggaaa aagttacgta ataataaacg gttgtagagc
   104701 agcaatagtg ggtcgaattt gcatggacca acttgctgtt gatattacag atatacctaa
   104761 tgtagaagtt ggtaatacgg caataataat aggaagagat aatttatctg aattatctgc
   104821 ttctgaagtt gcaaataact catgtagtat atcgaatgaa ttattgagca gagtaggaag
   104881 aaggttaaat gttataaaga agtaactcaa ttaaatagta atatttgttg tactgtgtaa
   104941 tttattttac tctgactaga catttttagt aatattatgt ctaatatata ttttttataa
   105001 cttatatgac aatttaagtt ataaaaaggt gatgtttcag atttttattt tgaaacatca
   105061 ccttttttgt tataatatat aataaaataa ttatacctta actgtaaatt tatatagagt
   105121 atttactttt tattataaga ttcatttttt gagattggta tataataaac atatagagta
   105181 tataataata gttaaagtta aaaaagggga aaagcaatat gcagtatata caagaattac
   105241 ttgatttgac tcaaaattat tgggtgttag ccacaataat cggcttatta agtgcattta
   105301 tagaaagctt tataccagcc ttaccacttg ttgctatagt tacagcaaat gctgcaatac
   105361 aaggattatt tattggatgt ttgttatcat ggattggctc aggacttggg acaacttcat
   105421 tattcttatt aataagcaga tttaatgata gtaagctttt taataagttg agaaatagta
   105481 aaactgaaaa agcaataagt tggatggata aacagggatt taagttacta tttatagcgt
   105541 atgcctgtcc atttatgcct ggttgtttag ttactatcgc atcagctttt ggtaaaaaag
   105601 atttaaaaga ttttgtgcca gcaatgttgg caggaaaatt tgtaatgttt atagttataa
   105661 gttacgtggc aagtgatata gaaggtttta taacaagtcc tttaaagata gcatcattta
   105721 tattattggt gtttttgtca tggaagattg gaaatagagt aaataaaaat cttgaaaatc
   105781 ataattatga tttccatcat aaaaaacatc acaatgataa agatgataaa atgatttagc
   105841 ttgtactaaa taaaacgtat cttaaaatga tttagtacta aattatttta agatacgttt
   105901 tattttttgt attaaggtac aaaattttta gttattttgt aaactaaaat atataaaact
   105961 tatttatact tagttcaaaa tattgttatt tattttttct acaactataa taaaatataa
   106021 aattgatatc caatcaaaaa aataactatg aaatttaata gcttagatat gaatttttct
   106081 gtttttgagt tagtttttat aggtagtaaa gaaatgttta tggtaatggg ataaaacaat
   106141 tcaatacctt ctttagtaat aaggtcaaga cacaagtgag atagatatcc tattataaac
   106201 ccactggata aacatgagaa aactatatta ttgttagtga agattgtcag agatttaaaa
   106261 aaactataaa taagtaataa ggcaattaga ctgtgagtaa accctctatg tctaaaccta
   106321 cttccaaata atttgtatat taacataaat tttttactta tgtaagaacc tctcatatct
   106381 atatctggaa ataaagaacc taaatatgca aaataaatat aaattataat taatactatt
   106441 ttatatgcaa tatcgtattt aactaggtac agattgttta taaaggggag tatcaaaagt
   106501 gcgaatatat aacctcccct ttcatgtgtt tcttttatca tataaaaatc ctcctgaatc
   106561 gtcactataa acattatatt ggtaaattta gactatcttt tattatatta tatagcaaac
   106621 ataagttttt ttcaaaagga ttttaatatt taattaatct tgagatttta aatttttgta
   106681 attttctaaa gcaccattcc aatttactac attaaaccag ttgccaatgt attcatttct
   106741 tctattttga tattttaaat agtaagcatg ctcccaaaca tcaagtccta ttataggagt
   106801 taggttttta cttacagggc tatcctgatt tggagtagtc ataatagata atttcccatc
   106861 tttagtagct acaagccaag cccaaccaga accaaagaca tctaaagcag atttttggaa
   106921 ctcttgctta aatttttcaa aagaaccaaa gtctctatca atagcttctt ttaaagattc
   106981 agaaggtatg gttttttctg gcgtcattat atcaaaaaag aatttatgat tataagctcc
   107041 acctgcatta tttcttacag ttgtagcaat atctttaggt aaagaatcta aattttgcaa
   107101 taattcacat aaagaataat tataaagctc aggatatttt tcaagagcag catttaattt
   107161 atcaacataa gcttgataat gcttatcatg atgcagtttc attgtttctt tatctatata
   107221 aggttcaagt gcatcatatg cataaggtaa tggtttaacc ttaaatttgt tattttcagg
   107281 tgtaaaagca aatgaagtta tgcactgtga gattataaat aaagacataa taactggtat
   107341 taatattttt ttcttcataa aaatcacctc ctaatatagt atttctagaa ataaaaaaat
   107401 atgaaatatt aacagataat ttataagaat ttaatagcaa tttcatttta aattgaataa
   107461 gttttaaagc caaagacaaa actatgaaat atagaataag actaaatgac agaaaggaat
   107521 tttgattata tggacggcaa tatttcaatt tattataaag gtgatatatc taaaaaagaa
   107581 aatattaaat ttaaaataaa agaatctgta aataatacaa gactttctag tagaatagag
   107641 tataaggatg aggaaaaaac ttttgatttt gaaagattta atgtaattga tgctatttat
   107701 ggaaataaac catttgaaaa agatggaaaa gttattgttt ttaatggaaa tatatataac
   107761 tatcatgaaa taaaagaaga attaattaaa aagggacaca attttactac aaatgatgat
   107821 attgaagtct tattggcatc ttatatagaa tttggtaaga attgtgtaca taagattaaa
   107881 ggaatgttca actttataat ctatgataga gaaaatgaaa gtatatttgg agcaagagat
   107941 ttatttggga taaaaccact ttattatata aataaggaaa atgcaataat tttttcctca
   108001 gagtataagt ttttacttga atatatgaaa aatttaaata taaatgaaag aagcttacaa
   108061 agttattttt catttcaata tgtacttcct gaagatacta tgatacaagg aataaggctg
   108121 ataccagcag gtcactattt tagggtagaa aatggtatac tatctttaaa gagatataat
   108181 aaacttgagt ttagaagtag tacaaaattt ttttatacta aaaatcactt aggcaataga
   108241 gatgtgaatg aggatgatat aagaaatata gtagtagatt caatagtaac tcatatggaa
   108301 gaggagaaag aaattggaac atttctgtct ggtggaatag attcatctat tataactact
   108361 gtggcttcac aaattaatcc aaatataaaa tctttttctg caggctttag tgtcaaagga
   108421 tatagtgaat tagaagtagc aaagaaaaca gctgataagt taggtataga aaatatccag
   108481 attaatataa cacaagatga atatataaaa tcattaccgg atgtaattta ttctttggat
   108541 gaccctatag cagacccttc agaagtaggt ctttatttct taattaaaga ggcaggtaaa
   108601 catgttaaag tagcattgtc tggagaagga gcagatgaat tatttggagg atataatata
   108661 tataaagagt atagtactat gaaatcagtt gtcaattcac ctacttatat taaaagtata
   108721 ttaggaagag tttcagaact tatgccaaac ataaaaggaa gaaattatct ttatagagct
   108781 acaacaccat tagaaaaaag atatatagga aatgcaaaag tttttgaaaa cagcgaagta
   108841 aaaagattct tttttaagta taaggaaaag aatatatatg aatacctgtt gtctaatttg
   108901 tatagagatg cacaaaaaaa taattacgat tatataagta aaatgcaaca tatagatgtg
   108961 aatacatggc ttcaaggcga tatacttcaa aaaattagca aactttctac agctgagcag
   109021 gttgaactta gagtaccatt tttatataaa gatgtatttg atgtagcaaa aaatttaaga
   109081 atggagcaaa aaataaataa gaataataca aaagttttac ttagagaggc gtttagagaa
   109141 atagtcccag aacatgttgt tcaaaggaaa aaattaggat ttccaactcc aataagagtt
   109201 tggttaaaag attctctagg ggatattgta aaggaaacta tttataattc aaatgtagat
   109261 gaatttatag ataaaaaata tgcaataaaa cttttagata tgcatcttaa aggtcataga
   109321 gataattcga gaaaaatatg gactatattt acattttgtc tatggcatca attatttatt
   109381 gagcataaaa atgtcgagta ttaatactgt tttcaatatt aatcagaggg caaaagcatg
   109441 caatgttttc accctcttga ttattatgga ataggataag tagaattttg attgattagt
   109501 ttactatctc aataaaatta ttggcaaata ttttgacaag attactttca acagctaaat
   109561 ttaagttttg tccatcatca tatccagcgg aaatcaatcc tagtaagttt ccaaacatat
   109621 ctaaaagagc tcctcctgaa ctaccactag agattggagc tgtaaattgt atcatttgaa
   109681 ccgtttcaaa atcacgaaaa gctgagataa ttccatctga aactgtatta aaaagaccta
   109741 aagggcttcc aattgcaact attttttgac ctctcacagg ttttttactg actttaacag
   109801 gtattggctt gcattttcta tcaaccttta tcacagctaa atcataatct gaatggtatt
   109861 ttataatttg gtaagatgta taaactttat catcattttc aaatctaact aaaaatgaat
   109921 acccatcatt gactacatga agattcgtaa gtatataacc ttcattattt attactactc
   109981 cagaaccact cttaaacggt ttattttcgt tattgcacac aacaatcata acaacagaag
   110041 ctgataactt tgcaaggtct tcataagaaa gttctacttc ctcatcttgt gcaatttttt
   110101 tagatgttag atttgtgtta ttaagtgtat ttttagagtt aggtttattc gtagtaggag
   110161 aagtcttatt ggtattttca ctgtaattta tatttgtaat atgcctttca aaaggtgttt
   110221 ctaatatatt tggagttttc ctagaaagtt caaatagagt agaaaatttt gaacattcag
   110281 gatataaatc aagaatatct ttatttggat ttatatataa aatatcacac ccaagttgtg
   110341 ataaaaaata taagaaaaaa agttcttgcc ttttaatatt tccaaagtat actatctttg
   110401 gtgaaatagt agtcttcacc ttgttataaa ataatttagg tagaaaatag tccatccaac
   110461 acaaaagttt aactgcaaag tttttgatga tagaggatgt acaatttggc atacttgtgg
   110521 aaaataaatc taaagtattt ttaaatgcaa tctttttagt ccaatttaaa gtgtcatttt
   110581 ctattttaca tggaaagtcg atattatata aatcccaact gttaaactta gaactatcat
   110641 aaatattaaa aattttaagc atcttatctg tttgttcttt gtcaaaattt atttttagat
   110701 tgtttaatct aatataggga attgtaggat tattaaaaaa ataagtatct atatttttaa
   110761 ttttttctat gtatttatca attgaatcat caacacctat atatcttgta aagtagactt
   110821 ctttaatata tgaagaactc ttatttttat aggtagtatc agatataaat tcaattagag
   110881 gttcagttga cttttttatt gaaatcttta atggtttaat agtacaaatc atattttttc
   110941 tcctataata agatgatata atctattata aaacaactta aaacaatata gtacaataat
   111001 tttgtagttt caaaataaaa tatgtacttg tttatataaa tgatatataa ttacatatta
   111061 aacatagctt ttatacattt aataaagtat gtaaaatcta tgtaaaaagt aagaaatata
   111121 aacatttttt taattatatt ttaaaaatat caagcaagtt ttcttcacaa atgaataaaa
   111181 aatgttataa tatgattaaa gaaaaagata aataattagc aagatttgtt tagctaaaat
   111241 taacaaggga gcgataaatt atgggtataa cattatcaaa aggccaaaag gttgatttaa
   111301 ctaaaggaaa tccaggtctt aaaaatattt tagtaggttt aggatgggat actaacaagt
   111361 atgatggtgg atttgacttt gatttagata cagcagcatt tttaacagga gcaagtggaa
   111421 gtgttactaa tgatggagat tttgtatttt acaacaattt aaaacataca tctggagcag
   111481 ttgagcatct aggagataac agaactggcg aaggtgatgg agatgatgaa caaatagttg
   111541 ttgatttatc taagattcct ggagaaataa gcaagatttc ttttactgtt acaattcatg
   111601 atgcgacaga aagaagacaa aattttggac aagtaagtaa ttcttatata agaatagtag
   111661 ataaagacac aaatgaagag ttaataaagt atgaattagg agaagatttt agtatagaaa
   111721 cagctatagt agtagctgaa atatataagc acaatggaga atggaagttt aatgcactag
   111781 gttctggctt tgaaggtggt cttgctgcat tatgtggaaa ctttggaata aacttataat
   111841 ttcaactata ataataaact aaagggggat attttccatg gctatagtat taaaaaaagg
   111901 acaaaaaatc gatttaacta agggaaatcc aggtcttaaa aatataaaac ttggactagg
   111961 atgggataca aattcatttg atagtggcta tgattatgat ttagatgtaa gtgttttcat
   112021 ggttggagaa tcacaaagag ttgaaaaaga tgaagatttt atattctaca ataacttaaa
   112081 acatccatct ggagcagttg aacacttagg tgataataga actggtgaag gtgatggaga
   112141 tgatgaggaa atattagtga atttagaggc aataccaaag catatacaaa agatagctgt
   112201 aacagttaca atatatgagg ctgctgaaag aagacaaaat tttggacaag taagcaactc
   112261 atatataaga gtattaaatt ctgaaaatga tgaagaaata ttaagatatg acttaggtga
   112321 agaatttagt atagaaactg caattacagt atgtgagata tataagtata atggagaatg
   112381 gaagtttagt gcagttggag caggatttga aggtggctta gaagcacttt gtagaaacta
   112441 tggcttaaat gtttaattta agcaatataa tatattaaat ataaataacc tatacaaata
   112501 atgtataggt tatattatat aaaattttgt ggaggtttag tatgtcgatt aatttatcaa
   112561 aaggtgataa aatagattta aaaaaatcta acccaggact gagtaacata cttgtaggtc
   112621 taggatggga ccctgtgcaa caatctggcg gaggtttttt taaatcgtta tttggtggag
   112681 gacaagctga tatagattgt gatgcatctg tatttatgct taatcaagaa ggtaaattaa
   112741 gtggaataaa agatttaatt tattttggaa atctaaaaag tgcctgtaaa tcagttttgc
   112801 atacaggaga caatctaact ggtgagggta caggtgatga tgaacaaatc ctagttaatt
   112861 tggataaagt tccatcaaat attcataaat tattgtttgt agtaaatata tacaattgtg
   112921 tagatagaaa acaacacttt ggaatgatag aaaatgccta tataagagtt gaagaccaag
   112981 gtaataagaa agagatagca aaatacaatc tatctgataa ttattctgaa aaaactactc
   113041 ttatagtagg agctatatat agaaaagatg gaagttggca atttaaagca attggtgaag
   113101 gaacaaaaga tgcgggtctt aaagaagtaa tgcaaaattt agacaggatt gagtgtgcat
   113161 atggaattta ataatgatat caaatattat aatgtagata aagaagaagt tacaaaagac
   113221 ttatctgtta atcctgaaaa aggtttatca gaatcagaag tcaagactag aagagaaaaa
   113281 tatggtttga atgaatttac tccaaaagaa gagggtagtt tttgggatga tttaaaagaa
   113341 agtttaagtg aaccaatgat agttatcttg attattgcag cagtagtaag tgcagtaatt
   113401 ggggaaactc atgatgcaat agggattgta ggtgctatag caataggtat agcaataggt
   113461 atgattacag aaggtcgttc taagaaagca gcagaggctc tttctaagtt gactgaaaac
   113521 atagaagtaa aagtattgag agatggggaa gtacatcaaa tttctaagag tgaattggta
   113581 ccaggtgata tagtatatat tgaaactggt gacatggtac ctgctgatgg tagacttata
   113641 gaaagtataa accttaaaat tagagaagat atgttaacag gagaatctga tgacgtatct
   113701 aaaaagtgtg atgtagtagt ttctatggaa gagatagaat ctaaaggagc agtagtagta
   113761 caggagccaa tacctgcaaa acagataaat atggtgtttg gtggtacact tgtagcttat
   113821 ggtagaggag ctctagttgt aacttcaatt ggagataata gtgaaatggg taaaattgct
   113881 caaaacttat cagaaacaga tgagcaaact ccacttcaga taaaacttgg aaatttaggt
   113941 ggtttgatag ccaaagtttc tagtgcagta gcaggattac tatttatatt tatggttttc
   114001 caaatgataa gtaagaatgt attaaatgta gatatgtctg gaatattacc gtttttagaa
   114061 tcaatagacc cagttaaaac agcatttaca gtatgtgttg cgttgatagt tgcagcagtg
   114121 ccagaaggtc ttccaactat gataaatatg acacttgcaa taacaatgca aaaaatggct
   114181 aaaataaatg cattggttac caaaaaagaa gcttgtgaaa cgataggttc tgtttctgta
   114241 atatgttcag ataaaactgg tacattaact gaaaatagaa tgactgtaga agttgcatat
   114301 gttgatggca gatatattga aagttcagaa gaggaaataa atagttattt tgaagaaaac
   114361 tgtatgataa actctacagc tgatgtagag cacaatgatg gtgatattaa gtatttagga
   114421 agtgctactg aatgtgcatt gcttttatat tacaaaaacg tagattatag acaagttaga
   114481 aaaaattcta atatagtagc tcaaaatcct tttacttcag attcaaagag aatgacttct
   114541 gttataggtc aagataatca tcatgtacta ttatcaaaag gagcaccaga agtcttactt
   114601 gaattatgtt cacatattca aagaggaaaa gacatagttc cattaactga aaatataaaa
   114661 catgagattt tagaagaaat aaagaaattg caaataaaat caatgagaac tttagggttt
   114721 gcatataaag aaatctcaca agctgaagaa gaagcagcag taactgctga aagtgatgct
   114781 atgaatgtaa gtgcaatgga aaataattta gtatttagtg gttttgttgg tataagagac
   114841 ccacttagaa aagatgttat agagtctgta aatacagcaa ataaagctgg tgtttctgta
   114901 aaaatgctta caggagataa tataaatacg gcaagagcta taggtgaaga gttaggccta
   114961 ttaaaaaata atatgagagt ggttgaagct tcatatatag atactttaga tgatgaagaa
   115021 ttaaaacaag agatacaaag tatttcaatc gtggcaagaa gtaaaccaga tagtaaaatg
   115081 agaatagttt cagctctgca aaagagcggg gatgttgttg cagtaacagg tgatggtata
   115141 aatgatgctc cagcactttc aaaagcagat gttggtatag caatgggtat atctggtaca
   115201 gaggtatcta aaaacgcagc agacataatt ttaactgatg atagttttag taccattgta
   115261 aaaggtatta aatggggtag aggaatttat gataacttcc aaagattcgt tcaattccaa
   115321 ttaactgtaa atgtaattgc atttttagtg gctataatat ctcaagttat gggacaagag
   115381 atgccattta ctacaataca attattatgg gtaaacataa ttatggatgg accaccagca
   115441 ctagcattag gtttagagcc agttagagac catgtgttaa atagaaaacc tgttgataga
   115501 aaagccaata taatttctaa gtcaatggtg tatacaatag tattaaatgc attttatata
   115561 acagcaatac taatgttaca atctacattt aatttcttag gagttgatga agctcataag
   115621 ggaacagtaa tgtttgcgtt atttgctttt agcgcactgt ttaatgcatt taactgtaga
   115681 gagtttaatg cagatagtat cttccctaat tttacacata acaaattagc actacaaata
   115741 atagtgttga caggaattgc acaagtaata tttactcagc tattccaaga tttctttaac
   115801 tctgtagcaa tggattttat gacatgggta aaagttttat gtgtagcagc aagtgtaatt
   115861 gtggttaatg aagttgtaaa atgtataata agactggtaa aaccaaaaaa gactgcttaa
   115921 aacaaatttt ttagaagaaa acagactgac tcaaaatatg aattttgggt cagttctgaa
   115981 taaacattta aattgggagg atagttatgg gtgactcaaa ggtatttgaa aaaatattct
   116041 ccagccaatc agatagagga aattacactc cttcaaaggg atatctaagt tattttattt
   116101 cgtatattgg tttagaagat gaagttttgt acaatctcga gatatttaag acaaaacaaa
   116161 atattgatag caaaaaagat attgctttat ttactgatgt tatagcaaat cctagtgatt
   116221 ttgatattat aaattatttt aaaagtggac ttcaaaaata tagaactagc atggaagatg
   116281 tagatataaa tattttggga tttgaagaga ttgattataa aataaagcaa gcaatggata
   116341 gagtgttaaa agaagaggaa aaagaattta ctaatgatag agttaaacaa aattttatag
   116401 tgaaaataat ggcatggata aaaatttata tcggtgcttt agatataaat aaaaatgaag
   116461 ctccaaaagt aatattttat ggagatataa aaaaacatga agtttattta ctcttaatat
   116521 tatacttggc aggttttgat gttttatatc ttaatccaaa ttcaaagagt aatatagata
   116581 ttttaaaatc agaaagatac aatatagagt ttgaagaagc caacataata gaagaaaaaa
   116641 tttcttttga agaaagggtt attttagggg aaaaaataga taaaagttct gtaaaaaaag
   116701 cttttactgt tggggcagaa gcatcaaagc gtataagtga ggaattgtta aatgatgcag
   116761 gatttataaa accttggcaa ctccaagata gaaaaataaa aaatctactt ctaagttcaa
   116821 ctgttgatga aatatcaata tactggaatc aaccacttaa attaagacca ggatttaagt
   116881 ttaatgatgc tattgtagaa gctccaaatt ttctttctaa gattaatgga atatataatg
   116941 ataagaatga atatattaag tttttagatt tattaagaga ttcggaaagt tcaacattta
   117001 ttgaatttaa tggagatgta gatagatttt caaaagcttt tacgagagaa gcttttagtt
   117061 tatccttttt attggattca aaaggtgtaa tagataaaaa ctctgtttta aataataaag
   117121 attattctat atcaacacta gcattgaatc aacaaattat gattttagag aaagtggaag
   117181 agttgttaga aggaagtatg tttttgaatg gtttaagtgg agaagacaag ataaaaggtc
   117241 tatttacagt acttcacatg gataagaaat ttgttcatat gatgaacaat ttcgattact
   117301 cacttataaa cccaaaattg attatataca tgtacaagag tattgtattt gataaagaaa
   117361 tagtttttct tatgctttta cttagtaaga taggatttga tattatcata ttatgtccag
   117421 gaggagaaag caatatagag aatgttataa ataaccaatt gattgatata cacagattgg
   117481 ataaaatggt atatgacctt aaattaaatt cgcttgaaaa tgatatacct ttacttaaaa
   117541 aaatttttgg aaagaggaga cgattttaga tggggataaa tataaatagt ttttcaaaag
   117601 ataagaactc tgtagaggtt actgagaatt tgcctacagc agttcaagaa gaaaacttcg
   117661 atataatgga atatacaaat aataaaaaaa atgaactgag aaagtctaag gaagttgagg
   117721 cattgacatc ccttatagaa gtagaaaatc cagatacgat tttacagttt ggtaggaaag
   117781 catctgaagg agtagcaaga gtttctgata gccttttaaa tacaataaaa ttaaatagaa
   117841 atgaagaaaa ttctaaaatg ctggttcatt taactaaaat aatggataag tttgatttag
   117901 acgattttca agaaactaag gaaccaaatt tcgttcaaaa acttttcaaa aaagctaata
   117961 atgccattga aatgatgttt caaaagtatg aaacattggg aggagaagtt gagaaaattc
   118021 aaattgagct tgagcaatac gaaagagata tagcactttc taataagcaa ataggtgcta
   118081 tgttaaatga aaactttgag ttttataatg aacttcaaaa atatattgtt gctggagaaa
   118141 tggcaataga agaaatggat aatgaaatac tacctttctt taaacaaaaa tcagagacta
   118201 gtggagacca aatggatgtt gtcaattatc aagaactatt aaaagtttat gatatgttaa
   118261 atcaaagagt ctatgattta agaatagcag aaaatatagc tatccaaaca atacctatgc
   118321 ttagaggtat gcaacataat aattatggtt taattagaaa aataaatagt gcatttgtcg
   118381 taactttacc agtatttaaa caatgtttat ctcaagctat attacttaaa aagcaagaat
   118441 tacaagcaaa atctctaaaa gcacttgatg acaaaactaa tgaattattg cttagaaatg
   118501 cacaaaatgt aagtactcaa agtgcacaaa tagctagaat ggctggaaca agttctgttc
   118561 aaatagaaac attggaaaaa atgtacaata ctatcaagtc tggtatagat gaaactatga
   118621 gaatagaaga aaacaataga gctttaatta aggataatac aaagagattg gaagaattaa
   118681 atacgactat aatttataat aagtagtatt atattaaggg ctaatttgta taaagttggc
   118741 cctttctatg tatatgagga ggctagacat tgaaatattt cgattatatc tgcaaagatg
   118801 atttggagag aatttttttg aaggagccag aagactttag tgctaagact gaaaaagatg
   118861 tgttgaaata tgcactgggc gcttttttat acgttccagc tactcaatat aatatgattt
   118921 ataagagtat tataggggat gttaagggag ttagaccatt agctatttgt ttagaagatg
   118981 ctgttggagt aaatggagag ttagaggcta tagaaaatct tagattaatt ttaaaaaata
   119041 ttagcaatga aagtataact aataaagatg gaataccact aatttttgta agaataaaag
   119101 atgtggagca actgttgaga attaaagaga ttataattaa aaatagacat tctataacag
   119161 gaatattaat tcctaaagca aattcggagt tgattgaaaa ttgtatagaa gctttagatt
   119221 ctatgaatct tcaagatatg tatgttattc caataataga gacaagagaa tttatatata
   119281 atgaaaaaaa agaacttagt tttactaatt tgtacaatgc tattttaaga cataagtcaa
   119341 gaatattaag cattagagta ggcataactg atatattagg gatgtatggt ataaggagag
   119401 ataaaaactt ctctatatat aataatttga tttgttcttc atttatatta gatataatca
   119461 catatcttca aagaccagag ttagatatac ctataagtgg tggagtatca gaattttttg
   119521 atatgacaaa taaggatata agaaataagt atatagaaga aatattattg gataaatatc
   119581 atggattaat tggaaagacc gtaattcatc caatgcaaat tcaaattgta caagcgctat
   119641 ctacagtatc atatgaagat tttactgatg ctttggatat actggatagt acagacagta
   119701 agtatggtgt gagcaagggt gtattaggag agagaatgaa tgaaacaaat ccacattttt
   119761 tatgggctaa aaaaacattg attctatcta aaatatatgg tgtattaaat aaaggagtag
   119821 actatgaaga attgcttaaa ttttaattgt gagattgaca ttattgataa tccattgaat
   119881 ttagaactaa atgatttttt agacgtagga ataagaaata atagcaaaag acgttttttg
   119941 tttatctcaa agaaactcgg taaacattta gcatgtaagc caagtgagat ggataatttg
   120001 ggaaaattaa tggctacaat ttataatgaa aaaaataagg aagaatcaaa tggtactgtt
   120061 atagcttttg ctgaaactgg tacagctgtt gggcatagtt tttttgatta cttatgtgga
   120121 gattatgaat ttattcatac tactagagag cagtttgacg agttagaaaa tctggaattt
   120181 ttagaggaac attcccatgc aacagaccag aatttatact ttggtatgct taacaacttt
   120241 aaatttggag atgagataat attggttgat gatgagatta ccacagccaa tacatgcatg
   120301 aatataatta ggaaaattca aagcatttat cctaaaaaga aatacactat atgctcaata
   120361 ctcaattggg taagtgatga aaatttaagt aaagttactc gtttagaaag agagctaaat
   120421 tgtaagatag attttgtata cttatttaaa ggaaacttta aattttatat agatgaagat
   120481 attatttcaa attacaacga taattatagt attactaaat tagagactat ttcaagtgat
   120541 aaagtaaatt tagtagtaaa tcatatttat gttgatttag aagattatat tggaaataag
   120601 aaatatgtaa aatatacagg aagatttgga attaatagaa gagaacaatt tagattaaaa
   120661 gaaatcgtta agagagaaag taaaaaaata actatggcca gtaaagaatc tttaaaaaat
   120721 gaaaaagaaa agattctatt tttaggtact gaagaattta tgtatatacc tatgctgttt
   120781 gcaaaagaaa aagaaaatca atatgatata tactatcatt caacaacaag aagtccaatt
   120841 attaatattg ataagaagca ttatcctatt aaaagtaaat ttatgctaaa gagtttttat
   120901 aatatagata ttcaaaatta tatttacaat atagataaac ataatttttc taagtgttat
   120961 ttatttgtag agctgaataa aagtgaaaat tcttatctag aatttattga tataattaaa
   121021 aaaacaagta taaaagaatt aactatagta tgttgtagct aaagtgtttt aacaggataa
   121081 aatatatcac gattttaaga taggagttga gtcatatgag agattttagc acgtattcta
   121141 aagatgatgt tattttttta ttaaaagata tatcaaattt aattgaagaa gaaggaaata
   121201 aagaaagaga attaaaaata caaaatggta gacattattc agaaatgata ccaatagagt
   121261 atgaagttag tgaagattat ctgaatttat atcatgagaa actaagagaa aataaagata
   121321 aacttgcatt ttctatagga gttatgtgtg aaaaaataat taaaaaaaat ggaaatgatg
   121381 tagtactagt ttcacttgct agagcaggaa cacctattgg tattttggca aaaagatata
   121441 taagaagcaa gtataatgta agtttacctc actatacaat ctctataata agagataagg
   121501 gaatagatat gaatgcaatt gaatatatag taaagaatca tccgagctca aaaattcaat
   121561 ttttagatgg atggactggt aagggaacta tatcaaaaga acttgaaaaa gcatgtgatg
   121621 aacttaatgt taaatttaaa aaacattttg actcaacact tgctgtatta gctgaccctg
   121681 ctggatattc aggactttat ggaattagag aagatttctt aataccaagt gcatgtttaa
   121741 attcaaccgt ttctggttta gtaagtagaa ctgtactaag agaggattta attggtaaaa
   121801 atgactttca tggagctaag ttttatagac atttaaaaga taaagatgaa tctatgaact
   121861 atatcgaaac tatagaagaa tgttttaaaa atcaatttaa gaatatatct gatgaagttg
   121921 aaaattggga aagtgacatt ataacaagag atggatactt tgatgtttta aatataaaag
   121981 aaaagtataa cataacagat attaacttta tcaaaccagg tgtaggggaa acgacaaggg
   122041 ttttacttag aagagttccg tataagattc ttgttaaaga cttaaatgat aaatctttag
   122101 accatatatt catattagct aaggagaaaa atgttgaagt tgaacaaatg gatctaaaag
   122161 cctataaatg ttgtggaata ataaaaaata tgaaagatat ttaggaaata tattagacag
   122221 gagaatattg aatgattgtt ttttcagatt tggacaggag tatcatttac tccaataaat
   122281 ttttaaatgc tgatagtaaa tatgctaata tagaaattta tagggaaaaa gaaatatctt
   122341 atatatcttt agatactata aatttaataa agcaaataca atattatggt atgtttatac
   122401 ctataactac tagaacagtg gagcaattta agcgtataga atttaataaa tatgggattt
   122461 attttccttg gagtataact tcaaatggag gagttatact taaagataat gaaatattga
   122521 aatcatggag tgaaaaaata gataaactaa aatctgatta tgagcccatt gaaagtatga
   122581 ttcataaatt taaagactat ttgaatgtag atggaataac taattttaaa gttgcagaag
   122641 atacattttt ttatatagtt gttgatttct caagatttaa tttggattca atcaaagaat
   122701 atacaaatat attggaatca aaaaattgga agttttatgt gagtggcaga aaaatatatt
   122761 ttataccaaa agaaatttca aaagaaaatg ctataaaata cttgactaaa gaattaggaa
   122821 tagaatattt ttatacggtt ggagattcta ttatggacta tggtatgctt aatatctcaa
   122881 ataaatccta tgtattgaag catggtgata taaataaaaa tgaaatagaa aattcattta
   122941 tatcaagttc tttcaatgga atgagtggaa ctgaagagat actatctaac attttagacg
   123001 agaactgcct acttaatata taatgactga tatataaata ataaactaga aaaatctgaa
   123061 ataaattata gtaaagttta tcatactaat ttatttcaga tttttatcaa tttatattta
   123121 agtaagaact caatatgtta aaatgaaggt ggagtcattg cccagactga gatacatacc
   123181 tcatcatcat aattttcata cacatgtggt atagtactgt taaaataaaa actatctcct
   123241 tcctccaata gatattcctt atttccaagt gttatcttca ttttaccttt tattatatag
   123301 ccacattctt ctccttcatg tgtcacaaat tcactgtttt tttgtgtatg accatctagc
   123361 gtaacaagta taaattctat ttttttccca gataaattag gaacaagaag ttcataaaat
   123421 tttgtagaat cattagttac tatttttttt cgattatttt tctttactat tatatcagag
   123481 tcctctcttc caatctcttc aaaaaaataa cctatattta tatcaagagc ttttgatatt
   123541 ttccacattg ctacaataga tggaacaacc atattacgct caatttgact tattaagcct
   123601 gtacttaaat ctgaattttt tgctaaagta gagatactta tatttttaga ttttctaaga
   123661 gatctaattt tgcttccaac atctatattc attagataca aaccccctca gacatgatta
   123721 taacatataa tttataaaga ttaataaaat aaaaaaaagt tttacaatac aagtattttt
   123781 tatgttatat tgaattttct gaaaagatgc attataatag tattaatatt caatatattg
   123841 aatattgata atgatatttt aatttaatga aatggaggta attaagatga agagttttgt
   123901 aagtcctgat aatatttggg tattatgggc agttgtaact ggatgggcag catttagtat
   123961 ttacttggaa caaaagtaca attgggcatc aaaagtgtcg ggagcaataa tagctcttgt
   124021 aggagcaatg ttattatcaa atctaaatat tataccagta gagtctgttg tatatgacca
   124081 agtatgggga tatgttgttc ctttagccat agctttattg ttatatcaat gtaatattaa
   124141 aaagatatgg aaagaaagtg gaagattgct cattatattt cttgtaggtt ctgtaggaac
   124201 tgtacttgga gctatgattg gatttttagc attaaaaaat gtagtaccag atttaaatat
   124261 tgttgcagct atgatgacag gttcttatat aggtggaaat gtaaactttg ctgctatgtc
   124321 aggggcgttt gatgcgccag gagaattagt atcagcaaca gttgtagcag ataatctttt
   124381 aatggcatta tatttctttg tcttaatagc tataccatca attggatttt ttagaaaaca
   124441 ttttaaacat ccacatgtag atgaaatgga aagcataggt ataactgaag gagaaacagt
   124501 agcagcaaat tattggggaa gaaaagaaat atctttaaaa gatatagcaa tagccattgg
   124561 tagcgccttt ataattgttg cagtatctgt agaactatca acttggttta aagctataat
   124621 accattatca aatccttttt tagcaatgtt aaatacttta tttggaaatc aatatctaat
   124681 aataactact ttgactatgt tgtttgccac atttatgcct aatttctttg gtgatataaa
   124741 aggagcacag gaattgggta catttttaat atatatattc tttgttgtag taggtgttcc
   124801 tgcttcaata acattaataa ttcaaaaatc accattacta cttttatact gcggaataat
   124861 ggtactaata aacatgctag ttacatttat agttgcaaaa atatttaagt ttagtttaga
   124921 agaagctatt cttgcatcta atgcaaatat tggtggtcct acaacagcag cagctatggc
   124981 aatatcaaaa ggatggtcta agctagtagg gccaatactt atagttggaa catttggata
   125041 catagtcggt aattattttg gtcttttagt aggaaatatt ttgatataat tttacgtgaa
   125101 aaaaagttgt tttttagaaa gatttttatt tattagaaag atttttattt aattggaggt
   125161 tgttatgatt ttcgatggac attcagatac ttgggcagat gtaacaataa gaaggcttaa
   125221 cggggaaaaa gatgtattta gaagaatcca tcttgataat tttaaaagag caaatataga
   125281 aggagctatt tttgtaatat ggatagaccc accatatgat aaagagcctg aaaaaagagt
   125341 taaacaaatt ataagctcta taaaagatga aattgaagat atgaaagatg ttgtaaacat
   125401 agtaaaaaaa tattcagata tagataaagg tataagtgaa aacaaaataa atattttaat
   125461 tggtcttgaa ggattaagcc atattggaag aaatatagat ttactagatt atttttataa
   125521 agaagttggt gcaagacatg catcattaac ttggaatgaa cagaatgaac ttgctacagg
   125581 atgtttaggg gatgaaaatc gtggtttaac tgaaataggt aaaaaagcag tcaataaaat
   125641 ggaaaaattg ggcatgatag tagatgtgtc acatttaaat gaaaaatcat tttgggattt
   125701 aatgtctgtt gcaagtaagc cagttatagc ttctcattct aatgctagga gtttatgtga
   125761 tgctaaaaga aatcttacag ataatcaatt aaaagaaatt tcaaatacag gtggattagt
   125821 tgggataaat agttttagag gatttactaa tagtaatcct aagaagcaag atttaataca
   125881 tttggttgac catatagact atatggtaaa tcttataggt atagaacatg tatcttttgg
   125941 ttttgatttt agtgattact tagggaaaga gactataggt tcttttactg gaaatgctag
   126001 tgtgccaagt gtagatggtc ttgaaagcac acatacagca cagaacatag tagtagagct
   126061 tgaaaataga ggttataaaa agaaagatat agatttaatc tctagtggta atttttatag
   126121 gctctttaaa gatatactaa aataatataa taaagaactt aaatttataa aatagtatat
   126181 ttatacaata atatctacat atttaaattg gagttcataa tttattaaat taaattttaa
   126241 tgttactaga agtttcaatt ctagtaacat tttttatgtt aaaaatagat atagatatat
   126301 atatatattg acaatgataa ttattattga taaactataa aagtgaaaat gataataatt
   126361 ttcattttaa ttaataaaag atttttaagg agggagaatg aaaaaaaggt atttagtcat
   126421 aggaataata attttgtctt atttttcttt atttatagga gctgaagata taaatataat
   126481 gcatatattt gcaaaaaatc agcataagct tatgatattt atcatgagta gggtaccaag
   126541 attaataagt atattgattg ctggtgtagg aatgagcata gcaggtctta taatgcaaca
   126601 gataagtaag aataaatttg tatcacctac aacaggagct acaatagatg cagcacaatt
   126661 tgggatagta atatgtatgc ttttagtacc aactgcctct atttttacaa agacaataat
   126721 agcatttgta ttttctcttg tagggacttt tacgtttatg aaaataatag ggaagttaca
   126781 atttaaaaat ataatctttg taccattagt aggtataatg tttggaaata taataggttc
   126841 tatgacggat tttatcgcgt ataaatacga tttgagtcaa aatgttagtt cttggatgca
   126901 aggtgacttt tctatgatac ttaaaggaaa ttatgagata ttatatatca caatacccct
   126961 tataatatta gcatatattt atgcaaataa atttactgtt gttggtatgg gtatggattt
   127021 tgcgacaaac ttaggtctta gttacaaaag aattgtcaat ataggtctga taatagtagc
   127081 acttgttaca gtatgtgtag tcgttacagc tggtaatatc ccttttatag gtctaatagt
   127141 tcccaatatc gtatccttgt atatgggtga taatataaga gcaagcatat ggtatactgg
   127201 tttacttgga gcggtatttg tacttatatg tgatattttt ggaagaatta ttatttatcc
   127261 atatgaaata tctataggac ttacagttgg agttatagga agtatactat tcctttattt
   127321 aatattaagg aggaatgtga atgaagctta gtctcaatca aaaaatttac tttgtaagta
   127381 tattactatt catatcaata gcacttttta taatttatgg aatagacatg aatcatttag
   127441 aatatgcatt atcacaaaga ataccaaaaa tatttgctat ggtattaggt ggaggatgta
   127501 tagcatttac tactgtagtg tttcaaacaa ttacaaacaa tcaaatatta acaccaagtg
   127561 tactaggttt agattcattg tatgtaatga ttcaaactat aatagtattc atatttggtt
   127621 caagcagtag tctgattata aatgaaaatt ataattttat tattaatgta gctatgatga
   127681 ttggagcttc attgttatta tataagatgt tatttgaaaa aaataaaagt aatattttct
   127741 ttttaatcct agtaggaatg atatttggaa ccttatttaa aagtgcaaca acatttattc
   127801 aggtaatgat agacccgaat gaatttttag ctttacaaac tagtataatg gcaagtttaa
   127861 acaatataaa cactaatgta ttgttaatag catttataat aattattgcc ataatacctt
   127921 ttatatatga tgaaataaag tatttagatg tattgtcgtt aggtaaagaa caagcaatta
   127981 atttaggtgt agattttgat aaggcagtta aaaaaatgat aatattaata gcaattttag
   128041 tctcaatatc aacagcactt attggaccta tgacattttt aggactttta cttgctaata
   128101 taacaagaga aatttttaaa acatataagc atacatactt gatttcgggt tctatgttga
   128161 tagggatgat tacattgata ataggtcaat tttttataca acatgtattt aagtttgata
   128221 cgactttaag tgtagtaata aattttatag gaggaattta ctttattcaa ttactattaa
   128281 agggggcaaa tagatgatag agataaaaaa tatatttaaa agatataaga ataaaaatgt
   128341 tgtagatgat gtctctttta gtatagaaaa gggaaagata acatctttta taggaccaaa
   128401 tggagctgga aaaagtacag tactatcaat agttacaagg cttataggag gtgatggcgg
   128461 agaagtaata atagaaggga aaagcttgac taattatagc aataaagaat tagcaaaaaa
   128521 aatagctatt cttaaacaat ctaacaatat aactttaaag cttacaataa gagaattagt
   128581 tggatttgga agatttccat atagtgaagg taatctaact aaagaggatg aaaattatat
   128641 tgatgaagca atagaatata tgaagttgac tgatatacaa cataagtatt tagatgaatt
   128701 gagtggaggt caaagacaaa gagcttatat agcaatggta atagctcaag atacagagta
   128761 catattactt gatgaaccac tgaacaattt ggatatgaac cattccgtac agatgatgaa
   128821 ggtacttaga ggtctttgtg atgagttaga taagactata gtattagtaa tgcatgatat
   128881 aaattttgca tcatgttatt cagataatat agttgcatta aaaaatggaa aagttgaaaa
   128941 agtaggtcgt acagatgaga tagtaaatga aaaagtttta gaagatattt atgagatgaa
   129001 ttttaacatt aagaatataa atggaaatcg aatctgtatt tatttttaaa atattgtata
   129061 tgaaaataag cttgctatat gattttttat aaagttttta aattaaaata aagattaata
   129121 ggagagagga aaatattgat atgaataaaa aagcagcaat agtagcagca gtagctatta
   129181 taggattagt gacagtgttt gcattaggtg gaagtaaaaa gaatgaatca aaaacatcag
   129241 aaaattcaaa taataccata aagataactc ataacttggg agaaacagat gtaaaattaa
   129301 atcctaaaaa agtagtagta tttgattatt cggctttaga tacaatggat gcattaggtg
   129361 tagctgagaa tttagtagga cttccaaaag cgagtttacc agcatcttta gaaaaatata
   129421 aggataagaa gtatgcagat ttaggaggtt taaaagaacc agatttagaa ggtataaagt
   129481 cggcaaatcc agatttaatt ataataaatg gaagacaaga agatttttat gagcaattgt
   129541 caaaaatagc accaacaata agtacaagta aagatgataa gaagtactta gaatctgtta
   129601 aaaataatat agacaaaata gcaaaaatat ttggagtaga agaaaaagca aatcaagaat
   129661 ttagtaaaat tgaaaagaaa atagaaactt tgaataaaaa agtaacagat aaaaatttaa
   129721 atgctttaac tataatggta aatgaaggta atttaagtgt atttggtgaa gaatcaagat
   129781 ttagtatatt atacaatagt tttggatttg aaaataaaga taaaaatata aaagaatcaa
   129841 gtcatggaca aaatattact tttgaatata tagctaaaca aaatccagaa gttatgttcg
   129901 ttatagatag aggaatagct actggtagtg atgtaaaaga aagctcaact gcaaaatctg
   129961 ttttgaacaa tgatataata aaatctatgg atgcatataa gaatgataat ataatatatt
   130021 tagattcacc aacatggtat gtaaatgatg gtggtctagc atctttaaat aaaatgatag
   130081 atgatgcttc aaaagcggta aattaataat ccgatataat caaaatgtat tttttgtaaa
   130141 atgattatca aataaactag gagtttttaa gaactcctag tttatttttt gcataataaa
   130201 gatatagttt aaacaataat attatttata ataagataaa tctattcaaa atctaataaa
   130261 atatgaagtt atactagaca aaaagaat
//
LOCUS       DACTZW010000002        96310 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.002, whole genome shotgun sequence.
ACCESSION   DACTZW010000002 DACTZW010000000
VERSION     DACTZW010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 96310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 96310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..96310
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.002"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            110..301
                     /locus_tag="JAM15_00580"
     CDS             110..301
                     /locus_tag="JAM15_00580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HAT6796766.1"
                     /translation="MKKVALILAIIGALNWGAIGILGTDLIGSIFGGTYEMVSRIIYF
                     IVGLAGLYLIPSLMSDDRE"
     gene            456..1865
                     /locus_tag="JAM15_00585"
     CDS             456..1865
                     /locus_tag="JAM15_00585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HAT6796767.1"
                     /translation="MFIINELNKIVNEEVISFHMPGHKKGQVYKKLGYKDILKNLYKM
                     DTTEILGTDNLHFPEGIIKNSQKKASRVFKSDYTCYLVNGSSCGIQSAIMSVCSPKSK
                     IITNRDCHQSVINGCILGDIDIEYVPCEISEETNVLKGISISNVIDIIDKNLDAKAVL
                     LTYPTYYGMTYDLEYICNYAHSKKMVVIVDEAHGAHLGLSERLPKTALEQGADIVVQS
                     THKTLPAFTQSSMIHIQGDRVDIDKILNMLRITESSSPSYLLLSSLELAVDIYENKGK
                     ELMEELLNNIRIFKDKVDSNINIYDTNDKTKIFISSKNMGLTGYELENILRNKYNIQV
                     ELSNYYGVLLICTIGNTAEDFSSLETALNNVVKEDFKFEKLENKKYPVVIPKKILTPR
                     EAFYKTKKSVKIYDSIGKICGECIVPYPPGISVISPGEVISKEIIDYLMFCHSKGMIV
                     SGLKDVDLNFIQVIDLEDI"
     gene            1996..2685
                     /locus_tag="JAM15_00590"
     CDS             1996..2685
                     /locus_tag="JAM15_00590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAT6796768.1"
                     /translation="MKGKLIIIESGSDASGKATQTEILYERLKKEGYMIKKVEYPNYE
                     SPSSALVKMYLKGDFGKNASDVDPYIASTFFTADRYASFKTDWEEFYNKGGIIIADRY
                     TTSNMVHQASKMDICDREEYLNWLADYEFNLFKIPQPDCVIFLDVPIEFSEKLMENRK
                     NKITGEEKKDIHESDIEYLEKSYNNALYIADKYDWKKINCVLDNKLRSIESIHNEIYK
                     IVLDSIKPMER"
     gene            2688..3623
                     /locus_tag="JAM15_00595"
     CDS             2688..3623
                     /locus_tag="JAM15_00595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HAT6796769.1"
                     /translation="MYFENIIGQDFAKKYLTNSIKKNKLNNAYMFEGMDGIGKKKFAD
                     ELSKLLLDYENLENSPDYVLIKPDGNSIKIAQIRNLQSDIVIRPHKDYKIYIINNAEK
                     MTVEAQNALLKTLEEPPNYAIIILVTNNKESLLETIKSRCDIIKFSPIPIEDLKRYLI
                     NTGIEEERAQLLAIFSRGSIENALNLSQSSEFSMMREDIQQYIQIMLDKNIVEILNIP
                     NNMEKYRGKIIALLDMMINYFRDIILLKENVNKNMLINVDKLVFIQNMSGKISYSQLS
                     KIIDIIEDAKSKIKSNCNFNISIQVMSLNIYEVIK"
     gene            3620..4513
                     /locus_tag="JAM15_00600"
     CDS             3620..4513
                     /locus_tag="JAM15_00600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HAT6796770.1"
                     /translation="MIKIVGIRFKSAGKIYYFDPVDFNIEQDMDVVVETARGLEYGKV
                     VVGPKDMDESELVSPLKPIIRIATEEDKKVYLENKEKAKETFELCQQKIKEHELTMFL
                     IDCEYTFDRNKLIFYFTAEGRIDFRELVKDLAAIFKTRIELRQIGVRDEAKSIGGLGP
                     CGRKLCCSSWLGDFQPVSIKMAKDQSLSLNPTKISGICGRLFCCLKYEHDVYSEAIEK
                     MPVVGALVQSDDGKGKVVEVNPLLEQIKVEFQDKTVKIYTREDIKILREPKKCDGCGG
                     KCKDNDGLDEATLRELKKLED"
     gene            4591..5337
                     /locus_tag="JAM15_00605"
     CDS             4591..5337
                     /locus_tag="JAM15_00605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HAT6796771.1"
                     /translation="MQLKDSERIDDLQLKGLKIIQDTNGFCFGIDAVLLANFTKIKKD
                     AKVVDLGTGTGIIPILIAGKSEAKKIIGVEIQEDVYEMATRSIKLNGLEERVEIINED
                     IKYIDKVLDINGYHVVTSNPPYMHIDGIKNPNDKKAISRHEVRCNLEDVIRAASRLVM
                     PRGKFFMIHRPTRLVDIITLGRKYKLEPKVIQFVHPRPQKAPNLVLVQFVKDGRPELK
                     ILDPLYVYGEDGNYTKELKAIYNNKDIGEL"
     gene            5338..6171
                     /gene="rsmI"
                     /locus_tag="JAM15_00610"
     CDS             5338..6171
                     /gene="rsmI"
                     /locus_tag="JAM15_00610"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018591996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HAT6796772.1"
                     /translation="MSGKLYICPTPIGNLEDITYRTLRTLKEVDLIAAEDTRHSIKLL
                     NHFEISKPLTSYHEHNKDSKGDYLINKLIDGENIALISDAGMPGISDPGEEIIKQAIQ
                     NNIEIEVLPGATAFVTALVGSGMDTHRFVFEGFLDRDKKVRKAQLEELKEESRTIIFY
                     ESPHRLKDTLKDMLKILGNRNISINRELTKKYQEIIRENIETTIKIFEEKEVRGEFVL
                     IVEGFHGEKSKKENYDGLTDREYVLKLIESGMNKKDAIKIVCKDRKLKKDVVYKQVLD
                     L"
     gene            6194..6898
                     /locus_tag="JAM15_00615"
     CDS             6194..6898
                     /locus_tag="JAM15_00615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAT6796773.1"
                     /translation="MEIGKIIIESLKREDTHKIFIELDNKHELEKIIPKISCMKSVGE
                     CKYHVVNCFEHSINALKELEIVLNDKDFFPIHLRKHVSNYLNTYIEEGINKLHVLKLG
                     TFLHDIGKPDSMTLDETGRVHFTNHEKIGAQIIDNMGIKLELSTKTYRLISKYVRYHM
                     ILLSLYKKNDLSRKELINVFNLVDEDTIGVIMLGYADIVSTVKLLGKSGEVSVLKTYM
                     EYILTNYLYKSNYTHV"
     gene            complement(7086..7514)
                     /locus_tag="JAM15_00620"
     CDS             complement(7086..7514)
                     /locus_tag="JAM15_00620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007287587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HAT6796774.1"
                     /translation="MDVTDYRIIEILQDDGRISMKDLGKIVGLTSPAVSERVKRLEES
                     GVIEGYKAIVNPDSLGRVIKAFIHISLPSNGYTEFIESAAKDPRIVECHHITGDDCLL
                     LKVIVKDMYELENVIDTIKKIGSTKTSVILSTPIQAKSIL"
     gene            complement(7551..8981)
                     /locus_tag="JAM15_00625"
     CDS             complement(7551..8981)
                     /locus_tag="JAM15_00625"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HAT6796775.1"
                     /translation="MRNLTLLTDLYQLTMLNGYFEKNIHEDIVVFDMFFRKNACDGGY
                     TIVCGIDQVVEYIDNLHFSDEDLEYLKNLNLFSDKFLKFLKEFKFTGDIYAVEEGTIM
                     FPNEPLITVKAPLYQAQLIETALLTIVNFQSLIATKASRVCFAAQGDPVFEFGLRRAQ
                     GPDAGIYGARAAVVGGCAGTANVLAGKMFDIPIIGTQAHSWVQKFDNELEAFQAYADV
                     YPDKCLLLVDTYDVLNSGVPNAIKVFKNISEKGYKPMGIRLDSGDLAYLSKEAKKQLD
                     NAGFSDISITASNDLDEYTITSLKAEGATINSWGVGTKLITSFDSPSLGGVYKLAASC
                     EKGVLEPKIKISENPEKINNPGYKKVIRIYNEDNKAEADLIMLHDEVIDESKPLEIFH
                     PTYTWKTKVFTNYKVKELLKPLYIKGRCKYNKKAVLEIKNHVQYELSTIWEQYKRLSK
                     PHIYKVDLSRNLWYLKTQMIDSKKVL"
     gene            9113..9697
                     /locus_tag="JAM15_00630"
     CDS             9113..9697
                     /locus_tag="JAM15_00630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein A"
                     /protein_id="HAT6796776.1"
                     /translation="MIIIGKIWFYMVSIGIIGSLISKNMGELNKVILSETSKGIEFAI
                     SLAGIMALWMGIMNIAKESGLIEKIGQKLNPIMRRLFPSIPKGHKAMSYIVMNIALNM
                     LGAGNGATAFGLKAMSELQTLNNKKDTATNDMIMFMVINISSIQIIPFTIIKLRMDMG
                     AQNPSEIIFTTLFATIISTAVAIITCKFFQRRYR"
     gene            9713..10234
                     /locus_tag="JAM15_00635"
     CDS             9713..10234
                     /locus_tag="JAM15_00635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein"
                     /protein_id="HAT6796777.1"
                     /translation="MEIFSNLLIPIIILYIVVYGKYKKIDVYDSFVKGAIDGLKAAWD
                     ILPYIIGIFLAIGIFKTGKGLDMLEWLFTPIANMMSIPKELIGLISVKPLSGSGALGM
                     YSELANRVGIGSLVEKMGATIVGSSETIFYTMAIYYGSLKIKNTRHTLSCAMISHVAG
                     VIAAVFICYVIFV"
     misc_binding    10300..10546
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            10630..12567
                     /gene="metG"
                     /locus_tag="JAM15_00640"
     CDS             10630..12567
                     /gene="metG"
                     /locus_tag="JAM15_00640"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HAT6796778.1"
                     /translation="MSKPSFYVTTPIYYPSGGLHIGHTYSTVAADTIARFKRFCGYDV
                     KFLTGTDEHGEKIQKKAIEQGMSEIEYLDGMIKDIKALWNTMDISYDDFIRTTEKRHT
                     DIIQKIFTKLYEQGDIYKGEYEGRYCTPCESFWTESQLLEGNKCPDCGRETYLVKEES
                     YFFRLSKYEDRLKELFKDDSFCFPAARKNEMVANFLDKGLEDLSVTRTTFDWGIKVPF
                     DEKHVIYVWVDALCNYITALGYMTDNDEEFKKYWPANVQIVGKEIVRFHTIIWPALLM
                     ALGLEVPKQVFGHGWILFADDKMSKSKGNVVYPEPIIERYGIDTLKYFLLREFAFGQD
                     GSYTHRNFVTRINYDLANDLGNLISRTVAMVEKYNNGIIPTAKVSTDFDADLKEQAVS
                     TRENFEAEMDKMQFHEALESVWKLVRRTNKYIDETMPWALAKDETKKDELDTVLYNLC
                     ESIRIIATLINPIMNETANKIYEHIGIKGQDDITTWESTKTFGLIGENVKVFKGEPLF
                     PRLDVEKEIEELTKMFSGKPPVEEKPLEHKEEITIDDLDKIELRVGKIISCEKHPKAN
                     KLLVSQVKIGPETRQIVSGIAEYYKPEDLVGKEVTVVCNLKPVKLRGVESQGMILAAG
                     DDGDPYVLPFTQGAKDGCEVR"
     gene            12597..13367
                     /locus_tag="JAM15_00645"
     CDS             12597..13367
                     /locus_tag="JAM15_00645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HAT6796779.1"
                     /translation="MLFDSHAHLNDESFDEDRDELIGSLKDKGVDLVVNPGADIETSI
                     TAIELAKKYDFIYSAVGVHPHDVSKLDDTAIETLRKLATENEKVVAIGEIGLDYYYDY
                     SPREEQKEWFKKQIELANELKLPIIIHDRDAHGDTFEIIKNTKNPEIGCVLHCYSGNV
                     ELAREYVKMGCYISIPGTVTFKNNKKTREVVREIPLERLFIETDSPYMSPEPHRGKRN
                     NPSQVSFVADKIAQEKGICYEEVCRVTKENAKKFFNIK"
     gene            13705..14136
                     /gene="phnG"
                     /locus_tag="JAM15_00650"
     CDS             13705..14136
                     /gene="phnG"
                     /locus_tag="JAM15_00650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnG"
                     /protein_id="HAT6796780.1"
                     /translation="MYTVDSTKILINMNLEKLEKIYSMIKDTSSISIIKEPNLATVMV
                     RANESVKNTTFNLGEILVTECSVKVDESLGYGIVSENNNKKAIYLAVIDAVLHSNNSK
                     FDELKNYINKSVYEENLRYEQEIIDEFSLINKTKVQFNAMD"
     gene            14151..14726
                     /gene="phnH"
                     /locus_tag="JAM15_00655"
     CDS             14151..14726
                     /gene="phnH"
                     /locus_tag="JAM15_00655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnH"
                     /protein_id="HAT6796781.1"
                     /translation="MVNYTQEIYRKMLDSASFPGKLNNIDNINIENNTKLLNGAIGIA
                     ITLLDQEVTFYIENYTQKDIKNIRALTMSNQIDYRKSDYIFLDINSEVDILQIKIGSF
                     EYPDESATIVHQVNDLSTYSQTKYIKLDLSGPGIKSKNSIYINGIREEFIERLSTINK
                     DYPIGIDLILVDKKGEIAFIPRSSKLSWEVL"
     gene            14729..15814
                     /locus_tag="JAM15_00660"
     CDS             14729..15814
                     /locus_tag="JAM15_00660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-phosphorus lyase complex subunit PhnI"
                     /protein_id="HAT6796782.1"
                     /translation="MAYVAVKGGEEAILQAKNILEFYRVKGDSLPIDVKQIEEQMSYA
                     VDKVMSEGSLYNKELSALAIKQAQGDILEASFYVRALRSTMPRITYSEPINTEEMRIK
                     RRISATFKDIPGGQYLGATRDYENRILNVELLEEDEKKNRDFRDSFINELETVDEIPE
                     FTKISNIFRKENLLQEEVCENKLEEVIDDITRNSLRFPVSRSAKLQTLTRGESGVVSG
                     FAYAIVRGFGDEHPYISELRTGNVFIKVKHPIYEDEEIIIGDMLVTECEIVSKASQNK
                     TENSKTNSEDKNKMSLGYGLCMGNNENKAISMAILDKSLEPNSEKLAQDEEFVLLHID
                     GIDSLGFISHFKLPHYVDFKADVERIK"
     gene            15834..16703
                     /locus_tag="JAM15_00665"
     CDS             15834..16703
                     /locus_tag="JAM15_00665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate 5-phosphate
                     C-P-lyase PhnJ"
                     /protein_id="HAT6796783.1"
                     /translation="MIYNYGFLDENTKKEIRRKILKAISIPGYQVPFGSRELPIAKGW
                     GTGGLQLTLSLIGKNDVVKVIDQGSDDSTNACNIRSFIASVSNVETTKDTLEATLIQT
                     RHRIPEEKLKSNQILIFQVPIPETLRIVEPSEVETRRMHSEEDYSRMWVYLYEDIVRF
                     NDISIAVEYPCKVNDRYLMNPSPIPRFDIKKLNMSDNLFLFGAGREKRIYAIPPYTKV
                     EPLEFEDYKFEEEKFEGKYCSLCNSTNTFLDEVYDSDTNEKYYSCSDTSYCEKVRLKN
                     NSIDVTIGGTWNE"
     gene            16696..17562
                     /locus_tag="JAM15_00670"
     CDS             16696..17562
                     /locus_tag="JAM15_00670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6796784.1"
                     /translation="MSKINVSKRLENIDKQVLIGRNINLIYGDGCEKCFESTGYESNN
                     ICKYCGSIVACNNVNLELYEGEVLGIVGESGSGKSTLLKILFFQEHANSGEVYISHYN
                     KDTNILELSDQKKRYIKNHFMGIVYQNPHLGLNLDFSSGGNIAEKLLMANLYNVEKIR
                     DRGKELLIKTNIPVERIDHKPKYFSGGMQQRVQIAKALSNNPPILLLDEVTTGLDVSV
                     QAEVLDLIREIQRELKISMIVVSHDFDVIKMLADRTIVMKNGSVIESGLTDQIMEDPQ
                     HPYTQQLINSLL"
     gene            17603..18316
                     /locus_tag="JAM15_00675"
     CDS             17603..18316
                     /locus_tag="JAM15_00675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAT6796785.1"
                     /translation="MKETILEVNNFSKDFELHALNKTITACSNISFEVSKGEFLGIIG
                     KSGAGKSTILKSIYKTYIPTTGEIIFNSEIYGNVDLAKIGDREMINLRKKEIGYVSQF
                     LKTLPRITAIELVVHSLIESGFEKDCSYDMAKDILNQFEIKENLWDAYPNNFSGGEKL
                     RLNLAQAMVKKPRLLLLDEPTASLDNQSKIYVKEKMLELKSQGTTMIGIFHDIEFMET
                     VIDKTFTMAKGTISESGVA"
     gene            18317..19486
                     /locus_tag="JAM15_00680"
     CDS             18317..19486
                     /locus_tag="JAM15_00680"
                     /EC_number="3.6.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate
                     5-triphosphate diphosphatase"
                     /protein_id="HAT6796786.1"
                     /translation="MIKLIHNANIVLEDMILENGHLIIEGDTIKKVSNDRIDYAFDFN
                     EIDEIIDAKNLYVIPGIIDIHSDAIEKEIEPRPSTLLPFNMAFYELDKKLPANGITTV
                     YHSISLGDGVGVRSIDNSLKMIKNIDSYKNIDSKSINHKVHLRYEVLYYEGLEKVLEL
                     LDENKIDYLSIMDHSPGQGQYTNPTFYKEYATKVWGVTENYVDTWLDDLVNLHDNLDW
                     NKIANIIGIAKTKNINVASHDDDTLEKMDFIKNIGINVSEFPITLEVAKHSKKLGVLT
                     CLGAPNIVRGKSHNNNLKAMDAILEDCCDIVCSDYLPSAMIKSMCIVAERINNLNKAV
                     SLFTSNPAKAVGIYDERGSIKENKKADLVLVDIDSEYPKVVNTIVNGKTVYKREV"
     gene            19490..20326
                     /locus_tag="JAM15_00685"
     CDS             19490..20326
                     /locus_tag="JAM15_00685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HAT6796787.1"
                     /translation="MLTELHCHTSISDNNFTTEEIIKKAAEKNINILAITNHDTLSGL
                     DEALVLGEHYGITIIPGIEISAYDYKNRKRVHILGYNIDLNSQEIKNLCNPMVCDRHK
                     ASVKMVNKIIDLGYKISLEDVKKYSSKTGIFKQHIMKALIDKGYTDNIYSSLYKELFH
                     RGNGKVYVSLKYVDYRDAIKAIKNSGGICVLAHPGQMDNFSAIEEMVKVGLDGIEVYH
                     PSHNKELEKESLSYAKKYNLVVTGGSDYHGFYSQHNYELGSKSLNKEDLFKFRLALGG
                     VL"
     gene            20327..21322
                     /locus_tag="JAM15_00690"
     CDS             20327..21322
                     /locus_tag="JAM15_00690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAT6796788.1"
                     /translation="MSFLQVKNVGKSYGQVKVLKDISIDIEKGEFICLLGPSGCGKST
                     LLRIIAGLEDKHGGKIIINDKDMTNSPPESRNFGIVFQSYALFPNMNVYKNIAFGLEN
                     KNISKSNIDKKVKEVLDVVELSGYEKKYPSQLSGGQQQRVALARAIALEPDFLLLDEP
                     LSALDAKVRLKLREQIRSLHRKLGITTIMVTHDQEEALCLADKMVVMNRGEIIQVGTP
                     KEVYKNPETPFVADFIGTINFIDDGINKIAIRPEDIKVESNRDSKDKDIKVGEILDIE
                     FRGFNYRITVEYRSKQMKLDVVSKVAEQMKLCIGSKINFKIPKEGIVQYKSEGCA"
     gene            21340..23028
                     /locus_tag="JAM15_00695"
     CDS             21340..23028
                     /locus_tag="JAM15_00695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HAT6796789.1"
                     /translation="MITSKNKRRISDSTIQKYFLIFSVIVLIVFILFPLVSLLKNAFM
                     DTSGNFIGISNFSKYVENPSLIASFKNSIFVSTVSSLISLCLAFIYSYAITRTNIKFK
                     DFFKTMGMFPLFAPTMLYGISLIYLFGNKGIFTTMGLEVPLYGPLGIIISQILFTFPQ
                     AFLILSVALSMADYRLYEAADSLGASEFKKFCKITIPGIKYSLLSSFFVSFILAFTDF
                     GAAKVVGGNYNVLATDIYKQVVGQFNIPMGATVSMVMLIPVLIAFTLDKMASKKQGMT
                     ITAKSMPYKIKENKFRDRVFLIVCSFITLLIFILIFVSVIGSVIKLWPYNLSFTMEHY
                     TFKGILGSGIKTYLSSLKISTLTAIFGTIFVFFSAYMIEKVDKFPKLRQTAYLLSMIP
                     MALPGLVLGISYITFFNSASNPLNFLYGSTAILVIVNVVHFYSVCFITSNSSLKMLDK
                     EYELVAKSINIPFYKVFFNITVPMSITSILEIVVYYFVNSMVTVSALIFLYTPQTQTA
                     SISILKLDEIGYIGPSAAMAVLVLLTNIIVRLLYEFVTKKLKNNTQKWQQKDAA"
     gene            23040..24107
                     /locus_tag="JAM15_00700"
     CDS             23040..24107
                     /locus_tag="JAM15_00700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HAT6796790.1"
                     /translation="MKFKKLVSLGVLSTLLLSVITGCSTDSSGSDSKSDSKTKGDLTV
                     YTAIEEDSIEPYLATFKEKYPDIKLNIVRASTGDITARLLAEKDNPQADVVWGVAATS
                     LLVADDQGMLEPYAPKGSEEIESAFKDDKEVPSWVGIDAWMTGITVNTKELSDKNIPV
                     PSSYEDLIKPEYKGLISMPNPSSSGTGYLTVSALIQIMGEEKAWQYMDKLHENIGVYT
                     QSGSAPATSAASGEYPIGISFGYRGIKLKEEGYPVEVVFPKEGSGWDIEANALVKKDN
                     IKEASKVFLDWAISKDAMNEYSKNYAVTTISTGNPIPEGFPKKPLEQMIDNDLKSAAK
                     NREDILNKWISKYDGKTEKES"
     gene            24593..24709
                     /locus_tag="JAM15_00705"
     CDS             24593..24709
                     /locus_tag="JAM15_00705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter ATP-binding protein"
                     /protein_id="HAT6796791.1"
                     /translation="MDDDINMIAIRPEDIRVEFNRDFKEIIDLKLRPYRYKN"
     gene            24873..25940
                     /locus_tag="JAM15_00710"
     CDS             24873..25940
                     /locus_tag="JAM15_00710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HAT6796792.1"
                     /translation="MKFKKLVSLGILSTLLLSVITGCSNVSSGSNLKSNNKTKGELTV
                     YTAIEEDSIDTYLATFKEKYPDIKLNVLRLSVGGITARLLAEKDNPKADVLWGVAATS
                     LIILDDKEMLEPYAPKGFDKVNPAFKDDKKVPSWVGIDAWMTGITVNTKELKAKNISA
                     PNSYEDLIKPEYKDLISMPSPASSGTGYLTVSELIQIMGEEKAWQYMDKLHKNIGVYT
                     QSGSAPAILAASGEYPIGISFGNRGIKLKGEGYPVEVVFPKEGSGWEIESNALVKKDN
                     IKEASKVFLDWAISKDAMNEYSKNFAVTTIDTGNPVPEGFPKNPLEQMIDNDLKSAAR
                     NREAILNKWIEKYDGKTEKES"
     gene            26132..26662
                     /gene="rnmV"
                     /locus_tag="JAM15_00715"
     CDS             26132..26662
                     /gene="rnmV"
                     /locus_tag="JAM15_00715"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002846650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HAT6796793.1"
                     /translation="MIKEIIVVEGRDDVTAVKRAIDAELITTGGFGFPKGVMERIKAA
                     NERRGVIIFTDPDFAGEKIRKKIASEVPGCKHAFLPREEAKKDGDIGIENATPQSIIA
                     ALNKVRTENTEKRDEFKQVDLIRNGLIGNEEASLRRDALGKILGIGYGNAKQFLNRLN
                     NYGVEREEFIDALKQI"
     gene            26833..27702
                     /gene="rsmA"
                     /locus_tag="JAM15_00720"
     CDS             26833..27702
                     /gene="rsmA"
                     /locus_tag="JAM15_00720"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HAT6796794.1"
                     /translation="MDRLSSHNATKEVVQKYNFKFSKSLGQNFLIDSNIIDKILSGAR
                     ITRGDNIIEVGPGIGTLTREMGKIAEKVVAIEIDRNLIPILKDTLSDLDNTEVVNQDI
                     LKVDIQELVKDKLNGGPVKLVANLPYYITTPIVMKFLEEDIPVTDIVVMVQKEVADRM
                     NAIPGTKDYGALSIAVQYYCDTEIVAKAPRHMFIPQPNVDSTVIGLHVRDKRKYDVHN
                     EDIFFKTVKASFGQRRKTLLNSLGGLGFLNKDEIREILKEANIDEKRRGETLSIEEFS
                     VLSNIINTKVSSK"
     gene            27768..29048
                     /locus_tag="JAM15_00725"
     CDS             27768..29048
                     /locus_tag="JAM15_00725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796795.1"
                     /translation="MGSKRKFKRDYIILEAKDINFRYKERVLPKAFAKVEVNDEKAII
                     ALYVENLKYVKDGYKAVAIKDDHGLIDLGNIILNEQGRGEFVLDLEDSDDEIKGIALL
                     YERNIPLIGFKGNKLENYEDILFQEVEEEEYEEYEEYEEYEELEEDEEIEDNEESDRD
                     EDSEEEYIIEEYDEDEYEDYWEDDEDIEEGELKARTEVEDSGDEEIEEFNNYKEIENY
                     NRVKVQEEYIDIEYDEEEEEEEEVFEVNREEDRFVSSKPTKSKKVQKDQNNIEKIKRA
                     NGVSQGESGNKQTSTLLMPRQIKKGLKLFKEVKPFVTDYIDKTRWWKIEINPTTLCGY
                     TMPYLGYLNVLNYTMYSDAVLHSYKYRHYLFGVQYDEYNKRKHYIYAIPGNRNEQPDN
                     GSTGFLRYQACDNRTNSLGYWLCFIDSRQRNIVR"
     gene            29199..30314
                     /locus_tag="JAM15_00730"
     CDS             29199..30314
                     /locus_tag="JAM15_00730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HAT6796796.1"
                     /translation="MINEQRILNEFLELVQIDSLSLKEGNVAKVLVKKLEEIGCSVVI
                     DNAGEKANGETGNIIATLKGNKEGKKILFSSHMDTVTPGIGVKPIVDEANGIIKSDGT
                     TILGSDDKAGIAAILEGLRYINENNIEHTDIQVVFSICEECGLVGAKNLDYGKIDSEY
                     AFILDSGGSPGEIIVKAPAQDVINVKILGKTAHAGLEPEAGISAIMVAARAIENMNLL
                     RIDEETTANIGIINGGTATNIVTGEVNIVAEARSLKENKLDVQTKHMVETFEKAAKDF
                     GAQIEIDVNRAYTPIDVSEDSEIIKLAKKAFSNLGIEGHTESTGGGSDTNILSKNGIE
                     AITLGIGMKNAHTLSEHIAIKDLYDSAKMVVEIIKEA"
     gene            30500..31396
                     /locus_tag="JAM15_00735"
     CDS             30500..31396
                     /locus_tag="JAM15_00735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAT6796797.1"
                     /translation="METRYEEANKITIQSILWNVVLTIIKVIAGVIGNSSAMIADGLH
                     SASDIISSIGVLIGNYVSSRPGDREHNYGHEKAETLVSFVLSILLIFVSITIGIEAIK
                     SLFNLDALSVPSILPLVVSVISILIKEYQYRITIKVAKKINSPALKADAWHHRSDALS
                     SVAAFIGIGGSILGFKPLDPIASIVVAIFVAKVGISILISSVNELMDVSVDEEEIKEL
                     KFIVADTEGVKNLGDIKTRKHGAMAYVDLTICVDENLTVKQGHDIATKLEKHIIKHME
                     FVKGITVHVEPCTNCQGNKCNN"
     gene            31466..32263
                     /locus_tag="JAM15_00740"
     CDS             31466..32263
                     /locus_tag="JAM15_00740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796798.1"
                     /translation="MSKKRKLKKKAAILIGVVVFFIIYFISFRIGINMEKDKSEVPKK
                     VEKEEEDNRSLRTQIKEKKKVYISDKNIENIKIEEDMWDEIKLFFSDFKKVRNTTSSY
                     EAVYEGYSDDGVKFSTDLNFFRVYTVNKEEYYKVPVSSKDAFKKLLDESIYTSFDLLS
                     HYKDWKEVTITHGKEIKKVHRWKFDDLAHKMISKRVVGKVQPEKSKERSDYNFTINIK
                     GDNFDVKVDTMGKDYVKVTSKKNVSYYEVHTSLFDYLKNEIFEIGKK"
     gene            complement(32318..33670)
                     /locus_tag="JAM15_00745"
     CDS             complement(32318..33670)
                     /locus_tag="JAM15_00745"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HAT6796799.1"
                     /translation="MNIHFIGIGGISMSALAEICINKGYQVSGSDSNESYLLDKLRDQ
                     GATIYIGQKKDNISDDVNMVVYTAAVHPDNEELVAAKEKNKLVMNRATFLGQIMREYK
                     NSIAVSGTHGKTSTTSMLSTIFEYADLDPTILVGGNLSMIGGNVKIGNSNHFITEACE
                     YVDSFLNFNPKISIVLNVEEDHLDYFSGIDEIKASFNKFGKLLPPEGYFIINGDDENI
                     DDILYDVKATIIKYGRDSDNDAVIKDIHFDNSGHGIFRIEYEGRDLGEFELSVYGLHN
                     IYNASSAIMAALVSGIDLETIRKNIKIYKGVGRRFETKGYYKNALVVDDYAHHPTELK
                     ATLAAAKKLKKSTLWCIFQPHTYTRTKSLLGEFSEAFYAADKVIITDIYAAREKDPGD
                     IHSKDLVEKLYQNNVDAIYIKEFEDIVKYLRENVKDNDLVITAGAGPIYKVADLLVEK
                     "
     gene            33889..34767
                     /gene="purR"
                     /locus_tag="JAM15_00750"
     CDS             33889..34767
                     /gene="purR"
                     /locus_tag="JAM15_00750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HAT6796800.1"
                     /translation="MKFKRTERIGAIVKILSDNPNKIYTLSYFTNQFNAAKSTISEDL
                     LVVKNVFEKLHLGKVITISGAAGGVKYIPKTSIAENAEFLMELCERICDKSRILSGGF
                     LYLIDLIYDPTIAAKIGKIFASNIEYVDADYVVTMETKGIPMALMTAKAMNLPLVIIR
                     KDIKVSEGPTLSMTYVSGNSSKVESMSLPRKALKPDSKVIIIDDFMRGGGTIKGMVDL
                     MNEFGAEVIGTGVFISTTNPSEKMVKDYISLIQLDVNGDKIVVEPNLKTFKDEYRNED
                     LDEEEDSEFEFEIDED"
     gene            34923..35201
                     /locus_tag="JAM15_00755"
     CDS             34923..35201
                     /locus_tag="JAM15_00755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation protein SpoVG"
                     /protein_id="HAT6796801.1"
                     /translation="MKITDVRVRKLTEEGKMKCIVSITFDNLFVVHDIKVIEGHNGLF
                     IAMPSRKVGEGNFRDIAHPINAEMRQVLEDAVLQAYHEALVQWEVAAE"
     gene            35411..36790
                     /gene="glmU"
                     /locus_tag="JAM15_00760"
     CDS             35411..36790
                     /gene="glmU"
                     /locus_tag="JAM15_00760"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HAT6796802.1"
                     /translation="MNFKAIILAAGKGTRMKSKYPKVIHKVCGKEMVNHIIDVSKKSG
                     VKDTVVILGHEAEVVKEKLAEEIIIAMQTEQLGTGHAVKMAKEYINDEDTIVVLCGDT
                     PLIKEETLKRLFEYHIENKYHATVLTTRVGNPTGYGRIIRDKKGDLLKIVEQKDANSE
                     EKMISEINSGIYCFNGKSLREALDLLNNNNSQGEYYLTDTAKIMRDKGLKVGAFAGST
                     IEELMGVNSRVELSKAEEIMRRRINESHMVNGVTIIDTNSTYIESDVMIGNDTIIYPG
                     VMLQGKTRIGSDCIIGMNSSITNSEIGDGTEIKNSTIIDSKVGENSNVGPYAYLRPKS
                     DLGNNVKIGDFVEVKNAIIEDGSKASHLSYIGDAHVGKNVNIGCGVVFVNYDGKNKFK
                     SVVKDNAFIGSNSNLVAPVVVEEKGYIATGSTITHDVPDGALAIARERQVIKEGWVEK
                     KNQKDDQSK"
     gene            36885..37835
                     /locus_tag="JAM15_00765"
     CDS             36885..37835
                     /locus_tag="JAM15_00765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004167105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate pyrophosphokinase"
                     /protein_id="HAT6796803.1"
                     /translation="MNTSGSEIKIIAGNSSKELAQKIADYIGVSVLDCEVGTFSDGEI
                     CVNMNETVRGCDVFVVQSTNSPVNDNLMELLILIDALKRASAGRITAVIPYYGYARQD
                     RKAKARDPITAKLVANLITAAGADRVLTMDLHAAQIQGYFDIPLDHLLGGTILANYFN
                     EKKIEDLVVVSPDLGSVTRSRKFANTLNGEVPIAIIDKRRPKANVCEVMNLIGDVKGK
                     NVILLDDMIDTAGTIVNAANALKEFGAKDVYACCTHGVLSGPAIERIANSEISELIVL
                     DTIQLPEEKRIDKIKIKTVAPLFGDAIRMIFSNESVSKLF"
     regulatory      38683..38768
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            38930..39451
                     /locus_tag="JAM15_00770"
     CDS             38930..39451
                     /locus_tag="JAM15_00770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HAT6796804.1"
                     /translation="MKLKKNKKGFTLVELLVVIAIIGILAVVAVPALFSNINKAKVAS
                     VESDYSSVKSAALSYYSDTNKIPVTPDGQTGLSVLETYMESLPDKADIGGKYKLIKVG
                     NKLVLQIGTNDEGVTLTEAQSAKLLSDIGKDKIYTGVTGDNFGDQLTNTTKIDNKALY
                     IVLIDNTVMDSTK"
     gene            39603..41279
                     /locus_tag="JAM15_00775"
     CDS             39603..41279
                     /locus_tag="JAM15_00775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HAT6796805.1"
                     /translation="MAKKVRIGDKLVEKGYITEDQLKWALSEQKNSGKRLGEFLVQEG
                     LIDSNLLISVLKELLDIESIFLEGTEIDTLATKMVPENICKRYTVFPFKIDGNKICLA
                     MSDPQDREAVQDVRRMSGKDVEIFISSTEDINKAIGHAYAHSEINKAMTEYNKNRTGG
                     VRETVILEEDVNAAPIVRLVNNILENAVRMEASDIHIEQSENYMRVRFRIDGMLREYM
                     RMNSAPYKAVISRIKIMSDINISEKRIPQDGRIYLKVDNKPIDFRVSTMPTNRDEKIA
                     MRVLDKSNFMVSKEVLGIDEHGSKIYDELINTPYGLILVVGPTGSGKTTTLYSMLNQL
                     NTENRNLLTIEDPIEYELPGVNQSQINEKAGLTFASGLRAFMRQDPDIIMVGEIRDTE
                     TAEIAIRASLTGHLVLSTLHANTAVGAISRLLDMDVESFLITSSVLGVISQRLTRKIC
                     EHCKVSYEADIGEKKALGIDVNESVTIYRGKGCERCNNTGYKGRLGIFEMLEITPEIK
                     ELIDSSANQREILKMARKQGMVSLKEDIVKKVLNGKTTVEEMIRIILMTD"
     gene            41291..42499
                     /locus_tag="JAM15_00780"
     CDS             41291..42499
                     /locus_tag="JAM15_00780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HAT6796806.1"
                     /translation="MKSFKYTVIKEDGKKQTDVIEANDFNEARNLLRKRNLRVIEIKE
                     SKNKNIRLSSRKRKKDLGADQISHFCRQFAIIVSSGINSISGLETLARRSTNITLREE
                     INRIVAEIKVGSTIADSMLSSKSKFPKLLGAMVATGEATGKLDEVLKSMASFYASEHR
                     VKQKLRNAATYPLIVLISSFIMIFIFTTFMVPKMINSITTVGATLPLITRIVMGFGMF
                     MKKFWIIVLLVIILFIYQFKKYLKTSVGRAHKDRVINKIPVLGKGINCMVATRFSRAL
                     YLFVSTGYPLVQGLDYIIDSVNNTMAEKILASAKDGITRGEGLAENLERYTYFDSVLV
                     QMIAIGEQTGELENISRQMAEFYEYESEIYLNRMASMIEPVLIIAVGIIVAILVVSIF
                     MPMLSIYDAM"
     gene            42514..44226
                     /locus_tag="JAM15_00785"
     CDS             42514..44226
                     /locus_tag="JAM15_00785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796807.1"
                     /translation="MNKVYVSYYGDSISIVEGRYKHDKDKFYVKNFNVFSIEDIAQDF
                     SKEKYALLRYALENVKLKSRHVVFCLNTRDVILKPQKLPNMDKKDLDGFMKLEMDEMM
                     ALESDEYVFSYEVSSETPDNSDGDESSLNLIIGAIQKEEVNAIVEIMHEFDLVLDRID
                     TLSTAYLRMLKNLDYNDIMVTNISDNSTIINIYKKDTLFISDNIPIKITAKDMDMQLL
                     NVVEESKGLMNYYSSRNFGKVTDTILILGKRYSNKLIYETFSSAFSSYVSQGLTEIMD
                     ISDMITGDIDEDDINSIVELLGSMIEPKGKRDFENINFLPMDILRKQIKAKQMKNILK
                     IAPIVILILAIPYLCLIFSNNLANKELENVNGEIRNIESAYYQIGNIEKMIQSKSEEI
                     KVYDMLIGKKVKWENLLDDIDKNTPSKVELTSLSTTYQNLGTNNKADNSKSNKTTTDK
                     SSNNETKSSTKSDSNGDKTDNDLNEDKTTNVSEALTGNSETNSNNTDKDDKTPLYDKI
                     PNVINIEGNAKDSSYVGQFLYKLKGLYYFKDVKLHSIKSNAEDSNYTFSMTLYLKEGV
                     LTNE"
     gene            44219..45127
                     /gene="pilO"
                     /locus_tag="JAM15_00790"
     CDS             44219..45127
                     /gene="pilO"
                     /locus_tag="JAM15_00790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 4a pilus biogenesis protein PilO"
                     /protein_id="HAT6796808.1"
                     /translation="MNKDIFKKDIKDIFKMEVSLKGILIKVIILLAILSYGYFGLYPQ
                     YQKYIATKNSVKQATEKLNIYKEKTALMPKYEKQLEEVESELKEKSKNLLYDMQDGLF
                     LIGLDKKMKAYNIDLTSYDVGNVKEYEHFYGISTTISVRGDYRNVKKLMAYLEEQKNV
                     TQILDYTMTSYIEPEKEEEETTNNKDLIKNVNINKDTKIYWVEGENKWHLYKDCPLIK
                     EGEILKNDKLLDRSTNYLCNTCVLRAATEKEAKKEVVAPKAEGVVDATFKFIMYTKEN
                     TTMILDTDNPSSWRPGKYNPFKSSAK"
     gene            45154..45720
                     /locus_tag="JAM15_00795"
     CDS             45154..45720
                     /locus_tag="JAM15_00795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HAT6796809.1"
                     /translation="MSLYKNNEKGLTLLEVIIAVFILTIVLSISYKVFNGITSAVKKQ
                     QIITDAQVNINLINKYLNRDLENCKELTKTGSGNNYEYNIEMPDNVVKYEVSIETKKN
                     TEVYSVTRIQNNTIDTENEVREEIIYNQPLVQNNKEMKETPFKIEKQTGKSIYTVSIY
                     YNESVQESHKNSNLNNKTYTFDVMSRIG"
     gene            45757..46284
                     /locus_tag="JAM15_00800"
     CDS             45757..46284
                     /locus_tag="JAM15_00800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HAT6796810.1"
                     /translation="MSKKNSERGFSLIEVLVAMAIMGIVLFAFFNIINTNNKANTKND
                     TDITSLNYVQSEIENLREKIKSGEFDFDSLDKLEDGTVVYEKLIDKSKKVVYDKVLSE
                     GDVSLYDTPYEKITTIKDEDGNLIDKGNITNKIKTIVEDKSGQIYKIAVTGKSMNDYS
                     SKKEVKIITEIFKDK"
     gene            46305..47843
                     /locus_tag="JAM15_00805"
     CDS             46305..47843
                     /locus_tag="JAM15_00805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796811.1"
                     /translation="MRKWNKFKSERGAALVLVLIVVALLSIVGLIFSNQIANRIKSTK
                     TTNEGIQAKYLAETCVENSIDKAYEKLYDELEKMDNEFKSENQEKSISRSKLRNISDE
                     DFNNQDEENIEVERLGYMNNINFYLNKASSDLEKASMELKKLYDLDMLDYRDIEYVDA
                     NIISHRDSILEICKNYTSGDISKINEYILKEDIDSTTLIEAKLVNNDILLKMFLEENK
                     IENEHLNSAFSHTYKALDNISLAMQNMIEYRHTFHIDEPKVEVSNGIPDSQQYYELIQ
                     NPIINSMEYIWNSKWDTLEKLLEILPNQTQGFNSLRVHLRNNVRKFEKLSDNISSGKK
                     NTAKNFLKYKELLYEISDQCNQLKSMSYEKIPVKYDNMALITTFDYIQNELLAEIKCR
                     LKELKPQEIDKTEGITIKIPFYKADYDMTKEGWPKLKENGSGAELSLMVTGDKDGIKE
                     VEVTDGKKNIIGLGVEENSNSKYKVDTIVNFNLNIDTNVVGNYDIKDKILINHDISSY
                     KKVN"
     gene            47943..49025
                     /locus_tag="JAM15_00810"
     CDS             47943..49025
                     /locus_tag="JAM15_00810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HAT6796812.1"
                     /translation="MYIYDLLEQGIRLNASDIHITVGTNPVARVKGGFVKLSEQILTS
                     EVTMQMAKDIAGESMFTVIEEHGEADFSASLKTGERFRVNAYRQKGNYAIAIRTITAE
                     IPTFEKLGLPESIKSFTEKHKGLVLVTGPTGSGKSTTLASMINIINEKQQKHIITLED
                     PIEYVHHHKQSLVNQREVGTDTESFHSALRAILRQDPDVILIGEMRDPETVSIALTAA
                     ETGHLVFSTLHTVGAAKTIDRIVDMFQPSQQQQIKTQLSTVCEGVVSQQLLPTADGKG
                     RIAAIELMFATPAIKNLIREGKTYQIPNMIQTGVKVGMKTMDQDLMELYKNGKITKDM
                     ALSRCTDQEFMTRMIGGVNYNGYYNR"
     gene            49006..49788
                     /locus_tag="JAM15_00815"
     CDS             49006..49788
                     /locus_tag="JAM15_00815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HAT6796813.1"
                     /translation="MDIIIVNLYVFIVGIVFGSFFNVCIFRIPEGISISRPPSHCMSC
                     NTRLKPIDLIPVLSYLMSGRKCRYCYEKISSRYAIVELITGILFLTVFMLYGISTSTI
                     YYLVLVSLLIIITFIDIDHFIIPDNILIFGAIFSMIFNLLFNEIPVKNSILGVFICGG
                     SVWIIVFLIEFVIKKECMGGGDIKLFAMLGLYMGVKNGLLTALLSVYVGAVYGICVII
                     ISRIKGKEYNSVIPYGPFISIGALITILCGKQLLELYFSMVI"
     gene            49890..50540
                     /locus_tag="JAM15_00820"
     CDS             49890..50540
                     /locus_tag="JAM15_00820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HAT6796814.1"
                     /translation="MEYIIIISLFFAHLINKSLCVFCDREKKNLYNTFFIYIITVVLS
                     VLIYLKFGISVECVQYMVLIPFLIIISIVDYYTIYVYDITIVSGIIVQGIIFLVFFNI
                     AQFDYINHIFGLLIGFIIPYIIAKLTKGLGYGDVGLYSLCCFALGNNYGSYVIVLSFI
                     LAFLFFIILYITKIFKDVDIRKQIPFTPFISLSTILIIFTEYNIFNFYYNLLYKFI"
     gene            50554..51114
                     /locus_tag="JAM15_00825"
     CDS             50554..51114
                     /locus_tag="JAM15_00825"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HAT6796815.1"
                     /translation="MYVVVGLGNPGKKYEKTRHNVGFDVIDILAKEYNISVTKIKHKA
                     LIGEGRVGTEKVLLVKPQTYMNLSGETLIDIYKYYKVDLSNIVVVYDDIDLEVGKIRI
                     RKKGSGGTHNGMKSITKCLGSNDFPRVRVGVSKPEAGQDLADFVLSRFRKEESDNINE
                     ALEKAAYAIDSIIRENIDMSMNKYNG"
     gene            51131..54517
                     /gene="mfd"
                     /locus_tag="JAM15_00830"
     CDS             51131..54517
                     /gene="mfd"
                     /locus_tag="JAM15_00830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HAT6796816.1"
                     /translation="MNDVFLYPLQNSKEYKDIINCIKNTKGSLLVNGLLPVQKPHISY
                     SIFNDLSRQMIFITSSDLEAKKVYEDLSFYMEDKVEYLGFQDIYFYHLDAKDRNEEAK
                     KLKVLLKLANKEKIILVTSIEAVLRKYIPKQVLLDSVSHYKVGDSLDLEKLTEKLVSL
                     GYERVSKIEGFGQFSIRGGIIDVFSLEYTNPIRMELFDDEIDSIRTFDVYSQKSIDKL
                     QQFSITPSREFIYPEKTTDALVKLKKETTKNTDEGTFQNIDYISSKTYFEGVENYIDY
                     IYPEENKSIFTYLADDAIVFINDITRLKERCENYINEFRENYKLNLERGLAIKNQGKL
                     LYHYTDLEYLVKDKSVVLNSLLPKSINNFSIKSIINFESREVPTFNGKVDLLVEELNR
                     LKYNGYKIILATNTLERANKLGKDLLDKGLETTISKDRDIEIKSSQVIIVPAHINSGF
                     QYKSIKFVVITDNEMIGVYKRASKTSNKKVKKGKKIESFLDLSVGDYVVHENSGVGRY
                     TGIEQITVNAIKKDYMKIVYQGGDNLYVPIDQMDKVQKYIGAEVEKVKLNKLGTNEWT
                     KAKAKVKKEIEDMTKDLIELYAKREKIQGYKFSKDTPWQAEFESLFPYQETEDQLKAI
                     EETKKDMESSKVMDRLVCGDVGYGKTEVAIRSIFKACMDQKQVAVLVPTTILAQQHYN
                     TFKERFENYPLRVEVLSRFKTPKQQKQIIEDAKKGLVDILIGTHRIISKDINLPNLGL
                     VVIDEEQRFGVKHKEALKKIKSTVDVLTLSATPIPRTLHMSLSGIRDMSVIEEPPQER
                     HPVITYVTESKESVIQDEIERELSRGGQVFFVYNRVEHIEEMASMIQKLVPDARVAVA
                     HGRMTSKSLENIILGFLNKDYDVLVCTTIIETGMDISNANTMIIYDADKMGLAQLYQL
                     RGRVGRSSRQGYAYLLYEKDKTLSEIAEKRLKAIREFTEFGSGFKIAMRDLEIRGAGN
                     ILGSQQHGHMAVIGYDLYVKMLNDAIKKVKGEPIVEEIDVEIDLSVNAYIPDNYIKDE
                     LIKIEMYKKIASIENKEDMLDIQEELEDRFSDIPKPVQTLLTIAYIKSLCKILKIEKI
                     RQLKDEILLVPITKYRTKQKIGYNIVTELEELLEKMCKVK"
     gene            54548..55543
                     /locus_tag="JAM15_00835"
     CDS             54548..55543
                     /locus_tag="JAM15_00835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAT6796817.1"
                     /translation="MKKVITLVIAMILVVSVTACSSSKGETVATVEGTKISSDEFKKT
                     IALYKDSMEQTYGKDIWDKEVEKGVKYKDKFKDLILDQLITTEVIYSQAKKDNLLPKK
                     EDVEKSFKELKDAMGKDEKYKEQLKKLGIDDEFLRDQQEKDLAMQNYQSNFAKKTKIS
                     DEEMKKYYDTHKDEFKKDEVEASHILLKTVDDNNKPLSDKEKAEAKKKAEEALKEVKS
                     GEDFAKVAKKYSQDTSASDGGKLGFFSRGQMVAEFEDAAFSMKKGEVSDLVETQYGYH
                     IIKVTDRINEQTSFEDAKETIKDQLLKNKYQEQIEKLTKEAKVEKDEKVINKITI"
     gene            55667..56206
                     /gene="spoVT"
                     /locus_tag="JAM15_00840"
     CDS             55667..56206
                     /gene="spoVT"
                     /locus_tag="JAM15_00840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009167752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein T"
                     /protein_id="HAT6796818.1"
                     /translation="MKATGIVRRIDDLGRVVIPKEIRKTLRIREGDPLEIFTAKDGEV
                     ILKKYSPIGELNEFSQEYAETLAEVLGYGVLITDLDSIIAVSKLPKKDYKEKSISDEL
                     EAIISERTVKYSKDKNILPLFKEDQKEYTSQVIMPIISASGDCIGSIVVVSKDKDTIA
                     ESEEKSLKIAANFLGKQVQ"
     gene            56326..57939
                     /locus_tag="JAM15_00845"
     CDS             56326..57939
                     /locus_tag="JAM15_00845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAT6796819.1"
                     /translation="MNNNKNKDSFLKGALILGLAGVIVKIMGGFFRIPLGNMIGSEGM
                     GYYQAAYPVYTLFLTLATAGFPTAVAKLVSEKVAIGNFKGANKIFKVSHTVLFITGII
                     SFCILFFGADYIVTNVMKNPGALYSMKAIAPALLFVPAMSAYRGYFQGRQDMTKIAVS
                     QVAEQFFRVVLGLTLAYLLMKSLGQTFGAAGAISGATIGSIASMLYLVFAYMLGRKER
                     RAEIDASQRFKDERVSYIFKKLLTVAIPITIGASVMPLVNMIDNVIVIRRLMEAGFTY
                     KVANSMFGQLTGMAMATINLPAVITTAMSMSLVPAISKAYALGNKSKARKDTKSAVKV
                     TLLIVLPCAFGMASLAIPIMGLLFPHEPSSVGTILFTLTPCVLFLGLIQTLTGIIQGM
                     GKPIVPVIALCVGMLCKIVISYTLTGIPDINVLGSAFGTVTAYFVAAMINLLYVKKHM
                     NVNFSKKEFIIKPFITVMTMFIMVKLSYGALVGFLGNSISTIIAICVGGIVYVVVILG
                     IGGIKKEEILTMPKGDKLYKLLKKVKLIR"
     gene            58046..59494
                     /gene="mazG"
                     /locus_tag="JAM15_00850"
     CDS             58046..59494
                     /gene="mazG"
                     /locus_tag="JAM15_00850"
                     /EC_number="3.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="HAT6796820.1"
                     /translation="MGKISIVGLGPGDYSLISQGVLESLINSPKVFFRTEKHPIIDKL
                     KETIQYTSLDYFYEKEENFDNVYLKISEFIIEESAKGDLVYAVPGHPRVAEKTVSIIE
                     RLANEKHIAVEILPSMSFVDAMFNYLAIDPSEGFKLVDAFEIENSYIDLDTSMIITQV
                     YDKFIASNVKLKLMEHYDYNQEVCIVNGAGVKDLESKKFIKLCELDRNENFFDYLTSL
                     YIPKSSKKMYNTVHDLEIIVNTLRSPSGCEWDKKQTHQSLKNSVIEEAYELCNAIDNN
                     DIDEMVEELGDVLLQVIFHCQIGNEEGYFDLKEVVNGICKKLIHRHPHIFSGAKLDMS
                     KFEKTWEELKKEEKGESTITDGLRRIPKHLPALMKASKVQHKAALVGFDWDNVEDVFK
                     KIEEEYQELLDEHRVGNIKYIKEELGDLLFSIVNLARFLDIDSGEALNCTTEKFINRF
                     DFIEKSAMNLNKKLEDMTLEEMDEFWNQAKKQ"
     gene            59583..59861
                     /locus_tag="JAM15_00855"
     CDS             59583..59861
                     /locus_tag="JAM15_00855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HAT6796821.1"
                     /translation="MNKAELVSKMAEKSGLTKKEAEAALNAFMSSVQDALVNNEKVQL
                     VGFGTFETRERAARQGRNPRDPEQVIDIPASKAPVFKAGKGLKDIING"
     gene            59933..60175
                     /locus_tag="JAM15_00860"
     CDS             59933..60175
                     /locus_tag="JAM15_00860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HAT6796822.1"
                     /translation="MRLDKFLKVSRIIKRRTVAKDACDKGIVTINGKVAKSSSEVNIG
                     DTLEIQFGEKKMKFKINEVKEHVLKNDAKEMYEILE"
     gene            60237..60491
                     /locus_tag="JAM15_00865"
     CDS             60237..60491
                     /locus_tag="JAM15_00865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YabP"
                     /protein_id="HAT6796823.1"
                     /translation="MEQNITLKDRSKLVISGVEHIYSFNDKRVELKTSVGEMVIEGEN
                     LDMSKLSIDENIISIDGTINSMVYAKPKKPQESFLKKVFR"
     gene            60492..61025
                     /locus_tag="JAM15_00870"
     CDS             60492..61025
                     /locus_tag="JAM15_00870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796824.1"
                     /translation="MIPFTQDVSIFYATIYGGILIGVLFDFYRGLRGNFKFINYFAII
                     FDVLFWFLATVIIFVTINLTEFFDLRYYHFVALFIGFILYYNTISKIVLSIINKIIRF
                     VRNSFKKVTHYIVSFLNNLYYVIIYSLHLLFDIIFYIPNIFIATRKSIKRKSNKKLKN
                     KKKSKPKKKKNKTKKRV"
     gene            61031..61315
                     /locus_tag="JAM15_00875"
     CDS             61031..61315
                     /locus_tag="JAM15_00875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HAT6796825.1"
                     /translation="MNLRKKFSGQIIVISLFLGISIFSMMTGFVFEYTKAKEYKKEIA
                     SLNKQLKKTEIQINSLKKDEKSYEGDLEDIARKRLNMVKPNETVYVDINR"
     gene            61428..62348
                     /locus_tag="JAM15_00880"
     CDS             61428..62348
                     /locus_tag="JAM15_00880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ppx/GppA family phosphatase"
                     /protein_id="HAT6796826.1"
                     /translation="MKVGAIDIGTNSMRLLIADYRDGNFINRKKFVNTTRIGYGVDSK
                     GYIKEDAIKRNIKALKEFSDKCNDEKCEKIYCMGTSALRDSKNGDYFVKLAKEETGID
                     VDIVTGIEESNLGFKGVLEGIQGDDTIIVIDIGGGSTEFIVGDSEGIKFNKSENVGAL
                     RMTERFLKHDIIEDEEFEAMSSFIYDEIDKTLNHIKDRGLKTLIGIGGTITSLSAMNQ
                     ELEIYSMEKIHNSKIHKKEIEEILQKLIKMTLSDKKNLKGLQEKRADIITAGVKILNI
                     IMEKLEIEEITVSEYDNLEGLICQKSKKMY"
     gene            62438..64810
                     /gene="spoIIE"
                     /locus_tag="JAM15_00885"
     CDS             62438..64810
                     /gene="spoIIE"
                     /locus_tag="JAM15_00885"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein E"
                     /protein_id="HAT6796827.1"
                     /translation="MQRSVAVVKNKTVKPNVIKLISGYIDFTTAAFAVMGFLLSRSII
                     VDSVAPLGIAFFICASKIDKYKIPVFISTLLGILLSSNDFGNVAKYAVCLTIFMAMNK
                     KLKLSDSIAKVAFIGAIILLPISMGQAFFSNRYVYGLLIAGVEAIIMFISIYVFSYGI
                     GLMANVNNRMSVRTEEAISISLLLTFSIMGIGDISLFGISIRTILSTVLILLTSIVGG
                     ATMGASSGVIIGVASILNNMTSAVYMGIYSFSGLISGAFNKINKYFCILGYILSWTII
                     YLYTSGITSNMMQLRDILLGCLIVLVLPERLFNKIEKLIKSNVASNEIVYDYIMRSKN
                     LTNSRLNSIYKTYDDLADTFDKIREKDKVLDQRDIANVIDMIHNDECKSCSMRRMCWE
                     SRFNHTYTMIYNILEKIEEKGELSLNDIPKNFRKECMKPESIVKISNHYYKMFVLDYD
                     WSVKFSESRKLIANQIRSISKSIKSLSQDLEGDIMLDIEKEKNIYEQLERYDITVDKV
                     SYLTKSNNEFEISIEKKTCHDGCMCEDKIVNIISDLVGENMSVRKIGCHCLGGKCKAT
                     FVKSQKYKAVTEVSAMSRDGHILCGDNYTYMEINDGKYMMAISDGMGKGKKAYEESSA
                     TIDILEKMIDAKIKDEIVIDTINNMLLLKSSEEMFSTLDLGILDLKRGCLETIKMGAC
                     STYIKREDGEVDLISSSSLPVGILSDVKIDRKNVKVKEGDYVIMVSDGIVDAGRNNNL
                     GDNWLIYFLKNIETTNPKEISNLILDRALELQALQIEDDMTVLVTKICTK"
     gene            65161..67053
                     /gene="pepF"
                     /locus_tag="JAM15_00890"
     CDS             65161..67053
                     /gene="pepF"
                     /locus_tag="JAM15_00890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HAT6796828.1"
                     /translation="MNRKLCKAIIPLFISIFCMLIISIKADQGYQKNNDRAIAVMNNN
                     DIEDDAEKKQEVDYEKTCWNLQSLFKSDDQWKKELKSFDKDTKELKNYIGKVTKSPTH
                     LSFALNIKEKLDIRLNKLSAYVKLKQDTNKNSYKYLDMSDSMSKSYGNYMGICSDLEL
                     EILKLSNKDYKKIISNKNINRKYGAYLRDIRRNKVHYLDDKSEDILSKVSSISSLPSQ
                     VYELFRNMDRKTNLTPAQYASELESVDRENRKKAYQDELITYNDNINTIAGLITGQVK
                     KNIFYSQERGYESSLEMYLESDNVDEKVYNNLIRTVNSNMDSLHKYIDLRKKVLKLDK
                     VHSYDMFVPMVKAVDNNINYEKAQSIVYSALSPLGKEYNDVVYKAFNEKWIDVYSHEN
                     KVSGGYCLSVYENHPYILLNYNNSLGSVSTLSHELGHAVYEYLSSKNQNYFNSNPSIF
                     THEVASTTNEALLYEMLIKEAKGNDEKAYYITQYLDLIKDTLYTQTMYAEFEKTIHEL
                     VEKGKSVNALVLNDVWGQLLKKYYGQSYELDQLSKVGWARIPHFYNSFYVYKYATGCS
                     AGVSFAQDILKNGSDNYMSFLKKGSSDYPINLLKSSGINLTNTKPIENTIKKFDSLVA
                     ELEKLL"
     gene            67167..68132
                     /gene="galU"
                     /locus_tag="JAM15_00895"
     CDS             67167..68132
                     /gene="galU"
                     /locus_tag="JAM15_00895"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HAT6796829.1"
                     /translation="MQVKVKKAVIPAAGLGTRFLPATKAQPKEMLPIVDKPTLQYIIE
                     EAVASGIEEILIITGRNKKSIEDHFDKSVELELDLEKKGKKELLEVVQNISNMINIHY
                     IRQKEPKGLGDAIYCARHFIGDEPFAVMLGDDIVDNDVPCLKQLTDAYEEYRTTILGV
                     QKVNQEDTNKYGIIEAKNIEGRVYKVKDMVEKPESGKAPSNIAILGRYIITPEIFDIL
                     KDLPPGKGGEVQLTDALKILSKKEAMYAYNFEGKRYDVGDKLGFLEATVDFALKKEDL
                     KEDFIKYLKHVCSEFDKNNNVLYNNTDEKIDLIEVNEARELEIQK"
     gene            68632..70236
                     /locus_tag="JAM15_00900"
     CDS             68632..70236
                     /locus_tag="JAM15_00900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HAT6796830.1"
                     /translation="MRRIFLILDDKVLEGLGSKTLVELREIAKELKIKSITTYKKNEL
                     IEIINSKSKNEEKVNEETKEKNEDIKEDIKNRKENIERESIEKEVEYKSPTKSYNKKE
                     IDTQNISQNQENRNQRNDYNKTTSVNDSNKSSNISNRMVRNNNKNYYMPKQVDESKIV
                     DEFNTSKEDEVVGVLEILPDGFGFLRGSNYLSTEGDVYVSPSQIRRFNMKTGDKIKGI
                     TRHPKSGEKFRALLYVQKINDENPDTAIQRNAFETLTPIFPEERLTLETNRNEIATRI
                     IDLISPIGKGQRGLIVAPPKAGKTVLLKSVANSIAKNHPNVELIVLLIDERPEEVTDM
                     KESIEGDVIYSTFDQVSSHHVKVAEMVLNRAQRLVEHGKDVVILLDSITRLARAYNLT
                     ISPTGRTLSGGIDPGALHGPKKFFGAARNIRQGGSLTILGTALVETGSRMDDVIFEEF
                     KGTGNMELHLDRKLAEKRIFPAIDIYKSGTRRDDLLLDDEEKTALWKLRREMSNNSVM
                     EITDKVIELIKRTKDNKEFVKSIKNL"
     gene            70389..70589
                     /gene="rpmE"
                     /locus_tag="JAM15_00905"
     CDS             70389..70589
                     /gene="rpmE"
                     /locus_tag="JAM15_00905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002844141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HAT6796831.1"
                     /translation="MQKEIQPKYNPVEVRCACGNTFVAGSTKDEIKVEICSECHPFYT
                     GKQKNIEKGGRIDKFKKRFKMD"
     gene            70734..71627
                     /locus_tag="JAM15_00910"
     CDS             70734..71627
                     /locus_tag="JAM15_00910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1385 domain-containing protein"
                     /protein_id="HAT6796832.1"
                     /translation="MAKQAVGGQAVIEGVMMQSKDKRAVAVRKSDGEIALKEDRIKSW
                     VRDKNIDKIPFVRGSFVMIDTMIQGIKSLNFSSEFFMEEAEEDKFDLFIKKIFKDKAN
                     DIIIIFSLVIAMLLSAGLFIFIPTLVGGAFSKVMPNDFMLNLIEGIIRIVILFAYIVL
                     ISRSKDIERVFQYHGAEHKSIYCYENDLELTVENARKFKRLHPRCGTNFLFIVMAVSI
                     ILFAFFGWPNPILRIFMRIICVPIVAGLSYEVIRVLGKYDNGFTKIIAYPGMMLQYFT
                     TKEPDDEQLEVALEALKAVVD"
     gene            71645..72493
                     /gene="prmC"
                     /locus_tag="JAM15_00915"
     CDS             71645..72493
                     /gene="prmC"
                     /locus_tag="JAM15_00915"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HAT6796833.1"
                     /translation="MTIKDIIIKYSDKLKDISDTPRLDTELLLQKTLGVDRLYIHLNL
                     SKELTEEQKTKFIGFAEERLNGRPIAYIVENREFMGLDFFVKEGVLIPRPDTETLVEE
                     IIEICREKKDVSILDIGTGSGAITISLAKYIENSKIMSFDISETALEIAKKNAIINEV
                     GEKIKYINSDLFTAISDSNIKFDIIVSNPPYIKKQDIETLHKQVKDYEPYNALEGGED
                     GLDFYRRITEQGKKYLNKCGILAYEVGHNQAEDVINIMKSNGYKKIYTKKDIQGIDRV
                     VIGYNI"
     gene            72537..73601
                     /gene="prfA"
                     /locus_tag="JAM15_00920"
     CDS             72537..73601
                     /gene="prfA"
                     /locus_tag="JAM15_00920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002845154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HAT6796834.1"
                     /translation="MLKKLEVLEDTYKDLSEKIGDPDVINDQKVWQKYIKEHADLEPI
                     VMKYREYKSVLDRIKESKEILQEESDEELRELAKMELAEMEEKVAPLEEEIKILLLPK
                     DPNDDKNVIVEIRGGAGGDEAALFAGDLFRMYSRYAERRRWKIELLSASDTGVGGYKE
                     VSFMIKGKGAYSRLKYESGVHRVQRIPSTESGGRIHTSTSTVAVLPEVEDVEVEINPN
                     DLRIDVFRSSGNGGQSVNTTDSAVRVTHIPTGEVVSCQDGKSQLKNKEQALKILKARL
                     YDKALAEQHKDIAAERKSQVGTGDRSERIRTYNFPQGRISDHRINLTLYKLDAFLDGD
                     IDEMIDALITVDQTEKMTAI"
     gene            73730..74410
                     /locus_tag="JAM15_00925"
     CDS             73730..74410
                     /locus_tag="JAM15_00925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HAT6796835.1"
                     /translation="MILKVTIIGLLAGVIGTGLGGVISAIFKREVDKYLSFFMGLSGG
                     IMLAVVVFDLMKESMDKMGIINTVIFTFVGALITMYIKTKLDVSGNMASGYLIFISIL
                     LHNLPEGLAIGSSFMSTESLGITLAIVIGLHNIPEGLAMALGLVCNKMKLSKVILFTV
                     IAGLPMGLGSFLGVYFGGVFTSLIGVFLATAGGTMMYVVLEEIFPHSKSVYCIIGFLL
                     GTMIVNYI"
     gene            74439..75479
                     /locus_tag="JAM15_00930"
     CDS             74439..75479
                     /locus_tag="JAM15_00930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HAT6796836.1"
                     /translation="MKTIISNIDINNIDYEEIKIQAKLLREGKTVIFPTETVYGLGAN
                     ALDENAVKKIYEAKGRPSDNPLIVHIYEKEEVYDLAKDISDKAKLVIEKLWPGPITII
                     LNKKDIIPYKTSGGLDTVAIRMPSNVIARAIIKEAGIPIAAPSANISGRPSPTKAKHV
                     YEEMNGRVDGIVLGGDSNFGLESTVLDLTEETPMILRPGSITKEVLEELLGEVKLDPS
                     LSKKEDNQKAKAPGMKYKHYSPNADVYIISGKRENVATKINDMIKSNRDKGLKTGVMC
                     ISRNREFYDGEVIDLGNSLEEVASNLFDALIEMDKKGVDVIYSEEFPKTGVGQAIMNR
                     LLKSAGYKVIKA"
     gene            75496..75945
                     /locus_tag="JAM15_00935"
     CDS             75496..75945
                     /locus_tag="JAM15_00935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight protein arginine
                     phosphatase"
                     /protein_id="HAT6796837.1"
                     /translation="MNILIVCTGNTCRSPMAEAILRKAIKESGRSIEEYSISSAGIST
                     ANGMGASENSIEVLKEIGIDLSNHRSKVITKKLIDESDIILTMTKSHKEILVQAVPKC
                     KEKVYTFKGFANKNEEDISDPFGGNLDIYRSTMREIMYSVNEIVKKI"
     gene            75962..76414
                     /gene="rpiB"
                     /locus_tag="JAM15_00940"
     CDS             75962..76414
                     /gene="rpiB"
                     /locus_tag="JAM15_00940"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HAT6796838.1"
                     /translation="MKIGLGCDHGGYNLKKEIISYLESKGIECVDYGTNNATDSVDYP
                     VYGEIVANSVINKEVDYGILCCGTGIGISLAANKVPGIRCAVVSDVFSAKMSKAHNDA
                     NMLSLGERVLGKGLALEIVEAWINTDFEGDRHARRVNMIKSIEEKHNK"
     gene            76450..77079
                     /gene="upp"
                     /locus_tag="JAM15_00945"
     CDS             76450..77079
                     /gene="upp"
                     /locus_tag="JAM15_00945"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002845151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HAT6796839.1"
                     /translation="MSKVVETNHPLIQHKLTLMRDKNTGSKDFRELLTEIAMLMGYEI
                     TKDIPLKDVEIETPIQKTSSKVVAGKKLAIIPILRAGLGMVDGLVSLMPAAKVGHVGL
                     YRDPETLKPVEYYCKLPQDIGERDIIVVDPMLATGGSAVAAIDLLKSKGAKSIKLANL
                     VAAPEGIAEVQKYHDDVDIYVASVDERLNEHGYIIPGLGDAGDRLFGTK"
     gene            77379..78194
                     /locus_tag="JAM15_00950"
     CDS             77379..78194
                     /locus_tag="JAM15_00950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF2563 family selenium-dependent molybdenum
                     hydroxylase system protein"
                     /protein_id="HAT6796840.1"
                     /translation="MKNCIAVRGAGDLATAVIHKLHNSGFKVVALEIEEPLAIRRQIS
                     FCEAVYEKKVTVEGVECIFCNTEKEIEEVLSQHKVALIIDPKGEKLSKLNPIVLVDGI
                     LAKKNLGTTKDMAPLTIALGPGFCAGEDVDVVIETMRGHNLGRIITNGRAEKNTGVPG
                     AIKGFSKERVMHSQYDGIMENVCKIGDIVEKGDLLCYINNYEKKHEVRATISGVLRGL
                     LKDGAKVNKNLKILDIDPRKEEVKNAFTISDKARCIAGGVLEAILNNGIYPQN"
     gene            78420..78857
                     /locus_tag="JAM15_00955"
     CDS             78420..78857
                     /locus_tag="JAM15_00955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003512977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dCMP deaminase"
                     /protein_id="HAT6796841.1"
                     /translation="MRPSWDEYFMEIAEVVKKRSTCIRRQVGAVIVRDKQILTTGYNG
                     SPRNLEHCENIGCKRQELNIPSGERHELCRALHAEQNAIIQAAHNGISVDGATLYVTT
                     RPCVLCAKMCINAGILKIVYEGDYPDDMSTELLKEAGIELIKF"
     gene            79042..79269
                     /locus_tag="JAM15_00960"
     CDS             79042..79269
                     /locus_tag="JAM15_00960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AtpZ/AtpI family protein"
                     /protein_id="HAT6796842.1"
                     /translation="MSKRNTHTEIAKLFSLISQIGLMIVISILGCTFLGKFLDSKLNT
                     TPVLTIIFLLLGVGGAFSGVYKTLIVYTRRK"
     gene            79274..79660
                     /locus_tag="JAM15_00965"
     CDS             79274..79660
                     /locus_tag="JAM15_00965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase subunit I"
                     /protein_id="HAT6796843.1"
                     /translation="MDIKLLNQVRSVTKGIVIFDVVLIVLMLITSTLSKPVLLGLIFG
                     SIIAMLNFRLLAISLEKSVTFPAGKAQAYASAQYAVRLFIMAVVLIASATVPHLNIIG
                     TALGLLSTKFVILSKNFINKLKRKEA"
     gene            79663..80367
                     /gene="atpB"
                     /locus_tag="JAM15_00970"
     CDS             79663..80367
                     /gene="atpB"
                     /locus_tag="JAM15_00970"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HAT6796844.1"
                     /translation="MNQAHYYLIGNFKISETILVSWGIMAFLAIASYFLTRNLKKVPT
                     SKVQIFLEFAVGGLAKMVTDVMGKNTVKRMPYMIPYIGSLFLFFACSNLSPLLGLRSP
                     TTDLDTTAAWAMITFFMIYFAGVKFKGLSYFKELAQPLAIMLPINIIGELARPISLSF
                     RPFGNILGGTIIMGLFYQLLGFISSLIPGLSIPIGEILIPVPLHLYFDLFAGLLQAYI
                     FIMLTMVFISSAGELD"
     gene            80436..80696
                     /gene="atpE"
                     /locus_tag="JAM15_00975"
     CDS             80436..80696
                     /gene="atpE"
                     /locus_tag="JAM15_00975"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HAT6796845.1"
                     /translation="METAIVAAASAIGAGIAVATGIGAGIGQGIAAAKAAEAVGNQPE
                     AKGDITSTLLLGVAIAESSAIYGLVISIILLFVNPFFKYLGM"
     gene            80819..81316
                     /gene="atpF"
                     /locus_tag="JAM15_00980"
     CDS             80819..81316
                     /gene="atpF"
                     /locus_tag="JAM15_00980"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HAT6796846.1"
                     /translation="MEKALVGITWEFVFQIVNTFIIFLLLRKLLFKPVLNIIESREND
                     IKSDLAEGEKAKNEGLALKKEYESKINFAKDEGQEIIKQATIRAEQKSDDIVNTAKKD
                     ALDIKEKANKDIEQERQKVINEIKNDISNIALLAASKVIEKDLDKSKHEELIENFIKE
                     VGEAK"
     gene            81313..81858
                     /locus_tag="JAM15_00985"
     CDS             81313..81858
                     /locus_tag="JAM15_00985"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HAT6796847.1"
                     /translation="MINVIANRYAEALFQLGEEENSTDVLFKELEKVVDMMTKVSKDF
                     YKVLKSPLVSKSEKKNLVEIIFSKEVSSNIKNFLKVLVDKDRISYLEDIELAYKELLN
                     KKNNVIDGVAISAIPMSETDIKELEVKLSNKYNKNVTIENVVDKTILGGVLVRIGNEQ
                     IDGTVKTRLDKMKEKLSEVIS"
     gene            81875..83377
                     /locus_tag="JAM15_00990"
     CDS             81875..83377
                     /locus_tag="JAM15_00990"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HAT6796848.1"
                     /translation="MNLKPEEISSIIKQQIKNYENKVELTDTGSVLTVGDGIASVYGL
                     EKAMSGELLEFPGEIYGMALNLEEEVVGAVILGDDSEIKEGDIVKRTGRIVEVPVGEA
                     LIGRVVNSLGQPIDGKGPIAYTKTRPVESEAPGIIDRRSVYEPLQTGIKSIDSMIPIG
                     RGQRELIIGDRQTGKTSIVIDTILNQKGKDVICIYVAIGQKRSTIAQLVSSLEKGGAL
                     DYTIVVSATASESAPLQYIAPYAGAAMGEEFMYNGKHVLIVYDDLSKQAVAYREMSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDELGGGSMTALPIIETQAGDVSAYIPTNV
                     ISITDGQIYLQPELFYSGVRPAVDPGISVSRVGGSAQIKAMKKVAGTLKLAYSQYREL
                     AAFSQFGSDLDEDTKKRLAQGERIVEILKQGEHQPIKVENQVMIIYAVINNHLEDIPI
                     DNIARFESELYAFVDNNYPEISRKILGGEDFTHDLTDAINEFKEKFVVEV"
     gene            83405..84283
                     /gene="atpG"
                     /locus_tag="JAM15_00995"
     CDS             83405..84283
                     /gene="atpG"
                     /locus_tag="JAM15_00995"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit gamma"
                     /protein_id="HAT6796849.1"
                     /translation="MAGAGIKAIKTRMGTVESTKQITKAMELVASSKLRKAKEKAEDS
                     REYFNTLYNTVKDIAQTTRGIRNEFLKEREVKNKCYVVVAGDRGLAGGYNSNVLKESV
                     SHMKGKKETVITVGKKAHEFFSKRNYNIAKDINSVEACGYEDATEISQTIIDLYKKGE
                     VDEVYIAYTKFKSALSQEVEILKLLPLVFEKDTDEQGMAVKEEKQNRSKVQYIPSAEA
                     VLSYIVPQFISGTVYGGILESFASEQGARRTAMESATDNANEMLSNLELSYNRARQSA
                     VTQEITEIVGGVEALK"
     gene            84296..85690
                     /gene="atpD"
                     /locus_tag="JAM15_01000"
     CDS             84296..85690
                     /gene="atpD"
                     /locus_tag="JAM15_01000"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002845162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HAT6796850.1"
                     /translation="MANVGKVVQIVGAVLDVKFDSEQSLPNLLNALVIKLGDKEIVAE
                     VAQHIGDDTVRCIAMSATDGLVRGMEVVDTGGPISVPVGDETLGRIFNVLGKPVDGKP
                     APKSAPKLPIHRPAPAYDELETTAEILETGIKVVDLLAPYLKGGKIGLFGGAGVGKTV
                     LIQELINNIAKQHGGISVFSGVGERTREGNDLYGEMSESGVINKTALVFGQMNEPPGA
                     RMRVALTGLTMAEHFRDEQGQDVLLFVDNIFRFTQAGSEVSALLGRMPSAVGYQPTLA
                     TEMGALQERITSTKKGSITSVQAVYVPADDLTDPAPATTFSHLDAKTVLSRQISSLGI
                     YPAVDPLESTSRILDPSIVGKEHYEVARGVQSILQRYKELQDIIAILGMDELSDEDKL
                     IVARARKIQRFLSQSFTVAEQFTGNPGQYVPVKETVRGFKEILEGKHDDLPESAFLFV
                     GTIEDAVRKAKGSM"
     gene            85693..85953
                     /gene="atpC"
                     /locus_tag="JAM15_01005"
     CDS             85693..85953
                     /gene="atpC"
                     /locus_tag="JAM15_01005"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit epsilon"
                     /protein_id="HAT6796851.1"
                     /translation="MASEFSLKVVTPSNTFYDGDVEMIVVRTTKGDKGVLKGHIPFVS
                     GIPVGTLKIKKEGSFKEAKIAEGFINVTQDKTVILTESAEWI"
     gene            86415..86795
                     /locus_tag="JAM15_01010"
     CDS             86415..86795
                     /locus_tag="JAM15_01010"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HAT6796852.1"
                     /translation="MNIFDIGVDIIEIDRIRKAVDKNNRFLEKIFTDREIEYFNSKNF
                     KAESIAGNFAAKEAISKSIGTGIRLFNFKDIEVLRNEMGKPIVKTYNNLAKMCIDYNV
                     LEIKVSISHSKDYAIANAITIIKD"
     gene            86810..87271
                     /locus_tag="JAM15_01015"
     CDS             86810..87271
                     /locus_tag="JAM15_01015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAT6796853.1"
                     /translation="MMDKTAKEIMTTDVIVAKQDDSIADVANMLIAEKIGGLPVVDSE
                     NRVVGIISETDILKKEKYIEAPLYINLLQGLIFLDDLKKVEKDIKQVAAYKVGELMSK
                     DIIKVHEDDKFDDVANVMIKKSINRVPVVDDDNKLKGIICRYDIIKALYNE"
     gene            87292..87882
                     /locus_tag="JAM15_01020"
     CDS             87292..87882
                     /locus_tag="JAM15_01020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796854.1"
                     /translation="MRKKWTIVCIMFLALVIIVIGCQKRQSTKEEVYKDFQKQISDMN
                     YYSCKAEVEVVGNKSPHNYVLIHTYKKTDNYKLEVISPKHLKGKSIEYQGDKILVKNP
                     KISDVVELPNTGKNNQYLFVGDFIKNYLQNEEMKVKLSKGHLVLETFIPGDNKYFNKQ
                     VLYVNADTKNPEKMEVLDKEGVPRFTVKYKDFEYRN"
     gene            87897..89054
                     /gene="alr"
                     /locus_tag="JAM15_01025"
     CDS             87897..89054
                     /gene="alr"
                     /locus_tag="JAM15_01025"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HAT6796855.1"
                     /translation="MQKITVPTWAEINLDNLRFNLNNIKNLLEEDIKICGVIKADAYG
                     HGAVEVAKLLEKEKVDYLAVARTAEGIELRQNGITLPILNLGYTPDEAFEDSIKNKIT
                     MTVYSLETAQKINEIAKSLGEKACVHVKIDSGMTRIGFQPNEESVQEIIELNKLEYID
                     LEGMFTHFATADEVSKEYTYKQANNYKFMSDKLDEAGVKIAIKHVSNSAAIMDCPDLR
                     LNMVRAGIILYGHYPSDDVFKDRLELRPAMKLKSKIGHIKQVEPGVGISYGLKYTTTG
                     KETIATVPIGYADGFTRIQKNPKVLIKGEVFDVVGRICMDQIMVRIDKDIDIKVGDEV
                     ILFGEGEVTAERIAKDLGTINYEVLCMISRRVDRVYMENNELVQINSYLLK"
     gene            89087..89374
                     /locus_tag="JAM15_01030"
     CDS             89087..89374
                     /locus_tag="JAM15_01030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HAT6796856.1"
                     /translation="MYDKSKEKIEVTLPDSLISEVDSIVQMENSNREDFAKAAFQFYI
                     TQKKKIHIKESMKTGYREMGQINLSLAELGMTVEEVSSDDKNEGKIAQGEY"
     gene            89343..89726
                     /locus_tag="JAM15_01035"
     CDS             89343..89726
                     /locus_tag="JAM15_01035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAT6796857.1"
                     /translation="MKGRLPKVSTNCEIKRGDLYYADLSPVVGSEQGGVRPVLIIQND
                     VGNKYSPTVIVSAITSQINKAKLPTHVEISSNEYGLNKDSVILLEQIRTIDKKRLREK
                     IGCLDENMMIKVDDGLQISLGLFTF"
     gene            89897..90724
                     /locus_tag="JAM15_01040"
     CDS             89897..90724
                     /locus_tag="JAM15_01040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HAT6796858.1"
                     /translation="MRDHKGLNEIARIIRRDIVSMIHRAKSGHPGGSLSVVEILTALY
                     FDEMNVDSSNPKMEDRDRFVLSKGHAAPALYATLAEKGYFDKEELNGLRKIGRMLQGH
                     PDMKGTPGVEISTGSLGQGFSVACGMAMASKLDNAPWNVYTLLGDGEVQEGIVWEAAM
                     SAAHYKLDNLIAFLDNNGLQIDGDIESVMSLGSIVDKFKAFGWNVIEIDGHDFDQIFA
                     ALDIAKSTVKKPTMIVAKTIKGKGISFMENQAGWHGTAPSDEELEKALLELGGADNE"
     gene            90717..91658
                     /locus_tag="JAM15_01045"
     CDS             90717..91658
                     /locus_tag="JAM15_01045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HAT6796859.1"
                     /translation="MSKMATREAYGKALVKLGQINDNVVVLDADLSKSTKTHDFYKSF
                     PDRFFNMGIAEQNLIGAACGLSTAGKIPFASTFAMFATGRAFEIIRNSVCYPKLNVKI
                     CATHAGLTVGEDGASHESVEDIAIMRAIPNMTVLVPADGVETEKIIFEIAKYNGPVYV
                     RLGRSSVPVLFDEDYKFEIGKGTVLREGKDVSIIACGIMVNEALLAQEKLQEEGINAR
                     VINMSSIKPIDKDLILESAKETNAIVTVEEHSIIGGLGSAVSEVVGESCPTIVKKVGI
                     KDTFGESGTPNELLKKYELTCDDIIKTVKEAIIAKRM"
     gene            92082..93176
                     /locus_tag="JAM15_01050"
     CDS             92082..93176
                     /locus_tag="JAM15_01050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796860.1"
                     /translation="MSEKVNVKTVISFAGAYVATVIGSGFATGQEIMQFFSFYGFAGI
                     IGGIISMVLFSWMGASVMSKGKELQLKEPIKIYRVYCGKYLGIFFEWFGPLFLFGVFV
                     VMISGAGATLTEYYGLNPFVGRVGMAVVALLTVSLGLDKLSKILGGIGPIIIIFTLLV
                     GGISLAKNIGNIGEAAQVLSTVKIAKPVPNAYLSGVIYTTYNTIVVMAFLTGLGASAA
                     NKKEAICGGILGGVALMAAAIMMHLAILSDIGNLYSKAIPSLFLADKISPVIGVLFSI
                     ILILGIYTTAVPLLWSVTNRFVDDKHPKFKLITLIAAILGLIGGFLPFDKLVGILYPY
                     TGYMGVIILVCVLYRQITKTSGYQEGISDK"
     gene            93402..93818
                     /locus_tag="JAM15_01055"
     CDS             93402..93818
                     /locus_tag="JAM15_01055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796861.1"
                     /translation="MNVKFNIKGIIYGVIALVFVIGGFIFIPSMFVEKSKPIDYTVLQ
                     RNSIPEKILDVMDKYTNEERALAAKIDNKIYIIVTRGNNKYGIEMDKIESVVEEGKDV
                     LRVKIKYKDKEDSFPYIVVETNMSELPDRIELNATK"
     gene            complement(94000..94569)
                     /locus_tag="JAM15_01060"
     CDS             complement(94000..94569)
                     /locus_tag="JAM15_01060"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HAT6796862.1"
                     /translation="MKKEFRKKVIESRKNKSANFVLSNSNLITEKLLQMEDIRNATNI
                     MLYLNFNNEVQTDNLIKKLLSLKKIVSSPITIKENHTLIPTQITDLKEGLRIGAYGIR
                     EPNEKSPTIDIKALDVVIVPAVAYDIHCYRLGYGGGFYDRFLENLRKDAITIGIAFDF
                     QIFDSIPKETHDAQLDYIVTETRIITPNN"
     gene            94723..95880
                     /locus_tag="JAM15_01065"
     CDS             94723..95880
                     /locus_tag="JAM15_01065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HAT6796863.1"
                     /translation="MYLVISKKKAIFLGVILVIITAMVTSAFQLTLGNKVVISKELYE
                     DYKKYDKLLGLESIIKQDFYKKVSDTDLVNGAAKGLFLGTNDKYSGYYTKDEMENLIN
                     DSEGSYVGVGMYIGASKDGGLVVVPMKDSPAEKAGVKSGDKLVKVNGKSVSYKNSDEA
                     VRMMKGKKGKTVELTILREDKQFNFKVKTDQIIEKSIESKVIDNDLGYIEITQFISST
                     YTDFDKALKELQAKNIKGLVIDLRNNPGGMLDICKEVADELIGEGTIVYTKDNKGNTE
                     YLKSDKEKLGLPIVVLTNGESASAAEILTAAIVDNKEGISVGTTTFGKGLVQSVVRLK
                     DGTGYKLTTAQYFTPNGDYINEKGIKPTIEEKDENKQLDVATKWLREQIDK"
     gene            96067..>96310
                     /locus_tag="JAM15_01070"
     CDS             96067..>96310
                     /locus_tag="JAM15_01070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAT6796864.1"
                     /translation="MFNKNEILKKLIEEYDVKTTTDIQDMLKDLFASTIHQMLEAELD
                     DHLGYDRYDNKNKNTKNSRNRYRNKNVKSDFGEITLN"
BASE COUNT        38686 a        10349 c        17725 g        29550 t
ORIGIN      
        1 attttttgtg aaaaaaaaca aaaaatatgt atttcttttt tcatttcggg aaaactaaac
       61 acaggaatta tggactttat aaaaatttaa ttcttgagga gtgatataag tgaaaaaagt
      121 tgctttaatt ttagctataa taggtgcgct taactggggc gcaattggta ttctaggtac
      181 agacttaata ggtagtatct ttggtggaac atatgaaatg gtaagtagaa taatatactt
      241 cattgtaggt ttagctggat tatacttaat accaagttta atgtctgatg atagagaata
      301 atttatgctt ttatgttaaa tacctcattc taaatgttta gaatgaggta tttaatttta
      361 taaaaatatt aatttgtttc ttttttaatg gtaaaataga taagaattga agttttaaaa
      421 agaagtatta tgtaaaaaag gagtactatt aatatatgtt tattattaat gaattaaata
      481 agattgtaaa tgaagaagta atatcttttc atatgcctgg tcataaaaag ggacaggttt
      541 ataaaaagtt aggatataaa gatatactaa aaaatttgta taaaatggat acaactgaga
      601 tattaggaac agataattta cactttccgg aaggaattat aaaaaattca caaaaaaaag
      661 catcaagagt atttaaaagt gattatactt gctatttagt aaatggtagt agctgtggaa
      721 tacaatctgc aataatgtca gtatgtagtc ctaaaagtaa aataataaca aatagagact
      781 gtcatcagtc tgttataaat ggatgtattt taggagatat agatatagag tatgtgcctt
      841 gtgagataag tgaagagaca aatgtcttaa aagggatatc tataagtaat gtgattgata
      901 taatagataa aaacttggat gcaaaagcag tactgcttac ttatcctaca tattatggaa
      961 tgacatatga tttagaatac atatgtaatt atgcacatag caaaaagatg gtagtgatag
     1021 tagatgaagc acatggtgcg catttagggc ttagtgagag gcttcctaaa acagctcttg
     1081 agcaaggtgc agatatagtt gtacagagta cacataaaac ccttccagca tttacacaat
     1141 cgtcaatgat acatatacag ggagaccgag ttgatataga taaaatattg aacatgttaa
     1201 gaattacaga atcttcaagc ccttcatatt tattattatc ttctctggaa ttagcagtag
     1261 atatatatga aaataaagga aaagaattaa tggaagagct tttaaataat attagaattt
     1321 tcaaagataa agttgattca aatattaata tatatgacac aaatgataaa acaaaaatat
     1381 ttatatcatc taaaaacatg ggtttaacag gttatgaact agaaaatatt ttgagaaaca
     1441 aatataacat acaagtagag ttatctaatt attatggagt tcttttaata tgtacaatag
     1501 gaaatactgc tgaggatttc tctagtttag aaacagcatt aaacaatgtt gtaaaggaag
     1561 actttaaatt tgaaaagtta gaaaataaaa aataccctgt tgttattcca aagaaaatat
     1621 taacacctag agaagcattt tataaaacta aaaaaagtgt taaaatatat gacagcatag
     1681 gtaaaatttg tggtgaatgt atagttccat acccacctgg aataagtgta atatctcctg
     1741 gtgaagtaat aagtaaagaa ataatagact atctaatgtt ttgtcattct aaaggcatga
     1801 ttgtgagtgg attgaaagat gtagatttaa attttataca agtaatagat ttagaagaca
     1861 tttaaaaatt atgatataaa agtagataga agtagatagt ttaaaattgt gaagagaaat
     1921 aaatagactg cttatataga gctatctaat aaaagtacta aaaaagtaaa aattgtttgt
     1981 atggaggata tgaaaatgaa aggtaagtta ataattatag agagtggttc agatgcaagt
     2041 ggaaaggcta ctcagacaga aatattatat gaaagattaa aaaaagaagg ctatatgatt
     2101 aaaaaggtag aatatccaaa ttatgaatct ccatcatctg ccttagtgaa aatgtaccta
     2161 aaaggagact ttggtaaaaa tgcatcagat gtagacccat atatagcatc aacttttttt
     2221 acagctgata ggtatgcatc atttaaaacc gattgggagg agttttacaa taaaggtgga
     2281 ataattatcg cagatagata tacaacctct aatatggtac atcaggcctc taaaatggat
     2341 atttgtgata gagaagagta tttaaattgg ttagctgatt atgaatttaa tttatttaag
     2401 ataccacaac ctgattgtgt tatattttta gatgtgccta ttgaatttag tgaaaagctt
     2461 atggagaata gaaaaaataa aattacaggg gaagaaaaaa aggatattca tgaaagtgac
     2521 atagagtatt tagagaaatc ttacaacaat gctttatata tagcagataa atatgattgg
     2581 aaaaaaataa attgtgtttt agataacaaa ttaagaagta ttgaaagtat acataatgaa
     2641 atttataaaa tagttcttga ttcaataaaa cctatggaga gataaatatg tattttgaaa
     2701 atattatagg gcaagatttt gcaaagaaat atttaacaaa ttctataaag aaaaataaac
     2761 ttaataatgc gtatatgttt gaaggaatgg atggaatagg aaaaaagaaa tttgcagatg
     2821 aattatcaaa actattactt gattatgaaa atctcgaaaa tagtccagac tatgtactca
     2881 taaaaccaga tggaaatagt ataaaaatag ctcaaatcag aaatttacaa tcagatatag
     2941 taataagacc tcataaagac tataaaatat atataatcaa taatgctgaa aaaatgactg
     3001 tggaagctca aaatgcactt ttaaagacgc tagaggaacc tccaaactat gctataataa
     3061 tcttagtcac aaacaacaag gaatctttat tagaaactat aaaatctaga tgtgatataa
     3121 taaagttctc acctatacca attgaagact taaaacgtta tttgataaat acaggtatag
     3181 aagaagaaag agctcaatta ttggctattt tttcgagagg aagtattgag aatgctctaa
     3241 atctatctca gtcttctgag ttttcaatga tgagagaaga tatacaacag tatattcaga
     3301 taatgttaga taaaaacata gtggagattt taaatatacc aaacaatatg gaaaaatata
     3361 gaggtaagat tatagcttta ttagatatga tgataaacta ttttcgagat atcatcctat
     3421 taaaagaaaa tgtaaacaag aacatgttaa taaatgtaga taagctagtt ttcattcaaa
     3481 atatgagtgg aaaaattagt tattctcaat tgtccaagat tattgatata atagaagatg
     3541 caaagagtaa aataaaaagc aattgcaatt tcaatataag catacaagtt atgtctttaa
     3601 atatatacga ggtgattaaa tgataaagat agtaggtata aggtttaaaa gtgctgggaa
     3661 aatatattat tttgaccctg ttgattttaa tatagagcaa gatatggatg tagttgtaga
     3721 aactgcaaga ggcttggagt atgggaaagt agtcgttggt ccaaaagata tggatgaaag
     3781 cgaattagtt tctcctttga agccaattat aagaatagct acagaagaag ataaaaaagt
     3841 atatctagaa aataaggaaa aggcaaaaga aacttttgag ttgtgccaac aaaaaataaa
     3901 agaacatgag ttaacaatgt ttttaataga ttgtgagtat acgtttgata ggaataagtt
     3961 gattttttac tttacagcag aaggaagaat agattttaga gaattggtaa aagacttagc
     4021 tgctatattt aaaactagaa tagaacttag acaaataggt gtcagagatg aagctaaatc
     4081 tataggaggt ctagggcctt gtggtagaaa actttgttgt tcatcttggt taggtgattt
     4141 tcaaccagtt tcaataaaaa tggcaaaaga ccaaagtcta tctctaaatc caacaaaaat
     4201 atctggaata tgtgggagat tattctgttg cttaaaatat gagcatgatg tatatagtga
     4261 agcaatagaa aaaatgcctg ttgtaggtgc attggtgcaa tcagatgatg gaaaaggaaa
     4321 agttgtagaa gtgaatcctt tattagaaca aattaaagtg gaatttcaag acaagacagt
     4381 aaagatatac acaagagaag atataaaaat acttagagag cctaaaaaat gtgatggctg
     4441 tggtggtaaa tgtaaggata atgatggatt agatgaagcc acactaagag agctaaagaa
     4501 attagaagat taaatttaag gtagggcttt tcctaccttt tttaaagcaa ttaatgctta
     4561 aagttattaa tatttgagga gaatttatat atgcaattaa aagattcaga aagaatagat
     4621 gatttacaat taaaaggcct taaaattata caagatacta atggtttttg ttttggtata
     4681 gatgcagttt tattagccaa ttttactaaa ataaaaaaag atgcaaaagt agtagatttg
     4741 ggtactggaa ctggaattat acctattttg atagctggaa aaagtgaagc taaaaaaatt
     4801 attggcgtgg aaatacaaga agatgtatat gaaatggcaa ctcgttctat aaaattaaat
     4861 ggattagaag aaagagttga gattataaat gaagatataa aatacataga caaagtctta
     4921 gacataaatg gttaccatgt agtcacatca aatcctccat atatgcatat tgatggaata
     4981 aaaaatccaa atgataaaaa agcaatatca agacatgagg taaggtgcaa tttggaagat
     5041 gtaattagag ctgcatccag attggttatg cctagaggaa aattcttcat gatacataga
     5101 ccaacaagat tggttgatat aataacttta gggagaaaat ataaattaga accaaaggtt
     5161 attcaatttg tgcatccaag acctcaaaaa gcaccgaact tagttttggt tcaatttgta
     5221 aaagatggaa gaccagagct taaaatattg gacccattgt atgtttatgg agaagatggg
     5281 aattatacaa aagaattaaa agcaatatat aataataaag atataggaga gttgtaaatg
     5341 agcgggaaat tgtacatatg tccaacacca ataggaaacc tagaagatat aacatataga
     5401 actttaagaa cattaaaaga agtagacttg attgcagcag aagatacaag acatagtata
     5461 aaacttttaa atcattttga aatctcaaaa ccactaacta gttatcatga acataataag
     5521 gattcaaagg gagattattt gataaataaa ctaattgatg gtgaaaatat agctctgata
     5581 agtgatgcag gtatgcctgg tatatctgac ccaggagaag agataataaa acaagctata
     5641 caaaataaca tagagataga agtattgcca ggtgcaacag cctttgtaac ggctttagtt
     5701 ggctctggta tggacacaca tagatttgtt tttgagggct ttttagatag agataaaaaa
     5761 gttaggaaag cacaattgga agaattaaag gaagaaagta gaactataat tttctatgaa
     5821 tcaccacata gattgaagga tacactaaaa gatatgctta aaattcttgg taataggaat
     5881 atttctataa atagagaact tacaaaaaaa tatcaagaaa taataagaga aaatatagaa
     5941 actaccataa aaatatttga ggaaaaagaa gtaagaggag agtttgtatt aatagtagag
     6001 ggttttcatg gtgagaagtc aaagaaagaa aattatgatg ggcttacaga tagggaatat
     6061 gttttaaaac taattgaaag tggtatgaac aaaaaagatg caataaaaat agtttgtaaa
     6121 gatagaaagt taaagaaaga tgtggtttat aaacaagttt tagatttata aaacctgaat
     6181 ctgaggtgat tttatggaaa taggaaaaat tataatagag agtttaaaga gggaagatac
     6241 acataaaata tttatagaat tagataataa gcatgaatta gaaaaaataa ttcctaaaat
     6301 aagctgtatg aagtctgtag gtgaatgtaa atatcatgta gtaaattgtt ttgaacattc
     6361 tataaatgca ttaaaagaat tagaaatagt attaaatgat aaggattttt ttccaataca
     6421 tctaagaaaa catgtgtcaa actatttaaa cacatatatt gaagaaggaa taaataagtt
     6481 acatgtatta aagctgggaa catttttaca tgatataggt aagcctgata gtatgacctt
     6541 agatgaaacc ggaagagttc atttcacaaa tcatgaaaaa ataggtgctc aaataattga
     6601 caatatggga ataaagttag agttatcaac aaagacatat agacttataa gtaaatatgt
     6661 aagatatcat atgatacttt tgtctctata taagaaaaat gatttgagta ggaaagaatt
     6721 aattaatgta tttaacttag tagatgagga cactataggt gtaataatgc ttgggtatgc
     6781 agatatagtg tctacagtaa aattattggg caagagtgga gaagtcagtg tgttaaagac
     6841 atatatggaa tatattttaa caaattactt gtataagagt aattatacac atgtataaat
     6901 ttagttaata taattgagtt ttagatgatt aattgaagtt tgaaatatac ggatttcaaa
     6961 aacataaaag aagttgtctt tgttgtaaaa ttgtgaaaga caactttttt tatatcaaaa
     7021 attgaaattt tattaaggat acttaatggt ctattaatta ataaaccatt agtatttaat
     7081 ttatattaca atattgattt tgcttgtatt ggtgttgata gtataacaga ggtcttagta
     7141 gaaccaattt tctttatagt atcaatcaca ttttctagct cgtacatatc ttttacaatt
     7201 acttttaaaa gtaagcaatc atcacctgtt atatggtgac attctacaat cctagggtcc
     7261 tttgcagctg actcaataaa ttctgtatat ccattgcttg gaagagaaat atgaataaat
     7321 gcctttataa ctctgcctaa tgaatctggg ttgacaatag ctttatatcc ttctataaca
     7381 ccagactctt ctaatctttt gactctttct gaaactgcag gagaagttaa accaactatt
     7441 tttcctaagt ccttcataga aattctccca tcatcctgta aaatttctat gattctgtaa
     7501 tctgtaacat ccataaataa acagtccccc ttaaataaaa ataattaatg ctataaaact
     7561 tttttagaat ctatcatttg tgtttttaaa taccaaagat ttctagataa atcaacctta
     7621 taaatgtgtg gttttgaaag tcttttgtat tgttcccaga tagtacttaa ttcatattgt
     7681 acatgatttt ttatttcaag aacagctttt ttattatatt tgcatctgcc ttttatatac
     7741 aatggtttaa gaagctcttt aactttgtaa tttgtaaata cctttgtttt ccatgtataa
     7801 gtaggatgga agatttctaa aggtttagac tcatctataa cttcatcatg taacataatc
     7861 aaatctgcct ctgccttatt gtcttcgtta tatattctta taactttctt gtaaccagga
     7921 ttatttattt tttctggatt ctcagaaatc tttatcttag gttcaagaac tcctttttca
     7981 caagatgcag ctaatttata aactcctcca agagaaggtg aatcgaaaga tgtaatgagc
     8041 tttgtaccta ctccccatga atttatagta gctccttctg ctttaagtga tgttatggta
     8101 tattcgtcta ggtcattaga tgcagtgatg ctgatatctg aaaagccagc gttatctaat
     8161 tgttttttag cttctttaga taaataagct aaatctccag agtcaagtct tatacccata
     8221 ggtttgtatc ctttttcaga aatatttttg aatactttta ttgcattagg aactccactg
     8281 tttaatacat cataagtatc tacaagtagt aggcatttat ctggataaac atcagcatat
     8341 gcttggaatg cttcaagttc attatcaaat ttttgtaccc aactgtgagc ttgtgtacca
     8401 attataggta tatcaaacat tttccctgct agtacgtttg cagttccagc acaaccacca
     8461 actacagcag ccctagctcc atatatccct gcatctggac cttgtgcacg acgtaatcca
     8521 aattcaaata cagggtctcc ttgagctgca aagcaaactc tagaggcttt agtagcaata
     8581 agagactgaa aattaactat tgttaacaat gctgtttcaa taagttgagc ttgatataaa
     8641 ggtgccttaa cagtaattaa tggctcatta gggaacatga tagttccttc ctcaacagca
     8701 tatatatctc ctgtgaattt aaattctttt aaaaatttta aaaacttgtc agaaaataaa
     8761 tttaagtttt ttaagtactc taaatcttca tctgaaaaat gaagattatc tatgtattca
     8821 acaacctgat caataccaca aactatagta taccctccat cacaagcgtt ttttctaaaa
     8881 aacatatcaa atacaacaat gtcttcatga atattctttt caaaatagcc atttaacata
     8941 gtaagctgat ataaatcagt aagaagtgtt agatttctca ttatttctct ccttaattat
     9001 tattaaatat taaaaattgt aaaaactccc acacttatac taaaacataa tatagtacaa
     9061 ctttcaagta taaagtatta cctaactatc ataaaattat ttaaagagga ggatgattat
     9121 aataggaaaa atatggtttt atatggtatc gataggaata ataggaagct tgatttctaa
     9181 aaatatgggt gaattaaata aagttatatt aagtgaaaca tcaaaaggta tagagtttgc
     9241 aataagtcta gctggtatca tggcactctg gatggggata atgaatatcg caaaagaatc
     9301 aggtttaatt gaaaagatag gtcaaaaact aaatcctata atgagaagat tatttccttc
     9361 tattccaaag ggtcataaag caatgtctta tatagttatg aatattgctt taaatatgtt
     9421 gggtgctgga aatggtgcaa cagcatttgg tttaaaagca atgagtgagc ttcaaacttt
     9481 gaataacaag aaagatacag ccactaatga tatgattatg tttatggtaa tcaatatatc
     9541 atctatacaa ataattccat ttactataat caaattaagg atggatatgg gggctcaaaa
     9601 tccaagtgaa ataattttta cgactttatt tgcaaccata atatctacag cagtagcaat
     9661 aataacatgt aaattttttc aaagaagata tagataaagg ggatgtagat acatggagat
     9721 attttcaaac ttacttatac caataataat tctgtacata gtagtttatg gtaaatataa
     9781 aaaaatagat gtgtatgata gttttgtaaa aggagcaatt gatggattaa aagcagcatg
     9841 ggatatccta ccatatataa taggtatatt tttggcaata ggaatattca aaactggtaa
     9901 aggtcttgat atgttagaat ggctatttac accaatagca aatatgatga gtataccaaa
     9961 agaattaata ggtctaataa gtgtaaaacc tttatctgga agtggtgctt tagggatgta
    10021 cagtgaactt gcaaatagag ttggaatagg aagtttagta gaaaaaatgg gtgctacgat
    10081 tgtaggttct tctgagacta ttttttacac aatggcaata tactatggaa gtctgaagat
    10141 aaaaaatact agacatacat tatcatgtgc tatgattagc catgttgcag gtgtcatagc
    10201 agctgttttt atttgctatg taatatttgt ataatttgtt gacaatatgg gaaaaatttt
    10261 ataatatagt gattatatag aaacaaatag taatacaaat tacaagctat gaaaagaaga
    10321 gtaaataaag gttttttcta tcagagagct aggttaggtg aaagctagtg tcaaaagctt
    10381 tattgaagat ggtcttggag ctttttatct gagcaagtat gctagggtaa aacggttgga
    10441 cacgttatag tctactaagg tatctataaa atgtttctac atttcatgtg aaacataact
    10501 attatagatg aattagggtg gtaccgtgaa taatctcgcc cctatgttaa ctcataggag
    10561 gcgatttttt attatttaaa tgaaagaatc atatgattac gaacgataaa aaattaggag
    10621 gtaaataaca tgagcaaacc gagtttttat gtaacaacac caatatacta tccaagtgga
    10681 ggattacaca taggacatac ttattcaaca gtagctgcag atacaatagc tagattcaag
    10741 cgtttctgtg gatatgatgt aaagttctta acaggaacag atgagcatgg tgaaaaaatt
    10801 caaaagaaag ccatagaaca aggaatgtca gagatagagt atcttgatgg aatgataaaa
    10861 gatataaagg ccttatggaa tactatggat atatcttatg atgattttat aagaactaca
    10921 gaaaaaagac atacagacat aatacaaaag atatttacta aactatatga gcaaggtgat
    10981 atatataaag gtgaatatga aggtagatac tgtactcctt gtgagagttt ctggacagaa
    11041 tctcaattac tagaaggaaa taaatgccct gactgtggaa gagaaacata tttagtaaaa
    11101 gaagaatctt atttctttag attatctaaa tatgaagaca gattaaaaga gttatttaaa
    11161 gatgatagtt tctgttttcc tgctgctaga aaaaatgaaa tggtggcaaa ttttttagac
    11221 aaaggattag aagatttaag cgtaactaga acgacttttg actggggtat aaaagttcct
    11281 tttgatgaaa aacatgtaat ttatgtgtgg gtagatgctt tatgtaacta tataacagca
    11341 ttaggttata tgactgataa tgatgaagaa tttaaaaaat attggcctgc caatgttcaa
    11401 atagtaggta aagaaatagt gagattccat acaataatat ggccagcgct tttaatggct
    11461 ttaggtctag aagttccaaa acaagtattt ggacatggat ggatactatt tgctgatgat
    11521 aaaatgagta aatcaaaggg taatgtggtt tatccagaac ctataataga aagatatgga
    11581 atagacacac ttaagtactt cttattaaga gagtttgcat ttgggcaaga tggaagttat
    11641 actcatagaa attttgtaac gagaataaat tatgatttag caaatgattt aggaaactta
    11701 ataagtagaa ctgtagctat ggttgaaaaa tacaataatg gtataatacc aacagcaaaa
    11761 gtttcaactg attttgatgc tgacttaaaa gaacaagctg tttcaactag agaaaacttt
    11821 gaagctgaaa tggataaaat gcaattccat gaagcattag agagtgtatg gaaattagtt
    11881 agaagaacta acaaatatat agatgaaact atgccttggg cactagctaa agatgaaacg
    11941 aagaaagatg aattagacac agttttatat aatttatgtg aatctataag aataatcgca
    12001 acactaataa atcctataat gaatgagact gctaataaaa tatatgaaca tataggaata
    12061 aaaggtcaag atgatataac tacatgggaa agtacaaaaa catttggtct tattggagaa
    12121 aatgtaaaag tatttaaagg tgaaccttta ttcccaagat tagatgtaga aaaagagata
    12181 gaagaattaa ctaaaatgtt ctctgggaaa cctccagtag aagaaaaacc tttagagcat
    12241 aaagaagaaa ttactattga tgatttagac aaaatagagc ttagagtagg gaaaataata
    12301 agctgtgaaa aacatccaaa agcaaataaa ttattagtat cacaagttaa gattggacca
    12361 gaaacaagac aaatagtatc aggaatagct gaatactata agccagagga tttagtagga
    12421 aaagaggtta cagtggtatg taacttaaaa ccagttaaat taagaggtgt agaatctcaa
    12481 ggtatgatat tagcagcagg tgatgatgga gacccatatg ttttgccatt tacacaaggg
    12541 gctaaagatg gatgcgaggt tcgttagtag gtaattaaat agtaaggaga ttaaagatgt
    12601 tatttgactc acatgcacat ttaaatgatg aaagttttga tgaagataga gatgaactta
    12661 ttggttcatt aaaagataaa ggtgtagatt tggttgtaaa tccaggagca gatatagaga
    12721 cgtcgataac agcaattgaa cttgcgaaaa aatacgactt tatatattca gcagttgggg
    12781 tacatccaca tgatgtatca aaactagatg atacagcaat agaaactcta agaaaacttg
    12841 caactgagaa tgaaaaagtt gtagctattg gagagattgg attagattat tattatgatt
    12901 attctccaag agaagaacaa aaagagtggt ttaagaagca aattgaatta gctaatgagc
    12961 taaaacttcc aataataata catgatagag atgcacatgg agatactttt gagataataa
    13021 agaatactaa aaatcctgaa ataggatgtg tacttcattg ttatagtgga aatgtagagt
    13081 tagctagaga atatgttaag atgggttgtt atatatcaat tccaggcacg gttactttta
    13141 agaataataa aaaaactaga gaagtagtaa gagaaatacc tctagaaaga ttattcatag
    13201 agactgattc accatatatg tcaccagagc cacatagagg aaagagaaac aatccttctc
    13261 aagtatcttt tgttgctgat aagatagccc aggaaaaagg gatatgttat gaagaagtat
    13321 gtagagttac aaaagaaaat gcaaagaaat tttttaatat aaaatagaca aattaaatct
    13381 tataatgata tatataataa gtcattataa gtataggatg agagtgcctc aaaatgagtt
    13441 ttttagttca tgaggcactc ttttttgtat gaaatcaaat atattttcat catttcaaca
    13501 atgaaaaaga agtttatcat attttgagac agtttgtttt tatttgttta attcatattt
    13561 taaaatatat tttcttaaca ttgttaaaaa agaatttaca agatattcat tagaattaac
    13621 tcaactctaa tattcactta acttaagtgg tttattatat tattaaagag aagtaaacga
    13681 aaggtagatt aaggaggcta aattttgtat acagttgata gtactaagat attgataaat
    13741 atgaacttag agaaactaga aaagatatac tcaatgataa aagatacatc aagtatttct
    13801 ataattaaag aacctaactt ggctacagta atggtaagag ctaatgaaag tgtaaaaaat
    13861 acaacattta atttaggaga gatattagtt actgaatgta gtgtaaaggt agatgaaagc
    13921 ttgggttacg gaatagtttc agaaaacaat aataagaaag ccatttactt agcagttata
    13981 gatgcagttt tacatagcaa taacagtaaa tttgatgagt taaagaatta cataaataaa
    14041 agtgtatatg aagagaactt aaggtatgaa caagagatta ttgatgaatt tagcttgatt
    14101 aataaaacga aagttcaatt caatgctatg gattaaatag gaggagaatc atggtaaatt
    14161 atacacaaga aatatataga aagatgctag atagtgcttc atttcctggg aaattaaata
    14221 atatagataa tataaatata gaaaataata caaaactatt gaatggagca attggtatag
    14281 caatcacttt attagaccaa gaagttacct tctatataga aaattatact caaaaagata
    14341 taaaaaatat aagagcgctt acaatgtcaa atcaaataga ttatagaaaa tcagactata
    14401 tatttttaga tattaattca gaagtggata tattacagat taaaataggt tcttttgaat
    14461 atcctgatga aagcgcaact atagtacatc aagtaaatga tttatcaacg tactctcaaa
    14521 ctaagtatat aaagcttgat ttgagtggtc ctggtataaa atctaaaaat agtatatata
    14581 taaatggaat tagagaagaa tttatagaaa gattatctac cataaataaa gattatccaa
    14641 taggaataga tttgatttta gtagataaaa aaggagaaat tgcatttata ccaaggtcat
    14701 caaaattaag ttgggaggta ttgtagaaat ggcttatgta gcagttaaag gtggagaaga
    14761 agccatatta caggctaaaa atatacttga gttttatagg gtaaaaggag atagcttgcc
    14821 tatagatgta aagcagattg aggaacaaat gtcttatgct gtagacaaag taatgtctga
    14881 aggaagttta tacaacaagg aactatcagc attggctata aaacaagctc aaggtgatat
    14941 attagaagcc tctttctatg taagagcttt aaggtcaaca atgcctagaa ttacatattc
    15001 agaacccata aatacagaag aaatgagaat aaaaagaaga atatcagcta cttttaaaga
    15061 tataccagga ggtcagtatc ttggggcaac tagagactat gaaaatagaa tattaaatgt
    15121 agaattatta gaagaagatg aaaaaaagaa tagagatttt agagatagtt ttataaatga
    15181 attagaaaca gtagatgaaa tccctgaatt tacaaaaata tctaatatat ttagaaaaga
    15241 aaatttatta caagaagaag tttgtgaaaa caaattggaa gaagttattg atgatattac
    15301 aagaaatagt ttaagatttc cagtttctag gtcagcaaag ttacagacat tgactagagg
    15361 tgaaagtgga gtagtgtcag gttttgctta tgctattgta agaggttttg gtgatgaaca
    15421 tccatatata agtgaactta gaactggtaa tgtatttata aaagtaaaac atcccatcta
    15481 tgaagatgaa gaaataataa taggtgatat gctggttact gaatgtgaaa tagtttcaaa
    15541 agcatcacaa aataagactg aaaattctaa aactaattcg gaagataaaa ataagatgtc
    15601 tttaggatat ggtctttgta tggggaataa tgagaataag gctatatcta tggccatact
    15661 agacaaatct ttggagccaa atagtgaaaa actagcacaa gatgaagaat ttgtattgct
    15721 tcatatagat ggaatagatt cattaggatt tatatctcac tttaagcttc ctcactatgt
    15781 agattttaaa gcggatgtag aaagaataaa atagtttgtg gaggtaagtt taggtgatat
    15841 ataactatgg ttttttagac gaaaacacaa aaaaagaaat aagaagaaag atattaaaag
    15901 caatatcaat acctggttat caagttccct ttggttcaag agagttgcct atagctaagg
    15961 gatggggtac tggaggttta caattaacac tatcattaat tggtaaaaat gatgtagtaa
    16021 aagtaattga ccaaggaagt gatgattcta caaatgcttg taatataagg agctttattg
    16081 caagtgtaag taatgtagaa accacaaaag atacattaga agctacattg attcaaacga
    16141 gacatagaat accagaagaa aaacttaaat ctaatcaaat actaatattt caagtaccaa
    16201 taccagaaac ccttagaata gtagaaccta gtgaagtaga aacaagaaga atgcattcag
    16261 aagaagatta tagtaggatg tgggtatatc tttatgaaga tatagttaga tttaatgata
    16321 tatctatagc agttgaatat ccatgtaaag taaatgatag atatttaatg aatccatcac
    16381 ctatacctag atttgatata aaaaaattaa atatgtcaga caatttattc ttgtttggtg
    16441 caggtagaga aaaaagaatt tatgctattc ctccatatac aaaggtagaa cctttagagt
    16501 ttgaggatta taagtttgaa gaggaaaagt ttgaaggaaa atactgtagt ttatgtaaca
    16561 gtacaaatac atttttagat gaagtatatg acagtgacac taatgaaaag tactatagtt
    16621 gctcagatac aagttattgt gaaaaagtta gattaaaaaa taacagtata gatgtgacaa
    16681 taggaggtac ttggaatgag taaaataaat gtctctaaaa gattagaaaa tatagacaag
    16741 caagtattaa taggaagaaa tatcaatctt atttatggag atgggtgtga aaagtgtttt
    16801 gaaagcacag gatatgaaag caataatata tgtaagtatt gtggttctat agttgcatgt
    16861 aataatgtaa atttagaact ttatgaagga gaagtccttg gaattgtagg tgaatctggt
    16921 tcaggaaaaa gcactttatt aaaaatactg tttttccaag aacatgcaaa tagtggagaa
    16981 gtatatatat cccattacaa taaagacaca aatatactag agctttcaga ccaaaaaaag
    17041 agatacataa agaatcattt tatgggtatt gtgtatcaaa atccccacct tggtttaaat
    17101 ttagacttta gtagtggtgg taatatagca gaaaaattat tgatggcaaa tttatataat
    17161 gttgaaaaaa taagagatag aggcaaagaa cttttaataa aaactaatat acctgtagaa
    17221 agaatagatc ataaaccaaa atactttagt gggggaatgc aacaacgagt tcaaatagca
    17281 aaagctcttt caaataaccc tccaatattg ctattagatg aggttacaac aggtttagat
    17341 gtttctgtgc aagcggaagt attagattta ataagagaaa tccaaagaga acttaagatt
    17401 tctatgatag ttgtatccca tgactttgat gttataaaga tgcttgctga taggacaatt
    17461 gtaatgaaaa atggaagtgt gattgagtct ggtcttacag accaaataat ggaggaccca
    17521 caacacccat atactcagca acttataaat tcattgctat aaatatcgtt tgtaaataag
    17581 caaaatgggg gtttttaata aaatgaaaga aactatactt gaagtaaata attttagtaa
    17641 agactttgag ttacatgcat tgaacaagac tataacggca tgtagtaata taagttttga
    17701 agtttcaaaa ggtgagtttt taggaataat aggtaaatct ggagcaggta agtctaccat
    17761 attaaaaagt atctataaaa catatatacc aacaactgga gaaataattt ttaattcaga
    17821 aatatatggt aatgtagacc tggctaaaat tggagaccga gaaatgataa atcttagaaa
    17881 gaaagaaata ggatatgtat cacagttttt aaagacactt ccacgaataa ctgcaattga
    17941 actggtagta cattctttaa ttgagagtgg gtttgaaaaa gattgttcgt atgatatggc
    18001 aaaagatata cttaaccaat ttgaaataaa ggaaaattta tgggatgcgt atccaaataa
    18061 tttttctggt ggagaaaaat taagattaaa tttagctcaa gctatggtta aaaagcctag
    18121 acttttgtta cttgatgaac caactgcatc acttgataat caatctaaaa tatatgtaaa
    18181 agaaaaaatg ttggaactta aaagtcaagg aactacaatg ataggaattt ttcatgatat
    18241 agagtttatg gaaactgtta tagataagac ctttactatg gcaaaaggga ctataagtga
    18301 aagtggggta gcctagatga taaaactaat tcataatgca aatattgtat tagaagatat
    18361 gattttagaa aatggtcatt taatcataga gggagataca ataaaaaaag tatcaaatga
    18421 taggattgat tatgcatttg actttaatga gatagatgaa ataatagatg caaaaaactt
    18481 atatgtaata cctggtatta tagatattca cagtgatgcc attgaaaagg aaatagagcc
    18541 aagaccaagt acattattac catttaatat ggcattttat gaactagata aaaaactacc
    18601 tgcaaatgga ataactacag tttatcattc tatatcttta ggggatggag taggagttag
    18661 aagtattgat aactctttaa agatgattaa aaatattgat tcatataaaa atatagatag
    18721 taagagcata aatcataaag ttcatttaag atatgaagtg ttgtattatg aaggtttaga
    18781 aaaggtttta gaactattag atgaaaataa aatagactac ttatcaataa tggaccattc
    18841 tccaggacaa ggtcagtata caaatccaac attttataaa gagtatgcta ctaaagtgtg
    18901 gggagttaca gaaaattatg tagatacatg gttagatgat ttagtaaatc tgcatgataa
    18961 tttagattgg aataaaatag ctaatattat aggtatagcc aaaactaaaa atataaatgt
    19021 tgcatcacat gatgatgata cattagaaaa aatggatttc ataaaaaata taggcataaa
    19081 tgtatctgaa tttcctataa ctcttgaagt tgcaaaacat tcaaagaaat tgggtgttct
    19141 aacttgttta ggtgcaccga atattgtaag aggtaaatct cataataaca atttaaaagc
    19201 aatggatgct atattggaag attgttgtga cattgtgtgt tcggattatc ttccatcagc
    19261 tatgataaag tctatgtgta tagttgcaga aagaataaat aatttaaata aagcagtcag
    19321 tttatttacc tcaaatcctg ctaaagcagt tggtatatat gatgaaagag gtagtataaa
    19381 agaaaataaa aaagcagatt tagttttagt agatattgat agtgaatatc caaaggttgt
    19441 aaatactatt gtaaatggaa aaacagttta taaaagggag gtataaagat tgctaacaga
    19501 gttacattgt catacaagta tatcagataa taattttact actgaagaaa taataaaaaa
    19561 agcagcagaa aagaatataa atatcttagc aataacaaat catgacacat tatctggatt
    19621 ggatgaagct cttgtgcttg gagagcatta tggaataaca ataataccag gtatagaaat
    19681 ttcagcctat gattataaaa atagaaaaag agttcatatt cttggatata acatagattt
    19741 aaacagtcaa gaaataaaaa atttgtgcaa tccaatggta tgtgacagac ataaagcatc
    19801 tgttaagatg gtaaataaaa ttatagattt aggatacaaa atatctttgg aagatgtaaa
    19861 gaaatattca tcaaagactg gaatatttaa acaacatata atgaaagctc ttatagataa
    19921 aggatataca gataatatat attcaagtct atataaagaa ttgtttcata gaggaaacgg
    19981 caaggtatat gtatctttaa aatatgtgga ttacagagat gcaataaaag ctataaaaaa
    20041 ttctggtgga atttgtgtgt tagctcaccc gggtcaaatg gataatttta gtgctattga
    20101 agagatggta aaagtaggat tagatggaat agaagtatat catccatctc acaacaaaga
    20161 actagaaaaa gagtcgcttt cttatgctaa gaagtataat ctagtggtca caggaggctc
    20221 agattaccac ggattttatt ctcaacataa ttatgaactt ggaagcaaga gcttaaataa
    20281 agaagattta tttaagttta ggttagcttt aggaggggta ttataaatgt cttttttaca
    20341 agtaaaaaat gtaggtaaaa gttatggaca agttaaggtg ttaaaagaca tatctattga
    20401 tattgaaaaa ggagagttta tttgtttact aggtccaagt ggttgtggaa agagtacact
    20461 acttagaata attgcagggc ttgaggataa acatggtgga aaaataataa taaatgataa
    20521 ggatatgact aattcaccac ctgaaagtag aaattttggt atagtttttc aatcatatgc
    20581 attatttcca aatatgaatg tttacaaaaa catagccttt ggactagaaa ataaaaacat
    20641 aagtaaatct aatattgata aaaaagttaa agaagttcta gacgttgtag aattaagtgg
    20701 atatgagaaa aaatatccat cacaattatc aggtggacaa caacaaaggg ttgcattagc
    20761 tcgtgcgatt gctttagagc cagacttttt acttcttgat gaacctttat ctgcattaga
    20821 tgcaaaagta agacttaaac ttagggagca gattagaagt ttacatagaa aactaggcat
    20881 tacaactata atggtaacgc atgaccaaga agaagctctt tgtttagctg ataagatggt
    20941 tgttatgaat agaggagaaa taatacaagt tggaacgcca aaggaggtat ataaaaatcc
    21001 agaaacacct tttgtagctg attttatagg gacaataaat tttatagatg atggtattaa
    21061 taagatagct attagaccag aagatataaa agtagagtct aatagagatt ctaaagataa
    21121 ggatataaaa gtgggagaaa ttttagatat cgaatttaga ggatttaact atagaattac
    21181 agttgagtat cgttctaagc aaatgaaatt agatgtagtt tccaaagttg cagaacaaat
    21241 gaaactatgc ataggttcta aaataaactt taagatacct aaagaaggaa ttgtacaata
    21301 taaatcagag ggatgtgctt aatagctagg ggtgaataaa tgataacatc aaaaaataaa
    21361 agaagaataa gtgatagcac aatacaaaaa tatttcttga ttttttcggt aattgtacta
    21421 atagtattta tattatttcc attagtatca ttattaaaaa atgcatttat ggatacaagt
    21481 ggaaatttta taggaatttc aaactttagt aaatatgttg aaaatccaag tcttatagca
    21541 tcatttaaaa attcaatttt tgtatctaca gtctcatctt taatatcact atgtttagca
    21601 tttatatatt catacgcaat aacaagaaca aacataaagt ttaaagattt ttttaaaact
    21661 atgggaatgt ttccactttt tgcaccaact atgttatatg gtatttcact tatatacctt
    21721 tttggaaata agggaatctt tacaaccatg ggtctggaag taccactata tggtccatta
    21781 ggaataatta tttctcagat tctatttaca tttccacaag cttttttaat attatctgta
    21841 gcactttcga tggctgatta cagactttat gaagcagcag atagcttggg tgctagtgaa
    21901 tttaagaaat tttgcaaaat aacaattcct ggtataaagt actcattact tagttcattc
    21961 tttgtatcct ttatacttgc atttacagat tttggagcag ctaaggtagt cggaggaaac
    22021 tacaatgtac tggctactga catatataaa caagtagttg gacaatttaa cataccaatg
    22081 ggagctactg tttctatggt aatgttaatt cctgtactaa tagcatttac attagataag
    22141 atggcaagta agaaacaagg tatgaccata actgcaaagt ctatgccata taagattaag
    22201 gaaaataagt ttagagatag agtattttta atagtatgta gttttataac attgctaatt
    22261 tttattttaa tattcgtttc agttataggt tcagttataa agttatggcc atataattta
    22321 agctttacaa tggaacacta tacatttaaa ggtattttgg gaagtggaat aaaaacatac
    22381 ttaagcagtt tgaaaatatc aactttaaca gcaatatttg gaactatatt tgtatttttt
    22441 agtgcttata tgatagaaaa ggtggataag tttcctaaat taagacaaac agcttacctt
    22501 ttatcaatga taccaatggc cttacctggc ttagttttag gtatatcata tataactttt
    22561 tttaactcag caagtaatcc attaaatttt ttatatggaa gtacagcaat attagttata
    22621 gtaaatgtag ttcattttta ttcagtttgt tttataacct caaattcatc tttaaaaatg
    22681 ttggataaag agtatgaatt agttgcaaaa tccataaata ttccattcta taaagtattt
    22741 tttaatataa cagttccgat gtctataaca tcaatacttg aaatagtagt atattatttt
    22801 gtaaattcaa tggttactgt ttcagcatta atatttttat atacacctca aactcagact
    22861 gcatcaatat caatactaaa gttagatgag ataggatata taggaccatc agctgctatg
    22921 gcagtattag tgctattaac aaatataata gtaagacttt tgtacgaatt tgtaacaaag
    22981 aaattaaaaa ataacacaca aaaatggcag caaaaagatg ctgcataggg gaggaaaaaa
    23041 tgaaatttaa aaagctagtt tctttaggag tattatcaac acttttatta agtgtaataa
    23101 caggatgtag tactgattca tcaggttcag attcaaagtc tgatagtaag acaaaagggg
    23161 atttaacagt ttacacagca attgaagaag atagtataga gccatattta gctacattta
    23221 aagagaaata tccagatatt aaattaaata ttgttagggc atcaacagga gatataacag
    23281 caagattatt agcagaaaag gataatcctc aagcagatgt tgtatgggga gttgcagcca
    23341 caagcttatt ggttgcagat gaccagggga tgttagaacc atatgctcca aaaggttctg
    23401 aagaaataga gtctgcattt aaagatgata aagaagttcc ttcttgggtt gggatagatg
    23461 cttggatgac aggtataaca gtaaacacta aagaattaag tgataagaac atcccagttc
    23521 ctagttctta cgaagattta ataaagccag aatataaagg tcttatatct atgcctaatc
    23581 catcttcttc tggtacaggg tacttaacag tatcagccct tatacaaatt atgggggaag
    23641 aaaaagcatg gcagtatatg gataagttgc atgagaatat tggtgtatac actcaatctg
    23701 gttcagctcc agctacatca gcagcttcag gagaatatcc tattggtata tcttttggat
    23761 atagaggtat aaaattaaaa gaggaaggct atccagtaga agtagtattt ccaaaagaag
    23821 gttctggatg ggatatagaa gcaaatgctc ttgtgaaaaa agataatata aaagaagcat
    23881 caaaagtatt tttagattgg gctataagta aagatgcaat gaatgaatac tctaagaact
    23941 atgcagttac tactatttct acaggaaatc caataccaga aggattccct aaaaagccat
    24001 tagagcaaat gatagataat gatttaaaat cagcagcaaa aaatagagaa gatatactaa
    24061 ataaatggat atcaaaatat gatggtaaga cagaaaaaga gagttaagta aaactataca
    24121 aatggagtaa aaagaaaaaa tttttttaag tagattttat tataataata taagttgaga
    24181 ataatatagg tcaagaaaag tgaatattct ataaaaatgt atagagtaag tataccattc
    24241 agtttgaatg gtatattttt tatttttaga gattaattta gaaatagata tactacagtt
    24301 taaaatagta tattttaatt tcattattaa agtatagatg ttatatataa agtaaataag
    24361 atattaaata attataaact aaagtaaata aaatattgag cgattattaa aaagatatat
    24421 atatatattt taatttgagc agtttgttat atattataaa aaaagagaaa aataaaaggt
    24481 aaattgtttc tggataactt aaaattggaa gtaagaatat ttaactagag aagaattatt
    24541 taagttcagg ttagctctag gagtagctga ttttatagga gcaatagatt ttatggatga
    24601 tgatataaac atgatagcaa ttagaccaga agatataagg gtagaattta atagagattt
    24661 caaagaaatt atagacctca aactcagacc gtatcgatat aaaaactaaa gctagatgat
    24721 atagtgttgt atataggacc atcagctgtt atggcagtat tagtgctttt aacaaatata
    24781 atagtaaaac ttttgtatga attgataata aaaaaattaa aaaccaagac ataaaaatgg
    24841 caacaaaaag aagttgaata agggaggtaa aaatgaaatt taagaagtta gtctctttgg
    24901 gaatattatc aacactttta ttgagtgtaa taactggatg tagtaatgtt tcatcaggtt
    24961 caaacttaaa gtctaataat aagacaaaag gagagttaac agtttataca gcaattgagg
    25021 aagatagtat agatacatac ttagctacat ttaaagagaa atatccagat attaaattga
    25081 atgtacttag attatcagta ggaggtataa cagcaagatt attagcagaa aaagataatc
    25141 ctaaagcaga tgtgttatgg ggtgttgcag ctacaagttt gataatttta gatgacaaag
    25201 aaatgctaga gccatacgct ccgaaaggct ttgataaggt aaatcctgca tttaaagatg
    25261 ataagaaagt tccttcttgg gttggaatag atgcttggat gactggtata acagtaaata
    25321 ctaaagaatt aaaagctaaa aacatatcag ctcctaattc ttatgaagat ttaataaagc
    25381 cagaatataa agatcttata tctatgccta gtccagcttc ttcaggaaca ggatatttaa
    25441 cagtatcaga actcatacaa attatgggtg aagaaaaagc atggcagtat atggataaat
    25501 tgcataaaaa tattggtgta tacactcagt ctggttcagc gccagctata ttagcagctt
    25561 caggagaata tcccattggt atatcttttg gaaatagagg tataaagtta aaaggtgaag
    25621 gttatccagt agaagtagta tttccaaaag aaggttctgg atgggagata gaatcaaatg
    25681 cacttgtgaa aaaagataat ataaaagaag catcaaaagt atttttagat tgggctataa
    25741 gtaaagatgc aatgaatgag tattctaaga attttgcagt tactacaatt gacacgggaa
    25801 atccggtgcc agaaggattt ccaaagaatc cattagaaca gatgatagat aatgatttaa
    25861 aatcagcagc aagaaataga gaggctatac taaataaatg gatagaaaaa tatgatggaa
    25921 agacagaaaa agagagctaa gccttacaat aaaatttagt acaaaaagcg cctagaatat
    25981 aagttttaca tctaggctct tttgatatat ttatttaaaa tgcatatttc tatataaaaa
    26041 taaatagttt agtaccttga ttaaattaaa taaaaacctt aaaataaaga gatgtaaaga
    26101 aaaactaaaa acgaataaaa ggtgaattta tatgataaaa gaaataatag tagtagaggg
    26161 tagagatgac gttacagcag ttaagagagc aatagatgca gaacttataa ctacaggtgg
    26221 atttggattt ccaaaaggtg taatggagcg tataaaagct gctaatgaaa gacgtggtgt
    26281 tataatattt acagacccag attttgcagg tgaaaaaata agaaaaaaaa tagcatcaga
    26341 agttccagga tgtaaacatg catttctacc aagagaggaa gctaaaaagg atggagatat
    26401 aggtattgag aatgctactc ctcaaagtat aatagcagct ctgaataaag ttagaactga
    26461 aaatacagaa aaaagagatg aatttaagca agttgactta attagaaatg gtcttatagg
    26521 taatgaagaa gcatcactta gaagagatgc acttggaaaa atacttggaa ttggatatgg
    26581 aaatgcaaaa caatttttaa atagattgaa taattatgga gttgaaagag aagaatttat
    26641 agatgcatta aaacaaatct aaacgtaatg tttaatgtat gaaaaatatg tatataaaat
    26701 aaattgtgga attacggtta atttaagata aattatttat aatatatacc ttattttaaa
    26761 tcaatgtaaa tacatataaa taagtataat taataaaatt aaatatcaaa ataagttaaa
    26821 aaggagtaaa taatggatag actatcttca cataatgcaa caaaggaagt agtacaaaaa
    26881 tataatttta aattttcaaa gtctttaggt caaaatttct tgatagatag taatataatt
    26941 gataaaatct tatctggagc tagaatcaca agaggagata atatcataga agtaggacct
    27001 ggtataggaa ctcttactcg tgagatgggt aaaatagcag aaaaagtagt ggctatagaa
    27061 atcgatagaa atttaattcc tatattgaaa gataccttgt cagatttaga taatacagag
    27121 gttgtaaatc aagatatact aaaagtagac atacaggaat tagtaaaaga taaattaaat
    27181 ggtggaccag ttaagcttgt agcaaatctt ccatattata taactactcc aatagttatg
    27241 aaatttttag aggaagacat acctgtaaca gacatagtag tcatggttca aaaagaagtt
    27301 gcagatagaa tgaatgctat tccgggtact aaagattatg gggcattatc tatagctgtt
    27361 caatactatt gtgatacaga gattgtggca aaagctccaa gacatatgtt tataccacaa
    27421 ccaaatgtag attccacagt tataggttta catgtaagag ataaaagaaa atatgatgtt
    27481 cataatgaag acatattttt taaaacagta aaagcatcct ttggacaaag aagaaaaact
    27541 cttcttaatt cgttgggagg tcttggtttt cttaataaag atgaaataag agaaatatta
    27601 aaagaagcta atatagacga aaaaagaagg ggtgaaactc ttagtataga agagttttca
    27661 gttctttcaa atataataaa tacaaaagta tcttctaaat agaaggtact ttttttaatt
    27721 ttgttaacat atattgttta gagaaactgt gttaaggggg gattgcagtg ggttctaaaa
    27781 gaaagtttaa aagagactat ataatactag aagctaaaga cataaacttt agatacaaag
    27841 aacgagtact gccaaaagct tttgcaaaag ttgaagtaaa tgatgaaaaa gcaattattg
    27901 cattatatgt agaaaatcta aaatatgtta aagatgggta taaagcagta gcaataaaag
    27961 atgaccatgg attaatagac ttaggaaata taattttaaa tgaacaagga agaggtgaat
    28021 ttgttttaga tttagaagat tctgatgatg agataaaagg tattgcatta ttgtatgaaa
    28081 gaaatatacc tttaattgga tttaagggaa ataagcttga aaattatgag gacatattat
    28141 ttcaagaggt agaggaagaa gaatatgaag aatatgaaga atatgaagaa tatgaagagt
    28201 tggaagaaga cgaagagata gaggataatg aggaaagtga tagagacgaa gatagtgaag
    28261 aagaatatat tatagaagaa tatgatgaag atgagtatga agactattgg gaagatgatg
    28321 aagatattga agaaggagag ttaaaagcaa gaacggaagt agaagattct ggtgatgagg
    28381 aaatagaaga gttcaataat tataaggaaa tagaaaatta taatagggtt aaagtacagg
    28441 aagaatatat agacatagaa tatgatgagg aagaagagga agaagaagaa gtttttgaag
    28501 taaatagaga agaagatagg tttgtttcct caaaacctac taaatcaaag aaagttcaaa
    28561 aagatcagaa taatattgaa aaaataaaaa gagctaatgg agtaagtcaa ggagagagtg
    28621 gaaataaaca aaccagtaca ttacttatgc caagacaaat aaaaaaaggt ttgaaattat
    28681 ttaaagaagt aaaacctttt gtaacagatt atatagataa gacaagatgg tggaaaatag
    28741 agataaatcc tacaacactg tgtggatata caatgcctta tttaggatat ttaaacgtat
    28801 tgaattacac tatgtatagt gatgcagttt tacattcata taaatacaga cactatttat
    28861 ttggtgttca gtatgatgaa tataataaga gaaaacatta tatttatgct atcccaggaa
    28921 atagaaatga acagccagac aatggaagca caggattttt aagatatcaa gcttgtgata
    28981 atagaacaaa tagtttagga tattggctat gttttataga ttctagacaa agaaatatag
    29041 ttaggtaaaa ataataaaaa tgaaaaaatt tagactcaat tattatttta ctgaaaaaat
    29101 taatgaaatg tagtacaaaa ctttaaaaac tattgataat atttaaatat tacactacaa
    29161 tatatcttga aatacctatt atattatgga ggaaaattat gataaacgag caaagaattt
    29221 taaatgagtt tcttgaatta gtacagatag atagtttatc tttaaaagag gggaatgttg
    29281 ctaaagtatt agttaaaaaa ttagaagaaa taggttgttc agtagtaata gacaatgctg
    29341 gtgaaaaagc aaatggagaa actggtaata taatagctac attaaaagga aataaagaag
    29401 gaaagaaaat attatttagt tcacatatgg atacagtaac tccaggtata ggggtaaaac
    29461 ctatagtgga tgaagcaaat ggaataataa aaagtgatgg tactacaata ttaggttctg
    29521 atgataaagc aggtatagca gctatattag aaggcttaag atatataaat gaaaataaca
    29581 tagaacatac tgatatacaa gttgtattct ctatatgtga ggaatgtgga ttagttggag
    29641 ctaaaaattt agactatgga aaaatagatt ctgaatatgc atttatatta gatagtggtg
    29701 gttctccagg tgaaataata gtaaaagctc ctgcacaaga tgtaataaat gttaagatat
    29761 taggaaagac tgctcatgca ggtcttgaac ctgaagctgg aataagtgct ataatggtag
    29821 ctgccagagc aatagaaaat atgaatttac ttagaataga cgaagaaaca actgctaaca
    29881 taggaattat aaacggtgga acagctacaa atatagtaac aggagaagtt aatatagttg
    29941 cagaagccag aagtttaaaa gaaaataaat tagatgttca aactaaacac atggtagaga
    30001 cttttgaaaa agctgcaaaa gattttggag ctcaaattga gatagatgtc aatagagcat
    30061 atacaccaat agatgttagt gaagattctg aaataataaa acttgcaaag aaggcttttt
    30121 caaacttagg tatagaaggt cacactgaat ctacaggagg aggtagcgat acaaatatat
    30181 taagtaagaa tggtatcgaa gctataactt taggaattgg tatgaaaaat gctcatacac
    30241 taagtgaaca tatagctata aaagacttat atgactctgc taaaatggta gtggagataa
    30301 taaaggaagc ataaatttaa ataatagtgt ataatatata tatcgcctag cttaagctag
    30361 gtgatttttc attttataga agattgataa tctctattga aagcaaagag tatacatttg
    30421 catataagag agtgtttaat ttatgttcag atgtaggttc ttaataatat ttagattgtt
    30481 tcataaggga ggaataaata tggaaacaag gtatgaagaa gcaaataaaa taacaataca
    30541 atcaatactt tggaatgtag tattaacaat aattaaggtt atagctggtg ttattggtaa
    30601 ttctagcgct atgattgcag atggattaca ttcagcatca gatattataa gttctatagg
    30661 agtactaata ggcaattatg tatcttctag acctggagat agagagcata attatggtca
    30721 tgagaaagca gagacattag tatcatttgt gttatcaata ttgcttattt tcgtttctat
    30781 aacaataggt atagaggcaa ttaaatcttt atttaactta gatgcattaa gtgttccatc
    30841 aatattacca ttagtagtat cagttatttc aatcctgata aaagagtatc aatatagaat
    30901 aacaataaaa gttgctaaaa agataaattc accagcctta aaagctgatg cttggcatca
    30961 taggtcagat gctttatctt cagtagctgc ttttataggt ataggtggtt ctattttagg
    31021 gtttaagcca ctagacccaa ttgcgtcaat tgtagtggct atatttgtag ctaaagtagg
    31081 aattagtata cttataagtt ctgttaatga attgatggat gtttcagttg acgaagaaga
    31141 gataaaagaa ttaaaattta ttgtagcaga tacagaaggt gttaaaaatc ttggtgatat
    31201 aaagactaga aaacatggag ctatggcata tgtagatttg actatatgtg tggatgaaaa
    31261 tttgacagtt aagcaaggtc atgatattgc taccaagctt gaaaaacata taataaaaca
    31321 tatggaattt gtaaaaggca taacagttca cgttgaacca tgtactaatt gccaaggaaa
    31381 taagtgtaat aattaattaa aacttaaaaa aaagtgtaaa aagttatata attgttttat
    31441 gattataaac tctaggggtg gttaaatgag caagaaaaga aaactaaaga aaaaagctgc
    31501 aatattaata ggagtagttg ttttctttat aatatacttt atatccttta gaataggaat
    31561 aaatatggaa aaggataaaa gtgaagtgcc aaagaaggta gaaaaagaag aagaagataa
    31621 taggtcttta aggactcaaa taaaagaaaa gaaaaaggtt tatatatcag acaaaaatat
    31681 agaaaacata aaaattgaag aagatatgtg ggatgaaata aagttatttt tctcagattt
    31741 taagaaagta agaaatacta cttcttctta cgaagcagtt tatgaaggtt attctgatga
    31801 tggagttaaa ttttctactg accttaactt ttttagagta tatactgtaa ataaagaaga
    31861 atattataaa gtaccagtta gttctaagga tgcttttaag aaacttttag atgagagtat
    31921 atatacttca tttgaccttt taagtcatta taaagattgg aaagaggtta ctataactca
    31981 tggaaaagaa attaaaaaag ttcatagatg gaaatttgat gatttagcac ataagatgat
    32041 ttcaaagagg gttgtaggaa aagttcaacc tgagaaaagt aaggaaagaa gtgactataa
    32101 ttttactata aatataaaag gtgataattt tgatgtaaaa gttgatacaa tgggaaaaga
    32161 ttatgtaaaa gttacttcta agaaaaatgt atcttactat gaggttcata caagtttatt
    32221 tgattacctt aaaaatgaga tatttgaaat tggaaagaaa taagacttta agaaggctat
    32281 caaattagat atttgatagc ctaaattatt ttatatatta tttttcaacc aacaagtctg
    32341 caaccttata aattggacca gcaccagcag ttattactaa atcattgtcc ttaacatttt
    32401 cacgtaagta ttttactata tcttcaaatt cttttatata gatggcatct acattgtttt
    32461 gatataattt ctcaaccaag tccttagaat gtatatctcc tgggtctttt tccctagcag
    32521 catatatatc tgttatgata actttatcag cagcatagaa tgcctctgaa aattcaccta
    32581 aaagagattt tgttctagta taagtatgtg gctggaagat acaccataaa gtggattttt
    32641 ttaatttttt ggcagcagct aaagttgctt ttaactcagt tggatgatgt gcataatcat
    32701 ctactactaa agcattctta tagtaccctt tagtttcaaa tcttcttccg acacctttat
    32761 aaatttttat attttttctt atagtctcta agtcaatacc agaaacaaga gctgccatta
    32821 tagcagaaga agcattgtat atgttatgaa gaccatatac agaaagttca aattctccta
    32881 aatctcttcc ttcatattct attctaaata ttccatgacc actattgtca aagtgaatat
    32941 cttttattac agcatcattg tcagaatctc tgccgtattt tataatagta gctttaacat
    33001 catacaatat gtcatcaata ttttcatcat cgccatttat tatgaaatag ccttctggag
    33061 gtaataattt tccaaatttg ttaaaagaag ccttgatttc atctattcca gagaaataat
    33121 caagatggtc ttcttcaaca tttaaaacta tagatatctt tgggttaaaa ttaaggaaac
    33181 tatctacata ttcacatgct tcagttataa agtggttgga attacctatc ttaacattac
    33241 cacctatcat acttaagtta ccaccaacta gtatagttgg gtctaagtct gcatattcaa
    33301 agattgtaga taacatagat gttgtagaag tttttccatg tgttccagaa actgctatag
    33361 aatttttata ttccctcatg atttggccta aaaaagtcgc tctgttcatt accaatttat
    33421 ttttttcttt agcagccaca agttcttcat tgtctggatg gactgctgct gtataaacaa
    33481 ccatatttac atcatctgat atattatctt ttttctgacc aatataaata gttgcccctt
    33541 ggtccctaag tttgtctaat aggtatgatt cgtttgaatc cgaacctgaa acttgataac
    33601 ctttattgat acatatttca gctaatgcac tcatgctgat accgccaatt cctataaagt
    33661 gtatattcat aataaaacca cctttctttt taattaagtc ctacaatatg aactatttat
    33721 gtggtataat aatataatgt tcaatatttt ataattaata tgcatataat attatatgta
    33781 ttttattttt gaatataata aaacataagt aatattatac cacaataaga attgttatgc
    33841 attagttagt ttaacgttat ataaaggtac ttgtaggagg aaataataat gaaatttaaa
    33901 agaacagaga gaattggagc aatagttaaa atactgtctg ataatccaaa taaaatatat
    33961 acattaagtt attttacaaa tcaatttaat gcagcaaaat caacaataag tgaagattta
    34021 ttagttgtaa aaaatgtatt tgagaagcta catttaggta aagttataac tatctcagga
    34081 gcagcaggag gagtaaaata tatacctaaa acttctatag cagaaaatgc agagttctta
    34141 atggaattat gtgagagaat atgtgacaag tctagaatac tatctggtgg ttttttatac
    34201 ttgattgacc taatttatga ccctacaata gctgctaaga taggaaagat attcgcatca
    34261 aatattgagt atgtagatgc agattatgtt gtgacaatgg aaacaaaagg tatacctatg
    34321 gcacttatga ctgcaaaagc tatgaattta cctctagtta taataagaaa agatataaag
    34381 gtatcagaag gtcctacact tagcatgaca tatgtgagtg gaaacagctc taaagttgaa
    34441 agtatgagtt tgccaagaaa agctcttaaa ccagatagta aagttataat tatagatgat
    34501 ttcatgaggg gtggaggtac tataaaagga atggtagacc ttatgaatga atttggtgca
    34561 gaggttatag gtactggagt attcatatct acaacgaatc cttcagaaaa aatggtaaaa
    34621 gattatattt cattgattca attggatgtt aatggagata aaatagtagt agaaccaaac
    34681 ttaaagactt ttaaagatga atatagaaat gaagatttag acgaagaaga agattcagaa
    34741 tttgaatttg agatagatga agattaataa aaaaaatatt tagaaaaata tgtaaaaata
    34801 aaaagaggat atccctagtt gttcatagaa ttatttaaaa aacagtttat attaatttat
    34861 tccagcgata ataattttaa tataaattaa tttctgtcaa aatcaaaggg ggatattttg
    34921 gtatgaagat aactgacgta agagtaagaa aattaacaga agaaggtaag atgaaatgta
    34981 tagtttcaat aactttcgat aatttgtttg tagtgcatga tataaaagtt atagaaggcc
    35041 ataatgggct atttatagca atgcctagca gaaaagtagg cgaaggaaat ttcagagata
    35101 tagctcatcc aataaatgca gaaatgagac aagttttaga agatgcagtt ttacaagcat
    35161 atcatgaagc attagttcaa tgggaagtag ctgctgaata ataaatatat aaaatggaga
    35221 gagcccgaac atttaggctc tttttaaatg tagaatttct attaaaatat gtacttttta
    35281 gtaaaaaagt gctatattat tagtgataat gtatatgttg tatacaaatt gttagataaa
    35341 tgtattataa tgtatattga ttaagagaat aatacgaata aaattaaatt agattgaatg
    35401 gagtgtatca atgaacttta aagctataat ccttgctgct ggcaaaggaa caagaatgaa
    35461 gtctaaatac ccaaaagtta tacataaagt atgtggaaaa gaaatggtta accatattat
    35521 agatgtttca aaaaaatcag gggtaaaaga tactgtcgtg attttaggac atgaagctga
    35581 ggtagttaaa gaaaagcttg cagaagaaat tataatagcc atgcaaacag aacaacttgg
    35641 gacaggacat gctgtaaaga tggctaaaga atatattaat gatgaagata caatagttgt
    35701 actttgtgga gatactccac ttataaaaga agagacactg aagagattat ttgaatatca
    35761 tatagaaaat aaatatcatg ctacagttct tacaacaaga gttggaaatc caacaggtta
    35821 tggtagaata ataagagata agaagggtga ccttcttaaa atagtggaac aaaaagatgc
    35881 aaattcagaa gaaaagatga taagtgagat aaactctgga atttattgtt ttaatggaaa
    35941 gagtcttaga gaagcactag atttgctaaa taataacaat tcacaaggtg aatattattt
    36001 aactgatact gctaaaataa tgagagataa aggattaaaa gttggtgcat ttgcaggttc
    36061 aactattgaa gaacttatgg gcgttaattc aagagtagaa ttatcaaagg cagaagaaat
    36121 tatgagacga agaataaatg aatctcatat ggtaaatgga gtaactataa tagacactaa
    36181 ctctacctat atagaatctg atgttatgat aggcaatgat actataatat atccaggtgt
    36241 tatgttacaa gggaaaacaa ggataggttc agattgtata attggaatga actcatctat
    36301 aacaaattca gaaataggtg atggtacaga aataaaaaat tcaactataa ttgatagtaa
    36361 ggttggagaa aattctaatg ttgggccata tgcatactta agaccaaaga gtgacttagg
    36421 aaataatgta aaaataggcg attttgtaga agtaaaaaat gctattatag aagatggatc
    36481 aaaagcatct cacctttctt atataggaga tgcacatgtc ggtaaaaatg taaatattgg
    36541 atgtggagta gtatttgtaa actatgatgg taaaaataaa tttaaatcag tagtaaaaga
    36601 caatgcgttt ataggttcaa attctaattt agttgcacca gtagttgtag aagaaaaagg
    36661 atatatagca acaggttcaa caataacaca tgatgtccca gatggtgctt tggcaatagc
    36721 aagagaaaga caagttatca aagaaggatg ggtagaaaaa aagaatcaaa aagacgacca
    36781 aagtaagtaa ttatgtagtt tattattttg gctaaaaaat ttagctcgaa attattataa
    36841 attatattca ttagtatttt aaaattttca ggagggttac ataaatgaat actagcggaa
    36901 gcgagattaa aattattgca ggtaattcat cgaaagagtt agcacaaaaa atagctgact
    36961 atataggtgt atcagtacta gattgtgaag taggtacatt tagtgatggt gaaatatgtg
    37021 taaacatgaa tgagacagta agaggttgtg atgtgtttgt agtgcaatct actaacagcc
    37081 cagtaaatga taacttaatg gagttattaa tcttaattga tgcgttaaag agagcatcag
    37141 caggtagaat aacagcagtt attccttact atggatatgc aagacaagac agaaaggcta
    37201 aggcaagaga tccaatcact gctaaattag ttgcaaattt aataactgct gctggagcag
    37261 acagagtatt aacaatggat ttacatgcag ctcaaataca aggatatttt gatataccat
    37321 tagaccactt actaggtgga acaatattag caaattattt taatgaaaag aaaatagaag
    37381 atttggtagt agtatctcct gacttaggaa gtgttactag atcaagaaaa tttgctaata
    37441 ctttaaatgg agaagttcca atagctataa tagataaaag aagaccgaaa gctaatgtat
    37501 gcgaagttat gaacttaata ggtgatgtta aaggtaaaaa tgttatacta ttagacgata
    37561 tgatagatac agcaggaaca atagttaatg ctgcaaatgc acttaaagag tttggagcaa
    37621 aagatgttta tgcttgttgt actcatggtg tgttatcagg tccagctatt gaaagaattg
    37681 ctaattcaga aataagtgag ttaatagttc ttgatactat acaacttcct gaagagaaaa
    37741 gaatagataa gataaagata aaaacagtag cccctttatt tggagatgct ataagaatga
    37801 tattctctaa tgaatcagta agtaaattat tctaatttat tgtatttatg agagttgttt
    37861 aaaaggatat aaaccttttg agcaactctt ttttgatttt atacttatgg aatgttattt
    37921 ttttcttgtt agaaaggtat atattattgt aaaaagagat tatagtttaa aattatgtat
    37981 atttaagtaa aataaactta ataaagggca tattattcaa aatattatga atataaaaaa
    38041 tattacaaaa aagtattgaa aaaattcaga ttatgtagta ttatgtaaat ataaataaat
    38101 aaataaagaa agaggtgttt ccaatgggaa ggttagaaga tgaaccccta ataattaaat
    38161 gattcagtca caatctaaag tgaatataaa aatctattga aagtttattt ataagaattg
    38221 aaaatagtat ctattctatc tttagtgttt gtgagagggt tctggattat ataagattac
    38281 tgtaaagagt aattttgcac aataagcata tctgtaaatg aagagtttcg tttatataat
    38341 gattgtggct gaatcataac tataatagat agaatgttta taatagatga ttttataaaa
    38401 tactatattg taatagcttt tagctttcaa ataaatatta gcaaaggatg gaaatgacaa
    38461 tgataaaact aaatgataat ttataaatat ctccttacga tatataataa ttgtagggag
    38521 atgtttcttt tttttgtata gtataatttt tctagaaatt ctgtttcaat atgtaaaaag
    38581 ttggtatata taaatagtat aaacagtgtt gctaaaatat ggtagatatt atataatata
    38641 agtggatatg tatatacatt atgagttata taattttgaa tttaataaaa tagaaacgtt
    38701 gatttatgtt ctgtaatgtg ggcaccttag agcatattga gttagtggtg caaccggcta
    38761 tgaaattgta tttatttata gatactatta ttttcatagc tttttttatt taaaaaatgg
    38821 ttatgtgtta gaaataaatt tggttagtac gtttaaataa ttttacttag atttttaacc
    38881 agatatatta taagtaagta ttaattaaaa aatttaaggg ggaataaaaa tgaagttaaa
    38941 aaagaataaa aaaggtttca ctttagtgga attattggta gtaattgcaa ttataggtat
    39001 attagcagta gtggcagttc cagctttatt tagtaatata aacaaggcta aggtagcaag
    39061 tgttgagtct gattatagtt cagttaagag tgcagcatta tcttattatt cagatactaa
    39121 taagatacca gttacaccag atggtcaaac tggtttaagt gttttagaga cttatatgga
    39181 gtctctgcct gataaagctg atataggtgg aaaatataaa ttgattaaag ttggtaataa
    39241 attggtatta cagataggta caaatgatga aggagttaca ttaacagaag cacaatcagc
    39301 aaaattattg agtgatatag gtaaagataa aatatataca ggtgttacag gagataattt
    39361 tggagaccaa ttaacaaata ctacaaaaat agataataaa gctctatata tagtacttat
    39421 agataatact gtgatggact caacaaaata attaaaacta tatttttata aagaatattg
    39481 taaatttaat gaaaaatata atataaaaga caggaagaaa atcttcctgt ttttttatac
    39541 tattttcttt aatgttcaat tatgaatgat gatataattg agatagtaaa ggagtgaaac
    39601 ctgtggctaa aaaagttaga ataggagaca aactggtcga aaaaggatat ataacagaag
    39661 accagcttaa atgggcacta tcagaacaaa aaaacagtgg aaaaagacta ggagaatttc
    39721 tagtacaaga agggcttata gatagtaatt tactaataag tgtattaaaa gaactcttgg
    39781 atatagaaag tatattttta gaagggacag aaatagacac tttagctaca aagatggttc
    39841 cagaaaatat atgcaaaaga tatactgtat ttccatttaa aattgatgga aataaaatat
    39901 gtttagccat gtcagaccca caagacagag aagcagttca agatgtaagg cgtatgtctg
    39961 gtaaagacgt agagatattt atatcaagta cagaagatat aaacaaagca ataggtcatg
    40021 cttatgcaca ttcagaaata aataaggcaa tgactgagta caacaaaaat agaactggtg
    40081 gagtaagaga aacagtaata cttgaagaag atgtaaatgc tgctccaata gtacgattag
    40141 taaataacat actagaaaat gctgttagaa tggaagcaag tgatatacat atagaacaaa
    40201 gtgaaaatta catgcgtgtt aggtttagga tagatggaat gttaagagaa tatatgagga
    40261 tgaactcagc accatataag gcagtaatca gccgtatcaa gataatgtca gatataaata
    40321 tatctgaaaa gagaatacca caggatggta gaatctattt aaaagtagat aataaaccca
    40381 tagattttag agtttctaca atgccaacta acagggatga aaagatagct atgagggttc
    40441 ttgataagag taattttatg gttagtaaag aagtactagg aatagacgaa catggctcta
    40501 agatatatga tgaattgata aacactcctt atggtcttat attggttgtt ggccctactg
    40561 gaagtgggaa aaccactaca ttgtattcaa tgttaaatca actaaataca gaaaatagaa
    40621 atctattaac aatagaagac cctatagagt atgaattacc tggtgtaaat caatctcaaa
    40681 taaatgaaaa ggcagggctt actttcgcca gcggacttag agcttttatg cgtcaagacc
    40741 cagatataat aatggttgga gagataagag atactgagac agcagaaata gcaattagag
    40801 cttctcttac aggacattta gttttaagta cattacatgc aaatacagca gttggagcaa
    40861 tttcacgtct tttagatatg gatgtggaaa gttttttaat aacttcatct gttttaggtg
    40921 taatatctca aagacttaca cgaaaaatat gtgagcattg taaggtttca tatgaagcag
    40981 atattggaga aaaaaaggct cttggtattg atgtaaatga atcagtaact atttatagag
    41041 gaaaaggttg tgaaaggtgt aataatactg gatataaagg acgtctaggt atatttgaaa
    41101 tgcttgaaat tactccagaa ataaaagagt taatagattc atctgcaaat caaagagaaa
    41161 ttttaaagat ggctagaaaa caaggtatgg ttagcttaaa agaggatata gttaaaaagg
    41221 ttttaaatgg aaagacaaca gtagaagaaa tgattagaat aattttgatg actgattaaa
    41281 ggatgatatt atgaaaagtt ttaaatacac agtaataaaa gaggacggaa aaaagcaaac
    41341 tgatgtgatt gaagccaacg attttaatga agctagaaat cttcttagaa agagaaatct
    41401 tagagttatt gaaatcaaag aaagcaaaaa taaaaatata agattatcta gtagaaagag
    41461 aaaaaaagac ttgggagctg accagataag ccacttttgt agacagtttg ctattatagt
    41521 atcttctggt ataaatagta tttcaggatt agaaacatta gctagaaggt caactaacat
    41581 tacattaaga gaagaaatta atcgtatagt ggcagaaata aaagtaggtt ctactattgc
    41641 agattcaatg ctttcatcaa aatcaaagtt tccaaagtta cttggtgcta tggtagctac
    41701 aggtgaagct acaggtaaat tagatgaagt attaaaaagt atggcttcat tttatgcaag
    41761 tgaacacagg gttaaacaaa agcttagaaa tgctgcaaca tatccattaa tagttttgat
    41821 ttcttcattt ataatgattt ttatatttac aacatttatg gtgcctaaga tgattaattc
    41881 aattacaaca gtaggagcaa ctcttccact tataacaaga attgttatgg ggtttggtat
    41941 gtttatgaag aagttttgga taatagtact tttagttatt atattattta tttatcagtt
    42001 taaaaaatat ttaaaaacgt cagttggaag ggctcataaa gatagagtta taaacaagat
    42061 acctgtttta ggaaaaggaa taaattgtat ggtagctaca cgattttcaa gagcattgta
    42121 tctatttgta tcaacaggat acccattagt tcaagggctt gattatatta tagatagtgt
    42181 aaataacacc atggcagaga agattttagc atcagctaaa gatggaataa caagaggaga
    42241 aggcttagca gaaaatttag agagatatac gtattttgac tctgtgttgg tacagatgat
    42301 agctataggg gagcagacag gggaattaga gaatataagt agacagatgg cagaatttta
    42361 tgagtatgaa tccgagattt atttaaatag gatggcctca atgatagagc ctgttttaat
    42421 aattgcagtt ggtattatag ttgcgatact ggttgtatca atatttatgc caatgcttag
    42481 tatatatgat gccatgtagg agggaaagga caaatgaaca aggtttatgt atcatattat
    42541 ggcgattcta tttccatagt tgagggcaga tataaacacg ataaggataa gttttatgta
    42601 aaaaatttta atgtgttttc aatagaggat attgcacaag atttttctaa ggaaaagtat
    42661 gctctattga gatacgcatt agaaaatgtt aagttaaaat caagacatgt agttttttgt
    42721 ttaaatacaa gagatgtaat tttaaaaccc caaaaacttc ctaatatgga caaaaaggat
    42781 ttagatggat ttatgaagct agagatggac gaaatgatgg ctttggagtc agatgaatat
    42841 gtattttcgt atgaagtatc tagtgaaaca cctgataatt cagatggcga tgaatcaagc
    42901 ttaaatctta tcattggagc tatacaaaag gaagaggtaa atgcaattgt agagataatg
    42961 catgaatttg atttagtatt agatagaata gatacattat caacagctta cttaagaatg
    43021 cttaaaaatt tagactacaa tgatataatg gtaaccaata taagtgacaa tagtacaatt
    43081 ataaatatat ataagaaaga tactttattt attagtgata atatacctat aaagataact
    43141 gctaaagata tggacatgca attattaaat gtagtagaag aatcaaaagg tcttatgaat
    43201 tactattcgt caagaaactt tggtaaggtt acggatacta tattaatatt aggaaaaaga
    43261 tattccaata aattaattta tgaaactttt agctctgcat tttcaagcta tgtttctcaa
    43321 ggccttactg agataatgga tatatctgat atgataactg gagatataga tgaagatgat
    43381 ataaattcaa ttgtagagct tttaggaagt atgatagaac ctaaagggaa aagagatttt
    43441 gaaaatataa actttttacc aatggatata cttagaaaac agataaaagc taaacaaatg
    43501 aaaaacatac tgaaaattgc tccaatagtt attttgattc ttgctatacc ttatttatgt
    43561 ttaatttttt caaataattt agcaaataag gaacttgaaa atgttaatgg tgaaataaga
    43621 aatattgaat ctgcatatta tcagattgga aatatagaaa aaatgataca gagtaaaagc
    43681 gaagaaataa aggtatatga tatgttaatt gggaaaaagg taaagtggga aaatttattg
    43741 gatgatatag ataaaaatac tccaagtaaa gttgaactaa caagtttatc aacaacttat
    43801 caaaatcttg gaactaataa taaagctgat aattcaaaaa gtaataagac tacaacagat
    43861 aaatcaagta acaatgaaac aaaatcaagt acgaaaagtg atagtaatgg agataaaaca
    43921 gataatgatt taaatgaaga taagactaca aatgtgtcag aagcattaac tggaaatagt
    43981 gagactaata gtaataacac ggataaagat gataaaactc cattgtatga taagatacca
    44041 aatgttataa atatagaagg aaatgctaaa gattcctctt atgtaggtca atttttatat
    44101 aaattaaagg gattatacta tttcaaggat gttaaattac atagcataaa aagtaatgca
    44161 gaagattcta actatacatt tagtatgaca ttatacctga aagaaggtgt attaactaat
    44221 gaataaagat atatttaaaa aagatataaa agatatattt aaaatggaag ttagtctaaa
    44281 agggattctt ataaaggtta taattttatt agctatttta tcatatggtt attttggact
    44341 ttaccctcaa tatcagaaat atattgctac aaaaaattct gtaaaacagg ctactgaaaa
    44401 attaaatata tataaagaga aaactgcact tatgccaaaa tatgaaaaac aacttgaaga
    44461 agttgaaagt gaattaaaag aaaaaagcaa aaatctttta tatgatatgc aagatggtct
    44521 ttttttaata ggtttagata aaaaaatgaa ggcttataat attgacttaa ctagttatga
    44581 cgttggaaat gttaaagaat acgaacattt ttatggtata tcaacaacaa taagtgttag
    44641 aggtgattat agaaatgtca aaaaattaat ggcttattta gaagaacaaa aaaatgttac
    44701 tcaaatacta gattatacaa tgacttcata tatagaacca gaaaaagaag aggaagaaac
    44761 aacaaacaat aaggatttaa ttaaaaatgt gaacataaat aaagatacaa aaatatactg
    44821 ggtggaaggc gaaaataagt ggcatttata taaggattgt ccattgataa aagagggaga
    44881 gattctaaaa aatgacaaac ttttagatag gtctactaat tatctatgta atacttgtgt
    44941 acttagagct gcaacagaaa aagaagcaaa aaaagaagtc gtagctccaa aggcagaagg
    45001 tgtagtagat gctacattta aatttataat gtacactaaa gagaatacta caatgatact
    45061 tgatacagat aatccatctt catggagacc aggaaaatat aatccattta agtctagtgc
    45121 gaaataaagc taagtaagct ttaaagatag gtgatgagtt tgtacaaaaa taatgaaaaa
    45181 ggtcttactt tattagaagt aataatagct gtttttatac tgacaatagt tttaagtatt
    45241 tcttataaag tgttcaatgg tataacatca gcagtaaaaa agcaacagat tattacagat
    45301 gctcaagtaa atattaatct aattaataag tatctaaata gagatttgga aaactgtaaa
    45361 gagctaacta aaactggttc aggtaataat tatgaataca atatagagat gccagataat
    45421 gttgtaaaat atgaagtttc tatagaaact aaaaaaaata cagaggtata ttctgtaacg
    45481 agaatccaaa acaatacaat tgatacagaa aatgaagtta gagaagagat aatctataat
    45541 caaccactag ttcaaaacaa taaagaaatg aaggaaacac catttaaaat agaaaagcaa
    45601 actggtaaat ctatttatac tgtaagtata tactataatg aatcagtgca agaaagtcat
    45661 aaaaatagca atttaaataa caaaacttat acatttgatg ttatgtcaag aatagggtaa
    45721 taagaattta ttaaaaaata agtaggttga taaaatatga gtaaaaagaa tagtgaaaga
    45781 ggattttcct taattgaagt gttagtagct atggctatta tgggaattgt actatttgca
    45841 ttttttaata ttatcaatac taataacaaa gcaaacacta aaaatgacac agatataact
    45901 tccttaaact atgtccaaag tgaaatagaa aatctaagag aaaagataaa aagtggagaa
    45961 tttgattttg atagtttaga taaactagaa gatggaactg tcgtatatga aaaattaata
    46021 gataaatcaa aaaaagttgt atatgataaa gttcttagtg aaggtgacgt gagcttatat
    46081 gatactccat atgaaaagat tacaacaata aaagatgaag atggtaattt aatcgacaaa
    46141 ggaaatatta caaataagat aaagactatt gtagaagata aaagtggtca gatatataaa
    46201 atagctgtaa ctgggaaaag catgaatgac tattcaagta aaaaagaggt taaaattata
    46261 actgaaatat ttaaagataa ataattttac ttgggggtga ggttttgagg aagtggaata
    46321 aatttaaaag tgaaagaggg gcagctttag ttttagtttt gattgtagta gcattgcttt
    46381 ctattgttgg attgatattt tcaaatcaga tagctaatag aataaaatct acaaagacta
    46441 ctaatgaagg tatacaagca aagtatttag cagagacatg tgtggaaaat agtattgata
    46501 aagcatatga aaaattgtat gatgagcttg agaaaatgga taatgagttt aaaagtgaaa
    46561 atcaagaaaa atccatatct aggtcaaaat taagaaatat atcagatgaa gattttaata
    46621 atcaagatga ggaaaatatt gaagtagaaa gacttggata tatgaataat ataaatttct
    46681 atttaaataa agcttcttca gacttggaaa aagctagtat ggaattgaaa aagctatatg
    46741 atttagatat gttggactat agagacattg aatatgtaga tgcaaatatt atttcacata
    46801 gagattctat cttagaaatt tgcaagaatt atacttctgg agatattagt aaaataaatg
    46861 aatatattct gaaagaagat atagactcaa ctacattgat tgaggcaaag ttagtgaata
    46921 atgatattct tttaaaaatg tttttagaag aaaataaaat tgaaaatgaa catttaaatt
    46981 cagccttttc acatacttat aaggcattag ataacatttc tttggcgatg caaaatatga
    47041 ttgagtatag acatacgttt catatagatg agccaaaagt agaagtatct aatgggattc
    47101 cagactctca acaatattat gaactaatac aaaatcctat aataaatagt atggagtata
    47161 tctggaatag taaatgggat acattagaaa aactattgga aattttacca aatcaaactc
    47221 aaggatttaa ttctttaaga gttcatttga gaaataatgt aagaaaattt gagaagttaa
    47281 gcgataatat atctagtggt aaaaaaaata cagcaaaaaa tttcttaaag tataaagagt
    47341 tattgtatga aatatcagac caatgtaatc aactaaaaag tatgtcttat gagaaaatac
    47401 ctgttaaata tgataacatg gctttgataa caacttttga ctatatacaa aatgagcttt
    47461 tagcagagat aaaatgcaga ttaaaagaat taaaaccaca agaaattgat aaaacagaag
    47521 gtattactat aaaaatacct ttttataagg ctgactacga catgacaaaa gaaggatggc
    47581 ctaaattaaa agaaaatggt tcaggggcgg agttaagctt aatggtaact ggtgataaag
    47641 atggaataaa agaagtagaa gttacagatg gtaaaaaaaa tattattggt ttaggtgttg
    47701 aagaaaattc aaattcaaag tataaggttg acaccattgt aaactttaat ctaaatatag
    47761 atacaaatgt agttggaaat tatgatataa aagataaaat tttgattaat catgatataa
    47821 gttcatacaa aaaagtaaac taaatataag aagcaactta gtataaataa ataataaaat
    47881 aattttatta tttactacta aaaaaataag taaactaata gaagatatgg agagtaaata
    47941 ttatgtatat ttatgattta ttagagcaag gtataagact aaacgcatca gatatacaca
    48001 taacagttgg aacaaatcct gtagctagag taaaaggtgg atttgtaaaa ctaagtgaac
    48061 aaatattgac atcagaagta acaatgcaaa tggcaaaaga catagcgggg gaatctatgt
    48121 ttacagtaat agaagaacat ggagaagctg atttttcagc ttctctaaaa acaggagaaa
    48181 gatttagggt aaatgcatat aggcaaaaag gaaattacgc aatagcaata aggactataa
    48241 cagcagaaat tccaacattt gaaaaattag gccttccaga gagtataaaa tcttttactg
    48301 aaaagcataa aggattagtt ttagttacag gtccaacagg aagtggtaaa agtacaacac
    48361 ttgcaagtat gataaatata ataaatgaaa aacaacaaaa acatataatt acacttgaag
    48421 acccgataga atatgtacat catcataaac aaagtttagt aaatcaaaga gaagtaggaa
    48481 ctgatacaga aagttttcat tcagccctta gagctatttt gcgtcaggac ccagatgtaa
    48541 tactaatagg agagatgaga gaccctgaaa ctgtttcaat agcattaaca gcagcagaaa
    48601 caggtcattt agtattttca acactacata cagtaggggc agctaagaca attgatagaa
    48661 tagtagacat gtttcaacca tcccaacagc aacaaataaa aacacagtta tctacagttt
    48721 gtgaaggtgt ggtatcacag cagttacttc ctacagcaga tgggaaaggc agaatagcag
    48781 caattgaatt gatgtttgct actccagcaa taaaaaacct gataagggaa ggcaaaacat
    48841 atcaaattcc aaacatgata caaactggag ttaaagtagg tatgaaaact atggaccaag
    48901 atttaatgga actttataaa aatggaaaga ttacaaaaga tatggcactt agtaggtgta
    48961 ctgaccaaga gtttatgaca agaatgatag gtggagtaaa ctacaatgga tattataatc
    49021 gttaatctat atgtatttat agtgggtata gtgtttggaa gtttctttaa cgtctgtatt
    49081 tttaggattc cagaaggtat atctatttct agacctcctt cccattgtat gagttgtaat
    49141 actagactaa agccaataga cttaatacca gtgctaagct atttaatgag tggcagaaag
    49201 tgtagatatt gttatgagaa aatttctagt agatatgcta tagtggaatt aattacagga
    49261 attttatttt taacagtatt tatgttatat ggaatatcta catcaactat ttattatttg
    49321 gttcttgtgt ctttactgat tataattaca tttatagata ttgaccactt tataatacca
    49381 gataacatat tgatttttgg agctatattt tctatgattt ttaacctttt atttaacgaa
    49441 attccagtta agaattcaat tctaggtgtt tttatttgtg gaggaagtgt ctggattata
    49501 gtttttttga ttgaatttgt aataaaaaaa gagtgtatgg gtggaggaga tatcaaacta
    49561 tttgcaatgc taggtcttta catgggtgtt aaaaatggtc ttttgacagc cttactaagc
    49621 gtttatgtgg gagcagtcta tggaatctgt gtaataatta taagtagaat aaaaggaaag
    49681 gaatataatt ctgttatacc atatggacct tttatatcta ttggagcatt aataacaatc
    49741 ttatgtggaa agcaattact tgaactttat ttttctatgg ttatatagat gatagtcaag
    49801 ttaaataaag ttttaattta aaaaaatgaa ttaaagtatt taataaggac aatattatta
    49861 ttaaccctat tactaaagtg ctacaaacta tggagtatat aataataatt tccttatttt
    49921 ttgcacattt gataaataaa tctctatgtg ttttttgtga tagagaaaag aaaaatttat
    49981 ataatacgtt ttttatttac ataataactg tagttttatc tgtattaata tatctaaaat
    50041 ttgggattag tgtagaatgt gtacaatata tggttttaat tccattttta ataattatat
    50101 ccattgtaga ttactacaca atatatgtat atgatataac aatagttagt ggtataatag
    50161 ttcaaggtat aatttttttg gtctttttca atatagctca atttgattat ataaatcata
    50221 tatttggact attgataggc tttattatac cttatattat tgctaaacta acaaaaggat
    50281 taggctatgg agatgtaggt ctctatagct tatgttgctt tgcattggga aataattatg
    50341 ggtcttatgt gatagtttta tcatttattt tagcgttttt gttttttatt attttataca
    50401 taactaaaat atttaaagat gtagatataa gaaagcaaat tccttttaca ccttttattt
    50461 ccttgtcaac aattttaata atatttacag agtataatat atttaatttt tattataatt
    50521 tgttatacaa atttatataa caggaggtaa gaaatgtacg tagtagtagg gttaggtaat
    50581 ccaggaaaga agtatgagaa gactagacat aacgttggat ttgatgttat agatattctt
    50641 gctaaagaat acaatattag tgttactaaa ataaagcata aagctttgat tggtgaaggg
    50701 agagtaggta ctgaaaaagt attattagtt aaaccacaaa cttatatgaa tttaagtgga
    50761 gaaacattaa tagatatata taaatattat aaggttgatt taagtaatat agtagtagta
    50821 tatgatgata tagatttaga agttggaaag atacgtataa gaaaaaaagg aagtggagga
    50881 actcataatg gcatgaaatc tataactaag tgcctaggtt caaatgactt tccaagagta
    50941 agagtaggtg tatctaaacc agaagctggt caagacttag cagactttgt actttctaga
    51001 tttagaaaag aagaatctga taacataaat gaagcattag aaaaagcggc atatgctatt
    51061 gactcaataa taagagaaaa tatagatatg tctatgaaca aatacaatgg atagtgagag
    51121 ggagatttaa atgaatgatg tttttttata tcctttgcaa aattcaaaag agtataaaga
    51181 tataataaac tgtataaaaa atacaaaagg ctcattattg gttaatggac ttttaccagt
    51241 acaaaaacct catatatcgt attctatatt taatgattta tcacgacaaa tgatttttat
    51301 aacgagtagt gatttagaag caaagaaagt atacgaagat ttaagttttt atatggaaga
    51361 taaagttgaa tatttaggtt ttcaagatat ttatttttat cacttggatg caaaggacag
    51421 aaacgaagaa gcaaagaaat taaaagtatt gttaaaacta gcaaataaag aaaaaatcat
    51481 tttagtaact tctattgagg cagttttaag aaaatacata ccaaaacaag ttttgctcga
    51541 tagtgtatct cattataagg tgggagatag cttagactta gaaaagttaa ctgagaaatt
    51601 agtttcattg ggatatgaaa gagtttcaaa aatagagggg tttggtcaat ttagtataag
    51661 aggtggaatt attgatgtat tttcacttga atatacaaat ccaattcgta tggaattatt
    51721 tgatgatgag atagattcca tacgaacttt tgacgtatat tcacaaaaat caattgataa
    51781 attgcaacaa ttctctataa ctccatctag ggaatttatt tatcccgaaa aaactacaga
    51841 tgcattagtt aaattaaaaa aagaaacaac taaaaatact gatgaaggta catttcaaaa
    51901 tatagattat atatcgagta agacttattt tgaaggtgta gagaactata tagattatat
    51961 ttatccagaa gaaaacaaaa gtatatttac ttatttagca gatgatgcaa tagtatttat
    52021 taatgatata acgagactta aagaaagatg cgaaaattat ataaatgagt ttagagaaaa
    52081 ttataaatta aatcttgaaa gaggtctggc tattaaaaac caaggtaaat tgttatatca
    52141 ctatacagat ttagagtact tagtaaaaga caagtctgtg gtattaaact cgctattgcc
    52201 aaagtctata aataactttt ctataaaatc tataataaat tttgaaagta gagaagttcc
    52261 tacatttaat ggaaaggtag atttgcttgt agaagaatta aatcggctga aatataatgg
    52321 atacaaaata attttagcaa caaatacctt agaaagagca aataaattag gaaaagattt
    52381 attggacaaa ggcttagaaa cgaccatttc taaagataga gatattgaaa ttaaatcttc
    52441 acaagttata attgtacctg cacacataaa cagtggtttt cagtataaat ctataaagtt
    52501 tgttgttata acagataacg aaatgatagg tgtttataaa agagcgtcta agactagcaa
    52561 taaaaaagtt aaaaagggaa agaaaataga atccttttta gatttaagtg ttggagacta
    52621 tgtagttcat gaaaatagtg gtgtaggtag atacacagga attgaacaaa ttacagtcaa
    52681 tgctattaaa aaagattata tgaaaatagt atatcaaggt ggagataatc tatatgtgcc
    52741 aatagaccag atggacaaag tacaaaaata tattggtgca gaagtagaaa aagttaagtt
    52801 aaataagctt ggaacaaatg agtggacgaa agcaaaagca aaagttaaaa aagaaattga
    52861 agatatgaca aaagacttga ttgagcttta tgcaaaacgt gaaaaaatac aagggtataa
    52921 gttttcaaaa gatacacctt ggcaggcaga gtttgaatcg ttgtttccat atcaagaaac
    52981 agaagaccaa ttaaaggcta tagaagaaac taaaaaagat atggaatcaa gtaaagtaat
    53041 ggataggcta gtatgtggag atgttggtta tggaaaaaca gaggtagcta ttagaagtat
    53101 ttttaaagct tgtatggacc aaaaacaagt tgctgtattg gttccaacaa caatattggc
    53161 ccaacaacat tataatacat tcaaagagag gtttgaaaat tatcctttga gagtagaagt
    53221 tttaagtaga tttaaaacac caaaacaaca aaaacagatt attgaagatg ctaaaaaagg
    53281 attagtagat attttgattg gaacacatag aataatatcc aaagatataa atttaccaaa
    53341 cttaggtctt gtagtcattg atgaagaaca aagatttgga gtaaaacata aagaagcttt
    53401 aaagaaaatt aaatctacag tagatgtact tacactttca gcaactccta taccaagaac
    53461 attacatatg tctttaagtg gaataagaga catgagtgtt atagaagaac ctccacaaga
    53521 aagacatcct gtaataacat atgttacaga gagtaaggaa agcgtaattc aagatgagat
    53581 agagagagaa ttaagtagag gtggacaggt attttttgta tacaatagag ttgaacacat
    53641 tgaagaaatg gcaagtatga ttcaaaaact cgtaccagat gctagagtgg ctgttgcaca
    53701 tggaagaatg acttctaaat cattagaaaa tataatccta ggatttttaa ataaagatta
    53761 tgatgtacta gtctgtacta caataattga aactggtatg gacatatcaa atgcaaatac
    53821 aatgattata tatgatgcag ataaaatggg attggctcaa ctttaccaat tgagaggtag
    53881 ggttggaaga agttcaagac aaggatatgc atatcttttg tatgaaaaag ataaaacttt
    53941 aagtgagata gcagagaaga gattaaaagc tatcagagaa tttacagagt ttggttctgg
    54001 ttttaaaata gcaatgagag accttgaaat aagaggagca ggaaatattt taggttctca
    54061 acaacatggt catatggcag ttataggtta tgatttgtac gttaaaatgc ttaatgatgc
    54121 aattaaaaaa gtcaaaggtg aacctattgt ggaggaaatt gatgttgaga tagatttaag
    54181 tgtaaatgca tacattccag ataattatat caaagatgag ttgattaaaa ttgaaatgta
    54241 taagaaaata gcttctattg aaaacaaaga agacatgttg gatatacaag aagaacttga
    54301 ggatagattc tctgatatac ctaaaccagt ccagacactt cttacaatag cttatataaa
    54361 atcgttatgt aagatattaa aaatagaaaa gataagacaa ttaaaagatg aaatattatt
    54421 agttccaata acaaagtata gaactaaaca gaaaataggt tataatatag ttacagaatt
    54481 agaagaatta ttagaaaaga tgtgcaaggt aaaataactt gtaaatttaa gaagggatgt
    54541 tttaaatttg aaaaaagtaa taacattggt aatagctatg attttggtag tatctgtgac
    54601 tgcttgcagt tctagtaaag gagaaactgt ggcaacagtt gaaggtacaa agatatcatc
    54661 agatgaattt aaaaaaacta tagctcttta taaagattct atggaacaaa cttatggaaa
    54721 agatatatgg gataaggaag ttgaaaaggg tgtaaaatac aaggacaagt ttaaagattt
    54781 aattcttgac caacttataa ctacagaagt aatatattct caagctaaaa aagataactt
    54841 acttcctaaa aaagaggatg ttgaaaaaag ttttaaagaa ttaaaagacg ctatgggtaa
    54901 agatgaaaaa tataaagaac aacttaagaa attaggtata gatgatgagt ttttaagaga
    54961 ccaacaagag aaagatttag caatgcaaaa ctatcaaagt aactttgcta aaaagactaa
    55021 aatatcagat gaagaaatga aaaaatacta tgatacacat aaagatgaat ttaaaaaaga
    55081 tgaggtagaa gcttctcata ttttattgaa aacagtagat gataataaca agccactttc
    55141 agataaggaa aaagctgaag ctaagaaaaa ggctgaagag gctcttaaag aagttaaatc
    55201 aggtgaggat tttgcaaaag tagcaaaaaa atattcacaa gatacttcag caagtgatgg
    55261 tggtaaatta ggattctttt caaggggtca aatggttgct gaatttgaag atgctgcttt
    55321 ttctatgaaa aagggtgaag tatctgattt agttgaaact caatatggat accacataat
    55381 taaagtgaca gacagaataa atgagcaaac atcatttgaa gatgctaaag aaactataaa
    55441 agaccaactg ttgaaaaata aatatcaaga acaaatagaa aaattaacta aagaagctaa
    55501 ggtagaaaaa gatgaaaaag taataaataa aatcacaatc taagacttaa aaaaagagta
    55561 atatgcttaa aaaagctata tctggataag atatagcttt ttttgtatat ttttcttaac
    55621 aatggtaaaa ataaacttaa agtaatttat ggagggatta aaaaatatga aagcaacagg
    55681 tatagttaga agaatagatg atcttggaag ggtagttatc ccaaaagaga taagaaagac
    55741 attaagaatt agagaaggag accctttaga gatattcaca gcaaaagatg gagaagtcat
    55801 acttaaaaaa tactctccaa taggtgaatt aaatgaattt tcgcaagaat atgctgaaac
    55861 attagctgaa gtactaggat atggagtgtt gataacagac ttagattcta taatagctgt
    55921 atctaagctt cctaaaaaag attataaaga aaaaagtata agtgatgagt tagaagcaat
    55981 aataagtgaa agaacagtaa aatattcaaa agataaaaac attttaccat tattcaagga
    56041 agaccaaaaa gaatatacta gtcaagttat catgcctata attagtgcat ctggtgactg
    56101 tataggttca attgtagttg tttcaaagga taaagataca attgcagaaa gtgaagaaaa
    56161 atctttaaaa attgctgcta actttttagg aaaacaagtt caataatttt atcataaaga
    56221 ccttttacat gaaggtcttt tgaagttttt gtgtaaaata ttgaatatag cattaaaaat
    56281 atggtatatt aaagtttgtt atataaacag tatggaggtt atgttatgaa caataacaaa
    56341 aataaagact cctttctaaa aggagccctt atacttgggc tagcaggtgt aatcgtaaaa
    56401 ataatgggtg gattttttag gattcccctt ggaaacatga ttggttcaga aggaatggga
    56461 tactatcagg ctgcttatcc tgtgtatact ctatttttaa cattagctac tgctggattt
    56521 ccaacagctg tggcaaaatt ggtttcggaa aaagttgcaa ttggaaattt taaaggtgca
    56581 aataagatat ttaaggtatc acatacagtt ttattcatta ccggtataat atcattttgt
    56641 atattatttt ttggagccga ctacatagta acaaacgtaa tgaaaaatcc aggtgcgtta
    56701 tactctatga aagccattgc tccagcatta ctatttgttc ctgcaatgtc tgcatataga
    56761 ggatattttc aggggagaca agatatgact aagattgctg tgtctcaagt tgcagagcaa
    56821 ttttttagag ttgtattagg tcttactttg gcttacttgc ttatgaagag tctaggtcag
    56881 acttttggtg cagcaggtgc tatatcaggg gctacaatag gttcaatagc atctatgctt
    56941 tatttggtgt ttgcttatat gttagggaga aaagagcgta gagcagagat agatgcaagc
    57001 caaagattta aagatgaaag agtgtcttat atttttaaga agcttttaac tgttgccatt
    57061 cctataacaa taggagcatc agtaatgcca cttgtaaata tgatagataa tgttattgta
    57121 ataagaagac ttatggaagc aggctttaca tacaaagtgg caaattcaat gtttggtcaa
    57181 ttaacaggta tggcaatggc cacaataaat ttaccagcag tcataacaac tgcaatgagt
    57241 atgagcttag ttccagcaat ttctaaagca tatgcattag gaaataagtc aaaagctaga
    57301 aaagatacta agagtgcagt taaggtaact ttacttatag tattgccttg tgcgtttggt
    57361 atggcttctt tagcaatacc aataatgggt cttttatttc cacatgaacc atcttctgta
    57421 ggaactattt tgtttactct tactccatgt gtattatttt taggattaat acagacattg
    57481 actggtataa ttcaaggaat gggaaaacca atagtacctg taattgcttt atgtgttggt
    57541 atgctatgta aaattgtaat aagttatact ttaacaggta taccagatat taatgtactg
    57601 ggttcagcat ttggtacagt tacagcatac tttgtggcag ccatgattaa cttactatat
    57661 gttaaaaaac acatgaatgt aaacttttct aaaaaagaat ttataataaa gccatttata
    57721 acagttatga caatgtttat aatggttaag ttgagttatg gtgctttagt tggattctta
    57781 ggaaacagca tatctacaat aattgcaata tgtgttggtg gaattgtata tgtagtagta
    57841 atacttggaa taggtggaat taaaaaagaa gagattctaa ctatgccaaa aggtgataaa
    57901 ttatataaat tgttaaaaaa agttaaactt ataagataat ataggaatat atatgcaaat
    57961 aaaggaaata ctatacaaat agtaaatctc cttatttgta taataatata aaaataaagt
    58021 gaaatttgct aataggagtg atgttatggg taagataagt attgtaggtc ttggaccggg
    58081 agactattct cttataagcc aaggtgtgtt agaatcttta ataaatagcc ctaaagtttt
    58141 ttttagaaca gagaaacatc caataattga taaacttaaa gaaactatac aatacacttc
    58201 tttagactac ttttatgaaa aagaggaaaa ttttgataat gtttatttga aaatatctga
    58261 atttatcata gaagaatcag caaagggtga cctagtgtat gctgttcctg gtcatccaag
    58321 agttgcagag aagactgtaa gtataataga gagattagcc aatgaaaagc acatagcagt
    58381 agaaatattg ccttctatga gctttgtaga cgctatgttt aactatttgg ctatagaccc
    58441 atctgaggga tttaaactgg tagatgcttt tgaaatagaa aattcatata tagacttgga
    58501 tacaagtatg ataataactc aggtatatga taaatttata gcatctaatg taaagttaaa
    58561 acttatggaa cattatgact ataatcaaga agtatgtata gtaaatggag caggtgtcaa
    58621 agatttagaa agtaaaaagt ttataaagct ttgtgaatta gacagaaatg aaaacttttt
    58681 tgactattta actagcttat atatacccaa aagttctaaa aagatgtata atacagtaca
    58741 tgacttagaa ataatagtta atacacttag aagtccatct ggatgtgaat gggataaaaa
    58801 acaaacacat caatcattaa aaaattctgt tatagaggaa gcatatgaac tttgtaatgc
    58861 aattgataat aatgatatag atgaaatggt agaagagtta ggtgatgttc ttttacaggt
    58921 tatattccat tgtcagatag gaaatgagga gggctacttt gatttaaaag aagtagtaaa
    58981 tggcatatgt aaaaaattaa ttcatagaca tcctcatata tttagtggtg caaaattaga
    59041 tatgtctaag tttgagaaaa cttgggaaga attaaagaaa gaagagaaag gcgaaagtac
    59101 tataacagat ggccttagaa ggataccaaa acatttacca gctcttatga aggctagtaa
    59161 agttcaacat aaagcagcac ttgtcggctt tgattgggac aatgtagaag atgtatttaa
    59221 aaaaattgaa gaagaatatc aggaattact tgacgaacac agggtcggga atataaaata
    59281 cataaaggaa gagctaggcg atttattatt ttcgatagta aatctagcta gatttttaga
    59341 catagactca ggagaagcct tgaactgtac tacagaaaaa ttcataaata gatttgactt
    59401 tatagaaaaa agtgcaatga acttgaataa aaaattagaa gacatgacac ttgaagagat
    59461 ggatgagttt tggaatcagg ctaaaaaaca ataaaattgt ggaaggaaat ttgtcaaaaa
    59521 tctagaactt ttatcacaaa gatagaagtc tatattataa acatttttag gaggtaaata
    59581 tcgtgaataa agctgaatta gtatcaaaga tggcagaaaa aagtggatta acaaagaagg
    59641 aagcagaagc tgcgttaaac gcatttatga gttctgttca agatgcacta gtaaataatg
    59701 aaaaagttca attagttgga tttggaacat ttgagacaag agaaagagct gctagacaag
    59761 gaagaaatcc aagagatcca gagcaagtta tagatatacc agcttctaaa gcaccagttt
    59821 tcaaagctgg aaaaggatta aaggatataa taaatggata attagaaatc ttgtgaaaaa
    59881 gtgtggataa atttgccaca ctttttctat agaaccaagg aaggtgataa ttatgagatt
    59941 agataaattt ttaaaagtat ctaggattat aaaaagaaga actgttgcta aagatgcatg
    60001 tgataaaggg attgtcacta taaatggaaa agttgctaaa tcttcttcag aggtgaatat
    60061 tggagataca ttagaaatac aatttggaga gaagaagatg aagtttaaga taaatgaagt
    60121 aaaagagcat gtattaaaaa atgatgcaaa agaaatgtac gaaattttag aataaaatta
    60181 atagtcctct agtatattaa tagtagtatt attgaaatat ttactggggg gatattatgg
    60241 aacagaacat aactttgaaa gatagatcaa agctggttat ttcgggagtc gagcacatat
    60301 actcttttaa tgacaaaaga gtagagctca aaacttctgt aggcgagatg gtaattgaag
    60361 gcgaaaacct agatatgagc aagctaagta tagacgaaaa tataattagc atagatggaa
    60421 ctataaattc tatggtatat gcaaagccta aaaagccaca agagagtttc ttgaaaaagg
    60481 tatttagata gatgatacct tttactcaag atgtaagcat tttttatgct actatttatg
    60541 gtggaatact cataggggtg ttgtttgatt tttatagagg gctaagaggg aattttaaat
    60601 tcatcaatta ttttgctata atctttgatg tattgttttg gtttctagct acggttataa
    60661 tattcgtaac aataaacctt acagaatttt ttgatttaag atattatcat tttgtggctt
    60721 tgtttattgg ttttatttta tactataaca ccataagtaa aattgtttta tcaattatca
    60781 ataaaataat tcgttttgtg agaaattctt ttaaaaaagt tacacattac atagtcagtt
    60841 ttttaaataa tttgtattac gttataatct attcactaca cctactattt gatattatat
    60901 tttatatacc aaacatattt atagcaacaa gaaaaagtat aaaaagaaaa tcaaataaaa
    60961 aattaaagaa caagaaaaaa tcaaaaccta agaagaaaaa aaataaaact aaaaaaaggg
    61021 tgtaggaaaa atgaacttaa gaaaaaaatt ttcaggacag attattgtta tcagtttatt
    61081 tttaggaata tcaattttta gtatgatgac aggatttgta tttgagtata caaaagctaa
    61141 ggaatataaa aaagaaatag caagtctaaa taaacaatta aaaaagactg aaatacaaat
    61201 aaacagctta aagaaagatg aaaaatcata tgaaggagac ttagaggata tagcaagaaa
    61261 aagattgaat atggtaaaac caaatgaaac agtttatgta gacataaatc gttgattaaa
    61321 acttgctaat aagtttacag atgtattgat tttaaaattt aagatttaat aaaaaagtca
    61381 ttcagttaag gatggctttt tgtttttatt gaggagggaa tttcataatg aaagtaggag
    61441 ctatagatat tgggacaaac tcaatgagat tactgatagc agattataga gatgggaatt
    61501 ttataaacag aaaaaaattt gttaatacaa ctagaattgg ttatggtgtg gatagtaaag
    61561 gatatataaa agaagatgct atcaaaagaa atataaaagc attaaaagaa ttttctgata
    61621 agtgtaatga tgaaaagtgt gaaaaaattt attgtatggg gacatctgct cttagagaca
    61681 gtaaaaatgg agattacttt gttaaattag ctaaagaaga aactggaata gatgttgata
    61741 tagttacggg aatagaagaa tcaaatttgg gctttaaggg tgttttagaa ggaatacaag
    61801 gtgatgatac tattattgtt atagatattg gaggaggttc aacagaattt attgtaggtg
    61861 attcagaagg aattaaattt aataaaagtg agaatgtagg tgctcttagg atgacagaga
    61921 ggtttttgaa gcacgatatt attgaagatg aagagtttga agctatgagt tcatttatat
    61981 atgatgagat tgacaaaacg ttaaatcata taaaagacag aggattaaaa actcttatag
    62041 gtataggagg tacgattaca tcattatcag caatgaatca agaattagag atttactcta
    62101 tggaaaaaat acataatagt aaaatacaca aaaaagaaat agaagaaatt ctacaaaaat
    62161 taataaagat gacattaagt gataaaaaga acttaaaagg gctacaagaa aaacgtgcgg
    62221 atattataac tgctggtgta aaaatattga atataataat ggaaaaatta gaaatagaag
    62281 aaataaccgt aagtgaatac gataatttgg aaggcttaat atgtcaaaag tcaaaaaaaa
    62341 tgtattaata ttttttgatt tttaaaaccg attatgacaa aaaaaattac tcctctttgt
    62401 tacaattctt aatataaaca aaagaggagg tttttttatg caaagaagtg tagcagttgt
    62461 gaagaataag actgtaaaac caaatgtcat aaaattaata agcggatata ttgattttac
    62521 tacggcggca ttcgctgtga tgggattttt acttagtagg tctattatag tagactctgt
    62581 agctccttta ggaattgcct tttttatatg tgcatcaaag attgataagt acaagatacc
    62641 tgtattcata tcaacattat taggaatatt gttatcatct aatgattttg gaaatgtagc
    62701 aaaatatgct gtgtgcctta caatatttat ggctatgaat aaaaaattaa aattatcaga
    62761 ttcaattgct aaggttgcat ttataggtgc aataatacta cttccaatct ccatgggaca
    62821 agctttcttt tcaaataggt atgtatatgg tcttcttata gcaggagtag aagcaataat
    62881 aatgtttata tctatatatg tgttttctta tgggataggt ttaatggcca atgtcaacaa
    62941 taggatgtct gtacggacag aagaagctat atcaataagt ttactgctaa cctttagcat
    63001 aatgggaata ggagatatat ctctgtttgg aatatcaata aggaccattt tatcgaccgt
    63061 attgatattg ctgacctcaa tagtaggtgg agctaccatg ggagcatcta gtggtgtaat
    63121 tattggtgta gcatccattt taaataatat gacatcagct gtttatatgg ggatatattc
    63181 tttttcagga ttaataagtg gagcatttaa taaaataaat aaatatttct gtatactagg
    63241 atatattcta agttggacaa taatatacct atatacttct ggtattactt ctaatatgat
    63301 gcaattaaga gatatactat taggttgttt gatagtacta gtattgccag agagattatt
    63361 taataagatt gaaaaattaa taaaaagtaa tgtggcttca aatgaaatcg tatacgatta
    63421 tattatgaga agcaaaaacc taactaatag cagattgaac agtatttata aaacttatga
    63481 tgaccttgca gatacatttg ataagataag agaaaaagac aaagtgctag accaaagaga
    63541 tatagctaat gtaatagata tgattcataa tgatgaatgt aaaagttgta gtatgagaag
    63601 aatgtgctgg gagtcaagat ttaatcatac atacactatg atatataaca ttcttgaaaa
    63661 aattgaggag aaaggggagt taagtctaaa cgatatacct aaaaatttta gaaaggaatg
    63721 tatgaaacca gagtcgatag tgaaaatatc aaatcactat tacaaaatgt ttgtattaga
    63781 ttatgattgg agtgtgaagt tttcagaaag tagaaagtta atagcaaatc agataagaag
    63841 tatttcaaaa tccattaaat ccttatctca agatttagaa ggtgacataa tgctagatat
    63901 agaaaaggaa aaaaatatat atgaacagtt agaaagatat gatataacag ttgataaagt
    63961 aagttactta acaaaaagta acaatgagtt tgaaatatca atagaaaaga aaacttgtca
    64021 tgatggatgt atgtgtgaag ataaaattgt aaatataatt tcagacctag taggtgaaaa
    64081 tatgtctgtt agaaaaatag gatgtcactg tttaggaggt aaatgcaagg caacattcgt
    64141 taaatctcaa aaatataagg ctgttacaga agtttcagca atgtcaaggg atgggcatat
    64201 cctttgtgga gacaattaca catacatgga gataaatgat ggtaaataca tgatggctat
    64261 aagtgatggt atgggaaagg gtaaaaaagc atatgaagaa tcttctgcca ctattgatat
    64321 actggaaaaa atgatagatg caaaaattaa agatgagata gtcattgata ctataaataa
    64381 tatgttgttg ttaaaatctt cagaagagat gttttcaact ctggatttgg gaattttaga
    64441 tttaaaacga ggttgtttag aaactataaa gatgggagcg tgttctactt atataaaaag
    64501 agaggatgga gaagttgact taatatcatc atcatcatta cctgtgggta tattatcaga
    64561 tgtaaaaatt gatagaaaaa atgtaaaagt taaggaagga gactatgtta taatggtttc
    64621 tgatggaatt gtagatgcag gaagaaataa caatttagga gacaattggt taatatactt
    64681 cttaaagaat atagagacta caaatccaaa ggaaatttca aacttaatat tggatagagc
    64741 attagagtta caagcgttac aaatcgaaga tgacatgact gttttagtta cgaaaatatg
    64801 tacaaaataa ggtttacaag attatgtgta taagatgtgg ataacttgtg tataatatgt
    64861 taatagactt ttgaaaaaag tatagttatt aacaaaaata acatataaat caacaaaatt
    64921 tgttgataag tatggcagaa atgttaataa aatgtaaaaa aagaaaaaac aaaagctatt
    64981 atcaaaagag attcatgttg aaataactaa atttctaagt aaagaaaacc tgtgaatatg
    65041 ttgattatta tgtggataac tattaattcg atatttattt atatagtatg aataattgaa
    65101 taatatatct aaaaaaagcc atcctattat taagtaaatt tattgaaagg atggcttttt
    65161 atgaatagaa aattgtgcaa agcaataata cctttattta tttctatttt ttgcatgtta
    65221 ataataagta taaaagctga ccaaggatat caaaagaata atgacagagc aattgctgtc
    65281 atgaataata atgatattga agatgatgct gaaaaaaaac aagaagtaga ctatgaaaaa
    65341 acatgttgga atttgcaatc tttgttcaaa agtgatgacc aatggaaaaa agaacttaag
    65401 agttttgata aagatactaa agagttgaaa aattacatag gtaaagtaac aaaatcgcca
    65461 acacatttgt cttttgcctt aaacattaag gaaaaacttg atataagact aaataaactt
    65521 tctgcctatg taaaattaaa acaagatact aataaaaatt catataagta cttagatatg
    65581 agtgatagta tgagtaaatc atatggaaat tatatgggga tttgttcaga tttagaatta
    65641 gaaatactaa aattatcaaa caaagattac aagaaaatta tttcaaataa aaatataaat
    65701 aggaaatatg gtgcatattt aagagatata agaaggaata aagtacatta tttggatgat
    65761 aaatcagaag atattctaag caaagtatct tcaataagta gtcttccaag ccaagtatat
    65821 gaattattta gaaatatgga tagaaaaact aatttgacac cagcgcaata tgcaagtgaa
    65881 ttagagtcag tagatagaga aaatagaaaa aaagcttatc aagatgaact tataacttac
    65941 aatgataata taaatacaat tgcaggttta attactggtc aagttaaaaa gaatattttt
    66001 tattctcagg aaagaggtta tgagtcttct ttagaaatgt acttggaatc tgataatgta
    66061 gatgaaaaag tatacaataa tttgataagg actgtaaata gtaatatgga cagtctacac
    66121 aaatatatag atttaagaaa aaaagtatta aaattagata aggttcattc atatgatatg
    66181 tttgtgccta tggttaaggc tgttgataat aatattaatt atgaaaaggc acaaagtata
    66241 gtatattcag cgttgtcacc gttaggaaaa gaatacaatg atgtagtata taaagctttc
    66301 aatgaaaaat ggatagatgt ttattcacat gaaaataaag taagtggtgg atactgctta
    66361 tctgtttatg aaaatcatcc atatatactt ttaaattata ataattcatt aggttcagtt
    66421 tcgactttat cacatgagct tggacatgct gtatatgaat acttaagttc taagaatcag
    66481 aattatttta attcaaatcc gtctatattt actcacgaag ttgcatctac aacgaatgaa
    66541 gcattacttt acgagatgct tataaaagaa gctaaaggca atgatgaaaa agcttattat
    66601 ataacacagt atttagactt gataaaagat actctttata cacaaactat gtatgctgaa
    66661 tttgaaaaaa ctatacacga gttagtagaa aaaggaaaaa gtgtaaacgc attagtatta
    66721 aatgatgttt ggggacaact tcttaaaaaa tattatggac aaagctatga attagaccaa
    66781 ttatctaagg tcggatgggc tagaatccca catttttata atagtttcta tgtctataaa
    66841 tatgctacag gttgtagtgc aggagtaagt tttgcccaag acatcctaaa gaatggttca
    66901 gataactata tgagctttct taaaaaggga agttcagatt atccaataaa cttgttaaaa
    66961 tcaagtggca taaatttaac taatacaaaa cccatagaaa atacaatcaa aaaatttgat
    67021 agtttagtag cagaacttga aaagctatta taaacattat tgtaatccac atggtaaata
    67081 tatcgaatta atgataaaat atactaaaag tttaaagtcc tatcaagata ggacttttta
    67141 tttattaatt agtgggagat gattctatgc aagttaaagt taaaaaggct gtaataccag
    67201 cagcaggttt aggaactaga tttttgccag ctacaaaggc acaaccaaaa gagatgttac
    67261 caatagttga taagccaact ctacaataca taatagaaga agctgtggcc tcaggaatag
    67321 aggaaatact aataataaca ggtagaaata aaaaatctat tgaagaccac tttgataaat
    67381 ctgtagaatt ggaacttgat ttagagaaaa aaggtaagaa agaattgttg gaggtagtac
    67441 aaaacatatc taacatgatt aacatacatt atataagaca aaaagagcca aaaggattgg
    67501 gagatgcaat ttattgtgcg aggcatttta taggtgatga gccgtttgca gtaatgttag
    67561 gggatgatat tgtagataat gatgtacctt gtctaaaaca actaacagat gcatatgagg
    67621 aatatagaac tacaatattg ggtgttcaaa aggtaaatca agaagatact aataaatatg
    67681 ggataataga agcaaaaaat atagaaggta gagtttacaa ggtaaaagac atggtagaaa
    67741 agccagagtc aggaaaagct ccttcaaata ttgctatttt aggtagatat ataataactc
    67801 ctgaaatctt tgatattctt aaggatttac caccaggtaa aggtggagag gtacaactta
    67861 cagatgcttt aaaaatatta tctaagaaag aagctatgta tgcatacaat tttgaaggca
    67921 agagatatga tgttggggac aagctaggat ttttagaagc tactgttgac tttgctctaa
    67981 agaaagaaga ccttaaggaa gattttataa aatatttgaa acatgtatgt agtgaatttg
    68041 ataaaaataa caatgtgtta tacaataata cagatgaaaa aatagattta attgaagtca
    68101 atgaagctag agaacttgaa attcaaaaat aattaatgaa aggtgatgta tggtggcaaa
    68161 atcaagtcag aaaagaatta atagaataat agctgttggg attgtgggaa tcctcgtaat
    68221 aacgagtata acagctgttt tgagtatgat tgcaactatg taataagata aatgacagca
    68281 gttgatatac ataaatataa aaaccatata taacttgatg tagtcaaaaa cttacaatat
    68341 tttagttata tatggttttt agaatttata aatgtaaaaa aaaattttta taatagttgc
    68401 atattttaaa ggaaaatatt attataagat ataaatatag tgataaattt ataaaaacgt
    68461 gctaagattg gacttgaaat acagtaatat agtaggtaat aatgttttaa attttattta
    68521 ttgaccataa tatataaata atgatattat tagacttaac tgtttaaata aaacttttct
    68581 ttttcatgcc ttcaatttcc aaaataagta tgtatataaa tgaatatata gatgaggagg
    68641 atttttttga ttttagatga taaagtatta gaaggattag gtagtaagac cttagttgag
    68701 ctacgagaga tagctaaaga attaaaaata aaatcaatta ctacatataa gaaaaatgag
    68761 ttaattgaga ttataaattc caaaagtaaa aatgaggaaa aagtaaacga agagactaaa
    68821 gaaaaaaatg aagatattaa agaagacata aagaatagaa aagaaaatat agagcgtgaa
    68881 agtatagaaa aagaagttga atataagagc cctaccaaat catacaacaa gaaagaaata
    68941 gatacccaaa atatttccca aaaccaagaa aatagaaatc aaagaaatga ctataataag
    69001 acaacgagtg taaatgatag taataagtca tcaaatatat ctaatagaat ggtcagaaat
    69061 aataataaaa actattatat gcctaaacaa gttgatgaat ctaagatagt agatgaattt
    69121 aacacatcaa aagaggatga agtagtaggt gtacttgaaa ttctgccaga tggatttggt
    69181 tttttaagag gttcaaatta tttgtctact gaaggagatg tttatgtttc accatctcaa
    69241 ataagaagat ttaatatgaa aacaggagac aagattaagg gaataactag acatccaaaa
    69301 agtggagaga aatttagagc acttttatat gttcaaaaaa taaatgatga aaaccctgat
    69361 acagctatac aaagaaatgc gtttgagaca ttaacaccaa tatttccaga agaacgactt
    69421 acactggaaa ctaatagaaa tgaaatagct acaagaatta tagatttaat ttcacctata
    69481 ggaaagggac aaagaggatt gatagtagca cctccaaaag ctgggaaaac agtcctttta
    69541 aaaagcgttg caaatagcat agctaaaaat catccaaatg ttgaacttat agtactcctt
    69601 atagatgaaa gaccagagga agttactgat atgaaagaat ctattgaagg agacgttata
    69661 tattcaactt ttgaccaagt atcaagtcat catgtcaagg ttgcagagat ggtgttaaat
    69721 agagctcaaa gattagttga acatggtaaa gatgtagtaa ttttactaga tagtataact
    69781 agattggcaa gggcatataa ccttacaata tctcctacag gtagaacttt atctggaggt
    69841 attgaccctg gtgcacttca tggacctaaa aagttctttg gtgcagcaag gaatattaga
    69901 cagggtggtt ctttgacaat attaggaaca gcattggttg aaactggttc taggatggat
    69961 gatgtaatat ttgaggaatt taaaggtaca ggaaatatgg agctacattt agatagaaaa
    70021 ttagcagaaa aaagaatatt ccctgcaata gatatttaca agtctggtac aagaagagat
    70081 gatttattgc ttgatgatga agaaaagact gctctttgga aattaagaag agaaatgagt
    70141 aataattcag taatggaaat tacagataaa gtcattgaac ttataaagag aactaaggac
    70201 aataaagagt ttgtaaaatc aataaagaat ttgtaaaatc aataatacaa atgcaaatat
    70261 ggattatata aactaataga aaaatcactt gaatggcata ataagttgtg ctataataat
    70321 gtagttgata atgtaaaaag aaagttaata taattaattt ttttaaataa agagaagagg
    70381 tgactataat gcaaaaggaa atacaaccaa aatacaatcc agttgaagtg cgttgtgctt
    70441 gtgggaacac atttgttgct ggttcaacta aggacgaaat aaaagttgaa atatgttcag
    70501 agtgccatcc attctataca ggaaaacaaa agaacataga aaaaggtgga agaatcgaca
    70561 aattcaagaa aagattcaaa atggactaat ttttataaaa gtggagttgg aggaagccaa
    70621 ctcctatttt attacaaaaa aacattcata ttctacttta aattgtcttt ttgtattata
    70681 ataataaata tgtaaaattg agtattctaa atacaataaa atgaggtgag tggatggcaa
    70741 aacaagctgt aggtgggcaa gctgttattg aaggtgtaat gatgcagtca aaagacaaaa
    70801 gagcggtagc tgttagaaaa agtgacgggg aaatagcact aaaagaagat agaataaaaa
    70861 gttgggtaag agataagaat atagataaga taccttttgt tagaggttct tttgttatga
    70921 tagatacaat gattcaaggc ataaaaagct taaacttttc ttcagagttt tttatggaag
    70981 aagctgaaga ggataaattt gatttattta taaagaaaat ttttaaagat aaggcaaatg
    71041 atataattat aatattttca ttggtcatag caatgttact ttctgctgga ttattcattt
    71101 ttatacctac attggtagga ggagcttttt ctaaagtaat gcctaatgat tttatgctta
    71161 atttaataga aggaatcata aggatagtta tattatttgc atatatagta ttgatttcac
    71221 gaagtaagga tatagaaaga gtctttcaat atcatggagc agaacataaa tctatatatt
    71281 gctatgaaaa tgatttagaa cttacagtag agaatgctag aaaatttaaa agattacatc
    71341 ctagatgtgg tacaaatttc ctatttatag ttatggctgt atcaataata ttgtttgcat
    71401 tttttggttg gccaaatcca attcttagaa tatttatgag aattatatgt gtgcctatag
    71461 tagcaggttt atcttatgaa gtaattagag ttcttgggaa atatgataat ggatttacta
    71521 aaattattgc atatccagga atgatgttgc aatattttac aacaaaagag cctgatgatg
    71581 agcaattaga ggttgctttg gaagcattga aagcagtagt agattagaga aaaggatatt
    71641 tgttatgacg ataaaagata taattattaa atattcagat aaactaaaag atataagtga
    71701 tactccaaga ttagatacag agttattgtt acaaaaaaca ttgggtgttg atagattata
    71761 tattcactta aatctgagta aagagctaac tgaagaacaa aaaacaaaat ttataggttt
    71821 tgcagaagaa agattaaatg gaagaccaat agcatatata gttgaaaata gggagtttat
    71881 gggattagat ttttttgtta aggaaggcgt attgattcca agaccagata cagaaacttt
    71941 agtagaagaa ataattgaaa tatgtagaga aaaaaaagat gtaagtatat tagatatagg
    72001 aactggttct ggagctatta caataagttt agcaaagtac attgaaaatt ctaaaatcat
    72061 gtcttttgat atatcagaga cagcattaga aatagctaaa aaaaatgcta ttataaatga
    72121 agttggtgaa aaaataaagt atattaattc tgatttattt acagcaataa gtgatagtaa
    72181 cataaaattc gatatcatag tttcaaatcc accatatatt aaaaaacaag atatagaaac
    72241 tctgcacaaa caagttaaag attatgaacc atataatgct cttgaaggtg gagaagatgg
    72301 attagacttt tatagaagaa taacagaaca aggtaagaaa tatttaaata agtgtggaat
    72361 attagcatat gaagttggtc ataatcaagc tgaagatgta ataaatatta tgaaaagtaa
    72421 tggatataaa aaaatataca caaagaagga tattcaaggc attgatagag ttgttatagg
    72481 ttacaatata tgatataatc aacaattgat atgttacatt taatcgaggt gaaagtatgt
    72541 taaaaaaatt agaggtattg gaagatacat ataaagactt aagtgaaaaa ataggtgatc
    72601 cggatgtaat aaatgatcaa aaagtttggc agaaatatat aaaagaacat gctgacttgg
    72661 aacctattgt tatgaaatac agagagtata aaagcgtttt agataggata aaagaatcaa
    72721 aagaaatttt acaagaagag tcagatgaag aattaagaga attagctaaa atggagttag
    72781 ctgagatgga agaaaaagta gcacctctgg aggaagaaat aaaaatacta ttattgccta
    72841 aagaccctaa tgatgataag aacgttatag ttgaaattag aggtggagct ggaggagatg
    72901 aagcagctct atttgcgggt gatttattta gaatgtactc aaggtatgct gaaagaagaa
    72961 gatggaaaat agaattattg agtgcaagtg atactggagt tggtggatat aaagaagtat
    73021 cttttatgat aaaaggtaaa ggtgcttatt caagattaaa gtatgaatct ggagttcata
    73081 gagttcaaag aataccatca actgaatctg gtggaagaat acacacatca acttctactg
    73141 ttgcagtatt accagaagtt gaagatgtag aggttgaaat aaatccaaat gatttaagaa
    73201 tagatgtttt ccgttcttcg ggtaatggag gacaaagtgt taatactact gactctgctg
    73261 ttagggtaac acatatacct acaggtgaag tagtatcttg tcaagatgga aaatcacaat
    73321 taaaaaataa agagcaagct ttaaaaatat taaaagctag actttacgat aaagcattgg
    73381 cagaacaaca caaagatata gcagcagaaa gaaaaagcca agtcggaaca ggagacaggt
    73441 cagaaagaat aagaacatat aatttccctc aaggtagaat aagtgaccat agaataaatt
    73501 taactttata taagttagat gcatttttag atggagatat agatgaaatg atagatgctt
    73561 taattactgt tgaccaaaca gaaaaaatga ctgcaatata agtaatgttt taaagaagct
    73621 gtttcttcct agaaattatt ttctattttg aaacagctat tttgcatttt aggtcatgtt
    73681 atcatattct attgtatata attgttatat acaagtatag gagggttata tgatactaaa
    73741 agtaacaata attgggcttt tggcaggtgt tatagggaca ggattaggag gagtaatatc
    73801 agccattttt aaaagagagg tcgataaata tctaagtttt tttatgggat tatctggtgg
    73861 aataatgttg gctgtagtgg tgtttgattt aatgaaagaa tccatggaca aaatggggat
    73921 aatcaataca gttatattta cgtttgttgg agctctcata actatgtaca taaaaacaaa
    73981 attagatgtg tctggaaata tggcatctgg atatcttata ttcataagta tattactaca
    74041 taatttacca gaaggactag ccattggttc ttcttttatg tcaactgaaa gtttaggtat
    74101 tacacttgct atagttatag gtctacataa tataccagaa gggttagcta tggcattagg
    74161 cttagtttgc aataaaatga aactaagtaa agttattttg tttactgtaa tagctggatt
    74221 acctatgggt ctaggaagtt ttttaggtgt ttattttgga ggagtattta cttctcttat
    74281 aggagtattt cttgctacag caggaggtac tatgatgtat gttgtattgg aagaaatttt
    74341 tccacattca aaaagtgtgt attgtataat tggtttcttg ttaggtacaa tgattgtaaa
    74401 ttatatataa aattaaaatg aaagcaggca tacaaaagat gaaaactatt ataagtaata
    74461 ttgatataaa taatattgat tatgaggaaa taaaaataca agcaaaactt cttagagaag
    74521 gtaaaacagt tatttttcca actgagacag tatatgggtt gggtgcaaat gcattagatg
    74581 aaaatgcagt aaagaagatt tatgaagcta aaggaagacc tagtgacaat ccattgatag
    74641 tccatatata tgaaaaagaa gaagtatatg acttagccaa agatataagt gataaagcta
    74701 aacttgttat agaaaagctt tggccaggac ctataacaat tatattaaat aaaaaagata
    74761 taattccata caaaactagt ggagggcttg atacagttgc aataaggatg ccttctaatg
    74821 ttattgccag ggcaataata aaagaggctg gtatacctat tgcagctcct tctgcaaata
    74881 tctcaggtcg cccatctcca acaaaagcaa aacatgtata tgaagagatg aatggaagag
    74941 tggatggaat agttttagga ggagacagta attttggatt ggagtcaact gtattggatt
    75001 taacagaaga gactcctatg atactgagac caggaagtat aactaaagaa gttttagagg
    75061 aacttcttgg agaagtaaag cttgacccat cattaagtaa aaaagaagat aatcaaaaag
    75121 ctaaagctcc tggaatgaaa tataaacatt attctccaaa tgcagatgta tatataatat
    75181 ctggaaaaag agaaaatgta gcaacaaaga ttaatgatat gataaaatct aatagagaca
    75241 aaggtctaaa gacaggtgta atgtgtatca gtagaaaccg agagttttat gatggagaag
    75301 taatcgattt aggaaactct cttgaagaag ttgcaagtaa tctgtttgat gctcttatag
    75361 aaatggacaa aaagggtgtt gatgtcatat attcagaaga gttccctaag actggagttg
    75421 gacaagcaat tatgaataga ctactgaagt cagcaggata caaagtgata aaggcttaag
    75481 agggagttgt aaaatatgaa tatacttatt gtgtgtacag gtaatacttg tagaagccct
    75541 atggctgagg ctatactaag gaaagcaatt aaagaatctg gaagaagtat tgaagaatat
    75601 tctatatcat cagcaggtat atctacagca aatggaatgg gtgcttctga aaattctata
    75661 gaagtactaa aagaaatcgg tatagactta tcaaatcata gaagtaaagt aattactaaa
    75721 aaattaattg atgaatcaga tataatacta acaatgacta aatctcataa agaaatttta
    75781 gtacaagcag ttccaaaatg caaagaaaaa gtgtatactt ttaaagggtt tgcaaataaa
    75841 aatgaggaag atatatctga cccatttggt ggaaatttgg atatttatag aagcactatg
    75901 agagaaataa tgtattctgt caacgaaata gtaaaaaaaa tatgaaatgg aggataaaca
    75961 aatgaagata ggattaggct gtgaccatgg aggatataat ttaaaaaaag aaataataag
    76021 ctatttagaa agtaaaggta tagaatgtgt agattatgga actaataatg ctacagattc
    76081 tgttgattat cctgtttatg gagaaatagt tgcaaattca gttataaata aagaagtaga
    76141 ttatggaata ttatgttgtg gtacagggat aggaatatct ttagctgcta ataaggttcc
    76201 tgggataaga tgtgcagttg tatcagatgt attttctgca aaaatgtcaa aagcacataa
    76261 tgatgcaaat atgttatcat taggcgaaag agttttagga aaaggtctag cacttgagat
    76321 agttgaagca tggattaata cggattttga aggtgataga catgctagaa gagtaaacat
    76381 gattaaatca atagaagaaa aacataataa ataataaaaa ttacagtttt atcaggagga
    76441 attatcaaaa tgagcaaagt ggtagagaca aaccatccat taatacaaca taaattaact
    76501 ttaatgagag ataaaaatac tggttctaaa gactttagag agcttttaac tgaaattgca
    76561 atgttaatgg ggtatgaaat aacaaaagat ataccattaa aagatgtaga aatagaaact
    76621 cctattcaaa aaacatcatc taaagtagtt gcaggtaaaa aattagcaat aattccaatt
    76681 ttaagagcag gtcttggaat ggtagatgga ttagtaagct taatgccagc agcaaaagtt
    76741 ggacatgtag gactatatag agacccagaa acattaaaac cagttgaata ttattgcaag
    76801 cttcctcaag acataggaga aagagatata atagtagttg accctatgct tgcaacaggg
    76861 ggttctgctg tagcagctat agatttactt aagtctaaag gagctaaaag tataaaatta
    76921 gctaatttag tagctgcacc agaaggtata gcagaagtgc aaaaatatca tgatgatgtt
    76981 gatatatatg ttgcatcagt tgacgaaaga ttaaatgaac atggatatat aattcctggt
    77041 cttggtgatg ctggagatag attgtttgga actaaataaa aataaataac tataaatatt
    77101 tattagggac tttcttatat agtgtatata attttatgta agaaggttct tttttatata
    77161 ttttttctca aaataggaat tatgaattga taaatttctc gaattgagaa taaaaagttt
    77221 ttaccaatta aaaaagattg cttattttac aaggttttat agaatagtag tctattttaa
    77281 tgtggcatgt tagttgctta cgattaagat tataggtatt aagtgtatta gttaaattga
    77341 gaattgaata ttaataatat tattgggagt ggtaatacat gaagaattgt atagcagtaa
    77401 gaggggctgg agatttagca acagcagtta ttcataaatt acacaacagt ggttttaaag
    77461 tagttgcgtt agaaatagaa gagccattag ctataagaag gcaaatttct ttttgtgagg
    77521 ctgtttatga aaaaaaagta actgttgaag gtgtagaatg tatattttgc aatactgaaa
    77581 aagaaataga agaagtttta tctcaacata aagtagcctt gattatagac ccaaaaggag
    77641 aaaaattatc taagttaaat ccaatcgttt tggttgatgg aatactcgct aagaaaaact
    77701 taggtacaac taaagatatg gcaccactta caatagcttt aggtcctgga ttttgtgcag
    77761 gagaagatgt agatgttgtt atagagacaa tgagaggtca taatctagga agaataataa
    77821 ctaatggtag agcagaaaaa aatacaggag taccaggagc aataaaaggt ttttctaaag
    77881 agagagttat gcattcacag tatgatggta taatggaaaa tgtatgtaag ataggtgata
    77941 tagttgaaaa gggagaccta ctttgttata ttaataatta tgaaaaaaaa catgaagtta
    78001 gagcaacaat atctggagtc cttagaggtt tattaaagga tggagcaaag gtgaacaaaa
    78061 atttaaaaat actagacata gaccctagaa aagaagaagt taagaatgct tttacaatat
    78121 cagataaagc tagatgtata gctggagggg ttttagaagc catactaaac aatgggattt
    78181 atccccaaaa ttaatttata ttagataaag ctattaatat tttattaaga tgatataata
    78241 aatttaatag attaaagaga gcatatgacg ggtatttaaa atttaaatgg taaaaatgct
    78301 ctttttttat tggacattca attaacatgt gtatataata taaaaataag tatttattta
    78361 ggttgaaatc taataaatat ataataccag tacataagca aagaggagaa aagtaaatta
    78421 tgagaccatc atgggatgaa tacttcatgg aaattgcaga agtagtgaaa aagcgttcaa
    78481 cttgtattag aagacaagta ggagctgtaa ttgtaagaga caaacaaata ttaacaactg
    78541 gatataatgg ttctccgaga aatcttgaac actgtgaaaa tattggatgt aagaggcagg
    78601 aattaaatat tccctcagga gaaaggcatg aattatgcag agcattacat gctgaacaaa
    78661 atgcgataat acaagctgct cataatggta ttagtgtaga tggggcaact ttgtatgtta
    78721 ctacaagacc ttgtgttttg tgtgcaaaaa tgtgcataaa tgcaggtata ttgaaaattg
    78781 tttatgaagg tgattatcca gatgatatgt ctacagaatt attaaaagaa gcaggaatag
    78841 aactcataaa attttagtgg ataaaattta tatgacaata aatgtcaaat tatgacactg
    78901 aaatacaatg gtatcaaatg attaaaagaa agtatttgaa aaatcatcag attagtagta
    78961 agatatattt tataattaaa taaatttatg agatagatta attacatgtt atttatttta
    79021 taataatgag ggatactatt tatgagtaaa agaaatacac atacagaaat tgcaaagttg
    79081 tttagtttaa taagtcaaat aggattgatg attgtaatat caatattagg atgtactttc
    79141 ttaggaaaat ttttagatag taaattgaat actactccag ttctgacaat aatatttttg
    79201 ttgttgggtg ttggaggtgc ttttagtggt gtttataaaa ctctaatagt atatacacga
    79261 aggaagtgat atattggata taaaattact taaccaggta aggtcagtaa caaaaggtat
    79321 agtaatattt gatgtagttt taattgtgct aatgttgata acatcaacat taagtaaacc
    79381 agtattatta ggacttatat ttggctctat aatagctatg ttaaatttta gattattggc
    79441 gatatcactg gaaaaatcag tgacatttcc tgctgggaag gcacaagctt atgcatcagc
    79501 acaatatgct gttagattat ttataatggc agttgttcta attgcatcag ctacagtacc
    79561 acatttaaat ataatcggaa cagcattggg attattgagc acaaagtttg tcatattatc
    79621 aaaaaacttt ataaataaat taaagaggaa ggaggcataa gtatgaatca agcgcattat
    79681 tatctcatag gaaactttaa gattagtgaa acaatactag taagttgggg aataatggcc
    79741 tttttagcga tagcatctta ttttttgact agaaacttaa aaaaagttcc aactagtaaa
    79801 gttcaaatat tcttagaatt tgcagtaggt ggtcttgcta aaatggttac agatgttatg
    79861 ggtaaaaata cagtaaaaag aatgccatat atgataccat acataggaag cttgttttta
    79921 tttttcgcat gttcaaattt aagcccatta cttggattaa ggtcaccaac aaccgactta
    79981 gacacaactg ctgcatgggc aatgattaca ttttttatga tttattttgc aggagttaaa
    80041 tttaaggggt tatcatactt taaagaattg gctcaaccac ttgccataat gttaccaatc
    80101 aatattatag gtgagttagc tagaccaata tcattaagtt tccgtccatt tgggaatatt
    80161 ttaggtggaa caataataat gggtctgttt tatcaacttt taggttttat atctagttta
    80221 ataccaggat tatcaatacc aattggagaa atattaatac cagtcccatt acacttgtac
    80281 tttgacttat ttgcaggatt gttacaagca tatatattta taatgttaac aatggtattt
    80341 atatcaagtg caggagagtt agattaagaa atcaacttat attaagataa aaataaaata
    80401 atttaaaaaa ttaaagtttt aaggaggaaa taattatgga aacagcaata gtagcggcag
    80461 catcagcaat aggagcaggg atagcagttg caacaggtat aggtgcaggt ataggtcaag
    80521 gtatagcagc agctaaagct gcagaagcag taggaaacca gccagaagct aaaggtgata
    80581 taacatcaac tttattacta ggagttgcta tagcagagtc ttcagcaata tatggtttgg
    80641 ttatatcaat aatacttcta ttcgtaaatc cattctttaa atacttagga atgtagattt
    80701 agtccttaaa tattttgaga taggtttata ggtaaatcat ctcaaactta taatcatgag
    80761 atgaacttta tcatctcgtg attataagta gttatgattt atggaaagga ggataattat
    80821 ggaaaaagca ctagtaggta taacgtggga atttgtgttc caaattgtta atacttttat
    80881 aatattttta cttctgagaa agcttttatt caagccagta ttaaatataa ttgaatcaag
    80941 agaaaatgat attaaaagtg atttggcaga aggcgaaaaa gcaaaaaatg aaggtttagc
    81001 tctgaaaaaa gaatatgagt caaaaatcaa ttttgccaaa gatgaaggtc aagaaatcat
    81061 aaaacaagca actataagag cagagcagaa atcagatgat atagtaaata ctgcaaagaa
    81121 agatgctctt gatataaaag aaaaagcaaa caaagatata gaacaagaaa gacaaaaggt
    81181 cataaatgaa atcaaaaatg atatatctaa catagcacta cttgcagcat ctaaagttat
    81241 tgaaaaagat ttagataaat ctaaacatga agaattgata gaaaacttta taaaagaggt
    81301 aggggaagct aaatgataaa tgtaatagca aatagatatg ccgaagccct atttcaatta
    81361 ggagaagaag aaaattcaac tgatgtctta ttcaaagaac tagaaaaagt agtagatatg
    81421 atgactaaag ttagtaaaga tttctacaaa gttttaaaat caccattagt ttcaaaatca
    81481 gaaaagaaaa acttggtaga aattattttt agtaaggaag taagttctaa cataaaaaac
    81541 tttttaaaag ttttagtaga taaagataga atatcatatt tagaagatat cgaattagct
    81601 tataaagaat tattaaataa gaaaaacaat gtaattgatg gagtagcaat aagtgctatt
    81661 ccaatgagtg aaacagatat taaagaactt gaagtcaaac tttcaaataa atacaacaaa
    81721 aatgttacta tagaaaatgt tgttgacaag actatactag ggggagttct agttagaatt
    81781 ggaaatgaac aaatagatgg cactgtgaaa actcgtcttg ataagatgaa agaaaagcta
    81841 tctgaagtaa tatcttaaga atggcggtga acccatgaac ttaaaacctg aagaaataag
    81901 ttctataatt aaacagcaaa taaaaaatta tgagaataaa gttgagttga cagatacagg
    81961 tagtgtttta acagttgggg atggtatagc gagtgtatat ggattagaaa aagctatgtc
    82021 tggtgagttg ctagagttcc caggtgaaat atatggtatg gcacttaact tggaagaaga
    82081 agtagttgga gctgttatcc ttggagatga cagtgaaata aaagaaggcg atatagttaa
    82141 gagaactgga agaatagttg aagttccagt tggagaagct ttaataggta gagttgtaaa
    82201 ctcactaggt cagccaatag atggaaaagg acctatagcg tacacaaaaa ctagaccagt
    82261 tgaatctgag gcacctggta taatagatag aaggtctgtt tatgaaccat tacaaacagg
    82321 aatcaaatca atagattcaa tgataccaat tggtagaggt caaagagagt taataatagg
    82381 tgacagacaa actggtaaaa catctatagt tattgacact atactaaatc aaaaaggaaa
    82441 agatgttatc tgtatatatg tagcaattgg acaaaaacgt tctactatag ctcaattagt
    82501 tagctcttta gaaaaaggtg gagctttgga ttatacaata gtagtttcag caacagcatc
    82561 tgaatcagca ccacttcaat atatagcacc atatgctgga gcagctatgg gtgaagaatt
    82621 tatgtacaat gggaaacatg tacttatagt gtatgatgat ttaagtaaac aagctgttgc
    82681 atatagagaa atgtcattgt tacttagaag accaccagga cgtgaggcat atcctggaga
    82741 tgtattctat ttacattcaa gattacttga aagagcagct aagttatctg atgaattggg
    82801 tggaggttca atgactgcct tgcctataat agaaactcaa gctggtgacg tttctgcata
    82861 tataccaaca aatgttatat ctataacaga tggtcaaata tacttacaac cagagttatt
    82921 ctattcaggt gtaagaccag cagttgaccc tggtatatca gtatcaaggg ttggtggttc
    82981 tgcgcaaatt aaagcaatga aaaaagttgc aggaacatta aaacttgcat attcacaata
    83041 tagagaactt gcagcattct cacagtttgg ttctgactta gatgaagata ctaaaaagag
    83101 acttgctcaa ggtgaaagaa tcgttgagat attaaaacaa ggtgagcatc aaccaataaa
    83161 agttgaaaat caagttatga taatatatgc tgttataaat aatcatttag aggatattcc
    83221 gatagataat atagctagat ttgaatcaga attgtatgca tttgtagata ataattatcc
    83281 ggaaatatca agaaaaatat taggtggaga agacttcact catgatttaa cagatgcaat
    83341 aaatgaattt aaagaaaagt ttgttgttga agtataatcc tttttaaaaa aggaggtaaa
    83401 ttaattggca ggagctggaa tcaaagcaat caaaacacgt atgggaactg ttgaaagtac
    83461 aaagcaaata actaaagcaa tggaattagt tgcatcttct aagcttagaa aagcaaaaga
    83521 aaaggctgaa gattcaagag aatattttaa tactttatac aatacagtaa aagatattgc
    83581 ccaaacaaca cgtggaatta gaaatgaatt tttaaaagaa agagaagtaa aaaataaatg
    83641 ttatgtagta gtagctggag acagaggact tgcaggtgga tacaattcca atgtattaaa
    83701 ggaatctgtc tctcatatga aaggtaaaaa ggaaacagtg attactgttg gaaagaaagc
    83761 acatgaattt ttttctaaaa gaaactacaa tatagcaaaa gatataaata gtgttgaagc
    83821 ttgtggatat gaagatgcga cagaaatttc acaaactatt attgacctgt ataaaaaagg
    83881 tgaagtagat gaagtttata ttgcttatac aaaatttaaa tctgctttat cacaagaagt
    83941 tgaaattttg aaattgcttc cattagtctt tgaaaaagat acagacgaac aaggaatggc
    84001 agtaaaagaa gaaaaacaaa atagatcaaa agtacaatat ataccatcag cagaagcagt
    84061 tttaagttat attgtacctc agtttatatc aggtacagta tatggtggaa ttttggaatc
    84121 ttttgcatca gagcaaggtg ctagaagaac tgcaatggaa tcagccacag acaatgcgaa
    84181 tgaaatgcta tctaatttag agttaagtta taacagagca agacagtcag ctgtaactca
    84241 agaaataaca gagatagttg gtggagttga agctctaaaa tagggaggtt aggaaatggc
    84301 aaatgtaggt aaagtagtac agattgtagg agctgtacta gatgttaagt ttgatagtga
    84361 acaaagccta cctaacttat taaatgcgtt agtaataaag ttaggagata aagaaatagt
    84421 tgcagaagtt gctcaacata taggtgatga tactgtaaga tgtatagcta tgagtgcaac
    84481 ggacggactt gtaagaggta tggaagttgt agatacagga gggccaataa gtgtccctgt
    84541 tggagatgag actttaggta gaatattcaa tgttcttgga aaaccagttg atgggaaacc
    84601 agctccaaaa tctgcaccta aattacctat acatagacca gcaccggcgt atgatgaact
    84661 agaaactaca gcagagatac tagaaactgg tattaaggta gttgacttac tagctccata
    84721 tctaaaaggt ggaaaaatag gtctatttgg aggagcagga gtaggaaaga cagttctaat
    84781 acaagagctt ataaacaata ttgctaagca acatggtggt atttctgtat tttcaggagt
    84841 aggagaaaga acaagagaag gtaacgacct ttatggcgaa atgagtgagt ctggagttat
    84901 aaataaaaca gctctagtat ttggtcaaat gaatgaacca cctggagcga gaatgagagt
    84961 tgctttaact ggacttacaa tggcagaaca ttttagagat gagcaaggac aagacgtttt
    85021 acttttcgtt gataatatat tccgtttcac acaagctggt tcagaagttt cagcacttct
    85081 aggacgtatg ccatcagctg ttggttatca gccaacatta gctactgaaa tgggtgcact
    85141 tcaagagaga ataacatcaa ctaagaaagg ttcaataaca tctgttcaag cagtatatgt
    85201 accagcagat gacttaactg acccagcacc agctacaaca ttctctcact tagatgcaaa
    85261 aacagtttta tcaagacaaa tatcatcact gggtatatat ccagcagttg accctcttga
    85321 atctacatca aggattcttg accctagtat agtaggaaaa gaacattatg aagtagctag
    85381 aggtgtacaa tcaatacttc aaagatataa agaacttcaa gatataattg ctatacttgg
    85441 tatggatgaa ttatctgatg aagataagtt aatagttgca cgtgctagaa agatacaaag
    85501 attcttatct caatcattca cagttgctga gcaatttaca ggaaatccag gtcaatatgt
    85561 tcctgttaaa gagactgtaa gaggatttaa agaaattctt gaagggaaac atgatgactt
    85621 accagagtca gcattcttat ttgtaggaac aatagaagac gctgttagaa aagcgaaggg
    85681 aagtatgtag tcatggccag tgaattttca ttgaaagttg taactccaag taatactttt
    85741 tatgatggag atgttgaaat gatagtagtt agaactacaa aaggagacaa aggggtgttg
    85801 aaaggtcata taccatttgt ttcaggtata cctgtaggaa ctttaaagat aaaaaaagag
    85861 ggaagtttta aagaggcgaa aatagcagaa ggattcatta atgtaactca agataaaact
    85921 gtcatattga cagaatctgc tgagtggatt taataaatta atttagagta taaaaagtca
    85981 ttttgaccaa aaaaactttt gggtaaaatg gcttttttgt gttttggtgt taataaaata
    86041 acgataaaat tgtaagtttt tagtgataat aaattcacaa aatgtttaaa tttactgcca
    86101 aattatgttg taattaataa gataaagaag atttagatag cttttatgta agtgaaaaag
    86161 tcttcatata agaaatacat ataaaatttt tataaaattt aaaaaatttg cttagttgtg
    86221 tagtataata aataatataa tagatttgta tataatattc attacaaata attttaaaag
    86281 ttacagtttt attataatga ttattaaatt aagataagta acataaacta aataataatg
    86341 tgtattatcg atagtaaatt tataaattca ttattaatta ttgaaagaag tattataaat
    86401 tttctggagg aacaatgaat atatttgata ttggcgtaga tataattgaa attgatagaa
    86461 taagaaaggc tgtagacaaa aataataggt ttttggagaa gatatttaca gatagagaaa
    86521 tagagtattt taattctaag aattttaaag cagaaagtat agcaggtaat ttcgcagcca
    86581 aggaagctat aagtaaatct ataggtacag gaattagatt gtttaatttt aaagatatag
    86641 aagttctcag aaatgaaatg ggaaaaccaa tagtaaaaac ttataataat ctagcaaaaa
    86701 tgtgcataga ttataatgtt ttagaaataa aagtttcaat atcacattca aaagattatg
    86761 ctatagcaaa tgcgataacc ataattaagg actaaggagt gattacatta tgatggataa
    86821 aacagcaaaa gaaataatga caacagatgt aatagtagca aaacaagatg atagtatagc
    86881 agatgtagct aatatgctaa ttgcagaaaa aataggaggt ctgccagttg tagattcaga
    86941 gaatagagtt gttggaataa tttctgaaac agatattctt aaaaaagaaa aatatataga
    87001 agcacctctc tatataaatc tattacaagg attgattttc ttagatgact taaaaaaagt
    87061 tgaaaaagat ataaaacaag tagctgctta taaggttgga gaacttatgt ctaaagatat
    87121 aataaaggtt catgaagatg ataagtttga tgatgtagct aatgtaatga ttaaaaaatc
    87181 aataaacaga gttcctgtag tagatgatga caacaaactt aaaggtataa tttgtagata
    87241 tgatataata aaagctttat acaatgaata aactgaagta ggaggtgtga tgtgagaaaa
    87301 aagtggacca tagtatgtat tatgttcttg gcactggtta taattgtaat aggatgccaa
    87361 aaacgacagt ccacaaaaga agaagtatac aaagattttc aaaagcagat ttctgatatg
    87421 aattattaca gttgtaaagc tgaagtagaa gtagttggaa ataaaagccc acacaattat
    87481 gttttaattc atacttataa aaaaaccgat aactataaat tagaagtaat ttccccaaaa
    87541 catttaaaag ggaaaagtat agaatatcaa ggtgataaaa tattagttaa aaatccaaag
    87601 attagtgatg tagtggagtt acctaataca ggaaaaaata atcaatatct ttttgtagga
    87661 gactttataa aaaactatct tcaaaatgag gagatgaaag taaagttatc caaaggacat
    87721 ttggttttag agacttttat tcctggggat aataaatatt ttaacaagca agtattatat
    87781 gtaaatgctg acacaaaaaa tcctgaaaaa atggaagtgt tagataaaga gggagtgcca
    87841 agatttacag taaaatacaa agattttgaa tacagaaact aagggggact aaagacatgc
    87901 aaaaaataac agtgcctaca tgggcagaga taaatctaga taacttaaga tttaacttaa
    87961 ataatattaa aaatttatta gaagaagata ttaagatttg tggagtaata aaagctgatg
    88021 catatggaca tggtgcagta gaagttgcaa aattgctaga aaaagaaaaa gtagattact
    88081 tagcagtagc aagaactgct gaaggaattg aacttagaca aaatggcata acacttccta
    88141 ttttgaactt gggatatact ccagacgaag cttttgaaga ttctataaaa aataaaataa
    88201 ctatgacagt ttattcttta gaaacagcac aaaagataaa tgaaattgca aaatctttag
    88261 gagaaaaagc ctgtgttcat gttaaaatag actcagggat gactagaata ggtttccaac
    88321 ctaatgagga gtcagtacag gaaataatag aattaaataa attagaatat atcgatttag
    88381 aaggtatgtt tactcatttt gctacagctg atgaagtaag taaagagtac acttataaac
    88441 aagctaataa ttataaattt atgtctgata aattagatga ggctggtgta aaaatagcta
    88501 taaaacatgt atcaaacagt gcagctatta tggattgccc tgatttaaga ttaaatatgg
    88561 taagagcagg aataatatta tatggtcatt atccatctga tgatgtattt aaagatagat
    88621 tagaattaag accagccatg aaattaaaat caaaaatcgg acatataaaa caagttgaac
    88681 caggtgtagg aataagttat ggactaaaat acacaactac aggtaaagaa acaatagcta
    88741 cagttccaat aggatacgca gatggattta ctagaatcca aaaaaatcca aaggttctta
    88801 ttaagggaga agtgtttgat gtagttggta gaatatgtat ggatcaaata atggttagaa
    88861 ttgacaaaga tatagacata aaagttggag atgaggttat actatttgga gaaggcgaag
    88921 ttacagctga gcgtatagct aaagacttag gaactataaa ctatgaagtg ttatgtatga
    88981 tatcaagaag agttgaccgt gtttatatgg aaaataatga gcttgtacaa ataaacagtt
    89041 atttgctaaa ataaaaccat gatattataa tctgggaggc gattttgtgt acgataagag
    89101 taaagaaaaa atagaagtta ctttacctga ctctctgatt tctgaagttg atagtatagt
    89161 tcagatggag aacagtaaca gagaagattt tgcaaaagct gcttttcagt tctatataac
    89221 tcagaaaaag aaaattcata ttaaagaatc tatgaaaacg ggttatagag aaatgggtca
    89281 aattaatctg tcactagctg aattaggtat gacagttgaa gaagtatctt ctgatgataa
    89341 aaatgaaggg aagattgccc aaggtgagta ctaattgtga aataaagcgt ggtgatttat
    89401 attacgctga tttaagtcca gttgttggtt cagagcaggg aggcgttaga cctgttctga
    89461 taatacaaaa tgatgtaggt aataaatata gtcctacagt tatagtatca gctataacat
    89521 ctcagattaa taaagccaaa ttacctactc atgtagagat aagttccaat gaatatgggc
    89581 ttaataaaga ctcagtaatt cttttagagc aaattagaac tatcgataaa aagagactga
    89641 gggaaaaaat tggttgtcta gatgaaaata tgatgataaa agtagatgat ggacttcaaa
    89701 taagtttagg attgtttact ttttaaagag ggatttgtct tttattagac aatccctttt
    89761 ttcttttaaa tatctcttaa ggtttaattt taatgtacta tgttaataaa attaaaaata
    89821 acgcaaaaaa atagcataaa agtgatataa taatatggaa ttgatataaa attacgaact
    89881 caagggaggt aattgcatga gagaccataa aggattaaat gagattgcgc gtatcataag
    89941 aagagatata gtttcaatga tacatagagc caaatctgga catccaggag ggtcattatc
    90001 agtagttgaa atacttactg cgttatactt tgatgaaatg aatgtggatt cttcaaatcc
    90061 taaaatggag gatagagata gatttgtatt atcaaaagga catgctgcac cagcattata
    90121 tgctacattg gctgaaaaag gctattttga taaggaagaa ctgaatggat taaggaagat
    90181 aggaaggatg ttacaaggtc atccagacat gaaaggcacg ccaggtgtgg aaatatctac
    90241 tggttcttta ggtcaaggtt tttcagtagc atgtggtatg gctatggcat caaagttgga
    90301 taatgctccg tggaatgtgt atactttgct tggtgatggt gaggttcaag aaggaattgt
    90361 ttgggaagct gctatgagtg ctgcacatta taaacttgat aatttaattg cttttttaga
    90421 taataatgga cttcaaatag atggagatat agaaagcgta atgagtttag gttcaatagt
    90481 tgataaattt aaagcttttg gttggaatgt aattgagata gatggacatg attttgacca
    90541 aatatttgcg gctcttgata tagctaaatc aacagttaaa aaacctacaa tgatagttgc
    90601 aaaaactata aaaggcaaag gaatatcttt tatggaaaat caagcaggat ggcatgggac
    90661 agctccaagt gatgaggagc tagaaaaagc cttgcttgaa ttaggaggtg ctgacaatga
    90721 gtaaaatggc gacgagagaa gcatatggta aagcattagt aaaattaggt caaataaatg
    90781 acaatgttgt agtattagat gcagatttat caaagtctac aaaaacacat gatttttaca
    90841 agtcatttcc agatagattt tttaatatgg gtatagctga acaaaattta ataggcgctg
    90901 cttgtggatt atcaactgct ggtaaaatac cttttgcaag tacttttgct atgtttgcta
    90961 cgggaagggc ttttgagatt ataagaaatt cagtttgtta tccaaagcta aatgtaaaaa
    91021 tatgtgctac tcatgcaggt cttactgttg gagaggatgg agcatctcat gaaagtgtgg
    91081 aagatattgc tataatgaga gctataccaa atatgacagt tcttgttcca gctgatggag
    91141 ttgaaacaga aaaaattatt tttgaaatag ctaagtataa tggacctgtt tatgttagat
    91201 tagggagaag ttcagtacca gttttatttg atgaagatta taaatttgaa ataggaaaag
    91261 gtacagtctt aagagaagga aaggatgtat caattatagc ttgtggaatt atggtaaatg
    91321 aagctctatt agcacaagaa aagttgcaag aagaaggtat aaatgctaga gttataaaca
    91381 tgtcctcgat aaaacctata gacaaagatt taatattaga atcagcaaaa gaaacgaatg
    91441 ctattgtaac tgtagaagaa catagcataa ttgggggatt aggttctgct gtaagtgagg
    91501 tagtaggaga gtcttgtcca accattgtaa agaaagttgg aattaaagat acatttggag
    91561 aatctggtac tccaaatgaa ttgttaaaaa aatatgaatt aacttgtgat gacataataa
    91621 agactgttaa agaagctatt attgcaaaaa gaatgtaaga gatataaatt attcatgttt
    91681 gttaataata taatatattt aaaagagagg tataaagtgt tatattaatt tatatctctc
    91741 ttttttttta tatgatatca atatatcaaa aatgtaataa aatattcaaa tttttacaaa
    91801 aatagagaaa atattcaaat atatattgac tattcagaaa aatatgacta atatataatc
    91861 tatagagaaa ctaattttat atataatgac tacttagata aaagaatcta aaaaaattat
    91921 gagaggagga gtagggtata aaatcagatt ataagtttta agttattata ctaaaaagct
    91981 ataaaacagt tatcatgtat tttatgttaa aggaaattgt aggtagttta tcgaattgtt
    92041 taatcagaag aaaaaatttc acatggggag gtaactgaga tatgtcagaa aaagtaaatg
    92101 ttaaaacagt catcagtttc gcaggtgcgt atgtagcaac agtaatcggt tctggatttg
    92161 caacaggaca agaaataatg caattcttct ctttttatgg ttttgcaggt attattggtg
    92221 ggataatttc aatggtatta ttctcatgga tgggtgcttc agttatgtca aaaggtaaag
    92281 agcttcaact taaagaacct atcaaaattt atcgtgttta ttgtggtaag tatttaggga
    92341 tattctttga atggtttgga cctttattct tatttggtgt tttcgtagta atgatttcag
    92401 gagcaggagc aactttaact gaatactatg gattaaatcc atttgtaggt agagtaggta
    92461 tggcagtagt agcattatta actgtttcac taggtcttga taaattatca aagatactag
    92521 gtggaatagg gcctataata ataatcttta cacttttagt tggtggtata agtttagcta
    92581 aaaacatagg taatatagga gaagctgcac aagttcttag cactgtaaag atagctaaac
    92641 cagttccaaa tgcctatcta tctggtgtaa tatatactac ttataacaca attgttgtta
    92701 tggcattctt aactggatta ggagcaagtg ctgctaacaa aaaggaagct atttgtggtg
    92761 gtatattagg tggagtagca cttatggctg cagctataat gatgcactta gctattcttt
    92821 ctgatatagg aaacttatat tcaaaagcaa taccatcatt attcttagca gataagattt
    92881 caccagtaat tggagtttta ttctcaataa ttcttatatt aggtatatat acaacagctg
    92941 tacctttatt atggtcagta actaatagat ttgtagatga taaacatcct aagtttaaat
    93001 taataacttt aatagcagct atattaggtc ttataggtgg cttcctacca tttgataagc
    93061 tggttggtat tttatatcca tatactggat atatgggcgt cataatactg gtttgtgttc
    93121 tttatagaca gattacaaaa acatctggat atcaagaagg aatcagtgac aaataagtat
    93181 tttttaatat tgtaaactca agagctatat gaaaacaatg aaaatgtttt catatagctc
    93241 tttttatttt ttagctcgtt tattatgaaa taggaaaaac atgtttttta gttacattac
    93301 atatatttat aattatggat aaatatatac taatcaataa tttagagtct aagataagct
    93361 tataaatcat atatttagaa tatatgggag gagtgataag attgaatgta aaatttaata
    93421 ttaaaggtat aatttatgga gttatagctc ttgtattcgt tataggggga tttatattca
    93481 taccaagtat gtttgtagag aaatctaaac ccatagatta tacagtatta caaagaaatt
    93541 caataccaga aaagatatta gatgtgatgg ataagtatac aaatgaagaa agagcattag
    93601 cggctaaaat cgataacaaa atatacatta tagtgactag aggaaataat aaatatggta
    93661 tagaaatgga caaaatagaa agtgtggttg aggaaggaaa ggatgttttg agagtcaaga
    93721 taaagtataa agataaggaa gattcttttc catacatagt tgttgaaaca aatatgagtg
    93781 aacttccaga tagaatagaa ttaaatgcga cgaaataaga aggtatttta taattaaata
    93841 actgcatatt gtacattaaa gtcatggttt ttattaatgt aagtaaattg tatatggttc
    93901 ttattgttgt aaaagccatg acttaaaatg cttataaagt aagatattaa cagtagtatt
    93961 tattactata ttaaatgggg tctggaaata cttaatgttc taattatttg gagtgataat
    94021 tctagtttca gtaactatgt agtctaattg tgcatcatga gtttcttttg gaatagaatc
    94081 gaatatctgg aagtcaaatg ctatgccgat agttatagca tcttttctta agttttctaa
    94141 aaatctatca taaaatcctc caccatatcc taatctatag caatgtatat catatgctac
    94201 agctggtaca attacaacat ctaaggcctt aatatcaatt gtaggtgatt tttcgttagg
    94261 ttctcttatt ccatatgctc caattctcaa tccctctttt aaatctgtta tttgagtagg
    94321 gattaatgta tgattttctt ttattgtgat gggacttgat actattttct ttagagacaa
    94381 aagttttttg attaaattat ctgtttgaac ttcattgtta aaatttagat aaagcattat
    94441 attagttgca tttcttatat cttccatttg aagtaatttt tcagttatta aatttgaatt
    94501 actaagtaca aagtttgcac tcttattttt tcttgattca ataacttttt ttctaaattc
    94561 ttttttcata aaataattcc tcccttaata tgttataatg tgtacagcaa ttgtatttaa
    94621 tataaatttt agtataattt attgtaataa agcaatatat ttgggtaaat gtaataaaaa
    94681 taacagctag tcatataata ataatagttt atgtaaaagg agatgtatct tgtgatttca
    94741 aagaagaaag ctattttttt aggggtgatt ttagtaatta taacagctat ggttacatca
    94801 gcatttcagt tgacattggg gaataaagtt gtaatatcga aagaactcta tgaagactat
    94861 aaaaaatatg ataagttgtt aggactagaa tctattataa aacaagattt ttataaaaaa
    94921 gtatcagata ctgatttggt aaatggagcg gcaaaaggtc tatttctagg aacaaatgat
    94981 aagtattctg gttattatac taaagatgaa atggagaatc taattaatga tagtgaaggt
    95041 tcttatgttg gtgtaggtat gtatataggg gcatcaaaag atggtggatt agtagtagtt
    95101 cccatgaaag attctccagc agagaaagca ggtgtaaaat caggggataa attagtaaaa
    95161 gtcaatggaa aatctgtctc atataaaaat tcagatgaag ctgttcgtat gatgaagggt
    95221 aaaaaaggga aaacagttga actgactata ttaagagaag ataaacaatt taactttaaa
    95281 gtaaaaacag accagataat tgagaagagt atagaaagta aagtaattga taatgattta
    95341 ggatatatag aaattaccca atttatatca agtacatata ctgactttga taaggcttta
    95401 aaagaattac aagcaaaaaa tatcaaggga ttagtaatag accttagaaa taatcctggt
    95461 ggaatgctag atatatgtaa agaagttgct gatgagttaa ttggtgaagg aactatagta
    95521 tatacaaaag ataataaggg aaatactgag tacttgaaat ctgataaaga aaaattggga
    95581 cttccaatag tagtgttaac taatggagaa agtgcttctg ctgctgaaat attaacagct
    95641 gcaatcgttg ataataaaga aggtatttct gtagggacta caacttttgg taaagggttg
    95701 gtacaatcag ttgtaagatt gaaggatgga acaggataca agttaactac tgctcaatat
    95761 tttacaccta atggagatta tatcaatgaa aaaggcataa agcctactat tgaagaaaaa
    95821 gatgaaaata aacagttaga tgtagcgact aaatggctta gagaacagat tgataaataa
    95881 agtttaattt ttataaactt atattgtaaa ataaagaacc ttaataaaag gagtgtctca
    95941 aaattaactt tttagtttat gaggcactct tttgtgggtc tttaaaataa agtgtgtatt
    96001 cttctaaaaa gtggtgataa ttaaaatatt aaatatcact atatataagg aaggtgcaca
    96061 ctttttatgt ttaacaaaaa cgaaatatta aaaaaactta ttgaagaata tgatgttaaa
    96121 acaactacag atattcaaga tatgctaaaa gatttatttg caagtacaat tcatcaaatg
    96181 ttagaagcgg agcttgacga ccatttaggt tatgatagat atgacaataa gaataaaaat
    96241 actaaaaact ctagaaatag atatagaaat aaaaatgtta aatcagattt tggagaaata
    96301 actttaaata
//
LOCUS       DACTZW010000003        92485 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.003, whole genome shotgun sequence.
ACCESSION   DACTZW010000003 DACTZW010000000
VERSION     DACTZW010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 92485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 92485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..92485
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.003"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            162..545
                     /locus_tag="JAM15_01075"
     CDS             162..545
                     /locus_tag="JAM15_01075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAT6796865.1"
                     /translation="MNLSKKIEDKRKAKQRAEKVKKAKIATAGVVLGAVTGAVSGVLL
                     APKSGKETREDIKDASQQIAEKINMKTVDVKGKVSEKLEDKKGNFIESKKKIKKYIDN
                     KKSVENSSEEDKIIDIVEPVSVTEE"
     gene            547..897
                     /locus_tag="JAM15_01080"
     CDS             547..897
                     /locus_tag="JAM15_01080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796866.1"
                     /translation="MDNTITINISIIYVLLAILACIALVYLIIVLVKLHKILNNVGTM
                     LNENTQNINTTLNNLPNVVETFGEVGENMKDVTEVVTEVTADFLVTKDSVKSNMDVIV
                     DILTIIKNIFLYKK"
     gene            complement(991..1449)
                     /locus_tag="JAM15_01085"
     CDS             complement(991..1449)
                     /locus_tag="JAM15_01085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796867.1"
                     /translation="MIRTKVVELIATVCRENKPHKWVDENYTPYDKSGKVELMSIEDL
                     NELISSSGRADFLYSSRLQKLLKEVYINQSRASYISGCGLFWSSYWDILEEKFEEWLY
                     NSYIFFDEDDEYLEGMEDFELECKDVLMDVIETTSIDIYVQMIKRNITNY"
     gene            complement(1494..2282)
                     /locus_tag="JAM15_01090"
     CDS             complement(1494..2282)
                     /locus_tag="JAM15_01090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAT6796868.1"
                     /translation="MKVVIIPGHTLIGKGTGAVGYINESKETRILNDLIVKWLKTGGA
                     TVYTGRVDESSNHLADQCAIANKQETDLAVQIHFNSNATTSTPVGTETIYKTNNGKTY
                     AERVNTRLATVFKDRGAKSDVRGLYWLNHTIAPAILIEVCFVDSKADTDYYVNNKDKV
                     AKLIAEGILNKSISNSQEGGENKVYENVIVYTGDADKVAAQILHWQLKDSLIIEASSY
                     KQGLGKKVYVVGGEANKLVKGDVVINGADRYETVKLALQEIDKL"
     gene            complement(2421..2858)
                     /locus_tag="JAM15_01095"
     CDS             complement(2421..2858)
                     /locus_tag="JAM15_01095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dCMP deaminase"
                     /protein_id="HAT6796869.1"
                     /translation="MNKKLENRCSWQEYFMRLCETVAERGTCDRAYVGAIIVNSENRI
                     VSTGYNGSISGDKHCSEVGHEMRDGHCIRTIHAEQNALYYCAKEGISVKDCSIYVTHF
                     PCLNCTKAIIQAGIKHIYYRTGYRIDEYAIKLLQSSNVLYTKL"
     gene            3680..4189
                     /locus_tag="JAM15_01100"
     CDS             3680..4189
                     /locus_tag="JAM15_01100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6796870.1"
                     /translation="MLSENIKTIRKSKGLSQQELAIKLNVVRQTISKWEQGLSVPDSD
                     MLISISEVLETPVSTLLGETIVESEVDSLKVISEKLEIINLQLAQRKNMRRKMFHWLF
                     ILLCAVILIVFVVLGGLNSPYLDWNYTDPETAVFGVAFHAFEWIFVRLVPIVLIGAII
                     GIFLTRKKI"
     gene            4594..5130
                     /locus_tag="JAM15_01105"
     CDS             4594..5130
                     /locus_tag="JAM15_01105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HAT6796871.1"
                     /translation="MQGGVNIRQIKSFVFPVISLIFLDQISKVLIGLFLMDFEIDIIG
                     KFLRFNPVQNTNLSYGGNFIGILSNLWVLVLFNILVILVIISGYAFYKSKNEQTSYSV
                     KVIMSCGLAGTICSLIDKLFWGGSLDFLQIPSFFIFDLKDCYLTVAEIIFVVIGILHN
                     REISMKEYIYFCYRQFKR"
     gene            complement(5551..6351)
                     /locus_tag="JAM15_01110"
     CDS             complement(5551..6351)
                     /locus_tag="JAM15_01110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6796872.1"
                     /translation="MRLNKRSEGYINYVKGVKREKRNVLFYQLLILIGFIVIWELLAD
                     LNVINTFLFSKPSDIYNLFIQYAFSGQLFKHIGISVYETVLGLVIGTVLGILVAIALW
                     WSEKLSKILDPFLVVLNALPKTALAPIIIVWVGAGIEGIVVTAVTISVVVTILSAYNY
                     FMNIDEEKIKMLKSFGATKSQILFKLILPANTGNLINLTKINIGMAWVGVIVGEFLVS
                     RYGIGYLIVYGSQVFKLDLVMMGVFVLAICAWAMYAVVNIIEKIYNSR"
     gene            complement(6546..8144)
                     /locus_tag="JAM15_01115"
     CDS             complement(6546..8144)
                     /locus_tag="JAM15_01115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAT6796873.1"
                     /translation="MKAAIYSRKSRFTGKGDSIENQIQLCIDYAKSIGVKDFLIYEDE
                     GFSGSNIDRPQFKKMMQDAKDKKFSYLVCYRLDRISRNVSDFSTLIEKLNELSISFIS
                     IKEQFDTSTPMGRAMMFISSVFAQLERETIAERIKDNMYELARSGRWLGGNTPHGFNS
                     EKITFLDENLKERSMYKLQVNDEQMEIVKLIYNKYLELRSLSKLYKYVYNNGIRGPRG
                     GKFDPSSLSRILRNPAYVKANDEILDYLKNSGMDVVGTPDRKCGILTYAKNTSNSIAA
                     IAKHHGVIEPEIWLEVQNQLDKNRDKTPRISTGKTALLSGLIKCGKCGSNMRITYKGK
                     KTDKDLKYYYICGTKKTLGSDSCNCKNLNGPLVESLVIDKIKNCKEESIISAFNSNNI
                     KTDNVFNIFKSETNLLKNQILDKERLIKNLVIELAKNTGSTASDYIVFQIESLNNEIS
                     ILKDKINTLESSNINISSDSINIDIIVSNLKRFNDEVDNASLDDKRLLLSTIINSIIW
                     DSSLGNLNIVYMGAEVDNSVSLSN"
     gene            8822..9952
                     /locus_tag="JAM15_01120"
     CDS             8822..9952
                     /locus_tag="JAM15_01120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HAT6796874.1"
                     /translation="MNNFEIKTRIKFGEGSLKVLQELKNKNVLIITDPFMVKSKTIDK
                     ITSNLINSTYQVFEEIVPDPPIEVVVAGIEAFKSINPDVIIALGGGSAIDAAKSIMDF
                     SKKILKINEVEFIAIPTTSGTGSEVTSFAVITDSQKKCKYPLVSDDLLPDMAILDPEL
                     VKTVPNFITADTGMDVLTHAIEAYVSTNSNDFSDALAEKSIKLVFKYLIKAYKDGNDI
                     EAREKMHNASCLAGMAFNQASLGINHSIAHVLGGKFHIPHGRTNSILLPHVIEYNSSI
                     VGYTNTTYSDTAKKYAQIAELVGLGSANIRISVRNLVNEIKKLQKEMNMPTKLTQCKL
                     SLEDITNEEREIAKLAIKDTCTLTNPKVPTEDDIINILNNIK"
     gene            10193..10543
                     /locus_tag="JAM15_01125"
     CDS             10193..10543
                     /locus_tag="JAM15_01125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003453843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HAT6796875.1"
                     /translation="MTEESKQRVIQEYVPGKQVTLAHIIANPNEDIYKKLGLVLDKRD
                     AIGILTITPSEASIIAADVATKASNVSLGFIDRFSGSVVISGDVSSVESALNDVLEVL
                     GNMLNFSSTKITRT"
     gene            10551..11000
                     /gene="eutP"
                     /locus_tag="JAM15_01130"
     CDS             10551..11000
                     /gene="eutP"
                     /locus_tag="JAM15_01130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutP/PduV family microcompartment system
                     protein"
                     /protein_id="HAT6796876.1"
                     /translation="MKNIIFMGKTGSGKTTLCQKLDQLELKYKKTQSVELYNNAIDTP
                     GEYMENRNLYNALITTSADAKIIAIVYDATQEENYIAPGFASMFCKDVIGIITKINKA
                     TENEVNIAYERLSLAGASQIFKIDTVDNIGLEKLFKYLEKSKNIDEV"
     gene            11102..11677
                     /locus_tag="JAM15_01135"
     CDS             11102..11677
                     /locus_tag="JAM15_01135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAT6796877.1"
                     /translation="MGKKILLVDDEPLLRMDTKDILESHGYEIIGEASDGFEAVEMCK
                     KHKPDLVIMDIEMPILDGIKAGKIICKENLAGGVLLLTSFEDKEYVEKAKSIGAYGYL
                     VKTASEKSLIPTIEMCLNKVNEFEKMKKDLEKVNSKLNERKLVERAKGILIREFKISE
                     DEAYTRIRKLSMDKRTTMMEIAKMIIIGYDD"
     gene            11670..13079
                     /locus_tag="JAM15_01140"
     CDS             11670..13079
                     /locus_tag="JAM15_01140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HAT6796878.1"
                     /translation="MTNTIKKISTAQTYLNNNEIEKIIEVSKSLDLMASFYEADVFID
                     VLSKFDDEAIVVAHGRPKEKSMYCENVIGKKALIENEPGVIKCLKTGERVRDIKALTQ
                     EYKLVKQNIQPITLDDKVLAVLIVEKDISSEVKNEFNASEDEENKNLHQFIKLIGNND
                     FLVDNLNSAILIFDKNGKLKIKNRIATEIYKNLGFGYDIQDMHYNDLDIETNTFENIL
                     MDENYDETNEVSIGNMFFKIKTIYIKDDEFKVCKIVQDISDLKRKEEELVLKTVAIRE
                     AHHRVKNNLHTVISIIKKQSRLSQNDEVKQCLDNIINRVFAILSTHYLLSKEVDNNIS
                     IREGINLLVSNIQGGYLFSKDIDIRITGEDFKISGEKATAILLVINEILQNCYDHAFS
                     DREHGTIQILINKDNDYRNIAIIDDGIGFDSNNINKNSLGTYIIDSYITQMLKGNIER
                     KSNENGTEVLITIPTQINI"
     gene            13263..14696
                     /gene="eutA"
                     /locus_tag="JAM15_01145"
     CDS             13263..14696
                     /gene="eutA"
                     /locus_tag="JAM15_01145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004458698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase reactivating factor
                     EutA"
                     /protein_id="HAT6796879.1"
                     /translation="MREELLSVGIDIGTSTTQLIFSKLIVENTESNFSVPRISIVDKE
                     IIYKSKVYFTPLISNNEINGQQIKDIVENEYKKANISKEDIHTGAVIITGETARKENA
                     NDVLHTLSGFAGDFVVATAGPDLESIISGKGAGAHIYSKEHSTTIVNIDIGGGTSNIA
                     SFKRGEVTDTGCLDIGGRLVKIDKISKKITYISPKIDKIIKDNNLNLQVGTMATVENT
                     KPIVDIMVDLLMESIGLKKQTPLFDFIITNKSISIDENIKNVSFSGGVADYIYYDGEI
                     KDYFEYGDLGILLGQAIKNCEYLKKVNVVKSMETIRATVVGAGSHTTEVSGSTITYTS
                     EKFPLKNLPVLKLSVDEETGTSKQISEAIKNKLNWFKLENDLQKVAIAMIGKKNPTFL
                     DIQEYAKGFVDGMQQIIENDLPFIVIVENDMAKVLGQAIYALLNYEKEIVCIDSVKVE
                     NGDYIDIGKPIVEGKVLPVVIKTLVFN"
     gene            14714..16078
                     /locus_tag="JAM15_01150"
     CDS             14714..16078
                     /locus_tag="JAM15_01150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003454054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutB"
                     /protein_id="HAT6796880.1"
                     /translation="MILNTKLFGRTYQFKGLYDVMAKANEEKSGDKLAGLAAESAEER
                     IAAKVVLSHIKLEDIRNNPAVAYEEDEVTRIIQDAVNEKVYEEIKNWTVSELREWLLD
                     SNTTSLDIKRISRGLTSEMIAAVAKLMSNMDLVYAAKKIKVTAHCNTTIGEQGTLSAR
                     LQPNHPTDDPDGILASLLEGLTFGIGDAVLGLNPVDDSVESVTKVLKRFEEVKQKYQI
                     PTQTCVLAHVTTQMEAIRNGAPADLIFQSIAGSEKGNEAFGFNGDTIEEARQLALKHG
                     TATGPNVMYFETGQGSELSSEAHHGIDQVTMEARCYGFAKKYEPFLVNTVVGFIGPEY
                     LYDAREVVRAGLEDHFMGKLHGLPMGVDVCYTNHMKADQNDMENLAILLTTAGCTYFM
                     GIPHGDDVMLNYQTTGYHETASLREMFGLTAIKEFDAWMEKMGFSKDGKLTELAGDAS
                     VLLG"
     gene            16091..16972
                     /locus_tag="JAM15_01155"
     CDS             16091..16972
                     /locus_tag="JAM15_01155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutC"
                     /protein_id="HAT6796881.1"
                     /translation="MNEKDLKALVEQLVGQMVGELDTNVVSETVEKATEVVVDNNACI
                     DDITEVDIRKQLLVKNPKDAEAYLDMKAKTPARLGIGRAGTRYKTETVLRFRADHAAA
                     QDAVFSYVDEEFIKENNMFAVETLCKDKDEYLTRPDLGRKFSPETINNIKSKFGTNQK
                     VLILVGDGLSSAAIEANLKDCVPAIKQGLKMYGIDSSEILFVKHCRVGAMDHLGEELG
                     CEVICMLVGERPGLVTAESMSAYIAYKPYIGMAEAKRTVISNIHKGGTTAVEAGAHIA
                     ELIKTMLDKKASGIDLK"
     gene            16992..17645
                     /gene="eutL"
                     /locus_tag="JAM15_01160"
     CDS             16992..17645
                     /gene="eutL"
                     /locus_tag="JAM15_01160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003461990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutL"
                     /protein_id="HAT6796882.1"
                     /translation="MKNDVIRPNILGIKIISNISPEMAQKLELKSHHKSLGLITADCD
                     DVTYTALDEATKASEVDVVYAKSMYAGAANASTKLAGEVLGIIAGPSPAEVRSGLNAV
                     VDFLEYGATFISANDDDSIAYYAHCVSRTGTYLSEIAGIREGEALAYLVAPPLEAMYA
                     LDAAMKAADVKMCELFAPPTETNFGGALLTGSQSACKAACDAFAEAVKSVADNPTGF"
     gene            17656..18357
                     /locus_tag="JAM15_01165"
     CDS             17656..18357
                     /locus_tag="JAM15_01165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HAT6796883.1"
                     /translation="MDAIGLIEVIGYVAAIEASDACLKSANVNIVRIDKVGAGIVTLT
                     ICGDVGAVKAALEAGEIAASRVGTLRTSHIIPRIHNEVTNALFKTKEPKVCEVSEDKE
                     KNFEITLEITDNVSKNLSEKENVILDVNENSGYTENLYSDIDKTNKKIETVDDSLTEA
                     NEEKIENTNDKEVLEQVKIENSDFDRDDLSKNSVKKLKAMAKKLDSSITYKDLNVLKK
                     EELINLVKKLSRRDR"
     gene            18360..19829
                     /locus_tag="JAM15_01170"
     CDS             18360..19829
                     /locus_tag="JAM15_01170"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetaldehyde dehydrogenase (acetylating)"
                     /protein_id="HAT6796884.1"
                     /translation="MTLLDKDLVSIQEVRTLVRRSKVAQEKLSKMSQEQIDKIVKAVV
                     DAAFNNATKLAKMANEETGFGKWEDKVIKNTFASMGVYETLKNTKTIGIIGEDKEANT
                     IDIATPVGVVAGLIPSTNPTSTVIYKTIISLKAGNTIVFSPHPNAKNCILETVNIISE
                     AAIKAGAPEDSILCITNPSIVGTNELMKHKDTNLILATGGEAMVRAAYSSGTPAIGVG
                     PGNGPAFIDKSANVKLAIKRIIDSKTFDNGVICASEQSIVIEKSMEETVLKELKNQGA
                     YVLNEEESERLAKFILRANGTMNPQIVGKSVEVIANLADLTNVPKNTKVLVARENKVG
                     HNVAYSREKLTPILAFYVEENVEAIMNRCREILLNEGAGHTFSMHVNDEELVKRFALN
                     MPVSRILVNTPSALGGIGASTNLVPALTLGCGAIGGSSTSNNIGPLDLINVKRVAYGI
                     KEIEELGRDKSQVEKSMFDSMDKEELINLLVQKLVKELA"
     gene            19925..20212
                     /gene="eutM"
                     /locus_tag="JAM15_01175"
     CDS             19925..20212
                     /gene="eutM"
                     /locus_tag="JAM15_01175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutM"
                     /protein_id="HAT6796885.1"
                     /translation="MASANALGMIETKGLVGAIEAADAMVKAANVQLVGKEQVGGGLV
                     TVMVRGDVGAVKAATDAGAAAAERVGELISVHVIPRPHFEVDAILPKVSAE"
     gene            20339..21100
                     /locus_tag="JAM15_01180"
     CDS             20339..21100
                     /locus_tag="JAM15_01180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin adenosyltransferase"
                     /protein_id="HAT6796886.1"
                     /translation="MGVLTENEVKRKIGKNKNNITEFYIEKGQIITPSAKSYLAERSI
                     ELKYVDKLSDVNNKPKEVVKEVVKEKKYKYTTVFGAKLDEKPEHMTQLNGNLLVFKDH
                     KRIILRGKIDSLESEILKVQILCQKLDMPKLVKELQEVLDFVRNIMRCEVLDEKLGDF
                     KLLGLTPQELREQSHYPKKYFGIGHEFPSYEMGEVVVAINSIRSNTREVELAAYEAFK
                     GEYGNVHREDLIKALNRLSSVFWIMIYKVRTNKYK"
     gene            21113..21742
                     /locus_tag="JAM15_01185"
     CDS             21113..21742
                     /locus_tag="JAM15_01185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HAT6796887.1"
                     /translation="MENLLNEIVEEVITRVKKEAFIEVEASGRHVHLSREDVDKLFGE
                     GYTLTKLKDLSQPGQYACKERVTITGPKGSIKNVVVLGPCRNETQVEISLTDGSTLGL
                     KAPIKQSGDLEGTLSIKISTQYGEVELDKGLMVAKRHIHMTPKDAEKFNVCDKEIVEA
                     KVMGQRPLTFDDIVIRVSDSFKTYMHIDYDEANACGYSKGTVAKIIKKA"
     gene            21784..22509
                     /locus_tag="JAM15_01190"
     CDS             21784..22509
                     /locus_tag="JAM15_01190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein"
                     /protein_id="HAT6796888.1"
                     /translation="MNYDNLVDLITEEIYKKINSNEIKISNKPKAVIVFKQDNNKFNL
                     LKDEFEIVEFDKSIRECEIVIVSRLCMRGLSNIALGNSTSDEERFILKMIMKGKKVYV
                     LDEGIEYKKYKDTAPKALYKKFMSFEDEICKFGVEIIKDLNVITKNKLNIKKELESTR
                     GSKKEDTKVLDKDVLNLTSVESVKIDNEFSLDLRNKKLISEADLRKPTINGVKNILVN
                     KKSIITPLAVDFMRIHHLKLKKL"
     gene            22522..22794
                     /locus_tag="JAM15_01195"
     CDS             22522..22794
                     /locus_tag="JAM15_01195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutN/CcmL family microcompartment protein"
                     /protein_id="HAT6796889.1"
                     /translation="MDIGKVVGNVWATRKDEKLCGQKLLVVKILKTKDTYKEGFMVAA
                     DNAGAGNGDLVLISKGSSARESIEKSHVPVDATIVGVVDSFEVFDE"
     gene            22787..23338
                     /locus_tag="JAM15_01200"
     CDS             22787..23338
                     /locus_tag="JAM15_01200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HAT6796890.1"
                     /translation="MNKSIGAIEFKSIAKGIEVSNEMIKKSSVDVLYLKSICPGKFLI
                     IVGGETSYINECVDYGIKLGEGYIVDNFVINAISQEILDGFKNKYQKLDSIVSIGVVE
                     SSKVCAGIKMLDKTLKSGDLVLVKLQLSFAIGGKLVYVVAGDLSSLEYALKESENVVR
                     EKEVIYKTVIPSVDSQIIKSLIK"
     gene            23350..24441
                     /gene="eutH"
                     /locus_tag="JAM15_01205"
     CDS             23350..24441
                     /gene="eutH"
                     /locus_tag="JAM15_01205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HAT6796891.1"
                     /translation="MSINEIIIYVMVVFMVLGAIDKCIGNKFGLGEQFEEGIMAMGSL
                     AVAMVGVICLAPVLADVLRPIVVPVFNILGADPAMFAGSLLANDMGGAPLALELAKDP
                     NAGLFGGLIVGAMMGPTIVFIIPVALGIIEKEDQKFLATGILAGIITIPIGAFVGGLV
                     AGFEVMMVLRNLVPIIIFAVIIALGLLKFENAMIKGFTYFGKGVVIVITLGLAAAIVE
                     ALTGIVVIPGMKPISEGIEIVGDIAIVLAGAFPLVFVITKVFNKPLMALGKVLGMNDV
                     SAAGLVASLANCIPMFGMMKDMDNRGKIINVAFSVSAAFVFGDHLGFTAGFNSNMITP
                     MIVAKLVGGITAVLLAMVIANKTLRKENV"
     gene            24443..24916
                     /locus_tag="JAM15_01210"
     CDS             24443..24916
                     /locus_tag="JAM15_01210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF861 domain-containing protein"
                     /protein_id="HAT6796892.1"
                     /translation="MDISNIDKNLIETLVRQIIGEKISGTKDTVDFVRNKDISGITSI
                     KLPTVKVSESDRLDTGNPSDVVYTKDLFTLEESPRLGCGMMEMKETTFDWTLNYDEID
                     YVIDGTLDIIIDGRKVSASSGELIFIPKGSKIQFSVPDYARFIYVTYPADWASQN"
     gene            complement(25036..25137)
                     /locus_tag="JAM15_01215"
                     /pseudo
     CDS             complement(25036..25137)
                     /locus_tag="JAM15_01215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433047.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
     gene            25432..25953
                     /locus_tag="JAM15_01220"
     CDS             25432..25953
                     /locus_tag="JAM15_01220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAT6796893.1"
                     /translation="MEEIVKKEQASMNDIFLYLKAKSNSLYKFVILYNEFINKPKDYG
                     TGELINMVEVHMLTAIEENPGISPTQLAKIWNRTKGAISQTISKLEKKGYITKEKKEG
                     NAKTILLYPTTSGVELSKAHKLYDTIDVTRTFEYLIKECTLEEIDSFYKVIDLFINLL
                     EESPQENNDSEKV"
     gene            26332..27507
                     /locus_tag="JAM15_01225"
     CDS             26332..27507
                     /locus_tag="JAM15_01225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HAT6796894.1"
                     /translation="MNLKQLSEKYEEYVIQMRREFHKYPELSFKEIRTTQRIREELQK
                     IGIPFVSIEPNIVIATIQGKNEGKTIAIRGDIDALPMQEDSDVEYKSEYDGIMHSCGH
                     DAHGAMLLGLAHMLNDIRKDLKGRVLLVFQAAEEVGGGHKEIIQYFKENGGPDRLIAT
                     HVWSDIEAGKISVEPGPRMAGGSGWRIDITGRGGHGSRPDQSIDPIKPACDIVLKVSS
                     IPVNHISVLEQCVVHACAIHGGTTIGNVIPNNAEVIGGYRYFTEESGKKVFDIIKQMS
                     NGVGQAYGVDVKVTHTGGIGPVINDEESVKMAKEIVSNIDGLELDSYKPICASDCYGE
                     ILKEYSGFYCYLGVGNKEKGIIYAQHHPKYNIDEDTLKLGCEFMAKYAVEFLNKNNN"
     gene            27541..29079
                     /locus_tag="JAM15_01230"
     CDS             27541..29079
                     /locus_tag="JAM15_01230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HAT6796895.1"
                     /translation="MQGALKENKKKSGGGFLGWIERVGNKMPHPLALFTYITFIVVAL
                     SAIASFLGFSATSPATGKLIKVMNLISAKGLVLFMQEFVKNFQNFPVLGVVLVMAVAT
                     GVCEKTGFFSTAIKMSLSKVKGNAVVFIIAFIGVFANQAGDAAFVLVPTLAGAIFYGL
                     NRNPLAGIFCGFASVGGGFATAVIPGGWDVTLTPITVSAAQTIQPAFDMTLLASYYAL
                     FVSAFIVATVSTIVTVKFIEPKLGKYTGKPEGIDDNQGFEVTKEQAKAAKLAGFTVLA
                     YVALLIALCIPANSFLRSPEGSLIFGAPLMSCLQFFIVILFFLPGIVYGMRVGKIKTV
                     KDLNDILCQSMAAMAPFIVLAIVIGQFLTLFSVSNLAQVLAIKGGALLNSLPLQPQVI
                     ILLFLVLVAFINIFVISGSTKWMIFGPVFVPMLMQLNIHPAFTQFVYRLGDSVTNHLS
                     PLNAFFIILLATVQKYDKNAGMGTIFSAMIPYTIGYFVVLAVLVVVWMTIGIPVGIGG
                     QVWL"
     gene            29111..30313
                     /locus_tag="JAM15_01235"
     CDS             29111..30313
                     /locus_tag="JAM15_01235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAT6796896.1"
                     /translation="METTEIRYNFDEVIDRSGTNCLKYDLKSQFMPESPEDALPLWVA
                     DMDFACAPEIINAMHERIDRKIFGYSSQQTDDYYEAVCGWFKRRFDWKIEKENIFFSP
                     GVVPALGFFTQILTQKGDGIIIEKPVYYPFEDKITNNERKVVNSPLKFEDGHYSMDYD
                     GFEELAKDENNKVFILCSPHNPVGRVWKKEELRKIVDICKKYDLWIISDEIHCDIIRK
                     SEKHIPLEVACPDYKDRIITCTAPSKSFNLAGMQLSNIVINNKELQEKWMLETDSKLA
                     IFLPNPFAIVATKVAYNDCEDWMNQVNEYIDGNIKYVEDFVNEYMPKVKIIKSQGTYL
                     IWLDFRGYGLDAKQLEYVMLNKAKVLLDEGYIFGEEGAGFERINVASPRTIIEECMNR
                     IKCAFEGL"
     gene            complement(30492..31091)
                     /locus_tag="JAM15_01240"
     CDS             complement(30492..31091)
                     /locus_tag="JAM15_01240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAT6796897.1"
                     /translation="MNDNIVEVKNINMNFYTKEGELEVLKDVNFNLKEGEILTLLGPS
                     GSGKSTILNILTNLLKPTSGDIKITGNIGYMFQKDNLLEWRNIMDNITIGLEIQGKKD
                     KKSLDRVESLLKTYGLWDFRSMYPKELSGGMRQRVALIRTLSVNPDILLLDEPFSALD
                     YQTRLLVCDDVYSIIKNENKSTILVTHDIGEARCIKVQL"
     gene            31260..32618
                     /locus_tag="JAM15_01245"
     CDS             31260..32618
                     /locus_tag="JAM15_01245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796898.1"
                     /translation="MSNIITNLIESVFTNPITILFLLAITVYSVFKIIENNRVYSFVS
                     SKLDEINRDYKTSEFYKKVRDDYYTYSKENPYADVNITSFIEEVVSDLKHNNLPLLEK
                     IRSIKNSSSISILLGVLGTFVGLSTMLLCVDTKDIINSLPSTISSMQTAFTTSIFGVV
                     FSLIIGYFTKIKDCEHVLIQIMLKSENLLTSEITHFKSERMDLKVEEVKNTIKQISKS
                     IEAIEKFDKISKDLNDFNDEFISGIEALKSLLEGSQSSIKTFDQSVRKLDKQFNILNI
                     KFVKLFDKYDNQDNINKEILFDIKESSKNIYNATESQFKIRDYIKNINAGFALYERSA
                     QDLLTKLMTHENKISQNQKILLDEKFTLDDSIKNLSSIIENFSNDLQIKLDMMFENSL
                     DIQDKLDVMFNNSFMNDEVPLDSEELFKDDVNNVFNPFSEEIYEIEDKEIKVIGEDEL
                     NE"
     gene            32611..33243
                     /locus_tag="JAM15_01250"
     CDS             32611..33243
                     /locus_tag="JAM15_01250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HAT6796899.1"
                     /translation="MNNKYRRTVNREFEKSSFWPTFTDLLSTVLMVVILILFSSESIS
                     GSVEQDLAKNVNASVEETFKKSKIPVKVDKSNGQVTFGEKTMFDVDSDVLKPEAKEML
                     KMFVPKYIETIYKDYGDYISKIVIEGHTDDVGSYIYNLDLSQRRAYSVAKFIVGDEIG
                     DYKYKDKVTKHIIAIGRSKAELIKNGDNSVNRDASRRVELKYEININQNK"
     gene            33572..34729
                     /locus_tag="JAM15_01255"
     CDS             33572..34729
                     /locus_tag="JAM15_01255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAT6796900.1"
                     /translation="MIEISIKNKKNSKIKTLILLLIVSISIYLTGCTTSDNGNNQSNN
                     NDSLSSSISSDKNVKIHFIDTGNSDAILIQDGKTFTLIDGGDNDDEGLMVDYLNNQGV
                     KDIKYLIATHSHADHLGGLDSVVKNFNIENVFVSNGSAETKSYRDFINALANKGLSPS
                     VPLENNKFYLEDSYFEVLNTNGGDTTNEQSLVLVYTNGNDKVLFTGDAEEGTEKEILP
                     KLEKVDLLKVAHHGSRSSSSQEFLDKVNPEYAVLLVGKGNSYGHPHQETMNKLKKMGV
                     KVHRSDECSDIIFESTGDGVFTSCKDGSYNKGVREDGNSGKSNSNTSKNDSFKNKQNT
                     FNSEEIVYFTPKGKSYHSIKNCSGLSRSKKILSGTIEESKKNDPCDICYGK"
     gene            complement(34877..35512)
                     /gene="lexA"
                     /locus_tag="JAM15_01260"
     CDS             complement(34877..35512)
                     /gene="lexA"
                     /locus_tag="JAM15_01260"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HAT6796901.1"
                     /translation="MYLDLTEKQVLILEFIKSQITLKGYPPAVREICTAVGLRSTSTV
                     HSHLNKLEKLGYIRKDPTKPRAIEVLERSKVNDVSGANQEIIELPLVGQITAGEPILA
                     QQNIEEYIPFPASLVKGSNNFVLRVKGESMINAGILDEDYVVVDKKNTALNSQIVVAL
                     INGESATVKRFFKEGNLIRLQPENDFMEPIMLNDSEVEIVGIVTGVFRVIK"
     gene            complement(35616..36743)
                     /locus_tag="JAM15_01265"
     CDS             complement(35616..36743)
                     /locus_tag="JAM15_01265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HAT6796902.1"
                     /translation="MNNDKKIIKVHNKSDKPDNIVIKENELIEKCLLLENKLPVFMKD
                     YFIYLKGSVAVSTRLAYLEDINFFCSYLIETKELTNADCVKDITEDDFNTIKSRDINL
                     FLGDYCSRYYKNTEKNTLIFENNNRALARKKSSISTLFKFLYRNSQIDNNITDGFNPI
                     KLPKPQPDAIKRLEIDEVAKMLESVETGEGLTEKEKVYWRKTKLRDKAILALFVTYGL
                     RLNELRELNISSFNFSRGEFKIYRKRGKEVLMPINHTCEHVIKDYLQNERTRDELLND
                     EEKDALFLSLQNKRITAKAIRTLVKKYTSIPLDTTRDNGYSPHKLRATAATSLIQTGF
                     SIYDVQNLLDHDNVTTTQLYAAHKKNVKRDIVKNFEWIEDD"
     gene            complement(37065..37910)
                     /locus_tag="JAM15_01270"
     CDS             complement(37065..37910)
                     /locus_tag="JAM15_01270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796903.1"
                     /translation="MIYIIEILKISVINIFCFIGIFIVFGLIFSITENLNNKFIFSSF
                     GKTGIIVTGAIGTFVHELSHLIMCLIFMHKINSVKFFRPIESKNDGILGYVSHSYKKD
                     NLYQSIGNFFIGIAPIIGGTIMIILIFKILLPDSYMKVTQNIDLKLYVSMINNLNING
                     FIHIILGDISNFIRIMLLTPSVYSLKYFIFMFLMYSISTHMSLSSADLKNSLNGLSFI
                     VIVIFVISSITYLFGFDNLNISSLILKYNIFISFFMAIGFIFSIVTLIISYILSLVSP
                     FKNFS"
     gene            complement(37940..38311)
                     /locus_tag="JAM15_01275"
     CDS             complement(37940..38311)
                     /locus_tag="JAM15_01275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HAT6796904.1"
                     /translation="MKLKLLVEEYAVCRLNNDSKIPTWIDTEKLYSITRTDDELSVVC
                     LNNNIPSDVKSEKEWRILKILGPLDFSLVGILSKLSSLLADNKISIFAISTYDTDYIL
                     VKEKDIENACKILSCNGYEVE"
     gene            complement(38464..38724)
                     /locus_tag="JAM15_01280"
     CDS             complement(38464..38724)
                     /locus_tag="JAM15_01280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003866776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein S"
                     /protein_id="HAT6796905.1"
                     /translation="MEVLKVSSKSNPNSVAGALAGVLRERGVAEIQAIGAGALNQAIK
                     SIAIARGFVAPSGMDLVCIPAFTDIEIEGDKKTAIKLIIEPR"
     gene            complement(38913..39857)
                     /locus_tag="JAM15_01285"
     CDS             complement(38913..39857)
                     /locus_tag="JAM15_01285"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit alpha"
                     /protein_id="HAT6796906.1"
                     /translation="MIENNSEKIKVLENDIKQLITISKANNIDLSDKINSLNEKLEKL
                     KEDAFSHLSAYEKVTLSRDIKRPTTLEYIEHICSNFLELHGDRLFKDDPSMVGGIGQI
                     GKFNVTIVGHQKGRDTKENIKRNFGMPHPEGYRKALRLMKQAEKFNRPIITFIDTSGA
                     FCGLEAEERGQGEAIARNLLEMSKLSVPVITFVIGEGGSGGALGIGVGNDVCMLEHSV
                     YSVISPEGLSSILFKDSSKAKEACDVMKLTSNDLYDLKIIDKIIKEPLGGAQKDVEAV
                     SKEIKAYILERLNHYKDMDKEEIIAQRYKKFRNIGKCL"
     gene            complement(39878..40732)
                     /locus_tag="JAM15_01290"
     CDS             complement(39878..40732)
                     /locus_tag="JAM15_01290"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HAT6796907.1"
                     /translation="MIKKFLSSKESKYVTISLDDNFKKNSVDDKFWTYCKGCDSHVFR
                     KDIEENSFVCPKCSRHYGLRARKRINLLIDKGTFMEFNSDVEFQNPLNFPKYKEKVDS
                     YKEKTKESEAVVTGYGRINGIKTVICVMNPDFMMGSMGSIVGEKITYSIEYAAENNLP
                     IIICSASGGARMQEGMVSLMQMAKTSQALSKLEEKSLPYISVLTDPTTGGVTASFAML
                     GDIIISEPNTLIGFAGPRVIEQTINQKLPEGFQTSEFLLEKGFIDMIVDRRKMKELLY
                     QILAMHKK"
     gene            complement(40747..42108)
                     /gene="accC"
                     /locus_tag="JAM15_01295"
     CDS             complement(40747..42108)
                     /gene="accC"
                     /locus_tag="JAM15_01295"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HAT6796908.1"
                     /translation="MIKKILVANRGDIAVRIIRTCKELGIKTVAIYSEIDKDCFHRYI
                     ADESICIGPNNISKSYNNIENIIYLALKLKCDAIHPGFGFLSENPEFAKQCEDNNIIF
                     IGPTREQMILMGDKSRARETMMELNIPVVPGSESVLKTKEEALEVAREIGYPVMIKAS
                     SGGGGKGMRIVRKEEELFSNFDMASSEALAAFSNSDLYMEKFIENPRHIEVQVFGDKH
                     SNAIHLGDRDCSMQRRNQKVIEESLSPYLSDEERQKLHKIAVDIVKGVGYIGAGTIEF
                     IVDKDKNFYFIEMNTRIQVEHPVTEMVTNLDLIKLQISIANGEEIPFKQEDIAFRGHA
                     IECRINAEDSSNNFAPSPGKIESLNLPGGFGVRFDTFVYAGYTIPPLYDSMIGKLICW
                     AETREECINRMYRALDEIIVEGINTNVEFQKALVTSEEFREDTHHTKFIEDVFMKKEF
                     ATL"
     gene            complement(42124..42576)
                     /gene="accB"
                     /locus_tag="JAM15_01300"
     CDS             complement(42124..42576)
                     /gene="accB"
                     /locus_tag="JAM15_01300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HAT6796909.1"
                     /translation="MNINEIKELLKAIDSTNLEYVKLESSDLRLEVSKKAQSTSSPVL
                     SVQQESVVDLSLEKPVVNDTPVTSNENLSVVVAPLMGTFYDSPSPDADSFVKVGDVVE
                     EGDTLCILEAMKLMNEITSEIKGEIIEVLVSNEELVEYNQPLFKIKPL"
     gene            complement(42846..43292)
                     /locus_tag="JAM15_01305"
     CDS             complement(42846..43292)
                     /locus_tag="JAM15_01305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796910.1"
                     /translation="MESKFFNWYTQSLGGTFGIISCICAYLNGYMFVYTNSASKYFES
                     IGFLGIISSYTLLPLCMLTLIFGVIYSYTPETSDKSIFNIPFFTLNKRLILITVVFGF
                     IGARVYFIIPAILITFNLYSNVLIAKLKYILCKNKENDTNLKESEV"
     gene            43567..43845
                     /locus_tag="JAM15_01310"
     CDS             43567..43845
                     /locus_tag="JAM15_01310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796911.1"
                     /translation="MVDTLEFGLKILFFILSIIWMGKIMILRTDKQIVINPLLIGISA
                     VLVMLHTSQSNIEFFGLDVQYIRIVLYIIYSLIILIGIWATNRRNGIF"
     gene            complement(43974..44705)
                     /locus_tag="JAM15_01315"
     CDS             complement(43974..44705)
                     /locus_tag="JAM15_01315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796912.1"
                     /translation="MNLANLIPFIISAAALSPINSNDKVLSENQLKDIFPDANLRAVV
                     KRYINPDEMTISNIKALDGEFYATGESISNLKGISYLENVDNFIFWNNNIKEVPKEAL
                     SLKDMDSINLANNYLIDDDVVNSLSHNGVDVNCDLNFIDTKDNQYKLDSKYHNVDIAK
                     GESIDLRKIITKKIDSYYKYWEVTDNLPKDLNFIVSVSDKSVLSCEDMIIKGNKTGQA
                     VVKVILSDKNDLNTSQEVLITVNVK"
     gene            complement(44849..45493)
                     /gene="trmB"
                     /locus_tag="JAM15_01320"
     CDS             complement(44849..45493)
                     /gene="trmB"
                     /locus_tag="JAM15_01320"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HAT6796913.1"
                     /translation="MRRRRKKGADEKLLSYTKYVLRDDIDKSKGKWNLKFRNDNPIHV
                     EFGTGKGKFITTLAKQNPDINYIAMELKEEVLLKAVEKADASNLNNILFLWGDVSNIL
                     DYFEAKELSRIYINFCDPWPKNRWSKRRLTHSGFLEMYNRVLEDDGEIHFKTDNEKLF
                     EFSLNEIAANNWLLKNISLDLGNSEYENNVTTEYEDKFMSQGMRIFRCEAKKRN"
     gene            complement(45631..45951)
                     /locus_tag="JAM15_01325"
     CDS             complement(45631..45951)
                     /locus_tag="JAM15_01325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein HesB"
                     /protein_id="HAT6796914.1"
                     /translation="MKITLPETAIDTLKSILKDNQDKPNNIRVYFAGVGCGGPSFGLA
                     LDEKKEDDLTYEVGELQFVMSSDEYSQYGDIIIEDTGFGFRVIPENMKDQGGGGCSGC
                     SGCH"
     gene            complement(46402..46827)
                     /locus_tag="JAM15_01330"
     CDS             complement(46402..46827)
                     /locus_tag="JAM15_01330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012201185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HAT6796915.1"
                     /translation="MHDELKIKMYSFTMDCKDPHELAKFYAALLNWEIAFYNEEYACV
                     GAPGTNQGTYPGITFQRNSEYKPPVWPEKPESQQQMAHMDFAVNDLEEAVQYAIHCGA
                     TIAEEQFTDDWRVMIDPAGHPFCLCQMKSIMESSHFSLL"
     gene            complement(46980..47441)
                     /locus_tag="JAM15_01335"
     CDS             complement(46980..47441)
                     /locus_tag="JAM15_01335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HAT6796916.1"
                     /translation="MKFGGVLLIVKDINKSKKFYEDVMEQKITLDLGEHVSFENGFGL
                     QSNYKAIIGYDLPIYQQSNNFQLYFEVNDIKQWESKINRIGNIEFLHYIKEYPWGQRT
                     FRFYDFDKNIIEISESMESVIKRLLKQGLALEEISKRTMYPVEFITQFQQL"
     gene            complement(47479..48309)
                     /locus_tag="JAM15_01340"
     CDS             complement(47479..48309)
                     /locus_tag="JAM15_01340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6796917.1"
                     /translation="MLKKESIHFINNRSLIVCEDNFVYLLPCIQLRNWISNFTISFPN
                     QTIISDNYTIIPHGSVTLVFFYDATGLHSLLFGPTTKPKTVGNIANRCDVILIIEFQP
                     AGFFPLIGIQQSELIDKVVPFSIINTSLDLEIKKIFNESLSIDKLILKLEELLISNIK
                     IEYSYEFILAIQLIIQNSGNISSQEISKKVFYSSRHLNRLFNQYLGLSMKSFSRLVRI
                     NKSIKLLNNNKTSLMYICNELGFYDIPHFIKDFKIVCGITPQKYRANMSDFYSEIAKF
                     "
     gene            complement(48583..49269)
                     /locus_tag="JAM15_01345"
     CDS             complement(48583..49269)
                     /locus_tag="JAM15_01345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6796918.1"
                     /translation="MKITHNSLAVEAKNIIKEYKIGNTTTRVLKEVSLQVIKGEFVSI
                     MGRSGSGKSTLLYILGGLDTPTSGKVYMNGADISHFNDEKMSIIRRRNIGFVFQFYNL
                     IPNLNVEENIMLPLLLDGKNLKDYKNQLDEILDIVGLTDRRKHTPRELSGGQQQRVAI
                     ARALIGKPEILFADEPTGNLDSKTGIEIIDLLNKINRDNGQTIIMVTHSPDAAKSSSR
                     TITVSDGLIV"
     gene            complement(49284..51761)
                     /locus_tag="JAM15_01350"
     CDS             complement(49284..51761)
                     /locus_tag="JAM15_01350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAT6796919.1"
                     /translation="MKIILKYIFTNIKERKIRTAVMLLSLVLSTVLLFVSFSIGLSYE
                     SAQRKMAKGMYGTATISVQSKNPDILTNLEDIPDLNAIKSKVGVLESSAIYNKGGYYE
                     EFSLISADLSQLNKINKPRLENGDSITDFSGDKIILPNRFTSKYKIKKGDSITLQIYG
                     KSYTFQVSDIASYDTVFLRNTRGVNALLPKETLSKIINKGSGYTRVLIESEEEMTENL
                     VNKLSEELSTEKYMVSNTINETKIISDARQKTMPFFLISFFALTLSIFIIYSSYKVIT
                     LERLPFIGTFRSIGANEKTVTRILMLESILYGSIGGLIAIPIGVVVLNLMLHGLGNSL
                     EQGISIPVVISPIGVIISVIVAIIVSSFSAYIPVKKASHLPIKNIVLGTVEEKNVSNR
                     SILFIGSIMFILSILLPRISPENTLYLAGGFSLLGLIVATIVLIPLITDIMSIVFEFV
                     YKNILGNEGKLAARNMKNNKNIIQNITLLFISISAVIAISVVGNFVKTYITDVFRDAE
                     LQGFADGKMNEEFIEDVRHMDGIKKILPLYVMNNEISGNGVTLSRLEGTDNIKLYNSM
                     FGINYTNFEIKKQVIEAFNDKRSVILNEDTLKKVGLSIGDTITLSNDKYDFSYKIVGS
                     FKSRANDVEAVIPSHYAVNDFDKTNYGFLVYTAVNPDVVMIQIRYLFGDTYNWSRTVE
                     EFNNDSLNTISSFLSPMNKMTYFIFLLATVGIINNLLINYIQKRRSIAMYKSIGLSDK
                     QNIKVTLIEGFTSGLLGAVIGIVISILEIQTIFIVAGPKISMKPDLDFKTFIIVGLLG
                     IIVTLIGSIVPIIKGKKMKLIEEIKFE"
     gene            complement(51980..53383)
                     /locus_tag="JAM15_01355"
     CDS             complement(51980..53383)
                     /locus_tag="JAM15_01355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAT6796920.1"
                     /translation="MHKSSYKTVFHSYIIFFMIFICLILTVIGIFLSLITIQKPNGEF
                     IRSDWPKKFTENFNEQIIFIDNKPQVKQSGLEKLRENQLWLQILDSSGNRVYGFLEPK
                     EHKDYYSNSELLTLANQNNSSNGTVYFNTIKNNKNDYIYIIYFPLNISKVNMFFDGGK
                     FIGGKSIVFSIIGIIFLIILVSGIAYGYWITKCISNITSAVSDISKRSYLPVNIKGVF
                     ADIYNSLNILNEEIHKSDEIQNKTDIMREEWISNITHDLKTPLSPIKGYAELLTDSST
                     NYSPEKVYKYASIMLKNIEYTNTLINDLKLTYQLKNGIIPLNKNNYDLVRFLKELSID
                     ILNYPEYESNIVEFKSNIDNINFDFDCTLLKRAFSNLIVNAFTYGDKNTKVCVHITLN
                     ERIEIIISDNGKGMSREEASNLFNRYYRGSNTKQKIEGTGLGLAITKQIIEVHGGNIS
                     VESIPGLGSSFYITFPI"
     gene            53882..54742
                     /locus_tag="JAM15_01360"
     CDS             53882..54742
                     /locus_tag="JAM15_01360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAT6796921.1"
                     /translation="MKKQKSPILLEMLGLFFGCISMSIGINMFLKPHTIAPGGLSGLS
                     LVLNKVTGLPVSAIMLIIGVPLVILAFRIMGTKNSLKTLFGTVVFSAIVQLTDPLSKL
                     RFTNDLLLSSIAGGILVGIGLGIMFKSDASTGGTDLIALILSKKFPGIKATKFMSCLD
                     GMVVISSGIVNRSLETALYSGIALCVLIKIADMIMEGFDHSKAFFIISDEPESLRQAI
                     TEELDRGLTILDGKGGYTRENKEVLLVVVSKKQELYLKRLVKRTDPTAFVIVTDVHEV
                     LGEGFKNLEN"
     gene            complement(54982..55539)
                     /locus_tag="JAM15_01365"
     CDS             complement(54982..55539)
                     /locus_tag="JAM15_01365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAT6796922.1"
                     /translation="MSDSEYPQMKTLETRSCILRPASLDDVEDFFDCYKNKIVVKHLP
                     FSEHKSLEDTRKFIKSFFLNPYKKGKIGHFAIVYKRDNKVIGNMGFNNINPKALEAEI
                     GICINPSYWGHDFATEITKRVIQYGFRELNLNKIIAITYEENQNSTKSLDLLGFKCTG
                     KYIKKIHTGNTVKNVPCYQYELKKQ"
     gene            complement(55729..56616)
                     /locus_tag="JAM15_01370"
     CDS             complement(55729..56616)
                     /locus_tag="JAM15_01370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAT6796923.1"
                     /translation="MNIKLELYKVFNAVVNNKSFSLAAKELFMSQPAVSQSIKQLEEQ
                     LDTLLFYRNNKGVKLTPEGKILSEHVTTALKLISSGEDRINKFKKLEYGSLKIGVGDT
                     AARFFLLKYLEIFHKKYPHIHVSTINRTSRELISLLKDGNIDIAIINMPIEDDTLNIV
                     ECIEIHDIFVCANDYIEYKGRKISLEELNTLPLIMLENKANSRLYVNEYFLSKGIKLN
                     PDIELGSHELLLEFAYINLGVSCVIEEFSIDYLENEKLFKLDIKEPIPKRNIGYCHLK
                     DISLSLATKEFLSMISNNI"
     gene            56735..57934
                     /locus_tag="JAM15_01375"
     CDS             56735..57934
                     /locus_tag="JAM15_01375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003493023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F420-0--gamma-glutamyl ligase"
                     /protein_id="HAT6796924.1"
                     /translation="MDRLVGTVSRGVRAPIIRQGDDLVKIVVDSVLNASKSENFEVRD
                     KDVIAVTEAVVARAQGNYAHVDNIAKDVKDKFGDDTVGVIFPILSRNRFAICLKGIAK
                     GCRKVVLMLSYPSDEVGNHLISIDELDDKGINPWSDVLTEEKYRELFGYNKHTFTGVD
                     YVDYYKNLIKDCGAEVEIVFANNPKTILNYTTSILTCDIHTRQRTKRILRQNGAKKVY
                     SLDDIMTASVDGSGYNDQYGLLGSNKATEETVKLFPINCDEVVNKIQGNIKEITGKDV
                     EVMVYGDGAFKDPVGKIWELADPVVSPAYTKGLEGTPNEVKLKYLADNDFADLSGDEL
                     KEAISKYIVEKDNKSDDLTGNMVSQGTTPRRLTDLIGSLADLTSGSGDKGTPIIYIQG
                     YFDNYTK"
     gene            complement(58128..60683)
                     /locus_tag="JAM15_01380"
     CDS             complement(58128..60683)
                     /locus_tag="JAM15_01380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAT6796925.1"
                     /translation="MMSLVKFSIQYIKHYKKQSISIVLSIVLSVALLTGIGSLVHSAD
                     KSRIEKIREDSGDYHYFYKVDKEQLNKIKKNKKSKEYIVDRLGVTKPKNQIDEPFIIE
                     FLNADSSYLDMTGRKLLKGTLPSKDGEIVLDTYSLNNLNVNKEIGTEINLDSKIYKLC
                     GILSSLSNPETTMEGFVNDYLQPKEKDSYIVYVKYDENKNIKKQNYKFMKKFNISKEK
                     TYINWPLSVEFGVKPPKNIEKYNIFEFLKNLELNTNAIILLVGVFGAAAVYSIFHVSI
                     LQRISQYGVLEVLGANNKQLLFLLFLELFLLFIVGFPIGCFLGIGVASTIYEQFPHIF
                     LSSDIVPGAFFISEKSIYLGFLFILLLLILIAVRVVHQLNKYSSIESMKNFKITNTKK
                     RILESVKHSNMTKVLSHKYMTQKRGMFIGILFSLSLGGIIFLCSSYSIQLTKNNNELT
                     MKADDGLNSDYQITMQTTDFDVGIPKDKMARLNNVEGISKVYPVRYLFGAMQIKEEQL
                     FWKNFFKPLEKDYRIKTFFDGICTKQNEGGYLLKTNIYGYNNGMLEGLNSYIIDGEIN
                     THDMVKNNKVIVRLPMDGTGMYDAVDINPGDTIKVKVPKTMKPTGEIVKFKEENKNDY
                     TTKEFVVAATVKRVMANNIYFIGDYGMDIVMTNGQMKNNFDIENYNSVSIKKTEDSNS
                     EELSENIKSVVSDVKRCIVTDYTIAIEKNNTYLNQKLLFIYGIVFVLLAISLFHIINT
                     VSYLIFSRRHEFGILRAMGITDNKFLLMMIREGFLYGFYASIIMVIGSVIGQFMIYFM
                     VKRVYLYINPILKINTPLYIGMIILNITISIVAVIIPVRQILKSDIISEINKN"
     gene            complement(60680..61366)
                     /locus_tag="JAM15_01385"
     CDS             complement(60680..61366)
                     /locus_tag="JAM15_01385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6796926.1"
                     /translation="MSILVTNNLVKHYGKGETKVKALNGVSIEIERDTFTAIVGTSGS
                     GKSTLLNIIGGLDNPTSGDVIIKGKNISKIGKKDLTVFRRRNIGFIFQNYSLMPVLNT
                     YDNIALPVTLDKGNHIDHEYIEMLMKTLGIWDKRLKFPSELSGGQQQRVAIARALANK
                     PALILADEPTGNLDSKTTMEVVCLLKESSAKFHQTILMVTHNENIAQVCDSIIHIEDG
                     VVVNTGGEVL"
     gene            complement(61443..62351)
                     /locus_tag="JAM15_01390"
     CDS             complement(61443..62351)
                     /locus_tag="JAM15_01390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAT6796927.1"
                     /translation="MFILAFIICTVVIFIVSTKINQKRYDELSLMLNQILEGKEVTYP
                     DTKDTRASKISHQVKKIKDMIEIEVEQSKSEKEAIKGLISNMSHQLKTPLSNITIYCE
                     LLENINISTLQKKEFLQKMKNETFKIDWLLQSLFKMTKLEDGVIEFEVEELLIKDTLI
                     QSISTIFNKAEAKNIRINLEPFSDIKLVHNKKWTIEAIVNVLENAIKYSPSDSTITIS
                     VIKMELYTKITIKDEGIGIDSRELNDIFKRFYRSKNVENQNGTGIGLYLTRLILEKEN
                     GNIIVESKLGSGCCFSIFLQNCKSLN"
     gene            complement(62353..63024)
                     /locus_tag="JAM15_01395"
     CDS             complement(62353..63024)
                     /locus_tag="JAM15_01395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6796928.1"
                     /translation="MNLLIIEDDINLNEGLFYAFENDGFNVFKAYTKQEGLNIFNSKN
                     IDFVILDCNLPDGDGFDVCQIIREKSDIPIIMLTARDSEIDEVKGLEIGLDDYITKPF
                     SLSVLKARVKVAIRKKSNNKVIYSNGIKLDQKLLKVYKNKACLELSSVEYKLLSYLIE
                     NKGQILLKEQILHHIWDSEENYVDDNIVSVNIRRLRVKVEDDPSNPKYIKTAYGMGYL
                     WNEVE"
     gene            63286..64350
                     /locus_tag="JAM15_01400"
     CDS             63286..64350
                     /locus_tag="JAM15_01400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S ferredoxin"
                     /protein_id="HAT6796929.1"
                     /translation="MKRVDERNTMFARANYKKDSTAYNDYYKKNPDKKEIDDSIRNRP
                     NLCSEGTMTYNELNSPMASSAFDFLSDIKSLCEGKVSDTKVDVDAKSMTKKIKGLAKQ
                     YGASVVGITKLKDYHIYTNRGRHEENYGEEINLTHKYAIVFGCEMDKEMINRAPMICE
                     VIETSKCYVDASIVGMILSYYIRNLGYDARNHMDANYLVMPVFIARDAGLGDIGRNAI
                     LTNKDYGSRLRLGVVTTDIPLLEDEYVDFGLEDFCKVCKKCSFNCPSHSLSNDIKIGD
                     DGKYNWVIEHETCYIKWRYLGTDCGMCISACPFSQNLETIKNTTSFKGNNELIQKALD
                     EYTSKFGKRIFIPGNPSWLK"
     gene            64508..65194
                     /locus_tag="JAM15_01405"
     CDS             64508..65194
                     /locus_tag="JAM15_01405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6796930.1"
                     /translation="MEKILVVEDDSILNKTLSYNLIEDGYITTSKFTAKSALKSIFEC
                     EFDLIILDINLPDKSGFELCNEIKENYNIPIIFLTANDMECDMIKGYELGALDYITKP
                     FNINIFKQKVKAFLNHLTIKTKQDHYRDGYLEINFSELSANINGNQIIFTPLEYRTLK
                     LLTENPKSILTRKVLLEKLWDIDANFVDEHTLTSVISRIRSKIEKDNLKYIKTVYGMG
                     YMWLGERNEF"
     gene            65184..66215
                     /locus_tag="JAM15_01410"
     CDS             65184..66215
                     /locus_tag="JAM15_01410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAT6796931.1"
                     /translation="MNFKKFSFSSIYLIIAVGIIFTAILFNISIYLITDDLKLIALLL
                     IYTIVLCGFIALIIFLLHKKIVIFCSKICHTLDSMMNSEDNIEIELEEETILSRINHR
                     LIRMYEVIQENRNSIAIEKADLQELVSDISHQIKTPIANLKMINTTLLNQTFKTEIQK
                     DFLMDMENQLDKLDFLMQSMVKTSRLETGIITLSKKKNSIYETIATALSGILFDAEKK
                     NIEVTVDCDPNLYIIHDKKWTSEAIFNILDNAVKYTNSNGKIRVATECWVMYTKIDII
                     DNGKGISESHQAEIFKRFYREEDVHDIEGIGIGLYLSRKIISLQGGYIKVTSDIGKGS
                     TFSIFLPNK"
     gene            66297..67027
                     /locus_tag="JAM15_01415"
                     /pseudo
     CDS             66297..67027
                     /locus_tag="JAM15_01415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435295.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            67040..69457
                     /locus_tag="JAM15_01420"
     CDS             67040..69457
                     /locus_tag="JAM15_01420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6796932.1"
                     /translation="MFRNNNRTFIRKIALNDLKINKLKTYLSGIIIMISTCLLLTVSL
                     VSYNASVDLVNASPYHAIYKSVDEKAKNILYKDKNLSGVGTYKLIGSNKKTDCIMSIV
                     YADDTAIKLMNFQPLKGKLPTNKNEISISEKYLQEFGLDKDIGDSIKLNYYDDITNKE
                     VQCDFIIVGFLENYYQDNAKQYYTVVSNDYFKNIASTPLQNKSNTFDESRPDTVDVLV
                     KLSEENTEKDSASIKTQLKKIGLSLGIKKYNIYLNDNYIESNLIDGEQIITVLVVGIV
                     VLFSSVFVIYSIFYISVVNSVQMYAKLKSLGMTSFQLKKIISLQGNILSIIFIPLGVI
                     ASCIIAYIIQPLAWQMIADLFIILILSLVMFLTVRISLFKPARIISKISAIEAMQYTE
                     TKFRKKAKNFSYINIKNLALKNIESNRKKNLIALISLSISGVLFISIANLANSIDFKK
                     QLSQQFVYNEDYIISIKNDNLYEHITEIQQNNPLTDSLKNEIKSIHGVKKLIESKSIK
                     SNIIKPYIKDRDEKQFITLIKGITPELSKSLEEYIVSGKIDYTHLDSDSLIINKYRTK
                     SYGLNLKVGDTVTFNIFSGNDIIKKKMKIIGIIDNSNTGGMFFASDKTLESLTPYNTN
                     LDFSILIDKKHSKEVEEKLLSIIQKNSNLMLYSYEDDYRMITRAFQYIIIASYIFVGL
                     ISCFGILNMTNTLINSVLIRKKEFALLQAVGMTRKQLRNMLYREGLNISIKAICTSSI
                     LGYFGSNLLCTFIKDVIRLDFINFKFSIFTILIFSFVLIGIQVLVTELLVRNIEKKSL
                     TERLRSQ"
     gene            complement(69638..70429)
                     /locus_tag="JAM15_01425"
     CDS             complement(69638..70429)
                     /locus_tag="JAM15_01425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006567241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAT6796933.1"
                     /translation="METKQYLIDFYNTYDEDSRLALKHGMVEFLTTMHYIDKYIKSGD
                     CVLEIGAATGRYSHTLARQGYDVDAVELVEHNIEVFHKNTQSNENISITQGNAMDLSV
                     FPDNKYDITLLLGPLYHLYNKEDKQQALHEAIRVTKPGGVVFAAYVISDGCLIDEGFH
                     RGNINVSEYIEKGLIDPQTFAAKSEPKDLFELVRKENIDDLMSAFNVTRLHYVASDGL
                     ALYMREAVDSMDDDAFALYLKYHLATCEREDLVGVTSHAIDIFRK"
     gene            complement(70462..71049)
                     /locus_tag="JAM15_01430"
     CDS             complement(70462..71049)
                     /locus_tag="JAM15_01430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003505088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAT6796934.1"
                     /translation="MPPKVKITKEMILNTVLDITREVGFEAVNARSIASKLQCSTRPI
                     FTCYENMNELKNEFLAFAYEYYNQYVVNYRNSKSVSPYLLLPLSYIEFAQEETYLFKL
                     LFINDLDLMMKEANDFYKEIDNEKKARLFSESIGIELECAKVIFLDLFLYTHGIAVLT
                     ATKKLTLDRYSAEKMLKNILTAFIRQEKPDWNLSI"
     gene            complement(71226..72617)
                     /locus_tag="JAM15_01435"
     CDS             complement(71226..72617)
                     /locus_tag="JAM15_01435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796935.1"
                     /translation="MERLARREQPHIKFGMFKIRIPFIHYRFEKPEAIQGIISSMTSL
                     GTIGLSTQILGLPYEVAWSMAIINSILYCLHVFMGDPVVPGWITASITLTTAYLLKFS
                     MGIERIQALTALQIDLGIIFILMGITGVAGKLVSKIPNSIKGGILMGVGISTIISEFN
                     PKGRFDSYPISITVGILVACFVMFSERFDTLKVKNKFLFHLGEYGVVSAILVSLIVGI
                     FSKEIEIPRFSFDNLVYIVDFKNLINTVSPFGIGFPSVMLFIQGIPMAFMIYIIAFGD
                     FITGENLVLSESENRKDEYIDFNSNRSNVISGIRNIFMAIFSPYIPMCGPLAATLTGS
                     VAQRYKVGKEAMQSVFSGMGTLVWVSAIFICFYPIAQIATPLIPLALSVTLLVQGYLC
                     TKLSMELCNTGVEKGLIGLMGGVIAAKGGTWGLAVGFILYFILIDSKKRKEKDINSIE
                     DCVYEILDKKKSI"
     gene            complement(72807..74105)
                     /locus_tag="JAM15_01440"
     CDS             complement(72807..74105)
                     /locus_tag="JAM15_01440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HAT6796936.1"
                     /translation="MKVNVYNVESFVDERLKIMVSDLIPNTKLKISVKMEFPWCKGEE
                     FSSYGVFCSNEKGEVDLDLVEPIEGTYKADNCMGLIYSLEKSKTEGKNFAENISIDKP
                     IIMNMIFETSTERKEVELKRIFKSEDITTKYISDEFIGKLFYKQNSNNKTILMLGGSD
                     GNLDALDLLAAPLASRGFNVLTVAYFALEGLPDKLEEVPLEYFEKVFEWISENEITST
                     KEIFVHGTSKGGELAFLLASRYEQIKKVVVSQPHIYCFQALNGLMSGNDTSSWSYKGE
                     PFPYIKVDNDIFFEEQKKNISKGIPFGFNSTYKKSLKRAENRKEARIKIENSKADILM
                     IAGKEDNIWNSYEACLEALEIFEENNYPYNVELLTYNNMGHPLPIPYIMPLKETLCMS
                     MSGGIFSSGGTVEGNSKGQFESWNRTIEFYKKPLSSDLNN"
     gene            complement(74466..75341)
                     /locus_tag="JAM15_01445"
     CDS             complement(74466..75341)
                     /locus_tag="JAM15_01445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HAT6796937.1"
                     /translation="MITFDVNGAIIRFDDTKNNYNKIRKIFKLYALEISKNFERDCLN
                     SFQNLKQISDRGLSLGEKYIEESFKKGIETIVSFGIITIDIDTFKSVYCEKYLDFKRL
                     FNNLNKTFIIPNKNKKNGHASFLEIESTIKKMSNYLYNDCFKIHYAVVDALIENRITA
                     VHSYIDEESIKKSNALFNNYKDGFIGKADECKVVKQIITLNPYREDVYEFLVKEDGDF
                     SKEIERLTEFLGYDIKEYKASLMDIYINELMESDENDVENAKEKIEKYARYIGCSDEN
                     LYVARVNAIYTFANA"
     gene            complement(75534..76220)
                     /locus_tag="JAM15_01450"
     CDS             complement(75534..76220)
                     /locus_tag="JAM15_01450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HAT6796938.1"
                     /translation="MFGVIANSLAIAGGCIVGLIIKGGLPQRVSDTIMNGIALCVLYI
                     GISGALEGKNTLVTIISVAVGALIGELIDIDKWVNKLGAFLQSKFSKGNKKDSIAEGF
                     ISSSLLFCIGAMAVVGSLESGLTGSHDTLFVKSVIDGIASIIFTASLGIGVMFSAISV
                     FLYEGIICVGASFLNGFLSDPVVTEMTAAGSLLIIGLGLNVLKLTNIKVANLLPAIFI
                     PILFGVFGII"
     gene            complement(76269..76802)
                     /locus_tag="JAM15_01455"
     CDS             complement(76269..76802)
                     /locus_tag="JAM15_01455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HAT6796939.1"
                     /translation="MSDLNNKKEQDENESSMNETKIYDILDKLNVEYDVVEHEAVYTA
                     EQLVILDGITKGCQCKNLFLRNAKGNKYYLIVVKGEKQVDLNSLKDKIGSSRLSFASP
                     ERLYNVLKLLPGSVNPFSLINDTERKVELYIDKDVIKEDYLNFHPNINTKTVNISRKG
                     FEEFLEYLKYPIQSIDV"
     gene            complement(76846..77478)
                     /locus_tag="JAM15_01460"
     CDS             complement(76846..77478)
                     /locus_tag="JAM15_01460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
                     /protein_id="HAT6796940.1"
                     /translation="MKVFDLTHVTHNDMPVYAEPNRPDIKKVAIIEENGYQETLISVF
                     SHNGTHMDSPRHMYTKGETLDKLDIENFVGKAYVLELEKGNENIELEYLKKYEDEIKN
                     SDFIIFKSGWSKFWDKKQYYVGYPTLTKEAANYIANTNIKGIGIDMLSVDRYNTSVFE
                     VHHILFEKGKIIIENLTNLENVPEKFLFIAAPFKYNDADGAPVRAIAIVE"
     gene            complement(77568..78647)
                     /locus_tag="JAM15_01465"
     CDS             complement(77568..78647)
                     /locus_tag="JAM15_01465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796941.1"
                     /translation="MKIAIFLGAGASAAENLPIQNELFSEYFKKLNPTNYNTKMNREL
                     YIFFKQMFNIDIVKDNIDNANFPTFEEVLGLLDLAEQRKEAFRNFGLENLNNRSDSIR
                     FLRQYLILLMAEAIHNTPRTDNKYHKLLVENLLENDLLLDTTFISANYDIHIDNTVTG
                     LRDKNDLPIMLDYGVEFTNFKEELNWRKPKEPLIKLYKIHGSLNWLYCPICNSVTLTP
                     HEGGVMKLIENSSETKCLECGELTEPIIVPPTYFKNMSNIFLSNVWNETEKTLRDTDL
                     LIFCGYSFPEADMHIKYMLKRVQTNRKKPPLKIMVFNNHSQKQRITLKKEEGRYKRFL
                     GEDVIFTDNSFQDFSVNPLRFIKNI"
     gene            complement(78780..80126)
                     /gene="pepV"
                     /locus_tag="JAM15_01470"
     CDS             complement(78780..80126)
                     /gene="pepV"
                     /locus_tag="JAM15_01470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HAT6796942.1"
                     /translation="MKEQIKEKVNSLQDEMISSIQESVKIPSVISEATENCPFGENVD
                     KALRGILDLCKSLGFKTVYKDGYYGYAEIGQGEKMIGILGHVDVVPEGDLESWNYPPF
                     EAVLEDGKLYGRGTQDDKGPTISAIYAVKALMDLNVDFNKRIRFIFGADEENLWRCIN
                     KYKENNEEIPNYGFTPDSRFPITNAEKGLLQVHLTCDSKSDIELSVGKALNAVPGKAI
                     YIGKYSDKLKKELDKLNFEYTVEGNKICIIGKSVHSAASDTGINAVARLCIALNNIGI
                     DSNIIKFLAEVIGEDANGNNIIPNCKDDVSGKLTVNIGRVTIDNEKEFAGIDVRIPVT
                     YKKDDFVKELKKMTDKYNLNYEEYDFLDSIYVPEDTLLVKTLRKVYEEETGLDGTPLS
                     SGGATYARALDNCVAFGAIFPGKPETEHQANEYLIVEDIIKATQIYALSIYELLKI"
     gene            complement(80195..81475)
                     /locus_tag="JAM15_01475"
     CDS             complement(80195..81475)
                     /locus_tag="JAM15_01475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796943.1"
                     /translation="MLNETKELLKDYYGIDDDTFKLSQEIMEDIKDKFEEIKEIREYN
                     QYKVLKAMQESKLSDMHFNWTTGYGYNDIGREKIEEIYSKVFNTEDALVRPIIVNGTH
                     ALTLCIQGIVRPGDEILSVTGRPYDTLEGVIGIREEKGSLKEYGVTYDDVDFLEDGNL
                     DLEGIKNKINDRTKLVMIQRSKGYSWRKSLSISDIKEAIEVIKSVKPEAIVMVDNCYG
                     EFLDTKEPTDVGADVMAGSLIKNPGGGLALTGGYIAGRKDLIELISYRMTSPGIGKEC
                     GLTFGTTRNVLQGFFLAPYIVSQAVMGAIFCSRAFEKLGYDVLPKYDDLRSDIIQCIR
                     LNNADEVISFCEGIQEAAPVDSYVKPVPWDMPGYESEVIMAAGAFIQGSSIELSADAP
                     IRPPYNVYFQGGLTFDHSKMGTLKAIEFIKKLKK"
     gene            complement(81602..81862)
                     /gene="hfq"
                     /locus_tag="JAM15_01480"
     CDS             complement(81602..81862)
                     /gene="hfq"
                     /locus_tag="JAM15_01480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HAT6796944.1"
                     /translation="MKNTVLNLQDLFLNNARKERIPVTIYLVNGVQVKGLVKGFDSYI
                     ILIEGDNRQQNMIYKHAVSTIQPGKYINLTNQNQNNNNNNNR"
     gene            complement(81976..82911)
                     /gene="miaA"
                     /locus_tag="JAM15_01485"
     CDS             complement(81976..82911)
                     /gene="miaA"
                     /locus_tag="JAM15_01485"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HAT6796945.1"
                     /translation="MKKIPLIILTGPTAVGKTDLSIKLAKDMNAEIISADSMQIYEYM
                     DIGSAKVTEEEMQGVKHYLIDEVKPDYPFSVSEFQQRAKKYIHEINEKGKCVLVTGGT
                     GLYLNSLIYNMDFAQSDANNELREELQKQLAEKGIDYMHNKLKELDEESANRIHKNNT
                     KRIIRALEVCLSGKKMNDFSSDLKFNEEYQPIIIVLNRDREHLYQRINMRVDIMIKNG
                     LVEEVKKLLSMGFKKDMISMQGIGYKEILKYLDGEYTYEEAIEIIKRDSRRYAKRQIT
                     WFKRYKTAKWFDLDQYENIDELKNEIILYIKDSIK"
     gene            complement(82949..84916)
                     /gene="mutL"
                     /locus_tag="JAM15_01490"
     CDS             complement(82949..84916)
                     /gene="mutL"
                     /locus_tag="JAM15_01490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HAT6796946.1"
                     /translation="MKNIINILDDLTINKIAAGEVVERPSSVVKELIENSIDAGANKI
                     SIDIIDGGKSLIKITDNGIGIPSSEVEKSFLRHATSKIKKIDDLYDLYSLGFRGEALA
                     SISAVSKLEMTTKTKDEIIGTKIYVEGGKIISKEPIGSTNGTTIIIKDIFFNTPARQK
                     FLKSTHAETINISDLINKLAIGNPNIQFKYTNNNKQMLNTPGDGKLVNTIRSIYGKEI
                     TENIIDVEFKCNHFKMNGYIGNNNIYRSNKNLQHIYINKRFVKSKIIIDAITESYKSI
                     IPIGKHAVCFLNIEVDPSCIDVNIHPNKLEIKFEKEQEVYIELRDFLKVKLIHSNLIG
                     KYATYSDKKTQPRIAINSREKSTDYKLRNNDLLESTPKNSNITKDKDEVIEVVTLSSE
                     KPINEFQSVSEVLNASVEDDVKNINYLSEDSANDNIQEEFQVDGIKNEGNYYLGDSIK
                     DSEEEYLCSSKRKFSLYGYSVIGVVFNTYIILSKDDSMYLLDQHAAHERILYERYMEK
                     FYRQDINMQILLDPVVIEVSNVDMLQIENNLELFMKFGFELEIFGNNHIMVRCVPTIF
                     GVPETEKFILQIIDNIEEITSNYDLKGERFASMACRSAIKANDKIYDIEIKSLLEQLE
                     KCNNPFTCPHGRPIMVEISKTEIEKMFKRIM"
     gene            complement(84927..87770)
                     /gene="mutS"
                     /locus_tag="JAM15_01495"
     CDS             complement(84927..87770)
                     /gene="mutS"
                     /locus_tag="JAM15_01495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HAT6796947.1"
                     /translation="MQIDMNKLTPMMKQYLEVKNRYKDCILFFRLGDFYEMFFEDALV
                     ASKALEIALTGKACGLEERAPMCGVPFHSANSYISKLVENGYKVAIGEQMEDPSTAKG
                     IVRREVIRVITPGTVLDGNLLENKKNNYLLSLYKDGTNIGLTYVDISTGETNATCLNE
                     DKVIEEIAKIHPTEIIINDLDFIEKLRDIATVSNIYINESFSDNYLDINILKEYFPDV
                     YLQKLKFDDKGLIKSSLSILLNYIYNTQKQITSNINNINIYNSSEYMVLDMFTRTNLE
                     LTQTIRGNKKKGSLLHVLDKTSTAMGGRLLRKYVEEPLINKSKIENRLDVIEEIKDDF
                     ILREDLNDILKNIYDIERICGKIAFERVTPKELIHLKNSIEKLPNLKDTINLSNAKIL
                     KEYVSEMDKLDDIYNLIDEAILEEPTITIKDGNIIKSDFSDELKELREISKNGAFLVK
                     EIENREREKTGVKSLKIGFNKVFGYYIEITKANFKQAKLDETYIRKQTLSNAERYITP
                     ELKEIEEKILHAEEKIKSLEYEIFVEIRDTIYKNIDRIQKVAKTIANIDVFVSLATVA
                     HINNYVKPAINENNKLDIRNGRHPVVENIVGEENFVPNDTYLNRGENIINIITGPNMS
                     GKSTYMRQTAIIALMAHIGSFVPAESADIPILDRIFTRVGASDDLSQGQSTFMVEMNE
                     VSLILKNATERSLVILDEIGRGTSTYDGISLAWSIVEYIQKNIRCKTLFATHYHELTD
                     LEEEFKEVKNYSIAVKEDGEGIIFLRKIIPQGADKSYGIYVAKLAKLPDEVIERAKYI
                     LKDLEKNHVYNSVAINGDKENNNIINSNLDEELVKVNQSNFKNKYESLKIEHELIVKD
                     YKHIKKDYDKLNSKFKALNDEVALMKQNDDKEKINQEDSVKEVALTQISFDSVNRDIL
                     SEEILNLDILNMTPLDAINSLYNLQRKAKEIKS"
     gene            complement(87933..88655)
                     /locus_tag="JAM15_01500"
     CDS             complement(87933..88655)
                     /locus_tag="JAM15_01500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008677513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6796948.1"
                     /translation="MNFYHNKKVKVSIENVSKTYKDIEVLKDISIDVYEGEFVSILGP
                     SGCGKSTIFNIITKLTDYDSGKVNINGKYSYMYQKDLLLPYKTIIDNVSLPLILKKEK
                     KSKARSMVKPYFEVFGLSGYEDKYPSELSGGMRQRANFLRTFINSNDIMLLDEPFGAL
                     DSLTKTSMQKWLLDVKKKVNSTILLITHDIDEAIMLSNRIYVISKKPSIVKKEFVIDS
                     RKLNEDNLENIIKLKKEIISLL"
     gene            complement(88636..89649)
                     /locus_tag="JAM15_01505"
     CDS             complement(88636..89649)
                     /locus_tag="JAM15_01505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016207057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAT6796949.1"
                     /translation="MNFKKLGILGLVSVFTLATITGCSSNNNKDKNNDKDTSSKKVTM
                     VLDWTPNTNHTGLFVALDKGYYKEEGLDVEIVQPPESGAETLVATGKADFGISYQEQV
                     TYAKTSEDPLPIKAVATVIQHNTSGFASPKEKNITTAKDFEGKTYGGWGSPSEEAVFK
                     AVMKKNGADFNKLKIVNTGQDDFFAAMKTVDFAWIFEGWDAVKADLIGYDLNFIPVKD
                     LDERLDYYTPLIISNETVLKDNPELAKKFLKATTKGYEYAIKNPEESAKILVKHAPEV
                     DEKLALKSQEYLASKYKDDAPRWGEMKDSVWNNYTSFLKEYKLIDKDMKASDAYTNEF
                     LPQ"
     gene            complement(89671..90441)
                     /locus_tag="JAM15_01510"
     CDS             complement(89671..90441)
                     /locus_tag="JAM15_01510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6796950.1"
                     /translation="MKNLEIIDKVKDSIYPIATFLFILILWQSMVGVLEVPQYILPTP
                     VDIINVFFKDYQNLSMHAVVTIGEAILGFIVAIIISLVIGILMDFVSIIKKCLYPIML
                     VTQMIPTIIIAPLFMIWFGFGTMPKVLMVMLTCFFPILISFVDGIENIDKDYLNLFKT
                     MDSNKVNTFIHLKFPMSMDKFFSGLKISATYAVMAATVAEWLGGTKGLGVYMLRSKSA
                     YALDKVFASTILVVIFSLMFVGIVQAVKKVVIRHRLID"
     gene            complement(90416..90706)
                     /locus_tag="JAM15_01515"
     CDS             complement(90416..90706)
                     /locus_tag="JAM15_01515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002844722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HAT6796951.1"
                     /translation="MVIADIAVMPLRPYKGEEEMYKVVDACIAEIEKSGLKCEIGAMS
                     TTVEGDFDEVFELLKKVHKIPFNLGCERVITVARVDEKAGGLTIDEKLRNHR"
     regulatory      complement(90837..90936)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     regulatory      91554..91643
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(91987..92343)
                     /locus_tag="JAM15_01520"
     CDS             complement(91987..92343)
                     /locus_tag="JAM15_01520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6796952.1"
                     /translation="MDIDNNFEEFPNIEERQKDFNCSIGFTMTVIGSKWRAIILWHIL
                     KQEPIRYSQLKKEVVHISHKILSQELKYLERDGLIKRISYPTIPPKVEYLSTKRGKSL
                     ESILLELCNWGKQYMR"
BASE COUNT        33213 a        13372 c        12360 g        33540 t
ORIGIN      
        1 aaaaatatat agaaaatcct tataaaaatt taaattgtaa tgaatagtaa gtaattaaaa
       61 agaattttta ttgattttta aaaatttagt tagaaactat atcattatgg taaaaaatgt
      121 attataatgt ttagaaatat tataataagg agcgattaaa catgaatcta tcgaagaaaa
      181 tagaagataa aagaaaagct aaacagagag ctgaaaaagt taagaaagct aaaattgcta
      241 cagctggtgt ggtattagga gctgttactg gtgcagtgag tggagtactt ttggctccta
      301 aatctggaaa agaaacaaga gaggatataa aagatgcttc acaacaaatt gctgaaaaga
      361 taaatatgaa aactgtagat gtaaaaggca aagtatctga gaagctagag gataaaaaag
      421 gaaactttat agaatcaaag aaaaaaataa aaaaatatat agataacaaa aagagtgttg
      481 aaaattctag tgaggaagat aaaataatag atatagttga accagttagt gttactgagg
      541 aataatatgg acaatacaat aacgattaac ataagtataa tatatgtatt attagctata
      601 cttgcttgta ttgctttagt ttatttaatt attgtacttg ttaaactaca taagatttta
      661 aataatgttg gaactatgtt aaatgaaaat actcaaaata taaatacaac tttaaataat
      721 cttcctaatg ttgtagaaac ttttggagaa gtaggagaaa atatgaaaga tgtaacagaa
      781 gtagttactg aagttacagc agattttctt gttactaaag acagtgtcaa atcaaatatg
      841 gatgttatag tcgatatatt gactataatt aaaaatattt ttctatataa aaagtaataa
      901 atttaatata aaataagata taatttaaac gaccttaaaa taacatttat aaggtcgttt
      961 tttattagct tgatttgaca ctatgtgttt ttaataattg gtaatattcc tctttatcat
     1021 ttgaacatat atatctatgc ttgttgtttc aattacatcc ataagaacat ctttacattc
     1081 aagctcaaaa tcttccattc cttctaaata ttcatcatct tcatcaaaaa agatataaga
     1141 attatatagc cattcttcaa atttttcttc aagtatatcc caatacgaac tccaaaataa
     1201 tccacaacct gatatataag atgctctact ttgatttata taaacctcct ttagaagctt
     1261 ttgtaatcta ctgctataaa gaaaatctgc tcttccactg cttgatatta attcatttaa
     1321 atcttctatt gacattaatt caactttacc acttttatca taaggagtat aattttcatc
     1381 aacccattta tgtggtttgt tttctctgca tactgttgct atcaactcta caacttttgt
     1441 tcttatcatt tttttatcct aacttattta ttttttataa aataatcatg attttataat
     1501 ttatctattt cttgtaatgc taatttaaca gtttcatatc tatcagcacc atttattact
     1561 acatcacctt ttacaagttt attagcttct ccacctacaa cataaacctt tttacctaaa
     1621 ccttgcttat aactagacgc ctcaattatt aaagaatctt tcaattgcca atgtaaaatc
     1681 tgagcagcca ctttatcagc atcacctgta taaacgatta cattttcata cactttattt
     1741 tcccctccct cttgagaatt tgatatagat ttgtttagta taccttctgc tatcaattta
     1801 gcaactttat ctttattatt aacataataa tctgtatctg ctttactatc tacaaaacat
     1861 acttctatta atattgctgg tgcaatagta tgattaagcc aataaagacc tctaacatca
     1921 gactttgcgc ccctatcttt gaatactgta gctaacctag tattcactct ttctgcatag
     1981 gttttgccat tattagtctt atatattgtt tctgtcccta ctggagttga agttgtggca
     2041 tttgaattaa aatgaatctg aacagccaaa tcagtttcct gtttatttgc tatagcacat
     2101 tggtctgcta aatgattact tgattcatca actcttcctg tataaacagt agctccacct
     2161 gttttaagcc atttaacaat taagtcattc agtattcttg tttctttgct ttcgtttata
     2221 tacccaacag ctcctgtacc ttttccaatt aaagtgtgcc ctggtattat tactactttc
     2281 aaactaacat ctcctttaca attaaattta acttctattt aatatatgca taacctagaa
     2341 ttttgtttct ttttatatct tatactttta ttataaccca ttttgtaaaa atatagaata
     2401 ttaagtaaat aatgttaaaa ttataatttt gtatataaga cattacttga ttgcaataat
     2461 tttatagcat attcatctat tctatatcca gttctataat atatatgttt aattccagct
     2521 tgaattatag ccttagtaca atttaagcaa ggaaagtgag ttacataaat agagcaatct
     2581 ttaactgaaa taccttcttt tgcacaataa taaagggcat tttgttcagc gtgaatggtt
     2641 ctaatacaat gtccatctct catttcatga ccaacttcac tacaatgctt atctccagaa
     2701 atactaccat tatatccagt agacactatt ctgttttctg aattgacaat tatagctcct
     2761 acataagctc tatcacaagt tcctctttca gctactgttt cgcacagtct cataaaatat
     2821 tcttgccatg agcatctatt ttcaagtttt ttattcaaat catatacctc caaaatttat
     2881 atctaatata taagatttat accttaaaaa taatattaaa aacaaattta tacgataaat
     2941 aaaatttatt aatactgttt ttagtctaaa ttatttcatt ttaaattaaa gttacaagga
     3001 atctaaaatt atatatatct ttcttcgtaa tatgaatgtt acaatataaa aaactgtctc
     3061 aataaaatag agacagtttt acagtcaaag tttataatac aagttcatat ttttctttaa
     3121 attcttttac agcttcgggc catgcctttt gttctgtaat acctttttct ttagctattt
     3181 taattgcaat ctctcttatc attgcagcgc cttctaatat tcccattttt aatctccctt
     3241 caaatatctt tttgtataga atataaatag tgctaagatt tattacatgc tgcatataca
     3301 atatctatac aacacataac ttgtaaattc cttttatttt catacgtctt taaccgacat
     3361 ataattatat tcaataagtt ttaaaattat gaactcaatt ataattattt ttattttttt
     3421 agaatctaaa cactaaaaat tgtaggtaaa tttgtcttat gcctttataa atatttctac
     3481 agttttaatt actggacata tctattttta ttataaaaag cgattaaaaa tcgagaatat
     3541 ccgcataaaa actatatata agcaaaacgg ttaaaggaaa aagaagaaat ttacttgaat
     3601 gttaaaatgc gttgcttgaa gcaatgggca gttttgccta taatatcggt aacaactgaa
     3661 agaaaggtgg ttggccctaa tgttaagcga aaacattaaa acaatcagga agtcaaaagg
     3721 actttcacaa caagaacttg ctataaaact gaatgtagtg cgacaaacaa tatctaaatg
     3781 ggaacaaggg ctgtcagttc ccgattctga tatgttgatt tccatatcag aggtgcttga
     3841 aacgcccgta agcactttac ttggagaaac tattgttgag tcggaagttg atagcttaaa
     3901 agtgatttct gaaaaattag agattataaa cttgcaactt gcacaaagaa aaaacatgag
     3961 aagaaaaatg tttcattggt tatttatttt attatgtgca gtcatattaa tagtttttgt
     4021 ggtcttaggg ggactaaata gtccttactt ggattggaat tataccgacc ctgaaaccgc
     4081 tgtttttgga gtagcttttc atgcttttga gtggatattt gtcagattag taccgattgt
     4141 ccttatagga gcaattattg gaatcttttt gacacgtaag aaaatatgaa gtaactctgc
     4201 tttttataat atagcaagcg ttccttaaaa gtgtcattct acatggcaat cgaggacaac
     4261 tatgtaagga agaacctttt tgatttccaa ctaagcgaag ttattgagga cgccagtagg
     4321 cccaaaaccg cattaagtaa agtacaggaa gcaagactgc tggacttata ctctcatgcg
     4381 tcagatgcag gaaatgcgag gtctggtagc atgatttaca acgatttgta caacgactac
     4441 gagtagaaat atatggagat aagtattatc tacgaaatca gaaaagaaat gacttgataa
     4501 tttactcatg ttataattat tgatgtgaaa ttaataaatc gaaattcctt ttttagattt
     4561 aacaatactg agtaaggaaa aagtgaatga cttttgcaag gaggtgttaa tatcaggcaa
     4621 ataaagtctt ttgtttttcc agttatatcc ttaatattct tagatcaaat tagcaaagtt
     4681 cttataggat tattcttaat ggactttgaa attgatataa ttgggaaatt tttaagattc
     4741 aatcctgttc aaaatacaaa tctctcttat gggggaaact ttattggtat tctatctaat
     4801 ttatgggtat tggtattgtt taacatttta gttatattag ttattatatc tggatatgct
     4861 ttttataaat caaaaaatga acaaacaagc tattcagtaa aagtaattat gtcttgtgga
     4921 cttgctggta caatatgtag cttgatagat aaattatttt ggggaggaag tttagatttt
     4981 ttgcagatac caagcttttt tattttcgac ttaaaagact gctaccttac tgttgcagaa
     5041 ataatatttg ttgtcatagg aattttgcat aatagagaaa tatcaatgaa agaatacata
     5101 tatttttgct atcgtcagtt taaaagataa atttaagttt caaggtaaac ttatttaatc
     5161 acatcaaata gttggcttac ttaagctttt gggctaaact gtgagcactc attaagtctc
     5221 tgctatctaa caaacggagc acaaaaatga aaattaaata ttaaatataa agcacagtta
     5281 attttgatta aaaagttgac tgtcttttct tttttataaa tttaagcatg ggtaataaag
     5341 aaatgactgc atttaagcat tatgtatata attggaggca ataaaaagcc agcaaagccc
     5401 ataaaataga gctgtgctag caacatgatg agttataaga agataatcaa aagcttacgc
     5461 tttattttaa tttaaaaaaa tgattactgt aaagaaatca ttttttatta taatcactga
     5521 tacatcaaat attctaaata aaatttttat ttatctggaa ttgtatattt tttctataat
     5581 attaactaca gcgtacattg cccaagcaca aatagccaat acaaatactc ccatcattac
     5641 taaatctaat ttaaatactt gagaaccata tactatcaag tagcctattc catatcttga
     5701 aactaaaaat tctccaacta ttacacctac ccatgccata ccaatattaa ttttagttaa
     5761 atttattaaa tttcctgtgt ttgcaggtaa tatgagttta aataatattt gagatttagt
     5821 agctccaaag ctttttaaca tcttaatttt ttcttcatct atattcataa aataattata
     5881 agctgaaagt atagtaacaa caacagaaat cgttacagct gttacgacga ttccttctat
     5941 tccagcacct acccaaacta taattatagg agctaaagca gtcttaggaa gagcatttaa
     6001 aactaccaaa aatgggtcta atatttttga taatttttct gaccaccaaa gagcaattgc
     6061 taccaaaata cctaatacag tacctataac aagaccaaga acagtttcat atacagatat
     6121 tccaatatgt ttaaataatt gaccactaaa tgcatattga ataaataaat tgtaaatatc
     6181 acttggtttg ctaaatagaa atgtatttat aacatttaag tcagctaaaa gttcccagat
     6241 tacaataaaa ccaattaaaa ttaatagctg gtagaataat acatttcttt tttctctttt
     6301 tacaccttta acatagttta tatatccttc agatctttta ttaagcctca tgtgtatcta
     6361 gctccttcca taatatgtcg aaatactttt gaaaatcagg aactttacgt gttttgagag
     6421 gcgtttttgt tccatccatg ttaagttcaa tatcgtaaat attttttatg gtagctggtc
     6481 ttttagatag tattgcaacc ttatctgata tgcttattgc ttctgctata gctaaaaaag
     6541 tgcaactaat tgcttaaaga aacagaatta tccacttcag cacccatata aacaatatta
     6601 agatttccta aactgctatc ccaaatgata ctattaataa tagtagataa taacaatctc
     6661 ttatcatcta aactggcatt atcaacttca tcattaaatc tcttcaaatt actaacaata
     6721 atatcaatat taatactgtc actactaata ttgatgttac tagattccaa agtattaatc
     6781 ttatccttta aaatactaat ctcattattt aggctctcaa tctggaaaac tatataatca
     6841 gaagcagtac taccagtatt ttttgcaagc tctataacta aatttttaat aagtctttcc
     6901 ttatctaaaa tttgattttt aagtaaatta gtctcagatt taaaaatatt aaaaacatta
     6961 tcagtcttaa tgttattact attgaatgca cttataatag actcttcttt acaattctta
     7021 attttatcta taactaaact ttcaactaat ggaccattaa gatttttaca gttgcaacta
     7081 tcagacccaa gtgttttttt agtaccacaa atataataat actttaaatc cttgtcagtt
     7141 tttttgcctt tataggtaat tctcatatta gaaccacatt taccacattt tataagacca
     7201 gataaaagag cagtttttcc agttgatatc cttggagttt tatcacgatt tttatctaat
     7261 tgattttgta cttcaagcca tatttcaggt tctataactc catggtgttt tgcaattgct
     7321 gctattgagt tagatgtatt tttagcatag gtaaggattc cacattttct atctggagta
     7381 cctacaacat ccataccact atttttaagg taatctaaaa tttcatcatt agcttttaca
     7441 tatgctggat ttctaagtat tctagataaa gaactagggt caaatttacc accacgagga
     7501 ccccttattc cattattata gacatattta tataacttag ataaggacct aagttctaaa
     7561 tatttattgt atattagctt tacaatctcc atttgttcat catttacttg aagcttatac
     7621 atacttcttt cttttagatt ttcatctaag aatgtgattt tttcactgtt gaatccatga
     7681 ggtgtattgc ctccaagcca tctaccacta cgggctaatt catacatatt gtcttttata
     7741 cgttctgcta ttgtttctct ttctaattga gcaaatacac ttgatataaa catcatagct
     7801 cttcccattg gagttgaagt atcaaattgt tctttgatag atataaatga tatgcttagt
     7861 tcatttaatt tttctattaa agtagagaag tcagatacat ttctcgatat cctatctaat
     7921 ctataacaaa ctaggtaact aaatttctta tctttagcat cctgcatcat tttcttaaat
     7981 tgtggtctat ctatattgct accactaaat ccctcatctt catatatcaa aaaatctttt
     8041 acaccaatag actttgcata atcaatacat aattgtattt gattttctat agaatcacct
     8101 tttccagtaa atcttgattt tcttgaataa attgcagctt tcaaaattaa aacctcctat
     8161 aaattaggat atatatttga aattatttat atacaacctt ttaagtaaac ttattagaat
     8221 aaatttatta attaggtaaa tttatataat tctacttttt ataatatatg actatttatt
     8281 ttatttcttt actattcaag ttctaaatca ataataaatt ttgatattta attgtatcag
     8341 gacaaatctc taatttcata tattattaat ataaaatcat aggttagtgt gaaaaagttg
     8401 aaatttaaat attttaaaag ataatttttt ggaactaata ggtataacaa aaatttatag
     8461 ggggattgca tatggaaatc aatgttatag aaattttccc taaagataaa gctaaactta
     8521 ataaaataga aatggataaa gctagttggt ttgtaaatat aataagtaaa aaatatccta
     8581 aagaagcttt aaatgaagca tttagtattt tagaaaaaga attaaatata agtaaaacta
     8641 atacataagc tttgattatt gattttatat actattggtt ttatacgcta tgacttgaca
     8701 ttatattaat caaatagtat atttttaaat atagcacaat gaagtgctaa aagagcaatg
     8761 gagctccata gataaagtct atggagcttt tttgcgtatt taacttaagg aggatagagc
     8821 tttgaataac tttgagatta aaactagaat aaaatttgga gaaggttcac taaaagtttt
     8881 gcaagaatta aaaaacaaaa atgtattaat aataacagac ccttttatgg tgaaatcaaa
     8941 aacaatagat aaaataacat ctaatttaat aaactcaaca tatcaagttt ttgaagaaat
     9001 agtaccagac ccaccaatag aagtagtagt agcaggaata gaagcattta aatctataaa
     9061 tccagacgta ataatagcat taggtggtgg ttctgcaata gatgcagcaa aatctataat
     9121 ggacttttct aaaaaaatat taaaaattaa cgaagtagag tttatagcaa taccaacaac
     9181 aagtggaaca ggttcagaag taacatcatt tgctgtaata acagatagtc aaaaaaaatg
     9241 taagtatcca ttagtgagtg atgatttact tccagatatg gcaatactag acccagagct
     9301 tgtaaaaact gtaccaaatt ttataacagc agatacaggg atggatgtat tgacacatgc
     9361 tatagaagct tacgtatcta caaattctaa tgacttttca gatgcactag ctgaaaaatc
     9421 tataaagtta gtatttaaat acttaataaa agcatataaa gatggaaatg acatagaagc
     9481 tcgagaaaaa atgcacaatg catcttgttt agcaggtatg gcatttaacc aagcatcact
     9541 tggcataaat cattctattg cacatgtatt aggtggaaaa ttccatatac cacatggaag
     9601 aacaaattct atattacttc ctcatgtaat agaatataat tcatcaatag taggatatac
     9661 taacacaact tactctgata cagctaaaaa atatgcacaa atagcagaat tagtaggact
     9721 tgggagtgct aatataagaa tatctgttag aaatttagta aatgaaataa agaaactaca
     9781 aaaagaaatg aatatgccaa ctaaattgac acaatgcaaa ttaagtttag aagatataac
     9841 taatgaagaa agagaaatag caaaacttgc tataaaagat acttgtacat taactaatcc
     9901 taaggtacca actgaagatg atataataaa catattaaat aacattaaat aactacattt
     9961 tattacatgt aaatataata ttatacaaat agggaaaatg tttttaaaaa tataaattat
    10021 atattgacaa atataaaaca taaaactata atgaaagtat cacaaaggcg tgatacttta
    10081 gtagaaagca atggagcttc ttaggaatat taatattatt cttatggagc tccttttatt
    10141 ttaagcaaat agctttttaa taaactatat tcaaagaaag cagggaataa atttgactga
    10201 agaatctaag caaagagtta ttcaagaata tgttcctgga aaacaggtta cattagcaca
    10261 tatcatagct aaccctaatg aagacatata taagaagtta ggattagtac ttgataaaag
    10321 agatgcaata ggaatactta caataacacc aagtgaagcg tcaataatag cagcagatgt
    10381 tgctacaaag gcttcaaatg tatctttagg ttttatagat agatttagtg gttcagtagt
    10441 aatatcaggt gatgtaagtt ctgtagaatc agcgttaaat gatgttttag aagtcttagg
    10501 aaatatgtta aacttctcat ctacaaaaat cacaaggaca taataataca atgaagaata
    10561 taatatttat gggaaagaca ggtagtggta aaactacctt atgtcaaaaa ctagaccagt
    10621 tagaattaaa gtataaaaaa actcaatcag tggaacttta taataatgca atagatactc
    10681 ctggtgagta tatggaaaat agaaacctat ataatgcctt aataacaaca tcagcagatg
    10741 ctaaaattat agcaatagtg tatgatgcca cacaagaaga aaattatata gcaccaggtt
    10801 ttgccagtat gttttgcaaa gacgtaatag gaattataac taaaataaat aaagctactg
    10861 aaaacgaagt caatatagct tatgaaagac tatcactagc aggagcaagt caaatcttta
    10921 aaatagacac agttgataat attggacttg aaaaattatt taaatatcta gaaaaatcta
    10981 aaaatataga tgaagtttaa ggggaaatat ttttttattc aaaaatatta ttaaagtatg
    11041 ataaaataaa aaaatgtata aactatttta agaagattta atctttaagc gaggtaggaa
    11101 catggggaaa aaaatactat tggttgatga tgaaccactg ttaaggatgg atacaaaaga
    11161 tatattagaa agtcatggct atgaaataat aggcgaagca agtgatggat ttgaagctgt
    11221 tgaaatgtgt aaaaaacaca aacctgattt agttataatg gatatagaga tgccaatact
    11281 tgatggtata aaggcaggca aaataatatg taaagaaaat ctagctggtg gagtactttt
    11341 attaacttca tttgaagata aagaatacgt agaaaaggct aaaagtatag gtgcttatgg
    11401 atatttagta aaaacagcaa gtgaaaaatc acttatccca accatagaaa tgtgtttaaa
    11461 taaggtaaat gaatttgaaa aaatgaaaaa agatttagaa aaagtaaatt ctaaattgaa
    11521 tgaaagaaaa ttagtagaaa gagcaaaagg tatacttata agagagttta agatttctga
    11581 ggatgaagca tacactagaa taagaaaatt aagtatggat aaaagaacta caatgatgga
    11641 aattgccaaa atgattataa taggatacga tgactaatac gataaaaaaa atatcaactg
    11701 cacaaacata cttaaataat aacgaaattg aaaaaattat agaagtatca aaatccttag
    11761 atttaatggc ttctttttat gaggctgatg tttttataga tgtactaagt aaatttgatg
    11821 atgaagcaat tgttgtggca catggtagac ctaaagaaaa gtcaatgtac tgtgaaaatg
    11881 ttataggtaa aaaggcttta attgaaaatg aaccaggagt tataaagtgc ttaaaaacag
    11941 gagaaagagt aagagatatt aaagctttaa cacaggaata taaactggtc aaacaaaata
    12001 ttcagccaat aacactagat gacaaagttt tagcagtact aatagttgaa aaagatataa
    12061 gtagtgaagt taagaatgag tttaatgcta gtgaagacga agaaaataaa aatttacatc
    12121 agtttataaa acttatcgga aataatgact ttttagttga taatttaaat tcagccatat
    12181 taatatttga taaaaatgga aaattaaaaa ttaaaaatcg tattgcaact gagatataca
    12241 aaaatcttgg gtttggatat gatatacaag atatgcatta caatgattta gatatagaaa
    12301 ccaacacctt tgaaaatata ttaatggatg aaaattatga tgagacaaat gaagtttcaa
    12361 taggtaatat gttttttaaa ataaagacca tatacatcaa agatgatgaa tttaaggttt
    12421 gcaaaatagt acaagatata agtgatttaa agagaaaaga agaagaatta gttttaaaaa
    12481 cagtggctat aagagaagct catcatagag taaaaaataa tcttcataca gtaatatcta
    12541 taataaaaaa acaaagtaga ttatctcaaa atgatgaagt aaagcagtgc ttagataaca
    12601 taataaacag agtatttgca atactttcaa ctcattattt actatctaaa gaagttgata
    12661 ataatatatc tatacgagaa ggtatcaatt tattagtgtc aaatattcaa ggtggttatt
    12721 tatttagtaa ggatatagat atacgtataa ctggtgaaga ttttaaaatt agtggagaaa
    12781 aagcaacagc aatacttttg gttataaatg aaatactaca aaattgttat gaccatgcat
    12841 tttcggatag agaacatggt actatacaaa tattaataaa taaagataac gactatagaa
    12901 atattgctat tatagatgat ggaattggat ttgatagtaa taatataaat aaaaatagct
    12961 tagggacata tataatagat agttatataa cacagatgtt aaaaggaaat atagagagaa
    13021 aaagtaatga gaatggtaca gaagtattaa ttactatacc tacacaaatt aatatttaaa
    13081 taataactca tctacaaagt agtagtttta attgagcaaa gaggcttaag gttattaata
    13141 gattaagtta attgaatgta tttataaaaa ttataagtat atattcaatt taacaggtat
    13201 ttattataac tttaagcctc tttgcttgtt taagacatac ttaaatttta ggaggtgaga
    13261 aaatgagaga agagttatta agtgttggta ttgacattgg aacaagtact actcagttaa
    13321 ttttttctaa attaatagta gaaaatactg aatcaaattt ttcggtacct agaataagta
    13381 tagtagacaa agaaattatt tataaaagca aagtttattt cacccctctt atttcaaata
    13441 atgaaataaa tggtcaacaa ataaaagata tagttgaaaa tgaatataaa aaagcaaata
    13501 tatctaaaga ggatatacat acaggagcag taataataac tggtgaaaca gctagaaaag
    13561 aaaatgcaaa tgatgtactt catactttga gtggatttgc tggggacttc gttgttgcaa
    13621 cagcaggacc tgatttagaa agtataatat caggaaaagg agctggagct catatttatt
    13681 caaaagaaca ttcaactaca attgtaaata tagacatagg tgggggaact agtaatatag
    13741 cctcatttaa aaggggagaa gtaaccgata ctgggtgttt ggatataggt ggaaggcttg
    13801 taaagataga taaaataagt aaaaaaataa cttatatatc acctaaaata gataaaatca
    13861 taaaagataa taatttaaat cttcaagtag gcacaatggc tactgtagaa aatacaaagc
    13921 caatagtgga tataatggtt gacttattaa tggaaagcat aggattaaag aaacagacac
    13981 ctttgtttga ttttataata accaataaat caataagtat agatgaaaat attaaaaatg
    14041 tttcattctc tggtggagta gctgattata tttactatga tggagaaata aaagattatt
    14101 ttgaatatgg tgacttggga attttacttg ggcaagcaat aaaaaattgt gaatacctta
    14161 aaaaagtaaa tgtagttaaa tctatggaaa caataagagc cacagtggtt ggagcaggtt
    14221 ctcatactac tgaagtaagt ggaagtacaa taacttacac tagcgaaaag tttccactta
    14281 agaacttgcc agttttaaaa ttatcagttg atgaagaaac aggtacttca aaacaaatca
    14341 gtgaagctat aaaaaataaa cttaattggt ttaaactaga aaatgatttg cagaaagttg
    14401 ctatagccat gataggaaag aaaaatccaa cctttttaga tatacaagag tatgctaaag
    14461 ggtttgtaga tggaatgcaa caaatcatag aaaatgattt accttttata gtaattgttg
    14521 aaaatgatat ggcaaaagtg ttaggtcaag caatatatgc attattaaat tatgaaaaag
    14581 aaattgtttg tatagacagt gtcaaggttg aaaatggaga ctatatcgac attggaaaac
    14641 ctatagttga aggtaaagtt ttacctgtgg taataaaaac attagttttt aattaataga
    14701 aggaggtaag taaatgattt taaatacaaa attatttgga cgtacttatc agtttaaagg
    14761 cttatatgat gtaatggcta aagctaatga agaaaaatca ggagataaat tagcaggtct
    14821 tgcagcagaa tcagctgaag aaagaatagc agcaaaagtt gttttatcac acataaaatt
    14881 ggaggatata agaaataatc ctgcagtggc atatgaagaa gatgaagtaa caagaataat
    14941 acaagatgct gtaaatgaaa aagtttatga agaaataaaa aattggacag tctctgaact
    15001 tagagaatgg ctattggatt caaatactac aagtcttgat ataaaaagaa tatcaagagg
    15061 attaacttct gaaatgatag cagcagttgc aaaattaatg tcaaatatgg acttagttta
    15121 tgcagctaaa aagataaagg ttactgctca ctgtaataca actataggag aacaaggaac
    15181 attatcagca agacttcaac ctaatcatcc aacagacgac ccagatggaa tacttgcatc
    15241 acttcttgaa ggtttaactt ttggtatagg agatgcagta cttggattaa atccagttga
    15301 tgactctgtt gagagtgtta ctaaagtatt aaaaagattt gaagaagtaa aacaaaaata
    15361 tcaaatacca actcaaacat gtgtattggc acacgttact acacaaatgg aagcaataag
    15421 aaatggtgct cctgcagatt taatattcca atctatagca ggttctgaaa aaggaaatga
    15481 agcatttgga tttaatggcg acactataga agaagctaga cagttagctt taaaacacgg
    15541 tacagctaca ggacctaacg ttatgtattt tgaaactgga caaggttcag aattatcttc
    15601 agaagcacat catggaatag accaagttac tatggaggct agatgctatg gatttgctaa
    15661 aaagtatgaa ccattcttag taaatacagt tgttgggttt ataggacctg agtacttata
    15721 tgatgctaga gaagttgtaa gagcaggact tgaagaccac tttatgggta aactacatgg
    15781 cttaccaatg ggtgttgatg tttgttacac taaccatatg aaggctgacc aaaatgatat
    15841 ggaaaactta gccatactat taacaacagc aggatgtacg tattttatgg gaatacctca
    15901 tggagatgat gttatgctta actatcaaac aacaggatac catgaaacag catcacttag
    15961 agaaatgttt ggactaacag caataaaaga atttgatgct tggatggaaa agatgggatt
    16021 ctctaaagat ggtaagttaa cagagttggc gggagacgca tctgtattat taggatagga
    16081 ggtatttaat atgaatgaga aggatttaaa agcattggta gaacaattag ttggacaaat
    16141 ggttggagaa ttagatacta atgttgtgtc tgagactgtt gaaaaggcaa ctgaagttgt
    16201 agtagacaac aatgcttgta tagatgatat aacagaagtt gatataagaa agcaattact
    16261 agtaaaaaat cctaaggatg cagaagctta tttagatatg aaagcaaaaa cacctgcaag
    16321 attaggtata ggaagagctg gtactagata taaaacagaa acagttttaa gatttagagc
    16381 agaccatgct gctgcacaag atgctgtatt ctcttatgta gatgaagaat ttataaaaga
    16441 aaataatatg tttgcagtgg aaactttatg taaagataaa gatgaatact taacaagacc
    16501 agatttggga agaaaatttt ctccagaaac tataaataat ataaaatcta aatttggtac
    16561 aaatcaaaag gttttaatat tagttggaga tgggcttagc tcagctgcaa tagaggcaaa
    16621 tttaaaagac tgtgtgccag ctataaaaca gggtctaaaa atgtatggta tagattcaag
    16681 tgaaatttta tttgttaaac attgtagagt tggtgctatg gaccacttag gtgaagaatt
    16741 aggttgtgaa gttatatgta tgttggttgg agaaagacca ggattagtta ctgctgaatc
    16801 aatgtcagca tatatagctt ataagccata tataggaatg gcagaagcaa aaagaacagt
    16861 tatatcaaat attcacaaag gtggaacaac tgcagttgaa gcaggtgctc atatagctga
    16921 acttataaaa actatgttag ataaaaaagc ttcaggaata gaccttaaat aaagtcgagg
    16981 gagtgtagaa tatgaaaaat gatgtaattc gtcctaatat actaggaatt aaaataattt
    17041 cgaatataag tccagaaatg gcacaaaaac tagaattaaa atcacatcac aaaagtttag
    17101 gtttaataac tgcagactgt gatgatgtta cgtatacagc tcttgacgaa gcaactaaag
    17161 cttcagaggt tgatgttgta tatgcaaaat caatgtatgc aggtgctgca aatgcttcaa
    17221 caaaacttgc tggtgaagta ttaggaataa tagcaggccc aagcccagca gaagtaagaa
    17281 gtggtctaaa tgcagtagtt gattttctag agtatggagc aacttttata agtgcaaatg
    17341 atgatgattc aatagcatac tatgctcact gcgtatcaag aacaggtaca tacctttcag
    17401 agatagcagg aataagagaa ggtgaagcat tagcttattt agtagcacca ccacttgaag
    17461 caatgtatgc actagatgca gcaatgaaag ctgcagatgt taagatgtgt gaattatttg
    17521 cacctccaac tgaaacaaac tttggtggag cattacttac aggttctcaa tcggcttgta
    17581 aagcagcatg tgatgcattt gcagaagcag taaaatcagt tgcagacaat ccaacaggat
    17641 tttaaggata gttagatgga tgctataggc ttaatagaag taataggata tgttgctgca
    17701 atagaagctt ctgatgcttg tttaaaatct gcaaatgtta atattgtaag aattgataag
    17761 gttggggcag gtattgttac tttaacaata tgtggagatg tcggtgctgt aaaagctgct
    17821 ttagaagcag gtgaaatagc agcttccaga gttggtacat taagaacatc acatattata
    17881 ccgagaatcc ataatgaagt aacaaatgct ttattcaaaa ctaaagaacc taaagtctgt
    17941 gaagtttcag aagataaaga aaaaaacttt gagattacat tggaaataac tgataatgta
    18001 tcgaaaaatt tatcagaaaa agaaaatgta attttagatg tcaatgaaaa cagtggatat
    18061 actgaaaatt tatatagtga tatagataaa acaaacaaaa aaattgaaac agttgatgat
    18121 agtttaacag aagctaatga ggaaaaaata gaaaatacta atgataaaga agtattggaa
    18181 caagttaaaa tagaaaattc cgattttgat agagatgacc tatcaaagaa cagtgtaaaa
    18241 aaacttaaag ctatggctaa gaaattagat tcttcaataa cttataaaga tttaaatgtt
    18301 cttaaaaaag aagaattaat aaacttagtt aaaaagctta gcagaaggga tagatagtta
    18361 tgacactttt agataaagat ttagtatcta tacaagaagt cagaactctt gtaagaagat
    18421 ctaaagtggc tcaagagaaa ctttctaaaa tgagtcaaga gcaaatagat aaaatagtaa
    18481 aagctgttgt agatgcagca tttaataatg ctactaaatt agctaaaatg gcaaatgaag
    18541 aaactggatt tggaaaatgg gaagataaag taattaaaaa tacttttgca tctatgggag
    18601 tttatgaaac tttaaagaac acaaaaacta ttggaataat tggtgaagat aaagaagcca
    18661 atacgataga tatagctaca ccagttggag ttgtggcagg tcttatacct tcaacaaacc
    18721 caacatcaac agtaatatac aaaactataa tatctctaaa agcaggaaat actatagttt
    18781 tctctccaca tccaaatgca aaaaactgca tacttgaaac agttaatata ataagtgagg
    18841 ctgctataaa ggctggagct ccagaggatt caatattatg tataactaat ccaagtatag
    18901 ttggaaccaa tgaattgatg aaacataaag atacaaactt aatactagca actggaggag
    18961 aagcaatggt tagagctgct tactcttcag gaacaccagc tattggagtt ggaccaggaa
    19021 atggaccagc atttatagat aaatcagcaa atgttaaatt agcaatcaaa agaataatag
    19081 attctaaaac ttttgataat ggtgttatat gtgcatcaga gcaatctata gtaatagaaa
    19141 aatctatgga agaaactgtt ttaaaagagc ttaaaaatca aggtgcatat gttttaaatg
    19201 aagaggaaag tgaaagatta gcaaaattca tattaagagc taatggtact atgaatccac
    19261 aaatagttgg taaaagtgtt gaggtaatag caaatttagc agacttaaca aatgtaccta
    19321 aaaatacaaa agttctagtt gcaagagaaa ataaagttgg tcacaatgta gcctattcaa
    19381 gagaaaaact tacaccaata ctagcgtttt atgttgaaga aaatgtagaa gctattatga
    19441 acagatgtag agaaatattg ttaaatgaag gtgcaggtca tacattctca atgcatgtaa
    19501 atgatgaaga attggtaaaa agatttgccc ttaatatgcc agtatcaaga atacttgtga
    19561 atactccttc agcacttgga ggaataggtg catcaacaaa ccttgtacca gcactaacac
    19621 ttggttgtgg tgcaataggt ggaagttcaa cttcaaacaa tataggacca cttgatttaa
    19681 taaatgttaa aagagtagct tatggaatca aagaaataga agaacttgga agagataaat
    19741 ctcaagttga aaaatcaatg tttgactcaa tggataaaga agaattaata aatcttcttg
    19801 ttcaaaaact agtcaaagaa ctagcataac taaaataaac aatgaaactt atggctatcg
    19861 ctataaattt ataaaaatat aaactataaa aaactataaa attaaatttt tggaggataa
    19921 gattatggca agtgcaaacg cattaggaat gatagaaact aaaggattag taggagcaat
    19981 agaagcagca gatgcaatgg ttaaagctgc aaatgtacaa ttagtaggaa aagagcaagt
    20041 aggtggagga ttagttactg taatggtaag aggagatgtt ggagctgtta aagctgctac
    20101 agatgcagga gctgcagctg ccgagagagt tggagaacta atatcagttc atgttatacc
    20161 aagaccacac tttgaagtag atgctatatt accaaaggta tcagctgagt aatataagaa
    20221 taattttaaa atttaaattt tgattgaaaa agaggctatc tcaaaaatga gtcttactaa
    20281 taaactcaat gtattttgag gtagtctttt ttatacatct aataggagat gtgataaaat
    20341 gggtgtttta acagaaaacg aagtaaaaag aaaaattgga aaaaacaaaa ataatataac
    20401 tgaattttat atagaaaaag gtcaaataat aactccttct gcaaaatctt atttagctga
    20461 gagaagtatt gagcttaaat atgttgataa actttcagat gtaaacaata aacctaaaga
    20521 agttgtaaaa gaagtagtta aagagaaaaa atataaatat actactgtat ttggcgctaa
    20581 attggatgaa aaaccagaac atatgactca attaaatgga aatcttttag tttttaaaga
    20641 ccataaaaga ataatattga gaggaaaaat agattctctt gaatcagaaa tactaaaggt
    20701 acagatactt tgtcagaaac tagatatgcc aaagcttgtt aaggaattgc aagaagtatt
    20761 agactttgta agaaatataa tgagatgtga agttttagat gaaaagctag gggactttaa
    20821 acttttagga ttaactcctc aagaacttag agaacaatct cactatccta aaaaatactt
    20881 tggtatagga catgaattcc caagttatga aatgggagaa gtagtagtag ctataaatag
    20941 tataagaagt aatacacgag aggttgaact tgcagcctat gaagcattta agggtgagta
    21001 tggaaatgtt cacagagaag atttaataaa ggcacttaat agattatcgt cagtattttg
    21061 gataatgata tataaggtta gaactaataa gtataagtag ctggaggaca taatggagaa
    21121 tctattaaat gaaatagtgg aagaagtaat aactagagtt aaaaaagaag catttataga
    21181 agttgaagca tcaggaagac acgttcactt aagtagagaa gatgtcgata aattatttgg
    21241 agaaggatat actcttacaa aactaaaaga cctatctcaa ccaggtcaat atgcatgtaa
    21301 ggaaagagtt acaataactg gtcctaaagg aagtataaaa aatgtagttg tacttggacc
    21361 atgtagaaat gaaactcagg tagaaatatc tttaacagat ggttcaactc ttggactaaa
    21421 agctcctata aaacaaagtg gagacttaga aggtacttta agtattaaaa tatcaacaca
    21481 atatggtgaa gttgaacttg ataaggggtt aatggttgct aaaagacata tacacatgac
    21541 tcctaaagat gctgaaaaat tcaatgtatg tgataaagag atagttgaag ccaaggtgat
    21601 gggtcaaaga cctttaacat ttgatgatat agtaataaga gtgagtgaca gttttaaaac
    21661 ttatatgcat atagattatg atgaagccaa tgcatgtggt tattcaaaag gaactgttgc
    21721 taaaataata aagaaagcat aaatttaacc tactatataa attacctcta gggaggattt
    21781 aatatgaatt atgataacct tgtagattta ataacggaag aaatctataa aaaaataaat
    21841 agtaatgaaa taaaaatatc taataaacct aaagctgtga ttgtatttaa acaagataac
    21901 aataaattta acttattaaa agatgaattt gaaatagtag aatttgataa aagtataagg
    21961 gaatgtgaaa tagtgatagt ttcaagactt tgtatgagag ggctatcgaa tatagcactt
    22021 ggaaattcaa caagtgatga agaaagattt atactaaaaa tgattatgaa gggcaaaaaa
    22081 gtatatgtcc tagatgaagg aattgaatac aaaaaatata aggatactgc accaaaagca
    22141 ttatataaga aatttatgtc atttgaagat gaaatatgta aatttggtgt agaaattata
    22201 aaagacttaa atgttataac taaaaataag ttaaatataa agaaagaact agaaagtact
    22261 agaggttcta aaaaagaaga tacaaaagtt ttagataaag atgttttaaa tttaaccagt
    22321 gtagaaagtg taaaaataga taatgaattt agtttagatt taaggaataa aaaacttata
    22381 tcggaagctg acttaagaaa accaactata aatggagtta aaaacatatt agttaataaa
    22441 aaaagtataa taacaccatt agctgtagat tttatgagaa tacaccatct caaactaaag
    22501 aaactgtaag gaggtaattt tatggatata ggaaaagttg taggtaatgt ttgggctaca
    22561 agaaaagatg aaaaattatg tggccaaaaa cttttagttg taaaaatttt aaaaactaaa
    22621 gacacataca aggaaggctt catggttgca gccgataatg caggagcagg aaatggagac
    22681 ttagttctta tatccaaagg ttcctcagct agagagtcga ttgaaaaatc tcatgttcca
    22741 gtagatgcaa ctatagttgg agtagtcgat tcgtttgagg tgtttgatga ataaaagtat
    22801 aggagctata gagtttaaaa gcattgctaa aggtatagaa gtatccaatg aaatgataaa
    22861 gaaatcttca gttgatgtat tgtacttaaa aagtatttgc ccaggtaaat ttctaataat
    22921 agtaggtgga gaaacttctt atataaatga atgtgtagat tatggaataa aacttggaga
    22981 aggatatatt gtagataact tcgtaataaa tgcaatttca caagaaatat tagatggatt
    23041 taaaaataag tatcaaaagc tagatagtat agtctctata ggcgttgttg aaagtagtaa
    23101 agtatgcgct ggaataaaaa tgcttgataa gactttaaaa tctggcgact tagtattagt
    23161 aaaacttcaa ttatcttttg ctataggtgg caaattagta tatgtagtag caggagattt
    23221 aagtagttta gaatatgcat taaaagaaag tgaaaatgta gtaagagaaa aagaagtaat
    23281 atataagact gtaataccat cagtagacag tcaaataata aaaagtctaa taaaataatg
    23341 gggggaatta tgagtataaa cgaaattata atctatgtaa tggtagtctt catggtactt
    23401 ggagctatag ataaatgtat aggtaacaaa tttggtcttg gagaacaatt tgaagaaggt
    23461 ataatggcaa tggggtcact tgcagttgca atggttggtg ttatatgttt agcaccagtt
    23521 cttgctgatg tattaagacc aattgtagta ccagtattta atatacttgg agctgaccca
    23581 gctatgtttg ctggaagttt attagctaat gatatgggtg gtgcgccact tgcacttgaa
    23641 cttgcgaaag accctaatgc tgggttattt ggtggattaa tagtaggggc tatgatggga
    23701 cctacaatag tatttataat accagttgcg cttggaataa ttgaaaaaga agaccaaaaa
    23761 ttcttagcaa caggaatact tgcaggtata ataacaatac ctattggagc attcgttggt
    23821 ggattagttg caggattcga ggtaatgatg gttcttagaa acttagtgcc aataataata
    23881 tttgcagtaa ttatagcact tggattatta aaattcgaaa atgctatgat aaaaggattc
    23941 acatactttg gaaaaggtgt agtaatagtt ataactttag gacttgctgc tgccatagtt
    24001 gaagctttaa caggaatagt tgtaatacct ggaatgaaac caatcagtga aggtatagaa
    24061 atagttggag atatagcaat agttttagca ggagcattcc cattagtgtt tgttataaca
    24121 aaggtattta ataaaccatt aatggcttta ggaaaagttc ttggaatgaa tgatgtatca
    24181 gcagcaggcc ttgttgcaag tttagctaac tgtataccaa tgtttggtat gatgaaagat
    24241 atggacaata gaggaaaaat aataaatgta gcattctctg tatcagcagc attcgtattt
    24301 ggagaccact taggatttac ggcaggattt aattctaata tgataacacc aatgatagtt
    24361 gctaaattag ttggtggtat aacagcagta ttgttagcta tggttatcgc aaataagaca
    24421 ctaaggaagg agaatgtata agatggatat atcaaatata gataaaaatt taattgaaac
    24481 attagtaaga caaataatag gagaaaaaat aagtggaact aaagacacag tagattttgt
    24541 tagaaataaa gacattagtg gaataacttc tataaagtta ccaactgtaa aagttagtga
    24601 atctgataga ttagatacag ggaatccaag tgatgtagtt tacacaaaag atttatttac
    24661 attagaggaa agcccaagat taggttgtgg tatgatggaa atgaaagaaa caacttttga
    24721 ttggactcta aactatgatg aaatagatta tgtaatagat ggaactttag atataataat
    24781 agatggaaga aaggtttctg cttcttcagg tgaattaata ttcataccaa aaggaagtaa
    24841 gatacaattt tctgtacctg attatgctag atttatatat gtaacatatc cggcagattg
    24901 ggcatctcaa aattaataaa aatcaagtta agttaataat aatcaaataa ataatttaaa
    24961 atacaaactc ttaaataaac acacatattt aaaaaagcta tgaattaaaa ttcatagctt
    25021 tttttataaa gaatgttata ttttagacgt attttttcta tatttactgg gagacatatt
    25081 atatttttta ttaaataatc taataaaatg ctctacattt ggataaccaa tactatttta
    25141 ctgataatct tttccttatc actaatctta cattttaaaa tattattttt actcgtaata
    25201 ttatcataag aatttgtttc ttatttaaaa ctaattagaa ttataaagtt tattgccatg
    25261 ttattaataa aataaatcca gttaaatcga gtgctagtta aagtaataag aaacttttac
    25321 aatggtttcc tttatcgatt gaaataaaag ttaatatggt ataatatcta aagagagaat
    25381 cttatcaatt agaatatgca tagaaacaag tggcttaaaa ggagacgtta tatggaagag
    25441 atagtaaaga aggaacaagc aagtatgaat gatatttttt tgtatcttaa agctaaatca
    25501 aactcattat ataaatttgt aatattatat aatgagttta tcaataaacc taaagattat
    25561 ggaactgggg aacttataaa catggttgaa gtacatatgc taacagcgat tgaagaaaat
    25621 ccaggaataa gtccaactca gttagctaaa atatggaaca gaactaaagg tgcaatatct
    25681 caaactatat ctaaattgga gaaaaagggt tatataacta aagaaaagaa agaaggaaat
    25741 gcaaaaacta tattactata tccaaccaca tcaggagtag agttaagtaa ggcacataaa
    25801 ctatatgaca ccatagatgt tacaagaaca tttgaatact taatcaagga gtgtacatta
    25861 gaggagatag atagttttta taaagtaatt gatttgttta ttaatttatt agaagaatct
    25921 ccgcaggaaa ataatgattc tgaaaaagtg tagctaagat tgaagttgaa taaagagaaa
    25981 tagatattat agaagtagta cttaagtaca cattatataa aaatataata ggtataggat
    26041 taaaaagttt agtggtttaa agtttaacca ctaaactttt ttaatgtcta taatctacta
    26101 ttatttaatt tactaaaaat aaaaaaactc attatattaa gatgaaaata gaaaaataac
    26161 tagaaaaata ctataatata tcagcttaat acagaaaaaa gttaaaaata ttgagaaaaa
    26221 taaaaatgaa aacgttttat attgacatag agaaaaagta gtgataccat ttaaatatag
    26281 tttagtagct aaactatatt taaattataa taactatttt agggggatgt tatgaattta
    26341 aaacaattaa gtgaaaaata cgaagaatat gtaattcaaa tgagaagaga atttcataag
    26401 tatccagaat tatcttttaa agaaataaga acaacccaaa gaataaggga agaattacaa
    26461 aaaataggga tcccttttgt gtctattgaa ccaaatatcg taatagctac tatacaaggc
    26521 aaaaatgaag gtaagacaat tgcaattaga ggagatatag atgcgcttcc aatgcaagaa
    26581 gattcagatg ttgaatacaa atcagaatat gatggaataa tgcattcttg tggacatgat
    26641 gctcatggag ctatgttact aggacttgca catatgctaa atgatataag aaaagattta
    26701 aaaggtagag tattattagt ttttcaagca gctgaagaag ttggtggcgg acacaaggag
    26761 ataatacagt actttaagga aaatggagga ccagatagat taatagctac tcatgtttgg
    26821 tccgatattg aagctggtaa aatttctgtt gaaccaggac ctcgtatggc tggtgggtct
    26881 ggttggagaa tagacataac aggtagagga ggtcatggtt ctagaccaga tcaaagcata
    26941 gatcctataa agccagcttg tgatatagtt ttaaaagtat cttctatacc agttaatcat
    27001 ataagtgtac tagaacaatg tgttgtacat gcatgtgcaa tacatggagg aactacaata
    27061 ggaaatgtta ttccaaacaa tgcagaggta ataggtggat atagatattt tactgaagaa
    27121 tcaggcaaaa aagtgtttga cattataaag caaatgagta atggtgttgg acaagcttat
    27181 ggagtggatg tgaaggttac tcatactgga ggcataggac ctgttatcaa tgatgaagaa
    27241 tcagttaaga tggctaaaga aatagtttct aatatagatg gattggagtt agattcttat
    27301 aagccaatat gtgcatcaga ttgttatggt gaaatattaa aagagtattc tggtttttat
    27361 tgttatctag gggtaggtaa caaagaaaaa ggaataatat atgcacaaca ccatcctaag
    27421 tacaatatag atgaagatac attaaagtta ggttgcgaat ttatggctaa atatgcagtt
    27481 gaatttttaa ataaaaataa taactaaaat aaatcgaatt ttataaatgg ggggatgaaa
    27541 atgcaaggtg cattaaagga aaataagaaa aaaagtggtg gaggattttt aggatggatt
    27601 gaaagagttg ggaataaaat gccacatcct ctagcattat ttacatatat tacatttata
    27661 gtagtagcat tatctgcaat agcaagcttt ttaggttttt cagcaacaag tcctgctaca
    27721 ggaaagttaa taaaagttat gaacttaata agtgcaaaag gtttagtact atttatgcaa
    27781 gagtttgtta agaacttcca aaacttccct gtgcttgggg tagttttagt tatggcagtt
    27841 gccacaggag tttgtgaaaa gacaggattt ttttcaactg ccataaaaat gagtttatca
    27901 aaagttaagg ggaatgcggt tgtatttata atagctttta taggagtatt tgctaatcaa
    27961 gctggtgatg ctgcttttgt attagtacca actcttgcag gagcaatatt ttatggatta
    28021 aatagaaatc cattagctgg tatattctgt ggatttgcat cagttggtgg tggatttgca
    28081 acagctgtaa ttcctggggg atgggacgtt acgctaacgc caataactgt atcagctgct
    28141 caaactattc aacctgcatt tgatatgaca ttattagcta gttattatgc actatttgta
    28201 tctgcgttta tagtagctac agtatcaaca atagtaacgg ttaaatttat agaacctaaa
    28261 ttaggtaagt atactggtaa accagaaggt atagatgata atcaaggttt tgaggtcaca
    28321 aaagaacaag caaaagcagc aaagttagca ggttttacag ttttagctta tgtagcgtta
    28381 ttaattgctt tgtgtatacc agctaatagt tttttaagaa gtccagaagg ttctttaata
    28441 tttggagcac cacttatgtc ttgcttacag ttttttatag taatactatt cttcttgcca
    28501 gggattgtgt atggaatgag ggttggtaaa atcaagactg taaaagactt aaatgatata
    28561 ttatgtcaat caatggcagc aatggcaccg tttatcgtac ttgcaatagt tataggtcaa
    28621 ttcttaacgc tattctcagt gtctaattta gcacaggtac tagctataaa aggtggagca
    28681 ttactcaact cattgccact acaaccacaa gttataatac tgttattctt agtactagta
    28741 gcgtttataa atatatttgt tataagcgga agtacaaaat ggatgatatt tggaccagta
    28801 tttgttccga tgttaatgca attaaacata catccagcat ttactcagtt tgtatataga
    28861 ttaggagatt ctgtaactaa tcatttatca ccattaaatg cattctttat aatactttta
    28921 gcaacagtcc aaaaatacga taaaaatgca ggtatgggaa ctatattctc agctatgata
    28981 ccttacacta taggttactt tgtagtactt gcagttttag tagtagtttg gatgacaata
    29041 ggtataccag taggaatagg tggacaggtt tggttataaa acatatttaa taattttggg
    29101 aggaaagaaa atggaaacaa ctgaaataag atacaatttt gatgaagtaa tagatagaag
    29161 tggaacaaac tgtcttaaat atgatcttaa gagtcaattt atgccagaat ctccagaaga
    29221 tgcactacca ctatgggtag cagacatgga ttttgcatgt gctcctgaga taattaatgc
    29281 aatgcatgaa agaatagaca gaaaaatatt tggatatagc tctcaacaaa ctgatgatta
    29341 ttatgaagct gtatgtggat ggtttaagag aagatttgat tggaaaatag aaaaagagaa
    29401 tatattcttt agcccagggg ttgtgcctgc gttaggattt ttcacacaaa tattaacaca
    29461 aaagggtgat ggtatcataa tagaaaagcc tgtatactat ccttttgaag ataaaataac
    29521 taataatgaa agaaaagtag ttaatagtcc tttaaagttt gaagatggtc attattctat
    29581 ggattatgat ggatttgaag aattagctaa agatgaaaat aataaggtgt ttatattatg
    29641 tagtcctcat aatccagttg gtagagtatg gaaaaaagaa gaacttagaa aaatagtaga
    29701 catatgtaag aaatatgatt tgtggataat atctgatgaa atacattgtg atattattcg
    29761 taaaagtgaa aagcatatac cattagaagt agcatgtcct gattataaag atagaataat
    29821 aacttgtaca gctccaagta agagttttaa cttagctggt atgcaattat caaatatagt
    29881 aatcaataat aaggaattac aagaaaaatg gatgcttgaa acagattcta aattagctat
    29941 attcctacct aatccattcg caatagttgc tactaaagtt gcttataatg attgtgaaga
    30001 ttggatgaat caagtaaatg agtatataga tggtaatatt aaatatgtag aagattttgt
    30061 taatgagtat atgcctaaag taaagataat aaaatctcaa ggaacttact taatttggtt
    30121 agactttaga gggtatggat tagatgcaaa acagcttgaa tatgtaatgc ttaacaaggc
    30181 gaaggtattg ctagatgaag gatacatatt cggagaagaa ggagcaggat ttgaaagaat
    30241 aaatgttgct tcgcctagaa caattataga agagtgtatg aatagaataa aatgtgcatt
    30301 tgaaggatta taatagtaat atctaaataa tatatttgtg tattttaaaa aaagactatg
    30361 ctaaaaaaat atttcaaagc atagtctttt aaagttttat gatgagttta aaaaatttca
    30421 aaacgttact attattgata atcttcactt atatgtttat attagaaata attccacaat
    30481 atgctcattt tctaaagttg cacttttata caccttgctt caccaatatc atgtgtaacc
    30541 aaaatagtag acttattctc attcttaata atactataaa catcatcaca aactaataat
    30601 ctagtctgat aatcaagagc tgaaaaaggt tcatctaaaa gtagaatatc tggatttaca
    30661 gaaagtgttc taataagcgc aactctttgt ctcatacctc cagataattc ttttggatac
    30721 atacttctaa aatcccataa tccataagtc tttaaaaggc tttcaactct atctaaagat
    30781 tttttatctt ttttgccttg aatttccaat ccaatagtta tattatccat tatatttctc
    30841 cattcaagca aattatcttt ttgaaacata tatccaatat ttccagtaat ctttatatca
    30901 ccactagtcg gttttaaaag attagtaaga atatttaata ttgtagattt accacttcca
    30961 gaaggaccaa gcaaagttaa tatttctcct tctttcaagt taaaattgac atcctttaat
    31021 acttcaagct cgccttcctt agtgtagaag ttcatattta tatttttaac ttctactatg
    31081 ttgtcattca ttatgccacc ccctataact tttagctcgt atatattatg ttattaacaa
    31141 tatgaactat ttgtaccatt tttcataaat ataatataaa tattttgttt atttacgtat
    31201 tttcttagta acttgtacgt ataaattata ataaataaat tataaggtag gggataaatt
    31261 tgagtaacat aataacgaat ttaatagagt cagtatttac taatccaata actatattgt
    31321 ttttacttgc aataactgtg tattctgttt ttaaaataat agaaaataac agagtatatt
    31381 catttgtaag ttcaaaatta gacgaaatca atagagatta taagacaagt gagttttata
    31441 aaaaggtaag ggatgactac tatacatata gtaaagaaaa tccttatgca gacgtaaata
    31501 taacttcatt tatagaggaa gttgtatctg atttaaagca taataatttg ccattgttag
    31561 aaaaaattag aagtataaaa aattcatctt caataagtat attacttggg gttttaggta
    31621 cgtttgttgg tctttctaca atgcttttat gtgttgatac taaagacatt ataaattcac
    31681 ttccttcaac tattagtagt atgcaaactg catttacaac tagtatattt ggagttgtat
    31741 tttctctaat tataggttac tttactaaga taaaagattg tgaacatgtt ttgatacaaa
    31801 taatgttaaa atctgaaaat ttactaacat ctgaaataac tcattttaag tcagaaagaa
    31861 tggatttaaa agtagaagag gtaaaaaata caataaaaca aataagtaag tctatagaag
    31921 ctattgaaaa atttgataaa atatctaaag atttaaatga ctttaatgat gaatttatca
    31981 gtggtataga agctttaaaa agccttttag aaggttctca aagttctatt aagacatttg
    32041 accagagcgt aagaaaatta gataaacagt ttaatatttt aaatataaaa tttgtaaagc
    32101 tttttgataa atatgataat caagataata taaataaaga gattttattt gatataaaag
    32161 aatcttcaaa aaatatatac aatgccactg aaagccaatt caaaattaga gattatataa
    32221 aaaatataaa tgcaggattt gctctatatg aaagaagtgc tcaagattta ttaactaaat
    32281 taatgaccca tgaaaataaa atctctcaaa atcaaaaaat ccttttagat gaaaagttta
    32341 ccttagatga ctcaataaaa aatctctcaa gtattattga aaacttttct aatgacctac
    32401 aaattaaact ggatatgatg tttgaaaatt ctttagatat tcaagataag ttagatgtta
    32461 tgtttaataa ctcttttatg aatgatgaag ttcctcttga tagtgaggaa ttatttaagg
    32521 atgatgttaa taatgtattt aatcctttta gtgaagaaat ttatgagata gaggataaag
    32581 aaataaaggt cataggtgag gatgagttaa atgaataata aatatagaag aactgttaac
    32641 agagaatttg aaaagagtag cttttggcca acatttacag atttattatc tactgtattg
    32701 atggttgtga ttcttatctt atttagctca gaaagtattt caggttctgt tgaacaagat
    32761 ttagctaaga atgtcaatgc ttctgttgaa gaaactttta aaaaaagcaa aatacctgtg
    32821 aaggtagata aatctaatgg gcaagtaact tttggtgaaa aaaccatgtt tgatgtagat
    32881 agtgatgttt taaaaccaga ggctaaagaa atgctaaaaa tgtttgttcc aaagtacata
    32941 gagactattt ataaagatta tggtgactat atatccaaaa tagttataga aggtcataca
    33001 gatgatgtgg gaagttatat atacaactta gatttatcgc aaagaagagc atatagcgtt
    33061 gctaaattta tagtgggaga tgaaataggt gactataaat acaaagataa agtgactaag
    33121 catattattg caataggaag gtcaaaagct gaactcatca aaaatggtga caatagcgtg
    33181 aatagagatg catctagaag agtagaacta aaatacgaaa taaatattaa tcaaaataaa
    33241 taattaaatt tttataaaaa aaaagaaggc agttggtgtg agctttaagc cttctttaag
    33301 gaaaaagttt atttattttt gttgatactt aacatattat agtttttaga agcagtttgc
    33361 aatatattaa acgtaaatgg tcgtttaaaa tgcataactg gatactactg atgtaaaata
    33421 tttcgtttta tataatataa aaattataca gtgtcaattt tctatattat tgtactataa
    33481 tctattattt aaaatattat gtaaaaaaat atcataaaaa cgcatatcat gttataatta
    33541 ctagagtatt atgaatatgg aggcgtagtt tgtgatagaa ataagtataa aaaataaaaa
    33601 aaattctaaa attaaaactt tgatactttt attgatagta tctatatcga tttatttaac
    33661 tggttgtact acatcagata atggaaataa tcaatcaaat aataatgatt ctttgtctag
    33721 tagtatatca agtgataaga atgtaaaaat tcattttatt gacactggaa atagtgatgc
    33781 aatattgatt caagatggta aaacttttac attgatagat gggggagata atgatgatga
    33841 gggattaatg gtagattacc taaacaatca aggtgtaaaa gatattaaat atcttatagc
    33901 tacccattct catgcagacc atttaggtgg acttgattct gttgtcaaaa actttaatat
    33961 agaaaatgtt tttgtatcga atggttcagc agaaacaaag agttataggg actttataaa
    34021 tgctttagca aataagggtt tatccccaag tgtaccgctt gaaaataata agttctattt
    34081 agaagattct tattttgaag ttctaaatac aaatggggga gatactacta atgaacaatc
    34141 tctagtcctt gtatatacta atgggaatga taaagtttta tttacaggtg atgctgaaga
    34201 aggtaccgaa aaagaaatac tacctaagct tgagaaagta gaccttttaa aagtagctca
    34261 tcatggttct cgtagtagtt catctcaaga gtttttagat aaagtaaatc ctgaatatgc
    34321 ggttctttta gtaggcaagg gtaattcata tggtcatcca catcaggaga caatgaataa
    34381 attgaaaaaa atgggagtaa aagtacatag aagtgatgag tgttcagata taatatttga
    34441 atcaacaggt gatggagtat ttacaagttg taaagatgga agttataata aaggtgttag
    34501 agaagatgga aactctggaa aatcaaacag taatacaagt aaaaatgatt cttttaaaaa
    34561 taaacaaaat acattcaatt cagaagaaat agtgtatttt actccaaaag gtaagagtta
    34621 tcactctata aaaaattgta gtgggctttc aagaagtaaa aaaatattat caggcacaat
    34681 tgaagaaagt aagaaaaatg acccatgtga tatatgttat ggaaaataac aaaaaaacaa
    34741 ccaatttatc tataaagctt ctgaacttta aatcatttaa aaaataaaat aaatgcataa
    34801 aaaaaataag ctataatcaa tagataatac atttcatcta tacgaatagc ttattttttt
    34861 aagtattttt taatagctat ttaataactc taaatacacc agttacaata cctacaattt
    34921 caacttctga gtcattgagc ataattggtt ccataaaatc attttctggc tgaagtctta
    34981 ttaaatttcc ttctttaaaa aacctcttaa ctgtagcaga ttcaccattt ataagtgcaa
    35041 ctactatctg agaatttaag gccgtatttt ttttgtctac tacaacgtaa tcttcatcta
    35101 aaattcctgc attaatcata ctttcgcctt ttactcttaa tacaaaattg ttactgccct
    35161 ttactaaact ggcagggaat ggaatgtatt cctctatgtt ttgttgagct aaaatgggtt
    35221 ctccagctgt tatttgacct actaaaggaa gctctattat ttcttgatta gctccagaaa
    35281 catcatttac tttactacgt tctaaaactt caatagctct tggtttagta gggtcctttc
    35341 ttatgtatcc cagtttttca agtttattta gatgagagtg cacagttgaa gtagatctta
    35401 accctacagc agtacatatt tctcttacag caggtggata accttttaat gtgatttgag
    35461 actttataaa ttccaatatc aagacttgct tttcagttag atctaaatac ataacatcac
    35521 tcatttccaa acatattttg tttttatttc catacacttt atatttttaa ttataacata
    35581 atccatttat atctgcaaac atttgttcct gatttttaat cgtcctcaat ccattcaaaa
    35641 ttcttgacta tatcacgttt tacatttttc ttatgagctg cataaagctg agtagttgtg
    35701 acattatcat ggtcaagtaa gttttgaaca tcatatatag aaaatcctgt ttggattaga
    35761 gaagttgcag ccgttgctct taatttatgg ggactatatc cattgtctct agtagtatca
    35821 agtggaatag atgtatattt ttttaccagt gttcttatag cctttgctgt aattctctta
    35881 ttttgaagag acaaaaataa agcatctttt tcttcatcat ttaatagttc atctcttgtt
    35941 ctttcgtttt gcaaataatc ttttattaca tgttcacaag tatgatttat aggcattaaa
    36001 acttctttcc cacgttttct atatatttta aattcacctc ttgaaaaatt aaaagaggag
    36061 atattgagtt ctctaagctc atttaatcta agcccgtatg taacaaataa tgctagtata
    36121 gctttgtcac gtaatttagt ttttctccaa tatacctttt ctttctctgt aagcccttca
    36181 cctgtttcta ctgattcaag catcttagca acttcatcta tctcaaggcg cttaatagca
    36241 tctggctgag gtttaggaag ttttattgga ttgaatccat cagttatatt attatctatc
    36301 tgagagtttc tgtataagaa tttaaataga gtagagatgg atgatttttt tcttgctaac
    36361 gctctattgt tattttcaaa aatcaatgtg tttttttctg tatttttgta atatctactg
    36421 caataatcac ctaagaataa atttatatct cttgatttta ttgtattaaa atcatcttct
    36481 gtaatatctt ttacacaatc tgcatttgtt aattctttag tttcaatcaa atatgaacaa
    36541 aaaaaattaa tatcttctaa ataagcaagt cgtgtagaaa ctgcaacaga accttttaaa
    36601 tatataaaat aatccttcat aaatacagga agtttatttt ccaaaagtag acatttttct
    36661 atgagttcat tttctttgat aacaatatta tcaggtttat ctgatttatt atgtactttt
    36721 ataattttct tatcattatt caaaattaaa cctcctaaaa ctaaaatata aatcttttat
    36781 attatttttt gatatttata ccaagtgagt ataaatattt aatttaatca ttttttacat
    36841 ttttaagaga ttagcagtgc tttagatgaa attatcacta actattccct aaatccacat
    36901 ttaaagacta gttgaattta agtactcttt ttttatttct caatatattt atagaaattt
    36961 tttaaaatat attgagaaat tttttatgct ctactaaaat cttttttata taatattttt
    37021 atatgtttct aacgaaacca aatattagta aaatatgtat ttatttaact aaagttttta
    37081 aatgggctga ctaagcttaa aatataggat attatgagag ttactattga aaaaataaac
    37141 cctattgcca taaagaaact tataaatatg ttatacttaa gtattaaact ggatatattc
    37201 aagttatcaa atccaaataa gtatgtaatt gaacttatta caaaaataac tataactata
    37261 aagctcagac catttaagct attttttaaa tcagcactac taagtgacat atgtgtagat
    37321 atagaataca ttaaaaacat aaatataaaa tacttcaatg aatatacact aggtgttaac
    37381 aacattattc ttataaaatt ggaaatatca cctaaaataa tgtgtataaa accatttata
    37441 tttaaattat taatcatact tacatataac tttaaatcta tattttgagt cactttcata
    37501 taactatctg gcagtaatat cttaaaaatt aaaataatca ttattgttcc acctataata
    37561 ggtgcaattc ctataaagaa atttcctata ctttgataaa gattatcttt tttatagcta
    37621 tgacttacat atcctagtat accatcattt ttactttcta ttggtctgaa aaacttaact
    37681 gaatttattt tatgcatgaa aatcaagcac attatcaaat gactcaattc atgaacaaac
    37741 gttcctatag ctccagttac aataattcca gtttttccaa aagatgaaaa gataaattta
    37801 ttatttagat tttctgtaat gctaaaaatc aatccaaata caataaatat tcctatgaaa
    37861 caaaaaatat ttattacact tatttttaaa atttcgatta tataaatcat aagttaagtc
    37921 ctcatgtaaa agtatttaac tactctactt catatccatt acagcttaaa attttacaag
    37981 cattttctat atctttttct tttactaaga tatagtctgt atcatacgta gaaattgcaa
    38041 atatgcttat tttgttgtct gctaacaaac tacttaactt agataaaatt cctacaagtg
    38101 aaaagtctaa aggacctagt atcttaagta ttctccactc cttttctgac ttaacatcag
    38161 aaggaatatt attatttaaa catacaacac ttaattcatc atcagttcta gttatagagt
    38221 aaagcttctc tgtatctatc catgttggta ttttactgtc attatttaat ctacatactg
    38281 catactcttc taccaataat tttaatttca taatgtatat ttcctccaat cttatttgtt
    38341 tacttaagat tatacattaa aagttacata aaataaaaca tataaagtaa aaaaggttca
    38401 ctatagtgtc ctatttctat agccaacctt taaaacttaa ttaaattcta ataaagagat
    38461 atattatcta ggttcaatta taagtttaat ggctgttttc ttatcacctt cgatttctat
    38521 atcagtaaat gcgggaatgc aaactaaatc cattccacta ggtgcaacaa aacctcttgc
    38581 tattgcaatt gattttatcg cttgatttag agctccagct cctatagctt gtatttctgc
    38641 aacgcctcgt tctcttagta ctccagccaa ggctccagct acagaattag gattagattt
    38701 tgatgaaact tttagtacct ccatttcaac atctccttgt taatttgtta aagtatccat
    38761 tacctaaagt actaaatcat aattgccatt tactaattac aatcatcatt taaagtatac
    38821 ttttataaaa atatacttct ataatcgttt taagaaaacc tttatttttt ttaaccattt
    38881 tattatgaaa aaactacaaa tttctttata ttctataagc attttccaat atttctaaat
    38941 tttttatatc tttgagctat aatttcctct ttatccatat ctttgtaatg atttaatctt
    39001 tctaaaatat aagcttttat ttcttttgaa acagcttcta catctttttg tgctcctcca
    39061 agaggttctt ttataatctt atctattatt tttaaatcat ataaatcatt acttgtaagc
    39121 ttcataacat cacaagcttc tttagcttta gatgaatctt taaatagaat actagaaagc
    39181 ccttctggag aaatcacaga ataaactgaa tgttctagca tacaaacatc atttcctact
    39241 ccgataccta aagctcctcc actaccacct tcaccaatta caaaagtgat tactggaaca
    39301 gaaagtttac tcatttcaag taagtttctt gcaatagctt ctccttgtcc tctttcttct
    39361 gcttctagac cacaaaaagc tcctgatgta tcaataaacg ttattatagg tctattaaat
    39421 ttttcagctt gtttcataag tcttaatgct tttctgtatc cttctggatg aggcattcca
    39481 aaatttcttt ttatattttc ttttgtatct cttccttttt ggtgtccaac tatagtaaca
    39541 ttaaactttc ctatctgacc aatccctcca accatagaag ggtcatcttt aaaaagccta
    39601 tctccatgaa gttctaaaaa attagaacaa atatgttcta tgtattccaa tgtcgtaggt
    39661 ctctttatat ctctacttag tgttaccttt tcatatgctg atagatgtga aaaagcatct
    39721 tccttaagct tttccaattt ctcattaagt gaatttattt tatcacttaa atctatatta
    39781 tttgccttag aaatagttat taattgttta atatcatttt ctaagacttt tattttttca
    39841 ctattatttt caatcaaaac agttcctcct ttatgcccta tttcttgtgc atagcaagaa
    39901 tttgatataa taattccttc atttttcttc tatctactat catgtcaata aaaccttttt
    39961 caagtaaaaa ctcagaagtt tgaaatcctt caggaagttt ttgatttatt gtttgctcta
    40021 ttactcttgg acctgcaaaa cctatcaacg tatttggctc agaaattata atatcaccaa
    40081 gcatagcaaa actagcagtt actcctccag tagtagggtc agttagaact gatatatatg
    40141 gcaatgattt ttcttcaagc ttagaaagtg cttgagaagt ctttgccatc tgcataagag
    40201 ataccatacc ttcttgcatt ctagctcctc ctgaagcaga acaaataatt ataggtaaat
    40261 tattttcagc agcatactct attgaataag ttattttttc cccaacaata gaacccatac
    40321 ttcccatcat aaaatcagga ttcattacac aaataactgt tttaattcca tttattcttc
    40381 cataacctgt gacaacagct tctgactctt ttgttttttc cttataagag tctacttttt
    40441 ctttgtattt aggaaaattt agtggatttt gaaattctac atcagaatta aactccataa
    40501 aagttccttt atcaatcaat aaatttattc tttttcttgc tcttaagcca taatgtcttg
    40561 aacattttgg acatacaaat gaattttctt ctatgtcctt tctaaataca tgactatcac
    40621 aacctttgca ataggtccaa aatttatcat ctacactatt ctttttaaag ttgtcatcta
    40681 aagaaatcgt aacatactta gattcttttg atgataaaaa tttttttatc ataatctatt
    40741 tactccttat aatgtagcaa attctttctt cataaagaca tcttctataa atttggtatg
    40801 atgagtatct tctctaaact cctcacttgt tacaagtgcc ttttgaaatt ctacatttgt
    40861 attaatacct tctacaataa tttcgtctag agctctatac attctattta tacattcttc
    40921 tctagtctca gcccaacata ttaatttacc tatcatagaa tcatataaag gtggtatagt
    40981 atatcctgca tatacaaaag tatcaaatct aacgccaaaa cctccaggta aatttaatga
    41041 ttctatctta cctggtgatg gagcaaagtt atttgatgaa tcttcagcat ttattctaca
    41101 ctcaatagca tgacctctaa aagcaatatc ttcttgttta aaaggaattt cttccccatt
    41161 agctatagat atttgaagtt ttataaggtc aagatttgtt accatctctg taactggatg
    41221 ttcaacttgt attcttgtat tcatctctat aaaataaaag tttttatctt tgtcaactat
    41281 aaactcaata gtaccagcac cgatataacc tacacctttt actatatcta ctgcgatttt
    41341 atgaagtttt tgtctttctt catctgaaag gtatggactt aaagattctt ctattacttt
    41401 ttgattcctt ctttgcatag aacaatctct atcacctaaa tgtattgcat ttgagtgttt
    41461 gtccccaaat acttgtactt ctatgtgtct aggattttct atgaattttt ccatatataa
    41521 atcgctatta gaaaatgccg ctagagcttc tgaacttgcc atatcaaaat ttgaaaaaag
    41581 ttcttcttct tttctaacga ttctcatacc ttttccaccg cctccacttg aggcttttat
    41641 cataacagga tatccaattt ctcttgcaac ttctaaagct tcttccttag ttttcaaaac
    41701 agattctgaa ccaggaacaa cagggatatt caattccatc atagtttctc ttgctctaga
    41761 tttatctccc atcaaaatca tttgttctct tgttggacct ataaaaataa tattattatc
    41821 ttcacattgc tttgcaaatt caggattctc tgataagaat ccaaagcctg gatgaatagc
    41881 atcacacttt aatttaagag caagatagat tatattttct atattattat aactcttact
    41941 tatattattt ggtcctatac aaatagattc atcagctata tatctatgaa aacaatcttt
    42001 atctatttca gaatagatag caacagtttt tatacctagt tctttacatg ttctgatgat
    42061 tctaactgct atatcgcctc tatttgcaac tagtattttt tttatcaact taaatacctc
    42121 ctactacaat ggttttatct taaataaagg ttgattatat tctactagtt cttcattact
    42181 aactaatact tcaattattt cacctttaat ttcacttgtt atctcattca taagcttcat
    42241 tgcttctaat atacataaag tgtcgccttc ttcaactaca tcgccaactt taacaaagct
    42301 atctgcatct ggacttggag aatcatagaa tgttcccatc aaaggagcta ctactactga
    42361 tagattctca ttagatgtga caggtgtatc gtttacaact ggcttttcta aagaaagatc
    42421 cactactgat tcttgttgta cacttaaaac aggtgaactt gtagattgag cttttttaga
    42481 tacttctaat cttaaatcac tactttcaag ttttacatat tctaagttag ttgagtctat
    42541 ggcctttaat aattccttaa tttcattgat gttcattttg ttaccccctt gtattattac
    42601 ctggtgctaa tattatatca caaaaaacaa atttataaaa gaaaaagtgc tgactagaga
    42661 atcaacacat caatatatct tttaatttta aattaacaac cagtaactta tatttgtttt
    42721 aattttccat tattaatata aattataagt ataaaatgaa taaaattcaa tattttttgc
    42781 aaaatacaag agaatacaaa ttaatacctc gggaattttt aagacaaata ccaatattat
    42841 gcaatttaga cttcgctttc tttcaaatta gtatcatttt ctttattttt acataggatg
    42901 tactttaatt tagctatcaa aacattgcta tataggttaa aagttattag aattgcagga
    42961 attataaagt aaactctagc acctataaaa ccaaaaacta ctgtaataag tattaatctt
    43021 ttatttaaag taaaaaaagg tatattaaaa atacttttgt cggatgtttc tggagtataa
    43081 gaatatataa ctccaaaaat caaagtaagc atacaaagtg gaagtagtgt ataacttgaa
    43141 attattccca gaaatcctat actttcaaaa tatttgctag cactatttgt ataaacaaac
    43201 atgtatccat ttaaatatgc gcatatacat gatataatgc caaaagttcc ccctaaggat
    43261 tgagtgtacc aattaaaaaa tttagattcc atatacctca cctcctaaaa ctgtatatat
    43321 aatgatatgc atttaaatag taaaatatat ctttatatgt ttctgaataa aattttgtta
    43381 atttcattaa tttatgttta agaaatttga agtatagtgt agtatatatt aatgtagatg
    43441 aagttttata gtacttattt catagtgctt aatcaagtta tcttattatg gattcaaaag
    43501 ttgtttgtag ggttttatat tttgttgagc tgaaaaattt attataaatg aagggatgtt
    43561 ttcgctttgg tagatacatt agaatttggt cttaaaattt tattttttat attatcaata
    43621 atttggatgg gtaaaataat gattttaaga actgataagc aaatagtaat caatcctttg
    43681 cttattggta tatctgcagt ccttgtgatg ttgcatacct cacagagtaa cattgaattt
    43741 tttggattag atgtccaata tataagaata gttttgtata taatatattc actgataatt
    43801 ttaataggaa tatgggctac taacagaaga aatggaattt tttagataat ctatttctat
    43861 aaaatttaaa ggttgctagt aacaaagcac taatattagc gttctgttac taacaacctt
    43921 tattttgatt atacacttaa attgaaaata gaatgattga ataagttggc atattatttt
    43981 acattgacag taattagaac ttcttgagat gtatttaaat catttttgtc gcttagtata
    44041 acttttacca ctgcttgacc tgttttatta cctttaatta tcatatcttc acatgaaagt
    44101 acactcttat cacttacaga tacaataaaa tttaaatctt ttggaaggtt atcagtaact
    44161 tcccagtatt tataataact atcaattttc ttcgtaatta tttttctcaa atcaatactt
    44221 tcaccttttg ctatatcaac gttatgatat ttagagtcca gtttatactg attatctttt
    44281 gtatcaataa aatttaaatc gcaatttaca tccacaccat tatgagaaag agaatttact
    44341 acatcgtcat caatcaaata attattggca agatttattg aatccatatc ttttagactt
    44401 aaagcttcct taggaacctc ttttatatta ttattccaaa aaataaaatt gtctacattt
    44461 tcaagatatg atattccttt taaatttgaa atgctctcac cagttgcata aaattctcca
    44521 tctaaagcct ttatattgct tatagtcatc tcatctggat ttatatatct ttttacaact
    44581 gctcttaaat ttgcatcagg aaaaatatct ttaagttgat tttcgctcaa aaccttatca
    44641 tttgaattta ttggacttaa agctgctgca gaaataataa atggtattaa attagctaaa
    44701 ttcatagtac cctcccacat aaatttttta ttataataat ttaatttcta tgagagggtt
    44761 ctgtttcctt gttatatata cctactttcg tacactttat taatataaat taaaataaat
    44821 ttctactatt aaacttataa acatattact agttacgttt tttagcttca catctaaata
    44881 ttcgcatacc ttgtgacata aatttgtctt catactctgt tgtaacatta ttttcatact
    44941 cactatttcc taaatcaaga gaaatattct ttaatagcca attatttgca gcaatttcat
    45001 ttaaactaaa ctcgaataat ttttcattat ctgttttaaa gtgaatttcg ccatcatctt
    45061 ccaaaaccct attgtacatt tctaaaaatc cagaatgagt gagtcttctt ttactccatc
    45121 tatttttagg ccatgggtca cagaaattta tataaattct cgataattct ttagcttcaa
    45181 agtaatccaa aatattgctt acatctcccc ataaaaatag tatattattc aaattagaag
    45241 catctgcttt ttcaacagct tttaaaagaa cttcttcctt aagttccatg gcaatataat
    45301 ttatgtcagg gttctgctta gctaaagttg ttataaactt accttttcca gtcccaaatt
    45361 caacatgtat tggattatca tttctaaact ttaaattcca cttgcctttt gatttgtcta
    45421 tatcgtctct taaaacatat tttgtataac ttaaaagctt ttcatctgca cctttttttc
    45481 gtcttcttct cacaataatt ctccttacat ataaaaaatt agtaaaatac atttttatta
    45541 tacattatct caccaaaaaa taaaaagaac tctcttaaaa tagaaattta tttctataaa
    45601 gagagttcta aacttactaa aaacttaatc ttagtggcac cctgaacaac cagagcatcc
    45661 tcctccacct tgatctttca tattttcagg aataactcta aatccaaatc ctgtatcttc
    45721 tattattata tctccatact gactatattc atcagagctc attacaaatt gtaattctcc
    45781 aacttcataa gttaagtcat cttctttttt ctcatctaaa gctaatccaa aagaaggacc
    45841 tccacaacca acacctgcaa agtatactct tatattatta ggtttatctt gattgtcttt
    45901 taagatactt tttaaagtat caatagctgt ttctggtaaa gtaattttca tcaaatcatt
    45961 ccctttcaaa tattttatta aaacaatatc tattatatac ccatacaagg tacataatca
    46021 attagttttt gcatatttta ctaaaacttc tacctaatat tacctaagac tttaaaatat
    46081 tttatataat attttattac cttaaataaa taccctatca taaacttagt aaacaaataa
    46141 aattattcta aaaaatataa taattttatt tgttgtttta atattataac acatttgata
    46201 atgtccaatt catatatgca aaaatttata tactttaaaa tatctaagaa attattcaat
    46261 aaaaaaatac tattttttaa aaattatcat tattgataaa gctctactat ttatattttt
    46321 tagtgtattc atgtataata agtaaaagca caacggtata tactgttgtg cttttttgta
    46381 attaataaac aatattttgg tctataacaa tgaaaaatgg ctactttcca taattgattt
    46441 catctgacat aagcaaaaag ggtgtccagc tgggtcaatc ataactctcc agtcatcagt
    46501 aaattgctcc tctgcgattg tagctccaca atgaattgca tattgaactg cttcttctaa
    46561 atcattaaca gcgaaatcca tatgagccat ttgctgttga gattcaggtt tttctggcca
    46621 cacaggcggt ttatactcag aatttcgttg aaatgttata ccaggatatg ttccctgatt
    46681 tgttcctgga gcaccaacac atgcatattc ttcattataa aatgctattt cccaattgag
    46741 taacgctgca taaaattttg ctaattcatg tgggtctttg caatccatcg taaatgagta
    46801 cattttgatt ttcagttcat catgcataat gtaattacct ccaagtataa atttcttcgt
    46861 cttttcattt ttaagctaaa ttcaaacatt aagtatgtaa tttatttcaa gtatttttct
    46921 attatgcccc aagcctttgt tttttgcaat ataaagaaaa aattatatat tttaatattt
    46981 tataattgtt gaaattgtgt aataaattca actggataca tagtgcgttt tgaaatttct
    47041 tctaaagcta aaccttgttt taaaagcctc tttatgacgc tttccatact ttctgaaatt
    47101 tctataatat ttttatcaaa atcataaaac ctaaaagttc tttgacccca tgggtattct
    47161 tttatataat gcaaaaattc aatatttcct attctattta tcttactttc ccattgtttg
    47221 atatcattaa cctcaaaata caactgaaag ttatttgatt gttgatatat tggtaaatca
    47281 tatccaatta tagctttata attactttgt aatccaaatc cattttcaaa tgatacatgt
    47341 tctcctaaat ctaatgtaat tttttgctcc ataacatctt cataaaactt ttttgattta
    47401 tttatgtctt tgacaattag caatactcct ccaaatttca tcttatcact atcctttctt
    47461 tgttataagt attataactt aaaattttgc aatttcactg taaaaatcag acatattagc
    47521 tcggtatttt tgaggagtta ttccacagac aattttaaaa tctttaataa aatgtggtat
    47581 atcatagaat cctaattcat tacatatata catcaatgaa gttttattat tgtttagaag
    47641 ttttatagat ttattaatac gtaccaaacg agaaaatgac ttcatactca accctaggta
    47701 ctgattaaag agtctgttta aatgcctaga actataaaat acttttttag aaatttcttg
    47761 tgaagatatg tttccagagt tttgaataat caactgaatt gccaaaataa actcatatga
    47821 gtattcaatt ttaatattag aaatcaataa ttcttccaac tttaaaatca atttatctat
    47881 agataaagat tcattaaata tttttttaat ttctaaatct aatgaagtat taattataga
    47941 aaatggaaca actttatcaa taagttcact ttgctgtata cctataagcg ggaaaaaacc
    48001 agcaggttga aattctataa ttagtataac atcacatcta ttagcaatat ttcctactgt
    48061 ttttggttta gtagttggac caaataatag actatgtaac cctgtggcat cataaaaaaa
    48121 caccaaagtt acacttccat gaggaataat cgtgtaatta tcagaaatta ttgtttgatt
    48181 tggaaacgat atagtaaaat tcgatatcca atttcttaat tgtatacaag gcaagagata
    48241 aacaaaattg tcttcacaaa ctataagtga cctattattt ataaaatgaa tactttcttt
    48301 ttttaacata tattatatcc tgtcctatca tgaatattta ttaaagtaag aagaatccat
    48361 attatctcta tatatcatta actgctttta ataatagaga tagaatgaat actcattaga
    48421 tatttaataa acaaataaaa ttaaaataat caataaaaaa tatagtactt ttatctgtta
    48481 ttttaatatt atagcacatt tatagtatct aacttatatc cactttacat atgtctaatt
    48541 tatataatta aaaatgctta tctcaaatac aataattagt ccttatacaa ttaaaccatc
    48601 tgaaactgta atagtacgac tactactttt ggctgcatct ggtgagtgag ttaccataat
    48661 tatagtttgt ccattgtctc tgtttatttt attcagtaaa tctattattt ctatccctgt
    48721 tttactatct aaatttccag taggctcatc agcaaataaa atctctggtt ttccaattaa
    48781 agctcgagct atagcaacac gttgttgctg accaccagat aactctcgtg gtgtatgttt
    48841 acgtctatca gttaaaccaa ctatatctaa gatttcatct aattgatttt tataatcttt
    48901 taaattttta ccatctaata acaaaggaag cattatattt tcctctacat ttaaatttgg
    48961 tattaagtta taaaattgaa atacgaatcc tatatttcta cgacgtatta tgctcatttt
    49021 ctcatcatta aaatgtgata tatcagctcc attcatatac acttttccgc tcgttggagt
    49081 atctaaacca cctaaaatat ataaaagagt acttttacca gaaccggatc gacccatgat
    49141 agaaacaaat tcacctttta ttacttgtaa agatacctct tttaacactc gagttgttgt
    49201 atttccaatt ttatattctt tgataatatt ttttgcttct acagctaaac tattatgtgt
    49261 aattttcata ctaacctcca taattattca aacttaattt cttctatcag tttcattttc
    49321 ttccctttta taataggcac tatcgaacct attaaagtta ctataattcc caataaccca
    49381 acaataataa atgttttaaa atctaaatct ggtttcattg aaatttttgg tcctgcaact
    49441 ataaagatag tttgaatctc aagtatagat atcacaatac caataacagc tccaagtaaa
    49501 cctgaagtaa acccttcaat caatgtcact tttatatttt gtttatcact tagtcctata
    49561 gatttataca tagctataga acgtcttttt tgaatataat taatcagtag attattaata
    49621 atacctactg tagcaagaag aaaaatgaaa taggtcatct tattcatagg agacaaaaaa
    49681 ctacttatag tatttaaaga atcattatta aattcttcaa ctgtacgact ccaattatat
    49741 gtatctccaa ataaatatct tatctgaatc ataacaacat ctggattgac tgctgtatat
    49801 actaaaaaac cataattagt tttatcaaaa tcattaactg cataatgtga tggtataaca
    49861 gcttctacat catttgcacg ggatttaaaa ctacctacta ttttataaga aaaatcatac
    49921 ttatcattag atagagttat tgtatctcct atagataagc ctactttttt tagagtatct
    49981 tcattcaaaa taacagaacg tttatcatta aaagcttcta ttacttgttt ttttatctca
    50041 aaatttgtat aattgattcc aaacatagag ttatatagtt ttatattatc tgtaccctct
    50101 agtcttgata atgttacacc attaccagaa atctcattat tcataacata aagaggtaat
    50161 atttttttaa ttccatccat atgtctaaca tcttcaataa actcttcatt catctttcca
    50221 tctgcaaaac cttgtaattc tgcgtcacga aacacatctg ttatataagt tttaacaaag
    50281 ttaccaacaa cacttattgc aataactgca gaaatactta taaatagtaa agtgatattc
    50341 tgtattatat ttttgttatt tttcatattt ctagcagcta atttaccctc attccctaaa
    50401 atatttttat aaacaaactc aaaaactata gacatgatat cagtaataag aggaatcaac
    50461 acaatagtag ctacaattaa tcctagtaat gaaaatccac cagctagata caatgtattt
    50521 tcaggggata ttcttggaag taaaatagat aaaataaaca ttatacttcc tataaaaagt
    50581 atagaacgat ttgaaacatt cttttcttct actgttccta gtacaatatt ttttattggc
    50641 aaatggctag cttttttaac aggtatatat gcactaaatg aagaaacgat tattgctact
    50701 ataacagata taatcactcc aatgggtgat attactactg gaattgatat tccttgttcg
    50761 agagaatttc ctaacccatg aagcattaaa tttaaaacaa ctacaccaat aggaatagca
    50821 attaatcctc ctatacttcc gtataatata ctttcaagca tcaatatacg agttacagtt
    50881 ttttcattgg caccaatact tctaaatgtt ccaataaaag gaagacgttc taatgtaata
    50941 accttataac tgctgtatat gataaatata ctaagggtta acgcaaaaaa acttattaaa
    51001 aagaaaggca ttgtcttttg tctagcatct gaaattatct tagtttcatt tatagtattt
    51061 gataccatat atttttcagt agaaagttct tcggataatt tatttactag attttctgtc
    51121 atttcttctt ctgactctat aagaactctt gtatatccac tgcctttatt tataattttt
    51181 gatagagtct ctttgggtag cagtgcattt acacctcttg tgttcctcaa aaatactgta
    51241 tcataagatg caatatcact aacttgaaaa gtataagact ttccataaat ctgtaaagta
    51301 atagaatcac ctttttttat tttatatttt gatgtaaagc gatttggaag aataatttta
    51361 tcaccagaaa aatcagtaat actatcgcca ttttctaatc gtggcttgtt gattttattt
    51421 agttgactta agtctgctga tataagacta aattcttcat agtatccccc tttattataa
    51481 atagcagagc tttccaatac accaaccttt gattttatag catttaaatc aggtatgtct
    51541 tctaaattgg ttaatatatc tggattttta ctttggacag atatagtcgc tgtaccatac
    51601 ataccttttg ccatttttct ttgtgcactt tcataagata atccaattga gaatgaaaca
    51661 aaaagtaaaa ctgttgataa aactagggac aataacataa ctgctgttct aatttttcgt
    51721 tctttaatat ttgtgaaaat atactttaat ataattttca aatttacacc ttcttccctt
    51781 atctaagata tttcaatcta atatttttat actttaatct aaattaaatc tctaatagac
    51841 tcctccatat ttttatcatt ctatttataa tatttttaat caaatcacct cttaaataaa
    51901 aaagattgat aaactactat ataaatataa taatctatca accttaatat attttttatt
    51961 tgaccttaat taaccttaat taaataggaa aggtgatata aaatgagcta cctaatccag
    52021 gtatactttc aacagatata ttccctccat gaacttcaat aatttgcttc gttattgcta
    52081 gtcctaaacc agttccttct attttttgtt ttgtattgct tcctctataa taacgattaa
    52141 acaaatttga tgcttcttct cttgacatcc cttttccatt atcagatata atgatttcaa
    52201 ttctttcatt taatgttata tgtacacaaa ctttagtatt tttatctcca tatgtaaaag
    52261 cattgacaat aagattacta aaagctcgtt ttaatagtgt acaatcaaaa tcaaagttaa
    52321 tattatctat attactctta aattcaacta tatttgattc atattctgga taatttaaaa
    52381 tatcaatgga taattctttc aagaatctta ctaaatcata attattttta tttaaaggaa
    52441 ttattccatt ttttaattga taggttaatt ttaaatcgtt tataagtgta tttgtatatt
    52501 ctatgttctt taacatgatt gaagcatatt tatatacttt ttcaggtgaa taattagtac
    52561 tactatctgt aagaagctct gcatatcctt ttattggtga aagtggagtt tttaaatcat
    52621 gagttatatt tgaaatccac tcttctctca taatatcagt tttattttgt atctcatcac
    52681 ttttatgaat ttcttcattt aaaatattta aactattata tatatcagca aaaacacctt
    52741 taatattaac tggaagatag cttcgttttg aaatatcact aacagcagat gtaatatttg
    52801 atatgcactt tgttatccag taaccataag caattccaga aaccaaaatt attaaaaata
    52861 taatccctat gattgaaaat acaattgact taccacctat aaatttacct ccatcaaaaa
    52921 acatattcac tttagatata tttaatggaa aatatataat ataaatatag tcatttttat
    52981 tatttttaat tgtattaaag tatacagttc cattacttga attattttgg ttagctaatg
    53041 ttaataattc agaattagaa taataatctt tatgctcttt tggttctaaa aacccataaa
    53101 ctctatttcc actagaatct aaaatttgca accacaattg attttctcga agcttttcta
    53161 atccagactg ttttacttgt ggcttattat ctataaatat gatttgttca ttaaagtttt
    53221 ctgtaaattt tttcggccag tcactacgaa taaattcccc atttggtttc tgaatagtaa
    53281 taagtgataa gaaaatacct attactgtca agattaagca aataaaaatc atgaaaaaaa
    53341 taatgtatga atgaaatact gttttataac tagatttatg catttaatca actcttttct
    53401 taaactttta ttttagtttg attattgctt atataaaata gacaataatt attgatatgt
    53461 aaaaatttat ttaaaaatac aactatctac ataaattata tttatataat tatatgttat
    53521 caagctgtct gttgtattta ataaatcctt ttgataacat ataaaagtaa gataaatttt
    53581 tccattaaat accttataat tatacacaaa atctctatat acgttaaaca gtatagagaa
    53641 aattttcata gaaccatctt tataggggat actttataaa agaataaaaa aattataata
    53701 tataaaaaac ttcataggag tgtaacaaca tcagtaaaga tatgaaaaca ctatataaaa
    53761 attcaaaaat attaagaata atgaaatatt tgaaattgct tatatcaaga aattttatat
    53821 aatataaact ggtcaaatat gttataatat taaattgtga caagttcatg gaggtgttta
    53881 tatgaaaaaa caaaagtcgc caattttact tgaaatgctt ggactatttt ttggttgtat
    53941 atcaatgagt attggtataa atatgttttt aaaaccacat acaattgctc ctggaggact
    54001 tagtggtcta tcattagtac taaacaaggt tacaggactt ccagtatcag ctatcatgtt
    54061 aattataggt gtcccattag taatacttgc ttttagaatt atgggtacaa aaaattcatt
    54121 aaaaacttta tttggaacag ttgtattttc agctatagtt caattaacag acccattatc
    54181 aaagctaaga tttactaatg acttattatt gtcttctatt gcaggaggaa tcctagttgg
    54241 tataggttta ggaataatgt ttaaatcaga tgcttctact ggaggaacag acttaattgc
    54301 actcatactt agtaagaaat tcccaggaat aaaagctaca aaattcatgt catgcctaga
    54361 tggaatggtt gttatatctt ctggtatagt aaatcgtagt ttagaaactg ctctttactc
    54421 tggtatagca ctttgtgtat taataaaaat agcagatatg ataatggaag gatttgacca
    54481 ttcaaaagca ttttttatta tctctgatga gcctgaaagt ttaagacaag ctataactga
    54541 agaacttgat agaggtctta ctattcttga tggtaaaggt ggatacacta gagaaaataa
    54601 agaagttcta ttagtcgtag tttctaaaaa acaagaactt tatctaaaga gattagttaa
    54661 aagaactgac cctactgcat ttgttattgt tacagatgta catgaggttc ttggagaagg
    54721 atttaaaaat ttagagaact aataaaaatt aatattttaa gtatatatac tattttaatt
    54781 aaaatacgat ttattcaaaa agagtgtctc ataaactttt tagttcatga gacactcttt
    54841 tttgtataaa atcaaatgca ttttcagtat tttaacaata aaaaacagga ttatctatat
    54901 tttgagtcaa ccactttatt gaaattttat ttagaaaaca atcattacta aataaccagc
    54961 atagatatta aatgattata tctattgttt tttcaattca tattgataac aaggaacatt
    55021 ttttacagta tttccagtat gaattttttt gatatacttt cctgtacatt taaatcctaa
    55081 taaatctaat gattttgtag aattttggtt ttcttcatag gttattgcaa ttattttatt
    55141 taagtttagt tctctaaatc catactgtat tactcttttt gttatctcag tagcaaaatc
    55201 atgtccccaa tagcttggat ttatacatat acctatttct gcttctaatg ctttaggatt
    55261 tatattatta aaccccatat tcccaataac tttattgtct cttttatata ctatagcaaa
    55321 gtggccaatt ttcccttttt tatagggatt tagaaaaaat gattttataa actttcttgt
    55381 atcttctaaa gatttatgct cactaaatgg taaatgtttt actactattt tatttttata
    55441 acagtcaaaa aaatcttcaa catcatctaa tgatgcaggt cttagtatac aacttctagt
    55501 ttctaaggtt ttcatttgag gatattcaga atcagacatt tctaatcccc ctttatacat
    55561 taatctaaat atactgttca tatttaaaat acgatattaa ttatataaat gttctcaaat
    55621 taaccttatc tttattttta ataaaaacta attactatat gaatctttca aatttacgaa
    55681 tttatctcta tttttatatt aaattacttg tgaaatatgt attctaaatt atatgttatt
    55741 agatatcatg cttaaaaatt ctttggttgc taaggataaa gatatatctt ttaaatggca
    55801 gtaacctata tttctcttag gtattggctc ttttatatct aatttaaaca atttctcatt
    55861 ttccaaataa tctatgctaa attcttctat aacacaagac actccaagat ttatatacgc
    55921 aaattctaaa agtaattcat gagaacccaa ttctatatcc gggtttagtt ttataccttt
    55981 tgataaaaaa tattcattta cataaagtct tgaatttgct ttattttcta gcattattaa
    56041 aggcaatgtg tttaattctt ctaatgatat tttcctacct ttgtattcta tgtaatcatt
    56101 tgcacataca aatatatcat gtatttcaat acactcaaca atatttagtg tatcatcttc
    56161 tattggcatg tttataattg ctatatctat attcccatct ttgagtaaag atataagttc
    56221 tctactcgtt ctatttattg tagatacatg tatatgtgga tacttcttat gaaaaatttc
    56281 taaatatttt aacaagaaaa aacgtgcagc tgtatctcct actcctattt tcagagaacc
    56341 gtattctaat tttttaaatt tatttattct atcttctcct gatgatatca actttaatgc
    56401 agtagtgaca tgttcactta gaattttccc ctctggagtt aattttactc ccttattgtt
    56461 tctataaaat aataaagtat ctaattgttc ttctaattgc tttattgact ggcttacagc
    56521 tggctgtgac ataaacaatt ccttagcagc aagagaaaaa ctcttattat ttacaactgc
    56581 attaaaaacc ttataaagtt caagttttat attcatatat aattactcct tatgtcaaat
    56641 attagtatta tttattttac ttataattat atttgaatta taatatacat ggtactaata
    56701 tgacaatatt aattctttag gaggatttta gataatggat agattagttg gaactgtttc
    56761 aagaggggtt agagcaccta ttataagaca aggagatgac ttagttaaaa tagttgttga
    56821 ttctgtttta aatgcgtcaa aaagtgaaaa ctttgaagtt agggacaaag atgtaattgc
    56881 cgttacagaa gctgttgtag ctagagcaca gggaaattat gctcacgttg acaatattgc
    56941 aaaagatgta aaagataaat ttggagatga tactgttggg gttatattcc caattttaag
    57001 tagaaatcgt tttgctatat gtttaaaagg aattgcaaaa ggatgtagaa aagtcgtatt
    57061 aatgttaagc tacccttctg atgaagttgg aaatcactta ataagtattg atgaacttga
    57121 tgataaggga ataaatcctt ggtcagatgt tttaacagaa gaaaaataca gagaactatt
    57181 tggatataac aagcatacat ttactggtgt agattatgtt gattattata agaatttaat
    57241 caaggattgt ggtgcagagg tagaaatagt atttgcaaac aatccaaaaa ctattcttaa
    57301 ctatacaaca agtattttaa cttgtgatat acatacaaga caaagaacaa agagaatttt
    57361 aagacaaaat ggagctaaaa aagtatattc acttgatgat ataatgacag caagtgtaga
    57421 tggtagtggt tacaatgacc agtatggact tttaggttca aacaaagcta cagaagaaac
    57481 agtaaaatta ttccctataa attgtgatga agttgtaaac aaaatccaag gtaatataaa
    57541 agaaataaca gggaaagatg tagaagtaat ggtttatgga gatggagctt ttaaagaccc
    57601 tgtaggtaaa atatgggaat tagctgaccc agtagtatct cctgcttata caaaagggct
    57661 agagggaact ccaaacgaag taaaattaaa atacttagca gataatgatt ttgctgactt
    57721 atctggtgat gagttaaaag aagcaatttc aaaatacata gttgaaaaag ataataaatc
    57781 tgatgattta acaggaaaca tggtttctca aggtactact ccaagaagat taacagacct
    57841 tataggttct ttagcagatt taacatctgg aagtggagat aagggtactc ctattattta
    57901 catacaagga tatttcgata actatacaaa atagtatgtt ttaataagat ttaatttttt
    57961 tggattatat atattaacat gaaaatttat taaaacctct taatagatat gacttttcaa
    58021 gagttatatc tattaagagg tttatttaat gttcacagat aagatatatt taaatacttt
    58081 aaacaagatt gtcataaagt tatataatct taaaaattta tataactcta attcttattt
    58141 atttctgaaa taatatcact cttcaaaatt tgtcttactg gaataattac agcaactata
    58201 ctaatagtga tatttaaaat aatcatacct atgtatagag gtgtatttat tttaagaatt
    58261 ggatttatat ataaatatac acgttttacc ataaaataaa tcataaattg tccaataaca
    58321 cttccaatta ccattataat acttgcatag aatccatata aaaaaccttc tcttatcatc
    58381 ataagtaaaa acttattatc cgtaataccc atagctctta aaattccaaa ctcatgtctt
    58441 cttgaaaaaa ttaagtagct tactgtattg attatatgga acaaacttat tgcaagaagt
    58501 acaaatacaa taccatatat aaataagagt ttttgattta agtaggtatt atttttttca
    58561 atagcaatgg tataatctgt tacgatacat ctttttacat cacttacaac actttttatg
    58621 ttctcagaca attcctcact gttactatct tctgtctttt ttatacttac tgaattataa
    58681 ttttcgatat caaagttatt tttcatttgc ccattcgtca taactatatc cataccataa
    58741 tcaccaatga aatatatgtt atttgccatc acacgtttta cagtagcagc aactacaaat
    58801 tcttttgttg tataatcatt cttattttct tctttaaatt taacaatttc acctgttggt
    58861 ttcattgtct ttggcacttt aacttttatt gtatctcctg gatttatatc aactgcatca
    58921 tacatcccag ttccatccat aggtagtcta actataacct tattattttt aaccatatca
    58981 tgggtattaa tctccccatc tataatataa gaatttaatc cttctaacat accattgtta
    59041 taaccataaa tatttgtttt taaaagatag ccaccttcat tttgctttgt acaaatacca
    59101 tcaaaaaaag tctttatcct gtaatctttt tcaagaggtt taaagaaatt tttccaaaat
    59161 agttgttctt ctttaatttg catagctcca aataaatatc ttactggata gacttttgat
    59221 attccctcaa cattgtttaa tcttgccatt ttatcttttg gtatacctac atcaaaatct
    59281 gttgtttgca tagttatttg gtagtcagaa tttaaaccat catcagcttt cattgtaagt
    59341 tcattattgt ttttagtaag ctgtatagag taactagaac atagaaatat aattccacca
    59401 agtgataatg aaaacaaaat tccaataaac attccccttt tttgagtcat gtatttatga
    59461 gataatactt ttgtcatgtt agagtgtttt acactttcta atattctctt tttcgtatta
    59521 gtaatcttaa agtttttcat agattctata ctagagtatt tattcaactg atgtacaaca
    59581 cgtacagcaa ttaaaattaa caacaataag ataaataaaa agcctaaata aatagatttt
    59641 tcacttataa aaaatgctcc tggaacaata tcactactca aaaatatatg tggaaattgt
    59701 tcatatattg tagacgctac tccaatacct aagaagcaac ctataggaaa tccaacaata
    59761 aaaagtaaaa ataactctaa aaatagtaga aataaaagtt gtttattatt agcgcctaat
    59821 acttctaaaa ccccatattg tgatattctc tgaagtattg aaacatggaa aatactatat
    59881 actgctgctg caccaaacac tccaacaagc aatataattg catttgtatt tagttctaaa
    59941 ttttttaaga actcaaatat attatatttt tctatattct ttggtggttt tactccaaat
    60001 tcaactgaaa gaggccagtt tatataagtt ttttcttttg atatgttgaa ttttttcata
    60061 aatttataat tttgcttttt aatattttta ttttcatcat attttacata aactatataa
    60121 gaatcctttt ctttaggctg caaataatcg tttacaaatc cctccatagt agtttctggg
    60181 tttgaaagac ttgataaaat accacataac ttatagattt tactatctaa attgatttct
    60241 gttccaattt ctttgtttac atttaaattg tttagagaat atgtgtcaag tactatctct
    60301 ccatctttac taggaagagt tccttttaat aattttctac ctgtcatgtc taaatatgaa
    60361 gaatcagcat ttaaaaattc tataataaaa ggttcatcta tctgattttt aggttttgta
    60421 acgccaagtc tatctacaat gtattccttt gattttttat tttttttaat tttattaagt
    60481 tgttccttat ctactttata gaaataatga taatctccac tatcttccct tatcttttca
    60541 attctacttt tgtctgcact atgaactaaa gaaccaattc ccgtcaataa tgctactgat
    60601 agtactatgc ttaaaactat agatatagat tgttttttat aatgctttat atattgaatt
    60661 gaaaatttta ctagagacat catagtactt caccaccagt attcaccaca actccatctt
    60721 caatatggat aattgagtcg catacttgtg ctatattttc attgtgtgtt accataagta
    60781 tcgtttgatg gaattttgca ctactttctt ttaataaaca taccacttcc attgtagttt
    60841 tactatcgag atttcctgtt ggttcatctg ctaatataag cgcaggttta tttgccaaag
    60901 ctctagcaat tgctaccctc tgttgttgac caccagatag ttcgcttgga aattttaaac
    60961 gcttatccca aattcccaat gtcttcatca gcatttcaat atattcatgg tctatatggt
    61021 ttcctttatc taatgtaaca ggaagagcta tattatcata agtgtttaat acgggcatta
    61081 aactgtagtt ttgaaatata aagcctatat ttcttcttct aaatactgtc aaatcttttt
    61141 ttcctatttt agatatgttc tttcctttaa ttattacatc acctgaggtt ggattatcta
    61201 atccacctat aatatttaac aatgtgcttt ttccagaacc agaagttcca actatagcag
    61261 taaatgtatc tcgttcaatt tctatactta ctccatttaa ggcttttact ttagtctcac
    61321 cttttccata gtgtttcact aaattattcg tcactaatat actcatttaa tttctccttt
    61381 caatacagat atatgttcta taaaatattg taagtgacga taattacact catcctacaa
    61441 agttagttta aactcttaca attctgtaag aatatactaa aacaacatcc acttcctagt
    61501 ttagattcta ctataatgtt tccattttct ttttctaaaa ttaatcttgt aagatataga
    61561 ccaatccctg tgccattttg attttccaca tttttacttc tgtaaaatct tttaaaaata
    61621 tcatttagtt ctctactatc aatacctatt ccttcatctt taatagtaat cttcgtatat
    61681 agctccattt ttattacaga aatagtaatc gtgctatctg atggtgagta ttttattgca
    61741 ttttctaaaa catttacaat tgcttctatg gtccactttt tattatgaac taactttata
    61801 tctgaaaatg gttcgagatt tatccttata tttttagctt ctgctttatt aaagatagta
    61861 ctgatacttt gaataagagt atctttaatt agtagttctt ctacttcaaa ttctataact
    61921 ccatcctcta atttagtcat tttaaataag gattgtaaca accagtcaat cttaaaagtt
    61981 tcatttttca tcttttgtaa aaactccttc ttctgtaatg tggaaatatt tatattctcc
    62041 agaagttcac aataaatggt tatatttgaa agtggagttt ttaattgatg tgacatattt
    62101 gatattaaac ctttaatcgc ttctttttct gactttgact gttctacctc tatttctatc
    62161 atatccttaa ttttttttac ttggtgagaa atttttgacg ctcttgtatc cttcgtatct
    62221 ggataagtaa cttctttacc ttccaatatt tgatttaaca ttaaacttaa ttcatcatat
    62281 cttttttgat ttattttagt agatactata aatataacaa ctgtacatat tataaaggct
    62341 aatataaaca tattattcta cctcattcca taaataaccc attccataag ctgtttttat
    62401 atattttgga ttagatgggt catcctctac ttttacccta agtcttctta tatttacaga
    62461 tacaatatta tcatcaacat aattttcttc gctgtcccaa atatggtgta aaatttgttc
    62521 ctttaataat atttgacctt tattttcaat tagataactt agaagcttat attctacaga
    62581 gctaagttcc aaacatgctt tatttttata tacttttagt aacttttggt ccaattttat
    62641 tccattggaa tatattactt tattattcga tttttttctt attgctactt tgactcttgc
    62701 ctttaataca gataaagaaa atggttttgt aatataatca tcaagcccta tttctaatcc
    62761 ttttacttca tcaatttctg agtctcttgc agtaagcatt ataattggta tatctgactt
    62821 ttcccttatt atttgacata catcaaatcc atctccatct ggaagattgc agtctaagat
    62881 tacaaaatct atatttttac tattaaatat atttaatcct tcttgttttg tataagcctt
    62941 aaatacatta aatccatcat tctcaaatgc ataaaaaaga ccttcattta agtttatatc
    63001 atcttcaata attaataagt tcaattttac tctcctttag attttttaga taaataatta
    63061 ttttcttgca ttatcatact aaaaatattt taattttatt tatttcacta aaaagattgt
    63121 atttaaattt gttttcaaaa taaaaacatc ataatcaagc atatagttat atatttccca
    63181 atttaattac gcttaaattg aaaatataac gttattctta tataattaaa ttatacaaca
    63241 ataaagttat attttttaaa tatattttta ctagggggaa tagaattgaa aagggttgat
    63301 gaaagaaata ctatgtttgc aagagcaaat tacaaaaaag atagtactgc ttataatgat
    63361 tattataaga aaaatcctga caaaaaagaa attgatgata gtataagaaa tagaccaaat
    63421 ttatgtagtg aaggaacaat gacttacaat gagttaaact ctccaatggc aagtagtgca
    63481 ttcgattttt tatctgatat caaatcttta tgcgaaggaa aagtttctga tactaaagta
    63541 gatgtagatg caaagtcaat gacaaaaaaa attaagggtc ttgcaaagca gtatggagct
    63601 tctgtagttg gtataactaa attaaaagac tatcatattt atacaaatag gggtagacat
    63661 gaagaaaatt acggtgaaga aattaatcta actcataagt atgcaattgt atttggatgt
    63721 gagatggata aagaaatgat aaatagagct ccaatgatat gtgaagttat agaaacatca
    63781 aagtgctatg tggatgcatc tatcgtcggc atgattttaa gttactatat aagaaattta
    63841 ggatatgatg ctagaaatca tatggatgct aattatttag taatgcctgt ttttatagct
    63901 cgtgatgctg gtttaggaga tataggaaga aatgctatac ttacaaataa agattatggc
    63961 tctagactta gattaggtgt tgttactaca gatattcctc ttttagaaga tgaatatgtt
    64021 gattttggac tagaagattt ttgtaaggtc tgtaaaaaat gctcttttaa ctgcccttct
    64081 cattcgcttt ctaatgatat taaaattggt gatgatggaa aatataattg ggtaattgaa
    64141 catgagacat gctatattaa atggagatat ttaggtacag attgtggtat gtgtatatct
    64201 gcttgcccat ttagccaaaa tctcgaaact ataaagaata ctacttcatt taagggtaat
    64261 aatgagctta ttcaaaaagc tttagatgag tatacttcaa aatttggtaa aagaatattt
    64321 atacctggaa atccatcttg gttgaaataa ttttatttaa taaagaatct gtactagaat
    64381 ttatcatagg acaggttctt tattaaatat ataaattttt aaatactttt tctcgtttat
    64441 aacaattcag caatgttttt agtctataat tgacattata aaatattaaa ctaaaaggag
    64501 taactgtatg gaaaaaatat tagtagtaga agatgattct atattaaata aaactctatc
    64561 atataaccta attgaagatg gatatataac tacttcaaaa tttacagcta aatctgcact
    64621 gaagtctatt tttgaatgtg aatttgattt aataattttg gatattaatt taccagataa
    64681 aagtgggttt gaattatgta atgaaataaa ggaaaattac aatataccaa taattttttt
    64741 aactgctaat gatatggaat gtgatatgat taaaggctat gaacttggag ctttggatta
    64801 tataacaaaa ccatttaata tcaatatatt taaacagaaa gttaaagctt ttttaaatca
    64861 tcttacaata aaaacaaaac aagatcacta tagggatgga tatcttgaaa ttaacttttc
    64921 tgagttatct gccaatataa atggaaatca aattatattt acaccattag aatatcgtac
    64981 tttaaaactg cttactgaaa atcctaaaag tattttaaca aggaaagtac ttttagaaaa
    65041 actctgggat atagatgcta actttgtaga tgaacatact ttaacatctg ttataagtag
    65101 gattagaagc aaaattgaaa aagacaatct taagtatatc aaaacggtat atggtatggg
    65161 atatatgtgg ttaggtgaaa gaaatgaatt ttaaaaaatt ttcttttagt tctatttatt
    65221 taataattgc tgttggtata atttttacag ctattttatt taatatttca atttatctaa
    65281 taactgatga tttaaaacta attgctctat tattaatata tacaatagta ctttgtggat
    65341 ttatagcatt aataatattt ttacttcata aaaaaatagt tatattttgt tctaaaatat
    65401 gtcacacttt agatagtatg atgaatagtg aagacaatat tgaaattgaa ttagaagaag
    65461 aaactatttt atcacgtatc aatcacagat taattagaat gtatgaagtt attcaagaaa
    65521 atcgcaatag tattgctata gagaaagctg atttacaaga actagtttct gatatatctc
    65581 atcaaattaa aactcctatt gcaaatttaa aaatgattaa tactactcta ctaaatcaaa
    65641 catttaaaac agaaattcaa aaggattttt taatggatat ggaaaaccaa ttagataaat
    65701 tagatttttt aatgcaatct atggtaaaaa cctccagact agagacaggt ataatcacac
    65761 tatctaaaaa gaaaaattca atttatgaaa caattgctac agcacttagt ggaattttgt
    65821 ttgatgctga aaaaaagaat attgaagtta cagttgattg tgacccaaat ttatatataa
    65881 ttcatgacaa gaaatggact tctgaagcta tttttaatat attagataat gctgtaaaat
    65941 acacaaattc taatggtaag atacgtgtag ctacagaatg ttgggttatg tatacaaaaa
    66001 tagatattat tgataatgga aaaggaatat cagaaagtca tcaagcagaa atctttaaaa
    66061 gattttatcg tgaagaagat gtacatgaca tagaaggtat tggaataggt ctatatcttt
    66121 caagaaaaat tatatctctt caaggtggct atattaaagt tacatcagat attggaaaag
    66181 ggtcgacttt ttctatcttc ttacctaata aataaatttt taaatatttc atttgtaatg
    66241 attctgcaac attttggttt tatactgtat ttacaagatg ttaaggaggt attattatga
    66301 gtattttaca agtaattaat ttaaagaaat attatggaca aagttcaaac attacaaaag
    66361 ctcttgatgg tgtaactcta tctattgaaa aaggcgaatt tatttctatt gtaggtacat
    66421 ctggtagtgg caaatccaca ttattaaata tgatggggtg gaggtaatca ctttatagaa
    66481 gttgataaaa ggtggcaaat ccacattatt aaatatgatg ggaggattag ataatcctac
    66541 atctggaaag gttattataa agggtaaaga attatctact atgactgatg aacagcttac
    66601 aatctttaga cgcagaaata taggttttat atttcaaaat tataatcttg ttcctttact
    66661 taatgtatat gaaaatatta tcttaccaat aggattggat ggagagacca tagataagga
    66721 ttttataaat gaaattataa atatgctttc tcttgaagaa aaattatatg atatgccaag
    66781 taatctttct ggtgatcaac agcaacgtgt tgctatagct agagcacttg taacaaaacc
    66841 agctattata ctagctgatg aaccaacagg taaccttgat agtagaacta gttcagatgt
    66901 actgagttta cttaaagtga caagtaaaaa attcaaccaa acaattgtaa tgattacaca
    66961 caataatgaa attgcacaac taactgatag aattattcgt attgaagatg gaaaaattgt
    67021 taactaggag gtgtagtata tgtttagaaa taataatcgc acatttataa gaaaaatagc
    67081 tttaaatgat ttaaaaatta ataaacttaa aacatatctt tcaggtatca ttataatgat
    67141 ttctacatgt ttattattaa cagtgagctt agtttcatat aatgcttctg tagatttagt
    67201 taatgcatct ccatatcatg ctatatataa atctgtagat gaaaaagcaa aaaatatact
    67261 atataaagat aaaaacctta gtggcgtagg aacctacaaa ttaattggaa gtaataaaaa
    67321 gacagactgt attatgtcga ttgtttatgc agatgataca gcaattaaac ttatgaattt
    67381 tcaaccattg aaaggcaaac tgcctacaaa taaaaatgaa atttctattt cagaaaaata
    67441 tttacaggaa tttggtttag ataaagatat tggagatagc attaaattaa attattatga
    67501 tgatattacg aataaagaag ttcaatgtga ttttattatt gttggatttc tagaaaatta
    67561 ttatcaagat aatgccaagc aatactatac agtcgtttca aatgattatt ttaagaatat
    67621 agcttctaca cctttacaaa ataaaagtaa tacttttgac gagtcaagac ctgatactgt
    67681 agatgtatta gttaaactat cagaagaaaa tacagagaaa gattcagctt caattaagac
    67741 acagttaaag aaaattggtt tatctttagg tattaagaaa tataatatat acttaaatga
    67801 taactatatt gaatcaaatt taattgatgg tgagcagatt attacagttt tagtagttgg
    67861 aatagttgtt cttttttcta gtgtttttgt tatatatagt attttttata tttcagttgt
    67921 taattcagtt cagatgtatg ctaagttgaa atcgttaggt atgacttctt ttcagttaaa
    67981 aaaaattatt tctctacaag gaaatatttt gtcaattatt tttattccat taggggttat
    68041 agcttcttgt ataattgctt acataattca accattagca tggcaaatga tagctgattt
    68101 atttataatt ttaattttat cactggtaat gtttttaact gttagaattt ctttatttaa
    68161 accagctaga attatttcta aaatatctgc tattgaagcc atgcaatata cagaaactaa
    68221 atttagaaaa aaagcaaaaa attttagtta tataaatata aaaaatctag cattaaagaa
    68281 tatcgagtca aatagaaaga aaaatttgat tgcattaata tcgctaagca ttagtggagt
    68341 tttatttatt tcaatcgcta atcttgctaa ttcaatagat ttcaaaaaac aactatctca
    68401 acaatttgtc tataacgaag attatataat tagcattaag aatgataact tatatgagca
    68461 tattacagaa atccaacaaa ataatccact aacagattct cttaagaatg aaattaaatc
    68521 tattcatgga gtaaaaaaat taattgaatc caaatcaatt aaaagtaata ttataaaacc
    68581 ttacatcaaa gatagagacg aaaaacaatt tattactcta attaaaggta ttacgcctga
    68641 actttcaaaa tcacttgaag aatatattgt cagtggaaaa atagactata cacatttaga
    68701 ttcagatagt ttaattataa ataaatatag aacaaaatct tatggattaa atttaaaagt
    68761 tggagataca gttacattta atatctttag tggaaatgat attattaaaa agaaaatgaa
    68821 aattatagga atcattgaca attccaatac aggaggtatg ttttttgctt cagacaaaac
    68881 tttagaatct ctaacaccat ataatacaaa tttagatttt tctattttaa tagataaaaa
    68941 gcattctaaa gaagttgaag aaaagttgtt aagtataatt cagaaaaatt caaatttaat
    69001 gctttattca tatgaagatg attatagaat gattactaga gcatttcaat atataattat
    69061 agcttcatac atttttgttg gtttaatttc ttgctttggt atactaaata tgaccaatac
    69121 cctaataaac agcgttttaa ttagaaaaaa agagtttgcc ttacttcaag ccgttggaat
    69181 gacaagaaag caactgcgaa atatgcttta tagagaaggt ctaaacataa gtatcaaagc
    69241 tatatgtact tcaagtatac taggttattt tggttcaaat ctactttgca cttttataaa
    69301 agatgtaatt agattagact ttattaattt taaattttct atatttacta ttttaatttt
    69361 ttcattcgta ttaattggta tacaagtttt agtgactgaa ttacttgtaa gaaatataga
    69421 aaaaaaatca cttacagaac gcttacgttc tcagtaagaa tgtatataaa aaatagctat
    69481 tttttataca agttttaata tgatttttta aaagctaaag ggagagaaaa ttttgacttt
    69541 acataatttt ctctccctat acttgttttt attttataca gatacacttc cttatatctc
    69601 caagcaacat caccagagac ataaacaagc atattcctta ttttctaaat atgtcaattg
    69661 catgacttgt aactcctact aaatcttcac gttcacaagt agcaaggtga tattttaaat
    69721 ataacgcaaa tgcatcatca tccatagagt ctactgcttc acgcatatac aaagccaaac
    69781 catctgatgc gacataatgc agtctagtta cattaaatgc agacatcaaa tcatcaatgt
    69841 tttctttacg tacaagctca aacaaatcct ttggttcaga cttagcagca aatgtctgtg
    69901 gatcaatcaa acctttttca atatattcag atacattaat atttcctcta tggaacccct
    69961 cgtcaatgag acagccatca gatataacgt atgcagcaaa aaccacacca ccaggttttg
    70021 ttacacgaat tgcctcatgt aaagcttgtt gtttatcttc tttgttataa agatgatata
    70081 gtggtcctaa cagtaacgta atatcatatt tattatctgg gaaaacagat aaatccatag
    70141 cattaccctg agtaatgctt atattttcat ttgattgagt atttttatgg aaaacctcta
    70201 tattatgttc gactaattcc actgcgtcaa catcatatcc ctgacgtgcc agtgtgtgag
    70261 aataacgacc agttgcagcg ccaatttcaa gcacacaatc acctgatttt atgtacttat
    70321 caatgtaatg catagtagtg agaaattcca ccattccatg ttttaatgca agtcgactat
    70381 cttcatcata agtattataa aagtcaatta agtattgttt tgtttccata atctcacctc
    70441 ttctatatta gttaataaac atcaaataga caaattccaa tctggttttt cttgtcttat
    70501 aaaagctgtt aatatatttt tcaacatttt ttcagcacta tatctatcta atgttaattt
    70561 ttttgttgct gttaagacag ctatgccatg agtataaaga aataaatcta aaaatattac
    70621 ttttgcacat tccaactcta ttccaatgct ttccgaaaaa agtcttgcct ttttttcatt
    70681 gtcaatttct ttataaaaat cattcgcctc tttcatcatc aaatctaaat catttataaa
    70741 taacaactta aataaatacg tttcttcttg agcaaattca atgtatgaaa gcggaagcag
    70801 taaataaggg cttacacttt tagaattacg ataattaaca acatactgat tataatattc
    70861 atatgcaaaa gcaagaaatt cattttttaa ttcattcatg ttttcgtaac aagtaaaaat
    70921 tggtcgagtg gaacactgta atttacttgc aatactcctc gcatttacag cttcaaatcc
    70981 cacttctctt gtaatatcca agactgtatt caaaatcatt tcttttgtta tctttacttt
    71041 aggtggcata tatgttcacc tctccattaa atttttataa aacacatatg ttatataact
    71101 atagtaacat atcaagaaat tatgtcaaga aaaagctttg catttttttg caattcctaa
    71161 aacttataaa taaaacatga gttgcaatta atctattaat agataacagc aactcatatt
    71221 ttcctttaaa tactcttctt tttgtctaat atttcatata cacaatcttc tattgaatta
    71281 atatcttttt cttttctttt tttagaatca attaaaatga aatacagtat aaaacctaca
    71341 gcaagtcccc atgttccgcc tttagcagca attacacctc ccataagtcc aatcaatccc
    71401 ttctcaacac ctgtattaca tagctccatt gatagctttg tacataaata tccttgaact
    71461 aaaagtgtta ctgacaatgc taatggtata agaggtgtag caatctgcgc aattggataa
    71521 aaacagataa aaattgctga aacccatact aatgtaccca tgccactaaa aacagactgc
    71581 atggcttcct ttccaacctt gtacctttga gcaacacttc ctgtaagtgt cgcagctaat
    71641 ggaccgcaca ttggtatata tggagaaaag attgccataa aaatatttct tatcccactt
    71701 ataacattag acctatttga attgaaatct atatattcat cttttctatt ttcactttca
    71761 gaaagtacta agttttcacc tgttataaaa tcaccaaagg caattatgta tatcataaaa
    71821 gccattggta tcccttgtat aaataacatt acacttggaa aacctattcc aaaaggagat
    71881 actgtattta tcagattttt aaaatctact atgtaaacta aattgtcaaa actaaatcta
    71941 ggaatttcta tttctttact aaatatacct actattaaac tcactaaaat agctgatact
    72001 acaccatatt ctcctaaatg aaataaaaat ttattcttaa cttttagagt atcaaatctt
    72061 tcagaaaaca ttacaaaaca agcaaccaaa attcctactg ttatagatat aggataagaa
    72121 tcaaatctcc ctttaggatt aaactctgat attatagtcg atataccgac acccattagt
    72181 attccacctt taatagaatt tggtatctta ctaactaact ttccagctac accagttata
    72241 cccattaaaa taaatattat tcctaaatct atttgtaaag ctgttaatgc ttgtattctt
    72301 tcaatgccca tgctgaactt taacaaatat gcagttgtaa gagttataga agctgtaatc
    72361 cagccaggta caactgggtc tcccataaaa acatgcaaac agtataatat tgagttaata
    72421 atagccatac tccatgccac ttcatagggt aatcccaaaa tttgtgtact aaggccaatt
    72481 gtgcctaaac ttgtcatact tgatattata ccttgaatag cttctggttt ctcaaatctg
    72541 taatgtataa atggaattct tatcttaaac attccaaatt ttatatgagg ttgttccctt
    72601 ctagcgagtc tttccataac ttcactccac ctttcaataa ctcttataag tttacaactt
    72661 tataattgtt tataaattgt caatgtcatt aaaattagta tataacatgc aaattatata
    72721 aacaataaat taaatctata aaattgatag attttgtgca tatatagaaa gaccgcttca
    72781 tttttagtta cttaaatcac ttaatattag ttatttaaat cacttgataa aggtttttta
    72841 taaaattcaa tagttctatt ccatgattca aactgtcctt ttgaatttcc ttctacagtt
    72901 ccacctgaag aaaaaatccc tccactcata ctcatacata aagtctcctt tagaggcata
    72961 atatatggaa ttggtaacgg atgacccata ttattgtatg ttaataattc tacgttatat
    73021 ggataattat tttcttcaaa gatttctaat gcctctaaac aagcttcata actattccat
    73081 atgttatctt cttttccagc aatcataagt atatctgctt tggaattttc tatttttatt
    73141 ctagcctctt ttctattctc tgctctttta agacttttct tataagtact attaaatcca
    73201 aatggaatac cttttgatat attttttttc tgttcttcaa agaatatatc attgtctact
    73261 ttgatatatg gaaatggctc tcctttatat gaccatgatg aagtatcatt tccactcatc
    73321 aatccattaa gagcttggaa acaataaatg tgaggttgtg atactacaac ctttttaatt
    73381 tgttcatatc ttgaagcaag taaaaaggcc aattctccac cctttgatgt cccatgtaca
    73441 aatatttctt tagtactggt aatttcattt tcactaatcc actcaaatac tttttcaaaa
    73501 tattctaatg gaacctcttc taatttatct ggtaaccctt ctaaagcaaa gtatgcaact
    73561 gttagtacat tgaatcctct agatgcaagt ggagctgcta aaaggtctag agcgtctaaa
    73621 tttccatcag aaccacctag cattaaaatt gttttattat tagaattttg tttataaaat
    73681 aattttccta taaactcatc agatatgtat tttgtggtaa tatcttctga tttaaatatt
    73741 ctctttaatt caacttcttt tctttcagta gaagtttcaa atatcatatt cataattatt
    73801 ggtttatcaa tagatatatt ttctgcaaaa tttttacctt cagttttaga tttttccagc
    73861 gaataaatta accccataca attatcagcc ttataagtac cttctatagg ttcaactaaa
    73921 tctaaatcta cttctccttt ttcatttgaa caaaacactc cataagatga aaattcttct
    73981 cccttgcacc atggaaattc cattttcaca cttattttaa gtttagtatt tggaattaag
    74041 tctgaaacca taatcttaag tctttcatcc acaaatgatt ctacattgta tacatttact
    74101 ttcataatct atttctcctt ataataatta tttatgcttt atatataaaa caactttatc
    74161 taatacaaca taaataaatt tttaaattaa gacaccatat tgactatttc attttatcaa
    74221 catatttcat ttttgtcaat atattgtctt ttttagtaat ttaaaattat gtagtctata
    74281 tgaaatccag ttgatttttg gctaattaaa gataggaatg ctattaggtt taaaatatat
    74341 ctattcaaaa taaaaaacca ctcattttaa gaatggtttt taatataaac tatttgttat
    74401 taataaggat atttttttat ttaaatttat ataattgaac atctaatatt taatgtttaa
    74461 taaaattatg catttgcaaa agtatatatg gcattaactc ttgctacata taaattctca
    74521 tcactacatc caatatatct agcatatttt tcaatctttt cttttgcatt ttcaacatca
    74581 ttttcatcgc tctccattaa ctcatttata taaatatcca ttaatgacgc tttatattct
    74641 tttatatcat agcctaaaaa ttcagtcaat ctctcaattt ccttactaaa atctccatct
    74701 tcttttacca aaaattcgta tacatcttcc ctatatggat ttaaagttat tatttgtttt
    74761 actactttgc attcgtcagc cttcccaata aaaccatctt tataattatt aaataaggca
    74821 ttagattttt ttatagattc ttcatcaata taagaatgta ccgcagttat acgattttct
    74881 ataagggcat ctacaacagc ataatgaatt ttaaaacaat cattgtataa ataattgctc
    74941 attttcttta ttgtcgattc tatttctaag aagctagcgt gcccattttt tttattttta
    75001 tttggtataa taaaagtttt attcaaatta ttaaaaagtc tcttaaaatc taaatatttt
    75061 tcacaataaa cacttttaaa ggtatcgata tctatagtta taattccaaa acttactata
    75121 gtctcaattc ctttcttaaa agactcttct atatattttt ctcctaaact taaacctcta
    75181 tcagatattt gctttagatt ttgaaaacta tttaaacaat ctctctcaaa gtttttagat
    75241 atttccaaag catataattt aaagattttc cttatcttat tataattatt ttttgtatca
    75301 tcaaatctga taatagctcc atttacatca aaagtaatca ttgagtttta acctccccat
    75361 tagtttcatc aataaaataa atttaatata aactttataa tcataatatt aaacttattt
    75421 atactataat tattaatttg atgataaaag ctattttcct tctaaataaa aaatttgtct
    75481 aaagtttcta aaaaatttag acaaatctta ggttattatt ctttaaatta tttttaaatt
    75541 attccaaata caccaaataa tattggtata aatatagctg gtaacaaatt agctactttt
    75601 atattcgtta atttaagtac atttagacca agtcctataa ttaataaact tccagctgct
    75661 gtcatttctg tgactacagg atcacttaaa aatccattta aaaatgatgc tcccacacat
    75721 ataatacctt catacaaaaa tacagatatt gcagaaaaca ttacacctat acctaaagaa
    75781 gcagtaaata taattgaagc tattccatct ataacagatt ttacaaataa agtatcatga
    75841 cttcctgtaa gaccactttc taatgaacca actactgcca tggctcctat acagaataat
    75901 aaactagatg atataaaacc ctctgctata gaatcttttt tatttccttt agaaaattta
    75961 ctttgtaaaa aagcacccaa cttatttacc catttgtcaa tatctattaa ttctcctatc
    76021 agagcaccta cagctacgga tattattgtc actaatgtgt tttttccttc tagtgctcct
    76081 gatataccaa tgtacaatac acataaggca attccattca ttatagtatc acttactctt
    76141 tgaggtaatc ctccttttat tataagacct actatacatc cacctgcaat tgctagacta
    76201 tttgctatta ctccaaacat tttttctccc ctcgattagc taattgaaat ttatcctatt
    76261 attaaaacct aaacatctat actttgtatt ggatatttta aatattccaa aaattcttca
    76321 aaaccttttc tagatatatt tacagtttta gtatttatgt taggatgaaa atttaagtaa
    76381 tcttctttaa ttacatcttt atctatgtaa agctcaactt ttctttctgt atcatttatt
    76441 aatgaaaaag gatttacact tccaggaaga agtttaagta cattgtatag tctttcaggt
    76501 gaagcaaacg ataatctaga acttcctatc ttatctttaa gtgagtttaa atcaacttgt
    76561 ttttctcctt taactacaat aagataatac ttatttcctt tggcatttct taaaaataaa
    76621 tttttacatt gacacccctt tgttattcca tctaaaatga ctaattgctc tgctgtatat
    76681 acagcttcat gctctactac atcatattca acatttaatt tatccaaaat atcatatatt
    76741 ttagtttcat tcatgctaga ttcattttca tcttgttctt ttttattatt taaatcactc
    76801 atacttttct ccttaaacac ttcatcataa tatcattgtg aggtattatt ctactatagc
    76861 tattgctctt actggagctc catcagcatc attatactta aatggtgctg ctataaatag
    76921 aaatttttct ggaacatttt ctaaatttgt aagattttct atgattattt ttcctttttc
    76981 aaataaaata tgatgcactt caaatactga tgtgttatat ctatccactg atagcatatc
    77041 tattcctatg ccttttatat tagtattagc tatatagttt gcagcttctt ttgttaatgt
    77101 aggataacct acatagtact gctttttatc ccaaaatttt gaccaacctg atttaaatat
    77161 tataaaatca ctatttttta tttcatcttc atattttttt agatattcca attctatatt
    77221 ctcatttccc ttttcaagtt ccaatacata agctttccca acaaaatttt ctatatccaa
    77281 cttatctagg gtctcacctt tagtatacat atgtcttggt gaatccatat gagttccatt
    77341 gtgagaaaat acactaatta atgtttcttg ataaccattt tcttcaataa tagctacttt
    77401 cttgatatct ggtctattag gctctgcata tacaggcatg tcattatgtg tcacatgagt
    77461 taaatcaaaa accttcatct ttatataccc cctatgtttt tattttctat tatataccta
    77521 aattcacttt atttctatca gattttattc cattatatac catactacta tatatttttt
    77581 ataaacctca agggatttac cgaaaaatct tggaaagaat tatcagtaaa tataacatct
    77641 tcacccaaaa aacgtttata ccttccttct tctttcttta aagtaattct ctgtttttgt
    77701 gaatgattat taaaaaccat tatcttaaga ggaggttttt ttctattagt ctgcactctt
    77761 tttaacatgt attttatgtg catatcagct tcaggaaatg aatatccaca aaatattaaa
    77821 aggtcagtat ctcttaaagt tttttctgtt tcattccaaa cattacttaa aaatatgttt
    77881 gacatattct taaaatatgt tggtggcact ataataggtt ctgttaactc accacactct
    77941 aaacattttg tctctgaact attttcaata agcttcatga caccaccttc atgtggtgta
    78001 agagttacac tattacaaat ggggcaataa agccaattca atgacccatg tatcttatat
    78061 aatttgatta atggttcttt tggttttctc caatttaact cctctttaaa atttgtaaac
    78121 tccacaccat aatcaagcat aattggcaaa tcattcttat ctcttaatcc agtaactgta
    78181 ttgtctatat gtatatcata atttgcacta ataaaagtag tatcaagaag caaatcattt
    78241 tccaaaagat tttcaactaa aagtttatga tatttattat ctgttctagg tgtattatga
    78301 attgcttcag ccattagcag tattaaatat tgtcttaaaa aacgtatact atcacttctg
    78361 ttatttagat tttctagtcc aaaatttcta aatgcttctt ttctttgttc tgctaagtct
    78421 aaaagaccta aaacttcttc aaaggtagga aaatttgcat tatctatatt atcttttact
    78481 atatcaatat tgaacatctg tttaaagaaa atatacaatt ctctattcat tttggtatta
    78541 taatttgtgg gatttagttt tttaaaatat tcgctaaaaa gttcattttg aataggtaga
    78601 ttctctgctg ctgaagctcc tgctcctaaa aatattgcta ttttcatata gttcctccta
    78661 atataaatat tactcctatt tttatatcta ttaaatatcc atatcattta ttttatgata
    78721 caacaataaa gctgtctttt actagaaaaa atcctattac aagacagcct tatattatat
    78781 taaatcttta ataattcgta aatagaaaga gcatatattt gagtagcttt tataatatcc
    78841 tctactatta agtattcatt agcttggtgt tctgtttctg gttttcctgg aaaaatagct
    78901 ccaaatgcaa cacaattatc taaagctctt gcgtatgttg ctcctccaga tgaaagtggt
    78961 gttccatcaa gaccagtttc ttcttcatat acttttctaa gtgtcttaac aagaagagta
    79021 tcttctggaa catagattga atccaagaaa tcatattctt cataatttaa attgtattta
    79081 tctgtcattt tctttaactc ttttacaaaa tcatcctttt tgtatgttac tggaatcctt
    79141 acatctattc ctgcaaattc tttttcgtta tcaatagtta ctctacctat atttactgtt
    79201 agtttacctg atacatcatc cttgcaatta ggaattatat tgtttccatt agcatcttca
    79261 ccaataactt ctgctaaaaa cttaattata ttagaatcta tgcctatatt attaagagct
    79321 atacaaagtc tagccactgc atttatacca gtatcacttg ctgctgaatg gacacttttt
    79381 ccaattatac agattttatt accttcaaca gtatactcaa aatttaattt atcaagttct
    79441 ttttttaatt tatcagagta ttttccaata tagattgctt tacctggaac tgcatttaaa
    79501 gcctttccaa ctgacaactc tatatcactt ttgctatcac aagtcaaatg aacttgtaaa
    79561 agacctttct ctgcatttgt tattgggaat ctagaatctg gagtaaatcc atagtttggt
    79621 atttcttcat tattttcttt atatttattt atacatctcc aaagattttc ttcatcagcc
    79681 ccaaaaatga atcttatcct cttattaaag tctacattta aatccataag agctttcact
    79741 gcataaattg ctgatattgt aggtccttta tcatcttgtg ttcctcttcc atacaattta
    79801 ccatcttcta aaacagcttc aaatggaggg taattccagc tttctaaatc accttctgga
    79861 accacatcaa cgtgaccaag tatacctatc attttttcac cttgtcctat ttctgcatat
    79921 ccataatatc catctttgta tactgtctta aatcctaaag atttacataa gtctaatata
    79981 cctcttaaag ctttatctac attttcacca aatgggcaat tttcagttgc ttcagatata
    80041 acactaggta tttttacact ttcttgtatt gaagaaatca tttcatcttg tagagaattt
    80101 actttttctt taatttgctc tttcatatta tcacccttca attttcatca taatatacta
    80161 ataaatattt tgacctttta aaaaaaaaat atgcttattt tttcagtttt tttataaatt
    80221 caatcgcttt taaagtcccc atttttgaat ggtcaaatgt aagtccacct tgaaaataaa
    80281 cattataagg aggtcttatt ggagcatctg cacttaattc tatagaagaa ccttgtataa
    80341 atgctcctgc tgccattatg acttcacttt cgtatccagg catgtcccaa ggaacaggtt
    80401 ttacataaga atcgactggt gcagcttctt gtataccttc acaaaaactt attacttcat
    80461 cagcattatt aagtctaata cattgaataa tatcacttct taagtcatca tattttggta
    80521 atacatcata tcctaatttt tcaaaagctc ttgagcaaaa gatagctccc attacagcct
    80581 gagatactat ataaggcgcc aagaaaaaac cctgaagtac atttctagtt gttccaaaag
    80641 taagaccaca ttcttttcct attccaggag aagtcattct ataagatata agctcaatca
    80701 aatcttttct accagctata tatccacctg tcaatgcaag cccaccacca ggatttttta
    80761 ttaaagaacc agccataaca tctgctccaa catcagtagg ctctttggta tctaaaaact
    80821 caccataaca attatcaacc attactatag cttctggttt aacagacttt attacttcta
    80881 tagcttcttt tatatcacta attgaaagtg attttctcca agaatatcct tttgaccttt
    80941 gtatcataac gagtttagtt ctatcattta ttttgttttt aattccttct aaatctaagt
    81001 ttccatcctc taaaaaatct acatcatcat atgtaacacc atactctttc aatgaacctt
    81061 tttcttctct tatgcctata actccctcta aagtatcata tggtctacca gtaacagata
    81121 aaatttcatc tcctggtcta actatacctt gtatacataa agtaagtgca tgtgtaccat
    81181 ttacaattat tggtcttaca agagcatctt ctgtattaaa tactttagaa taaatttcct
    81241 ctattttttc acgaccaata tcattatatc catatcctgt agtccagtta aagtgcatat
    81301 cacttagttt agattcttgc atagctttta aaactttata ttgattatat tctcttattt
    81361 cttttatttc ttcaaactta tcttttatat cttccattat ttcttgcgat agtttaaaag
    81421 tatcatcatc tattccatag tagtctttta ataattcttt tgtctcatta agcattttat
    81481 cacctgtctc tttattattt tatttaaaca tgtaaaggag actattttac taaaacaaat
    81541 aaattatagt ttataagtta gtataagtct cctctcaatc atcttaaatt aaattaatta
    81601 tctatctgtt gttattatta ttgttgtttt ggttttgatt tgttagatta atatactttc
    81661 caggttgtat agttgataca gcatgtttat aaatcatgtt ttgttgtcta ttatcccctt
    81721 ctattaatat tatataacta tcaaacccct ttacaagccc tttaacttgc actccattaa
    81781 ctaaatatat agtaacaggt atcctttctt tccttgcatt atttaaaaac aaatcttgta
    81841 aatttaaaac tgtatttttc attagatttg taccctccca agattaaatt gaacttctaa
    81901 aatattccta ccttatattc tatataagtt atgacaaatt ttcaatatta agttgtatac
    81961 ttaaaaattt atatattatt ttatagaatc tttaatatat aagattattt cattttttaa
    82021 ttcgtctata ttttcatatt ggtctaaatc aaaccatttt gctgttttat atcttttaaa
    82081 ccatgttatc tgacgttttg cataccttct agaatctctt ttaattattt caatagcttc
    82141 ttcgtatgta tattctccat ccagatactt caatatctct ttataaccta taccttgcat
    82201 tgatatcata tcttttttaa atcccatact taaaagtttt tttacctctt caaccaatcc
    82261 atttttaatc ataatatcaa ctctcatatt tattctttga tacaaatgtt ctctatctct
    82321 atttagaact attattattg gttgatattc ttcattaaat tttaaatcac ttgaaaaatc
    82381 attcattttc ttaccactta gacaaacttc aagagctctt atgatccttt tagtattgtt
    82441 tttatggatt ctattagcag attcttcatc aagttctttt aacttattat gcatgtaatc
    82501 tattcccttt tcagcaagct gtttttgaag ttcttctctt aattcattat tggcatcaga
    82561 ttgtgcaaaa tccatattat atattaaaga gtttaaataa agtcctgtgc ctccagttac
    82621 taaaacacat tttccctttt catttatttc atgtatatat ttttttgctc tttgttgaaa
    82681 ctctgaaact gaaaatggat agtcaggctt aacttcatct ataaggtaat gcttcactcc
    82741 ttgcatctct tcctctgtaa cttttgcact tccaatatcc atatattcat atatttgcat
    82801 agaatcagct gaaattatct ctgcattcat atcttttgct aattttattg acaaatctgt
    82861 ttttccaaca gcagttggac ctgtaagtat tataagtggt atttttttca taacattcct
    82921 ttctatacat tttaaatatc caaatatttt acataattct tttaaacatt ttttctattt
    82981 ccgtcttaga tatttcgacc attataggtc ttccatgagg acatgtaaat ggattattac
    83041 acttttctag ctgttccaat agacttttta tttcaatatc atatatttta tcatttgctt
    83101 ttatagcaga cctacatgcc atagatgcaa atctctctcc ttttaaatca taattacttg
    83161 taatttcttc tatattatca attatttgaa gtataaattt ctcagtttca ggtactccaa
    83221 atatagtagg aacacatctt accattatat gattattgcc aaaaatttct agttcaaaac
    83281 caaatttcat aaataactcc aagttatttt caatttgaag catatctaca tttgatactt
    83341 caataaccac tgggtctaaa agtatttgca tattgatatc ttgtctatag aacttctcca
    83401 tatatctttc atatagtatt ctttcatgtg cagcatgttg atccaacaaa tacatagaat
    83461 cgtctttgct caaaattata taagtattaa atacaactcc aattacagaa tatccatata
    83521 aggaaaactt gcgttttgaa ctacacaagt attcttcttc actgtcctta atactatctc
    83581 ctaagtaata atttccttca tttttaattc catcaacttg aaactcttct tgtatattat
    83641 catttgcact atcttcactt agataattaa tgttttttac atcatcttct acacttgcat
    83701 ttaggacttc acttactgat tgaaattcat ttattggttt ttcacttgat aaagtcacaa
    83761 cttcaatgac ttcatcctta tctttagtaa tattactatt tttaggagta gattctaata
    83821 aatcattatt tcttaattta taatctgtac ttttttctct actgttaata gcgattctag
    83881 gttgtgtttt tttatcacta taagtagcat attttccaat aagatttgag tgtattaatt
    83941 taacctttaa aaaatctcta agttctatat acacttcttg ttctttttca aatttaattt
    84001 caagtttatt ggggtgtata tttacatcta tacatgatgg gtctacttct atatttaaga
    84061 agcacactgc atgtttacct attggaatta tagacttata actttctgtt attgcatcta
    84121 tgattatttt actttttaca aatcttttat ttatatagat atgttgtaag tttttatttg
    84181 aacggtatat attgttatta cctatatatc cattcatttt aaagtgattg cacttaaact
    84241 ctacatctat tatattttcc gttatttctt ttccatatat acttctaata gtgtttacaa
    84301 gttttccatc ccctggagta tttaacatct gtttattgtt atttgtatat ttaaattgaa
    84361 tgtttggatt acctattgca agtttattta tcaaatcact tatgtttata gtttctgcat
    84421 gagtagattt taaaaatttc tgtcttgctg gtgtattaaa gaaaatatct tttataatga
    84481 tggtagttcc attagtagaa cctattggtt cttttgatat tatttttccg ccttcaacat
    84541 atattttagt tcctattatt tcatctttag ttttagtcgt catttctaat tttgatacag
    84601 ctgaaataga tgccaatgct tctcctctaa aaccaagaga gtataaatca tacaaatcat
    84661 caattttttt aattttacta gtagcatgtc tcaaaaatga tttttcaact tcacttgaag
    84721 gtattcctat tccattatct gtaatcttaa ttagactttt tcctccatca attatatcta
    84781 tggaaatttt atttgcacct gcatcaatgg agttttcaat aagttctttt actacagaag
    84841 aaggtctttc tacaacttca cctgctgcta tcttatttat agtcaaatca tctaggatgt
    84901 taattatatt tttcattttt acacctctaa gattttattt cttttgcttt tctttgaaga
    84961 ttataaagag agtttatagc atctaatgga gtcatattta aaatatccag atttaaaatt
    85021 tcttctgata gtatatctct atttacacta tcaaaagaga tttgagttaa ggctacttct
    85081 tttacagaat cttcttgatt aattttctct ttatcatcat tttgcttcat taaagcaact
    85141 tcatcattta atgctttaaa tttagaattt aatttatcat aatccttttt tatatgtttg
    85201 tagtctttta ctataagttc atgttctatt tttagagatt catatttatt cttaaaatta
    85261 ctttgattta ccttaactaa ttcttcgtcc aaattactat taattatatt attgttttct
    85321 ttatctccat ttattgcaac actgttgtaa acatgatttt tttccaagtc tttaagtata
    85381 tattttgctc tttctatgac ttcgtctggt aatttagcta atttagcaac atatattcca
    85441 taactcttgt ctgctccctg aggaattatt tttcttaaaa atattattcc ttccccatct
    85501 tctttgactg ctattgaata atttttaacc tctttaaact cttcttctaa atcagtaagt
    85561 tcatgataat gtgttgcaaa taatgtctta catctaatat ttttttgaat atattccact
    85621 attgaccatg ctaaacttat cccatcatag gtactagttc cacgacctat ttcatctaat
    85681 ataactaaac ttctctctgt tgcatttttt aatataaggg atacttcgtt catctctacc
    85741 ataaaagtag attgaccttg agataaatcg tcactagctc caactcttgt aaatattcta
    85801 tctaatattg gaatatcagc agactctgct ggtacaaatg agcctatatg tgccataaga
    85861 gctattatag cagtttgtct catatatgtt gatttacctg acatattagg accagttatt
    85921 atgttaataa tgttttctcc acgatttaaa taagtatcat ttggaacgaa attttcctct
    85981 cctactatat tttcgacaac aggatgtcta ccatttctta tatcaagttt attattttca
    86041 tttattgctg gttttacata gttatttata tgtgcaactg ttgcaaggga cacaaaaaca
    86101 tctatattag ctatagtctt agccactttt tgtattctat ctatgttttt atatattgta
    86161 tctcttatct ctacaaatat ctcgtattct aaagatttaa tcttttcctc tgcatgtagt
    86221 atcttttctt ctatttcctt taattctgga gttatatatc tttctgcatt actaagtgtt
    86281 tgctttctta tatatgtctc atctagcttt gcctgtttaa agttggcttt tgttatttct
    86341 atataatatc caaaaacttt attaaatcct atttttaatg atttaactcc tgttttttct
    86401 ctttccctgt tttctatttc ctttacaaga aaggctccat tcttagaaat ctctcttagt
    86461 tccttaagtt catcactaaa atctgattta attatgtttc catcttttat ggttatcgta
    86521 ggttcttcta gaatagcttc atctattaaa ttgtatatat catctaattt atccatttct
    86581 gaaacatact cttttaggat ttttgcattt gataaattta tagtatcttt taaattaggt
    86641 aacttttcta tcgaattttt taagtgaatt aactcttttg gtgttactct ctcaaatgct
    86701 atctttccac atattctttc tatatcgtat atatttttaa gtatatcatt taggtcttct
    86761 cttaatataa agtcatcttt tatttcttct attacatcta atctattttc aattttagat
    86821 ttatttatca aaggttcttc tacatatttt cttaaaagtc tacctcccat tgctgtagaa
    86881 gttttatcaa gtacatgtaa taatgaacct tttttcttat tccctcttat agtttgagta
    86941 agttctaaat tagttctagt aaacatatct aaaaccatat attctgatga attgtatata
    87001 tttatattat taatgttaga tgttatttgt ttttgagtat tgtatatata attcagaaga
    87061 attgataagc ttgactttat tagaccttta tcatcaaact ttagtttttg tagataaaca
    87121 tctggaaaat attcttttaa tatatttata tccaaatagt tatcactaaa actttcattt
    87181 atgtatatat tacttacagt agctatatct ctaagctttt ctataaagtc taaatcattt
    87241 ataattattt cagttggatg gatttttgca atttcttcaa ttaccttatc ttcatttaaa
    87301 catgttgcat tagtttctcc tgtacttata tcaacataag ttagacctat attagtacca
    87361 tccttataca aagataataa ataattattc tttttatttt caagtaaatt tccatctaaa
    87421 actgtaccag gagtgatgac tcttataacc tctcttctaa caattccttt tgctgtagat
    87481 gggtcttcca tttgttcacc tattgctact ttatatccat tttcaactaa ttttgatata
    87541 tatgaattgg ctgagtggaa aggaacacca cacataggag cacgttcttc taaaccacaa
    87601 gcttttcctg tcaatgctat ttcaagagct tttgaagcta ctaatgcatc ttcaaaaaac
    87661 atttcataaa aatctccaag tctaaaaaac agtatacagt ctttatatct attttttact
    87721 tcaagatact gtttcatcat aggagttaat ttattcatat ctatttgcat tatcaaacct
    87781 ccttcttttc taattaaata ttatatcata gtagatgatt attattaaca caatatataa
    87841 aattttgaca tataactaaa aacaatccaa aatgtatact cacattttgg attgctaagt
    87901 ttaatgctta ttaaataaaa atatatatat ttttacaata aagatattat ttctttttta
    87961 agtttaatga tattttcaag gttatcttca tttaactttc tactatctat aacaaattct
    88021 ttctttacta ttgatggttt ttttgaaata acataaattc tgtttgatag cattatagct
    88081 tcgtcaatat catgagttat aagaagtatt gttgaattta cttttttctt aacatctaaa
    88141 agccattttt gcatggatgt tttagttaat gaatcaagtg ccccaaaagg ctcatctaaa
    88201 agcattatgt cattagaatt tataaaagtt ctcaagaagt tagctctctg tctcattcct
    88261 ccagaaagtt ctgaaggata tttatcttca tatccgctta atccaaacac ctcaaaataa
    88321 ggttttacca ttgacctagc tttactcttt ttttcttttt ttaaaattag tggtagtgac
    88381 acattatcta ttatagtttt atatggcaag agtaaatctt tttgatacat ataactatat
    88441 ttaccattta tattcacttt gccactatca taatctgtaa gtttagttat aatattaaaa
    88501 atagtacttt ttccacatcc acttggccct aatatagaaa caaactcacc ttcataaaca
    88561 tcaatactta tatcttttaa aacttcaata tctttataag tttttgatac attttctata
    88621 gatactttta cttttttatt gtggtaaaaa ttcatttgtg taagcatcac ttgccttcat
    88681 atccttatct attaatttat attcttttaa gaatgatgta tagttgttcc atacactatc
    88741 tttcatttct ccccatcgtg gtgcatcatc tttgtacttg cttgctaaat attcttgact
    88801 ctttaaagct agtttttcat ctacttcagg tgcatgtttt actaaaattt ttgctgattc
    88861 ttctggattt tttattgcat attcataacc ttttgttgta gcttttaaga attttttagc
    88921 aagctctgga ttatctttaa gcacagtttc attagaaatt ataagtggtg tataataatc
    88981 caatctctca tctaaatctt ttactggtat aaagtttaag tcatatccaa ttaaatcagc
    89041 tttaactgca tcccaacctt caaatatcca tgcaaaatct acagttttca tagctgcaaa
    89101 gaaatcatct tgaccagtat taactatctt taacttatta aaatcagctc catttttctt
    89161 cataactgct ttaaaaacag cttcttctga tggagagccc caaccaccat aagtttttcc
    89221 ttcaaaatct ttagctgttg ttatattctt ttcttttggt gatgcaaacc cagaagtatt
    89281 atgttgtata acagttgcta cagcttttat tggaagtgga tcttcactag tctttgcata
    89341 agtaacttgt tcttgatagc ttataccaaa gtcagctttt cctgttgcta ctaaagtttc
    89401 tgctccactt tcaggtggtt gtactatttc aacatccaaa ccttcttctt tatagtaacc
    89461 cttatcaagt gctacaaata atccagtatg atttgtattt ggtgtccaat caagcaccat
    89521 agttactttt ttagaagaag tatctttatc attgtttttg tctttattgt tatttgaaga
    89581 acatccagtt attgttgcca atgtaaaaac acttactaaa cctaatattc ctaacttttt
    89641 aaaattcata attgcctccc tcaaatacct ttaatcaatt aatctatgtc ttataacaac
    89701 tttttttaca gcctgtacaa ttcctacaaa cattaaacta aatataacta ctaatatagt
    89761 agatgcaaat actttatcaa gtgcatatgc actttttgac ctaagcatat aaacaccaag
    89821 tcctttcgtt ccacctagcc attctgcaac agttgctgcc attacagcat acgttgcaga
    89881 tattttaagt ccagaaaaaa atttatccat tgacatagga aatttaaggt gaatgaatgt
    89941 attaacttta tttgagtcca tagtcttaaa taaatttaaa taatctttat caatattctc
    90001 aatgccatct acaaaactta ttaatatagg aaaaaaacaa gtaagcatta ccatcaatac
    90061 ttttggcatt gttccaaatc caaaccatat cataaaaagt ggtgctataa ttattgtagg
    90121 tatcatctgt gtaaccaaca taataggata aagacatttt tttattattg atacaaaatc
    90181 catcaatatt ccaattacca atgatattat aattgcgact ataaaaccaa gtattgcttc
    90241 tcctatagta accacagcat gcatggataa attttgataa tctttaaaaa acacattaat
    90301 tatatctact ggtgtgggta gtatatactg aggaacttct aaaactccta ccatagattg
    90361 ccaaagaata agtataaaca aaaatgttgc tattggatat atactatctt tgactttatc
    90421 tatgatttct aagtttttca tctatagtca gacctccagc tttttcatct actctagcta
    90481 ctgttatgac tctttcacat ccaagattaa aagggatttt atgtaccttt tttaataatt
    90541 caaaaacttc atcaaaatca ccttcaacag tagtgctcat tgctcctatt tcacatttaa
    90601 gaccactttt ttcaatttca gcaatacaag catctactac tttatacatt tcttcttcac
    90661 ctttgtaagg tcttagtggc attactgcta tgtctgcgat taccatttaa atcactcctt
    90721 taaaaataat taatacctac taggtatatt tcgtttttta ttaaaaaatt ttattactaa
    90781 aaagatatta tatttaaata aaagaaaagt cttatccaaa ataggataag acttattttt
    90841 atcttaactg gtctccctac actggcatta tccaaacagg ttcaaagggt cgagataaaa
    90901 tctcctctca gcacattagc tccccgaaat atattatatc ttttctactt gattatacta
    90961 cacttatcat attttaacaa attttttatt tatattagat attttatcca ttcaaaaata
    91021 tctaatataa attgcacatt attacatcaa ataaattatc ttaaaacagt aatttatcag
    91081 tatcttccaa aactagatta actgaattat ctagttttta ttttgctatt tcaagcatat
    91141 ttggatgtat atcaattcca tacaaatatt gtactaaatt tctgttttcg ctcatctaat
    91201 ttgcaatcgt tacagattca ggttagacat agcttttaga ctctacttat ctttatctac
    91261 aaaaaatcct tcaataaatt cattaataat attcattaat ctaaaaataa acctctatct
    91321 ggatttttaa gatacaagcc tttcaggagt atcttttgtg agaatataaa aattactcgt
    91381 cattatcatc aaaatcctca gcaaccaaca ttttatataa gaatcaaact ctataatata
    91441 attattttat ccaatttatt tttgagaaat aaaatatttt tttaattttt aaatttttta
    91501 atatgcacct tgaaaaaaga aacgttttcc tatattatgg taatagtaga ataaaactaa
    91561 ataggcaaaa ctagagaaat ttagtgacgc aaagctatag ggactaagac ttatgaaatg
    91621 agttatgtca gccagttgcc aaagagatat tttctttttg tttttatgaa tgttttttag
    91681 ggggatatat gatatatgtt tatggataaa atggatagat gtacacatat actaactgca
    91741 tatatatgca gttcacgcga ttactgcaat tttatagata cacaattaaa tgattttata
    91801 ctagaatatg gagagaatgt ggtagaatct tgtttgcatc aagtgatggt attggtaagc
    91861 agatataatt aaagaaattt tattttctag aaaacccttt ttagttttat ctacgtttta
    91921 taattcatta aagaactaat taaaataagc ttcattatat atttttcatg aagtaaacag
    91981 ttgagtttat ctcatatact gtttacccca attacataat tctaataata tagattctaa
    92041 tgatttacca cgtttagtag acaaatattc aacttttgga ggaatagtcg gataagaaat
    92101 cctcttaata agtccatctc tttcaagata ctttaattct tgtgacagta tcttatgact
    92161 tatatgaaca acttcttttt ttaattgact gtaacgtatt ggctcttgtt ttaaaatatg
    92221 ccataaaata attgccctcc atttacttcc tatcacagtc atggtaaaac caattgaaca
    92281 attaaaatct ttttgtcttt cttcaatatt tggaaattct tcaaaattat tatctatatc
    92341 catctcaatc ctctctttca aaatagtaag tatctaacta aaaagtgcat tcttgtttag
    92401 cgtactaatt cgtaatataa tcttgattaa aaaatagcta tgcacactcg tgactttagt
    92461 catgagttag tagctaaaat agtca
//
LOCUS       DACTZW010000004        91682 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.004, whole genome shotgun sequence.
ACCESSION   DACTZW010000004 DACTZW010000000
VERSION     DACTZW010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 91682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 91682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..91682
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.004"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(145..1224)
                     /locus_tag="JAM15_01525"
     CDS             complement(145..1224)
                     /locus_tag="JAM15_01525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HAT6796953.1"
                     /translation="MSRRKKGISLVILVAIISSILSSFLTIILVKDNLVSKSTGSSTP
                     IVVNDDGKSQNIYQAVAEKATPSVVGITTTSVDTSNMFAIPTETQGVGTGIIVDSNGY
                     ILTNSHVISDGQATSVNVLFNDGSTTSGKVVWFDQQLDLAIVKVDKTGLTPAEFADSD
                     KVKVGDISIAIGNPLGLDFQKTVTQGIISGLDRTIQTEKTNMTGLLQTDASINAGNSG
                     GPLLNQKGQVIGINTAKASQAEGLGFAIPINTAKSIVEEVIKNGKYEKVTLGIKGTDV
                     SNYEAATGTKLSTDKGVYVAEVISGSSAEKAGVKVGDIITKVGDTDITGMNDLNKKLY
                     TFSKGASTKITVNRGGKAVTINVNF"
     gene            complement(1380..2729)
                     /locus_tag="JAM15_01530"
     CDS             complement(1380..2729)
                     /locus_tag="JAM15_01530"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003320779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HAT6796954.1"
                     /translation="MGKINFDYSKATEFFCQNEIDVMQPYVDVAHDMLHNKTGLGNTF
                     LGWIDLPKNYDKEEFDRIKKSAEKIKSDSDVLLVIGIGGSYLGSRAAIDMVSHSFRNG
                     LKKEQRKAPEVYFVGHNISSTYIMDLLDIIEGKDISVNVISKSGTTTEPALAFRIFKD
                     YLEKKYGKEEARKRIYATTDASKGALRQLATEEGYETFVIPDDVGGRFSVLTAVGLLP
                     IAAAGLDIDVMMKGANDAREAFQNPDLKSNDSYRYAVARTILHRKGKDVELLVNYEPQ
                     LHYVSEWWKQLYGESEGKENKGLFPASVDFSTDLHSMGQYIQDGKRLLFETVLNVENC
                     KRNITISSEEVDLDGLNYLAGKTVDFVNHKAFEGTLLAHTDGKVPNLVINIPQLDEYN
                     FGYLVYFFEKACGISGYLLGVNPFDQPGVEAYKKNMFALLGKPGYEKEKEELEKRLK"
     gene            complement(2994..4622)
                     /locus_tag="JAM15_01535"
     CDS             complement(2994..4622)
                     /locus_tag="JAM15_01535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HAT6796955.1"
                     /translation="MNIIISLMGGLGLFLYGMNLMGEGLQKSAGTKLKKIIKLLTSNL
                     FMGVLVGTGVTAVIQSSSATTVMVVGFVNAGIMTLKQAIGVIMGANIGTTVTAQLVSF
                     DLTGMAPVALGVGIILYLFGNKPRIKNIAEILIGFGILFTGMDFMKMAVEPLRDYQGF
                     TDLLVTFGRYPLLGLLLGFGITAIIQSSSASMGMLVALAAEGLVPLSAALPILYGQNI
                     GTCVTSLLSSIGANKNARRAAMMHLIFNVLGTVIFLIFLNKPVVSMVTSWDPSNVARQ
                     IANTHTLFNIISVLILLPFTNLIIKLAIKLVPDRAGDIDEDETKTIKYIDDRMIETPS
                     IALANTIKEALRMGEKAKESLNASMEALVEHSTEKIDKTYRRERLINDLQKAILNYLL
                     KLSKAPLDDDSREVVDTLFNTVNDIERIGDHAKNIAELSQVAIDSNISFSEEGQSELD
                     VMYNRVVSAYTYALESMRTDNVDLACKVIKIEEQVDIMEKSCRANHMYRLNNNLCSIE
                     NGVIYLDVISNLERISDHAVNIAQQVIAKRLGND"
     gene            complement(4746..6350)
                     /locus_tag="JAM15_01540"
     CDS             complement(4746..6350)
                     /locus_tag="JAM15_01540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796956.1"
                     /translation="MLRVSNVKLGIDKDISLLKDVVLKKLKIKEKNLVKYSIYKESID
                     ARKKGKMEFVYSVDVEVKDENKILNSKIKDVTKIKEIRYINVPVGDKKLKNNPLVIGS
                     GPAGLFAGLLLAQMGYEPIILERGLDVDSRTKDISDFWTTRKLKNNSNVQFGEGGAGT
                     FSDGKLTTRIKDIRCRKVLEELVQFGAPDEILYSHKPHVGTDILKNVVKNIRNEIISL
                     GGQVRFNSKVTDIVVSNDSIQSVIINDTEKIDTDTIILAVGHSARDTYEMLYSRGIKI
                     VQKPFAIGARVEHPQDLINKAQYKDFYNHPRLGAADYRLIEHVSNGRTAYTFCMCPGG
                     SVIASASNDFEIVTNGMSEHARDKINANSAFLVNVTPEDFKSDNPLAGVHFQQKYEKL
                     AFELGGKNYNAPVQLVGDFINNKTSLNLGSVEPSYRPGYTLTNLSECLPSFVTETMRE
                     AFISLDKKLNGFAMYDAVLTGVETRSSSPIRIVRDENTLESVSIKNLYPCGEGAGYAG
                     GIVTAAVDGIKCAEKIIQKYTNNTKI"
     gene            complement(6398..6715)
                     /locus_tag="JAM15_01545"
     CDS             complement(6398..6715)
                     /locus_tag="JAM15_01545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796957.1"
                     /translation="MDYIGIENITPYENTYEFSVYEYDDEITLGSEKLYVCELRVVLI
                     KVNSLYVERLHKSVEAMVLVKNLKKDLDKTLVVNKIKNFVLDEIWVENLVKENIEVIF
                     VES"
     gene            complement(6720..7085)
                     /locus_tag="JAM15_01550"
     CDS             complement(6720..7085)
                     /locus_tag="JAM15_01550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796958.1"
                     /translation="MSLSLGNAIAVSTNFIKSNPAVPVYNGEEIYAVIYHIEIGYNNG
                     VSPDTKQYIIIDYKEFDLSMDKKNELINVAKEYCKSKGIVENENLEINLLDNEEAENF
                     LEKVFNNMKVIRGLITKKG"
     gene            complement(7166..8203)
                     /locus_tag="JAM15_01555"
     CDS             complement(7166..8203)
                     /locus_tag="JAM15_01555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein translocase"
                     /protein_id="HAT6796959.1"
                     /translation="MLGRNELCPCGSGKKYKKCCLNKDIVSERACRKTELSQKQYTDL
                     YSKLYDYSRQDKFKEECEKAKEMFYIMQNDSVNEKFERFFNTYLIQDHIMENKKVMTV
                     GFLEENGANLSQSEVSILKSMFESYVSIYEVKEVSAGKIVLKDCLSGNELCTEDVKLL
                     RSFKIGSCMIARIVDIEGTNILIDITISISNEVKDIILKDIMNLFNQYQDVYKDMKSF
                     LIYHTHILYKYIQQLLDPSIAEYLKRERDKNDTKVNSENELAEEECKVLDTLKENVEK
                     ENIDACIEFWNEYKKNHENIKGAENGWAAAVEYYVKKEAGQPITQVQISKKYDISSST
                     LGKRYKDLKIS"
     gene            complement(8456..9040)
                     /locus_tag="JAM15_01560"
     CDS             complement(8456..9040)
                     /locus_tag="JAM15_01560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796960.1"
                     /translation="MRLNNREKNLLKILLILVIILASDIAVSYLEENLTSLKNEKQNI
                     INKINNQDNYQIKDNKHIDDKYIESVELNKNEELKNNFNNSFLDKKTNKDIVLLVENE
                     LRDIVNIEYINQESSLDNHNKKQVNLEIKVNGELENVLKLEGVMKKLRLNNKFEKIEI
                     NKLKVNNFDAQNIPNEYKQEKDNIVECKMTVRVI"
     gene            complement(9055..9498)
                     /locus_tag="JAM15_01565"
     CDS             complement(9055..9498)
                     /locus_tag="JAM15_01565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796961.1"
                     /translation="MKVDKTINFLNGFKKTKPCNKIYKIIIVLILTCILFKSFMYVKS
                     INELEDYINQNKLVGKSKHTLPTTDKTREKFSKIKLNEIKKIYETIGINSITKISIDK
                     NKLEMEGVCSDLDVLNNLRKIKYIKYYYIDSIVRDGEYYRFRIKS"
     gene            complement(9499..10371)
                     /locus_tag="JAM15_01570"
     CDS             complement(9499..10371)
                     /locus_tag="JAM15_01570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein PilM"
                     /protein_id="HAT6796962.1"
                     /translation="MAIIKKIINLEINDDYIRLVFLRKSHKKVFIDKSIIKEINFDIK
                     NDSNSIEKIKYIEDVVRFVKEEIGKSKILYKNLYFNIQIQDIVIRNVEVLNTKKKRDI
                     LSMIEFEITQYIPININNYSIKYKVINSKNDKLNIQVILFPKSIIQLIKNISENLNMN
                     PKTININFDILQKLINLNLIENFSEEGVFIECKKSQLIINITKDKKIRETYLLSKEGK
                     SYEFIKRLLRDFKYVYYYGIENCFIEEYFKYTDKSIEVNPLRLKDKVKVENNFDADLE
                     DNRINYINSIGMII"
     gene            complement(10424..10783)
                     /locus_tag="JAM15_01575"
     CDS             complement(10424..10783)
                     /locus_tag="JAM15_01575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HAT6796963.1"
                     /translation="MINLINKKRKGFTLVEMIVVVTILGVISSIALVKYSKVQESAKL
                     NADYTNAANIVTAASMAINDDEKTIDSLSVETLKEKGYLNTVPVPQSTSGKFELVIND
                     SGTDISVNINSKQFYPK"
     gene            complement(10837..11922)
                     /locus_tag="JAM15_01580"
     CDS             complement(10837..11922)
                     /locus_tag="JAM15_01580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HAT6796964.1"
                     /translation="MRLSKNIFYNLEKFYLVLNRISDKEIRVICKEIGILLESGCEIT
                     KIFEIIESQSSKKVKNLLSIVSNHIQKGNSIAESFQITGIFSKFFISMIKAGETSGNL
                     DIIMSDLSNYYDKEYKLKMKIITISIYPIILIILSILSMLFIFVFVIPNFQVVFTNNG
                     IEPPLITRVLMGISTVVTNNLAYIIFSFILFSIGSIYFFITNDNIKKLINSLKFKIPF
                     IKKINQLVATTRFSRALSVLISSGIQIVEAIDMSASVIDNEFIYERLKISNNYIKKGN
                     SIGKSLNLANVFPKLFISMANTGEESGKLDKSLNVINKFYENELNNKIEQIMKFIEPM
                     LIVFMGLIIGTFILAMVVPMFDAITNF"
     gene            complement(12093..13442)
                     /locus_tag="JAM15_01585"
     CDS             complement(12093..13442)
                     /locus_tag="JAM15_01585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HAT6796965.1"
                     /translation="MPMLIPEKLAKKYNVFPVEFQDDNLVVEIEDEDIYALQDLRLAT
                     GKEIILKKEKKELISEKIEKYYNSFELDEDYAKKLFENLLEKAIKENASDIHIEPFKE
                     HLIVRMRVDGELKEVSKFLVDVYPSLSTVIKLKASMDITEKRLPQDGRVDIKLGGNLI
                     DIRVSSIPTVYGEKIVLRILNRDTFLKDKLELGFSEEAIKSINRIINKRAGVLLVTGP
                     TGSGKTTTVYSLLNDLKGINKNIMTIENPVEYKMDGISQIQVNSKVGLSFDVGLRAIL
                     RQDPDIIMVGEIRDAETAKIAVRAAITGHLVISTLHTNDAVSSIARLLEMQIPPYLLN
                     ASLIGVISQKLVRKVCNHCSHEIMIKDNFSGDVNTKVAVGCEKCNDKGYFGRTAIYEI
                     LEINDDIKTCIRNMEDSSTIKDVAQNNGMITFEDSCKRLINEKITTLEECLVVNEMI"
     gene            complement(13465..14145)
                     /locus_tag="JAM15_01590"
     CDS             complement(13465..14145)
                     /locus_tag="JAM15_01590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HAT6796966.1"
                     /translation="MKKQYVFIILASTILGILVGTIFRDYSNEETVYTSKDKSIRKEI
                     KMTRKSIKELTKEKDKLDKEINSMKQNQKNSEEISEIETLRDSLSYSDVKGSGIILSI
                     DAIDEKTGNIANSIDYNKILVKVINELKVNGGKYIEINGQRINQYSEVVLAGSHININ
                     GVPVAQPYEIKCIGDKEKLSNYVDKGSKYLDSIQTNYPMKISIKTEENISMKKMNIPN
                     KLKYIKGD"
     gene            complement(14537..15616)
                     /locus_tag="JAM15_01595"
     CDS             complement(14537..15616)
                     /locus_tag="JAM15_01595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAT6796967.1"
                     /translation="MEGKVKKAFPGGNTSQGSYSFFDYIIPENVKRVFCLKGGPGVGK
                     SSLMKKIYKEFLHRGYDIDLYHCPSDPSSLDGLVIKKLGVVLMDATAPHTMDPKLPGA
                     LDEIINLGDYWNTEELEKNKQEISVYDKDISNSFKRAFKFLKSAEPIFRDIEEKYSDC
                     MDYGKVNLVTEEFIKRLFDGVKSTGNLKREKHLFGSAITPVGCLDYTENILKDVKKVY
                     YLDGEIGTGKTTLLNKVYKKAIEKGLNVEVYHYPLIPEKIETVLLTDLDIGITISTTF
                     KEEDTIDLNQFLNREKLLKYEEDIKFDEKVLDDLICWAVLNLKRAKSKHDIIESYYSP
                     NMRFDEVGKLRDKLIKRILKYEENL"
     regulatory      15904..16019
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            16194..17564
                     /locus_tag="JAM15_01600"
     CDS             16194..17564
                     /locus_tag="JAM15_01600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAT6796968.1"
                     /translation="MKQKWIVLIIICIGVFMSTLDGSILNIANPTIAADFKINMSQIQ
                     WVVTAYMLVVTATMLFFGKLGDKVGSNRLYTLGFFIFTIGSFLCSMSNNLSTLISSRI
                     FQAVGASILMATGLGIVSNAFPANEKGKAIGITGAVVGIGNMSGPVIGGIILEHFGWP
                     SIFIINIPIGIIAVFLGIKFLPKPVLDEQNKSFDISGLLLFASCTTLILLAMNEKGNT
                     RLYLGITALIIFLLLALREVKFEQSFIDLPLFKNRNFTVGNIIGVACYFPQMAVSFLL
                     PFYLEQLKNLSPMMAGYVMTVHPLIMVLIAPIAGSLSDKHGAKNILTASFSFMTISLV
                     GMALLKADSPLYLLIVCLVIFGLGLGAFSSPNNSSILADVPPQKQGYGGSFLATIRNL
                     SFALGTAFFSSFFAQSLTYNQKFKSHTSAYVIASNQSYWIAASVCFIGLILTVFFMRK
                     TDKSIS"
     gene            complement(17829..18440)
                     /locus_tag="JAM15_01605"
     CDS             complement(17829..18440)
                     /locus_tag="JAM15_01605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HAT6796969.1"
                     /translation="MKIRSSEITMSAVNKSQYPAEGIPEIALAGRSNVGKSSIINTLL
                     NRRNFARTSQTPGKTRTINFYLINNEFYFVDLPGYGYAKIAKSEKEKWGGIMERYLES
                     RQELCSIFLLVDIRHEPTADDKLMYEWIKHFGYNCVVIATKADKISRGQYQKHISIIR
                     KKLQMESSEKVIPVSSLKKTGVEELWEEIVNQYNQHGYEITVD"
     gene            complement(18430..20793)
                     /gene="lon"
                     /locus_tag="JAM15_01610"
     CDS             complement(18430..20793)
                     /gene="lon"
                     /locus_tag="JAM15_01610"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HAT6796970.1"
                     /translation="MEQNYTKIDHELPLIPLRGLAIFPYMILNFDIGREISLKALDQA
                     MMDEELIFLTSQKEAEVDEPGEEDFYHVGTICKVKQMIKLPGDTVRVLVEGVSRGRVK
                     KIEQEDGYFRAVIEEIVFNSDNLDSETEVEIEAFVRNVFDAFEEYINIGNRVSPEILI
                     SLADIEDVDRFIDTIAANIYLKSSQKQEILEEFDIRKRLELIYSILLEEIDILKIEKK
                     ITLRVKKQMNKVQKEYYLREQLKAIQKELGEEEDINSEADEYREKLKKIKAPKTTKEK
                     IEKEIDKFSKISSMSPDVSVSRNYLDTIFSLPWNKETKDKLDITKAKDILDEDHYGLE
                     KVKERILEYLAIRTLAKSLKGPIICLVGPPGTGKTSIVKSIARALNRKFVRISLGGVR
                     DEAEIRGHRRTYVGSIPGRIINGVKEAQTKNPVFLFDEIDKMAADYKGDPASAMLEVL
                     DPEQNKDFVDHYLEIPFDLSKILFVTTANSLGNIPRPLLDRMEVIEVSGYIEEEKLNI
                     ARKYLLPKQIKEHALKENFIKIDDETLRSIINHYTREAGVRTLERTIGKICRKVAKKY
                     VEDPTLEEVVINKSDLETYLGKDMFKYQLAEVNPQIGLVNGLAWTAVGGVTLEVEVNV
                     LKGKGEIVLTGKLGDVMKESAKTGISYIRSIVDKFDIDPEFYKTNDIHIHIPEGAVPK
                     DGPSAGITMALAVISALTKRPVPGNIAMTGEITLRGRVLAVGGVKEKLLAAHRAGITK
                     VLIPKECEADLDEIPENVKEKMEFVLVEHMDEVLEQALLKSGENNEN"
     gene            20973..21485
                     /locus_tag="JAM15_01615"
     CDS             20973..21485
                     /locus_tag="JAM15_01615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HAT6796971.1"
                     /translation="MLKLFLTFLKIGAFTFGGGYAMVPLIQDELVNKQKLLEQEEFID
                     YLSIAQSYPGVLAVNISVLLGYKLYGIPGVLICTLGSALPSFCIVLVLSYLYFKNSSS
                     KILDGFFKGVAPVVIALILYSFTSMFKKLPKSKTNILLLIIAVLSVGVFNISPIYLII
                     GGGVYSLCQK"
     gene            21473..22000
                     /locus_tag="JAM15_01620"
     CDS             21473..22000
                     /locus_tag="JAM15_01620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HAT6796972.1"
                     /translation="MSEIILLFLIFLKIGAFSFGGGYAMLPFIQQEFISKYHFITNQE
                     FLDLLAISQSTPGPVAINSATFVGFKTAGFFGSLAATIGVTIFALIGLTIISKLFSKF
                     KNNKKVENLLTVLRPITLGFILSAAFSSAKEVNWDLYGIIAFIASFYLLYKGKIGSIA
                     IVFVFGILGILLTFL"
     gene            complement(22071..23321)
                     /gene="clpX"
                     /locus_tag="JAM15_01625"
     CDS             complement(22071..23321)
                     /gene="clpX"
                     /locus_tag="JAM15_01625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018591840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HAT6796973.1"
                     /translation="MSKYEEKRQLKCSFCGKNQDQVRRLIAGPNVYICDECVELCDEI
                     IQEEIEDTIDEDTTSLPKPKEMMEILNDYVIGQEKAKKALSVAVYNHYKRIYSKKSSS
                     KDIEIQKSNILLLGPTGSGKTLLAQTLARTLNVPFAMADATSLTEAGYVGEDVENILL
                     KLIQAADFDIEKAERGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVAN
                     VPPQGGRKHPHQEFLKIDTTNVLFILGGAFDGLEKIIQKRGGDKTLGFGAKIESKKEL
                     DLGKLYEKVLPEDLLKYGIIPEFIGRIPVLATLELLDEDALMQILQEPKNALVKQYKK
                     LLELDDVELEFEEGALRAIAKKAIERNTGARGLRSIVESVMMETMFEVPSRDNIKKVI
                     VTEKSVNEDSVNPIIVLKDQEESA"
     gene            complement(23340..23924)
                     /gene="clpP"
                     /locus_tag="JAM15_01630"
     CDS             complement(23340..23924)
                     /gene="clpP"
                     /locus_tag="JAM15_01630"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HAT6796974.1"
                     /translation="MALVPVVVEQTGRGERSYDIFSRLLKDRIIFLGDQVNDATAGLI
                     VAQLLFLEAEDPDKDIHLYINSPGGSITSGMAIYDTMQYIKPDVSTICIGMAASMGAF
                     LLAAGAKGKRLALPNSEIMIHQPLGGAQGQATDIEIHAKRILKIKETLNEILSERTGQ
                     PLEKIKMDTERDNFMSALEAKEYGLIDEVFTKRP"
     gene            complement(24073..25359)
                     /locus_tag="JAM15_01635"
     CDS             complement(24073..25359)
                     /locus_tag="JAM15_01635"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HAT6796975.1"
                     /translation="MKAELIKKEGNKVTLKITVDNNKFEAAVNKAYNKSRNKYNIPGF
                     RKGKAPRIVIETQYGKGIFYNDAIEILFPEVYPEAIKELDIDPIDNPDLDIEEISKDN
                     GLVMVLNVEVKPEFELGNYKGIEIAKVENTVSDENVDAKLQEMVEKNARLVSVEDKAL
                     EDGDTAIIDFEGFENGVAFDGGKGENYNLVIGSNTFIPGFEEQLVGKKAGEEVEVNVT
                     FPEEYHSQDLAGKPVVFNVKINDVKVKELSALDDEFAKDTSEFDSLDELKADVRAKLE
                     EEAKNRADAETRNSVVEKVAENTEIEIPEVMIQHQIDNMLNELNYQLQYQGFGLQQLL
                     EMTGRTMEELREERKEDAKKLVKSSLVLEAITKAEGIEATEEEFKAELEKMASAYNME
                     VEKIEASLRDADKEDIKGQIKIRKTIDLLVDNATIA"
     gene            complement(25553..26023)
                     /locus_tag="JAM15_01640"
     CDS             complement(25553..26023)
                     /locus_tag="JAM15_01640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HAT6796976.1"
                     /translation="MKIGIVSDTHMMIKNMEKTIPYLKECDLIIHAGDNFTDSRYIHS
                     MTNVGIIAVKGNCDFDAVEEEVVFEVANKTIFLCHGDKYGVKYGTNMLEKKATEVDAD
                     IVIFGHTHTPFREIKDGVLYINPGSTSLPRGVSYKSFVIMDIEEDDIKIEEIRI"
     gene            complement(26023..27372)
                     /gene="rph"
                     /locus_tag="JAM15_01645"
     CDS             complement(26023..27372)
                     /gene="rph"
                     /locus_tag="JAM15_01645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HAT6796977.1"
                     /translation="MTRSYDRSNEQIRPVKITRDYTKYAEGSVLIEMGETKVICTASV
                     EEKVPPFLRNSGTGWINAEYSMLPRATQQRKIRDASRGKIDGRTQEIQRLIGRAIRSV
                     VDLNKLGERTIWVDCDVIQADGGTRTASITGAFVAVAEAIYKLYKAKTIKEMPITNFV
                     SAISVGIVNGIHMLDLCYEEDSKAQVDMNIIMTDKCEFVEVQGTGEEKPFSRADLNLL
                     LELGEKGNKELIRLQREALGEIADEILGMDYGNEVVIATNNAHKLEEIGEILKDFEYK
                     VYSLKDVDLAGIEIVEDGKTFEHNALIKARAIAKKTKLIAISDDSGLEVDALGKKPGV
                     YSARYAGEHATDEENRKKLLKAMQNVPMSKRNARFVSAIAVVFPDGKEFVVRGICEGM
                     IGFEEKGKNGFGYDSLFIVKGYDKTFGEIPSVIKNSISHRANALKLMKQEFIKRIVK"
     gene            complement(27532..29556)
                     /gene="ligA"
                     /locus_tag="JAM15_01650"
     CDS             complement(27532..29556)
                     /gene="ligA"
                     /locus_tag="JAM15_01650"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HAT6796978.1"
                     /translation="MSVKDEINKLIETINYHNERYYNQDSPEISDYEYDKLMKELISL
                     EEEHPELKRIDSPTNRVGGKPLDKFNQIVHKTPMLSLSNAFSEQDLRDFDKRVQEYVG
                     ENVEYVVEFKIDGLSVGLTYNNGEFEKGATRGDGVVGEDISQNLMTVKSIPLKINDKK
                     ELIVRGEVYISKDNFRKVNEQQEEQEQPLFANPRNLAAGSLRQLDPKLTAKRPLDIFV
                     FNMENIEEYDLESHSESLEYLEKLGFSVSQSYKVCKSIDEVIEHIEYWTDNRGNLDYE
                     IDGMVIKVNNIKQRDEMGYTAKSPRWAIAYKFPAEKKKTKIVDIIVEVGRTGTITPSA
                     ILEPVRLAGTTVSRATLHNEDYIREKDIKINDTVLVQKAGDIIPQVLEVIKEERTGDE
                     IDFKMPEKCPVCSEPTIRLEGEAAVKCINMSCPAQIRRGIIHFVSRDAMNIDGLGESI
                     ITLLLNEKIIQDVSDLYYIKKEDVVDLERMGEKSADNLINSIEKSKENDLWRLINGLG
                     IKFIGVKAAKILAYNFKDLDEVISATSEQLEELEEFGSIMANSVVEFFKEDKNMNVIN
                     KLKNVGVNTKSLDNTGEKVEKIFEGMKIVLTGTLTTLKRNDAKDMIEKRGGKATSSVS
                     KSTTFVLAGEEAGSKLTKANDLGIKVIDEERFLELLKLSSKDEVKAVLES"
     gene            complement(29742..30680)
                     /locus_tag="JAM15_01655"
     CDS             complement(29742..30680)
                     /locus_tag="JAM15_01655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAT6796979.1"
                     /translation="MKVLFTINYGKEKFDKIRELGYDVIHYSEDSIENNEDVNTADVL
                     VTYNPFERLDIFKMKNLQYIQTTSVGIDQLPKEEVLKRNIKIANNRGGYSVPIGESIV
                     LYILEIYKNSAKFFKQQQNKEWKMDFSVSELYGQRVGFLGTGTISSEAAKRLKAFGVE
                     IWGVNTDGSSKKYFDKCFATEDMNIVFEECDIVVVAMPSTKSTDGIVNKDMFKLMKDG
                     SVFINVGRGNTVNQKDLEECVEKFRGVALDVFESEPLNKDNKLWECENVIVTPHNSWV
                     SDKNKERTFNMVYNNLKHYIMENKPVDNVVDISRGY"
     gene            complement(30782..31204)
                     /locus_tag="JAM15_01660"
     CDS             complement(30782..31204)
                     /locus_tag="JAM15_01660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3783 domain-containing protein"
                     /protein_id="HAT6796980.1"
                     /translation="MSFEKINNNNLDKIHNRKCIMLVNFNKKELSLIKNVSNFAGIRD
                     HIILSERNGENIIRDILDGNISSECENGIKSKSVIFNNTPSTQVNAFLEGLKKVRINR
                     PFTAMVTETSIDWTLNNLIENLVQERNAMSLGKTIEHK"
     gene            31392..32675
                     /locus_tag="JAM15_01665"
     CDS             31392..32675
                     /locus_tag="JAM15_01665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAT6796981.1"
                     /translation="MNTLLNNKFSIKNFSNAWVIVLGCMLIQAVPFSIVASIQPQFIS
                     YVVEGEGFSLASFSLIFTIGTIASAIASPFIGVLFSKVNIKILYLLGCIISSIAFATF
                     SICTELWQFYTVSCIVQIGATIISAIGIPVLISAWFDEESKGKALGFAFAGGSIGSIF
                     LQPLAVRLLATQGYSHSYLIFGIIALIVGIPVILFILRMPKDINEKVKSKGKKEKASD
                     TISPSVWGYTLKEAKKIKYFWIMTIGFIFVGIYVSSLSVQYPTYLRNYLNPILIGTVG
                     STFALFALIGNLFGGLLFDKFGQTKPLIISFVLVLIATLSLLLVDKSSTFAFVFAILK
                     GLSVFAYMIGPAYLTGSFFGQKEFGSIYGIVQLIFAVGFALGSTLFGLLVDNFGYRFS
                     WSIIILSVIIAYTLLIITSIGMKKLNKERLDKLMQ"
     gene            complement(32753..33268)
                     /locus_tag="JAM15_01670"
     CDS             complement(32753..33268)
                     /locus_tag="JAM15_01670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HAT6796982.1"
                     /translation="MNYFVIADPDKCIGCRTCMIGCVVAHSDEDIFYQNPDEINFNPK
                     LSVIKTKEVSAPIQCRHCEDAPCAKACPNGGIVRVGNTIKINEENCIGCKTCMLACPI
                     GAIDIVTLKDVDEGKLCFRERMTANKCDFCIESPEGPACVNVCPTKAFTIVKDEDIDS
                     KVKNKRKLAIL"
     gene            complement(33268..34644)
                     /locus_tag="JAM15_01675"
     CDS             complement(33268..34644)
                     /locus_tag="JAM15_01675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HAT6796983.1"
                     /translation="MIINIDKDLCTGCRECSKVCPVNAIEGEDGKPQEINLDRCVMCG
                     QCVQTCKSYASVIDEGFEFLQEKKQEREIPESINEPIFAAYNVCDIDKVKKALSDPNV
                     FTMVQCAPAVRVALGEDFGYYLGYLGAGKMAAALRALNFDRVYDTNFAADLTIMEEGS
                     ELIKRVTEGGTLPMFTSCCPAWVKFMEKNYPKLTNHLSSCKSPQQMGGAIFKTYGAEI
                     NNVDASKIFSVSIMPCTCKKYECDREEMDSSGYRDVDVVLTTRELAYLIKDMGIDFKN
                     LREEKFDSPLGSYSGAGTIFGVTGGVMEAAIRTGYEIITGESIPDVEVKQVRGENGFR
                     KSTIKIGDLDLRVGVVSGLKNVIPVLEDLEKGKLDVDFIEVMTCPVGCVSGGGQPKIL
                     LEEYKELAYENRTKATYVHDEHLAIRKSHENPDIKKLYDEYLVEPLGEKSHHLLHTTY
                     CIGKEVAK"
     gene            complement(34669..35220)
                     /locus_tag="JAM15_01680"
     CDS             complement(34669..35220)
                     /locus_tag="JAM15_01680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HAT6796984.1"
                     /translation="MKNKIGSFVIADPNKCTGCRACEVACFTMHNQHNNVGYTVGTVD
                     IPVIPRLYLVKGDNFCMPIQCRHCEDAPCLNSCPQKAIVKENNIMSVNEEKCIGCKTC
                     LLACPFGAIDLLPQYEDGKEVEQVILDENKKIAYKCDLCKDNEKIACISACPQEALKL
                     VTPIDDKKAKNRQAALSLLLTNK"
     gene            complement(35278..35493)
                     /locus_tag="JAM15_01685"
     CDS             complement(35278..35493)
                     /locus_tag="JAM15_01685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796985.1"
                     /translation="MQIHRELSKSENKYMCTKKEEQKCSKCEICGVLIDDTDKVYNNT
                     YNLCKKCKRNISTEKIVKYINIYDESK"
     gene            complement(35462..36295)
                     /gene="fdhD"
                     /locus_tag="JAM15_01690"
     CDS             complement(35462..36295)
                     /gene="fdhD"
                     /locus_tag="JAM15_01690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HAT6796986.1"
                     /translation="MNNIYSKTKLQENSKDKVFENSYSLVDYKYLNSFNVEVSKINEH
                     EVSIDNEEIIAEYPLSFILNDKYVNTFLCTPYNLEELIVGFLKTKGYIENKKSLLKFE
                     INESERFAKVTIQEKQKNQDEQIIFLNSLDYITCASVKSNIKINYDTIYSIMDRNLNS
                     SELFKNTGGVHSVSVFNFDKKIVTCEDVARHNAMDKAIGFCVLNDITLKDKIVAVSGR
                     ISLEMILKAAMTQIPIVVSKSAPTNLSIELSKKLNITLIGFVRGRRMNIYANPQRVIK
                     K"
     gene            complement(36344..38488)
                     /gene="fdhF"
                     /locus_tag="JAM15_01695"
     CDS             complement(36344..38488)
                     /gene="fdhF"
                     /locus_tag="JAM15_01695"
                     /EC_number="1.17.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(38072..38074),aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase subunit alpha"
                     /protein_id="HAT6796987.1"
                     /translation="MEKKILTVCPYCGAGCQLYLVVKDNKILRAEPANGRTNQESLCL
                     KGRYGWDFLNDPKILTPRLKKPMIRKQGVLEEVEWDEAINYTASRLNEIKEKYGPDSI
                     MGTGSARGPGNEANYIMQKFMRATIGTNNVDHCARVUHAPSVAGLAYSLGSGAMSNSI
                     PEIENADVLFIFGYNGADSHPIVANRIVKAKKNGAKLIVTDPRVTESARIADIHLPIK
                     GGTNMVLVNAFGNVLIEEGLYNKEFVQNHTQGFDEYKEIVKPYTAKYAEKITGIPEEL
                     IRKAMREYAKGKKAMILYGMGVCQFGQAVDVVKGLASIALLTGNFGRESVGIGPVRGQ
                     NNVQGACDMGALPNVYPGYQNVTDDKIREKFEKAWGVKLSPNNGYSLTQVPDLVLKEK
                     KLKAYYIFGEDPVQSDPDASEVREALDELEFVIVQDIFMNKTALHADVILPATSWGEH
                     EGVYTCADRGFQLMRKAIEPQGDVKPDWQIISEISTAMGYPMNYKNTKEIWDELRQLC
                     PSFLGATYEKIETQGCVQWPCKSESMEDKGTMYLYEGQKFSTPNGKGNLFAAEWRPPM
                     EVEDDEYPFSLCTVREVGHYSVRTMTGNCRTLSSLEDEPGRVQINSNDAEKLGIEDDE
                     LVRISSRRGSVITRATVTDRVKEGATYMTYQWWVGACNELTIANLDPISKTPEYKYCA
                     VKLEKLEDQELAEKCVREEYQSLKDKMTATNI"
     gene            complement(38739..39797)
                     /locus_tag="JAM15_01700"
     CDS             complement(38739..39797)
                     /locus_tag="JAM15_01700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HAT6796988.1"
                     /translation="MDRLKNIRKSLLQYTFLFLLIGITIYLVFKTLDIKMLSNVMVMV
                     DKKFLFIGALAIMCHIMLEGVVMKIIIESTHKVNIRFIGFKLAIMGFYYNLITPFASG
                     SQPVQIYVLKKCKMPLSKASAVVTNKSIIFQIVVTFYCTILVLMNFAMLEKQMKMIMP
                     LVFLGIAINSFVLIMIILVILNPKKIKYFMRITIKHLSKIKFLKFLDNKIESIESFID
                     DYSKAINFFAKNKKVLISTIIVTFIQLSAYFSVSFWIYKAFNLQGYSYIYILTLQAFL
                     YMAISPIPTPGNVGANELAFFTIFKSVFPQPLMGYAVFLYGGFMYYLILIGSGIFTVI
                     THYRMKNRIGRNIVLSEN"
     gene            complement(40008..40667)
                     /gene="cprR"
                     /locus_tag="JAM15_01705"
     CDS             complement(40008..40667)
                     /gene="cprR"
                     /locus_tag="JAM15_01705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CprR"
                     /protein_id="HAT6796989.1"
                     /translation="MSKILVVDDELDMLKLIENVLKRDGHEVKVISDVEKAMNMDFNY
                     FNLIILDVMMPKMDGFEVCKTIRNKVDCPILFLTAKNMESDIMYGLGIGADDYITKPF
                     GVGELRARITAHLRRESREKKNLLTISNVQFNFLGKEVSIDGKKINFTKSEYLICEFL
                     AKNKGQVFSKERIYESVYGFDGESDISTITEHIKNIRSKLKQYDIYTIETVWGIGYKW
                     V"
     gene            40978..41607
                     /locus_tag="JAM15_01710"
     CDS             40978..41607
                     /locus_tag="JAM15_01710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3786 domain-containing protein"
                     /protein_id="HAT6796990.1"
                     /translation="MDENITKNNYNVPFDYVRKKLKELDPHTISNLSNIPFNNDLNRF
                     TLNFFDRQYIIDYPSGEVWNSNGSLCNNFELKILIVRYLINAKGIPRTNKYVTFKEIP
                     GGNVYYPNFLNRTLYRLSEVFTSQIDKYKLVMEKIGAEKVNMGDLAYRFTYMGNTSMI
                     FILWFGDDEFPPNSNILFDSNIVYYFNAEDLAVVPDTAINAILNKINQL"
     gene            41675..42508
                     /locus_tag="JAM15_01715"
     CDS             41675..42508
                     /locus_tag="JAM15_01715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prenyltransferase"
                     /protein_id="HAT6796991.1"
                     /translation="MNVENQSLSDIEIILSHRYDNGADYWTTPDKRLIKGSPFSTLDS
                     VLYLLELGVNPDDTLLKECADLIFSTWREDGRFKLYPNGGIYPCHTANAANVLCHMGY
                     ASDIRMQKTFQHFLDTQYTDGGWRCNKFSFGRGPETEYSNPLPTLNILNAFRFSNYLN
                     KESKLDKAVDFLLDHWTIKKPLGPCHYGIGTLFMQVEYPFRNYNLFLYVYVLSFYNRA
                     KKDKRFLEALKILESKMIGNKIVVERVVPKLSKLSFCKKGESSEIATTHYYEILKNLE
                     K"
     gene            complement(42604..43392)
                     /locus_tag="JAM15_01720"
     CDS             complement(42604..43392)
                     /locus_tag="JAM15_01720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796992.1"
                     /translation="MCILELIKFELKKIELKHVLIFVIISILCIFITGILDYNELIFY
                     NDVPIMDTYSIAGWLGIIKISDVFIPIMSAITIIYVFSKDYLGNINEILTLYNKKKYN
                     QFIVFRWCVILAIYTVLLLISITIVYTFTSVKGFNIDKIDFVYSVKPIDVFLKTFPTL
                     LWYTTFPLMILTLTKNRFTTIAILITYTFADIFFILHMYPFVSMINVNGFYIQKMFYM
                     PNNIDVRFNELKNYFFINRGSLVVISIIIVFYIARKSTVLKKSK"
     gene            complement(43393..44265)
                     /locus_tag="JAM15_01725"
     CDS             complement(43393..44265)
                     /locus_tag="JAM15_01725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAT6796993.1"
                     /translation="MINKLEIRNLNFNYKNKKALDNINLTLTDGVVALLGPNGAGKST
                     LMRLLVTLYETSIGEIELNNIKYSKNNEKIKANVGYIPQDFDMYNNINGQEYLEFVAK
                     MRGVSKNDLKKHIQKVVSKVNLDKFINNKIGTYSGGVKRRLGIAQALIGDSKLIVMDE
                     PTVGLDPEQRNEFRRLLPEISKNSIVLISTHIVEDIQFNCDKLIILNQGKILYDGTIN
                     KFIDMVEVYSVVVSNDEFEYLERNIDIIDYRRVKDGVQVKYIGKNTEKLKDSLRIDTT
                     LQDAYINFLHKELK"
     gene            complement(44280..46058)
                     /locus_tag="JAM15_01730"
     CDS             complement(44280..46058)
                     /locus_tag="JAM15_01730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6796994.1"
                     /translation="MNLLNIVESIVSCIKGLARRGINMSSIKVISDFITKIIRKNILF
                     AITVIIINYHLIQRWTHISNRGISFNDYLSLSVYTCMTISILTMLNVIFYMRKSYDTV
                     KILCRNNFDYFLGISVAVTRNNFIFCCIPIIYAIAYSSLIRTLSIVTIKSTIFILVFE
                     WFLPLTILSIVISFISVIINNLILKITLSSVFLYLTSTKMLDRVIDIKEPFFKALFKS
                     LNIFEDQSYAYYSDFVGKVNNSAYVIDKIIPTLFAITLIIVAYLILNDIRKKQIKSLI
                     VIVVYSILFIGLNYISIDMSTYRDEERSYGEYLKKSNISDIKIKSHDMKIDFKSKSNI
                     KDRIVLLNTSNEELTNINMILDEIFDIKYIKVNSENIKFNKKKDLIEVNLKESLEPND
                     EVTLDIEYEGYINVLTSWNQNKYIATKDDIMLPPGSLAWYPKVNQSSCMAYKINLSSK
                     NNVYSNLPLLNKTSNFLKKDYIFEGKSNDIAIYAGEFKEEVKDDIKIIYPSDSNVNMD
                     IEEKIKFLIETRNEILGDSKASVDAKKYVDEVDNVMESIKRKKINMILVADLPSNEFL
                     YEDSKGEKISITIYHWLSGNILIIDK"
     gene            complement(46136..46717)
                     /locus_tag="JAM15_01735"
     CDS             complement(46136..46717)
                     /locus_tag="JAM15_01735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HAT6796995.1"
                     /translation="MFKRLSYKFANILVNNEIVESEDFEIYRYGFETLIYFIVNISVA
                     LFIGIIFDRFIHTVIFLSCYCTLRQFTGGYHARNYKECTLTFAVIYLITIFSANNIDI
                     NKYKYLLVLLMIISILTIYKLAPLEHRNKPLSESEKKHYRKTVQKILFVIICLIILCK
                     ILNIFQQYVIYAIISIYWIAILIYVGMKVNSDQ"
     gene            complement(46776..46916)
                     /locus_tag="JAM15_01740"
     CDS             complement(46776..46916)
                     /locus_tag="JAM15_01740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HAT6796996.1"
                     /translation="MKKIALNLLKNISALSFGIAVLSANSASSWVAHQAKEPQALQKL
                     KK"
     gene            complement(46928..48244)
                     /locus_tag="JAM15_01745"
     CDS             complement(46928..48244)
                     /locus_tag="JAM15_01745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAT6796997.1"
                     /translation="MLTNLSIGFWNIINLVSGTIDWIIFFLVIHLVGKRKISNIRYIF
                     TTIIIFIFMAYINVVKVFPNIKILLCMVIGISFYITSYEDKIYKSIIVSLLFWLGLMI
                     AEGSAVGLVVFINKLNNINITQHENLFRIQAIIMSKVFLFIGFILFKYFKLSLDFKPK
                     DMILIGIPILSNIVSLLLIFEYNLRVNTITTENLFIFIFVILLILSSSIILLIVIGKI
                     VQDDKLNLEYELINERIKTNYRNYENINEVHDRLKYVYHDLKNHMICIKNYDTKEEII
                     SYIDNLEFQISEFEHFKNTGNKTLDLILAEKISICKKYDIQIEDNINISKLNFIENND
                     ICSIFANSLDNAIEACMDINNELEKRIEVKATYINKFAIIKFINTKVNDIKLIDKRIQ
                     TSKDDDKIHGIGLASIKYIVNKYGGETIVNYSDNEFILKIMIPIKS"
     gene            complement(48238..48948)
                     /locus_tag="JAM15_01750"
     CDS             complement(48238..48948)
                     /locus_tag="JAM15_01750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6796998.1"
                     /translation="MISIGICDDELHYRIKIKDILSEILSSYPINYNIYEFSSGEELL
                     NNYPKDLDILIMDIQMKTINGMDTARKIREFDHKLEIIFVTSFVEFMQEGYEVKAYRY
                     ILKPINKEKISKSVLPCINEMMKKRNNYLTINVKNYVDRIKIDSITYIETDRPNILIY
                     THDDMYITKMSISKIEKILNEYGFFRCHNSYIVNLKLVESMSGSTVIVDGKSIPISKY
                     RVKGLKLAITNILGDIVC"
     gene            complement(49386..49961)
                     /locus_tag="JAM15_01755"
     CDS             complement(49386..49961)
                     /locus_tag="JAM15_01755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1062 domain-containing protein"
                     /protein_id="HAT6796999.1"
                     /translation="MKKITWEVEYISQLPVIRYCKKCGKKTEYICSGLFRVNAQHKYL
                     DIWLIYKCSNCDSTWNSTIYSRVNPKSLNPEILEQFHTNDYNLVKQYAMNTELLHRNG
                     AEVGIPEYKIVGQEININDLTQVHIISKYPCQLKVSTLLREKLGLSRKVFDEMLDCGI
                     IRSNSGVDLKKGKLNYEIMLDIGKEKQKSSN"
     gene            complement(50254..50532)
                     /locus_tag="JAM15_01760"
     CDS             complement(50254..50532)
                     /locus_tag="JAM15_01760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797000.1"
                     /translation="MSYKKAIHILPEELLELIQEYVDGEYIYIPRKSNNKKEWGSSTS
                     TREDLSIRNMQIYEDYQIGYDLKYLSEKYYLSLKSIQRIVLQEKRKDS"
     gene            complement(50841..51602)
                     /locus_tag="JAM15_01765"
     CDS             complement(50841..51602)
                     /locus_tag="JAM15_01765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase"
                     /protein_id="HAT6797001.1"
                     /translation="MKNKIETSMNNFVKNYHKSNNITTKWQELLFAYASAEDDMFQKL
                     KSVVGTSHAMPKDFLENGKTIITYFIPFDESVNNSNIGGFECSEIWARAYIETNMLIS
                     NLNDFLCEELEKMGANSYAIPGSYNFDSEKLVSDWSQRHVAFIAGLGTFGLNNMLITE
                     KGCCGRIGSIITSLELEPTKRPENEYCLYKHNNSCKKCINKCVKEALKEDGFNRNKCY
                     EMCMINEKKYTYIGGCDICGKCIVGVPCSVINPSR"
     gene            complement(51771..53837)
                     /gene="bclA3"
                     /locus_tag="JAM15_01770"
     CDS             complement(51771..53837)
                     /gene="bclA3"
                     /locus_tag="JAM15_01770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA3"
                     /protein_id="HAT6797002.1"
                     /translation="MLLIMSRNKYFGPFDDNDYNNGYDKYDDCNNGRDDYNSCDCHHC
                     CPPSCVGPTGPMGPRGRTGPTGPTGPTGPGVGATGPTGPTGPTGPTGNTGNTGATGLR
                     GPTGATGGTGPTGATGAIGFGVTGPTGPTGATGATGADGVTGPTGPTGATGADGITGP
                     TGATGATGFGVTGPTGPTGATGVGVTGATGLIGPTGATGTPGATGPTGAIGATGIGIT
                     GPTGATGATGADGATGATGADGATGVTGPTGPTGATGADGVTGPTGATGATGIGITGP
                     TGATGATGIGITGATGLIGPTGATGATGATGPTGVTGATGAAGLIGPTGATGVTGADG
                     ATGATGATGATGPTGADGLVGPTGATGATGADGLVGPTGPTGATGVGITGATGATGAT
                     GPTGADGLVGPTGATGATGADGVAGPTGATGATGNTGADGATGPTGATGPTGADGLVG
                     PTGATGATGLAGATGATGPIGATGPTGADGATGATGATGPTGADGLVGPTGATGATGA
                     TGPTGPTGASAIIPFASGIPLSLTTIAGGLVGTPGFVGFGSSAPGLSIVGGVIDLTNA
                     AGTLTNFAFSMPRDGTITSISAYFSTTAALSLVGSTITITATLYQSTAPNNSFTAVPG
                     ATVTLAPPLTGILSVGSISSGIVTGLNIAATAETRFLLVFTATASGLSLVNTVAGYAS
                     AGIAIN"
     gene            complement(53904..54980)
                     /locus_tag="JAM15_01775"
     CDS             complement(53904..54980)
                     /locus_tag="JAM15_01775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAT6797003.1"
                     /translation="MITISLCMIVKNEEEVIGRCLECVKDIVDEIIIVDTGSTDSTKE
                     IVSKYTDMVYDFEWIDDFSAARNFSFSKASKDYTMWLDADDIILEADREKLLKIKESL
                     DTSIDIVMAKYNVSFDENGNPTLSYYRERLFKRSSNHKWVDPIHEVVPLFGEVFYSDI
                     AISHKKLHRQDPLRNLRIFEKMISEGKTLEPRHQFYYSRELYYNARYKEAIEGFTKFL
                     DSSRGWIEDCISACRDLATCYYLINDEKSALYSLFRSFEFDEPRAEICCDIGKHMFDR
                     QKYKEAIFWYKVALTRDKNDTNGGFKSNDCYGYIPSIQLSVCYDRLGESDKAIYYHEK
                     TKEIKPNDSAVLHNENYFSKFKNS"
     gene            complement(55292..55876)
                     /gene="clpP"
                     /locus_tag="JAM15_01780"
     CDS             complement(55292..55876)
                     /gene="clpP"
                     /locus_tag="JAM15_01780"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HAT6797004.1"
                     /translation="MSLVPHVIEQTGQGERSYDIYSKLLKDRIIFIGEEINDAIASLV
                     VAQLLFLESEDPDSDIIIYINSPGGSATSGFAIYDTMNYVRCDVSTICIGMAASMSAF
                     LLAGGTHGKRCALPNSEIMIHQPMGGAKGQATDVKIAVDNILKIKERLDKILSENTGK
                     SIEDIRRDTDRDNFMTALEAKEYGLIDYIMNRNE"
     gene            complement(55873..56355)
                     /locus_tag="JAM15_01785"
     CDS             complement(55873..56355)
                     /locus_tag="JAM15_01785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6797005.1"
                     /translation="MKTNTDVIMEIIDYIEENLTENLNLDKIAYIANYSKYHLHRMFT
                     NVVGCTIHQYIQRRRLTEAARQLIFTDKYIIDIAIKVGYSTHQSFTLAFRNLYKESPQ
                     VYRNKDEFYPIQQRFVLNLNHQIQSEKCISYANMNYKQRRDEINSYLNFNINCEVKVA
                     "
     gene            complement(56554..57969)
                     /locus_tag="JAM15_01790"
     CDS             complement(56554..57969)
                     /locus_tag="JAM15_01790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAT6797006.1"
                     /translation="MWITINRNSNISLSRQIYCEIKDMILDGSLKFEQKLPSSRTLSK
                     ELSVSRNTVLDAYNQLIAEGYLETRNGYGTIVAKGISGHKVDFKLNDTFRDEKDLHTN
                     KQKNYIDFRSGVPELKLFPRKELSKLYKQILYDLSDSDFRYGSTAGVWVLRVEISKYL
                     FRTRGIRCNPKNIMIVSGSTQGLSLISQLLYKSNKKVAVEDPIHKGLLKVISSIGYSV
                     VGIKVDDKGMNTNLIKSIKGISFVYTTPSHQYPLGGILPIQRRLELIKCATENDYYII
                     EDDYDSEFRYEGQPISSLYELSPNKVIYIGSFSKILSPAIRVGFMLLPDNILESYKTL
                     KMYSDVHTETILQYVLAEFIGNGGLEKYIFRMKKLYNRKHKYLIKVLNTEFKNEFKIK
                     GEAAGLHIVAHFYNVKFTESLIHKIFEAGIKVYPIQQYAIENILEYDHEIILGYAHLS
                     FDEIEKGVKILSKIIHMNQGT"
     gene            58084..58752
                     /locus_tag="JAM15_01795"
     CDS             58084..58752
                     /locus_tag="JAM15_01795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797007.1"
                     /translation="MLEISHKVKEIYPNIKFGVMVINITHSKPNKENFLVLKNSTIKN
                     IIEQHPEYNRKEKIKTEPVSSYIKYYKKFKKTYPVLLQLESILLKSKGIPDVGVTIES
                     MFLAELKNLLLTAGHDLDKMELPLKIELANGSEHFYGIGGKEHILTKDDLFLSDNIGI
                     LSSILNGPDNRTAITKDTKNIMYFVYGPDKISEKQIQDHLNDIKHYISSAFPDLKVNS
                     IDIF"
     gene            complement(58928..59446)
                     /locus_tag="JAM15_01800"
     CDS             complement(58928..59446)
                     /locus_tag="JAM15_01800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010964793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="HAT6797008.1"
                     /translation="MNFVELTKKRYSCRNYQDRKVEKEKLEKVLDVARIAPTGGNRQP
                     QRLIVIQEKEGINKLSKAANIYDAPLAILVCGDKDKVWTRPFDGKQLTDIDTSIVTDH
                     MMLQATELGLASVWVCYFNPDIIREEFSLPDNLEPINILLMGYESKIPESPERHEKTR
                     VPLSEIVSYETL"
     gene            59598..59921
                     /locus_tag="JAM15_01805"
     CDS             59598..59921
                     /locus_tag="JAM15_01805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6797009.1"
                     /translation="MKKCLDNYSCPIEATLALIGGKYKTLILWHLKDTILRFNELKKL
                     IPKATPKMLTQQLRELESDGLIIRVVYPVVPPKVEYSLSDFGKSIIPILDSMCDWGSD
                     YLESL"
     gene            complement(59926..60510)
                     /locus_tag="JAM15_01810"
     CDS             complement(59926..60510)
                     /locus_tag="JAM15_01810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HAT6797010.1"
                     /translation="MKVLVFLAKGFETMEFSVFVDVMGWARNDYGHDIDVVTCGFKKQ
                     VMSTFNIQVLVDKTIEEVCVDDYDALAIPGGFEEFGFYDEAYDSSFLNLIREFNSKEK
                     IIASICVAALPVGKSGVLKNRKATTYHLKNGKRQRQLSEFDVNVVNEPIVVDKNIITS
                     YCPETAPHVAFKLLEMLTSKEQMDEVKLAMGFKL"
     gene            complement(60559..61014)
                     /locus_tag="JAM15_01815"
     CDS             complement(60559..61014)
                     /locus_tag="JAM15_01815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HAT6797011.1"
                     /translation="MDEIDLKIINSLKKNSRASTSEISRQINLSVPAVSERIRKIEQS
                     NLIQKYTIQINREKTKYKLLAFIFINTDLSKSMKEFKKTILEYDTVLECHHISGEYDY
                     LIKVLAEDTSNLEEFISVTLKEIGGIQKANTTIVLSTIKEEFNTIKDIF"
     gene            61897..63435
                     /locus_tag="JAM15_01820"
     CDS             61897..63435
                     /locus_tag="JAM15_01820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAT6797012.1"
                     /translation="MSLLKVTNLSQCFMDKSLYEKANFDLFKGEHIGVVGQNGAGKST
                     LIKILLGEVVPDSGEIKWQPNINIGHLDQYAEINRDTTISLYLHTAFEELYKMEKEMN
                     LLYQKSAISENEQYLIKASDYQEQLIANNFYSIDNEINKIANGLGLDSIGMNCVVEEL
                     SGGQRAKVILAKLLLSNHDVLLLDEPTNFLDKEHVEWLSNYLNTFNGAFIVVSHDFDF
                     LEKISTGILDIEFGMIKKYHGKYSEFLKQKSHLREDYIRRYQAQQKKIEKEETFIRKN
                     KAGVNSKIARGRQKQLDKIERIAPPSFTGKPNIQFSEIEISAQNALTITNLEVGYYYS
                     LLPKLNFSVDGGQKIVITGFNGIGKSTLLKTLVKDIPRISGDFQFSEQVKIGYYEQDL
                     KWENPDKTPLQIVADKYPKLNTKEIRRHLARCGVKEEHVSRSVSTLSGGEQSKVKLCC
                     MMLSPCNFLILDEPTNHFDAETKDALQNALKQFRGSIILVSHEEKFYKGWIDKVFNIE
                     KQLV"
     gene            complement(63707..64537)
                     /locus_tag="JAM15_01825"
     CDS             complement(63707..64537)
                     /locus_tag="JAM15_01825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6797013.1"
                     /translation="MSIRDVTISNVKARVVNIKKQDIDTARLEYNKLLWRDFNMDTYF
                     NKKILLVDDEKDIVDLIEEVLINDGFKNIIKAYNGLDAISLCKIACPDVVILDIVLPD
                     IDGIEVCKKIREFSYCSILFLSSKNDDIDKILGLSSGGDDYITKPFSPREIAFRVKAQ
                     LRRQQYQSIVPSDSAVIKIGDITIDIEGNRVYKDRNEIELTGREYHLLSYMAQNVNKI
                     IGKERLYEQVWGVYSSICDNTIMVHIRHIREKIEDNPSNPKILITVKGLGYKLVNRID
                     "
     gene            complement(64875..66254)
                     /locus_tag="JAM15_01830"
     CDS             complement(64875..66254)
                     /locus_tag="JAM15_01830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HAT6797014.1"
                     /translation="MSDVYYSENHEQDNLYEQDNLLAQRFNLFTLLKFAFPTIFMMIF
                     MGLYTIVDTIFVSRFINTNAISAINIVCPIINLIVGIGTMLATGGSAIVARKMGNGDI
                     EGANKAFSLIVLSGVVIGVIITGIGIVFMDYIIIWLGASEVLIKYCRSYLFIILVFAS
                     ANILQVLFQCLFVTAGKPQFGLWLVLGAGCANIILDYVFIVLLQMGISGAALATGVGY
                     LIPTVSGMVFFSKNKGLLKFCIPRLDKRILFEACFNGSSEMVGQLSTAVTTFLFNAMM
                     MKLIGEDGVAAITIIIYSQFLLTSLYIGFSMGVAPIISYNYGSENNTQLNHVFKICIL
                     FISVASLLVFIFSISCSPIIVEIFSQRGSRVYEIARSGFYMFSFSFIFCGYNIFTSSM
                     FTALSNGKVSAILSFLRTFGFITIGLLILPNILNINGIWLAVPSAEILTLFLTIFCIC
                     KYKNRYKYM"
     gene            complement(66539..67330)
                     /locus_tag="JAM15_01835"
     CDS             complement(66539..67330)
                     /locus_tag="JAM15_01835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6797015.1"
                     /translation="MKKNLKIIFMLLKMKLSKMMVFRFDFFGAFFVDSSLFILQLLMF
                     NSIYSYVDSIGGWQQGEMLIFIGTFSLINAINMTIFFFGIYDIPRKIQEGELDYYITK
                     PLDPLFRLTFENINIGSSPLILASILIVLYGISELNSEITLVMIIIYIFMVLLMTLLF
                     YDVCIILRTVSFFVISSSAIMRLEDNLLPMNMKIPGVIYEGVFKVLFYLILPYGIMST
                     IPTQILAGTITINGLIYSILIVFLFTLFMWRFWKLGMRHYKSASS"
     gene            complement(67330..68184)
                     /locus_tag="JAM15_01840"
     CDS             complement(67330..68184)
                     /locus_tag="JAM15_01840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6797016.1"
                     /translation="MSNYNEASSNYSMFYKFKQSIRRYYEVAKINFKVQLIWRFDVVV
                     NMVFTIVKILFAYILWKAIFGENKIVSGFTFNSMLSYYIISSFLAGIDMSKSTSEEIC
                     NRVKLGTFSKYMIIPINVQNYFIAKNFGMTCFYFVFNMISAFVWIFIFKIDFAFTSNP
                     VQILISILMIFLGFIFMMKLHFFIGILSFKFLEISFFRMIIENIVEFITGTMIPLVLL
                     PETIVTVMKVFPFYYTTYLPSMLLIGRNSNEAIQGLIILALWVLFFSVVNKVMYKRMR
                     TLFDGVGI"
     gene            complement(68171..69166)
                     /locus_tag="JAM15_01845"
     CDS             complement(68171..69166)
                     /locus_tag="JAM15_01845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAT6797017.1"
                     /translation="MSIIELNELTKSYRRFEKKAGFMGSVKSLFNRKYTEKTAISSFD
                     LKIEEGEFVGLIGQNGAGKTTLIKMLTGIIAPSSGEISVMGYYPNKLENNFKKQYAVV
                     MGQKSQLFFELTPADTFLLFKELYDISNEEYKKNLDYFIELFEVSDYLNVQVRTLSLG
                     ERMKMELIVALLHNPKILFLDEPTIGLDAIAQKQIRYFLKEVNETKGTTIILTSHYME
                     DIKSLCSRSIVVENSRKIYDGSTEKLFNHFQKYKKITVSFSNETNIVFPKDCKVVEQT
                     NHKTSVIVPKERGNETIKWIFDKYDVKDVMIEEEDIGSIVERIYKKGSDEYYEQL"
     gene            69869..70825
                     /locus_tag="JAM15_01850"
     CDS             69869..70825
                     /locus_tag="JAM15_01850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HAT6797018.1"
                     /translation="MENNTIQKQLRDLSKKIWHIYILNPEEENLKFIISLLDNNLALI
                     GTGKHEFYETLEEFIIGLEKDQTESEQIDFEIIDEWYSCTKVTDEAFIVYGTLWVIEK
                     DYLEKDIYVEMDTRFTMVYRVTDDMIKLIHVHHSIPNFDQMKDEYYPKTITEKAQEAL
                     AMANEFKLKSEKDLMTGLYNRHFFEVHIKEMLKTVSYGYFYIFDLDNFKQVNDIFGHV
                     RGDEILIKFSNILTKVFVNDAIIGRLGGDEFAVFEYSNQSKENVENKSKKVLELCLES
                     NSCSIGISKLENKSDTFQSLYKQSDYALYYSKRNNKGNFSWF"
     gene            complement(71226..71774)
                     /locus_tag="JAM15_01855"
     CDS             complement(71226..71774)
                     /locus_tag="JAM15_01855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797019.1"
                     /translation="MEGLGFYAAALSGSSYQRIGFGKLDPIEVIADGDWISYKQAQDT
                     LTVIRNFLNSFDWRNASEMERANRAAKLVTEAKYVDSKYCNIVYGNLVDKRGVCGSFA
                     SSFHLLTRLMGMDSLSILNPSLNHAWNYIQIDGKWYRSDGSEISAFGGALDFDYRKLK
                     DATREMTTYYDAKALSILGFNQ"
     gene            complement(71876..72574)
                     /locus_tag="JAM15_01860"
     CDS             complement(71876..72574)
                     /locus_tag="JAM15_01860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797020.1"
                     /translation="MKISSQYRSQYSFRHESNINNTRINESMVKKNETVGKDTYLSNI
                     MKQKQELNDRIRDLKYRQEVYIKKINEAIKNLCKSEIRETTNNFSNIEIGIKNSIIED
                     KNKSTMLDENSTYLNINDEKESLITKESNEKIEEEILNDEKLEELEQKKDYKEDSNKK
                     EKVSEDLSLVGKTREELENMLKNFINLTQEEIMKLESRIEKLDKDAEEYKQNSKTNIF
                     DKTDEQKKHINVLI"
     gene            complement(73110..74177)
                     /gene="rsgA"
                     /locus_tag="JAM15_01865"
     CDS             complement(73110..74177)
                     /gene="rsgA"
                     /locus_tag="JAM15_01865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HAT6797021.1"
                     /translation="MNGMKQINLQDYGLNRNFITQSMEYHDLYLARIISQEKNFYQAV
                     CVNGVLFAEVSGKLRFEATIQSDFPTVGDFVMLDRCNNKNGNAIIHHVLHRKSLFVRK
                     AAGKVNEEQVVAANIDIVFLCMSLNKDFNIHRLERYLSLTWESGAIPVVVLTKSDLCD
                     NVHRKLQVVNSIALGVDVVVTSSIEPDGYKQISKYIKSGCTVALLGSSGVGKSSLINC
                     LLGGEFLNTKEIRIDDDKGRHATTRRELFLISGGGIVIDTPGMRELGMWDVSEGLDKS
                     FADIEAYFGKCHFRNCTHTSEPGCAIWEAIAHQELSPKRWESYRRLKTEAVFADNKSE
                     YLAKKEKKFKNISKINKTIRR"
     gene            complement(74174..74575)
                     /locus_tag="JAM15_01870"
     CDS             complement(74174..74575)
                     /locus_tag="JAM15_01870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNHCP domain-containing protein"
                     /protein_id="HAT6797022.1"
                     /translation="MNYKNRKRAYYQENSCMDNFICKNCGCLVVPEGAGTQHRNHCPH
                     CLHSLHVYIIPGDRAADCDANMEPIGVWVRKNGEWAIIHRCTRCGHLSSNRIAADDNS
                     VKLMSIALKPLAQPPFPLERIIEKLEKEETE"
     regulatory      75371..75467
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            76107..76745
                     /locus_tag="JAM15_01875"
     CDS             76107..76745
                     /locus_tag="JAM15_01875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797023.1"
                     /translation="MSNQIKDFDITNDMFQESIPITTKTILEDMPSNDELNHVFSKGC
                     ERKMKKRKIVLITLLLIGVLLLGSILYNLFLVKAANISMLKESWNFDIPIPNKEIEVF
                     DTQDSINGDGQSYFIQGFSEKNFKKVFNLKGGIVVSKDNINEIEKYIDKFKRDSVNIN
                     KSNKNKIEEDFKKYKLEVKKDDKYIYKRNYENYVVLIIKKDEQKLYSLIWNQ"
     gene            complement(77223..78581)
                     /gene="rlmD"
                     /locus_tag="JAM15_01880"
     CDS             complement(77223..78581)
                     /gene="rlmD"
                     /locus_tag="JAM15_01880"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HAT6797024.1"
                     /translation="MLSKNEMYIVDIVDIGQGGVGVGKYNGITVFVEGGLIHDKVKVR
                     INKVKKNYAVGDIVEIIEKSPFRVKRVCSDNLRDCGGCQIQDLDYNKQLEMKTNEVKQ
                     VLSRIGKLEDVEVHDTIGMDNPYRYRNKAQFPIQKNNGIPIIGFYKKKTHDVISTEKC
                     VIQHEINDKIVKIIKTYIRAYKVSIYDEKTHTGLIRHLVTKIGFTTKEVMVVLVANGN
                     KLPYLKELASVLKENIPGFKTLVVNVNQKDTNAILGRENIVIYGDGKINDYIGDLVFE
                     ISPLSFFQVNPVQTKVLYDKALEYANLNDTDTVFDIYCGIGTISLFLAQRAKKVYGIE
                     IIDDAIKDAKINAKLNNIHNAEFYVGKAEEIVPKMYREGKTANVVVVDPPRKGCDEKV
                     LETIVSMNPERIVYVSCNPSTLARDLDYLNVHGFKCVEAQPVDMFPHSTHVETVAKII
                     KQ"
     gene            complement(78756..80516)
                     /gene="pyk"
                     /locus_tag="JAM15_01885"
     CDS             complement(78756..80516)
                     /gene="pyk"
                     /locus_tag="JAM15_01885"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005366042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HAT6797025.1"
                     /translation="MLNNVKKTKIVCTLGPASQSEEVLTQLMQNGLNVCRFNFSHGSH
                     EEHKERIDMAKKVREKLNKPVAILLDTKGPEIRTGNFEDPEVFLEEGQKFTITMKDIM
                     GTKEMCTVSYKGLAEDVKSGDSILIDDGLVGLRVKEINGEDIVCVVENSGIVKNHKGV
                     NVPGVKINLPAITPKDISDIEFGISQGIDYIAASFVRKASDVLAIREVLENNNATDIQ
                     IISKIENQEGVENLDEILKVSDGIMVARGDLGVEIPTEEMPIVQKMMIKKCNELAKPV
                     VTATQMLDSMIRNPRPTRAEVTDVANAIYDGTDAIMLSGETAAGKYPVEAVKMMATIA
                     KRTEETLDYDRLLKENGTNNVTVTDAISHATCTTAVDLNASAIITSTSSGYTARMVSK
                     FRPKSPIIATTNNEKTMNKLALTWGVYPVKSSVAGNTDEVIEKAIEAARQADYIDNGE
                     LVVITAGVPVGVSGTTNLIKVHVISEEIVQGIGVGTQTVEGKVRIIKNGNACVDFNEG
                     DILVSTATDAEMNNYIEKAGAVVTENGGMTSHTAIVGINLDIPVIVSATDITNLVKDG
                     EVVTVDASRGVVYRGSTRVL"
     gene            complement(80568..81527)
                     /locus_tag="JAM15_01890"
     CDS             complement(80568..81527)
                     /locus_tag="JAM15_01890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent 6-phosphofructokinase"
                     /protein_id="HAT6797026.1"
                     /translation="MKTIGLLTSGGDAPGMNAAIRAVVRSAIYYGCKVYGINRGYKGL
                     LEEDLTEMNLSSVGDIIHRGGTILKSSRCEEFKTEEGRLKAVKILKKYKIDCLVVIGG
                     DGSFAGAQKLSDLGFPAIGIPGTIDNDLAYTDYTIGFDTAMNTIIDAIGKIRDTSSSH
                     ERVNIVEVMGRHCGDLALYAGLAGGAETIIVPEVEITVDEVALRLKTTQKRGKRHSII
                     VLAEGVGSASDLEKELKKESGADLRVTVLGHVQRGGSPTVSDRILASRLGVRAVELLL
                     DGKSARVVGIKENKIIDLEISEALAQKKVFDKEAYEMAKILSI"
     gene            complement(81736..85305)
                     /locus_tag="JAM15_01895"
     CDS             complement(81736..85305)
                     /locus_tag="JAM15_01895"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HAT6797027.1"
                     /translation="MNKDFAHLHVHTEYSLLDGFSRVKKLIKRAKELNMSSIAITDHG
                     CMFGVIDFYKTAIKEGIKPIIGCEVYTAARGLRDKDPNYDKYQGHLVLLAKNMEGYKN
                     LIKIVSTSYVEGFYYKPRVDMEELKKHNKGIIALSACLAGDVARALMNRNYEKAKQFA
                     LDYRDIFGEENFFLEIQDHNLPEQKEVNSGLVKLSKETGIPLVATNDVHYVNKEDSKI
                     HDVLMCIQMGKTLNDPNRMRFGSDEFYLKSREEMEELFPYALEAIDNTVKIADMCNVE
                     FDFNTIHLPKYDVPEGYTPETYLRELCFNGLKERYDNPSNEILERLNYELDVIEKMGY
                     VEYFLIVWDFINFSKENNIIVGPGRGSAAGSIVAYTLKITDIDPIKYSLLFERFLNPE
                     RISMPDIDIDFCYERREEVIDYVKRKYGDDHVAQIITFGTMGAKAAIRDVGRVLDIGY
                     NKVDKVAKEIPFALGMTIDKALDTNPNLKELYDQDPETKEIINISKQIEGMLRHASTH
                     AAGVVISKNPVDEYVPLYKHQDAITTQFTMTTLEELGLLKMDFLGLRTLTVIRDTLDL
                     IEKNRVIKNYTEKIDFSKMDYDDPKVYEMLSSGNTLGVFQLESAGMRSFMKQLKPDNF
                     EDIVAGISLFRPGPMDSIPAYIKNKSNPKDVTYLHEKLKPIMEVTYGCLVYQEQVMQV
                     VRDLGGYSYGRSDLVRRAMSKKKMDVMEEERQYFIHGKFDEDGNIEIAGCIRNGVEEE
                     IANKIFDDMIDFARYAFNKSHAAAYGVLAYETAYLKTYYPVEFMAALITSVMGNTDKV
                     VEYIRECKALEIDVLPPDINKSFSKFSVEGDNIRFGLAAVKNVGVNIINNIIAERESN
                     GLFVDLVDLVKRLDQKDTNKRVIESLIKCGAFDNISENRASLMAGYESLLESVSMDRK
                     KNVQGQISLFDAFGDSEEDSDFQQIYSLPKRQEYEERERLNLEKEVLGMYVSGHPLSQ
                     FEKELQEKTSMDNGKLNSLKEEEESYLQMNETDVIMGGMIVTKTIKTTKRNEIMAFIE
                     LEDLYGAIEIIVFPQLLQKYNVILNEDNIIYVKGTLSIKEGENAKLIAREIKDINDDT
                     DFADRNYNSGRTRNVENIKPESGKKLYLKIDSMSDTDTTNNIVEIAKQYPGNDSIYLY
                     PMDENINGKRKAYKMTGALTCICDEFINNLEELLPKDNIKVKA"
     gene            complement(85462..86409)
                     /gene="whiA"
                     /locus_tag="JAM15_01900"
     CDS             complement(85462..86409)
                     /gene="whiA"
                     /locus_tag="JAM15_01900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HAT6797028.1"
                     /translation="MSFSTETKNELARVISGNECCNIAELSALVKSGGSIQIVGYKKL
                     NLKITTELNSIARKVFKLLKKNFNINTTISVNKNQMLKRNNSYVLMVTSEMGSEMLLK
                     KLGILEDKEGFFTINKISENLIKHEGCKRAFIRGAFLGGGSISDPEKNYHMEFVTNNE
                     EFADSLKELINSLGFNSKIVARKNNHVVYIKESEQISDLLSIIGGHHALLSLQNTKIV
                     KEMRNNVNRIVNCETANLSKTVNAAVRQVENIKLIQETIGISSLPENLQEIAKIRIEY
                     EDMTLKELGEMLEPPIGKSGVNHRLRKIEEIATDLKKKS"
     gene            complement(86426..86851)
                     /locus_tag="JAM15_01905"
     CDS             complement(86426..86851)
                     /locus_tag="JAM15_01905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HAT6797029.1"
                     /translation="MREEVSAGGVVLFGNTILLLRKFNGDWVLPKGKVEEGENNQEAA
                     LREVSEETGVKADILKYLGEIHYTFKENWDENRAVHKTVFWYLMQAKNMDTIPQKEEG
                     FIDAKFIHLDRVVDLARYDDEKEIIKVALQEIKKRLKKN"
     gene            complement(86920..88026)
                     /locus_tag="JAM15_01910"
     CDS             complement(86920..88026)
                     /locus_tag="JAM15_01910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HAT6797030.1"
                     /translation="MTKLLIIVGILGWIALIVSLFIYKKAKNEKVKLFQRSIVENREP
                     NVVVIGGGTGQSVFLRGLKHTTQNITAIVTVADDGGGSGVLREDLGMLPPGDIRNCLL
                     ALANIEPTMNEVMQYRFTEGLLKGQSFGNLFLAAMNGLYGNFEKAVYKLSEIFAITGR
                     VLPVTLEDVNLVAKLENGNIINGESSIPEESKIQKSSIDKIFLNPKDVKPLKDVIASI
                     YDADIIIMGPGSLYTSIIPNLLVEGIVDAIKSSVAPKVYIANIMTQPGETEGYNVLEH
                     VNAIVKHTDENLIDYVIANNEILPEEMLDLYKQDGAEQVLLDKKQKDKLKEMGIKTVE
                     KNLIEIKNNYIRHDAKYISNIVIELALNHNYNKS"
     gene            complement(88038..88895)
                     /gene="rapZ"
                     /locus_tag="JAM15_01915"
     CDS             complement(88038..88895)
                     /gene="rapZ"
                     /locus_tag="JAM15_01915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HAT6797031.1"
                     /translation="MKFVIVTGLSGSGKSETMRALEDMGFYCVDNLPPALITKFAELC
                     YQPNSSIDKVALGIDIRGRKFFEALHESLNYLEKENYEYEMVYLDCNDDVLLKRYKMT
                     RRNHPLAKDMQIPEGIKMERKIMEPLKELSTCIIDTTNMKPKDLKEEIKKIYSSGEDN
                     PNLTISVVSFGFKHGILADADLVFDVRFLPNPYYVEELRAKTGDDKEVRDYVMNSKIS
                     EEFYVKLLDMIHFLVPQYIEEGKQHLVIGVGCTGGRHRSVTITNLIAEDLSNKGYRVV
                     KKHRDSMLR"
     gene            complement(88926..89639)
                     /locus_tag="JAM15_01920"
     CDS             complement(88926..89639)
                     /locus_tag="JAM15_01920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HAT6797032.1"
                     /translation="MKILADYHTHTLYSHGKGTIEENVKVAISKGIKTIGISDHSYKH
                     IAYGVKKKDILKMREEVDYLNDKYTDINILLGMECNILDDKGNIDMDDKFIRDFDYIM
                     AGYHFGSTPTSLRSLLNHCNNYIFKTEKAKEYNTKAVINAISNNDIFIITHPGDKGDV
                     YIEEVAKTAKKTNTRLEINSSHSFLNVNQLNKIKGLENKFIIGSDAHCPERVGDFELA
                     MKTISDSNLDISLVENIII"
     gene            complement(89643..90557)
                     /gene="murB"
                     /locus_tag="JAM15_01925"
     CDS             complement(89643..90557)
                     /gene="murB"
                     /locus_tag="JAM15_01925"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HAT6797033.1"
                     /translation="MNNQDIYINLLNILSKEDIKVDEPMKKHISFRVGGPADILVRPR
                     TEEQLKNVLRLVKKESIPYLIIGNGSNILIKDGGIRGVVIELADNFNSYEINDTRMTA
                     QSGALLSVLGKALQKQELKGFEFASGIPGTLGGALAMNAGAYGGEMKDIVKSVRLMDM
                     EGNIFELSNEQMEFGYRKSIISKNGYIALSAELELQEGNYDEIKSLMDDLATRRITKQ
                     PLNFASAGSTFKRPTGYFAGKLIEETGLRGLTLRGAQVSEKHCGFVVNQGEASAKDIL
                     DLIYVIKSAVYAKFGVMLEEEVKILGED"
     gene            complement(90830..91600)
                     /locus_tag="JAM15_01930"
     CDS             complement(90830..91600)
                     /locus_tag="JAM15_01930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HAT6797034.1"
                     /translation="MSKGFLTPGETAQATISAGIKKANISTQNAILLGLFGGAFIGFG
                     ALGSMIVSQTFGKIDPGVASFLSAMVFPVGLMLVVVAGAELFTGNTLMAIALMDKKIT
                     LGKMLRNWGLVYFANLVGSILLVALVFYSSTLTGDAATKAIAVAEAKVNSTIASMFLK
                     AILCNILVVLAVWMSTASQDIMSKLASCWTVIMLFVLCGFQHSVANMFFIPMGMALGA
                     NITMVQFITNLVFVTLGNIVGGSIVVGGIYYLCYVKNS"
BASE COUNT        29353 a        16002 c        10051 g        36276 t
ORIGIN      
        1 ttattaaatt tatttttata agaaaatata gcaataaact ataaacaata catcatttta
       61 attaatttag atgtatatac tataaaaatt aaataaaaat agagactaca ctttaccatg
      121 tagtctcctt ctttctggtc atatttagaa attcacattt attgttactg cttttccgcc
      181 tctatttact gttatttttg tactagcacc ttttgagaaa gtatacaact ttttatttaa
      241 atcattcata cctgttatat ctgtatctcc tactttagtt ataatatccc ctacctttac
      301 tccagctttt tctgctgatg aaccagatat tacttctgca acataaacac ctttatcagt
      361 acttaatttt gtacctgttg ctgcttcata atttgataca tctgtacctt ttatgcctaa
      421 agttactttt tcatattttc catttttgat tacttcttca actatactct tagctgtatt
      481 gattggtatt gcaaatccta atccttctgc ttgagaagct tttgctgtgt ttataccaat
      541 tacttgacct ttttgattta acaatggtcc tccactattt cctgcattta tacttgcatc
      601 agtttgtaat aaaccagtca tattagtttt ttctgtttgt atagttctat ctaatccact
      661 tattatccct tgagtaactg ttttttgaaa atctaatcca agaggattac ctattgctat
      721 tgatatatct ccaactttta ctttgtcact atcagcaaat tctgctggtg ttagtccagt
      781 tttatcaacc ttaactatag ctaaatcaag ttgttggtca aaccatacta ctttacctga
      841 agttgttgaa ccatcattga ataatacatt tacacttgta gcttgaccat ctgatataac
      901 atgagaatta gtaagtatat atccatttga atcaactatg attccagttc ctacaccttg
      961 tgtttcagtt ggtattgcaa acatattact agtatcaaca ctagttgttg taatacctac
     1021 aacagatggc gtagcttttt ctgcaactgc ttgataaata ttttgactct taccatcatc
     1081 atttacaact attggcgtag aacttcctgt agatttgctt actaaattgt ccttaactaa
     1141 aattattgtt agaaaactac taagtattga acttattata gcaactaata ttactaaact
     1201 tatccctttc tttcttcttg acatctcata ccactcccta tcttaatata atataaatta
     1261 tcaaaatata tttttcccaa tttttcataa aaaaaatgaa atcatctatt ttgagtaaac
     1321 tccttttcga tgatttcatt atattatttt aatcttaatt aaaccttaac tatttaaaat
     1381 tatttaagtc ttttttctag ctcttccttt tctttttcat aacctggttt gcctagtaaa
     1441 gcaaacatat ttttcttgta agcttctact cctggttggt caaatggatt aactcccaat
     1501 aaatatccac ttattccaca agccttctca aagaaataaa ctaaatatcc aaaattatac
     1561 tcatctagtt gaggtatatt tattactaaa ttaggtactt ttccatctgt atgagccaat
     1621 agagttcctt caaaagcttt atgatttaca aaatctacag tcttacctgc taaataattt
     1681 aaaccatcta agtctacttc ctctgaactt atagttatat ttctcttaca gttttcaaca
     1741 ttaagtactg tctcaaataa aagccttttt ccatcttgta tgtattgacc catagaatgt
     1801 aaatctgttg agaaatctac agaagcaggg aataaacctt tattttcttt tccttcactt
     1861 tctccataaa gctgtttcca ccactcactt acataatgta gttgaggttc atagttcact
     1921 aataactcta catcttttcc ttttctatgt aaaattgttc tagcaacagc atatctataa
     1981 ctatcattac tttttaagtc aggattttga aatgcttctc tagcatcatt tgcgcctttc
     2041 atcataacat caatatcaag tccagcagca gcaataggaa gtaacccaac tgctgtcaat
     2101 acagaaaaac gaccacctac atcatctggt attacaaaag tctcatatcc ttcttctgta
     2161 gctaactgtc taagtgcacc tttacttgca tctgttgttg cataaattct ctttcttgct
     2221 tcttccttac catacttttt ctctaagtaa tctttaaata ttctaaaagc cagagctggt
     2281 tctgtagtag tccctgattt agatattaca tttacagaaa tatcctttcc ttcaattata
     2341 tctaataaat ccataatata tgttgagctt atattatgcc ctacaaaata tacttctgga
     2401 gcctttcttt gctctttttt aagtccattc ctaaaagaat gacttaccat atctatagca
     2461 gctctcgaac ctaaataaga gcctcctata cctattacca gaagaacatc tgagtctgat
     2521 tttatcttct cagcagattt ttttattctg tcaaactctt ctttatcata atttttagga
     2581 aggtctatcc atcctaaaaa agtatttcct aaaccagttt tattatgtaa catgtcgtgc
     2641 gcaacatcta catatggttg catgacatct atttcgtttt gacaaaaaaa ctctgtagct
     2701 ttactataat caaaatttat ttttcccatt taaatccctc ttttcagcat attcgtttta
     2761 aagagattat aacacaaaat ataggtgttt tttttaaaag tttgccacaa aatcatacat
     2821 atctcatcat ttattatcag gaaatcgatt cttctaaata ctataactat gtataaattt
     2881 aaaaatttta gtcaaataaa tttacaaaaa aagaaactct aaacgtatca tttaaagttt
     2941 ctcttttatt tatcctctat tttaaatttt atattatttt aaattaatta tttttaatca
     3001 tttcctaatc tcttcgctat aacttgttgt gctatattga cagcatggtc agatattctc
     3061 tctaaattac ttattacgtc taaataaata actccatttt ctatactaca tagattattg
     3121 ttcaatctat acatgtgatt agctctacaa gatttctcca ttatatcaac ttgttcttca
     3181 atttttataa ccttacaagc taaatcaaca ttatcagttc tcattgattc taatgcataa
     3241 gtatatgctg aaacaactct attatacata acatcaagtt cagattgtcc ttcttctgag
     3301 aaagaaatat ttgaatctat tgcaacttgc gacaattcag ctatattttt agcgtggtca
     3361 ccaattcttt ctatatcatt gactgtatta aacaaagtat ccacaacttc tcttgaatca
     3421 tcatctaaag gtgcttttga aagtttaagt aagtaattta aaatagcttt ctgtaaatca
     3481 ttgattaatc tctctcgtct atatgtctta tctatttttt cagttgaatg ttctactaag
     3541 gcttccatag atgcatttag gctttccttc gccttctcac ccatacgaag tgcttctttt
     3601 atcgtatttg caagagctat agaaggagtt tctatcattc tatcatctat atatttaata
     3661 gttttagttt catcttcatc tatatcacct gctctatcag gaacaagctt tatagctagt
     3721 tttataataa gatttgtaaa tggtaaaagt atcaatacag atattatatt aaacaatgta
     3781 tgtgtattgg ctatttgtct tgcaacattg cttggatccc aacttgtaac catgcttact
     3841 actggtttat tcaagaatat taagaatatc accgttccta aaacattgaa gattagatgc
     3901 atcatagctg ctcttcgtgc atttttgtta gcaccaatac ttgataacag tgaagttaca
     3961 catgtaccaa tattttggcc ataaagaatt ggcagtgctg ctgataatgg cactagacct
     4021 tctgctgcca gtgcaaccaa catacccata gatgcacttg aactttgtat tattgctgta
     4081 atcccaaatc ccaataataa tccaagtagt ggatatctac caaatgtaac aagtaggtca
     4141 gtaaatcctt gatagtctct tagtggctcc actgccatct tcataaaatc catacctgta
     4201 aataatatac caaaacctat aagtatttcg gctatatttt ttattctagg cttatttcca
     4261 aataaataaa gtataatacc tacacctaat gctactgggg ccataccagt taagtcgaaa
     4321 gataccaatt gggctgtaac agtagtccct atattagcac ccattataac tcctattgcc
     4381 tgttttaaag tcattattcc tgcatttacg aaaccaacaa ccattacagt agtagcactt
     4441 gaactttgta ttactgctgt aactcctgta cctaccaaaa ctcccataaa taggttacta
     4501 gtaagtagtt ttattatctt ttttagcttt gtcccagcag atttttgaag accttctccc
     4561 ataaggttca taccatataa gaacagacct aatccaccca ttagacttat tataatgttc
     4621 aaattatttc ctccttgtaa agagattact gtatctaaaa attttataac ctattgtatt
     4681 ttatcaaatt ataggagtga taatgttaaa ttcatgttaa atattaaaaa atcattaagt
     4741 ttatgttaaa tttttgtatt attggtgtat ttttgtatta ttttttctgc acattttata
     4801 ccatcaactg ctgctgtaac tataccacct gcatatccag cgccttcacc acatggatat
     4861 agattcttaa tactcactga ttctaaagta ttttcatctc ttactattct tattggtgat
     4921 gatgacctag tttctactcc cgtcaaaaca gcatcataca ttgcaaaccc attcaatttt
     4981 ttatcaagag atataaacgc ttctctcata gtctctgtta cgaagctagg caaacattca
     5041 cttaaatttg taagtgtata tcctggtcta tatgatggct caacacttcc taaattcaaa
     5101 gaagtcttat tgtttataaa atctccaaca agctgaactg gtgcattgta attttttcca
     5161 cctaattcaa aagctaattt ttcatacttc tgctggaaat gaacacctgc tagtggatta
     5221 tcactcttaa aatcttctgg cgttacattt actaaaaatg cactatttgc atttatttta
     5281 tctcttgcat gttcactcat accatttgta actatttcaa aatcatttga tgcagatgct
     5341 atgacactac ctcctggaca catacaaaaa gtatatgctg ttcttccatt tgaaacatgc
     5401 tctataagtc tataatctgc agctcctaac ctaggatgat tataaaaatc cttgtactgt
     5461 gctttattta ttaaatcttg tggatgttca actctagctc ctattgcaaa aggtttttga
     5521 actattttta tacctcttga atacaacatt tcataagtat ctcttgcact atgtccaaca
     5581 gctagtataa ttgtatctgt atctattttt tcagtatcat ttattattac agattgtata
     5641 gaatcatttg atacaactat atctgttact tttgaattaa atctaacttg accacctaaa
     5701 cttattattt catttcttat atttttaact acatttttta atatatctgt tccaacatgt
     5761 ggcttatgtg agtataatat ttcatctggt gctccaaact gaactaactc ttctaatact
     5821 tttctacatc gtatatcttt tattctagtt gtaagtttac catccgaaaa agttcctgct
     5881 ccaccttctc caaattgaac gtttgaatta ttttttaatt ttctagttgt ccaaaaatca
     5941 cttatatctt tggttctact gtctacatca agacctcttt caagtatgat tggttcataa
     6001 cccatttgag ctaaaagcag acctgcaaat aaaccagctg gtccactacc aattaccaaa
     6061 ggattattct ttaatttttt atcacccaca ggtacattta tgtatctgat ttcctttatt
     6121 tttgttacat cttttatttt tgagttaagt attttatttt catctttgac ttctacatct
     6181 acagaataaa caaattccat ttttcctttt tttctagcat ctatagattc tttatatata
     6241 ctatatttga ctaagttttt ttcttttatt tttagcttct taagtacaac atcttttaat
     6301 aaagatatat ctttatcaat tccaagtttt acattagata ctcttaacat attgttttcc
     6361 tctcttagat tgtaatataa aaaagctagg gttattccta gctttctaca aatataactt
     6421 ctatattctc ttttactaga ttttctaccc aaatctcatc tagcacaaaa ttctttattt
     6481 tgtttacaac aagtgtttta tctaaatctt ttttcaagtt ttttactaag accattgctt
     6541 caactgattt atgcaatctt tcaacataca gagaattaac tttaatcaat acaaccctta
     6601 attcacacac atataacttt tcactaccta aggtgatttc atcatcatat tcatatacac
     6661 taaattcata tgtattttca taaggtgtta tattttctat tcctatatag tccatttatt
     6721 tatccttttt tagttataag acctcttata accttcatgt tattaaacac cttttctaag
     6781 aagttctctg cttcttcatt gtctaaaagg tttatttcaa ggttttcgtt ttctacaata
     6841 cctttagatt tacagtactc tttagcaaca tttattagtt catttttttt atccatagat
     6901 aaatcaaact ctttatagtc tattattata tattgtttgg tatcaggtga tacaccatta
     6961 ttatatccta tttctatatg ataaataact gcatatattt cttctccgtt gtacacaggt
     7021 acagctgggt tagattttat aaagttcgtt gatacagcaa ttgcatttcc taaactaaga
     7081 ctcattatta atacctcttt ctaaacatta tacatatatt atactataga ttctttatct
     7141 atgacttaaa gctttttata attaattaag atatttttaa atctttgtat ctctttccta
     7201 gtgtactaga gcttatatcg tatttctttg atatttgaac ttgagttata ggttgtcctg
     7261 cttctttttt aacatagtat tcaacagcag ctgcccaacc attttcagct ccttttatat
     7321 tttcatgatt tttcttatat tcattccaaa actctataca tgcatctata ttttcttttt
     7381 ctacattttc tttaagagta tctaaaactt tacattcttc ttcagctaat tcattttctg
     7441 aattaacttt tgtatcgttt ttatctcttt ctctctttaa gtattcagct atacttgggt
     7501 ctaaaagctg ttgtatatac ttgtatagta tatgtgtatg ataaattaag aacgacttca
     7561 tatctttgta tacatcttga tattgattga atagattcat aatatccttt agaattatat
     7621 ctttaacctc atttgatata cttatagtta tatctatcaa tatgttagtt ccttcaatat
     7681 caactattct agctatcata caacttccga ttttaaaact tctcagaagt tttacatctt
     7741 ctgtacaaag ttcatttcca cttaaacagt cctttaatac tatttttcca gcagaaactt
     7801 cttttacctc ataaatactt acgtatgatt caaacatact ttttaatatt gatacttctg
     7861 attgacttag gtttgcacca ttttcttcaa gaaaaccaac tgtcataacc tttttatttt
     7921 ccattatgtg gtcttgtatt aaataagtat taaaaaatct ttcaaatttt tcatttacac
     7981 tatcattttg cattatataa aacatttctt tagctttttc acattcttct ttaaacttat
     8041 cctgtcttga ataatcatat aactttgaat ataaatctgt atattgtttt tgtgaaagtt
     8101 cagtttttct gcatgctctt tctgaaacaa tatctttatt taaacaacat ttcttgtatt
     8161 ttttgccact tccacaaggg catagctcat ttctccctaa caatatgact tccactccct
     8221 tattattaaa ttaaagtaca atttgttatt ataccatttt tttattaatc aatctatagt
     8281 ataagtaaat attctattaa attcacttat attttggtac aatatattaa ctttaattag
     8341 gatttcgata aaatcatcaa caatccctct tgtagaaatg aattatcgta aaactaattc
     8401 ctctataaaa ttttattaat tgataatagt tttttacttt atctattctt ttttgttata
     8461 tgactctaac tgtcatttta cattcaacaa tattgtcttt ttcttgttta tattcatttg
     8521 gaatattttg agcatcaaaa ttattgactt ttaatttgtt aatttctatc ttttcaaatt
     8581 tattatttaa tcttaacttc ttcattacac cttcaagttt caacacattt tcaagttctc
     8641 cattaacttt tatttctaaa ttaacttgtt ttttattatg attatctaaa ctactttctt
     8701 gattaatata ttctatgttc acaatatctc tcagttcatt ttctactaat aacactatat
     8761 ctttatttgt ttttttatct aaaaatgagt tattaaaatt atttttcaac tcttcatttt
     8821 tatttaattc aacactttct atatatttat catctatatg cttattatcc tttatttgat
     8881 aattatcttg attatttatt ttatttatta tattttgctt ttcattcttc aaactagtta
     8941 ggttttcttc caaataactt actgctatat cacttgccaa tataataact aatattaaca
     9001 atattttaag tagatttttt tctctattat ttaatctcaa aaataatcac ccatctaact
     9061 ttttattcta aatctataat attctccatc tcttacaata ctgtctatgt aataatattt
     9121 tatgtacttt attttcctta ggttgtttaa aacatctaaa tcactacaca caccttccat
     9181 ctctagctta tttttatcta tcgatatttt agtaatacta tttattccaa ttgtttcata
     9241 tatttttttt atttcattaa gttttatttt agaaaatttc tctctagttt tatctgttgt
     9301 tggtaaagtg tgctttgatt tacccactag cttattttga tttatataat cttcaagttc
     9361 atttatagat ttcacataca taaatgattt aaataaaata cacgttaaaa ttaagactat
     9421 tattatttta tagattttat tacatggttt agttttttta aatccattaa gaaaatttat
     9481 tgttttatcc actttcactt aaataatcat tcctatacta tttatataat ttatcctatt
     9541 gtcttctaaa tctgcatcaa aattattttc tacttttact ttatctttta atcttaatgg
     9601 atttacttca atagatttat ctgtatattt aaagtattct tcaataaaac aattttctat
     9661 accatagtaa taaacatact taaaatccct taataatctt tttatgaact catatgattt
     9721 tccctctttt gatagcaagt atgtttctct tattttttta tcttttgtta tatttataat
     9781 taactgactt tttttacatt ctataaatac cccttcttct gaaaaattct ctattaaatt
     9841 taagtttata agcttttgta atatatcaaa atttatattt atagtctttg gattcatatt
     9901 tagattttct gaaatgttct taattaattg aataatactc tttgggaaaa gaattacttg
     9961 tatattcaat ttatcatttt tagaatttat aactttatat tttattgaat agttatttat
    10021 gtttattgga atgtattgtg ttatttcaaa ttcaatcatg cttaatatgt ctcttttttt
    10081 cttagtattt agaacttcaa catttctaat gactatatct tgaatttgaa tgttaaagta
    10141 taaattttta tataatattt ttgatttacc aatctcctct tttacaaatc taactacatc
    10201 ttctatatat ttaatcttct caatcgaatt actatcattt tttatatcaa agttaatctc
    10261 ttttataatt gatttatcta taaaaacttt tttatgactt tttcttaaaa atacaagcct
    10321 tatataatca tcatttattt ctaagtttat aattttttta attatagcca tctccttctt
    10381 aaataaaaat aattttaaaa cttacagcaa tcaatataaa atattatttt ggataaaatt
    10441 gtttagaatt tatatttacg cttatatctg ttccgctatc atttatgaca agttcgaatt
    10501 tacctgatgt actctgagga actggaacag tatttaggta tcccttttcc ttcaatgttt
    10561 ctacacttag agagtctatt gtcttttcat catcattaat tgccatgcta gctgcggtta
    10621 ctatattagc agcattcgta tagtctgcat ttaatttggc actttcttga accttactat
    10681 acttaactaa tgctatacta gatataacgc ctaaaatagt tactactaca atcatttcaa
    10741 caagtgtaaa tccttttcgt tttttattta tcaaatttat caattaaata ttctctcctt
    10801 ttcaaaagtt tcatctaata aaatttattt ttctctctaa aaattagtaa ttgcatcaaa
    10861 cataggaaca accattgcta aaataaaagt gccaataatt aatcccataa atacaattag
    10921 cataggttct ataaatttca ttatttgctc tattttgtta tttaattcat tttcataaaa
    10981 tttatttatt acatttagac ttttatctag tttcccactt tcttctcctg tatttgccat
    11041 tgaaataaat aattttggaa aaacatttgc taaattcaaa gatttaccta tgctatttcc
    11101 tttttttata taattattag aaatctttaa cctttcataa ataaattcgt tgtctataac
    11161 actagctgac atgtctatag cttccacaat ttgtattcca ctgctaatta aaacggacaa
    11221 tgcccttgaa aatcttgttg tagctactaa ctgattaatt ttttttataa aaggtatttt
    11281 gaattttaac gaattaatca atttttttat attatcattt gttataaaga aataaatgct
    11341 tcctattgaa aacaatataa aactaaatat tatataagct aagttatttg taaccactgt
    11401 agatattccc attaaaactc tagttattaa aggtggttca attccattgt tggtaaaaac
    11461 cacctgaaaa ttaggtatta caaatacgaa tataaacaac attgataaga tagataatat
    11521 tataagtatt attggatata ttgaaatagt tattattttc atttttaatt tgtattcttt
    11581 atcataataa ttagataaat cactcattat tatatctaag tttccactag tttctcctgc
    11641 ttttatcata cttataaaga atttagaaaa tatacctgtt atttgaaatg attctgctat
    11701 tgagttacct ttttgaatat gatttgatac tatactaagc aaattcttta cttttttact
    11761 tgactgactc tcaatgattt caaatatttt tgtaatttca catccagatt ccagcaatat
    11821 gcctatctct ttgcaaatta ctctaatttc tttatcactg attctattta atactaaata
    11881 aaacttttct aaattataaa atatattttt agataatctc atgtactata ataccttcca
    11941 aattatatta attacaatta aataaactta atattttcta atttaatgca tttaatttta
    12001 tttcacttaa atataattta tactcaaaca tcttaattaa aatagattaa ataaagacaa
    12061 ctgaccaaac gaagtttaac tatacaattc agttaaatca tttcatttac tactaaacac
    12121 tcttctaatg tcgttatttt ttcatttatt agtcttttac agctatcttc aaatgttatc
    12181 attccattat tttgtgccac atctttaata gtactagaat cctccatatt tcttatacat
    12241 gtctttatat catcattaat ttctaagatt tcataaattg ctgttcttcc aaagtatcct
    12301 ttatcattac atttttcaca ccctacagct accttagtat ttacatctcc actaaaatta
    12361 tcttttatca taatctcatg gctacaatga ttacaaactt ttctaaccaa cttttgagat
    12421 ataacaccta taagagaggc atttaaaaga tatggtggta tttgcatttc tagtaatcta
    12481 gctatggaag atactgcatc attagtatgt aaagtactta taactaaatg acctgttata
    12541 gctgctctta ctgctatctt agctgtttct gcatctctta tttctccgac cattattata
    12601 tctgggtctt gtcttaatat cgctctaaga cctacatcaa agctcaaccc tacttttgaa
    12661 tttacttgaa tctgacttat gccatccatc ttatactcta caggattttc tatagtcata
    12721 atatttttat ttattccttt taaatcattt aataaggaat atactgttgt agtctttcca
    12781 ctacctgtag gacctgtcac taataatact cctgctcttt tatttattat acgatttata
    12841 gattttatag cttcctctga aaaaccaagt tctaatttgt cttttaaaaa agtatctcta
    12901 ttaagtatcc tcaaaactat tttttcacca tagacagttg gtattgatga aactctaatg
    12961 tcaattaaat ttccacctaa ctttatatcc accctaccat cctgaggaag ccttttttct
    13021 gttatatcca ttgatgcctt taattttata accgtagaca atgatggata gacatcaact
    13081 aaaaactttg atacttcctt tagttctcca tctaccctca ttctcactat taaatgttct
    13141 ttaaatggtt ctatatgtat atcacttgca ttttctttta tagctttttc taaaagattt
    13201 tcaaataatt tttttgcata atcctcatca agttcaaagc tattataata tttttcaatc
    13261 ttttcactta taagttcttt tttctccttc ttcaatataa tttctttacc tgtagctaat
    13321 ctcaagtcct gtagagcata aatatcctca tcttctattt ctacaactaa attatcatct
    13381 tgaaactcaa ctggaaatac attatatttt tttgcaagtt tttccggtat taacattggc
    13441 aaactgcttt cctctaatat aatcttaatc accctttata tactttaatt tattaggtat
    13501 attcattttt ttcatagaga tattttcttc agtttttatg cttattttca ttggataatt
    13561 ggtttgtatg ctatctaaat atttactacc tttatctaca taattagata atttctcctt
    13621 atctccaatg cactttattt catatggttg tgctacagga actccattta tatttatatg
    13681 gcttcctgca agtacaactt ctgaatattg attaattctt tgaccattta tttctatgta
    13741 ttttcctccg tttactttta attcatttat aacttttaca agaatcttat tatagtctat
    13801 actattagct atattccctg ttttttcatc tatagcatct atacttaata ttatcccact
    13861 accctttaca tctgaatatg atagactatc tctaagtgtt tctatttctg atatttcttc
    13921 agaatttttt tgattttgtt tcattgaatt aatttcttta tctaacttgt ctttctcttt
    13981 ggttaattct tttatagatt ttcttgtcat ttttatttct tttcttattg acttgtcttt
    14041 gcttgtataa actgtttctt cattgctata atctctaaat atggttccaa caagtatacc
    14101 taaaatagta cttgctagta ttataaacac atattgtttt ttcatactgt attgctcctt
    14161 acaaatttat ttttatatga taattttctt taattaaata ttaaacattt acatatgctt
    14221 attatatcaa agttatatat taaaattcat ctttagtata taatatcata cattgaactc
    14281 ctatcactaa tttaccaata tcaagtatgc atttttagat gttcttaaaa ttatataaac
    14341 tttcaataaa cattgttgtg atattataaa aaaacataaa ttaggaaagg aaataataat
    14401 tatgaaaaac aaataatggc tttggagatt attaatatca ttttttagca aaaaaaagta
    14461 aaatggcata gcctcaaagc tacaccaatt tactaaaaat tatattatta ttaacattaa
    14521 ttttaaacat atacgtttat aagttttcct catattttaa aattctttta attaacttat
    14581 ctcttaattt ccctacttca tcaaatctca tattaggact atagtaactt tctataatat
    14641 catgtttaga cttggctctc ttaagattta gtactgccca acaaattaaa tcatctaaaa
    14701 ctttttcatc aaatttaata tcttcttcat atttaagtag tttttctcta tttaaaaact
    14761 gatttaaatc aattgtatct tcttctttaa aagtcgtact tatagttatg cctatatcta
    14821 aatcagttaa tagtacagtt tcaattttct ctggaataag tggataatga taaacttcta
    14881 catttaaacc tttttcaata gctttcttat atactttgtt taataatgta gttttcccag
    14941 ttcctatttc tccatctaaa taatagactt tctttacatc ttttaaaatg ttttctgtat
    15001 aatctaaaca ccctacagga gttatagctg aaccaaataa atgcttttct ctttttagat
    15061 ttcctgtgct tttaactcca tcaaataacc tttttataaa ttcttctgtg accaaattta
    15121 ctttgccata atccatacaa tcagaatatt tttcttctat gtctctaaaa attggttctg
    15181 ctgactttaa aaacttaaat gctcttttaa atgaattact aatatcttta tcataaactg
    15241 atatttcttg tttattcttt tctaattctt ctgtattcca gtaatcacct aaattaatta
    15301 tctcatccaa agctccaggt agctttgggt ccatagtatg tggggcagtt gcatccataa
    15361 gtaccacgcc taatttcttt ataactaaac catccaacga acttgggtca gaaggacaat
    15421 gatataaatc aatatcatat cctctatgca aaaactcttt ataaattttt ttcataagtg
    15481 aggattttcc tactccaggt ccacccttta aacaaaaaac tctttttaca ttttcaggaa
    15541 ttatatagtc aaaaaaagaa tatgagcctt gtgatgtatt tccacctggg aatgccttct
    15601 ttacctttcc ttccatatta gcgcctcctc ataatttaca atatctctta attaagatat
    15661 tcatattata agaattttat tacagctttc tgattttgac aaatttaaaa cttaccatct
    15721 aatactaata acatattaat tttatctaat tattatagat tctcatactg taccttattc
    15781 tatctataaa tacaatttaa gtgtccatat tgaaatattt gtattgtaat acagctggat
    15841 attacttaaa tccaattgtt tccattataa ttttatgtta aaataatatt acaaaataca
    15901 tctgtttttc ttcataaacg ggtgaaagtc cctatcggcg gtaaaagccc gcgagcctta
    15961 tggcataatt tggtcatatt ccaaagccga cagtaaaatc tggatggtag aagaaaatag
    16021 tatatgagta cctttatgta attttacatg agtaatctat acaaatcctt caactaccgt
    16081 atttattcat gaaattagac acattcaagg tacctaatat acaggtgctt tttttgttgt
    16141 ttattttaca attatatcgt acttataaaa tctattaaga ttggagtgtt atcatgaaac
    16201 aaaaatggat agtattgatt atcatctgta ttggtgtatt tatgtctact cttgatggaa
    16261 gtatactaaa tattgcaaat cctacaattg ctgctgactt taaaattaac atgtcacaaa
    16321 ttcagtgggt tgtaacagct tatatgcttg ttgtaacagc tactatgtta ttttttggaa
    16381 aactaggcga taaagtaggt tcaaatcgtc tatacacatt aggatttttt atatttacaa
    16441 taggttcttt tctgtgtagt atgtcaaaca atttatcaac attaatttct tcaagaatct
    16501 ttcaggcagt tggagcaagt attttaatgg ctactgggct tggtatagtt tccaatgcat
    16561 ttccagcaaa tgaaaaagga aaagctatag gaatcactgg agctgtagtt ggtataggaa
    16621 atatgagtgg tcctgtaatt ggaggtataa ttttagaaca ttttggatgg ccttctattt
    16681 ttattatcaa tatacctatt ggtattatag cagtctttct tggcattaaa tttctgccta
    16741 aacctgtttt ggatgaacaa aacaagagct ttgatatttc aggtcttcta cttttcgcat
    16801 cttgcactac gcttatatta cttgcaatga atgagaaggg taatacaaga ttgtatttag
    16861 gtataacagc acttataatc ttcttattgt tggcactaag agaagtaaaa tttgaacaaa
    16921 gctttattga cctacctcta tttaaaaata gaaactttac tgtaggcaat atcattggag
    16981 tagcttgtta ttttcctcaa atggcagtat cttttctact tccattttat ttagaacaat
    17041 taaaaaattt atctcctatg atggctggtt atgtaatgac tgtacatcca cttattatgg
    17101 tacttatagc acctattgca ggttcacttt ctgataaaca cggtgcaaaa aacattctaa
    17161 cagcatcttt ttcatttatg accatctcac tagttggaat ggcactttta aaagcagatt
    17221 ctccattgta tcttttaatt gtatgtttag ttatttttgg acttgggcta ggagcattta
    17281 gttcaccaaa caatagtagt attttagcag atgttcctcc tcaaaaacag gggtacggag
    17341 gcagttttct tgcaactatt cgtaatttat catttgctct tggaacagca ttttttagta
    17401 gtttttttgc acaaagtctt acatacaatc aaaagtttaa aagtcacaca tcagcctatg
    17461 ttatagctag caatcagtct tattggattg cagcatcagt atgttttata gggcttatac
    17521 taactgtttt ctttatgaga aaaacagata aatctatttc ttaaatgcta tttattgctg
    17581 actacataag tcaataattt tttagttgaa ctaatttata ctaattttcc cataacttac
    17641 taaaatttat tagtatttag caaaattact gatatttatt gtttataaac aataaggatg
    17701 ccaaaaaaag ttcattaaaa ctattttaag gcatcctata ttttgcttta atattaatat
    17761 aattaaaact aactattatt acatttatta ttcaaataaa tcttatgtca atatttaaca
    17821 ttttaaattt aatctactgt tatttcatat ccatgttgat tgtattgatt tacaatctct
    17881 tcccataatt cctcaacacc agtctttttt agtgaagaaa caggaattac tttttcacta
    17941 ctttccattt gcaatttttt tcttattata cttatgtgtt tttgatattg tcctctagat
    18001 attttatctg ccttagttgc aataactaca cagttatatc caaagtgctt tatccattca
    18061 tacataagct tatcatctgc tgtaggctca tgtctaatat ctacaagtag gaatatagaa
    18121 cataactctt gtctactttc tagatatctt tccattatac ctccccactt ttctttttca
    18181 gacttagcta tctttgcata tccatagcct ggaaggtcta caaaataaaa ttcattattt
    18241 attagataaa aatttatagt tctagttttt cctggtgttt gactggttct agcgaagttt
    18301 cttctgttaa gcaatgtatt tattattgat gattttccaa catttgacct accagccaat
    18361 gctatctctg ggattccttc tgctggatac tgtgatttat tcacagcact catagttatc
    18421 tctgaacttc taattttcat tattttcacc actctttaat aaagcttgtt ctaatacttc
    18481 atccatatgt tctacaagca caaactccat tttttctttt acattttctg gtatttcatc
    18541 taaatcagct tcacattctt taggaattaa tacttttgtt ataccagctc tatgagctgc
    18601 taataacttt tctttaaccc ctcctactgc taagactcta cctcttaaag ttatctctcc
    18661 tgtcattgct atatttccag gaacaggtct tttagtaagt gctgagatta ctgcaagagc
    18721 catagttata ccagctgatg gtccatcttt tggaacagcg ccttctggaa tgtgtatatg
    18781 aatatcattc gtcttataaa attcagggtc tatatcaaac ttgtccacta ttgaccttat
    18841 ataagagata cctgtcttcg cagattcctt cataacatct cctaattttc cagttaatac
    18901 aatttctcct ttacctttaa gtacgtttac ttctacttca agtgtaactc caccaactgc
    18961 tgtccatgca agaccattta ctaatcctat ttgaggatta acttctgcaa gttgatactt
    19021 aaacatgtct tttccaagat atgtctctag gtcagactta tttataacaa cctcttcaag
    19081 agttgggtct tcaacgtatt ttttggcaac ctttctacaa atcttaccaa tagttctttc
    19141 tagtgttctt acaccagctt ctcttgtata atggttaatt atacttctta aagtttcatc
    19201 atctattttt ataaagtttt cttttaaagc atgttcttta atctgttttg gaagtaggta
    19261 ttttcttgct atatttaatt tttcttcttc tatataccca gatacttcta ttacttccat
    19321 tctatctaat aatggtcttg gtatattacc tagactattt gctgttgtaa caaatagtat
    19381 ttttgataaa tcaaaaggta tttctaagta atggtccaca aagtccttat tttgctctgg
    19441 gtctaatact tctaacattg ctgaagctgg gtcaccttta taatctgctg ccatcttatc
    19501 tatctcatca aataagaata caggattttt tgtttgggct tcttttaccc cattaattat
    19561 tcttcctgga attgaaccta cataagttct tctatgacct cttatttctg cttcatctct
    19621 aactccaccc aaagatattc ttacaaattt tctatttaat gctctggcga ttgattttac
    19681 tatagatgtc tttcctgttc ctggaggacc aactagacat attataggcc ctttaagtga
    19741 cttagcaaga gttcttatag ctagatactc tagtattctc tccttaactt tttctaatcc
    19801 ataatggtct tcatctaata tatcttttgc cttagttata tctaatttat cttttgtctc
    19861 tttattccat ggcaatgaga atatagtatc taaatagttt ctacttacag atacatctgg
    19921 agacatagaa gatatttttg aaaatttatc tatctctttt tctatttttt ctttggttgt
    19981 cttaggtgct tttatttttt taagcttttc tctatactca tctgcttcag aatttatatc
    20041 ttcttcttca cctaattctt tctgtatagc ttttaattgt tctctaagat aatattcttt
    20101 ttgaacctta ttcatctgtt tttttactct taaagttatt ttcttttcta tttttaatat
    20161 atctatttcc tctaataata tagaataaat aagttcaagt ctttttctaa tatcaaattc
    20221 ttctaatatt tcttgttttt ggcttgattt tagatatatg tttgcagcta tcgtatctat
    20281 aaatctatct acatcttcta tatcagctaa agatattaat atttctggtg ataccctatt
    20341 tccaatattt atatactctt caaaggcatc aaatacattt cttacaaatg cttcaatttc
    20401 aacttctgtt tcactatcca aattatcact attaaatact atttcttcta ttactgctct
    20461 gaaataccca tcttcttgtt ctattttctt tactctaccc cttgatacac cttcaaccaa
    20521 aacacgaact gtatctcctg gtaattttat catttgctta actttacaga ttgttcccac
    20581 atgataaaaa tcctcttctc ctggctcatc tacctctgct tctttctgag aagttaaaaa
    20641 tataagttct tcatccatca tagcttggtc taaagcttta agagatatct ctctacctat
    20701 atcaaaattt aatatcatat atggaaatat agctaatcct cttagaggaa ttaatggtaa
    20761 ttcatgatct attttagtat aattttgttc catcaacatt actccttttc tagtctaatt
    20821 gctttgcttt taatattata tatttgaaca agttaatttt caacattaat gataaattct
    20881 tagaatacta tcatactata ttatcttttt attatgatat aatattaata ttagtatact
    20941 tagatgttat ttatcttttg gaggtttcta ttatgttgaa attgttttta acctttttaa
    21001 aaattggtgc gtttacattt ggtggtggat acgctatggt tcctcttata caagatgaac
    21061 ttgtaaacaa acaaaaactt ttagagcagg aagaatttat tgattattta tccatagctc
    21121 aaagttatcc tggagtactg gcagttaata tatctgtatt attaggatat aaactttatg
    21181 gtataccagg agttcttata tgtaccttag gctctgcttt accatcattt tgtatagtct
    21241 tagtcttatc gtatctatac tttaaaaatt catcatctaa aattttagat ggatttttta
    21301 aaggagttgc gcctgttgta atagctctta tattgtattc ttttacgagc atgttcaaga
    21361 aactaccaaa gtctaaaact aacatactac tattaattat agcagtttta tctgttggtg
    21421 tattcaatat aagccctatt tatttaataa ttggaggagg tgtatatagt ctatgtcaga
    21481 aataatacta ctcttcttaa tattccttaa aataggggca tttagttttg gtggcggtta
    21541 tgccatgcta ccatttatcc agcaagaatt tatatctaaa tatcacttta taactaatca
    21601 agagtttttg gatttacttg ctatatcaca atctacacca ggtcctgtag caataaatag
    21661 tgctacattt gtaggattta agactgctgg cttctttggt tctctagctg caactattgg
    21721 tgttacaatt tttgcattaa taggtctaac tattatatca aagttatttt ctaaatttaa
    21781 aaataataaa aaggtagaaa acttattgac agttcttaga ccaattactc taggattcat
    21841 attatcagca gctttttcat ctgccaaaga agttaattgg gatttatatg gaataattgc
    21901 atttatagca tcattttatc ttttatataa aggaaaaatt ggttccattg caattgtatt
    21961 cgtctttggt attctaggta tattactcac atttttatga taatgatacc tattttatat
    22021 ttagcatatt aacataaaaa aaggagcttt taaagctcct tttcatcatc ttatgcactt
    22081 tcctcttgat ccttaagtac tatgatagga tttactgagt cttcgttcac agatttctct
    22141 gttactataa ccttctttat attatctcta gatggtactt caaacatagt ttccatcatt
    22201 acgctttcaa ctatacttct aagtcctcta gctcctgtat ttctttctat agccttttta
    22261 gcgattgcac gaagagcacc ttcttcaaat tctagctcaa catcatctaa ctccaataac
    22321 tttttatact gttttactag agcattttta ggttcctgta atatctgcat taatgcatct
    22381 tcatccaaca actctaaagt agctaaaact ggtattcttc ctataaactc tggtattata
    22441 ccatatttta ataaatcctc tggaagtact ttttcataca gcttccctaa atctaattct
    22501 tttttacttt ctattttagc tccaaaacct agtgttttat ctccaccacg tttttgaatt
    22561 atcttctcta atccatcaaa agctccacct aatataaata atacattagt agtatctatc
    22621 tttaaaaatt cttgatgggg atgttttctt cctccttgtg gtggaacatt tgcaacagta
    22681 ccttctaata tttttagaag tgcttgttga acaccttcac cactaacatc tctagttata
    22741 gatgggtttt cagattttct tgcaatctta tctatctcat ctatatatat tatacctctt
    22801 tcagcttttt ctatatcaaa atcagcagct tgaataagtt ttaaaagtat attttcaacg
    22861 tcttctccaa catatccagc ttcagtcaat gatgtagcat ctgccattgc aaaaggtaca
    22921 tttagagttc ttgctagagt ttgagcaagt aatgtctttc cagaacctgt aggtcctaat
    22981 aaaagtatat tactcttttg aatttctata tccttactac tagatttttt actgtatatt
    23041 ctcttataat gattataaac cgcaactgat aaagcttttt tagctttttc ttgacctatt
    23101 acataatcat ttagaatctc catcatttcc tttggttttg gtaaagatgt agtatcttca
    23161 tctatagtat cttctatttc ttcctgaata atttcgtcac aaagttcaac acactcgtca
    23221 caaatatata catttggacc tgcaattaat cttcttactt gatcttgatt tttaccgcag
    23281 aatgaacact ttaattgtcg tttttcttca tatttagaca tattaacacc tctctctatc
    23341 tacggtctct ttgtaaatac ttcatctatt aaaccatatt ctttggcttc tagtgcactc
    23401 atgaagttat cacgttcagt atccatttta attttttcta atggctgacc agttctttca
    23461 gataatatct catttaaagt ttcttttatt tttaaaattc tctttgcatg aatttctata
    23521 tctgttgctt gaccttgagc tccacctaat ggttgatgta tcattatttc actatttggt
    23581 agtgctagtc tttttccttt tgctcctgct gccaacaaga atgctcccat agaagcagcc
    23641 atacctatac atatagtact tacatctggt ttgatgtatt gcatagtatc atatatagcc
    23701 attccagaag ttatacttcc tcctggagaa tttatatata aatgtatatc tttgtctggg
    23761 tcttcagctt ctaaaaataa tagctgtgct actataagcc ctgctgtggc atcgttaact
    23821 tgatctccta agaagattat tctgtctttt aatagtctag aaaaaatatc ataagatctt
    23881 tctcctcttc ctgtttgttc aacaactaca ggtactaatg ccatggtttc ataccccctt
    23941 tattctatat aatttacagt agctttttta agctactgta aattattata cgcatttaac
    24001 taaattatat ttgcacatca ttatatacta aacatttcat aacgtcaact atattagtta
    24061 gcgtttattt tattaagcta ttgttgcatt atcaactaat aaatctattg tttttcttat
    24121 ttttatttga ccttttatat cttctttgtc agcatctctt aaagaagctt ctattttttc
    24181 tacttccata ttgtaagcag aagccatttt ttctaactca gccttaaatt cttcttctgt
    24241 tgcttcaatt ccttcagctt tagttattgc ttctaatact aaagaagact taactaattt
    24301 tttagcatct tcttttctct cttctcttaa ttcttccata gttctaccag tcatctctag
    24361 taattgttgt aatccaaatc cttgatattg taattggtag ttaagttcat ttaacatatt
    24421 atctatttga tgttgtatca taacttctgg tatttctatt tctgtatttt cagcaacttt
    24481 ttctactact gaatttctag tttctgcatc tgctctattt ttagcttctt cttctaactt
    24541 agctcttaca tctgctttta attcatctaa agaatcaaat tcactagtat ctttagcaaa
    24601 ttcatcatca agtgcagata attcttttac ttttacatca tttattttta cattaaatac
    24661 aactggtttt ccagctaaat cttgtgagtg atattcttct gggaaagtaa cattaacttc
    24721 tacttcttca ccagcttttt tacctactaa ttgttcttca aatcctggta taaatgtgtt
    24781 tgaacctata actaagttat aattttcacc tttaccacca tcaaaagcta caccattttc
    24841 aaaaccttcg aagtctatta tagctgtatc tccatcttct aaagctttgt cttctacact
    24901 tactaatctg gcattttttt caaccatttc ttgtagttta gcatcaacat tttcgtcact
    24961 tacagtattc tcaaccttag ctatttctat acccttgtag tttcctaatt caaactctgg
    25021 tttaacttct acattaagaa ccataaccaa cccattatct ttacttattt cttctatatc
    25081 taaatctgga ttgtctattg ggtctatgtc taattccttg atagcttctg gataaacttc
    25141 tgggaataat atttctatag catcattgta gaatatacct tttccatatt gagtctctat
    25201 aacaattctt ggagctttac cttttctaaa tccaggtata ttgtatttat ttctgctttt
    25261 attataagcc ttatttactg ctgcttcaaa tttattgtta tctactgtta tttttaaagt
    25321 aactttatta ccctcttttt taattagttc tgctttcatc cttctaatcc tcctagtgat
    25381 atttatgtaa tacccgataa cggtattata attcattcta tttataattc aaccacttaa
    25441 ttatatcaca taagtttttt tatttacaag tgttccatta atatcgttgt acttatttga
    25501 taaaatttaa ttttttgagc gttttttgcc atttttttag ataaatacac ctttatatgc
    25561 gtatttcttc aatttttatg tcatcttctt ctatatccat aatgacaaaa cttttatacg
    25621 atactcctct tggaagtgaa gtgcttccag gatttatgta aagtacacca tctttaattt
    25681 ctctaaatgg ggtatgggta tggccaaata taactatatc agcatcaact tcagttgcct
    25741 ttttttctaa catattagtt ccatatttta caccatactt atctccatgg cataagaata
    25801 tggttttatt tgccacttca aagacaactt cttcctcaac agcatcaaag tcacaattac
    25861 ctttaactgc aataatacct acattagtca tgctatgaat atatcttgaa tcagtaaagt
    25921 tatctcctgc atgaattatt aggtcacatt ctttcaaata tggtattgtt ttttccatat
    25981 ttttaatcat catatgtgtg tcgcttacta tgcctatttt cattacttca ctatcctttt
    26041 tataaactct tgtttcataa gttttagtgc gtttgctcta tgactgattg aattttttat
    26101 aacactaggt atttcaccaa aagtcttatc atatcctttt actataaata agctatcata
    26161 tccaaaacca tttttacctt tttcttcaaa tcctatcatt ccttcacaaa ttcctcttac
    26221 tacaaattct tttccatcag gaaaaactac tgctattgca gagacgaatc ttgcatttct
    26281 tttgctcatt ggtacatttt gcatagcttt taacagtttt tttctatttt cttcatctgt
    26341 tgcatgttct cctgcatatc tagctgaata aacaccaggt tttttgccta aagcatctac
    26401 ttctaagcca gaatcatctg atattgctat aagtttagtc ttttttgcta ttgctctagc
    26461 ttttatcaac gcattatgct caaatgtttt tccatcttct actatctcta tacctgctaa
    26521 atcaacatct tttaaagagt acactttata ttcaaaatct tttaagattt cacctatttc
    26581 ttctagctta tgagcattat tagtagcaat cactacttca ttaccataat ccatacccaa
    26641 tatctcatct gctatttcac ctaaagcttc tctttgaagc cttattaatt ctttattccc
    26701 tttttcacct aactctaaca ataaatttaa atctgctctt gaaaaaggtt tctcttctcc
    26761 tgtcccctgt acttctacaa actcacactt atcagtcatt attatattca tatctacctg
    26821 tgctttagaa tcttcttcat aacataaatc tagcatgtgt attccattta caataccaac
    26881 actaattgca gatacaaaat ttgttattgg catctctttt attgtctttg ctttatataa
    26941 tttatatatt gcttctgcaa ctgctacaaa tgcccctgtt atagatgcag ttctagttcc
    27001 accatctgcc tgaatcacat cacaatctac ccaaatagtt ctttctccta atttattcaa
    27061 gtctacaaca gaccttattg ctcttcctat taacctctgt atttcttgtg ttcttccatc
    27121 aatttttccc ctagatgcat ctcttatctt tctttgttgt gttgctcttg gtagcataga
    27181 atattcagca tttatccatc cagtaccact atttcttaaa aaaggaggaa ctttttcttc
    27241 cactgatgca gtgcatataa cctttgtctc tcccatttct ataagaacag aaccttctgc
    27301 atactttgta taatctctag ttatctttac aggtcttatc tgttcgttac ttctatcata
    27361 acttctggtc attttttata tcctttctca tattttttat tttttataaa tttattttta
    27421 tagtttttaa ttttgtcaaa tattaattat tgtcattttt cgtaatctta ttagcttact
    27481 gaactattct atcattaatt atagtagttt tctactaaat taagcgactt tttaactctc
    27541 taatacagct tttacttcat ctttcgatga taactttaat aattctaaaa atctctcttc
    27601 atctataact ttaattccta aatcatttgc tttagtaagt ttagaaccag cttcttcacc
    27661 tgccaaaaca aatgttgtcg atttactaac actagatgta gcttttccac ctcttttttc
    27721 tatcatatct ttcgcatcat ttctttttaa tgtagtaagt gtaccagtca atacgatttt
    27781 catcccttca aatatttttt ctactttttc acctgtatta tccaatgatt ttgtatttac
    27841 tcctacattt tttaacttgt ttataacgtt catatttttg tcttccttaa aaaactcgac
    27901 aacgctgttt gccattatac ttccaaattc ctctaattct tctagttgct cactagttgc
    27961 agaaattact tcatctaaat ccttaaagtt atatgcaagt atcttagctg ctttaactcc
    28021 tataaattta atacctaatc catttataag tctccataaa tcattttctt ttgatttttc
    28081 aattgaattt attaaattgt cagcagattt ttcgcccatt ctctctaggt cgactacatc
    28141 ttcctttttt atataatata aatcagatac atcttgaata attttttcat ttaatagcag
    28201 tgtaattata gattctccca atccatctat attcattgca tcccttgaca caaagtgtat
    28261 aattcccctt cttatttggg ctgggcaaga catattgata cattttacag cagcctctcc
    28321 ttctaatctt attgttggct ctgaacaaac tggacacttt tctggcattt taaaatctat
    28381 ttcatctcca gtacgttcct cttttataac ttctaaaact tgaggtatta tgtcccctgc
    28441 tttttgaact aatactgtat catttatttt tatatctttt tctcttatat aatcttcatt
    28501 gtgaagtgta gctctactta cagtagtacc tgcaagtctg actggttcaa gaattgctga
    28561 aggtgttatt gtaccagttc tcccaacttc tactattata tctactattt tagttttctt
    28621 cttttctgct gggaatttat atgcaattgc ccatctagga cttttggctg tatatcccat
    28681 ttcgtctctt tgttttatat tgtttacttt tattaccata ccatctattt cgtagtctaa
    28741 attacccctg ttatctgtcc agtattcaat atgctcaata acttcatcta tacttttaca
    28801 aactttataa ctctgactta ctgaaaatcc tagtttttct aagtactcta gtgattcact
    28861 gtgactttct aaatcatatt cttctatatt ttccatatta aatacaaata tatctaatgg
    28921 tctctttgct gttagttttg ggtctaattg tctcaatgaa ccagctgcaa gattccttgg
    28981 attagcaaat aatggctgtt cttgttcttc ttgttgttca tttacttttc taaaattatc
    29041 ttttgatata tatacttctc ctctaactat tagttctttt ttatcattta tcttaagagg
    29101 tatgcttttt actgtcatta agttttgaga aatatcttct cctacaactc catctcctct
    29161 agttgctcct ttttcaaact ctccattgtt ataagttaga cctacagaaa gaccatctat
    29221 tttaaattca acaacatatt caacattttc tcccacatat tcttgaactc tcttatcaaa
    29281 atctctcaaa tcttgctctg aaaaagcatt tgataaactc aacataggag ttttatgtac
    29341 aatttgattg aatttatcta atggcttacc tcctacccta tttgttggag aatcaattct
    29401 ctttagttct ggatgttctt cttctaaaga aattaactcc ttcattaact tatcgtattc
    29461 ataatctgat atttctgggc tatcttgatt ataatacctt tcattatggt agtttattgt
    29521 ctctataagt ttattaattt catcttttac gctcactttt tgcacctctt catattttta
    29581 aaattaaatt attttgaaat ttccctataa ttaattatct cctatttata tattttttag
    29641 tatatcactt ttttgacttt aaatttatta caaaaaaaac tcttattagt atctttaata
    29701 cgactaataa gagtttttat ttttatcaaa attttttatt tttaatagcc tcttgatatg
    29761 tctacaacat tatctacagg tttattctcc attatatagt gtttcaaatt attataaacc
    29821 atattaaatg ttctctcttt gtttttatct gacacccaag aattatgagg agttactatg
    29881 acattttcgc actcccacaa cttattgtcc ttgtttaaag gttcactttc aaatacgtct
    29941 agtgctaccc ctctaaattt ctctacacat tcttctaaat ctttctgatt aactgtattt
    30001 cctctaccta catttataaa tacagaacca tctttcataa gtttaaacat atctttgttt
    30061 actattccat ctgtactttt tgtagaaggc attgctacaa ctactatatc acattcttca
    30121 aatacaatat tcatatcttc agtagcaaaa cacttatcaa agtatttttt actacttcca
    30181 tcagtattga caccccatat ttctacacca aaagctttta atcgttttgc tgcttctgaa
    30241 gatatagtac ctgttcctaa aaatccaact ctttgtccat acaattctga tacagaaaaa
    30301 tccatcttcc attctttatt ttgttgttgt ttaaaaaatt ttgcactatt tttatatatt
    30361 tctaaaatat acaatacaat actttcacca ataggtacac tatatccgcc tctattatta
    30421 gctatcttaa tatttctctt caatacctct tcttttggaa gttggtctat acctacacta
    30481 gttgtctgta tatattgtaa atttttcatc ttaaaaatat ctaatctctc aaatggattg
    30541 tatgtaacta gtacatctgc tgtatttaca tcctcattat tttcaatact atcttcagag
    30601 taatgtatga catcatagcc taattctctt attttatcaa atttttcttt tccataattt
    30661 attgtaaata aaactttcat ctcaaatctc ctccatctac ccacatttaa aattttatat
    30721 tctaaaatat aatatgatac tcaatgtaca ttagttaaaa ttactataag atatcttaaa
    30781 tttacttatg ttcaattgtt tttcctaaag acatagcatt acgttcttga actaaatttt
    30841 ctattaaatt attcaatgtc caatcaatag atgtctctgt taccatagct gtaaaaggtc
    30901 tatttattct cacttttttt agcccttcta aaaatgcatt tacttgtgtg cttggagtgt
    30961 tattaaatat tacagactta ctcttaatcc cattttcaca ttcacttgat atatttccat
    31021 ctaaaatgtc tcttattata ttctctccgt ttctttcact taagattata tggtctctta
    31081 ttccagcaaa gttacttacg tttttaatta atgataattc ttttttatta aagtttacaa
    31141 gcataataca cttcctattg tgtattttat ctaggttatt attatttatt ttttcaaatg
    31201 acattttatc catcctttca tttatttata tactttaatt taccccatac atttaaaata
    31261 atcaattttt atagttaatt tttatattaa tacccaaatt atatttaaat agttaggcta
    31321 tccaaaacta atatataaaa ttagaataat tagattaata tctacaaatc ataacctaaa
    31381 ggagagatac catgaataca ttactaaaca ataaatttag cattaaaaac ttttcaaatg
    31441 cttgggttat agtacttggt tgtatgttaa tacaagctgt tccatttagt attgtagcaa
    31501 gtatacagcc tcaatttata agttatgttg tagaaggaga aggctttagt ttagcttctt
    31561 tttctctaat attcactatt ggtactattg cctcagcaat tgcatcacct tttataggtg
    31621 tattattttc taaagtcaat attaagatac tatatttatt aggttgtata atttctagta
    31681 ttgcttttgc tactttttct atatgtactg aactatggca attttacact gtatcatgta
    31741 ttgttcaaat tggcgctaca attatatctg ctataggaat acctgtttta ataagtgctt
    31801 ggtttgatga agaaagcaaa ggaaaagctt tgggctttgc ttttgctggt ggttctattg
    31861 gtagtatatt tctacaacca cttgcagttc gcttattagc aactcaagga tacagtcatt
    31921 cttatctaat atttggaatt atagcattaa tagttggtat acctgtaata ttattcatac
    31981 tcaggatgcc taaagatatt aatgaaaagg taaaatctaa aggtaaaaaa gagaaagcat
    32041 ctgatacaat ttctccttca gtatggggtt atacattaaa agaagctaaa aaaattaaat
    32101 atttttggat tatgactatt ggatttatat ttgttggtat atatgtttca tcattatccg
    32161 tacaatatcc aacttatctt agaaattatc taaatcctat tctaatagga acagtaggct
    32221 ccacatttgc tttatttgct ctcattggta atttatttgg aggattattg tttgataaat
    32281 tcggtcaaac aaagccactt attatatctt ttgtattggt tcttatagca actttatcat
    32341 tactattggt agataaatct tctacttttg catttgtatt tgccattttg aaaggtcttt
    32401 ctgtatttgc ttatatgatt ggtcctgctt atttaactgg ctctttcttt ggtcaaaagg
    32461 agtttggtag catatatgga atcgtacaat taatttttgc agtgggattt gcattaggtt
    32521 caacattatt tggattgtta gttgataatt ttggatacag attttcttgg tctattataa
    32581 ttttatcagt tataattgcc tatactttac ttattataac ttctatagga atgaaaaaat
    32641 tgaataaaga aagattagat aaactaatgc aataattgat ttttagatat ataaatatta
    32701 taataaaaaa gatggagctt ttaatcataa ataaaactcc atctttttta tattacaata
    32761 tagctaattt tctcttattt ttaactttac tatctatatc ctcatcctta actatagtaa
    32821 atgccttagt tggacaaaca tttacacatg caggcccttc tggcgattct atacaaaaat
    32881 cacacttatt tgctgtcatt ctttctctaa agcaaagctt tccttcatct acatctttta
    32941 atgtaactat gtctattgca cctataggac atgctaacat acaagtctta catcctatac
    33001 aattttcttc atttattttt attgtgttcc caaccctaac tataccacca tttggacatg
    33061 cctttgcaca aggagcatct tcacaatgtc tacactgtat tggagcactt acttcttttg
    33121 tctttatgac agaaagtttt ggattaaaat ttatttcatc tggattttgg taaaaaatat
    33181 cttcatctga atgtgcaact acacatccta tcatacaagt tctacatcct atgcatttat
    33241 cagggtctgc tataacaaaa tagttcatca cttagccact tcctttccta tacaatatgt
    33301 agtgtgtaat agatgatgag atttttctcc taatggttct accagatatt catcatacag
    33361 ttttttaata tcaggattct catgagattt tctaattgct aaatgttcat catgcacgta
    33421 tgttgctttt gttctatttt cataagccaa ttccttatat tcttctagta aaatttttgg
    33481 ttgacctcca ccacttacac acccaacagg acaagtcata acttcaataa aatctacatc
    33541 taattttcct ttttccaagt cttcaagcac tggtattaca ttttttaatc cacttactac
    33601 tccaactctt aagtctaagt ctcctatttt aatagttgac tttctaaaac cattttctcc
    33661 tcttacttgt tttacttcta catcaggaat actttctcca gttataatct catatcctgt
    33721 tcttatagca gcttccataa ccccaccagt aacaccaaag atagttccag ctccactata
    33781 actacctaaa ggactatcaa atttttcttc tcttaaattt ttaaaatcaa ttcccatgtc
    33841 ttttattaaa taagctagtt ctctagtagt taatactaca tctacatctc tatatccact
    33901 agaatccatt tcttctctat cacattcata ttttttacat gtacatggca ttatagaaac
    33961 actaaatatc tttgatgcat ctacattatt tatctctgca ccataagttt taaatattgc
    34021 accacccatc tgctgaggtg atttacaaga agataaatga ttagttaatt taggataatt
    34081 tttttccatg aattttaccc aagctggaca acaagatgta aacattggaa gagttccacc
    34141 ttctgtcact cttttaatta attcactacc ttcttccatt atagttaaat ctgctgcaaa
    34201 attagtatcg tagactctat caaaatttaa agctctaagt gctgctgcca tttttccagc
    34261 acctaagtat cctaaataat atccgaaatc ttctcctaaa gcaactctaa ctgctggtgc
    34321 acattggacc atagtgaata catttgggtc acttaaagct ttctttacct tatctatatc
    34381 acatacattg tatgctgcaa atataggttc atttatagac tctggtatct ctctttcttg
    34441 ttttttctct tgtaaaaact caaagccttc atctataact gaggcataag atttacaagt
    34501 ttgaacacat tgaccgcaca taacacatct atctaaattt atctcttgtg gctttccatc
    34561 ttcaccttca atagcattta ctggacagac ctttgaacat tctctacatc cagtacataa
    34621 atccttatct atatttatta tcataaacgt cacctacccc tgtatccttt atttatttgt
    34681 taacaataaa ctaagtgcag cttgtctatt cttagctttt ttgtcatcta ttggagtaac
    34741 aagttttaat gcttcctgag gacatgcact tatacaagct attttttcat tgtctttaca
    34801 taagtcacat ttataagcta tcttcttatt ttcatctaaa attacttgtt ctacttcttt
    34861 accatcttca tattgtggaa gtaagtctat agctccaaaa ggacatgcta gcagacaagt
    34921 tttacatcct atacactttt cttcatttac agacataata ttgttttctt tgactatagc
    34981 tttttgtgga catgagttta aacaaggagc atcttcacaa tgtctacact gtattggcat
    35041 acagaaattg tcacctttta ctaaataaag tctaggtata acaggtatat caactgttcc
    35101 aactgtataa cccacattat tatgctgatt atgcattgta aaacaagcta cttcacaagc
    35161 tctacaacct gtacatttgt ttgggtccgc tattacaaaa gagcctattt tatttttcat
    35221 attatcccac ctttcaattt gtatatttcc aaccctctag ttactttcat catatgtcta
    35281 cttactttca tcatatatat ttatatattt cactattttc tcagtactta tatttcgttt
    35341 acattttttg cacaaattgt atgtgttatt atacacctta tcagtatcgt caattaatac
    35401 tccacagatt tcacactttg aacatttttg ttcttctttt ttagtacaca tatacttatt
    35461 ctcacttttt gataactctc tgtggatttg cataaatatt catccgtctt cctcttacaa
    35521 atccaataag cgttatattt aattttttag aaagctctat tgataaatta gtcggtgctg
    35581 attttgatac tacaatagga atttgagtca tagctgcttt taatatcatt tccaatgata
    35641 ttcttccact tacagccaca attttatctt ttaatgttat gtcatttaaa acacaaaatc
    35701 caatagcctt atccattgca ttatgccttg ctacatcttc acaagtgact atttttttat
    35761 caaaattaaa tacagatacg ctatgtaccc caccagtatt tttaaataat tctgatgaat
    35821 ttaaatttct atccattata ctgtaaatcg tatcataatt tatttttata ttgctcttta
    35881 cagaagcaca tgttatatag tctagtgaat ttaaaaatat aatttgctca tcttgatttt
    35941 tttgtttctc ttgaatagtt acttttgcaa aacgttcact ctcatttatc tcaaatttta
    36001 ataagctttt tttgttttct atgtatcctt ttgttttcaa gaatcctact ataagttcct
    36061 ctaaattata tggggtacat aaaaatgtat ttacatattt atcatttaaa ataaaactaa
    36121 gtggatattc tgcaattatt tcttcattat ctattgatac ttcatgttca tttattttgc
    36181 ttacttctac attaaaagaa tttaaatatt tgtagtccac tagactataa ctattttcaa
    36241 aaactttatc cttactattt tcttgtaatt tagtttttga gtatatattg ttcataaaat
    36301 attagccttt ctgcctttta taaatcttaa atctaataaa tcattagata tttgtagctg
    36361 tcattttgtc tttcaaactt tgatactctt ctcttacaca tttttctgct aattcttggt
    36421 cttcaagttt ttcaagttta acagcacaat atttatactc tggtgtttta gatatagggt
    36481 ctaaatttgc tattgtaagt tcattgcaag ctccaaccca ccactgataa gtcatatatg
    36541 ttgcaccttc cttaactcta tcagtaactg ttgctcttgt tattacactt cctcttcttg
    36601 aactaattct aactaattca tcatcttcaa ttcctaattt ttcagcatca ttagaattta
    36661 tttgaacacg tcctggttca tcttctaatg aactaagtgt tctacaatta ccagtcattg
    36721 ttcttactga atagtgtcca acttctctta cagtacataa actaaatggg tattcatcat
    36781 cttcaacttc catagggggt ctccattcag cagcgaacaa attaccttta ccattaggag
    36841 tagaaaactt ttgaccttca tacagataca tagttccttt atcttccata ctttcactct
    36901 tacaaggcca ttgaacgcat ccttgagttt ctatcttttc ataagtagca cctaagaaac
    36961 ttggacataa ttgtctaagt tcgtcccata tttccttagt atttttataa ttcataggat
    37021 atcccattgc tgtagaaatt tcgcttataa tttgccagtc tggttttaca tctccttgtg
    37081 gctctatagc ttttctcatc aattggaatc ctctatctgc acatgtatat actccctcat
    37141 gttctcccca agaagtagct ggaagtataa catcagcgtg aagtgctgtc ttattcataa
    37201 atatatcttg aacaatgaca aattccaatt catctaatgc ttctctaact tctgatgcat
    37261 ctgggtcact ttgcactggg tcttctccaa atatataata agctttaagc tttttctctt
    37321 ttagtactaa gtctggaact tgagttaaac tataaccatt attaggagat aattttaccc
    37381 cccaagcttt ttcaaacttt tctcttatct tatcatcagt tacattttga tagccaggat
    37441 atacattagg aagagctccc atatcacaag ctccttgaac attattttgt ccacgtacag
    37501 gtcctattcc aacgctttct ctaccaaaat tacctgtaag tagagcaatt gatgcaagtc
    37561 ccttaactac atcaacagct tgaccaaatt gacagacacc cattccataa agtatcatag
    37621 cttttttacc ttttgcatat tctctcatag cttttcttat aagctcttct gggattcctg
    37681 taatcttttc agcatattta gctgtatatg gtttaacaat ttctttatac tcatcaaatc
    37741 cttgtgtatg attttgaaca aattctttat tgtaaagacc ttcttctatt aatacatttc
    37801 caaaagcatt tactaaaacc atgtttgttc caccttttat aggtagatgt atatcagcaa
    37861 ttcttgcaga ttcagttact ctagggtcag taacaattaa tttagcacca ttttttttag
    37921 cttttactat tctatttgcc actattggat gtgaatctgc tccattatat ccaaatataa
    37981 ataaaacatc tgcattttct atctctggta tagaattaga cattgcacca ctacctaatg
    38041 agtaagccag accggctaca gatggtgcat gtcagacacg agcacaatgg tcaacattat
    38101 tagttcctat tgtagctctc ataaattttt gcattatata gtttgcttca ttaccaggtc
    38161 ctcttgcaga acctgttccc ataatagaat caggtccata tttttcttta atttcattta
    38221 gtcttgaagc tgtatagttt atagcctcat cccattcaac ctcttctagt acaccttgtt
    38281 ttcttatcat tggctttttt agcctaggtg ttagaatttt agggtcattt agaaaatccc
    38341 atccataacg accttttaaa cacaaacttt cttgatttgt tctaccatta gccggttcag
    38401 ctcttaatat cttattatct tttactacta gatataattg gcatccagct ccacagtatg
    38461 gacaaactgt taaaattttt ttctccatac aattcccccc ttagatttat cccctgataa
    38521 gtaaaattta tcttaaagat aatgagtgtt tttataatat gcaaaatcat aaatattttg
    38581 caatactatc tattaaattc aacaattttc tcacaattcc tcttaaattt caaaaaaaat
    38641 atgtcataat aatctttata tttcaaccat ttaattaaaa tattctagtt cttatgacat
    38701 attttttaat atactcaata tatattcttt aaacttattt agttttcact taaaacaata
    38761 tttctgccaa ttctattttt cattctatag tgagtaatta cagtaaatat tccacttcca
    38821 atcagaatca aatagtacat aaatccacca tataaaaata ctgcatatcc catcaaaggt
    38881 tgagggaata ctgatttgaa tatagtgaaa aaggctaatt cattagctcc tacattccca
    38941 ggtgttggta ttggagatat tgccatatat aaaaatgctt gtaatgtcag tatataaata
    39001 tagctataac cttgtaaatt aaatgcttta tatatccaaa atgaaacact aaagtaagca
    39061 cttaattgaa taaaagttac tattatagtt gaaattaata cctttttatt ctttgcaaaa
    39121 aaatttattg ctttactata atcatctata aaactttcta tggattcaat cttattatct
    39181 aaaaatttta aaaacttaat ttttgataaa tgctttatag taattctcat aaaatatttt
    39241 atttttttag gatttaaaat aactaatatt atcataatta agacaaatga attaatggct
    39301 atccctagaa acactagagg cataatcatt ttcatttgtt tttctaacat agcaaaattc
    39361 attaaaacaa gtattgtaca ataaaaagta actactattt ggaagataat agacttattg
    39421 gtaacaactg cacttgcctt actaagtggc attttacatt ttttaagtac atatatctgt
    39481 actggttggc ttcctgaagc aaaaggagtt attaaattat aataaaatcc cataatggct
    39541 agcttaaaac caataaatct aatattaact ttgtgagtgc tttctataat tatcttcatt
    39601 actactcctt caagcattat gtggcacatt attgccaaag cacctatgaa taaaaacttc
    39661 ttatctacca taaccataac atttgatagc attttaatat ccaatgtttt aaacactagg
    39721 taaattgtta tacctattaa caaaaataaa aatgtatact gtaataaact ctttctaata
    39781 ttctttagtc tatccattag aaataaccat cctttgctca agatttatac taaatactat
    39841 attattagta tacactatga atcttaatat tttataacaa aataccttac aattttgtca
    39901 tttacaaaaa atattaatct ataaattaaa ttttaatata tagattaata ttttacaaac
    39961 attttgtaga tatatataat attttcacta agtaacactt atacttatta cacccattta
    40021 taccctatcc cccatacagt ttctattgta taaatatcat attgttttaa tttgcttcgt
    40081 atatttttta tatgctctgt gatagtactt atatcacttt ctccatcaaa accatatacc
    40141 gactcatata ttctttcttt tgaaaatact tgtcccttat tttttgctag aaattcacat
    40201 attagatatt cacttttagt aaaattaatt tttttaccat caattgaaac ttctttgcct
    40261 aaaaagttaa attgaacatt tgagatagtt aataaattct ttttttctct actttctcgc
    40321 cttaaatgag cagttatcct agcccttaat tctcctacac caaaaggttt ggttatatag
    40381 tcatctgcac ctatgccaag accgtacata atatcacttt ccatattttt tgctgtcaaa
    40441 aacagtattg gacaatcaac cttatttctt atagttttac atacttcaaa accatccatc
    40501 ttaggcatca taacatctaa tattattaga ttaaaataat taaaatccat gttcatagcc
    40561 ttttctacat cactaattac ctttacttca tgtccatctc ttttcaacac attttcaatc
    40621 aactttaaca tatctaactc atcatctact actaatatct tagacataat aactcctcca
    40681 tttatccgtt taatagtatt ctaatttata tctttaataa tatctttaaa attcacatta
    40741 accataatac tctcatatta tagcttacaa taattaatta ctattttaca aataaaatat
    40801 tttagataca aaaactttat atttcaaaaa ctttatattc attttacacg catttactta
    40861 aatataaaaa tttatttaac aatttattat tgtaatattt tgaatatata ataaaattaa
    40921 taataagaaa actttttata aatacacttt taattgttta aattggagga aaaaattatg
    40981 gatgaaaata taacaaaaaa taattataat gttccatttg actatgttcg aaaaaaactc
    41041 aaagaattag accctcatac aattagtaat ttaagtaata tacctttcaa taatgattta
    41101 aatagattca cactcaattt ttttgataga caatatatta tagactatcc aagtggagaa
    41161 gtttggaata gtaatggtag cctttgcaat aactttgagc ttaaaatctt gatagttaga
    41221 tatttaatca atgctaaagg tatccctaga actaataaat atgtaacttt taaagaaata
    41281 ccaggaggca atgtttatta tccaaatttt ttaaacagga ctctatatag gctttcagaa
    41341 gtttttacat ctcaaataga caaatataag ttagttatgg agaaaattgg agctgaaaaa
    41401 gtaaacatgg gagatttagc ttataggttt acatatatgg gtaatacatc tatgatattt
    41461 atactttggt ttggagatga tgaatttcct ccaaattcaa atatattatt tgattctaat
    41521 atagtttatt acttcaatgc agaagattta gcagttgttc ctgatacagc tataaatgca
    41581 attttaaata aaataaatca attataaata taaataatat tataataaag tttttgatag
    41641 atttaataga atataatatg aaatggggta aaaaatgaat gtagaaaatc aatctttatc
    41701 agatattgaa ataatattat cacacaggta tgataatggt gcagactatt ggactacacc
    41761 tgataagcgt ttaataaaag gttctccttt ctctactctt gatagtgtac tttatctatt
    41821 agagttaggt gtgaaccctg atgatacttt acttaaagaa tgtgctgact tgatatttag
    41881 cacatggcga gaagatggac gtttcaaact atatccaaat ggaggtattt acccttgtca
    41941 tactgcaaat gctgctaacg tactctgtca tatgggatat gcatctgaca ttagaatgca
    42001 aaaaacgttt caacattttt tagatacaca gtatactgat ggtgggtggc gttgcaataa
    42061 atttagtttt ggtcgaggtc cagaaactga atactcaaat ccactaccaa ctcttaatat
    42121 attaaatgca ttccgtttta gtaattatct aaataaagaa tcaaaacttg acaaagctgt
    42181 agattttcta cttgaccatt ggactattaa aaaaccactc ggcccttgtc actatggaat
    42241 tggcacatta tttatgcaag ttgaatatcc tttccgtaat tataacctat tcctttatgt
    42301 ctacgtttta tcattttata atcgtgcaaa aaaggataag agatttttag aagcattgaa
    42361 gatacttgaa tctaaaatga taggtaataa aattgtcgtt gaacgtgtag ttccaaaact
    42421 atctaaatta tctttttgta aaaaaggcga gtcaagtgaa atagccacaa cacactatta
    42481 cgaaatatta aaaaacctag aaaaataata gttatataga taaaacatat taaaaaatag
    42541 tggctttaaa ttttttaaag tcactattct atataaatat aacattataa aaaatatatt
    42601 aaactattta ctctttttta aaaccgttga ttttcttgct atataaaaaa ctattattat
    42661 agaaataact actagagaac ctctatttat aaagaaataa ttctttaatt cattaaatct
    42721 aacatctata ttattaggca tataaaacat cttttgaata taaaatccat ttacattaat
    42781 catactaaca aatgggtaca tatgtaaaat aaaaaatata tcagcaaatg tatatgtaat
    42841 taatattgct attgttgtaa atctattttt tgttaatgtt aatatcatta gtggaaatgt
    42901 tgtataccat aataatgtag gaaatgtctt taaaaacaca tctattggct ttacactata
    42961 aacaaaatct attttgtcta tgttaaaacc tttcactgac gtaaatgtat atactattgt
    43021 aattgaaatt aataataata cagtatatat agctaatata acacaccatc taaatactat
    43081 aaattgatta tatttttttt tattatataa agtaagtatc tcatttatat tacccaaata
    43141 atcttttgaa aacacataaa ttattgtgat tgctgacatt attggtataa aaacatctga
    43201 tatctttata attcctaacc atcctgctat agaatatgta tccattatag gtacatcatt
    43261 ataaaatatt aactcattat aatctaatat gcctgtaata aatatgcata atatagaaat
    43321 aattacaaat attaacacat gtttaagctc tattttttta agctcaaatt ttattaactc
    43381 caatatacac atttatttta actccttatg taaaaagttt atataagcat cttgtaaagt
    43441 tgtatctatc cttaagctat ccttaagttt ctctgtattt ttacctatat actttacttg
    43501 cacaccatct ttaactcttc tataatcaat aatatcaata ttacgttcta aatattcaaa
    43561 ttcatcatta gaaactacta ctgaatacac ctcaaccata tcaataaatt tattaattgt
    43621 accatcatat aatattttgc cttgatttaa tataattaat ttgtcacagt taaattgtat
    43681 gtcttctact atgtgagttg aaattaatac tatagaattt ttacttattt ctggtaacaa
    43741 tcttctaaat tcattccttt gctctggatc aagaccaact gtaggttcat ccataactat
    43801 taacttagaa tcacctatta aagcctgtgc tatacctagt cgtctcttta caccacctga
    43861 gtatgtacct attttattat ttataaactt gtccagatta acttttgata ctactttttg
    43921 tatatgtttc tttaaatcat tcttagatac acctctcatt ttagctacaa actctaagta
    43981 ttcttgccca tttatattat tatacatatc aaaatcttga ggtatatatc ctacatttgc
    44041 cttgattttc tcattgtttt tgctatactt tatattattt aattctatct ctccaattga
    44101 agtttcataa agagtcacta ataacctcat taatgttgat tttccagcac cattaggacc
    44161 taataatgca actactccat ctgttagggt taaatttata ttatccagag cttttttatt
    44221 tttgtaatta aaatttagat ttcttatttc taacttgttt atcatattaa cctcctttat
    44281 tatttatcta ttataaggat atttcctgaa agccaatgat aaatagttat gctaattttc
    44341 tctccctttg agtcttcata taaaaattca ttgctaggta agtcagcaac taatatcata
    44401 ttaatttttt ttctttttat tgattccata acattatcta cttcatctac atatttttta
    44461 gcatctacag atgctttgct atcacctaat atttcatttc ttgtttcaat taaaaattta
    44521 attttttcct ctatatccat atttacatta ctatctgatg gatagattat ttttatatca
    44581 tcttttacct cttctttaaa ctcacctgca tatattgcaa tatcatttga ctttccttca
    44641 aatatataat ctttttttaa aaaattacta gtcttattca gtaaaggtaa atttgaatag
    44701 acattatttt tagaacttaa atttatttta taagccatac aacttgattg atttactttt
    44761 gggtaccacg ctaaagaacc tggtggaagc ataatatcat ctttagtagc tatatattta
    44821 ttttgattcc aagatgtcaa cacattaata tagccttcat actctatatc taatgtcacc
    44881 tcgtcattag gctctaaact ttcctttaaa ttaacttcaa ttaaatcctt ttttttgtta
    44941 aattttatat tttccgaatt tacttttata tattttatat caaatatttc atctaaaatc
    45001 atattaatat ttgttaactc ttcatttgat gtgtttaata aaacaattct atcttttata
    45061 tttgacttgc ttttaaagtc aatcttcata tcatgcgatt ttattttaat atcactaata
    45121 ttagatttct ttaaatactc tccataacta cgttcctcat ctctatatgt tgacatatct
    45181 attgatatat aatttaatcc aataaataaa atactgtaca ctactataac tattaatgat
    45241 ttaatctgtt tctttctaat atcatttaat atcagatatg ctactattat taaagtaatt
    45301 gcaaatagtg taggtataat cttatctata acatatgctg aattattaac tttccctaca
    45361 aaatcagaat agtaagcata tgattgatct tcaaatatat taagtgattt aaataatgct
    45421 ttaaaaaatg gttctttaat atcaataact ctatccaaca tcttagttga tgttaaatat
    45481 aaaaatactg atgataaggt aatctttagt attaaattat ttataataac tgaaataaat
    45541 gatatcacta tagataaaat agtaagtggt aaaaaccatt caaataccaa tataaatata
    45601 gttgatttaa tcgttacaat tgataatgtt cttattaaac ttgagtatgc tatagcatat
    45661 ataattggta tgcaacaaaa tataaagttg tttctagtta cagcaacaga aatacctaaa
    45721 aaataatcaa aattatttct acataatatt tttacagtat cataactttt tctcatataa
    45781 aaaattacat ttaacatggt taaaatacta attgtcatac aagtatatac actcaaggat
    45841 aagtaatcat taaatgaaat tcctctattg gatatatgtg tccatcgttg tatgagatgg
    45901 taatttataa taataactgt tattgcaaat aaaatatttt ttctaattat tttggttata
    45961 aagtctgata taaccttaat actactcata tttatgcccc tcctagccaa tcctttgata
    46021 caacttacaa tagattcaac tatatttaat aagttcaaat acttaccttg acattatttt
    46081 tttaaagtta atattaatta gtgaagttaa ttaatttaga aaatgtttta taatcttact
    46141 gatcactatt aaccttcatt ccaacatata ttaatatagc aatccaatat atagaaatta
    46201 ttgcataaat cacatattgc tgaaaaatat taagtatttt acataaaata attaaacata
    46261 ttattacgaa tagtattttt tgcacagtct ttctataatg ctttttctca ctttcactaa
    46321 gaggtttgtt tctatgttct aaaggagcta acttgtaaat tgttagtata ctaataatca
    46381 ttaataatac taataaatac ttatatttat ttatatctat attattagct gaaaaaatag
    46441 ttatcaaata aataactgca aatgttaatg tacactcttt ataattccta gcatgataac
    46501 ctcctgtgaa ctgtcttaaa gtgcaataac aacttaaaaa tataactgta tgtataaatc
    46561 tatcaaaaat aattcctata aataatgcta ccgaaatatt aactatgaaa taaatcaaag
    46621 tttcaaatcc atatctatat atttcaaaat cttcactttc tacaatctca ttattaacta
    46681 atatattggc aaatttatat gataatcttt taaacatatt tcctcctcaa catgtaaaac
    46741 ctctccttta ataagaagag gtccttttat taatgttatt tttttagttt ttgtaaagct
    46801 tgtggctctt ttgcctgatg tgctacccaa gaacttgcac tgtttgctga taatacagct
    46861 atcccaaaac ttaatgctga gatgttttta agtaagttta acgctatttt tttcattttg
    46921 tactctccta actttttatt ggtatcatta tttttaatat aaactcatta tctgagtaat
    46981 taactattgt ttcaccacca tatttattta ctatatattt aatactagca agtcctattc
    47041 catgtatctt atcatcatcc ttactagttt gaatacgttt atcaataagt ttaatatcat
    47101 ttaccttagt atttataaat tttattattg caaatttatt tatatatgta gctttaactt
    47161 ctattctttt ttctagctca ttatttatat ccatacatgc ttcaattgca ttatctagtg
    47221 aatttgcaaa tattgaacat atatcattat tttcaataaa gtttaattta gatatattta
    47281 tgttatcttc aatttgaata tcatactttt tacaaatact tattttttct gctaaaatta
    47341 aatctaatgt tttatttcca gtatttttaa aatgttcaaa ttcacttatc tgaaactcta
    47401 agttatctat atatgatata atttcttctt tagtgtcata attttttata caaatcatat
    47461 ggtttttcaa atcatgataa acatatttta atctatcatg aacttcgttt atattttcat
    47521 aattcctgta gtttgttttt attctttcat ttataagttc atactctaga tttaatttat
    47581 cgtcttgtac aattttccct attactatta aaagtattat acttgatgat aaaatcaata
    47641 aaattacaaa tataaatata aataagtttt ctgtagtaat tgtattgact cttaaattat
    47701 attcaaatat aagtaataag ctaactatat tagataatat aggtattcct attagtatca
    47761 tatctttagg tttaaaatct aaagataatt taaaatactt aaacaatata aaacctataa
    47821 ataaaaatac ctttgacata ataatagctt gtattctaaa taagttttca tgttgtgtta
    47881 tgttaatatt atttaattta tttataaata ctactagacc tactgcagaa ccttcagcaa
    47941 tcattaatcc tagccaaaac aataaactaa ctattatact tttatatatt ttatcttcat
    48001 atgatgttat ataaaatgat attcctatta ccatacatag aagaatctta atatttggaa
    48061 acactttaac tacatttatg tatgccataa atataaatat aattattgtt gtaaatatat
    48121 atcttatatt agatattttc ctctttccaa ctaagtggat tactaaaaaa aatataatcc
    48181 aatctatagt acctgaaact aaattaataa tattccaaaa tcctatactt agatttgtta
    48241 gcatactata tcccctaata tattagttat agcaagtttc aagcctttaa ctctatattt
    48301 acttattgga atacttttgc catctactat aacagtactt ccactcattg attctactaa
    48361 ttttaaatta actatatagc tattatgaca tctaaaaaat ccatattcat ttaatatctt
    48421 ttctatttta gatatactca ttttagtaat atacatatca tcatgtgtat aaatcaatat
    48481 attcggtcta tctgtttcta tataagtaat agaatctatt ttaattcggt ctacataatt
    48541 ttttacattt atagttaagt aattatttct ctttttcatc atctcattta tacaaggtaa
    48601 tacactttta gaaatttttt ctttatttat tggctttagt atatatctgt atgcttttac
    48661 ctcataacct tcttgcataa actctacaaa tgaagtaaca aatattattt ctaacttatg
    48721 atcaaactct cttatcttcc tagcagtatc cataccattt attgttttca tttgtatgtc
    48781 cataattaat atgtctaaat ctttaggata gttatttagt aactcttctc ctgatgaaaa
    48841 ttcatatatg ttataattta taggatatga acttaatatt tcacttaata tatcttttat
    48901 ttttattcga taatgtagtt catcatcaca tattcctata ctaatcacaa ttcttaaaca
    48961 tcctttctta tatattttta ataaatatat aaaatttcta ttcattttac atattttaac
    49021 atacttctgt agcaaatagc tatttagatt ttaattttag ctttttggac attaagtatt
    49081 actttttgga tttacaatct attttaattt tcattataat acaatttttt aatatatatt
    49141 gaatatattt agcgatttta ataacatatt cttcgagaag tttttagtat ctagtttttg
    49201 ttaaacaaaa agtatgcacc ttccttttta tagtaatatt ttaattatcg ctataatttt
    49261 gaagaataca cactatattt taaatattca tataaaacat attaaaaaat agtggcttta
    49321 aattttttaa agccactatt tttttaaatg atgttcctga aaatatatta agttagttat
    49381 tctaatcaat ttgaagactt ttgcttctcc ttgcctatat ctaacataat ttcataattt
    49441 aatttacctt tctttaaatc aactcctgag ttacttctaa taatcccaca atccaacatt
    49501 tcgtcaaata ccttcctaga taaacctagt ttctcacgta ataatgttga tacctttaac
    49561 tgacatggat atttactaat aatatgaact tgtgtaaggt cattaatatt aatttcttgt
    49621 cctactattt tatactctgg aataccaact tctgctccat ttctatgtaa aagttccgta
    49681 ttcatagcat attgcttaac aagattataa tcgtttgtat ggaattgttc tagtatttct
    49741 ggatttaagc tttttggatt aacacgagaa tatatagttg agttccatgt tgaatcacaa
    49801 tttgaacact tgtatattaa ccatatatcc aaatatttat gttgagcatt aaccctaaat
    49861 aaacctgaac aaatatattc agtctttttt ccacatttct tacaatacct aattacaggt
    49921 aactgggaga tatattccac ctcccaagta atttttttca taaatgcaac ttcctttcta
    49981 taagattact aaattaatag aaagttatga aaaggtggaa tataatcaag tatttttttc
    50041 aaaacaagac ctcctaattt taataaattt taatttcaaa catataaaaa gctactactt
    50101 cttattagat actttacaac tctattcgtt atctgctgta caagttattg aaattattta
    50161 aattatagca tccacttata agaaactata cctcaaacac ttttatcaaa agaaaatgag
    50221 ccagtataat tataaaacta tactggctca ttcttaacta tcttttcttt tttcttgtaa
    50281 tacaattctt tgaatacttt tcaaagacaa gtaatatttt tctgataaat atttcaaatc
    50341 atatccaatt tgataatctt cataaatttg catatttcta attgataaat cttcacgagt
    50401 agacgtacta cttccccatt cttttttatt attagacttt ctaggaatat agatatattc
    50461 tccatctaca tattcctgta tcaattcaag taattcttct ggtaatatat gtattgcttt
    50521 tttatagctc attctgcact cctattaaat aataattttt tattaggaat agcaaagggc
    50581 tatttatata ttaaatttta tatttgcaat agcccttgct atgcaaaaat aaagattaaa
    50641 tcaaacataa atctcacccc tccttatata ttgcaacgat acatataagt ctatcagcag
    50701 tataaatagt tgtcaattaa cataacttct tcatctaacc tttatattat ctttatttat
    50761 tttcataatt catctatttt agagactaac ttttttcttc ttattagata tatttaaagt
    50821 tattaatcaa cataagtcct ttatcttgag ggatttatta ccgaacaagg aaccccaact
    50881 atacactttc cacaaatatc acaaccacct atataagtgt attttttttc atttatcata
    50941 cacatttcat aacacttatt cctattaaat ccatcttctt ttaaagcttc tttcacgcat
    51001 ttgttgatac attttttgca actattatta tgtttataca agcagtattc attttctggt
    51061 cttttagttg gctctaattc taaacttgtg attatgcttc ctattcttcc acaacaccct
    51121 ttttctgtaa taagcatatt atttaaacca aatgttccaa gacctgctat gaatgctaca
    51181 tgtctttgtg accagtcact taccaatttt tcactgtcaa aattatacga cccaggaata
    51241 gcatatgaat tagcccccat cttctctagt tcttcacata agaaatcatt taaatttgaa
    51301 atcaacatat tagtttctat gtacgctctt gcccatattt cagaacattc aaaccctcca
    51361 atattactat tatttacact ttcatcaaaa ggtataaaat atgtaattat agtttttcca
    51421 ttttccagaa aatcttttgg catagcatga gatgttccta caacactttt tagcttctga
    51481 aacatatcat cttcagcaga tgcataagca aacaaaagtt cttgccactt tgtagttata
    51541 ttatttgatt tatgataatt ttttacaaag ttgttcattg atgtttcaat cttatttttc
    51601 atagtatcac ccctagataa ttctatattt ccaatttaat gttattattt tatattatat
    51661 aatagtattt tataatatgc gcactaatta atattaaaac tatgttcatc aatcattctt
    51721 aaaaaagctc ctaatatcaa tacgatatta gaagcctttt cttatctaat ctaatttatt
    51781 gcaattcctg cacttgcata tcctgctaca gtattaacta atgaaagacc tgaagctgtt
    51841 gcagtaaata ctagtaagaa tcgagtttct gctgttgctg ctatatttaa tcctgttaca
    51901 attccactag aaattgaacc aactgataat atacctgtaa gtggtggagc tagtgtaact
    51961 gtcgctcctg gtacagctgt aaatgagtta tttggtgcag tagattggta aagtgttgct
    52021 gtaattgtaa ttgttgaacc aacaagtgaa agtgctgctg ttgtactgaa gtatgctgaa
    52081 atagatgtta ttgttccatc tcttggcatt gaaaatgcaa agttagtcaa tgtccctgct
    52141 gcgtttgtaa ggtctattac tccaccaact atacttaatc ctggagctga actaccaaag
    52201 ccaacaaaac ctggtgtacc tactaatcct ccagctatag ttgtaagtga tagtggtata
    52261 cctgatgcaa aaggtattat tgcactagca cctgttgggc ctgttggacc tgttgcccct
    52321 gttgctcccg ttgctccggt tggacctact aatccatctg cccctgttgg acctgttgct
    52381 ccggttgccc ctgttgctcc atctgctcct gttggacctg ttgctcctat tgggcctgtt
    52441 gctccggttg ctcctgctaa tcctgttgct ccggttgctc ctgttggacc tactaatccg
    52501 tctgctcctg ttggacctgt tgcccctgtt ggacctgttg ctccatctgc tcctgtattt
    52561 cctgttgctc ctgttgctcc ggttggacct gctactccat ctgctcctgt tgctcccgtc
    52621 gctcctgttg gacctactaa tccatctgct cctgttggac ctgtcgctcc tgttgctccg
    52681 gttgctccag ttattcctac tccggttgcc cctgttggac ctgttgggcc tactaatcca
    52741 tctgctcctg ttgcccctgt tgctcctgtt ggacctacta atccatctgc tcctgttgga
    52801 cctgttgctc cggttgcccc tgtcgctcct gttgctccat ctgctccggt tactcctgtt
    52861 gccccggttg gtcctattag tcctgctgct cctgttgccc ctgttactcc tgttgggcct
    52921 gttgctccgg ttgctccggt tgctccggtt ggacctatta accctgttgc tcctgttatt
    52981 cctattcctg ttgctcctgt tgcccctgtt gggcctgtta ttcctattcc tgttgctcct
    53041 gttgctcctg ttgggcctgt tactccatct gctcctgttg cccctgttgg gcctgttggg
    53101 cctgttactc ctgttgctcc atctgcccct gttgctcctg ttgctccatc tgcccctgtt
    53161 gctcctgttg ctcctgttgg acctgttatt cctattcctg ttgctcctat tgcccctgtt
    53221 ggacctgttg ctccaggtgt tcctgtcgct cctgttggac ctattaatcc tgttgctcct
    53281 gttactccta ctcctgttgc tcctgttggg cctgttggac ctgttactcc aaatcctgtt
    53341 gcccctgttg ctcctgttgg acctgttatt ccatctgctc ctgttgctcc cgttggacct
    53401 gttggacctg ttactccatc tgctcctgtt gctcctgtcg ctcctgttgg gcctgttgga
    53461 cctgttactc caaaccctat agctcctgtc gctcctgttg ggcctgttcc ccctgttgct
    53521 cctgttggac ctcttaatcc tgttgctcct gtattccctg tatttcctgt tgggccagtc
    53581 ggaccggttg gtcctgttgg gcctgttgcc cctactcctg gacctgttgg acccgttggt
    53641 cctgttgggc cggttctacc tcttggaccc attgggcctg ttggacctac acatgatggt
    53701 ggacagcaat gatggcaatc acagctatta taatcatcac gaccattgtt acaatcatca
    53761 tatttatcat agccattgtt gtaatcatta tcatcaaatg gtccaaaata tttatttcta
    53821 ctcattatta aaagcacctc ctgatatatt tgagctttta agctctatat ataatatgtc
    53881 aaatttagta tgattgtgac ctatcaacta tttttaaatt tactaaaata attttcattg
    53941 tgcaaaacag cactatcgtt aggtttgatt tcttttgttt tttcatgata ataaatagct
    54001 ttatctgatt ctcctaacct gtcataacag acacttaatt gtatagatgg tatatatcca
    54061 taacaatcat ttgacttaaa acctccatta gtatcattct tatctcttgt taatgctacc
    54121 ttataccaaa aaatggcttc tttatatttt tgtctatcaa acatatgctt tcctatgtca
    54181 caacaaattt ctgctcttgg ctcatcaaat tcgaaacttc taaacaatga atataaggca
    54241 cttttttcat cattaattaa gtaataacat gtggctaaat ctctgcaagc actgatacaa
    54301 tcctcaatcc atcctcttga tgagtctaaa aacttagtaa aaccttctat tgcttcttta
    54361 tacctagcat tatagtacaa ctctctagag taatagaatt ggtgtcttgg ctccaatgtc
    54421 tttccttctg aaatcatttt ttcaaaaatt ctaagatttc ttagagggtc ctgtctatga
    54481 agctttttat gagatattgc aatgtcagaa taaaatacct ctccaaaaag aggtactact
    54541 tcatgaatag ggtcaaccca tttatgatta gaacttcttt taaacaatcg ttctctataa
    54601 tatgagagag ttgggttacc attttcatca aaggatacat tgtattttgc cataacaata
    54661 tcaatggaag tatccaagct ttctttaatc tttaataatt tttctctatc agcttctaaa
    54721 attatgtcat ctgcatcaag ccacatagta tagtctttag aagctttaga aaatgaaaaa
    54781 tttcttgcag cagagaaatc atctatccat tcgaaatcgt acaccatgtc tgtatatttt
    54841 gagactattt cttttgtgga atctgtagag ccggtatcta caattataat ttcgtctact
    54901 atatccttta cacattctaa gcatctgcct ataacttctt cctcattctt aacaatcatg
    54961 cacaaactta ttgtaatcat aatgtacaac tcctttgtct tctatatatt gcagacataa
    55021 gtaatatatg gtattttctc ttgttttgtt attaaattta taaaaacttt tgacgacaga
    55081 aagttactaa agaaccttat cttttatgta ttttttatag tagaatttat taaacttgaa
    55141 atttggtaat aattgttgaa atgataaaac catatttaat ttcatacaaa aaagagtgtc
    55201 ccataaacta aaaagttcat tttgagacac tcttatttaa tattatatat atatttgtaa
    55261 aacagacatt ttaatatgat actttgatac tttattcatt cctattcatt atataatcaa
    55321 tcagcccgta ctctttagcc tctagtgcag tcataaaatt atctctatct gtatctcttc
    55381 taatatcttc tattgattta cctgtatttt cagaaagaat tttatctaat cgttctttta
    55441 ttttcaatat attatctaca gctattttta catctgttgc ttgaccttta gctcctccca
    55501 ttggctgatg aatcataatc tctgaattgg gtaaagcaca tctttttcca tgtgttcctc
    55561 ctgcaagtaa aaaagcactc atacttgcag ccataccaat acaaatagtc gatacatcac
    55621 atctgacata attcatagta tcatatatag caaatcctga tgtagcagag ccaccagggc
    55681 tatttatata tataattata tctgaatctg ggtcttctga ttctaaaaac agtaattgag
    55741 ctactactaa acttgcaata gcatcattaa tttcttctcc tataaatata attctatctt
    55801 ttaataattt tgaatatata tcataagacc tttccccttg acctgtttgt tcaattacat
    55861 gtggcactaa actcatgcta ctttcacctc acaattaata ttaaagttaa gataagaatt
    55921 gatttcatct cttctttgtt tataattcat atttgcataa gaaatacatt tttcgctttg
    55981 aatttgatga tttagattta aaacaaatct ctgttgaata ggataaaatt catctttatt
    56041 tctatatact tgtggagatt ctttatataa atttctaaat gctagtgtaa aagattgatg
    56101 tgtagaatat cctactttaa tagctatatc tataatatat ttgtctgtaa atataagttg
    56161 tctagctgct tcagtaagtc tcctcctctg tatgtattga tggatagtac atcctacaac
    56221 atttgtaaac attctgtgta aatggtattt tgaataatta gcaatataag ctattttatc
    56281 taaatttaga ttttctgtaa gattttcttc tatataatca attatctcca taataacatc
    56341 tgtatttgtt ttcaactcta tcctctcctt ttaagtatta taacctatgc aaaaagtttt
    56401 ttcttaatat aaattgctat cttaatttag tgtatagcaa taaagtatcg ataaaacaat
    56461 atcaggtatt tttatacaaa aatattaata tatatttctt ttaaagttta aacttaatta
    56521 catctattat atgtagattg ctacatgttt tatctatgta ccttgattca tatgtattat
    56581 tttgctgagt atttttacac ctttttcaat ttcatcaaaa ctaagatgag cataacctag
    56641 tataatttca tggtcatatt ctaatatatt ctcaattgca tattgttgta taggataaac
    56701 ttttatacct gcttcaaaaa ttttatgaat taaactttcc gtaaatttaa cattatagaa
    56761 atgagcaact atatgaagcc ctgctgcttc accttttatt ttaaattcat ttttaaattc
    56821 cgtgtttaaa acttttatga gatatttatg ttttctattg tacaacttct tcattctaaa
    56881 tatgtacttc tctaaacctc catttccaat aaattcagct aatacatatt gcaatattgt
    56941 ttctgtatga acatcagagt acatttttaa ggttttatag ctttctaaaa tattgtctgg
    57001 taataacata aatccaacac gaatagctgg agataatatt ttactaaaag aacctatgta
    57061 aattacttta tttgggctaa gttcataaag agaactaatt ggttgaccct catatctaaa
    57121 ttcactatca taatcatctt caattatata gtaatcattc tctgttgcac atttaataag
    57181 ctctagtctt ctttgaatag gtaaaatccc tcctaatggg tattgatgag aaggtgtagt
    57241 ataaacaaaa gaaatcccct ttattgattt tattaagttg gtattcattc ccttatcatc
    57301 tactttaatt ccaacaactg aatatccaat agatgaaata acctttaata agcctttatg
    57361 aatagggtct tctacagcaa cctttttatt acttttgtat aaaagctgtg aaattaaaga
    57421 taaaccttgt gttgaaccag aaacaatcat aatgtttttg ggattacatc taattcctct
    57481 agtacgaaat aaatacttag atatttccac tcttaaaacc catacaccag ctgtacttcc
    57541 atatctgaaa tccgaatctg ataaatcata cagtatttgt ttatatagct ttgaaagttc
    57601 tttgcgtgga aatagtttta attctggaac tcctgaacga aaatctatat aatttttttg
    57661 tttattagta tgtaaatctt tttcatctct aaaagtatca tttaacttaa aatcaacttt
    57721 atgccctgat attcctttag ctacaattgt tccatatcca ttccttgttt ccaaatatcc
    57781 ttctgcaatt aattgattat atgcatctaa aactgtatta cgagatacag atagttcttt
    57841 tgataaagtc ctagatgatg gcagtttttg ctcaaacttt aagcttccat ccagaatcat
    57901 atcttttatc tcacaataaa tttgtcttga taatgatata ttactatttc tattaatcgt
    57961 aatccacatt ctaatacctc caaaagtggt tctataaaat tactataaaa atggaactac
    58021 aaaatccact tttaatttgc taagattata tcataaaata taaaataaaa aggagtctat
    58081 attatgttag aaatatcaca taaagttaaa gaaatttatc ccaatattaa atttggagtt
    58141 atggttataa atattacaca ttcaaaacct aataaagaaa attttttagt tcttaaaaac
    58201 tctacaatta aaaatattat agaacaacac ccagaataca atcgtaaaga aaaaattaaa
    58261 acagagcctg tttcaagtta tataaagtat tataaaaaat tcaagaaaac ttaccctgta
    58321 ttgcttcaat tagaatctat tctattaaaa tcaaaaggta tcccagatgt aggtgtaaca
    58381 attgagtcaa tgtttttagc agaattgaaa aatcttcttc taacagcagg tcatgacctt
    58441 gataaaatgg aattaccttt gaaaatagaa ttagcaaatg gaagtgaaca tttttatggt
    58501 ataggtggta aagagcatat tttaacaaaa gatgatttat ttttatcaga taatattggt
    58561 atattatcta gtattcttaa tggccctgat aatcgaacag ctataacaaa agatactaaa
    58621 aatattatgt attttgtata tggacctgat aaaatatcag aaaagcaaat tcaagaccat
    58681 ttaaatgaca taaaacacta tatttcaagt gcttttccag atttaaaagt taattcaatt
    58741 gatatatttt agttaatata ttaaaatcct cataaatatt ttgaataaat aaattagtga
    58801 agtatacatt ctagttaaac tagatatact tcactaaaat taattatatg tagatattat
    58861 ttattttgaa ttttgtttat aataaacact ttattacatt tatcctatga ataacttaat
    58921 tttataatta aagagtttca taagaaacaa tttcacttaa aggaacacga gttttttcat
    58981 gtctctctgg gctctctggt atcttagatt catatcccat caataatata tttattggtt
    59041 ctagattatc tggcaaacta aactcttctc taattatatc tggattaaaa tagcacaccc
    59101 aaacacttgc caatccaagt tcagttgcct gtaacatcat atggtctgta actatacttg
    59161 tgtcaatatc tgtaagttgt ttcccatcaa aaggtcttgt ccaaactttg tctttatctc
    59221 cacatacaag aattgctaat ggagcatcat atatattggc agccttagaa agtttattta
    59281 taccttcttt ttcctgaata acaatcaatc tttgaggttg acgattacca ccagttggag
    59341 ctattcttgc aacatctaaa accttctcaa gtttttcttt ttcaaccttt ctatcttgat
    59401 aattacggca agaatatctt ttttttgtaa gttcaacgaa attcatttat ttacccccta
    59461 ttgttttatt aggctaagtt gatgatttat ttaacctatg ctataatttt atcactatgg
    59521 tactatatta caataatgca cttttttgta atatagtatc taaaaagata ctttaaaata
    59581 aataaaggag ctcaaaaatg aaaaaatgtt tagataatta cagttgccca atagaagcaa
    59641 cacttgcatt gattggtggt aaatataaga cacttatact ttggcatctt aaagacacta
    59701 tattgaggtt caatgaatta aaaaaattaa ttcctaaagc aacgcctaag atgttaactc
    59761 aacaattacg tgaattagaa tcagatggtt taattataag agtggtttat cctgttgttc
    59821 ctccaaaagt agaatactcg ctatctgatt ttggaaagag tattattcca attttagatt
    59881 ccatgtgtga ctggggttct gattacttag aaagtctata gagcattaca gtttaaatcc
    59941 cattgctaat ttaacttcat ccatttgttc tttagatgtc aacatttcta aaagcttaaa
    60001 agctacatgt ggagctgttt ctggacaata tgaggttata atatttttat ctacaacaat
    60061 tggttcatta actacattta catcaaactc acttaactgt ctttgtcttt taccattttt
    60121 caaatgatat gtagtagctt tacgattttt taaaacacca ctttttccaa ctggcaatgc
    60181 tgccacacaa atagaagcga ttattttttc ttttgaatta aactccctta ttagatttaa
    60241 aaaagatgaa tcatatgctt catcataaaa tccaaattct tcaaatcctc caggaatagc
    60301 tagagcatca taatcatcaa cacatacttc ttctatcgtc ttatcaacta atacttgtat
    60361 attaaatgtg ctcataactt gttttttaaa tccacaagtc actacatcaa tatcatgccc
    60421 ataatcgtta cgagcccatc ccataacatc tacaaataca ctaaattcca tagtttcaaa
    60481 accttttgct aaaaaaacta aaactttcat attctatttt cctcctaaaa tataattaac
    60541 actttaatag taaattattt aaaaaatatc ttttattgta ttaaattctt ctttaattgt
    60601 agataaaaca atggttgtat tagctttttg aatcccccca atttccttca aagtcactga
    60661 tataaactct tcaagattac ttgtatcttc tgctaatact tttattaagt aatcatactc
    60721 tcctgaaata tgatgacatt ctaatacagt atcatattcc aatatagttt tcttaaattc
    60781 tttcatactt ttagataaat cagtattgat aaatataaaa gccaaaagct tatattttgt
    60841 tttttcccga ttaatttgaa tagtgtactt ttgaattaaa tttgactgct caattttcct
    60901 tatacgctct gagactgctg gtactgataa attaatttgt ctgcttattt cagaggttga
    60961 agccctacta ttctttttta gagaattaat tatttttaaa tctatttcat ccagagctac
    61021 tcacctcctt aattatttaa tacaatttta gctaataatt tacattaagt aaataaattt
    61081 aatcatttca ataaaattta atacaaatat gttatttttc cttaaaattt tagttttctt
    61141 taatcaaaac acatataata cttaaaatta tttaagttga attaatgttt ttattttgta
    61201 taatatatta gaaccttaat atatcattga aaattcaaca atactagaca tatacttcta
    61261 catgttgtaa tatttatgaa aatagtatcc ctatatcaaa agtataaaac tcataatctt
    61321 aattttccca tagactataa aattttattg gtagcgagtc ttcaaataac tttgtaatga
    61381 tagatttact aaattaatat aatatatagc aaatataact ttcttattga ctataaccaa
    61441 gtattatgat aacataactt aagctataat taataaaaca tattttaaat aaataagata
    61501 atccacaaag tacaaaagta caatttaaat atagataaac tagaattaat actaagatta
    61561 ggatgtgaat aattatgatt tatatagaat tagttaaact tgttagaaaa cttaactcta
    61621 cacaaatgta tacgatgaag cgttgtgtag aggttaatct gaaagcttaa agctttctat
    61681 cttcatcggc aaatataggt ttagtatagt tttttggcta tgcttattta aaattaccta
    61741 tttgccgata gataatatag attttctggt catagacaac aatgcttgtc tatgaccttt
    61801 tgtttttcca aaagcagagg tcggcatttt acaatgccat tcctctgctt tttttatttc
    61861 cataaatttt ttaataaaag aaaaggagtt tgaattatga gtttattaaa agtaactaat
    61921 ttatcacaat gttttatgga taaatcactg tatgagaaag ctaactttga tttattcaaa
    61981 ggtgagcata taggtgtagt tggccaaaat ggtgcaggta aaagtacatt aattaaaatt
    62041 ttattgggag aagttgttcc agattcagga gaaatcaagt ggcaacctaa tatcaatata
    62101 ggccatttag atcaatatgc agaaatcaat agagatacaa caatatcact ctatttacac
    62161 actgcatttg aagaacttta taaaatggaa aaggaaatga atttactcta tcaaaaaagt
    62221 gctatatctg aaaatgagca atatctaatc aaagcatcag attatcagga acaactaata
    62281 gcaaataatt tctattctat agataatgaa ataaataaaa tagcaaatgg tcttggatta
    62341 gattcaatag gaatgaattg tgttgttgaa gagcttagtg gtgggcaaag ggcaaaggta
    62401 attttagcaa aattgctact ttctaaccat gatgttctat tattagatga accaacaaac
    62461 tttttagata aagaacatgt tgaatggctc tcaaattatt taaatacatt taatggggca
    62521 tttattgtag tttcccacga ttttgatttt ttagaaaaaa tttctacagg tattcttgat
    62581 atagaatttg gtatgattaa aaaatatcat ggaaaatatt cagagttcct taaacaaaaa
    62641 tcacatttaa gagaagatta tattagaagg tatcaagcac aacaaaagaa aatagaaaaa
    62701 gaagagacat ttatacgtaa aaataaagct ggagtaaatt caaaaattgc aagaggaaga
    62761 caaaaacaat tggataaaat agaaagaata gctcctccta gttttacagg aaaaccaaat
    62821 attcaatttt cagaaattga aatatcggct caaaatgctc ttactataac aaatcttgaa
    62881 gttggatact actattcttt acttccaaaa ttaaattttt ctgttgatgg aggtcaaaaa
    62941 atagttataa ctggttttaa tggaatcggt aaatctacct tgttaaagac attagtcaaa
    63001 gatattcctc gtatatctgg agatttccag ttttcagaac aagttaaaat tggttattat
    63061 gagcaagatt taaaatggga aaatcctgat aaaaccccac ttcaaatagt agcagataaa
    63121 tatccaaaat taaatacaaa agagattaga cgtcatctag ccagatgtgg tgtgaaggaa
    63181 gagcatgttt caaggagtgt atctacttta agtggtggtg aacaatctaa ggttaaatta
    63241 tgttgtatga tgttatctcc ttgtaatttt cttattctgg atgaaccaac caatcacttt
    63301 gatgcagaga caaaggatgc tttacaaaat gctttgaaac agtttagagg aagtataatc
    63361 ctagtttccc atgaagaaaa attttataaa ggttggattg ataaagtgtt taatatagaa
    63421 aaacaattag tataagttta tacacaatat acaatattat ttaattgata tttcaatgca
    63481 aattttaatg ttctagttaa tgtttcactg caaataaact aaaaaaattt tattagaaca
    63541 taaagtacat taccaggata taaacttaat gaggctatct caaaatagag atagacctct
    63601 tcttcattgt tgagataacg aaaatacatt tgattttacc cataaaagaa ttcctcatta
    63661 actaaaaatt caacttgaga tatcttcatt aatattaaaa tctattctaa tcgattctat
    63721 tcacaagttt atatcctagt cctttaactg ttataagtat tttaggattt gaggggttat
    63781 cttcaatttt ttctcttata tgtcgtatat gcaccataat tgtattgtca caaatactac
    63841 tatatactcc ccatacttgt tcatagagtc tttcttttcc tataatttta tttacatttt
    63901 gagccatgta gcttaaaaga tgatactccc ttccagttaa ctcaatctca tttctatctt
    63961 tatatacacg gtttccttct atatcaatag taatatctcc tattttaata actgcactat
    64021 ctgatggtac aatgctttga tactgttgtc tacgtaattg cgctttaact cgaaaagcaa
    64081 tttctcttgg actgaatggc tttgttatat agtcatctcc cccactacta agacctagta
    64141 ttttgtcaat atcatcattt tttgatgata aaaaaagaat agaacagtat gaaaactctc
    64201 gaattttttt acacacttct ataccatcta tatctggtaa cactatatca agaatgacaa
    64261 catctggaca tgctatctta cacagcgaaa tagcatctaa accattataa gctttaataa
    64321 tgtttttaaa accatcattt atgagtactt cttcaattaa atctactata tctttttcat
    64381 catcaacaag taatattttt ttattaaaat atgtatccat attgaaatct ctccataaaa
    64441 gtttattata ttctaatctt gcagtatcaa tatcttgttt ttttatattc actactcttg
    64501 cttttacatt actaatagta acatctctaa tagacaaatt caatcactat gaaaattaag
    64561 ataagtttct ttaaaataaa gtgtatgata cattaaaacc tatagaaaat taatttcatc
    64621 caaagtttat aatattagac taatacactt acagatacag atacagatta atacaatagt
    64681 aaaataaaag gagttgtctt aaaattgact ttttctaatc aaactttaag ttcaactccc
    64741 ttttaaactt ttatatgtta tttttattaa ttctttatat caattataac tttaattttc
    64801 aatagtatat atctaccact aattgaatta cttattaaaa cataaaatat ctacctaaac
    64861 tatttattta atatctacat atatttatat ctattcttat acttacatat acaaaaaatg
    64921 gttaaaaata aagttaaaat ctcagcactt ggtactgcta accatatccc atttatattt
    64981 aatatatttg gcagtatcaa taaacctata gttataaatc caaatgtacg tagaaaagat
    65041 aatattgcag agaccttgcc atttgacaat gctgtaaaca tagatgaggt aaaaatatta
    65101 tatccacaaa aaataaaact aaaagaaaac atataaaatc cagaccttgc aatttcataa
    65161 acccggcttc ctctttgaga aaaaatctct acaatgattg gtgaacatga tatagaaaag
    65221 ataaatacca ataaagatgc cactgaaata aataatatac aaatcttaaa aacatgattt
    65281 aactgtgtat tattttcact tccatagtta taacttatta ttggtgcaac acccattgag
    65341 aaacctatat aaagcgaagt taaaagaaat tgagaataaa taattattgt aatagctgca
    65401 accccatctt caccaattaa tttcatcatc atagcattaa ataaaaaagt agtaactgct
    65461 gttgatagtt gacccaccat ttcagatgaa ccattaaaac aagcttcaaa taatattctt
    65521 ttatctagtc taggtataca aaacttaagt aaccctttat tttttgaaaa gaaaaccata
    65581 cctgaaacgg taggaattag gtatcctact ccagttgcaa gtgctgctcc actaataccc
    65641 atttgtaaca gaacaatgaa cacatagtca agaattatat tagcacaccc agcacctaac
    65701 actagccata atccaaattg aggctttcca gctgttacaa ataaacattg aaataatact
    65761 tgtagtatat ttgcagaagc aaaaaccaag ataataaaaa gatatgaacg acaatattta
    65821 attaaaactt cacttgctcc taaccatata atgatataat ccataaatac aatacctata
    65881 ccagtaatta ttaccccaat tacaactcct gataatacga ttaaagaaaa agctttattt
    65941 gctccctcaa tatcaccatt tcccatctta cgtgctacaa tagcacttcc tccagtggca
    66001 agcatagttc caattccaac tataagatta ataattggac atacaatatt aattgctgat
    66061 atagcatttg tattaataaa tcttgataca aatatagtat ctacgattgt atacaacccc
    66121 ataaaaatca tcataaaaat agtaggaaat gcaaacttca atagagtaaa taaattaaat
    66181 ctttgtgcca gtaaattatc ttgctcataa agattatctt gttcatgatt ttctgaataa
    66241 tatacatcac tcattttgtt tatttttctg tacattaatt atttttaaaa tatattccaa
    66301 acaattagac atttacagac ctcctttctg cataagaatt atatctaatt atttggatat
    66361 agttttaatt aatcttgctt ttttacacaa ttatatttct actaaagaaa cttttaaatc
    66421 cttactttaa tcattttata gctttcagtg cctttagcgc aaatacttgt tcacatagtt
    66481 tagtgtcata tgaaacgtat ttatatatag ttatacattg tctattttta ctaatttatt
    66541 aactacttgc acttttataa tgtctcatac ctaacttcca aaatctccac ataaacaatg
    66601 taaacaaaaa tacaattaaa attgagtata ttaatccatt aattgttatt gtcccagcca
    66661 aaatttgagt cggaattgtc gacataattc catatggtaa gattaaatag aataatactt
    66721 taaaaacacc ttcatatatt acaccaggaa ttttcatatt cattggcaat aaattatctt
    66781 ctaatctcat tatcgcagaa gatgatataa caaaaaatga aactgttcta agtatgatac
    66841 atacatcata aaaaagtaat gtcatcaata acaccatgaa aatatatatt attatcataa
    66901 ctaaagttat ctctgagttt aactcagata ttccatataa aacaataagt atacttgcta
    66961 gaattaatgg tgatgaacca atattaatat tttcaaatgt taacctaaat agtgggtcta
    67021 atggttttgt aatatagtag tctaattctc cttcttggat ttttcgtgga atatcataaa
    67081 taccaaaaaa gaaaatcgtc atatttatcg catttattaa tgagaaagtt cctataaata
    67141 ttaacatctc tccttgttgc catcccccta ttgagtctac ataagaatat atactattaa
    67201 acattagaag ttgtaatata aataatgaac tatctacaaa aaatgctcca aaaaaatcaa
    67261 atctaaatac catcatcttt gataatttca tttttaataa cataaatatt attttcaaat
    67321 tttttttcat catataccca ccccatcaaa taatgttctc attcttttat acataacttt
    67381 atttactaca gaaaaaaata aaacccataa tgctagaata attaatcctt gtattgcctc
    67441 attgctgttt ctacctatta gtaacataga tggcaaatat gttgtataat aaaatggaaa
    67501 taccttcata actgttacta tagtttctgg taagagtaca agtggtatca ttgttcctgt
    67561 aataaattca acaatatttt caattatcat tctaaaaaaa ctaatctcaa gaaatttaaa
    67621 tgacaaaatc ccaataaaga agtggagttt catcataaaa ataaacccta gaaaaatcat
    67681 caaaattgaa attaatattt gaactggatt tgatgtaaag gcaaaatcta ttttaaatat
    67741 aaaaatccat acaaatgcag aaatcatatt aaatacaaaa taaaaacatg tcattccaaa
    67801 atttttagca ataaaataat tttgaacatt aattggaata atcatgtact ttgaaaatgt
    67861 gcccaatttt acacgattac atatctcttc actggtactc tttgacatat caatacctgc
    67921 taaaaatgag cttattatat agtaagacaa catagagtta aatgtaaaac cagagactat
    67981 tttattttca ccaaaaattg ctttccataa aatataagca aataaaattt ttacaatcgt
    68041 aaacaccata ttaaccacca catcaaatct ccagataagt tgcactttaa agttaatttt
    68101 ggctacttca taataccttc taatactctg tttaaattta taaaacattg aataatttga
    68161 acttgcttca ttatagttgc tcataatact catcacttcc tttcttatat attctctcta
    68221 caatactacc tatatcttct tcttcaatca ttacatcttt aacatcatat ttatcaaaaa
    68281 tccacttaat cgtttcattt cctctttctt ttggcacaat tactgatgtc ttatgatttg
    68341 tttgttcaac aactttacaa tcttttggaa atacaatgtt agtttcattg gaaaaactaa
    68401 ctgttatttt tttatatttt tgaaaatgat taaatagttt ctctgtagaa ccatcatata
    68461 ttttacggct attttctaca acaatacttc tactacagag actcttaata tcttccatgt
    68521 aatgagaagt aagtataata gtagttcctt ttgtttcatt tacttctttt aggaaatacc
    68581 taatttgttt ttgggctata gcatctaagc ctatagttgg ttcatccaaa aataatattt
    68641 ttggattatg tagaagggct actattagtt ccattttcat tctttctcct aaagaaagcg
    68701 tcctaacttg aacatttaaa tagtcagata cctcaaataa ttcgataaag taatccaagt
    68761 tttttttata ttcttcatta gatatatcat ataattcttt aaataaaaga aacgtatctg
    68821 ctggtgtcaa ttcaaagaat agttgacttt tttggcccat aacaacagca tattgttttt
    68881 taaaattatt ttctaatttg ttagggtaat aacccataac agatatttct ccagaagacg
    68941 gtgcaataat accagttaac atcttaataa gagtagtttt gccagctcca ttttgaccta
    69001 ttaatccaac aaattctcct tcttctatct ttaaatcaaa tgacgatata gctgtttttt
    69061 ctgtatattt cctattaaat aaagacttta cactccccat aaatcctgcc tttttctcaa
    69121 atcttctata agatttagtc agttcattaa gttcaattat actcatttta actacctcca
    69181 tatttcataa tttatataaa aaaagtccac aggtatatat ctgccttttt ctgtgcttat
    69241 atttaacagc acaaaaacag aaaactcctg tggactagaa aaattaatgc tctctatttc
    69301 aaaatagtta tcaaaataat actatacaaa attaataaaa gtgtagcaga ttaaagccta
    69361 ctacaccata atttaacaaa gtaatatata ttttaaatac tatttgttgt catatgtcag
    69421 ttatctataa aggcagaata agacacaaaa attaaatgta ttaaaaatac acttaaaatt
    69481 tctgattata cagaatatat gtgtctccaa ctatttaatt gttggttacc attatataac
    69541 tccgacatca aggcactcct ctcataatat tattattgat atcatatcat aaaggttatt
    69601 tatgttcaag tatggattta tatactaata catttagctt atttcttcag ggttgaattt
    69661 aaatttcatt tataatattc gtttataaat caaaaatata atacgtatat taaaactggt
    69721 tattttactg taatattttt attgtaaaag atatactttt acctatacag gatgtaattt
    69781 ctttagttct atattataat aatattgtaa taagagttca acttataata cagtaaaata
    69841 taaactgtaa atcttaaggg ggtaatctat ggaaaataat acaatacaaa aacaattaag
    69901 agatttatca aaaaaaattt ggcatattta tattttaaat ccagaagaag aaaaccttaa
    69961 atttattatt tccttattag ataacaacct tgcattaatt ggaacaggaa aacatgaatt
    70021 ttacgaaaca ttagaagaat ttattatagg tcttgaaaaa gaccaaacag aatcagagca
    70081 aatagacttt gagattatag atgagtggta ttcatgtacc aaagttacag acgaagcttt
    70141 tatagtatat ggtactcttt gggtaataga aaaagattac ctagaaaaag atatctatgt
    70201 agaaatggat actcgattta ctatggtata cagagttaca gatgatatga ttaaacttat
    70261 ccatgttcac cattctattc caaactttga ccaaatgaaa gatgagtatt accctaaaac
    70321 aataactgaa aaagcacaag aagcactagc aatggcaaat gaatttaaac taaaatcaga
    70381 aaaagacctt atgactggac tatacaatag acattttttt gaagtacaca taaaagaaat
    70441 gcttaaaact gtttcatatg gatactttta catctttgat ttagataatt ttaaacaggt
    70501 aaatgatatc tttggtcatg ttcgaggaga tgaaatacta ataaagtttt caaatatttt
    70561 gactaaagta ttcgtaaatg atgctattat tggaagactt ggtggagatg aatttgctgt
    70621 ttttgaatat agtaatcaat caaaagagaa tgttgaaaat aaatcaaaga aagttttaga
    70681 attatgccta gagagtaatt cttgttctat aggtatatct aaattagaaa ataaatctga
    70741 tactttccag tctttataca aacaatcgga ttatgctttg tattattcaa aacgaaataa
    70801 taaaggaaac tttagttggt tttagtacaa aagatattaa aataggcaaa tttattagag
    70861 tatcttgtcc tatatactaa taagtaaagt aaacaacaag ctatctttgc atatatttat
    70921 ataaaccaac tattcttaat aaaactacaa tagtcaacat gaccactatt atagaatata
    70981 ataaactaaa aacattatta acatgattaa tattatattt taataatttt atttttaaaa
    71041 gtaagtccaa aatgttatat tttttgatta aaactgatgt tgatataaaa aattttactt
    71101 aaaaaaacac ttagaaaggc tttataaaga gccttttttg cttttattga ttaaattttc
    71161 atataaaatt ccttattaaa tttcaaatca ataaaaaaag gctccataag aagcctcccc
    71221 tatttttatt gattaaatcc taatatagac aatgccttag catcatagta agtagtcatc
    71281 tctcttgttg catcctttaa tttacggtaa tcaaagtcta gtgctccacc aaaagctgat
    71341 atttcagacc catcagacct ataccatttc ccatcaattt gtatatagtt ccaagcatga
    71401 tttaatgatg gatttaatat agatagtgaa tccattccca ttaaccttgt taataaatga
    71461 aagctacttg caaaacttcc acatacacca cgtttatcaa ccagattacc atagactatg
    71521 ttacaatatt tagagtctac atattttgct tcggttacca attttgcagc tctattagct
    71581 ctttccatct cagatgcatt tctccagtca aaactattta aaaaattcct gattactgta
    71641 agtgtatctt gagcttgttt gtaagaaatc caatctccat cggctattac ttctataggg
    71701 tcaagttttc caaagcctat tctctgatat gagctacctg acaatgctgc tgcataaaat
    71761 cctagccctt ccataccctt atttatataa taatatttac catctgctcg aagctcaact
    71821 ccatttggat ttcctccata gagtaaatta aacttatttt tttaaaacat attgtttaaa
    71881 tcagtacatt tatatgtttt ttttgttcat ctgttttatc aaatatatta gtctttgaat
    71941 tttgtttgta ttcttcagca tctttatcta acttttctat tctcgactca agtttcatta
    72001 tttcttcttg tgttaaattt ataaaatttt taagcatatt ttcaagctct tcacgagttt
    72061 tacctactaa agataagtcc tcagatactt tctctttttt attagaatcc tctttataat
    72121 cctttttttg ttctaactct tctaattttt catcatttaa tatttcttct tcaatttttt
    72181 cattagactc tttagtgatt aaagattctt tttcatcatt tatatttaga taagttgaat
    72241 tttcatctaa cattgtactt ttatttttat cttctataat gctattttta atacctattt
    72301 ctatattaga aaagttatta gttgtttctc ttatttctga tttacataag ttcttaattg
    72361 cttcatttat ttttttaata taaacctctt gtctatattt taaatctcta attctatcat
    72421 taagttcttg cttttgtttc ataatattag ataaataagt gtcttttcct acagtttcat
    72481 ttttcttaac catactttca tttattcttg tattatttat attactttca tgtctaaatg
    72541 aatattgact tctatattga ctagatattt tcatttattt tacctctcta aaataaattt
    72601 atgtttataa aaaccaactt aacttaatta tattttatca tcaaaagtat acatttacaa
    72661 atattagtta atagttttat aggttcgagc attattttca acaaaaaatt tttattataa
    72721 attaaaacaa taatttttat aaatatctta tttgtatttt ataattcata tatttttact
    72781 ttataaatta gcaatattgc agttttgctc ttaagaaaca tctctatcat acataagcat
    72841 atactctatt atgtattagt ataaatatgc cttttcttat cttacataag acctctttat
    72901 aaaggagact atcgtaataa atatgtatac attatcacat atatatatca tcatataaaa
    72961 aatcaaactt tattaaaaaa attaataaat tgctttaaat aataccacaa accaaatttg
    73021 ccatcaaaat cacattaaag taacaaatta atggcaaatt taatacatta atagtatata
    73081 gactcataga atgaacaaaa aaactacact tatcttctaa tcgtcttatt tatttttgag
    73141 atatttttaa atttcttttc tttttttgct aagtattcgc ttttattgtc tgcaaatact
    73201 gcttcagttt taagcctacg ataggattcc catcttttag gcgaaagttc ttgatgagca
    73261 atagcttccc agatagcaca gcctggttct gaggtgtgag tacaattacg aaaatgacat
    73321 tttccgaaat aagcttctat atctgcaaaa cttttatcta aaccttctga aacatcccac
    73381 attcccaact ctctcatacc tggtgtgtca ataacaatac caccacctga aattaaaaat
    73441 agctctcgtc tagtcgtggc atgtcttcct ttatcatcat ctatgcgaat ttcctttgta
    73501 tttaaaaatt ctcctcctag cagacaatta attaatgaag attttccaac tcctgaagag
    73561 ccaagtaatg caacagtaca gcctgatttg atatacttag aaatctgttt ataaccatct
    73621 ggctctatag atgaggtaac tactacatct acacccaagg ctatagaatt aactacttgt
    73681 aatttacgat gcacattgtc acataagtct gatttagtaa gtactactac tgggatagct
    73741 ccactttccc atgttaaaga cagatacctc tccaatctat gaatgttaaa gtccttattc
    73801 agtgacatgc acaaaaaaac aatgtcaata ttagctgcaa ccacctgttc ctcatttacc
    73861 tttccagcag ccttacgcac aaacaagctt tttctatgaa gcacatgatg aataatagca
    73921 ttaccatttt tattattgca acgatccaac ataacgaaat caccaactgt gggaaaatca
    73981 gattgtatag tagcctcaaa acgcagtttt cctgaaacct ctgcaaacag tacaccattt
    74041 acacatacag cttgataaaa gttcttttcc tgcgagataa ttcgagcaag gtataaatcg
    74101 tgatattcca tactttgagt aataaaattc ctatttagac catagtcttg taaattgatt
    74161 tgtttcatac cattcattct gtttcctcct tttccaactt ttcaatgatt ctttctagtg
    74221 ggaaaggggg ctgtgccagc ggttttaatg caattgacat taatttcact gaattatcat
    74281 cagctgcaat acgattagaa ctaagatgtc cacagcgtgt acaacgatga ataattgccc
    74341 actcaccatt ttttctcacc cacactccaa taggttccat attagcatca caatctgcag
    74401 cacggtcacc aggaatgata tacacatgaa gactatgtaa acaatgtgga caatgatttc
    74461 tatgttgtgt accagctcct tcaggaacta caaggcaacc acaatttttg caaataaagt
    74521 tatccataca ggaattttcc tgataataag ctcgttttct atttttataa ttcattttta
    74581 tttcctccgt atcttgtatt ttctacaaaa aaagtccaca ggtatttata tctgcctttt
    74641 tatgtggtat acatatttac ctacacaaaa acagaaaacc cctgtggact agaaaattta
    74701 atatcttcta tttcaacata attatattca aaataatact gtgtaaaatt aataaaagtg
    74761 tagcagatta aagcccacta caccacaatt taacaaagta atatgtaata ttattatttg
    74821 ttgtctaatg ttagttatct ataaaggcag agtaagacac aacaatcaaa tgtatcaaaa
    74881 atacacttaa aaattctgat taaacagaac ccatatgcgt ctccaactat ttatttgttg
    74941 gttaccatta tatataactc tgacatcagg caagacactc cttcactaat aattattatt
    75001 gaaattttat cataaaatat aagtatgttc aagtataatt taatatattc atatatttat
    75061 gtttgtctca ttttcttatt ctataaaatc tagtggtatt ttaaaattta atgttcacct
    75121 agtattaata ataaaaatta accgctatta tttgttttct cattttatgc ctattgctca
    75181 atttatctcc cttaaattaa taacaactgt cttttcatac aaagcctaca atcaagtttt
    75241 tccatatatt ctacatgcat aatctatttt tttgatataa aataacattc atatttataa
    75301 atttatttaa ttttcaaata agtatattga ataataacca attctattgt attattgtaa
    75361 ttgtagaata aaactaaatc ggcaaaacta gagaaattta gtgacgcaaa gctataggga
    75421 ctaacgctta taaaataaac tatgagttat gtcagccagt tgccaaaaag agatattctt
    75481 tttgttttta tgaaagtttt ttagggggat aataatatat atgtttagag ataaaatgga
    75541 tagatgtaca catatgttga ctgcttatat tggtagttca tatgattatt gtgattttat
    75601 agatacacaa ctagatgatt ttatactaga gtacggagaa aatgtggtag aatcttgttt
    75661 gcatcaagtg atggtattag taagtaagta taattaaata gatttggttt tctagagaac
    75721 cctttttagt tttatctact ttaaatagtc ttatgttaga aagctaatta agatagattt
    75781 ctagtattca taattttatt ttctatttaa aatacatata ataaagatgt aaatttgtat
    75841 caaataataa atatgagaac ttaaattctc ttatctatgt gaaaataaac atctcttaaa
    75901 atgaaattct gtaaacataa atgatttttt agtttgaagg attagattaa caaaattata
    75961 aatttgcaaa taagctatat taaaaaatat aataattttt tatataactt attcttttat
    76021 aacttttaat tttaaaagag gagaatgtat ataagagtat tcaatgtact agaaaaaatc
    76081 aaaagaaata ttagaagaaa tggatattga gtaatcaaat aaaagatttt gatattacaa
    76141 atgatatgtt tcaagaaagc attcctatca caacaaaaac tattcttgaa gacatgcctt
    76201 caaatgatga attaaatcat gttttttcaa aaggttgtga acgaaaaatg aaaaagagaa
    76261 aaattgtatt aatcacacta ctattaatag gtgttttgtt attaggaagt atcctatata
    76321 atcttttttt agtaaaagca gctaatattt caatgctaaa ggaatcttgg aattttgata
    76381 taccaatacc taacaaagaa attgaagtat ttgatactca agatagtatt aatggagatg
    76441 gacaaagtta ttttattcaa ggattttctg aaaaaaattt caaaaaagtt tttaatttaa
    76501 aaggtggtat agttgtaagc aaagataata ttaatgaaat agaaaaatat attgataaat
    76561 ttaaaagaga ttctgttaac attaataaaa gtaataaaaa taaaattgaa gaagatttta
    76621 aaaaatataa gttagaagtt aaaaaagatg ataagtatat atataagaga aattatgaaa
    76681 actatgtagt tttaattata aaaaaagatg aacaaaaatt atacagttta atatggaatc
    76741 agtaggtaca tatgtattat taagaattat aaataataaa aataaatttt agtcaatcta
    76801 caaaaacctt ttaaattgtc tggaaatcac ctcctcattt gttataaaaa catacaacaa
    76861 atgaagaggt gattttatgg tttttaaaaa aataattata agtggatatg tgctttcaca
    76921 tgtttatcaa catttgtaat gcctatattt gctaatgaat tataatataa aaatattaaa
    76981 taatattcaa ctatagatta tgtaaattat cctatgaaaa aaataagttg tataaaatct
    77041 ggcaactgta gattgactat ttcttttaaa attataatta taataagttt tatagaatta
    77101 aaaataaaac tttagagatt tttgataaca ttgtagacta aatttgccac cgaaattact
    77161 ttacagtggc aaatcggtgg caaatacaat atattattag tatataatct atataaacat
    77221 tactattgct tgattatctt agctacagtt tccacatgtg tagaatgagg gaacatatct
    77281 acaggttgtg cctcaacaca tttaaatccg tgaacattta gatagtctaa atcccttgct
    77341 aaagtagaag gattacaaga aacatagaca attctttccg gattcattga aacaatagtc
    77401 tctaatacct tttcgtcaca tccctttcta ggtgggtcta caactactac attggcagtc
    77461 ttaccctctc tatacatctt aggtacaatt tcctctgcct ttccaacata aaattcagca
    77521 ttatgtatat tgtttaattt agcatttatc ttagcatctt ttatggcatc atctataatt
    77581 tctattccat aaaccttttt agccctttgt gccaaaaata aagatattgt acctatccca
    77641 cagtaaatat caaaaacagt atcagtatca tttaaatttg catattcaag agccttatca
    77701 tacaatactt tagtttggac agggtttact tggaaaaatg ataatggtga aatctcaaac
    77761 actaagtcac ctatataatc gtttattttt ccatctccat atataactat attttctctt
    77821 cctagaatag cattcgtatc tttttgattt acatttacaa ctaaagtctt aaatccaggt
    77881 atattttcct taagcactga agctaattct ttaagatatg gaagtttgtt tccatttgct
    77941 actaatacaa ccattacttc tttagttgta aaacctattt ttgttactaa atgcctaatc
    78001 aaccccgtgt gagtcttttc atcatatata cttaccttat aggctcttat atatgttttt
    78061 attattttaa caattttatc atttatctca tgttgtatta cgcatttttc tgtcgatatt
    78121 acatcatgag tcttcttttt atagaagcca ataattggaa taccattatt cttttgtatt
    78181 ggaaattgtg ctttatttct atatctatat ggattatcca ttcctatagt gtcatgaact
    78241 tctacatctt ctaacttacc tattctcgaa agtacttgtt taacttcatt tgttttcatt
    78301 tcaagttgtt tattataatc taagtcttgt atctgacacc ctccacaatc cctaagattg
    78361 tcactacaca ctcttttcac cctgaatgga gacttttcta ttatctcaac aatatctccc
    78421 acagcataat ttttctttac tttattaatc ctaactttaa ctttatcatg tattaatccg
    78481 ccctctacaa aaactgtaat accattgtac tttcctactc ctactccgcc ttgaccaatg
    78541 tctactatat ctacaatata catctcgttt ttcgaaagca taaatcaccc tccaatcaat
    78601 ctattatatt taaatcttta caaacttttt tctttaaatt tatattaaaa tattgctatt
    78661 aattaaacta tattttttac taagctacaa tattttattt taccaaaaaa aaaggagctt
    78721 ataaagcccc ttagtaaata aatttattat ttttcttata aaactctagt tgaacctcta
    78781 tataccacgc ctcttgatgc atccacagtt acaacttctc catcttttac tagatttgtt
    78841 atatcagttg cagacacaat aactggtata tctaaattta tacctacaat agctgtatgt
    78901 gatgtcattc caccattctc agttactaca gctcctgctt tttctatata attgttcatt
    78961 tcagcatcag tagcagtaga aacaagtatg tcgccttcat taaagtctac acaagcattt
    79021 ccattcttta ttatacgaac tttaccttct actgtttgag tacctacacc tataccttgc
    79081 acgatttctt cgcttattac atgaaccttt attaaattag tagttccact tactcctact
    79141 ggtactccag cagttataac tactaattcc ccattatcta tataatcagc ttgtctagct
    79201 gcctcaattg ccttttctat aacttcatct gtatttcctg caacagaaga cttaactgga
    79261 tatactcccc atgtaagagc taatttattc atagtctttt cattatttgt agtagctatt
    79321 attggagatt ttggtctgaa tttagatacc attctagcag tatatcctga agaagtagat
    79381 gttattatag ctgatgcatt taaatctact gctgttgtac aagttgcatg gcttattgca
    79441 tctgttacag taacattgtt agtaccattt tcctttagta atctatcata atctaaagtc
    79501 tcttctgttc tttttgctat tgtagccatc atttttactg cctctacagg atattttcca
    79561 gcagcagttt ctccagataa cattatcgca tctgttccat catatatagc attggcaacg
    79621 tctgtaactt ctgctcttgt tggtcttgga tttcttatca tagaatcaag catttgagtg
    79681 gcagtaacaa ctggctttgc taattcatta cattttttta tcatcatttt ttgaactatt
    79741 ggcatctctt cagttggtat ctcaacacct aagtcacctc tagccaccat tataccatca
    79801 gaaactttta atatttcatc taggttctct acaccttctt ggttttctat tttagatatt
    79861 atttgtatat cagttgcatt attgttctct aatacttctc ttattgctag tacatcagat
    79921 gcctttctta caaaagaagc agctatataa tctattcctt gacttattcc aaactctata
    79981 tcacttatat ctttaggagt tattgctggt aaatttatct taacaccagg tacatttact
    80041 cctttatgat ttttaactat tcctgaattt tcaacaacac aaactatatc ttctccattt
    80101 atttctttta ctcttaagcc aactaaacca tcatctatta gtatagaatc tcctgattta
    80161 acgtcttcag caagaccttt atagcttact gtacacattt ctttagtccc cataatatct
    80221 ttcatagtta tagtgaactt ttgcccttct tctaaaaata cctctgggtc ttcaaagtta
    80281 cctgttctaa tttctggacc tttagtatct aataatatag caactggctt atttaatttt
    80341 tctctaactt tctttgccat atcaattctt tctttatgtt cttcatgcga accgtgagaa
    80401 aagttaaatc tacacacatt tagaccattt tgcataagtt gagttaaaac ttcctcactt
    80461 tgtgatgctg gacctagtgt acaaacaatt tttgtcttct ttacattatt taacatattt
    80521 gctcctcctg agatattatt ccacagattt atttttaata ctaaaactta tatagataat
    80581 atttttgcca tctcataagc ttctttatca aatactttct tttgagctaa agcttcactt
    80641 atttctaaat caattatttt gttttctttt attcctacaa ctctagctga ttttccatct
    80701 aataataatt ctactgctct tactccaagt ctacttgcta gtattctatc agatacagtt
    80761 gggcttcctc ctctttggac atgccccaat acagtgactc ttaaatctgc tcctgactct
    80821 tttttaagtt ccttttctaa atcactagca cttccgactc cttctgctaa aacgattata
    80881 ctatgtctct tacctctttt ttgagtagtc tttaatctta gagcaacttc atctactgta
    80941 atttctactt ctggtactat tatagtttcc gctcctcctg caagacctgc atataaggct
    81001 aaatctccac agtgtcttcc cataacttct actatgttaa ctctttcatg agatgatgat
    81061 gtatctctta tcttacctat agcatctata atagtattca tcgcagtatc aaatcctata
    81121 gtataatctg tatatgctaa atcgttatct atagttcctg gtatgcctat agctgggaat
    81181 cctaagtcac taagtttttg agctcctgca aatgaaccat ctccaccaat tacaactaag
    81241 caatcaattt tatacttttt aagaattttt actgctttta atctaccttc ttctgtttta
    81301 aattcttcac atctggaaga ttttaatata gttcctcccc tgtgtataat atctccaaca
    81361 gaagataagt tcatttcagt taaatcttct tctagtaatc ccttatatcc tctattgatt
    81421 ccatatactt tgcatccata atatattgct gatcttacaa ccgctctaat cgcagcattc
    81481 attcctggag catctcctcc acttgttagt aatcctatag ttttcatttt ttacctcctt
    81541 ggattttatg tcaatttttt attataatca ttgttattgt attctaatgg actttttttg
    81601 tccctatatc actttttaat cccatcaaga ctaaaaaaat taaatgtcct taaatgtcca
    81661 ttttgtgata ttatatcaca aaacggacaa tatttttcat attattataa tatatttaga
    81721 tttttatata aaaaatcaag cttttacttt tatgttatct ttaggaagta actcttctaa
    81781 gttatttata aattcatcac atatacaagt caatgccccg gtcattttat atgctttacg
    81841 tttaccattt atattttcat ccatagggta taagtatata ctgtcattac ctggatattg
    81901 tttggctatt tctacaatat tattagttgt atcggtatca gacatactat ctattttcaa
    81961 atacaatttt ttaccacttt ctggcttaat attttctaca tttctagttc ttcctgaatt
    82021 gtagtttcta tctgcaaagt cagtatcatc atttatatct tttatctctc tagctataag
    82081 ttttgcattt tcgccttctt ttatacttaa tgttcctttt acatatatta tattatcttc
    82141 attcaaaatg acattatact tttgtaataa ttgaggaaaa actattattt ctatagcacc
    82201 atacaaatct tctaattcaa taaatgccat aatttcattt cgttttgttg ttttaatggt
    82261 tttagttaca atcattccac ccattataac atctgtttca ttcatttgta ggtatgactc
    82321 ttcttcctct tttaatgaat ttaattttcc attatccata gatgtttttt cttgtagttc
    82381 tttttcaaat tgtgataaag gatgtccact tacatacatt cccaagactt ctttttcaag
    82441 gttaagtctc tctctttctt catactcttg ccttttaggt aaactgtata tttgttgaaa
    82501 atcactatct tcctcactat ctccaaaagc atcaaataaa gaaatttgac cttgaacatt
    82561 tttctttcta tccatagata cactttctaa taaactttca taaccagcca tcaaactagc
    82621 tctattttca cttatattat caaaagctcc acattttatt agactttcta ttactctctt
    82681 atttgtatct ttttggtcta atcttttgac taaatctact aaatctacaa ataatccatt
    82741 agattctctt tcagcgatta tattgtttat tatatttacg ccaacatttt ttacggctgc
    82801 tagaccaaat cttatattgt caccttcaac tgaaaacttt gaaaaacttt tgtttatatc
    82861 tggaggtaat acatctattt ctagtgcttt acattctctt atatactcaa ctaccttatc
    82921 agtatttccc attacactgg ttatcaatgc tgccataaat tcaactggat aatatgtttt
    82981 tagataagct gtctcatatg ctaaaacccc atatgcagct gcatgtgatt tattaaatgc
    83041 atatctagcg aagtctatca tatcatcaaa tattttatta gctatttcct cttctacacc
    83101 atttctgata caccctgcaa tttctatatt accatcttca tcaaatttac catgaataaa
    83161 atattgtctt tcttcttcca tcacgtccat ctttttctta ctcatggctc ttctaactag
    83221 gtcacttcgt ccgtaactat aaccacctaa atctctaacg acctgcataa cctgctcttg
    83281 atataccaaa caaccatatg taacttccat tataggcttt aatttttcat gtagatatgt
    83341 tacatctttt gggttgcttt tattttttat atatgcaggt atagaatcca ttggacctgg
    83401 tctaaatagg gatattcccg ctacaatatc ttcaaaattg tctggtttta gctgtttcat
    83461 aaaacttctc atgccagcac tctccaattg aaacacccct agtgtatttc ctgatgaaag
    83521 catttcatat actttcgggt catcataatc catctttgaa aagtctattt tttctgtgta
    83581 attttttata actctatttt tttctattaa gtcaagagta tctcttataa ctgtaagagt
    83641 tcttagccca agaaaatcca tctttaaaag cccaagttct tcaagtgttg tcatagtaaa
    83701 ctgtgttgtg attgcatctt gatgtttgta caaaggtaca tattcatcta cgggattttt
    83761 tgatataaca actcctgctg catgagtaga agcatgtctt agcattccct ctatctgttt
    83821 tgatatattt attatttctt ttgtttccgg gtcttggtca tacaattctt taagattagg
    83881 atttgtatct agggccttat ctattgtcat tcctaaggca aatggtattt ccttggctac
    83941 cttgtcaact ttattgtagc ctatatccaa tacccttcca acatctctta ttgcagcttt
    84001 tgcacccatt gttccaaaag ttattatctg ggctacatgg tcatcaccat attttctctt
    84061 tacataatct ataacttctt ctcttctctc ataacaaaaa tctatatcta tatctggcat
    84121 ggatatacgt tctggattta aaaaacgctc aaataataga gagtacttta ttgggtctat
    84181 atcagttatt ttaagtgtat atgctactat cgaaccagct gcactacctc tacctggtcc
    84241 tactataata ttattttctt tagaaaaatt tataaaatcc caaacaatta aaaaatactc
    84301 tacataaccc attttttcaa ttacatctaa ttcataattt aatctctcta gtatctcatt
    84361 gctaggatta tcatatctct cttttaatcc attaaaacac aactccctta aataagtttc
    84421 tggtgtatat ccttctggaa catcatactt aggaagatgt atagtattaa aatcaaactc
    84481 cacattacac atatcagcta ttttcacagt attgtcaata gcctctaatg cgtatggaaa
    84541 taattcttcc atttcttctc ttgattttaa gtaaaactca tcactaccaa atctcattct
    84601 atttgggtca tttaatgttt ttcccatttg aatacacata agaacatcat gtattttcga
    84661 atcttcttta tttacatagt gaacatcatt agtagcaact agtggtatac cagtctcttt
    84721 tgataatttt actaaaccag agtttacttc tttttgctca ggtaaattgt gatcttgaat
    84781 ctccaaaaag aaattttctt ctccaaatat gtctctgtag tcaagagcaa attgttttgc
    84841 tttttcataa tttctattca ttaaagcacg tgctacatct cctgcaaggc atgcagaaag
    84901 tgctataatc cctttgttat gttttttaag ttcttccatg tcaactctag gcttatagta
    84961 aaaaccttct acgtatgaag ttgaaactat ttttattaaa tttttatatc cttccatatt
    85021 cttagctaac agaactaaat gtccttgata tttgtcatag tttgggtctt tatctctcaa
    85081 tccacgtgca gctgtataga cttcgcaccc tataattggc tttattcctt cttttatagc
    85141 tgttttgtag aaatctataa caccaaacat acaaccatgg tcagttatag ctattgagct
    85201 catgtttagt tccttagccc tttttataag ttttttcacc ctcgaaaacc catcaagtaa
    85261 actatactca gtatgtacat gaagatgagc aaaatctttg ttcattaaat cacctcctgc
    85321 tttataattt taattttacc acaaatatat gtcctaaaac aaaaacagag acttttatct
    85381 caaaatagga attaacttca acatatacca ttatatgtta taaattaatg cttattctga
    85441 gattgtcccc tcaatttatt gctatgattt ttttttcaaa tctgttgcaa tttcttctat
    85501 ttttctaagt ctatgattga ctccagattt tcctattggt ggttctaaca tctctccaag
    85561 ttctttgaga gtcatatcct catactcgat tctaatctta gctatctctt gtaaattttc
    85621 tggcaaactg ctaattccta tagtctcttg tatgagctta atattttcta cttgtcttac
    85681 tgctgcattt actgttttag aaaggttagc tgtctcacaa tttactatcc tgtttacatt
    85741 atttctcatt tcttttacta ttttagtatt ttgaagactt aaaagagcgt ggtgtcctcc
    85801 tataatactc aacaaatctg atatttgttc actctctttg atataaacaa cgtgattatt
    85861 ttttctagcc acaattttac tattaaaacc taaagagttt ataagttctt ttagagaatc
    85921 tgcaaactcc tcattattag ttacaaattc catatgatag ttcttttctg ggtcgcttat
    85981 agaacctcca ccaagaaaag ctcctcttat gaaagctctc ttacatcctt catgcttaat
    86041 taagttctct gaaattttgt ttatagtaaa aaagccttct ttatcttcaa gtatacctaa
    86101 cttttttaat aacatttctg aacccatttc gcttgttacc attaatacat aactgttatt
    86161 tctctttagc atttgattct tatttactga gattgtagta ttgatattaa aattcttttt
    86221 taataattta aatactttac gggctattga atttaactct gttgttatct ttagatttag
    86281 cttcttatat ccaacgattt gtatacttcc ccctgattta actagagctg ataattcagc
    86341 tatattacaa cattcattcc cagatataac tcttgctagt tcatttttgg tttcagttga
    86401 aaaagacata tctatcacct attaactaat ttttctttaa cctttttttt atttcttgta
    86461 aggcaacctt tattatctcc ttttcatcat catacctagc taagtctact actctatcta
    86521 ggtggataaa tttagcatca ataaagcctt cctctttttg tggaatagta tccatattct
    86581 ttgcttgcat caaataccaa aaaactgttt tatgaactgc tctattttca tcccagtttt
    86641 ctttgaatgt atagtgtatt tcacctaaat atttcaatat atctgctttt actccagttt
    86701 cttcacttac ttcacgtaat gctgcctctt ggttattttc cccttcttct acttttccct
    86761 tgggtaacac ccaatctcca ttgaacttcc ttagtaaaag aatcgtattg ccaaacagga
    86821 ctacaccacc agcactaacc tcttctctca tcgatgttca ctccttaaaa ctaacataat
    86881 gataaggatt tctacacaat tttttaaaat ccttttttac taacttttgt tgtaattatg
    86941 atttagggct aactcaataa ctatgttaga tatatacttt gcatcatgtc ttatataatt
    87001 attttttatt tcaattaaat tcttctctac agtttttata cccatctctt ttaatttatc
    87061 tttttgcttt ttatctaaca agacttgctc tgctccatct tgtttatata agtcaagcat
    87121 ttcttctggc aatatctcat tgtttgcgat tacataatct attaaattct catcagtgtg
    87181 ttttactata gcattaacat gctctaatac attgtaccct tctgtctcac ctggttgagt
    87241 cattatattt gctatatata cttttggagc tacagacgat ttaatagcgt ctacaatccc
    87301 ctctacaagt aaattgggta ttatacttgt atataagctt ccaggaccca taattataat
    87361 gtcagcatca taaatagatg caataacatc ctttaatggt ttgacatctt ttggatttaa
    87421 aaaaatttta tcaatagagc ttttttgaat ttttgactct tcaggtatac tagattctcc
    87481 atttattata ttgccatttt ctaatttggc aactaaattt acatcttcca aagttactgg
    87541 taaaactctt cctgttatag caaaaatttc acttaattta tatacagctt tttcaaagtt
    87601 tccatacaac ccattcatag cagccaaaaa caaatttcca aaactctgac cttttaaaag
    87661 cccttctgta aacctatatt gcataacttc attcattgtt ggctctatat ttgcaagtgc
    87721 taataaacag tttcttatgt ctcctggtgg gagcattcct aagtcttctc tcaatacacc
    87781 tgaacctcca ccatcatcag caacagttac aattgcagtt atattttgcg tagtgtgttt
    87841 aagacctctt aaaaataccg attgaccagt acctccacct atcacaacca catttggttc
    87901 tctattttca acaatagacc tttgaaatag ttttactttt tcattttttg cttttttata
    87961 tataaataac gatacaatta atgcaatcca acctaaaatt cctacaataa taagtaattt
    88021 agtcatgttt gcctccatta tcgcaacata gagtctctat gtttctttac aactctatat
    88081 cccttattag ataaatcctc cgctataaga tttgttatag taactgacct atgtcttcca
    88141 cctgtgcatc caacaccaat tactagatgt tgttttcctt cctctatata ttgaggtact
    88201 aaaaaatgaa tcatatctaa aagtttcaca taaaattctt cacttatttt agaattcata
    88261 acataatctc taacttcttt atcatcacca gttttagctc ttaactcttc aacataatag
    88321 ggatttggaa gaaatcttac atcaaatact aaatctgcat cagcaagtat accatgttta
    88381 aatccaaaag atactacaga aatagttagg tttggattat cttcaccaga agaatatatt
    88441 ttctttattt cttccttaag gtctttaggt ttcatgttag ttgtatcaat tatacatgta
    88501 gataactcct ttaaaggttc cattatcttt ctttccattt ttataccttc tggaatctgc
    88561 atatcttttg ccaatggatg atttcttctt gtcattttat atctctttaa caatacatca
    88621 tcattacaat ccaaatatac catttcatat tcataatttt ctttttctaa ataatttaag
    88681 ctttcatgaa gcgcttcaaa aaactttctc cctcttatat ctatccctag agcaacttta
    88741 tcaatacttg aatttggttg ataacataat tctgcaaatt tagttatcaa agcaggaggt
    88801 agattatcta cacaataaaa tcccatatcc tctaaagctc tcattgtctc actttttcca
    88861 gatcctgaaa gacctgtaac tataacaaat ttcattgcta actcctccct tttatcttat
    88921 gtttattata ttataatgtt ttctactaac gatatatcca gattagagtc agatatagtc
    88981 ttcatagcta gttcaaaatc accaactctt tctggacaat gtgcatctga gcctattata
    89041 aatttatttt ctagcccttt tattttattt aattgattta cattcaaaaa agaatggcta
    89101 ctgtttatct caagtctagt atttgtcttt tttgctgtct ttgctacttc ttctatatac
    89161 acatcgcctt tatctcctgg atgagtaatt ataaaaatat cattattact tatcgcattt
    89221 attacagctt ttgtattata ttcttttgct ttttcagttt taaaaatata gttattacaa
    89281 tgatttaata agcttcttaa tgatgttgga gtagaaccaa aatgatatcc agccataata
    89341 taatcaaaat ctctaataaa tttatcatcc atatctatat ttcctttatc atctaatatg
    89401 ttacactcca tacctaaaag tatatttata tcagtgtact tatcatttaa ataatctact
    89461 tcttctctca ttttgagaat atcttttttc tttacaccat atgcaatatg tttataacta
    89521 tggtcagata ttcctattgt ttttattcct ttagaaatgg ctacctttac attctcctca
    89581 atagtccctt tgccatgact atataatgta tgtgtatgat aatcagccag tattttcatt
    89641 tgttaatcct ctccaagtat tttgacttct tcttccaaca taaccccaaa cttggcatat
    89701 acagcacttt ttataacata tattaaatcc aaaatatctt tagcacttgc ttctccttga
    89761 ttgactacaa atccacaatg cttctcagat acttgtgctc ctcttaaagt aagacctctc
    89821 aatccagttt cttctattaa tttacctgca aaatatcctg ttggtctctt aaatgtactt
    89881 cctgcactag caaaatttaa tggctgttta gttattcttc tcgtcgctaa atcatccatt
    89941 aaacttttta tttcatcata atttccttct tgtaattcta attctgctga taaagctata
    90001 tatccgtttt tcgatattat actttttcta tacccaaatt ccatctgttc atttgataat
    90061 tcaaatatat tgccttccat atccatcagt cttactgact tcactatgtc cttcatttca
    90121 ccaccatatg ctccagcatt catggctaat gctcctccca atgtgccagg tattcctgat
    90181 gcaaactcaa acccttttaa ttcttgcttt tggagagctt tccctaaaac tgataataaa
    90241 gctcctgact gagcagtcat cctagtatca tttatctcat aagaattgaa attatcagct
    90301 aattctatta ccactcctct tattccacca tctttaatta aaatgtttga accatttcca
    90361 attattaaat atggaataga ttcttttttt accaacctaa gtacattttt taattgttct
    90421 tcagttctag gtctaactaa tatatctgct ggtcctccta ccctaaatga aatatgtttt
    90481 ttcataggtt catcgacttt tatatcctct ttacttaata tatttaataa atttatatat
    90541 atatcttgat tattcattgt atttcctccc aaattatact gaactttagc tgtcattatt
    90601 atttaaatta tattagtata tagtattaac tatattcaat aatatatgat tttgcttatc
    90661 atatggattt tatattttaa gcttcttaat tacaaactat attcaataaa tatataataa
    90721 agtaaaaaaa aaaaaataac aacatataaa agaatataaa taatttaaaa aaagcatcaa
    90781 tatcactgat atcaatgctt taaaaagcaa tttaattcgt attatttatc taactatttt
    90841 tgacatagca aagataataa atccctccaa ctactatgga acctccaacg atatttccaa
    90901 gcgttacaaa taccaaatta gttataaatt gaaccatagt tatatttgct cctaatgcca
    90961 ttcccattgg tataaaaaac atgtttgcaa cactatgttg gaatccacat aatacaaata
    91021 gcattattac tgtccaacat gaagccaatt ttgacattat atcttgagat gctgtagaca
    91081 tccatacagc taaaacgact agaatattac aaagtattgc ttttaaaaac attgatgcta
    91141 tagttgaatt aaccttagct tctgccacag ctatagcttt tgtagctgca tctcctgtca
    91201 atgtagaaga ataaaacaca agtgcaacta gcaaaattga acctactaaa tttgcaaaat
    91261 aaaccagtcc ccagtttctt aacatttttc ctaatgttat ttttttgtcc ataagtgcaa
    91321 tagccattaa ggtgtttcca gtgaataatt ctgctcctgc cactactaca agcataagac
    91381 ctactggaaa gaccatagca cttaaaaagc tagctacccc tgggtctatc ttgccaaaag
    91441 tttgactaac tatcatactc cccaatgccc caaaacctat aaatgctcct ccaaataaac
    91501 ctaatagaat tgcattttgt gtcgaaatgt ttgctttttt aatgcctgca cttatagttg
    91561 cttgtgcagt ttccccaggt gtcaagaatc ctttactcat aaatccttcc cccttaaaaa
    91621 ttatactttc ccttgtcttt ttatggcaat aattatataa taacaatatg atatataata
    91681 aa
//
LOCUS       DACTZW010000005        77814 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.005, whole genome shotgun sequence.
ACCESSION   DACTZW010000005 DACTZW010000000
VERSION     DACTZW010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 77814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 77814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..77814
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.005"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            403..1677
                     /locus_tag="JAM15_01935"
     CDS             403..1677
                     /locus_tag="JAM15_01935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HAT6797035.1"
                     /translation="MQFMDVSKYIEGANLKVKTKNGETVKRIYFNNSATPLVLKNVVD
                     NLNCEIPWLTYINAPGIISEKNTLKYENVRSTILKLIDGDEEKDSVIYVKNATEGINS
                     LAKFFKDENPDKFVITTAMEHMANYLPFKVNFPTKVVGITEKGELDFCQLENILKNYA
                     GNVSLVTVTGASNVTGITTPIYEIARIAHKYGAKILVDIVQVIQHKPFSMMPHECDEH
                     IDFVVFSAHKCYSPLNGGALVGPKKFFEKFNPVLYGSGSTKFVNDNKILYANVPQRFE
                     AGYPEYFGTLAMGKALNTLNKIGLNRISKYERELFLYAKEEMSKIPNIIIYGDKSNNV
                     IIPNISFNISNMYYKDVAKYLVDNFGIETGAGVVGADIYVQKLLGISPKEAYVRFIRE
                     NPVGLVRISLGMYNTFDEVDSFIHAIKTLAFK"
     gene            complement(1884..2201)
                     /gene="trxA"
                     /locus_tag="JAM15_01940"
     CDS             complement(1884..2201)
                     /gene="trxA"
                     /locus_tag="JAM15_01940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HAT6797036.1"
                     /translation="MVKIINNNEFINEVENKDGLVVVDFFATWCGPCKMLSPIYEALG
                     NEMVEKANFLKVDIDQSIELAQKFEVSTVPTMLIFKDGKPVDRLIGFMPKENLKNKIE
                     SYM"
     gene            2468..3214
                     /locus_tag="JAM15_01945"
     CDS             2468..3214
                     /locus_tag="JAM15_01945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HAT6797037.1"
                     /translation="MDNIINELQNIGFTKYESQIYISLLKESPLTGYEISKLSGVPQS
                     KVYENITKLLNNNIIINVGTDPIKYIPINPNELLKNKKKEFDNSMDNLKNSLQILNKN
                     KSVEYVLNIKGDKNILKKALEMIKNAKQEIIISCPYEEILELKKELLIAYKKNINIEI
                     LLLENKSLEGLDNIHIHGGNKTTLENKMLYKGIILIVDNDEILTGNLSEGSEAISIWT
                     KNSNILYIGVQYIKHEIYISEQIKGGYKNE"
     gene            3207..4088
                     /locus_tag="JAM15_01950"
     CDS             3207..4088
                     /locus_tag="JAM15_01950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HAT6797038.1"
                     /translation="MNKIKIKQVDAFTTIPFGGNPAGVVTDASNISDEIKQNVAKEMN
                     LSETAFVSESNVADFKVQFFTPGLEVDLCGHATIGTFHALLEEGKLNTNKSIFYQETK
                     AGVLSVELKEINNENIFMMEQNTPEFENLDNYRKELAQMIGVHEDRLLEYPIIKVNTG
                     LWWLVFGLKSLNDLKNISPDLNKIKKFSGDNNIIGITPFCIETIDKKCDYHLRSIAPY
                     VGVTEDPVCGTGNACVSSYIVHHNILDKTNFIGEQGNFINRPGKVYVNITKENNDITS
                     VKIGGSAYTILSGEIMY"
     gene            complement(4314..5669)
                     /locus_tag="JAM15_01955"
     CDS             complement(4314..5669)
                     /locus_tag="JAM15_01955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HAT6797039.1"
                     /translation="MSSTVKKKGKFPMGFYICSTTFSFERAAYYASKYLIYIFLTTAI
                     VHGGLGIDKGQAAIMQANLVAFTYLAPIIGGYISDRWIGARYTIPIGMLIMGVGYYLG
                     SIATTVSMVNAMIILVSIGTAFFKGNVSAVNGQLFDSQEELDTAFSVQYSFVNIGSFI
                     GTIAVGILYLKTFAKNGVLGFSQCFFIAAVLCVIGAIWFIYGWRFLGNAGKRPFKEGV
                     VAEKVEEKDKSPLTSMDKKRIWAIILISFFSVIFWVFWYLTYLAVYDYGAAFVNMNVG
                     GFDVPLAWFDSLNSLVCIVLGPVLGALWFKLASRPQGDMSLFKKTGLGLIFLGLAFLM
                     LVGAEFSRGVGAPETAKASILWIIMFGILLSLGEMLFSPLGNSFVSKYAPKKLLGVLM
                     GVWTFATFIAGKGYGYIYAFTLKFDMIKVYTIIPVILFVAAILLFLSDKTLSRLVEDD
                     K"
     gene            complement(7585..8082)
                     /locus_tag="JAM15_01960"
     CDS             complement(7585..8082)
                     /locus_tag="JAM15_01960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HAT6797040.1"
                     /translation="MFKIDDYIMYGMTGVCKVMDITNERFTNGIKKEYYVLSPIYSNN
                     TVIKIPVDNEKVPMRKLLSKINVLSLINDIPNMDTSWIDNEKLRSEQFKKILRGGKCE
                     ELIKLVRSIDNNREYVKSIGKKTHQADDNIMKEAERLLNEEFATILDISPNEVSSYIS
                     SHIPQ"
     gene            complement(8305..9714)
                     /locus_tag="JAM15_01965"
     CDS             complement(8305..9714)
                     /locus_tag="JAM15_01965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797041.1"
                     /translation="MENYFDKQAKELYNKASEIINTHSMLKANRANEKFDMDIPQDFK
                     YEFFSLVDKVNLSLMEEEDNFYGYFLFQMSREIRFDISSPTGVNFKGAKYVIYFNPII
                     FLTLDIKQMETTIKHEIHHILSMHLMRAKELKGKYSTLAINMAMDIVVNKFLNNLPPY
                     ATTLEWVNLKYSLKLEPYEPFEYYVEKIQTELDLMEVDEDGEEDDSDKYGDVEIDYSP
                     ERTHDIWDESNEIDENTLREFTEKFINSSQKGKVPAYLESMISSLKNSKGELPWNLYL
                     NRIMGTVENNKKKTITRRNRRQPNRLDLRGELRSHKAEIAVALDVSGSISDEEFKQAI
                     KEVLSIVKNYNHEITIIECDNEIRRVYKVRTEKDIKDRIRIGGGTRFSPVFEYANNKK
                     INLLVYFTDGKGENKLQVIPRGYKILWVISGRGDKISLKEPYGAVKKLTKVKTNDEIL
                     EINDVRNDGYSMNSQAPIL"
     gene            complement(9718..10848)
                     /locus_tag="JAM15_01970"
     CDS             complement(9718..10848)
                     /locus_tag="JAM15_01970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010074319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAT6797042.1"
                     /translation="MNFIDTLKSVDLILSTGEVPLIVGESGIGKTALANKLAKENDWS
                     LIVIDGNLLKEGEIGGLPTIESYVGVNSNGYKTEKKTTVYAVHNKLREIDEEISRSKT
                     VLLFIDEINRCEHTVQQELMNLILNREINGYKLHDDVKILAAMNPSSKYGSDFDYQVV
                     DMDAAQENRFVWLNMESDHTQWIKWAIDEGIERKVIEFISTFPEYLHKINEDDVRATP
                     RSYERVSKIYKVYKEKNNSIPRAVFLNVVKGNVGKVIAEEFISFIESNSEPLISYEDV
                     FLGESIDESIVERVKNESHTRLYLSAMNILKDLELNIKNDKYESNHYINRFIEFLKMY
                     PVDLMIGIMKDIRNSYIEVYKKAIENEDFVKSYFESYSLIRG"
     gene            complement(10860..11663)
                     /locus_tag="JAM15_01975"
     CDS             complement(10860..11663)
                     /locus_tag="JAM15_01975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010074318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797043.1"
                     /translation="MEKLRVIEMIKNNPNIIATIDNPTDEMKLLAIKENGLVLEYINN
                     PTREMQELAIDNNIRAIKFIDNPTEDMMIKAVNEGWSILDYIKNPTDKVIEMAINQAG
                     WAIKYARNPSEELQLLAVRKNYDSIKFIKQPYESVQEEAVRISYDALRYIDSPSYNAE
                     LIAIKNNEAAISFITDLDKNKMLEFLKVNILVIKYILKKVSKDELESVLKEVLSKEDV
                     EEKYIRDFLNCSVIDRNSESIPIDKIMFIYKYGSKTAKKIAVDEKLKIM"
     gene            complement(12047..12928)
                     /locus_tag="JAM15_01980"
     CDS             complement(12047..12928)
                     /locus_tag="JAM15_01980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline iminopeptidase-family hydrolase"
                     /protein_id="HAT6797044.1"
                     /translation="MKITEGYMPFKGFKTYYRIVGENTEGKKPLVLLHGGPGSTHNYF
                     EVLDKIAESGRQVIMYDQIGCGNSFVEGHPELFNADTWIEELIELRKHLGLDEIHLLG
                     QSWGGMQAIWYAIEYKPKGIKSYILSSTLSSAKLWEKEQKRRISYMSEVDQKALLDAV
                     NTGDYSSKEYNDALERFMEMYCAGEVTEDSPECLRRPKKSGSEAYIVGWGQNEFSPTG
                     TLSGYEFTDRLHEIKEPCLVTSGAIDLCSPYIAKTMYDRIPNSKWELFEYSRHMPFVE
                     ENEKYIKVLTEWLDAND"
     gene            13385..14359
                     /locus_tag="JAM15_01985"
     CDS             13385..14359
                     /locus_tag="JAM15_01985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797045.1"
                     /translation="MNNINSLKVIKLSLGCSLAIFIAWLLKLEYSMVAGVIVLLTVKD
                     TKRETLKGSIGKIYGFLLCTIFSYLCFNILGYNLTSFSIFIFIIIPLCFLLNIQDVVA
                     MCVVIASHYYLQGETSIKWILNEAGIFAVGTGIGVLINMYIPTNIHKIYEVQKKLQEE
                     VSIVLIDIADIIVNPKKENGYSRDLYTLNSLIDSSISETYDNINNTLLSDTRFFLEHM
                     DIIKSQRDILENLYSYVSQLNSTPPQAHILSAFIHKIGYTEFEAETGNLLLEELKRLM
                     LSMKNQPLPVDRTEFENRAILFLCLTELKQFLVNRKHAQMLRDNNFYK"
     gene            complement(14475..15506)
                     /locus_tag="JAM15_01990"
     CDS             complement(14475..15506)
                     /locus_tag="JAM15_01990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HAT6797046.1"
                     /translation="MKKIRKLATKLLITTMVLISGMSMTVYGITAKEVTAKTPKSYVT
                     GTNSVYGPKLSQAQLNSVAQATADFMNNKITKNMTTDAKILVAYNHIKNNTTYVDWNA
                     VEGANTAYTLVTKKGACSGMARSMKALCDAMGIESYYVHSTSNDHQWNLIRFGDGRLY
                     HVDIDANKSAGKDIIYKSLRHPLPFDKTAYPTVGAVAQTQKPAPPGKHTMLPHQDGAK
                     VVGKFGDIKDKHVMYEGVRCVVINSSVNTVTFLGSKSNLDPSNLTIAVIGFMNTPYGM
                     FALAPEGEPVEYPFKYDKPFSLDFSGKNRSGAELAKYCKKNDVTIKIEITDEKANIGL
                     GQIMYIRYE"
     gene            complement(16117..16968)
                     /locus_tag="JAM15_01995"
     CDS             complement(16117..16968)
                     /locus_tag="JAM15_01995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAT6797047.1"
                     /translation="MSCILKLKQIYEDLTEVDKKIADYILNNTEAISKLSVSELASNS
                     KTSTASIVRFSRKMGYSGFGDLKIEIAKDLMGKENEYTYVDENYDCNIDSVINKITNK
                     NIETINQTRLLNEKDIIKEAVEQIIKAKNVYIFGVGGSALVALDLQMKLLRINKQAFT
                     SLDSHTQLMVSSNVDKEDIAIAISYSGESKEVIKSIENAKLKGCKVICITKYSDNHLS
                     KISDLKLVVPNIEKRLREGAISSRIAMLTLIDIIYISIIQENLNEAEQKLQETKRILD
                     YLNINNA"
     gene            complement(16985..17905)
                     /locus_tag="JAM15_02000"
     CDS             complement(16985..17905)
                     /locus_tag="JAM15_02000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA reductase"
                     /protein_id="HAT6797048.1"
                     /translation="MYFLGVDGGGTKTTFTLVDEELNIVGTITKGTCHYNQIGFDNLT
                     KLLITGLEEVCKDAKINVEEITYAFVGLAGYGKIKEVLYALEVATKNAYSHINYTLGN
                     DVEIALAGSLNGEKGINIIAGTGSIAQALDKDGNLHRCGGWGYVLGDEGSAYYIGMAT
                     LKMFTMQSDGRCSKTKLYDLIKRHLNIENDYDIIKYVNDGIQGDRIEIAKFATICLKA
                     VIEGDNTASKIFDDAAYELSRLIIGLEHHFEQGTKIKVSYSGGVFKSGDLILEPLKKY
                     LNKTRFGIVRPVLTPDLGACLLAKKKYYSK"
     gene            complement(18015..18929)
                     /gene="murQ"
                     /locus_tag="JAM15_02005"
     CDS             complement(18015..18929)
                     /gene="murQ"
                     /locus_tag="JAM15_02005"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HAT6797049.1"
                     /translation="MLIKTLENLVTEGRNKNTLQIDKEDTLGIIELINNEDKTVAYAV
                     EEQKESIAKAVNIIVDRMKQGGRLFYIGAGTSGRIGILDATECPPTYGVDFELVQAII
                     AGGNQAIFKAIEGAEDDKELGKQDIIDRGVTSKDVICGIAASGRTPYVIGAMEYAKEL
                     GCAVLSITMNPNSEMSKKADLPINIIVGAEVIMGSTRMKSGTAQKMVCNMLTTASMVK
                     MGKVYSNLMVDVKTSNEKLVERAKRIIMIATNVKYDVAEKFLEEADNSVKLAIFMIKS
                     GLDKDSAKSILDRQEGYISEALKSIEKL"
     gene            complement(19028..20124)
                     /locus_tag="JAM15_02010"
                     /pseudo
     CDS             complement(19028..20124)
                     /locus_tag="JAM15_02010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898112.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
     gene            complement(20357..21703)
                     /locus_tag="JAM15_02015"
     CDS             complement(20357..21703)
                     /locus_tag="JAM15_02015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAT6797050.1"
                     /translation="MLDKFTEFLDSKLSTSMARLAEQRHLRAVRDGIVASLPLIIVGS
                     FFLILAFPPLPDSWGVTQYLKENAVTILLPYRMTFFIISVYSTFGIGYSLAKSYKLDG
                     LTGGLLATATFLLTIVPTAIEGLTPDLLKIVEKSPELLAWYNSIPQGWQMPMANLGGG
                     SMFVAIVTSIIGVEIYRFTDKSKFKITMPEAVPASVTRSFEALTPAALIIILMAIVTY
                     FLGFDWHGFIAKLVTPLVSATDTLPSVIILIFLITFFWSFGIHGVSIIGSLARPLWIQ
                     LLDANTASYAAGQAVPGIAAEPFFQWFIWIGGSGATIGLALLLAFRAKSAYGKSLGKA
                     TVIPAIFNINEPIIFGAPIVLNPILIIPFVVAPIVMATVSWFAMSANLVSRVVVTAPW
                     TLPGPVGAYLATGGDWRASVLNLLCIAISIIIYYPFVKMYDKRLLHEEKVEEQEAY"
     gene            complement(21792..22100)
                     /locus_tag="JAM15_02020"
     CDS             complement(21792..22100)
                     /locus_tag="JAM15_02020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAT6797051.1"
                     /translation="MRVLFVCSSGMSSAIAVNALQKEGAKNGIDIDVLAVGTQEFENE
                     VKNGWDIAMVAPQVRHRFDYLKAFADEASVPCALIQAQAYSPLGGPKLLKQVQELLSK
                     "
     gene            complement(22361..22759)
                     /locus_tag="JAM15_02025"
     CDS             complement(22361..22759)
                     /locus_tag="JAM15_02025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797052.1"
                     /translation="MSNNKKKKRKKNNNYKNAKSTESNKNTKKEMEKNQRTDYNIPTI
                     SFKSGLILIVSSLVSTVVFPLLLSIFGIDNRFGVVIGNSLITSFAVAYTRYFVETKRG
                     FSLGFFRLYILFVLSFAIIGYFWIYKGIHI"
     gene            complement(22761..23921)
                     /locus_tag="JAM15_02030"
     CDS             complement(22761..23921)
                     /locus_tag="JAM15_02030"
                     /EC_number="2.7.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anhydro-N-acetylmuramic acid kinase"
                     /protein_id="HAT6797053.1"
                     /translation="MITMYSVGLMSGTSLDGVDAVLAEISGNGRNTKVKQIEFITLEI
                     PKDIKDEIRKCCIEEESSVDLICSLNFKLGYLFSKAVKSVCHKANFHIANLDFIASHG
                     QTIFHIPRSYNNFVSSTLQIGEPAVIAYETNTKVISNFRVMDIAAGGEGAPLVPYSEF
                     LLYSDKNKNLALQNIGGIGNITIIPKSCNIDDVFAFDTGPGNMIIDGVSQRLFNRKYD
                     KNGYFASKGKINEEMLKDLMSHKYLSQAPPKSTGREVFGQVYLDNMLNKYKHVDKYDL
                     IATVTMFTAKAIYYNYKNFILPKVNVDTLLIGGGGAHNLTLIGYIKELLLEVEVLTQD
                     EYGYSSDAKEALAFVILGNETLNNSFSNVISATGAKNKVILGNITPKPFGGK"
     gene            complement(24352..25371)
                     /locus_tag="JAM15_02035"
     CDS             complement(24352..25371)
                     /locus_tag="JAM15_02035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAT6797054.1"
                     /translation="MLVKYLKGRSKYIALPLVVVSIINIYLFAIDILKNRYSELIYLD
                     FLVLFIIMVFFVIDYKNFRNSYINLYNCIENSGEIDSYLIDGQSFEENLIKDIIENLK
                     IKNNSDIETYKQSLKELDEYIAKWVHEIKIPISSLSIITDRLSSIEDSLDIKNQVAKI
                     NFLVNSILYSSRSNTMFEDVFINKFNLEKLVKMSIKNNSFLLIKNNVEVSLNELENDV
                     YTDSKCMSYVLDQIINNAIKYSKEVGKIEFNSKKLENGVVLSIKDFGIGINEEDISRV
                     FDKGFTGKNGRNQLYKSTGMGMYFVKKMIDSLGHEIEVCSKIGSYTIFNIYFYDISDY
                     LSLDS"
     gene            complement(25371..26045)
                     /locus_tag="JAM15_02040"
     CDS             complement(25371..26045)
                     /locus_tag="JAM15_02040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6797055.1"
                     /translation="MYRILLVEDDIDLSKEIALALEKWGFKVELIDDFEVVLDEFMDK
                     KPDVVLLDVNLPLYNGFYWCEKIRAISNVPLIFLSSRDSDMDLIMGINNGADDYITKP
                     FSIDILVTKINGIIRRVYNYSDSNSILYCEDLMFDVGKGIIKHKYKDKSIELTKNEIK
                     ILTLLLKNKNRVVSRESLMMTLWDNDEFVTDNALTVNMNRLRSKVKELGFDDFIKTKK
                     GIGYII"
     gene            complement(26197..28104)
                     /locus_tag="JAM15_02045"
     CDS             complement(26197..28104)
                     /locus_tag="JAM15_02045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAT6797056.1"
                     /translation="MSILGIAYNNFKSNIRTYLAFFISMVFSVVVLTNFELLRYGDAI
                     NVLQEENKKFTLSVLVAVIMILSVFLFFFIWYATNIFFKNRSKEIGILSFMGLDLYTI
                     GKIYFVENMLIGISSCITGIIIGIITSRFFQVVIIKLSGFNIKVSNGLSIEAILYATL
                     IFISIFIIMAVKGFITICRSSVINLINISKKQEKIPKVGIGIYILAIVSIIVIGYGYY
                     LSTNIRTGDITSVLPVIGIIIVGTYGLFKSVMPVIFDIIIKNKKILFNGNNIIAINNI
                     NYRLNKNYKTYAIIAIIITTTISTLGASVAMKHIHKNAQEQRNVYAISIVSMDKDEVN
                     KKQIENIIKDTNKIKYSVNPELTILKKTDIKEAYDTTDTIMKYSDFCNTLKVNGNDKE
                     LKEYGERLVSGNNVIELKSPQTIASIATKEAKTKLDGQLYNISRGEVKVPVLGTGLNQ
                     SIIVVNDDTYFKLRDKGQQVYFYGAKVFQEENSQVMFNNIEKNLSLKNGYIQNGYKAQ
                     GESQWMKFAYVVLVFLFLVFAIVAGSIIYMKIYSDAYEDKEKYKILLKIGTTEKDINR
                     AILKEVAIFYTLPMLSATISSYFALRLAGDLLMSDLSGIYILSLVICLIIFVIYGAVS
                     VNKFKSVVYKN"
     gene            complement(28105..28857)
                     /locus_tag="JAM15_02050"
     CDS             complement(28105..28857)
                     /locus_tag="JAM15_02050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6797057.1"
                     /translation="MKEILKIKNISKDYGIKGFKTNVLKNISLTVNEGDFIAIMGPSG
                     AGKTTLLNLMSTLDKQTSGEIILDGINISKVKNNELSKLRREKIGFIFQDYNLLDNMK
                     LMDNIALPLALGKKKSKEIEAKVFSIAKKFGLENHLDKYPYQLSGGQKQRGAAARSLI
                     TNPAVIFADEPTGALDSKSAYELLESLEKINRENNATIIMITHDPLTASYSNEVYMIN
                     DGNIKCKLNKGNSRKEFYGKIMDMLASMGGEM"
     gene            complement(29175..30329)
                     /locus_tag="JAM15_02055"
     CDS             complement(29175..30329)
                     /locus_tag="JAM15_02055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAT6797058.1"
                     /translation="MINKAIKFKFIIFYFFSYIIFAFASTKFTPFLSKLGYSAFERGI
                     ILSSYAITNILFQLLFGVLADKYQTMKKIVLISLSVYGIASVIMFSTESATFIIYLLL
                     VALSGGLLNTCCSLYDTWIIGCGDNINNYLSFIKTFGSIGWAIGSMVASYLILRFSYF
                     GLSVAIGLIVVLLIINILLLPDIEKINKKINVTNKDIIELLKDKKYILLVCILFLLYS
                     MVVANNCTVIDKMIALNATNSQISLKWSLQSLLEIPTYLAGSYLLKKYSSLNLLKLSA
                     IMITVQFLLFALTNDSNIIIILCVFQVFSTPLILITSKRLIFEVSPKKLRSSSQLIAL
                     SIFMGGSSLIIPTVAGFLSINIGYNYTLMILSLFGCLAYGLIVLLNYLQE"
     gene            complement(30332..30799)
                     /locus_tag="JAM15_02060"
     CDS             complement(30332..30799)
                     /locus_tag="JAM15_02060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAT6797059.1"
                     /translation="MFFKRKKEASTINSYIDGKIINLGEIPDKVFSTKVMGDGFAMIA
                     KDNILKSPTKGVISFIAQTNHAIGIKLQNDVQILIHIGLDSATTKKENFKLEVKQGQE
                     VNMGEKLVEIDNKLLENTLYIPLVIVENPNTVKYHLSNLNQEGNSGIKVINFD"
     gene            complement(30813..31301)
                     /locus_tag="JAM15_02065"
     CDS             complement(30813..31301)
                     /locus_tag="JAM15_02065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797060.1"
                     /translation="MITNKIKNITAVLKDENIFLSVVMVCFLILPVLYIVYLELTSLF
                     TNISFSQLLNNDVNASLNLISNFSAVYSAYVIYNIKKNKEIKENMIAFYLVLLGQIFQ
                     IYTITIVIMFTYIYKFVGIKQIISSIKELQWGKSYKALFSSIAVCLISLFVMIIRIKL
                     IM"
     gene            complement(31315..32646)
                     /locus_tag="JAM15_02070"
     CDS             complement(31315..32646)
                     /locus_tag="JAM15_02070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HAT6797061.1"
                     /translation="MERKRQRILIAGGGSTYTAGIVTMLIESVAKFPIESIKLYDNND
                     ERQRKVAEACAIIVREKNPEIKFSYTTNPEEAFTDIDFVMAQIRVGLYALREQDEKIP
                     LKYGVVGQETCGAGGIAYGLRTIGPIIEMIDYMEKYSPNAWMLNYSNPAAIVAEACRV
                     LRPNSRIINICDMPVCLEEIFARILGLNSRKDFDVRYYGLNHFGWWTSIKDKEGNDLM
                     PKLQEYCAKKGYEEFTPQGQHKESSWLETMRAAKDLLEIEPTTLPNTYLKYYLMADET
                     VEHANPNYTRANEIMDRREKDTFEECERIIKNGTARDTWFDASEHSQFIVELACALAF
                     NTQERFLLIVPNNGAIENFADDAMIEIPCLVGKDMVEPMSIGKIPTFQKGLMEQQVAS
                     EKLAVEAWIEKSYQKLWQSFTMSKTVPSAKVAKEILDEMIVANKDFWPTFK"
     gene            complement(32660..34225)
                     /locus_tag="JAM15_02075"
     CDS             complement(32660..34225)
                     /locus_tag="JAM15_02075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAT6797062.1"
                     /translation="MMKKIQRFGGAMFTPTLLFAFAGIMVGFSIVFQNQSIMGSLATP
                     ENIWYQFWGVISSGAWMVFNQLPLLFAISLPIALAKKQQARACMEALATYLTFNYFVG
                     SMLSFWGKSFGVDFAAEISAGSGLVSIAGIKTLDTGMVGALLISGIVIYIHNRFYDKE
                     LPDFIGLFRGSSLVVAICFFVMIPVALLTCFIWPHIQNVIRHLQTFFINSGNIGVWCY
                     AFLQKILIPTGLHHFVYAPICYDSVVVPGGTSVYWATHIQDFQTSAKTLKEMYPIGFS
                     LSGLSKVFGSLGVFGAFYVTAKPEKKKKVLGLMIPATLTAVLTGITEPLEFTFLFVAP
                     LLFLVHAFLDACLQTISFALGVVGDFGGGIINWVVLNWLPLGMYHWKVYVVQVVVGII
                     FSFIWFFVFTFLIKKFDMKTPGREEDSEETKLYTKNEYLETKDEKGNKLSKASQQASE
                     YIKLVGGAENVVDVTNCATRLRLTLKDDSIISKEEDFKVVGAHGLVHNGKAIQIIIGL
                     SVPSVREEFENLL"
     gene            complement(34394..35179)
                     /locus_tag="JAM15_02080"
     CDS             complement(34394..35179)
                     /locus_tag="JAM15_02080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAT6797063.1"
                     /translation="MRLEEMIFLNYNKLNDTDLLIWKYITANKKHCSKMSINELAMKC
                     NVSRATITRFVKKLDLKGFSEFKVLLSWESEKVHVIENQSFDIACNSIIKYVEDQKNK
                     DYDALCKLLYESRTIYAYGSGDIQNVVAKQIKRMFLSCQEIIYDFEGRTFDDSFYNIV
                     SKNDVMIIISLSGENENTLNIARRLKLIGTKIISITEFKNNTLTDLSDESIYISATNI
                     SFLQMHPSYKLTMLYFILIELLFIKYSIYKRHRMITEGIDCKL"
     gene            complement(35346..36545)
                     /locus_tag="JAM15_02085"
     CDS             complement(35346..36545)
                     /locus_tag="JAM15_02085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S41"
                     /protein_id="HAT6797064.1"
                     /translation="MKKKVLFLVIILAFIILLGNSTYSQKNQLSEEEKVDDFNYVYNV
                     VKTGYPYLGVNKRLNNIDWLANKDEYTKRIKNTENDEEFIEELSSILSDLNNKHTEVI
                     DNKKRYELFKKSYSNNDWYDFLNDKKVVDRYDSMNLKIKMPDDIFVKKELILKDVIKG
                     QIGYMYLPSMSSKNGSINNDLKIIGDYINTLEKHKALIIDIRGNLGGSDRYWQGIVSK
                     LIKNDVKINGYRIYRNNNEIVKKYTNARNIKLNPVENLPASVKENAPKEIIKDFNDFE
                     DTSYTIKSTDDSKFKGNIYLLVDRKIYSSSESFAMFCKETKFATLVGETTGGDGGCID
                     PVLFNLKNSGLIVRMASCMYLNKNGICDEEFKTIPEFKVKDCKRTADFKDDNCIRKAL
                     ELENINY"
     gene            complement(37067..38404)
                     /gene="xylA"
                     /locus_tag="JAM15_02090"
     CDS             complement(37067..38404)
                     /gene="xylA"
                     /locus_tag="JAM15_02090"
                     /EC_number="5.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase"
                     /protein_id="HAT6797065.1"
                     /translation="MSEIFKGIGQIKFEGVKSDNELAFRYYNPEQVVGNKTMKEHLRF
                     AMSYWHTLCGEGNDPFGVGTVERPWNNITDPIEIAKIKVDAGFEFMSKMGIEYFCFHD
                     RDIAPEGRDLEETNKILDEIVEYIKVNMEKTGIKLLWGTANMFGNPRFVHGASTTCNA
                     DVYAYAAAQVKKAMEITKYLGGENFVFWGGREGYETLLNTNTELEMDNFARFLQMAVD
                     YAKEIGFTGQFLIEPKPKEPTKHQYDFDTATVLGFLRKYNLDKYFKMNIEANHATLAG
                     HTFQHELNIARINNVLGSIDANQGDLLLGWDTDQFPTNIYDATLAMYEVLKQGGIAPG
                     GFNFDSKVRRASFEVEDLFLAYIAGMDTFAKGLLIAHKLLEDEVFENFTKERYASFSE
                     GIGKDIVEGKVGFKELESYALQMPVIKNKSGRQEMLEAILNRYIYEVDTISNK"
     gene            complement(38504..40045)
                     /gene="xylB"
                     /locus_tag="JAM15_02095"
     CDS             complement(38504..40045)
                     /gene="xylB"
                     /locus_tag="JAM15_02095"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HAT6797066.1"
                     /translation="MEYVLGVDIGTSGTKTVLFDKLGNTIKSCTYEYPLIQERSGWAE
                     QDANDWWKAVVESIREVVQSSNINSECIKGIGLSGQMHGLVMLDNEGKTLRNSIIWCD
                     QRTVKECEEITDLIGEERLIEITANPALTGFTASKILWVRNNEPDIYKNTNKILLPKD
                     YIRYKLTGEYATEVSDASGMQLLDIRKRDWSDEVLEKLNIDKNLLGKVYESQEITGYV
                     TRDVASLTGLKEGTIVVGGAGDQAAGAIGNGIVKDGVVSSTIGTSGVVFAYTKEPKID
                     KEGRVHTFCHAIPNTWHVMGVTQGAGLSLKWFKDNFCQSEVEVSNSLGEDVYEIINNQ
                     VSQVPTGCNGLLYLPYMMGERTPHLDPYARGVFFGLSPIHSKKEIARSIMEGVSYSLK
                     DCMDIIENLDIDVNEVRASGGGGKSKVWRQMQADMFNQDVYTINSSEGPALGVAILAL
                     VGAGIYENIQKACDAIIKTSTKLEPISENVDTYKIYHRLYKRIYKSLKDDFRLLDEVV
                     NSKNK"
     gene            40259..41419
                     /locus_tag="JAM15_02100"
     CDS             40259..41419
                     /locus_tag="JAM15_02100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HAT6797067.1"
                     /translation="MVTDKYTIREMNERLVLEQIIKNGPISRASIASTIGLNKATISA
                     ITKKLIDESLVHEIGIGNSTHSGGRKPILLVFNKCAGISLSMDIGYDYIFSSLSYLDG
                     TIINSKKLTDIQVSKDNVIQLIDEIINSYNISKIDTPYKVIGLTLAIHGITCENKVLF
                     TPYYNLNEIDLYSILSKKYDFPIHIENEANLTALAENTFSTVHNSLLSLSIHSGFGSG
                     IIINNKLYSGRNGMSGEIGHTIIMPNGKLCPCGNRGCLEQYCSEKKVFEQLSSLENIP
                     KIDSDIVKQLYYEDNQNAKKVIHEFCSYLTIAINNAITTYAPEIIYLNSQIISDIPEI
                     LQITKDMLVSSFNKGINIEISSLGSEASLYGGSAVNIKSFLNIQNLTLINEI"
     gene            complement(41575..41979)
                     /locus_tag="JAM15_02105"
     CDS             complement(41575..41979)
                     /locus_tag="JAM15_02105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAT6797068.1"
                     /translation="MNSIILMSHGNMAEEVLNSAKMIIGDSIDYPTVNMKQDDGIEGT
                     IEKLKKALEVYKESSEIIIMADLLGGTPCNAALLVANNDSRIKIISGLNLGMVIESAF
                     LDTKELAAKLEKIGKDNISMVEQNASLLSDDE"
     gene            complement(42000..42482)
                     /locus_tag="JAM15_02110"
     CDS             complement(42000..42482)
                     /locus_tag="JAM15_02110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAT6797069.1"
                     /translation="MEMKGIKNIRIDDRLIHGQVATMWSNKLGVTRLMVVNDAVANNS
                     VQKQVLRMATPAGIASSIITEETAIKNITAGKYEGQNVLLIVKSPVDLIPFVEAGFKI
                     HNINVGNMSSRKDTTVLRPNISVTEEEKEAFKRLLDEGIEITTIMTPDDKKTYLVDIL
                     "
     gene            complement(42502..43311)
                     /locus_tag="JAM15_02115"
     CDS             complement(42502..43311)
                     /locus_tag="JAM15_02115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAT6797070.1"
                     /translation="MSDKVSLNKSNEKVKKSVLWRWFFTSSVSSNYEKMQALAYCYAV
                     LPFLKVVYKDNPEKLQSAVLNHLQFFNTNPWVAPYILGINVAMEELSSEETEEAVASI
                     KTGLMGPVAGLGDSLFVVIPWTIFGAIAANMAIDGSPFGILLWIVVSVALKLLSIPLF
                     NAGYTSGTKLISSIEKSLKILTESTSILGLMVVGALIPSVVKANVALNFQQGDFTMKG
                     QEILDQIMPGLVPAILVVIVYWALKKNIKPIYLILGVMVVSIILYALGILK"
     gene            complement(43304..44083)
                     /locus_tag="JAM15_02120"
     CDS             complement(43304..44083)
                     /locus_tag="JAM15_02120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002582559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAT6797071.1"
                     /translation="MEPQLWQLLLIVLYGFFINYEKNSTMFGTYQPVTAGFITGLILG
                     DINTGLYIGGTLQLLSLGISNFGGASIPDYQTASIVATFITITTKQEASVGISIGIPV
                     ALLMVQLDVLRNTIGIWLVHKAEDGAKKGNYKNITYMQMLGVLLTAATTGIPVALSVI
                     FGPSLINTILKYTPEWLTGGLTVAGGLLPAVGIGLLLRYLPAKEYFSYLVIGFVLAVY
                     MKVPLLGVALIGGAIALIIYKKNLENQEQQYTVVGGMDEDE"
     gene            complement(44083..46161)
                     /locus_tag="JAM15_02125"
     CDS             complement(44083..46161)
                     /locus_tag="JAM15_02125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HAT6797072.1"
                     /translation="MIKISEDYIEKRFDNELLRIEAWGKNSLRIRSFVDQNFVDENYA
                     LNEKPKLNKDDITINKNEDGSVIIKNGKIKAVLDHRDRITFYNDKNEILLKEYIRLRA
                     VKHDDGGEDVGTIEITKDFNSTLKLKSREYRPSYSGEFEVTTRFESEPSEKIFGMGQY
                     QHKFLDLKNTVLELAQRNSQISVPFYISSLDYGLLWNNPGIGKVSFAKNMTEWKMFST
                     NFIDYWITCGESPKELNKNYSQVTGTVPMMPENLLGLWQSKLRYRTSEEVLDVVKEYS
                     KRGIKLSSIAIDYFHWPKQGEYKFDLDYWKNPKELVKKLKEEYSVEPIVSVWPTVQSD
                     AENYNDYLENGYLVNVNRGVRMTMQIQGNTVFVDMTNKNAREYVWDRIDKNYKQLGID
                     YYWLDVAEPGYSVYDFDNYRYKKGNVLSCGNIYPIDYLKMIYDGLHNDIESVVTLVRG
                     AWAGAQKYGALVWSGDIDSSFEAFNNQVNTGLNMGLAGIPWWTTDIGGFHGGNPKDPE
                     FRELMVRWFQYATFSPILRMHGDRLPHSKPLSNKGGGSMVTGAPNEIWSYGEEVEVIL
                     TKFIKIRESLKTYLKKLMKEAHEDGTPVMRTLFYEFPEDDKTWEVDNTYMLGDEILVA
                     PIMNYKDRSRKVYLPKGHTWENIFSGVSYEGGKTYEVECPLEEIPIFLKQDSSYNFKE
                     LKNILGEVKS"
     gene            complement(46952..47473)
                     /locus_tag="JAM15_02130"
     CDS             complement(46952..47473)
                     /locus_tag="JAM15_02130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HAT6797073.1"
                     /translation="MKRNREIVVVCHCILNCNSKVEGLSEFKGAQNIAIDLVNKGYGI
                     IQLPCPEMIMYGINRWGHVKEQFDNLFFREQCRQMLIPHVRQFDEYLKNDYDIKSIIA
                     IDGSPSCGYNKTCSSKRWFGELSGCNELMDKINDIQMVDGKGIFIEELEKLLKEYNLE
                     IPIVGFDELREDK"
     gene            47640..48206
                     /locus_tag="JAM15_02135"
     CDS             47640..48206
                     /locus_tag="JAM15_02135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAT6797074.1"
                     /translation="MDTKKITFSSMCIVINIVLGMVISMINIPLLFLDTVGTVLGAVV
                     LGPFWGALIGGCTNLVLGVISGPTNIPFALVNIVLGLIVGYISKKKGFGYKEAIITGV
                     ILSIVCPLIGTPISVLLFGGLSGSGADLLVGFLVQSGQKIFTAAFFPRILSNIVDKPL
                     SCIMVVYFISKMPKGFIKQYSKNTSSSY"
     gene            complement(48423..50486)
                     /locus_tag="JAM15_02140"
     CDS             complement(48423..50486)
                     /locus_tag="JAM15_02140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF262 domain-containing protein"
                     /protein_id="HAT6797075.1"
                     /translation="MKAGEIEFLSYLEGSNKSFVVPVYQRNYNWKKEQCKRLFDDLED
                     IIDSGFRTHFLGSVVSIYSMGKEYLIIDGQQRVTTVSILLIAMCQIIKEFGESKGIIT
                     TEEQIKECYLINKHSRDKDGKIKLKPIAEDRKAYYELFEEEMNTDRNSNIVSNYLYFY
                     NRIKEDNISIDDLFDAIQKLTIVEIELKNGEDDPQLIFESLNSTGLDLSEADRVRNFV
                     LMGRSSKLQEEFYNNYWYKIEKNTSSNVSSFIRDYLTIKERSIPNKNKVYFSFKRYVS
                     DNGIDIEILLKDLLKFSNYYREISYSCTDDNDVNKVLKRINKLEIFVSYPFILELFND
                     YNEGIINKKVLVESLNLVECFILRRIVCDVPPNALNKVFMNLGREIKKFSDYKENYSN
                     ILRYIFINKKSSQRFPTDSEFSNAFETKDIYNTKSKNKLYILERLENYNNKEIVDLEN
                     LINNNMLNIEHIMPQTLTNKWKESLGDNYKEIHDKYLHTIGNLTLTGYNSKLSNKTFE
                     EKKEMEDGFKDSRIYLNKYISSIDKWNEEEIKNRTKILLDRAVEIWKYPSVTYEPPSN
                     SENIFTLEDDDVNFTNESIVSFSILGESYKAKNWTEFYEQVALTLYDLDSVRFNSIVD
                     KTYKRDFIDNIKSRDAYKLRKGIKISENIYLETNLNTEAKLNIIRFLLNEFDIELNEV
                     IFSIK"
     gene            complement(50867..54202)
                     /locus_tag="JAM15_02145"
     CDS             complement(50867..54202)
                     /locus_tag="JAM15_02145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAT6797076.1"
                     /translation="MGNFDFLQKKKNFNSFNTACLEAEKSILVSPSTCATITRRALEL
                     AVKWLYANDSDLVLPYQDNLSTLIHNNSFIELIDYDMLPLLKYIVKLGNLSVHTSANI
                     ERGEAILSLNNLHQFVSWIDYCYSDEYTAEDFNEDLLLHGEEKRTRPDELKNLYERLS
                     SKDKKLEEVIKENEELRKSLTEKRKVNTVNYDFKIDEVSEFETRKRYINIELKLAGWE
                     FGKDIGEEIEVQGMPNESGVGYVDYVLYGENGKPLAVVEAKRTSKDPKIGQQQAKLYA
                     DCLEKRYSQRPVIFLTNGFDMYIWDDYSDRKVYGFYKKSELQLMIDRRKSKKSLSSVT
                     INDEISNRYYQKEAIRAVCEALENKQRKTLLVCATGTGKTRIAISIVDVLSRHNWIRN
                     ILFLADRKALVKQAKKSFTKLLPNLALCNLLDSKDSPEDARMIFSTYPTMMNAIDDTK
                     SKDGKRLFTPGHFDLIIIDESHRSIYKKYKSIFDYFDSYLMGLTATPKDEIDKNTYSV
                     FDMENGVPTYAYEYNKAVEDGYLVDYTSIEFKTKIMEDGIKYDELSDEEKEEYENTFN
                     DDESIGDEIGNNAVNEWLFNSDTIDLVLNKLMTEGLKIEGEEKIGKTIIFAKNTKHAR
                     AIVERFNKLYPKYGGNFVKAVDYSINYVDSIIDDFSDKNKLPQIAVSVDMLDTGIDIP
                     EILNLVFFKKVRSKTKFWQMIGRGTRLCPDLLGVDMDKERFLIFDFCNNFEFFKFNPK
                     GFEGNKAETLTEKLFNIKVSMVKELQDIKYIEGKYAELRKELLEELITSVKALNEDSY
                     IVRMNLSYVHKYKNENVWSNIGAVAQNEIREYISPLITSYSDDELAKRFDVVMYNIQL
                     AYLQNNNASKGIRHVMVTAEKLSKLGTIPQIQQQKYTIEKAMTEDFWEDSDIFEVEEV
                     RISLRELIKYLEKSSQKIYYTSFEDMIVAEDRNDSVYNANNLKNYKKKVEYYLNSHKD
                     ELAIFKLRNNKKITKQDVETLEEILLKQLGNCDDYKKEFGDTPVSQLVRKLVGLDREA
                     ANEAFSEFLNNKSFNTKQIHFVKLIVDYVVKNGFIEDNKVLMEDPFRTVGSIIDLFEN
                     HIEERNKLIKTINKIKENASEIG"
     gene            complement(54252..54680)
                     /locus_tag="JAM15_02150"
     CDS             complement(54252..54680)
                     /locus_tag="JAM15_02150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797077.1"
                     /translation="MVIRNKLSWNSIEEVNRDFGSCLYDLQNFKILYDKEEMPELWAR
                     YIKEGFKSYMVSFLELTKAMLYYKSIDLNIKSKNFYDYLLACEYHNLLPKNSSIVIET
                     LRKLRNDDSHGYDIPQFEDMYELFTENEEVFVSIRNSCKK"
     gene            complement(54670..55050)
                     /locus_tag="JAM15_02155"
     CDS             complement(54670..55050)
                     /locus_tag="JAM15_02155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HAT6797078.1"
                     /translation="MRNIPNEIKNSIINVFPKENTLAIIIFGSYGTDKHTSESDIDIA
                     WIPIKKVPITELATKTEALRNILDIDVDLKIVTDNYTIALKKAILEGEVIYESKDFKD
                     YINKFYFENSDVIDILDWRDMYGN"
     gene            complement(55083..55391)
                     /locus_tag="JAM15_02160"
     CDS             complement(55083..55391)
                     /locus_tag="JAM15_02160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797079.1"
                     /translation="MNQIELDLYHDMVNIYKEADLQCNYKPTRFLQLINNKGALLAAK
                     ELINKEGATEGFTRLWECKRLDLSLEVLVLKEKYKELFTDEEREICINRLKDYGYKFN
                     "
     gene            complement(55424..56659)
                     /locus_tag="JAM15_02165"
     CDS             complement(55424..56659)
                     /locus_tag="JAM15_02165"
                     /inference="COORDINATES: protein motif:HMM:NF013579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HAT6797080.1"
                     /translation="MEYIKLREVCDLKNGFAFKSSDYIEASNVLNCRMSNIRPNANFD
                     AEYNPKYLPEDFSEKYKEYLLKDGDLIIAMTDLANDPKLLGVPTIVDTKGYKMLLNQR
                     VGKLILLDKSKVLESYLKYTLSLPQNKNYFKKFASGGLQINIGKEDILNLEIPYCDVR
                     TQEQIVKVLDKAQELIDKRKEQIEALDELVKSRFIEMFGNPVNNPRGWEFKRLNDIST
                     EILSGTTPKGGSQVYIEKGIIFLRSQNVWKNKLVLDDVAYIDEETHNSMKKSSLKNRD
                     ILITKTGRINTENSSLGRAAMFLGEDDSANINGHVYLIRLKKNIINEFVLFILTIDVY
                     REYIRSVCVGGIDKRQINKEHLEEFPIILPPVELQNEFVGFIKEVDKLKLKIEDSLKE
                     LEDNFNSLMQKAFKGELFN"
     gene            complement(56663..58126)
                     /locus_tag="JAM15_02170"
     CDS             complement(56663..58126)
                     /locus_tag="JAM15_02170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HAT6797081.1"
                     /translation="MITGELRSKVDKIWETFWTGGLTNPLEVIEQFTYLLFIKGLDEV
                     ETKNEAEATLLGVSFEKIFDDEHQHLRWSKFSNEGNSEKMYEIVQNEVFPFIKKLHGN
                     KESAYAKYMGDAIFKIPTPLMLSKIVDGISNLELSKDRDTKGDLYEYLLSKVATAGTN
                     GQFRTPRHIIDMIVRLIKPTPEDIIVDPAAGSAGFLVSSQQYLRDNHSSLFLVQGLKE
                     HFNNGMFYGFDMDRTMLRIGAMNMMLHGVDNPNIEYKDSLSEVNTDKDKFTLVLANPP
                     FKGSLDYEAVSADLLKVTKTKKTELLFLALFLRVLKIGGRCACIVPDGVLFGSTGGHK
                     SIRKEIVDNHKLESIISMPSGVFKPYAGVSTAIMIFTKTGTGGTDKVWFYDMKADGYS
                     LDDKRNEIKDSDIEDIIKRFDNLDGEVDRKRTEQSFFVDVEEIRENGYDLSINKYKEV
                     VYEEVVYDAPSVIIGRVRELEKEIVDGLEELERMLEV"
     gene            complement(58636..59505)
                     /locus_tag="JAM15_02175"
     CDS             complement(58636..59505)
                     /locus_tag="JAM15_02175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HAT6797082.1"
                     /translation="MALVTTKQILLDAQEGHYAVGAFNVENMEMVMAVIEAAEELKSP
                     VILQTTPSTIKYAGLDYYLANVKVASEKASVPVAMHLDHGSSFGLAMQALRVGYTSIM
                     IDGSHESYEDNISISKSVVDACMPSDIPVEAELGKVGGKEDDLDGGDGGAYTDPLEAK
                     EFVERTGVSSLAVAIGTAHGLYKGEPKLDLDRLSEIREVVSVPLVLHGGSGIPDEVIK
                     ESIKRGICKVNYATELRIAYSNGVKDVFNSDPEVIDPKKYGKKGLESVKDFVKSRMEV
                     CGCVGKAIGTVKC"
     gene            complement(59525..61441)
                     /locus_tag="JAM15_02180"
     CDS             complement(59525..61441)
                     /locus_tag="JAM15_02180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAT6797083.1"
                     /translation="MGKKMILGVTGCPTGIAHTFMAEEALKNSARELGCDIKVETNGA
                     IGVENKLTAKDIEMADAIIVACDKNVDMDRFNGKPVIEVPVKEGIHKANELIQRCIDG
                     KVAIRKGNLSSSKIAEEGNLSFGQKLYKDLMNGVSHMLPLVVAGGVLTAISFLWGIYS
                     FDPNSEQYNQIAATLKSVGGYSMNLMVPVLAAFIAQSISGRAGMLAGLVGGMISFDTG
                     SGFLGGIISGFLAGYLVKLFVHLLRKLPRQLEGLKSIFIIPIVSVGLVGVAMLLLGGP
                     CSALNNAMMNFLSGLQNSSPIILGIVIGCMSAFDMGGPVNKAAYVTGTMLLGQGNYLF
                     MAGVSAACITPPLVIAIASTLFKNRFTEEDRAAGLINYILGSTHITEGAIPFAAKNPL
                     KVLPVLMIASSISSILTYIMKIEVPAPHGGFLVLGLVNKPLLWVGCIFVGSLVGAVLY
                     MMVTPKVVNEKNTIENTNATKDGHKNESAESENVSNNISLYSEETVILDVKGKNKTDV
                     IDEMIGILDKSGVLLDKKKFKEEILKREEISSTGFGMGIAIPHAKTDAVKVPRVAVGV
                     SKEGFDFESEDGSLAHIIFMIAATDNGDNLHLKTLSQLSSKLMNEEFLNELLNSKTSR
                     EIVSKLNNEEIKSV"
     gene            complement(61444..62364)
                     /locus_tag="JAM15_02185"
     CDS             complement(61444..62364)
                     /locus_tag="JAM15_02185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HAT6797084.1"
                     /translation="MIYTLTTNPAIDMNISTNGIKRKLVNRTSNAVYSPNGKGLNVTF
                     VLGHYGIESKILGFFGGFSGKYIVEESEKRGFDVLPTWVEDTTRINIFLNDGSDEFKF
                     VNSGSYVNEKQKLDMLDKIQSLADISYLSISGSLPPGIDDNYYEDIFKICKNKSIKTI
                     LDISSPKLKELLQYNPYLIKPNDEEIKDIFGIIVRDEEDIKDVLKLLHLKGAQNILLT
                     LGEKGSYFYNGKSIYYASAQPVTVVSSACAGDSALAAFLSIWLENPEHIEEALKRSAA
                     TGASVAESNGIGNLENVENYIKNIRVRKVV"
     gene            complement(62466..63218)
                     /locus_tag="JAM15_02190"
     CDS             complement(62466..63218)
                     /locus_tag="JAM15_02190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAT6797085.1"
                     /translation="MIIELNKSNSENLTKTELEIIKFINENESILPELSIVEIAHETY
                     SSPATVSRAIRKCGLNGFNELRYRLTVKDENDDIQNMGDIINKSFIEAQRVIEQISLT
                     TLINIIKTINKSSKIYILARGLTEYVAKEFSLKLQLLDFNVVFINDPNIMKIKSKSIK
                     KDELIIIFSLNGNTIELVESAQNANLVGAKVITCCCSESAKLIKYSDLYIVGYKHEHI
                     SISEYEVSSRLPLYIISRIIIDYMVRYNNSEN"
     gene            complement(63515..64132)
                     /locus_tag="JAM15_02195"
     CDS             complement(63515..64132)
                     /locus_tag="JAM15_02195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797086.1"
                     /translation="MNVIKKFIFVILIINILGCGISLILQSSLGSDAITLLNEGIHIK
                     LGISYTIAGLIYNGTLLLIALLLNKKSLGLGSCVYVLVAGIFIDLYIYLLLDFNISSL
                     GIIIRIMSFIIGHILMCSGFAMLIKFDIGMSPLDAILIYIEGKFKYPYKVLKTIADLI
                     FLILGVYLGGNLGFGTVFSILCTGTTISIVSKMISVNKKRYYSSI"
     gene            complement(64220..65668)
                     /locus_tag="JAM15_02200"
     CDS             complement(64220..65668)
                     /locus_tag="JAM15_02200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAT6797087.1"
                     /translation="MSKFPKDFLWGGAVAANQLEGAWNEGGKGWCLADVHMYDKDRDI
                     SKHYESDMTVDKIKFAMKDNNGYYPKRNGIDFYHTYKEDLKLLKELGLKCFRFSINWA
                     RIFPNGDDLEPNEEGLKFYDNLINEVIDNGMEPIVTLLHYETPLNLVLKYKGWSNRKV
                     VDFFVRYAELILNRYKDKVKYWIVINQINLMYHESFNSVAFCVDQVDDVEEAKYQAIH
                     HQFMATALTKKLGKEINSDMMIGMMMADCTSYPEDCDPENVVFALKRNRIQYFFTDVS
                     FRGEYPAYIKRFFKENNINIVMEEGDDKVLKENTMDFLALSYYYSTTVSASKNTMNPI
                     DNVKNQYLKANPWGWAIDPKGLYNTLSQYYDRYQKPIMIAENGFGMHDKFEDGKVHDS
                     YRIDYLGKHIEQIGEAIADGTEILAYCMWSPIDIVSCSSQEMEKRYGFIYVDIDNNGN
                     GSKERYKKDSFYWYKNVIRTNGEELKEKVDSF"
     gene            complement(65699..66052)
                     /locus_tag="JAM15_02205"
     CDS             complement(65699..66052)
                     /locus_tag="JAM15_02205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAT6797088.1"
                     /translation="MTTEEHVIDEELVEVAMQIILRAGEARTEIKHALNDLERFDYKN
                     ADLKLAKAKEFMTEAHRAQTNIIQGEASGEKRAHSLLFAHAQDTLMTIFSELNITMSL
                     VGIVKSIEYKVNNSK"
     gene            complement(66081..67328)
                     /locus_tag="JAM15_02210"
     CDS             complement(66081..67328)
                     /locus_tag="JAM15_02210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAT6797089.1"
                     /translation="MGRLFMNKFIDLLSEKFTPVVNKITKNIWVQSVQSTIMKVLPMV
                     FVGSLVTIVSVLKNYISFLPDLSPINQYTFGLLGLFIAFLLPMEIMKNKKFESMSVVA
                     GLAGAGLMLMMIRPEITNEGAIFNFNRFGGEGMLVALVAGLFSGLIMSLFGSFSFFGE
                     DSALPDFVSKWFDSMLPIAVIMFIGWGLIYGLNFDMFEIIVRIFKPVSDIAQTLPGFV
                     LLNFLVVFLYSLGISGWVLSPITYAIQLSAIAANAAAVASGGLATNIYTYEVVQTGWI
                     TLGGWGATLPLVLMMCLSRAGRIKAIGRACIVPSIMNINEPVMFGAPVAWNPFLMLPM
                     WIGTVVISITTYLSMSMGFVTIPSKVFNLWYVPFGISTFMVNQDVRGLIVLAINIVLL
                     FMIWYPFFKAYEKEELKLESQEA"
     gene            complement(67336..67653)
                     /locus_tag="JAM15_02215"
     CDS             complement(67336..67653)
                     /locus_tag="JAM15_02215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAT6797090.1"
                     /translation="MKNIKVLLACGSGASTGFMATSMRKSAKKKGIEADIKARSESEI
                     DKYLPEIDCLLLGPHLDYMKDEIQKKADEYNVPVACISKTAYGRLDGVKALEEALELI
                     LNK"
     gene            67901..69814
                     /locus_tag="JAM15_02220"
     CDS             67901..69814
                     /locus_tag="JAM15_02220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAT6797091.1"
                     /translation="MKTSKKELFLNFIKTQHDWIDSSTLANYLNVSTRSIRKYVNEIN
                     STGEFILSSKKGYKVNLNNNCQTKVDSSENISPDNRLNLILKELIVNSNGINIFDLSE
                     ELFVSPATIEGDIVKANKFIGSYNLKIKQSKFLLKLIGNESAKRKLMSSIIFKETGSD
                     FLSLFDVQKIYQEYNLTKLKENIIYILKKYNLFINEYAINNILLHLMITIDRIKKNNY
                     IESVEVVNYIDNNNDISISRDISNFLESEYNLTLTSAELYYLVFQLTNKTTVLNYHEM
                     DTKSLPNYIDEHFVKLTKKIIKNVYDLYFIDLSDDEFVVKFTLHVKNLISRAKNNQVL
                     RNQIPQKLKDSYPLIYDISVYICNQIQILENIEIDEDEISYISLHVGSFFDRQKLLED
                     KILCALITPNYYDLQFKIVRDLEKRFNESIEIIQIFSDTHNLDFDNKVDMVITTLPIS
                     DRCPIPFVYVNPYLNRKDYDNIQSKFIQIKDRKNILTVQNHLEMYFSESLFMKNIYLD
                     SAKDYIKFMGNILYKNKYVKPNYIDDVLIREKMSSTAFNNNVAIPHSMKMDALKTGVC
                     LIVNDKPVKWGEEKVQIIAMIPINEKEKEKFNYIFESFIEILSEWNNVKELTKADNYS
                     SFMNRIAYLIQNI"
     gene            complement(69937..71091)
                     /locus_tag="JAM15_02225"
     CDS             complement(69937..71091)
                     /locus_tag="JAM15_02225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAT6797092.1"
                     /translation="MKILISIDSLKGSLSSIEAGNAIKKGILKVKEDAQVKILPLADG
                     GEGTVDALVQGMNGKKETIEVTGPIAKKVDATYGLLKNTSTAIIEIAQASGLTLVPTE
                     LRNPLYTTTYGVGEIIKEAINKGYRNFIVGIGGSATNDAGIGMLQALGFEFYDENNKL
                     VGLGGKVLNEIRHIKIENRLKELDECKFKIACDVNNPLFGKNGAAYIYGSQKGATSEI
                     IEELDNGLRNFSKVVKNYLSKDVANVEGAGAAGGLGFAFLAFLNSKLESGIKIILEEI
                     KLEEELKDADFVITGEGRLDNQTAMGKAPIGVAKLAKKYGVKVIGLAGATTEDAVKCN
                     EEGIDAYFSIVNRAMTIEEAMDKATASENMTATTTQIFNLITSIQQSKNM"
     gene            complement(71371..73986)
                     /gene="mngB"
                     /locus_tag="JAM15_02230"
     CDS             complement(71371..73986)
                     /gene="mngB"
                     /locus_tag="JAM15_02230"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HAT6797093.1"
                     /translation="MKKNVHIVPHMHWDREWYFSTEESRILLVNNMEEIMDMLENNHN
                     YPYYVMDGQTAILEDYLAVKPECKERIKKLVQEGRLIIGPWYTQTDEMVVGGESILRN
                     LLYGIKDCDEFGEYMKIGYLPDSFGQSAQMPQILNGFDIKYSMFWRGCSERKGTNKTE
                     FNWKSDDGSSVLVQILPLGYAIGKYLPMNEDELRTRMDKYLLVLDKGATTDHIILPNG
                     HDQMPIQKNIFEVIYKLKECYPERKFFLSRYENIFKELEKNEDIDTIKGEFLDGKYMR
                     VHRSIFSTRMDIKSANARIESKITNILEPLASIAYSLGFEYHHGLIELIWKEIMKNHA
                     HDSIGCCCSDKVHQEIMNRFFLAEEKVDQLITFYKRRIVDAMSCEMALDKLVAFNLMP
                     YDRNEIVSAQVITKMKAFEIFDRDNNNLDFEVVHKEEIDAGLIDRQIVHYGNYDSFMV
                     YTINFKDKIPAMGYKAYMIKEVEHMLEKAYEVCDMVDNDFYTIQVNENGTLKIFDKKL
                     NKTFENVLLMENGGDEGDEYDFSPLPNEKLIFNDNILANHTIKKNRFNNEIKINYRLK
                     VPKDIQARKNNRVDSFIDFDIVINVPNDKAIIDVVFNINNQARDCRVRTYIPTNIASK
                     FSVSDNQFGHIKRSVYDDAMEVWQQEEWSERPDSIYPMLTFVGLSDKEHGVAVLTNST
                     REFEIVGKKFDTIAITLFRSVGFLGKEEMARRPGRPSGIKLPTPDSQMIGDIKIDLAI
                     VTHEKSTLEANVANMAKEYLTKIQTYNKMPYNAMKLNQSEIEVDYSYSLLKETNKDLV
                     LSVVKKAEKQEALVVRFYNSKEETKSANIVFNKNIKTAKWINLNEKELESISIDNNSV
                     NVECLMNQVKTILIK"
     gene            complement(74130..76055)
                     /gene="mngA"
                     /locus_tag="JAM15_02235"
     CDS             complement(74130..76055)
                     /gene="mngA"
                     /locus_tag="JAM15_02235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS 2-O-a-mannosyl-D-glycerate transporter
                     subunit IIABC"
                     /protein_id="HAT6797094.1"
                     /translation="MEFKKITNENLVFLKQKIKTKEDAIKFLARKLYDEGKLTSYEEY
                     LEAVMYRETLSPTGFEKGLAIPHGKSKSVKEAAFAAMTLETPIENWESVDSNNKVELI
                     FLIAVPESEGGNTHIQILSELVTRLSNEDYMNMLLNSKTKKELFNNLDIKEKKEQIKE
                     EIRIQNESKKIVLAITACPAGIAHTYMSAEALIKAGKEIGVDVYVEKQGANGMVDPHT
                     PDIIKKADAIIYATDVAPKNTERFEHLPNIKTSVAAPLKRAKEIIYEALEVAQKQGKG
                     DYIEKSSDISYCEKSSWKKDVKSAILTGVSHIIPLIVAGGMILAFAVLASQAFGLQEL
                     YNQEGSWLWQLRKLSGGMLGTLMVPVLSAYMSYSLAEKPGLGPGFAAGLAADLIGSGF
                     LGGMLGGLLAGYIVKFLKKNIPAKGTLAGFVSFWVYPVVGSLVVGLLMLFVIGKPVAA
                     LNNGLINWLNGMTGINAILLGAIIGAMVSFDLGGPINKAAYTFAIGAIASGNFIPYAI
                     FASVKMVSAFGVTIATVLGRDLFSESEKEIGKQTWILGLAGITEGAIPFMIEDPIRVI
                     SSLVAGSAITGSIVAFFNIGLQVPGAGIFSLALLEGSMSGFIIASIWFFAAVLGAIIS
                     AILLIITRKQKNQRKIH"
     gene            complement(76185..76910)
                     /locus_tag="JAM15_02240"
     CDS             complement(76185..76910)
                     /locus_tag="JAM15_02240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAT6797095.1"
                     /translation="MEFYERAKKYEYKFTDTEDMIIEYMRKNKEEIVKLSIQSLADKF
                     FTVPNTIVRLCKKMEYDGFSQLKNNLKEELKNEDKEPKNGFESDIKKTLELIDYEKIN
                     KVADIIQKSRSIIVYGIGQNIPLCEILVKEIRGGHDNITYYSQRHEVLHDIGKLGEQD
                     MFFALSLSGETKEVIEAAKTAVNKGCKVVALTHICENQLQQIADISLYCYSTIKQVNG
                     YNISDKVPIMMIMRAIIEQYWLR"
     gene            complement(77553..77717)
                     /locus_tag="JAM15_02245"
                     /pseudo
     CDS             complement(77553..77717)
                     /locus_tag="JAM15_02245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439975.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cellobiose-phosphate degrading protein"
BASE COUNT        25657 a        13630 c         8208 g        30319 t
ORIGIN      
        1 ataaaatctt tttttctaat tatatacaat atattttcca ttatgttcta atcaatttct
       61 ttactatttt tacaacttta ttagtcatat tcataattat ttctaattag tgtttaacat
      121 tttatgtaaa atttataaaa aaatgtatat aaattaaaat aagtgactat actaaaaata
      181 tgatacggat aaacaataag ttcaacctat ctcccccaaa atcaagtgag ctacagtttc
      241 ccccaactgt agctcatttt cgtgtaattt aataaacatc tcaacaagaa ttaattaaca
      301 aaacccctta taaaaacata acatatatta aacaagctct tgattaaaac ttgagctttt
      361 ttaataaaaa acagaatagt ttattagata aggggttttt ttatgcaatt catggatgta
      421 tctaaataca ttgaaggtgc aaaccttaaa gttaaaacta aaaatggtga aactgttaaa
      481 agaatatatt ttaacaactc tgccactcca ttagttttaa aaaacgtagt ggataactta
      541 aactgtgaga ttccttggct tacttatatt aatgctccag gaataatctc agaaaaaaat
      601 actttaaaat atgaaaatgt acgctctact atcctcaaac ttattgatgg agacgaagaa
      661 aaggattctg ttatttatgt caaaaatgct acagaaggaa taaactcctt agcaaaattt
      721 tttaaagatg aaaatccaga taaatttgtt attaccacag caatggagca tatggctaat
      781 tacctacctt ttaaagttaa ttttcctaca aaagttgttg gaattacaga aaaaggagaa
      841 cttgatttct gtcaattaga gaatatactt aaaaattatg ctggtaatgt atctctcgtt
      901 acagttacag gagctagtaa tgtcacaggt ataaccactc ctatatatga aatagcaaga
      961 atagctcata aatatggtgc aaagatattg gtggatattg tgcaagtaat tcagcataaa
     1021 cctttttcaa tgatgccaca tgaatgtgat gagcatatag attttgttgt ttttagtgct
     1081 cataaatgtt attctccact aaatggagga gctctggtag gacctaaaaa attctttgaa
     1141 aaatttaatc ctgtactata tggctcaggt tctaccaaat ttgtaaatga taacaaaata
     1201 ctatatgcaa acgtacccca acgttttgaa gcaggatacc cagagtattt tggaactctt
     1261 gcaatgggaa aagcactgaa cactttaaat aaaattggtc taaacagaat ttcaaaatac
     1321 gaaagagaat tatttttata tgctaaagaa gaaatgagta aaatacctaa tataataata
     1381 tatggagata aatcaaataa tgtaattatc ccaaatatat cttttaatat aagtaatatg
     1441 tattacaaag atgtagcaaa atatttagtt gataactttg gaatagaaac tggagctgga
     1501 gtagtaggtg cagatattta tgtacaaaaa ttattaggta taagtccaaa agaagcatac
     1561 gtcagattta taagggaaaa tcctgtaggt cttgttagga taagcttagg aatgtacaat
     1621 acttttgatg aggtggatag ctttatacat gctattaaaa ctttggcttt taaataagct
     1681 ttttctattc ttttttatca ataaatagag agtagttttg ttttcacaaa aaaacaaatt
     1741 atatcaacag tcaatttcat tagcaattag acactcattt gtaactatac aaactatttt
     1801 acactataca aacaaaaaac tcattacaat gagttttttt gtttatatat gatatttatt
     1861 ttaattactt caatttactt taattacata tatgattcaa ttttgttttt taaattctcc
     1921 ttaggcataa aacctattaa tctatctaca ggttttccat ccttaaatat tagcatagtt
     1981 ggtactgtag atacttcaaa tttctgagct aattctatac tttggtctat gtccaccttc
     2041 aagaagtttg ctttttcaac catctcattt cctaaagctt catatattgg tgatagcatc
     2101 ttacaaggtc cacaccaagt cgcaaagaaa tctacaacta ctaaaccatc tttattttct
     2161 acttcattta taaattcatt attatttatt atttttacca taatatacat ctcctttatt
     2221 atcttcttga tactaatata ctacgcccta tataacagtt caattaggca cttttttgta
     2281 accgcctatt tttaatagat ttaatattat gataaataga tttataagat taaatattta
     2341 taagactaaa tatttctgat atattttatt tttttcttaa tatagttgac attttctccc
     2401 ttaaattata aaatcaaatt aataactaca taggtagtta ctaatctttt atcaaaggag
     2461 tttctatatg gataatataa ttaatgaatt acaaaatata ggatttacta aatacgaatc
     2521 tcaaatatac atatcattat taaaggaaag ccctttaaca ggatatgaaa taagtaaatt
     2581 atcaggtgta ccacaatcaa aagtctatga aaatataaca aagctattaa acaataatat
     2641 aattatcaat gttggaactg accctattaa gtacataccc ataaacccta atgaattatt
     2701 aaaaaataag aaaaaagaat ttgataattc tatggataat ctaaagaata gcttacagat
     2761 attaaataaa aataaaagtg tagaatacgt tttaaacata aaaggagata aaaatatatt
     2821 aaaaaaagca ttagaaatga taaaaaatgc aaaacaagaa attataattt cttgccctta
     2881 tgaagaaatt cttgaattaa aaaaagaact cctaattgct tacaaaaaaa atattaatat
     2941 tgaaatacta cttttagaaa acaaaagtct agaaggtctt gataatattc atattcatgg
     3001 aggtaataaa actacacttg aaaataaaat gctttacaaa ggaattattt tgattgtaga
     3061 taatgatgaa atattgacag gaaacttatc tgaaggcagt gaagccattt caatttggac
     3121 aaaaaactct aacattttat atattggagt tcaatacata aaacatgaaa tttatatttc
     3181 agaacaaata aaaggaggtt ataaaaatga ataaaattaa gattaaacaa gttgatgctt
     3241 ttacaactat accttttggt ggaaatcctg ctggtgtcgt tactgatgcc tctaatattt
     3301 ctgatgaaat taagcagaat gtggctaagg aaatgaattt atcagaaact gcatttgttt
     3361 cagagtcaaa tgttgcagac tttaaggtac aatttttcac accaggttta gaagttgatt
     3421 tatgcggtca tgcaacaata ggtactttcc atgcgctttt ggaagaagga aagcttaata
     3481 ctaataagag tatattttat caagaaacaa aagctggtgt attatctgta gagcttaagg
     3541 aaataaataa tgaaaatata tttatgatgg aacaaaatac acctgaattt gaaaatttag
     3601 ataattacag aaaagaactt gcacaaatga taggtgtgca tgaagataga cttcttgaat
     3661 atcctattat aaaggtaaat actggacttt ggtggcttgt atttggtcta aaatctttaa
     3721 atgatttaaa aaatatctct ccagatttaa ataaaattaa aaaatttagt ggtgataata
     3781 atataattgg tataactcca ttttgtatag aaactataga taaaaagtgt gactaccatt
     3841 taagatctat agcaccatat gttggagtta cagaagaccc tgtatgtgga actgggaacg
     3901 cttgcgtatc atcttatata gtacatcaca atattttaga taaaactaat tttattggtg
     3961 agcaaggtaa ctttataaac agacctggaa aggtatatgt aaatataact aaagaaaaca
     4021 atgacataac ttctgtaaaa attggaggaa gtgcttatac tattttaagt ggtgaaatta
     4081 tgtattaatc ccatacctaa taaaaacaaa taaaaatact agctaactaa agctagtatt
     4141 tttatttgtt atttttattt aataatcata ctctaacaaa tattataatt atatatatca
     4201 taatattgta tttagaagta aaattttatt tttattatta attagttata aatcaatcta
     4261 atacaacata attacagtag attaatctat aaaacataat aattacttac tgattattta
     4321 tcgtcctcaa caagtctact taatgtctta tcagataaga ataataatat cgctgcaaca
     4381 aatagtatta ctggaattat agtatatact ttaatcatat caaatttaag agtaaatgca
     4441 tatatatatc cgtatccttt accagctata aaagtagcaa atgtccatac tcccataaga
     4501 acacctagaa gcttcttagg tgcatactta cttacaaaag agttaccaag tggtgagaat
     4561 aacatttcac caagacttaa aagaatacca aacatgatta tccatagtat actagcttta
     4621 gcagtttcag gagctccaac tcctcttgaa aattctgcac caacaagcat taagaatgca
     4681 agacctaaga atattaatcc aagacctgtc tttttaaata aactcatatc tccttgtggt
     4741 ctactagcaa gtttaaacca taatgctcca agaactggtc ctaatactat acatacaagt
     4801 gaatttaatg agtcaaacca agcaagagga acatcaaatc ctccaacatt catgtttaca
     4861 aatgctgcac cataatcata aactgcaaga taagttagat accagaatac ccagaaaatt
     4921 acagagaaga atgatataag tataatagcc caaattctct tcttatccat gcttgtaaga
     4981 ggagacttat ctttttcttc aactttttca gcaactacac cttctttaaa aggtctcttt
     5041 cctgcatttc caaggaatct ccatccatat atgaaccata ttgcacctat tacacaaagt
     5101 acagctgcta taaagaaaca ttgagaaaat ccaagtacac cattttttgc aaatgtttta
     5161 aggtaaagaa taccaactgc tatagtacca ataaaagaac ctatattaac aaaagaatat
     5221 tgtactgaaa atgctgtatc aagttcttct tgactatcaa aaagctgtcc atttaccgca
     5281 gatacgttac ctttaaagaa tgcagtacca atcgaaacta agattatcat tgcatttacc
     5341 atagaaactg tagttgcaat agaaccaaga tagtaaccta cccccatgat aagcatacct
     5401 ataggtatag tatatctagc tcctatccat ctatctgata tatatccccc aattataggt
     5461 gcaaggtatg tgaatgcaac aaggttggct tgcattatag cagcttgtcc tttatctatt
     5521 ccaagaccac catgaactat agctgttgta aggaatatat atattaagta ctttgaagca
     5581 taatatgctg ctctttcaaa tgagaaagtt gttgagcaga tataaaatcc cataggaaat
     5641 ttacccttct tttttactgt tgagctcata attttaaatc ctttcttaat tgtattttta
     5701 ttttttacgt tttgtccaaa ttctttcttt tatgaaagat ataatgatat tattttgtaa
     5761 aacattttgt aattattatt aagataattg cgcatttatt tgtagagtac atattctcat
     5821 ggaataaaat taatacactt cttagttata aatttaaatt atataaattc gctattttca
     5881 gatatattta taaattagta tattctcatc taataccatg aaaaaacctt cgccatatgc
     5941 aattcttatt ttttacgtga tagtatttta caaactaaaa tccccctttt gtagcaactt
     6001 atgtaattac attctagtgc ttttttaaag gagtctcgaa taaagcaaca tatatttgtt
     6061 caaataatgt ttttatttac tttttaaata tatatattac ttcacccaac caattctcaa
     6121 cttaaataaa taaactacta tctattcaca gattagacct atttcttaca cattagttta
     6181 taataaacac tgtgaatcta aacataaaaa ctgttatttt aaagtaatta cccatatatt
     6241 cgctttgata ctatttattg aggttatact ctttatttat aatatattat ttataaaata
     6301 cctcaaaata tattattcat aaaatacctc aaactgaaaa ctttttcacg aatatttatt
     6361 tttcacctcc ccttttttat ttcaccatgt aaatcgtacc ataaatatac acttatatgc
     6421 aagaaaaaaa tctattaatc gacagtaaat aattagaaaa atttaaatta tatttgttaa
     6481 gtgtattata taaaatattt cctatgaaaa tataaattaa attaatgttc agaatagttt
     6541 ttagatatga aatcttgatt tttttattac tttacttatt tgttcaaata tatttttgta
     6601 tgcagtatat aataatcaaa ttatacactt cttataactg cgttgatttg aaaataatat
     6661 taatagttaa tagaagaaaa aatttaaatt aatttttaaa aaatctatta agttaattga
     6721 atactttttt atgtatttaa ttaattttat aaattcaatt attttctaaa tttaggtatg
     6781 ctttactata taaaaatgat tttttatctt aattttctaa atataagtga atgctatcat
     6841 tttaagtatc ttataagcaa tgtaactata tatctctaat aactactttt ttaacatgct
     6901 taaactattt ataagctatt atatttatgt attaacctaa taactttttc actaaaaaat
     6961 aacaatctat tcaaagataa actatagtac ttcttctact ttgtttcaat aaaatactaa
     7021 ataaatttcg tacatccaca atttttcagg ctacactata aatatacaat atttatctta
     7081 gttataagtt taagaatatt tttagtctta ttttgtcgaa tattttttta ataaaacttc
     7141 ataattctaa gcatattttt acactgtgtt ttcatgtaca aaaataatgc ttacaaataa
     7201 acaacataaa taaaacttaa ataagatgga ttctattcaa catagtatcc atcttattca
     7261 ttcaaaacct aaaaggattt tttataatat tatatatttt aaaatctaag taactcatta
     7321 tagtatcaat ttcacttaaa gcttacaata cacttattaa tcttgcttta tattaaaaag
     7381 tacaaaaaca tctacaataa caatttaaat ctttaagtga tatccatctc acacctaaag
     7441 gagtgggctc tccgcactat tctgtaattc ttcaatacaa tcattcttaa ttttttatat
     7501 aatttaatta tatattttat tttaccaaaa ccagcataca taaataatac ttaaaataga
     7561 ttaaataaag gatactaaaa cactttattg aggtatatga cttgaaatat atgaactaac
     7621 ttcattagga gaaatatcta aaatagttgc aaattcttca tttaataacc tttcagcttc
     7681 tttcattata ttatcatctg cttgatgtgt ttttttacca atagatttta catactctct
     7741 gttattatct atacttctta ctaattttat taactcttca catttaccac ctctgagtat
     7801 ttttttaaat tgctcacttc tcaatttttc attatctatc catgatgtat ccatattagg
     7861 aatatcattt attaatgaaa gcacattaat tttagaaagc aactttctca ttggtacttt
     7921 ttcattatct acaggaattt ttattactgt attattagaa taaataggac tcaatacata
     7981 atactctttt tttattccat ttgtaaatcg ttcattcgtt atatccatga ctttgcagac
     8041 tcctgtcata ccatacatta tataatcatc aatcttaaac aaaaacatca ccatccttaa
     8101 taaaaaaaat agttttgaca actaaatcca ccttgccaaa actatctgct atatattata
     8161 ttttaacaca ttttaagact taaatgtaag taaaacttat attattaaaa ttaaaaaata
     8221 cattaaccat tgattaatgt attttttaga tttttataac aagcatatca aaataaatta
     8281 atacagctta tctcctgtga atacctataa aattggtgct tggctattca ttgagtaccc
     8341 atcatttctt acatcattta tttctaatat ttcatcattt gttttaacct tagtaagttt
     8401 tttaactgct ccataaggtt cttttaatga aattttatct cctcttccag aaataaccca
     8461 taagatttta taccctctag gtattacttg tagtttattt tcacctttac catcagtaaa
     8521 gtagactaac aaattaatct ttttattatt agcatactca aatactggag aaaatctagt
     8581 acctccacct atcctaattc tatcttttat atctttttca gttctcactt tatatacacg
     8641 tctaatttca ttatcacatt ctataattgt aatttcatga ttatagtttt tcactatact
     8701 aagaacttct ttaatagctt gtttaaactc ttcatcacta atacttccac ttacatcaag
     8761 tgcaactgct atttctgcct tatgacttct aagttctccc ctcaaatcta aacgatttgg
     8821 ttgtcttcta tttcttcttg ttatagtctt ctttttatta ttttcaactg ttcccattat
     8881 tctattaaga tataaattcc atggcaattc acccttacta tttttaagtg atgatatcat
     8941 actttctaaa taagcaggaa ctttaccttt ttgagaactg ttaataaatt tttcagtaaa
     9001 ttctctaagg gtattttcat ctatctcatt ggattcatcc catatatcat gagttctttc
     9061 ggggctataa tcaatttcta catctccata tttatcacta tcatcttcct caccatcttc
     9121 atccacttcc atcaaatcta attcagtctg aatcttttct acataatatt caaaaggttc
     9181 atatggttca agttttaagg aatattttaa atttacccac tctaaggtag ttgcatatgg
     9241 tggtaaattg tttaggaatt tatttactac tatatccatt gccatattaa ttgccaatgt
     9301 actatacttt ccttttaact cctttgctct catcaaatgc atagataata tatgatgaat
     9361 ttcatgttta attgtagtct ccatttgctt tatgtcaagc gttaaaaaga ttattggatt
     9421 aaaatatata acatatttag ctcccttaaa attcacacct gtaggactac ttatatcaaa
     9481 tcttatttct cttgacatct gaaacaaaaa atatccataa aaattatctt cttcttccat
     9541 aagacttaaa ttcactttat ctacaagact aaaaaactca tacttaaaat cttgtggtat
     9601 atccatatca aacttctcat tagcacgatt tgcctttagc atagaatgag tatttataat
     9661 ttcacttgct ttattataaa gctcttttgc ttgtttatca aaataatttt ccatacatta
     9721 tccccttatt aagctataag attcaaaata tgattttaca aaatcttcat tttctatggc
     9781 ttttttatat acttcaatat aactgtttct aatatccttc ataataccta tcattaaatc
     9841 tacaggatac atttttaaaa attcaataaa tctattaata tagtggtttg attcatattt
     9901 atcattctta atatttaatt ctaagtcttt tagaatgttc atagctgata gataaagtct
     9961 tgtatgactc tcatttttta ctctttctac aatggactca tcaatagatt ctcctaaaaa
    10021 aacatcttca taggatatta atggttcaga gtttgattca ataaaactta taaattcttc
    10081 tgcaataact ttacctacat taccctttac aacatttaaa aatactgctc taggaataga
    10141 attatttttt tctttataaa ctttataaat tttagatact ctctcataac ttctaggagt
    10201 agctcttaca tcatcttcat ttattttatg cagatattct ggaaaagtgg aaataaactc
    10261 gataactttt ctttcaatac cctcatctat tgcccatttt atccattgtg tatggtcact
    10321 ctccatattt aaccaaacaa acctattttc ttgggctgca tccatatcta ccacttgata
    10381 atcaaaatct gaaccatatt tacttgatgg attcattgct gctaaaatct ttacatcatc
    10441 atgcagttta tatccattaa tttctctatt taaaattaaa ttcataagtt cttgctgtac
    10501 tgtatgctca caacgattta tctcatctat aaataaaaga actgtcttac ttctagatat
    10561 ctcttcatca atttctctta atttgttatg aacagcatac actgttgttt tcttttcagt
    10621 cttatatcca ttagaattaa ctcctacata agattctata gttggaagac cacctatttc
    10681 accctcttta agtaagtttc catcaataac aattaaactc caatcatttt ctttggcaag
    10741 cttatttgct aaagctgttt ttcctattcc actttcacct actattaaag gtacttctcc
    10801 agtggataat attaagtcaa cgctttttaa tgtgtctata aaattcattt ttctctctcc
    10861 tacataatct ttaatttctc atctacagct attttttttg ctgtcttact tccatattta
    10921 taaataaaca taattttatc tattggtata ctttcactat ttctatctat aacactacaa
    10981 ttcaaaaaat ctctaatata cttttcctca acatcttctt tggataatac ttcttttaat
    11041 acactctcta attcatcttt agatactttt ttcagaatgt acttaatcac taaaatattc
    11101 acttttagaa attccaacat tttattttta tctaaatcag ttataaagct aatagctgct
    11161 tcattatttt ttatagctat aagttctgca ttataactag gtgaatctat atatctcaag
    11221 gcatcataac ttattctcac tgcctcctct tgtacacttt cataaggttg ttttataaac
    11281 tttatcgaat cataattttt tcttactgct aatagttgta attcttcact tggatttcta
    11341 gcatatttaa ttgcccatcc tgcttgattt atagccattt caataacttt atcagttggg
    11401 tttttgatat aatccagtat actccatccc tcatttactg cttttatcat catatcttct
    11461 gttggattat ctataaattt aattgctcta atattattat ctattgctag ttcttgcatc
    11521 tctctggttg gattatttat atattctagt acaagcccat tttctttaat agctaacaat
    11581 ttcatttcat cagttggatt atctattgta gctataatat tgggattatt ttttatcatt
    11641 tcaataactc tcaatttttc cataatgtgc ctttctttct ataattattt ttatatctat
    11701 attaattata ataatctatt cctatttata taattgtttc ttattataat taatatactt
    11761 tttaatcaaa tttaaacaga ataattatac caatatataa aaaaatttct aaaaatcaat
    11821 aaaattaagt tataagcacc aatatatttc tatcatttca acaagtatac aattagatta
    11881 gaatctaaca ctagtaataa aaaaattact ttctcaaagt agatataagc ctcgttttat
    11941 ggttcaaatg atgaaggata tatttgattt catgcaaaaa gagtgcctaa tgaactaaaa
    12001 agttcatttt aagacactca tttttttata taaatttata tagtttttag tcgttcgcat
    12061 ctaaccactc agttaagact tttatatatt tctcattttc ttcaacgaat ggcatatgtc
    12121 ttgaatactc aaataactcc cacttactat taggtattct atcatacata gtctttgcaa
    12181 tatatggcga acataaatct attgctccac tagttactag acaaggctct tttatttcat
    12241 gtaatctatc tgtaaattca tatccagaaa gagttcctgt aggagaaaat tcattttgtc
    12301 cccatcctac aatatatgct tcagaacctg attttttagg tcttctcagg cactctggag
    12361 aatcttctgt cacttcacct gcacaataca tttccataaa tctttctaat gcatcattat
    12421 attctttact agagtaatct ccagtattta ctgcatcaag caatgctttt tggtcaacct
    12481 cactcatata tgatattctt cttttttgtt ctttctccca aagttttgca gaagaaagag
    12541 tagatgaaag gatgtaagac ttaatacctt ttggtttata ttcaatagca taccaaatag
    12601 cctgcatacc tccccaagat tgacctaaca gatgaatttc atcaagccct agatgttttc
    12661 ttagttcaat aagctcctct atccaagtat ctgcattaaa taactcagga tgcccttcta
    12721 caaaggaatt tccacaacca atttggtcat acattattac ttgtctacca ctttcagcta
    12781 tcttatccaa tacttcaaaa tagttgtgtg tagaacctgg acctccgtga agtaatacta
    12841 atggcttctt cccttccgta ttttctccta ctatacggta atacgtttta aaacccttaa
    12901 aaggcatata tccttcagta attttcatgt ttatctcctc caatttgtaa ttataagcaa
    12961 taatcaagtt cattaataat actatttaaa acctctcata cgtatttaat tatgtctttt
    13021 aatctttata cctactttta taaatagtat aacataaaag ttaaaaatct ctatactaaa
    13081 ccaattataa aatcatatta actatataat tttatttttt aataagagta tatacatatt
    13141 ttattatttt catttgctag tttaaaagca attttaaatt ttcttactat aataaacttc
    13201 ctctttatgg tctcatgtta gtctctaaat ttaaaatttc acaaaaaatt ttcataaaat
    13261 aaaattatat tgattgtatc taagcaaata gggcaataaa ataattaagt atagttactt
    13321 acctttcaag caatattagt tttatgttag aattttatta tattaattta caggaggttt
    13381 gcatttgaat aatattaatt cacttaaagt aataaaatta tctcttggat gttctctcgc
    13441 tatatttatt gcttggctat taaaattaga atactcaatg gttgctggag ttatagtact
    13501 acttacagta aaagacacta aaagagaaac tctcaaaggc tccattggaa agatttatgg
    13561 ttttctttta tgtactattt tttcatattt atgttttaat attttaggat ataatttgac
    13621 ttcattttca atatttatat ttataattat accactttgt tttttgttaa atattcaaga
    13681 tgttgttgct atgtgtgtag tcatagcatc ccattactac cttcaaggag aaacttctat
    13741 caaatggatt ttaaatgaag ctggaatatt tgcagtagga actggaatag gtgtcttaat
    13801 aaatatgtat attccaacaa atatacataa aatctatgaa gttcaaaaaa agttacagga
    13861 agaagtgagt attgtactta tagacattgc agatattatt gtaaatccaa aaaaggaaaa
    13921 tggatatagt agagatttat atacattaaa ttcacttatt gacagcagta tttctgaaac
    13981 ttacgataat attaataata ctttattaag tgatactagg ttcttcttag agcatatgga
    14041 tattataaaa agccaacggg atatcttaga aaatttgtat agttatgtat ctcaactaaa
    14101 ttctacacca ccacaagctc acattctatc tgctttcata cataaaatag gttatactga
    14161 atttgaagct gaaacaggca atcttcttct tgaagaattg aagagattaa tgcttagtat
    14221 gaaaaaccag cctctacctg ttgacagaac agagtttgaa aacagagcta ttttattcct
    14281 atgcttgact gagttaaaac aatttttagt taatcgtaaa catgctcaga tgcttagaga
    14341 taataatttt tataaataaa aaggtgagaa atccagcagt tgacctgact acaaaatatc
    14401 agatatatta ttaaatgcgc ccctagtaag agggcgcgat gtttataact tattctactg
    14461 tcatgattaa atcattattc atatcgaata tacattattt gaccaagtcc aatattagct
    14521 ttttcatcag tgatttctat tttaatagtc acatcatttt ttttacagta ctttgctaat
    14581 tctgcaccag aacgattttt accactaaaa tctaaagaaa atggcttatc atatttaaaa
    14641 ggatattcaa caggttcacc ttctggtgct aatgcaaaca tcccatatgg tgtgttcata
    14701 aatcctatta cagcaattgt aagatttgat gggtctaaat ttgatttact acctagaaat
    14761 gtaactgtat tcactgatga attaattaca acacatctaa caccttcata cattacatgt
    14821 ttatccttta tatctccaaa ttttccaaca acctttgccc cgtcttgatg tggtaacata
    14881 gtgtgcttcc caggtggtgc tggtttttgc gtttgtgcta ctgctccaac tgttggatat
    14941 gctgtcttat caaatggtaa tgggtgccta agactcttgt atatgatatc ctttcctgct
    15001 gatttattag catcaatatc tacatgatac aaacgcccat caccaaaacg tataagattc
    15061 cactggtggt catttgatgt gctgtggaca taataagatt caattcccat agcgtcacac
    15121 aaagctttca tgctcctagc cattcctgaa catgcacctt ttttagtaac caatgtatag
    15181 gcagtattcg ctccttctac tgcattccag tcaacatatg ttgtgttatt tttaatgtga
    15241 ttataggcaa ctaaaatctt agcatctgta gtcatgttct ttgtaatttt attgttcata
    15301 aaatctgctg ttgcttgtgc tactgagttt agttgggctt gtgacagctt tggaccatat
    15361 acgctattgg ttccagtgac atagcttttt ggtgtttttg ctgttacctc tttggctgtt
    15421 ataccataaa ctgtcatact catacctgag attaaaacca ttgttgtaat caataacttg
    15481 gtagctaact tcctaatttt cttcatactt aatattctcc tttataaaac attgttactt
    15541 cctattctct accattaata aaattaattt aggatttaaa aaggtggatt gtcaacatgt
    15601 atatttctcc attcatacat tcgtgaaata tttaaatttc aaggaaaatc taatagatat
    15661 tttctagata atttgtatac aatacaactc gcaaatcagg gtgtttgctg ttagtttgag
    15721 aaaatgatga tgattaatat attcggaatc tttgacctat aataaatacc attgtcttca
    15781 atcattaata atggtaagag taaagagaat tatcaataat acagttaaaa tcaactttgt
    15841 atacatttca tacattctct cccaataaca ttatacttct tataatttgt atattcaata
    15901 cgttttctgg gaaaatatag gatatatcta taaaaatata aaaaaggagt tgaacttaaa
    15961 atttgattaa aaaaatcaat tttaagacaa ctcatttgta ttataaaaat gctatatatt
    16021 attattaagt aagtcaatat tttagatatt tatctatttc ttattgactt acgcttatag
    16081 tctaacttat ttgtttagtt gatatataac ctagttttaa gcattattaa tatttaaata
    16141 atcaagtatc ctttttgttt cttgtagttt ctgttctgcc tcatttaagt tttcttgaat
    16201 tatagaaata tatattatat ctatcaacgt aagcattgct attcttgaag aaatagctcc
    16261 ttctctaagc cttttttcta tatttggtac tactagcttt aaatcactaa tcttactaag
    16321 atgattgtca ctatatttag ttatacaaat gaccttacat ccttttaatt ttgcattttc
    16381 tatagacttt attacttctt ttgattctcc agagtaagat attgctatag ctatatcttc
    16441 tttatctaca tttgaagata ccataagttg tgtatgacta tctaaagagg taaatgcctg
    16501 tttatttatc cttaaaagtt tcatctgtaa atctagtgca actaaagccg aaccacctac
    16561 tccaaatata tatacatttt tagcctttat tatctgttca actgcttctt ttattatatc
    16621 tttttcattc aacaaccttg tttggttgat agtctctatg tttttgtttg taattttgtt
    16681 tataacacta tctatattac aatcatagtt ttcatctaca tatgtgtatt cattttcttt
    16741 gcccatcaaa tctttagcta tctcaatttt taaatcccca aaacccgaat atcccatttt
    16801 tctagaaaac ctaactatac ttgctgtact tgtttttgag tttgacgcca attctgatac
    16861 agaaagctta cttatagcct ctgtattatt aagtatgtaa tcagctattt ttttatctac
    16921 ttccgttaaa tcttcatata tctgttttaa ttttagaatg caactcatac tctaccacct
    16981 ctacctattt actataatat ttcttcttag caagtaaaca tgctcctaaa tctggagtca
    17041 acactggtct cactatacca aatctcgttt tattcaaata ttttttaagt ggctctaata
    17101 ttaaatctcc tgacttaaac actccacctg aataagatac ctttatcttt gtaccttgtt
    17161 caaaatgatg ctctaatcct attataagcc tacttaattc ataagctgca tcatcaaata
    17221 ttttactagc agtattatca ccttcaataa ctgcttttaa acatatcgta gcaaactttg
    17281 ctatttctat tctatctcct tgtattccat catttacata ttttattatg tcataatcat
    17341 tctctatatt aagatgtctt tttattaaat catataattt tgtttttgaa caccttccat
    17401 cagactgcat tgtgaacatt tttaaggtag ccattcctat ataatacgct gaaccttcat
    17461 ctcctaatac atagccccat cctccacatc tgtgaagatt cccatcttta tctaaagcct
    17521 gtgctattga accagtacct gcaattatat ttataccttt ttccccattt aaagaacctg
    17581 ctaatgctat ttctacatca ttacctagag tataatttat atgactatat gcattttttg
    17641 ttgctacttc taatgcatac aatacttctt ttatttttcc atatccagca agtccaacaa
    17701 atgcatacgt tatttcttct acatttatct tagcatcttt acaaacttct tccaacccag
    17761 ttattaataa tttcgttaga ttatcaaatc ctatttgatt ataatgacaa gttcctttgg
    17821 ttatggttcc tactatattt aattcttcat ctactaatgt aaatgttgtt ttcgttcctc
    17881 caccatctac acctaaaaaa tacatactat cctcctacaa tatctttaat aattctttca
    17941 atacttaata tctaaaaata accttccaat gctgtttttt taatattgaa aggttatcag
    18001 tactattatt tattttacaa tttttctatt gattttaaag cttcacttat ataaccttct
    18061 tgtctatcta ggatactctt tgcactatcc ttatctaaac cactttttat cataaatata
    18121 gccaatttaa cgctattatc tgcttcttct aagaattttt ctgcaacgtc atattttaca
    18181 tttgtagcta tcattattat tctttttgct ctttcaacca acttttcatt tgatgtctta
    18241 acatctacca tcaagtttga gtatactttt cccatcttaa ccatagaagc tgttgttaac
    18301 atattacata ccattttttg agctgtacca cttttcattc tagttgaacc cattattact
    18361 tctgccccta ctataatgtt tattggtaaa tccgcttttt tactcatttc actattcgga
    18421 ttcatagtta ttgatagtac tgcacacccc aattccttag catactccat tgcacctata
    18481 acataaggag tccttcctga tgcagctata ccacatataa catccttaga tgtaactcct
    18541 ctatctatta tatcttgctt tccaagttct ttatcatctt cagcaccttc tattgcttta
    18601 aatattgctt gatttccacc agctattata gcttgaacaa gctcaaaatc cactccgtaa
    18661 gttggaggac attctgtggc atctagtatt cctatcctcc cactggtacc tgctcctata
    18721 tagaataatc tacctccctg cttcattcta tctactatta tattaacagc ttttgctata
    18781 ctctcctttt gttcttcaac agcataggct acagttttat cttcgttatt tattaattct
    18841 attatgccta atgtatcttc tttatctatt tgcaatgtat tcttatttct accttctgta
    18901 actaaatttt ctaaagtttt tattaacata tcatttcctc attttcttaa tattaaattt
    18961 ttaaacacat tttaattcca actttcataa ttatattttt ataataaatt aatattttca
    19021 taataaatta ttttgttgag ggtttaaaat taaacttttg ccatggttta atataatcta
    19081 atataaataa ttcttctttt cttatatatc ctactacatt cgatttacca ctgtttttca
    19141 tatcagtcaa ggctatttgt aactcccctg aataatgacc atattcacta ctttcaatta
    19201 ctatatctcc tctttttatt attttaggag tattaaatag ttcaaatttg tatcctttat
    19261 atttaacacg agattgagta gaccttatca gactgtcaga tatgtcccct ctattaaaat
    19321 gtatttcttc aaagagtatc ttcttctcaa cttctcgtat attttcctct attgctacat
    19381 caaatgtaac catatctttt ctcatagaac ctaatacctt tagctcctca tatgttggat
    19441 aacaatttga tattattata tcatttatat tattcatagc tattatatgc tttacttgaa
    19501 tatctatagg tagatttctg tgcatctcaa ttgttggaag ccatcagtta caggccatgg
    19561 tccaaatgtg gtttcatttt gacttgttac aaaaactgcg gttcttaatc catacttatt
    19621 aaatctttct gtacatttta taaagtgttc taaatttaat ccactatatc tatgtggata
    19681 aaagttatga catcctgtca aattttcttt atttggttgg tagtccatta ttgtatctat
    19741 ataattagta ttattactca tattgatttc tattttaaga ttttgaggat taaaagtcat
    19801 taatgcctct tcagaacctg taaatcccat atcaagcctt attccgtctg ccttcgtctt
    19861 tttaaaaaaa gtcaaatctt tgtagcttat ttctaattca ccaaatactc tgggatttac
    19921 atcaagtatt acctcaaaac ctttaaactt agcgtattca tttatacttt taaatttttt
    19981 aattatattt tctttagtat ctttaactga taataaacat gaaaatatac gtgtaaatcc
    20041 attttcagca gctttatcta tataatcata tatttcctta gatgctgttt tttctggata
    20101 aattgatatt cctaatcttc ccatctgtgt catctcctta tatcctatat gtgtttaaat
    20161 ttatttcgaa ttacacgaaa cttttttaaa aatttggtga aaaaaagttt catatatatt
    20221 tataaaaaaa gaaaagttta ccttttcttt ttttataaac aatcaacaaa atatcttcgt
    20281 tacttattta ataactgtta tactttgaaa tttatactaa tctaatatag tttttaattt
    20341 ccaatatagt ttctaattaa taagcttctt gctcttcaac tttttcttca tgaagcaacc
    20401 tcttatcgta catcttgaca aatggatagt aaattattat tgatatagct atacataata
    20461 agttaagaac tgaagctctc caatctccac cagtggctaa atatgcccct actggtcctg
    20521 gtaatgtcca aggagcagta actactactc tggatactaa attagcactc atagcaaacc
    20581 atgaaactgt tgccattact attggtgcca caacaaatgg tattattaat attgggttta
    20641 atactattgg tgctccaaat attattggtt catttatatt gaatattgct ggtattacag
    20701 ttgcttttcc taaagacttt ccataagctg attttgctct aaatgcaaga agtaaagcta
    20761 agcctattgt agctccagaa cctccaatcc atataaacca ttgaaaaaag ggttcagcag
    20821 caatacctgg aactgcttga cccgcagcat atgaagctgt attagcatct aataattgta
    20881 tccataaagg tcttgccaat gaacctatta ttgatacacc atgtattcca aatgaccaaa
    20941 aaaacgttat taaaaatatt agtataatta ctgatggtaa tgtgtcagtg gctgaaacta
    21001 atggagttac taatttagct atgaagccat gccaatcaaa ccctaggaaa taagtaacaa
    21061 tagccattaa aattattatt aatgcggctg gtgtcagagc ttcaaaagac cttgtgactg
    21121 atgctggaac tgcttctggc atggttatct tgaatttaga tttgtcagta aatctataaa
    21181 tctcaacacc tattatagat gttacaatag caacaaacat tgaacctcca ccaagattag
    21241 ccattggcat ttgccatcct tgaggaattg aattatacca agctaaaagt tctggactct
    21301 tttcaactat ctttaataaa tcaggggtaa gaccctctat tgcagtagga actattgtca
    21361 aaaggaatgt agctgtagct aataaacctc ctgtcaatcc atctaactta tatgactttg
    21421 ctaaactata acctatgcca aatgtagaat atactgatat aataaaaaat gtcattctat
    21481 atggtagtaa tattgtaact gcattttcct ttagatactg agttaccccc catgaatctg
    21541 gtaatggagg aaatgctaat atcaagaaaa atgacccaac tattataagt ggtaatgaag
    21601 ctacgattcc atctcttaca gctcttaagt gacgttgttc tgccaatctg gccatagaag
    21661 ttgataattt actgtctaaa aattctgtaa atttatctag catcttttct ctccttaatt
    21721 aatatttatt tttattatca ttaaaatttt tataaaatta actttcttct aacctaacaa
    21781 cactgcaact actatttact caacaactct tgaacttgtt ttaataattt tggtcctcct
    21841 aatggactat aagcttgtgc ttgtattaat gcacatggta cactagcctc atcagcaaaa
    21901 gcttttaaat agtcaaatct atgtctgact tgtggagcta ccatagcaat atcccatcca
    21961 tttttaactt cattctcaaa ctcttgagta ccaacagcca aaacatctat atctattcca
    22021 ttttttgctc cttctttttg taatgcatta actgctatag cacttgacat ccctgatgaa
    22081 caaacaaata atactctcat attgattccc cctgtttttt tatttctttt caatcattat
    22141 agcatgtatt tttgattaca ggaatacgtt tgtatatatt ttttcatatt ttacattttt
    22201 aattgtaatt ttatttcatg catttatatc ttgctttaat tgctttattt atctaatcat
    22261 tcttttgtct aaaattacac actacttaaa atactcatat cttttcttaa aaaagaaaaa
    22321 agactatctt ttattaacat aaaatagtct caatactttt ttaaatatgt attcctttat
    22381 atatccagaa gtaacctatt attgcaaatg ataaaacaaa taaaatatac agtctaaaaa
    22441 atcccaaaga aaaacctctc ttagtttcaa caaagtatct tgtatatgca actgcaaaag
    22501 atgtaattaa tgaatttcct ataacaactc caaatctatt atctattcca aatatagata
    22561 ataacaaagg aaaaactaca gtacttacta gagatgaaac tattagtatt aatccacttt
    22621 taaaacttat agttggaata ttataatctg ttctttgatt tttctccatt tctttcttag
    22681 tatttttatt actttctgta ctttttgcat ttttataatt attatttttc tttcttttct
    22741 tttttttatt attagacatg tcatttacct ccaaaaggtt taggtgttat attccctaaa
    22801 ataactttat ttttagcccc tgttgcagat attacattag aaaaagaatt atttaatgtt
    22861 tcattgccca agattacaaa tgccaaagcc tcctttgcat cagaagaata cccatattca
    22921 tcttgagtta atacttcaac ttctaataat aactctttta tatatcctat taaagttaga
    22981 ttatgagctc ctccacctcc aattaataaa gtatctacat taacctttgg aagtatgaag
    23041 tttttataat tataatatat agcttttgcc gtaaacatag ttactgttgc tatcaaatca
    23101 tatttatcta catgtttata tttgttaagc atgttatcca aatagacttg tccaaatacc
    23161 tctcttccag tgcttttagg tggcgcttga ctaagatatt tatgactcat caaatctttt
    23221 aacatttctt cattaatttt accttttgat gcaaagtatc catttttatc atactttcta
    23281 ttaaataatc tttgacttac tccatctatt atcatatttc ctggtcctgt atcaaatgca
    23341 aatacatcat ctatgttaca tgatttaggt attatagtaa tatttcctat tccaccaata
    23401 ttttgaagtg ctaaattttt atttttatca ctatataata aaaattcact atatggtact
    23461 aatggagcac cttctccacc tgctgctata tccattactc taaaattaga tattaccttt
    23521 gtatttgttt catatgctat aactgctggt tcacctattt gaagcgttga agatacaaaa
    23581 ttattataac ttcttggtat atgaaagatt gtttgaccat gagatgcgat aaaatccaaa
    23641 tttgctatat gaaagtttgc tttatgacac actgatttta cagctttact aaataaatat
    23701 ccaagcttaa aatttaagct acagattaaa tcaacactcg attcctcttc tatacagcac
    23761 tttcttattt cgtcttttat atctttagga atttctagag ttataaattc tatttgctta
    23821 actttagtat ttctaccatt cccactaatt tcagctagta ctgcatcaac tccatctaag
    23881 gaagttcctg acattaaacc tacactatac atagttatca tccttttaag tttatagtta
    23941 ttcctcccca aatcaaggta ttaagtttaa taattttaga attaatctta tttcctcttt
    24001 aattacgata atttactctt acgaaattaa ttgagttaat cttatacacg ttttttacct
    24061 tagctaaatc ttacattaat ttattttcag tgtcaatgta atgccatgta attttttttc
    24121 acaaacaaaa catattctct ctccaaaaac catattaaaa tagttgctac aaataaaaaa
    24181 cataccaggt acctatctga tatgtttttc atatataata attattattt tataatatag
    24241 atagagcatc atttaaggca ctaattaaat cttcactatt ttcaagaact aaatttattc
    24301 ttattgtata tgtcgatttg tatatgatga tagattttat agtctaataa cctaactatc
    24361 taggcttaaa taatccgata tatcataaaa gtagatatta aaaattgtgt atgaaccaat
    24421 tttcgaacat acctcaatct catgccctaa actatctatc attttcttta caaaatacat
    24481 ccccattcca gtagacttat acaattgatt tcttccattt ttccccgtaa atcccttgtc
    24541 aaaaacccta gatatatctt cctcatttat acctatacca aaatctttta tagataatac
    24601 cactccattt tctaactttt ttgaattaaa ttcaatctta ccaacttcct ttgaatactt
    24661 tatagcatta ttaataattt ggtctaaaac atatgacatg catttagaat ctgtgtaaac
    24721 atcattttct aattcattca aactaacttc tacattattt tttataagca aaaatgaatt
    24781 attttttata gacattttta ccaatttttc taaattaaat ttatttataa atacatcttc
    24841 aaacatagtg ttgcttctac tactgtacaa aatagagttt actaaaaaat ttatctttgc
    24901 aacctgattc ttaatatcca aactatcttc tatgctactt aacctatctg taattatact
    24961 taaagaagat attggaattt ttatttcatg aacccattta gctatgtact catctaattc
    25021 ttttaatgat tgtttataag tctctatgtc actattattt tttattttta agttttctat
    25081 aatatctttt attagatttt cttcaaaaga ttgtccatca attaaataac tgtctatttc
    25141 accactattt tctatacaat tatataaatt tatataacta tttctaaaat ttttataatc
    25201 tataacaaaa aataccatta ttataaacag cactaaaaaa tctaagtata ttaattctga
    25261 atatctattt tttaaaatat ctatagcaaa taaatagata tttattatac taactacaac
    25321 taaaggtaga gcaatatact tagacctacc ttttaaatat tttactagca ttatattata
    25381 tatcctatcc ccttcttagt ttttataaaa tcatcaaaac ctagttcttt aactttactt
    25441 ctcaatctat tcatatttac agtaagtgca ttgtctgtca caaactcatc attatcccat
    25501 agagtcatca taagactttc ccttgataca accctattct tattttttaa taataatgtt
    25561 aaaattttta tttcgttttt agtcaactct atacttttat ccttatactt atgttttata
    25621 atccctttcc ccacatcaaa catcaaatct tcacaataca aaatactatt agaatcacta
    25681 taattataga ctcttcttat tataccattt attttggtaa ccaatatgtc tatagaaaat
    25741 ggtttggtaa tataatcatc tgctccatta tttataccca ttattaaatc catatcagaa
    25801 tctcttgatg ataaaaatat taatggtaca tttgaaatag ctcttatttt ttcgcaccag
    25861 taaaatccat tatataatgg taaatttaca tctaaaagta ctacatctgg ttttttatcc
    25921 ataaattcat ctaatactac ctcaaaatca tcaattaatt ctactttaaa tccccatttc
    25981 tcaagtgcta acgcaatctc ttttgataaa tcaatatcgt cctctactaa taaaattcta
    26041 tacatttgta tattctccat tatcctaata tttcactatg ccatgaatta ttaatatcat
    26101 aacatatttt atataaattt attacccaaa ttatttagtt aatcaacaag gagactctta
    26161 ttacaagaat ctcctttctc tttattaata tatcaactaa tttttataca ctacactctt
    26221 aaacttatta acagatactg ctccatatat tacgaatatt atcaaacata tcactaaact
    26281 tagtatatat ataccagata aatcgctcat caataaatct cctgctaatc tcaatgcaaa
    26341 ataactagat atagttgcac ttaacattgg caaagtataa aatatagcta cttctttaag
    26401 tatagctcta tttatatctt tttctgtagt acctattttt aataaaatct tgtatttctc
    26461 tttatcttca tatgcatcac tatatatttt catatatatt atacttccag ctacaattgc
    26521 aaagactaag aataaaaaca caagcactac atatgcaaac ttcatccatt gactctcacc
    26581 ttgagcttta tatccattct gaatatatcc attttttaaa cttaaattct tttcaatatt
    26641 gttgaacatt acttggctat tttcttcttg aaataccttt gcaccataaa aatatacttg
    26701 ttgaccctta tctcttagtt taaaatatgt atcatcattt accactataa tactttgatt
    26761 aagtcctgtc cctaatactg gaacttttac ttctcccctt gaaatattat ataactgacc
    26821 atcaagtttt gtcttggctt cttttgtagc tattgatgct atcgtttgag gactttttag
    26881 ctctattaca ttatttccac taactaatct ttcaccatac tcttttaatt ctttatcatt
    26941 gccattcact ttaagagtat tacaaaaatc actatatttc attatagtat ctgttgtatc
    27001 ataagcttct tttatatctg ttttctttaa gattgttagt tctggattta cggagtactt
    27061 tatcttatta gtatctttta ttatgttctc tatttgtttt ttattcactt catctttatc
    27121 cattgaaact atgctaatag cgtacacatt tctttgttct tgggcattct tatgtatatg
    27181 cttcatagca actgaagcac caagagttga tattgttgta gttataatta tagctattat
    27241 agcataagtt ttatagtttt tatttaatcg gtagtttata ttgtttattg caattatatt
    27301 atttccatta aataatattt ttttattttt gattataata tcaaatataa caggcataac
    27361 tgatttgaat aagccataag tacctactat tattatacct ataacaggta gtacactagt
    27421 tatatctcca gttcttatat tcgtagaaag atagtatcca tatcctatta ctataattga
    27481 tactatagct aatatatata tacctattcc tacctttggt attttttctt gttttttaga
    27541 tatattgatt agatttatta cactacttct acatattgtt ataaaacctt ttacagccat
    27601 tattataaat atagaaataa agattaaagt agcatatagt atagcttcta tgctaagtcc
    27661 attagatacc tttatattaa atccagataa ctttattatc actacttgaa aaaatctaga
    27721 tgttattatc cctataatta ttcctgttat acaagaactt attcctataa gcatattttc
    27781 tacaaaatat atttttccta tagtatataa atctaatccc ataaaggaca atattccaat
    27841 ttctttagac ctattcttaa aaaatatatt tgttgcatac catataaaga aaaataaaaa
    27901 tactgatagt atcattatta cagctactaa cactgatagt gtaaattttt tattttcctc
    27961 ttgtaacaca tttatagcat ctccatatct taataattca aaattagtca gcacaactac
    28021 tgaaaaaacc atagatataa aaaatgctag ataagttctt atgttactct taaaattatt
    28081 ataagcaatt ccaagtatac tcacttacat ctcacctccc atagaggcta gcatatccat
    28141 aatttttcca taaaattctt ttctactatt tcctttgttt aatttacact ttatatttcc
    28201 atcatttatc atatatactt catttgaata acttgccgtt agagggtcat gtgtaatcat
    28261 tataatagta gcgttgtttt ctctgtttat tttttctaat gattctaaaa gttcatatgc
    28321 tgatttagag tctaaggcgc cagttggttc atcagcaaat atgactgctg gatttgtaat
    28381 taatgaccta gctgctgcgc ctctttgttt ttgtcctcct gataactgat atggatattt
    28441 atctaaatga ttttctaatc caaatttttt agctatagaa aataccttag cttctatctc
    28501 cttgcttttc ttttttccta atgctagagg aagtgctata ttgtccatta gtttcatatt
    28561 gtctaataga ttatagtctt gaaatataaa ccctattttt tctcttctta attttgatag
    28621 ttcattattt tttacttttg atatattaat tccatctagt attatttctc ctgaagtttg
    28681 tttgtcaagt gtagacatta aatttagcaa tgttgtcttt cctgcaccag atggacccat
    28741 tattgctata aaatcacctt cattgactgt aagagatata ttttttaaca catttgtttt
    28801 aaatcctttt attccataat cttttgatat attttttatt tttaatattt ctttcataat
    28861 aatagcctcc agttgctaat tttttaatat atatttattt taaaggtttt atataaataa
    28921 atccttaagt aaatattaca ttttaactgt tagcattaca cttttgtaac atatggaaga
    28981 ctattataat tatagtggaa atatcttaaa ataaaagcat gattcacttt tttgtataaa
    29041 caaagaaaag aagcccctaa gaagcctcta atctatacaa taattcttct ctataaaaaa
    29101 ccaaaaatac aaccttgatt gtggcaaata caggtactat aaacaagtga tattactact
    29161 atatattaaa acaattattc ttgaagataa ttcaataaga ctatcaagcc ataagctaag
    29221 catccaaaaa gacttaatat cattaatgta taattatacc caatattaat actcaaaaaa
    29281 ccagcaacag ttggaataat cagagatgaa cctcccataa atatacttaa agctattaat
    29341 tggctactac ttctaagttt tttaggagaa acttcaaata ttaatctttt tgaagtaatt
    29401 aaaattaaag gagtagaaaa cacttgaaaa acacacagta taataatgat atttgaatca
    29461 tttgttaaag caaataatag aaactgaact gttatcataa tagcacttaa ttttaataag
    29521 tttaaactgc tatatttttt taataaataa gaaccagcca gatatgttgg tatctctaat
    29581 aatgactgta aagaccactt taaagatatc tgagaatttg tagcatttaa agctatcatt
    29641 ttatctatta cagtacagtt atttgctacc accattgagt ataataagaa taaaatacat
    29701 actagtaaga tatatttttt atcttttaat aattcaataa tatctttatt agttacattt
    29761 attttcttat taatcttttc aatatcaggt aataatagta tatttataat aagtaatact
    29821 acaattaaac caatcgctac agataatcca aaatatgaga atctaagaat caagtaagat
    29881 gctaccatac ttccaatagc ccatccaatc gacccaaaag tcttaataaa tgacaaataa
    29941 ttattaatat tatctccaca acctattatc catgtatcat ataaactaca gcaagtattt
    30001 aataatcctc ctgataaagc aacaagtaat aagtatatta taaaagttgc agattcagta
    30061 gaaaacataa taactgatgc aattccataa actgataaac taattaaaac aatttttttc
    30121 attgtttgat acttatcagc taatactcca aataataatt gaaataatat attggttatt
    30181 gcatagctcg ataatataat tcctctttca aacgctgagt aacctaattt tgataagaaa
    30241 ggtgtgaatt ttgttgaagc aaaggcaaaa ataatatatg agaaaaaata gaatatgata
    30301 aatttaaatt taatcgcttt attaatcata atcaatcaaa attgataact ttaataccac
    30361 tatttccttc ctgatttaag tttgaaagat gatattttac cgtattagga ttctctacaa
    30421 taactaaagg aatatataaa gtattttcaa gtaacttatt atcaatttct actaactttt
    30481 cccccatatt aacttcttga ccttgtttaa cttctaattt aaagttttct ttttttgttg
    30541 ttgcactatc caatccaata tgaataagaa tttgaacatc attttgcaat ttaattccta
    30601 tagcatggtt agtttgagca ataaaactta ttactccttt agtcggtgat ttaagaatat
    30661 tgtcctttgc tatcatagca aatccatctc ccattacctt agttgaaaat actttatcag
    30721 gaatttctcc aagattaatt atttttccat caatgtatga attaattgta cttgcttctt
    30781 tttttctttt aaagaacatt atagacactc ctctacataa ttaactttat tctaattatc
    30841 attacaaata acgatattaa gcatactgca attgaggaaa aaagagcctt atagctcttt
    30901 ccccattgta gttctttaat actgcttatg atttgtttaa ttccaacaaa tttataaata
    30961 taggtaaaca tgataacaat agttattgtg taaatttgga atatctgccc taataagact
    31021 aaatagaaag caatcatgtt ttcttttatc tctttattct tttttatatt gtaaataaca
    31081 tatgcactgt atactgcact aaagttagag attaaattta aacttgcatt aacatcattg
    31141 tttaaaagtt gtgaaaatga aatgtttgta aataatgatg tcaattctaa atacactata
    31201 tataaaacag gtaatattag aaaacaaacc ataaccactg aaagaaatat attttcatct
    31261 tttaatactg ctgtgatatt ttttatttta tttgttatca tgtttttgtt ctccttattt
    31321 aaaagttggc cagaaatcct tattagccac aatcatttca tctaagattt cttttgctac
    31381 ttttgcactt ggaacagttt tgctcatagt aaacgactgc cataattttt gataactttt
    31441 ttctatccat gcttctacag ctaatttttc agaagcaact tgttgttcca ttaaaccttt
    31501 ctggaaagtt ggaattttac ctatagacat aggttcaacc atatcttttc caacaaggca
    31561 aggaatttca atcattgcat catctgcaaa attttcaata gctccattat taggaacaat
    31621 cagtaaaaat ctttcctgag tattaaatgc taatgcacaa gctaattcaa caataaattg
    31681 agaatgttca cttgcatcaa accatgtatc ccttgctgtg ccatttttta taattctttc
    31741 acattcttcg aatgtatcct tttctcttct atccataatt tcatttgctc ttgtataatt
    31801 tggattagca tgttcaacag tttcatcagc cattaaataa tattttaaat aagtattagg
    31861 taatgtagtc ggttctattt ctaataagtc ctttgctgct ctcatagttt ctaaccaact
    31921 agattctttg tgttgacctt gaggtgtaaa ttcctcatat ccttttttag cacaatattc
    31981 ctgtaattta ggcattaaat catttccttc tttgtcctta atacttgtcc accacccgaa
    32041 atgattcaat ccataatatc taacatcaaa gtctttacga gaatttaaac ctaaaattct
    32101 agcaaatatt tcctctaaac atactggcat atcacaaata ttaataattc ttgaatttgg
    32161 tcttaataca cgacatgctt ctgcaactat agctgctgga tttgaataat taagcatcca
    32221 agcatttgga gaatattttt ccatataatc aatcatttcg attattggac ctattgttct
    32281 taatccatag gcaattccac ctgccccaca agtttcttga ccaacaaccc catattttaa
    32341 tggaattttt tcatcttgtt cacgtaaagc atataaacca acacgaattt gtgccattac
    32401 aaaatcaata tcagtaaatg cttcttctgg atttgttgta taactaaatt taatttctgg
    32461 atttttctct ctaacaatta ttgcacatgc ttcagcaact tttctttgtc tctcatcatt
    32521 attatcatat aatttaattg attcaatagg aaatttagca acactttcaa ttaacattgt
    32581 tacaattcca gcagtataag tactaccccc accagcaatt agtatcctct gtctttttct
    32641 ttccatcttt ccttctcctt tataataaat tttcaaattc ttctcttaca cttggtactg
    32701 aaagcccaat aataatctga atagcttttc cattatgcac taaaccatgt gcacctacta
    32761 ccttaaaatc ttcttcttta gaaataattg agtcatcctt caaggttaat ctcaacctcg
    32821 tagcacagtt tgtaacatct acaacatttt ctgctccacc aactaatttt atgtattcag
    32881 atgcttgttg agaggcttta ctcaatttat ttcctttttc atctttagtt tctaagtatt
    32941 catttttagt atatagtttt gtttcttcac tatcttcctc tctaccagga gttttcatat
    33001 caaacttctt aattaagaaa gtaaatacaa agaaccagat aaatgaaaat ataatcccta
    33061 caacaacttg aacaacatat accttccagt gatacattcc aagaggaagc caatttaata
    33121 caacccagtt aataattcct ccaccaaaat caccaacaac tcctaaggca aacgaaatcg
    33181 tttgcaagca tgcatctaaa aatgcatgta ctaggaataa aagtggtgct acaaataaaa
    33241 atgtaaattc taacggctca gtaattccag ttaatactgc agtaagagta gcaggaatca
    33301 ttaaacctaa tacttttttc tttttttctg gctttgcagt tacatagaaa gcaccaaata
    33361 cacctaatga accaaacacc ttcgataatc cagataatga aaatccgatt ggatacattt
    33421 cctttagagt cttagctgaa gtttgaaagt cctgaatatg agtagcccaa tatactgatg
    33481 taccacctgg aacaacaaca ctatcataac aaattggtgc atatacaaaa tgatgtaatc
    33541 cagttggtat taaaatcttt tgtaagaatg cataacacca aactcctata tttccactat
    33601 ttataaaaaa cgtttgcaaa tgtctaataa cattttgaat atgaggccaa ataaaacaag
    33661 ttaataatgc aactggtatc ataacaaaga aacaaattgc aactacaagt gatgagcctc
    33721 taaataatcc aataaaatct ggtagttctt tatcataaaa tctattatga atataaatga
    33781 caatacctga tattaacaaa gcaccaacca taccagtatc taatgtttta ataccagcaa
    33841 tgcttacaag tccacttcca gcacttattt cagctgcgaa atcaactcca aagctttttc
    33901 cccaaaaact taacatagaa cctacaaaat aattaaaagt caaatacgtt gctaaagcct
    33961 ccatacaagc tcttgcttgt tgcttttttg caagtgctat tggtaaagaa atagcaaata
    34021 ataatggtaa ttgattaaat accatccaag ctccactaga tattacaccc caaaattggt
    34081 accaaatatt ttctggtgta gcaagtgaac ccataattga ctgattttga aatacaattg
    34141 agaatccaac cattatcccg gcaaaagcaa ataatagtgt tggtgtaaac attgcccctc
    34201 caaaacgctg tattttcttc atcatataaa ttactcccct cctcatattt ttagtttatc
    34261 tttggcctta gatatctatt attttaacag gttaataaat atatacaatc tttagggtac
    34321 atttggagct tattcacagt caaataagtt tttgcacatt tttatgttca aattctcata
    34381 aaaaaaagaa tgactacaat ttgcaatcaa tcccttctgt aatcattcta tgccttttat
    34441 aaatactata tttaataaat aataactcaa tcaatataaa atataacatt gtcaatttat
    34501 aactagggtg catttgtaaa aatgagatat tagtcgctga aatataaatt gattcatcac
    34561 ttaaatcagt caatgtatta tttttaaact ctgtaattga aattatttta gttcctatta
    34621 attttaatct tctagcaata ttaagtgtat tctcattctc accacttagg gatataataa
    34681 tcataacatc atttttactg acaatattgt aaaaagaatc atcaaatgtt cttccctcaa
    34741 aatcatatat tatttcttga catgataaga acattctctt tatctgtttt gcaaccacat
    34801 tttgaatatc acctgaacca taagcgtata ttgttcttga ttcataaaga agtttacaca
    34861 atgcatcata atctttattt ttttgatctt caacatactt aattattgaa ttacatgcaa
    34921 tatcaaatga ctgattttct atgacatgaa ccttttctga ttcccagctt aataatactt
    34981 taaactcact gaaacctttt aaatctaatt ttttaacaaa tcttgtaata gttgcacgag
    35041 acacattaca tttcatagca agttcattta ttgacatctt actacaatgt tttttatttg
    35101 cagttatata tttccatatt aataaatctg tatcattcaa tttattataa tttaaaaaaa
    35161 tcatttcttc taatctcata aactattatc ccctttaatt aaaaatcgtc ataaatatta
    35221 taccaatatt caacattaaa ttacagcgta ttcttatatt tactatttag cccataaaat
    35281 tgactataaa aaatactgct ataattgatg tttaaaaaaa tgtagtttta attttattct
    35341 tttatctaat aattaatatt ttcaagttct agtgcttttc ttatgcaatt atcatcttta
    35401 aaatcagcag tccttttaca atcttttact ttaaattctg gaatagtttt aaattcctca
    35461 tcacatattc cattcttatt taaatacata caacttgcca ttctaactat tagaccacta
    35521 ttttttaaat taaacaatac agggtctata caccctccat ctccgccagt agtttcacca
    35581 actaaagtcg caaatttagt ttctttacaa aacattgcaa atgactctga tgatgaatat
    35641 atttttctat caacaagtaa gtatatatta cccttaaatt ttgaatcatc tgtagatttt
    35701 atagtatagg aagtatcttc aaaatcatta aaatctttta taatttcttt aggtgcattt
    35761 tcctttacac ttgctggtaa attttctaca ggatttaatt ttatatttct tgcatttgta
    35821 tattttttta ctatttcatt attatttcta taaattctat aaccatttat tttgacatca
    35881 ttttttatga gtttagatac gattccctgc caatacctat cacttccacc taaattacct
    35941 cttatatcaa taattaaagc tttatgtttt tctaaagtgt taatataatc tccaattatt
    36001 tttaaatcat tatttataga gccattcttt gatgacattg atggtaaata catatatcca
    36061 atctgaccct taataacatc ctttaaaatt aattcttttt ttacaaaaat atcatctggc
    36121 atttttattt taagattcat agagtcatat ctatccacaa cttttttatc attaagaaaa
    36181 tcataccaat cattattaga gtatgatttc ttaaaaagtt catatctttt cttattatct
    36241 attacttctg tgtgtttatt atttaaatca gataatatag atgacagttc ttctataaat
    36301 tcttcatcat tttcagtgtt ttttattcgt tttgtatatt catccttatt tgctaaccaa
    36361 tcaatattat taagcctctt atttacacct agatatggat atcctgtctt tacaacatta
    36421 tacacataat taaagtcatc caccttttcc tcttcagaca actgattctt ttgagaataa
    36481 gtagaattac ctaataagat tataaatgct aaaataatta ctaaaaataa tactttcttt
    36541 ttcatgtaat tctcatccac tttcagattt tatattttaa tacattgtat cattatttta
    36601 ttatcaccta aacagttaaa agaaattctt gaagatatat tccactatta ttctatttaa
    36661 aaatttttat ttgtattttc aaaattattt catgaaagtt ataaaataac aattatattc
    36721 aaatatctat tttactgcta tatcctgaaa gtaaattctt atcagtgata tactaaaaaa
    36781 gatatgctaa aaaatttatc cattataatg acttaaattt agatacttta ctgattttta
    36841 tttattagtt gagaaagata ttgataatta aaaatattga taactataga aatgattatt
    36901 ttttatagaa attttaagga tataaactaa ttatacttaa gtctatatcc ttaatttatc
    36961 atgattatga gaatttttac aaatacttat ctttgtccgt tttagaataa aaacaagaac
    37021 atatcctgtt attttattca aacatccaag tttaattact acacaattac ttattagaaa
    37081 ttgtatctac ttcatatata tatctgttaa gtatagcttc tagcatttct tgtcttccag
    37141 acttattctt tataactggc atttgcagtg cataagattc taactcttta aatccaacct
    37201 taccttctac tatatcctta cctatacctt cactaaaact tgcatatctt tctttagtaa
    37261 agttttcaaa tacctcatct tctaataatt tatgagctat taataatccc tttgcaaatg
    37321 tatccattcc tgcaatataa gctaggaata agtcttctac ctcaaaagat gctcttctta
    37381 ctttagagtc aaagttaaat cctcctggtg ctattccacc ttgctttaac acttcataca
    37441 tagcaagtgt tgcatcatat atatttgttg gaaattggtc tgtatcccaa cctaataata
    37501 ggtctccttg atttgcatct atactaccta aaacattgtt tattcttgct atatttaatt
    37561 catgttggaa agtatgtcct gcaagtgttg catggtttgc ttctatattc attttgaagt
    37621 atttatccag attatacttt cttaaaaatc ctaaaacagt agcagtatca aaatcgtatt
    37681 gatgtttagt aggctctttt ggcttaggct ctattaagaa ttggccagtg aatcctattt
    37741 ccttagcata atctacagcc atttgtaaga atcttgcaaa gttatccatt tcaagttctg
    37801 tattagtgtt aagtaaagtt tcataacctt ctcttccacc ccagaataca aaattttctc
    37861 ctcctaagta cttagttatt tccatagctt ttttaacctg agctgctgca tatgcatata
    37921 catctgcatt acatgttgta gatgcaccat gaacaaatct tggatttcca aacatattgg
    37981 cagttcccca taataacttt atacctgtct tttccatatt aacttttata tactcaacta
    38041 tttcatctaa tatcttattt gtctcttcta aatctcttcc ttctggagct atatctctgt
    38101 catgaaaaca gaaatactca attcccatct tagacataaa ttcaaatcct gcatcaactt
    38161 taatctttgc tatctcaatt gggtctgtta tattattcca aggtctctct actgtgccta
    38221 ctccaaatgg gtcattaccc tctccacata aagtatgcca atagctcatt gcaaatctta
    38281 agtgttcttt catagtctta ttacctacca cttgttcagg attgtagtat ctaaatgcta
    38341 actcattgtc agattttact ccttcaaatt ttatctgtcc tattccttta aatatttcac
    38401 tcatttcatg tcctcctaat attttacaca tataatatat gtagtatgtt ttcttaattt
    38461 aaaactattt tctatcttta tttttctttt taagttattt taattattta tttttggaat
    38521 taactacttc atctaataac ctaaagtcat ctttcaaaga tttgtatatt cttttataca
    38581 atctatgata tatcttgtat gtatctacat tttcacttat tggttctaat ttagttgaag
    38641 tttttattat agcatcacaa gctttttgta tattttcata tattccagcc cctactaatg
    38701 caagaattgc aactccaagt gctggtcctt cacttgaatt tatagtatat acatcttgat
    38761 taaacatatc tgcttgcatc tgtctccata ctttactttt tccacctcca cctgaggctc
    38821 ttacttcatt aacgtctata tcaagattct ctattatatc catacagtct ttaagactat
    38881 atgaaacacc ttccattatt gatcttgcga tttctttttt agaatggatt ggagataatc
    38941 caaagaacac acctcttgca taagggtcaa gatgaggagt tctttctccc atcatatatg
    39001 gtaagtaaag caatccatta catcctgttg gtacttgact tacttgatta tttataatct
    39061 catatacatc ttcacctaaa gaatttgaaa cttccacttc actttgacag aaattatctt
    39121 taaaccattt taatgacaat ccagctcctt gagtaactcc cataacatgc catgtatttg
    39181 gtattgcatg acagaaagta tgaactctac cttctttatc aatttttggc tcttttgtat
    39241 aagcaaatac tacacctgat gtacctatag tagatgaaac tactccatct ttaactattc
    39301 catttcctat agctcctgct gcttggtctc cagctcctcc taccactatt gttccttctt
    39361 taagccctgt caaacttgct acatctctag tcacataacc tgtaatctct tgtgattcat
    39421 aaactttacc taaaagattt ttatctatat ttaacttttc tagtacttca tcgctccaat
    39481 ctctttttct tatatcgagc aactgcatac cacttgcatc tgatacctct gtagcatatt
    39541 cacctgtcaa tttgtatctt atataatctt ttggaagaag tattttatta gtatttttat
    39601 atatatctgg ttcattgttt ctaacccata atatctttga tgctgtaaat cctgtaagcg
    39661 ctggattagc agttatttca atcagtcttt cttcacctat taaatcagtt atctcctcac
    39721 actcttttac tgttcgttgg tcacaccata ttatagagtt tctcaatgtt ttaccttcat
    39781 tgtccagcat aactagacca tgcatctgcc ctgataatcc aattcctttt atacattcac
    39841 tgtttatatt tgaactttga actacttctc ttatagattc gactacagct ttccaccaat
    39901 catttgcatc ctgctctgcc caacctgatc tctcttgtat aagaggatat tcatatgtac
    39961 aactttttat agtatttcct agtttatcaa ataaaactgt tttagtacct gatgtaccaa
    40021 tatccacacc taatacatac tccaacttca tccctccttg aatgccactt cataactatc
    40081 gttttcctat cctaattttt ttatatttta ggtatatttt acttgcttta tttttgttag
    40141 tatattaaac taacttatga actaataata aaatatttaa ttatctttgt caatgcaaaa
    40201 taacctttta tttttgtgta aaaagtatta caatattatt ttaaggagga atatcaaatt
    40261 ggttactgat aaatacacta ttcgagaaat gaatgaaaga ttggtacttg aacaaattat
    40321 aaaaaatggt cctatttcta gggcaagtat agcttctact ataggattga ataaagcaac
    40381 tatatccgct attaccaaaa aacttattga tgaatctcta gttcatgaaa taggaattgg
    40441 aaatagtact catagtggcg gaagaaaacc catattatta gtatttaata aatgcgcagg
    40501 gatttcttta agtatggaca ttggatacga ctatatattt tcttctctat cttacttaga
    40561 tggaactatt ataaattcta agaaattaac agatatacaa gtaagtaaag acaatgttat
    40621 acaattgata gatgaaatta taaatagtta taacatatcc aaaatagaca ctccttataa
    40681 ggtaattggt cttactttgg ctatacatgg gattacttgt gaaaataaag tattgtttac
    40741 tccatattac aatcttaatg agattgactt atatagcatc cttagcaaaa agtatgactt
    40801 tcctattcac atagaaaatg aagcaaactt aacagcttta gctgagaata ctttttcaac
    40861 tgtacataac tcactactta gtctcagtat tcacagtgga tttggttcag gcattataat
    40921 aaataataaa ttatatagcg gcagaaatgg tatgagtgga gaaattggtc acactatcat
    40981 catgcctaat ggtaaactat gtccttgtgg aaatcgtggc tgtttagaac agtattgttc
    41041 agaaaaaaag gtatttgaac agctttcttc tttagaaaat attcctaaaa tagattctga
    41101 tatagtaaag caactatatt atgaagataa ccagaatgcc aaaaaagtta ttcatgagtt
    41161 ttgtagttac ttaacaatag ctataaataa tgctattaca acttatgctc ctgaaataat
    41221 atatttaaat agccaaataa ttagtgatat ccctgagata ttacagatta caaaagatat
    41281 gttagttagc tcttttaaca aaggaataaa tatagaaatt tcatcattag ggtctgaggc
    41341 atctctatat ggtggctctg ccgtaaatat caagagcttt ttgaatatac aaaatttaac
    41401 tttaattaat gaaatataag ggttatgact atatacagcc ataacccttt aaattataca
    41461 ttctaaaatt agatttatta tatagtttat gcaagattag ctatattttt taaaaattgt
    41521 atatcaatta agtattaaca taagtatttt gttttaaata ttaatataat cttcctactc
    41581 atcatcagat aataaacttg cattttgttc aaccatagaa atattatctt tacctatttt
    41641 ctctaatttt gctgccaatt cctttgtatc taaaaaagct gattcaataa ccatacctaa
    41701 atttagccct gaaataattt taattcgact gtcattattg gctactaata aagcagcatt
    41761 gcatggagtt ccacctagta aatctgccat tataattatt tctgaacttt ccttgtacac
    41821 ttctaaagct ttttttaatt tttctattgt tccttctatt ccatcatctt gtttcatatt
    41881 tacagtagga taatctatag aatcccctat tatcattttt gcagaattta agacttcttc
    41941 agccatattg ccatgactca tcaaaataat actattcact ttaatacacc tctttaaatc
    42001 tataagatgt ctacaagata agttttctta tcatcaggcg tcattatagt tgtaatttca
    42061 attccttcat ctaaaagtct tttaaatgct tctttctctt cttcagtaac actgatatta
    42121 ggtcttagca ctgttgtatc ttttctactt gacatatttc ctacatttat attatgtatt
    42181 ttaaatcctg cctctacaaa tggaataagg tccacaggag acttaacaat taataataca
    42241 ttttgtcctt catactttcc tgcagtaata ttttttatag cagtctcttc tgtaattata
    42301 gatgacgcta tacctgcagg tgtagccatt cttaaaactt gtttttgaac agaattgtta
    42361 gctactgcat catttactac cattaatctt gtaacaccca atttattact ccacatagtt
    42421 gcaacttgac catggattaa acggtcatct atacgaatat ttttaatacc tttcatttcc
    42481 atatctaata tcatcctttc cttattttaa aatacctaat gcatataaaa ttattgaaac
    42541 aaccattact cctaaaatta agtatatagg ttttatattc tttttaagag cccaataaac
    42601 aatcacaact aaaattgcag gaactaaccc aggcataatt tggtctaata tttcttgacc
    42661 tttcattgta aaatcacctt gttgaaagtt caaagcaaca ttagctttta caactgaagg
    42721 tattaatgca cctacaacca ttaaacctaa aatagatgta ctctcagtta aaatctttaa
    42781 acttttttca attgaagata ttagcttagt acctgatgta taaccagcat taaatagtgg
    42841 tatacttaat aatttcaatg ctacactcac tacaatccac agtaagattc caaatggact
    42901 tccatctatc gccatattag ctgctatagc tccaaaaatt gtccacggaa taacgacaaa
    42961 taaactatct cctaaacctg ctactggtcc catcaagcct gttttaattg aagcaacagc
    43021 ctcttcagtc tcttcacttg ataattcctc cattgctaca ttaataccca aaatataagg
    43081 ggcaacccaa ggattagtgt taaaaaattg taaatgattt aatacagcac tttgtaactt
    43141 ttctggatta tctttgtata ctacttttaa aaaaggtagt actgcataac agtatgccaa
    43201 ggcctgcatc ttctcataat ttgaagaaac agaactagta aaaaaccagc gccataagac
    43261 actttttttc accttttcat ttgatttatt taatgatacc ttatcactca tcttcgtcca
    43321 tacctcctac tacagtatat tgttgttctt gattttccaa attctttttg taaattataa
    43381 gtgcaatcgc tccaccaatt aaagctacac ctaataatgg tactttcata tatactgcta
    43441 aaacaaaacc aattactaag taactaaaat actccttagc aggaagatat ctaagtaata
    43501 atcctatccc tactgctgga agtagtcctc cagctactgt taaaccacct gttaaccatt
    43561 caggtgtata tttcaaaatg gtattaatta aagaaggccc aaatattaca gatagagcaa
    43621 ctggaatacc tgttgtagct gctgttaata gtactcctaa catttgcata taggttatat
    43681 ttttataatt tcctttttta gctccatctt ctgctttatg aactagccat ataccaatag
    43741 tatttctaag aacatctaat tgtaccatca ataaagcaac tggaatacct atagagattc
    43801 ctacagatgc ttcttgctta gtcgtaatag ttataaatgt ggctactata cttgctgttt
    43861 gataatcagg tattgatgct ccaccaaagt tactaatacc taatgataat agctgtaatg
    43921 tacctccaat atataaccct gtatttatat ctcctaagat aagaccagta ataaaacctg
    43981 ctgttactgg ttgatatgtt ccaaacattg ttgaattttt ttcatagttt ataaaaaatc
    44041 catatagtac gattaataat aattgccata attgtggctc cattatgatt tcacctctcc
    44101 caaaatattt tttagttctt taaaattata actggaatct tgctttagga aaataggaat
    44161 ttcttccagt gggcattcaa cttcataagt tttcccacct tcataactaa ctccactaaa
    44221 tatattttcc catgtatgtc cttttggtaa atatactttt ctacttctat ctttataatt
    44281 cattattgga gctaccaaaa tttcatctcc aagcatatat gtattatcca cctcccaagt
    44341 tttatcatct tcaggaaatt cataaaataa agttctcata actggtgttc catcttcatg
    44401 cgcttctttc atcagttttt ttaaataagt ttttaaactc tctctaattt ttatgaattt
    44461 tgtaagaatt acttcaactt cttcaccata agaccatatt tcattaggag ctccagttac
    44521 cattgagcct ccacctttat ttgataatgg tttactatga ggcaatctat ctccatgcat
    44581 tctcaaaatt ggtgaaaaag tagcatattg gaaccatctt accataagtt ctctaaattc
    44641 tgggtcttta ggatttcctc catggaaacc tccaatatca gtagtccacc atggtatacc
    44701 tgccagtccc atatttaacc ctgtatttac ttgattatta aaagcttcaa aactagaatc
    44761 aatgtcacca gaccatacta aagctccata cttttgagct cctgcccaag ctcctcttac
    44821 aagagttaca acagactcta tgtcattatg taaaccatca taaatcattt ttaaataatc
    44881 aataggataa atattaccac aacttaaaac atttcctttt ttatatctat agttatcaaa
    44941 atcatacaca gaatagccag gttcagctac atctaaccaa taatagtcaa tcccaagttg
    45001 tttataattt ttatctattc tatcccaaac atattctctt gcatttttat ttgtcatatc
    45061 tacaaagact gtatttcctt gaatttgcat tgtcattcta acaccacgat taacattgac
    45121 taaataacca ttttctaaat aatcattgta gttttctgca tcactttgaa ctgtaggcca
    45181 tacagatact attggttcta ctgaatactc ttctttcaat tttttaacta attctttagg
    45241 atttttccaa taatctaagt caaatttata ttcaccttgc ttaggccaat gaaaatagtc
    45301 aattgcaatt gatgaaagct taattcctct tttagaatat tccttcacaa catctaaaac
    45361 ttcttctgaa gttctatatc ttagtttact ttgccatagt cctaaaaggt tttcaggcat
    45421 cataggaaca gttccagtaa cttgagaata atttttattt aactcttttg ggctttctcc
    45481 acaagtaatc caataatcta taaaatttgt agaaaacatc ttccattctg tcatattttt
    45541 agcaaaagat acttttccaa ttcccggatt attccataaa agtccataat ctagactaga
    45601 aatataaaaa ggaactgata tttgagaatt tctttgggct aactccaaaa cagtattctt
    45661 taaatctaaa aatttatgtt gatattgtcc cattccaaaa atcttttcag aaggctcaga
    45721 ttcaaatcta gtagttactt caaattctcc actatagctt ggtcgatatt ctcttgattt
    45781 taactttaga gtagagttaa agtctttggt aatctcaatt gtccctacat cttctccacc
    45841 atcatcatgt tttacagctc ttaatcgaat atattctttc aataatattt catttttatc
    45901 attataaaaa gtaattctat ctctatggtc taagacagct tttatctttc catttttaat
    45961 gattacactt ccatcttcat ttttattaat tgtaatatca tctttattta acttaggttt
    46021 ttcgttaaga gcatagtttt catcaacaaa attttggtct acaaacgacc taatacgtaa
    46081 agagtttttt ccccatgctt ctattcgcaa tagttcattg tcaaatcttt tttcaatata
    46141 gtcttcagat atttttatca cggctacctc ctaaatcaat ggtataatat tctatctttg
    46201 tgtagcttaa gttaaataat gtcgtttagt atcgttattt ataaattagg ttttatatat
    46261 aattcatttg tacattaaac taacttacca ataatatact ttatttgact ttgtttgtca
    46321 atcgctttcc ggattttagt aaaattttct aatatattgc tggaaagtca ttcttaatat
    46381 tttttattta tacttttaat atttgtgatg atacctatat acatctagat tttttaaaac
    46441 gcatacagga ataacgttcg cctattatgt aaataatatt ggacttgaaa atatgtatag
    46501 tgaccttata aatacagata ataatatatt agatattgtt caaaacaatg gattttataa
    46561 ttataaataa tttatgaaat tatttaagaa aatatataat tgtataccaa gtcaaaaacg
    46621 acaacaaata aataaaacta aaaaagatgt tgtctcaaaa tatagataaa tttatttttc
    46681 attgctaaaa tgattaaaat atatttgatt taatatattt gatttaatat aaaaaaagag
    46741 tgtctcataa actaaaaagt tcacttttag acactccttt atatatatta tcaattcatt
    46801 tattacctct ctacattttc tttcagctag tagatacatc tttataagta ctaattactc
    46861 cacttaaaaa tggttcaggt actgtccatt agtcatattt ttctgccaaa tataatggtg
    46921 tttcataatg agacaataaa tatttatatc tttacttatc ttctctaagc tcgtcaaatc
    46981 caactatagg tatctctaaa ttatattctt taagtagctt ttctagctct tctataaaaa
    47041 tacctttccc atccaccatt tgtatatcat ttattttatc catcaattca ttgcaaccac
    47101 ttaactcacc aaaccaacgt ttagaactac atgtcttatt ataaccacaa cttggactac
    47161 catctattgc aatgatactt tttatatcat aatcattttt taaatattca tcaaactgcc
    47221 ttacatgagg tattaacatt tgcctacatt gttctctaaa aaacaaattg tcaaactgtt
    47281 cttttacatg tccccaccta tttattccat acataatcat ttctgggcat ggtagttgaa
    47341 ttattccata ccctttattt actaaatcta ttgctatatt ttgtgctccc ttaaattctg
    47401 acaatccctc tactttagaa ttacaattta atatacaatg acatactact acaatctctc
    47461 tatttctctt cataataatc tccttagtta ttcttaattt taatgatact acatattttg
    47521 ataattatat tatttatttg ttctatattt ccaatattct atatagaaat atacaattag
    47581 taatctttta taatctatac tatgataaat gtatatattt tttttaggag gtattataat
    47641 tggatactaa aaaaatcaca ttttcttcaa tgtgcatagt tattaatatt gtcttaggta
    47701 tggttatatc tatgataaat ataccattat tatttttaga tacagttggt actgtacttg
    47761 gggctgtcgt attaggtcct ttttggggtg ctcttattgg tgggtgtaca aacttagttt
    47821 taggtgttat atcaggtcct acaaatatac cttttgccct tgtaaatatt gttcttggtc
    47881 ttattgttgg atatatttct aagaaaaaag gttttggtta taaagaagct attattacag
    47941 gagtaatttt atctattgtt tgtcctttaa ttggtactcc tatttcagtt ttattgtttg
    48001 gtggtttaag tggaagtggt gctgatttat tggttggttt tttagttcag tctggtcaga
    48061 agatatttac tgctgcgttc tttccaagga ttcttagtaa tatagtagac aaacctttgt
    48121 cttgtattat ggtggtatat tttataagta aaatgcctaa aggttttata aaacaatata
    48181 gtaaaaatac ttctagttca tattaataaa tcatttatta tgtaagattt attactcttt
    48241 aaaatgcgat atactcattt ttatataaca tttttattaa taatttaatt agatagtatt
    48301 tgtattattt taattaaacg taacctcttg atataaattt gagctataaa tctatatcaa
    48361 gaggtgctat tttattttta atataattaa tattctatta cgcaaaaaat gcatatattt
    48421 cattatttta tggaaaatat tacttcattt aactctatat caaactcatt aagtaaaaat
    48481 ctaattatat ttaatttagc ctctgtattt aaatttgttt ctaaatatat attttctgat
    48541 attttaatac cttttcttaa tttatatgca tctctagact taatattatc tataaaatcc
    48601 cttttataag ttttgtctac aatactgtta aaccttacag aatccaaatc atataaagta
    48661 agagcaactt gttcataaaa ttctgtccaa tttttagcct tatatgactc tcctaatata
    48721 ctaaatgata ctatactttc atttgtaaaa ttaacatcat catcctctaa cgtaaatata
    48781 ttttcactgt tacttggagg ttcatatgta acacttggat atttccaaat ttctacagct
    48841 ctatctagta atatcttagt tctatttttt atttcttctt cattccattt atctatagat
    48901 gaaatatatt tatttagata aatcctacta tctttaaatc catcttccat ttctttcttt
    48961 tcttcaaatg ttttattact tagttttgaa ttatatcctg tcaaagttaa atttccaatt
    49021 gtatgtaaat atttatcatg tatctcctta tagttatctc ctagtgattc cttccattta
    49081 tttgttaatg tctgtggcat tatatgctct atatttagca tattattatt gattaaattt
    49141 tctaaatcaa caatttcttt attattataa ttctctaacc tctcaagtat atataactta
    49201 ttctttgact tagtattata tatatcttta gtttcaaaag catttgaaaa ttcactgtca
    49261 gtaggaaatc tttgagatga tttcttattt ataaaaatat atcttaatat attagaatag
    49321 ttttctttat aatcactaaa ttttttaatt tcccttccta agttcataaa tactttattc
    49381 agtgcattcg gaggtacatc acatactatt cttcttaata taaaacattc tactaaatta
    49441 agggattcta caagtacttt tttatttatt ataccttcat tataatcatt aaataattct
    49501 aatataaacg gatatgatac aaatatttca agtttgttta tccttttcag aactttgttt
    49561 acatcattat catcagtaca tgaataagat atctctctat aatagttaga aaatttaagt
    49621 aaatctttta ataaaatttc tatatctata ccattatctg atacatacct tttaaaacta
    49681 aaatatactt tatttttatt tggtatactt ctctccttta tagtcaaata gtctcttata
    49741 aagctactta cgttgctact tgtatttttt tcaattttat accaataatt attataaaat
    49801 tcctcttgta acttagagct tctacccatt aacacaaagt ttcttactct atcagcttca
    49861 cttaaatcta agccagttga atttagactt tcaaagatta attgagggtc atcttcacca
    49921 ttttttaact ctatttctac tatagttaat ttctgtatag catcaaacaa atcatctatt
    49981 gatatattat cttcttttat tctattataa aaatataaat aatttgaaac tatattagaa
    50041 tttctatctg tattcatttc ttcttcaaat agttcatagt acgcctttct atcttctgct
    50101 attggtttta actttatttt tccatcttta tctcttgagt gcttgtttat aagataacac
    50161 tccttaatct gttcttctgt tgtaataata ccttttgatt ccccaaactc ttttattatt
    50221 tgacacatgg caatcaataa tattgacaca gtagtcactc tttgttgtcc atctattatt
    50281 aaatattctt ttcccatact atatatagat acaactgacc ctaagaaatg agttctaaat
    50341 ccagaatcta ttatatcctc taaatcatca aacaatcttt tacattgttc tttcttccag
    50401 ttataatttc tttgatatac aggcactaca aaacttttgt ttgacccctc taaataacta
    50461 agaaattcaa tttctcctgc tttcatatta actcccccta taagttaaat aaattccatt
    50521 cataactcca tgtatctata tattatatca aaattttgac tcataaatgt atatgaaagc
    50581 cttattatat acctttttat acctgttttt attttattaa agtaaataca tgattattct
    50641 ataaaatata caaacactta attttaaaaa ttattattta atcttcttca tgagtaattc
    50701 atagttattt atcaattaaa aagagatatt gcataattat tcaatacctc tctttgtata
    50761 tttacattat ccatatctag ttatctattt caacccaata ttagactacc tactaataaa
    50821 tttattctct acataattaa caataatttt gcactaaata acatcattag cctatctctg
    50881 atgcattttc tttaatttta tttatagttt taatcaattt atttctctct tcaatatgat
    50941 tttcaaataa atcaattata cttccaacag ttctaaatgg gtcttccatc aacactttgt
    51001 tatcctctat aaatccattc ttaactacat aatcgactat aagtttaaca aaatgtattt
    51061 gcttagtatt aaaactctta ttatttaaaa actctgaaaa agcttcattt gcagcttctc
    51121 tatccaatcc cactagtttt ctcactaatt gacttactgg agtatctcca aactccttct
    51181 tataatcatc acaattacct aactgcttta agagtatttc ctccaacgtt tcaacatctt
    51241 gctttgttat ctttttatta tttcttaatt taaatattgc taattcatct ttatggctat
    51301 ttaaataata ctctaccttc tttttataat tcttaagatt gtttgcatta tatacagaat
    51361 catttctatc ttctgctaca atcatatctt caaaacttgt ataatatatc ttttgactag
    51421 acttttcaag atacttaata agctctctta atgatatacg tacttcttct acctcaaata
    51481 tatctgaatc ttcccaaaaa tcctctgtca ttgctttttc aatagtatat ttttgttgct
    51541 gaatctgtgg tatagtccca agtttcgaaa gtttttctgc tgtaaccatt acatgcctta
    51601 tccctttact tgcattatta ttttgtaagt atgcaagttg tatattatac ataactacat
    51661 caaatctttt agccaattca tcatcactat atgaagttat gagtggtgat atatattctc
    51721 ttatctcatt ttgtgctact gctccaatat tgctccaaac attttcattt ttatacttat
    51781 gtacataact taaattcatc ctaactatat aactatcctc atttaaagct tttacagaag
    51841 ttataagttc ttctaacaat tcttttctaa gttctgcata cttaccttct atatatttaa
    51901 tatcttgaag ttctttaacc atacttacct ttatattaaa taatttttca gtaagtgttt
    51961 ctgctttatt tccctcaaat cctttaggat taaatttaaa aaattcaaaa ttattacaaa
    52021 aatcaaatat taagaatctt tccttatcca tatcaacacc taataaatct ggacataatc
    52081 tagttcctct acctatcatt tgccaaaact tagtcttact tctcactttc ttaaaaaaaa
    52141 caagatttag tatttcaggt atgtcaattc ctgtatcaag catgtctact gaaactgcta
    52201 tttgaggtaa tttattctta tcagaaaaat catctattat agaatctaca taatttatac
    52261 tatagtcaac tgcttttaca aagttcccac catactttgg atacagttta ttaaatcttt
    52321 caactattgc cctagcatgc tttgtattct ttgcaaaaat tatagtctta ccaatctttt
    52381 cttctccttc tattttcaac ccctctgtca ttagcttatt taaaactaaa tctattgtgt
    52441 cagaattaaa tagccactca tttactgcat tattccctat ttcgtctcca atactctcat
    52501 catcattaaa tgtattttca tattcttcct tctcttcatc agaaagctca tcatacttaa
    52561 ttccatcttc cataatctta gtcttaaact caatactagt ataatctact aaatatccat
    52621 cctcgactgc tttattatac tcataagcat atgtaggtac tccattttcc atgtcaaaaa
    52681 ctgaataagt atttttatct atctcatcct ttggtgtagc agtaagaccc attaagtaag
    52741 aatcaaaata atcaaagatt gacttatact ttttataaat acttctatgc gattcatcta
    52801 ttataattaa atcaaaatga ccaggtgtaa acaatctctt tccatcctta gacttcgtat
    52861 catcaattgc attcatcatt gttggatatg tagaaaatat catcctagca tcttctgggc
    52921 tgtctttgct atccaataaa ttacataacg ccaagttagg taatagctta gtaaaacttt
    52981 ttttagcttg ctttaccaat gcttttctat ctgctagaaa taatatattt ctaatccaat
    53041 tatgtcttga aagtacatca actatagata tagcaattct tgtttttcct gtaccagtag
    53101 cacataccaa aagagttttg cgttgcttat tttcaagagc ctcacataca gccctaatag
    53161 cttctttttg ataatatcta ttggatattt catcatttat tgttacagaa cttaaagact
    53221 tcttactctt tcttctatct atcataagtt gtaattctga ttttttataa aatccataaa
    53281 ctttcctatc tgaatagtca tcccaaatat acatatcaaa accattcgtc aaaaatatta
    53341 ctggtctttg actatatctc ttttccaaac agtctgcata taatttagct tgttgttgac
    53401 caattttggg gtctttgctc gttcttttcg cctcaactac tgctaatggc ttaccatttt
    53461 caccataaag aacataatct acatatccta caccactttc attaggcata ccttgtactt
    53521 ctatttcctc ccctatatct tttccaaatt cccaacctgc aagctttaat tctatattta
    53581 tatatctttt tcttgtctca aattcgctta cttcgtctat cttgaaatca tagtttacag
    53641 tattaacttt tctcttttca gttagtgact ttcttaattc ctcattttct tttattactt
    53701 cttcaagctt tttatctttt gaacttaatc tctcataaag atttttaagt tcgtctggtc
    53761 tcgtcctttt ctcttcccca tgaagtaata aatcttcatt aaagtcttct gctgtatatt
    53821 catctgaata acaatagtct atccaactaa caaattgatg caaattgtta agtgaaagta
    53881 ttgcttctcc tctctctatg ttcgcactag tatgtacaga taaattacct aatttaacta
    53941 tatattttaa taaaggtaac atatcatagt ctataagttc tataaaacta ttattatgaa
    54001 tcaacgtact aagattatct tgataaggca atactaaatc actatcatta gcatatagcc
    54061 attttactgc aagctctaaa gctcttcttg ttatagttgc acaagtagat gggctaacta
    54121 gtatactttt ttctgcttct aagcaagcag tattaaaact attgaaattt ttcttctttt
    54181 gtaaaaagtc aaaattaccc aaggcttttc tccccctttt gtcccttagt taaaataaat
    54241 ctctctaaaa actatttctt acagctgttt cttatactaa caaatacttc ttcattttct
    54301 gtaaacaatt cgtacatatc ttcaaactgt ggtatatcat atccatgaga atcatcattt
    54361 ctcaattttc taagtgtttc tataactata gaagaatttt taggtaataa attgtgatac
    54421 tcacaagcta aaaggtagtc ataaaagttt ttagatttta tgtttaaatc aattgattta
    54481 taatacaaca ttgcttttgt taattctaaa aatgatacca tatagctttt aaaaccttct
    54541 tttatatatc tagcccataa ctcaggcatt tcttccttat catataagat tttgaagttt
    54601 tgcaggtcat ataagcaaga accaaaatcc ctatttactt cttctattga gttccaagat
    54661 aatttgtttc taattaccat acatgtccct ccaatctaag atatctatta catcactgtt
    54721 ttcaaaatag aatttattta tataatcctt aaaatcttta gattcataaa taacttcacc
    54781 ttctaaaata gcttttttaa gtgctattgt ataattatct gtaacaattt ttaggtctac
    54841 atcaatgtct aatatatttc ttagagcttc tgtcttagtt gcaagttctg taattggtac
    54901 ttttttgata ggaatccaag ctatgtctat atcgctttct gatgtatgtt tatctgttcc
    54961 ataactacca aatattatga ttgctagagt attttctttt ggaaatacat ttattattga
    55021 gtttttaatc tcatttggta tatttctcat ttaatcacct cttgtttatt aggtaatatt
    55081 gcttaattga atttatatcc ataatctttt aatctattta tacatatttc tctttcttca
    55141 tcagtaaaca actctttata cttttctttt aatactaata cttctaatga taaatctaat
    55201 ctcttacact cccatagcct tgtaaatcct tcagtagctc cttctttatt gattaattct
    55261 ttagcagcta ataaggctcc tttgttattt atcagttgta aaaatcttgt tggcttatag
    55321 ttacattgta aatcagcttc tttatagata tttaccatgt catggtataa atctagctct
    55381 atttgattca tagattttat tcccccattt taataattgt attttagttg aataattctc
    55441 ctttaaaagc tttttgcatt aatgagttaa agttatcttc taattctttt aggctatctt
    55501 ctatttttaa ttttaattta tctacttctt taataaaccc aacaaattca ttttgaagtt
    55561 ctactggtgg taatattata ggaaattctt ctaaatgttc tttgtttatc tgccttttgt
    55621 caataccccc aacacataca cttcttatat attctctata tacatctatt gtaagtataa
    55681 ataaaacaaa ttcatttata atattctttt taagtcttat aagataaaca tgtccattaa
    55741 tattagcact atcatcttct cccaaaaaca tagctgctct acctaaacta ctattttcag
    55801 tatttattct tccagtttta gttattaaaa tatctctatt tttcaagcta ctttttttca
    55861 tactattatg agtttcttca tcaatatatg ctacatcatc aagtactaat ttatttttcc
    55921 aaacattttg acttcttaaa aagataattc ctttttcaat ataaacctga cttcctccct
    55981 ttggggtagt tccactcaat atttctgttg atatatcatt taatctttta aattcccatc
    56041 ctctagggtt atttactgga ttaccaaaca tctcaataaa tcttgattta actaattcat
    56101 ccaatgcttc tatttgctct tttcttttat ctattaactc ttgagcttta tctaaaacct
    56161 tcactatctg ctcttgagtt ctaacatcac aatatggaat ttctaagttc aatatatctt
    56221 cttttccaat atttatttgt aaccctccac tagcaaattt cttaaaataa tttttattct
    56281 gtggtagact taatgtatat tttaaatatg actctagaac tttactttta tctaatagta
    56341 taagctttcc tactctttga ttaagcaaca ttttataccc tttagtatca actatggtag
    56401 gaactcctaa taatttaggg tcattagcta aatcagtcat tgctattatt aaatctccat
    56461 ctttaagtaa gtactcctta tatttttcag aaaaatcttc tggtaaatat tttggattat
    56521 actctgcatc aaaattagca ttaggtctaa tattactcat tctacaattt aaaacgttag
    56581 aagcttcaat ataatcactt gatttgaatg caaaaccatt cttaagatca caaacttctc
    56641 ttaacttaat atattccata ctctacacct ctaacattct ttctagttcc tctaatccat
    56701 ccactatctc tttctctaac tccctaactc tacctataat cacactagga gcatcataaa
    56761 ctacttcctc atacactacc tctttatact tattaataga taaatcatac ccattctctc
    56821 ttatctcttc cacatcaaca aaaaagcttt gctctgttct ttttctatct acttcaccat
    56881 caagattatc aaatctctta ataatatcct ctatatcact atcctttatc tcatttctct
    56941 tatcatccaa agaataacca tcagctttca tatcatagaa ccatacctta tcagttccac
    57001 ctgtccctgt tttagtaaat atcattatag ctgtagatac tcctgcatat ggcttaaata
    57061 caccacttgg cattgatatt atagattcca atttatgatt atcaactatt tcttttctta
    57121 ttgatttatg tccacctgtt gaaccaaaca atactccatc tggcactata catgcacatc
    57181 ttccaccaat ttttaaaact cttaaaaaaa gtgccaagaa taataactct gttttctttg
    57241 tcttagtcac ttttaataag tctgctgaca ctgcttcata atctaaactt cccttaaaag
    57301 gaggatttgc taacaccaat gtaaacttat ctttatctgt attaacctcc gataaagaat
    57361 ccttatactc tatattagga ttgtcaacgc catgcaacat catattcata gcacctattc
    57421 taagcatagt tctatccata tcaaatccat agaacatacc attattaaaa tgctccttca
    57481 gcccttgcac taagaaaaga cttgaatgat tatcccttaa gtactgttgt gatgatacta
    57541 aaaaacctgc cgaacctgct gccgggtcta ctataatatc ttctggtgtt ggtttaataa
    57601 gtcttactat catatctatt atgtgtcttg gagtcctaaa ttgaccatta gtacctgctg
    57661 tagccacttt ggataataaa tactcataca aatctccctt tgtatctcta tccttactta
    57721 attctaaatt actaatacca tcaactattt tagataacat aagaggcgta ggaattttaa
    57781 atattgcatc tcccatgtac tttgcataag ctgattcttt atttccatgt aattttttta
    57841 tgaaaggaaa cacttcattt tgtactattt catacatttt ttctgaattt ccttcattag
    57901 aaaacttact ccatcttaaa tgttgatgtt catcatcaaa tatcttttca aaagaaacac
    57961 ccaaaagagt tgcttctgct tcattttttg tttctacttc atccaatcct ttaataaata
    58021 aaagatatgt aaattgttct ataacttcta atggattagt taatccacca gtccaaaatg
    58081 tctcccaaat cttatccact ttactcctta attctcctgt aatcatatat gactttccct
    58141 ccagtgttca taaaataatt taaatatata ttttagtcgt acgccttaat agttagtgtc
    58201 ttatgttaaa tccaagtttt tactacacaa ttattaaatt atttttccta tttacatatt
    58261 ttagctaaaa aactaatgca atactcttat tttatgatta ttatatatac catacaaaat
    58321 tattttatca tatatccatc atagaagtca tctacctgga taactcttac catattataa
    58381 ctttttaata ttaatttaaa cttagaaaga aattttttat ttaattatat catcttcctt
    58441 atttcaaatt tctcaactac aatcctaatc aaaaaataaa ataagatgct gtctcaaaat
    58501 agatataatc ttctttttta ttgtcagaat gatgaaaata tatttgattt cacacaaaaa
    58561 agagtgcctc atgaactaaa aagttcattt tgagacaccc cttaatttaa tcttacttat
    58621 tctttccctt tattattaac acttcactgt ccctattgct tttcctacac atccacaaac
    58681 ttccatccta ctcttaacaa aatctttaac tgactctaaa ccttttttac catatttctt
    58741 agggtcaatt acctctgggt cagaattaaa cacatcctta accccattgc tataagcaat
    58801 ccttaattca gttgcataat taaccttgca aatacctctt tttatagatt ccttaataac
    58861 ctcatctggt attccagacc caccatgtaa tactaatgga actgatacaa cctctctaat
    58921 ttcagataat ctatctaaat caagctttgg ctctccctta tataatccat gtgccgtacc
    58981 tattgctact gctaaagatg atacccctgt tctctctaca aactcttttg cttctaatgg
    59041 gtctgtatat gctcccccat caccaccatc taaatcgtct tccttacctc caactttgcc
    59101 taattcagcc tcaacaggta tatctgaagg catacatgca tctacaacag atttagatat
    59161 tgaaatatta tcttcgtaac tttcatgaga accatcaatc ataatagaag tatatccaac
    59221 tctaagtgcc tgcatagcta gtccaaagct tgaaccatgg tctaagtgca ttgccactgg
    59281 aacacttgcc ttctctgatg ctacctttac attcgctaaa taataatcta gtcctgcata
    59341 ctttattgtt gaaggtgttg tttgcaatat tactggtgat ttaagttctt cagcagcctc
    59401 tattactgcc ataaccatct ccatattttc aacattaaat gcacctactg cataatgccc
    59461 ttcttgtgca tctaataata tttgtttagt tgtcactaat gccataattt ctcctcctat
    59521 atgtttatac tgatttgatt tcttcgttat ttaattttga tactatttct ctacttgttt
    59581 tgctatttaa taactcattt aaaaattctt cattcattaa ttttgaagat agttgagata
    59641 atgtttttaa gtgtaaatta tcaccattat ctgtagctgc tatcataaat ataatatgtg
    59701 ccaagcttcc atcttctgat tcaaagtcaa acccttcttt tgatacacct actgctacac
    59761 gtggtacctt tactgcatct gtttttgcat gtggtatcgc tatccccata ccaaaacctg
    59821 tagatgatat ttcttctctt ttaaggattt cttctttaaa cttcttttta tctaaaagaa
    59881 caccagattt atcaagtatt ccaatcattt catcaattac atctgtttta ttttttccct
    59941 taacatctaa aattactgtt tcttcgctat ataaagagat attattagat acgttttccg
    60001 attctgcact ttcattttta tgtccatctt ttgttgcatt tgtattttct atagtatttt
    60061 tctcatttac tactttaggt gtaaccatca tataaagtac agcacctact aatgaaccta
    60121 caaatataca ccctacccat aaaagtggct tattgactaa tcctagaact aaaaaccctc
    60181 catgtggagc tggtacttct attttcatta tataagttaa aattgatgat attgatgatg
    60241 caatcataag tactggcaac acttttaatg gattttttgc tgcaaaaggt attgccccct
    60301 ctgttatatg agtactacct agtatataat tgattaatcc tgctgctcta tcttcttctg
    60361 taaatctatt tttaaataaa gtagatgcta ttgctattac caatggtggt gttatacaag
    60421 ctgcagatac acctgccata aataaataat ttccctgtcc tagaagcata gttccagtta
    60481 catatgctgc tttatttact ggacctccca tatcaaatgc tgacatacat cctattacta
    60541 ttcccaaaat tatagggctt gaattttgta accccgatag aaagttcatc atagcattgt
    60601 taagtgctga acatggccca ccaagtaaca acattgctac acccacaaga cctacgctga
    60661 caataggaat tataaaaatc gatttaagac cttctaattg tcgtggtaat tttcttaaca
    60721 aatgtacaaa tagtttaact aagtaacctg ctaaaaatcc tgatatgatt ccacctaaaa
    60781 accccgaacc tgtatcaaat gatatcattc ctccaacaag tcctgccaac ataccagctc
    60841 ttcccgatat agattgagct ataaatgctg ccaatacagg aaccatcaag ttcatagaat
    60901 atccaccaac agattttaat gtagctgcta tttgattata ttgttctgaa tttgggtcaa
    60961 atgaataaat cccccataaa aatgatatag cagtaagtac tccacctgct actactaaag
    61021 gtaacatgtg agatacacca ttcattaagt ctttatacaa cttttgacca aacgataaat
    61081 ttccttcttc tgcaatttta ctgcttgata agtttccttt tctaatagct acttttccat
    61141 caatacacct ttgtataagt tcattagcct tatgtatacc ttctttgaca ggtacttcta
    61201 ttaccggctt tccattgaat ctgtccatat caacattttt atcacaagca actattattg
    61261 catctgccat ttcgatatct tttgctgtta acttattttc tacacctata gctccattcg
    61321 tttcaacttt tatgtcacac cctaattccc ttgctgaatt ttttaatgct tcttctgcca
    61381 taaaagtatg agctattcca gttggacaac ctgttacccc tagaatcatt ttctttccca
    61441 tctttatacc acctttctga ctcttatatt ttttatataa ttttccacat tctccaaatt
    61501 acctatacca ttactttcag ccacacttgc tcctgttgct gctgaccttt ttaatgcttc
    61561 ttcaatatgt tctggatttt ccaaccatat acttaaaaaa gcagctaatg cagaatcacc
    61621 agcacatgca gagctgacta ctgtaactgg ttgagcacta gcataataaa ttgattttcc
    61681 attataaaaa taagaacctt tttctcctaa agttagcaat atattttgag caccttttaa
    61741 atgcagtaat ttaagtacat ccttaatatc ttcttcatct cttacaataa ttccaaatat
    61801 atctttgatt tcttcatcat ttggttttat caaatatgga ttatactgta gtaactcctt
    61861 taattttggt gaacttatat cgagtattgt ctttatactt ttatttttac aaattttaaa
    61921 tatatcctca tagtaattat catcaatacc aggaggtaga cttccactta ttgataagta
    61981 acttatatct gctaatgact gtatcttatc tagcatatct agtttttgtt tttcgtttac
    62041 atatgaccca gagtttacaa atttaaattc atcacttcca tcatttaaaa atatatttat
    62101 acgagttgta tcttctaccc aagtaggtaa tacgtcaaat cctctctttt cgctttcttc
    62161 aactatatat tttcctgaaa atcctccaaa aaatcctaat atcttagatt ctataccata
    62221 atgacctagt acaaaagtta catttaatcc ctttccatta ggagaatata cagcatttga
    62281 tgtacgattt actaattttc tctttatccc attagtagat atattcatat ctattgcagg
    62341 attcgtagtt aatgtatata tcattgtctt cccccttgct tgtgctgtgt atgttttcat
    62401 tataataaaa aagtctatga aaatcttttc acaaatagaa aatcgatttt catagacttt
    62461 tcaatttaat tttcagaatt attatatctg accatataat ctataattat cctagatata
    62521 atatacaagg gcaatctgga agatacttca tattcagaaa ttgatatatg ttcatgtttg
    62581 tatcctacaa tatataaatc cgaatacttt ataagttttg cactttcact acaacagcaa
    62641 gttataacct tagctccaac taaattggca ttctgtgctg attctacaag ctctatggta
    62701 tttccattca atgaaaatat gattataagt tcgtcttttt ttattgattt agattttatt
    62761 ttcattatgt tggggtcatt tataaaaaca acattaaaat caagtaattg caatttaaga
    62821 ctaaactctt ttgctacata ttcagtaagc cctcttgcca aaatatatat cttactagat
    62881 ttatttatag tttttattat attgattagt gtagttaaag atatttgttc tataactctc
    62941 tgtgcttcta taaaggattt atttattata tcccccatat tttgtatatc atcattttca
    63001 tcttttactg ttaatctata cctaagttca ttgaatccat ttaaaccaca ttttctaatt
    63061 gctcttgaaa cggttgctgg agatgaatat gtttcatgag caatctctac tatagataat
    63121 tctggtaata ttgattcatt ttcatttata aatttaatta tttcaagttc cgtcttcgtt
    63181 agattttcag aattactttt gtttagctca attatcatat gttatctccc cttatataag
    63241 ttttatttgt ctaaatttat cgagtaatat aatatattac ctcttaacta cttattttta
    63301 tatacaatta agatttagtc aatgtctata tatgtaaatt tataatataa taattttatg
    63361 cttcaatcaa ttatgtaatt attagagtat tttgtaataa aaattggagt tactcaatta
    63421 ctgaaactga gtaactccaa ttcttacaac ctcaaattaa ctcgaattat tgaaaatgat
    63481 tcataaacat tatcctatac tctcacttat caatttatat acttgagtaa tacctttttt
    63541 tattaacaga aatcatctta ctaacaattg aaattgtagt tccagtacat aatattgaaa
    63601 atacagttcc aaaccctaaa tttccgccta aatatacacc taaaattaaa aatattaaat
    63661 ctgctatagt ttttaaaact ttatatggat acttaaattt gccctcaata tagattaata
    63721 tagcatctaa agggctcatt ccaatgtcaa attttataag cattgcaaat ccactacaca
    63781 taagtatatg tccaattata aagctcatta ttctaatgat aatccctaaa ctacttatat
    63841 taaaatctaa taataagtat atatacaaat ctataaatat tcctgctact aatacataaa
    63901 cacagcttcc taatcccaaa ctttttttat tcaatagcaa tgctataagt aatagagttc
    63961 cattatatat tagccctgct attgtataac ttatacctaa ctttatatgt ataccctcat
    64021 ttaaaagtgt aattgcatca ctaccaaggc ttgactgaag tataagagat ataccacatc
    64081 ccagtatatt tataattaaa attacaaata taaatttttt tatgacattc ataattaata
    64141 aaccacctta tttataatta taatccctct tataaaactg tattaataac atagtattta
    64201 taagagggat tatttatatt taaaaactat ctactttttc ttttaattct tctccattag
    64261 ttcttattac atttttatac caataaaaac tatctttttt gtaacgttct ttgcttccat
    64321 ttccattgtt atctatatct acatatataa atccatatct tttttccatt tcttgagatg
    64381 aacaacttac tatatctatt ggcgaccaca tacaataagc taatatttcg gttccatcag
    64441 ctatagcttc acctatttgt tctatatgtt ttcctaaata atctattcta taactatcat
    64501 gaacttttcc atcttcaaat ttatcatgca ttccaaatcc attttcagct atcattattg
    64561 gcttttgata tctatcataa tattgagata aagtattgta taatccttta gggtcaattg
    64621 cccaccccca aggatttgct tttaagtatt gattttttac attatcaatt ggattcatgg
    64681 tatttttact tgctgatact gttgtagagt aatagtatga tagagctaga aaatccatag
    64741 tattctcttt taacacttta tcatcacctt cttccataac tatatttatg ttattttctt
    64801 tgaagaatct cttaatataa gctggatact cccctctaaa acttacatca gtaaaaaaat
    64861 attgtattct atttcttttt aaagcaaata ctacattttc agggtcgcaa tcttctggat
    64921 aagatgtaca atctgccatc atcatcccta tcatcatatc tgaatttatt tcttttccaa
    64981 gcttcttagt taaagctgta gccatgaatt gatgatgaat agcttgatat ttggcctctt
    65041 ctacatcatc tacctggtct acacaaaatg caactgaatt aaatgattca tgatacatta
    65101 aatttatttg gtttataact atccaatatt taactttatc tttgtatcta tttaatatta
    65161 attctgcata tctaacaaag aaatccacta cttttctatt agaccatcct ttatatttta
    65221 atactaaatt caaaggagtc tcataatgga gtagtgttac aataggttcc ataccattat
    65281 ctattacttc atttataaga ttatcataaa actttaatcc ctcttcatta ggctctaaat
    65341 catctccatt tggaaatatt ctagcccaat ttattgaaaa tctaaaacac tttaacccta
    65401 gttctttcaa aagctttaaa tcttctttgt atgtatgata aaagtctatt ccattacgct
    65461 taggataata cccattatta tctttcatag caaactttat tttatctaca gtcatatcag
    65521 actcgtaatg tttagatata tctctatctt tatcatacat atgtacatca gctaagcacc
    65581 accctttgcc accttcattc caagcacctt ctaattgatt agctgctaca gctccacccc
    65641 acaaaaaatc tttaggaaac ttactcaatt taatcactcc ttattttatt tatttaaatc
    65701 atttactatt atttacctta tattctatag actttactat tcctactaaa gacatagtta
    65761 tatttaactc gctgaatatt gtcataagag tatcttgagc atgtgcaaat aaaagtgaat
    65821 gtgctctttt ttctccacta gcttcccctt gtataatgtt agtttgagct ctatgtgctt
    65881 ctgtcataaa ctcttttgct ttagctagtt ttaaatcagc atttttataa tcaaaccttt
    65941 ctaaatcatt aagagcatgt ttaatttctg ttctagcctc acctgcacga agtattattt
    66001 gcattgctac ttctactaat tcttcatcta ttacatgttc ttcagttgtc atatttataa
    66061 tttcctttca acatctaaat ttaagcttct tgactctcta attttagttc ttctttttca
    66121 taagctttaa aaaatggata ccatatcatg aatagcaata ctatatttat tgctaaaaca
    66181 ataagccctc taacatcttg atttaccata aaagtagata taccaaaagg aacataccat
    66241 aaattaaaca ccttactcgg aattgtcaca aatcccatac tcattgataa gtaagtagtt
    66301 attgatatta ctactgttcc tatccacata ggtaacatta aaaatgggtt ccatgctact
    66361 ggagctccaa acattactgg ttcatttatg ttcattatag aaggaacgat acaggctctt
    66421 ccgattgctt ttattcttcc agctctagat aaacacatca ttagcactag tggtaatgtt
    66481 gctccccacc cacctaaagt tatccaacct gtttgaacaa cttcataagt atatatatta
    66541 gttgcaagcc ctcctgatgc tacagctgct gcattagctg caattgcact aagctgaatt
    66601 gcataagtta ttggggataa tacccatcca cttataccta aagaatataa aaatactact
    66661 aagaagttta atagtacaaa tccaggcaat gtttgtgcta tatctgatac tggtttaaat
    66721 atcctaacta ttatttcaaa catatcaaag ttaagtccat aaattagtcc ccaacctata
    66781 aacattatta ctgctatagg taacatacta tcaaaccact tacttacaaa atcaggaagt
    66841 gctgaatctt caccaaaaaa tgagaaagac ccaaataaag acattattaa tccggagaat
    66901 aatcctgcaa ctagtgctac aagcattcct tctcctccaa atctattgaa gttaaatata
    66961 gctccttcat tcgtaatctc tggacgaatc atcattaaca ttaatccagc acctgcaaga
    67021 ccagctacta cactcatact ttcaaatttc ttattcttca ttatttccat aggtaataaa
    67081 aatgctataa atagtcctaa aagtccaaat gtatattgat ttattggact taaatcaggt
    67141 aagaaactta tgtaattctt caagacagaa actatagtta ctaaagaacc tacaaatacc
    67201 ataggcaaaa ctttcattat agttgattga actgattgta cccatatatt cttagttatc
    67261 ttatttacaa caggagtaaa cttttcactt aacaaatcta taaatttatt cataaacaat
    67321 ctccccatag atattttatt tgtttaatat taattctaat gcttcttcta aagcctttac
    67381 accatctaat cttccatatg ctgttttaga tatacatgct actggaacat tatattcatc
    67441 agcttttttt tgtatttcat ctttcatata atctaaatgt ggtcctaata ataaacaatc
    67501 tatttctggt aaatatttat ctatctctga ctcacttcta gcttttatat ctgcttctat
    67561 gccttttttc tttgcactct ttctcatact agttgccata aaacctgtac ttgctcctga
    67621 gccacatgcc aacaacactt ttatattctt cataacaata cctccagtat ttttatccat
    67681 taatttattt cttaatgaat ttttatttga tttgattgta tttatattgt acttcctaaa
    67741 taatttcctt tcacataaat atatttccta ataataggaa atcatttact cttaaccaga
    67801 cacataaata tatagtataa tgtacattat aatacgtaca ttcaattata taaatatcat
    67861 atcatacaga ttttatttta aaactatgag agggaatcta atgaaaacat ctaaaaaaga
    67921 gttattttta aacttcataa aaacgcaaca tgattggata gattcatcca cattagctaa
    67981 ttatcttaat gtatcaacac gttcgattag aaaatatgta aatgaaatta attctactgg
    68041 tgaatttata ttatcctcta aaaaaggata taaagtaaat ctcaataata actgtcaaac
    68101 caaggttgat agttcagaaa atatatcacc tgataacagg ttaaatttaa ttttaaaaga
    68161 acttatagtt aatagtaatg gaattaatat atttgattta agtgaagaat tgtttgttag
    68221 tccagctact attgaagggg atatagtcaa agctaataaa tttataggaa gttataattt
    68281 aaagataaag caatcgaaat ttttattgaa actaattgga aatgagtctg caaagcgcaa
    68341 attaatgagc tctataatat ttaaagaaac gggaagtgat tttttaagct tatttgatgt
    68401 acaaaaaata tatcaagagt ataatttgac caaactgaaa gaaaatataa tatatatatt
    68461 aaaaaaatac aatttgttta taaatgagta cgctataaat aacatacttc ttcatttaat
    68521 gataactata gacagaataa aaaagaataa ctacatagaa tctgtcgaag tagtaaacta
    68581 catagataat aataatgata taagcatttc aagagatata tcaaattttt tagagtctga
    68641 atacaattta actttaacta gtgcagaatt atactactta gtatttcagt taacaaacaa
    68701 aaccacagtc ttaaattatc atgaaatgga tactaagtca ttgccaaatt atatagatga
    68761 acattttgtt aaattaacta aaaaaataat taaaaatgta tatgacttat actttataga
    68821 tttatctgat gatgaatttg ttgtaaaatt tactcttcat gtaaaaaatt taatcagtag
    68881 ggctaaaaat aatcaagttt tgagaaatca aatacctcag aagttaaaag attcctaccc
    68941 tctgatatat gatatatctg tttatatttg taatcaaatt caaattttag aaaacataga
    69001 aatagatgaa gatgaaatat cgtatatatc tcttcatgta ggttcatttt ttgatagaca
    69061 aaaattacta gaagataaaa ttctctgtgc attaattact ccaaattact atgatttaca
    69121 attcaaaata gtaagagacc tcgagaagag atttaatgaa tccatagaaa ttattcagat
    69181 tttttcagat actcataatc ttgattttga caataaggta gacatggtta ttactacttt
    69241 accaattagt gatagatgcc ctataccttt tgtttatgta aatccttacc taaacagaaa
    69301 agattatgat aatatccaaa gtaaatttat tcagattaaa gatagaaaaa atatacttac
    69361 tgtacaaaat catttagaaa tgtactttag tgaatctttg tttatgaaaa acatatattt
    69421 agatagtgct aaagattaca taaaatttat gggaaatatt ctgtacaaaa ataaatatgt
    69481 caaacccaat tatatagatg atgttcttat aagagaaaaa atgtcttcaa ctgcatttaa
    69541 taacaatgta gcaattcctc atagcatgaa aatggatgct ttaaaaactg gagtatgttt
    69601 aattgttaac gataaaccag ttaaatgggg tgaggaaaaa gttcaaatta tagctatgat
    69661 acctataaat gaaaaagaaa aagaaaaatt caattacata tttgaaagct ttattgaaat
    69721 attatctgag tggaataatg ttaaagaact tactaaggca gataactaca gtagttttat
    69781 gaatagaata gcttatctta ttcaaaatat ctaaatccat taatttattt ccaatatatg
    69841 tttcttaagt tattaacaca aaatagataa gctgtcacac taaaaagtct aaattaatat
    69901 gtgacagctt tttacctaat atactttgct ttaatactac atattttttg attgttgtat
    69961 actagttata agattgaata tttgtgttgt tgtagctgtc atattctcac tagcagttgc
    70021 tttatccatt gcttcttcta ttgtcatagc tctatttact atagaaaaat aagcatctat
    70081 accctcttca ttacatttaa ctgcatcttc tgttgtggct ccagccaaac ctattacttt
    70141 taccccatat ttttttgcca gttttgcaac tcctattgga gccttgccca tagcagtttg
    70201 attgtccaat ctaccttcac cagttatgac aaaatctgca tcttttaact cttcctctaa
    70261 tttaatttct tctaatatta tttttattcc agattctaat tttgaattta aaaatgctaa
    70321 aaaagcaaaa cctaatcctc ctgctgctcc tgctccttct acattagcta catctttact
    70381 taagtaattt ttaactactt tggaaaaatt tctaagccca ttatctaact cctcaattat
    70441 ttctgatgtt gcaccttttt gagacccata tatgtatgca gctccatttt tcccaaacag
    70501 cggattattt acatcacagg ctattttaaa cttacattca tctaattcct ttaatctatt
    70561 ttctattttt atatgtctta tttcatttaa aacttttcca cctaatccta ctaacttgtt
    70621 attttcatca taaaactcaa accctaaggc ttgaagcata cctatcccag catcattagt
    70681 agcacttcca cctattccaa ctataaaatt tctatagcct ttatttattg cttcctttat
    70741 tatttcccca acaccataag ttgtagtgta taaaggattt ctaagttcag tcggaaccaa
    70801 tgttaatcct gatgcttgag ctatttctat tattgctgta cttgtatttt ttaataatcc
    70861 atatgttgca tccacttttt tagctattgg tccagtaact tctatagtct cttttttacc
    70921 attcatccct tgaactaaag catctactgt cccttcacca ccatcagcaa gtggcaatat
    70981 ctttacttgc gcatcttctt taaccttcaa tatccccttt tttattgcat ttcctgcctc
    71041 tattgaagat aagcttcctt tcaaagaatc tatagaaatt aatattttca tatttatcta
    71101 ctccttttta tttactcttt attttaaata tataatttta taagcttaat ttatctttta
    71161 ttttatactc tatatttcac tttgtataca acttatacca ttaatattct tttatcttat
    71221 aaaaaaggga gtgtctcaaa atgaacttta gttcatgaga cactcttttt gtataaaatc
    71281 aaatatatgt ttattatttc aacaatgata aggaggatta tctctatttt aagacaattc
    71341 ctttttagca ctatctaatc atttttagca ctatttaatc agtatagttt taacttggtt
    71401 cattaagcac tctacattta cagagttatt atctattgat atagattcta attctttttc
    71461 atttaggtta atccatttag ctgttttaat atttttgtta aatactatgt tagctgattt
    71521 tgtttcttct ttagaattat aaaatctaac tactaatgcc tcttgttttt cagccttttt
    71581 tacaacactt aacacaaggt ccttattagt ttccttaagt aaactatatg aataatctac
    71641 ttctatttct gattgattca atttcatagc attatatggc attttattat aagtttgtat
    71701 ttttgttaaa tactctttag ccatatttgc aacatttgct tctagtgtag atttttcatg
    71761 agtaactatt gctaagtcta tttttatatc tcctatcatt tgagaatctg gagtaggcaa
    71821 ctttattcct gatggacgac ctgggcgtct tgccatttct tctttaccta ggaatcctac
    71881 acttctaaat aatgttatag ctattgtgtc aaattttttc cctactattt caaactctct
    71941 tgtactgttt gtaagaacag ctactccatg ctctttgtca gacaatccaa cgaatgttag
    72001 cattggatat atagaatctg gtctttcact ccattcttcc tgttgccaaa cttccatagc
    72061 atcatcatac acacttctct ttatatgtcc aaactgatta tcagacacag aaaactttga
    72121 agctatattt gttggtatat aagttctaac cctacaatct cttgcttggt tatttatgtt
    72181 gaatactaca tctattatag ctttatcatt tggaacattt ataactatat caaagtcaat
    72241 aaatgaatct actctattat tttttctagc ttgtatatct tttggtactt ttaatctata
    72301 atttatcttt atctcattat taaatctatt tttctttata gtgtgatttg ctaatatatt
    72361 atcgttaaat attaatttct catttggaag tggtgaaaaa tcatactcat ctccttcatc
    72421 tcctccattt tccatcaata atacattttc aaaagtttta tttaattttt tatcaaatat
    72481 ctttaatgtc ccgttttcat taacttgaat agtataaaag tcattatcta ccatgtcaca
    72541 tacttcataa gctttttcta acatatgttc aacttctttt atcatatacg ccttataccc
    72601 cattgcaggt attttatctt taaagtttat tgtatatacc ataaatgaat catagtttcc
    72661 ataatgaaca atttgacggt ctattaatcc tgcatctatt tcttctttat gtaccacttc
    72721 aaaatccaaa ttattattat ctctatcaaa tatttcaaat gctttcattt tagttataac
    72781 ttgggcgctt actatttcat tcctatcgta aggcattaag ttaaatgcta ctaacttatc
    72841 taaagccatt tcacaactca ttgcatcaac tattcttctt ttgtaaaatg ttattaattg
    72901 gtctactttt tcctcagcta agaaaaatct attcattatt tcctggtgaa ctttatctga
    72961 acaacaacat ccaatgctgt catgagcatg atttttcatt atttctttcc aaattaactc
    73021 tattaatcca tgatgatatt caaatcctag agaatatgca atagaagcta gtggctccaa
    73081 tatgttggtt atctttgatt ctattctagc atttgctgat tttatatcca ttcttgttga
    73141 gaatatactt ctatgaaccc tcatatattt cccatctaaa aattcccctt ttattgtatc
    73201 tatatcctca tttttttcta gctctttaaa tatgttttca tatctactta agaaaaattt
    73261 tctctctgga taacattctt ttaatttata tataacttca aatatattct tttgaattgg
    73321 catttggtcg tgtccatttg gaagtattat atggtcagta gttgcaccct tatcaagaac
    73381 cagcaaatat ttatccattc ttgttcttag ctcatcttca ttcattggta gatattttcc
    73441 tattgcataa cctaatggaa gtatttgaac caaaacagaa gacccatcat cactcttcca
    73501 attaaactct gttttattag ttccttttct ttcagaacat cctctccaaa acattgagta
    73561 ttttatatca aacccattta gtatttgtgg catttgagca ctttgaccaa atgaatctgg
    73621 caaatatcct attttcatat attctccaaa ttcatcacaa tcttttattc catacagtaa
    73681 atttctaagt atggattctc caccaactac catttcatca gtttgagtat accaaggacc
    73741 tattattagc cttccttctt gaactaattt ttttattctc tccttacatt caggcttaac
    73801 tgctaaataa tcttctaata tagcagtttg accatccatc acataatatg gatagttatg
    73861 attattttct aacatatcca ttatttcttc catattattt acaagtaata ttctagattc
    73921 ctcagttgag aagtaccatt ctctatccca atgcatatga ggaactatgt gtacattttt
    73981 tttcattgct tatcctccaa aacttatctg ataatatttt ctgtctaatt aaaaatccaa
    74041 taaaaatact actgagttta cacaattttt taatatttat tttatcacta taattaaacc
    74101 tttgatttaa acatctaata acgtatcttt taatgtatct ttctttgatt tttttgtttc
    74161 ctagttatta ttaataatat tgctgatatt atagctccaa gtactgccgc aaagaaccat
    74221 attgatgcta taataaatcc tgacatactt ccctctaaaa gcgccaatga gaatatcccc
    74281 gctccaggca cttgaagacc tatattgaag aatgctacta tagacccagt tatggctgaa
    74341 ccagctacta atgatgatat aacacggatt gggtcctcta tcataaatgg tattgcacct
    74401 tcagttattc cagccaatcc taatatccaa gtttgctttc ctatttcctt ttctgattct
    74461 gaaaataaat ctctgcctaa aacagtagct attgtaactc caaaagctga aaccatctta
    74521 actgatgcaa atattgcata aggtataaaa tttccacttg ctattgctcc tattgcaaat
    74581 gtataggctg ctttatttat tggtccacct aagtcaaatg aaaccatagc tcctattatt
    74641 gcacctagta gtattgcatt tattccagtc atcccattta accaatttat aagaccattg
    74701 ttaagtgctg ctacaggctt tcctattaca aataacatca ataaacctac taccaaagaa
    74761 ccaactactg gatataccca aaaacttacg aatccagcta atgtgccttt ggctggtata
    74821 ttcttcttta aaaattttac tatataacca gcaagtaaac ctcctaacat acctccaaga
    74881 aatccactac ctattaaatc agctgctaga cctgctgcaa atcctggtcc aagacctggt
    74941 ttttcagcta gtgagtaaga catatatgct gataatactg gaaccatcaa tgtacctaac
    75001 atccctccag aaagctttct taattgccat aaccaagaac cttcttgatt gtatagttct
    75061 tgtaaaccaa atgcttgaga tgctaatact gcaaatgcaa gtatcatacc tcctgccaca
    75121 ataagtggta ttatatgaga tactcctgta agtattgctg attttacatc ttttttccat
    75181 gatgattttt cacaatatga tatatcagat gatttttcta tataatcacc tttaccttgt
    75241 ttttgtgcta cttctaaagc ttcgtatatt atttcttttg ccctttttag tggagctgct
    75301 actgacgttt ttatgtttgg caaatgttca aatctttctg tatttttagg tgctacatct
    75361 gttgcatata ttattgcatc tgcctttttt attatatctg gtgtatgagg gtccaccata
    75421 ccattagctc cttgcttttc tacatacaca tccacaccta tttctttacc agctttaatt
    75481 aatgcttctg ctgacatata tgtatgtgct atacctgcag ggcatgctgt tattgctaat
    75541 acaatttttt ttgattcatt ttgaatccta atctcttctt ttatttgttc tttcttttct
    75601 tttatatcta agttattaaa taactctttc ttagtttttg aatttaacaa catattcata
    75661 taatcttcat tagacagtct agtaactaac tcagaaagta tttgtatgtg tgtatttcca
    75721 ccttcacttt ctggtactgc tattaaaaat attagctcta ctttattatt tgagtctacg
    75781 ctttcccaat tttctattgg tgtctctaag gtcatagctg caaatgcagc ttctttaact
    75841 gacttagatt ttccatgagg aattgcaagc cctttttcaa aacctgttgg agataaagtt
    75901 tctctgtaca ttacagcttc taaatattcc tcataagatg ttaacttgcc ttcatcatat
    75961 agctttcttg ctaagaactt tattgcgtct tcctttgttt ttattttttg ttttaaaaaa
    76021 acaaggtttt catttgtgat tttcttaaat tccaaaatta cgccctcctt aaatcattta
    76081 atgttatgaa tatagcataa aataaatcat gaaaatgttt ttttgaaatt atacacacaa
    76141 tttcttctta aaaaataaag atttgtgtat ttatacacaa atctctatct taaccagtat
    76201 tgttctatta ttgctctcat aatcatcata attggaacct tatctgatat attgtaccca
    76261 tttacttgtt taattgttga atagcaatat aaacttatat ctgcaatttg ttgcaattga
    76321 ttttcacata tatgtgttag agctactacc ttacaaccct tattaactgc tgtctttgct
    76381 gcttctataa cttctttcgt ttctccactt aaactaagcg cgaaaaacat atcttgttca
    76441 cctaattttc ctatatcatg aagtacttca tgtctttggc tatagtaagt tatattatca
    76501 tgcccacctc taatttcttt tactaatatc tcacataaag gaatgttttg acctattcca
    76561 taaactataa tactcctaga tttttgaatt atatctgcta ctttatttat tttttcataa
    76621 tctattagct ctaatgtctt ttttatatct gattcaaaac cattttttgg ctctttatcc
    76681 tcatttttta actcttcttt taaattgttt tttagttgag agaaaccatc atactccatt
    76741 tttttacata gcctaactat ggtatttggg acagtaaaaa atttatctgc taaagattgt
    76801 attgataatt ttactatttc ttctttgttt tttctcatat actcaattat catgtcttct
    76861 gtatctgtaa atttatactc atattttttt gctctttcat aaaattccat agtttctcct
    76921 ccatctattt tattattcat aaatataata ttctgtatta tctaaatttt ttagtaatat
    76981 ttttaatttt ttcacatata ctataccttt tattatacat aaaaaataag tacttcctat
    77041 attgatggag ataatttaaa agtgtgttgt ttaatatact tagttatctt ttgaatataa
    77101 tcgatttgac attatcatta acagatatta gaatttaaga tagattaatt tttatcgcaa
    77161 cttgataaat cataacttaa ttctatataa gtgaggtgaa aagagtatgt ttacagatat
    77221 aagaagcaaa cgagttatat ttgttgccca ttgtgtgcta aatcaaaatt ctatttcaga
    77281 tggtactgct gattatccta gcacaaatac ggatgttgtt cgtattctaa tatatttatg
    77341 ttattaacaa ggatgtaaag cctaatttta caaaggttct acatcctata ttcatttaca
    77401 gaagatgcat ttatcaaaaa aatcctaaaa ttttgtcagc aaactaatta tatatcttgc
    77461 tattttattt tgatttacac aatatttagt taatataaaa ccttatatgt tgatagaaaa
    77521 tcaacatgac ctttagattt aattgttagt ttttaaaagt tctttaaaag gtctctaaaa
    77581 tcaaccaact caatattatt tcttcttaac catattttaa cttccttatc acatagcatt
    77641 gcatgttcat atactctctc ttgaataaga gaagatgatt ttataagact ataatctata
    77701 aatcctggat gagtaaccct gaacctccca tgactaaagt cacagagttc ctgcttcata
    77761 gaattttgca tactaaaata tgtcttacta attctccaca ggctatcccc gtag
//
LOCUS       DACTZW010000006        71938 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.006, whole genome shotgun sequence.
ACCESSION   DACTZW010000006 DACTZW010000000
VERSION     DACTZW010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 71938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 71938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..71938
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.006"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(342..848)
                     /locus_tag="JAM15_02250"
     CDS             complement(342..848)
                     /locus_tag="JAM15_02250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016441535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HAT6797096.1"
                     /translation="MGFREVKIEELQFNPFTKIGKEWLLITAGDSEKFNTMTASWGGV
                     GVYWGKNVVTTYIRPQRYTKEFVDSNDTFTVAFFDETYREALNICGTISGRDINKIEK
                     AGLTPYFVDDTVAFEEANMIIVCKKLYHGNMPPENFDAKENDKKWYPEKDYHTMYISE
                     IIKVLVKE"
     gene            complement(1219..2247)
                     /locus_tag="JAM15_02255"
     CDS             complement(1219..2247)
                     /locus_tag="JAM15_02255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HAT6797097.1"
                     /translation="MKRVYIDFEMNMPNSKSKRAVFNSDIIAIGAVMYDEKTKNIDKF
                     KSLIRPVSNEELYPHIQELTHISSEELKSAPSYEEVMRKFKKWLGIFSDIKGIYTFGN
                     LDLTCFNNTDMRSAKKNNHPRFVNNIRDLFVDIKEKYINCGMRCMNYISLKNLLEFVN
                     LEFSGDAHDPLNDAYNLFILDEAITNNVDIQNLLIIRDIIRPPFNDINSNLDNCFNKF
                     KESLYKKEGNYNIVDFSVEIIKTVRMYLLTIIDVNIQNLEIMKDISKKMDTIDKLKDI
                     EEGYFYLLEDVYFDMKDVLEDLMLYRMNEDEYKHEIKNIIKMFDEDLDNEKIYINKCN
                     NLNVVNKI"
     gene            complement(2295..3155)
                     /locus_tag="JAM15_02260"
     CDS             complement(2295..3155)
                     /locus_tag="JAM15_02260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HAT6797098.1"
                     /translation="MSELSGKGCEIIVPFEERLPVRDIEKSIIKKYRKNLWSKFMKAI
                     RDYKLVEEGDKIAVAISGGKDSILMAKMFQELKKHGQVNFDVEFIAMDPGYHANIRQL
                     LIDNCEYLNIPIHLFDSRIFEIADEIAKDYPCYMCARMRRGALYSKAEELGCNKLALG
                     HHYDDVIETTMLNLLCAGNFKTMLPKLNSTNFEGIKIIRPLYYIREEHIIRFIQNSGI
                     WPLNCACMVAAKKTGNKRYEIKDLIKSLESNFKNVEKSIFKAAENVNLDSVLGWQKDG
                     EKHSFLENFE"
     gene            3424..3633
                     /locus_tag="JAM15_02265"
     CDS             3424..3633
                     /locus_tag="JAM15_02265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HAT6797099.1"
                     /translation="MENKTRDIKKNCGPSLARPYINNQIFTEMYCLSDALKFGTIFPE
                     LNLLESEMYNKELYAKPKKYRGGRR"
     gene            3633..3899
                     /locus_tag="JAM15_02270"
     CDS             3633..3899
                     /locus_tag="JAM15_02270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HAT6797100.1"
                     /translation="MKDSSRAELMRKVQETSFACVDMNLYLDNHPDDKNAINTYNSLC
                     NQFAQARYAYENKYGPLTNFGYAPSRCPWQWADQPWPWDREFNY"
     gene            3928..4500
                     /locus_tag="JAM15_02275"
     CDS             3928..4500
                     /locus_tag="JAM15_02275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011989244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HAT6797101.1"
                     /translation="MWIYQKTIQHPVNIKTCDPRMAKFLITQFGGPNGELAASLRYLS
                     QRYTMPTGNMRALLTDIGTEELAHVELICTMVYQLTSDASPEELKAAGLGSNYAQNGY
                     GIYPTDSNGVPFDVRPIAVMSNPVTDLHEDMAAEQKALATYYQLINLTDDVDVIDVLK
                     FLGQREIIHYQRFGEALMDAYELEESQKMF"
     gene            complement(4734..5924)
                     /locus_tag="JAM15_02280"
     CDS             complement(4734..5924)
                     /locus_tag="JAM15_02280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HAT6797102.1"
                     /translation="MNFNQKRIAASIMATAIIMPTMGNLAYANESEVESVSIESRTIT
                     GNAVNFRKGPGTNHESMGKLYKGDKVEYVGKEGSWVKVKYNGNTGYVHGNYVAINSLG
                     SSNESSDTSVKSTKVVTAKGLNFRTGPSTSSSKISTLGYGTEVGYISESNGWSKISSN
                     GRVGYVSSKYLGTSVNDSTNENVENSSNDLVKGTKVVTAKSLNVRTGPGTSHSKIATL
                     SYGTEVGSISESGGWTKVSYGNQTGYVSSQYLAEKGSVDTSIPSYSTNSPSQGADSVI
                     SFAKTLLGKPYVWGAEGPNSFDCSGFTQYVMKKSAGVSIPRVSRDQSKYGTYVNRGDL
                     RSGDLVFFDTQGSNNGSVSHVGIYIGNGDMIHASSGSSKKVTISNINSSYYSSRYVNA
                     RRVL"
     gene            complement(6184..6615)
                     /gene="dut"
                     /locus_tag="JAM15_02285"
     CDS             complement(6184..6615)
                     /gene="dut"
                     /locus_tag="JAM15_02285"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HAT6797103.1"
                     /translation="MYNLKVKKLNDDAIIPNFAHKGDAGMDLYSIEEVVIPPGETKLI
                     KTGICIELPTMTEAQVRPRSGLALKHSVTVLNTPGTIDEGYRGELKIILINHGKNDFK
                     VEKHMKIAQMIVKPIYDINIEEVKELSDSERGKGGFGSTGF"
     gene            6728..8956
                     /locus_tag="JAM15_02290"
     CDS             6728..8956
                     /locus_tag="JAM15_02290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="HAT6797104.1"
                     /translation="MKLVLAEKPSVAKTIASFLGAKTRQDGYFEGNDYIITYAVGHLV
                     SLYDMKDYDKDKYSGSWKMNNFPFVPEDKFKFKIDSSKTKQFNTVKKLLNRKDVEYVI
                     NATDNDREGELIAFLIFLLAKNKKPVKRILVNEWTPEDITRGIKNLKDEDEMRNLQAA
                     GYTRLITDWLIGINFTSVATLKYGNGKLLNIGRVILPTVKLVYDRDMEILNFVPKTYY
                     EIEGHFKAEAGEYKGKYVKGKESKFDTLEDANKIIASITSETGKILDKKVTMSKEYAP
                     KLFSLTSLQGYITSKYSNFTSDKVLNVCQSLYEGNGKGGYITYPRTDSIFLEESLASK
                     ASQTLDKLKVGLEYENKIKFSKTKRVFDSSKVDSHSAIIPTYIIPKSLSKDEQLVYDA
                     IKDRFVANFMPPAEYENTEIKTEVDNCTFLTKGKVLKSKGYLEVYNKEEKNDLLPLVN
                     KDDVVDVLEIKPLTKQTTPPKPYTEDTLLKAMKNCGKNVPEEDTTVLSGYSIGTSATR
                     ADVLKKISQVGYVKKKGKSYSITDLGKNLVEIFPVKDLFDVDYTGKLEKSLSDIQKGK
                     YTRKEYLTNIISFIYQNVNIIKQDASKNINTEAYTFDSKTKKFTKTKEKKQKKDVTNT
                     EKEVAISKDSNNKKEVKNGDENQSLGKCPICQGDVLEFDKGFACKNHKECKFVIWKND
                     KYLSLYKKKVNKTMVKNILKKGETKVKSLTAKNGNKFDATLKYDKNPDTGYFNWKIEF
                     DN"
     gene            complement(9067..9552)
                     /locus_tag="JAM15_02295"
     CDS             complement(9067..9552)
                     /locus_tag="JAM15_02295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAT6797105.1"
                     /translation="MDNNNILKIADSFLDFLFVLENNIFKESDLLKKFQNNSDIMKAY
                     FEECPMAPSHAKVILYLMTSNSSSISQIASNLGILKSNMTPIIDRLVEHGLVNKFPDP
                     KDRRILRVELTDKAFKLFDAVKAILKESLVKKLSNLSEEELTLLDEHTLKLSEIVKKL
                     G"
     gene            9804..11027
                     /locus_tag="JAM15_02300"
     CDS             9804..11027
                     /locus_tag="JAM15_02300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HAT6797106.1"
                     /translation="MKRYLIVFLMCSSLFLVGCGKTEESEPEKPIAVSVQKAVGGEIE
                     NTNSFSGTTKVKDETAVTAQTVGTVQEVYVKLGQNVRKGDELLSISSPELENSVKQSK
                     ASLDLAKASYSSATGGSLEAQVNQAKTALDNAKIQYEESQRNYDNNKILYEQEVISLD
                     QFKKIEFSLEQTKQQLDSAQRAYDTATSKSIPQAKALAKKQLDQAQVSYNLAMSNLDK
                     LTLTSPVDGTITAKNFDSKEMITQSQPAFIISNPNILEVDLNVAESDIGKFKKDGNVD
                     VIIEDQRILGKIDYVPSVVDPQTSLYPVKVLVNNTNNKFKAGMSAQVNLSIEKENGAV
                     TVPKKAIFEENGKKYVYIATKDNIAKKHLVQTGIVTEDKIEIKSGVSDKDTVIIGGIS
                     LISDGTKIFPVEKEK"
     gene            11031..14165
                     /locus_tag="JAM15_02305"
     CDS             11031..14165
                     /locus_tag="JAM15_02305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HAT6797107.1"
                     /translation="MNLTQTSVKRPLTIIMVFLVLIVFGGIGYKKMSINLMPDIEIPV
                     VMVMTTWTGAGPQDVDEQVSQKVDESLSAVSNVKSTISSSQESVSMVVAQFEFGTNLD
                     EIMNDVRSKVDALQTSLPDDAAKPTVLKLDMNAQAIGQLVISGGNENSSQALRKYAED
                     VIQPKIESIDGVTSADLKGGKKAQVNVIADPAVLSNYGVSLSSIKGVLSSSNKTFPYG
                     SITQGEDKIVLRAIDKLESLDDIKQIQIPVKGGNTVRLDNLCSVDYGYADKDSIYRYN
                     GKDSLVIDISKQQDANTVKVMQSAYKYVDELNKENPQFKIKIANDTSSYISESINSVM
                     SNLLISAVIAFIVIFAFLKSVRASLVVAVAIPISIIGAIAILYFTGESLNLITASSLV
                     ISVGMVVDNATVVIENIFKYRKSGRLSLDDCAIEGTRTVTNAILASTLTTIAIFLPIM
                     FTEGIAKITFGALGKTLIASLAFSFIGAITLVPSVFAKLSRGKNSQKMQEKDSPIFDK
                     VSEAYKKLLSVCLRHQRLVVISSLLIFVASLFGMGFIGMDFMPAADKGELSISIELPK
                     GLSLESNDYYVSMTEKKVSDIPEIKTLITTLTSDSNNSKASIAIELESQKNRKRTTDE
                     IEKEIIDRVATVPDCKINVSQNSSVMGGAGGADFTLEMKGPDLDVLKILGKEAEKEFS
                     SIKGFRNVETSLTDTTQEAQFTIDKHKAQEYGVNTAEIAGMLRTAINGDSVTTATIDD
                     YKVDVNLKFKADTIDSLEDIKQLKVNSATGKEVPLGAFSDIKMADGLQSISRTDGDFS
                     VNITATLDNLDAGTATKLALEKTNKMVIPKDYSIGVGGETEMMNESMTSLGFSMVIAI
                     ALVYMVMVAQFESFSKPFIIMFCVPFAFVGVVLSLLVSGQSLSTVGMLGIILLIGIVV
                     NNGIVLIDYIEQLRKTNRNNDLIGLVSIGCAARLRPVLMTTATTILGMLPTALSLGEG
                     GETMQPLAIVIMGGLTVSTLITLVLIPTIYLIFDKWENKFSDKMPKIFGKITDKIGSI
                     KRKIIKKPKLKAKV"
     gene            14199..15518
                     /locus_tag="JAM15_02310"
     CDS             14199..15518
                     /locus_tag="JAM15_02310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HAT6797108.1"
                     /translation="MSKIVAIGCGVGIITANLIPVYADNNTSSINKVDNSILSDSNKR
                     TSEKEILTAREAVSAALKNSEKLKMKSEEIKMLKEKLEVQDEFDSFTGSDNSFPYDQI
                     GLLKNQSEQAKGFMEDQIANDITNKFNDLVSRENELDKIKNNLEIKTKEIKDMKLKKD
                     LGLVTSLETESAELELQTLQNTQKAKLQELKNNQDYFKLLTNIDLNNYQLDKEYRFES
                     FRVGGSVDSYMEGKVNEYLKYDQLILERTEESFNDKDENKADLPDRPELKKPTVPPKP
                     IKPSLDKFSTQEEYIKALDEYNKKLDEYESAINALNQYNAEKTNYATGLTTYANYLQQ
                     KFNTENGLVTLEDSKKALKKGLIDSYAQLLALEDTIQITKKQLDLSEKQLKNTKLRYD
                     LGLITLTDYKKQVVSNEDAKNSYDTLIVNYNSLKNGIEKPWILNNGK"
     gene            complement(15807..16052)
                     /locus_tag="JAM15_02315"
     CDS             complement(15807..16052)
                     /locus_tag="JAM15_02315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797109.1"
                     /translation="MTKCPKCGKEVSSRPGSICPRCGFKVADESLKIRCPEPSCRALV
                     SRKLDYCPKCGCKLRGYNISEFVNMVRCKIDETFDKK"
     gene            complement(16266..18893)
                     /locus_tag="JAM15_02320"
     CDS             complement(16266..18893)
                     /locus_tag="JAM15_02320"
                     /EC_number="2.7.9.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HAT6797110.1"
                     /translation="METKYVYSFGEGSKDMKSLLGGKGANLAEMTKIGLPVPPGFTIT
                     TEACNDYYVNNESIRAEIIKEIEEHLATLEKDLNKTLGCNKNPLLVSVRSGAVFSMPG
                     MMDTILNLGLNDNSVVGLAEATQNERFAYDSYRRFIQMFSDVAMEVPKYKFENVLDRV
                     KEAKGYTVDTELTTDDLKEIVKEFKAIYKKEIKNDFPQDPKEQLMLAIEAVFRSWNNP
                     RAIVYRKLNDIAHNLGTAVNIQSMVFGNMGETSGTGVAFTRNPATGENKLFGEFLMNA
                     QGEDVVAGIRTPQNISTLADVMPAVFDEFVKITHILEGHYKDMQDIEFTIENERLYIL
                     QTRNGKRTAAAAINVAVDLVEAGIIDEKEAIMRIEPNQLDQLLHPKFEDKALKEAKVI
                     AKGLPASPGAASGKVYFNADDVVKANEKGEKVVLVRLETSPEDIEGMVKAEGILTARG
                     GMTSHAAVVARGMGKCCVAGCGEIKVDEFNKEIRALDDVVIKEGEYISIDGSTGNVYL
                     GDVKKTEVSLTGNFEKLMNWVDKHKCMMVRTNADNPRDARAAIEFGAEGIGLCRTEHM
                     FFDEARLPAVREMILSNTVEQREKALEKILPMQREDFVELFKVMDGKPVNIRLLDPPL
                     HEFLPHDDETIEELSKSMGIKVSDIKKRIVDLDEFNPMLGHRGCRLAITYPEICVMQS
                     KAIIQGAIEAIKAGVKVSPEIMVPLVGEVNELKIIRKMIVETVDAIIKEEGIEVPYTV
                     GTMIEIPRACLTADEIAQEADFFSFGTNDLTQMAFGYSRDDAGKFLGQYVDEEILEKD
                     PFQVLDQNGVGKLVKMGAKLGREVKPELKLGICGEHGGEPSSVEFCYSVGLNYVSCSP
                     FRVPIARLAAAQASIKNPR"
     gene            complement(18954..19796)
                     /locus_tag="JAM15_02325"
     CDS             complement(18954..19796)
                     /locus_tag="JAM15_02325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HAT6797111.1"
                     /translation="MLVKNLIIYAVSDSVGETAQQVAKACMSQFYVNETYEIKRFPYM
                     INKGVLLETLENAKAENALIVYTLVDEELCSIVERYCEREGLSCIDLMTDILREISKR
                     TGRKPKREAGIIRKLDESYFKRVEAIEFAVKYDDGKDPRGVLQADIILVGISRTSKTP
                     LSMYLANKNIKVANVPLVPEIPIPKEVFEIDTKKIIGLTNSPEKLNEIRTQRLKALGL
                     SSKANYANLERILQELDYSEEIMKRIGCPVINVSNKAIEETAGIILDIMKENGLKIYK
                     EIEI"
     gene            complement(19803..20441)
                     /locus_tag="JAM15_02330"
     CDS             complement(19803..20441)
                     /locus_tag="JAM15_02330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6797112.1"
                     /translation="MIIIQLNERQLKIIDIVKENEPITSESIASSLNVTRATLRSDLA
                     ILTMTGILDARPKVGYFYSGVSEINLIGKSVKEKTVEDIMSMPVLAKKDESIYDVIVT
                     MFLSDVGSIVIIDENEELCGVVSRKDLLKATIGGSDINKMPIGMIMTRTPNVVTLTKG
                     ASVLLASRKIIEHEVDSIPIVEYKGEDKNHMRVVGRISKTNITKLFLEIVDN"
     gene            complement(20877..22169)
                     /locus_tag="JAM15_02335"
     CDS             complement(20877..22169)
                     /locus_tag="JAM15_02335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HAT6797113.1"
                     /translation="MLDLNRKLAKLEEEGKKIKVALIGAGHMGNGMVSQMANMKGIEA
                     SIVVDINLELAHKAFTDAGIDEEIIDNVTNEKDAEIKLQEGKVLTCNDFLVACKTKSI
                     DVVIDATGGIAIGAEIALNSILNKKHIVMLNAETDCVVGPILKKLADDAGVIFTGSAG
                     DEPGAVMELFDFADAMGFEVRVIGKGKNNKLDLDCNPDTVREEAERKGASPHMIASFK
                     EGTKTMVEMALMCNATGFVPDVRGGHGIEATVNEVPKKYALKSEGGVLDNYGVVDFVN
                     GIAPGVFVVVAHKLKAVNDELKYLSMGDGPNYILYRPYHLCSLETPLSAAMAVLEHKA
                     TIVPKAGLVAEVMTIAKKDLKKGEFMDGYGAYTCYGTIEKYDVAKAMNAVPIGLISKK
                     TKVVKDIKKGEVITYDMVEIEKDTTLYHLRQLQEKIFG"
     gene            complement(22206..22562)
                     /locus_tag="JAM15_02340"
     CDS             complement(22206..22562)
                     /locus_tag="JAM15_02340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HAT6797114.1"
                     /translation="MKYEVKISGIGSLVKELMDESNCLIIYDETINDDDLKDISVVHS
                     IATLKSDVEIGDTLTIGNRDYCIVSVGDIAQKTLREIGHCTIKFDGKCEVNLPGEIHV
                     EIGNPDITIGDLITIS"
     gene            complement(22597..22956)
                     /locus_tag="JAM15_02345"
     CDS             complement(22597..22956)
                     /locus_tag="JAM15_02345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797115.1"
                     /translation="MKLLVILFVAYILNTIFIMKQNKLYFKTLNRAKKKGDIVSTGKK
                     KSYFSKGSIAIISSDSDGFIKFGEILKGRTVMAKFKEIEEIEGLDIYSAEQKFKDEES
                     IVQAIKFIKEKINVSFN"
     gene            complement(23025..24998)
                     /locus_tag="JAM15_02350"
     CDS             complement(23025..24998)
                     /locus_tag="JAM15_02350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HAT6797116.1"
                     /translation="MSVTEKIPSIDRKIFKILIMCSKKEFVSINSIANELNVTTRSVR
                     TYIKQLNKDLGNDIAVIKYIKGQGYKLEIKDEQILNKIIDMNRKNVFSLNSKEDRVEF
                     ILNYLIELDGFITLDSLADEMCVGRTTLVNDFQYVEKVLASYNLNLIKKQNTGMKLNG
                     NELDIRLFILNQLYKNSRKDFSNSKYFKGIKKEEIINLEEKLLTLFKENNFYVTDEML
                     REVINYIVVLVYRVKEEKKVKDYDVKFDLLKSYDEYFIAREIKHIISGMFECTLNDEE
                     IIYLTIPLVSGNAPASECALNSSRISKNIDELMENIFNQIYVDMGIFINEDELRVGLG
                     YHLSFTLNRLLFNIKLKNVLLEEIKQNYILPFKLAQIAGKVIEKKYNLEVSEDEIGYI
                     AIHFSGYLERNSSRFYSIKKIAIICSTGLGTAKLLKIRVEKLIGNNPKIDTLSSFNLR
                     NINLDEYDIVFTTIDLDTSNINTIVLKINTIFDENKLREQLKTVLCLREGNIDTTNST
                     NLLINNLLDEDKFMILNEKTILASLEKMMDHLMDLGCIDDKFRKNIVNREEKSPTVFD
                     KGLLFPHSVNEKSDKFLMAVGILEEPIEYANRSIKIILMTMFPCENKIDSDLLVKIYE
                     EVLKIGQDVKLTNKISKCRTFLEFKKVLLKNLI"
     gene            complement(25220..26233)
                     /locus_tag="JAM15_02355"
     CDS             complement(25220..26233)
                     /locus_tag="JAM15_02355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HAT6797117.1"
                     /translation="MEENKILKIERGASGWGGPLYIKKEGNKNKILSMTAGGIHEVTF
                     KIKELLGCEIVDGFKTGVSDEEVAVVIIDCGGTARCGVYPKKKIPTINVNPVGKTGPL
                     AKFITEEYYVSDVNPNCISVVDGEDMPQKSQENKSENKSSIRKPDNYDEVKSKAQGEY
                     AKKNIILSIGQGAGKVVSKFYDAGRDTIQMVMNNVIPFMAFVSMLMGIILASGLGDWI
                     ARVISPLAGNIGGLLIISIICTLPFLSPILGPGAVIAQVVGTLVGTQIGLGAIPAYLA
                     LPALFAINGQAGCDFVPVGLSLGEAEPETVEYGVPALFYSRLITGPIAVIIAYGVAVF
                     ALK"
     gene            complement(26246..26791)
                     /locus_tag="JAM15_02360"
     CDS             complement(26246..26791)
                     /locus_tag="JAM15_02360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sorbitol transporter subunit IIC"
                     /protein_id="HAT6797118.1"
                     /translation="MENVITGLSKGAEWFIGLFQKGGEQFIGLVSGTLPTLIVLMVAI
                     NSLIKIIGEERVNNWASKLGRNSFTRYVLLPLVSVFFLGNPMCYTFGRFLKEEHKAGF
                     YDAAVSFVHPITGIFPHANAGELFVWLGISAGLTTLGKETTTLALWYFIVGLIVIFIR
                     GIVTERMYAFLTRKNKVTNKA"
     gene            complement(27166..28035)
                     /locus_tag="JAM15_02365"
     CDS             complement(27166..28035)
                     /locus_tag="JAM15_02365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAT6797119.1"
                     /translation="MDYLKYFEKAVMYIENNLHENITVNDVAKETGYSYYHLTRLFKS
                     MFGESVGSYIKKRRLVSSTKELLYSDKKVIDIAISSGFESSEAFSRAFKSIYKVSPIE
                     YRKNRIDVFVAKKKKLELDFMRHLVGNITIKPVIKEIEEIKVIGIKDKVILENNSLPD
                     LWEKFRKVHNIVQNTLPSKRVFGICEATSEIHLVSESMEFNEIIGFEVNSYDVIPNSF
                     VSKTIKEGKYAIFTHTGSLENLDKTYEYIWGTWFLSSKEELDIRDDFEVYDERFLGPN
                     NVNSQIDIYIPLK"
     gene            complement(28187..29302)
                     /locus_tag="JAM15_02370"
     CDS             complement(28187..29302)
                     /locus_tag="JAM15_02370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HAT6797120.1"
                     /translation="METLEVRNIELSGTNYEIGYRLGELVANMPEIIEGQINKSNLVS
                     KKEEKEMIELFDKYCPGLNEELQGFADAIQVNCNQILYYTMTYLKPGCSQVALAPELT
                     ENGHVLFARNFDFSHNMEDFVLCKTKVNGKYAHIGTTVMQFGRGEGMNECGLGVSQSS
                     CGIPVGNSDGLRKPAIVGLQFWAVIRYLLENCKDVDEALEYLKDMPIAYNINLLLADK
                     SGNIALVETLDGKKEVNIINSLESKREYFLHSTNHTHIDKLHKLEPQSMKNSIHRYKL
                     IKEYINKSKKIGEKELMNLLSSKYPNGLSCNYYNDFFGTLKSIVMDLNIGKFNILWGG
                     LENKWESYYLKNDIKSITQRININIEKAPSDFFDFIE"
     gene            complement(29538..30674)
                     /locus_tag="JAM15_02375"
     CDS             complement(29538..30674)
                     /locus_tag="JAM15_02375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HAT6797121.1"
                     /translation="MKERIIQVADSKKEKILGLCQSLYDEPEIALQEYKSAKKISEFL
                     REEGFDVEENLAGMATAFKATKKNGDGPKIAFIAEYDALPGNGHACGHHLIASMGVGA
                     GIALSSILDTYKGEVSIIGTPAEETGDGKPYLIEHGVFDGYDAAMMIHPNSKTCVTPE
                     IIAIGGLDFIFTGKASHAGAKPYNGINALDAVVLLYNNINALRQQLVDGTRIHGIILE
                     AGTAANVIPDMGKVRLEIRAKEQNYFDEVVEKVKNCARGAAIATGCELEFYHFEPTCQ
                     GLNENKVLVDIFTKIMEEFGIYEDEQVMLGSTDMGNLSQIMPCIHPLMKFSENGEELH
                     TKEFLEASINSYAKDRVIDGIKILALTGFNLFENPELLKKMKEE"
     gene            complement(30730..32193)
                     /locus_tag="JAM15_02380"
     CDS             complement(30730..32193)
                     /locus_tag="JAM15_02380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HAT6797122.1"
                     /translation="MTDLVNTINGIVWSPVLVAMCLCIGLYFSMKLRFFQIKDVKEMF
                     TLLLEGDSSHVGISSFQGFATSMAGRIGTGNIAGVAVAIAMGGPGALVWMCIMATLGS
                     ATAFVESTLAQIYKDEHDGQYRGGPPYYFEKGLGWKKCSILFSVVAIISYTFFMPGTQ
                     SNTLYLAMNQAFGFSKMTIAVTSSIALGIIIFGGIKRIGLFAEKVVPIMGGAYLIMTL
                     VIIIANINLVPGAIMTMFKSAFGFGSVFGGMLGSAISWGVKRGIYSNEAGEGSGTYGA
                     AAAEVSHPAKQGLVQAFSVYVDTLLICMATGIMIIITGMYNVTDVYTTLPGVEPGPQY
                     VQSAINTLHPQLGDIFIAIVLLLFTFTTLLAFSYMMETNVSYLVTRIKAEKHEKHIIN
                     VCRFMLIICAAMCCFIEPLTSWALGDICIGVLTYINLVGIFTLKKPAIKAYYDYQRQK
                     KMGVKRSDRTFNPIELDIRNAEFWENRYLKEDKHELN"
     gene            complement(32769..34031)
                     /locus_tag="JAM15_02385"
     CDS             complement(32769..34031)
                     /locus_tag="JAM15_02385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAT6797123.1"
                     /translation="MGEKENGIKFGKLMFQLVIIAISWELVYIIPFIQYTLYDPILKA
                     LECTNTQLGFLLTIYGLGNIFGAPIGGWLADRFDYRKIILGSVFLNGVVSFLFAFNMN
                     YPFAVATWVGCAITSLVMNYPSMVKILRVIGKDNQGKVYGFNEAMVGVSGVVMGAIFL
                     YIYTCFSTPVLGMRWVMISLGILSIVMCPVLWFVIKDVDIREDKEEEASEKMSAGDFM
                     TVLKSPNTWLVGISIFCVYSFTVTMSYFTPYITSVLGGSVALSGALAIIRQHGLKLFG
                     APFGGYCADKVKSPTKVLLPIYVFGIAVIILFLVLPASTPMTIFIALTFVVGILGYMG
                     KGIYYAVQDEVKVPVKYSATTIGIAAALGFSPDVFQFALIGHWIDTYGNKGYTYTFIF
                     QIAILIIGILSCLYILKVKKKRESKLEA"
     gene            complement(34055..35263)
                     /locus_tag="JAM15_02390"
     CDS             complement(34055..35263)
                     /locus_tag="JAM15_02390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAT6797124.1"
                     /translation="MKYAKRMDMVKASAIRASQKKIAQKVASGGTVISFAAGLPDPNL
                     FPIEEISEVTQKVLSERGKFALAYGPTKGEDELLELLVKRMKEEENIDTKAENIIITT
                     GSQQGISLSAMILLEKGDIVVTENPSYLGAINAFRPYECDFLGVDTDDEGMVTDDLDK
                     LLSENSNIKVIYVIPTFQNPTGKTWSLQRRKDFMEVVNKYDVIVIEDNPYGEIRFTPE
                     PLPTLKSLDTKDKVLYLGSFSKVLCPGFRVAWMCGNVDIIDKAELLKQGIDLQSNQFS
                     QVQVIEFLKKYNLNEHIEKIRAEYKKRCLLMLDAMKKHFPEEAKYTEPDGGMFIWVEL
                     PESINVDDLLDKAIDAGVAYVSGESFFANNGPKNTMRLNYTTMSEEQIVKGVEILAEV
                     IKKELNYACE"
     gene            complement(35293..36186)
                     /locus_tag="JAM15_02395"
     CDS             complement(35293..36186)
                     /locus_tag="JAM15_02395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HAT6797125.1"
                     /translation="MLKDFNNLLEEAKKLEPVIVSVAVAEDKEVLKAVKSATDLNIIK
                     PILVGDKDKIESISREIGLKGHEIIGCQNPDESVKKAVEIVKNKEAKVLMKGLVNTSV
                     YMRAILNKETGLRTGRLLSLLAVYELPQYHKLLYCTDSGINVSPNLNQKKDIMINALL
                     TMKSIGMENPKTAILTANEMVDHKIQSTVDANLLVEMEKSGEIPKCIAEGPIAFDVAF
                     DAHAAEHKGIKSNIAGDVDLLVFPNIEAGNILGKSWLRFNQAKWAGIVLGATNPIILG
                     SRSDTAEIKINSIALACLASQ"
     gene            complement(36204..37262)
                     /gene="buk"
                     /locus_tag="JAM15_02400"
     CDS             complement(36204..37262)
                     /gene="buk"
                     /locus_tag="JAM15_02400"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HAT6797126.1"
                     /translation="MKVLVINPGGTSTKISVFQDENEILKKNITHTREDLKNFSKVFD
                     EYDYRKQLIVDILSSENHSINSFDAVVGRGGLMKAIKGGTYTVSEEMIEDMRNEINGE
                     HASNLGALLAKTIADEIGVQSFVVDPVSVDEFDDVSRITGISDIEKASWLHALNHKAV
                     SRKIAQKLGGKYEDYNFIVAHLGSGISIVAHKQGKMIDGSGGRSDGPFSPERSGGLLA
                     YPLIELCYSGKYTHDEMVAKVSSIGGMYDYLGTKDMIEIENRIKEGDEKAKLIMDAFI
                     YQVAKEISMYGASLSGNVDRVILTGGISHSEMVVKGVAEKVSYLAPIEIVPGEMEMEA
                     LALGALRVLNGEEIAKTY"
     gene            complement(37419..37958)
                     /locus_tag="JAM15_02405"
     CDS             complement(37419..37958)
                     /locus_tag="JAM15_02405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HAT6797127.1"
                     /translation="MLNEIICAGFGGQGVLTAGKIIMYVAYKAEKKITWFPSYGNEMR
                     GGSANCNVVVSDEKIANPCVKNPDILLGMNSVSVDKYESLMKKNGYMFVNESLVSKDR
                     KYREDINVIKVPVTEIAQNLGNEKAANICMLGAMVKSLDLFTKEEFESGMCEYFENQG
                     KGKFNSKNVEAFEAGYDYE"
     gene            complement(37971..38690)
                     /locus_tag="JAM15_02410"
                     /pseudo
     CDS             complement(37971..38690)
                     /locus_tag="JAM15_02410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454726.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
     gene            complement(38693..39769)
                     /gene="vorB"
                     /locus_tag="JAM15_02415"
     CDS             complement(38693..39769)
                     /gene="vorB"
                     /locus_tag="JAM15_02415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HAT6797128.1"
                     /translation="MQSLLIKGNEALAEGAIRGGCRFYAGYPITPQSEILEMMAWRQK
                     EVGGVFIQGESEIASVNMVMGASALGARAMTSSSGPGFSLKQEGIAYWVSAGLPAVVA
                     CVQRYGIGDGFIGAGQDNYWQAVKGGGNGDYHLIVLAPNSVQENMDMAYESFELAEKY
                     MHPVLILSDATIGQMVEPCIAPPMKEYDMDKAPWAAKGTPVGEKNKVITDITYFEDQD
                     TWQKGYIEKMRKVQEDEQRWEEIEIEDAEVVFVAYGISSRIAEGAVRDARAKGMKLGL
                     IRPKTLWPYPRKAFKKLSDSLKGLVTVEMNMMAQMKEDVIIACDNRFPVYSVATAQYM
                     AEVNQLIDFAQQIIDGKAKQEEVF"
     gene            complement(39798..39995)
                     /locus_tag="JAM15_02420"
     CDS             complement(39798..39995)
                     /locus_tag="JAM15_02420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HAT6797129.1"
                     /translation="MEKVKLSVERCKGCYLCIEACKKDAISLSDYTNKKGFVTIKVDE
                     EKCIQCGACYTMCPDLVFEIL"
     gene            complement(40278..41045)
                     /locus_tag="JAM15_02425"
     CDS             complement(40278..41045)
                     /locus_tag="JAM15_02425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HAT6797130.1"
                     /translation="MGEIINALDRALDIILLLYHEKREMGITEISKAMGVYKSTVHRT
                     LVTLENKGFVIQNAENGKYWLGINLYAIGMVVGEKMSLTEIVKPYTKKLNQEFNEVVN
                     VSILEERAQDSPRSIIIHKEYGSNQLLSVNPSVGSSSECYCSAVGKCLMAFNDSIDFE
                     KYRKTPIHKYTEHTIDNWDDMMLFLAKIKEQGYAIDDEELEHGLTCIGAPILDKNNKA
                     IAAISLSGPTIRMREGDFEYKIKRVIETAKSISELFR"
     gene            41325..42872
                     /locus_tag="JAM15_02430"
     CDS             41325..42872
                     /locus_tag="JAM15_02430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite/sulfite reductase"
                     /protein_id="HAT6797131.1"
                     /translation="MDNFKKILLNELPNFKEYSSKFLNGEINKMQYKGFSGGYGVYAQ
                     RDKKSFMIRLRVSAGVLSQYQLNKIYEIAIKHNLDKIHLTTRQAIQLHDLSINSIVDI
                     MEEGIKNDIFTRGGGGNYPRNVGLSPLSGVDPSEVFDVTPYAVATDKYFIKNATTYHL
                     PRKLKVSYSNCYTDTAHCSIQDLGFVATLKNDEPYFRVFLGGGLGKQPKVALELDELI
                     KPKDALYCVEGMIKFFMDYGNYENKNRARVRYMVESLGEELFLEKFKEYYKLEKENGS
                     LELNIEEIDYSKPGVKIDIQDSRLIPQKQDGLYTVYIHPVGGILLTKDLSTLLKELDN
                     VENPMIRLGMTEGLYILNLNGNEAKRILEISKTISCNSQLEQSISCIGVPICQMGIQN
                     SQKMLHEIIDYFRLQNNEEILNKAPKLYISGCLNSCGVHQVGSIGLCGKKKNVDGIST
                     DAFELFVGGSFEIGKTRLGKSLGDFKASDIPEMLYKISDASSGNFYEWVNSNDNILNK
                     ITDKYKI"
     gene            complement(43038..45104)
                     /locus_tag="JAM15_02435"
     CDS             complement(43038..45104)
                     /locus_tag="JAM15_02435"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HAT6797132.1"
                     /translation="MKNYLLFEIGVEEMPSRFVGSTLEQLKNNLSKLFDENRIAFDKI
                     NAYGTPRRLTLVVEGLSDRQSDLEEEIKGPAKKIAVDAENNLTKPALGFIKSKGLSES
                     DIYFKQVGKEEYIFATIKQDGKETSEVLKDILPETIKSVVFPKAMRWGGKNLKFARPI
                     RWIVALLNDKVLEFDLEGIISSNVTKGHRFLGESTIEVDSIEDYFEKLEKNYIVLDQN
                     KRKEMIRKQCIEVANSLGGEVEFDEDLLEEVTYLVEYPTAFYGEFDVDYIKLPKEVVI
                     TPMKQHQRYFPVLKEGKLLPNFIAVRNGDSYRIDNVKAGNEKVLEARLADALFFYRED
                     TKRNLESYIEKLKTVVFQVKLGTIYDKTLRLEKLSADILDSLGLVDEKADTIRAAKLS
                     KADLVTGMVGEFDELQGFMGKEYAKVGGENDVVSEAIFEHYLPRFAGDILPKTNAGVA
                     LSIADKLDSIAGFFAIGIQPTGSQDPYALRRQALGILSILMDRKVAVDIKVLIEHALD
                     NYSELDFNKEEVVEQIMNFFNERVKNLFKDLGIRYDVVDAVLSSDINDVSDMHMRALE
                     LNNWLEKDELVEMLTAFNRVSTLAQKAESDKIDESLLKEDAEIRLYNEFKQVKVKVNE
                     LLKDKKYGIALDEFASLRPVVDNLFDTVMVMDNDEAIKNNRLALLKQVYDTMLEICDL
                     SKIVYK"
     gene            complement(45104..45982)
                     /gene="glyQ"
                     /locus_tag="JAM15_02440"
     CDS             complement(45104..45982)
                     /gene="glyQ"
                     /locus_tag="JAM15_02440"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HAT6797133.1"
                     /translation="MNFQEMILALQKYWSKQGCIMMQPYDIEKGAGTMNPNTFLRSLG
                     PEPWQVCYVEPSRRPADGRYGENPNRLYQHHQFQVILKPSPDNIQELYLESLKEIGID
                     PSEHDIRFVEDNWEAATVGAWGLGWEVWLDGMEITQFTYFQQVGNIECELETGEITYG
                     LERLAMYIQEVDSVYDLKWNDKITYGEVFNKAEYENSMYAFELCDADMLFNLFDIYEK
                     EALRLMENGLVIPSYDYVLKCSHAFNTLDARGAIGVSQRASFIGRVRNMAKTVAETFV
                     KQREEMGFPLLKDGDK"
     gene            complement(46142..46741)
                     /locus_tag="JAM15_02445"
     CDS             complement(46142..46741)
                     /locus_tag="JAM15_02445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4342 domain-containing protein"
                     /protein_id="HAT6797134.1"
                     /translation="MSSNITIEMVDSVFERVPGATYAEAKEALVMCNGDVIEAVIYLE
                     NKKNTCNCKAKSAKETMEEVFGKDGENIKFQLKELLRKSSVVRIIVEKDGKTMMNIPL
                     TVGVVGLAFVPLATLVGLSAAVISKYRIKVQNEEDGEIVDLGELNEEKLHVLKNMITN
                     AAKDVKDVVVDKKEDDKDVTADLMKEESEKNKEDEDENK"
     gene            complement(46734..47507)
                     /gene="recO"
                     /locus_tag="JAM15_02450"
     CDS             complement(46734..47507)
                     /gene="recO"
                     /locus_tag="JAM15_02450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HAT6797135.1"
                     /translation="MIILNTQGIVLKAIRYKESDIILTLFTRKLGKVSAIAKGAKKNK
                     SSLLSSSQLFSYSNFTLKKQGNMYKVTQSEIIKSFYNISYDIEAFSYATYITKLVENS
                     ILENQTNNRLFILLAQTLYLYTQDNTDNRFITAAFELKFLDYIGFKPIVNKCINCECK
                     ILQNSVFNIYEGGILCSKCSKLFDNNIKLDLTTISLMEYVLRNDILTCSKAKVSKYIT
                     HELENILDKYLKVYVDNINFKSLHVLQSVKNNKGVDNDE"
     gene            complement(47473..47628)
                     /locus_tag="JAM15_02455"
     CDS             complement(47473..47628)
                     /locus_tag="JAM15_02455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqzL family protein"
                     /protein_id="HAT6797136.1"
                     /translation="MNNISWEVFKKTGSIDAYLYFCDCKNIHEEIEEVREKKEDDDNP
                     EHPGDST"
     gene            complement(47701..49080)
                     /gene="mgtE"
                     /locus_tag="JAM15_02460"
     CDS             complement(47701..49080)
                     /gene="mgtE"
                     /locus_tag="JAM15_02460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HAT6797137.1"
                     /translation="MDRKLDASQDLLYEVKSLIDNNKVLELRELIEEYHIIDIFDIME
                     NLEEDMKIQLFEVLPLDMASSILEEGSVEFFISILSKLDVEHSKNILELMSLGDMADK
                     LSELEEEEREHIINLLNQENADYVKELLFYDEDSAGGTMTTGYISINKDMTALEAIDH
                     MREEAEEAETIYYIYVVDDEEKLVGVLSLRELIIARDANIVEDLMSENIISVYVDEDR
                     EEAVRLVSKYNLIAIPVVDRQEKLKGIITVDDIIDVMEEEATEDMYKFAGSSEHEREV
                     AEKENPTLREQIISALRGRLPWLIITLVGGLLASLILSNLDYIMNPVYAPLVFFIPVV
                     IGMGGNIGTQSSSVTVITLSNKDLNFSNVVREGIVGIITGLLCSIITGIVIYFVMRKL
                     DIVLIVSISLFINMVLGATIGAFMPVLLKKMDADPSTVSSPIISTALDITGIAVYFII
                     TTALLSKIV"
     gene            complement(49092..49985)
                     /locus_tag="JAM15_02465"
     CDS             complement(49092..49985)
                     /locus_tag="JAM15_02465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HAT6797138.1"
                     /translation="MFKSGFVSIVGRPNVGKSTLMNNVVGEKIAIMSDKPQTTRNTIQ
                     AVYTDEEMQIVFLDTPGIHKPKNKLGEFMVKAATEAFKNVDLILFVVDDSKKIGPGDR
                     KIIEDLRSVKTPIILVVNKIDQLDQKDELFDIIKMYDREGIFKEIVPISALKGKNTDT
                     LIKVIQNYLEEGPKYFPDYMITDQPERVLIAELIREKVLHYLNDEIPHGVAVEIEKMK
                     ARNDKEIVDVSAVIYCERDSHKGIIIGKNGRKLKGIGKSARQDIELLLGSQINLQLWV
                     KVKENWRNLQNYINNFGYNDK"
     gene            complement(50049..50450)
                     /locus_tag="JAM15_02470"
     CDS             complement(50049..50450)
                     /locus_tag="JAM15_02470"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HAT6797139.1"
                     /translation="MDNIELLRLAEDARQHSYAPYSGFRVGAALLTKSGKVYTGCNIE
                     CASLGGTNCAERTAIFKAISEGDKDIYKIAIASDNSENNEQTYPCGICRQVIIEFGSD
                     IKIITGYTKGEVFEHSIKDLLPNYFSGNDLK"
     gene            complement(50569..51288)
                     /locus_tag="JAM15_02475"
     CDS             complement(50569..51288)
                     /locus_tag="JAM15_02475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HAT6797140.1"
                     /translation="MKPEKTRQGIIKAFNAAIEGILYTFKFERNMKIHYLGSVAVLII
                     SLFFNFSKLEMIMLLMSICLVVVAEMFNTAIEKAVDLVTDEYHVLAKIAKDVAAGGVL
                     VAALNSVVVGYILFYDKLTDISGILIYKIRESELHITLICILLVLIAVVVVKALTSTG
                     TPLKGGMPSGHAALAFAIATAITLMTERVVASTLAYIMAVLVAQSRIEGKIHTFWETI
                     AGALLGVLIAILVFQLGMFYN"
     gene            complement(51294..51755)
                     /gene="ybeY"
                     /locus_tag="JAM15_02480"
     CDS             complement(51294..51755)
                     /gene="ybeY"
                     /locus_tag="JAM15_02480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018591458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HAT6797141.1"
                     /translation="MDLILDDRQDKLEVSEELIEKVKDIIIECLDYEGYDDNYEVSLS
                     FVDNKEIHELNREYRGVDRVTDVLSFPLLSDDFEDVELEEESLGDIVVSLERALEQSI
                     EYNHSFEREVCFLICHSMFHLLGYDHDTDENTKEMREKEEHILNKLNITRE"
     gene            complement(51812..52828)
                     /locus_tag="JAM15_02485"
     CDS             complement(51812..52828)
                     /locus_tag="JAM15_02485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HAT6797142.1"
                     /translation="MIIQKKFTIADGNFERELFGNFDENVKLIEKTLNIDVILREGNI
                     ILIGEEKNVDSALKLMNELHQTVSNGKHLDKQSISYSLSLLLEGSEQKIKELEGTIVI
                     TQRGKAVQPKTLGQKEYIKLIENNDITFGVGPAGTGKTYLAVAMAVKAFKRDEVSRII
                     LTRPAVEAGESLGFLPGDLKDKVDPYLRPLYDALFEMLGADKFNKYLERGTIEVAPLA
                     FMRGRTLDNSFIILDEAQNTTSEQMKMFLTRLGFGSKAVVTGDVTQTDLPQNKKSGLI
                     QATEILKGVPGIGSIMLTDRDVVRHELVQRIIRAYEKHDKREEFKKEERKKAKMQEKT
                     FKRK"
     gene            complement(52866..54209)
                     /gene="yqfD"
                     /locus_tag="JAM15_02490"
     CDS             complement(52866..54209)
                     /gene="yqfD"
                     /locus_tag="JAM15_02490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YqfD"
                     /protein_id="HAT6797143.1"
                     /translation="MISFIRGYYVIVVEGVGLEQFLNHLIRNGISVYNVTRIKNTKME
                     FHIDRQDIKEFKNVYRGSKFDIKVKQKTGVPFIIKRVYKHKGMWICALVSLFLLMSTS
                     QFVTDVYIQSPEGIKKEALRNELYKVGVRPGVYKKSIDRKEVRDHMMSKFNDVAYLSI
                     NVKGTNIFVTVTKKAESLKSTDQSNYCNVIALKNGIIEKVIPRSGKSVIKSGDIVQKG
                     DVLLNGANTKSIPEVWASTFYESTKKASYVDTVNKKTGEKKNIYTLSFYDKEFTMRKN
                     IKYKDYVVENKEKKLSIGNYTFPIKIKTSTFYETKKVEVKRNKEELKKELSEKALKEL
                     EYIIPASARIIDVKHNFKVNKNMLEYLITVQTSENIAKIYPLSKSEAERFIKEESKPD
                     EGEEEIPSNPEKRPLNDIRNEFDEDNKDNKDQNNSDENNSNQNSNNSQNNNSNNN"
     gene            complement(54222..54458)
                     /locus_tag="JAM15_02495"
     CDS             complement(54222..54458)
                     /locus_tag="JAM15_02495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein"
                     /protein_id="HAT6797144.1"
                     /translation="MLEISTDLQVNQPVITVTSNTFISIENYLSILEYEVDLIRIKTK
                     VKTIKISGDKLSLKYITDSEIGIKGIIYNVEYVD"
     gene            complement(54671..55234)
                     /gene="raiA"
                     /locus_tag="JAM15_02500"
     CDS             complement(54671..55234)
                     /gene="raiA"
                     /locus_tag="JAM15_02500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HAT6797145.1"
                     /translation="MQIIVSGRQMKLTDGIKGYVDGKLSRLEKYLDPESEVKVTVSAK
                     KDRQKVEVTIIPINGQIIRAEDVEDDLYAAIDIVCDKLSRQVVKYKTKVKDKVQNNKS
                     IRFENLDFIDNSSEFDDYDYDDEEDENIVIERRKKFNVKPMSSEEAILQMELVGHNFY
                     MFRNQDNFEINIVYKRKAGGYGLIEQD"
     gene            complement(55427..55924)
                     /locus_tag="JAM15_02505"
     CDS             complement(55427..55924)
                     /locus_tag="JAM15_02505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HAT6797146.1"
                     /translation="MIISVKEIRNFLINIFIPLIIGYLSSILTMIISGTDISTYYLQL
                     TKPSFAPPAFIFPIVWTILYILMGISSYLILRKGYNLPKVRDAIFYYGLQLVLNFIWS
                     ILFFGFGLRFTALIDIIIMILVSIIMISKFSKIDKRSGYINLIYLMWLVYAGFLNYFI
                     WFINK"
     gene            complement(56035..56478)
                     /locus_tag="JAM15_02510"
     CDS             complement(56035..56478)
                     /locus_tag="JAM15_02510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HAT6797147.1"
                     /translation="MSLKQKLQEDLKSSMKNKDTVRKSVVTLIRASIKQYEVDNRVEL
                     DEDGIIDVIAKQLKQRRDALVEFEKAGREDLIKETEGEIEVLKEYLPQQLSEEELEEI
                     VKSTISEVGATSMKDMGKIMSVIQPKVKGRADGKLINKLVKQNLQ"
     gene            complement(56508..56687)
                     /locus_tag="JAM15_02515"
     CDS             complement(56508..56687)
                     /locus_tag="JAM15_02515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002844447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HAT6797148.1"
                     /translation="MSEVRVRENETLDSALRRFKRQCAMSGIMSEVRKREHYDKPSVK
                     RKKKAEAARRKNAKK"
     gene            complement(56850..57200)
                     /locus_tag="JAM15_02520"
     CDS             complement(56850..57200)
                     /locus_tag="JAM15_02520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine triad nucleotide-binding protein"
                     /protein_id="HAT6797149.1"
                     /translation="MDCIFCKIASGEIPSTKVYEDDRVLAFNDLNPVAPYHILVVPKK
                     HYDSLIDIPDKEMDIVSHIHVVINKIAKEKCFDQTGFRVINNCGSDGGQEVKHLHYHI
                     LAGKKLPNYEAGQN"
     gene            complement(57243..58541)
                     /gene="mtaB"
                     /locus_tag="JAM15_02525"
     CDS             complement(57243..58541)
                     /gene="mtaB"
                     /locus_tag="JAM15_02525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-
                     methylthiotransferase MtaB"
                     /protein_id="HAT6797150.1"
                     /translation="MKKVAFYTLGCKVNQYETEAMLELFEKDGYEQVNSEEYADVYVI
                     NTCTVTHMSDRKSRQYIRRVKKKNPDAIIAVVGCYSQVSPEEILDIEEVNLVMGTNDR
                     RKIVEEIKKINSSKKVSTVDDIMKVKAFEEIEISQTNGKTRAFMKIQDGCDRFCTYCI
                     IPYARGRVRSRDIDSIVDEVKKLANNGYKEVVLTGIHVASYGKDLKDRDIKLLDVIKQ
                     INQIEKIERIRLSSVEPILFTDEFVNEVLKMDKVCPHYHLSLQSGCDETLKRMNRRYT
                     TLEYKTIVDRLRSKMPDVAITTDVIVGFPGETNEEFKKTYEFLKEIELSQMHIFKYSP
                     RKGTPAATMENQVDPQMKHFRSEQLLNLSKVNFNKFATKFIGRELDVLFEQNIEGNKY
                     EGLTSNYIRVVVESDKNIQGQILKVKINDVKDEYVEGILL"
     gene            complement(58543..59301)
                     /locus_tag="JAM15_02530"
     CDS             complement(58543..59301)
                     /locus_tag="JAM15_02530"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HAT6797151.1"
                     /translation="MDRFFVEKNNINLQDKTCTIEGEDVKHISKVLRCKLGEKLEICD
                     KNNNEYICEIMNIDKSIVNLEILEKVDINRESELKVRLYQGLPKAPKMEMILQKLTEV
                     GVEEIILVQTKRSVVKVDDKKEDKKFERWERIIYEAAKQSKRGKIPKLRGVLSFKEAL
                     EDMKKNNVNICPYENERTVSIKHALKKCDSNIDSVGIFIGPEGGFSEEEIEQIQKNNC
                     NVVSLGPRILRTETASVVASTIALYELSDLGGEK"
     gene            complement(59320..60267)
                     /gene="prmA"
                     /locus_tag="JAM15_02535"
     CDS             complement(59320..60267)
                     /gene="prmA"
                     /locus_tag="JAM15_02535"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HAT6797152.1"
                     /translation="MNNWIEVTIKTTTEAVEPITNILYEQGAGGAVIEDPKDFLFQKK
                     NELDWDYVEEEVFKKNEEDDVLIKTYVSEEKNVMEFVEIIKQKVLGLKDFGIDIGEGS
                     VSLDQVNEADWANAWKAYYKPTKVGQRVVVKPTWEDYAMQDGDLIIELDPGMAFGTGT
                     HETTSMCIRELEKYVNKDSKVFDIGCGSGILAIAAAKLGAKEVVAVDLDEVAVKVAKE
                     NVLENKVEKSVSVMHGNLTDVIKDKADVIVANIIADIIKILAKDVQNFMKEDAIFISS
                     GIILDKVEEVKESLIENGFEIVEVQKLGEWSAIVSKLKK"
     gene            complement(60708..63116)
                     /locus_tag="JAM15_02540"
     CDS             complement(60708..63116)
                     /locus_tag="JAM15_02540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HAT6797153.1"
                     /translation="MKNIMQKEILAKSYNLRTNQQEQTLVEHIKDLFEVLESILELNL
                     YSDKDVEILKICCALHDLGKINSIMQQKMEINNKISYSCSEEERKKLESDKKSLKKIA
                     RHNIFSGAFLKDILEKMNLSEEDKLYIYKSIMLHHGNYEDYMRLSTSKVQKEIYDYIE
                     KGILEKEDFNLEDIEGYINKILDVDFKFSEDVLDYDYIDKLSESMIIDSDYNNGQIED
                     SVLNYRKFKYILYKGMLNLIDHSASSRQKGIKFYNDFTDEEIDDMILNEIYKSQGNLE
                     KNNIEFNTIQKRLRELSGRNVLTVAFTGSGKTAADYRKTFKRKFFLVPNKISAESFYR
                     KNIFQNKNDLDTRSSNDYIGLLHGDINLYSENEDNGEHDFVLTLRDIDLSINFCKPCV
                     IATVDQLLLSMFKFPGYEKIFAAVKNASITVDEVHLLEPKMFLILIYFMQFACKYLDV
                     DFHLMTATLPKSYKEQMINKGIIFQEESNENVTDKGEIVFIESNKEEEICEGKDVKVS
                     FIKEKEIKSIVEGALENKQKILIIKNTIDSVNRTYEFLKENLSDKYGGVDIDVLHSRF
                     KFKDKKEKYSKILNGEGNIWISTQSVEISLDLDFNIIISDLATMDSLIQRMGRCNRNN
                     KYEYGNFYILPSEDKIYDNKLKNTTKNILKDILKTNSIFTMGIRKTILDDYYDNSVVK
                     NYFEENFISCDKEIKNIYGINKEIFDGLDLIFNFEPYKNIVDSKKEAAKIFRDVDVSY
                     KIILEEDFYKEDRELQQDSIQVSGFIFNRLYYYGLISKVEGYMVLKSSSKFEYNSTVG
                     LILK"
     gene            complement(63143..63949)
                     /gene="cas5"
                     /locus_tag="JAM15_02545"
     CDS             complement(63143..63949)
                     /gene="cas5"
                     /locus_tag="JAM15_02545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas5"
                     /protein_id="HAT6797154.1"
                     /translation="MKVLQCKLKQPTAHYRDPKVFQNEYISTLNLPSKTTIMGMITYL
                     CDRRLNSDIDIGIIGTHHHRELEFSRGENIDFWNEYTNMRKGKDKEKFLLQGNYYDYY
                     KEHKAQNSILNYEVLKEVELTIFISCKDDEELEFIKKKLESPCKYANLGRKEDFVIPS
                     EKGCFVKEVELKEVMPMNTRDAIKENIKLKNTYVRVDLRDKENVETIINQGVLIALPY
                     KYKDLEANRDDRVYEFCHYIYVDNDGIYPKNIKVNVCNVCIDTKEVFTWL"
     gene            complement(63965..64978)
                     /locus_tag="JAM15_02550"
     CDS             complement(63965..64978)
                     /locus_tag="JAM15_02550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein
                     Cas7/Cst2/DevR"
                     /protein_id="HAT6797155.1"
                     /translation="MNEKRVKGVTLTILTESPVPLSYDQGYGNYTPIKKEQYREKIHA
                     KTSIATITYDLRRMLHQEYGWNLSNIIFGKKGNIYPSIKQNVGCVDENGLETDVFGYL
                     IPLKDKGSISKASPLRIIPFRSLNSYRGSTQLITNRGFLSSEFGRKYYDEKEENEVLR
                     DENFPTSQALAIEETLSDYYVYTITLELDRIGVVEVEDGKLLLPEERKFMSKELREKA
                     VKDILDAITVFTRNIKHSSVLLKPLAVMGGAFDKVVPFFWDDVDYNADSGEINLEGVI
                     ETIESYSLKESNTILAINDKLKISNKKELNKFNLSKYPVKEIKNLADRLEIGEDNMWY
                     LKE"
     gene            complement(64998..66464)
                     /locus_tag="JAM15_02555"
     CDS             complement(64998..66464)
                     /locus_tag="JAM15_02555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797156.1"
                     /translation="MREIKAKFYRSGDIVRDIGIVYFYELLMDLKNELEKNDYKLKFT
                     CELNRNYLSLESAEYIDHKYISDYILENQLFKVFKNGKKETLEKIFSNIDNLTYVNFI
                     EELDKSSATEKQKEGIKKDFKNRRFPYVRNSGKYGLNTSLENMETNVKRIVDTVIKSN
                     IEIDKLDLTQYEEKDSVCNVCNINKTTKLDIDLRERKDSKYNFLFRGAEKSGFKISGQ
                     VESNICFECEFFNLMCLLYINLKRPMVFAYTNDLRELAFLNHKIMLKRKMYSDKSFYK
                     KLLHEKISSIRLYRFDIDTNKGIILKFDSIIEYKELLKKIELIDIIDNYNFSREPGNT
                     RNLGKKMIDNGNLSNLKELLLDNISVLKKSTGTSREMDFVSSSYNIGLYIKLCWIVDG
                     GEEYKMKNYMESNLIYSRVGKDLFNKMTDESRRKNFSMKVIQLLKSNDRTQLFQTIMH
                     VLVSNGILIGEGFVEGLMQSSELELNTNVGLFIQEIMK"
     gene            complement(66469..67206)
                     /gene="cas6"
                     /locus_tag="JAM15_02560"
     CDS             complement(66469..67206)
                     /gene="cas6"
                     /locus_tag="JAM15_02560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HAT6797157.1"
                     /translation="MSRISIFMESCNGKFPNENSMLSVSFIKNILNAENKDFAKNIFN
                     YGEERKNNKQIKDINTAIYIPNLIRSKNELLVDGDIIFNISFYNYSMFSKLYNGILKV
                     KELEYKGYRFKIKNIKIHKEHEIKENGVIFKTMSPIIVKNKEGKYLDVEDSNYIECLN
                     YIANLTLESIRGSGLRKPLEFIPLNFKKRVLKEKIRGFKVREYYYINAYAGTFFLKGD
                     MEDLNALYKMGIGYRRTENAGMVDILK"
     gene            67465..68574
                     /gene="ugpC"
                     /locus_tag="JAM15_02565"
     CDS             67465..68574
                     /gene="ugpC"
                     /locus_tag="JAM15_02565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HAT6797158.1"
                     /translation="MSEVILKNISKLYSNGFNAVKNINIDIKDKEFIVLVGPSGCGKS
                     TTLRMIAGLEEISEGELYIGDKLVNDIEPKDRDIAMVFQNYALYPHLSVYENMAFALK
                     LRKLPKDEIDKKVKEAAKILDLLPLLNKKPKTLSGGQRQRVALGRAIVRNPKVFLMDE
                     PLSNLDAKLRTAMRTEITKLHQQLGTTFIYVTHDQVEAMTMADRIVVMKDGVVQQIAT
                     PQDVYDYPANIFVAGFIGAPQMNFIDVILIEENDEIYAQNEHIKLKLNKEKHYDLIKD
                     NYINNEVVIGIRPEDIHIEDTFIKSNPDTCFKSRIEIKELMGAETYAHLKLGENTITI
                     RFDSKNRINVGDDLTLSVDNSRVHIFDKETTLAIR"
     gene            68604..69371
                     /locus_tag="JAM15_02570"
     CDS             68604..69371
                     /locus_tag="JAM15_02570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HAT6797159.1"
                     /translation="MEELKDFLERQLNKKINIYPYENQKLDASSHLVTFNNAIYVIDF
                     LDKNNLDNLKGNFYLIYQSHIDFEYLKNIFYNLFEDINIIQHNGFFIVNSKYNLDINV
                     TTQNIIETETYQSTYIFYLGKLDSKADFDFRLQLCSDLLPHIIKDNAENKFLNLFDLI
                     RYKTLDLINEDNILNKLIDFNKIKSIDEELLYTGIKFINNDLNISKTSTSMFLHRNTL
                     VYRLEKINEILGFDLKNFENAMIFYLSVKSYFLYKKI"
     gene            complement(69559..70932)
                     /locus_tag="JAM15_02575"
     CDS             complement(69559..70932)
                     /locus_tag="JAM15_02575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAT6797160.1"
                     /translation="MGKTNARRTLFLIAIGSGTMLNPLNSSMISLALHSIQNDFHISF
                     TTVSWIVSAFYLASAIAQPVSGKIGDLMGRKVLFLSGLMLVILSASIVPLVQSFFILI
                     FIRVIQAIGTSTLYPSGVALIQNNIKERQSSALAVLTIFASTTAGLGPTLGGLLLDLG
                     GWHAIFLVNIPVVLVSICLGYFLFPKEVKEKKSIKETLKNVLSRLDIIGILLFSIAMI
                     FILLFLLSMKESFNLEQLVFGIILMCLFIWHELRTKLPFIDIKLFVSNPKLSKVYLQF
                     IILNFFNYILFFGLPSYFQDALHYSAKSTGLFMLFMSGIGIFISPLTGKWIDKSGTRF
                     PLVTSSIFMFISAVLLSVVFIHIPVIGKGIILSLAGISYGVGNVALQSSMFEESPRDS
                     IGTASGLFQTSRYLGSILATVLLGMVFEVNITSEQFQILGYVMVVLGTISFLLNFILK
                     KELRKVE"
     gene            complement(70968..71903)
                     /locus_tag="JAM15_02580"
     CDS             complement(70968..71903)
                     /locus_tag="JAM15_02580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAT6797161.1"
                     /translation="MYYIGVDIGGTGIQAGVVDNYGKIIFRSECKTVIEKGFEGILND
                     IKIMIYKLLEDNKLTMSDIKSIGFGVPGFINKEGLVTCVNLKWNKKAFNKELKRRFPD
                     VEIHGENDATVAALGEAKFGSMKGANVGVLYTLGTGVGGGIVINQKVFSGAHGLGSEI
                     GHQIIGENYFNCNCGNNGCVETFCSATAIIKYSQKLIEEGEKSRILDLAEGNLENVNA
                     KMVFDAYRENDLVAIKVINRFKEYLAKTFANTINSLDPEIISIGGGISKSSDIILDGI
                     EDLVRKFVLYKTEDIATITCATLGSDAGIIGAAFL"
BASE COUNT        23613 a        12638 c         8042 g        27645 t
ORIGIN      
        1 acttttatag tactatattg aataaaatta actttgaaat tatttacatt aaaataaatc
       61 aaatacaaat gccataaatt aagtgtttct agttagcata aaaatactta taaagtatac
      121 tcaaatattt caaataaata cttttattca aataaatctc tacttatata agtgcttata
      181 taaataaaaa gatgaactat agtaaatata gttcatcttt tttataatag tatttattta
      241 aaattaatat ttatttagtt agtagcatct acttagatat cagataagaa agcacagtca
      301 tttacttata ataagttctt ttcatatatt ttttattata attattcttt tacaagaact
      361 tttataattt ctgaaatgta catagtatgg tagtctttct ctggatacca ttttttatca
      421 ttttctttag catcaaagtt ttctggtggc atattaccat gatatagctt tttacatact
      481 ataatcatat tagcttcttc aaaagctacc gtatcatcca caaaatatgg tgtaagtcct
      541 gctttttcta ttttatttat atctctacca gaaatagtac cacaaatatt taaagcctct
      601 ctatacgttt catcaaagaa ggcaactgta aatgtatcat tactatctac aaattctttt
      661 gtatatctct gtggtcttat gtaagttgta acaacatttt taccccaata gactccaaca
      721 ccaccccagc tagcagtcat tgtgttaaac ttttctgaat caccagctgt tataagtaac
      781 cattctttgc caatcttagt aaatggatta aactgtagtt cctcaatttt tacttctcta
      841 aaacccatga cttcatccta cccttcattt tttaattata taaattaatt gttaaaaatt
      901 tgaatatatg tactcttata atactgactt ttgattgtcc tacataattc atgtaaatta
      961 taatacaaca aatcaattac tttcgcaata agtagttttc atattttata agtgtaaaat
     1021 atagataaaa tatattgatt ataaagtata taatatattt ttaaacctaa agcaatatac
     1081 aataaaaaaa tgtagaaagt aagtatctct ctacattttt tattgtatat tatttttata
     1141 ttaatttaat tttatcttga ttcagtttta taaaaaattg ttataattgt caagttctac
     1201 tctattattt gtaatttctt atatcttatt aacaacattt aagttattac atttatttat
     1261 atatattttt tcattatcta agtcttcatc aaacattttt attatatttt ttatctcatg
     1321 cttgtactca tcttcattca ttctataaag cattaaatct tctaatacat ctttcatgtc
     1381 gaagtacaca tcttctaata aataaaaata gccttcctct atatctttca atttatctat
     1441 agtatccatt tttttactta tatctttcat aatttctaaa ttttgtatat ttacatctat
     1501 gattgttaat aagtacattc tcacagtttt tattatttca acagaaaaat ctacaatatt
     1561 ataatttcct tcttttttat ataatgactc cttaaatttg ttaaaacaat tatctaaatt
     1621 agaatttata tcgttaaatg gtggtcttat tatgtcacgt attattaaaa gattttgtat
     1681 atctacatta tttgtgattg cctcatccaa aataaataaa ttatatgcat catttaatgg
     1741 gtcatgggca tctccactaa actctaagtt aacaaattca agtaaatttt tcaatgatat
     1801 atagttcata catctcatac cacaatttat atatttttct tttatatcta caaataaatc
     1861 tctaatatta tttacaaacc ttggatggtt atttttttta gcacttctca tatctgtgtt
     1921 attgaaacat gtcaaatcca aattaccaaa agtatatatt cctttaatat cagaaaatat
     1981 gccaagccat tttttaaatt ttctcatgac ctcttcataa cttggtgcac tcttcaattc
     2041 ttcagaagat atatgtgtta attcttgtat atgaggatat aactcctcat tacttactgg
     2101 tcttattaaa gatttaaatt tatcaatatt ttttgttttt tcatcataca taactgctcc
     2161 gattgcaatt atatcagaat taaatactgc tctttttgat ttagaatttg gcatattcat
     2221 ttcaaaatct atatatactc ttttcaatat aaacaccctt tccaattgtt tatagtgatt
     2281 ctttttaact atttttattc aaaattttct aagaaagaat gtttctcccc atctttttgc
     2341 caaccaagta ctgaatcaag atttacattt tctgctgcct taaatataga tttttctaca
     2401 tttttaaaat ttgattctaa gctctttatt aagtctttta tctcatatct tttattacct
     2461 gtttttttag cagcaaccat acatgcacaa tttaatggcc atataccact attttgaata
     2521 aatcttataa tatgttcttc tcttatataa taaagtggtc ttataatttt tataccttca
     2581 aaattagtag aattaagttt aggaagcatt gttttaaaat ttccagcaca caataagtta
     2641 agcattgttg tctctattac atcatcataa tgatgaccta atgcaagttt gttacaccct
     2701 aattcttctg cctttgaata taatgctccc ctcctcattc ttgcacacat atagcatgga
     2761 taatcttttg ctatttcatc tgctatctca aatattcttg aatcaaataa atgtattggt
     2821 atatttagat actcacaatt atctataagt aattgtctta tatttgcatg gtatccaggg
     2881 tccatagcaa taaattcaac atcaaaatta acttgtccat gtttttttaa ctcttgaaac
     2941 attttagcca taagaatact gtcttttcca ccagaaatcg ctacagctat cttatcccct
     3001 tcttcaacca atttataatc tcttattgcc ttcataaact tagaccataa attttttcta
     3061 tattttttta ttatactttt ttctatatct cttactggaa gtctttcctc aaaaggaact
     3121 ataatttcac agccttttcc tgatagttca ctcatctaat cacctcgtat atttatgtta
     3181 ataatatttt acaaaaaagt ctaccttcat ccacaaaata ctataatttt tactttaatt
     3241 ttactaaata atttatagtt tacaataaca cataaactta taataacata aataacctct
     3301 ttcttttatt atctttttta tttttctcat ttaatatttt attattagta acgattttta
     3361 aatgattgaa tattatacac tagatagagt tacctatcta tttacaacaa ggaggttttc
     3421 atcttggaaa ataagactag agatatcaaa aaaaattgtg gtccatcttt ggctagacca
     3481 tacattaata atcaaatttt cacagaaatg tactgccttt ctgatgcatt aaaatttgga
     3541 actatatttc cagaactaaa cttactagag tctgaaatgt acaacaaaga attatatgct
     3601 aagccaaaaa aatatagagg aggtagaaga taatgaaaga ctcatctaga gctgaactta
     3661 tgagaaaagt tcaggagaca tcttttgcat gtgttgatat gaacttatat ttagacaatc
     3721 accctgatga taaaaatgct atcaacactt ataattcatt atgtaatcaa tttgcgcaag
     3781 ctagatatgc ttacgaaaat aaatacggtc ctttaactaa ctttgggtat gctccaagta
     3841 gatgcccttg gcaatgggct gaccaacctt ggccttggga cagagaattt aattattaga
     3901 catcaagtat tggaggattg aaaattcatg tggatatatc agaaaactat acaacaccca
     3961 gttaatataa aaacttgtga ccctagaatg gctaaatttc ttataactca atttggtggg
     4021 ccaaatggag aacttgctgc atctttaaga tatttaagcc aaagatatac aatgcctact
     4081 ggtaatatgc gtgcactttt aacagatatt ggtacagaag aactagctca cgttgagctt
     4141 atatgtacta tggtttatca gttaacttct gatgcaagcc cagaagagtt aaaagctgca
     4201 ggtcttggtt caaactatgc tcaaaatgga tatggaattt atccaacaga ttcaaatggt
     4261 gttccatttg atgtaagacc tatagcagtt atgtcaaatc ccgtaaccga cttacatgag
     4321 gatatggcag ctgaacaaaa agcacttgca acttattatc aacttataaa cctaacagat
     4381 gacgttgatg ttatagatgt attaaaattc ttaggtcaaa gagaaataat tcactatcaa
     4441 agatttggtg aagctttaat ggatgcttac gagttagaag aatctcaaaa aatgttctaa
     4501 aatttttatt tgtataacta ttattatttg ataatttata atttactgtt gtgttaaaat
     4561 ttataaaaaa tataaatata atttattttc tataaacaga gaaaataaat aaaaagcagg
     4621 tatcaatcaa atagtaacat gtattatact atacattact atcaatattg tacctgcttt
     4681 catattataa gcaataaaga aaaatctatt tattaggttt tataataaaa caattataaa
     4741 actcttcttg catttacata tctacttgaa tagtagctac tatttatatt agatattgtt
     4801 actttttttg atgaacctga agatgcatgt atcatatctc catttcctat gtatattcca
     4861 acatgactta cagaaccatt atttgaacct tgtgtatcaa agaatactaa atctccactt
     4921 ctaaggtctc ctctatttac atatgttcca tacttacttt ggtctctaga tactcttggt
     4981 atactaactc ctgcagattt tttcataacg tactgtgtga atccagaaca gtcaaaacta
     5041 tttggacctt ctgctcccca tacatatggt tttccaagta gtgtctttgc aaaacttatt
     5101 acactatcag ctccttgact tggagaatta gtcgaataag atggaattga agtatcaaca
     5161 gaaccttttt cagcaaggta ttgacttgac acatatccag tttgattgcc ataacttact
     5221 tttgtccatc ctccactttc agaaatactt ccaacctcag taccataact taatgtagct
     5281 attttagaat gacttgtacc tggtcctgtt ctaacgttca atgactttgc tgttacaacc
     5341 tttgtaccct ttacaaggtc atttgaactg ttttcaacat tttcatttgt agagtcattt
     5401 acactagttc ctaaatattt acttgaaaca taacctactc taccattaga acttattttt
     5461 gaccatccat ttgactcaga tatgtatccg acttcagtcc catatcctag tgttgatatt
     5521 ttagaactac ttgtacttgg tcctgttcta aaatttaatc cttttgctgt tacaactttt
     5581 gtcgacttaa ctgaagtatc actactttca ttgctacttc caaggctatt tattgctaca
     5641 taatttccat gcacataacc tgtgtttcca ttatatttaa cttttaccca agaaccttct
     5701 tttcctacgt actcaacttt atcacctttg taaagtttcc ccattgattc atggtttgta
     5761 cctggtcctt ttctaaaatt taccgcattc cctgttattg ttctgctttc tatactcaca
     5821 ctctctactt cagactcatt agcatatgct aaattcccca tagtaggcat tattatcgca
     5881 gttgccatta tactggctgc tattctcttt tgattaaaat tcataacttt ccactcatct
     5941 cctcttttct actatcttta tttcacttca aaatataaaa gaaataattg acactattaa
     6001 aatatcaatt atttctttta tattaatatt attacaaatt tgtaactatt tgtctatagt
     6061 aatatttgct taccataaat taccatgtat aaattttaat cttcaatagc ctgtaattta
     6121 gtaatatagc catcttttac cttttttaaa aatggctata ttttttaact tttttgtaac
     6181 tttttaaaat ccagttgagc caaacccacc ttttcctctt tcggagtcac ttaattcttt
     6241 tacttcttct atgttaatat catagatagg ttttactatc atttgagcaa ttttcatatg
     6301 cttttcaacc ttaaaatcat ttttcccatg atttattaat ataattttaa gctctcctct
     6361 gtatccttcg tcaatagttc ctggtgtatt taatacagta acagaatgct ttaaggcaag
     6421 cccacttcta ggtcttacct gcgcttctgt catagtagga agctctatac atatcccagt
     6481 tttgataagt ttagtctctc caggaggtat tacaacctct tctatagaat acaaatccat
     6541 accagcatca cctttgtgag caaaattagg tattatagca tcatcattta atttttttac
     6601 ttttaaattg tacatcttat atctcctttc aactttctat aaatattata acttaaattt
     6661 cgacctcttg aagtttttta tttttttgtg gtaatataat tattagtgtt ttaaaggagg
     6721 attttttatg aaacttgtac ttgctgagaa accatctgta gcaaaaacta tagcatcatt
     6781 tttaggtgca aagaccagac aagatggtta ctttgaagga aatgattata taattactta
     6841 tgcagttgga cacttagtat cattatatga tatgaaggat tatgataaag ataaatactc
     6901 tggctcttgg aaaatgaaca atttcccatt tgttcctgag gataagttta aatttaagat
     6961 tgatagttct aaaactaaac aattcaacac tgtaaaaaag cttttgaata gaaaagatgt
     7021 agaatatgta ataaatgcca ctgacaatga ccgagaagga gaacttatag catttttaat
     7081 atttttactg gcaaaaaata aaaaaccagt aaaaagaatc ttggtaaatg aatggacacc
     7141 agaagatatt acaagaggta taaaaaacct aaaagatgaa gatgaaatga gaaatcttca
     7201 agctgctgga tatactaggc ttattactga ctggttgatt ggaataaatt tcacttctgt
     7261 tgctacattg aaatatggaa atggaaaact attaaacata ggtagggtaa ttcttccaac
     7321 agttaaatta gtctatgata gagatatgga aatactaaac tttgttccta aaacttatta
     7381 tgaaatagaa gggcatttta aagctgaagc tggtgaatat aaaggtaaat atgttaaggg
     7441 taaagaaagt aaatttgata cacttgaaga tgcaaataaa attatagctt caattacatc
     7501 tgaaactggt aaaatactag ataaaaaagt tactatgtca aaggaatatg caccaaaact
     7561 ttttagtttg acatcacttc aaggatatat aacttctaag tattccaatt ttacatctga
     7621 taaggtttta aatgtctgtc aatctctcta tgagggtaat ggtaagggtg gatacataac
     7681 ttaccctaga actgattcca ttttcttaga agaaagtttg gcttcaaaag cttctcaaac
     7741 tttagataaa ttaaaggttg gtcttgaata tgaaaataaa attaaatttt ctaaaactaa
     7801 aagagttttt gattcttcta aagtagactc ccatagtgct ataattccaa cttatataat
     7861 tccaaaaagt ttatctaagg atgaacaatt agtttatgat gccataaaag atagatttgt
     7921 agcaaacttt atgcctcctg ctgaatatga gaatacagaa attaagactg aagtagataa
     7981 ttgtactttc ttaacaaaag gtaaggtgct taaatcaaaa ggataccttg aggtatataa
     8041 taaggaagaa aaaaacgatt tacttccact tgtaaataaa gatgatgttg tagatgtgtt
     8101 agaaataaaa ccattaacta agcaaactac tccacctaaa ccatatactg aggacaccct
     8161 tttaaaggct atgaaaaatt gtggtaaaaa tgtgcctgaa gaagatacaa cagtgctatc
     8221 tggatattcg attggaacat cagccacacg tgctgatgtg ttaaagaaga taagtcaagt
     8281 gggctatgta aagaaaaaag ggaaatctta ttctataaca gaccttggga aaaatttagt
     8341 tgaaattttt cctgttaaag acttatttga tgtagattat actggaaaac ttgaaaaaag
     8401 tttaagcgat attcaaaaag gaaagtatac aagaaaagaa tatcttacta atatcattag
     8461 ttttatatat caaaatgtca atattataaa acaagatgct tcaaaaaata taaacacaga
     8521 agcatatact ttcgattcaa aaactaaaaa atttactaaa acaaaagaaa aaaaacagaa
     8581 aaaagatgta actaatactg aaaaagaagt tgctatatca aaagattcta ataacaaaaa
     8641 agaagttaaa aatggtgatg aaaatcaatc tcttggcaaa tgccccattt gtcaaggtga
     8701 tgtactagaa tttgacaaag gctttgcttg taaaaatcat aaagaatgta aatttgttat
     8761 ttggaaaaat gataagtatt taagtcttta taaaaagaaa gttaacaaaa caatggtcaa
     8821 aaatatttta aaaaaaggtg aaactaaagt aaaatcttta actgctaaaa acggtaataa
     8881 atttgatgct acattaaaat atgataaaaa tccagatacc ggctatttca attggaaaat
     8941 agagtttgac aactaaatat tcataagaaa agaaatagca gtagtataat aatctatatt
     9001 atattactgc tatttctttt cttatgaagt tttaactttt ttaatagtga cttttacaat
     9061 cacactctaa cctaatttct ttactatttc tgataacttt aatgtatgtt catctaataa
     9121 agttagttcc tcttcagaaa gattagataa tttttttact agagattctt tgagaatagc
     9181 ttttactgca tcaaataatt taaatgcttt atctgttaat tcaaccctaa gaatccttct
     9241 atcttttggg tcaggaaatt tattgactaa accatgttcc actaatctgt caataatcgg
     9301 agtcatattt gattttaaaa ttcctaaatt agaagctatt tgagaaattg atgatgaatt
     9361 tgatgtcata agataaagaa ttaccttagc atgtgatgga gccattggac attcttcaaa
     9421 ataagctttc attatatcag agttattttg aaactttttt aacaaatcgc tttctttaaa
     9481 tatattattt tcaagcacaa ataaaaaatc taaaaaagag tccgctattt taagtatatt
     9541 gttgttatcc atatttgtaa catcccttca atagataata taataaaaca ttgttgttta
     9601 atatagtata aattataaac tattaataaa tttaaaacaa gaaaaagtta ttgactcata
     9661 ataattataa atttataatc aaattagaga attataaatt gccaataaag ggaagttttt
     9721 taattagtct aaaactaaac ttaaattata agacacttta aattctacaa caagctagtg
     9781 tgcaatatat aataggagga gatatgaaaa gatatttaat agttttctta atgtgtagtt
     9841 cactgttttt agttggatgt ggaaaaacag aagaatctga acctgagaaa ccaatagcag
     9901 tttctgttca aaaagcagta ggtggagaaa ttgaaaacac aaattctttc tcaggaacta
     9961 caaaggttaa agatgaaaca gctgttactg cacagactgt tggcacagtt caagaagtgt
    10021 atgtaaaact tgggcaaaat gtaagaaaag gagatgaatt attgagtata agcagtccag
    10081 agctagaaaa tagtgtaaag caaagtaaag cctcactaga tttagcaaaa gcaagttatt
    10141 caagtgccac tggtggttca ttagaggcac aagtaaatca ggcaaaaaca gctcttgaca
    10201 atgcaaagat tcaatatgag gagtctcaaa gaaattatga caataataag attctttatg
    10261 aacaggaagt cattagttta gaccaattta aaaaaataga gttttcttta gagcaaacaa
    10321 aacaacagtt agattctgct caaagagcat acgatacagc aacttcaaaa agtatacctc
    10381 aagctaaagc acttgctaaa aaacagcttg accaagctca agtatcatat aatttagcaa
    10441 tgagtaattt agacaaatta acattaacat ctccagtaga tggtacaata acagctaaaa
    10501 actttgattc aaaggaaatg ataacacaat cacaaccagc ttttattatt tctaatccta
    10561 atatactaga agttgattta aatgtagcag aatcagatat aggtaaattt aagaaagatg
    10621 gaaatgtaga tgttataatt gaagaccaaa ggattttagg aaaaatagat tatgtacctt
    10681 cagtagttga ccctcagaca tctttatatc ctgttaaagt acttgtaaat aatacaaaca
    10741 acaaatttaa ggcaggtatg tctgcacaag taaacttaag tattgaaaaa gaaaatggtg
    10801 ctgttacagt gcctaaaaaa gcaatatttg aagaaaatgg taaaaaatat gtatacatag
    10861 caacaaaaga caatatagca aagaaacact tggttcaaac tggaattgta acagaggata
    10921 aaatagaaat taaaagtggt gtaagtgata aagatacagt gattattgga ggaataagtc
    10981 ttatttctga cggaactaag atatttcctg tagaaaagga gaagtagact atgaatttaa
    11041 cacagacttc cgttaaacgt cctctcacaa tcataatggt ctttttagta ttaatagttt
    11101 ttggtggtat tggatataaa aaaatgtcaa taaatctaat gcctgatata gaaataccag
    11161 ttgtaatggt catgactact tggacaggtg ctggtcctca agacgttgat gaacaagtta
    11221 gtcaaaaagt tgatgaaagt ttatctgccg tttcaaatgt aaaatccact atatcaagtt
    11281 cacaagaaag tgtttctatg gtagttgctc agtttgaatt tggaactaat ttggatgaaa
    11341 taatgaatga tgttaggtct aaagttgatg cattacagac cagcctccca gatgatgcag
    11401 caaaaccaac agttttaaag ctggatatga atgcacaggc tataggtcaa cttgtcatat
    11461 ctggaggaaa tgaaaatagt tcacaagcct taagaaaata cgctgaagat gtaattcaac
    11521 ctaaaataga atccatagat ggcgttactt cagcagacct taaaggtgga aaaaaagcac
    11581 aggttaatgt aatagctgac ccagctgttc tttcaaatta tggagttagt ttatcctcta
    11641 taaaaggtgt cttatcctct agtaataaaa cattccctta tggttcaatt actcaaggtg
    11701 aggataaaat agttttaaga gcaattgata aattagaatc cctagatgat ataaaacaga
    11761 ttcaaattcc tgtaaaagga ggaaatacag ttagattaga taatctttgt agtgtagatt
    11821 atggatatgc agacaaagat agtatttata gatacaatgg aaaagacagt ttggtaatag
    11881 atatttctaa acaacaagat gccaacactg taaaagttat gcagagtgca tacaaatacg
    11941 tagatgaatt gaataaggaa aatcctcaat ttaaaattaa aattgctaat gatacaagtt
    12001 catacataag tgaatcaata aacagtgtaa tgagcaactt gcttataagt gctgttattg
    12061 catttattgt aatatttgct ttcctaaaaa gtgtaagagc ttcactagtt gttgcagttg
    12121 caataccaat ttctataata ggtgctatag caattctcta ctttactggt gaaagtttaa
    12181 atcttattac tgcaagttca ttggtaattt cagttggtat ggttgttgat aatgctacag
    12241 ttgtaattga aaatatattt aaatatagga aaagtggcag attgagtctt gatgattgtg
    12301 ctattgaggg aacaagaact gtaacaaatg caatacttgc atcaacattg accacgatag
    12361 caatattctt acctatcatg tttacagaag gtatagctaa aataactttt ggggcattag
    12421 gtaaaacact aatagcttca ctagcattct cctttatagg tgcaattaca ctcgttccta
    12481 gtgtatttgc aaaattaagc agaggaaaaa atagtcaaaa gatgcaagaa aaagatagtc
    12541 ctatatttga taaggtaagt gaagcatata aaaaattatt aagtgtatgt ttaagacatc
    12601 aacgcttagt tgtaatatca agtttactta tttttgtagc ttccttattt ggaatgggat
    12661 ttataggtat ggactttatg cctgcagcag acaagggtga attatctatt tctatagaac
    12721 ttccaaaagg tcttagccta gaatccaatg attactatgt atctatgact gagaaaaaag
    12781 tctcagatat tccagaaatt aaaactttaa taacaacttt gacatcagat tcaaataata
    12841 gtaaagcaag tatagcaatt gaattagaat ctcaaaaaaa tagaaaaaga actactgatg
    12901 aaatagaaaa agagataatt gatagagtgg ctactgtacc agattgtaaa ataaatgtaa
    12961 gtcaaaacag tagtgttatg ggtggagctg gaggagcaga cttcacatta gaaatgaaag
    13021 gtcctgattt agatgtatta aaaatactgg gaaaagaagc tgaaaaagaa tttagctcta
    13081 taaaaggatt tagaaatgtt gaaacttctc ttacagatac aacacaagaa gctcaattta
    13141 ctatagataa acataaggct caagaatatg gtgtaaatac tgctgaaatt gcaggcatgt
    13201 tacgtacagc aataaatggt gactccgtaa ccactgctac tattgatgat tacaaagtgg
    13261 atgtaaacct aaaatttaaa gcagatacta ttgatagctt agaagatata aagcaactaa
    13321 aagtaaactc tgcaactgga aaagaagttc ctcttggtgc tttttcagat ataaaaatgg
    13381 cagatggtct acaatctata tctaggactg atggagattt ttctgtaaat ataactgcta
    13441 cacttgacaa tttagatgct ggtactgcta caaaactagc actagaaaaa acgaataaaa
    13501 tggtaattcc taaagattac tctataggtg ttggtggtga aacagaaatg atgaatgaat
    13561 ctatgacaag tcttggattt tcaatggtca tagctatagc attagtttat atggtaatgg
    13621 tagctcagtt tgaatcattt agtaaaccat ttataatcat gttctgtgtt ccatttgcat
    13681 tcgttggagt tgtgctttcg cttctagtta gtggtcaaag tttaagtact gtcggtatgc
    13741 taggtataat cttacttatc ggtattgttg ttaataatgg tatagttctt attgactaca
    13801 tagagcaact tagaaaaaca aatcgtaaca atgatttaat tggtttggtt tcaattggtt
    13861 gtgcagcaag attaagacca gtcttaatga ctacagcaac aacaatttta ggtatgttgc
    13921 caacagcact atctcttggt gaaggtggag aaactatgca accactagcc atagttataa
    13981 tgggtggtct aactgtatct acacttataa ctttggtgct tatacctact atatacttaa
    14041 tatttgataa atgggaaaat aagttttcag acaaaatgcc taaaatattt ggtaagataa
    14101 cagataaaat aggaagtata aaacgtaaaa taataaagaa accaaaattg aaagctaaag
    14161 tttaaataga atggagggtg attgtattga ataaaaaaat gagcaaaata gttgcaattg
    14221 gctgtggtgt tggtataata actgccaatt taatcccagt ttacgcagat aataatactt
    14281 cttctataaa caaagttgat aattctattt taagtgactc aaataaaaga acatctgaaa
    14341 aggaaatttt gactgctaga gaagctgtta gtgctgcact taaaaatagt gaaaaattaa
    14401 aaatgaaatc agaagaaata aaaatgttaa aagaaaagtt agaagtacaa gatgagtttg
    14461 atagttttac tggaagtgac aactcgtttc catacgacca aattggactt cttaaaaatc
    14521 aaagtgaaca ggctaaaggc tttatggagg accaaatagc aaatgatatt actaataaat
    14581 ttaacgattt agtttcaaga gaaaatgagc tagataagat aaaaaacaat cttgaaataa
    14641 aaactaaaga aattaaagat atgaaattaa aaaaagattt agggttagta acatctttag
    14701 aaactgaatc agctgaactt gaacttcaaa cactacaaaa tactcaaaaa gctaaacttc
    14761 aagaactaaa aaacaatcaa gactatttta agttattgac taatatagat ttaaataatt
    14821 atcaattgga taaagaatat agatttgaat cttttagagt aggtggctca gttgattcat
    14881 atatggaagg taaggttaat gaatatttaa aatacgacca attgatttta gaacgtacag
    14941 aagaaagctt taatgataaa gatgagaaca aagcagattt accagataga cctgaattaa
    15001 aaaaacccac tgtgcctcct aaaccaatta aaccatcttt agataaattt tctactcaag
    15061 aagaatatat aaaggcactt gatgagtata ataaaaaact tgatgaatat gaaagtgcga
    15121 ttaatgctct taatcaatat aatgctgaaa agactaatta tgctactggc cttactactt
    15181 atgcaaatta tcttcaacaa aaatttaata ccgaaaatgg tctagtaaca ttagaagaca
    15241 gtaaaaaagc tcttaaaaaa gggttaattg atagctatgc tcaattactt gctttagaag
    15301 atacaattca gattactaaa aaacaacttg atttatcaga aaaacaatta aaaaatacta
    15361 aattaagata tgatttagga ttaattactc taactgatta taaaaaacaa gtggtaagta
    15421 atgaagatgc taaaaatagc tatgacactc ttattgtgaa ttataactca ctaaaaaatg
    15481 gtatagaaaa accttggata cttaataatg gaaagtaatt ctggtaaata gaaagattac
    15541 tttaaaatac gtttgattaa aaaatagtta tgcacactcg tggctttagt catggaagat
    15601 tcagaaggca aataatagaa atagattagt aaaaacatat ttacttataa aactgtatac
    15661 ttttatagag gctatctcaa aatagagata agcctctttt ttattgttta aattataaaa
    15721 atatatttga ttccatacaa aaagagtgcc ttatgaacta aaaagttcat tttgagacac
    15781 cctcaaaagc ttaactctaa atttaattat tttttatcaa atgtctcatc tattttacat
    15841 cttaccatgt taacaaattc agaaatatta tatcctctaa gtttgcatcc acatttagga
    15901 caataatcca gtttcctaga taccaaagcc ctacaactag gttctggaca tcttattttt
    15961 agactctcat ctgctacttt aaatccacat cgtgggcata tactacctgg acgtgatgat
    16021 acttcctttc cacatttagg acactttgtc aactttatcc cctccagtaa actcaattta
    16081 attgatagtt gaaatttctc tctacaataa tatatgcaat ataattaaat acgtttcact
    16141 tacaactgta taagttaaat ttttataata aaaatcccct atattcaatt tacaaatact
    16201 taatttgata cattgaacaa taggggattt tatttttatt tagttacata ttttgcagtc
    16261 tattattatc taggattttt tatagatgct tgagctgctg caagtctagc aattggcact
    16321 ctaaatggtg aacaagatac atagttaagt cctacactat aacagaactc tactgaagat
    16381 ggttctcctc catgctctcc acatattcct agttttaatt ctggtttaac ttctctacct
    16441 aatttagctc ccatcttaac taacttacca acaccatttt ggtctagtac ttggaatggg
    16501 tctttttcta atatttcttc atctacatat tgacctaaga atttaccagc atcatctctt
    16561 gaatatccaa atgccatttg agttaagtca ttagtaccaa aactgaagaa gtctgcttct
    16621 tgtgctattt catcagcagt taaacaagct ctaggtattt ctatcatagt acctacagta
    16681 taaggaactt ctataccttc ttcttttatt atagcgtcaa cagtttctac tatcattttt
    16741 cttattattt ttaactcatt tacttctcca actaatggaa ccattatctc tggagaaact
    16801 ttaacacctg ctttgattgc ttctatagca ccttgtatta tagctttaga ttgcattaca
    16861 catatttcag gataagttat tgcaagtcta caacctctgt gtccaagcat tgggttaaac
    16921 tcatctaaat caactattct cttcttaata tcacttactt ttattcccat agattttgaa
    16981 agttcttcta tagtctcatc atcatgaggc aaaaattcat gtagtggtgg gtctagtaat
    17041 cttatattaa ctggttttcc atccataact ttaaataact ctacaaaatc ctctctttgc
    17101 attggtaata ttttttcaag agctttttct ctttgttcta ctgtattaga taatatcatt
    17161 tctctaactg ctggcaatct agcttcatca aagaacatat gctcagttct acatagacct
    17221 ataccttctg caccaaactc tatagctgca cgagcatctc taggattatc tgcattagtt
    17281 ctaaccatca tacatttgtg tttgtctacc cagttcatta atttttcaaa gtttccagtt
    17341 aaagatactt ctgttttctt aacatctcct aggtacacat ttcctgtaga accatctata
    17401 gaaatgtatt caccttcttt tataactaca tcatcaagtg ctcttatttc tttattaaac
    17461 tcatcaactt ttatttctcc acatccagca acacaacatt tacccatacc tctagcaaca
    17521 actgctgcat gtgatgtcat tccacctcta gctgtaagga ttccttctgc tttaaccatt
    17581 ccttctatat cttctggaga tgtctctaat ctaactaaaa ctactttttc tcctttttca
    17641 tttgctttta ctacatcatc agcattgaaa taaactttac cacttgctgc acctggtgat
    17701 gctggtaaac cttttgctat aaccttggct tcttttaatg ccttatcttc aaattttgga
    17761 tgtaataatt ggtctaattg attaggctca attctcatga tagcttcttt ttcatcaatt
    17821 attccagctt caactaaatc aaccgctaca tttattgctg ctgctgctgt tctcttacca
    17881 tttctagttt gtagtatata taatctttca ttttctatag taaactctat atcttgcata
    17941 tctttataat gaccttcaag tatatgagta atttttacaa attcatcgaa tacagctggc
    18001 attacatctg caagagttga tatattttga ggagttctta tacctgcaac aacgtcttca
    18061 ccttgtgcat tcattaaaaa ttcaccaaat aatttatttt ctcctgtagc tggatttcta
    18121 gtaaatgcaa cacctgtacc actagtttct cccatattac caaataccat tgattgaata
    18181 tttactgctg ttcctaagtt atgagctata tcattcaatt tacggtatac gattgcacga
    18241 ggattattcc atgatctaaa tacagcctct attgcaagca ttaattgctc ttttgggtct
    18301 tgtgggaaat cattttttat ttctttttta taaattgctt taaattcttt tactatttct
    18361 tttaaatcat cagttgtaag ttctgtatca actgtgtatc cttttgcttc ttttactctg
    18421 tctaatacat tttcaaattt atattttgga acttccatag caacatcaga aaacatttgt
    18481 atgaatcttc tgtagctatc atatgcaaat ctttcatttt gtgtagcctc tgctaagcca
    18541 acaacactat tgtcattaag acctaggtta agaattgtat ccatcattcc tggcatagag
    18601 aatactgcac cagaacgaac tgatactaat aatggattct tattgcatcc taatgtttta
    18661 tttaagtctt tttctaaagt agctaaatgc tcttctattt cttttattat ctctgctctt
    18721 atactttcat tgttaacata ataatcatta cacgcttctg ttgttatagt gaatccagga
    18781 gggacaggta agcctatctt agtcatttct gctaaattgg cacctttacc tcctagtaaa
    18841 gatttcatgt ctttgcttcc ttcaccaaaa ctataaacat acttagtttc cattgttaaa
    18901 tcccccatta atctttttat tttaatttat atcattttta ttaatagaca ttattaaatt
    18961 tctatttctt tgtatatctt tagaccattt tctttcatta tgtctaaaat tatacctgct
    19021 gtttcttcta ttgccttatt tgaaacgttt attactgggc atccaattct tttcattatc
    19081 tcttctgaat aatctaactc ctgaagtatt ctttctaaat tagcgtagtt tgctttactg
    19141 gacaatccta aagcttttaa tctttgggtt cttatctcat tcagcttttc aggtgaatta
    19201 gtaagaccta ttatcttttt agtatctatc tcaaacactt ctttaggaat tggtatttct
    19261 ggaactaatg gaacattagc tacttttata tttttattag ctaaatacat actcaaagga
    19321 gttttagatg ttcttgatat tcccactaaa attatgtctg cttgaagaac acctctaggg
    19381 tctttcccat catcatattt cactgcaaat tctatagctt caactctctt aaagtaagat
    19441 tcatctaatt ttctaattat accagcttct cttttaggtt ttcttcctgt tctcttgctt
    19501 atttctctta gtatatctgt cattaaatct atacaactaa gaccttctct ttcgcaatat
    19561 ctttcaacaa tactgcacaa ttcttcatca actaatgtat atacaattaa agcgttttca
    19621 gcttttgcat tctccaaagt ttcaagtagt actcctttat taatcatgta tggaaatctt
    19681 tttatttcat aagtttcatt cacataaaac tgagacatac atgcttttgc aacttgttgt
    19741 gcagtctccc ctactgaatc tgatactgca tatataatta ggtttttcac cagcatacct
    19801 ccttaattgt caactatttc taagaatagc ttagttatgt tggtttttga tattctccca
    19861 acaactctca tatgattttt gtcttctccc ttatattcaa caatcggaat cgaatctact
    19921 tcatgttcta ttatttttct tgaagctaat aaaacacttg ctcctttagt taaagtgact
    19981 acatttggag ttcttgtcat tatcatacct attggcattt tatttatatc agaacctcct
    20041 atagttgctt ttagcaagtc ttttctggaa acaactccac ataactcttc attctcatct
    20101 ataataacta tactccctac atcagataaa aacatagtga ctattacatc atatatactt
    20161 tcatccttct tagctagtac aggcatgctc attatatcct ctactgtttt ttcttttaca
    20221 cttttaccaa ttaaatttat ttcactaact cctgaataaa aatatccaac ttttggtctt
    20281 gcgtctaata ttcctgtcat tgttaatata gctaaatcag atctaagtgt agcacgagtc
    20341 acattcaagc tggaggcaat actttcactc gttattggtt cattttcctt aactatatct
    20401 ataattttta gttgtctttc attaagctga ataataatca ccttctttca ttgtgctata
    20461 ctttttatct tttcgcatct tatatagtat attatataac tatatatacc attctgtaaa
    20521 cagatttttt attgaatacg atatattttt tactaagttc tctcgcttaa agatatttat
    20581 tatatattaa tgggggatat ttctttaatt aatagaacta tattagtatt acagttaata
    20641 ttataataca taattggtca ttttaattca ttttatatta aaatttttaa taatattgtt
    20701 tcaatgtgaa tataaaattg cagaactaat tcaaaataat ttttacgact acaaataacc
    20761 tataatatac ttttaaagaa agtatcctaa caagaatata taaaaattta aaagggttga
    20821 tttaaaaata accatcaacc ctttttacta atatctattt atattaccat caaatcttac
    20881 ccaaatattt tttcttgcaa ttgtcttaaa tgatataaag tagtatcttt ttctatctct
    20941 accatatcgt aagttataac ttcacctttt ttaatatctt ttacaacttt agtcttctta
    21001 cttatcaaac caataggtac agcattcata gcctttgcta catcgtattt ttctatagta
    21061 ccatagcatg tatatgctcc atagccatcc ataaactcac cttttttcaa atctttctta
    21121 gctatagtca taacttctgc aactaatcca gctttaggca ctattgtagc tttatgttct
    21181 aaaactgcca tagctgctga taaaggagtc tctaagctac ataaatgata tggtctatat
    21241 aatatgtaat taggtccatc acccatactt aaatatttta attcatcatt aactgctttt
    21301 aatttatggg ctactactac gaaaactcca ggtgctatac catttacaaa atcaactaca
    21361 ccgtaattat ctaatactcc gccttcgctt tttaatgcat atttcttagg tacttcatta
    21421 actgtagctt caataccatg accacctctt acatcaggca caaatccagt tgcattacac
    21481 attaaagcca tttctaccat tgttttagtt ccttctttaa aagaagctat catatgaggt
    21541 gaagctcctt ttctttctgc ttcttctcta actgtatcag gattacaatc taaatctaat
    21601 ttattatttt ttcctttacc tattactcta acttcaaacc ccattgcatc tgcaaaatca
    21661 aataattcca ttactgcacc tggctcatct cctgcagaac ctgtaaatat tactccagca
    21721 tcatctgcta attttttaag tattggtcca acaacacaat cagtttcagc atttaacata
    21781 actatatgtt ttttatttaa aatagagttt aatgctatct ctgcaccaat tgcaataccc
    21841 ccagttgcat ctataactac atctattgac ttagttttac aagccacaag aaaatcatta
    21901 catgtcaata cttttccttc ttgtaatttt atttctgcat ccttttcatt tgttacatta
    21961 tctataattt cttcatctat tcctgcatca gtaaaagctt tatgagccaa ctccaaattt
    22021 atatctacaa caatagaagc ttcaatacct ttcatatttg ccatttggct taccattcca
    22081 tttcccatat gcccagctcc tataagagct acttttattt ttttaccttc ctcttccaat
    22141 tttgcaagtt ttctgtttaa atctaacata ccaattcctc ctgttataat aattttattt
    22201 tcaaattaag aaatagttat taaatctcca atagttatat ctggatttcc tatttccaca
    22261 tgtatttctc ctggtaaatt tacttcacat tttccatcaa atttgattgt acaatgccca
    22321 atttctctaa gagtcttctg agcaatatca ccaactgaaa ctatacaata atctctattc
    22381 cctatagtaa gtgtatctcc tatttcaaca tcacttttta acgttgctat cgaatgaact
    22441 acagatatat cctttaagtc gtcatcatta atggtttcat catatataat aagacaattg
    22501 ctttcatcca ttaactcttt aactaaactg cctatcccac ttatcttaac ttcatatttc
    22561 atgacattcc tcctgataat ttatatttat attgagttaa ttaaaagaaa catttatttt
    22621 ttcttttata aattttatag cttgtacaat actctcttca tctttaaatt tttgctctgc
    22681 gctatatata tctaatcctt ctatttcttc aatctcttta aatttagcca ttactgtacg
    22741 cccttttaaa atttctccaa actttataaa cccatctgaa tctgaagata taatggctat
    22801 acttccttta gaaaaatagc ttttcttttt gcctgtagac actatatcac cctttttttt
    22861 agctctattt aaagttttaa aatacaattt attctgcttc attataaata tagtatttaa
    22921 aatataagca acaaataaaa ttactaataa tttcatattt atacaccttc caaaaatcac
    22981 attattttta aatctgtata acaactataa atgctgtaca atagttatat aaggttttta
    23041 agtaacacct ttttaaattc taaaaaagtt ctacatttac ttatcttatt cgttaatttt
    23101 acatcttggc ctatctttaa aacttcttca taaattttta ctaataagtc tgagtctatc
    23161 ttattctcac atggaaacat tgtcataaga attattttta tacttctatt tgcatattct
    23221 attggttctt ctaaaattcc aactgccatt aaaaacttat ctgatttttc atttacagag
    23281 tgaggaaata ataaaccttt atcaaatact gtgggagatt tttcttctct attgactata
    23341 ttttttctaa acttatcatc aatacatccc aaatccataa gatggtccat cattttttct
    23401 aatgaagcaa gtatagtctt ttcatttaat atcataaatt tatcttcatc taacaaatta
    23461 tttattagta aatttgtaga attagtagtg tcaatattcc cttctcttag gcacaatact
    23521 gtttttaatt gttctcttaa tttgttttca tcaaatattg tatttatttt taatactatt
    23581 gtatttatat tcgatgtgtc taaatcaata gttgtaaaaa ctatatcgta ttcatctaag
    23641 ttaatatttc tcaaattaaa acttgaaaga gtatcaattt taggattatt tcctatcagt
    23701 ttttctactc ttattttcaa tagttttgct gttcctagac ctgtactaca tataattgct
    23761 atttttttta ttgaatagaa tctactgcta tttctttcta aatatccact gaaatggatt
    23821 gctatatatc caatctcatc ttctgaaact tctaagttat actttttctc tattactttt
    23881 cctgctattt gtgctaattt aaatggaagt atataatttt gcttaatctc ttctaacaaa
    23941 acatttttta actttatatt aaataatagc ctgtttaaag taaaactaag atgatatcct
    24001 agacctactc ttaattcatc ctcatttata aaaataccca tatcgacata tatttgatta
    24061 aatatatttt ccatcaactc atcaatgttt ttactaattc tactactatt taaagcacat
    24121 tctgatgctg gtgcatttcc actaactaat ggtatagtta aataaataat ttcttcatca
    24181 tttaaagtac attcaaacat tcctgatatt atatgtttta tttccctagc aataaagtat
    24241 tcatcatatg atttaagtaa atcaaacttt acatcatagt cttttacttt cttttcttct
    24301 tttactctat agactaaaac tactatgtag ttaataactt ctcttaacat ttcatctgtg
    24361 acataaaaat tattttcttt aaataaagtc aatagttttt cttctaaatt tatgatttct
    24421 tcttttttga ttcctttaaa atactttgaa ttactgaaat ctttccttga gtttttatac
    24481 aactgattta atataaacag tctaatatca agttcatttc catttaattt catacctgta
    24541 ttctgttttt taattaagtt taaattatat gaagccaaaa ctttttctac atactggaaa
    24601 tcatttacta aagtagttct tcctacacac atctcatcag ctaaactatc aagtgtaata
    24661 aatccatcta gttctatcaa gtaatttagt ataaactcta ctctatcttc ttttgaattt
    24721 aatgaaaata cattttttct attcatatca ataatcttat tgagtatctg ctcatctttt
    24781 atttctagtt tatagccttg accctttata tatttgatta ctgctatatc attacctaaa
    24841 tctttattca attgttttat atacgtcctt acacttctag ttgtgacatt caattcattt
    24901 gctattgaat taatactcac aaactctttt ttactacaca taatcaatat cttaaatatc
    24961 ttgcggtcaa tagaaggaat tttctcagtt acactcattt tgtatctcct ccttgatttc
    25021 attctagtac aaatttgaaa ccaaattaat acataaaatt tcactttaat aaaggaaaat
    25081 ttagtattaa tctaactaga taattacagc taattaatag tataaaagct agtctttcat
    25141 taacaaaaaa tcttgactag cttaaattta tatttacaat tttattaatt aattccaagc
    25201 cttatattga catcaaatat tatttcaatg caaatactgc aactccatat gcaataataa
    25261 cagctattgg cccagttatt aaacgagagt aaaataaagc cggaacacca tactctacag
    25321 tttctggttc tgcttctccc aaacttaatc ctactggtac aaaatcacat ccagcttgcc
    25381 catttattgc aaataaagct ggaagtgcta aatatgctgg tattgcacca aggccaattt
    25441 gtgtacctac aagagtccct accacttgag ctataactgc accaggtcct agtattggtg
    25501 ataagaatgg aagtgtacaa attattgata taatcaataa tccaccaata ttacctgcaa
    25561 gtggagatat aactcttgca atccaatctc ccagtccaga tgctaaaata attcccataa
    25621 gcatacttac aaatgccata aatggtatta cattattcat taccatttgg atagtatctc
    25681 taccagcatc ataaaatttt gaaactactt ttcctgctcc ttgcccaata gaaagtatta
    25741 tgttcttttt agcatattca ccttgtgctt ttgacttaac ctcatcataa ttatcaggct
    25801 ttctaataga actcttattt tcgcttttat tttcttgaga tttttgtggc atatcttccc
    25861 catctacaac acttatacag ttaggattaa catctgatac ataatattct tctgttataa
    25921 attttgctaa agggcctgtt tttccaactg gatttacatt tattgtaggt atttttttct
    25981 ttggataaac cccacatcta gcagttccac cacaatcaat aataactact gccacttctt
    26041 catcagaaac cccagtttta aatccatcta caatttcaca acccagtagt tcttttattt
    26101 taaatgttac ttcatgaata ccgccagcag tcattgataa tatcttattt ttattgcctt
    26161 ctttttttat atataaagga cctccccaac ctgaagctcc cctttctatt tttaatattt
    26221 tattttcctc cattttatct acctcctaag ccttatttgt tactttattt tttcttgtta
    26281 aaaaagcata cattctttct gttactatac ctcttataaa aattacaatt agaccaacta
    26341 taaaatacca taatgctagt gtagtagttt ctttacctaa agtagtcaaa cctgctgata
    26401 tccccaacca tacaaaaagt tctcctgcat ttgcatgtgg aaaaatacct gtaattggat
    26461 gtacaaatga aactgctgca tcataaaatc ctgctttgtg ctcttctttt aaaaatctac
    26521 caaatgtata gcacatagga tttcccaaga aaaatactga tactaatgga agtagaacat
    26581 atcttgtaaa agaatttctt cctagtttag aagcccaatt attaactctt tcttcaccaa
    26641 ttatcttaat caaagaatta attgctacca ttaatacaat taacgttgga agagtacctg
    26701 aaacaagacc tataaattgt tctccccctt tctgaaacaa accgataaac cactctgcac
    26761 ctttacttag acctgtaata acgttttcca taaaattata acctccctat aatatcttta
    26821 aatttttaat tttactgctt accattaatt ttacaaatta catctttttt ctgtactata
    26881 cgctaatatt gtaaatgttt ttttattaat attattttaa tataatattt ttgataaata
    26941 aatacatctt ttttcaattt tataaaggaa aaaattgtac taattagaat tttcagaaat
    27001 atgcaaacat tatttcgact atattctaaa ttcttcttag aaatttaaga acttattttt
    27061 atttctttta ttattaaaac tctctaaatc taataaaaat aaaaaataga tgctctttta
    27121 cgaacatctc tttcttaatc aaattatttt tagttttctt atagattatt ttaaaggtat
    27181 ataaatatca atttgcgagt tcacattatt aggacctaaa aatcgttcat catatacttc
    27241 aaaatcatct cttatatcaa gttcttcttt tgagcttaaa aaccaagtac cccatatata
    27301 ttcataagtt ttatctaaat tctctaagct accagtatga gtaaatatag catactttcc
    27361 ttccttaata gtttttgaaa caaatgaatt tggaatcaca tcataactat taacttcaaa
    27421 ccctattatc tcattaaact ccatactttc actaactagg tgtatttcag aggttgcttc
    27481 acagattcca aaaactctct ttgatggcaa agtattttgg acaatattat gtacttttct
    27541 gaacttctcc cataagtcag gtaatgaatt attttctaaa attactttat cctttatacc
    27601 tattaccttt atttcttcta tttcttttat aactggttta atcgttatat ttccaacaag
    27661 atgtctcata aaatctaatt ctaatttttt ctttttagca acaaatacat caattctatt
    27721 ttttctatat tctatagggc taaccttgta tatagattta aatgctctgc taaatgcttc
    27781 tgaagattca aatccactac taatagctat atctatcact tttttatcac tatataaaag
    27841 ttcttttgta ctacttacta atcgtctttt ttttatataa cttcctacac tctcaccaaa
    27901 catagactta aataagcgtg ttaaatgata ataagaatat ccagtttctt ttgccacatc
    27961 atttacagtt atattttcat gtaaattatt ctcaatatac attacagctt tttcaaaata
    28021 ctttaagtaa tccaatatgg cacctctctt ctacttaaac tctttaaata tgtaaaatag
    28081 cactattttt tactatacta aaatattata actaattcaa tacgataaat aaaaactttt
    28141 agttgattta tatagcctaa ttatttagaa taattaaata cattttttat tcaatgaaat
    28201 caaaaaagtc agatggtgct ttttcaatat ttatgtttat cctctgtgtt atagatttaa
    28261 tgtcattttt taaatagtag ctctcccatt tattctctag tccaccccat aaaatattaa
    28321 actttcctat atttaaatcc ataactatac tttttaaagt tccaaaaaaa tcattatagt
    28381 aattacaaga taagccattt ggatattttg aagacaataa attcattaac tctttctctc
    28441 caattttttt agacttattt atatattctt taattaattt atatctatga atagaatttt
    28501 tcattgattg tggctctaat ttatgaagtt tatcaatatg tgtatgatta gtagagtgta
    28561 aaaaatattc tcttttactt tctaaactgt tgattatatt tacttctttt ttcccatcta
    28621 aagtctccac aagtgcaatg tttccagact tatctgcaag caataaatta atattgtatg
    28681 caattggcat atcttttaaa tattctaatg cttcatctac atctttgcaa ttttctaaca
    28741 aatatctaat aacagcccaa aactgtaaac ctacaattgc tggttttctt aaaccatctg
    28801 aattgcctac aggaatacca catgatgact gacttacacc taagccacat tcattcatac
    28861 cttcacctct tccaaattgc ataacggtag tacctatatg tgcatatttt ccatttactt
    28921 tagttttaca taaaacaaaa tcctccatat tgtgtgagaa atcgaaatta cgtgcaaata
    28981 gtacatgccc attttcagtt aattctggtg ctaatgcaac ttgactacaa cctggtttaa
    29041 gataagtcat agtataatat aaaatttgat tacaattcac ttgaattgca tcagcaaaac
    29101 cttgcaattc ttcattaaga cctggacaat atttatcaaa caactctatc atctcttttt
    29161 cttctttttt gcttaccaga ttagatttat taatctgacc ttctattatc tctggcatat
    29221 tagcaaccaa ttctcctagt ctgtatccta tctcataatt tgtaccactc aattcaatat
    29281 ttcttacttc taaagtttcc atatgtaccc ctcctatata tcttataatc gattttatca
    29341 ttcgaattgt aatcattcat gatattttgt gctacaagtt aaaaaaggtt atataaaaac
    29401 agataagcct ctttttcatt gttaaaataa taaaaatata tttaatttca tacaaaaaag
    29461 agtgtctcat aaactaaaaa gttcattttg agacactctt cttattttaa agagtataat
    29521 taaaaatagt ctaagttcta ctcttccttc atttttttca ataactctgg attttcaaat
    29581 aaattaaatc ctgttaaagc taatattttt ataccatcaa ttactctatc ttttgcatat
    29641 gaatttatag aagcctccaa aaattctttt gtatgtagtt cttctccatt ttcagaaaac
    29701 ttcatcaaag gatgtataca tggcattatt tgacttaaat ttcccatatc tgttgaacct
    29761 aacattactt gttcatcttc atatattcca aattcctcca taatctttgt aaatatgtct
    29821 accaaaactt tattttcatt taatccttgg caagttggtt caaagtgata aaattcaagt
    29881 tcacatccag tggctattgc agcacctcta gcacaatttt tcactttttc tactacttca
    29941 tcaaagtaat tttgttcttt tgcccttatc tctaatctta cttttcccat atcaggtatt
    30001 acatttgcag cagttcctgc ttctagtata ataccatgta ttctcgttcc atctactaat
    30061 tgttgtctta gtgcatttat attattatat agtagtacta ctgcatctaa agcatttatt
    30121 ccgttatatg gcttagctcc tgcatgagat gcttttccag taaatatgaa atctagacct
    30181 cctattgcta taatttcagg tgttacacaa gtttttgaat ttggatgtat catcattgct
    30241 gcatcatagc catcaaatac accatgttct atcaagtaag gctttccatc tccagtttct
    30301 tcagcaggtg ttccaattat acttacttct cccttgtaag tatccagtat acttgaaaga
    30361 gctattccag ctccaactcc catagatgca attaaatgat gtccacatgc atgtccattg
    30421 cctggaagag catcatattc tgctataaat gctattttag gaccatctcc atttttcttg
    30481 gttgctttaa aagctgtagc catacctgcc aagttttcct caacatcaaa accctcttct
    30541 cttagaaatt ctgatatttt tttagcagat ttatattctt gcaaagcaat ttctggttca
    30601 tcatataaag attgacatag ccctagaatt ttttctttct ttgaatcagc cacttgtatt
    30661 attctttctt tcataccaat cttacctccc actaaattta tttagtaatt tttatatttt
    30721 attataactt taatttaact catgcttatc ctcttttaag tatctatttt cccaaaactc
    30781 agcatttctt atatctaatt ctataggatt aaaagttcta tcgctccttt ttactcccat
    30841 ctttttctgc ctttgataat cgtaatatgc ttttatagct ggttttttta gtgtaaatat
    30901 accaactaag tttatatatg ttaatacacc tatacatata tcaccaagtg cccaacttgt
    30961 aagtggttct ataaagcaac acattgctgc acatattata agcataaatc tacagacatt
    31021 aattatgtgc ttttcatgtt tttctgcctt aattctagtc actaagtaag atacgttggt
    31081 ctccatcatg tatgagaagg ctaataatgt tgtaaatgta aatagtagta aaactattgc
    31141 tataaaaata tcacctaatt gaggatgtaa tgtatttatt gcactctgta catattgtgg
    31201 acctggttct acacctggta atgttgtgta aacatctgta acattataca ttcctgttat
    31261 tataatcata atacctgtag ccatacatat taatagtgtg tctacataaa cagaaaaagc
    31321 ttggactaat ccttgtttgg ctgggtgact cacttctgct gctgctgcac cataagttcc
    31381 agaaccttct cccgcttcat ttgagtatat acctcttttt actccccaag atattgctga
    31441 acctaacatc cctccaaaaa ccgaaccaaa tccaaatgca gatttaaaca ttgtcataat
    31501 agctcctgga actagattta tatttgctat gattattacc aatgtcataa taaggtatgc
    31561 tccacccatt ataggtacta ctttctcagc aaataaacca attcttttaa ttcctccaaa
    31621 aattattata cctagtgcaa tagaagatgt aactgctatt gtcatttttg aaaatccaaa
    31681 tgcttgattc attgctagat atagagtatt tgattgtgtg ccaggcataa aaaatgtata
    31741 acttatgatt gcaaccactg aaaataaaat tgaacatttt ttccaaccaa gacctttttc
    31801 aaagtaatat ggaggacctc ctctgtactg tccatcatgc tcatctttat atatctgagc
    31861 taaagtagat tctacaaatg cagttgccga ccctaatgta gccattatgc acatccacac
    31921 taatgctcct ggccctccca ttgctatcgc tacagctaca ccagctatat ttccagttcc
    31981 tatccttcct gccatagatg tagcaaaacc ttggaacgaa gatattccaa catgagagct
    32041 atctccttca agcaaaagag taaacatttc ttttacatct tttatttgaa aaaatcttaa
    32101 tttcattgaa aaatataatc ctatacacaa acacattgca actaatacag gtgaccaaac
    32161 aattccatta atggtgttaa ctaaatcggt cacttaactc accaccattc attttatatt
    32221 tatagacaat aatttaaata gctatgtttc aacattctat ataatcttca actcaatata
    32281 tctaaaaaat ctatcttcta tttatattat ttttaatcca caagctataa gtatctatct
    32341 ctaaaacaaa gaatattaat cgatatataa acgtaaattt ataaactttt taacgatatg
    32401 tatttgacaa ataatcaaac aatataaatt ggaatacatg taatgaaaag cctgaaactg
    32461 ttactatata aatagtacca tatacaatta ttaatatata attgaatagt atatagttag
    32521 attttaaatt ttcgtattta ttatgaggtg taaaattgag tacaattacc acctattttt
    32581 gaaattcttt taatttaaat taaataggtt tatgtaaata tataaataga tgataattgc
    32641 tactcaattc cagaccttta ggggtaactt tatactaaaa cctagaaaac ttgataacat
    32701 tttggtgtgt tgcactttaa attttaagta ttgctataaa acttaataat ttggtatttt
    32761 tacaatattt atgcttctaa cttactttct cttttcttct taacttttaa tatatataaa
    32821 caagatagta taccaattat tagaattgct atctggaata taaatgtata tgtgtaacct
    32881 ttattgccat aagtatctat ccagtgtcct attaatgcaa attggaatac atctggtgaa
    32941 aatcctaaag ctgcagctat acctatagta gttgctgaat atttaactgg aacttttact
    33001 tcatcttgaa ctgcatagta tatacctttt cccatgtaac ctaatatacc tactacaaat
    33061 gttaaagcta taaagatagt cattggagta gatgcaggta gtactaggaa taaaattatt
    33121 actgctatac caaatacata tattggtagt agtacttttg taggtgattt tactttatct
    33181 gcacaatatc ctccaaatgg tgctccaaac aattttagac catgttgtct tattattgct
    33241 aatgccccag acaatgccac agaacctcca agtactgatg ttatatatgg tgtaaaataa
    33301 gacattgtaa ctgtgaatga atatacacag aatatgctta ttcctactag ccaagtgttt
    33361 ggtgatttta gtactgtcat aaaatcgcca gcagacattt tttcacttgc ttcttcttct
    33421 ttgtcttctc tgatatctac atctttaatt acaaaccata atactggaca catcactatt
    33481 gataatattc ctaaagatat cattacccat ctcataccca atacaggagt tgaaaagcat
    33541 gtataaatat ataagaatat tgctcccatt actacgccag aaactccaac catagcttca
    33601 ttgaatccat aaactttacc ttgattatct tttcctataa ctctaagtat ttttaccata
    33661 gaaggatagt tcataactaa tgatgtgatt gcacaaccta cccaagtagc aactgcaaat
    33721 ggatagttca tattaaatgc aaataaaaat gatactactc cattaagaaa tacagaacct
    33781 aaaattatct ttctataatc aaatctatct gctaaccagc ctcctatagg agctccaaat
    33841 atattaccta acccataaat tgtaagtaga aaacctagtt gagtgtttgt acattctaat
    33901 gcttttagga ttggatcata taatgtatat tggataaatg gtataatata aactaattcc
    33961 caagatattg ctataataac aagttgaaac attaactttc caaactttat accgttttct
    34021 ttttctccca tatttaaacc ctcacttttt atatttattc acaagcataa ttgagttctt
    34081 tttttataac ttctgcaagt atctcaacac ctttaacgat ttgttcttct gacattgttg
    34141 tatagttaag tctcatagta ttttttggac cattatttgc aaagaaggac tctccagaaa
    34201 cataagcaac tccagcatca atggctttat ccaataaatc atctacattt atactttcag
    34261 gaagttcaac ccatataaac attcctccat ctggttctgt atatttagct tcctctggga
    34321 aatgtttctt catagcatct aacattagca gacatctttt cttatactct gctcttattt
    34381 tttctatatg ttcatttaag ttgtatttct ttaaaaattc tattacttgt acttgcgaaa
    34441 attgatttga ctgtaaatct ataccttgtt ttaaaagttc tgccttatct atgatgtcta
    34501 cattaccaca catccaagca actctaaacc ctggacataa tacttttgaa aatgaaccta
    34561 agtataatac tttatcttta gtatcaagag atttaagtgt aggtagaggc tctggtgtaa
    34621 atcttatttc tccataagga ttatcttcta ttactatgac atcatactta ttcacgactt
    34681 ccataaaatc ttttcttctt tgtaaagacc atgtttttcc tgtaggattt tgaaatgttg
    34741 gtattacata gattaccttt atgttagaat tttcagataa taatttatct aaatcatctg
    34801 ttaccattcc ttcatcatca gtatctactc ctaaaaaatc acattcataa ggtctaaatg
    34861 catttattgc acctaagtaa cttggatttt ctgtaactac tatatctcct ttttctagta
    34921 aaatcatagc actaagagat ataccttgtt gtgagccagt agttattatg atattttctg
    34981 cttttgtatc aatattttct tcttccttca ttctttttac taataactcc aataactcat
    35041 cttcaccttt agtaggtcca tatgctaaag caaatttgcc tctttcacta agtacttttt
    35101 gagttacttc acttatctct tctattggaa ataagtttgg gtcaggaagt cctgcagcaa
    35161 aagatataac cgtaccacca cttgccacct tctgagctat tttcttttga gaagctctta
    35221 tagctgaagc ttttaccata tccattcttt ttgcatattt cataatactt tctcctcctt
    35281 aataataatt tcttattgtg acgctaagca tgctaatgct attgaattta ttttaatttc
    35341 agctgtatca gaacgtgaac ctaaaattat tggatttgtt gctcctaaaa ctataccagc
    35401 ccacttagct tgattaaatc taagccatga ttttcctaat atattccctg cttctatatt
    35461 tggaaatact agcaaatcaa catcaccagc tatattactt ttaatacctt tatgttctgc
    35521 tgcatgtgca tcaaatgcca catcaaatgc tatcggacct tctgctatac actttggtat
    35581 ttctcctgat ttttccattt ctacaagtag gtttgcatct actgtagatt gtattttatg
    35641 atctaccatt tcatttgcag taagtatagc agttttagga ttttccattc ctatactctt
    35701 catagtaaga agtgcattta tcattatatc ttttttttga tttaaatttg gtgatacatt
    35761 tataccacta tcagtgcaat aaagaagttt gtgatattga ggtaattcat atactgcaag
    35821 taaactcaat aatctccctg ttctaagacc cgtttcttta tttaatatag ctctcatata
    35881 gacacttgta tttactaatc ccttcataag aactttagct tccttatttt taactatctc
    35941 tacagctttt ttaactgatt catcgggatt ttgacaacct attatttcat gaccttttaa
    36001 tccaatttct cttgatatac tttctatttt atccttgtct cctacaagaa ttggctttat
    36061 aatgtttaaa tctgttgctg atttcacagc ctttaatact tctttgtctt ctgcaacagc
    36121 aacacttaca ataacaggtt caagcttttt agcctcttct aataaattat taaaatcttt
    36181 taacatactc tttctcctaa atattaataa gtttttgcta tttcttctcc attaagtact
    36241 ctaagtgctc ctagagcaag tgcctccatt tccatctctc ctggtactat ctctattgga
    36301 gctagatatg aaactttttc tgctactcct ttgactacca tttctgagtg agatatccct
    36361 cctgtcaaga taactctatc tacattccct gaaagtgaag ctccatacat agaaatttct
    36421 tttgctactt gataaataaa tgcatccatt ataagttttg ccttttcatc accctccttg
    36481 attctgtttt caatttctat catgtccttt gttcctaaat aatcgtacat tcccccaatc
    36541 gaacttactt ttgcgaccat ttcatcatga gtatattttc cggagtaaca caattctata
    36601 agaggatatg caagtaatcc accactcctt tctggagaaa atggaccatc agacctacca
    36661 ccacttccat caatcatttt gccttgttta tgtgctacaa tcgatattcc tgaacctaaa
    36721 tgagctacaa taaagttata atcctcgtat tttcccccta gtttttgtgc aatttttctt
    36781 gaaacagctt tatggtttaa tgcatgtaac caacttgctt tttctatgtc tgatattcct
    36841 gtaatcctcg atacatcatc aaattcatct acagaaactg ggtctactac aaatgattgt
    36901 actcctattt catcagctat agttttagct aataatgcac ctaaatttga tgcatgttcc
    36961 ccatttattt catttctcat atcctcaatc atttcttcac tcacagtata ggtaccacct
    37021 tttatagcct tcataagtcc accacgacca actactgcgt caaaagaatt tatactatga
    37081 ttctcactac ttaaaatatc tactatcagt tgttttctat aatcatattc atcaaatact
    37141 ttagaaaaat tttttaaatc ttctcttgta tgggttatat tttttttcaa aatttcattt
    37201 tcatcttgga aaacagaaat ttttgtggat gtaccaccag gatttattac taaaactttc
    37261 aatttaacac cccctagttc tactatgcag aacgtcgttc ttgtattccg gcctaaagac
    37321 ttcgtcctat tgtccagaac gacgttctat attttattaa ttaaatacta acatataaaa
    37381 ataagtattt caataattat tttaaatatt taaaatattc attcgtagtc gtatcctgct
    37441 tcaaatgctt ctacattttt agaattgaat ttacctttgc cttgattttc aaagtattca
    37501 cacataccac tttcaaattc ttcttttgta aataaatcca aactctttac catagcacct
    37561 aacatgcaaa tgttagcagc tttttcattg cctaaatttt gtgctatttc agtaacaggt
    37621 acttttataa cattaatgtc ttctctgtac tttctatcct tacttactag tgattcattg
    37681 acaaacatat aaccattttt tttcattaaa ctttcatact tatctactga tacgctgttc
    37741 attcccaata gtatatctgg attttttaca caaggatttg caattttttc atcacttaca
    37801 acaacattgc aatttgcact tcctcccctc atctcatttc cataagatgg gaaccatgta
    37861 attttctttt ctgccttata tgcaacatac attataattt ttcctgctgt aagaactccc
    37921 tgtcctccaa aaccagcaca tataatttca ttcaacatat tatttcctcc ctaatcaata
    37981 aattctccaa gtggatactt tggaacaagt tcattttcaa ttctcttcat agcatctact
    38041 ggctttaatc cccagtttgt tggacatggt acaagcactt ctattaagca aaaacctttc
    38101 ttttcttttt gtttttctag agcttttttg atgtatcttt ttgttgtatt tatttcttta
    38161 gggttagtta ttgttcctct tgctagatat gctatatcta aatttcccat aacttttaca
    38221 acatcaaatg ttgaaccatg atctgcgtaa tttctacccg ctggagtaga agctgtatat
    38281 tgaccttcta tagtagttgg agccatttgc cctcatgtca ttgcaaacat attattgttc
    38341 ataacaagga atataacatt atcatttcta gtagcagctg acatagtttc cccaagccct
    38401 atcgcataag ctccaccatc tccagctatt gtaaatatat atttatctgg tctaactctt
    38461 ttcatagctg ccattgctgc acccatttta ccatgaggtg gaacgacaac atctacattc
    38521 atactaaatt gaaacatatg attacaacct atatctgaac atataattgt atcttgacat
    38581 atatccattt ctgttaatac ttctccaata attctatcga ctatagagtg tccacagcct
    38641 ccacaaaaca tattttcaca catcattatt gctggtgctt tcttagccat aattaaaata
    38701 cctcctcttg cttagctttt ccatctataa tctgttgagc aaaatctatt aattgattta
    38761 cttctgccat atattgagct gttgctactg aatatactgg aaatctatta tcacatgcta
    38821 taattacatc ttccttcatc tgtgccatca tgttcatttc aactgttaca agtcccttca
    38881 atgaatcact taatttctta aatgcttttc ttgggtaagg ccacaatgtt tttggtctta
    38941 ttagacctaa tttcattcct tttgctctag catctctaac tgcaccttct gctattcttg
    39001 atgaaatacc gtatgccaca aataccactt cagcatcttc tatttctatc tcttcccatc
    39061 tttgttcatc ttcttgaact tttctcattt tttctatata ccctttttgc catgtatctt
    39121 ggtcttcaaa atatgttata tcagttatta ctttattttt ttctcctaca ggtgttcctt
    39181 ttgcagccca tggagcttta tccatatcgt attctttcat tggtggtgct atacaaggtt
    39241 ctaccatttg acctattgta gcatcagaaa gtataagtac tggatgcata tatttttcag
    39301 ccaattcaaa agattcatat gccatatcca tattttcttg aacactgtta ggcgctaaca
    39361 cgattaaatg ataatctcca tttccaccgc cttttactgc ttgccaataa ttatcttgac
    39421 cagctcctat aaatccatca cctataccat atctttgcac acatgctaca actgctggca
    39481 aaccagctga tacccaatat gcaatacctt cttgttttaa tgaaaatcct ggaccagatg
    39541 aagaagtcat agctcttgct ccaagtgcac ttgctcccat aaccatattt acactggcta
    39601 tttctgattc accttggata aatactcctc caacttcttt ttgtctccat gccatcattt
    39661 ctaatatttc tgattgtggt gttattggat aacctgcata aaatctgcag ccaccacgta
    39721 tagcaccttc tgctaaagct tcatttcctt taattaataa actttgcata ccttttctcc
    39781 cctctaataa aaataattta taatatctca aatactaaat cagggcacat tgtataacaa
    39841 gcgccacatt gaatacattt ttcttcatcg actttaatag ttacaaagcc ttttttattt
    39901 gtgtagtcag aaagacttat tgcatctttt ttgcaagctt caatacaaag atagcatccc
    39961 ttacatcttt caacactcaa cttgactttt tccatttctc aaatctcccc tttatgtaat
    40021 atttttactt aattttaaat atataatatt tatattttgt ataaatacta tatatgcatc
    40081 aattttgttc tatagtatag aaccttgttc tatttttatt gcttaattaa aagataacac
    40141 attcgcttat atatttcaat aacattttaa attttaagaa tatttaattt tagattaaag
    40201 aaaaataggc tacatttaaa ctgatattta caaataacaa tttaaatata gcctattttt
    40261 attatcgaga ttaaaaatca tctaaaaagt tcagatatac tttttgcagt ttctataact
    40321 cttttaatct tatactcaaa gtccccttct ctcattctta tagttggacc tgacaaactt
    40381 atggctgcaa tagctttatt atttttatct aagataggtg ctccaataca agttagtcca
    40441 tgttctagtt cttcatcatc tatagcatat ccttgttctt ttatttttgc taaaaaaagc
    40501 atcatatcat cccaattatc aattgtatgt tctgtatact tgtgtattgg tgtttttcta
    40561 tatttttcaa aatctataga atcattaaat gccataagac atttaccaac tgctgaacaa
    40621 taacattcac tacttgaacc aacggatgga tttactgaaa gtaattgatt tgaaccatac
    40681 tctttatgta ttatgatact tcttggagaa tcttgagctc tttcttctaa tatagataca
    40741 ttaactactt cgttaaattc ttgatttaat tttttcgtat atggttttac tatttcagtc
    40801 aatgacattt tttctcccac aaccatacct attgcatata aatttattcc tagccaatac
    40861 ttaccattct ctgcattttg tataacaaaa cctttgtttt caagagtaac caaagttcta
    40921 tgtacagtac ttttatatac tcccatagcc ttacttattt cagttattcc catttctctc
    40981 ttttcatgat ataacagcaa aattatgtct agggctctat ctaatgcatt tattatttct
    41041 cccatataca aaaactcctc ctgcaaatat taagtgctac tcccacactc tactaaatat
    41101 tatatattaa aattacaaaa ttatctattt atcttaatta tattttataa aacaaaaata
    41161 ttatacttaa tttgtaaaat aaaaacaaaa tactcactat gtccttatta ttcttacttt
    41221 taatagaatt attctgttat atttttatcc tgactagata ataatatata tatctattat
    41281 acaatagata tatttttata caagactaac aatgaggtga aataatggat aattttaaaa
    41341 agatattgtt aaatgaacta cctaatttta aagaatattc ttcaaaattt ttaaatggag
    41401 aaataaataa aatgcaatat aagggatttt ctggtggata tggtgtttat gctcaaagag
    41461 acaaaaaatc ttttatgata agacttagag tatctgctgg agttttatct cagtatcaac
    41521 ttaataaaat ctatgaaata gctattaaac acaacttaga taagatacac ttaacaacta
    41581 gacaagctat acaattacac gatttatcta taaattcaat tgttgatatc atggaagaag
    41641 gaataaaaaa tgatatattc actagaggtg gtggtggtaa ttatcctaga aatgtcggat
    41701 tatctccatt atctggagtt gaccctagtg aagtctttga tgttactcca tatgcagttg
    41761 ctactgataa atattttatc aaaaatgcta ctacatacca tttacctaga aaattaaaag
    41821 tttcttattc taattgttac acagatactg ctcattgtag tatacaagac ttaggatttg
    41881 ttgctacttt gaaaaatgat gaaccatatt tcagagtttt cttaggtgga ggtctaggta
    41941 aacaacccaa agttgcttta gaacttgatg aacttataaa gccgaaagac gccttatatt
    42001 gtgttgaagg tatgattaaa ttctttatgg attatggaaa ttatgaaaat aaaaacagag
    42061 ctagggttag atatatggtc gaatcacttg gtgaagaact attcttagaa aaatttaaag
    42121 aatactataa attagaaaaa gaaaatggta gtcttgaact caatattgaa gaaatagatt
    42181 actctaaacc tggagttaaa atagatatac aagattctag actaatacct caaaaacagg
    42241 atggtttata cactgtatat atacatccag ttggaggtat tttgttaaca aaggatttaa
    42301 gtactttact taaagaatta gataatgttg aaaatcctat gattagacta ggaatgacag
    42361 agggattata tattttaaat ttaaatggaa atgaagcaaa aagaatatta gaaataagta
    42421 aaactattag ttgtaattct caattagaac aaagtatatc ttgcataggt gttccaattt
    42481 gtcaaatggg catacaaaat agtcagaaaa tgttacatga aatcatagat tattttagat
    42541 tacaaaataa tgaagaaatt ttaaataaag cacctaagtt atatatatca ggatgtttaa
    42601 attcatgtgg tgttcatcaa gttggtagca taggtttatg tggtaaaaag aagaatgttg
    42661 atggtatatc tacagatgca tttgaattat ttgttggagg cagttttgaa ataggtaaga
    42721 ctagattggg aaaatcactt ggagatttta aagctagtga tattcctgaa atgctttata
    42781 aaatatcgga cgcatcatca ggcaattttt atgaatgggt aaattcaaat gataatattt
    42841 taaacaaaat aactgataag tataaaatat aatttattat atttacttac aaaaagcatg
    42901 ggtgtctcaa aatgaacttt ttagtttatg agacactctt tttctatgaa atcaaatata
    42961 ttttcatcat ctcaacaatg aaaaataaga ctatctctat tttgagacag ccttatttct
    43021 tataaatagt ttaaatttta tttataaaca attttagata aatcacaaat ttctagcata
    43081 gtatcatata cttgtttaag taaagcaagt ctattgttct taatagcttc atcattatcc
    43141 ataaccataa ctgtatcaaa taaattatca actactggtc ttaaagatgc aaattcatct
    43201 aaagcaatac catatttctt atcctttaat aattcattaa cttttacctt tacttgttta
    43261 aattcattgt aaagtctaat ttcagcatct tcttttaata aagattcatc aattttatca
    43321 ctttctgctt tttgagctag agtagaaact ctattaaatg cagtaagcat ctccactaat
    43381 tcatcttttt ctagccaatt attaagctct aaagctctca tatgcatatc agaaacatca
    43441 tttatatcag aacttaaaac agcatcaaca acatcatatc ttattcctaa atctttaaat
    43501 agatttttta ctctctcatt gaagaaattc attatttgct caacaacttc ttctttatta
    43561 aaatctaatt cagaataatt atctaaagca tgttcaataa gtacttttat atccacagca
    43621 acttttctgt ccataagtat actaagtata cctaaagctt gtcttcttaa agcatatggg
    43681 tcttgagaac ctgttggttg tattcctata gcaaagaaac ctgctattga atccaactta
    43741 tcagctattg ataaggcaac ccctgcatta gtcttaggaa gtatatctcc tgcaaatctt
    43801 ggaagataat gttcaaaaat agcttcactt acaacatcat tctctcctcc aacttttgcg
    43861 tattcttttc ccataaaacc ttgtaattca tcaaattctc ctaccattcc agtaactaaa
    43921 tctgccttag ataatttagc agcccttata gtatctgcct tttcatctac taaacctaaa
    43981 ctatcaagta tatcagcact taatttttca agtcttaaag ttttgtcgta aatagttcct
    44041 agttttactt ggaatacaac agtttttaat ttttctatgt agctttctaa gtttctctta
    44101 gtatcttctc tatagaaaaa taaagcatct gcaagtcttg cttctaaaac tttttcattt
    44161 ccagctttaa cattgtctat tctgtaagaa tcaccatttc taacagctat aaagttaggt
    44221 aacagttttc cttctttaag tactggaaaa tatctttgat gttgtttcat aggagttata
    44281 acaacttctt ttggtagttt tatataatcc acatcaaatt ctccataaaa agcagttgga
    44341 tattcaacta aataagttac ctcttcaagt aaatcttcat caaattcaac ttctccacct
    44401 aaagaatttg ctacttctat acattgtttt cttatcattt cttttctctt gttttggtct
    44461 aaaactatat aatttttttc taatttttca aaataatctt ctatagaatc aacttctatt
    44521 gtactttcac ctaaaaatct atgacctttt gttacattag aagatattat tccttctaaa
    44581 tcaaactcta atactttatc atttaacaat gcaactatcc atcttatagg tcttgcaaat
    44641 ttaagatttt ttcctcccca acgcatagct tttgggaata ctacagattt tatagtctct
    44701 ggtaatatgt cttttagtac ttctgaagtt tcttttccat cttgctttat agtcgcaaat
    44761 atatattctt cttttccaac ttgtttaaaa tatatgtcag attcgcttaa tcctttgctt
    44821 tttataaatc ctaatgctgg ttttgttaaa ttattttctg catcaacagc aattttctta
    44881 gcaggaccct ttatttcctc ttctaaatca ctttgtctat cactcaatcc ttcgactact
    44941 aaagtaagtc ttcttggtgt cccatacgca tttattttat caaaagctat tctattttca
    45001 tcaaataatt tactaagatt gttttttaat tgttctagtg tactgcctac aaatcttgat
    45061 ggcatttctt caacaccgat ttcaaataaa agataatttt tcattatttg tcaccgtcct
    45121 ttaaaagagg gaatcccatt tcttctcttt gttttacaaa agtttctgca acagtctttg
    45181 ccatatttct aactctacct ataaatgaag ctctttgact aactcctatt gcacctcttg
    45241 cgtccaatgt attaaatgca tgagagcatt ttaacacata gtcatatgaa ggtattacaa
    45301 ggccattttc cataagtctt aatgcttctt tttcatatat atcaaacaga ttaaacaaca
    45361 tatctgcatc acataattca aatgcgtaca ttgagttttc atactcagct ttattaaata
    45421 cttcaccata agttatttta tcattccatt ttaaatcata aacactatca acttcttgaa
    45481 tgtacatagc taatctttct aatccatatg taatttctcc tgtctcaagc tcacattcaa
    45541 tattacctac ttgttgaaaa tacgtaaatt gagttatttc cataccatct agccaaactt
    45601 cccatccaag tccccaagca ccaactgtag cagcttccca gttatcttca acaaatctta
    45661 tgtcatgctc acttgggtca attccaatct cttttaaact ttccaaatat aattcttgta
    45721 tattatctgg agaaggtttt agtataactt ggaattgatg atgttgatat agtctgtttg
    45781 ggttttcacc atatcttcca tctgctggtc ttcttgaagg ctctacatag catacttgcc
    45841 aaggctcagg tcctaatgat cttaaaaaag tattaggatt catagttcct gcaccttttt
    45901 caatatcata aggttgcatc atgatacaac cttgctttga ccagtatttt tgcaacgcca
    45961 gtatcatctc ttgaaaattc ataaaaatcc ctcctataac aataaagcct ctcgtctaca
    46021 cgaaaggcta ttttaatagt tcttctacaa cttttagaat atcaaattct ataaaatttg
    46081 tcaatgttag tgataattct tataattatc ttctcttcat tttttaaaag tcactttata
    46141 tctatttatt ttcgtcttcg tcttctttat tcttttcaga ttcttctttc ataaggtcag
    46201 cagttacatc tttgtcatct tcttttttgt caactactac atccttcaca tcttttgctg
    46261 cattagttat catattcttc aaaacgtgaa gtttttcttc attcaattca cctaaatcta
    46321 caatttctcc atcttcttca ttttgaactt ttatacgata tttacttata acagcagctg
    46381 ataatccaac taaagtagct aatggtacaa aagctaatcc aacaactcca actgttaaag
    46441 gaatgttcat catagttttt ccatcttttt caactattat tctcactaca ctactttttc
    46501 taagaagctc ttttaattga aactttatat tttctccatc tttgccaaat acttcttcca
    46561 tagtttcttt agcagatttt gctttacaat tacaagtatt ttttttattt tctaaatata
    46621 ttactgcctc aattacatct ccattgcaca ttactaatgc ttcttttgct tctgcataag
    46681 ttgctcctgg aactctttca aagactgaat caaccatttc aatagttata ttactactca
    46741 tcattatcca ctcccttatt attttttaca ctttgcaata cgtgtaatga tttaaaatta
    46801 atattatcaa cataaacttt caaatacttg tctagaatat tctcaagttc atgtgttata
    46861 tattttgata ctttagcttt actacatgtt aaaatatcat ttcttaatac atattccata
    46921 agacttatag ttgttaagtc taattttata ttattatcaa aaagtttact acacttacta
    46981 catagtatac caccttcgta gatattaaac acagaatttt gtaaaatttt acattcacaa
    47041 ttaatgcatt tatttactat aggtttaaat cctatatagt ctaaaaattt taactcgaat
    47101 gctgctgtta taaacctatt gtctgtatta tcctgtgtat acaaatacag agtctgcgca
    47161 agtaatataa atagcctatt attagtctga ttttcaagta tagaattttc aactaatttt
    47221 gtaatatatg tagcataaga aaatgcctct atatcatagg atatattata aaaacttttt
    47281 attatttcac tttgagtaac cttgtacata ttaccttgtt tttttaaggt aaaattgcta
    47341 taagaaaata actgtgatga tgaaagcaaa gagctcttat tttttttagc tccttttgct
    47401 attgcagata cttttccaag ctttcttgta aatagtgtaa gtattatgtc actttcctta
    47461 taccttatag ctttaagtac tatcccctgg gtgttcagga ttatcatcgt cttctttttt
    47521 ctcccttact tcttcaattt cttcatgtat gtttttgcaa tcacagaaat ataaatatgc
    47581 atctatacta cctgtttttt taaaaacttc ccaactgata ttgttcattt ttaaaaaacc
    47641 cccttcttac atttatactt atatttttag taagaagagg ataaatcata cataaagtta
    47701 ttaaacaatt tttgacaata atgccgttgt tattataaag taaactgcta taccagttat
    47761 atcaagagct gtagatataa ttggtgatga aactgtagat gggtctgcat ccattttttt
    47821 taataaaaca ggcataaacg cacctattgt tgcacctaaa accatattta taaataatga
    47881 tattgaaaca attaatacaa tgtctaactt tctcataaca aagtaaatta caatacctgt
    47941 tattatacta cacaaaagac ctgtaataat acctacaata ccttctctaa ccacattgct
    48001 aaaatttaaa tccttattag ataatgttat tactgtaaca gatgatgatt gagttccaat
    48061 atttccaccc ataccaatta ctacaggtat aaaaaatact aatggagcat atacaggatt
    48121 cattatatag tctaagttag aaagtattaa cgaagccaac aaccctccaa ccaaggtaat
    48181 aattaaccaa ggtaatcgtc ctctaagtgc tgatattatt tgctctctca atgtagggtt
    48241 ttctttttca gcaacttctc tttcatgttc tgaacttcct gcaaatttat acatatcttc
    48301 agttgcttct tcttccatta catcaattat atcatctact gttattattc cttttaattt
    48361 ttcttgtctg tctactactg gaattgctat taaattgtat ttagatacta atcttactgc
    48421 ttcttctcta tcttcatcta cataaacaga aattatattt tcactcatca aatcttctac
    48481 tatatttgcg tctctagcta ttattaattc tcttaatgac aatactccaa ctagtttttc
    48541 ttcatcatca accacatata tataataaat agtttcagct tcttcagctt cttctctcat
    48601 atggtctata gcctcaagag ctgtcatatc tttatttata gaaatatatc cagtggtcat
    48661 tgttccacca gcagaatctt catcatagaa tagtaactct tttacataat cggcattctc
    48721 ttgattcaaa agatttatta tgtgttctct ttcttcttct tcaagttcac tcaacttgtc
    48781 tgccatatct ccaagagaca taagttcaag tatatttttc gagtgttcta catccagttt
    48841 agataaaata ctaataaaaa actctacact accttcttct aatatagaag atgccatatc
    48901 taaaggaagt acttcaaata attgaatttt catgtcttcc tctaaatttt ccattatatc
    48961 gaatatatca attatatgat attcctctat taattctctt aactccaata ctttattatt
    49021 atcaattaat gattttactt catataataa atcttgggaa gcatccagtt tcctatccat
    49081 ataacccacc tttatttatc attatatcca aaattattta tataattttg taaatttctc
    49141 caattttctt tgactttaac ccataattga agatttattt gtgaacctaa aagcaattct
    49201 atatcttgtc ttgctgactt acctattcct tttagtttcc taccattttt tcctattatt
    49261 atgcccttat gtgaatctct ttcacagtat attacagcag atacatctac tatttcctta
    49321 tcatttctcg ctttcatttt ttcaatttca acagctacac catgaggtat ttcatcatta
    49381 agatagtgaa gaactttttc tcttataagt tctgctatta atactctttc tggctggtct
    49441 gtaatcatat aatctggaaa atactttggc ccttcttcta aataattttg tataactttt
    49501 attaaggtat ccgtattctt tccttttaat gctgatatcg gtactatttc tttaaaaata
    49561 ccttctctat catacatttt gattatatca aatagctcat ctttttggtc tagttggtct
    49621 attttgttta caactaaaat tattggtgtc ttaacacttc ttaaatcctc tattatcttt
    49681 ctatctccag gacctatttt tttagaatca tcaactacaa ataatattaa atctacattt
    49741 ttaaaagctt ctgttgctgc ctttaccata aattcaccta atttattttt tggtttgtga
    49801 atacctggtg tatctaagaa tactatctgc atttcttcat ctgtatatac tgcttgtatt
    49861 gtatttcttg tagtttgagg tttatcactc attatagcta ttttttctcc aactacatta
    49921 ttcattaaag tagattttcc tacatttggt ctacccacta tactgacaaa acctgatttg
    49981 aacattaact gtctcctaac tttttatctt cttgttttaa ttacttaaat ttatttatac
    50041 ttttaaattt attttaaatc atttccagag aaatagtttg gcaacaaatc ctttatacta
    50101 tgctcaaaca cctctccttt agtatatccc gttattattt ttatatcaga accaaactct
    50161 ataattacct gcctgcatat tccacatgga tatgtttgct cattattttc tgagttatca
    50221 cttgctatag ctattttata gatatcctta tcaccctctg atattgcttt aaaaatagct
    50281 gttctttctg cacaatttgt tccacctaat gatgcacatt ctatattaca tccagtataa
    50341 actttaccac tcttagttaa aagagctgca cctactctaa aacctgagta aggagcataa
    50401 gaatgttgtc tggcatcttc tgccaacctt aacaattcta tgttatccac aacaactcct
    50461 cctgtataca ataattaaaa gttattttta tttaatactc tacattatat cataaaaatt
    50521 taattagcac agatttgttt tattttaaat attttatgta catttatttt aattatagaa
    50581 cattccaagc tgaaatacta atatagctat caacacacct aataaagctc cagcaatagt
    50641 ctcccaaaag gtatgtattt ttccttcaat tctactttgg gcaactaata cagccattat
    50701 atatgcaaga gtagaggcaa caactctttc agtcataagt gtaattgcag ttgctatggc
    50761 aaatgctaaa gcagcatgac cacttggcat tcctcctttt agaggagtac ctgtagaagt
    50821 caatgctttt acaactacaa cagctataag aaccaataat atacatatca aggttatatg
    50881 taattctgat tctcttattt tataaattaa tattccagat atatctgtca atttatcata
    50941 aaacaaaata tatccaacta ctactgaatt tagtgctgcc actagaacgc ctccagctgc
    51001 aacatctttt gctatcttag caagaacatg atattcatca gttactaaat caacagcttt
    51061 ttctatagct gtattaaaca tttcagcaac tacaactaaa catatggaca taagtaacat
    51121 tatcatttct aattttgaaa agttaaaaaa caaacttatt ataagaacag caactgaacc
    51181 taaataatgt attttcatat ttctttcaaa tttaaatgta tacaatatcc cttctatagc
    51241 tgcattaaat gctttaatta taccttgacg agttttttct ggtttcataa aaactactcc
    51301 cttgttatgt ttaacttatt taatatgtgt tcttcttttt ctctcatttc ttttgtattt
    51361 tcatctgtat cgtggtcata acctaaaaga tgaaacatac tatgacatat taaaaaacat
    51421 acttctcttt caaaactatg gttatactct atactctgtt ctaaggctct ttcaagagat
    51481 actactatgt cacctaggga ttcttcttct aactcaacat cctcaaaatc atcacttaaa
    51541 agaggaaatg ataaaacatc agtcactcta tcaactcctc tatattctct atttaattca
    51601 tgaatctctt tattatctac aaaagaaaga ctcacttcat aattatcatc atatccttca
    51661 taatctaaac attctatgat tatatccttt accttttcaa ttaactcctc acttacttct
    51721 aatttatctt gtctatcatc tagtatcaaa tccattcact acacctactt tttattcatt
    51781 aataatgcta tatatctata ttactacact tttactttct tttgaaagtc ttttcctgca
    51841 ttttcgcttt tttacgttct tcttttttaa attcttctct tttgtcgtgc ttctcataag
    51901 ctcttattat tctctgtacc aactcatgtc ttacaacatc tctatctgtt agcattatag
    51961 acccaatacc tggaacacct ttaagaatct ctgtagcttg tattagacca ctcttcttat
    52021 tttgtggtaa atctgtttga gttacatctc ctgtaactac agctttagag ccaaatccaa
    52081 gtctagttaa aaacattttc atttgttcag aagtagtatt ttgagcttca tccaatatta
    52141 taaatgaatt atcaagtgtt ctacctctca taaatgcaag tggtgcaacc tcaatagtac
    52201 ctctttctaa atacttatta aatttatcag cacccaacat ttcaaataag gcatcatata
    52261 gtggtcttaa atatgggtca actttgtcct ttaaatctcc tggtaaaaaa cctagactct
    52321 ctcctgcttc cacagctggt cttgtaagta taattctact aacttcatct cttttaaaag
    52381 cttttactgc catagcaacc gcaagataag tctttcctgt tccagcaggt ccaacaccaa
    52441 aagttatatc attattttct ataagtttta tatattcttt ttgacctaaa gttttaggtt
    52501 gaacagcttt tcccctttga gttatgacga ttgtcccctc aagttctttt attttttgtt
    52561 cacttccttc aagcaaaaga gataatgaat aagaaatact ctgcttatct aaatgcttac
    52621 catttgatac agtttggtgt aattcattca taagttttaa tgcagaatct acattttttt
    52681 cttctccaat taaaattata ttgccttctc taagtattac atctatattt aaagtcttct
    52741 ctattaattt tacattttca tcaaagttac caaataactc tctttcaaag ttaccatctg
    52801 ctattgtaaa tttcttttgt attatcaatt gaattagtcc tcctaagatt ttaagtttaa
    52861 ttttattagt tgttattgct attattattt tgactattat tactattttg attactatta
    52921 ttttcatcag aattgttttg gtctttatta tccttattat cctcatcaaa ctcatttctt
    52981 atatcattta atggtctttt ttctggattg gaaggaatct cctcttcacc ttcatctggt
    53041 ttactttctt cctttataaa cctttctgct tctgacttac taagaggata aattttagca
    53101 atattttcac tagtttgaac tgttattaaa tattctaaca tatttttatt aaccttaaag
    53161 ttatgtttta catctattat tctagccgaa gctgggatta tgtattctaa ctcttttaaa
    53221 gctttttcag ataactcttt ttttaactct tctttattcc tttttacttc aacctttttt
    53281 gtttcataaa aagtactcgt ttttatcttt attggaaaag tatagtttcc tattgatagt
    53341 tttttttctt tattttcaac aacataatct ttatatttta tattttttct cattgtaaac
    53401 tctttatcat aaaaacttag tgtatatata tttttctttt ctccagtttt tttatttaca
    53461 gtatctacat aacttgcctt ttttgtggac tcataaaaag tacttgccca tacttctggt
    53521 attgacttgg tattagctcc atttaataag acatctccct tttggactat gtctccagat
    53581 ttaataactg atttaccact tctagggatt accttttcta ttataccatt ttttaaagca
    53641 attacattac aataatttga ttggtctgta gattttaggg attctgcctt ttttgtaaca
    53701 gtaacaaata tatttgttcc ttttacattg atagataaat atgccacatc attaaatttt
    53761 gacatcatat ggtctctaac ttcttttcta tcaatactct tcttatagac tcctggtctt
    53821 actccaacct tataaagctc atttctaaga gcttcttttt ttataccttc aggagattgt
    53881 atatatacat ctgtcacaaa ctgtgatgta gacatcaata aaaataaaga aacaagagca
    53941 caaatccaca tacctttgtg cttataaact cttttgataa taaaagggac cccagttttt
    54001 tgctttacct ttatatcaaa cttacttcct ctataaacat tcttaaattc ttttatatct
    54061 tgtctatcta tatgaaactc cattttagta ttttttattc tagttacatt gtaaacactt
    54121 atcccatttc ttataagatg atttaaaaat tgttcgagtc ctactccttc cacaactata
    54181 acatagtatc cccttataaa acttatcaag tgtatctcct cctaatcaac atactcaaca
    54241 ttgtagataa tcccttttat acctatctca ctatcagtaa tatacttaag tgaaagttta
    54301 tccccagata ttttaattgt tttaacttta gtctttattc ttattaaatc aacttcatat
    54361 tctaatattg atagataatt ttctatacta ataaacgtat tacttgtaac agtaataact
    54421 ggttgattta cttgtaaatc agtggatatt tctaacataa gcattacccc cttaattaat
    54481 tttatgcttg aaataggtat ttatgcactt tattgatgtt gtaatagatt agttttaaaa
    54541 tttttatata ataaatacct aatatctaat atattattta aacaataaaa aggtaatcat
    54601 attgataaaa aatcaacatg attacctttt tattttttct tatataaaat ctaaacgtat
    54661 acaattttta ttagtcttgt tctattaaac catatccacc agctttacgc ttatacacta
    54721 tgtttatttc aaaattatct tggtttctaa acatatagaa attgtgtcct actagttcca
    54781 tttgaagtat cgcctcctca gaactcatag gttttacatt aaatttcttt cttctttcta
    54841 ttactatatt ttcatcttct tcatcatcat aatcataatc atcaaattca ctgctattat
    54901 ctataaagtc aagattttca aatcttatgc tcttattatt ttgaactttg tctttaactt
    54961 tagttttata tttgacaact tgtctactta atttgtcaca aacaatatca attgctgcat
    55021 ataagtcatc ttctacgtct tctgctctta ttatttgacc gttaatagga attattgtaa
    55081 cctccacttt ttgtctatcc tttttcgcac ttactgttac tttcacttct gattcaggat
    55141 caaggtattt ttctaaccta cttaattttc catctacgta tccttttatt ccgtcagtta
    55201 atttcatttg tctcccagat actattattt gcataaaaac ctctcccttc aagcctttcc
    55261 aattctaata ctttaatatg ttaatcttta aatacaattt ttataaattt attgtattta
    55321 aattaatatt attgtatatg aaaatgatta tttttaatag tctatttatt tttcgtttgt
    55381 tatgatatta ttaaaagtac agggtaattt acaaaatctt tacattctat ttattaataa
    55441 accatataaa atagttcaaa aatcctgcat aaacaagcca cattaaataa atcaaattta
    55501 tgtatccaga tctcttatct attttagaaa acttcgaaat cattattata gaaaccaaaa
    55561 tcattattat tatatctatc aaagctgtaa atctaagtcc aaatccaaaa aatagtatac
    55621 tccaaataaa gtttaataca agttgtaatc cataataaaa aattgcatct cttactttag
    55681 gtaagttgta accctttctt aatattaggt atgaagatat acccatcaat atgtacaata
    55741 tagtccaaac tataggaaag ataaaagctg gtggtgcaaa gcttggcttt gtgagttgta
    55801 aataataggt tgaaatatct gttccactga taatcattgt taagatgcta cttaagtaac
    55861 ctattattag tggtataaat atgtttatca aaaaattcct aatctctttt actgatataa
    55921 tcaaattttt ccccttcttt caaaattttc tttgattata gatatgctca aatatgactc
    55981 gttattccca aaaactataa aaagcctaga gatttctctc taggctatat caatctattg
    56041 taagttttgt tttaccaact tatttataag ttttccgtca gctcttcctt taacttttgg
    56101 ttggataact gacattattt ttcccatatc cttcatagaa gttgccccta cttcagatat
    56161 agtagatttt acaatttctt ctaactcttc ttcgcttaat tgttgaggta ggtactcttt
    56221 taaaacttca atttcacctt ctgtttcttt tattaagtct tctcttccag ctttttcaaa
    56281 ttcaactaat gcatctctac gttgctttaa ttgttttgct attacatcga taattccatc
    56341 ttcatcaagc tcgaccctat tatcaacctc atactgcttt atagaagctc ttattaaagt
    56401 tactacagat tttctcactg tatctttgtt tttcatcgaa gatttcaaat cctcttgtaa
    56461 cttttgctta agggacatcc ccttcacctc tttattctta tttactacta tttcttagcg
    56521 ttttttcttc ttgctgcttc agcttttttc ttacgcttaa cgcttggctt atcatagtgc
    56581 tctctttttc tcacttctga catgatgcca gacattgcac attgacgctt gaatcttctt
    56641 aaagcgctgt ctaatgtttc attctctcta actcttactt ctgacatttc tttttccctc
    56701 cctccaatag cgcaattatg ctgggactgt aactatgttc tttttgcata atatgcatta
    56761 caacctaaca ctttgtttat tataaactaa atttttactt ttatcaagta tttttatcaa
    56821 gaaggaactc aatttttcaa taatttagtt tagttttgtc ccgcttcgta attaggaagc
    56881 tttttaccag ctaaaatatg atagtgcaaa tgtttaactt cttgccctcc atcacttcca
    56941 caattattta tgactctgaa tccagtttgg tcaaaacatt tctctttagc tattttatta
    57001 ataacaacat gaatatgtga cacaatgtcc atctctttat caggaatatc aattaaacta
    57061 tcataatgtt ttttaggtac aactaatata tgatatggag caactgggtt caagtcatta
    57121 aaagctaaga ctctatcatc ttcataaact ttagttgaag gtatttctcc gctcgctatt
    57181 ttacaaaaaa tacaatccat tctttccacc tcctatctta taaatattat aatttctaca
    57241 tgttatagca aaattccttc tacatattca tcttttacat catttatttt cacttttaat
    57301 atctgacctt gtatattttt gtcactttca acaacaactc ttatataatt tgaagttaat
    57361 ccctcatatt tattgccttc tatattttgt tcaaataaaa catccaactc acggccgata
    57421 aatttagttg caaatttatt aaaatttact ttacttaaat ttaaaagttg ttcacttcta
    57481 aagtgtttca tttgagggtc aacttgattt tccatagttg cagctggagt tccttttctt
    57541 ggtgaatatt taaaaatatg catttgtgaa agctctattt cttttaaaaa ctcgtacgtt
    57601 tttttaaact cttcatttgt ctctccagga aaacctacta ttacatctgt agttattgcc
    57661 acatctggca ttttacttct caatctatct acaatagttt tgtactctaa agttgtgtat
    57721 cgtctattca ttctttttag agtttcatca catccacttt gaagtgataa atggtaatga
    57781 ggacaaactt tatccatctt taaaacttca tttacaaatt catctgtaaa taaaattggt
    57841 tcaacagaac taagcctaat tctttctatt ttttctatct ggtttatttg ttttattaca
    57901 tcaagaagtt taatatccct atcctttaaa tcttttccat aagaggcaac atgtattcct
    57961 gttaatacaa cctctttata gccattatta gccaattttt tcacttcatc gactatacta
    58021 tcaatatctc tacttctaac gcgtcctcgg gcataaggaa tgatacaata agtacaaaat
    58081 ctgtcacatc catcttgtat tttcataaat gctctagtct ttccattagt ttggctgatt
    58141 tctatttctt caaaagcttt aactttcatt atgtcatcaa ctgtactaac tttcttactt
    58201 gaatttatct ttttaatttc ttcaacaatc tttcttctat catttgtacc catgactaaa
    58261 tttacttctt ctatatccaa aatttcttct ggagatacct gagaataaca tcctacaacg
    58321 gctattattg catctggatt cttcttttta actcgtctta tatattgacg agattttcta
    58381 tcactcatat gagtaactgt acatgtattt ataacataaa catcagcata ctcttcacta
    58441 ttgacttgtt cataaccatc tttctcaaat agttctagca tagcttctgt ttcatattga
    58501 ttaactttac acccaagtgt ataaaaagct acttttttca atttattttt ctcctcctaa
    58561 atcacttagt tcatacaaag ctattgttga tgctacaaca gaagctgtct cagttcttaa
    58621 tattctaggc cccaatgata caacattaca attatttttt tgtatttgct ctatttcttc
    58681 ttcagaaaat ccaccttctg gacctataaa aattccaaca ctatctatat tagaatcaca
    58741 tttttttagt gcatgtttta ttgaaactgt tctttcattt tcataagggc aaatatttac
    58801 attatttttt ttcatatctt ctaaagcttc tttaaaactt aaaacacctc ttaattttgg
    58861 tatcttacct cttttgcttt gctttgctgc ttcataaatt attctttccc aacgttcaaa
    58921 ttttttatct tcttttttgt catcaacttt aacaacactt ctcttagttt gaactaatat
    58981 tatttcttct acacccactt cagttaattt ttgaagtatc atttccattt ttggagcttt
    59041 tggaagtccc tggtataacc ttactttaag ttctgattct ctatttatat caactttttc
    59101 taaaatctct aaattaacta tactcttatc tatattcata atctcacaaa tatactcatt
    59161 attattcttg tcacatattt caagtttctc acctagtttg catcttaaaa cttttgaaat
    59221 atgttttaca tcttcacctt ctatagtgca agttttatct tgtagattta tattattttt
    59281 ttcaacaaaa aatctatcca ttatacgtca ccatatccct tattttttaa gcttagaaac
    59341 tattgctgac cattcaccta atttttgaac ttcaactatt tcaaatccat tttcaattaa
    59401 gctttcttta acttcttcta ctttatccaa aattatacct gaagatatga atatagcatc
    59461 ttctttcata aagttttgaa catcttttgc aagtatcttt attatatcag ctattatatt
    59521 tgcaactatt acatccgctt tatcttttat tacatcagtt aaattaccat gcattacaga
    59581 tacacttttt tcaactttat tttcaagaac attttctttt gcaactttta cagccacttc
    59641 atctaaatct acagctacaa cttcttttgc tcctaattta gctgctgcta ttgcaaggat
    59701 tccactacca catccaatat caaatacttt agaatcttta ttcacatact tttctaattc
    59761 tctaatgcac atactagtag tttcatgtgt ccctgtacca aatgccattc cagggtcaag
    59821 ctctatgatt aaatccccat cttgcatagc ataatcttcc catgtaggct ttactactac
    59881 cctttgtcct acttttgttg gtttgtagta tgctttccat gcatttgccc aatcagcttc
    59941 atttacttgg tccaatgata cacttccttc acctatatct ataccaaaat cttttaatcc
    60001 taaaactttt tgctttatta tttcgacaaa ttccatcaca tttttttctt cagaaacata
    60061 agtttttata agaacatcat cttcttcatt ctttttaaat acttcttctt caacataatc
    60121 ccagtctagt tcatttttct tttggaataa aaagtctttt gggtcttcta ttacagctcc
    60181 tccagctcct tgttcatata gtatattcgt tataggttca actgcttctg ttgttgtttt
    60241 tatagttact tctatccaat tattcataag tttacctctc ttctctatag taatattcct
    60301 gtttttccat aacttttatt atatcataaa tataatattt tgttgtttta tattattggt
    60361 tttaaattca agctaataat atccttatat aatagtcaga atatttaaaa atccgattag
    60421 ttaattttaa acctaataat aaaacttcta ttatatctac tatatcaata tttgaaatcc
    60481 acttagttaa tcttaaacat acaaaatctc caacttataa ttattttcgc gatgtacctg
    60541 aaacccactt agttaatctt aaacctcaaa tttattatct atatacactt gtagacactc
    60601 tatctcacaa cttatttttc cttttaaaaa atagttttta cagtgggctt acagtagtac
    60661 tttttgtatt ttcaatgtct aaaggtatat tatatttaaa catatgctca cttcaaaatt
    60721 aagcctacag tactattata ctcaaactta ctactagatt ttagtaccat gtatccttct
    60781 actttgctta ttaatccata ataatataat ctattaaata taaaccctga tacttgaatc
    60841 gaatcttgtt gtaactccct atcttcctta taaaaatctt cttccagaat aattttgtaa
    60901 ctaacatcaa catctctaaa aattttagct gcttccttct tactatcaac aatatttttg
    60961 taaggttcaa aattaaaaat taaatccaat ccatcaaaaa tttctttatt tataccataa
    61021 atattcttaa tttctttatc acaacttata aaattctctt caaaatagtt tttaactaca
    61081 ctattatcat agtaatcatc caaaatagtt tttctaatcc ccattgtaaa aatagagtta
    61141 gtttttaata tgtcctttaa gatgttttta gttgtgttct taagtttgtt atcataaatt
    61201 ttatcttcac taggtagaat ataaaagttt ccatattcat atttattatt tctattgcat
    61261 ctacccattc tttgtattaa gctatccata gttgctaaat cacttattat tatattgaaa
    61321 tccaaatcca aggatatttc tactgattga gttgatatcc aaatattacc ctctccattt
    61381 aatattttac tatatttctc ttttttatct ttgaacttaa atctactatg taaaacatct
    61441 atatctacac caccatactt atcagataaa ttttctttta aaaactcata tgttctattg
    61501 actgaatcaa tagtattctt tattataaga attttttgtt tattttctaa agcaccttca
    61561 actattgact tgatttcttt ttcctttata aaagaaacct ttacatcttt accttcacaa
    61621 atctcttctt ccttgttgct ctcaataaaa actatttctc ctttatcagt aacattttca
    61681 ttactttctt cttgaaaaat aattcccttg tttatcattt gctctttata tgattttgga
    61741 agtgtagctg tcattaagtg aaaatcaaca tctaagtact tgcatgcaaa ctgcataaaa
    61801 tatatcaaaa tcaaaaacat ctttggttcc aataaatgta cttcatcaac agttatagat
    61861 gcatttttta cggctgcgaa tattttttca tatcccggaa atttaaacat actaagtaat
    61921 aactggtcaa ctgttgcaat tacacaaggt ttacaaaaat ttatactcaa atctatatcc
    61981 cttaatgtca atacaaaatc atgttctcca ttatcttcat tctctgaata taagtttata
    62041 tctccatgaa gtaatccaat gtaatcatta ctacttcttg tatctaaatc atttttattt
    62101 tgaaaaatat tttttctata aaaactttct gctgatattt tatttggcac taaaaagaat
    62161 tttcttttaa aagtctttct ataatctgca gctgtttttc ctgaacctgt aaatgcaaca
    62221 gtcagaacat ttcttccaga aagttctctc aacctttttt gtatagtatt gaactctata
    62281 ttattttttt ctaaattacc ctgactctta tatatctcat ttaaaatcat atcatcaatt
    62341 tcttcatcag taaaatcgtt ataaaatttt atacctttct gtctacttga tgcactatgg
    62401 tctattaagt tcagcatccc tttatataaa atatacttaa actttctata atttaaaact
    62461 gaatcttcta tttgaccatt gttataatca ctgtctataa tcatactttc acttaattta
    62521 tctatataat cataatccaa tacatcttca ctaaatttaa aatctacatc taaaatttta
    62581 tttatatagc cttctatatc ttccaaatta aaatcttctt tttctaaaat acctttttca
    62641 atataatcat aaatttcttt ttgaacttta ctagtactta acctcatata atcttcatag
    62701 tttccatgat gtaacattat acttttatat atatataact tatcttcttc tgacaagttc
    62761 attttttcta atatatcttt taaaaatgct ccagaaaata tattatgtct tgctatcttt
    62821 tttaaagatt ttttgtcaga ctctaacttt ttcctctctt cttctgagca actatacgat
    62881 attttattat taatctccat tttttgttgc ataattgaat taatttttcc taaatcgtgc
    62941 aaagcacaac atatttttag tatctctaca tctttatctg aatatagatt tagttctaat
    63001 atagattcta atacttcaaa taaatcctta atatgttcaa ctaatgtttg ttcttgttga
    63061 ttagttctta aattatatga cttagctaat atttcttttt gcatgatatt tttcatgata
    63121 aacacctatc tttcaaaata atttaaagcc atgtaaaaac ttcttttgta tcaatacata
    63181 cattacatac atttacctta atatttttag gatatatacc atcattatca acatatatat
    63241 aatggcaaaa ctcataaact ctatcatctc tatttgcttc taaatcttta tatttataag
    63301 gtaatgcaat caatacacct tgatttatta tagtctcgac attctcttta tctcttaagt
    63361 caactcttac atatgtattc tttaatttta tattttcttt tatagcatca cgagtattca
    63421 taggcataac ctcttttaac tcaacttctt tcacaaaaca ccctttttca cttggtatta
    63481 caaaatcttc ttttcttcct aaatttgcat atttacatgg actttcaagc ttttttttaa
    63541 taaattcaag ttcttcatca tccttgcaag aaataaatat agtcagttct acttctttaa
    63601 gaacttcata gtttaatatg ctattttgag ctttatgttc tttatagtaa tcatagtagt
    63661 ttccttgaag caaaaacttt tctttatctt tgccttttct catatttgta tattcattcc
    63721 aaaaatcaat gttctctcct cttgaaaatt ctagttctct atgatgatgt gttccaatta
    63781 ttcctatatc tatatcagag tttaatcttc tatcacataa atacgttatc attcccatta
    63841 ttgtggtctt agatggtaaa tttaaagtac ttatatattc attttgaaat acttttgggt
    63901 ctctatagtg agcagttggt tgcttaagtt tacattgtaa tactttcata attcaaaaaa
    63961 cctcctactc ttttaaatac cacatattat cttctccaat ttccaatcta tctgctagat
    64021 ttttaatctc ttttacaggg tatttactta aattaaactt atttaattcc tttttattag
    64081 aaatttttaa tttgtcattg atagcaagta ttgtgttact ttctttaagg ctataacttt
    64141 ctatagtttc tatgactccc tctaaattta tctcaccact atcagcatta taatctacat
    64201 catcccaaaa aaacggtaca actttatcaa aagctccacc cattactgca agtggtttta
    64261 acagtactga tgaatgtttt atgtttcttg taaacacagt aattgcatct aatatatctt
    64321 ttactgcttt ttctcttaac tccttactca taaattttct ttcttctggt aaaagcaact
    64381 ttccatcttc tacttctact actcctattc tatcaagctc caatgttatt gtataaacgt
    64441 agtaatctga taaagtctct tctattgcca aggcttgtga tgttggaaag ttttcatctc
    64501 taagtacttc attttcttcc ttctcatcat aatattttct accaaattcg ctacttaaaa
    64561 aacctctatt tgttatcaac tgtgttgaac ctctatatga atttaatgac ctaaaaggta
    64621 ttattctaag cggagaagcc ttacttatag aacctttatc tttaagtggt atcaaataac
    64681 caaatacatc agtctctaat ccattttcat ctacacatcc tacattttgc ttaatagatg
    64741 gatatatatt tccttttttc ccaaaaataa tattacttaa attccaacca tattcttggt
    64801 ggagcattct tcttaaatca tatgttattg tagctatact agtttttgca tgtatttttt
    64861 ctctatattg ttcttttttt attggtgtat aatttccata cccttggtca tatgaaagtg
    64921 gaactgggct ttctgtcagt atagttaatg ttactccttt tactcttttt tcattcattt
    64981 taaattttcc ccctttttta tttcatgatt tcttgaataa atagacctac attcgtattt
    65041 aattctaatt cagaactctg cattagacct tctacaaacc cttctcctat taagattcca
    65101 ttagaaacta acacatgcat tatagtttga aatagctgag ttctatcatt agacttaagt
    65161 agttgaatca ctttcataga aaaatttttt cttctggatt catctgtcat tttattaaat
    65221 aagtctttac ctactcttga atatattaaa ttactttcca tatagttttt cattttatac
    65281 tcctcccctc catctacaat ccaacacaat tttatatata aaccgatatt atatgagcta
    65341 gatacaaaat ccatttctcg agaagttcca gttgatttct ttaaaacact tatattatca
    65401 agtaataatt cttttaaatt tgataaattc ccattatcaa tcattttttt acccaaattt
    65461 ctagtattcc ctggctctct tgaaaaatta taattatcta taatatctat aagttcaatt
    65521 ttttttaata attctttata ctctataata gagtcaaact ttagaattat acctttattc
    65581 gtatcaatat caaacctata tagtctaatt gaacttattt tttcatgcaa aagtttttta
    65641 taaaatgatt tatctgaata catttttctt ttaagcatta tcttatgatt taaaaatgct
    65701 aattctctta aatcattcgt atatgcaaaa accattggtc tttttaaatt tatatataaa
    65761 agacacatta agttgaaaaa ttcacactca aaacaaatat tactttcaac ttgtccactt
    65821 attttaaagc ctgatttttc tgcacctcta aataaaaagt tatacttaga atcctttcgt
    65881 tctcttaaat caatatctag ttttgttgtt ttatttatat tacaaacatt acatacacta
    65941 tctttttctt catattgtgt caaatcaagt ttatctatct ctatatttga tttaattaca
    66001 gtatctacta tcctttttac atttgtttcc atattttcta gactcgtgtt taatccatac
    66061 ttaccactat ttctaacata tggaaatctt ctgtttttaa aatctttttt aattccttcc
    66121 ttttgtttct cagttgcaga agatttatct aattcttcaa taaaatttac atacgttaaa
    66181 ttatctatat tactaaatat tttttctaag gtttcctttt tcccattttt aaatacctta
    66241 aaaagttgat tttctaatat ataatcagat atatacttat ggtctatata ttctgcagat
    66301 tctaaagata aataatttct atttaactca caagtaaatt ttagcttata atcatttttt
    66361 tctagttcgt tttttaaatc cattagtaat tcataaaagt aaacaatgcc aatatctctt
    66421 acaatatcac ctgatctata aaatttagct tttatttctc tcacctcgct actttaatat
    66481 atcaaccatt cctgcatttt ccgtccttct atatccaatt cccattttat acagtgcatt
    66541 taaatcttcc atatctcctt ttaaaaaaaa tgttcctgca taagcattta tatagtaata
    66601 ttctctcact ttaaatccac gaatcttttc ttttaacact ctttttttga agttaagagg
    66661 tataaattcc aatggctttc taagcccact acctcttata ctctccagag ttagattagc
    66721 tatatagttt aaacattcta tataatttga atcttctaca tctaaatatt taccttcttt
    66781 attctttact attataggag acatagtttt aaatataaca ccattttctt ttatctcgtg
    66841 ttctttatgt atttttatat tttttatttt aaatctataa cctttatatt ctagctcctt
    66901 tacttttaaa attccattgt ataatttact gaacatagaa taattataaa aacttatatt
    66961 gaatattata tctccatcaa caagcaactc atttttgctt cttataagat ttggtatgta
    67021 gatggctgta tttatatcct ttatttgctt attgtttttt ctttcttccc catagttaaa
    67081 tatattttta gcaaaatctt tgttttctgc atttaaaata ttttttataa aggaaactga
    67141 caacattgaa ttttcatttg gaaatttgcc attacatgac tccataaaaa ttgaaattct
    67201 gctcatattt tcacctccta ctttctagta taattcatta ttctctattt gtaatataaa
    67261 aaataaaaca tatcataaaa tgattttttg ataataaatt taattttgtt ttttaatttt
    67321 ttaaatatat tttactgtta gttttattct ttgctaaaaa tcaaatatac atattaaaca
    67381 aatacattta gtcattttac acatttaata taataaaaaa atttgatact atatcattaa
    67441 aatttaaata tcaaggagaa tattatgtca gaagtaattt taaaaaatat atcaaaactt
    67501 tactcaaatg gatttaacgc agtaaaaaat ataaatatag acattaaaga taaagaattt
    67561 atcgttttag taggaccatc tggttgtggt aaatcgacta cacttagaat gattgctggt
    67621 cttgaagaaa tctctgaagg agaactatac attggagata aacttgtcaa tgatatagaa
    67681 ccaaaagata gagatatagc tatggttttt caaaactatg ctttatatcc ccacttatct
    67741 gtttacgaaa atatggcatt tgcacttaaa cttagaaaat tgcctaaaga tgaaatagac
    67801 aaaaaagtta aagaagctgc taaaatatta gacttactac ctcttttaaa taaaaaacct
    67861 aaaacattat ctggaggaca aagacaaagg gttgccttag gacgtgcaat agttagaaat
    67921 cctaaggtat tcttaatgga tgaacctcta tccaacttag atgcaaaact tagaactgct
    67981 atgagaacag agataactaa gctacaccaa cagcttggaa ctacatttat ctatgtgaca
    68041 cacgaccaag ttgaagctat gactatggct gatagaatcg tagtaatgaa agatggagta
    68101 gttcagcaga ttgcaactcc acaagatgta tacgattatc cagctaatat atttgttgca
    68161 ggatttattg gagcaccaca gatgaatttt attgatgtaa tattaataga agaaaatgat
    68221 gaaatttatg cacaaaatga acatattaag cttaaattga ataaagaaaa acactatgat
    68281 ttaataaaag acaattatat taataatgaa gttgttatag gtatcagacc agaagatatt
    68341 catatagaag atacttttat taaatctaat ccagatactt gttttaaatc aagaattgaa
    68401 ataaaagaac ttatgggagc agaaacttat gctcacttaa aactaggcga aaatacgata
    68461 acaattagat ttgacagtaa aaacagaatt aatgttggtg atgacttaac actttcagtt
    68521 gacaatagta gagtacacat atttgacaaa gaaactactt tagctataag ataagaatat
    68581 aatcttattt ttaaggagac tttatggaag agttaaaaga ttttttagaa agacagctta
    68641 ataaaaaaat aaatatctat ccctatgaaa accaaaagtt agatgctagt agccatttag
    68701 ttactttcaa taatgctatt tatgttattg attttctaga taaaaataat cttgataatt
    68761 taaaaggcaa cttttattta atttaccaat ctcatataga ctttgaatac ctaaaaaata
    68821 ttttttataa tttatttgaa gatataaata taatacaaca caatggtttt tttatagtaa
    68881 attctaaata taacttagat attaatgtaa ctacacaaaa tataattgaa actgaaactt
    68941 atcaaagtac ttatattttt tatcttggta aattagatag taaagctgat tttgatttta
    69001 gattacagtt atgttctgat ttactacctc atattataaa agacaacgct gaaaataagt
    69061 ttttaaattt gtttgacctt attagatata aaactttaga tttaattaat gaggataata
    69121 tactcaataa attaatagat tttaataaga ttaaatctat tgacgaagaa cttctatata
    69181 caggaataaa atttataaat aatgatttaa atatttctaa gacatctact agtatgtttt
    69241 tacatagaaa cacgctagta tatagattgg aaaagattaa tgagatactt gggtttgatt
    69301 taaagaattt tgaaaatgca atgatttttt atctaagtgt caaatcttat tttctctata
    69361 aaaaaattta actactaaat taagcagaga tttgaaagac tagttcaaat ttctgcttaa
    69421 ttttaattca aaatattgta tacttatcga gtactctatg cttcaaaact tagaattaat
    69481 aaatatcaaa ccagttatgt tttacaaaca atatttttaa acttatcagt tattagactt
    69541 attaaatcca taaatccact attctacttt tcttaattct ttctttaata taaaatttaa
    69601 taaaaaactt attgtaccta agaccaccat aacataacct aatatctgaa attgttctga
    69661 tgttatattt acttcaaata ccattccaag taaaacagtt gctaaaatag aacctaaata
    69721 acgactagtt tgaaacagac cagaagctgt ccctatactg tcacgaggac tttcttcaaa
    69781 catagaggat tgcagggcta cattaccaac tccataacta atacctgcta atgataatat
    69841 aatacccttt cctattacag gtatatggat aaaaactact gaaagaagta ctgcactaat
    69901 aaacataaag attgatgatg taacaagagg aaatctagtt ccagatttat ctatccattt
    69961 tccagttaat ggagatataa atatacctat accagacata aatagcataa ataatccagt
    70021 cgactttgca ctataatgta aggcatcttg aaaataacta ggaagaccaa aaaacaaaat
    70081 ataattaaag aaatttaata taataaattg caagtaaact tttgacaatt taggattact
    70141 tacaaaaagc ttaatatcta taaatggcaa ttttgttctc aattcatgcc aaataaaaag
    70201 acacatcagt attataccaa atacaagttg ttctaagtta aaagattcct tcatagatag
    70261 caaaaatagt aatataaaaa tcattgcaat tgaaaataga agtatgccaa taatatctaa
    70321 tcttgacaaa acatttttta aagtttcttt tatagatttc ttttctttta cttcttttgg
    70381 gaataaaaaa taccctaagc atatagaaac caaaacaaca ggtatattta caagaaatat
    70441 agcatgccat cctcctaagt ccaacaataa tcctccaagt gtcggaccta atcctgctgt
    70501 agttgaagca aaaatggtta gaactgctaa tgcagaagat tgtctttctt ttatattatt
    70561 ttgtataaga gcaactccag atggatatag ggtacttgtt ccaattgctt gaattactct
    70621 tataaaaatc aatataaaga atgattgaac aagtggtact atggatgctg ataaaattac
    70681 aagcatcaaa ccactcaaaa ataagacctt tctacccatt aaatctccta tcttacctga
    70741 aactggttgt gcaatagcac tagctaggta aaatgctgaa acaatccaag atacagttgt
    70801 aaaactaata tgaaaatcat tttgtatact atgtaaagca agtgaaatca tagaagaatt
    70861 aagaggattc agcatagttc ctgaacctat tgctatcaaa aaaagcgttc ttctagcatt
    70921 tgttttaccc atatatcatc acgcctccaa taagcagttc atttacatta taaaaaagct
    70981 gctcctataa ttcctgcgtc tgaacctaaa gttgcacatg taattgtagc tatatcttct
    71041 gttttgtata atacaaattt tcttaccaaa tcttctattc catcaagtat tatatcgcta
    71101 gatttagaaa tgcctcctcc tatagatata atttctgggt ctaaagaatt tattgtgttt
    71161 gcaaaagttt ttgctaaata ctctttaaat ctatttatta ctttaattgc cactaaatca
    71221 ttttctctat atgcatcaaa caccatcttt gcatttacat tttctaaatt tccctctgcc
    71281 aaatctaaaa tcctactctt ttctccttct tctatcagtt tttgagaata ctttataatt
    71341 gcagttgctg aacaaaaagt ttctacacaa ccattatttc cacaattaca attaaaatag
    71401 ttttctccta taatttgatg acctatttct gaacccaatc catgtgctcc agaaaagact
    71461 ttttgattaa ttactattcc tccacctaca ccagttccta aagtatataa tactccaaca
    71521 ttagcacctt tcatacttcc aaactttgct tctccaagtg ctgctactgt tgcatcattt
    71581 tctccatgaa tttcaacatc tggaaatctt ctttttaact ctttattaaa agctttttta
    71641 ttccatttta aatttacaca agttactaat ccttctttat ttataaaacc tggaacacca
    71701 aatccaatag attttatgtc actcatagta agtttattat cttccaacaa cttataaatc
    71761 attattttta tgtcattaag tattccttca aagccttttt caattactgt tttacactct
    71821 gacctaaaaa ttatcttccc atagttatca actactcctg cttgtatacc tgttcctcct
    71881 atgtctacac ctatataata catctctttt cacctttctc ttttgaatca tttaattt
//
LOCUS       DACTZW010000007        70491 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.007, whole genome shotgun sequence.
ACCESSION   DACTZW010000007 DACTZW010000000
VERSION     DACTZW010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 70491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 70491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..70491
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.007"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(96..356)
                     /locus_tag="JAM15_02585"
     CDS             complement(96..356)
                     /locus_tag="JAM15_02585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797162.1"
                     /translation="MDKLITELSSLGAIGILCALLFKNTMQEKKEDRDMYKKTVENFI
                     ELSTQQQEINKNILVQMGIMKTDVEEIKEDVTDIKGMLQNGV"
     gene            complement(619..972)
                     /locus_tag="JAM15_02590"
     CDS             complement(619..972)
                     /locus_tag="JAM15_02590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797163.1"
                     /translation="MFKFDKNKIEQIKQGRKVEMQYKDISDISIGQAKQDDDITNNFI
                     ANAEIYEMLLSQSSVNEASNISTFSVRKSGGESGMVEVYVALILRGRKTIEEVPAVIR
                     EQVRIRCKELEIPVE"
     gene            complement(989..6313)
                     /locus_tag="JAM15_02595"
     CDS             complement(989..6313)
                     /locus_tag="JAM15_02595"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012632.1,HMM:NF024930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797164.1"
                     /translation="MKRTKLLQRGNFFGDKNMVVDEFDEGYDNYDFINFFTGCCNYTF
                     GLKNNNILYGCGDNSNFQLGLGEDNTTRKLFTKIPNISTNIKKVACGESHAVILTSDG
                     ELLVAGINTDGQMGLGLEKVGKTVSTFEKVLEIKGVKDIACGLQSTYLLYNDGTLYVA
                     GNNLYGQLGLGTNGASANVNTFTKVDVDNVKAVFSYNKSAFIIKNDNKCYSTGFNNQG
                     QLGLGDKNNRDLFSLVSINDVKTIACGSEHTVLMTYNNDIYGCGKEKCFGNALQSSLF
                     TKIEEVNIKTIACGNGNTMLIDNKGILKVAGNNDIYQLGIANYSENIDNSFIDLKNIV
                     AKNIFIGLSHSILIDSNNDSYCTGDNTYGQLGSFFDDMHVVEFKKMDNEKYSYSNYIN
                     LIKSEDKLTLLKEEMEIKDIELPLDIHSVRDVVFSPYCTLVILANGDVYGLGNNGYKG
                     MGSDLPSQLNELTKLSISNVKSIVASKNISGGIFYIKNDDTCYYSGPNSNSIAGVLPS
                     NSDVFKKISIDNVKKVVINTDLSNWFSLIVTNNKQIYTSGKSSTYVNGLSNISASQYT
                     EISLSNVTDAYSSYNATFIVADEKKVYATGINTNYMLGVNVNNETYTTNLRLLSTWSY
                     INPGGTSYSVISCANDITKINNIIIYEYVTIFCTNIGSFLTGYHGTRWIKPTDSNYKV
                     QHQGISYAGCVENYVYNYYPTRCTQSSYSTNFAYLYYGESSSNLKNYNPDNLLISGGS
                     SYIHQYGRNYLNNQSSNNIAASNINSGPITSDKAIFLYKALLYLSSNTLYGFGNISES
                     AKELDVSDTQDGYNATNYKKVMKNIKNIFIPPYDLSRDKTRFAILTDKSLFICGYNSK
                     GTHGISVNSSLNLNNKINYNKKNSSSEISSNIQEIYSHSKSTYLLTNNNMIYSVGLND
                     VGQLGVGDEINRKVFTKINIDNIKSINVNRFTDNSKHAFAIKNDNTCYAVGLNNSGQL
                     GIGDNVNRNVFTKINVENVKYVAVYGNTSLLLTNDGLLYGAGNNGKGQLGLGDTTSRN
                     IFTRIPINGVRDVYLCNDVSIIVKNDNTCYVCGFVNGYFGFTESSISTFTKINIENVK
                     SVVTAGSEATFFITNDNVIYTTGKKERVFFSTETNDIKGIRVINNIINAKKIVVNGYT
                     SAILTNDNKLFVGGLSGYGSIANNNNTNSVEDVKDVFVTANNTLYIDNNNNLISSGRD
                     TYGISDEYYRDMSVPYYKVSIKKDVDTVFSSYNTIFIKDIYGKFYSSTGDNRYNHLGI
                     HHRYDNDKNEALEGSLHSYFKTDDTSDKIVFNKKNEKLVMFNDKYIKTNNKYINYKNI
                     FKDNFKYTSIILPFEVSDIDISKTHSLAVAKDGKLYGIGSNSYKEINQTLEDIELLTF
                     TEVNISDVKKVACGDNYSYIIKTDNTLWSYGKNTEYQLGVGHNNDVRELQKVTGLPSV
                     KDISIYNSMTLVLTNEGELYAQGYNTNGLFGLGESEKDKIITTFTKVLTNVKEIKSHN
                     DDHILVIKNDNSLWITGKNKSMYKISISITDLYEFTKIPVPEHLNDILDIELSDDTIY
                     MITKVDTSKASIEIVEKSISQVRVVVQDPNNVIEKLEMFINDELISTKTNLEINSIIF
                     EIPQNKIVLGENKILIKASSPTGDLYSSMFIFKSETGLKVKKDSILMINNKVYSIINI
                     TENNTDLIVTLNEGLKDDMMENNPIYQLINKTKVQVKINKSDLFKDMKLVEIKKSDSS
                     YQEIYELEEANIKSAQPKIIVEKGDKWTAIKRPSMIFRYDAENNEPQA"
     gene            complement(6330..7313)
                     /locus_tag="JAM15_02600"
     CDS             complement(6330..7313)
                     /locus_tag="JAM15_02600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAT6797165.1"
                     /translation="MEEKFYIILTKIGREKIANATALGELVGLTKFQVGDSNGEYYEP
                     TEEQTALKNVVWEGNINSLRIDEKNPNWIVIETILPGTVGGFMIREAAVLDNENNIIA
                     IGKYPETYKPRAEDGSIKDLVVKMILQLSNTSNVTLEVDPTLVFVTQKDIQDLDDKFD
                     KNIKEIKVKIGEELLSTEAKNLSGAINEVVEKIKNISIDDVIGGQIQTELSVLKNSYN
                     KLSEKVLDILIYLELESEIDVDEAGYWYDTLTNAKNIIAIEGLKLDLNRKCITGELGS
                     VTFKNVVLPFNANRVRYIHEMDNNFVETKSNRAYSIGQTDITLNKYSYEIR"
     gene            complement(7314..8012)
                     /locus_tag="JAM15_02605"
     CDS             complement(7314..8012)
                     /locus_tag="JAM15_02605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2313 domain-containing protein"
                     /protein_id="HAT6797166.1"
                     /translation="MKLIDKLPSFDRNYIVEEIQGAYDTELNILKEDIDDTFDQLFVD
                     TATWGLDMWEDILCIEKKELDFDTRRSNIKAKMRSRGTSTIEVIKSICEAYTKSETDI
                     KVYSDEFTFVLSFIANNCDYKTLLDCSDMIERVKPAHLLHYLEPIILDKSMVYCGGGM
                     VCSEEVKVHPYFEPIIKCSAVVNCGAGMLSREEIKVYPLSIKCIENNCKINIAIANDT
                     GVENVVVYPKSEVV"
     gene            complement(8009..9061)
                     /locus_tag="JAM15_02610"
     CDS             complement(8009..9061)
                     /locus_tag="JAM15_02610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HAT6797167.1"
                     /translation="MYSDQTYEVIKNRTLENINLDIYKGEGSFLNNMVSGNNLELSKI
                     YLELSKIHKMAFIQDTYNQFLDKRVNEFGVYRKLGTESNGEVEFIGEKGTVINNGTII
                     SYRDLLFVVIKDVTIGSEEGDNSPVQALEVGKKYNLPTNCEFKLVDNISGVTKITNTR
                     SFEGGTDIETDEELKERFYKIQRNQATSGNKAHYEEWALEVDGVYNVKVYPRWDGPGT
                     VKVLIFGKNNQAVDTETIERCQQHIDEEKPIGPTITVVTPLPIEISISAVMKLEDGYT
                     LDNVKESFLESINTYFRDIRGEIIYTKVMGILINTTGVHDLSNLLINGSTDNITINED
                     KIPSVTTVNFSEVENQ"
     gene            complement(9054..9482)
                     /locus_tag="JAM15_02615"
     CDS             complement(9054..9482)
                     /locus_tag="JAM15_02615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HAT6797168.1"
                     /translation="MSTIFPFIGVPEDYILPKTEELPIFREVAWDFEKDEPILEKGDF
                     KIIEKKEALKVWIYKCIKTNRYEHEIYSLEYGTELSELIGQKYTKGLTESEASRFIKE
                     ALLINPYILEVNVKSANFNRDVLSANVKVSTIYGEVEINV"
     gene            complement(9482..9808)
                     /locus_tag="JAM15_02620"
     CDS             complement(9482..9808)
                     /locus_tag="JAM15_02620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 domain-containing protein"
                     /protein_id="HAT6797169.1"
                     /translation="MANPINEFIGIIREEGKYHNQPSFFIGKIKSKLPDLKIETNNII
                     LEKEDILIDSWMIDRQLETFDTETNQEHQHEVKNPFIDNFESGDMVIMFRIGEKFAVV
                     SKLVSL"
     gene            complement(9824..11353)
                     /locus_tag="JAM15_02625"
     CDS             complement(9824..11353)
                     /locus_tag="JAM15_02625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase"
                     /protein_id="HAT6797170.1"
                     /translation="MIINRSKDSSSNEISFVSKDMGFLLTQSEVSYNFKDKLVEDIAK
                     QVFAENRLSVGTIAKTNVKYTKMFIGVNGYDTIMSAYTEASKKTKKKYMIEANLDKFN
                     VIEKGTVTLSVMFEEGFNIINTTFSESMENVKNKVIVVDQYGSKISEKIDNEIFKEVN
                     VIMQKVIQQQENQDVDIDSEFNGIEKSCSLKGYGDVSCITGRGVKVKDSYTKLVGLFY
                     IDTDKHTWQNGEYQIELELNFQNLMDEKSAGQDEPKEESNLGGEDYAGGKEFTAEFTA
                     YCPRKEEGGDTDCRKKKLDPSKKTCAAPMVGKYEQTYYTKEFLNKHPLLNYGDEIQVI
                     TGVSGRDGVYKVNDVGPAITIEKNGTYHIDILFGNVEEASKFGRRKGKIIIGGYSGNV
                     SDKAKIVISEAKKHLGKPYKWGGNGPSSFDCSGLMVYCFKKVNVSLPRTSNQQSKKGK
                     KVEQKNLQAGDLVFFHNPVSHVGLYIGNGEFLHAPQKGDVVKISKLSSRRDFNTARRV
                     L"
     gene            complement(11635..12057)
                     /locus_tag="JAM15_02630"
     CDS             complement(11635..12057)
                     /locus_tag="JAM15_02630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797171.1"
                     /translation="MEMWLRQAEDRFRFPVFPSSFSINGKAAVNSSSILKIGEVATFG
                     GVALKSISISSFFPNKDYTFCDYTGFPSPYDCVNKIEKWMKEGFILRFTITETNINME
                     VIIEGFSYEERDGTRDVYFTLDLKEYKRIKIPKVTPKQ"
     gene            complement(12057..14510)
                     /locus_tag="JAM15_02635"
     CDS             complement(12057..14510)
                     /locus_tag="JAM15_02635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797172.1"
                     /translation="MGNVREEGINMYLTDNYTPKMNQIISVTDNFRRATVAVSLSTNV
                     MASSIKNSIGSASSRVNSLNSSLRKVQTTASSVSSTMAKLSSSINAVSGVIGSLNGSI
                     MRLAITIAMIIDYFNKLIQKKNEFNSNIMIILIFKAKSDEVEKTKNKLLGNLKKIGGK
                     IWNIVIKAKDMTKRVISSILGKLKRVEKRPYQGSINLKDMVSSAMARILPKLMLFKNT
                     FWSGVIAIKDMASSIISKVFPKLRLFAGKVWSGAIAVKDMASGILGSIKGKISDLTNG
                     ATIGVAVKKGVDLLGQEQNQKVVLESVMKRNTGKTSQKDVDKYYDSLVNMANDTPFDP
                     EDVVAMGTKAKMISNITGGKKEKDITQAMVDVRALNMNTSSEQDVSAAFLSAAKGNME
                     SLNTLVGENYKTFDEALEGISVKQMGLAKEMSNTIPGIISGAQTSINNGLKSIVKPFD
                     DILGQGLKKIKTFIESGLGNLAGLSEKMAGKIGNVMNGKIIIGNKYDQMQSRSVKNGK
                     EFSDSTQYRISNEAEKRKMMVENKQERFENHAATMIGNAPKAIVNAGSTLLQNIDFTA
                     LIDSLLPVVNLVNNLLDSINNKSPIAQGLISIFGTIVTTAFQLIGPVVEAVSPIITRI
                     FTFLGEYAPQINNFIETLGVIWKTVWETLGPLLETGWKIIEPILGAFFNILDKVCKIV
                     KDICKWWQTMINKIKNGSITGTVLNLVEKSKKNYKDNPYAGTKAGDSGKAYSSKKGNN
                     AFGLNYVPYNDYQTRLHEGEMVLTKQEANQYRSRKNGGNINIAKLADTIVIREEADIE
                     KITSKLVASIQLAQLGGVL"
     gene            complement(14704..15150)
                     /locus_tag="JAM15_02640"
     CDS             complement(14704..15150)
                     /locus_tag="JAM15_02640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAT6797173.1"
                     /translation="MNENGLSKNINIVDLLLNADTENLERPSTIVELKRLSTIFGQEF
                     KVMCRALTISKDEEIQNTCLKIDENMKTDIDLPEMQMLTIIEGVCDLDGKLLFKNKEL
                     MDKFKAPTPKELARKLLLPGEITNLYRILQDVMGYGKNAVIEEVKN"
     gene            complement(15264..15692)
                     /locus_tag="JAM15_02645"
     CDS             complement(15264..15692)
                     /locus_tag="JAM15_02645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HAT6797174.1"
                     /translation="MANMEARNVMSGTWGELWLDGNKVAEVKKFQAKMEFTKEDIIIA
                     GQMGTDTKYMGYKGKGSITLYHVSSRMHKLIGEKIKRGSEPRFVAISKLNDPDSYGAE
                     RIAVKNIAFDDLTLADWEVGVKGEIEAPFTFTEYDFLDII"
     gene            complement(15706..16770)
                     /locus_tag="JAM15_02650"
     CDS             complement(15706..16770)
                     /locus_tag="JAM15_02650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath protein"
                     /protein_id="HAT6797175.1"
                     /translation="MAIGLPSINISFKELATTVKERSARGIIAMVLKDAKALGLNEIH
                     EKEDIPVDLSAENKEYINLALMGNVNTPNKLLVYVIEGEADIQTALDFLETKEFNYLC
                     MPKAVEADKTAIKNWIIKLRDIDKVKVKAVLGKVVGNHEGIINFTTEDVLVGEKKYSV
                     DEFTSRVAGLIAGTPLSQSVTYTKLSDVVDIPKMTKVDAESKVNKGELILIKEAGAIR
                     IARGVNSLTELTAEKGEMFQKIKIVDTLDIIHSDIRKVIIDDYIGKVTNSYDNKCLLI
                     VAIKSYLEELEKSALIESDSTVEIDFEAQKSYLKSKGVDLSYMTLQEIKEANTGSKVF
                     LKAKIKVLDAMEDIDLSIEI"
     gene            complement(16775..17218)
                     /locus_tag="JAM15_02655"
     CDS             complement(16775..17218)
                     /locus_tag="JAM15_02655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797176.1"
                     /translation="MLKYKEILETIIEILKKNFTESIFIDDESVQGSEGSCFFVSILS
                     VICTPIMLNTNNKDIVISIKYLPKPQSKSIRMYEISDELNKLFNRNIKVTDRKLNITK
                     LEQSIKKEESIYVLNFTITLNYLDSVYEEDVVYENMEEINLNLGE"
     gene            complement(17467..17907)
                     /locus_tag="JAM15_02660"
     CDS             complement(17467..17907)
                     /locus_tag="JAM15_02660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797177.1"
                     /translation="MENKKDILFKETDERLHNYKYLDIKIKNINLDIKRCENEYSGCG
                     AMVYTEKTSNTYNISSSVENEVLKREERLRKLKMEKENIEIEKEKIENALTCLNDIEM
                     EFFNLFYNSKTKNNMTYISMKLHLDRTSCYNLKKKMIFKLSEIL"
     gene            complement(18012..18209)
                     /locus_tag="JAM15_02665"
     CDS             complement(18012..18209)
                     /locus_tag="JAM15_02665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6797178.1"
                     /translation="MFKNNLKYYRKCKGMTQIQLARKAGITNDYISQIERGIKNPDLL
                     MAKKISSILEQNIEEVFFIQL"
     gene            18378..18698
                     /locus_tag="JAM15_02670"
     CDS             18378..18698
                     /locus_tag="JAM15_02670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAT6797179.1"
                     /translation="MFAKRLRELRKEFGLTQRELGEKVGVSQRVLGYYETENRFPDEH
                     ILNKLADVFNVSVDYLLGRTLVKENIDTVAAHRKNPHEELPEEAQEQLNDYIEFLLNK
                     YKKK"
     gene            18780..19286
                     /locus_tag="JAM15_02675"
     CDS             18780..19286
                     /locus_tag="JAM15_02675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797180.1"
                     /translation="MNNLDKLFELASQEEIIIHYTTYIAGDLEGLYINKHGIKIISLL
                     SNLKQNSKKLTSILAEELGHHFTSLGYYVSSYNDYYTKIIIDKCENKALKWACEFLIT
                     EEDIINIINSGITCVYEMADILNVDITFFQKRLEFLSLKKQSLQLGNNKYLILTNLPY
                     FYIFDPIS"
     gene            19987..20742
                     /locus_tag="JAM15_02680"
     CDS             19987..20742
                     /locus_tag="JAM15_02680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAT6797181.1"
                     /translation="MEKKVLATVGEKEITNIDIENALKSLDPYQAMQFKTEEGKKHLL
                     NDLVNQELFFLDAKEEKLDEEEIFKLEMKKIEENVLKQFAINKVLSSVNVTEDEKVKF
                     FEANKSSFSKPESATAKHILVDSDEKAKEILAQIKSEEISFEDAALKHSSCPSKDMGG
                     DLGTFGRGQMVPEFEEAVFSMAKGEVSEPVKTQFGYHIIKLEDLQESTESTFDEVKAE
                     VEKSLLYQKQNEVYGNKINALNAKYGNLVKYND"
     gene            complement(20885..21313)
                     /locus_tag="JAM15_02685"
     CDS             complement(20885..21313)
                     /locus_tag="JAM15_02685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAT6797182.1"
                     /translation="MNILFFLTPKSEVAYIYEDYTIRQALEKMEYHKYSAIPIISKDG
                     KYVGTITEGDFLWTLKNDLNLDLKGLEDVPVTDINRKMDNSPVSINADIEDLVIKSLN
                     QNFIPVIDDQDTFIGIIKRRDVIGYCYEIIRGYKNLANDN"
     gene            complement(21734..21934)
                     /locus_tag="JAM15_02690"
     CDS             complement(21734..21934)
                     /locus_tag="JAM15_02690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAT6797183.1"
                     /translation="MKTGVVKWFNNEKGFGFISVEGEGDVFVHFSAITGDGYKTLEEG
                     QSVEFEVVDGAKGPQAANVVRL"
     gene            complement(22117..23271)
                     /locus_tag="JAM15_02695"
     CDS             complement(22117..23271)
                     /locus_tag="JAM15_02695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase domain-containing protein"
                     /protein_id="HAT6797184.1"
                     /translation="MKILKNKNKYIKGIMAFVFLSLATTAGVFLINDLSMKNMEEKVM
                     ESANVEGDDVKDQYKLLLENLFDYRNKAILEKNENILKGLYETDKKFGLWAYENEVKK
                     MKYLENWSSKQGVKFKDIKTRVKIKKIKEKEKDLYGIICSVSTEYKYSYENQKDKENA
                     FRIGTYHYLNVKIIDNQYVITKEWYTDPFADSLNLENIKSEDIRNYIGQQDGVELQLT
                     DEQKKAIDYAHKYCGAAADEEHGMKFNPNYRDYNPEGGDCANFASQIMFESGRFKKNS
                     IWNYSERAGTKAWVNAQAFKNYALYSGRGSLIAKGSYEEVYKEAYNLRPGDFVGYEKK
                     GRITHVSTVTGLDSRGYPLVTCHNTDRMLVPWDLGWSDKSIRFHIIKINY"
     gene            23522..24343
                     /locus_tag="JAM15_02700"
     CDS             23522..24343
                     /locus_tag="JAM15_02700"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HAT6797185.1"
                     /translation="MQKKVAAINDLSGIGKCSLSVAIPILSALKVQCCPFPTAILSSQ
                     TGYPEFTFLDFTDEMVKYSNVWKNLKVNFDSIYSGFLGSKHQIEIVANFINDYPNAFI
                     VVDPVMGDNGVMYPIFTEEMRQEIKELVKHSDLTTPNLTEACFLTGNDYTKSDYNRDE
                     LIYIAKSVSDLGPSKVVITGILEDDNILNLAYDRDNDHVFFTSVKYNNCSYSGTGDIF
                     TSILCGMLVNKHDLGVAVNTATDFIYKTINYTSQFDTDRNDGVMFENFLSDLTNI"
     gene            complement(24419..25807)
                     /locus_tag="JAM15_02705"
     CDS             complement(24419..25807)
                     /locus_tag="JAM15_02705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase"
                     /protein_id="HAT6797186.1"
                     /translation="MLRSKKSNNKKVEKLRTIFIKYLSLFFVMTISFALLLMLSFSVL
                     LSSGVILPANYSEKQFDKYKEKIISSEKAIEDIIPNLYEYGVYTLDGNLISGTFNKKE
                     SKQVWNLMRDIEERHAYSESYIKFFKKDEVFIIKYKLVSEYSSPVLRAYLPKPEMLGM
                     IIFSIIFFIEIVILSKVFGKKFNIEMELLKNTTEKIEQQDLDFVVESSKIYEINNILF
                     SMDKMKLALKNSLEKQWMLEENRKEQISALAHDIKTPLTIIHGNTDLLIEINENPELL
                     EYMEYISKGVTQIEKYINTLIDISKTENGYILNKEAINMSEFIKDVLLQIEALASTKN
                     LDVEFYKQDNLPKNITIDRELLFRAIMNIISNAIDYSPSQSKLYISVSVSNKYLKFVV
                     TDCGSGFSKADLSKATEQFYTGDLSRNSKSHYGMGLYIVNNIVQKHNGILYIENSVKT
                     GGAMVTIEIPIV"
     gene            complement(25941..26699)
                     /locus_tag="JAM15_02710"
     CDS             complement(25941..26699)
                     /locus_tag="JAM15_02710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HAT6797187.1"
                     /translation="MRQLIRIFCSDLIKLKRNFIILMHICIALMGMGLFLWYYKVSGA
                     DNILKIVAYLQVIAIAFPLLSGVVCSMFVEQEYYAGNYKHMLTTSNPKYLTLISKYII
                     LVCLGFVATLVSVLGFKFGISKAYFASSFYMISILILIGCNLFEYILHLFLSLRFGKG
                     ASIGVGIVEMLLSALLLTGLGSGIWQYFPCAWGVRFITIWSSFSSSKTVEYIKVESIK
                     AYQSTGLMCGFVTILAFVILCIWFSRWEGKKSEE"
     gene            complement(26701..27417)
                     /locus_tag="JAM15_02715"
     CDS             complement(26701..27417)
                     /locus_tag="JAM15_02715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HAT6797188.1"
                     /translation="MERFIRVEFQKMKGTFGMKLIWIVPVFCILLCGLGGGQNAAFNW
                     WYTTFLPGALTLISSLIVLKDEKSKYRGILPLPIEMKDVWAGKMIYCIICCFIASIIS
                     AIGVVFVGIIYKETISIGQNIIATILIILLFMWQIPLCMFLASKFGIFVTVLTNMFFT
                     IVGVAVFSTTEMWYVFPYSIPSRLMVVVLHILPNGLPVPEGSELLNNAVILPGVLISV
                     ILFVLFALVTRAWFNNREVK"
     gene            complement(27419..28126)
                     /locus_tag="JAM15_02720"
     CDS             complement(27419..28126)
                     /locus_tag="JAM15_02720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HAT6797189.1"
                     /translation="MNNYILQVKGVSKKFKEQMAVDNISLAIKSNSIYGLLGPNGAGK
                     STLLKMITGILNPTSGKIMFEGHRWTRKDLSNIGSLIESPAIYENLTARENLKVHTTL
                     LGLPDSRIEEVLETVDLRDTFKKRSGQFSLGMKQRLGIAIALLNHPKLLILDEPTNGL
                     DPIGIEELRKLIRSFPKQGITVILSSHILSEVEQVVDEIGIISNGVMGYQGEVSKEQN
                     LEELFMKVVAENRKRGE"
     gene            complement(28243..28779)
                     /locus_tag="JAM15_02725"
     CDS             complement(28243..28779)
                     /locus_tag="JAM15_02725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HAT6797190.1"
                     /translation="MNKIAVSFLIIATTLLSTACMDYSISAVELVDSKESAVVKKDED
                     AKEETTSKMINSKKTTKIPIEIISKDEKIVKYLQIDEESSLKDKLRLILDTLSNEYFN
                     GLDMEVEVKEKDNLVKINLIEPDKKSRVSWKDDYLNEQNIIYTINNIIKNVIQEEDNS
                     IWIEEVEIYYNGKLIELR"
     gene            complement(28881..29951)
                     /locus_tag="JAM15_02730"
     CDS             complement(28881..29951)
                     /locus_tag="JAM15_02730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HAT6797191.1"
                     /translation="MNKKLAIFAAVLLVIGIIGTTWSGILVMPSLINFGLEKEAEFKK
                     ENKLYQEKVNIDKLDIAVDNINVTIKKSSSEDVRVTTRGNNEFYKYNVTLKDKTLVVK
                     GERKYENKIKKIKNFDQLLNTSINSMFSHDYREIIIYVPNNVDINASSISSYLFVYDN
                     VASNTITYKTSYGGFSRAITENKVNRLENLNLISNSNLHLSTKSILGVKNVNIESESL
                     DISSENEDVFINNIEEYIPENVNIKEKIGRNSNYESEFYLYSNMPIAKFLDIEVPNSK
                     VRLDIPVNKYKFNCDIKSKEVIEEFNNDEEYDNDSYDYEHSEEHSNKYRNTREIKGLL
                     NKNLSNLEKEYTIKINSNSLEL"
     gene            complement(29944..31002)
                     /locus_tag="JAM15_02735"
     CDS             complement(29944..31002)
                     /locus_tag="JAM15_02735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HAT6797192.1"
                     /translation="MNLNKTEFLEILKDYLKKDFSESEVNDILRDYEEYFVDGLIEGK
                     SDMEIIASLGSPKSIAKELILQTKEKNIEEEKIINTDVLNDKFSKFKSDMKKGYSILK
                     DEAKEKYSKSKENIDEKIMNTDILNGKFSRFKSNIKKDYSILKDEAKEKYNKSKENIN
                     DKLTPSIEEGVGGLSRQVIKGLLVVLSLFLIVPAFAFVCAIVSVTIALVCSLIAFVIL
                     IPFVIKFIAMVPDVMMFCIFATIAFVGLEILAWQILLFAIKLGKQLLNNYIHWIKRKN
                     IYIKANEKMEKRKKATLNDEDLNKDINEDSYNNDYYNREEESIKETDEYNDDSINFEA
                     IYKDLEDIENKKGEDKHE"
     gene            complement(30989..31321)
                     /locus_tag="JAM15_02740"
     CDS             complement(30989..31321)
                     /locus_tag="JAM15_02740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAT6797193.1"
                     /translation="MNTQFRKGVLEICVLALISKKDMYGYEIVHNISKVIDVNEGTIY
                     PILRRLTKDLYFETYILESNEGPARKYYRITSLGKENLSNLMEEWREFVKAVEILISE
                     DEGGNELE"
     gene            31520..32641
                     /locus_tag="JAM15_02745"
     CDS             31520..32641
                     /locus_tag="JAM15_02745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactosyldiacylglycerol synthase"
                     /protein_id="HAT6797194.1"
                     /translation="MKDDKTILILTAQFGAGHISAAKAVKECIIEKYSNYNVVIQNFI
                     NASIPMMNKPMVKLYENNTKYTPGLYNYYYYFKKSFDSRHDLSHKLYTPKLSEYIADI
                     NPDLIISTFPLAAACVNNFKIKNPDINIPTLTVITDVVDSMEWVFENTDLYFVPSPEI
                     KNRFFQKGINPDSIKVTGVPVDKRFQIESKELCCDKYRLLLLGGGRGLFDIDEDFMHW
                     IDEFIEEHSNSIEITIVTGKNKKLYDNLTHKKPLKNIKVLGFVNDMYNLIRECDLMLT
                     KPGGATIFEAIQSQTPVLVKMPKVGQEIENAKFIIDKGLGMIYSDDLDLKNIFYKLVS
                     NEFDSIINFMKKNLEEFKTVIHPEKIADYISELIDNHYS"
     gene            complement(32769..34667)
                     /locus_tag="JAM15_02750"
     CDS             complement(32769..34667)
                     /locus_tag="JAM15_02750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002846060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HAT6797195.1"
                     /translation="MDSLLYVIEKDKHTNEELREILKSNKNIRFVSLMGVDLGGNATD
                     EKIPVELFLEDIDKFLESAIQTDGSSVELYNIATLNNAKVDLMPDKSCHWYVDYNMEY
                     IDEEVGLPVGTLKIPAFLIHDNKKVCSRGVLQKADKYFKKSMYEIFREYPHVINNIGI
                     DSVDDIEEIMLTAATELEFWVNTPEDKADLEKLYVSQSLKEQYWKRTHGIIRTCLEKS
                     LIILQKLGVNPEMAHKEVGGIQSSISIDGRTNHAMEQLEVSWKFSTPLQAADNELLVR
                     DVIEDVFTSHGLEVTFKAKPIHGVAGSGGHTHVGVSAKLKDGSIKNLFAPKDLKEDYL
                     SELGYGALMGLLYNYEVLNPIVTASNDGFNRLVPGFEAPVCIVTSLGHSYEIPSRNRS
                     VLVGLIRDMKNPKTVRFELRSPSPLSNTYLVIAGCYQTMLDGIKAAAKSGLSTKELEK
                     ELSKNVGEESFYLEKDRAYRDENDVFEHYSLEERNARFGIPPATVYENMKNLEIYASK
                     LKSLKQGDVFTDSIIESFKIGAIDKWQKKLKTRIIEAGIQKIRSIVKIHTKENMDALD
                     EVVWNSISDLKFNIMKDTLTRESLFTRVREAIENKDYQTASDLQIELKRSMEEIQQLY
                     MQYKKNIY"
     gene            34982..35758
                     /locus_tag="JAM15_02755"
     CDS             34982..35758
                     /locus_tag="JAM15_02755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HAT6797196.1"
                     /translation="MEYIIFDLEFNQGFDKKLNKTVSNEKCPFEIIQIGAIKLDSKFN
                     IIDTFNSYVKPTIYKDIHPFISRMTNIKNSDFNDSPTFPEVYNNFIKFISSQDPILCV
                     WGVGDLKELYRNINYHKLPSSSLPKSYINIQQHASKYFNNPAGKSIGLQNAISILELD
                     EKMSYHNALNDAYYTAKVFIKIYNPSIVPDIYLYTSIKPKTIRYSNKKRVDYDKLFDE
                     FRKILNRELTKDEKKIINLAYNMGKTNQFTLENVKQRKNK"
     gene            complement(35850..36602)
                     /gene="xth"
                     /locus_tag="JAM15_02760"
     CDS             complement(35850..36602)
                     /gene="xth"
                     /locus_tag="JAM15_02760"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HAT6797197.1"
                     /translation="MKFISWNVNGIRACVGKGFLDFFKEVDADIFCLQETKLQEGQIE
                     LDLPGYFQYWNYAERKGYSGTAIFTKKEPLKVMYGINIEEHDKEGRVITLEFEDFYFV
                     TVYTPNSQSELKRLEYRTRWEDDFIDYLTKLDNHKPVIVCGDMNVAHKEIDLKNPKNN
                     MKNAGFTKEEREKFSKLLDSGFIDTYRYFNPDKEGVYSWWSYRFNARKNNAGWRIDYF
                     CASKKLEDRLVSADIHTEILGSDHCPVELEIK"
     gene            complement(36763..37713)
                     /gene="galT"
                     /locus_tag="JAM15_02765"
     CDS             complement(36763..37713)
                     /gene="galT"
                     /locus_tag="JAM15_02765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HAT6797198.1"
                     /translation="MKELRIDPITNDVVIFATDRLKRPLDTADIPNEDEETNEYDEEC
                     PFCKGNEAHATDALFEIESEEGWLVKSVYNKFPIIDDMARDVYGVHEVMIESDKHNRS
                     FYNMSQKEFEDVFFMYRNRFRDLSKDDKVEYVSIFKNFLRKAGASLMHPHAQILSMSF
                     IPPEITNELLVSKEYYDSNKSSLYDDLIENEISLDRRVVYNGEAFLVLIPYATKYSGE
                     VRIIFKDKIEFGELNDNNIQELSTIFEKLFKKLYNINGYMPFNLCIHTHPTKIETKSY
                     FNVHMHIIPRKYNFGGFELGTNMYVSSMSPEDLTKKLKID"
     gene            38098..39294
                     /locus_tag="JAM15_02770"
     CDS             38098..39294
                     /locus_tag="JAM15_02770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAT6797199.1"
                     /translation="MNYSNRVSAMQASPIRKLVPFAQAAKDKGIKVYHLNIGQPDIKT
                     PKGFFDAVKNFDSEVLEYATSEGIPELLEALQNYYKTYDMNFEKDELLVTNGGSEALL
                     FTMMAVCDPGDNLLVPEPFYTNYNGFGQSVNVEVNAVTTKAENGFHLPSKEEILSKVD
                     DKTKAIILSNPGNPTGAIYTKEELNILAEIAKEKDLWIIADEVYREFVYDGLEYTSCG
                     NLEGVQDRVIIIDSVSKRYSACGARIGSIACKNKGLIAQILKLCQGRLCVPTLEQIGA
                     VELYKTPVSYFKEVNEEYKKRRDVLYNELMKVEGVICKKPTGAFYIVAKLPVENAEDF
                     TIWMLKEFNKDNETVMVCPAEGFYATPGLGRDEIRLAYILNEKDLHRAATLLKEGLEQ
                     YVALQK"
     gene            complement(39406..40746)
                     /locus_tag="JAM15_02775"
     CDS             complement(39406..40746)
                     /locus_tag="JAM15_02775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HAT6797200.1"
                     /translation="MKKRYNIAIVGGGSTWTPGLLKSLCKMSDRFPLNKVTMLDVVEE
                     RQRLIGEFGKILFKEEYPKATLEYTTNPDEAFIDVDFVFVQMRTGGLKMRELDEKIPL
                     QFGLVGQETCGAGGFAYGLRSIGDMIEMVKTVRKYSPKAWILNYTNPAAIVAEALKRV
                     FPDDKRLLNMCDQPVNLLRSYGRLLDMDSRTFEPVYFGLNHFGWFTHLYDKNGEDLVP
                     KIKDLVANSGFQPVDAEQRDKSWLDTYGMVKDMLEDVPDYLPNTYVQYYLYPDKKVAK
                     SNINCTRAREVMNGREKRVFEECKSVIEKGTSIGSNLVHNDAHGEFIIEVAEAIAHNK
                     HQIAIVITENNGAINNLPDDAMVEVAAILTKNGPRPLHVGNIPTFYKGLLEGQLAYEK
                     LAVDAYFEQSYEKAILSLTLNRTIISPTKARQVLDALIKVNKDYWPTLYKENEK"
     gene            complement(40885..41637)
                     /locus_tag="JAM15_02780"
     CDS             complement(40885..41637)
                     /locus_tag="JAM15_02780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAT6797201.1"
                     /translation="MNLIDKLDINQKKLSTNEISLLNYFLKNSEKINQKKIKDIANET
                     FNSTAYIVRFCQKLGFSGYSEFKNFLVFSYSNRNERNKEFTKSQSDIFTDVMDTQNLI
                     NVENIDMCLNEIHNSKHIYFFGVGSSRLVCTEMSQRFSAIGVNVKYYDDSTLMYLAAS
                     NITKDDLVIAVSMSGETAQVIKACNIAKTNQVKVISLTNISVNSLSNIADIKLFVSSP
                     QYNFNSVNYTSRVPALSLMEYMFHKYIEKYNR"
     gene            complement(41796..43373)
                     /locus_tag="JAM15_02785"
     CDS             complement(41796..43373)
                     /locus_tag="JAM15_02785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAT6797202.1"
                     /translation="MKQKMKEFFLQLGKSFLLPIALISAAGIFLGISSAFSNPNIVSD
                     IPFLENNFIQGILGFTKAITGVLFGNLAIFFAISISVGLAKEEKAVSAFSGFVGYLVL
                     HTSVNYMLGCRGILAEPDMMREMGQAVTLGIQTLELGVFGGIVVGIITASLHNKYYNI
                     KLPDYLGFFGGTRFVPIITTVVFSILGIIIPYIWPYVNTIIQSVGIGIASLGYLGTFV
                     FGFLERLLIPFGLHHILNAMFRFTEVGGSLVVGGQEVFGALNIFLAQLSDPETISFST
                     EATRFLAQGKIPIMVFGLPAAAYAMYKTAKPENRSKVKGILLAGALATFVTGITEPLE
                     FSFLFVSPILFVIHAFLSGISFMMMHIFGVAIGNTQGGIIDLVVFGVMQPNTKWIYSI
                     ILGLVYALVYYNVFKVLILRFNLQTPGREEITDINFDLEPLSNKVEIAQSGETTKRAL
                     SIIKYLGGKENIEDITNCITRLRVVVKDMSKVDESAFKKYTGAMGVIKVSDKDIQIIY
                     GPSVSQVRDEVSFAMSI"
     gene            complement(43786..44238)
                     /locus_tag="JAM15_02790"
     CDS             complement(43786..44238)
                     /locus_tag="JAM15_02790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAT6797203.1"
                     /translation="MNYIVKDTISFLVKTFPKIYSSLYLEDLKKFAPDYNVNKTQLRA
                     LVFIKNYGVISMTDLCSKLNIEKGSLTSMVDDLTDKKYVTRKRDLVDRRKYLIDITEE
                     GDKIATDFMDKLSDGLGEKLSKLTEEDRKKYLEAINTLQYILNKEEFR"
     gene            complement(44549..45994)
                     /locus_tag="JAM15_02795"
     CDS             complement(44549..45994)
                     /locus_tag="JAM15_02795"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HAT6797204.1"
                     /translation="MIDNKYTTYSNPLTDRYCSKDMSYIFSPQFKFSTWRRLWVALAE
                     GEHELGINITEEQLDELRANIDNINFDEARKIEKEVRHDVMSHVKAYGLQCEKAKGII
                     HLGATSAYVGDNTDVIQMNEALKLLRVKLVNLINNLKEFALKYKDMPALGFTHFQAAQ
                     LTTVGKRACLWAQDLILDLEDLNYRIDNMKLRGVKGTTGTQASFLSLFEGDHEKVKEL
                     DKKICKKMGYHSSYAVSGQTYTRKLDYQVISILSGIAQSMHKMTNDIRLLQSLKELEE
                     PFEKNQIGSSAMAYKRNPMRSERIASLSKYIISESISPAMVQATQWLERTLDDSANKR
                     LAIPQAFMAADAILEIGINVTDGLVVYENMINKRVNEELPFMATETILMEAVKRGGDR
                     QELHEIIREYSMKAAYRVKHEGKDNNLIELIMNDDSFKMSKEEILSIMDPKNFIGRAP
                     EQVVEFVNEVVEPAIKDYKEDLGKVDVDLRV"
     gene            complement(46138..47046)
                     /locus_tag="JAM15_02800"
     CDS             complement(46138..47046)
                     /locus_tag="JAM15_02800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAT6797205.1"
                     /translation="MYSTKILDDYEYETFNVFSTKLNPNTKHDYLSKVILFKEFLKGK
                     ELIYATKEDCKNFVDYIQTKYAKSTCEKIYSYLHSFYNFLKKEGYIDINPFRYVEKPT
                     VTRIKTKDDVLSIQEINKLIGILPKLNIRDRVIIVCLVTTGCLLNELVSLKWKDLMVD
                     ENDNSYVRLGKGRKERVVKLHPYFFKLLEDYRNYSGLPEVIIPSDDFIFTTQKSNSIT
                     DRNVRLIVKKALDLAGLSQYSARDFRHSFAAISLRLGADESDVKNQLGWSDKYYAIRY
                     KYVLNFVDSEIVDYLIEKDNLDINKK"
     gene            47303..48127
                     /locus_tag="JAM15_02805"
     CDS             47303..48127
                     /locus_tag="JAM15_02805"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HAT6797206.1"
                     /translation="METFSLLEIFKAVILGIVQGITEWLPVSSTGHMILVDEFIKLNF
                     SNTFISTFLVVIQFGSILAVLVIFFRKLNPFDSAKNIKQKKETVRLWLKVIIAVIPSG
                     VIGILFEDDIDRLFFNSTVVAIALIVYGIIMIGLEKRNKRPKYKDFSQVTYKLALCIG
                     LFQCLALIPGTSRSGSTIIGAVLLGTSRYVAAEFSFFLAIPTMLGASALKLLKAGFGF
                     TGFEWLILGVGSVVAFVVSIVVIKFFMDYIKKHDFKVFGYYRIVLGIVVLAYFFLL"
     gene            48149..48697
                     /gene="lepB"
                     /locus_tag="JAM15_02810"
     CDS             48149..48697
                     /gene="lepB"
                     /locus_tag="JAM15_02810"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAT6797207.1"
                     /translation="MIRRKVMSVKKEIFDWIKSIAMAIVLAFVILQFIRPSIVSGESM
                     YPTLDDKDYLILNRISYKVGKPEKGDIVVFKTNLVDGETGKKKDLIKRVIATEGDRIK
                     ISNSKVYVNGKLLNEPYIHNNYTSGDIDTVVPKGKLFAMGDNRENSNDSRFPDVGMVD
                     EDEILGKVMVRLLPLDNIGKVD"
     gene            complement(48779..50560)
                     /locus_tag="JAM15_02815"
     CDS             complement(48779..50560)
                     /locus_tag="JAM15_02815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HAT6797208.1"
                     /translation="MSQYININSQLDALKLKEFEKIFYENINEDVKVVPKVTPFKGIN
                     TDLLYVKDGRILFIKFMDTTEDIFFILEEELLEVMNEEYELLKLKMGQKNRNISYNYV
                     YIMPYVEVEETYEFEEFVNNNIIDKNKLQDIMNKGSLEEYLNDENDEINLNLFLLDIC
                     SEYYIINDKLHLNEKFKKISFYNDDYKYTATMMEDVQIKDVVSIKYGNTLIEGGSGIG
                     KTAIMLSRAIKLAKVYPHHKLVIFTHTKQLCNELRERIELLYKDNNNLEVHTFSSFIF
                     KLAKKFNLIVDYNMLKNDYEKTFNNLVKQAQNIIKNKNMFKAIFIDEAESFLEYEIDF
                     IREFLYKTKFIFNACSCNSLNISNRLNIFKKLYNGIEFDDKIILSKNYRQAKEIVDFT
                     NKFSNNSNSYINELRPNTEFSTFFYTKALRGGNKSVDIIKVSDLDDQISSVIWEIEYL
                     ISKKGLDYSEVAIVYPYNKKKLKSGKTIYFQYMLKKALEEAKIPYICAEDNLTNISKK
                     VGTTIANIYAIKNLEYKAVIVCELEMLYNQTINDIEQDYQVNDFVGDLNKVYLAMSRA
                     TDYLSIVTTFNEEASDIIRLITESKDI"
     gene            complement(51195..52736)
                     /gene="rny"
                     /locus_tag="JAM15_02820"
     CDS             complement(51195..52736)
                     /gene="rny"
                     /locus_tag="JAM15_02820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HAT6797209.1"
                     /translation="MDVIDSVVMIVIGAAVGIIAGYFVRKNISEAKIGQAENLAKEII
                     DKAHHDSETVQKEKLLEAKEEIHKWRTEAERENRERRTEVQKYEKRVVQKEEVLDRKL
                     QNLESKEVNLSEKLKVVEKKEEEVEVIKTQQLEKLESISGITSDKAKEIILTNAERDV
                     RREMSIMIKEIESQAKEEADKKSREIIGYAIQKCAADHVAETTVTVVSLPNDEMKGRI
                     IGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARIALEKLIADGRIHPAR
                     IEEMVEKARKEVDNIIKEYGEQAAFETSVHGIHPELIRLLGRLNYRTSYGQNVLKHSI
                     EVAHIAGIMAAEIGADIRLAKRAGLLHDIGKAVDHEMEGTHVEIGMDLLRRYKESKEV
                     IHAMSTHHGDYEPQTVEAVLVTAADAISAARPGARRETLEAYIKRLEKLEEIANSYEG
                     VEKSFAIQAGREIRIMVKPEAINDEEIHLLARDMTKKIEDELEYPGQIKVSIIRETRA
                     IEYAK"
     gene            complement(52912..53958)
                     /gene="recA"
                     /locus_tag="JAM15_02825"
     CDS             complement(52912..53958)
                     /gene="recA"
                     /locus_tag="JAM15_02825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HAT6797210.1"
                     /translation="MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTG
                     AIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSCVASAQKDGGIAAFIDAEHALDP
                     VYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
                     GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKF
                     YSSVRLDVRKIDTIKQGDKVIGSRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLL
                     DIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTTEIDEKVRAFYNLNEEH
                     EESGTSVSKEIVEE"
     gene            complement(54246..54788)
                     /gene="pgsA"
                     /locus_tag="JAM15_02830"
     CDS             complement(54246..54788)
                     /gene="pgsA"
                     /locus_tag="JAM15_02830"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HAT6797211.1"
                     /translation="MNLPNKLTLFRIFLIPVFVLIMLLNVPNKFLIACIIFIIASITD
                     ALDGKIARKYNLVTDFGKFMDPLADKLLVISALTCMIEDHLVSSWMVIIIVARELTVS
                     ILRAIAAADGKVIAAGNSGKLKTITQMVSIVFLLLGAQFENVLILNIGEILILIATLL
                     TLYSGWEYLYKNKELFMSSK"
     gene            complement(54775..56109)
                     /gene="rimO"
                     /locus_tag="JAM15_02835"
     CDS             complement(54775..56109)
                     /gene="rimO"
                     /locus_tag="JAM15_02835"
                     /EC_number="2.8.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="HAT6797212.1"
                     /translation="MLKIALESLGCSKNLVDAEIMMGILNNKGYKLIGDFEEADVIIV
                     NTCGFIESAKQESIDTIINFSELKKTGNLKLLIVTGCLAQRYSEELKTEIPEIDAIVG
                     TGSYQNIDKILKELSEMHQIVSLNDIEFVFNEDLPRYISTPSYMAYLKIGEGCSNNCT
                     YCIIPKLRGKYRSRKFEDIIKEAKKLAESGVKELVVIAQDTTKYGFDLYGKERLSELL
                     EELAKIDGFKWIRVMYSYPESITEELIQVIKKYDNICSYFDMPIQHASNNILKLMNRK
                     TTKEDILNKINLIRSNIPDAILRTTIIVGFPGETEDDFKQLVDFVEEVKFDRLGAFAY
                     SREEDTPADRLPNHIDEEVKIQRRDTLMMIQQKISEELNDKKIGKTYEVLIEEQIEDN
                     VYTGRTQGDAEEIDSIVYVKSVDNLEVGEFVSVQINDAMEYDLMGDVLYELA"
     gene            complement(56103..57161)
                     /gene="mnmH"
                     /locus_tag="JAM15_02840"
     CDS             complement(56103..57161)
                     /gene="mnmH"
                     /locus_tag="JAM15_02840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-selenouridine(34) synthase MnmH"
                     /protein_id="HAT6797213.1"
                     /translation="MSVIKIEKALKLDKVIFVDVRTEGEYEEDHILNAINMPLFKNNE
                     HNEVGTIYKMQGKHEAIQKGFDYVSYKLKDIYLQAAELALNYDNIVIYCARGGMRSGS
                     IVNLLSSLGVNVYQLEGGYKAYRNFVLEYLRHVMDTKNFVSVHGLTGTGKTDLLHLLD
                     EKGIDVLDLEGIAKNSGSTFGFITFDKKPPSQKNFETKLFESVFFSKENYIFVESESK
                     RVGSVTVPNEIFEAMTREGHHILLECDIENRVDRLCRDYIYDKDEGNILILKECINKF
                     RKRLGNKVVDDYIDLLESGEYKELVKRYLLEYYDPLYMHSVEKYKYSKIINFNDTQKA
                     LEDVIDLYESILEGESEC"
     gene            complement(57164..59575)
                     /locus_tag="JAM15_02845"
     CDS             complement(57164..59575)
                     /locus_tag="JAM15_02845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HAT6797214.1"
                     /translation="MATKKKKKKKVNTLSFNAEYHNLITIFIGVFLLYSLNSNSMGWI
                     PVLMQNLFKGLFGGLSIAIPFIVIITGLLGFFDGNEYIYRLRKTKLYYIIILFIFVFY
                     GLLNAGTLPVDSPLKGNMFDDVMKLGVSGQGSGLIATTIAYYMSKIFGIAGGWLISIF
                     ALILSVMFIFNISIKDLVSNAKSKSKASKDSNLTFKDKIANMKKSAIDMMTDEVDDTT
                     INKKPGFFKGLMSKGLNNDDEEDEYFEEENSDGVDDKTIKIVGFNKAEDEYLEILEGT
                     QSMPELDVLKELQKATNENPVVDTKPEKKVDIAKSNLNIEKTQPMSIVAEPVNEDYSN
                     YKKPSIELLNKVNKKSDENGKKKVLKNASLLEKTLSDFGVEAKINQVTVGPTITRYEI
                     QPSPGVKVSKIVNLTDDIALSLAAKSIRIEAPIPGKSAIGIEVPNEEAQMVGVREVLE
                     SEEFNNFNSPLAMGLGKDVAGKIIIGDIGKMPHLLIAGSTGSGKSVCVNTLISSILYK
                     ANPDEVKLLLIDPKVVELANYNGIPHLLIPVVTDPKKAANALNWAVTEMNRRYKLFAD
                     AQVKDVTSYNEKAEEKLPKIVIIIDELADLMMASANDVEDYICRLAQMARAAGMHLIV
                     ATQRPSVDVITGVIKANIPSRIAFAVSSQTDSRTILDMGGAEKLLGKGDMLFYPLGAA
                     KPVRLQGAFISESESEKVIDFVKSQVKDGIKYEEDIIETISKVNTSKSSDDDEFLSEA
                     IEFVVESGQASASMLQRRFKIGFNRAARLIDSMEERGIIGASEGSKPRKVLISKQDLQ
                     NLEGE"
     gene            complement(59698..60432)
                     /locus_tag="JAM15_02850"
     CDS             complement(59698..60432)
                     /locus_tag="JAM15_02850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease"
                     /protein_id="HAT6797215.1"
                     /translation="MKDYREDNERFDKDNCSEESSCEERECIKQFGTNEMPPQPPKDI
                     QCITIIGEIEGHFIGNPQKKATKYEHIIPMLYSIEESNDVKGVLVVLNTVGGDIEAGL
                     AIAELLNSTSKKVVTLVLGGSHSIGVPLATAGDYSFIAPTATMIIHPVRTTGLVIGIN
                     ETFEYFKKMQDRIIQFIIRTSNIKKDVLEKLMHEKDELVSDVGSVLIGKEAVDYGLID
                     EVGGLKEALKKLRELIKESEEEKNND"
     gene            complement(60545..61768)
                     /gene="dapG"
                     /locus_tag="JAM15_02855"
     CDS             complement(60545..61768)
                     /gene="dapG"
                     /locus_tag="JAM15_02855"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HAT6797216.1"
                     /translation="MSILVQKFGGTSVESYEKMNEVCKIVKAYKKNDEELQLVLVVSA
                     MGRKGAPYATDTLINLCSAVNDEPSKRELDLIMSCGEIISGTILANLLNAQGIDSVLF
                     TGQQAGIITSDEYSNAKIKYINPKKVKRALDDGKVVVIAGFQGVTDDGEITTLGRGGS
                     DTSAVAIGKALECETVEIYTDVDGIMTADPRVEPNAKVLSFIDYEEVFQMADKGAKVI
                     HPRAVQLAKSGNITLAIKNTMNPTFEGTKIGSLCRHLEDNIEYEQERDFKVAVANKDS
                     VAQVKIKSAEEVFTEVLNEIEKKLITIDMINFFISEKAFVVEDADIKSLKEILDKFEL
                     DYEVNRDCAKVTLICSRIADEMSGIMSKVVRGLSKAGVSLLQTSDSNMTISCLVSEED
                     MHTAVHAIHQQFYLK"
     gene            complement(61778..62023)
                     /locus_tag="JAM15_02860"
     CDS             complement(61778..62023)
                     /locus_tag="JAM15_02860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HAT6797217.1"
                     /translation="MNLSEIAGKEIVNLVTGERLGVIGECDLILDETTGGILALLIPK
                     EKGFFARRKDKSFLEVPWRNVKKIGNDMIIIEYEGYI"
     gene            complement(62058..63305)
                     /locus_tag="JAM15_02865"
     CDS             complement(62058..63305)
                     /locus_tag="JAM15_02865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HAT6797218.1"
                     /translation="MYKTKILENGLTIIGEEIPYLKSITLGIWINAGSRIEEAQVSGT
                     SHFIEHMMFKGTKNRTSKEIASSIDNLGGQINAFTSKECTCYYVKLIDEHIDTGIDVL
                     SDMILNSKFDKNDIDKERLIILEELKMYEDSPDDLSYDLLVENIYANDGLGMNIIGTK
                     ESLYNITRESMLEYLNKYYIPNNAVISIAGNFNFDDMVEKIKSKFGHWEKKILSIDIS
                     EAKFNPCFISKNKDTEQVNLAMCLKGIPFENDEEVYSMAVVNNIFGGSISSRLFQKIR
                     EEKGLVYSIYSSQTLYRKCGELGIFASMSTENLQDVYNLIKKEIENIRENYLTEKEIS
                     ESKEQLKGNYILDLESTSSRMMSTGKSMLLSKKVKTTDEILECINNVNINSIKKIVDK
                     VFNIENIGTCIVGRDVEKILHLD"
     gene            complement(63463..64206)
                     /locus_tag="JAM15_02870"
     CDS             complement(63463..64206)
                     /locus_tag="JAM15_02870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HAT6797219.1"
                     /translation="MIMMVLNKSKLKKIIILILVVLLVLSGGVMVLKLFNNKPVFNLF
                     NGVDLPYERGTKDKSGYVALTCNIDLGWETEYVESILETLKKENVKITFNVTGKWAEK
                     NKDELLKIKKQGHEIGNHGYKHLDYSTLSYEDNYEQIETSKKIIEEIIGEKTKFFQAP
                     AGSFGPETVKAAKALGYTSIKWDADTIDWKYKDQPEAIIDRMKKKDIKDSSIILMHPT
                     NATTKCIDDIIAIVREKGLKPGKLSDVFK"
     gene            complement(64472..66583)
                     /gene="pnp"
                     /locus_tag="JAM15_02875"
     CDS             complement(64472..66583)
                     /gene="pnp"
                     /locus_tag="JAM15_02875"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HAT6797220.1"
                     /translation="MFEHKIFKMDFAGRELSVEIGKICEMASGSCIVRYSDSMVMVNT
                     TKSAKPRDGIDFFPLSVDYEEKLYSVGKIPGGFLKREGKPSEKAILTSRLIDRPIRPL
                     FPKGFRNDVQVVATVLSVDQDCTPDIVAMIGSSIALSISDIPFNGPTGSVCVGLVDGA
                     FVVNPNAEQREKSSMHLVVSGTKEAIMMVEAGADEVPDEVMLDAILFAHQEIKKIVEF
                     IEGIVAEVGKEKMPVELYHAGEEITQLVREFATDKMKKAVQTFEKLERMENMDRVKEE
                     TLAHFEETLEDFEDFVGDIEEVLQDIIKEEVRKLIVHENVRPDNRKLEEIRPIWCETG
                     MIPRAHGSAIFTRGQTQVLNVATLGALGDVQKLDGLDEEENKRYMHHYNFPAYSVGEA
                     RPSRGPGRREIGHGALAERALLPVIPSQEEFPYAIRLVSEVLSSNGSTSQASVCGSTL
                     SLLDAGVPIKDMVAGIAMGLIKHDGKVAVLSDIQGMEDHLGDMDFKVAGTEYGITAIQ
                     MDIKIDGIDKEILQRALKQAKEGRIHILGEMRKTISQPKPELSPYAPKIVKMQINPDK
                     IKDVIGPGGKIITKIIDETGVKIDIEQTGEVFISGIEIDMIKKAQELINNIVVEPEVG
                     KTYKGKVSRIMNFGAFVEILPGKEGLLHISHIAHERVAKVEDVLNIGDEVEVKVTEID
                     EKGRVNLSRKVLLPKPEHKNK"
     gene            complement(66708..67553)
                     /locus_tag="JAM15_02880"
     CDS             complement(66708..67553)
                     /locus_tag="JAM15_02880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAT6797221.1"
                     /translation="MKIKLVCDSLCDIPDEISEKDYIEIVPLTVIFNDREYIEGVDIK
                     KEEFYKKVKEIKQIPKTSQATYMEFKEVFDKFITEGYHIICMTGAANASGTFQSAMIA
                     KNDVNENEKIHIFDTRNLSLGSGQYVIKACELLEEGLGFEEIIDELENTRSSVRLLFA
                     PYTLDFLKQSGRVPVATALIGNMLNIKPIFFFDNGEAKLVNKVRGIKNIASKLVDIIL
                     EMNEGSLEGKIVTIGCGDNLHDCEILKDEVNKRIKARRVLFTRGGVSICSHTGPDILA
                     ISCSN"
     gene            complement(67793..68050)
                     /gene="rpsO"
                     /locus_tag="JAM15_02885"
     CDS             complement(67793..68050)
                     /gene="rpsO"
                     /locus_tag="JAM15_02885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HAT6797222.1"
                     /translation="MINKSEIIKEYGRAEGDTGSPEVQIALLTARINELNGHLKTHKK
                     DHHSRRGLLKMVGRRRNLLAYLKEKDLEGYRALIAKLGLRK"
     gene            complement(68154..69083)
                     /locus_tag="JAM15_02890"
     CDS             complement(68154..69083)
                     /locus_tag="JAM15_02890"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HAT6797223.1"
                     /translation="MVIIKSIKEIANIKESVITIGNFDGVHKGHQVLIGKTVEYAKKE
                     NIQSIVFTFANHPVNYFRPNSTKNIISNDDKIKLLEDLGIDIVVIIPFDEYMTKIPAK
                     DFVDEILVKKLKAKKIVIGHDFTFARAKEGNVNLLKSLEHEFGFEVEVIKPIKINDVR
                     VSSTYIRSLVSQGDMANVKEYLGRNYKLEGCVIHSKHLGRTIGFPTANIDLKNNMLVP
                     KRGIYASIVHIGDETYFGATNVGYNPTVNGKTLSIETNILEFDRDIYGENIIVEFLER
                     IRDERKFNSIDDLKNQLYNDTNYVYENYVCKNK"
     gene            complement(69214..70119)
                     /gene="truB"
                     /locus_tag="JAM15_02895"
     CDS             complement(69214..70119)
                     /gene="truB"
                     /locus_tag="JAM15_02895"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HAT6797224.1"
                     /translation="MNKIISILKPTGMTSHDVVSRVRKILNIKKVGHTGTLDPDASGV
                     LPICIGKATKVCEVILNKDKSYICELTLGISTDTYDASGEILKKVDDFKFSNEDIERA
                     FDTQRGEINQLPPIYSALKVNGKRMCDLVRSGRQSEITLKTRRVNIKDIKILSIKGNK
                     VMFYVECSKGTYVRSICHDIGEYLGCGAHMSFLNRTSSGKFDLDNSITLEELELFYEN
                     KTLDKYLYDIDYVLDSFNYVVLNPNAIKYYSNGGSIDDKRFLKNNFDKDDEVVRVYST
                     DNFLGLGKLSKHNNTISVKSDKMFI"
     gene            complement(70132..70437)
                     /locus_tag="JAM15_02900"
                     /pseudo
     CDS             complement(70132..70437)
                     /locus_tag="JAM15_02900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438308.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
BASE COUNT        22440 a        12223 c         7578 g        28250 t
ORIGIN      
        1 atataaaatc cttctcaata aaatagggca ctatctacaa tactacttta tcttttccta
       61 ataatatata atctggtgct actgctactt tcatgttata caccgttttg taacatacct
      121 tttatatcag taacatcttc cttaatttcc tctacatctg ttttcattat tcccatttga
      181 acaagtatat ttttgtttat ttcttgttgt tgtgtagata attctataaa attttctaca
      241 gtttttttat acatgtctct atcttctttt ttctcctgca tagtattttt aaataataga
      301 gcacatagta tacctattgc ccccagacta ctcaattcgg ttattaattt atccattata
      361 gcctcctatt gtctaaattt tttatactta tagctttaat ttttgttata ttcttacatc
      421 atgcaatatt atattttcag gattatcaat ttaatcttct gtactttaaa ttgtaggttt
      481 aatttataga ttgaataaat aataaatata tatacaattt ctaatataac aaaaaataag
      541 tacaaggctt acttattaaa gttaagacct tgtactttac ataaaaaaaa taactaatac
      601 atagttattc taaatttact attcaactgg tatttctaat tctttacatc taattctaac
      661 ttgctctcta attactgctg gtacttcttc tattgttttt ctgcctctta aaattaaagc
      721 tacatatact tctaccattc cactctcacc tccagatttt cttacactaa aagtgcttat
      781 attacttgct tcattgacag aactttgact taacaacatc tcatatattt ctgcatttgc
      841 tataaaatta tttgttatat catcatcttg ctttgcttga cctatactta tgtctgaaat
      901 gtctttatac tgcatttcta cttttctacc ttgtttgatt tgttctattt tatttttatc
      961 gaatttaaac aattttcaca cctccatttt aagcttgtgg ctcgttgttt tcagcatcat
     1021 atctaaaaat catagatgga cgttttatag ctgtccattt atctcctttt tctactatga
     1081 ttttaggctg agcacttttt atgttggctt cttctaattc atagatttct tgataacttg
     1141 agtctgattt tttgatttca actagtttca tgtctttgaa taagtcagat ttatttattt
     1201 ttacttgaac tttagtttta tttattaatt gatatatagg attgttttcc atcatatcat
     1261 cctttaatcc ctcatttaat gttactatta agtcagtgtt attttcagta atgtttatga
     1321 ttgaatatac tttattgttt atcattaaaa tagaatcctt ttttacttta agccctgttt
     1381 ctgatttaaa tataaacata cttgaatata aatcacctgt aggactactg gctttaatca
     1441 gtatcttatt ttctcctaat actattttat tttgtggtat ctcaaatata atgctattta
     1501 tttccaaatt agtcttagta gatattaatt catcatttat aaacatttca agtttttcta
     1561 taacattatt agggtcttgt actacaactc tcacttgaga tattgatttt tcaactattt
     1621 ctatagatgc tttacttgta tctacttttg ttatcatgta tattgtatca tctgaaagct
     1681 ctatatctaa aatgtcattt agatgttcag gaactggtat tttagtaaat tcatataaat
     1741 cagtaattga tatagatatt ttatacatag atttattttt accagttatc catagactat
     1801 tatcattttt aattactagt atgtggtcat cattatgtga cttaatttct ttaacattag
     1861 ttaatacttt agtaaaagtt gttattattt tatctttttc actttctcct agtccaaaca
     1921 atccatttgt attataccct tgagcgtaca actctccctc attagttaaa acaagtgtca
     1981 ttgagttata tatacttata tctttaacag aaggtaatcc agtaaccttt tgtaactctc
     2041 ttacatcatt attgtgacca actcccaatt ggtactcagt attctttcca tatgaccata
     2101 gagtattatc tgtcttaata atataggagt agttatctcc acaagcaact tttttgacat
     2161 ctgatatatt tacttcagta aaagttaata attctatatc ttcaagagtt tgattaattt
     2221 ctttatatga attacttcct attccatata atttgccatc cttagcaaca gccaatgaat
     2281 gtgtttttga tatatcaata tcagatacct caaatggcaa tattattgaa gtatacttaa
     2341 aattatcttt aaatatgttt ttataattta tatacttatt atttgttttt atatacttat
     2401 cattaaacat tactagcttt tcatttttct tattaaaaac tattttatct gatgtgtcat
     2461 ctgttttaaa atatgaatgt agggaacctt caagagcttc atttttatca ttatcatatc
     2521 tatggtgaat acctaaatga ttatatctgt tatctcctgt tgaagaataa aattttccat
     2581 atatatcttt aataaatata gtattgtaac tagaaaatac agtatcaaca tctttcttta
     2641 tagatacttt ataatatgga actgacatat ccctataata ttcatcagat ataccataag
     2701 tatctctacc tgatgatatc aaattgttat tattatctat ataaagtgta ttattagctg
     2761 ttacaaaaac atctttaaca tcttccacac tatttgtatt attattattt gctatacttc
     2821 catatccact aagacctcca acaaatagtt tattgtcatt tgttaaaatg gctgaagtat
     2881 atccattaac tactattttt tttgcattta taatattatt aattactcgt atccccttta
     2941 tatcattagt ctctgttgaa aagaataccc tctctttttt ccctgtagta taaataacat
     3001 tatcatttgt tataaaaaat gtagcttcac ttcctgctgt cacaacagat tttacattct
     3061 caatatttat ttttgtaaat gtacttatac tactttcagt gaatccaaaa tatccattta
     3121 caaatccaca tacataacat gtattatcat ttttgacaat gattgataca tcattacata
     3181 gatatacatc tctaacacca tttataggta tacgtgtaaa tatattccta cttgtagtat
     3241 cacccaatcc taactgtcct tttccattat tacctgctcc atataaaaga ccatcattag
     3301 ttaataatag agatgtgttt ccatatacag ctacatattt tacattttca acatttattt
     3361 tagtaaatac atttctattt acattatctc ctattcctaa ctgaccagaa ttatttaaac
     3421 caacagcata acaggtatta tcatttttta tcgcaaatgc atgtttacta ttgtcagtaa
     3481 atctatttac atttatagat tttatattat caatatttat tttagtaaat acctttctat
     3541 ttatctcatc tcccactcct aattgaccta catcatttaa accaacactg taaatcatat
     3601 tattattagt taataaatat gtagactttg aatggctata tatttcttgt atattagaag
     3661 atatttcact actgctattc tttttattgt aatttatctt attatttaaa tttaaactac
     3721 tattaactga tataccatgc gtacccttag aattatatcc acatataaat aagctcttat
     3781 cagttaatat tgcaaatcta gttttatctc tacttaaatc ataaggaggt ataaatatat
     3841 tttttatatt tttcattacc tttttatagt tagttgcatt atatccatct tgtgtatctg
     3901 aaacatctag ttcttttgca ctttcagata tattcccaaa accatatagc gtgttagaag
     3961 ataaatacaa tagagcttta tataaaaata tggctttatc agaggtaata ggacctgaat
     4021 ttatattaga tgctgcaata ttattagatg attgattgtt aagataattc cttccatatt
     4081 gatgtatata agatgaacct ccagaaataa gtaaattgtc tggattatag ttttttaaat
     4141 tacttgatga ttccccatag tataaataag caaaatttgt agaataagaa gattgtgtac
     4201 atcttgtagg ataataatta tatacatagt tctcaacaca tcctgcatat gaaattcctt
     4261 gatgctgaac tttataattt gaatcagttg gttttatcca tctagtacca tgatatccag
     4321 ttaaaaaaga accaatgttt gtacaaaata tagttacata ctcatatata ataatattat
     4381 taattttagt aatatcattt gcacatgaaa tcacactata acttgttcct ccaggattta
     4441 tataactcca tgtacttaat aatcttaaat ttgtagtata tgtttcattg tttacattaa
     4501 ctcctaacat ataatttgta tttataccag ttgcatatac ctttttttca tcagcaacaa
     4561 taaatgttgc attatatgaa ctatatgcat ctgttacatt gctaagacta atctcagtat
     4621 attggcttgc tgatatatta ctaagtccat taacataggt tgagctcttt ccagaagtat
     4681 atatttgctt attattagtt acaattaatg aaaaccagtt tgataaatca gtatttataa
     4741 caactttttt tacattatct atagatattt tcttaaatac atctgaatta gaaggaagaa
     4801 cacctgctat tgagttacta tttggtccag aataataaca agtgtcatca tttttaatgt
     4861 agaatattcc tccagaaata ttttttgatg ctactataga ctttacatta gagatactta
     4921 attttgtcaa ctcatttaat tgacttggta agtcagaacc cattccttta tatccattat
     4981 ttcctagacc atatacatct ccatttgcta aaataactag agtacaataa ggactaaaaa
     5041 cgacatctct tacagaatgt atatctagtg gaagttcaat atcttttatt tccatttctt
     5101 cttttaataa agttaattta tcctcagatt taattaaatt tatataatta ctataactat
     5161 atttttcatt atccattttt ttaaattcta caacgtgcat atcatcaaaa aacgaaccca
     5221 gttgtccata agtgttatcc cctgtacaat atgaatcatt atttgaatca attagtatgc
     5281 tatgtgataa accaatgaaa atattcttag ctacaatatt ttttaaatct ataaatgaat
     5341 tatctatatt ctcagagtaa tttgctatac ccaactggta tatatcatta tttccagcaa
     5401 ccttcaaaat acctttatta tctataagca tagtattacc attaccacat gcaatagttt
     5461 ttatatttac ttcttctatc ttagtaaata gtgatgattg aagtgcattt ccaaaacatt
     5521 tttcctttcc acaaccatat atatcattat tatacgtcat taacacagtg tgttcagaac
     5581 cacaagctat agtcttaaca tcattaatag aaactaaact aaataaatcc ctattattct
     5641 tatctcctaa acctagttga ccttgattat taaaaccagt agaatagcat ttattgtcat
     5701 tctttattat aaaagctgat ttattatatg aaaatacagc ctttacattg tcaacatcta
     5761 cttttgtaaa tgtatttaca tttgcagatg ctccattagt tcctagacct aattgaccat
     5821 acaaattatt tccagcaaca tataaagttc catcattgta taaaagatat gttgattgaa
     5881 gtccacatgc aatatccttt acgcctttta tttctagaac cttctcaaat gtagaaactg
     5941 ttttccctac tttttctaat cccaatccca tttgaccatc tgtatttata cctgcgacaa
     6001 gtaattctcc atctgaagta agtataactg catgagattc tccacatgca acttttttaa
     6061 tattggtaga tatatttggt attttcgtaa ataattttct tgttgtattg tcttctccca
     6121 atccaagttg aaagttacta ttatctccac atccatacaa gatattatta ttttttagac
     6181 caaatgtata gttacaacat ccagtaaaaa aattaataaa gtcataatta tcataccctt
     6241 catcaaattc atcaactacc atatttttat cgccaaagaa attacctctt tgaagtagtt
     6301 tagttctttt cattataaaa acctcctaat tatcttattt catacgaata tttatttaaa
     6361 gttatatctg tctgaccaat tgaatatgcc ctattagatt ttgtttcaac aaagttatta
     6421 tccatttcat gtatatatct aactctattt gcattaaatg gtagcaccac attcttaaat
     6481 gtaacactac caagttctcc agttatacac tttctattta aatctaactt aaggccttct
     6541 atagctatta tgtttttagc attagttaag gtatcatacc aatatccagc ttcatctaca
     6601 tctatttctg actctaattc taagtatatt aagatatcta atactttttc agataattta
     6661 ttgtaactat tttttaatac agatagttca gtttgtattt gacctcctat tacatcatca
     6721 atagatatat ttttaatttt ttctactacc tcatttatag ctcctgataa gtttttagct
     6781 tctgtagata agagttcttc tccaattttt acttttattt cttttatatt tttatcaaac
     6841 ttatcatcta aatcttgaat atccttttga gttacaaaaa ccaacgtcgg gtctacttct
     6901 aatgtaacat ttgaagtatt ggacaattgt aaaatcattt ttacaaccaa atctttaata
     6961 ctgccatctt cagcacgtgg cttatacgtc tctggatact tacctatagc tattatatta
     7021 ttctcattat ccaaaacagc agcttctctt atcataaatc caccaactgt tcctggtaaa
     7081 atagtctcta taactatcca attaggattt ttttcatcaa ttcttagaga atttatattt
     7141 ccttcccaaa ctacattctt taaagcagtt tgttcctctg ttggctcata atattctcca
     7201 ttactatctc caacttgaaa cttggttaat ccaacaagct ctcctagtgc agttgcattt
     7261 gctatttttt ctctaccaat tttggttaat attatataaa atttttcttc caattatacc
     7321 acctccgatt taggataaac tactacattt tctacgcctg tatcatttgc aatagctata
     7381 ttaatcttac aattattttc aatgcattta atgcttaaag gataaacctt tatttcttct
     7441 ctacttaaca ttccagctcc acagtttaca acagcactac attttataat tggttcaaag
     7501 tatggatgaa cttttacctc ttcactacat accatacctc caccacaata gaccatactt
     7561 ttatctagta ttattggttc taaatagtgt aataagtgag caggttttac tctttcaatc
     7621 atatcgctac aatctaaaag agttttatag tcacagttat ttgctataaa actcaatacg
     7681 aatgtaaatt catcactata aacttttata tctgtttctg attttgtata tgcctcacat
     7741 atacttttta taacttcaat agtactagta cctctgcttc tcattttagc ttttatattg
     7801 ctacgtcttg tgtcaaaatc aagttctttt ttttcaatgc agagtatgtc ttcccacata
     7861 tctaatcccc atgtcgctgt atcaacaaat aattggtcaa aggtatcatc aatatcttct
     7921 ttaagaatat ttaattctgt atcgtatgca ccttgtatct cctctacaat gtaatttcta
     7981 tcaaatgatg gtagtttatc aattagcttc attgattttc cacctcacta aaattgacag
     8041 ttgttacact aggtatttta tcttcattaa tggttatatt atctgtactt ccatttataa
     8101 gtagattact taaatcgtgt acaccagtag tatttataag tattcccatg acttttgtat
     8161 agattatctc tcctctaata tctctaaagt atgtatttat actttctagg aaagattctt
     8221 ttacattgtc taatgtatat ccatcttcta gtttcattac tgcacttata cttatttcta
     8281 ttggtaatgg tgtcacaact gttatagttg gtccaatagg cttctcttca tctatatgtt
     8341 gctgacatct ttcaatcgtt tctgtatcaa cagcttgatt atttttccca aatatcaaga
     8401 ccttaactgt tcccggacca tcccatcttg gataaacctt aacattatag actccatcta
     8461 cttccaaagc ccattcttca tagtgagctt tatttccact tgtagcttga tttctttgga
     8521 ttttataaaa tctttctttt agttcttcat ctgtctctat atctgtacca ccttcaaaac
     8581 ttcttgtgtt agtaatcttt gttactccag atatattatc aactagttta aattcacaat
     8641 ttgtaggtaa attatatttc ttaccaactt ccagagcttg aactgggcta ttgtcacctt
     8701 cttcactacc aatagttaca tcttttatta ctacaaatag taaatctcta tatgatatta
     8761 ttgtgccatt atttattaca gttcctttct ctccaataaa ttcaacttct ccatttgact
     8821 ctgtacctaa ctttctatat acaccaaatt cattgactct tttatcaaga aattggttat
     8881 atgtgtcttg tataaaagcc attttatgta tctttgaaag ttctagatat atcttcgaaa
     8941 gttctagatt atttccagat accatgttgt ttagaaaaga accttctcct ttataaatat
     9001 caagattaat attttcaaga gttctatttt ttattacttc atatgtctgg tcactataca
     9061 tttatttcca cctccccata gatagtggat acttttacat ttgcactcaa tacgtctctg
     9121 ttaaagttag cactttttac gtttacttct aatatatatg gatttattag aagggcctct
     9181 tttatgaatc tactagcttc actttctgta agaccttttg tatatttttg tcctattagt
     9241 tctgaaagct ctgtcccata ttctaaagag tatatctcat gttcatatct atttgtcttt
     9301 atacacttgt atatccaaac ttttaaggct tctttttttt caattatttt aaagtcacct
     9361 ttttctaaaa taggttcatc tttttcaaaa tcccatgcca cttcacgaaa gattggcaat
     9421 tcttctgttt taggtaagat ataatcttct gggacaccta taaaaggaaa tattgtactc
     9481 attataagct caccaactta cttacaacag caaatttttc gcctattcta aacattatta
     9541 ccatatcccc agattcaaag ttatctataa aaggattttt tacttcatgc tggtgttctt
     9601 gatttgtttc tgtgtcaaat gtttctagct gtctatcaat catccaacta tctatcaaaa
     9661 tatcttcttt ttctaatatg atgttatttg tctctatttt taaatctggt aatttacttt
     9721 taatttttcc aataaaaaaa gaaggttgat tatgatactt tccttcttct cttattattc
     9781 ctataaattc atttattgga ttagccatta tatcaccatc cttttataat actctcctag
     9841 ctgtattaaa atctcttcta ctacttaact tacttatttt aactacatca cctttttgtg
     9901 gagcatgtaa aaattctcca ttacctatat ataatccaac atggctgact ggattatgaa
     9961 aaaatactaa atctcctgct tgaagatttt tttgttctac tttcttgcct tttttagatt
    10021 gttgatttga cgttcttggc aaactaacat taactttttt aaaacagtag accattaaac
    10081 cagaacagtc aaaactactt ggtccatttc caccccattt ataaggttta cctagatgtt
    10141 tttttgcttc tgatattact attttagctt tatcagatac attaccagaa taaccaccaa
    10201 taataatttt tccttttctt cttccaaatt tactagcttc ttcaacattt ccaaataaaa
    10261 tatctatatg gtatgttcca tttttttcta tagttattgc aggtcctaca tcatttactt
    10321 tatagactcc atcacgacca gaaactcctg taattacctg tatttcatct ccatagttca
    10381 ataaaggatg tttatttaaa aactcttttg tataataagt ttgctcatat ttaccaacca
    10441 taggagcagc gcaagttttt ttagatgggt caagtttttt ctttctacaa tctgtatctc
    10501 caccttcttc ttttctagga cagtaagctg taaattctgc tgtaaactct tttcctcctg
    10561 cataatcttc tccccctaaa ttactttctt ccttaggttc atcctgtcct gctgactttt
    10621 catccataag attttgaaaa ttaagttcaa gctcaatttg atattctcca ttttgccaag
    10681 tatgtttgtc tgtatctata taaaatagtc ctacaagctt tgtataagaa tctttaactt
    10741 ttactcctct accagttata caacttacat ctccataacc tttaagagaa cagctttttt
    10801 ctatcccatt aaactcgcta tcaatatcta catcttgatt ttcttgttgc tgaattactt
    10861 tttgcattat tacatttact tccttaaaaa tttcattatc tattttttcg ctaatcttgc
    10921 ttccatactg gtctaccact attactttat tttttacatt ttccatgctc tccgaaaagg
    10981 tggtatttat aatattaaat ccctcttcaa acataacact taatgtaaca gttccttttt
    11041 caataacatt aaacttatct aaattagcct ctatcatata ctttttcttt gtctttttac
    11101 ttgcttctgt atatgcactc attattgtgt cataaccatt tactcctata aacatctttg
    11161 tatacttgac attggtcttt gctattgttc caactgaaag cctattttca gcaaatactt
    11221 gctttgctat gtcttcaact aacttatctt taaaattgta tgacacttca ctttgtgtaa
    11281 gtaaaaatcc catatcttta gatacaaaac taatttcatt actgcttgaa tctttagacc
    11341 tattaattat cattcctcta aagagttctt tctcatctac atagaaacag actgtactag
    11401 ctattggtat atcgatttgt tggaaattta catcaaatga tgattgtatt attgaaaact
    11461 ctagtgtcct tgatggagat ttataatcac ctgaccatga taccttgtct actatgtcag
    11521 ttatgtcata tatacttccg ttttttatgt gtacccaaat cttaataata aaaaatcacc
    11581 tgccttttca tttaattcta tcagcagtta cttacaactt attatctata atagttattg
    11641 ttttggagtt acttttggta tctttattct tttatactct tttaaatcta atgtaaaata
    11701 tacatctcga gtcccatctc tttcttcata actaaaccct tcaattatga cttccatatt
    11761 tatatttgtt tccgtaattg taaatcttaa tataaaacct tccttcatcc atttttctat
    11821 cttatttaca caatcatatg gtgatggaaa acctgtatag tcacagaaag tgtagtcttt
    11881 atttggaaaa aaacttgata ttgaaatgct tttaagagct acaccaccaa aagttgctac
    11941 ttcacctatt ttgagtatac tagaagagtt tacagcagct tttccattaa tactaaagga
    12001 agatggaaat actggaaatc taaatctatc ttctgcttgt ctaagccaca tttccattat
    12061 aagacacccc ctaactgtgc caattggata cttgcaacta attttgatgt tatcttttct
    12121 atatcagctt cttctctaat cactattgta tcagctaact tagctatgtt tatatttcca
    12181 ccattttttc tgcttctata ttgatttgct tcttgtttag ttaaaaccat ttcaccttca
    12241 tggagtctgg tttgatagtc attataagga acatagttca atccaaatgc attattacct
    12301 ttcttacttg aataagcttt accagaatca ccagcctttg ttccagcata tggattatct
    12361 ttgtaatttt ttttactctt ttccactaga tttaaaactg ttcctgtgat gcttccattt
    12421 tttatcttat taatcatagt ttgccaccat ttgcatatat ctttaactat tttacatact
    12481 ttatctaata tgttaaaaaa agctcccaat attggctcta taattttcca tccagtttcc
    12541 aacagaggtc ctaaggtctc ccatacagtt ttccaaataa cacccagtgt ctctataaaa
    12601 ttgtttattt gaggtgcata ttcacctaaa aaagtaaaaa ttcttgtgat aataggacta
    12661 acagcttcaa ctacaggtcc gattagttgg aatgctgtag ttactattgt accaaatata
    12721 cttattaatc cttgtgcaat tggtgattta ttgtttatac tatctagtaa attatttact
    12781 aagtttacta ctggaagtaa tgaatctatt aatgctgtaa aatcaatatt ttgtaatagt
    12841 gtacttcctg cgttaacaat tgcttttggt gcattcccta tcattgttgc tgcatgattt
    12901 tcaaaacgtt cttgcttatt ttcaaccatc attttacgct tttcagcctc attagaaatt
    12961 cgatattgag tagaatcaga aaactctttt ccatttttta cacttctaga ttgcatctgg
    13021 tcatatttgt tgccaataat tatcttacca ttcattacat tgcctatttt accagccatt
    13081 ttttcagata agccagctaa attccctaat ccactttcta taaaagtttt tattttcttt
    13141 agtccttgac ctaaaatatc atcaaaaggt ttaacaatac tcttcaaacc attgttaatg
    13201 cttgtttgag ctcctgatat tatacctggt attgtattac tcatttcttt agctaacccc
    13261 atctgcttta cacttatgcc ttccaatgct tcatcaaaag ttttataatt ttctcctacc
    13321 agagtattaa gagattccat atttcctttt gctgcactta agaaagctgc tgatacatct
    13381 tgttcactac ttgtattcat atttaaagct ctaacatcta ccatagcttg agttatatct
    13441 ttttcttttt tgccaccagt aatattacta atcattttag ctttagttcc cattgcaaca
    13501 acatcttcag ggtcaaaagg cgtatcattt gccatattta ctaaactgtc ataatactta
    13561 tcaacatctt tttggctagt ttttccagta tttcttttca ttacactttc tagaacaact
    13621 ttctgatttt gttcctgacc aagtaagtca acaccctttt tcacagcgac acctatagta
    13681 gcaccatttg tcaaatcaga tatcttccct tttatcgaac caagtattcc acttgccata
    13741 tcctttacag ctattgcacc actccatacc ttacctgcaa acaatctcaa tttgggaaat
    13801 actttactta taatgctact tgccatatct tttatagcta ttacaccact ccaaaaagta
    13861 tttttaaaca acattaactt aggcaaaatt ctagccatag cactacttac catatcttta
    13921 agattaatac ttccttgata aggacgtttc tctactcgtt ttaattttcc caagatacta
    13981 cttatcactc tcttagtcat atcttttgct tttattacga tattccaaat cttgccacca
    14041 atctttttta aatttccaag taatttattt ttagtttttt ctacttcatc acttttagct
    14101 ttaaatatta atataatcat aatatttgaa ttaaactcat ttttcttttg aatcaactta
    14161 ttaaaataat caataatcat agctatagtt attgctagtc tcataatact tccatttaaa
    14221 cttccaataa ctcctgaaac agcatttatg ctagaactta attttgccat agttgaactt
    14281 acactactag cagtagtttg aacttttctt aacgaggaat ttaaactgtt tactctacta
    14341 cttgcacttc caatagaatt ttttatgcta ctagccatta cattagtgga aagtgaaaca
    14401 gccacagttg ctctcctaaa attatcagtt actgatataa tttggttcat ttttggtgtg
    14461 taattatctg taagatacat atttatacct tcttctctca catttcccat tacataccac
    14521 ctcctgtcaa aggacacact ccatatccat gtttcatttt ttcaacttct tcctcaattt
    14581 ctaaggcgaa aaaagcttca ataagcttta attcgccttt atccattgca taaaaaaggg
    14641 acggtcttat accttttttc ttccaataat agtacattat tgtagtcttg gtatccgtcc
    14701 ctattagttt tttacctctt ctatcactgc atttttacca taacccataa catcttgaag
    14761 tattctatat aggttggtaa tttcacctgg taataatagt tttcttgcca attcttttgg
    14821 tgttggagcc ttaaatttat ccattagttc cttattttta aataaaagct ttccatccaa
    14881 atcacaaaca ccttctataa ttgtaagcat ctgcatctcc ggtaagtcta tatccgtttt
    14941 catattttca tcaattttaa gacaagtatt ttgtatctct tcatctttgc ttattgttaa
    15001 agctctacac attactttaa attcctgccc aaatatagtt gataatctct taagttcaac
    15061 tatagtactt ggtctttcta agttttctgt atctgcattt aaaagtaaat ctactatgtt
    15121 tatatttttt gataatccat tttcattcat tattatttgc tcctttatca atcaaattca
    15181 atcaactaac ttttttactt attaactacc taaatttatt aagtatatat ctactaaata
    15241 tcagtataaa accaaatata aaactaaatt atatcaagaa aatcatactc agtaaatgtg
    15301 aaaggtgctt ctatctctcc ttttactcca acctcccaat cagctaaagt taaatcatca
    15361 aatgctatat tttttactgc tattctttct gctccataag aatctgggtc atttaatttt
    15421 gatatagcaa caaatctagg ttcagaacct ctctttatct tttctccaat taacttgtgc
    15481 attcttgaac taacatggta tagagttatt gaaccttttc ctttatatcc catatacttt
    15541 gtatcagtac ccatttgacc tgctattata atatcctctt ttgtaaattc catctttgct
    15601 tgaaacttct ttacttctgc tactttgttt ccatcaagcc aaagttctcc ccaagtacca
    15661 ctcattacat ttctagcttc catatttgcc atattaataa tcctcctata tttctattga
    15721 taaatctata tcttccatag catcaagtac ttttattttt gcttttaaaa atactttaga
    15781 acctgtgtta gcttctttta tttcttgtaa tgtcatataa gataaatcta ctccttttga
    15841 ttttaaatac gatttttgtg cttcaaaatc tatttcaaca gtagaatcag attctataag
    15901 tgctgatttc tctaattctt ctaaataact ttttatagct actatcaata aacatttgtt
    15961 gtcataactg ttagtaacct ttcctatata gtcatctatt atcacctttc ttatgtcact
    16021 atgtataata tctaaagtgt caactatttt tattttctgg aacatttctc ctttttctgc
    16081 tgttaattca gttaaagaat ttactcctct agcaattctt atagctcctg cttctttaat
    16141 aagtataagc tctcctttat taacctttga ttctgcatca actttcgtca tcttaggtat
    16201 atcgactaca tcactaagtt tagtataagt tactgattga cttaaaggtg tacctgctat
    16261 aagtccagcc accctacttg taaactcatc aacactgtat ttcttttctc caactaacac
    16321 atcttctgta gtaaaattaa ttatcccttc atgatttcct acaacttttc ctaatacagc
    16381 tttaacctta accttatcta tatctctaag tttaattatc caatttttta tagcagtctt
    16441 atcagcttct actgcttttg gcatacatag ataattaaat tccttagtct ctaaaaaatc
    16501 taatgcagtt tgaatatctg cttctccttc tattacataa actaataatt tatttggagt
    16561 gttaacattt cccatcaaag ctaaatttat atattcttta ttttcagcag ataaatcaac
    16621 tggtatatcc tctttttcat gtatttcatt aagacctagt gccttagcat ctttaagcac
    16681 cattgcaatt attcctctag ctgaacgttc tttaacagtt gtagctagct ccttaaatga
    16741 tatgttgata cttggtaatc ctatagccat actatcactc tcctaaattt aaattgattt
    16801 cttccatatt ttcatatact acatcttctt catatacact atccagataa tttagtgtaa
    16861 ttgtaaagtt caatacataa attgactctt cttttttaat actttgttct agctttgtta
    16921 tatttaattt tctgtctgtt acctttatat ttctgttgaa taacttattt aattcatctg
    16981 aaatttcata cattctaata ctctttgact gtggttttgg taagtatttt atagagataa
    17041 caatatcttt attattcgta tttaacatta taggtgtaca aataactgat agtatactta
    17101 caaaaaaaca agacccttca gagccttgca cactttcatc atcaataaaa atactttcag
    17161 taaagttttt tttgagaatc tcaataattg tttctaatat ttccttgtat ttaagcaaat
    17221 aatcaccaca ctatcactaa atattcttgc ttaatctgat aatcttacta taaatgatat
    17281 aagtcatttt taaatataca tctcatttat tcctgtcaaa tatcttctat atttttaggt
    17341 aatattattc ttttcaattt atcacctcct tcaatatgga tttctttcac aataacatta
    17401 tctcacatat tttattgcct agtgttgcaa tagtgtatat aaagtgttgt aaagttgtca
    17461 tattttttat aatatctcac tcaatttaaa tatcattttt ttctttaaat tgtagcaaga
    17521 tgttctatct aagtgtagtt tcatagaaat atatgtcata ttgttttttg tcttactatt
    17581 ataaaaaaga ttaaaaaatt ccatttctat atcatttaga catgttagag cattttctat
    17641 cttctctttt tctatttcta tattttcttt ttccattttt aattttctta atctttcctc
    17701 tctttttaac acctcatttt ccacagaaga acttatgtta tatgtgttac tagtcttttc
    17761 tgtatatacc attgctccac atccagagta ttcattctca catcttttta tgtccaaatt
    17821 aatattcttt atctttatat ccaaatactt ataattatgt aatctttcat ctgtttcttt
    17881 aaataatata tcttttttgt tttccatagt acttctcctt ttttatatac ttattattag
    17941 cttcaaattt acaataatct ctttagtgca cagtttttta ctaatctcac aactttcaag
    18001 aacatattgt tctataactg tataaaaaaa acttcttcta tattttgttc taaaatacta
    18061 gaaatcttct tagccataag aagatcagga ttttttatac ctctttctat ttgagatata
    18121 tagtcatttg taattccagc ctttctggca agttgaattt gtgtcatacc tttgcatttt
    18181 ctataatatt tcaagttatt tttaaacatt gttttatacc tccattacca ttaagaatat
    18241 tttgttcttc cacacttaga ttatatagaa tcatttgttc tttatcaata gattttagaa
    18301 aaaaatattc ttttatattt tattagtttt attttttaga acaatttgtt ataatctata
    18361 cataaggtgg tgttataatg tttgccaaaa gattaagaga acttagaaag gaatttggat
    18421 tgactcaaag agaacttgga gaaaaagtag gcgtttccca aagagtctta gggtactatg
    18481 aaacagaaaa cagatttcct gatgaacaca ttttaaacaa attggctgat gtatttaatg
    18541 tatcagttga ttaccttctt ggaagaacct tagttaagga aaatattgat acagtagctg
    18601 cacatagaaa aaatccacat gaagagttac ctgaagaagc acaagaacaa cttaatgatt
    18661 atatagaatt tttactaaat aaatataaaa aaaaataaac catatgatga gcagtctatt
    18721 tttctgctct tttaatataa tttaaaggca aacatacatt ctattttagg gggattttta
    18781 tgaataattt ggataagctt tttgaattag cttctcaaga agagataata attcattata
    18841 ccacttatat tgcaggtgat ttagaagggc tatatataaa caaacatggt attaaaatta
    18901 tatcattact cagtaattta aaacaaaact caaaaaaatt gacatccatc ttagctgaag
    18961 aacttggaca tcatttcact agccttggat actatgtatc ctcttataac gattattata
    19021 caaaaattat tatagataag tgcgaaaata aagccttaaa atgggcttgt gagttcttaa
    19081 ttactgaaga agatataata aacataatta attctggcat cacttgcgtt tatgaaatgg
    19141 cagacatact taatgtggat attactttct ttcaaaaaag attagaattt ttatcattaa
    19201 aaaaacagtc tttacaactt ggaaataata aatatttaat attaactaat ttgccgtatt
    19261 tctacatatt tgatccaatt tcataataaa aatagtagta attttaactg gcttaacagt
    19321 aaaatctata tatttatttt aacaaatttt ggtttctata aattcaatat taatatataa
    19381 taatgatatc atattattta aaattctaaa aacaaatata tgcttttgtt aagaaaggtt
    19441 gtttgatgaa tgtataaaga aaagttgttt gataattatt ttaagttctt agcactatta
    19501 ttttggccaa ttatgtggta taagtggata gtaatttcaa atggtactct tgaaaatatg
    19561 ttatttacca tatatgcaat cgtcgcaatt gttttcatca ttttatattc ggtgtttatg
    19621 ataaaatata aagacattac acaaatagat ttcttttaca ggataagtac tctacttgct
    19681 tttatattta cactttttag ctttttaata tacccaaaga gtttattttt cttgtattta
    19741 aagattattt ttactggaat atacctttat tattcaatag taaaaactct taaatttaaa
    19801 gatgacgaag gtgtagtggg tattatgagc tcacttttat taattgtaat aactttgttc
    19861 tactaaattt aattctattt gacttaatat ggctttaaat attagacatc tacattattt
    19921 tctgatatta tttaagatgg tagtcttata ttaataatga aatacactat gaaggagtta
    19981 actattatgg aaaaaaaagt tttagcaaca gttggagaaa aagagataac taatattgat
    20041 attgaaaatg cattaaaatc attagaccct tatcaagcta tgcaatttaa aactgaagaa
    20101 ggaaaaaaac acttattaaa tgatttagtg aatcaagaat tattcttctt agatgctaaa
    20161 gaagaaaaat tagatgaaga agaaatattt aaattagaaa tgaaaaagat agaagaaaat
    20221 gtattaaagc aatttgctat aaataaagtt ttatctagtg ttaatgtaac agaagatgaa
    20281 aaagtaaaat tctttgaagc taataagagc tctttctcta aaccagaaag tgcaactgct
    20341 aaacatatat tagtagatag tgatgaaaaa gctaaagaaa tacttgctca aataaaatca
    20401 gaagaaatat cttttgaaga tgcagctctt aaacattctt cttgcccatc taaagatatg
    20461 ggtggtgatt taggaacatt cggtagagga caaatggttc ctgaatttga agaagctgtg
    20521 ttctctatgg ctaaaggtga agtaagtgaa ccagttaaaa ctcaatttgg ataccatata
    20581 ataaaattag aagaccttca agaaagtaca gagtctacat ttgatgaagt taaggctgaa
    20641 gttgaaaaaa gtttattata tcaaaaacaa aatgaagttt atggaaataa gataaatgct
    20701 cttaatgcta agtacggaaa ccttgtaaaa tacaacgatt aatcataagg tcatatataa
    20761 aaaagctgtc ttttcacaat atttattaga aaagacagct ttttatatta aagtttaaat
    20821 attcagtttc atattatcat tcttttattg taaagaactc agcttaaaag tttaaataag
    20881 atttttaatt atcattagct aaatttttat atccacgtat tatctcataa cagtaaccta
    20941 ttacatctct tctttttatt atcccaataa atgtgtcttg gtcatctata acaggaatga
    21001 aattttgatt taaagatttt ataactaaat cttcaatatc tgcgttgatg gaaacaggag
    21061 aattatccat ttttctattt atatctgtca ctggaacatc ttccaatccc tttaagtcca
    21121 gatttaaatc gttttttaat gtccataaaa aatcaccttc tgttatagtt ccaacatatt
    21181 taccatcctt acttattatt ggaattgcag agtatttgtg atattccatt ttttctagtg
    21241 cttgccttat agtgtagtct tcatatatat atgctacttc actttttggt gttagaaaga
    21301 ataatatgtt cattacacta cccaccgtta ctgaaaactt ataaatatta ctcaatattt
    21361 ataatgttac ttttttgcag taactttctc ctttcttatt ttctaagtat tcttaatact
    21421 atacgctgta acaagcgttt ttcctttgct cattttaata ttattatgct ttattaatat
    21481 ttttatatgg tctatcagta tcacttattc tctttttaga aaatttacta aaaattaatt
    21541 gacttaaact tagccataat aattttactc tacactatta attttaacat atttatctca
    21601 ttattaatga ttttatttta ataattttaa tttattttgc tattaatttt atttacaaaa
    21661 actgaaaaaa ccgctaaatg attagcggct tatctctcat attactagaa cactaatata
    21721 tatgaatttt taattataat ctaactacgt tagcagcttg aggaccttta gctccatcta
    21781 ctacttcgaa ctcaacgctt tgtccttctt ctaatgtttt gtatccatct ccagttatag
    21841 ctgagaaatg tacgaaaaca tctccttcac cttctacaga tatgaatcca aatccttttt
    21901 cgttgttaaa ccatttaact acaccagttt tcattaataa atcctcctaa aaaaacacaa
    21961 atatttagct actcttttct gtaaccttat tactactcta tcatatatag ctatgtttgt
    22021 caattattat tatttttata cattaataat caattttttt actttataat tttaaatgat
    22081 tattatcttt tacactttat ttttctttat aattttttaa taatttattt ttattatatg
    22141 gaatcttatg gacttatcac tccagcctaa atcccatggc accaacattc tatcagtatt
    22201 atggcaagtt accaaaggat atcctcttga gtctaatcct gtcactgtcg aaacatgtgt
    22261 tattctgcct ttcttctcat aaccaacaaa atcccccgga cgtaaattat aagcttcttt
    22321 gtatacttct tcataggaac ctttagcaat taatgaacct cttccactat acagtgcata
    22381 atttttaaaa gcttgtgcat ttacccatgc ttttgtacct gctctctcgc tataattcca
    22441 aattgagttc tttttgaacc ttccactttc aaacattatc tgtgatgcaa agtttgcaca
    22501 atctccacct tctggattat aatccctata gtttggatta aatttcatac catgttcttc
    22561 atcagctgcg gctccacagt atttatgtgc ataatctata gccttttttt gttcatctgt
    22621 aagctgtaac tctacaccat cttgttgccc aatatagttt cttatatcct cagattttat
    22681 attttctaaa tttaaagagt ctgcaaaagg gtctgtgtac cactctttag ttatgacata
    22741 ttgattatct ataattttta catttagata atgatatgta cctattctaa aggcattttc
    22801 tttgtccttt tgattttcat atgaatactt atattcagtc gatactgaac agattatacc
    22861 atagaggtct ttttcttttt cttttatttt tttaatctta acccttgtct ttatgtcttt
    22921 aaattttaca ccttgcttac tagaccagtt ttctaaatac ttcatctttt ttacttcatt
    22981 ttcataagcc cacagaccaa attttttatc cgtctcataa agacctttta aaatgttttc
    23041 atttttctct aatattgcct tatttctgta gtcaaataag ttttcaagca atagtttata
    23101 ttggtctttt acatcatcac cttcaacatt tgcagattcc atgacttttt cttccatatt
    23161 tttcatactt aaatcattga ttaaaaatac acctgctgta gtagctaaag acaaaaatac
    23221 aaatgccatt atacctttga tgtacttatt cttatttttc agtattttca aagctacacc
    23281 tcccaaatag tacaccttat aaatgaaatt acaaagaaga ttctgtcata tacaataatt
    23341 ttcatattta ataattctct attttattat gtccaatatt aaaaattaat tgtatcaata
    23401 cactgttttt tttacaattt tttattttat aatctacttt tttctttttt ttatagtaat
    23461 atatatgtat ataaatattt tggtatcatt ataattaata catactaatg gagggttttt
    23521 tatgcaaaaa aaagtcgcag caattaatga cttatctgga ataggaaaat gctcattatc
    23581 ggttgctata cctatacttt cagcattaaa ggttcaatgt tgtccatttc caacggccat
    23641 actttcaagt caaactggtt atcctgaatt tactttctta gactttactg atgaaatggt
    23701 aaaatattca aatgtttgga aaaatttaaa agtcaatttt gatagtatat atagtggttt
    23761 tttgggttca aagcatcaaa ttgagatagt ggctaatttt ataaatgatt atcccaatgc
    23821 ttttatcgta gttgaccctg tgatgggtga taatggagtt atgtatccaa tattcacaga
    23881 agaaatgaga caggaaatta aagaattagt taaacattca gatttaacta ctcctaattt
    23941 aacagaagct tgtttcttaa ctggaaatga ttatactaaa agtgattata atagagatga
    24001 gcttatatat attgcaaaat ctgtatctga tttgggacct agcaaagtcg ttattactgg
    24061 tatattagaa gatgataata tattaaattt ggcttatgat agagataatg accatgtatt
    24121 ctttacatca gtcaaataca ataattgttc ttacagtgga actggagata tattcacatc
    24181 tatactttgt ggtatgttag taaataaaca tgatttggga gtagcagtta atactgcaac
    24241 agattttata tataaaacta taaattacac atctcaattt gatactgata gaaatgatgg
    24301 agttatgttt gaaaactttt tatcagattt aactaatata taaaatcaaa aaaactatcc
    24361 attttataaa tacctataaa tcataaaatt taggtattta caaaatggat attatttact
    24421 aaactattgg tatttcaatt gttaccatag caccaccagt tttcacagaa ttttcaatat
    24481 ataaaattcc attatgtttt tgtacaatat tatttacaat ataaagtccc attccgtaat
    24541 gagatttaga atttctactc aaatctcctg tataaaactg ttctgtagct tttgacaaat
    24601 ctgctttaga aaaaccactt ccacaatctg taactacaaa ttttaagtat ttattactta
    24661 ctgatacact tatgtatagt ttactctggc ttggtgaata atctatagca tttgaaatta
    24721 tattcataat agctctgaat aacagttctc tatctatagt tatattttta ggcaaattat
    24781 cttgtttata aaactccaca tctaagtttt tagtactagc taatgcttct atttgcagta
    24841 agacatcttt tataaactca ctcatattaa ttgcttcttt atttaatata tagccattct
    24901 ctgtttttga tatatctatt aaagtattaa tatatttttc tatttgagtg acaccctttg
    24961 agatatattc catgtattct aataactcag gattttcatt tatttcaatt aataagtcag
    25021 tatttccatg tataattgtt aatggtgttt ttatatcatg tgccagtgca gatatctgtt
    25081 cctttctatt ttcttctagc atccattgtt tttctaaaga attctttaac gccaacttca
    25141 ttttatccat agaaaaaagg atattgttaa tttcataaat tttactagat tctacaacaa
    25201 aatctaaatc ctgttgttct attttttctg tagtattttt taaaagctcc atttcaatat
    25261 taaatttctt gccaaatact tttgataata taacaatttc aataaaaaat attatactaa
    25321 aaataatcat acccaacatc tctggttttg gtaaatatgc tcttaaaact ggagaactat
    25381 actctgatac tagtttgtat tttattataa aaacttcatc tttcttaaaa aactttatat
    25441 aactttctga atatgcatgc ctttcttcaa tatctctcat taaattccat acttgttttg
    25501 attctttttt attaaaagtg cctgagatca aattcccatc taaagtataa acaccatact
    25561 cgtataaatt tggaattata tcttcaattg ctttttcact tgaaataatc ttttctttat
    25621 atttatcaaa ttgtttttct gaataattag ctggtaatat tacacctgat gataataata
    25681 cagaaaatga taacattaaa agaagtgcaa atgaaattgt cataacaaag aataaagata
    25741 aatattttat aaaaatagtt cttaactttt caactttttt gttgttagat tttttacttc
    25801 taagcatttg tgccatatcc tccaaatatt ttaattaatt cataattaat acctaaccag
    25861 tttttatttg attattttat atttttcatt gctaagttat attttaacat aataatataa
    25921 ataaacagtc aatttttact ctattcttct gattttttac cttcccatct agaaaaccaa
    25981 atacataaaa ttacaaatgc taaaattgtt acaaaaccac acattaaacc tgttgattga
    26041 tatgctttta ttgattcaac ctttatatat tcaaccgttt tagaacttga aaaagacgac
    26101 caaatagtta taaatctaac accccatgca caaggaaaat actgccaaat gccagaaccc
    26161 aatccagtta ataataatgc tgaaagtaac atttcaacta tacctactcc aattgatgct
    26221 ccttttccga accttaaact taagaataaa tgtaatatgt attcaaataa attacaccca
    26281 attaaaatta gaattgaaat catataaaag cttgatgcaa agtaagcctt agatatacca
    26341 aatttaaaac ctaatacaga aactaaggtt gctacaaaac caagacatac taggattata
    26401 tatttgctta taagagtaag atattttgga ttagatgttg ttaacatatg cttataattc
    26461 cctgcataat attcttgttc aacaaacatt gaacacacaa cacctgacaa taaaggaaaa
    26521 gctattgcta taacttgtaa atatgctact atctttaata tattatcagc tcctgaaacc
    26581 ttataatacc ataaaaacaa tcccatcccc attaaagcaa tgcaaatgtg cattagtatt
    26641 ataaaatttc tctttaattt tattaaatca gaacaaaata ttcttattag ttgtctcata
    26701 ttacttcacc tctctattat tgaaccaagc tcttgtaact aaagcaaata atacaaataa
    26761 aataacagat attaatactc ctggtaaaat aacagcatta tttaaaagtt cactcccctc
    26821 tggtacagga agcccatttg gtagaatatg caatacaaca accattaatc ttgaaggaat
    26881 cgaatatgga aatacatacc acatttctgt agttgagaaa acagcaactc caacaatagt
    26941 aaagaacata tttgttagaa ctgtaacaaa tataccaaat tttgaagcta aaaacataca
    27001 aagaggaatc tgccacataa atagtaaaat aattaatata gttgcaatga tattttgacc
    27061 tattgaaata gtttctttat agattatccc aacaaaaact acacctattg cagaaataat
    27121 cgatgctata aaacaacaaa taatacagta aatcattttt ccagcccaaa cgtctttcat
    27181 ttcaattggc aatggtaaaa taccacgata tttacttttt tcatctttta atactattaa
    27241 agaagatatt aatgttaatg ctcctggaag aaatgtcgta taccaccagt tgaaagcagc
    27301 attttgccct ccacctagtc cacacaaaag tatacaaaac actggaacta tccatatcaa
    27361 cttcattcca aaagttcctt tcatcttttg aaattccact ctaataaatc tttccatatt
    27421 actcccctct ctttctattt tcagctacaa ctttcataaa aagttcttct aagttttgtt
    27481 cttttgatac ttctccttga taacccatta ctccattaga aattattccg atttcatcta
    27541 caacttgttc aacttcagac aagatatggc ttgataaaat aactgtaatt ccttgttttg
    27601 gaaaagaacg aatcaatttt ctaagttctt caataccaat agggtcaaga ccatttgtag
    27661 gctcgtctaa gattaaaagt tttgggtgat ttaataatgc aatagcaata ccaagacgtt
    27721 gcttcatacc tagagagaat tgacctgaac gctttttaaa agtatctctt aagtcgacag
    27781 tctctaaaac ttcttcaatt cgagagtcag gaagaccaag taaagtagta tggactttta
    27841 aattttctcg tgctgttaaa ttctcatata tagcaggaga ctcaataaga gaaccaatat
    27901 ttgataaatc ctttctagtc catctatgtc cctcaaacat tatttttcct gaagttggat
    27961 ttaaaatccc agttatcatt tttaataaag tagatttccc agctccattt ggtcctaata
    28021 atccatatat agaattagat ttaattgcta gtgaaatatt atcaactgcc atctgctcct
    28081 taaatttttt agaaactcct tttacctgca aaatataatt attcataatt ttcatccttt
    28141 cttttgtcaa acttatttac aagaatcatt ctaaatcata aatataagga ttttataaga
    28201 attaaaaaac aaaaaaaaga tgtgttaaaa acacatcttt ttttatctta attctattaa
    28261 ttttccattg tagtatatct ctacttcttc aatccaaatg ctattatctt cttcttggat
    28321 gacattttta ataatattat ttatagtata tattatattt tgttcattca aataatcatc
    28381 tttccaagaa actctacttt ttttatctgg ttctatcaag tttattttaa caagattatc
    28441 tttttcctta acttctactt ccatgtctaa accattaaaa tactcatttg ataatgtatc
    28501 taagattaat cgcagtttat ccttaagtga actttcttca tcaatctgta agtactttac
    28561 tattttctca tcctttgaaa ttatctctat aggtatttta gtagtttttt tagaattaat
    28621 cattttacta gttgtttctt cttttgcatc ttcatccttc tttacaactg ctgattcttt
    28681 agaatcaact agctcaactg cactgatgct ataatccata catgctgtac tcaataaagt
    28741 agtagcaatt attaaaaaac ttactgctat tttattcata agtatccctc tcctaattct
    28801 ctttcgatac ttattatacc atagtataga ttatattttt atacttttaa atcaatttat
    28861 aaattattat agtaaattat ttacaattct aagctatttg aatttatttt tatagtatat
    28921 tctttctcta aattcgacag atttttattc aaaagccctt ttatttccct cgtatttcta
    28981 tacttgttgc tatgttcttc actatgttca taatcatatg aatcattgtc atattcttca
    29041 tcattattaa attcttcgat tacttctttt gactttatat cacaattaaa tttatactta
    29101 tttactggta tatcaagtct taccttagaa tttggaactt ctatgtccag gaacttagca
    29161 attggcatat tagagtacaa gtaaaattca ctttcataat ttgaatttct acctattttc
    29221 tcttttatat ttacattttc aggtatatac tcttctatat tattgataaa tacatcttca
    29281 ttctctgaag atatatccaa tgactctgat tctatgttta catttttaac gcctaaaatt
    29341 gattttgttg acaagtgaag attgctatta gatattaagt ttaggttttc taatctattt
    29401 actttgttct ctgttatagc tctactaaaa cctccataag aagttttata tgttatagta
    29461 tttgaagcta cattatcgta tacaaataag tatgaactta tacttgatgc atttatgtct
    29521 acattatttg gtacatatat tataatttct ctataatcat gtgaaaacat actatttata
    29581 gatgtattta ataattggtc gaaattttta atctttttaa ttttattttc atattttctt
    29641 tcacctttta caactaaagt cttatctttt aaagttacat tgtatttgta aaactcatta
    29701 tttcctcttg ttgttacacg cacatcttca cttgaacttt tctttattgt aacgtttata
    29761 ttgtcaacag ctatatctaa cttgtcaata tttacttttt cttgataaag tttattttct
    29821 tttttaaatt cagcttcctt ttctaaacca aagtttatta ggcttggcat aactaaaatc
    29881 cctgaccatg ttgtccctat tatacctatt accaataaaa ctgcagcaaa tatagcaagt
    29941 tttttattca tgtttatctt ctcctttctt attttctata tcttcaaggt ccttatatat
    30001 cgcctcaaaa tttatactat catcattata ttcatcagtt tcttttatgc tttcttcttc
    30061 tctattgtag taatcattat tatatgaatc ttcattaatg tctttattca aatcttcatc
    30121 atttaaagta gctttttttc ttttttccat cttttcattt gcctttatat aaatattttt
    30181 tctctttatc caatgtatat aattatttag taattgttta cctagtttta tggcaaataa
    30241 taaaatttgc catgcaagta tctcaagccc tacaaatgct atggttgcga aaatacaaaa
    30301 catcataaca tctggaacca ttgctataaa tttaatcaca aatggaatta atataacaaa
    30361 agcaattaat gaacatacta atgcaatagt aacagataca atagcacata caaacgcaaa
    30421 tgctggaaca attagaaata aagataacac tactaataat ccctttataa cttgtctaga
    30481 taatccccct acaccttctt ctatacttgg tgtaagttta tcatttatat tttcttttga
    30541 tttattgtac ttttccttag cttcatcttt caagatagag taatcctttt ttatatttga
    30601 tttaaaccta ctaaatttac catttaatat atctgtattc attatttttt catctatatt
    30661 ttcttttgat ttactatact tttcttttgc ttcatctttt aagatagagt aacctttttt
    30721 catatctgat ttaaatttac taaacttatc attcaaaaca tctgtattta ttattttttc
    30781 ctcttcaata tttttttctt tagtctgcaa gataagttct ttggctatag attttggtga
    30841 accaagtgat gctattatct ccatatcact ctttccctct ataagaccat ctacgaaata
    30901 ctcttcataa tctctcaata tatcattaac ttcgctctca gaaaaatctt tttttagata
    30961 atcctttaaa atttcaagaa actcagtttt attcaagttc attacctccc tcatcttcac
    31021 ttattaaaat ctcaacagcc tttacaaatt ctctccactc ttccatcaga ttggataaat
    31081 tctcttttcc tagtgaagtt attctatagt attttctagc aggaccttca ttagattcta
    31141 gtatatatgt ttcgaaatac aaatcttttg taagtcttct tagaatagga tatattgttc
    31201 cttcatttac atctattact ttagagatgt tatgtactat ctcatatcca tacatatctt
    31261 tcttagatat gagagcaagt acacaaattt ctaaaacacc ctttctaaat tgtgtgttca
    31321 tatactccat cctttcttta aatacacagt attgtgtttt acaaggtact atgttaaaac
    31381 ttcttatatc ctcataataa cacagtacta tgttctgcac aatagttatt tttaaatatt
    31441 cttgttgatt aaatccttct ataaatgtat aatactctaa tcagatatat tttatgaaag
    31501 tggtgataaa ttggctaaaa tgaaagatga taaaacaata ttaatcttaa ctgctcaatt
    31561 tggtgctgga catataagtg ctgcaaaagc agtcaaagaa tgtattattg aaaaatatag
    31621 taactataat gttgttatac aaaactttat aaatgcaagt attcccatga tgaataaacc
    31681 tatggtaaaa ctttatgaaa acaatacaaa atatactcct ggattatata attactatta
    31741 ttactttaag aaatcgtttg attcaagaca tgatttatct cataaattat atacacctaa
    31801 actttctgag tatattgctg atataaatcc agatttgatt atctctacat ttccactagc
    31861 ggctgcttgt gtaaataact ttaagataaa aaatcctgat ataaatatac ctacacttac
    31921 agttataaca gatgttgtag atagtatgga atgggttttt gaaaatacag atttgtattt
    31981 tgttccttct cctgaaataa aaaatagatt ttttcagaaa ggaataaatc cagactccat
    32041 aaaggttact ggagttcctg ttgataagag atttcaaatt gaaagtaaag aactatgttg
    32101 tgataaatat agactattac ttctaggtgg aggaagaggc ctatttgata tagatgagga
    32161 ttttatgcat tggatagatg aatttattga agaacatagt aattctatag aaattacaat
    32221 agttactggt aaaaacaaaa aattatatga caatctaact cataaaaaac ctctaaaaaa
    32281 tattaaagta cttggatttg taaacgacat gtataatcta ataagagaat gtgacctaat
    32341 gctaactaag cctggaggag caactatatt tgaagctatt caatcacaaa ctccagtact
    32401 cgtgaaaatg ccaaaagttg gacaagaaat tgaaaacgct aaatttataa tagataaggg
    32461 tcttggcatg atttatagtg atgacctaga ccttaaaaac atattttata aattagtatc
    32521 aaatgaattt gattctataa taaactttat gaaaaaaaat ttagaagaat ttaaaacagt
    32581 tattcatcca gagaaaattg ctgattatat atcagaatta atagataatc attacagtta
    32641 aattgtacta ttaaaaaatt tcaaacataa aattaaaggc aatcaagtat gcttttacac
    32701 ttgaaaattt actcatagtg tttaataata cttgattgcc tttatcatat caaaatcaaa
    32761 ttgttatatt agtatatatt tttcttgtac tgcatataca gttgttgtat ttcttccata
    32821 cttctcttta attctatttg taaatctgaa gcagtctggt aatccttatt ttctatagct
    32881 tctctcactc tagtgaatag tgattctcta gttaaagtat ccttcataat attgaacttt
    32941 aaatccgata ttgagttcca aactacctca tcaagcgcat ccatattttc ttttgtgtgt
    33001 atcttgacaa tacttcttat tttttgaatc ccagcctcta ttattctagt ttttaatttc
    33061 ttttgccact tatctatagc tccaatctta aatgattcta ttatactatc agtaaataca
    33121 tcaccttgtt ttaaagattt taattttgaa gcatatattt ctaagttttt catattttca
    33181 taaactgtag ccggtggtat tccaaatctt gcatttcttt cttccaaact ataatgttca
    33241 aatacatcat tttcatctct atatgctcta tctttttcta aatagaaact ttcttcacct
    33301 acatttttag ataactcttt ttcaagttct tttgtactaa gaccactctt agctgctgct
    33361 tttataccat ccaacattgt ttgataacat cctgctatta ctaaatatgt gttagataga
    33421 gggcttggtg accttaactc aaatcttaca gtctttggat ttttcatatc tcttattaat
    33481 ccaacaagca ctgacctatt tcttgatgga atctcataac tatgccctaa agatgtaact
    33541 atgcatacag gagcttcaaa tccaggaact aatctattaa atccatcatt agaagctgtt
    33601 acaattgggt ttaatacttc ataattgtaa agaagtccca taagagcccc atatcctagt
    33661 tcacttagat aatcttcttt taaatctttt ggagcaaata gattttttat acttccatcc
    33721 tttaacttcg cacttactcc tacatgtgta tgtccaccac ttcctgctac tccatgaatt
    33781 ggctttgctt taaatgtaac ttctagtcca tgtgatgtaa atacatcctc tataacatct
    33841 cttactaata attcattgtc tgctgcttgt aatggtgtag aaaacttcca agaaacctct
    33901 aattgctcca tagcatggtt tgttcttcca tctatactaa tagaactttg tattcctccg
    33961 acctctttgt gagccatttc aggatttaca cctagctttt gaagtataat taaacttttc
    34021 tctaaacaag ttcttataat accatgagtt cttttccagt attgctcttt taggctttgt
    34081 gatacatata atttctctaa gtcagcttta tcctcaggag tattaaccca gaactcaagt
    34141 tctgtagctg ctgttaacat tatttcctct atatcatcta ctgaatctat tcctatgtta
    34201 tttattacat gtggatattc tctaaatatt tcatacattg actttttaaa gtacttatct
    34261 gctttttgaa gtactcctct agaacatact tttttattat catgtattaa aaatgcaggt
    34321 atctttaatg ttccaacagg tagacctact tcttcgtcta tatattccat attgtaatct
    34381 acataccaat gacaactttt atctggcatt aaatctactt tcgcattatt taatgtagct
    34441 atattataaa gctcaacact tgaaccatca gtctgtatag ctgattccaa aaatttatct
    34501 atatcctcca aaaataattc tacaggaatc ttttcatctg ttgcatttcc tcctaaatca
    34561 acccccatta aggaaacaaa tcttatattt ttattgcttt ttaggatttc tcttaattcc
    34621 tcattagtgt gtttatcttt ctctattacg tataatagac tatccatttt tccactctcc
    34681 cataattttt atgtatattt tattttgtta aatacaagat aaatttcatt ttccttacat
    34741 tcatgaattt ttcttgcaaa ttattcgtgt tttattcgtg tttttattta tattattata
    34801 tatcaagtat aaaaagttcg caatattttt tattggaaaa aatattatac atacaatagt
    34861 ttaacatttt tacaaatatg gggtatacta aaataaaagt atttttattt gaaaatttaa
    34921 ttttatttat aatataatct atagtaaaag aaataataaa aaaatttagg agataaactt
    34981 tatggaatac ataattttcg atttggaatt taaccaagga tttgataaaa aactcaataa
    35041 aactgtatcc aatgaaaagt gtccttttga aattatacaa ataggagcaa ttaaattgga
    35101 ttctaaattc aatataatag atacgtttaa tagctatgta aaacctacaa tttataaaga
    35161 catacatccc tttattagtc gtatgactaa tattaaaaat tctgatttta atgattcgcc
    35221 tactttccct gaggtctaca acaattttat aaaatttata tcatcacaag accctatatt
    35281 atgtgtttgg ggagttggag atttaaagga attatacagg aatatcaact atcacaagct
    35341 accatcaagt tccttaccta aatcttatat taatatacaa caacatgcat ctaaatattt
    35401 caataatcca gcaggaaaaa gcattggcct acaaaatgct atttctatat tggaacttga
    35461 tgaaaaaatg tcttatcaca atgctttaaa tgatgcatat tatactgcta aagtttttat
    35521 taagatatac aatccaagta tagtcccaga tatatatctt tatacgagta taaaacctaa
    35581 aactataaga tattctaata aaaaaagagt tgattatgat aagttatttg atgaatttag
    35641 gaaaatttta aatcgtgaat taactaaaga cgagaaaaaa atcattaact tagcttataa
    35701 tatggggaaa acaaatcaat ttacattaga aaatgttaag caaagaaaaa acaaatagag
    35761 tttatttaga taaaaaatag gcatgtagat taaaaaacta gttaacttta aatttatatc
    35821 tacagcccaa tttttatcgt aattaatttt tattttatct ctaattcaac tggacaatgg
    35881 tctgaaccta atatttcagt gtgtatatcc gcacttacta atctatcttc taattttttg
    35941 gatgcacaaa aataatctat tctccaccct gcattatttt ttcttgcatt aaatctatat
    36001 gaccaccaac tataaacgcc ttctttatca ggattaaaat atctatatgt gtctataaac
    36061 ccactgtcta ataatttaga aaacttctct ctttcttctt tagtaaaacc tgcatttttc
    36121 atattatttt taggattttt taaatctatt tctttatgtg caacgttcat atctccacac
    36181 acaattacag gcttatgatt atctagtttg gttaaataat ctataaagtc gtcttcccat
    36241 ctagttctat attctagtct ctttaattca gattgagaat ttggcgtata tactgtaaca
    36301 aagtaaaaat cttcaaactc tagagttatc actctaccct ctttgtcatg ttcttctata
    36361 tttattccat acattacttt taaaggctct ttttttgtaa atatagcagt acctgaataa
    36421 ccctttctct cagcataatt ccaatattga aaatatcctg gtaaatctaa ctctatttgc
    36481 ccttcttgca atttagtttc ttgtaaacaa aatatatctg catctacttc tttgaaaaag
    36541 tctaaaaatc ctttcccaac acaagctctt attccattaa cattccatga tataaatttc
    36601 atacttatac tcctcatcta aacattgaca cactccccat agctaaagat gggggctttt
    36661 caacaatttt attgtaaatt cttaatttac ttttatttta acaatactat actataattt
    36721 catctaaaat tactatttac ttaataccta aaaatatatg ttttaatcaa tttttaactt
    36781 ttttgttaaa tcttcagggc tcattgaaga aacatacata tttgttccaa gttcaaatcc
    36841 tccaaaatta tattttcttg ggattatgtg catatgaaca ttaaaatacg attttgtttc
    36901 aatctttgtt ggatgagtgt gaatacataa gttaaatggc atatatccat tgatattgta
    36961 taacttctta aacaactttt caaatattgt agaaagctcc tgtatattat tatcatttaa
    37021 ctcaccaaac tctattttat ctttaaatat tattcttact tctccactat acttggttgc
    37081 atatggtata agtaccaaaa aagcttctcc attataaaca actcttctat ctaaacttat
    37141 ttcattttct attaaatcat catacaaaga gcttttattg ctgtcataat actcctttga
    37201 aactagcagt tcattcgtaa tttcaggtgg aataaaagac atagacaata tttgagcatg
    37261 tggatgcatc aaagatgctc ctgcctttct caagaagttt ttgaagatac taacatactc
    37321 tactttatca tctttcgaca aatctctaaa tctatttcta tacataaaaa aaacatcttc
    37381 aaattctttt tgactcatgt tataaaaact acgattatgt ttatcgctct ctatcattac
    37441 ttcatgaaca ccatatacat ctcttgccat atcatcaatt ataggaaatt tattgtagac
    37501 agattttaca agccatcctt cttcactttc tatttcaaat aatgcatcag ttgcatgagc
    37561 ttcatttcct ttgcaaaatg ggcattcttc atcatattca ttagtttctt catcttcatt
    37621 tgggatatct gctgtatcta aaggtctttt taacctatct gtagcaaata taacaacatc
    37681 attagtaatt ggatctattc ttaattcttt cataattaac acctcttagt taatagcctt
    37741 taatataatt atatgatatt tatcgtatct gttaaataaa tttataatat tttttataat
    37801 tttgcatatt tattattata tattttgtct atagctgaaa gattataact aaaaaatcac
    37861 tatcagtgta tcagaatatt atcttactat aaattaattt atgaatacat aatttagtgg
    37921 cataaacatg ggtattttac tataatttgt taaaagttta ttttaaagct atattaattt
    37981 tttttgatga tttttaccca taagtatgtt attattatct tgtaaagatg tcttgtattc
    38041 aaacatacaa tttacataat acaatatacg tatttaaatt aaataggggg tattaaaatg
    38101 aattattcaa acagagttag tgcaatgcaa gcctctccaa tcagaaaact tgttccattt
    38161 gcacaagcag caaaagataa aggaatcaaa gtatatcact taaacatagg acaaccagac
    38221 ataaaaactc ctaaaggatt ttttgatgct gttaaaaact ttgatagcga agtcttagaa
    38281 tatgctacat cagaaggtat tccagaatta ttagaagcac ttcaaaatta ctataaaact
    38341 tacgatatga attttgaaaa agatgaatta ttagtaacta atggtggtag tgaagcttta
    38401 cttttcacta tgatggcagt ttgtgaccca ggagataatc tattagttcc agaaccattc
    38461 tatacaaact acaatggatt tggtcaatct gtaaatgtag aagttaatgc tgttacaaca
    38521 aaggcagaaa acggtttcca ccttccatct aaagaagaaa tattgtctaa agtagatgat
    38581 aaaactaagg ctataattct ttctaaccca ggaaatccaa ctggtgcaat ttatacaaaa
    38641 gaagaactta atatcctagc tgaaatagct aaagaaaaag atttatggat aatagcagac
    38701 gaagtttata gagaatttgt ttatgatggg cttgagtata caagctgtgg taacttagag
    38761 ggtgtacagg atagagttat aataatagac agtgtttcta agagatacag tgcttgtggt
    38821 gctagaattg gttctattgc ttgcaaaaat aaaggtctta tagctcaaat acttaaatta
    38881 tgtcaaggaa gactttgtgt tcctacatta gagcaaatag gagctgttga attatataaa
    38941 actcctgttt cttacttcaa agaagttaat gaagagtaca aaaaaagaag agatgtatta
    39001 tacaatgaat taatgaaggt tgaaggtgtt atatgtaaaa aaccaactgg tgctttctat
    39061 atagttgcta aattaccagt tgaaaatgca gaagatttca caatttggat gttaaaagaa
    39121 tttaacaaag ataatgaaac agttatggtt tgccctgctg aaggattcta tgctactcca
    39181 ggtttaggac gtgatgaaat aagattagct tacatcttaa atgaaaaaga ccttcataga
    39241 gctgctacat tattaaaaga aggtttagag caatatgtag ctttacaaaa ataatttttt
    39301 aaacttaatt tatataaatt taatgatata aaatgtcccc ttttcagata ttatttgaaa
    39361 aggggacatt tcttaattaa tatattaatt aaaacttaga cctgactatt tttcattttc
    39421 tttatatagt gttggccagt aatctttatt cactttaatt aaagcatcta aaacttgtct
    39481 tgccttagtt ggagagatta tagttctatt taatgttaaa gataaaatag ctttttcata
    39541 agattgttca aagtatgcat caactgctaa cttttcataa gctagttgac cttctaacag
    39601 tcccttataa aatgttggta tattacctac atgtaaaggt ctcggtccat tctttgtaag
    39661 aatcgcagct acttctacca ttgcatcatc aggtaagttg ttaatagccc cattattttc
    39721 tgttataact atggctattt ggtgtttgtt atgagctatt gcttctgcaa cttcaattat
    39781 aaattcccca tgagcatcat tatgcactaa attagaacct atagatgttc ctttttctat
    39841 aacagattta cattcttcaa atacacgctt ttctcttcca ttcataactt ctcttgctct
    39901 agtacaattt atatttgatt tagctacttt tttatcagga tatagataat actgtacata
    39961 tgtattaggt aagtaatctg gtacatcttc caacatatct ttaaccattc cataagtgtc
    40021 taaccaagat ttatctcttt gttctgcatc aacaggttgg aatccagagt ttgctactaa
    40081 atcttttatc ttaggtacca aatcttcacc atttttatca tacaaatgtg taaaccatcc
    40141 aaagtgattt aatccaaagt atacaggctc aaatgttctt gaatccatgt ctaacaatct
    40201 tccataagac cttaacaagt taactggttg gtcacacata ttaagtaatc ttttatcatc
    40261 tggaaatact ctttttaatg cttctgcaac aatagcagca ggatttgtat aatttaatat
    40321 ccatgcttta ggagagtatt ttcttacagt cttaaccatt tctatcatat cacctataga
    40381 ccttaaccca taagcaaatc caccagctcc acaagtttct tgaccaacca gtccaaattg
    40441 tagaggaatc ttttcatcta attctcgcat cttaagacca ccagttctca tttgaacaaa
    40501 tacaaaatct acatctataa atgcttcatc tgggtttgta gtatattcaa gtgttgcttt
    40561 aggatattct tctttaaata atatttttcc aaattcccct attaatcttt gacgttcttc
    40621 tactacatct aacatagtta ctttatttag aggaaatcta tcactcattt tacataaaga
    40681 ctttaaaagt cctggagtcc aagtactgcc tcctccaact atagctatat tgtatctttt
    40741 tttcattgtc atattaatca cccctgtttt ttattaacta acttgtaaga tgattataat
    40801 atataaagtt ttctacatga atacttttag gtaatcatta aaaatagttc aattttagta
    40861 tttttttcaa aattgtaatt tttttcatct attgtatttt tcaatgtatt tatgaaacat
    40921 atattccata agagaaagtg ctggcactct agacgtatag ttaacactat taaaattata
    40981 ttgtggagaa gatacaaata attttatatc agctatattt gataatgaat tgacacttat
    41041 atttgtcaga gaaattactt taacttgatt tgtttttgct atattacatg ccttaataac
    41101 ttgagcagtc tctccagaca tagatacagc aattacaagg tcatctttag taatatttga
    41161 tgcagccaaa tacatgagag ttgaatcatc atagtatttt acatttacac ctatagctga
    41221 aaaacgttga gacatttcag tacatactaa tctagaagac ccaacaccaa aaaaatatat
    41281 atgcttagaa ttatgtattt catttaaaca catatctata ttctctacat ttattaaatt
    41341 ttgtgtatcc ataacatcag taaaaatatc actttgactt ttagtaaact ccttatttct
    41401 ttcatttcta tttgaatatg aaaaaactaa aaagttttta aattcactat atccagaaaa
    41461 gccgagcttc tgacaaaacc ttactatgta tgcagtcgaa ttaaaagttt catttgctat
    41521 atctttaatc tttttttgat ttattttttc agaatttttt agaaaatagt ttaaaagaga
    41581 tatttcattt gtagataatt ttttttgatt tatatctaat ttgtctatta ggttcattta
    41641 tacctccata ataatgattt gtagttaaac aactttctca tatttattat ataaatatac
    41701 actatacaac atttatctta tgtttattat actacaaaaa agacaataca aattataaat
    41761 tagtattgcc ttttaatatt tacattagat agacattaaa tagacattgc aaaagaaact
    41821 tcgtctctta cttgagatac agatggccca taaattattt ggatatcttt atcagatact
    41881 tttataacgc ccattgcacc tgtatatttt ttaaaagcac tttcatctac tttactcata
    41941 tctttaacta ctactcttaa gcgagttata cagtttgtta tatcttctat attctcctta
    42001 ccacctaaat atttaattat ggataatgct ctcttagtag tttctccact ttgagctatt
    42061 tctactttat ttgataaagg ttctaaatca aaatttatat ctgttatttc ttctcgtcct
    42121 ggagtttgta agttaaatct aagtatcaaa accttaaata cattataata aaccagtgca
    42181 tacactaaac caagtattat agaataaatc cactttgtat ttggttgcat aactccaaat
    42241 actactaaat ctattatgcc accttgagta tttcctattg ctactccaaa tatatgcatc
    42301 atcataaatg atatacctga taaaaatgca tgtataacaa ataatattgg tgatacaaat
    42361 aagaatgaaa attccaatgg ttccgtaatt cctgttacaa atgttgctaa agcaccagct
    42421 agtaatatac ctttaacctt cgacctattt tcaggctttg cagttttata catggcatat
    42481 gctgcagcag gaagaccaaa taccattata ggtattttcc cttgagctaa aaatctagtt
    42541 gcttctgttg aaaaactgat tgtttcaggg tcacttagtt gagctaaaaa tatgttcaat
    42601 gctccaaata cttcttgtcc tcctacaact aaagaacctc ctacttcagt aaatctaaac
    42661 atagcattta atatatgatg taatccaaat ggtattaaaa gcctttcaag aaatccaaat
    42721 acaaatgttc ctaaatatcc taaactagct ataccaatac ctacactctg aataattgta
    42781 tttacatatg gccatatata tggtattatt atccccaaaa tagagaatac tactgttgtt
    42841 attattggaa caaacctagt tccaccaaag aaccctaaat aatctggcag ttttatatta
    42901 tagtatttat tatgtaatga tgctgttatt ataccaacta caattccacc aaatactcct
    42961 aactctaatg tttgtatgcc taaagttaca gcttgaccca tttctctcat catgtcaggt
    43021 tcagcaagaa tacctctaca ccctaacata taatttacac tagtgtgtaa tactaaataa
    43081 ccaacaaaac cagaaaatgc agaaactgct ttttcttctt tagcaagacc aacagatatt
    43141 gatatagcaa agaatattgc taagtttcca aaaagtactc ctgttatagc ttttgtaaaa
    43201 cccaatattc cttgaataaa attattttct aaaaaaggta tatcactaac tatattagga
    43261 tttgaaaatg ctgaacttat tcctaaaaat atacctgcag cagatattaa tgctattggc
    43321 aataaaaatg attttcctaa ctgtaaaaaa aactctttca ttttttgttt catttctatc
    43381 cctccatttt taaattttta aaacgttttc tatgtcataa ttatatattt ttattttgtt
    43441 tttgaaactt tataatttgt tttaaaatat ttttacataa atagtaattt tttcaaaact
    43501 gtaaattttt tcaaacaaag acatagtaac attgtgatat atagaaattt aaaaagagat
    43561 tagaaaataa aattattgaa tataaaatgg aaaaatataa attacacaaa gaggtatgag
    43621 taggtactaa caaataagaa aatgtataag aaattataaa aaagtacatc aagaaaattt
    43681 aagatgtact ttttagattg tatttagatt tataattata tagttaaatg aataacaaag
    43741 aattaatctt agtactatta aatataaaaa ttttttatat tttttctatc taaattcttc
    43801 tttgtttaat atatattgaa gagtatttat tgcttctaaa tatttttttc tgtcttcttc
    43861 agttaattta gaaagttttt ctcctaaacc atcacttaat ttatccataa aatcagttgc
    43921 tatcttatct ccctcttcag taatgtcaat tagatatttt cttctatcaa ctaaatctct
    43981 ttttcttgtt acatacttct tatcagttaa atcatcaacc atactagtta aactgccttt
    44041 ttctatattt aacttagagc ataaatcagt catacttatt actccataat tttttatgaa
    44101 aactaatgct cttaattgtg ttttatttac attataatct ggtgcaaatt tttttaggtc
    44161 ttctaagtac aggctagaat aaatcttagg aaatgttttt actaaaaaac ttatggtatc
    44221 ttttactata tagttcatat aatcacctcg gttgttttaa aatttattaa attatctaaa
    44281 taactttatt tcagtttaca ttaaaaatat tgcaagtaca atagtttttg ctgaatgttt
    44341 aaatttaatt agtaatctta tcattttttt atttttattt atattattcc tattaaatat
    44401 tatttatata gctattttat taaattcatg gtatagtaag taaagaagaa ctcttcacag
    44461 cgctgaagag aagacgctag cccattaaaa tggctatctt atttataaat aagatagccg
    44521 tttttaatta tattttatct gtacaattct atactcttag gtctacatct acttttccta
    44581 agtcttcctt ataatctttt atagcaggtt ctacaacttc atttacaaat tctacaactt
    44641 gttctggagc tctacctata aagttttttg ggtccattat agatagtatt tcttccttgc
    44701 tcattttaaa tgaatcatca ttcattataa gttcaattaa gttattatcc ttaccttcgt
    44761 gctttactct ataggcagct ttcatagaat attctcttat tatttcatgt aattcctgtc
    44821 tatctccacc tctttttaca gcttccataa gtattgtttc tgtagccata aaaggaagtt
    44881 cttcatttac acgtttattt atcatatttt catatactac taaaccatca gttacattta
    44941 tccctatttc aagtatagca tctgctgcca taaatgcttg aggtattgcc aatctcttat
    45001 tggctgagtc atctaatgtt ctctctaacc attgagtggc ttgtaccatt gcagggctta
    45061 tagattcaga gattatatac ttagataaag atgctattct ctcacttctc attgggtttc
    45121 tcttataagc cattgctgat gaacctattt gatttttttc aaatggctct tctaattctt
    45181 ttaaactttg taaaagtctt atatcgttag tcatcttatg catactttga gctatccctg
    45241 atagtatgct tattacttga taatctaact ttctagtata tgtctgtcca cttactgcat
    45301 aggaagaatg gtatcccatc tttttacaaa ttttcttatc taactctttt actttttcgt
    45361 ggtctccttc aaataagctt aaaaaacttg cttgagtacc agtagtacct ttaactcctc
    45421 ttaacttcat gttatctatt ctatagttta aatcttccaa atcaagaatt aaatcttgag
    45481 cccataaaca agctcttttt cctactgttg taagttgagc agcttggaag tgtgtaaatc
    45541 caagagctgg catatctttg tacttaagtg caaattcttt taaattgttt attaaattta
    45601 caagctttac tcttagaagt tttaaagctt cattcatttg tataacatct gtattatctc
    45661 caacatatgc agatgttgct cctaaatgta ttattccttt ggctttttca cattgtaaac
    45721 cataagcttt tacgtgagac attacatcat gtcttacttc tttttctatt tttctagctt
    45781 catcaaaatt tatattatct atattagctc ttagctcatc taattgttct tcagttatat
    45841 tgattcctaa ctcatgttca ccttctgcaa gtgcaaccca taaccttctc catgtagaga
    45901 atttaaattg tggagaaaat atataactca tgtccttgct acaatatctg tctgtaagtg
    45961 ggtttgagta agtagtatat ttattatcta tcattatatt agcaccttcc ttaaatcttt
    46021 tgtcgtgtga ttactgtgta cacattagta cataaataat tatatataat tttacgaact
    46081 ataacaagac ttttttattt tttgttcaca tttatatata gtatttttta tttattacta
    46141 ttttttattt atatccaaat tatctttttc aattaagtaa tccactattt cactatcaac
    46201 aaaatttaat acatacttat atctaattgc atagtattta tcactccatc caagctgatt
    46261 ttttacatca ctttcatctg ccccaagcct taaacttatt gctgcaaatg aatgtctaaa
    46321 atctcttgct gaatattgag aaagtccagc taaatctaat gcttttttga ctataagtct
    46381 gacatttcta tctgttatag aattactctt ttgagttgta aaaataaaat catcactagg
    46441 tattattacc tctggaagcc cagaataatt cctgtaatct tctaaaagtt taaaaaagta
    46501 tggatgtaat ttaactactc tttcttttct tcccttacct aaccttacat atgagttatc
    46561 gttttcatct accataaggt ctttccactt taagctaact aattcattta ataaacaccc
    46621 agtagtaact agacagacta ttattactct atctcttata tttaattttg gtaggatacc
    46681 tataagttta tttatttctt gtatacttag aacatcatct tttgttttta ttcttgttac
    46741 tgtgggtttt tctacatatc taaatggatt tatatctatg tatccttctt tttttaagaa
    46801 gttataaaaa ctatgtaaat aactatatat cttttcacaa gttgatttcg catatttagt
    46861 ctgtatatag tctacaaaat ttttacaatc ttctttcgta gcataaatca attctttccc
    46921 ttttaaaaat tctttaaaca gtataacctt tgataaataa tcgtgtttcg tgtttggatt
    46981 taattttgta gaaaaaacat taaaagtttc atactcataa tcatctagta tttttgtact
    47041 atacataata actcctttcc ttttcataaa ataaaatagc tatactttta ctataccata
    47101 tatttccccc tcaaatatac cccttattca atagataact tttaagttta ttttgttata
    47161 ttatgaaggt tttatgaaaa tatcaatctt ccattgtgca ctacacagta ctatggtatt
    47221 ataagttagt aaaaggtggc atttttttat taatctatga ataaaatatg ctactataaa
    47281 tttgtattgg aggtattttg atttggaaac atttagtttg cttgaaattt ttaaggcagt
    47341 cattttgggc atagttcagg gaataacaga atggctacca gtaagtagta cagggcatat
    47401 gatattagtt gatgagttta taaaattgaa tttttcaaat acatttataa gtacattttt
    47461 agttgtaatt caatttggtt caatattagc tgtacttgtt atatttttta gaaaattaaa
    47521 tccttttgat agcgcaaaga atattaagca gaaaaaagaa acagtccgtt tatggcttaa
    47581 ggttataatt gcagttatac catctggagt tattggaata ctgtttgaag atgatataga
    47641 tagattattc tttaattcaa cagtagttgc tattgctctt attgtatatg gtataataat
    47701 gatagggctt gaaaagagaa ataaaagacc taagtataaa gatttttctc aagttacata
    47761 taaattagct ctttgtatag gattattcca gtgtctagct cttataccag gtacatctag
    47821 gtctggttct actataatag gtgcagtatt acttggtact tctagatatg tagcagcaga
    47881 gttttcattc ttcttagcca tccctacaat gcttggagct agtgcattaa aacttctaaa
    47941 agctggattt ggatttactg gatttgaatg gcttatttta ggtgttggtt ctgtagtagc
    48001 atttgttgtt tcaattgtag ttattaaatt ttttatggac tatatcaaaa aacatgactt
    48061 caaagtattt ggttattata gaatagtctt gggtatagtg gttcttgctt atttctttct
    48121 attataatgt attctaattt aataacaaat gataaggaga aaagttatga gtgttaaaaa
    48181 agaaatattt gattggatta agtcaatagc tatggctatt gtacttgcat ttgtaattct
    48241 acaatttata agaccttcta ttgtaagtgg agaatcaatg tatcctactt tagatgataa
    48301 agattatctg attttaaata ggatatcata caaggttggt aaacctgaaa aaggcgatat
    48361 tgtagttttt aaaaccaatt tagttgatgg agaaacagga aagaaaaaag acttaataaa
    48421 aagagttata gctactgaag gtgacagaat aaaaatatca aattctaaag tgtatgtaaa
    48481 tggaaaatta ttaaatgaac catatataca caataactat acttctggag atatagatac
    48541 tgttgttcca aaaggtaaac tatttgcaat gggagataat agagaaaata gtaatgatag
    48601 tagattccct gatgtaggta tggttgatga agatgaaatt cttggtaagg ttatggtgag
    48661 actattacct cttgataata ttgggaaagt ggactaaaaa ataagagact gaattggtaa
    48721 agtttatttt acaaatctca gtctcttttt attttcttaa attacaaata tttttttact
    48781 aaatatcttt tgattctgta ataagtctta ttatatcact tgcttcttca ttaaaagttg
    48841 ttactatact taggtagtct gttgctctac tcatagctaa ataaacctta tttaaatctc
    48901 ctacaaagtc atttacttga taatcttgtt caatatcatt tatagtttga ttgtataaca
    48961 tctctaattc acatactatt accgctttat actctaaatt ctttattgca tatatatttg
    49021 ctattgtagt tcctaccttc ttacttatat ttgtcaaatt atcttctgca catatataag
    49081 gaatttttgc ctcttccaat gcttttttta acatatattg aaagtaaatg gtttttccac
    49141 tttttaattt cttcttatta taaggataaa cgatagcaac ttcagaataa tcaagacctt
    49201 ttttacttat taaatactca atttcccaga ttacagaact tatttggtca tcaaggtcac
    49261 ttacttttat tatatcaaca gacttatttc cacctctaag tgctttagta taaaagaaag
    49321 tactaaattc tgtatttggt cttaattcgt tgatatatga gttagaatta tttgaaaatt
    49381 tatttgtaaa atctacaatc tctttagctt gtctataatt tttacttaag ataatcttat
    49441 catcaaattc tataccatta tataattttt taaatatatt caatctatta gagatattca
    49501 aggagttaca agaacacgca ttaaatatga attttgtttt atataaaaac tcccttataa
    49561 aatctatttc atactctaaa aagctttctg cttcatcaat aaaaatagcc ttgaacatat
    49621 ttttattttt tataatgttc tgtgcttgtt ttacaagatt attaaaggtc ttttcgtaat
    49681 cattttttaa catgttataa tctacaatta aattgaattt tttagctagt ttaaatataa
    49741 aagaactaaa tgtgtgaact tctaaattgt tattatcttt gtataataac tctatcctct
    49801 ctcgaagctc attgcacaat tgttttgtat gtgtaaatat gactaattta tgatgtggat
    49861 atacttttgc taattttata gccctagaaa gcataattgc tgttttgcct ataccagaac
    49921 caccttcaat aagtgtattc ccatatttaa tagaaacaac atctttaatt tgaacgtctt
    49981 ccatcatagt tgctgtatac ttatagtcat cattgtagaa tgaaattttt ttaaattttt
    50041 catttagatg aagtttatca tttattatat agtattctga acatatgtct agtaaaaata
    50101 aatttaagtt tatttcatca ttctcatcat taagatactc ctccagcgaa cccttattca
    50161 ttatatcttg aagcttattt ttatctatta tattattatt aacaaattct tcaaattcat
    50221 atgtttcctc aacttcaacg tatggcataa tgtaaacgta gttataactt atatttctat
    50281 tcttttgtcc catttttagt ttcaaaagtt catattcctc attcataact tcaagtaact
    50341 cttcttctaa aataaaaaat atatcttctg ttgtatccat aaattttata aataaaattc
    50401 ttccatcttt aacatacaac aaatcggtat ttattccttt aaaaggagta acttttggca
    50461 ctactttaac gtcctcattg atattttcgt aaaatatttt ctcgaactcc ttcaatttta
    50521 gggcgtctaa ctgagaattt atatttatgt attggctcac ttacattacc tccttctgtt
    50581 atacttaatt ataccatttt gaactatatt tttatatata ctttttatag gcaaatttag
    50641 taaataaatt caaaataaat acaaataaat acaaaactgc taaaataatt ttgcaataaa
    50701 tatagatatt tattgttata gaatactttc tgtaaataat aaaatgataa atttcataat
    50761 taatgtttaa aatagtaagt aaagttttaa aaaaaataaa tcttgttgac taaaaataag
    50821 atttattata aaaaatttaa aaacctgcta aaaataatct attttcatta gcaggtttta
    50881 tttataatct tcttatatta atactattat atcctatttt tagattttac tgtagtattt
    50941 actatttatt ttgtagtaaa gtattgattt tacaacttca ttatatcaaa caaacttgga
    51001 taattatata aataatacat atataaagct ttattttatt aatcttttgt aagtagcact
    51061 tttagcactt agattatttt tgcattatat aaaattaaac ttaaacaatt taaaagccac
    51121 aagatatatt atcatatctt gtggcaaatt taaatttcta aaaatatttt cttattattt
    51181 agatattatt tcttttactt cgcatactct atagctcttg tttctcttat tatgcttact
    51241 tttatttgtc caggatattc aagttcatcc tctattttct tagtcatatc tctagccaat
    51301 agatgtattt cttcatcatt tatagcttct ggttttacca ttattcttat ttctctacca
    51361 gcttgtatag caaatgattt ttctacacct tcatatgaat tagctatttc ttctaatttt
    51421 tcaagtctct ttatatatgc ttctaaagtt tctcttctcg caccaggtct agcagctgat
    51481 attgcatctg ctgctgtaac taatacagcc tctactgttt gaggttcgta atctccatga
    51541 tgagtactca tggcatgtat aacttcttta gactctttat aacgtctaag taaatccata
    51601 cctatttcaa catgtgtacc ttccatttca tggtctacag ccttacctat atcatgtaat
    51661 aaacctgccc tcttagccaa tctaatatct gctcctattt cagcagccat tataccagct
    51721 atatgagcaa cttctataga atgtttaagt acattttgtc cataactagt tctatagtta
    51781 agtctaccta ataatcttat taattccgga tgaatcccat gtacactagt ttcaaatgca
    51841 gcttgttcac catattcttt tataatattg tcaacttctt ttctcgcctt ttcaaccatt
    51901 tcttcaattc tagctggatg tattcttcca tctgctatta atttttctag agcaattctt
    51961 gcaatttctc ttcttattgg atcaaatcct gataaaatta cggcttctgg agtgtcatct
    52021 attataaggt ctatacctgt taaggtttct aaagtcctta tatttctacc ttccctacct
    52081 attattctac ctttcatttc atcattaggc aagcttacta ctgttacagt agtttcggct
    52141 acgtgatctg ctgcacattt ttgaattgca tatcctataa tttctcttga tttcttatca
    52201 gcttcttctt tagcttgact ttctatctct tttatcatta tagacatttc acgtcttaca
    52261 tctctctccg cattggttaa gatgatttct ttggccttat cagaagtaat tcctgatata
    52321 ctttctaatt tttctaactg ttgagttttt attacttcga cttcttcttc tttcttttcc
    52381 actaccttta atttttcact taggtttact tctttagatt ctaaattttg taattttcta
    52441 tctaagactt cttctttttg tactactctt ttttcatact tttgtacttc tgttcttctt
    52501 tctctgtttt ctctttcagc ttctgttctc cacttatgga tctcttcttt agcttctagt
    52561 aatttttctt tttgtactgt ttctgagtcg tggtgtgctt tatctattat ttctttggcc
    52621 aagttttcag cttgtccaat ttttgcttca gatatatttt ttctaacaaa atatccagct
    52681 ataataccaa cagctgcacc tattacaatc attactacac tatctatgac atccacctcc
    52741 ttcgttaata atcccaaaat gtcatcacta tgattaaaaa atattcctaa taattaaaat
    52801 taaatttaga tattttatcc tcacttaatt ttataatttt ttcaacattg tgtcaagcta
    52861 atagggagcg tggcatgtct ttaattacta gttatttttt tgtattttta cttattcttc
    52921 tacaatttct tttgatactg aagtacctga ttcttcatgt tcttcattta aattgtaaaa
    52981 tgctctaact ttctcatcta tttcagtagt taaatctaaa ttatcttcca agaatttttt
    53041 aacattttct cttccttgtc caagtttagt atcattgtaa ctataccatg aacctgattt
    53101 tttaactata tctacatcag cagctatatc taaaaggtct ccaatttttg aaatcccttc
    53161 tccatacatt atatcaaatt cagcttgctt aaatggtggt gctactttgt ttttaacaac
    53221 tttaactcta gttctactac ctataacttt atcaccttgt tttattgtat ctatttttct
    53281 aacatccaat ctaactgatg aatagaattt tagtgcacgt cctccagtag tagtttctgg
    53341 gtttccaaac attattccta ctttctctct taactggttt ataaatatag caacacaatt
    53401 tgatttttta attgaaccag ttaactttct aagtgcttgt gacataagtc tagcttgtaa
    53461 acctacatga gaatcaccca tatctccatc tatttcagcc tttggaacta atgctgctac
    53521 tgagtctatt actattatat ctatcgctcc acttcttatc aatgcctctg ctatctctaa
    53581 agcctgttca cctgtatctg gttgagatat tattaggtta tcaacatcca cacccaaagc
    53641 ttttgcatat actgggtcaa gtgcatgttc tgcatctata aatgcagcta ttcctccatc
    53701 tttttgagct gatgctacac aactaagcgc aacagtagtc ttaccagaag attctggacc
    53761 atatacttca actattctcc ctctaggtag acctcctata ccaatagcta tgtctaaacc
    53821 aatcgctcct gttgatataa catctataga catagatgtt gcttctccca atttcattac
    53881 tgaaccttta ccaaaatctt tttcaatttt acctaaagct tcattcaacg cttttaattt
    53941 ttcttgatct acactcatct ctataccatc ccttcattta tctacaaaca tttgttctct
    54001 tgttatatat taattatata acataaatca aacctagtca atttaaaaac gctactaatg
    54061 attatatttt tattcattac attttattta taaaccatta ttaataatta tatacacaaa
    54121 agaaaatatt cttaaaatga aaagaggtat actataatag tatacccttt tttacatttt
    54181 taaaatttta agttgttatt ttttatttat taatcattag tttttattta ttaaagcata
    54241 attttttact tagaagacat aaaaagctct ttatttttat atagatattc ccatccagaa
    54301 tataatgtaa gtagtgtagc tataagaatg agaatttcac caatatttaa tatcaataca
    54361 ttttcaaact gagcacctaa caataaaaac actatagata ccatttgagt tatcgtttta
    54421 agttttccac tgtttccagc agcaattact tttccatcag cagcagctat agctcttaat
    54481 atgctaactg taagctctct agccactatt ataattacca tccaactact tacaagatgg
    54541 tcttctatca tacatgtaag tgctgaaata accaataact tatctgctaa tgggtccata
    54601 aattttccaa agtcagtgac tagattgtat tttctagcta tttttccatc taaagcatca
    54661 gtaattgaag ctattataaa aataatacaa gctattaaaa atttatttgg tacattgagc
    54721 aacataatta aaacaaatac tggtattaaa aatattctaa acaaagttaa cttgttaggc
    54781 aagttcatat aaaacatctc ccattaaatc gtattccatt gcatcattta tttgaacact
    54841 tacaaattct cctacttcaa gattgtctac actttttaca tacactatac tgtcaatttc
    54901 ttccgcatca ccttgtgttc ttcctgtata tacattatct tctatctgtt cttctattaa
    54961 cacctcataa gtttttccta tctttttgtc attaagttct tcagatattt tttgttgaat
    55021 catcattaaa gtatctcttc tttgtatttt tacttcttca tctatatggt ttggcaatct
    55081 atctgctggt gtatcttctt ctcttgaata tgcaaatgca ccaagtctat caaatttaac
    55141 ctcttcaaca aagtccacaa gttgtttgaa gtcatcttct gtttcaccag gaaaccctac
    55201 tattatcgta gttctaagta tagcatctgg tatattactt cttatcagat tgattttatt
    55261 taatatatct tctttagtag tttttctatt cattaatttt aaaatattgt tacttgcatg
    55321 ctgtattggc atatcaaagt aactacatat attatcatat ttctttataa cttgtatcaa
    55381 ttcctctgtt atagattctg gatatgaata cataaccctt atccacttaa atccatctat
    55441 ttttgcaagt tcttctaaaa gttctgataa tctttctttt ccatataaat caaaaccata
    55501 ctttgtcgta tcttgtgcta taaccacaag ttcttttact ccagattcag ctaatttctt
    55561 agcttcttta attatatctt caaattttct acttctatat ttacctctta gttttggtat
    55621 tatacaataa gtacaattat tggagcatcc ttctccaatt tttaaatagg ccatatagct
    55681 aggtgtagat atatatcttg gtaaatcttc attaaataca aactctatat cattaaggct
    55741 tacaatttga tgcatttcac ttaattcttt aagtatttta tctatatttt gatagcttcc
    55801 tgttcctact atagcatcta tttcaggaat ttcagttttt aattcttcag aatatctttg
    55861 ggctagacac cctgttacta tcaacaactt taaattgcca gtttttttta actctgaaaa
    55921 gtttattatc gtatctatag attcttgttt agctgactct ataaacccac atgtatttac
    55981 tataattaca tcagcttctt caaaatctcc aattaattta tagcctttgt tatttaaaat
    56041 tcccatcatt atttctgcat ctactaaatt ttttgagcat cctaatgatt ccaatgctat
    56101 ttttaacatt cactttctcc ttccaatata ctctcatata agtctataac atcttctaaa
    56161 gctttttgtg tatcattaaa atttataatc ttactatact tatatttctc tactgaatgc
    56221 atataaagtg ggtcgtagta ttctaaaaga tatcttttta caagttcttt atattcacct
    56281 gattctaata aatcaatata atcatctact actttattac ccaatctttt tctaaacttg
    56341 tttatacatt cttttaaaat caatatatta ccttcatctt tatcataaat ataatctcta
    56401 caaagtctat caactctatt ttcaatatca cattctaata atatatgatg tccttctcgt
    56461 gtcattgcct cgaaaatttc atttggaact gtaacacttc caactcgttt gctttcactc
    56521 tcgacaaata tataattctc tttcgaaaaa aatacacttt caaatagttt tgtttcaaag
    56581 ttcttttgag atggtggctt tttatcaaaa gttataaaac caaaggtaga accactgttt
    56641 ttagctatgc cttctaaatc cagtacatct attccttttt catctaataa atgtaacaaa
    56701 tcagtctttc ctgtaccagt caatccatga acagatacaa agttttttgt atccattaca
    56761 tgccttagat actctaatac aaaatttcta taagccttat atccaccttc aagttgatat
    56821 acatttacac ctaatgatga taataaattt actatacttc cacttctcat tccgcctctt
    56881 gcacaatata tgacaatatt atcataattt aatgcaagtt ctgctgcttg taaatatata
    56941 tcctttaatt tatacgatac atagtcaaac cctttttgta ttgcttcatg ttttccctgc
    57001 atcttataaa ttgttccaac ttcattatgt tcattatttt taaaaagagg catattgatt
    57061 gcattcaata tatggtcttc ttcatattct ccttcagttc tcacatctac aaatattact
    57121 ttatctagct taagtgcttt ttctattttt ataactgaca attctattca ccttctaaat
    57181 tctgcaaatc ctgtttgctt attaatacct ttctaggttt acttccctca cttgctccaa
    57241 ttatgcctct ttcttccata gaatctataa gtctagctgc tctattgaat cctattttaa
    57301 atcttctctg tagcatagag gcagatgctt gaccactttc cacgacaaat tctatcgctt
    57361 cactcaaaaa ctcatcatca tcactactct ttgaagtatt aaccttagat atagtttcaa
    57421 ttatatcttc ttcatatttt attccatctt taacctgact ttttacaaaa tcaattactt
    57481 tttccgactc actctctgat atgaatgccc cttgaagtct aactggtttt gctgcaccaa
    57541 gtggatagaa taacatatca cctttaccta gaagcttctc tgcaccaccc atatcaagga
    57601 ttgttcttga atcagtttga gatgatactg caaatgctat tctagatggt atattagcct
    57661 ttattacccc tgttataacg tcaacagatg gtctttgagt tgctacaatc aagtgcattc
    57721 cagcagctct tgccatttga gctaatctac aaatataatc ttctacatca tttgcacttg
    57781 ccatcattaa atctgctaac tcatctatta ttattactat tttaggaagt ttttcttccg
    57841 ctttctcatt ataacttgtt acatctttta cttgagcatc tgcaaataat ttataccttc
    57901 tattcatctc tgtaactgcc caatttaaag catttgcagc ttttttaggg tcagtaacta
    57961 ctggtatcaa tagatgtggt attccattat aatttgcaag ttcaactact tttgggtcta
    58021 ttaatagtaa ttttacttca tcaggatttg ccttatataa aatactactt attaatgtat
    58081 ttacacacac actctttcct gaacctgtag aaccagctat tagtaagtgt ggcatcttac
    58141 ctatatctcc aattataatt tttcctgcta cgtcttttcc aagtcccatt gcaagaggag
    58201 agttaaaatt attaaattct tcactttcta gaacttctct cacaccaacc atttgagctt
    58261 cttcatttgg aacttctatt ccaattgcac ttttaccagg aattggggct tcaattctta
    58321 tacttttagc tgctaaactt aaagctatat catcagttaa atttacaatt ttacttacct
    58381 tgactcctgg acttggttgt atttcatatc ttgttatagt aggtccaact gtaacttgat
    58441 taatttttgc ttccactcca aaatctgata gtgtcttttc taaaagagaa gcatttttca
    58501 acactttctt tttaccattt tcatcagact tcttatttac tttatttaaa agctcaatgc
    58561 taggcttttt atagtttgaa taatcctcat taactggctc tgctacaata ctcataggtt
    58621 gagttttttc tatatttaaa ttagatttag ctatatcaac ttttttttct ggtttagtat
    58681 ctacaactgg attttcattg gtagcttttt gtaattcttt taaaacatct aactctggca
    58741 tactttgagt tccttctaat atttctaaat actcatcttc tgccttatta aatccaacta
    58801 tttttatagt tttatcatct acaccatcac tattttcttc ttcaaaatat tcatcttctt
    58861 catcatcatt attaagacct tttgacatta accctttaaa gaaacctggt tttttattta
    58921 tagtagtatc atctacttca tcagtcatca tatctattgc agattttttc atatttgcaa
    58981 ttttatcttt aaacgttaaa ttgctgtctt tagatgcttt agattttgat tttgcatttg
    59041 acaccaaatc ttttatagaa atattaaata taaacattac agaaagtata agtgcgaaga
    59101 tacttattaa ccatccacct gctataccaa atattttact catataatac gcaatagttg
    59161 ttgctatcaa accactacct tgtccactta cacccaattt cataacatca tcaaacatgt
    59221 taccttttag tgggctatct acaggaagag ttcctgcatt taataatcca taaaatacaa
    59281 atataaataa aataattatg tagtatagtt tagtctttct tagcctatat atatattcat
    59341 ttccatcaaa aaatcctaaa agtcctgtta taattactat aaatggtatt gctattgaaa
    59401 gccctccaaa tagtccctta aaaagatttt gcattaacac aggtatccat cccatagaat
    59461 tagaatttaa actatataat aaaaatacac ctataaatat tgttattaaa ttatgatatt
    59521 ctgcattaaa acttaaggta tttaccttct tttttttctt ctttttcgtg gccattaata
    59581 tcactcctta tttttagcaa gttttacccc ttcacagcaa aaagtgctaa tgccttaaca
    59641 ctaacactcc tactttatta catcattata tcataaattt tattatttaa acaaatttta
    59701 atcattattt ttttcttcct cagattcttt tataagctct cttaattttt taagtgcttc
    59761 ttttagtcct ccaacttcat ctataagacc ataatccaca gcttcttttc ctattaatac
    59821 actaccaaca tcacttacaa gttcatcttt ttcatgcata agtttttcaa gtacatcttt
    59881 tttgatattt gatgttctta ttataaattg aattattcta tcttgcatct ttttaaaata
    59941 ctcaaaagtc tcatttatac caatcacaag accagtagtt cgcactggat gtataatcat
    60001 ggttgctgtt ggtgctataa atgagtaatc tcctgctgta gcaagaggaa cacctatact
    60061 atgacttcct cctagaacaa gagtaactac ttttttagat gtactgttta aaagttctgc
    60121 aatagctaaa cctgcttcaa tatctcctcc aacagtgttt aaaacaacta acactccttt
    60181 aacatcatta ctttcctcaa ttgagtatag cattggaatt atatgctcgt actttgtagc
    60241 ttttttttga ggattcccta taaaatgtcc ctcaatttct ccaattatag ttatacattg
    60301 aatatcttta ggaggttgag gtggcatttc attggtacca aattgcttta tacattctct
    60361 ctcttcgcaa ctagattctt cactacaatt atctttatca aatctttcat tatcttctct
    60421 ataatctttc ataaaaaaac tcctatcaaa attatattta atttagtttt accaaataaa
    60481 tcaaatatat taagatatat atgaaattct taaatttgat taaaaaataa ttgtattata
    60541 cagtttattt taaataaaat tgttggtgta tagcatgtac tgctgtatgc atatcttctt
    60601 cactaactaa acaagatata gtcatatttg agtctgatgt ttgtaaaaga gatacccctg
    60661 cttttgataa tcctctaact acctttgaca tgataccaga catttcatca gcaattcttg
    60721 aacatatcaa tgttacctta gcacagtctc tatttacttc ataatctaat tcaaatttat
    60781 ctagtatttc ctttaatgat tttatatcag catcttctac aacaaatgct ttttctgata
    60841 taaagaaatt tatcatatct atagttataa gtttcttttc tatctcattt aatacttctg
    60901 taaacacttc ttctgctgac ttaatcttaa cttgtgctac actatcttta tttgcaacag
    60961 caaccttaaa atctctttct tgttcatatt ctatattgtc ttctaagtgc ctacataaag
    61021 aacctatttt tgtaccttca aaagttggat tcattgtatt ctttatggct aaagttatat
    61081 ttccactttt agccaactgt actgctcttg gatgtattac ttttgcacct ttgtcagcca
    61141 tttggaatac ttcctcataa tctataaaac tcaatacttt agcgtttggt tctactctag
    61201 ggtctgcagt cattatacca tccacatcag tgtaaatttc aactgtttca cattctaaag
    61261 ctttaccaat agcaactgct gatgtatcgc ttcctcctct tccaagagta gttatttctc
    61321 catcatctgt tacaccctgg aatccagcta taactacaac cttaccatca tctaaagctc
    61381 tttttacctt tttaggattt atatacttta tctttgcatt agaatattca tcacttgtaa
    61441 ttatacctgc ttgctgacca gtaaataaaa cagaatctat cccctgtgca ttcaataaat
    61501 tagcaagaat tgttcctgat attatttctc cacaagacat tattaaatca agttctcttt
    61561 tacttggctc atcatttact gcactacaca aatttataag tgtatctgta gcatatggag
    61621 ctccttttct tcccattgct gaaactacta atactaattg taattcttca tcattttttt
    61681 tgtatgcttt tactatctta catacttcat tcattttttc atatgattct actgatgtcc
    61741 caccaaactt ttgcactaaa atactcattt tttcctccta aatatatccc tcatattcta
    61801 taattatcat gtcattacct atttttttta catttctcca tggtacttct aaaaatgact
    61861 tatcttttct tctggcaaaa aatccttttt cttttggaat tagaagcgct aatataccgc
    61921 ctgtagtttc atctagtata aggtcacatt ctccaatgac ccccaatctt tctcctgtga
    61981 ccaagttaac tatttcctta cctgctattt cagataaatt catattttat acctccagag
    62041 atttactttt ttcaatatta atccaagtgt agaatctttt ctacatctct tccaactata
    62101 catgtaccaa tattttcgat attgaatacc ttatcaacaa tcttctttat tgaattaata
    62161 ttaacattat ttatacattc aagtatttca tctgtagttt ttactttttt actaagtaac
    62221 atagatttac cagtagacat cattctactg ctagtacttt ctaaatccaa tatataattt
    62281 ccttttaact gttccttgct ttcagatatt tctttttctg taagatagtt ttctcttata
    62341 ttttcaattt ctttctttat taaattatat acatcttgta aattttctgt actcatgctt
    62401 gcaaatatac ctaattcacc acatttccta tataatgtct gtgatgagta tattgaatat
    62461 actaaacctt tttcttccct tattttctga aaaagccttg agcttatact tccaccgaaa
    62521 atattattta ccactgccat tgaatagact tcttcatcat tttcaaaagg aatacctttt
    62581 aggcacatag ctaagttcac ctgttcagta tctttatttt ttgatataaa gcaaggatta
    62641 aacttagcct cacttatgtc tatacttaaa attttctttt cccagtgtcc aaattttgat
    62701 ttgattttct ccaccatatc atcaaagtta aagtttccag ctatagaaat aacagcgtta
    62761 tttggaatat aatacttatt taagtattct aacatggatt ctctagttat attgtataga
    62821 gattcttttg tcccaattat attcattcct aatccatcat tagcatatat attttccact
    62881 aataaatcat aagataagtc atctggagag tcttcataca tcttaagttc ttccaatatt
    62941 ataagtcttt ccttatctat atcattttta tcaaatttag aatttagtat catatcactc
    63001 aatacatcaa ttcctgtatc tatatgctca tctattagtt ttacataata acatgtacat
    63061 tctttacttg taaatgcatt tatttgacca cccaaattat ctattgaact agcaatctct
    63121 tttgatgttc tgtttttggt tcctttaaac atcatatgct ctataaaatg agaagttcca
    63181 ctcacctgtg cttcttctat cctagagcct gcatttatcc aaatacctaa tgttattgac
    63241 tttagatatg gtatttcttc accaattatt gtaagcccat tttccagtat ttttgtctta
    63301 tacattacat tctcctaaca atttattctt tgtttcatat tggattattg aaaacactat
    63361 gttttaatta tatttatttt ttatatgtat tacattataa gtcagtcttt taattaattc
    63421 aactacaact tatacaatct taaccaaata tttatacttt gtctacttaa atacatcact
    63481 aagttttcct ggttttagtc ctttttctct tacaatagct ataatatcat ctatacattt
    63541 tgtcgttgcg ttggttggat gcattaagat tatactacta tctttaatgt cttttttctt
    63601 cattctatca atgattgcct ctggttggtc tttgtatttc caatctatag tatcggcatc
    63661 ccatttgata gaagtatacc ctaatgcttt agcagccttt actgtttctg gaccaaagga
    63721 acctgctggt gcttgaaaaa atttagtttt ttcacctata atttcttcaa ttatcttttt
    63781 agaggtctct atttgctcat aattgtcttc atatgataat gtagaataat ctaaatgttt
    63841 atatccatga ttacctattt catgtccttg tttttttatc tttaataatt catccttatt
    63901 cttttctgcc cattttccag ttacattaaa tgtaatcttt acattttctt ttttaagtgt
    63961 ttctaaaatg gattctacgt actctgtttc ccatccaagg tctatattac aggttaatgc
    64021 aacatatcca cttttatcct ttgtacctct ttcatatggt aaatctacac cattaaataa
    64081 attaaatact ggcttgttgt taaataactt taataccatt acccctcctg ataatactaa
    64141 taacactact aaaattagta ttatgatttt tttgagctta ctcttattaa gtaccatcat
    64201 tatcattaaa actcccccta attatgtaca aattgtttct tatttaatac tattaaaaat
    64261 aagctctgtt tatgcactaa atataactta agtgattcta tatatatcaa taaagctttc
    64321 tattaatcag cttttaaata gcttctttat aagagtaaag ccttacagaa aaagaactat
    64381 aagccatcca taactatcat tttaaaatta tctacttttt tgtatttaaa aaagcaaaat
    64441 cctaagactt tgcttttaat tatataataa gttatttatt tttatgttct ggttttggta
    64501 aaagaacttt tcttgataaa ttaactcttc ctttttcatc aatctctgta actttaactt
    64561 caacttcatc ccctatattc aatacatctt caactttggc aactctttca tgagctatat
    64621 gagatatatg aagtaatcct tcttttcctg gaagtatttc aacaaatgct ccaaagttca
    64681 ttattctact taccttacct ttataagttt ttcctacttc tggttcaact actatattat
    64741 ttataagttc ttgagctttc ttaatcatat caatctcaat acctgatata aatacttccc
    64801 cagtttgttc aatatctatc ttaactccag tttcgtctat tatcttagtt attatctttc
    64861 caccaggtcc tattacatct tttatcttgt caggatttat ttgcatttta acaatcttag
    64921 gtgcatatgg tgaaagttct ggttttggct gagatatagt ttttctcatc tctcctagta
    64981 tatggattct accctcttta gcttgtttta aagcacgttg tagaatttct ttatctatac
    65041 catcaatttt tatatccatt tgtattgctg ttataccata ctctgttcca gctactttaa
    65101 agtccatatc gcctaaatgg tcttccatac cttgtatatc tgaaagcact gcaaccttac
    65161 catcatgctt tataagtccc attgctatac ctgcaaccat atcttttata ggtacacctg
    65221 catcaagtaa agataatgtt gagccacata cacttgcttg agatgtagaa ccatttgaac
    65281 ttaatacttc agaaactaat ctaatagcat aaggaaattc ttcttgagat ggtattactg
    65341 gtaataaagc tctttctgct aaagcaccat gtcctatttc tcttcttcct ggtcctcttg
    65401 atggtctagc ttctccaaca ctatatgcgg ggaaattata atgatgcata tatctcttgt
    65461 tttcttcttc atctaaccca tctaattttt gaacatctcc taaagcacct aaagtagcaa
    65521 cattaagtac ttgagtttgt cctctagtaa atatggctga accatgagct ctaggtatca
    65581 tgccagtttc acaccatata ggtcttattt cttcaagttt tctattatct ggtcttacat
    65641 tttcatgtac tataagtttt cttacttctt cttttattat atcttgtaat acttcttcta
    65701 tatctccaac aaaatcttca aaatcttcta aagtttcttc aaagtgagct aaagtttctt
    65761 ctttaactct atccatattt tccattctct ctaacttttc aaaagtctga actgcttttt
    65821 tcatcttatc agttgcaaat tcgcgaacca attgagttat ttcttctcct gcatggtata
    65881 attcaacagg cattttttct tttccaactt ctgcaactat accttctata aactcaacta
    65941 ttttttttat ttcttggtga gcaaataaaa tagcatcaag cattacctca tctggaactt
    66001 catcagctcc ggcttcaacc atcattattg cttcctttgt acctgaaaca actagatgca
    66061 ttgaactttt ttctctttgc tctgcgtttg gatttacaac aaatgcacca tctacaaggc
    66121 caacacatac tgaacctgtt ggtccattaa atggtatgtc tgatatagaa agggctattg
    66181 aagaacctat cattgctact atatctggtg tacaatcttg gtctactgat agaactgttg
    66241 caactacctg aacatcattt ctaaatcctt ttgggaataa aggtcttatt ggtctatcta
    66301 tcaatcttga tgtaagtata gctttttctg aaggcttccc ttctctcttt aaaaaacctc
    66361 caggtatctt acctacagag tataattttt cttcataatc cacacttaaa ggaaaaaagt
    66421 ctattccgtc tctaggtttg gctgatttag ttgtatttac cattaccata ctgtcactgt
    66481 atcgaactat acaactacca ctagccattt cacaaatctt tcctatttct acagaaagtt
    66541 ctcttcctgc aaaatccatt ttaaatattt tatgttcaaa cattaatgct tgtcctcctc
    66601 ttattaaaaa acacgtatat cactctattt actatattat caaaaatact ataaattaac
    66661 aatataaaat tatcttcaca tatatatgca aaaaccttat attactacta attagaacaa
    66721 cttatagcca atatatctgg ccctgtatga gagcaaatag aaactcctcc tcgagtaaat
    66781 aatactcttc ttgcttttat tcttttattt acttcatctt ttaatatttc acaatcgtgt
    66841 aaattatctc cacaacctat tgtgacgatt tttccttcta aagacccttc attcatttct
    66901 aaaattatat cgaccagttt acttgctata ttctttattc ctctaacctt atttaccaac
    66961 ttagcttccc cattatcaaa gaaaaatata ggctttatat ttaacatatt tcctatcaaa
    67021 gcagttgcaa ctggaactct tccactctgc tttaaaaaat caagtgtata tggtgcaaaa
    67081 agtaatctta cactactgcg agtattttct aattcatcta taatttcttc aaatcccagt
    67141 ccttcttcaa gaagttcaca tgcctttata acatattgtc cactacctag agataaattt
    67201 ctagtatcaa atatatgtat tttttcattt tcatttacat catttttagc tatcatagca
    67261 ctttgaaaag ttcctgatgc gtttgcagcc cctgtcatac agattatatg ataaccttct
    67321 gttatgaact tatcaaacac ttctttaaac tccatatatg tagcttgtga agttttaggt
    67381 atttgcttga tttcttttac ttttttataa aactcttctt tctttatatc tactccttct
    67441 atatattccc tatcattaaa aataactgta agtggaacta tctctatata atctttttct
    67501 gatatttcat ctggaatatc gcacaaacta tcgcatacta actttatttt caaaataata
    67561 tcctccttat tccaactaat tatcctgtta taaaatttct atatttatcc tgtctttcct
    67621 tttaaattga ttatgtattt gtatactatt ttaatattct tacccaatat tattcatttt
    67681 ataatttttt ataacatata aactactttt attattaact attttacttt ataatgaatt
    67741 aactataaaa aagcaggtat acactatacc tgctttttta taaagaatga aattactttc
    67801 ttaatcctaa tttagctatt aatgctctat atccttcaag atctttttcc tttaagtaag
    67861 ctaataagtt tcttcttcta ccaaccattt ttaatagtcc tcttcttgaa tggtggtctt
    67921 tcttatgagt ttttaaatgt ccatttaact cgtttattct agctgttaat aaagctattt
    67981 gtacttctgg agaaccagta tccccttcag ctcttccata ttcttttatt atttctgatt
    68041 tgtttatcat ttagattacc tccgtatttt tttagaaacg cctattacta agcattgatt
    68101 ggagtattca aatgccgagt aatggttatt ttccttaatc attttatcat acattacttg
    68161 tttttgcaaa catagttttc atacacataa tttgtatcat tatacaattg attttttaag
    68221 tcatctattg aattaaactt tctttcatct cttattcttt ccaaaaattc aacaattata
    68281 ttttccccat aaatatctct atcaaactct aaaatatttg tttcaataga caaagttttt
    68341 ccattaactg ttgggttata gcctacattt gtagcaccaa aataagtctc atctccaata
    68401 tgtacaatag aagcataaat acctctcttt ggaacgagca tattattctt aaggtcaata
    68461 tttgccgttg ggaatcctat agttcttcca aggtgtttag aatgtataac acaaccttct
    68521 aacttgtaat ttctacccaa atattccttg acattagcca tatcaccctg ggatactaaa
    68581 cttctaatat aagtactact cactcttaca tcattgattt tgatgggttt tattacttct
    68641 acctcaaaac caaattcatg ttctaagctt tttaatagat taacattgcc ttcttttgcc
    68701 cttgcaaatg taaagtcatg tccaattact atctttttag cttttaattt ttttactagt
    68761 atctcatcta cgaaatcctt tgcaggtatt ttagtcatat actcatcaaa tggtatgatt
    68821 acaactatat ctattcccaa atcttctaat aattttattt tatcatcatt gcttataata
    68881 ttttttgttg agtttggtct aaagtaattt acaggatgat ttgcaaatgt aaatacaata
    68941 ctctgtatat tttctttttt tgcatattca actgtttttc ctataagaac ttgatgtcct
    69001 ttgtgtacac catcaaaatt tcctatggta atgacacttt cttttatgtt tgctatttct
    69061 tttatagatt ttataatcac cataataaat gttccccgct aaaatataat ttactcttaa
    69121 cttattcaca aactattata gcataagtaa aagagataga ctatagaagt tattatagta
    69181 ctatctcttt tgttgttttt ttaaatacat tggttatatg aacatcttat cacttttaac
    69241 acttattgta ttattgtgtt ttgataactt tcctaatcct aagaaattat ctgtactgta
    69301 tactcttaca acttcatcat ctttatcgaa attatttttt aaaaaccttt tatcatctat
    69361 tgagccacca ttactataat attttatagc attagggttt aatacaacat aattaaacga
    69421 atcaaggaca taatctatat catataagta tttgtctaaa gttttatttt cataaaataa
    69481 ttctaattct tctaatgtta ttgaattatc taagtcaaat ttaccagaag atgttctatt
    69541 caaaaacgac atatgagctc cacaacccag atattctcct atatcatggc aaatacttct
    69601 cacataagtc cctttagaac actcaacata aaacattact ttattacctt ttatacttag
    69661 tatttttatg tcttttatat ttactcttct tgtttttaaa gtaatttcag attgtctacc
    69721 acttcttact aaatcacaca ttctctttcc atttaccttt aaagctgaat aaattggagg
    69781 aagttgattt atctctcctc tttgtgtatc aaaagctctt tctatgtctt cattactaaa
    69841 tttaaaatca tcaacttttt ttaaaatttc acctgaagca tcataagtat ctgtacttat
    69901 acctaaagta agctcacata tatacgattt atctttgttt aaaataactt cacatacttt
    69961 tgtagctttt cctatacaga ttggtaaaac acctgaagca tctgggtcaa gagtacctgt
    70021 atgaccaact ttttttatat ttaaaatctt tctcactcta cttacaacat catgagatgt
    70081 catacctgtg ggtttcaata tacttataat cttattcatt ttactgtcac cttaaattga
    70141 ttttaacact gcctctagta ccattttctt tgcattatca atactatctc taatagtaca
    70201 tccagcagcc cttacatgac caccaccgcc aaataacttg gctatttcac ttacatcaac
    70261 ataatttttt gacctaaaac tcactttaat ttcattttgt tttttctctt taaataaaat
    70321 tccaacttct atacctttta tgtctcttgt atatgttgtt attccatcaa catcattaaa
    70381 gctaatatta tttctattca tcatgtcttg agttaaaact atactagata cctttgactg
    70441 aacctcccat gactaaagtc acagggttcc tgcttcacag aattttgcat a
//
LOCUS       DACTZW010000008        70444 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.008, whole genome shotgun sequence.
ACCESSION   DACTZW010000008 DACTZW010000000
VERSION     DACTZW010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 70444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 70444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..70444
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.008"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            121..342
                     /locus_tag="JAM15_02905"
     CDS             121..342
                     /locus_tag="JAM15_02905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797225.1"
                     /translation="MKSNKTLLQPLCKEIILEFSKKTVKNLEVSMGYLYTSETYKLIS
                     EVVSDMSCKGNLFRFINCHNSTEGIRYAL"
     gene            1444..2721
                     /locus_tag="JAM15_02910"
     CDS             1444..2721
                     /locus_tag="JAM15_02910"
                     /inference="COORDINATES: protein motif:HMM:NF015983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HAT6797226.1"
                     /translation="MLNTDNTIELDYKNKIIKHKNNMHFIYDKISKRKIFVSDEVLNY
                     IVSAEKLKLDESSFINCFENKDDKIYIRELMVMLKKVGFIKNENYNIELSKINNLNFR
                     SVHLLLTNRCNLKCKHCSSNCEPDGEDTLGTDEIKNIILNLKETNPKRIVFSGGEPLL
                     RHDFEEIIRYAKTLLKNTKFSLSTNGTLINENNVVMIKELFNCVDISVDGIDEDSCSK
                     VRGNGVFNKVIKSVYLLKKNGVNDISLSMVFGVNNTNMKDEFIELNQKLGTTPIVRAF
                     IPKGRGYQNKELFNNGDVKFPMLIANIYNDKTKTNSTRINTCACDAFENSLYIDANGD
                     CYPCPSLNLDEYKIINLAKENIKIEYVKNRMGVLKREFLNVLDYKGTKCEICDINLFC
                     WNCPADFINAKKNNEIDFWCDLTKENLEAIVWG"
     gene            2732..3775
                     /locus_tag="JAM15_02915"
     CDS             2732..3775
                     /locus_tag="JAM15_02915"
                     /inference="COORDINATES: protein
                     motif:HMM:NF015983.1,HMM:TIGR04085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HAT6797227.1"
                     /translation="MNFTIIVTSKCNLRCDYCYEENKKYQDMSVEVCDKTIDFIIKSI
                     RARKNINESHKVVFHGGEPLLKFDLIRHIKERLDNELKYKYKISYMMTTNGTVISQEI
                     INYIKENNIALSVSVDGTKCTHDKYRRFESGKGSYDIVYKNVAKLIQNEINIRCRLTY
                     RSLTVSELYKGILELSSLGIKNFVPVADFYDTTWTKEDIDVLESEIDKMICDNKYKDL
                     RVSMINQERLCEKQSDCFGGIVSFTISEDGGIYPCTFVIGNEKFRIGTVYNDDCIDKE
                     YSLELFYERFEESEPCKTCSAKEYCMGNKCKLINYMANGKYYEPSIINCNLMSVNLRT
                     YNKLLKGGELGAL"
     gene            3765..4988
                     /locus_tag="JAM15_02920"
     CDS             3765..4988
                     /locus_tag="JAM15_02920"
                     /inference="COORDINATES: protein motif:HMM:NF015983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HAT6797228.1"
                     /translation="MHYNKYFIKDIAQISEEKHIAYIGNKMTGDWIKIPKICMDTINY
                     SYENKILVGDTIKFYEDEDDKIYYKKILKNLDNMDLLSTCYIEKAVLNRLEKVTFALT
                     EQCNLKCNFCSMDSHIDKNEEIDYDTVIRIIRNIMKLKPKKLILTGGEPLMRRDFLDI
                     LKYIKDNYETKVQLMTNATLIDESIVDKLTSNLYAIDISIDGYDKESCDSVRGKGTFD
                     KINHSIDLLKKKKFRNISLSMVLGEHNYNTVDKFNKFCEDKELKAVSRYFIRMGRGEY
                     NKVYLSNEKDIMFIPNIDYRPYLRCHTCKPGITQIYIDYKGDVYPCSLLRDSKYKMID
                     AIKIDSSFVSNIFNKELKVYKEIEKLSTLNYFKCKDCKNKFFCNNCLSIMDTLVNDDD
                     LFTHNCNKIKEIINI"
     gene            5115..5303
                     /locus_tag="JAM15_02925"
     CDS             5115..5303
                     /locus_tag="JAM15_02925"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797229.1"
                     /translation="MKKLNDELKVNKIINKIEVKDMEINADPCKVYWEEHGLLHEEDC
                     DKDCGTWPFLSPEASVKY"
     gene            5384..8086
                     /locus_tag="JAM15_02930"
     CDS             5384..8086
                     /locus_tag="JAM15_02930"
                     /inference="COORDINATES: protein motif:HMM:NF014717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6797230.1"
                     /translation="MYIILKYKIYNEVVINMMTKLLKGYFIKNRNKFFIIVFAIAVCT
                     MIIFANKVSKNSQSNYVVKETVKQMADYQAKFKNVSKRDLDIIKNSEDIKNTIVSKYY
                     GDIKTEQNFYKLESYNSDSFKELKNTLIYGHYPRGKNEVIIDLSFFELLKSQGKINMP
                     DDNKFKEIYVDFRYIKEYQNNKEEEVLLDETQNFKIVGVYDFSQMMKRYKDDGFSVYV
                     HSDFDYPSVAITYNGYINLKNGFKGYTSKTNKLQGELTSTKSQLTINEDRQMALSDNS
                     SSLTTLDKFDKGIIIASLVIIFNVFSIMSREIIREIGLLRIVGMSKKQSFILLFIKNL
                     ITLITGLTIGFLLGCILSVFMIRYMNFDSSMLIDPRKAPILITTKSITNTIKTITYMF
                     IVSTIVPVLSIIMSYPIDMISGKLKFDLRIENKVLSKLKIYKKMKNKVTSIVYKYSDN
                     IKHNNRNMKMYNSKYIKMKLAMKNSKRNLVYIITTGILVAMSGLYIVSIFIDNQSSLV
                     DNNPLLLKLGDYDIDLNYIGSDSILGRGITEKEINELNNIDGIESIYSVKRRVAFSRL
                     NTKDLSKAMKTTMFLNGKDKEIDYGIDLLSINEDASKNLLNDYKGLIEKGQMFAPNRD
                     IPEVVIFNKIEDWSSGSRNLVDANKKYKLGDIIDVKISMQENGKLVYKTVKVKVVGFL
                     SDKWEGVNEGLSNYPDIVMDSSDFKKITGENTYDEIKIKVNPDKLETVKESIENRVKD
                     NKSIKYDDRSSIEKEITQYRWINTVRELFNSMLFAFTASINIFFSVITSIEVRRKEFG
                     IMRSIGLSLKDLKGILIREGLIYGIFSSILGLIFIFNYGVKLSSMLKRMSEHKHIEYS
                     GSWYILPMYPTLIFIIVTILICLLAVALTFRRLSKNIVDQIDDI"
     gene            8103..9854
                     /locus_tag="JAM15_02935"
     CDS             8103..9854
                     /locus_tag="JAM15_02935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002845875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6797231.1"
                     /translation="MMKKDKNLKRFLKFIISKNKLKLSISFFLVIVSSCMSLYLPKIT
                     RKIVDEGIMAKDYKFLLNLIIIYLIIVFSSAIIDIILEYLYNVMKNKVTSSFKIKLFH
                     HLSKLSGKYFSNIKSGNIFSIVEQDLYIVEGFNAELLFSIIMNFITAICSVYFLFMMS
                     KDMLFIVVILQILLILSQSKIRKLISKMTREIRNLDGNLANISQEYISNIMNVVISKS
                     KKIFLKRYIKQMKSIIEKNMIINLIMVSNISISKILSGMISATIYGYGGYKIISGKLS
                     IGELIAFQQYTGMLVNPCINIIRSANKIEQVKVSIDRIYSIIDEPIEIFSPLKSNIFG
                     SNLEHKPIENIEFKNVYFKYSDKDNQVLNGVNLSFSKGKTTAIVGGSGCGKSTISNLI
                     YRLWDVSEGEITINGINIKNVNLAFLRKNINVVTQDVLIFDNTIRDNISLGKNIEDEE
                     ILSICNIVGMKDFIESLEDGLYSIVGEKGVKMSGGQKQRIAMARALAGNSDILVFDES
                     TSSLDNISQKEIMKNMKEVIKDKIVIIIAHRLSTIKDADNIYVIKDGQVAESGSDEEL
                     IILGGDYSLQCSGGDVH"
     gene            9851..10861
                     /locus_tag="JAM15_02940"
     CDS             9851..10861
                     /locus_tag="JAM15_02940"
                     /inference="COORDINATES: protein motif:HMM:NF012311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HAT6797232.1"
                     /translation="MRKVKIAVVDTGIDIDDEELKNFYHIDERFQLNNDLDVRDSNGH
                     GTLVSKTIIDICKDVELYPIKIFDELGKTYSLNIVIVLKKLINSDIDLINLSASTFDY
                     SYEKELRDVCKELQNKNKFLICSKHNKKSDCDSIPTVFDSVIGVCGHEYIFYKNDYIY
                     RAGEKVKMYTNSKDIFLSFNKKITHFGRNSKSCAVATGIIANLIKKYNYIEFKELERI
                     LKKNSQSEKSLNIKKISNIKDNKIKFQNHKNIKYEDVHNIEERVLNIINNKFSSNVKL
                     PDIKKYGIINNLTNIGLYNAYEFLEYINNEFSIDINYKDIYIYNLSDLNLLKIIIRKY
                     LN"
     gene            11051..11716
                     /locus_tag="JAM15_02945"
     CDS             11051..11716
                     /locus_tag="JAM15_02945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014967018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6797233.1"
                     /translation="MKLLKVSNLKKIYGKGNNEVIAINNISLEIQPHKFTAIVGQSGS
                     GKSTLLHSMAGLDKPTEGNIFIDDLDMYTLNDDKLSKIRREEFGFIFQSFNLIPVISV
                     YDNIILPVSISNKKVDTKYIDILINKLGLENHISKFPNELSGGQQQRVAIARALANRP
                     SIIFADEPTGNLDSKTTDEVIDILKVCVKEFEQTLVMITHNNEIAKMADKVITIKDGQ
                     VIN"
     gene            11880..12635
                     /locus_tag="JAM15_02950"
     CDS             11880..12635
                     /locus_tag="JAM15_02950"
                     /inference="COORDINATES: protein motif:HMM:NF012301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6797234.1"
                     /translation="MSDIILVRIRCKRGIVMYKVCIVEDIREQRKILAENIVRIFEEA
                     GKDVEVISFSCGEDLLGANIDNIDIFFLDIDLNKLSGMDIARIIRSKEIKAEIIFTTS
                     LIDYIQDGYKVRAYRYLLKPISYKNLKEAIRSCIKDIAKYKRFIRLNYKNVNYNISIN
                     EILYIEVIRKDLYVYTEEREYLTKNTISNLENELKGLNFFRCHKSYIINLEKIQSLTR
                     NTIYINNNEIPVSKYRVKNLRDRLADILGDIIC"
     gene            12629..13945
                     /locus_tag="JAM15_02955"
     CDS             12629..13945
                     /locus_tag="JAM15_02955"
                     /inference="COORDINATES: protein motif:HMM:NF025854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAT6797235.1"
                     /translation="MLSIVWKIINLISTSIDWIILKYLLDKLDMSKKSETITLLNLIA
                     SIIIIFILNVIQTNENLKLLINIFLAIFFYKYNYQVSLIKSVFASLIFYMVFMGLDTI
                     SSGIIILINQNSDFNVLLHNTYQRLELILLTKALLFIIVYFIKFKNFSLSINKKDTIN
                     IIIPIVANVGSFIVIFFLVFKDQKFNFQESVVIFLISIILMMSNISIIVVISKVIRLN
                     RLEVENSIMKNNINIQYKYYSSLVSYQKKIRHLHHDINNHINTLKSLPNDCEIYEEYV
                     KNLEERVLENQYIYNTGNIVLDAILREKHNKCSVENINLSIDIKLNEELFIKPDDICI
                     IFANIIDNAIEACSKANEGMIKYIKLRATLVNKFYVIKCENSRFNEVKINNLKITTDK
                     KDKFFHGIGLSSVRYSVEKYNGYIKINTPNDKFEILIYIPIGKLSS"
     gene            14064..14210
                     /locus_tag="JAM15_02960"
     CDS             14064..14210
                     /locus_tag="JAM15_02960"
                     /inference="COORDINATES: protein motif:HMM:TIGR04223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HAT6797236.1"
                     /translation="MKNMKKIIIGVLGNLAVCTLFISANTASPWISYQGKEPENIKEF
                     KIKR"
     gene            14240..14830
                     /locus_tag="JAM15_02965"
     CDS             14240..14830
                     /locus_tag="JAM15_02965"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HAT6797237.1"
                     /translation="MIKSLARKATLFLLDNKSIKLNQYELYLYGFETLIALIINILVI
                     LLVSIILSKFIETVLFLLVYCTIRQFTGGYHAENHFKCLLVFLLVYIINIIILKYVYY
                     NNLEWTIILLMFMSCIGIFKIAPMEHREKTLSSIDVASYKKIVRILVSFSFGTILFLF
                     LHNIYNQYILYPASAIVCIYIMLILGIIKEKKLQIV"
     gene            15031..15180
                     /locus_tag="JAM15_02970"
                     /pseudo
     CDS             15031..15180
                     /locus_tag="JAM15_02970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013725896.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            15872..16705
                     /locus_tag="JAM15_02975"
     CDS             15872..16705
                     /locus_tag="JAM15_02975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAT6797238.1"
                     /translation="MVIKKVFNNNVVFARDNSGQEVILMGKGIGFNKFTKDLVEIDKI
                     EKKFIFNNEESLSELHSLLDRIPLKDVELVSEIIQMGREELGDNLNDSILITLSEHIS
                     YMLKRMDEGLVFQSPLQWEIRQIYPNEYNFSKKAVEYLRKKLDKNIPDSEIAFITIHF
                     ANAQLETKDMQETLLLTKIIDNVLDIIKYHYGIEINEYSFDYTRFISHLRCFIKRQLS
                     GENTNVDTSLLDIIKMKYKSDYNCAKKVKNFLEKTYKWKISENELLYLTLHLNRLSNI
                     K"
     gene            16831..18672
                     /locus_tag="JAM15_02980"
     CDS             16831..18672
                     /locus_tag="JAM15_02980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAT6797239.1"
                     /translation="MKFERESEEIIKYIGGKENIISLVHCATRLRFKLKDTSKTNKEE
                     LLKMKDVLSVVNSGGQYQVVIGNKVTDYFETIIKKAVLQGQNTEEQGEKVSIVSKIFE
                     SISGAFSPLIPALAGAGMIKALLTILTTMKWMSDTSSTYAILSAAGNAVFYFLPIFLG
                     ITLAIKLGTNPYVGGVIGAALLDPNFTALIGAKGGANFFGMPVTAIDYSFGVFPIFVA
                     IFIYYYVDKLLKKIILKDLQLFLVPMISLLVMVPLTVILFGPIATNVGDVISNIFMGL
                     FEFNRVIAGAAIGIAMPFLAVLGLHWGFTPITLQNLATMGGDPIEGAAVAAVFAQIGI
                     AIGLFMKVRKSKKNSELKVLAGSTAVTGILAGVTEPIIYGIILRYRRMIPVLAIAGGI
                     GGGICGVFGVTCNAYVFHNIFSMPVYTPFLGYILGIGTALVLGAVLSYFFGLSKEECE
                     EGNEEVAFDEDDGIEEILSPIEGLQIELSEVEDEVFASGTIGNGMAIIPSKGEVVSPV
                     NGTITTIFPTKHAIGITSDKGVEILIHVGLNTTMLDGKYYTTHMNAGDKVKKGDRIVS
                     FDKDKIEGEGYSIVTPIILTNTNDLADVIVKENKHIKIGMPVIKVVY"
     gene            18695..20128
                     /locus_tag="JAM15_02985"
     CDS             18695..20128
                     /locus_tag="JAM15_02985"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013400558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAT6797240.1"
                     /translation="MKSNQEFLWGGAVAAHQVEGGYNKGGKGISIADVMTAGTHTISR
                     KITDGVIEGLNYPNHEAINFYENYKEDIRLFAEMGYKCFRTSIAWTRIFPKGDESTPN
                     EDGLKFYDDLFDELLKYNIEPVITLSHFEMPYHLVKNYGGWRNRKLIDFFVNFCEVVM
                     NRYKDKVKYWMTFNEINNQSITTNPIYAFTNSGIIYEEQEDKEEVMYQAVHYEFVASA
                     KVVKIGHEINPEFKIGCMVAAMPSYPYSCNPEDMIKFVESNREQLMFTDVHVRGHYPR
                     HTLKLWERKNYNLDITEEDKKILKEGIVDFIGCSYYLTTVVTADKTMKTTGNDSAGKA
                     DVVENPYLKTSDWGWNIDPVGLRFYLNQLYDKYELPIFIVENGFGAEDVLKSDNTVDD
                     DYRIEYLASHIREMKNAIEIDGVDVIGYTVWGCIDPVSFTTGEMKKRYGFIYVDKNND
                     GSGTLKRYKKKSFDWYKKVIKFNGEIL"
     gene            21156..22199
                     /locus_tag="JAM15_02990"
     CDS             21156..22199
                     /locus_tag="JAM15_02990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAT6797241.1"
                     /translation="MKRKIAVVLLTVAMLLSLVACSNDNTSKSDKLEDTLVVYTTHGE
                     DMLGAISEEFTKETGVNVEFINLKGELADRVRSEKDNPQADIMFGGDTSTYMQLKEEG
                     LYEKTEPSWNNELDKSYKDSDGYWYGTIKTPVVMFYNTKLLSADKAPKDWSDLTKEEY
                     KDLIVTRDSLSSSMRSTISNLINYYSNTKSEEEAWKYLEDLNKNIKNYYNSGSVMYSA
                     IGKGEATISVAVLSDIIENKEKNNMPLEVVDAESGSVVITDCVAALKNAPHPNAAAKF
                     VDFVGSAKVQAMVANDFNRIPTLDSALKDSPKWMSKEYKAMDVDWSVIGKNQSNWIEK
                     WETDIIDNNKTIK"
     gene            22478..23335
                     /locus_tag="JAM15_02995"
     CDS             22478..23335
                     /locus_tag="JAM15_02995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797242.1"
                     /translation="MELKISDYKLLCNKGSGAFNEDIVGLSPYGAWVLDGATGLNNKN
                     LVSTESDAKWYVSWWNSYLHENMEREDSLKVIIKEGIEEITKEYYKLTDDKEVEAIDI
                     PSCSCSILKFYKDKIEYLLLGDCTLLVNNNESVKILKDETLCELDKKAFDFMKEAKDA
                     TNLTLKERKAEVMPIIIENRLKKNTVGGYWTLEFSKEAVDNCVSGFIDIEYKMKIMMA
                     SDGFSCGYDRYKIFDKNEMMKIAEIKGIDYIYRKVRELEKDDEMAIEFPRFKIYDDSS
                     CVYLEIYKY"
     gene            23354..24346
                     /locus_tag="JAM15_03000"
     CDS             23354..24346
                     /locus_tag="JAM15_03000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6797243.1"
                     /translation="MKNIELKEINHYYGKEKVLHDINISIKEGEFFTLLGPSGCGKTT
                     ILRIIGGFIKPSSGSIYVGDKNITNLEPENRNMGTVFQNYALFPNMTVEENVSYGLKI
                     KKLSKKIIKEKCDNYLELAGMKDFRKKKIDELSGGQQQRVAVARSLATEPTMLLLDEP
                     MSNLDIALRIKMREEIREIQQKTGITTLFITHDQQEALAISDRIAVMDKGKVLQIGVP
                     IEVYKSPLNDFVANFVGTSNCIEKEDYVNFNIEKETKPYIYKRPEEMILLQNTNQSGF
                     VKVKVESKNFLGAILEYTVSNDGKKYQVTELNRLNNSNKLNVGDMAYLGVLQGD"
     gene            24348..26042
                     /locus_tag="JAM15_03005"
     CDS             24348..26042
                     /locus_tag="JAM15_03005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HAT6797244.1"
                     /translation="MIKKINRSKFTSKNVIFIVLYSILFWILIGYIIIPIGNTFVQAF
                     QGKGGYSFEVFKEYFSNTNNLRVVSNTIILGLGSVFVCGIMGISLALYMTFVCDKHKK
                     IIHILLLSPMMIPGVIMVIACIQIYGESGIVTKSIEILLPFIKKPYDFSGLKGILFVV
                     AYTQYVYFYLNVYVALKYVDYSTVEAAKGMGASKLRVFFDVIWPVITPAVITSTIITF
                     ASGISSFSAPNLIGGGFKVLSTQIVRSKANNHMDIASVQVITLLLMGILFMILLQYYG
                     KKYGVVPSLKSQSYKVHNRKKDLFTFVCKVIIEIQIIMIMLPIVTIVYLSFVSTHSIM
                     TTIFPRDFTLENYQMIFQKSRVLQPILNSFKMSLMAVAVGLIITVPVSYLVIKKDTAY
                     NRLAKFIIMLPWSMPASAIAVNLINTFNQKSIFAFNESLIGGFYIVPIAYTIYALPLL
                     FSSNEVAMKSINLGLEESSRSLGAGRIKTFYNVIVPNMMPGIISGAILVFIRTIGEYT
                     MSALLYGVYNRPISISIVTNMQEFKIGVSMAYGVLVIGICYIALGIIFKLDRKRFT"
     gene            26592..27470
                     /locus_tag="JAM15_03010"
     CDS             26592..27470
                     /locus_tag="JAM15_03010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HAT6797245.1"
                     /translation="MLINMKEMLKVAQENQFAVPAFNIGSGQILKAVVQSANEKNAPV
                     ILAIHPNELSFLGDSFVVSCIEEANKSKVPMVIHLDHGENKEQILRAIRCGFTSVMID
                     GSHLPYEENVAISREIVEIAKGLNVSVEGELGTIGTTGTSSEGGTDEIIYTDSKLAKD
                     FVEKTGVDTLAIAIGTAHGIYPKGFKPELKLNLLKEIKEVVDIPLVLHGGSSNPDEEI
                     AQAVKLGVCKINISSDVKSAYYKKCRELLEQTPNLYEPDTIYPPCIKAAREVIEFKMN
                     LFNAIDKLKCFYKNKN"
     gene            27506..29401
                     /locus_tag="JAM15_03015"
     CDS             27506..29401
                     /locus_tag="JAM15_03015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAT6797246.1"
                     /translation="MIGKILRSDCIVLDKQLQTKKDVINYMANHLYHGNYINNKEKFI
                     ADINKREKESSTNMGNLIAIPHAKSSVVNQPVMMYLRTDREITDNDGQKLRSFFMIAV
                     PESGSDEHLKIISKLATYLMEENFLKHLLSAETPYEILSIFNNKAAESGDFSNNQNKG
                     LIVGITGCPTGIAHTFMAKKALEEAGQELGYEVKIETHGAIGVENKLTKEDIKRAEYV
                     IIACDKEVQMSRFIGKKVLQKKVVDAKNVSLAKNLIINAENGMAKEIKPGGKTLEDSK
                     EMLQGSETKGVYKHLMSGVSEMIPFVVIGGIGIAIAFMFGIFASDPTHETYNPIAGFF
                     GQLGGDSAFKLFIPVLAGFIAKSIAGRQGFAPAMIAGFMAVIGGSGFIGGMVAGFATG
                     YIALGVMKITENLPDVLKGVNAVLICPLLIAFTSGAIMFFVVNTPASWLNEALQSWLQ
                     SMSGTNKVLLGAILAGMMASDMGGPINKTASAFGLAMFSSNIFEPSAALMVGGMVPPL
                     AISLAMLIFKNKFTKEERKSSLPTAIMGASFITEGAIPFAAADPLRMIPANIIGSCIG
                     GAICMSLDITLMAPHGGIFVIPFACSAPVAYIACILIGTVITALIIGVAKPTIRSENS
                     EVELLGA"
     gene            29669..31576
                     /locus_tag="JAM15_03020"
     CDS             29669..31576
                     /locus_tag="JAM15_03020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HAT6797247.1"
                     /translation="MLVSRQIEFLKLILNENKYRPIKYFKDKLNVSDKTLQKDLKMIE
                     KYLETFNIKIDIKRGYGILIEDLAKKNIDLINSLNIQSKENKSLSVEQRRMEILKYLL
                     LNSNNITSINQLADKYYVSKTSIVNDFKYIEAWIKEYNLKLNKTLEGTKIIGKEVDIR
                     KSIAKMMDDLLDENYEQHDISELTRLDSATFSALINLFDIDSIIFVETIITELEYNLG
                     YTINQPYYINLITHILICLKRIEEGNQIESQEEREISVDNLDELVYKNVTTLIDKIEN
                     RYRVKITKDEIMYIYIFLVSSGFSSENNSSYNDESDILSESEKVSSIMIENMSQFLNI
                     NLKNDDLLQKSLASHVRPMLNRLRYDIQIKNPLLGEIQERFSDVLGLCMMTINIMTEY
                     DNLKNISIDEVSYLATYFQAAIERNMSSKRVIVVCHTGYGTSQLLAARLKREFPEWTI
                     VDIVPMHQLSKRNLDDVDFVISTVNLDLKDKLHIVVSVLLMESDINNIKNALLSKPKK
                     SMNLDTNLLGMYLEDNIYFNFDVAQMESLIGVNLGSKYESISLGKDLNIYIHKQSKLN
                     KGIMNINNVTRTIDIYLEISNQSFLKNILMEISNLYRQKNYINYIIDCKSKEDIKILF
                     KNNLLEKTNGN"
     gene            31566..32015
                     /locus_tag="JAM15_03025"
     CDS             31566..32015
                     /locus_tag="JAM15_03025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAT6797248.1"
                     /translation="MEIREILTEESIILDLKSTTKEGIIQELVDKLYDTGSITLKSKF
                     IKALKHREKIGSTSIGYQMAMPHGKTKYVKKASIVIGKSKKGVDWPSIDGLPVKVIIM
                     FAMPQSGGNEDMILISKIAYILGGKSISERLLNAHTKKEILDIFYEV"
     gene            32115..33002
                     /locus_tag="JAM15_03030"
     CDS             32115..33002
                     /locus_tag="JAM15_03030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAT6797249.1"
                     /translation="MAIYLEMPKLIHEFPFRSLSNEGEVLTTPHWHKEIEILLITEGV
                     VNLFINDKPMQLKKGEIVIIKGGDIHYILPSPGSERLVFQFDISFFNDLILLNEEKES
                     LINLFSSIKKCSRDWSAKIRKSVFDILIDIYNEDLYKIEGYSYAIKGKMYNLIPILYR
                     QIPREIEENTVEYEINSKEILERLNNIFKYVEKNYKQPIKLEDVSYEVGFSVYYFTKF
                     FKKNTGKTFITFLNEYRLEKAKWILLNNNISIVDLVEEVGFGSTKTFYRVFKEKIGVS
                     PLEFKKRYNSLEKKGGASK"
     gene            33407..34855
                     /locus_tag="JAM15_03035"
     CDS             33407..34855
                     /locus_tag="JAM15_03035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HAT6797250.1"
                     /translation="MKLGKDFLWGGAISANQSEGFYLDGGKGLSQFDKLPLNDKRLKD
                     VCLDEDNILNENNQYYPSHIGIKFCENYKEDIAMLAEIGFKCFRFSISWSRIFPTGEE
                     SEPNEKGLQLYDNIIKELKKYNIEPLITISHFDIPYSLVEKYSGWADRRVVNLYVKYA
                     EILMKRYKDDVKYWIPFNEMNMIMHIPYIGAGLTFIADENQLQKKYQAAHHQLLANAK
                     TIEIGRYINKEFKFGCMLAAGKTYPYTCKPEDVFATLEHERHNLFFSDVQVRGVYPSF
                     MNYYLKSNQIKLIIKEEDLSTLKDNTVDFVSFSYYSSACSSARAEGLEKSKANGPETI
                     KNPYLPKSNSVWQNDPVGLRITMNQLYERYQLPLFIVENGLGTQDIVNEDGKIIDDYR
                     IDYMKEHIKNMILGVNEDGIELIGYLMWGCIDVTSVSEGKMTKRYGIIHVDSDDYGRG
                     SFKRTKKQSAFWYKKVIETDGEILFNDMETHA"
     gene            34881..37271
                     /locus_tag="JAM15_03040"
     CDS             34881..37271
                     /locus_tag="JAM15_03040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HAT6797251.1"
                     /translation="MSLIFTTKDQLIEQGFSKDTIKSNETLFTLANGHLGVRGNIEES
                     DFNNEYVDNMGTYVNGFYEESPITYGESAYGYAKQNQTICKLPNAHIVNFSIEGDCFD
                     LSKGITSEHTRILDLNEGILKRSFIWENSRGRKVKVSIERLVSQDIEELMMISYTITP
                     LNFNGKIKFKNKMENSMEKFNCEKVDDPRVASINKKQFKINVKKYNNKYFMNLVTERS
                     RLGLWCGFDSYITCGNITNETYNVSDECIEREIEVYAKKDERLNLEIVVGYSRVYSDL
                     NLNEERLKSLECLESLKCLESEAHLKSLELVLREACNIGFDKVKNIQRKKMNEFWTTS
                     DVEIEGDKTLQLGIKTNLFHIYQSAGRDGKTNISAKGLTGDGYEGHYFWDTEMYILPF
                     FIYTQPSIARALLDYRYSILDASRERARELGINKGCLYSWRTINGNECSAYYPAGTAQ
                     FHINADIAYGIRMYFEATNDEEFMMQNGLEILIETARFWVEFGDYIELKNNKFCINGV
                     TGPDEYTAIVNNNYYTNLMAKYNLIYAVQMVDKFKHNLFSNEVFRKVKLQEYEVKDWI
                     NAAQNMYLPYDEEKKISKQDDSFLEKSVWDFKNTPKEKYPLLLHYHPLTIYRYQVNKQ
                     ADTVLSALLFPDEFSLEQKKRDFEYYEKITTHDSSLSRSIFGMMASEIGNHEKAYSYF
                     MDTALMDINNLQKNTSDGIHAANMGGTWMSLVYGFAGMKIKKDKLSFEPRIPKHWKNI
                     KFNILFRDNLVSVNIEEYKSYYKLIKGKNISILHDNKEIKLSKNIIEVNNCFKGSN"
     gene            37273..37944
                     /gene="pgmB"
                     /locus_tag="JAM15_03045"
     CDS             37273..37944
                     /gene="pgmB"
                     /locus_tag="JAM15_03045"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HAT6797252.1"
                     /translation="MKAVLFDLDGVITDTAKYHFEAWHEIAKSLDIEIDETFNEKLKG
                     ISREESLDKILLSANKVDSYTKEEKLKVCEEKNNIYIKLINSLTYKDILPGINELIKE
                     LKKNNVKLGIASASKNAPRILESLGIKDEFDCIVNPSLLERGKPYPDIFIEGSKMLNL
                     KQYDCVGIEDSYSGIKAINAANMTSIGVGKKEVLGKCDHIVEDTSLLNYNTLLQAWSK
                     KINLD"
     gene            37983..39383
                     /locus_tag="JAM15_03050"
     CDS             37983..39383
                     /locus_tag="JAM15_03050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAT6797253.1"
                     /translation="MKNKYEEVAQLIIDGLGGKDNIIDLTHCMTRLRFILKDEKKVNA
                     DKLKSIDKVVGVNSTSTQYQVIIGNEVGVVFNAIINKGINTTGDIKSDIKNENKKNSI
                     LNNIIDTITGCMTPMIPALTASGMIKVILSLCTTFNWLSSNSSTYRVLDIIGDVAFYF
                     MPIILAINAAKKFNVNTSIAVIVVGVFLHPNFSAWVSSGDPISFIGVPIQGVIYAASV
                     IPALLTVWMMSYIEKFIDKLIPSMLKTILNPTLVLLISAPIALIVIGPIGNFLGEGLA
                     SIINLLQGKLGFIMVCLLAAAMPFIVMTGMHHALTPIFISAFATTGQESLILISQVCA
                     NLAQGGATLAVALRSKDSKMKQLASAAWISAIMGITEPALYGVTLKLKKPAMLASIGA
                     GIAGLFAGITHVTLYVPQNSIMAVLGLSGEKGISNIVNGLIVIFIALVAPFIMTYVFG
                     VEKNVKESTDNVVEEV"
     gene            39700..40542
                     /locus_tag="JAM15_03055"
     CDS             39700..40542
                     /locus_tag="JAM15_03055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAT6797254.1"
                     /translation="MIINKILNNNVVITLDDNDEEVIVMGKGIGYQKSKGNLIDKTKV
                     NKVFRISNKEISNKLQELLNNIPIEHMKLSSEIIEYAQIKLNKKLNESIYISLSDHTY
                     SAIQRMKEGINVKNAILWEIKRFYKEEFEIGMKALDIIENKTGIKLPEDEAGFIAFHI
                     VNAQLSEGHTLASDITKLIQEVLSIVRYHFRIEFHEESVFYYRFIMHLKFFAQRLLLD
                     SAHEGETDKELLSIIKSKYNKEFECVVKIKNFIKKQYNYILTDDELIYLTIHLAKVVK
                     DSNM"
     gene            40687..42615
                     /locus_tag="JAM15_03060"
     CDS             40687..42615
                     /locus_tag="JAM15_03060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAT6797255.1"
                     /translation="MGKYKQLAQEIVNNVGGKENISGLVHCITRLRFTLKDESIANDN
                     VLKNMEGIVTVMKSGGQYQVVIGNHVEAVYKDVVEIIGLDDSSTSSETKKSGNILDKG
                     IDIISGIFQPVLGIMAACGMLKGFNALFVAMGLYSDVSGGYMVINAAGDALFTFLPLF
                     LGYTSAKKFGLKPMLGLALGAAVCYPAIQGSSISAGADVMYTLFKGTMFASPVYIDFF
                     GLPIVSIDYTGTVVPIIFIVYFASRCEKLFNKFVPDLVKFFFVPMLTLLITVPVALIV
                     IGPIATFGSTLISQIVISIRDFSPLLAGAIVGFTWQILVIFGMHWGFIPVYINNVMTL
                     GYDNVMMPFFACTFASSAVVLAIFFKTKDKKLKEMTIPNFISGIFGVTEPAIYGILLP
                     LKKPFIISCIASGIGGAFYGFFNLRKFITGGMGIFELPAMIEPDGGMGNLIVALSGIA
                     ISMVVAFVLTMILYKDEKVEESKKVRNKGKEEIKEVKSTKLEREIVASPIKGEVLKLS
                     DIEDAAFASGVLGQGVAIIPSDGKVVAPVDGVVTTLFPSLHAIGILSDTGVEVLIHIG
                     LNTIQLEGRGFEACIKQGDRITKGQTILNFDVDAIKELGYSTVTPIVITNSSQFLDVV
                     ETESKNIELEDNLITVLF"
     gene            42676..44103
                     /gene="ascB"
                     /locus_tag="JAM15_03065"
     CDS             42676..44103
                     /gene="ascB"
                     /locus_tag="JAM15_03065"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAT6797256.1"
                     /translation="MSFKNDFLWGGATAANQCEGGYNEDERGLANVDVCPTGKDRTAV
                     ITGKLKMFDFDDEHYYPAKTGIDMYHNYKEDIKLFAEMGFKVYRMSIAWSRIFPKGDE
                     ETPNEKGLQFYENIFKECKKYKIEPLVTITHFDCPMHLVKKYGAWRNRKMIGFYEKLC
                     NVIFRRYKGLVKYWLTFNEINMILHAPFMGAGICFEEGEDVEKIKYQAAHHELVASAI
                     ATKIAHEVDSNNLVGCMFAAGSVYPYSCNPNDVWEATKLDRENYFFVDVQSKGKYPNY
                     ALKYMEQKGITPEMEPGDIELLNKYTVDFISFSYYNSRCVRTDENADDMAEGNIFTSA
                     KNPYLSYSQWGWPIDPLGLRITLNHVYDRYEKPLFIVENGLGAKDIADENGYVEDDYR
                     IDYLREHIKAMHDAVSIDGVDLLGYTTWAPIDLVSAGTGEMEKRYGFIYVDRDNSGNG
                     SLRRMKKKSFEWYKKVIASNGEDLY"
     gene            44508..45290
                     /locus_tag="JAM15_03070"
     CDS             44508..45290
                     /locus_tag="JAM15_03070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HAT6797257.1"
                     /translation="MNMKYQHIIEVDKELCIGCGLCKNDCPVNNIIIENKKSVIKKQD
                     CLMCGHCAAICPTKAITLTGFDEPPIELTNKSKLDSDELLMAIKSRRSIRKFKDKEVS
                     SEIVKQIIEAGRYTPSAKNSQDVSYIVLDNKKSIYENEAVKFFRKIKPIANIAIKYSK
                     EVEIDDNFFFKHAPIAIMIITKDKISGSLAASNMALMAESYGLGVLFSGYFSDVANNS
                     PKLKKLLGLKRSNHVLTTLVIGYPDVKYRRTAQKEVATVRYL"
     gene            45306..45671
                     /locus_tag="JAM15_03075"
     CDS             45306..45671
                     /locus_tag="JAM15_03075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HAT6797258.1"
                     /translation="MEKECQQRMQEITSKFKECRKAISAMGDETRQLILIALLESDFN
                     GIRVGEITKKTHLSRPAVSHHLKILKEAEIVNLRREGTKNYYYLDSKKSQWKSLTELI
                     NLIFVGIQHISENDIRKGD"
     gene            complement(45837..46586)
                     /locus_tag="JAM15_03080"
     CDS             complement(45837..46586)
                     /locus_tag="JAM15_03080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HAT6797259.1"
                     /translation="MILYFSGTGNSRYVARKIAQELNDELISLNQLIKEEKTDELISA
                     DKPFIFVCPTYAWRLPIVVTDFIKETKFLGDNRVYFVMTCGGDTAKSINYIQKLCKYK
                     EWQLKGMAEIKMPENYIALFSTTDKETSKQMIKEADKQIYRIISDIRNENEFETITPS
                     GLGGTIKSGIINTVFYKTIISAKGFHYTDKCIGCGKCVELCPLNNINLKNKKPVWKNS
                     CTHCMACICGCPTEAIEYKNKTQNRERYYLE"
     gene            complement(47031..47588)
                     /locus_tag="JAM15_03085"
     CDS             complement(47031..47588)
                     /locus_tag="JAM15_03085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAT6797260.1"
                     /translation="MRTLKYAILGLLNRNPMTGYDIVKEFNFQLAEFWNAKHSQIYPE
                     LKKLVNEKLIVYDIKISGDVLEKKLYTITEKGKDEFLKWLEKDEPMERTPKDIFRLRM
                     YFSNNLDIDTRLILLEHQLLQHQERITFLYSQMERYSEVPPLDSNDFGDYIVLDGAII
                     REQGAIKWLTNCINHHKNLDNTTLK"
     gene            47840..49138
                     /locus_tag="JAM15_03090"
     CDS             47840..49138
                     /locus_tag="JAM15_03090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HAT6797261.1"
                     /translation="MNLTQKRWIILIASCFINLCIGSIYAWSVFASPMAEHLNSLAGT
                     TFTAASLAIVFTVTNSVGPITMITGGMINDKFGPKKVVFVGGLIFGIGMILAGFSKGL
                     PMLILSYGIITGLGVGMVYGCTISNSIKFFPDKSGLVGGITTAAYGFSSVIMPPVANW
                     IINKYGVTSAFKSIGLVFLIIVCVSSFFIKKCPADFTPEGWVPPEKKGKVRVVINKNW
                     KEMLSTPIFYLMIIILTCGAFYGLMCVSLASSLATNMIGMTSSDSAIVVSILALFNTL
                     GRIVAGYISDKIGRINTLSGALVISIFGLLCLLFSREGDVATFYIGIIIIGICFGSFM
                     GIFPGFTVDKFGPKNNSVNYGIMFIGFAFAGYIGPAVMKNVYSVDGNYQRAFIIAIII
                     ALIGFILTFLYKYINKIQNLKIENLIKGDIKNGKKISKSM"
     gene            49110..51059
                     /locus_tag="JAM15_03095"
     CDS             49110..51059
                     /locus_tag="JAM15_03095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015394831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAT6797262.1"
                     /translation="MERKYPNLCKPIKIGNVTFKNRMFSAPMGGTDITADCTIGSKST
                     AFYELRAKGGAGAVTISECMVHPETDGSHAYHLDLKIVDSLASFTYTADAIRRHGAIP
                     SVELSHSGQYSGTYLVDKDKKRGLSQWGVSPSVRPDGLEIKELTEEIIAEIVESYGNV
                     AALAKRAGFEMIMIHGGHGWLINQFLSPYFNKRTDKYGGSLENRVRFAKEVLDSVRKA
                     VGPGFPIEFRMSGSELFEGGYDLDYGTEIAKLLESRVDLLHVSAGTYQRGFAVTHPSM
                     FLEHGCNVYLAEEIKKHVNIPVATIGALNDPEMMEEIIASGKADVIYMARALLADHEL
                     PRKVMSNQDEKIVKCLRCFTCMAERATTSTRRCTVNPLIGRELDGTEVVSVLKPKKVL
                     IAGGGPGGLQAAITAVKRGHKVILCEKTNELGGILKGEQALPFKYEMYELGNTFGKIA
                     KDLGVEVRLNTTVTKEYVENENVDALIIAVGSEPLVPPIEGLDGENVVIVNDYYVEKE
                     KVTDEVIVLGGGLAGCEAAIHLAQEGKTVHLVEMRAELAPDANIRHRPILLEEIERQG
                     IYVYTEHKGLSVTTEGVVCMNKSGNKINIPGTSVICALGQKPRREVVDTLLDSAPYVA
                     QIGDCVRASTITNAVYQGHHAALDI"
     gene            51496..51612
                     /locus_tag="JAM15_03100"
                     /pseudo
     CDS             51496..51612
                     /locus_tag="JAM15_03100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861830.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            51880..52254
                     /locus_tag="JAM15_03105"
     CDS             51880..52254
                     /locus_tag="JAM15_03105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004844823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2500 domain-containing protein"
                     /protein_id="HAT6797263.1"
                     /translation="MFNLIEMLFPIMFILIFIIIVFTFVKGIATWFKNNNSPRLTVSA
                     RIVAKRQNTTHNNQPNAGDISGAHGFHTISSTSYYVTFQVDSGDRIELSVSGSEYGVL
                     AEGDKGQLTFQGTRYLTFDREN"
     gene            52270..52917
                     /locus_tag="JAM15_03110"
     CDS             52270..52917
                     /locus_tag="JAM15_03110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004851532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797264.1"
                     /translation="MNKFLSQIRRIENEISITRKIINTIFILCFGIVLGTFAKFLDTT
                     ASNTLPFIFEYLDISNFFGRFAIWLLIALYIAIYSHSSIRASLNVLVFFIGMVSSYYL
                     YSYFVAGFFPKNYAMIWLGFTVISPLLAFICWYAKGKSKISFILSVIIIAILFNFTFI
                     YGWIYFDVYSILEVIVFGCALIALKRNTFRETTYMILSAVVIAVILNMLVPFHFG"
     gene            53297..54376
                     /locus_tag="JAM15_03115"
                     /pseudo
     CDS             53297..54376
                     /locus_tag="JAM15_03115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005342988.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            complement(54868..55106)
                     /locus_tag="JAM15_03120"
                     /pseudo
     CDS             complement(54868..55106)
                     /locus_tag="JAM15_03120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009321353.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            55198..55411
                     /locus_tag="JAM15_03125"
                     /pseudo
     CDS             55198..55411
                     /locus_tag="JAM15_03125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008394616.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA wybutosine-synthesizing protein 3-like
                     protein"
     gene            55523..57136
                     /locus_tag="JAM15_03130"
     CDS             55523..57136
                     /locus_tag="JAM15_03130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4368 domain-containing protein"
                     /protein_id="HAT6797265.1"
                     /translation="MKQQIYNTALYLRLSRDDELQGESSSITTQRSMLRLYAKEHHLN
                     VIDEYIDDGWSGTNFERPSFQRMIEDIEAGKINCVVTKDLSRLGRNYIMTGQYTELYF
                     PSHNVRYIAIDDGVDSEKGESEIAPFKNIINEWVARDTSRKVKSAFKTKFAEGAHYGA
                     YAPLGYKKHPDIKGKLLVDDETKWIVEKIFSLAYQGYGSAKITKVLREEKVPTASWLN
                     FTRYGTFAHIFEGKPESKRYEWTIAHVKAILKSEVYIGNSVHNMQSTVSFKSKKKVRK
                     PESEWFRVENTHEPIIDKEVFYRVQEQIKSRRRQTKEKATPIFAGLVKCADCGWSMRF
                     ATNTANKTPYSYYACSYYGQFGKGTCSMHYIRYDVLYQAVLKRLQYWAKAVQQDEEKV
                     LNKIQKAGNAERIREKKKKASAFKKAENRQNEIDRLFAKMYEDRACEKITERNFVMLS
                     SKYQKEQIELEQQITNLREELSKMEQDMIGAEKWIELIKEYSVPKELTAPLLNAMIEK
                     ILIHEAITNEDNERIQEIEIYYRFIGKVD"
     gene            57165..57488
                     /locus_tag="JAM15_03135"
                     /pseudo
     CDS             57165..57488
                     /locus_tag="JAM15_03135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861830.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
     gene            57520..58707
                     /locus_tag="JAM15_03140"
     CDS             57520..58707
                     /locus_tag="JAM15_03140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HAT6797266.1"
                     /translation="MSKIVFFSILAYGHTNPTIEVVRELVDRGNEALYYSFNEFKDKI
                     EGAGAKFICCDKYLPELLPGDEKKIGKDFPGLIEMIVDTTISLDEKVCRELKDFNPDC
                     IVSDSLSFWGKLFAQKLNIPYVCSTTTFAFNKHTAKLMKQNFIEIIRMIFGVRRINKK
                     IKLLQRKGYEVKNFISIVSNDNDTDTIVYTSKEFQPMVETFSSKYSFVGPSVSKLIIK
                     PKERKRKLIYISLGTINNKNVSFYKNCINAFKDSDVDVIMSVGRSTDIKSLGNIPNNF
                     EVKNSVEQIAILQKTDVFITHSGMNSVNESLYYGVPMVLFPQHSEQRMVAKRVVHLGA
                     GIMLKEDKSESIKKAVFQVINDNEYKENATKLSKSFYNAGGSKKAADVILQIICNSRQ
                     VDI"
     gene            58899..59303
                     /locus_tag="JAM15_03145"
     CDS             58899..59303
                     /locus_tag="JAM15_03145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="HAT6797267.1"
                     /translation="MKKYKVIFIVLIIGIISVTGFVVYKNCIKPWKDAETYIDKYMVK
                     QDISKDNIKSITKEKAKKASYEGILYKVYYKDDPRYEYQYFYSDNYHALYVNKVMLQI
                     YDVENNNKLLRSNEELKSVKYPPIYLKYKPDK"
     gene            59975..60835
                     /locus_tag="JAM15_03150"
     CDS             59975..60835
                     /locus_tag="JAM15_03150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAT6797268.1"
                     /translation="MKIIQILNNNVALVKRGKNEIIVFVKGIGFKKRVGQVINENEIE
                     RTYILDSYDMLEHFSYLLQNSDSNNIVLINEIIEYGEKALNIKSSDYLSLTLLDHLEF
                     LLKRCEKNQFIKSPLVWNVKRFYPKHFEIGMHALKLIDDSKGINLPDDEAVSIALHFV
                     NMEVNKESHDSTIVELRTLADIVSIIKYHFNVELDETSTNYMRFTTHLQYFIQRIMSD
                     EASIDEDNSIDLYKQVSQLYPKSFGSVQKIRKYIKSQFNVDISISEETYLMLHINRVT
                     QRLEAKSDEI"
     gene            60825..62696
                     /locus_tag="JAM15_03155"
     CDS             60825..62696
                     /locus_tag="JAM15_03155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAT6797269.1"
                     /translation="MKYKDLNENIIKLIGGKENIKSVAHCVTRLRLTLNDRSIAQTEE
                     IKKLKGVIDVVSNDVAYQIIIGTHVVDVYNEFMSMIGLSSSESSIKSERKKGIRGIKG
                     IFNSIFVVVSETMTSVIEVLLAAGILASILALLNMSGILQSDSPTYQILDTLRSATFH
                     FLPVLIAIASAKRLNVNPYIAVVLAVTLLSSSIDGVEGLSLFGINLQDTTYANSFIPI
                     LLGVWAMGIIIEGLKKILPKALHYFLVPVLSLIITLSVTLTVFGPIGMWIGDGLNYAC
                     MFLIDTLGNWSVVALYAALQPLLIVFGAANFTMPISLNSVTTLGYDPIFMGAATISDI
                     AVCGAMFGYFLKTRNKEQKQLFGTVSFSALMGVTEPSVFGVFMKYRRPFVAVMIGGGI
                     GGLIAGLAQVKTYGMVWGLAALPTYLVGGEASNFTFMIISVVVSFVAATAASYLLGIP
                     SDEKEEVKGDNEKELELIINENNSRTISIGNVAKGQVIALGEVNDKAFSSGALGKGVG
                     VIPSESKSTVISPVDGTITIVFPTKHAYGIVTDEGLEILIHIGIDTVNLDGKFFESLV
                     TQNQRVKKGDALAVFESDKIIEEGFDSTIITVVTNTSDYLDVISSNDESEELLTVIV"
     gene            62716..64170
                     /locus_tag="JAM15_03160"
     CDS             62716..64170
                     /locus_tag="JAM15_03160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HAT6797270.1"
                     /translation="MNIKDTFFWGGSIAAHQCEGSWDSDNKGPAIMDFVTKGSYETPR
                     VITDKIEEKLDYPSHNGIDFYNRYKEDIALFKEMGFSALRISIDWSRIFPNGDDENPN
                     ELGIKYYEGLIDTLIENNIEPIVTLYHFELPMNLVHKYGSWNNRKLIDLYLKYSETVI
                     RRFDDKVKYWITFNEMNHIDPQTEHSDIFTYMIAGIKYSEIENKIQTLANVGYNMTLA
                     GVKVAKLAREINPNNKVGCVFGLNPIYPYNCNPSNVLNAFLDNDRDYYQIDAMCNGKF
                     PQYKLKEYEKNNITIEVTDEDKKAFKEGKLDFIGLNYYFSSVSTPKENLSGDKSLFGG
                     IQNPYLEQSKWGWAIDPIGLRFTLNYIYRKYQLPILITENGLGAYDKIEEDGTINDDY
                     RIEYLSKHLSQMKSAIEEDNVECFGYLMWGPIDLVSATTGQMSKRYGFIYVDLDDEGK
                     GSFKRYKKKSFDWYKEVIKSNGEVLDFSTDIVVG"
     gene            65221..66429
                     /locus_tag="JAM15_03165"
     CDS             65221..66429
                     /locus_tag="JAM15_03165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797271.1"
                     /translation="MENFWNPLTCFTVCVMIYAFSEFLSKKTKGAISTLLFVCIIFLL
                     GFWTNVLPKDITGASGILAAMSNFGIALLITNLGTLINLEDLCHEWKTVVIALVGIVG
                     IGVGCLTVGSMLFGREYALIAAPPIAGSTVAGIIVTTVAEAANRPELAAFVILVLSFQ
                     KFFGIPITTYCINKELKFKRDNGDFLKDESKSNFRLPSMRIFKEDLGKKSSTLVYLAK
                     LSFVAMIGNFVGLATLIPGFTPANYYLNPNIACLLVGLIFTRIGFLEKGILDKSQSNG
                     IIMFGCMLMLPGGLAKVTPTALFGMIVPTIGILVVGSVFIILFTAIVGKLLGYSPRMS
                     AAIGVTCMLAYPATQIISNEGIDAMEGTEEEKQRATDYLLPKMIIGGFVTVTIASVAF
                     ASIIGPIIFG"
     gene            66460..67839
                     /locus_tag="JAM15_03170"
     CDS             66460..67839
                     /locus_tag="JAM15_03170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HAT6797272.1"
                     /translation="MIGSISINEIDKKRFKLDDLSKKIWENPEKAFKEFKACENTANF
                     LRSEGFDVEVGVGGLATAIRASFGSGKPVIGFMGEFDALPGLNQKVSTKQEAFELGAY
                     GHGCGHNLLCTAHVGAVVGLKREMLENNLSGTIVFYACPGEEQLTGKGFMARGGAFEG
                     LDLAINFHPNKISEATIGTSTAVNSVKFHFKGKTAHAGSDPQNGRSALDAVELTNVGA
                     NYLREHVTSDVRIHYTITDGGVAPNIVPDKASVWYYTRALSREAVESTYERLVKVAKG
                     AAMMTETEVEVEFLGGCYNTLNNHVLANLVSECMNEIKQEPWTREELDFAAELDRQSP
                     QQYKAMISKYNLPEGTHLYYGGGNVTNFNSYGSTDIGDVMHIVPTAYFFTGCTNLGAP
                     GHSWQFTSCAGSSIGEKGMIYASKIMAMFGAKILNNPEIAKKAKEEFDKSMNGKTYKC
                     PIPDDIPTP"
     gene            67945..69135
                     /locus_tag="JAM15_03175"
     CDS             67945..69135
                     /locus_tag="JAM15_03175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HAT6797273.1"
                     /translation="MKNFFKEAQSIEGEIIRWRRYLHENPEIGCNLPKTVTFVTSTLE
                     KMGYSPKLTSNNGIVAVLDSENGGKTLLLRADMDALPIMEETDLPFKSKNKDASHSCG
                     HDNHTAMLLGAAKILMDNKHLLKGRVKFVFEPDEESTRGAKSMIDDGILENPQVDAAM
                     AFHSMVGKFLNTGQVAYSRGPAMASADIFEITVEGKATHGASPEFGVDPINIMSHIQI
                     ALNTILSREKPQKEPVVLTIGMFNAGNVPNAIPNKASMSGTLRTFDQFVREKLKNRII
                     EISTGIAKSFGGNAKVEFKMGTPAVINDLDVGDEIVSYVKEIIGNENVIDFPSAMGSE
                     DFSEILLRVPGVFLWIGMGSISQGYNFGMHNPKAIFNEEGLVYGSALFAHCAVKWLEN
                     NFSR"
     gene            complement(69263..70327)
                     /locus_tag="JAM15_03180"
     CDS             complement(69263..70327)
                     /locus_tag="JAM15_03180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797274.1"
                     /translation="MFLKLIFKYNTLDFSRAYFDLTDWADNPKDISYYLSNGTFGDLM
                     DSIDENASKMSLSDIAKLEKKIAKKHINLWNEGKIDFSTTRFSSIVPMLQNAGVNFHF
                     IYPDIDLLKNTFNNLIKDIHLHRMKGNQPSVIYITVKDTNYDDSTLDQVYKILNSIKK
                     DKLTDFIIEKNSNSFKIFTKCETIKSLTKNFTACYIKESIENSTNIKVCVGYGIGNDI
                     KQAMSSAISANKESKINHLNYSFLVNENYETIGPLLCDKLLTVSNKVTPHINTIAKSS
                     KLSTLTIQKIISVTEILQRDEVTPKELSSCLNVTVRTANRFLSSLLKSGNATILYEKQ
                     NSTKGRPERVYKLFISENKY"
BASE COUNT        27638 a         7448 c        12392 g        22966 t
ORIGIN      
        1 ataattgctt taagataaga agaagagtat tataaatgat aaaaattagt gaacatacag
       61 ttaattaata aataatagat aaaaatttaa agtttaaatg taaagaggat gtatagtttt
      121 atgaaatcta ataagacact gttacaaccg ctatgtaagg aaatcatatt agaattttct
      181 aagaaaacag ttaagaattt ggaagtaagt atgggttatt tatatacttc tgaaacatat
      241 aaacttataa gtgaggttgt atcagatatg tcttgtaagg gtaatttatt caggttcatc
      301 aactgtcata actctacaga gggtataaga tatgcattgt aagggtcatg tatgcttggt
      361 tcaagaatta atattataaa acggattaat gtaacataaa gtatatccat gataaacatt
      421 taaaaaacta gataataagg atacaagata atataaaatt aatttgtatc cttattttga
      481 ttttgtaatc aactatatga tgggagtctg aaaatattta tgtgtattct ttaaataaaa
      541 atttattttt taagttacga ttatatgttt taattaaact aaattagctg tgatattaaa
      601 atatatagaa ataatatgat aatatttagt aattttagtt ttgtagtgag caaaaaaatt
      661 atataagtaa ttgtaaatta gttatgtcaa agattacaac tgtatttttg attatagcaa
      721 aaaatactat ttagggatca ctgcaaatta ttcattttaa taatactcta agtattggaa
      781 ttactgtagt tttattttag gtttaaatta tactaagtta gtgcaaataa atcaaatata
      841 tcagaaagta tatataaaat taattatgta taagctatag tgctataagt gcaagtaata
      901 tctaactatt aattaaaaaa tttaattgag agtttaattt atattgttga attgataaaa
      961 attttgaaaa aaaattatac caccattaca aaaataaaca atgaaaaata agtaaaaaaa
     1021 tcagtctaat atcatgacta aatatctata tacctacatt tacaaaaacc agtaaaacaa
     1081 tcaaataaac acttatatac tattcttcac cattgaaatc cacgaatacc catatcttct
     1141 tagatatggg tattcgtgga tttatcaaaa attataacca cataaaagta tttagtttaa
     1201 gttttgaaat ttaaagtttt gaattatgta gtattaaaag tattagtaga aaaagtaatt
     1261 atactataaa atatccactt gtaccttcat atgttctaga taggatattt tattgaataa
     1321 tgtgatttga gatgataaat tgtagataaa gataaataaa gagttgaata taaagaattt
     1381 aaatacttaa aagattaatt ttaaaagtat tataaaaatt ataattgtta ggggtagttt
     1441 gttatgttga atactgataa tactatagaa cttgattaca aaaacaagat tataaagcat
     1501 aaaaataata tgcattttat atacgataaa atatcaaaaa gaaagatatt tgtaagtgat
     1561 gaagttttaa attatatagt aagcgcagaa aagttaaaat tagatgaatc tagttttata
     1621 aattgttttg aaaataaaga tgacaaaatc tatattagag agttaatggt gatgttaaaa
     1681 aaagtaggtt ttattaagaa tgagaattac aatattgaac ttagtaaaat aaacaatctt
     1741 aactttagat cagttcatct tttactaaca aatagatgca atttaaaatg taaacattgc
     1801 tcaagtaatt gtgaaccaga tggagaagat acattgggaa ctgatgaaat taaaaatata
     1861 atattaaatt taaaagaaac taatcctaaa aggattgttt tttctggcgg agagccgctt
     1921 ttaagacatg attttgaaga gataattaga tatgcaaaga cattacttaa aaatactaaa
     1981 ttttcacttt ctacaaatgg gacgttaata aatgaaaata atgttgtaat gattaaagaa
     2041 ttatttaatt gtgttgatat aagtgttgat ggaattgatg aagatagttg ttctaaagta
     2101 agaggtaatg gtgtttttaa taaggttata aagagtgtat atttattgaa aaagaatggt
     2161 gttaatgata tttctctttc tatggttttt ggagtgaaca atactaatat gaaagatgaa
     2221 tttatagagt tgaaccaaaa actagggaca actccaatcg ttagagcatt tattccaaag
     2281 ggaagaggtt atcaaaataa agagttattt aataatggag atgtgaaatt tcctatgtta
     2341 attgcaaata tatataatga taaaactaaa acaaatagca caagaattaa tacctgtgca
     2401 tgtgatgcat ttgaaaatag tttatacata gatgcaaatg gagattgtta cccttgtcca
     2461 tctttaaatt tagatgagta taagataata aatctagcta aagaaaatat taaaattgaa
     2521 tatgttaaaa atagaatggg agtattaaaa agagaatttt tgaatgtttt ggattataaa
     2581 ggaacaaaat gtgaaatttg tgatataaat ttattttgtt ggaattgccc agctgatttt
     2641 ataaatgcaa aaaaaaataa tgaaattgac ttctggtgcg atcttacaaa ggaaaattta
     2701 gaagctattg tatgggggta aataaagtat aatgaatttt actataattg ttacatctaa
     2761 atgtaactta agatgtgatt actgctacga agaaaataaa aaatatcaag atatgtcagt
     2821 tgaagtatgc gataaaacta tagattttat aatcaaatct attcgtgcta gaaaaaacat
     2881 aaatgaatca cataaagttg tatttcatgg aggagaaccc ttactaaaat ttgatttaat
     2941 aaggcatata aaagagagat tagataatga gttaaaatat aaatataaaa ttagttatat
     3001 gatgacaaca aatgggacag taataagtca agaaattatc aattatataa aagaaaataa
     3061 catagcactt tcagtaagtg ttgatggaac taaatgtaca catgataaat ataggaggtt
     3121 tgaaagtgga aaaggttcct atgatatcgt gtacaagaat gtagctaaac taatacagaa
     3181 tgaaataaat attagatgta gattaacata tagatcttta actgtttcag aattatataa
     3241 aggaatttta gaattatcaa gtttagggat aaagaatttt gtaccagttg cagattttta
     3301 tgatactaca tggactaaag aagatattga tgttttagaa tcagaaatag ataaaatgat
     3361 ttgtgataat aagtataaag acctgagagt atcaatgata aatcaagaga ggctatgtga
     3421 gaaacaatct gattgttttg gaggaatagt ttcttttact atatctgaag atggggggat
     3481 atacccttgt acctttgtaa ttggaaatga aaaattccga ataggaactg tatataatga
     3541 tgactgtata gataaagaat attcattaga gctattttat gagaggtttg aagaaagtga
     3601 accttgtaaa acttgtagtg ctaaagagta ctgtatgggt aataaatgta aattaattaa
     3661 ttatatggca aatgggaaat attatgaacc atcaataatt aactgtaatc ttatgagtgt
     3721 aaatttaaga acatataata agttacttaa ggggggggaa ttaggtgcat tataataaat
     3781 attttattaa agatatagct caaatttcag aagaaaagca tattgcctat ataggaaata
     3841 agatgacagg tgattggatt aaaataccta aaatatgtat ggatacgata aattattctt
     3901 atgagaataa gatattagtt ggagacacaa ttaaatttta tgaagatgaa gatgataaaa
     3961 tatattataa aaaaatacta aaaaatcttg ataatatgga tttgttatca acttgttata
     4021 tagaaaaagc agttttaaat agattagaaa aagtaacatt tgctttgaca gaacaatgta
     4081 atttaaaatg caatttttgt agtatggatt cccatataga taaaaacgaa gaaattgact
     4141 atgatacagt tatcagaata attcgcaata ttatgaaatt aaagccgaaa aaattaattc
     4201 taacaggtgg agagcctcta atgagaaggg attttttaga tattcttaag tatataaaag
     4261 ataattatga aactaaggta cagcttatga caaatgcaac attgatagat gaaagcatag
     4321 tagataagct tactagtaac ctttatgcaa tagatataag tatagatgga tacgataaag
     4381 aaagttgtga tagtgtaaga gggaaaggaa cttttgacaa aattaatcat agtatagatt
     4441 tattaaaaaa gaaaaaattt agaaatatta gtctctccat ggtacttgga gaacataatt
     4501 ataatactgt cgataagttt aataagtttt gtgaagataa agaacttaaa gctgtaagta
     4561 gatactttat taggatggga agaggagagt ataataaagt ttacttaagt aatgaaaaag
     4621 atattatgtt tataccaaac attgattata gaccttatct aagatgtcat acatgtaagc
     4681 ctggaataac tcaaatttat attgattata aaggagatgt ttatccctgt tcattattaa
     4741 gagatagtaa atataagatg atagatgcaa ttaaaataga tagttctttt gtttcaaaca
     4801 tctttaataa agaattaaaa gtatataaag agatagagaa actaagtact ttaaattatt
     4861 ttaaatgtaa agactgcaaa aataaatttt tctgtaataa ttgtttatca attatggata
     4921 ctttagttaa tgatgatgat ttatttactc ataattgtaa taaaattaaa gaaataatta
     4981 acatttagat aattaaaagt tataactttt taattataaa ttatattaca agatatttat
     5041 taagaaattt atgagcagat taaaaaaaga tataaagcaa ataaaaaata ttaattaaaa
     5101 aggggaaaaa tgagatgaaa aaattaaatg atgaacttaa agtaaataaa ataataaata
     5161 aaatagaggt taaagatatg gagataaatg cagatccatg taaagtatat tgggaagagc
     5221 atggtctact gcatgaagaa gactgtgata aagactgtgg aacttggcca ttcctaagtc
     5281 ctgaagcttc tgttaaatat taaaacatag aacaataaat aattacttaa atttcttgat
     5341 ttatattttg aagcaatata cattatgata tttaaatatc ataatgtata ttattttgaa
     5401 atataaaatt tataatgagg tagtgataaa tatgatgact aagctgttaa aaggatattt
     5461 tataaaaaat agaaataaat tttttattat agtttttgca attgctgtat gtacaatgat
     5521 tatatttgct aataaagttt cgaaaaacag tcaatctaat tatgttgtaa aagaaactgt
     5581 aaagcaaatg gcggattatc aagcaaagtt taaaaatgta agtaaaagag atttagatat
     5641 aattaaaaac agtgaagata ttaaaaatac aatagtatca aaatactacg gagatataaa
     5701 aacagaacaa aatttttata aattagagag ttataatagt gactcattca aagagcttaa
     5761 aaacactcta atatatggac attatcctag aggtaaaaat gaagtaatta ttgaccttag
     5821 tttttttgaa ttattaaaat cacaaggtaa gataaatatg ccagatgata ataaattcaa
     5881 agaaatatat gttgatttta gatatataaa agaatatcaa aacaacaaag aagaagaagt
     5941 tcttttagat gagacgcaaa actttaaaat agttggtgta tatgatttta gtcaaatgat
     6001 gaagcgttat aaagatgatg gatttagtgt atatgtacat agcgattttg attatcctag
     6061 tgtggcaatt acatataatg gatatataaa tttaaaaaat ggatttaaag gttacacatc
     6121 aaaaactaat aaacttcagg gtgagctcac atctacaaaa agccaattaa ctataaatga
     6181 agatagacaa atggccttat cagataattc ctcgagttta accactcttg ataaatttga
     6241 taaagggata ataatagcgt cactagttat aatttttaat gtatttagca ttatgtctag
     6301 agaaattata agagaaatag gtcttttaag gattgtagga atgagcaaaa aacagtcatt
     6361 tattctactt tttataaaaa atctaattac actaataact ggattaacaa taggtttttt
     6421 attaggatgt atattgtctg tttttatgat aaggtacatg aattttgatt caagtatgtt
     6481 gattgatcct aggaaagcac ctattttaat aactacaaaa tctataacaa atacaattaa
     6541 aacgataact tatatgttta tagtatctac aatagtacca gttctatcaa ttattatgtc
     6601 atatcctata gatatgatat caggtaaatt aaagtttgat ttaaggatag agaataaagt
     6661 attgtctaaa ttaaaaattt ataaaaaaat gaaaaacaaa gtaactagta ttgtatataa
     6721 atattctgac aatataaaac ataataatag aaatatgaaa atgtataatt caaaatacat
     6781 aaaaatgaag ttagcgatga aaaattcaaa gagaaattta gtgtatataa tcacaacagg
     6841 aatactagtt gccatgtcag ggttatacat agtaagtata tttatagata atcaaagtag
     6901 tttagttgac aacaatccat tacttttaaa attaggcgat tatgatatag acttaaatta
     6961 tattggatca gattctattt taggaagagg aatcacagag aaagagataa atgagctaaa
     7021 caatatagat ggtatagaga gtatttattc agtaaagaga agagtagcat tctctagatt
     7081 aaatacaaaa gatttatcaa aggctatgaa aacaacgatg tttttaaatg gaaaagataa
     7141 agaaatagat tatggaatag acttacttag cattaatgaa gatgcatcaa aaaatctttt
     7201 aaatgattat aaaggattaa tagaaaaagg gcaaatgttt gcaccaaata gagacattcc
     7261 agaggttgtt atttttaata agatagaaga ttggtctagt ggaagtagaa acttagtaga
     7321 tgccaataaa aaatacaagc taggagatat aattgatgtg aaaatttcaa tgcaagagaa
     7381 tggtaagctt gtgtataaaa ctgttaaagt taaagtagta gggttcctaa gtgataaatg
     7441 ggagggagtg aacgaaggtt tatcgaatta tcctgatata gttatggatt cttctgactt
     7501 taagaagata acgggagaaa atacttatga tgaaattaaa attaaagtaa atccagataa
     7561 attagaaact gtaaaagaaa gcatagaaaa tagagtaaaa gataataaat caattaaata
     7621 tgatgataga agtagtatag agaaagagat aactcaatat agatggataa atacagtaag
     7681 agaacttttt aatagtatgt tatttgcatt tacagcatca ataaatatat tttttagtgt
     7741 tattacaagt attgaagtta gaagaaaaga atttggaatt atgagatcaa taggtctttc
     7801 attaaaagac ttaaaaggta tattaattag agagggatta atttatggaa tattttcttc
     7861 tatattaggg ctaattttta tatttaatta tggagtaaag ttatcaagta tgttaaaaag
     7921 aatgtcagag cataagcata tagaatatag tggttcttgg tatattctac ctatgtatcc
     7981 tacattaata tttatcatag ttactatctt aatatgtttg ttagcagtag cgttaacatt
     8041 tagaagactt agcaaaaaca tagttgatca gatagacgat atataaaact tttaggaggt
     8101 aattgatgaa aaaagataaa aatttaaaac gttttttaaa atttataatt agtaagaaca
     8161 aactaaaatt atctatatct ttttttcttg tcatagtatc ttcttgtatg agtttatatt
     8221 tacctaaaat tacaagaaaa atagtagatg agggtataat ggctaaagat tacaagttcc
     8281 ttttaaattt aattattata tacttaatta ttgtattttc ttcagctatt atagatatta
     8341 ttttagaata cctttataat gttatgaaaa ataaagttac aagttcattt aaaattaaac
     8401 tttttcatca cctatctaaa ctctcaggaa aatatttctc aaacataaag tcgggaaata
     8461 tcttttcaat agtagaacaa gatttgtata tagtggaagg atttaatgca gaattattat
     8521 tttctataat tatgaatttt ataacagcta tttgttctgt atatttttta tttatgatga
     8581 gcaaggatat gctttttata gttgttattc ttcaaatatt actaatatta tcgcaaagta
     8641 agataagaaa acttatttca aaaatgacaa gagaaataag aaatttagat ggaaatctag
     8701 ctaatatttc tcaagaatat atttctaata taatgaatgt tgttatatca aaatcaaaaa
     8761 aaatattttt aaagagatat ataaaacaaa tgaaatctat aattgagaag aatatgatta
     8821 ttaatttaat tatggtcagc aacatatcta tatctaaaat tttaagtgga atgataagtg
     8881 caactatata tggatatggt ggatataaga taataagtgg aaaattatcg ataggagaac
     8941 ttattgcatt tcagcaatat acaggtatgc tagtaaatcc ttgtataaac ataataagat
     9001 ctgctaataa gattgagcag gtaaaggtat ctatagatcg tatatattct ataatagatg
     9061 aacctataga aatattttcg ccactaaaat caaatatatt tggttcaaat ttagagcata
     9121 aacctataga gaatattgaa tttaaaaatg tatattttaa atatagtgat aaggataatc
     9181 aagtattaaa tggagttaat ttaagttttt ctaagggtaa aacaactgca attgttggag
     9241 ggagtggatg tggaaagtcg acaatatcta atttaatata taggttatgg gatgtatcag
     9301 aaggagaaat tactataaat ggtataaaca taaaaaatgt aaatttagca tttcttagaa
     9361 agaatataaa tgtagtaaca caggatgtac tgatttttga taatactata agggacaaca
     9421 tatcactagg aaaaaatata gaagatgaag aaatactaag tatatgcaat atagttggaa
     9481 tgaaggattt tattgagagt cttgaggatg gactttattc tatagtagga gaaaagggag
     9541 ttaaaatgtc aggaggtcaa aaacaacgta tagcaatggc tagagcattg gctgggaaca
     9601 gtgatatatt agtatttgac gaatccacat cctctcttga taatatatcc caaaaagaaa
     9661 ttatgaaaaa tatgaaagaa gttataaagg acaaaatagt aattataata gctcataggc
     9721 tttcaactat aaaagatgca gacaatattt atgttataaa agatgggcaa gtagccgaat
     9781 ctggatctga tgaagaactt attattttag gaggagatta tagtctacag tgtagtggag
     9841 gggatgtaca ttgagaaaag taaagatagc agtagttgat acagggatag atatagatga
     9901 tgaagagctt aaaaattttt accatataga tgaaagattt caattaaata acgatttaga
     9961 tgttagagat tcaaatggac atggaactct tgtttcaaaa actattatag atatatgtaa
    10021 agatgttgaa ctatatccta ttaaaatatt tgatgaacta ggaaaaacat attctttaaa
    10081 tatagtaata gttttaaaaa aattaattaa ttctgatatt gatttgatta atttgtcagc
    10141 atcaacattt gattatagct atgagaaaga acttagggat gtttgtaagg aactacaaaa
    10201 taaaaataaa ttcttaatat gttcaaaaca taataaaaaa tcagattgtg atagtattcc
    10261 gactgtattt gattctgtta ttggagtttg tggtcatgaa tatatttttt ataaaaatga
    10321 ttatatttat agagcaggtg aaaaagtaaa aatgtacaca aatagtaaag atatttttct
    10381 aagttttaat aagaagatta ctcattttgg gagaaatagt aagtcatgtg cggtggcaac
    10441 aggtattata gctaacttaa taaaaaaata caactatata gagtttaaag aattagagag
    10501 aattcttaaa aaaaatagtc aaagtgaaaa gagcttaaat attaaaaaaa tatccaatat
    10561 caaagataat aaaattaaat ttcaaaatca taaaaatatt aaatatgaag atgttcataa
    10621 tattgaagaa agagtattaa atattattaa taataagttt tcaagtaatg tgaaattacc
    10681 tgatataaaa aaatatggta ttataaataa tttaactaat ataggattat ataatgcgta
    10741 tgaattttta gagtatataa acaatgaatt tagtatagat ataaattata aagatattta
    10801 tatctataat ttatcggatt taaatttact aaagataata ataaggaaat acttaaacta
    10861 aaataagtac tgatgaaaat ttaatgtgaa taaataatta aagagaagat aggtacaaaa
    10921 cttaaaaagg tggattaata atatataatt aatatcatcc ccataataaa ataacaacta
    10981 ttaaataagt ataaaaattt tatattttaa ctaaacaata taggttgaat ttaaggaaag
    11041 gagtatacat atgaagttat taaaggtatc taatttaaaa aagatatatg gtaaaggtaa
    11101 taatgaggtt atagcgatta ataatataag tttagagatt caacctcata aatttacggc
    11161 tatagttgga cagagtggat ctggaaaatc tacattactt cattcaatgg cagggctaga
    11221 taagcctact gagggtaata tatttattga tgatttagat atgtacacat taaatgatga
    11281 caagctatca aaaataagaa gagaagagtt tggatttata tttcaaagct ttaatctgat
    11341 accagttata agtgtgtatg ataacataat acttccagtt tctattagta acaaaaaagt
    11401 ggatacaaaa tatatagata ttttaataaa taaacttgga ctagaaaatc acattagcaa
    11461 atttccaaat gaattatcag gagggcagca acaaagagta gcaatagcaa gagcacttgc
    11521 aaatagacct tctataatat ttgcagatga gccaactggt aacttagatt ctaaaaccac
    11581 agatgaggta attgatattt taaaagtatg tgttaaagaa tttgagcaaa ccttagttat
    11641 gataacacat aataatgaaa tagctaagat ggcagataaa gtaataacta tcaaagatgg
    11701 gcaggttata aattaataga tatagagttt atataatgat gtatctctta gcaaatacct
    11761 taataacata tatattacta tttattatgg aagacatcta aattgcattg attgtatttc
    11821 ttaattatat taaacaaagt acttaatatt tgggtatttt ttttagttaa gtataatgaa
    11881 tgtctgatat aatactagta agaataagat gtaaaagggg gatagtcatg tataaagtct
    11941 gtattgtaga agatataaga gaacaaagaa aaattttagc tgaaaatata gtaaggatat
    12001 tcgaagaagc tggtaaagat gttgaggtaa tatcatttag ttgtggagaa gatcttttag
    12061 gtgcgaatat agataatatt gacatattct ttttagatat agatcttaat aagctaagtg
    12121 gcatggatat agcaaggata ataagaagta aagagataaa ggcagagata atttttacaa
    12181 catctttgat agattatata caagatggat ataaggttag ggcatatcga tatttattaa
    12241 agccaatatc atataagaat ttaaaggaag caatacgatc ttgtataaag gatatagcaa
    12301 aatataaaag atttattaga cttaattata aaaatgtaaa ttataatatt tctattaatg
    12361 aaatattata tattgaagta ataagaaagg atttatatgt atatacagaa gagcgtgaat
    12421 atctcacaaa aaatacaata tcaaatcttg aaaatgaact taaaggattg aattttttca
    12481 gatgtcataa aagttatatt ataaatttag aaaaaattca atctttaact agaaatacaa
    12541 tatatataaa taataatgag ataccagtga gtaaatatag agtaaagaat ttaagagaca
    12601 gattagctga tatattagga gatataatat gttaagcata gtttggaaga taattaattt
    12661 aatttctaca agtatagatt ggattatatt aaaatatcta ctagataaat tagatatgtc
    12721 aaaaaaaagt gaaacaatta cattacttaa tttgattgct tcaattatta taatttttat
    12781 tttgaatgtt attcaaacta atgaaaattt aaaattacta attaacatat ttcttgcaat
    12841 atttttctat aagtataatt atcaagtgag tttaataaaa agtgtgtttg caagtttaat
    12901 cttttatatg gtttttatgg gtctagatac tatatcatca ggaatcatta tactcataaa
    12961 tcaaaatagt gactttaatg ttttattaca taatacatat caacgtttag aattgatttt
    13021 actaactaaa gcattgttat ttatcattgt atattttata aagtttaaga attttagttt
    13081 atctataaat aaaaaagata caataaatat tataattcct atagttgcta atgtaggaag
    13141 cttcatagta atttttttct tagtttttaa agatcaaaaa tttaattttc aggaatcagt
    13201 agttatattc ttaatttcta ttattttaat gatgtcaaat atatctatta tagttgttat
    13261 ttcgaaagta ataagactta atagattaga agttgaaaat tcaataatga aaaataatat
    13321 aaatattcaa tataagtatt attctagttt ggtaagttat cagaaaaaga taagacattt
    13381 acatcatgat ataaataacc atataaatac gttaaaaagt ttgccaaatg attgtgaaat
    13441 ttatgaagaa tatgtgaaga atttagaaga aagggtacta gaaaatcaat atatatataa
    13501 tacagggaat atagttctag atgcaatatt aagagaaaaa cacaataagt gtagtgttga
    13561 gaatataaac ttatcgatag atataaagtt gaatgaagaa ttgtttatta aaccagatga
    13621 tatatgtatt atatttgcta acataattga caatgcaata gaagcatgta gtaaggctaa
    13681 tgaaggtatg attaagtata ttaaattgag agcaacttta gttaataaat tttatgtaat
    13741 aaaatgcgaa aattctagat ttaatgaagt taaaattaat aatcttaaaa tcactacaga
    13801 taagaaagat aaattttttc atggtatagg cctaagtagt gtaaggtatt cagttgaaaa
    13861 atataatggt tatataaaaa taaatactcc aaatgataaa tttgagattt taatatacat
    13921 acctattgga aaattgtcca gttaggtagt taaattgtcc agttgtggat tttatatcat
    13981 aagattcaat gattatgtta tatttataat aataaaaaat aactgagatt tatgtgaata
    14041 aagtacttga ggaggaatag tttatgaaaa atatgaagaa aattataata ggtgtattag
    14101 gtaatttagc tgtttgtaca ttatttatat ctgcaaatac agcttcacca tggatatctt
    14161 atcaaggcaa agaacctgaa aatataaaag aattcaaaat taaaagataa tccaacacta
    14221 tggagagagt aaagtagtta tgattaagtc attagcacga aaagccacct tatttttact
    14281 tgataataaa tcaattaaac ttaatcagta tgagttatat ctatatggtt ttgaaacatt
    14341 aatagctttg attataaata tattagtaat tttacttgtc agtataatat taagtaaatt
    14401 tatagaaact gtattattct tactagttta ctgtacaata aggcagttta ctggggggta
    14461 tcatgctgaa aatcatttta aatgcttatt ggtatttctt ttagtctaca taattaatat
    14521 tattatttta aaatatgtat attataataa tttagagtgg actataattt tattaatgtt
    14581 tatgtcatgt ataggtatat ttaagattgc acctatggag catagagaga agactttatc
    14641 tagtatagac gtggctagtt ataaaaaaat agtaagaatt ttagtaagtt ttagctttgg
    14701 aactatatta tttttgttct tacacaatat ttataatcaa tatatattgt atccagcttc
    14761 agctatagtt tgtatttata taatgttaat cttaggtatt ataaaagaaa agaagctgca
    14821 aatagtttaa ataataatat aatctttttt atatagtttg atatgaaatt aaatatgatt
    14881 aaggttaata cattaattta aaatagctat attaaaatga gtaaatcaaa gtctgtcttt
    14941 attattataa tatgggcagt ctttttaaat ttaacagatt aaaagatcta atcaaattgt
    15001 gttgtatttt cataaaatta agtaaagaac atgactaaag atgaaaacaa aaattaaaga
    15061 atacagaaaa aactccttat gacgaaaaat gaacttgcta aattagttgg ggtaagacgt
    15121 gagactattg tacatttaga aaatgggaaa tataatcttc tgaaacatat agacttataa
    15181 gtgaggttgt atcagatatg tcttgtaagg gtaatttctt caggttcatc aactgtcata
    15241 actctacaga gggtataaga tatgctttgt aagggtaata tatgcttgat tcaagaatta
    15301 gtgttataaa atggattaca taccaaaagg tctattaaaa atatacagtt aaaaagctat
    15361 atagtaagtt aggtaaggtt aataatccaa acaatgattt gatgattaaa ctgtttagag
    15421 ccttagatac aacagtaaaa gaattatttt ttaataagga gaagtaaaag ataaaagaaa
    15481 atcaaaactt aggcagttat tgtagttaca aaataaagga tttccttata tatggataaa
    15541 taatcgagta tatataataa aaaatatatg accttaattt tgttatgaaa taacttcaaa
    15601 acttatttta gcatgtttag attatataaa tcatataaaa aaagtagaat gagtgaatac
    15661 ttatgacaat aatctagtag agatatacat gaaattatat attgactaag tacagttatt
    15721 aatttataat gaaaataaag ttatcataca gataaataaa cggatcgtta ctgagataga
    15781 tgtaatcagg cgtgacctaa aaattctagt aaatgcttaa agtattatta gtctttttta
    15841 ggtctctttt tgtttacagt ggaggtagtt tatggttata aagaaagtat ttaacaacaa
    15901 tgttgtattt gccagagata attcaggaca agaagtaata ttaatgggaa aaggaattgg
    15961 atttaataaa tttactaaag atttagttga aatagataaa attgaaaaga aatttatatt
    16021 caataatgag gaatcattaa gtgaattaca ttcactacta gataggatac ctttaaaaga
    16081 tgttgagctt gtaagtgaaa ttattcaaat gggaagagaa gaattgggtg ataatcttaa
    16141 tgatagtata ttaatcacat tatcagaaca tataagttat atgttaaaaa gaatggatga
    16201 aggattagta tttcaaagcc cgcttcaatg ggaaataaga caaatatatc ctaatgaata
    16261 taattttagt aagaaagctg tagaatattt aagaaaaaaa ttagataaaa atattcctga
    16321 ttctgaaata gcatttatta cgatacactt tgcaaatgct cagttagaaa caaaagatat
    16381 gcaagaaact ttattgttaa ctaagataat tgataatgta ttagatatca taaagtatca
    16441 ctatggaatc gaaataaatg aatattcctt tgactacaca aggtttataa gtcatttaag
    16501 atgttttata aaaaggcaat taagtggtga gaatacaaat gtagacacat cattgttaga
    16561 tataataaaa atgaaatata aaagtgatta caattgtgca aaaaaagtaa aaaactttct
    16621 tgaaaagacg tataaatgga aaattagcga aaatgaattg ttgtacttaa cattgcattt
    16681 aaatagatta tcaaatataa agtaaatagt gtaggattgt tactgtttgg caggcatgac
    16741 ctaagttggt ataattagtt tttaatatct aattgtattg atttaggtct atttttatac
    16801 ataaaattat gaaaatggag gatagattgt atgaaatttg aaagagagtc tgaagaaatt
    16861 ataaaatata tcggaggaaa agaaaatatt attagtttag ttcattgtgc aactaggcta
    16921 cgttttaagt tgaaagatac ttcaaaaact aacaaagaag agttattaaa aatgaaggat
    16981 gtactatctg tagtaaatag tggaggacaa taccaagtgg taattggaaa taaagtaact
    17041 gattactttg aaactattat aaaaaaagca gttttacaag gacaaaatac tgaagaacag
    17101 ggagaaaaag tttcaatagt ttctaaaata tttgaatcaa tttcaggtgc attttctcca
    17161 ttaatacctg cactagctgg agcaggaatg attaaggcac tgcttacaat actaactact
    17221 atgaaatgga tgtctgatac aagtagcact tatgctatat tatcagcagc cggaaatgct
    17281 gtattttact tcttaccaat attcttaggt attactttag ctataaaact tggtacaaat
    17341 ccatatgttg gtggagtgat aggagcagct ttgttagatc ctaattttac agctttaatt
    17401 ggagcaaaag gtggtgctaa cttttttggg atgccagtaa cagcaattga ttattctttt
    17461 ggtgtattcc ctatatttgt tgctatattt atttattact atgttgataa gcttttaaag
    17521 aagattatat taaaagattt acaattattc ttagtaccga tgatatcatt attagtcatg
    17581 gttcctttaa ctgtgatttt atttgggcca atagcaacta atgttggtga tgtaatatcc
    17641 aatattttta tgggattatt tgaatttaac agagtaattg caggagctgc aataggtata
    17701 gctatgccat tcttagcagt attaggacta cactggggct tcacaccaat tactttgcaa
    17761 aacttggcta caatgggtgg agacccaata gaaggtgcag ctgttgcagc agtatttgct
    17821 caaataggta ttgcaatagg cttatttatg aaggttagaa aatctaaaaa aaattcagaa
    17881 ttaaaggtat tagcaggttc aacagcagtt acaggaattt tagcaggagt aacagaacct
    17941 ataatttatg gaattatatt aagatacaga agaatgattc cagtattggc tattgcagga
    18001 ggtattggtg gtggtatatg tggtgtattt ggtgttactt gtaatgcata tgtattccat
    18061 aatatattct caatgccagt ttatacacca ttcctaggat atatattagg aataggaaca
    18121 gcattagtgc taggagcagt attgtcatat ttctttggat tgagtaaaga agaatgtgaa
    18181 gaaggtaatg aagaagttgc ttttgatgaa gatgatggta tagaggagat attatctcca
    18241 atagaaggct tacaaataga gttatctgaa gtagaagatg aagtgtttgc atcaggaact
    18301 ataggtaatg gcatggcaat aataccttca aagggagaag ttgtgtctcc tgtaaatgga
    18361 acaataacaa ctatttttcc tacaaagcat gcaataggaa ttacctctga taaaggtgta
    18421 gaaatattaa tacacgtagg tcttaacact actatgttag atggaaagta ttatactact
    18481 catatgaatg caggagataa agttaaaaaa ggagatagga ttgtttcttt cgataaggat
    18541 aaaatagaag gtgaagggta tagtattgtt acaccaataa tactaactaa cacaaatgat
    18601 ttagcagatg taatagttaa agaaaataaa catattaaaa ttggaatgcc tgtaataaaa
    18661 gttgtttatt aattatactg gaggagatat ttctatgaaa tctaatcaag aatttttatg
    18721 gggaggggca gttgctgccc atcaagttga aggtggatat aataaaggtg gaaaaggaat
    18781 aagtattgca gatgtgatga ctgcaggtac tcatactatt tcaagaaaga taacagatgg
    18841 agtaattgag ggtttaaatt atcctaatca tgaagccatt aatttttatg aaaattataa
    18901 agaagatatt agattatttg ctgaaatggg atataagtgt tttaggacaa gtattgcttg
    18961 gactagaatt tttccaaagg gcgatgaatc aactccaaat gaagatggat tgaaatttta
    19021 tgatgattta tttgatgaat tattaaaata caatatagag ccagtaataa ctttaagcca
    19081 ttttgaaatg ccttatcatt tagtaaaaaa ctatggtgga tggagaaata gaaaattaat
    19141 agatttcttt gtaaacttct gtgaagtggt aatgaataga tacaaggata aagttaagta
    19201 ctggatgact ttcaatgaaa taaataatca aagtataact acaaatccta tttatgcatt
    19261 tactaactcg ggaataatct atgaagagca ggaagacaaa gaagaagtta tgtatcaagc
    19321 agttcattat gaatttgtag caagtgcaaa ggttgtgaag ataggtcatg aaataaaccc
    19381 tgagtttaaa attggatgta tggtggcagc tatgccaagt tatccttatt cttgcaatcc
    19441 agaggatatg attaaatttg tagaatctaa tagagaacaa cttatgttta ctgatgtaca
    19501 tgtaagaggt cattatccaa gacatacact aaaattatgg gaaagaaaaa attataattt
    19561 agatattaca gaggaagata aaaaaatcct aaaagaagga atagttgatt ttattggatg
    19621 tagttattat ttaactactg tagtaacagc tgataaaact atgaaaacaa caggtaatga
    19681 ctcggcagga aaggctgatg tagttgaaaa tccatactta aaaacttctg actggggatg
    19741 gaatatagac cctgtaggtc taagatttta ccttaatcaa ctatatgata agtatgaact
    19801 tcctatattc attgttgaaa atggatttgg agcagaagat gtattaaaat cagataatac
    19861 tgtggatgat gattatagaa tagagtattt ggctagtcat ataagggaaa tgaaaaatgc
    19921 cattgaaatt gatggtgttg atgttatagg gtatactgtt tggggatgta tagacccagt
    19981 atcatttaca acaggagaaa tgaaaaaaag atatggattt atatatgtag ataaaaataa
    20041 tgatggaagt gggactctta aaagatataa aaaaaaatct tttgattggt ataagaaagt
    20101 aataaaattt aatggagaaa ttttatgagt agagaaattt taatatttat aaaattatgt
    20161 taaggaaacc attaaaaatt aggttaaaat cgtgggtatg attcttagga tagtctctac
    20221 catttaaatc cactaaaaga tattgactaa atagtcaata tcttttttat taaaaatgaa
    20281 tataaattta aagaggtaaa gttaaaaatt gggatacata tgatttaata tatagaatat
    20341 tatacaaatt tatttagctt ttagagaaaa ttaatatatg aactggtcta aaactacaat
    20401 gttttaagat tattgtggag gtagtttttt agtaactatt aatggtgaag aagtaactaa
    20461 tatatttata gactgtaaaa tgagagatac ttattataag catactaaat ctaaattagt
    20521 ggaattgaat aagaataaaa aatctttata tcttattgta tctatacata tacatttaga
    20581 ttatataagg agctacacat ttatttagag gaaataaaag taatgagata agaaatatta
    20641 tatagattaa aaatgtagct tataatgtat gtaaaggctt ggaatgataa agaaataaag
    20701 ataacatatt aaattaacga gatgaattaa tatacaaaga gattattagt aatgggaaag
    20761 ctgatttgtc aaatgctgat acatcaaagg atataagtat aaagcaatat ttatttttat
    20821 ctagttatct gttaaaagat gagtacaatt gaagtttatt tagttaattt atagatagca
    20881 ttgtattata ttctatccaa aatacattta aataatgata atgatagtaa tattaatatt
    20941 taaagtatgt tttaaagaaa aaaataccca gattaaaaaa tggattaagg tgaatataaa
    21001 aactatatgc ataaaaatag agataattat agaaaaaaac aataataaaa taagtaatta
    21061 tagaaaaata caattatata gattgttgtt gaatcattga ctgcaagaat aataacattt
    21121 aaaatgaaca tggagaatat gggggaggaa tcaatatgaa gagaaaaata gcagttgttt
    21181 tattaactgt agcaatgtta ttatcacttg tagcttgtag caatgataac acatcaaaaa
    21241 gtgataaatt agaggataca ttagtagtat atactacaca tggagaggat atgctaggag
    21301 caatttctga agaatttaca aaggaaacag gagttaatgt tgaatttata aacttaaaag
    21361 gtgaactagc agaccgtgtt agaagtgaaa aagataatcc acaagcagat ataatgtttg
    21421 gtggagatac atctacatac atgcaattaa aagaagaagg attatatgaa aagactgaac
    21481 caagctggaa taatgaatta gacaagtctt acaaagattc agatggatat tggtatggaa
    21541 ctataaaaac accagtagtg atgttttata acacaaaact attatcagct gataaagcgc
    21601 caaaagattg gagtgattta acaaaagaag aatacaaaga cttaatagtt actagagatt
    21661 cattatcatc atctatgcgt tctactatta gtaacttaat caattactac tcaaatacta
    21721 agagtgaaga agaagcttgg aagtatcttg aggatttaaa taagaatata aagaattact
    21781 acaatagtgg aagtgtcatg tattcagcaa taggtaaagg tgaagctaca atatctgttg
    21841 cagtattaag tgatataata gagaataaag aaaaaaataa tatgccatta gaagttgtag
    21901 atgcagagag cggttctgta gtaatcacag actgtgtagc agctctaaaa aatgcaccac
    21961 atccaaatgc agcagctaaa tttgtagatt ttgttggaag tgctaaggtt caagctatgg
    22021 ttgcaaatga ttttaatcgt attccaacat tagattctgc acttaaagat tcaccaaagt
    22081 ggatgtcaaa agaatataaa gctatggatg tagattggtc tgtaattgga aaaaatcagt
    22141 ctaactggat tgaaaagtgg gaaacagata taatagataa caataaaact ataaaatagc
    22201 ctaattaaat aatttaatat tatatacaaa aatagtgagg attttcctcg ctattttacg
    22261 tataaggaaa ctatagtatc tcataatttt gtataattca tacaacaaaa tgatactaat
    22321 acatacttat taaataaaat agtttttgag caactgatga agtaattgac tatataaagt
    22381 gatttgtaga catagtctct caaataaagt aaatttttta ttatgcaaaa cttttaatta
    22441 tagtaaaagt acaatttata tgggcaagga gataaaaatg gaactaaaaa ttagtgatta
    22501 taaattatta tgtaataaag gtagtggcgc ttttaacgaa gatatcgtag gtttatcacc
    22561 ttatggggca tgggtacttg atggagctac aggtttaaat aataaaaatt tagtctctac
    22621 agaaagtgat gccaaatggt atgtaagttg gtggaatagt tatcttcatg agaatatgga
    22681 aagagaagat agcttaaaag taattattaa agaaggcatt gaggagataa caaaagagta
    22741 ctacaaatta acagatgata aagaagtaga agcaatagat attccttctt gttcatgttc
    22801 tatattaaag ttttataaag ataagataga gtatttactt ttaggagatt gtactttatt
    22861 agttaacaat aatgaatctg tgaaaatttt aaaagatgag actttatgtg aacttgataa
    22921 aaaagcattt gattttatga aagaagccaa agatgctaca aaccttactt taaaggagag
    22981 aaaagccgag gtaatgccga ttataataga gaatagactt aagaaaaata ctgtgggggg
    23041 atattggact ttggaatttt ctaaagaggc cgttgacaat tgtgtaagtg gatttattga
    23101 tatagaatat aaaatgaaaa ttatgatggc tagtgatggt ttttcatgtg gatatgatag
    23161 atataagatt tttgataaaa atgaaatgat gaaaatagca gagattaaag gtatagatta
    23221 tatatataga aaggttaggg aactagaaaa ggatgatgaa atggcaatag agtttcctag
    23281 atttaaaatc tatgatgatt catcatgtgt atatttagag atttataaat attagataat
    23341 ttatggagac gatatgaaga atatagaatt aaaagaaatt aatcattatt atggaaaaga
    23401 aaaagtatta catgatatta atatatctat taaggaagga gagtttttta ctttactagg
    23461 tccttctgga tgtggaaaaa cgactatttt aagaataatt ggtggattta taaaaccttc
    23521 ttctggaagt atttatgttg gtgataaaaa cattaccaat ttagaaccag aaaatagaaa
    23581 tatgggaact gtttttcaaa actatgcact gtttccaaat atgacagttg aagaaaatgt
    23641 atcttatgga ttgaaaataa aaaagctgtc taaaaaaatt ataaaggaaa aatgtgataa
    23701 ttatttagag ctggcaggaa tgaaagattt taggaaaaaa aagattgatg aattatctgg
    23761 tggacagcaa caaagggtgg cagtagcaag gtcattagcg actgagccta ctatgctttt
    23821 attagatgag ccaatgtcta atctagatat agctttaaga atcaagatga gagaagaaat
    23881 aagagagata cagcaaaaga caggtattac tactttattt attacccatg atcaacaaga
    23941 agccttagct atttctgata gaatcgctgt aatggataag ggtaaagttc ttcaaattgg
    24001 tgtgccaata gaagtttaca aaagcccatt gaatgatttt gtagcaaact ttgtaggtac
    24061 ttcaaactgt attgaaaaag aagattatgt taattttaat attgaaaaag agacaaagcc
    24121 ttatatttat aaaagacctg aagaaatgat attattgcaa aatacaaatc aaagtggttt
    24181 tgtaaaagta aaagtagaat ctaagaattt tctaggagca attttagaat atacagtatc
    24241 aaatgatggg aaaaaatatc aagtaactga gcttaataga ctgaataata gcaataaatt
    24301 aaacgtaggg gatatggcat atttaggtgt gctacaaggt gattaatatg attaaaaaaa
    24361 taaaccgtag taaatttaca tctaaaaatg ttatttttat tgttttatac agtatattat
    24421 tttggatttt gattggatat attatcatac caataggcaa tacttttgta caagcattcc
    24481 aaggtaaagg tggatattct tttgaagttt ttaaagaata tttttcaaat actaataatt
    24541 taagggtagt aagcaatact ataattttgg gattgggttc tgtgttcgta tgtggaatta
    24601 tgggaatatc acttgcctta tatatgacat ttgtttgtga taaacataag aaaatcatac
    24661 atattctttt actaagtcca atgatgattc ctggagtaat tatggtaatt gcatgtattc
    24721 agatttatgg agaaagtgga atagttacaa aatctataga aattttactc ccctttatca
    24781 aaaaacctta tgattttagt ggattaaagg gaattttatt tgtggttgcc tatactcagt
    24841 atgtatattt ttatttaaat gtatatgttg ccttaaaata tgtggattac tcaacagttg
    24901 aagctgcaaa aggaatggga gcatcaaagc taagagtatt ttttgatgta atatggcctg
    24961 ttattacacc tgctgttata acttctacta ttataacttt tgcatcaggg attagttctt
    25021 tctcagctcc aaatcttata ggtggtggtt ttaaagtttt aagcactcaa attgttaggt
    25081 ctaaggctaa taaccatatg gatatagctt cagttcaagt aattacttta ttactaatgg
    25141 ggattttatt tatgatttta ttacagtatt atggcaaaaa atatggagta gtgccatcct
    25201 taaaatctca aagttataaa gttcataata gaaaaaaaga cttatttaca tttgtatgta
    25261 aggttattat tgaaatacaa attattatga ttatgcttcc tatagttact attgtgtatt
    25321 tatcctttgt aagcacacat tcaattatga caaccatatt tcctagagac tttacactgg
    25381 aaaactatca gatgattttc caaaaatcac gtgtattaca gcctatatta aatagtttca
    25441 aaatgtcttt aatggcagta gcagtaggat tgataattac tgtaccagta tcatatttag
    25501 taattaaaaa ggatactgca tataatcgac tagcaaaatt tattataatg ttaccttgga
    25561 gtatgcctgc aagcgccatt gcagttaacc taattaatac atttaatcaa aaaagtatat
    25621 ttgcttttaa tgaatcctta ataggaggtt tttatattgt acctatagca tatacaattt
    25681 atgctctacc attattattt tcatccaatg aggttgctat gaagtcaata aatttaggac
    25741 tagaagaatc atcaaggagt ttaggtgctg gaaggataaa aaccttttat aatgtaatag
    25801 ttccaaatat gatgccagga ataatttcag gagctatatt agtattcatt cgtacaattg
    25861 gggaatatac aatgtcagcc ttgctttatg gtgtttataa tagacctatt tcaatttcta
    25921 ttgtaactaa tatgcaagaa tttaagatag gagtatctat ggcttatggt gtattagtaa
    25981 ttggtatatg ctatatagca ttaggaataa tttttaaatt agatagaaaa agatttacat
    26041 aagataacaa ggctaattta taaattggtg cttagaaaac caaatcactt tattagctaa
    26101 agatgaattt gaagggtgac actttggtgt tttatgtaaa gtttatggaa gtaaaacatt
    26161 aaataatcgt gagtatgatt cctataaatc gtatatacta ttgaaatcca agaaaaggta
    26221 ttggctaaat agctaatatc tttttaattt tttgactccc atatagcatt aactattaca
    26281 tgagtatctt taaatttata gttaaagtat cttaattgtt tattataaaa atataggatg
    26341 gctaaagcac attaaattaa aacacttaaa aagagaagat gtacatgaga aatataatta
    26401 actatgatac agacttctaa aaattattta gtgaaaagga acttagagtg tataataaaa
    26461 gttccttttc aataaggaaa acgattgtta ttttctgacc ttcattaccc tgatattatt
    26521 taaatataaa caacaacaaa attaacaaga agcaaattca acctaaaatt taaactatcg
    26581 ggaggtacaa tatgttaatc aatatgaagg aaatgctaaa agtggcacaa gaaaatcaat
    26641 ttgctgtacc agcatttaat ataggaagtg ggcaaatact taaagcagta gtacagagtg
    26701 ctaacgaaaa aaatgcacca gtaatacttg caatacaccc aaatgagcta agttttctag
    26761 gcgatagctt tgtagttagt tgcatagaag aagcgaataa gagtaaagta cctatggtaa
    26821 tacacttaga tcatggggaa aataaagaac aaatattaag ggcaataaga tgtggattta
    26881 catcagtaat gattgatggc tcacatttac catatgaaga gaatgtagct atatctaggg
    26941 aaatagtaga aatagcaaaa ggattaaatg tgtccgtaga aggagaactt ggaacaatag
    27001 gaacaacagg aacatcaagt gaaggtggta ctgatgaaat aatatataca gattcaaaat
    27061 tagctaagga ttttgttgaa aaaacaggag tagacacact agctattgca attggtacag
    27121 cacatggtat atatccaaaa ggttttaaac cagagcttaa actaaattta ttaaaagaaa
    27181 taaaagaagt agtagatata cctttagttc ttcatggtgg ttcatcaaat ccagatgaag
    27241 aaatagcaca agcagttaaa ctaggagttt gtaaaataaa tatttcgagt gatgttaagt
    27301 cggcatatta taagaagtgc agagaactat tagaacaaac cccaaactta tatgagccag
    27361 atactatata tccaccatgt ataaaagctg caagagaagt tatagagttt aaaatgaatc
    27421 tattcaatgc tatagataag ttaaagtgct tttataaaaa taaaaattaa ttatgaggta
    27481 acaaattaaa aggaggggag aatttatgat aggtaaaata ctacgaagcg attgtattgt
    27541 actagataaa caattacaaa caaaaaaaga tgtgattaat tatatggcaa atcatttgta
    27601 ccatggaaat tatataaata ataaagaaaa gtttatagct gatattaata aacgtgaaaa
    27661 agaatcatca actaatatgg gtaatttaat agctatacct catgctaagt caagtgtagt
    27721 aaatcaacct gtaatgatgt atttaagaac agatagagag attacagata atgatggtca
    27781 aaaacttagg tcatttttta tgatagcagt tccagaatca ggttcagatg aacatcttaa
    27841 gattatatct aaactagcta catatctaat ggaagaaaat tttcttaagc atctactaag
    27901 tgcagaaact ccatacgaaa tattaagtat atttaataac aaagctgcag aatcaggaga
    27961 ttttagtaat aatcaaaata aaggtcttat agttgggata acaggatgtc caacaggtat
    28021 agctcatact tttatggcaa aaaaagcatt agaggaagca gggcaagaac ttggatatga
    28081 agttaaaata gaaactcatg gagctatagg tgtagaaaac aagttgacta aagaagatat
    28141 aaaaagagct gaatacgtaa taatagcttg tgataaagaa gttcaaatga gtagatttat
    28201 aggaaagaaa gtgttacaaa agaaagtagt agatgctaag aatgtttcat tagctaaaaa
    28261 tttaattata aacgctgaaa atggaatggc taaagaaatt aaaccaggtg gaaagacttt
    28321 agaagattca aaagaaatgc ttcaagggtc agagacaaag ggtgtttata agcacttaat
    28381 gagtggtgta tctgaaatga ttccatttgt agtgataggt ggaattggta tagccatagc
    28441 atttatgttt ggtatatttg catcagaccc aactcatgaa acatacaacc ctatagctgg
    28501 attctttgga caacttggag gcgattcagc atttaagtta tttataccgg tacttgctgg
    28561 ttttatagct aaatcaatag caggaagaca aggatttgct cctgctatga tagctggttt
    28621 tatggcagtt attggaggtt cagggtttat aggtggtatg gtagctggtt ttgcaacagg
    28681 atatatagct ttaggagtaa tgaagataac agaaaattta ccagatgtat taaaaggagt
    28741 aaatgctgta ttgatatgtc cacttttgat tgcatttacg agtggagcta taatgttctt
    28801 tgtagttaat acgccagcat catggttaaa tgaagcttta caatcttggt tacaaagtat
    28861 gtctggaact aataaagtat tattaggtgc aatattagca gggatgatgg catcagatat
    28921 gggaggacct attaataaaa cagcttcagc ttttggattg gctatgtttt caagtaatat
    28981 atttgagcca tcagcagcac taatggtagg aggaatggta cctccattag cgatatcatt
    29041 agctatgtta atattcaaaa ataagtttac taaagaagaa agaaagtcat ctctaccaac
    29101 tgctataatg ggggcatctt tcataacaga aggcgcaata ccgtttgcag ctgcagaccc
    29161 attaagaatg attccagcaa atataattgg ttcttgtata ggtggggcaa tatgtatgag
    29221 tttagatata actttaatgg caccacatgg gggaatattt gtaataccat ttgcatgtag
    29281 tgcaccagtt gcatatatag cttgtatatt gattggtaca gtaataacag cattgattat
    29341 aggggtagca aagcctacta taagaagtga aaacagtgaa gttgaattac ttggtgctta
    29401 aattataaat aatagtaaaa ataattaatg gaataacaac aagtatatag aataataata
    29461 aggatattta gaatcagtta actacttcta aatatcctta atttttattt tgaaattata
    29521 ttatctatta tattaattta gtaaggtgta tcataaattc ttttatgata cagaagtatc
    29581 ttagtaattt tacatagtta gtaaatatgt taaaatagta cttaatataa acatagaaat
    29641 atataaacat aggtagggag ggctaagtat gcttgtgtcg aggcaaattg aatttcttaa
    29701 attgatacta aacgaaaata aatatagacc tataaaatac tttaaagata aattaaatgt
    29761 atctgataaa actttacaaa aagatttgaa gatgattgag aaatatttag aaacttttaa
    29821 tataaaaatt gatataaaaa gaggctatgg aatattaata gaagatttag caaagaagaa
    29881 catagactta attaatagtt taaatataca atcgaaggaa aataaatctt tatcagtaga
    29941 gcagagaaga atggagattt taaagtattt attactaaat tcaaataata taacttcaat
    30001 aaatcagtta gcagataaat attatgtaag taaaacttct atagtaaatg attttaaata
    30061 tatagaggca tggataaaag aatacaattt aaaacttaat aaaactttag aaggaactaa
    30121 gattataggt aaagaagtgg atataaggaa atcgattgcc aaaatgatgg atgatttatt
    30181 agatgaaaat tatgaacaac atgatatatc tgagttaaca agattagatt ctgctacatt
    30241 tagtgcattg ataaatttat ttgatattga ttctattata tttgtagaaa ctataattac
    30301 agaattagaa tacaatttag gatatactat aaatcagccc tactatataa atttaattac
    30361 ccatatactt atatgtttaa agagaatcga agaaggtaat caaatagaat ctcaggaaga
    30421 aagagaaatt tctgtagata atttggacga gttagtatat aaaaatgtca ctacacttat
    30481 agataaaata gaaaatagat acagagtaaa aataacgaaa gatgaaatta tgtacatata
    30541 tatttttttg gtatcatctg gatttagtag cgaaaataat agtagttata atgatgaatc
    30601 agatatatta agtgaaagtg aaaaagtttc atctataatg atagagaata tgtcacaatt
    30661 tttaaatata aatctcaaaa atgatgactt actacaaaaa agtctagcat ctcatgtaag
    30721 gcctatgtta aacagattaa gatatgatat ccaaataaaa aacccgttgt taggagagat
    30781 acaagagcga ttttcagatg tgctgggatt atgtatgatg actataaata ttatgacaga
    30841 gtatgataat ctgaagaata ttagtataga tgaagtttcg tatcttgcca catattttca
    30901 agcggcaata gaaagaaata tgagtagtaa aagagtaata gtagtttgtc atacaggata
    30961 tggaacatct cagctccttg cagccagatt aaaaagagaa tttcctgaat ggactatagt
    31021 tgatatagtt cctatgcatc agttgagtaa gcgaaattta gatgatgtag actttgtaat
    31081 atctactgta aacttagatt tgaaagataa attacatata gttgtatcag tactattaat
    31141 ggaaagtgat attaataata taaaaaatgc tttactttct aaacctaaaa aaagtatgaa
    31201 cttagataca aacttattag gaatgtattt agaagataat atatatttta attttgatgt
    31261 agctcagatg gaaagtttaa taggtgtgaa tttagggagt aaatatgaat ctatttcatt
    31321 aggaaaagat ttgaatatat atatacataa gcaaagtaaa ttaaataaag ggataatgaa
    31381 tatcaataat gttactagaa cgattgatat ttatttagaa attagtaatc aaagtttttt
    31441 aaagaatatt ttaatggaaa tatcaaattt atataggcaa aagaactata taaactatat
    31501 aatagattgc aagagcaaag aggatattaa aatattattt aagaataatc tattggagaa
    31561 aacaaatgga aattagagaa atattaacag aagaaagcat tattttagat ttgaaatcaa
    31621 ctacaaaaga aggcataata caggaattag tagataaatt atacgataca ggaagtataa
    31681 ctttaaaaag taagtttata aaggcattaa aacatagaga aaaaataggc tctactagta
    31741 taggttatca aatggccatg ccacatggaa aaacaaaata tgtaaagaag gcatccatag
    31801 taataggtaa atctaaaaaa ggtgtagatt ggccaagtat agatggctta cctgtaaagg
    31861 taataattat gtttgctatg ccacaatctg gaggcaatga agatatgata ttaatatcta
    31921 aaatagctta cattttaggt ggtaaaagta taagtgaaag acttttaaat gcacatacaa
    31981 aaaaagaaat attagatata ttttatgaag tgtaggtatt gtataaatta taaatttgag
    32041 gtttttaaaa taaaatgtgt attcttttaa atagtataga ttaattttta gacactagag
    32101 aggagaggat atctatggca atatatttag aaatgcctaa attaatacat gaatttcctt
    32161 ttcgtagtct atcaaatgaa ggagaagtat taacaacacc acactggcat aaggaaatag
    32221 aaatattact tataacagaa ggtgtagtaa atctatttat aaatgataag cctatgcaat
    32281 taaaaaaagg cgagatagtg ataataaaag gaggagatat tcattatata ctgccatcac
    32341 cgggaagtga aagattagta tttcaatttg atatatcttt ttttaatgat ttaattttat
    32401 taaatgagga aaaagaaagc ttaattaatt tattcagtag tataaaaaaa tgtagtagag
    32461 attggtcagc aaaaataaga aagtcagttt tcgatatatt gatagatatc tacaatgaag
    32521 acctatacaa aatagaagga tatagttatg caataaaagg taaaatgtat aatttaattc
    32581 ctatattata tagacagatt cctagagaaa ttgaagaaaa tacagtagaa tatgaaataa
    32641 actctaaaga gatattagag agattgaaca atatattcaa atatgtagaa aaaaattata
    32701 aacaacctat aaaattagaa gatgtgtctt atgaagtagg atttagtgta tattatttta
    32761 ctaaattttt caaaaaaaat acaggaaaaa catttataac ttttttaaat gaatatagat
    32821 tagaaaaagc aaagtggata ttacttaata acaatatatc cattgtagat ttggttgaag
    32881 aagttggttt tggaagtaca aaaacttttt acagagtatt taaagaaaaa attggagtct
    32941 ctccattaga atttaaaaaa agatataata gcttggagaa aaaagggggt gcctcaaaat
    33001 gaacttagtt catgaggcac tttcttttat atgaaatcaa atatattttc agtatttcaa
    33061 caatgaaaat tccattcatt tataaagtct aaattttagt tctcaataca acctctattt
    33121 cgaaataaat ccttttatat atataaatat acagcaatat atgagaataa gataacaata
    33181 atgaggatat aaaaatgtat ttgctatata tataattata tacatagata tctaatattg
    33241 atatttaata tgaaagtatt gaaaatagac aatattaatt atagtgagta aaaaatataa
    33301 ttggattttt aaattgaatt atttaaaagg tatagtatga aaaaaatctt ataactaaat
    33361 atgagataga aattataaaa ctttatactg tgaaagaggt agatgcatga aattagggaa
    33421 agatttttta tggggagggg caatttcagc caatcaaagt gaaggatttt atttagatgg
    33481 aggaaaaggt ttatctcagt ttgataaact cccattaaat gataagagat taaaagatgt
    33541 atgtttagat gaggataata ttttaaatga aaataatcaa tactatccaa gtcatatagg
    33601 gattaaattt tgtgaaaatt acaaagaaga tatagcaatg ttagcagaaa taggttttaa
    33661 atgttttaga ttttctatat cttggtcaag aatattccca acaggagaag aaagtgaacc
    33721 aaatgaaaag ggattacaac tttatgataa tataataaaa gaattaaaaa aatataatat
    33781 agagccatta ataacgataa gccactttga tataccttat tctctagttg aaaaatattc
    33841 tgggtgggct gatagaagag tggttaattt atatgtaaaa tatgctgaaa ttttgatgaa
    33901 aagatataaa gatgatgtca aatactggat tccttttaac gaaatgaata tgataatgca
    33961 tattccatat ataggtgctg ggttaacttt tatagctgat gaaaatcaac ttcagaaaaa
    34021 atatcaagca gcacaccatc aattattagc taatgcaaaa actatagaaa taggaaggta
    34081 tataaataaa gaatttaagt ttgggtgtat gttagctgct ggaaaaacat atccatacac
    34141 atgtaaacca gaagatgtat ttgcaacttt agagcatgaa aggcataatt tgtttttttc
    34201 tgatgttcaa gttaggggtg tgtatccaag ctttatgaat tattatttaa aatcaaatca
    34261 aatcaaatta ataataaaag aggaagattt atcaacactt aaggataata ctgtagattt
    34321 tgtatctttt agctactatt ctagtgcttg tagttcagct agagctgaag gtttagaaaa
    34381 atcaaaggca aacggaccag aaaccataaa aaatccatat cttccaaaat caaatagtgt
    34441 atggcaaaac gaccctgtag ggttaagaat aactatgaat cagttatatg aaaggtatca
    34501 gttaccttta tttatagtag aaaatggact gggtactcaa gatattgtaa atgaagatgg
    34561 aaaaataatt gatgattatc gtatagatta catgaaagaa catattaaaa atatgattct
    34621 tggagtaaat gaagatggaa tagagcttat aggatatctt atgtggggat gtatagatgt
    34681 aaccagtgta agtgaaggaa agatgacaaa acgatatggc ataattcatg ttgattctga
    34741 tgactatgga agaggctcat ttaaaagaac taaaaaacaa agtgcttttt ggtataaaaa
    34801 agtaatagaa acagatggag aaattttatt taatgatatg gaaactcatg cataattcat
    34861 tttaagaaag gagtgttatt atgagtttaa tatttactac taaggaccaa cttatagagc
    34921 aagggtttag taaggataca ataaaatcca atgaaacgtt gtttacacta gctaatggac
    34981 atttaggagt tagagggaat attgaagagt ctgattttaa taatgagtat gtagataata
    35041 tgggtacata tgtaaatgga ttttatgaag aatctccaat tacatatgga gaaagcgctt
    35101 atggctatgc aaaacaaaat cagactatct gtaagttacc taatgctcat atagtaaatt
    35161 tctctattga aggagattgc tttgatttat caaaaggtat tacaagtgaa catactagga
    35221 tactagattt aaatgaaggg attcttaaac gttcatttat atgggaaaac tctcgtggta
    35281 gaaaagttaa agtatctata gaaagattag tatcacaaga tatagaagaa ttaatgatga
    35341 tttcatatac aataacacca ttgaatttta atggaaaaat aaaatttaaa aataaaatgg
    35401 aaaatagtat ggagaagttt aattgtgaaa aagtagatga cccaagagtg gcatctataa
    35461 ataagaagca atttaaaatt aatgtaaaaa aatataacaa taagtatttt atgaatttag
    35521 ttacagaaag aagtagatta gggttatggt gtgggtttga ttcatatatt acttgtggaa
    35581 atattacaaa tgagacctat aatgtttcag atgaatgtat tgagcgagaa atagaagtct
    35641 atgccaaaaa agatgaaagg ttaaatttag aaattgttgt aggctatagt agagtatatt
    35701 ctgatttaaa tctaaatgaa gaacgtttaa aatcattaga atgtctggag tcgttaaaat
    35761 gtttagaatc agaagcacat ttaaaatcat tagaattggt tttaagagaa gcatgtaata
    35821 ttggatttga taaagtcaaa aatattcaga gaaagaaaat gaatgagttt tggacaacct
    35881 ctgatgtaga gattgaaggc gataaaactc ttcaactggg tataaaaacc aatttatttc
    35941 atatttatca atcagcagga agagatggaa agactaatat atcagcaaaa ggtcttacag
    36001 gtgatggcta tgaggggcat tatttctggg atacggagat gtatatatta ccatttttta
    36061 tatatactca accatccatt gctagagctt tattagatta tagatattca atcttagatg
    36121 catcaagaga aagagctagg gagcttggaa taaataaagg ttgcttatat tcatggagaa
    36181 ctataaatgg taatgaatgc agtgcatatt atccagcagg aacagcacag tttcatataa
    36241 atgcagatat agcttatggt attagaatgt attttgaagc aactaatgat gaagaattta
    36301 tgatgcaaaa tggcttagaa attcttatag aaacagcaag attttgggtt gaatttggag
    36361 attatataga attaaaaaat aataaattct gtataaatgg agtaacagga ccagatgaat
    36421 atacagcaat agtaaacaat aattactaca ctaatttaat ggctaaatat aatttaatat
    36481 atgcagtaca gatggtagat aaatttaagc ataatttatt ttcaaatgaa gtatttagaa
    36541 aagttaaatt acaagaatat gaagtaaaag actggataaa tgccgctcaa aatatgtatt
    36601 taccatatga tgaagagaag aaaataagca aacaagacga ttcattttta gaaaaatcag
    36661 tatgggattt taaaaataca ccaaaagaaa aatatccatt acttctccat tatcatccat
    36721 taacaatata tagatatcaa gtaaataaac aagcagatac tgtactttca gcgttgcttt
    36781 tccctgatga gtttagctta gaacaaaaga agagagattt tgaatactat gaaaaaataa
    36841 ctactcatga ttcatctttg tcaaggtcaa tatttggaat gatggcaagt gaaattggaa
    36901 atcatgaaaa agcttatagc tattttatgg acacagcatt aatggatatt aataacctac
    36961 aaaaaaatac aagtgatgga atacatgctg ctaatatggg tggaacatgg atgagcttag
    37021 tatatggatt tgcaggaatg aaaataaaaa aggataaatt aagttttgaa cctaggatac
    37081 ctaaacactg gaaaaacatt aaatttaata tcttgtttag agataattta gtttctgtaa
    37141 atatagaaga atataaatct tattataagt taatcaaagg taaaaacata agcatattac
    37201 atgataataa agaaataaaa ttatcaaaga acataataga agttaataat tgttttaaag
    37261 ggagtaatta atatgaaagc agtcttattt gatcttgatg gagttataac agatactgct
    37321 aagtatcatt ttgaagcttg gcatgagata gcaaaatcgc tagatataga aatagatgaa
    37381 acttttaatg aaaaattaaa aggcataagc agggaagaat cattagataa aatattgtta
    37441 tctgctaata aagtagatag ttatactaaa gaggaaaagt taaaggtgtg tgaagaaaaa
    37501 aataacattt atataaagtt aataaactca ttaacatata aagatatatt accagggata
    37561 aatgagctta taaaagaact taaaaaaaat aatgtgaaat tgggaatagc atctgctagt
    37621 aagaatgcac ctaggatatt agaatctttg ggaataaaag atgaatttga ttgtatagta
    37681 aatccatcct tattagaaag gggaaaacca tatcctgata tttttattga agggagcaag
    37741 atgctaaatt taaaacaata tgattgtgta ggaatagaag attcttattc aggtattaaa
    37801 gctataaatg ctgccaatat gacatcaatt ggtgtgggga aaaaagaagt actaggaaaa
    37861 tgtgaccata ttgtagaaga tactagctta ttaaattaca atacactatt acaagcttgg
    37921 agtaaaaaga ttaatttgga ttaaaattat attaaaaatt attttaaaag agaggataag
    37981 gtatgaagaa taaatatgaa gaagtagctc aattgataat tgatggactt ggaggaaagg
    38041 ataatataat tgacttaact cattgtatga cacgattaag gttcatctta aaagatgaaa
    38101 agaaagtcaa tgcagataaa ttaaaatcta tagataaggt agttggagta aactcaactt
    38161 caactcaata tcaggtcata ataggtaatg aggtaggtgt tgtatttaat gcaataataa
    38221 ataaggggat aaataccaca ggagatatta aaagcgatat aaaaaatgaa aataaaaaaa
    38281 atagtatttt aaataatata atagacacaa taactggttg tatgacacct atgataccag
    38341 cccttacagc atctgggatg ataaaagtta tattatctct ttgtaccact tttaattggc
    38401 tatcatcaaa ttcaagtaca tatagagtat tagatataat aggagatgta gcattttact
    38461 ttatgcctat aatacttgca ataaatgcag ctaaaaaatt taatgttaat acatcaatag
    38521 cagttatagt agtaggtgtg tttttacatc caaatttctc tgcatgggta tcaagtgggg
    38581 accctatatc atttatagga gtaccaattc aaggtgttat atatgcagca tctgttatcc
    38641 ctgcactttt aacagtatgg atgatgtcat atatagaaaa attcattgat aaattaatac
    38701 ctagcatgtt aaaaacaatt ttaaatccaa ctttagtatt attaataagt gcgccaatag
    38761 cattaatagt aattggacca ataggaaatt tcttaggaga gggattagct agtataataa
    38821 atttactaca aggaaagtta ggatttataa tggtttgttt attagcagct gcaatgccat
    38881 ttatcgttat gacagggatg catcatgcat tgactcctat attcatatca gcatttgcaa
    38941 ctacaggaca agaatcgcta atattaatat ctcaagtttg tgctaattta gcgcaaggtg
    39001 gcgcgacatt agctgtagca ttaagaagca aagatagtaa gatgaaacag ttagcatcag
    39061 ctgcatggat atcagctatc atgggtataa ctgaaccagc tctttatgga gttacattga
    39121 aacttaaaaa acctgctatg ttagcatcta taggagcagg aatcgcaggg ttatttgcag
    39181 gaattactca tgtgacttta tatgttccac aaaatagtat aatggcagta cttggattat
    39241 caggagaaaa ggggatttca aatatagtaa atggacttat agttatattt atagcattgg
    39301 ttgctccatt tattatgaca tatgtttttg gagttgaaaa aaatgttaag gaaagtacag
    39361 ataatgtagt agaggaagta taatattaac tatttacatt aatagaattt ttattattat
    39421 tgactataac ttgttttgta tttatattga tgcaaagaaa taagttaata ttaatgataa
    39481 taattattat aactgacaaa aagcaacaca aaagattgat gaagtatatg gaaataaaaa
    39541 gttgacaaaa tatgtctgat gttttatcat attaattgga attaggtagt aattgtttaa
    39601 gtacaagcta agcttattca ttaataatag cagtatccta ggaaggagta tgcccattat
    39661 tatggataag ctttttttat gcttaaaagg aggataatca tgataattaa taagatatta
    39721 aacaataatg ttgtaatcac attagatgat aatgatgaag aagttatcgt tatgggtaaa
    39781 ggaattggtt atcaaaaatc aaaaggcaat ctaatagata aaactaaagt aaataaagta
    39841 tttagaatat caaataaaga aatatcaaac aaactacaag aattactcaa taatattcct
    39901 atagaacaca tgaaattatc aagtgaaatt atagaatacg cacaaataaa gttaaacaag
    39961 aagctaaatg aaagtattta catatcctta agtgaccata catattctgc aattcaaaga
    40021 atgaaagaag gaataaatgt aaaaaatgca attctttggg aaattaaaag attttataaa
    40081 gaagagtttg aaattggaat gaaagcacta gatattattg aaaacaaaac aggtataaaa
    40141 ttaccagaag atgaggctgg atttatagcc tttcatatag tgaatgctca gttaagtgaa
    40201 ggtcatactt tggcatctga tattacgaag ttaatacaag aagtacttag catagttagg
    40261 tatcatttta ggatagaatt tcatgaagaa tcagtgtttt attatagatt tataatgcat
    40321 ttaaagtttt ttgcgcaaag attgctttta gatagtgcac atgaaggtga gacagacaaa
    40381 gaattactaa gcattattaa atctaaatat aataaagagt ttgaatgtgt agttaaaatt
    40441 aaaaatttca ttaaaaaaca atataactac atattaacag atgatgagct tatatattta
    40501 acaatacatt tagctaaagt agttaaagac tcaaatatgt aagtgaaata atttttcagt
    40561 agtatattaa gaatgattga aaggagtgat actaacaaaa ttatacctat ggttggatgg
    40621 taacattgag ttggccaaac cttcaaattt caaaaaatta atttaaacga aatatggagg
    40681 agaaaaatgg gaaaatacaa acaattagca caagagatag taaacaatgt tggtggaaaa
    40741 gaaaatatta gtggattagt acactgtatt acaagattac gttttacttt aaaagatgaa
    40801 agtatagcaa atgacaatgt attaaaaaac atggaaggta ttgttactgt aatgaaaagt
    40861 ggaggacaat atcaagtagt tataggaaat catgttgaag ctgtctataa agatgtagtt
    40921 gaaataattg gtttagatga ttcaagtaca agttcagaaa ctaaaaaatc aggcaatata
    40981 ctagataaag gtatagatat aatatcagga atttttcagc cagtgttagg aataatggca
    41041 gcttgtggta tgttgaaagg atttaatgca ttatttgtag caatgggatt atatagtgat
    41101 gtatctggtg gttatatggt aataaatgca gcaggagatg cattatttac attccttcct
    41161 ttgttcttag gatatacttc agctaagaag tttggattaa aaccaatgtt gggattagca
    41221 ctaggagctg cagtatgtta tcctgctata caaggtagca gtatatcagc aggagcagat
    41281 gtgatgtaca ctttatttaa aggaacaatg tttgcatcac cagtatatat tgatttcttt
    41341 ggactaccaa ttgtatcaat tgattatact ggaacagtcg taccaattat atttatagtg
    41401 tattttgctt ctaggtgtga aaaattattt aataagtttg ttccagattt agttaagttt
    41461 ttctttgtgc caatgcttac attattaata acagtgcctg ttgcacttat agttataggt
    41521 cctatcgcaa catttggttc tacacttatt tcacaaattg taatttcaat aagagatttt
    41581 agtccactat tggcaggtgc tatagtaggg tttacttggc aaattcttgt tatttttggt
    41641 atgcactggg gatttattcc tgtatatata aacaatgtta tgactttagg atatgataat
    41701 gttatgatgc cattctttgc ttgtacattt gcaagttcgg cagttgtgtt ggcaatattt
    41761 ttcaagacta aagataaaaa actaaaagag atgacaatac caaactttat atctggtata
    41821 tttggagtta cagagccagc aatttatgga atattattgc ctttaaagaa accatttata
    41881 ataagttgta ttgctagtgg gattggaggc gctttctacg gattctttaa tcttagaaaa
    41941 tttataactg gaggtatggg aatatttgaa cttccagcaa tgattgaacc agatggggga
    42001 atgggtaact taatagtagc tctttctggc atagctatat caatggtcgt agcttttgta
    42061 ttaactatga ttttatataa agatgagaaa gtagaagagt ctaaaaaagt aagaaataag
    42121 gggaaagaag aaataaaaga agtcaagtct actaaattag aaagagaaat agtagcaagt
    42181 cctataaaag gtgaagtatt aaaattaagt gatatagagg atgcagcatt tgcatctggt
    42241 gtactaggtc aaggggtggc aataatacct agtgatggaa aagtagttgc tccagtagat
    42301 ggtgtagtta caaccttatt tcctagtcta catgctatag ggattctttc tgatacaggt
    42361 gttgaagtgc ttattcatat tggattaaat actattcaat tagaagggag aggttttgag
    42421 gcatgtataa aacaaggtga tagaattacg aaaggtcaaa ctatattaaa ctttgatgtt
    42481 gatgcaataa aagagttggg gtatagtact gtaactccaa ttgttattac aaattcatca
    42541 caatttttag atgtagtaga aacagaaagt aaaaatattg aattagaaga taatctaatt
    42601 acagtcttat tttagtaaaa attgaggcat tagcataagc tagtgctttg gttataattt
    42661 taggaggctt tgactatgag ttttaagaat gattttttat ggggaggagc tactgcggcc
    42721 aatcaatgtg aaggtggata caatgaagac gaaagaggat tggcaaatgt agatgtatgt
    42781 ccaacaggaa aagatagaac agcagttatt acagggaaat taaaaatgtt tgattttgat
    42841 gatgagcatt attatccagc taaaactggc attgatatgt atcataatta taaagaagat
    42901 ataaagttat ttgctgaaat gggatttaaa gtatatagaa tgagcattgc atggagtcga
    42961 atatttccaa aaggtgatga agaaacacca aatgaaaaag ggcttcaatt ttatgaaaat
    43021 atatttaagg aatgtaaaaa atataaaata gagcctttag tcactattac acactttgat
    43081 tgtccaatgc atttagttaa aaagtatggt gcatggcgta atcgaaaaat gataggtttc
    43141 tatgagaaat tatgtaatgt tatctttaga agatataaag gattagtgaa gtactggcta
    43201 acttttaatg aaataaatat gattttacat gctccattta tgggtgctgg tatttgcttt
    43261 gaagaaggtg aagatgttga aaagataaaa tatcaagctg ctcatcatga gcttgtagct
    43321 agtgcaattg caactaaaat agcacatgaa gttgattcaa ataacttagt tggatgtatg
    43381 tttgcagctg gaagtgtata tccttatagt tgtaatccta atgatgtatg ggaagctaca
    43441 aagttagata gagaaaatta cttctttgtg gatgtacaat ctaaaggtaa atatcctaac
    43501 tatgcgttaa agtatatgga gcaaaaaggt attacaccag aaatggaacc tggtgatatt
    43561 gaattattga ataaatatac agtagatttt atttcatttt catattacaa tagccgttgt
    43621 gttagaaccg atgaaaatgc agatgatatg gctgaaggaa acatatttac atctgctaaa
    43681 aatccatatc tttcatacag tcaatgggga tggccaattg acccattagg tttgagaatt
    43741 acactaaatc atgtatatga tagatatgaa aaaccactat ttattgtaga aaatggatta
    43801 ggtgctaaag atatagctga tgaaaatggt tatgtagaag atgattacag aattgattat
    43861 ctaagagaac atataaaagc tatgcatgat gcagtttcta tagatggggt cgatttatta
    43921 ggttatacta catgggcacc tattgattta gtaagtgctg gtacaggtga aatggaaaag
    43981 cgttatggat ttatatatgt agatagagat aatagtggta atggaagtct aagaagaatg
    44041 aaaaagaaaa gttttgaatg gtataagaaa gtaattgctt caaatggtga agatttatat
    44101 tagacaagaa atctatgtta aataagaaat ttgtattaaa taagaagagt ataaaaatta
    44161 ataataagta taatttttaa cttttttaac tatagaaaat caatacagaa ttattttaca
    44221 ttgtatttat gcgatagtat gattcacaaa taaaatttta gaaaataaaa ttgttaagaa
    44281 gtatgggaag taagtgcaat ttactttgta ataaaagatg aaaaaggcga gcttaggttt
    44341 taagcttgtc ttttttatta tgtataaact atgatacttt aaaattctat gaaaaattta
    44401 tttaatagag aaattaaaaa tttaatggta atcaaattct ttaccaatga atataaaaaa
    44461 tgtctacgtg ttataatagt ttaaactaat aaacgaaagg tagatgaatg aatatgaaat
    44521 accaacatat aatagaagtt gacaaagaac tttgcattgg atgtgggctt tgtaaaaatg
    44581 attgtccagt aaacaatata attatagaaa ataaaaagtc agtaattaaa aaacaagatt
    44641 gtctaatgtg tggacattgt gcagcaatat gtcccacaaa agctattacc ttgacaggat
    44701 ttgatgaacc tcctatagaa cttacaaata agtcaaagct agattcagat gaattactaa
    44761 tggcaattaa atctagaaga agtatacgta aatttaaaga caaagaagtt tcttcagaaa
    44821 ttgtaaagca aattattgag gcaggtaggt atacccctag tgctaaaaat tcacaagatg
    44881 tatcatatat tgttttagac aataaaaagt caatttatga aaacgaagca gtgaaatttt
    44941 ttagaaaaat aaaacctatt gcaaatatag ctattaaata ttcaaaagaa gttgagattg
    45001 acgataactt tttctttaag catgctccta ttgcaataat gataattaca aaagataaga
    45061 ttagtggttc acttgcagca tcaaatatgg cattaatggc agagtcttat ggtctaggtg
    45121 ttttatttag tggatatttt tcagatgtag caaataattc gccaaagtta aaaaagcttt
    45181 taggtctaaa acgcagtaat catgttctta caacattagt aattggatac ccagatgtta
    45241 aatatagacg tactgcacag aaagaagtag caactgttag atacttataa gagagggtgg
    45301 attttatgga aaaagaatgt caacaaagaa tgcaagaaat aacgtctaaa tttaaagaat
    45361 gtcgcaaagc tatctctgct atgggtgatg agactagaca attgatttta attgctctct
    45421 tagagagtga ttttaatggt atacgagtgg gagaaatcac aaaaaaaaca catctttctc
    45481 gtcctgctgt atctcatcat cttaagatat taaaagaagc agagattgtt aatttgcgta
    45541 gagaaggaac gaaaaattat tattatcttg attcaaaaaa atcacaatgg aagtcactaa
    45601 cagagctaat aaatcttata tttgttggaa tacaacatat tagtgaaaat gatataagaa
    45661 aaggtgatta aattatactt gatttaatac aaaaagattg atttaggaac taaaaagttc
    45721 actttgagac actatctttt gaactatacc catcttagga gacagttaaa atatgtaaaa
    45781 ctgtataaaa caatgggtat agttcatttt ataatggttt aaatattaag aatatattat
    45841 tctaaatagt atctttctct gttttgagtt ttatttttat actcaatagc ttcagtgggg
    45901 caaccacaaa tacatgccat acaatgagta cagctatttt tccaaactgg ctttttgttt
    45961 tttaaattaa tattatttaa aggacatagc tctacacatt ttccacagcc aatgcattta
    46021 tcagtataat gaaatccttt ggcactaata attgtcttat aaaaaactgt atttattata
    46081 ccacttttaa ttgtacctcc taagccacta ggagtaatag tttcaaattc attttcattg
    46141 cgtatatcag aaataatcct atatatttgt ttatctgctt ctttaatcat ttgttttgat
    46201 gtttctttgt ctgttgtaga aaataaagct atataattct ctggcatttt aatttctgcc
    46261 atacctttta attgccattc cttgtattta catagttttt gaatatagtt tatggatttt
    46321 gctgtatctc ccccacaagt cattacaaag taaactctgt tgtctcctag aaattttgtt
    46381 tcttttataa aatctgtaac cactattggc aatctccatg cataagtagg acatacgaat
    46441 atgaatggtt tatctgctga tattaattca tctgtttttt cctcttttat aagttgattt
    46501 agtgatatca gttcatcatt taattcttgt gcaattttac gagccacata tcggctatta
    46561 ccagtaccgc taaaatataa aatcataata atatctccct aactattttt tattttaact
    46621 cttaattttt tatttattat agtactttat tgatatattc tattcaaatg tatgtaaaat
    46681 ttagtagtta agaaaattat aacacattag taatttttat attcattggt aaagaatttg
    46741 attaccatta aatttagtaa caaaatatca actggatttt tatataagaa gagatagtaa
    46801 ttttcatgtg aaagattgta aatataaaga tgattttgaa gggcaataag aagataaaat
    46861 tgatagctta ataaaaaata tttaactttt atattaactg ttttaaatat tataattatc
    46921 tatcttgaat aatcaaccat agaagactgt atacaaagac aaagttgtgt acagtctttt
    46981 ttataaattt aatgtctata attaaataca ctattaaaat caataagtta ttatttcaaa
    47041 gtagtattat ccaaattttt atgatggtta atacaatttg ttagccattt tatagcacct
    47101 tgttccctga taatagctcc atcaagaact atataatcac caaaatcatt actatcaaga
    47161 ggaggaactt cactataacg ctccatttga ctgtacaaga acgtaattct ttcttggtgt
    47221 tgaagcaatt gatgctctag taaaataagc ctagtatcta tatctaaatt attagaaaaa
    47281 tacattctaa gacgaaaaat atccttaggg gttctttcca ttggctcatc cttttcaagc
    47341 catttcaaga actcatcttt acctttttct gtgattgtgt ataacttttt ctctaataca
    47401 tcaccactaa ttttaatatc atatacaata agcttttcat ttaccaattt ttttagttca
    47461 ggatatattt gactatgctt tgcattccaa aactcagcta attgaaaatt gaactctttt
    47521 acgatatcat aaccagtcat aggatttcta tttaataatc ctaaaattgc atactttaaa
    47581 gttcgcataa atacacctct ttctttaatt acatacttat tataacacga tatatttagt
    47641 ttgaattaat taatatagct atgttttaat aagaactttt aaattatgag gaacaaaaaa
    47701 taaataaaac tatatataaa aatgaaatta tgtaaatata aacatgtaag taattacatg
    47761 tttatattta catatagaaa aaattgtgat aatcttaact aagaaattct atttaataaa
    47821 tttatcgagg aggagagtaa tgaatttaac acaaaaaaga tggattatat taattgcaag
    47881 ttgtttcatc aatttatgta ttggttcaat atatgcgtgg agtgtatttg catcacctat
    47941 ggcagaacat ttaaatagtc ttgctggaac aacttttaca gctgctagtt tagcaattgt
    48001 atttacagtt acaaactcag ttggacctat tactatgatt acagggggaa tgataaatga
    48061 taaatttggt cctaaaaaag ttgtatttgt aggaggatta atttttggga taggtatgat
    48121 attggcaggt ttctcaaaag gattgcctat gttgatttta tcatatggga taataacagg
    48181 tcttggggtt ggcatggttt atggatgtac aataagtaat tcaattaaat tttttccaga
    48241 taaaagtgga ttagttggtg gtataacaac agcagcttat gggtttagtt cagtaataat
    48301 gcctccagtt gctaattgga taattaataa atatggagta acttctgcat ttaaatcaat
    48361 aggtttagta tttcttataa ttgtatgtgt ttcttctttc tttatcaaaa aatgtccagc
    48421 agatttcaca ccagaaggat gggtaccacc agagaaaaaa ggaaaagtaa gagttgttat
    48481 taataaaaat tggaaagaaa tgctttcaac acctatattt tatctaatga ttataatatt
    48541 aacttgtgga gctttctatg gattaatgtg tgtgtcatta gcatcttctc tagcaacaaa
    48601 tatgattggg atgacaagtt cagattcagc aatagtggtt tcaattttag ccttgtttaa
    48661 tacattaggc cgtattgttg caggatatat atcagataaa attggtagaa taaatacttt
    48721 atcaggtgca ttagttattt caatttttgg tttattatgt ttgttattct caagagaagg
    48781 agatgtagca acattctata ttggaataat aattataggt atatgttttg gttcatttat
    48841 gggaattttc ccaggattta cagtagataa atttggacct aaaaataata gtgtaaatta
    48901 tggaatcatg tttattggtt ttgcttttgc aggatatatt ggacctgcag tgatgaaaaa
    48961 tgtatattct gtagatggca attatcaaag ggctttcatt atagctataa ttatagcttt
    49021 aataggtttt atattaacat ttttatataa atatataaat aaaatacaaa atttaaagat
    49081 agaaaattta ataaagggag atataaaaaa tggaaagaaa atatccaaat ctatgtaagc
    49141 caattaaaat tggaaatgta acattcaaaa acagaatgtt ttcagcacct atggggggaa
    49201 cagacataac agcagattgt acaattggct caaaatcaac agccttttac gaattaagag
    49261 caaaaggtgg agcaggtgca gttacaatta gtgaatgtat ggttcatcca gaaacagatg
    49321 gttcacatgc atatcatcta gacttaaaaa tagttgattc cttagcaagt tttacttata
    49381 cagcagatgc aattcgccgt catggagcaa taccaagtgt agaactatct cattcaggac
    49441 aatattcagg aacttattta gttgacaaag ataagaagcg aggattatca caatggggag
    49501 taagtcctag tgttcgtcct gatggattag agataaaaga acttacagaa gaaataattg
    49561 ctgaaatagt agagtcatat ggaaatgttg cagcattggc taagagagca gggtttgaga
    49621 tgattatgat tcatggtgga catggctggc taatcaatca attcttatca ccttacttta
    49681 ataaaagaac tgacaaatat ggtggttctt tagaaaacag agttcgtttt gctaaagaag
    49741 ttttagatag tgttcgtaaa gcagtaggtc caggatttcc aatagagttt aggatgagtg
    49801 gttctgaatt atttgaggga gggtatgatt tagattatgg aacagaaatt gctaaattat
    49861 tggaatcaag agtagattta cttcatgtat cagcaggtac ataccaaaga gggtttgcag
    49921 taacacatcc ttctatgttc ttagaacatg gatgtaacgt atatcttgca gaagaaatta
    49981 aaaaacatgt aaatattcca gttgctacta taggagcatt aaatgaccca gaaatgatgg
    50041 aagagataat tgctagtgga aaagcagatg ttatttacat ggctcgtgca ttactagctg
    50101 accacgaatt accaagaaaa gttatgagta atcaagatga aaaaatagtg aaatgcctaa
    50161 gatgcttcac ttgtatggca gaacgtgcta ccacttctac aagacgctgc actgttaatc
    50221 cacttattgg acgtgaatta gatggaactg aagttgtttc agtattaaaa cctaaaaaag
    50281 tattaatagc aggtggtgga ccaggaggat tgcaagcagc cattacagct gtaaagcgtg
    50341 gacataaagt aatactttgt gaaaaaacta atgaattagg tggaatttta aagggagaac
    50401 aagcacttcc atttaagtat gaaatgtatg aattaggaaa tacttttgga aaaatagcaa
    50461 aagatttagg tgttgaagta cgtttaaata caacagttac aaaagaatat gttgaaaatg
    50521 aaaatgtcga tgcattaatt atagcagtag ggtctgaacc tcttgttcca ccaatagagg
    50581 gtcttgatgg agaaaatgta gtaatagtta atgattatta cgtagaaaaa gaaaaagtca
    50641 ctgacgaagt aatagtttta ggtggaggat tagcaggatg tgaggctgca attcacttag
    50701 ctcaagaagg gaagactgtt cacttagtag agatgagagc agaacttgcc ccagatgcaa
    50761 atataaggca tcgtccaata ttattagaag aaatagaaag acaaggtata tatgtatata
    50821 cagaacataa gggtttaagt gtaacaacag aaggtgtagt atgtatgaat aaatctggga
    50881 ataaaataaa tattccagga acctcagtaa tatgtgcact tggacaaaaa ccaagaagag
    50941 aagtggtaga cactttactt gattctgctc catatgttgc tcaaattgga gactgtgttc
    51001 gtgcatctac aataacaaat gcagtatacc aagggcatca tgctgcgcta gatatatagt
    51061 taaaaagacg tagatagtat tgttttatta taaaaaagga gtgtctcaaa atgaactttt
    51121 tagttcatga gacacttttt tacatgaaat taaatatatt tttatcattt caacaatgaa
    51181 aaaagattat ctttattttg agacagcact tttgttatta tgattttaat tcttattgca
    51241 agttttcatt tgattgatga gtaaaacttt ttaagatgta gaagtattta acaatgtaaa
    51301 tgaccctaac ttaaatactt tagcgaaggt tgacagattt gtgtttgctt ttatctatta
    51361 taacttaagg aaacatgtta cctgaacaat aaatttatat aataaaagta tataaatata
    51421 tatatgaatg ttaagattag ttgatagaat ttaaataata aatccaatat tataaacata
    51481 ggaggtatga aaaatatgat taatgagaat ttaaaaagtc taagaaaaat ccaccagtat
    51541 acacaagaag aattagctga aaaacttaat gtttctagac aatcaatagc aaaatgggaa
    51601 agtggagttt cccaaacaaa aggatattac tgaaataacc tgtgtttacc tgcttgtaga
    51661 gaaaagaata ttgctattaa gccagagata ctacataaat gtgttggtat ctctttttcg
    51721 ttaatgcaac acagtaaatt atttcatttt cctaattatt ttagactgat aagtaacttt
    51781 ttaaatgaag aaaagaaatg acaatactta aaggagcatg gtatacttaa aggagcatgg
    51841 tatacttaaa ggagaatttc attaaggagg aaaaagagaa tgtttaatct aatagaaatg
    51901 ttatttccta taatgtttat actgattttt ataataattg ttttcacttt tgtgaaagga
    51961 atagctactt ggtttaaaaa caataattct cctcgcttaa ctgtgtcagc aagaatagta
    52021 gcaaaacgtc agaataccac tcataacaat caaccaaacg ctggtgatat atcaggagca
    52081 catggatttc atacaatttc cagcacctcg tattatgtga catttcaagt agatagtggt
    52141 gatagaatag agctgtctgt atctggctca gagtatggag tgcttgcaga gggagataaa
    52201 ggacagctga cattccaagg cacaagatat ttaacatttg atagggaaaa ttgaatttag
    52261 aggtgcatta tgaataagtt tttgagtcag ataaggcgta tagagaatga aatatctatt
    52321 actaggaaaa ttataaatac aatatttata ctgtgttttg gaatagtttt aggaactttt
    52381 gcaaaatttt tagatactac agcaagcaat actttaccat ttatatttga atatttagat
    52441 attagtaatt tttttggtcg ttttgctata tggttattga ttgctttgta cattgcaatt
    52501 tatagtcatt cttccataag agcatcatta aatgtgttag tatttttcat tggaatggtt
    52561 tcaagttatt acctatattc atattttgtt gctggatttt ttccaaaaaa ttatgcaatg
    52621 atttggcttg gttttactgt catttctcca ttgttagctt ttatttgttg gtatgctaag
    52681 gggaaaagca aaatatcttt tatactttca gtaataataa ttgcaatttt atttaatttt
    52741 acatttattt atggttggat ttattttgat gtgtattcaa ttttagaagt gatagtcttt
    52801 ggttgtgcat taatagcttt aaaacgtaac acctttaggg agacaacgta tatgatattg
    52861 agtgcagttg ttattgctgt tatacttaat atgttagttc catttcattt tggttaggca
    52921 gattttaaga ttattataga tagaatataa atttcacgaa ccgccgaagc gatccgccag
    52981 cggtggcggt cgtaagacat atcgccacgc cagcttgctg gcgaggtggc ggttcacttt
    53041 ggtggtttgg cgagcctgcg agctttctaa gcccccgtta tctaacaggg ggggactatt
    53101 acaaaagaca agagcaaaaa caaatataaa actgctgata tgcaacgatt tataaggttg
    53161 taagaactta tttcacttca caccctattc tttctacccg acaggtctaa aacagcatat
    53221 caatagaaaa taaatataag atacaaggtg tatgctccta tgagtatatg cctttttttg
    53281 attggaggaa tgaagcatga atgatatgaa atttattgaa acattaaagc aaaagagaaa
    53341 tgtctgtgat tattcgcaat cacgactggc acaggaacta caaatcaaca ggcagaactt
    53401 aaatgaaatt gaaaacggaa aaacaaaagc cagtaaagaa atgaaacata tactcttaca
    53461 ttatcttgat tattgtaatt gtacacagcc tttcacttta acgattgact atctgcgtgt
    53521 tcgttttcct accacagacg cattggaaat tataaaaaat gtgctggcaa tgaaaagcga
    53581 atattttata catgaagatt acggaatgta tggttatgaa gaacagtata tctatgggga
    53641 tattagtgta aatgcttcta aagatagttc tatgggtgtt ttattggaat taagaggtat
    53701 ggggtgtcgg aacttagaat atgttttaca ggtaagaggg atagactggt attgcttttt
    53761 aagatgttgt atagattatc aaggtgtttt taaacgcata gatttagcag tcaatgatat
    53821 gggcggattg ctggatatag aaattctaag ggaacgttat tatgctaaca aggtatggaa
    53881 acgttcaaga acccatgaag cagtagacag cggaaaatta tcgggtacac atggagatac
    53941 tgcaaaaact ttttatatcg gttcaaagaa tagttctatc tacttttgct tgtatgaaaa
    54001 agaaaaggaa caaaaaagca agggtataaa aacagatatt aagaaccgct ttgaaattcg
    54061 tttaaaaaat ggaaaagcat gacaaacggt agagcaactt gttttttcaa gaaatcccga
    54121 acagaccata gcaagcctta ttctcacaca gatagatttt cccgattata ttttatggga
    54181 tatattttta gataatgtaa cgacctcact tccgtttatt atgacacctg ttgctgtcaa
    54241 tatggataaa acaaaacgct ggctagaaag acaggtcatg ccctctttat tgatgataaa
    54301 agagattgaa aagaaaacag gagcaaatta tctggaagaa atcgacaggc atacaaggct
    54361 aacagaaaag cagtaattaa agattaaaca aatgacaaca gacatagcag atatgattga
    54421 gaaagatacc gctgttccac aagggaatga cggtattttt taatttcttc aaaaaaactg
    54481 caacaaaatg actgcttgtg tacagatatg gtgcgaggaa aggaaatcta actttttttg
    54541 aaaacaggtc attaaatcgg tggttgctgt ccctatatga tgtgaaagaa gaaacgattt
    54601 ttaatttcaa cttaacattt gacagttttc attccctata tggagcaaag aaaatctttt
    54661 attccatagt tggcagttac ggtgttgcat gggtagttag ggtgtgaaaa gaaaaacaga
    54721 tttttttcat caccaactta gcaaactgat acttgctttc cctatatggt gcaggaaaag
    54781 agagtttaac tattttcatt tcaacttagc aactggacgt ttgctgtaca gatatgtagt
    54841 gaaaagagaa aaagttttga atattggtta cgcttcggct cttttccaac gcggtatata
    54901 ggaaagacga ttttcttctt tcatgttctt tgacaactga ataaagcaat tcaatacgtt
    54961 tgacagacag cgatccattg aagcagatac gccatgacct tttccctgca aaagcgagcg
    55021 aaccctattt gtgttcctgt aaaagacttg tcctctttta tcgccatgac cttttctgtc
    55081 tgataatgat actcccgtac agccacagct tgaacgttca gagcgtcgca cgcaatgggt
    55141 acggctacat aagaacttat gcagaggtgg aattcctgtg ggctatgaca aatgccgttg
    55201 aattgcttag aaaaaagatt atggaaaggg ggtatgtgtt attgctgata ttgtaaaaac
    55261 aatgcaagaa aagacaaata ataagcgtag cattggcaac agaggaaaaa caaagattgt
    55321 tgtaaaagag catttttccg aaaagggaaa gacaatggag gaacttctga ctgatgttat
    55381 gctggaaaaa gcaaagcaga caatcgcata aaattggtgc agttgtaaga catagattga
    55441 atggcaaaaa gtacccgtgt tatactttac ttgcaagcag gtattgtaaa cacgggttag
    55501 ttataaagga ggataactga caatgaaaca acagatttac aatactgcac tttatcttag
    55561 gttaagccga gatgatgaat tacagggcga aagttccagc attaccacac aaagaagtat
    55621 gttgcgtcta tatgcaaaag aacatcattt gaatgtgatt gatgaatata ttgatgacgg
    55681 ctggtcggga acaaattttg aaagaccgag ttttcaaaga atgattgagg atatagaggc
    55741 aggaaaaatc aactgtgttg taacgaaaga cctttcccga cttggcagga actatattat
    55801 gacaggacaa tatacagaat tgtattttcc cagccataat gtccgttaca tagcgattga
    55861 cgacggtgta gacagcgaga aaggcgaaag tgagattgca ccatttaaga acatcatcaa
    55921 tgaatgggtg gcaagagata caagccgtaa agtgaaatcg gcatttaaga cgaaatttgc
    55981 agagggtgct cattatggtg cttatgctcc attaggatat aagaaacacc ctgacatcaa
    56041 aggaaaactg ctggttgatg atgaaacaaa atggattgtt gaaaaaatct tttccctagc
    56101 ctatcaaggt tatggtagtg ccaaaatcac aaaggtactg cgagaggaaa aagttccgac
    56161 agcgtcttgg ctgaatttta caaggtacgg tacttttgca catatctttg agggaaagcc
    56221 cgaaagcaaa cgttatgagt ggacgattgc tcatgtcaag gcaatcttaa aaagtgaggt
    56281 ttatataggc aacagcgttc acaatatgca gtctacggtt tcattcaaga gcaagaagaa
    56341 agtgcgtaag cccgaaagtg aatggtttcg agtggaaaat acccatgaac cgattattga
    56401 caaagaagtg ttctatcgtg tgcaggaaca gataaaatca agacgtagac agacaaagga
    56461 aaaagcaaca ccgatatttg cagggcttgt caagtgtgcg gattgtggct ggtctatgcg
    56521 gtttgcaacg aatacggcaa ataaaacgcc ttacagttat tatgcttgca gttactacgg
    56581 acagtttggc aaaggtactt gttctatgca ctatatccgt tatgatgtgt tgtatcaagc
    56641 cgtattgaaa cgattgcagt attgggctaa ggcagtacag caggacgaag aaaaggtgct
    56701 gaacaagata cagaaagcag gcaatgcaga gcgaatacgg gaaaagaaga aaaaggcaag
    56761 tgcctttaag aaagccgaga accgacaaaa tgaaattgac cgtttgtttg cgaaaatgta
    56821 tgaagataga gcctgtgaga agataacaga gcgaaatttt gtgatgttgt ctagcaagta
    56881 ccaaaaagaa caaatagaac tggaacagca gataaccaac ctaagagaag aattaagtaa
    56941 aatggaacag gatatgatag gtgctgaaaa gtggattgag ttaatcaagg agtattccgt
    57001 accaaaggaa ctgacagcac cgttattaaa tgcaatgata gaaaaaatcc ttattcatga
    57061 agcaataacg aatgaggata acgaaagaat acaggaaata gagatatatt accgatttat
    57121 tggaaaagta gactgataaa gagggttcat atctttaact aagggaaact ggagaatcta
    57181 ttcctgatat aggtagttgc attaaacttg caaaattgta caaggtcaaa ctagatgact
    57241 tagttaatca ttcggaagaa aaaacaggta ttatagtacc tcctaaagga aagtttttct
    57301 ttggagcagt agtagttggt gaacgtggtc agattgtcat tccaaaagaa gcaagagaag
    57361 tatttaatat aaatgcagga gataaattat tggtacttgg agatgaggaa agaggattag
    57421 gaattgttca tcaacgtgat ttgataaatt ttataggtca tatgggagta gtacgtaaag
    57481 aagaatgatt ttaaaaaatt ataaaaggag gtatgaaata tgagtaaaat agtatttttt
    57541 agcattcttg catatggtca tactaatcct actattgaag tagttcgtga attagtggat
    57601 agaggaaatg aggcattgta ttattctttt aatgaattta aagataaaat tgaaggtgct
    57661 ggagcaaaat ttatttgttg tgataaatac cttccagaat tactccctgg agatgagaaa
    57721 aaaattggta aggattttcc tggattaatt gagatgatag tagatactac tatttcttta
    57781 gatgaaaaag tttgtaggga acttaaagat tttaatccag attgcattgt atcagattca
    57841 ttaagttttt ggggaaagtt atttgcacaa aaacttaata ttccatatgt atgctctaca
    57901 acaacttttg catttaataa acatacagca aagttgatga aacaaaactt tatagaaatt
    57961 atacgtatga tttttggtgt aagacgcatt aataaaaaaa taaagctttt acaaagaaaa
    58021 gggtatgaag taaaaaattt tatttctata gtttctaatg ataatgatac ggataccatt
    58081 gtatatacat caaaagaatt tcaaccaatg gtagaaacct tctctagtaa gtattcattt
    58141 gtaggtccat cagtatcaaa gttgattatt aaacctaaag agagaaaaag aaagttaata
    58201 tatatttcgc ttggtacaat taataataaa aatgttagct tttataaaaa ctgtataaat
    58261 gcatttaaag attctgatgt tgatgtgatt atgtctgttg gtagaagtac tgatattaaa
    58321 agtttaggaa atataccaaa taattttgag gttaaaaata gtgttgaaca gattgctata
    58381 cttcaaaaaa ctgatgtgtt tattactcat tctgggatga atagtgttaa tgaaagttta
    58441 tattatggag tacccatggt attatttcct caacattcgg agcagagaat ggtagctaag
    58501 agagttgttc atttgggagc aggaattatg ttaaaagagg ataagtccga aagtattaaa
    58561 aaagcagtat ttcaagttat aaatgacaat gaatataaag aaaatgcaac taaactatca
    58621 aaaagctttt ataatgcagg aggctcaaaa aaagcagcag atgtaatatt acagattata
    58681 tgtaatagta gacaagttga catataatag atttgttaaa aatatatata catacatgca
    58741 atttaatcaa agtactgaca gtggggtctt ttaacctacc agttggggca tatatattga
    58801 tgctaaatat gagggatgtt atattttaat aaaaaagata acatcctttt cttagtgtgt
    58861 tatatcaagt tttaaataat aaatgaagga ggattaatat gaaaaaatat aaagttattt
    58921 ttatagtatt aattataggt attataagtg taacagggtt tgttgtatat aaaaactgca
    58981 ttaaaccatg gaaagatgct gaaacatata ttgataagta tatggtaaaa caagatattt
    59041 caaaagataa tataaaaagt attacaaaag aaaaagccaa gaaggcaagt tacgaaggaa
    59101 tactatacaa agtgtattac aaagatgacc ctcgatatga gtatcaatat ttttatagtg
    59161 ataattatca tgctctatat gtaaataaag taatgttaca aatttatgat gtggaaaata
    59221 ataataaact tttaagaagt aatgaggaat taaaaagtgt aaagtatcca ccaatatatc
    59281 ttaaatataa gccagataaa tgatttatga caaaatagaa tgatttttat taaaatttat
    59341 ttaaaaatat cactagagtg tttaaataaa actaaattta agtatttata tattagtata
    59401 tcttactagt gtttaaacaa aattaaattt aagtatttat atattagtat atcttactag
    59461 tgtttaaata aaactaaatt taagtattta tatattagta tatcttacta gcatttaaat
    59521 aaaactaaat ttgaagcttt acctattaat atatcttaat agtgattaaa taaagctaaa
    59581 cttaagaatt tatttattaa catacagttc attatattta aaatcattac tatgataatt
    59641 cataatagta aaatagataa tggttcagac aatattgtaa atattagtga cagtaaaata
    59701 gtatcaattt agtatataaa ctttgccaga taatcgcata acagagcttg tagttataga
    59761 ataaaaaaat atctaggaaa ccgttgacag atttatatgg atagtataac atatagaata
    59821 tgaaattaaa caaaaaagaa ttttaattat ggcgacgtag tcataatttt gagtatgtta
    59881 ctgattagca ggcagaactc aagtatatat gtgaaaaata gagggatact ctatacatat
    59941 atgcttgagt tctttttatt gaaaggagga atatatgaaa ataattcaga ttttaaataa
    60001 taatgtagcc ttagtaaaaa gaggtaaaaa tgaaattatt gtatttgtta aaggaattgg
    60061 ctttaaaaaa agagtgggac aagtaataaa tgaaaatgaa atagagagaa catatatact
    60121 agattcatac gatatgctag aacactttag ttatctacta caaaactcag actccaataa
    60181 tatagttctt attaatgaaa taattgaata tggtgagaaa gctttaaata taaagtcaag
    60241 tgattatcta agcttaacct tactagacca tttagagttt ttacttaaaa gatgtgaaaa
    60301 gaatcaattt ataaaaagtc ctttggtatg gaatgttaaa agattttatc caaagcattt
    60361 tgaaattgga atgcatgcac taaaattaat tgatgatagt aagggaatta atcttcctga
    60421 tgatgaggca gtatcaatag cacttcattt tgtaaatatg gaggtaaata aagagtctca
    60481 tgatagtaca atcgtagagt tgagaacttt agcagatata gtttctataa taaaatatca
    60541 ttttaatgta gagctagatg aaacttcaac aaattatatg agatttacta ctcatctaca
    60601 gtactttatc caaagaatta tgtcagatga agcttcaata gatgaagata attctataga
    60661 tttatataaa caagtaagtc aactttatcc aaagtcattt ggaagtgttc aaaagataag
    60721 aaaatatata aaatcacaat ttaatgtcga tatatctata agtgaagaaa cttatttaat
    60781 gttgcatata aatagggtga ctcaaagact ggaggcaaaa tcagatgaaa tataaagatt
    60841 taaatgaaaa tataataaaa cttatagggg gaaaagaaaa tataaagtcg gtagcgcatt
    60901 gtgttactcg tttaagactt actttaaatg atagaagtat cgctcaaaca gaagaaatta
    60961 aaaaattaaa aggagtaatt gatgtagttt ctaatgatgt tgcttatcaa attataatag
    61021 gtactcatgt tgtagatgta tataacgagt ttatgtctat gataggttta agttcaagtg
    61081 aatcaagtat aaaaagtgaa agaaaaaagg gaattagagg tatcaaaggt atatttaatt
    61141 ccatctttgt ggtagtctca gagactatga cttcagtaat tgaagtacta cttgcagctg
    61201 gtatacttgc aagtatatta gcacttttaa atatgtctgg catacttcag agtgatagtc
    61261 ctacatatca aatattagat acattaagaa gtgctacatt tcacttctta ccagtattaa
    61321 ttgcaatagc atcagcaaaa agacttaatg taaatcccta tatagcagta gtgttagcag
    61381 ttacgttatt atcttcatca atagatggtg tagaaggatt aagtttattt ggtataaatt
    61441 tacaggatac aacgtatgca aacagtttta ttccaatact tttaggagta tgggcaatgg
    61501 gaattataat tgaaggtttg aaaaaaatat tacctaaagc actacactat tttttagttc
    61561 cagtgttatc tttaataata actctatcag ttacattaac tgtatttgga cctattggta
    61621 tgtggattgg tgatggatta aactatgcat gtatgttttt aattgataca ttgggtaatt
    61681 ggagtgttgt tgcactgtat gcagctttac aaccactctt aatagttttt ggtgcagcaa
    61741 actttactat gcctatatct ttaaattctg tgacaacatt ggggtatgat ccaattttta
    61801 tgggcgctgc aacaatatct gatattgcag tttgtggtgc aatgtttgga tatttcttaa
    61861 aaactaggaa taaagaacaa aaacaattat ttgggacagt aagttttagt gcacttatgg
    61921 gagttacaga accttcagtg tttggtgtgt ttatgaaata tagaagacca tttgtagcag
    61981 taatgatagg tggaggtata ggtggtttaa tagcaggttt agctcaagtt aaaacatatg
    62041 gaatggtttg gggattagct gcattaccaa catatcttgt tggaggagag gcatctaact
    62101 ttacatttat gataataagt gtagtagtat catttgtagc agcaacagca gcttcctatt
    62161 tactaggaat accttcagat gaaaaagaag aagttaaggg tgataatgaa aaagaattag
    62221 aactaataat caacgagaac aattcaagaa ctattagtat tggaaatgtt gcaaaaggtc
    62281 aggtaattgc acttggggaa gttaatgaca aagcattttc ctctggagca ttaggtaaag
    62341 gggttggagt tatacctagt gaatcaaaat caactgttat atctcctgta gatggaacta
    62401 taactatagt atttccaact aaacatgcat atggtatagt gactgatgaa ggattagaaa
    62461 tattaattca tattggtata gatactgtaa acttagatgg aaaattcttt gaaagtcttg
    62521 taacacaaaa tcaaagggtt aaaaaaggag atgctttagc agtatttgaa tctgataaaa
    62581 ttatagagga aggctttgat tctactataa taactgtagt tacaaatact agcgattatt
    62641 tagatgtaat ctcatcaaat gatgaatcag aagaattatt aactgtaata gtataaattt
    62701 taggagggaa aattcatgaa tattaaagat acatttttct ggggaggaag tattgcagcc
    62761 catcaatgtg aaggttcatg ggatagtgat aacaaaggac ctgcaattat ggattttgta
    62821 actaagggct cttatgaaac gccaagagta attactgata aaatagaaga aaaattggat
    62881 tatccatctc ataatggaat agatttttat aatagatata aagaagatat agctttattt
    62941 aaagaaatgg gatttagtgc attaagaata tctatagatt ggtcaagaat ttttccaaat
    63001 ggagatgatg aaaatcctaa tgaattaggg attaaatact atgaaggtct gatagataca
    63061 ttaatagaaa ataatataga acctattgta acactatatc attttgaatt acctatgaat
    63121 ttagtacata aatatggttc atggaataac agaaaactta tagatttgta tttaaagtac
    63181 agtgagactg taataagaag atttgatgat aaggtaaagt actggattac atttaatgag
    63241 atgaaccata ttgaccctca aacagagcac tcggatattt ttacttatat gatagcaggt
    63301 attaagtata gtgaaataga aaataagatt caaacattgg caaatgtagg gtataatatg
    63361 actttagcgg gtgtaaaggt tgcaaagttg gctagagaaa tcaatcccaa caataaagtt
    63421 ggatgtgtat ttggactaaa tccaatttat ccatacaatt gtaatcctag taatgtgtta
    63481 aatgcatttt tagataatga tcgtgattat tatcaaattg atgcaatgtg caatgggaag
    63541 tttccccaat ataaattaaa agaatatgaa aaaaataata taactattga agtgactgat
    63601 gaagacaaaa aagcatttaa agaaggtaag ttagatttta taggtcttaa ttattatttt
    63661 tcaagtgtat ctactccaaa agaaaattta tcaggtgata aatctttatt tggtgggatt
    63721 caaaatccat atttggaaca aagtaagtgg ggatgggcaa tagaccctat aggtttaaga
    63781 tttaccttga actatattta cagaaagtat caattaccta tcttaattac agaaaatggt
    63841 ttaggggcat atgataaaat cgaagaagat ggaactataa atgatgatta tagaattgaa
    63901 tatttaagta agcatctatc tcaaatgaag tctgcaattg aagaggataa tgttgaatgt
    63961 tttggatatt tgatgtgggg accaattgat ttagtcagtg caactacagg tcagatgagt
    64021 aagagatatg gatttatata tgttgactta gatgatgaag gcaaaggaag ttttaagaga
    64081 tataagaaaa aatcatttga ttggtacaaa gaagtaataa aatctaatgg agaagtttta
    64141 gatttttcta cggatatagt agtagggtag taataagata aatagaagtt aggaactaat
    64201 gttaattagt gtctagtaaa gcatttaaaa tagagtatag ggtctttaaa gtaaagtgtg
    64261 tattcttatt aaaagtaatg gcaactaaaa ttactataaa aaggagaata cacatttttt
    64321 atgtttatac ttaagtaaat atttagacat attcatagta taatttactc attatataaa
    64381 aatagtataa tttactcatt atataaaaat agtatgattt actcactata taactttata
    64441 aattttctag aaaaatgtca gaatatattg acaaaaaaaa gatttgaaat tataatctat
    64501 attgagaata gtttgacaat ataaaaacaa gtatttttac aaatagtgaa attattttta
    64561 ttgtcaattt aagaataatt taggactact ataaagatga aggtatagat gtcattatat
    64621 gataaatcat acttgtatag aaagaatttt aaagtatgct tatcattgat ttaatataat
    64681 aaataatttt tgtttctagt aatagttcat aggaataaga tatctaaatt cgcttagaaa
    64741 tagtctaatt tacaaaggag gggatgcact agtagataaa atttttatat aaagaagact
    64801 taaagtggag tatattctga taatattggt ttaatggtta tattattatt tcgttttaga
    64861 tattttaaga ataatttaag acgtttgtaa aaatgtattc tatatctaat atttaaataa
    64921 atataagtct tccaacatgt atactaagat agaaagtagt tgaagtacaa ttctaacttg
    64981 taaaattatg tagaaagtaa aaatcaaaaa gaaatctagt aagttgataa ttatagttaa
    65041 tatttagaga gttaactcta gttatattta tttagatatt ttaggaataa tttaagacgt
    65101 atataatatc atcaaaaaat atcaagctat accatatgta gttaagaata actgcataat
    65161 atacatttta taattattgt tttattgata aaaaattatt atatttagga ggaaacaaca
    65221 atggaaaatt tttggaatcc acttacttgc tttactgtat gtgtaatgat ttatgctttt
    65281 agtgagtttt tatctaagaa aacaaaaggt gcaatttcaa cattgttatt tgtatgtatt
    65341 atatttttac taggattttg gacaaatgtt ttaccaaaag acattacagg agcatcaggg
    65401 atattagctg caatgagcaa ctttggtata gctttattaa taactaactt aggaacactt
    65461 ataaatcttg aagacttatg tcatgaatgg aaaacggttg taattgcatt agtaggtatt
    65521 gtaggaatag gggttggctg tttaacagtg ggtagtatgt tatttggtag agagtatgct
    65581 ttaatagcag cacctccaat agcaggttct actgttgctg gtattatcgt aacaactgtt
    65641 gcagaagctg caaatagacc tgaacttgct gcatttgtaa ttctagtatt atcatttcaa
    65701 aagttctttg gcattccgat aactacatat tgtataaata aagaattaaa atttaaaaga
    65761 gataacgggg attttttgaa agatgagtca aaaagtaatt ttagacttcc aagtatgaga
    65821 atttttaaag aagatttagg taaaaaatca tctactctag tgtatcttgc aaagctttca
    65881 tttgttgcta tgattggtaa ttttgtagga ttggctactt taataccagg atttacccct
    65941 gcaaactatt atttaaatcc taatatagca tgtttgttag tagggttgat ttttacacga
    66001 ataggttttt tagaaaaagg aattttagat aaatctcaat ctaatggaat tataatgttt
    66061 ggttgtatgt tgatgttacc tggaggactt gctaaggtaa ctccaacagc attgtttggg
    66121 atgattgttc caactatagg aatacttgtt gtaggttctg tatttataat attatttact
    66181 gcaattgtag gaaaactatt gggatattct ccaagaatgt cagctgcaat tggtgtaact
    66241 tgtatgctag cttatcctgc aacacagata atttccaacg aaggtattga tgctatggaa
    66301 ggaactgaag aagaaaaaca aagggcaaca gattatttat taccaaagat gattatagga
    66361 ggatttgtta ctgtaaccat tgcatcagtg gcatttgcta gtataatagg tccaattata
    66421 tttggttgat agtaaatata cttataggag gaataagaaa tgataggaag tatatctata
    66481 aatgagatag ataaaaaaag attcaaactt gatgatttaa gtaagaaaat atgggaaaac
    66541 ccagaaaaag catttaaaga atttaaagca tgtgaaaata cagcaaactt tctaagaagt
    66601 gaaggatttg atgtggaagt aggtgtagga ggtttagcca cggctattag agctagtttt
    66661 ggttcaggta aaccagttat aggttttatg ggagaatttg atgcattacc tggtttaaat
    66721 caaaaagttt caacaaagca agaagcattt gaattgggtg catatggtca tggatgtggg
    66781 cataatttat tatgtacagc acatgtaggg gcagtagtag gacttaaaag agagatgcta
    66841 gaaaataact taagtgggac tatagtattt tatgcatgtc caggagaaga acaattaaca
    66901 ggtaaaggat ttatggctag aggtggagca tttgaagggt tagacttagc tataaatttt
    66961 catccaaata aaattagtga agctacaatt ggtacttcaa cagctgttaa ctctgtaaaa
    67021 tttcacttta agggaaagac tgcacatgca ggctcagacc ctcaaaatgg aagaagtgca
    67081 ctagatgctg tggaacttac taatgtggga gctaattatt tgagagaaca tgttacttct
    67141 gatgtaagga ttcattatac aattacagat ggaggagtag cacccaacat agttcctgat
    67201 aaagcatcag tatggtatta tacaagagct ttaagtagag aagctgtaga aagtacatat
    67261 gaaagacttg taaaggtagc aaaaggagct gcaatgatga ctgaaactga agttgaagta
    67321 gagtttttag gaggttgtta taatacttta aataatcatg ttttagcaaa tcttgtatca
    67381 gaatgtatga atgagattaa acaagagcct tggactcgag aggaattgga ttttgcagct
    67441 gaattagata gacaaagccc acaacaatat aaggctatga taagtaaata taatttgcca
    67501 gaaggaactc atctatatta tggtggagga aatgttacaa actttaatag ttatggctct
    67561 actgatattg gagatgtaat gcatatagtt ccgacagcat acttttttac agggtgtacg
    67621 aatctaggtg caccaggtca tagctggcag tttacatctt gtgcaggaag ttctatagga
    67681 gaaaaaggta tgatatatgc atcaaaaatc atggctatgt ttggagccaa aatattaaat
    67741 aatccagaga tagctaaaaa ggcaaaagaa gagtttgata aatctatgaa tggtaaaaca
    67801 tataaatgtc ctattccaga tgatattcca actccttaaa aagacatgaa gtttaatata
    67861 taaaattata atttttatat cagcatcatt tcattactaa aagaaagtga gattttgctg
    67921 actatctgat taggaggaag gaatatgaaa aattttttta aagaagcgca gtcaatagaa
    67981 ggggaaatta ttagatggag aagatattta catgaaaatc ccgaaattgg ttgcaatcta
    68041 ccgaaaacag taacctttgt taccagtact ttagaaaaaa tgggatattc tccgaaattg
    68101 acgtctaata atggaatagt agctgtttta gacagtgaaa atggtggaaa gaccttatta
    68161 ttaagggcag atatggatgc acttcctatt atggaggaga cggatttacc ttttaaaagt
    68221 aagaataaag atgcatctca tagttgtgga cacgataatc acacagcaat gctcttagga
    68281 gcagctaaaa tacttatgga taataagcac ttacttaaag gtagagtaaa gtttgtattt
    68341 gaaccagatg aagagagtac cagaggtgca aaatcaatga ttgatgatgg tatattagaa
    68401 aatcctcagg tcgatgcagc tatggcattt cacagtatgg tgggtaaatt tcttaacaca
    68461 ggtcaagtag cttattcacg tggtccagct atggcatctg cagatatatt tgaaataaca
    68521 gtagaaggaa aagcaactca tggagcaagc cctgaatttg gagtggaccc aataaacata
    68581 atgtcgcata tacaaatagc attaaacact atactttcaa gagaaaaacc tcagaaagag
    68641 cctgtagttt taactattgg tatgtttaat gcaggaaacg taccaaatgc tataccaaat
    68701 aaagcatcta tgtcaggaac tttaagaaca tttgaccaat ttgttagaga aaaattaaaa
    68761 aatagaatta ttgaaatatc tacaggaata gctaaatcat ttggaggaaa tgctaaagtg
    68821 gaatttaaaa tggggactcc cgcagttata aatgatttgg atgtaggaga tgagattgta
    68881 tcttatgtta aagaaattat aggaaatgag aatgtaatag actttccatc tgcaatgggt
    68941 tcagaagatt tttcagagat tttactaagg gttccaggag tatttttatg gattggaatg
    69001 ggaagtatta gtcagggata taatttcggt atgcataatc ctaaagcaat ttttaatgaa
    69061 gagggattag tttatggttc agctttattt gctcattgtg cagtaaaatg gttagaaaat
    69121 aattttagta gataataaca taaaatatta ttaaatatca taaaaggtat atcttaaaaa
    69181 gatgcaaaga tatacctttt agaaagtaat atataatttt acttaatatt agatgataaa
    69241 atatttttat gcattttgga ttttaatatt tattttctga tataaataat ttgtataccc
    69301 tttcaggtct accttttgtt gagttttgtt tttcatataa tatagtagcg tttccagact
    69361 ttaagagact acttagaaat ctattagcag ttctaactgt tacatttaaa catgaagata
    69421 attccttagg agtaacttca tctctttgta gaatttcagt aacagatata atcttttgaa
    69481 tagtaagagt agacaattta gaacttttgg caattgtatt tatatgtgga gttactttat
    69541 ttgaaacagt aagtaactta tcacacagta aaggtcctat tgtctcataa ttttcgttga
    69601 ctaagaaact gtagtttaaa tgatttattt tagattcctt attagcactt atggcactag
    69661 acatagcttg ctttatatca ttaccaattc catatccaac acatacttta atatttgtac
    69721 tattttcaat agattctttt atgtaacatg cagtaaaatt tttagttaat gatttaatcg
    69781 tttcacattt agtgaaaatt ttaaaagaat tactattttt ttcaattata aaatcggtta
    69841 acttatcttt tttaatacta tttaatattt tataaacttg gtctagagta gagtcatcat
    69901 aatttgtatc tttaactgtt atatatatta cacttggttg atttcccttc attctatgta
    69961 aatgaatatc ttttattaag ttattaaaag tattttttaa taaatctata tcagggtata
    70021 tgaaatgaaa gtttactcct gcattttgta acataggaac aatactacta aaacgagtag
    70081 tagaaaaatc gattttccct tcattccata gattaatatg tttttttgca atcttttttt
    70141 caagttttgc tatgtcagat aaactcattt tagatgcatt ttcatcaata ctatccatta
    70201 agtctccaaa tgtgccattt gataaataat atgatatatc ttttggatta tctgcccagt
    70261 ctgttaagtc aaagtatgct ctagaaaaat ctaatgtatt atatttaaag ataagcttta
    70321 gaaacatatc atagtaactt tgtaagtcag taccaaactg aacctcccat gactaaagtc
    70381 acagggttcc tgcttcatag aattttgcat actaaaatat gtcttactaa ttctccacag
    70441 gcca
//
LOCUS       DACTZW010000009        69039 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.009, whole genome shotgun sequence.
ACCESSION   DACTZW010000009 DACTZW010000000
VERSION     DACTZW010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 69039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69039
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.009"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            27..302
                     /locus_tag="JAM15_03185"
     CDS             27..302
                     /locus_tag="JAM15_03185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAT6797275.1"
                     /translation="MKKILVACGAGIATSTIVCDRVERLVKENNIHAEVEQCKIAECS
                     TKQEGADLIVSTTILPTTYDIPTIKATGYITGINTTALDKKILNALK"
     gene            558..2258
                     /locus_tag="JAM15_03190"
     CDS             558..2258
                     /locus_tag="JAM15_03190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6797276.1"
                     /translation="MIKQFVKYYKPYKKIFTLDLIAAFLFSLCDLVYPMITRNIMDDV
                     VPNKNLRMLVVFAVALILIFIAKAGLNYFMQYWGHVIGVDMQADMRNEVFTHLQRLPN
                     TYFDNNKSGVTMSRIVNDLMDITELAHHGPEDLFISIVMLVGSFFILIDINIPLTLII
                     FAILPFIIWFAIAKKDKMNIAFMKSRVTIGDVNATLENSIAGMKVTKSFCTEKEELNK
                     FVRSNKLFRRARQDSYKVMAEYYSGMNLYMDILEWVAVIAGGYFTYIGKITLGDFAAY
                     ILYVKMFIQPMKKLINFTEQYQNGMTGFKRFIEIMEQDHQKEAKNPIELENVKGDIEI
                     ENISFTYEDKTQVLDNLSLSIKAGKTIALVGPSGGGKTTLCNLLPRFYEFDKGDIKID
                     GKSIKDVSLKSLRKNIGIVQQDVFLFTGTIRDNILCGNPNATDEEMIAAAKKARIHDF
                     VETLPDGYDTYIGERGVKLSGGQKQRISISRIFLKNPPIIILDEATSALDNVTEREIQ
                     ESLEELSKDRTNLVVAHRLTTIKNADEIIVLTDKGIEERGTHEELVNKNGVYSRLHNN
                     "
     gene            2621..3808
                     /locus_tag="JAM15_03195"
     CDS             2621..3808
                     /locus_tag="JAM15_03195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797277.1"
                     /translation="MEAITAFCLVLISLTIGDIVSAKTKAFVPSVFVSAIIFIVGFWT
                     FFPENIVDLAALGTPLAQLGMLLLITHMGTMMSIKELAGQWKTIVIALAGIVGICVGA
                     LALGTIVFGWDTAVIATPPLTGGLVASIMMADAATAKGLASLSVLAILMYVAQGFAGY
                     PITALMLKKEGKRLLSDFRSGKVTVNTDEEKVKDLPEQKSRFKIIPDLPEKYDTTYMI
                     ILRLGFVAWLAVQFTNLTNEVVSRYVICLIFGVIASELGIVDRKPLNKSGSFGWLMTS
                     LMAFIFAGLAKATPAMLVEMAVPLVGIIIFGVIGMGIFSIIVGKLLGESKEMAFSVSL
                     TSLYGFPPNYILTEEAVKALAETPEEKEFLMDKMLPKMLVGGFTTVTIASVVIAGIFV
                     NLI"
     gene            3868..5031
                     /locus_tag="JAM15_03200"
     CDS             3868..5031
                     /locus_tag="JAM15_03200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HAT6797278.1"
                     /translation="MDIKEITKSYKDYVIKLRREFHENPEKSMEEVRTSKRVKEELDK
                     IEIPYVSAGGTGVIATIKGANPGKTVALRGDMDALQVVECTDVEYKSKNEGLMHACGH
                     DGHTSMLLGAAKVLNDIKDSINGTVKLFFQPGEEVGKGARAMIQDGAMEGVDSVFGIH
                     LWTDVESGIISVEEGPRMASADFFKITVKGRGGHGSLPHQGVDAVLASSAIVMNLQSM
                     VSREVSPLEPLVVSVGVLNSGTRFNVIASEAVLEGTIRLFNPELRKQIPGILERIAKS
                     TAEAYRADAELEYGYLTPAVINDKECSKIATDAAIKLFGEDCITLFEKVTGAEDLAEF
                     MNIAPGALAFVGARNESKGACYPHHHGCFNIDEDALEIGTALYVQYAVDFLNK"
     gene            5182..5985
                     /gene="zupT"
                     /locus_tag="JAM15_03205"
     CDS             5182..5985
                     /gene="zupT"
                     /locus_tag="JAM15_03205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZupT"
                     /protein_id="HAT6797279.1"
                     /translation="MNNVIFAFLITLLAGLSTGIGSCIAFFAKKTNTKFLSISLGFSA
                     GVMIYVSMIEIFPKAQDALTKSMGEKLGSWSTVIAFFIGMAIIAVIDKLIPQEENPHE
                     IKKMENIEEKNIKKNKSLLRTGIFTAMAIAIHNFPEGLATFISALDDVTIAIPIAIAI
                     AIHNIPEGISVSVPVYYATGDKKKAFYYSFLSGMSEPLGAIIGYVLLRNFLNDITLGI
                     VFAIVGGIMVFISLDELLPSAREYGEHHLSIYGLIAGMGVMAISLLLFK"
     gene            6090..6641
                     /locus_tag="JAM15_03210"
     CDS             6090..6641
                     /locus_tag="JAM15_03210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HAT6797280.1"
                     /translation="MEKKIKFKFDWYSSPDKIEKWLEDIEAKGYNLYKINKFGGIFYF
                     HKGSPRKIKYTVDYYYDVENNYFDEHKSNGWNLVFRSIGSFMGTSAWYIWSKEYKDIP
                     PKLYSDSDKKNKVKSILFMNMFIFFMLVVIFIYLLNIEIRNLYSGYGASVTAIVLQII
                     LLILYAVQLYRRLMYYLRLKKFK"
     gene            6892..7605
                     /gene="rgbR"
                     /locus_tag="JAM15_03215"
     CDS             6892..7605
                     /gene="rgbR"
                     /locus_tag="JAM15_03215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgbR"
                     /protein_id="HAT6797281.1"
                     /translation="MIKIAVCEDEKETQLLIEDYLENILKDISIEYEIQKYISGEELL
                     ESNLKDIDILLLDIKMEKLNGMDTARKIREVDNEMEIIFVTSLIDYVQEGYEVRAYRY
                     LLKPIELEELKKHVLTCIKDIEINKESHITIKNKSNTYKIYLNEIKYIEVQKKDMLIH
                     TINKNFDIKYSLGKIEKELNPYKFIRCHKSFIVNLRYVENIKPNAAILESGEEVPISR
                     YRYKEVKEKFLKFLGDTIC"
     gene            7599..8977
                     /locus_tag="JAM15_03220"
                     /pseudo
     CDS             7599..8977
                     /locus_tag="JAM15_03220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428529.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
     gene            9218..9907
                     /locus_tag="JAM15_03225"
     CDS             9218..9907
                     /locus_tag="JAM15_03225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797282.1"
                     /translation="MKVKRNINRVAIIVALNLSLALMAGCMSPVSDKNLSSSEQISKD
                     SLKEQVEDKKDESIELFNNYSQKINDAKGREEVKKDLSQRFSKAIIDSGYSIIDSKSD
                     GSFVVSINGAEKPPEKNIRSLFYSMSEDDKEGKVTIDILCAKEYPEDDKLSESDKYIK
                     FIYNLFKSLTNTNLTEKEIFSMVEEEFNKGVGVVELPYMKDIHVEVNKVKQSTKVLKL
                     SLVYKFDISNH"
     gene            10128..12500
                     /locus_tag="JAM15_03230"
     CDS             10128..12500
                     /locus_tag="JAM15_03230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase/glycerol dehydratase
                     family glycyl radical enzyme"
                     /protein_id="HAT6797283.1"
                     /translation="MSQTNRIEAFRQEYINSKPMICCERARIFTESHKKTEGEAICIR
                     RAKAFLETCKELPIKIFENELIVGTAGKFRRTGILTPEFSWQWVDKEMDTFDKRTQDP
                     YIISKEQIEFIRKEIFPYWKGKSLEEVFLARIPEDTAKILVDTGIIDNDSKWRQAVGE
                     VTPDYQDILFVKGYKGIKEDADKKIKELDISVSENIEKIDFYKSVSIVAEGIMTLAQR
                     YSNLAKEMSKQETDEKRKLELIKISEICMNVPANPPTNFYEAIQFVWFVQLGGILSEN
                     PLALNLGRFDQYMYPYYENDAREGKITESEAQELIEALWIKLSEWVWTISANTANYFA
                     GYNQFQNLTVGGKKRNGTDGTNDISYMCLKATESVKTHQPGLSVRVSQGAPDNFVMAV
                     AKLVKQGTGFPAIHSDSAGAQMLLQDGYDAEDARDWSNCGCVVPHFRKTGQWTSAVNI
                     NFAAALEYAMNEGKSRLTGEKMGLDTKNITEFTSFEELKDEFLKQLAYLVKSSVIGTT
                     VAQQIHKEMVPRPFLSTCVDGCLDKGVDLSKGGAKYNIGPVLTGIGLGVVSNSLAAIK
                     KLVFEDKVTTLEELTKALNNDWEGYEELRKLALDVPKYGNDNDYVDSLAIEVSDFYYT
                     ETRKYKDIFGSKFNSAFMGISNYVPTGKIVGATPCGRKATKPLTEGVSPFVGTDTTSP
                     LAAMKSASKINHDVHTGGTLLNLRLNQDLVETERGLRNLTSMIKSYFALGGFHVQFNT
                     ISNDTLLKAQENPEEYKDLLVRVAGYSTQFVNLSREMQDAIIARNSHSNF"
     gene            12515..13417
                     /locus_tag="JAM15_03235"
     CDS             12515..13417
                     /locus_tag="JAM15_03235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HAT6797284.1"
                     /translation="MSKKGRVVKVQHFSVNDGDGIRTTIFLEGCKLKCKWCSNPDSWS
                     NIVKLGVMKDKCVSCNRCIDVCPQNISSLFDRTQINNKCDLCGECIKVCLKDAICIMT
                     KEMSVEEIVEEVEKDFIFFFESNGGITFSGGEPTLQIDFLRELVDIFYDKGINIAIET
                     CGYFDWNKVNDVFEKIDHIFVDIKSMDDNIHKEYTGVSNKIILDNICRLSKLNKSMVI
                     RVPIIYGVNDSEENIRNTALFVKQNVPGGKMELLPYHKFGIDKYKALGLEDYIYEFDE
                     ICNNHMLKLKEIVELTGVKIIEYK"
     gene            13437..13988
                     /locus_tag="JAM15_03240"
     CDS             13437..13988
                     /locus_tag="JAM15_03240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAT6797285.1"
                     /translation="MDNKFPNVGENLRLLRQEMGISLDKASKMTGVSKAMLGQIERGE
                     SSPTVSTLWKISSGFKINFTTLLNENTNTYEVIKKEEVEPIVEQKGNMKLYPIYPFSP
                     QRRFELFIIELEENCTHVSSTHSHVLEEYVLVIEGKLDLNVDGKTYILESGHSIRFDG
                     TLEHIYKNLNKGKTIFHNIEVYR"
     gene            14152..15024
                     /locus_tag="JAM15_03245"
     CDS             14152..15024
                     /locus_tag="JAM15_03245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HAT6797286.1"
                     /translation="MIIKVSMTVLVLILLYILYKYETQHIETTEYNIFNKKIPKEFDN
                     FKIVQVSDLHNKVFDKNNKVLIDKIESLNPDVIFITGDLVDGENKNFQVALDLIDNLV
                     EKYEVYHIIGNHEQKSLIKKYKHLYKDYFKELYSKKIINMENESVRIYRGNSHLNLYG
                     LIIPLECYPYLFANNKKLELSDNFVEDNLGKVNENEYNILLAHTPFFFEKYAKWGADL
                     VLAGHVHGGIIRIPFVGGVLSPNREFFPKYDWGKYEKDNSTMILNKGLGGSKVLIRLN
                     CKPEIVKITLKYEK"
     gene            15188..16168
                     /locus_tag="JAM15_03250"
     CDS             15188..16168
                     /locus_tag="JAM15_03250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797287.1"
                     /translation="MGDTSRFYESVKNKYPKLKDGTRVHLWPKENIIIGPIYDEEDGY
                     KKSIGNVDSLSWKQIVILAECDGKNTTDDIINILSNRYRNIHNMKEKVMEFFMFYENV
                     YLTFEDDIQTLSSVFEITGNKSYITPLYFTIEIDGDNNTNDYFSEITSLLNCMYEKGC
                     RFIEVIGEDILKNKSMREIFQYMLDHFDLIVVTKDSFTIDRSLIKELDNYRHKVIWKV
                     YSKNDDTRIKLKEDIKITSLIKRGHTVVRGDREKAIKIEDMRFKDTKERFSKYGAEWS
                     HLYISSDGSVKSYSFQKDKRVYLGNIFNNSVEEIFLEMQNKIDKLEIVYQ"
     gene            16669..16890
                     /locus_tag="JAM15_03255"
     CDS             16669..16890
                     /locus_tag="JAM15_03255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797288.1"
                     /translation="MNVNNHKCPECGEHSKKFEIVEENEDCVIFECYTCGTISILKYC
                     ENCKEFVFVNIPNNVETYEYCCGKCNNKI"
     gene            17396..18265
                     /locus_tag="JAM15_03260"
     CDS             17396..18265
                     /locus_tag="JAM15_03260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="HAT6797289.1"
                     /translation="MDYKTIILNRKSVREYKNIDIKEEYLSEIKKYSESCKKLVPEID
                     VDVRIMNKSEVFNNLDKVAGYKGNMIDSPSYIIILSDIKDNYIENSGYIGESIIFKVT
                     ELGIGSCWVTFEDGKKVKEKLGINSDKEVTGIIAIGYGENVSNAKVLNATKTGQNYSK
                     SDMQVVTDKGSTRLGVEDVVYMNEWGNVASIEILEERALLDAFHYARLAPSTLNRQPW
                     RFIVDGGTVVLAVRKDGHTNLYEEKIDIGIVMLYFATIISATMFDLKWNLGTPDKDYK
                     VPEDYKIVGYCNI"
     gene            18491..19357
                     /locus_tag="JAM15_03265"
     CDS             18491..19357
                     /locus_tag="JAM15_03265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAT6797290.1"
                     /translation="MEWINKLNQAITYIEENLESGVDYAEAAKIACCSTFHFQRMFSY
                     IAEVPLSEYIRRRRMTKAAFELQNSNIKILELSEKYGYDSPTSFNRAFQNIHNISPSA
                     ARAKGVVLKAYPKMTLSIYVKGNVEMQYRIVEKKGFRIVGIKESMNMIVEECFEKVPK
                     LWAKCIKNGTIDKLSELINNEPCGLLGVSVCTNSKGLDYYIAAPTDKPVLEDTREYLI
                     PSGTWAVFECVSPMPNALAIQELQKRIITEWLPSSGYVYANLPDIELYPNGDINAPDY
                     TTEVWIPIQKPS"
     gene            19531..19728
                     /locus_tag="JAM15_03270"
     CDS             19531..19728
                     /locus_tag="JAM15_03270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004631111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6797291.1"
                     /translation="MKNRLEEIRKERGIKQEELASILQVSRQTIGSLENGRYNPSIIL
                     AFKIARYFDMNIEEIFIYEEE"
     gene            19731..20174
                     /locus_tag="JAM15_03275"
     CDS             19731..20174
                     /locus_tag="JAM15_03275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797292.1"
                     /translation="MKKNMLYVGIIYFICGILLVLLATFTEFSFEAFIWGLSGAALGP
                     GVCMILQYMYWSKPERAVDYEEKIKNQRIEMNDERRIMLRDKAGRITNQIMSYVLVIL
                     IFIVSILSVFSVMVISKWVLVVLGLLILFQFICGVVVYNKLDKKL"
     gene            complement(20361..20448)
                     /locus_tag="JAM15_03280"
     tRNA            complement(20361..20448)
                     /locus_tag="JAM15_03280"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20412..20414),aa:Leu,seq:caa)
     gene            20600..23248
                     /gene="polA"
                     /locus_tag="JAM15_03285"
     CDS             20600..23248
                     /gene="polA"
                     /locus_tag="JAM15_03285"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HAT6797293.1"
                     /translation="MEKKLIIIDGNSIINRAFYALPEMNNKEGLKTNAIYGFTTMLFK
                     MIDIYKPTHISVAFDRKAPTFRHLEYKEYKAGRKGMPDELAEQLQPLKDLLDKFKINR
                     LEIDGYEADDIIGTVSKKAENNGYKVYIVTGDKDAIQLASDNTTTLITKKGVGEVEEY
                     NFNSVIEKYEMTPAQFIDLKGLMGDKSDNIPGVPGIGEKTGIKLIKEFSSIENLIENT
                     DKLKGSVKKKIEENKEIAIQSKRLATIIRDVPIEVDLDSMVFGDYDKDELLDKFRYFG
                     FTSLLSRLVDLVDSDDTEHVEEKIEILKLKDTEKFIDEVNKKGQVILKTVRGQGNILE
                     KNIIYIFISVDGEKIYYVDSNEVSKLDSIFSNNEIKKYGYNLKDDYISLKPYNINLEN
                     MYFDITIAEYLIDSTSSTSYDCSAIAMKYLSKKVKSKEELLGKGVKSKNYEDLEFEDL
                     AEYMGQIICTVKETIPMMERSLMDMSMDGLFYHVEMPLVEVLGHMEYEGIKVDKSILD
                     ELSVEFKEIIATLEKEIYELSGEPFNINSPKQLGVILFEKLELPIIKKTKTGYSTNAD
                     VLEKLRDKHPIIDKITEYRQIVKLNSTYVEGLLNIINPESNRIHSSFNQTITTTGRIS
                     STEPNLQNIPIKMEMGRKIRKVFIADDNCKLVDADYSQVELRVLAHMSQDENMIEAFK
                     HHEDIHTKTASQVFNVPMEDVTSELRGAAKAVNFGIIYGKSDFGLADDLNIPVPKAKE
                     YIESYFAKYHKIKEFMDTTVEKASEDGYAVTILNRRRYIPEIKSSNFMERNRGKRFAM
                     NAPIQGSAADIIKIAMINVHKKLEENNLKSKLILQVHDELIVEAIDDEIDIVKKIVKE
                     EMENAVNMDVHLDVDLNVGSSWYETK"
     gene            23257..23859
                     /locus_tag="JAM15_03290"
     CDS             23257..23859
                     /locus_tag="JAM15_03290"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HAT6797294.1"
                     /translation="MLILGLTGGIGCGKSSLSNIFRNLNISILDADIISRKIFEDKLL
                     LEKVFVHFGQSIKNDDGTLNRKALGKIVFSDEEKLKELNSLTHPRIREKIISEIEELR
                     KKGENIVVLDAAILVESGFLDMVDKLLVVTCKQEVQISRIQKRDNCSKQEALSRINSQ
                     MSQEEKSKYGDYIIDNSGTITELESKAHKFIEYMKENWRE"
     gene            23852..24406
                     /locus_tag="JAM15_03295"
     CDS             23852..24406
                     /locus_tag="JAM15_03295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HAT6797295.1"
                     /translation="MNSKKVLILSIFIILFGALLMESKVIHKFLYPKKYSEYVEKYSK
                     EFNLDENIVYSVIKAESKFNSSAVSKKEAKGLMQILDITRDWGAEELNLKNVDIFDPE
                     TNIRLGCWYLSKLYKEFGKLDLVIAAYNGGSGNVKKWLENNEYSKDGENLHDIPFKQT
                     SKYVEKVKNNYEHYNKIYGKKGKN"
     gene            24406..26121
                     /locus_tag="JAM15_03300"
     CDS             24406..26121
                     /locus_tag="JAM15_03300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAT6797296.1"
                     /translation="MKRIKVLTVVLAITLMVAGCSNTKTKQSSSDSSLQSQSSIDAKY
                     INLTMVTPKTINPITNTDKSVGYIMNLVYDSLFTIDENYNVIPQLVKEYNIAQDGMSI
                     DIKLKDAKWHDGKNVTSNDVNYTIGLIQKSADSPYNEFTKNIASVNIKSDKDFTIKFK
                     ARYAFSIDSLIFPIVSQNHLDSKDVNDKNNNMIGNGKYKIESYTEREGMVLSVNKDYY
                     EEVPKTMKNIKVGMVPNEEARTSMVMALDSDITNVTLNDLSKFQEKEFNITKYQGRDY
                     ECVLFNYNNPFFKDVNFRKAIAHSIDKDRIISEGYMDDATPVNFPLNSKSKYYNSEMK
                     DLEFNKDKAIECLAKVEYANINSVNQNDNKVKNQKKSAKKNSKKLTPEEEAKAKKAEE
                     DRIKKEAEEKKNREKEEVKKSLSEMNLKIIVNRDNSERIKTANIINENLKAIGINSTV
                     NQLSDKDMENALNSKNYDLALVGWKLSIIPDASSIIASSGYTDDKLNGYMSALTSSTS
                     EIETKKAYKDVQTYIKDNATFISLAVRNNYIVSNSRLKGKITPNDFDVYEGISNLDIK
                     SNESN"
     gene            26194..26406
                     /locus_tag="JAM15_03305"
     CDS             26194..26406
                     /locus_tag="JAM15_03305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HAT6797297.1"
                     /translation="MKKKLLVEGMSCGHCVNHLKTALTEDIDGIEVLDVDLENKCASV
                     DMKDDVSIEKLKEVIAELGFELKGIE"
     gene            26607..27206
                     /locus_tag="JAM15_03310"
     CDS             26607..27206
                     /locus_tag="JAM15_03310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797298.1"
                     /translation="MESRGYKEDLKKMILDMAHKELESYVSQKGAKKYFEGNLDKIIN
                     NNIKKFNQSIGLNRVYLKMLKKCAYQESVTSISRTIKKEALFKSKKELFAFSEYLKLD
                     INKRLSYNQILRKISRYIYYNRSSYAQKYVVFKRGDEEYLLEPEKIKDELISSYRSKT
                     REDMRSIAKLLDIEVEDDYNAEDIRKKVINYIIKEKLKS"
     gene            27434..27805
                     /locus_tag="JAM15_03315"
     CDS             27434..27805
                     /locus_tag="JAM15_03315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAT6797299.1"
                     /translation="MKFNFCHNNFNVTNLEKSLDFYKKALGLKEVKRKEAEDGSFILV
                     YLGDGITSHTLELTWLRDWDRPYNLGDNEFHLALEVEEFDEAKKLHKDLDCICFENES
                     MGIYFIADPDNYWIEILPKNH"
     gene            27937..29211
                     /locus_tag="JAM15_03320"
     CDS             27937..29211
                     /locus_tag="JAM15_03320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HAT6797300.1"
                     /translation="MKKAIAALGIGAVAVSVSSINASALEKGTVTASALNIRSGPSSD
                     CDKVAKLYKGKTVEILEKSNGWYKVRVSSSVVGWGSAKYISTSGSSEGTSNQNNPTSS
                     GTTISGNGKVNVSSRLNVRSGAGTNYSLVGKANNGDVVKLLEQSNGWYKIKLSNGVTG
                     WASSQYISKTSEDVGTNNSSNSNSTNNSDKKPSSEESIEGKNGKVTSAVSLNVRSGPG
                     TSYSIIGKLNGGDVVELKAKSNGWYKVKLSSGTIGWVSASYISETNEDTKEKPNSSSN
                     QNSQSNSNSKPSFTGNSDKSTAKGSTIVDFAYTLIGIPYQWGASGPDKFDCSGFTQYV
                     FKHSVGVSIPRVSREQANFGSAISMGNYAPGDLVYFDTDGDGTTNHVGIYVGNSKFIH
                     CSGTQTNPNKVKVDNLTSSYWSKVLLGARRFV"
     gene            29322..30266
                     /locus_tag="JAM15_03325"
     CDS             29322..30266
                     /locus_tag="JAM15_03325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797301.1"
                     /translation="MNRRKTIYRGFNNNRHKIDLRKYVITIACLCLIGYYSYTKIKDS
                     KILEYVSAKIPFLNNSSDITYKDISDELNSIKKGKKSKSQTNSDDKQENNPEKAVNNT
                     KEPEEVKLATIEGWDMYTIQVAAIDNNDDLKKIQTSLVNNDIPFSVMEKDGVKKIQTY
                     SSFDENDVRKQISSVRKVFPDAFLSHLDAPMLSLEYTSNYAYIESISKELNKLITNFK
                     EESSFWSNAENNVDMEKYNTILTNRKAISQNISKEAEKIDYSEMRLFKDNLIEYVKNV
                     NEKIDTASKAANEEKYSVSKSLLLSSMQEYSMFINSIK"
     gene            30482..31819
                     /gene="rsxC"
                     /locus_tag="JAM15_03330"
     CDS             30482..31819
                     /gene="rsxC"
                     /locus_tag="JAM15_03330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002844616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxC"
                     /protein_id="HAT6797302.1"
                     /translation="MKLLTFKGGIHPPYRKEYSNTKALEKAQAPKIVYIPLQQHIGAP
                     AKPIVEVGDEVKFGQKIGEQQGFVSCNVHSSVSGKVIAIEQHEVPGGSAQCVVIENDF
                     KEELHESVQPKGQLEDLSKEDIVGIIKEAGIVGMGGATFPNHVKVSPPPDSKAEVVIL
                     NGAECEPYLTADHRLMVENPEDVVFGLRALMKVLDVKKGFIGIETNKPDAIEAIQNVA
                     KDYSEIEVVGLQVKYPQGAEKQLIYACTGKEVPSGGLPIAAGAVVDNVATAAQIAKSI
                     KTGMPLVERITTITGSCIKEPKNLITKVGTLVSEIIEQCGGFKEDKKIGKVIMGGPMM
                     GIAQYTTEIATNKGSSGILCLDEEESRTPDIQNCLRCGRCTDVCPSFLQPLFISAYSL
                     KDDYDTAEYHRAMDCIECGSCSFICPARRPLLQSIRSAKREIGAKRRKQAAQK"
     gene            31842..32819
                     /locus_tag="JAM15_03335"
     CDS             31842..32819
                     /locus_tag="JAM15_03335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit D"
                     /protein_id="HAT6797303.1"
                     /translation="MENKLIVSSSPHVRSNEDTSYIMKQVIIALLPAAVAGVYFFRLN
                     ALSAMFFCILGTVGTEFLYQKFTKQKSTIGDFSAVVTGLLLAFNVPASLPWWMCLVGG
                     IFAILVVKMVFGGIGCNFVNPALAARAFLLASFPVAMTAWTQPGVNWIGKNLDAVTTA
                     TPLSFLKNGAAGLADLSSNGISLADMMIGNIGGCIGETSAILLLLGGVYLMYKGIINY
                     VIPVFYIATVFILTFLLGGFNITFAIYQLFAGGLMLGGFFMLTDYTTSPMTKKGQIIY
                     AVLAGLITTVIRMYGGYPEGVSYSILLVNCLAPLIDKFVRNRVFGEVAK"
     gene            32819..33388
                     /locus_tag="JAM15_03340"
     CDS             32819..33388
                     /locus_tag="JAM15_03340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit G"
                     /protein_id="HAT6797304.1"
                     /translation="MNSMVRLGGTLLAISAIAALALGATNQVTAPVIEQRNIQANNEL
                     RKAVLPEAKEFKEMDKSTYKDLGDGLIAEVYEGLDGSEVVGYTLKAKPSGYGGEIEVM
                     VGISSEGQVTGVDIGNMSETAGLGAKAKDDAFKGQYKGKTAEPLEVAKGSTTADNQIL
                     AISGATITSTAVTTGVNAAIDVFNSALNK"
     gene            33398..33994
                     /locus_tag="JAM15_03345"
     CDS             33398..33994
                     /locus_tag="JAM15_03345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002844610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit E"
                     /protein_id="HAT6797305.1"
                     /translation="MMNLAKVFKNGLIDENPTFVQVIGMCPTLAVTTSAINGIGMGLS
                     TAAVLICANLVISLIRKITPDKIRIPIFIVVIATFVTIVGMLLKAYVPALDKALGIYI
                     PLIVVNCLILARAESFAFKTGAMPSIVDGVGQGLGFTVALTIIGAVRELLGNGSLFGM
                     TLFGASFQPVLIFILPPGAFLTLGFLFAGFNKLRSKKA"
     gene            34009..34584
                     /gene="rsxA"
                     /locus_tag="JAM15_03350"
     CDS             34009..34584
                     /gene="rsxA"
                     /locus_tag="JAM15_03350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002844590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxA"
                     /protein_id="HAT6797306.1"
                     /translation="MNLILLFLSIVLVNNVITSQFLGICPFLGVSKKVDTAVGMGVAV
                     TFVLTLASIITYFIQILLVKTGTGFLQTIAFILVIASIVQFVEMVIQKMSPSLYQALG
                     VYLPLITTNCAVLGIALVNVQKSYNLVETIINGFGAGAGFTLAIVIFAGIRERLELAD
                     IPEAFKGFPITLISAGLMSIAFLGFTGLIKL"
     gene            34600..35571
                     /locus_tag="JAM15_03355"
     CDS             34600..35571
                     /locus_tag="JAM15_03355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit B"
                     /protein_id="HAT6797307.1"
                     /translation="MVILTAVLVLGIMGLIFGIVLDFASKKFAVEVDERVEAILGVLP
                     GANCGGCGFPGCGGLANAIVEGNAPVNGCPVGGADVGAKVGEIMGISAEAGEKQVAKV
                     ICKGTCSSAKDKYEYEGISDCRAANVLNSGAKMCKFGCLGLGTCKDACKFDAISIVDG
                     IAVIDEEKCVNCGKCKEVCPKGIIITKPESQEVVVECNSKEFGKAVKEKCTAGCIGCG
                     MCVKACKFDAIIFEDKIAKIDPNKCVGCMQCVAKCPTKVISGDITKKKKVTIDQELCV
                     GCTVCKKQCKFDAIEGELKEKHKVDADKCVGCHLCMEKCPKKAIKIL"
     gene            35791..36375
                     /locus_tag="JAM15_03360"
     CDS             35791..36375
                     /locus_tag="JAM15_03360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HAT6797308.1"
                     /translation="MNIILASASPRRKEILENTNVRFDIIKNEIDEIILEGETPKHLV
                     MRLAFEKSMSVASEHNEDVVIGADTVVVLDNAILGKPKDESCARDMLKRLSGREHQVI
                     TGISLINLCEDKKVIDYVISNVKFKTLSEQDIEDYLKTNESFDKAGAYGIQGYGALLV
                     EEIRGDYFNIVGLPISRLGDLLKKYFSINLFYGV"
     gene            36420..37079
                     /locus_tag="JAM15_03365"
     CDS             36420..37079
                     /locus_tag="JAM15_03365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HAT6797309.1"
                     /translation="MAPEERPREKMLAKGVKSLSNAELLAILLRTGNKNKNAIELANY
                     IINRDIQGIRHLEDMTIEELCNIDGIGLSKSTQIKAALELGSRVASFKPIKYKIRNPW
                     DIQRYYMDSLRYLKKEVFKAVLLNTKNEIISDVDVSIGTLSSSLVHPREVFKEAIRRS
                     ASKIIVMHNHPSGSVEPSREDKNITSRLIKCGEIIGIEIIDHIIIGDGLYFSFKENMI
                     I"
     gene            37149..38210
                     /locus_tag="JAM15_03370"
     CDS             37149..38210
                     /locus_tag="JAM15_03370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HAT6797310.1"
                     /translation="MAKEKKKEKKGFFSFNKMTKDMGIDLGTANTLVYIKGQGIVVRE
                     PSVVAIRDDSKEVLAVGEEAKKMIGRTPGNIVAIRPMKDGVIADFDITQSMISYFIQK
                     AADKKGVVSPRIAICVPFGVTEVEKRAIEEAARQAGAKDAFLIEEPMAAAIGAGLKVE
                     EPEGNMVVDIGGGTSEIAVISLGGIVTAKSIRIGGDEFDESIVAYVKKEYNLMIGERT
                     AENVKINIGSTFKDDEEINMQIRGRDLISGLPKTIEICSTEVREALKEPVSSIVDAIK
                     STLERTPPELASDIMENGIMLTGGGALLRGLDKLITQETGMSVQIAETPLDCVALGTG
                     KSVEDQEIFEKVLMMNTKN"
     gene            38220..39113
                     /gene="mreC"
                     /locus_tag="JAM15_03375"
     CDS             38220..39113
                     /gene="mreC"
                     /locus_tag="JAM15_03375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HAT6797311.1"
                     /translation="MALRFDKNKNEKKKINVKVIATGVVAITLIGIVGISIGKFSSGS
                     PVNLGVASDAITSVGKGINDGFSFIKNGFKDVANFKDNSKKVKKLEEENEKLKKDMIA
                     LNAKLDKTESLEELKKTLNFVQEEYKATSISASVVGKNDGNWYESFVIGAGKNSGVKK
                     ESIVMNGSGLVGIVYEVSNNYSKAISLLDSKASVSFKLAKDANAKGTITQNTTLDNKD
                     SYNSKGYLQGYMFDSSYNVIQGDIITTSGLGFFPDGIPIGEVEKVVDDKDKSLKYVVV
                     KPYVDFKNINDVVVIEPRNIG"
     gene            39128..39616
                     /gene="mreD"
                     /locus_tag="JAM15_03380"
     CDS             39128..39616
                     /gene="mreD"
                     /locus_tag="JAM15_03380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HAT6797312.1"
                     /translation="MKKVLLCLLGIVLMTIENSITNYIDIFGISFNLVLIYVTIISLY
                     LDELEGGIIAAIIGLIKDITVGGIFGVNALILFIIAYAIGYMRDQLYKGSYIITFVLI
                     FIGSLIDSIVNIGTSSIIYQSYNISTLFVKGLLVAPIVNSLIGLVIYRLSKRAVLKLK
                     ED"
     gene            39628..42606
                     /locus_tag="JAM15_03385"
     CDS             39628..42606
                     /locus_tag="JAM15_03385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HAT6797313.1"
                     /translation="MEENKQVDRLKIIKIVMGVIFLAILVKIIYMTTFKYEYYNELAE
                     NKTYKKLAIEAPRGEIKDRYGRLLAGNKNLFTVQVSGNDINKKDANKHSRANEISLKL
                     INLLERNGEEYVDEFPIYVENGKYYYTYDRDIREYKSENGIPNDYNAKESFYYLVDKL
                     ISAGILSQEDKRLDATRLQAKLNENGYYPPILVSKWMFTAERDKRDWLASYKIKETKL
                     SAKEAFEKVRNSDALEIDKSLSDEDARKIMVVRDLIKSKGYSQYNPVTIAKDVGETTI
                     AQIEESAMDLVGVSIAVEPVRYYPNGSLASHMLGYVGKMPSTQIESYLQKGYETGDMV
                     GLAGVEKSNESRLRGTDGYKMVKVDALGRISKEIESKKPKSGDTVYLTLDKDLQEVSD
                     NALKQIIEVASKGGTFKSKFGDKPISAYAGKAQSAALIAIDVKNGEVLASSSYPNYDP
                     NKFAKGISTEDYKALQPKNPNDLLAGSPLLNLVTQGEFQPGSSFKMVTSMAALENGLD
                     PNFTINDPGVIMLGKKSFGDYVWNHGRGNHGMTNLYKAIQESCNIYMATIGTGKTWPD
                     GKSIGIDMNANKILEYAKLFGLDQNTGLQDEVEERAGKVPSTEDKLKSTQALLKSNLE
                     REMANDFVDITREKNPKEYEKRINEIVSWAAEKKTPGRVETMNRLKKMNVKEDRIEEV
                     ADLAVFSYFNFAKWSTADTFNLAIGQGENAYTPAQISRYVAAIANGGNLVELSVVDRA
                     VSSDYSSVKINDQKKVEKIPFKNPDNLKELTKGMKLVARQGTAKSAFADFPIDVAAKT
                     GTAEKSGKIPTDNEYEYLKSHMSSYNVNLNDAIKLADKMKAEKEKELSLAKEKEIKKK
                     LENKDLKDEERKKLEEELEDGVKVRLEDTDKVNSSYLRKAIKELNPKITDDQIDRFKQ
                     DYGSFTWTVAFAPADDPEIAVVCVIPQGDSSVFSLLPTREVIGTYMGLEPTNSKNDNK
                     TNDVNNSSDENINFESQINR"
     gene            42704..43387
                     /locus_tag="JAM15_03390"
     CDS             42704..43387
                     /locus_tag="JAM15_03390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinC"
                     /protein_id="HAT6797314.1"
                     /translation="MSLREICSQELVEFKGNKRGIIVNIKREAPFEEIQEKIINKLEA
                     YVGFFNGAKISKINSDCLTDMEILELKEGITSRFDVEFVEDQKIEENSNFPTKYVNTL
                     RSGENIEFEGDVVILNDMKPGSKVLSKSNTVVMGDINAGAKVVAGGNVFVMGKIEGFV
                     HAGAEGNEFAYVVAGNLNPKILQIADNIAEAPDDEENYESESEISPEIAFVSNGRIVI
                     ESYLSKLDK"
     gene            43411..44208
                     /gene="minD"
                     /locus_tag="JAM15_03395"
     CDS             43411..44208
                     /gene="minD"
                     /locus_tag="JAM15_03395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="HAT6797315.1"
                     /translation="MSEVIVITSGKGGVGKTTTAANLGTALSLENKKTVVVDADIGLR
                     NLDVVMGLENRIVYDIVDVVEGTCRLKQALIKDKRFDNLYLLPAAQTRDKNAVSVEQM
                     IDLCEKLKESFEYIIIDCPAGIEQGFKNAVAGADRAIVVTNPEISAVRDADRIIGLLE
                     ANEIKEIRLVINRIRNDMVKRGDMMDKQDIIEILAIDLLGLVPDDESIIISTNKGEPA
                     ILDSKSLAGQAYKNIAKRILNEEVPLLDLEVEDGFFGRLKKMFSMAK"
     gene            44226..44510
                     /gene="minE"
                     /locus_tag="JAM15_03400"
     CDS             44226..44510
                     /gene="minE"
                     /locus_tag="JAM15_03400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="HAT6797316.1"
                     /translation="MLDLFRVFSNEAKTSKSVAKERLKLVLVHDRVDCSPQLLEMIKT
                     DILKVIANYAEIEDDGLEIKMSKCRGEHDDKPVSALVANIPLKNIKDRCM"
     gene            44595..45725
                     /gene="rodA"
                     /locus_tag="JAM15_03405"
     CDS             44595..45725
                     /gene="rodA"
                     /locus_tag="JAM15_03405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein RodA"
                     /protein_id="HAT6797317.1"
                     /translation="MKKININYKSTIKLIKQLDWKLIVTVLAIFIFGLVILSSATHAN
                     STGSYNQLIKQGLAFVLGIGMIIVILFFDYNLLGRYYKALYIISLILLAIVLLPGIGT
                     VKGGARSWINLGPLDLQTSEIVKLTFVLSYAKILESKKDKLNTLKEVMPVVVYSLPFI
                     GLLIAQPDLGTGIVFCCMIFAMLFTAGLSSKLIKRGIIILLVSMPLMYLMMADHQKVR
                     IEAFLNPEDVTLKGNYQVMQSLIAIGSGGVTGKGLYNGSQNQEDFLPVQDSDFIFAVV
                     GEELGVIGMAVLIILFMIFLLRLLAIARDAKDFYGTLIVVGVMGMFGYQIIQNIGMTV
                     ALIPVTGVTLPFVSYGGSSLLTSLANLGLVLNVCMRRKKINF"
     gene            45766..46179
                     /locus_tag="JAM15_03410"
     CDS             45766..46179
                     /locus_tag="JAM15_03410"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HAT6797318.1"
                     /translation="MNIALVAHDQMKNTMVGFCIGYESILKKYGLYATGTTGKRIMDE
                     TELNINRLASGPLGGDQQIGSLIVTQEIDLVIFLRDPLTSQAHETDIQALIRLCDVYH
                     VPIATNLASAEIFIKALDRGELSWREVRKSKSQRI"
     gene            46663..46992
                     /locus_tag="JAM15_03415"
     CDS             46663..46992
                     /locus_tag="JAM15_03415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAT6797319.1"
                     /translation="MQLNKEVLKGYIDILIVSILEKKDCYGYEIAKQVRERSEFELKE
                     GTMYLALKRMESKNLIKSYYSNEQSSGGRRKYYNLTNEGKDFLEIKKQEWRFIKKVMN
                     QFLGEVD"
     gene            46996..47787
                     /locus_tag="JAM15_03420"
     CDS             46996..47787
                     /locus_tag="JAM15_03420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797320.1"
                     /translation="MKLIDEYLDKLYKKCDNKSTIELKQEMRCHLIESANEFKLEGLD
                     EEEACKKAIERFDDGDEMQYELCNIIKELSLSLDRHKSIVMGFKKVLGYISIIAFLIS
                     GFMWYYNNSLQHNMYNLGKELDGEIKQLTERHDMTKIGEYKLELEKILDKDKYSKVKA
                     LRLYVIDMKDGNTNLSSSGLNSNMVYEREADYNNISNFIQHLGYNGKDFLDKNGNIVN
                     PDIFLEYFFYFESEMLIPVAFAFGLLCIIAYFILRFKISLIKNNN"
     gene            48352..49434
                     /locus_tag="JAM15_03425"
     CDS             48352..49434
                     /locus_tag="JAM15_03425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HAT6797321.1"
                     /translation="MKKIRKLSTKLLIATMVLTSCMNVTVYGMTAKDVTAKTPKSYVA
                     GTNSIYGPKLSQAQLNSVAQATADFMNKKITKNMTTDAKIRVAYNHIKNNTTYVNWNA
                     AEGANTAYTLVTKKGVCSGMCRSLKALCDAMGIECYYVHSTTNDHQWNLIRFEDGRLY
                     HVDIDANKSAGADIIYKSLTHPLPFDKKAYPAVGEVVKTQNPTPTVKKPTPAKPSAPV
                     GPGNHTMIADQEGAILDEVYGNNLRPKIERYEGVQCSLINSSINTIKFTSKNSNLDPS
                     RHTVSVIGFMNTPYGMVALAPDGVPVEYPFEYDKPFSLDFTGKNLSAAELSKKCKENN
                     VIIKVEIGETTSNSGIGLVAYARYMN"
     gene            complement(49638..50831)
                     /locus_tag="JAM15_03430"
     CDS             complement(49638..50831)
                     /locus_tag="JAM15_03430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HAT6797322.1"
                     /translation="MSKVFEVKKDIYFTGVVDEGLKVFDIIMETEFGTTYNSYLIKDE
                     KTVLFDTVKANFKDEFLSNLSEVTDIAKIDYVVIHHTEPDHAGSLKYLLDINPNIEVY
                     CTKAAKLYLDGQINRPFNCHVIKDGEILNIGKRNLRFITAPFLHWVDTMFTYIEEDKT
                     LLTCDAFGCHFASVDAEVVNSEDYLKSAKHYYDCIVKPFAKHVLSAVDKVVGLNIEFD
                     TILTSHGPMLTKDPMAAVKRYVEWSTEAVNTTNQNQVSIFYLSAYSNTLEMAKKIKEG
                     LDKEGAKAELYDLEDMTLTEMHDTLVVSKVILLGSPTINKTMVKPMWDLFSVIDPMAN
                     QGKIAGVFGSFGWSGEGITMAETLLKSMSFKMPVESLKKKFFPSEETLKECMAFGAEF
                     AKLVK"
     gene            51150..52994
                     /locus_tag="JAM15_03435"
     CDS             51150..52994
                     /locus_tag="JAM15_03435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03960 family B12-binding radical SAM
                     protein"
                     /protein_id="HAT6797323.1"
                     /translation="MNKVDLKKILKKVEKPARYLGNEINSIHKDTSNSELIRYAHCFP
                     DLYEVGMSHLGSHILYDVINKDEDVFCERVYSPAVDMENIMREKSIPLFALESREPIT
                     NFDFVTFTLQYELSYTNILNILDLANIPILKEERTLEDPFIMVGGPCAYNSEPLADFV
                     DVVILGEGEEVNLEVVNEYKEWKKNKTTREDFLYKISSIEGVYIPSFYDVKYNEDGTV
                     QSVTPNREGITKNPTKRIIKDVETVDYPEKLIVPYIDTVHDRIVLELFRGCTRGCRFC
                     QAGMIYRPIREKSVKRLKEILDKLVKNTGYDEISLSSLSTSDYSKLSELTDYLVDEYA
                     SNNIGISLPSLRLDNFSMEIADKIQQVRKSGLTFAPEAGTQRLRDVINKGVTEEDLEN
                     ATERAFEMGWNSVKLYFMIGLPTETYEDLDGIAKLAYKVIDIYRKVNGGKLKRSFSVT
                     VSTSTFVPKPFTPFQWHGQDTTEEVINKQRHLVNKLRNNNIKYNYHDSKTSLMEAVVA
                     RGDRRIGKVIYDAFRLGAKFDGWAEHFNLDIWKEAMEKNNLSIDFYAHRNRNYEEVFP
                     WDHIDVGISKKFLIREDENAKKEKITSDCRHNCNGCGINIHDIGRGLC"
     gene            52996..53697
                     /locus_tag="JAM15_03440"
     CDS             52996..53697
                     /locus_tag="JAM15_03440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2344 domain-containing protein"
                     /protein_id="HAT6797324.1"
                     /translation="MSKIIRVKFKKEGDMIYISHLDLQRLLQRAFRRAEINLSHSQGF
                     NPHPKMSYGNALALGTESQGEYVDIEIEEDDLSVEEFLNKVSIQLPDGIDFIKAKEID
                     RQTPSLSSVIDYGEYLFNIDLKRPMTKEFVKRKVIDFMNNKEIIITKKNKKGKMVEVD
                     IRPMIRTFDVLNLEDEHITLTATIATGSKTNLNTNILIPKILEMFELDIDPLDVDILR
                     RDLYVLEDGELVTPM"
     gene            53715..55136
                     /locus_tag="JAM15_03445"
     CDS             53715..55136
                     /locus_tag="JAM15_03445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rne/Rng family ribonuclease"
                     /protein_id="HAT6797325.1"
                     /translation="MKKIVIESLIGSQKTAVLEDERLTELFVEDNLNKKTVSNIYRGI
                     VKKVIPGIEACFVDIGFKKLAYLQLKKGSTIKSGQDILVQINKEEIGTKGAKLNTEIS
                     ISGRYIVYIPSNDRTTISNKITDEKERFRLKKITKAVNKENLGLIIRTEAQGCTHDEI
                     KKDIEELKLKYENILKEYKLGIGPKLLYKSLDFATKYVKDNVNDDIESIITNSYDKYS
                     ELKSILRGIDKTYVDKLCLEENRDVFDLYRIESKIEKLLNKKVWLKSGGYLIIEKTEA
                     LTVIDVNTGKFIGTGKLDETVYKTNLEAAKEIVRQLRIRDIAGIIIIDFIDMHKKKHQ
                     KEILHILEEEFNKDKRKAEVLGMTKLGLVEVARRREKESIDKYYLMSCPCCDGEQTIK
                     SVHYILDSIEKEIMRISEHTVYKNIMVEFNDFIFEQIKEYYMDIIDKIGEKYNIKISL
                     NANSTLKHNKTNVIFDKIVDNKM"
     gene            55237..55548
                     /gene="rplU"
                     /locus_tag="JAM15_03450"
     CDS             55237..55548
                     /gene="rplU"
                     /locus_tag="JAM15_03450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HAT6797326.1"
                     /translation="MYAIVKTGGKQYKVSEGDVLFVEKLEANAGDVVTLNEVLACSKD
                     GELKLGSPVVEGASVQAKVVEQGKAKKVIVFKYKAKKDYRRKQGHRQSYTKIVVEKIN
                     A"
     gene            55563..55880
                     /locus_tag="JAM15_03455"
     CDS             55563..55880
                     /locus_tag="JAM15_03455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HAT6797327.1"
                     /translation="MIKVKYYYNDDFLLQGFCLKGHADFAEIGYDIVCAAVTSNAIAV
                     INSLDKLQKIEFEKVVGEEGHIECIVKDTHVKDAQLLLNHFQLAVEEIKREYPKNIKI
                     LKK"
     gene            55894..56184
                     /gene="rpmA"
                     /locus_tag="JAM15_03460"
     CDS             55894..56184
                     /gene="rpmA"
                     /locus_tag="JAM15_03460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HAT6797328.1"
                     /translation="MLNMNLQLLASKKGVGSSKNGRDSISKRLGVKRFDGQLVTAGSI
                     IVRQRGTKIHPGTNVGKGSDDTLFALVDGTVKFERKDKKRKKVSIYPVAIAE"
     gene            56295..57572
                     /gene="obgE"
                     /locus_tag="JAM15_03465"
     CDS             56295..57572
                     /gene="obgE"
                     /locus_tag="JAM15_03465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HAT6797329.1"
                     /translation="MFIDKARIFVKAGNGGNGSVAFRREKYVPAGGPDGGDGGRGASI
                     IFEVDLGLRTLMDFKYQKKYQAQNGGDGSKGKRAGKNGENLVLKVPAGTVIRDEATGL
                     VLADLKKEGDTAIVAKGGIGGKGNQHFANAVRQAPAFAKSGTDGEERWITLELKMIAD
                     VGLLGFPNVGKSTFLSVVTKAKPKIANYHFTTLTPNLGVVQTKFGDSFVLADIPGIIE
                     GASEGIGLGHEFLRHVERTKVLIHIVDISGLEGRDPIEDFDKINDELKLYNEKLSKRP
                     QVVVANKFDILEDESKFEKFKSELEGRGYTVFKMSAATRQGIDEVIAYVSKMLKEVED
                     VELVSEEEMYRPELDIGTEEELSIDIEDGVYVVTGKALRRIMYSVNFDDMESLQYFQK
                     AMESQGVFDRLREMGIEDGDVVKIYELEFEFYN"
     gene            57624..57992
                     /locus_tag="JAM15_03470"
     CDS             57624..57992
                     /locus_tag="JAM15_03470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbY family RNA-binding protein"
                     /protein_id="HAT6797330.1"
                     /translation="MLKGKQRAYLRSLANTLKPTTQIGKEGVTESFLEQLDGMLRTRE
                     LVKVTILENAGLDTKETANAVCEALRAEFVQAIGFKFTIYKRNIEEPKILFPGHEQAK
                     AKTKNNNVTKKGKPTKRAVR"
     regulatory      58084..58190
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            58293..59498
                     /locus_tag="JAM15_03475"
     CDS             58293..59498
                     /locus_tag="JAM15_03475"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HAT6797331.1"
                     /translation="MKIAILGYGTVGSGLIDLIENNTSKRDIEVVGILVKNKEKHKYK
                     KYFDKITTDIEDIFDKDIDILVEVIGGLNPAFDYVTRALNKKIHVVTANKDLLAEKGS
                     DLIELANLNNVSIKFEASVAGGIPVLKPLIESLEGNNIKSINAILNGTCNFILSKMYD
                     ENLPYDVALKQAQELGFAEVNPDADVLGYDSARKLSILSTLSYGKIVYWKDLLLEGIT
                     SIDEKDIEYAKKLNCKIKLVARSKYESGEVSGFVRPALVDNNNMLSKIDNEFNVVILV
                     GDSVGELSFVGKGAGRGATGSAVYADIIDIIDNRSSNIKSFSKGKLDLSGLIEDECSA
                     VVRFGGYNNKDGILECLDKYVDSYDIIDDEELAIFVSAKSEHEIDRVLEIVKRNNYSE
                     SAKKLLKID"
     gene            complement(59699..60265)
                     /locus_tag="JAM15_03480"
     CDS             complement(59699..60265)
                     /locus_tag="JAM15_03480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAT6797332.1"
                     /translation="MATRPIEIDEYKKIMELLHTGFTYSENGVEKRFRKNPKVALALM
                     LEANLGLRISDILRLKIGNFKGNMLEINEKKTGKLQYRPVNKNIIESINEHARKYNLK
                     SNDYLVNIKTKAIQKQLRIICKHLNLYNISTHSFRKLYATTQFEKSNNNLELVKELLN
                     HSSVATTQRYIRVTQQAINEASENFFIG"
     gene            complement(60533..61792)
                     /locus_tag="JAM15_03485"
     CDS             complement(60533..61792)
                     /locus_tag="JAM15_03485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YlbJ"
                     /protein_id="HAT6797333.1"
                     /translation="MKKNKIIAFFAPAIIVGVLVLGIILYPNEAIKSAREGFSIWSNV
                     LVPSLLPFIIGANLIVDLKIVDIIGFIINPITRFVFNVSGKSALAFAISTVSGYPVGV
                     SLASEFRSNGQISKHEAQRLVSFCSTSGPLFIIGSVGTGMFQNSNLGYLMILCHYLGT
                     ILVGLFFRNYGNENLPKTKLDLKTNIKNVINIRNSSGNGFFVLFGNAVFNGVNTLLTV
                     GGFVIVFSVVFKILSLFNVISLIASVIYLPLSFLGVSKELCQAFVSGLFEITIGCNKV
                     SSITSSPEILRASLASFLIGFSGLSILAQCCTFLSKTDIDLKLYILSKFAHGVLAAIF
                     IFILYPIANSAVLVSSFADTYNVIYNNLIWFYYLSYYDTILQIVVIIYLISAVFIAKK
                     HMKTLSTNGKLMRYKNTFFIKKFSRKK"
     gene            61917..62630
                     /locus_tag="JAM15_03490"
     CDS             61917..62630
                     /locus_tag="JAM15_03490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HAT6797334.1"
                     /translation="MFNSIASKKVYEQVIEQIQYKILNGELKKGDKLLSERELSEQMN
                     VSRTSIREAIRVLETMGVIESRQGEGNFICTNIEKTLIEPLSMIFKLNNGTLEDILEL
                     RIILEIEIAKLASKRITSSEVIELKHIIDEMRVETNKKDNNRVLVLLDQKFHSKLATL
                     SKNYLIQSLFMTASKLFDGFIEDAREKIIAEPFNENILLKQHEAIYNAVIENDVELAC
                     EKAKEHMDFISKNYRKNEN"
     gene            62748..64022
                     /gene="larA"
                     /locus_tag="JAM15_03495"
     CDS             62748..64022
                     /gene="larA"
                     /locus_tag="JAM15_03495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-dependent lactate racemase"
                     /protein_id="HAT6797335.1"
                     /translation="MVKLKVPYSKQGMILEIPDERFLGVLESKSDNYIEHKTQEEIVE
                     ESMNNPIGSNSLEELVKGKKNVVIITSDHTRPVPSRITMPIILRRIRNVNPEIDVKII
                     VATGFHRPSTREELIYKMGEEIVDNEDIVMHISTDDKSMCKVGILPSGGDLYINKLAY
                     EAELLIAEGFIEPHFFAGFSGGRKSVLPGIASAKTIMYNHCSDFIDSDNSRTGKLNNN
                     PIHEDMVYAAKVAKLAFILNVVIDKDKKIIASFAGDVEKAHTKGCRFVTELSKVNSIK
                     SDIVVTTNGGYPLDQNIYQSVKGMTAAEATCKDGGVIIMISACNDGHGGQSFYENVAN
                     ADSPKQLLDKIRSVDRVDTIPDQWEFQILARILSKYTVIMVTDKCNPEMIKKMHMKHA
                     FNFKEALEMATSIVGKESKVVVIPDGVSVIVK"
     gene            64039..64827
                     /locus_tag="JAM15_03500"
     CDS             64039..64827
                     /locus_tag="JAM15_03500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009624503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HAT6797336.1"
                     /translation="MEILTCIKQVPGTTSVEVDETTGVLKRDGVDSKMNPYDLYALET
                     ALRIKEEKKANLKVLSMGPPQAKKVIEESFMMGADEGALISDRRFGGADVLATSYTIS
                     QGIKKMGKVDLIICGKQTTDGDTAQVGPEVAEFLDIPHVTNVTKLIEVKDESIVVEID
                     MPNDLQVCEIEYPCLITVEKDIFQPRLPSFKLKLNTKDREIPVYSLDDFEDKDENNYG
                     LNGSPTQVVRIFPPKPNTDKNIVRGNADELSFALVNKLEELKLV"
     gene            64841..66061
                     /locus_tag="JAM15_03505"
     CDS             64841..66061
                     /locus_tag="JAM15_03505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit alpha"
                     /protein_id="HAT6797337.1"
                     /translation="MSKIVVNQDKITDLKRILEICPFGAIEEKSGIVEISAGCKMCKL
                     CVKSGPKGAFEFIESSKVQINKDEWRGIAVYVEHHNGNIHPVTYELIGKAREMASKIK
                     QPVYCVFVGKDIKDKCSNLISYGVDEVFVYDEDEFKDFRIEPYSKAIENFIDKIKPTI
                     VLVGGTTLGRSLAPRLAARFRTGLTADCTILDIQSNTDLDQIRPAFGGNIMAHINTPN
                     NRPQFATVRYKIFSAPEKIENTTGKITLCKVEKKELKSKIKVLSVKEKNKEVGLEEAE
                     VIVVASRAIKKQEDMEMIYKLADKLNAQVAGTRPVIEAGWIDAKKQIGLSGRTVKPKL
                     IITCGLSGAVQFVAGMQGADYIVAINKDDKAPILDVAHLALIGDIYDIIPKLIEKIEN
                     NKDNNQKYMASAAK"
     gene            66072..67463
                     /locus_tag="JAM15_03510"
     CDS             66072..67463
                     /locus_tag="JAM15_03510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HAT6797338.1"
                     /translation="MYKLIDKKDIDFLIDTCGEENVLVGSDINEDFSHDELGGIEKYP
                     EVLVNVLETEQVSKIMKYAYKNNIPVTPRGQGTGLVGAAVAINGGIMINLCKMNKILE
                     VDYENLTLTVEPGVLLMTIGQYVQDRDLFYPPDPGEKSATIAGNINTNAGGMRAVKYG
                     VTRDYVRGLEVVLPNGEIINVGGKVVKNSSGYSIKDLLVGSEGTLGIVTKAILKLLPL
                     PKKSISLLIPFPDLSMAIETVPKIIKSKSIPTAIEFMERDVILAAEEFLGKKFPDNTS
                     DAYLLLTFDGNSTEDIEKEYEKVANLCLENGALDVFISDTQERNDSIWSARGAFLEAI
                     KASTTQMDECDVVVPRDKIAEFIRYTHELQDKLKIRIKSFGHAGDGNLHIYILKDGMD
                     DNTWKIRLKETFDYMYKKSRELSGQVSGEHGIGYAKKEYLHESNSDAYMMLIKNIKLA
                     FDPKNILNPGKIY"
     gene            complement(67726..69006)
                     /locus_tag="JAM15_03515"
     CDS             complement(67726..69006)
                     /locus_tag="JAM15_03515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HAT6797339.1"
                     /translation="MNILGLIVEYNPFHNGHIYHLSKSIEKTNATHTVAIMSGNFLQR
                     GEPALFDKYTRAKIAVENGVDLVIELPTLFACQSAEIFSHGAITILNSLNCINSICFG
                     SEEGNTEILYNIAEILANEPNEFKLLLKKYLDDGLLFPTARANALFDYIHQDKKNNFI
                     QNYSKEQLSKTLNSSNNILGIEYIKNLIHLNSSIKPFTISRVQSEYNSEEIESDICSA
                     TAIRTSLKENTDLFHLKNVIPEKTYNILNEKVDNGFLPMFDDFFFDILKTIILRDMDT
                     LKEYFEVNEGIENRIYKDIFTSEFLHELQLAIKSKRYTLTKIKRTLNNILLGIKKSDM
                     QLIKNIDTIPYIRILAFNDKGREILKEIKNKSEIKIINKFSNISFSLDDTIFKTLISY
                     DIKATNIYNSIYYKNNKDLVKGPMDFYTHPIYVK"
BASE COUNT        27134 a         7372 c        12690 g        21843 t
ORIGIN      
        1 ttaaagaaat tgtaggagga caatatatga aaaaaatatt agtagcatgt ggagcaggaa
       61 tcgcaacatc aacaatagtt tgtgacagag tagaaagatt ggttaaagaa aataatatac
      121 acgcagaagt tgagcaatgt aaaattgctg aatgttcaac aaaacaagaa ggtgctgatt
      181 taatcgtatc tactactata ctaccaacaa cttatgatat acctacaata aaggcaacag
      241 gatatataac aggtataaat acaacagcat tagataaaaa gatattaaat gcattgaagt
      301 agttttgtgt ttataaaaaa aatttagtat taaatataga gttgtatctt tataaaattt
      361 taaatataga gatatagctc tttttatgct gtttcaagta tacaactata tgatataaat
      421 cttcaatttt atgaaaaaga ttgttattac tttgtaagtt tataaaagat ttaaagttat
      481 tgttatgtta tactaattta tgggtatttt ttagaagtac tatatagaag tactaataaa
      541 ggagggattt aatacttatg ataaaacaat ttgtcaaata ttataagcca tataagaaaa
      601 tttttacact agaccttata gcagcttttc tattttcctt atgtgattta gtttatccta
      661 tgataactag aaatataatg gatgacgttg ttccaaataa aaacttaaga atgttagtag
      721 tttttgcagt agcacttata cttatattta tagcaaaagc agggcttaac tattttatgc
      781 agtattgggg acatgttatt ggtgtagata tgcaagctga tatgagaaat gaggtattta
      841 cacacttaca aagacttcca aatacgtatt ttgataataa caaatctgga gtaactatgt
      901 ctagaatagt aaatgattta atggatataa cagaacttgc acatcatggt cctgaagatt
      961 tattcatttc tatagtaatg ttggttggtt cattctttat acttatagat ataaatattc
     1021 ctcttacgct tataatattt gctatattac cgtttataat ttggtttgca atagctaaaa
     1081 aagataagat gaatattgct tttatgaaga gtagagttac tataggtgat gtaaatgcta
     1141 ctttagaaaa tagtatagca ggtatgaaag taactaagtc tttttgtact gagaaagagg
     1201 agttaaataa gtttgtaaga agcaataaat tatttagaag agcaagacaa gattcttata
     1261 aggtaatggc agaatattac tctggtatga atttatacat ggatatctta gagtgggtag
     1321 ctgtaatagc tggtggttat tttacttata taggaaaaat tactttgggt gattttgctg
     1381 cttatatact atatgtaaaa atgtttatac aacctatgaa aaaattaata aattttacag
     1441 agcaatatca aaatggtatg acaggtttta aaagattcat agagataatg gaacaagacc
     1501 atcaaaaaga agctaaaaat cctattgaac ttgaaaatgt aaaaggtgac attgagatag
     1561 aaaatatatc tttcacatat gaagataaga ctcaagtttt ggataattta agtttatcta
     1621 taaaagctgg taagactata gcattagttg gaccttctgg aggaggaaag actacattat
     1681 gtaatctatt gccaagattt tatgaatttg ataagggtga tataaaaatt gatggaaaga
     1741 gtataaaaga tgttagttta aaatcattga gaaaaaatat aggtatagtt caacaagatg
     1801 tatttttatt tacaggaact ataagagata atattctttg tgggaaccct aatgctacag
     1861 atgaagaaat gatagctgct gctaaaaaag ctagaataca tgactttgta gagactttgc
     1921 cagatggata tgatacttat ataggagaaa gaggtgtaaa attatcaggt gggcaaaaac
     1981 aaagaatttc aatttcaaga atttttttaa agaatcctcc aataataata ttggatgagg
     2041 ctacatctgc tttagacaat gtaacagaaa gagaaattca agagtcttta gaggaattaa
     2101 gtaaagatag aacaaattta gttgttgcac atagattgac tactataaaa aatgctgatg
     2161 aaatcatagt attgacggat aaaggaattg aagaaagagg tactcatgaa gagttagtaa
     2221 acaaaaatgg agtatatagt aggttacaca ataactagta tacaaatttt acaccatagc
     2281 taacatacgc attaaactta caaacatagg atatattaag attcataaag acaattcatt
     2341 ttatatttat gagatgtttt atgaataaaa tgtatcctat gttttatttt ttgcaaatta
     2401 catttaattc tctttgtaag aatagagtta aatagccaat ggtcaggata acgtttttac
     2461 aaaaagaata atttagaaaa ctaactttaa tttatggaat ttatcgaatt ttatgaaaaa
     2521 aatcgaattt tgacttgaaa tgtttttcaa aagtagtaaa ataatggata actatacata
     2581 cattttataa aaatacattt attatgaggg gggattttgt atggaggcaa taacagcttt
     2641 ttgtctagtt ttaatatcac tgacgatagg agatatagtt tcagcaaaaa ctaaagcttt
     2701 tgttccgtcg gtttttgtat cagcaattat atttatagta ggattctgga cttttttccc
     2761 agaaaatatt gtggacttag ccgctttagg aacaccatta gctcaattag gtatgctttt
     2821 gttaataact catatgggaa ctatgatgag tattaaggaa ttagcaggtc aatggaaaac
     2881 aatagtaata gccttggcag gaatagtagg aatatgtgta ggtgctttgg cattagggac
     2941 aatagtattt ggatgggata cagcagtaat agctacacct cctcttactg gagggctagt
     3001 tgcatctata atgatggcag atgctgctac agcaaaaggt cttgcaagtt tatcagtact
     3061 tgcaattttg atgtatgttg cacaaggatt tgcgggttat cctattacag cattaatgct
     3121 taaaaaagaa ggaaaaagac ttttatcaga ctttagaagt ggaaaagtaa ctgtaaatac
     3181 agatgaagaa aaagttaagg atttacctga acaaaaaagc agatttaaga taattccaga
     3241 cttaccagaa aaatatgata cgacatatat gataatactt agattaggat ttgtagcatg
     3301 gttagcagta caatttacaa atcttacaaa tgaagttgta tcaagatatg ttatatgttt
     3361 aatatttggt gtaatagcat cagaacttgg aatagttgat agaaaaccac ttaataaatc
     3421 tggttcattt ggatggttaa tgacatcatt gatggctttt atatttgcag gattagcaaa
     3481 agctacacca gcaatgcttg ttgaaatggc agttcctctt gtaggaatca taatatttgg
     3541 tgtaataggt atgggaatat tctctattat agtaggtaag cttttaggtg aaagtaaaga
     3601 aatggctttt tcagtttcgc ttacatcact ttatggtttt ccaccaaact atatattaac
     3661 tgaagaggca gtaaaggctt tggctgaaac accagaagaa aaagaatttt taatggataa
     3721 gatgcttcca aagatgcttg ttggaggatt tactacagtt acaatagctt ctgtagtaat
     3781 agcaggtatc tttgtaaatc taatatagta tttaagtgat aaaaagtatt ttaaataaga
     3841 agaatgtgta ctacttggag gtatggaatg gatattaaag aaataacaaa gagttataaa
     3901 gactatgtaa ttaagcttag aagggaattt catgaaaatc ctgagaaaag tatggaagaa
     3961 gttagaacat caaagagagt taaagaagaa cttgataaaa tagagatacc atatgtatca
     4021 gctggaggta caggtgtaat tgcaactata aaaggagcta atccaggaaa gactgtagca
     4081 cttaggggtg atatggatgc tctacaagtt gttgaatgca ctgatgtaga atacaaatct
     4141 aaaaatgaag gacttatgca tgcttgtggt catgatggtc acacatcaat gcttctaggg
     4201 gcagcaaaag tgttaaatga tattaaggat agtatcaatg gaactgtaaa attatttttt
     4261 cagccaggag aagaagttgg taaaggtgca agagctatga ttcaagatgg tgctatggaa
     4321 ggtgtagata gtgtgtttgg aatacatctt tggactgatg tagaatctgg gattatatcg
     4381 gtagaagaag gaccaagaat ggcttctgct gatttcttta aaattactgt aaaaggtaga
     4441 ggtggtcatg gttcacttcc tcatcaaggt gttgatgcag tgcttgcaag ttcagcaata
     4501 gttatgaatc tacaatctat ggttagtaga gaagtaagtc ctctggaacc attagttgtg
     4561 agtgttggag ttttaaattc tggaactaga tttaacgtaa ttgcgagtga agctgtctta
     4621 gaaggtacaa taaggctatt taatccagag cttagaaagc aaattcctgg aattttagaa
     4681 cgtatagcaa aatctacagc agaagcatat agagcagatg ctgaattaga gtatgggtac
     4741 ttaacaccag cagttataaa tgacaaagaa tgttcaaaga tagctacaga tgcagcaatt
     4801 aagctatttg gagaagactg tataacacta tttgaaaaag taacaggagc agaagattta
     4861 gctgagttta tgaatatagc acctggtgca ctagcatttg taggagctag aaatgagtca
     4921 aaaggtgctt gctatcctca tcatcatgga tgctttaata tagacgaaga tgctctagaa
     4981 attggaactg ctttatatgt gcaatatgca gtggatttct taaataaata attttaatat
     5041 actataaaga aaaagcagag actaagttta tatctctgct tttttattgt gtatattttt
     5101 tataaatatt gactatataa aatatatatg atagcataaa gaaaatgata atcaatatca
     5161 attaaaaaga aggtgattta tttgaataat gtaatatttg catttttgat aacattattg
     5221 gctggtttat ctactggtat aggaagttgt atagcatttt ttgctaaaaa aacaaatact
     5281 aagtttcttt ctataagctt aggattttct gctggtgtta tgatttatgt ttctatgata
     5341 gaaatttttc ctaaagcaca agatgctttg acaaaatcta tgggagagaa attaggaagt
     5401 tggtcaactg taatagcttt ttttataggt atggctatca ttgctgttat tgataagtta
     5461 attccacaag aagaaaatcc acatgaaata aagaaaatgg agaatataga agaaaagaat
     5521 atcaaaaaaa ataagtctct tttgagaaca ggtatattta cagcaatggc tatagcaatt
     5581 cacaattttc ctgaaggatt agctacattt atatcagctc ttgatgatgt tacaatagct
     5641 atcccgatag caattgcaat tgcaatacac aatataccag aaggtatatc tgtatctgta
     5701 ccagtttatt atgccacagg agataaaaag aaagcttttt attattcctt tttatctggt
     5761 atgtctgagc ctttaggagc gattattgga tatgtacttc ttagaaattt tttaaatgat
     5821 ataactcttg gaattgtatt tgcaattgta ggaggaatta tggtattcat atcactagat
     5881 gaattattgc catcagctag agagtacggg gaacatcatt tatctattta tggattgatt
     5941 gcaggaatgg gtgttatggc tattagttta ttactattta aatagctttt taaatatatg
     6001 attgtaacct aaaattagta tcaaaatgat ataattattt aaatagattt ttaagctatt
     6061 taaaaatatc attttggaga atgagtgcta tggaaaagaa aataaaattc aaatttgact
     6121 ggtatagttc acctgataag atagagaaat ggttagaaga tattgaagct aaaggatata
     6181 atttatataa gataaataaa tttggaggaa tattttattt tcataaggga agtccaagaa
     6241 aaataaaata cactgttgat tactactatg atgtagagaa taattatttt gatgaacata
     6301 aatcaaatgg ctggaatctt gtatttagga gtattggtag ttttatgggt acatctgcat
     6361 ggtatatatg gtcgaaagaa tacaaagaca tacctcctaa attatatagt gattctgata
     6421 aaaaaaacaa agtaaagtca attttattta tgaatatgtt tatattcttt atgttagtag
     6481 taatatttat atatttattg aatattgaaa taagaaattt atatagtggt tatggagcat
     6541 ctgtaactgc tattgtacta cagattatat tgttgatttt atatgcagta caattatata
     6601 ggagattaat gtattattta aggcttaaaa agtttaaata aataaaagaa ggtgtcctaa
     6661 aattattttt ttaatatttt aagacatctt cttttgttag taaagtactg tttttaatta
     6721 tagtaatttc tgtctttaaa ttgaaatatc aaataatagt tgtattggat tgagtattga
     6781 taaaaataat ttaaaaatgt tatcctaaag tatcagatat acaaaattat ctttaaatat
     6841 attataaata ttttaattgt attaactaga aattatgtaa ggaggcattt tatgattaag
     6901 atagcagttt gtgaagatga aaaagaaaca caacttttaa tagaagatta ccttgagaat
     6961 atattaaaag atataagtat agaatatgag atacaaaagt atatatctgg agaagagtta
     7021 ctggaaagta atttaaaaga tatagatata ttacttcttg atataaaaat ggaaaaatta
     7081 aatggaatgg atactgcaag aaagattaga gaagtagaca atgaaatgga aataatattt
     7141 gtaacttcat taatagatta tgtgcaagaa ggttatgagg taagagctta taggtattta
     7201 ctaaagccaa tagagttgga agaactaaaa aaacatgtgc taacttgtat caaagatatt
     7261 gaaataaata aggaaagtca tattacaata aaaaataagt ctaatacata taagatttat
     7321 ttaaatgaaa taaaatatat agaagttcaa aaaaaagata tgctaataca cacaataaac
     7381 aagaattttg atataaaata tagtttaggt aaaatagaaa aagaattaaa tccatataaa
     7441 tttataagat gccataaaag ttttatagta aatttaagat atgttgaaaa tataaagcct
     7501 aatgctgcaa tactggaaag tggagaagag gtacctatta gtagatatag atataaagaa
     7561 gttaaggaga aatttttaaa atttcttggt gatacaatat gctaaatttt atgaatgagc
     7621 tattagtagt tttatctata tttatacagt tttctataat gaacggaatt ttaatttata
     7681 aaaaggatag taaaaaaatg aaaaaatagt attctatatt gtcttgtttc ttatttatat
     7741 tataattcag ataagtagat tatttaatgg aggaaattac tttagtaata taaactattt
     7801 attttatata ttagcattta ttgcttgggg aggatactat aattattttt ataagatggg
     7861 ttatattaag tattccattt tcttttatct atttagtgta tattataaat gtttggatgc
     7921 tgttatatat agaatactat tttttgcaat tacaggtaat gttatttcat ctaaagaatc
     7981 cttattagta cctcacttag aatctataaa aattcagata tatagtaatt taataattat
     8041 tcttatatat cttatattta gcttttttag gaagtctata aaattaatta gccaagataa
     8101 gagaaattat gtatatttat tatttgcctt attagttaat acaatgaata tgcttgtaaa
     8161 ttatgtatta aaaaaattag aacggtttgg gtcattacat tcagaaggat actattttga
     8221 taattttgtt aatccaaagt tggtaggagc tagtagtata tttcttatat tattgtttaa
     8281 agaaataata aaagagaata gattaaaatc tcaagctgaa ttaataaaaa ataagttaga
     8341 tatgcaatat gcgcattatt taagtattca agaatctcat atgcgagtta agaaactata
     8401 tcacgatata aataaccaca tttattgtat agacaacctt agaaacaata gcaaagaaat
     8461 taatgaatat gttaacaatt taaaagatga aataaaaaca tttaaatata tctataatac
     8521 aggaaatatg atattagaca ttataatcaa cgaaaagagt gaaatatgtt taaaaaaagg
     8581 aattaaattt acttgctcta taaatttttc aaaagtaaat tttgtaaaac ctatagatgt
     8641 gtcaagcata ttttctaata ttttggataa tgcaatagaa gcatgtgata aaatagtgga
     8701 tgaaaatatt aataaatata ttagaattaa aggaactata acaaggtcat tttttgtact
     8761 taaatgtgaa aatagtaaac taaatcagct tacttttaat aaaaatatat tgttaacaaa
     8821 caaaatggat aagttcgtac atggaatagg tattcagagt attaaatctt ctttacaaaa
     8881 atataatgga gaattattat ttgaaaatag tatcgataaa tttatactaa atatatatat
     8941 accattggag caagatactg acagttgggg cgattaagtt accagttggg acatatgtat
     9001 tgatacaaaa aaataaggat gttatctttt aataacaaaa gataacatcc ttatttctgt
     9061 attaaggagc ttataatttt actaatagta agttataaga attggatagg aaggtgatat
     9121 gtattgaata ataaatcttt aatataaaga aaatataaat atattctagt gcaatgaata
     9181 atactttaga gcggttagtg tgatgggagg attgtgtatg aaagtaaaaa ggaatataaa
     9241 tagagtggca ataattgtgg ctttaaatct tagcttagca ttgatggcag gatgtatgtc
     9301 tcctgtatct gataagaact taagtagctc agaacaaatt agtaaagatt cattgaaaga
     9361 acaagttgaa gataaaaaag atgaatctat cgagctattt aataattact cacaaaagat
     9421 taatgatgcg aaaggtagag aagaagtaaa aaaagattta tctcaaagat tttcgaaagc
     9481 tataatagac agtggttata gtattattga ctcaaaatca gatggtagct ttgtagtatc
     9541 tataaatggt gctgaaaaac cacctgaaaa aaatattcga agtttattct attctatgtc
     9601 tgaagacgat aaagaaggaa aagtaacaat agatattctc tgtgctaaag agtatccaga
     9661 agatgataag ttatctgaga gtgataaata tattaaattt atatacaatt tatttaaatc
     9721 attgactaat acgaacttaa ctgagaaaga aattttttct atggttgaag aagaatttaa
     9781 taagggagta ggtgttgtag agcttcctta tatgaaggat atacatgttg aagttaacaa
     9841 agttaaacaa tcaactaagg ttttaaaact aagtctagta tacaaatttg atatttcaaa
     9901 tcattagtat attagaaata actataacaa tatagaaaat atatcataga aaattttttt
     9961 agattttata aatttaacaa aaaaagtatt aatatatagg tgttcaaggt agatgaaaaa
    10021 aaataagtta ttttgcttcc attttatgct aaaggacagt ataatataat taaagtatgt
    10081 tataacatac aaaaatgtag tatatattat ccaaaggggg attttaaatg agtcaaacta
    10141 atagaataga agcatttaga caagaatata ttaattctaa acctatgata tgttgtgaaa
    10201 gggctagaat ttttacagaa tcacataaaa aaactgaggg agaagctatc tgtataagaa
    10261 gagctaaagc ttttttggag acatgtaaag aacttcctat aaaaatcttt gaaaatgaat
    10321 taatagtagg tacagcagga aaatttagaa gaacagggat attgacacca gagttttctt
    10381 ggcaatgggt agacaaagaa atggatactt ttgataaaag aactcaagac ccatatataa
    10441 tatcaaaaga acaaatagaa tttataagaa aagaaatatt tccatattgg aagggaaaat
    10501 ctttggaaga agttttctta gcaagaatcc cagaagatac agctaagata ttagtagata
    10561 caggaataat agataatgat tctaagtgga gacaggcagt tggtgaagta acaccagatt
    10621 atcaagatat attgtttgta aaaggatata aagggattaa ggaagatgca gataaaaaaa
    10681 ttaaagaatt agatatatca gtttcagaaa atattgaaaa gatagatttt tacaaatctg
    10741 tttctatagt tgcagagggt attatgacat tggcacaaag atattcaaat cttgcaaaag
    10801 agatgagtaa gcaagaaaca gatgaaaaga gaaagttaga acttataaaa atttcagaga
    10861 tatgtatgaa tgtaccagca aaccctccaa ctaattttta tgaagcaata caatttgtat
    10921 ggtttgttca attaggtggt attctatcag aaaatccatt ggcattaaat ttaggtagat
    10981 ttgaccaata tatgtatcca tattatgaaa atgatgctag agaaggtaaa ataactgaat
    11041 cagaagctca agaattgata gaagcacttt ggattaagtt atcagaatgg gtatggacta
    11101 tatcagcaaa tacagcaaat tactttgcag gatataatca attccaaaat cttactgttg
    11161 gtggtaaaaa gagaaatggt actgatggaa cgaatgatat ctcatatatg tgtttaaagg
    11221 ctacagaaag tgtaaaaact caccagccag gattaagtgt tagggtgagt caaggagcac
    11281 cagataattt cgtaatggca gttgctaaat tggtaaaaca aggaactggt ttccctgcta
    11341 tacacagcga tagtgcaggg gcacaaatgt tactacaaga tggatatgat gcagaagatg
    11401 ctagagattg gagtaactgt ggttgtgtag ttcctcattt tagaaaaaca ggacagtgga
    11461 cttcagccgt aaatatcaat tttgcagcag ctttagaata tgctatgaat gaaggtaaga
    11521 gtagattaac tggagaaaaa atggggttag atacaaaaaa tatcacagaa tttacttctt
    11581 ttgaagaact taaggatgag tttttaaaac aattagcata tcttgtaaaa agttctgtta
    11641 taggaactac tgttgctcaa caaattcata aagaaatggt accaagacca tttttatcta
    11701 cttgtgtaga tggatgtttg gataagggag ttgatttaag taaaggagga gcaaaatata
    11761 atataggtcc tgtattaact ggtatagggt taggtgtagt ttcaaattca ttggcagcta
    11821 taaaaaaatt agtatttgag gataaggtga ctacgttaga agaattaaca aaagcactaa
    11881 ataatgattg ggaaggttat gaagaattaa gaaaacttgc gttggatgtt cctaagtatg
    11941 gaaatgataa tgattatgta gattcattag caattgaagt ttctgatttt tattatactg
    12001 aaactagaaa atacaaggat atttttggct ctaaatttaa tagtgcattt atgggtatat
    12061 caaactatgt accaactgga aaaatagtag gtgcaactcc ttgtggaagg aaagcgacaa
    12121 aacctttgac agagggagtt tctccgtttg ttggtactga tacaacaagt ccactagcag
    12181 ccatgaaatc tgcatcaaaa ataaatcatg atgttcatac tggtggaaca cttctaaatt
    12241 taagactgaa tcaagatttg gtggaaactg aaagaggact tagaaatcta acatctatga
    12301 ttaaatcata ttttgcttta ggaggattcc atgtacaatt taatacgata tcaaatgata
    12361 ctctattaaa agctcaagaa aatccagaag aatataaaga tttattagtg agagttgctg
    12421 gatatagtac tcaatttgtt aatttatcaa gagaaatgca agatgctata atagctagaa
    12481 attcacatag caatttttaa ttatgaggta gattatgagt aaaaaaggta gagttgtaaa
    12541 agtacaacat ttttcagtaa atgatggaga tggaataagg actactatat ttttagaagg
    12601 atgtaaatta aaatgtaagt ggtgttctaa tccagattcc tggagtaaca tagtaaaatt
    12661 aggtgttatg aaagataaat gtgtatcctg taatagatgt atagatgttt gtcctcaaaa
    12721 tataagttca ctatttgata gaacgcaaat aaataataaa tgtgatttat gtggagagtg
    12781 tatcaaggta tgtcttaaag atgctatttg tataatgacc aaagaaatga gtgttgaaga
    12841 aatagtagag gaagttgaaa aagattttat atttttcttt gaatctaatg gagggataac
    12901 tttttctgga ggtgaaccta cacttcagat tgatttttta agagaattag ttgatatttt
    12961 ttatgataaa ggcataaata ttgcaattga aacttgtgga tattttgatt ggaataaggt
    13021 aaatgatgta tttgagaaaa tagaccacat atttgtggat ataaaatcta tggatgataa
    13081 tattcataaa gaatatacag gagtaagtaa taaaattata ttagataata tatgtaggct
    13141 ttcaaagttg aataaatcta tggttataag agtgccaatt atttatggtg taaatgatag
    13201 tgaagaaaat ataagaaata ctgcattatt tgtcaaacaa aatgttccag gaggcaagat
    13261 ggagttactt ccatatcata aatttggaat cgataaatat aaggcattag ggcttgaaga
    13321 ttatatatat gaatttgatg aaatttgtaa caatcatatg ttaaaattaa aagagatagt
    13381 agaacttaca ggagtaaaaa tcatagaata caaatagcta tcaggaggat tttaacatgg
    13441 ataataaatt tcctaatgtg ggagaaaatt taaggttatt gagacaagaa atgggcataa
    13501 gtttagacaa agcttcaaag atgacaggtg tcagtaaagc aatgcttgga cagattgaga
    13561 gaggtgaatc aagtccgaca gtatctactt tatggaaaat ttcatctgga tttaaaataa
    13621 attttactac actattaaat gaaaatacaa atacctatga ggttataaaa aaagaagaag
    13681 tagagcctat tgttgagcaa aaagggaaca tgaagttata tccaatatac ccttttagcc
    13741 ctcaaagaag gtttgaactt tttataattg agcttgagga aaactgtact catgtttcat
    13801 ctacacatag tcatgtttta gaagagtatg tactcgtaat agaaggtaaa cttgacctta
    13861 atgtggatgg gaaaacttat attttagagt ctggacattc tattaggttt gatggaactt
    13921 tagagcatat atataaaaat ttaaataaag gaaaaactat atttcacaat atagaggttt
    13981 atagataatt ttatagttat ccttttctaa aataaatgaa aattttagaa aaggataact
    14041 tatttttata atgtcgaaaa gatttatatg tatgtgatga tgttattgtt aaaaaaaaaa
    14101 cataaaagca ttataataat attaacaaaa tagaataaag aggaagagaa tatgattata
    14161 aaggtttcaa tgacagtatt agtattaata ttattgtata ttctgtataa gtatgaaact
    14221 cagcatatag aaacgacaga atataatatt ttcaacaaaa aaattccaaa ggaatttgat
    14281 aactttaaaa tagttcaagt gagtgattta cataataagg tgtttgataa aaataataag
    14341 gtattgatag ataaaattga atcattaaac ccagatgtta tatttataac aggagattta
    14401 gtagatggag aaaataaaaa ttttcaagtt gcattagatt taatagataa tttggttgaa
    14461 aaatatgaag tatatcatat aattggaaat catgaacaaa agtctttaat aaaaaagtat
    14521 aaacatctat ataaggatta ttttaaggaa ctatattcaa agaaaataat aaatatggaa
    14581 aatgaatctg taagaatata tagaggtaat agccatctta atttatatgg tttaattata
    14641 ccattggaat gctatccata tttatttgct aataacaaaa aattagaact aagtgacaat
    14701 tttgtagaag acaatctagg taaagttaat gaaaatgaat ataacattct tttagcacat
    14761 acaccatttt tctttgaaaa atatgcaaaa tggggagcag atttggtttt agcaggacat
    14821 gttcatggag gtataataag aatacctttt gttggaggtg tattatctcc aaatagagag
    14881 ttctttccta agtatgactg gggaaaatat gaaaaagata atagcactat gattttaaat
    14941 aaaggcttag gaggctcaaa agttttaatt aggcttaatt gtaaaccaga gatagttaag
    15001 attacattga agtatgagaa ataagatttt atataacata tataaacatc aataacatat
    15061 aaataaggtt gatgttaaat ccatttaaac atatataatg accaattttg aataattgtt
    15121 gaattaataa aaataaagtg ctatttttag catagaatat ttaaactatg gggggtagta
    15181 aagaatcatg ggtgatacaa gtagatttta tgagtctgta aaaaataaat atccgaaatt
    15241 aaaagatgga actagggttc atctgtggcc aaaagaaaac attataattg gtcctattta
    15301 tgatgaagaa gatggatata aaaaaagtat cggaaatgtg gatagcttaa gttggaagca
    15361 aattgttata ctggctgaat gtgatgggaa aaatactact gacgatataa taaatatatt
    15421 atccaataga tatagaaata tccataatat gaaagaaaaa gttatggaat tttttatgtt
    15481 ttatgagaat gtatacttaa cgtttgaaga tgatatacag acactatcaa gtgtatttga
    15541 gataacagga aataaatcat acattactcc tttgtacttt actatagaaa tagatggaga
    15601 taataataca aatgattatt tttctgaaat cacaagttta ttgaactgca tgtatgagaa
    15661 aggctgtaga tttatagagg ttattggtga ggatatttta aaaaataaaa gtatgagaga
    15721 aatatttcaa tatatgttag accattttga tttaattgtg gtaactaaag atagctttac
    15781 tattgataga agcttaataa aagaattaga taattatcgt cataaagtga tatggaaagt
    15841 atattcaaaa aatgatgata cacgtattaa attaaaagaa gatataaaaa taaccagttt
    15901 aataaaaagg ggtcacactg tagtaagagg agacagagaa aaagcaataa aaatagaaga
    15961 tatgaggttt aaagatacaa aggagaggtt ttcaaaatat ggagcagagt ggagtcattt
    16021 atatatttct tctgatggta gtgtaaaatc ttattcattt caaaaagata aaagagtcta
    16081 tttaggcaat atatttaaca attctgttga agaaattttc ttagagatgc aaaataaaat
    16141 tgacaaacta gaaattgtgt atcaataagg gtaaagttta agatttatat aagatttata
    16201 gattgtttat ttaagtttgt gtcaataatt ataatgaggt gaaatgactt gttaaaatta
    16261 ttggacaaat ttttttatga tgttttactt aaattttggc tgtttatgat gctgtggatt
    16321 tttagagaac tttttacaaa ttttaaaatg actaaaaaat ttaaatttca taaaatattt
    16381 atgtaaaaat catataaaat tcatatagca tatgtatcat atgaggtgta gaaagactag
    16441 cttaaaaacc ataatataat accctattgt aatgataacc ctccctcaca tcctcaaata
    16501 gagttatcat tacaagaatt aatccataaa tttaaaattt atggtttttt tttatttaat
    16561 ttgttttatt atattagaat atgatttatt atagaatata taataagtaa tatagaatac
    16621 attaattaag tttttgacat gtaactatac taataaggag gagtatttat gaatgtaaat
    16681 aatcacaagt gcccagagtg tggtgaacat agtaaaaagt ttgaaatagt agaggaaaat
    16741 gaggattgtg taatatttga atgttacact tgtggaacta tatctatatt aaagtattgt
    16801 gagaactgta aagaatttgt atttgtaaat attccaaata atgtggagac atatgagtat
    16861 tgttgtggaa aatgtaataa taaaatttaa tataatataa acatatgtaa tttcatatat
    16921 catttatacc aatctcatat aaaattcata tataaaatgt attatataaa tatagaaaga
    16981 actagcttaa aacataatat aattacccta aatttataat gacaactctc cctcacatcc
    17041 tcaaattata gttgtcatta tagaataact tggctgtttc aaaaatgtga aatcatttta
    17101 gaaacagctt atttttttat aaaaataaag aaggcaacgg gaagccttct ttcgtgtaaa
    17161 aaaagtttaa ttttttgtta agatttgttt gttattttat attactttta taatatgttt
    17221 ttatttggtg gttggcaatg gattttgcac aactggtcat tattaatgta aaagtggaat
    17281 attattaata aataataatt acaaaattgt aatctttatt tattaaataa atgagtaaaa
    17341 taatatatta atgggtatat aattaagaca atactagttt ggggaggata aaattatgga
    17401 ttataaaaca atcatattaa atagaaagtc tgttagagaa tataagaaca tagatattaa
    17461 agaagaatat cttagtgaaa ttaagaaata ctcagaatct tgtaagaaac tagttccaga
    17521 aatagatgtt gatgtaagaa ttatgaataa aagtgaagtt tttaataatt tagataaagt
    17581 agcagggtac aaaggaaata tgatagattc tccaagttat attataatat tatctgacat
    17641 aaaagataat tacattgaaa attcagggta cataggagaa agtataatct ttaaagtaac
    17701 agaacttgga attggttctt gttgggttac ttttgaagat ggaaaaaagg taaaagaaaa
    17761 acttggaatt aattcagata aagaggtaac aggaattata gctattggat atggagaaaa
    17821 tgtaagtaat gctaaagtat taaatgctac aaaaactggg caaaattatt caaaatctga
    17881 tatgcaagtt gtaacagata aggggtctac tagactaggt gtagaagatg ttgtttatat
    17941 gaacgaatgg ggaaatgttg caagtataga aatcttagaa gaaagagcac ttcttgatgc
    18001 atttcactat gcaagattag ctccatctac attaaataga caaccatgga gatttatagt
    18061 tgatggaggc actgtagttt tagctgttag aaaagatggt catactaatt tatatgaaga
    18121 aaaaatagac attggtatag ttatgcttta ttttgcaaca ataataagtg caactatgtt
    18181 tgatttaaaa tggaatttag gtactccaga caaagattat aaagtgccag aagactataa
    18241 gatagtagga tattgtaata tataagatag tttaatactt aatttaacta cacttaaatt
    18301 aatttttata aaaagttcaa taatatttta taataaaatg ttattgaact tttttattgt
    18361 ataatacaat ttttatattt attgtattga ttgaaaaata cttatgaatt taaatgctta
    18421 caattttgtg catgaataga gaggtatatt attttattaa actgtataat ttgcttggag
    18481 gtaatatcaa atggaatgga taaataaatt aaatcaagct attacttata ttgaagaaaa
    18541 tctcgaaagt ggagtggatt atgcagaagc agcaaaaatt gcatgttgtt caacctttca
    18601 ttttcaaaga atgttttcat atattgcaga agtaccatta tctgaatata ttagacgaag
    18661 acgtatgact aaggctgcat ttgaacttca gaacagtaac atcaaaattt tagaactatc
    18721 tgagaagtat ggttacgatt caccaacatc ttttaataga gcttttcaaa atatacataa
    18781 catttctcca tctgcagcta gagcaaaggg tgttgtttta aaagcatatc ctaagatgac
    18841 attaagcatt tatgtaaaag gaaatgtaga aatgcaatat cgtattgtag aaaagaaagg
    18901 gtttcgtatt gttggtataa aagaaagtat gaacatgatt gtagaagagt gctttgagaa
    18961 agttcctaag ttatgggcta aatgcataaa aaatggaaca attgataaac tttcagagtt
    19021 aataaataac gaaccttgtg gattgcttgg agttagtgtg tgtacaaata gtaagggttt
    19081 agattattat attgctgcac caacagataa gcctgtatta gaagatactc gtgaatactt
    19141 aataccatca ggtacatggg cagtatttga atgtgtttct ccaatgccaa atgctctggc
    19201 aatacaggaa ttgcaaaaaa gaattattac tgagtggtta ccaagttctg ggtatgtgta
    19261 tgctaactta ccagatattg aactttatcc caatggcgat atcaatgctc ctgattatac
    19321 tacagaagtt tggattccaa ttcagaaacc aagttaaagt taatgaataa cattaaattt
    19381 aataaacaac atgaaatttt aaaattacag gctgaaaata gtctgttatt tttttgtaaa
    19441 tatggaaagc aagctttaca taaatgaaat atagttgtat aattatggaa agtaagcttt
    19501 ccgtagttga gatattaaag ggggatagat gtgaaaaata gattagaaga aataagaaaa
    19561 gaaagaggta taaaacaaga agaacttgct tctattttgc aagtatcaag acaaactata
    19621 ggttcattag aaaatggtag gtataatcct tctatcatct tagcctttaa gatagctaga
    19681 tactttgata tgaatattga agaaatattt atttatgagg aggagtaaaa atgaaaaaga
    19741 atatgttata tgttggaatt atatatttta tttgtggaat tttacttgtt ttattggcta
    19801 catttactga gttttcattt gaggctttta tttggggatt atctggagct gctttaggtc
    19861 caggtgtatg tatgattctt caatatatgt attggagtaa acctgaaaga gcagtagatt
    19921 atgaagaaaa gataaaaaat caaaggatag agatgaatga tgaaagaaga attatgttac
    19981 gtgataaagc tggacgtatc accaatcaaa tcatgtccta tgttcttgta attcttatat
    20041 ttattgtttc tatattgagt gtattttctg taatggtaat aagcaagtgg gttttagttg
    20101 ttcttggatt acttatttta tttcaattta tttgtggtgt tgttgtatac aataaattag
    20161 ataaaaagtt gtaataagtt atgatataaa atagaaaatt atataaaaat aaattagttt
    20221 ttaaattaat gctagaagat aaatttatat aattatataa attttaaaaa gacacagtaa
    20281 tttcaaaaaa taacttaaaa tttaaatcaa aaataaaaaa actcctaatc tattgaataa
    20341 atagctttag gagtttttaa tggtgcccga ggccggactc gaaccggcac ggagtattag
    20401 tccggtggat tttgagtcca ctgcgtctac caattccacc actcgggcat gtcatgtata
    20461 ttattatagc aaaaaaatat attgtttgca acatatttaa ttttaatata ctattattat
    20521 tatgggaata ttaaataaca ctatattggt atataatata tatgttacaa aaatagataa
    20581 tttttaggag tgatataatt tggaaaaaaa attaattata atagatggaa attcaataat
    20641 aaacagagcc ttttatgctc tgccagaaat gaataataaa gaagggttaa agaccaatgc
    20701 aatatatgga tttacaacaa tgctatttaa aatgatagat atatataaac caacacatat
    20761 aagtgtagcc tttgacagaa aagcacctac atttagacat ttagaatata aagagtataa
    20821 ggctggaaga aagggaatgc cagatgaact ggcagaacaa ttacagccat taaaagacct
    20881 tttagataaa ttcaaaataa atagattgga aatagatggg tatgaggcag acgacattat
    20941 aggaactgtt tctaaaaaag cagaaaataa tgggtataag gtatacatag taactggaga
    21001 caaagatgct attcaacttg cttcagataa tacaactact cttataacaa aaaaaggagt
    21061 tggagaagtt gaagaataca actttaattc tgtaattgaa aaatacgaga tgactccagc
    21121 acaatttatt gatttaaaag gtcttatggg agataagtca gataatatac ctggagtacc
    21181 tggaatcggt gaaaaaacag gtataaagct tataaaagag ttttctagta tagagaattt
    21241 aatagagaat acagataagc ttaaaggtag tgtaaaaaag aaaatagagg aaaataaaga
    21301 aatagctatt caaagtaaaa gacttgcaac aattataaga gatgtgccaa tagaagtgga
    21361 tttagatagt atggtttttg gcgattatga taaagatgaa cttttagata aatttagata
    21421 ctttggattt acaagtctct tatcaagatt agttgatttg gtcgattcag atgacacaga
    21481 acacgtagaa gaaaaaatag aaatattaaa attaaaagat acagaaaaat ttatagatga
    21541 agtaaacaaa aaaggacaag ttattttaaa aactgttaga ggacaaggta atatacttga
    21601 aaaaaatata atatatattt ttataagtgt agatggagaa aaaatatatt atgtagattc
    21661 aaatgaagtg tcaaagttag atagtatatt ttcaaataat gaaattaaaa agtatggata
    21721 taatttaaaa gatgattata tatctttaaa accatataat ataaacttag aaaatatgta
    21781 ttttgatata acaatagctg agtacttaat agattcaact tcatctacct catatgattg
    21841 tagtgcaata gctatgaagt atttatcaaa aaaggttaaa tcaaaagaag aattattagg
    21901 aaagggtgtt aaatctaaaa actatgagga tttagaattt gaggatttag cagagtatat
    21961 gggtcaaata atatgcacag ttaaagaaac aattcctatg atggaaagaa gtctaatgga
    22021 tatgagtatg gatggtcttt tttatcatgt agagatgcct ttagtagaag tcttaggtca
    22081 tatggagtat gaaggtataa aagtagacaa aagtatattg gatgaattga gtgtagagtt
    22141 taaagaaata atagctacac tagaaaagga aatttatgaa ttatcaggag agccattcaa
    22201 tataaattca ccaaaacaat tgggtgttat attatttgaa aaattagagc ttccaataat
    22261 taaaaaaact aaaactggat attcaactaa tgcagatgtt ttagaaaaat taagagataa
    22321 gcatccaata atagataaga taactgagta tagacaaata gtaaagttaa attctactta
    22381 cgttgaagga cttttaaata taataaatcc agaaagtaat agaatacatt catcatttaa
    22441 tcaaactata acgactacag gaagaatttc atctacagaa ccaaatcttc aaaatatacc
    22501 tataaaaatg gaaatgggta gaaaaataag aaaagtgttt attgcagatg ataactgtaa
    22561 gttggttgat gccgattact cacaagtaga gctaagagtt cttgcacata tgagtcagga
    22621 tgaaaatatg atagaagcat ttaaacatca tgaagatatt cataccaaaa cagcttcaca
    22681 agtttttaat gttcctatgg aagatgttac tagtgaattg agaggtgcag ctaaagctgt
    22741 aaactttggt attatatatg gtaaaagtga ctttggtcta gctgatgatt taaatatacc
    22801 tgttccaaag gcgaaagaat atatcgaaag ttattttgct aaataccata aaataaaaga
    22861 gtttatggac acaacagtag aaaaggctag tgaggatgga tatgctgtaa caattttaaa
    22921 cagaagaaga tatataccag aaataaagtc aagcaatttt atggaaagaa atagaggaaa
    22981 gagatttgca atgaatgcac caatacaagg aagtgcagca gatataataa aaattgctat
    23041 gataaatgtt cataaaaaat tggaagagaa caatttgaaa tcaaaactta tactacaagt
    23101 tcacgacgag ttgatagttg aagcaattga tgatgaaata gatatagtta agaaaatagt
    23161 aaaagaagaa atggaaaatg ctgtaaatat ggatgttcac ttagatgtag atttaaatgt
    23221 aggtagttct tggtatgaga caaagtaggt gattttatgt tgatattagg acttacagga
    23281 ggaataggct gtggaaaaag cagcctatca aatatattta gaaatcttaa tatttctata
    23341 ttggatgctg atattatatc caggaagata tttgaggata agttgttatt ggaaaaagta
    23401 tttgtccatt ttgggcaaag tataaaaaat gatgatggaa ctctaaatag aaaagctctt
    23461 gggaaaatag tttttagcga tgaagaaaaa cttaaggaat taaatagctt gactcatccg
    23521 cgaataagag aaaaaataat aagtgaaata gaagaattga gaaaaaaagg cgaaaatata
    23581 gtagtattag atgcagcaat attggtagaa agtggttttt tagatatggt tgacaagcta
    23641 ttagtagtta cttgcaaaca agaagtacaa attagtagaa tacaaaagag agataattgt
    23701 agtaagcagg aagcacttag taggataaat tcacagatga gtcaggaaga aaaatccaaa
    23761 tatggtgatt atataataga taattcggga acaataactg aattagaaag taaagcacat
    23821 aaatttattg agtacatgaa ggagaattgg cgtgaatagt aagaaagtat tgattctatc
    23881 tatttttata atcttatttg gggcactatt aatggaaagc aaagtaatac ataaattttt
    23941 atatcctaaa aaatattcag agtatgtaga aaagtattca aaagaattta atttagatga
    24001 aaatatagtt tacagtgtta ttaaagccga aagtaagttt aatagttctg ctgtttcaaa
    24061 aaaggaagca aaaggattaa tgcaaatatt agatataact agagattggg gagcagagga
    24121 actaaattta aaaaatgtgg atattttcga cccagagact aatataagac ttggctgttg
    24181 gtatttaagt aagttataca aagaatttgg taaattagat ttagtgatag ctgcatataa
    24241 tggtggttca ggtaatgtga aaaaatggtt agaaaataat gaatatagta aagatggcga
    24301 aaatctacat gatatacctt ttaagcaaac ttcaaaatat gtagaaaaag taaaaaataa
    24361 ttacgaacat tataataaga tatatggcaa gaaaggaaaa aactaatgaa gagaataaaa
    24421 gtcttaacag tcgttttagc tataactctt atggtagctg gttgtagtaa tactaaaaca
    24481 aaacaaagta gtagtgattc aagtttacaa agtcaaagtt ctatagatgc taagtatata
    24541 aacttaacaa tggtaactcc aaaaactata aatcctataa ctaatactga taagtctgtt
    24601 ggttatataa tgaatttagt ttatgatagt ttatttacta tagatgagaa ctacaatgta
    24661 attcctcaat tagttaaaga gtataatata gctcaggatg gaatgagtat agatataaag
    24721 ctaaaagatg caaagtggca tgatggaaaa aatgttactt caaatgatgt aaactatact
    24781 attggtttaa ttcaaaaaag tgcagatagt ccatataatg aatttactaa aaatatagct
    24841 tctgtgaata ttaaatcaga taaagatttt acaataaaat ttaaagctag atatgctttt
    24901 tcaattgata gtttaatttt tccaatcgta tctcaaaatc atttagattc aaaggatgta
    24961 aatgacaaga ataataatat gataggaaat gggaaatata aaatagaatc atatacagaa
    25021 agagaaggaa tggttttatc tgtaaacaaa gattactatg aagaagttcc aaagaccatg
    25081 aagaacataa aagtaggtat ggtgcctaat gaagaggcaa ggacatctat ggttatggct
    25141 cttgatagtg atataaccaa tgttacatta aatgatttaa gcaagtttca agaaaaagag
    25201 tttaatataa caaaatatca aggaagagat tatgagtgtg tattatttaa ttataataat
    25261 ccatttttta aagatgttaa ttttagaaaa gcaattgctc actctataga taaagataga
    25321 attattagtg aaggttatat ggatgatgct actccagtta attttccact taattcaaaa
    25381 tcaaaatact ataatagtga aatgaaggat ttagagttta ataaagataa ggcgatagag
    25441 tgtcttgcta aggtagaata tgcaaatata aactcagtaa atcaaaatga caataaagta
    25501 aaaaatcaga aaaaatcagc taaaaagaac tcaaagaagc ttacgccaga agaagaagca
    25561 aaagctaaaa aagcagaaga agatagaatc aaaaaagaag ctgaagagaa aaaaaataga
    25621 gaaaaagagg aagtaaagaa aagtctttct gaaatgaact taaagataat agtaaacaga
    25681 gataatagtg agagaataaa aactgcaaac ataataaatg aaaacttaaa agctatagga
    25741 ataaatagta cagtaaatca gctgtcagat aaggatatgg aaaatgctct taattctaaa
    25801 aattatgatt tagcattagt tggatggaaa ctatcaatta taccagatgc aagtagtatt
    25861 atagcaagta gtggatatac tgatgataag ctaaatggat atatgtctgc acttacaagt
    25921 tctacgtctg aaattgaaac aaaaaaagca tacaaagatg tacagacata tataaaagat
    25981 aatgcaacat ttataagttt agctgtgaga aacaactata ttgtaagtaa tagtagatta
    26041 aaaggtaaaa ttactccaaa tgattttgat gtatatgagg gaatatctaa tttagatata
    26101 aaatcgaatg aatcaaatta aatgattaat ttctatttaa aaagtataaa ctatatgata
    26161 gaataccctt atagggtata aggaggtaat taaatgaaga agaaactatt agtagaaggt
    26221 atgagttgtg gtcattgtgt aaaccatctt aaaactgcat taacagaaga tatagatggt
    26281 attgaagttt tagatgtgga tttagaaaat aagtgtgcat ctgtagatat gaaagatgat
    26341 gtatctattg aaaaattaaa agaagtgata gcagaattag gatttgaact aaagggaatt
    26401 gaatagaaat tgataaacta aaaaaaggcc tctattgggg gagtaataga ggtctaaaaa
    26461 tgggggagat tgagtatgtt tgattttaca ttactattat ctcccctttt aaattaatat
    26521 atacataaaa agtaaaaaaa ttttgtaatg actcacattt cttgagcttt ttgaatatac
    26581 tataaatagc taagggaggg agtatcatgg aatctagggg atataaagag gatttaaaaa
    26641 aaatgatact tgatatggcc cacaaagaac ttgagagtta tgtatcacaa aaaggagcaa
    26701 aaaaatactt tgaaggtaac ttggataaga ttattaataa taatataaaa aaattcaatc
    26761 aaagtattgg tcttaataga gtatatttaa aaatgttaaa aaagtgtgca tatcaagaaa
    26821 gtgtaacttc aatatcaagg actataaaga aagaagcatt atttaaatca aaaaaagagc
    26881 tatttgcttt ttcagagtac ttaaaacttg atattaacaa gcgactttca tataatcaaa
    26941 ttttaagaaa aatatcaaga tatatatact ataatagaag ttcatatgct caaaaatacg
    27001 ttgttttcaa aagaggagat gaagaatatc ttttagaacc agagaaaata aaagatgaat
    27061 taatatcaag ctataggtca aagactagag aagatatgag gtcaatagca aaacttttgg
    27121 atatagaagt agaagatgat tataatgctg aagatattag aaaaaaagta ataaattata
    27181 ttatcaaaga aaaacttaaa agttagagtt ttaaagaata agttctgcca atttgcatga
    27241 ttaagtataa cttgggtata aattttttgt gcatttgaaa gagcttattc tttttttgac
    27301 atattctttt aaataattta ccaccatttg gtaattggtc atcatcattc aaatttttaa
    27361 cttaatatga tttaaataaa tttataataa tgatataata taaaaaaaat aaaaattgga
    27421 gagtgatttc aaaatgaagt ttaatttttg ccataacaat ttcaatgtta ctaacttaga
    27481 aaaaagttta gatttttata aaaaagcttt agggcttaaa gaggtaaagc gtaaggaagc
    27541 agaagatgga agttttatat tagtttattt aggagatggt attactagtc atacactaga
    27601 attaacttgg cttagagatt gggatagacc atataattta ggagacaatg aatttcatct
    27661 ggctttagaa gttgaggagt ttgatgaggc aaaaaaactt cataaagatt tagattgcat
    27721 atgttttgaa aatgaaagta tgggaattta ttttatagcg gacccagata attattggat
    27781 tgaaatactt cctaaaaatc attaatttta aggatatgtt tataatttct ttacaattaa
    27841 taagagaata agttatcatt aaattgtagg gactaaaaat ggataataat gttatgaatt
    27901 tatgactata aaaatttgtt ggggggagtg atagtagtga agaaagctat agcagcttta
    27961 ggaattgggg cagtagcagt atctgttagc tccataaatg caagtgctct tgaaaaggga
    28021 acagtaacag caagtgcctt gaatataaga agtggaccaa gttctgattg tgataaggta
    28081 gcaaaattat acaagggaaa aactgtagag attttagaaa agtctaatgg atggtataaa
    28141 gtaagggtat cgagttctgt tgttggatgg ggaagcgcaa aatacatatc aacaagtggt
    28201 tcatctgaag gtacatcaaa tcaaaataat ccaacttcaa gtgggacaac tattagtgga
    28261 aatggtaaag taaatgtgag ttctagactg aatgtaagaa gtggtgcagg tactaactat
    28321 tcattagttg gtaaagcaaa taatggagat gtagtaaagt tactagaaca aagcaatgga
    28381 tggtataaaa taaaactatc aaatggagtt actggatggg ctagtagcca atatatctct
    28441 aaaacatcag aggatgttgg aacgaataat tctagtaatt caaatagtac taataattct
    28501 gataaaaaac catctagcga agaatcaatt gaaggcaaga atggtaaggt aacatctgct
    28561 gtgagtttaa atgtaagaag tggtcctggg acaagctatt ctataatagg aaaattaaat
    28621 ggtggagatg ttgttgaatt aaaagctaaa agtaatggtt ggtataaggt aaagttatcg
    28681 agtggaacaa ttggatgggt gagtgccagt tatatttctg agactaatga ggatacaaaa
    28741 gaaaaaccaa attcatcatc taaccaaaat tctcaatcta atagtaactc aaagccatca
    28801 tttactggaa attcagataa atctacagca aaaggttcaa caatcgtaga ttttgcatat
    28861 actcttattg gaataccata tcaatgggga gcttcaggac ctgataaatt tgactgttct
    28921 ggatttacac agtatgtttt taaacattct gtaggcgttt ctattcctag agtttctaga
    28981 gaacaggcta attttggaag tgcaatttct atgggaaatt atgcaccagg agatttagtt
    29041 tattttgaca ctgatggtga tggaacaact aatcatgtag gtatatatgt aggaaatagt
    29101 aaatttatcc attgtagtgg tactcagact aatcctaata aggttaaagt ggataattta
    29161 actagttcat attggtctaa agtattactt ggtgcaagaa gatttgttta gtaagtacaa
    29221 tttcttatta aaaaattaga agaaataatt atttatattc ataaattgtg actcttaaaa
    29281 atatacttta ttaataatat aattttggga gggacaaact aatgaataga agaaaaacga
    29341 tatacagagg atttaataat aatagacata agattgattt acgtaaatat gttataacga
    29401 ttgcttgctt gtgtctaatt ggctattatt cttatacaaa aataaaagat agcaagatat
    29461 tggagtatgt atcggctaaa ataccatttc taaataattc atcagatata acttataaag
    29521 atatatctga tgaattaaat tcaataaaaa aagggaaaaa atctaaatca caaaccaatt
    29581 cagatgataa acaagaaaat aatccagaaa aagcggtaaa taacactaaa gagccagaag
    29641 aagtcaagtt agctactata gaaggctggg atatgtatac tattcaagtt gctgcaatag
    29701 ataataatga tgatttgaaa aaaatacaga catcattagt taataatgac ataccttttt
    29761 cagttatgga gaaggatgga gtaaaaaaaa tacagaccta ttcctctttt gatgaaaatg
    29821 atgttagaaa gcagataagc agtgtaagaa aggtgtttcc agatgcattt ttatcacact
    29881 tagatgcacc tatgttgtct ttagagtata caagtaacta cgcttatata gagagtatat
    29941 ctaaagaatt aaataaatta ataacaaact ttaaagaaga atcaagtttt tggtcgaatg
    30001 ctgaaaataa tgtagatatg gaaaaatata atactatttt gacaaataga aaggcaatat
    30061 cacaaaatat atcaaaagaa gccgaaaaga ttgactattc tgaaatgcgt ttatttaaag
    30121 ataatttaat agagtatgta aagaatgtga atgaaaaaat tgatacagct tcaaaagcag
    30181 caaatgaaga aaaatatagt gtaagtaaaa gtctgctttt atcatccatg caggagtact
    30241 ctatgtttat aaattctata aaataaaata cagaaaattt ggactttaga aagctatatg
    30301 aaaaggattg tttaattaag caatcctttt cctcggtttg acttaatata gaggtattga
    30361 tttataaaat aaattataaa aatacggata tttttttaac aattgttaag attttttaat
    30421 atatatagta tacttataga aggcagaaaa aatgtttttt tatagataag ggggtaaaac
    30481 aatgaaactc ttaactttta agggagggat acatcctcca tatagaaaag agtactctaa
    30541 cacaaaggca cttgaaaaag ctcaagctcc aaagatagtt tacattcctc ttcagcaaca
    30601 tataggggca ccagctaaac ctattgttga agttggtgat gaagtaaagt ttgggcaaaa
    30661 aataggtgaa caacaaggtt ttgtttcatg taacgttcat tcttcagtat caggtaaagt
    30721 tattgctatt gaacaacatg aagtaccagg aggttcagct caatgtgtag ttatcgaaaa
    30781 tgactttaag gaagaattac atgagagtgt tcaaccaaaa ggtcagttag aggatttgag
    30841 caaagaagat atagtaggta tcataaaaga ggcaggaata gtaggtatgg gtggagctac
    30901 attccctaac catgtaaaag tatctcctcc accagatagc aaggcagaag tagttatatt
    30961 aaatggtgca gaatgtgaac catacttaac tgcagaccac agattaatgg ttgaaaatcc
    31021 agaagatgtt gtgtttggtt taagagcatt aatgaaggta ttagatgtca aaaaaggatt
    31081 tataggaatt gaaacgaata aaccagatgc tatagaagca attcaaaatg tagctaaaga
    31141 ctatagtgaa atcgaagttg ttggccttca agtgaaatat ccacaaggag cagagaaaca
    31201 acttatttat gcgtgtacag gcaaagaagt tccatctggt ggattaccaa tagcagcagg
    31261 tgcagttgtt gacaacgttg ccacagcagc acaaatagct aagtctatta aaacaggtat
    31321 gcctttggtt gaaagaatca ctacaataac aggtagttgc atcaaagagc caaagaacct
    31381 aataacaaaa gttggaacat tagtttcaga aataatagaa caatgtggtg gatttaaaga
    31441 agataagaag attggtaagg ttataatggg tggacctatg atgggaatag ctcaatatac
    31501 tactgaaata gcgactaaca aaggttcttc aggaatttta tgtttggatg aggaagaatc
    31561 acgtactcca gatattcaaa actgtttaag atgtggaaga tgtacagatg tatgtccatc
    31621 attcttacaa ccacttttca taagtgcata ttctttaaaa gatgactatg acacagctga
    31681 atatcataga gcaatggatt gtatagaatg tgggtcttgc tcatttattt gtccagcaag
    31741 aagaccatta cttcaatcta taagatcagc aaagagagaa ataggagcaa agagaagaaa
    31801 gcaagctgct cagaaataaa gaaagttaag ggggaaaaac gatggaaaat aagttgatag
    31861 tatcatcttc tcctcatgtg agaagtaatg aagatacttc atatataatg aaacaagtta
    31921 ttatagcact ccttccagca gcagtagcag gagtatactt ctttagactt aatgctttga
    31981 gtgctatgtt tttttgtata cttggtacag taggtactga atttttatat caaaaattta
    32041 cgaagcaaaa aagtactata ggagattttt cagctgttgt aacaggatta ttattagcat
    32101 ttaacgtacc agcatcactt ccttggtgga tgtgtctagt aggaggaata tttgcaatat
    32161 tagtagttaa aatggtattt ggtggaattg gatgtaactt tgtcaatcca gcacttgctg
    32221 caagagcatt tttattagca tcattcccag tagcaatgac tgcttggact caaccaggtg
    32281 ttaactggat aggtaaaaat ttagatgcag ttactacagc aactccatta agctttttga
    32341 aaaatggagc agcaggactg gcagaccttt ctagcaatgg aattagtctt gctgacatga
    32401 tgatagggaa tattggtgga tgtataggtg agacatcagc aatattatta ttattaggtg
    32461 gagtatacct aatgtataaa ggcataataa attatgttat accagtattt tacatagcaa
    32521 ctgtatttat attaacattc cttttaggtg gatttaatat aactttcgca atatatcaac
    32581 tgtttgctgg aggacttatg ttaggtggat tcttcatgct tacggattat acaacttcgc
    32641 ctatgactaa aaaaggtcaa ataatatacg ctgtattagc tggtcttata acaactgtta
    32701 taagaatgta tggtggatat ccagaaggtg tatcttactc aatactatta gtgaactgtc
    32761 ttgctccact tatagataag tttgttagaa atagagtatt tggggaggtg gctaaataat
    32821 gaacagtatg gtgagattag gtggtacttt acttgctata agtgcaatag ctgcattagc
    32881 tcttggagct actaatcagg ttacagctcc agtaatagaa caaagaaata tacaagcaaa
    32941 taatgaactt agaaaagcag tccttccaga agcaaaagaa tttaaagaaa tggataaaag
    33001 tacatataaa gaccttggag atggtcttat agctgaagtg tatgaaggtt tagatggttc
    33061 tgaagtggtt ggatatactt taaaagctaa accaagtgga tatggtggag aaattgaagt
    33121 tatggtaggt atatcatctg aaggtcaagt tacaggtgtt gacattggta atatgtcaga
    33181 aacagcaggt cttggagcaa aagctaagga tgatgcattt aagggtcaat ataaaggaaa
    33241 aactgctgag cctcttgaag tagcaaaagg aagtacaaca gcagataatc aaatattagc
    33301 aatatcaggt gcaactatta catctacagc agttactaca ggagtaaatg ctgctataga
    33361 tgttttcaat agtgctctta ataaataagg agggttaatt atgaatttag ctaaagtatt
    33421 taaaaatggg ctaatagatg agaacccaac atttgttcaa gttataggta tgtgtccaac
    33481 actagccgtt acaacttcag caataaatgg aattggtatg ggtctttcaa cagcagcagt
    33541 tttaatatgt gcaaatttag ttatatcttt aataagaaaa attacaccag ataagataag
    33601 aatacctata tttatagtag ttatagctac atttgttaca atagtaggta tgcttttaaa
    33661 agcatatgtt cctgctcttg ataaggctct tggtatatat ataccattaa tagttgttaa
    33721 ctgtttaata ttagctcgtg cagaaagttt tgctttcaaa acaggagcta tgccttcaat
    33781 agttgatggt gtaggtcaag gtcttggatt tactgttgca cttacaataa taggtgcagt
    33841 aagagaatta cttggaaatg gtagtttatt tggaatgaca ttatttggag catctttcca
    33901 accagtatta atatttatat taccaccagg tgcattctta acattaggat tcttatttgc
    33961 aggatttaat aaattaagaa gtaaaaaagc atagtggagg tgtaataaat gaatttaata
    34021 cttttatttt taagtatcgt tcttgttaat aacgttataa catctcaatt cttgggtata
    34081 tgtcctttct tgggagtttc taagaaggtt gatacagcag tagggatggg agttgcggtt
    34141 acgttcgttt taactctagc ttcaattata acttatttta tacagatttt attagtaaaa
    34201 actggaactg gattcttaca aacaatagct tttatattgg ttatagcttc tatagttcag
    34261 ttcgttgaaa tggtaattca aaagatgagt ccatctttat atcaagcatt aggagtttat
    34321 ttacctctta taactacaaa ctgtgcagtt cttggtatag ctctagttaa tgttcaaaaa
    34381 agttataatt tagtagaaac aataataaat ggatttggag ccggagctgg atttacttta
    34441 gcaatagtaa tattcgcagg tataagagaa agactagaat tagctgatat accagaagca
    34501 tttaaaggtt tccctataac gcttatatca gcaggtttaa tgtcaatagc tttcttagga
    34561 tttacaggac ttataaagct ataaaaaaga ggggtgaaaa tggtgatact tacagctgta
    34621 ttagttttag gaattatggg cttaatcttc gggatagtac tagatttcgc atctaaaaag
    34681 tttgctgtag aagtagacga gagagtggaa gctatactag gagtacttcc aggagccaac
    34741 tgtggaggtt gtggatttcc aggttgtgga ggtcttgcaa atgcgatagt tgaaggcaat
    34801 gcaccagtta atggttgccc tgtaggtgga gcagatgttg gtgcaaaagt tggagaaata
    34861 atgggaataa gtgctgaagc aggtgagaaa caagtagcaa aagttatttg taaaggaact
    34921 tgttcaagtg caaaagataa atatgagtat gaaggaatat cagattgtag agcagcaaat
    34981 gttttaaact caggtgctaa gatgtgtaaa tttggatgtt taggtcttgg aacatgtaaa
    35041 gatgcttgta aatttgatgc tatttctata gttgatggaa tagcagtaat agatgaagaa
    35101 aagtgtgtaa attgtggaaa atgtaaagaa gtttgtccta agggtataat aatcacaaaa
    35161 ccagaaagtc aagaagtagt tgtagagtgt aatagcaaag agtttggtaa agctgttaag
    35221 gaaaaatgta ctgctggatg tattggctgt ggaatgtgtg taaaagcttg taaatttgat
    35281 gcaataatat ttgaagacaa aatagctaag atagacccta ataagtgtgt agggtgtatg
    35341 caatgtgtag caaaatgccc tacaaaagta atatcaggtg acataactaa gaaaaagaaa
    35401 gttactattg accaagaact ttgtgttgga tgtacagtgt gcaaaaaaca atgtaagttt
    35461 gatgcaatag agggagaatt aaaagaaaaa cataaggtag atgcagataa atgtgtagga
    35521 tgccatttat gtatggaaaa atgtccaaag aaagctatta aaattttgta atatggacaa
    35581 aataaggata tggaataatt tccatatctc taatgagtac ataaaacaga ggtatggaat
    35641 aatttccata cctctatttt atgtatattt attctaatgg taataaatat aacaatagtg
    35701 taacaaaaaa ggttcgacat ttctgttgaa ttttttacaa tatagtgata gactaaatag
    35761 gtacaaatta cgtacaaatg aggtgaataa atgaatataa tcttggcatc agcctctcca
    35821 agaaggaaag aaattctaga gaatacgaat gtaagatttg atataattaa aaatgaaatt
    35881 gatgagatta tattggaagg tgaaacacca aaacatttag ttatgagatt agcttttgaa
    35941 aaaagtatgt ctgtagcatc tgaacataat gaagatgttg ttattggagc tgatacagtt
    36001 gttgttttag acaatgctat tttaggaaaa ccaaaagatg agtcttgtgc aagagatatg
    36061 ttaaaaagac tatctggaag agagcatcaa gtcataacag gtattagctt aataaacttg
    36121 tgcgaagata aaaaggtaat tgactatgta atcagcaatg tgaaatttaa aacgttatca
    36181 gagcaggata ttgaggatta tctgaaaact aatgagtcat ttgacaaagc aggagcctat
    36241 ggtatacagg gttatggagc tttgttagtt gaagaaatta gaggagatta ttttaatata
    36301 gttggtcttc caatttcaag gttaggcgac ctattaaaaa aatattttag tataaatctt
    36361 ttttatggag tgtgatttat ctgaaaaagt catttaattc aaccattaag gtaaaagaaa
    36421 tggcaccaga ggaaagaccc agagaaaaga tgcttgccaa aggcgtaaaa agcttatcaa
    36481 atgctgagtt gttggctata cttttaagaa ctggcaacaa gaataaaaat gctattgaat
    36541 tagccaacta tataataaat agagatattc agggtattag acatttagaa gatatgacaa
    36601 tagaggagct gtgtaatata gatggaattg ggttatcaaa atcaacccaa attaaagcag
    36661 ctttagaact aggctctaga gtagctagtt ttaaacctat aaagtataaa ataaggaatc
    36721 cttgggatat acagaggtat tatatggata gcctaaggta tttaaaaaaa gaggttttta
    36781 aagcggttct tttaaacaca aaaaatgaga taatatctga tgtagatgta tctataggga
    36841 ctttaagctc gtcattagtc catccaagag aggtttttaa agaagctata agaagaagtg
    36901 caagtaagat aatagtgatg cataatcacc cctcaggaag tgtagaacca tcaagagaag
    36961 ataaaaatat cacatcaaga cttattaaat gtggagaaat aattggaata gaaataatag
    37021 accatataat tattggagat ggattatact ttagctttaa agaaaatatg ataatttgac
    37081 tttatatgtg ataaaataat aggagaatgt tttaaacatg attcttaata gtaggaagga
    37141 gtaaaatcat ggctaaggaa aaaaagaaag aaaaaaaagg tttttttagt tttaataaga
    37201 tgacaaagga tatgggaata gatttaggga ctgcaaatac attagtttac ataaaaggac
    37261 aaggtattgt tgttagagaa ccatcagttg tcgcaataag agatgatagt aaagaggtat
    37321 tagcagtagg tgaagaagcc aaaaaaatga taggtagaac accaggaaat atagtagcta
    37381 taagacctat gaaagatgga gtaatagctg attttgacat aactcaatca atgattagct
    37441 attttataca aaaagcggct gataaaaaag gtgttgtaag tccaagaata gctatatgtg
    37501 ttccttttgg agttacagaa gtagaaaaga gagctataga agaggctgca agacaagctg
    37561 gagctaaaga tgcattcctt atagaagagc caatggcagc ggctataggg gctggattaa
    37621 aagttgaaga accagaaggt aatatggtag ttgatattgg tggaggtact tcagaaatag
    37681 ctgtaatatc cttaggagga atcgttactg ctaaatctat aagaataggt ggagacgaat
    37741 ttgacgagtc tatagtggct tatgtaaaaa aagaatataa tcttatgata ggtgaaagaa
    37801 ctgctgaaaa tgtaaaaatt aacataggtt ctacatttaa agatgatgaa gaaataaata
    37861 tgcaaataag aggtagagat ttaatctcag gattacctaa aacaatagaa atatgctcta
    37921 cagaagttag agaagcatta aaagaacctg taagttcaat agtagatgca ataaaatcta
    37981 cactagaaag aactccacca gaattagcct cagatataat ggaaaacgga ataatgctaa
    38041 caggaggagg cgctttgctt agaggtcttg ataagcttat tacacaggaa actggtatgt
    38101 ctgtacaaat agcagaaaca cctcttgatt gtgttgcact tggaacaggt aaatctgttg
    38161 aagaccaaga aatctttgaa aaagtattaa tgatgaatac taagaattag aagttggtga
    38221 tggccttgag atttgacaag aacaaaaatg agaaaaaaaa gattaatgtt aaagtgatag
    38281 caacgggcgt agttgctatc actttaattg gaattgtggg tatatcaatt ggtaaatttt
    38341 ctagtggtag tccagtaaat ttgggagtag cttcagatgc tattacaagt gtaggtaagg
    38401 gaataaatga tggattttct tttatcaaaa atggttttaa agatgtagca aattttaaag
    38461 ataattctaa aaaggtaaaa aaattagaag aagaaaatga aaaacttaaa aaagatatga
    38521 tagctttaaa tgccaaacta gataaaacag aatcgctaga agagttaaaa aagacactga
    38581 actttgtaca agaagagtat aaggcgacaa gtatttcagc aagtgttgtt ggtaaaaatg
    38641 atggaaactg gtatgagagt tttgtcatag gtgcaggaaa aaattcaggt gtaaaaaaag
    38701 aaagtatagt tatgaatggt agtgggttag ttggcatagt ttatgaagtt tccaacaatt
    38761 atagtaaggc aatttcacta ttggattcta aggcatctgt aagctttaaa ctagcaaagg
    38821 atgccaatgc taaaggtaca attactcaaa atactacttt agataataaa gatagttata
    38881 atagtaaagg atatttgcaa ggatatatgt ttgactcatc atataatgta attcaaggag
    38941 atataataac aacatcaggt cttggattct tcccagatgg tataccaatt ggcgaagttg
    39001 aaaaggtggt tgatgataaa gataagtcat taaaatatgt agttgtaaaa ccttatgttg
    39061 attttaagaa tataaatgac gttgtagtca tagaaccaag aaatatagga taaaggggat
    39121 aaaaacaatg aaaaaagttt tactttgtct gttggggatt gtgcttatga ctatagaaaa
    39181 tagtataaca aattatatag atatttttgg cataagcttt aatttagttc ttatatatgt
    39241 aaccataatc tctctttatt tagatgaatt agaaggtggg attatagcag caataatagg
    39301 gcttattaaa gacataaccg ttggtggaat ttttggtgta aatgcattaa ttttgtttat
    39361 tattgcatat gcaattggat acatgagaga tcagctatat aaaggtagtt atattattac
    39421 tttcgtttta atttttatag gcagtttaat tgattcaatt gtcaatatag gtacatctag
    39481 tataatttat caaagctaca acatatcaac actttttgta aaaggtctac tagtagcacc
    39541 aatagtgaat agtttaattg gtttagtaat atatcgctta tctaaaagag cagttttaaa
    39601 acttaaagaa gattagttgg tgatttcatg gaagaaaata aacaagttga tagactaaaa
    39661 ataattaaga tagtcatggg cgtgatattt ttagctattt tagtaaaaat aatctatatg
    39721 actacattta aatatgaata ttacaatgag ttagctgaga ataaaacata taaaaagttg
    39781 gcaatagaag ctccaagagg agaaataaaa gatagatatg gaagactgtt ggcaggaaat
    39841 aaaaacttat ttactgttca agtttcaggt aacgatatta ataagaaaga tgcaaataag
    39901 cattcaagag caaatgaaat atcattaaaa cttataaatt tgctggagag aaatggtgaa
    39961 gaatatgtag atgagtttcc tatatatgta gaaaatggaa agtactatta tacatatgac
    40021 agagatatta gggaatataa atcagaaaat ggtattccaa atgattataa tgctaaggaa
    40081 agtttttatt acttagtaga caaacttata tcagctggaa tattatctca agaagataaa
    40141 agattggatg cgacaagatt acaggcaaaa ctaaatgaaa atggatatta tccacctatt
    40201 ttagttagta aatggatgtt cacagcagaa agagataaga gagattggtt ggctagttat
    40261 aagataaaag aaactaaact gagtgccaaa gaagcgtttg aaaaagtaag aaatagtgat
    40321 gcattagaaa ttgataaaag tttgagtgat gaagatgcaa gaaaaataat ggtcgtaagg
    40381 gatttgataa aatcaaaagg atattctcaa tataatccag taactattgc taaggatgta
    40441 ggagaaacta cgattgctca aattgaagaa agtgctatgg accttgttgg tgtttcaata
    40501 gcagtagaac cagtaagata ttatcctaat gggtcattag cttctcatat gttaggatat
    40561 gtaggaaaaa tgccatccac tcaaatagaa tcataccttc aaaaaggtta tgaaactgga
    40621 gatatggtag gtcttgcagg agtagaaaag agtaatgaaa gtagattaag aggaactgat
    40681 ggttataaaa tggttaaagt tgatgcattg ggtagaatca gtaaagaaat tgaatctaaa
    40741 aaacctaaat caggagatac tgtgtatctt acactagata aagatttaca agaagtttca
    40801 gataatgcat taaaacagat aatcgaagtt gcttctaaag gaggtacttt taaaagtaaa
    40861 tttggggaca aaccaattag tgcatatgca ggaaaagcac agtcagcagc tcttatagct
    40921 attgatgtta aaaatggaga agtattagct tcatcaagtt atcctaatta tgacccaaat
    40981 aaatttgcaa aaggtatttc tacagaggat tataaagcac ttcaaccaaa aaatccaaat
    41041 gacttactag caggaagtcc acttttaaac ttggttacac aaggggaatt tcagccaggt
    41101 tcttcattta agatggtaac ttcaatggca gcattagaaa atggtttgga tccaaacttt
    41161 actataaatg accctggggt tataatgtta ggtaaaaaat cttttggtga ctatgtatgg
    41221 aaccatggta gaggaaacca tggtatgaca aacttatata aagcgataca agagtcttgt
    41281 aatatatata tggcaacaat tggtacaggt aaaacatggc cagatggaaa aagcattggt
    41341 atagatatga atgcaaataa aatacttgag tatgcaaaat tatttgggct tgaccaaaat
    41401 acagggcttc aagatgaagt agaagaaaga gcaggtaaag ttcctagcac agaagataaa
    41461 ttgaaatcaa cacaagctct tctaaagtca aatttagaaa gagaaatggc aaatgatttt
    41521 gttgatataa ctagagaaaa aaatcctaaa gaatatgaga aaagaatcaa tgagattgta
    41581 agctgggcag cagaaaagaa aactcctggt agagtcgaaa caatgaatag gctaaagaaa
    41641 atgaatgtta aagaagatag aatagaagaa gtagcagatt tagcagtatt cagttatttt
    41701 aactttgcaa aatggagtac tgcagataca tttaacttag ctataggtca aggtgaaaat
    41761 gcttatacac cagctcaaat atcaagatat gtagctgcta tagcaaatgg aggtaattta
    41821 gtagaattat ctgtagttga tagagctgtt tcaagtgatt attcatcagt taaaattaat
    41881 gaccagaaga aagtcgaaaa aatacctttt aaaaatccag ataacttaaa agaattaaca
    41941 aaaggtatga aattggttgc aagacaaggt acagcgaaga gtgcttttgc tgattttcca
    42001 atagatgtag cagcaaaaac tggtacagct gagaaaagtg ggaaaatacc tacagataac
    42061 gagtatgaat atttaaaaag tcatatgtca tcttataatg tcaacctaaa tgatgcgatt
    42121 aaactagctg ataagatgaa agcagaaaaa gaaaaagagc tttcattagc taaggaaaag
    42181 gaaataaaaa agaaattaga aaataaagat ttgaaagacg aagaaagaaa gaaattagag
    42241 gaagaattag aagatggagt aaaagttaga ttagaggaca ctgataaggt gaattcttca
    42301 tatctaagaa aagctataaa agaattaaat ccaaaaataa cagatgacca aatagataga
    42361 tttaaacaag attatggttc ttttacatgg actgttgctt ttgctccagc agatgaccca
    42421 gaaatagctg ttgtatgtgt aattcctcaa ggtgattcaa gtgtattctc acttttacca
    42481 actagagaag ttattggaac ttatatggga ttagagccaa ctaatagtaa aaatgacaac
    42541 aagacgaatg atgttaacaa ttcttctgac gaaaatataa atttcgagtc acaaattaat
    42601 agatagctca atctatgtat aaactttagc tttatataga aaaaataaaa gggtttaaag
    42661 cgtatttgaa gaatataaat gatatatcac tctggaggtt gttatgtctt taagagaaat
    42721 ttgtagtcaa gaactagtag agttcaaggg taataaaaga gggataatag taaatataaa
    42781 aagagaagct ccatttgagg aaatacagga aaaaataata aacaaattgg aagcatatgt
    42841 tggctttttt aatggggcta aaattagtaa aattaatagt gattgtttaa ctgacatgga
    42901 gattctagaa cttaaagaag gaattacttc tagatttgat gtggaatttg ttgaagatca
    42961 aaaaattgaa gaaaatagta attttccaac aaaatatgtc aataccctaa gatctggtga
    43021 aaatattgaa tttgaaggtg atgtagttat attgaatgat atgaaacctg gttcaaaagt
    43081 cctttcaaaa tcaaatacag ttgttatggg agatataaat gctggtgcta aggttgtagc
    43141 aggaggtaat gtttttgtaa tgggtaaaat agaaggcttt gtacatgcag gtgcagaagg
    43201 caatgaattt gcatatgttg ttgctggaaa tcttaatcct aaaatattac aaatagcaga
    43261 taatattgca gaagctccag atgatgaaga aaattatgaa agtgaatcag aaattagccc
    43321 agaaatagcc tttgtaagta atggaagaat tgtaatcgaa agctatttgt caaagttaga
    43381 caaatagaaa gaaaaatagg gggtagtatt atgagcgaag ttatagttat aacatctggt
    43441 aaaggtgggg ttggaaaaac tactaccgca gcaaacttag gaactgcgct aagcctagaa
    43501 aataaaaaaa cagtagttgt ggatgcagat attggactta gaaacttaga tgtagtaatg
    43561 ggtcttgaaa atcgaatagt ttatgacata gtagatgtag ttgaaggaac ttgtaggctt
    43621 aagcaagctc taataaaaga caaaagattt gataatctat atttattacc agcagcacaa
    43681 actagagata aaaatgctgt ctcagttgag cagatgattg acctgtgtga gaaactaaaa
    43741 gaatctttcg agtatataat aatagattgt ccagcaggta ttgagcaagg ctttaaaaat
    43801 gcagtagctg gggcagatag agctattgta gttactaatc cagaaatatc agcagtaaga
    43861 gatgctgata gaataatagg tctattagaa gcaaatgaaa taaaagagat aagattagtt
    43921 ataaatagaa ttagaaatga tatggttaag cgtggagaca tgatggataa acaagatata
    43981 atagaaatat tagcaataga tttgttaggt cttgttcctg atgatgaaag cataattata
    44041 tcaacaaata aaggagagcc agctatactt gattctaagt cacttgctgg tcaagcatac
    44101 aaaaatatcg caaaaaggat actaaatgaa gaagttcctc tacttgatct tgaagttgaa
    44161 gatggattct ttggtagact taaaaaaatg tttagcatgg ctaagtagca aaggaggata
    44221 catctgtgtt agatttattt agagtttttt ctaacgaggc taaaactagt aaatctgttg
    44281 ctaaagagag gttaaagcta gttttagttc atgatagagt agattgttca ccacaacttt
    44341 tagagatgat aaaaacagac attttaaaag taatagctaa ttatgcagaa atagaagatg
    44401 atggtcttga aataaaaatg tctaaatgca gaggtgagca tgatgacaaa cctgtatctg
    44461 cattagttgc taatatacca ctaaagaata taaaagatag atgtatgtaa ttagtgctta
    44521 aaagggggat atccttattg gtatatgccc cttttattta attatatgtt taaagataga
    44581 aagacggtga ttctttgaaa aaaatcaata ttaattataa gtcgacaatt aagttgataa
    44641 aacagttaga ctggaaactt atagttacag tattagctat ctttattttt gggcttgtta
    44701 tacttagtag tgcaacacat gctaattcaa caggttcata taatcaattg attaaacaag
    44761 gattagcttt tgtacttggt ataggaatga ttatagtcat attatttttt gactataacc
    44821 ttctaggcag gtattataaa gcgctttata taataagtct tattttgtta gccatagttt
    44881 tattacctgg aattgggaca gtaaaaggtg gagctaggtc gtggattaac ttaggaccac
    44941 ttgacttgca gacatctgaa atagtcaaat taacatttgt actaagttat gcaaagatac
    45001 ttgaatccaa aaaggataaa ttaaatacgt taaaggaagt tatgcctgtt gtagtttatt
    45061 ctcttccatt tatcggatta ttgattgcac aaccagactt gggaacagga attgtatttt
    45121 gttgtatgat atttgcaatg ctgttcacag caggtcttag ctcaaagttg ataaaaagag
    45181 gaataatcat actattagtg tcaatgccac tgatgtattt aatgatggca gaccatcaaa
    45241 aggtaagaat agaagctttt ctaaatccag aagatgtaac tctaaaagga aactatcaag
    45301 ttatgcaatc tctgattgca attggttctg gaggcgtaac tggtaaagga ctttacaatg
    45361 gaagtcaaaa tcaagaagat tttttacctg tacaagatag tgattttata tttgctgttg
    45421 taggtgaaga acttggtgta ataggaatgg cagtgttgat aatcttattt atgatattcc
    45481 tattaaggct tttagcaatt gcaagagatg caaaagattt ttatggaacc ctcatagtgg
    45541 ttggtgttat gggaatgttt ggttaccaga taatccaaaa tataggtatg acggttgcgt
    45601 taataccagt aactggagta acattacctt ttgtaagtta tggaggaagt tcgttattga
    45661 catctttagc aaacttagga ttagtactaa atgtgtgtat gagaagaaag aaaataaatt
    45721 tctaaattta aatacatcta aacataaatt gaggagatta gatatatgaa tatagcatta
    45781 gtagcacatg accaaatgaa aaacactatg gtcggatttt gtataggtta tgaatcaatt
    45841 ttaaaaaagt atggattata tgcaactgga actacaggaa aaagaataat ggatgaaact
    45901 gaattaaata taaatagatt agcatctggt cctttaggtg gagaccaaca aataggttct
    45961 ttaatagtaa cacaagaaat agatttagtt atttttttaa gagacccatt gacatctcag
    46021 gctcatgaaa cagatataca agcgttaata agactttgtg atgtttatca tgttccaata
    46081 gctacaaatc tagcttcagc agaaatattt ataaaagctc ttgatagagg agaactatca
    46141 tggagagagg tcagaaaaag caaaagtcaa cgtatttaaa aaatattaat attacagtct
    46201 aaagaaacag atatataagt gtttaatgcc ctagtttttc tgttgcaata aacctagtac
    46261 ctgtagaaat cttatgaaag atttaaatga tgaggagcta aatttgagat taaataatta
    46321 ggaaatagat tatagataga gtagtagaat ttaactatta ctctatttta ataatatgaa
    46381 atagaatcaa gtctattatt atatatattt aaacttatag gtaatactat ttcaatcaag
    46441 taaatattgt tacgacaaca ttaataaaac aaaaatttat ttttaaaatt taataaatag
    46501 ctgtatatta gtatttatag attaaatatt aatatacagc tatttattat ttttgagtct
    46561 attgtagaat ataaaccttg cattatagag tactatgtaa tattatagta aatataagta
    46621 ctatacatta tagagtagta ggtgaaaagg cggtggtaca taatgcagtt aaataaagaa
    46681 gtgttaaaag gttatatcga tatattaatt gtttctatat tagaaaagaa agattgttat
    46741 ggatatgaaa ttgcaaagca agtaagagaa agaagtgagt ttgaattaaa agaaggaaca
    46801 atgtatcttg cacttaaaag aatggaatct aaaaatttaa ttaaatctta ttatagcaat
    46861 gaacaaagtt caggtggaag aagaaaatat tataatttaa ctaatgaagg taaagatttt
    46921 ttagaaataa agaaacaaga atggagattt attaaaaagg ttatgaatca atttttggga
    46981 gaggtggatt aatttatgaa actaatagat gaatatttag ataaactata taaaaaatgt
    47041 gacaataaaa gtactataga attaaaacag gaaatgagat gccatcttat agaatctgca
    47101 aatgaattta aattagaagg attagatgaa gaagaagcat gtaaaaaagc aattgaaaga
    47161 tttgatgatg gtgatgaaat gcagtatgaa ttatgtaata taataaaaga actatcttta
    47221 tcattggata ggcataaatc aattgtaatg gggtttaaaa aagtattagg ttacataagt
    47281 ataattgcat ttttaatttc tggatttatg tggtattaca ataatagttt acaacataat
    47341 atgtataatt taggaaaaga acttgatgga gaaataaagc aattgacaga aagacatgat
    47401 atgacaaaga ttggtgaata taagttagaa cttgaaaaaa tacttgataa agataagtat
    47461 agtaaagtca aagctcttag actatatgta atagatatga aagatggaaa cactaattta
    47521 agttcttctg gattgaattc taatatggta tatgagaggg aagcagatta taataacata
    47581 agtaatttta tacagcattt aggatataat ggaaaagatt ttttagacaa gaatgggaat
    47641 atagtaaatc cagatatttt cttagaatat ttcttttatt ttgaatcgga gatgttaatt
    47701 ccagtagcat ttgcatttgg attattatgt ataatagcgt attttatatt aagatttaaa
    47761 atttctttaa taaaaaataa taattaaata attcaccaaa taatcttaat ttgtagagta
    47821 aataagatgt ttcaaaataa aatttgaatc atcttatttt ttattgtttg ttatactctt
    47881 ttcttttata tttctccata gtggattgta tctatacata atcacatatt ttgatataat
    47941 tatactttcc ccaaaatgta ttgaatatac aaattataat ctgtataatg ttgttggggg
    48001 agaatgtatg aagtgtatac aactttaatt ttaaatgtat tattgacaat tctcctcact
    48061 ctcgtcatta ctaataattg taaaattgac acacctgtta cagaccaaca tttttgaata
    48121 tagtaattag tatcatttta ttgtgatgat atcaaaaatg cagatttgtg agttggattg
    48181 tatacgaact atataagaaa tatagaacaa attttccaag aaatctaaat attctatgac
    48241 cacgtgaatt gctatgcaca catgttgata atccatattt taaatctaaa atgaacttaa
    48301 ttaatggtag ggaattgaaa gtaaaaatat attataaagg agaatgctaa tatgaaaaaa
    48361 atcaggaaat tatctactaa actattgatt gcaacgatgg ttttaacctc atgtatgaat
    48421 gtaacagttt atggtatgac agctaaagac gttactgcaa agacaccgaa aagctatgta
    48481 gctggaacca acagtatata tggtccaaag ttatcacaag ctcaacttaa ttcggtagca
    48541 caagcaacag cagactttat gaacaagaaa attacaaaga acatgaccac agatgctaag
    48601 attagggttg cttataatca cattaaaaac aacacaacat atgttaactg gaacgcagca
    48661 gagggagcca atactgctta tacattggtt actaaaaaag gtgtttgttc tggaatgtgt
    48721 aggagcttga aagctttatg tgatgctatg ggaattgaat gttattatgt acatagtaca
    48781 acaaatgacc atcagtggaa tcttattcgt tttgaggatg gacgtttgta tcatgtagat
    48841 attgatgcca acaaatcagc aggagcagac atcatataca agagtcttac tcacccatta
    48901 ccatttgaca agaaagccta tccagctgtt ggtgaagtag taaagacgca gaatccaacg
    48961 ccaactgtta agaaacctac accagctaag ccttctgcgc cagttggacc tgggaatcac
    49021 actatgatag cagatcaaga aggggcaata cttgatgaag tttatggaaa taatctacgt
    49081 cccaaaattg aaaggtatga gggagttcag tgtagtttaa tcaactcatc aataaataca
    49141 attaagttta caagcaaaaa ttcaaattta gacccatcaa ggcatacagt ttctgtaata
    49201 gggtttatga atacaccata tggtatggtt gcattagctc cagatggtgt acctgttgag
    49261 tatccttttg aatatgataa gccattttct ttagatttta ctggtaagaa cctttctgca
    49321 gcagaattat caaaaaagtg taaagaaaat aatgtaatta ttaaagtaga aattggtgaa
    49381 acaacatcta attctggaat agggctagta gcatatgcta gatacatgaa ttaatacaag
    49441 tatacaaata gaactgatta taaataatgc accctcttgg tgagggtgca tttatcatta
    49501 tattagtcat tttggaaaat aaaaaaggag ttgaacttaa aattagatta gaaaaattaa
    49561 ttttgagaca actccatttt aatttatttt taaatataaa atcatttatt ttaaataata
    49621 ttatgtgtga ttaatggcta tttaactaat tttgcaaatt ctgcaccaaa tgccatacac
    49681 tcttttaatg tctcttcact agggaagaat tttttcttaa gagattctac aggcattttg
    49741 aatgacatag atttaagtaa agtctcagcc atagttatac cttcaccact ccaaccaaat
    49801 gaaccaaata ctcctgctat cttgccttgg ttagccattg ggtctataac agagaataaa
    49861 tcccacatag gtttaaccat agttttgttt atagttggag aacctagtaa tattactttt
    49921 gacactacta atgtatcgtg catttctgtt aatgtcatat cttctaaatc atataattca
    49981 gcctttgcac cttctttatc aagtccttct tttatctttt tagccatctc taaagtatta
    50041 ctataagctg ataagtagaa tatagaaact tgattttgat tagttgtatt aacagcttct
    50101 gtagaccact caacatatct tttaacagca gccattgggt ctttagtaag cattggacca
    50161 tgagaagtca atatagtatc aaattctatg tttagtccta ccaccttatc tacagcactt
    50221 aaaacatgtt tagcaaatgg cttaactata caatcatagt agtgtttagc tgattttaga
    50281 taatcttcac tattcactac ctctgcatca acacttgcaa agtgacaacc aaatgcatca
    50341 caagttaaaa gagtcttgtc ctcctcaatg taagtaaaca ttgtatcaac ccaatgtaag
    50401 aatggagcag ttataaatct aagatttctt ttaccgatat ttaaaatttc accatctttt
    50461 attacatgac agttaaaagg tctatttatt tgaccatcta agtatagttt agcagcttta
    50521 gtacaataaa cttctatatt aggatttata tctaataagt attttaaact acctgcatgg
    50581 tctggttctg tgtgatgaat tacaacatag tcaattttag ctatatcagt aacctctgat
    50641 aaattactta aaaactcatc tttaaaattt gcctttacag tgtcaaataa aaccgttttt
    50701 tcgtccttga ttaaataaga gttgtaagtt gtcccaaact cagtttccat tattatgtcg
    50761 aatactttta aaccttcatc tactacgcca gtaaagtaga tatctttttt tacttcaaaa
    50821 actttactca tttttaaccc tcctaaaatt tatcattata taagtaacat acccaatttt
    50881 gaggtgaatg aaacaaaaga tgtcatgata agtcatgtaa aacaatagtt ttatgtttat
    50941 aatatatcat actttgtaaa aaaattgtat ttcaataaaa atttaataga aaatattctt
    51001 aaatattttt agctattcta ttttgtgaat aatatgtatt ttaaattcaa tattttagtt
    51061 atatttttga tagaaaatat tttatcgtgt ataatattac ttataaataa gaataaaaat
    51121 aaagagcttg tttggaggaa ttttaataaa tgaataaagt agacttgaaa aaaatcttaa
    51181 aaaaagtaga aaagcctgct agatatcttg gaaatgaaat aaattcaatt cataaagata
    51241 ctagtaatag tgaattgata agatatgcac attgctttcc agatttatat gaagttggta
    51301 tgagtcactt agggagtcat atattatatg atgtaataaa taaggatgaa gatgtatttt
    51361 gtgagagagt gtattctcct gcagttgata tggaaaatat aatgagagaa aaaagtatac
    51421 cattatttgc attagagtca agagagccta taacaaactt tgattttgtc acttttacac
    51481 ttcaatatga actttcatac actaatatct taaatatatt agatttagcc aatataccaa
    51541 tattaaaaga agaaagaact ttggaagacc catttataat ggttggtggt ccttgtgctt
    51601 ataattccga accattagca gattttgtag atgtagtaat attaggtgaa ggtgaagagg
    51661 ttaatttaga agtagtaaat gagtataaag aatggaagaa aaataaaacg actagagaag
    51721 attttttata taaaatatct agcatagaag gagtatacat accaagtttt tatgatgtca
    51781 agtacaatga agatggtaca gttcaaagtg taactcctaa tagagaaggg attactaaaa
    51841 atcctactaa aaggataata aaagatgttg agactgtaga ttatccagaa aaactaatag
    51901 taccttatat agatactgtt catgatagaa tagtactaga attatttaga ggatgtacta
    51961 gaggatgtag attctgtcaa gcaggtatga tatacaggcc aataagagaa aagagtgtta
    52021 aaagacttaa agaaatatta gataaattag ttaagaatac tggatatgat gaaatatcat
    52081 tatcatcact tagtacgagt gattatagta agttatcaga gttgactgat tatttggtag
    52141 atgaatatgc atctaataat attgggattt cgcttccatc ccttagatta gataattttt
    52201 caatggaaat tgctgataaa atacaacaag taagaaaatc tggacttact tttgctccag
    52261 aagcaggaac tcaaagactt agagatgtta taaataaagg tgttacagaa gaagatttgg
    52321 aaaatgcaac agaaagagct tttgagatgg ggtggaatag tgttaagttg tattttatga
    52381 ttggtttacc aactgagact tatgaagatt tagatggtat agctaaatta gcttataaag
    52441 ttattgatat ttatagaaaa gtaaatggag gaaaactaaa gagaagtttt agtgttacag
    52501 tgagtacttc tacatttgta ccaaagccat ttacaccttt ccaatggcat ggtcaagata
    52561 ctacagaaga agttattaat aagcagagac atttagtaaa taaattaaga aataacaata
    52621 taaaatacaa ttatcatgat tcaaagacta gtttgatgga agcagtagta gctagaggcg
    52681 atagaagaat aggaaaagtt atatatgatg catttagact aggtgctaaa tttgatggat
    52741 gggcagaaca ttttaattta gatatatgga aagaagctat ggaaaagaat aatctttcta
    52801 tagattttta tgcacataga aatagaaact atgaagaggt atttccttgg gaccatatag
    52861 atgtaggtat tagtaaaaaa ttcttaatta gagaagacga aaatgctaaa aaagaaaaaa
    52921 tcacttctga ttgtagacat aactgcaatg gttgtggaat aaatatacat gatataggaa
    52981 gggggctttg ctaatatgag taagataata agagtaaaat ttaaaaagga aggcgacatg
    53041 atatatatat cacatcttga ccttcagaga ttgttacaaa gagcgtttag aagagctgaa
    53101 ataaacttat cacattctca aggatttaat cctcacccta aaatgagtta tggcaatgct
    53161 ttggctttag ggacagaaag tcaaggtgag tatgtagata ttgaaataga agaagatgat
    53221 ttatcagtag aggaattttt aaataaagta tcaattcaac ttccagatgg gatagatttt
    53281 atcaaagcaa aagaaattga tagacaaaca ccttctcttt cttctgtgat agactatgga
    53341 gaatatttgt ttaatataga tttgaaaaga cctatgacga aagagtttgt aaaaagaaaa
    53401 gtaattgact ttatgaataa taaagaaata atcataacaa aaaagaataa aaaaggtaag
    53461 atggttgaag tagatataag acctatgata agaacctttg atgttttaaa tttagaagat
    53521 gaacatatta ctcttactgc tactatagct acaggctcaa aaactaattt aaatactaat
    53581 atacttatac caaagatatt agagatgttt gaacttgata ttgacccatt agatgttgat
    53641 atattgagaa gagatttata tgtattagaa gatggggaat tagtgactcc tatgtaagct
    53701 cgagaggtga agttgtgaaa aagatagtta ttgagtccct aatagggtcc cagaaaacag
    53761 cagtacttga agatgaaaga ttaacagaac tttttgttga agacaattta aataagaaga
    53821 ctgtatccaa tatatatcgt ggaatcgtaa aaaaagttat accaggaata gaagcttgtt
    53881 ttgtagatat tggatttaag aaacttgctt atttacaatt aaaaaaggga agtactataa
    53941 aatctggtca ggatattttg gttcagataa ataaagaaga aataggaact aaaggcgcaa
    54001 aattaaacac tgagattagt atttctggaa ggtatattgt ctatatacct tccaatgata
    54061 gaactacaat atcaaataaa attactgatg aaaaagaacg atttagatta aaaaaaatta
    54121 ctaaggcagt aaataaggaa aatctaggat taataataag gactgaggct caaggttgca
    54181 ctcatgatga aataaagaaa gatatagaag agttgaaatt aaagtatgaa aacattttaa
    54241 aagaatataa acttggtata ggtccgaaat tattatataa gtctttagat tttgcaacta
    54301 aatatgtaaa agataatgtg aatgatgata ttgaatctat aattaccaat agttatgata
    54361 agtactctga acttaagtct attttaagag gtatagataa gacttatgtt gataaactgt
    54421 gtcttgagga aaatagagat gtatttgatt tatacagaat agaatctaaa atagaaaaat
    54481 tattaaataa aaaagtatgg ttaaagagtg gaggttattt aataattgaa aaaacagaag
    54541 ctcttacggt tatagatgta aatacgggta agtttattgg aactggtaaa cttgatgaaa
    54601 ccgtttataa aactaatctt gaagctgcaa aagaaattgt aagacagctt agaattagag
    54661 acatagctgg gataataata atcgatttta ttgatatgca taaaaagaag catcaaaagg
    54721 agattttaca catcctagaa gaagaattta ataaagataa aagaaaagct gaagtattag
    54781 gtatgacaaa acttggttta gtagaagttg ctaggcgtag agaaaaagaa tccattgata
    54841 agtattattt aatgtcttgt ccatgttgtg atggtgaaca aacaataaaa tctgtacatt
    54901 atatactaga tagtattgaa aaagaaatta tgagaataag tgaacatact gtttacaaaa
    54961 acataatggt agaatttaat gattttattt ttgaacaaat aaaagaatat tatatggata
    55021 taattgataa aattggtgaa aaatataata taaagatttc tttaaacgca aatagtacat
    55081 taaagcacaa taaaaccaat gttattttcg ataaaatagt tgacaataaa atgtaaatat
    55141 tttataatta ataattgtaa tgccgcacag taaaggttta aatcttcaaa tgaagtacct
    55201 tgtactggcg agtttgaggc cgaggaggtg tatttaatgt acgctatagt aaagactggt
    55261 ggaaagcaat ataaagtttc tgaaggtgat gtattattcg ttgaaaaatt agaagctaac
    55321 gcaggtgatg ttgttacttt aaacgaagta ttagcttgct ctaaagatgg agaattaaaa
    55381 ttaggttctc cagtagtaga aggagcatct gttcaagcta aagttgttga acaaggtaaa
    55441 gctaagaaag ttatagtttt caagtataaa gcaaaaaaag attacagaag aaaacaagga
    55501 catcgtcaat catatactaa gatagttgta gaaaaaataa acgcttagtt attggttaag
    55561 ttatgataaa agttaaatat tattataatg atgatttctt gttgcaaggt ttttgtttaa
    55621 agggacatgc tgattttgct gaaataggct atgatatagt atgtgctgca gttacatcta
    55681 atgctattgc agttataaat tctttagaca aattacaaaa gattgaattt gaaaaagtag
    55741 taggagaaga aggtcatata gagtgtatag tcaaagatac gcatgtaaaa gacgcacaat
    55801 tattactaaa tcactttcaa ttagcggttg aagaaattaa acgggaatac ccaaaaaata
    55861 taaaaatttt aaaaaagtag ggggtgactc catatgttaa acatgaattt acaattatta
    55921 gcatctaaaa aaggggtagg ttcttctaaa aatggtagag attctatatc taaaagatta
    55981 ggtgttaaga gattcgatgg tcaattagta actgctggaa gtataatagt tagacaaaga
    56041 ggaactaaaa tacatccagg aactaatgtt ggaaaaggta gtgatgatac tttatttgca
    56101 ttagttgatg gtactgttaa attcgaaaga aaagacaaga agagaaaaaa agttagtata
    56161 tatccagtag caatagctga gtaatataca taaaaggagt gttgaggcac tcctttttct
    56221 tataatactg atgaatttat aatggtattt ttggtaatgc taattaaaag tttttaatta
    56281 agtaggtgaa gaatttgttt atagataagg caagaatatt tgttaaggct ggaaatggtg
    56341 gaaatggttc ggtagcattt agaagagaaa aatacgttcc agctggtggt ccagacggtg
    56401 gagatggtgg tcgtggagca agcatcatat ttgaagttga tttggggctt agaactctaa
    56461 tggactttaa gtaccagaaa aaatatcaag ctcaaaatgg tggcgacgga agcaaaggaa
    56521 aaagagctgg taaaaatgga gaaaatttag tattaaaagt accagcaggt acagtaataa
    56581 gagatgaggc tacaggtctt gtattagcag atttaaaaaa agaaggagat acagctatag
    56641 ttgcaaaagg tggtataggt ggtaaaggta accaacactt tgcaaatgca gtaagacaag
    56701 ctccagcttt tgcaaaatct ggtacagatg gagaagaaag atggataact cttgaactta
    56761 aaatgatagc agatgtcggt cttttaggat ttcccaatgt aggtaaatca acatttctat
    56821 cagttgtaac taaagctaaa cccaaaattg caaactatca ttttacaaca cttacaccaa
    56881 atctaggtgt tgttcaaact aagtttggag atagttttgt acttgcagat atacctggaa
    56941 ttatagaggg tgcttctgaa ggcataggat taggtcatga gttcttaaga catgttgaga
    57001 gaacaaaggt attgatacat attgtagata tatctggatt agagggaaga gaccctattg
    57061 aagattttga caagataaat gatgagctta aattgtacaa tgaaaagctt tcaaagaggc
    57121 cacaagttgt agttgcaaat aaatttgata tattagaaga tgagagtaag tttgagaagt
    57181 ttaagagtga attagaaggc agaggatata cagtatttaa aatgtcagca gcaactcgtc
    57241 aaggcataga tgaagtaata gcctatgttt ctaaaatgct aaaagaagta gaagatgtgg
    57301 agctagtttc agaagaagaa atgtatagac cagaacttga tattggtact gaagaagagt
    57361 taagtataga tattgaagat ggtgtgtatg tagttacagg taaagcactt agaagaataa
    57421 tgtattctgt aaattttgat gatatggaat cccttcaata tttccaaaaa gctatggaga
    57481 gtcaaggtgt ttttgatagg cttagagaaa tgggaataga agatggagat gtggttaaaa
    57541 tttatgaatt agaatttgag ttttacaatt aatttaaata tagattatag ataatttaag
    57601 tatagaatta tagaggtgag aatatgttaa aaggaaaaca aagggcgtat ttaagatctt
    57661 tagcaaatac tttaaagcct actacacaaa ttggtaaaga aggtgttaca gagagtttct
    57721 tagagcaatt agatggtatg ttaagaacta gagaattagt aaaagttact atattagaaa
    57781 atgcaggtct tgatactaaa gaaactgcta atgcagtatg tgaagcttta agagctgaat
    57841 ttgtgcaggc tattggtttt aaatttacta tttacaagag gaatattgaa gagcctaaaa
    57901 tactttttcc aggacatgaa caggcgaaag caaagactaa aaataataat gttacaaaaa
    57961 agggtaaacc aactaaaaga gctgttagat aatagtttat atccttttag ggaaataagt
    58021 taaaaaaata gtgacaattg gaagaaattg tattatacta ttaaacataa attttaatta
    58081 gcaatcttat caagagtggc agagggactg gccctgtgaa gcccggcaac cagtatattt
    58141 aattatacat tggtgctaaa tcctgcagca tttatgctga aagatgagta taaacccgtc
    58201 atatggcttg agtttatact caagcttttt ttattggtat atttatatat ataaataatt
    58261 taatataatc aaaatgatgg gggtatgtta cagtgaagat agcaatatta gggtatggaa
    58321 cagtaggaag tggattaatt gatttaatag aaaataatac ttcaaaaaga gatatagaag
    58381 ttgttggaat tttagttaaa aataaagaaa aacacaagta taagaagtat tttgataaga
    58441 taactactga tatagaagat atatttgaca aggatattga tatactagtt gaagtaattg
    58501 gaggattaaa tccagctttt gattatgtaa caagagcgtt aaataaaaaa atacatgtag
    58561 tgacagctaa taaagattta ctggctgaaa aaggtagtga ccttatagaa ttagctaact
    58621 taaataatgt tagcatcaag tttgaagcat ctgtggcagg tggtattcca gttttaaaac
    58681 cattgataga atcactggaa ggcaacaata taaagagcat aaacgctatt ttaaatggga
    58741 cttgtaattt tatattatca aagatgtatg atgaaaattt accgtatgat gtcgctttaa
    58801 aacaggcaca agagttggga tttgcagaag ttaatccaga tgcagatgtt ttaggatatg
    58861 atagtgctag aaagttatct atattgtcta ctttatctta tggaaaaata gtatattgga
    58921 aagatttatt attagaagga ataacttcaa tagatgaaaa agatatagaa tatgctaaaa
    58981 aattaaattg taagataaaa ttggttgcta gaagtaagta tgaatcagga gaagtaagtg
    59041 gatttgttag accagcatta gtggacaata ataatatgct ttcaaagata gataatgagt
    59101 tcaacgtagt tattttagta ggtgattcag taggtgaact ttcctttgta ggtaagggag
    59161 ctggaagagg tgcaacagga agtgctgttt atgcagatat tatagatata atagataata
    59221 gaagttcaaa tataaagtct ttttcaaaag gtaaattgga tttaagtgga cttatagaag
    59281 atgagtgtag tgcagtagtt agatttggtg ggtataataa taaagatgga attttagaat
    59341 gtttagataa atatgtagat agttatgata ttatagatga tgaagaattg gcgatttttg
    59401 taagtgcaaa gtcagaacat gagattgata gagttttgga aattgtaaaa agaaataatt
    59461 acagtgaatc agctaaaaaa ttattgaaga tagattaata tgtttatgca agaattatga
    59521 aaatttaata gggtgtctca aaatagagag acaagccttt tttccagtat tgaaataata
    59581 aaaatatatt tgattttata aaaaaagagt gtctcatgaa ctaaaaagtt cattttgaga
    59641 cactcttttt taatatctgg tgaattaata agataataga aaaatgtata cgttataatt
    59701 aaccaataaa gaaattttca ctagcttcat taatagcttg ctgagttacc cttatatatc
    59761 gctgtgtagt ggctacagag ctgtgattta aaagttcttt aaccaactct aaattattgt
    59821 tactcttttc aaattgagta gtagcataga gctttctaaa gctatgtgta cttatattat
    59881 acagatttaa gtgtttacaa attatcctca actgtttttg aatagccttt gtctttatat
    59941 ttactaagta gtcatttgat ttaagattat actttcttgc atgttcattt atggactcaa
    60001 ttatattttt attaactggt ctatactgta atttgcccgt ctttttttca tttatttcca
    60061 acatattacc tttaaaatta cctatcttta atcttaaaat atctgatatt cttagaccta
    60121 aattagcttc taacattagt gccaatgcaa ctttaggatt ttttctaaat cttttttcaa
    60181 cgccattttc actataagta aagccagtat gtaatagttc cattatcttt ttatattcgt
    60241 ctatttctat aggtcttgtt gccattttca accactcctc ttagtttgat ttggtaagtt
    60301 taggtcggta tttattatat aatataaatg aaacattata taatggaaaa atttcccagt
    60361 aaacttatac aagtgtgata tatgtgatta aggagaattt tttgaaaaat atttctaata
    60421 aaattattaa attgtgatga aataactatg ctgttaaact aattaaaaag gttattaaaa
    60481 ttatgacaaa tataataaaa aaatggaagt atttagttaa gttttattag ttttattttt
    60541 ttcgtgaaaa tttcttaata aaaaaagtat ttttatatcg cattagtttc ccatttgtag
    60601 ataaagtttt catatgtttt tttgcaataa atactgctga gattagataa attattacta
    60661 caatttgaag aattgtatca taatagctaa gataataaaa ccagattaaa ttattatata
    60721 taacgttgta tgtatcagca aagctagaaa ccaacacagc agagtttgca attggataaa
    60781 gtataaatat aaagatagca gctaaaactc catgcgcaaa tttacttagt atgtataatt
    60841 ttaaatctat gtccgttttt gatagaaatg tacaacattg agctaggatg gataatccac
    60901 taaatcctat caaaaagcta gctaaagatg ctcttaaaat ttctggagaa cttgttatac
    60961 tagatacttt attgcatcct atagtaattt caaatagacc acttacaaat gcttgacaga
    61021 gttctttact aacacctaaa aatgaaagag gcaaatatat aactgatgct attaatgaga
    61081 ttacattaaa aagagatagt attttaaata ctactgaaaa aacaattaca aatccaccaa
    61141 ctgtaagtaa tgtatttact ccattaaata cagcatttcc aaataaaaca aaaaaaccat
    61201 tcccacttga atttctaatg ttgattacat tttttatatt tgtttttaaa tccaattttg
    61261 tctttggaag attttcatta ccataatttc taaagaaaag accaaccaat atagttccta
    61321 gataatggca gagaatcatt aaataaccta agtttgaatt ttggaacata cctgtaccaa
    61381 ccgaacctat tatgaataaa ggtcctgatg tagaacaaaa agacacaagt ctttgtgctt
    61441 catgcttaga aatttgccca ttactcctaa attcagaagc taaacttact cctactggat
    61501 aaccagatac tgtagatata gcaaaagcta aagcgctctt tcctgaaaca ttaaatacaa
    61561 atctagttat gggattgatg ataaacccta taatatccac tatttttaaa tcaacaatta
    61621 agtttgctcc aattataaat ggtagtagtg atggaactaa aacattagac catatagaga
    61681 agccttctct tgcagatttt atagcttcat ttgggtatag gataatccct aaaactagaa
    61741 ctccaactat aatagctgga gcaaaaaaag caataatttt attttttttc ataatatcac
    61801 ctgtaaattt gagttataag atattatatt aaaagtaata aaaatatatg aatgtaatgg
    61861 tttaagatat ataatagata tatattacaa caacgattat catattggag gaaaaaatgt
    61921 ttaatagtat agctagtaaa aaagtttatg aacaagtaat tgagcaaata caatataaaa
    61981 tactaaatgg agagttaaaa aagggggata aattactatc agaaagagaa ttgtctgaac
    62041 aaatgaatgt gagtagaact tccataaggg aagctattag ggtattagag actatgggag
    62101 tgatagaaag cagacagggt gaaggaaatt ttatatgtac aaatatagaa aaaactttaa
    62161 tagaaccttt atctatgatt tttaaactta ataatggtac acttgaagat atattagagc
    62221 ttagaataat cctagaaatt gagattgcaa aacttgcttc aaagagaata acttcttctg
    62281 aagttataga attgaaacat ataatagatg aaatgagagt agaaactaat aaaaaagata
    62341 ataatcgagt actggtgtta ttagaccaaa aatttcacag taaactagca acattaagta
    62401 aaaattattt aattcaaagt ctttttatga cagcatcaaa attatttgat ggatttatag
    62461 aagatgcaag agaaaaaata atcgcagaac cttttaatga aaatatattg cttaaacagc
    62521 atgaagctat atacaatgca gttatagaaa atgatgtaga acttgcatgt gagaaagcaa
    62581 aggaacatat ggattttata agtaaaaatt atagaaaaaa tgaaaattaa aagtttgtta
    62641 taaaataaat tattcttgca aatggtagat aatggtacta tcatataaat gtaaaactgg
    62701 tatgaccaca taccaatttt atagtttatt ataatgggag attaaaaatg gtaaagttaa
    62761 aagtaccgta ttcaaaacaa ggaatgattt tagaaatacc tgatgaacgt tttctcggtg
    62821 ttttggagtc aaaatcggat aattatatag aacataagac tcaagaagag atagttgaag
    62881 aatctatgaa taatcctata ggctctaatt ctctggaaga actggttaag gggaaaaaga
    62941 atgtagtcat aattacaagt gaccatacaa gacctgtacc aagtagaata actatgccaa
    63001 ttatattaag aaggattagg aatgttaatc cagaaattga tgtgaagatt atagtggcaa
    63061 ctggatttca taggccaagt acaagggaag agctaattta taaaatggga gaagaaatag
    63121 tagataatga agatatagtt atgcatatat ctactgatga taaatctatg tgtaaagtag
    63181 ggatattgcc ttcaggtgga gatttatata taaacaaact agcatatgag gcagaacttt
    63241 tgatagcaga aggttttata gaacctcatt tctttgcagg tttttcaggt ggcagaaaaa
    63301 gcgtacttcc aggaatcgca tctgcaaaga ctataatgta caatcactgt agtgacttta
    63361 tagatagtga taattcaaga actgggaaat tgaataataa tcctattcat gaggatatgg
    63421 tatatgcagc taaagttgca aagttagcat tcatattgaa tgttgtaata gataaagata
    63481 aaaaaataat tgcttccttt gctggtgatg tcgaaaaagc acatactaaa ggatgtagat
    63541 ttgtaacaga gttatcaaaa gtaaattcta taaaatctga tattgttgta actacaaatg
    63601 gtggatatcc actagaccaa aatatttatc aatctgttaa aggaatgaca gcagctgaag
    63661 ctacttgtaa agacggtgga gtaataataa tgatttcagc atgtaatgat ggtcatggag
    63721 gtcaatcttt ttatgaaaat gtagcaaatg cagattctcc aaaacaactt ttagataaaa
    63781 ttagaagtgt cgatagagta gatacgattc cagaccaatg ggaatttcag atactagcga
    63841 gaatattatc taaatatact gtgataatgg taacagataa gtgtaatcct gaaatgataa
    63901 aaaaaatgca tatgaaacat gcatttaact ttaaagaagc tttagaaatg gcgactagta
    63961 tagttggtaa ggagagcaaa gtagtagtta tacctgatgg agtatcagtt atagttaaat
    64021 aaaaaaggag tgtactttat ggaaattttg acatgtatta aacaagttcc tggaacgact
    64081 tcagtagaag ttgatgaaac tacaggagta ctaaaaagag atggagtaga ttcaaaaatg
    64141 aatccctatg acctatatgc tttagaaaca gctcttagaa taaaggaaga gaagaaagcg
    64201 aatctaaaag tacttagcat gggtcctcct caggcaaaga aggtaattga agaaagtttt
    64261 atgatgggag ctgatgaagg agcattaata agtgatagga gatttggagg agcagatgta
    64321 ttggctactt cctataccat atcacaaggt attaagaaga tgggaaaggt agacctaata
    64381 atttgtggaa aacaaactac tgatggtgat acagcacagg tgggacctga agtagctgaa
    64441 tttttagata tacctcatgt tactaacgtt acaaaattaa ttgaagttaa agatgaaagt
    64501 atagttgttg aaatagatat gccaaatgat ttacaagtat gtgagattga atatccatgt
    64561 ttaataactg tagaaaaaga catttttcaa ccaagactac cttcatttaa attaaaactt
    64621 aatactaaag atagagaaat acctgtatat agcttagatg actttgaaga taaagatgaa
    64681 aataactatg gacttaacgg ttctcctact caagttgtaa gaatatttcc tccaaagcca
    64741 aatacagata aaaatattgt aagaggaaat gcagatgaac taagttttgc acttgtaaat
    64801 aaattagagg aattaaagtt ggtgtaaggg ggagtaataa atgtcaaaga tagttgtaaa
    64861 tcaagataaa ataactgact taaagagaat tttagaaata tgtccttttg gggctataga
    64921 agaaaagtca ggtatagtag aaataagtgc tggctgtaag atgtgcaagt tgtgtgtcaa
    64981 aagtggacca aaaggcgcat ttgaatttat agagagtagt aaagtacaaa ttaataaaga
    65041 tgaatggagg ggaattgcag tatatgttga acatcataat ggaaatatac atcctgtaac
    65101 gtacgagctt ataggtaaag ctcgtgagat ggcatcaaaa ataaaacaac ctgtgtattg
    65161 tgtatttgta ggaaaagaca taaaagataa gtgcagtaat ttgatttctt atggggtgga
    65221 tgaagtattt gtatatgatg aagatgaatt taaagatttt aggatagaac catattcaaa
    65281 agcaatagaa aactttatag ataaaataaa accaacgata gtattagttg gtggaactac
    65341 attaggtagg tcattagctc caagacttgc cgctagattt agaacaggtc ttacagcaga
    65401 ttgtacaata cttgatattc aatcaaatac tgatttagac caaataagac cagcatttgg
    65461 tggaaatata atggctcata taaacacacc taataataga ccacaatttg ccactgtaag
    65521 atataaaata ttttcagcac cagaaaaaat agagaatact acaggaaaga taactttatg
    65581 taaagtagaa aaaaaagaac taaaatctaa aattaaggta ctgagtgtaa aagaaaaaaa
    65641 taaagaagtt ggtctggaag aagctgaagt gatagttgtg gcaagcagag caataaaaaa
    65701 acaagaggat atggagatga tatataaatt agctgataag ttaaacgctc aagtggcagg
    65761 aacaagacct gtaatagaag caggttggat agatgctaaa aaacaaatag gtcttagtgg
    65821 tagaactgta aagcctaaat tgataataac ttgtggttta tctggagctg ttcaatttgt
    65881 tgcagggatg cagggtgctg attatatagt agcaataaat aaagatgata aagcgcctat
    65941 acttgatgta gcacatctag ctttaatagg tgatatttat gatattattc ctaaattgat
    66001 tgaaaaaata gaaaataaca aagataataa tcaaaaatat atggcatcag cagctaaata
    66061 gggggataga aatgtataaa ttaatcgata aaaaagatat agatttttta atagatactt
    66121 gtggagaaga aaatgtatta gttggaagtg atataaatga agatttttca catgatgaac
    66181 ttggagggat tgagaagtac cctgaagttt tagtaaatgt acttgaaact gaacaagtat
    66241 ctaaaataat gaaatacgca tataaaaata atataccagt cacaccaaga ggtcaaggta
    66301 ctggtcttgt aggtgctgct gttgccataa atggtggaat aatgattaat ctatgtaaaa
    66361 tgaataaaat acttgaagtt gattatgaaa atttaacatt gacagtagaa ccaggtgttt
    66421 tattgatgac aataggtcaa tatgttcaag atagagattt attttaccca cctgacccag
    66481 gtgaaaaaag tgctacaatt gcaggtaata taaacactaa tgcaggtggt atgagagcag
    66541 taaaatatgg cgttacaagg gattatgtaa gaggacttga agttgtacta ccaaatggag
    66601 aaattataaa tgtaggtgga aaggtggtta aaaatagttc tggatatagt ataaaggatt
    66661 tattagtagg ttcagaaggt actttaggaa tagttactaa agctatatta aaattgcttc
    66721 ctttaccaaa gaaaagtata agtttgctta taccatttcc agatttatca atggcaatag
    66781 aaactgttcc taaaataata aaatcaaaat caataccaac ggctatagaa tttatggaaa
    66841 gagatgtaat attggcagca gaagaatttt taggtaaaaa gtttccagat aatacatcag
    66901 atgcttatct tttacttaca tttgatggaa atagcactga agatatagaa aaggaatatg
    66961 aaaaagtagc taatttatgt ttagaaaatg gtgcattaga tgtatttata tcagatacac
    67021 aagaaagaaa cgattctata tggtcagcca gaggtgcatt tttagaagct ataaaggcat
    67081 ctacgacaca aatggatgaa tgtgatgtcg ttgttccaag agataagata gcagagttta
    67141 taagatacac tcacgagctt caagacaaat taaaaataag aataaaaagt tttggtcatg
    67201 caggagatgg aaatctacac atatatattt taaaagatgg tatggatgat aatacatgga
    67261 aaataagatt aaaagaaact tttgactata tgtataaaaa atctagagaa cttagtggtc
    67321 aagtttctgg tgaacatggc ataggatatg ctaaaaaaga gtacttacat gaatcaaatt
    67381 cagatgctta tatgatgtta attaaaaata taaagttagc ttttgaccct aaaaatattt
    67441 taaatccagg gaaaatatat tagaaatatt aatttaataa tatttacaaa acaaaaaata
    67501 ttaaattaga tttaaatata atattttaaa ctttactttt aaatctgaag ctaaattgta
    67561 aaatttttag gatggcaata tttacttaaa tttagaaagt aacataatat ttaagttgat
    67621 gttgtcatcc taaaagcatg tgtacataaa taaagtaaga ctattgtatc ttatataata
    67681 aagagttaat aaaatgattt ttataaatat agttatttaa aaaaactact ttacatatat
    67741 tggatgagta taaaaatcca tagggccttt tactaaatct ttattgtttt tataatatat
    67801 tgaattatat atatttgtag cttttatatc ataacttatg agtgttttaa aaatcgtatc
    67861 atctaatgaa aatgatatat ttgaaaactt gtttattatt tttatttcag atttattttt
    67921 tatctctttt agaatttctc tacctttatc attaaaagca agtattctta tataaggtat
    67981 agtatctatg ttttttataa gttgcatgtc gcttttttta atacctaaca atatattgtt
    68041 tagagttcgt ttgattttgg ttaaagtgta tcgcttggat ttaattgcta attgtagctc
    68101 atgtagaaat tcagatgtaa agatatcttt atagattctg ttttctatgc cttcatttac
    68161 ttcaaaatac tcttttaaag tgtccatatc tctaagtata attgttttta aaatatcaaa
    68221 gaagaagtca tcaaacatag gtaaaaaacc attatctact ttttcattta ggatgttata
    68281 agttttttct ggaataacat tttttaaatg aaaaaggtct gtattttctt taagtgaagt
    68341 ccttatagca gtagcagaac aaatatcact ctcaatttct tcggaattat attctgattg
    68401 gaccctggag atagtaaatg gttttatact actgtttaaa tggatgaggt tttttatgta
    68461 ttctataccc agtatgttgt ttgatgaatt taatgttttt gataattgtt cctttgaata
    68521 attttgtata aaattatttt ttttgtcttg atgtatataa tcaaaaagtg cattagctct
    68581 agctgttgga aataacaggc catcatctaa atattttttt aaaagtaact taaattcatt
    68641 tggttcattt gctaaaattt cagctatatt ataaagaatt tctgtatttc cttcttcact
    68701 accaaaacat atagaattta tgcagtttag tgaatttaaa attgttatag caccatgaga
    68761 aaaaatttca gcactttgac aagcaaataa agttggtaat tctataacta agtctacacc
    68821 attttcgaca gcaatttttg ctctagtata tttatcaaat aaagctggtt cgcctctttg
    68881 tagaaaattt ccactcatta ttgctacagt atgtgttgca tttgtttttt ctatagattt
    68941 agataaatga tatatgtgtc cattatgaaa tgggttatat tcaactatta atccaagtat
    69001 gttcataaaa tactcctttt atctttaatt attttatat
//
LOCUS       DACTZW010000010        66676 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.010, whole genome shotgun sequence.
ACCESSION   DACTZW010000010 DACTZW010000000
VERSION     DACTZW010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 66676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66676
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.010"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            380..1576
                     /locus_tag="JAM15_03520"
     CDS             380..1576
                     /locus_tag="JAM15_03520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002842704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HAT6797340.1"
                     /translation="MKILVLNCGSSSLKYQLIDMNNEEVLCIGLVERIGIEGSILKHE
                     KAGRDDKYVVEQPMKDHKDAIALVLEAVAHPEFGAVKEMKEIDAVGHRVVHAGEKFAT
                     SVVITPEVEEALKECIDLAPLHNPANIMGIDACKAILPDVPMVGVFDTAFHQTMPKSS
                     YLYGLPHELYTKYGVRRYGFHGTSHNYVSQRAAEILGKDIKDLKIVTCHLGNGASIAA
                     VDGGKCVDTSMGFTPLEGLIMGTRCGDIDPAILPFLMRKEGLDADGLDKLMNKESGVY
                     GMTGISSDFRDIEDAAKNGDERAQATLEAYVKKVQKYIGAYAAEMNGLDVVVFTAGVG
                     ENGKAIRADIASNMEFLGMKLDKEANDVRGKETVISTADSKVKMLLIPTNEELMIARD
                     TLRLVK"
     gene            1669..2193
                     /locus_tag="JAM15_03525"
     CDS             1669..2193
                     /locus_tag="JAM15_03525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HAT6797341.1"
                     /translation="MKVSIEKINRKETDKIDLNFCEKIDTISYCDEIYKLVSPVNLKG
                     KVSKTNKGLYLDIDVNFTIVDNCSRCLKEVEIPLEYSIQGFLVKEEDYDEDEFEEFDP
                     FIFDGEEIDLIDIIEQTLDFNVPHKVLCSENCKGLCQVCGANLNEEECSCSEITNDEE
                     YIDPRFAKLKDLFN"
     gene            2218..2394
                     /gene="rpmF"
                     /locus_tag="JAM15_03530"
     CDS             2218..2394
                     /gene="rpmF"
                     /locus_tag="JAM15_03530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HAT6797342.1"
                     /translation="MAVPKRKTSKSNTKMRRAANSKMEATGFVSCPQCHEPKLPHRVC
                     PDCGYYKGKEVVSK"
     gene            2601..3158
                     /gene="fapR"
                     /locus_tag="JAM15_03535"
     CDS             2601..3158
                     /gene="fapR"
                     /locus_tag="JAM15_03535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription factor FapR"
                     /protein_id="HAT6797343.1"
                     /translation="MKKKSKAQRQKELIDMLKTDPFYTDEELSSLFDVSIQTIRLDRM
                     SLNIPELRERVKSIAETQSSKVKTLGVKEITGEIIDLSVGRLGISMLEVTQDMIYSKT
                     NTLKDTYIFSLADSLAMAIIDAPKVIMRVANVKSFKLIEQQDRLIAKAEVYRNIDKKH
                     YVKVVINNKAQEQIFRGKFIFEELD"
     gene            3169..4191
                     /gene="plsX"
                     /locus_tag="JAM15_03540"
     CDS             3169..4191
                     /gene="plsX"
                     /locus_tag="JAM15_03540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HAT6797344.1"
                     /translation="MKIVIDGMGGDNAPKSNVEGAVNAIKEYQVDLIITGDKDLLEKE
                     FSNYEFDRNKLEIVHTTEIIENEDKPVKAIRSKKDSSMVVALNLVKEGKADAIISAGN
                     TGALLAGGLFVVGRIKGIDRPCLCSAIPNVKRGMTLIADCGANADCKPKNLVEFAAMS
                     NIYSRKVLGLENPKVALANVGLEEGKGNDLVKRSYEEIKKLDLNFIGNVEAREVINAY
                     TDIIICDGFTGNILLKSAEGVALSVMSLIKETFMASTKSKIGALLIKDDLRKLKSFID
                     YSEYGGAPLLGLNGGVIKAHGSSDAKAIKNAINQGIKFSKGKVVEDINQFISKYNEEN
                     KNNEDE"
     gene            4217..5203
                     /locus_tag="JAM15_03545"
     CDS             4217..5203
                     /locus_tag="JAM15_03545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HAT6797345.1"
                     /translation="MNTKAGILGVGSYLPEQSYDNFHFEKIMDTSDEWISTRTGIKER
                     RFAKESEATSDLASKAALKAIECAKLNVEDIELIILATITPDMSLPSTACIVQDAIGA
                     VNATAFDISAACSGFVYGVTIAKQFVETGCYKNVLVIGAETCSKFLNYDDRTTAVLFG
                     DGAGAAVIGPVNEGGILSTHMGSDGKGKDCLKVPAGGSRLKASKETVEANLHTIEMAG
                     SDVFKFAVRKMAETSLRALEKANLNTTDIDYLVPHQANIRIIQASSKRLELDMKKVYV
                     NIDKYGNMSAASIPVALDEAYREGKIKKGDNVVLVGFGGGLTWGASVVKWTL"
     gene            5312..6241
                     /gene="fabK"
                     /locus_tag="JAM15_03550"
     CDS             5312..6241
                     /gene="fabK"
                     /locus_tag="JAM15_03550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HAT6797346.1"
                     /translation="MNKICKILNIKYPVIQGGMAWVATASLASAVSNAGGLGIIAAGN
                     APKEAIKKEIVECKKLTDKPFGVNVMLMSPFVDDIIDLIIEEKVQVITTGAGNPAKYM
                     DRLKEAGTKVIPVVPTIALAQRMEKLGATAVIAEGTEGGGHIGELTTMVLVPQVADAV
                     NIPVIAAGGIVDGRGIAASFALGASAVQVGTRFICSEECSVHSNYKNLVLKAKDRDAI
                     VTGRSTGHPVRTLKNKLSKEFLKMEQNGATPEELDKKGTGALRFATVDGDIEKGSFMA
                     GQSAAMVKEITPCKEIIEAMVNQAREIMPAIEL"
     gene            6257..7207
                     /gene="fabD"
                     /locus_tag="JAM15_03555"
     CDS             6257..7207
                     /gene="fabD"
                     /locus_tag="JAM15_03555"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HAT6797347.1"
                     /translation="MGKVALVFPGQGAQYVGMAKDLYENNAVAKSVIDEASDALNMDL
                     KNLMFNGNEEELSKTENTQPAMVTHSVAVLKAVQAQIDLKYNACLGLSLGEYSALVAA
                     DAIDFKDAVCLVKKRGKFMQETVPAGVGAMAAILGLDRNVLENVVKDIQGGIVEVANY
                     NSPGQIVISGENEKIEEAMVKCKEAGAKRAVKLNVSGPFHSSMLKEAGVKLASELEKV
                     NITKPKVDVVANVNADYYKNEGKDLLIKQVSSSVLWEDSIERLLNDGYDTFIEMGPGK
                     TLKAFIKKIASNKKANVNIYNIDGIDSLNEFVQNYRNGEI"
     gene            7207..7956
                     /gene="fabG"
                     /locus_tag="JAM15_03560"
     CDS             7207..7956
                     /gene="fabG"
                     /locus_tag="JAM15_03560"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HAT6797348.1"
                     /translation="MINLTGQVAVVTGGSRGIGKEIAKKLASFGADVVINYTSKEDEA
                     LKTKNEIESMGVKCTSIKCDVSKFDEVNQMIDSVVSEFGKIDILVNNAGITKDGLLMR
                     MKEEDFDRVIDINLKGVFNCTKAVTKPMMKKKYGRIINMTSVVGIMGNAGQTNYCASK
                     AGVIGFTKASARELASRNININAVAPGFIETDMTRVLSDDVKESTLANIPKKSYGKPE
                     DVANAVAFLVSDMSSYITGQVINVDGGMVMQ"
     gene            8010..8234
                     /gene="acpP"
                     /locus_tag="JAM15_03565"
     CDS             8010..8234
                     /gene="acpP"
                     /locus_tag="JAM15_03565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HAT6797349.1"
                     /translation="MFNKVVEIIIEQLGVEDKEITMETSLMKDLEADSLDAVEIIMAL
                     EDEFGIEIPDTEAENFKSIGDIVKYIEANK"
     gene            8263..9501
                     /gene="fabF"
                     /locus_tag="JAM15_03570"
     CDS             8263..9501
                     /gene="fabF"
                     /locus_tag="JAM15_03570"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HAT6797350.1"
                     /translation="MNKRVVITGLGCVTPLGTGKEEFWSNIKSGVSGIDKITNFDAST
                     YQTQIAGEVKNFHPEEYISKKELKRLDKFAQFAIVSAKLAVEDANLDLDKVDRERFGV
                     IIGSGIGGVEAIETQHKILLEKGNKRVSSLFVPMMIGNMAAGQVSIFLGAKGPNTNVC
                     TACASGTHSIGDAFKVIQRGDADIMVAGGSEAAVTGLAFAGFCNMKAMSTRNDDPKTA
                     SRPFDKDRDGFVMGEGAGIVILEDLEHALARGAKIYAEVVGYGLTADAYHMTTPAENG
                     EGAARSMNMALKDGNVPLEEVDYINAHGTSTYYNDLYETMAIKTVFGEKAYDLCVSST
                     KSMTGHLLGASGAIEAVVCAMSIEDSFVPPTINIQEVGEDLDLDYVPNQGKEKNIRYA
                     LSNSLGFGGHNATIVLKKYV"
     gene            9727..11445
                     /locus_tag="JAM15_03575"
     CDS             9727..11445
                     /locus_tag="JAM15_03575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HAT6797351.1"
                     /translation="MNFRLPKKRLPKKIIFICIILISIILFIKYDQNGLKEREIINKG
                     KYMSESLVADKEYDEAKKVVKTSFESIPEKKYNKVYNEVWDMLKTISYVPDGTKIVIN
                     SLEKMRESDVKLSDECRFNIEKRLASVYIMDNNYSKAVDLTVKSIKLAEKLGNNYEKA
                     RLDVDLASIFLKIGSYETGEKLIKDSFKIDIDEGEKNGMVRLYAIINLAEIYVEEGEY
                     DKAIEISSRIKDYKKFVNTDNYNDFDIMASIMKSNAYVGKNNIQKAKTFLEKADYLIK
                     SDRTVYILDKDMYYYMAMGNLEYKSENYNSAIDNYKKSLEISTKRKLTQEKIKNLNKI
                     LNIYEKQGNIESLNEYQKMLINEYKENKSIRDSETSFYIIDKVSNESKLFEKTKKEIK
                     YYKILFTVILIAILGSTFLYNRLKYFKAQNLHDGLTNVYNRKSFDIMYEKYREKDDNF
                     ALVMIDIDNFKLINDNYGHKFGDTVIKGITNTICVMLEQDDKVFRYGGEEFSVLIRNK
                     SGEEVADIIDNIRVAIANKKWNDDVTVTISAGVSHISDSKDVLEEADKNLYKAKQLGR
                     NKVVYK"
     gene            11476..13476
                     /locus_tag="JAM15_03580"
     CDS             11476..13476
                     /locus_tag="JAM15_03580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAT6797352.1"
                     /translation="MKQSIAIVTDKITKLSSFLEENIRLVLGNYIDINHYYLEVLKEN
                     DKIQGDFVLVMNDDRLNSMRKHLVQDSKIIVIRRTLKENEIYGLFSIPNGTEVLVVND
                     TKETTLETISLFYKIGVKNLKFTPYIKGKIYKNIDIAITPGVKEKVPSYINKVIDLGN
                     RYIDISTFIEIINGLRIDVKEIRKNLMAYSESLISLDNGVKDNYRQLFLKIEEQDVIL
                     NLSKDGIIFTSADGIINTFNKEALKILGINENPQGKNIEDIISEDLNILLEDKEIIDE
                     VVFTNKKYINVNKKSIFSMGNKAGIYYNLQEITYIKKLEQNLTNKLREQGQIARYTFK
                     DIKTKNKNMVKCVELAKKISKSDLSVLIIGESGTGKELLSQSIHNASNRSNQPFIAVN
                     CAAVPDSLLESQLFGYEKGSFTGALREGKKGLFELANNGTIFLDEIGDMPPLLQTKLL
                     RVLQEKQVMPIGSHNVINIDVRVIAATNKNLPKMIREGKFREDLYYRLNVLPIDVPSL
                     RNRKEDIITLMNFFLKNNIRLSPEVITILEKYNWPGNIRELQNVASYVSLMCDSMVFR
                     DDLPPYIRIECANNYEDGFGYTKKEFEEILRILYERRESSSGVGRGFIIEKLIQEGIE
                     ISESKVRKVLSYLSECGYISSKSGRGGSQITSEGIKLYNNIN"
     gene            13824..14069
                     /locus_tag="JAM15_03585"
     CDS             13824..14069
                     /locus_tag="JAM15_03585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HAT6797353.1"
                     /translation="MKYKTTGTCATEIEFEVKENKVINVNFIGGCDGNLKGLKVLVEG
                     MNIEDVIQKLKGIECKTKQTSCPDQLSLALENYMNIK"
     gene            14104..14829
                     /locus_tag="JAM15_03590"
     CDS             14104..14829
                     /locus_tag="JAM15_03590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HAT6797354.1"
                     /translation="MKPIIGILGNLIIMENGMFPGLERSYVNNDYINAVLKGGGSPVI
                     IPVNTDKEVIKKQIEMVDGVLISGGWDVNPQLYGEETREETTFIYPEVDEFDLIAISI
                     ALELKKPILGVCRGLQILNVSLGGTLYQDNNLIEGSYIKHTQSSKRHVATHKVDVKEG
                     SILEGILGKQLLTNSYHHQSVNQLGKGLKAIAYSKDGIIEAIEKEDENFVVGIQWHPE
                     MMVDYCDKMEKLFKYFINICSNL"
     gene            14851..16164
                     /locus_tag="JAM15_03595"
     CDS             14851..16164
                     /locus_tag="JAM15_03595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAT6797355.1"
                     /translation="MNEKNKMGLISIILLGINAVVGAGVFLLPGDAMKSFGVASIFVY
                     IFDMLLVLSMAFCFAEVAGKFNKNGAAYVYTKEAFGDFCGFEVGLMKWVIGCISWGAL
                     IVGFPTSLSAVWAPAGEPHIQKIIIVVMIVGLTIINLLGVSLSKIVQNVITVGKLIPL
                     ILFIGIGIFFIKGVNFTSSTMVPPGAGATEFGAAALLMFYSFTGFESIAVAAEDMENP
                     QKNIPIAIISVIVIASIIYILNQVVCVGILGDSLSSTSTPVADAARICFGNMGAGLVT
                     FGTLVSVGGICMCGAFVNPRSCVALADDKMLPRIFARKDKKGTPYVAIIATMLITIPI
                     ALSGSFAELAAISAVARFIQYIPTSLSVLVFRKKRPELVGTFKTPFGAVIPLIAVCVG
                     TWLLFQASMHQLIMGLGALAIGVPLYFIMKSYNRKVYGENLKKIV"
     gene            16370..16909
                     /locus_tag="JAM15_03600"
     CDS             16370..16909
                     /locus_tag="JAM15_03600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAT6797356.1"
                     /translation="MPTITLKNGVDVLIREGVREDAQSIIDFYNEVGGETHFLSFGKD
                     EYKISLEEQENAIESAKASDNSVKLIAFIDDEIVGIATIDSNQKAKGKHVGVLGIVVK
                     EKYWGIGLGKRLMLDLIEWCKSNGITKKITLVTNEENYNAIGLYKKVGFEVESILKKE
                     CYYNGVYTDLIGMSLLLGI"
     gene            16998..18983
                     /locus_tag="JAM15_03605"
     CDS             16998..18983
                     /locus_tag="JAM15_03605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HAT6797357.1"
                     /translation="MKNLCKISDDYLNSKLKYLKLLSKQYPSISKASTEIINLEAILN
                     LPKGTEHFITDVHGEYEPFVHVLKNGSGVIKRKIEELFSNTIRDSEKKMLATLVYYPE
                     QKLDLIIKQEENIDDFYRINIYRLIELCKYASSKYTRSKVRKLLPENFKYIIEELLHE
                     HVKSEHKEEYYKSIVETIVDIGIAKEFIIAISTVIQKLVVDRLHVIGDIYDRGPRPDI
                     IVDKLIEHHCVDIQWGNHDILWMGAASGEKTCIANALRISARYANLDIVEDIYGINLL
                     PLATFAIEMYKDDPCKEFIPKVNDQSVTTTEKSLMAKMHKAISIIQFKLEGEVIRRRP
                     EFEMEHRLLLNMINYDEGTITLKGKTYKLKDTYLPTIDKKDPYKLTMEERNVIDKLVS
                     SFRGSEKLQKHVSFLFSKGSIYLKANSNLLIHGCVPLNEDGSFMSMNIMGKEYKGKAL
                     MDKMESLAREGFFFKDKAEEKLYGMDIMWYLWTGKCSSLFGKDDMTTFERYFIEEKET
                     HKENKNPYFKLRENEMACKRLFEEFDLELDESHIINGHVPVESKNGESPIKANGKILV
                     IDGGFSRAYQKTTGIAGYTLIYNSRTLQLVSHEPFNSAEEAIANESDILSTTVVVEHK
                     AKRKMVRDTDEGVKIQEEIEDLKLLLMAYKKGLIKEM"
     gene            19207..20175
                     /gene="spoIIIAA"
                     /locus_tag="JAM15_03610"
     CDS             19207..20175
                     /gene="spoIIIAA"
                     /locus_tag="JAM15_03610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AA"
                     /protein_id="HAT6797358.1"
                     /translation="MNKLSDEIINSLSTTIREKVEKVSNNNLNIEEIRLRSQKPLILN
                     ANSKDYFYNQKTMTLDLNQQNSYVVTREDVEQTFQIICKYSIHSFMDDIKKGFITLRG
                     GHRVGLVGKAIVEDGQVKNIKHISSLNIRVSREIIGCSDKILSHIIKGKNQINNTLII
                     SPPQCGKTTLIRDIVRNLSNGNEDYGFKGLKVALVDERNEIAGAYLGVPQMDVGIRTD
                     IIETCPKDLGITMLLRSMSPNVIVTDEIGSEKEIKALYTALNGGIGLITTVHGDSIDD
                     IQNRKELNRLLDKELFKKVIILSAKRGAGTIEKIYDLEEKRWYFAN"
     gene            20165..20686
                     /locus_tag="JAM15_03615"
     CDS             20165..20686
                     /locus_tag="JAM15_03615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AB"
                     /protein_id="HAT6797359.1"
                     /translation="MQIKIIIIALLVGSSYLIGEQIYKTYTRRHKQLNDLIRVLEILR
                     MDLSFGLYTLEEIFNRIGGNKEFCFWKFFYQISEGLHNEQSKTLEIIISENIDVLSKE
                     TYLGNKEIEELKNLILTLGKSDIESQQRMIDLSIENLKKQTYETKEDINKKGVLYKKL
                     VTFIGIGICIILI"
     gene            20703..20900
                     /gene="spoIIIAC"
                     /locus_tag="JAM15_03620"
     CDS             20703..20900
                     /gene="spoIIIAC"
                     /locus_tag="JAM15_03620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AC"
                     /protein_id="HAT6797360.1"
                     /translation="MEISLILKVAGVGILISVLNMILEKTDRKDWAGLTTLAGVIIVL
                     GMVITEISDLFNTVRTMFQLY"
     gene            20916..21302
                     /gene="spoIIIAD"
                     /locus_tag="JAM15_03625"
     CDS             20916..21302
                     /gene="spoIIIAD"
                     /locus_tag="JAM15_03625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AD"
                     /protein_id="HAT6797361.1"
                     /translation="MEIMQLIGIAIISTTLCLVIKKDRPEIANFIAIITGVIILLSVM
                     FKLNFIVDSIQDLANKANIPTMYISLIIKLIGIAYLMEFAIQLCKDCGEGNIASKLEF
                     GGKIIVMSMSFPILLSIVEMVVNIIP"
     gene            21387..22592
                     /gene="spoIIIAE"
                     /locus_tag="JAM15_03630"
     CDS             21387..22592
                     /gene="spoIIIAE"
                     /locus_tag="JAM15_03630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AE"
                     /protein_id="HAT6797362.1"
                     /translation="MKKRFLPMIIGFLFTFFFVNIFAIMIFANEVPSSEDKEYGETKN
                     SIDKYIDGQLDKLDINEIQDYINKEIVINDVNLKSFVKDLISGEKNILDLFNKDGLKI
                     LMFDEFKASLKVVAVILVLALLSSILKSLENSFSSGAVSQIATYIIFITMVSLTLIGF
                     KDVLQICYDAIDHTVGLMQVIMPILITFLLLIGFPITSTTLNPIFIGGVTFINVFFKN
                     FLFVSITVAFGILIINNLSKNIRLKRFFSFVKQINYVSIGAMFTVYLGLVSIQGLYVT
                     SFDKFSVKTAKFAIGNFIPVVGGFVSDSVDILLSSSQLIKNIFGGIGLILLVGICLLP
                     VIKILSVIVVYKLAAIIVEPVGEDGISNFLNEVANLMIIMLASVIAITVMFFVTVAIL
                     TSISVVSQG"
     gene            22652..23269
                     /locus_tag="JAM15_03635"
     CDS             22652..23269
                     /locus_tag="JAM15_03635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AF"
                     /protein_id="HAT6797363.1"
                     /translation="MLEGIKAWIVSVLIGAFIVNIVDMILPSSKIKPYVNLVLNFMFV
                     FIVITPVVGFFSKDMSLEDRILKSMGNYNKQYVDSTNALAKETGNNSLSKGYEDGLKE
                     VLKLKLDEYGYDLEDIELNGANINNIKIKEKNNSAKSNNSSNEENKNNSTKREEENIN
                     SNDKENSKQVFKKGTEYGLNLNEEKLKNDLIKVLDVSIEDIQIDK"
     gene            23281..23835
                     /locus_tag="JAM15_03640"
     CDS             23281..23835
                     /locus_tag="JAM15_03640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AG"
                     /protein_id="HAT6797364.1"
                     /translation="MLKNLNDKDKRKVYSLITIAGICVVSLVLLSCFPNSKSDKQVGK
                     TETNKNAEKQVTKKQEKDDLESKLTAILSKIDGAGDVDVMVTFESSEEIQPAFNSNNT
                     TETTEEKDAQGGERTVTTSSENKTMITSNSSDPVVIKTTEPKIKGVIVVASGASDPSV
                     KETLYSAVQTSLQVAGHQVEIYSK"
     gene            23862..24551
                     /locus_tag="JAM15_03645"
     CDS             23862..24551
                     /locus_tag="JAM15_03645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIIAH-like family protein"
                     /protein_id="HAT6797365.1"
                     /translation="MKFNYKGRGFVIITLTAMLVVVGTVNYQLSKKSLLETSKEFKAY
                     EEAQLQKNTDDSDSSKTEDSSNVDKQGGKESADIDIVDSKASKVKEKATETSKEIKAQ
                     LSSEKNMKKASYILDMKMNREKQRNELVQDLNEMINNPSTTEESRKEASNMKLNIVKI
                     QEKELQIENLLSTKGYEEALVYISDNKVNVVVNEAKLEKKDAAKIFDLVAEQANVKYE
                     NIKLTNNNSNK"
     gene            24661..25023
                     /locus_tag="JAM15_03650"
     CDS             24661..25023
                     /locus_tag="JAM15_03650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAT6797366.1"
                     /translation="MEDNKFGQVKISNDVIATIAGLAALEVEGIETTATLTDKLLKNN
                     GVKIQIEEEDVNLDVMVTIKYGMSIPDTAFKVQENVKNTVETMTGLKVSQVNIHIQGI
                     SFKKDKVDKEEAKATKKN"
     gene            25108..25614
                     /gene="nusB"
                     /locus_tag="JAM15_03655"
     CDS             25108..25614
                     /gene="nusB"
                     /locus_tag="JAM15_03655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HAT6797367.1"
                     /translation="MKKDRAQKSTTREYIMKLIYQININKEDFETLEDKVDNFLKDNS
                     EHIINRYKELALQYSKNTNLKLEDTEIEDVIDKKYINTVCKALKENHDKIDELINKHA
                     KNWTVDRMPKVDVSILRLSVCEILYLDTPNKVSINEAVELAKIYCDDKSPKFINGILG
                     SVVDEIGK"
     gene            25598..26668
                     /locus_tag="JAM15_03660"
     CDS             25598..26668
                     /locus_tag="JAM15_03660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-sialoglycoprotein endopeptidase"
                     /protein_id="HAT6797368.1"
                     /translation="MKLGNNIIIGIDTSCYTTSIAAISLDKKVIFNEKIMLEVRDNSK
                     GLRQSEAVFQHINNLGILSDRIKSFKDKFNVEGVCSSKKPRPVENSYMPVFNVGHNFG
                     KLLSSIYGCRFYETTHQENHIEASLLNNKLKNNNKFISVHMSGGTTEILLTSKQDSHH
                     NVCDTNLGKIAKISIKKDDKSKLYNNFGYNIDIIGGSKDISFGQLIDRVGIKLGYKFP
                     SGKYLDENALNCNLKIESGLKTSVRDGYMNLSGLENQVNKIINDNGDNTNQKEYISKL
                     VLDSVVRNMFKSLVYLCETYNVNEVVFAGGVSASKYILRELSMKLRKKHIEAYFTEPQ
                     YSTDNAVGCAIIGLNNFLGERV"
     gene            26665..27870
                     /locus_tag="JAM15_03665"
     CDS             26665..27870
                     /locus_tag="JAM15_03665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HAT6797369.1"
                     /translation="MKLRALDISEANSYIKRILINDPILSNLKVKGEISNFKVHSSGN
                     VYLSLKDETSKLNCVIFKSNFNRNLKLDNGVKIIANGYISVYERDGAYQLYINEIEIE
                     GIGNLHIEFNRLKEKLNKEGLFDPKYKIPIPKMPNSIGVITSPTGAVIRDIINVIKRR
                     YPKVNIKLYPVMVQGDKSAEEICEAIRFFNHMKNVDTLIVGRGGGSIEELWSFNDEMV
                     AREVFNSQIPIISAVGHETDFTICDFVSDMRAPTPSAAAEIATPSLDDINYKLGNIKS
                     RMSKSLTNQIELDQYRLETVFNKINNYLDSYTIKDKVIQLDKIYDKIIFGIENNLKLE
                     DEKLVKIGALLHNLSPLATMDRGYSITQKNGKVINSIKGLKIKDSIDIVLKDGNLECM
                     IDKIENKEG"
     gene            27872..28087
                     /gene="xseB"
                     /locus_tag="JAM15_03670"
     CDS             27872..28087
                     /gene="xseB"
                     /locus_tag="JAM15_03670"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HAT6797370.1"
                     /translation="MNLTYEEAYKRLESILSELESKNASLDESLSLYEEGISLYKHCN
                     KLLDDAKLKISKFNQLGIEEDFKIEEE"
     gene            28090..28977
                     /locus_tag="JAM15_03675"
     CDS             28090..28977
                     /locus_tag="JAM15_03675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HAT6797371.1"
                     /translation="MEFKQCLKEKASFVEKVLKEYMPKEEGYQKTVIEAMNYSLSAGG
                     KRLRPILTLEACKIVGGNEDEAIPFAIAIEMIHTYSLIHDDLPALDNDDLRRGRPTNH
                     KVYGEAMGILAGDALLNYAFEVMLAGSINKENPEKYLKAINEIAKGAGIYGMIGGQVV
                     DVESENKQIEKEKLDYIHMNKTAAMMVGCMRAGATIGGANSEQMEEITKYAKNIGLSF
                     QIVDDILDIVGDEAKLGKKVGSDIENHKSTYPSLLGLDKSKEIAHNLIDEAKKSIEKL
                     SDDVDFLKGLAEYIIDREY"
     gene            29007..29444
                     /locus_tag="JAM15_03680"
     CDS             29007..29444
                     /locus_tag="JAM15_03680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divergent PAP2 family protein"
                     /protein_id="HAT6797372.1"
                     /translation="MDFFSEIFNNGALGISLIACFLAQFIKIFTGKEKRIELSRILIS
                     GGMPSSHSSFVTSLATVVGIEKGFNSTDFAIITVLALIIMYDAAGVRRAVGKQATILN
                     QMVADIQHGKHIEQKKLKELIGHTPLEVWFGALLGIVTALILM"
     gene            29478..31343
                     /gene="dxs"
                     /locus_tag="JAM15_03685"
     CDS             29478..31343
                     /gene="dxs"
                     /locus_tag="JAM15_03685"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HAT6797373.1"
                     /translation="MYKYLDKVNSPKDIKNMSIEEMDLLAKDIRKFLVKSVSKTGGHL
                     ASNLGVVELTLALHKVFDSPKDKIVWDVGHQSYVHKIVTGRKDCFVSLRQFNGLSGFP
                     KENESPHDIFDTGHSSTSISIATGIACARDIKKENYSVISVIGDGSITGGMALEALNQ
                     LGYIDTNMIVILNDNEMSIDKNVGGMSKYLSSIIRNSTVEKMTDEVDKILNVTQTGEI
                     LSKTAHRFKDKLMYSFSPQDCSFFDSLGIRYYGPIDGHNTKELIDILRKSKHKKGPVL
                     LHVITKKGKGYRFAEEQPDKYHGVSKFDIKTGVTSAKVKSMSISVGEKLVDMANNNED
                     IVAITAAMPSGTGLNLFESAYPKRYYDVGIAEQHATGFAAGLAKNGMKPYFAVYSSFL
                     QRAYDQVIHDVCITKKPVTFLIDRAGLVGNDGETHHGMFDLSYLNSIPNIVVMAPKDT
                     REMELMMDLSLKLDCPLAIRYPRGSSYYLDKGEYGEIVLGKYEVLDDGQDTVILCIGS
                     MVKHALEAKEILSREGINPTIVNARFLKPIDEGMLKALLKNHKNLVTIEDNIVTGGFG
                     SRINKFIIDNEYNVNILNIAIPEEFVKHGNIDELYDFVGLSPKSIADKIRKLVIE"
     gene            31476..32288
                     /locus_tag="JAM15_03690"
     CDS             31476..32288
                     /locus_tag="JAM15_03690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family rRNA
                     (cytidine-2'-O)-methyltransferase"
                     /protein_id="HAT6797374.1"
                     /translation="MKKRIDLLLVEQGYFESRERAKKAIMAGLVFVDNQRCDKAGTEV
                     KEDCSIEVKGNPIPYVSRGGLKLEKAMKNFNLTIDGKVCMDIGASTGGFTDCMLKNGA
                     IKVFSIDVGYGQLAWKLRQDDRVVCMERTNIRNVTIEDTKQFADFASIDVSFISLKLV
                     LPKAKELIRHDGEVVALIKPQFEAGREKVGKKGVVREKSTHIEVIKMISDFSVENGFE
                     ILGLDFSPIKGPEGNIEYLIHLRNGNEGYEFDGETYNNKIVEVVEASHNLDK"
     gene            32308..33987
                     /gene="recN"
                     /locus_tag="JAM15_03695"
     CDS             32308..33987
                     /gene="recN"
                     /locus_tag="JAM15_03695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HAT6797375.1"
                     /translation="MILELYMKNCALVEELRLNIDKNLNILTGETGSGKSIIIDALGL
                     CLGDKYDRSFLRKGTDKGLVEAVFFSDNRYLKKILEENDISMEDDNLLVITRLIYSDG
                     KSTARVNGRTVKVSLLKEIASTLIDIHGQHQNQALFNKDTHLKFLDLFGENELEEFKI
                     AYKNVYHKYSEVKKALNCLTENKDEMQIQREIDLLRFQINEIEAANLNKNEYEDLLKQ
                     REVYRNSEKIYNNLNSSYSKLHNGEYNVIDLIGLASKELNDISKYDSVLSEYSDTVER
                     IMYELQDISGEIRNYKDNIDFEPYELEQIELRIDEINNLRRKYGDSIDDIFEYYGKIK
                     DRLDEILNRDERVEQLKSKLMNIEEDLKIKASKLTKARIEVATTLEKILLDELKSLNM
                     KNVMFKVNFEKGPFTLDGVDDIEFMISFNLGEDIKPIYKVASGGEMSRFMLAFKTILA
                     DIDDIDTLVFDEIDTGISGIAAQIVGEKLSDIAKKKQIICITHLPQIAANADTHYCIE
                     KDTSNNRTFTNVSKLNESQRKNEIARLIAGNNITEKTIEHASEIIELAKKC"
     gene            34202..35068
                     /locus_tag="JAM15_03700"
     CDS             34202..35068
                     /locus_tag="JAM15_03700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797376.1"
                     /translation="MNKKDTMHLIFIIVIFILLWYIVVAVSEINKNIESCSNKLDYLS
                     QELMSTKSDISNTINEEMSKSYITKSIDLKVKKIEKKECIIDIDVQLSKLGKNGKVFF
                     MYKEDSDKWNETEMTKHGELSYACEIKINTGSEYDYKVVTSGAISESSDVQKLTKSDY
                     MPEQPIFNSGIRDNREYFIEIVENSNLFNHESEKSKNKVYDNIRLEKVDIIVNEGKKD
                     TIYKAKLAEGLDDGKTNNSNRNQVNYEVSFPKRDIDDIIYIKAKLTYNNGVEYTKDIT
                     EDITMGLQDLEK"
     gene            complement(35159..35650)
                     /locus_tag="JAM15_03705"
     CDS             complement(35159..35650)
                     /locus_tag="JAM15_03705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAT6797377.1"
                     /translation="MADKMAQNITLQFIEEKDLENLENVKLLFTEYSNSLNIDLCFQD
                     FNNELKTLPGKYKKPSGSLILAFVDENLAGCVALKKLEGKICELKRLYVRNQFRGLKI
                     GKILLEEIIVEAKKIGYTHMRLDTLPSMKSAQGLYEKFGFYDIEPYTYNPIEGARYME
                     LKL"
     gene            complement(35711..36151)
                     /locus_tag="JAM15_03710"
     CDS             complement(35711..36151)
                     /locus_tag="JAM15_03710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAT6797378.1"
                     /translation="MKLNVRIADINNWHDLISLSVDKSQLDYIESNALSIAESKFITA
                     WVPVGIYDENSLIGFAMYGRLEDDRVWLDRFMIDSKYQGKGYGKASLDFLVNHLKNEY
                     NCDELYLSIFEDNKMAIKLYKDFGFEFNGELDYGGEKVMVLKSN"
     gene            36312..37370
                     /locus_tag="JAM15_03715"
     CDS             36312..37370
                     /locus_tag="JAM15_03715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S55"
                     /protein_id="HAT6797379.1"
                     /translation="MNKINKNFKNIWIILGAVSIFTIVIIFNKNCNVNKETQIEAFTI
                     KNHDKKFVYPMGNIIGVKANTDGVLVLGYEEEDVDYIGGIQIGDNIVKIDNKRIKNSQ
                     DVSEILNNIKKSKVEVTFERKNTYKTEVIETKKENGKYKLGLWVRDKISGIGTMTFYD
                     PSMEKFKAIGHAIKDSDTNELLKIKQGYIYKPEQLKIVKASNEKVGKIKGDFNDSNLM
                     GNFSNNSELGISGNITENHNKEFNVANKEKQLIEVGRPQDVKIGDAVILFEDKNKNIT
                     SYDIKIESIVYDKGNYRDMVIKVVDDKLLEYTGGIVQGMSGAPIIQNNKIIGAITHVF
                     RDNPKKGYGIFIDEMIKL"
     gene            37512..38336
                     /gene="spo0A"
                     /locus_tag="JAM15_03720"
     CDS             37512..38336
                     /gene="spo0A"
                     /locus_tag="JAM15_03720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcription factor Spo0A"
                     /protein_id="HAT6797380.1"
                     /translation="MGGFLVEKIKIVLADDNKDFCQVLKEYLSNEDDIDILGIAKDGI
                     EALDLVKKTQPDLLILDVIMPHLDGLGVIEKLNTMDIPKMPKIIVLSAVGQDKITQSA
                     INLGADYYIVKPFDFVVFINRIRELVSNRVTQVEPKPRPVQETQMTRSDFVKNVGNIE
                     TEITNIIHEIGVPAHIKGYLYLREAIKMVIDNVELLGAVTKELYPSIAKKFNTTPSRV
                     ERAIRHAIEVAWSRGKVDTINQLFGYTVHNTKGKPTNSEFIAMIADKLRLEHSMVK"
     gene            38749..39870
                     /locus_tag="JAM15_03725"
     CDS             38749..39870
                     /locus_tag="JAM15_03725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797381.1"
                     /translation="MRVEAPIKVDRKTKKLAKRVESGEIAVINHIDIDEVAANSLVEA
                     KIKLVINAAPSISGRYPNKGPGILTENNILIIDNVGEELFEELKEGETIEVVDGKIYR
                     KGKFLGAGEVLDKYEVSHQIKAAYENLAVELDRFIDNTIDYAKKEKGFILGEVEIPKV
                     KTNYANKHVLIVVRGQDYKEDLSTMLSYIEEVKPVLVGVDGGADALIEFGYTPDVIVG
                     DMDSVSDEALKKASEIVVHAYTDGRAPGLKRVEELGLDAVVFPAPGTSEDIAMLIAYE
                     YKAELIVAVGTHSNMIDFLEKGRKGMASTFLVRLKIGSKLIDAKGVNLLYRSKLKIKY
                     IWALIATALFPVLVVASLSPGVQQFIQLMQLKFRVLLQM"
     gene            39888..40763
                     /locus_tag="JAM15_03730"
     CDS             39888..40763
                     /locus_tag="JAM15_03730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper transporter"
                     /protein_id="HAT6797382.1"
                     /translation="MHINMKYYIVTIGAIFIALGIGMLVGFNLNNNQQLSEQQANIIN
                     DLDDKFNILKEKNDKLDSDLASVNRDYEEAVNFINKNVDKILAGSLNGKSIGIISANE
                     NDDYTKNIEDIINKSNGSIAFNIVLKENITNPEKLKEMSTKLGTDVKNANDAVNYIID
                     TLKKEDASDILTYLQELDVIKFNSLGNTYLKYDSVVIAGGNDAKDSTKQFEKIEKFVV
                     SKLKSENKYLVEVQNTGVKTSYVELYSKNKVATIDNIDEGIGSISLAILLQQGNIVGN
                     FGRLDTATSLLPSIK"
     gene            40787..41479
                     /locus_tag="JAM15_03735"
     CDS             40787..41479
                     /locus_tag="JAM15_03735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAT6797383.1"
                     /translation="MDSYISIIIPAYNEESRIKYTLESILDIKQINEIIVVDDGSIDN
                     TAKVVSELENAKIKFFKLDKNRGKGYALNYGIKLAMKNADIIGFLDGDLGSSAKEVEK
                     LIVPILNGEADVTIAKFPPAKRKGGLGFVKGLAKNSVFEMTGVELDATLSGQRIFKRE
                     VLEKFDEIPFGYGVEVGMTIDILKYGFKIKEVLVNMTHNETGRNLKGFIHRGKQYYHI
                     KKVLGQKKKEWR"
     gene            41487..42311
                     /locus_tag="JAM15_03740"
     CDS             41487..42311
                     /locus_tag="JAM15_03740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HAT6797384.1"
                     /translation="MKDYILYTILLLTGLFGTYAVIPLFKNLLINGNVLRPNYKKDMI
                     PVSMGIVFLPMIVINGIILAFFTTEFKDLAYIFMFMFGMISMFFAGILDDVIGNRDVS
                     GLKGHFKSLFKGSLTTGGFKALFGGFVGLIVSVAISKDIIDIIVNTLIIALSTNLMNL
                     LDLRPGRAIKAYLFIMVIIFLTLTGFVQVLPLLIVPNVLAYFNYDLKARAMMGDTGSN
                     VLGISIGMLISFGYPFNIRLGWLIFVVIMHIFTEKYSLTKIIEKNKLLNFIDKLGR"
     gene            42316..43383
                     /locus_tag="JAM15_03745"
     CDS             42316..43383
                     /locus_tag="JAM15_03745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3866 family protein"
                     /protein_id="HAT6797385.1"
                     /translation="MISKRVGIVESIVSQTETLDDIRVNINGKIQRAYNYPKISGTIN
                     IGDEVVLNTTAVELSLGTGGYHFVITNLNNIESTLTEGGHIMKLRYTPLQIKVDSVEE
                     QESIYHDKFANFKGLEGLSVVVGTLHSMLTPFAASFKRNNPNKKLVYIMTDGASLPIY
                     LSKNVDTLKEKKLIDSTITIGNAFGGDYECINIYTALITAKEILKADAVFVSMGPGIA
                     GTGTKYGFTGIEQGSILDAVKKLEGRAIAIPRISFADKRERHQGISHHSMTVFKEIVN
                     VNVDIPITIYDDEKLNFIKEQINLNGLDKKHNIIYIDNNKTKEDLDYFNLKVKSMGRN
                     YEQDEAFFKAASTAAYYLMEV"
     gene            43385..43921
                     /locus_tag="JAM15_03750"
     CDS             43385..43921
                     /locus_tag="JAM15_03750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HAT6797386.1"
                     /translation="MVLEEKTISSDRVYTGKVITLKVDTVEIPGQGYQKRELVEVGGA
                     VGIVAITDDNKVVLVKQFRKPIEKPIFEIPAGKLEKNESPKECAERELKEETGYSAKN
                     IKLIHKFFTSAGFSNEIMFVYLATGLTPGENNLDADEFLDVYEIELEEAYNMVLKNDV
                     EDAKTSIGLLLVKDMFKN"
     gene            43989..44594
                     /locus_tag="JAM15_03755"
     CDS             43989..44594
                     /locus_tag="JAM15_03755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797387.1"
                     /translation="MRRTYRKNDFRELNRQIIIIGLLFMMSIVVGSYINKILPGSSNN
                     ILNNINPAVEYYNLNISIKDTVIQNLKSDAIFMGSIALLSLFVVTIPAVLVAFVLKGM
                     SIGYTINSCILALKFKSIKMILIILFKNLIIIPCAIILALISLSYFKEMVYEFKKKNR
                     KNMQFLIKRYILNIIIIIALSLGLQLILNTVSIGIIKFLAK"
     gene            44606..45520
                     /locus_tag="JAM15_03760"
     CDS             44606..45520
                     /locus_tag="JAM15_03760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAT6797388.1"
                     /translation="MDIIEGYIDYIKDKKKLSENTVASYFMDIKKYMEYINQKSIKLV
                     DIVENDIISYLIKLEKDNVSIATIARMISSIKSFHDYLFLNHICTNNPAKDIKKPKIK
                     KENINILTEEEIERLLNFPKLTTPKLIRDKAIFEVLYGTGIKVSELVEMNIEDIDLDI
                     DYIYCNSCCKNQRVIPLCDITKLYLEKYLKEARPKMAVEGEKSLFVSSLGQRFTRQGL
                     WKVIKKYSNLANIDKNINPTMLRHSFAIHLLNEGANIAVVSKILGNVNLSSLQVYLNH
                     IDKNVRREIKEKHPRNDVDVELQKAEAK"
     gene            45562..46734
                     /locus_tag="JAM15_03765"
     CDS             45562..46734
                     /locus_tag="JAM15_03765"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HAT6797389.1"
                     /translation="MSRVIWIVIDSVGIGALPDAEKFGDSKDVSTLGNIFKEYPDIQI
                     PNMRNLGIGNIDGIDFFESIKEPIGCFGKCKEMSQGKDTTTGHWEMTGIIVDKPFKTF
                     EHGFSKEIIEEFEKKTGRKVVGNKPASGTVIIDEYGEHQIKTGDVIVYTSADSVFQIA
                     ANEEVIPLEELYNMCKIAREIMMGDNAVARVIARPFIGKKKGEFVRTSNRRDYSLDPF
                     EPTVLDNIKESGLDVLAVGKIEDIFNGKGITDAIHTKSNMDGVDETLNYMKQDNKGLI
                     YSNLVDFDSKYGHRRDPEGYKKALEEFDSRLPEIMANMREDDILIINADHGNDPTYKG
                     TDHTREYIPVMIYGNKIKKGFNLGVKDTFADIGATVADILNVKLPKHGSSFKEDLF"
     gene            46781..47593
                     /locus_tag="JAM15_03770"
     CDS             46781..47593
                     /locus_tag="JAM15_03770"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HAT6797390.1"
                     /translation="MFEKIAQSSKFINSKSNIKPKIGLILGSGLGDLANDIEDPVTIK
                     YSEIPNFPVSTVAGHAGQLVIGKLEGKEVIAMQGRFHYYEGYSQKEATFPVRVMKELG
                     VEILIVTNAAGGVNKEFKAGDLMLIRDHINFSGSNPLVGKNDDRFGARFPDMSDAYSS
                     KYVDVVKNCAKECNIDVKEGVYMFFSGPNYETPAEVRMAQILGADAVGMSTVPEVIVA
                     SHSNIGVIGISCITNMAAGILNQPLSHEEVIETTQKVKSEFMNLVKTTVKNL"
     gene            47797..49122
                     /locus_tag="JAM15_03775"
     CDS             47797..49122
                     /locus_tag="JAM15_03775"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HAT6797391.1"
                     /translation="MRMYDIIKKKRDNLELSKKEINYFIENYSKGDIPDYQASALLMS
                     IYLNKMNKQETVHLTEAMMNSGDMINLSEVDGIKVDKHSTGGVGDKTTIALIPLVASC
                     GAPVAKMSGRGLGHTGGTIDKLESIPGFSTEMEISKFIDSVNKSKIAVCGQSAKVAIA
                     DKKIYALRDVTATVDNISLISSSVMSKKLASGADAIVLDVKTGDGAFMKTLEESFELA
                     KSMVDIGTGMNRDTIGIVTDMDEPLGFAVGNSLEVIEAIETLKGNGPKDLVELCEVLG
                     AYMLVLSKVAHDFEDGVEKIRESIKSGTAIQKLKEFIENQGGNKDVVDDYSLFKKSKY
                     KYPVKSTKSGYISKIKAEDVGVSAMILGAGRETKDDILDLSAGIILEKKVGDYVNEGE
                     VLAYMYYNDEQKLSLAKGRFIDSYSIVDSKIEKNKLIYGIVTKEEIKKF"
     gene            49335..50414
                     /gene="mltG"
                     /locus_tag="JAM15_03780"
     CDS             49335..50414
                     /gene="mltG"
                     /locus_tag="JAM15_03780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HAT6797392.1"
                     /translation="MNFKENRLKIAVLIIVILIILAGIFVFIQIGPYDKNNKKDVIIE
                     VPSGASVGKISDILYENKLIKNELLFKLLVKVSNKAPSIKSGTYLLNQSYSNNDIISL
                     LVSGKIYQDGIKVTIPEGATSKEIIAMLVSKNLGDKATFENLIKKPQEFYDKFPYLKE
                     DGITSLEGFLYPETYYFNSKKQSEEDILSEMLKVFDSKYTDKFKKKQKELNMTLQEVM
                     EMASIIEKEAVLDKDRPIIASVFYNRLKVGMPLQSDATIQYIFEERKKIVTYDDLKID
                     SPYNSYKNKGLPPTPISNPGIKSIEAALYPEKTDYLYFVAKIDGGNNYSTNYQDHLKY
                     VKEYKEARDKQSKDTKATNKENTKK"
     gene            50586..51260
                     /locus_tag="JAM15_03785"
     CDS             50586..51260
                     /locus_tag="JAM15_03785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HAT6797393.1"
                     /translation="MSNIVNDLVEDYIRVTLKEKEGFLKDLEIYAEENSVPIIHKEVS
                     DLLKVLLKVQKPKRILEVGCAIGYSSIFFATIIGKDADIITVERNEKMIEKAKENIKL
                     AGFDNNITILEGDAEEKLSQVQGEFDLIFIDAAKGQYKLFFDLVIDKLKDGGLLVSDN
                     ILYKGMVAHDDFVVRRKKTIVKRMRNYLDYICNCDYLSTSLVPIGDGVALSYKESKRG
                     DVDGIK"
     gene            51247..52494
                     /locus_tag="JAM15_03790"
     CDS             51247..52494
                     /locus_tag="JAM15_03790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HAT6797394.1"
                     /translation="MELNKVELLAPAGDLERLKIAITYGADAVYIGGEIFGMRSAAKN
                     FSKEDMAEGVAFAHERGKKVFVTVNIIPHNEDFLQLEDYLLELEEIGIDAVIIADPGV
                     LSVIKKVIPNMEIHLSTQANTTNYLSANFWYEHGIKRVVVARELSFDEISEIRAKTPL
                     DMDIEAFMHGAMCISYSGRCLISNYMTGRDANKGSCAQSCRWQYHLVEEKRPGEYFPI
                     YEDERGTFFFNSKDLCMIEYIPELIKSGITSLKIEGRMKTAYYVATVVRAYRMAIDEF
                     YRDPENWKFNPMWMEELKKGSHRHFTSGFYLNKPTTEDQNYQSASYVRNYDFIGIVRE
                     TEDEDGLIVVEQRNKMCVGDEIEVMGPYKETMFTKIEEMYNEEGEAIESAPHPRQIVK
                     LKLSVKVGKDYMLRKVIEEKVEE"
     gene            52566..54230
                     /locus_tag="JAM15_03795"
     CDS             52566..54230
                     /locus_tag="JAM15_03795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HAT6797395.1"
                     /translation="MSKKKTPFLKKVGKRSWCIFTIILIIYSILIYRLVDIQVLKGNK
                     YKQSVESQSVEKVELNSGRGIIYDRNNKKLTDTSKSQVLIVEKEKLNNNYKILELIKK
                     ATKMNDLDIYKAVQEQLTRPIIQIQTKNIDKSMKKELEKNGIMVEEKTMRYAKDGLLS
                     HTIGYIKEDDKSGQSGIEKSMDSVLRNSNEKYISAFKAGDAGNEKSLNILKGSVKTVD
                     NKDKDRHLKTTIDYNIQKKLEQILNKEENPTAAIISEASTGEILAMCSRPNFDQNDIS
                     KSLKGKNGEFENRVIKATYPPGSVFKMVVLFSALENGVIDENYTYNCTGKTKVGNTNE
                     ILRCNKRDGHGFQNLRQAFSNSCNPAFLDIAMKLGKEKILKSAEKLHLFEKVDIGLDE
                     EKIREAPKNISIRNLAIGQENIEFTPLQINQMTQIIANNGTFKPLYLYKSLVDNNMNT
                     IKTYKSSKKEELISPYVCTQVKEYMKSVSRIGTAKDLKDIEGGCGVKTGTAQSSLNKK
                     AIDHGWITGFYPEERPKYVITVLVEGTQKGNKSATPIFKEICESIK"
     gene            complement(54327..54611)
                     /locus_tag="JAM15_03800"
     CDS             complement(54327..54611)
                     /locus_tag="JAM15_03800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005586049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAT6797396.1"
                     /translation="MCNEISLLDILGTEANYVLDEVELKVQVGKLYEQLNKILTPRER
                     EIVQLRYGLTPYGYKTQREIAQKLDISRSYVSRIEKKALKKLEKELVQES"
     gene            complement(54634..56151)
                     /locus_tag="JAM15_03805"
     CDS             complement(54634..56151)
                     /locus_tag="JAM15_03805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAT6797397.1"
                     /translation="MSVAIYLRKSRADEEAEKQGEFETLSRHKSTLLKLAKEQNLDVI
                     EIKEELVSGESIIHRPKMLELLKEVEENKYDAVLVMDLDRLGRGDMKDQGIILETFKE
                     SKTKIITPRKTYDLTDEFDEEYSEFEAFMARKELKLISRRMQRGRIKSVEEGNFIGTS
                     APFGYDAVTTGRKERILVPNKDADVVRTIFDLYINEDMGCSKISKYLNNLGIKTATGA
                     NWYNSAITNIIKNKVYCGYIQWQKKDYKKSKNPNKIKTVKLRPKDEWIEAKGKHEPLI
                     SEITWKKAQNILKKNGHVSYGNQIKNPLAGIVICKNCGRPLVYRPYADHDYIICYHPG
                     CNKSSRFEFIEAAILKSLEDTVKKYQLKSSDLDLDKNNKDSNIEFQKRVLKGLETELK
                     ELGKQKNKLYDLLERGIYDEDTFIERSNNISSRTEEIKDSIKTVKNRLSTVKKDNSKI
                     IEDIKTVLSLYHDSDSLGKNKLLKSVIDKAVYYKSKEQKLDSFELMVHLKLHEDQ"
     gene            complement(56276..57097)
                     /locus_tag="JAM15_03810"
     CDS             complement(56276..57097)
                     /locus_tag="JAM15_03810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAT6797398.1"
                     /translation="MIISKKITAILVSFLIMISMVGCAPKESATEVAKKYLDSIEIKD
                     YEVAYNLLSKDSKESVSLEKFEEYQDTLFKLQTLKDYKLGEENKVEKYKYSNKEYTDL
                     VKIKETDTIKYITENKEDTANFDRYFIIEDNEYKLLWHKDFKRALSSNYVKIARSETK
                     KDEDKDYNKAAIDIKKAIEIDDKNPLAYYTQSYIYIELQRYDEALKSIDKSLEYLDKN
                     NEAYKIDASDAYNLRGVIFMSKSEFNKARESYNKALELNPDNEYAKTNLNDIKGL"
     gene            57288..58715
                     /locus_tag="JAM15_03815"
     CDS             57288..58715
                     /locus_tag="JAM15_03815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp26"
                     /protein_id="HAT6797399.1"
                     /translation="MKIKKLLTIGLSLSIFIASCPISANALDKIESIKGADKYETAGI
                     IADKQNYTTAILINADSTMADGLSASGLAGAINAPILLTKKNNIPNATLKRLEKAKKV
                     YIIGGENSINKYTETVLKGKGIEIKRLQGSDRIKTSYNVAKEINSINKVNKVILTNAF
                     KGEPDAMSAAPVAVRDKAAIVLTDGKSVPFNTTGVESYVIGGTSSMNDKLVKYTNSTR
                     LGGTDRYDTNKKIINKFYSEVKEFYIASGTDLVYALVGSTVAKNNAIVLVDNDSNKSV
                     LKSTTKLTAIGNLSDSILQQCLNVTKNIGDSNTGREYTVEDAANAVKKLLDVKKFYYE
                     PNYSEAEDLIFLLDKNFDFSGKEYYVFAYIKQGAEGDVRYCVAKNDMSKVYTYDVNGN
                     MKVCNPDDYKNKGSITEEQAKQIALKECAKRHKVSINNLVVDMIDFRDDIYSGNVYAV
                     KINSKNSNGTFGWFFIDIETGKIYN"
     repeat_region   59671..60362
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=59738..59766
                     /rpt_unit_seq="gttttatattaactaagtggtatgtaaag"
     gene            complement(60649..60873)
                     /locus_tag="JAM15_03820"
     CDS             complement(60649..60873)
                     /locus_tag="JAM15_03820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6797400.1"
                     /translation="MDVNQRIKYTRENMNCSQKELLEKTNINTSVMNRIESGERPTRD
                     DGLIIFAKIFGLYTDYILGLSDTEKLNIGN"
     gene            62016..62234
                     /locus_tag="JAM15_03825"
     CDS             62016..62234
                     /locus_tag="JAM15_03825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797401.1"
                     /translation="MKILQQFKPYKYDKEKNIEYDEKIIANQNTEVYIVYPRISDEEN
                     RRRWEEFNEVAKEVAINIAMKKVETVES"
     gene            62876..63085
                     /locus_tag="JAM15_03830"
     CDS             62876..63085
                     /locus_tag="JAM15_03830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797402.1"
                     /translation="MMGLKLKRRYKNVLIYINIRTIIHINCKIKFIELYLTFNELKNE
                     LANNEKTTVINENNKVFSGLVDFSN"
     gene            complement(63454..63837)
                     /locus_tag="JAM15_03835"
     CDS             complement(63454..63837)
                     /locus_tag="JAM15_03835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797403.1"
                     /translation="MRKKFFIGILIVLIISVIAILNIKNDKNVFIGESENWKAKFVTT
                     EGHSKLEIKYKNSKDVVEQKFNYSYQFIDGEDAVVVVKNEILEAGQEKAIKIQRPGLY
                     SNRESSYKLIISWNGNEETINLKKK"
     gene            63964..64290
                     /locus_tag="JAM15_03840"
                     /pseudo
     CDS             63964..64290
                     /locus_tag="JAM15_03840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433383.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            64492..64707
                     /locus_tag="JAM15_03845"
     CDS             64492..64707
                     /locus_tag="JAM15_03845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797404.1"
                     /translation="MHINQTGFISNGLGIKQQQKKEPTSNSFSYNAPSSWKPVGRDSV
                     QYNCGFELIATLVRGGSSWAFNFIVQP"
     gene            complement(65693..66010)
                     /locus_tag="JAM15_03850"
     CDS             complement(65693..66010)
                     /locus_tag="JAM15_03850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797405.1"
                     /translation="MNFRNIYLILMGLGIIILTTIISLIEIKIGFCNEKYFNKLESKY
                     GNIDRKRTIKLEVLYRYVTGFEYIAIGLFTKRLDITIIAIILVATITVILYYLIRKRY
                     ITI"
BASE COUNT        26656 a         6946 c        11757 g        21317 t
ORIGIN      
        1 ttaaaaaacg taaaaaaatt tataaaaatg tagaaatgtt acctacataa aaaactggtt
       61 aaatgttatt aaaataactt tattagctct ttatattata ttattataac aaatgggaaa
      121 gaataatcta cattaagtta acttgttaat atattattag tgaaatacac aatttaccat
      181 actagaaata tgatataata taaaaaaaaa gtatatactt ttatattaaa aggtgatata
      241 ttatttatga aaatcgttta atgtatacaa taatatatct ataacaaaat aataaaagat
      301 agagttttat ttagacattt attacaaatc aaaatttatt acataattat ttataaaaaa
      361 atctaaggag gaaataataa tgaaaatatt agtattaaac tgtgggagtt cttcattaaa
      421 atatcaatta atagatatga ataatgaaga agttttatgt ataggattgg ttgaaagaat
      481 aggaatagaa ggttctatat taaaacatga aaaagcaggt agagatgata aatacgttgt
      541 tgaacaacca atgaaggacc acaaagatgc aatagcatta gttttagaag ctgttgctca
      601 tccagaattt ggtgcagtta aagaaatgaa agaaatagat gcagtaggac atagagttgt
      661 acatgctgga gaaaaatttg caacttcagt agtaataact ccagaagtag aagaagcttt
      721 aaaagaatgt atagatttag ctccacttca taatccagca aacataatgg gaatagatgc
      781 ttgtaaagct atacttccag atgtaccaat ggtaggtgta tttgatactg ctttccatca
      841 aacaatgcct aaatcttcat acttatatgg tttacctcat gagctatata ctaaatatgg
      901 ggtaagaaga tatggattcc acggaacttc tcataattat gtatctcaga gagcagcaga
      961 gatattagga aaagatataa aagatttaaa aatagtaact tgtcacttag gaaatggtgc
     1021 ttctatagct gctgttgatg gtggaaaatg tgtagataca tctatgggat tcactccatt
     1081 agaaggatta ataatgggaa ctagatgtgg agatatagac ccagctatat taccattctt
     1141 aatgagaaaa gaaggtttag atgctgatgg attggataaa ttaatgaata aagaatctgg
     1201 agtatatgga atgactggaa tttctagtga cttcagagat atagaagatg cagctaaaaa
     1261 tggagacgaa agagctcagg ctacattaga agcgtatgtt aaaaaagtac aaaaatatat
     1321 aggcgcttat gctgctgaaa tgaatggatt ggatgttgta gtatttactg caggcgttgg
     1381 tgaaaatgga aaggctataa gagcagatat tgcttctaac atggagtttt taggaatgaa
     1441 attagataaa gaagctaatg atgttagagg aaaagaaaca gtaatatcta ctgctgattc
     1501 taaagtaaaa atgcttttaa taccaactaa tgaagaatta atgatagcta gagatacatt
     1561 aagattggta aaataattaa attaaaccta tgcctatcaa gtaaaaatac ttgacaaaca
     1621 aatgctagat ttgtataata aatttggtga tatgttgagg tgaacttaat gaaagttagc
     1681 atagaaaaaa taaatagaaa agaaactgac aaaatagact tgaatttttg tgaaaaaatt
     1741 gatactatta gttattgtga tgagatttac aaattagtat cacctgtaaa tttaaaaggg
     1801 aaagtgtcaa agactaataa aggtttgtat ctagatatag atgtcaattt tacaattgtt
     1861 gacaattgtt caagatgtct taaagaagta gaaataccac tagagtattc tatacaaggt
     1921 tttttagtaa aagaagaaga ttatgatgaa gatgagtttg aggaatttga tccttttata
     1981 ttcgatggtg aagaaatcga ccttattgat ataatagaac agacattaga ttttaatgta
     2041 cctcataaag ttctttgtag tgaaaactgt aaaggtcttt gtcaagtatg cggggcaaac
     2101 ttaaatgaag aagagtgttc ttgcagtgaa attacaaacg atgaggaata catagatcct
     2161 cgttttgcta aattaaaaga tttatttaat taaattttga ctaaggaggt ggcgtaaatg
     2221 gcagtaccaa agcgtaaaac gtctaaatca aacacaaaaa tgagaagagc agctaactca
     2281 aagatggaag caacaggatt tgtaagttgc ccacaatgtc atgagccaaa attaccacat
     2341 agagtgtgtc cagactgtgg atattataaa ggtaaagaag ttgtgtctaa gtaatagctt
     2401 ctaaaaagca tgtagagtat actctacatg ttttttttgt acatataaaa aaataagatg
     2461 atttactaga gaaaataagt ggattttatg catattaaaa aatagaaaaa taataatata
     2521 agtattgaaa atttttgtgt gttactatat actactatta gtagctggta ctaattacag
     2581 ctataaaatt tggagggaac atgaaaaaga aaagtaaagc ccaaagacaa aaagagctta
     2641 tagatatgct aaagacagat cctttttata ctgatgaaga attatcaagt ctgtttgatg
     2701 taagtataca gaccataaga ttagatagaa tgagtctaaa cataccagag ctaagagaaa
     2761 gagtcaaatc aatagcagaa actcagagtt caaaagtaaa gactttagga gtaaaggaaa
     2821 ttacaggaga aatcattgat ttatctgtag ggcgattagg tatatctatg ttagaagtta
     2881 cacaggacat gatttactct aagactaata ctttaaaaga tacgtatatt ttttctctag
     2941 cagattcatt ggcaatggct ataatagatg cacctaaggt tattatgaga gttgcaaatg
     3001 taaaaagttt taagttgata gaacaacaag atagacttat agcaaaagca gaagtgtata
     3061 gaaatataga taaaaagcat tatgtaaaag ttgttatcaa caataaagcc caagagcaaa
     3121 tatttagagg aaagtttatc tttgaagaat tagattagga gggaaattat gaaaatagta
     3181 attgatggaa tgggtggaga taatgcacct aaatctaatg tagaaggcgc agtaaatgct
     3241 ataaaagaat atcaggttga tttaataatc acaggagata aagatttact tgaaaaggaa
     3301 ttttcaaatt atgaatttga tagaaataaa ttagagatag ttcatactac tgagattata
     3361 gaaaacgaag ataaaccagt aaaggctata agaagtaaaa aagattcatc tatggtagta
     3421 gcattaaatc ttgtaaaaga aggaaaggca gatgctataa tatcagctgg aaatacagga
     3481 gccttacttg ctggtggatt atttgttgtt ggtagaataa aaggaatcga tagaccttgc
     3541 ttatgttcag caataccaaa tgtaaagcga ggaatgacac ttatagcaga ctgtggcgca
     3601 aatgcagatt gtaaacctaa gaatctagtt gaatttgcag ctatgagtaa tatttattca
     3661 agaaaagttt taggtcttga aaatcctaag gtagcattag caaatgttgg actagaagaa
     3721 ggcaaaggca atgatttagt caaaaggtca tatgaagaaa ttaaaaaatt agatttaaat
     3781 tttataggga atgtagaagc tagagaagtt ataaatgcat acacagatat aatcatatgt
     3841 gatggattta caggtaatat attacttaaa tctgctgaag gtgtagcact ttcagttatg
     3901 agtcttataa aggaaacttt tatggccagt acaaaaagta aaataggagc attacttata
     3961 aaggatgatt taagaaaatt aaaaagtttt atagattatt ctgagtatgg gggagctcca
     4021 cttttaggtc taaatggagg agttataaaa gctcatggta gttctgatgc taaagctata
     4081 aaaaatgcta taaatcaagg aataaaattt tcaaagggaa aagtcgttga agatattaac
     4141 caatttataa gcaaatacaa tgaagaaaat aaaaataacg aagatgaata aactcgtttt
     4201 ggaggtttaa tatataatga atacaaaggc tggaatatta ggagtaggaa gttatctacc
     4261 tgagcaatca tatgataatt ttcacttcga aaaaataatg gatacatcag atgagtggat
     4321 aagtactaga actggtatta aggaaagaag atttgccaaa gagtctgaag caacttctga
     4381 cttagcatct aaagctgcct taaaagctat agaatgtgca aagttaaacg tagaggatat
     4441 agagctgatt atattagcta caattactcc tgatatgtct ttgccttcaa ctgcatgtat
     4501 agtacaagat gcaataggag cagtgaatgc tactgcattt gatatatcag cagcttgttc
     4561 tggatttgta tatggagtaa ctattgcaaa gcaatttgtg gaaacaggtt gctataaaaa
     4621 tgtgcttgta ataggagcag aaacttgttc taagttttta aattatgatg atagaacaac
     4681 agcagtattg tttggagatg gagctggagc agctgttatt ggtcctgtaa atgagggtgg
     4741 aatactgtct acacatatgg gctctgatgg taaaggaaaa gattgtttaa aagtacctgc
     4801 tggaggttca agacttaagg caagtaaaga gactgtagaa gctaatctac atacaataga
     4861 aatggcaggt agtgatgtgt ttaaatttgc agttagaaag atggcagaaa cttctttaag
     4921 agctcttgaa aaagcaaatc taaatacaac tgatatagac tacttagtgc cacatcaagc
     4981 taatataaga atcatacaag cttcttctaa gagattagag cttgatatga aaaaagttta
     5041 tgtaaatata gacaaatatg gaaatatgtc tgctgcatct ataccagtag cattagatga
     5101 agcttataga gaaggtaaaa ttaaaaaggg tgataatgta gttttagttg gctttggtgg
     5161 aggtctaact tggggggctt cagttgtcaa gtggacttta tagtataaaa tatctaaaat
     5221 gatttaatta acaaaattaa acttatacac aaaataaagt tgattaataa taaaaagttt
     5281 acttttatga tttcaagtga aggagaattg tatgaataaa atttgcaaaa tattaaatat
     5341 aaaataccca gttatccaag ggggaatggc atgggtagct actgcatcat tagcaagtgc
     5401 tgtatctaat gcaggaggac ttggcataat agcagcagga aacgcaccaa aagaagctat
     5461 aaagaaagaa attgttgagt gtaaaaaatt aacagataaa ccttttggag taaatgtaat
     5521 gcttatgtcg ccatttgttg atgatataat tgatttgatt atagaagaaa aagttcaagt
     5581 tattactact ggtgctggaa atcctgcaaa gtatatggat agattaaagg aagctggaac
     5641 aaaggttatt cctgtagtac ctacaatagc tttggcacaa agaatggaaa agttaggagc
     5701 tacagcagta atagcagaag gtactgaagg tggaggacat ataggagaac ttactactat
     5761 ggtcttagtt ccacaagttg ctgatgctgt aaacatacct gtaatagctg ctggaggaat
     5821 tgtagatggt agaggaattg cagcatcatt tgcattaggt gccagtgcag ttcaagtagg
     5881 aactagattt atttgcagtg aagagtgttc tgtgcattca aactataaaa acttagtact
     5941 aaaagcaaaa gatagagatg caattgtaac aggaagaagt actggtcatc cagtaagaac
     6001 attaaaaaat aaactatcaa aagaattttt aaagatggaa caaaatggag ctactcctga
     6061 agaattggat aaaaaaggta caggagcttt aagatttgca acagtagatg gagacataga
     6121 aaaaggttca tttatggcag gtcaaagtgc tgctatggta aaagaaataa caccttgtaa
     6181 ggaaattata gaggctatgg taaatcaagc aagagagatt atgccagcaa tagaactgta
     6241 aatcaggagg agcaagatgg gaaaagttgc actagtattc cctggtcaag gagctcaata
     6301 tgtaggtatg gccaaggatt tatatgaaaa taatgctgtt gctaaaagtg taatagatga
     6361 ggctagtgat gccttaaata tggatttaaa aaaccttatg tttaatggaa atgaagaaga
     6421 actttctaaa actgaaaaca ctcaacctgc tatggttaca catagtgtag cagtattaaa
     6481 agcggtacaa gctcaaatag atttaaaata taatgcatgc ttaggattat ccttaggaga
     6541 gtatagtgcg ttggttgcag cagatgcaat tgactttaaa gatgctgtat gtttagttaa
     6601 aaaaagaggt aagtttatgc aggaaacagt tccagcaggt gttggagcta tggcagcaat
     6661 tttaggttta gatagaaatg tacttgaaaa tgtggttaaa gatatacaag gaggtattgt
     6721 agaagtagca aattacaatt ctcctggaca aatagttata tctggtgaaa atgaaaagat
     6781 agaagaagca atggtaaaat gcaaagaagc aggagcaaaa agggcagtta aattaaatgt
     6841 aagtggacct tttcactcat caatgttaaa agaagctggt gtaaaattgg ccagtgaatt
     6901 agaaaaagtt aacataacta aacctaaagt tgatgtggtg gcaaatgtaa atgcagatta
     6961 ctataaaaac gaaggtaaag acctgcttat aaaacaagta agttcatctg ttctttggga
     7021 agattctata gaaagacttt taaatgatgg atatgatact tttatagaaa tgggacctgg
     7081 aaaaacttta aaagcattta ttaagaagat agcttccaat aaaaaagcaa atgtcaatat
     7141 ttataatata gatggtatag attctcttaa tgaatttgta caaaattata gaaatggaga
     7201 gatataatga taaatcttac aggacaagta gcagttgtta ctggtggctc taggggtata
     7261 ggaaaagaaa tagcaaaaaa actagcatct tttggagctg atgtagtaat caattatact
     7321 tctaaagaag atgaagcact aaaaactaaa aatgaaatag aaagtatggg ggtaaagtgt
     7381 acctctataa aatgtgatgt gtctaaattt gatgaagtga atcaaatgat agattctgtt
     7441 gtaagcgaat ttggaaaaat tgatatattg gttaataatg caggcataac taaagatggt
     7501 ctgcttatga gaatgaaaga agaagatttt gatagagtta tagatataaa cttaaaaggt
     7561 gtctttaatt gtacaaaagc agttactaaa cctatgatga aaaagaagta tggaagaata
     7621 ataaatatga cttcagtagt tggaattatg ggtaatgcag ggcaaactaa ttattgtgca
     7681 tcaaaagcag gtgtaattgg atttacaaaa gcttctgcaa gagagttagc atcaagaaac
     7741 ataaatataa atgcagtagc acctggattt atagaaacag atatgactag agtactaagt
     7801 gatgatgtaa aagaatcaac actagcaaac ataccaaaga aatcttatgg taaaccagaa
     7861 gatgtagcca atgccgtagc atttttagtt agtgacatgt caagttatat aacaggacaa
     7921 gtaataaatg tagatggtgg aatggtaatg caataataat ttaaaaagta gagaaatcta
     7981 ttaaaataaa aaattttagg aggtacacaa tgtttaataa agttgtagaa ataataatag
     8041 agcaattagg agtagaagat aaagaaataa ctatggagac atcattaatg aaggatttag
     8101 aagcagattc attagatgca gtagaaataa taatggcact tgaagatgaa tttggtatag
     8161 aaataccaga tacagaagca gaaaacttca aatctatagg agatatagtt aagtatatag
     8221 aagctaataa atagtcgagc tttaaaaaag tggaggtatc cgatgaataa aagagtagta
     8281 ataacaggac ttggatgtgt tacgccgttg ggaacgggaa aagaagagtt ctggagtaat
     8341 ataaaatctg gagtatctgg tatagataaa ataactaatt ttgatgctag cacatatcaa
     8401 actcagatag caggagaagt taagaatttt catccagaag aatatataag taaaaaagaa
     8461 ttgaagagat tagataaatt tgctcaattt gcaatagtat ctgctaaatt agcagttgaa
     8521 gatgcaaatc ttgatttaga taaagttgat agagaacgtt ttggtgttat aataggttct
     8581 ggaataggtg gagttgaagc tatagaaact caacataaaa ttcttttgga aaaaggaaat
     8641 aaaagagtaa gttcactttt tgtacctatg atgataggaa atatggcagc tggtcaagtt
     8701 tcaatatttt taggagcaaa agggcctaac actaatgtat gtacagcttg tgcatcagga
     8761 actcattcaa taggtgatgc ttttaaggta attcaaagag gtgatgcaga catcatggta
     8821 gcagggggct ctgaagctgc tgtaacaggt cttgcttttg ctggattctg taacatgaag
     8881 gctatgtcaa ctagaaatga tgaccctaaa actgcatcaa gaccgtttga taaagacaga
     8941 gatggttttg taatgggaga aggagcaggt attgttatct tagaagactt agaacatgct
     9001 ttagcaagag gggctaaaat atatgcagaa gtagttggat atggtttaac tgctgatgca
     9061 taccatatga caactccagc tgaaaatgga gagggagcag ctaggtctat gaatatggct
     9121 ttgaaagatg gaaatgttcc attagaagaa gtagattata taaatgctca tggaacttca
     9181 acttattaca atgatttata tgaaactatg gctataaaaa ctgtatttgg agaaaaggca
     9241 tatgacttat gtgtgtcatc aacaaaatct atgactggtc acttattagg agcatcaggt
     9301 gctatagagg ctgttgtttg tgctatgagt atagaagata gttttgtgcc tccaactata
     9361 aacatacaag aagttggtga agatttggat ttagattatg ttccaaatca aggtaaagaa
     9421 aaaaatatta gatatgcact atcaaattct ttaggatttg gtgggcataa tgctacaata
     9481 gtactaaaaa aatatgtata aataaatatt aaatataaaa ctaaaaaaca agcacttgtt
     9541 ttaactgtat aaatttatat tagcttaaat ttaaagtttc ctaaattatt ttaggagact
     9601 tttttattaa gatttaagtc tagcatatgt tgtaaatcat tttgatatat tgtattatta
     9661 attattaaga ggttatttat atatgcaagt tttcattcta caatatacaa aaggaggact
     9721 aaaattttga attttagact accaaagaaa aggttaccca aaaagataat ttttatatgt
     9781 ataatactta ttagtattat tttgtttata aagtatgacc aaaatggatt gaaagaaaga
     9841 gaaattataa ataagggaaa atatatgtct gaaagccttg tggcagataa ggagtatgat
     9901 gaagcaaaaa aagtggttaa gacttctttc gaatctattc cagaaaaaaa atacaataaa
     9961 gtatataatg aagtttggga tatgttaaag actatttcat atgttccaga tggaacgaag
    10021 atagtcatta attctttaga aaagatgaga gaatcagatg tgaaattatc tgatgaatgt
    10081 agatttaata tagaaaaaag attagcatca gtgtatataa tggataataa ttattctaag
    10141 gcagtagatt taactgtaaa gtctataaaa ttggctgaga aattggggaa taattatgaa
    10201 aaagcaagac tagatgttga tttggcgagc atatttttaa agataggtag ctatgaaaca
    10261 ggagagaaat taataaagga ttcttttaaa atagatattg atgaaggtga aaaaaatgga
    10321 atggttagat tatatgctat tataaatcta gcagaaatat atgtagaaga gggagaatat
    10381 gataaagcta ttgaaataag tagcaggata aaagattata aaaagtttgt aaatacggat
    10441 aattacaatg attttgatat aatggcctct ataatgaagt caaatgcgta tgtgggcaaa
    10501 aataatatac aaaaggcaaa gactttttta gaaaaagctg attatcttat aaaatcagat
    10561 agaacagttt atatattaga taaagatatg tactattata tggcaatggg aaacttagaa
    10621 tataaaagcg aaaattataa ttctgcaata gataattata aaaaaagttt agagatatct
    10681 accaaaagaa agttaactca ggagaaaata aaaaatttaa ataagatatt aaatatatat
    10741 gaaaaacaag gaaatataga atctttaaat gagtatcaaa agatgttaat aaatgaatat
    10801 aaagagaaca aaagtataag agattcagag actagtttct atataattga taaagtatca
    10861 aacgaaagta agctatttga aaaaactaaa aaagaaataa aatattataa aatattattt
    10921 acagtaattt taattgctat attagggtct acttttttat acaaccgatt gaagtatttt
    10981 aaagcacaaa atttacatga tggtcttaca aatgtttata atagaaaaag ttttgatatt
    11041 atgtatgaaa agtacagaga gaaagatgat aattttgcac ttgtgatgat agatattgat
    11101 aatttcaagc tcataaatga taattatgga cataaatttg gtgacactgt tataaaggga
    11161 ataacaaata ccatttgtgt tatgttagaa caagatgata aagtctttag gtacggagga
    11221 gaagaatttt ctgtattaat aagaaataaa tctggtgagg aagtagcaga tataattgac
    11281 aatataaggg ttgcaattgc aaataaaaag tggaatgatg atgtgactgt gactataagt
    11341 gcaggtgtat ctcatatttc agatagcaaa gatgtactag aagaagctga taaaaattta
    11401 tataaagcaa aacaacttgg tagaaataaa gtagtatata agtaattata tactatataa
    11461 ataagaggta taaatatgaa acaatcaata gctatagtaa ctgataaaat aactaaacta
    11521 tcatctttct tagaagaaaa tatacgtttg gttttaggta attatattga tataaaccac
    11581 tattatctgg aagttttaaa agagaatgat aaaatacaag gtgattttgt actagtaatg
    11641 aatgatgata gattaaacag tatgagaaag catttagtac aagatagtaa gattatagtg
    11701 ataaggagaa cacttaaaga aaatgaaata tatggattat tttcaatacc aaatggaact
    11761 gaagtattgg ttgtaaatga tacaaaagaa actaccttag aaacgataag cttattttac
    11821 aaaataggag taaaaaattt aaagtttact ccatatatta aaggaaaaat ttataaaaat
    11881 atagacatag ctataacgcc tggagtaaag gaaaaagtac caagttatat aaataaagta
    11941 atcgaccttg gtaatagata tattgatata tctactttta tagaaataat aaatggtctt
    12001 agaattgatg ttaaagaaat acgtaaaaat ttaatggcat attctgagag tttaataagt
    12061 ttagataatg gagttaaaga taattatagg caactgtttt taaaaataga agaacaagat
    12121 gttatattga atctatcaaa agatggaata atatttactt cagcagatgg tataataaac
    12181 acatttaata aagaagcttt aaaaatttta ggtataaatg aaaatccaca aggcaaaaac
    12241 atagaagata tcatttctga agatttaaat attttacttg aagacaaaga aataattgat
    12301 gaagtggtat ttacaaataa aaaatatata aatgtaaata aaaaaagtat tttttctatg
    12361 gggaataaag ctgggatata ttataattta caagaaataa cgtatataaa aaaattagaa
    12421 caaaatctta ccaataaatt aagagaacaa ggtcagatag caagatatac atttaaagat
    12481 ataaaaacta aaaataaaaa tatggtaaag tgtgtagaat tggctaaaaa aatatctaaa
    12541 tcagaccttt ctgtattaat aataggagaa agtggtactg gtaaagaatt attatcacaa
    12601 tcaattcata atgcttccaa tagaagtaat caaccattta tagcggttaa ttgtgcagca
    12661 gttccagata gtctattaga aagtcaactg tttggatatg aaaaaggctc ttttacagga
    12721 gctttaagag aaggaaaaaa gggtctattt gaacttgcta ataatggaac tatatttctg
    12781 gatgaaattg gagatatgcc tccattgcta cagacaaagt tactaagggt attacaagaa
    12841 aagcaggtta tgcctatagg ttcccataat gttataaaca tagatgttag ggtcatagca
    12901 gcaacaaaca aaaacttacc aaagatgatt agagaaggaa aatttagaga ggacctgtat
    12961 tatagactaa atgtattgcc aatagatgta ccatcattga ggaatagaaa agaagatata
    13021 ataacactta tgaatttctt tttgaaaaac aatataagac tttcgccaga agttataact
    13081 attttagaaa aatataattg gccaggaaat ataagagagt tacaaaatgt tgcttcttat
    13141 gtaagtctaa tgtgtgatag tatggttttt agagatgact taccaccata tataaggata
    13201 gaatgtgcta acaattatga agatggattt ggttatacaa aaaaagaatt tgaggaaata
    13261 ctgaggattc tatatgaaag aagagagtca tcctctggag ttggaagagg gtttataatc
    13321 gaaaagctta tacaggaagg gattgagatt tctgaaagca aagttagaaa ggtgctatct
    13381 tatttaagtg aatgtggata tatatcatct aaatctggta gaggaggaag tcaaataacc
    13441 tcagagggga taaaacttta taataatata aattaagcta agtatttgat attaaaatca
    13501 catattttga atttagatat ttaaataata aacttttata tttatagaga ttaatttata
    13561 ctatgtcaga aagaatattg taatttataa ttaaatatta ataggttttt aaaataggat
    13621 tagataggta ataggttaag ttagaataac ccattaccta tttttatttg taagaaaagt
    13681 gtacatagag ttaaaagtaa aaaatacaac taataaaact attgaaaaca ctagataaat
    13741 aataaataaa aataattata aattttggca tatatattgc taatcataga gataagacga
    13801 caaaataatt gggaggttta atgatgaaat acaaaacaac agggacttgt gctacagaaa
    13861 ttgaatttga agtaaaagaa aataaagtta taaatgtaaa ctttataggt ggatgtgatg
    13921 gaaatttaaa agggctaaaa gtattagttg aaggtatgaa tatagaagat gtaatacaaa
    13981 agttaaaggg aatagagtgt aaaacaaagc aaacatcttg tccagaccaa ctgtctctag
    14041 cattggaaaa ttatatgaat ataaaataat acataaaaca atcgattagt taggagctta
    14101 attatgaaac caataatagg gattttagga aatttgataa taatggaaaa tggtatgttt
    14161 ccaggtcttg aaaggtcata tgtaaataat gattatataa atgcagtact aaaaggtgga
    14221 ggtagtccag taataattcc tgtaaataca gataaagaag ttataaaaaa acagattgaa
    14281 atggttgatg gagtcttaat atctggagga tgggatgtca atcctcaact gtatggagaa
    14341 gaaacaagag aagaaacgac atttatatat ccagaagtgg atgaatttga tttaattgca
    14401 ataagtatag cattagagct taaaaagcct atattaggtg tatgtagggg actgcaaatt
    14461 ttaaatgtaa gtttaggagg aactttatat caagataata atctgataga aggaagttat
    14521 ataaaacata cacaatcttc taaaagacat gtagctactc ataaagttga tgttaaagaa
    14581 ggaagtattt tagagggaat tttaggaaaa caattactta caaatagtta tcatcatcaa
    14641 agtgtcaatc agcttggaaa aggattaaaa gccatagcat actcaaaaga tggtataata
    14701 gaagctattg agaaagagga tgaaaatttt gtagtaggaa tacagtggca tccagaaatg
    14761 atggtagatt actgtgataa aatggaaaaa ctatttaaat attttataaa tatttgttca
    14821 aatttataat ataccttggg gggattgaac atgaacgaaa agaacaaaat gggattaata
    14881 agtattatac ttttaggtat taatgcagta gtaggagctg gagtttttct attaccagga
    14941 gatgcaatga aatcatttgg tgtagcaagt atatttgtat atatatttga tatgttgtta
    15001 gttttatcta tggcattctg ttttgctgaa gttgcaggta aattcaataa aaatggcgct
    15061 gcatatgtat ataccaaaga agcttttgga gatttttgtg gttttgaagt aggtcttatg
    15121 aaatgggtaa taggatgtat ttcttgggga gctttaatag taggttttcc tacatcatta
    15181 tcagcagtat gggctccagc aggtgaacca catatacaaa aaattataat tgtagtcatg
    15241 atagttgggc ttacaattat aaacttatta ggtgtatctc tatcaaaaat tgtacaaaat
    15301 gttataactg taggtaaact aattccatta atactattta taggaatagg tatatttttt
    15361 ataaaaggag ttaattttac ttcttcaaca atggtacctc caggagctgg agcaacagag
    15421 tttggagcag cagcactttt aatgttttat tcatttacag gatttgaatc tatagcagtt
    15481 gcagcagaag atatggaaaa tccacaaaaa aatataccaa tagcaattat aagtgtaata
    15541 gtaattgcat caataatata tatattaaat caagttgtat gtgttggtat actaggagat
    15601 tcgttatcta gtacatctac accagtggca gatgctgcaa gaatatgctt tggaaatatg
    15661 ggagctggat tggttacctt tggaacattg gtttctgttg gtggaatttg tatgtgtggt
    15721 gcttttgtaa atccaagaag ttgtgtagct ttagctgatg ataaaatgtt accaagaata
    15781 tttgcaagaa aagataaaaa aggtacacca tatgtagcga taatagctac tatgttaatc
    15841 actataccaa tagctctatc tggaagtttt gctgaattag cagcaataag tgcagttgct
    15901 agattcatac aatacatacc aacatcttta tccgtattag tgtttagaaa gaaaagacca
    15961 gaattagtag gtacttttaa aactcctttt ggagcagtga ttcctctaat tgctgtatgt
    16021 gttggaacat ggttgttatt ccaagcatct atgcatcaat taattatggg attaggagct
    16081 ttggcaattg gagtaccatt atactttata atgaagtctt ataatagaaa agtctatggt
    16141 gaaaatttaa agaaaatagt ttaattatgt tataacaatt tattgagtta aaattagaca
    16201 ttggcagaaa attaaataca aataagtatc tataaggcta tattaaaata ttattaattt
    16261 tttattttaa tatagcctta tattgttatc aataaatgaa aaatattgta acaacagaag
    16321 aacaatagta ttatgtttat agataaaaaa cttattagga ggtaaattta tgccaacaat
    16381 aacattaaaa aatggtgtag acgtacttat tagagaaggt gtaagagaag atgctcaaag
    16441 cattatagat ttttataatg aagtgggtgg agaaactcat tttctgtcat ttggaaagga
    16501 tgaatataaa atatctttgg aggaacaaga aaatgctata gaatcagcaa aagcatctga
    16561 taattctgtt aaactgattg catttataga tgatgaaata gttgggattg caacgattga
    16621 ttctaatcaa aaagcaaaag gaaagcatgt tggagtatta ggaattgttg taaaagaaaa
    16681 atattgggga attggattgg gtaaaaggct tatgttagac cttatagaat ggtgtaaatc
    16741 aaatggaata accaagaaga taactcttgt cactaatgaa gaaaattata atgctatagg
    16801 attatacaaa aaagttggat ttgaagtaga aagcatacta aagaaagaat gttattataa
    16861 tggtgtttat actgatttaa taggaatgtc acttttattg ggaatataat tagtgtacat
    16921 tttatctcga aaaaagtata ttaagtatgg tataattaaa aaagaatata acttaatata
    16981 attttggagg acgaattatg aaaaatctgt gtaaaatatc agatgattat ttaaacagca
    17041 agcttaagta tttaaagtta ttatcaaaac aatatccaag tatatcaaaa gcaagtacag
    17101 aaataataaa tttagaggct atattaaatc ttccaaaggg aacagagcat tttataacag
    17161 atgtacatgg tgaatatgaa ccatttgtac atgtattaaa aaatggttct ggtgtaataa
    17221 agagaaaaat agaagaattg ttttcaaata caataagaga cagcgaaaaa aaaatgttag
    17281 caactcttgt atattatcct gaacaaaagt tagacctaat aattaaacaa gaggaaaata
    17341 tagatgattt ttatagaata aatatttata gacttataga actttgtaaa tatgcttcta
    17401 gcaaatatac taggtctaaa gttagaaaac tgttaccaga aaattttaaa tacataatag
    17461 aagaactttt gcatgagcat gttaaaagtg aacataaaga agagtattat aaaagtatag
    17521 ttgaaacaat agttgacata ggaatagcta aggagtttat aattgctatt tctacagtta
    17581 tacaaaaatt ggttgtagat agacttcatg taataggaga tatttatgat agaggtccaa
    17641 gaccagatat aattgtcgat aagcttattg aacatcattg tgtagatatt caatggggaa
    17701 atcatgatat attgtggatg ggtgcagcct caggtgaaaa aacttgtata gcaaatgcac
    17761 tgaggatatc agctagatat gcgaatttag acattgtaga agacatatat ggaataaatc
    17821 tgttgccttt agccactttt gctatagaaa tgtataaaga tgacccttgt aaagaattta
    17881 ttccaaaggt taatgaccaa agtgtaacaa caacagaaaa gtctttaatg gcaaaaatgc
    17941 acaaagcaat aagtataatt caatttaagc ttgaaggtga ggttataaga cgaagacctg
    18001 aatttgaaat ggaacataga cttttgctta atatgataaa ctatgatgaa ggtacgatta
    18061 ctttaaaagg taaaacatat aaattaaaag atacttattt acctacaata gacaaaaaag
    18121 acccatataa attaactatg gaagaaagaa atgttattga taaattagta tcttcattta
    18181 gaggtagtga aaaattacaa aaacatgttt catttttgtt ttctaaagga agtatatatt
    18241 taaaggctaa ctcaaattta ctgattcatg gatgtgtacc attaaatgaa gatggaagct
    18301 ttatgtctat gaatataatg ggaaaagagt ataaaggtaa ggctcttatg gataagatgg
    18361 agtctctagc aagagaagga tttttcttta aagataaggc agaagaaaaa ctatatggta
    18421 tggatattat gtggtattta tggactggga aatgttcatc attatttggt aaagatgata
    18481 tgactacatt tgaaagatac tttatagaag aaaaagagac tcataaagaa aataagaatc
    18541 catattttaa acttagagaa aatgagatgg cttgtaaaag attatttgaa gagtttgatt
    18601 tagagcttga tgaatcccat ataataaatg gtcatgttcc tgtggagagt aaaaatggag
    18661 agagcccaat aaaagctaat ggtaaaattc tcgttataga tggtggtttt tctagggctt
    18721 accaaaaaac tactggtata gctggataca ctttgatata caattctaga actttgcaat
    18781 tagtatcgca tgaaccattt aattctgctg aagaagccat tgcaaatgaa agtgatatct
    18841 tatcgacaac tgttgtagta gagcataagg caaagagaaa aatggtgaga gatactgatg
    18901 aaggagtaaa aatacaagag gaaatagaag atttaaaact acttttaatg gcttataaga
    18961 aagggctaat aaaagaaatg tagatattat agaggcactt cataattgaa gtgtcttttt
    19021 gttaatactt attaaatata ttataaagat taataatagt agtttatatt atacttacta
    19081 agtgaatcca agataaatgg gttcactttt tttatttata aacattatta aaaaaatata
    19141 gatgttttgg ttatattcct tgtcctttat aaatagaatt atataaacaa aggaggagga
    19201 caagagatga ataaactttc tgatgaaata ataaactctc tttctacaac tataagagaa
    19261 aaggtagaaa aagtctcaaa caataatctg aacatagaag aaattaggtt acgctcacaa
    19321 aaaccattga tactaaatgc aaactctaaa gattattttt acaatcaaaa aactatgaca
    19381 cttgatttaa atcaacaaaa ctcatatgta gtaacaagag aagatgtaga gcaaactttt
    19441 caaataatat gtaaatattc aatacattca tttatggatg acataaaaaa aggattcata
    19501 actttgagag gaggtcatag agtagggtta gttggaaaag caatagtaga agatggacaa
    19561 gtcaaaaata taaagcatat atcatcttta aatataaggg tatcaaggga aattattgga
    19621 tgctcggata agattttaag tcatattata aagggaaaaa atcagattaa taatactttg
    19681 ataatatcac cacctcaatg tggaaaaaca actttaataa gagatatagt aagaaattta
    19741 agtaatggta atgaagatta tggatttaaa ggtttaaaag tagctttggt agatgagcgt
    19801 aatgagatag caggagctta tctaggtgtt ccacaaatgg atgtgggaat aagaactgat
    19861 ataatagaaa cttgcccaaa agatttgggt attacgatgc ttttaaggtc tatgtcacca
    19921 aatgttattg tgacagatga aattgggagt gaaaaagaaa taaaggcatt atacacagca
    19981 ttaaatggag gtataggatt aataactact gtgcatggag attcaataga tgatatacaa
    20041 aatagaaaag aattaaatag acttctggat aaagagttat ttaaaaaggt tataattctt
    20101 tctgcaaaaa gaggagcagg aacgattgaa aaaatttatg atttagaaga aaagagatgg
    20161 tattttgcaa attaaaataa ttattatagc tctcttggta ggaagtagtt atttgatagg
    20221 tgaacaaata tacaaaactt atactcgtag acataaacaa ttaaacgatt taataagagt
    20281 tttagaaatt ttgaggatgg atttatcttt cggactttat acattagaag aaatctttaa
    20341 taggataggt ggaaataaag agttttgttt ttggaaattt ttctatcaaa tatcagaagg
    20401 acttcacaat gaacaaagta aaactttgga aataataata tcagaaaata ttgatgtctt
    20461 aagtaaagaa acttatctag gcaataaaga aattgaggaa ctgaaaaatc taatacttac
    20521 tttagggaaa agcgatatag agtcacaaca aagaatgata gatttatcta tagaaaattt
    20581 gaaaaaacaa acctatgaga caaaggaaga tataaacaaa aaaggcgtat tgtataaaaa
    20641 attagtgaca ttcataggta taggtatatg tattatattg atttaatatg gggaggttta
    20701 ttatggaaat atcattgata ttaaaggttg caggtgtcgg tattctaata tcagtattga
    20761 atatgatatt ggaaaaaaca gatagaaaag attgggcagg tcttactaca ttagcaggtg
    20821 taataatcgt attgggtatg gtaataacag aaataagtga cttgtttaat actgtaagaa
    20881 caatgtttca actttactaa aaaggaggga gtaatttgga aataatgcaa ttaataggaa
    20941 ttgcaatcat ttcaactaca ctctgtttag taattaaaaa agatagacca gagatagcaa
    21001 atttcatagc aataataact ggagtaataa tactattgtc agttatgttt aagctaaatt
    21061 ttatagtaga tagtatacaa gatttggcta acaaggctaa cataccgact atgtatatat
    21121 cattaataat aaaattaatt gggatagcat acttaatgga atttgcgata caactttgta
    21181 aagattgtgg ggaaggaaac attgcttcaa aactagaatt tggaggtaaa ataatagtta
    21241 tgtcaatgtc tttccctata cttttgtcca ttgtagaaat ggtggtgaat ataattccat
    21301 agatgtgtat cttggaatga atataagtat attagagaac tttcgttgta ttgaggttta
    21361 tagagtgaag agaggcatgg ttgcttatga aaaaaagatt tttaccaatg attataggtt
    21421 ttttatttac tttctttttt gtaaatatct ttgctattat gatatttgct aatgaagtac
    21481 caagtagtga agataaagaa tatggtgaaa caaaaaatag catagataaa tatatagatg
    21541 gtcaattaga caagctagat ataaatgaga ttcaagacta tataaataaa gaaatagtta
    21601 ttaatgatgt taatttaaaa tcatttgtaa aagatttaat tagtggagaa aaaaatatct
    21661 tagatttatt caataaagat ggattgaaga tattgatgtt tgatgaattt aaagcaagtt
    21721 taaaggtagt agcagtaatt ttggtactgg ctctgttatc atctatttta aagagtctgg
    21781 aaaactcttt ttcatcaggt gcagtaagtc aaatagcaac atatataata tttatcacaa
    21841 tggtatcact tacacttatt ggttttaaag atgtattaca gatttgttat gatgcaatag
    21901 accatactgt aggtcttatg caagttataa tgccaatatt aataacattt ttacttttaa
    21961 ttgggttccc aataacgtcg actactttga atcctatctt cataggagga gtaacattta
    22021 taaatgtatt ttttaaaaat tttctatttg tatctattac tgttgcattt ggaattttaa
    22081 taataaacaa tttatcaaaa aatataaggc taaagagatt tttctccttt gtaaaacaaa
    22141 taaattatgt ttctattgga gctatgttta ctgtttactt aggtcttgta tccatacaag
    22201 gattgtatgt aaccagtttt gataaattca gtgtaaagac tgctaaattt gctataggca
    22261 attttattcc tgttgtaggt ggatttgtat ctgactctgt ggatatttta ttatcttcat
    22321 ctcagcttat aaaaaatata tttggaggaa tagggcttat cttacttgtt ggaatttgtt
    22381 tacttccagt aataaaaatt ttatcagtaa tagtagtgta caaattagca gcaataattg
    22441 tagagcctgt tggagaggat ggaatatcta attttttaaa tgaagtggca aatttaatga
    22501 taataatgct agcatcagta attgctataa cagtaatgtt ctttgtaact gtagctatct
    22561 tgacctcgat aagtgtcgta agtcaagggt aatttatata tcagtgaaaa ataattacat
    22621 ttaatctaat gtttttagag aggaggatgc tatgttagag ggcataaagg catggatagt
    22681 tagtgttttg ataggagcat ttatagtaaa tatagtagat atgattttac caagttctaa
    22741 gataaaacct tatgtcaacc tagttttaaa ctttatgttt gtatttattg taataactcc
    22801 agtagtagga tttttttcaa aagatatgag tttagaagat agaatattaa aatctatggg
    22861 aaactacaac aagcagtatg tagatagtac aaatgctttg gcaaaagaga ctggaaataa
    22921 tagtctatcc aagggatatg aggatgggtt aaaagaagta cttaaattaa aacttgatga
    22981 atatggttat gatttagaag atatagagct taatggggca aatataaata atataaaaat
    23041 aaaagaaaag aataatagtg caaaaagtaa taacagttcc aatgaagaaa ataaaaataa
    23101 tagtactaaa agagaggaag aaaacataaa ctctaatgac aaagaaaatt ctaaacaagt
    23161 cttcaaaaaa ggtacagagt atgggttgaa cctaaatgaa gaaaaattaa aaaacgactt
    23221 aataaaggtg ctggatgttt ctatagaaga tatacaaatt gataaatagg agttgggaga
    23281 atgttgaaaa acttaaatga caaagataag agaaaggtat attcactaat aactatagca
    23341 ggaatatgtg tggtttcatt agtattatta tcttgttttc ctaatagcaa aagtgataaa
    23401 caagttggaa aaacagagac taataaaaat gctgaaaagc aagtcactaa aaaacaagaa
    23461 aaagatgatt tagagtcaaa attaacagca atactatcta aaattgatgg tgcaggagac
    23521 gttgatgtaa tggttacatt tgaatcaagt gaagaaatac aacctgcttt taattcaaat
    23581 aatacaacag aaacaacaga ggaaaaagat gcacaaggtg gagaaagaac agttacgact
    23641 tctagtgaaa ataaaacaat gataacttca aattcaagtg accctgtagt tataaaaact
    23701 acagagccaa agataaaggg agtgatagtg gtagcaagtg gagcaagtga cccaagtgtt
    23761 aaagagacac tttatagtgc agtacaaaca tcattacaag tagctggtca tcaagtagaa
    23821 atatattcta aataaataca tataaccggg gggataaatg aatgaagttt aattataagg
    23881 gaagaggatt tgtaataata actttaactg caatgttagt ggtagtagga acagtgaatt
    23941 atcaactaag taagaaatct ttattagaaa catcaaaaga gtttaaggca tatgaagaag
    24001 cacagttgca aaaaaatact gatgatagtg atagtagtaa gacagaggat tctagtaatg
    24061 tagataaaca aggtggtaag gaaagtgctg atattgatat agtcgatagc aaagctagta
    24121 aagtaaaaga aaaggcaact gagacaagta aggaaataaa agctcaatta tcatcagaga
    24181 aaaatatgaa aaaggcatct tatattttag atatgaaaat gaatagagaa aaacaaagaa
    24241 atgagttagt tcaagattta aatgaaatga taaataatcc atctacaaca gaagaatcta
    24301 gaaaagaagc ttctaatatg aaattaaata tagttaaaat tcaagaaaaa gaacttcaaa
    24361 tagaaaacct tttgagtaca aaaggatatg aagaagcgtt agtttatata agcgataaca
    24421 aagttaatgt agttgtaaat gaagctaaat tagaaaagaa agatgcagca aaaatatttg
    24481 atttagttgc agaacaagcc aatgtgaagt atgaaaatat taaacttaca aataataata
    24541 gtaataagta aagtataaac ctcagaatta actgaggtta ttttcttgca aagtagactt
    24601 gtatttggta ttattatact tataaaaata gttccttaaa atcaggaggt aagttttaat
    24661 atggaagata ataaatttgg acaagtaaaa atatctaatg atgtaatagc tacaatagct
    24721 ggtttagcag cattagaagt tgaaggcata gaaactacag caacattaac agataagttg
    24781 ttaaaaaata atggagtaaa aatacaaatc gaagaagagg atgttaattt agatgtaatg
    24841 gttacgataa agtatggaat gtcaatacca gatacagctt ttaaagttca agaaaatgta
    24901 aaaaatactg ttgagacaat gacaggactg aaggtttctc aagtaaatat acacattcaa
    24961 ggaatcagct ttaagaagga taaagttgat aaagaagaag caaaagcaac taagaaaaat
    25021 taatattagc cctctgaaaa gtcagagggt tttttgctgg taattgattt tatatggata
    25081 attaaactta aaggagaatt ttgattgatg aaaaaagata gggcacaaaa gagtacaaca
    25141 agagaatata taatgaaact tatataccaa ataaatatta ataaagaaga ttttgaaact
    25201 ttagaagata aagtagataa ttttttaaaa gataattcag aacatattat aaatagatat
    25261 aaagaacttg cacttcaata ctcaaaaaat acaaatttaa agttagaaga tactgaaatt
    25321 gaagatgtta tagacaagaa atatataaat acagtatgca aagcattaaa agaaaatcat
    25381 gacaaaatag atgagttaat aaataagcat gctaaaaact ggacagtaga tagaatgcca
    25441 aaggtagatg tttctatact tagattgtct gtgtgtgaaa tactttattt agacactcct
    25501 aataaagtat caataaatga agcggtagaa cttgcaaaaa tatattgtga tgataagtct
    25561 cctaaattta taaatggtat attgggaagt gttgttgatg aaattgggaa ataatataat
    25621 aattggaatt gatactagct gctatactac ttctatagca gctatctctt tagataagaa
    25681 agttatattc aatgaaaaaa taatgttaga agtaagggat aattcaaaag gtttaaggca
    25741 aagtgaagct gtatttcaac atatcaataa tttagggatt cttagtgata ggataaaatc
    25801 ttttaaagat aagtttaatg tagaaggagt ttgctcatca aaaaaaccga gacctgttga
    25861 aaactcatat atgcctgtat tcaatgtagg tcataatttt ggaaaattat tgtctagtat
    25921 atatggttgt aggttttatg agactactca tcaagagaat catattgaag caagtttatt
    25981 aaataataaa ttaaaaaata ataataaatt tatttctgtt catatgtctg gtggtactac
    26041 agagatactt ttaacaagca aacaagatag tcatcacaat gtatgtgata ctaatttagg
    26101 taaaattgcc aaaataagta ttaaaaaaga tgataaaagt aagttataca ataattttgg
    26161 atataatata gatataattg gaggaagtaa agatattagc tttggtcaac tcatagatag
    26221 agtaggaatt aagcttggat ataaatttcc ttcaggaaag tatttggatg aaaatgcttt
    26281 aaattgtaat cttaaaatag aaagtggtct gaaaacttct gtaagagatg ggtatatgaa
    26341 tttatctgga ttagaaaatc aggtaaataa gattataaat gataatggag ataatactaa
    26401 tcaaaaagaa tatatatcta aattagtatt agattcagta gttagaaata tgtttaaatc
    26461 tttagtgtat ttatgtgaaa cttataatgt aaatgaagta gtatttgctg gtggagtttc
    26521 tgcaagtaag tatattctta gagagttaag catgaagtta agaaaaaagc atatagaagc
    26581 ttattttaca gaaccacaat attcaactga taatgctgtc gggtgtgcta taataggatt
    26641 gaataacttt ttaggagaaa gagtatgaaa ctaagagctt tagatataag tgaagcaaac
    26701 tcatatatta aaagaatttt aataaacgac ccaatacttt ctaatcttaa agttaaagga
    26761 gaaatttcta attttaaggt tcatagtagt gggaatgtat atttatcact taaagatgaa
    26821 acatcaaagt taaactgtgt aatttttaaa agtaatttta atcgcaattt aaaattagat
    26881 aatggtgtaa aaattatagc taatggatat atatcagtct atgaaagaga tggtgcgtat
    26941 caattataca ttaatgaaat tgaaatagag ggaataggaa atttacacat agagtttaat
    27001 agattaaagg aaaaacttaa taaagaagga ttatttgacc ctaaatacaa gatacctata
    27061 cctaaaatgc caaactcaat tggcgttata acatctccaa caggtgctgt tataagggat
    27121 ataataaatg taataaaaag aagatatccg aaagttaata taaagcttta tccagtaatg
    27181 gttcaaggag ataaatcagc tgaagaaatc tgtgaagcaa ttagattttt caatcatatg
    27241 aagaatgttg atacacttat agttggtaga ggtgggggtt caatagaaga actttggtct
    27301 tttaatgatg aaatggtagc aagagaggtt tttaattctc aaattccgat aatatcagca
    27361 gttgggcatg aaacagattt tactatttgt gactttgtgt ctgatatgag agccccaacg
    27421 ccatcagcag cagctgagat tgctactcca tcattggatg atataaacta taaacttgga
    27481 aacataaaaa gtaggatgag taagtctctt acaaatcaaa tagagctaga ccaatatagg
    27541 ttagaaacag tatttaataa gataaataac tatttagatt cgtacacaat aaaagataaa
    27601 gttatacaat tagacaaaat atatgataaa ataatttttg gaatagaaaa taatttaaaa
    27661 ttagaagatg aaaaattagt aaaaattgga gcattactcc ataatttaag tccattagct
    27721 actatggata gaggttatag tataactcaa aaaaatggaa aagtaataaa tagtataaaa
    27781 ggattaaaaa taaaggatag tatagatata gtattaaaag atggaaattt agaatgtatg
    27841 atagataaaa ttgaaaataa agagggatag tatgaattta acctacgaag aagcttataa
    27901 aagattagaa agtattttaa gtgaattaga atctaaaaat gctagcttgg atgaatcttt
    27961 aagcctatat gaagaaggta taagccttta taaacattgt aataagcttt tagatgatgc
    28021 taaattgaaa ataagtaaat ttaatcaatt aggaatagaa gaagacttta aaatagagga
    28081 ggaataaaat tggaatttaa acaatgtcta aaagaaaaag caagttttgt agaaaaagta
    28141 cttaaagaat atatgcctaa agaagaaggg tatcaaaaaa ctgttattga agctatgaac
    28201 tatagtttaa gtgctggagg taaaagatta agaccaatac ttacattgga ggcttgtaaa
    28261 atagttggag gaaatgaaga tgaagctatt ccttttgcta ttgcaattga aatgatacat
    28321 acatattcac taatacatga tgatttgcca gctcttgaca atgatgattt aagaagagga
    28381 agaccaacaa atcataaagt atatggagaa gctatgggga ttttagcagg agatgctttg
    28441 ttaaactatg cttttgaagt aatgcttgca ggctcaatca ataaagaaaa tccagaaaag
    28501 tatctaaaag ctataaatga aattgccaaa ggtgctggta tatatggaat gataggtggt
    28561 caagtagtag atgtagaaag cgaaaataaa caaattgaaa aagaaaaatt agattatata
    28621 catatgaata aaactgctgc aatgatggta ggctgtatga gagcaggagc tactataggt
    28681 ggagcaaatt ctgaacaaat ggaagaaata actaaatatg caaaaaatat cggattatca
    28741 ttccagatag tagatgatat actagacata gtaggagatg aagctaagtt aggtaaaaag
    28801 gttggaagtg atatagaaaa tcataagtca acatacccat ctcttttagg tttagataaa
    28861 tctaaagaaa ttgcacataa tttgattgat gaagcaaaga aaagtataga aaaattatct
    28921 gatgatgtag attttttaaa gggattggct gaatatataa tagatagaga atactaaaat
    28981 atacagctaa aatcgaggag ggaaaaatgg attttttttc ggagattttt aacaatgggg
    29041 ctttgggaat aagtctgatt gcttgtttct tagcacaatt tataaaaata tttactggta
    29101 aggaaaaaag aattgagtta tcaagaatac ttatttcagg aggtatgcct agttcccata
    29161 gttcttttgt tacaagttta gctacagtgg taggtattga aaaagggttt aattctactg
    29221 attttgctat aattaccgtg cttgccttaa ttataatgta tgatgcagca ggtgttagac
    29281 gagctgttgg taaacaagct actatattaa atcaaatggt ggcagatata cagcatggaa
    29341 agcatataga gcagaagaaa ttaaaagaat taataggtca tacaccacta gaagtttggt
    29401 ttggagcttt acttggaata gtaacagctt taatattgat gtaaattgaa aatttacaga
    29461 ataaaggtga ggataatatg tataaatatt tagataaagt aaattctcca aaggatataa
    29521 aaaatatgag tatagaagaa atggatttac ttgcaaagga tataagaaag ttcttagtaa
    29581 aatctgtttc aaagacagga ggacacttag cttctaatct aggagtggtt gagttaacat
    29641 tagcacttca taaagtattt gatagcccta aagataagat tgtatgggat gtagggcatc
    29701 aatcttatgt tcataaaata gttactggaa gaaaagattg ttttgtatct ttgagacagt
    29761 ttaatggact aagtggtttt ccaaaggaga atgaaagtcc tcatgatatt tttgatacag
    29821 gacatagcag tacatctatt tctatagcta caggtattgc ctgcgctagg gatataaaaa
    29881 aagaaaacta tagtgttata tctgtgatag gagatggttc tataacagga ggtatggcac
    29941 ttgaagcttt aaatcaatta ggatatatag ataccaatat gatagtaatc cttaatgata
    30001 atgagatgtc catagataaa aatgttggag gaatgtctaa atatctgtca agtattataa
    30061 gaaactcaac agttgagaaa atgacagatg aagttgataa aattttaaat gttacacaaa
    30121 caggtgaaat tttatctaag actgcacata gatttaaaga taaactaatg tatagctttt
    30181 ctcctcagga ctgttcattt tttgattcat taggtataag atattatgga cctatagatg
    30241 gccataatac taaagaacta atagatatat tgagaaaatc taaacacaaa aaagggcctg
    30301 ttcttttaca tgtaattacg aaaaaaggaa aagggtacag atttgcagaa gaacaacctg
    30361 ataaatatca tggagtatca aagtttgata taaagacagg tgttacatct gcaaaagtta
    30421 agtctatgtc aattagtgtt ggagaaaaac ttgttgatat ggctaataat aatgaagata
    30481 tagtagcaat aacagctgca atgccatctg gtacagggtt aaacctgttt gaaagtgcat
    30541 atccaaaaag atattatgat gttggtatag ctgaacaaca tgcaacagga tttgcagcag
    30601 gtcttgcaaa aaatggtatg aaaccttact ttgctgtgta ctcatcattt ttgcaaaggg
    30661 catatgacca agttattcat gatgtatgca taacaaaaaa gccagttact tttcttatag
    30721 atagagctgg attagttgga aatgatggag aaactcatca tggtatgttt gatttaagtt
    30781 acttaaattc tattccaaat attgtagtaa tggctccaaa agacacaaga gagatggagc
    30841 ttatgatgga tttgtcatta aaattagatt gtccactagc aattagatac ccaagaggaa
    30901 gtagttatta cctagataag ggagaatatg gagagattgt actgggtaaa tatgaggtat
    30961 tagatgacgg tcaagataca gttatacttt gtattggaag tatggtaaaa catgccttag
    31021 aggctaaaga aatattatca agagaaggaa taaatccgac aatagttaat gctagattct
    31081 taaagccaat tgatgaaggt atgttaaaag cattattaaa aaatcataaa aatttagtta
    31141 ctatagagga taatattgta actggaggat ttggaagtag aataaacaag tttattatag
    31201 ataatgaata taacgtaaat atacttaata tagcaatacc agaagaattt gtaaaacatg
    31261 gcaatataga tgaattatat gattttgtag gattatcgcc aaaaagtatt gctgataaaa
    31321 taaggaaatt agttattgag taaaaatcta atgtagatat tgtaaattaa aatttatata
    31381 aaatatagaa tttatcaatt agaataaata tcaagtgtgt tacttcaagc tactttagtt
    31441 atcattaaag tagcttttaa cagaaaggta attgtatgaa aaaaagaata gatttgttat
    31501 tagtagaaca agggtacttt gaaagtagag aaagagccaa aaaagcaata atggctggat
    31561 tggtttttgt tgataatcaa aggtgtgata aggctggtac agaagtaaaa gaagattgta
    31621 gtatagaagt aaaaggaaat ccaataccat atgtcagtag aggtggttta aagcttgaaa
    31681 aagcaatgaa aaactttaat ttgactattg atggaaaggt atgtatggat ataggggcat
    31741 ccacaggtgg ttttacagat tgtatgctca aaaatggagc aataaaagta ttttctatag
    31801 atgttggtta tggtcaactt gcatggaaat tgagacaaga tgatagggtt gtgtgtatgg
    31861 aaagaaccaa tataagaaat gtgacaatag aagatacaaa gcagtttgct gattttgcat
    31921 caattgatgt gtcttttata tcgttaaagt tagtacttcc aaaggcaaag gagttaatac
    31981 gtcatgatgg ggaagttgtc gctttaatta aacctcaatt tgaagcagga agagaaaaag
    32041 taggtaaaaa aggagtagtt agagaaaaat ctacacatat agaagttata aaaatgattt
    32101 ctgatttctc agtcgaaaat ggatttgaga ttttagggtt agatttttct cctattaaag
    32161 gtcctgaagg taatatagaa tatctaattc atttgagaaa tggaaatgaa ggatatgaat
    32221 ttgatggtga gacatacaat aacaaaatag tagaagttgt tgaagcttct cataatttag
    32281 acaaataggt taaaaggggg cttagatttg atcctcgaat tatatatgaa aaattgtgcc
    32341 ttagttgaag aactaaggtt gaatattgat aaaaacttaa atatacttac aggtgaaact
    32401 ggttcaggaa aatctataat aatagatgca cttggacttt gtttaggtga taaatatgat
    32461 aggtcttttt taagaaaagg aacagataag ggacttgttg aggctgtatt tttttcagac
    32521 aatagatatc ttaaaaaaat attagaagaa aatgatataa gtatggaaga tgataattta
    32581 ttggtaataa ctaggttgat atactcagat ggtaagagta ctgctagagt aaatggaagg
    32641 actgttaaag tgtctcttct taaagaaatt gcatctacac ttatagatat acatggtcaa
    32701 catcaaaatc aagctttgtt caataaagat actcatttaa aatttctaga cctttttgga
    32761 gaaaatgaat tggaagagtt taaaattgct tataaaaatg tgtaccataa gtatagtgaa
    32821 gtaaaaaaag ctttaaattg cttgacagaa aataaagatg agatgcaaat tcaacgagaa
    32881 atagatttat taagatttca aataaatgaa attgaagctg caaatctaaa taagaatgaa
    32941 tatgaagatt tattaaaaca aagagaagtt tatagaaata gtgaaaagat atataataat
    33001 ctaaattcga gttatagcaa gttacataat ggtgagtata atgttattga cctaataggt
    33061 cttgcatcta aggaacttaa tgacatatct aaatatgaca gtgttttaag tgaatatagt
    33121 gatactgtag aaagaattat gtatgagtta caagacatat ctggtgagat aagaaattac
    33181 aaagataata tagactttga accttatgag ctagagcaga ttgagcttag aatcgacgaa
    33241 attaataatt taagaagaaa atatggagac agtatagatg atatatttga gtattatgga
    33301 aaaattaaag atagattaga tgaaatatta aatagagatg aaagagttga acagttaaaa
    33361 agcaaactga tgaatataga agaagattta aaaataaaag ccagtaaatt gactaaagca
    33421 agaatagaag tagcaactac tttagaaaaa atacttcttg atgaattaaa aagcttaaat
    33481 atgaaaaatg taatgttcaa ggttaatttt gaaaaaggtc catttacttt agatggagta
    33541 gatgatattg aatttatgat atcttttaac ttaggagaag atattaagcc tatatataaa
    33601 gttgcatcag gtggtgagat gtccagattt atgttagcgt ttaaaaccat attggctgat
    33661 atagatgata ttgatacatt agtgtttgat gagatagata ctggaataag tgggatagca
    33721 gcacagatag ttggtgagaa attgagtgat atagcaaaga aaaaacagat aatatgtata
    33781 actcatttac ctcaaattgc tgcaaatgca gacactcatt attgtataga gaaagatact
    33841 tcaaataata ggacgtttac caatgttagt aagttaaatg aatctcaacg aaaaaatgaa
    33901 attgccagac ttatagcagg taacaatata acagaaaaaa ctattgaaca tgcaagtgaa
    33961 atcattgaat tggctaaaaa atgttagtga aaaacaagca ttttaatagg tgtaaagaat
    34021 ttttatagaa atgctttaca cctatttttt ataatgaaat tattttaaaa tatctagtgc
    34081 ctatattgaa gaaaagtagg tttgaaaatg gaatgaactt tgtataaatt tgtaactttg
    34141 aaatttataa atgcttaagt ataatattat ttattaaggt agtagtgagg ggaggcataa
    34201 aatgaataaa aaagatacta tgcacttaat ttttataatt gtaattttta ttttattatg
    34261 gtatattgtg gtagcagtaa gtgagattaa taaaaatatt gaaagttgta gtaacaaatt
    34321 agattatttg tcacaagagc ttatgagtac taagtcggat attagtaata ctataaatga
    34381 agaaatgtca aaaagctata taacaaaaag tattgactta aaagtaaaaa aaatcgagaa
    34441 aaaagaatgt attattgata tagatgttca attaagtaaa cttggaaaaa atggaaaagt
    34501 attttttatg tataaagaag atagtgataa atggaatgaa actgagatga caaaacatgg
    34561 agaattatca tatgcatgtg aaattaagat aaatacagga agtgaatatg actataaagt
    34621 agttacaagt ggagctatat ctgaaagttc tgatgtgcaa aaattgacta aatctgatta
    34681 tatgcctgaa caacccatat ttaattctgg gataagagat aatagagaat actttattga
    34741 aatagtagaa aatagtaatc ttttcaatca tgagagtgaa aagtcaaaaa ataaagttta
    34801 tgataatatt agattagaaa aagtagatat tattgtaaat gaaggaaaaa aagacactat
    34861 atacaaagcc aaattagctg aaggcttaga tgatggcaaa actaataatt caaatagaaa
    34921 tcaagtgaat tatgaagtaa gttttcctaa aagggatatt gatgacataa tttatattaa
    34981 agctaaactt acatacaata atggagtaga atatacaaag gatataactg aagatataac
    35041 tatgggatta caagatttag aaaaataaat acatatttaa ataaatattc aaatagattt
    35101 gttcacaaat agagtataaa taaaactgta gtagttttac ttatactcta ttaaaaaatt
    35161 ataattttaa ttccatatat ctagcccctt caattggatt ataagtataa ggttctatat
    35221 cataaaaacc aaacttttca tataatcctt gtgcactttt catgcttgga agagtatcta
    35281 atctcatgtg tgtatatcca atttttttag cttctacaat gatttcttcc aatagtattt
    35341 ttcctatttt taatcctcta aattgatttc ttacatataa tctttttaat tcacatattt
    35401 taccttcaag tttttttaaa gcaacacaac ctgccaaatt ttcatcaaca aatgccaata
    35461 tcaatgaacc tgaaggtttt ttatattttc ctggaagtgt ttttaattca ttattaaagt
    35521 cttgaaaaca taagtctata tttagagaat ttgaatattc agtaaataga agttttacgt
    35581 tttcaaggtt ttctaaatct ttttcttcaa taaattgtaa agttatattt tgagccattt
    35641 tatccgccat tatataaaca tgtttatata atgacttcac ctccttgata tatgtatatt
    35701 tttcttaata tcaattagat tttaatacca ttactttttc accaccatag tcaagctctc
    35761 cattaaactc aaatccaaaa tctttataaa gcttaatagc cattttattg tcttcgaata
    35821 tactaagata tagttcatca cagttatatt catttttaag atgatttaca agaaaatcta
    35881 atgatgcttt tccatatcct ttaccttgat attttgaatc aatcataaat ctatcaagcc
    35941 aaactctatc atcttctaaa cgaccataca tagcaaatcc tattaaagaa ttttcatcat
    36001 atattccaac aggtacccaa gctgttataa atttagattc agcaatagaa agtgcattgc
    36061 tttctatata atctaactga cttttatcta cagacaaact aattaaatca tgccaattat
    36121 ttatgtctgc aattcttaca tttaatttca agatattacc gcccttcaaa ctttttgtta
    36181 caatctaata ctatcatatt atgtattaaa aatcacttat taagatttta aataaacttt
    36241 ttgaatgaat aaattctcag gaaaaaggaa ttataaatac ataataatac agcataggag
    36301 tagatggata tatgaacaaa ataaataaaa atttcaaaaa tatttggata atattaggag
    36361 ctgtatcgat ttttaccata gttataattt ttaataaaaa ttgtaatgtt aataaagaga
    36421 ctcaaataga agcttttaca attaagaatc atgataaaaa atttgtatat cctatgggaa
    36481 atataattgg agtaaaagca aatacagatg gtgtattggt cttaggatat gaggaagagg
    36541 atgtagacta tattggaggc atacaaatcg gtgataatat agtaaaaata gataataaaa
    36601 ggataaaaaa tagtcaagat gtatcagaga ttttgaataa tattaaaaaa agtaaagttg
    36661 aagtgacttt tgagagaaaa aatacgtata aaacagaagt aatagagact aaaaaagaaa
    36721 atggcaagta taaacttgga ttatgggtaa gagataaaat atctggaatt ggaactatga
    36781 ctttttacga ccctagtatg gaaaagttca aagcaatcgg tcatgccata aaagattcgg
    36841 atactaatga actattaaag ataaagcaag gatatatata taagccagaa caattaaaaa
    36901 tagtaaaagc tagtaatgaa aaagtaggta aaataaaagg agattttaat gacagcaatt
    36961 taatgggtaa tttctcaaat aattcagagt taggtataag tggtaatatt acagaaaacc
    37021 ataataaaga gtttaatgta gcaaataaag aaaagcaatt aatagaagtt ggaagaccgc
    37081 aagatgtaaa aataggagat gcagtaattc tttttgagga taaaaacaaa aatataacaa
    37141 gctatgatat aaaaatagaa agtatagtat atgataaagg aaattataga gatatggtaa
    37201 taaaagtagt agatgacaag ttattggaat acacaggagg tatcgtacag gggatgagtg
    37261 gagctccaat aatacaaaat aataaaatta ttggtgcaat aactcatgtt tttagagata
    37321 atccgaaaaa aggatatggt atttttatag atgaaatgat aaaattgtag gtgaggcatt
    37381 aaaaaatttt attattttat caattatcta ggaggaatat aattttggag tgtcgaatat
    37441 gctttagagt agataattag gaagcaattg tgtaaaaagt ttagttttct gtaataagaa
    37501 gatgtttttt aatgggggga tttttagtgg aaaaaatcaa aatagtttta gcagatgaca
    37561 ataaggattt ttgtcaggta ttaaaagagt atttgtctaa tgaagatgat atcgatatat
    37621 taggcatagc taaggatgga attgaagcat tagacttagt aaaaaagaca caaccggact
    37681 tattaatact agatgtaata atgccacatc tagatggatt aggtgtaatt gaaaaattga
    37741 atactatgga tatacctaaa atgccaaaaa taatagtact atcagcagta ggtcaagata
    37801 agataactca aagcgcaata aatctaggag cagattacta catagtaaag ccatttgatt
    37861 ttgttgtgtt tataaacaga attagagagc tagtttctaa tagagttaca caagttgagc
    37921 caaaacctag accagttcaa gagactcaaa tgactagaag tgattttgtt aagaatgtag
    37981 gaaatataga gacagaaatc acaaatataa tacatgaaat aggagtacca gctcatataa
    38041 aaggatattt atatttaaga gaagcaataa aaatggttat tgataatgtt gagcttttag
    38101 gtgcagtaac aaaagagtta tatccaagta tagctaaaaa attcaataca acaccaagta
    38161 gagttgaaag agcaataaga catgcaatag aggttgcatg gagtagagga aaagttgaca
    38221 caataaatca attatttgga tatacggtac acaatactaa aggaaaacca actaattcag
    38281 aatttatagc aatgattgct gataaattaa gactagaaca tagtatggtt aaataaacaa
    38341 gacataaaaa gtaaggcttt ttaattaagg cattggctat aaatgcgtat tacaagcagc
    38401 gaaacggtat aaccactagg gttataccgt ttcgctattt taataaatat aaaaattttc
    38461 tttattattt gcttactata tcaatataat aattttatta tactatggat atagtatgtg
    38521 tctttacaag ttgtaaactg acagtggttt attttttaat ataaatattg actttgatgc
    38581 aggtaaactt tgtattttta agcgtattat ggaatatgtt aaataaaaaa atgatgaaat
    38641 atagtattgt aaatgacaaa gatgcaaaac aaacttaaaa catttatttt attgttaagt
    38701 aatgctataa tataatgtga ttttaataat gatagtggag gtttaaatat gagagtcgag
    38761 gcccctataa aagtagatcg aaaaaccaaa aaacttgcta aaagagttga aagtggggaa
    38821 atagcagtta taaatcatat agacatagat gaagttgctg caaactcttt agtagaagct
    38881 aaaataaaac ttgtcataaa tgcggctcct tctataagtg gtaggtatcc caataaaggt
    38941 ccagggatat taactgaaaa taatatacta ataattgata atgttggaga agagttattt
    39001 gaagaattaa aagaaggaga aactatagaa gttgtagatg gaaagatata tagaaaagga
    39061 aaatttttag gtgcaggaga agttttagac aagtatgagg tttcacacca aataaaggct
    39121 gcctatgaga atttagctgt agaattggat agatttatag ataatactat agattatgct
    39181 aaaaaagaaa aaggatttat acttggagaa gtagaaattc caaaagtgaa aactaattat
    39241 gctaataaac atgtattgat agttgtaaga ggtcaggact acaaagaaga tttaagtact
    39301 atgctttctt atatagaaga ggtaaagcca gtattggttg gtgttgatgg aggagcagac
    39361 gctttaattg agtttggata tactccagat gtgattgtag gtgatatgga tagtgtaagt
    39421 gatgaagctt taaaaaaggc tagtgaaata gtagtacatg cttatacaga tggaagagca
    39481 ccaggtctta agagggttga ggaattaggc ttagatgcag ttgtatttcc tgcgccagga
    39541 actagtgaag atatagctat gcttatcgcc tatgagtata aggctgagtt aatagtagca
    39601 gttggtacac attcaaatat gattgatttt cttgaaaaag gaagaaaagg tatggcaagt
    39661 acttttttag ttagactaaa aataggttca aagcttatag atgctaaagg cgttaatttg
    39721 ttatacagaa gtaaattaaa aataaagtac atatgggcat taatagcaac agcattattt
    39781 cctgtgttgg tagttgcatc attgtcacca ggagttcaac agttcataca actaatgcaa
    39841 ttaaagttta gagtattatt acagatgtaa attttaggag gataaatatg catattaata
    39901 tgaaatatta tatagtcact ataggggcta tatttatagc tttgggtata ggcatgttag
    39961 taggatttaa tttaaataat aatcaacaat taagtgaaca acaagcaaac ataataaatg
    40021 atttggatga taagtttaat atcttaaaag aaaaaaatga taaacttgac agtgacttag
    40081 caagtgtaaa tagagattat gaagaggcag ttaattttat aaataaaaat gtagataaga
    40141 ttttagctgg ttcgctgaat ggtaaaagta taggaataat atcggctaat gaaaatgacg
    40201 attatacaaa aaatatagaa gacataataa ataaatctaa tggaagtatt gcatttaata
    40261 tagtattaaa agaaaatata acaaatccag aaaagttaaa ggaaatgtca actaaactag
    40321 gtacagatgt aaaaaatgca aatgatgcag ttaattatat aattgacacc cttaaaaagg
    40381 aagatgcaag tgacatttta acatatcttc aagaactaga tgtaataaag tttaactctc
    40441 ttggaaatac atatctaaaa tatgattctg ttgtaatagc tggtggaaat gatgcaaaag
    40501 acagtacaaa acagtttgaa aaaatagaaa aatttgtagt ttcaaaactt aaatcagaga
    40561 ataaatattt agtagaagtt caaaatacag gagttaaaac ttcttatgta gaactatatt
    40621 ctaaaaacaa agttgcaact atagacaata ttgatgaagg tataggaagt atatctctag
    40681 ctattcttct acaacaaggt aatatagttg gtaattttgg tagattggat actgcaactt
    40741 cattgttgcc atctattaaa tagaaataat tttaaggaga gaaaaaatgg attcttatat
    40801 aagtataata ataccagctt ataatgaaga aagtagaata aaatatacat tagaaagcat
    40861 attggacatt aagcaaataa atgaaataat agttgtggat gatggttcaa ttgacaatac
    40921 tgctaaggtt gtatctgagc tagaaaatgc aaagattaaa ttttttaagt tagataaaaa
    40981 tagaggtaaa ggatatgctt taaattatgg tatcaaatta gcaatgaaaa atgcagatat
    41041 tataggtttt ctggatggag atttaggaag ctctgctaaa gaagttgaaa aattaatagt
    41101 acctatatta aatggtgagg cggatgttac aatagccaag tttcctcctg caaagagaaa
    41161 aggaggtttg ggatttgtaa aaggtttagc taaaaattct gtgtttgaga tgactggtgt
    41221 tgagttagat gcaactttgt caggtcaaag aatatttaaa agagaagttt tagaaaagtt
    41281 tgatgaaata ccttttggat atggagtaga agttggaatg accattgata tattaaagta
    41341 tggatttaaa attaaagaag tattagtaaa tatgactcat aatgaaacag gaagaaattt
    41401 aaaaggtttt attcatagag ggaaacagta ttatcacata aaaaaggttt taggacaaaa
    41461 aaagaaagaa tggaggtaat atcttagtga aagattatat actttatacc attttattat
    41521 taactggatt atttggaacc tatgctgtaa ttccactatt taaaaattta ttgataaatg
    41581 gaaatgtact tagaccaaac tataaaaaag atatgatacc agtaagtatg ggaattgtat
    41641 ttttgcctat gattgtaatc aatggaataa tacttgcttt ctttactaca gaatttaagg
    41701 atttagcgta tatatttatg tttatgtttg gaatgatatc catgtttttt gcagggatac
    41761 tagatgatgt cattggaaat agagatgtaa gtggtttaaa ggggcatttt aaaagtttat
    41821 ttaaaggaag tcttacaaca ggaggtttta aagctttatt tggtggattt gtagggctta
    41881 tagtttctgt tgctatatca aaagacataa ttgatataat agtaaataca ctaataatag
    41941 ctctatcaac taatttaatg aatcttttgg atttaagacc aggaagggca ataaaagcat
    42001 atttattcat aatggtaatt atatttttaa cattgacagg atttgttcaa gttcttccat
    42061 tacttatagt accaaatgta cttgcatact ttaattatga tttaaaagca agggctatga
    42121 tgggagatac tggttcaaac gtccttggaa tatctattgg aatgctcatt tcttttgggt
    42181 atccatttaa cattagatta ggatggttaa tatttgtagt tattatgcat atattcactg
    42241 agaaatactc attaactaag ataatagaaa aaaataaact attaaatttt atagataaat
    42301 tgggaaggta gtattatgat aagcaaaaga gtggggattg ttgaatcaat agtaagtcaa
    42361 actgaaactc tagatgatat aagagtaaat ataaatggaa aaatacaaag ggcatataat
    42421 tatcccaaaa tatctggaac tataaatata ggtgatgaag tggttttaaa tacaacagca
    42481 gtagaactga gcttaggtac aggtggatac cattttgtaa taactaattt aaataatata
    42541 gaatctactt taactgaagg tgggcatata atgaaactta gatatacacc tcttcaaata
    42601 aaagtggatt ctgttgagga acaagaaagt atttatcatg ataaatttgc gaattttaaa
    42661 ggattagaag gtctttctgt tgtagtaggg actcttcata gtatgttaac tccatttgca
    42721 gcttcattta aaagaaataa tccaaataaa aaattagtat atataatgac tgatggagca
    42781 tctcttccaa tttatttaag taaaaatgtg gacactttaa aagaaaaaaa attaatagat
    42841 agtacgataa ctataggaaa tgcgtttggt ggagattatg aatgtataaa tatatatact
    42901 gcattaatta cagcaaaaga aatactaaaa gcggatgcag tatttgtcag tatgggacct
    42961 ggaattgctg ggacaggaac aaaatatgga tttacaggga ttgaacaagg ctctattctt
    43021 gatgccgtaa aaaaacttga aggaagagca attgcaattc caagaattag ttttgctgac
    43081 aaacgagaaa gacatcaagg tatttcacat catagtatga ctgtatttaa agaaattgta
    43141 aatgtaaatg tagacatacc aataactata tatgatgatg aaaaattgaa ctttataaaa
    43201 gagcaaatca atttaaatgg tttagacaaa aagcataata taatttatat agataataat
    43261 aaaacgaaag aggatttaga ctattttaat ctaaaagtaa agagtatggg aagaaattat
    43321 gaacaagatg aggcattttt caaagctgca agcacagcag catattactt aatggaggtt
    43381 taagatggta ttagaagaaa aaactattag tagtgatagg gtttatacag gtaaagtaat
    43441 tactttaaag gttgatactg ttgaaattcc agggcaagga tatcaaaaaa gggagttagt
    43501 agaagttggt ggagcagtag gaatagttgc aatcacagat gataataaag ttgtactagt
    43561 taagcaattt agaaaaccta tagaaaagcc aatctttgaa attccagctg gtaaactaga
    43621 aaaaaatgaa agtccaaaag aatgtgctga aagagaatta aaagaagaaa ctggttatag
    43681 tgcaaaaaat attaagctaa tacataaatt tttcacttca gcaggttttt ctaatgagat
    43741 aatgtttgta tatttagcaa caggtcttac tccaggagag aataatttag atgcagatga
    43801 gtttttagat gtctatgaaa ttgagcttga agaagcatat aacatggtat taaaaaatga
    43861 cgttgaagat gcaaaaacat ctattggatt attattagta aaagatatgt ttaaaaatta
    43921 atatttataa aatgaataac cctttgtcct aaagcatatt attttataaa ggacaagggg
    43981 gaattaaatt gagaagaaca tatagaaaaa atgattttag agaactaaat agacaaataa
    44041 ttattatagg attgttgttt atgatgtcta ttgttgttgg gtcttacata aataaaatat
    44101 tgccaggttc tagtaacaat atattaaaca atataaatcc tgctgtagag tattataatc
    44161 taaatataag cataaaagat acagtgatac aaaatttaaa atcagatgca atctttatgg
    44221 gctcaatagc tctattaagt ctatttgtag taacaattcc agcagtgttg gtagcttttg
    44281 tattaaaagg gatgtcaatt ggttatacaa taaatagttg tatattggca ttaaaattta
    44341 aaagtataaa aatgatttta ataatattat ttaaaaattt gattattatt ccatgtgcaa
    44401 tcatattagc attaattagt ttaagttatt ttaaagaaat ggtttatgaa tttaaaaaga
    44461 aaaatagaaa aaatatgcaa tttttaatta agaggtatat actaaatatt ataattataa
    44521 tagcactatc attggggttg caattaatat taaatactgt aagtattggt attattaagt
    44581 tcctagctaa ataaaggagt ttataatgga tattatagag ggatatatag attacataaa
    44641 agataaaaaa aaattatcag agaacacagt ggcatcatac tttatggata taaaaaaata
    44701 tatggaatat ataaatcaaa aaagcattaa actagtagat atagtagaaa atgatattat
    44761 aagttactta ataaagttgg aaaaagataa tgtatcaata gctacaatag cgaggatgat
    44821 atcctctata aaatcttttc atgattattt atttttaaat catatatgta caaataatcc
    44881 tgcaaaggat ataaaaaaac ctaaaataaa aaaagaaaat ataaatatac ttacagaaga
    44941 agaaattgaa agactattaa attttccaaa gttaacaaca cctaaattga ttagggacaa
    45001 ggctattttt gaagtattat atggtactgg tataaaagta tctgaattag tagagatgaa
    45061 tatagaggat attgacctag atattgatta tatatattgt aattcatgtt gtaaaaatca
    45121 aagagtgata ccactttgtg atattacaaa actttactta gaaaagtatc taaaagaagc
    45181 aagacctaaa atggctgtag aaggtgaaaa atcattattc gtaagttcat taggtcaaag
    45241 gtttacacga caaggtcttt ggaaagtcat aaaaaaatat tctaatctag ccaatataga
    45301 taaaaatata aatcctacaa tgcttagaca ttcatttgct attcatttgt taaatgaagg
    45361 tgctaacatt gctgttgtaa gtaaaatttt aggaaatgtt aatttatcta gtttgcaagt
    45421 atatttaaat catatagata aaaacgtgag aagagaaata aaggaaaaac atcctagaaa
    45481 tgatgttgat gtagaattac aaaaagcaga agctaaatag actatatagc aaattttata
    45541 atttagaagg agcatattta tatgagcaga gtaatttgga ttgtaattga tagtgttggg
    45601 ataggagcat tacctgatgc tgaaaaattt ggtgatagta aggatgtaag tacccttgga
    45661 aatatattta aggaatatcc agatattcag attcctaata tgagaaattt aggtatagga
    45721 aacatagatg gtatagattt ttttgaaagt ataaaagaac caataggttg ttttggaaag
    45781 tgtaaggaaa tgtctcaggg aaaagatact actacaggtc attgggaaat gactggtata
    45841 atagttgaca aaccatttaa gacatttgaa catggattct ctaaggagat aatagaagag
    45901 tttgagaaaa aaactggaag aaaagtagta ggaaataaac cagcttcagg aactgtaata
    45961 atagatgagt atggagagca tcaaataaaa actggagatg taatagtgta tacatcagct
    46021 gatagtgtat ttcagattgc tgctaatgaa gaagtaattc ccctagaaga actctataat
    46081 atgtgcaaaa tcgctaggga aataatgatg ggggataatg cagtagctag agtaattgct
    46141 agaccattca taggtaagaa aaaaggtgag tttgtgagga cttcaaatag aagagattat
    46201 tcactagacc catttgaacc aacagttctt gataatataa aagaatcagg acttgatgtt
    46261 ttagcagttg gaaaaataga agatattttt aatggaaaag gaattacaga tgctatccac
    46321 actaaaagca atatggatgg agtggatgaa actttaaatt atatgaaaca agataataaa
    46381 ggtctaatat attcaaatct cgttgatttt gattctaaat atggtcatag gagagaccca
    46441 gaaggatata agaaagctct tgaagagttt gatagtagac ttcctgaaat aatggctaat
    46501 atgagagaag atgatatttt aataatcaat gcagaccatg gaaatgaccc aacatataaa
    46561 ggtacagacc atacaagaga atatatacct gttatgattt atggcaataa gattaaaaaa
    46621 ggttttaatt taggagtaaa agatactttt gctgatattg gagcaactgt tgcagatata
    46681 ctaaatgtaa agttgcctaa acatgggtca agctttaaag aagatttatt ttaaactata
    46741 aaatgataaa aacttagctt aataggatgg agagattgga atgtttgaaa agatagcaca
    46801 aagtagtaaa tttataaatt ctaaaagtaa tataaaacct aagattggtt tgatattagg
    46861 ttctggacta ggtgatttag caaatgatat agaagaccct gtcacaatta aatatagtga
    46921 aattccaaac ttccctgtat caacagtagc aggacatgct ggacaacttg taattggaaa
    46981 acttgaagga aaagaagtta ttgctatgca aggtagattt cattactatg aaggatattc
    47041 tcagaaagaa gctacttttc cagtaagggt tatgaaagaa ttaggagtcg agattcttat
    47101 agtaactaac gctgctggag gcgtaaataa agaatttaaa gcaggagatt tgatgcttat
    47161 aagagaccat ataaacttta gtggaagtaa tccattagta ggaaaaaatg atgacagatt
    47221 tggtgctaga tttccagata tgtcggatgc atattcttct aaatatgtag atgtagttaa
    47281 aaactgcgct aaagaatgta atatagatgt caaagaaggt gtttatatgt tttttagtgg
    47341 tccaaactat gaaacaccag cagaagtaag aatggcacaa attttgggag ctgatgctgt
    47401 aggtatgtct actgttccag aagtcatagt agcttctcac tctaatatag gagttattgg
    47461 tatatcttgt ataacaaata tggctgctgg catcttaaat caaccactaa gtcatgagga
    47521 agtaatagaa actactcaaa aagttaaatc agaatttatg aatttagtta aaacaacggt
    47581 taaaaattta taagttaaaa cttattatag attttttgag gaagtttata ataaaatagt
    47641 taatgtttaa tttgaaaaga attaataaaa agctgtcttg atatagaaag ttatttctaa
    47701 taaaggacag tttttttata atactacaac atttgaaagt gttttaaagt ttaatattta
    47761 tttaaattat tataggttag aatggagatt tcaattatga gaatgtatga tattataaaa
    47821 aaaaagagag ataacttaga gcttagtaaa aaagagataa actactttat agaaaactat
    47881 tcaaagggag atatacctga ctatcaagct tctgcactat taatgtcgat ttatttaaat
    47941 aagatgaata aacaggaaac tgtacatctt acagaagcaa tgatgaactc tggagacatg
    48001 ataaacctgt ctgaggtaga tggaataaag gtagataagc atagtactgg tggtgttgga
    48061 gataagacta ccatagctct tatacctttg gttgcttcat gtggagcacc agttgcaaag
    48121 atgtcaggta gaggtcttgg tcatactggt ggtactattg ataaattgga gtctatacca
    48181 ggtttttcga cagaaatgga gataagtaaa tttattgatt ctgtaaataa gtctaaaata
    48241 gcagtttgtg gtcaaagtgc aaaggtagca attgcagata agaaaatata tgctcttaga
    48301 gatgttacag caactgttga taatatatca ttgatatcat caagtgtaat gtctaaaaag
    48361 ttagcttcag gagctgatgc aattgtgtta gatgtaaaaa ctggtgatgg agcatttatg
    48421 aagacattag aagagtcttt tgagttagct aaatctatgg ttgatatagg tactggtatg
    48481 aatagagata caatagggat tgtaacagat atggatgaac ctttaggttt tgcagtggga
    48541 aactctttag aagttataga ggcaattgag acattaaaag gaaatggacc taaagacctt
    48601 gttgagctat gtgaagtatt aggagcatat atgttggttt tatcaaaggt agcacatgat
    48661 tttgaagatg gtgttgaaaa gataagagaa tcaataaaat ctggtactgc tatacaaaaa
    48721 ctcaaagagt ttatagagaa tcaaggtggt aataaagatg tagtagatga ttattcttta
    48781 ttcaaaaaat caaagtataa atatccagtt aaatcaacta aatcaggtta tataagtaaa
    48841 attaaagctg aagatgttgg tgtatcagct atgattcttg gagcaggtag agaaactaaa
    48901 gatgatattt tagatttatc agcagggata attttagaaa agaaagtagg agattatgta
    48961 aatgaaggtg aagttttagc ttacatgtat tataatgatg aacaaaagct ttcattggca
    49021 aagggaagat ttattgattc ctactctatt gtagattcaa aaatagaaaa aaataaatta
    49081 atatatggta ttgtaactaa agaagagatt aaaaagtttt agaaaatttt agaaaagtga
    49141 ttataaaagg cctaacatgt caaaaataat gttaggtttt ttattttttg ataaactata
    49201 aattatacca aaaatatata ttttaaaaca ttttttacaa tataaataag tttattctac
    49261 aagatgattg aaaattaaag tatctagttt tataatagaa aatggataaa tatacataag
    49321 gagtagatta tattatgaac tttaaagaaa atagattgaa aatagcagta ttaataattg
    49381 ttattttgat tatcttagca ggtatatttg tgtttataca aataggtcct tatgataaaa
    49441 ataacaaaaa agatgtaatt atcgaagttc caagtggagc atctgttgga aaaatatctg
    49501 acatattata tgaaaataaa ttaataaaga atgaactatt atttaaactt ttggtaaagg
    49561 ttagcaataa agctccgtct ataaaatcag gaacatactt acttaatcaa tcgtattcaa
    49621 acaatgatat aataagtctt ttagtttcag gtaaaatata tcaggatggt ataaaagtga
    49681 ctattccaga gggagctaca tctaaagaaa ttatagcaat gttagtaagt aaaaatttag
    49741 gagataaagc tacttttgaa aatttaataa aaaaacctca agaattttat gataaatttc
    49801 catatttgaa ggaagatgga ataacctctt tagaagggtt cttgtatcca gaaacttatt
    49861 attttaattc aaagaaacaa tcagaagaag atattttaag cgaaatgtta aaagtatttg
    49921 acagtaaata cacggacaag tttaaaaaga aacaaaaaga attaaatatg actcttcaag
    49981 aagtaatgga aatggcatca ataattgaga aagaagctgt tcttgacaaa gacagaccta
    50041 taatagcaag tgtgttttat aatagactta aggtaggtat gcctcttcaa tcagatgcta
    50101 caatacaata tatatttgaa gagagaaaga aaattgtaac atatgatgat ttaaaaattg
    50161 attcaccata taatagttat aaaaataagg gattacctcc tacaccaata tcaaatcctg
    50221 gtataaaatc tattgaagca gcattatatc cagagaaaac agactattta tattttgtag
    50281 ctaagattga tggtggaaat aattatagta caaactatca agaccattta aaatacgtta
    50341 aagaatataa agaagcaagg gataaacaat caaaagatac aaaagcaaca aataaagaaa
    50401 atacaaaaaa ataaaccatg attataaaaa gtctaacagg gtaagaataa tgttgggctt
    50461 ttttattgaa aattgttatt cttagattta taataaagaa agtgtaaata tatataacaa
    50521 tatgaattta aaaaataata aattaatata aaacttgaat atttattatt ttagggagtg
    50581 tttttatgag taatatagtt aatgatttgg ttgaagatta tataagagtg acattaaaag
    50641 aaaaagaagg atttttaaaa gatttagaaa tttatgcaga ggaaaatagt gttcctataa
    50701 tacataaaga agtttcagat ttattaaaag tcttgttaaa ggttcaaaaa ccaaagagaa
    50761 ttttagaagt aggatgtgca attggttatt cttctatttt ttttgcaact attataggaa
    50821 aagatgcaga tataataact gttgagagaa atgaaaaaat gatagaaaaa gcaaaagaaa
    50881 acataaaatt agctggattt gacaataaca taactatact agaaggagat gcagaagaaa
    50941 aacttagtca agtccaaggt gaatttgacc ttatatttat agatgcagcc aaaggtcaat
    51001 ataagctatt ttttgattta gttatagata aattaaaaga tgggggactt ttagtatctg
    51061 ataatatttt gtataaaggt atggttgctc atgatgattt tgttgtaaga agaaaaaaga
    51121 ctatagttaa aagaatgaga aattatttag attatatatg taattgtgac tatttaagca
    51181 catcattggt accaataggt gatggtgtag cactaagtta taaagaaagt aaaagaggtg
    51241 atgtagatgg aattaaataa agtagaactt ttagctccag caggtgattt ggagagattg
    51301 aaaatagcta taacatatgg agcagatgcc gtttatatag gtggagaaat ttttggaatg
    51361 aggtctgcag cgaagaattt tagtaaggaa gatatggcag agggagtagc ttttgcacat
    51421 gaaagaggca agaaagtatt cgtaacagta aatataatac ctcataatga agattttcta
    51481 caattagaag attatttgtt ggaactagaa gagataggaa tagatgcagt tataatagct
    51541 gacccaggag tgcttagtgt cattaaaaaa gtaattccga atatggaaat acatttaagt
    51601 acacaagcaa atacaaccaa ttatctaagt gcaaacttct ggtacgagca tggaataaaa
    51661 agagttgtag tggcaagaga attatctttt gatgaaatat ctgagataag agcaaaaaca
    51721 cctttagata tggatataga agcgtttatg catggtgcta tgtgtatttc ttattctggc
    51781 agatgtttaa taagcaacta tatgactgga agagatgcaa acaaaggttc ttgtgctcaa
    51841 tcttgtagat ggcaatatca tttggtggaa gaaaaaagac ctggtgagta ttttccaata
    51901 tacgaagatg aaaggggtac attcttcttt aactcaaaag atttatgtat gatagagtat
    51961 ataccagagt taatcaaatc tggtataaca agtttaaaaa tagaaggtag aatgaagact
    52021 gcatactatg tagctactgt tgtaagagca tacagaatgg caatagatga attttacaga
    52081 gacccagaaa actggaagtt caatccaatg tggatggaag aactaaaaaa aggtagtcat
    52141 agacatttta catcaggttt ttacttgaat aaaccaacaa cagaagacca aaattatcaa
    52201 tcagcatcat atgttagaaa ctatgatttt ataggtatag ttagagaaac agaagatgaa
    52261 gatggtctta ttgttgttga gcaaagaaat aaaatgtgtg ttggtgatga aatagaagtt
    52321 atgggaccat ataaagaaac tatgtttact aaaattgaag aaatgtacaa tgaagaagga
    52381 gaagctatag aatcagctcc tcatcctaga caaatagtga agttaaagct atcagtaaaa
    52441 gttggtaaag attatatgct tagaaaagtt atagaagaaa aggttgaaga ataataaaaa
    52501 attgataaaa atagtattag ccccttagaa attgtcaata atgaaattat ctaaggggtg
    52561 atttcatgtc aaaaaagaag actccatttt tgaaaaaagt gggaaagaga agctggtgta
    52621 tatttactat aattttaata atttatagta ttttaattta taggctagtt gatatacaag
    52681 tattaaaagg taataaatac aaacaaagtg ttgaatcaca aagcgttgag aaagttgagt
    52741 taaatagtgg aagaggaata atctatgata gaaacaacaa gaagcttaca gatacaagta
    52801 aatctcaggt attaattgtt gaaaaagaaa aattaaataa taactataaa attttggagc
    52861 ttattaagaa agctactaag atgaatgatt tagatatata taaagctgta caagagcaat
    52921 tgacacgccc tataatacag attcagacta aaaatatcga taagagtatg aaaaaagaac
    52981 ttgagaaaaa tggaataatg gtagaagaaa aaactatgag gtacgcaaaa gatggtttat
    53041 tatcacatac aataggatat ataaaagaag atgataaatc aggtcaatca ggaattgaaa
    53101 agagtatgga tagtgtactt agaaattcaa atgaaaagta tataagtgct tttaaagctg
    53161 gagatgcagg aaatgaaaaa tctctaaaca tactaaaggg aagtgtaaaa actgttgata
    53221 ataaggataa agatagacat ctaaaaacta ctattgatta taacattcaa aaaaaattag
    53281 aacaaatact aaataaagaa gaaaatccta cagcagcaat aatctcggaa gcatctacag
    53341 gtgaaattct tgcaatgtgc tctagaccta attttgacca aaatgacata tcaaaaagtt
    53401 taaaaggaaa aaatggggaa tttgaaaata gagttataaa agcgacatat ccaccagggt
    53461 ctgtatttaa gatggtagtt ttattttctg cacttgaaaa tggtgttata gatgagaact
    53521 atacttacaa ctgtacaggt aagactaaag ttgggaatac taatgaaata ctgcgatgta
    53581 ataaaagaga tggtcatggt ttccaaaact taagacaagc tttttctaat tcatgcaatc
    53641 ctgcattttt agatatagct atgaaacttg gaaaagaaaa gatactcaaa tctgctgaaa
    53701 aattacattt atttgaaaag gttgatattg gtcttgatga agaaaaaatt agagaagctc
    53761 caaaaaacat atcaataaga aatttagcta taggtcaaga aaatatagaa tttacaccac
    53821 ttcaaataaa tcaaatgact caaataatag ctaataatgg aacattcaaa ccactatact
    53881 tatataaaag tcttgtggac aataatatga atacaataaa aacttataag tcttcaaaaa
    53941 aagaagaact tatttctcct tatgtgtgta cacaagttaa agaatatatg aagtctgtat
    54001 ctaggattgg tacagctaaa gacctaaaag atattgaagg tggttgtgga gttaaaactg
    54061 gtacagctca aagtagttta aataaaaaag ctatagacca cggatggata acaggatttt
    54121 atcctgaaga aagacctaag tatgtaataa ctgtgttagt agaaggaact caaaaaggaa
    54181 ataaatctgc aacacctata tttaaggaaa tatgtgaaag tataaaataa attatgtact
    54241 ataaaattta aggatatatc gtaactttga ttttagatag aaaactttgt ctaatgatgt
    54301 acgatatatc cttttaaaat atagtattaa ctttcttgaa caagctcttt ttctagtttt
    54361 ttaagagctt ttttttcgat tctagataca tatgaccttg atatatcgag tttttgtgca
    54421 atttctcttt gtgtcttata gccataagga gttaacccat atcttaactg gacaatttct
    54481 ctttctctag gagtaagaat tttgtttagt tgttcgtaaa gttttccaac ttgaactttt
    54541 agttcaactt catcaagaac atagttagcc tctgtgccaa gtatatctaa aagacttatt
    54601 tcattacaca ctactcttta tatgttattg gtattactgg tcttcatgta atttcaaatg
    54661 gaccattaat tcaaaagaat ctagtttttg ttctttagac ttataataaa ccgctttatc
    54721 aattacagat tttaggagtt tattttttcc aagggaatct gaatcatggt aaagtgataa
    54781 cacagtttta atatcttcta ttattttaga attgtctttt ttaacagtac tcaatctatt
    54841 ttttactgtc ttaattgaat ctttaatttc ttcagttctt gaacttatat tgttggacct
    54901 ttcaataaat gtatcttcat catatattcc tcgttctagt aaatcatata acttattttt
    54961 ttgcttgcct aattctttta actcagtttc taagcccttt aagactcgtt tttgaaattc
    55021 tatattacta tctttattat ttttatctaa atctaaatca gatgatttta attgatattt
    55081 ttttacagtg tcttccaaag attttaaaat ggcagcttca ataaattcaa atcgagaact
    55141 tttattgcaa ccaggatggt aacaaattat atagtcgtgg tctgcatatg gtctatatac
    55201 taatggtcta ccacaatttt tgcaaatcac tattcctgca agtggatttt ttatttgatt
    55261 accatagctg acatgaccat tttttttgag tatattttga gcttttttcc atgttatttc
    55321 acttattaaa ggttcatgct ttccttttgc ttcaatccat tcatctttag gtcttagttt
    55381 aactgttttt attttatttg gatttttaga ttttttgtag tccttttttt gccactgaat
    55441 gtagccacaa tataccttat tttttattat atttgtaatt gcagaattgt accaattagc
    55501 acctgtagca gttttaatgc ctaagttatt taagtatttt gatattttac tacaacccat
    55561 atcttcatta atatataagt caaagatagt cctaactaca tcagcatctt tatttggtac
    55621 aagtattctt tcttttctac cagttgttac agcatcatat ccaaatggag cagaggttcc
    55681 tatgaaattc ccttcttcaa ctgattttat tctacctctt tgcatccttc ttgatataag
    55741 ttttaattct tttcttgcca taaatgcttc aaattctgaa tactcctcat caaattcatc
    55801 tgttaggtcg tatgtttttc taggtgtgat gattttggtt ttactttctt tgaatgtttc
    55861 taatatgata ccttggtctt tcatgtctcc acgaccaagt ctgtctaagt ccattactaa
    55921 gactgcatca tatttatttt cttcaacttc ttttagaagt tcaagcattt tgggtctatg
    55981 tattatactt tcaccagaaa ctaattcttc ttttatttca attacatcta agttttgttc
    56041 ttttgctagt tttagtaggg ttgatttatg tctacttaaa gtttcaaatt cgccttgttt
    56101 ttctgcctct tcatcagcac gggattttct taagtatatg gcaacactca taataagtaa
    56161 tcacactcct taggtactat tatatagtaa atcaatagag tttaaaatat agaaaataag
    56221 catgtcaaaa gttaatttaa cttttaacat acttattttc tataatatta atgccttata
    56281 atcctttaat atcatttaga ttagtttttg catattcatt atccgggtta agttcaagcg
    56341 ccttattgta agattctcta gctttattaa attctgattt actcataaaa ataacacctc
    56401 ttaaattgta agcatcacta gcgtctattt tataagcttc attattttta tctagatatt
    56461 ctaaggattt atcaattgac tttaaagcct catcatatcg ttgtaactct atataaatat
    56521 atgattgtgt ataatatgca agtggatttt tatcatcaat ttctatagct tttttgatat
    56581 caatagcagc tttattataa tccttatctt catctttttt tgtttctgac ctagcgattt
    56641 tgacataatt agagctaaga gctcttttaa agtctttatg ccataataat ttatattcat
    56701 tatcttcgat tataaaatat ctatcaaaat ttgcagtatc ttctttattt tcagtgatat
    56761 actttatagt atcagtttct tttattttaa caagatctgt atactcttta ttagaatatt
    56821 tgtatttctc tactttattt tcttcaccaa gtttataatc ttttagggtt tgaagtttaa
    56881 ataaagtatc ttgatattct tcaaattttt ctagactgac actttcctta ctgtctttac
    56941 ttaataaatt atatgctact tcgtagtctt tgatttctat actatcaagg tactttttag
    57001 ctacttctgt agcactttct tttggagcac atccaaccat tgatatcata attaaaaatg
    57061 atactaatat tgctgttatt tttttactga ttatcataat ataatccccc ttatattgtc
    57121 tctcactaat tttattttat caccatattc taccaaagtc attaatttaa ggatgatatt
    57181 tttcattaat attatattaa gtaataataa tttttaaaat ttatggtaac attttcctga
    57241 aaagtattat ataatttagg tgaaaatatt taagagaagg agatattatg aaaattaaaa
    57301 aattattaac aatagggtta tctttatcta tatttattgc tagttgccct atatctgcaa
    57361 atgctcttga taaaattgaa tcaattaaag gtgcagataa atacgaaact gctggtataa
    57421 ttgcagacaa acaaaactat actacagcta tattaattaa tgcagacagt acaatggctg
    57481 atggattaag tgcaagtgga cttgcaggag ctataaacgc tccaattctt ttgactaaga
    57541 aaaataacat accaaatgct acacttaaaa gattagaaaa ggcaaaaaaa gtatatataa
    57601 ttggaggaga aaactctatt aataaatata ctgaaactgt tctaaaaggc aaaggaatag
    57661 agattaaaag acttcaaggt agtgatagaa ttaagacaag ctataatgtc gcaaaagaaa
    57721 taaattcaat taacaaagta aataaagtca tattgactaa tgcttttaaa ggagagcctg
    57781 atgcaatgag tgctgcacct gtagcagtta gagataaagc agctatagta ttaactgatg
    57841 gaaaaagtgt tccatttaat acaactggtg tagaaagtta tgtaataggt ggtacttcat
    57901 caatgaatga caaactagtt aagtatacta attcaactag attaggtggg acagatagat
    57961 atgatactaa caaaaagata ataaataaat tttatagtga agtaaaagaa ttttatatag
    58021 caagtggtac tgatttagtg tatgctcttg ttggttctac cgttgctaaa aataatgcta
    58081 ttgtgttagt tgataatgat agtaataaaa gtgtattgaa aagtacaact aaattaactg
    58141 ctataggaaa tttgagtgat agtatattac agcagtgttt aaatgtaaca aaaaatatag
    58201 gcgattctaa tactggaaga gaatatacag tagaagatgc tgctaatgca gtgaaaaaac
    58261 tattagatgt gaagaaattt tattacgaac ctaattattc agaagctgaa gatttaatat
    58321 ttctactaga taaaaatttt gatttttcag gaaaagagta ctatgtattt gcttacatta
    58381 aacagggtgc agagggtgat gttagatact gtgtagctaa aaatgatatg agcaaagttt
    58441 atacatatga tgttaatggt aatatgaaag tatgtaatcc agatgattat aaaaataaag
    58501 gaagtataac agaggaacaa gcaaaacaga tagcattaaa agaatgtgct aagagacata
    58561 aagtcagtat caataactta gtagttgata tgatagattt tagagatgat atatatagtg
    58621 gtaatgtcta tgctgttaaa atcaattcaa aaaatagtaa tggtactttt ggttggtttt
    58681 ttatagatat agaaactggg aaaatttata attaaaatta gaacttttaa acaagtgttt
    58741 ttaattatat aatttaccat aatatgttat aatattttta gcaagaagat ttaacttaca
    58801 atctatagag tggagttcat gtacaaaaga ttatcctccc aacgattcga agggaggtga
    58861 gttcatggat aactttttgt ttaatgtttt agctagttta acagctagtg tggtagttta
    58921 cttaatcagt aaactattca aaaaagcaaa aagccactct cgcacaaaga gtgacttacg
    58981 agttgaattt aaatttatat ttaaatccaa aaaataaact ctgtttatga tgaactccac
    59041 tctaacgcaa aatagattgt agttcttctt gcttttatta taccacaaaa cattataaat
    59101 aaaactgttg tttataaaaa aatgcaaagt aaaatttttt ataaacaatg ataaaaattt
    59161 tattatagag ctattaactt atgaaatatc tgtaaatgag tagatatttc ataagttaat
    59221 atttattgtt tgtataaaat atttggtaaa aataagtaag ttttatatgt tataataatt
    59281 gtagcaagaa taataatcta aagtggcaag catgtcagct ggtgttatat cagtttatat
    59341 ttatgataaa ataaaaatct cccaaacgcc aataaggatg atttaaaaaa ataatatttt
    59401 cacttaaaaa taatcactct ttataggagt aaattatttt cttgatttta ttgtactaca
    59461 aattggtaca gatatttaaa aataatatat tcataatatt ataaatagtt ttgcagtgag
    59521 cgatattttt gataaaatag ggcttaacag ttgaaacata aggcattgag ggtatatgat
    59581 aaatattatc atttgcacta ttcgtggttc actgcaaatt tgagagaatt gtatagatgt
    59641 aagtgttgga aatactcaat ttattttagg gttttatatt aactaattgg tatgtaaaga
    59701 agaatgtcta aagaattacc accatccttc tcgatatgtt ttatattaac taagtggtat
    59761 gtaaaggaca caaaatcttt atgttgtagg cggtggagca tgtgttttat attaactaag
    59821 tggtatgtaa agggtccaaa tacttttgat tgcagtgggt tcactcaagt tttatattaa
    59881 ctaagtggta tgtaaagatg tcagtcacta aagtaaaata ttgttgttct gccaagtttt
    59941 atattaacta agtggtatgt aaagtttttt acgtatggca ttatatgtgg cgttatttct
    60001 gttttatatt aactaagtgg tatgtaaagt ttagcgttct tgtcattcaa attcttttgt
    60061 ttcattttgt tttatattaa ctaagtggta tgtaaagaat ttatatatat aaacttctaa
    60121 actttcacga aaaggtttta tattaactaa gtggtatgta aagaaagaaa ttatgactag
    60181 ctttagcttt gaaacatacg agttttatat taactaagtg gtatgtaaag gtaaaaagag
    60241 aatgcaaatc ccaaggcaaa ctaaaaggtt ttatattaac taagtggtat gtaaaggata
    60301 gaatcggaga atggctgtct aatacatcaa aaagttttat attaactaag tggtatgtaa
    60361 agacagatct aatatcaaaa taaggttatg acttttaaaa gcatagccat atcaataaaa
    60421 atttaattat catttaaaaa ataaattttt atttaaagaa tacacataaa tatttccaga
    60481 cttaactctc ttaaaccatt ttcatatcct ttagtagata cttttgttat tttttaatct
    60541 ttagtaactt attctttagt gaatctctta ttttttctaa gctatttcaa gcttctcaaa
    60601 aaattctata tttatattca tcacatatat aatacaatta attcagtttt aattgccaat
    60661 atttagtttt tctgtatctg ataaaccaag aatataatca gtatataaac caaaaatttt
    60721 agcaaatatt attaacccat cgtctcttgt tggtctttca ccagactcta ttctattcat
    60781 aacacttgta tttatatttg ttttttcaag caattctttt tgagaacaat tcatattttc
    60841 cctagtatat ttaattcttt gatttacatc catacataat tacctcaaaa aatttctgtt
    60901 ttggaaatat tttattgaaa tatagcaatt aaggtgaata tatgaaaaag atacactatg
    60961 attttataaa aaagaagaca tacataaaat ttatacttac aaagtgttgc aaatgagtta
    61021 ggttttaaaa atgcatcaac gtattttaag tacaggaaag ggtaatattc aattagagtt
    61081 gatctgttac ctataaacta tctaagatac ttgattatga tatagaaaat ttttttacaa
    61141 attaaatttc taagatagaa atttaattaa gaggatgatg aggatgaata atttacaagt
    61201 aatataaagg aataataaga gaattttaaa tacatggcaa ctagcagata tatatgaaaa
    61261 tgatgtaaac aatatataaa ctaacttcaa tagaaataaa gagaatgtga attatttttt
    61321 attacaagtt gagtatttga aagaatttaa gaactaacct actaatagtc agttgatttc
    61381 aaaatattct agtcaattat acctttggac cgaaagatgt gcaaatagac actacaaagt
    61441 attagatact gataaaactt gagaacaatc tgacaattta gagaaaacat atttcaaggt
    61501 taagcgagag aaactaacct gtattaatag aaaatttaag ataaattgaa ggtttaagga
    61561 tacaaattaa tcaagcaata atatggcatt agaggcaaaa cagaagttaa aacaataaaa
    61621 gatgttgtta tattaaatac aacagattgg aaaaaagaaa caagtctatt aacagttaaa
    61681 atagctagag gtcaaggtga tttaagttat ataaaatatt ttactaatga gagctaagag
    61741 cttcttaaca agagttttgg tgtgtctctt gaaacaatgt taacaattaa taaaagacga
    61801 atggcagaag aaggcgtatg taagtttaaa agagataagt taaacaaact agatactata
    61861 taagaggata agaaacttat agaagaatat gttacttttg taaaggattt agctttaaaa
    61921 tatagaatat aaagtgattt taagtaaaaa ttgtaacaat taaataagta taagacaagt
    61981 ttatgagttc atattttata acaaggggtg atgttatgaa aatactacaa caatttaaac
    62041 catacaaata tgataaagaa aaaaatatag aatatgatga aaaaattata gctaatcaaa
    62101 acacagaagt ttatatagta tatccacgta tatctgatga agaaaatagg agaagatggg
    62161 aagagttcaa tgaagtagct aaagaagtag ctattaatat agctatgaag aaagttgaga
    62221 cagtagaaag ttaagagaat agagaagttg ctaatactta gcactttctc atagaagaaa
    62281 attggacaac tatttttaaa taattaggaa taaaaaagtt aaatcatatt tgaaaaaagg
    62341 cgataaaatt gttgagtatt gttattagta ataagaatgt attaactatg tattaaaaga
    62401 aattataagt ttttagtaaa tatagtattt aaggatatta aaactggcaa aaaataccat
    62461 ttagactatt aaataaaaaa gtgctggtca aagtaagcaa cacaataaat aaaaaaactt
    62521 atagaaatta taagataaaa agatgagatt tgaaatggtt gaagttaata taaaaattaa
    62581 aggtgaagta agtgaaataa ttgactcaat tagaggtata tttaatagct ttgatgaaga
    62641 gttaatatta gacataaaat cagagtaaga atataaaggt agatacgtag aaagttataa
    62701 gtaattcaag acttaaatta atttctagtt tttttaatgc aaaaatttaa taaatttcaa
    62761 aatataataa ttctgacatc taaaaagagc tattaaaaat gaataatatt gactattaag
    62821 atatgaatag tgtacatata ttaaattaag atatcaagta ggttaatttt atataatgat
    62881 ggggctcaaa ttgaagaggc gatataaaaa tgtattaata tatataaata taagaactat
    62941 aatacatatt aactgtaaaa ttaaatttat agagttatat ttaacattta atgaactgaa
    63001 aaatgaatta gcaaataatg aaaaaacaac agtaataaat gagaataaca aagtattttc
    63061 aggattagtg gatttttcta attgagattt aatcctagtt tgttcaattt cgatatttct
    63121 aatattatta atattatcaa tttatttgta ataattatca atttttgcga aacatttttg
    63181 ataatttata gaactttata tattttcctt gaagtatttt tcgcccttat tgtttggttt
    63241 ccaattttaa aactcataaa ctcccaataa attcatgtat aatatacctt aatttataat
    63301 atatttaaga gtttatttca gtaatttttc gaacgatttt gatatatttc atttatagtt
    63361 ttcaaaaact tatacaaaaa agagtgtttc atttttctaa acactctttt tataagaatt
    63421 tgaataataa ttttttaaaa attgataata tggttatttc tttttcaagt ttatagtttc
    63481 ctcatttcca ttccaagata taattagctt gtaactagat tctctatttg aataaagacc
    63541 tggtctttgt atttttattg ctttttcttg acctgcttct aaaatttcat tttttacaac
    63601 tacaactgca tcttcaccat ctataaattg ataggaataa ttaaattttt gttcaactac
    63661 atctttacta tttttatatt ttatttctaa ttttgagtgt ccttcagtag ttacaaattt
    63721 agctttccaa ttttctgatt ctccaataaa gacattttta tcatttttta tattaagtat
    63781 agctatcaca gagattatta aaactataag aatacctata aaaaattttt tcctcatatc
    63841 aatccctcct ttgaataatt ataacatgag aatagttatt caatactaat tttaaaaata
    63901 ttgtgaattt atattctgct acaatagaat gtctgttata acaaataaaa agtagggatt
    63961 aatatgaatt ataggttaaa agaatctgta acaactattt tatctttact cataatgaca
    64021 atactattac caacaaatgc aagtgctagt aaggtagaag attcatctat gaaagtaatg
    64081 tattcagaga aacaagtaac agacatggac aaattatacg atatggctaa aaatggaatt
    64141 actgatgtta aaagttccaa tgaaaaaggt ataatcaaaa atgcaagaac aggagagtcc
    64201 atatacgttg attctatatc aacaactcaa ttattagaag ttaaacaatc taaaaattta
    64261 acatcaaaga catattctaa gacagttttt tttgatacta atacaataaa gtctcttaga
    64321 aaagcaagta tatcagaaga tggatgggat aaaactggtg gtgtaaaagc atctggtaca
    64381 gttacatata caatatcaaa aggagatgga gcatttcgat atatttccgt tagtaaagtt
    64441 tctggaaact ggtctattgc agacggccag attcgtgtaa caaatagaag ggtgcatata
    64501 aatcaaactg gatttatttc taatgggcta ggaattaagc agcaacaaaa gaaagagcca
    64561 acatcaaatt ctttctcata taatgcacct tctagttgga aaccagtagg tagagattca
    64621 gttcaataca attgtgggtt tgaattaatt gcaacattag taagaggagg aagttcttgg
    64681 gcattcaatt tcattgttca accttaaaat attttaagtg aattttatta aaatcaaaga
    64741 tatacatata ctttaaaatt agagaatgta aattaatttg tgtttttaaa gataattcct
    64801 acgttatagt aacaattgct tatttactat taatatttct taatatatga attttatttt
    64861 aacaaattgt aaaaaatgta tattgggatg tttttaaata tttttggaaa ttatatatat
    64921 tataacaatt atagcaaatt tttagggtat aatttttaaa attatattct actatcaaaa
    64981 gatatgaata aatgattgta tatattatat caatttctat atttcatagt ccattttttc
    65041 atcatatttt cgcttgtcaa gaataatatc tttaagagtt aagcgtttga tgtaaatctg
    65101 gactttgttt ttgagacatt tttgaaatat ttattaaatc cttcgattat acttgtaata
    65161 tatattatag atattactta ttttagtaaa actaaaggct gatgctacaa cattctagtt
    65221 atttccaaaa gttttaattt ctgaagtata ctgtttacat tatttttaat ctattttatc
    65281 taaagtcgat aaggtttctt attcattaac tgacctatat acagatttaa aatcacttat
    65341 taattctttt gagtccttgt atgaaacata tttaaagtat ttcttatcta atgtattaaa
    65401 catttttgta ttacagaatg aggataactt gtagctattg tctctttgaa ataagtcatc
    65461 tgtgtttact cctaaaacta cttatatctg tagattttat aagttctcca tcttatataa
    65521 tttctttgat taattgtttt tttaaattat tcataaaaaa atctccgtta cgatatttga
    65581 ttatatttaa atcattgcca taaagaagac ttttattaac tttgaaaaac aaattatttt
    65641 acattactgg tgattagttg ctaccttctt ttgatattaa ttctattaga ttttatatag
    65701 ttatatatct ctttctaatt aagtaatata atattactgt tatagtagct actaatatta
    65761 ttgctattat tgtaatatct aatctttttg taaataagcc tattgctata tattcaaaac
    65821 ctgttacata tcgataaagt acttctagtt taatagttct ttttctatct atatttccat
    65881 attttgattc taatttatta aaatattttt cattacaaaa accaatttta atttcaatta
    65941 aagatattat tgtagttaat attataattc ccaatcccat aagtataaga taaatattcc
    66001 taaaattcat agaagatacc tcctttataa tataatcatc aactcatgtt gtattaattt
    66061 tcctaatcaa agtataacag taacacaagt ataaagagta tctaaaatat tacaaatatt
    66121 aaatgagaaa aagatggtaa gttaacccca ccatcttatt ttttatctac taatgaatga
    66181 tgctacaaaa gttagtataa aaaatgaaac aaacaatata atgaacttgt gtaatttact
    66241 tagttggaat gctttattac aaaataataa aattaatgct gaaacaattg caaaaagtag
    66301 atattttata atcattttat cacctattga tttctacaga ttgtaagtag tatttggtta
    66361 cacaagcacc ttctttatta taacgtattt tttaaattta aagatttttc cagatgttat
    66421 atttgactca aggtacattg taattactct aactataaca gtggcaagta ctgtcctata
    66481 ccaggaatag caccagccaa aagtcctgaa atccctatac cagcatcagt taaagttaat
    66541 gcaactcctt tagaaagata taaattaaaa cctattctag cccaaactat tttatttatt
    66601 tcagcttttc tataatataa ttcattttaa gtaatagtag tattaatatc gttcttctta
    66661 aggtttttaa ttagct
//
LOCUS       DACTZW010000011        61308 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.011, whole genome shotgun sequence.
ACCESSION   DACTZW010000011 DACTZW010000000
VERSION     DACTZW010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 61308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61308
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.011"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            279..734
                     /gene="smpB"
                     /locus_tag="JAM15_03855"
     CDS             279..734
                     /gene="smpB"
                     /locus_tag="JAM15_03855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HAT6797406.1"
                     /translation="MAGKKILATNKRARHEYFIEETYECGIELKGTEVKSIRQGKVNL
                     SDGFASVDNSEVFLKQVHISPYEQGNIFNVDSLRVRKLLLHKHEIRKLIGATTIKGYS
                     LIPLSLYLKNGKVKVEIALAKGKKLYDKRQDMAKKDAQRRIEREMTGKY"
     gene            892..1241
                     /gene="ssrA"
                     /locus_tag="JAM15_03860"
     tmRNA           892..1241
                     /gene="ssrA"
                     /locus_tag="JAM15_03860"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            1537..1752
                     /locus_tag="JAM15_03865"
     CDS             1537..1752
                     /locus_tag="JAM15_03865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3791 domain-containing protein"
                     /protein_id="HAT6797407.1"
                     /translation="MDERKLEFSIFCIEALAEKLNIDSEGVYKLLKHDTDILDNYIIP
                     CYEALHSQSKSYIVQDLIQVLKEKGVI"
     gene            1752..2231
                     /locus_tag="JAM15_03870"
     CDS             1752..2231
                     /locus_tag="JAM15_03870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012103284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3990 domain-containing protein"
                     /protein_id="HAT6797408.1"
                     /translation="MIVYHGSYCVVKTPNITFSRDSLDFGKGFYLTSIKTQALNWTER
                     FKKRGKKAYLNSYSLDIDELKKICNVKIFDSYNLEWLDFILECRNMSDVYMKYDVIIG
                     GIADDKIYNTIELYQDNLIEKDEALKRLKYYKPNEQICITNQNVIDKYLKFRCEEEV"
     gene            2237..2467
                     /locus_tag="JAM15_03875"
     CDS             2237..2467
                     /locus_tag="JAM15_03875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012103285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797409.1"
                     /translation="MEANKTLLQILYKKIILEFSRQTGKSLEESMDYLYTSETYKLIS
                     EGVSDMHCKGHIYLAQELMLENGLMYHKGYPR"
     gene            complement(2583..3749)
                     /locus_tag="JAM15_03880"
     CDS             complement(2583..3749)
                     /locus_tag="JAM15_03880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAT6797410.1"
                     /translation="MATKRANGEGSIGKYKDGWRSRIMIGYNEDGKPIRKEFYGKTQK
                     EVKDKLDAYKKQYYLSSDISDDKITLEHWFYNWLFEYRIKDLKPKSFERYESIYRNYI
                     KDTDLGNVKLKDLRVSHIQKYYNRLLDSNKSIPTIRQINTKLKTCLSEAEKQGLIQRN
                     YCTMVNIPVEKKENKLEILTLEQQKSFIKAIDGHKLEVLFLLALGTGLRLGELLGLKW
                     FDIDFKKSNLTVKRTLQRTYFIDKTGNRELKVLEQEPKTSNSYRTVPIPKDVLNKLKE
                     HKVNQNTDILKAGELYRNDNYVFCNELGIPIDDKRPLRNLKSILNSLNIEPIKFHGLR
                     KTYATRLFENDVPPKTVQVLMGHYDISITLNIYTQVMEDKKVEAVEKLDKIFSL"
     gene            complement(3739..4491)
                     /locus_tag="JAM15_03885"
     CDS             complement(3739..4491)
                     /locus_tag="JAM15_03885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797411.1"
                     /translation="MNKSYIPKYIYKFPTNLPHGDKKYTLTYIRRMISEFVYDMGNLE
                     NNPFTFPEVQTLLDGITVGGHKLSDQNQILNIKSSWDYVIKLSNKENLSLNKDTICSI
                     HKIVARDEALIVGDFRNGNIGIAGTTQYECIEATLLNELFVSDINIINKITNPLEKAI
                     VINLWLSYCQFFYDGNKRTARLTSNLILISNDIGVLSIPAKHKQEYNTLMLNFYETLE
                     ADEVIKFLLEKCITFFDGYNYKSYKELFKNGN"
     gene            complement(4583..5299)
                     /locus_tag="JAM15_03890"
     CDS             complement(4583..5299)
                     /locus_tag="JAM15_03890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAT6797412.1"
                     /translation="MIKKISTALSIPINRLIIDESDLDTSTNNYTNLKELDLVVKTFD
                     NYSAKLIGNNISKFRNINNISLKELSEKINCSENEIINYENGTKMPRIEILKKIALAT
                     YTKIEDLFGFPLEEIKIDNQTILYRNPQTGYIIDNFLIDFINKDINIDNTPVSYYIDK
                     SEFDLVIHILKNYGYDVKTDYKTKFEIADNADTIKPISLSFSDFKDFSKNLNWVINGL
                     VENFIQENSNGLIEDEDEEY"
     gene            5583..5777
                     /locus_tag="JAM15_03895"
     CDS             5583..5777
                     /locus_tag="JAM15_03895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003450825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6797413.1"
                     /translation="MKLKLKRIEKGIKQYELAEKVGISRYYLSSLERGKSKNPSNMLM
                     LKLAQELDTSVEELFFDKEE"
     gene            5781..6095
                     /locus_tag="JAM15_03900"
     CDS             5781..6095
                     /locus_tag="JAM15_03900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797414.1"
                     /translation="MANTNNLEVLKTLQATLNILVKQEQEAQERAKGYKEIQTYRRDK
                     AQLITCKEASKIYPIGESKFRQLCHSKNKGFPCIWIDNRVYIIKNKLDDWFIENANGI
                     KL"
     gene            6116..6859
                     /locus_tag="JAM15_03905"
     CDS             6116..6859
                     /locus_tag="JAM15_03905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797415.1"
                     /translation="MSNLGWIKLHRKIKESPLYKDCNSKQRDILINLLLSVNHKPNKW
                     VYGGKEYEVKSGQLITSLESIANMCSKDVSIQNVRTALKKFERYGFLTNESTNKNRLI
                     TIENWELYQSNEENQQTNQHAINKQLTTNKNVNNEKSKIYSEIIEKFNITCTELSKVK
                     KLTEARKKVINARIKEYDKETVLEIIHIVSKTSFLNGSNEKGWKANFDWIMSPNNFIK
                     ILEGNYQDKSINVKVDAEVYSPDDSQLKW"
     gene            6872..8206
                     /locus_tag="JAM15_03910"
     CDS             6872..8206
                     /locus_tag="JAM15_03910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAT6797416.1"
                     /translation="MDNMSNLVKNTEAEQSILGSILLDSRKIEEIEILISEDMFYHQE
                     HKHIFNSVKDIHKRDEPIDIITLTEDLKKKGLIDYVGGISYLTKLSTIVPTIGNVSHY
                     IEIVIEKYKNRNIIDKFNKFKLGEIDDNTLIYQLEKYINEVNQKLVKKDSSITAISER
                     AFEYINDEIEEGINIGIKFLDETIGGLYSGELITIAAKSGRGKTALALQIMRNVVFQG
                     KKVLFISGEMSDIQILFRNIASLTGISVVKMKNRNLNEEEIIKYINALSTLNQENNLY
                     INDSVNTISGIKREIKSIKPDVVIIDYLQILDYEGKEVGEAKFADLSRQIKKITLDFN
                     IPIIQLAQLNDELKDERPKGDRVMRSSKQIYMDSNSVIYIHRPTEKEALDYCKTMGIE
                     DIKELRCREKGFGANLSEIIVAKNRDGESGFRPYWYIGSLFSFRECKKTKEI"
     gene            8456..8731
                     /locus_tag="JAM15_03915"
     CDS             8456..8731
                     /locus_tag="JAM15_03915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797417.1"
                     /translation="MYDEIIEIYFDYWINKHMYRDILEKEEYYIEIWKKIRVFNELLK
                     KNLLEENEIHTLMELNDLFNSVIEFERELSYKFGFQAGAKFTVELLK"
     gene            9242..11533
                     /locus_tag="JAM15_03920"
     CDS             9242..11533
                     /locus_tag="JAM15_03920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020876172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAT6797418.1"
                     /translation="MTKKDMSERDICTKYITPALVEAGWDIKRQIREEVTFTDGRVIV
                     RGKVTTRGKKKRADYILYHKSNLPIAVVEAKDNKHSIGDGMQQAINYADILDLQFAYS
                     SNGDGFIEHDMKNGTEKEISLEKFPSPEELWNRYKGIKGITPAQEEIITEPYYFALGD
                     KIPRYYQIIAVNRTIEAVAKGQDRILLVMATGTGKTYTAFQIMYRLRSSGTKKKILFV
                     ADRNILVDQAIQNDFKPFQKVMIKVEDRKMDSSYEVFLALYQQLSGAEDLEVFKQFSP
                     DFFDLIIIDECHRGSAKDTSAWRKILDYFSSATQVGLTATPKETKEISNSAYFGEPIY
                     TYSLKQGIEDGFLAPYKVIRIGLDKDLEGYRPIKGKLDDYGNELEDREYNIKDFDKNL
                     IIDDRTKVVAKKVTEFLKKTDRFSKTIVFCIDIEHAERMRRALINENSDLVAENHKYV
                     MRITGDNKEGKAQLDNFIDEDSKYPTIVTTSKLLTTGVDCKTCKLIVLENNIASMTEF
                     KQIIGRGARLKPDYGKEYFTIIDFRNVSRLFADPDFNGEPVVIYEPEEGEDITPPEPD
                     NTYEDDEIKEEHTKYRVSDVKVKVISERVQYYDKDGKLITESLKDYSKKNIKEKFEDL
                     DAFLRKWNSEDKKQAIIDELVEHGALLDALREEIGNPDIDDFDLICHVAYDKKPLTRS
                     ERANNVKKRGYLYKYSDTAQKVLESLLEKYSSDKSIDLKDTKVLELKPFDEFGNPLKI
                     VKAFGGKKKYIEAIKELEKEIYV"
     gene            11635..13086
                     /locus_tag="JAM15_03925"
     CDS             11635..13086
                     /locus_tag="JAM15_03925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HAT6797419.1"
                     /translation="MSINNLIKRLQNIMRQDAGVDGDAQRIAQIVWILFLKVYDAKEE
                     LWEFHDDDYESIIPENLRWREWAVDEKDGQAMTGDALLSFVNDELFPTLKNLEIDETT
                     EKRSLIVKEVFEDAFNYMKDGTLLRQVINVIDEIDFTEAEERHSFNDIYETILKDLQS
                     AGKSGEFYSPRPTTSFIAQMLNPKIGDKCADFACGTGGFLISILELLIKQINTVEDKE
                     IVNKSLYGVEKKNLPHLLCITNLLLHDIDSPNIIHGNSLEKSVRDYKEEDRFDVIAMN
                     PPYGGVEQKNIQSNFPVELQTSETADLFVTTILYRLKQNGRCGIILPDNFLFGTENSQ
                     KALKEKLMNECNLHTIVKLPAGVFAPYTSITTNMLFFDKTGATEKIHYYDIPLPKGYK
                     SFSKTKPFRDIHLDEVRAWWNDRDNGNENAYVVTKDEVIANGYNLDFKNPNKLVEEHE
                     FTLEELLSYMDEKSKNISSLLEKIAMELEGVEE"
     gene            13086..13799
                     /locus_tag="JAM15_03930"
                     /pseudo
     CDS             13086..13799
                     /locus_tag="JAM15_03930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012323147.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
     gene            14678..14845
                     /locus_tag="JAM15_03935"
     CDS             14678..14845
                     /locus_tag="JAM15_03935"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797420.1"
                     /translation="MELKLVLQNIIDWVVNLDNTYIIQILTNIITSIGVVFGFIFSIV
                     TLRQSKQAQIE"
     gene            15651..17135
                     /locus_tag="JAM15_03940"
     CDS             15651..17135
                     /locus_tag="JAM15_03940"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797421.1"
                     /translation="MKRKELLLSFDSSVRFIFSHSALKEGWDNPNIFQICTLVNNKDT
                     FTKRKKIGRGLRLAVNQDGERITHQKDETVNVLTVIANESYDEFASALQLEIQEECGI
                     KFGHLEENSFQNIVICREDEDIQLGYEASKYIFDFMINKGYLSSKGNKKGKINEKLKR
                     CIVDEKVEIPLQYEGIKDEIINVIKRAIRRLPIGNNKDRVVIKPRKEILLSQEFTDLW
                     DRIKQKTIYRVESNDEKFIDICLKKMEDLKPRRSKINIDRVDIEIKCKGVEIEYKDTI
                     KQNLKQKTYKLPDLIRDIQDATMITRSTIIHILLKANKWDLFKLNPNQFIEKTIKIFN
                     SAKRELIVDEIKYEKVDDYYHKSQFEIEKDILIGYLQKNAIATSEENQKSLYNYILYD
                     SYIEKKFAEKLEKDEEVKVYVKLPSWFEIDTPIGGYNPDWAILMEENDIKKLYFVVET
                     KGSLDDDDLRKRERDKINCAKEHFKALESGIRYVVETDFDDIKE"
     gene            17496..19523
                     /locus_tag="JAM15_03945"
     CDS             17496..19523
                     /locus_tag="JAM15_03945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HAT6797422.1"
                     /translation="MSIDNNFNHIAFLWNIAESLRGTYKEEDYRKVMLPLIVIRRFDC
                     LLDDYDREIVKSVYKEYDFLPEEEKDELVIVDLKENHNIDLQFYNVSDFTWKKLLDDS
                     ENIKSNFEEYLNGFSNSVKEIIGKFKFKDEIAQLDKKDKLYAVLSKMYEVDLHINSVS
                     NNEMGYIYEEMLRRFTENSAAGEQYTPREVIRLCMEMLFMGKENFLTEEGKVISIADF
                     CCGTGGMLSIAEDYVEKVNPSAIVNVYGQELLDESFAICQADMIMKGQNPDNIRLGNT
                     LTQDRFSGEKIRFLISNPPFGVTWKDEEKKVKEEADLGFDGRFGAGTPRVSDGSLLFL
                     QNMISKMYDDEEGSRIAIIFNGSPLFTGDAGSGESNIRKWIIEKDLLEGIIALPTDMF
                     YNTGIATYIWVLTNKKEDKRKGKIQLVNASEYYQLMRKSLGNKRKEISLEQIEEIKEI
                     YERFEESENSKIFDNEGFGYRKVTIERPLKLSFRVNEEAIENVKNTTQFINLSVSKKK
                     DEEVKVKEEAEGRVKQDKLLKLLESFDSEFEYMKRDKFIKDLKSKSKLYDVALSAGLI
                     KAIVNAIGVRNEDAVVCKDAKGNIESDSSLKDTESIALKEDVYEYFEKEVKPHVEDAY
                     IDESSIDNIGYEIPFTRYFYKYEKLKSFDDIMKEVESLESEIALEIRKVLG"
     gene            19523..20890
                     /locus_tag="JAM15_03950"
     CDS             19523..20890
                     /locus_tag="JAM15_03950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HAT6797423.1"
                     /translation="MRYRYRDDEEMKDSGVEWIGKIPKDWEVKRIKHLFELKKDKSDE
                     ENPTVLSLTQKGLKIRDVSNNEGQLASTYVGYTKIEKNDFILNPMDLISGYTDKAEIE
                     GVISPAYTTFRSKNKVNINHDYYKRYFQMHYHHNFLFPWGEGVSFEHRWTLKNEVFLN
                     LPVITNRLEEQEKIANFLDEKTSQFEFIISKKEELIKKLEEAKKSLISEVVTGKVKVV
                     KTDDGYKLVKRSSEEMKDSGIEWLGEIPKDWEVKNFKYMFTLNKGLSITKADLKESGI
                     PCVNYGEIHSKYRFELKPSKHKLKYVDESYLKSNSISLLKYGDFVFCDTSEDIEGCGN
                     FTYLNENNKVFAGYHTIIARTLEQVNYRYMSYLFDSNDWRIQIRTKVSGVKVFSITQS
                     ILKGTKVILPDLLEQRNIAQYLDSKCKGIDSIIDKTKLQIDKLKEAKQSLISEAVTGK
                     IEILD"
     gene            20922..21374
                     /locus_tag="JAM15_03955"
     CDS             20922..21374
                     /locus_tag="JAM15_03955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797424.1"
                     /translation="MKLSRKNITMQVLSKFIENNLEKIENVETKANQIVFRTIDGDKK
                     IKIKTSKNYSEGEDPNTYLWTSFSSEELEEDYDYYTIICNEDIEKAVVFTKEELKQHY
                     VLETKKKKNREIDFELYPHFIGRRCIDARVHLYKEPIDITKYVNNYIF"
     gene            21408..21728
                     /locus_tag="JAM15_03960"
     CDS             21408..21728
                     /locus_tag="JAM15_03960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797425.1"
                     /translation="MLYVGDYIDMKTLNIRYKDGFKIEEDTRLYPINSDINDKIGVLV
                     EHRKLNATNRYLRYGIQKISGKCYFFDVRNSVISKTKESAYNTFICPYCRERMFIVSA
                     FERQ"
     gene            21804..22691
                     /locus_tag="JAM15_03965"
     CDS             21804..22691
                     /locus_tag="JAM15_03965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797426.1"
                     /translation="MKLRQNYYELEEFIHREIQDYVCKSAQEGFKLSIQSSYKLYKNL
                     HTNTIRADIQKERVNIVNAIPIYNTSQKNNKKYTPDIILYTDNNREIYCEISVYKSVN
                     TADYFDEWKVLGKTVIEIRKTEIMDMHLDGYRLSKDLIISYLYDPILDKARKQKISES
                     QKIIDKSNNIISKHKNLNKENNSKEKIREKEYKEFDDKVNYDIKKNLNNLNENNILIK
                     EYVDKRTDKQKRSDKRNGREPKKELVYFDVKANKEARIIYAVIMKNSKRAYRSIPAII
                     GKYLRDDGYKVGVAGKKRK"
     gene            22753..25734
                     /locus_tag="JAM15_03970"
     CDS             22753..25734
                     /locus_tag="JAM15_03970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HAT6797427.1"
                     /translation="MLPKEKHLEESIENHLVSIGYEQGHSQEFDLENCLFVEDLFRFL
                     EITQKELLDEFKYNRGSNYKKAFIDLINSNIKRRGLISVLRNGVEDIMMNGKFQLFYN
                     KPNLTTNKTAYENYKQNIFKITRQLKYSSKHNNTLDIVLSLNGFPVIVMELKNQFTNQ
                     NVYNAIKQFKQDRNPKETLFGFNQRVFVYFAVDTDEVYMTTELKGDKTFFLPFNKGNN
                     MGKGNPVVEGKEKTSYLWEEILTKDSLLDIIKRFYFIQEDDKKSKRAIFPRFHQLDAV
                     RKIVADLEVNKAGKNYLIQHSAGSGKTNTIAWTAHRLSSLHDEDNNAIFDSVIVVTDR
                     KVLDKQLQDAIYQLEHKNGLVVKIDDDKNSSDLADAIVNRAKIIITTIQKFQYALPKI
                     EQLEKRRYAVIIDEAHSSTSGENMNALKETLAGKTLEEAKIIDAENEKNEKSSIDKMN
                     DLIEKRTNLDHISFFAFTATPKNKTMQVFGRIGEDGLPHEFHLYSMKQAIEEGFILDV
                     LKNFMPVSVYYKVGKKIEDNPEFDKGEAKRAINKFISLNEHNIRQKVETIVDDFVDNR
                     SMWLEGRAKGMIVTASRLHAVKYKLAIDQYIKEKGYNMKSLVAFSDTVKDEDIEYTEV
                     GMNKEVAPDINDSNLPSIFEKSDFRLLIVAEKYQTGFDQPKLCAMYVDKKLDGVKTVQ
                     TLSRLNRTYPNKHTFILDFQNSVEDIQEAYKPYFEMTNIDKVTEPNVVNDLWYQLHEY
                     GIYTDEEVNDFAVLFYKDKRTNTQDAKMNSLIDKAVERYCYLDEEDEKSADEFKKKCQ
                     KYITFYNFLIQIYPIKNLNLLRLQVYLVALLRKLPKKGKERIDIDDILSLDYYKLQKL
                     GEDGKKGSDISLYNGEGELVGISETATSRVSEADEEYLEDIIQKINDVFGVGLTEEDR
                     IIIDQYEEMFKNDKSIMDIAKANSYEDLVSTFGKSYFKRGIVKTKNMNDRLVKEILTN
                     NNLQNYMIHYLAEKIYAEANR"
     gene            25752..26189
                     /locus_tag="JAM15_03975"
     CDS             25752..26189
                     /locus_tag="JAM15_03975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797428.1"
                     /translation="MTDKIIKPKNLFIYELKCDLIEDDERFVIKGKLDKEEINNLIFY
                     LQVEFRNILDNSILIPYDISNILTRLYGFEEVQNIEDISIDQTIELTDNIDENIYKID
                     QILENRSNLYVDGLYDMLEGIKLESVQDNPTVFEEEYVKLQNK"
     gene            26357..26692
                     /locus_tag="JAM15_03980"
     CDS             26357..26692
                     /locus_tag="JAM15_03980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797429.1"
                     /translation="MINLFKKEDLNLLLEYPKEVVENVDNVINILDESYGDNRKITDN
                     GGYVCIIEDIKEIEYLKSHILNGLIEEFSDVIYESEVDIYNSTLYLLSSDYSITIISK
                     NEETEHLLK"
     gene            26756..27217
                     /locus_tag="JAM15_03985"
     CDS             26756..27217
                     /locus_tag="JAM15_03985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HAT6797430.1"
                     /translation="MDKKKIPAKRVDIVSLKLVKESSVLYETRKISNPYDAYRLVKNF
                     LVDSYREKFVVVCLDTKNQPVSIEIVSIGTVNSAMVHPREVFKVVVLSNASKIICFHN
                     HPSGNTNFSKEDEVITKRLQKCGEILGIELVDHIVVGDDDKYFSFKENFKI"
     gene            27358..27651
                     /locus_tag="JAM15_03990"
     CDS             27358..27651
                     /locus_tag="JAM15_03990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HAT6797431.1"
                     /translation="MFKKENRYMTREIAENLPIEITILLWDLIDNLDIEKDYLQIFEI
                     NPIGLGVVEIVHRQEVPEYEASIYIQNDLIKYKLKIYAIDSIKYSTMMFSNEY"
     gene            27678..28274
                     /locus_tag="JAM15_03995"
     CDS             27678..28274
                     /locus_tag="JAM15_03995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797432.1"
                     /translation="MINNKSEIINKLFFNELKELIDKCNNIEDKTVYMIEKIFISIED
                     EEIKNYLIRNNCKLQELVNRYKKLELLNIDEAIFFAWYNLNINTISIDKASQYYYELT
                     TSNYIEVESHLVYTNEIDLREYAKDELDTMLDMEYHIDRLLDKDMIIDMWLNNTSKED
                     VIEEILMSDDIEDILDISPEYAFTTTSGIEYRYSEKEE"
     gene            28470..28685
                     /locus_tag="JAM15_04000"
     CDS             28470..28685
                     /locus_tag="JAM15_04000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mor transcription activator family protein"
                     /protein_id="HAT6797433.1"
                     /translation="MVDILGEEIVIKLYKYYRGQQITFPMKLYSNEYVERYIEKNYRT
                     KTLKDMCRELGYTEGWIKQLINKYKLK"
     gene            28914..30440
                     /locus_tag="JAM15_04005"
                     /pseudo
     CDS             28914..30440
                     /locus_tag="JAM15_04005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427584.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            30734..31072
                     /locus_tag="JAM15_04010"
     CDS             30734..31072
                     /locus_tag="JAM15_04010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797434.1"
                     /translation="MEQYSFSSELIDVMVNASNDLNRVYEKITSSGTFSGLQGTFDTL
                     YEYGLMLEDLLEVMDLSLLGGNETKEIIQNIAIDLKNISDEDNIADKALDLMGNIGEF
                     TYYIETNYSK"
     gene            31207..31452
                     /locus_tag="JAM15_04015"
     CDS             31207..31452
                     /locus_tag="JAM15_04015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797435.1"
                     /translation="MRSVTVEDGEERFAIEKIYVKSLKRYEVRICLYRDCKDRMNKLI
                     PRPVDISPDKLSTLILVGIKAGILDDDFKQELIKGLS"
     gene            31750..31941
                     /locus_tag="JAM15_04020"
     CDS             31750..31941
                     /locus_tag="JAM15_04020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797436.1"
                     /translation="MKYTLKYGLGQLKFDVKIRLEDILRLSSAGEDNDEVRLAERSRE
                     INDIIGKLYLRPSETKKKI"
     gene            32030..32942
                     /locus_tag="JAM15_04025"
                     /pseudo
     CDS             32030..32942
                     /locus_tag="JAM15_04025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427575.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            33123..33404
                     /locus_tag="JAM15_04030"
     CDS             33123..33404
                     /locus_tag="JAM15_04030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797437.1"
                     /translation="MELKTIRITFTVSSETSEDDLRKLCKDYMGDEYVVNDEGDFEIS
                     FYLNTVLGYNEVLYFMELIHMELEKSITLLGIRYKGIGGLQMKHILQEE"
     gene            33411..34538
                     /locus_tag="JAM15_04035"
                     /pseudo
     CDS             33411..34538
                     /locus_tag="JAM15_04035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427570.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            34668..35165
                     /locus_tag="JAM15_04040"
                     /pseudo
     CDS             34668..35165
                     /locus_tag="JAM15_04040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427563.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            35207..35644
                     /locus_tag="JAM15_04045"
     CDS             35207..35644
                     /locus_tag="JAM15_04045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797438.1"
                     /translation="MTIRINLDGENILENVDNKFYGLRARVDFDLDLLDEDVIDIMDR
                     ILTLDVNPSRMFITKGRVDIFYQPQKEISIESKLGYMKLINEFIDFIESQEIVEMKFL
                     GWNLNGDKIVESQANDSNISFSKEIFNPDTVYLDGLIEGYVNL"
     gene            35751..36666
                     /locus_tag="JAM15_04050"
                     /pseudo
     CDS             35751..36666
                     /locus_tag="JAM15_04050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            36933..38472
                     /locus_tag="JAM15_04055"
                     /pseudo
     CDS             36933..38472
                     /locus_tag="JAM15_04055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008680119.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            38605..39669
                     /locus_tag="JAM15_04060"
     CDS             38605..39669
                     /locus_tag="JAM15_04060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4297 domain-containing protein"
                     /protein_id="HAT6797439.1"
                     /translation="MSKIEYYMNLPYDLSGSMSKNRFRNELLWGLKKMYELYKTNEDF
                     VVVFDYRCDIEVHLENKFEFYQVKTQNNSGTYTINKLTDKKKGSKSVVGNLYSLKYDI
                     NMNEIDDVYVAIVSNAPLNDGKKTYNNSHEVKIKTIDSSAIEKIKLSIKNDLNIDEDI
                     NLENLFFIRIGLDLIEPQKTLIGETAIFFEDVFGRECSKVKSLYNVLYEEIYSKSAYE
                     LDINTYENIVSKKGINRDRMDIILKSYANNTDKSVELAKYSINEWCRNNFSRRLSLIK
                     SLTTIVSKLSESSILKDIENCILSYIYNNIDKLQVSDKELIEIISEIVEEKRPIEVSK
                     TDIEALILLTLKKYEEGVYE"
     gene            39662..41335
                     /locus_tag="JAM15_04065"
     CDS             39662..41335
                     /locus_tag="JAM15_04065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797440.1"
                     /translation="MNSLFVNSLYIFEYESKMAKKIDFKHGINILTSDEKSGNDVGKS
                     VLLKSIYHTLGADSIFDHMWNKITKTYILNVTIKNKTYYVYRRDNLFKIYNTNFKKIF
                     MTNNRDELSNYLSDLYSFKVMLPKRENEELELAPPVYSYLLNYIDQDHLDGSKFSSFN
                     SLTQFPNYKENVIYTHFGLFDEEYYKAIKELEILKSEEKNKKKEREVTLNMLNKIKSY
                     LGNLDAPESIEVLNIELNKTKEEYSNIVINLQKIKNNLMKIRNEKVDLELNIKEIELT
                     RRNEMKKLKVKNVCPSCSHEIEDIDSKFIINNQIEDLIILKDELESEIIKCNRVIEKK
                     EEEYQSLLDKLHEYESNMKINDDSISNVLKHKAYIDTKDDIVLDLEIIDKKIKEIQQT
                     IEPYDKKIKEYNSLKKKANAKYEELMKKAKKDFGLEEIDENKIKNIKNNFIARGSNRA
                     ITTIMWYLTLLAVKYEFNENAIKFPLILDSPNNVESDEIKEESLFKYIFKNTKTDTQL
                     ILSSLGFNEMQFSEFKFDNIIKLENSKYNLLNKEDYYNNIDILNKIFEN"
     gene            41440..42402
                     /locus_tag="JAM15_04070"
     CDS             41440..42402
                     /locus_tag="JAM15_04070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797441.1"
                     /translation="MKDRFNLKRKSIQSLMNKNVDVYSCKDCIDDFIESNFKIYRSYY
                     ISDDDILEIMDGTGEDYKDVIADMLPDKAHIKSGEFGEITATEIYKSNIQTTEIYIVD
                     KLSHTRKEDTKVAAHKTDILIIEKTSEGFIIHSSEVKTKITDSDFNPIEAMIEGVNDD
                     IVTRVAETLNWIQRKLKTEKKFDELKFIKQVIESIENQNVENEYNGAVFIDESKLDYE
                     INKNIYCDVKLSKSQKGKYDNELKSIGCVIDGDKIRFDSVNIDDINKLNINSRKRNSI
                     EKLYNKSQRKLEHIDDIKIQIVTFDDINKHCLDMYEKIIHVGRI"
     gene            42402..45113
                     /locus_tag="JAM15_04075"
     CDS             42402..45113
                     /locus_tag="JAM15_04075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797442.1"
                     /translation="MSINNNINKIRNLDIQLAKYDCISRMSAKETSKHYMRLYFKFIK
                     LLELYEDSSLNINNGEYLNLANDLIIFSKYDMSSRFKGIDEERNLVYIAVIYYILGYR
                     FECNLILDILDMHDIENEYLKIIIYLIRNKYYKCDVLSCIKKYYIEDESNLSLIIKTL
                     YEKELVCDTKDQTYIQIIIAILRNIQNNGFYRVISKKSKLDINIWRKFVQQSIKYDQI
                     IYDLPKYHYDLLNDELLNIKHGYINMPTNYSKIEVIKIVIFNYLHTYQDKKIAYIHVD
                     KDDRAINAIKEYFTEYSTRIEFIEIDSINNYSEIATDNNFIIIDDFSNVSNKYYGTRF
                     EIMISLALKLEKRLLVLNNNYLKMDSNQLENINYNEDINRYSNIVNYYFKDGKNKELE
                     IEYEKERFVTESYLLNKEINNKINLKGIKLNSAGDKSLLSAINLISKGYKVSIFIPQK
                     NSAKSGINKICIKLLNLIDRLNGKILYDKNCIDDSNLLDRAELLLGRESIYMKLFRLG
                     VIVIHSDMPQEVIEYMRYFIQCGKYKIIIGDKILTKNLSKYTDVLIINSIRINIDKSW
                     SIIDDRLLLDLINDFSDQINKKHIIISNYKQKDIYKTKIKNIKKGLILNSFISQSLHN
                     IELFKLNYEEEINNILDSIEYNICEYILYDYSNEFLDNLIYTNNQVDFIKEGQFVKLL
                     NKKIDKLKSLSKDKIAVIYKSKANLSCLDMYIDLKNKYINFDDIELINYIFYNYIVVN
                     KEYVNIISNIEYIYKLNINEDGIYNIILHWISEYDYNDIDTLTKINNLEIIFTVIEKV
                     VRGLFVEMLCKLQNICKINDSTKLHNKLQYIKDILYNGLKENIFLEKLNYKLLDRRLT
                     KKINLYMKKNAELYESRVETILLNIREYVDLDEFELFIIDKLIQKIK"
     gene            45727..45968
                     /locus_tag="JAM15_04080"
                     /pseudo
     CDS             45727..45968
                     /locus_tag="JAM15_04080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433783.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator"
     gene            45962..47355
                     /locus_tag="JAM15_04085"
                     /pseudo
     CDS             45962..47355
                     /locus_tag="JAM15_04085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428529.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
     gene            47615..47872
                     /locus_tag="JAM15_04090"
     CDS             47615..47872
                     /locus_tag="JAM15_04090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797443.1"
                     /translation="MSKKISESIENSGLRVAENKSDGSFVLSLGNLEYTKEQSSQVLH
                     YSMTKDKKGTKEVLSIQCVKDFSYNEKLSEDDKFIMAIYNI"
     gene            47877..48056
                     /locus_tag="JAM15_04095"
     CDS             47877..48056
                     /locus_tag="JAM15_04095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797444.1"
                     /translation="MIHVEISEKEFFRKIEEVFDKGEGNIDVDNLGDIKIQVKKFDDK
                     TRSLELKLIKEFKLK"
     gene            48068..48316
                     /locus_tag="JAM15_04100"
     CDS             48068..48316
                     /locus_tag="JAM15_04100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="HAT6797445.1"
                     /translation="MRKYKAILLTLITSIVAIIGFIIYNNYFRKWNEAEKYINKYMTY
                     QGVSGDDIERITKEKYTKENYDGILYKSFYKNYPSYEY"
     gene            48496..51051
                     /locus_tag="JAM15_04105"
     CDS             48496..51051
                     /locus_tag="JAM15_04105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAT6797446.1"
                     /translation="MGIYLKMSLAYLKKNKLRTLLLIIGVMLGVMLIFGPSVIKDSQN
                     ENNVVAIHELYSGYHVEFSDLTLDDAKKLETDEKVSKGNSVQNLGRISDKKGNSFILT
                     SSNEEYLKSRYNKIIEGRLPKNNNEIVLEKKALEAMNLSEGVGSTLNLTIKKNYKDTN
                     GSNQLFSINKEFKIVGVMEKPKGYYDVVWQYEAVTYGNDETNNIIPNDAISYNSILSF
                     KSGWRNIEGECDYLMKKYKLGQKSFLPNVPLVRELRYVEDDKNDPNVFKRNVLITTVS
                     IIFIFNIFNITLNQSVKEMGLLRLMGAKKRNVRCMIIYQALIITIIGILLGLVAGVTY
                     SYIGISNYNEVLYSEAGLNPKLYINNEIVIKAILVGIISVFISCIIPTFKIGKISPIE
                     SIINTDKIKNHRSRLGIDRLVSKIFGFYGFMGLKNIGRNKVRAAISMLSIALGGYIFI
                     TTFSSMQEEVNSKIEDMQNRYNITMQFGVNADPQISKYTDSDVENIEKIKGVKSIYKI
                     QITNGMFTFNNKDINKEFTTYNGVEKKEIMEDKLVLKLYDDDYIDEKLNDFVEKGRLD
                     DIKKDTDGYPNVAVYNYFYDIVDDHTIKPIFKELNMGDIITVKIPVEENNTIVYKEKK
                     VRVAVILKDEWIAMGDGDFMPDLEIITSNIHSKNITGEQKYTQLGINLEDPYDEIVNN
                     EIQKISRSIPGSLFNSRLSYHEMSESIYKSYIKSQIAIIALVLIIASINIFCTIRTNL
                     LIRKKEISTLRALGVSLKNMKKMLIYEALAYAVFSFIIAMIPSFINLVKFTNWNNDAY
                     INYGVENFMSFTFPIKESLLFFAISVFVCLIAVVVSNRDFESMNIIEGIKENE"
     gene            51068..51730
                     /locus_tag="JAM15_04110"
     CDS             51068..51730
                     /locus_tag="JAM15_04110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6797447.1"
                     /translation="MKMLKVIDIKKIYGKGENEIKAVDGITLEIEPHKFSAIIGQSGS
                     GKSTLLHCMAGLDKPTLGNVFMDNLDLYTLSDEKLSNLRSKEFGFIFQNYNLIPVINV
                     YDNIVLPILIAKGKIDNNYINDLITKLGLESQINKFPNELSGGQQQRVAIARSLANKP
                     SIIFADEPTGNLDSKTTNEVMNLLKYCVNEYKQTLVMITHNDEIAKMADCIITISDGK
                     VI"
     gene            complement(52742..53314)
                     /locus_tag="JAM15_04115"
     CDS             complement(52742..53314)
                     /locus_tag="JAM15_04115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class B sortase"
                     /protein_id="HAT6797448.1"
                     /translation="MKKLVKILINIICIIALTFSSLSIYIKLSEYKKAAEVYTELREN
                     TINNSKHQELYDKNNDYRFWLKINNVNIDYPVVQGYNNDFYLTHDFYKNYLPLGSIFM
                     DYRNNFENDKSLIVYGHYMKNKTMFGQLENYTDEVFFKENNLVEINYKVQTYTYEIFS
                     VYTADLINRDYLSIHFNNNYEFKDSLNYIT"
     gene            53583..56915
                     /locus_tag="JAM15_04120"
     CDS             53583..56915
                     /locus_tag="JAM15_04120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797449.1"
                     /translation="MQQKCKKKALSMILSISMGLGSVASFNASNTFADTIEESTNAGN
                     AEGDTNAGNAGEDANAGNAGEDANAGNAGEDANAGNAGEDANAGNAEEDANAGNAEGD
                     ANAGNAEGDANAGNAEGDANAGNAEEDMNALVVEEATAEDPTSVGDFKISGGEINVDF
                     KFASGVLTILSGKQMTIQNNNPNTPTTHRIVIPKDVKAELIFDGVNIKTASNSPFTLT
                     PDKDGGAYAHVILQDGSENKLESGDLYYPGMRAGKGTTLIIDDSVVNRDIEGEFIVPE
                     GGKIPRDVTLENGDKLKKGDRLTLLDSNNRGSLKVVGNYYSAGIGGGNTESGGNIIIN
                     GGAITAIGQESSRNTGYGAGIGGGGNGSGGDITINGGTITAKGAYHGAGIGGGYYTTT
                     KNALSPSVVDPSTGSGYSGNITINGGLSYSYGGAHGSAFGDGCVNPGTNRGYRILVTG
                     GTILPYMTGVGDWIFDLSATTGDVIVTGGSLKATTFKSLGGAVAYGDLEKKTKVFMNK
                     ISLKYLGQDKVSTTLVDDFKMLIDGKIYPYGAPSYTDDQGVLYLWFSDQFKGSEVSVN
                     LVVIDKITGGNIKPDDFYVKDIGSGSQFLKQYEEFTIDDTPPYLIIKRYDGLPFEEDV
                     EKSFLDWILKDGGIPIITPKGEKLTDKKFMTISSQRLNEETMEPDTNLGSDDLTKQVD
                     AGKYQLSITSTQFSNVYPFNEAYWGHRAYYKAEIIPADTETSLVVEESKAKTDVFKPT
                     DTFTLNVTISPDKKEGPDCASPRGYVQFYINGKEYKDPVELKTHNKGSESHNYSTASI
                     EWRPLDSNHHIFTTEQTITVKYIGDDINYIEGSEDEKKLKLDMTNVDVDGDGIPDINI
                     DTDGDGRPDINIDTSGDWKPDINIDTDNTGEWKPSTEGENGDGIWKPDKNIDTNGDGN
                     PDTDYNRPAIDTDNDGVDDYWKPDKNVDTGSGGYDTGNPNLNKPDPDNGGNSKPDPDN
                     GGNSKPDPDNGGNSKPDIDTDGDGKPNINIDTDGDGKPDINIDTDGDGKPDINIDTDG
                     DGKPDINIDTDGDGKPDVNIDIDGDGKPDINIDTDESLDSNVGQNVQTGDQSNIMLDL
                     ALMFISLFFLIKNLTNKYLRRK"
     gene            57676..58638
                     /locus_tag="JAM15_04125"
     CDS             57676..58638
                     /locus_tag="JAM15_04125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017561613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HAT6797450.1"
                     /translation="MAKIDNMMSILWMLNSDKKITAKQIAEKLEINIRTVYRYIDVLS
                     ASGVPIISDTGHNGGYSLLNNFTKAPLFFDIEEQKSLLHAALFAKKEGYFLDEALDKA
                     ILKLKMYSNQKQEDILTNHLIALEVIKPIGKVSIESVLKKLENSILKELSVEINYHAG
                     RKVRSKYRIINPYGIVHWNNNWYVVAFCNMRNEVRSFRVDRISEIIETSNTFNRPTEF
                     SASEFFIKGIVPEIKDEQNIIQLVVEGSIDSLDSLSQHWFLGHYLKERTPNKIIFMIE
                     EEVICKYIPNILLPYRKTIQVIEPLSLRKKIIEDLLELIEYYQI"
     gene            58717..59346
                     /locus_tag="JAM15_04130"
     CDS             58717..59346
                     /locus_tag="JAM15_04130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HAT6797451.1"
                     /translation="MKNRKVYMYVFDTMSDWEVAYLTAELNTGRYFKKGLKLLKVITV
                     GIDKNPIITMGGLKVLPEITVDEFNMESKDLLILPGGNTWLSMNHEIILEKAKEALIQ
                     DSIVAAICGATLGLAKKGLLDFRNHTSNDLEFLKMVIPNYSGEKYYKTESVVSDENLV
                     TASGIAPLEFTFQVLKLLDVFESEALNSWLNLYKTHDSKYFFELMNCNK"
     gene            60177..60590
                     /locus_tag="JAM15_04135"
     CDS             60177..60590
                     /locus_tag="JAM15_04135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797452.1"
                     /translation="MSKSELGVKTNLVSELLMISYFFIDSLLKKFIFKEGNICITFII
                     LFAFWACDFMYNKKYNDLVDEASKLMLLKVDHIASKIMLYSIFLIAVFFSANYTRGLD
                     ISNLDIGVILLAILFIQSLSKLILYIHFDRKGICN"
     gene            60658..61074
                     /locus_tag="JAM15_04140"
     CDS             60658..61074
                     /locus_tag="JAM15_04140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797453.1"
                     /translation="MSKSETGVRSKLILELLVITYFFIAVLATKYIFKGPSTASLPGL
                     SWLIVFGCYSIYNKKYNDLVDESSEFILSKVNKIAIKIMIYSIVIISIFFATPYTSNI
                     NISNIDTGIILIAVLFIQSLSKLVLYIYFDKRGICN"
     gene            61081..61287
                     /locus_tag="JAM15_04145"
     CDS             61081..61287
                     /locus_tag="JAM15_04145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6797454.1"
                     /translation="MLMKTKIKEYREKLLMTQNELAKLVGVRRETIVHLENGKYNPSL
                     KLAMDIAKVFDTTVENLFEFIEEE"
BASE COUNT        25806 a         5841 c        10343 g        19318 t
ORIGIN      
        1 tataatatgt aatattttgt tttgaaattt ataaattagt attactggtt agagttagtt
       61 tagtattaag tatattcgaa gtagtttttt agctattttc atacatttat attacttaat
      121 tatatatagc ctaactaact taatatatca gtgaaatatt gactaaaatg cctaaatatg
      181 ttatcataca agttagtcaa ataatttggc aacattaaat atttagtaaa tttctaacat
      241 ttatggaata aatttctagc aaagaaggtg agatttatat ggctggtaaa aaaatattag
      301 caacaaacaa aagagcaaga catgaatatt ttatagaaga aacttatgaa tgtggaattg
      361 aattaaaagg aacagaagta aaatcaataa gacaaggcaa agttaaccta agtgatggat
      421 ttgcatctgt agataatagt gaagtatttt taaaacaagt tcatataagt ccatatgagc
      481 aaggaaatat attcaatgtt gattctttaa gagttagaaa actattactt cataagcatg
      541 aaataagaaa acttattgga gcaactacta taaaggggta ttcacttata ccacttagtt
      601 tgtatctaaa aaacggtaaa gttaaagtag agattgcctt agcaaaaggt aaaaaactat
      661 atgataaacg tcaagatatg gctaagaaag atgcacaaag acgtatagaa agagaaatga
      721 caggtaagta ttaaactaga taaaactgta ttttttagaa taaaattctt tattatctag
      781 aacataacat tgatttttat tcttaaaagt attatattat atatacatta aaaatttaat
      841 aaaaatggtg ataaagtttg cgaaaagtct actggactat aaactactca agggggcgta
      901 aaggtttcga cgtgggtttg gaacttgagg ctgcatgtcg tgttactctg ggtcacgtaa
      961 aaactgggga actttaaaat aaacgcagac gataatttcg cgatagcagc ctagttgctg
     1021 ctcgtccctc ttagtcctcc tgccgactaa gactggacgt cattatgcag ggaactactt
     1081 taggggtgtc tcgacttgaa gtagattaat tgggactggc taagcataga gcctgccact
     1141 tggcgttatg tgaggtgaga tattagtgaa gttggctaag catgtagatg cagcaaggaa
     1201 aagatttgcg gacaggggtt cgactcccct cgtctccacc aattttgaaa aaagaatgat
     1261 gaaatacttg aaaatactag tctttattga ctggtatttt ttgttttggt gataaaatcc
     1321 accaaccgta ccccaaccac agaaaatgag gtttttttgt aggtatattg gggtgcattt
     1381 agggtgtata aaaagccttt atttattatg atattaggta acatagaatt ttaatatcta
     1441 ctttatgata taatattttt ataaatgtaa aacagttgaa gttgttaatt aataaaaata
     1501 tatattatat aagtttgata ggagttgagg tttgtaatgg atgaaagaaa actagaattt
     1561 tctatttttt gcattgaagc tttagcagaa aagttgaata tagattcaga aggagtttat
     1621 aaacttctta aacatgatac tgatatttta gataactata taataccttg ctatgaagca
     1681 ctacattctc aaagtaaaag ttatatagtg caagatttaa tacaagtgct taaagaaaag
     1741 ggtgtgatat aatgattgta tatcatggtt catactgtgt ggtaaaaacg cctaatatta
     1801 ccttttcaag agattcttta gattttggaa aaggattcta tttaactagt ataaaaacac
     1861 aggcacttaa ctggacagaa cgttttaaga aaaggggtaa aaaagcatat ttaaatagct
     1921 attctttaga tattgatgaa ttaaaaaaaa tttgtaatgt aaaaatattc gatagttata
     1981 atttagaatg gcttgacttt atattagaat gtagaaatat gagtgatgta tatatgaaat
     2041 atgatgttat aataggtgga attgctgatg ataagattta caatacaata gaactgtatc
     2101 aagataatct tattgaaaaa gatgaagctt taaaaagatt aaaatactat aaaccaaatg
     2161 aacaaatatg tataaccaat caaaatgtaa tagataaata tttaaagttt agatgtgaag
     2221 aggaggtata gtgcttatgg aagcaaataa aacattatta cagatactat ataaaaaaat
     2281 tatattagaa ttttctaggc agacaggcaa gagtttggaa gaaagtatgg attatttata
     2341 tacttctgaa acatataaac ttataagtga gggtgtatca gatatgcact gtaagggtca
     2401 tatatacttg gctcaagaat taatgttaga aaatggatta atgtaccata aaggctatcc
     2461 aagataaata attaaaacta gatacgaaat aaggatacaa gataatataa aattaatttg
     2521 tatccttatt ttgattttgt aattaactat atgaaatcac aatatttata tgtatttgat
     2581 ttttacaatg aaaatatttt atccaacttt tctacagctt caaccttctt atcttccata
     2641 acttgagtat atatatttaa agttattgat atatcataat gacccattaa aacttgtaca
     2701 gttttaggag ggacatcatt ctcaaaaagt ctagttgcat aagtttttct aagaccatga
     2761 aactttatag gctctatatt taagctattt aatatggact ttaaattcct taaaggtctt
     2821 ttatcatcta tagggatacc caattcattg caaaatacat aattatcatt tctatataat
     2881 tctccagcct ttaatatatc tgtattttga tttactttat gttctttcaa tttatttaag
     2941 acatcctttg gaataggtac agttctgtaa gaatttgatg tctttggctc ttgctccaat
     3001 actttaagct ctctatttcc agttttatct ataaaatatg ttctttgaag agttctttta
     3061 actgttaaat tggacttttt aaaatcaata tcaaaccatt taagtcctaa taattctcct
     3121 aatctaagtc cagtaccaag agcaagtaaa aataatacct ctaatttatg tccatctata
     3181 gcttttataa aactcttttg ttgttcaaga gtcaatattt caagcttatt ttcctttttc
     3241 tcaactggta tatttaccat agtacaataa ttacgttgta taagaccttg tttttcagct
     3301 tccgataagc aggttttcag tttagtgttt atttgtctta tagtaggtat acttttattg
     3361 gaatcaagca atctattgta atatttttgt atgtgagata ctcttaagtc ttttaattta
     3421 acattaccta aatcagtatc tttaatataa ttacgataga tgctttcata tctttcaaat
     3481 gacttaggtt ttaaatcttt tattctatat tcaaacaacc aattgtaaaa ccaatgctct
     3541 aaagttattt tatcatctga aatatcagag cttaaataat attgtttttt ataagcatct
     3601 aatttatctt taacttcctt ttgagtttta ccataaaatt cttttcttat tggtttacca
     3661 tcttcattat aaccaatcat tatacgagaa cgccaaccat ctttatattt tccgatagag
     3721 ccttctccat tagctctttt agttgccatt tttaaacagc tccttatatg atttatagtt
     3781 atatccatca aagaatgtaa tacatttctc taataagaat tttataactt catcagcttc
     3841 tagtgtttca tagaagttta gcattaatgt gttgtattct tgtttatgtt tagctggtat
     3901 tgatagaact cctatatcat tacttataag tattaggttt gaggtaagtc tagcagttct
     3961 tttgttgcca tcatagaaga attggcaata ggacaaccat aaatttatta ctatagcctt
     4021 ttctaagggg ttagttattt tatttatgat atttatgtcg cttacaaata actcatttaa
     4081 tagagtggct tctatgcatt catattgagt ggtaccagct atacctatat taccatttct
     4141 gaaatctcca acgattagag cttcatctct tgcaactatt ttatgtatag agcaaattgt
     4201 atctttattt aaagataagt tttctttgtt acttaatttt attacataat cccatgatga
     4261 ttttatattt agtatttgat tttggtcact taatttatgt ccacctactg ttataccatc
     4321 aagtaatgtt tgtacttctg ggaatgtgaa ggggttattt tctaggttac ccatatcata
     4381 tacaaattca cttatcattc ttctaatgta tgttaaagta tattttttat ctccatgagg
     4441 tagattagta gggaatttat atatgtattt tggtatatat gatttattca tgattgtagc
     4501 tcctttcata tctaattttt atttattaac tatgaatgta taaaagttaa taggtaaact
     4561 catattttga aaatgtgcaa tattaatatt cttcatcctc atcttcaata agaccattag
     4621 agttttcttg tataaaattt tcaacaagac catttatcac ccaatttaga tttttggaga
     4681 agtctttgaa gtcagagaag cttaagctaa ttggttttat tgtatctgca ttatctgcaa
     4741 tttcaaactt tgtcttataa tctgttttta catcataacc ataatttttt aatatatgaa
     4801 ttactaaatc aaattctgac ttatctatat aataggaaac tggagtatta tctatgttaa
     4861 tatctttatt tataaaatcg ataagaaagt tatctataat atatccagtc tggggatttc
     4921 tatagaggat tgtttggtta tctattttta tctcctctaa tggaaatcca aataagtctt
     4981 caatcttagt ataagtagca agtgctattt tttttaatat ttcaattcta ggcatttttg
     5041 ttccattctc ataatttata atttcattct cagaacaatt tattttttct gagagttctt
     5101 tgagagatat attatttata tttctaaatt tgcttatatt atttccgatg agttttgctg
     5161 agtaattatc aaatgttttt acaactaaat ccaattcttt taaattagta taattatttg
     5221 ttgaagtatc taaatcactt tcatcaataa taagcctatt tataggaatt gataatgcag
     5281 tagatatttt ttttatcata tctaaactag gttttctttg gccttgctca tatttagcta
     5341 cagcataaac tgaacaacca atcttattag ctaactcatc ccttgacata tttatagatt
     5401 ttctatattg tttaatcttt tttccaattg tattatttat cataatttca cctcaaatac
     5461 attatagcac taaatgggtc tattgataca cttaaatata ttgacaatac accgaatggg
     5521 tgttagaata ttttatagaa atgagaatac acaaaatggg tatgaaagaa aggaggaaat
     5581 caatgaaact caaattaaaa agaattgaaa aaggtataaa gcaatatgaa ttagctgaaa
     5641 aagttggcat ctcaagatat tatttatctt ctttagaaag aggtaaatca aaaaatccaa
     5701 gtaatatgtt gatgttaaaa ttggctcaag aactagatac aagtgtagaa gaattatttt
     5761 ttgataagga ggaatgatgt atggcaaata caaataatct agaagttctt aaaacactac
     5821 aagctacatt gaatatactt gtcaaacaag aacaagaagc acaagaaagg gcaaaagggt
     5881 acaaggagat acagacatat agaagagata aagctcaact tatcacatgt aaagaagctt
     5941 ctaaaattta tcccataggg gaatcaaaat ttagacagtt atgtcattct aaaaataaag
     6001 gatttccctg tatatggata gataatagag tgtatataat aaaaaataaa ctagatgatt
     6061 ggtttattga aaatgcaaat ggcataaaat tataggttca agtgggtgat agtacttgag
     6121 taatctaggt tggataaagc ttcatagaaa gataaaagaa agcccactat ataaagattg
     6181 taattccaaa caaagagata tactcataaa cctattactg tcagttaatc ataagcctaa
     6241 taaatgggtt tatggaggta aagaatatga agttaaatcc ggacagttaa taacatcttt
     6301 ggaaagtata gcaaatatgt gttcaaaaga tgtaagtatt cagaatgtaa gaactgcttt
     6361 aaagaagttt gaaagatatg gatttctaac aaatgaatca acaaacaaaa ataggcttat
     6421 aactattgaa aactgggaat tatatcaatc taatgaagaa aatcaacaga ctaatcaaca
     6481 tgcaattaac aagcaactaa caactaacaa gaatgtaaat aatgaaaaaa gtaaaatata
     6541 cagtgaaatt atagaaaaat tcaatattac ttgtacagaa ctatcaaaag taaagaaact
     6601 tacagaagct agaaaaaaag taattaatgc taggataaaa gaatatgata aagagactgt
     6661 attagaaatt attcatatag ttagtaaaac tagcttttta aatggaagca atgaaaaagg
     6721 ttggaaggca aattttgatt ggataatgag cccaaataat tttattaaga tattagaagg
     6781 caattatcaa gataaatcaa ttaatgtcaa agtagatgca gaggtatata gtccagatga
     6841 ttcacaatta aagtggtagg gagtttatat tatggataat atgagtaatt tagttaagaa
     6901 cacagaagca gaacaatcta tattaggtag tattttacta gattcgagga aaatagaaga
     6961 gattgagata ttaataagtg aagatatgtt ttatcatcaa gaacacaaac atatattcaa
     7021 ttcagtgaaa gatatacata aaagggatga gcctatagat ataataactc ttacagaaga
     7081 cttaaagaaa aaggggctta tagattatgt tggaggtata agttatttga caaaactatc
     7141 aacaatagtt ccaactatag gtaatgtatc tcattatatt gagatagtta ttgaaaaata
     7201 taaaaataga aatataattg ataaatttaa taaattcaaa ttaggtgaaa tagatgataa
     7261 tacacttata tatcaattag aaaaatacat taatgaagta aatcagaaat tggttaagaa
     7321 ggattctagt ataacagcta tatcagagag agcctttgaa tacataaatg atgaaattga
     7381 agaaggtatt aatataggaa taaaattttt agatgaaact attggaggtc tatatagtgg
     7441 tgaattaatt acaatagcgg ccaaaagtgg aagaggaaaa acagcactag ccttacagat
     7501 aatgagaaat gtagtatttc aaggtaaaaa agtacttttt ataagtggtg aaatgagtga
     7561 tatacaaatt ttgtttagaa acatagcttc tttaactgga atatcagttg taaaaatgaa
     7621 gaatagaaat ctaaatgaag aagaaataat taaatacata aatgctttaa gtactttaaa
     7681 tcaggagaat aatctctata ttaatgattc agtgaataca atatcaggaa ttaagaggga
     7741 gataaaaagt attaaaccag atgttgttat aattgattat cttcagattt tggattatga
     7801 aggtaaagaa gttggagaag ctaaatttgc tgatttatca aggcaaataa aaaagattac
     7861 tttagacttt aatattccaa ttatacagtt ggcccaatta aatgatgaat tgaaggatga
     7921 aagaccaaaa ggtgatagag taatgagaag ttcaaaacaa atatatatgg attctaattc
     7981 agttatatat attcatagac ctacagagaa agaggctctt gattattgta agacaatggg
     8041 aatagaggat ataaaagaat taagatgtag agaaaaaggt tttggagcta atttaagtga
     8101 gattatagtt gctaaaaata gagatgggga atcaggtttt agaccttatt ggtatatagg
     8161 aagtttgttt tcttttaggg aatgtaagaa gacaaaagag atatgaaaag aaacataatt
     8221 tattagatga tatgtaaact attgtctaag gagtgttaga agaaaagtat ataaatctta
     8281 attatatgca atcaagattt aaaatatata gtatttagat taaaaaattt attagaaaaa
     8341 ggtagttgcc atataaatat aacaactacc tttataaatt aggtacttaa tgtacactaa
     8401 cctacacaag ttaagtatat attaagtacc agatgaaagt caaggaggta ctaacatgta
     8461 cgatgaaatt atagaaatat attttgatta ttggataaat aaacatatgt atagagatat
     8521 tttagaaaaa gaggagtatt atattgaaat ttggaaaaaa attagggtat ttaatgagtt
     8581 gttaaagaag aatttattag aagagaatga aatacataca ttaatggaat taaatgattt
     8641 atttaattcc gttatagaat ttgaaagaga acttagttat aagtttggat ttcaagcagg
     8701 agcaaaattt acagttgagc tattaaaata attaatttat gatagttaag tgaaagtcca
     8761 aatttattaa taaattatat tataatattt tgaattaact aaatttatac ttatattgtt
     8821 taaaataagt atattttgta aatagggggt aaaaggccct ctttaatttg taatatatta
     8881 taattagact tatattatat taaattagga aatgaggctt attgaaatat tgaatttaac
     8941 aaaataagat ttgtatgttg tgattatatt agaaacttta ttatatttat ggaagaaaat
     9001 atatactatg ataattttac tcacttatat tagtaaataa aatatatgat tacaattcta
     9061 aaatagatac ttaatagggt taagtaataa ttatatgttt atttttagtc ttataaaatt
     9121 aggtataaac acagtattca taaaaaatat ataaatatat atagttagtt attttattta
     9181 tacaacttaa atcaatatag tataataaat agtataaaga tttaggggga gatgttgaca
     9241 aatgactaaa aaagatatga gtgaaagaga catatgcact aaatatataa cacctgctct
     9301 agttgaagca ggatgggata taaaaagaca aataagagaa gaagttacat ttacagatgg
     9361 aagagttata gtaaggggaa aagtaacaac aagaggaaag aaaaaaagag cagactatat
     9421 tttatatcat aaatccaatt tacctatagc agtagtagaa gcaaaagaca ataaacactc
     9481 tataggagat ggaatgcaac aggctataaa ctatgcagat atattagatt tacaattcgc
     9541 ctactcatct aatggagatg gatttataga gcatgatatg aaaaatggaa cagaaaaaga
     9601 aatatcatta gaaaaatttc catcaccaga agaattatgg aatagatata aaggtataaa
     9661 gggaataact ccagcgcaag aagaaattat aacagagccg tactactttg cattaggaga
     9721 taaaatacct agatattatc aaattatagc agtaaataga actatagagg cagtagcaaa
     9781 aggtcaggat agaatacttc tcgtaatggc tacaggtaca gggaaaactt acactgcatt
     9841 tcagataatg tataggctta gatcatctgg aactaagaaa aagattttat tcgtagcaga
     9901 tagaaatata ttggtagacc aagcaataca aaatgatttt aagccattcc aaaaggtaat
     9961 gattaaagtt gaagatagaa aaatggatag ttcatatgaa gtatttttag cattatatca
    10021 acaacttagt ggagcagaag atttagaagt atttaaacaa tttagtcctg atttctttga
    10081 tttaataatt attgatgaat gtcatagggg ctcagcaaag gatacatctg cttggaggaa
    10141 aatactagat tactttagtt cagcaacgca agtaggattg acagctacac caaaagaaac
    10201 taaggaaata tccaactcag catactttgg agaacccatt tacacatata gcttaaagca
    10261 aggaatagaa gatggattct tagctccata taaagttata agaataggtc tagataaaga
    10321 cttagaagga tatagaccaa taaaaggtaa gcttgatgac tacggaaatg agttagaaga
    10381 tagggaatac aatatcaaag actttgataa aaatctaata attgatgata gaactaaagt
    10441 tgtagcaaag aaagtaactg aatttttaaa gaaaacagat aggttttcta agacaatagt
    10501 tttctgtata gatatagaac atgctgaaag aatgagaaga gctttaataa atgagaactc
    10561 tgatttagta gctgaaaatc ataaatatgt gatgagaatt acaggagata ataaagaagg
    10621 aaaagctcag ttagataatt ttatagatga agatagtaag tatcctacaa tagttacaac
    10681 aagcaaattg ctgactacag gggtagattg caaaacttgc aagttaatag tgttggaaaa
    10741 taacatagct agtatgactg aatttaagca aatcataggt cgtggggcta gattaaagcc
    10801 tgattatggt aaagaatatt tcactattat tgattttaga aatgtatcta gattatttgc
    10861 agacccagat tttaatggag agccagttgt tatatatgaa ccagaagaag gtgaagatat
    10921 tacaccacca gaaccagata atacttatga agatgatgaa attaaagaag aacatactaa
    10981 atatagagta tcagatgtaa aggtaaaggt tataagtgaa agagttcaat attacgataa
    11041 agatggaaaa ttgataacag aatcacttaa agattattca aagaaaaata taaaagaaaa
    11101 atttgaagac ttagatgctt tccttagaaa atggaatagt gaagataaaa aacaagcaat
    11161 tatagatgaa ctagtagagc atggagcact actagatgct ttaagagaag aaataggaaa
    11221 tcctgatata gatgattttg atttgatatg tcatgtagca tatgataaaa agcctcttac
    11281 acgctctgaa agagctaata acgttaaaaa aaggggatat ctatataaat actcagacac
    11341 agcacaaaaa gtcttagaaa gtcttttaga aaagtattct tcagataaaa gtatagattt
    11401 aaaagatact aaagttttag agttgaagcc atttgatgaa tttggaaatc ctctaaaaat
    11461 agttaaggct ttcggtggga agaaaaaata tatagaagca ataaaagaat tggaaaaaga
    11521 aatatatgtg taagttaaat tgtagaagag tttcttaagt aggaactctt ttatcatcct
    11581 aaaatataaa tttaatggta aaatataatt agacaaaata ggaggaattt ttatatgagt
    11641 ataaataatt tgataaaaag attacaaaac ataatgcgtc aagacgcagg tgtagatgga
    11701 gatgctcaaa gaatagcaca aatagtatgg atactattct taaaagtata tgatgctaaa
    11761 gaagaactat gggaattcca tgatgatgat tatgaaagta taatacctga aaaccttaga
    11821 tggagagaat gggcagttga cgaaaaagat ggacaagcaa tgacaggaga tgctttgtta
    11881 tcttttgtta atgatgaatt attcccaact ctaaaaaatc ttgaaataga tgaaactact
    11941 gaaaaaagaa gtttaatagt taaagaagta tttgaagatg cattcaatta tatgaaagat
    12001 ggaactcttt taagacaggt aataaatgtt atagatgaaa tagacttcac agaagcagaa
    12061 gaaaggcatt cgtttaatga tatatatgaa acaatactta aagaccttca aagtgctggt
    12121 aaatcagggg aattttattc gccacgtcca accacttcat ttatagcaca aatgttaaat
    12181 cctaaaatag gagataaatg tgcagacttt gcttgtggca ctggaggatt cttaatatca
    12241 atattagagc ttttaataaa acaaataaat actgtagaag ataaagaaat agtaaataaa
    12301 agtttatatg gagtggaaaa aaagaattta ccccatttac tttgtataac aaacttacta
    12361 cttcatgata tagatagtcc taatataata catggaaact cattagaaaa gagtgttaga
    12421 gattacaaag aggaagatag atttgatgtg attgcaatga atcctcctta cggtggagtt
    12481 gaacaaaaga atatacaatc taatttccct gtagaattac aaacatctga aacagcagat
    12541 ttattcgtta ctacaatatt atatagatta aagcaaaatg gtagatgtgg aataatactt
    12601 ccagataatt tcttatttgg aacagaaaat tcacaaaaag cattaaaaga gaagttgatg
    12661 aatgagtgta atttacacac tatagtaaaa cttccagcag gagtttttgc tccatataca
    12721 agtataacaa ctaatatgtt attctttgat aaaacaggag ctacagaaaa gatacattac
    12781 tatgatatac cacttccaaa aggatataag agtttctcaa aaactaagcc ttttagagat
    12841 attcatttag atgaggttag agcttggtgg aatgatagag ataatggtaa tgaaaatgct
    12901 tatgttgtaa ctaaagatga agttatagct aatggatata acttagactt taaaaaccct
    12961 aataaattgg tagaagaaca tgaatttaca ctcgaagagt tgttatctta tatggatgaa
    13021 aagtctaaaa atatatctag tttattagaa aaaatagcta tggaacttga aggagttgaa
    13081 gaataatgga tacaaaatca ttaaaagata aaattcttca attagctata caaggtaagt
    13141 tagttcctca agatgaaaat gacgaacctg catctgtttt attgcaaaga ataaaagagg
    13201 agaaagagca gttaataaaa gataaggtta taaaaaagga aaagccatta tctgatataa
    13261 tagatactga aaaatcactt gatttaccat ctacatggga gtggtgcagg ttaaatgata
    13321 tatgtaaatt gattacggat ggaactcata gtacaccaaa atatactgaa aaaggcatac
    13381 catttatttc tgtaaaagat attacgaagg ggtttataga tttcttaaat acaaaattta
    13441 tatctagaga agaacatgaa gtattaataa aaagatgtaa tccagagtta ggagatgtat
    13501 tacttacaaa agtaggaact acagggattg ctaaagtggt agatacatca aaagaattta
    13561 gtatattcgt tagtgtagca ttattaaaac tttttaatag tgaaatagat tctaagtatg
    13621 tcgaactatt aataaattct ccttttgtaa aaaaacaatc agaggaaaat actcaaggag
    13681 taggaaataa aaatttagtt attagatgca taaagaattt tataatacca ttaccaccat
    13741 tggcagagca aaaacgtata gtagcaaaag tagatttatt atttgaatta atagatgaat
    13801 ttgataataa taagcaagat tttttacagt atatatctga ttcaagaaat aaggtattac
    13861 agttagctat tcaaggtaaa ttagtttctc aagatgaaaa tgctgaacct gcatcgatat
    13921 tgttagaaaa aataaaagaa gaaaaacaac agttaataat agataaagtt ataagaaaag
    13981 aaaagtcatt tccagaaata acagatgaag aaaaagcctt tgagctacct aatggatggg
    14041 agtggtgtag attaggagat ataggtgtat acaaaaaagg tccttttgga agtacaatta
    14101 caaaaagtat ttttgttcct aagtctgaag atacagtaaa agtatatgag caaaaaaatg
    14161 caatacaaaa agattggaca ttaggagaat accatgttac taaagaatat tttgaatcta
    14221 agttaaaagg atttgaagtg tttgaaggcg atataatcgt aagttgtgct ggtacgattg
    14281 gagaaacata tataatgcca agcggaatag aaaaaggtgt tataaaccaa gctcttatga
    14341 aaatgaagct gtataatggt atcaatatag attatttctt aatgtatttt gattttatat
    14401 taaaagaaac atctaagaaa tcaagtaaag gttcagctat taaaaatata ccaccttttg
    14461 atatattcaa aaaaatgtta ttacctttac ctccattgga agaacaaaaa cgtatagtag
    14521 ataaagttgc tactattatg aattacttcg ataagctaga aaaagaaatc ggttaaaata
    14581 aaaagtggta gttattagaa ttattaaaat agctaccact ttttattagt ttagaactaa
    14641 aaaaagtcat aaataatagg atagggggat tagattattg gagttaaagt tagttttaca
    14701 aaatattata gattgggttg taaatcttga taatacatac ataattcaaa tactaactaa
    14761 tataattaca tctataggag ttgtatttgg attcatattt tcaatagtaa cacttcgaca
    14821 atcaaaacaa gcacaaatag agtaacaaaa agagattgaa aataatagct ttgaagatcg
    14881 aagaggtata tttgtagttt tgggaagaat ttatgcttag taaatctgat atatggatag
    14941 ctccaggtta aacatataaa tatttatgta acttagatga agttatgcat ggcaataaga
    15001 ataaccttga agttttttct gtgaattata aatatgaaac atttagatgt atatgataaa
    15061 aatggtatat atgcagatat agaagtggat atcaaaggca aaaatgataa gattactaga
    15121 aaaaaataaa agtaaaaact aatgataaac tagaagataa aacagataga agtatatatt
    15181 ctgaatatgt tatatcaagc ctaaattatg atttagaaaa taaagaagta gtttttgaaa
    15241 atggtactat tttaaaagta gtagagtcaa ttgggaatac aaatgatgat taggttaaat
    15301 accaacaaat aaaagctcat ttagataagg agttattatt agttaaaaaa tatataaaag
    15361 ttttaagttt atttttttta gatgaagtta agagctatca gatatataat gatgataaaa
    15421 ctatatcaaa aggtaaatat cgaataatgt ttgaacaggc atataaagag ttaatatata
    15481 aacccaagta ttaaacatta ttaaaaagta agataaaaaa tatagaagag ccagaaagag
    15541 taaaaggttt atattttgca gaatattcaa aaaacatagg caaatttaag gactcaaaag
    15601 aaaggaagtc agggtttagt gcagatgatg tgagagcttt tgacttaata atgaaaagaa
    15661 aagaactatt attgagtttt gattcttcag tcagatttat attttctcat tcagccctta
    15721 aagaaggttg ggacaatcca aatatatttc aaatatgtac attagtaaat aataaagata
    15781 cttttacgaa aagaaaaaag ataggtagag gacttcgatt ggcagtaaat caagatggtg
    15841 aaaggataac tcatcagaag gatgaaactg taaatgtatt aactgtaata gcaaatgaat
    15901 catatgatga atttgcatct gctcttcaat tagaaatcca agaagagtgt ggaattaaat
    15961 ttggccattt agaagaaaat tcatttcaaa atatagttat atgtagagag gatgaagata
    16021 ttcagttagg atatgaagct tctaagtata tatttgattt tatgattaat aaaggatatt
    16081 tgtcatcaaa aggcaataaa aaaggaaaga ttaatgaaaa actaaaaagg tgtatagttg
    16141 atgaaaaagt tgaaatacct cttcaatatg aaggtattaa ggatgagatt ataaatgtta
    16201 ttaagagggc tatcagaagg ttacctatag gaaataataa agacagagtt gtgataaaac
    16261 caagaaaaga aattttacta agtcaagagt ttacagattt atgggataga ataaagcaaa
    16321 agactattta tcgtgttgaa tctaatgatg agaaatttat agatatttgc cttaaaaaga
    16381 tggaggattt aaagcctaga aggagtaaga ttaacataga tagggtagat atagaaatta
    16441 aatgtaaagg tgttgagata gaatacaagg atacaataaa acaaaatttg aagcaaaaaa
    16501 cttataagtt accagatttg ataagagata tacaagatgc tacaatgata actagatcta
    16561 ctataataca tattttactt aaagcaaata agtgggattt atttaaatta aatccaaatc
    16621 aatttataga aaaaactata aaaatattta attctgctaa gagagagctt attgtagatg
    16681 aaattaagta tgaaaaagta gatgattatt atcataaaag tcaatttgaa attgaaaaag
    16741 atatattaat agggtattta caaaaaaatg ctatagctac aagtgaggaa aatcaaaaat
    16801 ctttgtataa ttatattcta tatgattcat atatagagaa aaaatttgct gagaaattag
    16861 aaaaagatga agaagttaaa gtatatgtta aacttccaag ttggtttgaa atagatactc
    16921 ctattggtgg gtataatcca gattgggcta ttctcatgga agagaatgat ataaagaagt
    16981 tgtattttgt agttgaaaca aagggatcat tagatgatga tgatttaaga aaaagagaaa
    17041 gagataaaat caattgtgct aaagaacatt ttaaggcttt agaatcaggg ataagatatg
    17101 tagttgagac cgattttgat gatataaagg agtgaaagta gataagaaaa agtcttttat
    17161 ttttaaaagt ttcaagtggt gtttaaatat gtatgaaagt aatattattt ttataaactt
    17221 taaaaattat accccaacga taccccaact ataaaaacaa acaataaaaa ataaccaaaa
    17281 aaatcagtct aacatcataa ctaaatagct atatacctat acttataaaa accaacaaaa
    17341 caatcaaata accacttatc gactcccctc gtctccacca ttgaaatcca cgaaaaacat
    17401 attgatagtt ttgtcaatat gttttttttg tgccatgaaa tgatataatt ataatataaa
    17461 ctaatttaaa atttaattaa aaggagatag tataagtgag tatagataat aattttaatc
    17521 atattgcttt tttatggaat atagcagaaa gtttaagggg tacatacaaa gaagaagact
    17581 acagaaaagt aatgttacca ctaatagtaa taagaagatt tgattgtcta ttagatgatt
    17641 atgatagaga aatagtgaaa tcagtataca aagaatatga tttcttacca gaagaagaaa
    17701 aagacgaact tgtaatagtg gatctaaaag aaaaccataa tatagactta cagttctaca
    17761 atgtgagtga ttttacatgg aaaaaactgt tagatgatag tgaaaatata aaatcgaact
    17821 ttgaagaata cctaaatgga ttctcaaaca gtgtaaaaga aataataggg aaatttaaat
    17881 tcaaagatga aatagctcaa ttagataaaa aagacaagct atatgcagtc cttagcaaaa
    17941 tgtatgaagt agacctacat ataaactctg tatcaaacaa cgaaatggga tacatatacg
    18001 aagaaatgct aagaagattt acagaaaact cagcagcagg agaacaatat actccaagag
    18061 aagttataag actttgtatg gaaatgttat ttatgggcaa agaaaacttc cttacagaag
    18121 aaggaaaagt aatatctata gcagattttt gctgtggtac tggtgggatg ctttcaatag
    18181 ctgaagacta tgtggaaaaa gtaaatccaa gtgccatagt aaatgtatat ggacaagaat
    18241 tactagatga atcatttgca atatgtcagg cagatatgat aatgaaagga caaaatccag
    18301 ataatataag actaggaaat actcttacgc aagatagatt tagtggagaa aagataagat
    18361 ttttaatatc aaatccacca tttggtgtca catggaaaga tgaagagaag aaagtaaaag
    18421 aagaagctga cttaggattt gatggaagat ttggggcagg aacaccaaga gtaagtgatg
    18481 ggtcgttact attcttacaa aatatgataa gcaaaatgta tgatgatgaa gaaggtagta
    18541 gaatagctat aatattcaat ggatcaccat tatttacagg agatgcagga agtggtgaat
    18601 ctaacattag aaaatggata atagaaaagg atttactaga gggtataata gcactaccta
    18661 ctgatatgtt ctataacaca ggaatagcta catatatatg ggtacttact aataaaaaag
    18721 aggataaaag aaaaggtaag atacaacttg taaatgctag tgaatattat caattaatga
    18781 gaaaaagttt aggaaataaa agaaaagaaa taagtcttga acaaatagaa gaaataaaag
    18841 aaatatatga aagatttgaa gaaagtgaaa atagtaaaat atttgacaat gaaggctttg
    18901 gatatagaaa agtaacaata gaaagacctt taaaactgag ctttagagta aatgaagaag
    18961 ctatagaaaa tgttaaaaat actactcaat ttataaatct ttcagtttct aagaaaaaag
    19021 atgaagaagt taaagttaag gaagaagcag aaggaagagt aaaacaagat aagttattaa
    19081 aacttttaga aagttttgat agtgaatttg agtatatgaa gagggataag tttattaaag
    19141 atttaaaatc taagtctaag ttatatgatg tagctttatc agcaggacta attaaagcta
    19201 tagttaatgc tataggagta agaaatgaag acgcagtagt ttgcaaagat gctaaaggga
    19261 atatagagag tgatagtagt ttaaaagata ctgaaagtat agcacttaaa gaagatgtgt
    19321 atgagtattt tgaaaaagag gtaaaacctc atgttgaaga tgcttatata gatgaaagta
    19381 gtatagataa tataggatat gagatacctt ttactagata tttttataag tatgaaaagt
    19441 taaaaagctt tgatgatatt atgaaggaag ttgaaagttt agaaagtgag atagcactgg
    19501 agataaggaa ggtgctaggg taatgagata tagatataga gatgatgagg aaatgaaaga
    19561 tagtggagtt gagtggatag gtaagattcc taaggattgg gaagtaaaaa gaataaaaca
    19621 tttatttgaa ttaaagaaag ataaatctga tgaagaaaat ccaacggtat tatcattaac
    19681 tcaaaaagga ttaaaaataa gagatgtaag taataatgag ggacaattag catcaacata
    19741 tgtaggatac actaagattg aaaaaaatga ttttatactt aatccaatgg atttaatatc
    19801 aggatatact gataaagcag aaattgaagg tgtaattagt ccggcatata ctacctttag
    19861 aagtaaaaat aaagtaaata ttaatcacga ttattataaa agatattttc aaatgcatta
    19921 tcatcataat ttcttattcc cgtggggaga gggggtatca ttcgaacata gatggacatt
    19981 aaaaaatgaa gtatttttaa atcttccagt aataacaaat aggttagaag aacaagaaaa
    20041 aatagctaat ttccttgatg aaaagacttc acagtttgaa tttattatat ctaagaaaga
    20101 agaattaata aaaaagttag aagaagctaa aaagagcctt ataagtgagg ttgttactgg
    20161 taaggtgaag gttgttaaga ctgatgatgg atataagctt gtgaagagaa gtagtgaaga
    20221 aatgaaggat agtggaattg aatggttagg tgaaatacct aaggattggg aagtgaagaa
    20281 ctttaagtat atgtttactt taaataaagg tttatcaata acaaaggcag acttaaaaga
    20341 aagtggaata ccgtgtgtaa attatggaga gatacactca aaatataggt ttgagcttaa
    20401 gcctagtaaa cataaattaa agtacgtaga tgaatcatat ttaaaatcga attctatttc
    20461 attattaaag tacggagatt ttgttttttg tgatacatca gaagatatag aagggtgtgg
    20521 taattttaca tatttaaatg aaaataataa ggtgtttgct ggataccata ctataatagc
    20581 tagaacttta gaacaagtaa actatagata tatgtcgtat ctatttgatt caaatgattg
    20641 gagaatacaa atacgcacaa aggtatcagg ggttaaagtt tttagtataa ctcaatcaat
    20701 attaaagggt acaaaagtaa tactaccaga tttattagaa caaaggaata tagctcagta
    20761 tttagatagt aaatgtaaag ggatagattc tattatagat aaaactaaat tacaaataga
    20821 taaactaaaa gaagctaaac aaagtttaat aagtgaagca gtgacaggaa agatagaaat
    20881 actagactaa ctcttagtat atttgaacag aggtgaaaaa tatgaaatta agtagaaaaa
    20941 atataacaat gcaagtttta tcaaaattta tagaaaataa cttagaaaaa atagaaaacg
    21001 tagaaacaaa agcaaatcaa atagttttta gaactataga tggtgacaaa aaaataaaga
    21061 taaaaacaag taaaaattat agcgaaggag aagatcctaa tacatattta tggacaagtt
    21121 tttctagtga agaattagaa gaagattatg attattatac tataatatgc aatgaagata
    21181 tagaaaaagc tgtggtattt acaaaagaag aattaaaaca acactatgta ctagaaacta
    21241 agaaaaagaa aaatagagaa attgattttg aattatatcc tcattttata ggaagaagat
    21301 gtatagatgc tagagttcat ttatataaag aaccaataga tataactaag tatgtaaata
    21361 actatatatt ttagtaatat atataatcaa taaaattata ttttacattg ctttatgtag
    21421 gagattatat tgatatgaaa acattaaata taagatacaa agatggattt aaaatagaag
    21481 aagatacgag actttatcct ataaatagtg atataaatga taaaattgga gttcttgtag
    21541 aacatagaaa actaaatgct actaataggt atttaagata tggtatacaa aaaatttcgg
    21601 ggaagtgtta tttttttgat gtaagaaata gtgtaatatc aaaaacaaag gagagtgcat
    21661 ataatacttt tatatgtcct tattgcagag aaagaatgtt tatagtatca gcatttgaaa
    21721 gacaatgaag catagtacca attcacttga aacattataa aaagacaaat aaataatgta
    21781 tatttagaac agattctaaa agtatgaaac taagacagaa ttattatgaa ttagaagaat
    21841 ttatacatag agagatacaa gattatgtat gtaaaagtgc acaagaaggc tttaaattaa
    21901 gtatacagag ttcatataaa ttatataaaa atctacatac caatactata agagcagata
    21961 tacaaaaaga aagagttaat attgtaaatg ctattccaat ttataataca agtcaaaaaa
    22021 ataataaaaa atatacaccg gatataatac tttacactga taacaataga gaaatatatt
    22081 gtgagatatc agtttataaa tctgtaaata cagcagatta ttttgatgaa tggaaagttt
    22141 taggtaaaac agtaatagaa ataaggaaaa ctgaaattat ggatatgcat ttagatggat
    22201 atagactttc taaggattta ataatatctt atttatatga ccctatttta gataaagcta
    22261 gaaagcaaaa aataagtgaa tctcaaaaga ttatagataa gtcaaataat ataatatcta
    22321 aacataaaaa tttaaataaa gaaaataatt caaaggaaaa aatacgtgaa aaagaatata
    22381 aagaatttga tgataaagtt aattatgata taaaaaaaaa cttaaataat ttaaatgaaa
    22441 ataatatttt gatcaaagaa tatgtagata aaaggacaga taagcagaaa aggagcgata
    22501 agcgtaatgg acgtgaacct aaaaaagaat tagtatattt tgatgttaaa gcaaataaag
    22561 aagcaagaat tatatatgca gtaattatga aaaatagcaa aagagcttat cgaagtatac
    22621 ctgcaataat aggaaaatat ttaagagatg atggctataa agttggtgtg gctggtaaaa
    22681 aacgtaagta gttaatgatt aatataagct ttataatata tagattaaca atatagaaat
    22741 gggggaatag caatgttacc aaaagagaaa catttagaag agtctattga aaatcattta
    22801 gtttcaattg gatacgaaca aggtcattca caagaatttg atcttgaaaa ttgcttattc
    22861 gtagaagatt tatttagatt tttagaaatt actcaaaaag aattactaga tgagttcaaa
    22921 tacaacaggg gaagtaatta caaaaaagcc tttatagatt taattaactc aaacatcaaa
    22981 agaagggggc ttataagtgt acttagaaat ggtgtagaag atataatgat gaacggaaaa
    23041 ttccaattat tctacaacaa accaaatcta actactaaca aaacagctta cgaaaattat
    23101 aagcaaaata tattcaaaat aacaagacaa ttaaaatata gttcaaagca caacaatact
    23161 ttagatatag tattatcttt gaacggattt cctgttatag taatggaact taaaaaccaa
    23221 ttcactaatc aaaatgtgta taatgctata aaacaattca aacaggatag aaatccaaaa
    23281 gaaactttat ttggatttaa tcaaagagta tttgtatatt ttgcagtaga tactgacgaa
    23341 gtatatatga caacagagtt aaaaggagat aaaacattct tcttaccttt taataaaggt
    23401 aacaatatgg gtaagggaaa tcctgtagta gaaggaaaag aaaaaacttc ttatctttgg
    23461 gaagaaatac ttactaaaga tagtttactt gatattataa agagatttta ctttatccaa
    23521 gaagatgata agaaaagtaa aagagctata tttcctagat ttcatcagct agatgcagta
    23581 agaaagatag tagcggattt agaagtaaat aaagcaggta aaaattatct tatccagcat
    23641 agtgcaggta gtggaaagac taatactata gcatggactg ctcatagatt atcaagcctt
    23701 catgatgaag ataacaatgc tatatttgat tctgtaatag tagttacaga tagaaaggta
    23761 cttgataagc aacttcaaga tgctatatac caattagaac acaaaaacgg attagttgtt
    23821 aagatagatg atgataaaaa ttcatcagat ttagctgatg ctattgtaaa cagagcaaag
    23881 attattatta caactataca aaagttccaa tatgcattac ctaagataga acaacttgaa
    23941 aaaagacgtt atgcagtaat aatagatgaa gctcattctt ctacatctgg tgagaatatg
    24001 aatgcattaa aagaaacttt agcaggaaaa acattagaag aagctaagat aattgatgct
    24061 gaaaatgaaa agaatgaaaa atctagtata gacaagatga atgaccttat agaaaagaga
    24121 actaatttag atcatataag tttctttgca tttactgcta ctcctaagaa taagactatg
    24181 caagtatttg gtagaatagg agaagatgga ctacctcatg agtttcattt atattctatg
    24241 aagcaagcta tagaagaagg attcatatta gacgtattaa agaactttat gccagttagt
    24301 gtatattata aggtaggtaa aaaaatagag gataatcccg aatttgataa aggagaagct
    24361 aaaagagcta taaacaaatt tattagttta aatgaacaca acatacgtca gaaagttgaa
    24421 actatagtag acgattttgt ggataatagg tctatgtggt tagaaggcag agctaaggga
    24481 atgatagtta cagcaagtag attacatgct gttaagtata aattagcaat agatcaatat
    24541 ataaaagaaa aagggtacaa tatgaaatcc ttagttgctt tttcagatac tgtaaaagat
    24601 gaggatattg aatatacaga agttggtatg aataaggaag tagcaccaga tattaatgat
    24661 tcaaatttac caagtatttt tgaaaaaagt gactttagat tacttatagt tgcagaaaag
    24721 tatcagactg gttttgacca accaaagtta tgtgctatgt atgttgataa gaagttagat
    24781 ggtgtaaaaa ctgttcagac tttatcaaga cttaatagaa catatcctaa taagcataca
    24841 tttatcttgg atttccaaaa tagtgtagag gatattcaag aagcatataa accatacttt
    24901 gaaatgacaa acatagataa agttacagag cctaatgtag taaatgatct ttggtatcag
    24961 ttacatgaat atggtatata tactgatgag gaagtaaatg actttgcagt attattctat
    25021 aaggataaaa gaacaaatac acaagatgct aagatgaata gtttaattga taaggcagtt
    25081 gaaagatatt gttatttaga tgaagaagat gaaaagtcag cagatgagtt taagaaaaaa
    25141 tgtcaaaagt atattacttt ttataatttc ttaatccaaa tttaccctat aaagaactta
    25201 aatcttttaa ggttacaggt ttacttagta gcacttttaa ggaagctacc taaaaagggt
    25261 aaagaaagaa tagatataga tgatatttta agtttagatt attataagtt acaaaagtta
    25321 ggtgaagatg gtaaaaaagg tagtgatata tcattatata atggtgaagg tgaattagtt
    25381 ggtatatctg aaactgctac ttctcgtgta agtgaagctg atgaagaata tttagaagat
    25441 ataatccaaa aaataaatga tgtctttgga gtaggactta cagaggaaga taggattata
    25501 atagatcaat atgaagagat gtttaaaaat gataagagta ttatggatat agctaaagct
    25561 aacagttatg aagatttggt tagtactttt ggaaagagtt attttaagag aggtatagtt
    25621 aagactaaga atatgaatga tagattggtt aaagaaatat taactaataa taatcttcaa
    25681 aattatatga ttcattattt ggctgaaaaa atatatgcag aagcaaatag ataaataaaa
    25741 aggagtacaa tatgacagat aaaataataa aacctaaaaa tttattcata tatgaattaa
    25801 agtgtgactt aattgaagat gatgaaagat ttgtaattaa gggtaaatta gataaggaag
    25861 aaataaataa tttaatattt tatttacaag ttgagtttag aaatatatta gataattcca
    25921 tattaatacc atacgatata agtaatatat taactagact atatgggttt gaggaagtac
    25981 aaaatattga agatatatca atagatcaaa cgatagaatt aacagataat atagatgaaa
    26041 atatatacaa aatagatcaa atattagaaa atagatcaaa cctatatgtg gatgggttat
    26101 atgatatgct agaaggtata aagttagaga gtgtacaaga taatccgact gtatttgaag
    26161 aagagtatgt aaaacttcaa aataaataag gaatctagta aaatgtaata attataatta
    26221 tatattataa ttttgaaata tacattaaat agatatcata ctaaagagga acatacaaaa
    26281 aataacacat tgagatgttg gtagagatac taacatctct ttttttagtt caaaaaatta
    26341 taaggaggaa attaaaatga ttaacttatt taagaaagaa gatttaaact tattattaga
    26401 atatccaaag gaagtagttg aaaatgtgga taacgttata aatattcttg atgaatcata
    26461 cggagataac agaaaaataa cagataatgg tggatatgtg tgtataattg aggatattaa
    26521 agaaatagaa tatttaaaat cacatatatt aaatggatta attgaagagt ttagtgatgt
    26581 aatatatgaa agtgaggttg atatctacaa ttcaactcta tatttactat ctagtgacta
    26641 tagcattact ataatatcta aaaatgaaga aactgaacac ttacttaaat aagcatatac
    26701 attgataaag tgtatatgct tattttaatt ttgagaaaca aaggaggaaa taatcatgga
    26761 taagaaaaaa atacctgcaa aaagagttga tatagtatca cttaaactag taaaagaaag
    26821 tagtgttcta tatgaaacta gaaaaataag caatccttat gatgcttata gattagtaaa
    26881 gaacttttta gtagatagtt atagagaaaa gtttgtagta gtatgtttag atacaaaaaa
    26941 tcaaccagtt agtatagaaa ttgtaagcat aggaactgta aattcagcga tggtacatcc
    27001 aagagaagta tttaaagtag tagtattaag taatgcatct aaaataatat gctttcataa
    27061 tcatccatca ggtaatacta actttagtaa agaagatgaa gttataacta aaaggctaca
    27121 gaagtgtggt gaaatattag gtattgaatt agtagatcat attgttgttg gagacgatga
    27181 taagtatttt agctttaaag agaattttaa gatatgagag tcttagctta aagaaattag
    27241 gctaagactt tttctatgtt ctaaactaat tgaaataaat tagttttaag ttaagcccga
    27301 aaagcccttg aaaaaataat atacatataa ataattaaac taaataggag ttgtaaaatg
    27361 tttaaaaaag aaaatagata tatgacgaga gaaatagctg aaaatctacc aattgaaata
    27421 actatattac tatgggattt gatagacaac ttagatatag aaaaagatta tctacaaata
    27481 tttgaaataa atcctatagg attaggagta gttgagatag ttcatagaca agaagtacct
    27541 gaatatgaag ctagtatata catacagaat gacttaatta aatacaaatt aaaaatatac
    27601 gctatagata gtattaaata cagtactatg atgttttcaa atgaatatta actaataatt
    27661 aaaggagaac gagtaatatg ataaacaata aatctgaaat aattaataag ctatttttca
    27721 atgaattaaa agaattaata gataaatgca acaacataga agataaaact gtatatatga
    27781 tagaaaagat attcataagt atagaagatg aagaaataaa gaattaccta ataagaaata
    27841 attgtaagtt acaagagtta gtaaatagat acaaaaaact tgaactttta aacatagatg
    27901 aagctatatt ctttgcttgg tacaacttaa atataaatac aatatctata gataaagcaa
    27961 gtcaatatta ctatgagtta acgacaagta actatataga agtagaaagt catttagtat
    28021 atacaaatga gatagattta agagaatatg ctaaagatga attagatact atgttagata
    28081 tggaatatca catagataga ttattagata aagatatgat aatagatatg tggttaaata
    28141 atacatcaaa agaagatgtg atagaagaaa tattaatgag tgatgatatt gaagatatat
    28201 tggatatatc tccagagtat gcattcacaa caactagtgg aatagagtat agatattcag
    28261 aaaaagaaga ataaaataaa tatatgtgtt gaaaaaatac gggctttaag ggcttatacc
    28321 ttaaagtatg tataaaaaat acaatagatt ttacaataga aaatcagaat gaaacttttt
    28381 ctaatactaa ttattattaa tgagtatcag aaaaggaggt ggagtaatga tcaagaataa
    28441 tagcgactat caaagggata tatgcagata tggtagatat tctaggtgaa gaaatagtca
    28501 ttaaattata taagtattat cgtggacaac aaataacatt tcctatgaag ttatactcta
    28561 atgaatatgt agaaagatat atagaaaaga attatagaac aaaaacatta aaagatatgt
    28621 gtagagagtt aggatatacg gaaggttgga taaagcaatt gataaataaa tacaaattaa
    28681 aataaatacc ctagttattg ttaaattatt caataaaaaa tatgatttta ttacaaaaat
    28741 ttataatttc gacaagatga atgttgtatt atatcaacga aagatattaa atttattcat
    28801 atcaaatata aattatcaaa ctttataact aagttatcta ataagagaca ttagtacaaa
    28861 gttcattagt aagtgaacat aaagaattaa ggcaatggag agggagattg aaaatgacaa
    28921 agtttaattt tataggaaat gaaatttata taacagaaga aagaaatagg tataatagca
    28981 taagaataga atatgaaaat atagcgaata aagcaagaaa agaatttatt aaagtatata
    29041 ggtcatgtaa tgaaaatcta gatgatgtaa ttaataatgc ttatgctcaa ggggcatcaa
    29101 ttattttaaa atcaattaag tgtacactag atcgacttat agaaaataaa ttttataata
    29161 taagcgaaga gttatttatt gaacaatact gccaaagagt tgtagaaatt tgggaatctg
    29221 catacggtat aatcaatgac tagtatatga atattgtatt agatgaaagg caaaaggaag
    29281 agtatagaca actaaggaaa aattcaagag ctagatggca aggtggaggt tttgggattc
    29341 aaggggctat aaaaggagct acacaagcag gagcaatgaa tatggttaca ggagttgcac
    29401 attctgcatt taatatgata agtaaaatag gtacgagtat aaaagtaaat aaacaaaaat
    29461 ctaaaatatt taatgatcca tcgacattag atgtattatc tgaagtaatt tatttagcca
    29521 ttttagatat taaatactca tatataaagt ttttagaaaa taatgcagga ttacagtttg
    29581 ggtatataca tgaagaagag gaagaagaag caaatgtgat actttcaaat ataaaaggca
    29641 gaaatttaga tgaagaagaa aaaataaatt taattaaggg acttatagat ttaaatccat
    29701 acatggagtc tctatacaca tacatagtag ataactttgg tgatgaaaat atggaagttt
    29761 ctaagatggc tagttatttt ggttttaata tagagccata caagcttagt ttagtagaga
    29821 ataaattaat taatttagaa actaacacag aagaagaaac aatattagct aagcagctta
    29881 tattaaaaga agtaaataga ttaggtatta atagtaaggt aaatggaatt gaagagttag
    29941 accgaaaatt aaatcaattt gatatagaag cgaggacagt agataacata ttgtttgaaa
    30001 caagagaaaa agctaattta gcaagacaag aaaaattaga tatagaaagt ataataaaaa
    30061 atttagatga aaacaatgaa gaaaatctag ttaatattaa aaaagagatt gaatctagaa
    30121 attttaaaac agaaatagcc gatttatata tagatagaat aaataatcat attaaaaatt
    30181 tatattctga cactataaat gaagcagaac aatatgagga taataaaacg aattttaaaa
    30241 gtacgttaat aggatcagcg tttattgtac ctctaggtat atactttttt ggtaatgttg
    30301 ggattatatt aaagatagtt ataggtatat tcttattatc cgcagtatct gcattatttg
    30361 aatcatataa aaaattaaag gcaagtaagt attcattaaa acaacttaaa aagttaaaaa
    30421 agtcaggtaa aataatataa ttatcatgag gaatcaaatt gaaaggtata tttaataaaa
    30481 cattgacaaa gattataata agttcattaa tatttggaac tgtatgtagt agtatagttt
    30541 atctaggtat gagaaatgaa tttaacaata aattagtttt ttagaaaaag agatactaga
    30601 cttaaaaaaa caaaacgtag aattatctaa taaagaatta gaaaaagaat atgataattc
    30661 agacgttaaa tctgaagatg ttaaaaaaga tagtgagatt actaatgagg taaaaaaaga
    30721 atctgaaaaa gaaatggaac agtatagttt tagtagtgaa ttaatagatg taatggtaaa
    30781 tgctagtaat gacttaaata gagtatatga aaaaataaca agctcaggaa catttagtgg
    30841 attacaaggt acatttgata ctttatatga atatggatta atgttagaag atttactaga
    30901 ggtaatggat ttatctttat taggaggtaa tgaaactaaa gagattattc aaaatatagc
    30961 tatagattta aagaatatat ctgatgaaga taatatagct gataaagcat tagatttaat
    31021 gggtaatata ggggagttta catactatat tgagactaac tatagtaaat aattaaatat
    31081 taataataat agccttgcta cacatgactg tagcaaggta ttatttttgt aaagaaagga
    31141 agatttaatt tggctaaaca aaataaggct caactatttg aaaaagaaac taaatattgt
    31201 aagataatga gaagcgtaac agttgaagat ggagaagaaa gatttgcaat agaaaaaata
    31261 tatgttaagt cattgaaaag gtatgaagtt agaatatgtt tataccgtga ttgtaaggac
    31321 agaatgaata agctaatacc aagaccagtt gatataagcc ctgataaatt atcaacttta
    31381 atattggtag gtataaaggc gggtatttta gatgatgatt ttaagcaaga gctaataaaa
    31441 ggtttatctt aggaggtata gaatgtcgat agaagaattt actagtggag taatgtttgg
    31501 aatttctata tttggtacag tattaaagaa gttattagat aataaaaaat agtacatagg
    31561 aggtgttatt atgattggat ttataatagg aactatgata ggagttggat tatgcattag
    31621 catagaaatt atgatatcaa aaaatacaat agtatattaa cctatattta aactgttaat
    31681 ataatcatat ataatttatt tgagtcctta aagcccagaa aagttttata tgaaggagaa
    31741 ttttataata tgaaatatac actaaaatat ggattaggac aattaaaatt cgatgtaaaa
    31801 ataaggttag aagacatatt aagattgtca tctgcaggag aggataatga tgaagtaagg
    31861 ttagctgaaa gatcaagaga aattaatgat ataattggaa agctatattt aagaccgagt
    31921 gaaactaaga aaaaaatcta atagttatga agaaagtaaa aataaatcta aaagtaaata
    31981 tgatagagat aaaattaagg acatattaga agaagatgag ttgaatgtaa tggaaaagta
    32041 tgtattttca tttgaatcag gaaataataa gctatttaaa gagtattgga aagacagaaa
    32101 gaagacagat ataccattaa taacaacaat attttttaga actatgttaa gattaaagga
    32161 tacatataga catgatttgt ataacttatg ggaagaatgt aatctaacaa cggaagaatt
    32221 taaggaaaat atatataaat cacaaaatga atctatagga tttattaaat ttaaagttga
    32281 aaaaatgata gaagaagaaa aagaaaggtt agggaaaagt attaataaca aatataaaag
    32341 caatagaaaa ataacagaat tgcagaatat tgatattgat aatatagtaa aagaattgat
    32401 tatatctgat aatcctgaaa ataaagaaat ctatcaaaag atgataatta ttacaaaatc
    32461 attttttaag ataattgaat atagaagaaa attatcatta agtaatcaaa cagcaactga
    32521 taatttaatg gaagaggtaa aaaaactata taatacatta ccaaaagaat cgagatatga
    32581 tgcagcatat aagaatctaa gaaagttaaa agaagatatt gaatttaaga taaaagaaat
    32641 agataattat aaggatatat ataaaagaga agttataaaa aattgtaaat tagttagtga
    32701 gtataaaaaa aagaagaaaa actaaagaag tctggttata tagaagaatc agaaaaaatg
    32761 gcaaaaaaat atatagatat agaaaggcaa tttaatgaga gtatgagaaa aaaatggata
    32821 tatatataga tatgtatata agacgtaagg acttagaaat agaagaaatg gatatgaaaa
    32881 aatatgaaga tgataatata acgaattcga tgattaaatt agcagaagag aataactctt
    32941 aattagcata aaaatagtac acagttaagt gtgctatttt ttttatgaaa atgaaaaaaa
    33001 attggataat ggtttggtta ttttttaata aaaaattagc ttatatttaa tttcagaagg
    33061 aggtaaggaa ataaaaatac gggctataag ggctttagga caacttagta ggaggaacaa
    33121 aaatggaact taaaacaata agaattacat ttacagtaag tagtgaaaca agtgaagatg
    33181 atttaagaaa gttatgtaaa gattacatgg gtgatgagta tgttgttaat gatgaaggtg
    33241 actttgaaat atccttttat ttaaatacag tacttggata caatgaggtc ttatacttta
    33301 tggagttgat tcacatggag ctagaaaaaa gtattactct attaggaatt agatacaaag
    33361 gaataggtgg actccaaatg aagcatattc tacaggagga atagagtaag atgattagga
    33421 attgtagtaa gataattaag aactatggtt ttaaaataaa cagcaaaaat catgtatttg
    33481 atagtaatgg aaatgagatt tgtaactttg taccaattgt attaggacaa tacatgatag
    33541 gcggtggaag agatcgaagg acagttattg tattgatggg aatatcagag gacggtaatc
    33601 aactagaaac tattaatata gatgttagcg atatagagca tttgaaatgg gttaagaata
    33661 gctggggatt tcaatataaa gtacattcta aaatgaagaa tcaatttcta tacttaatag
    33721 aagtattagt tataaatgga acaactaaga agttaagtag tcaaattgga tgggttaagg
    33781 ataatggaaa gtatgcatac cttcatacta gaggtgtgat tggagaaagt gacaaagaag
    33841 ttgatatagg tgatcactta agcaattact ttttaccaag tgaaatagta gatatagaca
    33901 gagcgtgtaa agcaagtcta aatctattag aggtagcaga ctatgaagtt actgtaccat
    33961 tattagcatt agtatattta tcccctttac ttcaagctat taaggatgta ggaaagatgc
    34021 cagagtttgt agtatggttg tttggaacaa cttgttcaag gaaaacttct ttagcaagag
    34081 tatttctgag tcactttgga gattttacta atagattacc tgcaacattt aatgacacct
    34141 atgcatctat agagattaag gctaatgcaa taaaggattc acttaactta atagatgact
    34201 acgcaccaaa gcaaactaaa aagcaaaaag atgcacaaga tgaaatcgca gaaaaggcta
    34261 tacgagcata tggagataga atagcaagag gtagagcaaa ctctagtata attagtcaaa
    34321 agcaatatat acctcaagga atgttgttaa tgacaggaga gaatcttata agaggacact
    34381 caactgttgc aagattagta gcattagaat tggacaagga ctcagttaat ttaaagctac
    34441 tcaaggaaat gcaagatagt gtaagtttgt tgggagaaag catgagagga tatatagagt
    34501 ggttgttaca cggcatgaat aaagatagta gtgacattgg aggaattcta atacacaact
    34561 ttgatttata taaagaagaa ttagagaaaa tagagtatac acatacaaaa ggtggtcatg
    34621 gtagaagtat tgaatcatgt gcatggctgc tggtaggtat atcatccatg ttatcatatt
    34681 ttgaagataa aaaagtaata tctgaagttg agtttaatca atatatacaa tttgctaaag
    34741 atactatggt gaatgtatta attaagaata ataatatcac aaaagaaagt tcaccaatag
    34801 atgagttttt atacacgata aaagaagcaa tagattctaa ctctattaag ataagtactc
    34861 tagtagatgg aaataaatta aatgacaatg atgatgatac atatggatat aaggatgata
    34921 aatattttta ttttcatcca gataagacat atagttacgt acaagagata caatcgaaat
    34981 cgggaaacta tataagttta acaaagagag ggttaattaa attattaaga gaacactcga
    35041 taattaaggt agatagtgat ggatctccat aaaagtatac tattaaagta aaagatggaa
    35101 ctgactataa agagaaaaga tctaggctat tacgattagc tataaataca atagggaaat
    35161 tataagacaa taagagataa atggtgatat agaaagaggt aattatatga caattaggat
    35221 taatttagat ggagaaaata tattagaaaa tgtagataat aaattttatg gattaagggc
    35281 acgtgttgac tttgatcttg atttattaga tgaagatgtc atagatatta tggatagaat
    35341 attaacttta gatgtaaatc catcaagaat gtttataaca aaaggtaggg tagatatatt
    35401 ttatcaacct caaaaggaga tttctataga atctaagtta gggtatatga agttaattaa
    35461 tgaatttata gactttatag aatcgcaaga gattgtagaa atgaagtttt taggatggaa
    35521 cctaaatgga gataagattg tagaatcaca agcaaatgat agtaatattt catttagcaa
    35581 agaaatattc aatccagata cagtttatct tgatggactt atagagggat atgtgaatct
    35641 ttagaaaaag ctaagttaga agtatgtagt tctaatagga gctgcatact tacttaatac
    35701 aagattattg agaagttaaa aaaaggaaat tattatggag gagaacttat atgaactata
    35761 ttacaacaca aggatttgat acaataaaaa gggataagat agaaataaaa agaatggtgt
    35821 atgctttaga gaatgagggt gattcgtaca atgttattga agaatgtata tgtactttag
    35881 aagaaaatat atatgtaaat gatgattttg tgatagaagt agaaaatgta tttagttttg
    35941 ttattgatag aataatggac tttataaaag agaagaattt gccaaaaaac aaaatagaac
    36001 atgtaagagc ttatatagat gtatttgaaa atccaacttc aaatacaaaa atagtaaagt
    36061 ctatagatat atatgaagat tatgataaaa gatatattga taataagttg gataagttat
    36121 ttaaaagcat ggataatatg ataaaacccg aatttgttcc agtaatagat ggtaaatttg
    36181 atatacgtgg aagtaaggat ttgaaagagt ataataaaaa attaatgtta gacatagtaa
    36241 agcaaaaaac ttatgaagta aataatggag gaataagaat aaataaatta tctgcaatat
    36301 taaaattagg agataaaagc atagatggca taagcaaaat gatgaaggat gtggcaaatc
    36361 taaagataaa accaaaatca gtatataagt gaagatacag ttgttgtaat gtatatatgt
    36421 aataagagtt gtattgtgct taatatagaa gagtattcca agatactgtc agattttgtt
    36481 gactacataa ataatataga agatatggac ttatatttag atgatagcat tttatatggt
    36541 gactataaaa taaattgtgg agtagacgat agagatataa ttgattttaa ttatcaaagc
    36601 tttaattcaa aagtaacttt gtttgctgga catataggaa acgagataat acaagctgca
    36661 ttatagaaat atacaatcgt agagaggata tagatatgac agaaacttat aaaatcagca
    36721 taggaagaaa agatttatat tctaaagact ataaggcggt tgaaagaatc gactatgaaa
    36781 agaggtatat agttaatata agtagaagct tagtagacat actttctata cttatagaag
    36841 aagggatata aattatagat atggctacat acttagtgtg tagcctttaa tatagactta
    36901 aattagtata tttaaacttt ggaggatata atatgaaatc aaagaaagca gtagtatatg
    36961 caagatttag tttggacaat caaagggatg agtcaataga tgctcaatta agggcaatca
    37021 atgaatatga agataagaat aatataaaaa tagttaatca gttcatagat agagcaaaat
    37081 cagcaacatc agataaaaca ccagaatttc aaaatatgat taagttctgt gaagcagata
    37141 caacaggaat atctatggta atagttcata agctagatag attttctaga gataagtatg
    37201 attcagctat gtataaacag aaattaaaag taaaaggaat aagagttgta agtgtattag
    37261 agaacctaga taattcgcct gaatctctaa tattagaatc agttatagaa ggtatggcac
    37321 aatactatag tgctaactta gcaagggaag ttgctaaagg tcaaaaagaa aatgctctta
    37381 aagctctaca caatggagga gatgcaccat taggatatga tgtagcacat gataaaactt
    37441 atacagttaa tgaagaagaa gcacaagcag taaagattat atttgataga tatattaaag
    37501 gatattcata tagtaagata atagatgaat taaatgattt aggatataag actaaaagag
    37561 gtaataaatt tggaaagaat agtttacatg gaatattgaa taatgagaag tatacaggag
    37621 tatatgtatt taataagact cagagaaaag gtgtagatgg aaaaagaaat ggtcatgagc
    37681 aaaagagtga agatgaaata ataaaggtag aaggtggtat accagttata attgataaag
    37741 aggtatttga acaagcacaa gagatgatac aaaaaagaaa gaaaactcca ggagcacata
    37801 aagctactac tacatattta ttaacaggat taattaaatg tggagaatgt ggacatgcat
    37861 ttcaggggca taagagaaaa gactcttatg gtaatgaata tgtttcatat agatgtggat
    37921 gtagaaagca aaaacgagat tatctagaag agtttatatt acaagaactt gaaaagaaca
    37981 tattaaatga tgaggcaata ccagctttaa gtaaagcatt gaatgagaag ttgaattata
    38041 agaatgaaag taatgcagag ttacttaaaa acttagatca gaaactagag aaggtaaata
    38101 aagagataag taatatacta aatgcaataa tgaatggtat agtaagtagc atgttaaaag
    38161 ataagcttga tgagctagaa caagtaaagt taaacttaga tttaaaaatg aatgaattaa
    38221 agatagaaaa taaagttgtt agatggtgta ggcgtaacag aagaacaaat aagaagtatg
    38281 ttctcaagat ttaaggaatt tgtgctagag aggaacatac ctgaatgtaa gaaatttata
    38341 ggggactata taaaggaagt aatcgtatat aaagatcacg ttgaagttgt attcaatttg
    38401 gtcttttctt ttgtcgatga tgaaatagct cataacttac acattactgt atcaagagta
    38461 aaagtaaaat aaaaacatta aatataaatg ttaatttaaa tgatattatg gatatattta
    38521 acaaataagt agtgttacat gatataatat cacatgtata tgaaagggat aaaatttata
    38581 ctattagtat tggtggtgaa atgaatgtca aaaattgaat actatatgaa tttaccctat
    38641 gatttatcag gatcaatgtc taagaataga tttagaaatg aactactttg gggattgaaa
    38701 aaaatgtatg agttatataa gacgaatgaa gattttgtag tagtttttga ttatagatgt
    38761 gatattgaag ttcatttaga aaataaattt gaattttatc aagtgaaaac tcaaaataat
    38821 tcaggtacat atacgataaa taaacttact gataaaaaaa agggtagtaa atcagtagta
    38881 gggaatttat atagcttgaa atatgatata aatatgaatg agattgatga tgtttatgtt
    38941 gcaattgtat caaatgctcc tttgaacgat ggtaaaaaaa catataataa ttctcatgaa
    39001 gttaaaataa aaacaataga tagtagcgct atagaaaaga taaagttaag tataaaaaat
    39061 gacttaaata tagatgaaga tataaattta gaaaatttat tttttattag aattggttta
    39121 gatttaattg aaccacaaaa aactttaatt ggtgaaactg ctatattttt tgaagatgtt
    39181 tttggaaggg aatgtagtaa agtaaaatca ttatacaatg tcttatatga agagatatat
    39241 agcaaatcag catatgagtt agatataaat acgtatgaaa atatagtatc taagaaaggt
    39301 attaatagag ataggatgga tattatatta aaaagttatg ctaataatac agataagtca
    39361 gtagaactag caaaatatag tataaatgaa tggtgcagga ataatttctc acgtagatta
    39421 tctttgataa aatcattaac tacaattgta tctaaattaa gtgaaagtag tattttaaag
    39481 gatatagaaa actgtatatt gtcatatata tataataata tagataaatt acaagtatca
    39541 gataaagagt taattgaaat tataagtgag atagtagaag aaaagaggcc tatagaagtt
    39601 agcaagacag atatagaagc tcttatctta ctaacattaa aaaagtatga ggagggtgtt
    39661 tatgaatagt ttgtttgtga acagtctata tatatttgaa tatgaaagta aaatggcgaa
    39721 gaaaatagac tttaaacatg ggattaatat attaacatca gatgaaaaga gtggtaatga
    39781 cgtaggaaaa tcagtactat tgaaaagtat ttatcacact ttaggagcag atagtatatt
    39841 tgatcatatg tggaataaaa ttacaaaaac atatatatta aatgttacta taaaaaataa
    39901 gacatactat gtatatagaa gagataattt atttaaaata tataatacga attttaaaaa
    39961 aatatttatg acaaataacc gtgatgaatt atctaattat ttaagtgatt tatatagttt
    40021 taaggtaatg ctgccaaaaa gagaaaatga agaattagag ttagcacctc ctgtatatag
    40081 ttatttgctt aactatatag atcaggatca tttagatgga tctaaatttt catcttttaa
    40141 ttcattgaca caatttccta actataagga aaatgtaatt tatactcatt ttggactttt
    40201 tgatgaagag tactataaag ctataaagga gttagaaata ttaaaatcag aagaaaaaaa
    40261 taagaaaaaa gaacgagaag ttactttgaa tatgctaaat aaaataaaaa gttacttagg
    40321 aaacttagat gcaccagaaa gtatagaagt tttaaatata gaattaaata aaactaaaga
    40381 agaatattcg aatatagtta taaacttgca aaaaataaaa aataatttaa tgaaaataag
    40441 gaatgaaaaa gtagatttag aattaaacat aaaagaaatt gaattaacaa gaaggaatga
    40501 aatgaagaag ttaaaagtta aaaatgtgtg cccaagctgt tcacatgaaa tagaagatat
    40561 agattctaaa tttataataa ataatcaaat agaagatctt attattctta aagatgagtt
    40621 agagtcagaa attataaagt gcaatagagt tatagaaaag aaagaggaag aatatcaatc
    40681 actattagat aaacttcatg agtatgagtc aaatatgaaa ataaatgatg atagcatatc
    40741 taatgtctta aagcataagg catatataga tactaaagat gatatagttt tagatttaga
    40801 aataatagat aagaaaataa aagaaataca acagacaata gagccatatg ataaaaaaat
    40861 aaaagaatac aacagtctta agaagaaggc aaatgctaag tatgaagagt taatgaaaaa
    40921 ggctaaaaaa gactttggat tagaagagat agatgaaaat aaaataaaaa atataaaaaa
    40981 taactttata gcaagaggta gtaatagagc aataactact ataatgtggt atctgacatt
    41041 gttagcagta aaatatgaat ttaatgaaaa tgcaataaag tttccactaa ttttagatag
    41101 tccaaataat gttgaatctg acgagataaa ggaagaatca ttgtttaaat atatatttaa
    41161 aaatactaaa acagatactc aattaatatt atcatcgtta gggttcaatg aaatgcaatt
    41221 tagtgaattt aagtttgata atataataaa acttgaaaat agcaaatata atttattaaa
    41281 taaagaggat tattataata atatagatat tttaaataaa atatttgaaa attagtatag
    41341 gaatcgtggg tatgatttct gtgaatcgtc tccaccattg aaatccacga aaacacattg
    41401 atattttatc aatgtgtttt ttaagtaata gggggaaata tgaaagatag atttaactta
    41461 aaaagaaaaa gtattcagtc attaatgaat aaaaatgtag atgtttattc ttgtaaagat
    41521 tgtatagatg attttataga atcaaatttt aaaatttata gaagttatta tatatcagat
    41581 gatgatatat tagagattat ggatggtaca ggagaggact acaaggatgt tatagcagat
    41641 atgttaccag acaaagcgca tataaaatct ggagaatttg gtgaaataac agcaacagaa
    41701 atatataaga gcaatataca aacaacagaa atatatatag ttgataaatt aagtcataca
    41761 agaaaagagg atactaaagt tgctgcacat aaaacagata ttttaattat tgaaaaaacc
    41821 tcagaaggtt ttataattca ttcttctgag gttaagacta agataactga ttcagacttt
    41881 aatcctattg aagcaatgat agagggggta aatgatgata tagttacacg tgttgcagag
    41941 acactgaatt ggattcaaag aaaactgaaa acagaaaaga aatttgatga attaaaattt
    42001 ataaaacaag taatagagag tatagaaaat caaaatgtag aaaatgaata caatggtgca
    42061 gtttttatag atgaatcaaa attagactac gagataaata aaaatatcta ttgtgatgtt
    42121 aagctttcta aaagccaaaa aggcaaatat gacaatgaat taaagtctat aggatgtgtc
    42181 atagatggtg ataagattag gtttgatagc gtgaacatag atgatattaa taaactaaat
    42241 attaatagtc gtaaaagaaa ttcaatagaa aaattatata ataaatctca aagaaaacta
    42301 gaacatatag atgatattaa aattcaaata gtaacttttg atgatattaa taaacattgt
    42361 ttagatatgt atgagaaaat tattcatgta gggagaatat aatgagtatt aataataata
    42421 taaataagat taggaatctt gatatacaat tagcaaaata tgattgtata tcaagaatgt
    42481 ctgcaaaaga aacatcgaag cattatatgc gattatactt taaatttata aaattattag
    42541 aactatatga agatagtagt ttaaatataa acaatggaga atacttaaat ctagctaatg
    42601 acttaataat attttctaaa tatgatatgt cgagtagatt taaaggaatt gatgaggaaa
    42661 gaaacttagt atatatagca gttatatatt acatattggg atatagattt gagtgcaact
    42721 taatattaga tatattagat atgcatgata tagaaaatga atatttaaaa ataataattt
    42781 atttaattag aaataaatat tataaatgtg atgtactatc ttgtataaaa aaatattata
    42841 tagaagatga gagtaattta agtttaataa taaaaacttt gtatgaaaaa gagcttgtat
    42901 gtgatactaa agatcagacc tatatacaaa ttattattgc tatattaaga aatatacaaa
    42961 ataatggatt ctatagagtt atttcaaaaa aatcaaaatt agatataaat atatggagaa
    43021 aatttgtaca acaaagtata aagtatgatc aaatcatata tgatcttccc aaatatcatt
    43081 atgatttatt aaatgatgaa ttattgaata taaagcatgg atatataaat atgcccacta
    43141 attactctaa gatagaagta attaagatag taatatttaa ttatttacat acatatcaag
    43201 ataaaaaaat agcatatata catgtagaca aagatgatag ggctataaat gcaattaaag
    43261 aatattttac tgaatattca acaagaattg aatttattga aatagattca attaataatt
    43321 atagtgagat agctactgat aacaatttta taatcataga tgattttagt aatgtttcaa
    43381 acaaatacta tggtacacga tttgaaataa tgatatcatt agcattaaaa ttagaaaaaa
    43441 ggctattagt attgaataat aattatctta aaatggactc taatcaactt gaaaatataa
    43501 attataatga agatattaat agatatagca atatagttaa ttactatttt aaagatggaa
    43561 aaaataaaga gcttgaaata gaatatgaaa aagagagatt tgttacagaa agttatttgt
    43621 taaataagga gataaataac aaaataaact taaagggtat taaattgaac agtgcaggag
    43681 ataaaagttt actatctgca ataaatttaa tatctaaagg atacaaagta tcaatattta
    43741 taccacagaa aaattctgca aaaagtggta taaataaaat atgtataaag ctattaaatt
    43801 taattgatag gcttaacggt aaaatattgt acgataaaaa ttgtatagat gattcaaact
    43861 tattagatag agcagagtta ttgttaggta gagaaagtat atatatgaaa ttatttagat
    43921 taggggtaat tgtaattcat tctgatatgc ctcaagaagt aattgaatat atgagatatt
    43981 ttatacaatg tggaaaatat aaaattatca taggagacaa gattttaact aaaaacttaa
    44041 gtaaatacac agatgtgtta attataaata gtattagaat aaatatagat aaatcatggt
    44101 ctattataga tgatagatta ctattagatt taattaacga tttttcagat cagattaaca
    44161 aaaagcatat aataattagt aattataaac aaaaagatat ttacaaaaca aaaattaaaa
    44221 atattaaaaa aggattaata ttaaatagtt ttatttctca atcattacat aatatagagt
    44281 tatttaaatt aaattatgaa gaagaaatta ataatatatt agatagtata gagtataata
    44341 tatgtgaata tatattatac gattattcta atgaattttt agataattta atatatacaa
    44401 ataatcaagt ggattttatc aaagaaggac agtttgtaaa attattgaat aaaaaaatag
    44461 acaaactaaa atcattaagc aaggataaga tagcagttat atacaaatca aaggcaaatt
    44521 tatcgtgctt agatatgtat attgatctaa aaaataaata tattaatttt gatgatatag
    44581 agttgattaa ctatatattc tataattata tagttgtaaa taaagaatat gttaatatta
    44641 taagtaatat agagtatatt tataaattaa atataaatga agatggcata tataatataa
    44701 tattacattg gataagtgaa tatgattata atgatattga tacattaact aaaattaata
    44761 accttgaaat aatatttact gttatagaaa aggtagtaag aggtttgttt gttgaaatgc
    44821 tatgcaaatt acagaatata tgtaagatca atgacagtac aaaattacat aataaattac
    44881 aatatattaa agatatatta tataatggac ttaaagaaaa tatattttta gaaaaactaa
    44941 attataaact actagataga aggttaacga aaaaaattaa tttatatatg aaaaaaaatg
    45001 ctgaattata tgaaagtaga gtggaaacta tactactaaa tattagagaa tatgtagatt
    45061 tagatgagtt tgaattattt ataatagata agctaataca aaaaattaaa taataaatct
    45121 aatcgtaggt gttatcccta tgaatcgtat ccaccattga aatccacgaa tacctatatc
    45181 caattggata taggtatttt tatacatttt tagtttaaat attattgata aatacattta
    45241 aaaagtttta acctaaagtg aataatctaa ataaaaatac aatactagga gaggtcatca
    45301 ttacaataac agcttgtgat gatgaaaaag aaatacaaat cgtaataaaa aatcaagttg
    45361 ataatatatt aaaaaataaa aacaaagaat attgaattaa aaaaatatag ctcaaaagaa
    45421 gaaccattac aaagttaatt gagaggatac actactctta gatataaaaa tggcagaact
    45481 aaatagtata gatatcgcaa gaaacataag aaaagtagat aataatattt ataacatctc
    45541 taataaatta tgtacaggaa agatatgaag taagagctta tcgatactta ttaaagccaa
    45601 taaattttta agaactagaa aaacacatat taacatatat caaaaaaatt gaaaaaaata
    45661 aaaataagtc taacacatac aaaatctaat ctagcaaaaa aatatataga agttcaaaaa
    45721 aagaacatgc taatacatac aaaaaataaa acttttgatg ctatatgtaa gagaaaatag
    45781 aaaaagattt aaatatagag gaacttgtaa gatgtcataa aagttatata attaacttaa
    45841 actatgtaga aaatataaag tcaaatactg caatattaga cagtcaagaa taagtaccta
    45901 ttagtagata tagatataaa gatataaaag agaggtttct aaaatttatt ggtgatagaa
    45961 tatgctaaac catataaata aaatattatt aatattatca ttgtttacac caataatgat
    46021 actaaaaagt atattaactt acgataaaga tacagataag actaagaaaa catctttttt
    46081 tactgtatta ttaacttatc ttataactaa aatcattata ttatttgacg ttgataagac
    46141 ccatgattat aatatgaaga aaaatctata tgatataatc tattatttga tatttattac
    46201 ttgggaactt actataatta tttttataag ataggaattg ttaaatatat agtttcattt
    46261 ttcttatttg acgtatatca ccctttaata aaagatgtta tatctataaa tttatttttt
    46321 gtagttacaa gtaatgtaat atcatcagag gaagctctat tagtgtttag ttatgataat
    46381 gctaaagtag atatatacta ttatcttata ataataatta tatagtagct tgtgccatat
    46441 ttaaatttat taataaaaga ttgggactag ataaagagaa taaaataaac tatatatact
    46501 tatctgttgc tttaataaca aatttattta ctatattaat aatttatata aatagaaaaa
    46561 tgtatcgatt tggtgggtat taggaaatat atatagttgg gtatattgta atacctaggt
    46621 taatactatc tagtagctta gtcattatta tagtgtttat aaaaataatt aaggaaaata
    46681 agttgaaatt gcaaaatgaa gtaataaaaa ataagctaga tatgcagtat tctcattatc
    46741 taagtattca agaatcacac actaaagtta agaagcttta tcatgatata aataatcata
    46801 tatattgtat agaaaatctc aaatataaaa aaggaaaatt gatgtgtatg taaatagttt
    46861 aaaagattaa attaaagaat ttaaatcaat ttacaataca ggtaatgtta tattggatat
    46921 aataataaat gaaaaaagtg atgtaagtga aaaaagaaaa attaaattca tttgtgatat
    46981 caatttttcc aaagtgaatt ttataaaacc aatagatgta tctaatatat ttgcaaatac
    47041 ttagataatg caatagaagc ttgcgataag atacatgata aaagtattga taaatatata
    47101 caaataaaag gaactatctc aaagtcctat ttcgtaatta aatgtgagaa tagtaaaata
    47161 aattcaatta gaaagaataa aagtttatta ttaacagata aaaaagataa acttgtacat
    47221 ggaataggga ttcaaagcat caaatcttct ataaaaaaat atagaggaga tttattattt
    47281 gaagataaaa aagacaaatt tatattgaat atttatatac cattaaatca aaattttgat
    47341 agttgggtcg attaacctac cagttgggga acatatattg atactaaaca tatagggatg
    47401 ttatctttta atagaaagag atagcgtctt ttttttatga gaaataacga gttttcaata
    47461 tataaggagg attatatgaa gataaaaaaa ttacaataac tatggttata gctataagct
    47521 taacactagg tttaataaca ggatgtacaa ataaggtttc ggatacaaat gaaaaaatat
    47581 atactattga acagatttct agtatcaaga agacttgtca aagaaaatat cagaatcaat
    47641 agaaaatagt ggtcttaggg tagctgaaaa taaatcagat ggaagttttg ttttgtcttt
    47701 gggaaacttg gagtatacaa aagaacaatc tagccaagtt ttacattatt caatgactaa
    47761 ggacaagaag ggtacgaagg aagtattatc aattcaatgt gttaaagatt tttcttataa
    47821 tgaaaagctg tcagaagatg ataaattcat aatggctatt tataacatat agatcattga
    47881 ttcatgtaga aataagtgag aaagaatttt ttagaaaaat tgaagaagta tttgataaag
    47941 gtgaaggaaa tatagatgtt gataatttgg gagatataaa aattcaagtt aagaaatttg
    48001 atgataaaac taggtcttta gaattaaaac ttattaaaga atttaaattg aagtaggaag
    48061 attcactatg agaaaataca aagctatttt attaacttta attacaagca ttgtagccat
    48121 aataggattt attatataca acaactattt tagaaaatgg aatgaagctg aaaaatatat
    48181 aaataaatat atgacatatc aaggagtttc aggtgatgat atagagcgta ttacaaaaga
    48241 aaagtataca aaagagaatt atgatggaat actttataaa tcattttaca aaaattatcc
    48301 aagttatgaa tactaatatt tttatagtgg tgattattat gcactacatg taaataaggt
    48361 gatactgcaa gtttatcatg aggaagatgg tagtaagctt caaaaaataa tgaagaatta
    48421 aaagatttaa aatatccacc aatctactta acagatgagt tggataaata atttatagta
    48481 aaataggagg attatatggg gatttactta aaaatgtcac tagcatattt aaagaaaaat
    48541 aaacttagaa cactactttt aataatagga gttatgttag gtgttatgtt gatatttgga
    48601 cctagtgtta taaaagattc acaaaatgaa aacaatgtag tagcaataca tgaactttac
    48661 agtggatacc atgtagagtt tagtgatttg acacttgatg atgctaaaaa attagaaact
    48721 gatgaaaaag tatcaaaggg taattcggta caaaatctag ggcgtatttc agataaaaaa
    48781 ggaaactcat ttatattaac ttcatcaaac gaagagtatc taaaaagtag atacaacaaa
    48841 ataatagaag gtagactacc taaaaacaac aatgaaatag tactagagaa aaaagcactg
    48901 gaagcaatga atttaagtga aggagtagga tctacattaa atttaacaat aaaaaagaac
    48961 tataaagata ctaacggaag taatcaatta ttttctataa ataaagaatt taaaatagta
    49021 ggagttatgg aaaaaccaaa agggtactat gatgtggttt ggcaatacga agcagtaact
    49081 tatggcaatg atgaaacaaa caacattata cctaatgatg cgattagtta taatagtata
    49141 ttaagtttta aaagtggatg gagaaatatt gaaggtgaat gtgattatct tatgaaaaaa
    49201 tataagttag gacaaaaaag ctttctacca aatgtacctc ttgtaaggga acttcgttat
    49261 gtagaagatg ataagaatga tccgaatgtt tttaaaagaa atgttttaat aactacagta
    49321 tctataattt tcatatttaa tattttcaat attacactaa atcagtcggt aaaagaaatg
    49381 ggactgctta gactgatggg cgcaaagaaa agaaacgtaa ggtgtatgat aatctatcaa
    49441 gcattaatta taacaataat aggtatacta cttgggttag tagctggggt tacatattca
    49501 tatataggaa ttagtaatta taacgaagtt ttatacagtg aagctggtct taaccctaaa
    49561 ttatatataa ataatgaaat agttataaaa gctatattgg ttggaataat ttctgttttt
    49621 atatcttgta ttataccaac ttttaaaatc ggcaagatat cacctattga atcaataata
    49681 aatacagaca aaattaaaaa tcacagaagt agacttggaa tagacagatt agtaagtaaa
    49741 atatttggat tttatggatt tatgggactt aaaaatatcg gaagaaataa ggttagagct
    49801 gctatatcta tgttgtctat tgcattagga ggatatatat tcattactac attctcaagt
    49861 atgcaagaag aggtcaacag taaaattgaa gatatgcaaa atagatataa tataacaatg
    49921 caatttggag taaatgcaga cccgcaaata tcaaaataca cagatagtga tgtagagaat
    49981 atagaaaaaa ttaagggtgt taaaagtata tataaaattc aaataacaaa tggaatgttt
    50041 acttttaata ataaggatat aaacaaagaa tttacaacct ataatggagt agaaaaaaaa
    50101 gagataatgg aagataaatt agttttaaag ctttatgatg atgattatat agatgaaaag
    50161 ttaaatgact ttgttgaaaa aggtagatta gatgatatta aaaaggacac tgatggatat
    50221 ccaaatgtag cagtatataa ttatttttat gatatagttg atgatcatac tataaagcct
    50281 atattcaaag aattaaatat gggagacata ataactgtaa aaattcctgt tgaagaaaat
    50341 aatacaattg tttataaaga gaagaaggta agagtggctg taattttaaa ggatgaatgg
    50401 attgctatgg gagatggcga ttttatgcca gatctagaaa ttataacaag taatattcac
    50461 tctaaaaata taacaggaga acaaaaatac actcaattag gtataaattt agaagatcca
    50521 tatgatgaga ttgttaataa tgagatacag aaaatttcaa gaagtatacc agggtctcta
    50581 tttaatagta gattaagtta tcatgaaatg tcagaaagta tatataaaag ttacattaaa
    50641 tcacaaatag caataattgc actagtctta ataatagcat caattaatat tttctgtact
    50701 ataagaacaa atctactaat tagaaaaaaa gaaatttcaa cgcttagagc attaggtgtt
    50761 agtcttaaaa atatgaaaaa aatgcttata tatgaagcat tagcatatgc agtttttagc
    50821 tttataatag ctatgattcc atcatttata aatctagtta aatttacaaa ttggaataat
    50881 gatgcgtata taaactatgg agtagagaat tttatgtctt ttacattccc aattaaggaa
    50941 tctttactat tctttgctat atctgtattt gtatgtttaa tagcagtagt tgtaagtaat
    51001 agagattttg aaagtatgaa tattattgaa ggtataaaag agaatgaata atttgggagg
    51061 taaatgtatg aagatgttaa aagttataga tattaaaaaa atatatggaa aaggagaaaa
    51121 tgaaataaag gctgttgatg gaattacttt agagatagaa ccccataaat ttagtgcaat
    51181 aattggacaa agtggttctg gaaaaagcac attacttcac tgtatggcag ggcttgataa
    51241 accaacttta ggtaatgtat ttatggataa tttagattta tatactttaa gtgatgaaaa
    51301 gctatctaat cttagaagta aagaatttgg gtttatattc caaaactata atctaatacc
    51361 tgttatcaat gtttatgata atatagttct tcctatttta attgctaaag gaaagataga
    51421 taataattat attaatgatt taataactaa gttaggatta gaaagtcaga ttaataaatt
    51481 tcctaatgaa ttatcaggtg gtcaacaaca aagagttgca atagcaagat cacttgccaa
    51541 taagccatca ataatttttg cagatgaacc tactggaaat ttagacagta aaacaactaa
    51601 tgaggtgatg aatttactaa agtattgtgt aaatgaatac aagcagacgt tggttatgat
    51661 aactcataat gatgaaatag ctaagatggc tgattgtata ataactatta gtgatggtaa
    51721 agtcatataa aatgtattgt ataaaggttt aatcgtgggt attattcttg tgattcttct
    51781 ccaccattaa tccacgaaaa aaggactgtc gaatgagtaa ttttaaattg ctgtgcgaca
    51841 gttctttttt tacttgcttt tcattaattt atatttatgc aaaatttgag cttaaaaacg
    51901 gctataagaa ataaaggtat aaaaatacca ttttaaaata gaataattta caaattgtaa
    51961 gattaaaaaa tatttttgag aggatgaata tacatactac atttattaat gattatctta
    52021 tttgtgaaac ttagaaatac tataggctaa cactacaggt ataaactctg aaagaatatt
    52081 ttgattgcct ctgattagaa ttcttttaaa gctcatacta tgttttattt gggtgaaagc
    52141 tccttatgcc tgaatacttc tattcattct aagttcacat ccttgtgtac cagtgattct
    52201 ttctaaatta tcttaatgcc aaaatcttgt tcgcatttca aaataaagtc aggtagctac
    52261 ttcaacattt tagttatatt tcttcaatag tttgtctcca aacaaaggta catctattag
    52321 caacagattt aattttattt atatcaataa ataatatata ctttgaaact tcattaatat
    52381 caccaagata atttataagt taaactatta tatactatct tcaccaacta catcctccat
    52441 agttttacac tttcttaatt cagcttggta atctaaatct gtaataatta tttctctttg
    52501 atttttcatt tctttaccta caaaagttta atatgaatat tattccatac ttaccaattt
    52561 tacgttcaaa aaagactgta ggtaagtctg catttacaca aacctactta tcagtctctt
    52621 tttttgaaat taatttagca tgaactatag tacgagcatc tttaaattca tagttacaag
    52681 tatacaaagt tataatttta tctgaaatat ctacctttat atcagatttg tgtgctgatt
    52741 tttaggttat ataattcaaa gaatctttaa actcataatt attattaaag tgtatactta
    52801 aataatctct gttaattaag tcagcagtat atactgaaaa aatttcataa gtataagttt
    52861 gtactttata atttatttct actaagttat tttctttgaa aaatacttca tcagtatagt
    52921 tttctagctg accaaacata gttttatttt tcatataatg accatagact attaaactct
    52981 tatcattttc aaaattattt ctataatcca tgaaaatact acctaaagga agataatttt
    53041 tataaaaatc atgagttagg tagaaatcat tgttatatcc ttgtactaca ggatagtcta
    53101 tatttacgtt gtttatttta agccagaatc tataatcatt atttttatca taaagttctt
    53161 gatgtttgct attattgata gtgttttctc tgagttctgt atatacttca gcagcttttt
    53221 tatattcaga taattttatg taaatcgaaa ggctagagaa agttagcgca ataatgcaaa
    53281 taatatttat taatattttt actagttttt tcaattaatt accccttgta ttattatata
    53341 aaagattaaa taaattttat ataattaaaa tttttattgt agttatttag caaataatga
    53401 atacttataa tatataaggt tgaaaaaaac agtatattca ttgacaaata taagttttaa
    53461 gtatatatta aaaattatta gagtgtatat aaggatgtat acagtgtata ttaagaatta
    53521 ttagagtgta tataaggatg tatacagtgt atattaaaaa ttattaaggg gagggggaat
    53581 ttatgcaaca aaaatgtaaa aagaaagcac tatcaatgat tttaagtatc tcaatgggac
    53641 ttggatcagt agcatcattt aatgcgtcaa atactttcgc agatactata gaagaaagta
    53701 ctaatgcagg aaatgcagaa ggagatacta atgcaggaaa tgcaggagag gatgctaatg
    53761 caggaaatgc aggagaggat gctaatgcag gaaatgcagg agaggatgct aatgcaggaa
    53821 atgcaggaga ggatgctaat gcaggaaatg cagaagagga tgctaatgca ggaaatgcag
    53881 aaggggatgc taatgcagga aatgcagaag gggatgctaa tgcaggaaat gcagaagggg
    53941 atgctaatgc aggaaatgca gaagaagata tgaatgcatt agttgtagaa gaagccactg
    54001 cagaagatcc tacatctgta ggagacttta aaattagtgg tggagaaata aatgtcgatt
    54061 ttaaatttgc aagtggcgtt ttaactattc ttagtggaaa acaaatgaca attcaaaata
    54121 ataatccaaa tactccaaca acacatagga ttgttatacc taaagatgta aaagctgaat
    54181 taatatttga tggagtaaat attaaaactg catctaatag cccatttact ttaacaccag
    54241 ataaagatgg cggtgcatat gcacatgtta tattacaaga tggtagtgaa aacaaactag
    54301 agtcaggtga tttatattat ccaggtatga gagcaggaaa aggtactact ctaattattg
    54361 atgattctgt tgtaaataga gatattgaag gagagtttat agttcctgag ggtggaaaaa
    54421 ttcctagaga tgtaactcta gaaaatggag acaagttaaa aaaaggagat cgccttacac
    54481 tactagatag taataataga ggaagtttaa aagttgttgg aaattattat tctgcaggta
    54541 ttggtggtgg aaatactgaa agtggaggaa atattattat taatggtggt gctataactg
    54601 ctataggtca agaatcgagt cgtaatacag gatatggagc tggaataggt ggaggcggta
    54661 atggtagtgg tggagatatc acaatcaatg gtggtactat aactgctaaa ggtgcatacc
    54721 atggagctgg aataggtgga ggatactata caacaacaaa gaatgcatta agtccctcag
    54781 tagtagatcc tagcacaggt tctggttata gtggaaatat tacaattaat ggtggacttt
    54841 cctattcata tggaggtgca catggtagtg catttgggga tggatgtgtt aatccaggaa
    54901 caaatagagg atatcgtata cttgtaactg gaggaacgat tttaccttat atgacaggag
    54961 tgggagattg gatttttgac ctaagtgcta caacgggaga tgttatagta acaggtggtt
    55021 cattaaaagc aacaacattc aaaagtttag gtggagcagt tgcatacggt gatttagaaa
    55081 agaaaacaaa agtttttatg aataaaatat ctttaaagta tttaggacaa gataaagtta
    55141 gtactacatt agttgatgat tttaaaatgt taattgatgg aaaaatttat ccttatggag
    55201 cacctagtta tacagatgat caaggggttc tttacttatg gttttctgat caatttaagg
    55261 gatctgaagt atctgttaat ttagttgtta tagataaaat tactggagga aatataaaac
    55321 cagatgattt ttatgttaaa gatataggtt caggttctca atttttaaag caatatgaag
    55381 aatttactat tgatgatact ccaccatatt tgattattaa aagatatgat ggattaccat
    55441 ttgaagaaga tgtagaaaaa tcatttttag attggatatt aaaagatggg ggtattccaa
    55501 taattactcc taaaggtgaa aaactcacag ataaaaaatt tatgactatt agttctcaac
    55561 gtttaaatga ggaaacgatg gaaccagata caaatttagg aagtgatgac cttacaaaac
    55621 aagttgatgc tggaaaatat caattaagca ttacatcaac acagttttca aatgtatatc
    55681 cttttaatga agcttattgg gggcatagag catattataa ggcagaaatt attcctgctg
    55741 atacagaaac ttcattagtt gtagaagagt ctaaagctaa aactgatgtt tttaaaccaa
    55801 cagatacgtt tacattaaat gttactattt caccagataa gaaagaagga ccagattgtg
    55861 cctctccaag aggttacgta caattctata ttaatggaaa ggaatataaa gatccagtag
    55921 aattaaaaac tcataataag ggtagtgaga gtcataatta tagtactgca tctattgaat
    55981 ggagaccttt agatagcaat catcatattt ttactactga acaaactatt actgtaaaat
    56041 atattggaga tgatataaat tacattgaag gtagtgagga tgaaaagaag ttaaagttag
    56101 atatgacaaa tgtagatgta gatggggatg gaataccgga tataaatata gacactgatg
    56161 gtgatggaag gccagatatc aatatagata cgagtggtga ttggaagcca gatattaaca
    56221 tagatactga taatacaggt gaatggaagc ctagtacaga aggtgaaaat ggagatggta
    56281 tttggaaacc tgataaaaat atagatacca atggagatgg aaaccctgat acagattata
    56341 atcgtccagc aatagataca gataatgatg gagtagatga ttattggaag cctgataaaa
    56401 atgtagatac tggctcagga ggttatgata caggtaatcc aaatctaaat aagccagatc
    56461 cagataatgg aggaaatagc aaaccggatc cagataacgg tggaaatagt aaaccagacc
    56521 cagataatgg aggaaatagc aaaccagata tagatacaga tggggatgga aaaccgaata
    56581 taaatataga cacagatgga gatggaaaac cagatataaa tatagataca gatggagatg
    56641 gaaaaccaga tataaatata gatacagatg gagatggaaa accagatata aatatagata
    56701 cagatggaga tggaaagccg gatgtaaata tagatataga tggagatgga aaaccggata
    56761 taaatataga tacagatgaa agtttagata gtaatgtagg tcaaaatgta caaacaggag
    56821 atcaaagcaa tataatgcta gatttagcat taatgttcat tagcttgttt tttttaatta
    56881 aaaatctaac aaataaatac ttaagacgta aataacattt attgtgtaca tatttatttt
    56941 attattttat tggataaact atagtgacta tagatagatt tgtgtaaaca aaaatctatt
    57001 tatagtcatt tttgtattta actttaaagt tttgaaataa ttttcatata gaaaagaaaa
    57061 ttttttatta aaagggatta atgggattga tatcattaat tcaattttag taattatgtt
    57121 tagaaaatga ttttaatcta tgtatagttg tttttgttag aataataatt tgtaaataca
    57181 agccaagcac tcaatattat gttgagtagg gaaatatgat tgtatattct tcagataaaa
    57241 atttgaattt gaagtgataa ttggtactaa tttatggagg ttatgttaaa aaatcataga
    57301 ttctattagg tgattttttc agttttataa aaaacaatac ccatctgata taaaaataga
    57361 tttttttaaa ttaatatctt ttatactatt aaaccattaa agatgatagt ctttcctcat
    57421 aatatattta tggaagaaag aagatttaga cttattgtaa taatattcaa gggaggtagc
    57481 tgaaaatata tcaactaaaa tagatatact actatgtaat ttaatggata acttaactat
    57541 agaaaaagac tatctataaa tatttgaaat aaatcttagt ataaattatt agcagtttac
    57601 taatgttttt ttgtaaaaaa tcaatcagaa gttatataat aactttatat aacaaataga
    57661 aagaggtgaa actacatggc taaaattgac aatatgatgt ctatactgtg gatgttaaac
    57721 tctgacaaaa aaattacagc aaaacagata gctgaaaaat tagaaataaa tataagaaca
    57781 gtgtaccgat atattgatgt actttctgcg agtggagtac ctataatttc agatacaggt
    57841 cataatggtg ggtatagcct tttaaataat tttactaaag cacctctttt ttttgatata
    57901 gaagagcaga aatctctact tcatgcagct ctatttgcta aaaaagaagg atacttctta
    57961 gacgaagcat tagataaagc gatattaaag ttaaaaatgt attcaaatca aaaacaagaa
    58021 gatattttaa caaaccactt aatagccctt gaagtaataa aaccaattgg gaaagtatct
    58081 atagaatcag tacttaaaaa attggagaat agtatattaa aggagctatc tgtagaaatc
    58141 aactatcatg caggtcgtaa agtaagatca aaatatagaa ttataaatcc atatggaatt
    58201 gttcactgga ataataattg gtacgtagtt gcattttgta atatgagaaa tgaggttcgt
    58261 agtttcagag tggataggat tagtgaaatc atagaaacat caaatacatt taacagaccg
    58321 acagaatttt cagcaagtga attttttata aaagggattg tacctgaaat aaaagatgaa
    58381 caaaatataa ttcaattagt tgtagaaggg agtatagatt ctttagatag tttaagccaa
    58441 cattggtttt tagggcacta cttgaaagaa agaacaccta ataaaataat atttatgatt
    58501 gaagaggaag taatatgcaa gtacatacca aatatacttt taccttatag aaagacaata
    58561 caagtaattg aaccactaag ccttaggaag aaaataattg aagatttact agaattaatt
    58621 gagtattatc aaatttaata acttaactga ctgaatatgt cagttaagtt attttataat
    58681 tagatatata aattaattac ataaggagta aaaaagatga aaaatagaaa agtatatatg
    58741 tatgtatttg atactatgtc agattgggaa gtagcatatt taactgctga attaaataca
    58801 ggaagatatt ttaaaaaagg attaaaacta ctaaaagtaa ttactgtagg aattgataaa
    58861 aatcctatta taacaatggg tgggttaaaa gttttacctg aaattacagt tgatgagttt
    58921 aatatggaaa gtaaggattt attaattttg ccagggggaa atacttggtt atctatgaat
    58981 catgagataa tattagaaaa agctaaagaa gctttaatac aagattctat agttgcagcc
    59041 atatgtggag ctacattagg cctagctaaa aaagggctat tagattttag aaatcataca
    59101 agtaatgact tagagtttct taaaatggta ataccaaatt actctggaga aaaatattat
    59161 aaaacggaat ctgtagttag tgatgaaaat ttagttacgg cttcaggaat tgctccgttg
    59221 gaatttacgt ttcaagtatt gaaactttta gatgtttttg aatcagaagc attaaattca
    59281 tggctaaatc tttacaaaac tcatgactca aaatattttt ttgaactaat gaattgtaac
    59341 aaataaattt aaaatttatt ttcaatttaa tatggtatag cattgtgata taaagaacaa
    59401 aaaattacaa tctggtggaa tagagtagta gtttctaata tagatttctt tttgttgaac
    59461 ttaaatttta tttaaattta aattctaaac cactttctat atagccaata taaaagtgtt
    59521 aaaaaattat catatatata attactactt atagtaacac aaatagagct aataactcct
    59581 ataataaaat ttatcattag ttacatatag aataaacctc agttttgatt actgtgggaa
    59641 ctaggattat atgaagctac cactcataga tttcagtttt ttctgttgta tcatagcata
    59701 gaatagtaaa ttcatctgaa actttatttt aaatttagaa tttgcatata gataaattat
    59761 gggcattatt ctgataattc gtctccaata attaaaaaaa gaatgataaa atacttgaaa
    59821 atactagtct ttattgacta gtgtttttta tttcagtgat aaaatctacc aattatactt
    59881 cagttacaga aaatgaggtt ttgagggtat attgggatgc atttaggttg tataattata
    59941 aatttcaatg ttatatgctc attagaataa tagttagtaa atgatatgat tgagataata
    60001 gatgcaataa actaatttag tactgtattg tagtgtttat tataaaatct tttataaact
    60061 atatttataa agatattatt gaatattttc aatattctat tgcaatttat ttggaaaagt
    60121 tatatattta taacatgaag tgttataaat atataacttt taaggggtga ttttatatgt
    60181 ctaaatcaga gcttggtgtt aaaacaaatc ttgtttcaga gttacttatg atatcctatt
    60241 tttttataga ctcattatta aaaaagttta tttttaaaga gggaaatatt tgtattactt
    60301 ttataatttt attcgctttt tgggcatgtg acttcatgta taataaaaaa tataatgatt
    60361 tagttgatga ggcgtcaaag cttatgttat taaaggttga tcatattgca tcaaaaataa
    60421 tgttatattc tatttttcta atagctgttt tcttttcagc aaattataca agaggtttgg
    60481 atatatcaaa tttggatata ggtgtaattc tcttagctat tttatttata caatctttat
    60541 ctaaattaat tttgtatata cattttgata gaaagggaat atgcaactaa gtgataatat
    60601 tgataaaaac gaaaattaaa gagtatagag aatataattt ttaaggagtg attttatatg
    60661 tctaaatcag aaactggtgt aagatcaaag cttatcctgg agttgcttgt aataacttat
    60721 ttttttatag ctgtattagc cactaagtat atttttaaag gtccaagcac tgcttctctt
    60781 ccagggttga gttggttaat agtttttgga tgttattcaa tttataataa aaaatataat
    60841 gatttagttg atgaatcatc tgaatttata ctatcaaagg ttaataaaat tgcaataaaa
    60901 ataatgatat attctatagt aataatatct attttctttg caacacctta tacaagtaat
    60961 ataaatatat caaacataga tacaggtata atcctcattg cagttttatt tatacagtct
    61021 ttatctaaat tagtgttgta tatatacttt gataaaaggg ggatatgtaa ctaagtggca
    61081 atattgatga aaacaaaaat taaagaatac agagaaaaac tccttatgac gcaaaatgaa
    61141 cttgctaaat tggttggggt aagacgtgag actattgtac acttagaaaa tgggaaatat
    61201 aatccttctt tgaagttagc tatggatatc gctaaagtat tcgatactac agtagaaaat
    61261 ttgtttgaat ttattgaaga agaatagtgg aaagtttata aacattta
//
LOCUS       DACTZW010000012        58524 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.012, whole genome shotgun sequence.
ACCESSION   DACTZW010000012 DACTZW010000000
VERSION     DACTZW010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 58524)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58524)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58524
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.012"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            410..511
                     /locus_tag="JAM15_04150"
     CDS             410..511
                     /locus_tag="JAM15_04150"
                     /inference="COORDINATES: protein motif:HMM:NF024363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3850 domain-containing protein"
                     /protein_id="HAT6797455.1"
                     /translation="MSFTGRYIKAKITYISDYQQKDNYVVFSFEKEF"
     gene            661..1233
                     /locus_tag="JAM15_04155"
     CDS             661..1233
                     /locus_tag="JAM15_04155"
                     /inference="COORDINATES: protein motif:HMM:NF025027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HAT6797456.1"
                     /translation="MNFWENIDDELLSKDYICGYCGCYIASQKGYEGFFRTGPDEQIR
                     IGIYLCPKCVNPTYFDKDNKQYPMAKAGNDVLNINDERIKGLYEEARNSFSVKAFTSV
                     ALCCRKLLMNVAVYLGAEENRKFIFYVDWLDRENYILPNSKKWVDQIRKIGNEATHEI
                     CIISKEDAEKTLFFTEMLLKMVYEFPAMVE"
     gene            1303..1986
                     /locus_tag="JAM15_04160"
     CDS             1303..1986
                     /locus_tag="JAM15_04160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAT6797457.1"
                     /translation="MQDVKEKVKQDYLKGMKQKEISAKYDISLNTLKSWIKRYNWASE
                     KKKGAPKNKRGAPIGNKNATGPPGNKNAEKFGFFSKYLPEETQDLINEIKNKDKFDIL
                     WEQITIQYAAIIRAQKIMYVKDKEEMIKELKKHESTENGEKIEYEFQFAWDRQASFLN
                     AQSRAMSELRSLIKQYDEMIHKDWNLATEEQKTRVEKLKCEVANLNKDDTDKEITVRV
                     MKASGENGK"
     gene            1976..3328
                     /locus_tag="JAM15_04165"
     CDS             1976..3328
                     /locus_tag="JAM15_04165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003378062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HAT6797458.1"
                     /translation="MESKFISNDHFYDFIFNWDYKFYFLVGGYGSSKSYHVATKLIIK
                     LLEEKRKALVVREVYDTMRDSCFSLLEEVAESMGLGDILSFKTSPMRVIFPNGSKIIF
                     KGMDNPAKLKSINGVSIIWLEECSEVKYTGFKELLGRLRHPSLSNHIICSTNPIGEDN
                     WTYKHFFRDEEKDRFVLDDTVLYKNRIVIKNNTYYHHSIADDNFFLPESYIEQLDEMK
                     EYDYDLYRIARKGRFGINGTKVLPQFEVMEHQEVINKISNIPQRYYKVGFDFGFEKSY
                     NALLRLAIDHENKYLYIYWEYYKNQTTDDVTVKDIKEFKDTQELIKADAAEPKTIKYF
                     RQQGFNISGAKKYAGSRLQNTKKVKRFKKIYCSSECKHTIKELKNLTYATDKNGNLIY
                     DEFNIDPHTFSAIWYALDGYEVSDIKELKYNNDIYNKGLGLKKNNIPNQYNKKGGAVF
                     "
     gene            3328..4851
                     /locus_tag="JAM15_04170"
     CDS             3328..4851
                     /locus_tag="JAM15_04170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011099331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAT6797459.1"
                     /translation="MSIKNILLNLDEKELKDRKHAERDFLFYLGECRNKTMGLLDDDF
                     LGQSWITFDNLDYAPSQIIDNKVKPLINKQTRFMFGKEPTIILKAYEKEDKETCEELR
                     QYIDSILNASKFWSNTLKAFKIATITKRVLLRLEAEPNQPIRLFYHSMDDFKYQVDSN
                     DITKLKSVIFVRFDASTIKEVTANQIWYRYTYYMKESSVNNQESCFLRVEKFKGDNLS
                     KPIEVKESDTKLSKIPCWIIVNEQSITNITGISDIEDLKPLQDTYNKRLSDFNDSLKF
                     LMFGQTVVVDATEETVNACKIAPNALMALKTLEEGSEKGKQAQAYRVESSFSNADPVD
                     SFFKRLEDSMYEKLAIPRPEQLQNIPSAKALKYLYTELIARCSEKWNDWEPAIRSMLR
                     LIVEACSKFNCYDDWNHDWDDLMFSIVLNKNYPIPEDEEDSKRLALEEVNNNVRSHRN
                     YIKEFGDDEDYEEAFNEVLEDNEKIQSVEQDQFRKDAEIEIDDIDEELNSKSNNSDE"
     gene            4864..6483
                     /locus_tag="JAM15_04175"
     CDS             4864..6483
                     /locus_tag="JAM15_04175"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797460.1"
                     /translation="MKDNTYTKKVLEARKKLLLLDKKIQLEILNVYKDASKIILNDIA
                     KNKELNLSTKYLKKLNKSIERYINELNQRLVPVAEKSVIEASNIAKELQMYYYQSIVP
                     NTAMNLACDAMCIKTTTGVVKKIVAGNFYKDKRSLDSRIWGYSNKNRKDIDRLIKANI
                     ARGANAKTLAKSLDNYVNPTKRTDAKTLEIGMNKSISYQAQRLARTSITHAFVETSVQ
                     NAINNPFCVGLQWNLSSQHYIRQVKWRGEDECDEYAEQNRFGLGEGVFPPEKYPIPHP
                     NCLCYPIQVIVPISEASKMMENWIGGGDNDTLDSWFDGIRHQNNSVPIIKKQRNKKNK
                     IATNSKDDRIKKNLTNSIKNKSKKAPKQVQKYINKYVQPSKILIDNSQKIPFIYYTKV
                     DLIGINPNIKEFKSYNKEAALLHEFAHRIDIKEIKSYNNIKFQKAIENSSIYVMKNIE
                     NLQSIYTNSNELYNNEFISDILGALSNNEFEDLLATHSEKYWSKNRNKEKEIFANLFT
                     LKYQNNKEINSFIKEHLNDLDKIFNELLGGI"
     gene            6485..6637
                     /locus_tag="JAM15_04180"
     CDS             6485..6637
                     /locus_tag="JAM15_04180"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797461.1"
                     /translation="MLEEMRKDKKLLELRRLYKEKYGKNAPGFNYDEYNSYAEYKEKL
                     KELIQK"
     gene            6705..7358
                     /locus_tag="JAM15_04185"
     CDS             6705..7358
                     /locus_tag="JAM15_04185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003494198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffold protein"
                     /protein_id="HAT6797462.1"
                     /translation="MLEYFKKIFGDEEGQKIYEKLSKDKENKLLLDNIKNSKYVEKTE
                     LENANKEIKEYKKQIGDRDKQLNDLQGKVKDNKELSDEIESLKNANKEIKENAEKEIE
                     VLKFNTALERAIESYNPKNAKALSALINKENINFVDGKIIGLDEQIKAYQQSDSYLFN
                     NEKNKGDDENVGTGGLEGGTTSLLDNDNEISSIGELLANSKVKSENIEAQKKFFGEE"
     gene            7370..7726
                     /locus_tag="JAM15_04190"
     CDS             7370..7726
                     /locus_tag="JAM15_04190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003378058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797463.1"
                     /translation="MSIEKSEIYMGENKTILKFAGNLFQNVNIKVKKTDVAVVDGKRI
                     LKAGTLISKDGKLVDGTTVTNDKSFGLVYRNIDFTHSNGNESIPVLIFGFVDEKNLPS
                     VIPEEAKQAMKMIMFL"
     gene            7750..8781
                     /locus_tag="JAM15_04195"
     CDS             7750..8781
                     /locus_tag="JAM15_04195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011099336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HAT6797464.1"
                     /translation="MDWKDFIDSKEIAKYIKKLPLEMLIGESLFPRKKQIGMDLKYIK
                     GAKKKPVVLKQSTFDVAVKIRALKAQIEVKSKRMPFFKESVLVNEEDRQQLLLASKAQ
                     NKELLLMIISQIYDNYLALVDGGDMQMERMRMQALADGVINIVSEDGDLVFDFEVPSN
                     HKEVLTGSATWDNPDADIIGDIQRWMRIMRDEGKPLPKRMVMTSKTFGYFAKNKAIKL
                     DIDKDGRVILTDEMIKNYLKNKVGLSVAIVSGTYKLEDESEESYFPDNKITFIPDGDL
                     GKTYYGTTPEEADKVYGSKLDCSVVRTGIAITTMRLIDPVTVQTKVSQLGMPSFERAD
                     ECFFATVAS"
     gene            8796..8996
                     /locus_tag="JAM15_04200"
     CDS             8796..8996
                     /locus_tag="JAM15_04200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003378055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797465.1"
                     /translation="MAKKKDNLMQVKALVYLKYDNDCYKIDDIFEIRKADQKLMEENG
                     YIEVLGEVEEKNNNEFLNKDGE"
     gene            8999..9316
                     /locus_tag="JAM15_04205"
     CDS             8999..9316
                     /locus_tag="JAM15_04205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002581887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797466.1"
                     /translation="MSITNLDKLKLNLQEEEYPYFTDEQLEMLLESNENNVLKASWRG
                     CLLKGATDDCIKIGPIETKSSNSSYWLSLADIYKTDYLEEKSKNETTNTGYKTSMARV
                     DGQ"
     gene            9313..9696
                     /locus_tag="JAM15_04210"
     CDS             9313..9696
                     /locus_tag="JAM15_04210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019278971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797467.1"
                     /translation="MRKLRADKIIKTINRGIALNPQTITIEQEVKNIVDGAIDITNEV
                     KKLTVVIYPEKTNDTVINSETIGTAYKNKNFGMVADKEADLKLNTESDITFKCIEGTM
                     KLNYVNPIVVEEKICGYICGLEKID"
     gene            9715..10119
                     /locus_tag="JAM15_04215"
     CDS             9715..10119
                     /locus_tag="JAM15_04215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014521148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797468.1"
                     /translation="MFTKAINEIDRKKATMPILCMNIAFMLEGEAKNSAKWTDRTGNA
                     RQGITGTSLGGGNQYIVRLGHGVDYGTVLEEGSAPHVIKPRNAKALFWNGASHPVKQV
                     QHPGTKGTHSLESTVSRNMPKIGKLVEGHWSK"
     gene            10121..10945
                     /locus_tag="JAM15_04220"
     CDS             10121..10945
                     /locus_tag="JAM15_04220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797469.1"
                     /translation="MRAGIRNTLIENISKLKDCYEPTVPNKKTIKPYAVIVQGEDSDS
                     EGEVIGFRRNINIWLYEKRTTFNKLDELTKEVIETLDFKTITDDTTNEVFTCIYEGAV
                     GQDVIDEEWEAIIRCLRFSVIALDDKEDITSDRWVEALSKYTKDLLEIESYKDNWKKN
                     FIAPCALWRTTHIENKRINYHLIEITKTMKCHVVSKNKDEIVKLLEELETKLIIDKRV
                     RLREDKNMYLTLVSVVEDRESDMFSNGQLTVVFKMIGKIKREGPIMNKIYSNGNLK"
     gene            10958..11161
                     /locus_tag="JAM15_04225"
     CDS             10958..11161
                     /locus_tag="JAM15_04225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797470.1"
                     /translation="MAEAINKKTNISKQEEKYSKEDFLKNSEALGYKKEVVAGALFNC
                     KKDELTKSEFEKVIKDFLEREVK"
     gene            11163..12584
                     /locus_tag="JAM15_04230"
     CDS             11163..12584
                     /locus_tag="JAM15_04230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath protein"
                     /protein_id="HAT6797471.1"
                     /translation="MATGTWNEKEKKDIPGFYNRFKTQAEKSTNTGLKGRLAMPIRAN
                     WGDVGKVITIKNDLRQLKTLFGDDMNYSAYKLGKLALLGNVKELLLYRLVDGNQKKGT
                     LTLKDTTENTAKDVIKLETKYPTSRNFNVTIKSNLVDSDKKDFIFFEGTKQLFSSSVK
                     GTIDEIVLEINSNLDNEYVIATKVADSDTTLANLVNVALEGGNDGCTSITNESYLKAL
                     EEFERYSFDSFVLDGVAEEALQETTKTWVAKNKELGKDILLFLGGKKEDNIKQINDKS
                     KSFNDENIANVGSSAYYENVKYTPSEVAVYIGALAVSKGITGSICNAKTIFEEVEPRL
                     SQSEVKECLKSGTLILDFDDGDVIIVDDVNTFKKYVDDKNEAMGYISNIMFINTINKD
                     TSLKRKEFVGKIFNDATGQTTVICALKKYFEELMSQGVISEFNVDIDTELQATAKADE
                     FYWKWDAVKVDVMKKIYGTGYLG"
     gene            12600..13022
                     /locus_tag="JAM15_04235"
     CDS             12600..13022
                     /locus_tag="JAM15_04235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797472.1"
                     /translation="MGKYDENIIDAANVVDGSNARIIIDGEEEGYGTEFTAEVENDKK
                     TFRVIGCKWELNKASTQKGTFSFTVLKTTSKWIKKGFNKFEIITEIENPGLVGYERIR
                     YKNCMVDKIQLASIKSDENIEIQIDGTFEGYELLDEIA"
     gene            13099..13572
                     /locus_tag="JAM15_04240"
     CDS             13099..13572
                     /locus_tag="JAM15_04240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797473.1"
                     /translation="MANLDKEFLNEVIEEERELTKDEIAKQQEDNIIMKLTEDAILPE
                     KTIFVKRLDIPLTLRALTEKEISALQKKYTKVTKVRGRRESKLMEDEFNIALIEKATI
                     VPNFSDARLLNSMNVSSGVEFIRRKFLAGEIALISDEVLELSGFYEELSDDDIKN"
     gene            13753..14964
                     /locus_tag="JAM15_04245"
                     /pseudo
     CDS             13753..14964
                     /locus_tag="JAM15_04245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994354.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
     gene            15227..18304
                     /locus_tag="JAM15_04250"
                     /pseudo
     CDS             15227..18304
                     /locus_tag="JAM15_04250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994354.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
     gene            18384..19241
                     /locus_tag="JAM15_04255"
     CDS             18384..19241
                     /locus_tag="JAM15_04255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797474.1"
                     /translation="MWDKFKSLNVFLKILIVIIAIGMLPATLFFLSIVLFVTLFKKKK
                     KIACIMSLILVALTFNFANFWYSMDTTVTASNTKTEETKNTDKKKLEEKKTKEEADKK
                     KEQEEQKKQEELKKAEEQKKQEEKKVQTEQQKKDEEAKKIADEKKKQEDNEKKAQAEQ
                     TKKNELVKKLETYENIYLMIPASIEEKSASNNALELQKTFSTGRDVASKCWQELGDLK
                     DKYSTESNEYKAIQNLQLAFFVVKDACKNGIKYLDKNEYKYYEKYEKNCNEAGAWYSD
                     FVTLKEKIK"
     gene            19321..19992
                     /locus_tag="JAM15_04260"
     CDS             19321..19992
                     /locus_tag="JAM15_04260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAT6797475.1"
                     /translation="MVIDIYLKNEKEKIDLHFPVNPLDSLSIKKEKRFETVDIVNLGE
                     FDIKKEGEKIREISFKTFLPNLYDASYCRYSELKNPIEIVAMLEKWVDQAEPLRLIIT
                     GFGYNGLVTISSFSNTQTAGREEDRDIEITFRTYRELKIETLKKETKSNTKTDLKDNR
                     PNTQTKSKIYTVTSKDTLWSIAKKFLGKGSRWKEIYNIPENKKVIGKNPNVIKKGQKL
                     VIPSK"
     gene            19989..20951
                     /locus_tag="JAM15_04265"
     CDS             19989..20951
                     /locus_tag="JAM15_04265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdQ"
                     /protein_id="HAT6797476.1"
                     /translation="MKIILNGKYDIANFNEGITLSEAIDGVAYKMDVSLVEPKQLQDI
                     GIKKGDKIVLIDIAYESKKEETIFDGVIWETRRSEKSKKLTLSCRERTVYMEESEEQY
                     SFKENTATQRIEYYCKQWNIPYYNLANTGKKLAKVIHKTNILDMIKKDLKETASKGGD
                     LFRVRMDNKLKLFKLGTNAIVYKLDSILEDANFTSGFNDAVTSVKVLGKSKDENTKAP
                     IIGTYKKDSDKYGTLQKIKQDEKITNAKEAKKAAEAMFNSGEETISVDCVVDINRIRA
                     GDKVSLKGREYYVIDVTHTLDSTPKMKLNIGTLDYIRRKFYNND"
     gene            20944..21309
                     /locus_tag="JAM15_04270"
     CDS             20944..21309
                     /locus_tag="JAM15_04270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797477.1"
                     /translation="MTDARFNGVARILKEKMNKSVNDGVFGMGCSLAEITTNGLKVNG
                     YKDEIQDYLVLENLTLKEDYFAFSDEALSGEYRHKHKIETPQELNPLDIGDNVLVAIM
                     GAEFVVIGRVVNAKPISAE"
     gene            21284..21742
                     /locus_tag="JAM15_04275"
     CDS             21284..21742
                     /locus_tag="JAM15_04275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HAT6797478.1"
                     /translation="MPNLFPQNETFETVELKNNNKNELDLKESFLFDFIKGEFVKNAD
                     GTLKRCNKVEAYKQWCQKAILTPRYKRSAYSSVYGSEIKDLIASNLSQSAKELEISRL
                     IKETILVHPYTKEVSNFIFNWLENSSLVNYEFDVLTIDDENIVIDGNIKR"
     gene            21751..22887
                     /locus_tag="JAM15_04280"
     CDS             21751..22887
                     /locus_tag="JAM15_04280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HAT6797479.1"
                     /translation="MERELPIPVFLTEDEEAIHERMLSNFQDVSILEGDFVYDATRPT
                     AEQIAELKQLGLQNNLKIAFPQTSYGTYLEWLGECKGVFKNQPTKSVGMVTFTGVQGT
                     IITKGTIVTTVATDEKQSIEFELLETKTIGESETVDIKAECRETGTIGNVSQNTVTVL
                     LGSINGIKSVTNKESFKGGTDIEDEEHFRERVLVAEQEDKLSGANSDYIRWAKEVDGV
                     GYAYVVAEWNGAGTVKVLILDKNRKAATQELIDKVQEYIYPLNVSEGENRDGKAPIGA
                     IVTIATPRTLLINVKASFVFSNGFSQETVLNILKNKIDKYLDKIDIGGTVSYNAIYSL
                     TGSMMLADEGIQDFSNLTINDGTTNIILNDQVVGIGEIVNEVIA"
     gene            22884..23654
                     /locus_tag="JAM15_04285"
     CDS             22884..23654
                     /locus_tag="JAM15_04285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmfQ family protein"
                     /protein_id="HAT6797480.1"
                     /translation="MITSKKGREMLLTLSPIYEQSLIMNSIYEAIGSEFDNLELLNKE
                     IELQLFPQTATWGLNFWENRVGLSTNLDEDIETRRRKVIAKLQMKYIVNPSRLATIIK
                     SYTGTDVYIKEDIAPYTFKVTANVDDVINYEDFKYITNKTKPSHLHWMPSFALKFTDI
                     EKFEVKMVNRMFIDFRGNISNFLDGMWLLNGSKNLSAYILYHEPISLNMKNKLFIKES
                     EVFTNIKIIIKKNLYYLNGIEVLNGNKLLNAELREEVL"
     gene            23657..24037
                     /locus_tag="JAM15_04290"
     CDS             23657..24037
                     /locus_tag="JAM15_04290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797481.1"
                     /translation="MANAVTTDIARQKMCKARAGDITLPTIVSMVFGDGGIGNDGTPI
                     APLSSDTALKSEVFRKDIENYIYPVPTTCRYSTTLLKNEAEGKNISEIGLIDSDGDLI
                     AIKTFGNKYKDSDMEMVFQIDDEF"
     gene            24049..24663
                     /locus_tag="JAM15_04295"
     CDS             24049..24663
                     /locus_tag="JAM15_04295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797482.1"
                     /translation="MPNKLNFNNEIEEYLITTPAHANEFNKRQNSLLENDKYLNNKID
                     ITKTELNTRIDTENEKQNIKIDNIIAGGVNVSHTHIIEVADWVLNSETNMYEVTIENP
                     LLTERILISMYNENGDTLVPDATVKDNNIIVRSTENNRTFVYLINGNAQTSLINVNID
                     DNRVSEMTAYSSKKIEDRLVNIEEKLNGNLSTIATSVNELITYC"
     gene            24679..26298
                     /locus_tag="JAM15_04300"
     CDS             24679..26298
                     /locus_tag="JAM15_04300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797483.1"
                     /translation="MATEWNFNFKAEPQPITLKAGRYKLECWGACGGKKGVTAGNGGL
                     GGYAKGELTLKKETILNVYVGEQGRDGSNAWTIFNGGGFGGVSTGGGATDIRLIAGDW
                     GSQIGLLSRIIVAGGGGGHDSDTSTGNYSSAGGGTKGNNGVSTLSYHTPGATQYDGGR
                     GADIHCDGSFCLGGGTITYLQYCKCGGGGGWFGGAGSKVSSSAGGGSGYVLTKDSYKP
                     AGYTPTSEYYMINPNLATGNNTTKGHGYAKITLLQSLPFLNVISYNSTTATFKADHTD
                     PALLTKIECFIDDTLKETITEDLTTEKTINYTLEDNALHTLKIVVTDSANATVEKVLS
                     ISKNIMPLPENVNLNDISTKLVEVSTGFKVGKTSIINTLALKNIEASLNNTLVELSEK
                     IKTSFDSSDASVQDLMNQLTQANNTISQLNTQINGLNSKYKYAYSTDVTLHWYVDCGF
                     RPDFVIYDCQTTRGRLFVILTPSIYACFDTSNRRWSIISSDYENSYAYSKNNINSYYG
                     TEIRNTGFNCSAMPGDSLNDKYYFYYAIKCL"
     gene            26311..26610
                     /locus_tag="JAM15_04305"
     CDS             26311..26610
                     /locus_tag="JAM15_04305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797484.1"
                     /translation="MKNIGRIVFYDNDTGDILMFYGEKTVSDSININIPKIDSIELPY
                     GSIDYTRNRLIGINVETKEPILEEIKIELTEEEKKIQELENQLLIAENEKVGGLL"
     gene            26610..26792
                     /locus_tag="JAM15_04310"
     CDS             26610..26792
                     /locus_tag="JAM15_04310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797485.1"
                     /translation="MNINNVVVRILAERILNKGLNPLKNRVFELDDVTNTEYRIAVEN
                     YIIEHSGVVEGTQPTK"
     gene            26834..27064
                     /locus_tag="JAM15_04315"
     CDS             26834..27064
                     /locus_tag="JAM15_04315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797486.1"
                     /translation="MNEEVIKEKIKRNEIRINRHSDEIDELKIANIESKAELKALCEN
                     LNSLTSMLKWLIGTMITTLVGFFIFAIQKGIF"
     gene            27084..27341
                     /locus_tag="JAM15_04320"
     CDS             27084..27341
                     /locus_tag="JAM15_04320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin"
                     /protein_id="HAT6797487.1"
                     /translation="MDNLISFIPEQLLILVAALSIIGKGCKKYKQLDNKYIPIILLVL
                     GIGFSIWMLGFSPNAVLQGIICWGISIGINQTYKQLKEENK"
     gene            27341..28150
                     /locus_tag="JAM15_04325"
     CDS             27341..28150
                     /locus_tag="JAM15_04325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAT6797488.1"
                     /translation="MKICITVGHSILKSGACTSADGVVNEYQYNKSLAPILADTFRKE
                     GHKVDVIICPEKQFKTKSEEKSYKIPRVNSGGYDLLIELHLNASDGQGKGSEVLYYSN
                     KGLEYATRICNKLGTVFKNRGAKLDKRLYILNSSKPTAVLIESFFCDNKEDYDKAKKL
                     GHEGIAKLIVEGVLNKNINNEGVKQMYKHTIIYDGEVDKIPATVVGWGYNDGKILICD
                     IKDYVPGQTQNLYIVGGGACNKISSITKERYTVIKGNDRFDTLYKALDFIK"
     gene            28510..29025
                     /locus_tag="JAM15_04330"
     CDS             28510..29025
                     /locus_tag="JAM15_04330"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797489.1"
                     /translation="MFKKAKRIITLAAMISMVGGSILIGHADEENTYSPETGELPYQG
                     LELNVSPTTRSAEPRTYTYKYSGEFKNYTQSGAFVSTGRQKIIDGYQRTKTATASTGV
                     QYQIITKQGSKLKYVTRTGVYNGNLSIDLSHNNTVGSDRKLRLANYYNLSFDDPNAPV
                     QSASGQFNYLY"
     gene            29316..30605
                     /locus_tag="JAM15_04335"
     CDS             29316..30605
                     /locus_tag="JAM15_04335"
                     /inference="COORDINATES: protein motif:HMM:NF013697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAT6797490.1"
                     /translation="MNMKKLTILLGALLICSVLIFSQNRESINGLVLYKSEVSSYDTL
                     KNYLKKELNINLQVDYVIDDNEISKEHDFWEYPRVQLINKLNNNNIDLLLDIPNEYLR
                     DSMKDEKLLKLDNYIDTHNIYPAIIDKSKEIGNGNMYFISPYFSSNFIMINENLFEKL
                     NIPIPNEIKSWQDVLKLLKDIKSSIKDNNVSDIYPLSLGMNGTESFFQDFEVLTTPFN
                     LSVKSEGTIYDDDKWMDVFAFFMNLYKDYGIHKTINTADMFIDDKIAMKFVQGIEIMN
                     YKESMGKYKVFEIPSYKEFKDKIYLNTTDISIPANAPNKENALKILNHFLSKEFANKG
                     VDGRLFGMYPFVSYVDKEILDKCRDFYNLKNPNVLYPDKPGYANKNEFILFNDYVNYQ
                     QSQREVIPNIINGKISIEDGFKEIKDRYSQTIKNISK"
     gene            complement(30704..30904)
                     /locus_tag="JAM15_04340"
     CDS             complement(30704..30904)
                     /locus_tag="JAM15_04340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797491.1"
                     /translation="MCFKTYILKRVVNNKQLEITRSFDLDNLICTATEILKDNEIDLI
                     IIDEKNKVVWRNEKSTPRHENA"
     gene            complement(30923..31336)
                     /locus_tag="JAM15_04345"
     CDS             complement(30923..31336)
                     /locus_tag="JAM15_04345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797492.1"
                     /translation="MKVKNRRGFIVGIIASMLCCASIVIYCILKEQRFLISSFLLITI
                     AIFNFYNAFSRKGIVEELHDNADERDLYLTMKTSHILVKIMNYTLCTFTFLFIIAYSA
                     WKNQSLLVIAITLCIIEIFLFVAYLLINIFLEKKE"
     gene            complement(31320..31553)
                     /locus_tag="JAM15_04350"
     CDS             complement(31320..31553)
                     /locus_tag="JAM15_04350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6797493.1"
                     /translation="MKTKVRELRTNMGLTQQQLADLVHVSNRTIISIEKEQYSPSLML
                     AYRIAQVFDTTVEELCCLKENKEMEDKKHESKE"
     gene            31771..32154
                     /locus_tag="JAM15_04355"
     CDS             31771..32154
                     /locus_tag="JAM15_04355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HAT6797494.1"
                     /translation="MKISKLPDAELKIMKYIWNTGYKTVISKDVADEIEKTYGWKHTT
                     TITLLARLTKKGFLISQRIGKHVHYTVLVKEREYLKLEGKRIFGGLHNNPLSELISKL
                     HDGEEITEEKIIEIGNWIKSWKDED"
     gene            32516..33724
                     /locus_tag="JAM15_04360"
     CDS             32516..33724
                     /locus_tag="JAM15_04360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HAT6797495.1"
                     /translation="MKKKIGLVPKLIIGIIVGILIGSYAPEIIVQILVTVSTLFSAFL
                     KFVIPFIIIGFVTAGIADLATGAGKLLGITTGIAYGSTLIAGLLSFAVSTLIFPNFID
                     ASVASQIGDPEAGMLAPIFTIPLEPMVDVTAAIVFAFVMGLGISALRNHGKGETLFNF
                     FQEFQGIVTKTLSTVIIPLLPLYIAGTFANITIAGEVWTILGVFWKVYLVVIPLHFVY
                     MACQFTAAGVFSGKNPVRMLKNQVPGYLTAIGTQSSAATIPVNVGCAEKNGVSKQIRE
                     FVVPLCATIHLSGSMISITGFTTAVLMMNGMPHGIGVLFPYIAMLGIAMVAAPGAPGG
                     AIMSALPFLPMVGIPSDGGLVSLMIALYLTQDSFGTACNVSGDNAIAVVVDKINDGIS
                     KKGNKEEQSA"
     gene            complement(33811..34887)
                     /locus_tag="JAM15_04365"
     CDS             complement(33811..34887)
                     /locus_tag="JAM15_04365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003415975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HAT6797496.1"
                     /translation="MSTNHGANLYSLSSKYGFSKEEFMDFSSNINPFGTSSLAKQYIV
                     NNIDMVSMYPDPDYIDLKTSISNYCKCSIDNIVLGSGATELISSFIHTINPKQALLLS
                     PAYSEYEKELSKINCSIEKYFAKEEDNFHINLENLIKTINAKDYDLVVICNPSNPTGF
                     AFTKVEVREILKNTDSFLMIDETYVEFTDTDTYSCTQLVDDYSNLFVIRGTSKFFSTP
                     GIRLGYGLISNTNVKNEINKNLDLWNINIIASKMGEIMFSDLDFISNTISLMNTERDY
                     LLKELKNIKSLDIYNTKGNFILCKIKTKELTAKSLREQLLPQKIIIRDCCSFEGLDEY
                     FFRVCILKPNENKLLISSLKAIFK"
     gene            35116..35643
                     /gene="hpt"
                     /locus_tag="JAM15_04370"
     CDS             35116..35643
                     /gene="hpt"
                     /locus_tag="JAM15_04370"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HAT6797497.1"
                     /translation="MYKVTGKMLTEEQIKEKVYELGKKIEEDFKGEDLLVVGILKGAS
                     VFVSDLIRCIDLDVNIDFMSVTSYGNSTESSGTVKILKDLDVDIEGKNVLIVEDIIDS
                     GLTLSNLVAALKTRNPKSLKLCTLLDKPQRRKANIPVDYVGFVIEDKFIVGYGIDYAE
                     KYRNLPYIGIVEDVE"
     gene            35732..36664
                     /locus_tag="JAM15_04375"
     CDS             35732..36664
                     /locus_tag="JAM15_04375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HAT6797498.1"
                     /translation="MDIQLNILLFFQNLRNPILNFIFLVFTISTEAPLLILITTIIYW
                     CINKKCGQKILFAIIGNFVVNLGIKEFVKAPRPIGIKGLESLRVSTAGGYSFPSAHTQ
                     TATTFWVSIMTIFKKRYLHLIGAVMVLGVGLSRLYLAVHWPIDVIAGWILGIFFTVIF
                     VKIFDYIDDNKNYILLVVLLIPFIIVAIFLNSPEYFEKFGIIVGFVFGYMVEDRFVKF
                     NTDNNNKKINFSNKNKGSKNIIFSRICRFLVGIVTIGMLYIGIKLFISMLIVTLNISD
                     STMSIIFMNFIKNTVVVFYGIAGAPALFKLLKLN"
     gene            36726..37952
                     /locus_tag="JAM15_04380"
     CDS             36726..37952
                     /locus_tag="JAM15_04380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAT6797499.1"
                     /translation="MKKVVIIGGGPAGMIAASTACEKGYDVTLIEKNHKLGKKLAITG
                     KGRCNITNACEIEELIENVPTNGKFLYSAFYTFTNDDVISMFNNLGVKTKTERGKRVF
                     PESDKAFDIVNALERQLKSKKVNILLNSKVEKIISKNNKIEKVILNDKKEIKCDSVVV
                     ATGGLSYPLTGSTGDGYKFAISQGHTIIDTKPSLIGIEVKESFTKDLEKLSLRNVEIR
                     VFNSKQKKVYSDFGELEFTRFGLDGPIIKSASCRMKDTRKENYTILLDLKPALDEKKL
                     DKRVQKDFQKYTNKKFEKALDDLLPKKLIPVIINLSEINANTVVHQISREQRKNLVHL
                     LKNLKFTVKRYRPIEEAIITSGGVKVNEINSSTMESKLVEGLFFAGEVIDIDAYTGGF
                     NLQIAFSTGYLAGFNC"
     gene            38036..38257
                     /locus_tag="JAM15_04385"
     CDS             38036..38257
                     /locus_tag="JAM15_04385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HAT6797500.1"
                     /translation="MASNNNNNRTVVPGAKEALNQMKLEIANELGMSNYQQVDKGNLT
                     ARENGYVGGYMTKKLVEMAEQQMAGKSNR"
     gene            complement(38709..39170)
                     /locus_tag="JAM15_04390"
     CDS             complement(38709..39170)
                     /locus_tag="JAM15_04390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797501.1"
                     /translation="MQIEQLDLETRNKIYCYTKKILRKYQKGITSGKLTADKFADNIL
                     SQHFISSILNEKIVNETNFKISYRNYIETLINIQNENLSNLRKKSTKTAKCFNISQIT
                     QLKNLLSNTGYNLLIPYKYLTARDIEGIVTLINTGSIELGNERIYNYISKA"
     gene            39359..39820
                     /locus_tag="JAM15_04395"
     CDS             39359..39820
                     /locus_tag="JAM15_04395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797502.1"
                     /translation="MLNGIIKLFYSEIVKTKINNLDSSGYSLRDECKEIRNITLKIDS
                     VFFKLLKLAFGSILLMIAFNLNMILGIGVFLIGVVYILYKRNMEEQVKEHINNVKNNI
                     DISKITFMDEKGRTGLNALITLLLIGLLTGFNWILVASFVVVFVFTIKNVC"
     gene            39863..41626
                     /locus_tag="JAM15_04400"
     CDS             39863..41626
                     /locus_tag="JAM15_04400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="HAT6797503.1"
                     /translation="MTNGSYKMKNLVEISAMVTESTDFFNIKDDIIEKMLEVVHPTKA
                     CVNLFYKNDSKYAYLVCSQTLEYVPQIFPINSLKGAKIDFDTYPEYIHEAVNEKKIIY
                     VENVFEDSRAEGERDLAKAEGYIGRIVFPFIINNVVVGFMTCFLKEDDYITEQDIDFI
                     SSVASLLSLSIEITNKNNNVQILIDKLRGSISAINEATKKLYLNKSIDGFLENLSKQA
                     CNITNSKEALIIINSHHNKDTIVSCYNVEQKKKTNLYPMIDMFLKKESLGGYLNNLKP
                     CSKKGINLESYIYYKLQDKNETIGCIVCANSKNYTSDDLNILSILSKQVSVGMQLYEH
                     NEKEVKHKVLENELNILNKQQQLIMDKGKMDCNDEKELYFYHKPSRVVGGDFYYATKV
                     DDEHIVYIVADVMGHGMVSNYVVAMIKGAFKVLCNQYNTPREIMTNLNRMLYDEFDKM
                     GVFTTCLIGIIDTKENMITVSNAGHYSPVVVKKDGTIENNLNCKKGIPIGIMEDATYE
                     NNTLSMEDYAMVCMYTDGILEIKNSSKEEYGINRLENFLKENFRLNQQLIVENLKLDL
                     KNFSSKDNYDDDILIVMLKDR"
     gene            41634..42242
                     /locus_tag="JAM15_04405"
     CDS             41634..42242
                     /locus_tag="JAM15_04405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HAT6797504.1"
                     /translation="MDSNDKKGLKSPEIIIINGSPRINKNCSFIANKVKAMLEECGLS
                     CKIFNIYNMDIEYCTACGFCEKTGYCKFNDDMKPLYKMFDDSKGTIVISPVHFDSISA
                     KLKTVVDRTQAIYASKYVLNKPSIDRNKKRIGMYIAVGGSKSYDSQFKGGQIVMDFFF
                     KSINTKLLHNIYLNNTDDVSYIDNQEFKDIIYKNLKIYIDSI"
     gene            42314..42883
                     /locus_tag="JAM15_04410"
     CDS             42314..42883
                     /locus_tag="JAM15_04410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HAT6797505.1"
                     /translation="MKLPIALSNKHVHLSQADIDVLFGAGHELTKFKPLSQPGQYACE
                     EKVDLVGPKGTLKGVRVLGPARAHTQVEISLADGFPLGVKAPIKESGDIAGTPGVKLV
                     GPAGEVEMKEGVIVASRHIHMSNEDAAKFGVTDKQIVKVKTSGPRALVFENVLVRASD
                     SFNLEMHVDMEEGNAAGVKNGDLVELIVD"
     gene            43401..46940
                     /gene="nifJ"
                     /locus_tag="JAM15_04415"
     CDS             43401..46940
                     /gene="nifJ"
                     /locus_tag="JAM15_04415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HAT6797506.1"
                     /translation="MAKFMKTLDGNTAAAHVAYAFTDVAAIYPITPSSTMAEVVDEWA
                     SQGRKNIFGQTVNVVEMQSEAGASGTFHGSLQGGALTSTFTASQGLLLMIPNMYKVAG
                     ELLPGVFHVSARALASQALSIFGDHQDVMAARQTGCVLLASGSVQEVADIAPVAHLAA
                     IEGRLPFIHFFDGFRTSHEIQKVELLENEDYASLLNFEAVQAFRDNALSPNHPVARGT
                     AQNPDIYFQTREASNKYYQNIVGIVEKYMEKMSNLTGRKHSLFDYYGAEDAKYVLIAM
                     GSVTETIEETIDYLNAKGEKYGLVKVHLYRPFSMKHFLDAMPSTVERICVLDRTKEPG
                     STGEPLYLDVRDVFYGKENAPMIIGGRYGLGSKDTTPSDIKTVFDNLVSEQPKNGFTV
                     GIVDDVTNTSLTPSEPIKIASKGTIRCKFWGLGSDGTVGANKQAIKIIGDHTEKYAQA
                     YFDYDSKKSGGITMSHLRFGDTPIRATYLIDEADYIACHKQSYVYQYDLLKGLKKGGT
                     FVLNTIWDQAGLEEHLPAHMKQYIAKNDIKFYTVNAVKLGQEIGLGNRINMIMQSAFF
                     KLAEIIPEEDAVKYLKDSIVKAYGKKGEKIVNMNYAAVDAGINALVKVEVPASWENAV
                     DADKGEVKEPEFIKNILRPMTAQEGNNLPVSTFNGIEDGTFPCGTAAYEKRGIAVDVP
                     EWIIDNCIQCNQCSFICPHACIRPVLVTEEELANAPEGFEAKKALGKGLEGLKYRIQV
                     SPLDCTGCGNCADICPAKEKALVMKPIDTQLDTELDNWAFAVNPDEVAPKVDVMPANT
                     VKGSQFRQPLMEFSGACAGCGETAYIKVVTQLYGDRMMIANATGCSSIWGASAPSIPY
                     TCNHEGKGPSWANSLFEDNAEYGFGMYTAVKQIRNKIVDAMTELVSMDICEDAKAVFT
                     EWLDSRNDGEASKVASAKVVELLEKPACDCTDEKAKELVKAIKDRKDYLVKRSQWILG
                     GDGWAYDIGYGGLDHVLASGEDVNVLVFDTEVYSNTGGQASKATPAAAMAKFAASGKK
                     SRKKDLGMMAMTYGNVYVAQVAMGADKNQFIKAVLEAEKHDGPSLIIAYAPCINHGLK
                     EGMGRTVANEAQAVACGYWHLYRFNPEVKAEGKNPFTLDSKEPTASFKDFILAQVRYS
                     AIAKQFPEEADGLFAKAEADAKERYEGYKKLAE"
     gene            complement(47334..48257)
                     /locus_tag="JAM15_04420"
     CDS             complement(47334..48257)
                     /locus_tag="JAM15_04420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein"
                     /protein_id="HAT6797507.1"
                     /translation="MRRNIPTKLKTILALGVLTLATASSAVTASASSLENNVNISNKS
                     LVYSNTKYKFSAKPNCSVKPELKPDKDNSCKDKNHNDKNCNNTNKPEDNNNSDSTNKP
                     DNNKPESNKPEDNNNSGSTNKPDNNKPESNKPEDNNNSGSTDKPDNNKPESNKPEDNN
                     NSDSTNKPDDNNNSGSTSENFSAYQKEVVDLVNIERAKAGLNPLTLDSSISNVATKKS
                     QDMIDNNYFSHNSPTYGSPFDMLKKFGISYKTAGENIAMGQKTPKEVVNAWMNSEGHR
                     KNIMNPNFSKIGVGVAQKSGGSIYWTQIFVG"
     gene            complement(48757..50091)
                     /locus_tag="JAM15_04425"
     CDS             complement(48757..50091)
                     /locus_tag="JAM15_04425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HAT6797508.1"
                     /translation="MSIIAPIGIIIGIIAIIYFSVKEIHITIAAPIATLIVVLLNKMD
                     VVTSMLGADKNNYMGALGNYIMSYFAIFLLGSILAKFMEESGATVSIADFILNKFGSN
                     HPYRVLVAIFIVSFILTYGGISLFVVMFAVIPLARTLFKKLDISWNLIQIPLWLGIAT
                     ITMTIIPGTPAIQNVIPIQYLNTSLTAATIPSIVGSIGCATFGLVYMKYALNKSIRKG
                     ETYATYTSELEEESLDRELPGFFASIFPLLALVIIAITGSTFGSEFMKKNVIYIALIV
                     AILLSAFLFHKFLSSKIQTLSIGASGSIGPIFATSSAVAFGAVIMAAPGFDVFSKLIM
                     SIPGSPLISLTVLTSTMSAITGSSSGALGIVMPNFADYYLSTGLNPELIHRVATIASN
                     ILTIVPQSGVFLTFLSLSKLTHKTGFKETFIVVAVGSLIAEIIVITLGLLMY"
     gene            complement(50153..50935)
                     /locus_tag="JAM15_04430"
     CDS             complement(50153..50935)
                     /locus_tag="JAM15_04430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HAT6797509.1"
                     /translation="MKMVKDKVVFVTGAASGIGKQIAESFLKNGAKVMFSDINQEALN
                     NTITELQKKGYDCMSVKCDVTKEEEINHAIDKTVEKYGRLDILINNAGLQHVSMIEDF
                     PTDKFEFMIKIMLTAPFIATKKAFPIMKKQGFGRIINMASINGVIGFAGKAAYNSAKH
                     GLIGLTKVAALEAADSGITVNALCPGYVDTPLVRGQFNDLSKTRNIPLENVLEEVLYP
                     LVPQKRLLDVQEIADYAMFLASDNAKGITGQACLLDGGYTAQ"
     gene            complement(51034..51699)
                     /locus_tag="JAM15_04435"
     CDS             complement(51034..51699)
                     /locus_tag="JAM15_04435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HAT6797510.1"
                     /translation="MDKLEMQEYIANRVSKELKDGAVVNLGIGLPTKVANYIPDNVNV
                     ILQSENGFLGLGSAEDGNSSDETIVNAGGQPVTILPGGCFFDSATSFGIIRGGHVDIT
                     VLGALQVDKYGNIANYMIPGKMVPGMGGAMDLVTGAKKVIVAMEHTSKGSAKILNNCT
                     LPLTATNAVDLIVTEMGVMEVTSDGILLKEINPTFTLDDVISATEAPLILSDSLNGKI
                     SVV"
     gene            complement(51699..52355)
                     /locus_tag="JAM15_04440"
     CDS             complement(51699..52355)
                     /locus_tag="JAM15_04440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HAT6797511.1"
                     /translation="MNKIVSIDEALSHVKDGDTIMVGGFMANGSPENLIDYLCSKNIK
                     DLTLICNDTGFIDKGVGKMVVNKQFKKIIASHVGLNKETGRQMNNNETDVELVPQGTL
                     AEQIRAAGYGLGGILTPTGIGTLVEEGKQKIVVDSKEYLLEKPIYADVALLFASKVDK
                     VGNLVYKGSMNNFNNLMASAAEITIVEADEIVEIGDIDPNEVNTPGIFVNYIVEGGNL
                     "
     gene            complement(52364..53542)
                     /locus_tag="JAM15_04445"
     CDS             complement(52364..53542)
                     /locus_tag="JAM15_04445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013711786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HAT6797512.1"
                     /translation="MKDVVIVSAVRTPIGSFGGVFKNTSAVQLGTIAVKEAISRVGLN
                     LSEIDEVIIGNVLQTGLGQNVARQIAINSGIPNSVPSYTVNKLCGSGLKSVQLAAQSI
                     TSGENDVVIAGGTENMSQAPYIVPTARFGSKMGDITMVDSMLTDGLIDAFNQYHMGIT
                     AENIATKFEFTREMQDKLALESQNKAENAIKNNRFKEEIVPVDVLIRRGKIETIDKDE
                     YPKLGMTFEGLAKLKPAFKKDGTVTAGNASGINDGAAMLILMSQQKADELGIRPLAKI
                     KSYASAGVEPEIMGTGPIPATRKALKKAGLSINDIDLIEANEAFAAQALAVKNELQID
                     SSKLNVNGGAIALGHPIGASGARILVTLIYEMQKRKVETGLVTLCIGGGQGISMVVSR
                     "
     gene            53897..54799
                     /locus_tag="JAM15_04450"
     CDS             53897..54799
                     /locus_tag="JAM15_04450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAT6797513.1"
                     /translation="MDIKQLKYFVEIVKSGFNLSIASKTLHISQPALSQIIKNFEESE
                     DVYLFERYKGRLNGLTPAGERFYVNAEHIINEYKNMMEDLREDSVQFKGKVRIGIPPL
                     ILGIAFSDVVAQLVANNPDIEFDIVEKGAYDLNRMLILQELDYAVLLHPHKIDKSVVT
                     EHVLQEDELTAFLNINHPLAKKDKIDWNDLNEQLLAIFNPTFMIHHKLMQKFTDENVK
                     LKRYIMSGSWDFLLLSTTNSDFITILPSPVHDFFENSKIIEKPFNHPITWKVILCRPK
                     KERYSHVDQHVFKFIIDFFSKKNS"
     gene            complement(55014..55826)
                     /locus_tag="JAM15_04455"
     CDS             complement(55014..55826)
                     /locus_tag="JAM15_04455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6797514.1"
                     /translation="MFTSILKKLKKDKSFAFACITLSIIIILIIASFILNIDSNAIDT
                     TSKLQEPSLKHIFGTDELGRDYFSRALYGGRISLSVGILSMLISVVFGTAVGVISGYI
                     GGKLDQFLMRLVDMLMSIPSFLVLIVLNTYLTPKVSTIILIIGFLSWMEVSRIVRGET
                     LKIKENEYCLAAKATGIKTRNILLRHIVLNLKETIVVAGSLNIANAILTESALSFLGL
                     GIQLPLASWGNMLQDAQRHIFDKLYLAVFPGLLIFLTVMSLTIISKKFSSNT"
     gene            complement(55829..56788)
                     /locus_tag="JAM15_04460"
     CDS             complement(55829..56788)
                     /locus_tag="JAM15_04460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6797515.1"
                     /translation="MLKLILNRVKVLIPMLILISILSFGLLELAPGDPADAYINPLMS
                     SQDIENIRVNMGLDKPVYIRYLNWLKNTLSGNLGISYINHMPVTEQIMEKMGNTFILM
                     GTSLIFSILVAIPLGIFLAVNKNSITSKVSSVFNYIGVSIPSFWIGMILISIFSVKLN
                     IFPSGGMHTIGNDSIGDLVKHLVLPVITLGLYNTAIFTNYVEASVNEQLKKQYVITAR
                     AKGLSEKVILFKHVLKNSLTSLVTILGMSIQKLVTGAFVTEVVFSWPGMGRLMIDSIF
                     SRDYTVIMAITMLSALFLILGNLVADILYLLIDPKIKSSKGGF"
     gene            complement(56894..58453)
                     /locus_tag="JAM15_04465"
     CDS             complement(56894..58453)
                     /locus_tag="JAM15_04465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAT6797516.1"
                     /translation="MKFKKLASLILVSSLMLTFTACASNDKDKSSGSKSGGTVVIPMA
                     SDPDIINGAFANVKEDSLASNIVYAPLYTYEKGNLVNYLAEKVDFKDSKELTIKLKSN
                     LKWHDGKPITAEDVLFTFNTVLDEKQNSPSRQYLLVGEKPVKVEKIDDLTVKITLPTA
                     SESFLYGISKISPIPKHVFEGESNIAKSEKNNNPVGSGAFKFKEWKKGESIVFEKNAD
                     YFGGEPKADSIALKIIPNEASQEAALNNGEISLMKTSAEGYEKAKSKSNLQTYTYSEE
                     RLNYIVFNQNISNMANKEVRQALSYALNRNEMIESAYGKEGSVPAKSILVPEADFYTE
                     EGVEGYDQDTNKAKDLLDKSGVKIDKLKIGYNTGRFGHKNYALVAQQELKKIGIEAEI
                     VPYESKAFFNILFSNSTECDMYVNGYAWGLEPNPYRGMFETGQYCNQTKYSNAEIDAL
                     WEKGFTELNKEKREEIYKQIQQDISKDAPIYTIDYEQNLMAAQKNLKGIKDAKPSPAI
                     LFEDWSKLYVE"
BASE COUNT        22767 a         6886 c        10113 g        18758 t
ORIGIN      
        1 aaaaattccc actttattcc ctactttctc cccattttga ttaaaaaagc atgagataat
       61 agtattgtgg aaataaagat ttccctctca aaactaaata attgctaggt tagtttaaag
      121 ggctaatcta gcaatatgaa cagactaggc agggcgtgag gacactgtta gttcaattct
      181 aactatgttc aaaatctatt gatacactat attaagtatt tgaattgaga ttaaaatctc
      241 atacaatttt gtatcttaat tcagagtcta aaatcgagtg gggcttggta acctcactca
      301 ccatgcaggt actggtattt aatctaggtt cgattcctag aacctgctcc cttaaataat
      361 atgtatctcc cctttgaaaa agactaagtt tgggtaagct tagtctttta tttcttttac
      421 aggtagatat ataaaagcaa agattactta tatctcagac tatcaacaaa aagataatta
      481 cgttgtattt agtttcgaaa aagagttttg attcaataac aattaataat aatttataaa
      541 tttgtactct agtaagagtt cttttttttt agtgaaaatg ctattatttt gtagttgtcg
      601 aatggttttt gaaggatatt gacctttgaa gttgaatttt atactttgga ggggattaaa
      661 atgaattttt gggaaaacat agatgatgaa ctattaagta aagattatat ttgtggatat
      721 tgtggttgtt atatagcaag tcaaaaaggt tatgaaggtt tttttcgtac tggaccagat
      781 gaacagatta gaataggtat atatttatgc cccaaatgtg ttaatccaac atattttgat
      841 aaggataata aacagtatcc aatggctaaa gctggaaatg atgtattaaa tatcaatgac
      901 gaaaggatta aaggtttata tgaagaagct cgaaattcat ttagtgtaaa agcatttaca
      961 tcagtagctc tatgttgtag aaagttatta atgaatgtag cagtatattt aggtgctgaa
     1021 gaaaacagga aatttatatt ttatgttgac tggcttgata gagagaatta catattacct
     1081 aattctaaaa aatgggtaga ccaaataaga aagataggaa atgaggctac tcatgaaatt
     1141 tgtattataa gtaaggaaga tgctgagaaa acattatttt tcactgaaat gttgttgaag
     1201 atggtttatg aatttccagc tatggtagaa taattactga agaagaactc taaccagagt
     1261 tcttttttta ttcccaaaac gacaaacaaa cgaggtggtg atgtgcaaga tgtcaaagaa
     1321 aaggtaaaac aagattacct aaaaggtatg aaacaaaagg aaatatcagc aaagtatgac
     1381 attagtttaa atactttaaa gtcatggatt aaaagataca actgggctag tgaaaaaaag
     1441 aagggtgcac ctaaaaataa aaggggtgca cccataggta ataagaatgc cactggacct
     1501 cctggtaata agaacgctga aaagtttggt ttcttctcaa aatacttacc tgaagaaact
     1561 caagacctaa ttaacgagat aaagaataaa gataaattcg atattctttg ggagcagata
     1621 acaattcaat atgcagcaat aataagagca caaaagataa tgtatgttaa agataaggaa
     1681 gaaatgatta aggaacttaa gaaacatgaa agtacagaaa atggcgagaa gatagaatat
     1741 gaatttcaat ttgcatggga taggcaagca tcttttctta atgcacagag tagggctatg
     1801 agcgagttaa ggagtttgat taaacagtat gatgaaatga ttcataagga ttggaatttg
     1861 gctacagagg agcaaaaaac tagagttgag aagttgaaat gtgaggttgc taacctaaat
     1921 aaagatgata cagataaaga gataactgta agagttatga aagcgagtgg agaaaatgga
     1981 aagtaaattt atatcaaatg accactttta tgattttata ttcaattggg attacaaatt
     2041 ttattttctt gttggaggat atggaagttc aaagagttat catgtagcaa ctaaattaat
     2101 tattaagctt cttgaagaaa aaagaaaagc tttagtggta agagaagtat atgacacaat
     2161 gagagatagt tgtttttctc tattagaaga agttgcagaa agtatgggtt taggagatat
     2221 attatcattt aaaacaagtc ctatgagagt tatatttcca aacggaagta aaataatatt
     2281 taaagggatg gataatccag ctaaattaaa gtcaataaat ggtgtatcta taatatggtt
     2341 ggaagaatgt tcagaggtta aatacactgg ttttaaagaa ctcttaggac gtttgagaca
     2401 tcctagttta tctaatcata taatttgttc aactaatcca attggcgaag ataactggac
     2461 ctataaacat ttctttagag atgaagaaaa agacaggttt gtattagatg atactgtgtt
     2521 atataaaaat agaatagtaa taaaaaataa tacatattat catcattcaa ttgcagatga
     2581 taattttttt ctgcccgaaa gttatataga gcaacttgat gaaatgaaag aatatgacta
     2641 tgacttatac agaatcgcaa gaaaaggaag atttggtata aatggaacta aagtattacc
     2701 acaatttgaa gttatggagc atcaagaagt tataaataaa atatctaaca taccacaaag
     2761 gtattataaa gttggattcg attttggatt tgaaaaatca tacaatgcac ttttaagatt
     2821 agctatagac catgaaaaca aatatttgta tatctattgg gagtactata agaatcaaac
     2881 tacagatgat gtgactgtta aagatattaa agagtttaaa gatactcaag aactaataaa
     2941 agctgatgct gctgaaccta agactataaa atattttaga caacaaggtt ttaatatatc
     3001 tggtgctaag aaatacgctg gaagtagact acaaaatact aagaaggtta agagatttaa
     3061 aaagatttat tgttcaagtg agtgtaaaca tacaataaaa gagttaaaga acctaacata
     3121 cgctacagat aaaaatggaa acttaatata tgatgaattt aatatagacc ctcatacatt
     3181 tagtgctata tggtatgcac ttgatggtta tgaagtgtca gatattaagg agttaaaata
     3241 taataatgat atttacaata aaggcttagg cttgaagaaa aataatatac caaatcaata
     3301 taataagaag ggaggggctg tattttagtg agtataaaaa atatcttgct taatttggat
     3361 gaaaaagaat taaaagatag aaaacatgca gaaagagatt tcttgtttta tttaggtgaa
     3421 tgtagaaata aaacaatggg attattagat gatgattttc taggtcaaag ttggattact
     3481 tttgataatt tagactatgc accttctcag attatagata ataaagtaaa accacttata
     3541 aataaacaaa ctcgttttat gtttggaaaa gaaccaacta taatacttaa agcatatgag
     3601 aaagaagata aagaaacatg tgaggaatta agacaatata ttgattcaat attaaatgcc
     3661 agtaagtttt ggagcaacac actaaaagct tttaagatag caactataac aaaaagagtt
     3721 ttattaagat tagaagctga accaaatcaa cctataaggc tattttatca ttctatggat
     3781 gattttaaat atcaagttga tagtaatgac attacaaaat taaaatctgt tatatttgtt
     3841 agatttgatg cttcaaccat aaaagaagta acagcgaacc aaatatggta tagatatact
     3901 tattacatga aagaaagtag tgttaataac caagaaagtt gttttttaag agtagaaaaa
     3961 tttaaaggtg ataatttatc taagcctatt gaagtaaaag aaagtgatac caagctttct
     4021 aaaataccat gttggataat tgttaatgaa caaagtatta caaatatcac aggcattagt
     4081 gatattgagg atttaaagcc attacaagat acttataata aaagattatc agattttaat
     4141 gactctttaa aatttctaat gtttgggcaa actgttgtag tagatgcgac agaagaaaca
     4201 gttaatgcct gtaagattgc tccgaatgct ttaatggcat taaaaacact tgaagaaggt
     4261 tcagaaaaag gaaaacaagc acaagcatat agagttgaga gtagtttttc aaatgcagac
     4321 ccagtcgact ccttttttaa aagacttgag gatagtatgt acgaaaaact tgcaatccct
     4381 agaccagagc aattacagaa tatacctagt gccaaagctt tgaaatattt atatacggaa
     4441 cttattgcaa ggtgttcgga aaagtggaat gattgggaac ctgcaataag aagtatgtta
     4501 agactaatcg ttgaagcatg tagtaaattt aattgttatg atgattggaa tcatgattgg
     4561 gatgatttaa tgttttctat tgtattaaat aaaaattatc ctattccaga agatgaagaa
     4621 gattcgaaga gattggcact tgaagaagtg aacaataatg ttagaagtca tagaaattat
     4681 ataaaagaat ttggtgatga tgaagattat gaggaagcat ttaatgaagt attggaagat
     4741 aatgaaaaga tacaatcagt agagcaagac caattcagaa aagacgcaga aatagaaatt
     4801 gatgatattg atgaagaatt aaatagtaaa tctaataata gtgatgagta atgaggtgtt
     4861 gttatgaagg acaatactta tacaaagaaa gttcttgaag ctagaaaaaa acttttatta
     4921 ttagataaaa aaatacaatt agagatatta aatgtatata aagatgccag taaaatcatt
     4981 ttaaatgaca ttgctaagaa taaagaatta aatttaagta ccaaatacct aaaaaagcta
     5041 aataaatcaa tcgagaggta tattaatgag ttaaaccaaa gattagtacc tgttgcagaa
     5101 aaaagtgtaa tagaagcttc taatatagct aaagaattac aaatgtatta ctatcaatca
     5161 atagttccaa atacagctat gaaccttgca tgtgatgcta tgtgtataaa gacaactact
     5221 ggcgtggtga aaaaaatagt tgcaggtaac ttttataaag ataaaaggtc attagatagt
     5281 aggatttggg gctatagtaa taaaaataga aaagatattg atagattaat aaaagctaat
     5341 attgcaagag gtgctaatgc aaagacgtta gcaaagagtt tagataatta tgttaatcca
     5401 actaaaagaa cagatgctaa gacgttagaa attggcatga ataaaagtat atcttatcaa
     5461 gctcaaagac ttgctagaac ctctataaca catgcctttg tagaaacaag tgttcaaaat
     5521 gcaataaata atcctttctg tgtaggacta caatggaacc taagctctca acattatatt
     5581 agacaggtga aatggagagg cgaggatgag tgtgatgagt atgcagaaca aaatcgtttt
     5641 gggctaggtg aaggagtttt cccacccgaa aagtatccta ttccacaccc taattgttta
     5701 tgttatccaa ttcaagtgat tgtaccaatt agtgaagctt ctaaaatgat ggagaactgg
     5761 ataggtggag gagataatga tactcttgat agttggtttg atggaataag acatcaaaat
     5821 aatagtgttc caatcattaa aaaacaaaga aataaaaaga ataaaatagc tacaaatagt
     5881 aaagatgata gaattaaaaa gaaccttact aattcaatta agaataagtc aaagaaagca
     5941 cctaaacaag ttcaaaaata tattaacaag tatgtgcaac caagcaaaat actaattgat
     6001 aatagtcaaa aaataccttt tatttattat actaaggttg atttaattgg tattaatcca
     6061 aatattaaag aatttaaatc atataataaa gaagctgctt tacttcatga gtttgcgcat
     6121 agaattgata taaaagaaat taagagctat aataatatta agttccaaaa agctattgaa
     6181 aatagctcta tatatgttat gaagaatatt gaaaacttgc aaagtatata tactaattct
     6241 aatgagttgt acaataatga atttattagt gatatactag gagcattatc taataatgaa
     6301 tttgaggatt tattagcaac tcatagcgaa aaatattgga gtaaaaacag aaataaagag
     6361 aaagaaatat ttgctaattt atttacacta aagtatcaaa ataataaaga aataaatagt
     6421 tttattaaag aacatttaaa tgatttggat aaaatattta atgaattgtt aggagggatt
     6481 tagattgctt gaagaaatga gaaaagataa aaaattgtta gaactaagac gattatataa
     6541 agagaagtat ggtaaaaatg cacctggttt taattatgat gaatataata gttatgctga
     6601 atacaaagaa aaattaaaag aattaataca gaagtaaagt aagcacttat taattaaaga
     6661 ttaatgagtg cttttattat gcctaatttt aaggaggaaa ttgaatgtta gaatatttta
     6721 aaaagatatt tggagatgag gaaggtcaga aaatatatga aaagttatct aaagataagg
     6781 aaaataagct tcttttagac aatattaaaa actctaagta tgttgaaaag acagagttag
     6841 aaaatgctaa taaagagatt aaagagtata aaaagcaaat aggggataga gataagcaat
     6901 taaatgactt gcaaggcaaa gttaaagaca acaaagaatt atctgatgaa attgaaagtc
     6961 ttaaaaatgc aaataaagaa attaaagaaa atgcagaaaa agaaattgag gttttaaaat
     7021 tcaatacagc tcttgaaaga gctattgaaa gttataatcc taaaaatgca aaagctttat
     7081 cagcactaat aaataaggaa aatatcaact ttgtagatgg caaaattatt ggattagatg
     7141 aacaaataaa agcttatcaa caaagtgatt cttatttatt taataatgaa aaaaataaag
     7201 gagatgatga aaatgtagga actggaggac tagaaggagg gacaacatca ttacttgata
     7261 atgataacga aataagtagt ataggtgagt tgctagctaa ctctaaagta aaaagcgaaa
     7321 atatagaagc tcaaaagaaa ttctttggag aagaatagga ggaaaatata tgagtataga
     7381 aaaatctgag atttacatgg gggaaaataa aaccatatta aaatttgcag gaaatttatt
     7441 tcaaaatgta aatattaaag tgaaaaaaac tgatgtagct gtagtagatg gaaaaaggat
     7501 tttaaaagca ggtacattaa tatcaaaaga tggaaaatta gtagatggta caactgttac
     7561 aaatgataaa tcttttggtc tagtatatag aaatatagat tttactcatt caaatggtaa
     7621 tgaaagtatt ccagtactaa tatttgggtt tgtggatgaa aagaacttac catcagttat
     7681 accagaagaa gcaaaacaag caatgaaaat gattatgttt ttataaaata aatattagga
     7741 ggaattaaaa tggattggaa agactttata gactctaagg agatagctaa atatataaaa
     7801 aaattaccac tagaaatgtt aataggcgaa tctttgtttc ctagaaaaaa acaaataggt
     7861 atggacctaa aatatattaa gggagcgaag aaaaaaccag tggtgttaaa acaaagtact
     7921 tttgatgttg ctgtaaaaat aagagcatta aaagctcaaa tagaagttaa atcaaagaga
     7981 atgccatttt ttaaagagag tgttcttgta aatgaagaag atagacaaca gttactttta
     8041 gcttctaaag ctcaaaacaa agaactatta ttaatgataa tttcacaaat atatgataat
     8101 tatttagccc ttgtagatgg tggcgatatg caaatggaaa gaatgagaat gcaggctcta
     8161 gctgatggag taataaatat agtatcagaa gatggagatt tagtatttga ctttgaagtt
     8221 ccaagtaatc ataaagaagt gttaactgga agtgcaacat gggataatcc agatgcagat
     8281 attataggag atattcaaag atggatgaga ataatgagag atgaagggaa gccattacct
     8341 aagcgaatgg taatgacaag caaaaccttt ggatattttg ctaaaaacaa agctattaaa
     8401 ttggatatag ataaagatgg tagagttatt ttaactgatg aaatgattaa aaattatctt
     8461 aaaaataaag ttggtttatc tgttgccata gtaagtggaa catataaatt agaagatgaa
     8521 agtgaggaat cttatttccc tgacaacaaa ataactttta ttccagacgg agatttagga
     8581 aaaacttatt atggcacaac accagaagaa gctgacaaag tatatggttc taaattagat
     8641 tgttctgttg ttagaaccgg tattgctata acaacaatga gattaattga cccagtaaca
     8701 gttcaaacta aggtatcaca attaggtatg ccaagctttg aacgtgctga tgaatgtttc
     8761 ttcgctacag tagcatctta aaaaaggagg atattatggc taaaaagaaa gataacttaa
     8821 tgcaagtaaa agctttagtt tacttaaaat atgataatga ctgttacaaa atagatgata
     8881 tatttgagat tagaaaagct gaccaaaaac ttatggaaga aaatggatat atagaagttt
     8941 taggagaagt tgaagaaaag aataataatg agtttcttaa taaagatggt gagtagatat
     9001 gtctattacc aatttagata aattaaaact taatttgcaa gaagaagagt atccttattt
     9061 tacagatgag caacttgaga tgttattgga atctaatgag aataatgttt taaaagcttc
     9121 atggagaggt tgtttactca aaggcgctac agatgattgc attaaaatag gacctataga
     9181 aactaagagt agcaatagtt catactggtt gtcattagca gatatatata aaactgatta
     9241 tttagaagaa aaatcaaaga atgaaacaac taacacagga tataaaacat ctatggcaag
     9301 agttgatgga caatgagaaa attaagagct gataagataa taaagactat taatcgagga
     9361 atagctttga atcctcaaac aataactata gagcaagaag tgaaaaatat agtagatggg
     9421 gctattgata ttacaaatga agtaaaaaaa ctaacagtag ttatatatcc cgaaaaaact
     9481 aatgatacag taataaatag tgaaactatt ggcacagctt ataaaaataa aaactttggt
     9541 atggttgcag ataaagaagc tgatttaaaa ttgaatactg aaagtgatat aacatttaaa
     9601 tgtatcgaag gtactatgaa attaaactat gtaaatccta ttgtagttga ggaaaagatt
     9661 tgtggatata tatgtggtct tgaaaagata gattagaggt ggtttaatat gagtgtgttt
     9721 actaaggcta taaatgaaat tgatagaaaa aaggctacaa tgccaatttt gtgtatgaat
     9781 atagctttta tgttagaagg agaagctaaa aatagtgcaa aatggactga taggacagga
     9841 aatgcaagac aaggtataac aggaacaagt ttaggtggag gaaatcaata cattgttagg
     9901 ttaggtcatg gagttgacta tggaactgtt ttagaggaag gttcagcacc tcatgttata
     9961 aaaccaagaa atgctaaagc tttgttttgg aatggagctt cacatcctgt aaaacaagta
    10021 caacatcctg gtactaaagg tacacattct ttagagtcta cagtcagtag gaatatgcct
    10081 aaaataggta aattagtaga aggacattgg agtaaataat atgagagcag gaataagaaa
    10141 caccttaatt gagaacatat caaagcttaa agattgttat gaaccaactg tacctaataa
    10201 aaagactata aaaccatatg ctgtaattgt tcaaggcgaa gattctgaca gcgagggcga
    10261 ggttataggt tttagaagaa acataaatat ttggttatat gagaaaagga ctacatttaa
    10321 taaactagat gaacttacaa aagaagttat agaaacatta gattttaaaa ctataacaga
    10381 tgatactact aacgaggtat ttacatgtat ttatgagggt gcagttggtc aagatgtcat
    10441 agatgaagaa tgggaagcta taataagatg tctaaggttt agtgtaatag ctttagatga
    10501 taaagaggat ataactagtg atagatgggt agaagctcta tctaagtaca caaaagattt
    10561 attagaaatc gagagttaca aagataattg gaagaaaaac tttatagctc catgtgcatt
    10621 atggcgaact acacatattg aaaataaaag aattaactat catttaattg agattactaa
    10681 aactatgaaa tgtcatgttg ttagcaaaaa taaggatgaa atagttaagc ttcttgaaga
    10741 attagagact aagctaataa tagataagag agtaagactt agagaagata aaaatatgta
    10801 tttaactctt gtaagtgtag ttgaagatag agaatcagac atgttttcta atggtcaatt
    10861 aactgtagta ttcaaaatga taggtaagat aaaaagagaa ggacctatta tgaataagat
    10921 ttatagtaat ggaaatttaa aataggaggt gcaaggattg gctgaagcaa ttaataaaaa
    10981 gactaatata agtaagcagg aagaaaaata ttcaaaagaa gatttcttaa aaaatagtga
    11041 agcacttggc tacaagaaag aagtagttgc aggtgcttta tttaattgta agaaagatga
    11101 acttacaaaa tcagagtttg agaaagtaat aaaagatttc ttagaaagag aggtgaagta
    11161 aaatggcaac tggcacatgg aatgaaaaag agaaaaaaga tatacctggt ttttataaca
    11221 ggttcaagac tcaagcagaa aagtctacaa atacaggttt aaagggtaga ttagcaatgc
    11281 ctattagggc taattgggga gatgtaggta aggtaataac aataaaaaat gatttgagac
    11341 aacttaaaac tttatttggt gatgatatga actattcagc atataagtta ggtaaattag
    11401 ctttattagg gaatgtaaag gaattacttt tatataggct tgtagatgga aatcaaaaga
    11461 agggcacatt aacactaaaa gatactacag aaaatactgc aaaagatgta attaagctag
    11521 aaactaagta tccaactagc agaaatttta atgtaacaat aaaatccaat ttagtggatt
    11581 cagataaaaa ggattttatt ttctttgaag gaactaagca attatttagt tcaagtgtca
    11641 aaggtactat agatgaaata gtgctagaaa taaactctaa tttagataat gagtatgtaa
    11701 ttgcaactaa agtagctgat agtgatacaa cattagcaaa cttagtaaat gtagcacttg
    11761 agggtggaaa tgatggttgt acatctataa caaatgagtc ttatctaaaa gcattagaag
    11821 aatttgagag atatagtttt gattcttttg tacttgatgg tgtagctgag gaagctttgc
    11881 aggaaactac aaaaacttgg gtagctaaaa ataaagaatt aggaaaagac atactacttt
    11941 ttctaggtgg gaaaaaagag gataatataa aacagattaa tgataaatca aaaagtttta
    12001 atgatgaaaa tatagctaac gttgggagtt cagcttatta tgaaaatgta aaatatacac
    12061 ctagcgaagt agctgtttat ataggagcat tagcagtaag caaaggcata acaggtagta
    12121 tatgtaatgc taagactata tttgaagaag tagaaccacg attaagtcaa tcagaagtta
    12181 aagagtgttt aaagtcggga acattaatac ttgattttga tgatggagac gtgattatag
    12241 ttgatgatgt aaatacattt aaaaagtatg tagatgataa gaatgaagct atgggatata
    12301 tctctaatat tatgtttatt aacactataa ataaagatac ttcattgaaa agaaaagagt
    12361 ttgtagggaa aatatttaat gatgcgacag ggcagacaac tgttatatgc gcattaaaga
    12421 aatattttga agaattgatg tcacagggcg tcatatcaga atttaatgtt gatatagata
    12481 cagaacttca agcaaccgcc aaagcagatg agttttattg gaaatgggat gcggttaagg
    12541 ttgatgtgat gaaaaaaata tatggtactg gttatttagg ataaaggagg ttataaagta
    12601 tggggaaata tgatgaaaat attatagatg ctgcaaatgt tgttgatggt tcaaatgcta
    12661 gaataataat tgatggagaa gaagaaggat atggaacaga atttacagct gaggtagaaa
    12721 atgataaaaa gacttttaga gtaattggtt gcaaatggga acttaataaa gcatctactc
    12781 aaaaaggtac tttctctttt actgtactta aaactacgtc taaatggatt aaaaaaggat
    12841 ttaataaatt tgaaataatt acagaaatag aaaatcctgg gctagttgga tatgaaagaa
    12901 ttagatataa aaattgtatg gtagataaaa tacaactagc aagcataaaa tctgatgaaa
    12961 atatagaaat acaaatagat ggaacttttg aaggatatga gttgttagat gaaatagcat
    13021 aataaataaa tttaagctac acgtaattaa ttttatgtgt agctttttat aaaactataa
    13081 aattggagga agttaaaaat ggcaaactta gataaagaat ttttaaatga agtaatagaa
    13141 gaagaaagag agcttactaa agatgaaata gcaaagcagc aagaagataa tataattatg
    13201 aaattgacag aggatgctat attacctgaa aaaactattt ttgtaaaaag gttagatata
    13261 ccactcacac ttagagcttt aacagaaaaa gagataagtg cattgcagaa aaaatataca
    13321 aaagttacga aagtaagggg tagaagggaa agtaaactaa tggaagatga atttaatata
    13381 gctctaatag aaaaagctac tatagttcct aattttagtg atgcaaggct tcttaattct
    13441 atgaatgttt ctagtggggt ggaatttata agaagaaagt ttttagcagg tgaaatcgca
    13501 ttaattagcg atgaagtact agagttatct ggattttatg aagaattaag tgatgatgat
    13561 ataaaaaact aataaaaaga ggtggggaga ttactatttt atataacgca tatgttaaac
    13621 atagtgttct tcctgaagat tttctaaaaa gagagaaaac acctcaacag cttcttagag
    13681 tttttactca acatgaaata gagcaagaaa acaaagctat gaaaaagaaa taaaatttaa
    13741 accgaaagtg aggtgagaga aatagctaaa aaagagatgt accacattga tgttgttatt
    13801 gatattacag gagatgaaca aactaaaaat aaattaagtg ctatggaaag atacactaaa
    13861 cagacagaaa agagaatgaa agcacttaat aggataaaag ctaatccagt tatccaagct
    13921 caagataaaa catctagtgt tgtaaataga attagtaaca acttaaaaag agtgggtaga
    13981 actatatcta caactataaa cgcaaaagat agagcatcta gcgttgtaaa tagagtcaaa
    14041 aataaagtaa atagtttact tacaagtaga caaagagaag ttttgttaaa agctagagat
    14101 aaagctagtc aaattgtaga taaagtaaag gcaaagatgc aaaatttgac tgcggctaca
    14161 ataattagtt taaatatgaa agctgaccca gctttaagag ttatttctca aactagaagt
    14221 aaattaggag aactcaaaaa caatacaata ataaatatta aagcaaaagg ggaagaagca
    14281 ttaaatacta tttctcgtac taagagtaaa ttacaagagt tttctaataa gacttatcaa
    14341 gcaattgtaa aattaaaaga tgaagctagt ccaacattga gtggcttaga tggtaagata
    14401 agttctttta taagtagtac tattagtaag tttacacaat tagcagtaac agcaacaacc
    14461 ttaattggtg gcattggagt aggaagtgct ataaaaggat ttgcagattt tgagcaggca
    14521 atgaaaaatg cacaagctgt atcaagtgca aattcaaaag aaatggcaga aatgactgca
    14581 atggcaagag aaatgggtcg tacaactagc tttactgcta aagatgcagg aaatgctatg
    14641 tattttatgg ggatggctgg atggaaaagc aaagaaatga ttgctggttt accaggtatt
    14701 ttgaatttgg cagcaacagg tcaaacggat ttagctttaa cagcagatat tgtgactgat
    14761 ggtttaactg ctttagggct aactgcaaaa gacacaggaa tgttcgttga tgttatggca
    14821 gcaacagtta caaactctaa cacagacata gaaagaatgg gtgaaacttt taaatatatg
    14881 ggaagtgttg gaggagcatt aggtgtttct atgaaagatt tatcacttgc gactgggttg
    14941 atggcgagtg catctgtcaa aggtagataa gactgccgtt ctaaatagtg atgtttagaa
    15001 ttattatcga gcaaaatcgg tgaaggctaa gttgaaaaat atgttaatac cgaggtaact
    15061 aattagatta caaataggct aattagaacc gtagagcgta ggaagtgaat aaatataatc
    15121 ttcccaagag tgttcgacac ctttcaagtt aaggtgaaaa tgtacgccga actatatgga
    15181 aacatataga actagaggat aaaaagcttc taggataaca gatttgagta tggcaggtac
    15241 agcacttaga ggtggtttag ttagattaat aaaaccaccc gctgaggcac agaaagctat
    15301 gaataaatat ggaatagaaa taaagaaaac aaaagatggt aatttagatt tagctagtac
    15361 aattgttgga cttagagaaa aattaggagg acttgaaggc gtacaaaaga gtgctgcaat
    15421 aagtagtata ttcggtcgta ccgcaatggc aggttgggcg gccgtagtaa atgcaagtga
    15481 aaaagatttt aataaattaa caacagctat tgcagagagt gaaggagaag ctaagagaat
    15541 tgctgacatg aaattagaca ctttatcagg tcaatttact attttaaaaa gcgctattga
    15601 tgatgttaga atatcagtag ggcagaaact aggaaaaatt acaagaggtt ttgttgagca
    15661 actaacaaaa gatatgccta aaatagggga taaaattgtt ggttttgtaa gtggttttat
    15721 taaaaatttt gataaaatta aaagtgtttt acaaagtgtg atttctatta ttggtggtgt
    15781 tgttgctgga tttatggctt ttaaagcttt aacagtaatt tctagtgtaa taagtataat
    15841 tacaaagata gctacagcat caacactaat tgggggaata gttgggattc ttagacctat
    15901 tggtgcaata gttttagcca taggtgtgtt agcaggaaca tttttacttg cttatcaaaa
    15961 atctgaaacg tttaggagca gtattaaaaa cataggaaaa tctatatcta attttttaaa
    16021 acctttaaat ccttttatag aacaaataaa aagtaaattt aaagaactta taagtgcgtt
    16081 aaaacctttg tttttaactt tttctaaatt aagctcaatg tttataaatg cattatcacc
    16141 agttataaaa tttttagcaa cagtttttat aataaaattt atatattcgt tcaatgtgat
    16201 tattaataag ataatagcta tagtgaatac aataacagga gtagtaaatg gattaataga
    16261 tgtatttaaa ggaatagctg atatagctaa aggatttata aatggagata tgagtcaagt
    16321 tgctaatggg tttaaaacta tttttaaagg ggttataaat attgttaaat cattatggag
    16381 tggattaata gattttgtga catcaccaat ccaagctgta gtcgatattt tggatactaa
    16441 gtttggtaaa aaagtggaag gtataaagaa aaaatggaat gaattaaaag atttcttaaa
    16501 aaatcctgct aaagtagctc caaaagttca gtcagttaat ttatctagtg aaaaagcatc
    16561 aaatgagtta caaacttcat cgaatggagc aaaagcatat ataaactcat taggtcaaaa
    16621 aataggcgaa ggtattggga aaattgaaga gaaatttgga gaactcaaaa catctgcaac
    16681 agaagtattc aataatatag taacttttat aggtggcaaa gcaacagaat taaaaaataa
    16741 acttttagaa ggcataaaac ctgctataga cacctttaaa gaatcattaa gtaatttaaa
    16801 agaaactttt ggaggttctt tagatagtat aaaagaagct ttcggaggtt taaaaactgt
    16861 atttgacgaa aatattaaaa caccttttga aaatctaaag caaaaagttt tagaaacgaa
    16921 agaaagttta aaagcagttt ttgataactt aaaatctagt tttgcagagt taggaaaagc
    16981 tctcgaacca ataaaagaga catttagtgg aataaaagat ttcttttcaa atttatttaa
    17041 gcctgttaaa gatgatggaa caactaaaac aactaaaact aatatggatg agttaaaaca
    17101 atcaacacaa agtgtaggaa catctttcaa agagctagga aatgctttca atcaattaaa
    17161 agaagcagca aaacctttta tagactattt aaagcagata aaagattcct tagtatctac
    17221 tttcggagat atagggggag ggttacttaa aggtgtagcg acctctatag ttttagttat
    17281 aacttctgtt attaatgcaa ttgcatccat tataaacgct gtggcaggtg ctataaaagg
    17341 tgtaattgat atagtaaaag gaatattcga aatcataggt gggataatta gtggtgatgg
    17401 cgaaaaaata aaacaaggat tttctgatgt tctcggagga attggggaag tggttaagtc
    17461 tttatgggaa ggtataaaag gagttttagg agcgccactt aaagctgttg tagattttgt
    17521 aagtaatgga ttttcagaaa aagtgggtca ggtaaaacaa tggtgggctg acttaaaagc
    17581 taatgtaagt caaaaaataa gtggctttgt tagttttata agtaatggtt ttcaacaaaa
    17641 agttcaacaa gttggaatgt ggtggcaagg gcttaaagta aaattatctg gcaaaataag
    17701 tggatttgta agtcttgtag aaaatggatt taaaagtaaa gtggattcaa ttaaatcagc
    17761 gtgggattct cttaaaaaga aactttctac caaaataacc ggttttgtaa gtatagtaaa
    17821 gagtggagta agcaatatac tagaccattt tgcagatggt ggtgttgcaa gtaaaccaag
    17881 tatttgtgga gaagcaggtc ctgaaatggt tattcctctt tctaataata agagaagtag
    17941 agcattaagt ttgtataaac aagcaggaga gatgcttgga actaaagcaa gtaataatgt
    18001 aattccaatt tctcagaaat taggaactag ctttaattct acaagtagtg ttcaaaatag
    18061 tacttctaat attattaata atgttaggga ttttcctact agacaagaag aatttaataa
    18121 tacagaaaat agaatttatc aagaagctca accacaaaat ataatttcta gtggaagtaa
    18181 tgcgattaat gttggtggaa tatctataaa tgttcaaggt aacaataaca gagaagaaat
    18241 gatacaagaa atattgtatc aagtagaaag cggattaaga gaagcattag aagacattag
    18301 ataattgtcg aattattgtt aaaaaaatcc tccttataga tgctataatt taattataaa
    18361 tcatgtgagg gggattttta ataatgtggg ataagtttaa aagtctaaac gtttttttaa
    18421 agatacttat agtaattata gctattggta tgttaccagc aacattattt tttctatcaa
    18481 tagttctttt tgttacactt tttaaaaaga aaaaaaagat tgcatgtata atgtctctta
    18541 ttttagttgc tttaacattt aattttgcga atttttggta ctcaatggat acaactgtta
    18601 ctgccagtaa tacaaaaacg gaagaaacaa aaaatactga taaaaagaaa ttggaagaga
    18661 aaaaaaccaa agaggaagct gataagaaga aggagcaaga agaacagaaa aaacaagaag
    18721 aattaaaaaa agcagaagaa cagaaaaaac aagaagaaaa gaaagtacaa actgaacaac
    18781 aaaaaaaaga tgaagaagca aaaaaaatag cagatgagaa gaaaaagcaa gaagataatg
    18841 aaaaaaaagc acaagcagaa caaactaaaa agaatgaact tgtgaaaaaa ctagaaacat
    18901 atgaaaatat atatttaatg attcctgcga gtatagaaga aaaatcagct tcaaataatg
    18961 cacttgagct acaaaaaacc ttttcgacag ggagagatgt agcatcaaaa tgttggcaag
    19021 agctaggtga tttaaaagat aaatatagca ctgaatcaaa tgaatataaa gctatacaaa
    19081 acttgcaatt agcatttttc gtggtaaaag atgcgtgtaa aaatggaata aaatatttag
    19141 acaaaaatga atacaaatat tatgagaaat atgaaaaaaa ttgtaacgaa gcaggtgctt
    19201 ggtatagtga ttttgtaact ttaaaagaga aaattaaata aaaaaaatta aaataaatat
    19261 aaaaacacct actaattagt tggtgttttt aatatgcaat taattaaatg aggtgatagc
    19321 ttggtaatag acatatacct aaaaaatgaa aaagaaaaaa tagatttaca ttttccggtt
    19381 aatccacttg atagtttatc tataaagaaa gaaaaaagat ttgaaactgt tgatatagtg
    19441 aatttaggtg aatttgacat taaaaaagaa ggagagaaga taagagaaat atcattcaaa
    19501 accttcttac caaacttata tgatgcttct tattgtagat acagtgagtt aaaaaatcca
    19561 attgaaatag ttgcaatgct tgaaaaatgg gtagaccaag ccgaacctct aagacttatt
    19621 ataactggtt ttggttacaa tggattagtt acaatatcta gttttagcaa tactcaaaca
    19681 gcaggaagag aagaagatag agacattgag ataacattta gaacttatag agaattgaag
    19741 atagagacat taaaaaaaga aactaaaagt aatactaaaa cagatttaaa agacaataga
    19801 cctaatactc aaactaaatc taaaatatat acagttacat ctaaagatac attgtggagc
    19861 attgcaaaga aatttttagg taaaggttca aggtggaaag agatttataa tatccccgaa
    19921 aataaaaaag ttattggtaa aaatccaaat gtaataaaaa aaggacaaaa gttggtgata
    19981 ccttctaaat gaaaataata ttaaatggaa aatatgatat tgcaaatttt aacgaaggaa
    20041 taacattaag tgaggctata gacggagttg catacaagat ggatgtatca ttagtagaac
    20101 ctaaacaact tcaagatata ggaattaaaa aaggtgataa aatagttcta attgacattg
    20161 catatgagag taaaaaagaa gaaaccatat ttgatggagt catatgggaa actagaagaa
    20221 gtgaaaagag taagaaactg acattgtctt gtagagaaag aacagtttac atggaagaat
    20281 cagaagaaca atatagtttt aaagaaaata cagcaacaca gaggattgag tactactgta
    20341 agcaatggaa tataccttat tacaacttag ctaatacagg gaagaaactt gctaaagtaa
    20401 tacataagac aaatatctta gatatgatta aaaaagactt aaaagaaaca gctagtaagg
    20461 gtggagattt atttagagta agaatggata ataagctgaa attatttaag cttggaacta
    20521 atgcaattgt atataaatta gatagtatat tagaagatgc aaactttaca agtggtttta
    20581 atgatgcagt aacgagtgta aaagtgctag gtaagagtaa agatgaaaat acaaaagcac
    20641 ctataattgg aacatataaa aaggactcag acaaatatgg aacactacaa aagattaaac
    20701 aagatgaaaa gataactaat gcaaaagaag ctaagaaagc agcagaagca atgtttaata
    20761 gtggagaaga aacaataagt gttgattgtg tagtagatat aaacagaata agagcaggtg
    20821 acaaggtatc tctaaaagga agagaatact atgttataga tgtcactcat acattagact
    20881 ctacgccaaa aatgaagctc aatataggaa ctttagatta tataaggagg aaattttata
    20941 acaatgactg atgctagatt taatggagtt gctagaatat taaaagaaaa aatgaataaa
    21001 agtgttaatg atggagtctt tggaatgggt tgttcacttg cagaaataac aacaaatggt
    21061 cttaaagtaa atggttataa agatgaaata caagattatt tagtattaga gaatttaacc
    21121 ttaaaagagg attattttgc tttttcagat gaggctttaa gtggagaata tagacataaa
    21181 cataaaatag aaactccaca agaattaaat ccactagata taggtgataa tgtgttagta
    21241 gctattatgg gggctgaatt tgtagtaatt gggagggttg taaatgccaa acctatttcc
    21301 gcagaatgaa acttttgaaa ctgtagaatt aaaaaataat aataaaaatg aactggacct
    21361 aaaggagtct tttttatttg actttataaa aggtgaattt gtcaaaaatg cagatggaac
    21421 attaaaaaga tgtaacaagg tagaggcata taaacaatgg tgtcaaaaag ctatattaac
    21481 acctagatac aaacggtcag cttattctag tgtatatgga agtgaaataa aagacttaat
    21541 tgctagtaat ctatctcaaa gtgctaaaga acttgaaata tctaggttaa taaaagaaac
    21601 tattttagtt catccatata caaaagaagt gagtaatttt atattcaatt ggcttgaaaa
    21661 tagtagcctt gttaattatg aatttgatgt actaacaata gatgatgaaa atatagtaat
    21721 tgatggcaat ataaaaaggt aggtgattat atggaaagag aactacctat accagtattt
    21781 ttaacggaag atgaagaagc aatacacgaa agaatgttaa gtaactttca agatgtttct
    21841 atcttagaag gagattttgt ttatgatgca acaagaccta cagcagagca gatagctgaa
    21901 ttaaaacaat tagggctaca aaataattta aagattgcat ttcctcagac ctcttatgga
    21961 acttatttag agtggcttgg cgaatgtaag ggagtattta aaaatcaacc aactaaatcg
    22021 gttggcatgg ttacatttac aggtgtacaa ggaactatca ttacaaaagg aactatagta
    22081 actactgttg caactgatga aaagcagagt atagagtttg agcttcttga aactaaaact
    22141 ataggagaaa gtgaaacagt agatattaaa gcagaatgta gagaaactgg aactatagga
    22201 aatgtatctc aaaatactgt aactgttcta ttaggttcta ttaatgggat taaatctgtt
    22261 actaataaag aaagctttaa gggtggaaca gatatagaag atgaagaaca ttttagagaa
    22321 agagttcttg tagcagagca agaagacaaa cttagtggag ctaattcaga ttatattcgt
    22381 tgggctaaag aagtagatgg agtaggatat gcttatgtag ttgctgaatg gaatggagca
    22441 gggacagtaa aagtattaat actagataaa aatagaaaag cagcaacaca agaattgata
    22501 gataaagttc aagaatatat atatccatta aatgtatcag aaggagaaaa tagagatggg
    22561 aaagctccta taggtgctat tgtaactata gctactccac gaacattact aattaatgta
    22621 aaagctagtt ttgtgttttc aaatggattt agtcaagaaa ctgtgctaaa tatcttaaaa
    22681 aataaaatag acaaatacct agataaaata gatattggag gtactgtttc ttataatgca
    22741 atttattcac taacaggttc tatgatgctt gcagatgaag gaatacaaga tttttctaac
    22801 ttgacaataa atgatggaac aacaaatatt attttaaatg accaagtcgt tggaataggt
    22861 gagatagtta acgaggtgat agcgtgataa cttctaaaaa aggtagagaa atgcttctta
    22921 cattgtcacc tatatatgag caaagtttaa ttatgaactc tatatatgaa gctataggaa
    22981 gtgaatttga taatttagag ttattaaata aagaaataga gttacaatta tttcctcaga
    23041 ctgcaacatg gggtttaaat ttttgggaaa atagagtagg tttatctact aatctagatg
    23101 aagatataga aactagaaga agaaaagtca ttgctaagct tcaaatgaaa tatattgtta
    23161 atccaagccg actagcaact ataataaaga gctatactgg tacagatgtc tatataaaag
    23221 aagatatagc tccatacact tttaaagtaa ctgctaatgt agatgatgtt attaattatg
    23281 aagatttcaa atatataaca aataaaacta agccaagtca tcttcattgg atgccttctt
    23341 ttgcactcaa atttacagat atagaaaagt ttgaggtaaa gatggttaat cgaatgttta
    23401 tagactttag aggaaatata agtaattttt tagatggtat gtggttacta aatggtagta
    23461 agaatttgag tgcttatata ctttatcatg aaccaataag cttaaacatg aaaaataagt
    23521 tatttataaa agaaagtgaa gtatttacaa atattaaaat aattattaaa aagaatttat
    23581 actatctaaa tgggatagag gtattaaatg ggaataaact gcttaatgca gaattaagag
    23641 aggaggtgtt ataagtatgg caaatgcagt gacaacagat attgcaagac aaaaaatgtg
    23701 taaagctcga gcaggtgata taacattacc tactatagtt agcatggtgt ttggagatgg
    23761 aggaattggg aatgatggaa ctccaatagc cccactttca agtgatacag cattaaaaag
    23821 tgaagtgttt agaaaagaca tagaaaatta tatatatcca gttccaacta cttgtagata
    23881 ttcaactact ttattaaaaa atgaagcaga aggaaaaaat ataagtgaaa taggtctaat
    23941 agattcagat ggagatttaa ttgcgataaa gacttttggt aataagtata aagatagtga
    24001 tatggaaatg gtgtttcaga tagatgacga gttctaggag gtgaataaat gcctaataaa
    24061 ttaaatttta ataatgaaat agaagaatat ttaataacta caccagctca tgcaaatgag
    24121 ttcaataaaa gacaaaatag tttgcttgaa aatgataagt atttaaataa taaaatagat
    24181 ataacaaaaa cagagttaaa cactagaatt gacacagaaa atgagaaaca aaatattaag
    24241 attgacaata tcattgcagg gggagttaat gtatctcata cacatatcat agaggtggct
    24301 gattgggttt taaatagtga aactaatatg tatgaagtaa ctatagaaaa tccacttttg
    24361 actgaaagaa tattaatatc tatgtacaat gaaaacggag atacacttgt ccctgatgcg
    24421 acagtaaaag ataataatat aattgtcaga agtactgaaa ataataggac attcgtatat
    24481 ttgataaatg gaaatgcaca aactagttta attaatgtga atattgatga taacagagtg
    24541 tctgaaatga ccgcttattc ttctaagaaa atcgaggata gattggttaa tatagaagaa
    24601 aaattgaatg gaaatttatc tactattgca acgagtgtaa atgagttgat aacttattgt
    24661 tagagaggag agtgaaaaat ggctacagaa tggaatttta attttaaagc agaaccacaa
    24721 cctattactc taaaagctgg tagatacaaa ttagaatgtt ggggggcatg tggtggtaaa
    24781 aaaggtgtaa ctgctggtaa tggtggttta ggtggttatg ctaaaggtga gcttacctta
    24841 aaaaaagaaa ctattcttaa tgtttatgtt ggtgaacagg gcagagatgg ttctaatgcg
    24901 tggactatat ttaatggtgg tggttttggt ggagtttcaa ctggtggtgg tgctactgat
    24961 ataagactta ttgctggtga ttggggttct caaataggtt tattatctcg tataattgtt
    25021 gctggtggtg gtggtggaca tgattctgat acatcaacag gcaattatag tagtgctggt
    25081 ggtggaacta aaggtaataa tggtgtttct acattgtctt atcatacacc aggggctaca
    25141 caatatgatg gtggtagggg tgctgatata cattgtgatg gttcgttttg cttaggtggt
    25201 ggtacgatta cttatttaca atattgtaaa tgcggtggcg gtggtggatg gtttggtggc
    25261 gcaggtagca aagttagtag tagcgcaggt ggtggaagtg gttatgtatt aactaaagat
    25321 agttataaac ctgctgggta tacaccaact tctgaatatt atatgataaa tcctaaccta
    25381 gcaactggga ataatactac taaaggacat ggttacgcta aaataacatt acttcaatca
    25441 ttaccgtttt taaatgtaat atcttataat tcaactactg caacattcaa agcagaccat
    25501 acagaccctg cattattaac taaaatagaa tgctttatag atgatacact aaaagaaact
    25561 ataacagaag atttaacaac agagaaaaca attaattata cattagaaga taatgcacta
    25621 cacacactta aaatagtcgt tacagacagt gcaaatgcta cagtagaaaa agtattaagt
    25681 ataagtaaaa atataatgcc attacccgaa aatgtaaatt taaatgatat atctacaaaa
    25741 ttagttgagg taagtacagg atttaaagtt ggtaaaacaa gtattataaa tactttagca
    25801 ttaaagaata tagaagcaag tttaaataat acattagtcg agttatcaga gaagattaaa
    25861 acttcttttg atagttcaga cgctagtgtg caggatttga tgaatcagtt aacacaagct
    25921 aataatacta tatcacagtt aaatactcaa ataaatggat taaattctaa atataaatat
    25981 gcttacagca cggatgttac attgcattgg tatgttgatt gtggatttag acccgatttt
    26041 gttatttatg attgccagac tacacgaggt cgactttttg ttatattaac tccttcaata
    26101 tatgcttgtt ttgacacttc taatagacgt tggagcatta tctcctctga ttatgaaaac
    26161 tcttacgctt attcaaaaaa taatattaat agttattatg gcactgaaat taggaacact
    26221 ggatttaatt gttctgctat gcctggagat tctttaaatg ataaatatta tttttattat
    26281 gctattaaat gtttatagga ggtttaatat atgaaaaata taggaagaat agttttttat
    26341 gataatgata caggggatat attaatgttt tatggggaaa aaacagtaag cgatagtata
    26401 aatattaata tccctaaaat agattctatt gagttgccat atggaagtat agattatact
    26461 agaaatagac tgataggtat aaatgtagaa acaaaggagc ctattttaga agaaataaaa
    26521 atagaattga cagaagaaga aaagaaaata caagagttag aaaatcaatt actaattgca
    26581 gaaaatgaga aagtaggagg attattataa tgaatataaa taatgttgta gtaagaatat
    26641 tagcagagag aatattaaat aagggattaa atcctctaaa aaatagagta tttgaacttg
    26701 atgatgttac taacacagag tataggatag cagttgaaaa ctacattata gaacatagtg
    26761 gagtagtaga aggaacacaa cctacaaaat aggtaatgtt ccttttttta tttcaattaa
    26821 ttaggaggct tacatgaatg aagaagttat aaaagaaaaa ataaaacgaa atgaaataag
    26881 aataaacaga cacagtgatg aaatagacga attaaagata gcaaatatag agtctaaagc
    26941 agagttaaag gcactatgtg agaatttaaa ctcacttaca agtatgctca aatggctgat
    27001 aggaacaatg attacaacac ttgtaggatt ctttatattt gccatacaga aaggaatatt
    27061 ttaattaatt aggaggataa aaaatggata atttaataag ttttataccc gagcagttgc
    27121 taattttagt agctgctctc tctattatag gcaaaggttg caaaaaatat aaacaattag
    27181 acaataaata cattccaatt atattacttg tgttaggaat cggattttct atttggatgc
    27241 taggatttag tcctaacgca gtcttacagg gaataatttg ttggggaata tcaataggta
    27301 taaatcaaac ttacaaacag ctaaaggagg aaaataaata atgaaaatat gtataacagt
    27361 aggacatagt attttaaaaa gcggagcatg tacttctgct gatggagtag ttaacgagta
    27421 tcaatataat aaatctcttg caccaatatt ggcagataca ttcagaaaag aaggacataa
    27481 ggtagatgta ataatatgcc ccgaaaagca gtttaaaact aagagtgagg aaaagtctta
    27541 taaaatacct agagttaata gtggaggata tgacttactt atagagttgc atttaaatgc
    27601 aagtgatggt caaggaaaag gttcagaagt tctatattat agtaataaag gtttagaata
    27661 tgcaactaga atatgtaata agctaggtac agtatttaaa aatagaggtg ctaaattaga
    27721 taaaagatta tatatcttaa atagttcaaa gcctacagca gtattaattg aaagtttctt
    27781 ctgtgataat aaagaagatt atgataaagc taagaaacta ggtcatgaag gtattgctaa
    27841 gttaattgta gaaggtgtat taaataaaaa tataaataat gagggagtta aacagatgta
    27901 caaacataca atcatttatg atggagaagt tgataagatc cctgcaactg tagttggttg
    27961 gggttataat gatgggaaaa tattaatatg tgacataaaa gactatgtac caggtcagac
    28021 acaaaatctg tatatcgtag gtggaggagc atgtaataag ataagttcta taactaaaga
    28081 aagatatact gtgataaaag gtaatgatag atttgatact ctttataaag cattagattt
    28141 tatcaaataa gaagttagaa ataaaaaact gagaaaaaat tattattaga aaatatgaaa
    28201 aaatgaattt gaagagaagg atcattaaca tgaataaaaa attaaaaaaa tattttataa
    28261 atatttcttt tgttaaaaat tgtaaaaaaa aatatatttt atgcaagtag aatatagttt
    28321 cattgataaa atataatttt agactgtaca tttgtagtat ttataatata aatatttcgt
    28381 taatttactt tactattata gaatgaaaaa aagattgaaa tatgtctgaa tatagaattt
    28441 gaaaaataaa aattaaatga tataattaag gagattataa ttaaaagagg aaaaggggga
    28501 catattatta tgtttaaaaa agcaaaaagg ataattacat tagcagcaat gatatcaatg
    28561 gttggaggaa gtattttaat tgggcatgca gatgaagaaa atacatactc tccagaaaca
    28621 ggagaattac cttatcaagg tttagaatta aacgtaagcc caacaacacg tagcgcagaa
    28681 cctagaacat atacttataa gtattcaggg gaatttaaga attatactca atcaggtgca
    28741 tttgtatcaa caggacgcca aaaaataata gatggctatc aacgaactaa gacagctaca
    28801 gcttcaacag gtgtacaata tcaaataata acaaaacaag gttcaaaatt aaaatatgta
    28861 actagaacag gagtttataa tggaaatctt tctatagatt tgtctcacaa taatacagtt
    28921 gggtctgacc gtaaacttag attagctaac tattacaatt tatcatttga tgatccaaat
    28981 gcaccagtac aatctgcatc aggtcaattt aactatcttt actaaaatac aataaaatat
    29041 ttaataataa agaggcttat ccaaatgtaa agaagcctct ttattcaaag gatagtatta
    29101 ttatttattt aaaatttatt atctaagcag attaataata agtatattga agctgagata
    29161 aattattaat ataaacactt ttaatagtgt cattaagtat cgggataagt gttatatgca
    29221 taattattga tattatttgc actgaatata tactaattat aaaattcaga aaaatatata
    29281 tgcttaaatt aaggattatt ttttaaaata ggggcatgaa tatgaaaaaa ttgactatat
    29341 tattgggagc attactcata tgttcagtat taatattttc tcaaaataga gaaagtataa
    29401 atggattagt tttgtataaa agtgaagttt ctagttatga tactttaaaa aattatttaa
    29461 aaaaagaatt aaatataaat ctacaggtag actatgttat agatgataat gaaatttcaa
    29521 aagaacatga tttttgggaa tatcctagag ttcaattaat aaacaaatta aataataata
    29581 acattgattt actattagat attccaaatg aatatttaag agattctatg aaagatgaaa
    29641 aattattaaa gttagataat tatatagata cacacaacat ttatcctgca ataatagata
    29701 aatccaagga aataggtaat ggtaatatgt attttatctc accatacttt tcatcaaatt
    29761 ttattatgat aaatgaaaat ctctttgaaa agttaaatat acctattcca aacgaaataa
    29821 aatcttggca agatgtttta aaattattaa aggatattaa aagttcaata aaagataata
    29881 atgttagtga tatttatcct ttgtcattag gtatgaatgg tacagaaagc ttttttcagg
    29941 attttgaagt tctaacaaca ccatttaatt tatcagtaaa atcagaagga actatttatg
    30001 atgatgataa atggatggat gtatttgcat tttttatgaa tctgtataaa gattatggta
    30061 tacataaaac aataaataca gctgatatgt tcattgatga caagatagct atgaaatttg
    30121 ttcaaggaat tgaaataatg aattataaag aatctatggg taaatataaa gtttttgaaa
    30181 ttccttctta taaagagttt aaagataaaa tttatctaaa cactacagac atatcaatac
    30241 ccgctaacgc tcctaacaaa gaaaatgcac taaaaatatt aaatcatttt cttagtaagg
    30301 aatttgctaa taaaggtgtt gatggtagac tatttgggat gtatccattt gttagttatg
    30361 ttgataagga aattcttgat aagtgtagag atttttataa cttaaaaaat ccaaatgttt
    30421 tatatccaga taaaccagga tatgcaaaca aaaacgaatt tatattattt aatgattatg
    30481 ttaattatca acaatcacaa agagaagtta tacccaatat tattaatggg aaaataagta
    30541 ttgaagatgg atttaaagaa ataaaagata gatattctca aactataaag aatatttcta
    30601 aatagccttt aaaatcgatt taaataggtc tttttagcaa tataaaatat atgatataat
    30661 aaaaagatag aaatgtattc gcagcacact tctatatctg taactaagca ttctcatgtc
    30721 ggggagtgct tttttcattt ctccaaacaa ccttgttttt ttcatcaata attattaaat
    30781 caatctcatt atcttttaaa atctctgttg cagtacaaat gagattatct aagtcaaaac
    30841 ttcgagttat ttctagttgc ttgttattta ctactctttt tagtatataa gtcttaaaac
    30901 acatttatat cacctcttgt atttactctt ttttctctaa aaatatattg ataagtaaat
    30961 atgcaacaaa taaaaaaatc tcaatgatgc atagtgttat agctataact agaagtgatt
    31021 gatttttcca tgcactataa gctatgatga aaagaaatgt aaaggtacat aatgtataat
    31081 tcataatttt aactaatata tgacttgttt tcattgttaa atataagtct ctttcatctg
    31141 cattatcgtg caattcttca acaatgcctt ttcttgaaaa agcattgtag aaattaaaga
    31201 ttgctattgt aattaaaagg aatgatgaaa ttaggaatct ttgttctttt aaaatgcagt
    31261 aaataactat actagcacaa cataacatag aagctataat acctactata aaacctcgtc
    31321 tattctttac tttcatgttt tttgtcctcc atttctttat tttcttttaa acaacatagt
    31381 tcttcaaccg ttgtatcaaa tacttgtgct atacggtagg caagcataag agaaggacta
    31441 tattgctctt tttcaataga aataattgtt ctatttgata catggactaa atcagcaagt
    31501 tgttgctgtg ttagacccat atttgttcga agttctcgta cttttgtttt cattccatgc
    31561 cctctttcta tatgaagctg acttcatgtg aagttaactt cataataact cgaaataaat
    31621 aaaatgtcaa tctcattaag aaagtattct aaactcaaaa aaataatatt ggtaaaaatt
    31681 ggatgggtat atttacctta attatcttgt ttgtaaaact ttattgagat agaatttaca
    31741 tatacataaa tcggcaaagg ggtgtaaact atgaaaatta gtaaattacc agatgcagaa
    31801 ttaaaaatta tgaaatacat atggaatact ggttataaaa ctgtaatatc aaaagatgtt
    31861 gcagatgaaa tagaaaaaac atatggttgg aagcatacaa ctacaattac acttttagct
    31921 agattaacca aaaaaggttt tttaatatcg cagagaattg ggaaacatgt acactataca
    31981 gtattggtaa aagaaagaga atatctaaaa ttagaaggta aaagaatttt tggaggttta
    32041 cataacaatc ccttgtcaga actgatttca aaattacatg atggagaaga aataactgaa
    32101 gaaaaaataa tagaaatagg gaattggata aaaagctgga aagatgaaga ttaataaata
    32161 aaaggtagct actaatataa gtgctacctt ttttgtggat aacattgggg ataagctgtg
    32221 gaaaacttat gtaaaatttg tggataaaat attttactga catttaactg acgaaagtta
    32281 aaagaataaa tagtatcaac attataaaat attgaaaaat agccatatat aaaaaataaa
    32341 ataaataaaa gtaacacttt atatatgtta ttcttttttt ttattaacaa aaaatggtta
    32401 aattgttgac ggagaggtaa aactctatta tcataataag tggatatcca atatttaact
    32461 aagtattcaa tgtgcaagaa tgcttaattt aaaaaagtta tggagggtaa atattatgaa
    32521 gaaaaaaata ggtttagtgc ccaaactaat catcggtatc atagtcggta ttttaatcgg
    32581 aagttatgca ccagaaataa tagtacaaat attagtaaca gttagtacct tattctcagc
    32641 attcctaaaa tttgttatac catttataat tataggtttt gtaacagcag gtatagctga
    32701 tttagcaaca ggtgcaggaa agttattggg gataactacg ggaatagcat atggttctac
    32761 cttaatagca ggattattat catttgcagt atctacatta atcttcccaa attttattga
    32821 tgcaagtgtt gcaagtcaaa ttggagaccc agaggcagga atgttagctc caatattcac
    32881 aattccatta gagcctatgg tagatgtaac agctgcaatc gtatttgcat ttgtaatggg
    32941 acttggaata tcagctttaa gaaatcatgg aaaaggagag actttattta atttcttcca
    33001 agaatttcaa ggaatcgtaa cgaaaacgtt gtcaacagtg attatacctt tattaccttt
    33061 atacatagca ggaacttttg caaatataac tatagcaggg gaagtatgga caatattagg
    33121 ggtattctgg aaagtatact tagtagtaat acctttacat tttgtatata tggcatgtca
    33181 attcacagca gcaggtgtat tttcaggaaa aaatccagta agaatgttaa aaaatcaagt
    33241 acctggatat ttaacagcta taggaactca atcttcagca gcaactatac cagttaatgt
    33301 tggttgtgca gaaaaaaatg gagtaagtaa gcaaataaga gaatttgttg tacctctttg
    33361 tgcaacaata catttatcag gtagtatgat atcaataaca ggatttacaa ctgcagtttt
    33421 aatgatgaat ggtatgccac atggaatagg tgtattattc ccttatattg caatgttagg
    33481 tatagcaatg gttgcagcac caggagcacc aggtggggct ataatgagtg cacttccttt
    33541 cctaccaatg gttggaatac catcagatgg tggacttgta agtttaatga tagctttata
    33601 cttaacacaa gatagttttg gtacagcatg taatgtatca ggagataatg caatagcagt
    33661 ggtagtagat aaaataaatg atggaattag taaaaaagga aacaaagaag agcaaagtgc
    33721 ttagtctttt aataatcaaa aatgagttat ctcaaataga gatagctcat tttttatggt
    33781 ataaaaaatt ataaaataaa gtgatttttt ttatttaaaa attgctttaa gagatgatat
    33841 taataattta ttttcattag gttttaatat acatactcta aagaaatact catctagacc
    33901 ttcaaatgaa caacaatctc ttattattat tttttgtgga agcagttgct ctcgaagaga
    33961 tttagcagtc aattcctttg tcttgatttt acacaatatg aaattacctt tagtattgta
    34021 tatatctaag ctttttatat tcttaagttc tttaagcagg taatctcttt cagtgttcat
    34081 taaggaaata gtatttgata taaaatctaa atcactaaac atgatttccc ccattttaga
    34141 agctattatg tttatattcc ataaatctag atttttattt atttcatttt tgacattagt
    34201 gttagatata aggccatatc caagccttat tccaggcgtt gaaaaaaatt ttgatgtacc
    34261 tcttataacg aataaattag aataatcatc aactaattga gtacaagagt atgtatctgt
    34321 atcagtaaac tctacataag tctcatcaat cattaaaaat gagtctgtat tttttaaaat
    34381 ttctctcact tctactttag taaatgcaaa tccagttgga ttactaggat tacagattac
    34441 taccaaatca taatctttag cattgatagt ttttataaga ttttctaaat ttatatgaaa
    34501 attatcttct tcttttgcaa agtatttttc tatagaacaa ttaattttag ataactcttt
    34561 ttcatactct gaataggctg gagagagtaa aagagcctgt ttaggattaa ttgtatgtat
    34621 aaatgatgaa attagttctg tagctccact gccaagtact atattatcta tagaacattt
    34681 gcagtaattg gatatagaag tttttaagtc tatgtaatca gggtcaggat acatagatac
    34741 catatctata ttgtttacaa tgtattgttt ggctaaactt gatgtaccaa aaggatttat
    34801 atttgagcta aaatccataa attcttcctt tgaaaagcca tacttactag ataaactata
    34861 taaattagct ccatggtttg tgctcataaa agtacctcca aaaataaaat tatataatcg
    34921 ataaaaataa ctgattaata tatgtacata tagattataa tacaaaggaa tcgttattcc
    34981 aaatttttaa tggaaaaagc aaaaaagtat ggataagctg ttaatttagg tttaaaaatg
    35041 atgaaaaaga ttttaattga tattttggta tgctataata tataagttaa tagaaggaaa
    35101 gcgggaggat acaaaatgta caaagttaca ggaaaaatgt tgacagaaga acaaataaaa
    35161 gaaaaagttt atgaattagg aaaaaagata gaagaagact ttaaaggcga agatttacta
    35221 gtggtaggta tacttaaagg agctagtgta tttgtttcag atttaataag atgtatagat
    35281 ttggatgtaa atatagattt tatgagtgtt acaagttatg gaaactcaac agagtcttct
    35341 ggaacagtta aaatattaaa agatttagat gtagatattg aaggaaagaa tgtgttgatt
    35401 gtagaggata taatagattc tggtttaaca ttaagtaatc tagttgcagc tttaaaaact
    35461 agaaatccaa aatctttaaa actatgtact ctacttgaca aacctcaaag aagaaaagct
    35521 aatatacctg tagactatgt tggatttgtt atagaagaca agtttattgt tggttatgga
    35581 atagattatg ctgaaaagta tagaaattta ccttatatag gtatagttga ggatgtagaa
    35641 tagatttaaa tgtgaatcaa aagcactaat ttctaaggga gttagtgctt tttagttaat
    35701 tatataaaat tttagtaaag gggacatcta tatggatatt cagttaaata tattattatt
    35761 tttccaaaat ttaagaaatc caattttgaa ctttatattt cttgtcttta caataagcac
    35821 agaagcaccg ttattaatat taattacaac aattatatac tggtgtataa ataaaaaatg
    35881 tggacagaaa atactgtttg ctataattgg aaattttgtt gtaaatttag gcatcaaaga
    35941 gtttgtaaaa gctcccagac caataggaat aaaaggtctt gaatcattga gagtttctac
    36001 tgctggtggt tattcttttc caagtgctca tactcaaact gcaacaacat tttgggttag
    36061 tattatgact atatttaaaa agagatatct tcatttaata ggtgcagtta tggttttagg
    36121 agtaggattg tctaggctgt atttagctgt tcattggcca atagatgtga tagcgggttg
    36181 gatattagga atatttttta cagttatatt tgtaaaaata tttgactata ttgatgataa
    36241 taaaaattat attttacttg tagttttact tataccattt ataatagtgg ctatatttct
    36301 aaatagccct gaatattttg aaaaatttgg tataatagta ggatttgtat ttggatatat
    36361 ggttgaggat agatttgtta aatttaatac agataataat aacaaaaaaa taaattttag
    36421 caataaaaat aaggggagta aaaatataat tttttcaaga atatgtaggt ttttggttgg
    36481 gatagtaaca ataggaatgt tatatattgg cattaagttg tttatttcaa tgttaatagt
    36541 cactttaaat ataagtgact ctactatgag tataattttt atgaatttta ttaagaatac
    36601 agtagttgtt ttttatggaa tagcaggagc tccagcatta tttaaacttt taaaattaaa
    36661 ttgattttaa ggtatagagt caatagttta aattaaaaaa attaagggta gaaaagagtg
    36721 attatttgaa gaaggtagta ataataggtg gtggaccagc agggatgata gccgcatcaa
    36781 ctgcatgtga gaaaggctat gatgtaacat taattgagaa aaatcataaa ttaggaaaaa
    36841 aacttgcaat aacaggaaaa ggtagatgta atattactaa cgcttgtgaa atagaggaat
    36901 taatagaaaa tgtacctaca aatggaaaat ttctttatag tgctttttat acttttacaa
    36961 atgatgatgt aataagtatg tttaataatc ttggagtaaa gactaaaaca gaaagaggaa
    37021 aaagggtttt tccagagagt gataaagcct ttgatattgt aaatgctctt gaaagacaac
    37081 ttaaaagtaa gaaagtaaat atattattaa attcaaaagt agaaaaaata atatctaaaa
    37141 ataataaaat tgagaaagta attttaaacg ataaaaaaga aattaagtgt gattcagttg
    37201 tagtagcaac tggtggatta agttatccac ttactggttc tactggtgat ggatataaat
    37261 ttgcaatttc acaggggcac acaattatag atacaaaacc atctttaatt ggtatagaag
    37321 taaaagaaag ttttacaaaa gatttagaaa aattatcatt gagaaatgtt gaaataaggg
    37381 tgtttaatag caaacaaaag aaagtttata gtgattttgg agaacttgaa tttactagat
    37441 ttggtttaga tggacctata atcaagtctg caagttgtag aatgaaagat acaaggaaag
    37501 aaaattacac tatattatta gatttaaaac ctgcattaga tgagaaaaaa ttggataaaa
    37561 gagttcaaaa agattttcag aagtatacaa ataaaaaatt tgaaaaagca ttagatgatt
    37621 tacttccaaa aaaactaata cctgtaataa taaacttaag tgaaattaat gcaaatacgg
    37681 ttgttcacca aatttctaga gagcagagaa aaaacttagt ccatttatta aaaaatttaa
    37741 agtttacagt aaagagatac agacctattg aagaagctat aataacttct ggtggtgtaa
    37801 aagtaaacga aataaattca agcacaatgg aatcaaaatt agtagaaggt ttattttttg
    37861 ctggagaagt aatagatata gatgcatata caggtggatt caatttgcaa atagcttttt
    37921 ctactggata tttggcaggt tttaattgct aaaaattacc tgaattaaaa atgtttaaaa
    37981 tcacataata ttatcagcaa cacaaaataa attaaacaga aggaaggtaa tcaacatggc
    38041 aagtaacaat aacaacaaca gaacagtagt accaggagca aaagaggctt taaaccaaat
    38101 gaaattagaa atagctaatg aacttggtat gagtaattat caacaagttg ataaaggaaa
    38161 ccttactgca agagaaaatg gttatgtagg tggatacatg actaaaaaat tagttgaaat
    38221 ggctgaacaa caaatggctg gaaaaagcaa cagatagtta taaataatta tttataacta
    38281 ttggctatta gtttagctag agctatctca aatatagaaa gtaatttcta aattgagata
    38341 gctttttttt attaaattat taaatagata tatttttatg taataaattt tatgtatttg
    38401 gataaaataa tacaaatgaa tatgttacat aaggagtgat gtaaaatgag tagtgtaaat
    38461 tttgaggatt taaaaaacaa atttattaat agtgacttag atgaaaaaat aagaatatat
    38521 acaacaacag aaggtttatc agtagaacaa tttaaagagc tactaaaata ttatccaata
    38581 caacatttat ctaaactaga aaaagcactt ggatagcagt atttagtcca aaattaaaaa
    38641 ggcaatttat ttaatattaa aaatattttt tattaaataa attgcctttt tataataggt
    38701 ttaaattatt atgcttttga tatataatta tagattctct catttccaag ttcaatagac
    38761 ccagtattaa taagagtaac gattccttct atatctctag cagttaagta tttatatgga
    38821 attaataaat tataaccagt attacttagt aagtttttta attgggttat ttgagagata
    38881 ttgaaacatt ttgcagtttt agtagatttt tttcttaagt tagataaatt ttcattttga
    38941 atatttatta aagtttctat atagtttcta taagatatct taaaatttgt ttcattgact
    39001 attttttcat taagtatact actgataaaa tgttgagaca atatattatc tgcaaattta
    39061 tctgctgtta attttccaga tgttatgcct ttttgatatt ttctaagaat ttttttagta
    39121 tagcagtata ttttatttct cgtttctaaa tcgagttgtt ctatttgcac aaaaccactt
    39181 ccttctaatt ataaaaatat ttattaaaaa tctatactta actaataaag cttcaataat
    39241 ttatttacag taaatactaa atcataaaat atttgttatt ttttattatt accaagtata
    39301 aaaaatatta taattgtaaa acttacaaat atatgtaaaa tatttaggag tgatgaaaat
    39361 gttaaatggg ataataaagc ttttttattc tgaaattgta aaaacaaaga ttaataacct
    39421 agactcaagt ggatattctt taagagatga atgtaaagaa atcagaaata taactctaaa
    39481 gatagatagc gtatttttta agcttttaaa gttggctttt ggttcaatac tgcttatgat
    39541 agcttttaat ttaaacatga ttctaggtat aggagtgttt ttaattggtg tagtttatat
    39601 actatataaa agaaatatgg aagaacaagt aaaagagcat ataaataatg tgaaaaataa
    39661 tatcgacatc tctaaaataa cttttatgga tgaaaaaggg agaacaggtc taaatgcatt
    39721 aattacatta cttcttatag gattattgac aggatttaac tggatattag ttgctagttt
    39781 tgtcgttgtt tttgttttta ctataaagaa tgtatgttaa aatactaata aatagtttaa
    39841 tatatagggg gagaaattga gtatgactaa tggcagttat aaaatgaaga atttagtgga
    39901 gatatccgct atggtgacgg aatctacaga tttttttaat ataaaagatg acataataga
    39961 aaaaatgtta gaagttgttc accctacaaa ggcatgtgta aatctatttt ataaaaatga
    40021 ttctaaatat gcctacttag tatgttcgca aaccttagaa tatgtacctc aaatttttcc
    40081 aataaatagt cttaaaggtg caaaaattga ttttgacaca tatccagagt atatacatga
    40141 ggctgtaaat gaaaaaaaga taatatatgt ggaaaatgta tttgaagatt ctagagcaga
    40201 aggtgaacga gatttagcaa aagctgaagg ttatattggg agaatagttt ttccttttat
    40261 aataaataat gtagttgttg gatttatgac ttgtttttta aaagaggatg attatataac
    40321 agaacaagat atagatttta tatcatctgt tgcatcactc ttaagtttat caatagaaat
    40381 aactaataaa aataataatg tacaaatttt aattgataaa ctaagaggct caataagtgc
    40441 cataaatgaa gctactaaaa aactatacct taataagagt attgatggct ttttggaaaa
    40501 tttaagtaaa caagcgtgta atattactaa tagtaaagaa gctttaataa ttataaatag
    40561 tcatcataat aaggatacta tagttagttg ttataatgtt gagcaaaaaa agaaaacaaa
    40621 tttatatcct atgattgata tgtttttaaa gaaagagtca ttagggggat acctaaataa
    40681 tttaaaacca tgctcaaaaa agggcataaa tttggaaagt tatatatatt acaaacttca
    40741 ggataaaaat gagactatag gatgtatagt ttgtgcaaat agtaaaaact atactagtga
    40801 tgatttaaat attcttagta tattgtccaa acaagtttct gttgggatgc aattatatga
    40861 acataatgaa aaggaagtaa aacacaaagt tcttgaaaat gagttgaaca tattaaataa
    40921 acaacaacag cttattatgg ataaaggtaa aatggattgt aatgatgaga aagaacttta
    40981 tttttaccat aaaccatcaa gggtagtagg tggagatttt tattatgcta caaaagtgga
    41041 tgacgaacat atagtttata ttgttgctga tgtaatggga catggaatgg tatcaaatta
    41101 tgttgttgca atgataaaag gtgcttttaa agtattatgc aatcaataca atacaccaag
    41161 agaaataatg acaaatttaa ataggatgtt atatgatgaa tttgacaaga tgggagtatt
    41221 tacaacttgt ttgataggta ttatagatac taaagaaaat atgattactg tgtctaatgc
    41281 aggtcactat agtcctgtag ttgtaaagaa agatggcaca atagaaaata atttaaattg
    41341 taaaaagggc atacctattg gaataatgga agatgctact tatgaaaata atactctttc
    41401 aatggaagat tatgcaatgg tatgtatgta cactgatgga attttagaga taaaaaattc
    41461 atcaaaagaa gagtatggta taaacagatt agaaaacttt ctaaaagaaa attttagatt
    41521 aaatcaacag ttaatagtag aaaatctaaa attggattta aagaatttct catcaaaaga
    41581 taattatgat gatgatattt taatagttat gttaaaggat aggtagattg attatggatt
    41641 caaacgataa aaaaggactt aaaagtccag agattataat aataaatgga agtccaagaa
    41701 ttaataaaaa ttgcagtttt atagcaaata aagtaaaagc tatgctagaa gagtgtgggt
    41761 taagttgtaa aatatttaat atctacaata tggatattga atattgcaca gcatgtggat
    41821 tttgtgaaaa aacagggtat tgcaagttta atgatgatat gaagccatta tataaaatgt
    41881 ttgatgattc aaaaggaact atagtaataa gtcctgtaca ttttgattca atatcagcta
    41941 aattaaagac tgttgttgat agaactcaag ctatatatgc aagtaaatat gtattaaata
    42001 aaccttcaat tgatagaaat aagaaacgga taggaatgta tattgcagtg ggggggagta
    42061 aatcatatga ttcacagttt aaaggtggac agattgttat ggattttttc tttaagagta
    42121 taaatactaa acttttacac aatatatatt taaacaatac agatgatgta tcttatatag
    42181 ataatcaaga atttaaagat ataatatata aaaatttaaa gatatatatt gattcaatat
    42241 aatttgattt tgtaggtaat attatgtata attgtattgc aataatttaa ataattaaaa
    42301 ggagggaatt tcaatgaaat taccaatagc attatctaat aaacatgttc atttgagtca
    42361 agctgatata gacgtattat ttggggcggg tcatgagtta actaaattta aaccattatc
    42421 tcaaccaggg caatatgcct gtgaagaaaa agtggattta gtaggaccaa aaggaacttt
    42481 aaaaggagtt agagtactag gaccagctag agctcatact caagttgaaa tatctttagc
    42541 agatggtttc ccattaggag taaaagcacc aataaaagaa tctggtgata tagctggaac
    42601 tccaggtgtt aaattagtag gacctgctgg agaagttgaa atgaaagaag gagttatagt
    42661 tgcttctaga catatacata tgagcaatga agatgctgct aaatttggtg taactgataa
    42721 gcaaatagta aaagttaaaa catctggacc aagagcatta gtatttgaaa atgtattagt
    42781 aagagctagt gatagcttta atctagaaat gcatgttgat atggaagagg gaaatgcagc
    42841 aggcgttaaa aatggagatt tagtagaatt aatagttgat taatattata aatagacttt
    42901 atgctagtag atattttatt tgctagcata tttttaaatg taataaattt ctataggata
    42961 aatttaatcg attagattaa tttataaaat aaaggggtat tataaaaaat gtaataaaaa
    43021 cttacaaaaa tatgatgtaa tatggtaaaa ttatatatat aaaaatttac atataataaa
    43081 gataattatt ttactttttg tactaatata aacaaataga taaaaaagtt tgaaaagtct
    43141 aacttaattt attatatatt gtatacaaaa ttatgaaaaa aacttaacat atttaatttt
    43201 aaaaaaaatc tacttaaata tgtaattaat ttacaatttt caaaggaatt ttatctaatc
    43261 tgtagtatta tattagaaga tagagtattt gcgcgactat atgtgtgttt atatttttgt
    43321 tgtgtaaatt atatgtaaat ataaaaaaat agacttgtta taaacaagta caattgtagc
    43381 tatcaaggag gatacatatt atggctaagt ttatgaaaac acttgatgga aatacagctg
    43441 cagctcatgt tgcctatgcg tttacagatg tagcagctat atatccaatc acaccatctt
    43501 caactatggc tgaagtagtt gatgagtggg catcacaagg aagaaaaaat atatttggac
    43561 aaacagttaa tgttgttgaa atgcagtcag aagcaggtgc atcaggaaca ttccacggtt
    43621 ctttacaagg aggagcttta acttctactt ttacagcatc tcaaggttta ttattaatga
    43681 tacctaacat gtataaagtt gcaggagagt tattaccagg agtattccat gtaagtgctc
    43741 gtgctttggc atctcaagcg ttatcaatat ttggggatca ccaagacgtt atggctgcta
    43801 gacaaactgg atgtgtatta ttagcttctg gttcagttca agaagtagct gatatagcac
    43861 ctgttgcaca tttagctgca atagaaggta gattaccatt tatacatttc tttgatggat
    43921 tcagaacttc acatgaaatc caaaaagttg aattactaga aaatgaagat tatgcaagtt
    43981 tattaaactt tgaagcagtt caagcattta gagataatgc tttatctcca aatcatccag
    44041 ttgctcgtgg tactgctcaa aacccagata tatatttcca aactagagaa gcttctaata
    44101 aatactatca aaatatagta ggtatagttg aaaaatacat ggaaaaaatg agtaatttaa
    44161 caggtagaaa acatagttta tttgattact atggagcaga agatgctaaa tacgtattaa
    44221 tagctatggg ttcagtaaca gaaacaatag aagaaactat agattactta aatgctaagg
    44281 gagaaaaata tggtttagtt aaagttcatt tatatagacc attctcaatg aaacatttct
    44341 tagatgctat gccatctact gttgaaagaa tatgtgtact tgatagaact aaagagccag
    44401 gttcaactgg tgaaccatta tacttagatg tacgtgatgt attctatgga aaagaaaatg
    44461 ctcctatgat aataggtgga agatacggat taggttcaaa agatactact ccttcagata
    44521 taaaaactgt ttttgataac ttagtttcag aacaacctaa aaatggattt acagtaggta
    44581 tagttgatga tgtaactaat acttctttaa ctccatctga gccaataaaa atagcttcta
    44641 aaggaactat aagatgtaag ttctggggat taggttctga cggtactgtt ggagctaata
    44701 aacaagctat caaaataatc ggtgaccata ctgaaaaata tgctcaagct tactttgatt
    44761 atgactctaa aaaatctggt ggtataacta tgtctcactt aagatttggt gatactccaa
    44821 taagagctac ttatttaata gatgaagctg attatattgc ctgtcataaa caatcatatg
    44881 tttatcaata tgatttatta aaaggtctta aaaaaggtgg tacatttgta cttaacacta
    44941 tatgggacca agcaggactt gaagaacatt taccagctca tatgaaacaa tatatagcta
    45001 aaaatgatat aaaattctat acagttaatg ctgttaaact aggacaagaa ataggtcttg
    45061 gaaacagaat aaacatgata atgcaatctg cattctttaa attagctgaa ataataccag
    45121 aagaagatgc tgttaaatac ttaaaagatt ctatagttaa agcttatggt aaaaaaggtg
    45181 aaaaaatagt taatatgaac tatgctgctg ttgatgcagg aataaatgct ttagttaaag
    45241 ttgaagttcc agcttcttgg gaaaatgctg ttgatgcaga taaaggagaa gttaaagaac
    45301 cagaatttat aaaaaatata ctaagaccaa tgactgcaca agaaggaaac aacttaccag
    45361 taagtacatt caatggtata gaagatggaa cattcccttg tggtactgca gcttatgaaa
    45421 aacgtggtat agctgttgat gttcctgaat ggataataga taactgtatt caatgtaacc
    45481 aatgttcttt tatatgtcct catgcatgta taagaccagt attagttact gaagaagaat
    45541 tagctaatgc tccagaagga tttgaagcta aaaaagcatt aggtaaagga ttagaaggat
    45601 taaaatatag aattcaagtt agtccacttg actgtacagg atgtggaaac tgtgctgaca
    45661 tatgtccagc taaagaaaaa gctttagtta tgaagccaat agatactcaa cttgatacag
    45721 agttagataa ttgggcattt gcagtaaatc ctgatgaagt agctccaaaa gttgatgtta
    45781 tgcctgcaaa tactgttaaa ggaagtcaat ttagacaacc attaatggag ttttcaggag
    45841 catgtgctgg atgtggagaa actgcgtaca ttaaagtagt tacacaatta tatggagata
    45901 gaatgatgat agctaatgct actggatgtt cttctatatg gggagcttct gcaccatcaa
    45961 ttccttatac ttgtaaccat gaaggtaaag gtccatcttg ggcaaattct ttattcgagg
    46021 ataatgctga atatggattt ggtatgtaca cagctgttaa gcaaataaga aataaaatag
    46081 tagatgctat gacagagtta gtttctatgg atatctgtga agatgctaaa gcagtattta
    46141 cagagtggtt agattctaga aatgatggag aagcttctaa agtagcaagt gctaaggttg
    46201 ttgaattatt agaaaaacca gcttgtgatt gtacagatga aaaagctaaa gaattagtaa
    46261 aagctataaa agatagaaaa gattatctag ttaagagatc tcaatggata ctaggtggag
    46321 acggttgggc atatgatatt ggttacggtg gattagacca tgttcttgca tctggtgaag
    46381 atgtaaacgt acttgtattt gatacagaag tatattcaaa tacaggaggt caagcttcta
    46441 aagctactcc agctgctgct atggctaagt ttgctgcttc aggtaaaaaa tctagaaaga
    46501 aagatttagg aatgatggct atgacatatg gaaacgtata tgtagctcaa gttgctatgg
    46561 gtgctgataa aaatcaattt atcaaagccg ttttagaagc tgaaaaacat gatgggccat
    46621 ctctaataat agcttatgct ccatgtataa accatggatt aaaagaaggt atgggaagaa
    46681 ctgtggctaa tgaagcacaa gctgttgctt gcggatactg gcatttatac agattcaatc
    46741 cagaagtaaa agctgaaggt aaaaacccat tcactttaga ttcaaaagaa ccaactgcaa
    46801 gcttcaaaga tttcatactt gcacaagtaa gatattctgc tatagctaaa caattcccag
    46861 aggaagctga tggattattt gctaaagctg aagctgatgc taaagaaaga tatgaaggat
    46921 acaaaaaatt agctgaataa tattaaagta ttataatgct tatatagaat tgataaaaga
    46981 gagtgtctca aagtgagctt tttagttcat gaggcactct ttttgtatga aatcaaatat
    47041 attttaatca tttcaacaat gaaaaaggtc ttatctctat tttgagacag cccttttttt
    47101 atgaagatat taagattttg tttttaccta ttaaatatct tttttaagtt ttccattttc
    47161 atcttgccaa tactttttat atattgttct acacactaaa attaagagaa caaataatat
    47221 ttatagtatg tatatttgga tttgataatt ttaaaataga tacaaaagag tatctcattt
    47281 gtgtttttta tcacttagag atactctttt gatatgtatg gaaaaagagt attttatcct
    47341 acaaagattt gtgtccaata aattgaacca ccactttttt gtgctactcc aacacctatt
    47401 ttactgaaat ttggattcat tatatttttt ctgtgacctt cagaattcat ccatgcgttt
    47461 acaacttctt taggagtttt ttgacccata gctatatttt cacctgctgt cttatagctt
    47521 attccaaatt ttttcaacat gtcaaatgga gaaccataag ttggagaatt gtgtgaaaaa
    47581 tagttgttat caatcatatc ttgagatttt tttgtagcaa catttgatat agaagaatca
    47641 agagtaagag gatttaatcc agctttagct ctttctatat ttactaagtc gacaacttct
    47701 ttttggtaag ctgaaaaatt ttcacttgta gagcctgagt tgttattatc atcaggtttg
    47761 ttagtagagt ctgaattatt gttgtcttca ggtttattag actctggttt attgttatca
    47821 ggtttatcag tagagcctga attattgttg tcttcaggtt tattagactc tggtttattg
    47881 ttatcaggtt tattagtaga gcctgaatta ttgttgtcct caggtttatt agactctggt
    47941 ttattgttat caggcttatt agtagagtct gaattattgt tgtcctcagg tttattagtg
    48001 ttgttgcaat tcttgtcatt atgattctta tccttacaag agttatcttt atcaggttta
    48061 agttctggtt ttacagaaca atttggtttt gcagaaaact tgtatttagt attactatat
    48121 actaaacttt tgttacttat atttacatta ttttcaagtg atgaagcact tgcagtaaca
    48181 gcacttgaag ctgttgctaa agttaacact cctaaagcta atatagtttt taattttgtt
    48241 ggtatatttc ttctcatcat taaacacctc ttaatctaaa aattctaaaa atgttactga
    48301 tttgtaacct ttagtgtagg gggtacccgt gaatctatac taacataaga ttaagacttt
    48361 ttttactgta aagatatgta aaaaagatat atatggaata aataggtata tttcagtgtg
    48421 tttgaaaatt tgtattaaaa gcctgtatag tatggaatta cttacttaga gaaaataata
    48481 tttttataat aattccataa cgtaaattta tagttatgat aaattttttt ttatttggtt
    48541 aaatttattc aatagatgct ttcgtattag taacaaatta taattgttta aatctttaag
    48601 gaataaaaag ggtttgtctc aaaatagaga aaggttcttt tttattgttg aaatgattaa
    48661 aatatatttg atttcataca aaaagagtgt ctcattaagt aaaaagttca ctttgagaca
    48721 ccacctttca tattatgaat tttaatttgt tttatattaa tacattagta atcctaatgt
    48781 aattacaata atttctgcta ttagtgaacc aactgcaact acaatgaaag tttctttaaa
    48841 tccagtttta tgtgttaact tagataagct taagaatgta agaaaaacac cactttgtgg
    48901 aactatagtt agtatatttg aggctattgt agcaacacgg tgaattaatt ctggatttag
    48961 accagtactt aaataataat ctgcaaagtt tggcattact attcctaatg caccagaaga
    49021 ggaccctgtt attgctgaca ttgttgaagt caaaacagta agacttataa gtggactacc
    49081 tggtattgac attataagtt tgctaaatac atcaaaacca ggtgcagcca ttattactgc
    49141 tccaaatgca actgcagaag atgtagcaaa tataggacct atagaaccac tagcacctat
    49201 gctcaatgtc tgtatcttag atgatagaaa tttatggaat aaaaaagcag ataaaagaat
    49261 tgcaactatt aaagctatgt aaattacatt ttttttcata aattctgaac caaaagtact
    49321 tccagttata gctataatta cgagtgctaa tagaggaaaa atacttgcaa aaaatcctgg
    49381 taattctcta tctaaagatt cttcttctaa ttctgaagtg taagttgcgt aagtttcacc
    49441 ttttctaata cttttgttta gagcatattt catatagaca agtccaaacg tagcacaacc
    49501 tatactacct acaatacttg gtatagtagc tgcagtaaga gacgtattta gatattgaat
    49561 aggtataaca ttttgaatgg ctggtgttcc aggaattata gtcatagtaa ttgttgcaat
    49621 accaagccaa agtggtatct gaataaggtt ccaagaaata tcaagttttt taaatagagt
    49681 tcttgcaagt ggaatgactg caaacataac tacaaataag cttataccac catacgttaa
    49741 tataaaactt actataaata tagcaactaa aactctataa ggatgattag agccaaattt
    49801 atttaaaata aaatcagcta ttgatacagt ggctccactt tcttccataa atttagcaag
    49861 tattgagcct aataagaata ttgcaaaata actcattata tagtttccaa gtgcacccat
    49921 ataattgttt ttgtcagcac ctagcattga tgttacaaca tccattttat ttaagagaac
    49981 aactattaaa gttgctattg gagcagctat agttatatga atttctttaa ctgaaaaata
    50041 tataatagct atgataccaa taattatacc aattggtgcg ataatactca taaatatccc
    50101 tccttagtag aaggacctga agaatacttt cttcaagccc taaatataat aactattgtg
    50161 cagtatatcc tccatctagt aagcaagctt gtcctgtaat acccttagca ttatcacttg
    50221 ctaggaacat agcatagtcg gcaatttctt gaacatctaa taggcgtttt tgtggtacaa
    50281 gtgggtacaa aacttcctct aagacatttt ctaatggtat attacgagtt tttgaaaggt
    50341 cattaaactg acctctgaca agtggagtat ctacatatcc agggcataaa gcattaactg
    50401 ttataccaga atcggcagct tcaagagcag caacttttgt tagtccaata agtccatgtt
    50461 ttgctgagtt ataagcagcc tttccagcaa atcctattac accattgatt gaggccatat
    50521 ttattatacg accaaagcct tgttttttca ttataggaaa tgctttttta gtagctataa
    50581 aaggtgctgt cagcattatt tttatcataa attcaaattt atcagttggg aaatcttcta
    50641 tcatagaaac atgttgaagt ccagcattgt ttattaatat atctaatctg ccatactttt
    50701 caacagtttt atctatagcg tggttaattt cttcttcctt agttacatca cactttacac
    50761 tcatgcaatc ataacctttt ttttgtaact ctgttatggt attatttaaa gcttcttgat
    50821 ttatatcaga gaacattact ttagcaccat tttttaagaa cgattcagct atttgtttac
    50881 ctattccact tgcagctcct gttacgaata caactttatc tttaaccatt ttcatttcct
    50941 ccaattttat tttattttta tattaatatt ttaagcaata caaatttata tgtaatacgt
    51001 ctaagagatt tttattttct agttttaatt attttaaaca acagatattt ttccatttaa
    51061 tgaatctgac aatattaaag gagcttcagt agcagaaata acatcatcta atgtgaaagt
    51121 tggatttatt tctttaagta aaattccatc tgatgttact tccataactc ccatttcagt
    51181 aactatcaaa tctacagcat ttgttgcagt aagtggaaga gtacaattat ttaatatttt
    51241 tgcagaacct tttgaagtat gttccattgc tacaataact tttttagctc cagttactag
    51301 gtccatagct ccacccatac ctggaaccat cttacctgga atcatatagt ttgctatatt
    51361 gccatatttg tcaacctgaa gtgctccaag aacagttata tcaacatgac ctcctctgat
    51421 tattccaaaa gaagtagcac tatcaaagaa acatcctcca ggaagtatag taactggttg
    51481 accacctgca tttacaatag tttcatcact tgaatttcca tcttcggctg aacctaaacc
    51541 taaaaagcca ttttcagatt gtaagataac gtttacatta tccggaatat aatttgctac
    51601 tttggttggt agacctattc caaggtttac aacggctccg tcttttaatt ctttagatac
    51661 tctatttgca atatattctt gcatttctaa tttatccatt ataaattacc tccttcaacg
    51721 atgtaattca caaaaatacc tggtgtatta acttcatttg ggtcaatatc accaatttca
    51781 acgatttcat ctgcttcaac tattgtaatt tcggcagcag atgccattaa attattaaaa
    51841 ttgttcatag agcctttata aactagatta cctactttat cgacctttga tgcaaataga
    51901 agagcaacat ctgcataaat tggtttttca agaaggtatt ctttgctatc gacaacaatt
    51961 ttttgctttc cctcctcaac aagagtacca ataccagtcg gtgtgagtat acctcctaga
    52021 ccataaccag ctgcacgtat ttgttcagca agagttccct gaggaactaa ctcaacatct
    52081 gtttcattgt tgttcatttg tcttccagtt tctttattta atcctacatg agaagcaatt
    52141 atctttttaa attgcttatt tacaaccatt ttgccaactc ctttgtcaat aaagccagta
    52201 tcattgcaaa ttagtgtcaa atcttttata tttttactac ataaataatc aattaaattt
    52261 tctggtgaac cattggccat gaatccacca accattattg tatctccatc ttttacatga
    52321 gatagagctt catcaatgct aactatttta ttcatatttc ctcctatcgt gaaaccacca
    52381 ttgatattcc ttgaccacca ccaatacaaa gtgttacaag tccagtttca actttacgtt
    52441 tttgcatttc ataaattagg gtaacaagta ttctagctcc acttgctcct attggatgtc
    52501 ctaatgctat tgcaccacca ttaacattta actttgatga atctatttga agttcatttt
    52561 taacagctaa tgcttgggca gcaaatgctt cgtttgcttc tattaagtct atatcattga
    52621 tgctaagtcc agcttttttc agtgcttttc tagttgcagg gattggacca gtacccatga
    52681 tttcaggttc aacaccagct gaagcatagg attttatttt agcaagtggt ctaataccta
    52741 gttcgtctgc tttttgttgg ctcattagta ttaacatagc tgcaccatca ttaatacctg
    52801 aggcatttcc agctgttaca gtgccatctt ttttgaatgc aggtttaagt ttagctaaac
    52861 cttcaaatgt catacctaat ttaggatatt catctttatc aatagtttct atttttcctc
    52921 gacgtattaa aacatctact ggaacgattt cttctttaaa gcggttgttt tttatagcat
    52981 tctcagcctt attttgactt tctaatgcca atttatcttg catttctcta gtaaattcaa
    53041 atttagttgc aatattttct gcagttattc ccatatgata ctgattgaaa gcatcaataa
    53101 ggccatctgt tagcatacta tctaccatgg ttatgtcacc cattttacta ccaaagcgag
    53161 cagttggaac gatataagga gcttggctca tattttcagt accacctgca attaccacat
    53221 cattttcacc agatgtgatt gattgggcag ctagctgaac acttttaagc cctgaaccac
    53281 ataatttatt tactgtgtag cttggaacag aatttggtat acctgaattt atagcaattt
    53341 gcctagcaac attctgtcca agccctgttt gaagaacatt tccaattatt acttcatcta
    53401 tttcagataa attaagtcct acacgtgata tcgcttcttt aacagcgata gttccaagtt
    53461 gaacagctga agtattttta aatacacctc caaaacttcc tataggtgtt ctgactgctg
    53521 atacgattac tacatctttc atatctaata gttacctttc ttgaatgata attaaaaatt
    53581 ttctgaataa agaaattagg gaacactata ataaagtact tttttaatac aagcttgttt
    53641 ttaagtattt caattacttt tattcctaat gctttaggtt ttcctgtttc taattataga
    53701 ttacggcgaa aaaagcattt tgtctaagtc taatttttta tatagtgtat aagaaaaatt
    53761 tataggataa aaatttatag tagatttaga aaaatatttt gttaaaatat taatgaaatt
    53821 atgttgattt tcctataaaa tatcattaga agaaaaaata taatctaaat tatacttttg
    53881 gggaaggggg tttaaaatgg atataaaaca gttgaaatat tttgttgaaa tagtgaaatc
    53941 tggttttaat ttatcaatag catctaagac acttcacata tctcaaccag cattaagtca
    54001 aattataaaa aattttgaag aaagtgaaga tgtatattta tttgaaaggt ataaaggtag
    54061 gttaaatggg ttaacaccag caggagaaag attttatgta aatgcagaac atattataaa
    54121 tgaatacaaa aatatgatgg aagatttaag agaagattca gttcaattta aaggaaaagt
    54181 tagaatagga atacctccac ttatacttgg aatagcattt tcagatgtag ttgcacagtt
    54241 agttgcaaat aatccagata tagaatttga tatagtagag aagggtgcat atgacttaaa
    54301 tagaatgctt atcttgcagg aactagatta tgcagtactg ttacatccac ataaaattga
    54361 taaaagtgta gtaactgaac atgtgcttca agaagatgaa cttacagcat ttttaaatat
    54421 aaatcatcca cttgctaaga aggataagat agattggaac gatttgaatg agcaattact
    54481 tgcaatattt aatcctactt ttatgataca tcataagcta atgcaaaaat ttactgatga
    54541 aaatgttaag ttaaaaagat atataatgtc tggttcatgg gattttttgt tgctatcaac
    54601 cacaaattct gattttataa caattttacc atcaccagtt catgattttt ttgaaaatag
    54661 caaaattata gaaaagcctt ttaatcatcc tattacatgg aaagttatac tatgtagacc
    54721 taaaaaagaa cgttatagcc atgtagacca acatgtattt aaatttatta tagatttctt
    54781 tagtaaaaag aactcttaaa aatgttatta aaataacaaa taaataaatc aatttttatt
    54841 acaataaact attagttttt catctatatg tttgagagca ataataggct ttacataaca
    54901 tggtagagta gtatttaaag ttataatata caaaatatgt attttttaaa cgaaaagtaa
    54961 aaacagtgta tatctttaga taatcactgt ttttattttc tatataaaat ttgttaagta
    55021 ttactagaaa attttttgct tattatagtc aaactcatga ctgttaaaaa tataagtaat
    55081 cctggaaata cagctaaata taacttgtca aaaatatgtc tttgagcatc ttgaagcata
    55141 ttaccccatg atgcaagagg taattggatt ccaagaccta aaaaactaag agcggattca
    55201 gttaagatag cattagcaat atttaacgaa ccagcgacta caatagtctc ttttaagttt
    55261 aaaactatat gtcttaatag tatatttcta gtcttgatac cagtagcttt agcagctaga
    55321 cagtattcat tttcctttat ttttaatgtt tcgccacgta caattcttga aacttccatc
    55381 caacttaaga atccaataat tagtataata gtggaaactt taggtgttag ataagtattt
    55441 aatacaatca aaactaagaa acttggtata ctcataagca tatctactaa tctcatcaag
    55501 aattggtcta gcttacctcc aatatatcca ctaataacac ctacagcagt accaaatact
    55561 acagagataa gcattgataa aataccaaca ctaagtgaaa tccttccacc ataaagagct
    55621 ctagagaagt aatctctacc aagttcgtct gtaccaaaga tatgctttaa gctaggttct
    55681 tgaagtttag aagtagtatc aattgcatta gagtctatat ttaatataaa agaagctata
    55741 attaatatga ttattatgct aagagtaata catgcaaaag caaaggattt atcttttttt
    55801 aattttttta agatacttgt aaacacaact agaatcctcc tttgctagat tttattttag
    55861 gatcaattaa taagtatagt atatcagcaa ctaaattacc taaaattaaa aatagtgctg
    55921 ataacatagt tattgccata attacagtat aatctcttga aaaaattgaa tcaatcatta
    55981 atcttcccat acctggccaa gagaaaacta cttctgtaac aaatgcacca gtgactaatt
    56041 tttgtatact catgcctagg attgtaacca atgatgtcag tgaatttttc aagacatgtt
    56101 taaatagtat gactttttct gataatcctt ttgctcttgc tgtaataaca tattgttttt
    56161 ttaattgttc atttacacta gcttctacat aatttgtaaa aatagcagta ttatatagac
    56221 ctaaagttat tacaggcaaa actaaatgtt ttactaaatc tccaatacta tcatttccaa
    56281 tagtatgcat acctcctgat gggaaaatgt taagtttaac tgaaaaaatt gaaatgagta
    56341 tcatacctat ccaaaaagaa gggatagaaa cacctatata attaaaaaca gatgatactt
    56401 tactagttat tgaattttta tttacagcta aaaatattcc aagaggtata gctaccaata
    56461 ttgaaaatat caaagaagta cccataagaa taaatgtatt tcccattttt tccataattt
    56521 gttctgtaac gggcatatgg tttatataag aaatacctaa gtttccactt aaagtgtttt
    56581 tcaaccagtt taaatatctt atatatactg gtttatcaag ccccatattg acccttatat
    56641 tttcaatatc ctgtgaagac attaaaggat ttatatatgc atctgctggg tcaccaggag
    56701 ctaattctaa aagtccaaat gataatatag atattaagat taacataggt attaaaactt
    56761 ttactctatt caatattaat tttaacataa gtaaattctc ctaattaaaa gagatgtctc
    56821 gttttaaaat aataaaacaa tattattttt agacatctcc ttttctaatt aataatataa
    56881 aattttacat caattattct acatacagtt tagaccaatc ttcaaataat attgcaggag
    56941 atggtttagc atcttttatt ccttttagat ttttttgagc tgccattaaa ttttgttcat
    57001 aatctatagt gtaaataggt gcatccttag atatatcctg ttgtatttgc ttatatattt
    57061 cttcacgttt ttccttgttt aactcagtaa atcctttttc ccataaagca tctatttcag
    57121 cattagaata tttagtttgg ttgcaatatt gaccagtttc aaacatacct ctatatgggt
    57181 ttggttctaa tccccaagca taaccattta catacatatc acattcagtg ctattactaa
    57241 atagtatatt aaagaatgcc ttactttcat aaggaactat ttcagcttct ataccaattt
    57301 ttttcaactc ttgttgagct actaaggcat agtttttatg cccaaatcta cctgtgttat
    57361 aacctatttt taatttatca attttaacac cacttttatc caataagtct ttagccttat
    57421 ttgtatcttg gtcatatcct tcaacacctt cttctgtata gaagtctgct tctggaacta
    57481 atatagattt agcaggtaca gaaccttctt ttccatatgc tgattctatc atttcatttc
    57541 tatttaaggc atatgataag gcttgtctta cttctttgtt agccatgttt gatatatttt
    57601 ggttaaatac aatgtagttt aatctttctt cactataagt ataagtttgt aagtttgatt
    57661 ttgattttgc cttttcatat ccttcagcag atgtcttcat aagtgaaatt tcgccattat
    57721 ttaaagctgc ttcttgagat gcttcattag gaattatttt tagcgctata gaatctgcct
    57781 taggttctcc accaaaataa tctgcattct tttcaaatac tatgctttca ccttttttcc
    57841 attccttaaa cttgaatgca ccagaaccaa ctggattatt atttttttct gacttagcta
    57901 tatttgattc tccttcaaat acatgttttg gtattggaga aattttagat ataccatata
    57961 agaaagattc acttgcagtt ggtaaagtaa tcttaactgt taaatcatca attttttcta
    58021 ctttaactgg tttttcaccc accaataagt attgtcttga tggtgaattt tgtttttcgt
    58081 ctaaaactgt attaaatgta aataagacat cttcagcagt tattggtttt ccatcatgcc
    58141 attttaaatt ggattttaat tttatagtta attccttact atctttaaaa tctacttttt
    58201 ctgctaaata atttactaaa ttcccttttt cataagtata aagaggagca taaactatat
    58261 ttgatgcaag agagtcttct ttaacgtttg caaaagctcc attgattata tctgggtcac
    58321 ttgccatagg tattacaaca gttccaccag atttgcttcc actagacttg tctttatcat
    58381 tggaagcaca ggctgtaaat gtaagcatta atgatgaaac taagattaat gatgccaatt
    58441 ttttaaattt catattctta taaaacctcc ataaaataat atttaacaca tatttttcat
    58501 tgtataatag taatcattat taaa
//
LOCUS       DACTZW010000013        58491 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.013, whole genome shotgun sequence.
ACCESSION   DACTZW010000013 DACTZW010000000
VERSION     DACTZW010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 58491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58491
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.013"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            69..142
                     /locus_tag="JAM15_04470"
     tRNA            69..142
                     /locus_tag="JAM15_04470"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:101..103,aa:Gly,seq:tcc)
     gene            151..267
                     /gene="rrf"
                     /locus_tag="JAM15_04475"
     rRNA            151..267
                     /gene="rrf"
                     /locus_tag="JAM15_04475"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            541..2559
                     /locus_tag="JAM15_04480"
     CDS             541..2559
                     /locus_tag="JAM15_04480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAT6797517.1"
                     /translation="MRRNTKLLTTGILSMAIVAPTMAFATESNAMENNADLNINLEKK
                     SIVLGSKSKVSVKFKEKPDADSITLKYKCYDMPLDTTLNYNQSTESYEGTINYNKDPE
                     YLNVWELQGITINSKNNPKTLNKQDLEKMGLNLKDYNVTQECIIEDITSRKDVNKYLR
                     KTSAPITELTGSDRYETAVKISQEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPI
                     LLIEKNNVPNSVKSELKRLNPKDVIIIGDENAISKTTANQIKSTVNASQTRLKGSNRY
                     ETSLLIAKEIDKNHDVEKVYITNANGGEVDALTIAAKAGQDKQPIILTDKDSITDNTY
                     KWLKSEDLQNAYFIGGPQMISTNVINKVNDITKDNVTNNRVYGADRHETNANVIKKFY
                     TDDELEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKENLEAKSANKVY
                     KIGGGLTSKVMNSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSDTGTTGKPLGGIK
                     EKDYTLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLRPDLFTSIHYNAS
                     DTTGNGVEVFYKLKDKDGGTTKTVATNILNRILEKFNLKNRGAKTRTLSTDPTKDYLY
                     VLRNNDMPAVLVECAFLDNEKDMSLLNTSNKVKEMGTQIGKGIEDSLK"
     gene            3053..5065
                     /locus_tag="JAM15_04485"
     CDS             3053..5065
                     /locus_tag="JAM15_04485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAT6797518.1"
                     /translation="MRRNTKLLTTGILSMAIVAPTMAFATESNAMENNADLNINLEKK
                     SIVLGSKSKVSVKFKEKPDADSITLKYKCYDMPLDTTLNYNQSTGAYEGTINYNQDPE
                     YLNVWELQGITINSKNNPKTLNKQDLEKMGLNLKDYNVTQECIIEDITSRKDVNKYLR
                     KTSSPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPI
                     LLVEKNNVPDNVKSELKRLNPKDVIIIGDENAISKTTANQIKSTVNASQTRLNGSNIY
                     ETSLLIAKEIDKNHDVEKVYITNANGGEVDALTIAAKAGQDKQPIILTDKDSITDNTY
                     KWLKSEDLQNAYFIGGPQMISTNVINKVNGITKDSVTNNRVYGEDRHETNANVIKKFY
                     TDDELEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKENLEAKSANKVY
                     KIGGGLTSKVMSSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSAPGNSSGGMIEKD
                     YNLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLKPDLFTSIHYNGSTNK
                     QGHGVEVFYKLKDKNGGTTKTVATNILNRILEKFKLTNRGIKTRVLPSDSTKDYLYVL
                     RSNDMPAVLVECAFLDNENDMSLINSSAKVKEMGTQIGKGIEDSLK"
     gene            5307..7220
                     /locus_tag="JAM15_04490"
     CDS             5307..7220
                     /locus_tag="JAM15_04490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797519.1"
                     /translation="MEYLFEKSSLKEYGNEALDKYRELLDKTGNNSRCILLLVPNNNT
                     KIRYERALRLNYSEELKITTYISFVKKELVKYWPLIIEKCDEINTKVVSPTFISNSLS
                     EYLIVQKVKEKRIQEGYFEDITGTNKSIANSIMTNINKSAFNLIDFDFIGEKIYSSKK
                     NKDSIYRFSYTQMDEIISYYINSLLSNSILDNALSIYLYNQYLLNDDFYLKNLFTEVR
                     YIIVDSLESSSNAEVDFITEALDNTLQSYIYFDYSRDYSVFNNVDIDYINEKIISKIK
                     PKEENIKKKEIRIEDLYLLPANIELNQSSQLYNEMLDLISEKVISLIEEDVSPRDIAI
                     ISPINNSILEHQIRDSLIEKNIDVFSTKKDKKAVDYPYGNALVVATCIFYGYLDFIKD
                     DEYLSFLETLLEINRIKAFKIFNETRHLSIDNIDEHSQYRDILQYIEEKKKSDIKIHE
                     FLTQFYIDKMLNLKEGKKNVGLCKKIIAESESFSESLSLLRMKKEKIFIEALKSTIND
                     YYSVVDIEELKSKDKIVITTPYSYISSNIDRSIQIWVDIGSNAWNMKIEKDISNLIVL
                     RKSFEEKKIYTNEMEEYYKKYYLYNTVYNLLLNAKKIYAFKSEYAINGYIQESILYSI
                     LLKISHKGDKNYD"
     gene            7213..9432
                     /locus_tag="JAM15_04495"
     CDS             7213..9432
                     /locus_tag="JAM15_04495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAT6797520.1"
                     /translation="MININYREDQIPIINYDNGTMAVPAVPGAGKTFIITNLVAKLLL
                     EQKHKGGKILILTYMNSAVNNFKGRIRKILEENKIDDTNSYEVMTIHSLAVKIIKEKP
                     EVVMLSEDFNIADDLQKSIILNECISRFRFEGGERAFRWFLKEQKDERWKEITLEAWE
                     RGFFEFAGNAISELKYKGISPDKLEEILSRGHKGMLKIILPIYKLYDRKLKQNGLLDY
                     DDILILAEKTLSLDEGLRKKFQTRYKYIFEDECQDSNEIQGNIIKIISSENKNLVRVG
                     DINQSITGTFSSSDPKFFKEFINSADFCYRMDMSNRSSKDILDLANTLVKYVTKEFRQ
                     EECRHALEDMQIKTVPNGMGYKENPNPEHYNINVKWYESWKIEIEQTARYVKGIKNKY
                     PDKSIGILVPFNEQVTQVAKELRENNLTFEELGPNSLNKRKVINNIAYIIDFMLHCDD
                     VEKLIVVLNKVFIDTDNEEEIKYFLEELKNYSTEEIIYNFEFSKLDNDLIEFKEESDI
                     YLSFKRGIDIIKQILEYPIIRLDLLVLFIGKKLNLEKEDKAVLDYISFYIKYLISENI
                     NMDLEDVYNLLFDVKNRVFNHIIDVVYEINGYEPEPGSITLCNYHKSKGMEWDCVFLL
                     GLVEYNFPDNINQKFQSDKWYLKEKYKNPMAIIKSEVEAILKGSISTDYAHKTKIDSI
                     NEKIRLLYVGITRAKEMLVLSGSAYRDESDIGNKRKEQKPCIYLSRLNQHIIEKRSN"
     gene            9541..10371
                     /locus_tag="JAM15_04500"
     CDS             9541..10371
                     /locus_tag="JAM15_04500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HAT6797521.1"
                     /translation="MNDKLKYFSYSQNSINTYKSCPLKFKYKYIDRINWKNDDVGSRE
                     YYETLKTGRDFHLICERYFSNIPFGIYFNEDDKNSKKFLKWMENIKKVVPIEKGKTYL
                     PEYEVRMTLNGDIIQAKYDLVVIGNNNIEIWDWKTESKKIDYKHVENRIQTIVYMFLA
                     KEVIPKVLKMDINVKDINMRYYQPEFDDLPITILYDEEKHEANRNKIQNYISMIKNTN
                     YEEHTYEDNLYNDIEKVYNKEERMCYRNKKHCKYCEFNKLCNGKEIDYSILEAEIYGT
                     "
     gene            10361..13828
                     /gene="addB"
                     /locus_tag="JAM15_04505"
     CDS             10361..13828
                     /gene="addB"
                     /locus_tag="JAM15_04505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddB"
                     /protein_id="HAT6797522.1"
                     /translation="MGLRFVLGRSGSGKSTYILDEIKKEAQKNETTSIILLVPEQYTF
                     EAENRVSKLFLGKEKDKYLRVRVLSFKTLSNIVFSQVGGLTDVNINSSGKAMMVYRAI
                     EDVSEELNVFSKSKSQSGFVSSITDMISEMKQYNISPEMLENISGELDNETLSLKLKD
                     ISKIYNSFEGKLHENYVDAQDMLTSLASKIELSSYLDGACVYIDEFTGFTPNQYNVIK
                     SILNKSKSVNISLTVDDINYIGYSKSDMFSRTKFTYSKLTQLCNEEGIKILPQVNLNT
                     GVIKRFEKVKELQHLERFYNAYPYKIYSDQTENIKIKEFNNLYSEVEEIAREIVHLVR
                     DKNVRYRDITIATRDLNRYDFLVHSIFNEYNIPNFIDKKREAKSNPIVILIISALEMK
                     NRRYGYETMFRYLKSGLIGIDNDDINLLENYVLANGIKGKKWFDEKWDYRITQSLSGQ
                     ESEFELELKEKINEIKNRVLEPIVILQEKLRGKNRVKEICRYIYEFLLDINMPETIES
                     LIVNFKDKGELDVANQYSQVWDIVVDILDQMVELMGDEIISLEKFIKLITLGFDEYEL
                     GLVPPSIDQVLVSSVDRMKNPDTKYLYLVGTTDGVFPLITKDSGILSDNDRESLGNKG
                     IEVDIDSKTRSFEEQFLVYKALTSTSKNLTITYPISDHEGKTLRPSIIISRLKKIFPN
                     IENKSYLVEENKSTDKDILKKITVKSPTFNELINVIKNYDSDDYNTEEINSIWLDIYR
                     YYLKDEIYSSITKKVIKGLSYTNQVHKIEEKKIRSLYKSNSLSISRLEKYAECPFAYF
                     IQYGLKAKKRKEYSFTPPDLGTFIHNILDRFSKELLQDNLTWRDIDEKYIELKIGIIV
                     DEIILKIPGYILNSSERYKYLAYRLKNMLTTAITIISQQIKQGSFEPIDYEVKFGDNG
                     KYPPIKMVLENGQEVSLIGQIDRVDEFEEGENKYIRIIDYKSGNKSISLTEIYYGLQL
                     QLLVYLDAILESAKDEDININPAAILYCRINNPIAKFNEDKDDEEIQEAILKELRMKG
                     LVVKDSHIVKEMDKSLIDGERKNSLVIPVGLTKDGNVGKSTSAISYEDFKLLRKYVRH
                     AIKDLCEEMLSGEIRIAPYKHKDGTSCDFCDYSTICQFDSTIKDNKYKNLNNKSNEEI
                     IKMMKGDVN"
     gene            13828..17655
                     /gene="addA"
                     /locus_tag="JAM15_04510"
     CDS             13828..17655
                     /gene="addA"
                     /locus_tag="JAM15_04510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HAT6797523.1"
                     /translation="MSSPKWTKEQLEVIESRECNLLVAAAAGSGKTAVLVERIIQMIT
                     SRENPIDIDKLLVVTFTNAAASEMRERIGDAIGKALDENPENKHLQNQLVLLNKSSIT
                     TIHSFCLDVIKSNFHRINLDPNFRIGDQTECAILKQEAIEEVFEDLYEERDEGFLNLV
                     ESYAERGGDKEVQDIILGIYSFAMASPEPKKWLIDSAERFNIDENFDFSQSIWARAIL
                     DTVKIEINGLCLNMERALKEVESIEELETFAEKLSVEYKKIADISQACNKSWDEAYKK
                     MASMSFENYVKGVKRISKDAPSYIKESKEKAKTIRDKTKKSLESIVSATFNKDNDSIR
                     EEIKYLYNIVKPISNIVLRFEEEYSNKKREKGIIDFNDIEHFALNILTDVDEKGNIVP
                     SDIAVGYRNKFYEIFIDEYQDSNLVQEVLLKAVANTETPNRFMVGDVKQSIYRFRQAK
                     PELFLQKYNNYNDKKGSSHRKIMLYKNFRSREEVVDAVNYIFENIMNENIGEIEYTEK
                     ERLNLGANFNVDTDEKSIIGGATEIHLIQKDNKLDDDIINDKDDRINNKENEIEEEEK
                     LDNIQLEARMVGNIIKDLMKVNEDGKIQKVYDKGIDGYRPVEFRDIVILLRATSAWAP
                     VFADELMNMDIPTYADVGVGYFDTIEIKTILSLLQIIDNPMQDIPLISVLKSPIFGFT
                     PEDLIDIRVQSKDKIFYEVLKSTAEYDGFTDSQNETESEFIPSEECINKSKDFLIKLK
                     EFKEKSMYMSTDEFIWYLYTRTGYYAYVGALPGGSQRQANLKVLFERAKQFEETSLKG
                     IFNFVNFIEKLKKSSSDMGSAKTLGENANVVRIMSIHKSKGLEFPVVICSAMGKNFNT
                     QDFKKSILYHHNLGYGPQFVDYERRISFPSIAKEALKSKINIENLSEEMRVLYVAFTR
                     AKEKLIITGSTRNIQDSIKRWSNGIESLDTISQYEILKGKNFLDWIMPCVLRHRDLSN
                     LLEEVGLDAVFNVEHNSKWYGKLWNKNDILVEKKSDEEKESIEEILEKIDVDSPDSDY
                     YSEIEKKLNYIYPYEFSTRKPATISVTEIKKIQNNYEEELINTIFEQKVILKKPLFIQ
                     NEEEREKISGTERGTIVHLVMEVLDLKNVSSVNDIKSQIRGFVSKGIITEKQASIVNP
                     YKIYKFFASNIGKRMLNAEIINREKSIYAQVNMKDIYIYEKLINNDDKKLYDNESVML
                     RGIVDAYFEEDNQIVLVDYKTDFVNEENINQIIEKYKKQLDLYADIIETLTGKSVKEK
                     CIYLFGVDEAVCY"
     gene            17701..18912
                     /locus_tag="JAM15_04515"
     CDS             17701..18912
                     /locus_tag="JAM15_04515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HAT6797524.1"
                     /translation="MRFIHTSDWHLGKSLEGHSRIEEQAKFCEEFIKIVESNEIDMVI
                     IAGDVYDTSNPPAQAEKLFYQTVSRLANNGQRCVLIISGNHDNPERLSAITPLAHEQG
                     ILIYGYPLSATIEAKYKGFEITYATQGCTKLNINGENIVVATLPYPSEKRLNEVFSSE
                     DEFEKQKNYSEKVGDIFRSLEENFRSDTINIAVSHIFVIGGESTESERPIQLGGSFLV
                     ERKDLPEKAQYTALGHLHKQQKASERLNAYYSGSPLQYSKDERAYTKGAYIVDIKAGE
                     KPIIEDVYFNNYKPIEVFKCNGIEEALDICEQNQDREIWSYFEINTDEIISQNEIKKM
                     KELLKDIIEIKPIITSCYEQESVDIKEKSMAELFREFYSFSKGVEPKGELMDLFLDII
                     SEEGESADETN"
     gene            18899..22426
                     /locus_tag="JAM15_04520"
     CDS             18899..22426
                     /locus_tag="JAM15_04520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAT6797525.1"
                     /translation="MRPIRLELTGLNSYIDKQVIDFEKLIERGLFGIFGTTGSGKSTI
                     LDAITIAMYGNISRNTKEYINSVCDKAIISYEFEIGSKNTRRRYIVDRTIARSKTGTK
                     TSNARLIEVLNDNTQNVLADKVVEVNEKVAQVVGLTANDFTRSVVLPQDKFNEFLRLS
                     RADRRDMLERIFNLEKYGRSLGEKVKKRKNIQLQNLKDLKSKLSQYDGITEEVYNNIN
                     QELIELKNLEKDKNNALDLAQKSYEESKTVYEEQLKLEKNELRKNELDLKNSEIKEKI
                     ALVENDSNAKKVDPYISSVQNLEKKIDEDSFVVSNLEKKLAILNQELEVTKNRYEKIN
                     KIKNEEVPKLSEEKIRLQQAIKLEEELVLLDRELKELKESGINLNKTKVELEKVKQVS
                     ESRKDAVTKSIKEVEGKIDKVNISAELKQKIFLAYEYEKDYNNVLEEKNQKLNKLEEI
                     LKETENINLKVRYIDKDKNDVNRNLENLSLHLDVLLKKCPGKSADLLLKSEYVTELRS
                     KVNNTKENEIKKSSIQDELKIILESKFNTEREVNLLNEKLENNRKNRDDLEKELEELK
                     YLNLASELRRELKENMPCPVCGSKHHENHNITKYDENISFVKEKLEKLEKEKISIRNN
                     IEELNAKVSGYLSIEKMKTKELEDVKGKLGGIPSSQLLKKLDEEQRKLALLKSNIQEW
                     EKEKESTENKVTLAKEEKNKIEKEELKIRESLNNYKKLTRDLNIEIEGLENKCKKLKQ
                     EYLGLKTITKVSNLLSKVKEIRENEKELELLSTGHSNLLKNRDSLDIKIRENESKLHE
                     IEIELIKARELYVEKKLSRDNKYKEVINITKGDLAKNLLHNVEENICKILEQEESSKK
                     KLEEQRLEYEKNIAEKHNIDGRLKTAKEQYKDQKSTLNKLLAENKFESIYAVKRALLD
                     TDEVKKLIEEILEHEEEQKLLSFKIKSSKEKLNGRSIKKEYFEQLKDEIYNLKVEIGN
                     ISKDIGANQNQLITLKDSLDKINDFNKQLKVVEHNVDLLEELDKCVQGNKFVEYVSTN
                     QLKYIALEASKRLDGITKGRYALEIDSTLNFVMRDNFNGGERRSIDTLSGGETFLTSL
                     SLALALSSQIQLKGSAPLEFFFLDEGFGSLDSELLEIVIESLERLHSNNLSVGIISHV
                     EELKNRVPVKLLVSSSEAGIGSKVKIEYS"
     gene            22557..23810
                     /locus_tag="JAM15_04525"
     CDS             22557..23810
                     /locus_tag="JAM15_04525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HAT6797526.1"
                     /translation="MLESPNNLIQIIFLIVLLIGSAFFSASETALMSLSKIRIRYMQD
                     EGVKGAKLVSSLIENPNKLLSSILVGNNVVNIAATSISTSLFIGLMGEKGVALATAVM
                     TVLVLIFGEITPKTIAANNSEKVSLLVSKPIKAIIFILRPIVWIFNIITNIIFKLFGI
                     TNKGAKSFITEEELKTMVNVSHEEGVLEMEEREIINNVFEFGDMQAKNAMVQRIDMVA
                     IDMEDSYDEIIQVFKTEKLSRMPVYEETIDDIVGILNIKDIIFLSDEEIESFDIKNYM
                     REPFFTYEFKKITQLLEEMKLEKSQMAIVVDEYGGTSGLLTIEDLVEVIVGDIEDEYD
                     EEEDEIQVIKEDEYIVDGSTKIGDVNELIGVNLESEEFDSIGGFIIGHLSRLPEENEV
                     IEVDNIRFCIESIEKNRIKKIRIYT"
     gene            23959..25011
                     /gene="ytvI"
                     /locus_tag="JAM15_04530"
     CDS             23959..25011
                     /gene="ytvI"
                     /locus_tag="JAM15_04530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HAT6797527.1"
                     /translation="MSILENNFLYKLKNNTIFFCIYTLLFIFIYKAFPYIAPFFLGGI
                     IALMINPISQKLENKFRINKGISTLVLSFLAVAIVSTVTTIIVINSMKELMGFLNNIS
                     ANPEDISNTIMYFLNKINDFMKSFQEIANFDVEQLVNKFSGEVMQITKNLLTSILGLA
                     TSIPYIIIFIITLFIATYFIAKDLDKIENSFYNMFTVDVRKKVKNVKKEAGLSLVGYI
                     RAYTILMAITFFAIWGSFALFGLKYGLIVGFVGALMDLIPFLGIITIYLPVIVYYFLI
                     KNYFIAISMTVIFFVLSLIREILEPKLVSVNVGLNPLATLAAIFIGIQVKGIIGVIFC
                     LGLVCMHDILKKVDIF"
     gene            25098..26324
                     /gene="pepT"
                     /locus_tag="JAM15_04535"
     CDS             25098..26324
                     /gene="pepT"
                     /locus_tag="JAM15_04535"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HAT6797528.1"
                     /translation="MKQKLVERFLKYVSFDTTSNSQCENCPSSEGQRVLAKYIVEELK
                     TMGVDDVSLDENSYIMATLKGNTDGVDTIGFISHLDTIEDVSGKDIKPRIIENYDGKD
                     IVLNEALNVITYVKDSPELEEFKGDDLIVTDGTTLLGSDDKAGIAEIVTAIEYLINHP
                     EIKHGDIKIGFTPDEEIGRGADLFDVEKFGAKYAYTLDGGIVGELECENFNAANATIT
                     IHGRNVHPGSAKNKMVNAIHIAAEISEMFPADERPETTEGYEGFWHLNSIGGNVENVS
                     MAYIIRDHCREKFENRKSIMIENIEKINKKYDNRVELDLKDSYYNMKEKIEPVMFIVD
                     IAKEAMEELGIKPRLVPVRGGTDGARLSFNGLPCPNIFTGGLNFHGKNECIPVSSMEK
                     ATKLIVRIAEKYAERV"
     gene            26531..27583
                     /locus_tag="JAM15_04540"
     CDS             26531..27583
                     /locus_tag="JAM15_04540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp18"
                     /protein_id="HAT6797529.1"
                     /translation="MKIKSKKIIAFALSLGIMLPSCVYADTISKNQNAQVDMNNYLQG
                     RKSPKEEKLIGEDRFDTAIKISQSGWNNGSERVFLVNSNSLPDALASTPLASKLDAPI
                     LLTNKNSIPYNVTEEIKRLNPAEVILIGSEGAISSSVKESLEDMEVLVSRIGGADREE
                     TSLLLTRQLDDTGDLGVSKVAVVNGYNGLADATSISSPAASDNTAIIYTGKDSIRSEA
                     KNFITQNSTKTYIVGGEYSISKKLEGQLVNSERLAGTDRKDTNAKVLEKFYGKSSKVN
                     NMYFAKDGSGREADLVDGLAAGVLASKTKSPVVLASGSLSSAQKSFIKKVKADKFVQV
                     GGGKNSKPYAEALALQ"
     gene            complement(28001..28570)
                     /gene="yfcE"
                     /locus_tag="JAM15_04545"
     CDS             complement(28001..28570)
                     /gene="yfcE"
                     /locus_tag="JAM15_04545"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase"
                     /protein_id="HAT6797530.1"
                     /translation="MKIGIMSDTHGSLLYFEKALNVLSDCDVLLHGGDVLYHGPRNDI
                     PEGYNPKKFIETLNKLENIVIVKGNCDADVDQMVIEHPIQSPYVMSQFGEIRIILNHG
                     YIESEEEIIDKAKKMGGDILVLGHTHVKKLYMDDNLIVINPGSTSIPKDGSHSVAIID
                     IIKTDDEDELELDINLIDINTGNIININD"
     gene            complement(28595..29395)
                     /locus_tag="JAM15_04550"
     CDS             complement(28595..29395)
                     /locus_tag="JAM15_04550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+)/NADH kinase"
                     /protein_id="HAT6797531.1"
                     /translation="MKRIITINTNQLNKSLETKELLTRKLINAGFEVYSDIYPDTELI
                     ISIGGDGSFLRTVRDFDFPEIPIMGINTGHLGFFPDILPDKIDSFIEAYTKKDYIIQE
                     MSLLNAEVYTTTSGSNMLAVNEVVIRGDKSRTIHLNLSLDNKHIQNFSGDGMIISTST
                     GSTAYNYSAGGSIVDINLELMQITPLHPINTNAYRCFTSSIICSNESVIKIAPEYRFE
                     DSVLIVVDGVEHRFRQIENIKVSISDAKIKLLRMSNYEFWHRVSEKFL"
     gene            29530..30390
                     /locus_tag="JAM15_04555"
     CDS             29530..30390
                     /locus_tag="JAM15_04555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6797532.1"
                     /translation="MFSIRNITKKLGKFKLNNINLELKEGDIVGIIGPNGSGKTTLIK
                     IIMGIIDADEGEIELCNETIENSPISFKNNIGFVYDSLQFYPHLKVKEFRKIVSLFYK
                     NFDREKFDEYLNKFDIEENMHIENLSKGQSEKLMLSSALSHNAKLLILDEPTAGIDPI
                     VRTEIMQYLQDFVKNGSSSVIISTHNTDNLIKIADYLVFINRGNQIFTVKKELIEQEY
                     KIIRANKAELEAIKESIVGVKEYKYYNEALVKVGDSLKVKSLLIEIDKHKVKNPTIEE
                     LMYYYVNEVR"
     gene            30390..31076
                     /locus_tag="JAM15_04560"
     CDS             30390..31076
                     /locus_tag="JAM15_04560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HAT6797533.1"
                     /translation="MFNLIRKDLIIGISSDGIRNLKYILLFFVFYFFLNSISYYTVSI
                     VVSYLIFINTFECDYENDSRIFIRSMPVSIEDIVYSKYLLGVGLIISVTIIVSLLSKL
                     TSLVFFRNMVLNDVFFSVNIFLAILTILLPLIFKFGYGKMKVCGFIVSILIYFVYGSL
                     LKMISMIVYQVKHFNYSKVGGVYLSNYVTDIANTKYINLYSMTFLTIIIFIISMYFSI
                     KISKKNKFNY"
     gene            31128..31670
                     /locus_tag="JAM15_04565"
     CDS             31128..31670
                     /locus_tag="JAM15_04565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797534.1"
                     /translation="MKKFIKVSFFILGIFTLFIAINELVYRDMVSVKDYEINHLEEIV
                     FDFDSRRSRDIGTIVRFKISNNSKYSYKLNSAKMKFENCVENKKGMNKCSAYVNVDLF
                     NEKNSITERTLKYGIKPNNQGYVDFVIPKGLNFDYRYFNESGMSVEYKGEYIVNIPMA
                     KGLYLVVGKNNDTWNANIME"
     gene            31749..32216
                     /locus_tag="JAM15_04570"
     CDS             31749..32216
                     /locus_tag="JAM15_04570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HAT6797535.1"
                     /translation="MSISNVREYFKQFGKEDSILEFEQSSATVELAAEAAGVIPARIA
                     KTLSFKIGDDAILIVTAGDAKIDNKKYKAEFNCKAKMLTPEEVLEFTGHAIGGVCPFG
                     LKNSIKVYLDDSMKRFDTVFPACGSSNSAIELTCEEMEKFSKSEKWVDVCKNW"
     gene            32924..34060
                     /locus_tag="JAM15_04575"
     CDS             32924..34060
                     /locus_tag="JAM15_04575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HAT6797536.1"
                     /translation="MDLNSKKYQMLKELYVSFAENEVKPLATELDEEERFPYETVEKM
                     AKAGMMGIPYPKEYGGEGGDTVGYIMAVEELSRVCGTTGVILSAHTSLGSWPIYQYGN
                     EEQKQKFLRPLASGDKLGAFGLTEPNAGTDASGQQTTAVLDGDEYILNGSKIFITNAI
                     AGDIYVVMAMTDKSKGNKGISAFIVEKGTPGFSFGVKEKKMGIRGSATSELIFEDCRI
                     PKENLLGKEGQGFKIAMSTLDGGRIGIAAQALGLAQGALDETVKYVKERVQFGRPLSK
                     FQNTQFQLADMEVKVQAARHLVYQAAINKDLGKPYGVEAAMAKLFAAETAMEVTTKAV
                     QLHGGYGYTRDYPVERMMRDAKITEIYEGTSEVQRMVISGKLLK"
     gene            34119..34901
                     /locus_tag="JAM15_04580"
     CDS             34119..34901
                     /locus_tag="JAM15_04580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012064196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HAT6797537.1"
                     /translation="MNIVVCIKQVPDTTEVKLDPNTGTLIRDGVPSIINPDDKAGLEE
                     AIKLKEEMGAHVTVITMGPPQADMALKEALAMGADRGILLTDRAFAGADTWATSSALA
                     GALKNIDFDIIIAGRQAIDGDTAQVGPQIAEHLNLPSITYAEEIKTEGEYVLVKRQFE
                     DCCHDLKVKMPCLITTLKDMNTPRYMKVGRIYDAFENDVVETWTVKDIEVDPSNLGLK
                     GSPTSVFKSFTKSVKPAGTIYNEDAKTSAGIIIDKLKEKYII"
     gene            34920..35930
                     /locus_tag="JAM15_04585"
     CDS             34920..35930
                     /locus_tag="JAM15_04585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HAT6797538.1"
                     /translation="MGNVLVVIEQRENVIQTVSLELLGKATEIAKDYDTKVSALLLGS
                     KVEGLIDTLAHYGADEVIVVDDEALAVYTTEPYTKAAYEAIKAADPIVVLFGATSIGR
                     DLAPRVSARIHTGLTADCTGLAVAEDTKLLLMTRPAFGGNIMATIVCKDFRPQMSTVR
                     PGVMKKNEPDETKEAVINRFKVEFNDADKLVQVVQVIKEAKKQVKIEDAKILVSAGRG
                     MGGKENLDILYELAEIIGGEVSGSRATIDAGWLDKARQVGQTGKTVRPDLYIACGISG
                     AIQHIAGMEDAEFIVAINKNPEAPIFKYADVGIVGDVHKVLPELISQLSVAKEKGEVL
                     AN"
     gene            35949..36746
                     /locus_tag="JAM15_04590"
     CDS             35949..36746
                     /locus_tag="JAM15_04590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HAT6797539.1"
                     /translation="MSTSDVKVYENVAVEVDGNICTVKMNRPKALNAINSKTLEELYE
                     VFVDINNDETIDVVILTGEGKAFVAGADIAYMKDLDAVAAKDFSILGAKAFGEIENSK
                     KVVIAAVNGFALGGGCELAMACDIRIASAKAKFGQPEVTLGITPGYGGTQRLTRLVGM
                     AKAKELIFTGQVIKADEAEKIGLVNRVVEPDILIEEVEKLAKIIAKNAQLAVRYSKEA
                     IQLGAQTDINTGIDIESNLFGLCFSTRDQKEGMSAFVEKREANFIKG"
     gene            36844..37689
                     /locus_tag="JAM15_04595"
     CDS             36844..37689
                     /locus_tag="JAM15_04595"
                     /EC_number="1.1.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyryl-CoA dehydrogenase"
                     /protein_id="HAT6797540.1"
                     /translation="MKLAVIGSGTMGSGIVQTFASCGHDVCLKSRTQGAIDKCLALLD
                     KNLTKLVTKGKMDEATKAEILSHVSSTTNYEDLKDMDLIIEASVEDMNIKKDVFKLLD
                     ELCKEDTILATNTSSLSITEIASSTKRPDKVIGMHFFNPVPMMKLVEVISGQLTSKVT
                     FDTVFELSKSINKVPVDVSESPGFVVNRILIPMINEAVGIYADGVASKEEIDEAMKLG
                     ANHPMGPLALGDLIGLDVVLAIMNVLYTEFGDTKYRPHPLLAKMVRANQLGRKTKIGF
                     YDYNK"
     gene            37776..38951
                     /locus_tag="JAM15_04600"
     CDS             37776..38951
                     /locus_tag="JAM15_04600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012104016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HAT6797541.1"
                     /translation="MREVVIASAARTAVGSFGGAFKSVSAVELGVTAAKEAIKRANIT
                     PDMIDESLLGGVLTAGLGQNIARQIALGAGIPVEKPAMTINIVCGSGLRSVSMASQLI
                     ALGDADIMLVGGAENMSMSPYLVPSARYGARMGDAAFVDSMIKDGLSDIFNNYHMGIT
                     AENIAEQWNITREEQDELALASQNKAEKAQAEGKFDEEIVPVVIKGRKGDTVVDKDEY
                     IKPGTTMEKLAKLRPAFKKDGTVTAGNASGINDGAAMLVVMAKEKAEELGIEPLATIV
                     SYGTAGVDPKIMGYGPVPATKKALEAANMTIEDIDLVEANEAFAAQSVAVIRDLNIDM
                     NKVNVNGGAIAIGHPIGCSGARILTTLLYEMKRRDAKTGLATLCIGGGMGTTLIVKR"
     gene            39146..40048
                     /locus_tag="JAM15_04605"
     CDS             39146..40048
                     /locus_tag="JAM15_04605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAT6797542.1"
                     /translation="MFKKENQRYNLISYTNEEEMTLKEVLLDKLNFSVRSLSKMKREK
                     SVLVNGVYKKPSLKVYSGDLIEVKIDEEKANFEPQDLNLQIIYDDFDIIMVNKPPFMV
                     VHPTKSHYDKTIANGISYYIDNQKENVKIRFVNRLDMNTSGLVIVAKNAYAHHTLSTA
                     MSENKVEKKYITVVDGIIKENEGTIDEPIYRPTEDSIKRIIDERGQSSVTHYKVIERL
                     ENATVLEVSLETGRTHQIRVHMAHIGHGIIGDELYGYVDEELINRQALHAYKLEFEQP
                     RTKEKLKFKADIPEDMKELISKLR"
     gene            40062..41066
                     /locus_tag="JAM15_04610"
     CDS             40062..41066
                     /locus_tag="JAM15_04610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HAT6797543.1"
                     /translation="MIIHKFIIHVLDKNSDVPILNDFEGKVNQEVDGFFQKAIKRIAK
                     DEDLRKGVFKDYNDNLIKNCCEQIIYDESTFLKNSKEIASYLFDVMKINAALESCDLA
                     ICLYTIKDEKSVAILKLDYKKLYTHSIEFVDDKFNIQMVSNEIGIPETLRQKQGALIS
                     LSGINDEFHLRLLDKDAEKEGSESKFVTEFLNAKKIDDDKYKTKVFKNTAENWITNAL
                     SNDIKQAEDVRSILNYTLKEKHEVDINDFVDNSIKDDELKDSFKEHMEEKGLDESFSI
                     DKKWVEKKLKKRSIKTDNGFDIKGNLTDFEDPMKYTVKQNQDGTIDIIIKNVTFYEEK
                     "
     gene            complement(41210..41437)
                     /gene="acpP"
                     /locus_tag="JAM15_04615"
     CDS             complement(41210..41437)
                     /gene="acpP"
                     /locus_tag="JAM15_04615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HAT6797544.1"
                     /translation="MFEKIKEIIAEQLGVDNLDEITMEASLMDDLEADSLDAVEIIMA
                     LEDEFGIEIPDEEAENFKCIGDICKYIEENK"
     gene            41609..42034
                     /locus_tag="JAM15_04620"
     CDS             41609..42034
                     /locus_tag="JAM15_04620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797545.1"
                     /translation="MKYVGLLLTSVGMFLLIAVNFYYNSITLDMQRIEDYVMETNLIL
                     EDVAEKESYVSNEKEDYISRLMHVKKGIENSKTSFLIERYKEYKIKSIESLIYTISEE
                     KKDYLDEVDRYNKLGEKEINKLINKNFLEVTYLSITTYI"
     gene            42082..42288
                     /locus_tag="JAM15_04625"
     CDS             42082..42288
                     /locus_tag="JAM15_04625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797546.1"
                     /translation="MTKLEDNMERFFGGCEGFFGNKMLIIIVIVFLLLCTDILEDLLC
                     DDNIWIWVILIVLLLFNFDDGCCC"
     gene            42470..42649
                     /locus_tag="JAM15_04630"
     CDS             42470..42649
                     /locus_tag="JAM15_04630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797547.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFGDSWAEFDIMAWIPF
                     LIVLLILCCCGGCLE"
     gene            42683..42883
                     /locus_tag="JAM15_04635"
     CDS             42683..42883
                     /locus_tag="JAM15_04635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797548.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFEDCWRDIDIMSWIPF
                     LILLLITCSCGGFFDGEVGCGC"
     gene            43136..44152
                     /gene="ccpA"
                     /locus_tag="JAM15_04640"
     CDS             43136..44152
                     /gene="ccpA"
                     /locus_tag="JAM15_04640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator CcpA"
                     /protein_id="HAT6797549.1"
                     /translation="MKGNITIKDVAKQAGVSISTVSRVINDSKPVTDEVKQKVLEVIK
                     ETGYIPNPLARSLVTKKSQLIGVIVPEVSDSFVNEVLNGIEEVAKMYDYDILLANTYS
                     DKEQELKSINLLRAKQVEGIVMISWIVEQEHINYIQNCGIPATYISKTARNYDIYTVS
                     TSNEEATFDMTEHLIKKGHEKIAFIMTSKDDTVLEMERLAGYEKALSNNNIELDKSLI
                     KYGGTDYESGYNSMKELLDDGIIPHAAFVTGDEAAIGAINAICDAGYKVPEDISVAGF
                     NDVKIARMYRPKLTTVYQPLYDMGAVAIRMVIKLINKELIENKKIELPYRIVDRESVT
                     ERKK"
     gene            complement(44275..44673)
                     /locus_tag="JAM15_04645"
     CDS             complement(44275..44673)
                     /locus_tag="JAM15_04645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797550.1"
                     /translation="MKKLDTESLEKMAKQKNIDKDKIEKMADSYKGKSENELMEELIK
                     IGKNLDGRDEVVSKFKAFLDENQRKKLDNIMEKISDAENQRDTKPAKTKKAKPTKGKS
                     NSPAPKNTPGSQQKKSKSLFKKTKKSNPHE"
     gene            44885..45790
                     /locus_tag="JAM15_04650"
     CDS             44885..45790
                     /locus_tag="JAM15_04650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797551.1"
                     /translation="MNNLLFLIGVIALSNGNISIFDDKNKSKGNNRVRKNKKNTNDKL
                     SQSTHGNLRFDANDIKRGLRLMDLSEEDLEMGMEIITRTKKYMSRDERKILIKIESVL
                     DLVRGIKKLNNIDMVDTEDETDFFRKMDSDDKKNMMIKEIIDVFPEKRKNSVEKAIGM
                     KKKIDLFAELFLPDDFGEGGFSLSSLANINNLGSMNNLKLLGSLLRGDDSNNDDEDNN
                     DELNYEDEELDCEDKELDDDELTDEGEMEDNEDELVEDKNTGYENIENDEDIVYDEEL
                     YNINEQESEYNYNEKNTKTRAKKKR"
     gene            45905..46085
                     /gene="ssrS"
                     /locus_tag="JAM15_04655"
     ncRNA           45905..46085
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="JAM15_04655"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            46268..47476
                     /gene="cdeC"
                     /locus_tag="JAM15_04660"
     CDS             46268..47476
                     /gene="cdeC"
                     /locus_tag="JAM15_04660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeC"
                     /protein_id="HAT6797552.1"
                     /translation="MQDYKKNKRRMMNQPMSTMNEEEVYTDEINSEDMRGFKKSHHHN
                     GCNTDNKCECHDECNPCKPCKPNPCNPCKPNPCDDKCECHDKCKCDCEPCEMDSDECF
                     ENKCGPECCNPISPRNFSVSNAVPFAIEANRIFDTMQFQTFTDATGPNGEPLTFETEV
                     VEVFGSIPSAGQASVTIEKICLSNDGIVIDTGMTTLEDFDLDPLGDIVGRNCETTFEF
                     AVCGERNAECCRQGKGKSVAYKQRGLTVAVRNLVIELRGRCGCTEFVALAFPAVRAGG
                     GCKRRVDYVEFTFNTLSAPICLPADGRAVTLRQEYQTNLTVDCIGKSILKLECNECCE
                     PFYELIIPNDIDVVLCLQNTVSTLISEQIVVLASPNPIQPRLVDTFSKVCDFSQCEPN
                     HGSGKPSCHR"
     gene            complement(47576..48898)
                     /locus_tag="JAM15_04665"
     CDS             complement(47576..48898)
                     /locus_tag="JAM15_04665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAT6797553.1"
                     /translation="MKVPYLVLSTVILFISNFIVRIFGFLYKIFLSRALGETGLGIYH
                     MIFNFLMICLAVTTTGIPTALSCLVAKRKALNDRHNTNALFISTLYISFFVALIISIV
                     ASFNSSFLSLKFLKDAKLNLFILAVCPAIVIITLSNVLRGYYYGIKNVKIPAIGQIIE
                     QIGKILFVFLLVMYINNKSMNCYIALLGISIGELSNIIFMLICLWRDSSFDNRYIISI
                     KDFYNSSMETLKMSIPITCNRMSNILLQSISSMMIPSRLALSGMTYQQSLSMYGIVSG
                     MVMPFIFLPFTVGSALIVNLIPTISQEMALRKRKSVIKKIKYSILLTLFVGILSSIFF
                     YFFGKDLCILVFKNTLAGEYLKAMFLVPLFMSLNQTLSGILHSIRKELASSINTITGM
                     LIQLIALYVFLPIPELNIYAYIYTMTIVSIFTCLLHTIVLFKSLKSIR"
     gene            complement(48949..49743)
                     /locus_tag="JAM15_04670"
     CDS             complement(48949..49743)
                     /locus_tag="JAM15_04670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HAT6797554.1"
                     /translation="MFYDYHMHSSFSTDGKSTMEEMVKKSIELGLEEICFTDHVDYDV
                     YADDSFSIVYEDYFKSLETLQSKYKDKISIKKGIEFGVQTQLMDTYKKEAHQYPLDFI
                     ICSIHAIDTMDLYLGNYFKDKTQYEVYENYYLYLYNIVKNYKDYSVLGHLDLIKRYAP
                     YDTILDDRLFSDIIEETLKQAIYDGKGIEINTSCYRYNLPDLTPSKYILQMYKDLGGE
                     IITTGSDSHHISQVACEFDYIYSLLKNMGFKYVSKFNKLKPEFIKL"
     gene            49853..51298
                     /locus_tag="JAM15_04675"
     CDS             49853..51298
                     /locus_tag="JAM15_04675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAT6797555.1"
                     /translation="MEKYRIDLNEKKSTKYIQIFNHIKELIINKELVEHEKLPPIRKL
                     SNFLQVNNTTIVKVYELLENEGYVYKIIGSGTFVSSLNSYKSGIDNRKNKIIVQREDL
                     IHFDNGNPSNDMFPIDSFKNAVNMALSKDGSSIFEYDEGLGSEELREKMVEYLSDGNI
                     KTTKENIQIISGAQQGIDIVCKGLISYSDVVFMEEPSYNGAIEVFKSRGAKIISIPML
                     DDGIDIGILKLKLEKIKPRLIYIMPNFQNPTGISYSTYKKKKLIELAEEHDFYIIEDD
                     FISDFVFESKDNRTIRSYDDKNRVVYIKSFSKILMPGLRIGIVEMPNELLKKVLWAKY
                     SSDISTPGLIQKSMYYYMNNFDWKNYLSHIEKIYTDKYKLAKNLINDKLSGKLKVRKS
                     CGGINFFLELPRGYTSQAFTNFMLNKGVSMLPGTYFFDNLVDDRFFRINIARPSMEEL
                     EKGISVISDNIDEFFCEYKNKLDIKSNKLFY"
     gene            51327..51536
                     /locus_tag="JAM15_04680"
     CDS             51327..51536
                     /locus_tag="JAM15_04680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 domain-containing protein"
                     /protein_id="HAT6797556.1"
                     /translation="MFDKKKLDRINELAKKNKEGILSADEIKEREILRKEYLENFRAH
                     FRSRLDSVKVVSPEEYEQYMKNNKN"
     gene            51556..52950
                     /locus_tag="JAM15_04685"
     CDS             51556..52950
                     /locus_tag="JAM15_04685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HAT6797557.1"
                     /translation="MNLKYEFKNAWDFERKENTIEQIMQYSRNYMEFLSKSKTERLSV
                     KEIIKLAKENNYISIDEAMEKGSISCGDKIYVINKEKAVALFVIGKNYIEKGMKIIGS
                     HIDSPRLDLKPNPLYQESNLGFFKTHYYGGIKKYQWTAVPLALHGIVILNDGTKVDIS
                     IGEEDSDPVFCVTDLLIHLAGDQMQKKLSEGISGEALNILIGNIPLEDEEKEPITANI
                     LKILNEKYNIVEEDLLSAEIEVVPAGKARDLGLDRSMVLGYGHDDRVCSYAAVKAILE
                     TEQPEFTSVALCVDKEEIGSKGNTGMHSKFFENTVAELIALEGDYCDIKVRRALANSK
                     VLSADVSAGYDPNFGEAYEKRNSAYMGNGVVLTKYTGSRGKSGCNDANAEFMSEVKRI
                     FNKGNVVWQTAELGKVDQGGGGTIAHILANQGAEVIDCGVGVLNMHAPHEIVSKVDIY
                     EMYKGYKAFFNINL"
     gene            53189..53941
                     /locus_tag="JAM15_04690"
     CDS             53189..53941
                     /locus_tag="JAM15_04690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAT6797558.1"
                     /translation="MDEKRQKKEMDLEVNSFVPLYQQLYDNIKKQIASGIYKPGDKLP
                     SEGDLCKEFNISRITVRNALNELVKEDILCKKRGKGTYVTIPERIEATCAGNSFTNSC
                     HRINAKPSTKIISVLIKKADKQVAEALSIELEEKVICIKRLRLIDEVPVIFEVDYFRI
                     DYMFLLKEELEDKSLMEVISNNISTLPKRVENIFEVKHSNKEYSDYLKCASNMPLLKV
                     RQSVYTENNDVLYYNEQFIRSDKYKYAVSAEI"
     gene            53966..54379
                     /locus_tag="JAM15_04695"
     CDS             53966..54379
                     /locus_tag="JAM15_04695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIC"
                     /protein_id="HAT6797559.1"
                     /translation="MKKIILASHGDFSKGLLNAVKMIVGDLADCVSSYGLYPGQSASD
                     FALELEKTISEDIECEYIILSDLYGASVCTAMLRLTNLHNVKLFSGMNLNMVLELLTR
                     FSDELTVEDIEQLVEESRRGIQSVTLQIKEEEEVF"
     gene            54383..55126
                     /locus_tag="JAM15_04700"
     CDS             54383..55126
                     /locus_tag="JAM15_04700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane biogenesis protein"
                     /protein_id="HAT6797560.1"
                     /translation="MKKKGILSVFKSKKPIIAMIHLKGDTPEDIFERAKKEITIFEEN
                     GVDGIMLENYYGNYYDLERILEYVSKANLSIPYGVNCLNVDTMGFELATKYNASYIQV
                     DSVVGHVKPRDEATLEEFFKLQRSKCPAYLIGGVRFKYQPVLSENDVEEDLKIGMTRC
                     DAIAVTENATGQETSMEKIELFRKNLGDFPLVIAAGVTLENAKKQLELGDMAIIGSYF
                     KDNYKDFGNVSVEHVKTFMDEIKKIREEL"
     gene            55126..55596
                     /locus_tag="JAM15_04705"
     CDS             55126..55596
                     /locus_tag="JAM15_04705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAT6797561.1"
                     /translation="MIKLVRVDHRLIHGQVAFTWTKFLSTDCILIASDELLKDELRMA
                     GLKMAKPSNVKLVMKSIADSIKALNSGVTDKYNLLILCESVEDVYRLAKEVKAIKSIN
                     LGGTKSDDNRENISKAVHVSKDDIKMIKELDSEGVNVFVQLVPDDDATNVMKLI"
     gene            55613..56371
                     /locus_tag="JAM15_04710"
     CDS             55613..56371
                     /locus_tag="JAM15_04710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAT6797562.1"
                     /translation="MEFTQVILITLIAFFAYMHSFVGSTMHNRPIVVAPLVGLALGNL
                     HTGIVIGSTLELVFMGAFPVGASNPPDFVSGSIIATAFVILTGQDVSAAVVLAVPIAT
                     LVLLIDNFLMTVVLTWGAHIADRYAEEGNIEGVERVQLLFGIGNKLILAIIVGIGFSL
                     GVPVIEKILSFIPSYVTHGMDVAAGVIPAIGFAMLARMMLNKKTVAFLLLGFILVAYL
                     NITVTGVALFGLAIALIYVNFVGEKEVIVDDNEF"
     gene            56355..57197
                     /locus_tag="JAM15_04715"
     CDS             56355..57197
                     /locus_tag="JAM15_04715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAT6797563.1"
                     /translation="MTTSSKKLDTISPDSKITRKDFWKCFRRSLTLDSSWNYERMQNI
                     AYAYMMAPIIRRLYKDDKEKKSKALKRHLEFMSVTPHISTLLVGISGAMEEENAKNKE
                     FDANSINAVKSSLMGPVSGIGDSFFWGTLKLIAAGVGIALASQGNIMGPILFLLIINV
                     PHFIIRYICLDKGFKYGTQFFKDVSSSSIVSKVMEAASMLGLMVIGGMTASNVMLKLS
                     VNVGSGEWAEPIQTYLDQIMPCMLPAMIFGIMYWLLGKKVKTTTILISVMIICIVLAA
                     IGIV"
     gene            complement(57357..58262)
                     /locus_tag="JAM15_04720"
     CDS             complement(57357..58262)
                     /locus_tag="JAM15_04720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAT6797564.1"
                     /translation="MDFKQLEVFVAVAKHQSFSKAARELFLTQPTVSAHIQNLERELE
                     TVLINRSNKVITLTKSGEILYEHAIYILNNCKRAIYDIKEYSGKIEGIIDIACSSIPE
                     TYILPDFMKSFSMSYPDVKFSISHYDSQYAISEILNERISFGLVGSKINNPQIEYLDL
                     LDDELVLITPSDFKIDNKNNCIDIGELAYLNFIMRKEGSGTRNLILNTLSKNNFPVSK
                     LNVIAHVESNEAIKEMVRLGLGVSFISYISAIDYLNAGKIKCYKIKGVDFTRKFFFIY
                     SKKKTFSPLEDKFLNRLCEYFEIII"
BASE COUNT        23751 a         6137 c        10361 g        18242 t
ORIGIN      
        1 agatatatgt gtagttttta gagtgctaac tctaaaaact tagttttact aatttataaa
       61 aatttaatgc gggtgtagct caatggtaga gttctggcct tccaagccag ctgtgagggt
      121 tcgatcccct tcacccgctc caaaagatta tgtggttaca atagcagaga ggatacacct
      181 gttcccattc cgaacacaga agttaagctc tctagcgctg atggtacttg gtgggaaact
      241 gcctgggaga gtaggacgta gccacgtaat ctttttttgt tgtattaaat ttaataaacc
      301 tacaattatt atatgttttt atttgtcttt tatagatttt tttggcaata aatgatatag
      361 tgaagataat taaatatatt caatatattt aattttttta ttttttgttt ttataatttt
      421 tttagaagtt tattttttat gtacttattt ataattttgg gtaaaaacac tttgatatat
      481 tttcaaaagt taaaagatta aaaaacaaag tagaaattta tgttaaataa ggagattaat
      541 atgagaagaa atacaaaatt attaacaaca gggattcttt caatggcaat cgtcgcacct
      601 acaatggcat ttgctactga atctaatgct atggaaaata acgctgattt aaatataaac
      661 ttagagaaaa aaagtatcgt tttaggtagc aaatcaaaag tcagtgtcaa atttaaagaa
      721 aaaccagatg cagatagcat tacattaaag tataaatgct atgatatgcc attggataca
      781 actctaaatt acaatcaatc aactgagtca tatgaaggaa ctatcaatta taataaagac
      841 ccagaatatt taaatgtttg ggaactacaa gggataacaa taaacagcaa aaataatcct
      901 aaaactttaa acaaacaaga cctagaaaag atgggattaa atttaaaaga ctataatgta
      961 acacaggaat gtataattga agacataact tctagaaaag atgtaaataa atatttgaga
     1021 aaaacttctg cacctattac agaacttaca ggaagtgata ggtacgaaac agcagttaaa
     1081 ataagtcaag aaggctggaa aaatggttca gataaggtag ttataataaa tggagatgta
     1141 agtatagatg gcattatatc aactccactg gcaaccacat ataatgctcc aatacttttg
     1201 attgaaaaaa acaatgtgcc taatagtgta aaatcagaat taaagcgcct aaatcctaaa
     1261 gatgtaatta taattggaga tgagaatgct atttctaaaa ctactgctaa tcaaattaaa
     1321 tcgactgtaa atgctagtca aacacgtcta aagggctcta atagatatga gacatcttta
     1381 ttgatagcaa aggaaataga taaaaatcat gatgtggaaa aagtgtacat aacaaatgct
     1441 aatggtggag aagtggatgc acttactata gcagcaaaag caggtcaaga caagcaacca
     1501 attatattaa ctgataaaga tagtattaca gacaatacat ataaatggtt aaagagtgag
     1561 gatttacaaa atgcctattt tataggtgga cctcaaatga tatcaacaaa tgttataaat
     1621 aaagtaaatg atataactaa agataacgtg actaataata gagtatacgg agcagataga
     1681 cacgaaacaa atgcgaacgt aataaaaaaa ttctatacag atgatgagtt agaggctgtt
     1741 ttagtagcta aatcagatgt acttgttgat gctttagcag caggtccatt ggctgcgaac
     1801 ttaaaatctc caatacttat aacaccaaag acgtatgtat ctgcatacca taaagaaaac
     1861 ttagaagcta aatcggccaa taaggtatat aaaataggag gaggattgac ttctaaggta
     1921 atgaactcta tagcatcatc attatctaaa cacaatacaa ctccaacaga accaggaaat
     1981 agtgggggta agacagttat gattgaccca ggacatggtg gttcggacac tggaacaaca
     2041 ggtaaaccat tagggggtat taaagaaaaa gactatacat taaatacttc acttgcgaca
     2101 actgaatatt tacgttcaaa gggattcaat gtaataatga caagagacac agataagact
     2161 ttatctcttg gaaatagaac tgctttatct aactctttga gaccagattt atttacgagt
     2221 atacactata atgcatctga tacaactggg aatggtgtag aagtatttta taagcttaaa
     2281 gataaagatg gaggaactac taagactgta gctacaaata tattaaatag aattttagag
     2341 aaatttaatc taaaaaatag aggtgcaaaa acaagaacac tatcaactga ccctacaaaa
     2401 gattatttat atgttttaag aaataatgat atgccagctg tacttgtaga atgtgcattt
     2461 ttggataatg agaaagatat gagtttactt aatacatcaa ataaagtaaa agaaatgggt
     2521 acacaaatag gtaaaggcat agaagattca ttaaaatagt ctacaatgag agcatagaaa
     2581 aatttaaagt aaattaatct gcaattttaa atttaaacta aagttataag ataagaatgt
     2641 aattataata gtaataaaga ctgtatatac attgtgcata taagtgcgaa atgaggtata
     2701 tacagtcttt ttatgattaa ttgtaaaagg atttatatta tatgaagaat ttacatatct
     2761 taaggctaca gttaattgtc aagagttgga gtattcattt gtaatacaca ataaaagctt
     2821 aattactata ttttattgtg tgtttttgtg ttttttgtgg atttttatgt caataaatga
     2881 tatagtatag ataattaaat gtattaaata tatttaattt ttttattttt tgagttttat
     2941 aagtttattt ttatatatta tttatatttt gggctagata cactttgaca tattttcaaa
     3001 agttaaaaga ttaaaaataa agtagaaatt tatgttaagt aaggagatta atatgagaag
     3061 aaatacaaaa ttattaacaa cagggattct ttcaatggca attgttgcac ctacaatggc
     3121 atttgctact gaatctaatg ctatggaaaa taacgctgat ttaaatataa acttagagaa
     3181 aaaaagtatc gttttaggta gcaaatcaaa agttagtgtc aaatttaaag aaaaaccaga
     3241 tgcagatagc attacattaa agtataaatg ctatgacatg ccattggata caactctaaa
     3301 ttacaatcaa tcaactgggg catatgaagg aactatcaat tataaccaag atccagaata
     3361 tttaaatgtt tgggaactac aagggataac aataaacagc aaaaataatc ctaaaacttt
     3421 aaacaaacaa gacctagaaa agatgggatt aaatttaaaa gactataatg taacacagga
     3481 atgtataatt gaagacataa cttctagaaa agatgtaaat aaatatttga gaaaaacttc
     3541 ttcacctatt acagaactta caggaagtga taggtacgaa acagcagtta aaataagtaa
     3601 agagggctgg aaaaatggtt cagataaggt agttataata aatggagatg taagtataga
     3661 tggcattata tcaactccac tggcaaccac atataatgca ccaatacttt tggttgaaaa
     3721 aaacaatgtg cctgataatg taaaatcaga attaaagcgt ctaaatccta aagatgtaat
     3781 tataattgga gatgagaatg ctatttctaa aactactgct aatcaaatta aatcaactgt
     3841 aaatgctagt caaacacgtt taaatggttc taatatatat gagacatctt tattgatagc
     3901 aaaggaaata gataaaaatc atgatgtgga aaaagtatac ataacaaatg ctaatggcgg
     3961 agaagtggat gcacttacta tagcggcaaa agcaggtcaa gacaagcaac caattatatt
     4021 aactgataaa gatagtatta cagacaatac atataaatgg ttaaagagtg aggatttaca
     4081 aaatgcttac tttataggtg gccctcaaat gatatcaaca aatgttataa ataaggtaaa
     4141 tggaataact aaagatagtg ttactaataa tagagtatac ggagaagata gacacgaaac
     4201 aaatgcaaac gtaataaaaa aattctatac agatgatgag ctagaggctg ttttagtagc
     4261 taaatcagat gtacttgttg atgctttagc agcaggtcca ttggctgcga acttaaaatc
     4321 tccaatactt ataacaccaa agacgtatgt atctgcatac cataaagaaa acttagaagc
     4381 taaatcagct aataaggtat acaaaatagg aggaggattg acttctaagg taatgagctc
     4441 tatagcatca tcattatcta aacacaatac gactccaaca gaaccaggaa atagtggggg
     4501 caagacagtt atgattgacc cagggcatgg tggttcagca cctggaaatt catctggagg
     4561 aatgattgaa aaagattaca atttaaatac ttcacttgca acaactgaat atttacgttc
     4621 aaagggattc aatgtaataa tgacaagaga cacagataag actttatctc ttggaaatag
     4681 aactgctcta tctaattcat tgaaaccaga tttatttaca agtatacatt ataatggctc
     4741 aactaataaa caaggtcatg gtgtagaagt attttataag cttaaagata aaaatggagg
     4801 gactactaaa actgtagcta ccaatatatt aaatagaatt ttagagaaat ttaaacttac
     4861 aaatagaggt ataaaaacaa gagtacttcc tagtgattct acaaaagatt atttatacgt
     4921 tttaagaagt aatgatatgc cagctgtact tgtagaatgt gcatttttgg ataatgaaaa
     4981 tgatatgagt ttaataaact catctgcaaa agtaaaagaa atgggtacac aaataggtaa
     5041 aggaatagaa gattcattaa aataaatgga aataaaaata tttaaaaact taatgtaaat
     5101 ttatagttgt aaatttatac taaagtcaaa aaatgaaata taagtgtatc aatagtaaga
     5161 ctgtatgtac atttgcacat gtgaatgcaa gtatatatac agtctttttt tgtagttaaa
     5221 tgcaataata tgattgtgtt ttgtaaaata cacaatatga tataattaga taatatacac
     5281 ttaatttaat tgaggaaggt gattatatgg aatatttatt tgaaaaaagt agtttaaaag
     5341 aatatggaaa tgaagcttta gataaatata gagaattatt agataaaact ggtaataatt
     5401 caaggtgtat tcttttgtta gtaccaaaca ataacacaaa gatacgatat gaaagggctc
     5461 taagattaaa ttatagtgaa gaactgaaaa taacaacata tataagtttt gtgaagaaag
     5521 aattagttaa atactggcca ctaataatag aaaaatgtga tgaaataaat acaaaggttg
     5581 tatctccaac atttatatca aatagtttaa gtgaatattt aatagtgcaa aaagttaagg
     5641 aaaaaaggat acaagaagga tattttgaag atattacagg aaccaataaa tccatagcaa
     5701 atagtataat gactaacata aataaatctg catttaattt aattgatttt gattttattg
     5761 gagaaaaaat atattcatca aagaaaaata aagatagtat atatagattt tcatacactc
     5821 agatggatga aattatatca tattatataa attcgttact atcaaattca attttagata
     5881 atgcattaag catatattta tacaatcaat acctacttaa tgatgatttt tatttaaaaa
     5941 acttatttac agaagtgaga tatataattg tggatagtct tgaaagctca agtaatgcag
     6001 aagttgattt tataacagaa gcattggata atacattaca aagttatata tattttgatt
     6061 atagtaggga ttattctgta tttaataatg tggatataga ctatataaat gagaaaataa
     6121 tatcaaaaat taagcctaaa gaagaaaata ttaaaaagaa ggagattaga atagaagatt
     6181 tatacttatt acctgcaaat atagaattaa atcaatcaag tcaattatac aatgaaatgt
     6241 tagatttaat aagtgaaaaa gttatatctc ttatagaaga agatgtatct ccaagagata
     6301 tagcaattat atctcctata aacaatagta tattggagca tcaaattaga gattctttga
     6361 tagaaaaaaa tatagatgtt tttagtacta agaaggataa aaaagctgta gattatccat
     6421 atgggaatgc attggtagtg gctacatgta tattttatgg atatttagat tttataaaag
     6481 atgatgaata cttaagcttt ttagaaactc ttttagaaat aaataggata aaagcattta
     6541 agatttttaa tgaaacaaga catttaagta ttgataatat agatgaacat agtcagtatc
     6601 gtgatatttt acagtatatt gaagaaaaaa agaagagtga tataaaaata catgaatttt
     6661 taactcaatt ttacatagat aaaatgttaa atttaaaaga aggtaaaaag aatgttgggt
     6721 tatgtaaaaa gataatagct gaaagtgagt cttttagtga aagtttaagt ctacttagga
     6781 tgaaaaaaga aaagatattt atagaagctt taaaaagtac aataaacgat tattactctg
     6841 ttgtcgatat agaagagttg aaatccaaag acaaaatagt aataactact ccttattcat
     6901 atatatcatc aaatatagat agaagtatac aaatatgggt agatatagga agtaatgctt
     6961 ggaatatgaa aatagaaaaa gatataagta atttaattgt acttagaaaa tcttttgaag
     7021 aaaaaaagat ttatacaaat gaaatggaag aatattataa aaaatattat ctatacaata
     7081 cagtatataa tttgttatta aatgcaaaga aaatctatgc atttaaaagt gaatatgcga
     7141 ttaatggtta tatccaagag agtatattat atagtatact tttaaaaatc tcacataaag
     7201 gagataaaaa ttatgattaa tataaattat agagaagacc agataccaat aataaattac
     7261 gataatggta ctatggcagt accagcagta ccaggtgctg gaaaaacatt tataataaca
     7321 aatttagtag ctaaactatt acttgaacag aaacataagg gtggtaaaat attaattctt
     7381 acatatatga atagtgctgt aaataatttt aaaggtagaa taagaaagat tcttgaagag
     7441 aataaaatag atgatactaa ttcgtatgaa gtaatgacta tacacagttt ggctgtaaaa
     7501 ataataaagg aaaagccaga agttgtaatg ttaagtgagg attttaacat agctgacgat
     7561 ttgcaaaaaa gtattatatt aaatgaatgt ataagtagat ttagatttga aggtggagaa
     7621 agagctttta gatggttttt aaaggagcaa aaagatgaac gctggaaaga aataactctt
     7681 gaagcctggg aaagaggttt ttttgaattt gcaggaaatg caataagtga acttaagtat
     7741 aagggaattt ctccagataa acttgaagaa atattgtcaa ggggacacaa aggaatgctt
     7801 aaaattattt taccaatata taaattgtat gatagaaaat taaagcaaaa tggattgcta
     7861 gattatgatg atatattaat tttagcagaa aaaactttaa gcttagacga agggcttaga
     7921 aagaagtttc aaactagata caaatatata tttgaagatg agtgtcagga ctcaaatgaa
     7981 attcaaggta atataataaa aattatatct agtgaaaata aaaacctagt tagagttgga
     8041 gatataaatc agagtataac aggaacattt tcatcatcag accctaaatt ttttaaagaa
     8101 tttataaata gtgcagattt ctgttatagg atggatatgt caaatcgaag ttcaaaagat
     8161 atacttgatt tagcaaacac tcttgtcaag tatgttacaa aggaatttag acaagaagaa
     8221 tgtagacatg ctcttgaaga tatgcaaata aaaactgtgc caaatggaat gggatataaa
     8281 gaaaatccta atccagaaca ttataatata aatgtaaagt ggtatgagag ttggaaaatt
     8341 gaaatagagc aaactgctag atacgttaag ggtataaaaa ataaatatcc agataaaagt
     8401 ataggtatat tggttccatt taatgaacaa gtgacacaag ttgctaaaga acttagagag
     8461 aataatctaa cctttgaaga attaggacca aattctttga ataaaaggaa ggttataaac
     8521 aacatagcat atattattga ttttatgtta cattgtgatg atgtagaaaa gttaatagtt
     8581 gtacttaata aagtttttat agatactgat aatgaagaag aaataaagta ttttttagaa
     8641 gaattaaaaa actattctac cgaagaaatt atttataatt ttgaatttag taagttagat
     8701 aatgatttaa tagaatttaa agaagaaagt gacatatatt taagttttaa aagaggaata
     8761 gatattataa aacagatatt agaatatcca ataataaggt tagacctctt agttttgttt
     8821 attgggaaaa aacttaattt agaaaaagaa gataaagctg tactggatta tatatctttt
     8881 tatataaagt atctaatatc agaaaatata aatatggatt tagaagatgt atataattta
     8941 ttgtttgatg taaagaatag ggtgtttaat catataatag atgtggtata tgagataaat
     9001 ggatatgaac cagagcccgg tagtataaca ctatgtaact atcataagtc aaaggggatg
     9061 gaatgggatt gtgtgttttt actaggtctt gttgaatata atttccctga caatattaat
     9121 caaaagtttc agagtgataa atggtatcta aaagaaaaat ataaaaaccc tatggcaatt
     9181 attaaatcag aagttgaagc tatattaaaa ggaagtattt caacagatta tgctcataaa
     9241 acgaagattg attctataaa tgaaaagatt agacttttat atgtagggat tactagagca
     9301 aaggaaatgt tagtactttc aggaagtgct tatagagatg aaagtgatat agggaataag
     9361 agaaaagagc aaaaaccatg tatatattta agcagactta atcaacatat tattgaaaaa
     9421 aggtcaaatt aatatataat aagttattaa aagattgctt gaaatatatc taaaagggga
     9481 taaaacaata tgtacagtaa gtaactacta aaaaataaag ttaagagaga agtgatatga
     9541 gtgaacgata aattaaaata tttttcttat agtcaaaatt caatcaacac atataaatca
     9601 tgtccattga aatttaaata taaatatatt gatagaataa attggaaaaa tgatgatgtt
     9661 ggtagtagag agtattatga aactttaaaa acaggaagag attttcattt gatttgtgaa
     9721 agatatttta gcaatatacc ttttggaatc tattttaatg aggatgataa aaatagtaaa
     9781 aagtttttaa agtggatgga aaatataaaa aaagttgttc ctattgaaaa aggaaaaacg
     9841 tatttgccag aatatgaagt aaggatgaca ttaaatgggg atataataca ggcaaagtat
     9901 gatttagttg taattggaaa taacaatata gaaatatggg attggaaaac cgagtctaaa
     9961 aagattgact ataaacacgt agaaaataga atacaaacta ttgtttatat gtttttagca
    10021 aaagaagtaa tacctaaagt tttaaaaatg gacataaatg ttaaagatat aaatatgaga
    10081 tattatcaac ctgaatttga tgacttacca attaccattt tatatgatga agaaaaacat
    10141 gaagcaaata gaaataaaat tcaaaattat ataagtatga taaaaaacac taattatgaa
    10201 gaacatacat acgaagacaa tctatacaat gatatagaaa aggtatataa taaagaagaa
    10261 cgtatgtgct atagaaataa aaagcattgc aagtattgtg aatttaataa gttatgtaat
    10321 ggcaaagaaa tagattatag tattttggag gcggaaattt atgggactta ggtttgtatt
    10381 aggtagaagt ggaagtggaa aatccaccta tatactagat gagattaaaa aagaagctca
    10441 aaaaaatgaa acgacatcaa ttatactttt agttccagaa cagtacacat ttgaggctga
    10501 aaatagagta agtaaactat ttttaggaaa agaaaaagat aagtatctaa gagttagggt
    10561 gcttagcttt aagacactaa gtaatatagt tttttctcaa gtaggaggat tgacagatgt
    10621 aaatataaat tctagtggaa aagcaatgat ggtatataga gctattgaag atgtaagtga
    10681 agaattaaat gtattttcaa aatcaaaatc gcagtctggt tttgtaagct caattacaga
    10741 tatgatatca gaaatgaaac aatacaatat aagccctgaa atgttagaaa atatatctgg
    10801 agaattggat aatgaaactt taagtttaaa attaaaagat ataagtaaaa tatataattc
    10861 ttttgaaggg aaattgcatg aaaattatgt agatgctcaa gatatgttaa cttcattggc
    10921 aagtaaaatt gaattaagca gttatttaga tggagcttgt gtttatatag atgaatttac
    10981 aggttttaca ccaaatcagt acaatgtcat aaagagtata ttaaataagt ctaaaagtgt
    11041 taatatctct ttgactgtag atgatatcaa ctatattggg tacagtaagt ctgatatgtt
    11101 ttccagaacg aaatttactt attcaaaatt gactcaattg tgcaacgaag aaggcataaa
    11161 aatattgcca caagtaaatt taaacacagg tgttataaaa agatttgaaa aagttaagga
    11221 attacagcac ttagaaagat tttataatgc ttatccatat aaaatatatt cagatcaaac
    11281 tgaaaatata aagataaaag agtttaacaa tttatattca gaggtggaag agatagccag
    11341 agagattgta catttagtta gagataagaa tgtcagatat agagatataa ccattgctac
    11401 aagagattta aatagatatg attttttagt acactctata tttaatgaat ataatatacc
    11461 aaactttata gacaagaaga gagaggcaaa aagtaatcca atagttattt taattatttc
    11521 agctttagaa atgaagaata gacgatatgg gtatgaaact atgtttaggt atttaaaaag
    11581 tggacttata ggaattgata atgatgatat aaatttacta gaaaattatg tgttggctaa
    11641 tggtattaaa ggtaaaaaat ggtttgatga aaaatgggat tatagaataa cacaaagtct
    11701 ttcaggtcaa gaaagtgaat ttgaactgga attaaaagag aaaataaatg aaataaaaaa
    11761 tagagtatta gagcctatag taattttaca agaaaaatta agaggaaaaa atagagtaaa
    11821 agaaatctgt agatatatat atgaattttt attagatata aatatgccag aaactataga
    11881 aagtttaata gtaaatttta aggataaagg ggaacttgat gttgcaaatc aatactcaca
    11941 agtttgggac atagtagtgg acatattaga ccaaatggtg gaacttatgg gtgatgaaat
    12001 aatttcttta gaaaaattta taaaattaat aaccttaggc tttgatgaat atgaattagg
    12061 actggttcct cctagtatag accaggtact tgtaagtagt gtggatagaa tgaaaaatcc
    12121 agacacgaaa tatttatacc tagttggaac tactgatggt gtgtttccac tgattacaaa
    12181 ggatagtgga atattgagtg ataatgatag ggaaagtctt ggaaacaaag gaatcgaagt
    12241 tgatattgat agtaagacta ggagttttga agaacagttt cttgtatata aagctcttac
    12301 ttcgacatct aagaatttaa ccataacata tccaatatca gaccatgaag gtaaaacgct
    12361 tagaccatca ataattatat caagacttaa gaagatattt ccaaatatag aaaataaaag
    12421 ttatttagtg gaagaaaata aaagcactga taaagatata cttaaaaaaa taacggttaa
    12481 atcccctaca tttaatgaac ttataaacgt aataaaaaat tatgacagtg atgattacaa
    12541 tacagaagag attaatagta tttggttaga tatatatagg tactatttaa aagatgaaat
    12601 ctatagttct ataacaaaaa aagttataaa aggtcttagt tatactaatc aagttcataa
    12661 gattgaagag aaaaaaataa ggtcattgta taaaagtaat tctcttagca tatctaggct
    12721 tgaaaaatat gctgaatgtc catttgctta ttttatacaa tatggtctaa aagcaaaaaa
    12781 gcgtaaagag tattcattta caccaccaga tttaggaact tttattcata atattttaga
    12841 taggttttca aaagaacttt tacaagataa tttaacttgg agagatattg atgaaaaata
    12901 tatagaatta aagataggta taatagttga tgaaataatt ttaaagatac caggatatat
    12961 attaaatagt tctgagaggt ataaatacct tgcatataga ttaaagaata tgttgacaac
    13021 tgctataact ataattagtc agcaaataaa acaaggttca tttgaaccaa tagattatga
    13081 agttaaattt ggcgacaatg gaaaatatcc acctataaaa atggtgttag aaaatggaca
    13141 agaagtaagt ttaattggac aaatagatag agttgatgaa tttgaagaag gagaaaataa
    13201 atatataaga ataatagatt ataagtcagg caataagtcc ataagtctaa cagaaatata
    13261 ttatggtcta caattacaat tacttgtgta tttagatgca atccttgaaa gtgcaaagga
    13321 tgaagatata aatataaatc cagctgcaat actatattgt agaataaata atccaatagc
    13381 aaaatttaat gaagataaag atgatgaaga aatacaagaa gcaatattaa aagaacttag
    13441 aatgaagggg cttgtagtaa aagactctca catagttaaa gagatggata aatcattaat
    13501 agatggagaa aggaaaaact ctttagtaat accagtaggt cttactaagg atggaaatgt
    13561 aggtaaaagt acttcagcaa taagctatga ggatttcaaa ctgcttagaa aatatgtaag
    13621 gcatgctata aaggatttat gtgaagaaat gttaagtgga gaaatacgta tagctccata
    13681 taaacataaa gatggaacat catgtgactt ttgtgattac tctactatat gtcagtttga
    13741 ttcaactata aaagataaca agtataaaaa tttaaataat aagagtaatg aagagataat
    13801 aaaaatgatg aaaggagatg ttaattagtg agttctccta aatggacaaa agagcaatta
    13861 gaagttatag aaagtagaga atgcaattta ttggttgctg ctgctgctgg ttcaggaaaa
    13921 acagccgttc tagttgagcg tataattcaa atgataacaa gtagagaaaa tccaattgat
    13981 atagataagt tattagttgt tacatttact aatgctgctg cgtcagaaat gagagagagg
    14041 ataggggatg ctataggaaa agccttagat gaaaacccag aaaataaaca tttacaaaac
    14101 caacttgttt tattaaataa atctagtatt acaacaatac actcattctg tttggatgtt
    14161 ataaaatcaa actttcatag aataaactta gaccctaatt tcagaatagg agaccaaact
    14221 gaatgtgcta ttttgaaaca agaagcaata gaggaagtat ttgaagattt atatgaagaa
    14281 agagatgagg ggtttttaaa tttagttgaa agttatgcag aaagaggagg agataaagaa
    14341 gtacaagata ttatcttggg aatatattca tttgcaatgg cttctcctga acctaaaaaa
    14401 tggttgattg actcagcaga acgatttaat attgatgaaa attttgattt ttcacagtct
    14461 atttgggcta gagctatatt agacactgta aaaatagaga ttaatggtct ttgtctaaat
    14521 atggaaaggg cattaaaaga agtggaatca atagaagaat tagaaacttt tgcagaaaag
    14581 ttatccgttg aatataaaaa aattgctgac atttcacaag catgtaataa atcttgggat
    14641 gaggcatata aaaagatggc aagtatgtct tttgaaaatt atgtaaaagg agtaaaaaga
    14701 atttcaaaag atgctccttc atatataaaa gaatcaaaag aaaaggcaaa aactataaga
    14761 gataagacta agaagtcttt agaaagtata gtaagtgcta cattcaataa agataatgat
    14821 tctattagag aagaaataaa atatctttat aacatagtta aaccaatatc taatattgta
    14881 ctgagatttg aagaggaata tagcaataag aaaagagaaa aaggaataat agattttaac
    14941 gatatagagc attttgcatt aaatatactt acagatgtag atgaaaaagg taatattgta
    15001 ccttctgata tagcagttgg atatagaaac aagttttatg aaatatttat agatgaatat
    15061 caggatagta atctagtgca ggaagtactg cttaaagctg ttgcaaatac agaaactcca
    15121 aatagattta tggttggtga tgtaaaacag agtatatata gatttagaca agcaaagcca
    15181 gaattatttt tgcaaaaata taataactat aatgataaaa agggaagttc ccatagaaaa
    15241 ataatgcttt acaaaaattt tagaagtaga gaagaagttg tagatgctgt aaattatata
    15301 tttgaaaata taatgaatga gaatatagga gaaattgaat atacagaaaa agaaagacta
    15361 aatttaggtg caaattttaa tgtggataca gacgagaaat ctattattgg tggagcaacg
    15421 gagatacacc taatacaaaa agataataaa cttgatgatg atattataaa tgataaagac
    15481 gatagaatta ataacaaaga aaatgaaata gaggaagaag aaaaattaga taatatacaa
    15541 cttgaggcta gaatggttgg aaacattatc aaagatttaa tgaaagtcaa tgaagatgga
    15601 aaaattcaaa aggtctatga taagggaata gatggatata gacctgtgga atttagagat
    15661 atagttattc ttttaagagc tacatctgca tgggctccag tgtttgcaga tgaattgatg
    15721 aatatggata taccaacata tgctgatgtt ggagtggggt attttgatac gattgaaata
    15781 aaaacaatat tgtcattact tcaaataata gataatccaa tgcaagatat acctcttata
    15841 tctgtattaa aatcacctat atttggattt acaccagagg atttgattga tattagagtt
    15901 cagagtaaag ataaaatttt ttatgaggtt ttaaaaagta cagcagagta tgatggattt
    15961 acagattctc aaaatgaaac tgagtctgag tttataccaa gtgaagagtg cataaacaaa
    16021 agtaaagatt ttttaattaa gctaaaggaa tttaaagaaa agtcaatgta catgagtaca
    16081 gatgaattta tatggtactt atacacaagg actggatact atgcttatgt tggagcattg
    16141 ccaggtggaa gtcaaagaca agctaattta aaagtattgt ttgagagagc aaaacaattt
    16201 gaagaaacca gtcttaaagg aatattcaac tttgtaaatt ttatagagaa attaaaaaaa
    16261 tctagttctg atatgggaag tgcaaaaaca cttggtgaga atgcaaatgt tgttagaata
    16321 atgagtattc ataaaagtaa aggtctagaa tttccagtag tcatatgctc tgcaatgggt
    16381 aaaaatttca atactcaaga ttttaaaaag agtattttat atcatcataa tttagggtat
    16441 ggacctcaat ttgtagacta tgagagaagg atttcttttc caagtatagc caaagaagca
    16501 ttaaaaagca aaataaatat agaaaattta tcagaagaga tgagagtttt atatgttgca
    16561 tttacaagag ctaaagaaaa attgattata actggttcta ctagaaatat acaagatagt
    16621 ataaagagat ggtcaaatgg aattgaaagt ttagatacaa tatcacaata cgagatatta
    16681 aaaggtaaaa attttttaga ttggataatg ccttgtgtat taagacatag ggatttatct
    16741 aatctactag aagaagtagg attagatgca gtttttaatg ttgaacataa ttcaaaatgg
    16801 tatggaaagt tgtggaataa gaatgatatt ttagtggaaa agaagagtga tgaagaaaaa
    16861 gaaagtattg aagaaattct tgaaaaaata gatgtagata gtccggacag tgattattac
    16921 agtgaaatag aaaaaaaatt aaactatata tatccatatg aatttagtac aagaaaacct
    16981 gctactatat ctgttacaga aataaaaaag atacaaaata attatgaaga agagttaata
    17041 aatactatat ttgaacaaaa agtaatatta aaaaagcctc tatttattca aaatgaagaa
    17101 gaaagagaaa aaataagtgg aacagaaaga ggtacaatag tccatttagt tatggaggtt
    17161 ttagacttaa aaaatgtaag tagtgtaaat gatataaaat cacaaataag aggttttgtt
    17221 tcaaaaggta taataacaga aaaacaagct agtatagtaa atccatataa aatatataaa
    17281 ttttttgcct ctaacatagg aaaaagaatg ttgaatgctg aaattataaa tagagaaaaa
    17341 tcaatttatg cacaagtaaa tatgaaagac atatatattt atgaaaagct tataaacaat
    17401 gatgataaaa aactttatga taatgaaagt gtcatgttaa gaggtatagt tgatgcttat
    17461 tttgaagaag ataatcaaat agttttggtg gattataaaa cagattttgt aaatgaggaa
    17521 aatataaatc aaataataga gaaatataaa aaacagttgg atttatatgc agatattatt
    17581 gaaactttaa ctggtaagtc agtaaaagag aaatgtatat atttatttgg agttgatgaa
    17641 gctgtttgtt attagttttt atatataaat taaacctaaa agatagagga aggggaaaaa
    17701 atgagattta ttcatacatc agattggcat ctagggaagt ccctagaagg ccattctaga
    17761 attgaggaac aagcaaagtt ttgtgaggaa tttataaaaa tagtagaatc aaatgaaata
    17821 gatatggtta taattgctgg agatgtatat gatacttcta atcccccagc acaagcagaa
    17881 aaactatttt atcagactgt atcaagactt gccaataatg gtcagaggtg tgtattaata
    17941 atttcaggaa atcatgataa tccagagaga ctttctgcaa taacacctct agcacatgaa
    18001 caggggatac ttatatatgg ttatccatta agtgctacga tagaagctaa gtataaaggg
    18061 tttgaaataa catatgcaac tcagggatgt acaaaactga atataaatgg agaaaatatt
    18121 gtggttgcta cattacctta tccaagtgaa aaaagattaa atgaagtttt ttcaagtgaa
    18181 gatgagtttg agaaacaaaa aaattattct gaaaaggtag gagatatatt tagaagttta
    18241 gaagaaaatt ttagaagtga tactataaat atagccgtat cacatatatt tgtaataggt
    18301 ggagagagta ctgaatcaga aagacctata caattaggtg gaagtttttt agttgaaaga
    18361 aaagatttgc cagaaaaggc tcaatatact gcactaggtc atttacataa acaacaaaaa
    18421 gcttccgaac gtttaaatgc atactattct ggttctccac ttcaatatag caaggatgaa
    18481 agagcgtata ccaaaggggc atacatagtg gatataaaag ctggagaaaa accaataatt
    18541 gaagatgtat attttaataa ttacaaacct atagaagtat ttaaatgtaa tggaatagaa
    18601 gaagcactag atatatgtga gcaaaatcaa gatagagaga tttggtcata ttttgaaata
    18661 aatactgatg agataatatc acagaatgaa attaaaaaaa tgaaggaact attaaaagac
    18721 ataatagaaa taaaaccaat aataacatct tgttatgaac aagaaagtgt agatataaaa
    18781 gaaaagtcta tggcagagtt gtttagagag ttctattctt ttagtaaagg tgtagagcca
    18841 aaaggagaac ttatggattt atttctagat ataataagtg aagaaggtga atcagcagat
    18901 gagaccaatt agattagaac ttacagggct taatagctat attgataaac aagttataga
    18961 ctttgaaaaa ttaattgaaa gaggtttgtt tgggatattt ggaactactg gaagtggaaa
    19021 atctacaatc ttagatgcaa taactattgc tatgtatgga aatatatcca gaaatacaaa
    19081 agaatatata aacagtgtgt gcgataaggc aattatatca tacgagtttg agataggaag
    19141 caaaaacact agaagaagat acattgtaga tagaaccatt gctagaagca aaacaggaac
    19201 aaagacctct aatgctagat taatagaagt attgaatgac aatacccaaa atgttttagc
    19261 tgataaagtt gtggaagtaa atgaaaaagt agcgcaggtt gtaggattaa cggcaaatga
    19321 ttttactagg tcagtagttt taccacaaga taaatttaat gagtttctaa gattatcacg
    19381 tgcagataga agagacatgt tagagagaat ttttaatctt gagaaatatg gaagaagtct
    19441 tggagaaaaa gtgaaaaaga gaaaaaatat acagttacaa aatttaaaag atttgaaatc
    19501 aaaattaagt caatatgatg gaattacaga ggaagtatac aacaatataa accaagaatt
    19561 aatagagtta aaaaatttgg aaaaagataa gaataatgct ttagacctag ctcaaaaatc
    19621 ttatgaagaa agtaaaacag tatatgaaga acaattaaag ttagaaaaaa atgaacttag
    19681 aaaaaatgag cttgatttaa aaaatagtga gataaaagaa aagattgctc ttgtagaaaa
    19741 tgatagtaat gctaaaaagg tagacccata cataagttca gttcaaaatc tagaaaaaaa
    19801 gatagatgaa gatagctttg tagtaagtaa tttagaaaag aaattagcaa tattaaatca
    19861 ggagcttgaa gttacaaaaa atagatatga aaaaataaac aaaattaaga atgaagaagt
    19921 ccctaaattg agtgaagaaa aaataagatt gcaacaagca ataaaattag aagaagagtt
    19981 agttttatta gatagagagt taaaagagct aaaagaaagt ggaattaatt taaataagac
    20041 taaagttgaa ttagaaaaag taaagcaggt gtcagagtcc agaaaagatg cagttactaa
    20101 atctataaaa gaagttgaag gaaagattga taaagtaaat ataagtgcag aattaaaaca
    20161 aaaaatattt ctagcatatg aatacgagaa agattacaac aacgtattgg aagaaaaaaa
    20221 tcaaaagcta aataaactag aagaaatact caaagagaca gaaaatataa atttaaaagt
    20281 tagatatatt gataaagata agaatgatgt aaatcgtaat ttagaaaatt tatcacttca
    20341 cttggatgtt cttcttaaaa aatgtcctgg taagagtgct gatttacttt taaaatctga
    20401 atatgttact gaattaagaa gtaaagtaaa taatactaaa gaaaatgaaa ttaagaaaag
    20461 cagtatacaa gatgaattaa agataatact tgaaagtaag tttaatactg aaagggaagt
    20521 aaatttacta aatgaaaaac ttgaaaataa tagaaagaat agagatgacc tagaaaaaga
    20581 attagaagaa ctaaagtatt taaatttagc ctctgaactt agacgtgaat taaaagaaaa
    20641 tatgccttgt ccagtttgtg ggtcaaaaca tcatgaaaat cataatataa ctaagtatga
    20701 tgaaaatata tcttttgtca aagaaaaact ggagaaatta gaaaaagaaa aaataagtat
    20761 aagaaacaat atagaggaat taaatgctaa agtaagtggg tatttatcta tagaaaaaat
    20821 gaagactaaa gaacttgaag atgtaaaagg aaaactaggg gggattccat ctagtcaatt
    20881 attaaaaaaa cttgatgaag aacaaagaaa acttgcattg ttaaaatcta atattcagga
    20941 gtgggagaaa gaaaaagaga gtactgaaaa taaagtaaca ttagctaaag aagaaaaaaa
    21001 taaaattgaa aaagaagaat taaaaataag agagagtctg aataattata agaaattaac
    21061 aagagattta aacatagaaa tagaaggttt agaaaataaa tgtaaaaaac ttaaacagga
    21121 atacctagga ttaaagacga ttactaaagt ctctaatcta ttgtcaaaag taaaagaaat
    21181 aagggagaat gaaaaagaat tagaattact aagtactggg cattcaaatt tattaaaaaa
    21241 tagagactca ctagatatta aaataagaga aaatgagagt aaactacatg aaatagagat
    21301 agaattaata aaggctagag aattatatgt agaaaagaaa ttgagtagag ataataagta
    21361 taaagaagtt attaacataa cgaaaggtga tttagctaaa aatcttttac ataatgttga
    21421 agaaaatata tgtaagatat tagaacaaga agaatcaagt aagaaaaaat tggaagagca
    21481 aagattagag tatgaaaaaa acattgctga aaagcacaat atagatggta gacttaaaac
    21541 tgctaaggaa caatataaag accaaaaatc aacactaaat aaactattgg cagaaaataa
    21601 atttgaaagt atatatgcag taaaaagagc tttattagat actgatgaag taaaaaaatt
    21661 gattgaagaa atactagagc atgaagaaga acaaaagtta ttatcattta aaataaaatc
    21721 atcaaaagaa aaattaaatg gaagaagcat aaagaaggag tactttgaac agttaaaaga
    21781 tgaaatttat aatttgaaag tagaaatagg aaatatatcc aaagatattg gagctaatca
    21841 aaatcagtta ataacactaa aagactcttt agataagata aatgatttta ataaacaact
    21901 taaggtagtt gaacacaatg tggacttatt ggaagaatta gataaatgtg tgcaaggaaa
    21961 taaatttgta gaatatgttt ctacaaacca attaaaatat atagcattgg aagcatcaaa
    22021 acgattggat ggaataacaa aaggaagata tgcacttgaa attgactcaa cactaaactt
    22081 tgtaatgaga gataacttta atggaggaga aagaagaagc attgatactc tatctggtgg
    22141 agagacattc ttgacatctc tatcattagc acttgctctt tcatctcaaa tacaattaaa
    22201 gggaagtgca ccattagaat ttttcttttt agatgaaggt tttggttcat tagatagtga
    22261 acttttagaa attgttatag aatccttgga aagattgcat agtaataatc taagtgtggg
    22321 tataataagt catgtcgagg aacttaaaaa tagagttcct gttaagctat tagtttcatc
    22381 tagtgaggct ggaataggtt caaaagtaaa aattgaatat agttagaaaa tatatgttaa
    22441 ttgaatatat tatctaatat ttccaaataa tatgtaattg tgatataata aaaactaata
    22501 ttaaagttat ttataattaa tattaatata aaaacatgta agtaggagtg tggtaagtgt
    22561 tggaatcgcc caataatttg attcagatta tttttttaat agtattactt atagggtctg
    22621 catttttctc agcatctgaa acggccttaa tgtcgttgag taaaatcaga atcagatata
    22681 tgcaagatga aggagttaaa ggagctaagt tagtaagttc attaatagaa aatccaaata
    22741 agcttttaag ttctatattg gttggaaata acgtcgtaaa tatagcagca acatccatat
    22801 caacatcttt gtttatagga ttaatgggag aaaaaggagt ggcacttgct acagctgtta
    22861 tgacagtatt agtattaata tttggtgaga ttactccaaa aacaatagca gcaaataatt
    22921 cagaaaaggt ttctctatta gtatctaaac ctataaaagc aattatattt atattaagac
    22981 caatagtatg gatatttaat ataattacaa atattatatt taaattattt ggtataacaa
    23041 ataaaggagc taaatcattc ataactgaag aagagctaaa aactatggta aatgtaagtc
    23101 atgaagaagg tgtccttgaa atggaagaga gagaaatcat aaataatgtt tttgaatttg
    23161 gagatatgca agctaaaaat gcaatggtac aaagaataga tatggtagct atagatatgg
    23221 aagatagtta tgatgagata atacaggtat ttaaaactga aaaattaagt agaatgcctg
    23281 tgtatgaaga aactatagat gatatcgtag gaatacttaa tataaaagat attatatttt
    23341 tatctgatga agaaatagag tcatttgata ttaaaaatta tatgagagaa ccttttttca
    23401 cgtatgagtt caaaaagata acacaacttc ttgaagagat gaaacttgaa aaaagtcaga
    23461 tggctatagt tgtagatgag tatggtggaa catctggact tttaactata gaagatttag
    23521 tagaagtcat tgttggagat atagaggatg aatatgatga agaagaggat gaaatacaag
    23581 ttataaaaga agatgagtat attgtagatg gaagtactaa aattggtgat gttaatgaac
    23641 ttattggtgt aaacttggaa tctgaggagt ttgattccat aggaggtttt ataattggac
    23701 acctaagcag attgccagaa gaaaatgaag taattgaagt tgataatata agattttgta
    23761 tagaaagtat agaaaaaaat agaattaaaa aaataagaat atatacataa tgtaataatg
    23821 ttcttaaatt tattagaagt gtataaatat aaaagatatc ttttatattt atacacttct
    23881 ttttattttg tattcaaata aaactagtat gaaatggaca aaataaaaat ataaattaga
    23941 agaaaggaga tttttaagat gagcatacta gaaaataatt ttttatacaa attaaaaaac
    24001 aacactatct ttttttgtat atatacattg ttatttattt ttatttacaa agcgtttcca
    24061 tacatagctc cattttttct aggtggtata atagcactta tgattaatcc tatatcacaa
    24121 aagttagaaa ataagtttcg tataaataaa ggtatctcta ctcttgttct aagttttctt
    24181 gcagtggcta tagtcagtac agttactaca ataatagtaa taaattcaat gaaagaatta
    24241 atgggatttt taaataatat atctgctaat cctgaggata taagtaatac tattatgtat
    24301 tttttaaata aaataaatga ctttatgaaa tcatttcaag aaatagccaa ttttgatgta
    24361 gaacaattag taaacaaatt cagtggtgaa gtaatgcaaa ttacaaaaaa tcttcttact
    24421 agtatacttg gattggctac ttctattcca tatattataa tatttataat taccttgttt
    24481 attgctacat actttatagc aaaagacctt gataagattg aaaatagttt ttataatatg
    24541 tttactgttg atgttagaaa gaaggtaaaa aacgtaaaga aagaggcagg gctttcactt
    24601 gttggatata taagggccta tacaatactt atggctataa cattttttgc aatctgggga
    24661 agttttgctt tatttggatt gaaatacggt ctaatagtag ggtttgtagg agctttaatg
    24721 gatttaattc cattcctagg tataataaca atatatcttc cagtaattgt ttattatttt
    24781 cttataaaaa attattttat agctataagt atgactgtga tattttttgt tttgtctttg
    24841 attagagaaa tacttgaacc taaactagta tcagtaaatg ttggactaaa tccattagct
    24901 accctagcag cgatttttat tggaatccaa gtaaaaggaa taattggagt aattttttgt
    24961 ttgggtttgg tatgtatgca tgatatactt aagaaggtgg atatttttta attataataa
    25021 ttgatagatt tttttaaaaa taaaatttta ttcacaggta aaaaaatatt aatcttatta
    25081 agaaagaggg tatatacgtg aagcaaaaac tagtggaaag atttttaaaa tatgtatcat
    25141 ttgatacaac atctaattct cagtgtgaga actgtccatc ttcagaaggt caaagagttt
    25201 tagctaagta tatagttgaa gagctaaaaa caatgggtgt tgatgatgtg agtttagatg
    25261 aaaatagtta tataatggct actttaaaag gaaatactga tggtgtggat actataggat
    25321 tcatatcaca tttagataca attgaagatg ttagtggaaa agatattaaa ccaagaataa
    25381 tagaaaatta tgatggaaaa gacatagttt taaatgaagc gttaaatgtt attacgtatg
    25441 taaaggattc tccagagttg gaagaattta aaggtgacga tttaatagtc actgatggaa
    25501 caactctact tgggtctgat gataaagctg gtatagctga gatagtgact gcaatagagt
    25561 atctaataaa tcatccagaa attaagcatg gagatataaa aataggattt acaccagatg
    25621 aagaaattgg tagaggtgct gatttatttg atgttgaaaa atttggagca aaatatgcat
    25681 atactttaga tggaggaata gttggagaac ttgaatgtga aaattttaat gctgcaaatg
    25741 caactattac tatacatggt agaaatgttc atccaggttc agctaaaaat aaaatggtaa
    25801 atgctataca tatagctgct gaaatatcag aaatgttccc agcagatgaa agaccagaaa
    25861 caacagaagg atatgaagga ttttggcatt taaattctat aggtggaaat gtcgagaatg
    25921 taagtatggc ttatattatt agagaccatt gtagagaaaa atttgaaaat agaaaatcta
    25981 ttatgataga gaatatagaa aaaataaata agaaatacga taatagagtg gaattggatt
    26041 taaaagattc ttattacaat atgaaagaaa agattgagcc agttatgttt atagttgata
    26101 tagctaaaga agctatggag gaattaggta taaaaccacg tttagttcct gtaagaggtg
    26161 gtactgatgg agcaagatta tcttttaatg gattaccttg tccaaatata tttactggtg
    26221 gattaaactt ccatgggaaa aatgagtgta taccagttag ttctatggag aaagctacta
    26281 aactaattgt aagaatagct gaaaaatatg ctgaaagagt ttagttaaaa agtatttaaa
    26341 aattaagcat ttaaagttat aatagctata tcattcttta taagtcaagc tgattataag
    26401 cttgtgttgt atttaaaatg gtatagctat ttttgtaatt atttttataa aagataatta
    26461 tttttagttt agggtatcaa taaaaagtat ggatatcaat aggtattaac atttaaaagg
    26521 gggaattgta ttgaaaatta aatctaaaaa aataatagca tttgcacttt cacttgggat
    26581 tatgttgcca agttgtgtat atgcagacac tattagtaaa aatcaaaatg cacaggtaga
    26641 tatgaacaat tatcttcaag gtagaaaatc tccaaaggag gaaaaactta ttggtgaaga
    26701 tagatttgat acagcgataa aaatatctca aagtggttgg aataatggtt cagaaagggt
    26761 gtttctagtt aactcaaatt cattgccaga tgcattggct tcaactcctt tggcaagtaa
    26821 attggatgca ccaatactgc ttacaaataa aaatagtata ccatataatg taacagagga
    26881 aataaaaagg cttaatccag cagaagttat tttaattgga agtgaaggag ctatttcatc
    26941 aagtgtaaaa gaatctcttg aagatatgga agtattagtc agtagaatcg gtggagcaga
    27001 tagagaagaa acatctttac ttcttactag acagctagat gatactggtg atttaggtgt
    27061 ctcaaaagtg gcagtggtta atgggtataa tggactggca gatgcaactt caatatcaag
    27121 cccagctgca agtgataata cagctataat atatacaggt aaggatagca taagaagtga
    27181 ggcaaagaat tttattacac aaaactcaac taagacatac atagtaggtg gggagtacag
    27241 tataagtaaa aaacttgaag gacagttagt aaactcagaa agactagcag gaacagatag
    27301 aaaagatact aatgcgaaag ttttagaaaa gttttatgga aaatcaagta aggttaataa
    27361 tatgtatttt gcaaaagatg gaagtggtag agaagctgat ttagttgatg ggcttgctgc
    27421 tggagtatta gcatcaaaaa caaagtcacc tgtagtactt gcaagtggaa gtttaagtag
    27481 tgcacagaaa agttttataa aaaaagtaaa ggctgataaa tttgtacaag ttggtggagg
    27541 taaaaatagt aaaccatatg cagaagcatt agccttacag taatattgtg taaatcaaaa
    27601 ttaatatata ataatagcaa gtaaaccaag ttgcacttca atatatataa taaaataagc
    27661 aaactaagtt atatttcagt ataatatata ataaaataag taaactaagt tatatttcag
    27721 tataatatat aatgaaataa gtaaactaag ttatatttca gtataatata taatgaaata
    27781 agtaaactaa gttatactcc aatataatat ataatagaaa caagtaaact aagttatatt
    27841 tcaatatagc atataataaa acaagtaaac cagattctat ttaattagaa gtttaaggta
    27901 ttgtacttaa acttctaatt gagatagaaa taaaatggtt tacttgtttt tattatgagt
    27961 ttaataaatt aaagcttatt ttatttttat taaaaattta ctaatcatta atatttatta
    28021 tatttccagt attgatgtca attaagttta tatcaagttc aagctcatcc tcatcatcag
    28081 tttttatgat atctataatt gcgacagaat ggcttccatc ttttgggata gaagtacttc
    28141 ctggatttat tactattaaa ttatcatcca tgtatagttt ttttacatga gtatgtccta
    28201 aaactaatat gtcaccaccc attttctttg ctttgtcaat aatttcttct tctgattcta
    28261 tataaccatg attcaatata attctaattt caccaaattg gctcatgaca taaggactct
    28321 gaataggatg ttctataacc atctggtcaa catctgcatc acagttccct tttacaatca
    28381 caatgttttc taatttattt aatgtctcaa taaatttttt aggattatat ccttctggaa
    28441 tatcatttct aggtccatga tataagacat ctccaccatg taataaaaca tcacaatcag
    28501 ataatacatt taacgctttt tcaaagtaaa gtaagctacc atgagtatca ctcattattc
    28561 ctattttcat attaaaaatc ctcctaagta cagtctataa aaatttttca gatactctat
    28621 gccaaaactc atagtttgac attctaagta attttatttt tgcatcagat atactaactt
    28681 ttatattttc gatttgtcta aatctgtgct caactccatc aacgacaatc aatacagaat
    28741 cttcaaatct atattctggt gcaatcttta taacagattc atttgaacat attatacttg
    28801 atgtaaagca cctatatgca ttggtattta tcggatgtaa aggtgtaatc tgcataagtt
    28861 caagatttat atcaacaata ctacctccag cagaatagtt ataggctgtt gaacctgtgg
    28921 aagtagaaat aatcatacca tctccactaa aattttgtat atgtttatta tcaaggctta
    28981 aatttaggtg tatagtccta gacttgtctc ctcttataac aacctcattt acagcaagca
    29041 tattagaacc actagtagtt gtatatactt ccgcattaag aagtgacatt tcttgaataa
    29101 tataatcttt ttttgtataa gcttcaataa agctatcaat cttatctggt aaaatatcag
    29161 gaaaaaaccc cagatgacct gtatttattc ccattatggg aatctcagga aaatcgaaat
    29221 ctctaactgt tcttaaaaaa gagccatcac caccaattga tataataagc tctgtgtctg
    29281 gataaatatc tgaatacact tcaaagccag cattgataag ttttctagtt aagagttctt
    29341 tagtctcaag ggacttattt aattggtttg tatttatagt tataattctt ttcatatatt
    29401 cacctcttca tactttgtat tataacatag ttttataatt cttaatttat aaatttataa
    29461 atgacctttg tagtgaatgt gttaaaatat gtataggtgg gtataaaaaa atgcataaga
    29521 ggtgaagatg tgtttagcat aaggaatatc acaaaaaaat taggaaaatt caagttaaat
    29581 aatataaact tagagttaaa ggaaggggat attgttggga ttataggacc aaatggttcg
    29641 ggaaaaacga ctttaataaa aattataatg gggattattg atgcagatga aggtgaaatt
    29701 gaactttgta atgaaactat tgaaaattct ccaataagct ttaaaaacaa tattggtttt
    29761 gtatatgatt ctttacaatt ttatccacat ttaaaggtta aggaatttag aaaaatagtt
    29821 tctttatttt ataagaattt tgatagagaa aaatttgatg aataccttaa taagtttgac
    29881 atagaagaaa atatgcatat tgaaaattta tctaaaggtc aatctgagaa gcttatgtta
    29941 tcaagcgcac ttagtcataa tgctaagtta ttgattttgg atgaaccaac tgctggtata
    30001 gacccgattg taagaactga aataatgcag tacttacaag attttgtgaa aaatggaagt
    30061 agtagtgtaa taatttctac tcataatact gataatttaa ttaaaattgc tgattatctt
    30121 gtttttataa atagaggaaa tcagattttt actgttaaga aagaattaat agaacaagaa
    30181 tataagataa ttagggcaaa taaagcagag ttagaagcaa ttaaagaaag tatagttggt
    30241 gttaaagagt ataaatatta taatgaggca cttgttaaag ttggagatag cttgaaagta
    30301 aaaagcctat tgatagaaat tgataagcat aaggtcaaaa atcctactat agaagaacta
    30361 atgtattatt atgtaaatga ggtgagatga tgttcaattt aataagaaaa gatttaataa
    30421 tagggattag ttcagatggt atccgtaatt taaagtacat attgctattt tttgtgtttt
    30481 attttttcct taattcaatt tcatattata cagtaagtat tgttgttagt tatttgatat
    30541 ttataaatac atttgagtgt gattatgaaa atgattcaag gatttttata aggagtatgc
    30601 cagttagtat agaagatata gtttactcaa aatatttatt aggtgtagga ctaataattt
    30661 ctgtaacaat aattgtgtcc ttactaagta aattgacatc actagtgttc tttagaaata
    30721 tggttttaaa tgatgtattt ttttctgtaa atatattttt agcaattttg acgattttac
    30781 tgcctttaat ttttaagttt ggatatggaa aaatgaaagt ttgtggtttt atagtaagta
    30841 ttttaattta ctttgtatat ggaagtcttt tgaagatgat tagtatgatt gtatatcaag
    30901 taaagcattt taattatagt aaagttggag gagtatatct ttcaaattat gtaactgata
    30961 tagctaatac taagtatata aatttatata gtatgacatt tttaacaata ataattttta
    31021 taatatcaat gtatttttct attaagattt caaaaaagaa taagtttaat tattaaaatt
    31081 ttaattaata ttatagcaca atagcacaaa atataaggag actaaaaatg aagaagttta
    31141 taaaagtttc attttttatt ttggggattt ttacactatt catagctata aatgaattag
    31201 tatatagaga tatggtaagt gtcaaagatt atgaaataaa tcatttagag gaaattgttt
    31261 ttgattttga tagcaggaga agtagagata tcggtactat tgtaagattt aaaataagca
    31321 ataatagtaa atatagttat aaattaaaca gtgctaaaat gaagtttgaa aattgtgtgg
    31381 aaaataaaaa gggaatgaat aagtgttctg catatgtaaa tgtagattta tttaatgaaa
    31441 aaaattctat aactgaaagg actctgaaat atggaataaa accaaataat caaggttatg
    31501 ttgattttgt aattccaaaa ggactaaatt ttgattatag gtactttaat gaatctggta
    31561 tgagtgtaga atataaagga gaatatattg tcaatattcc aatggcaaaa ggactttatc
    31621 tagtagttgg aaaaaataat gatacatgga atgctaatat tatggaataa tttgaaaaat
    31681 aaatcaatta tagatataat taagaataat atgaaattta taaaaattca gattaggagg
    31741 ggtatttaat gtcaataagt aatgtaagag agtattttaa acaatttggc aaggaagaca
    31801 gtatattaga atttgaacaa tctagtgcta ctgtggaact tgcagctgaa gcagctgggg
    31861 ttattccagc aagaatagct aagacactct catttaaaat aggagatgat gcaattttaa
    31921 ttgtgacagc tggtgatgct aagattgata ataagaagta taaggctgaa tttaattgta
    31981 aggctaaaat gttgacacca gaagaagtct tggagtttac tggacatgct attggtggag
    32041 tctgtccatt tggtttaaaa aattctataa aagtctattt agatgattca atgaagagat
    32101 ttgatacagt atttcctgca tgtggcagta gtaactctgc aatagaactt acatgtgaag
    32161 aaatggagaa gttttctaag agtgaaaaat gggtagatgt ttgtaagaat tggtaaaaaa
    32221 atatagtaaa ctatagtagg aattagtaaa aaactacctc tgtatacaat ctatacagag
    32281 gtagtttttt gtgtaaatat ttataaatct aagaggaaaa tctaatttaa actaataatc
    32341 caaaataaag ttaaaaaatt ctgatttttt ttcgaaacaa taaaaaaatg acaaaaaagt
    32401 ggaaaaaatg taataaatat tgttaaaaaa ataattagaa attattgaaa aattatcctt
    32461 tgagtgttac tattatagat gtaagatatt taaaaataaa aaatagtcag ataaaaatac
    32521 gattatttag ctctattaaa ataattttta tacgataaaa atcttctgta catggctaaa
    32581 aaacagatgt acagacaata tttaatgttt aatataccct aatataaata tcgtaaacaa
    32641 attattttat ctgtgaccag tgtgaaagaa atcttattct aacttgaaat ttcacaaaat
    32701 tccaaaaagc gagatttttt ttaagtatag ttgattttaa attaacaatt tatgattaaa
    32761 ttaatgtcat aattggttag tataatcaca tataaatata gagcgtagtt tgattaaggt
    32821 tataaatttc tcgacgtata ttcaaatacc ttattataga tgttgccgag attttaatta
    32881 ataaatgaaa ataaaatatt tataaaatac tgaggaggct attatggatt taaattctaa
    32941 aaaatatcag atgcttaaag agctatatgt aagcttcgct gaaaatgaag ttaaaccttt
    33001 agcaacagaa cttgatgaag aagaaagatt tccttatgaa acagtggaaa aaatggcaaa
    33061 agcaggaatg atgggtatac catatccaaa agaatatggt ggagaaggtg gagacactgt
    33121 aggatatata atggcagttg aagaattgtc tagagtttgt ggtactacag gagttatatt
    33181 atcagctcat acatctcttg gctcatggcc tatatatcaa tatggtaatg aagaacaaaa
    33241 acaaaaattc ttaagaccac tagcaagtgg agataaatta ggagcatttg gtcttactga
    33301 gcctaatgct ggtacagatg cgtctggcca acaaacaact gctgttttag acggggatga
    33361 atacatactt aatggctcaa aaatatttat aacaaatgca atagctggtg acatatatgt
    33421 agtaatggca atgactgata aatctaaggg gaacaaagga atatcagcat ttatagttga
    33481 aaaaggaact cctgggttta gctttggagt taaagaaaag aaaatgggta taagaggttc
    33541 agctactagt gaattaatat ttgaggattg cagaatacct aaagaaaatt tacttggaaa
    33601 agaaggtcaa ggatttaaga tagcaatgtc tactcttgat ggtggtagaa ttggtatagc
    33661 tgcacaagct ttaggtttag cacaaggtgc tcttgatgaa actgttaaat atgtaaaaga
    33721 aagagtacaa tttggtagac cattatcaaa attccaaaat acacaattcc aattagctga
    33781 tatggaagtt aaagtacaag cggctagaca ccttgtatat caagcagcta taaataaaga
    33841 cttaggaaaa ccttatggag tagaagcagc aatggcaaaa ttatttgcag ctgaaacagc
    33901 tatggaagtt actacgaaag ctgtacaact tcatggagga tatggataca ctcgtgacta
    33961 tccagtagaa agaatgatga gagatgctaa gataactgaa atatatgaag gaactagtga
    34021 agttcaaaga atggttattt caggaaaatt attaaaatag ataaatatta aaatatacac
    34081 aataggtcga tattaaaata gatatggagg aaggatttat gaatatagtc gtttgtataa
    34141 aacaagttcc agatacaaca gaagttaaac tagatcctaa tacaggtact ttaattagag
    34201 atggagtacc aagtataata aaccctgatg ataaagcagg tttagaagaa gctataaaat
    34261 taaaagaaga aatgggtgct catgtaactg ttataacaat gggacctcct caagcagata
    34321 tggctttaaa agaagcttta gcaatgggtg cagatagagg tatattatta acagatagag
    34381 catttgcagg tgctgatact tgggcaactt catcagcatt agcaggagca ttaaaaaata
    34441 tagattttga tattataata gctggaagac aggcgataga tggagatact gcacaagttg
    34501 gacctcaaat agctgaacat ttaaatcttc catcaataac atatgctgaa gaaataaaaa
    34561 ctgaaggtga atatgtatta gtaaaaagac aatttgaaga ttgttgccat gacttaaaag
    34621 ttaaaatgcc atgccttata acaactctta aagatatgaa cacaccaaga tacatgaaag
    34681 ttggaagaat atatgatgct ttcgaaaatg atgtagtaga aacatggact gtaaaagata
    34741 tagaagttga cccttctaat ttaggtctta aaggttctcc aactagtgta tttaaatcat
    34801 ttacaaaatc agttaaacca gctggtacaa tatacaatga agatgcgaaa acatcagctg
    34861 gaattatcat agataaatta aaagagaagt atatcatata atttaagggg ggataaagaa
    34921 tgggtaacgt tttagtagta atagaacaaa gagaaaatgt aattcaaact gtttctttag
    34981 aattactagg aaaggctaca gaaatagcaa aagattatga tacaaaagtt tctgcattac
    35041 ttttaggtag taaggtagaa ggtttaatag atacattagc acactatggt gcagatgagg
    35101 taatagtagt agatgatgaa gctttagcag tgtatacaac tgaaccatat acaaaagcag
    35161 cttatgaagc aataaaagca gctgacccta tagttgtatt atttggtgca acttcaatag
    35221 gtagagattt agctcctaga gtttctgcta gaatacatac aggtcttact gctgactgta
    35281 caggtcttgc agtagctgaa gatacaaaat tattattaat gacaagacct gcctttggtg
    35341 gaaatataat ggcaacaata gtttgtaaag atttcagacc tcaaatgtct acagttagac
    35401 caggggttat gaagaaaaat gaacctgatg aaactaaaga agctgtaatt aaccgtttca
    35461 aggtagaatt taatgatgct gataaattag ttcaagttgt acaagtaata aaagaagcta
    35521 aaaaacaagt taaaatagaa gatgctaaga tattagtttc tgctggacgt ggaatgggtg
    35581 gaaaagaaaa cttagacata ctttatgaat tagctgaaat tataggtgga gaagtttctg
    35641 gttctcgtgc cactatagat gcaggttggt tagataaagc aagacaagtt ggtcaaactg
    35701 gtaaaactgt aagaccagac ctttatatag catgtggtat atctggagca atacaacata
    35761 tagctggtat ggaagatgct gagtttatag ttgctataaa taaaaatcca gaagctccaa
    35821 tatttaaata tgctgatgtt ggtatagttg gagatgttca taaagtgctt ccagaactta
    35881 tcagtcagtt aagtgttgca aaagaaaaag gtgaagtttt agctaactaa tttcttgggg
    35941 agggtattat gagtacaagt gatgttaaag tttatgagaa tgtagctgtt gaagtagatg
    36001 gaaatatatg tacagtgaaa atgaatagac ctaaagccct taatgcaata aattcaaaga
    36061 ctttagaaga actttatgaa gtatttgtag atattaataa tgatgaaact attgatgttg
    36121 taatattgac aggggaagga aaggcatttg tagctggagc agatattgca tacatgaaag
    36181 atttagatgc tgtagctgct aaagatttta gtatcttagg agcaaaagct tttggagaaa
    36241 tagaaaatag taaaaaagta gtgatagctg ctgtaaatgg atttgcttta ggtggaggat
    36301 gtgaacttgc aatggcatgt gatataagaa ttgcatctgc taaagctaaa tttggtcaac
    36361 cagaagtaac tcttggaata actccaggat atggaggaac tcaaagactt acaagattgg
    36421 ttggaatggc aaaagcaaaa gaattaatct ttacaggtca agttataaaa gctgatgaag
    36481 ctgaaaaaat agggctagta aatagagtcg ttgaaccaga cattttaata gaagaagttg
    36541 agaaattagc taagataata gctaaaaatg ctcagcttgc agttagatac tctaaagaag
    36601 caatacaact tggtgctcaa actgatataa atacgggaat agatatagaa tctaatttat
    36661 ttggtctttg tttttcaact agagaccaaa aagaaggaat gtcagctttc gttgaaaaga
    36721 gagaagctaa ctttataaaa gggtaaaaat ctaattaaaa atatatttgc tgttaactag
    36781 attaaatagt attttaatct agttaacaga atataaatac taaaataaca ggaggttata
    36841 actatgaaat tagctgtaat aggtagtgga actatgggaa gtggtattgt acaaactttt
    36901 gcaagttgtg gacatgatgt atgtttaaag agtagaactc aaggtgctat agataaatgt
    36961 ttagctttat tagataaaaa tttaactaag ttagttacta agggaaaaat ggatgaagct
    37021 acaaaagcag aaatattaag tcatgttagt tcaactacta attatgaaga tttaaaagat
    37081 atggatttaa taatagaagc atctgtagaa gacatgaata taaagaaaga tgttttcaag
    37141 ttactagatg aattatgtaa agaagatact atcttggcaa caaatacttc atcattatct
    37201 ataacagaaa tagcttcttc tactaagaga ccagataaag ttataggaat gcatttcttt
    37261 aatccagttc ctatgatgaa attagttgaa gttataagtg gtcagttaac atcaaaagtt
    37321 acttttgata cagtatttga attatctaag agtatcaata aagtaccagt agatgtatct
    37381 gaatctcctg gatttgtagt aaatagaata cttataccta tgataaatga agctgttggt
    37441 atatatgcag atggtgttgc aagtaaagaa gaaatagatg aagctatgaa attaggagca
    37501 aaccatccaa tgggaccact agcattaggt gatttaatcg gattagatgt tgttttagct
    37561 ataatgaacg ttttatatac tgagtttgga gatactaaat atagacctca tccactttta
    37621 gctaaaatgg ttagagctaa tcaattagga agaaaaacta agataggatt ctatgattat
    37681 aataaataag aatttgggaa ttaaaagttt agataaaatt gtttaaaaaa caatttcgga
    37741 tatatgaaaa atctaattta atgggggtaa tgaatatgag agaagtagta attgccagtg
    37801 cagctagaac agcagtagga agttttggag gagcatttaa atcagtttca gcggtagagt
    37861 taggggtaac agcagctaaa gaagctataa aaagagctaa cataactcca gatatgatag
    37921 atgaatctct tttaggggga gtacttacag caggtcttgg acaaaatata gcaagacaaa
    37981 tagcattagg agcaggaata ccagtagaaa aaccagctat gactataaat atagtttgtg
    38041 gttctggatt aagatctgtt tcaatggcat ctcaacttat agcattaggt gatgctgata
    38101 taatgttagt tggtggagct gaaaatatga gtatgtctcc ttatttagta ccaagtgcga
    38161 gatatggtgc aagaatgggt gatgctgctt ttgttgattc aatgataaaa gatggattat
    38221 cagacatatt taataactat cacatgggta ttactgctga aaacatagca gagcaatgga
    38281 atataactag agaagaacaa gatgaattag ctcttgcaag tcaaaataaa gctgaaaaag
    38341 ctcaagctga aggaaaattt gatgaagaaa tagttcctgt tgttataaaa ggaagaaaag
    38401 gtgacactgt agtagataaa gatgaatata ttaagcctgg cactacaatg gagaaacttg
    38461 ctaagttaag acctgcattt aaaaaagatg gaacagttac tgctggtaat gcatcaggaa
    38521 taaatgatgg tgctgctatg ctagtagtaa tggctaaaga aaaagctgaa gaactaggaa
    38581 tagagcctct tgcaactata gtttcttatg gaacagctgg tgttgaccct aaaataatgg
    38641 gatatggacc agttccagca actaaaaaag ctttagaagc tgctaatatg actattgaag
    38701 atatagattt agttgaagct aatgaggcat ttgctgccca atctgtagct gtaataagag
    38761 acttaaatat agatatgaat aaagttaatg ttaatggtgg agcaatagct ataggacatc
    38821 caataggatg ctcaggagca agaatactta ctacactttt atatgaaatg aagagaagag
    38881 atgctaaaac tggtcttgct acactttgta taggtggtgg aatgggaact actttaatag
    38941 ttaagagata gttttagatt ataatattta caaattaaat atttaattat gaatttaacc
    39001 tgtaagaata actatttgtt attcttacag gtttttatag ttaaaaataa ttattatcta
    39061 ttaaacaaaa atagtgtaaa atatataata tcatgatttt gaagatataa aaagtaggaa
    39121 gatataaaag aaagtaggta aaagtttgtt taaaaaagag aatcaaagat ataatcttat
    39181 atcgtataca aatgaagaag aaatgacttt aaaagaagtt ttattggaca agctaaattt
    39241 ctcagttagg tcattatcaa aaatgaagag ggaaaagagt gttttagtaa atggagtata
    39301 taaaaaacca agtttaaagg tgtatagtgg tgatttaata gaagtaaaaa tagacgagga
    39361 aaaagcaaat tttgaacctc aagatttaaa tttacagata atttatgatg attttgatat
    39421 aattatggtg aataaacctc catttatggt agttcaccca acaaaaagcc actatgataa
    39481 aacaatagca aatggtatta gttactatat agataatcaa aaagaaaacg taaaaataag
    39541 atttgtaaat aggttagata tgaatacttc agggttagtt atagtagcaa aaaatgctta
    39601 tgcacatcat actttatcta cagcaatgag tgaaaataaa gttgaaaaaa agtatataac
    39661 agtagttgat ggaattataa aagaaaatga gggaactata gatgagccaa tttatagacc
    39721 tacagaagat tcaataaaga ggataataga tgaaagagga cagtcatctg ttactcacta
    39781 taaagtaata gaaagactag aaaatgcaac tgtattagaa gtaagcttag aaactggtag
    39841 aacacatcaa ataagagtac atatggctca tataggtcat ggaataatag gtgatgagtt
    39901 gtatggttat gtagatgaag agctaataaa taggcaagca cttcatgcat acaagctaga
    39961 gtttgaacaa ccaagaacaa aagaaaaatt gaaatttaaa gcagatatac cagaggatat
    40021 gaaagagtta atatcgaaat taagataatg gggtgatata tatgataata cataaattta
    40081 taatacatgt tttggacaaa aatagtgatg ttccaatatt aaatgacttt gaaggcaaag
    40141 ttaatcaaga agtagatggt tttttccaga aagctataaa aagaattgca aaagatgagg
    40201 atttaagaaa aggtgttttt aaagattata atgataattt aattaaaaac tgttgtgaac
    40261 aaataatata tgatgaaagt acttttttga aaaattctaa agaaattgca tcttacttgt
    40321 ttgacgttat gaaaattaat gctgcactag aatcttgtga tttggcaatt tgcttataca
    40381 ctattaaaga tgaaaagagt gtagcaatac tgaaattaga ttataaaaag ttgtacactc
    40441 attcaattga atttgtggat gataaattta atattcaaat ggtttcaaat gaaattggta
    40501 tcccagagac tttaagacaa aagcaaggag ctttgattag tctaagtggt ataaatgatg
    40561 agtttcatct aaggctttta gataaggatg ctgaaaaaga agggtcagaa tctaagtttg
    40621 taacagaatt tttaaatgct aaaaaaatag atgatgataa gtacaagacc aaggtattta
    40681 aaaatacagc tgaaaattgg ataactaatg ctcttagtaa tgatataaag caagctgaag
    40741 atgtaagaag tatattaaat tatacactga aggaaaaaca tgaagttgat ataaatgact
    40801 ttgttgataa ttcaattaaa gatgatgagt taaaggatag ctttaaagag catatggaag
    40861 aaaaaggtct tgatgaaagt tttagtatag ataaaaaatg ggttgagaaa aagcttaaaa
    40921 aaagaagtat aaaaacggat aatggttttg acataaaagg gaatctaact gattttgaag
    40981 acccaatgaa gtatactgta aagcaaaatc aagatggaac tatagatata ataataaaga
    41041 atgttacatt ttatgaagaa aagtaattta tatacttagt atataaatta aatataagag
    41101 cgtgtatttt atatattgta aataaatgta atctagtctg tgcgaactct aatataattt
    41161 attatgtaga agtttacaca gactatttat atttgtagac aaaacgatac tatttgtttt
    41221 cttcgatata tttacatata tcaccaatac atttaaagtt ctcagcttcc tcgtctggta
    41281 tttctattcc aaattcatct tcaagggcca ttataatttc aacagcatct aatgaatcag
    41341 cttctaagtc gtccattaaa gatgcttcca tagttatctc atctaaattg tctaccccta
    41401 attgttctgc tattatttct tttattttct caaacatttt aagcctccta aagcagtttt
    41461 aattaatttt aatgttagtt taatataata tcaagaattt ttcaatatgg aatctataaa
    41521 aaataataaa attttataaa tgtagtaata aagtattatt tgatgaataa actttattga
    41581 taacaaatat aacttaggag gaaatgctat gaaatatgta ggactattac taacttcagt
    41641 aggaatgttt ttacttatag cagtaaattt ttattataat tcaataactt tagatatgca
    41701 acgtatagag gattatgtaa tggagaccaa tttaatcctt gaagatgtag ctgaaaagga
    41761 gagttatgta tctaatgaaa aagaagacta catatcaagg ttaatgcatg taaagaaagg
    41821 aatagaaaat tcaaaaacat ccttcttgat agaaagatat aaggagtaca aaataaaatc
    41881 aatagaaagt ttaatctaca ctatatcaga ggagaaaaaa gattatctgg atgaagttga
    41941 tagatacaat aaacttggtg aaaaagaaat aaataaacta atcaataaaa actttttaga
    42001 agtaacttat ctgtctatta ctacatatat ttaattaaag agacaaaact tagtctctta
    42061 atgattcaag gaggattagt tatgacaaaa ttagaagaca atatggaacg tttctttgga
    42121 ggatgcgaag gattttttgg taataaaatg ttgataataa tagttatagt attcttacta
    42181 ttatgcacag acattttaga agacttatta tgcgatgaca atatatggat atgggttata
    42241 ttaatagtat tgttattatt taacttcgat gatggttgtt gttgctaaaa aatattgatt
    42301 attaaatagg taaaaccagt aacttataca agttatggtt ttaccttttt tagttcaaat
    42361 taaaaaattt aaaaaaatag taaaaataca ttagcaaaat ggaaaccaaa tgcatagtat
    42421 atgttaggag cgaaaagctc aacaaaatat caacaggagg taacgtacaa tgttagatag
    42481 attctttgga gaagaaggat gttttggtgg aggaggatgg tggataatag tactattctt
    42541 cctattctta gcttttggag atagctgggc agaatttgac ataatggcat ggataccatt
    42601 cctaatagtt ttattaatac tttgctgctg tggtggatgc ttagaataag aacacagtta
    42661 ttaaaaaaag gagggctttg ttatgttaga tagatttttt ggagaagaag gatgctttgg
    42721 tggaggagga tggtggataa tagtactatt cttcctattc ttagcttttg aagattgctg
    42781 gagagacatt gacataatgt catggatacc tttcttaata ttattgctaa taacttgttc
    42841 atgtggtgga ttctttgatg gtgaagtagg ttgcggctgc taatacttaa atcattagaa
    42901 taaaaaaatg ctggtatttt ataccagcat ttttttattt tattttttaa tatgatttaa
    42961 attaagaatg aatattatta aatttgttga atatagggta taatataaaa tataatgtat
    43021 ttaaatgtac ttgcttttat ggtaaaataa aaacttatat aaatgtagtt aaaataggaa
    43081 ccttcaaaaa tttggttcag ttttagataa atttagtaaa ataaggagga tgaagatgaa
    43141 aggcaatata acgataaaag atgttgctaa acaagcagga gtgtcaatat ctactgtatc
    43201 tagagttata aatgattcaa aacctgtaac tgatgaagtc aaacaaaaag ttttagaggt
    43261 tataaaagag actggatata taccaaatcc acttgctaga agcttagtaa caaagaagag
    43321 tcaattaata ggggtaatag ttccagaagt ttcagattct tttgttaatg aggtgttaaa
    43381 tgggatagaa gaggttgcta aaatgtatga ctatgatatt cttttagcga atacatactc
    43441 tgataaggaa caagaactta agagtataaa tctattgaga gcaaaacaag tggaaggtat
    43501 agttatgatt tcatggatag ttgaacaaga acatatcaac tatatacaaa attgtggaat
    43561 accagcgaca tatataagta aaactgctag aaattatgat atatatacag taagtactag
    43621 caacgaagaa gctacttttg atatgacaga gcatcttata aagaaaggtc atgaaaagat
    43681 agcttttata atgacgagta aagatgatac tgttttagaa atggaaagac ttgctggtta
    43741 tgagaaagca ctttcaaata acaatataga attagacaag agtttgatta agtatggtgg
    43801 aactgattat gagagtggat acaatagtat gaaagaacta ttagatgatg gaataatacc
    43861 tcatgcggct tttgtaacag gtgatgaggc tgccataggt gctataaatg ctatatgtga
    43921 tgctggatat aaggttccag aagacatatc tgttgcagga tttaatgatg ttaagatagc
    43981 tagaatgtat agacctaaac ttactacagt atatcaacct ctatacgata tgggagcagt
    44041 agcaataaga atggttataa aattaataaa taaggaatta attgaaaata agaaaataga
    44101 attaccttat agaattgttg atagagaaag tgttacagaa agaaaaaaat aaaactatta
    44161 aagtcaatca ggtagtgcct aaggcactac ctgatttttt atgtcaataa tatcaaattt
    44221 aataatagat taactaaaaa taattatcta attacttaaa tagtttattt ttatctattc
    44281 atgagggtta gactttttag ttttcttaaa taaactttta gatttttttt gttgactacc
    44341 tggtgtattt tttggtgcag gtgaatttga cttaccttta gtaggtttag ccttcttagt
    44401 tttagctggt ttagtatctc tttggttttc tgcatctgag attttttcca ttatattatc
    44461 cagttttttg cgttgatttt catctaaaaa tgctttgaat tttgatacta cttcatctct
    44521 gccatctagg ttcttaccta tttttataag ttcctccata agttcatttt ctgattttcc
    44581 tttgtaacta tcagccatct tttctatctt atccttgtca atattttttt gtttagccat
    44641 tttttctaat gactctgtat ctaatttttt cataaaaaaa cccctttcta taaatatata
    44701 ttgaattata ttcatactat ttatatatag aaataatatt gaagtggtga attgtgagtg
    44761 atatataata taaataaaaa ttcttataga taatatatat gcactgagct ttaaaaatgg
    44821 aacattaaaa tatgaaaaac atactttaat atagggcaat tatataatag aagggggaat
    44881 tgtcttgaat aacttactat ttttgattgg agtgattgca ttgagtaatg gtaatatctc
    44941 tatatttgat gataaaaata aatcaaaagg aaataataga gttagaaaaa acaaaaaaaa
    45001 tacaaatgat aaactttcac agtctacaca tggcaattta aggtttgatg caaatgacat
    45061 aaaaagaggt ttaaggctca tggatttaag tgaagaagat ttagaaatgg gaatggaaat
    45121 aataacaaga actaaaaaat acatgtcaag agatgaaaga aaaatactaa taaaaataga
    45181 aagtgtatta gatttagtta gaggaataaa aaaattaaat aatatagata tggtagatac
    45241 agaagatgaa acggattttt tcagaaaaat ggatagtgat gataaaaaga atatgatgat
    45301 aaaggaaatt atagatgtat ttccagaaaa aagaaaaaat tcagttgaaa aagctatagg
    45361 aatgaaaaag aagatagatt tatttgcaga attattttta ccagatgact ttggtgaagg
    45421 tggatttagt ttgagctctt tggcaaatat aaacaatctc ggtagtatga ataatctcaa
    45481 attgttagga agtcttttaa gaggtgatga tagtaataat gatgatgaag acaataatga
    45541 tgagttaaat tatgaagacg aagaattaga ttgtgaagac aaagaattgg atgatgatga
    45601 gttaacagat gaaggtgaaa tggaggataa tgaagatgaa ttagtagaag ataagaacac
    45661 aggctatgaa aatatagaaa atgatgaaga tatagtatac gatgaggaac tgtacaacat
    45721 taatgagcaa gaatccgaat acaattataa tgaaaaaaat actaaaacta gagctaagaa
    45781 aaaacgataa ttaactaagt acataaagaa aaaaggaaga aaaagtaatg atagaataag
    45841 attatctcaa ttactatata aaaccacttt aaaaaattca aaatttatta tataataata
    45901 atatgaaatc ctgaaacata cgataaggct tttttaaatt caacctacaa atgaaatacg
    45961 ggagaccgtg tctggtaaat tataacatgc ctagttagtt tggacgttaa aggttactgg
    46021 caagtcaccc acctgggagt gcctagggtg tgaatttact tagccaccgg tgtttcggga
    46081 caaaaaaagt gctactattt caaatagtag tacttttttt attaatatgc atttttctac
    46141 taaatacgcc taattattga taaattcaaa aagcaagtaa caattaagat tataaaagca
    46201 tagtattaat taggcttcaa aaagccaaag acttaataag aatcgcttac agggagggca
    46261 atgaaaaatg caagattata aaaaaaataa aagaagaatg atgaatcagc caatgtctac
    46321 aatgaatgaa gaagaagtgt atacagatga aataaattca gaagacatga gagggtttaa
    46381 aaaatcacac catcataatg gatgtaatac tgataataag tgtgagtgcc atgatgagtg
    46441 taatccatgt aaaccatgta aacctaaccc atgcaatcca tgcaaaccta atccatgtga
    46501 tgacaaatgt gaatgccatg acaagtgtaa atgtgattgt gaaccatgtg aaatggattc
    46561 agatgaatgt tttgaaaaca aatgtggacc agaatgttgt aatccgatat ctccaagaaa
    46621 cttctctgta tcaaatgcag tgccatttgc aatagaggct aatagaatat ttgatactat
    46681 gcaattccaa acatttacag atgcaacagg tccaaatgga gaaccattaa cttttgaaac
    46741 agaagtagta gaagtatttg gttcaattcc aagtgcaggt caagcaagtg taactataga
    46801 aaaaatatgc ttaagtaatg atggaatagt tatagacaca ggaatgacaa ctttagaaga
    46861 tttcgattta gacccattag gagatatagt aggaagaaac tgtgaaacaa cttttgaatt
    46921 tgcagtttgt ggagaaagaa acgctgagtg ctgtagacaa ggaaaaggca aatcagtagc
    46981 ttataaacaa agaggattaa ctgtagcagt tcgtaattta gtaatagagc taagaggtag
    47041 atgtggatgt acagagttcg ttgcattagc tttcccagca gtcagagcag gaggtggatg
    47101 taagagaaga gttgattatg tagaatttac ttttaacaca ctttcagcac caatatgctt
    47161 gccagctgac ggaagagctg ttactttaag acaagaatat caaactaacc taactgtaga
    47221 ttgtatagga aaatctatat taaaattaga atgcaacgaa tgttgtgaac ctttctatga
    47281 gttaatcata ccaaatgata tagatgtagt actttgctta caaaacacag ttagcacatt
    47341 aataagtgaa caaatagtag ttttagcatc accaaatcca atccaaccaa gacttgttga
    47401 tactttctct aaagtatgtg atttttcgca atgtgaacct aatcatggaa gtgggaagcc
    47461 aagttgccac agatagatag gtagatatat agacagttta aattataaat aaaaatcatc
    47521 taaggaaggc taccaaagtg tataatttac attggtagcc ttcacgtttt tataactagc
    47581 gtatagattt tagtgattta aaaagcacta tagtatgtaa tagacaagta aagattgata
    47641 ctatcgtcat tgtgtatata tatgcataaa tattaagttc tggaattgga agaaatacat
    47701 ataaagctat tagttgaatt aacatgccag taatagtatt tatacttgaa gctaattctt
    47761 ttcttattga atgtaaaatg ccagatagag tttgatttag ggacataaat agtggaacta
    47821 aaaacatagc ttttagatat tctcctgcaa gtgtattttt aaatactaat atacataaat
    47881 cttttccaaa gaaataaaaa aatattgatg atagtatgcc cacaaataaa gtaagaagta
    47941 tggagtattt gattttttta attacactct tacgctttct tagagccatt tcctgtgaaa
    48001 tagttggtat taaatttaca ataagcgctg aaccaacagt aaaaggtaaa aatataaagg
    48061 gcattaccat cccactgaca ataccataca tacttaaaga ttgttgataa gtcattcctg
    48121 ataatgctaa tcttgatggt atcatcatag aacttataga ttgcaaaagt atgtttgaca
    48181 ttctattaca agttatggga atagacattt ttaatgtttc catagaagaa ttgtaaaaat
    48241 cttttatgct tataatatac ctattgtcaa atgatgaatc tcgccataag caaataagca
    48301 taaatataat attgctcaac tcaccaatag atatacctaa tagagctata taacaattca
    48361 tagatttatt atttatgtac ataacaagta aaaaaacaaa taatatttta ccaatttgtt
    48421 caatgatttg tccaatagca gggattttta cattctttat gccatagtaa tatcctctta
    48481 gtacgtttga aagagttatt ataactatag caggacaaac agctagtata aatagattta
    48541 atttagcatc ttttaaaaat ttaagcgata aaaaagaact attgaaagat gcaactatag
    48601 atataattag tgctacgaaa aatgatatat ataaagttga tataaataaa gcattagtat
    48661 tgtgtctatc gtttaaagct tttctctttg caactagaca actaagtgca gtaggtatac
    48721 ctgttgttgt aacagctaag caaatcatca aaaagttaaa aatcatatga tagataccta
    48781 aacctgtttc acctagtgct cttgataaga atattttata taaaaaacca aatattctta
    48841 caataaaatt ggatataaat aaaataactg ttgatagtac taaataaggt actttcaaaa
    48901 aaatcacctc cttatctttt aaatatattc acaaggaggt gtaaaaattt ataattttat
    48961 aaattctggt ttcaatttat taaatttaga tacatattta aatcccatat tttttagtaa
    49021 tgaatatatg tagtcaaact cacatgcaac ttgacttata tgatgtgaat ctgaacctgt
    49081 ggttatgatt tcccctccca agtctttgta catttgaagt atatacttag atggggttag
    49141 gtctggaaga ttatatctat aacaagaggt atttatctcg atacctttgc catcataaat
    49201 agcttgttta agagtttctt caattatatc agaaaatagt ctatcatcta aaatagtgtc
    49261 ataaggtgca taccttttaa tcaaatctaa atgacctaag acagagtaat ctttataatt
    49321 cttaacaata ttatataaat aaagatagta attttcataa acttcatatt gagttttatc
    49381 tttaaaataa ttaccaaggt ataagtccat tgtatctata gcatggatag aacatattat
    49441 aaagtccaat ggatattgat gtgcttcctt tttgtatgta tccattaatt gagtttgaac
    49501 tccaaattca attccttttt ttattgatat tttatctttg tatttgcttt gaagagtctc
    49561 taaactctta aaataatctt cgtagacaat tgaaaaagaa tcatcagcat atacatcata
    49621 gtcaacatgg tctgtgaaac aaatttcctc caaaccgagt tcaatagatt tttttaccat
    49681 ttcttccatt gtagattttc cgtctgtaga gaaacttgag tgcatgtgat agtcgtaaaa
    49741 cataaatatt tccccttttt ataaaaattt tggtattata tatacatact aaataatatc
    49801 aaatatatat aaaagcatca ataaaatata aatacaatga gcggtgataa atttggaaaa
    49861 atacagaata gatttaaatg agaaaaaatc aactaaatat atacagatat ttaatcatat
    49921 aaaagaattg ataataaata aagagttagt agaacatgaa aaattgcctc caataagaaa
    49981 actatcaaat tttttacaag taaataacac tactatagtt aaggtatacg agcttttaga
    50041 aaatgaagga tatgtatata aaattatagg gagtggtact tttgtatcaa gtttaaattc
    50101 ttataaaagc ggtatagata acaggaaaaa taagattatt gtgcaaagag aagatttaat
    50161 tcattttgac aatgggaatc catctaatga tatgtttcct atcgattcat ttaaaaatgc
    50221 tgtaaatatg gcattatcta aagatggtag ttcaatattt gaatatgatg aaggtcttgg
    50281 ctctgaagaa ttaagagaaa aaatggtaga gtatctaagt gatggaaata taaaaactac
    50341 taaggaaaat attcaaataa tatcaggtgc tcaacaaggt atagatatag tttgtaaagg
    50401 acttataagt tattcagatg ttgtttttat ggaagaacct tcttacaatg gagcaattga
    50461 agtgtttaaa agtagaggtg caaaaataat atctatacct atgttagatg atggaattga
    50521 tataggtatc ttaaaattaa agttggaaaa aataaaacca agacttatat acattatgcc
    50581 taattttcaa aatccaactg gaatatctta ctcaacatat aaaaaaaaga aattgataga
    50641 attggcagaa gaacatgatt tttatataat agaagatgat tttataagtg attttgtttt
    50701 tgaatcaaag gacaatagaa caattagaag ttatgatgat aaaaatagag tagtatatat
    50761 aaaaagcttt tcaaaaatac ttatgccagg tcttaggata ggaattgtag aaatgccaaa
    50821 tgagttgtta aaaaaagttt tatgggctaa atattcatca gatatatcaa caccaggttt
    50881 aattcaaaaa tcaatgtatt actatatgaa taattttgat tggaagaatt atttgagtca
    50941 tatagagaag atatatactg ataagtataa attggcaaaa aacttgatta atgacaaatt
    51001 gagtggtaaa ttaaaagtta gaaaatcttg tggaggaata aacttttttt tagaattacc
    51061 aagaggatat acatctcaag catttacaaa ttttatgtta aataaaggag tgtcaatgct
    51121 tccaggaact tatttttttg acaatctagt ggatgataga ttctttagga taaatatagc
    51181 tcgcccaagc atggaagaac tagaaaaggg aatatctgta ataagtgata atatagatga
    51241 gtttttttgt gaatataaaa acaagttaga tataaaaagc aataaattat tttattaaat
    51301 aaatagaggt tttttaggag gaaaaaatgt ttgacaagaa gaaattagat aggattaatg
    51361 aattagcaaa gaaaaataaa gagggaatcc tttctgctga tgaaatcaaa gaaagagaaa
    51421 ttttaaggaa agaatattta gaaaacttta gagctcactt tagatcaaga ctagatagtg
    51481 tcaaagtagt ttcaccagaa gaatatgagc aatacatgaa aaacaataaa aattagaact
    51541 tagtaggagg aaaatatgaa cttaaagtac gaatttaaga atgcttggga ttttgaaaga
    51601 aaagaaaata ctattgaaca aattatgcaa tattctcgca attatatgga gtttttaagt
    51661 aagtcaaaga ctgaaagact ttcagtaaaa gaaattataa aattggctaa agaaaataac
    51721 tatatttcaa tagatgaagc tatggaaaaa ggaagcataa gttgtggtga taagatttat
    51781 gttataaata aagagaaggc agtagcactt tttgtaatag gtaaaaatta tatagaaaaa
    51841 ggtatgaaga ttataggaag ccatatagat tcaccaagat tagatttaaa accaaatcca
    51901 ctgtatcaag agagtaatct aggttttttt aagactcatt attatggtgg aataaaaaaa
    51961 taccagtgga cagctgttcc acttgcttta catggtatag ttatattaaa tgatggaaca
    52021 aaagtggaca tatctattgg ggaagaagat agtgacccag tattttgtgt aactgattta
    52081 ttgattcatt tggctggaga ccaaatgcaa aagaaactat cagaaggaat tagtggagaa
    52141 gctttaaata tattaattgg gaatattcct ttagaagatg aagaaaaaga acctataaca
    52201 gcaaatatat taaagatttt aaatgagaaa tacaatatag ttgaagaaga cttattaagt
    52261 gctgaaattg aagtagttcc agctggtaag gctagagatt tagggcttga taggtctatg
    52321 gtgttgggat atgggcatga tgatagggta tgttcatatg ctgctgtaaa agctatacta
    52381 gaaactgaac aaccagaatt tacttcagtt gcattatgtg tagataaaga agaaattggt
    52441 tctaaaggga atacaggtat gcactcaaag ttttttgaaa atactgtggc tgaactgatt
    52501 gctttagaag gagattattg tgatattaaa gtaagaagag ctttagcaaa tagtaaggta
    52561 ttatcagctg atgtttctgc tggatatgac ccaaattttg gagaagcata tgaaaagaga
    52621 aattcagcat atatgggaaa tggagtagtt ttaactaagt atacaggttc aagaggaaag
    52681 agtggatgta atgatgctaa tgctgaattt atgtcagaag taaagagaat ttttaataaa
    52741 ggaaatgtag tatggcaaac tgctgaactt ggaaaagtag accaaggagg aggcggaact
    52801 atagcccata tattggcaaa tcaaggtgca gaggttatag actgtggtgt tggagtttta
    52861 aatatgcatg caccacatga gattgtctct aaagtagaca tatatgaaat gtataaggga
    52921 tataaggcat tttttaatat aaatttataa gtaaaaatat aaatgtaata agtgaataaa
    52981 ggctgttgta taaacaattt aatctgttgt acaacagtct tatttttatg taaaaatagc
    53041 aatttgtcac actagagaaa ataaaagaaa atactgtcaa attaaaaatt atttaaaaaa
    53101 aattgacaac gatttcatct tgttataata tgtaataaag aacttgttat ataatgttat
    53161 aaaaatgtta catagggagg tgagcaaaat ggatgaaaag agacaaaaaa aagaaatgga
    53221 tttagaagta aattcctttg ttcctttata tcaacaacta tatgacaaca taaaaaaaca
    53281 aatagcatct ggcatatata aaccaggaga taaacttcca tctgaaggag acttatgtaa
    53341 agaatttaat ataagtcgta taactgtgag aaatgcactt aatgaacttg taaaagaaga
    53401 tatattatgt aaaaaacgtg gtaaagggac ttatgtaaca ataccagaga gaatagaagc
    53461 aacatgtgca ggaaatagtt ttactaattc ttgtcatcgt attaatgcaa aaccaagtac
    53521 caaaataatc tctgttttaa taaaaaaagc agataagcaa gtagctgaag ctttaagtat
    53581 tgaactagaa gagaaggtaa tatgtattaa aagacttaga ttaatagatg aagtacctgt
    53641 tatttttgaa gttgactatt ttagaataga ttacatgttt ttattaaaag aagaattaga
    53701 agataaatct ttaatggagg ttatatctaa taatataagc acattaccta aacgagtaga
    53761 aaatatattt gaagtaaaac attcaaacaa agaatattct gactatctta aatgtgcaag
    53821 taatatgcca ctattgaaag taagacaatc ggtgtataca gaaaataatg atgtcttata
    53881 ttacaatgag caatttataa gaagtgataa gtacaaatat gcagtatcag cagaaatata
    53941 atctatattt agtaggagga tgagtatgaa aaagataata ttagcatctc atggagattt
    54001 ttcaaaaggg cttttaaatg cagtaaaaat gatagtagga gatttagcag attgtgttag
    54061 ttcgtatggt ttgtaccctg gacaaagtgc ttcagatttt gctttagaat tagaaaaaac
    54121 aatatcagaa gatatagaat gtgaatatat aattttatct gacttatatg gagcaagtgt
    54181 atgtacagca atgttaagat taactaattt acataatgtt aagttatttt ctggaatgaa
    54241 tttgaatatg gtattagaac ttcttacaag gttttctgat gaattaacag ttgaagatat
    54301 agaacaatta gtggaagaat ctagaagagg aatacaaagc gtgacattac aaattaaaga
    54361 agaagaagag gtattttagt ttatgaaaaa aaagggaata ttatcagtat ttaaaagtaa
    54421 aaaaccaatt atagcaatga tacacttaaa aggagatact ccagaagata tctttgaaag
    54481 agctaaaaaa gagattacaa tctttgaaga aaatggtgta gatggaataa tgttagaaaa
    54541 ttactatggt aattattatg atttagaaag aatacttgaa tatgtatcaa aagctaattt
    54601 gtcaatacca tatggagtaa actgtttaaa tgttgatact atgggatttg aactggcaac
    54661 aaaatataat gctagttata tacaggttga ttctgtagta ggtcatgtta aacctagaga
    54721 tgaagctact ttagaagagt tttttaaatt acaacgttca aaatgcccag cgtatttaat
    54781 tggaggcgta cgttttaaat atcagccagt attatcagaa aatgatgttg aagaagattt
    54841 aaaaatagga atgacaagat gtgatgctat agcagttaca gaaaatgcta caggtcaaga
    54901 aacatcaatg gaaaaaatag aactgtttcg taaaaattta ggagacttcc cattggttat
    54961 agctgctgga gttacattag aaaatgcaaa aaaacagctt gaattaggag atatggcaat
    55021 aataggaagt tactttaaag ataattacaa agattttggg aatgttagtg tagaacacgt
    55081 aaaaacattc atggatgaaa tcaaaaaaat tagggaggaa ttataatgat taaattagta
    55141 agagtagacc acagacttat acatggacaa gtagcattta catggacaaa gtttttaagc
    55201 acagactgta tattgatagc aagtgatgaa ttattaaaag atgaattaag aatggcaggg
    55261 cttaaaatgg ctaaaccatc taatgttaag ttagtaatga aaagcatagc agattctata
    55321 aaagcactta actcaggtgt tactgataaa tataacttat tgatactttg tgaatctgta
    55381 gaagatgttt atagacttgc taaagaggta aaagctatta aatctataaa ccttggtgga
    55441 acaaaatcag atgataatcg tgaaaatata tctaaagcag tgcatgtatc aaaagatgat
    55501 ataaagatga ttaaagagtt agattcagaa ggcgtaaatg tatttgtaca attagttcct
    55561 gatgatgatg ctacaaatgt aatgaaatta atataatttt agggggatga aaatggaatt
    55621 tacacaagtt attttgataa ctctaattgc attctttgca tatatgcata gttttgtagg
    55681 ttctacaatg cataatagac ctatagttgt tgcaccactt gttggtttag cactaggtaa
    55741 tcttcataca ggtatagtaa taggttcaac attagaatta gtatttatgg gtgcatttcc
    55801 tgttggggca agtaatcctc ctgattttgt gtctggttct attattgcca cagcgtttgt
    55861 aatattaacg ggtcaagatg tatcagcagc agttgtactt gcagttccta tagcaactct
    55921 agtattgctt atagataact tcttaatgac agtagtactt acatggggag ctcatattgc
    55981 tgaccgttat gcagaagagg ggaatattga aggcgtagaa cgtgtgcaat tattatttgg
    56041 tataggaaat aaattaatat tagcaataat agtaggtata ggattttcat taggtgttcc
    56101 agtaatagaa aaaatacttt catttatacc atcatatgta actcatggaa tggatgttgc
    56161 agcaggcgtg attccagcaa taggttttgc catgttagct aggatgatgc ttaataagaa
    56221 aacagtagca tttttattat taggatttat attggttgct tacctaaaca taacagtaac
    56281 aggagttgca ttgtttggat tagcaatagc tttaatatat gttaactttg taggagagaa
    56341 ggaggtaata gtagatgaca acgagttcta agaagttaga tacaatttca cccgatagta
    56401 aaataacgag gaaagacttt tggaaatgct ttagaaggtc attgacatta gattcatctt
    56461 ggaactacga acgtatgcaa aatatagcat atgcatacat gatggcacca ataatccgta
    56521 gattgtataa agatgataag gaaaagaaat ctaaggcttt aaaaagacat ttagaattta
    56581 tgtcagttac tcctcatata agtactcttt tggtaggtat atctggagct atggaagaag
    56641 aaaatgcaaa gaataaagaa tttgatgcta atagtataaa tgctgttaaa tcaagtttaa
    56701 tgggtccagt ttctgggata ggagattcat ttttctgggg aacattaaag cttatagcag
    56761 ctggagttgg tatagcttta gcttctcagg gtaacataat gggaccgatt ttattccttt
    56821 taataataaa tgttcctcat tttattatac gctatatatg tctagataaa ggatttaagt
    56881 atggaactca attctttaaa gatgtgagta gttcaagtat agtttcaaaa gttatggaag
    56941 cagcttcaat gttagggctt atggtaattg gaggtatgac tgcatctaat gtaatgttaa
    57001 aacttagtgt taatgtaggt agtggagaat gggcagagcc tattcaaact tacttagacc
    57061 aaataatgcc atgtatgctt ccagctatga tattcggtat tatgtattgg ttattaggaa
    57121 aaaaggtaaa gacaactacg atattaattt cagttatgat tatttgtata gtattagctg
    57181 ctattggaat agtataaata aaaaaatccc aagttcattt gaacgaggga ttttttgact
    57241 aaattaaata aaaaagaaag atggttcata ataatttata agcatttatg tgatagttat
    57301 aattagctta ttaattagtt ataaacccaa aattaagcac tactttatta aagttattat
    57361 attataattt cgaaatactc acataatctg tttagaaatt tatcttctaa tggggaaaaa
    57421 gttttctttt tagagtaaat aaagaaaaat tttctagtaa aatcaacacc ctttatttta
    57481 taacatttta ttttacctgc attgagataa tcaatagctg aaatgtacga tataaaggag
    57541 actccaagac ctaatctaac catttcctta atagcctcat ttgattctac atgagctatt
    57601 acatttaatt tacttactgg aaagttattt ttactaagtg tgtttagtat taagtttctt
    57661 gtacctgacc cttcttttct cataataaaa tttagataag ccaattctcc tatatcgata
    57721 caattatttt tattatcaat tttaaaatct gaaggagtga taagaacaag ttcatcatct
    57781 aataagtcta ggtactctat ttgaggatta ttgattttag aaccaactaa tccaaagctt
    57841 attcgttcat ttaaaatttc tgatatagca tattgagaat cataatggct tatggaaaat
    57901 tttacatctg gataactcat agaaaaactc ttcataaaat caggtaaaat ataagtttca
    57961 ggtatggaac tacatgctat atctataata ccttctattt ttcctgaata ttcttttata
    58021 tcataaattg cacgtttgca attattcaat atatatatag catgttcata aagaatttca
    58081 ccagattttg tgagtgtaat aactttgttg cttctattta taagaacagt ttccaactct
    58141 ctctctaaat tctgtatgtg tgcacttaca gtaggttgag ttaaaaaaag ttctcttgcg
    58201 gcctttgaaa aactctgatg ttttgcaaca gcaacaaata cttcaagttg tttaaaatcc
    58261 attatttaat cctccttaaa ttatctaaaa ctattataac atatttgata aattaatagt
    58321 caaaggtgat ttttaaaata gaaaaccttt aaatattcat ggagtttttg attgtttagg
    58381 aataatttgg tataatattg taaggtactt acaataaaaa tatcgtaaat tgaattttca
    58441 aaattcaact ttaaagtgtt ttttattaca gaaaaattac aattagcttc t
//
LOCUS       DACTZW010000014        57475 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.014, whole genome shotgun sequence.
ACCESSION   DACTZW010000014 DACTZW010000000
VERSION     DACTZW010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 57475)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57475)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57475
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.014"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            362..1897
                     /locus_tag="JAM15_04725"
     CDS             362..1897
                     /locus_tag="JAM15_04725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005540409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAT6797565.1"
                     /translation="MINDILTLLSERSDFFIKLSIEHLMISIISIIIAIVLGGIIGII
                     VSEFHNSSKPILGTINFLYTIPSISMLGFLIPFSGIGNTTAVIALTIYALLPMVRNTY
                     TGITNVDKNILEAARGMGSTDFQILYKIKLPLALPVIMSGIRNMVIMTIALAGIASFI
                     GAGGLGVAIYRGITTNNTAMTISGSILIALLALIFDFILGLVEKFFQRKRKKKNRKKV
                     FAILGSLILIATIFTSYLFNPSKTQTIHIATKPMTEQYILGEMLDILIEKNTGLNVEI
                     TQGVGGGTSNIQPAMKNGEFDIYPEYTGTGWNMVLKKNELYTESMFSKLQSEYKTKLK
                     MQWTGMYGFSNSYALAVRKEVADKYNLKNISDLKNVSSKLTFGAEYDFYEREDGYTPL
                     CNTYGLNFKDTVDLDIGLKYQAINEGKIDVMPIFTTDGQYSVSDVIVLKDDKNFYPSY
                     QCGNVVRLEVLEENPELSEVFKMVGDILTDKEMAKMNYDVENNNLEPREVACEFLNKK
                     GLL"
     gene            1913..2674
                     /locus_tag="JAM15_04730"
     CDS             1913..2674
                     /locus_tag="JAM15_04730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008751341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6797566.1"
                     /translation="MTPIIQFKNIKKQYNDKTIIDNLNLDIEKGEFLTVIGSSGSGKT
                     TLLKMINGLILPDGGNILINQTDIKNEDLIKLRRRIGYCVQGSVLFPHMTVEENISYV
                     PNLLSKKNKLEVKSAVNKWMEIVGLPNDMKVRYPSELSGGQQQRVGIARALASSPEIL
                     LMDEPFGAVDEITRKQLQKEIKEIHKKTGVTIIFITHDIYEALILGTKTLVLNHGVVQ
                     QYDTPENILNTPANQFVDQLLNIRKSIIDDDNLKE"
     gene            3012..3881
                     /locus_tag="JAM15_04735"
     CDS             3012..3881
                     /locus_tag="JAM15_04735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAT6797567.1"
                     /translation="MDNNLITIEKTLDYIEKHLLDEMLDLNVISKEIGYSKYHLHRMF
                     TSVVGFSIHNYIQRRRLTEAARMLIFTEKPIIEIALISGYDTQRSFSTGFKKMFKHSP
                     KFFRKHQDFLPLQLKFDINNRKRLHGGMVLDVKKVNCTDINIVGYSGKVKKGFHVIGK
                     CWRDLHKNKELIENKVDLDFLIGVNDYSNFKEIENNPTFTYIAGVQVATFGKLPNGME
                     KFVLPKSNYIVFTFIGKNEDSMQNVVEYIYQEWFLNSSCQFNENNLYDFVKYGEKTDK
                     NGLSEIQFWVPII"
     gene            4075..4326
                     /locus_tag="JAM15_04740"
     CDS             4075..4326
                     /locus_tag="JAM15_04740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HAT6797568.1"
                     /translation="MNVENELLKNLDRLHTTELGVVRIKKNLSLETNDVVNWCKTKIE
                     SPNAIINRKGKNWYISVYDCIITVNAHSYTIITAHKEKK"
     gene            4438..5217
                     /locus_tag="JAM15_04745"
     CDS             4438..5217
                     /locus_tag="JAM15_04745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAT6797569.1"
                     /translation="MNNTVKEKLAESLTSDTTDILPYLPYLLQDFWELGSSPEQMLQL
                     FRKHIPFNEDTKVLDLACGKGAVSVKLAKELNIHIKGIDLIPEFIDYARRKAIEYKVD
                     ALCDFEMNDANSSVKIEHDYDCVIFGAVGDILGNYKETISKLLPTIKSKGFILIDDAY
                     VVDKSTNEQLNFERVYPTYNEWCILFKELGLKLIECIPCLELENDVEEEMNWIITRAN
                     ELIKKYPSQKDMFEQYVISQKNEYTDLQQDLVGATWILQKE"
     gene            complement(5352..6002)
                     /locus_tag="JAM15_04750"
     CDS             complement(5352..6002)
                     /locus_tag="JAM15_04750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAT6797570.1"
                     /translation="MNIVMINGSPKVNKNNSQYFLSELKQLIQNDNKVFTFKVDSTSK
                     YPDALNAILNCDRLIIAFPLYVDGIPSHLLHFLEKCEKFLKTQNKKPIPVYAIVNCGF
                     NEGEHNHLAIQMIEHWCKKINFTWVQGIGIGAGEMFGSLESVPLGKGPKKDLGIALKE
                     LSKNILSDNIHIDDSNKSTIFISPNFPRFLYKLMGNHQWNTQAKSNGLTKSDILKK"
     gene            complement(5999..6502)
                     /locus_tag="JAM15_04755"
     CDS             complement(5999..6502)
                     /locus_tag="JAM15_04755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HAT6797571.1"
                     /translation="MRLLIHDLTDKELEKLLPKLDDNIKILPNTKEIHKCIGCFGCWI
                     KTPSECVVKDYYSNMGKLINDSDGIIIISRCCYGGFSPFVKNVLDKSINYILPYFVIK
                     DNMMRHKSRYDKQINLKAIFYGDCITEAEKETATKLVNGNAINFNIKEHSVCFYENIQ
                     DIRGESI"
     gene            complement(6551..7066)
                     /locus_tag="JAM15_04760"
     CDS             complement(6551..7066)
                     /locus_tag="JAM15_04760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAT6797572.1"
                     /translation="MLEYIILGFLMEKELSGYDLKQIMSESTSYFFDASFGSIYPALK
                     RLETKGYIHYHEVIDGNKLKKLYSITNTGKEVFLEWLKKPINFSKTKQDHLVNIFFYK
                     YLPKEIIETNLKMLITEVELLLNKLSKQKNDAEENHCVDQYTYMYATMIYGVDYYNFV
                     INWCKDLLKNL"
     gene            7382..7873
                     /locus_tag="JAM15_04765"
     CDS             7382..7873
                     /locus_tag="JAM15_04765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAT6797573.1"
                     /translation="MRTIDIKGENMRELLKWVSIINRYNTNYIDRKLADIGINNSQYF
                     YVLHICNNPGITQDTIFEKILVNPSNITRALANLEKEGFITREPGVKDKRTWHLYPTE
                     KSLECYDEILKITNGYVEELLSSFEKEEQELFMSMLKKVAFLAIDMNEEAKLEAKENG
                     RKI"
     gene            7857..9260
                     /locus_tag="JAM15_04770"
     CDS             7857..9260
                     /locus_tag="JAM15_04770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HAT6797574.1"
                     /translation="MEEKYKEPLEYEKVSKLLTKYAIPSIIAMLVSALYNIVDQIFIG
                     QGVGVLGNAATNVTFPLTTICTAIALLLGIGGASKCSLELGAKNSEKATKAAGNSICL
                     MAVFGISLFIVVSIFLTPLLKFFGSTSEILPYAHTYTKITSIGLPFLIMSTGMSKLIL
                     ADGRPKASMFCMLIGAVINTILNPLFIFVFNMGIAGSALATVIGQLISFGISVHYIKN
                     FQHIKLHKKSFKLDSIIYKHIFALGSSSCFNQLAMTVTQIVMNNTLAYYGARSVYGSE
                     IPLACVGIIIKVNMIFISIIIGISQGMQPIIGYNYGAEKYNRVKEAYKFAVGSATIIS
                     VIAFLCFQFFPRQITSIFGNGNETYFIFAEHYFRTFLFLTFINGVQIVSSTFFTSIGK
                     SVLGLFTSLTRQILFLIPLIVILPMFMGIDGVMFAGPIADAAAAMVCIYFAVHEMKSL
                     TIKQNNLMSNHNKIAEV"
     gene            complement(10157..10750)
                     /locus_tag="JAM15_04775"
     CDS             complement(10157..10750)
                     /locus_tag="JAM15_04775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAT6797575.1"
                     /translation="MISDSISKRRSIRKYKNQSISHETIEKIIEAGINAPSSKNRQPW
                     RFVVITEKEKESMLKAMSKGIQNEINDNGLLPGSRQHIAGANYTVEIMKQAPVTIFIL
                     NILGKSPLEKLSPEERFYEMANMQSIGAAIQNMSLTAVELGLGSLWICDVYFAYRELC
                     EWLNTDSQLVAAISLGYPDEEPSRRPRLQLSDVTEWR"
     gene            11598..12248
                     /locus_tag="JAM15_04780"
     CDS             11598..12248
                     /locus_tag="JAM15_04780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HAT6797576.1"
                     /translation="MDFISSILQGLLSILFNFTGDFGISIVLITLIVKLVLMPLSLKQ
                     RFSVKKQQELAEKMEHIKEKYKNDTKELEKQIQVSSVESMKSMLGCLIVLVQMPVVYA
                     LYHVCLDMTKEFTTIIIPWIANLGTFDNLFILPCIYTLIMLASNLVNYIPYLKINSQV
                     KFNKQMAVVTIITSLILTVRTPVAIGLYFITSAIYSLIEDICFRMYFNRKNRIVTK"
     gene            12462..13133
                     /locus_tag="JAM15_04785"
     CDS             12462..13133
                     /locus_tag="JAM15_04785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6797577.1"
                     /translation="MAKILVVEDEKRMQSIIVEYMQKGGYTCITANDGVEALTILKSN
                     NIDLMILDIMMPYLDGFSVCRVSREMTNIPIIILTAKGEEEDKLKGYEYGADDYITKP
                     FSPKVLLAKVNALLRRYTTDIPKNSLSLGKIFIMVASRQVYVEDKLIDLTYKEFELLR
                     LFMENPNQVFSREKLLNCIWGYDFEGNTRTVDTHIKTLRKKLGSEGHHIVTLIRSGYK
                     FEVKE"
     gene            13130..14260
                     /locus_tag="JAM15_04790"
     CDS             13130..14260
                     /locus_tag="JAM15_04790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAT6797578.1"
                     /translation="MNSLRKIIEKLKNVDISNWIKQNFGLYSVRKKVFLLSKLSGALI
                     ILFYLVVEEFSINSKFEFWIWFIILVIFIMSIDFLLGKFISEPITSINKSAKSMSQLD
                     FSNPCTVNTNDEFGELSRSLNTMSTNLQQALSDLESANIQLEKDVNKERMLLEQRKEL
                     VDAISHEMKTPLGIIRAYTEGLMDEVDEEKKKNYMNVIIEETDRMNNMIVSLLDLSAL
                     EAGVSKLNPERFDFIEFVETVAGRLLIDIPDANFYFTYDLPEYEVFVVADKMRMEQVV
                     ENLIINAKKHVVYNGNLDLSITCENGLLLFEIYNDGRIIEQDEISKIWSKFYRSVQSQ
                     RKGGSGLGLAIVSQILTMQGLEYGVNNRDRGVEFYFMIPIDE"
     gene            14690..15535
                     /locus_tag="JAM15_04795"
     CDS             14690..15535
                     /locus_tag="JAM15_04795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6797579.1"
                     /translation="MIKVGELKFSYGKDKQILHGLKFEVKEGEIFGFLGPNGSGKSTT
                     QKILNGVLKGYNGHVSLFGKEVKAYTESLYQKIGVLFEFPYLYTNLSAIDNLEYFSSF
                     YPKNQRRDIYELLDLLEFKKEFINKPVSSYSKGMKQRISMARALVSNPKLLFLDEPTS
                     GLDPSGAVLFRKIIEEERKKGTTIFLTTHNMLDADLMCNNVAFIADGKIMVIDKPKNL
                     KMKNSNNKVEVEFVYNGNRDIEIVDIQELESGITFKYDEILSVHSKEPTLEEVFIKYT
                     GRMLV"
     gene            15535..16563
                     /locus_tag="JAM15_04800"
     CDS             15535..16563
                     /locus_tag="JAM15_04800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6797580.1"
                     /translation="MYSKFFTLVKKDFWMMIYGKFFVLTLGSLILYSCYINFGYVKFM
                     DEDSYHNNVYLYNPENISMSASPLINQVSSIGELKAKLDEDTSAVCIDMSSSKPKVIL
                     HESIKGVDNYRADYALSLLSSEKDHNSKISDNNAIIQINDKDTSEIKQRKDMTCEILF
                     FEIVAIGFLGIASLLFKEKQMGVMRITGILPVKRSLFILSKIFAFLICDLCFTVLLVV
                     FNIGFFEGVKILPQVLVQASILSIIMSLIGIGCSMLLRDFKQFSLIYLVVAVFITTPI
                     FLSANTSFEIDWIKYHPFYHVYSQLKNAFFMNFSKELVYFVVCSLTIIVLFLLVKYIF
                     NKELVREG"
     gene            16566..17579
                     /locus_tag="JAM15_04805"
     CDS             16566..17579
                     /locus_tag="JAM15_04805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6797581.1"
                     /translation="MIGLHYQLKSIKKDKMCIISFFLPVVMAILINFMGTIDISSLGE
                     IRFGIVKDTLPVQTEQWLKKYGMVSVYDTKMHLIREIKDIKTDTIGVVRDGKGIKTVL
                     YGNEINAIKNVGKTLPEMFRLKGDLKDVEVTILPKDSILKEFQNVFIAMILITAMFMG
                     CTFNAMNIISEKEDGISFINEVLPQSRSQYIIQKVFLGLLCGCLSSMITVFICLDISI
                     LDMIMMLLLVVFSAFISSLIGLFIGKLSEGLMVGIVYIKIVMILFIGTPLLIYLLGVN
                     TRGIGNLCYIMPSVATFNGIMEIINGNVIIIKDIVILVVHCVVWFMIYIILDKKRKLS
                     FSR"
     gene            complement(18096..19346)
                     /gene="cme"
                     /locus_tag="JAM15_04810"
     CDS             complement(18096..19346)
                     /gene="cme"
                     /locus_tag="JAM15_04810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter Cme"
                     /protein_id="HAT6797582.1"
                     /translation="MENKNTNSTWKKKVILFLASQYISLFGSSLVQMAMIWYVTLQTS
                     SGVWVTVLTVCSFIPQMIISFFAGVWADYYNRKVLIIVSDSTIAISTLVLILFMMSSN
                     GTTSELIAISVISVIRSLGGGVQTPAVNAMIPQLVPEEHLMRFNGINSSLQSIVQFIV
                     PIVAAAILGFGNKINQVLLIDVFTAIIAIVLLIFIKIPKHNIPKQTEKVSFFADMVSG
                     IKYCFSDKFIRKVLFTYGAFMLLCVPSGFLIGLLIERTFGKGYIYLSIIEMIGFLGMV
                     LGGLIIGVFGGFKNRNKTFFLAILSYTIFSIILGLVTQAWQFFIFMFFTNFSIPIIQA
                     SAMTMLQEHVAPQMLGRVLSLPIIIYTGFIPLGMMIFGPMADVISINNLIIIAGIILL
                     FFALAIPYSKQFYKQGISKSNESE"
     gene            complement(19432..20178)
                     /locus_tag="JAM15_04815"
     CDS             complement(19432..20178)
                     /locus_tag="JAM15_04815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAT6797583.1"
                     /translation="MDTYTTSKVADLIGVHPNTVRLYEELNLIPKPKRNTNGYRIFND
                     FHIEQFRFARTALKIEVVQRGLRKDALEIVRTSANRDFDKAISLVNQYLQQLEIEKSN
                     AEEALTIVTQILNGNTPETNKLFLTRKETAEHLNVTIDTLRNWEMNGLLKVKRKQNGY
                     RVYTDEDIKRLKIISALRCANYSLSAILRMLNALSSNPNTNIKTVLDTPKDDDEIISV
                     CDKLITSLKEAEHNAKTMKSHLQIMKKQFS"
     gene            complement(20303..21325)
                     /locus_tag="JAM15_04820"
     CDS             complement(20303..21325)
                     /locus_tag="JAM15_04820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HAT6797584.1"
                     /translation="MNKNNCLDLIFEKVDPSSVGMSSEKLSQLEPLIISQYSNINGII
                     IARKGKVVFEKYYNGYNADDTFHVASVTKSIISALIGIAIDKGYIKDVDQKVVDFFPE
                     YTCSPSEICKKAVTIRHLLTMTAPYPFKNMTESLERLCKQKDWIKYTLNQLGQKGEIG
                     TFKYSSAGTHLLSAIITKTTGKSAREFANEYLFKPIGMKVIPDYDMKDFSFEDFFGKN
                     LKGWAKDRQGYSIGGWGLTLSARDMLRFGFLYLNDGIWNNKRIISKSWIEESVKMNSN
                     EYGYLWWICKKDGVLWYSAMGTGGNAICCIPQYDLVIAIPSKIVFKPRDRWEFIEKYI
                     LTSIID"
     gene            complement(21325..23745)
                     /locus_tag="JAM15_04825"
     CDS             complement(21325..23745)
                     /locus_tag="JAM15_04825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HAT6797585.1"
                     /translation="MKEIKINGAKIHNLKNIDVSIPKDKLVVATGVSGSGKSSLMFDI
                     VFEEGRKQYLQSLGILAGIDSEDKFDNIQGLAPTIAVQQNIIRQSNPRSTVGTRTNIL
                     NMLTLLYSVEGQIMCTMCDTPVSDNLICNNCGYEEERLRPSYFSYNSSDGMCMKCSGH
                     GAYFEITIEKLVLDKHDTLKQVLDRAKITPGYLRVFSKKFNDYLDIQFLQLPEEIRNE
                     VLYGHYENGKKSSSLSKVFHNRYKRGEDLNGVYTMTACSDCNGFKIGEEARRVLLNGK
                     HIGELGKMTILEIDDFLKILINQGNLNTFGTNLVNDILSKTRHLIESRLGHLSLYREM
                     STLSGGEMQRLFLNSHLDSEMDSLIYVLDEPTAGLHESEKIDILKSIKKLKDLGNTVI
                     VVEHDKNTIEMAEHIIDIGPKAGVEGGQLVYQGDLEGLLQSDKSLTGQYLSGKYPMPN
                     RTSNKNITHTDKIPCITIQNANTNNLKNVTVSLPLGAMVGISGKSGSGKSSLISDTLL
                     PLLRSQFNNHTINNQTNSSESEIGEEDDYAVVETIADRLIGTKHISGYSEISQSPIGK
                     NMNSTPASYIGIWDKIRTLFAGQPESLERGFTAGHFSFNSKGACPKCSGSGYEKVWLG
                     NNLSIDHICSECQGKRFNDESLSIKYKNKNIHDILNMSVSESVHFFKDIPNIVSHLNV
                     LEQIGMGYIKLGQPTPTLSGGESQRIKLAKEIGKKRNGNILYVLDEPTTGLSLYDTSK
                     LIQLLDELVENGNSVIVVEHDIDVLNVCDWIVELGPEGGDKGGYIIAEGSPKTLKENP
                     KSITGRYL"
     gene            complement(23831..24751)
                     /locus_tag="JAM15_04830"
     CDS             complement(23831..24751)
                     /locus_tag="JAM15_04830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAT6797586.1"
                     /translation="MTNAKSKKEYLNRICKVQDYIEEHLHEPLSLDELSNIAGFSKFH
                     FHRIFKAIEKETLAQYVNRLKLENATAFLIHRTDMTVTDIAHYFGFTDSAVFSRAFKN
                     YYKISPIKYRNNYSKNCKEPYKISQYNRSISKPKCKNTREVKGEIKILELDNMNTIYT
                     RYTGSYGNLTSTFPKLLERLFTYASEQNLLGLENTQILAIYHDNPQFTQEHQLRTSIC
                     MTIPDNIVVKENDNLGNMIIPSGKYLVGHFDISKSEYSDAWDFMYNEWLSNGNYKLRA
                     SFPFEVYLNNPHNHPQNRHLVDIYLPIEPF"
     gene            25360..26286
                     /locus_tag="JAM15_04835"
     CDS             25360..26286
                     /locus_tag="JAM15_04835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797587.1"
                     /translation="MSNSFYQLNSAVLYFNEKRDVTRIRFNHYVMRKENIQRLKGTLP
                     RGQFMMTVRKAASDLDVSISTISRLVNEFIDLGILRLISRGVKGNCCSVYSYVCSESS
                     NAEIVTKNGDIFKNIEKYIDATINNNQKTMKYKHRNELFKNSNTNTYSRINQESIDKD
                     YDLIIHTGYETENETKKKELLKNNLNKKNLNKNTFENLDEDLTEDSTYKNPESIHEII
                     IRKLNSESGKNFKADLSITKALIDKRLKEGYSLEDFYKVIEAKVRRWRYTDMEIYIEP
                     TILFGYEFESYLNEESSLSACNYGDMCYEDMY"
     gene            complement(26645..28297)
                     /locus_tag="JAM15_04840"
     CDS             complement(26645..28297)
                     /locus_tag="JAM15_04840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp21"
                     /protein_id="HAT6797588.1"
                     /translation="MNKKNLAILISGMMFFSSSSAIFADNTTKQERLIGKTRYETAVE
                     VSKLGWVQSKTAIIVNGNSIQSALCANPFAKLKNAPILLVNNNSIENSTKAELKRLGV
                     DNVYIVDSGNSISSKVENEIKSLNIKINKIVGNNIYEMSTNVLKEIDKIKKVENVAVV
                     NGLKGLSDAVSIASPAAIHNMPIILVSDENSNDSSINFLNNRSIKKSYIVGGNKILSD
                     NTVKKYPNRERISGSDRNNTNAKIIDKFYKDKKINNVFVAKDGINQENALVDSLSIGV
                     LAAKENSPIMISNGSLVNSQKEFIKNKDIDEITQVGGGYNQKAFEDILKLKNVNIRNK
                     TKKISLIQAKEILKQALPGSNILVCYYDEDDNEYDCKVIKDNILYEIEIDAYSGKIIE
                     IEKDDDLNDNNLGTQNISLDKAKSIALDAVPNGNLIYCKYDAEDNEYEAKVIKNKKTY
                     ELEISAFDGRIVDIDMDNDSDDDFDDNDKNNSNTNDNSSIISAEKAKSIMLDKVPGGK
                     IVKFKYDEDDKEYEGEIIKGKTEYEITINAITGKILEFEIDD"
     gene            28896..30017
                     /locus_tag="JAM15_04845"
     CDS             28896..30017
                     /locus_tag="JAM15_04845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HAT6797589.1"
                     /translation="MEAKKLGFGLMRLPIKDENDVTTIDMEHLNKMVDTFLERGFTYF
                     DTAYVYHMGKSEIALRESLVKRHKRESFTIATKLPLMALKKKEEQETIFNEQLEKCGV
                     DYFDYYLLHNIGVSHYEVAKKFDSFKFIEEKKKEGKIKNIGFSFHDSAELLDKVLSEH
                     PEVDFVQLQINYLDWDNESIQSRKCYEVAEKHNKPVIVMEPVKGGTLAKIPEKAEKLL
                     NDYNPDMSISSWAIRFAASKDNVMMVLSGMSNMEQLLDNTGYMQNFKPFVQEEYNIID
                     EAVEIINESILVPCTACQYCVEGCPKNIAIPNYFALYNAEKQALNTGFSTQMVYYNNY
                     TKTYGKASDCIECKQCEESCPQHIKIIDALKNVAETFEK"
     gene            30053..30466
                     /locus_tag="JAM15_04850"
     CDS             30053..30466
                     /locus_tag="JAM15_04850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAT6797590.1"
                     /translation="MTISEVSKKYELSADTLRYYERIGLIPPVNRNKSGIRSFTEEDC
                     DWVNFIKCMRGAGLSIETLIEYVAMFQQGSSTIKARKELLIEQRNQLAKRIEEMQKTL
                     ERLNFKIDRYEEGIVEKEKVLKSSRNKKMEAVSYE"
     gene            30459..30998
                     /locus_tag="JAM15_04855"
     CDS             30459..30998
                     /locus_tag="JAM15_04855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HAT6797591.1"
                     /translation="MSKNVLIVSASPRKGGNSDLLCEQFIQGALESKNQVEKVFLKDK
                     DINYCTGCGACYEKEASCSQTDDMGEILEKMIEADVIVLATPVYFYTMNAQMKTMIDR
                     TCSRYTEICDKDFYFIVAAADENVADMERTIEGFRGFTSCLNGSKEKGIVYGVGAWNV
                     GDIKGSKAMKQAYEMGKLA"
     gene            complement(31198..31683)
                     /locus_tag="JAM15_04860"
     CDS             complement(31198..31683)
                     /locus_tag="JAM15_04860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797592.1"
                     /translation="MSKSELTAETTEEMLEVLSGKDYDIACHLHELGKSLDCKIEPKT
                     GARSYKIVYSTKKPKRSLFTIECNEKKWRVKANLFHLNTYKDAVEECSKTIKDSITKT
                     RTCKKCNSKCIGGSSFDLDGKSYLTCIGSGHYFANMEEMDWKNLEKLITKENNIMQES
                     V"
     gene            32534..32911
                     /locus_tag="JAM15_04865"
     CDS             32534..32911
                     /locus_tag="JAM15_04865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HAT6797593.1"
                     /translation="MSKVVIATEKAPGAIGPYSQAIQVGNIVSTSGQLPIDMKTGELV
                     SDPKEATKASLDNVKAILEQAGTSMDKIFKTTVFVKDLKDFNDINEVYATYFKENPPA
                     RSCVQVAQLPKDAVLEIEAMAVL"
     gene            33307..35112
                     /locus_tag="JAM15_04870"
     CDS             33307..35112
                     /locus_tag="JAM15_04870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAT6797594.1"
                     /translation="MLSKLKEFQQEMIKYTETVASVLDVDIEIVDDRLIRISGTGLYK
                     SKINESVVTEGFIYDNVIQTGQELVVLDICDNQLCIECSHYMKCLNKVIIAVPIKYNN
                     RTIGVIGAISTDKTKKVEISAKIDNYLKFVNHICDLISMKIEEHEASKNSSRKMDMMI
                     EIIENVEKGVIILDINSKISYINNIALKKLDIDKNIIENIVNIVSVESSSNGHELLEI
                     DIDNKIYNINAKIIPVYPYINQYDKIIIFDKTYINHKGHGKVNSGWGNSDIESIIGNS
                     EAMLKVKERTKKLAKSNSTVLITGESGTGKELIARAIHAEGSRWNKPFIAINCAAIPE
                     NLLESELFGYIKGAFSGASSGGKVGKFELANEGVIFLDEIGDLSMPLQAKLLRVLQER
                     KFARIGSNKLIDLDIRVIAATNKNLLKLVNEGKFRDDLYYRLNVIPINLPPLRERKDD
                     IEAIMMKFASKYSLELGIQLNKIEENVMNMLINYNWPGNIRELENAVEYMMNLVGDDG
                     IIYKDMLPLDILNYYNINGNICKNKDINIIFEDDIVGGIVENQERILSIKELELTYIN
                     KLLNKYGRDTKTKKKIAKDLGIGLATLYRKLEEEQ"
     gene            35189..35728
                     /locus_tag="JAM15_04875"
     CDS             35189..35728
                     /locus_tag="JAM15_04875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2'-5' RNA ligase family protein"
                     /protein_id="HAT6797595.1"
                     /translation="MQYAIELYYDKKTEKQLFDLSKKIADEKISTKYLEWKTRPHLTL
                     ACFNDVDEACCIDKLKGFAQNHKVIPAYIGSVGMFNDTKTVFVSPRMNSSMYQFQREL
                     YEVLQDFDSNGWEWYHPNRWVPHCTIALTGDDESEAFFRASDVLLREFKKISGEFVSI
                     GLVKITFPVEEIFTVNMNR"
     gene            36369..37583
                     /gene="dpaL"
                     /locus_tag="JAM15_04880"
     CDS             36369..37583
                     /gene="dpaL"
                     /locus_tag="JAM15_04880"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HAT6797596.1"
                     /translation="MREIKWKLNNLPKSEEKEKGIEFLRDEEIAKAKAFHESFPQYEK
                     TPLVKLDNLAKSLGVSGIYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLDTDISELGY
                     DKLTSKEIKDKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAKEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNYSSAFVSAPDWVSAKGMRILGNP
                     LRGDEKVISGESGAVTTGALVSILESEDLKDLREALKLDENSKVLLISTEGDTDPDKY
                     RDIVWNGECQSK"
     gene            37933..39120
                     /locus_tag="JAM15_04885"
     CDS             37933..39120
                     /locus_tag="JAM15_04885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgeY family selenium metabolism-linked
                     hydrolase"
                     /protein_id="HAT6797597.1"
                     /translation="MLNETRKKQLTEVCQDLIRNASYSGQEENVVKAIEENFALLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEARIVDGKIYGRG
                     TSDMKGQVSAMMAAVSYFAEDTNKDFEGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKGINAVYKMANVIQKIQQLVPPT
                     HPVLGDGILVLTDIKSSPYPGASVVPDYCKATFDRRLLVGETREGVLAPIQALLDEMM
                     KEDPELNAKVSYAVEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYKGLKEAGIDSE
                     ITQYSFCTNGSHYAGEAGIRTIGFGPSKENLAHTIDEYIELDQLFKGAEGYYGILKSV
                     YKK"
     gene            39136..40719
                     /locus_tag="JAM15_04890"
     CDS             39136..40719
                     /locus_tag="JAM15_04890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacylase"
                     /protein_id="HAT6797598.1"
                     /translation="MRTLIKHGLIVDGNKTPAYEGDILIENEKILKISQDLNEEADKV
                     IDAKGRVICPGFIDTHSHSDLVILVNPYNEVKIRQGITTEVLGQDGISMAPLPQEHIS
                     SWRKNLAGLDGESDEIDWKYETTENYLKMMDYNGVGLNETYLVPHGNVRMEAMGLEDR
                     PATKEEIQKMCEITERELKAGAIGLSTGLIYIPCAYSLTEEIIEMCKVVAKYDGVFVV
                     HQRSEADTILTSMEEIIEIGKQSGVKVHFSHFKVCGKANWKYIPQVIELLEKAEKEGI
                     RVSFDQYPYAAGSTMLGVVLPPWAHSGGTDKLIERLSDENERAKMKKDIANGIEGWDN
                     FIEFAGIDQIFVTSVKTEKNKDTIGKSLLEIGKMRGKDPLDATFDLLKEEENAVGMVD
                     FYGLEEHIIGFMKRDEQNVCTDGLLAGKPHPRAYGSFPKILGRYVRELNVLTIEEAVY
                     KMTKKAATSFSIKDRGELKEGYFADIVIFDKDTVSGCDDFINSMQYPTGIDYVIINGN
                     CVVEEGKYNKIKAGKVLKN"
     gene            40747..42075
                     /gene="ssnA"
                     /locus_tag="JAM15_04895"
     CDS             40747..42075
                     /gene="ssnA"
                     /locus_tag="JAM15_04895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative aminohydrolase SsnA"
                     /protein_id="HAT6797599.1"
                     /translation="MILVGNGRLISQDSLNPYMEDGCVVINDNLIEDIGTTEEMKAKY
                     PVHEFIDAGKKIIMPGLINSHMHIYSSFARGMAVPGKPSENFLEILNNLWWRLDKQLT
                     LEDTKYSAYATYIECIKNGVTTVYDHHASPNAIEGSLFTISDVAKDLGIRTCLCYEVS
                     DRDGGNTIQQGINENVNFIKYAQKDDTDMIKGMFGLHAAFTLSDDTLNKCASEMAGLD
                     TGYHVHVAEGLADLQYNVDKYGKRVLERFNDFGVLKEKTIAVHCIYISAEEISLLNKT
                     NTFVVHNPESNMGNAVGCSPAIELLKRGVTVGLGTDGYTSDMFESLKVANIIHKHHLK
                     DPRVGFEESQTMLFDNNRKIAKAYYKNDLGVLKKGAYADVIVVDYIPHTPLTENTIGG
                     HTIFGMSGRSVDTTIINGKVLMKDRKLINIDEESILAKSRELSQNLWNRI"
     gene            42274..43626
                     /locus_tag="JAM15_04900"
     CDS             42274..43626
                     /locus_tag="JAM15_04900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HAT6797600.1"
                     /translation="MSQDKSPKIAPVDERLPVSKSWVFSLQHVLAMCAGAVAVPMMIG
                     SAARLDHASIVFLINACLFMAGIGTLIQSVGIGNIVGAKIPVIEGTSFAAVAGMTAIA
                     SSYSDSQVAIQTVFGSVIVAGLFCILLAPVFEKLIRFFPSVVTGTVVMVIGISLFPVG
                     IKWITDNKLEAVEPNSLALALAVLAITLLSFKFLKGIWNSTAILVGIVLGTLLSMAVG
                     MADFSAVNGVGWLNLNVPLKFGMPRFEPSAILSLCLIMLVLMTESVGNMIAIHEMVDK
                     EVTGKNIKRGLFGDGISTALSGIFNSFPITPFGQNTGIVGLTGIKSRFIAVYAGVILL
                     VLGFLPKFAAIIGAIPKPVLGGVGFAMFGMVMVGGVKTLSKVKFDGTKNGVIVAVSVG
                     LSMIPLTNPDFYHNFPTWVQTIFHSGITTGSLSAVLLNIFFNELGSKKEKNNKVEEAK
                     "
     gene            43818..44927
                     /locus_tag="JAM15_04905"
     CDS             43818..44927
                     /locus_tag="JAM15_04905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HAT6797601.1"
                     /translation="MANLKVNLYGMEFLNPIMTAAGPGAKDGALCQEAAKGGAGAICT
                     KTISVLPADVPRPCMAKTNSGFLNTELWSELPKEQWIEEEYKKVKETGLPVIVSMGYS
                     AEQIAEVAPLVKPYADAVELSTHYVGTDVAPIVNALKAAKAVLDVPVFMKMSPHTDIQ
                     TIAKAVEEAGADGLVMINSFGPCMAIDVNTGYPIMGSKAGYGWLSGAPIRPLAIRCIY
                     EASQVVNIPIIGVGGITCGKDVAEMMMAGASAVQVCTEAILKGPSIYGKIAKELNEFL
                     DENGYADVNEIKGLTHKKMAARGFRTHSVAPVVDDNKCIKCKQCVTSCVYEALEVTDK
                     LNIDADKCFGCGLCVTRCPKGALSICYNQVEAMNE"
     gene            45210..46601
                     /gene="hydA"
                     /locus_tag="JAM15_04910"
     CDS             45210..46601
                     /gene="hydA"
                     /locus_tag="JAM15_04910"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HAT6797602.1"
                     /translation="MGIVLKGGKVVTSEKTYCADVRIEDEKIVDIGLDISKENDEMVD
                     VSDSYVIPGGIDTHTHFDLDTGVTKTADSFETGTKAAIVGGTTTILDFATQAKGCSLK
                     DGLEEWHEKAKDKSYSDYGFHMAITDWNDSVCNEMEDMVKEGVSSFKLYMAYKGSLQV
                     DDGVIFEALRKAEEIGGIIGFHCENGDIICELVDKAKSENNLSPKYHQLTRPAIMEAE
                     ATSRLMKIAEVANSKVYVVHLSCKESLEEVLKAKQRGVDVIVETCPQYLLLNDELYDL
                     DGFESAKYVMSPPLRNKENNEILWNAILDNQIDTIGTDHCSFNYKGQKELGINDFSKI
                     PNGSPGVEHRMSLLYTYGVCKNKISINKMVEVTSTNAAKLFGMYPNKGTIEIGSDADI
                     LVLNPNKKSKIEAKKQLQNVDYTPYEGYEVDCQIEHVYLRGKEVVRDGELICNTPSGR
                     YINRRLTKGAREW"
     gene            46595..49156
                     /gene="xdh"
                     /locus_tag="JAM15_04915"
     CDS             46595..49156
                     /gene="xdh"
                     /locus_tag="JAM15_04915"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010237976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium-dependent xanthine dehydrogenase"
                     /protein_id="HAT6797603.1"
                     /translation="MVEFILNGEKVVAKEGKKLLDFLREDMNITSVKNGCSEGACGTC
                     MVIIDGKATKACVFKTDKLAGKNITTIEGLSERERDVFAYSFASQGAVQCGFCIPGMV
                     ISSKALIDVNNNPTEDDIKKALKGNICRCTGYVKIIKAVDLAAKIFRENIDVPKVNCK
                     GLVGENLPRVDAVGKALGYSEYVDDMRIEGMIYGSAVRAKYPRALVKKIDIEEAKAYP
                     GVVAVLTAKDIPGTIKVGHLKKDWDTLIPEGEITRYLGDGIVLVAAETREALEEAKKL
                     VKIDYEELTPLSTTADALREDAPKIHETGNILVKEHLVRGNAKEKIENSKYVVTKRYT
                     TPATEHAFLEPECAVAGPYEEDGVIIYSTDQGVFATQHECADMLGLPYEKVRVINKMV
                     GGGFGGKEDMSVQHHAALLAYHTKRFVKVQLTRKESIIVHPKRHATEMEFTTACDENG
                     YLTGMKATIISDTGAYASLGGPVLQRLCTHAAGPYNYQDIDITGTAVYTNNPPGGAFR
                     GFGVTQSCFATECNLNLLAEMVGISPWEIRYKNAIRPGQVLPNGQFADEGTAMAETLE
                     AVKEEYEKHPRAGIACAMKNSGVGVGIPDVGRCRLVIKDGKVHIRTSASCIGQGLGTV
                     MTQVVCETASLLPENIVHEVPDTHLTPDSGNTTASRQTVFTGEATKVASNKLKEVLDS
                     GKTLLDLEGEEFYGEYESITDKMGCDKENPVSHVAYGYATQVVILDENGKLEKVVAAH
                     DVGRAINPISLEGQIEGGVVMGLGYALTEDYPVVNSVPTAKFGTLGLFKSTDIPEIQA
                     LIVEKNKDLLAYGAKGVGEICTVPTAPAVQNAYYVFDKEFRTELPLQNTPYSKKK"
     gene            49308..50654
                     /gene="rpoN"
                     /locus_tag="JAM15_04920"
     CDS             49308..50654
                     /gene="rpoN"
                     /locus_tag="JAM15_04920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HAT6797604.1"
                     /translation="MNFNNSLELTQSQKLIMTTQLKQSLSILNMSKLELEEEIKREAE
                     NNPLVEVEKSGEINWEEYIKDMDRSRRLDRTEISYNPDNEVNLENLVKYSSNLYEDLK
                     FQISLYKLTDKELEVCEYIIDSLDEDGYLRTEEKVIVDTLKIDEELFEKCLISVQQLE
                     PSGVGARSLSECLMIQMASLGIYNEILEEIVTKDLNLIANNKYKEISKKYNMSLQKCV
                     ELINIIKTLDPKPGRTCSVEKSVYIQPDVTVEKIDDEFIVYLNEKDSYQIRINSYYKD
                     ILKNSQSDESAKEFIKERLNSATGLMKNIESRKTTVLKIAEEIVKAQDEFLRKGTKYI
                     KPLKMKDIAEKLEFHESTISRGVNGKYMLTPFGVYEFRYFFSSAIETENNEMASSTSI
                     KKIIKETIKDENKKKPLSDDHISKLLKEKGINVARRTVAKYREELGIPSSSKRKEY"
     gene            51432..52454
                     /locus_tag="JAM15_04925"
     CDS             51432..52454
                     /locus_tag="JAM15_04925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAT6797605.1"
                     /translation="MKNLLEIQKKLIPQAIELMERRYSILRQISLSEPIGRRTLSNVL
                     EISERIIRSETEFLKEQGLIDVAVSGMTITKEGSDLLDKLKDIMSDIMGLSKLQDRVR
                     EKLGIKRVILVPGSCDENGSLLKDVTRYGCEYFLGILKDGDIVSITGGSTMLEFSNVI
                     KTDKRYPNSTIVPARGSMGTDVEMQSNNIVASISKKLHSNCKLLHIPDELDESAMKTL
                     SQVPEIKTTLEYIKRTDILVFSIGRADVMAKRRKLPEDKVDEILSKNAVGEAFGYYFN
                     KDGEIVYKLNTVGIDLETVKQVKETIAIFAGTEKVEALLAISNMHKNMVLVTDEESAY
                     KILSLL"
     gene            52514..53521
                     /gene="gap"
                     /locus_tag="JAM15_04930"
     CDS             52514..53521
                     /gene="gap"
                     /locus_tag="JAM15_04930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010074729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HAT6797606.1"
                     /translation="MVKVAINGFGRIGRLALRKMMEQQDKFEVVAINDLTDAKMLAHL
                     FKYDTAQGRFNGEIEVKEGAFVVNGKEIKVTAERNPADLPWAELGVDIVLECTGFFTS
                     KDKAEAHIQAGAKKVVISAPATGDLKTIVFNTNSDILDGSETVISGASCTTNCLAPMA
                     KVLNDKYGIEKGLMTTIHAYTNDQNTLDGPHPKGDLRRARAAAGNIVPNTTGAAKAIG
                     LVIPSLKGKLDGAAQRVPVVTGSITELVCTLGKNVTVEEINAAMKEASNESFGYTEEM
                     LVSSDIIGISYGSLFDATQTKVMEVDGKQLVKVVSWYDNEMSYTSQLIRTLGYFAQLA
                     K"
     gene            53743..54945
                     /locus_tag="JAM15_04935"
     CDS             53743..54945
                     /locus_tag="JAM15_04935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018591751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HAT6797607.1"
                     /translation="MSMLNKKTIEDIDVCGKKVLVRCDFNVPLQDGVITDENRLNGAL
                     PTIQYLISKGAKVILCSHLGKPKGEAKPELSLAPVAKRLSEMLGKEVVFAADDNVVGE
                     NAKKATEKMENGDVVLLENTRYRKEETKNEENFSKELASLAEIFVNDAFGTAHRAHCS
                     TVGAGEFLQERVCGYLIQKELKFLGEAVANPVRPFTAILGGAKVSDKLAVINELLEKV
                     DNLIIGGGMAYTFLKAQGYEVGTSLLEIDKVEYAKEMMEKAKNKGVNLLLPVDVVMAD
                     HFAPDATPIVTEDANVKEDYMGLDMGPKTIANFVKTIKESKTVVWNGPMGVFEFENFA
                     NGTLSVARAMAELTDATTVIGGGDSAAAVNQLGFGDKMTHVSTGGGASLEFLEGKELP
                     GIAALDNK"
     gene            54971..55714
                     /locus_tag="JAM15_04940"
     CDS             54971..55714
                     /locus_tag="JAM15_04940"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007791163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HAT6797608.1"
                     /translation="MRKPIIAGNWKMHKTIKEALEFVNEVKDKVNSDKVEAVICAPFT
                     LLKDLKEATKGTNIKIGAQNMHFEEKGAFTGEVSPLMLKEIDMDYVVIGHSERRQYFN
                     ETDETVNKKVLKALEVGIDPILCVGETLEQREAGKTKDVCKVQVEKALENVLKDDLAK
                     VVVAYEPIWAIGTGKTATAEDANDVISYIREVIKGLYGELANEVRIQYGGSVKPSNVA
                     EIMGQSDIDGALVGGASLASNDYLDLVNF"
     gene            55726..57255
                     /locus_tag="JAM15_04945"
     CDS             55726..57255
                     /locus_tag="JAM15_04945"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HAT6797609.1"
                     /translation="MKKPVALIIMDGFGYNKDVKGNAIAESKTPNLDRIKKEYPNTLI
                     NASGLDVGLPDGQMGNSEVGHTNIGAGRIVYQDLTRITKSIKDGDFFTNKVLCEAMDN
                     AKENSLHVMGLLSDGGVHSHIDHLKAIIKMAKDKGVQKVYVHAFTDGRDTDPQSALEY
                     AKEVQASMDEIGVGEFATVSGRYYAMDRDKRWERVELAYNAMVRGIGEKANSIEEAIQ
                     NSYDDGKNDEFIMPTVIMKDDKPVGSIKENDSIIFFNFRPDRARQITRALVCEEFDGF
                     KREDIKNFFVCLTEYDITIENVHIAFGPQSLANTLGEYLAKNGKTQLRAAETEKYAHV
                     TFFFNGGVEEPNKGEERLLIPSPKVATYDLKPEMSAYELTDKALDKLGEDKFDFIVLN
                     FANPDMVGHTGSIEAAIKAVETVDTCVGKLIDKIVELGGSAIITADHGNAEYMLDPET
                     GKTVTAHSINPVPFIVVGQEYESAKLLDGGRLSDIAPTVLDMMKLEKPEEMTGHSLIS
                     K"
BASE COUNT        21882 a         6798 c        10061 g        18734 t
ORIGIN      
        1 ataaaatgat aattaaactt aacagtaata aataatgtga gaaatattca aatttaatta
       61 aataaagtgt cagaaatttg tttaaatttt agtattttaa cgattctgac cttttttctt
      121 atttttatgg agagtatcga ggatggagtc tctaatagtt acttttttgt gtctacttgc
      181 aagtttgatt aaaaaatggc tatacacact tgtgacttca gtcatgggag gttcagatta
      241 taatcttaat atataatttg tgaaataatt tgatgacgat ttgctgatgt ataaacaata
      301 aagattaact acattaaaat ttaaatcttg ttaagtaaaa cttataaaag gagagagatg
      361 gatgataaat gatattctaa ccttattatc tgaaagaagt gattttttta taaagctatc
      421 catagaacat ttgatgattt ctattatttc tataataatt gcgattgttt tgggtggtat
      481 aattggtatt attgtaagtg aatttcataa ttcttctaaa cctatattgg gaactatcaa
      541 ttttctatac accattccat ctatttctat gctaggattt ctgataccat tttccggaat
      601 tggaaatact actgctgtta ttgcacttac catttatgca ttattgccaa tggttagaaa
      661 tacatatact ggaattacta atgtggataa aaatattctt gaagcagcta ggggaatggg
      721 cagtacagat tttcagatat tgtataaaat aaaacttcca ttagccctac ctgttattat
      781 gtctggtatt agaaatatgg tgattatgac aattgcatta gctggtatcg cttcatttat
      841 aggtgctgga ggcctaggtg tagccatata tagaggaatc acgacaaata acacagcaat
      901 gacaattagt ggaagtatac ttattgctct attagcttta atatttgatt ttattttagg
      961 gctggtagaa aaattttttc aacgaaaaag aaaaaagaaa aataggaaaa aagtttttgc
     1021 cattctagga agccttattc ttatagcaac tatctttacg tcttatttat ttaatccttc
     1081 aaagactcaa actattcata ttgctactaa acctatgact gaacaatata ttcttggtga
     1141 gatgttggat attttaattg aaaaaaacac aggtctaaac gtggaaatta cacaaggcgt
     1201 aggaggggga acatctaata tccagccagc tatgaagaat ggagaatttg acatttatcc
     1261 agagtataca ggtacaggct ggaatatggt acttaagaaa aatgaattat atactgaaag
     1321 tatgtttagt aaactacagt cggaatacaa aactaaactt aaaatgcaat ggactggtat
     1381 gtatggtttt tctaatagct atgcattagc agttagaaaa gaagttgcag ataaatataa
     1441 tttaaaaaat atatcagact taaaaaatgt atcttctaaa ttgacatttg gagctgaata
     1501 tgacttttat gagagagagg atggatatac tccattgtgt aatacatatg gactgaactt
     1561 taaagataca gttgatttag atattggatt aaaataccaa gctatcaatg aaggtaagat
     1621 tgacgtaatg cctatattta caactgatgg tcagtatagt gtttcagatg ttatagttct
     1681 aaaagatgat aaaaatttct acccatctta tcaatgtgga aatgttgttc gtttggaagt
     1741 attagaggaa aatccagaac tatcagaggt atttaagatg gttggagata ttttgactga
     1801 taaagaaatg gctaaaatga attatgacgt agaaaacaac aatttagaac ctagagaagt
     1861 tgcttgtgag tttctgaata agaaaggtct tttataaatt ggaggaaata taatgacacc
     1921 tattatacaa tttaaaaata ttaaaaaaca atataatgat aaaactataa tagataatct
     1981 taatttagat atagaaaaag gagagttttt gactgtaatt ggttcgtctg gttctggtaa
     2041 gacaacactc ttaaaaatga ttaatggtct gattttgcca gatggaggaa atattttgat
     2101 aaaccaaaca gatatcaaaa acgaggactt aattaaatta agaagaagaa taggatattg
     2161 tgtacaagga agtgttcttt ttcctcatat gactgttgaa gaaaatattt catatgtacc
     2221 aaatctccta agtaaaaaga ataaattaga agtaaaaagt gctgtaaaca agtggatgga
     2281 aatagtggga ttgccaaatg atatgaaagt gcgttaccca tcagaattgt caggtggtca
     2341 gcaacaacgt gtagggattg caagagcttt agcttcttct ccagaaattt tattaatgga
     2401 tgaacctttt ggtgcagttg atgagattac acgaaagcaa ttacaaaaag agataaaaga
     2461 aattcataaa aaaacaggag ttacgattat ctttattacg catgatattt atgaagcttt
     2521 gattttggga acaaagactt tggtattaaa tcatggagtt gttcaacagt atgatactcc
     2581 tgagaatatt ttaaatactc ctgctaacca atttgtagac cagttattga atataagaaa
     2641 atctataata gatgatgata atttaaaaga ataaatttaa atttaaaatc aaattgttgt
     2701 gataaaaact attgatttag agctaacttc aagttgtata cttgaagtgg aaaagttaga
     2761 ttaaggtata gaagagaatt tagcagttgg ctgtagacga ggtaactgct gaaggtgctt
     2821 tcaataaatg gctagaacct gtatctattg aagattataa taaattgaaa taagaagctc
     2881 aatatacaga gtagataggc acttcaaata gaagtgtctt ttgtgtgcca taaaataaat
     2941 caaaatatta gcaaagaatg tgaaaaacaa aataaaataa tatgctatct ttaaaatagg
     3001 aggggtgcta tatggataac aatttaatta ccattgaaaa aactttagat tatatagaaa
     3061 aacatctttt agatgagatg ttagatttaa atgtaatttc taaagagata ggctattcaa
     3121 agtaccattt acatagaatg tttacatcag ttgtcggatt tagtatacat aattatatac
     3181 aaagacgtag actaactgaa gcagcaagaa tgctcatttt tacagaaaaa ccaattattg
     3241 aaattgcttt aatctcgggg tatgacacac aacgttcttt ttcaacaggg tttaaaaaaa
     3301 tgtttaagca tagccctaag ttttttagaa aacatcaaga ttttttacca ctacaattaa
     3361 aatttgatat taataataga aaaaggttac atggaggtat ggttttagat gttaaaaaag
     3421 ttaattgtac agatataaat attgttggct attctggtaa agtaaaaaaa ggatttcatg
     3481 ttattggaaa atgttggagg gatttgcata aaaataaaga gttgatagaa aacaaggtag
     3541 acttggattt tttaattgga gttaatgatt atagtaattt taaagaaatt gaaaataatc
     3601 ctacatttac atatattgca ggtgttcaag tagctacttt tggtaaatta cctaatggaa
     3661 tggaaaaatt cgtattaccg aaaagtaatt atattgtttt tacttttatt gggaaaaatg
     3721 aggatagtat gcaaaatgtt gtagaatata tctatcaaga atggttcctt aattcaagtt
     3781 gccagtttaa tgaaaataat ttatatgatt ttgtaaaata cggagaaaaa actgataaga
     3841 atggtttgag tgaaattcag ttttgggttc caatcattta aaagaaggga ttatgtataa
     3901 agtaggtgga tttatatagg caaagtttta taaaagtatg tatttataaa taatttatag
     3961 tctgtaggaa agaaatagtt ttactataag attatgataa aatacacaat actatgataa
     4021 aatagtacta aataatagat ttaattttgc aaaggataaa gtgttttaat aaaaatgaat
     4081 gtagaaaacg aattacttaa aaacctagat agattgcata caacagagtt aggcgttgta
     4141 agaattaaga aaaatctttc tttggagaca aatgatgtag tgaactggtg taaaactaaa
     4201 atagaatctc caaatgccat tattaataga aagggaaaaa actggtatat aagtgtatat
     4261 gattgtatta taacagtaaa cgctcacagt tatacaatta ttacagctca taaagaaaag
     4321 aaatgaattg aaaaatacaa aggtcaaaag cattttccac tgtttgtagt acctatgaag
     4381 aagtatataa aataatatta cttttgaata ataatttaaa ttttggaggt tgaaaaaatg
     4441 aataatactg taaaagaaaa attggcagag tcactaactt ctgatactac tgatatttta
     4501 ccttatttgc cttatttatt acaagatttt tgggaattag gaagttcacc agaacaaatg
     4561 ttacaattat ttagaaagca tatacctttt aatgaggata caaaagtttt ggatttagct
     4621 tgtggaaaag gtgctgtatc tgtgaagctt gcaaaagagt tgaatataca tatcaaaggt
     4681 attgatttga tacctgaatt tattgattat gcgagaagaa aggctattga atataaggtt
     4741 gatgctttgt gtgattttga aatgaatgat gctaatagtt ctgtaaaaat tgagcacgat
     4801 tatgattgtg tgatttttgg agctgtaggg gatattttag gtaattataa agaaactata
     4861 agtaagctat tacctacaat aaaaagtaag gggttcattt taattgatga tgcatatgta
     4921 gtagataaat ctacaaatga acagcttaat tttgagaggg tgtatcccac ttacaatgag
     4981 tggtgtatat tgttcaaaga attaggtctg aaactaattg aatgtatacc atgtttagaa
     5041 cttgaaaatg atgttgaaga ggaaatgaac tggattataa ctcgtgcaaa tgagctaatt
     5101 aaaaaatatc cttctcaaaa agatatgttt gaacaatatg ttattagcca aaaaaatgaa
     5161 tatactgatt tacagcagga ccttgttgga gcaacttgga ttttacaaaa agaataagat
     5221 aaatattaga ctagataatc aatgttatag tgaattatcc catgtctagt gaatataaat
     5281 aacataaaaa accgtcaaga tgaatagttt attcgtgctt gacggttttt agtatttgtt
     5341 gaagtaaaat tttatttctt tagtatatca cttttagtca atccatttga tttagcttga
     5401 gtattccatt gatgattccc cataagttta tataggaatc tagggaagtt aggtgaaata
     5461 aaaatagtac ttttgttgga atcatctata tgtatattat cactaagtat attttttgaa
     5521 agttctttta atgcaattcc taaatctttt ttaggtcctt tacccaaagg tacggattct
     5581 agtgaaccaa acatctcccc agctccaatt ccaatacctt gaacccatgt aaagttgatt
     5641 tttttacacc aatgctctat catttgaatt gccaaatgat tatgttcacc ttcattgaat
     5701 ccacagttaa ctattgcata cacaggaata ggttttttat tttgtgtttt taaaaatttt
     5761 tcacacttct ctaaaaaatg aagtaaatga gatggaatac catctacata aagaggaaat
     5821 gctattatta atctatcaca attaagtatg gcattaagag cgtcaggata cttagatgtg
     5881 ctatctactt taaatgtaaa aactttatta tcattttgaa taagttgttt taattcagat
     5941 aaaaaatact gtgaattatt tttatttact tttggactgc catttatcat tactatattc
     6001 atatggattc acctcttata tcttgtatat tttcatagaa acaaacagag tgttctttta
     6061 tattgaaatt tatagcattt ccatttacta atttcgtagc agtttctttt tcagcttctg
     6121 taatacaatc tccatagaat atagctttta aatttatctg tttatcatat ctgcttttat
     6181 gacgcatcat attatctttt attacaaagt atggaagaat ataattaatg cttttatcaa
     6241 gtacgttttt gacaaaaggg ctaaaccctc cgtaacagca tctgcttatt ataataattc
     6301 catcagagtc atttataagt ttacccatgt tgctgtaata atcttttaca acacattcag
     6361 aaggagtttt aatccagcaa ccaaaacaac caatacattt gtggatttct tttgtgtttg
     6421 gaagtatttt tatattgtca tcaagtttgg gtaataactt ttctaattct ttgtcagtta
     6481 aatcatgtat taaaagcctc ataaagtcca tctcctttta ttatgtatgt ttacttctaa
     6541 aaattatatc ttatagattt ttcagtaaat ctttacacca attaataaca aaattataat
     6601 agtcaactcc ataaatcatt gttgcataca tatatgtata ttggtcaaca caatgatttt
     6661 cttctgcatc atttttttgt ttacttaatt tatttagaag taattctact tcagttatta
     6721 acatttttaa gtttgtttca attatttctt tgggtagata cttgtaaaag aatatattaa
     6781 caaggtggtc ttgctttgtt ttagaaaaat ttataggttt ctttaaccat tcaagaaata
     6841 cttctttacc agtattagtt atggaatata gtttttttaa tttgttacca tctataactt
     6901 cgtgatagtg tatatatcct tttgtttcta atcttttaag tgcaggatag atacttccaa
     6961 agctggcgtc aaaaaagtac gaggtacttt ctgacattat ttgttttaag tcgtatccac
     7021 ttaattcttt ttccattaaa aatcctaaaa taatgtattc taacatatta cctcctggta
     7081 tcaatcagat atatatcgat tcgatatatt tattattaca gataataaat cttacgtcaa
     7141 gatgcttttt aaaataagct aaaaagaatt aggagttatt gataaatatg caaaaaaatt
     7201 aatataaaag gtaattaaat atcaatgaag atttaaaaat agttaaatca aagtaagagt
     7261 ctaatatata aaatttatag taactttatg gtttaaatat aaacttgtgt gctattgaca
     7321 aagtataaaa ttagcagtaa aataattgca tgagcaaata gattattgcg aacgcaaaaa
     7381 aatgaggaca atagatatta aaggagagaa tatgagagag ctattaaaat gggtttccat
     7441 tataaataga tacaatacaa attatattga caggaaattg gcggatattg gaatcaataa
     7501 tagccaatat ttttatgtat tacacatatg taataatcca ggtattacac aggacactat
     7561 atttgagaaa attcttgtga atcctagtaa tataacaaga gctttggcaa atttagaaaa
     7621 agaaggcttt ataacaagag aaccaggtgt aaaggataaa agaacatggc atttatatcc
     7681 tacagaaaaa tctttagaat gttatgatga aatactaaaa ataacaaatg ggtatgttga
     7741 ggagttgttg agttcatttg agaaagaaga gcaagagttg tttatgtcaa tgttaaagaa
     7801 agttgcattt ttagctattg atatgaatga agaagcaaaa ttggaggcga aggaaaatgg
     7861 aagaaaaata taaggagccg ttggaatatg aaaaggtttc aaagttatta actaagtacg
     7921 caattcctag tattatagca atgttagtaa gtgctttata taacattgtt gaccaaatat
     7981 ttattgggca aggtgttggt gtattgggta atgctgctac aaatgtcact tttccactaa
     8041 caacaatatg tactgcaatt gcattattat taggaattgg aggagcgtct aagtgttcat
     8101 tggaattagg tgctaaaaat tcagaaaaag ctacaaaagc agcaggaaat tctatatgct
     8161 tgatggctgt ttttggaata agtttattta tagtagtatc aatattttta acaccactat
     8221 taaaattctt tggctctaca tcagaaatac taccttatgc acacacatat acaaaaatta
     8281 catcaattgg attaccattt cttataatgt ccactggaat gagtaagttg atacttgcag
     8341 atgggagacc aaaagcttct atgttttgta tgttaatagg agcagttatt aatacaatat
     8401 tgaatccatt attcattttt gtttttaata tgggaattgc tgggtctgct ttagcaactg
     8461 ttattgggca acttatatct tttggaataa gtgttcatta tataaagaat tttcaacata
     8521 ttaaattaca taagaaaagt tttaaattag atagtataat ttataaacat atatttgcgc
     8581 taggttcaag ctcatgtttt aatcaattag caatgactgt aacacagata gttatgaata
     8641 atacattggc atattatggg gctaggtcag tttatggaag tgagattcca cttgcttgtg
     8701 tcggtatcat tattaaagta aatatgattt ttatatctat aattattggt atatcacaag
     8761 gtatgcaacc aattataggg tataattatg gggctgaaaa gtataatcgt gtaaaagaag
     8821 catataagtt tgcagtggga agtgcaacta ttatatctgt tattgcattc ttatgtttcc
     8881 aattcttccc aagacaaatt acgtctatat ttggtaacgg aaatgagact tattttatat
     8941 ttgcagaaca ttattttaga actttcttgt tcttaacatt tataaatggt gttcaaatag
     9001 tatcatcaac tttttttaca tcaattggga aatcagtgtt gggacttttt acttctttga
     9061 ctcgtcaaat tttattttta attccattga tagtaatttt accaatgttt atgggaattg
     9121 atggagtaat gtttgcagga ccaatagcag atgcagcagc ggcaatggta tgtatatact
     9181 ttgcagttca tgaaatgaaa tccttgacta taaagcaaaa taatttgatg agtaaccata
     9241 ataagattgc agaggtataa gacaatattt aagaagtata gaaaattaat ttaagaaata
     9301 taataaacta atttaggaag tgtagaaaat taatttaaag aagtataata aactaattta
     9361 ggaagtgtag aaaattaatt taaagaagta taataaacta atttaggaag tatagaaaat
     9421 taatctaaag aagtgtaata aactaattta ggaagtatag aaaattaatt taaagaagta
     9481 taatgaacta atttaggaag tatagaaaat taatttaaag aagtatagaa aattaatcta
     9541 aagaagtata ataaactaat ttaggaagta tagaaagcta atctaaagaa gtataataaa
     9601 ctaatttagg aagtatagaa aattaatcta aagaaataca atacattaat ttttaagtaa
     9661 cattaaatta atgtaagtaa aataatgttc atatgaagat ttaaaggtgc attttctgaa
     9721 gctaagtata tgttatgtct ctctatccgg tgaagtttaa tagctcaaga aaatgcacta
     9781 tttatgatga ttattttgtt ttatttccaa ttttggaaat aactattcta attaaatcta
     9841 aaattatacc ataaataaga aaagaaagta tagatgctat gtaccaataa atcgaaattg
     9901 accctgtaat tgttctacat gggatttgca tgcctgaatc cataaaaaca aaaaaactat
     9961 caatggtaga aataatagac aaaataggat ttaatcctat tagaataata ctttttgagt
    10021 cttgaccaat ttggtgcata taaatctcaa ataatgcaat taaaaaaaac aaaatgtaaa
    10081 agatttaata atttttttca tcaaaatacc tgacctaata taaattctgt ttgcactatt
    10141 tgcttactat aactatttat ctccattcag tcacatcact taattgtaat ctaggtcttc
    10201 ttgatggttc ttcgtcagga taacctaaag atattgctgc cactaattga ctatctgtat
    10261 ttaaccattc acataattca cgatatgcaa agtatacatc acaaatccaa agactaccta
    10321 gacctaattc cacagctgta agcgacatat tctgaattgc agctccaatt gattgcatgt
    10381 ttgccatttc atagaatcgt tcttcagggg atagcttttc taaaggtgat ttacctaata
    10441 tatttaaaat aaaaattgtt actggagctt gtttcatgat ttcaactgtg taatttgcac
    10501 cagcgatatg ttgacgactt cctggaagaa gcccattatc attaatttca ttttgaatac
    10561 ctttgctcat ggctttaagc atagattctt tttccttttc agtgatgaca acaaaacgcc
    10621 atggttgcct gtttttagat gaaggtgcat ttattccagc ttcaattatt ttctctatag
    10681 tttcatgtga aatgctttga tttttatatt ttctgatact tcgtcttttt gatatagaat
    10741 cacttatcat tttaagtaac ctccgtttat tttttggaaa aatctattta ttttctattt
    10801 ttaattattt tagcattaat cagaaaaaaa gtcattgatt ttagtataca attattaatg
    10861 attatattaa ggattgtatc aaaaagtatg tgattatact aagggattat attagacatt
    10921 atatttaaaa ttgtatgaaa ggttgtattt aatattatat taagagagat atatattagg
    10981 atttatatat attaagattt attatattga gcccttatat taaattaagg attataattt
    11041 aaaaataagc tataaaaacc caatattgtt ttgttcagag ataaaaaaga atactttagg
    11101 tgatttttat taaaaattaa gagtgataag attatatact ttataaatgt aaatatgacg
    11161 aataaaaatg ataaatataa taatctatat atttacatta ggagttttct atactataat
    11221 tatttatatt taaaactaaa tataaatgtt ggaattattt aggatttgaa attgtctaaa
    11281 gataaatata agtgatgaag aggtgatgtg atgagattag atatggatag tatgttatat
    11341 gtactaattt atatgacatt attggtatct atcattggaa gtatatttta tttttgtaaa
    11401 gacctcttaa atcataaaat taagtatgtt ttaataagag acatatttgt aaatagaatt
    11461 acatattctg aagaacggtt gcctaaacag tatatagttt ttcagaaata tgatatttgg
    11521 aggtattgta gtttgtttta atttgaaatg aatctattat aaattctaaa gtttaaaaat
    11581 aaaaaggaga gaataaaatg gatttcattt caagtatatt gcaaggatta ttaagtatat
    11641 tatttaattt tacaggtgat tttggaattt ctattgtact tataacttta atagttaaat
    11701 tagtacttat gccactatca ttaaaacaaa gattttctgt aaaaaaacag caagaattag
    11761 ctgaaaaaat ggaacatata aaagaaaagt ataagaatga tactaaagaa ttggaaaagc
    11821 aaatacaagt aagttctgta gaaagtatga agagtatgct gggatgtctt atagttttgg
    11881 ttcaaatgcc agtagtatat gctttatatc atgtatgttt agatatgaca aaggaattta
    11941 caacaattat aattccatgg attgctaatt taggtacatt tgataatttg tttatattac
    12001 cttgtatata tacattaatt atgttagctt caaatttagt gaattatata ccatatttaa
    12061 aaataaattc tcaagtaaag tttaacaaac aaatggctgt ggtgactatc ataacaagtc
    12121 ttatactaac tgttagaact ccagtagcca taggtctgta ctttataaca agtgcaattt
    12181 attcattaat tgaagatatt tgttttagaa tgtattttaa tcgaaaaaat agaatagtga
    12241 caaaataata taattattat tagaaatatt ttagcctgct aacatagaaa aagttagtag
    12301 gctattttta tctatgatat caattccatt aagaatagtc taaaaaatac tatcaaaatg
    12361 ctataaaaaa tactataaaa atactataaa aaaatagttg aaaaataaat aaattaatat
    12421 aaactaaaat aaagcctaca aaaaagaggt gataaataga aatggctaaa atactagttg
    12481 tagaagatga aaaaaggatg caaagtatta ttgtagaata tatgcaaaag ggaggatata
    12541 cttgtataac tgctaatgat ggagtcgagg cacttacaat attaaagagc aacaatatag
    12601 atttaatgat attggatatt atgatgccgt atttagatgg attttcagtg tgtagagttt
    12661 cacgtgaaat gactaatata cctattatta tattgacagc taaaggtgaa gaggaggaca
    12721 aattaaaggg ttatgaatat ggcgcagatg attatataac aaaaccattt agcccaaaag
    12781 tacttttagc aaaagttaat gccttgttac gtagatacac tactgatatt cccaaaaatt
    12841 cattgagttt aggaaagatt tttattatgg tagcatcaag gcaagtgtat gtagaagata
    12901 aattgattga tttaacatat aaagaatttg aattattgcg tttatttatg gaaaacccta
    12961 atcaagtttt ttccagagag aagcttttaa attgtatatg gggatatgat tttgaaggaa
    13021 acacacgaac tgtagataca catataaaaa ccttacgcaa aaagcttggt agtgaaggac
    13081 accatatagt tacattaatt cgttcaggat ataagtttga ggttaaggaa tgaatagttt
    13141 aagaaagatt atagaaaaac tgaaaaatgt agatatttca aattggatta aacaaaattt
    13201 tggactatat tcagttagaa aaaaagtgtt tttactttct aaattatcag gagcgttaat
    13261 tatattattt tatctggttg ttgaagaatt ttcgataaac tctaaatttg aattttggat
    13321 ttggtttata atactggtta tatttattat gagtattgat tttttattgg gaaaatttat
    13381 ttcagaacca atcacatcta taaataaatc tgcaaaaagt atgtcccaac ttgatttttc
    13441 taatccatgt actgtaaata ctaatgatga atttggagaa ctttctagga gcctgaatac
    13501 aatgtctaca aatctacaac aggcattatc agacctagaa agtgcaaata ttcaacttga
    13561 aaaggatgta aataaggaaa gaatgctatt ggaacaaaga aaggagttgg tagatgcaat
    13621 ttcacatgaa atgaagactc cacttggcat tatacgtgcg tatacagagg ggcttatgga
    13681 tgaagttgat gaagaaaaaa agaaaaatta tatgaatgtt ataatagaag aaactgatag
    13741 aatgaacaat atgattgtat cattattaga cttatctgca ttggaagcag gagtttctaa
    13801 acttaaccca gagcgttttg attttataga gtttgttgaa actgtggcag gtcgtctttt
    13861 aattgatata ccagatgcca atttttattt tacatatgat ttgccagagt atgaagtttt
    13921 tgtagtggca gataaaatga gaatggaaca agtagtagag aatctaatta ttaatgcaaa
    13981 gaagcatgtt gtatataatg gtaatttaga tttatcgatt acatgtgaaa atggcttgct
    14041 tttatttgaa atttataatg atggtaggat tatagagcaa gatgagattt caaagatttg
    14101 gtctaagttt tatcgtagtg ttcaatctca gcgtaaagga ggttcaggtc tagggcttgc
    14161 aattgtttca caaatactta caatgcaagg gttagaatat ggagtgaata atcgtgatag
    14221 aggagtagag ttttatttta tgattccaat tgatgaataa tttagtatta atttataaat
    14281 tataagtatc tgatgtaaaa tatttttctt tgtatacgta agtatttaaa gagaataaaa
    14341 taaaaaaact taatgaaaaa gtctaataaa aagtttaata aaaagtttaa tgaaaagctt
    14401 aatgaaaagt cttgttttcc tgattaaaac aagatttttt attaagcttt ttattatttc
    14461 acttcgattt cacaagagag acactctgat ttcaccaaat agaaataaaa taggttaaat
    14521 aaattaaaaa atagaagcgt aattaaataa ggttacaagg gggagtactt atgaaatggt
    14581 atacatggtt gactattata ttgataatat tgctttctat tccgcttaaa attaaattta
    14641 taaaatggtg ggatagacga caaaaaaatg ataaaggagg ttatgataga tgataaaagt
    14701 aggagagtta aaattttctt atggaaaaga taaacagata ttgcatggac ttaaatttga
    14761 agtaaaagaa ggagaaatct ttggattcct tggacctaat ggttcaggaa aatccacaac
    14821 acagaaaatc ttaaatggcg ttttaaaagg ttacaatggg cacgtatccc tttttgggaa
    14881 ggaagttaaa gcatatacag agtctctata tcaaaagatt ggtgttttat ttgaatttcc
    14941 ttatttatat accaatttaa gtgcaattga taatttagaa tatttttcgt ctttttatcc
    15001 taaaaatcaa aggagagaca tatatgaact cttagatttg ttagagttta agaaagagtt
    15061 tataaataag cctgtatcat cctactcaaa aggtatgaag caacgtatta gcatggcaag
    15121 agcattggta agtaatccaa agttgttatt tttagatgag cctactagtg gacttgaccc
    15181 atctggagct gtactatttc gtaagattat tgaagaagaa cgaaaaaaag gaacaactat
    15241 ctttttgact actcataata tgctagatgc agatttaatg tgtaacaatg tggcttttat
    15301 tgcagatggc aagattatgg taatagataa acccaaaaat ttaaaaatga aaaatagcaa
    15361 taataaagtt gaagtggaat ttgtatataa tggaaatcga gatattgaaa ttgtagatat
    15421 acaagagtta gaatctggaa taacttttaa atatgatgaa atcttaagtg tacattcaaa
    15481 agaacctaca ctagaagaag tttttattaa atacacagga aggatgttag tgtaatgtat
    15541 tctaaatttt ttaccttagt aaaaaaagat ttttggatga tgatttatgg taaatttttt
    15601 gtgctgacac ttggctctct catactttat tcgtgttata ttaattttgg ttatgtaaag
    15661 tttatggatg aagatagtta tcacaataat gtatatctat ataatccaga gaatataagc
    15721 atgagtgcat ctccattaat taatcaagtt tcttctatag gtgaattaaa agcaaaactt
    15781 gatgaagata caagtgcagt ttgtattgat atgagttcca gtaagccgaa agtaatttta
    15841 catgaaagta ttaaaggagt tgacaattat agagctgact atgcattgtc attattatca
    15901 tcagaaaaag accataatag caaaatatca gacaacaatg caataattca aattaatgat
    15961 aaggatacat ctgagataaa acaaagaaaa gacatgactt gtgagatttt attctttgaa
    16021 attgtagcta ttggattttt agggattgcc tctttattat ttaaagaaaa gcagatggga
    16081 gtaatgcgta ttactggtat tttacctgta aaaagaagtc tttttatatt atcaaagata
    16141 tttgcttttt tgatatgtga cctatgtttt acagttcttt tagtagtatt taatattgga
    16201 ttttttgaag gagtaaaaat acttccacaa gtattagttc aagctagtat tttatcaatt
    16261 attatgtctt tgattggaat aggatgctca atgttattga gagattttaa gcaattttct
    16321 cttatatatc ttgtggttgc tgtattcata actacaccta tatttctatc tgcaaataca
    16381 tcttttgaaa tagattggat taaatatcat cccttctatc atgtttatag tcagcttaaa
    16441 aatgcgtttt tcatgaattt ttcaaaagaa ttagtttatt ttgtagtgtg ttctttgaca
    16501 ataatagttc tatttttact tgtaaaatat atttttaata aagagttggt tagggaggga
    16561 taatcttgat aggattacat taccagttaa agagtataaa aaaagataaa atgtgtataa
    16621 tttccttctt tttaccagtt gttatggcga ttttaataaa ttttatggga acaattgata
    16681 tatcttcatt aggagagata cgttttggta tagtgaagga tacacttcct gtacaaacag
    16741 agcagtggtt gaagaagtat ggtatggtaa gtgtatatga cacaaaaatg catttaatac
    16801 gtgaaattaa ggatattaaa acggacacaa ttggagttgt tagagatggt aaagggataa
    16861 aaactgtgct ttatggaaat gagattaatg ctataaaaaa tgttggaaaa acattgccag
    16921 agatgtttag actaaagggt gatttaaaag atgttgaggt tacaatattg cctaaagata
    16981 gtattttaaa agagtttcaa aatgttttta ttgctatgat tttaattact gctatgttta
    17041 tgggatgcac ctttaatgca atgaatatta tatcggaaaa agaagatgga atatcattta
    17101 taaatgaagt tttaccacag agtagaagtc agtatattat acaaaaagta tttttgggtc
    17161 ttttatgtgg gtgtttatct tcaatgataa ctgtatttat atgcttggat atttcaatat
    17221 tagatatgat aatgatgttg ttactcgttg tattttcagc atttatttca tcacttatag
    17281 gtttatttat tggaaagttg tcagaaggtc ttatggtagg aattgtttat attaaaatag
    17341 taatgatttt atttataggt actcctttgt taatatatct tctaggggtt aatacaagag
    17401 gtatagggaa tttatgctat ataatgccat cagttgctac atttaatggt attatggaga
    17461 ttattaatgg taatgtcatt attataaaag atattgtaat tttggttgta cattgtgtag
    17521 tatggtttat gatatatatt attttagata aaaaaagaaa gttatctttt agtagataac
    17581 tcagtataat tataattggg acaatttaat aggtgattta atatactttg tatagtgtaa
    17641 tttatgtagt gcaatttgta tactttaatt tatgtagtgt aatagttagt tttattttat
    17701 aattattcaa tataatttag taagaagttc agtacaatta gagctactta gtggaaaact
    17761 taataagtac ttaaactata taaatacttt attttcctcc atttgtacta taaatttaat
    17821 ttatgatata aatggaggta ttattatatg atttgataaa tttcatcatt ataacctaca
    17881 agtaaaggta ttattatata aagttaataa agatagtatc aaaatattat ttgctataaa
    17941 gagaggggct caaaataaag ataaacctat ttttcaatgt tgaaatgata aaatatattt
    18001 gatttcatat aaaaaatttt tttcataaat taaaaagtcc attttaagcc ccctcatttt
    18061 taaccagata aatcgagtta aactatttaa atatattact cggattcatt tgacttagat
    18121 attccttgct tgtaaaattg ttttgaatag gggatagcca aagcaaaaaa taaaagtata
    18181 atccctgcta tgattattaa attattaata gaaattacat ctgccattgg tccgaaaatc
    18241 atcataccaa gaggaataaa accagtatat ataataatag gtaagctaag aactcgacct
    18301 agcatttgtg gtgctacatg ctcttgcaac atagtcatag ctgatgcttg aataattgga
    18361 attgaaaaat tcgtaaaaaa cataaatata aaaaattgcc aagcttgtgt tacaagacct
    18421 agaataattg aaaaaatagt ataggataat attgctagaa aaaaggtctt atttctattt
    18481 ttaaaaccac caaaaactcc tataatcaat ccacctaaaa ccatacctaa aaatccaatc
    18541 atttcaataa tagacaggta tatataaccc ttgccaaatg ttcgttcaat aagaagtcct
    18601 ataagaaatc ctgatggaac acaaagaagc atgaatgctc cataagtgaa aagcactttt
    18661 ctaatgaact tatctgaaaa acagtacttt atccctgata ccatatctgc aaaaaatgag
    18721 actttttcag tttgttttgg tatattatgt ttaggaattt tgatgaatat caataataca
    18781 atagcaataa ttgcagtaaa tacatcaatt aaaagaactt gatttatttt attaccaaat
    18841 ccaagtattg cagcagctac aataggaact ataaattgta ctatagactg taaactacta
    18901 tttataccat taaaacgcat taaatgttct tctggtacaa gttgaggaat cattgcgttt
    18961 acagcaggtg tttgtacacc acctcctagt gaacgtataa cagatattac tgatatggct
    19021 attaattcac ttgttgtgcc atttgatgac atcataaata gaattagaac taatgtagat
    19081 atagcaattg ttgaatctga tacaattatg agtacctttc gattgtagta gtctgcccat
    19141 acaccagcaa aaaaagaaat tatcatttga ggtataaagg agcatacagt taaaactgtt
    19201 acccatacac ctgatgatgt ctgaagtgtg acataccata tcattgccat ttgtacaagt
    19261 gatgagccaa ataaggaaat atattgactt gctaaaaaaa gaatgacttt tttcttccat
    19321 gtagaattag tatttttatt ttccatccta ttcctccttt gatttgtgtg ttgaattttt
    19381 cttgctctta aggataacac acaaatcaaa gtctggagtt agagtggagg gctaggaaaa
    19441 ttgttttttc ataatttgaa gatgagattt catggttttt gcattatgtt cagcttcttt
    19501 caatgaagtt atcagtttgt cacacactga tataatttcg tcatcatctt ttggagtgtc
    19561 aaggacagtt ttaatattag tattaggatt agaagataaa gcatttaaca ttcgtaaaat
    19621 agctgaaaga gaatagtttg cacaacgaag tgcgcttata attttaagtc gctttatatc
    19681 ttcgtcagtg tatacgcgat aaccattttg ctttcttttt acttttaaca agccattcat
    19741 ttcccaattt cttaaagtat ctattgtaac atttaagtgt tctgcagttt cttttctagt
    19801 taaaaagagt ttatttgttt ctggagtatt tccatttaaa atctgtgtaa caatagtaag
    19861 tgcttcctcg gcattagatt tttctatttc taattgttgc aagtattgat ttacaagact
    19921 aatagcctta tcaaagtccc tatttgctga tgttcttaca atctcaaggg catcttttct
    19981 taatcctctt tgtaccactt caattttcaa ggctgtacga gcaaatctaa attgttctat
    20041 atgaaaatca ttaaagatac ggtaaccatt ggtattacgc ttaggtttag gtattaagtt
    20101 tagttcttca tataaacgta ctgtattagg atgtacacca attaaatctg ctacctttga
    20161 tgtcgtgtaa gtgtccatta gtattcaact ccttttagat atatagtatt agtcataata
    20221 acaccaaaca aaagtctggt gttatagtgg agggtttggt tatctaagag taattaagag
    20281 taattagttt atctaagagt gattaatcta ttatagaagt aagtatatat ttttcaataa
    20341 actcccatct atcacgaggt ttaaacacta ttttagatgg tatggctatt actaagtcat
    20401 attgtggaat acaacaaata gcatttcctc cagttcccat tgctgaatac cacaaaacac
    20461 catctttttt acatatccac cacagataac cgtattcatt actattcatt ttaaccgatt
    20521 cttcaatcca cgatttagat ataatacgtt tattattcca aataccatca tttaaataca
    20581 gaaaaccaaa tcgcaacata tctctagcac tcaatgtaag tccccagcca cctatagaat
    20641 aaccctgtct atcttttgcc caacccttaa gattttttcc aaagaaatct tcaaaactaa
    20701 aatctttcat atcataatct ggtataactt tcataccaat aggtttaaat aagtattcat
    20761 tagcaaattc acgagcagat tttccagtag tttttgttat aatagctgaa agtaggtgcg
    20821 ttccagctga agaatatttg aaagtaccaa tttcgccttt ttgaccaagt tgattcaagg
    20881 tatattttat ccaatctttt tgtttgcaaa gtctttctaa agactcagtc atatttttaa
    20941 aagggtatgg tgcagtcatt gtaagtaggt gacgtatagt tactgctttt ttacatattt
    21001 cagaaggact acaagtatat tcagggaaaa aatcaacaac cttttggtca acatctttta
    21061 tatatccttt atctattgca atacctatta aggctgatat aatacttttt gtaactgatg
    21121 caacatgaaa agtatcatca gcattatatc cattatagta cttttcaaag acaacttttc
    21181 cttttcttgc aataattatt ccatttatat tactatattg tgagattatt aaaggttcca
    21241 gttgtgagag cttttctgaa ctcatgccaa cacttgaagg gtctactttt tcaaatatta
    21301 aatctaagca attgttttta ttcattaaag atacctccct gttatagatt ttggattttc
    21361 ttttagagtt tttggagaac cttctgcaat tatataacct cctttgtcac caccttctgg
    21421 accaagctca acaatccagt cacaaacatt taatacatct atatcatgtt caacaacaat
    21481 tacagaattt ccattttcca ccaattcatc taataattga atcaacttag aagtatcata
    21541 tagacttaga ccagtagttg gctcatccaa tacataaagg atattaccat ttcgtttttt
    21601 accaatttct tttgcaagtt tgattctttg ggattcacca ccacttaaag tcggtgtagg
    21661 ttggcctaat tttatatacc ccatacctat ttgttctaat acatttaagt gtgaaacaat
    21721 atttggaata tccttgaaga aatgtacaga ttcagaaaca ctcatattta aaatatcatg
    21781 tatattttta tttttatatt taatagataa agattcatca ttaaatcttt ttccctgaca
    21841 ttcactgcat atatggtcta tacttagatt atttcctaac cagacctttt catatccact
    21901 accactacat ttaggacaag cacctttgga gttaaatgag aaatgaccag ctgtaaatcc
    21961 tcgttctaac gattctggct gacctgcaaa tagtgtacgt atcttatccc atataccaat
    22021 ataagaagca ggagttgagt tcatattttt gccaatagga gattgagata tctctgaata
    22081 tccagaaata tgtttagtac caatcagtct atctgcaata gtttcaacaa ctgcataatc
    22141 gtcttcctca cctatttcac tctctgaaga atttgtttga ttattgatag tatggttatt
    22201 aaattggctt ctaagaagag gaagtagggt gtctgatata agtgaactct tgccactacc
    22261 tgattttcca gatattccaa ccatagcacc caaaggtaat gatacagtta catttttaag
    22321 attatttgta tttgcatttt gaatagttat acaaggtatt ttatcagtat gtgtaatatt
    22381 tttattgctt gttctattag gcattggata ttttccagat agatactgcc cagtaagtga
    22441 tttgtcggat tgaagtagac cttctaaatc tccttgatat actaattgac caccttcaac
    22501 accagctttt ggaccaatat caataatatg ttctgccatt tcaattgtgt ttttatcgtg
    22561 ctcaactact atgaccgtat tgcctaaatc tttaagtttc tttattgatt ttaagatgtc
    22621 tattttttct gattcatgca atccagctgt tggttcatca agcacataaa ttaatgagtc
    22681 catctctgaa tcgagatgtg aatttaaaaa tagtctttgc atttccccac cactcaaagt
    22741 tgacatttct cggtataagg atagatgacc taatcgtgat tctattaaat gtcgagtttt
    22801 ggataaaata tcatttacaa gatttgtacc aaatgtgttt aaattacctt ggtttattaa
    22861 gattttaagg aaatcatcaa tttctaaaat cgtcattttt ccaagttctc caatatgttt
    22921 tccgtttaaa agtactctac gtgcttcttc accaatttta aaaccattgc aatctgaaca
    22981 ggcagtcata gtataaactc catttaaatc ctcacccctt ttgtaacgat tgtgaaatac
    23041 ctttgataaa gaggaacttt ttttaccatt ttcataatga ccatagagta cttcatttct
    23101 tatttcttca ggtagttgta agaattgtat gtctaaataa tcgttgaatt ttttagaaaa
    23161 tactctcaaa tatcctggtg taatctttgc tctatctaag acttgtttta gggtatcatg
    23221 cttatcaagg actaattttt caatagtaat ctcaaaatat gcaccatgtc cagagcactt
    23281 catacacatt ccatctgaag agttgtatga gaaataactt ggtcttaatc gttcttcctc
    23341 atacccacaa ttattgcaaa ttagattatc gcttacagga gtatcacaca tagtacacat
    23401 tatttgacct tccactgaat acaatagtgt aagcatgttg agaatattgg ttcttgtgcc
    23461 tactgttgaa cgaggattgc tctggcgaat aatattttgt tgaacagcta tagtgggagc
    23521 taaaccttga atattatcaa acttatcctc actatcaata cctgcaagta tacctaaaga
    23581 ttgcagatat tgtttacgcc cttcctcaaa tacaatgtca aacataaggc tagacttacc
    23641 tgagccactg acacctgttg caacaacaag cttatctttg gggatagaaa catctatatt
    23701 tttaagattg tgtatctttg ctccattaat ttttatttct ttcattggtt cacctcattt
    23761 tatcaatttt atcaaaccgt aaaataggga tatattaatc cttaatacaa gaatagatta
    23821 ggtgaggtta ttaaaaaggt tctataggta aatatatatc gaccaagtgt ctattttgag
    23881 ggtgattgtg tgggttgtta agatatactt caaaagggaa ggaggcacgt agcttataat
    23941 taccatttga tagccattca ttatacataa aatcccacgc atcactatat tcagattttg
    24001 aaatatcaaa atgccccaca agatattttc cagaaggtat tatcatattg ccaagattgt
    24061 cattctcttt gacaacaatg ttatctggaa tggtcatgca aatactagtc cttaattgat
    24121 gctcctgtgt aaattgtgga ttatcatgat aaatggctaa tatttgtgtg ttttcaagtc
    24181 caagtagatt ctgctcactt gcatatgtga ataaccgttc taaaagtttt gggaaagtac
    24241 tggttagatt accatatgaa ccagtatacc tagtgtaaat agtattcata ttatcaagtt
    24301 ctagaatttt aatttcacct ttaacctctc tagtattctt acatttaggt tttgatatgc
    24361 ttctattgta ctgagaaatt ttatatggtt ctttgcaatt cttgctataa ttgtttctat
    24421 attttatagg gcttatttta tagtaatttt taaatgctct cgagaaaact gctgaatcag
    24481 taaagccgaa gtagtgtgca atatcagtaa cagtcatgtc agttctatga ataagaaaag
    24541 cagttgcatt ttctagtttt agcctattta catattgtgc caaagtttct ttttctattg
    24601 ctttgaagat tctatgaaaa tgaaattttg aaaaacctgc tatattagaa agttcatcaa
    24661 gagaaagagg ttcatgtaaa tgttcttcta tatagtcttg cactttgcaa atacgattta
    24721 gatattcttt tttactttta gcatttgtca tatatagccc tccttattgt gtaaaatgtg
    24781 tatcaattaa tttatagcaa tatagtaata aaattttatg tttttgtaat ttatgataaa
    24841 taagatagcg tttaattttt tataattgat aaaagatatt tataattaat aaaagatata
    24901 agatgcctta tattgtcttt gcatataagt atagtcttcg taataattag tataccatag
    24961 tgatttattt ttaattgtgt atttatataa atacacaact tatgatatgg acgaattatt
    25021 atgcaaataa gctgtaatta aataaattgc aatataaacc agttgaaaca taagttaggg
    25081 aaatattatc aaagttatta tttagcataa gagtatagag ggaataaaat aagattaaaa
    25141 aattacatac taaatttaat aaaattatta tattaaaaat aatattaagt ttattgttta
    25201 aataaaaaag ttaaatctac actattaact tattatactt aaaactttaa aatgaaaata
    25261 tcaaagaata ctttttaata aaaataatca tttaataagt tatttaaaaa tctaaaaact
    25321 ttacaacaaa ttatctattt aaattggagg agtgggaata tgagtaatag tttttatcaa
    25381 ttaaattcag cagtattata ttttaatgaa aaaagagatg taactagaat aaggtttaat
    25441 cactatgtaa tgagaaaaga aaatatacaa agattaaaag gaactctgcc aagaggacaa
    25501 tttatgatga cagtaaggaa agctgcatct gaccttgatg tatctatatc tacaataagt
    25561 agacttgtaa atgaatttat agatttaggt atattgagat taataagtag gggagtaaag
    25621 ggaaattgtt gttctgtata tagttatgtt tgttctgaaa gtagtaatgc agaaattgta
    25681 acaaagaatg gtgatatttt caaaaatata gagaaataca ttgatgcaac tattaacaat
    25741 aaccaaaaaa caatgaaata taaacataga aatgagttgt ttaagaacag taataccaac
    25801 acatacagcc gtataaatca agagagtata gacaaagatt atgatttgat aattcatact
    25861 gggtatgaaa cagaaaatga gacaaagaaa aaagaattat taaaaaataa tttaaataaa
    25921 aagaatttaa ataaaaatac ctttgaaaat ttggatgaag atttgactga agattctact
    25981 tataaaaatc cagaaagcat acatgaaatt attataagaa aattaaatag tgaatcagga
    26041 aaaaatttta aagctgattt gagtataact aaggcactta tagataaaag attaaaagaa
    26101 gggtatagtt tagaagattt ttacaaggtt atagaggcaa aggtaagaag atggagatat
    26161 acagatatgg aaatatatat agaaccaaca attctgtttg ggtatgaatt tgagtcgtat
    26221 ttaaatgagg agagttcttt atctgcttgt aattatggtg atatgtgtta tgaagatatg
    26281 tattgagata tttattaaga tattagttgc tttttagttg tttaaaatat gtttatgtat
    26341 aaatagtgta ttaaaatgga gttgtctcaa aatagagaga agcctcttct taattgttta
    26401 aatgatgaaa atatatttga tttaatacaa aggagagtgc ctcatgagct agaaaattca
    26461 ttttgagacg ctcacttttt ttaattactg gagaaatata acccatttta caagagtgca
    26521 tagatatata taatggcata atgtggattt aaattaaaaa aaataaaata aagccataaa
    26581 tattgaaatt ttcaatattt atggctttat tgcttgtaat aattaataga atatatattt
    26641 tttattaatc atctatttca aattctaata ttttaccagt aattgcatta attgttatct
    26701 catattcagt ttttcctttt attatttcac cttcatattc tttgtcatct tcatcatact
    26761 taaattttac tattttccca ccaggcactt tatctagcat tattgattta gctttttcag
    26821 cactaataat agaactgttg tcattagtat tagagttatt cttatcatta tcatcaaagt
    26881 catcatcaga atcattgtcc atgtcaatat ctacaattct tccatcaaat gcacttatct
    26941 ctaattcata tgttttctta ttttttatta ctttagcctc atattcgtta tcttcagcat
    27001 catatttaca atagattaaa ttaccattag gaacagcatc taatgctata gacttagctt
    27061 tatccaatga tatattttgt gtacctaaat tattatcatt taagtcatca tctttttcaa
    27121 tttctattat tttaccagag taggcatcaa tttctatctc atataggata ttatccttta
    27181 taactttgca gtcatattca ttatcatctt catcataata acaaactaaa atattgcttc
    27241 ctggaagagc ttgttttaat atttctttag cctgtattaa agatattttt ttagttttat
    27301 ttcttatgtt cacatttttt agttttaaaa tatcttcaaa tgctttttga ttatatcctc
    27361 ctcctacttg tgttatttca tctatatctt tatttttaat aaattccttt tgactattta
    27421 caaggctacc attagatatc attataggag aattttcttt agcagctaat actcctattg
    27481 ataatgaatc tactaatgca ttttcttggt taataccatc tttagctaca aatacattat
    27541 ttattttttt atctttataa aatttatcaa taatttttgc attagtattg tttctatctg
    27601 aaccactgat tctttctctg tttggatatt tctttactgt attgtctgat aaaatcttat
    27661 ttcctccaac tatgtaagat ttttttatag acctattgtt taagaaattt atactactat
    27721 cattgctgtt ttcatctgat actaatatta taggcatatt atgtattgct gctggagaag
    27781 ctatactaac tgcatcagat aatcccttta gtccatttac aactgcaaca ttttctacct
    27841 tttttatctt atctatttct ttaagtacat ttgtagacat ttcatatata ttgtttccta
    27901 ctattttatt tatttttatg ttaagtgatt ttatttcatt ttctacttta gaagaaatgc
    27961 tatttccact atctacaatg tacacattat ctacaccaag ccttttaagc tcagccttag
    28021 ttgaattttc aatactgttg ttgtttacta aaagtatagg tgcattcttt agcttagcaa
    28081 atggatttgc acaaagcgca ctttgaatag aattaccatt aactataatg gctgtttttg
    28141 attgaaccca tcccaattta cttacttcta ccgctgtttc atatcttgtt ttacctatta
    28201 atctttcttg ctttgtagta ttgtctgcaa aaattgctga agaactagaa aaaaacatca
    28261 tacctgatat taatatagct aaatttttct tattcatatt tttacctcac aatctttaaa
    28321 aatttgttat ttagcatact taataaaata taatcttaaa atcaaattga tactgagttt
    28381 gaagttacaa aatcaaaaaa taagatttct ttaatacaaa attttccttt ttatatttaa
    28441 cattgtatca caaatataaa aaggaaaaaa ctttttaaaa ggggtataca ctattcattt
    28501 tttatcttat aaataagtct ttaccactgt tttatatatt ttaaaataga cacaagacct
    28561 atttctaaat cttttataaa tactttaggt gaaatttctt tttaaacata tctaaaaagt
    28621 atttgtagta atattaatgg actgaatttc ttaaagtata tatttctttg catgttggag
    28681 tttgtgaagt ttgagaattg gagggtgaaa gaaacatgca atggattaat attaaagaac
    28741 tgtattttta taatatttgt cttaaaaata aaaaaatcta ttgacttgaa gttaactcca
    28801 agtagtaaag tataattata caagaattat atacttgtaa gaatagttaa agtagagaga
    28861 aaaaacaaac aagttttaaa gggggaagta aaacaatgga ggcaaaaaaa ttaggatttg
    28921 gattaatgcg tttaccaata aaagatgaaa atgatgttac aactattgat atggaacatt
    28981 taaataaaat ggtagacact tttttagaaa ggggatttac atattttgat acagcctatg
    29041 tgtatcacat gggaaaaagt gagatagcac ttagagaatc tctagtaaaa agacacaaaa
    29101 gagagagttt tactatagct acaaaacttc cattaatggc tttaaagaaa aaagaagagc
    29161 aagaaaccat ttttaatgag caattagaaa aatgtggtgt agactatttt gactactatc
    29221 ttttacacaa tataggcgtg tcacattatg aagtagctaa aaaatttgat agctttaagt
    29281 ttattgaaga aaagaaaaaa gaaggaaaaa taaagaatat tggtttttct tttcatgata
    29341 gtgcagaact attggataaa gtcttgagtg agcatccaga agtagacttc gtgcaattac
    29401 agattaatta tttagattgg gataatgaaa gcatacaatc tagaaaatgc tacgaggtgg
    29461 cagagaagca taataagcct gtaattgtta tggagccagt aaaaggaggt acacttgcaa
    29521 agataccaga aaaagcagag aaattattga atgactacaa tccagatatg tcaatttcat
    29581 cttgggcaat acgttttgca gcaagtaaag ataatgttat gatggtctta agtgggatgt
    29641 caaatatgga acaattatta gacaatacag gatatatgca aaatttcaaa ccattcgtac
    29701 aagaggaata taatattata gatgaagcag tagagattat caacgaatca attttagttc
    29761 cttgtactgc ctgtcagtat tgtgtagaag gctgtccaaa aaatatcgct attccaaact
    29821 attttgcgct gtacaatgca gaaaaacaag ctcttaatac tggattttca acacagatgg
    29881 tttactataa taattatact aaaacttatg gaaaggcctc agattgtatt gaatgtaaac
    29941 aatgtgaaga aagctgtcct caacacatta aaattataga tgctttaaag aatgtagcag
    30001 aaacctttga gaaataattc aatctataca atatcaagag gagaagatat gtatgacgat
    30061 ttcagaagtt agtaaaaaat acgagctttc agcggatact ttacgatatt atgaacgaat
    30121 tggtttaata ccacctgtaa atagaaataa aagtggaatt aggtctttta cagaagaaga
    30181 ttgtgattgg gttaatttca taaagtgtat gagaggtgca ggtctttcta ttgagacatt
    30241 aattgagtat gtagctatgt ttcaacaagg gagcagtact atcaaagcta gaaaagaact
    30301 tttaatagag cagagaaacc aactagcaaa aagaatagaa gaaatgcaaa aaactttgga
    30361 acgattaaat tttaagattg atagatatga agaaggtatt gttgagaaag aaaaagtatt
    30421 aaagagcagt agaaataaga aaatggaggc agtatcttat gagtaaaaat gtattaatag
    30481 tatcagctag tcctagaaaa ggtggaaatt ctgacttatt gtgtgaacag tttatacaag
    30541 gggcattaga atctaaaaat caagtggaga aggtattttt aaaagataaa gatattaact
    30601 attgtactgg atgtggtgct tgttatgaaa aagaagcaag ttgttcacag acagatgaca
    30661 tgggagaaat tcttgagaaa atgattgagg cagatgtgat tgttttagcg actcccgttt
    30721 atttttatac tatgaatgcg caaatgaaaa ctatgattga tagaacttgc tctagatata
    30781 ctgaaatttg tgataaagat ttctatttta tcgttgcagc agcagatgaa aatgtggctg
    30841 atatggaaag aacaatagaa ggatttagag gatttacatc atgtctaaat ggttctaaag
    30901 aaaaaggtat agtatatggt gtaggtgctt ggaatgtagg tgatattaag ggaagtaagg
    30961 caatgaaaca ggcatatgaa atgggtaagt tggcgtagta tgtttgtata aaattgtata
    31021 aaatcgaata tattcttatc atttcaacaa taaaaagagg cttatctata ttttgagaca
    31081 gcctctttgt gctatatcat ttatttttat tctatatcct tattataccc tttatttttt
    31141 tatgcctatt taagtatctg ttgttactca tatattttaa taattaccct taaaaaacta
    31201 tacagattcc tgcataatat tattttcttt agtaattaat ttttctaggt ttttccaatc
    31261 catttcttcc atatttgcaa aataatgacc acttcctatg caagtcagat aagactttcc
    31321 atctaaatca aacgaagaac ctccaataca ctttgaatta catttcttac aagtacgagt
    31381 tttagttata ctatctttaa tagttttaga gcattcctcc acagcatctt tatatgtatt
    31441 tagatgaaaa agatttgctt taactctcca ttttttttca ttacattcaa tagtaaataa
    31501 gctacgtttt ggtttcttag ttgaatatac tattttgtaa gaacgagcac ctgtttttgg
    31561 ttcaatttta caatctaatg atttaccaag ttcatgtaaa tgacatgcaa tatcataatc
    31621 tttaccactt agtacttcta acatttcttc tgttgtttct gccgttaatt cacttttgct
    31681 catattaaaa aaatccccct atataagtaa taatttcaca tgaaaataat taatataagt
    31741 atattaaata aaactattaa aatcaataaa attactacaa tcttacatta ttgggcatag
    31801 aatgagagct aatgatttat tagaaataag acttaatagt atgaaaattt acttagacgt
    31861 ggtacaattc tataaaagat ttaaaactag gaaaggagaa agttgttgag atacggccaa
    31921 tataacaatt tatttataag ttgtaaattt attatgagat taattagatt gttaagtaat
    31981 actatcaaaa ggtagttttt tggattttca gcaacagtgg tagatattga taattttttg
    32041 gttattatta tatttagctg ttatattttc aataggctct atgataacta gggtaaataa
    32101 ggtatgggta aaggttttat tatttataat agtgggattg tcaactatag ttctttcata
    32161 tgtaataact tgataattta agattgaaaa ataactttaa tctgtaaatt ctcaaaacaa
    32221 gaattctcat gttggtaaat ttctagatat gagaaaaaaa ttgacatcat aaaaaagtaa
    32281 ttttaaagca ttgttttacg aaaaaattca gaagtaacta ttttgaatga cttcacaaaa
    32341 ttttatatat aaataaagtt tggcacgtta attgctttaa taaaagttaa caagacacaa
    32401 ataaacataa tcatctaagt attgattatt tgaagtttta gatttgaaat ttaatctaaa
    32461 ggttcgtatt aatattggtg tttaggaaat tttattttcc tgtaaatata acttaataat
    32521 aggaggtgaa gtcatgtcaa aagtagtaat agctacagag aaagctccag gagcaattgg
    32581 accatattct caagcaattc aagttggaaa catagtttct acatcaggtc aacttccaat
    32641 agatatgaag actggcgagt tagtatctga cccaaaagaa gcaacaaaag cttctttaga
    32701 taatgtaaaa gcaatattag aacaagctgg tacaagtatg gataaaatat ttaagactac
    32761 agtattcgta aaagatttaa aggattttaa tgatattaat gaagtatatg ctacatattt
    32821 taaagaaaat ccaccagcaa ggtcatgcgt acaagttgct caattaccaa aagatgcagt
    32881 tttagaaatt gaagcaatgg cagtattata agtattataa caataaaacc aataacaaaa
    32941 ctaataaaaa ttaaaaacta ataaaaaaag tctacaatta aaaaagttta tattaaaaaa
    33001 gtctatataa aaatctatct aaatatttaa ctattgagct tttctcatat aatgtatatt
    33061 tttatgtcaa aaatatattt gttatatgag gaaagctttt ttttattatt gtattgtgat
    33121 ttattttatt gtctgcatat tataattaag gttactatat aaaacaaact ttttataaat
    33181 taatattgtc tgttttaacg caaatatata aataagtaat gttttatata tattttaaag
    33241 agtgactata tgttaaaata tagctaaact gataatttgg taaattaaat tctaatgggg
    33301 gaaactatgt taagtaaatt aaaagaattt caacaagaaa tgataaaata cactgaaaca
    33361 gtagctagtg tgttagatgt agatattgaa atagttgacg atagattaat aagaattagt
    33421 ggcacaggtc tatataaatc aaagataaat gaaagcgttg ttactgaggg ctttatttac
    33481 gacaatgtta tacagacagg tcaggaatta gtcgtattgg atatatgtga taatcagctt
    33541 tgtatagaat gttcccatta catgaaatgc ctaaataaag taataatagc agttccaata
    33601 aaatataata atcgaactat aggagtaatt ggtgctatta gtacagataa aactaaaaaa
    33661 gtagaaataa gtgcaaaaat agataattat ttaaaatttg tcaatcatat atgcgattta
    33721 atttctatga agatagaaga acatgaagcg tcaaaaaata gcagtagaaa aatggatatg
    33781 atgatagaaa tcattgaaaa tgttgaaaaa ggcgttataa tactagacat aaatagcaaa
    33841 atatcttata taaacaatat agctctaaaa aaattagata tagataaaaa tataatagaa
    33901 aatatagtaa atatagtatc tgttgaatct tcctcaaatg gacatgaatt actagaaatt
    33961 gatattgata acaaaattta taatataaat gccaaaataa ttccggtata tccatatata
    34021 aatcaatacg acaaaataat aatatttgac aagacatata tcaatcataa aggacatgga
    34081 aaagtgaata gtggttgggg aaatagtgat atagagtcta taattggaaa ttcagaagca
    34141 atgttaaaag taaaagagag aactaagaaa ttagcaaagt caaattcaac tgtacttata
    34201 actggggaaa gtggtacggg taaagagcta attgctaggg ctatacatgc tgaaggtagc
    34261 agatggaaca agccatttat tgcgataaac tgtgctgcta ttccagaaaa cctccttgaa
    34321 agtgagctat ttggctatat aaaaggtgca tttagtggag ctagtagtgg aggtaaagta
    34381 ggtaaatttg aacttgcaaa tgaaggtgtt atatttcttg atgaaatagg agatttgtca
    34441 atgcctttac aagcaaagtt acttagagtt ttacaagaga gaaaatttgc gagaattggg
    34501 tcaaataaac ttatagattt agatataaga gtgattgctg ctacaaataa aaacttattg
    34561 aaattagtaa atgaaggtaa gtttagggat gatttatact atagattaaa tgtaattcct
    34621 ataaatttgc cacctcttag ggaaagaaag gatgatattg aggcaataat gatgaagttt
    34681 gcttctaaat attctttaga attaggtatt cagttaaata aaatagaaga aaatgtaatg
    34741 aatatgttga ttaactataa ttggccggga aatataaggg aactggaaaa tgcagttgaa
    34801 tatatgatga atttggttgg agatgatgga ataatatata aagatatgct tccattggat
    34861 attttaaatt attataatat taatggaaat atttgtaaaa ataaggatat aaatataata
    34921 tttgaagatg acatagttgg agggatagta gagaatcagg aaaggatact ttcaattaaa
    34981 gaattagagt tgacttacat aaacaagttg ttgaataagt atggaagaga tacaaagacg
    35041 aagaagaaga tagcaaaaga cttaggcata ggtttggcta cactatatag aaaattggaa
    35101 gaggaacagt agtaatataa tattaaaatg ataggtattt gtgtgttttt atagataggt
    35161 atttttactt tatggtggag gtgttattat gcaatatgcg atagagctgt attatgataa
    35221 aaaaacggaa aagcaacttt ttgatttatc taaaaaaatc gctgatgaaa aaattagtac
    35281 gaagtactta gaatggaaaa caagacctca tcttactttg gcttgtttca atgatgtgga
    35341 tgaggcttgt tgcatagaca agctaaaggg gtttgcacaa aaccataagg taatacctgc
    35401 ttacattggt tcagtaggca tgtttaatga tactaaaacg gtgtttgtat cacctagaat
    35461 gaatagcagt atgtatcagt ttcagagaga attatatgag gtactacaag attttgattc
    35521 aaatggttgg gaatggtacc accccaatcg ttgggtaccc cattgcacaa tagcacttac
    35581 tggagatgat gaaagtgagg ctttttttcg ggcaagtgat gtattactgc gtgagttcaa
    35641 aaaaataagt ggtgagtttg tctcaatagg attggttaaa attacatttc ctgtggaaga
    35701 aatttttaca gtgaatatga ataggtaact ttaactctgt tgtggatgtt atgaatattt
    35761 tgcatagtgc atttcatcag ataaatgcga agttgcgaat ttcgacagct caatagtcgc
    35821 aagtagggca caatggtaca catattgcac ttttgcttat tggggggacg cccatgtaaa
    35881 cttctgtaag aagctatgaa aagatttaag ccattttgga ggctttgggt aataaagaat
    35941 atttgggtaa taaagaatat ttgggtaata aagaatataa agtatataaa tttatagagt
    36001 ttatgcgtaa gaaggttata gccatatatt tatagaaaat aaaagtagta atatatctga
    36061 caaaacaata gacatataaa aaataagagc ataataaagg aagaattaag ataaataaac
    36121 gatttctcga attgataatt ctcgtattga taaaaatttc ccaatatgag aattttttct
    36181 tttataaatc ttatttttca cactcaaaat ttataaactt taaagaaatt ttataaaagt
    36241 atgtaattcc aacataaaaa aattgttttt agaataaata atattggcac ggtaattgct
    36301 ttgctataag gcacaaagat aaaaaattaa aatgacaccg aaaaatttga aaggggaata
    36361 taaaataaat gagagaaata aaatggaaat taaataactt acctaaatca gaggaaaaag
    36421 aaaaaggaat tgagttttta agagatgaag aaattgcaaa ggctaaagct tttcatgaga
    36481 gctttccaca atatgaaaag actcctttag ttaaattaga taacttagca aaatcactag
    36541 gcgtaagcgg aatatatgtt aaagacgaat cttatagatt tggtttaaac gcatttaaag
    36601 ttttaggagg ttcttactct atgggtagat acttagctca aagattagat acagatatat
    36661 ctgagttagg gtatgacaaa ttaacttcaa aagaaataaa agacaaatta ggagaaataa
    36721 ctttctttac agccacagat ggaaatcatg gtagaggagt tgcttggaca gctaataaat
    36781 taggtcaaaa atctgttgta ttaatgccaa aaggttcttc tgaatttaga ttaaataaaa
    36841 tcaaaggaga aggtgcagat gctagtataa cagacttaaa ctatgatgat gcagtaagat
    36901 tagctaatga ttatgcagaa gctgatgacc atggagtaat ggttcaagat acagcatggg
    36961 acggatatga agaaatacca gcatggataa tgcaaggata tggaactatg gctaaagaag
    37021 ctatagaaca attaaaagaa tatggagtag atagaccaac acacgtattt gttcaagcag
    37081 gagttggttc acttgctggt gcagttcaag ggtatgttgc ttcaatatat gatgaatgcc
    37141 caataacagt agtagtagag gctgatgagg ctgattgtta ctataaatca gcagaagctg
    37201 gagatggaaa accaagattt gttggaggag atatgccaac tataatggca gggcttgctt
    37261 gtggagaacc aaacactata ggttttgaag tgttaaaaaa ttattcatca gcattcgttt
    37321 cagcaccaga ctgggtatct gctaaaggta tgagaatatt aggaaaccct ctaagaggag
    37381 atgagaaagt aatctctgga gaatctggag cagttacaac tggagcatta gtttcaatcc
    37441 ttgaaagtga agatttaaaa gacttaagag aagctttgaa actagatgag aactctaaag
    37501 tattattaat aagtacagaa ggagatactg accctgataa atatagagat atagtttgga
    37561 atggtgaatg ccaaagtaaa taaaagactt aaggaaaata aaaacttaac aaataaatga
    37621 aaaatttaag gaaaataaaa acttaaataa gtgaaaactt taaataaaat aaaaactaaa
    37681 acaaattaaa aatctaaata aatgaaaaag taaagcaaat aaaaaagtaa agcaaatgaa
    37741 aaattcaaaa taaaaactaa ataaaattaa ataaaaccaa ataaaattaa aataaagtct
    37801 aaataaaaat ttaataaata aaatataaag aaataaaaaa tcaatagatt aagtgaaatg
    37861 ctaataaatt aaaaaagtga aatatcaaaa taaaacgtca acaaattaaa aattatatgg
    37921 gggaatatca aaatgttaaa tgaaacaaga aaaaaacaat taactgaagt atgccaagac
    37981 ttaataagaa atgctagtta ttcaggtcaa gaagaaaacg tagtaaaagc tatagaagaa
    38041 aattttgctt tactaggttt tgatagttgg tcaagagata gatatggaaa tatagtagga
    38101 tgtataaaag gaaataaacc aggtaaaaaa atattatttg acgggcatat agatacagtt
    38161 ccagttccag atgcaagtaa atggagtgtt cctccttttg aagcgagaat agtagatggg
    38221 aaaatatatg gtagaggaac ttctgatatg aaggggcaag taagtgctat gatggctgct
    38281 gtttcatact ttgcagaaga tactaacaaa gactttgaag gtgaattgta tgtagcaggt
    38341 gttgttcatg aagaaatatt tgaaggtgtt tcagctagag agataagtaa ggctgttcaa
    38401 cctgattatg ttgtaatagg tgaatcttca gaattaaact taaagatagg tcaaagaggt
    38461 agaggagaaa tagtagtaga aacttttggt aaaccagctc actctgctaa tccagaaaaa
    38521 ggtataaatg cagtttataa aatggctaat gtaatccaaa agatacaaca attagtacct
    38581 ccaactcatc cagttttagg tgatggaata ttagttttaa cagatataaa atcttctcca
    38641 tatccaggag catcagtagt gccagattat tgcaaagcta cttttgatag aagattatta
    38701 gttggagaaa caagagaagg cgtattagct ccaatacaag ctttattaga tgaaatgatg
    38761 aaagaagacc cagaattaaa tgcaaaagtt tcttatgcag ttgaaaaagc tgattgctat
    38821 acaggaaata ctatagaaag tgaaagattc ttcccaggtt ggttatatga tgaagaagat
    38881 gaatttgttc aagcagcgta taagggatta aaagaagctg gaatagattc agaaataact
    38941 caatactcat tctgtacgaa tggaagtcac tacgcaggtg aggctggaat aagaactata
    39001 ggatttggtc cttctaagga aaatcttgct catacaatag atgagtatat agaattagac
    39061 caattattca aaggtgcaga aggatattat ggtatattaa aatcagttta taaaaaataa
    39121 ttaggagatg gttttgtgag aactttaata aaacatgggc ttatagtaga tggaaataaa
    39181 acaccagcat atgaaggaga tattttaata gaaaacgaga aaatattaaa aatatcacaa
    39241 gatttaaacg aagaagctga caaagttata gatgcaaaag gtagagttat atgtccaggt
    39301 ttcatagata ctcatagcca ttcagaccta gttattttag ttaatccata taatgaggta
    39361 aagattagac agggaattac aacagaagtg ttgggccaag atggtatatc tatggcccct
    39421 ctacctcaag agcatatatc ttcttggaga aaaaatttag caggtctaga tggtgaaagt
    39481 gatgaaattg attggaaata tgaaacaaca gagaattatt taaaaatgat ggattacaat
    39541 ggggtaggtt taaatgaaac ttatttagta cctcatggaa acgttagaat ggaagctatg
    39601 ggacttgaag atagacctgc tactaaagaa gaaattcaaa aaatgtgtga aatcacagag
    39661 agagaattaa aagcaggagc tataggattg tctactggac ttatatatat accttgtgca
    39721 tactcattga ctgaagaaat tatagagatg tgtaaggtag tagcaaaata tgacggagta
    39781 tttgtagttc accaaagaag tgaagcagat acaattttaa cttcaatgga agaaatcata
    39841 gaaattggaa aacaatcagg agtaaaagtt catttttcac attttaaggt ttgtggtaaa
    39901 gcaaactgga agtatatacc acaagttata gagcttttag aaaaagcaga aaaggaagga
    39961 ataagagtat cttttgacca atatccatat gcagcaggaa gtacaatgct tggagtagtt
    40021 ttacctcctt gggcacattc tggaggaact gataagttaa tagaaagatt aagtgatgaa
    40081 aacgaaagag caaaaatgaa aaaagatata gcaaatggaa tagaaggctg ggataatttt
    40141 atagaatttg ctggaataga ccaaatattt gtaacaagcg taaaaacaga aaagaataaa
    40201 gatacaattg gtaagagctt attagaaatt ggaaaaatga gaggaaaaga cccattagat
    40261 gcaacgtttg atttattaaa agaagaagaa aatgcagttg ggatggtaga tttctatgga
    40321 ttagaagaac atataatagg attcatgaaa agagacgagc aaaatgtgtg tacagatggt
    40381 cttttagcag gtaaaccaca tccaagagct tatggttctt tccctaaaat actaggaaga
    40441 tatgttagag agttgaatgt gttaacaatc gaagaagctg tttataaaat gactaaaaag
    40501 gcagctacaa gctttagtat aaaagataga ggcgaattaa aagaaggata ttttgcagat
    40561 atagttatat ttgacaagga tacagttagt ggttgtgatg attttatcaa ctctatgcag
    40621 taccctacag gtatagatta cgtaattata aatggaaatt gtgttgttga agaaggaaaa
    40681 tacaataaaa ttaaagcagg aaaagtactt aaaaattaaa tcttagcttt aaggaggaat
    40741 aaatttatga ttttagtggg gaatgggagg ctaataagcc aagattcttt aaatccctat
    40801 atggaagatg gatgtgtagt aataaatgat aatctaattg aagatatagg tactacagaa
    40861 gaaatgaaag ctaaatatcc agtacatgaa tttatagatg caggcaagaa aataatcatg
    40921 ccgggtctaa taaattcaca tatgcatata tacagctcat ttgctagagg aatggcagtt
    40981 ccaggaaaac cttctgagaa ctttttagag atactaaaca atttatggtg gagacttgac
    41041 aaacagctta cactggaaga tacaaaatac agtgcatatg caacgtatat agaatgtata
    41101 aaaaatggtg taacaacagt ttatgaccat catgcaagtc caaatgcaat tgaaggcagt
    41161 ttgtttacaa tatcagatgt tgcaaaggat ttgggaatta gaacgtgtct ttgttatgaa
    41221 gtgtctgata gagatggtgg aaatacaatc caacaaggta tcaatgaaaa cgtaaacttt
    41281 ataaaatacg ctcaaaaaga tgatacagac atgataaaag gaatgtttgg gcttcatgct
    41341 gcatttacac tatctgatga tacattaaat aaatgtgctt cagagatggc tggtcttgat
    41401 acaggttacc atgtacatgt tgctgaagga ctagcagact tacaatataa tgtagataaa
    41461 tatggaaaaa gggttttaga aagattcaat gattttggag tactaaaaga aaaaacaata
    41521 gcagttcatt gtatatatat aagtgcagaa gaaatcagtc ttttaaataa aacaaataca
    41581 tttgtagttc ataatccaga atctaatatg ggaaatgcag ttggatgttc tcctgcaata
    41641 gagttattaa aaaggggagt tacagtagga ttaggaactg atggatatac tagcgatatg
    41701 tttgaatcat taaaagttgc caatataatt cacaaacatc acttaaaaga cccaagagtt
    41761 ggatttgaag aatcacaaac aatgttattt gataacaata gaaaaatagc taaagcttat
    41821 tataaaaatg acctaggagt acttaaaaaa ggtgcttatg cagatgttat agtagttgat
    41881 tatataccac atactccatt gacagaaaat acaatagggg gacacactat ttttggaatg
    41941 agtggaagaa gcgtagatac aactattata aatggaaaag tacttatgaa agatagaaag
    42001 ttaataaaca tagatgaaga aagtattcta gcaaaaagta gagaattaag tcaaaatcta
    42061 tggaatagaa tttaaataat tgattatgca aaattctatg aagcaggaac cctgtgactt
    42121 tagtcatggg aggttcagat taatatacaa gtaagaaaca agaatttaga tgttaaaaac
    42181 agagcttaaa caaaaatagg aatttaaatg aagtatataa ataaaaaata tacggaatag
    42241 aatattaaat taaatataga agggagaccc aaaatgtctc aagataaaag ccctaaaata
    42301 gctccagtag atgaaaggtt acctgtatcc aaatcttggg tattttcact acagcacgtt
    42361 ttagcaatgt gtgcaggagc agtagcagtt cctatgatga taggaagtgc tgcacgacta
    42421 gatcatgcta gtattgtttt tttaataaat gcttgcttgt ttatggcagg tataggaaca
    42481 ctcatacaaa gtgttggtat aggaaatatt gtaggtgcta aaataccagt aatagaagga
    42541 actagttttg ccgctgtggc aggtatgaca gcaatagcct catcatatag tgattcacaa
    42601 gttgcaatac agacagtatt tggctctgta atagtagctg gattgttttg tatattactt
    42661 gctccagtat ttgaaaaatt aataagattt ttccctagtg tagttactgg aacagttgtt
    42721 atggtaatag gtatttcact atttccagtt gggataaaat ggataactga caacaaattg
    42781 gaagcggttg aaccaaactc attagcatta gctttagcag tattggcaat aactttactt
    42841 tcatttaaat tcttaaaagg aatttggaat agcacagcta tattggtagg tatagtactt
    42901 ggtacactac tttctatggc agttggaatg gcagatttta gtgcagtaaa tggagttggt
    42961 tggcttaact taaatgtacc tttaaaattt ggaatgccta gatttgaacc atctgcaata
    43021 ctatcattgt gtttgattat gttggtactt atgacggaat cagttggtaa tatgatagct
    43081 attcatgaaa tggtagacaa agaagtaaca ggtaaaaata ttaaaagagg tctatttgga
    43141 gatggaatat ctacagcatt atctggaata ttcaattcat ttccaataac tccatttggt
    43201 caaaatacag gaatagtagg tcttacaggt ataaaatcaa gatttatagc agtttacgca
    43261 ggggttatat tgctagtact tggattctta ccaaaatttg cagcaataat aggagcaata
    43321 cctaagcctg ttctcggagg cgtaggattt gcaatgtttg gaatggtaat ggttggagga
    43381 gtaaaaactt taagcaaagt gaaatttgat ggaactaaaa atggggttat agtagcagtt
    43441 agtgttggtt tgtctatgat accactaaca aatcccgatt tctatcataa tttcccaact
    43501 tgggtacaaa caatattcca tagtggaata acaacaggta gtttatcagc agtgcttttg
    43561 aacatattct tcaatgaact aggttctaaa aaagaaaaaa ataataaagt tgaagaagca
    43621 aaataaaaat aaaacaagta aaaatctata ttgacttaaa gtcattaagc attaataaaa
    43681 ataattcaga gatattaata attcaacaaa actatcttat attttaaata atataaaaaa
    43741 gtaaataaat aacgaataca aataaaagaa tacaatctaa atattaaaaa tatttaattt
    43801 aagggagaga taataatatg gctaatttaa aagttaattt atatggaatg gaatttttaa
    43861 acccaattat gacagcggca ggacctggag caaaagatgg tgctctctgt caagaggcag
    43921 caaaaggtgg agcaggagct atatgtacaa aaactatatc tgtattacca gctgatgtac
    43981 caagaccatg tatggcaaaa actaatagtg gttttttaaa cacagaatta tggtcagagc
    44041 ttccaaaaga gcaatggata gaggaagaat acaaaaaggt aaaagaaaca gggcttccag
    44101 taatagtaag tatgggatat tcagcagagc aaatagctga ggttgctcct ttagtaaagc
    44161 cttatgcaga tgcagttgaa ttatctactc attatgtagg tacagacgtt gcaccaatag
    44221 taaatgcttt aaaagctgca aaagctgttt tagatgtacc agtatttatg aaaatgagtc
    44281 ctcatactga cattcaaact attgcaaaag ctgttgaaga agcaggtgca gatggacttg
    44341 taatgataaa ctcatttgga ccatgtatgg caatagatgt aaatacagga taccctataa
    44401 tgggaagtaa agctggatac ggatggttat caggtgcacc aataagacct ctagcaataa
    44461 gatgtatata tgaagcttct caagttgtaa atataccaat aatcggtgtt ggtggaatca
    44521 cttgtggaaa agacgtggct gaaatgatga tggctggagc aagtgctgtt caagtatgta
    44581 cagaagcaat ccttaaaggg ccttctatct atggaaaaat tgctaaagaa ttaaatgaat
    44641 ttttagatga gaatggatat gctgatgtta atgaaataaa aggattaact cataagaaaa
    44701 tggcagctag agggtttaga actcattcag tagctccagt agtggatgat aacaagtgca
    44761 tcaaatgtaa gcaatgtgta acaagctgtg tatacgaagc tttagaagtt acagataagt
    44821 tgaacataga tgcagacaag tgttttggat gtggattatg tgtaactaga tgtccaaaag
    44881 gagctttaag catctgctac aatcaagtag aagctatgaa tgagtaataa ttatatagaa
    44941 ttttggtaat taacttagag taataggtat taggataata aaatatatca gataaacaaa
    45001 cacacattat gcattaataa tacagtctaa agttaataat tttattatat tgatttaact
    45061 aaatattagt ttagctgaat attaatttaa ttaggtattg gtttaatctt aatatagatt
    45121 tactacgtat aagtgaacta actagattac tttaagttaa ttttttcata taaaataaat
    45181 tgatacatta caagtaaggt ggagtctata tgggaattgt tttaaaaggt gggaaagtag
    45241 taacaagtga aaaaacttac tgtgcagatg taagaataga agatgaaaaa atagtcgata
    45301 taggtcttga tatatcaaaa gaaaatgatg aaatggttga tgttagtgat tcttatgtta
    45361 taccaggagg tatagataca cacacacact ttgacttaga tacaggcgtt actaagacag
    45421 cagatagctt tgagacagga acaaaagctg ctatagtagg aggaactact actatattgg
    45481 attttgctac acaagctaaa ggatgttctt tgaaagacgg attagaagaa tggcatgaaa
    45541 aagctaagga taaatcctat tcagattatg gctttcatat ggctataaca gattggaatg
    45601 actcggtttg taatgaaatg gaggatatgg tgaaagaggg agtatcttca tttaaactgt
    45661 atatggcgta taaaggaagc cttcaagttg atgatggtgt aatctttgaa gcattgagaa
    45721 aagcagaaga gataggaggg attattggtt tccactgtga aaatggggac ataatatgtg
    45781 aacttgtgga taaagcaaag tcagaaaata atttatctcc aaaatatcat caattaacta
    45841 gaccagctat aatggaggca gaagctacat caagacttat gaagatagct gaagttgcaa
    45901 actctaaagt atatgtagtt cacttaagct gtaaagaatc cttagaggag gttttaaaag
    45961 ctaagcaaag aggtgtggat gtaatagttg aaacttgtcc tcaatacctt ctattaaatg
    46021 atgaattata tgatttagat ggatttgaaa gtgctaagta tgtaatgtca ccacctttaa
    46081 gaaataaaga aaataatgaa atattatgga atgctatttt agataatcaa atagacacta
    46141 taggaacaga ccattgttct tttaattata agggacagaa ggaacttggg ataaacgatt
    46201 ttagtaagat accaaatggt tctccaggtg tagaacatag gatgagtctt ttatacacat
    46261 atggagtctg taaaaataaa atatctatca acaagatggt agaagtaaca tcaactaatg
    46321 cagcaaagtt gtttggaatg tatcctaata aaggaactat agaaataggc agtgatgcag
    46381 atatattagt cttaaatcca aacaaaaaat ccaaaataga agcaaaaaaa caattacaaa
    46441 atgtagatta tacaccttat gaagggtatg aagtggattg tcaaatagaa catgtttatt
    46501 taagaggaaa agaagtagtt agagatggag aattaatttg taatactcca agtgggagat
    46561 atataaatag gcgtctaaca aagggggcta gagaatggta gaatttatat taaatggaga
    46621 gaaagttgtt gcaaaagaag gcaaaaaact tttagacttc cttagagaag atatgaatat
    46681 aacttcagtt aaaaatggct gttcagaagg tgcttgtgga acatgtatgg ttataataga
    46741 tggtaaagct actaaagcat gtgtatttaa aactgataaa ttagctggga aaaacataac
    46801 aactatagag ggattatcag agagagaaag agatgttttt gcatattctt ttgctagtca
    46861 aggagctgta caatgtggat tttgtattcc aggtatggta attagttcaa aagcacttat
    46921 agatgttaat aataatccta ctgaagatga tataaagaaa gctttaaaag gtaatatatg
    46981 tagatgtaca gggtatgtaa aaataattaa agctgtcgat ttagcagcaa agatttttag
    47041 agaaaatata gatgtgccaa aagtaaactg taagggtcta gtaggtgaaa atcttcctag
    47101 agttgatgca gttggcaaag cacttggata ttctgaatat gtagatgata tgagaattga
    47161 gggtatgatt tatggttcag cagttagagc taagtatcct agagctttag ttaaaaaaat
    47221 agatatagaa gaagcaaaag cttatccagg agttgttgca gttctaacag ctaaagatat
    47281 tccaggaact ataaaggtag gacacttaaa gaaggattgg gatactttaa taccagaagg
    47341 tgaaataact agatacttag gagatggaat agttttagta gcagcagaaa ctagagaagc
    47401 gttagaagag gccaaaaagc tagttaagat agattatgag gaattaacac cattaagtac
    47461 tacagcagat gcacttagag aagatgctcc aaagatacat gagacaggga atatacttgt
    47521 taaggaacat ttagtaagag gaaacgctaa agaaaagata gaaaattcaa aatatgttgt
    47581 aactaaaaga tatactacac ctgctacaga acacgcattt ttagagcctg aatgtgcagt
    47641 agctggtcct tatgaagagg atggagtaat aatctattca acagaccaag gggtgtttgc
    47701 cactcaacat gaatgtgcag atatgttagg gttaccatat gagaaggtaa gagttataaa
    47761 caaaatggta ggaggagggt ttggtggaaa agaagacatg agtgttcaac accatgcagc
    47821 cttacttgca taccatacaa agagatttgt aaaagtacag ttaacaagaa aagaaagtat
    47881 tattgttcat ccaaaacgac atgccacaga aatggaattt acgacagcat gtgatgaaaa
    47941 tggatactta acgggtatga aggcaacgat aatatctgac acaggtgcat atgcctctct
    48001 tggaggacca gtgctacaaa gactgtgtac tcatgcagca ggaccataca attatcaaga
    48061 tattgatata acaggaacag cagtatatac taataaccct cctggaggag catttagagg
    48121 atttggagtt acacagagtt gttttgcaac tgaatgtaat ctaaatttac ttgctgaaat
    48181 ggttggaata tctccttggg agataagata taaaaatgca ataagacctg ggcaagtttt
    48241 accaaatggt caatttgcag atgaaggaac agcaatggca gagacactag aagctgtaaa
    48301 agaagagtat gaaaagcatc cacgtgcagg tatagcttgt gctatgaaaa atagtggggt
    48361 tggagttggt atacctgatg ttggaagatg tagattagtg ataaaagatg gcaaagttca
    48421 cataagaaca agtgcttctt gtataggtca agggcttggt actgttatga ctcaagtagt
    48481 ttgtgaaact gctagcctac ttcctgaaaa tatagtgcat gaagttccag atactcattt
    48541 aacaccagac tctggtaata ctacggcttc aagacagaca gtatttacgg gagaagctac
    48601 taaggttgca tcaaataagt taaaagaagt tttagactct ggcaaaactt tacttgattt
    48661 agagggagaa gagttttatg gagaatatga aagtattaca gataaaatgg gttgtgacaa
    48721 agaaaatcca gtaagtcatg ttgcttatgg atatgcaaca caagttgtaa ttctggatga
    48781 aaatggaaaa ctagaaaaag tagtagcagc acatgatgtt ggaagagcta taaatccaat
    48841 cagtttagaa ggtcaaatag aaggtggagt agttatgggt cttggatatg ctctaaccga
    48901 agattaccca gtagttaact ctgttcctac agctaagttt ggtacattag gtttatttaa
    48961 atctacagat ataccagaaa tacaagcttt aatagttgaa aagaacaaag atttattggc
    49021 ttatggggca aaaggggtag gagaaatttg tacagttcct actgcaccag cagtacaaaa
    49081 tgcctattat gtatttgata aagaatttag aactgagcta ccactacaaa atactccata
    49141 tagtaaaaaa aagtaacaaa aaaaagaaat attaaataaa aaaatagatg aaattgtaaa
    49201 taaaaaaaac ccttttgcat aaggtatatt ttaaatgata gaatatacat atacaggagg
    49261 gtttttcttt tataaaataa gtttaataaa attgagaggt gagcagaatg aattttaata
    49321 atagtctaga attaactcag tctcagaagc taataatgac tacacaactt aagcaatcat
    49381 tatcaatatt aaatatgagt aagttagagt tagaagaaga gataaaaaga gaagcagaga
    49441 ataacccatt agttgaagtc gagaaaagtg gggagataaa ttgggaagag tatataaaag
    49501 acatggatag gtcaagacgt ttagatagaa cagagataag ctataatcct gataatgaag
    49561 ttaatctaga aaatttagtt aaatattcgt caaatttata tgaagattta aaatttcaga
    49621 taagcctgta taaacttaca gacaaagaat tggaagtctg tgagtatata attgatagtt
    49681 tagatgagga tggatattta agaactgagg aaaaagtaat tgttgatacc ttaaagatag
    49741 atgaagaact ttttgaaaaa tgtttaatta gtgttcagca gttggaacct agtggagtag
    49801 gggcaagaag tctttcagaa tgtctgatga tacaaatggc tagtttagga atatataatg
    49861 aaattttaga ggaaatcgtt acaaaagact taaatttaat tgcaaataat aaatacaaag
    49921 agataagtaa aaagtacaat atgtcattac aaaaatgtgt tgaactaata aacataatta
    49981 agacattaga ccccaaacca ggaagaactt gttcagtaga gaaaagtgta tacattcaac
    50041 ctgatgtaac agtagaaaaa attgatgatg aatttattgt atatttaaat gaaaaagatt
    50101 cttatcaaat aagaatcaat agttattata aagacatatt aaaaaattca cagtctgatg
    50161 aaagtgcaaa agaatttata aaagaaagac taaattcagc aacaggactt atgaaaaata
    50221 tagagagtag gaaaactaca gtacttaaga ttgcagaaga gatagtaaaa gctcaagatg
    50281 aatttttgag aaaagggaca aaatatataa aacctttgaa aatgaaagac atagcagaaa
    50341 aattagaatt tcatgaatct actataagta gaggtgtaaa tggtaaatat atgctaacac
    50401 cttttggcgt atatgaattt aggtactttt tcagtagcgc cattgagact gagaataatg
    50461 aaatggcatc tagtacaagc ataaaaaaaa ttataaagga aacaataaaa gacgaaaata
    50521 aaaagaaacc tttaagtgat gaccatatat ctaagttact aaaagaaaaa ggaatcaatg
    50581 ttgcaagaag aacagttgcc aaatatcgtg aagaattagg aatcccatct tcaagtaaga
    50641 gaaaagaata ctaataagta aaagacaaat atcagtatgg taaggggaaa aggctaatta
    50701 agagatgaat gtagattggg ctaaaaattt tatgaaataa aataatagaa tatggaaaag
    50761 tattaaaatg ctataagata ttaaaaaact ggggaacatt aaaacattaa gatagcaaag
    50821 aacataaaaa actaaagaag attaaaacat taaagaacat tagagctttg aggaatatta
    50881 gaactttaaa gaatattaaa atttataaag tataaaaata ctaaaaagaa ttgaaaaact
    50941 ggggaacatt aaaatattgt aaaatgctaa aaaactagaa aacataatta aataagtgct
    51001 tataaagaat gattaaatta aataagtgtt tgtaaagaat aattagatgt tagaaaaaga
    51061 aggataccta gataaataaa ctattattaa atttaataat cacaaaagga aaacacatag
    51121 ggtataaata aaaattttaa ctagataaaa gtaaacttgt agataaaagt aactagaaat
    51181 aaaattattt atagtaataa atattagaat gaaaatataa aaaaatatat ataaaaagcc
    51241 ttatataaaa agaaaaaata ctgtgatttg aaaatggtgg agaaatattt tataaaataa
    51301 aaaaataaaa aagtttttga aaaactattg aaatctatac gcaaatccta taaaataaaa
    51361 atatcttgtg ggacttaaat aaacactagg gacgaaaaaa gtcccgaaag gaaagcaata
    51421 aggagtatgt tatgaagaac ttattagaaa ttcaaaagaa attgattcca caggcaattg
    51481 aacttatgga aagaagatac tctattttaa gacaaatatc tttaagtgaa ccaataggta
    51541 ggagaacatt atcaaatgta ctagagatta gtgaaagaat aatcaggtca gaaactgagt
    51601 ttttaaaaga acaaggactt atagacgtag ctgtatctgg gatgactatc actaaagaag
    51661 gttctgattt gttagataaa cttaaggaca tcatgagtga catcatggga ttgtctaagt
    51721 tacaagatag agtcagagaa aagcttggaa taaaaagggt aatactagtt cctggaagct
    51781 gtgatgaaaa tggaagttta ctaaaagatg taactagata tggatgcgag tatttcttag
    51841 gtattttaaa agatggagat atcgtttcaa taacaggagg aagcactatg ttggagtttt
    51901 caaacgttat taaaactgat aagagatacc caaactctac aatagttcca gctagaggaa
    51961 gtatgggaac tgatgtagag atgcaatcta acaatatagt tgcttcgata agtaagaaat
    52021 tacattctaa ttgcaaactt ttacatatac cagatgagtt ggatgaaagt gcaatgaaaa
    52081 ctcttagcca agtgccagag attaagacaa ctttggagta tattaaaaga acagacattt
    52141 tagtttttag tataggtaga gcagatgtca tggcaaagag aagaaaactt ccagaagata
    52201 aggttgatga gatattatct aaaaatgcag ttggagaagc atttggatat tatttcaaca
    52261 aagatggaga aatagtttac aaactgaaca ctgttggaat tgatttagaa acagttaaac
    52321 aagtaaaaga aactattgca atctttgcag gtactgaaaa agtagaagcc ttattagcta
    52381 tatcaaatat gcataaaaat atggttcttg taacagatga agaaagtgct tataagatat
    52441 tgtcattatt ataaaagtca agacctagca cagagctaga aaacatacat ttactttata
    52501 ggaggtagcg aaaatggtta aagtagctat aaatggattt ggaagaatag gaagattagc
    52561 attaagaaaa atgatggagc aacaagataa gttcgaagtt gttgcaataa acgacttaac
    52621 agacgctaaa atgttagctc atttatttaa atatgataca gctcaaggaa gatttaacgg
    52681 agaaatagaa gttaaagaag gtgcttttgt agtaaacgga aaagaaataa aagtaacagc
    52741 agaaagaaat cctgctgacc taccatgggc tgaattagga gtagatatag tattagaatg
    52801 tacaggattc tttacatcta aagataaagc tgaagctcat atacaagcag gagctaagaa
    52861 agttgttata tctgcaccag ctactggaga tttaaaaaca atagtattca acacaaacag
    52921 tgacatatta gatggttctg aaacagttat atcaggagct tcttgtacta ctaactgttt
    52981 agctccaatg gctaaagtat taaatgataa atacggtata gaaaaaggat taatgactac
    53041 tatacatgca tacactaatg accaaaatac tttagatggt cctcatccaa aaggtgattt
    53101 aagaagagct agagctgctg ctggaaacat agttccaaac actacaggag ctgcaaaagc
    53161 aataggctta gtaatacctt cattaaaagg aaaattagat ggggcagcac aaagagtacc
    53221 agttgtaact ggttcaataa ctgaattagt ttgtacatta ggaaaaaatg ttacagttga
    53281 agaaataaat gcagctatga aagaagcttc aaacgaatct ttcggatata ctgaagaaat
    53341 gttagtatct tctgacataa tcggaataag ctacggttca ttatttgacg ctactcaaac
    53401 aaaagttatg gaagtagatg gaaaacaatt agttaaagtt gtttcttggt atgataatga
    53461 aatgtcttat acttctcaat taataagaac tttaggatac tttgcacaat tagcaaaata
    53521 gtcagttttg ggaaaataga aaagtagatt gacaaagtcc gagtttgtag tttaatacta
    53581 cggactcagg acttttttta agaaaaaata tataaaatac acctaaataa tgttacatac
    53641 tatatataaa aatatgataa tatgatatat ttaatagggt aaaagtatgt actatattat
    53701 acttggcaat aaaaaattac tttattaaaa ggagagatat ttatgtcaat gcttaacaaa
    53761 aaaactatag aagatattga tgtgtgcgga aaaaaagtat tagtaagatg tgactttaat
    53821 gtgccattac aagatggtgt aattactgat gaaaatagat tgaacggagc tttaccaact
    53881 attcaatatt taatttctaa aggggcaaaa gttatattat gctctcactt aggaaagcca
    53941 aaaggagaag ctaaaccaga attatcttta gcaccagtag caaagagatt atctgagatg
    54001 ttaggaaaag aagttgtatt tgcagcagac gataatgttg taggagaaaa tgcaaagaaa
    54061 gcaactgaaa aaatggaaaa cggagatgta gtattattag aaaatactag atatagaaaa
    54121 gaagaaacta aaaacgaaga gaatttctct aaagaactag catcacttgc tgaaatattt
    54181 gtaaatgatg catttggaac tgctcataga gcacattgct caacagttgg tgcaggcgag
    54241 tttttacaag agagagtttg tggatactta attcaaaaag aattaaaatt cttaggagaa
    54301 gctgttgcaa accctgtaag accatttaca gctatacttg gaggagctaa agtttctgat
    54361 aaattagctg ttataaacga attattagaa aaagttgata atctaataat aggtggagga
    54421 atggcttata cattcttaaa agctcagggt tatgaagtag gaacttcttt acttgaaata
    54481 gataaagttg aatatgctaa agaaatgatg gaaaaagcta agaataaggg tgttaactta
    54541 ttattaccag tagacgttgt tatggcagac cactttgcac cagatgctac tccaatagta
    54601 acagaagatg ctaatgtaaa agaagattac atgggactag atatgggacc taagactata
    54661 gcaaactttg taaaaactat aaaagaatca aaaactgtag tatggaatgg gccaatggga
    54721 gtatttgaat ttgaaaactt tgcaaatggt acattatcag tggctagagc tatggcagag
    54781 ttgactgatg caactactgt aattggcggt ggagatagtg cagcagcagt taatcaatta
    54841 ggatttggtg acaagatgac tcacgtatca acaggtggag gagcatcact agaattttta
    54901 gaaggtaaag aattaccagg tattgcagca ttagataata aataaactaa tatatagagg
    54961 agattgtaaa atgagaaaac ctataattgc aggaaactgg aaaatgcata aaacaataaa
    55021 agaagcttta gaatttgtaa atgaagttaa agataaagta aattctgata aagtagaagc
    55081 tgttatatgt gcaccattta ctttattaaa ggatttaaaa gaagctacta agggtacaaa
    55141 tataaagata ggtgctcaaa atatgcactt tgaagaaaaa ggagcattta caggagaagt
    55201 ttcacctctt atgttaaaag aaatagatat ggactatgtt gtaataggac attcagaaag
    55261 aagacaatac ttcaatgaaa ctgatgaaac tgtaaacaag aaagttttaa aagcattaga
    55321 agtaggaata gacccaatat tatgtgttgg agaaacttta gaacaaagag aagctggaaa
    55381 aactaaagat gtttgtaaag ttcaagttga aaaagcttta gaaaatgttc ttaaagatga
    55441 tttggcaaaa gtagttgttg catatgagcc aatctgggct attggaactg gtaaaactgc
    55501 aactgctgaa gatgctaatg acgttatatc ttatataaga gaagttataa aaggattata
    55561 tggagaatta gctaatgaag ttagaataca atacggtgga agtgttaaac cttcaaatgt
    55621 agccgaaata atgggtcaaa gtgatataga tggagcttta gtaggtggag ctagtttagc
    55681 tagtaatgat tacctagacc ttgttaattt ctaaggagtg aaatgatgaa aaaaccagtt
    55741 gctttaatta ttatggacgg gtttggatac aataaggatg ttaagggaaa tgcaattgct
    55801 gagtccaaaa ctcctaattt agatagaata aaaaaagagt atccaaacac attgataaat
    55861 gctagtggtc ttgatgttgg tttacctgat ggtcaaatgg gaaattcaga agttggacac
    55921 actaacatag gtgcaggtag aatagtatat caagatttaa ctagaataac aaaatctata
    55981 aaagatggtg acttttttac taataaagtt ttatgtgaag caatggataa tgcaaaagaa
    56041 aattctcttc atgtaatggg acttttgtct gatggaggag tacattcaca tatagaccat
    56101 cttaaggcta taatcaaaat ggcaaaagat aaaggcgtac aaaaggtgta tgttcacgca
    56161 tttactgatg gtagagatac tgaccctcaa agtgcattag aatatgccaa agaagtacaa
    56221 gctagtatgg atgaaattgg agtaggtgaa tttgctacag tttctggtag atactacgct
    56281 atggatagag ataagagatg ggaaagagta gaacttgcat acaatgccat ggtcagaggt
    56341 attggtgaaa aagcaaattc tattgaggaa gctattcaaa actcttatga tgatggaaaa
    56401 aatgatgagt ttataatgcc aacagttatt atgaaagatg ataaaccagt tggaagtata
    56461 aaggaaaatg attcaattat attcttcaac tttagaccag atagagctag acaaataact
    56521 agagctttag tttgtgaaga gtttgatgga tttaaaagag aagatattaa aaacttcttt
    56581 gtatgcttaa cagagtacga tataactata gagaatgtgc atatagcatt tggacctcaa
    56641 tctttagcca acactttagg tgagtatcta gctaaaaatg gaaaaactca acttagagct
    56701 gctgaaactg aaaagtatgc acatgtaact ttcttcttca atggtggagt agaagagcca
    56761 aataaaggtg aagaaagact attgatacct tctccaaagg ttgcaactta tgatttaaaa
    56821 ccagaaatgt cagcatatga attgacagat aaagctttag ataaattagg agaagataag
    56881 tttgacttta tagtattaaa ctttgcaaat cctgatatgg taggtcacac aggaagtata
    56941 gaagcggcta taaaggctgt tgaaactgta gatacttgtg taggaaaatt gatagataaa
    57001 atagtagagt taggtggaag tgcaataata actgctgacc acggaaatgc tgaatatatg
    57061 ttagacccgg aaacaggaaa aactgtaacg gctcactcta ttaatccagt accatttatt
    57121 gtagttggtc aagaatatga aagtgcaaaa ttattggatg gaggaagatt atctgatata
    57181 gcaccgactg ttttagatat gatgaagtta gaaaagccag aagaaatgac tggtcattca
    57241 cttatttcaa aatagtcgat tctgataagt agagaataat atataaacta caatataaat
    57301 ttaaaaataa tgcagtttag gtttattttg taaagtttag actttatgac ataagattta
    57361 gattttgtaa gttctggata ttgtaaggtg tagatgaagg tatattttat aaaatttaca
    57421 agatagacaa tttataaaat aaaaaattat aatatagata ataatgtaaa taatg
//
LOCUS       DACTZW010000015        56951 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.015, whole genome shotgun sequence.
ACCESSION   DACTZW010000015 DACTZW010000000
VERSION     DACTZW010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 56951)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56951)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56951
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.015"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            5..388
                     /locus_tag="JAM15_04950"
     CDS             5..388
                     /locus_tag="JAM15_04950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HAT6797610.1"
                     /translation="MGFKKLPDSELKVMKFIWGLDKNKVASGEVVEAMKQIYDWNKNT
                     TLTILSKLAKKNYLYSQKTSKCTYYTIAVREKDYLKVETKKFFSFFHNNSLKSFFTAL
                     NDEEDLSDDKLDMLEQWVKNWEEDE"
     gene            1067..2497
                     /locus_tag="JAM15_04955"
     CDS             1067..2497
                     /locus_tag="JAM15_04955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphatase"
                     /protein_id="HAT6797611.1"
                     /translation="MILNQIFIEDGGIMRNKIIIGITFSLVLLMSGCASKQTAEINVL
                     ATTDLHGVIPYELTSYVKEERKKDKNLTLVDAGDFFDSGEVSGSSMDSYFSARYKDID
                     NNTERYIETPISKDMKEVGYDVAVLGNHEFISNNKFYLDNMISDFEKQKINILSANTY
                     KKNGDSYTKPYIIKNINTPEGNVKLGILGLTIKEVGERKQWKDGKLVDSKSLELKDQE
                     GYNGELYMNDLVEDAKKWVGIMEKEKPDIIVAVAHTGEKPKKPKNPGNRIQDLAQQVD
                     GIDAIVAGHNHVQIEQHDYKNKSGENVIVTEPGKHGECISKINFKLEKNNDKWNIVDK
                     SSKLIKFEKNQESDKFGEFISSINKVSKDKKEIRLSEVKTPEWDKIYVFKSGTSADDI
                     YKTIGYKWRNISSPKGDDMVQIVVMNNNKPVSYVYGEAEVMPINIKCDESEYKDNVVT
                     IYPNKNDKFKIEKGKQEYSINLKHIQ"
     gene            complement(2645..3520)
                     /locus_tag="JAM15_04960"
                     /pseudo
     CDS             complement(2645..3520)
                     /locus_tag="JAM15_04960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904812.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            3640..4203
                     /locus_tag="JAM15_04965"
     CDS             3640..4203
                     /locus_tag="JAM15_04965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HAT6797612.1"
                     /translation="MNQSRKTYFWLLIINLFISTFTFGGGYVVVPMIRRYFVNQKQFF
                     TEDDLMSMAAVAQSTPGAIAINLSALAGYRVAGTLGVVISCIAAIIPPLVILGLVSAF
                     YTTFISNAIVTAVLKGMQAGVAALIVDLIIDMCSMILKQRSLFLSAMIPIAFFANFVM
                     SINVIFILSVCCFVCVMQVFYKKRENK"
     gene            4200..4766
                     /locus_tag="JAM15_04970"
     CDS             4200..4766
                     /locus_tag="JAM15_04970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HAT6797613.1"
                     /translation="MNTIWNLFFIFLKIGLFSIGGGYAIIPLIQEKVVNQTGWISEKM
                     FTDIITISQMTPGPLAVNTSTFVGLQIGGFWGAFAATLGCVLCGVVISLFLYNFFQKH
                     QNSTYIFEILNGLKSASLGLIISAAATIIILALFGTNKVYFNSIFEMLNWTALIIFFV
                     TLLIVRKWKINPIVIIIISGILGIFFYL"
     gene            complement(4895..5131)
                     /locus_tag="JAM15_04975"
     CDS             complement(4895..5131)
                     /locus_tag="JAM15_04975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797614.1"
                     /translation="MLECFIAEDSKIKDGVNIPTLVFKTLHDRYFKTQYFDSYYNSLK
                     CKKKLVEINNVHNSYYIDSEKFCQEAYDCFVENQ"
     gene            complement(5441..8869)
                     /gene="uvrA"
                     /locus_tag="JAM15_04980"
     CDS             complement(5441..8869)
                     /gene="uvrA"
                     /locus_tag="JAM15_04980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HAT6797615.1"
                     /translation="MKINNYKNQSIITNPKKFENKYQDLPKTPIELLKVVQSLVIHGD
                     QGKLYGISFNKQQSDEELLRTVPQMLKRIFEINSNPLTIPRNPKQRLVGMCRDYSLLL
                     VSLLRYRGFEARMRAGFANYFESELTYEDHWLVEYYDTLTKRWIRIDAQIDDIQKNYF
                     QINFDTHDVGKTDGFLTGSEAWIRCRQGHAHPDDFGYNKNWKGWHSVKGNLLHDFNNM
                     IGLELLPWDLWTELSSKKYNQLTRAEKNLLDEMAEILSSGNIKIEDLNLLIEKLPEDY
                     LKSIFSQLKILGISEIKELGNPLELEKKFKFAKAINKSIKNSLCHNKSSIYLKGGRQN
                     NLKDVEVTIPKNQITVITGVSGSGKSSLAFDTIYEEGKRRYFENLGNGAKLSEQLQKP
                     EFDLLQGLTPTIAIEQKKGSQNPRSTVGTLTSIWDYLRMLFVSIGKSYCPYCKIPLEK
                     KNNTKNYCPHCQTIFSKINTSTFNANSHTGACHDCNGLGFTYQVNPQLIVKDPTISIL
                     DGATYYFGKLRGKKPNGNWMVGELYAIAKDKNIDLDIPWNELPRDFIYAILYGTDDKI
                     YEFSFESKGRESKIRRPASGAINHIQRLFRESSSENNTLHQYMNKIPCNTCGGELLCI
                     EARFTTIKGYRFPELTKMTIEQLWNWLCELPNQLQKNELSLVNDILTELKIRVSYLLK
                     VGLSYISTDRAAPTLSGGELQRVRLSSQLGSELVGLTYILDEPSIGLHPRDHNLIIKM
                     IEELRDKGNTVIVVEHDKDTILSADYIIDVGPSAGTKGGFIIAEGTTQEIIKNPNSIT
                     GKYLSTYNKISSQNKIIPSKWLSLKGCHANNLKNIDVEIPLNCMCSITGVSGSGKSSL
                     VFHSLLPALEEKLKQKSIPDKNYTEFTGFDAIDDFILMDQTPIGKSSRSTPATYINIF
                     DEIRSLFAETPQAKQKLLDESYFSFNSKKGQCPNCQGLGKTKIILQYMADQWVTCSEC
                     QGKRYQKEILSIQYKGKTIADILDMEVAEAKTFFSDCSDIYRKLSLLDEVGLGYLKLG
                     QNTLGLSGGESQRIKLAKELGTKTKKRMLYILDEPTTGLHFKDIENLLITFRKLVNEQ
                     HSLLIIEHNTEVIRASDWIIDIGPDSGINGGEIVASGTPDEIKINPNSITGHFI"
     gene            9188..11422
                     /locus_tag="JAM15_04985"
     CDS             9188..11422
                     /locus_tag="JAM15_04985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HAT6797616.1"
                     /translation="MKLSRYKKNSLVLSIILCSLIISILVITVFNTVKLHNISNKQSK
                     NYLNDVSTQIVMNVDSKIKFILSDLRIMADFIKQYEGDSRYEYLSKRKTSYKYYDVGI
                     IDLEGKAEFLSGKKFDLKNTASYKKGIEGKEYSEVIESMGFVLYSVPIFNDNHEVSSI
                     LIGVSNKESMDEILNIDSFNGEGTIEIINSQGKTLFIGKNNELIKDLSYKYKDSADEP
                     WAQKMLNDFKNDKSGNITITSSKGVQCLLTYHPITRGLNDWHFLLIVPEDAVLGELNK
                     LNSFTIIMTFITTCIIGIITLILYIIRRKYVNQIENIAYLDSITNGINSTKFSMLVKP
                     LISESPDSTYMMIAMNIKDFKLINDCFGSEKGNMTLKHLYNILYKNIDENEEFVCRHD
                     ADLFYLLIKNRPVLEALELLYKIEADTNYFNKNRENPYFLRLSVGIYTIENHNEDLIT
                     IQDHANTARKSFNKTHQSDFSFYSDIERKRLISEKEISNLMEKALENKEFFMCLQPKI
                     DIKSGKISGAESLVRWKNSEKGIIYPSNFIPLFEKSGFICKLDLYILEETCKLISKWI
                     KEGKEVLRISVNVSRQHLNDKLFLEKYKHICNKYNVPTCLIDLELTESIFLENPEAID
                     IIEDIHSNGFKCSIDDFGFGYSSLGILKDFKVDIIKLDRSFFVSKNNIDRGKVVIKSI
                     IELSKRLGMKVTAEGIEELEQVEFLKNVGCDYIQGYVFSKPLLISDFENFAYENNKIK
                     NIHY"
     gene            11678..13708
                     /locus_tag="JAM15_04990"
     CDS             11678..13708
                     /locus_tag="JAM15_04990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAT6797617.1"
                     /translation="MISGRMLLIMNFLKGKNKTSYKDISKQLSIEERKVRYDINNLNI
                     VLRSLNKSVIQKMNKGVLIIPDDFQVVCINNNEYVFSLTERVSIMKIISMFKIDNLNL
                     EKLSKEFQVSRSSIKNDLNVLSSELERNQITITYDKSFKISGEEDLIYKQRLNILKSY
                     SYLFGKEKSDLSVFEKYLVNVIEKIFKGIYLIDIYNWSMNLLLQMGWTLNDESFTWYV
                     SNIFLFTWYIHSDEKHPLESASLSEPCFENKFDQEFETIIQKKLTKEQIFLLKSFVFF
                     TNKYASLNEDMDLISTEIIVQDLIYNMSEILEISFKEDMILYKGLLNHIAPLIERIKQ
                     NIQIYEELLHVIPDKYQYVLEATKVSIQKNRVLSQIKNENEIILLAIHFLGSIHRNER
                     NNYKNILLVCGFGYGVIAMLKDSLVNDYQINIVESIPSYKLQDYKEWESIDFIITTSK
                     IVIDLPKTIIEINPFLQEEDYLKFEEKGIKRKNVLTNYMSIKKRLDFLEEDAQKRVLS
                     IICQELGYSDERILFRQLNLSDLIGIDTIRIIDEDMKWEDAVKISSNILANCDFVSAQ
                     YAENIIDILKNVGFYAVKDNEFALLHGNDSSLVKVSSISLLICKEAVSFGDKKVKIIF
                     CLASRDKKEQIPAIINLTKMVYKTNFIAMLESAKTKEEAEVLIHKYEKEVTV"
     gene            13705..14157
                     /locus_tag="JAM15_04995"
     CDS             13705..14157
                     /locus_tag="JAM15_04995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAT6797618.1"
                     /translation="MNKLVNVKCSFKIHANSKEEAIVSLVDVVSKEGYLIDKNQFLED
                     VLKREETLSTYIGHGIGLPHSQSVGVKNSCITIGKLDIPIEWTEEGEKVDLIFLISVT
                     KDNENNLHLKILSKLARLLMHESFRNQIRCSDEQTVYNLIKEKIEEED"
     gene            14159..15214
                     /locus_tag="JAM15_05000"
     CDS             14159..15214
                     /locus_tag="JAM15_05000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit EIIC"
                     /protein_id="HAT6797619.1"
                     /translation="MRILKFLQKHLMTATSYMIPFVVAGGILFALSVTLSGQAAVPET
                     GWLAKLNQIGAAGLALFIPILGGYIAFSMADKPGLAPGMIGAYLAKEVNAGFIGGIIA
                     GFIAGFVVLQLKKIKLAPTMRTLGSIFIYPLIGTLITGGIIVFLIGEPIASFMTWMTN
                     WLNGMSGVSKIPLGGILGGMIASDMGGPINKVAATFAQTQVDTLPYLMGGVGVAICIP
                     PIGLGLATLLFPKKFSKEERDSGKASLLMGCVGITEGAIPFATSDPVRVIPCIMAGSI
                     IGNIMAFLLGCLNHAPWGGLIVLPVVDNRLGYIASVLTGAVVVAVLMKLVKKDVKEDE
                     EIEEDLDESIELIFEEL"
     gene            15281..15589
                     /locus_tag="JAM15_05005"
     CDS             15281..15589
                     /locus_tag="JAM15_05005"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HAT6797620.1"
                     /translation="MKIVAVTSCPSGVAHTYMSAESLELSAKKFGIEIKVETQGSSGI
                     DNELSLKDIDEATCVILTNDVEIRNMERFKGKKVVRMSVSEIIKKSDALIKKIKDTFQ
                     "
     gene            15693..16958
                     /locus_tag="JAM15_05010"
     CDS             15693..16958
                     /locus_tag="JAM15_05010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphate kinase"
                     /protein_id="HAT6797621.1"
                     /translation="MKKLPIKTVVQRLLNLQEEGKSATLLGIGPMSPNLLQASFELAK
                     DDDFPLMFIASRNQVDADELGGGYVNGWNQETFTKDIKKVADKVGFDGLYYLCRDHGG
                     PWQRDKERNDHLPVDEAMELGKKSYLADIEAGFDLLMIDPTKDPFEIGKVIPLDVVLE
                     RTVELIEYCENERKRLNLPDIGYEVGTEETNGGLTSTETYETFITRLKVELDNRGLPM
                     PTFIVGQTGTLTRKTEQVGTFNFRNAYDLAQMAKKYGVGLKEHNGDYLDDVTLLEHIP
                     SQIIATNVAPQYGTEETRAYLKLAEVECKLEKEGLVEKTSNIRHVLLVNAIECGRWRK
                     WVVGEQKNLTTEEIFKDEVLSNEILDIAGHYTFNNDDVKKEIEVLYDNLSKNNIDGQR
                     FVVDHIKRPLRDYAECYNLKGVTTRILNK"
     gene            17046..17762
                     /locus_tag="JAM15_05015"
     CDS             17046..17762
                     /locus_tag="JAM15_05015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAT6797622.1"
                     /translation="MINLIFDVDDTLYNQLTPFYTAYNKVFSSIKDISIEDLYMSSRK
                     YSDEVFHMTENGEMPIKEMHIYRIMKAFEELGNSITEKDAQSFQDEYIYQQSQITLIP
                     EVEMILNFSKERNINLGIITNGPSNHQRMKLKQLNIENWVDKSNIFISSEVGFSKPDT
                     NIFRVAENVMNLDRENTYYVGDSYRNDVLGAKKAGWKSIWLNHRGHEVEELFYKPDFV
                     ILEHKDLISLFIKICSYKNM"
     gene            complement(17957..18250)
                     /locus_tag="JAM15_05020"
     CDS             complement(17957..18250)
                     /locus_tag="JAM15_05020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012423205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein"
                     /protein_id="HAT6797623.1"
                     /translation="MRNMIENLIKNNTYIDDKVIMLSMLSSAKASANMYLNSALTSST
                     PELRAIYSASLTQMVEGHTALTELSINKGWVKPYDKPIQQLTCSYKESQNVID"
     gene            complement(18256..18471)
                     /locus_tag="JAM15_05025"
     CDS             complement(18256..18471)
                     /locus_tag="JAM15_05025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797624.1"
                     /translation="MRILSETEKISLAAVIKMESDGLLMQRAINMLISDEDLKRQSES
                     SILATEGRIKAIQQFIVENEILISEEV"
     gene            18919..19317
                     /gene="tnpA"
                     /locus_tag="JAM15_05030"
     CDS             18919..19317
                     /gene="tnpA"
                     /locus_tag="JAM15_05030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008932953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HAT6797625.1"
                     /translation="MYKSNKNIVYDCKYHIVFCPKYRKPVLVGEVEKMLKEILPYKAD
                     ELGAEIIEMETDKEHVHLLISCDPQYGIHKVVKGLKGFSSRVLRENFPHLKSSMPSMW
                     TNSYFVGTVGSVSLEVVKQYIENQQVRTKK"
     gene            19314..20477
                     /gene="tnpB"
                     /locus_tag="JAM15_05035"
     CDS             19314..20477
                     /gene="tnpB"
                     /locus_tag="JAM15_05035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family element transposase accessory
                     protein TnpB"
                     /protein_id="HAT6797626.1"
                     /translation="MIKTHRVKLNLTRTQFELVREKQMESANCWNYIVNLSKEYYFEH
                     KQWIKKNDIQKLIKGKYNLHSQTIQAISDKFDANRKTISELRKKGNTKAKYPYKTKKF
                     YIIPFKASAINRNAKGNLKLSMSKGRYLELDFNVENIKTAEIVWRNGYYLYYTFDNEL
                     NGVVAKGTNTVGVDLGEIHSIASVTNEGVGLILSNREGRSIKQFRNKMYAYISKRLSK
                     CKKGSRQSKKLWRLKNKIRSKTDNQLMNLYHQTTRKFIDFCVEQKVYEIVLGDIKGVE
                     KDTKKKKRLNRVNRQKISQMEYGRIKDYIKYKAKEQGIEVKLVKENYTSQTCPKCSKK
                     HKPTGRTYSCTCGYETHRDIVGAWNILNKKHKYGLVDFRINHKQPINLKVSTV"
     gene            complement(20861..21373)
                     /locus_tag="JAM15_05040"
     CDS             complement(20861..21373)
                     /locus_tag="JAM15_05040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAT6797627.1"
                     /translation="MLEVIKNRRSIRTYIDKNIEEDKITEILKSAMQAPSSKNAQPWE
                     FIIVDDKELLKQLSKSQHRAKHIEFAPLCIVVLGNRDKFLKPGKWIQDLGACTQNLLL
                     EVTNQGLAACWAGVFPKNKVVNKVRQTLDLPLKLVPYALISIGYSEEKNEFIDRFDEN
                     KIHRNVYKNR"
     gene            21823..22299
                     /gene="purE"
                     /locus_tag="JAM15_05045"
     CDS             21823..22299
                     /gene="purE"
                     /locus_tag="JAM15_05045"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HAT6797628.1"
                     /translation="MKVAVVMGSKSDYPKLEEGIKLLEKYGIEVVARALSAHRTPEQL
                     SIFLKEIEDDTDVIIAAAGKAAHLPGVIASQTLIPVIGLPIKSSTMDGLDSLLSIVQM
                     PKGIPVATVTIDLGLNAALLALQIMTLKYPKLKEDLKSYREEMAQKVLEDDKNLRG"
     gene            22305..23003
                     /locus_tag="JAM15_05050"
     CDS             22305..23003
                     /locus_tag="JAM15_05050"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HAT6797629.1"
                     /translation="MLLYEGKAKQVYSTDNENEYVVYYKDDATAFNGEKKAEISSKGI
                     LNNKISTIIFEMLKENNINTHFIKSLSDREMLVKKVEILPLEVIVRNIAAGSICKRVG
                     LEEGVVFDEPIFEISYKNDAYGDPMLNDDYAVAMKLATREELKFLREETLKINELLKA
                     FFLKLNLKLVDFKIEFGKDSEGNIILADEVSPDTCRLWDVNTNEKLDKDRFRKDLGDL
                     VEGYTEVLSRMNNK"
     gene            23015..24382
                     /gene="purF"
                     /locus_tag="JAM15_05055"
     CDS             23015..24382
                     /gene="purF"
                     /locus_tag="JAM15_05055"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HAT6797630.1"
                     /translation="MCGVLGIYSNKDVTKELYYSLYSMQHRGQESCGLALLDDGEIKY
                     KKDMGLVGDVFKENELSKLKGNIGIGHVRYSTAGGSHVSNCQPLVGSCRKRQLAIAHN
                     GNLVNANYLKDMLEEDGYMFQTNSDTEVILYILARYYKGDIVESLKVTMDYIKGAYAL
                     VIMSQEELVAVRDPHGFRPLVLGKKGDEYIFASENCAIDILGGEVIRDVEPGEIIVVK
                     DGELKSYFYSENYKPVKKSCIFEHIYFARNDATIDNVNAYEFRIKCGERLAQNETVKA
                     DMVVPVPDSGWPGAIGYANASGLKISEGLVKNRYVGRTFIKPTQEEREIAVKIKLNPL
                     STIIKGKSIILVDDSIVRGTTSKQLVKSLREAGAKEIHLRITSPPVAYSCYYGIDTPN
                     RSKLIASSNNVEEMREYIGCDSLKFLDIEGMLDATEHKSTFCKACFDGEYPVKKIDKE
                     ELLSC"
     gene            24376..25452
                     /locus_tag="JAM15_05060"
     CDS             24376..25452
                     /locus_tag="JAM15_05060"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HAT6797631.1"
                     /translation="MLTYKESGVDIDEGNRAVDLIKGKIKGTYDGNVVGDLGNFSGLY
                     SLKDFVGMKEPVLLASTDGVGTKLKIAQMMDKHDTVGIDLVAMCVNDLICQGAKPLFF
                     LDYIALGKLVPEHIEKIVGGIADGCKMSGCALIGGETAEMPGMYGEDDYDLAGFSVGI
                     ADKEKIVSGNNVKSGDVLVGISSSGVHSNGFSFIRKIFLETYNYKMEQYVEELGMTVG
                     EALLTPTKIYVKLALDVLAKHDIKAIAHITGGGLIENITRVIPKGLGLDINKKSWEKP
                     PIFKMIEGFNAVDERELHKSFNMGIGLVLIVDKENADDVVNFINNRENDNADYVDKKY
                     SELLEDKAYIIGEVVDSHEGVELC"
     gene            25446..26039
                     /locus_tag="JAM15_05065"
     CDS             25446..26039
                     /locus_tag="JAM15_05065"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HAT6797632.1"
                     /translation="MLNIGVLISGGGTNLQAVIDGTESGEIKGQVKVVISSKQGAYGL
                     ERAKNHNIKAICETDEDKIIEILKENKIDLVVLAGYLKIISPKLVNEFRNKMINIHPS
                     LIPSFCGAGFYGEKVHQGVIDYGAKVTGATVHFVDEGADTGPIIMQDVVKVNQDDDAK
                     TLAKRVLEVEHRILKESISLFCENKLKLQGRRVFINE"
     gene            26032..27564
                     /gene="purH"
                     /locus_tag="JAM15_05070"
     CDS             26032..27564
                     /gene="purH"
                     /locus_tag="JAM15_05070"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HAT6797633.1"
                     /translation="MSKRALISVTDKTGVVEFAKELNKLDYEIISTGNTFKTLKENGV
                     NVMQVEDVTNFPEILDGRVKTLNPYIHGGILYKRDKESHVETVNEHKIHSIDLVAVNL
                     YDFEGTLKAGKSHDEIIENIDIGGPSMIRSAAKNYKDVIVVVDIKDYDSIIEKLKTDT
                     MTLEDRKKLSYKAFSTTGRYDALISSYFAGEVGDTYPDILNLTFQKEQTLRYGENPHQ
                     NGFLYSQSNAKNPILNYEQLGGKELSFNNLNDLHGCLEVMREFKDSEEVVSVAIKHAN
                     SCGVGLGKDAFEAYTKCYEADKVSIFGGIVGITSTIDKATAEKLNEIFLEIVVAYDFE
                     PEALEVLKQKKNLRILKLAKIEDSLQPYEMKYLDGKLLIQDRNNILAEKSENVTKAKP
                     TDAQLKDMEFGMRVVKNMKSNAIAIVKNGQTLALGCGQTSRIWALKNALENNKDKDFT
                     GAVLASDAFFPFDDCVTLAHEYGISAVVQPGGSIKDKDSIEACDKYDMVMVFTGIRHF
                     KH"
     gene            27575..28825
                     /gene="purD"
                     /locus_tag="JAM15_05075"
     CDS             27575..28825
                     /gene="purD"
                     /locus_tag="JAM15_05075"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HAT6797634.1"
                     /translation="MKILVVGGGGREHAICWKLSKEKNVEKVYCAPGNAGITNVAECV
                     NIGDTNIEELLKFAKENEIGLTIVGPEVPLVMGIVDEFEKEGLRVFGPNKKCAQLEGS
                     KAFSKEFMIKHNIPTAKYKEYTNLEEAISEIDSFGYPVVIKADGLAAGKGVVIPENRE
                     DAIATLKEMMSDKKFGAAGDKIVIEEFLKGIETSILAFVDNDTIVPMASAKDHKKVNN
                     YEQGPNTGGMGTFSPSEIYTEELANKVKETVLEKTLEGFKKDGLNFKGILFVGLMITE
                     DGEKVLEYNVRFGDPETQSVLFRLETDLHEIMETILDNKLKDIEINYSDDEAVCVMLT
                     SGGYPDSYEKGKIITGLENLDDDIVVFHSGTKMLDGNLVTNGGRVIGITAKSTTVKDA
                     AEKVYENIKKINFEGMHYRTDIGR"
     gene            28850..32656
                     /locus_tag="JAM15_05080"
     CDS             28850..32656
                     /locus_tag="JAM15_05080"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HAT6797635.1"
                     /translation="MLNTENKDSMVRRVLVEKREGFDLEAKALKKDLVESLHIDNIEN
                     LRILNRYDVEGISEEVYENAAKTIFSEPNLDVVYYEEIPKLNDERIFAIEFLPGQYDQ
                     RGDWAAQCVQIVNQGIRPTINTAKVYILSGKITDEEFSKIKDYCINPVDSREASLEKP
                     ETLKMETEIPTTVEVLDGFIDLDENGLRTFVSEKGLAMTLGDLQHVQKYFKDTEKRNP
                     TITEIKVLDTYWSDHCRHTTFMTEIENVKIEDGKFNDIVKEAYQMYLNSRDNVYVNRH
                     KDICLMDIATVAVKELKKNGKLNDLDESEEINACSINVDVEVDGKMEKYLVMFKNETH
                     NHPTEIEPFGGAATCLGGAIRDPLSGRSYVYQAMRVTGSADPRTTLEDTLPGKLMQRK
                     ITTEAAHGYSSYGNQIGLTTGQVAEVYDENFVAKRMEIGAVIAAVPKENVVRERPEAG
                     DVIVLLGGKTGRDGCGGATGSSKEHSEESILTCSAEVQKGDAPNERKIQRFFRNKEVA
                     QMIKRCNDFGAGGVCVAIGEIADSLDINLDLVPKKYDGLDGTELAISESQERMAVAIK
                     KENKDKFIQLAVEENLEATHVATVTDTGYLRMFWNGKAIVDINREFLDTNGVKQTTDV
                     HVTKVDEENTFFSSNEIVKDVKCASMKDKFTKVLSDLNVCSQKGLVEIFDNTIGGNTV
                     LMPFGGKYQATPTQGMVAKIPVLGGETNTSTIMTYGYNPKVGKWSPFHGALYAVVESV
                     CKLVAIGGNYSTTRLTFQEYFEKLGNNPEKWGKPFSALLGAFYAQSKFEIPAIGGKDS
                     MSGTFKDIEVPPTLVSFAVDTVDAKKVVSPEFKKADSKVVMLCVNKAENDVVDFEELK
                     RNLDKVRELIHGNKVLSTYALGFAGVGEAISKMAFGNKIGFKFSEEAEKTFTDDKLFE
                     ASYGNIVLELANDDLCMLEGYNYVVLGSTTKEASIFIKGEELALDELYKAHCSTLEPI
                     FPTKTEEVKSKIETISYISQGEAKKSSLSIVTPRVFIPAFPGTNCEYDSARAFERVGA
                     NANIRVFKNLTYKDIEDSIDTIVNEIKSSQIIMLPGGFSAGDEPDGSGKFIATVFRNP
                     RVQEAINEFLTQKDGLMLGICNGFQVLIKLGLVPYGEIRVPSESAPTLTYNNIGRHQA
                     KIARTRISSNKSPWLAQTNVGDIHNIAISHGEGKFVASEDVMRELIANGQVATQYVDF
                     NNEATYDIEFNPNGSFYAVEGITSADGRVFGKMGHSERIGEEVFKNIIGEKDQKIFES
                     GVKYFR"
     gene            32862..33734
                     /gene="rfbD"
                     /locus_tag="JAM15_05085"
     CDS             32862..33734
                     /gene="rfbD"
                     /locus_tag="JAM15_05085"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HAT6797636.1"
                     /translation="MKILITGSNGQLGKELVNQLEAINQSINQPKYVILATTRSDLDI
                     SNQTNVDNFILHNKPDVVVNCAAYTKVDACEDNIEIAYKINALGVRNLAIASEKVNAK
                     LIHISTDYVFNGFSKYPYKEDNKTEPNSVYGKSKLMGEKFVEQFSHKYFILRTAWLYG
                     NGNNFVKTMIKLSLENKEVNVVNDQFGTPTSTVDLAKIIIRIMETEHYGVYHATCEGE
                     CSWYDFAKKIFELKNIDIKVNPIKSNEFKCKAQRPLYSVLDNFMLKLIGLNSFRKWEE
                     SIEEYLERYDINEK"
     gene            33843..34724
                     /gene="rfbA"
                     /locus_tag="JAM15_05090"
     CDS             33843..34724
                     /gene="rfbA"
                     /locus_tag="JAM15_05090"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HAT6797637.1"
                     /translation="MKGIILAGGSGTRLYPITKCISKQTLPIYDKPMIYYPMSVLMLA
                     GIQDILIISTPRDIKAFEELFGDGSSLGLKITYAIQEKANGIAEAFIIGEEFIGNDRV
                     SLVLGDNIFYGYGFSERLENAVKRKGATIFGYHVSNPNSFGVVEFDKDFNVLSIEEKP
                     TVPKSNYAIPGLYFYDNDVVEIAKLVEPSDRGELEITSINSEYLKRGKLKVELLGRGM
                     AWLDTGTHKGLLDASNYVEVVQTRQGLYIACLEEIAYTKGYISREQLMKLAKPLIKTE
                     YGQYLLKLASEDMQYGR"
     gene            34761..35318
                     /gene="rfbC"
                     /locus_tag="JAM15_05095"
     CDS             34761..35318
                     /gene="rfbC"
                     /locus_tag="JAM15_05095"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HAT6797638.1"
                     /translation="MGKINVIKTKIEGLYIVEPNVFCDERGYFMESYNKKDFIEQGLD
                     MCFIQDNESSSRKGVLRGMHFQVRYPQGKLVRVTEGEVFDVAVDLRKDSQTFGKWEGV
                     ILSDKNKKQFYIPEGFAHGFLVLSEKAVFNYKCTNYYYPEFENGFIWNDKQISIEWPL
                     KGIEEIFLSEKDKKQKSFRDICTRR"
     gene            35356..36339
                     /gene="rfbB"
                     /locus_tag="JAM15_05100"
     CDS             35356..36339
                     /gene="rfbB"
                     /locus_tag="JAM15_05100"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HAT6797639.1"
                     /translation="MKKILITGGAGFIGSNFIHYMLNKYVDYFIVNLDLLTYAGNLET
                     LIEIQDNSNYKFVKGDISNREQVYKLFEEERFDIVVNFAAESHVDRSVENPDLFIKTN
                     IIGTQVLLDASIKYGVKRYHQISTDEVYGDLPIDRKDLFFTEQSPINPSSPYSASKAS
                     ADLLVSSYYRTYGLLTTISRCSNNYGPYHFPEKLIPLMILNALENKQLPVYGNGENVR
                     DWLHVYDHCTAIDLIIHKGNIGEVYNIGGHNERSNLEVVKMILNLLGKSEELISYVND
                     RPGHDLRYAIDATKIENELGWKAKYDFDLGIKETVKWYIENESWWKAVLSV"
     gene            36369..37037
                     /locus_tag="JAM15_05105"
     CDS             36369..37037
                     /locus_tag="JAM15_05105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HAT6797640.1"
                     /translation="MNEISSLINILALTQLSGSNTTNQCNCTYNNSSGFDMIMMTLLK
                     ALSQNNQHTSNSYNLLSNSENLFNELDNVVNNTTSRFIDVDTKDKNVKLRIENAVEQA
                     SKKYNVDSNLIKAIIKVESDFNPNTVSSAGAKGLMQLMPENCRDLGVTDPFNIEQNID
                     AGTRHIKEYIDMFGGSIEMGLMAYNGGPGRMKSRGVESISDLYKMPKETQNYIPKVMK
                     YYRG"
     gene            37046..37474
                     /locus_tag="JAM15_05110"
     CDS             37046..37474
                     /locus_tag="JAM15_05110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaaR family protein"
                     /protein_id="HAT6797641.1"
                     /translation="MGINIDKLNISPSINMEVKKLKESNKFSDKLNSLKQSSSLEDIK
                     RNLESVKKAGERLVLTQNYGDISIYKNAVKEYLKSVVDNMYSLDKNSSFWEHQYYKNV
                     KIVDSKLEDMTSKLISEEKENIDIVSTVDMIQGLLIDMYR"
     gene            37498..37812
                     /locus_tag="JAM15_05115"
     CDS             37498..37812
                     /locus_tag="JAM15_05115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HAT6797642.1"
                     /translation="MNSKKEDIYELNFGQLIEEKSGVIEENQNVFNAKVNVAVSIGNT
                     TETIKNILDLKEGSIIKLSKNVDEKLDIYANDRLFAYGESIITNEKLSVRLSKIEDSD
                     VN"
     gene            37964..38239
                     /gene="flgM"
                     /locus_tag="JAM15_05120"
     CDS             37964..38239
                     /gene="flgM"
                     /locus_tag="JAM15_05120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis anti-sigma factor FlgM"
                     /protein_id="HAT6797643.1"
                     /translation="MDIKNVSSNIVVNNYLKNTSGVKKVEEVKKINKTDKIELSKFAK
                     EMASVSNMSDENIRNKKVDEIKNALENGTYKIKPKEIAKKMIEDMRG"
     gene            38244..38660
                     /locus_tag="JAM15_05125"
     CDS             38244..38660
                     /locus_tag="JAM15_05125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlgN"
                     /protein_id="HAT6797644.1"
                     /translation="MITDLKVIIYEEKNIISKMMELLKEQFDYIVEKDLENLNMLNPK
                     LEDISRELASIEIKRRQLFGDDISMSEVVENSNDGYLKEIYTDLKHILALAKNQQESN
                     DSLIKKELIFTKKMINFIKPADKQTTTYNSYGNIRK"
     gene            38678..39988
                     /gene="flgK"
                     /locus_tag="JAM15_05130"
     CDS             38678..39988
                     /gene="flgK"
                     /locus_tag="JAM15_05130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgK"
                     /protein_id="HAT6797645.1"
                     /translation="MAGLFSILNTANSGMNAHQKAIQTISHNISNLDTDGYSRQRTEF
                     ATNSPMYMPSLSNSIARGQLGTGVHVTDVTRARNSFYDYQFRAEAHKYGNTVSKYDYY
                     NTIETILNEPSDYGISAGIDDFFKGWESLSKDINSDSKKSLVVENASNLATLISESYK
                     KLDKLKEDIDSNIDTEIKQINDMLKSLEDLNKSIDIISGSGSTPNDLLDERDRILDNL
                     SFKLDFENSDVKNILADGKLELNELKNPDGTWKTGVSGTLQGLFEMHGKIDTYKSDLK
                     DVSDGLAKQINDVYNTSAGITVTDFFITSNVDGEDIIKINPAIKSNPNELKLTADEAS
                     KIAKLKDEKIDIGVAGGKVSTISDHYKAFAESIGLDSQKVNQDEANQRKIINNIDNSR
                     MSVSGVSLDEEMTELIKIQRSYQASAKVMSTAVQLLDVVINGII"
     gene            40007..40939
                     /gene="flgL"
                     /locus_tag="JAM15_05135"
     CDS             40007..40939
                     /gene="flgL"
                     /locus_tag="JAM15_05135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein 3"
                     /protein_id="HAT6797646.1"
                     /translation="MRVSTGMMSSSYLNSLQDNLQRLDKVNRQVNTTKEINKLSDNPY
                     KAIKILNSKSEIKTMETYVENCKDTGNWLETTDTALDQLGKLLSDIKKTLVASGDGAY
                     SDDELKTLSNETNEKMKEIANALNATHEGKYIFSGSNTGVPPVECIDNADGSVSLKFN
                     SSLNLNKLNDSLSMDIAQGISVDYNVKLSSLGFDPTKTDPFEELNNISKKLANPDADA
                     IKELTTTCLGDMEQLIENTVNVRSIYGTKANTVEAMKEKNDDSLIQLKDILSQNEEID
                     YGEKLVQLKAAELTYQASLQTGGKLFNVSILDYI"
     gene            40955..41347
                     /locus_tag="JAM15_05140"
     CDS             40955..41347
                     /locus_tag="JAM15_05140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliW"
                     /protein_id="HAT6797647.1"
                     /translation="MMKVTLKKGILGFEDLKEYELLDIEDNDSLKEFNSTEEEGIGFV
                     VVSPFEIINEYEIVLNQETIEKLEVKSPKDVVLFNIITLGQTFEESTVNMKAPIVINI
                     KTNFGMQIILQDDKYSIRHPLLRGDNGC"
     gene            41341..41553
                     /gene="csrA"
                     /locus_tag="JAM15_05145"
     CDS             41341..41553
                     /gene="csrA"
                     /locus_tag="JAM15_05145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon storage regulator CsrA"
                     /protein_id="HAT6797648.1"
                     /translation="MLVISRKKDEAVLIGESIEVKIVGVDGNNVKLAISAPNNISILR
                     KEIYEKVKSENIKATNKNIKILKSLK"
     gene            41575..41970
                     /gene="fliS"
                     /locus_tag="JAM15_05150"
     CDS             41575..41970
                     /gene="fliS"
                     /locus_tag="JAM15_05150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HAT6797649.1"
                     /translation="MYGENPYNSYKQNAVFMASKEQLLLMLVDGAVKYTKIARAAILD
                     KNTQKAHRELVRVQDIFTELMVTLDQNAGQWAKDMYKVYDFVRYELSRANIRKDIQVI
                     DNVLPVIEQIKDTWHEADKKSKEERSRYK"
     gene            41970..42326
                     /gene="fliS"
                     /locus_tag="JAM15_05155"
     CDS             41970..42326
                     /gene="fliS"
                     /locus_tag="JAM15_05155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HAT6797650.1"
                     /translation="MELNLAELDKLSKEELLLMLVDGTVKYTNISKDALLNNDYLKAH
                     NELVRVQNIFTELMTTLDQDAGQWAKDMYKVYEFIKSELAIADENKDIKIIDDILPIV
                     KQIRDTWHEVYNQLKI"
     gene            42347..43870
                     /gene="fliD"
                     /locus_tag="JAM15_05160"
     CDS             42347..43870
                     /gene="fliD"
                     /locus_tag="JAM15_05160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar filament capping protein FliD"
                     /protein_id="HAT6797651.1"
                     /translation="MSSISPIRVTGLSGNFDMEGIIEASMIRDKEKVDKAKQEQQIVK
                     WKQEIYRNVIQESKDLYDKYLSVNSPNSIVSEKAYSSTRITSSDESIIVAKGSAGAEK
                     INYQFAVSQMAEPAKFTIKLNSSEPIVRQFPPNASGASSLTIGDVNIPISEQDTTSTI
                     VSKINSLCADNDIKASYSEMTGELIISRKQTGSSSDINLKVIGNDNLAQQIANDNGVT
                     FTNDASGNKVASVYGKNLEADVTDEHGRVTHISKEQNSFNIDNIDYNVNSKGTAKLTS
                     VTDTEEAVKNMQAFVDDYNKLMDKVYGLVTTKKPKDYPPLTDAQKEDMTTEEIEKWEK
                     KAKEGILRNDDELRGFVEDIQSAFFGDGKNIIALRKLGINESENYNKKGQISFNADTF
                     SKALIDDSDKVYKTLAGYSSNYDDKGMFEKLKDIVYEYSGSSTSKLPKKAGIEKTASA
                     SENVYSKQIAEQERNISRLVEKMNDKEKRLYAKYSALESLLNQYSSQMNYFSQAQGN"
     gene            43873..44208
                     /locus_tag="JAM15_05165"
     CDS             43873..44208
                     /locus_tag="JAM15_05165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliT"
                     /protein_id="HAT6797652.1"
                     /translation="MDKLKEKLNLYKDISLQIINLIEKEEYIKISSKLGERQEIINSV
                     SEIDRNDFIQLYNRMELIEIDSRIRDILQGQLLEIKKELHEYKLTKQVNTMYYNLNRE
                     KVNIFNKKV"
     gene            44310..45182
                     /locus_tag="JAM15_05170"
     CDS             44310..45182
                     /locus_tag="JAM15_05170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin"
                     /protein_id="HAT6797653.1"
                     /translation="MRVNTNVSALIANNQMGRNVNAQSKSMEKLSSGVRIKRAADDAA
                     GLAISEKMRAQIKGLDQAGRNVQDGISVVQTAEGALEETGNILQRMRTLSVQSSNETN
                     TAEERQKIADELLQLKDEVERISSSIEFNGKKLLDGSSTEIRLQVGANFGTNVAGTTN
                     NNNEIKIALVNTSSIMSKAGITSSTIASLNADGASGTDAAKQMVSSLDVALKELNTSR
                     AKLGAQQNRLESTQNNLNNTIENVTAAESRIRDTDVASEMVNLSKMNILVQASQSMLA
                     QANQQPQGVLQLLG"
     gene            45275..47416
                     /locus_tag="JAM15_05175"
     CDS             45275..47416
                     /locus_tag="JAM15_05175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAT6797654.1"
                     /translation="MLLSIVMIVKNEEKILEKTLKSLTTLRSSIESELIIVDTGSTDD
                     TIKISKKYTEKVYFHNWNNDFSSMRNISISYAKGEWLLILDADEILIDSSTIVKFFKD
                     GLDKKFNSASIQLKNLYSYDKKLYGYCSVLRLFKNVDFRYHGKVHEQPIYKNPIFNNV
                     ADFEHYGYLFEDEEIRLNKVKRNEKLLFEELKENDNSPYTNYQLGKNFIILGKYHEAL
                     YYLEKSYELYSKLESAPGYLITSLVKTYLYLGKHKKCERLCLKYIKKDMNNIDIYYYI
                     AQAQVDLGKYENSIDSYKRYIYLLDNYEISTQANSLFSDTDTVGLKDEAIITLIKIYY
                     KLEKYESVISEYNNIEDMEKKKNVYFSLFMSLYKLNRFEDIKNYYKEVSNSKIEKNSF
                     YRNIEEVINNIKEDEKEYVYKILCDIEGNYGILNQIRINKCVSIDKCKEILNEEKEII
                     YAYIIKIAFEEKIDLLDIFYEMEYVWIEKYLKYLLALERSFNLVLYKYIISRPNTSDM
                     EKIRVYKAISKVVLESISLSDEKYKEIFYLYIMYSYKYIRYIYNNLSDFELIKFVCND
                     LDKFTIEFKHLLDIKNKVNDANEKLEYIHSMRKLLNEYPFYNKIIKILIGELEENIKE
                     SEEFKDLKDSFIISIENMIETGKINDAKLLVDDYSKTFVDDVKILNIKGILYMFENKL
                     DKADFMLKKALSLDVENEDTIYNIEYLKSLR"
     gene            47440..49317
                     /locus_tag="JAM15_05180"
     CDS             47440..49317
                     /locus_tag="JAM15_05180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAT6797655.1"
                     /translation="MNTPIVVNEKSKDIIKDWQYKCTNEDIKFTSIIILTYNQIEYTK
                     LCIESIRKFTPKNKYEIIIIDNNSSDGTVEWLKGQSDIKSVYNNKNLGFPKGCNQGIE
                     LATGENILLLNNDVIVTPNWLYNLNKALWSQDNIGAVGPITNACSYYQQIDVDYKSID
                     DMFMFAHKINKSNINLWKYRLKLVGFCMLIKKSVLDNVGVLDELFTPGNFEDDDLSFR
                     MIESGYKLLLCQDTFIHHFGSMSFKENRNKYIDIMYINRRKFETKWGFNPEYSGMIRT
                     DLISKIDDSLEENINVLEIGCGIGATLLEIKNIYKNASTYGIEISESAGKLAKYSADV
                     LIADIEKVKLDYEKDFFDYIILGDVLEHLTDPWKIVNELKQYLKKDGCLISSIPNIMH
                     VSVLRNLVLGNFTYEDSGILDKTHLRFFTLNEITKMFNDSNYIINSVTATSMPLSEID
                     NRFIDTMCKESCKEMRQQYESYQYIVKATKSIDTKRYSSISMINLKYALMRIDNELDV
                     DSNLSYIFDNYNITEPCFVDDIEYLVDTFVINKATLLNRLGVEAFNRGLGDFSINMFM
                     TVLEMDRDDIDSIYNITSVLCELEEFDTAYNLIKNSSEKVQVESDIQEILCFIEGKRY
                     E"
     gene            49310..51424
                     /locus_tag="JAM15_05185"
     CDS             49310..51424
                     /locus_tag="JAM15_05185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HAT6797656.1"
                     /translation="MNNDKICFITCVNDERLYEECLVYINSLDIPKNFSIETVALRGA
                     DSIASAYNKAMRETDSKYKVYLHQDTFIINKNFIYDILEIFKKNTDVGMIGVAGVKDI
                     PVNGIWWDSDKKVGKVYDSHTGKMDIYEFSNFEERFNEVMAIDGLIMITQYDVFWRED
                     KFDGWHFYDLSQSMEFRQNKYKVIVPKQNKPWCMHDSGVANINNGYDEYRIKFVKEYI
                     NLDLYRENFYEFDKKKASTILKSNKHVMDCMKEELTEQLRLKNYKNVLDIVSKIAHFS
                     VFNHTGLYSCEKCERALLECANNLPEIENTKLFTKKDLKRRKVLHVLSEGYSTGGHTR
                     LVKNWIEIDKDSVHSVVTTWQSDTLPDWLLKAIDDSGGEIISLDLISDDYLKRAMALR
                     KIAYDWADIVILYVHMWDTIPVVAFGVDGEIPILHVNHYDSTFWLGTSIADIVIDFSE
                     ASQLITLDKRGIDKSEILPMPLKEKEVFSKSEVRKRYNLEEDVTIILTIASERKYNSV
                     NDINYFKIVKTLIENTDNTIIIVVGVDTENLYWKTLSNVTDNRVICFGTTTNIDDFYK
                     ISDIYMESFMVGSHTSKLDAILYDLIPVKFKNEVSPIFTNMWNFIDKFDYKNIKEVID
                     MIKRYNTSEFDRDKIKEKQSEIKHFVIDKHCIEIKNYIDKIYNEANHHKVKYDLYKND
                     EIEDYQLFVALYGYMVKNKNMS"
     gene            51433..52428
                     /locus_tag="JAM15_05190"
     CDS             51433..52428
                     /locus_tag="JAM15_05190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation glycyltransferase
                     FemA/FemB family protein"
                     /protein_id="HAT6797657.1"
                     /translation="MNNIHINKFEKSCEKNWDYFVENKSINGTFLQTRNFLNYHEEGK
                     FTDHSLIIYKGEEILAVVPACETYENGERVFFSHLGSTFGGIIIRSGFNDIRHVNAIT
                     NKLETYLQEQSFNKVYLKNTSRIFCKEDTSLLEYFLFKNNYMFYDELSMFLELSKYKK
                     DILANFRYSKRRYFKYSLKNNLTFKRLYSDEDIVCFFNLLSNCLDSKGAKVIHSVEEL
                     LEFKNNRLKDIVEFYAVYIDDIMICGSMVFNFQERVYHTQYLASNSTYNKYYPMIFLY
                     YNLIKDALERNFKYLSFGISTLNRGKYLDEGLATFKEGFGSSAICNRTYYKNINK"
     gene            52520..53752
                     /locus_tag="JAM15_05195"
     CDS             52520..53752
                     /locus_tag="JAM15_05195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HAT6797658.1"
                     /translation="MKRLMILGSIKYFENIVISAKKEGIYTIVCDNRIDTPAKKICDE
                     AIDVDVFDFDKIKSIAIDKKIDGILTGFTDSLMKPYVYIANELNLPCVISCNQLESVT
                     NKAIMKKYFKNNAIPTTDYCIIESLKDLEKIQGLNFPLVIKPVDGYGSRGVYFVSNIK
                     ELIEKFEYSKEASQDGQVIIEEFYESEEIQGLAWVHNGESHVFYIGDRELVNIHTGRA
                     GKPDRLLYPSKYCFQYEEEIKSIYQNITQAFDIKNGPLYVQMLVGAYGIKVSEVMPRL
                     PGGCDYMAISQITDLDIGSLFANFSVNNEVNFDEIKKYNMHLSKCVYALPIYIRPGTI
                     KKINNVDKIENLDYVTQFLLLVKEGDTIGLYEDERQDCGRVYGIANNIFDANIKKKCI
                     HEMIEIFDENNENMIENF"
     gene            53772..54716
                     /locus_tag="JAM15_05200"
     CDS             53772..54716
                     /locus_tag="JAM15_05200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase"
                     /protein_id="HAT6797659.1"
                     /translation="MKLITHEQIMSLNISQKQGYEWIKESFLTKKDCQLPPKISMVEE
                     GHVFYNVMPSLNHNHMIGGIKMVTRLPGRNPSLNSDIFLYNMKDAKLKAILDGNYITA
                     FRTAAVAGLAIDTFAKKDFNTISIMGLGVTASAIMNMLSYTLKDKNINIKLLKYKDQA
                     ESFVKKYEKNEQFSFEICDTHEELIVDSDVVISTVTYTDEYLSEFKWFKKGALLLPVH
                     VMGFGNVDYLFDKVYLDDYNHLKHLENIDRYKYSCEFYDVLSKQAKGRENDDERIISY
                     NIGLSIHDILFANKIYELCETLNCEEIELKEPKEKYWI"
     gene            54810..55217
                     /locus_tag="JAM15_05205"
     CDS             54810..55217
                     /locus_tag="JAM15_05205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxcM-like domain-containing protein"
                     /protein_id="HAT6797660.1"
                     /translation="MDKYNLIKFLSIGNEYIGNLVALESNKAIPFDIKRVYYIYDVPN
                     NVKRGFHAHKNLEQVLVCLNGSVKIKCYDGVKESIFNLHKNDVGLYIGTGVWHEMFDF
                     DEKTVLISIASEHYNEEDYIRDYKEFLKYLNNM"
     gene            55304..56395
                     /locus_tag="JAM15_05210"
     CDS             55304..56395
                     /locus_tag="JAM15_05210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HAT6797661.1"
                     /translation="MLVKFNNLLKQFQIHKEEYEQKIKDVMESGYYILGNEVRHFEEE
                     FASYVGSKYCVGLASGLDALIIAFRALGISEGDEVIVQSNTYIASVMGISINGATPVF
                     VEPNEYYNIDSSKIEEKINSKTKAILVVHLYGQASKMKDIQELCDKYNLYLIEDCAQS
                     HGAKYDGKMTGTFGDIGCFSFYPSKNLGAFGDAGAIVTSNEEIADKVKILRNYGSEKR
                     YYNKFVGYNSRLDEIQAGLLRVKLKYLNEIEIEKSKIVDRYLNEINNPKVILPKIENN
                     CTHVWHLFVLQVEKRDTFMEYLKKNGIESIIHYPIPPHLSEAYAYLGYKKGSFNIAEN
                     YSDKVVSIPLFVGMEDEEVSYIIKIINEY"
     regulatory      56704..56794
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
BASE COUNT        22533 a         6076 c         9995 g        18347 t
ORIGIN      
        1 gcttatggga ttcaagaaat tgccagattc tgagttaaaa gtaatgaaat ttatttgggg
       61 attagataaa aataaggtag catcaggaga agttgtggaa gcaatgaaac aaatttatga
      121 ctggaataaa aatacaacat taacaatatt gtctaagctt gcaaagaaaa actatttgta
      181 ttctcaaaaa acaagcaagt gtacatatta tactatcgct gtaagggaaa aagattattt
      241 aaaagttgaa acaaaaaaat tttttagttt ttttcataat aattctttaa aaagtttttt
      301 cactgcttta aatgacgaag aagacttaag tgatgataaa ttagatatgt tagagcaatg
      361 ggtaaaaaat tgggaagagg atgaataaaa tgaatgtgat actaaaatga tactaatatg
      421 ttttatagcg tgttaaaaaa tatagaaata atagaaataa tagaagaaaa ttcatgtaat
      481 agatgaggtt ttatcagatt aaaaagaaaa acaatagaat gggaataaaa tatagaatgc
      541 caaaaatcca catgaataca ggatttgagg tctctcttac ttctatatta tactggtttg
      601 atactatcaa tatttgccag tatcttatgg attaataagc aaaaaacatc ctgctgaatg
      661 gtaaattcgg cagggtgttt ttattttgtt ttagaactcc tttgctctga aactcgaagt
      721 atttaacact gatgatgttg ttatctttta gttccttttg tgtcatgctc tgaaagacaa
      781 attgatacaa taaaaaagta atttcttaac cattgatgga gatatgtact tatgttactt
      841 ttgatagtaa tttgagtaat attgttcata gctttttata ttcacttaat tagaaaacca
      901 tttgatataa tcataaataa acttgatgat ataatagaaa agatttataa ttattagaag
      961 tatataaaag tattttatgt ctatgaaatg tatgtatata aaacatatag atgacttttg
     1021 tatattaatg tatgaatatt gatactatag aagaattgag ttgtcaatga tactaaatca
     1081 aatatttata gaagatggag ggattatgag aaataaaata attataggaa ttactttttc
     1141 acttgtatta ctaatgtctg gatgtgcttc aaaacaaaca gcagaaataa acgtattagc
     1201 aactactgat ttacatggag ttatacctta tgagttaact tcctatgtaa aagaagaaag
     1261 aaaaaaagat aaaaatctaa ctttagtaga tgcaggagat ttttttgata gtggcgaagt
     1321 atctggttct agcatggata gttattttag tgctaggtat aaggatattg ataataacac
     1381 tgagcgttac attgagacac ctatttcaaa agatatgaaa gaggtaggtt atgatgttgc
     1441 agttcttggg aatcatgaat ttatatccaa caataaattt tatctagata atatgatatc
     1501 tgattttgag aaacaaaaaa taaatatttt atcggcaaat acgtataaaa aaaatggaga
     1561 tagttataca aaaccataca taataaaaaa tattaataca cctgaaggaa acgtaaaact
     1621 aggaatttta gggcttacta taaaagaagt tggtgagagg aaacagtgga aagatggaaa
     1681 acttgttgac tctaagtctt tagaactaaa agaccaagag ggttacaatg gtgaattgta
     1741 tatgaatgat ttagtagaag atgctaaaaa gtgggttggt ataatggaaa aagagaagcc
     1801 tgacattata gttgctgtgg cacatacagg tgagaaacct aagaaaccta aaaacccagg
     1861 aaatagaata caagacttag ctcaacaagt tgatggaatt gatgctatag ttgcaggtca
     1921 taatcatgtt caaattgagc aacatgatta taaaaataaa tcaggagaaa atgttatagt
     1981 tactgagcca ggaaagcatg gagaatgcat ttctaagatt aattttaaat tagaaaaaaa
     2041 caatgataaa tggaatatag ttgacaaatc tagtaaatta attaaatttg aaaaaaatca
     2101 agaaagtgat aaatttggag aatttatttc ttcaattaat aaagtaagta aagataagaa
     2161 agaaataaga ttatcagaag taaagactcc tgaatgggat aaaatatatg tttttaaatc
     2221 tggaacatct gcagatgata tatataaaac aataggatac aaatggagaa atatatcatc
     2281 tccaaagggt gatgacatgg tgcagattgt tgtaatgaat aataataagc ctgttagcta
     2341 tgtatatggt gaagctgaag ttatgccaat taatataaaa tgtgatgaat cagagtataa
     2401 agataatgtt gtaactattt atcctaataa aaatgataaa tttaaaattg aaaaaggtaa
     2461 acaagaatat agtattaatt taaaacatat acaatagaaa cttttatctt atttaagttt
     2521 agattgtact taaaataaag tgtgtattat tttaaaaatt gatgataatt aaaatcacaa
     2581 cattaaggaa tagtacacac tttttatgct aaaaaataga atgttaaaaa attaaacctt
     2641 taaattaaag tacattgctt atattatcca atattatctt caaaggttgt gtaatatttt
     2701 tatccttatg taatattgct aacattttat tttccatatc tatcccatct aattcaatca
     2761 atcacaattt tttatgaaag agtgaatcta ataataaatt ttctggcaaa atggttatac
     2821 ctaaccctgc ttctgcagct ttaataagtg caaaagaatt aacactttcc caaacaggat
     2881 aagctttttg gtttgaaaga gataatacac tgtccaaagt atcgcgaatg gcacttcctt
     2941 gctcacgtaa caataacgga aacgtgcata actgtcgtag agataaggct tgtttagata
     3001 aaggaaaagt tggagcacat gcaacacata acttatagga acctaataaa attgtacgga
     3061 atgccccctg tggttctata ccttcccaaa aacatatatc agcttctcca ctttttaaaa
     3121 tatccatagc tgaattagca ctttcgacac gtacattcac tttaagagat gggaatgaat
     3181 tttttagtcg acttaaaatt ggtggaagta aaaaagaggc aattgtaatg ctagaaacaa
     3241 tgtttatagg tgtacattcc tctaaacgac tgattctttt atctaaattg cgacaagcag
     3301 ttaagatact acgtgcttct tctaaaagag aaatgccaca gcgagtaaga catacccctc
     3361 gtggtagtct gtcaaataat gctgtttcag cttgttgttc aagttcagct atagcatgag
     3421 atacagcaga ttgtgtgata tgtaattttt ttgcagcacc tgtaaaagtg cctgtttgtt
     3481 caattgcttc taaaatctct aaatatcgta tgtttatcat aataaatatc ctcactagac
     3541 atgaataaaa ttgattaatt ccattaaatt ctatcatttt acagattaca aagcaacagg
     3601 tatacttaat aatatgaagt gaaaagaagg aggaatattt tgaatcaaag cagaaaaaca
     3661 tatttttggc ttttaattat taacttgttt attagcacat tcacttttgg tggagggtat
     3721 gtagttgtac ctatgattag acgttatttt gtaaatcaaa agcaattctt tacagaagat
     3781 gatttgatga gcatggcagc agttgcacaa tcaactcctg gagctattgc aattaattta
     3841 tctgctttgg caggttatcg agtagctggt actttagggg ttgtcattag ttgtatagca
     3901 gctataatac ctccacttgt tattcttgga ttagtatcag cattttacac cacttttata
     3961 tctaatgcca ttgtaactgc agtattaaaa ggaatgcaag ctggtgttgc tgcactaatt
     4021 gtggatttga ttattgacat gtgctctatg atattaaaac aacgttctct atttttatca
     4081 gctatgatac ctattgcttt ctttgcaaac tttgtgatga gtataaatgt aatttttata
     4141 ttatctgttt gctgttttgt atgtgtaatg caagttttct acaagaagag ggaaaataaa
     4201 tgaatacaat ttggaactta ttttttatat ttttaaaaat aggcttgttt agtattggtg
     4261 gtggttatgc aatcatacct ttaatccaag agaaagtagt aaatcaaact ggatggataa
     4321 gtgagaaaat gtttacagat attataacta tttcacaaat gacaccaggg ccactggctg
     4381 ttaatacttc tacttttgtt ggacttcaaa ttggagggtt ttggggagca tttgcagcca
     4441 ctttaggttg tgtattatgt ggtgtagtaa tatctctatt tttatataat ttttttcaaa
     4501 agcatcagaa ctctacttat atatttgaaa tattaaatgg tctaaaatca gcttcattag
     4561 gtttaattat ctcagctgcg gctacaatta taattcttgc attatttggg acgaataaag
     4621 tgtacttcaa ttctatattt gagatgctaa actggactgc actaataatc ttttttgtta
     4681 cactactgat agtacgtaag tggaaaatta atcctattgt gattataata ataagtggta
     4741 tactgggaat atttttttat ttataagttt ttggtaagta gaggatatct atttttttat
     4801 atcttaaatc caaatagcca ataaagtaag gttatttgga tttttaataa attctgaaaa
     4861 gataatcaga aacccataga acatttaaat tatatcactg gttttctaca aagcaatcat
     4921 aagcttcttg gcaaaatttc tcactatcta tatagtaact attatgaaca ttattaattt
     4981 caacaagttt ctttttacat tttagtgaat tataatagct atcaaaatat tgggttttaa
     5041 aatatctatc atgaagtgtt ttaaagacaa gagtaggtat gttgactcca tcttttatct
     5101 tactatcttc tgcaataaag cattctaaca ttgtattaat tatctttgta ctatttttcc
     5161 aaatatgagg atttttcttt tcaaatattt tataaaattc attatcatag acttcattat
     5221 aacctttata tttaggtggt tttactgtta tgtgaaaatt aggaagaaac ttaaagaaaa
     5281 aatataataa tttttatgtt ctgttttata tattattcat attttatcac agataatata
     5341 ctaaagttaa tttttttatt gtacaactat tataataatt cttctataat ataagacatt
     5401 ctataatttt atatttaagt tcatgtgtat ttaattgttt ttatataaaa tgtccagtaa
     5461 tactatttgg atttattttt atttcatcag gagttccaga agcaacaatt tcccctccat
     5521 ttattccact gtctggacct atatcgataa tccaatcaga agcacgtata acctctgtat
     5581 tgtgttcaat aattaaaagt gaatgctgtt catttacaag ttttctaaaa gtaatcaaca
     5641 aattttctat atctttaaaa tgaagtccag tagtaggctc atccaatatg tacagcattc
     5701 gttttttagt ttttgtccct aactcttttg ctaattttat cctttgagat tctcctccac
     5761 ttaatcctaa tgtattttgt ccaagcttta gatatccaag tcccacttca tctaataagg
     5821 agagttttct atatatatca gagcaatcac taaaaaatgt ttttgcttct gctacttcca
     5881 tgtcaagtat atctgcaatt gtctttccct tgtattgtat agacagtatt tctttttgat
     5941 atctcttacc ttgacattca ctacaagtta cccattggtc tgccatatat tgcagaataa
     6001 tttttgtttt acctaatcct tgacagtttg ggcattgacc ctttttgcta ttaaagctaa
     6061 aatagctttc atccaataat ttttgttttg cttgtggagt ttcagcaaat agagaacgaa
     6121 tttcatcaaa aatattgata tatgtagcag gtgtagaacg gctagatttt ccaataggtg
     6181 tttggtccat taagataaaa tcatcaatag catcaaatcc agtaaattca gtataatttt
     6241 tatctgggat agatttttgt ttcaattttt cttctagagc aggaagtaaa ctgtgaaata
     6301 caagagagct cttaccagaa ccactaacac ctgtaataga gcacatacag tttaagggaa
     6361 tttctacatc aatatttttt aagttatttg catggcatcc ttttaagctt aaccatttac
     6421 ttggtataat tttattttgt gaacttatct tattgtatgt acttaaatat ttacctgtta
     6481 tagagtttgg attttttata atttcttggg ttgtaccttc tgcaataatg aacccccctt
     6541 ttgtaccagc acttgggcct acatcaataa tataatcagc agacagtatt gtatctttat
     6601 cgtgttccac aactataaca gtattaccct tatctcttag ctcttctatc attttgatga
     6661 ttaaattatg gtctcttgga tgtaaaccaa tagatggttc atctaaaatg taggttaagc
     6721 ctactaattc acttcctagc tgacttgata atcgtactct ctgcagttct cctccagata
     6781 aagttggagc tgctctatct gttgatatat agctaagacc tacctttaat agataactaa
     6841 ctcgaatttt taattctgtt aagatatcat ttaccaaaga tagctcattt ttttgaagtt
     6901 gatttggtaa ttcacacaac caattccata actgttctat cgtcattttt gttagttcag
     6961 ggaagcgata acctttgatt gtagtgaatc tagcctcaat gcacagcaat tcgccaccac
     7021 atgtattgca aggaattttg ttcatatatt gatgcaaggt attattttca gaactagatt
     7081 ctctaaaaag tctttgaatg tggttgattg ctcctgaagc aggtcttcta atctttgatt
     7141 ctcgtccctt tgattcaaag ctaaattcat atatcttatc gtctgtacca tataagattg
     7201 catatataaa atctcttggt aattcattcc aaggtatatc taggtctata tttttatctt
     7261 ttgctattgc atataattca cctaccatcc aattaccatt tggctttttc cccctcaatt
     7321 ttccaaaata gtaagtagct ccatctaata ttgaaatagt tgggtctttt acaattaatt
     7381 gaggattaac ttgataggta aaacctaatc cattacaatc gtgacaagct ccagtatggg
     7441 agttagcatt gaaggttgaa gtatttatct tagaaaaaat agtttgacaa tgtggacaat
     7501 aattttttgt attattcttt ttttctaatg gaattttgca atatggacag taactttttc
     7561 cgattgatac aaataacatt cttaaataat cccaaatgct tgtaagagta ccaacagtag
     7621 agcgaggatt ttggcttcct tttttctgtt cgatagctat agtaggggtt aatccctgaa
     7681 gtaaatcaaa ttctggtttt tgaagctgct ctgaaagttt tgctccatta cctagatttt
     7741 caaaataacg tctttttcct tcttcataaa tcgtatcgaa agctaaagaa gattttccac
     7801 taccacttac acctgtaata acagttattt gattttttgg aattgtaacc tcaacatcct
     7861 ttaaattgtt ttgccttcct ccttttagat agatagagct tttattatga caaagtgaat
     7921 ttttaattga tttatttatt gcttttgcaa atttgaattt cttttctagt tcaagaggat
     7981 tgcctaattc ttttatttcc gaaataccta atatttttaa ctgagaaaag attgatttca
     8041 aataatcttc aggcaatttt tctattaaca aattaaggtc ttctattttt atatttccgc
     8101 ttgataatat ctctgccatt tcatctaata aatttttttc tgctcttgtt aattgattgt
     8161 attttttgga acttaattct gtccataaat cccatggaag caattctaaa ccaatcatat
     8221 tattaaagtc atgtagaaga ttacccttta cagaatgcca acctttccaa tttttattat
     8281 atccaaagtc atctggatga gcatgtcctt gtcgacatct tatccaggct tctgaaccag
     8341 ttaaaaaacc atctgttttt ccgacatcat gagtgtcaaa attaatttga aaataatttt
     8401 tttgtatgtc atctatttgt gcatctattc ttatccatct ctttgttaga gtatcatagt
     8461 attctacaag ccagtggtct tcataagtaa gctcactttc aaaataatta gcaaaacctg
     8521 ctctcattct agcctcaaaa cctcgatatc ttaggagcga tacaagaagt aaagaataat
     8581 ctctgcacat tccaacaagc ctttgttttg ggtttcttgg aatagttagt gggttagaat
     8641 ttatttcaaa tattcttttt aacatttgag gaactgtacg aagcaattcc tcatcagatt
     8701 gttgcttatt aaaggatata ccatataatt ttccttggtc tccatgaatt actaggcttt
     8761 gaaccacttt taataactca attggagtct ttggtaaatc ttgatattta ttttcaaatt
     8821 ttttaggatt tgtgatgatg ctttgatttt tatagttatt tattttcatt tatatttcac
     8881 ctctctaaat ggatgatata ccctgacatg gtgtcatatg caaggacaat ttagattttt
     8941 tggccaaaat ttaaaaataa ataaaaaatg atacagtgat aaattgtgat acaaatatag
     9001 tttcaaattg catataatat aattatttaa taaaaccatt atctatggaa tgttaatgaa
     9061 atgttaagat ggcattcttg aatattaaga aatagaatac tataatatag tgtgaaggat
     9121 tcttagtaaa aaaatttgta agtgttaata tacattaaaa aataggttta taatttggag
     9181 gaaaaaaatg aaattatcaa ggtataagaa aaatagttta gttctgtcta taattttatg
     9241 ttcacttatt atttcaatcc ttgtaattac tgtttttaat accgtaaaac tacacaatat
     9301 atctaataaa caatctaaaa actatttaaa cgatgtatct acacagattg taatgaatgt
     9361 tgattctaaa atcaaattta ttttatccga cttaagaata atggcagatt ttattaagca
     9421 atatgaaggt gatagtcgat atgagtattt atctaaaaga aagactagtt ataagtatta
     9481 tgatgttgga ataatagatt tagaaggtaa agctgagttt ttaagtggaa aaaagtttga
     9541 cttaaagaat actgcttcct ataaaaaagg aattgaaggt aaagaatact cagaagtaat
     9601 agagtcaatg ggttttgttc tttatagtgt acctatattt aacgataatc atgaagtgtc
     9661 tagtatttta ataggtgtat ccaataaaga aagcatggat gagattctta atatagatag
     9721 ctttaatgga gaaggaacta ttgaaattat taatagtcag ggaaaaactc ttttcatagg
     9781 aaaaaataat gagttaataa aagaccttag ctataagtat aaggattctg cagatgaacc
     9841 ttgggcacaa aagatgctta atgattttaa aaatgataaa tcaggaaata ttacaataac
     9901 ctcatcaaaa ggtgtacaat gcttattaac ttatcatcca attacaagag gtttaaatga
     9961 ttggcatttt cttctcatag tacctgaaga tgctgtactt ggtgaactta ataagttaaa
    10021 ttcttttaca ataataatga catttataac tacatgtatt attggaatta taacattaat
    10081 tttatatatt ataagaagaa aatatgtaaa tcaaatagaa aatattgcat atttagatag
    10141 tataacaaat ggtataaatt caactaagtt tagtatgcta gtcaaacctt taatttcaga
    10201 atcacctgat agtacttata tgatgatagc aatgaatata aaagatttta agctaataaa
    10261 tgattgtttc ggtagtgaaa aaggaaatat gacactaaaa catctttaca atattttgta
    10321 taaaaacatt gatgaaaatg aagaatttgt gtgccgtcat gatgcagacc ttttctattt
    10381 gcttattaag aatagaccag tgttagaagc cctggagtta ttatataaaa tagaagctga
    10441 cacaaattat tttaataaaa atagggaaaa tccatacttt ttaagactat cagtaggtat
    10501 ttacacaatt gaaaatcata atgaagattt aattacaata caagaccatg caaatacagc
    10561 aagaaaaagc tttaataaaa ctcatcaaag tgatttttct ttttatagtg atatagaaag
    10621 aaaacgatta atatctgaaa aagaaatttc aaatttaatg gaaaaagccc ttgaaaataa
    10681 agaatttttt atgtgcttac aacctaaaat tgatataaaa agtggaaaaa ttagtggagc
    10741 agagtctctt gtgcgttgga aaaattcaga aaagggcata atttatccaa gtaattttat
    10801 tcctcttttc gaaaaaagtg gatttatatg taagttagat ttatatatac tagaagaaac
    10861 atgcaaattg atttctaagt ggataaaaga aggtaaagaa gtgttgagaa tttctgttaa
    10921 tgtatcacgt caacatttga atgataaatt gtttttagaa aaatataagc atatatgcaa
    10981 taaatacaat gtaccaacat gtctgataga tttagaactt accgaatcta ttttcttaga
    11041 aaatccagaa gctatagata taatagagga tattcattct aatggattta aatgttctat
    11101 agacgatttt ggatttgggt actcatcatt agggatatta aaggatttta aagttgatat
    11161 aattaagtta gaccgttcat tctttgttag caaaaataat atagaccgtg gtaaggtagt
    11221 tattaagtct attattgaac ttagcaaaag gctaggtatg aaagtaactg ctgaaggaat
    11281 tgaagaatta gaacaagttg agttcctaaa aaatgtagga tgtgattata ttcaaggtta
    11341 tgttttttct aaaccattat taatttctga ttttgaaaat tttgcatatg aaaataataa
    11401 aattaaaaat atccattatt aaatgtacaa gataaaaaat ttaggcaagt tatataatta
    11461 aaaatataac ttgtcttttt tatttatata tttaataaaa atatatttgc agattttgta
    11521 aaaataattt tcaaatgttg taagttgtgg ctaaagcttt attgtattat tctgaatata
    11581 gaaagatagt tactgtctta gataaaaact gaaacataca taataatata aaatttgcta
    11641 tattaataac tctaattatt ttggaaggag ggaaaatatg ataagtggta gaatgttact
    11701 catcatgaat tttctaaaag gaaaaaataa gacaagttac aaggatatta gcaaacaact
    11761 tagtatagaa gaaagaaaag ttagatatga tataaataat ttaaatattg ttttgcgttc
    11821 attaaacaaa tcagtaatac aaaagatgaa caaaggtgtg ttaattattc ctgatgactt
    11881 ccaagtagta tgtataaata ataacgaata tgtattttcc ttaactgagc gagtatctat
    11941 tatgaaaatt atatcaatgt ttaaaataga taatctaaac ttagaaaaat tgagtaaaga
    12001 atttcaggtt tctagaagtt caattaaaaa tgaccttaat gttttgtcaa gtgaattaga
    12061 aagaaaccaa ataactatta cttatgataa atcttttaaa ataagtggag aagaagacct
    12121 tatatataag caaagattga acatattaaa atcgtattct tatctttttg gtaaggaaaa
    12181 atctgattta agtgtatttg agaagtattt agtgaatgta attgaaaaaa tattcaaagg
    12241 gatttatttg attgatatat ataattggtc tatgaattta ttattgcaaa tgggatggac
    12301 tttaaatgat gaatctttta catggtatgt gtcaaacatt ttccttttta catggtatat
    12361 acattcagat gaaaaacatc ctttagaatc tgcttcatta agtgagccat gttttgaaaa
    12421 taagtttgac caagaatttg aaacaattat tcaaaaaaag ttgactaagg aacaaatttt
    12481 tctgttaaag agttttgtat tttttacaaa taaatatgca agtttaaacg aggatatgga
    12541 tttgattagt acagaaatta tagttcaaga cctaatttac aatatgtcag aaatattaga
    12601 gattagcttt aaagaagata tgattcttta taaaggatta ctcaatcata ttgccccatt
    12661 gatagagaga atcaagcaga atatacagat ttatgaggaa ttacttcatg taataccaga
    12721 taaatatcaa tatgtacttg aagctactaa ggtttctatt caaaaaaaca gagttttaag
    12781 tcaaataaag aatgaaaatg aaataatact tttggcaata catttcttag gaagtataca
    12841 tagaaatgag aggaataact acaaaaatat attgttagtt tgtggatttg gatatggtgt
    12901 aattgctatg ttaaaggata gtttagtaaa tgattaccag ataaatatag tagagagtat
    12961 tccatcatat aagttacaag attataaaga atgggaaagt attgacttca ttataacaac
    13021 atcaaagata gtaatagact tgcctaaaac aattattgag ataaatccat ttttacaaga
    13081 agaggattat ttgaagtttg aagaaaaagg gataaaaaga aagaacgtct taactaatta
    13141 tatgtcaata aaaaaaaggt tggacttttt agaagaagat gctcaaaaaa gagtattaag
    13201 tattatatgt caagaacttg gatacagtga tgagagaata ttatttagac aacttaattt
    13261 aagtgattta atagggattg ataccataag gataattgat gaagatatga aatgggaaga
    13321 tgctgtaaaa attagttcaa acatacttgc taattgtgat tttgtatcag cacaatatgc
    13381 tgagaatatt atagatattt taaaaaatgt gggtttttat gctgtaaaag ataacgaatt
    13441 tgctttacta catggcaatg atagttcatt agtcaaagta agttcgataa gtttattaat
    13501 atgtaaagaa gcagttagtt ttggagataa aaaggttaaa atcatatttt gtctagcaag
    13561 cagagataaa aaagagcaaa ttcctgcaat aattaatcta actaaaatgg tttataagac
    13621 taattttatt gctatgttag aaagtgcaaa gacaaaagaa gaagcagaag ttttaattca
    13681 taaatatgag aaggaggtca ctgtatgaat aaattagtta atgtaaaatg ttcatttaaa
    13741 atacatgcta attcaaaaga agaagctatt gtatcgttag ttgatgtagt atcaaaagaa
    13801 ggatatctaa tagataaaaa tcaattttta gaagatgttt taaagagaga agaaacattg
    13861 tcaacttata ttggacatgg tataggtctt cctcatagtc aaagtgtagg tgttaaaaac
    13921 tcttgtatta caataggaaa gcttgatatt cctattgaat ggacagaaga aggagaaaaa
    13981 gtggatttaa tatttttaat atcagtaaca aaagacaatg aaaataatct tcatttaaag
    14041 attttatcaa aattagcacg tttattgatg catgaaagtt ttagaaatca aattagatgt
    14101 tcagatgaac aaactgttta taatcttata aaagaaaaaa tagaggagga agattaaaat
    14161 gagaatttta aagtttttgc aaaaacatct tatgacagca acatcttata tgattccatt
    14221 tgtggttgca ggaggaatat tatttgcttt atcagtaact ctaagtggac aagctgctgt
    14281 tcctgaaaca ggctggttgg ctaaactgaa tcaaattgga gctgctggct tggctttatt
    14341 cattcctata ttaggtggat atatagcatt tagtatggca gataaaccag gattagctcc
    14401 aggtatgata ggtgcatatt tagcaaaaga agtaaatgca ggttttatag gtggtatcat
    14461 agcaggattt atagcaggat ttgttgtttt acaattaaag aaaattaaat tagctcctac
    14521 aatgagaact ttaggttcta tatttattta tcctttgatt ggtacattga ttacaggtgg
    14581 tataattgta tttttaattg gagaacctat agcttctttt atgacatgga tgacaaactg
    14641 gttaaatgga atgtctggtg tttctaaaat tcctttaggt ggaatcttag gaggaatgat
    14701 agcctcagat atgggtggtc ctataaataa ggttgctgct acttttgccc aaactcaagt
    14761 tgacacactt ccatatttaa tgggtggagt tggcgttgca atttgtatac ctccaattgg
    14821 tttaggatta gctacattat tgtttccaaa aaaatttagc aaggaagaaa gagattcagg
    14881 taaagcttca ctattaatgg gatgtgttgg aattacagaa ggagctattc catttgcaac
    14941 atcagatcca gttagagtaa taccttgtat tatggctggg tcgattatag gaaatattat
    15001 ggctttttta ttaggatgtt taaatcatgc accctgggga ggcctgatag tattacctgt
    15061 agttgacaat aggttggggt atattgcatc agtattaact ggagcagtag ttgttgcagt
    15121 attaatgaaa ttagtaaaaa aagacgtgaa agaagatgaa gaaattgaag aagatttaga
    15181 tgaatcaatt gaattaatat ttgaagaatt ataaatataa atggaaggaa tttgtataaa
    15241 aaagtaaata taaaactata aatttaaagg agataagaat atgaaaattg tagcagtaac
    15301 atcttgtcct agtggagtag cacatactta catgtcggct gaatcacttg aattatcagc
    15361 caaaaaattt ggtatagaaa taaaggttga gactcaagga agttctggaa tagataatga
    15421 attgtcactt aaagatattg atgaagcaac ttgtgtaata ttgactaatg atgttgagat
    15481 tagaaacatg gaacgtttta agggaaagaa ggtagtaaga atgagtgtat ctgagataat
    15541 taagaaatct gatgcattaa ttaagaaaat aaaagatact tttcaataaa aattgattta
    15601 ttttacatat aactcaaaga tgtttttaaa gaaattttta ttaaaagcat ctttgaaaat
    15661 atcttaaaaa tagaataaaa ggagatatag tcatgaaaaa gttaccaata aagactgtcg
    15721 tacaaagatt actaaactta caagaagagg ggaaaagtgc aactctttta ggaattggtc
    15781 ctatgtcacc aaacttgtta caagcaagtt ttgaactagc aaaagatgat gattttcctt
    15841 taatgtttat cgcaagtaga aatcaagtag atgcagatga actaggtggc ggttatgtaa
    15901 atggttggaa tcaggaaact tttacaaaag atattaagaa ggttgccgac aaagttggat
    15961 ttgatggttt atattattta tgtagagacc atggtgggcc atggcaaaga gataaagaga
    16021 gaaatgacca tttgcctgtt gatgaagcaa tggagttagg aaaaaaatct tatttagcgg
    16081 acattgaagc aggttttgac ctattgatga ttgaccctac aaaagaccca tttgaaattg
    16141 gaaaagtaat tccactagat gtagtactag aaagaactgt agaattaatt gagtattgtg
    16201 aaaacgagag aaaaagactt aatctaccag acataggtta tgaggttggt acagaggaaa
    16261 ccaatggagg tctgacttca actgagacgt atgaaacatt tataactaga ctaaaggttg
    16321 aacttgataa tagaggtttg ccaatgccaa catttatagt tggtcaaact ggtactttaa
    16381 ctagaaagac agaacaagta ggaactttta attttagaaa tgcttatgat ttagctcaaa
    16441 tggctaagaa atatggagtt ggtttaaaag agcataatgg cgattactta gatgatgtaa
    16501 ctttattaga acatatacca tctcaaatta ttgctacaaa tgtagctcct caatatggta
    16561 ctgaagaaac tagggcatat ttaaaattag cagaagttga gtgtaaatta gaaaaagagg
    16621 gcttagttga gaaaacttct aatatcagac atgttcttct tgttaatgca attgaatgtg
    16681 gacgttggag aaaatgggta gtaggagaac aaaaaaatct aactactgaa gagatattta
    16741 aggatgaagt tttatctaat gaaatactag atattgcagg acattataca tttaataatg
    16801 atgatgttaa aaaagaaata gaagtgcttt atgataattt aagtaagaat aatattgatg
    16861 gtcaaagatt tgttgtagac catattaaac gtcctttgcg tgattatgca gaatgctata
    16921 acttaaaagg tgttactacg aggattttaa ataaataata ggacttatag tggtgagtat
    16981 tgttatacta ggtatttata gttataatta tacttaccac tattaaattt aggaggacta
    17041 atattttgat taatttaatt tttgatgtag atgatacttt atataatcaa ttaacgcctt
    17101 tttacactgc atataataaa gtgttttctt caataaagga tatttctatt gaagatttat
    17161 atatgagtag tagaaagtat agtgatgagg tatttcatat gactgaaaat ggagaaatgc
    17221 caatcaaaga aatgcatatt tataggataa tgaaagcttt tgaggagttg ggaaattcta
    17281 ttacagaaaa agatgcacaa agttttcaag atgagtatat atatcaacaa tcacaaatta
    17341 cactaatacc agaagttgag atgattttaa atttttctaa agaaagaaat attaatctag
    17401 gaattataac taatggccca tcaaaccatc aaagaatgaa gttaaagcag ttaaatattg
    17461 aaaactgggt tgataaaagt aatattttta tttctagtga ggttggattt tctaagccag
    17521 atactaatat ttttagagta gctgagaatg ttatgaattt agatagagaa aatacatatt
    17581 atgtgggtga ttcttataga aatgatgtat taggtgctaa aaaagctggt tggaagagta
    17641 tatggttgaa ccatagagga catgaggtag aagagttgtt ttataaacct gattttgtaa
    17701 ttttggaaca taaggatttg atatctttat ttataaaaat atgtagttat aaaaatatgt
    17761 agtaaaaaaa tgttaataat agaattgtat aaaataatta ataataacta tataaaatta
    17821 tatgtttaga ttgtgagcaa tctattttat gttaaaaata gattatttag aagaagggga
    17881 aatcttaaaa aaatttgaat atcccctttt tattatttaa ttaaaatgaa atagttagaa
    17941 atatatttta tttagtttag tcaataacat tttgggattc tttataacta catgttaact
    18001 gttgaatagg tttatcatat ggtttaaccc atcctttatt aatacttaat tctgtaagtg
    18061 ctgtgtgacc ttctaccatt tgagttaatg aagctgaata tatagctctt aattcaggtg
    18121 tactacttgt caatgcagaa ttaagataca tattggcaga tgctttagca gatgaaagca
    18181 tacttaacat tattacttta tcgtctatat aagtattgtt cttaattaga ttttctatca
    18241 tatttctcat gttatctata cctcctcaga aattagtatt tcattttcaa ctataaattg
    18301 ttgtatagct ttaattcttc cttctgttgc taatatacta gattctgatt gtctttttag
    18361 gtcttcatct gatattaaca tatttattgc tctttgcata agtaatccgt cagactccat
    18421 ttttataact gctgctaaag atattttttc agtttctgaa agtattctca tttaatcatc
    18481 tcctatattg taatttatgc tttaatagta tgtctttctt ttcaaggaaa taaccattac
    18541 acttttttac agtattttat attctcttta tatcaaaatt tagtcgacct aatatattaa
    18601 tataattttg taggatattt atcattaaat atctataaaa taaattattt gaatattcat
    18661 aaagcaaaat ttatttgtat gtacttcttc aagagtcaat atgagttttt tcaaaaaatt
    18721 aatttttatg ataatcatta agggctatat ttttcttaaa gttgtgatta tcattattaa
    18781 tttacaataa aattgccgaa aagccctctc ctttaggtgt agggatgaaa ggtaaggtct
    18841 taatataaaa aaagttagaa taatgcttgt aatctaatac cgctactgat accctatatt
    18901 taggaggtgt tagtttttat gtataaatct aacaaaaata tagtttatga ttgcaaatat
    18961 catattgtat tttgccctaa gtatcgtaaa cctgttttag ttggcgaagt tgaaaagatg
    19021 ttaaaagaaa tactaccata taaagcagat gaacttggag cagaaataat agaaatggaa
    19081 actgataaag aacatgtgca cttattaata tcttgtgacc ctcaatatgg aattcataaa
    19141 gtagtaaaag gtttaaaagg ctttagttcg agagtattaa gagagaactt tccacattta
    19201 aagtctagta tgcctagcat gtggactaat agctattttg taggtactgt tggttctgtg
    19261 agtttagaag tagttaaaca atatatagaa aatcaacaag ttaggacaaa gaaatgataa
    19321 aaactcatag agtgaaatta aacctaacta gaacacaatt tgaattagta agggaaaagc
    19381 aaatggaaag tgctaactgt tggaactaca tagttaactt atctaaagaa tactattttg
    19441 aacataaaca atggattaaa aagaatgata tacaaaagtt aatcaaaggt aagtacaatc
    19501 ttcatagtca aactattcaa gctatatcag ataaatttga tgcaaataga aagactatat
    19561 cagaattaag aaaaaaaggt aatactaaag caaaatatcc atacaagact aagaaatttt
    19621 atataatacc ttttaaagct agtgctatta atagaaatgc taaaggcaac ttaaaattat
    19681 caatgtcaaa aggcaggtat ttagaattag attttaatgt tgagaatata aaaactgctg
    19741 aaatagtatg gcgaaatgga tattatttat actacacttt tgacaatgaa ttaaatggag
    19801 ttgtagccaa aggcactaat accgtaggtg tagacttagg ggaaatacat tcgatagcta
    19861 gtgtaacaaa tgaaggtgta gggcttattc tatctaatag agaaggcaga agtattaaac
    19921 aatttagaaa taagatgtat gcttatatat ctaaaagatt aagtaaatgt aaaaaaggta
    19981 gtagacaatc aaagaagtta tggagattaa aaaataagat aagaagtaaa acagataatc
    20041 agttaatgaa tttatatcat caaacaacta gaaagtttat agacttttgt gtagagcaga
    20101 aggtatatga aatagttctt ggggatataa aaggggttga aaaagatact aagaaaaaga
    20161 aaagattaaa cagagttaat agacagaaaa tatctcaaat ggagtatggt cgaataaagg
    20221 actatataaa atataaagca aaagagcaag gtattgaagt taagttagtt aaagaaaact
    20281 acacttctca aacttgccca aagtgttcta aaaaacacaa accaactggt agaacttata
    20341 gttgtacttg tggttatgaa actcatagag atatagttgg tgcttggaat attttaaata
    20401 aaaagcataa atatggttta gtagatttta gaataaatca taagcaacca ataaatttaa
    20461 aagtatctac cgtttgagcc atgtgtggac gaataacttt aaggtagtag tggcgaagac
    20521 accgtccgaa gtagcttggc tttgtaacca cctctgttgt actgtttaag tataaataag
    20581 tgtgttagcc accaagaatc cccttgcttt agctatgggg agtgtgtcaa taaaatactt
    20641 taatgaaaaa tagctaactt taattgtagg atattcttaa tatatttgaa ataaataaaa
    20701 atattgaagg atataatatt caattggtat ataaataata aatgatagtt aaattttacc
    20761 ttagaggcta attaggtgtt tagtcaaagt taatgccttt agaatacaaa tgtattctaa
    20821 aggcattttt actatgtatt ttcatttata ttattaaaca ttatctattt ttatatacat
    20881 ttctatgtat tttattttca tcaaatcggt ctataaactc atttttttct tcactatatc
    20941 caatagatat aagtgcataa ggaactaatt ttaatggtaa gtctaaagtt tgtctaactt
    21001 tatttaccac tttattttta ggaaatactc ctgcccaaca agcagctaga ccttgattag
    21061 taacttctaa taataaattt tgtgtgcaag cacctaaatc ttgtatccat ttaccaggtt
    21121 ttaagaattt atctctattt ccaagcacta ctatacataa tggtgcaaat tctatatgct
    21181 ttgctctatg ctgtgacttt gagagctgtt tcagcagttc cttatcatct actataataa
    21241 attcccaagg ttgagcattt tttgatgaag gtgcttgcat agctgatttt agtatttcag
    21301 ttattttatc ttcttctata tttttatcta tatatgttct tattgaacgt ctatttttta
    21361 taacttctaa catacagatt ctcctttaaa taaaattatt tctatttata taatatcatt
    21421 actttaaatt ttagctatta cttatataaa gaataaactt tgtgttggtt ttatctaagt
    21481 aaaagtaaca ttcagaacta aaaaacaaga ctataaatcc aaagtattaa ttaaaaaaga
    21541 agtaataaaa aataatatac aagatttaaa aaagagtatt gggcttaaaa tttaattaga
    21601 aaaccaattt tgagataatc tgttttttat tttaacaaaa aaacataaat aaagttcgat
    21661 acgtagcgaa tgaaaaaatt acaagaaata ttttttttaa aaaatttcaa aaaagagttg
    21721 ataatatatg tatattaata taaaatttaa ggtgtataat tcgtataata atacgaatga
    21781 tttgtagtgt aaaataactt ataaacggag aggggaagtc taatgaaagt agcagtagtt
    21841 atgggttcaa aatcagatta tccaaaatta gaagaaggga taaaactgct tgaaaaatat
    21901 ggaatagaag ttgtagcaag agcattgtca gctcatagaa caccagaaca actttcaata
    21961 ttcctaaaag aaatagaaga tgatactgat gtaataatag cagcagcagg aaaagcagca
    22021 cacttaccag gtgtaatagc ttcacaaaca ttaattcctg taataggatt acctattaaa
    22081 tcatcaacta tggatggact agactcactt ttatcaatag ttcaaatgcc aaaaggaatc
    22141 ccagttgcaa cagttacaat agacttaggt ttaaacgcag ctttattggc attacaaata
    22201 atgactttaa aatacccaaa attaaaagag gatttgaaat catatagaga agagatggca
    22261 caaaaggtgt tagaagacga caagaattta agggggtagc agaaatgtta ttatatgaag
    22321 gaaaagcaaa acaagtatat tctacagata atgaaaatga atatgttgtt tattataaag
    22381 atgatgcaac agcatttaat ggagaaaaaa aagcagaaat atcttcaaaa ggtatactaa
    22441 ataataagat atcaacaata atctttgaaa tgttaaaaga aaataatata aatactcact
    22501 ttataaaaag tttatcagat agagaaatgt tagttaaaaa agtagagatt ttaccattag
    22561 aagtaatagt aagaaatatt gctgctggtt ctatctgtaa aagagttggt cttgaagaag
    22621 gtgtagtttt cgatgagcca atttttgaaa taagctacaa aaatgatgct tatggtgacc
    22681 caatgctaaa tgatgattat gcagtggcaa tgaagttagc aactagagaa gagttaaaat
    22741 tcttaagaga agaaacttta aaaataaacg agttactaaa agcatttttc ttaaaattaa
    22801 acctaaagtt agttgacttt aaaatagaat ttggtaaaga ttctgaagga aatataatat
    22861 tggcagatga agtatcacca gacacttgta gactttggga tgtaaataca aatgaaaagt
    22921 tagataagga cagatttaga aaagaccttg gagaccttgt agaaggttat acggaagtac
    22981 tttcaagaat gaataataaa taggaggcaa atgtatgtgt ggagttttag ggatttactc
    23041 taataaagat gtaactaaag aactatatta ttctttatat tctatgcaac acagggggca
    23101 agaaagctgt ggtttagctc ttttagatga tggagaaatt aagtacaaaa aagatatggg
    23161 attagttgga gatgttttta aggaaaatga attatctaag ttaaaaggaa atatagggat
    23221 tggacatgtt agatattcaa cagctggagg aagtcatgtt tctaactgtc aacctttagt
    23281 tggaagttgt agaaaaagac aattagccat agctcataat ggaaatctag ttaatgcaaa
    23341 ttatttaaaa gatatgctag aagaagatgg atatatgttc caaactaatt cagatacaga
    23401 agtgatttta tatatacttg ctagatatta caaaggggat atagtagaaa gtttaaaagt
    23461 gacaatggat tatataaaag gtgcatatgc tcttgtaata atgagtcaag aagaattggt
    23521 tgcagttaga gacccacatg gattcagacc tcttgtactt ggtaaaaagg gtgatgaata
    23581 tatatttgca tcagaaaatt gtgcaataga tatacttggc ggagaagtta taagagatgt
    23641 agagccagga gagataatag tagtcaaaga tggagaacta aaatcatatt tttattcaga
    23701 aaattataaa ccagttaaga aaagttgtat atttgaacac atatactttg caagaaatga
    23761 tgcaactata gacaatgtaa atgcatatga atttagaatt aaatgtggtg agagattagc
    23821 tcagaatgaa actgtaaagg cagatatggt agttccagtt ccagattcag gttggccagg
    23881 agctattggt tatgcaaatg ctagtggatt aaaaataagt gaaggcttag ttaaaaatag
    23941 atatgtagga agaacattta taaaacctac acaagaagaa agagaaatag cagtaaaaat
    24001 aaaattaaat cctctttcaa caataataaa aggaaaatct ataattttag tagacgactc
    24061 aattgtaaga ggaactacat ctaaacaatt agtaaaatct ttaagagaag caggagcaaa
    24121 agaaattcat cttagaataa cttctcctcc agtagcttac tcttgttact atggaataga
    24181 tactccaaat cgctctaaat taattgcatc aagtaacaac gtagaagaaa tgagagaata
    24241 tattggatgt gatagtttaa aattcctaga tatagaagga atgttagatg caacagaaca
    24301 taagtctact ttctgtaaag cttgttttga tggagaatac ccagttaaga aaattgataa
    24361 ggaggaacta ctttcatgtt aacatataaa gaatcaggtg tagatataga tgaaggaaat
    24421 agagcagtag accttataaa aggtaaaata aaaggaactt atgatggaaa tgtagttgga
    24481 gatttaggta acttcagtgg attatacagt ttaaaagatt ttgtaggtat gaaagaacca
    24541 gttttgcttg catctacaga tggtgttggg actaagttaa aaatagctca gatgatggac
    24601 aagcatgata ctgttggaat agatttagtt gcaatgtgcg tgaatgattt aatttgtcaa
    24661 ggagcaaaac cattattctt ccttgactat atagctcttg ggaaattagt gcctgagcat
    24721 atagaaaaaa tagttggtgg aattgcagat ggttgcaaaa tgtctggttg tgcactaatt
    24781 ggtggagaaa ctgctgaaat gcctggaatg tatggagaag atgactatga tttagcagga
    24841 ttttctgtgg gaatagcaga caaagaaaag attgtttctg gaaacaatgt taaatcagga
    24901 gatgtattgg ttggtatatc ttcaagtgga gtacacagca atggattttc ttttataaga
    24961 aagatatttt tagaaactta caattataaa atggaacaat atgttgaaga actaggaatg
    25021 acagttggag aagcactttt aacaccaact aaaatatatg ttaaattagc tttagatgta
    25081 ttagctaaac atgacataaa agctatagct cacataactg gtggagggct tatagaaaat
    25141 ataacaagag ttatacctaa aggattagga ctagatatca ataaaaaatc ttgggagaag
    25201 cctcctatat ttaaaatgat agaaggtttt aatgctgttg atgagagaga acttcataag
    25261 agttttaaca tgggtattgg gctagtttta atagtagata aagaaaatgc tgatgatgtt
    25321 gtaaacttta taaataatag agaaaatgac aatgctgatt atgtagataa aaaatatagt
    25381 gaattattag aagataaagc ttatataatt ggtgaagtag tagatagtca tgaaggtgta
    25441 gaattatgct aaatatagga gttttaatat ctggtggggg aacaaattta caagcagtta
    25501 tagatggtac tgagtctgga gaaataaaag gtcaggttaa agtagttatc tcaagtaagc
    25561 aaggtgctta tgggctagag agagctaaaa atcataacat aaaagcaatt tgtgaaactg
    25621 atgaagacaa gataatagaa attcttaagg aaaataaaat agatttagta gttttggctg
    25681 gttatttaaa aataatcagc ccaaagctgg ttaatgagtt tagaaacaaa atgataaaca
    25741 tacatccatc attaattcct tcattttgtg gagctggatt ctatggagaa aaagttcatc
    25801 aaggtgttat agattacgga gctaaagtaa ctggtgccac agttcatttt gttgatgaag
    25861 gtgctgatac tggaccaatc ataatgcaag atgtagttaa ggtaaatcaa gatgatgatg
    25921 caaagacact tgcaaaaaga gtgttagaag ttgaacatag gattttaaaa gaaagtataa
    25981 gtcttttttg tgaaaataaa ttaaaacttc aaggtaggag agtgtttata aatgagtaag
    26041 agagctttaa taagtgtaac tgacaagact ggtgtagtgg aatttgctaa agagttaaat
    26101 aaattagatt atgaaattat atctacagga aatacattta aaacattaaa agaaaatggt
    26161 gttaatgtaa tgcaagttga agatgttaca aattttccag aaatattaga tggaagagta
    26221 aaaacattaa atccatatat acatggtggt atactttata aaagagataa agaatctcat
    26281 gtagaaactg taaatgaaca caaaatacat tcaatagatt tagtagctgt aaatctatat
    26341 gattttgaag gaactttaaa agctggaaaa agtcatgatg aaataattga aaatatagat
    26401 attggtggac catctatgat acgttctgct gccaaaaact ataaggatgt aatagtagta
    26461 gtagatataa aagattatga ttctataata gaaaaattaa aaacagatac aatgacatta
    26521 gaagacagaa aaaaattatc atataaagct ttctcaacta caggaagata tgatgcgtta
    26581 atatctagtt attttgctgg agaagttgga gatacatatc ctgacatatt aaatttaact
    26641 ttccaaaaag aacaaacttt aagatatgga gaaaatccac atcaaaatgg tttcttatat
    26701 tcacagtcaa atgcaaaaaa tccaatctta aattatgagc aattaggcgg taaagaactt
    26761 tcttttaaca acttaaatga tttacatgga tgtttagaag taatgagaga atttaaagat
    26821 agtgaagaag tagtttcagt agctataaaa catgctaatt catgtggggt aggtctagga
    26881 aaagatgctt ttgaagcata tacaaaatgt tatgaagcgg ataaggtttc aatatttgga
    26941 ggaatagtag gaataacttc tactatagat aaagctacag cagagaaatt aaatgaaata
    27001 ttcttagaga tagtagtagc atatgatttt gagccagaag ctttagaggt acttaaacaa
    27061 aagaaaaatt taagaatatt aaaattagct aagatagaag atagtttaca accatatgaa
    27121 atgaaatatt tagatggaaa attattaata caagatagaa ataatatatt agcagaaaaa
    27181 agtgaaaatg taacaaaagc aaaaccaaca gatgcacaac ttaaggacat ggaatttggt
    27241 atgagagtag taaaaaatat gaaatcaaat gcaattgcga tagtaaaaaa tggtcaaact
    27301 ttagctttag gttgtggaca aacatcaaga atttgggcat taaaaaatgc tcttgaaaat
    27361 aacaaagata aagattttac aggagctgtt ttagcgtcag atgcattttt cccatttgat
    27421 gattgtgtaa cattagctca tgaatatgga atatcagcag tagttcaacc aggtggctct
    27481 ataaaggata aagattcaat agaagcttgt gataagtatg atatggttat ggtatttaca
    27541 ggaataagac acttcaaaca ctaaggagga tattatgaag atattggttg taggcggtgg
    27601 cggaagagag catgctatat gctggaaact aagcaaagaa aaaaatgtag aaaaagttta
    27661 ttgcgcgcca ggtaatgcag gaattacaaa tgtagcagaa tgtgtaaata taggtgatac
    27721 taatatagaa gaacttttaa aatttgccaa agaaaatgaa ataggtctga caatagtagg
    27781 accagaagta ccactagtta tgggaatagt agatgagttt gaaaaagaag gattaagagt
    27841 atttggacct aataaaaaat gtgctcaact tgaaggaagt aaagcttttt caaaagaatt
    27901 tatgataaaa cataacatac ctactgcaaa atataaagaa tatacaaact tagaagaagc
    27961 tatatcagaa atagatagtt ttggatatcc agtagtaata aaagcggacg gattagctgc
    28021 tggaaaaggt gttgtaatac ctgaaaatag agaagatgct atagcaactt taaaagaaat
    28081 gatgtcagat aagaagtttg gagctgctgg agataaaata gtaattgaag agtttttaaa
    28141 aggaatagaa acttcaattc tagcatttgt agacaatgat acaatagttc ctatggcaag
    28201 tgcaaaagac cataaaaaag taaacaacta tgagcaaggt ccaaacactg ggggaatggg
    28261 aactttttca cctagtgaaa tatatacaga agaattagca aataaagtaa aagagacagt
    28321 attagaaaaa actttagaag gcttcaaaaa agatggactt aattttaaag gtattttatt
    28381 tgttggtctt atgataactg aagatggaga aaaagtactt gaatataatg taagatttgg
    28441 agaccctgag acacaatctg ttttatttag attagaaaca gatttacatg agataatgga
    28501 aactatacta gataataagt taaaagatat agaaataaac tatagtgatg atgaagctgt
    28561 atgtgttatg cttacatcag gagggtatcc agacagttat gaaaaaggga aaattataac
    28621 tggtcttgaa aacttggatg atgatatagt agtattccat agtggcacta agatgcttga
    28681 tggtaattta gttaccaatg gaggaagagt aattggtata actgcaaagt caactacagt
    28741 taaggatgca gcagaaaaag tttatgaaaa cataaagaag ataaactttg aaggaatgca
    28801 ctatagaaca gacataggaa gataattttt ctaaaatgga ggataaggta tgttgaatac
    28861 tgaaaataaa gactcaatgg ttagaagagt attagttgaa aaaagagaag gttttgacct
    28921 tgaggctaaa gctttaaaaa aagacttagt agaaagttta cacatagata atatagaaaa
    28981 tttaagaata ttaaatagat atgatgtaga aggaatatca gaagaagttt atgaaaatgc
    29041 agcaaagaca atattctctg aaccaaattt agatgtagta tattatgaag aaataccaaa
    29101 attaaatgat gaaagaatat ttgcaataga atttcttcct ggtcaatacg accaaagagg
    29161 tgattgggca gctcaatgtg tacaaattgt aaatcaaggg ataagaccta ctattaatac
    29221 agcaaaagtt tatatattat caggcaaaat aactgatgaa gagttttcta aaataaaaga
    29281 ttactgtata aatccagtag atagtagaga agcatcttta gaaaaaccag aaacattaaa
    29341 aatggaaact gaaataccaa caacagttga agtattagat ggatttatag atttagatga
    29401 aaatggatta agaacatttg taagtgaaaa aggattagca atgactttag gagacttaca
    29461 acacgttcaa aaatacttta aagatacaga aaagagaaat ccaactataa cagaaataaa
    29521 agtattagat acttattggt ctgatcattg tagacatact acttttatga ctgaaataga
    29581 aaatgtaaag atagaagatg gtaagtttaa tgatatagta aaagaagcgt atcaaatgta
    29641 tcttaactca agagacaatg tatatgtgaa cagacataaa gatatatgtt taatggatat
    29701 agccactgtt gcagtaaaag aattaaagaa gaatgggaaa ttaaatgacc tagatgaaag
    29761 tgaagaaata aatgcatgta gtataaacgt agatgttgaa gttgatggta agatggaaaa
    29821 atatctagta atgtttaaaa atgaaactca caaccatcca actgaaatag aaccatttgg
    29881 tggagcagct acttgtttag gtggagctat aagagaccca ttatcaggaa gaagttatgt
    29941 ttatcaagca atgcgtgtta caggaagtgc tgacccaaga acgactttag aagatacttt
    30001 acctggaaaa cttatgcaaa gaaaaataac tacagaagct gctcatggat atagttcata
    30061 tggtaaccaa ataggtctta caactggaca agttgcagaa gtatatgatg aaaactttgt
    30121 tgcaaagaga atggaaatag gtgcagttat agcagcagta ccaaaagaga atgtagtaag
    30181 agaaagacct gaagcaggag atgtaatagt tcttcttgga ggaaaaacag gaagagatgg
    30241 ttgtggaggg gcaactggtt catctaaaga acatagtgaa gagtcaatct taacttgtag
    30301 tgcagaagtt caaaaaggag atgctcctaa cgaaagaaaa atacaaagat tctttagaaa
    30361 taaagaagtt gctcaaatga taaaaagatg taatgatttt ggagcaggtg gagtttgtgt
    30421 tgctatagga gagattgctg atagtttaga tataaactta gacttagtac ctaaaaaata
    30481 cgatggactt gatggaactg agcttgcaat ttcagagtca caagagcgta tggcagtagc
    30541 tataaaaaaa gaaaataaag ataaatttat acaattagca gtagaagaaa acttagaagc
    30601 tacacatgta gctacagtaa cagatacagg atatttaaga atgttctgga atggaaaagc
    30661 aattgtagat ataaatagag agttcttaga tacaaacgga gtaaaacaaa ctactgatgt
    30721 ccatgttact aaagtagatg aagaaaatac attctttagc tctaatgaaa tagtaaaaga
    30781 tgttaagtgt gcaagtatga aagacaagtt tacaaaagta ttatctgacc ttaatgtttg
    30841 ttctcaaaaa ggattagtag agatttttga taatacaatt ggtggtaata cagtacttat
    30901 gccatttgga ggaaagtatc aagcgactcc aacacaaggt atggttgcta agataccagt
    30961 acttggagga gaaactaata cttctacaat aatgacttat ggatataatc caaaggtagg
    31021 aaaatggagt ccattccatg gtgccttgta cgcagtagta gaatctgtgt gtaaattggt
    31081 tgctattgga ggaaattata gtacaacaag acttacattc caagagtatt ttgaaaaact
    31141 tggtaacaat ccagaaaaat ggggtaaacc attctcagca cttttaggag cattttatgc
    31201 acaaagtaaa tttgagatac ctgctatagg tggaaaagac agtatgtctg gtacatttaa
    31261 agatatcgaa gttccaccaa cattagtttc atttgctgtt gatacagtag atgcgaagaa
    31321 agtagtatct ccagaattta aaaaagcaga ctcaaaagta gtaatgttat gtgtaaacaa
    31381 ggcagaaaat gatgttgtag attttgagga attaaagaga aacttagaca aagtaagaga
    31441 acttatacat ggaaataaag ttttatcaac atatgcatta ggatttgcag gtgtaggtga
    31501 agcaataagt aaaatggctt ttggtaataa aataggattt aagtttagtg aagaagctga
    31561 aaaaacattt acagatgata aattatttga ggctagttat ggaaatatag tacttgaatt
    31621 agcaaatgat gatttatgta tgttagaagg atacaattat gttgtgcttg gaagtacaac
    31681 taaagaagct agtatattta tcaaaggcga agaacttgca ttagatgaat tatataaagc
    31741 acactgtagt actttagagc ctatattccc aactaaaaca gaagaagtaa aatcaaagat
    31801 agagactata agttatatat cacaaggaga agctaaaaaa tcatcattaa gtatagttac
    31861 tccaagagta tttataccag catttcctgg aacaaactgt gaatatgact ctgcaagagc
    31921 atttgaaaga gtaggagcta atgcaaacat aagagtattc aagaatttaa cttataaaga
    31981 catagaagat tctatagata caatagtaaa cgaaataaaa tcttctcaaa taataatgtt
    32041 accaggtgga tttagtgctg gtgatgagcc agatggttct ggtaaattta tagctactgt
    32101 atttagaaat cctagagtgc aagaagctat aaatgaattt ttaactcaaa aagatggact
    32161 aatgttaggt atctgtaatg gattccaagt attaattaaa ttaggattag ttccatatgg
    32221 agaaataaga gttccaagtg aaagtgctcc aacacttact tacaataata ttggtcgtca
    32281 tcaagctaag attgctagaa ctagaatttc atctaataaa tctccttggt tagctcaaac
    32341 taatgttgga gatattcata atatagcaat ttctcatgga gaaggtaagt ttgttgctag
    32401 tgaagatgtt atgagagaat taattgctaa tggacaagta gcaactcaat atgttgactt
    32461 taataatgaa gctacttatg atattgagtt taatccaaat ggttcattct atgctgttga
    32521 aggtataact agtgctgatg gtagagtgtt tggtaaaatg ggacattctg agagaattgg
    32581 tgaggaagta tttaagaata ttataggtga aaaagaccaa aagatatttg aatctggagt
    32641 taaatatttt agataaagct ttgatgttta attgatagct agaatatata atttagatat
    32701 ttagatttaa agagatgtaa taatatgatg ataatcattt aatattacat ctctttttta
    32761 tttatctaag aaataataag ttcaacctaa gttaaaatac aagctgtgtt ataattaatt
    32821 attaagtaaa attgaatatt tattggaggg caacataatt aatgaaaata ttaataacag
    32881 ggtctaatgg tcaattagga aaagaattgg ttaaccaatt agaagcaatc aatcaaagta
    32941 taaaccaacc aaaatatgtt atattagcta caacaagaag tgatttggac atatccaatc
    33001 agactaatgt agataatttt attttgcata ataaacctga tgtagttgta aactgtgcag
    33061 catatacaaa ggttgatgca tgtgaagata atatcgaaat tgcatacaaa ataaatgctt
    33121 taggagtgag aaatctagca atagcatcag aaaaagttaa tgctaagctt attcacatat
    33181 caactgacta tgtattcaat ggtttttcta aatatccata taaggaagac aataaaactg
    33241 aacccaattc tgtatatgga aaaagtaaac ttatgggaga aaagtttgtt gaacaattct
    33301 cacataagta ctttatattg agaacagcat ggttatatgg taatgggaat aattttgtaa
    33361 agactatgat aaaactttct ttagaaaata aagaggttaa tgtggttaat gaccagtttg
    33421 gaaccccaac aagtacagta gacttagcaa aaattataat aagaatcatg gaaacagaac
    33481 attatggagt ttatcatgct acatgtgaag gtgagtgtag ttggtatgat tttgccaaaa
    33541 agatatttga attaaaaaat atagatataa aagtaaatcc aattaagagt aacgaattta
    33601 aatgtaaggc tcaaagacca ctatattctg tattggataa ttttatgttg aagttaattg
    33661 gtttaaattc ttttagaaag tgggaagaat ccattgaaga atatttagaa agatatgata
    33721 taaatgaaaa gtaaatgtat tatttttaga aaagaaaata agatattata aaaaatataa
    33781 atatttcttt tatttatccg ataatcataa tatgacaaaa acaaatttaa ggatggaaaa
    33841 agatgaaagg aattatttta gcaggagggt ctggtacaag actatatcct ataacaaaat
    33901 gtatatcaaa acaaacactt ccaatatacg ataaaccaat gatatattac cctatgtcgg
    33961 ttcttatgtt ggcagggata caagatatat taataatatc tacaccaaga gatataaaag
    34021 catttgaaga attatttgga gatggaagtt cactagggct taaaataaca tatgcaattc
    34081 aggagaaagc aaatggaatt gcagaagcgt ttataatagg agaagaattt ataggaaatg
    34141 acagagtgtc tcttgtattg ggggataata tattttatgg atatggattt agtgaaaggt
    34201 tggagaatgc agttaaaaga aaaggagcaa ctatatttgg gtatcatgta agtaatccaa
    34261 attcgtttgg agttgtagaa tttgataagg attttaatgt attgtcaata gaagaaaaac
    34321 ctacagttcc taaatctaat tatgctatac caggattata tttttatgat aatgatgttg
    34381 tagagatagc aaagctagtt gaaccgtcag atagaggtga attagaaata acctctataa
    34441 acagtgaata tctaaaacga ggaaaactaa aagtggaact tctaggaaga ggtatggctt
    34501 ggcttgatac tggtacacat aaaggtctat tggatgcttc taattatgtt gaagtggttc
    34561 aaacaagaca gggactgtat atagcatgtt tagaagagat tgcatataca aaaggatata
    34621 taagtagaga acaattaatg aaactagcca agccactgat aaaaactgaa tatggtcaat
    34681 atctattaaa attggctagt gaagatatgc aatatggtag ataaaattta ttataaattt
    34741 tattaaggga gtttattata atgggaaaaa tcaatgttat aaagactaaa atagaaggat
    34801 tatatatagt cgaaccaaat gtattttgtg atgaaagagg atattttatg gaaagctata
    34861 ataaaaagga ttttatagag cagggtcttg atatgtgttt tattcaagat aatgaatcta
    34921 gctcaagaaa aggtgtttta agaggaatgc attttcaggt tagatatcct caaggaaaat
    34981 tagtcagagt tacagagggg gaagttttcg atgttgcagt tgatttaaga aaagattcac
    35041 aaacatttgg gaaatgggaa ggtgtaatat tgtctgataa gaataaaaaa caattttata
    35101 ttccagaagg gtttgcacat ggatttttag ttttatcaga aaaagcagta tttaattaca
    35161 aatgtacaaa ctattattac ccagaatttg agaatgggtt tatatggaat gacaagcaaa
    35221 tatctattga gtggccttta aaaggaattg aagaaatatt tttatcagaa aaggacaaaa
    35281 aacaaaaaag ttttagagat atttgtacaa gacgttaata aaaatttatt agaattaaca
    35341 tttaggagaa aaaatatgaa aaaaatactg ataactggag gggcaggatt tattgggagt
    35401 aattttatac attatatgct taacaagtat gtagattatt ttattgttaa cctagacttg
    35461 ttgacttatg ctggtaattt agagacatta atagaaatac aagacaattc caattataaa
    35521 tttgttaaag gagatatttc aaatagggag caggtgtata agttatttga agaagaaagg
    35581 tttgatatag ttgttaactt tgccgctgaa tctcatgtag ataggtcagt tgagaatcct
    35641 gatttattta ttaaaacaaa cattatagga acacaagtac ttttagatgc atctataaaa
    35701 tatggagtta aaaggtatca tcaaatatct acagatgaag tgtatggtga tttaccaatt
    35761 gatagaaagg atttattctt tacagaacaa tctcctatca atccaagttc tccatattca
    35821 gcttctaaag catcagcaga tttattggta agttcttatt atagaacata tggattgtta
    35881 acaactatat ctaggtgttc caacaattat ggtccatatc attttcctga aaaattgata
    35941 cctcttatga ttttaaatgc tttggaaaac aaacaattgc cagtatatgg caatggggaa
    36001 aatgtaagag attggttaca tgtatatgac cattgtactg ctatagactt aataatacat
    36061 aaaggaaata taggggaggt ttacaatata ggaggtcata atgaaagaag taatctagaa
    36121 gtagtaaaaa tgatattaaa tcttttaggt aaatctgaag agttaatatc ctatgtaaat
    36181 gatagacctg gtcatgattt aagatatgct attgatgcaa ctaaaataga gaatgagtta
    36241 ggttggaagg caaaatatga ctttgatttg ggtataaaag aaactgttaa gtggtatata
    36301 gaaaatgaat cttggtggaa agctgtttta tcagtataac tttaaaattt agaaaggggc
    36361 gttttatatt gaatgagata agttcactaa ttaatatatt agcattgact caattatctg
    36421 gtagtaatac tacaaatcaa tgtaattgta catataataa ttcatctgga tttgatatga
    36481 ttatgatgac cttgttaaaa gcattatcac aaaataatca acatacttct aatagctaca
    36541 atttattgtc taattctgag aatttattta atgaacttga taatgtagta aataatacca
    36601 ctagtagatt tatagatgtt gatacaaaag ataaaaatgt aaagttgaga attgaaaatg
    36661 ctgtagagca agcatcaaaa aaatataacg tagattcaaa tcttataaaa gcaataatta
    36721 aagttgaatc agattttaat ccaaataccg tttcttctgc tggtgctaag ggtcttatgc
    36781 aacttatgcc agaaaactgc agagacttag gggttacaga cccttttaat atagaacaga
    36841 atatagatgc tggaactaga catattaagg aatacattga tatgtttgga gggagcatag
    36901 aaatgggatt gatggcatat aatggtggtc ctggaagaat gaaaagtaga ggagtagaat
    36961 caatctctga cctgtataaa atgccaaaag aaacacaaaa ttatattcct aaggttatga
    37021 aatattatag agggtaggct ttattatggg gataaatata gataagctaa acataagtcc
    37081 aagtataaat atggaggtta aaaaactaaa agagagtaat aaattttctg acaaattaaa
    37141 ctctttaaaa caatcttctt cattggaaga tataaaacga aatttggaaa gtgtaaaaaa
    37201 ggcaggagaa aggcttgtac ttactcaaaa ctatggcgac attagtatat ataaaaatgc
    37261 agtaaaagaa tacctaaaat ctgttgtaga taatatgtat tcacttgata aaaatagtag
    37321 cttttgggag catcagtatt ataagaatgt aaagattgtt gatagtaaac ttgaggatat
    37381 gactagtaag ttaattagtg aagaaaaaga aaacatagat attgtttcta ctgttgatat
    37441 gatacaaggc ttgttgatag atatgtatag ataaggttat acaaggagaa aagttttatg
    37501 aatagtaaaa aagaggatat atatgaattg aattttgggc aattaataga agaaaaatct
    37561 ggtgttatag aagaaaatca aaatgttttt aatgcaaaag taaatgtagc tgtttctata
    37621 ggaaatacaa cagaaacaat aaaaaatata ttagatttaa aagaaggctc tataataaaa
    37681 ctaagtaaga atgtggatga aaaattagat atatatgcaa atgatagatt gtttgcttat
    37741 ggagaaagca ttattacaaa tgagaagtta tctgtaagat tatctaaaat agaagattca
    37801 gatgtaaatt agtattttaa atagtatccc tttaggctat gctgtatgag tttagctaag
    37861 gggatatttt tataaaaaat ttaaaatatg cgtgaattat ataaatgttt ttattttatg
    37921 agcgataact aaattataag tatgtaattt tggaggtgaa actatggata ttaaaaatgt
    37981 aagttcaaat attgtagtga ataattattt aaagaataca tctggtgtaa aaaaagtgga
    38041 agaggttaaa aaaattaata aaacagacaa gatagagcta tctaaatttg caaaggaaat
    38101 ggcaagtgtg tcaaatatga gtgatgagaa tattagaaat aaaaaagtcg atgaaataaa
    38161 aaatgcatta gaaaatggaa cttacaaaat aaaaccaaaa gaaattgcaa aaaaaatgat
    38221 agaggatatg cgaggataaa gtcatgatta cagacttaaa agttataata tatgaagaaa
    38281 aaaatataat tagtaagatg atggaattat taaaagaaca atttgattat atagttgaaa
    38341 aagacttaga aaatttaaat atgttaaatc ctaaactaga agatattagc agggagcttg
    38401 catccataga aataaagaga agacaacttt ttggtgatga tatttcaatg agtgaagttg
    38461 ttgaaaatag taatgatgga tatttaaaag aaatatatac agacttgaaa cacattcttg
    38521 ctttagctaa aaatcaacaa gaatcaaatg attctctaat aaagaaagaa cttattttta
    38581 cgaaaaaaat gattaatttc ataaaaccag ctgataagca aactacaact tataattctt
    38641 atggaaatat tagaaaataa atattaggag gagaaatatg gcaggattat tttccatttt
    38701 aaatacagct aattcaggaa tgaatgcgca ccaaaaagca atacagacaa tttctcataa
    38761 tataagtaat ctagatacag atggttattc taggcaaagg accgagtttg ctacaaatag
    38821 tccaatgtat atgcctagtt tgagtaattc aattgcaaga ggacaattag ggactggagt
    38881 acatgtaaca gatgtaacaa gagctagaaa tagtttttat gattaccaat ttagggcaga
    38941 agctcataag tatggtaata cagtttcaaa atatgattat tacaatacta tagaaactat
    39001 actaaatgaa ccatcagact atggaatatc tgcaggtata gatgattttt ttaaaggatg
    39061 ggagtcatta tcaaaggata taaatagtga cagtaaaaaa agtctagtgg tagaaaacgc
    39121 atctaattta gcaactttaa taagtgaaag ttataagaag cttgataagt taaaagaaga
    39181 tatagattct aatatagaca ctgagataaa acaaataaat gacatgttaa aaagtcttga
    39241 agatttaaat aaatctattg atattatatc tggttctggc tctacaccaa atgatttgct
    39301 tgatgaaaga gatagaattt tagataactt gagttttaaa ctagactttg aaaatagtga
    39361 tgttaaaaat atacttgcag atggtaaatt agaacttaat gaattaaaaa atccagatgg
    39421 aacttggaaa acaggtgtat cagggacctt acaaggcttg tttgaaatgc atggtaagat
    39481 tgatacatat aaaagcgatt taaaagatgt atctgatgga ttagctaaac agataaatga
    39541 tgtttataat acgtctgctg gaataacagt aacagatttt tttataactt caaatgtaga
    39601 tggtgaagat atcataaaga taaatccagc tataaagagt aacccaaatg aattaaagct
    39661 tactgctgat gaagcttcaa aaattgctaa gttaaaggat gaaaaaatag atattggagt
    39721 ggctggtgga aaagtaagta caataagtga ccactataaa gcctttgcag aatcaatagg
    39781 tttagattct caaaaagtga atcaagatga agcaaatcaa cgtaaaatta taaataatat
    39841 tgataactca cgaatgagtg tttcaggtgt atctttggat gaagaaatga cagagcttat
    39901 aaaaatacaa cgttcatatc aagctagtgc aaaagttatg tcaacagctg tgcaactatt
    39961 ggatgttgta ataaatggaa taatttaata gaagggggaa tttataatga gagtcagtac
    40021 aggtatgatg tctagcagct atctaaactc actacaagat aatctacaaa gattggataa
    40081 ggttaataga caagttaata caacgaaaga aataaacaag ctatcagata atccatataa
    40141 agcaataaag atattaaact caaaaagtga aataaagact atggagactt atgttgagaa
    40201 ttgtaaagat acagggaatt ggttagaaac tactgatact gcattagatc agcttggaaa
    40261 attattatca gacataaaga aaactttggt ggcaagtggt gatggtgcat actcagatga
    40321 tgaattaaag actcttagta atgaaaccaa tgaaaaaatg aaagaaattg caaatgcttt
    40381 aaatgcaaca catgaaggga agtacatatt ttcaggttca aatacggggg taccacctgt
    40441 tgaatgtata gataatgctg atggttcagt gagtttaaag tttaattcta gtctaaatct
    40501 taataaatta aatgactctt tgagtatgga tatagctcaa ggaataagtg tagattataa
    40561 cgttaaattg agtagccttg gatttgaccc aacaaaaact gacccatttg aagagttaaa
    40621 taacatatca aaaaaattag caaatccaga tgctgatgct ataaaagagc ttacaacaac
    40681 ttgtttgggc gatatggaac aactaataga aaatacagta aatgttaggt ctatatatgg
    40741 gacaaaagca aatacagtag aggctatgaa ggaaaaaaac gatgatagtt tgatacagtt
    40801 aaaggatatt ttgtcacaaa atgaagaaat agattatggt gaaaaacttg ttcaattaaa
    40861 ggcagcagag ttaacttatc aagcttcact acaaacagga ggaaagttat ttaatgtatc
    40921 tatattagat tacatatagt aaaataacgc agatatgatg aaggttacat taaaaaaagg
    40981 tatattaggt tttgaagatt taaaagaata tgagctttta gatatagaag ataatgattc
    41041 tttaaaagaa tttaattcta ctgaagaaga aggtatagga tttgttgttg tatctccatt
    41101 tgagattatc aatgaatatg aaatagtttt aaatcaggaa acaatagaaa aactagaagt
    41161 gaaatctcca aaggatgttg tactatttaa tataattact cttggtcaga catttgaaga
    41221 atcaactgtg aacatgaaag ctcctatagt gataaatata aaaactaatt ttggaatgca
    41281 aataatttta caggatgata aatattcaat aaggcatcca ttattgagag gtgataatgg
    41341 atgctagtaa tttcaagaaa aaaagatgaa gcagtactta taggagaaag catagaagta
    41401 aaaattgtag gggtagatgg aaacaatgtg aaactagcta tatcggcacc taacaatata
    41461 agtatattaa gaaaagaaat atacgaaaaa gtaaagagtg agaatataaa agctacaaat
    41521 aaaaatataa aaattttaaa gtcattaaaa taataagctt ggaggaagta atatatgtat
    41581 ggagaaaatc cttataattc ttataaacaa aatgctgttt ttatggcatc aaaggaacaa
    41641 ttgttactta tgcttgttga tggagcagta aaatatacca aaatagccag agcagctatc
    41701 ttagataaaa atacacagaa agcgcataga gaacttgtaa gagttcagga tatatttaca
    41761 gaactaatgg ttacattaga ccaaaatgca ggacaatggg caaaggatat gtacaaagtt
    41821 tatgattttg taagatatga actttcaaga gccaatatta gaaaagacat ccaggtaata
    41881 gataatgtgt tgcctgtaat agaacaaatt aaagatacat ggcatgaagc tgataaaaaa
    41941 agtaaagaag aaagaagtag gtacaaataa tggaattaaa tttagctgaa ttagataagt
    42001 tatcaaaaga ggaattacta ttgatgcttg tagatggtac agtaaaatat accaatatat
    42061 ccaaagatgc tcttttaaat aacgactatt tgaaagcaca taatgaactt gtaagagttc
    42121 aaaatatatt tacagaacta atgactacat tagaccaaga tgcagggcaa tgggcaaagg
    42181 atatgtataa agtttatgaa tttataaaat ctgaattagc aatagctgat gaaaataaag
    42241 atattaaaat aattgatgat atattgccaa tagtaaaaca aattagagat acatggcatg
    42301 aagtttacaa tcaactaaaa atataattag atggagggat aaaggtatgt caagtataag
    42361 tcctataaga gttacaggtc tttcaggaaa ttttgatatg gaaggcataa tcgaagctag
    42421 tatgattaga gacaaggaga aagttgataa agcaaaacaa gaacaacaaa tcgttaaatg
    42481 gaaacaagaa atatatagaa atgttataca agaatcaaaa gatctttatg ataaatatct
    42541 aagcgtaaat tctcctaata gtatagtaag tgaaaaagca tactcttcta caagaataac
    42601 cagctctgat gaaagtatta tagtagcaaa aggctcagct ggtgcagaaa aaataaatta
    42661 tcaatttgca gtttctcaaa tggctgaacc agcaaaattt actattaaac taaattcaag
    42721 tgaacctatt gttcgacagt tccctccaaa tgctagtgga gctagttctt taactatagg
    42781 agatgtaaat ataccaatat ctgaacaaga tactacaagt actattgtaa gtaagataaa
    42841 ctcgctttgc gcagataatg atataaaggc ttcttatagt gagatgacag gtgaattgat
    42901 tatttcaaga aaacagactg gttcgtcatc agacattaat ttaaaagtaa ttggaaatga
    42961 taatttagct cagcaaattg ctaatgataa tggtgtcaca tttacaaatg atgctagtgg
    43021 aaacaaagtg gcaagtgtat atggaaagaa tctagaagct gatgtaactg atgaacatgg
    43081 aagagtaact catataagta aagaacaaaa ttcatttaat atagataata ttgactataa
    43141 tgtaaattca aaaggaactg caaagttgac ttctgtaact gatactgaag aagctgttaa
    43201 aaatatgcaa gcatttgtgg atgattataa taaactgatg gacaaggtct atggtttagt
    43261 tactactaaa aaaccaaaag attatccacc tcttacagat gcccaaaaag aagatatgac
    43321 aactgaagaa atagaaaaat gggaaaagaa agctaaagaa ggtatactta gaaatgatga
    43381 tgagttaaga ggttttgttg aagatattca gtctgcattt tttggggatg gaaaaaatat
    43441 tatcgcatta agaaaactag gtatcaatga aagtgaaaat tacaataaaa aaggtcaaat
    43501 atcatttaat gcagatactt tttcaaaggc tcttatagat gatagtgata aggtatacaa
    43561 aacactagca ggttattctt cgaattatga tgataaggga atgtttgaaa agctaaaaga
    43621 tattgtatat gaatattctg gaagttcaac ttctaaactt cctaaaaaag caggtataga
    43681 aaaaactgct tctgctagtg aaaatgtata ttcaaaacaa attgcagagc aagaaagaaa
    43741 tataagcagg ttagttgaaa aaatgaatga taaagagaaa agactttatg ctaaatattc
    43801 agccttagaa tctttgttga atcagtattc ttcccaaatg aattatttct cacaagcaca
    43861 gggtaattaa ttatggataa attaaaagaa aaattaaatt tatataaaga tatatcttta
    43921 caaattataa atttgattga aaaggaagaa tatataaaga taagtagtaa gttaggtgaa
    43981 agacaagaga ttataaatag tgtaagtgaa attgatagaa atgattttat acagctttat
    44041 aatagaatgg aattaattga aattgatagt aggataagag atattttaca agggcaatta
    44101 ttagagataa aaaaagaatt acatgagtat aagcttacta aacaagtgaa cacaatgtat
    44161 tataacttaa atagagaaaa agtaaatatt tttaataaaa aagtataaag ttatgtacca
    44221 tcttgtccga ttatataaat gaagaattaa taaaaaagat taaaagtaga aatgacaagg
    44281 atgtcaacta tactaaggag ggtaaaataa tgagagttaa tacaaatgta agtgctttga
    44341 tagcaaataa ccaaatggga agaaacgtaa atgcacaaag taagtctatg gagaagctat
    44401 cttctggtgt tagaattaag agagctgctg acgatgctgc tgggcttgct atatctgaga
    44461 aaatgagagc tcaaataaaa ggtttagacc aagcaggaag aaacgttcaa gacggtatat
    44521 ctgttgtaca aacagcagaa ggtgcattag aagaaactgg taacatacta caaagaatga
    44581 gaactttatc agtacaatct tcaaatgaaa ctaatactgc tgaagaaaga caaaagatag
    44641 ctgatgagtt actacaatta aaagatgaag ttgaaagaat atcaagctca attgagttta
    44701 atggtaagaa attacttgat ggaagttcta cagaaataag attacaagtt ggagctaatt
    44761 ttggaacaaa tgttgcagga acaactaaca acaacaatga aataaaaatt gctctagtaa
    44821 atacttcaag tataatgagt aaagcaggta taacaagttc tacaatagca agcttaaatg
    44881 cagatggagc ttctggaaca gatgcagcta aacaaatggt atctagctta gatgtagctc
    44941 ttaaagaatt aaatacatca agagcaaaat taggggcaca acaaaataga ctagaatcaa
    45001 ctcaaaacaa cttaaataat actatagaaa atgttacagc agctgaatca agaataagag
    45061 atacagatgt tgcttcagaa atggttaact tatctaaaat gaatatatta gttcaagcat
    45121 cacagtcaat gcttgctcaa gctaatcagc aaccacaagg agttttacaa ttattaggat
    45181 aaaataattt tgtatattgg atatagaaga aagggtaagg ctttgcttta ctcctttctt
    45241 tttttacaaa tatacttttg aaaggaaaat atatatgtta cttagtatag ttatgattgt
    45301 taaaaatgaa gaaaaaatac ttgaaaaaac tttaaaatca ttaaccacat taagaagttc
    45361 tatagagagt gaacttataa tagttgatac aggttctaca gatgatacta taaaaatatc
    45421 taagaagtac acggaaaaag tgtattttca taattggaat aatgattttt ctagtatgag
    45481 aaatatatca atatcctatg ctaaaggtga atggttactt atattagatg cagatgaaat
    45541 actaattgat tcttcaacta ttgtgaaatt ttttaaagat ggtcttgata aaaaatttaa
    45601 ttcggcctca atacaattaa aaaatcttta ctcatatgat aaaaaattat atggatattg
    45661 ctcagtgctt agacttttta aaaacgtcga ttttagatac catggtaaag tacatgaaca
    45721 accaatatac aaaaacccta tatttaataa tgttgctgat tttgaacatt atggatattt
    45781 gtttgaagat gaagaaataa gattaaataa agtaaaaaga aatgaaaaac tgttatttga
    45841 agagttaaaa gagaatgata attctccata tacaaattat caattaggga aaaattttat
    45901 tatattagga aaatatcatg aggctttata ctatcttgag aaatcttatg aattatattc
    45961 taaactagaa tcggcacctg gttacttgat aacaagcctt gtaaaaacat atttatattt
    46021 aggaaaacat aagaagtgtg aaagattgtg cttaaagtat attaagaaag acatgaataa
    46081 tattgatata tattattata ttgcacaagc acaagtagat ttagggaagt atgaaaatag
    46141 tatagattcg tataagagat atatttactt gttagataat tatgaaataa gtacacaagc
    46201 aaatagtttg ttttcagaca ctgatactgt agggcttaag gatgaggcta ttattacact
    46261 gataaagatt tattataagc ttgaaaaata tgagtctgta atttcagagt ataataacat
    46321 tgaagatatg gaaaagaaaa agaatgtgta ctttagctta tttatgtccc tatataaatt
    46381 gaatagattt gaagatataa aaaattatta taaagaagtt tcaaattcta aaattgaaaa
    46441 aaatagtttt tatagaaata tagaagaagt tataaataat attaaagagg atgaaaaaga
    46501 gtatgtatat aaaatccttt gtgacattga aggtaattat ggtattttaa atcaaataag
    46561 gataaataaa tgtgtatcta tagataaatg taaagaaata ctcaatgaag aaaaggaaat
    46621 aatttatgca tatattataa aaatagcttt tgaagagaag attgatttac tagatatttt
    46681 ttatgaaatg gaatatgtat ggatagagaa atatctaaaa tatcttttag cattagaaag
    46741 aagttttaat ttagtactat ataagtacat aattagtcgt ccaaatacat cagatatgga
    46801 aaagataaga gtatataaag ctatatctaa agtagtttta gaaagtataa gcttaagtga
    46861 tgaaaaatat aaagagattt tttatcttta tataatgtat tcttataagt acataagata
    46921 catatataac aatttaagtg attttgaatt aataaaattt gtttgcaatg atttagataa
    46981 gttcactata gagtttaagc atctacttga cattaaaaat aaagtaaatg atgctaatga
    47041 aaaattagag tatatacata gtatgaggaa attactaaat gagtatcctt tttataataa
    47101 aataataaaa atacttatag gtgaattaga agaaaatata aaagaaagtg aagaatttaa
    47161 ggatttaaaa gatagtttta ttattagtat agaaaatatg attgaaactg gcaaaataaa
    47221 tgatgcgaaa ttattggtag atgactattc aaaaacattt gtggatgatg taaagatttt
    47281 aaatataaag ggaattttat atatgtttga aaataagctt gataaagctg actttatgtt
    47341 aaaaaaggca ttatcattag atgtagaaaa tgaagatact atatataata tagaatactt
    47401 aaaaagttta agataagtca aaaataggag aattgaagaa tgaatacacc aatagtggtt
    47461 aatgaaaaat ctaaagatat aataaaagat tggcaatata aatgtacaaa tgaagatata
    47521 aaatttacaa gcataataat attgacatat aatcaaatag aatatactaa attatgtatt
    47581 gaaagtatta ggaagtttac cccaaagaat aaatatgaaa taataataat tgacaataac
    47641 tcttctgatg gaacagttga gtggttaaag ggacaatctg atataaaatc tgtgtataat
    47701 aacaaaaact taggatttcc aaaaggatgc aatcaaggta ttgagttggc tactggtgaa
    47761 aacatattgt tgttaaataa tgatgtaata gttactccaa attggcttta taatttgaat
    47821 aaagctttat ggtctcaaga taatataggt gctgtaggac ctattacaaa tgcatgttcg
    47881 tactatcaac aaattgatgt tgattataaa tcaattgacg acatgtttat gtttgcacac
    47941 aaaataaata aatctaatat taacctatgg aaatatagat taaagttagt tggattttgc
    48001 atgttaataa aaaaatctgt gttggataat gtaggagttt tagatgaatt attcacacct
    48061 ggaaattttg aagatgatga tttatctttt aggatgatag agtcaggata taagttatta
    48121 ttatgccaag atacttttat acaccatttt ggaagtatgt cttttaaaga aaatcgtaat
    48181 aaatatatag atataatgta tattaataga agaaaatttg aaactaagtg gggatttaat
    48241 ccagaatata gtggaatgat aagaacagat ttgatttcta aaatagatga tagtttggaa
    48301 gaaaatatta atgttttaga aataggatgc ggtatagggg ctactctttt agaaataaaa
    48361 aatatatata aaaatgcatc aacatatgga atagaaatta gtgagtcagc aggtaaactt
    48421 gcaaagtata gtgcagatgt acttatagca gatatagaaa aagtaaagtt ggattatgaa
    48481 aaagattttt ttgattatat aatattggga gatgtacttg aacatttaac tgacccatgg
    48541 aagatagtca atgaactgaa acaatatcta aagaaggatg gttgtttgat atctagtata
    48601 ccaaatatta tgcatgtttc tgttttaaga aaccttgtgt taggtaattt tacatatgaa
    48661 gattcaggaa ttttagacaa gactcattta aggtttttta cattaaatga gataacaaaa
    48721 atgtttaatg atagtaatta cataataaat agtgttacag ctactagtat gccactttcg
    48781 gaaattgata atagattcat tgatacaatg tgtaaggaaa gctgtaaaga aatgagacaa
    48841 cagtacgaat cttatcaata tatagtaaaa gccactaaaa gcatagatac taaaagatat
    48901 tctagtatta gtatgattaa tttaaaatac gctttaatga gaattgataa tgaattagat
    48961 gtagatagta atttaagtta tatatttgat aattataata taactgaacc atgttttgtt
    49021 gatgatattg aatatttagt tgatacgttt gtgataaata aagcaactct attaaataga
    49081 ttaggagttg aggcatttaa cagaggttta ggagatttta gtataaacat gtttatgaca
    49141 gtattagaga tggatagaga tgatattgat tcaatatata atataacaag tgtattatgt
    49201 gaattagaag aatttgatac tgcttacaat ttaattaaaa atagtagcga aaaagtacag
    49261 gttgaaagtg acatacaaga gatactttgt tttattgagg ggaagagata tgaataatga
    49321 taagatatgt tttataacct gtgtaaatga tgaaaggctt tatgaagaat gtcttgtata
    49381 tataaatagc ctagacattc ctaaaaactt tagcatagaa acagtggctt taagaggagc
    49441 cgattctatt gcctctgctt ataataaagc tatgagagaa acagattcta agtataaggt
    49501 atacttacat caagacactt ttataattaa taaaaatttc atatatgata ttttagagat
    49561 atttaaaaaa aatacagatg taggaatgat tggtgtagct ggagtaaaag atatacctgt
    49621 gaatggaatt tggtgggatt ctgataaaaa agtagggaaa gtatatgata gtcatacagg
    49681 taaaatggat atttatgaat ttagtaactt tgaagaacgt tttaatgaag ttatggctat
    49741 agatggatta attatgatta ctcaatatga tgtattctgg agagaggata agtttgatgg
    49801 gtggcatttt tatgatttgt cacagagtat ggagtttaga caaaataaat acaaagttat
    49861 tgtaccaaaa caaaataagc cttggtgtat gcatgattct ggagtagcaa atataaataa
    49921 tggctatgat gaatatagga taaaatttgt aaaagagtac ataaatcttg atttatatag
    49981 agaaaatttt tatgaatttg ataagaagaa agcaagtacc atacttaaga gtaataagca
    50041 tgtaatggat tgtatgaaag aggagcttac agaacaatta agattaaaga attataagaa
    50101 tgttttagat attgtttcta aaattgctca tttttctgtt tttaatcata ctggcttgta
    50161 ttcttgtgaa aaatgtgaga gagcattgct agaatgtgca aataatttac cggaaataga
    50221 aaatacgaaa ttatttacaa aaaaagattt aaaaagaaga aaagtattac atgttttaag
    50281 tgaaggatat tcaacaggag gtcatacaag actagtcaaa aattggattg agattgacaa
    50341 agactctgtt cattcagttg taactacatg gcaatcagat acactgccag actggttatt
    50401 aaaagcaata gatgatagtg gtggcgaaat tatatctttg gatttaattt cagatgatta
    50461 tttaaaaaga gctatggctt tgaggaaaat agcttatgac tgggctgata tagttatttt
    50521 atatgttcat atgtgggata caatacctgt tgttgctttt ggagttgatg gggaaatacc
    50581 tattttacat gttaatcact atgacagtac tttttggtta gggacaagta ttgcagatat
    50641 tgttattgat tttagcgaag ctagtcaatt aattacatta gataaaagag gcatagataa
    50701 atctgaaata ttaccaatgc cattaaaaga aaaagaagta ttttcaaaat ctgaagttag
    50761 aaaacgatat aatttggagg aggatgtgac aataatattg actattgcta gtgaaagaaa
    50821 atacaatagt gtaaatgata ttaattactt taaaattgtt aaaacattga ttgaaaatac
    50881 agataataca attattattg ttgtaggagt tgatacagag aatctctatt ggaaaactct
    50941 aagtaacgtt acagataata gagttatatg ttttggaaca acaacaaata tagacgattt
    51001 ttacaagatt tcagatatat atatggagtc tttcatggta ggaagtcata cttcaaaatt
    51061 agatgcaatt ttatatgatt taattcctgt taaatttaaa aatgaagttt caccaatttt
    51121 tacaaatatg tggaatttta tagataagtt tgattataag aatataaaag aggttataga
    51181 tatgataaaa aggtacaata ctagtgaatt tgacagggat aagataaaag aaaaacaatc
    51241 ggaaataaaa cattttgtta tagataaaca ctgtattgaa ataaaaaact atatagacaa
    51301 aatatataat gaagctaatc atcataaagt taagtatgat ttatataaaa atgatgaaat
    51361 cgaggactat cagctttttg tagcattgta tggctatatg gtaaaaaata aaaacatgtc
    51421 ataggtgata aaatgaacaa tattcatatt aataaatttg aaaaaagctg tgaaaaaaat
    51481 tgggattatt ttgtagaaaa taaatctata aatggtacat ttctgcaaac tagaaatttc
    51541 cttaattatc atgaagaagg aaaattcact gaccactcat taataatata taaaggtgaa
    51601 gaaatactag cagtcgtacc tgcatgtgaa acttatgaaa atggtgaaag agtatttttt
    51661 tctcatttag gaagcacttt tggaggtatt ataataagaa gtggttttaa tgatattagg
    51721 catgtaaatg ctattacaaa taagttagaa acatatttac aggaacaaag tttcaataaa
    51781 gtatatttaa aaaatacatc aagaatattt tgtaaagagg atacttcatt actagaatat
    51841 tttctattta agaataatta catgttttat gatgaattaa gtatgttttt agaattaagt
    51901 aagtataaaa aagatatatt agctaatttt agatatagta aaagaagata ttttaaatat
    51961 tctttgaaga ataatcttac ctttaaaaga ttgtatagtg atgaggatat agtttgtttt
    52021 tttaatttac tttctaattg tttagatagt aaaggagcta aagtaataca ttcagtagaa
    52081 gaacttttgg agtttaaaaa taatagatta aaagatattg tagaatttta tgcagtatat
    52141 attgatgaca ttatgatttg tgggagcatg gtatttaact ttcaagaaag agtttatcat
    52201 actcaatatc tagcatcaaa ttcgacatat aataaatatt atccaatgat atttttatac
    52261 tataatctaa taaaagatgc tttagagaga aattttaagt atctttcttt tggaattagc
    52321 actctaaata gaggcaaata cttagacgag ggtttagcta catttaaaga aggttttggt
    52381 tcaagtgcaa tttgcaacag aacatactat aaaaatataa ataagtgata atcatgtttt
    52441 atagagtttt tagagtatag taaatatcta gtactctaat attacataaa aataattagt
    52501 ttataaagaa ggtttgtata tgaaaagatt aatgatttta ggctcaatta agtattttga
    52561 gaatattgtt atatcagcta aaaaagaggg aatatacaca attgtttgtg ataatagaat
    52621 tgatactcct gcgaaaaaga tttgtgatga agcaatagat gttgatgtat ttgattttga
    52681 taaaataaaa agtatagcta tagataaaaa gatagatgga attttaactg gatttacaga
    52741 ttctttaatg aaaccatatg tttatattgc aaatgaacta aatttaccat gtgtgatttc
    52801 ttgcaatcaa cttgaatctg taactaataa ggctattatg aaaaaatatt ttaaaaataa
    52861 tgcaatacct acaactgatt attgtattat tgaaagtcta aaagatttag aaaaaataca
    52921 aggattaaat tttccacttg taataaaacc tgttgatggt tatggttcaa gaggtgtata
    52981 ttttgtatca aatataaaag aattaataga aaaatttgaa tattctaagg aagcctcaca
    53041 agatggacaa gtaataattg aggaatttta tgaaagtgag gaaatacaag gactagcttg
    53101 ggttcataat ggagagtcac atgtatttta tattggagat agagagcttg taaatataca
    53161 tacaggaaga gctggaaaac cagatagatt actttatcca tcaaagtatt gttttcaata
    53221 tgaggaagaa ataaaatcta tatatcaaaa tataacacag gcttttgata taaaaaatgg
    53281 acctctttat gtacaaatgt tagtgggagc atatggaata aaggtatctg aagtaatgcc
    53341 aagattacct ggaggttgtg actatatggc tatttctcaa ataacagatt tagacatagg
    53401 aagtttattt gcaaacttta gtgtgaataa tgaagtaaat tttgatgaaa taaagaaata
    53461 taatatgcat ttatcaaaat gtgtatatgc attaccaata tacataagac ctggaacaat
    53521 aaaaaagata aataatgtag ataaaataga aaacttagat tatgtcactc aatttctatt
    53581 attagtaaaa gaaggagata caataggatt atatgaggat gagagacagg attgtggaag
    53641 agtttatgga atagcaaata atatatttga tgcaaatata aagaagaaat gtattcatga
    53701 aatgatagaa atatttgatg aaaataatga aaatatgata gaaaattttt aaataaggga
    53761 gtatgataga tatgaagcta ataactcatg aacaaattat gtcattaaac atttctcaga
    53821 aacaaggata tgaatggata aaagaatctt ttttaacaaa aaaagattgt caattaccac
    53881 caaaaataag catggtagaa gaaggtcatg tattttacaa tgtaatgccg tccttaaatc
    53941 ataaccatat gattggtgga ataaaaatgg ttacaagatt gccagggaga aatccaagtt
    54001 taaattcaga tatatttcta tacaatatga aagatgctaa attaaaggct attttggatg
    54061 gtaattatat tacagctttt agaactgctg ctgttgctgg tttggctatt gatacttttg
    54121 ctaaaaaaga ttttaatact atttctatta tgggtttagg tgtaactgct tctgctataa
    54181 tgaatatgct ttcgtatact cttaaagata aaaatataaa tataaagtta cttaaatata
    54241 aagaccaagc agagtcattt gtaaaaaagt atgaaaaaaa tgaacaattt agttttgaaa
    54301 tatgtgatac acatgaagaa cttattgtag attcagatgt agttatttct actgtgacat
    54361 atacagatga atatttatca gaatttaaat ggtttaaaaa aggtgcttta ttattacctg
    54421 tacatgttat gggatttgga aatgttgatt atctatttga taaagtatat ttagatgatt
    54481 ataatcattt gaaacatcta gaaaatatag atagatataa atattcttgt gaattttatg
    54541 atgttttaag taaacaagct aaaggaagag aaaatgatga tgagagaata atatcttaca
    54601 atataggttt gtcaatacat gatatattat ttgcaaacaa aatttacgaa ttgtgcgaaa
    54661 cactaaattg tgaagagata gaattaaaag aaccaaaaga aaaatattgg atatagttta
    54721 tttcattcat atttacaata atttattgta aatatgaata tgaagtaata tattattaga
    54781 aaattagcat gaataggata gataaattta tggataaata taatttaatt aagttcttat
    54841 ctattggaaa cgaatatata ggaaatttag ttgcattaga atcaaataaa gcaatacctt
    54901 ttgatataaa gagagtttat tacatatatg atgtaccaaa caatgtaaag agaggatttc
    54961 atgcgcacaa aaacttggaa caagtactag tttgcctaaa tggaagtgtg aagataaaat
    55021 gttatgatgg tgtaaaagag agtatattta atttacataa aaatgatgtt ggattgtata
    55081 taggaacggg agtgtggcat gagatgtttg actttgatga aaaaactgtt ttaatttcta
    55141 tagcatctga acattacaat gaagaagatt atattagaga ctataaagaa tttttaaagt
    55201 atttaaataa tatgtagtta ttatacagtt agtgatgtat tttcttaatt aaataaattt
    55261 aagatagcca tatagagaat aaatagatta ggatgtgaat ttattgttgg ttaaatttaa
    55321 taatttatta aaacagttcc aaattcataa agaagaatat gaacagaaga ttaaggatgt
    55381 aatggaaagt ggatattata tccttggaaa tgaagtaagg cattttgaag aagaatttgc
    55441 tagctatgta ggtagcaaat attgtgttgg tttagccagt ggtttagatg cacttataat
    55501 tgcttttaga gcattaggaa taagtgaagg tgatgaagta atcgtgcaat caaatacata
    55561 tattgctagt gttatgggaa tcagcataaa tggagcaaca ccagtatttg tagaaccaaa
    55621 tgaatattat aatatagatt catctaagat agaagaaaag ataaatagca aaacaaaagc
    55681 tatattagta gttcatttat atggtcaagc aagtaaaatg aaagatatac aagaattatg
    55741 tgataagtat aacttgtatt taattgaaga ttgcgctcaa tctcatggag ctaaatatga
    55801 tggaaaaatg acaggaacat ttggtgatat aggttgtttt agtttttatc caagtaaaaa
    55861 tttgggtgca tttggagatg caggagctat agtaactagt aatgaggaaa tagctgataa
    55921 agtgaaaatt cttagaaact atggctcaga aaagcgatat tataataaat ttgtcggata
    55981 taattcaaga ttggacgaaa ttcaggcagg tttattaaga gtaaaactta aatatctaaa
    56041 tgaaattgaa attgaaaaat caaaaatcgt agatagatat cttaatgaaa ttaataatcc
    56101 caaagtcata cttccaaaga tagaaaataa ttgtactcat gtatggcact tatttgtttt
    56161 acaagttgaa aaacgagata catttatgga atacttaaag aaaaatggta tagagtctat
    56221 aatacattat ccgataccac cacatctatc tgaagcatat gcttatttgg gatataaaaa
    56281 ggggagtttt aatatagctg agaactattc agataaagtt gttagtatac ctttatttgt
    56341 cggtatggaa gatgaagaag ttagttatat aattaaaatt ataaatgaat attaaactaa
    56401 tcataataat atcaaaaata aattttttat atatcattta tttaaatttc gttaattgac
    56461 atttttaaat attgatatat tgtacaaata aaattgaaat atatggaaga atatagaata
    56521 aagatgagat ttgtctaata tttttataaa ttaaaaatat tttcaaagag tttattataa
    56581 aattgtagac tatagtgttt ataatctttg taattattgg taactaaatt taaaaaataa
    56641 aatatttaat tatacacaaa aaagatattt aaaaaatttg ttatttattg tatacttaag
    56701 ttaaaactaa ataggcaaat ctagagaaat ctagtgacgc aaagctatag ggactaaggt
    56761 ttgtatacac aaactatgtc agccagttgc caaaaagagt tctaggtata ttgtatacgt
    56821 aggaagagtc taggatgact gcctttttgg tggtcatttt gttatggaaa aaatcacatt
    56881 atgtagtaaa aaacacctat aataacatat tataccaaat ataatttaaa ataaagataa
    56941 attatctata a
//
LOCUS       DACTZW010000016        56180 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.016, whole genome shotgun sequence.
ACCESSION   DACTZW010000016 DACTZW010000000
VERSION     DACTZW010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 56180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56180
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.016"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            323..2512
                     /locus_tag="JAM15_05215"
     CDS             323..2512
                     /locus_tag="JAM15_05215"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobalamin-dependent
                     ribonucleoside-diphosphate reductase"
                     /protein_id="HAT6797662.1"
                     /translation="MKYIIKRDGTKELFSKSKIEDAVYKASINSEGGVDRELAYDISR
                     KIANDYNSMEKCLSVEEIQDIVEVLLMESNRKDIAKHYILYRERRSEIRTKAWEFDEL
                     QKSIWKNKYRHNGESFDEWIKRISNNSSRISKLIRQKRFLFAGRILANRGLQKEGKKV
                     TYSNCYVIEPPKDSIEDIFDTAKKLARTFSYGGGVGIDISKLRPKGAKVNNAAKHTTG
                     AVSFMELYSMTTGLIGQRGRRGALMISMDVNHPEIEEFIDIKTDLEKVTKANISIRVT
                     DEFMQAVREKKLYNCTFEVETTGEKIVKIVNAYDLFNKFVKNNWDYAEPGILFWDKIK
                     TYNFMSEDKNFCFSGVNPCAEEPLPSGGSCLLGSINLSEFIIQPFGEHATFDINKLKS
                     CVREAVVALNDVLDEGLNLHPLQEQRDSVHKYRQIGLGVMGIADMLIKMGIRYGSDES
                     LELCDLIGKTMLNEAVKQSALIAKEYGTFSEYKYENISKSKFFIENLNEDTKEMVKKY
                     GLRNSQLLTIPPTGSISTMIGISGGIEPIFNLSYIRKTESLHDEDVYYKVYTPIVKEY
                     MDKKGITDEECLPDFFVTAMNIGYEERINMQKVWQKYIDASISSTINIPFETTVEDVF
                     NIYIKAWEAGLKGVTIFRDGCKRSGILINEKKEENNKEDKKENSKKEYYKNNKKEKDN
                     KDEKAKEIINKNFEEDEKFVCPECGSEGIAHTGGCSICLKCGYSGCN"
     gene            2580..3347
                     /locus_tag="JAM15_05220"
     CDS             2580..3347
                     /locus_tag="JAM15_05220"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HAT6797663.1"
                     /translation="MQDKSVREIKEKIETLEVEKYMEYIELLRVDERKSVQGLAIKLA
                     KKLDNIRKEEERLETINIFENEGYDKGYLYIGGIDEAGRGPLAGPVVASVVVFKKDTK
                     IEGVNDSKKLSEAKRDELFEVIKEEALDYGIGIVNNEEIDEFNILNATYMAMKKAINC
                     LKKAPDYLLVDAATIPGIDISQNPIVKGDSKSISIAAASILAKVTRDSIMYQYDRVYP
                     EYGFKSHKGYGTKEHYEAIEKYGITPIHRKSFLKNIL"
     gene            3405..4421
                     /locus_tag="JAM15_05225"
     CDS             3405..4421
                     /locus_tag="JAM15_05225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HAT6797664.1"
                     /translation="MEYNELLKSARENLNGSCKVCKVCNGVACAGEVPGMGGKGSGSS
                     FIENSKSLEKVKVNMRVIHDVSNPDTSIEMFGKKMSAPIFAAPVTGTTLNMGGKINER
                     DYIEPVVAGCANSGIYAMVGDTAVDAFLMENLDVVKKYNGAGIVFIKPWDNENIIKKI
                     RLAEEAGAFAVGVDIDACGLVTLSLHGKPVLPKNVKQIKELVKSTKLPFILKGIMTVE
                     DALMAVEAGVYAIVVSNHGGRVLDCTPGACEVLPKIADAVKGKVTILADGGVRTGLDV
                     LKMIGLGADAVLIGRPFVTASFGGATDGVETYVNKLQSELSSSMILTGCQTIKDIDGK
                     VIYK"
     gene            4487..4735
                     /locus_tag="JAM15_05230"
     CDS             4487..4735
                     /locus_tag="JAM15_05230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797665.1"
                     /translation="MSRKAYEEALVELEKFIDERKEIIKSAEDCIDKYIVDRTLPFDY
                     KDKCVEWQQELLDIAEAQILEANELSVLLQEKKELEED"
     gene            complement(4910..5407)
                     /locus_tag="JAM15_05235"
     CDS             complement(4910..5407)
                     /locus_tag="JAM15_05235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HAT6797666.1"
                     /translation="MYKIGESVMYPKEGACSVNDIVTKKINHEMQKYYELSVIFNSNL
                     KISIPVLNADRIGIRPVMDGNDVDNFIQSINKTDGVWIFDRKERLKLYQDKFHSGDVF
                     EIVKLIKMLMIQDSSKQLCSTDKEFLNKAQKFALSELAAAQCKSYTMVLEEMKKHILN
                     SKNTN"
     gene            complement(5651..6715)
                     /locus_tag="JAM15_05240"
     CDS             complement(5651..6715)
                     /locus_tag="JAM15_05240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6797667.1"
                     /translation="MIRLTIANIKRYLKNHTLLINMVMLPIILIFSLNFFINNSGNQS
                     MYFSPVAIVSDSSGKYEHKLINSSKLKENSFRLNEQDKAMNLLKNNKVSAVFVLDKNF
                     SNSIDKLQRPVVKCFKIENGGGSLWAESQIESFITKSLKLKVDKNIDDKLTKTNIIDN
                     KPDKNKGSFLVVFLICYFMYINAAHLASDLFTLKKSNVLKRLISTDNKDIKIIFSIFL
                     GLFFIQSIVYTFALLCFSIIEDFNLSLNVLMIVLANSFVSTGFVFWVARVFKNESSIS
                     LISTFYSLIGLAISISSLIPSMDKLSFMTNLSKFTPFYWTIDAIKNNGSILINIIALI
                     LIGIIFVTAGSLKLRDFAKN"
     gene            complement(6718..7815)
                     /locus_tag="JAM15_05245"
     CDS             complement(6718..7815)
                     /locus_tag="JAM15_05245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6797668.1"
                     /translation="MKLYMSVKTMLKSLKSSFILNLIYFLALPLILSWFLGMVTESMF
                     QNPIKTESTPIVIYDKDNTRLSNDLTKYLKNDLSYILTVKKDDSKAELKLTIPKGYES
                     SLLNEKSNTLNIEKLGTRDDIAILLQDILDTYHEKFYLNNSQKISSEDFSKLFNKNSI
                     DTSIINNNVKQSSYEYFALVSLGFLVIIFIMNNILSNYISESKGLSKRLYSMPITRVQ
                     FLIYDFVGLWIYSFIFLLLYVLFFRILGITFKGNFAILLLLCALSSYFMTSISTFVTS
                     FFSKKYGTAIVYALLFLQTIFGGIFSMISDTFTKLTSLSPTYLIGELFSNYETFKTID
                     SIGNLIFTCLIISTILIALAIVKEKYKWREV"
     gene            complement(7829..8764)
                     /locus_tag="JAM15_05250"
     CDS             complement(7829..8764)
                     /locus_tag="JAM15_05250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6797669.1"
                     /translation="MDIVRVNNITKRFNDKLVLDNISFSVKKGEIFGLIGPNGAGKST
                     LINIITNLMLPNSGSIQINGLDLSKDYIKAKSIIGLVPQELAIIETLTPFDNLEYFGA
                     FYGLKGKLLKERIIEALEVTGLTEVKKKKVKKLSGGMQRRLNIGIALLNHPKILILDE
                     PTVGVDPQSRNHIFNFIKDISKKHETTVIYTSHYMEEVEHLCSKIFIMDEGKEIAFGD
                     NDYLKSLVSTNTKLIMEIKNINAQLIFDLKNTKGVISVLENNSLLELDIDKKLQLTDI
                     LSVIDKNNSKIMKISYEEPSLEDVFLNLTGKNLRD"
     gene            complement(8893..9540)
                     /locus_tag="JAM15_05255"
     CDS             complement(8893..9540)
                     /locus_tag="JAM15_05255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6797670.1"
                     /translation="MNKIKVLIVDDEKLIRKGLKIILSSYNDLEIVGDASNGYEALEF
                     CKMNDVDIVLMDIRMKVCDGVLGTRLIKEYNNSITLLILTTFNDDEYIKDAMKFGASG
                     YLLKDSSDEVLHEGIRSSFFGNIVLDKSVAEKIMTSEKTVKQEHLYDMYNLTEKEISI
                     IRLIANGLNNKEISQELFLSEGTIKNNITNILAKLELRDRTQLAIFAFKNKIVIE"
     gene            complement(9533..10696)
                     /locus_tag="JAM15_05260"
     CDS             complement(9533..10696)
                     /locus_tag="JAM15_05260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAT6797671.1"
                     /translation="MNREKLVAFIRYLSLFILVVSYLKNVENTLYPVITMIILFLIII
                     NNQVRFFSLSNENKFILISYFLELILIFILCNYTKTFNSIYFVPLILDISFLIKEKYK
                     YILFSFVIISSLVISLDKNIYLALESSSILLIITVLSIYIENENLSKLYSQNLYDKLR
                     ISKDELKKVNADLETYASSIEELAILKERNRISREIHDSVGHSLSTTIIQLNAIEKLL
                     KDKPLIYDLVHELREFVTESFQDVRRAISELKPVEYENYQSLFKIKELVKSFIKLTNI
                     NVKLTISKNTWNLSRNQSIALYRLIQESLSNSSRHGKATEIRIFITFNTSNLIITISD
                     NGIGCGNIKKGNGLNSINERIYELNGKVEFDNSNNGFTIRASFPKFSGGDFFE"
     gene            10880..11224
                     /locus_tag="JAM15_05265"
     CDS             10880..11224
                     /locus_tag="JAM15_05265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HAT6797672.1"
                     /translation="MNNKEKGDFGEKVAVNYLLSKGAKILEKNYRLKIGEIDIIAKME
                     DEIIFVEVKSRSNIKFGYPCESVSFKKRKKIIGVASYYIIKNNLNNTPIRFDVIEVYL
                     LEKRINHIMNAF"
     gene            11255..12856
                     /locus_tag="JAM15_05270"
     CDS             11255..12856
                     /locus_tag="JAM15_05270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
                     /protein_id="HAT6797673.1"
                     /translation="MLSIINSSNLVGIDSFLVKVEVDVSNGIPSFNIVGLPGKEIKEA
                     RERVKSAILNSGYKFPSTRIVVNLSPADIKKEGAFLDLSISIGLLRELIKKDENYIRE
                     SMFIGELSLDGKIRKVRGILPIIMGAKTQNIKRIFIPIENIKESLFVDEIDIIPIKSL
                     KECVDFLNEEIKVDKVRIMSFLDDKSRKENEELEKDNSYIDCKYTKINNEESKYDEDF
                     KDVKGNYFVKRSAEIAAAGNHNMFMIGPPGSGKTMIAKRVRTILPDISIEEMIEVSKV
                     YSILGMINETKGIIDKRPFRAPHHTTTKQSLIGGGMDARPGEIALAHRGILFLDEIAE
                     FDRKILETLRQPIEDGYVNISRVKYSAKYPCRVLLVAAMNPCPCGYYMSETECRCRSN
                     EIDRYINKISGPLLDRFDIFVEVNSIKYSDFNSLKQEESSQKIKRRVENARKIQINRF
                     KKDNIKNNSEIKAYNLFKYCKLEKEASKTAEMIFNKYNLSSRSYTKLLKMARTIADLE
                     ERDLINSQCIIEAFSFRKAYYSYFK"
     gene            12875..13975
                     /gene="dprA"
                     /locus_tag="JAM15_05275"
     CDS             12875..13975
                     /gene="dprA"
                     /locus_tag="JAM15_05275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HAT6797674.1"
                     /translation="MEKRDTYLWLKSIGGITTKTIEIIENEIVNIEDIFDFSEKEIYN
                     LKNISLNIRKNIVKYRGHAYLENIKELLYKKAIKYICKYDKEYPENLKNIYNAPKLLF
                     YKGDIGLVNNNFNIAIVGSRKPTAYGINCAKTISCQLSQYGVNIVSGLAIGIDAYSHI
                     GCMSGKSKTIAVLGSGVDNPLPKQNLHLSNKILENGGLLLSEYNINSTVAPYHFSNRN
                     RIISGLSDGVVVVEAAIKSGALITVDFALEHGKNVFAIPGNINSQMSRGCHKIIKEGA
                     KLIENIDDILNEYNIFNIIDKKINQKYDNISLNAKSKQIIEAIKREGNLHIDSICDYT
                     GIEIKYVNSIINELVLNELVVEMNNKTYSLNV"
     gene            14008..16095
                     /gene="topA"
                     /locus_tag="JAM15_05280"
     CDS             14008..16095
                     /gene="topA"
                     /locus_tag="JAM15_05280"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HAT6797675.1"
                     /translation="MAKTLVIVESPAKAKTIEKFLGKSHYTVKASVGHVRDLPKSKLG
                     VDIENNFEPQYINIRGKGDVIKELKKEAKKSKQVYLATDPDREGEAISWHLAHILNLD
                     ESEDCRIEFNEITKDAIKKAIKHPRNIDINLVDAQQARRVLDRLLGYQISPILWQKVR
                     KGLSAGRVQSVTTKLICDREKEIKAFIPKEYWTIDVEAKTVKDKDITLKFYGKNDEKI
                     ELENEEAVNEILKEMEGKDLKVEKIESKSRRKSAPKPFTTSMLQQEGANKLFFTTKKT
                     MMIAQELYEGIDIEGEGTVGLISYIRTDSKRISDEAKEKAKGYIVNNLGENYYKNTGD
                     KKEKKDTKKVQDAHEAIRPTSVDRTPESIKASLSKDQYKLYNLIWRRFVASQMEDSVF
                     DILNVECKIGDIVFKATGSKMKFDGYTKVYNFSEREDKILPSIEKGDILNIENILPDQ
                     HFTQPPARYTEASLVKTLEELGIGRPSTYAPTIATILNREYVEKQGTSLCPTELGIIV
                     TDILENNFHKFIDVDFTADMESKLDVIEEGNTDWKKIVSESYAPLKEAIEEALENIEK
                     VNMDEETDEICENCGSNMVIKYGRFGKFMACKNYPDCKTTRPIMNKIGVKCPKCEEGD
                     IILRKSKRGKAFYGCSNYPNCDFVAWNKPTGEFCEKCGSYMVEKVTKSETKTVCSNKE
                     CNKETKEHNDGKE"
     gene            16260..17045
                     /gene="codY"
                     /locus_tag="JAM15_05285"
     CDS             16260..17045
                     /gene="codY"
                     /locus_tag="JAM15_05285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HAT6797676.1"
                     /translation="MASEVLQKTRKINKTLQTSGGSSVSFDLLAGALGDVLSSNVYVV
                     SAKGKVLGLHLNDVQDSSVIEDEYTKQKKFSDEYTQNVLKIDETLENLNGEKILEIFP
                     EEHGRLQKYTTVVPILGSGQRLGTLVLSRYSNSFNDDDLVIAEYSATVVGLEILRAIG
                     EELEEEMRKKAVVQMAIGTLSYSELEAVEHIFAELDGKEGLLVASKIADRVGITRSVI
                     VNALRKFESAGVIESRSLGMKGTHIRILNDKLTDELKKLKNNQ"
     gene            17152..18417
                     /locus_tag="JAM15_05290"
     CDS             17152..18417
                     /locus_tag="JAM15_05290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HAT6797677.1"
                     /translation="MPLADKIRPKTMNDVIGQSHIIGNGKILSKILQSNFLPNMIFFG
                     PPGVGKTTVAEIIAERSNKSFYKINATNSSLEDIKKVISELGSINNVNGVLLYIDEIQ
                     SFNKKQQQSILEFMENGSITLIASTTENPYHYVYKALLSRSTVFEFKPLEKLDIEKGL
                     KRAVEVLNEDSYMDIECNNDAIEDIAILSDGDMRRALNILEVVVYSTKPNKDNITYID
                     SDVIRASTFNKIINYDKNGDSHYDILSAFQKSIRGSDPQASIHYLARLIKGGDLISIC
                     RRLLVIASEDIGLAYPNAIVIVKACVDSAMQLGFPEAKIPLAEATILLATSPKSNSAC
                     IAIMKAMDELDKEFVKDIPNSIKDAHYSGSKEIGRGCGYKYPHNFKNHYVKQQYLPDS
                     IKDSIYYIPQENKTEKNIKKYLEYLNSDF"
     gene            18448..19218
                     /locus_tag="JAM15_05295"
     CDS             18448..19218
                     /locus_tag="JAM15_05295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAT6797678.1"
                     /translation="MIIKLNSTYHSRVMKYLKKEPEYNLFIIGDIERYGYGNNFLNIW
                     ADVGEHGEIKAILLKYFEFMMFYSDGEYDVEGFYNLLRNTNYEEISGKICAVDTLAKR
                     LGLNNLKVVDFCKLQTKKFLIDNNCNAKVKRIRLGNLKKTVKLYDLIDEFHSTTLENL
                     KNGLRTGRGYCIEINKQVVSMAKSTSENRTHAMIIGVGTHPKYRAKGLATKCLIKLCS
                     ELLRENKIPCLFYDNEEAGKIYKKLGFENIGKWGIYSK"
     gene            19327..19773
                     /locus_tag="JAM15_05300"
     CDS             19327..19773
                     /locus_tag="JAM15_05300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HAT6797679.1"
                     /translation="MKLSTKGRYGLKAMFELALNQDNGPVSLKFIAKKQKISDQYLEQ
                     IFSSLKKSGLVKSVRGAQGGYLLSKNAEDITVGDILVVLEGPVALSDCVLDEDVCENS
                     NMCVTKIVWEKMKKGIEDVIDSITLKDMINDYNKNKLENDITNIKK"
     gene            19791..20984
                     /gene="nifS"
                     /locus_tag="JAM15_05305"
     CDS             19791..20984
                     /gene="nifS"
                     /locus_tag="JAM15_05305"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase NifS"
                     /protein_id="HAT6797680.1"
                     /translation="MEKRRLYMDYSATTPIKKEVLDAMMPYLTDYFGNASSFHTFGRE
                     AKDALDKAREQVAALINAEPSEIYFTAGGSESDNWTLEGVAYANKNKGNHIITSKIEH
                     HAILHTCEYLAKHHGFEITYLDVDSEGKVDLKQLEDSIKDTTILISIMFANNEIGTIQ
                     PIKEISEIAKKHKILFHTDAVQATGNIPVDVKELGIDLMSMSSHKIYGPKGVGALYIR
                     KGVRLHNFVHGGAQEKSKRAGTENIPAIVGYGKAAELAKENMQNHVETLTRLRNKLID
                     GVLERIPYTRVNGSLENRLPGNANFAFQFIEGEGILLLLDMLGIAGSSGSACTSGSLD
                     PSHVLLAIGLPHEIAHGSLRLTVGDFTTDDDIDYILENLPKVIERLRSMSPLYDDAKK
                     QGLVK"
     gene            21038..21478
                     /gene="nifU"
                     /locus_tag="JAM15_05310"
     CDS             21038..21478
                     /gene="nifU"
                     /locus_tag="JAM15_05310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold protein NifU"
                     /protein_id="HAT6797681.1"
                     /translation="MQYSDKVMEHFMNPRNMGEIDNASGVGEVGNPTCGDIMKIFLDI
                     DGDVIKDVKFKTFGCGSAIASSSMATEMIKGKTIKDALELTNKAVAEALDGLPPVKMH
                     CSVLAEQAVKAALIDYAQKNNIHIPELDGYVIDDAHDHDVEEEE"
     gene            21767..22846
                     /gene="mnmA"
                     /locus_tag="JAM15_05315"
     CDS             21767..22846
                     /gene="mnmA"
                     /locus_tag="JAM15_05315"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007060651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HAT6797682.1"
                     /translation="MNKKVMIGMSGGVDSSVAAYLLKQQGYDVIGVTMKLWQDDDVVE
                     IEGGCCSLSAVEDARRVANKIGIPFYVLNFREVFKEKVIDYFIDEYLEGKTPNPCIAC
                     NKHIKFDDFYKKARQIGCDYVATGHYAKIEKDESTGRYLLKKSVTDKKDQTYALYNLT
                     QEQLEHTLLPIGDYEKDRVREIAKEMGMAVYNKPDSQEICFVKDNDYANYVKKHSKKR
                     IEEGFFVDTKGNILGKHKGILYYTIGQRKGLGITFGKPMFVIDINPINNTIVLGDNED
                     LFKKELIAKDVNFISIDTLEEPLRVQAKIRYSAKPSPATIHRVGEDTIKIVFDEAQRA
                     ITKGQSVVMYDGDIVVGGGIIEKSL"
     misc_binding    22992..23229
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            23297..25936
                     /gene="alaS"
                     /locus_tag="JAM15_05320"
     CDS             23297..25936
                     /gene="alaS"
                     /locus_tag="JAM15_05320"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HAT6797683.1"
                     /translation="MEKMGLNEIRSKFLEFFESKGHYVANSYSLVPNNDKSLLLINSG
                     MAPLKNYFSGVEVPPSVRMCTSQKCIRTGDIENVGITARHATFFEMMGNFSFGDYFKR
                     ESIKWGWEFVTEWLNIPEDKIWVTVYEEDDDSYDIWAKEMNFPEERMVRLGKDDNFWE
                     IGTGPCGPCSEIYFDRGEEYGCDNPDCKPGCDCDRYLEFWNHVFTQFDRDEEGNYSLL
                     ENKNIDTGMGLERMGCIMQGVDTIFEVDTIKSILEAVEKLTGVKYGENPKNDISIRII
                     TDHIRAVTFLVSDGVLPSNEGRGYVLRRLLRRAARHGKLLGVKELFLQKLIDEVIKVN
                     DKAYPVLVEKESYIKKVVGIEEEKFNETIDQGTEILNSYIEVLKNEGKTVLSGQEAFK
                     LYDTYGFPIDLTKEILEEEHLSVDEEAFNEEMEKQKERARNARGNMDGESWKEDPLSK
                     LESTVDSTFNGYSEIYGEGTIEAIVKDDELVQSAEEGDKVSIVLDNTTFYPEGGGQVG
                     DCGLITNENLVLEVLNTKKGANNSIKHIGIIKSGRISNGDKVKTLVDRETRMSAARNH
                     SATHLLHKALREVLGEHVNQAGSLVTPERLRFDITHFEAISNEELKVIEEKVNNVILS
                     SLDIKCDIMNIKEAKEKGATALFGEKYGDEVRVVSMGDYSTELCGGTHLTNTSQVGMF
                     KILSEGGVAAGVRRIEAITGKAVYEYLKERDGIISEVCVNLKSKEDNLIQRISSLLEE
                     NKNLSKELHDMKAKMSLQSVDSIFDSKVEVNGVNLITNKFEGMDMDTLRETADNLRDK
                     LGSGVVVLANVVDDKVNFVVTATKDVLDKGIHSGNIVREVAKIAGGKGGGRPNMAQAG
                     ASDVSKVDQALSYASEVIKTQVK"
     gene            25961..26218
                     /locus_tag="JAM15_05325"
     CDS             25961..26218
                     /locus_tag="JAM15_05325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HAT6797684.1"
                     /translation="MEKDLDYTMKFEGIPEDRMSVGDTIDFVYKALVEKGYNPINQII
                     GYLLSGDSSYITSHKNARAIIKKFERDEILEEVITHYLNRK"
     gene            26228..28399
                     /locus_tag="JAM15_05330"
     CDS             26228..28399
                     /locus_tag="JAM15_05330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797685.1"
                     /translation="MRKKIMSLFAIVIMIFVSTASYGFAEEKGKVIFIDMNRTNLGSM
                     MNIPILKNEIEKRGYVALMNIRGDQGTDDRRSYASMGAGTRASVTTEDYINFQKVDQD
                     TAKAFEVATGQKAKEINDLGINRSINENLEYGEYGANLGSLGKTLSENGLKTSVIGNA
                     DIIENNQLVKNRNLCLVAMDQYGRIDSGNIDNINKKDSKMPFGISTDYDKLLDETKKS
                     YKNSDAIFVELGDTYRLDMYRLNLNDNTYGTMKKNIVKNINKYLEQVFSMVGENDTVY
                     IASAFPSDLDYKNKRRLSPIIKFSGEGKGLLESATTRKAGIVANLDVGVDILGTFGLE
                     NKEMVGRSYTLVNKEDNVGYLKSLYERIVSISSIRSTIINGFVGVISASWVIAMFAIF
                     FRNYMPHKERVFKVLKEFIKLGIIMPLSFMLAPLMNFKTPISISLGIFATTLILYLLG
                     RKLFKDNDIKHMGFFATLTILVIVIDSVFGTYLMQNNIMSYDAVIGARYYGVGNEYEG
                     VTIASAVFGLAVLLHYKKVSKLLVVIFSLIILITSAYPSMGANVGGAISECVAYLLFI
                     MLIYDIKIDFKKAVLLAVSAVVVVFAFAALDILSGSESHLGMFVQRIFLNGPGEILQT
                     FGRKIQMNMQLAQTSVWVNILLVGIGVIAVLIFKPSRHFRKIMNNFPILFKGFIASMV
                     GCIITLLVNDSGIVAASTASIYILIPLIIININMIIFEKNN"
     gene            28605..29030
                     /gene="ruvX"
                     /locus_tag="JAM15_05335"
     CDS             28605..29030
                     /gene="ruvX"
                     /locus_tag="JAM15_05335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HAT6797686.1"
                     /translation="MLDGRIMGLDVGDKTIGVAVSDLMGLTAQGVKTIKRVGKKKDIE
                     ELKAIIKEKQVNKIVSGLPKNMNGTLGPQGEKVIKFCELVKAETGIDVEFWDERLSTV
                     AAERSLLEADVSRQKRKKVIDMLAAVIILQGYLDFKINS"
     gene            29108..29395
                     /locus_tag="JAM15_05340"
     CDS             29108..29395
                     /locus_tag="JAM15_05340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HAT6797687.1"
                     /translation="MEENIINLIDENGVESQFEIILTLEAEGKEYAILMPLDDEEAEE
                     ALIFRIDEDEEGEILIPLESDEEYETVVAVYTAIMEEEGLNYDEDESNGLN"
     gene            29677..30135
                     /locus_tag="JAM15_05345"
     CDS             29677..30135
                     /locus_tag="JAM15_05345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAT6797688.1"
                     /translation="MANTMDLLKDKLKETGFKITPQRRAIVEILLKHDHSHLSSEEIY
                     DLVRVDCPEIGLATVYRTMQLLDEIGLISKLNLDDGCIRYEISLHKEDCHNHHHLICK
                     NCGKIMEAKEDLLDNIEKEIQSLYKFKILDHDVKFYGLCDECNGVSDSEE"
     gene            complement(30252..30989)
                     /locus_tag="JAM15_05350"
     CDS             complement(30252..30989)
                     /locus_tag="JAM15_05350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HAT6797689.1"
                     /translation="MRGKTHCAIGILTAIQTSLIFKIPISLVDILVSATFAVLPDLDK
                     SNSMVSNFILKNNVSKYIYRIFIYAVNIIIFFISININDNFYLSAIITFVAIIIIEAK
                     LTHTFLRKVFLSLIFILLAICLYIIEVEIYFTIFCLMLSIFPWLKHRSFSHSIFATII
                     VYFLLKQIELITNINNLSFYGTIGYASHMFLGDLFTKQGIPIFYPLSEKKISLGFLTV
                     GGPFSNFIEKSFIFVLIGLIIFSILKL"
     gene            31212..32882
                     /locus_tag="JAM15_05355"
     CDS             31212..32882
                     /locus_tag="JAM15_05355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002845950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HAT6797690.1"
                     /translation="MFKKNTNKIKVMALGGLNEVGKNMTVVEYKDEIIVIDAGLSFPE
                     DEMLGVDIVIPDITYLVKNRDKIKGIFITHGHEDHIGALPYILKKINVPVYGARLSIG
                     LIQVKLKEHKMNNVKLNVIGPRQVIKLDNMEVEFLKNNHSIPDAYSIAIHTDQGIIYH
                     TGDFKIDLTPIDGDVMDMHRICELSKKGVLLMLADSTNAEKPGFTMSEKTVGVGLDEL
                     FAKGNGRRIIVATFASNIHRLQQIINTAEKFNRKVAISGRSMVNVVGVAKELGYLDIS
                     DDMLIDLNDICKYEDSELVIITTGSQGEPMSALARMAFSEHKKVEIKSGDLVIISAHP
                     IPGNEKLISRVINFLFEKGAEVVYSDIADIHVSGHACQEELKLIHALVRPKFFMPAHG
                     EYRMLKRHAEIAEQLGMDKENIFVMQTGDVLELDKNSAKVANRIQTGNILVDGLGVGD
                     VGNIVLRDRKHLSEDGLMIVVVTISKDEGKVLAGPDIISRGFVYVRESEDLMDGAKDI
                     IKNVLNECEEKNIKEWAYLKNNIKENLKEYLYQKTKRNPMILPIIMEV"
     gene            33088..33288
                     /locus_tag="JAM15_05360"
     CDS             33088..33288
                     /locus_tag="JAM15_05360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protein"
                     /protein_id="HAT6797691.1"
                     /translation="MDDVSRQNAIKALKQTKMEIAGEYGMNYEDAFEIIENASNKGVL
                     EGYFKKLEKKKNLGQGISRHLE"
     gene            33342..34505
                     /locus_tag="JAM15_05365"
     CDS             33342..34505
                     /locus_tag="JAM15_05365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HAT6797692.1"
                     /translation="MKKLASTALAILIALTPLSFSFANNKENADANQLNISSKSAILM
                     DVGSGQILYEKDAHKKLPPASVTKVMTMLLIVEALDSGKIKLDDEVQVSETASSMGGS
                     QIFLEPGETQKVDTLLKGIAVASANDACVAMAEHLAGSVEGFVDRMNAKAKELNMNDT
                     HFANTNGLPVANHYTSAHDIALMSRELLKHEMISKYLTTWMDKVVVGKKQVTVGLANT
                     NKLIKHYQGATGVKTGFTQEAKYCLSASAKRGNTHLVAATLGAETSPERFNDASSLLN
                     YGFANYESVKLCSKGDNIATLTLDKADENKVKLVAKEDLNALIKKGSSKEFEKKIEIV
                     KNPKMPIKKGTVLGKIKICKDKKVIGEVELINTKDINKASYLQMLQRIIDNMI"
     gene            complement(34716..35138)
                     /locus_tag="JAM15_05370"
     CDS             complement(34716..35138)
                     /locus_tag="JAM15_05370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016285909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2000 domain-containing protein"
                     /protein_id="HAT6797693.1"
                     /translation="METKNSKCVMVIDENLPMGIISNTAAIMGITLGKHAPETVGPDV
                     IDKTGNSHLGIIDIPVPILKGNKEIIKDLRKKLYTLEFNDLTVVDFSDVAQSCNLYEE
                     FTQKIASVPEDELQYFGIAIYGNKKKVNKLTGSMPLLR"
     gene            complement(35159..35995)
                     /locus_tag="JAM15_05375"
     CDS             complement(35159..35995)
                     /locus_tag="JAM15_05375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAT6797694.1"
                     /translation="MRQEERTVCFDRELKIEAYRFKGIMQKFPNHFHEHYVIGFIEKG
                     QRYLSCKNKEYTTSTGDLLLFNPFDSHTCEQIDDKVLDYRCINIKPEIMKKTVFEITG
                     KNYLPKFNQPVIFRSELVPLLQELHYIIMEEELDFKKEELFFFLIEQLIEEHTEPNLQ
                     SNLENTNIEIQAVCDYLENNYAEHIVLDELSTIAGMNKYSLLRNFTKLKGITPYRYLE
                     NIRVNKAKKLLEKGVEPIDAAIQTGFVDQSHFTNFFKNFIGLTPKQYQNIFINDDSNN
                     FK"
     gene            36293..36889
                     /locus_tag="JAM15_05380"
     CDS             36293..36889
                     /locus_tag="JAM15_05380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HAT6797695.1"
                     /translation="MLSMNIGEIVASLVGIAMAISIHEFGHAYSAHLLGDDTAKAYGR
                     MTLNPVRHVDPIGLLAMFILKIGWAKPVPVNPNNFKNYKIGNLIVSLAGVFCNVLTAI
                     LCVIINKYVHMYAINTIAGYVLIYSMGFAAFNLLPIPPLDGWGVISTFVPYKWNEYLY
                     KFESMSYIILLIALFTGIYQIILSPIYTVLLKIVYLFV"
     gene            36919..37638
                     /locus_tag="JAM15_05385"
     CDS             36919..37638
                     /locus_tag="JAM15_05385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HAT6797696.1"
                     /translation="MKYNIQLQVYEGPLDLLYDLITKHKIDIKDISIIDITKQYLNYL
                     KMLDKMDLEITSEFITMASKLLEIKSKYLLYKQKDEEEDPRIELMEKLEEYRKFKVAS
                     QDIKENITYVNERFYRNKEEIIIDDNVDLEDISIEAIKNILPYIFKVKTSQIENANDE
                     KLDKIVRKKIISVEEKILYIRDIIKDKIEVTFTNIIKSYENDEIIATFLSILELIKEK
                     EIVVVQDIFFDDILIRKSSEC"
     gene            37640..38179
                     /gene="scpB"
                     /locus_tag="JAM15_05390"
     CDS             37640..38179
                     /gene="scpB"
                     /locus_tag="JAM15_05390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HAT6797697.1"
                     /translation="MKREDIKYIIESVMFAYGEPISIKELNYIINKELSSKEIEIMLN
                     LLIEEYREQNRGIQIIKLENKYQMCTNKDYAEYIKKIIEPKKKKSLSQATLETLTIIA
                     YKQPITKVEIEDIRGVKCDKVLQTLFENELIREAGRLNKIGKPIIYKTTDEFLKLLNI
                     ESLEELPPIENYQEVATNE"
     gene            38341..38970
                     /locus_tag="JAM15_05395"
     CDS             38341..38970
                     /locus_tag="JAM15_05395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2953 domain-containing protein"
                     /protein_id="HAT6797698.1"
                     /translation="MELNELFNFKYLIIAVIFIISVTMLILISHINILIIADINNKDI
                     CLKLNIKYMFNLININRQLYPAENSKNNDKKEGMKNNIDSSILLADDLLSIYRLLKKI
                     KIHELYSNINFGTGNIGLTSSVYVLINTLYGNLFNMIDAEKMYLNVNPDFTKDYVLGN
                     IRIHIRPRIKALFNIIIMINKIMNKNKGNKEGDSNESNRFDTESYGNNS"
     gene            38924..39352
                     /gene="ytfJ"
                     /locus_tag="JAM15_05400"
     CDS             38924..39352
                     /gene="ytfJ"
                     /locus_tag="JAM15_05400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YtfJ"
                     /protein_id="HAT6797699.1"
                     /translation="MRATGSIQSLMETTLETIKGSIDANTIIGDPIKTDTTVVVPISK
                     VTIGFGIGGGEYSKGYDDKDREIELKNEKSDTNFAGGSAGAISVQPVAFVVVESGETR
                     IMSLDSNINLVDNILSITPRVLEKIQNISQSNKNQDKNNM"
     gene            39600..40040
                     /locus_tag="JAM15_05405"
     CDS             39600..40040
                     /locus_tag="JAM15_05405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAT6797700.1"
                     /translation="MSDKELSILLLESMNNFHNLIKIINNERYKKDKVLTERQFFALV
                     KIRKHDKIELKNLSRDLHVSTSSLCILLNKLVEQEYVYREEDSRDRRNTFYGITKNGE
                     KILDNEILKFVSIISDKMDCLDIDNKDKLFTSLEESKNIIEQLF"
     gene            40056..41507
                     /locus_tag="JAM15_05410"
     CDS             40056..41507
                     /locus_tag="JAM15_05410"
                     /EC_number="3.4.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="HAT6797701.1"
                     /translation="MNIKYSKEILKSLENAITVVALFEGEDVSTTFDKINMISRNFNS
                     KENSIDTVTLVENNNLVNVCLVGFGKRELLNREKIRIIGGNLCKKLKNILKNEAYKSS
                     DVNVLNLNLNSDEIGSFVEGILLGNYKFDKYKTKSKDFERKEVDTITIFTEKEVECQI
                     EKAKILANSTIIARNLVNEPSNVIYPKTLAIETVKLGAEFGFNVDVYEEEKIKALGMD
                     AFFAVSRGSINKPRFIVMRYFGDKESTDILGLVGKGLTYDTGGYSLKSNASMLDMKTD
                     MAGAASVIGAMCAISQSKLKKNVIAVVAACENALSGGSYKPGDIISSMAKKTIEVLNT
                     DAEGRLTLADAIYYIINNEKVTKVVDVATLTGAALTLLGNVATPIVTNNDDFYCELEK
                     ATTLSGERVWKMPIYDEFKDMIKGEEADLKNTGGKNAGCITAGAFIGEFVGNTPWIHM
                     DIAGTSTSSKSIGYKAKGATGEPVRTLYYLAEI"
     gene            complement(41598..42266)
                     /locus_tag="JAM15_05415"
     CDS             complement(41598..42266)
                     /locus_tag="JAM15_05415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwaF family protein"
                     /protein_id="HAT6797702.1"
                     /translation="MFKIFLFSSEQFVSLFIFGLFLYYCPKLTKNILPYSYTVEKIIC
                     TLLVIIMALEQLLLISSGNYSTLNSLPIGINYICIYLCIAILIFKQYHLFNIFFSWSL
                     VCSVGELIFSKNLGYEFPSLIYFIFIFSKCLIIYADIYMVDVRKFRVNRYALRDNLAI
                     CFIYFSFIFLLNTFTNSQYYYGFLSHSTTAIFTFIFVTSIMYIPALLFNRDTFILEKK
                     KKSK"
     gene            complement(42850..43170)
                     /locus_tag="JAM15_05420"
     CDS             complement(42850..43170)
                     /locus_tag="JAM15_05420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HAT6797703.1"
                     /translation="MKLKTISLPELNNLDPTLESTFIKMGEEQGELAECIGKFRNLSG
                     ENNDLDEVDIIKKTAKELMDVAQTCVTMMFKLEEQYGINLDEIRKEHIKKLEKRGYIK
                     NMDK"
     gene            complement(43290..44027)
                     /locus_tag="JAM15_05425"
     CDS             complement(43290..44027)
                     /locus_tag="JAM15_05425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HAT6797704.1"
                     /translation="MDANSLKDLIANHNNIVFFGGAGVSTESNIPDFRSSTGLFSQKL
                     NKQFTAEQLVSHTFFVRYPEEFFEFYKDKLIYPNAKPNNAHIALAKLEEMGKLKAVIT
                     QNIDGLHQMAGSKNVLELHGSVHRNYCTKCGKFFDLESMLNLGGNIPYCDNCGSIVKP
                     DVVLYEEALDSDVITKTISAISNADLLIIGGTSLAVYPAASFIDYYKGDYIALINKAN
                     TVYDKSASLVINKPIGEVLYEAVLRQI"
     gene            44242..46065
                     /gene="acd"
                     /locus_tag="JAM15_05430"
     CDS             44242..46065
                     /gene="acd"
                     /locus_tag="JAM15_05430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosaminidase"
                     /protein_id="HAT6797705.1"
                     /translation="MKKKAALATLAMLPLGVVNAHADGDIGIVTINYLNVRNEPTAES
                     NIAFVAKKDDKVLIKDSSNGWYKIKAESGQEGWASSKYIAKSNSDSLRTSTNKEKQVI
                     SNSLNMRNGAGTSYRVITVLKKGQKVEVISESNGWSKIKYDGRLGYVSSSYLGDVSNS
                     TNKSKTKQVNTTSLNVRSGPNTSYGLLGKLPKGSKVEVISESNGWSKIKYNGKDAYVS
                     SMYLSDVSQSNSDNSSQSNDKKNTDKVVNTASLNVRSGPGSTYSKLGKVYKGSKVTVL
                     SESSGWAKINFNNKEAFVVGNYLSTSADTSNNNSNSNSDNSSNSNGNNSSSSGQVNGM
                     SGISGAKIDYKSLSYTLESHISKQVEKAASGGNVIAPSNRKSTPSPEFSTFSAQRTSS
                     FVNASSSDIEYYLNPKNFTNTTKGMMQFLKINSYRDGISESSLNSYLNGLSSSVFKNQ
                     GAAFINAAKKYNIDVVYLVSHAMWETAYGKSTLAQGQTLTSYKGQPLSKPVKVYNFFG
                     IGAIDKSANVSGAEAAYSNGWTSVEATIDGSAKWISQNYVNSSKYNQNTIYKMKWNYD
                     YTWHQYATDVNWANGISGIMENLIGLYGGGSSLVFEVPQYK"
     gene            46280..50578
                     /locus_tag="JAM15_05435"
     CDS             46280..50578
                     /locus_tag="JAM15_05435"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HAT6797706.1"
                     /translation="MESIKEYLDKLEINNSGLGKQLKEVYINRVVYFKEDKIVYFYLT
                     SKDIVSHELLDKFKEELMYKLDYFKDMRMKIRFTGLERKSNKDVIKKYWNNILYILKY
                     LCPSIAGWYKQVEFLCLEEELKIKLPKGIFYERLMKKNVTYVLKTVLSEELGLDLNIT
                     IEKAVDEKVNKERLIRINDREMEEKIRALEIGKVNNCEENEEESYVIKSDVDENLIYG
                     DNANAMIENIVELNASSGTVAVVGDIFDVDTKELKNGKILMIASITDYTSSISCKLFL
                     TDTNKDGVLENVKKGAYLKIKGDIVYDTYQREISMMISGIRKETRIEREDKSEEKRVE
                     LHAHTQMSSMDAICSVKKLVERAAKWGHSAIAITDHGVVQGFPDAMNAGKSNNIKILY
                     GVEGYLVEDDSLIIEDANDKELSQTFVVFDIETTGFSNTNDKITEIGAVKIENFKIVD
                     RFSELINPEKDISYKIQELTGITNELIKDKPTIEEILPKFMEFVGDSVLVAHNAEFDT
                     GFISQKCREQGLLYNNKKVDTLMLARVMLPNLKRHRLNVVAKELGIPLLNHHRAVDDA
                     EATALIFNKFLQMLTEKGAKTLSDVNNILGKIDYTKLSTNHITLIAKNSIGIKNLYKI
                     ISDAHVNHFFRAPRILRSVLNEYKEGLIIGSACEAGVVFQAVKKNMSDEEMKKIIDLY
                     DYIEVMPIDNNRFMIDKGEVKDEEELRELNRKLIDTAKKFDKIPVATGDVHFLDKHEA
                     VLRKVLKYSQGFKVDEEETYLHFRTTDEMLEEFSYLGEELAYEVVVENSNLIADMVED
                     IKPIPDDTYPPIIEGSDVELREMCYKKAKRIYGDPIPEIVQKRLDRELNSIISNGYAV
                     MYIIAQKLVAKSLSDGYLVGSRGSVGSSFAATMSDITEVNPLPAHYICENEDCKYSFF
                     YEIGEWGSGVDLPDKDCPKCGRKLAKNGHDIPFEVFLGFEGDKEPDIDLNFSGNYQPT
                     IHKYTEELFGEGYVYRAGTIGTVAEKTAFGYARKYVEENNISVPNAEVLRLSNGCTGV
                     KRTSGQHPGGVMVIPDYKDVYDFTPIQYPANDTSCGVITTHFDYHSISGRILKLDILG
                     HDGPTIIRMLEDMTGINITEIPLDDKETMSLFTSTEALGVTPEEINCPIGCLAVPEFG
                     TKFVRQMLLDTKPTTFAELVRISGLSHGTDVWVNNAQDLVREDIVGLKDVISTRDDIM
                     NYLIFKGLPPKMSFTIMESVRKGKGLKPEHIEEMKKNNVPEWYIGSCKKIKYMFPKAH
                     AVAYVMTSFRIAYCKVHYPEAFYATYFTTKVEDFDADLIVKGLDAIKSKINEIESLGN
                     DATTKEKGMLTVLEVALEMYARGIKLLPVDIYKSDATEFIVVGEKTLLPPMAAIQGLG
                     GNAAINIQNERKNGEFISKEDLRKRTKISKTVIETLTNHGSLENMSERNQLSLF"
     gene            50782..51243
                     /locus_tag="JAM15_05440"
     CDS             50782..51243
                     /locus_tag="JAM15_05440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HAT6797707.1"
                     /translation="MKKNLEATIEEIVTKITDEHGFEMVDVEYVKEAGEYYLRVYIDK
                     EEGISLNECELVSRELSPILDEKDPIKENYFLEVSSPGLDRALKKDRDFVRYQGRDVD
                     LKLYKPLNGCKQFEGELVGLTEDNNIKIIANGKEMEFNRKDVAIVRLAIKF"
     gene            51273..52427
                     /gene="nusA"
                     /locus_tag="JAM15_05445"
     CDS             51273..52427
                     /gene="nusA"
                     /locus_tag="JAM15_05445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HAT6797708.1"
                     /translation="MNHEFMEALDELVVDRGIDKEILIDTIEQALLTAYKKNFGSAQN
                     VRVEFDRDKGDIKVFSQRVVVDESDLYDTFLEIELADAREINPNYELGDIIEHEVTPK
                     NFGRIAAQTAKQVVVQRIREAEREIVYNEFIEKENEIVTGEVARANKNVVYVNLGRIE
                     GIMTQSEQIPFENYKAGQKIKFYILEVKKTNKGPQIVVSRSHPGLVKRLFEEEVPEIY
                     EGIVQIKSVAREAGSRTKMAVKSIDEKIDPIGACVGPKGLRVKNIVDELGDEKIDIIK
                     YSEDPAEFISAALSPSKVVRVDIDEDEKSALVIVPDYQLSLAIGKEGQNARLAAKLTN
                     WKIDIKSESQAEQEMLNLENSKEIEAEDVEAEFIDQEELGTSEDNFSEEE"
     gene            52434..52715
                     /locus_tag="JAM15_05450"
     CDS             52434..52715
                     /locus_tag="JAM15_05450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HAT6797709.1"
                     /translation="MILKKVKKVPQRKCIACQDRDSKKELIRIVKNKEGKIFLDPTGR
                     ANGRGAYVCKSSECLKKAIKSKALNKAFKIDVPDEVYDNLLMELEEYEK"
     gene            52705..53016
                     /locus_tag="JAM15_05455"
     CDS             52705..53016
                     /locus_tag="JAM15_05455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7ae"
                     /protein_id="HAT6797710.1"
                     /translation="MKNNKEKVLSFLGLATRAGKIVSGDDSTLLDLKKGKVNLILIAE
                     DASNNTKKLFKDKSTFRNIPYLFFSTKEEIGFAIGKSPRAVVGIKDENFSKKIIELIE
                     I"
     gene            53038..54978
                     /gene="infB"
                     /locus_tag="JAM15_05460"
     CDS             53038..54978
                     /gene="infB"
                     /locus_tag="JAM15_05460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HAT6797711.1"
                     /translation="MSKTRVYQIAEELNISNEELINKLAELDINVTDKDSVLEGEELE
                     LALEMLGEDLSQENGNVIEIDGKLTVQVLATKLDKSPSEIIMKLMKMGTMATINQEIS
                     FEIAALAAKDYGFELTVAESDDTEALEIEALMEIEEDKEEDLKPRPPVVTVMGHVDHG
                     KTSLLDAIRKTDVISGEAGGITQHIGASEVKINGHKIVFLDTPGHEAFTSMRARGAQV
                     TDIAILVVAADDGIMPQTVEAINHAKAAGVPLIVAINKIDKPGANPDKVKQELADQGL
                     LVEDWGGEVIAVPVSAKKKEGIDTLLEMVLLVAEMEELRANPNKRAVGTVIEAELDKG
                     RGPVATVLVQGGTLTVGDPIVAGVACGKVRAMINAKGKRVKTAGPSTAVEILGLSEVP
                     QGGDQFVEVPTDKIARSVAARRQQIVRDEMLKSTQRLSLDALFSQMSEGSIKDLNIVI
                     KADVQGSVQAVKQSLEKLSNEEVQVKVIHGGVGAVTESDILLAAASNAIIIGFNVRPV
                     PGAESLGEKENVDIRTYTIIYKAIEDIQAAMTGMLDPEYVDEETGKAEIREIYKISGV
                     GTVAGCYVTNGKIFRNCKVRLVRDSIIIHEGELAALKRFKDDVKEVNSGYECGMSFVN
                     YNDIKEGDIVEAYITKEVERKL"
     gene            55021..55401
                     /gene="rbfA"
                     /locus_tag="JAM15_05465"
     CDS             55021..55401
                     /gene="rbfA"
                     /locus_tag="JAM15_05465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HAT6797712.1"
                     /translation="MASYNRTRRIAEEIRKVVSTMLINGVKDPRITSMVSVTDVEVTN
                     DLRYAYVYVSILGGDEESTLTGLKSAGGYIRREVGKNIKLRYIPEIVFKLDDSIEKGM
                     YMDNLIKRVNEKNAQQNEDENYDE"
     gene            55382..56059
                     /locus_tag="JAM15_05470"
                     /pseudo
     CDS             55382..56059
                     /locus_tag="JAM15_05470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438308.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
BASE COUNT        22525 a         6049 c         9881 g        17725 t
ORIGIN      
        1 tatttttgta aagaaaaaat aaagaattta ttttctgaat acttattaat taatcaaagt
       61 taaaatgaaa aaaatataaa aaaataaagt atataagagt ataatttgac ttttatatac
      121 ttttttatat tatttttgag ttttttagga agatatttta caagttaaga aaactataag
      181 gagtgttata ttgaatataa aatagtataa tatatattat gttagataat taatatgaaa
      241 atatacaaat atataaaaag tttgtttaga gttatagtta atgtgtgtat taatttaata
      301 ctaatttatt ggaggtttaa aaatgaaata cataataaaa agagatggta caaaagaact
      361 ttttagtaaa agtaagattg aagatgctgt ctataaagct agtataaata gtgaaggtgg
      421 agtagataga gagttggcat atgatatatc aagaaaaata gctaatgact ataattctat
      481 ggaaaaatgc ttatccgtag aagaaataca agatatagtt gaagtactac ttatggaatc
      541 aaatagaaaa gatatagcaa aacactacat attatataga gaaagacgct ctgaaataag
      601 gactaaagct tgggagtttg atgaattaca aaaatcaata tggaagaaca agtatagaca
      661 taatggtgag agttttgatg aatggataaa gagaatttca aataatagtt caagaatatc
      721 aaaactaata agacaaaaaa gatttctatt tgctggaaga attttagcaa atagaggatt
      781 acagaaagaa ggaaaaaaag taacatattc taattgttat gtaatagaac caccaaaaga
      841 tagcatagaa gatatatttg atactgcaaa aaaacttgct agaactttta gttatggtgg
      901 aggagttgga attgatattt caaagctaag accaaaagga gcgaaagtta acaatgctgc
      961 aaaacatacg actggagcag tctcttttat ggaactttac agtatgacaa ctggcttaat
     1021 tggtcaaaga gggagaagag gagctcttat gatttctatg gatgtaaatc atccggagat
     1081 agaagagttt atagatataa aaacagattt ggagaaggtt actaaagcaa atatttccat
     1141 aagggtaaca gatgaattta tgcaagctgt aagggaaaaa aagttatata attgtacttt
     1201 tgaagttgaa actactggag aaaaaatagt taagatagta aatgcttatg atttatttaa
     1261 taaatttgtg aaaaataact gggattatgc agaaccaggt atattgtttt gggataaaat
     1321 aaaaacatat aattttatga gtgaagataa gaacttttgc ttttcaggag taaatccttg
     1381 tgcagaagaa ccacttccaa gtggaggaag ttgtctactt ggctcaataa acttgtcaga
     1441 gtttataata caaccatttg gtgaacatgc tacttttgat attaataaat taaaatcttg
     1501 cgttagagaa gctgtagtag ctttaaatga tgtcttagat gaggggttga acttgcatcc
     1561 attacaagaa caaagagata gtgtacataa gtatagacag ataggtttag gtgtaatggg
     1621 tatagctgat atgcttataa aaatgggaat aagatatggt tctgatgaat ctttagaact
     1681 atgtgattta attggtaaga ctatgttaaa tgaagctgtg aagcaatcag cattaattgc
     1741 taaagaatat ggaacattta gtgagtataa atatgaaaat atttctaaat ctaagttttt
     1801 tatagaaaat ctaaatgaag acactaaaga aatggttaaa aagtatgggc ttagaaattc
     1861 acaactttta accatacctc ctacaggttc tatatctaca atgataggta tcagtggtgg
     1921 aatagaacct atatttaatc tttcatatat aagaaaaact gaaagcttgc atgatgagga
     1981 tgtgtattat aaagtatata ctccaattgt taaagagtat atggacaaga aaggtattac
     2041 agatgaagaa tgtttaccag atttttttgt tactgctatg aatataggat atgaagaaag
     2101 aataaacatg caaaaagtat ggcaaaagta tattgatgct tctatatcat ctacaataaa
     2161 tatacctttt gaaactacag ttgaagatgt tttcaatata tatattaagg catgggaggc
     2221 tggtcttaaa ggagtaacaa tatttagaga tggatgtaaa aggagtggaa ttttaataaa
     2281 tgaaaaaaag gaagaaaata ataaagaaga taaaaaagaa aatagtaaaa aagaatatta
     2341 taaaaataat aaaaaagaaa aagataataa agatgaaaaa gccaaagaaa taataaataa
     2401 aaattttgaa gaagatgaaa aatttgtgtg ccctgagtgt ggaagtgaag gaattgcaca
     2461 tacaggtgga tgtagtatat gtttaaaatg tggctatagt ggatgcaatt aaactctaat
     2521 taaaaaattt taatatattt aaaaattaaa tttttaaaaa cgaaagatga gggaatggta
     2581 tgcaggataa aagtgtgagg gagattaaag aaaaaataga gactttagaa gtagaaaaat
     2641 atatggaata tatagagctg ttaagagttg atgaaagaaa atctgtacaa ggtctagcta
     2701 taaaactagc aaaaaagctg gataatatta gaaaagaaga agaaagattg gaaactataa
     2761 atatatttga gaacgaaggc tatgataaag gttatttata tattggagga attgatgagg
     2821 cgggaagagg accacttgct ggacctgttg tagcttctgt tgtagtattt aaaaaagata
     2881 ccaaaataga aggtgtaaat gactctaaga aactgagtga ggcaaaaaga gatgaacttt
     2941 ttgaagtaat aaaagaagaa gcactagatt atggaatagg tatagtaaac aatgaagaaa
     3001 tagatgaatt taatatatta aatgctacat atatggcaat gaaaaaggct ataaattgtt
     3061 taaaaaaagc accggattat ttattagttg atgcagcaac aataccaggt attgacatat
     3121 ctcaaaatcc aattgtgaaa ggagattcaa aatctatatc aatagcagca gcaagtatac
     3181 ttgctaaagt tactagggat agtataatgt accaatatga tagagtatac ccagaatatg
     3241 ggtttaaatc tcacaaagga tatggaacta aagaacacta tgaagctatt gaaaaatatg
     3301 gcataactcc tatccacaga aaaagttttt tgaaaaatat actgtaaata taatatgata
     3361 taatgtatat aatataaatt actatagtta atgggggatt aaagatggaa tataatgaat
     3421 tattaaaaag tgctagagaa aatttaaatg gaagttgtaa agtttgtaag gtttgtaatg
     3481 gggttgcttg tgcaggtgaa gtgcctggca tgggaggtaa aggaagtggt tcttctttta
     3541 tagaaaatag caagagttta gaaaaagtaa aagtaaatat gagagtaata catgatgtat
     3601 caaatcctga tacatctata gagatgtttg gaaagaaaat gagtgcacct atatttgcag
     3661 ctccagtaac aggaactact ttaaatatgg gtggaaaaat taatgaaaga gattacatag
     3721 aaccagtagt tgcaggatgt gctaatagtg gtatttatgc aatggttggt gatacggcag
     3781 tagatgcttt tttaatggaa aatttagatg tagtcaaaaa gtataatgga gctggaattg
     3841 tatttattaa accttgggat aatgaaaata ttataaaaaa gataagatta gctgaagaag
     3901 ctggtgcatt tgcagttgga gttgatatag atgcctgtgg tctagtaact ttatcattac
     3961 atggaaaacc agtacttcct aaaaatgtta aacaaataaa ggagttagta aagtctacta
     4021 aactaccatt tatattgaaa ggtataatga ctgttgaaga tgctttaatg gcagtagaag
     4081 caggtgtgta tgcaatagtt gtatcaaatc atggaggaag agtgcttgac tgtacaccag
     4141 gagcatgtga agttttacca aaaattgctg atgctgttaa aggtaaagtt acaatacttg
     4201 cagatggtgg agtgagaact ggtttagacg tactaaaaat gataggttta ggtgcagatg
     4261 cagtattaat aggaagacct tttgtgactg cttcatttgg tggtgcaact gatggtgtag
     4321 aaacttatgt aaataaactt caatcagagc taagtagttc tatgatatta actggatgtc
     4381 aaactataaa agatattgat ggaaaagtta tatacaaata aaattttata caaaaaagag
     4441 gaaaaatcat tttaatgtag aataattgta caaaggggga atttatatga gtagaaaagc
     4501 ttatgaagaa gccttagtag aattagaaaa atttattgat gaaagaaaag aaataattaa
     4561 aagtgcggag gactgtattg ataagtacat agttgacaga acgctacctt ttgattacaa
     4621 agataaatgt gtggaatggc aacaagagtt acttgatatt gcagaggcac aaattttaga
     4681 agcaaatgaa ttaagtgtat tattacaaga gaaaaaagaa cttgaagaag attaaatttt
     4741 attagctaag agtaaatcag taatatgatt tactcttagt ttttttattt gaataaaata
     4801 catctatcta attgagataa ctttattaat attagattag gcagtttaaa gtaagctaaa
     4861 gtagcatgga tgattagtat aaaaaataaa accagtttaa aaaactggtt taatttgtat
     4921 tctttgaatt taatatatgt tttttcattt cctctaatac cattgtatag gatttacatt
     4981 gagcagcagc taattctgat aaagcaaatt tttgagcttt atttaaaaac tccttatctg
     5041 tgctacacaa ttgttttgaa ctgtcttgta tcataagcat tttgattaat tttacaattt
     5101 caaaaacatc tcctgaatga aatttatctt ggtacagttt aagtctttct tttctatcaa
     5161 aaatccatac accatctgtt ttattaatag attggataaa attatcaaca tcatttccat
     5221 ccataactgg acgtatgcca attctatctg catttagaac tggaatcgaa attttaaggt
     5281 tactattaaa aatgacactt aattcatagt atttttgcat ctcatgattt attttctttg
     5341 ttacaatatc atttacagag caggctccct cttttggata cattacactt tcaccaattt
     5401 tatacatatg ctagttatac ctccaaattg aattttagat attgcaactt aggtacaatg
     5461 ctttaattat ctaatgatta atattataac ataaaaaact tgacaagtca aaaatattaa
     5521 tatataatat taagtttagg attggtgatg tgtgaaacta aagagaaaaa tataagataa
     5581 aataatttaa tatgttgaaa tattctttta caattatata aaaatagata ctaattatat
     5641 ttaataatta ttagttttta gcaaaatctc ttagtttaag acttcctgca gttacaaata
     5701 taattccaat taatattaga gctattatat ttattaaaat actaccattg tttttaatag
     5761 catctatagt ccaataaaat ggtgtgaact ttgaaagatt agtcataaag gataatttat
     5821 ccattgatgg tattagacta gagatagata tagctagacc tattaaagaa taaaatgtag
     5881 atataagact tatagaactt tcatttttaa atactctagc tacccaaaat acaaatccag
     5941 tggaaacaaa actatttgct agtacaatca tcaatacatt cagactcaaa ttaaagtctt
     6001 ctataattga aaaacataat agagcaaaag tgtatacaat tgattgaata aaaaatagtc
     6061 ctaaaaatat actgaaaatt atttttatat ctttattatc tgtagagata agtcttttta
     6121 gcacatttga tttttttaat gtaaataaat cagaagcaag atgtgccgca ttaatataca
     6181 taaaatagca tatcaagaag actactaaaa atgaaccttt attcttatct ggtttgttat
     6241 caattatatt tgtctttgtc aatttatcat ctatattttt atccactttc aattttaacg
     6301 atttagtaat aaaagattct atttgtgatt ctgcccaaag actaccacca ccattttcaa
     6361 ttttaaagca tttaactaca ggtcgttgta atttatctat actatttgaa aaatttttat
     6421 ctaaaacgaa tacagcagaa accttattat tttttaatag attcatagcc ttatcttgtt
     6481 catttaatct aaatgaattt tcttttaatt tagaactatt tattaactta tgttcatact
     6541 ttcctgaaga gtcagataca attgctactg gagaaaagta cattgattga tttcccgagt
     6601 tgttgataaa aaaattaagt gaaaaaatta gtataatagg aagcataacc atattaatta
     6661 aaagagtatg attttttaga tatcttttta tatttgcaat agttaatcta atcattatta
     6721 aacctccctc catttatatt tttcctttac aatagcaagt gcaattaata ttgtagagat
     6781 aattaaacat gtgaaaatta aatttcctat tgaatctatg gttttaaatg tttcataatt
     6841 actaaacaat tctcctatta aataggtagg agataaactt gtaagcttag taaatgtatc
     6901 acttatcata ctgaagatac ctccaaaaat tgtctgtaaa aagagtaatg cataaactat
     6961 tgctgtaccg tattttttac taaaaaagct ggttacaaag gtagatattg aagtcataaa
     7021 ataagatgat aaagcacaaa gtaggagcaa tatggcaaaa ttacctttaa atgttattcc
     7081 aagtattcta aagaataaaa catataataa taagaatata aatgaataaa tccataaacc
     7141 tacaaagtca taaattaaga attgtactct agttataggc atagaataaa gtctttttga
     7201 aagtcccttt gattcactta tataatttga taaaatattg ttcattataa aaattattac
     7261 aagaaatcct agtgaaacta aagcaaagta ttcataagag ctctgtttaa cattgttatt
     7321 tattatagaa gtatcaatag aatttttatt aaataattta gaaaaatctt ctgaacttat
     7381 tttctgagaa ttatttaaat aaaatttttc atggtaagta tctaatatat cttgaagcaa
     7441 tattgcgata tcatcacgag ttccaagttt ttctatgttt agagtatttg atttttcatt
     7501 taataaacta ctctcatagc ctttaggtat agtaagcttt aattctgcct tagaatcatc
     7561 ttttttaact gttaatatat aagataaatc atttttcaaa tactttgtca aatcatttga
     7621 taatcttgtg ttatctttgt catatataac aatgggggta gattctgttt ttatagggtt
     7681 ttgaaacatg ctttctgtaa ccatcccaag aaaccaagat aaaatcagag gcaaagctaa
     7741 aaaatatatt aaattaagta taaaggagct ttttaaactc tttagcatag tttttacact
     7801 catgtataat ttcataaaat cacctccatt agtcccttaa attttttcct gttagattta
     7861 aaaatacgtc ttctaggcta ggttcttcat aagaaatttt cattattttt gaattgtttt
     7921 tgtcaataac agagagtata tctgtaagtt gtaatttttt atctatatcc aattctaata
     7981 atgaattatt ttctaaaaca gatataacac ctttagtatt ttttaaatca aagataagtt
     8041 gggcatttat attttttatt tccataatta attttgtatt tgtagatacg agtgatttta
     8101 aataatcatt atctccaaaa gcaatttctt taccttcatc cataataaaa attttagaac
     8161 aaaggtgttc aacttcttcc atataatggg aagtatatat tacagtagtt tcatgttttt
     8221 tagatatatc ttttataaaa ttgaaaatat gatttcttga ttgggggtct acacctacag
     8281 ttggttcatc caatattaat attttaggat gatttaagag tgctattcca atatttaatc
     8341 tcctttgcat accaccagat aattttttga cctttttctt tttgacttca gtaagacctg
     8401 taacttctaa tgcttcaatg attctttctt taagtagttt tccctttaaa ccgtagaaag
     8461 ctccaaagta ctctaagtta tcaaaaggag taagagtttc tataattgct aattcttgtg
     8521 gaactaaccc tattatagac tttgctttta tataatcttt tgataaatct aaaccattga
     8581 tttgaatact accactattt ggtaacataa gatttgtaat tatatttata agtgtagatt
     8641 tacctgcacc atttgggcca ataagtccaa atatctcacc ttttttaaca gaaaagctga
     8701 tgttatcaag tactaattta tcattaaatc tttttgttat attatttact ctgactatat
     8761 ccatagtaat ccctccaaaa taattttgta taagttaaaa agctataata ttataataaa
     8821 gaattgtgaa ttataattct attactataa gtcactaaaa aaagtgactt aagtcacttt
     8881 atatttttag atttattcta ttacaatttt atttttgaaa gcaaagattg ctagttgagt
     8941 tctgtcacga agttctagtt tagctaaaat attagttatg ttattcttta ttgtaccttc
     9001 agataagaat agttcttgac ttatttcttt attattaagt ccatttgcaa ttagtctaat
     9061 tatagatatt tctttttctg ttaaattgta catgtcataa agatgctctt gtttaaccgt
     9121 tttttcagag gtcatgattt tttcagctac acttttatca agcacaatat tgccaaaaaa
     9181 tgaagaacga atcccttcat gcaatacttc atcagagcta tcttttaaaa ggtatcctga
     9241 agcaccaaac ttcatagcat cttttatata ttcatcatca ttaaaagttg ttaaaattaa
     9301 taatgttata gaattattat attcctttat aagccttgta cctagaaccc catcacatac
     9361 tttcattcgt atatccataa gaactatgtc tacatcattc attttacaaa attctaaagc
     9421 ttcatatcca ttagaagcat ctcctacaat ttctaaatca ttataagatg ataatataat
     9481 tttaagacct tttctaatta atttttcgtc atctactata agaactttaa ttttattcaa
     9541 aaaaatcacc ccctgaaaat ttaggaaaag aagctctaat tgtgaaacca ttattagaat
     9601 tatcaaattc aactttacca tttaattcat atattctctc attgatacta ttaagtccat
     9661 ttcctttttt tatattgcca catcctatac cattatcact aatagtaatt ataagatttg
     9721 aagtattgaa tgtaataaaa attctgattt cagttgcctt tccatgccta gatgagttgg
     9781 aaagggattc ctgtataagt ctatataaag ctatagattg atttctggat aagttccaag
     9841 tattttttga aatagttaat ttaacattaa tatttgtaag cttaataaag cttttaacta
     9901 attctttgat tttaaataaa ctttggtaat tttcatattc aacaggtttt aactcagata
     9961 tagcccttct tacatcttga aaactttcag ttacaaattc tctaagttca tgtactaagt
    10021 cataaattag aggtttgtct tttaagagtt tttctatagc atttaattgt attattgttg
    10081 tagaaagaga atgtcctaca ctatcatgta tttctcttga tattcgattt ctttctttta
    10141 aaattgctaa ttcttctata gaacttgcat aagtttccaa atcagcatta acttttttta
    10201 attcatcttt agaaattcta agcttatcat aaagattttg actgtataat tttgataaat
    10261 tctcattttc tatatatata gaaagtacag ttataattag caatatagag cttgactcta
    10321 gtgccaaata tatattttta tctaaactaa taacaagaga agatattata acaaaagaga
    10381 acaatatgta cttatatttt tcctttatta aaaatgatat atctaatatt aaaggaacaa
    10441 agtaaatcga attaaaagtt tttgtataat tacaaagtat aaaaattaat ataagttcta
    10501 aaaagtaaga aataagtata aatttattct catttgataa agaaaaaaat ctaacttgat
    10561 tatttattat aattagaaat aatattatca tagttatgac cggatacaat gtattttcaa
    10621 catttttcaa atagcttaca actaatataa ataaagataa atatcgtata aaagcaacta
    10681 atttttctct gttcattaaa ggcactcctc caaaaaaata aacttttcct atgaaaacta
    10741 gaataatatc ataaaagaat aaagtcaata gaagtattta ttaatattga tggaaataaa
    10801 atcaatccaa aaacttgaat agtaaaattg tatactgacc ataatttaaa agtgaaaatt
    10861 taatgtattg gagtgaataa tgaataataa agaaaaaggt gattttggag aaaaagtagc
    10921 agttaattat ttgctatcaa aaggagcaaa gatactagaa aaaaattaca gattaaagat
    10981 aggggaaata gatataatag caaaaatgga agatgaaatt atatttgtgg aggtgaaatc
    11041 aaggtctaac ataaagtttg gctacccttg cgaatctgta agcttcaaaa aaagaaaaaa
    11101 gataattgga gttgcaagtt attatattat aaaaaataac ttaaataaca ctcccataag
    11161 atttgatgtt atagaggtat atttattaga aaaaagaata aatcacataa tgaatgcttt
    11221 ttaaaaaaga taatgttttt ggaaaggatt aaatatgtta agtattatta attcaagcaa
    11281 cttagtagga atcgacagct ttttagttaa ggttgaagta gatgtaagca atggaatacc
    11341 tagttttaat attgttggtc ttccaggcaa agaaattaaa gaagcaagag aaagagtaaa
    11401 gtcagcaatt cttaatagtg gatataaatt tccaagcacg agaatagttg taaatttatc
    11461 accagcagat ataaaaaaag aaggagcttt tttagattta tctataagta taggcctttt
    11521 aagagagtta ataaaaaaag atgaaaatta cataagagaa agtatgttta taggagaatt
    11581 atcattagat ggaaaaataa gaaaagtaag agggatattg cccataatta tgggtgcaaa
    11641 aactcagaac ataaaacgta tttttatacc aattgagaac ataaaagaaa gtctatttgt
    11701 agatgaaatt gatataattc ctattaaaag tttaaaagaa tgtgtcgatt ttttaaacga
    11761 agagataaaa gtcgataaag taaggataat gtcttttttg gatgataagt caagaaaaga
    11821 gaacgaagaa ttagaaaaag ataatagtta tatagattgc aaatatacta agattaataa
    11881 tgaagaaagt aaatatgatg aagactttaa agatgtaaaa ggaaattatt ttgtaaagag
    11941 gagtgcagaa attgctgctg ctggaaatca taatatgttt atgattggac ctccaggctc
    12001 aggaaaaact atgattgcaa aaagagtaag gacaatttta ccagatataa gtatagaaga
    12061 aatgatagaa gtaagtaagg tctatagtat attgggtatg ataaatgaaa ctaaaggaat
    12121 aattgataaa agacctttta gagcacctca tcatacaact acaaagcaat ctttaattgg
    12181 aggaggaatg gatgcaagac ctggagaaat tgctttagca catagaggta tcttattttt
    12241 agatgagata gccgaatttg atagaaaaat acttgagact ttaagacaac ctatagaaga
    12301 tggatatgta aatatatcca gagtaaagta cagtgcaaaa tatccttgta gagtactgtt
    12361 agttgcagct atgaatccat gtccatgtgg ttattatatg tcagagacag agtgtagatg
    12421 tagaagtaac gaaattgata gatacataaa taaaatatca ggtccattgt tagataggtt
    12481 tgatattttt gtagaagtta attctataaa atattcagat tttaattctt taaaacaaga
    12541 agaaagctct caaaaaataa agagaagagt agaaaatgct agaaaaatac agataaatag
    12601 atttaagaag gataatataa aaaataatag tgaaattaaa gcttacaatt tatttaaata
    12661 ttgtaaactg gaaaaagaag cttcaaaaac ggctgagatg atatttaata aatacaacct
    12721 aagcagtaga agttatacaa aacttttaaa aatggcaaga acaatagcag atttagaaga
    12781 aagagacttg ataaattcac agtgtattat agaagctttt tcatttagaa aggcttatta
    12841 tagttatttt aaatagtttt ttgaggtgga ttttatggaa aaaagagata cttatttatg
    12901 gttaaaatca attggtggaa taacaacaaa aacaattgaa ataatagaaa atgaaatagt
    12961 aaatattgaa gatatatttg atttttctga aaaagaaata tataatttaa aaaatataag
    13021 cttgaatatt agaaaaaata tagtaaaata tagaggtcac gcttatttag aaaatataaa
    13081 agaactactt tacaaaaaag cgattaaata tatttgtaaa tatgataaag aatatcctga
    13141 aaatttaaag aatatataca acgctccaaa gttattattc tacaaaggtg acataggttt
    13201 agttaataat aattttaata tagctatagt aggttcaaga aaacctacag cctatggaat
    13261 taattgtgca aaaacaataa gttgtcaact atcccaatat ggagttaata tagtaagtgg
    13321 attagctata ggaatagatg catactcgca cataggttgt atgagtggaa aatctaaaac
    13381 tatagcagta cttggttcag gagtagacaa tcctcttcca aaacaaaatt tacatttatc
    13441 aaataaaata ttagaaaatg ggggattatt attatcagag tataatatta actcgacagt
    13501 agccccgtac catttttcta atagaaatag aattatcagt ggtttaagtg atggagtagt
    13561 tgttgtagaa gcagcaataa aaagtggtgc actaatcaca gtagattttg ctcttgaaca
    13621 tggaaaaaat gtttttgcaa tacctggtaa tataaattct caaatgagta gaggttgtca
    13681 taaaattata aaagaaggtg caaaattaat tgaaaatata gatgatattt taaatgaata
    13741 taacatattt aatattattg ataaaaaaat aaatcaaaaa tatgataata taagtctaaa
    13801 tgccaagtct aagcaaataa ttgaagctat aaaaagagaa ggaaacttgc atatagatag
    13861 tatttgtgat tatactggta tagaaataaa gtatgtaaat tcaataatca atgaattagt
    13921 actaaatgag ttagtagtag aaatgaataa taaaacgtac agtttaaatg tataaattaa
    13981 gattaggtag tgggggtgta tggttttatg gccaaaacat tagtcatcgt agaatcgcct
    14041 gcaaaagcta aaactataga aaaattttta gggaaaagtc attacacagt taaagcatca
    14101 gttggtcatg tcagagattt acctaaaagt aaattaggtg tagatataga aaataatttt
    14161 gaacctcaat atataaatat aagaggaaaa ggcgatgtaa taaaagaatt aaaaaaagaa
    14221 gctaaaaaat ctaaacaagt atatctagca actgaccctg atagagaagg tgaagctata
    14281 tcatggcatt tagctcatat actaaattta gatgaatctg aggattgtag aatagagttt
    14341 aatgagataa ctaaggatgc aattaaaaaa gcaattaaac atcctagaaa tattgatata
    14401 aatttggttg atgcacaaca ggcaagaaga gtgctagaca gacttttagg ttatcaaata
    14461 agtcctatat tatggcaaaa ggttagaaaa ggtcttagtg caggtagagt gcaatctgtt
    14521 acaacaaagt taatttgtga tagagaaaaa gaaataaagg catttattcc aaaagaatac
    14581 tggacaatag atgttgaggc taagacagta aaagacaaag atataacttt gaaattttat
    14641 ggtaaaaatg atgaaaagat tgaattagaa aatgaagaag ctgtaaatga aatactaaaa
    14701 gaaatggaag gtaaagattt aaaggttgag aagatagaat ctaaatcaag acgtaaatca
    14761 gctccaaaac catttacaac aagtatgctt caacaagaag gagcaaataa gttatttttt
    14821 actactaaaa aaacaatgat gatagcacaa gaattatatg aaggtatcga catagaaggt
    14881 gaaggtactg ttggtcttat atcatatata agaactgact ctaaaagaat atctgatgaa
    14941 gcaaaagaaa aagctaaggg ctatatcgta aacaatttag gagaaaacta ctataaaaac
    15001 actggtgata aaaaagaaaa aaaggatact aaaaaggttc aagatgccca tgaggcaata
    15061 agaccaacct cagttgatag aactcctgag agtataaaag cctcattgag caaagaccag
    15121 tacaagttat acaatttaat ttggagaaga tttgtagcta gtcaaatgga agattcagtg
    15181 tttgatatac taaatgtaga atgtaaaata ggcgatattg tatttaaggc aactggttca
    15241 aaaatgaaat ttgatggtta taccaaggta tataattttt cagaaagaga agacaaaatt
    15301 ttaccaagta tagaaaaagg agatatatta aatatagaaa atatattgcc agaccaacat
    15361 tttacacaac caccagcaag atatacagaa gctagtttag taaaaacact agaagaacta
    15421 ggtataggta gaccaagtac gtatgctcca acaatagcta ctatactgaa tagagagtat
    15481 gttgaaaagc aaggaacaag tctatgtcca acagaacttg gaataatagt tactgatatt
    15541 ttggaaaata atttccataa atttatagat gtagatttta ctgctgatat ggaaagtaaa
    15601 cttgatgtta tagaagaagg caatacagat tggaaaaaga ttgtatcaga atcatatgca
    15661 ccacttaaag aggctattga agaagctctt gaaaatatag aaaaagtaaa tatggatgaa
    15721 gaaactgatg agatttgcga gaactgtggg tctaatatgg ttatcaaata tggtagattt
    15781 ggaaagttta tggcttgtaa aaactatccc gattgtaaaa caactagacc aattatgaat
    15841 aaaattggtg ttaaatgtcc aaaatgtgaa gaaggagata ttatacttag aaaatctaaa
    15901 agaggtaaag ctttttatgg gtgttctaat tatccaaact gtgactttgt agcttggaat
    15961 aagccaacag gagagttttg tgagaagtgt ggttcatata tggttgaaaa agtgactaaa
    16021 tctgaaacaa aaacagtgtg ttctaataaa gaatgtaata aagagacaaa agagcataat
    16081 gacggaaaag agtgaaaatt gaaaaaaatc acataattct cttgaaaaag gttccaatct
    16141 atgataatct ttcaagtgta aacaactaat agaaaaataa attttcatta aatgtgaaaa
    16201 taatattaga aaatataaaa ggttattaaa aggcctaaat ttcatgagga gatgattaaa
    16261 tggcaagtga agtgttacaa aaaacaagga aaataaataa aacattacaa acaagtggtg
    16321 gaagcagtgt ctcttttgat ttactggccg gagcattggg cgacgtttta agttctaatg
    16381 tttatgtagt aagtgcaaaa ggtaaagtac taggtcttca tttaaatgat gttcaagaca
    16441 gttcagttat agaagatgag tatactaagc aaaagaaatt ttcagatgaa tatactcaaa
    16501 atgtgttaaa aattgatgaa acattagaaa atttaaatgg tgagaagata ttagaaatct
    16561 ttcctgaaga acatggaaga ttacaaaaat atactacagt agttccaata ttaggaagtg
    16621 gtcaaagatt aggaacattg gtactttcaa gatattcaaa ttcattcaat gatgatgatt
    16681 tagtaatagc tgaatacagt gcaactgttg ttggtcttga aatattaaga gcaataggtg
    16741 aagaattaga agaagaaatg agaaagaaag ctgtagttca aatggcaata ggcactctgt
    16801 cctactccga gcttgaagca gttgaacata tttttgctga attggatgga aaagaaggtc
    16861 tacttgtagc aagtaagata gctgatagag ttggtataac taggtctgta atagtaaatg
    16921 cacttagaaa atttgagagt gcaggtgtga tagaatcaag atcattaggt atgaaaggta
    16981 ctcatataag aatacttaat gataaactta cagatgaatt aaaaaaatta aaaaacaatc
    17041 aataatctat attttatagg tttatattag aaaaggtatc tatttcaaat agataccttt
    17101 tttagacgaa ttattaaggt aatgataagt atattaaaaa ggagtgagaa aatgccttta
    17161 gcagataaaa taagaccaaa aacaatgaat gatgtaatag gtcaaagtca tataataggt
    17221 aatggaaaaa tattgtctaa gatattacaa tctaattttt taccaaatat gatatttttt
    17281 ggtcctcctg gtgttggtaa aactacagtg gcggaaataa tagcagaaag aagcaataaa
    17341 agcttctata aaataaatgc tactaattca tctttagaag atataaaaaa ggtgatatca
    17401 gagcttggaa gtataaataa tgtaaatgga gtcctattat atatagatga aatacaaagt
    17461 tttaataaaa aacagcaaca atcaatatta gaatttatgg aaaatgggag tataactttg
    17521 attgctagca ctacagaaaa tccatatcat tatgtatata aagctctttt aagtaggtct
    17581 actgtatttg aatttaaacc tttagaaaaa cttgatatag aaaaaggact gaaaagagct
    17641 gttgaagtat taaatgaaga tagctatatg gatattgagt gtaataatga tgctattgaa
    17701 gatatagcaa ttctttctga tggagatatg agaagagcct taaatatttt ggaagtggta
    17761 gtctattcaa ctaaaccaaa taaggataat ataacttata tagattcaga tgtaataagg
    17821 gcatctacat ttaataaaat tataaactat gacaaaaatg gtgatagtca ttatgatatt
    17881 ttaagtgcat ttcaaaaatc tataagagga agtgacccac aggcatctat acactatcta
    17941 gcaagactta taaaaggtgg ggatttgata agtatatgta ggagactttt agtaatagct
    18001 agtgaagata taggtttagc ttatccaaat gctattgtaa ttgtaaaggc atgtgtagac
    18061 tcagctatgc aacttggatt tccagaagcg aaaataccat tagcagaagc tactattctt
    18121 ttggctacat ctccaaagtc taattctgca tgtatagcaa taatgaaagc tatggatgaa
    18181 ctggataaag agtttgttaa ggatatacca aatagtataa aggatgctca ctattctggt
    18241 tctaaagaaa taggtagggg ttgtggatac aaatatcctc ataattttaa aaatcattat
    18301 gtaaagcaac agtatttacc agatagcata aaagatagta tttattacat accacaagaa
    18361 aataaaactg agaaaaatat aaaaaaatat ttagaatatc taaatagtga tttttagact
    18421 gaactttatg tatcgggggt agatattatg attataaaac ttaactcaac ttatcacagt
    18481 agagttatga aatacttaaa aaaagaacct gagtacaatt tgtttataat aggggatatt
    18541 gaaagatatg gatatggaaa taatttttta aatatatggg cagatgtggg tgaacatggt
    18601 gaaataaagg caatattact taaatatttt gaatttatga tgttttattc tgatggagag
    18661 tatgatgttg aaggttttta taatctactt cgtaatacta attacgaaga aatatctggg
    18721 aaaatatgtg ctgtagatac tttagcaaag agattaggac ttaataattt aaaggtagtt
    18781 gatttttgca aacttcaaac taaaaagttt ttgatagata ataattgtaa tgcaaaggtt
    18841 aagagaatta ggcttggaaa tctaaaaaag acagtgaaac tttatgactt aatagatgaa
    18901 tttcacagta caactttaga gaatttaaaa aatggactaa ggacaggtag aggatattgt
    18961 atagagatta acaaacaggt ggtgtcaatg gcaaagagta cttcagaaaa taggactcat
    19021 gcaatgataa ttggagtagg aacacatcct aaatatagag ctaaaggact tgctacaaaa
    19081 tgcctaatta aactatgttc agagttactg agagaaaaca aaattccttg tttgttttat
    19141 gataatgaag aggctggaaa gatatataaa aaactaggat ttgaaaacat tggaaaatgg
    19201 ggaatttatt caaaataaaa aattaaaatt aatcttgaca aaattagtag ggtataataa
    19261 aattatcttg aaagtaattc ctactaaaac agtatgaatt agatttctat atagaggtga
    19321 taatatatga agttgtctac taaaggtaga tatggactaa aagcaatgtt tgaattagca
    19381 ttaaatcaag acaatggacc agtatcatta aaatttattg ctaagaagca aaaaatatca
    19441 gatcagtact tagaacaaat attttcatct ttaaaaaaat cgggtctagt aaaaagtgtg
    19501 agaggtgctc aaggaggtta tttgctttca aagaatgctg aagacataac agtaggagat
    19561 atacttgtag tattagaagg accagttgca ttatctgact gtgtactaga tgaagatgta
    19621 tgtgaaaact caaacatgtg tgtaacaaaa atagtttggg aaaagatgaa aaagggtata
    19681 gaagatgtta tagattcaat tactcttaaa gatatgataa atgactataa caaaaataaa
    19741 ttagaaaatg atataacaaa tattaaaaaa tagatttgga gatgaatgta atggaaaaaa
    19801 gaagattgta tatggattat tctgcaacaa cacctattaa aaaagaagta ttggatgcaa
    19861 tgatgccata cctaacagat tattttggta atgcatctag ttttcacaca ttcggaagag
    19921 aagcaaaaga tgctttggat aaagcaagag aacaagtagc agcccttata aatgctgaac
    19981 ctagtgaaat atattttaca gcaggtggtt cagaaagtga taactggaca ctagagggtg
    20041 tagcttatgc taataaaaac aaaggtaatc atataataac ttcaaaaata gagcaccatg
    20101 caatacttca tacatgtgaa tacttagcaa aacatcatgg atttgaaata acttatttag
    20161 atgttgatag cgaaggaaaa gtagacttaa agcaactaga agattcaata aaagatacta
    20221 ctatacttat aagtataatg tttgcaaata atgaaatagg aactatacag cctattaaag
    20281 aaatatccga aatagctaaa aaacataaga tattattcca cactgatgca gtacaagcta
    20341 caggtaatat tccagtagat gttaaagaat taggaataga tttgatgagt atgtcttcac
    20401 ataaaatata tggaccaaaa ggtgtaggag ctttatacat aagaaaaggt gtaagacttc
    20461 ataactttgt ccatggtgga gcacaagaaa aaagcaaaag agctggtaca gaaaatatac
    20521 ctgcaatagt tggatatgga aaagcagcag aattagctaa ggaaaatatg caaaatcatg
    20581 tagaaacttt aactcgtctt agaaataagt taatagatgg tgtgttagaa agaatacctt
    20641 acacaagagt aaatggtagc ttagaaaata gattgccagg aaatgcaaac tttgcattcc
    20701 aatttataga aggtgaagga atacttttat tattagatat gttaggaatt gctggttcaa
    20761 gtggttctgc atgtacttct ggttcattag acccttcaca tgtacttctt gcaataggtt
    20821 taccacatga aatagcacat ggttcattaa gacttacagt tggagatttt acaacagatg
    20881 atgatataga ttatatacta gagaacttac caaaagtaat agaaagactt agaagcatgt
    20941 caccacttta tgatgatgcg aagaaacaag gtttagtaaa atagacagaa agataaagca
    21001 taaaaaatag acataaattg agtaggagga aaagataatg caatatagtg ataaagttat
    21061 ggaacatttt atgaatccaa gaaatatggg agaaattgat aatgcaagtg gtgtaggtga
    21121 agttggaaac cctacatgtg gagatataat gaagatattt ttagacatag atggagatgt
    21181 aataaaggat gttaagttta aaacatttgg ctgtggttca gctatagcaa gttcttctat
    21241 ggcaactgaa atgataaaag gaaaaactat aaaagatgca ttagaactta caaataaagc
    21301 tgttgcagaa gctttggatg gtttaccacc agtaaagatg cattgttcag ttttagctga
    21361 acaagctgta aaagcagctc ttatagatta tgctcaaaag aacaatatcc atataccaga
    21421 attggatgga tatgttatag atgatgctca tgaccatgat gttgaagaag aagaataaaa
    21481 ataagtgatt gtgttatgag aagtttacaa tgattaaaaa gaagtactaa tgatataatt
    21541 aggacataaa aaatagctgt ttttaaaatg gctatttttt attgcctaaa ttaagtattt
    21601 taacttgatt tagaggttaa ttagttaaca aaataatcca taagattcaa ataataaaga
    21661 tgattatttt tttagaaaat agaacaagct atattttaaa taagtacaat acttgctcta
    21721 tatggtataa taataagtaa tgcaaaagat gaggtgaaat ttgtttatga ataaaaaagt
    21781 aatgataggt atgagtggag gagttgatag ctctgtagct gcatatcttt taaaacaaca
    21841 aggatatgat gtcattggtg ttactatgaa gttgtggcaa gatgatgatg ttgttgaaat
    21901 tgaaggtggt tgttgttctt tatctgctgt tgaagatgct agaagggtag caaataaaat
    21961 aggtatacca ttttatgttt taaattttag agaagtgttt aaagaaaaag taatagatta
    22021 ttttatagat gaatatttgg aaggaaaaac tcctaatccc tgtatagctt gtaataaaca
    22081 tataaaattt gatgattttt ataagaaggc tagacaaata ggttgtgatt atgtagctac
    22141 aggtcactat gcaaagatag aaaaggatga aagtacagga agatatttgc taaaaaaatc
    22201 tgttacagat aaaaaagacc aaacttatgc actttataat cttacacaag agcaactaga
    22261 gcatacttta ttgccaatag gtgactatga aaaagataga gtaagagaaa ttgctaagga
    22321 aatggggatg gcagtataca ataagcctga tagtcaagaa atttgttttg ttaaagataa
    22381 tgactatgca aattatgtaa aaaaacattc taaaaagcgt attgaagaag gtttttttgt
    22441 agatactaaa ggcaatatac ttggaaaaca taagggtata ttatattata ctataggcca
    22501 aagaaaaggg cttggaatta cttttggaaa accaatgttt gtaatagaca taaatccaat
    22561 aaataatacc atagttcttg gagacaatga agatttattt aaaaaggaac ttattgctaa
    22621 agatgttaac tttatatcaa tagatacgtt agaagaaccc ttaagagttc aagctaaaat
    22681 aagatattca gcaaaaccat caccagctac tattcataga gtaggagaag atactattaa
    22741 aatagttttt gatgaagctc aaagagctat tactaaaggt caatctgtag taatgtatga
    22801 tggagacatt gtagtaggtg gaggtataat cgagaaaagt ttataaaaac atctaaaaaa
    22861 ttaaaaaaat aaacaataaa gtatattaag agtaaataaa gtttataaaa taaatttatt
    22921 gtatatgaaa atatagtatt gattaatttt gtaaaattta gtaatataat tagtatatta
    22981 ttaattaaaa aacaaataca gtgataagga atagtaaaat atttgatgtc ttacagagag
    23041 agggaaatgc tggaagccct tagaatatga tatttgaagc agccttttag tagcaatctt
    23101 gaacaattta tcttttataa gaagatttaa gtagagattg acggtagtta cgttatagct
    23161 aaggttttcc gaagatatca tactttgtat gataattagg gtggtaccgc gattgtcctc
    23221 gcccctataa atttatttat agggacgagg ttttttattt aaacgaaaaa ataaaattta
    23281 ttaggaggaa catgatatgg aaaagatggg attaaatgaa ataagaagta agtttttaga
    23341 attttttgag tcaaaaggtc attatgtagc aaatagttat tctttagtac caaacaatga
    23401 taagagtttg ttacttataa actcaggtat ggcacctttg aaaaactact tttcaggagt
    23461 agaagtacct ccaagtgtga gaatgtgtac atctcaaaaa tgtataagaa caggagatat
    23521 agaaaatgta ggtataactg caagacatgc tacattcttt gaaatgatgg gtaacttctc
    23581 atttggagat tactttaaaa gagagtcaat caaatgggga tgggaatttg ttacagaatg
    23641 gctaaatata ccagaagata agatatgggt gactgtatat gaagaagatg atgattctta
    23701 tgatatatgg gcaaaagaaa tgaatttccc agaagaaaga atggttagac ttggaaaaga
    23761 tgataatttc tgggaaatag gtacaggtcc ttgtggtcct tgttcagaaa tatattttga
    23821 tagaggagaa gaatatggat gtgacaatcc agactgtaaa ccaggctgtg attgtgatag
    23881 gtatttagaa ttttggaacc atgtatttac tcaatttgat agagatgaag aaggaaatta
    23941 tagtctatta gaaaacaaga atatagatac aggtatgggt cttgaaagaa tgggatgtat
    24001 tatgcaaggc gtagacacta tctttgaagt tgatacaatt aaatctatac tagaagcagt
    24061 tgagaagtta acaggagtaa aatatggaga gaatccaaaa aatgatatat caataagaat
    24121 aataactgac cacataagag ctgtaacatt cttagttagt gatggagtgc ttccatcaaa
    24181 tgaaggaaga ggatatgttc ttagaagact ccttagacgt gctgctcgtc atggtaagtt
    24241 attaggagta aaagaattat ttttacagaa actaatagat gaagttataa aagtaaatga
    24301 taaagcatat ccagttttag ttgaaaaaga aagttatatt aaaaaagtag ttggaataga
    24361 agaagaaaaa ttcaatgaaa ctatagacca aggaacagaa atattgaact cttatataga
    24421 agtattaaaa aatgaaggaa agactgtcct aagtggtcaa gaagctttta aactatatga
    24481 tacttatggc ttccctatag acttaactaa agaaatatta gaagaagaac atctatctgt
    24541 agatgaagaa gcttttaatg aagaaatgga aaagcaaaaa gaaagagcta gaaatgctag
    24601 aggaaatatg gatggagaaa gttggaagga agaccctcta tcaaaattag aatctacagt
    24661 tgacagtaca tttaatgggt atagtgaaat ttatggtgaa ggaactattg aagctatagt
    24721 taaagatgat gagctagttc aaagtgcaga agaaggcgat aaggtatcta tagtactaga
    24781 taacactact ttctatcctg aaggtggagg acaagttgga gattgtggat tgataactaa
    24841 tgaaaactta gttttagaag tattaaatac taaaaaaggt gctaataata gtataaaaca
    24901 tataggtata ataaaatcag gaagaataag taatggggac aaagtaaaga cactcgtaga
    24961 tagagaaact agaatgtcag ctgcaagaaa tcacagtgct acacatttac ttcataaggc
    25021 attaagagaa gtattaggag aacatgttaa tcaagctggt tctttagtaa ctccagaaag
    25081 acttagattt gatattactc actttgaagc gatatcaaat gaagaattaa aagtaataga
    25141 agaaaaagta aataatgtta ttttatcatc tttagacata aaatgtgata ttatgaatat
    25201 aaaggaagct aaagaaaaag gagctacagc actatttggt gaaaaatatg gtgatgaggt
    25261 aagagtagtt tctatgggag attattctac agaactttgt ggaggaactc acttgacaaa
    25321 tacttctcaa gtaggaatgt tcaaaatatt atctgaaggt ggagtagcag caggtgtaag
    25381 aagaatagaa gcaataacag gaaaagctgt ttatgaatac ctaaaagaaa gagatggaat
    25441 tatctctgaa gtttgtgtaa acttaaaatc taaagaagat aatttaattc aaagaataag
    25501 ttctttatta gaagaaaata aaaacttatc taaagaattg catgatatga aagctaagat
    25561 gagtttacaa tcagttgatt ctatttttga ttctaaagtt gaagtaaatg gagttaattt
    25621 gataactaat aaatttgaag gtatggatat ggatacacta agagaaacag cagataatct
    25681 aagagataag cttggttctg gtgtagtagt acttgcaaat gtagtagatg ataaagttaa
    25741 ctttgtagtt actgccacta aagatgtatt agataaggga atacattcag gtaatattgt
    25801 tagagaagtt gcaaaaatag ctggaggaaa aggtggagga agacctaata tggcacaagc
    25861 aggagctagt gatgtatcta aggttgacca agctttaagc tatgcaagtg aggttattaa
    25921 gacacaagtt aaataacatt cactcaagga ggtttttagt ttggaaaaag atttagacta
    25981 cactatgaaa tttgaaggaa taccagaaga taggatgagt gtaggagata ctattgattt
    26041 tgtatataaa gcattagttg aaaaaggata taaccctata aatcaaatta tagggtatct
    26101 cctttctggt gattctagct atataactag tcataaaaat gcaagagcta taattaaaaa
    26161 atttgaaaga gatgagatac ttgaagaagt aatcacgcac tatctgaata gaaagtaggt
    26221 caaataaatg agaaaaaaga ttatgtcgtt gtttgcaata gtcattatga tttttgtatc
    26281 aactgctagc tatggttttg ctgaagaaaa aggcaaggtc atatttattg atatgaatag
    26341 gaccaatctt ggaagtatga tgaatattcc aatcttgaaa aatgagatag aaaagagagg
    26401 ctatgtagct ctcatgaata taagagggga tcaaggtact gatgatagaa ggtcttatgc
    26461 aagtatgggt gcaggaacaa gagctagtgt aactactgaa gactatatca attttcaaaa
    26521 agtagaccaa gatactgcta aagcttttga agtcgcaaca ggtcaaaaag ctaaagaaat
    26581 aaatgattta ggcattaata gatctataaa tgaaaatctt gagtatggag aatatggagc
    26641 aaatttaggg tcattaggaa aaactttatc agaaaatggt ttaaagacat ctgtaattgg
    26701 aaatgctgat ataattgaaa ataatcaatt agttaaaaat agaaacttat gtttagtagc
    26761 tatggaccaa tatggaagga ttgattcagg taatattgat aatattaata agaaagattc
    26821 taaaatgcca tttggaatat ctacagacta cgataaatta ctagatgaaa ctaaaaaatc
    26881 ctataaaaat agtgatgcta tatttgtaga acttggagat acatatagat tagatatgta
    26941 tagattaaat ctaaatgata atacttatgg tacaatgaag aaaaatattg taaaaaatat
    27001 aaataaatat cttgaacaag tattttctat ggttggagaa aatgacactg tttatatagc
    27061 aagtgcattt ccaagtgacc tagattataa gaataagaga agactttctc caataataaa
    27121 atttagtgga gaagggaaag gtctactgga atctgccaca acaagaaagg ctggaattgt
    27181 tgccaattta gatgttggag tagatatact aggtacattt ggtcttgaaa ataaagagat
    27241 ggtaggtaga agttatactt tagtaaataa agaggacaat gttggctatc taaaatcact
    27301 ttatgaaagg atagtgtcta tatcttcaat aaggtcaact attataaatg gctttgtagg
    27361 cgtaatatct gcttcttggg taattgccat gtttgcgatt ttctttagaa attatatgcc
    27421 acataaagag cgtgtattca aagtacttaa ggagtttata aaattaggca taataatgcc
    27481 actatcattt atgttagctc ctttgatgaa ttttaaaact ccaatttcaa tatctttggg
    27541 aatatttgcg actacgctaa tattatactt gttaggtaga aaattattta aggacaatga
    27601 tataaagcac atgggatttt ttgcaacact tactatttta gtcatagtta tagattctgt
    27661 atttggaaca tacttaatgc aaaataacat aatgagttat gatgctgtca taggagctag
    27721 gtactatggt gtaggaaatg aatatgaagg tgtaactata gcaagtgcag tatttggctt
    27781 agcagtatta ttacattata agaaggtatc taaattactt gttgtaattt tttcgttaat
    27841 aatacttata actagtgcat atccttcaat gggtgcaaat gttggtggag ctatatcaga
    27901 atgtgtagca tatttgttgt ttataatgct tatatatgac attaaaatag attttaagaa
    27961 agctgtatta ttagctgttt cagctgtagt tgtcgttttt gcatttgcag ctttagatat
    28021 actttcaggt agtgaatctc atttaggtat gtttgtacag agaattttcc taaatggacc
    28081 aggagagata ttacaaacat ttggaagaaa aattcaaatg aatatgcaac tagcacagac
    28141 aagtgtatgg gtaaatattt tacttgtagg aattggagta attgcagtac ttatatttaa
    28201 accatctaga cactttagaa agataatgaa taattttcca atcttgttta aagggtttat
    28261 tgcatctatg gttggttgta taattactct tttagttaat gattctggaa tagttgctgc
    28321 atctacagca tctatatata tacttatacc actaataata ataaatataa atatgataat
    28381 atttgaaaaa aacaactaaa aaatttttta ctgttcatat aggatttaaa taaaaaatgc
    28441 aatatgatta ttaatgtaaa ctggatgctt acataaaaaa tcatattgca atttttatga
    28501 ttgattatgc aaaattctat gaagcaggaa gcctgtgacc ttagttatga gaggttcaga
    28561 atatgtattt aatctataga atataaatag ataaaggagg aactatgtta gatggaagaa
    28621 taatgggtct tgatgttggt gataaaacta ttggagttgc tgtgagtgat ttgatgggat
    28681 taactgcaca aggtgtaaaa acaataaaaa gagttggcaa gaaaaaagat attgaagagt
    28741 taaaagcaat aataaaagaa aaacaagtaa ataaaattgt atcaggatta ccaaaaaata
    28801 tgaatggaac tttaggtcca caaggagaaa aagtaatcaa gttttgtgaa ttggtaaaag
    28861 cagaaacagg tattgatgta gagttttggg atgagaggct ttctacagta gcggcagaga
    28921 ggtctttatt agaagcagat gttagtagac aaaaaagaaa aaaggttata gatatgttgg
    28981 cagcagtaat aattttgcaa ggatatttag attttaaaat aaattcataa aagaactata
    29041 aaattgaata cttatgatat ataatataaa taataaaaat aaaaataaat ttgaggtgaa
    29101 tgacattatg gaagaaaata taataaattt aatagacgaa aatggcgttg aaagccaatt
    29161 tgaaataata ttaacattag aagcagaagg aaaagagtat gcaatattaa tgcctttaga
    29221 tgatgaagaa gctgaagaag ctttaatctt tagaattgat gaggatgaag aaggtgaaat
    29281 attaatacct ttggaaagtg atgaagagta tgaaactgtt gtagctgtgt atactgctat
    29341 aatggaagaa gaaggtttaa attacgacga agatgaatca aatggactta actagataag
    29401 taattaagtt tgtatataaa aatcagatat ttattatatt tgctttaatt aaaccttatt
    29461 aattgtaaaa gcatttatag tatatatctg tttttttgtt ttttattaaa aataccaaaa
    29521 aatttatgaa ttttggtgaa taatatatct tttatgggta tatatttata ttatgagaat
    29581 aaattaaatt tatttaaatg tcttgacaaa aaatgaatta tcaattacaa tattatttaa
    29641 taaagattat caattgaaaa tagtaagggt gatgttatgg caaatacaat ggatttatta
    29701 aaagacaagt taaaagaaac tggttttaag attacgccac aaagaagagc aatagttgaa
    29761 atattgctta aacatgacca ttcacatcta agtagtgagg aaatctatga tttagttagg
    29821 gttgactgtc ctgaaatagg cttagctact gtatatagaa caatgcagct attggatgaa
    29881 ataggattaa tatcaaaact aaacttagac gatggatgta taagatatga gattagtcta
    29941 cataaagaag actgtcataa tcatcatcat cttatttgta aaaattgtgg aaagataatg
    30001 gaagctaaag aagacctttt agacaatata gaaaaagaga tacaatcatt gtacaaattt
    30061 aaaatacttg atcatgatgt taaattttat ggattatgtg acgagtgtaa tggagtaagc
    30121 gattcagaag aataaacttc tattgcttaa tgtcgatgga agaatagtat agaactttta
    30181 tattctatgc tattcttcca ttttttatta taaaccatct acaaaatgca aatatacagt
    30241 tttcaagatg cttatagttt taatattgaa aatataatta atcctataag tacaaaaatg
    30301 aatgattttt ctatgaaatt actaaatggt cctccaacag ttaaaaaacc taaagaaatt
    30361 ttcttttcgc ttagcggata aaaaattggt attccttgct ttgtaaataa atctcctaaa
    30421 aacatatgac ttgcataacc aatcgtacca taaaaagata aattattaat attagtgatt
    30481 aattctatct gttttagtaa aaaatatact attatagttg caaatatgct atgagaaaaa
    30541 cttctgtgct ttaaccaggg aaaaattgac aacattagac aaaaaattgt aaaatatatt
    30601 tcaacttcta tgatgtataa gcatatagct aatagtataa atattaatga tagaaaaact
    30661 tttcttagaa atgtgtgggt tagttttgct tcaataatta taattgcaac aaatgtaatt
    30721 attgcgctta aataaaaatt atcatttata tttattgaaa taaagaaaat aataatatta
    30781 acagcatata taaaaattct atatatgtat ttggatacat tgttttttag aatgaaattt
    30841 gagaccatag aattagattt atccaaatcg ggtagtacag caaaagtagc tgaaactaaa
    30901 atatcaacta aagatatagg aattttaaat attaaagatg tttggatagc tgttaagatt
    30961 cctattgcac aatgagtttt accacgcata aatcctccta aattatccga tattaaatca
    31021 tataatattt agaggatatc aaaataaaat aggtttgtca aaataatacg ttaaatgtat
    31081 tttaaatata gcttaaaata tgatacgaat tatggtacaa taagaataac tggtagcgag
    31141 tgcgtgattt gatattattt atgattgtag aacgtgttaa aaaattaaat agacagaagg
    31201 agatgatgca attgttcaaa aagaacacca acaagataaa ggtaatggcc ttgggtggac
    31261 ttaacgaagt tggaaaaaat atgactgttg ttgagtataa agatgaaata attgttatag
    31321 atgctggact tagttttcca gaggatgaaa tgttaggagt agatatagtt ataccagata
    31381 taacttattt agtaaaaaat agggataaaa taaagggtat atttattaca catggacatg
    31441 aagaccatat aggagctctt ccatatatat taaagaaaat aaatgtacct gtatatgggg
    31501 caagacttag tataggtctt atacaagtaa aacttaaaga acataaaatg aataatgtta
    31561 agttaaatgt tataggtcct agacaagtta taaagcttga taatatggaa gtagagtttt
    31621 tgaaaaataa ccatagtata ccagatgctt actctattgc aatacacaca gaccaaggta
    31681 taatatacca cacaggagat tttaagattg acttgactcc tattgatgga gatgttatgg
    31741 atatgcatag aatctgtgag ttgagcaaaa aaggagttct tttaatgctg gcagatagta
    31801 ctaatgcaga aaaaccagga tttactatgt ctgaaaagac tgttggggta ggtcttgacg
    31861 aattatttgc aaaaggaaat ggcagaagaa ttatagttgc tacctttgca tccaacatac
    31921 acagattaca acaaataata aatactgctg aaaagtttaa tagaaaagtt gctatatcag
    31981 gtcgctcaat ggtcaatgta gtcggagttg caaaagaatt aggataccta gatatttctg
    32041 atgacatgct tatagattta aatgatatat gtaagtatga agatagtgaa ttagtgataa
    32101 taacaactgg ttcacaaggt gaacctatgt cagctcttgc tagaatggct ttttcagagc
    32161 acaaaaaagt agaaataaag agtggcgatt tagttataat atctgctcat ccaataccag
    32221 gaaatgaaaa attaatatca agagtaatca atttcttatt tgaaaaagga gcagaagtag
    32281 tatacagtga tatagctgat atacacgttt ctggacatgc ctgtcaagaa gaattaaaac
    32341 ttatacatgc attagttaga ccaaagtttt ttatgccagc tcatggtgaa tatagaatgt
    32401 taaaaagaca tgctgaaata gctgaacagc ttggtatgga taaagaaaat atttttgtca
    32461 tgcaaacagg agatgtttta gaattagata aaaactctgc taaggtagca aaccgtatac
    32521 aaacaggaaa catattagtt gatggtctag gagtaggcga tgtaggtaat atagttttaa
    32581 gggatagaaa gcatttatca gaagatggtc ttatgatagt tgtagttact atttccaagg
    32641 atgagggtaa ggtcttagca ggtccagata taatttccag aggattcgta tatgtaagag
    32701 agtcagaaga tttaatggat ggagcaaagg atataattaa gaatgttcta aatgaatgtg
    32761 aagagaaaaa tattaaagaa tgggcttatt taaagaataa tattaaagaa aacctaaaag
    32821 aatatttata tcaaaaaact aaacgaaatc caatgatact tcctatcata atggaagtat
    32881 aatataaaaa aactataaat ttgaaaatta gacctcttgt aatttttaaa gtaatatcaa
    32941 aaatccaatt gatattatct taagaattac aagaggtctt tttaatactc atttaaaaaa
    33001 aatatatatt acataaaata ccaattataa caatctttta ttagtaaaaa ctacttatat
    33061 ataaatttta ctgataggag gattcttatg gatgatgttt caagacaaaa tgctataaaa
    33121 gctttaaaac aaacaaaaat ggaaatagca ggagagtatg gaatgaatta tgaagatgct
    33181 tttgaaataa tagaaaatgc gtctaataaa ggtgttttag aaggttactt taaaaagctt
    33241 gaaaagaaaa aaaatttagg tcaaggtata tctaggcatt tagaataaaa aaagttaaat
    33301 gtgagaaaat aagtttaaat aaactttaag aggtgacatc gatgaaaaaa ttagctagta
    33361 ctgctttggc tatattaatt gcgcttactc ctttaagctt ttcttttgca aataataagg
    33421 aaaatgctga tgccaaccaa ctaaatatat cttcaaaatc agcaattttg atggatgttg
    33481 gtagtggaca aattttatat gaaaaggatg ctcataaaaa gcttcctcct gctagtgtaa
    33541 ctaaggtaat gactatgcta cttatagtag aagctttgga ttcaggcaag attaagcttg
    33601 atgatgaagt tcaagtaagt gaaactgcat ctagtatggg tggtagtcaa atattcctag
    33661 agccaggaga aactcaaaag gttgatacat tattaaaagg tatagctgtt gcttctgcaa
    33721 atgatgcttg tgttgctatg gctgaacact tagctggaag tgttgaagga tttgttgata
    33781 gaatgaatgc taaagcaaaa gagttaaata tgaatgatac tcattttgca aatacaaatg
    33841 gacttccagt tgcaaaccac tatacatctg ctcatgatat agctttaatg tctagagaac
    33901 tattaaaaca cgaaatgata agtaaatact taactacatg gatggataag gttgtagtag
    33961 ggaagaaaca agttacagta ggtcttgcaa atactaataa acttataaag cattatcaag
    34021 gagcaactgg tgttaaaact ggttttactc aagaagcaaa atactgttta tcagcatctg
    34081 caaagagagg taatactcat ctagttgctg caactttagg agcagagact tctccagaaa
    34141 gatttaatga tgcctctagc cttttaaact atggatttgc taattatgaa agtgttaagt
    34201 tatgtagtaa aggtgataat atagcaacac ttacattgga taaggctgat gaaaacaaag
    34261 ttaaattggt tgctaaagaa gatttaaatg ctcttattaa aaaaggaagc tctaaagaat
    34321 ttgagaagaa aattgaaata gtaaaaaatc ctaagatgcc aattaaaaag ggaactgttt
    34381 taggaaaaat aaagatatgt aaagataaaa aagtaatagg cgaagtggaa ttgataaata
    34441 ctaaggatat aaataaggca agctatctac aaatgcttca aagaataatt gataatatga
    34501 tataaataat tatcagatga aatataatta taatacacaa agatatgatt ataatacaca
    34561 taaaaaatac ccttatgtag ttatttgcca taggggtatt tttatttacc atatagaagt
    34621 attttataat cttatgattt ttatagaaat atagaaaagt ttatgtatct taaaatatca
    34681 tttgatttaa tatcatatat agggttgttt aacaattatc taagtaaagg catactacca
    34741 gtaagtttat tcactttctt tttattccca taaattgcta tcccaaaata ctgtaactca
    34801 tcttctggaa cactagcaat cttttgtgta aattcttcat aaagattgca actttgtgct
    34861 acatctgaaa aatctacaac agttaaatcg ttaaattcca aagtatataa ttttttacgt
    34921 aaatctttta ttatttcttt gtttcctttt aaaataggta caggaatgtc aataattcct
    34981 aagtggctat tacctgtttt gtcaattaca tctggcccaa cagtttctgg ggcatgtttt
    35041 cctagtgtaa ttcccattat agctgctgta ttggatataa ttcccattgg caaattttcg
    35101 tctattacca tgacacattt tgaattttta gtttccattt ttatttctcc tttttacctt
    35161 atttaaagtt gtttgaatca tcatttataa atatattttg atactgcttt ggtgtaagac
    35221 caataaaatt cttaaaaaag tttgtaaagt gactttggtc tacaaatcct gtttgtatcg
    35281 cagcatctat aggttctacg cctttttcta aaagcttttt agctttgttt acccgtatat
    35341 tttctaggta tctatatggt gtaatacctt ttaatttcgt aaaattacga agtagagagt
    35401 acttattcat acctgctata gtgcttaatt cgtcaagtac tatatgttca gcataattat
    35461 tttctagata atcacatact gcttgaattt ctatatttgt attttccaag ttagattgca
    35521 aatttggctc tgtatgttct tcaattaatt gttcaattag gaagaaaaaa agctcttcct
    35581 ttttaaaatc caattcttct tccatgatta tatagtgtaa ttcttgtagt agaggtacta
    35641 gctcactgcg aaatataaca ggttgattaa attttggtaa ataattttta cctgtaattt
    35701 caaagacggt ttttttcatt atttctggct taatattgat acatctgtaa tcaagtactt
    35761 tatcatctat ttgttcacaa gtatgactgt caaaagggtt aaaaagtagc aaatctccag
    35821 tacttgtggt atactcttta tttttacaag ataaatatct ttgacctttt tctataaaac
    35881 caattacata atgttcatga aaatggtttg ggaatttttg cattatgcct ttaaatctat
    35941 atgcttcaat ttttaattcc ctatcaaagc atactgtgcg ttcttcttgt ctcacttagg
    36001 taacctcctt tcatgttata caaagtgtaa cacatatttt tttatacttc ttgtataata
    36061 ttgactaaga gacaataatg tcaattcatg tcaatataat attacactta cagtaggtgt
    36121 aattattata ttttcacaat gaatatgata taataataaa agttataaaa taaaaagcaa
    36181 attttaattt tatgcctaga agttaaaatt attataatgt aaaataattt tgattataag
    36241 ctatttaatt gttataataa tattaaaaat ttaatttagg agatgtacat taatgttaag
    36301 tatgaatata ggagaaatag tagcaagttt agttggtata gctatggcaa tatcaataca
    36361 tgagtttggc catgcttatt cagctcactt attgggagat gatacagcta aagcttatgg
    36421 tagaatgaca ttaaatcctg taagacatgt tgacccaata ggtcttttgg ctatgtttat
    36481 ccttaagata gggtgggcaa agccagtacc agtaaatcca aataatttta aaaactataa
    36541 gataggaaac ctgatagttt cacttgcagg cgttttttgt aatgttttga ctgctatact
    36601 gtgtgtaatt atcaataagt atgtgcatat gtatgctata aatacaatag ctggatatgt
    36661 gcttatatat agtatgggat ttgcagcttt taacttactt ccgatacctc cacttgatgg
    36721 atggggagtt atatctacat ttgtaccata taaatggaat gaatatttgt ataaatttga
    36781 aagtatgagt tatataattt tattaattgc tttatttact ggtatatatc aaataatact
    36841 atcaccaata tatacagtgt tgctaaaaat agtatattta tttgtttaat ataataaaca
    36901 gattaaagag ggattgatat gaagtataat atacaattac aagtctatga gggaccatta
    36961 gatttacttt atgatttaat aacaaagcat aaaatagata taaaggatat atctataata
    37021 gatataacta agcagtatct aaattatttg aaaatgctag ataaaatgga tttagagata
    37081 actagtgaat ttataactat ggcatcaaaa cttttagaga taaagtctaa atatctgctt
    37141 tataagcaaa aagatgaaga agaagaccca agaatagaac ttatggaaaa gttagaagaa
    37201 tatagaaagt ttaaggtagc atcacaagat ataaaagaaa atataactta tgttaatgag
    37261 agattttata gaaataaaga agagataatt attgatgaca atgtggattt agaagatata
    37321 tcaattgaag caataaaaaa tatacttcca tacatattta aagttaaaac atcacagata
    37381 gaaaatgcta atgatgagaa actagacaaa atagtaagga agaagataat atctgtggaa
    37441 gaaaagatat tgtatataag agatattata aaagataaga ttgaagttac ttttacaaat
    37501 attataaaat catatgaaaa tgatgaaata atagctactt ttttatctat attagagctt
    37561 ataaaagaaa aagaaatagt agtagtacaa gacatatttt ttgatgatat tctaataaga
    37621 aaaagttcgg agtgttaaaa tgaaaagaga agatataaag tatattatag aatctgttat
    37681 gtttgcatat ggggaaccaa taagtataaa agaattaaac tatataataa ataaagaact
    37741 ttcatcaaaa gaaatagaga ttatgttaaa tttacttatt gaggagtaca gagaacaaaa
    37801 tagaggtatt caaataatca agctagagaa taagtaccaa atgtgtacaa ataaagacta
    37861 tgcagaatat ataaagaaga ttattgaacc aaagaaaaag aaaagtttga gccaagctac
    37921 attagaaact cttactataa ttgcctacaa acaaccaata acaaaggtag aaatagagga
    37981 tataagagga gtaaaatgtg ataaggtatt acaaactttg tttgaaaatg aacttataag
    38041 agaagctggt agattgaata agatagggaa accaataatt tataaaacaa cagatgaatt
    38101 tttaaagttg ttgaatatag aaagtcttga agaattgccg cctatagaaa attatcaaga
    38161 agtggcaaca aatgaataaa aatataaaat cacaataatt tagtatgtaa ttttaaattt
    38221 taaaagattt aaaatgctct aagttgttgt gtttttttgt ataaatataa aattataatt
    38281 ctcttaaaat aaatatggat aattaagtat aaatagtaat tttttgatga taatataaac
    38341 atggagctta atgaattatt taattttaag tatttaataa tagctgtaat ttttattata
    38401 agtgtaacta tgttgatttt aatatctcat ataaacatct taataatagc tgatataaac
    38461 aacaaagata tttgtttaaa gcttaatata aaatacatgt ttaatttaat aaatataaat
    38521 agacaacttt atccagctga aaatagtaaa aataatgata aaaaagaggg gatgaagaat
    38581 aatatagatt caagtatatt attagctgat gaccttttga gcatttatag attattaaaa
    38641 aagataaaaa tacatgaact ttattcaaat attaattttg gaactggaaa tattggctta
    38701 acatcttctg tatatgtatt gataaatact ttgtatggaa atttatttaa tatgattgat
    38761 gcagaaaaaa tgtatttaaa tgtaaatcca gattttacaa aagattatgt tttaggaaat
    38821 ataaggatac atataaggcc aagaataaaa gctttattta atattataat aatgattaat
    38881 aaaattatga ataaaaataa aggaaataag gaaggtgata gtaatgagag caacaggttc
    38941 gatacagagt cttatggaaa caactcttga aacaattaaa ggttctatag atgcaaatac
    39001 tattatagga gaccctataa aaacagatac tacagtggtt gtacctatat caaaggttac
    39061 aattggcttt ggtataggag gaggagaata ctcaaaagga tatgatgata aagataggga
    39121 aattgaatta aaaaatgaaa aatcagatac gaattttgct ggaggtagcg caggggctat
    39181 atctgtacaa ccagtagcat ttgtagtagt tgaaagtgga gagactagaa taatgagttt
    39241 agacagtaat atcaatctag tggataatat attatctata actcctagag tattggagaa
    39301 aattcaaaat atatcacaaa gtaataagaa tcaagataaa aacaatatgt aagaataaaa
    39361 tatttttaaa tatgtatata gttttaagta aagtagtggg gttagtataa atcccactat
    39421 tttgttgtgt actttaaaca tttatatcta ataagatttt agtttaaaac aatttaaata
    39481 gataataaag ttgatatata gtataattat aaaaagaaaa gaagtattat attatagata
    39541 tataaacgca tttgagatat aagagggagt tataaatcat tagttttgag gtgaatgtta
    39601 tgagcgataa agaattatct attttgttgt tagaaagtat gaataatttt cataatttaa
    39661 taaagattat taataacgaa agatataaaa aagataaggt tcttacagaa agacagttct
    39721 ttgccttagt aaaaataaga aaacatgata aaatagagct taaaaatcta agtagagatt
    39781 tacatgtatc tacttctagt ctgtgtatac tacttaataa attggttgag caagagtatg
    39841 tatataggga agaagatagt agagatagac gaaatacttt ttatggaata actaaaaatg
    39901 gagaaaagat attggataat gaaatactaa agtttgtatc tataataagt gataaaatgg
    39961 attgcttaga tatagataat aaagataaat tatttacttc tttggaagag tctaaaaata
    40021 taatagaaca attattttaa aaaggagaat ttattatgaa tataaagtat tctaaagaga
    40081 tattaaaaag tttagaaaat gctataacag tagtagctct atttgaggga gaagatgttt
    40141 ctacgacatt tgataaaata aatatgataa gcagaaattt taattctaaa gaaaatagta
    40201 tagatactgt aacattggtt gaaaataaca acttggtaaa tgtttgtctt gttggttttg
    40261 gtaagagaga gttattgaat agagaaaaaa ttagaatcat aggtggtaat ttgtgtaaaa
    40321 aattaaaaaa tatattgaaa aatgaagcat ataagagtag tgatgttaat gtacttaatc
    40381 ttaatttaaa tagtgatgaa ataggttctt ttgtagaagg gatattactt ggaaattata
    40441 agtttgataa gtataagaca aaaagtaagg attttgaaag aaaagaagtt gatactataa
    40501 ctatatttac tgaaaaagaa gttgagtgtc aaatagaaaa ggctaaaata ttagctaatt
    40561 caactataat agctagaaat ctagttaatg aaccatcaaa cgtaatatat ccaaaaacat
    40621 tagcaataga aacagttaaa cttggtgcag agttcgggtt taatgttgat gtttatgaag
    40681 aagaaaaaat aaaggcattg ggaatggatg cttttttcgc cgtttcaaga ggttcaatca
    40741 ataaaccaag attcatagta atgagatact ttggagataa agaaagtaca gatatattag
    40801 gtctagtagg taaaggattg acttatgata ctggtggata ttctttaaaa tcaaatgctt
    40861 ctatgctaga tatgaagaca gatatggctg gtgctgcgag tgttataggt gctatgtgtg
    40921 ctatatctca aagtaaatta aagaaaaatg ttatagcagt agtggctgca tgtgagaatg
    40981 ctttatcagg aggttcatac aaacctggag atataattag ttctatggca aagaaaacta
    41041 ttgaagtttt aaatacggat gccgaaggta gacttacatt agctgatgca atatactaca
    41101 ttataaacaa tgaaaaagta acaaaggtag ttgatgtagc tacattaact ggtgctgctt
    41161 taacattgtt aggaaatgtt gcaactccta tagtaacaaa taatgatgac ttttattgtg
    41221 aattagaaaa agctaccact ttatcaggag aaagggtatg gaagatgcca atttatgatg
    41281 aatttaaaga tatgataaaa ggagaagaag cagaccttaa aaacactggt ggtaaaaatg
    41341 ctggatgtat aacagcagga gcttttattg gtgaatttgt tgggaatact ccttggatac
    41401 atatggatat agcggggaca agtacatcat caaaatcaat tggatacaaa gcaaaggggg
    41461 ctacaggaga acctgttaga acattatact atttggcaga aatctaaaaa acaattataa
    41521 aatataattt ataaagccac atggatattt ttgtaattta agattatcta tgtggcttta
    41581 ttttttattt aagtaaatta tttactcttt ttctttttct caagtataaa agtatctcta
    41641 ttaaataaaa gagcaggtat gtacataata ctagtaacaa aaataaacgt aaaaatagca
    41701 gttgtgctat gacttaaaaa accataatag tattgtgagt tggtaaatgt gtttagtaaa
    41761 aatatgaatg aaaaataaat aaaacatata gctaagttat ctctaagtgc atatctgtta
    41821 actctaaatt ttctaacatc aaccatatat atatctgcat aaattatcaa gcacttagag
    41881 aagataaata taaaatatat taagctagga aattcatagc ccaagttttt agaaaaaatg
    41941 agttctccaa ctgaacaaac taaactccaa gaaaaaaata tattaaaaag atgatactgc
    42001 ttaaaaatta gtatggctat acacagatat atacagatat aattgattcc aattggtaaa
    42061 gagtttagag tactataatt acctgaagaa ataagtaata attgctctag agccataatt
    42121 attacaagta atgtacaaat tatcttctca actgtatagc tataaggtaa aatatttttg
    42181 gttagttttg gacaatagta taaaaataat ccaaatataa agagacttac aaattgttca
    42241 ctagaaaaaa gaaaaatttt aaacatataa cattctctcc tataataaat ttaatatgta
    42301 tctatataaa tatattcatt atatctcaat ttaatatata aaaaagataa taatagttag
    42361 actttttata tgaattttaa taggtaaaat atcctattgt tttgtagata tatcctaatt
    42421 atgtcaaaaa ataaaaaaat ttttatttat tagagttttt ggaaataata ataacagata
    42481 ttataattaa ttaacagttt ttgtaagtat ttgacaatag agagggtgta acaaatggga
    42541 ataatagagt cagcatcaaa attggctgag atggttcatt tattggctgt tgaaaagggg
    42601 ataactgata tagaagcatg ggatgaagct gtgaaagaat acagcaaaat ttatgaagaa
    42661 agaagaaatg aatagaatga taaaaaatga aaacttgatg ataaaaaata actttattta
    42721 aagaaattca atttttatag aaatattaaa aataatataa ataaaaagat ggtatttcaa
    42781 atgtaagtaa aaaatcattt tgggatacca tccttattat ttattttaat aatatataag
    42841 taataaatct tacttatcca tattttttat gtaacctctt ttttctagct tttttatatg
    42901 ctccttacgt atttcatcaa gattaatacc atattgttct tctagcttaa acatcatagt
    42961 aacacatgtc tgagctacat ccattagttc cttagcagtt ttctttataa tatcaacttc
    43021 atctaaatca ttattttctc cacttagatt tctgaattta cctatacatt cagctaattc
    43081 accttgttct tcacccattt tgataaatgt agattctagt gttgggtcta aattattaag
    43141 ctctggtaaa gatatagttt ttagtttcat aaaagctcct ttcaagttat tcgtatttat
    43201 actaaaacat cataacaaaa ataatactaa aaaaaaactt taaattcaac ataaaaactt
    43261 acatatataa taaaaatcgt gaaataaatc tatatttgtc ttaatacagc ctcatataaa
    43321 acttctccaa taggtttatt tattacaaga gaagctgact tatcatagac tgtatttgct
    43381 ttattaataa gagcaatata atcacctttg taataatcta taaaacttgc tgctgggtac
    43441 acagctaatg atgtacctcc tataatcaat aaatcagcat tacttatagc agaaattgtt
    43501 ttagtaatga catcactgtc aagagcttcc tcataaagta ctacatctgg ttttactata
    43561 gaaccacagt tgtcacaata aggaatatta cctcccagat ttaacataga ttctaagtca
    43621 aaaaacttac cacatttagt acaataattt ctatgtacag aaccatgaag ttctagcaca
    43681 tttttacttc cagccatttg atgaagtcca tcaatatttt gagttatgac agctttaagc
    43741 ttacccattt cctcgagttt tgctaaagct atatgagcat tgttgggttt tgcattagga
    43801 tatattaatt tatccttata aaattcaaaa aattcttctg gatatctaac aaaaaaagta
    43861 tgtgaaacta attgttcagc agtaaattgt ttattgagtt tttggctaaa taatccagta
    43921 gaacttctaa agtctggaat attagattca gttgaaacac ctgctccacc aaaaaataca
    43981 atattattgt gattagctat taagtctttt aagctatttg catccatagt tacacctcca
    44041 aattattata tataaattgt actacatatt aggtctttta tgttttatta atttaaataa
    44101 atatgtagtt taataagtta aataaaggga atataaataa aatgtataca gagtataaat
    44161 agacaatatt tactaaaata acaagttgtc gtataattat attaaaattg ttttagtgta
    44221 taagaagggc gggggaagta cgtgaagaaa aaagcagctt tagcaacatt ggctatgtta
    44281 cccttaggtg tggtaaatgc acatgctgat ggagatatag gtatagtgac tataaattat
    44341 ttaaatgtaa gaaatgaacc aactgccgaa agtaacatag cctttgttgc taaaaaagat
    44401 gataaagttt tgattaaaga ctcttctaat ggatggtata aaataaaagc tgaatctgga
    44461 caagaaggtt gggcttcatc aaaatatata gcaaaatcaa atagtgactc tttaagaacg
    44521 tctacaaata aagaaaaaca agttatttca aatagtttaa atatgagaaa tggagcaggt
    44581 acaagttaca gagtaataac tgtactaaaa aaaggtcaaa aagtagaagt aatatcagag
    44641 agtaatggat ggtctaaaat caaatatgat ggaagactag gatatgtatc tagctcttat
    44701 ttaggagacg tttcaaactc aactaataaa tcaaaaacta aacaagtgaa tacaacttca
    44761 ctaaatgtaa ggagtggacc aaatacaagt tatggtttgt taggcaagtt gccaaaagga
    44821 agtaaagtag aagtaatatc agaaagtaat ggatggtcca aaataaagta taatggaaaa
    44881 gatgcctatg tatctagtat gtacttatcg gatgtaagtc aaagtaattc agacaattct
    44941 agtcaaagca atgataaaaa gaatactgat aaggttgtaa atacagcttc tttaaatgta
    45001 agaagtggac caggttctac atatagtaag ttgggaaaag tttataaagg aagtaaagta
    45061 actgtactat cagaaagtag tggatgggct aagattaatt ttaacaataa agaagcattt
    45121 gtagtaggca attatttatc tacttcagca gatacttcaa ataataactc aaatagtaac
    45181 tctgataaca gttctaatag taatggcaat aattcttcat catcaggtca agtaaatggt
    45241 atgtcaggta taagtggggc taaaattgat tataaatctt tgagttatac tttagaatct
    45301 catataagta aacaagttga gaaagcagca tcaggaggaa atgtgatagc tccaagtaat
    45361 aggaaaagca ctccaagtcc tgaatttagt actttttcag ctcaaagaac aagctcattt
    45421 gtaaatgcaa gttcaagtga tatagaatat tatttaaatc ctaaaaattt tacaaatact
    45481 actaaaggta tgatgcagtt tttaaagatt aacagttata gagatggtat ttcagaatca
    45541 agtcttaact cgtatcttaa tggtttatct tctagtgtat ttaaaaacca gggagcagcc
    45601 tttataaatg ctgccaagaa gtataatata gatgttgtat atctagtatc tcatgctatg
    45661 tgggaaactg cttatggtaa gtctacactt gcccaaggtc aaacattaac atcttataag
    45721 ggacaacctc ttagtaagcc agttaaagta tacaattttt ttggtatagg agcaatagat
    45781 aaaagtgcta atgtttcagg tgcagaagca gcgtattcca atggctggac tagtgtagaa
    45841 gctacaatag atggctctgc aaagtggata tcacaaaatt acgtaaatag ttctaagtac
    45901 aatcagaata ctatctacaa gatgaagtgg aattatgatt atacatggca tcagtatgca
    45961 actgatgtaa actgggctaa tggaatttct ggaattatgg aaaatttaat tggtctttat
    46021 ggaggaggaa gtagtttggt ttttgaagtt cctcaatata agtaatacat aaataaaaaa
    46081 tatagactat gggtagtttt cattttattt aaattatcta tagtcttttt gtatataatt
    46141 tataatctgt aaatttaatg ttaacaaaac ttttatgtta taatattaat tctaagtaaa
    46201 tataagtgag taataggtag aaatagataa aaagtggtaa taatatatat aaagataatt
    46261 ttgagaaagg aggatatata tggaaagtat taaggaatat ttggataagt tagaaattaa
    46321 taatagtggt cttggaaagc aacttaaaga agtttatata aatagagtag tttattttaa
    46381 ggaagataag atagtttatt tttatctaac ttctaaagat attgtttctc atgaactttt
    46441 agataaattt aaagaagaat tgatgtataa actcgattat tttaaagata tgaggatgaa
    46501 gataagattt actggtcttg aaagaaaatc caataaagat gttataaaaa aatattggaa
    46561 taatatattg tatatattaa agtatctttg tccatctatt gcagggtggt ataaacaagt
    46621 agaatttctt tgtttagaag aagaattaaa aataaaactt ccaaaaggta tattttatga
    46681 gcgattaatg aaaaaaaatg taacttatgt acttaaaacc gtgcttagcg aagagttggg
    46741 attagattta aatataacaa tagaaaaagc tgttgatgaa aaggtaaata aagaaagact
    46801 cataagaatc aatgatagag aaatggaaga aaaaattagg gctttagaaa ttggaaaagt
    46861 taataactgt gaagaaaatg aagaggaaag ctatgtcatt aagtctgatg tagatgaaaa
    46921 tttaatctat ggagataatg caaatgctat gattgaaaat atagttgaat taaatgcatc
    46981 ttctggaaca gttgcagttg ttggagatat atttgatgtt gacactaaag aacttaaaaa
    47041 cggaaaaata cttatgatag cttcaattac agattatact agctcaataa gctgtaaact
    47101 ttttttaaca gatacaaata aggatggagt acttgaaaat gttaaaaagg gagcatactt
    47161 aaaaatcaag ggtgacatag tttatgatac atatcaaaga gaaattagta tgatgattag
    47221 tgggataaga aaagaaacta gaatagagag agaagataaa tcagaggaaa aaagggtaga
    47281 actccatgca catacacaaa tgtcttctat ggatgctatt tgttctgtta aaaagcttgt
    47341 agagcgtgca gccaaatggg gtcattctgc tattgctata acagaccatg gtgttgtaca
    47401 aggatttcca gatgctatga atgcaggtaa gtcaaataat ataaaaatac tttatggagt
    47461 agaagggtac ttggttgaag atgattctct cattatagag gatgcaaatg ataaagaact
    47521 ttcgcagaca tttgttgtat ttgacataga gacaactggt ttttctaata caaatgataa
    47581 aataactgag attggtgctg taaaaataga aaactttaag attgtagata gatttagtga
    47641 gctaataaat cctgaaaaag atatttccta taagatacag gaattgacag gaataactaa
    47701 tgaattaatt aaagacaagc caaccattga agaaattctt cctaagttta tggaatttgt
    47761 tggagatagt gtattagtag cacataatgc agagtttgat accggattta tatcgcaaaa
    47821 atgtagggaa caaggcttgt tatataataa caaaaaagta gatacactta tgttagcaag
    47881 agtaatgttg ccaaacttaa aaagacatag attaaatgtc gttgcaaaag aacttggtat
    47941 tcctctttta aatcaccata gagcagtgga tgatgctgag gctacagcac ttatatttaa
    48001 taagtttttg cagatgctta cagaaaaagg tgcaaaaact ctaagtgatg taaacaatat
    48061 acttggaaag attgattaca caaagcttag cacaaatcat ataaccttga tagcaaaaaa
    48121 ttctataggt ataaaaaatt tatataaaat aatttcagat gcacatgtaa atcatttttt
    48181 tagagcacca agaatcctta gaagtgtatt aaatgaatat aaagaaggat taataattgg
    48241 ttcggcttgt gaagctgggg tggtttttca agctgtaaag aaaaacatgt ctgatgagga
    48301 aatgaaaaaa ataatagatt tatacgatta tattgaagta atgcctatag ataataatag
    48361 atttatgatt gataaaggag aagtaaagga tgaagaagag ttaagggagt tgaataggaa
    48421 attaattgat acagccaaaa aatttgacaa aattccagta gctactgggg atgttcattt
    48481 tttagacaaa catgaagctg tcttaagaaa agttcttaaa tattctcaag gttttaaagt
    48541 agatgaagaa gaaacttatt tacattttag aacaacagat gaaatgttgg aagaatttag
    48601 ttatcttgga gaagaattgg catatgaagt tgtagttgaa aatagtaatc tgattgccga
    48661 tatggttgaa gatataaaac ctataccaga tgatacttat cctccaatta tagagggctc
    48721 agatgtggag ttaagagaaa tgtgttacaa aaaagccaaa cgaatctatg gagacccaat
    48781 accagaaata gttcaaaaaa gactggatag agaattaaat tcaataataa gcaatgggta
    48841 tgcagttatg tatattatag ctcaaaaact ggttgcaaaa tctctttcag atggatattt
    48901 agttggttca agaggctcag ttggctcatc ttttgcagct actatgagtg atataacaga
    48961 agttaatcct cttccagcac attatatttg tgaaaacgaa gactgtaaat attcattctt
    49021 ttatgaaata ggtgaatggg gctcaggtgt tgatttacca gacaaggatt gtccaaagtg
    49081 tggaagaaaa cttgctaaaa acggtcatga tattccattt gaggttttct taggttttga
    49141 aggtgataag gaaccagata tagacttaaa tttctcagga aattatcagc caacaattca
    49201 taaatacaca gaagaactat ttggagaggg gtatgtatat agggctggga ctataggtac
    49261 tgtagcagaa aaaacagctt ttggatacgc aagaaaatat gtggaagaaa ataatataag
    49321 tgtaccaaat gcagaagtac ttaggctttc aaatggatgt actggagtaa aaagaacctc
    49381 aggacaacat cctggtggag ttatggttat accagactat aaagatgtat acgattttac
    49441 acctatacag tatccagcaa atgatacttc ttgtggtgtt ataactactc actttgatta
    49501 tcattcaata agtggtagaa tacttaaact tgatatactt ggacacgacg gtcctaccat
    49561 tataaggatg cttgaagata tgactggaat aaatataaca gaaattcctt tagatgataa
    49621 agagactatg tctctattta catctacaga agcattaggt gttacaccag aagaaataaa
    49681 ctgtcctata ggttgccttg ctgtaccaga gtttggaact aagtttgtac gacaaatgtt
    49741 acttgacaca aaacctacta catttgcaga acttgtacgt atatctggtc tctctcatgg
    49801 gacagatgtt tgggtaaata atgcacaaga cttagttaga gaagatatag ttggattaaa
    49861 agatgttata tctacacgag atgacataat gaactattta atatttaaag gattacctcc
    49921 caaaatgagt tttacaataa tggagagtgt aagaaaaggt aaaggtctaa aaccagaaca
    49981 cattgaagaa atgaaaaaaa ataatgttcc agaatggtat ataggatcat gtaaaaagat
    50041 taagtacatg ttcccaaaag cacatgctgt tgcttatgtc atgacatcat ttagaattgc
    50101 atattgtaaa gttcactatc cagaagcatt ttatgcgact tattttacga caaaagttga
    50161 ggattttgat gcagatttaa ttgttaaagg attagatgct ataaaatcaa aaataaatga
    50221 aattgagtca ctgggaaatg atgcaaccac aaaagaaaaa ggtatgttga ccgttttaga
    50281 agttgctctt gaaatgtatg ctagaggaat aaaattatta ccagttgata tatataaatc
    50341 agatgcaact gagtttatag ttgtaggaga aaaaacatta cttccaccaa tggcagcaat
    50401 acaagggctt ggaggaaatg cggctataaa catccaaaat gaaagaaaaa atggtgaatt
    50461 tatatcaaaa gaagatttga gaaagagaac aaaaatatca aaaacggtaa tagaaactct
    50521 tactaatcat ggttcacttg agaatatgag tgagagaaat caattgtcat tgttttaagt
    50581 tagcccaaaa agttgcaaat aaaagaattt tatgatatca tagtatagaa aatagtatac
    50641 tttgcagaaa ctaagagtga gacagctgtt ctcactcttt tattttaaat atattattaa
    50701 aaagttggtt tatttttatt aaatatattt tatttaagat tatataaact aatcatttac
    50761 aattgaatag gaggaacttt aatgaaaaaa aatttagaag ctacaattga ggagattgta
    50821 actaaaataa cagatgaaca tggatttgaa atggttgatg ttgaatatgt aaaagaagca
    50881 ggagaatact acttaagagt atacatagat aaagaagaag gaatatcttt aaatgaatgt
    50941 gaattagtta gtagagaatt aagtccaata ctagatgaaa aagaccctat aaaagaaaat
    51001 tactttttag aggtatcttc tccaggactt gatagagcat taaaaaaaga cagagatttt
    51061 gttagatatc aaggtagaga tgtagattta aaattatata aaccattaaa tggatgtaag
    51121 caatttgaag gtgaacttgt aggattaaca gaagataata atataaaaat cattgcaaat
    51181 ggtaaggaaa tggaatttaa tagaaaagat gttgctattg tcagattagc aataaagttt
    51241 tagtggtata ttaaataggg aggatataaa aaatgaatca tgaatttatg gaagcattag
    51301 atgaattagt agttgacaga ggtatagata aagaaatact tatagatact atagaacaag
    51361 ctcttttaac tgcatacaag aaaaactttg gttcagcaca aaatgttaga gttgaatttg
    51421 atagagacaa gggagatata aaagtatttt ctcaaagagt tgttgttgat gaatcagatt
    51481 tatatgatac tttcttagaa atagagttag cggatgctag agagataaac cctaattatg
    51541 aattaggtga tattatagaa catgaagtta cacctaaaaa ctttggaaga attgcagctc
    51601 aaacagcaaa gcaagtagtt gttcaaagaa taagggaagc tgagagagaa atagtgtata
    51661 atgaatttat agaaaaagaa aatgaaatag ttacaggaga ggttgctaga gcaaataaaa
    51721 atgttgttta tgtaaatctt ggaagaatag aaggtataat gactcaaagt gaacaaatac
    51781 catttgagaa ttataaagca ggtcaaaaaa taaaattcta tatacttgaa gttaaaaaga
    51841 ctaacaaagg acctcaaata gttgtatcaa gaagtcatcc gggtctagta aagagattgt
    51901 ttgaagaaga agttcctgaa atatatgaag gaatagttca aataaaatct gtagcaagag
    51961 aagcagggtc aagaactaaa atggcagtaa aatctataga tgaaaaaata gacccaattg
    52021 gagcttgtgt tggaccaaaa ggacttagag taaaaaatat agtggatgaa cttggcgatg
    52081 agaaaataga tataataaaa tatagtgaag acccagcaga gtttatatca gcagcactta
    52141 gcccatcaaa agttgttaga gtagatatag atgaagatga aaagtctgcc ttagtaatcg
    52201 ttccagatta tcagttatcg cttgctatag gtaaagaagg tcaaaatgca agactagcag
    52261 caaaattgac taactggaaa atagatatta agagcgaatc tcaagcagaa caagaaatgt
    52321 taaatcttga aaattccaaa gaaatagaag ctgaggatgt tgaagctgaa tttatcgacc
    52381 aagaagagtt aggtacttca gaggataatt ttagtgaaga agagtaagga gggatgattt
    52441 tgaaaaaagt aaaaaaagtg cctcaaagaa aatgcatagc atgtcaagat agagactcta
    52501 aaaaagagct tataagaata gttaaaaata aagaaggaaa aatattttta gacccaacag
    52561 gaagagccaa tggaagagga gcatatgtat gtaaaagctc tgaatgtcta aaaaaagcta
    52621 taaagagtaa agcattaaat aaagctttta aaatagatgt tccagatgaa gtctatgata
    52681 atctacttat ggagttagaa gaatatgaaa aataataaag aaaaagtact ttcgttctta
    52741 gggctcgcaa ctcgtgcagg gaaaatagtg tctggtgatg attcaacttt gcttgacctt
    52801 aaaaaaggaa aagtaaattt gattttaatc gcagaagatg catcaaataa tactaaaaaa
    52861 ctttttaaag ataaatcaac ttttagaaat attccatatc tatttttttc aacaaaagag
    52921 gaaataggat ttgcaatagg aaaatctcca agagcagttg taggaataaa agatgaaaat
    52981 ttttctaaaa agataattga actaatagaa atttaaaata aaataggggg tgatcttgtg
    53041 tcaaaaacaa gagtatacca aatagcagaa gaattaaata tatcaaatga agagcttata
    53101 aataagttag ctgaattaga tataaatgta actgacaaag attcagtatt agaaggtgaa
    53161 gagttagaat tagcacttga aatgttaggt gaagatttat ctcaagaaaa tggaaatgtt
    53221 atagaaatag atggaaagtt gacagtacaa gtattagcaa cgaaattaga taaatctcca
    53281 tcagaaataa ttatgaagct tatgaaaatg ggaactatgg caacaataaa tcaagagata
    53341 agttttgaga ttgctgcttt ggctgccaaa gactatggat ttgaattaac agtagctgaa
    53401 agtgatgata cagaagcttt agaaatagaa gctttaatgg aaattgaaga agataaagaa
    53461 gaggatttaa aacctagacc accagttgtt acagttatgg gacatgttga ccatggtaag
    53521 acatctttac tagatgcaat aagaaaaact gatgtgattt caggtgaagc tggaggaata
    53581 actcagcata taggtgcttc agaagttaaa atcaatggac acaaaatagt atttttagat
    53641 actccaggac atgaggcttt cacatcaatg agagcaagag gagcacaagt tacagatata
    53701 gcaatattag tagttgcagc agatgatggt ataatgcctc aaacagttga agctataaac
    53761 catgctaaag cagcaggtgt acctttaata gttgctatta ataaaataga taaaccaggt
    53821 gcaaacccag ataaggttaa acaggaatta gcagaccaag gattattagt tgaagactgg
    53881 ggtggagaag taatagcagt tccagtatca gctaagaaaa aagaaggaat agatacactt
    53941 ttagaaatgg tattattggt tgctgaaatg gaagagttaa gagctaatcc aaataaaaga
    54001 gcagtaggaa ctgttataga agctgagctt gataaaggaa gagggccagt tgcaacagta
    54061 cttgttcaag gtggtacttt aacagtaggt gacccaatcg ttgcaggtgt tgcatgtggt
    54121 aaagttagag caatgataaa tgcaaaaggt aagagagtaa aaacagcagg accatctaca
    54181 gcagttgaga tattaggtct atcagaagtt ccacaaggag gagaccaatt tgtcgaagtt
    54241 ccaactgata agattgctag aagtgtagca gcaagaagac aacaaatagt tagagatgaa
    54301 atgttaaaat caactcaaag attatcacta gatgctctat ttagtcaaat gagtgaaggt
    54361 tctataaaag accttaatat agttataaaa gcagatgtac aaggttcagt acaggcagtt
    54421 aaacaatctt tagaaaaatt atcaaatgaa gaagttcaag ttaaagtaat acatggtggt
    54481 gttggagctg taacagaatc agacatatta cttgcagcag cttctaacgc aataataata
    54541 ggattcaatg taagaccagt tccaggtgca gaatctctag gagaaaaaga aaatgttgat
    54601 ataagaacat atactataat atacaaggca atagaagata tacaagcggc tatgactggt
    54661 atgttagacc ctgaatatgt tgatgaagaa acaggaaaag ctgaaataag agaaatatat
    54721 aaaatatctg gtgttggaac agtagctgga tgttatgtga ctaatggtaa gatatttaga
    54781 aattgtaaag taagattagt tagagatagc ataataatac atgaaggtga gcttgcagca
    54841 cttaagagat ttaaagatga tgtaaaagaa gttaattctg gatacgaatg tggtatgagt
    54901 tttgtaaatt ataacgacat aaaagaaggc gatatagtag aagcttatat aactaaagaa
    54961 gtagaaagaa aattataaat tcgtatcaaa gaaaatcagt tagtaaagaa ggtcgatggt
    55021 atggcatcat ataatagaac aagaaggata gcagaagaaa taagaaaagt cgtaagtact
    55081 atgcttataa atggagtaaa agaccctaga ataacatcta tggtgagtgt aactgatgta
    55141 gaagttacaa atgacctaag atatgcttat gtatatgtaa gtattctagg tggagatgaa
    55201 gaatccacac taacaggtct taaaagtgct ggaggatata taagaagaga agtaggaaaa
    55261 aatataaaac ttagatatat tcctgagata gtatttaaac ttgatgattc aatagaaaaa
    55321 ggaatgtata tggataacct tataaaaaga gttaatgaaa aaaatgctca acaaaatgag
    55381 gatgaaaatt atgatgaata atatggatag tattataaac tatatttatg agggtgacta
    55441 ttttatagtt acctctcata tcagtccaga tggagacaat attggttcta cactttcaat
    55501 gtattataca ttgaagaatt taggaaaaaa tgtatattat gtacttgatg atgaagctcc
    55561 attaaattta aggtttttgg ttgaaggtgt aaaaatctat aagtctaatg aatttaatat
    55621 gaagaactat tctctaattg cacttgattg tggggataag atgagaatat gtgtgagtga
    55681 tgaaatcaaa aataatgcat caaaattaat ctgtattgac catcatgcta gtaatgattc
    55741 atatggagat ttaaattatg tagatattga tgcatcttct acatgtgaat tagtttataa
    55801 tttattagtt agatttcagc aaataaaaga tattaatatt ataaatgaag atatagcaac
    55861 atgtttatat acaggtcttg taactgatac tggaaacttt tcgtattcaa atgtacatgc
    55921 aagtagcttt gaaatggcaa aaaatttact tgttttaggt gcacaaaaaa atactataat
    55981 acaaaatata tatcaaagca attcttctgg ttattacaaa ttattaggag aagctctaaa
    56041 gggtttggag atatttgatt aaaaaatagt tacgcacact cgtgacttta gtcatgagtt
    56101 agtagctaaa atagtcagca tatagggaaa cttatatgta gagataggat aaaacctatc
    56161 caatactact tgaattgctg
//
LOCUS       DACTZW010000017        56168 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.017, whole genome shotgun sequence.
ACCESSION   DACTZW010000017 DACTZW010000000
VERSION     DACTZW010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 56168)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56168)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56168
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.017"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            7..81
                     /locus_tag="JAM15_05475"
     tRNA            7..81
                     /locus_tag="JAM15_05475"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:39..41,aa:Asn,seq:gtt)
     gene            87..172
                     /locus_tag="JAM15_05480"
     tRNA            87..172
                     /locus_tag="JAM15_05480"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:121..123,aa:Leu,seq:taa)
     gene            188..263
                     /locus_tag="JAM15_05485"
     tRNA            188..263
                     /locus_tag="JAM15_05485"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:221..223,aa:Met,seq:cat)
     gene            271..345
                     /locus_tag="JAM15_05490"
     tRNA            271..345
                     /locus_tag="JAM15_05490"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:304..306,aa:Glu,seq:ttc)
     gene            360..433
                     /locus_tag="JAM15_05495"
     tRNA            360..433
                     /locus_tag="JAM15_05495"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:392..394,aa:Gly,seq:tcc)
     gene            439..514
                     /locus_tag="JAM15_05500"
     tRNA            439..514
                     /locus_tag="JAM15_05500"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:472..474,aa:Val,seq:tac)
     gene            520..596
                     /locus_tag="JAM15_05505"
     tRNA            520..596
                     /locus_tag="JAM15_05505"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:554..556,aa:Asp,seq:gtc)
     gene            607..681
                     /locus_tag="JAM15_05510"
     tRNA            607..681
                     /locus_tag="JAM15_05510"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:639..641,aa:Gly,seq:gcc)
     gene            691..764
                     /locus_tag="JAM15_05515"
     tRNA            691..764
                     /locus_tag="JAM15_05515"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:725..727,aa:Arg,seq:tct)
     gene            1740..2579
                     /locus_tag="JAM15_05520"
     CDS             1740..2579
                     /locus_tag="JAM15_05520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HAT6797713.1"
                     /translation="MLDINSFLNGFFNIILRMSIYDLIDISIVAYIFYKIFMFIKDTR
                     AEQVFKGIIFLLLATQLSNTFKLHTVYWISLKALDYGVIAALIIFQPEFRAGLEHIGR
                     AKFNLFGKNVNTSEETLNRNIEEIVEALYSLSRQKIGALIIMERETRISDIINTGTII
                     DAEISRQLLINIFIPNTPLHDGAVVIRDSKVKAAACFLPLTESKDLSKDLGTRHRAGI
                     GVSEVSDCITLIVSEETGGVSIAKAGKLYRDISRERMMNILRSNLKTNTETRSFFKGG
                     IFK"
     gene            2576..3757
                     /locus_tag="JAM15_05525"
     CDS             2576..3757
                     /locus_tag="JAM15_05525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797714.1"
                     /translation="MINRLKNNTKIKIISFLSAIALWMYVMAVVDPEETKGFEDIPVS
                     ISNMSDLKDKNLVIYPDEKLTADVYIKGSLSKVQSVKKEDIHVYGTIEDPIQGQKEVY
                     LKANIPQGVTLEFKHDVLVVNLEKNIKEKRDIKVEVSGNSKRNINKIELSKEFVDVSG
                     PRTLVKEVKSVRANLDVGNETDDFSKKLQLIPLNSDGTKVEGVTLSSSFVTAKIELLK
                     EKIVPIRVSLNDNKDNDVLKNYKLSKEQVTIKGKKEDIDKISYIKTKPIDLADLANGQ
                     EKEVSLEIPEGITLEDSSITIKLNDTKQLSAEFLYNAGDIELRNIPTNMDNPNVISDV
                     DIKVVVESTEDLSKLNKKDISLYIDLSQGPEEDSKYKIKYETTYQFKKINIEPNIVEV
                     E"
     gene            4061..4963
                     /gene="ptb"
                     /locus_tag="JAM15_05530"
     CDS             4061..4963
                     /gene="ptb"
                     /locus_tag="JAM15_05530"
                     /EC_number="2.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate butyryltransferase"
                     /protein_id="HAT6797715.1"
                     /translation="MRSFEEVIKFAKERGPKTISVACCQDKEVLMAVEMARKEKIANA
                     ILVGDIEKTKEIAKSIDMDIENYELIDIKDLAEASLKSVELVSQGKADMVMKGLVDTS
                     IILKAVLNKEVGLRTGNVLSHVAVFDVEGYDRLFFVTDAAMNLAPDTNTKKQIIENAC
                     TVAHSLDISEPKVAAICAKEKVNPKMRDTVEAKELEEMYERGEIKGCMVGGPFAIDNA
                     VSLEAAKHKGINHPVAGRADILLAPDIEGGNILYKALVFFSKSKNAGVIVGAKAPIIL
                     TSRADSEETKLNSIALGVLMAAKA"
     gene            4985..6064
                     /gene="buk"
                     /locus_tag="JAM15_05535"
     CDS             4985..6064
                     /gene="buk"
                     /locus_tag="JAM15_05535"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HAT6797716.1"
                     /translation="MSKIFKILTINPGSTSTKIAVFDNEDLVFEKTLRHSSEEIGKYE
                     KVSDQFEFRKQVIEEALKEGGVKTSELDAVVGRGGLLKPIKGGTYSVSAAMIEDLKVG
                     VLGEHASNLGGIIAKQIGEEVNVPSYIVDPVVVDELEDVARISGMPEISRASVVHALN
                     QKAIARRYAREINKKYEDINLIVAHMGGGVSVGAHKNGKIVDVANALDGEGPFSPERS
                     GGLPVGALVKMCFSGKYTQDEIKKKIKGNGGLVAYLNTNDAREVEERIEAGDEKAKLV
                     YEAMAYQISKEIGASAAVLKGDVKAILLTGGIAYSKMFTEMIADRVKFIADVKVYPGE
                     DEMIALAQGGLRVLTGEEEAQVYDN"
     gene            6054..6731
                     /locus_tag="JAM15_05540"
     CDS             6054..6731
                     /locus_tag="JAM15_05540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAT6797717.1"
                     /translation="MITNDKRIRIITGHYGSGKSEFAMNYVVKLRDMVSGKVAIADLD
                     VVNVYFRTREKKELMKSLGIQPIDSSINAPTLDLPAVSAEVMSPMVDHSYNSVIDLGG
                     DNVGARVIGRFSHLLKEGDYDMLFVINANREKTQTSEEVIQYIKEIEKSSKLKVTGLI
                     NNTHLIRFTTIDDVLRGQKVAKEVSEKCNIPIRYVACLENLVEQLPKDLEGEIFPIKL
                     YMREDWM"
     gene            6774..6989
                     /locus_tag="JAM15_05545"
     CDS             6774..6989
                     /locus_tag="JAM15_05545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HAT6797718.1"
                     /translation="MAKGKVSFNQERCKGCGLCVEACPVKIIQLDSNVINKKGYNPAT
                     VFEMEKCIGCASCATMCPDVVITVERD"
     gene            7018..8097
                     /locus_tag="JAM15_05550"
     CDS             7018..8097
                     /locus_tag="JAM15_05550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HAT6797719.1"
                     /translation="MAKILMKGNEAFGKAAIEAGCKYFFGYPITPQSELPEYLSRELP
                     KIGGAFVQAESEVSAINMVYGGAGAGARVMTSSSSPGVALKQEGITYAVGAEVPCVVL
                     NVMRGGPGLGSIQPSQADYFMSTRGGGNGDYRTPVFAPATVQEAVDMIMEAFDVADYY
                     RSPVMVVADGMIGQMMEPVEFRAPEKKRELPPKDWATVGTKGKRKPNVINSLYLEPEV
                     LEDHCWHLQEKFDAMEKNEVQYEMYKTEDAEFVFAAYGTTSRVVKSAIDILREEGIKA
                     GLIRPKVLWPFPFEAFNQIPNARNILTVEMSMGQMVEDVKMAVEGKLPVYFHGRPGGM
                     TPTPAEIVEKAKKIIAGELVAGGAR"
     gene            8097..8849
                     /locus_tag="JAM15_05555"
     CDS             8097..8849
                     /locus_tag="JAM15_05555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HAT6797720.1"
                     /translation="MAVVFKKTEGLQDTQTHYCPGCTHGIIHRLVGEVLEELGVLGDA
                     VGVVPVGCSVLGYKYFNCDTQEAAHGRAPAAATGIKRVHPENTVFTYQGDGDLASIGT
                     AEIVHAAARGEKITTIFVNNTTYGMTGGQMAPTTLVGQRATTAQSGRNAETQGYPIRV
                     SEMLATLTGAVFVERVAVDTPAHVRQAKKAIKKAFQVQQAGLGFGIVEVLSTCPTNWG
                     LAPNDALQWLRDNMIPYYPLGNFKNVEVEEVK"
     gene            8850..9407
                     /locus_tag="JAM15_05560"
     CDS             8850..9407
                     /locus_tag="JAM15_05560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:ferredoxin oxidoreductase subunit
                     gamma"
                     /protein_id="HAT6797721.1"
                     /translation="MSTARVICAGFGGQGVMSMGQLLTYAGMLEGKEVSWLPSYGPEM
                     RGGTANCAVTVSNEPVGSPLITDDATAAILLNIPAFEKFKDDVIPGGKIIVNSSLIKE
                     KVDRTDVDVYYIPANELAAELGNDKVANMIMLGAYLKVSDTVDIESVLEAFKKVFGPR
                     KEKFVPLNREALQKGMDATCSKATN"
     gene            9577..10923
                     /locus_tag="JAM15_05565"
     CDS             9577..10923
                     /locus_tag="JAM15_05565"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HAT6797722.1"
                     /translation="MRKYFGTDGVRGVANTELTCDLAYKLGRAGGFVLAQGDHRVKVV
                     VGKDTRISGDMLEASLIAGLMSVGCDVITVGIIPTPAVAYLTRKYGADCGVVISASHN
                     PVEYNGIKFFNKNGYKLDDEIELKIEEYIDDIDKIDCFPIGENVGRKLHEHCAQRDYV
                     DYLKSIISTDFKGLKVVLDCANGASYKVAPIVFDELGASVISINSSPDGNNINYKCGS
                     THPEQLQRAVLEHNADLGLAYDGDADRLIAVNEKGQIVDGDHIMILSALNLKKNNKLA
                     QDTLVVTVMSNIGLTIAAKENGINLSTTAVGDRYVLEDMVKNGYNLGGEQSGHMIFLD
                     YNTTGDGVLSSLILANIILQEKKPLSEIASIMSQYPQVLVNATIKNENKNKYMEYPEI
                     KTEIERIESILDGNGRVLIRPSGTEPLVRVMLEGKEEGQIKELATNLANLIQEKLS"
     gene            11190..13022
                     /gene="glmS"
                     /locus_tag="JAM15_05570"
     CDS             11190..13022
                     /gene="glmS"
                     /locus_tag="JAM15_05570"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HAT6797723.1"
                     /translation="MCGIVGYLGSRKAAEVIVEGLSKLEYRGYDSAGVAVNSSNEEEL
                     NIRKFKGRLSVLAEDLEKNPIDGNLGIGHTRWATHGEPSDVNSHPHFNQAKTIAVVHN
                     GIIENYMEIKEELISEGVKFESQTDTEVIAHLVDKYYEGNLLDAVYKTISKLRGAYAL
                     GVICKEHGNELVAVRKDSPLVVGVGEGENFIASDIPALLKYTRDVYFLENGEVVHLKD
                     ENVTVYDSNRNLVEKEVFHVTWDVEAASKGGYDYFMSKEIHEQPTGVRETLERRLDDN
                     GNIILDSINISKEDLEKINKVYIVACGTAYNAGLLGKYAIEKFVNIPVITDIASEFRY
                     SDPFVDENSLVILVSQSGETADTLAVLRDSKAKGARILSITNVVGSSIARESDDVFYT
                     WAGPEVAVASTKAYTTQITSLYMIALDFAIKKGTITREFYDSMISKMKEIPSKIQEIL
                     DNEEYIKEVAKTVVSSEHAFYLGRGIDYSLAMEGSLKLKEISYIHAEAFAAGELKHGT
                     IALIEKGTPVIAIATQEKLFEKMVSNMEEVRARGAYVVAIAQSHNKDVEKAADKIIYI
                     PNSDDILSPILAVVPMQLLAYHVSVLRGCDVDKPRNLAKSVTVE"
     gene            13474..14769
                     /locus_tag="JAM15_05575"
     CDS             13474..14769
                     /locus_tag="JAM15_05575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase"
                     /protein_id="HAT6797724.1"
                     /translation="MTNDFKKEKKEDYFVNLKAISTEVLQEKVQDNAWVIVDTRLNDA
                     YNGWKLDGVKRGGHIKGAVDFSANWLSVYSDRKDEVLEQALKTKRIDLDKNIVLYDAN
                     GKDALVVADYLSKKGYKYLYKYDIKQWADDENLPMERYKNYQMIVPAFIIKDILDGKI
                     PETFEDSKNIKMIEASWGEESYTKGHIPTSVHVNTDIIEPPPTWMLDNDDNLTKFALD
                     YGLTKDDTVIVSSSTPMASYRLAVILRYIGVKDVRVLNGGTNSWLSAGYELEFISNPK
                     HSCTNFGADIPVNSQLIVTTSELRQKLKEKNKFILVDNRTWDEHIGKVSGYTYYDKKG
                     RIPGALYGHSGSDSVSLEEYRNIDNTMRNKYEILEMWDKENIDVNKQLIFMCGSGWRA
                     AEVLTYANVIGVENTSLYSDGWMGWSLDNSNLIEVGEHK"
     gene            15211..15948
                     /locus_tag="JAM15_05580"
     CDS             15211..15948
                     /locus_tag="JAM15_05580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwmB family TATA-box binding protein"
                     /protein_id="HAT6797725.1"
                     /translation="MKKVKLAISFFILMIIGMTISYADTSINTRYNRLSKALEISEAN
                     FKFYNVKINSVINHNLSNKEFHNIFIEIINNLKLDKKGINWNQKGSGDKIQLCATIKG
                     SDKEISIKGINKNNKESYIVVDILDNKVYKHKEVIYSNVENVLNKYSSQVDVSACIVG
                     EYTKRLQNNKYDDILQKILYNMSAKQIDEVKDVNFLSITAYSKVLNDYELEYLGEKIN
                     LNIGIKYNEDDGKTLIYIATPIIKLDY"
     gene            15969..17222
                     /gene="murA"
                     /locus_tag="JAM15_05585"
     CDS             15969..17222
                     /gene="murA"
                     /locus_tag="JAM15_05585"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002844145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HAT6797726.1"
                     /translation="MAKIIVKKSNPLKGSVKIDGAKNAVLPIIAATLLANGKSTLNGV
                     PNLRDVHVISDLLRHVGAEVEYKENTLTVDASNIKTCEAPYELVRKMRASFLVMGPLL
                     ARFNSTKISMPGGCAIGTRPIDLHLKGFKALGAKIEMDHGFVEAATEKLVGNKLYLDF
                     PSVGATENIMMAASLAEGTTIIENAAEEPEIVDLANFLNEMGADVKGAGTNTIKIKGV
                     KELKGAEHNVIPDRIEAATYMVAAAMTKGDITVENVLMEHLKPVVAKLREAGCEITEM
                     DNSVRVVGPKVLKPIDIKTLPHPGFPTDVQAQFMAMLTVANGTGVVIETVFENRFMHV
                     AEFNRMGANIKIDGRSAVVNGVDELHGAAVNATDLRAGAALILCGLIAEGETQIGEIY
                     HIQRGYVDIDKKITALGGQIEIVED"
     gene            17309..18373
                     /gene="spoIID"
                     /locus_tag="JAM15_05590"
     CDS             17309..18373
                     /gene="spoIID"
                     /locus_tag="JAM15_05590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein D"
                     /protein_id="HAT6797727.1"
                     /translation="MKNPLVVLLGFVTCSVLVPSLITLVSYKNVELTEKPESPVSINK
                     TIKKSDIEDKGNKEEKNTVNYETVNKKAPIINVYNHITGKTEKMDMENYLCGVLAGEM
                     SSEFDIEALKAQSVAARTYVVYKQEHGKSSKHKNAVVCTDYKHCQEYKSYDTLKKLNG
                     EEWIKNKYSKIQEAVRGTKGQIITYNDKAILPLYFSTSSGKTENSEEVFSAKYPYLKS
                     VESPYDKYSPKFASTLKISNTDFVKSLRRAYSTIVIDVNNLSKQVSITKRSDAGTVEK
                     IKLGNKELTGKDIRTVFKLNSANFDIKFGEGYIDFVVKGYGHGVGMSQWGAEGMAEEG
                     YKYYDILSHYYTDTKIKDIY"
     gene            18439..19107
                     /locus_tag="JAM15_05595"
     CDS             18439..19107
                     /locus_tag="JAM15_05595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HAT6797728.1"
                     /translation="MKKKLLEKDGFYLSLFVCVCLLAVGGVWFTNNNVDKLASNKGIM
                     ENANKDSEEEIHLIEKDKKDAIPTATDSKQNLEKAKSKEENKSSTTKLNYIGDKVIRG
                     YSEKEPSYSKTLDVWETHKGVDISCTKGKEVKSLLNGIVVDVFDDEEYGQSVKIKSDN
                     NIVVVYSNLDKNVSVKKEQKVTEGQSLGTVGSTSQIESEEGIHVHLEAYSGEKSIDPM
                     SLIK"
     gene            19205..19465
                     /gene="spoIIID"
                     /locus_tag="JAM15_05600"
     CDS             19205..19465
                     /gene="spoIIID"
                     /locus_tag="JAM15_05600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcriptional regulator SpoIIID"
                     /protein_id="HAT6797729.1"
                     /translation="MRSHIEERAIVVAKYILEKNTTVRQTAKTFGVSKSTIHKDVTER
                     LKEINPSLAKEVKNVLDKNKSERHIRGGLATKLKYEKEHKKM"
     gene            19662..20681
                     /locus_tag="JAM15_05605"
     CDS             19662..20681
                     /locus_tag="JAM15_05605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HAT6797730.1"
                     /translation="MAGADIGIDLGTANVLVYVSGKGIVLEEPSVVAIDKRTDSVLAV
                     GEEAKKMIGRTPGNIVAIRPLRDGVISDYDVTEKMLKSFIDKIVDKKGFGRFFMPRIM
                     VCVPTGVTEVEKRAVEDATRQAGAREVYIIEEPIAAAIGAGVDISQPNGNMIIDIGGG
                     TVDIAVISLGGAVVSESIKVGGDRFDDAIVKYMKKQHNLLIGERTAEKIKFEIGSAFK
                     REEEKYMKITGRNLITGLPSSITINSTEMLEALRECVEQIVVATHAVLEKTPPELAAD
                     IGDVGIIMTGGGSLLYGLDKIIEQRTGITVTIADEPLSCVAKGTGIALGSIDLLETGG
                     SFKRK"
     gene            20697..21125
                     /gene="fabZ"
                     /locus_tag="JAM15_05610"
     CDS             20697..21125
                     /gene="fabZ"
                     /locus_tag="JAM15_05610"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HAT6797731.1"
                     /translation="MLNIDEIKKLIPHRYPFLLVDKITELEVGKRAVGIKNVTVNEPF
                     FQGHFPEYPLMPGVLIVEALAQVCGVAMMSVEENKGKLGVFAGIDKVRIKREVRPGDT
                     LTMEVEMTTLRKNIAKADAKAYVGEELVCKGELMFALVEK"
     gene            complement(21236..21745)
                     /gene="yyaC"
                     /locus_tag="JAM15_05615"
     CDS             complement(21236..21745)
                     /gene="yyaC"
                     /locus_tag="JAM15_05615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protease YyaC"
                     /protein_id="HAT6797732.1"
                     /translation="MYLAKVNYSDDDVIQMLSSVLKTIINENTIVVCIGTDRAIGDTL
                     GPLVGTILKNSNFKYPVYGTLDNPIHALNIYESLDTIKNTHIQGNFLAIDACLGSQSN
                     IGNIQIREGPILPGKGVGKKLPQIGNYSIVGIVDKIDENNKLSFNNIRLSFILDLAET
                     IALALLVST"
     regulatory      21934..22037
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            22174..23367
                     /locus_tag="JAM15_05620"
     CDS             22174..23367
                     /locus_tag="JAM15_05620"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HAT6797733.1"
                     /translation="MARHLFTSESVTEGHPDKICDQISDSILDALLEKDPQSRVACET
                     TVTTGLVLVAGEISTSAYVDIPKLVRETVREIGYTRAKYGFDCDTCAVITSIDEQSGD
                     IAMGVDEGLESKTGEEIEEEIEKVGAGDQGIMFGFACNETPELMPLPISLAHKLSRRL
                     TEVRKTGLVDYLRPDGKTQVTVEYEGSKAVRVHTVLISAQHCETVSNDKIREDLINHV
                     IKEVIPAELLDEETKIYINPTGRFVIGGPQGDTGLTGRKIIIDTYGGYSRHGGGAFSG
                     KDPTKVDRSAAYAARYVAKNIVAAGLADKCEIELAYAIGIARPLSIFIDTFGTGKVSE
                     EKLVELVNKHFDLRPGAIIRDLDLRKPLYKKVAAYGHFGRTDIDLPWERTDKVEQLRK
                     DALGE"
     gene            23683..24780
                     /locus_tag="JAM15_05625"
     CDS             23683..24780
                     /locus_tag="JAM15_05625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797734.1"
                     /translation="MSGKVNIKTVISFAGAYVATVIGSGFATGQEILQFFTFYGYAGI
                     IGGIISMVLFSWFGAEVIDKGRELKLKEPIKIYQVYCGKYLGTFFEWFGPLFLFGTLV
                     IMIAGAGATLSEYYGLNPYVGRIGMAIVSLITVSLGLTRLSKILGNIGPIIIIFTLLV
                     GAISLFSNIDALSNAGNMVDSLNIKTATSNGYFSGVLYTCYNVIIVITFLTGMGASAV
                     NKKDAVWGGIVGGVALMAAAIMMNLALLSDIGNIYTKEIPALYLADKISPIIGILFSV
                     VLLLGIYTTAVPLLWSVTNRFVEDDHPKFKIITIVVSILACIGGLLPFDKLVGTLYPY
                     TGYMGILILLCMLYRRITKTEGYKENKSEIS"
     gene            25044..27263
                     /locus_tag="JAM15_05630"
     CDS             25044..27263
                     /locus_tag="JAM15_05630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HAT6797735.1"
                     /translation="MEKLEGMISEIVFKNEDNGYTIAHLVNENDEIVVVGCMPTLAIG
                     ESIEVEGKWVNHKIYGTQFEVNSFMPVTPSSLEGIYVYLSSGMIHGIGEKMAKRIIDK
                     FGVDTLEVIQNSPEKLQEVEGIGSKKVKQIVKSYEEDRELRNIIIQLSPFGITPNYCL
                     KIYKKYKSSAIEVINKNPYQLAEDIRGIGFKVADSIASKIGIDKNSKDRICQGILYTL
                     NKSLSNGHTYLPEHVLIQDSEKLLELNGEIIKECVMMLVYNQKIHIEKVNNENLIYLM
                     PYYLAENGVCSQIVKLSQYEFEDLKIDIDNEINVLEEDKKIKLAEKQILAVKESVNSG
                     VLIITGGPGTGKTTTINAIIDIFENNGKSVTLAAPTGRAAKRMSETSNKEAKTIHRLL
                     EMGFSTDDDLTFFKDEEDPINSDVIIVDEVSMVDIILMYNLLRAIKLGTRVILVGDSD
                     QLPSVGAGNVLKDMINSNIINVVKLNEIFRQAQESMIIVNAHKINNGEPLYLNTKGKD
                     FFFIRKSTNEEILNEIIGLVNERLPKFYKVDKLKDIQVLSSMRKGELGVTNLNIELQK
                     YLNKKEKFKVEESFSKRLFRVGDKVMQVKNNYTKKWETEDQKESGEGIYNGDIGYVYH
                     IDKDKKTIYILFDQTKIVSYLYDELDEIDHSFCTTIHKSQGSEFPVVVLPIAWAPPML
                     LSRNLLYTAVTRAKKLVVLVGDVKYLEYMIKNNRVNQRYSNLGYKLNKFKQEGLLIE"
     gene            27266..28048
                     /locus_tag="JAM15_05635"
     CDS             27266..28048
                     /locus_tag="JAM15_05635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HAT6797736.1"
                     /translation="MKICNDNFIKNFKNMINKCLDFIYPENISCIICDKSIKKTNTYS
                     ICKSCFKEMNFIQDGCMKCGKPIIRHSIEKEFIEECSYCFNKDFYFDKSISCIEYNDV
                     TKKMVLGLKYNQKTFMAKYIAQIMKEKLYLENIKFDYILFVPLHKKRLNKRGFNQAQK
                     IAFNLSKIVNIPLLDCISRKKYTRMLYKLNKKERKEELKNVFVVKENVKLINNKNILL
                     IDDIFTTGLTTNEISKLLKLSGANKVFVLTLLTKANDNYIME"
     gene            28389..30293
                     /locus_tag="JAM15_05640"
     CDS             28389..30293
                     /locus_tag="JAM15_05640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HAT6797737.1"
                     /translation="MNKRQENLLTTLLLKEEFINVNKIANDFECSERTIRNDCKYIDE
                     WLSTFCNAYIKRKPNIGIKFSGDGTDKILVNQKLRGEVKRVNSELHKQVEILNLLLCN
                     NKKVTLNDLSNKLYINKNIVREEISKLSVALNNYNLNISTKKGSGIYIEGDEKDIRIM
                     LVSFLFKYIDKYRLNIDEIEHFHIVDIIIVKNIMLTIEEDMDIRLTDISFKQLMLFLL
                     INIIRIRLGNSLKVSNTKKELKLKMLILDIEDELKSNLSIVLNYEEKLFIESLILGMN
                     KQINNNNIKKSLYLNEELASYTKKIINLVSEESGINFNNDILLYEQLICHLNVTMHQM
                     KSNVYLENPLLDNIKTKFCFLFTVISSSIEIELKGKQITEDEIGYLTLHFQTSLERKY
                     SKRESNKKASIVCPFSFGVSMLLKVKIEKRFDNIKIIETLREEDLKRDNFNKTIDFII
                     AFQEYENIQKPIFITTPLFTDEDENKLKEFTNKIKEKDTSYKLMNRLMMSDYLIRELE
                     HDDIYEAITYLTNLLIEKHYAEKEYLQSIITREKSYPTNVGKGILFPHGDMKYIKQSV
                     LCFARLKTPIKIRNGKDIKIILLLAYKKDDDRKVFRELFKEISNLTEDENMLDILSKC
                     DIEKVKDILI"
     gene            30434..30742
                     /locus_tag="JAM15_05645"
     CDS             30434..30742
                     /locus_tag="JAM15_05645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAT6797738.1"
                     /translation="MEEIVLKIIIHAGNAKSMLYEALDYAKENDFKKADELIENANEE
                     ILKAHKVQTELIQKEAGGDKSDISILLIHSQDHLMTCMSERNLIKEMIMLRKEIQKLK
                     "
     gene            30765..31091
                     /locus_tag="JAM15_05650"
     CDS             30765..31091
                     /locus_tag="JAM15_05650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAT6797739.1"
                     /translation="MKRKVYLFCSFGMSTSLLADKMQKVADEHNLPIEVEAFPIAEID
                     KIVEEKNPDCILLGPQVKYMLKELKPKFEAQGKLIDIINEVDYGTMNGEKVLKLAIKL
                     IKSKQA"
     gene            31130..32464
                     /gene="celB"
                     /locus_tag="JAM15_05655"
     CDS             31130..32464
                     /gene="celB"
                     /locus_tag="JAM15_05655"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HAT6797740.1"
                     /translation="MNRLERILMPLAEKIGKNKLLIAIRDGFLVSSPLLIIGSLFLLV
                     ANFPIKGWNEFVGQIFGPDWAVKLQQPTVATFEVMTLLAVLGIGYSYAKQIDVDPIAS
                     AAVAIVAFFIITPFVIPYTPEGTESVYMVTGIPLGWMGSKGMFVGMITAITSVKLFAA
                     VVKKGWTLKMPDGVPPTVSKSFAALIPSAIVMVVFFLVKIAFEATPYGSIHEFIFKFL
                     QMPLLKLGNSLGAMAIAYIFLHLFWFFGINGSSVVGAVYNPILKILSAENLAAFQAGS
                     KIPNIITGQFQDMFATFGGAGSTLSLVIAMLLICKSKRIKSMGKLSILPGIFGINEPL
                     IFGLPIMLNPILLIPFAIVPTINIIIAYFCMSAGLVPLTNGVQLPWTTPIIFSGFLTT
                     GWQGAVLQLVLLILGIFMYIPFIKMLDKQYLREENETVEEEDDDISFDDLVL"
     gene            32475..32996
                     /locus_tag="JAM15_05660"
     CDS             32475..32996
                     /locus_tag="JAM15_05660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/betaine/sarcosine/D-proline family
                     reductase selenoprotein B"
                     /protein_id="HAT6797741.1"
                     /translation="MKKIVMILDQIQAGAGGKEKSNIPPAGKSSPLGPGVMMDPFLNE
                     SKVIATLFCGDEFFVNNQEEVTSKMIAMVKKLNPDVVICGPSFNYENFSKMSAILSKN
                     INDKTDIPAFAAMSEENIDVINEYKNDICIVKTPKKGGIGLNDSLNNICKLAKAIANK
                     EDITLMKEEFCYQ"
     gene            33089..34048
                     /locus_tag="JAM15_05665"
     CDS             33089..34048
                     /locus_tag="JAM15_05665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase"
                     /protein_id="HAT6797742.1"
                     /translation="MWGMIATWRMALEGITEASEHLEKGMEAGDAVELAVRRVEDYPF
                     YKSVGYGGLPNENCEVELDAAFMDGNTLDIGAVAGIRDYSNPVSIARKLSYEKVNNFL
                     VGIGAEDYAHKNGFERKNMLTDRAKLHYKKRKKETLDKGLSPYAGHDTVGMISLDKTG
                     KMCAATSTSGLFMKKRGRIGDSALSGSGFYVDSSIGGATATGLGEDLMKGCISYEIVR
                     LMKEGKHPQEACDIAVNELDKQLIKRRGKAGDLSLVAMNNKGEWGVATNIADFTFSVV
                     TKEESPTVYISNRVDGKTIHKVISNEWMEAYEARIKAPIEVSE"
     gene            34097..35149
                     /locus_tag="JAM15_05670"
     CDS             34097..35149
                     /locus_tag="JAM15_05670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HAT6797743.1"
                     /translation="MNIISNKIDELKEDLLSDIIDIVKIPSVKGESENGFPFGEKVGE
                     ALNKALEISEKLGFKVRNLDNYIGYAEHGDSDDYVCVIGHVDVVHEGDGWKHQPYKGE
                     ETNGRIYGRGVLDNKGPIMSALYGLYAIKELNLKLDKRVRIIFGTNEESGFGDIPYYL
                     EKEKAPIMGFTPDCKYPVVYGEKGMAKIRIKSKINYEEDVYLGFIENMSENVLVTYKE
                     LNIENSDTILDIKVKYDFSYKLKDVLDEIKASFPNSIDIEVISNFNPVYFDKESNLVK
                     KLQLAYERVTSLDGTPVTTNGGTYAKVMPNIVPFGPSFPGQKGIAHNPDEYMDIEDII
                     LNAKIFANAIYELAKE"
     gene            35152..35826
                     /locus_tag="JAM15_05675"
     CDS             35152..35826
                     /locus_tag="JAM15_05675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HAT6797744.1"
                     /translation="MLEIIGMSVEDAKIIEDCGADRIELVSALTEGGLTPSFGLIESV
                     VNSVKIPVNVMIRHHAKSFVYSKEDISIMQRDISVVKEIGANGVVFGVLDKNSSIDEK
                     NLNVLLKCCDNLDVTFHRAIDESNTIDSVKILKDYDKITNILTSGGKGSIVDNIQMIK
                     NMMLSSNHIKILLGGGLNFNNIEKIKELTKASNFHFGTAIRINNSPFEDIDRQKLKQL
                     VNIISR"
     gene            36379..36930
                     /gene="raiA"
                     /locus_tag="JAM15_05680"
     CDS             36379..36930
                     /gene="raiA"
                     /locus_tag="JAM15_05680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HAT6797745.1"
                     /translation="MNIIISGKQIELTDAIKNKIETKLSKLDNYIHPDTDVKVTVSAR
                     KARQKIEVTIATVNGPIIRAEDMQENLYTAIDVVYDKLSKQLKKYKKRLQDKHKDNKS
                     IRFQDAEINLADEQEDYGDENQELVIQRRKKFSVKPMSEEEAVLQMELIGHDFYMFKN
                     IDSDEIAVVYKRNNGGYGIIEHE"
     gene            37062..39737
                     /gene="secA"
                     /locus_tag="JAM15_05685"
     CDS             37062..39737
                     /gene="secA"
                     /locus_tag="JAM15_05685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019595423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HAT6797746.1"
                     /translation="MSFMDNLFNMADKKELKKFNKTVDIIDSLEPKFESMADSELKNM
                     TNIFKERLANGESIDDILPEAFAVVREVSKRVLGLRHYRVQMIGGIVLHQGRIAEMKT
                     GEGKTLVATAPVYLNALTGKGVHVVTVNDYLAKRDRDQMAKIYEFLGMSVGVIIHGQN
                     PKVRKEQYDCDITYGTNNEYGFDYLKDNMVIHKEQRVQRGLNYAIVDEVDSILIDEAR
                     TPLIISGPGDKSTHLYSDANTFVLTLKPDDYELEEKDKAVSLTASGIQKAEVYFNVDN
                     ITDISHTELYHHINQALRAHVIMKKDVDYVAKDGEIVIVDEFTGRLMFGRRYSEGLHQ
                     AIEAKEGLKIQRESKTLATVTFQNYFRMYKKLSGMTGTAKTEEEEFKAIYKMDVFQVP
                     TNKLMVREDLPDSVYKSEIGKFNAVAQEIIERHKVNQPILVGTVSIEKSELLSQILKK
                     KGIKHEVLNAKHHDKEAEIIAQAGRLGAVTIATNMAGRGTDIVLGGNPDFLTKREMRR
                     NGFKEEIVNRVDTPIEGIPVKGNEILFEAREEYEKLFEKFKQQTQEEQKQVVEAGGLA
                     IIGTERHESRRIDNQLRGRAGRQGDPGSSRFYIGLDDDLMRLFGSDRISGIVDKIGLE
                     EDMPIEHRILSKSIEGAQKKVEGKNFGIRKHVLQYDDVMNKQREIIYAERKRVLEGED
                     LQEQIQSMTHSIIEEAVTLYTQDKGFDEEGFKEHMYNLFLPKGSIEIPEIEKLNPVEI
                     TEKVYEIAMKIYTSKEEQVGYERMREVERVILLQAVDNHWIDHIDAMDQLRQGIGLRA
                     VGQQDPVIAYKMEGFDMFDEMNKHIKEDTVRYLFNITIETPVERKAVVDVENLSSPSD
                     GTLPTSKTVKKDEKVGRNDLCPCGSGKKYKNCCGR"
     gene            39843..40859
                     /locus_tag="JAM15_05690"
     CDS             39843..40859
                     /locus_tag="JAM15_05690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019106901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HAT6797747.1"
                     /translation="MKNIQINEEKMNQQDFWNDNEVAQRVLQENKSLKEILEEYESLK
                     SLLEDIEVLIEIGLEEDDDSVERDIEKSIESMEEKLSEMKIKTLLNGEYDKNNAILSI
                     NAGTGGLDAQDWAQMLLRMYIRWSESKGYKVKLLDIISDPEAGIKTATILVEGTNAYG
                     YLKSEKGVHRLVRISPFDPSGKRHTSFASIDVTPELDENIEVEINPSDLKIDTYRASG
                     AGGQHVNTTDSAVRITHIPTGVVVQCQNERSQHLNKDRAMRLLMAKLIELKELEQKEK
                     IEDIQGKYSQITWGSQIRSYVFQPYKLVKDHRTNAEFGNVDSVMNGNIDLFINEYLKM
                     NKIV"
     gene            41003..43144
                     /locus_tag="JAM15_05695"
     CDS             41003..43144
                     /locus_tag="JAM15_05695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HAT6797748.1"
                     /translation="MDINQILKKEFNLRDEQINNTLKLIDEGNTIPFIARYRKEMTGE
                     MSDVTLREFYEKLMYLRNLQSRKDDVVRLIDEQGKLTDEITQNIEKAKTLQEVEDIYA
                     PYKQKKRTRATIAKEKGLENLALSILENNLDNIEIEAKNYLDEEKEVLSIEDALKGAR
                     DIIAELVSDDAKIRKYIRELALREGMIVSKSATDEKSVYDMYYDYSEAVKSMAPHRVL
                     AINRGEKESFLKVKLEINNDKVLNYIINEYVNSKNFKNKEEIVSSIEDSYKRLIFPSI
                     EREIRNHLTEIAQERAISVFGKNVKSLLLQPPVKDKVVMGFDPAFRTGCKIAVVDKNG
                     KLLDYTTVYPTDPQNDVEGAKKVLKGLIEKYDIDIISIGNGTASRESETFVSEMIKEI
                     DSEVQYVIVSEAGASVYSASELADEEHPDINVSIRGAISIARRLQDPLAELVKIDPKS
                     IGVGQYQHDLNKKRLEEVLDGVVEDSVNSVGVDLNTASYSLLEHVAGISKAIAKNIIA
                     YREENGDFTSRAQLKKVKRLGPQAFTQCAGFMRILEGKNPLDNTGVHPESYDICKKMI
                     EIIGYSLDDVKNKNIGEIDEKIKEIGLRELSEKLEVGQVTLKDIIAEIKKPGRDPREE
                     GIKPILRTDVLKIEDIQEGMTLKGTIRNVVDFGAFVDIGIKNDGLVHKSEMSNSFVKD
                     PMSIVTVGDIVDVKVIGIDLNKKRVALSMKK"
     gene            43292..44458
                     /locus_tag="JAM15_05700"
     CDS             43292..44458
                     /locus_tag="JAM15_05700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HAT6797749.1"
                     /translation="MIFIKNGKINTITNGIIHGDILIDEGKIIEIGEDLIAPLDVEVI
                     DASNKLVFPGFIDAHTHLGLWEDGIGFEGADGNEETDPITPQLNPIDGINPMDRTFKE
                     AFEGGITSVCTTPGSANVMGGQCIAIKTCGKRIDKMVIKNPVASKIAFGENPKSCYGQ
                     DDKSPQTRMAIAALLRENLKKAEEYLEDIDMYESHDDEDCEKPEYDIKMESLIPVLRR
                     EIPFKAHAHRADDMFTAIRIAKEFNLKLTLDHCTEGHLIVDELVEEGFPVIVGPSLSE
                     RSKFELRNLTFNTAGILSNAGLDVCIMTDHPVIPVQYLPICAGIAVKHGMKEEKAIES
                     ITINPAKALGIEDRVGSIEVGKDADLVIWDNSPLEIQSNVLYTIINGKVVYEKK"
     regulatory      44518..44635
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            44760..45365
                     /locus_tag="JAM15_05705"
     CDS             44760..45365
                     /locus_tag="JAM15_05705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAT6797750.1"
                     /translation="MQNTAKRGNMISTRTLVVMSILSAISYLLMFIQAPIPGIFPDFL
                     KIDLSDIPAIFGGMSLGPLVGFGIVVVKNVLQAITATTTGGIGEFANILIGGSYVMIL
                     CYSYKRSGDLKGVLIGFVLGTISMTIIGSLVNYFVMLPLYGQLMGLDAIIGLGSAINP
                     QVHDLFTFVIWMIAPFNVLKAVIISLVTLPLYKKMGNIIKK"
     gene            45694..46734
                     /locus_tag="JAM15_05710"
     CDS             45694..46734
                     /locus_tag="JAM15_05710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HAT6797751.1"
                     /translation="MHLSKKIKKLFLDDKGYYFNSNWKDIHIGIYDTKLGDSLKYITN
                     EYIENMERVKYDYRELKNIENQTDGMCILAIRQNYKALEYVKNQTEELCLEAIKYNYK
                     ALEYVKEQTEYLCLEAIKKDCNALKYVLNKTEGLIIKAISHSSNIDVVSILKALETQT
                     RRICLEAIKKDGRCLAYVREQSEELCIEAIKQNYKALKYVKNQTEKMCIESVRQNGMA
                     LQYVNKQTDKICIEAVKQDGRSIQFVNNKTEEICINAIRYLNKKYNIKDVLSYIDKYT
                     EDICIEIVRQNGKMLMYIKNQTEKMCIEAVKENYKSLKYVKEQSERICKEALKQNHKA
                     KEYVKIAIDDCI"
     gene            46873..47325
                     /gene="tsaE"
                     /locus_tag="JAM15_05715"
     CDS             46873..47325
                     /gene="tsaE"
                     /locus_tag="JAM15_05715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HAT6797752.1"
                     /translation="MAKIYLENENKTREIGYKLGKLLKEGSVICLVGDLGAGKTTMTQ
                     SLADSLGIEDYITSPTFTIINEYEGKIPLYHFDVYRIGSSDEMYDIGYDEYVNSNGIC
                     IIEWANLIEDILPKEYLNIELRYKDEGREMILTPKGEFYKEIVEELIK"
     gene            47325..48041
                     /gene="tsaB"
                     /locus_tag="JAM15_05720"
     CDS             47325..48041
                     /gene="tsaB"
                     /locus_tag="JAM15_05720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HAT6797753.1"
                     /translation="MKILGMDTSSMAASVAVVEDDNLICEFTVNNKKTHSQKLMPMIE
                     NMLSMSDLSIKDMDLLAVCIGPGSFTGLRIGMATVKAMAHVNNIPIIAVNSLESLANN
                     INFCDRKICCILDAQKNQVYSAKYKFENGEMIELDGVDVVEFDALVDEIVSTNEEFII
                     VGEAVYKYKDKLENIKNIKIPSPANNVSNAGSLCSLALNKYNKNIDVHTCYTINPMYI
                     RKSQAEVQYDEKMKRLNNGR"
     gene            48031..48507
                     /gene="rimI"
                     /locus_tag="JAM15_05725"
     CDS             48031..48507
                     /gene="rimI"
                     /locus_tag="JAM15_05725"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HAT6797754.1"
                     /translation="MEDNTKLIVDDIKIEEMTTEDIDEVFEVEKNCFEDYWSKESFRK
                     ELSNEVARYIVAKLNGKIVGYVGIWLILDEGHINNVAVHSDYRGKKIGDKLIKGIVDL
                     CKDNNIASMTLEVRASNKIAQNLYRKYGFKMGGIRKEYYSDNKEDAIIMWNQLKEV"
     gene            48513..49529
                     /gene="tsaD"
                     /locus_tag="JAM15_05730"
     CDS             48513..49529
                     /gene="tsaD"
                     /locus_tag="JAM15_05730"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002845766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HAT6797755.1"
                     /translation="MSDIITLAIESSCDETAASVLKNGREILSNIISTQIETHKKFGG
                     VVPEVASRKHVENIDIVVQEALDKANIGFNDIDHIAVTYGPGLVGALLVGLSYAKALA
                     YTLNIPLVGVNHIEGHLSANYIEHKDLKPPFITLIVSGGHTHLVEVKDYGKYEILGKT
                     RDDASGEAFDKISRAMNLGYPGGPIIDNLAKNGNKHAIEFPRAYLEEDSYDFSFSGLK
                     SSVLNYLNGKRMKNEEIVVEDVAASFQEAVVEVLSTKALKAVKDKGYNIITLSGGVAS
                     NSGLRAKITELAKDNGITVKYPPLILCTDNAAMIGCAGYYNFINGKTHDMSLNAVPNL
                     KINQ"
     gene            49826..52534
                     /gene="hpdB"
                     /locus_tag="JAM15_05735"
     CDS             49826..52534
                     /gene="hpdB"
                     /locus_tag="JAM15_05735"
                     /EC_number="4.1.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase large
                     subunit"
                     /protein_id="HAT6797756.1"
                     /translation="MSQSKEDKIRSILEAKNIKSNFQNKENLSEFNEKKASKRAEDLL
                     DVYYNTLSTADMEFPYWYNREYRKSDGDIPVVRRAKALKAAFSHMTPNIIPGEKIVMQ
                     KTRHYRGSFPMPWVSESFFVAQGEQMREEAKKLASNTADELTKFGSGGGNVTESFGNV
                     VSIAGKFGMRKEEVPVLVKMAKEWVGKSVEDLGFHYEKMMPDYDLKENLMSTLICMFD
                     SGYTLPQGREVINYFYPLNYGLDGIIEMAKECKKAVAGNASGDGLIGMDRLYFYEAVI
                     QVIEGLQTWILNYAKHAKYLESIETDLEAKKEYSDLVEILEHIAHKQPRTFREALQLT
                     YTIHIASVNEDAISGMSIGRFGQILYPWYEQDIEKGLITKEEVIELLELYRIKITCID
                     CFASAGVNGGVLSGNTFNTLSIGGLKEDGSTGANELEELLLEASMRCRTPQPSLTMLY
                     DEKLPEDFLMKAAECTKLGSGYPAWVNNSNGTTFMMKQFADEGMTVEEARAFALGGCL
                     ETSPGCWKQLTLNGKTYSIAGGAGQSAGSGVHFIANPKILELVLMNGKDHRMNIQVFE
                     PHNKPLDTYEEVIEVFKDYYKQAINVLERANNIELDIWRKFDTSIINSLLKPDCLDKG
                     QHIGNMGYRYNATLNVETCGTVTMVNSFAALKKLVYDDKAFTIEEMKDAILNNFGFKD
                     ALEVGNYSMADQVKVDKTGKYDAIYKACLDAPKYGNNDLYADNILKNYEVWLSKVCEE
                     AQSLYAKKMYPCQISVSTHGPQGAATLATPDGRLSGTTYSDGSVSAYAGTDKNGVYAL
                     FESATIWDQAVVQNSQMNLKLHPTTIKGQQGTKKLLDLTRSYLRKGGFHIQYNVVDSE
                     TLKDAQKNPDNYRQLMVRVAGFTQYWCELGKPIQDEVIARTEYEGV"
     gene            52538..52795
                     /gene="hpdC"
                     /locus_tag="JAM15_05740"
     CDS             52538..52795
                     /gene="hpdC"
                     /locus_tag="JAM15_05740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase small
                     subunit"
                     /protein_id="HAT6797757.1"
                     /translation="MRKHSDCMNFCAVDATKGICRLSKQMINLDDAVCPEIKVMPKCK
                     NCKNFVEANDEGIGKCVGLEKEDWVYSTLNAITCEGHVFNE"
     gene            52788..53738
                     /gene="hpdA"
                     /locus_tag="JAM15_05745"
     CDS             52788..53738
                     /gene="hpdA"
                     /locus_tag="JAM15_05745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase activase"
                     /protein_id="HAT6797758.1"
                     /translation="MSSQKQLEGMIFDVQSFSVHDGPGCRTTVFLNGCPLSCKWCANP
                     ESWTVRPHMMFSELSCQYENGCTVCHGKCKNGALSFNLDNKPVIDWNICKDCESFECV
                     NSCYYNAFKLCAKPYTVDELVQVIKRDSNNWRSNGGVTFSGGEPLLQHEFLHEVLLKC
                     HEVNIHTAIETSACVSNEVFNKIFKDIDFAFIDIKHMDREKHKEQTGVYNDLILENIS
                     NLANSDWNGRLVLRVPVISGFNDSDENISDIISFMHKNNLVEINLLPFHRLGESKWTQ
                     LGKEYEYSDKGDVDEGHLEELQDIFLDNGIACYVGHETAF"
     gene            54045..55007
                     /locus_tag="JAM15_05750"
     CDS             54045..55007
                     /locus_tag="JAM15_05750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAT6797759.1"
                     /translation="MNKSWSNLIIKNKDRKVRSGWIIIAVMATFYILQYYLSMTLVEI
                     IRKILIATGDINLKTNYFSEYANWVSDVGLQVVFQILTDSLMIIIPIIVWRFIMKNPI
                     SEMGLHSYRIKKKEGYVGMLLGIFNCTVIFIITITIGGGHVTSWVPKISPLTVSWILV
                     FILVAFAEEILNRGFFMAVLRRCKNIYFIMIVPSVIFGLIHIWNPDVTFLSVINIIII
                     GILFSYMFIKSSNIWMCIGYHFTWNVFQGIIYGMPVSGLQVPGIITTQITNSNLLNGG
                     MFGIEGGILTTFVNLLSFIFVWYYYRDSKYDFVSDKVNVTNIKN"
     gene            complement(55106..56086)
                     /locus_tag="JAM15_05755"
     CDS             complement(55106..56086)
                     /locus_tag="JAM15_05755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAT6797760.1"
                     /translation="MNLKLIWINILNPVFIKNEIKRKKIQIIIFFFINFGLTYSLGLL
                     LYYNKFIDPENFASFMMILPLSSVAIAKFYTEGLNNDMYEFYSLIILFFFIYSLLIVL
                     KLLNLINNNEFIIINLILTFISSLSIIIYSSNKKNLYPVKNIKLGSLLIIYFMISVIV
                     PTSFILILQGAQPNYSGIIKFIFTPITSLTTIYIFFSEEYAWRGFLQNIFFDKFGKKL
                     GVIILGMCWSLWHLPLIFTLYTPEAPILGVILRSIHIVGISIFLGYLYMKTKNIWFCA
                     IIHVLNNSAFLITNSKESTITYHDILIVSMVVLIFYVPFLFTKEYKNNLE"
BASE COUNT        22504 a         6057 c        10644 g        16963 t
ORIGIN      
        1 aaatgttcca aggtagctca acggtggagc aaccggctgt taaccggtag gctgtgggtt
       61 cgagccccac ccttggagcc aaaaaagccg aagtggcgga actggcagac gcacaggact
      121 taaaatcctg cgggacttac ctctcgtacc ggttcgattc cggtcttcgg cacttataaa
      181 acaatatcgc ggggtggagc agttggcagc tcgtcgggct cataacccga aggtcgtagg
      241 ttcaagtcct gcctccgcaa ccattaaaac ggctcgttgg tcaagaggtt aagacaccgc
      301 cctttcacgg cggtaacagg ggttcaattc ccctacgagt caccaattca attaaatatg
      361 cgggtgtagc tcaatggtag agttctggcc ttccaagcca gctgtgaggg ttcgatcccc
      421 ttcacccgct ccaaaaatgg gaccatagct cagctgggag agcacctgcc ttacaagcag
      481 ggggtcacag gttcgagccc tgttggtccc accattcgcg gcctggtagt tcagttggtt
      541 agaatgccag cctgtcacgc tggaggtcga gggttcgagc cccttccagg tcgccaaatt
      601 aaataagcgg gaatagttca gtggtagagc gcaaccttgc caaggttgaa gtcgcgagtt
      661 cgaatctcgt ttcccgctcc ataataactt gggtgcatag ctcagctgga tagagcaacg
      721 cccttctaag gcgtgtgtcc ggggttcgaa tccctgtgcg ctcattaaga aaagtttact
      781 ataaattata gtaaactttt atattgttta aaaagacaca ggaaacatgt atattacctg
      841 tgtcttttta tttataaact ttaaactatg taaaaatcac agtatattct aatagagtta
      901 cagtatattc attaatattg taaacatacg gagggtaatg tataatagtc tacaagatgt
      961 ttatgaaggc accagttaaa tataactaat tatataagag ttatatacat tatattgtat
     1021 actttatggt atttatatat tgaaataact tatgaaatta tttataaaga gattcatgag
     1081 catatttttg tctaaacaat aagtataaga aattataaaa aattagagac tatagtgaat
     1141 tgacaattta atgtaatatt tataagttat actaagtaaa ttattatact gtgaaatgga
     1201 tatataactt taggtattgt gtattatttt cactgtagga gattatatct agttatacat
     1261 aataagtttt aatgatagtt tatagtaaga tattaaaata aatttatcta atctagatat
     1321 gaaataagtt attactttaa tataaaaatg aatctaatgt aataatattg atgataagta
     1381 atatttagat tttgtatttg tttatagtta ataagtggat tatagaattt ataataatta
     1441 atatatatta aacaaagata tattaagata ttttagaaca taaaactgca ttaaggcgcg
     1501 agtactattt tgtattcgcg ccttgatggt ttgagttatt tgagtaaaaa ctaactttaa
     1561 taagaaatat gtatttatta agttgatatt tttaatgtgt ttagagatta tttaacaatc
     1621 tccaaatata aaactagaat tatttacata aaagttaaat agtttgtata gagttagatt
     1681 tatatagtat aatacttagt gtaaataatt aagaagttat caaacaggag gataaaactg
     1741 tgttagatat aaattctttt ttaaatggat tttttaatat aatattaaga atgagtatat
     1801 atgatttaat tgacatatct atagtagcgt atatttttta caaaatattt atgtttataa
     1861 aagatacaag agcagaacaa gtgtttaaag gtataatatt tcttttatta gcaactcaac
     1921 ttagtaacac ctttaaattg cataccgttt attggatatc tcttaaggct ttagattatg
     1981 gagttatagc tgctcttata atttttcaac cagaatttag agcaggactt gaacatatag
     2041 gaagagcaaa gtttaattta tttggaaaga atgtaaatac ttctgaagaa actctcaata
     2101 gaaatataga agaaattgta gaagctttat attcactttc tagacaaaaa ataggagctc
     2161 ttatcataat ggagagagaa actagaataa gtgatataat aaatacagga actattattg
     2221 atgctgaaat ttctaggcaa ctattaataa atatatttat accaaataca ccattacacg
     2281 atggagctgt tgtaattaga gattctaagg taaaagcagc tgcatgtttt ttgccattga
     2341 cggaaagtaa ggatttaagt aaagatttgg gtactagaca tagagcagga ataggggtaa
     2401 gtgaggtgtc tgactgtata actctgattg tatcagagga aacaggtggc gtatcaattg
     2461 ctaaagcagg taagttatat agagatattt ctagagaaag aatgatgaat atattacgta
     2521 gtaatttaaa aacaaataca gaaacaagaa gttttttcaa aggtggtata tttaaatgat
     2581 aaatagacta aaaaataata ccaaaataaa aataatatca tttttaagtg caattgcatt
     2641 atggatgtat gttatggctg tagttgaccc tgaagaaact aaagggtttg aagatatacc
     2701 tgtatctata agtaatatga gtgatttaaa ggataaaaat cttgttatat atccagacga
     2761 aaaattaaca gcagatgtat atataaaagg tagtttatca aaggtacaaa gtgttaagaa
     2821 agaagatata catgtatatg gaaccattga agacccaata caaggacaga aggaagtata
     2881 tttaaaagca aatattcctc aaggtgttac tctagaattt aagcatgatg ttttagtagt
     2941 aaatcttgaa aaaaacataa aagaaaaaag agatataaag gtagaagtaa gtggaaattc
     3001 aaaaagaaat ataaataaaa ttgaacttag taaggaattt gtcgatgtat caggtccaag
     3061 aactctagtt aaagaagtca aaagtgtaag agctaatcta gatgttggta atgagacaga
     3121 tgatttttct aaaaaattgc aattaatacc attaaatagt gatggaacta aggttgaagg
     3181 agtaacatta agttcatcct ttgtgactgc aaagatagaa ctattgaagg aaaaaattgt
     3241 cccaataaga gtaagtctaa atgataataa agataatgat gtactgaaaa actataaatt
     3301 aagtaaggaa caagttacaa taaaaggaaa gaaagaagat atagacaaaa taagttatat
     3361 taagacaaaa cctattgact tagctgattt ggccaatggt caagaaaaag aagttagctt
     3421 agaaattcca gagggtataa ctcttgagga tagctctata acaattaaat taaatgatac
     3481 aaaacaattg agtgcagaat ttttatataa tgcgggagat attgaattaa gaaatatccc
     3541 aacaaatatg gataatccaa atgtaatttc tgatgtagat ataaaagttg ttgtagagtc
     3601 aacggaggat ttgagtaagt taaataaaaa agatatttca ttatatattg atttatcaca
     3661 aggccctgag gaagatagta aatataaaat aaaatatgaa acaacatatc aatttaaaaa
     3721 aataaatata gaacctaata ttgttgaagt ggaatgaaca aatatttcga atatttagtt
     3781 gttacaagat gcgacaaaaa aacctataaa attaagtttg ttaattttat gtttttgttg
     3841 catcttgttt attttagtta tattataaaa taaggacaat gagatatttg ttaaatctaa
     3901 aaagcgctag atatatgaaa aaagactgat aaatagattt aaataaatat tttgaattaa
     3961 atatttcaat tatctctagg aaaacgttgc tgaacgagtt ataatttaat tgagatataa
     4021 aaagttctat ttcaaaaaat tcaagatgag gtggaaatgc atgagaagtt ttgaagaagt
     4081 aattaagttt gcaaaagaaa gaggacctaa aactatatca gtagcatgtt gccaagataa
     4141 agaagtttta atggcagttg aaatggctag aaaagaaaaa atagcaaatg ccattttagt
     4201 aggagatata gaaaagacta aagaaattgc aaaaagcata gacatggata tcgaaaatta
     4261 tgaactgata gatataaaag atttagcaga agcatctcta aaatctgttg aattagtttc
     4321 acaaggaaaa gccgacatgg taatgaaagg cttagtagac acatcaataa tactaaaagc
     4381 agttttaaat aaagaagtag gtcttagaac tggaaatgta ttaagtcacg tagcagtatt
     4441 tgatgtagag ggatatgata gattattttt cgtaactgac gcagctatga acttagctcc
     4501 tgatacaaat actaaaaagc aaatcataga aaatgcttgc acagtagcac attcattaga
     4561 tataagtgaa ccaaaagttg ctgcaatatg cgcaaaagaa aaagtaaatc caaaaatgag
     4621 agatacagtt gaagctaaag aactagaaga aatgtatgaa agaggagaaa tcaaaggttg
     4681 tatggttggt ggaccttttg caattgataa tgcagtatct ttagaagcag ctaaacataa
     4741 aggtataaat catcctgtag caggaagagc tgatatatta ttagccccag atattgaagg
     4801 tggtaacata ttatataaag ctttggtatt cttctcaaaa tcaaaaaatg caggagttat
     4861 agttggggct aaagcaccaa taatattaac ttctagagca gacagtgaag aaactaaact
     4921 aaactcaata gctttaggtg ttttaatggc agcaaaggca taattttaag ggggaaatag
     4981 gcaaatgagc aaaatattta aaatcttaac aataaatcct ggttcgacat caactaaaat
     5041 agctgtattt gataatgagg atttagtatt tgaaaaaact ttaagacatt cttcagaaga
     5101 aataggaaaa tatgagaagg tgtctgacca atttgaattt cgtaaacaag taatagaaga
     5161 agctctaaaa gaaggtggag taaaaacatc tgaattagat gctgtagtag gtagaggagg
     5221 acttcttaaa cctataaaag gtggtactta ttcagtaagt gctgctatga ttgaagattt
     5281 aaaagtggga gttttaggag aacacgcttc aaatctaggt ggaataatag caaaacaaat
     5341 aggtgaagaa gtaaatgttc cttcatacat agtagaccct gttgttgtag atgaattaga
     5401 agatgttgct agaatttctg gtatgcctga aataagtaga gcaagtgtag tacatgcttt
     5461 aaatcaaaag gcaatagcaa gaagatatgc tagagaaata aacaagaaat atgaagatat
     5521 aaatcttata gttgcacaca tgggtggagg agtttctgtt ggagctcata aaaatggtaa
     5581 aatagtagat gttgcaaacg cattagatgg agaaggacct ttctctccag aaagaagtgg
     5641 tggactacca gtaggtgcat tagtaaaaat gtgctttagt ggaaaatata ctcaagatga
     5701 aattaaaaag aaaataaaag gtaatggcgg attagttgca tacttaaaca ctaatgatgc
     5761 tagagaagtt gaagaaagaa ttgaagctgg cgatgaaaaa gctaaattag tatatgaagc
     5821 tatggcatat caaatctcta aagaaatagg agctagtgct gcagttctta agggagatgt
     5881 aaaagcaata ttattaactg gtggaatcgc atattcaaaa atgtttacag aaatgattgc
     5941 agatagagtt aaatttatag cagatgtaaa agtttatcca ggtgaagatg aaatgattgc
     6001 attagctcaa ggtggactta gagttttaac tggtgaagaa gaggctcaag tttatgataa
     6061 ctaatgataa aagaataaga atcataactg gtcactatgg aagtggtaaa agtgaatttg
     6121 cgatgaacta tgttgttaag ttaagagata tggtttctgg caaagttgct atagccgatt
     6181 tagatgtggt aaatgtatac tttagaacta gagaaaagaa agagttaatg aaatccttag
     6241 gtatacaacc aatagatagc tcaattaatg ctccaacatt agatttacca gcagtatcag
     6301 cagaggtaat gtctcctatg gtagaccatt catacaattc tgttatagat ttaggtggag
     6361 ataatgtagg tgctagggtt ataggaagat ttagtcattt gttaaaagaa ggcgattatg
     6421 atatgctttt tgtaataaat gcaaataggg agaaaactca aacttctgaa gaagttatcc
     6481 aatatataaa agaaatagaa aaatcttcta aattaaaggt aacaggtcta attaataata
     6541 ctcatcttat taggtttact actattgatg atgttttaag gggtcagaaa gttgcaaaag
     6601 aagtttctga aaaatgtaat ataccgataa gatatgttgc atgtttagaa aatcttgttg
     6661 aacagttacc aaaagattta gaaggagaaa tttttcctat aaaattatat atgagagaag
     6721 actggatgta gtttgagctc aaatatatag aaagtttaag gaggcttagg taaatggcta
     6781 aaggaaaagt atcttttaat caagaacgtt gtaaaggttg tggattatgt gttgaagcat
     6841 gtccagtaaa aatcatacaa ttagactcaa atgtaataaa caaaaaaggg tataacccag
     6901 caactgtttt tgaaatggaa aaatgcatag gatgtgcaag ttgtgcaact atgtgtccag
     6961 atgtagttat aacagtagaa agagattaat ttaattaata tttaaggggg aattttaatg
     7021 gctaagatac ttatgaaagg taacgaagca tttggaaaag cagctataga agctggttgc
     7081 aaatatttct tcggttaccc aataactcca caaagtgaat taccagaata tttatcaaga
     7141 gagttaccta aaataggtgg agcgttcgtt caagctgaat cagaagtttc tgcgataaac
     7201 atggtttatg gtggagcagg tgcaggagca agagttatga cttcttcatc ttcaccagga
     7261 gttgctttaa agcaagaagg tataacatat gcagtaggag cagaagttcc ttgtgttgta
     7321 cttaatgtaa tgagaggtgg tccaggactt ggaagtatac aaccttcaca agctgactac
     7381 tttatgtcta caagaggtgg aggaaatgga gactacagaa ctccagtatt cgcaccagct
     7441 acagttcaag aagctgttga tatgataatg gaagcttttg acgttgcaga ttattacaga
     7501 tcaccagtta tggtagttgc agatggtatg ataggtcaaa tgatggagcc agttgaattt
     7561 agagctcctg agaagaaaag agaattgcct cctaaagatt gggcaactgt tggaactaaa
     7621 ggaaaaagaa aacctaatgt aataaactct ctatacttag agccagaagt actagaagac
     7681 cattgttggc atttacaaga aaaatttgat gcaatggaaa agaatgaagt acaatacgaa
     7741 atgtacaaaa cagaagatgc tgaatttgta tttgcagctt atggaactac ttcaagagta
     7801 gtaaaaagcg caattgatat attaagagaa gaaggaataa aagcaggtct tataagacct
     7861 aaagtattat ggccattccc attcgaagca ttcaaccaaa ttcctaatgc tagaaacata
     7921 ttgactgttg aaatgagtat gggacaaatg gtggaagatg ttaaaatggc agtagaaggt
     7981 aaattaccag tttacttcca tggaagacca ggaggaatga ctccaacacc agcagaaata
     8041 gttgaaaaag ctaaaaaaat tattgccgga gaattggttg caggaggtgc tagataatgg
     8101 ctgttgtatt taagaaaact gaaggattac aagatactca aactcactac tgtccaggat
     8161 gtacacatgg tataatccat agattagttg gtgaagtatt agaagaacta ggagtattag
     8221 gtgatgctgt aggtgttgtt ccagttggat gttcagtttt aggatataaa tattttaact
     8281 gtgacactca agaagctgct catggtagag cgccagctgc tgctacagga ataaaaagag
     8341 ttcatcctga aaatacagta ttcacttatc aaggtgatgg agacttagct tcaattggta
     8401 ctgctgaaat agttcatgca gctgctagag gagaaaaaat aactactata tttgtaaaca
     8461 atacaactta tggtatgact ggtggacaaa tggctccaac tacattagtt ggacaaagag
     8521 ctactactgc tcaatcagga agaaatgctg aaactcaagg ttatccaata agagtaagtg
     8581 aaatgttagc tacattaaca ggagctgtat ttgtagaaag agtagcagtt gatactccag
     8641 ctcatgttag acaagctaaa aaagctataa agaaagcatt ccaagttcaa caagcaggat
     8701 taggatttgg aatagtagaa gtattatcta cttgtcctac aaactgggga ctagctccaa
     8761 atgatgcttt acaatggtta agagacaaca tgataccata ctatccatta ggaaatttca
     8821 aaaatgttga agttgaggag gtgaagtaaa tgtctacagc tagagtaata tgtgcaggct
     8881 tcggaggcca aggtgttatg tctatgggac aattacttac ttatgcagga atgctagaag
     8941 gaaaagaagt ttcttggtta ccatcttatg gaccagaaat gcgtggaggt acagcaaact
     9001 gtgcagtaac tgtatctaat gagccagttg gttctccact tataacagat gatgcaactg
     9061 cagctatatt attaaatata ccagcatttg aaaaattcaa agatgatgtt attcctggtg
     9121 gaaaaataat agtaaatagt tctttaataa aagaaaaagt tgatagaaca gatgtagatg
     9181 tttattatat accagcaaat gaattagcag ctgaattagg aaatgataaa gttgctaata
     9241 tgataatgtt aggcgcttac ttaaaagtat ctgatactgt agatatagaa tctgtactag
     9301 aagcattcaa aaaagttttc ggacctagaa aagaaaaatt cgttccatta aacagagaag
     9361 ctttacaaaa aggtatggat gctacatgtt ctaaagcaac taactaataa agaaaaagat
     9421 gtcaaaaaaa agacaataga attatttcta ttgtcttttt tgctgataag tattaaaata
     9481 tttttatgac tgaaattaag cctataatga tattttatga actataaaaa tataatacaa
     9541 attacaagct tttcaattat gaaaggagaa tctttagtga gaaagtattt tggaacagat
     9601 ggagttagag gagtagcaaa tacagaacta acatgtgatt tagcatataa acttggtaga
     9661 gctggtggat ttgtcttagc tcaaggagac cacagagtaa aagtagtagt aggtaaggat
     9721 actaggatat caggtgatat gttggaagca tctttaatag caggacttat gtctgttgga
     9781 tgtgatgtta ttactgttgg aataatacca acacctgcag tggcatattt aactagaaaa
     9841 tatggtgctg attgtggtgt ggttatatct gcatctcaca atcctgttga atataatgga
     9901 atcaaattct ttaataagaa tggatataaa ttagatgatg aaattgaatt gaaaatagaa
     9961 gaatatatag acgatataga caaaattgat tgttttccaa ttggtgaaaa tgtaggaaga
    10021 aaattacatg aacattgtgc acaaagagac tatgtagact acctaaaatc aataataagc
    10081 actgacttta agggattaaa agtagttttg gactgtgcta atggtgcgtc atataaagtg
    10141 gcaccaatag tgtttgatga actaggagca agtgtaattt caataaatag ttcaccagat
    10201 ggaaataata taaactataa atgtggctct acacatccag aacaacttca aagggctgtt
    10261 ttggaacata atgctgactt aggtcttgca tatgatggag atgctgatag attaattgca
    10321 gtaaatgaaa agggtcaaat tgttgatgga gaccatataa tgatattgag tgccttaaat
    10381 ttaaagaaaa ataataaatt ggcacaagat actttggtag ttacagttat gagtaatata
    10441 gggttgacaa tagctgctaa ggaaaatgga ataaatttat ctactacagc agttggagac
    10501 agatatgttt tagaagatat ggttaaaaat ggatataatc ttggtggaga gcaatctgga
    10561 catatgatat ttttagatta caacactact ggagatggag tgcttagttc tctaatactt
    10621 gcaaatataa tcttgcaaga aaagaaacct ttatcagaaa ttgcatcaat aatgagccaa
    10681 tacccacaag tattagtaaa tgcaacaata aaaaatgaaa ataagaacaa atatatggaa
    10741 tatccagaaa taaaaactga gatagaaaga atagaatcta ttttagacgg aaatggtaga
    10801 gttttgataa gaccatcagg aactgagcca ttagttagag ttatgttaga gggtaaagag
    10861 gaaggtcaaa taaaagaatt agcaacaaac ttagctaatc ttatacaaga aaaattatcg
    10921 taatttaaag ggtattctca gatacaaata ctgaggacac ctttctaagc gccagaactt
    10981 agttatagac ataattattg agtaatatag gaactaagtt gacgaggtca gagttaatcg
    11041 aattgtcggc ggatgctctg cggtgtgttt accatcgaaa gacttcttta aataatagga
    11101 gcaatcctat ggacaaaggg aagccaaagt aaacttatat gacctaactc ttaaaatata
    11161 taaataatat ttttaggagg acacaaataa tgtgtggaat agttggatat ttaggaagta
    11221 gaaaggcagc agaagttata gtagaagggc tttctaagct agagtacaga ggttatgact
    11281 cagcaggagt agcagttaat agttctaatg aagaagaact taatattaga aagtttaaag
    11341 gtagactttc tgtacttgca gaagacttag aaaagaatcc tattgatgga aatttaggta
    11401 tagggcatac gagatgggca actcatggag aaccatctga tgtaaactca catcctcatt
    11461 ttaatcaagc caaaacaata gcagttgttc ataatgggat aatagaaaac tatatggaaa
    11521 taaaagaaga attaatttct gaaggtgtta agtttgaatc tcaaacagat acagaggtaa
    11581 tagcacattt agtagataaa tactatgagg gtaatttatt agatgctgta tacaaaacta
    11641 tatcaaaatt aagaggagct tatgcattag gtgttatatg taaagaacat ggaaatgaat
    11701 tagttgcagt aagaaaagat agtcctcttg tagttggtgt tggtgaaggt gaaaacttta
    11761 tagcatcaga tatacctgca ttattaaaat atactagaga tgtttatttc ttagaaaatg
    11821 gagaagtagt tcatctaaaa gacgaaaatg taacagttta tgactctaat agaaatcttg
    11881 ttgaaaaaga agtatttcat gtaacttggg atgtagaagc tgcgtctaaa ggtggatatg
    11941 actactttat gtcaaaagaa attcatgagc aaccaacagg agttagagaa actttagaaa
    12001 gaagacttga tgataatgga aatataattc tagacagtat aaatatttct aaagaagact
    12061 tagaaaaaat aaataaagtt tatatagtgg cttgtggaac agcatataat gctggattac
    12121 ttggtaagta tgccatagaa aaatttgtaa atataccagt aataactgat atagcatcag
    12181 aatttagata tagcgaccca tttgtagatg aaaattcatt agtaatatta gttagccaat
    12241 ctggtgagac agcagatact ctagcagtat taagagattc aaaggctaaa ggagcaagaa
    12301 tactttcaat aactaacgtt gtaggttcat ctatagcaag agaatcagat gatgtattct
    12361 atacttgggc aggacctgaa gtagcagttg catcaactaa ggcatatact actcaaataa
    12421 cttctttata catgatagct ttagactttg ctatcaaaaa aggaacaata actagagaat
    12481 tttatgatag tatgatttct aagatgaaag aaataccatc aaaaatacaa gaaatactag
    12541 acaatgaaga atatataaaa gaagttgcta aaacagttgt tagttctgaa catgcattct
    12601 atttaggaag aggtatagac tatagcttag caatggaagg ttcattgaaa ttaaaagaga
    12661 tttcatatat acatgcagaa gcttttgcag caggagagct aaagcatgga acaatagctt
    12721 taatagaaaa aggaactcct gtaattgcca tagctactca agaaaagtta tttgaaaaaa
    12781 tggtttctaa tatggaagaa gtaagagcaa gaggagctta tgtagtagca atagctcaaa
    12841 gccataataa ggatgttgag aaagctgctg ataaaataat ctatatacca aattcagatg
    12901 atattttatc accaatatta gcagttgtac caatgcaatt acttgcttat catgtctctg
    12961 tactaagagg atgcgatgta gataagccaa gaaatctagc taaatcagta acagttgaat
    13021 aaaaacagat taaaaattaa atagataata tttattgaaa agaactcatc ctgttatttg
    13081 tattttatag gatgagtttt ttagataaat attaaatttg ttttgttttt gctataataa
    13141 attttataaa aagattgata ttaaatcatc tgtaaaatga taaatatata gaccatacca
    13201 ggtataggga acgataaata tagttcatat aaaatatagt gagtacttaa taaacatata
    13261 gtcaatatca gacataaaaa ataatagctt atgagaaaaa ttaaaataca aggtattagt
    13321 aaccttgtga taagataaag tgagtagttt aaaataagaa tataaggaac tatttataaa
    13381 agaatataat gaagctaata gagtataaga aaattacttt attttagtaa aataatttca
    13441 aataaaaatt tttttaaatt gggagtataa attatgacaa atgattttaa aaaagaaaag
    13501 aaagaagatt attttgttaa tcttaaggca atatctactg aagttttaca agaaaaagtg
    13561 caagataacg cttgggttat agttgatact cgcttaaatg atgcttataa tggctggaag
    13621 ttagatggag taaaaagagg tggacatata aaaggagcag tagatttttc tgctaattgg
    13681 ttaagtgtat actcagatag aaaagatgaa gtgttagaac aagcattgaa aactaaaaga
    13741 attgatttag ataaaaatat agtattgtat gatgcaaatg gaaaagatgc tttggttgta
    13801 gcagattatt tatctaaaaa aggatataaa tatctatata aatatgatat taaacaatgg
    13861 gcagacgacg aaaatcttcc aatggaaaga tataaaaatt atcaaatgat agttcctgct
    13921 tttataataa aagatatatt agatggaaaa attcctgaga catttgaaga ttcaaagaat
    13981 ataaaaatga ttgaagcgag ttggggagaa gaatcgtata caaaagggca tatacctaca
    14041 agtgttcatg taaatactga tattatagaa cctcctccaa catggatgct tgataatgat
    14101 gataacttaa ctaagtttgc tttagactat ggattaacaa aggatgatac tgtaatagtt
    14161 tcaagtagta cacctatggc atcttataga ctagctgtta tattgagata tataggagta
    14221 aaagatgtaa gagttttgaa tggtggaaca aactcatggt tatcagcagg atatgaatta
    14281 gaatttatta gtaatccaaa acattcatgt actaattttg gagcagatat accagttaac
    14341 tcacaattaa ttgttactac atctgaatta agacaaaaac taaaagaaaa aaataagttt
    14401 atactagtag ataaccgtac ttgggatgaa catataggaa aagtatctgg atatacatat
    14461 tatgataaaa aagggcgtat accaggagct ttatatggac attcaggtag tgatagtgtt
    14521 tcactagaag aatatcgtaa tattgataat acaatgagaa ataaatatga gattttagaa
    14581 atgtgggaca aggaaaatat agatgtgaat aaacagctta tatttatgtg tggaagtgga
    14641 tggcgtgctg ctgaagtatt aacatatgca aatgtcatag gagtggaaaa tacctccctt
    14701 tatagtgatg gatggatggg ctggagtctt gataattcaa atttaattga agtgggagaa
    14761 cacaaataaa gtttttgaaa gtgcaataga gttgtttaaa acaaaggtgt ttttgattta
    14821 ttaggaagag tgtgtaaatt gtgtattggg aagtgtactt aggtatgttc atttggagct
    14881 atggaaattg ataaaaaagt attatctgtt tattttgttg gtaaaatatg aatagattat
    14941 agattataga ttatagattt aagtatagat taagtaattt atattacaga agagaatata
    15001 taagaattaa tgcaagatgt atttgataca tataagaaat tggcaagtcc aggagaagga
    15061 tagagaaaat tgagattgaa gagtttgaaa gagattatta gatgaaaaat acaaaaatgt
    15121 ataaaaatac atattgagaa agtatatctc tcttaaattt gttaataatt ctattataca
    15181 gaaaaacata tttaaggggg attttttact atgaaaaaag taaaattagc tataagcttt
    15241 tttatattaa tgattatagg aatgacaata tcttatgcag atacaagtat aaatactaga
    15301 tacaatagat taagtaaagc tcttgaaata tcagaagcaa attttaaatt ttataatgtt
    15361 aaaattaatt ctgttataaa tcataattta tcaaataaag aatttcataa tatttttata
    15421 gaaataatta acaatctaaa gttggataaa aaaggaataa attggaatca aaaagggtct
    15481 ggcgataaaa tacaattatg tgctactata aaaggtagcg ataaagaaat ttctataaaa
    15541 ggaataaata aaaataacaa agaaagttac atagtagttg acatattgga taacaaagta
    15601 tataaacata aagaggttat ttatagtaac gtagaaaatg tgttaaataa atattcatct
    15661 caagtagatg tgtctgcttg tattgttgga gaatacacaa aaaggttaca aaacaacaaa
    15721 tatgatgata ttttacaaaa aatattatat aatatgagtg ctaagcaaat agatgaagtt
    15781 aaagacgtaa actttttatc tataacagca tatagtaaag tattaaatga ttatgaatta
    15841 gaatatttag gggaaaaaat taatttaaat ataggaatta aatataatga ggatgacgga
    15901 aaaacactca tatatattgc cacaccaatt ataaaattag attattaatt atgaggagat
    15961 caaaaaatat ggctaagata atagtaaaaa agagtaatcc acttaaaggt agtgttaaaa
    16021 tagatggtgc aaaaaatgca gttttaccaa taatagcagc gactttatta gcaaacggaa
    16081 aatcaacatt aaatggagta ccaaatttaa gagatgttca tgttatatca gatttattaa
    16141 gacatgtagg agcagaagtt gaatataaag aaaatacact tactgttgat gcaagcaata
    16201 taaaaacttg tgaagctcca tatgagcttg taagaaagat gagagcttct tttttggtta
    16261 tgggaccatt gcttgctaga tttaatagta cgaaaatttc tatgccagga ggatgtgcta
    16321 taggaacaag acctatagat ttacatttaa aaggatttaa agctttaggt gcaaagatag
    16381 aaatggacca tggttttgtt gaagcagcaa cagaaaagtt agtaggaaat aaattatatt
    16441 tagatttccc atctgttgga gcaactgaaa acataatgat ggcagcttct ttagcagaag
    16501 ggactacaat aatagagaat gcagcagaag agccagaaat agtagattta gcaaacttct
    16561 tgaacgaaat gggagcagat gttaaaggtg caggtactaa tactataaaa ataaaaggtg
    16621 ttaaagagtt aaaaggagca gaacataatg taattccaga cagaatagaa gcagcaactt
    16681 atatggttgc agcagctatg acaaaaggtg atataactgt tgaaaatgtt ttaatggagc
    16741 atttaaaacc agttgtagct aaattaagag aagctggttg tgaaataaca gaaatggaca
    16801 attctgtaag agttgtaggt ccaaaagtat taaaaccaat agatataaaa actttaccac
    16861 atccaggatt tcctacagat gttcaagcac aatttatggc tatgcttact gtagccaatg
    16921 gaactggtgt agttatagaa actgtttttg aaaacagatt tatgcatgtt gctgaattta
    16981 atagaatggg tgctaatata aaaatagatg gaagaagtgc ggttgttaat ggtgtagatg
    17041 agctacacgg tgcagcagta aacgctactg atttaagagc aggggcagca cttattttat
    17101 gcggtcttat agcagaagga gaaactcaaa taggagaaat ataccatatc caaagaggtt
    17161 atgttgatat agataagaag ataacagcac taggtggtca aatcgaaata gtagaagatt
    17221 aataattggt ttatagaaga aagttataaa ttaatagggt tgttcatata cttaaataca
    17281 aggttttaaa agctaaggag gagagtatat gaagaaccca ttggttgttt tgttaggatt
    17341 tgtgacttgc tctgtgttag ttccatcact tataacttta gtttcttata aaaatgtaga
    17401 attaactgaa aaaccagaga gcccagtatc tataaacaaa actattaaaa aaagtgatat
    17461 tgaagacaaa ggtaataaag aagaaaaaaa tacagtgaac tatgaaactg taaataaaaa
    17521 agcaccaatt atcaatgtat ataatcatat aacagggaaa accgaaaaga tggacatgga
    17581 gaactattta tgtggagtac tagctggtga gatgtcttca gagtttgata tagaagcttt
    17641 aaaagctcaa tctgtagcag ctagaacata tgtagtatat aaacaggaac atggtaaatc
    17701 tagtaaacat aaaaatgcag tagtatgtac tgattataaa cattgtcaag aatataagag
    17761 ttatgatact cttaaaaaat taaatggtga agaatggatt aagaataaat attccaaaat
    17821 ccaagaagca gttagaggaa ctaaaggtca aataataact tataatgata aggcgatact
    17881 tcctctttat ttttctacat cttcaggaaa aacagaaaat agtgaagaag tattttctgc
    17941 aaaatatcct tatttaaagt ctgtggaaag tccttatgat aagtattccc ctaaatttgc
    18001 gtcaacactt aaaataagta acacagattt tgttaaaagt cttagaaggg catatagcac
    18061 tattgtgata gatgtgaata atttaagtaa acaagtttca ataactaaaa gaagtgatgc
    18121 cggaactgta gaaaaaataa aattaggaaa taaagaattg actggaaaag acattagaac
    18181 tgtttttaaa ttgaactctg caaactttga cataaaattt ggagaaggat acatagattt
    18241 cgtggtaaaa ggatatggtc atggtgttgg tatgagccag tggggagcag aaggaatggc
    18301 agaagagggc tataaatatt atgatatatt atcacattac tacacagata caaaaataaa
    18361 agatatatac taataattgt ataaaatgcc aaaaacacgt caataatcca aatgtagaaa
    18421 tatatttgga ggtgcaaaat gaagaaaaag ctgttagaaa aagatggttt ttatttatct
    18481 ttgtttgtat gtgtttgttt attagcagta ggtggagttt ggtttacaaa taataatgta
    18541 gataaattgg cttctaataa aggaattatg gaaaatgcta ataaagatag tgaagaggaa
    18601 atacatttaa ttgaaaaaga caagaaagat gctatcccta ctgcaacgga ttcaaaacaa
    18661 aacttagaaa aagctaagtc aaaagaggaa aataaatcga gtacaacaaa attaaattac
    18721 attggagata aagtaataag aggatattca gaaaaagagc ctagttattc taaaacactt
    18781 gatgtttggg aaactcataa aggtgtagat attagttgta ctaaaggcaa agaagtaaaa
    18841 tctctattaa acggaatagt agtagatgta tttgatgatg aagaatatgg acaatcagtc
    18901 aaaataaaaa gtgacaataa cattgtagta gtatattcaa atctagataa aaatgttagt
    18961 gttaagaaag aacagaaggt aacagaagga caatctctag gtactgtagg tagtacttct
    19021 caaatagaaa gtgaagaagg tatacatgtg catttagagg cgtatagtgg agaaaaatct
    19081 atagacccaa tgagtctaat taagtaatag tataacaagt ttaatcatat ttggttaagc
    19141 ttgttatatt ttttggtgtt tttacatata tatcattaaa gctattatgt gaggggggta
    19201 atctttgaga tctcatatag aggaaagggc catagtggta gcaaaatata tacttgaaaa
    19261 aaacactaca gtaagacaaa ccgccaagac atttggagta agtaaaagta caattcataa
    19321 ggatgttaca gaaagattga aggaaataaa tccatccctt gccaaagaag ttaaaaatgt
    19381 gctggacaaa aataaatcag agagacatat tagaggggga ttagcaacga aattaaaata
    19441 tgagaaggaa cataaaaaaa tgtaggttaa aaacctactt tttttattga attaaattat
    19501 aaaaagaaat atattaagta attataaata gcaaaataat aatactctca aaagatttat
    19561 tttctcttga ttaaagcgag atttttgtat atgctttatt ataggagtat taaaataggc
    19621 ttataatata atctaatatt ataaataaag gagttgaaaa aatggctgga gctgatatag
    19681 gcatagattt aggtactgca aatgtgcttg tttatgttag tggtaaggga atcgttttag
    19741 aagaaccatc tgttgtggcg atagacaaaa gaacagattc tgttttagct gtgggagaag
    19801 aagctaaaaa gatgataggg agaacaccag gtaatatagt cgctataaga cctttaagag
    19861 atggtgtaat ttcagattat gatgtaactg agaagatgtt aaaatctttt atagataaga
    19921 tagttgataa aaagggattt ggaagatttt ttatgccaag aattatggta tgcgtaccaa
    19981 caggtgtcac agaagtggaa aaaagagcag tagaagatgc tacgagacaa gctggagcta
    20041 gagaagtata tatcatagaa gaaccaatag cagctgccat aggagctggt gtagacatat
    20101 cacagcctaa tggtaatatg attatagata ttggtggagg tactgtagat atagctgtaa
    20161 tatctctagg aggagctgtt gtaagtgaat ctataaaggt tggtggagat agatttgatg
    20221 atgctatagt taaatatatg aaaaaacaac acaatcttct tataggagaa agaacagcag
    20281 agaaaatcaa gtttgaaata ggttctgcat ttaagagaga agaagaaaaa tatatgaaga
    20341 taacaggaag aaatttaatt acaggacttc ctagttctat aactataaat tcaacagaaa
    20401 tgttggaagc acttagagaa tgtgttgagc aaatagtagt tgctactcat gctgttttgg
    20461 aaaaaacgcc tcctgagtta gcagcagata taggagatgt cggtataata atgactggag
    20521 gaggttcatt attatatgga ttagataaaa taatagaaca gaggacagga ataactgtta
    20581 caatagcaga tgaaccatta tcttgtgttg caaaaggtac aggaatagct ttaggttcaa
    20641 tagacttact tgaaactggt gggtctttca aaagaaaata attaggagag tttagaatgt
    20701 taaatataga tgaaataaaa aaattaatac cacatagata tccattttta ttagtagaca
    20761 agattacaga gctagaagtt gggaaaagag ctgttggtat aaagaatgta acagttaatg
    20821 aaccattttt ccaaggtcac tttccagaat atcctttgat gccaggagta ttaatagtag
    20881 aagccctagc acaagtatgt ggagtggcaa tgatgtctgt agaggaaaac aaaggaaaac
    20941 taggtgtatt tgcaggtata gataaagtta gaatcaagag agaagtaaga ccaggagata
    21001 cattaactat ggaagttgaa atgacaactc ttagaaaaaa tatagctaag gcagatgcta
    21061 aggcatatgt aggtgaagaa cttgtctgta aaggggaatt aatgtttgct ttagtagaaa
    21121 aataaaaact tgaaatataa aagtaaaaag gtagataatt tggagtattt aatcagatac
    21181 tctaaaatat ctaccttttt atataaagaa ttttatcatt tagtttatat ttagattagg
    21241 tggatactaa taaagccaag gctattgttt cagctaaatc taatataaag ctaaggcgta
    21301 tattattaaa tgaaagttta ttattttcat caattttatc tacaattcct actatagaat
    21361 aatttcctat ttgaggtagt tttttaccaa caccttttcc gggcaggata ggtccttctc
    21421 taatctgtat attacctatg ttactctgcg accccaagca agcatctata gccaagaagt
    21481 taccttgtat atgtgtattt tttatagtat ctaaagactc atatatattt aaggcgtgaa
    21541 tagggttatc tagtgtaccg taaacggggt atttaaagtt actgttctta agtattgttc
    21601 caactaaagg gcctaaagta tcacctatag ccctgtctgt tcctatgcaa acaacaatcg
    21661 tattttcatt aattatagtt tttagaactg aacttagcat ctgtataaca tcatcatcgc
    21721 tgtagtttac tttagctaaa tacaatagga acaccccctt caaaaaaata tatgaataaa
    21781 aagcattaaa aagacctaac tttaaatttc agatagatag aaaattttat ttgtcttaca
    21841 aaaaaaggaa tagaaaaaat atgactaaaa atattgacaa aattttaaaa aaatagtaag
    21901 ctagtaaagt aaaacaaaac ttaaatcttg attaccttat caagagaggc tgagggatag
    21961 gccctgtgaa gcccagcaac cacccaaatg ggaaaaggtg ctaattccta caagacaaaa
    22021 gtcttgaaag atgaggtcag ttaattagta tgtaattacg attattaacc tcttcttata
    22081 aaggagaggt ttttttattt tgagtaaatt tctaaaatta aaaataaggt aaaacctata
    22141 ataaaaatta agaataaata agggggaata aaaatggcaa gacatttatt tacgtcagaa
    22201 tcagttacag aaggacatcc tgataagata tgtgaccaaa tatcagattc aatattagat
    22261 gcattattag aaaaagaccc acaatctaga gtagcttgtg aaactacagt tactactggt
    22321 ttagttttag tagcaggaga aataagtaca tctgcttatg tagacattcc taaattagta
    22381 agagaaacag taagagaaat tggatataca agagcaaaat atggatttga ttgtgatact
    22441 tgcgcagtta taacttctat tgatgaacaa tctggagata tagctatggg agttgatgaa
    22501 ggcctagaaa gtaagactgg agaagagata gaagaagaaa tagaaaaagt tggagctgga
    22561 gaccaaggta taatgtttgg atttgcatgt aatgagactc cagaattaat gccacttccg
    22621 atatctttgg cacataaatt atcaagaaga cttacagaag ttagaaaaac aggtttagtt
    22681 gattatttaa gaccagatgg aaaaactcaa gttactgttg aatatgaagg aagtaaagct
    22741 gtaagagtac atacagttct tatatcagct caacattgtg aaacagtatc aaatgataaa
    22801 ataagagaag atttaattaa tcatgttatt aaggaagtta taccagcaga attacttgat
    22861 gaagagacta aaatttatat aaatccaaca ggaagattcg ttataggagg accacaagga
    22921 gatacaggtc ttacaggaag aaaaataata atagatactt atggtggata ttctagacat
    22981 ggtggaggag ctttctcagg aaaagaccct acaaaagttg atagatctgc tgcttatgca
    23041 gctagatatg ttgcaaaaaa tattgttgcg gctggtcttg cagacaaatg tgagatagaa
    23101 cttgcatatg ctataggtat agctagacca ttatctatat ttatagatac ttttgggaca
    23161 ggcaaggttt cagaagaaaa acttgttgaa ttagtaaata aacactttga tttaagaccg
    23221 ggagcgataa taagagactt agatttaaga aagcctcttt ataaaaaggt tgctgcttat
    23281 ggtcactttg gtagaactga tatagattta ccttgggaaa gaactgacaa ggttgagcag
    23341 ttaagaaaag atgctttagg tgaataattt ttaactaaaa agctgttaga atgtaatttt
    23401 atgattactt tctaacagct tttttattat gagttaaata tttttaataa atgttaattt
    23461 atcatcatat aatgaataaa cagtatttaa tctggtcaat acattttata taatactcta
    23521 ctaaatttat acatattatg ggatatatgt taaaggatgg ttaagaatgt gttaactaat
    23581 gttaaataat taaaaatata ttgaaatatc acaataatga gtctaatata atcttaataa
    23641 acttacactt taaaaataat tttaattggg ggggagtagt gtatgtcagg caaagtaaat
    23701 attaaaacgg ttataagttt tgctggagct tatgttgcta ctgtaatagg ttctggattt
    23761 gcaactggtc aagaaatact gcaatttttt acgttttatg gatatgcggg tattataggt
    23821 ggaataatct ctatggtact attttcatgg tttggagcag aagttataga taagggaaga
    23881 gaattgaaac ttaaggagcc aataaaaatt tatcaagtat attgtggaaa atatcttgga
    23941 acattttttg aatggtttgg tccattgttt ttatttggaa cattagtaat aatgattgca
    24001 ggagcaggag ctacattatc agagtactat ggattaaatc catatgtagg taggattggt
    24061 atggcaatcg tttccctaat aactgtttca ttaggtttga caaggctttc taaaatacta
    24121 ggtaatatag gacctataat aataatattt acacttttag taggagcaat tagtttattt
    24181 agcaatattg atgctttatc aaatgctgga aatatggttg atagtttaaa tattaaaact
    24241 gctacatcaa atggatattt ctcgggagta ctttatactt gttacaatgt aataatagta
    24301 ataacattct tgacaggaat gggagcttct gcagtaaata agaaagatgc tgtatggggt
    24361 ggtatagtag gtggagtagc acttatggca gcagctataa tgatgaattt ggcattactt
    24421 tcagacatag gaaatatata cacaaaagag ataccagcac tttacttagc tgataagata
    24481 tctccaataa taggtatttt attctcagta gtacttttac taggaatata cactacagct
    24541 gtaccattgt tatggtcagt aacaaaccga tttgtagaag atgaccaccc taagtttaaa
    24601 attataacaa tagtggtaag tatattagct tgtataggag gtttactgcc atttgataag
    24661 ttagtaggta cactatatcc atatacaggt tacatgggaa ttttaatttt actatgtatg
    24721 ctttatagaa gaattactaa aactgagggg tacaaggaga ataaatctga aataagttag
    24781 tactgtaata tacttatgga atttaattta tactctaaat atagagcaat taaaataaaa
    24841 tagctattta aatatggtac ctgtatttca tggtaccata ttttatggat gcagattttt
    24901 tttgtttctg ataaaatgta taatagttgg aaattacgtt aagtataaaa atataaaact
    24961 tttctacgat tatcatagtt ttaatatata aaattatact aacatttaaa tggagcgatt
    25021 attagtattt ttaggagata aaaatggaaa aattagaagg aatgataagt gaaatagtct
    25081 ttaaaaacga agataatggt tatacaatag ctcacctggt aaatgaaaat gatgaaattg
    25141 tggttgtagg atgtatgcct actttggcaa ttggagaaag catagaagtt gaaggaaagt
    25201 gggtaaatca taagatttat gggactcaat ttgaagtgaa tagttttatg ccagtaacac
    25261 catcatcctt agaaggaatt tatgtttact tatcttctgg aatgatacat ggtattggtg
    25321 aaaaaatggc aaaaagaata attgataagt ttggtgtaga tacgttagag gtgatacaaa
    25381 attcaccaga aaaactacaa gaagtagaag gcatagggag taaaaaagta aaacaaatag
    25441 taaaaagtta tgaagaagac agagaattga gaaatataat aatacagcta tctccttttg
    25501 gaataacacc aaattactgc ctaaaaatat ataaaaaata taaaagcagt gcaatagaag
    25561 ttataaataa aaacccatac caacttgctg aagatataag aggaattgga tttaaagtag
    25621 ctgatagtat agcaagtaaa attggtatag ataaaaactc taaagataga atttgtcagg
    25681 gaatcttata cactttaaat aaatctttaa gtaatgggca tacatattta ccagagcatg
    25741 ttctaataca agattcggaa aaattattgg agctaaatgg agaaataata aaagagtgtg
    25801 taatgatgct agtttataat caaaaaatac atatagagaa agtaaacaat gaaaatctta
    25861 tataccttat gccatactat ttagctgaaa atggagtatg tagtcaaata gtaaaattat
    25921 cacagtatga atttgaagac ttaaaaatag atatagataa tgagattaat gttttagaag
    25981 aagataagaa aattaagtta gcagaaaaac aaattttagc agtcaaagaa tctgttaata
    26041 gtggagtatt aattataact ggtggaccag gaactggtaa aacaactacc attaatgcta
    26101 tcatagatat atttgaaaat aatggtaaaa gtgtgacttt ggcagctcca acgggaagag
    26161 cagcaaagag aatgagtgaa acttctaata aagaagcaaa aactatacat aggttgctag
    26221 aaatgggatt ttcaacagat gatgatttaa ctttttttaa ggatgaagaa gacccaataa
    26281 attcagatgt aataattgtt gatgaggtat caatggtaga cattatctta atgtacaatt
    26341 tacttagagc tataaagtta ggaacaagag taattttagt tggagatagt gaccaattac
    26401 cttctgtggg tgctggaaat gtacttaagg atatgattaa ttctaatatt ataaatgtag
    26461 ttaaattaaa tgaaatattt agacaagcgc aagaaagtat gataattgta aatgcccata
    26521 agataaacaa tggagaacca ctttatctaa atacaaaagg taaagatttc ttttttataa
    26581 gaaaatcaac taatgaagaa attttaaatg aaataatagg attggttaat gaaagattac
    26641 ctaaatttta taaagttgat aaattaaaag atatacaagt tttatcttca atgagaaaag
    26701 gtgaattggg agttactaat ctcaatatag agttacagaa gtatcttaac aaaaaagaaa
    26761 aatttaaagt tgaagaaagt ttttctaaaa gattatttag agttggcgat aaggtaatgc
    26821 aagtaaaaaa taattataca aaaaaatggg aaacagaaga ccaaaaagaa agtggagaag
    26881 gtatctataa tggagatata ggatatgttt atcacataga taaagataag aaaactattt
    26941 atatattatt tgaccagact aaaattgtat catacctata tgatgaatta gatgaaattg
    27001 accatagttt ttgtacaaca atacataaaa gccagggaag tgaatttcca gttgtagtat
    27061 tgccaatagc gtgggctcct cctatgttac ttagccgtaa tttattatat acagcagtaa
    27121 caagagcaaa aaaattagtt gtattagttg gagatgtgaa atatcttgaa tatatgataa
    27181 aaaataatag agttaatcaa aggtattcaa atttaggata taagctaaat aaatttaaac
    27241 aagaagggtt gttgatagaa taaatatgaa aatatgcaat gataatttta ttaagaattt
    27301 taaaaatatg attaataaat gtttggattt tatatatcct gagaatataa gttgcataat
    27361 ttgtgataaa tccataaaga aaacaaatac ttattcaata tgtaaaagtt gttttaaaga
    27421 aatgaatttt atacaagatg gttgcatgaa gtgtggaaaa ccaataatac gtcattcaat
    27481 tgaaaaagaa tttattgaag agtgtagtta ttgttttaat aaagactttt attttgataa
    27541 atcaatatct tgtattgaat acaatgatgt gacaaaaaag atggtgttag ggctgaagta
    27601 taaccaaaaa acctttatgg ctaagtatat agctcaaata atgaaagaaa aattatattt
    27661 agaaaacata aaatttgatt atatattatt tgttccactt cataaaaaaa ggctaaataa
    27721 aagaggtttt aatcaggcac aaaaaatagc atttaattta agtaaaatag taaatattcc
    27781 attattagat tgcataagta gaaaaaaata tacaagaatg ctatataaat tgaataagaa
    27841 agaacgaaaa gaagaattaa aaaatgtatt tgttgttaaa gaaaatgtta aattaataaa
    27901 taataaaaat atacttttaa tagatgatat atttactact ggtctaacaa caaacgaaat
    27961 ttctaaactt ttaaagttat caggtgctaa taaggttttt gtattgactc tacttacaaa
    28021 agcgaatgat aattatatta tggaataatc ttatatattg acaattttag tttaaaatat
    28081 taaaatgaat aagtgatatt taggtctgtg gttgaaagtc caagccagtc gcaggcaaag
    28141 ggatccacgt aagttaacac taaaaattgg gttaatgatc atggtgcggc ttagaagtaa
    28201 gacctaccga taataaaatc gagagagagt agtagtgcgg cgaacccaag cgaaccctcc
    28261 agtaggcgag tgtggggtca aaaaccaggt cagctaaata tcatattaaa agagagctag
    28321 cataccttta tgtatagctc ttttttatat ataataaatt taggttgagt cataaagagg
    28381 tgatatgttt gaataaaaga caagaaaatt tattaacaac attgctatta aaagaagagt
    28441 ttataaatgt taataagatt gccaatgatt ttgagtgttc agaaaggaca ataagaaatg
    28501 attgcaaata tattgatgaa tggttatcta ctttttgtaa tgcttatatc aaaagaaaac
    28561 ctaatattgg gattaaattt agtggagatg gaacagacaa aatactggta aatcagaagt
    28621 tgcgaggtga agttaaaaga gtaaatagtg agcttcataa gcaagttgag atattaaatt
    28681 tactactttg taataataaa aaagttactt taaatgattt atctaataag ttgtacataa
    28741 ataaaaatat tgtcagagaa gaaataagta aattatcagt agcattaaat aattataatt
    28801 taaatatctc gactaaaaaa ggcagtggta tatatattga aggggatgag aaagacataa
    28861 gaataatgtt agtatcattc ttatttaaat atatagataa atacagatta aacatagatg
    28921 aaatagagca cttccatata gtagatataa taattgtaaa aaacataatg cttactatag
    28981 aggaggatat ggatataaga cttacagata tatcattcaa gcaattgatg ctatttttgc
    29041 ttataaatat aatacgaata aggctgggaa attctttaaa agtatcaaat actaagaaag
    29101 agcttaagct aaaaatgctt atattggata tagaagatga attgaaatct aatttatcca
    29161 tagtattaaa ttatgaagaa aaattgttta tagaatcttt aatattgggt atgaacaaac
    29221 aaataaataa taataatatt aagaaatctt tatatctaaa tgaagaatta gcaagttata
    29281 caaaaaaaat tataaattta gtatcagaag aatcaggaat aaattttaat aatgatatat
    29341 tactttatga acaattaata tgtcatttga atgttacaat gcatcaaatg aaaagcaatg
    29401 tttacttaga aaatccactt ttagataaca taaaaactaa attttgtttt ttatttacag
    29461 taatatcaag ttcaatagaa attgaattaa aaggaaaaca aataacggaa gatgaaattg
    29521 gttatcttac acttcacttt caaacctctc tagaaagaaa atacagcaaa agggaatcaa
    29581 ataaaaaggc aagtattgta tgtccattta gttttggagt aagtatgcta ttaaaagtaa
    29641 agatagaaaa gagatttgat aacataaaaa ttattgaaac attaagagag gaagatttaa
    29701 aaagagataa ctttaataag actatagatt ttataattgc atttcaagag tatgaaaata
    29761 tccaaaaacc aatttttata acaacaccat tatttactga tgaggatgag aataaactta
    29821 aagagttcac aaacaaaata aaagaaaaag acacttcata taaacttatg aacagattaa
    29881 tgatgtctga ttatttaata agagagttag aacatgatga tatttatgaa gctataacat
    29941 atttaactaa tttattaatt gaaaaacatt atgcagaaaa agagtattta caatctatta
    30001 taacaagaga aaagtcatat ccaaccaatg ttggaaaagg aatattattc cctcatggag
    30061 acatgaaata tataaaacaa tctgttttat gttttgcaag gttaaaaaca ccaataaaaa
    30121 ttagaaatgg aaaggatata aagattatac ttttgttagc atataaaaaa gatgatgata
    30181 gaaaagtatt tagagaatta tttaaagaaa tatctaattt aacagaggat gaaaatatgc
    30241 tagatattct aagtaaatgt gacattgaaa aggtaaaaga tattcttata taaaattcat
    30301 agtgaactat ggataagcac aaaattttcc atgtgatgga aaaagttgtg catgtttttt
    30361 tgtttttata agatattata tgtttgtaag gtataaataa tctaaaagta gagaagcaac
    30421 ttaggaggaa aaaatggaag aaatagtttt aaagattata attcatgctg gaaatgcaaa
    30481 atctatgctt tatgaagcac ttgactatgc aaaggaaaac gattttaaaa aagcagatga
    30541 attaattgaa aatgcaaatg aagaaatttt aaaagcacat aaagtacaaa ctgaacttat
    30601 acaaaaggaa gctgggggag ataaatcaga tatatctatt ttattgattc actctcaaga
    30661 ccatttaatg acttgtatga gtgagagaaa tcttataaaa gaaatgatta tgttaagaaa
    30721 agaaattcaa aaattaaaat aaaaaaatta agggggattt aaaaatgaaa agaaaagtat
    30781 atttattttg tagctttggt atgtcaacaa gtttacttgc agataaaatg cagaaggtag
    30841 cagatgaaca caatttacca atagaagtag aggcatttcc gatagcagaa attgacaaaa
    30901 tagttgaaga aaaaaatcca gattgtatat tattaggacc acaagttaaa tacatgctaa
    30961 aggagttaaa accaaagttt gaagctcaag gaaaacttat agatataatc aatgaagttg
    31021 attatggaac tatgaatggg gaaaaagtat taaaacttgc tataaagcta ataaaatcta
    31081 aacaagcgta gaattatagt aaaaaataat aggaaatgag ggtggataga tgaatagatt
    31141 ggaaagaata cttatgccat tggctgaaaa aataggtaaa aataaattat taattgcaat
    31201 tagagatggt tttttagtat catcaccatt attaataata ggttcattat ttttattagt
    31261 agcaaatttt cctataaaag gatggaatga atttgtaggt caaatttttg gtccagattg
    31321 ggctgtaaaa ttgcaacaac caactgtagc aacatttgaa gtaatgactc tacttgcagt
    31381 tttagggatt ggatattctt atgcaaagca aatagatgta gacccaatag catcagcagc
    31441 agttgcaata gttgcctttt ttataataac accatttgta ataccatata caccagaagg
    31501 aacagaatca gtttacatgg taacaggtat accactaggt tggatgggtt ctaagggaat
    31561 gtttgtaggt atgataacag caataacctc tgtaaaatta tttgctgcag ttgtaaaaaa
    31621 aggatggaca ttgaaaatgc cagatggagt tcctccaact gtatcaaaat catttgcagc
    31681 attaatacca agtgcaatag ttatggtagt tttcttttta gttaagatag cttttgaagc
    31741 tacaccatat ggaagtatac atgaatttat atttaagttt ttacaaatgc cattattaaa
    31801 attaggaaat agtttaggtg ctatggcaat cgcttatata ttcttacatt tattctggtt
    31861 ctttggaata aatggaagta gtgttgttgg ggctgtgtat aatccaatat taaaaattct
    31921 atcagctgaa aacttagctg cttttcaagc tggttcaaaa ataccaaaca taataacagg
    31981 tcaattccaa gatatgtttg cgacatttgg tggagcaggt agtacactat cattagtcat
    32041 agctatgtta ttaatatgta aaagtaaacg tataaagtca atgggaaaac tatcaatttt
    32101 accaggaata tttggtataa atgagccatt gatatttggt ctaccaataa tgcttaaccc
    32161 aatactattg ataccatttg caatagttcc aacaataaat ataataatag cttacttctg
    32221 tatgtcagca ggattagtgc ctcttacaaa tggagttcag ttaccgtgga caactccaat
    32281 tatattctct ggttttttaa caacaggatg gcaaggtgca gtcttacaat tagtacttct
    32341 tatactagga atatttatgt atataccatt tataaaaatg ctagataagc aatacttgag
    32401 agaagaaaat gaaactgttg aagaggaaga tgatgatata tcttttgatg atttagtatt
    32461 ataggaggaa gattatgaag aaaatagtta tgatattgga ccaaatacaa gctggagctg
    32521 gaggaaaaga gaaaagtaat atacctcctg ctggaaaatc aagcccatta ggaccaggtg
    32581 taatgatgga tccattttta aatgaatcta aggtaatagc taccttattt tgtggggatg
    32641 aattttttgt aaataatcaa gaagaagtaa cgagtaagat gatagctatg gtaaaaaaat
    32701 taaaccctga tgtagtaatc tgtggaccaa gctttaatta cgaaaacttt tctaagatgt
    32761 cagcaatact gtctaaaaat ataaatgata aaacagatat accagctttt gcagctatgt
    32821 cagaagaaaa tatagatgtg ataaacgaat ataaaaatga catatgtata gttaagactc
    32881 caaaaaaagg tggaattggt cttaatgatt cattaaataa catatgtaaa ttggcaaaag
    32941 caatagcaaa taaagaagat ataactttga tgaaagaaga gttttgttat caataagagt
    33001 attaattatt agcaagttta aatattatac tatttataat aagcatacat tagtaaaatc
    33061 tatataattt aaggagggga attttaacat gtggggaatg atagcgacat ggagaatggc
    33121 cctagaagga ataactgagg catcagaaca tttagaaaaa ggcatggaag caggtgatgc
    33181 tgtagagctt gctgtaagaa gagttgaaga ctatccattc tataaatcgg ttggatatgg
    33241 tggacttcca aatgaaaatt gtgaggtaga acttgacgct gcatttatgg atggtaacac
    33301 attagatatt ggcgcagttg ctggtataag agattattct aatcctgtca gcatagctag
    33361 gaagttaagt tatgagaagg taaataattt tttagttgga ataggtgctg aagattatgc
    33421 tcataaaaat ggatttgaaa gaaaaaatat gttgactgat agagcgaagt tacattataa
    33481 aaagagaaaa aaagagactt tagacaaagg attaagccca tatgctggtc atgatactgt
    33541 tggtatgata tctttagaca aaactggaaa aatgtgtgca gctacatcaa caagtggatt
    33601 gtttatgaag aaaagaggta gaataggaga ttctgcacta tctggttcag gattctatgt
    33661 tgatagtagt ataggaggag ctacagctac tggtttggga gaagatttaa tgaagggatg
    33721 tatatcttat gagatagtta gacttatgaa agaagggaag catccacaag aagcatgtga
    33781 tattgcagta aatgaacttg ataaacagct tatcaaaaga aggggaaaag ctggtgattt
    33841 atcattagtt gccatgaata ataaaggtga atggggagta gctacaaata tagctgattt
    33901 tactttttca gtagtaacta aagaagaatc tcctactgta tatatttcaa atagagtaga
    33961 tggaaagact atacataagg ttatatcaaa tgagtggatg gaagcatatg aggctagaat
    34021 aaaagcacca atagaagtaa gtgagtaaag tagtggttac ataattaaaa tagagtttta
    34081 taataaggag atttttatga atatcataag taataaaata gatgagttaa aagaagattt
    34141 attaagtgat attatagata ttgtaaaaat acctagtgtc aaaggggagt cagaaaatgg
    34201 cttccctttt ggcgaaaaag taggggaggc acttaataaa gcattagaaa tatcagaaaa
    34261 attgggattt aaggttagaa acttggataa ttatattggt tatgcagagc atggagatag
    34321 tgatgattat gtttgtgtaa ttggacatgt agatgttgta catgaaggag atggttggaa
    34381 gcatcagcct tataagggag aagaaactaa tggaagaatt tatggacgag gagtactaga
    34441 caataaagga cctataatgt ctgccttata tggattatat gctattaaag aattaaactt
    34501 aaaattagat aagagagtta gaataatatt tggtacaaat gaagaaagtg gatttggaga
    34561 tataccatat tatttagaaa aagaaaaagc acctattatg ggatttacac cagattgtaa
    34621 atatcctgtt gtatatggtg aaaaaggcat ggcaaagatt agaataaaaa gtaaaatcaa
    34681 ttatgaagaa gatgtatacc taggttttat agaaaatatg tctgaaaatg tgcttgttac
    34741 atataaagaa ctgaatatag aaaatagtga tactatatta gatataaagg taaaatacga
    34801 ttttagttat aaattgaaag atgtattgga tgaaataaaa gctagttttc caaatagtat
    34861 cgatatagag gtaatttcta attttaatcc tgtatatttt gataaagaga gtaatcttgt
    34921 taaaaagctt cagctagctt atgaaagggt tacatcatta gatggaactc cagtaacaac
    34981 taatggaggt acgtatgcaa aagtaatgcc aaatatagtt ccgtttggac cttcatttcc
    35041 aggacaaaaa ggaatagctc ataatcctga tgaatacatg gatatagaag atataatatt
    35101 aaatgcaaag atatttgcaa atgcaatata tgaattagca aaggagtagt tatgttagaa
    35161 ataataggaa tgtcagtaga agacgctaaa attatagaag attgtggtgc agatagaata
    35221 gagttagtta gtgctttaac tgaaggtgga ttgacaccaa gttttggtct tatagaaagt
    35281 gttgttaaca gtgtaaagat acctgtgaac gtaatgataa gacatcatgc gaaaagtttt
    35341 gtatacagta aagaagatat aagtataatg caaagagata taagtgtggt taaagagatt
    35401 ggtgctaatg gagttgtatt tggtgtattg gataaaaaca gtagtataga tgagaaaaat
    35461 ctaaatgttt tattgaaatg ttgtgataat cttgatgtta catttcatag agccatagat
    35521 gaatcaaata caatagatag tgttaaaatt ttgaaggatt atgataaaat tacgaatata
    35581 ttaacatcag gagggaaagg aagtatagtt gataacatac aaatgataaa gaatatgatg
    35641 cttagttcta atcacataaa aattctttta ggtggaggtc ttaattttaa taatatagaa
    35701 aagataaagg aattgactaa ggcaagtaat tttcattttg gtacagcgat tagaataaat
    35761 aacagtcctt ttgaagatat agatagacaa aagcttaaac aactcgtaaa tataatttca
    35821 agatagtata tgaatataaa atacttagtt taaataaaga gagtaagtta attataattt
    35881 gggtatatga atgttaatag gtattaaata tgaaattatt gttgagtatg ctttataact
    35941 tttaagtagt tttaaatata aataatgaaa gaaaagatag attatggagg ttttagaggg
    36001 tttatattta ttaaaaaatt ataaaggtat attggcatat aatacacata atttcctaaa
    36061 attaccatct tatgacatga attcacatat taataaacaa ttaatggaga tttttgtgga
    36121 tagaaatagg agtaaaaata gctttaaata aacaaaaaca agagttatta acagttttat
    36181 ccacattatc cacaggtgtt tgtaataata ttaatccaca taagtatcaa tgtaactaaa
    36241 aatgataaat aattctatca attgaataga aaaaatcata aaagtaaata ataaaaagag
    36301 gattatgaga gttcgtgtag aatatattat taaagtataa attttcttat actggcataa
    36361 ttgaagggag atgtatttat gaacataatt atatctggaa aacaaatcga attaactgat
    36421 gcaataaaaa ataaaatcga aactaaacta agtaagttag ataattacat tcatccagac
    36481 actgatgtaa aagttacagt gagtgcgaga aaagcaagac aaaaaataga agtaacaata
    36541 gctactgtaa atggtcctat aattagagca gaagatatgc aggaaaattt atacacagct
    36601 atagatgttg tatatgataa attaagtaaa caattaaaaa aatataaaaa gagattacaa
    36661 gataaacata aagacaacaa gagtataaga ttccaagatg cagagataaa tctagctgat
    36721 gaacaagagg attatgggga tgaaaatcaa gaattagtaa ttcaaagacg taagaaattt
    36781 agtgttaagc caatgagtga agaagaagct gtattacaga tggaattaat aggacatgat
    36841 ttttatatgt tcaagaacat agattcagat gaaatagcag tagtttataa gcgtaataat
    36901 ggtggatatg gtataataga acatgaataa agcaatttag atttaatcat attagctatc
    36961 gataaataaa ttatcgatag ctttttaaat taatattaaa agtatagttt ttatggtaaa
    37021 atgaataata gtacaataaa gaacgaggag agatgtaaaa tatgagcttt atggataatt
    37081 tattcaacat ggcagataaa aaagaattaa aaaagttcaa taaaactgtt gatataatag
    37141 attcattaga acctaaattt gaatctatgg cagactcgga acttaaaaat atgacaaata
    37201 tatttaaaga aagattagca aatggtgaaa gtatagatga tatacttcca gaagcttttg
    37261 cagtagttag agaagtttct aagagagtgt taggacttag acactacaga gttcaaatga
    37321 ttggaggtat agtactacat caaggaagaa tagcagaaat gaaaacaggt gaaggtaaaa
    37381 ctttggttgc aactgctcct gtttatttga atgcgcttac tggaaaaggt gtacatgttg
    37441 taacagtaaa tgattacctt gcaaaacgtg atagagacca aatggcaaaa atctatgagt
    37501 ttttaggaat gagtgtaggc gttattatac acggtcaaaa tccaaaagtt agaaaagaac
    37561 aatatgattg tgatataact tatggtacaa ataatgaata tggatttgac tatctaaagg
    37621 acaatatggt aatacacaaa gagcaaagag ttcaaagagg attaaattat gctatagtgg
    37681 atgaggttga ctctatacta atagatgagg ctagaacacc acttatcata tctggacctg
    37741 gagacaaatc aactcactta tattcagatg caaacacatt tgttttaacc ttaaaaccag
    37801 atgattatga attagaagaa aaagataagg ctgtatctct aacagcatcg ggtatacaaa
    37861 aagcagaagt gtattttaat gttgataata taacagatat atctcataca gaattatacc
    37921 atcatataaa tcaagcttta agagcacatg taataatgaa gaaagatgtt gattatgttg
    37981 ctaaagatgg agaaatagta atagtagatg agttcacagg tagacttatg tttggtagaa
    38041 gatattcaga aggtttacat caagcaatag aggctaaaga aggtcttaaa atacaaagag
    38101 aatctaaaac actagctact gtaacattcc aaaactattt tagaatgtat aaaaaacttt
    38161 ctggtatgac tggtacagca aaaacagaag aagaagagtt taaagcaatt tataaaatgg
    38221 acgttttcca agtacctacc aataagctta tggtaagaga agatttacca gattctgtat
    38281 acaaaagtga aataggtaaa tttaatgctg tagcacaaga aataattgaa agacataaag
    38341 ttaatcagcc aatacttgta ggtacagtat cgatagaaaa atcagaatta ttatcacaaa
    38401 tattaaagaa aaaaggcatt aaacatgaag tattaaatgc taagcatcat gataaagagg
    38461 cagagataat agcacaggct ggtagattag gcgctgttac aatagctact aatatggctg
    38521 gtcgtggtac agatatagtt ctaggtggaa atccagactt tttaactaag agagaaatga
    38581 gaagaaatgg atttaaagaa gaaatagtaa atagggtaga tactccaata gaaggtatac
    38641 ctgtaaaagg taatgaaatt ctatttgaag ctagagaaga gtatgaaaaa ctatttgaaa
    38701 agtttaagca acaaacacaa gaagaacaaa aacaagttgt agaagcaggt ggacttgcta
    38761 taataggtac agaaagacac gaatctcgaa gaatagataa ccagttgaga ggtcgtgctg
    38821 gtcgtcaagg tgacccaggg agttcaagat tctatatagg tcttgatgat gaccttatga
    38881 gattgtttgg tagtgataga atatctggta ttgtagataa aataggtctt gaagaagaca
    38941 tgccgataga acatagaata ttatctaagt ctattgaagg agcacaaaag aaagtcgaag
    39001 gtaaaaactt tggaataaga aagcatgtac ttcaatatga tgatgttatg aataaacaaa
    39061 gagaaataat atatgcagag agaaaacgtg tattagaagg tgaagattta caagaacaaa
    39121 tacaatcaat gactcattct ataatagaag aagcagttac tctttataca caagataaag
    39181 gatttgatga agaaggattt aaagaacata tgtataatct gttcttgcca aaaggtagca
    39241 tagaaatacc agaaatagaa aaacttaatc cagttgaaat aacagaaaaa gtttatgaaa
    39301 tagctatgaa gatatatact tcaaaagaag aacaagttgg ctatgagaga atgagagaag
    39361 ttgagagagt aatcttactt caagctgttg ataaccattg gatagaccat atagatgcta
    39421 tggaccaatt acgccaaggt attggtcttc gtgctgtagg tcagcaagac ccagttattg
    39481 cttataaaat ggaaggtttt gatatgtttg atgaaatgaa taaacatatc aaagaagata
    39541 ctgtaagata tttatttaat ataacaatag aaactccagt ggaaagaaaa gcagttgtag
    39601 atgttgaaaa tctatcttct ccatcagatg gaacacttcc aacaagtaaa actgttaaaa
    39661 aagatgaaaa ggttggaaga aatgacttat gcccttgtgg aagtggtaaa aaatataaaa
    39721 actgttgtgg aagataatct cggaggatta aatgttaaag ttacaagagt atagacatag
    39781 tatggagcag atggcttcaa atttagaaga attgagggtt tctctttgac atagcttcat
    39841 tgatgaaaaa tatacaaatt aatgaagaaa agatgaatca acaagacttt tggaatgata
    39901 atgaagtcgc tcaaagagta cttcaagaaa ataaatcttt aaaagagata ttagaagaat
    39961 atgaaagctt aaaaagctta ttagaagata tagaagtatt aattgaaata ggtttagaag
    40021 aagatgatga ttctgtagaa agagatatag aaaagtccat agaatcaatg gaagaaaaat
    40081 tatctgaaat gaaaataaag actcttctaa atggagagta tgataaaaat aatgctatat
    40141 tatctataaa tgctggtact ggtggcttag atgctcaaga ttgggctcaa atgcttttga
    40201 gaatgtatat aagatggtca gaaagtaagg gttataaagt taagctttta gatataatat
    40261 cagaccctga agcagggata aagacagcta caattcttgt agaaggaaca aatgcttatg
    40321 ggtatttaaa gagtgaaaaa ggagttcata gattagtgag aatatctcca tttgacccat
    40381 caggaaaaag acatacttca tttgcatcta tagatgtaac accagagtta gatgaaaata
    40441 tagaagtaga aattaatcca tcagatttaa agatagacac atatagagct tctggagctg
    40501 gagggcaaca tgtaaatacg actgattcag cagttagaat aacacatatc cctactggtg
    40561 tagtagttca gtgccaaaat gaaaggtctc agcatctaaa taaggacaga gctatgagac
    40621 ttttaatggc gaaattgata gaattaaaag agttagagca aaaggaaaaa atagaagata
    40681 tacaaggcaa atactcacaa ataacttggg gtagtcaaat taggtcatat gtttttcaac
    40741 catataaatt ggttaaggac catagaacaa atgctgagtt tggaaatgta gatagtgtaa
    40801 tgaatggaaa tatagacttg tttattaatg aatacttaaa aatgaataaa atagtttaat
    40861 aaatatgcac tgtaattaag atatatgtat aagaaggtta gtgcttaata tgcacttaca
    40921 gcacttaggc tgaggacgat aaccctcagc cttcgttctg ttttgttata cttatgaaaa
    40981 actaacatta ggagtgaata aattggatat aaatcaaatc ttaaaaaaag agtttaatct
    41041 tagagatgaa caaataaata atacattaaa acttattgat gaaggaaata caataccatt
    41101 tatagctaga tatagaaaag aaatgactgg cgaaatgagt gatgttacac taagagaatt
    41161 ttatgaaaaa ttaatgtatt tgagaaatct tcaaagtaga aaagatgatg tagttagact
    41221 aatagatgaa caagggaaat taacagatga aataacacaa aatatagaaa aagcaaaaac
    41281 attacaagaa gtagaagata tatatgctcc atataaacaa aagaaaagaa ctagagcaac
    41341 aatagcaaaa gaaaaaggat tagaaaattt agcattgtca atactagaga ataatttaga
    41401 taatatagaa atagaggcaa agaattatct tgatgaagag aaagaagttc tttctattga
    41461 agatgctcta aaaggtgcta gagatataat tgcagaacta gtctcagatg atgctaagat
    41521 tagaaagtat ataagagaat tagctttaag agaaggtatg atagttagca aaagtgctac
    41581 tgatgagaaa tcggtttatg atatgtatta tgattatagc gaagcagtaa aaagtatggc
    41641 tccacataga gttttggcaa taaacagagg agaaaaagaa agcttcctaa aggttaagtt
    41701 agaaataaat aatgataaag ttttaaatta cataataaac gaatatgtaa atagtaaaaa
    41761 tttcaaaaat aaagaagaaa tcgtaagttc aatagaagat tcttataaaa gattaatttt
    41821 cccatcaata gaaagagaaa taagaaatca tttaacagaa atagctcaag aaagagctat
    41881 aagtgtattt ggaaagaatg ttaaaagttt attgcttcaa ccaccagtta aagacaaagt
    41941 agttatggga tttgaccctg catttagaac tggatgtaaa atagctgtag tagataaaaa
    42001 tggtaaacta ctagattata caacagtata tccaacagac cctcaaaatg atgtagaggg
    42061 agcaaagaaa gttttaaaag gattgattga aaaatacgat atagatataa tttcaattgg
    42121 aaatggtact gcatctagag aatcagaaac ttttgtatca gaaatgataa aagaaataga
    42181 tagcgaagtg cagtatgtga tagttagtga agcaggagca tctgtttatt cagcatctga
    42241 acttgcagat gaggaacatc cagatataaa tgtatcaata agaggagcta tatctatagc
    42301 tagaagatta caagacccat tagcagagct tgtaaaaata gaccctaaaa gtattggtgt
    42361 tggtcaatat cagcatgatt taaacaaaaa gagattagaa gaagtgctag atggagttgt
    42421 tgaagattct gtaaatagtg ttggagtaga tttaaatacc gcatcatact ccctactaga
    42481 acatgttgca ggaataagta aagctatagc aaaaaatata atagcatata gagaagaaaa
    42541 tggagatttt acatcaagag cacaattgaa aaaagtaaaa agactaggac ctcaagcatt
    42601 tactcaatgt gctggattta tgagaatctt agagggtaaa aatccactag ataatacagg
    42661 tgtgcatcct gaaagttatg atatatgtaa aaaaatgatt gagataattg gatattcttt
    42721 agatgatgta aagaataaga atataggtga aatagatgaa aaaataaaag aaattggctt
    42781 gagggaatta agtgaaaaac tggaagtagg acaagttacg ttaaaagata tcatagctga
    42841 aatcaaaaaa ccaggaagag acccaagaga agaaggtata aaacctatac ttagaactga
    42901 tgtcttaaaa attgaagata tacaagaggg tatgacttta aaaggtacaa taagaaatgt
    42961 tgtagacttt ggtgcatttg tagatattgg aataaaaaat gacggattag ttcataaatc
    43021 agaaatgagt aatagttttg tgaaagaccc tatgagtatt gttacagtag gtgatatagt
    43081 agatgtaaaa gtcattggaa ttgacttaaa caaaaaaaga gttgccttat caatgaaaaa
    43141 atagataagt ttatgtatgg ttatagtact taaattctat atttgtaaat gagattactc
    43201 gagtgtataa atgttaaaaa tttgtaaaag tatatagtaa gaaaatatat taaaataaga
    43261 acgatagtct tgaaaatcag gaggaaaatg aatgattttt ataaaaaatg gtaaaataaa
    43321 taccataaca aatgggataa ttcatggaga tatacttata gatgaaggaa aaataataga
    43381 aattggagaa gatttgatag ctcctttaga tgtagaggta atagatgcta gtaataaact
    43441 tgtgtttcct ggatttatag atgctcatac tcacttaggt ttatgggaag atggtatagg
    43501 gtttgaagga gcagatggaa atgaagagac tgacccaata acaccacaat taaatcctat
    43561 agatggaatt aatccaatgg atagaacttt taaagaagct tttgaaggtg gaataacttc
    43621 tgtttgtaca acccctggaa gtgcaaatgt tatgggtggt caatgtatag ctataaagac
    43681 atgtggaaaa agaattgata aaatggtaat aaaaaatcca gttgcatcta aaattgcttt
    43741 tggagaaaat ccaaagagct gttatggtca ggatgataaa tctcctcaaa ctagaatggc
    43801 tatagctgct ttacttagag aaaacctaaa aaaagcagaa gaatatttag aggatattga
    43861 tatgtatgag agtcatgatg atgaagactg tgaaaaacct gaatatgata taaaaatgga
    43921 aagtttaata ccagttttaa gaagagaaat tccttttaag gcacatgctc atagagcaga
    43981 tgatatgttt acagcaataa gaattgcaaa agaatttaat ttaaagctta cattagacca
    44041 ttgtacagaa ggtcatctta ttgtagatga attagtggaa gaagggtttc ctgtaatagt
    44101 agggccatct ttgtcagaaa ggtctaaatt tgagcttaga aatttgacat ttaatacagc
    44161 aggaatactt tcaaatgcag gtcttgatgt atgtataatg acagaccatc cagtaatacc
    44221 agttcaatat cttccaatat gtgcaggtat tgcagtaaaa catggtatga aagaagaaaa
    44281 agcaatagaa tcaattacga taaatccagc taaggcttta ggaatagaag atagagtagg
    44341 ctctatagaa gttggtaaag atgcagacct agtaatttgg gataattctc cactagagat
    44401 tcaaagtaat gtactttaca ctataataaa tggcaaagta gtgtatgaga aaaaataact
    44461 tgacaattat taaaaaatta actaatataa gagtgtaagg aaaattaaaa aatcaaagaa
    44521 gatcttcggg gcagggtgaa attccctacc ggcggtatag cccgcgaact acttaggtgg
    44581 ttgatttggt gagattccaa agccgacagt aaagtctgga tgagagaaga tatttatgga
    44641 agataaataa gtttatttta gtttgtttaa actatatcca taaaaactcg aagatagggt
    44701 cttcgagttt tttgtttttc ctaaaaaata taaacatatt gattaggggg aaaataatta
    44761 tgcaaaacac agcaaaaaga ggcaatatga tttcaacaag aactttagta gtaatgtcaa
    44821 ttttatctgc aatatcttat ttattaatgt ttattcaagc accaatacca ggtatatttc
    44881 cagatttctt aaaaattgac ttatcagata ttccagcaat attcggagga atgtctctag
    44941 gaccattagt tggatttgga atagttgtag taaaaaatgt gttacaagca ataacagcaa
    45001 caacaactgg aggaatagga gaatttgcaa atatattaat tggtggttct tatgtaatga
    45061 tactttgtta ttcatataag agaagtggag atttaaaagg tgtactgatt ggttttgtat
    45121 taggaacaat atctatgact ataattggtt cattagtaaa ttattttgta atgttgccac
    45181 tttatggtca acttatggga ctagatgcta taataggttt aggttcagct ataaatcctc
    45241 aagttcatga tttattcact tttgtaattt ggatgatagc tccatttaat gtgctgaagg
    45301 ctgttataat atctttagta acattgccac tttataaaaa aatgggaaat ataataaaga
    45361 aataattaga caagaaaata taaaattaaa tgtattgaat agccataatt tatttataac
    45421 ttcagtccta tattgtgatt gatatattaa atatattatg gctttattaa tttatcaaaa
    45481 aatgtatata aaataagaaa tatttagaca aatttaaatt ttaaaataaa ggaagaatta
    45541 aaacgattaa ctattaaaat atgaaaaagg tatctacaat atacagagcg aatttataat
    45601 aaacaaaaaa taaagttatt attaaaaaac tataaagatt aataatcaaa cttttaataa
    45661 taactaattt aataatgata ggggtgtata ttcatgcatt tatctaaaaa aataaaaaaa
    45721 ttatttttag atgataaagg gtattatttt aatagtaatt ggaaagatat tcatattggt
    45781 atttatgata caaaattagg agattcttta aagtatatca ctaatgaata tattgaaaat
    45841 atggaaaggg taaaatacga ttatcgtgaa ttaaaaaata tagaaaatca aactgatggt
    45901 atgtgtattt tagcaataag gcagaattac aaggcattag agtatgtaaa aaatcaaacc
    45961 gaagaattat gtttagaagc aataaagtat aattataaag cacttgaata tgtaaaagaa
    46021 caaacagaat acttgtgtct tgaagctata aaaaaagatt gtaatgcact taagtatgta
    46081 ctaaataaaa cagaagggct tattataaaa gcaataagtc attcttccaa tatagatgtt
    46141 gtaagtatac taaaggcttt agagactcaa acaagaagga tatgtttaga agcaattaaa
    46201 aaagatggca ggtgtcttgc atacgttaga gaacagagtg aagaattatg tatagaggcc
    46261 attaagcaaa attataaagc attaaaatat gtaaaaaatc aaacggaaaa aatgtgtata
    46321 gaatccgtaa gacaaaatgg tatggcatta caatatgtaa ataaacaaac tgataaaata
    46381 tgtatagaag ctgtcaaaca agatggaaga agtatacaat ttgtcaacaa taagacagaa
    46441 gaaatatgta taaatgctat aagatattta aataaaaaat ataatattaa agatgtacta
    46501 agttacatag ataagtatac agaagatata tgtatagaga ttgtaagaca aaatggaaaa
    46561 atgcttatgt atataaaaaa tcaaacagaa aaaatgtgta ttgaagcagt aaaagagaac
    46621 tataagtctc ttaagtatgt aaaagagcaa tctgagagaa tatgtaaaga agcattgaag
    46681 caaaaccata aagcaaaaga gtatgtaaaa attgctattg atgattgtat ataaggtgta
    46741 gatacagcca tcaatagtga aagataaaaa aagataaaga caagtacttt ataataatct
    46801 aggcttatac tataattaat taagcagtga tataaattca catgacgatt atatcaaaat
    46861 ggagatgaat tgatggcaaa aatatattta gaaaatgaaa ataaaactag agaaatagga
    46921 tataaattag gtaaactttt aaaagaaggc agtgttatct gtttagtagg agatttagga
    46981 gctggtaaaa ctacaatgac acaaagtttg gcagattcat tagggataga agattatata
    47041 acaagtccta cttttactat aataaatgaa tatgaaggaa aaataccttt gtatcatttt
    47101 gatgtttata gaataggtag tagtgatgaa atgtatgata ttggttatga tgaatatgta
    47161 aattcaaatg gaatctgtat aatagaatgg gctaatctaa tagaagatat acttccaaaa
    47221 gaatatttga atatagaatt gagatataaa gatgaaggaa gagaaatgat attaactcca
    47281 aaaggagagt tttataaaga gatagttgag gagttgatta aataatgaaa atactaggta
    47341 tggatacgtc ttctatggca gcaagtgtag cagttgttga agatgataac ttaatatgtg
    47401 agtttacagt aaacaacaaa aaaactcatt cacaaaagct tatgccaatg atagaaaata
    47461 tgttgagtat gagtgattta agtataaaag atatggattt attagctgta tgtataggtc
    47521 caggttcgtt tacaggactt agaataggta tggctacagt aaaagctatg gcccatgtaa
    47581 ataatatacc aataatagca gtaaattctt tggaatctct agcaaataac ataaatttct
    47641 gtgatagaaa gatatgttgt atattagatg cgcagaaaaa tcaagtttat tcagctaaat
    47701 acaagtttga aaatggagag atgatagaat tagatggtgt tgatgttgta gagtttgatg
    47761 ctttagtaga tgaaattgta tcaactaatg aagaatttat aatagttgga gaagctgtat
    47821 acaaatataa agacaagcta gagaatataa aaaatataaa aataccttca ccagctaata
    47881 atgtatctaa cgcaggaagc ttatgctctt tagcattaaa taaatataat aaaaatatag
    47941 atgtacatac ttgttatacg ataaatccta tgtatatcag aaaatctcaa gctgaagtac
    48001 aatatgatga aaaaatgaag aggctaaata atggaagata atacaaaact aatagtagat
    48061 gatataaaaa tagaagaaat gactacagaa gatatagatg aagtttttga agtagaaaaa
    48121 aattgttttg aagattattg gtcaaaagag tcttttagaa aagagttgtc taatgaagta
    48181 gcaaggtata tagtagctaa gttaaatgga aaaattgtcg gatatgtggg aatttggctt
    48241 atacttgatg aagggcatat aaataatgtg gctgttcata gtgactatag agggaaaaaa
    48301 ataggggaca agttgataaa aggcatagtt gatttatgta aagataataa tattgcatct
    48361 atgacattag aagttagagc atcaaataaa atagcacaaa atttatatag aaaatatgga
    48421 tttaaaatgg gtggaataag aaaagaatac tacagtgata ataaagaaga tgcaattata
    48481 atgtggaacc aattaaaaga ggtgtagagt ttatgagtga tataataaca ttagctatag
    48541 agagtagttg tgacgaaaca gctgcatcag ttttaaaaaa tggtagagaa atactttcaa
    48601 acataatctc tactcaaatc gagacacata aaaaatttgg tggtgtagtt ccagaagtgg
    48661 cctcaagaaa acatgtggaa aatattgata tagttgttca agaagcttta gacaaagcaa
    48721 atataggttt taatgatata gaccatatcg cagttacata tggacctggg ctagtaggtg
    48781 ctttattggt tggtctatct tatgctaaag cacttgcata tactttgaat attccacttg
    48841 taggagtaaa tcatatagaa gggcatctaa gtgcaaacta tatagagcat aaggatttaa
    48901 aacctccttt tataacatta atagtatctg gaggtcatac tcacttggtt gaagtaaaag
    48961 attatggcaa gtatgaaatt ttaggaaaaa caagagatga tgcatctgga gaagcatttg
    49021 ataagatttc aagagctatg aatttaggct atccaggagg tcctattatt gataatctgg
    49081 ccaagaatgg aaataaacat gctatagaat ttccaagagc ctatttagaa gaagatagct
    49141 atgattttag ttttagtgga ttaaaatctt ctgtattaaa ttatctaaat ggaaaaagaa
    49201 tgaaaaatga agaaatagta gttgaagatg tagcagcatc tttccaagag gctgtagtag
    49261 aggttttatc tactaaagca ctaaaagcag taaaagacaa aggatacaat atcataactc
    49321 tttctggtgg ggttgcttct aattcggggc ttagagctaa aataacagag cttgctaaag
    49381 acaatggtat tactgttaag tatcctcctc taattttatg cacagataat gcagctatga
    49441 tagggtgtgc aggatattat aattttataa atgggaaaac gcatgatatg agtttaaatg
    49501 cagttccaaa tttaaagata aatcagtaga gttagatgaa tttgtaaata taaaagtatt
    49561 gtttcaaaaa agtaagtaga agtgaaatta aatataataa aaataaatat agtatatatt
    49621 aaaacttgaa gtaaaactat ttataatctt tatattccaa tgaattgcaa caaattttag
    49681 gatatacaga ttgtctttgg cttagatttg cttcaagttt aattttttct atagaaagat
    49741 tattttaaaa agtgggtaat ataccctttt ttttcattct taaaaagttt tatactaatt
    49801 atagaaagat taaggagggg aagaaatgag tcaaagtaaa gaagacaaaa taagaagtat
    49861 tttggaagca aaaaatatta aatcaaattt tcaaaataaa gaaaatttaa gtgaatttaa
    49921 tgaaaaaaaa gcaagtaaaa gagcagaaga cttattagat gtatattata atacattatc
    49981 tactgctgat atggaatttc catattggta taatagagaa tatagaaaat cagatggtga
    50041 tataccagta gttagaagag ctaaagctct taaagctgct ttttcacata tgacaccaaa
    50101 tataatacct ggtgagaaaa tagtaatgca aaagacacgc cattatagag gttcttttcc
    50161 aatgccatgg gtaagtgaaa gtttctttgt tgctcaagga gaacaaatga gagaagaggc
    50221 aaagaaatta gccagtaaca cagctgatga acttacaaaa tttgggtctg gtggaggaaa
    50281 tgttactgaa agttttggaa atgtcgtttc aatagctggt aaattcggaa tgagaaaaga
    50341 agaagtacct gtacttgtaa aaatggcaaa ggaatgggtt ggaaagtctg ttgaagattt
    50401 aggttttcac tatgaaaaaa tgatgccaga ttatgattta aaagaaaacc taatgagtac
    50461 acttatatgc atgtttgatt cagggtatac acttcctcaa ggtagagaag ttataaatta
    50521 tttttatcct ttaaattatg gattagatgg aattatagaa atggcaaaag aatgtaaaaa
    50581 ggcagttgca ggaaatgcat ctggagatgg gcttattggt atggaccgtc tatattttta
    50641 tgaggctgtt attcaagtta ttgaaggatt acaaacttgg attttaaatt atgcaaaaca
    50701 tgcaaaatat ttagaaagta tagagacaga tttagaagct aaaaaagaat actcagattt
    50761 agtggagata ttagaacata ttgcacataa acaacctcgt acatttaggg aagctcttca
    50821 gttgacttat acaattcata tagcatcagt aaatgaggat gctatatctg gtatgtctat
    50881 aggacgtttt ggtcaaattt tatatccttg gtatgaacaa gatatagaaa aaggactaat
    50941 tacaaaagaa gaggttatcg aattattaga gctttataga ataaaaatca cttgtattga
    51001 ctgttttgct tcagcgggcg taaatggagg agtactatca ggtaatacat ttaatacttt
    51061 atctataggt ggattaaaag aagatggttc tacaggagct aatgaactag aagagttatt
    51121 attagaagca agtatgagat gtagaactcc tcaacctagt ttaactatgc tatatgatga
    51181 aaagcttcca gaagatttct taatgaaagc tgctgaatgt acaaagcttg gttctggtta
    51241 tccagcctgg gtaaacaact caaatggaac aacatttatg atgaaacaat ttgctgatga
    51301 aggtatgact gttgaagaag caagagcatt tgcattaggt ggatgtttgg aaacgtctcc
    51361 agggtgttgg aaacagttaa ctttaaacgg aaaaacgtac tctattgcag gtggagcagg
    51421 tcaatctgct ggctctggag ttcactttat agctaatccc aaaattttag aacttgttct
    51481 tatgaatggt aaagaccatc gtatgaatat acaagtattt gagcctcata ataagccatt
    51541 agatacttat gaagaagtca tagaagtatt taaagattat tataaacaag caataaatgt
    51601 tttagaaaga gcaaataaca ttgagttaga tatatggaga aaatttgata cttctataat
    51661 aaattcacta ctaaagccag actgtttaga caaaggtcaa catataggaa atatgggata
    51721 tcgttataat gcaacattaa acgtagaaac ttgtggtact gttactatgg tcaattcatt
    51781 tgcagcactt aagaaacttg tatatgatga caaagcattt acaatagagg aaatgaagga
    51841 tgcaatatta aataattttg gatttaaaga tgcattagaa gtaggaaatt attctatggc
    51901 agaccaagta aaagtagata agactggtaa atatgatgct atttacaagg cctgtcttga
    51961 tgcacctaaa tatggaaata atgatttgta tgcagataat attcttaaaa actatgaggt
    52021 atggttatca aaagtatgtg aagaagcaca atctttatat gctaagaaga tgtacccttg
    52081 ccaaatatct gtttctacac atggaccaca gggagctgct accttggcta ctccagatgg
    52141 tagactaagt ggaacaacat attcagatgg ttcagtctct gcatatgcag gaacagataa
    52201 aaatggagta tatgcattat ttgaatctgc aactatttgg gaccaagcag tagttcaaaa
    52261 ttctcagatg aatttaaaac ttcatccaac tactataaaa ggacaacaag gaactaaaaa
    52321 attattagat ttaacaagaa gttatttaag aaaaggtggg ttccatattc aatataatgt
    52381 tgtagattca gaaacattaa aagatgcaca aaaaaatcct gacaattatc gtcaattaat
    52441 ggtacgtgtt gctgggttta ctcaatattg gtgtgaatta ggtaaaccaa tacaagatga
    52501 agtaattgct agaacagagt atgaaggggt gtaaaatatg agaaagcata gtgattgtat
    52561 gaatttttgt gcagtagatg caaccaaagg aatttgtaga ttatcaaaac aaatgattaa
    52621 tttagatgat gcagtatgtc cagagataaa agtaatgcca aaatgtaaaa attgtaaaaa
    52681 ttttgttgaa gctaatgatg aaggtatagg caaatgtgtt ggcctagaga aagaagactg
    52741 ggtatattca acattgaatg caattacttg tgaaggacat gtgtttaatg agtagtcaaa
    52801 agcaattaga aggcatgatt ttcgatgtac aaagcttttc agttcatgat ggtccaggtt
    52861 gtagaacaac tgtattttta aatggatgtc cactgagttg taaatggtgt gcaaatccag
    52921 aaagttggac tgtaagacca catatgatgt ttagtgaatt atcttgtcaa tatgaaaatg
    52981 gatgtactgt atgtcatggt aagtgtaaaa atggtgcatt gagctttaat cttgataata
    53041 agccagttat agattggaac atctgtaagg actgtgaaag ttttgaatgc gtcaactcat
    53101 gttattataa tgcgtttaaa ttatgtgcaa aaccttacac tgtagatgaa cttgtgcagg
    53161 taattaaacg tgattctaac aattggagaa gtaatggagg agtaacattt agtggaggtg
    53221 agccactact tcagcatgaa tttttacatg aagtattatt aaagtgtcat gaggtaaata
    53281 tacacactgc cattgaaacg agtgcatgtg tatcaaatga agtttttaat aaaatattta
    53341 aagatattga ttttgcattt attgatataa agcatatgga tagagaaaaa cacaaagaac
    53401 aaacaggtgt atataatgat ttaatattag aaaatatatc aaaccttgca aattctgatt
    53461 ggaatggaag attagtactt agagtaccag ttatctctgg gtttaatgat agtgatgaaa
    53521 atataagtga tattatatct tttatgcaca aaaataattt ggtagaaatt aatctattac
    53581 catttcacag attaggagaa tcaaaatgga ctcaattagg caaggaatat gagtattctg
    53641 ataagggtga tgttgatgaa ggtcatcttg aagaattaca agatatattt ttggataatg
    53701 gtatagcttg ttatgttggt catgagacag ctttttaaaa tcaaatacaa gttttaatta
    53761 aaaaaaggat gttacactaa aagctagagt tacatccttt tttatgtggt ttttatgtag
    53821 aaataattaa gtaaagtttt atatattgtt tatattgctt tatgtccata aatattgctt
    53881 taaatatact ttatacattt tttatagttt aaattacagt tagagaatat attacgttta
    53941 ctttattgaa gcagaagttt tgtggtaaaa tactactatg aaaaaattta atagaatata
    54001 ttttagaaac aactaaaaat aatagttagg aggaagacat ctatatgaac aaatcatgga
    54061 gcaacttgat tattaagaat aaagacagaa aagtacgttc agggtggatt attatagctg
    54121 ttatggctac cttttacata cttcagtatt atttaagcat gacacttgtg gaaataataa
    54181 gaaaaattct gattgcgaca ggtgatatta atttaaaaac aaactatttt tcagaatatg
    54241 ctaattgggt aagtgatgtt gggttacagg ttgtatttca aattctaaca gattcactta
    54301 tgattattat tcctataatt gtatggagat ttattatgaa aaatcctatt agtgaaatgg
    54361 gattacattc ttatagaatt aagaaaaaag aaggatatgt aggaatgtta ttaggaatat
    54421 ttaattgtac agtaatcttt attataacaa taacaattgg tggtggtcat gttacttcat
    54481 gggtaccaaa aatttcacct ttaacagttt cttggatact tgtctttatt ttagttgctt
    54541 ttgcagaaga aattttaaat cgtggttttt ttatggcagt tttacgaaga tgtaaaaata
    54601 tttattttat aatgattgtt ccatctgtta tttttgggtt gattcatata tggaatcctg
    54661 atgttacttt tttgtctgta attaatatta taattattgg gattcttttt tcatatatgt
    54721 ttataaagtc gtcgaatata tggatgtgta taggttatca ttttacatgg aatgtatttc
    54781 aggggattat atatggtatg cctgtaagtg gacttcaggt tccagggatt ataactacac
    54841 aaattactaa tagtaattta ttaaatggtg gtatgtttgg tattgaaggt ggaattttga
    54901 ctacttttgt taatctactt agctttatat ttgtatggta ttactataga gattctaagt
    54961 atgattttgt tagtgataaa gtaaatgtga ccaatatcaa gaattagttg attataataa
    55021 attttaataa tatcttctaa gcttaaagta ttctgtagga ttgttggaaa tttgcaaaaa
    55081 tataaaaata acttggatat tctatttact ccaagttatt tttatattct tttgtaaata
    55141 gaaatggaac ataaaaaatt aaaacaacca tagatactat tagtatatca tggtaagtga
    55201 tagttgattc tttagaattt gtgataagaa aagcactatt atttaaaaca tgaattatag
    55261 cacaaaacca gatattctta gttttcatat aaagatatcc taaaaatatt gaaattccaa
    55321 ctatatgtat tgaacgtaat attactccta atattggcgc ttcaggtgta tataatgtaa
    55381 atattagtgg taagtgccac aagctccaac acatacctaa tattataact cctaattttt
    55441 taccaaattt atcaaaaaaa atattctgta aaaaacctct ccaggcatat tcttcactaa
    55501 aaaaaatata aatagtagtt aatgatgtta ttggagtaaa tataaatttt atgataccac
    55561 tataattagg ttgagcccct tgtagtatta gtataaatga tgttggaaca attacagaaa
    55621 tcataaagta aataattaat aaagaaccta gtttaatatt ttttacagga tataaatttt
    55681 ttttatttga tgaatatatt ataattgata agctacttat aaaagttaat attaggttta
    55741 taattataaa ttcattatta tttattagat ttaataactt aagaacaatt aataatgaat
    55801 aaataaaaaa aaataatatg attagtgaat aaaattcata catatcatta tttaatcctt
    55861 cagtataaaa ctttgcaata gcaactgaag atagaggtaa tatcatcatg aatgatgcaa
    55921 agttttctgg atcaataaat ttattataat ataacagtaa acctaatgaa taagttaaac
    55981 caaagtttat aaagaaaaag ataataattt gtattttttt tctttttatt tcatttttaa
    56041 taaatactgg gtttagaata tttatccata ttaattttaa gttcattaat ttaatactcc
    56101 tttacaatat agattcttaa ctaaattaaa atattttatt gaatattata aattcatgac
    56161 agtcaata
//
LOCUS       DACTZW010000018        54545 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.018, whole genome shotgun sequence.
ACCESSION   DACTZW010000018 DACTZW010000000
VERSION     DACTZW010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 54545)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54545)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54545
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.018"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(401..3508)
                     /locus_tag="JAM15_05760"
     CDS             complement(401..3508)
                     /locus_tag="JAM15_05760"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HAT6797761.1"
                     /translation="MAKFKPLVDSSVKQAEAQVFDYWKDINILEKTLEKGKDDPSFVF
                     YEGPPTANGNPGVHHVLSRTLKDSVCRYKTMSGYQVKRKAGWDTHGLPVEIQVEKELG
                     LTSKQQIEEYGIAEFNQKCRESVFSFEKQWRIMTERMAYEVDLDNPYITLDNNYIESV
                     WWILNKFNKEGYIYEGHKILPYCPRCGTGLASHEVAQGYKEVKTNTVIAKFKKKDADE
                     YFLAWTTTPWTLPSNVSLTVNADVDYLKVKKGDEVYYVSKPLADKVLGEDYEVLEEMK
                     GKDLEGLEYEQLMPFVEVDKKAFFITVGDYVTTEDGTGIVHTAPAFGEDDYNTGKRYD
                     LPVIQPVDETGKFTSTPWEGRFVMEDGLDVEIIKWLASENKLYSKEKVVHNYPHCWRC
                     QTPLVYYAKPSWYIEMTKLKDKLIENNNGVKWFPSFVGEKRFGNWLENLNDWAISRTR
                     YWGTPLPIWRCECGHTDSVGSRAELAEKAIEDVNPETVELHRPYVDDIHLKCEKCGKP
                     MTRVTEVIDCWFDSGAMPFAQHHYPFENKENFDQLFPADYISEGIDQTRGWFYSLLAV
                     STFVLGKAPYKSVLVPDLVLDKDGKKMSKSRGNTVNPMELFDQYGADALRWYLLYVSP
                     PWTPTKFDMDGLKEIQSKFIGTMKNVYNFFTLYANTDDINPTEFFVEYKDRPELDRWI
                     LSKFNNLMKDVEENLAIFELNKTLRMIQDFINDDLSNWYIRRSRRRFWATELTEDKKA
                     VYNTTYELLHGLCRAIAPFAPYMSEEMYRNLTGEVSVHLAEYPKCNEELVDTKLEEKM
                     DLAKNLVTLGRASREVERIKVRQPLQKVLVDGKFEDTISDVVDLIKEELNVKEVIFAK
                     DLDEYMNFSLKPNFKEAGPLLGSKMNLFVGALSKLNAHETANKLEKGETLTVDLDGEA
                     FEFNKDLVLIGITAKEGFNVSVENNLFVILDTKLTEELINEGYAREFISKVQQLRKSN
                     NFEVLDNIVIEYCGDDEIAKAVDHFNEYIKSETLALEINRVDDKSLEEQNLNDHMTGI
                     KVIKK"
     misc_binding    complement(3601..3833)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(4008..4535)
                     /locus_tag="JAM15_05765"
     CDS             complement(4008..4535)
                     /locus_tag="JAM15_05765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HAT6797762.1"
                     /translation="MLTPIEIENKEFKKGLRGYRDEEVDEFLDIIKEDYESLCRENTA
                     LKEKLGLYQDQVNKYENIEETLKATLITAQSAAEDTCSAANKKAKIIVEEADLKARQI
                     IEQANNRVIEIRKEYDALVKEFKIFRNKFKSLLEDEIRSVDEIFYDVDEKCVNAFEGT
                     TVYNYSNDEAATTLE"
     gene            complement(4570..5355)
                     /locus_tag="JAM15_05770"
     CDS             complement(4570..5355)
                     /locus_tag="JAM15_05770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HAT6797763.1"
                     /translation="MDKLKLTNHIKDIDLKNKMFKVIDKANSCIKNYDVKSTEFLNPY
                     EVKNAVAILNSTNEIKYSVDGGYEQAERSTVFIYPFYMEYEDIEDTLRFLQIEGNFKF
                     KNISHKDYLGSILGLGIKREKIGDIIIHDSFCQVVVSSDICDFIIVNLEKVSRNNVIV
                     KEISRENIVNSSSKYKEVSFTVSSDRLDCVISGIYNISRQDSAKYINGEKVHVNYEKI
                     TSTSKIVKNDDLISIRGKGRAKVTQIGDITKKGKIKVQARLIV"
     gene            complement(5365..5622)
                     /locus_tag="JAM15_05775"
     CDS             complement(5365..5622)
                     /locus_tag="JAM15_05775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HAT6797764.1"
                     /translation="MGTIRIALYYLLDIIAWMIVIKSLMTWFPNGRQSKIFNILENLT
                     EPIEGPIRSIMYKYTNGPIDFSPLIAIVLLMFLRQLVLVIF"
     gene            complement(5641..6099)
                     /locus_tag="JAM15_05780"
     CDS             complement(5641..6099)
                     /locus_tag="JAM15_05780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HAT6797765.1"
                     /translation="MSNGIISKFKNWIVDEEEDYIEDEYESGMDDIVQEEEMNSGFST
                     AKANKIVNLHTTSQMKVVIVEPKVYDEAATIADHLKQRRAVIVNLEGLTNSEVRKSIF
                     NFMNGAVYVLDGSIQKVSKSIFILAPNNVDIDANMKKELESKAFFPWQNK"
     gene            complement(6139..6843)
                     /locus_tag="JAM15_05785"
     CDS             complement(6139..6843)
                     /locus_tag="JAM15_05785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HAT6797766.1"
                     /translation="MGSIKDNLSEIRNKIDKAAKKVDRDSKEITLLAVTKTVDVDLVN
                     EAMREGITSVGENKPQELARKYDIIGDKLNWHLIGTLQTNKVKYIIDKVCMIHSLDRI
                     ALCEEIQKRAEQINREIDCLVQVNISKEESKHGLDREEVVDFVKEVSEKYKNIKIKGL
                     MTMAPFIEDEDEIRGVFKGLKDLSKQIKELNIPNVGMDVLSMGMSHDYEIAIEEGATI
                     VRVGTSIFGERNYNKK"
     gene            complement(6853..7488)
                     /locus_tag="JAM15_05790"
     CDS             complement(6853..7488)
                     /locus_tag="JAM15_05790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797767.1"
                     /translation="MKKVKYTRLVILGILIYLVFNILVMIISKNVDTLVLKNEKVNAK
                     IHVKGTIEKDANDQSNYLSTYISKEDSNNFEKNQNVIIEYHEQKLDAKVYKIYENNNK
                     IMVKLKISNQIVANQDTSVEEFDIIYNQMECLKIPKTSIKTKDNKRGVYVIDEQSQSV
                     KFVILEGITYENESSVFVDYYKNDINGVTSVNLYDKIILRPNSINTNIRIK"
     gene            7869..8909
                     /locus_tag="JAM15_05795"
     CDS             7869..8909
                     /locus_tag="JAM15_05795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAT6797768.1"
                     /translation="MSEILLGTGLLLLVLCCFTIFSYKAPYGMKAMGALANAACATFL
                     VEAFNLSLLGDVLGMEFFRSVGAANGSLGGVAAAILVPLALGVSPVYAVLIGLSCLDF
                     SILSGFVAGYFVSFLIKFIEKKVPPGVDLVVVILLCAPLSRLIASNVDPLVNSTLLQI
                     GQVLIEATNISPIIMGIILGGLITVVGTSPLSSMALTSIIGLTGLPMAIGALGAFGSA
                     FMNSTLFAKLKLGSKKDIISVAIEPLTQSDIISANPIPIYSTNFFGGAFSGIIVALMG
                     LVNMTPGTATPVAGFAIMFAYNPVQQVLITAGLCALFNVIAGFLGSKIFSTFKVLTAG
                     EIRGTDVEEEIA"
     gene            complement(9360..10715)
                     /locus_tag="JAM15_05800"
     CDS             complement(9360..10715)
                     /locus_tag="JAM15_05800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009170073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HAT6797769.1"
                     /translation="MNVGNILETIKMIDEEQLDIRTITMGISLLDCIDPDGDKAREKI
                     YNKIMSSAKDLVKVGKDIEREFGIPIVNKRVSVTPISIIAGATDENDYVKFAQTLDKA
                     AEDLGIDFIGGFSALVQKGYTKGDKILIKSIPKALASTNKVCASVNVGSTRCGINMDA
                     VKEMGEIIKETAELTKDAKGFGCAKLVVFCNAVEDNPFMAGAFHGVGEADRIINVGVS
                     GPGVVKRALEKVKGEPFDVVSETVKKTAFKITRVGQLVAKEASSRLDVPFGIIDLSLA
                     PTPAIGDSVANILEEMGLEVVGTHGTTAALALLNDAVKKGGVMACSHVGGLSGAFIPV
                     SEDAGMIDAVIKGALSIDKLEAMTAICSVGLDMIAVPGNTTAGTLGAMIADEAAIGMI
                     NNKTTAVRIIPAPGCDVGDMVEFGGLLGRAPVMPISTNSSELFTQRGGRIPAPIHSFK
                     N"
     gene            complement(10741..11010)
                     /locus_tag="JAM15_05805"
     CDS             complement(10741..11010)
                     /locus_tag="JAM15_05805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016207686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HAT6797770.1"
                     /translation="MKAILTVIGKDKPGIVAGISDELYKQNINIVDISQKILQDYFTM
                     IMIVDLEKSLNSFEKTVEDLVERGKKLSVDVKIQREEIFNSMHNL"
     gene            complement(11300..13240)
                     /locus_tag="JAM15_05810"
     CDS             complement(11300..13240)
                     /locus_tag="JAM15_05810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797771.1"
                     /translation="MKKYEIFIFMSIIVLCFISFPHKVFGQEENCLEDFERWVQENKN
                     NKEEIVYTLSCDMVIDEEFRFYIPYDSNFTIDTNKYKILIKNHGRFIIDDNELNIIGE
                     GGKEGVIHIENGGSISIGINNIIATDGTALYVEEGGDLHIKSSYESVEKIKANGKDAI
                     GIYTENDIRILNKDIEVNGEHAIGVYSKGDVEIEETSIKAYSSNNESGLLRDNNKLAQ
                     SIISESKKVYIIDDYNELIPSIAKDSGYNIVKCCHRGIGVFSDEIKVSKDDKIENIKF
                     PKYMVLETSSGNQLDIDVEWDFNDYYEKLEKGENFDITGKFKTEMLNKEKIIINDDVV
                     PILNVSVIEKKTIDNLELEFQNTKNGYVAVLFYDMPYSASKVFVEYSSDGINWISEEQ
                     EDIRDQAILFFEDFKLRCFRVKVVGGLKEGYSNIVFKPGFIMGGGDNQETPDDEREND
                     DIDGDRGGGGRDDPDRDEDDNNQDGNNGNENNDSNNNQNNNNENNNSDEKQPNTPKDD
                     VESSTDSNENKNPHDIPKDGNKENNSDKEKGFYNKNPITENDDNYDLSSKSVFGTNEH
                     SFPYRESISNKNQDTNKNKSNISDYDGIINNNYKLESKEYNLKKDIIFLFCILTPIMI
                     GSILIVNPDTRKSIIKFIKLKK"
     gene            complement(13424..14899)
                     /gene="spoIVA"
                     /locus_tag="JAM15_05815"
     CDS             complement(13424..14899)
                     /gene="spoIVA"
                     /locus_tag="JAM15_05815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage IV sporulation protein A"
                     /protein_id="HAT6797772.1"
                     /translation="MNNNIYEDISKRTQGDIYIGVVGPVRTGKSTFIRKFMEKLVIPN
                     IDNEFKKDRTRDEIPQSGSGKTIMTVEPKFVPADGVEIKIKDTVSLKVRMVDCVGYIV
                     EGALGHEEGGKQRLVSTPWSQEAMTFEKAAEIGTKKVIKDHSTIGIVVLTDGSVTGID
                     RKSYVEPEERVIQELKNLKKPFAVVLNTLSPKSEETSMLRSELEEKYEVPVLPMNVVE
                     MEEEDIEEVMEAVLYDFPLTEIRINLPKWVEGLERNHWIKSSIITTLKQSIIDIGKIR
                     DIEGIIQGFSELEFLEDTGVDNVELGEGVINIDLQTKQDLFYNVLEEKSGFKIEGDYQ
                     LLSLITRLSKVKNEYDKIESALIDAKIKGYGVVAPSLEELSLEEPEIMKQGKQYGIKL
                     KANAPSLHIIKADISTEVSPIVGNQNQGEEMIKYLMEVFEEQPADLWESNMFGKSLHD
                     LVKEQLQSKLYTMPEEIRVKMQKTLQKIVNEGSSNIITILL"
     gene            complement(15071..16366)
                     /locus_tag="JAM15_05820"
     CDS             complement(15071..16366)
                     /locus_tag="JAM15_05820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAT6797773.1"
                     /translation="MSVEVNKPSIWKNFKVLIILFVAGAFIYALPYLKNYYYDTFAQA
                     FNLTNTQMGSLGSIYGLLAMVSYLFGGFLADRISARKLLSGSLIITGISGLVLTLYPP
                     YIVVFLIHALWGITTILTFWPALVKAVRMLASENEQGKAFGFMESGRGITNAIHLSLV
                     LILFGYISSKVSDKSGLTAIIVLYSAINVIVGVLVFFKLKDNEKEVSAKFDKEAFFAV
                     IKMPHTWIITIIMFCSYSANMSFYYFTPYSTEAFGATVVFASAISILAQYCRPVASAA
                     SGLLGDKVGSSKIISYGFILMIAGLLGVIFTPTKSSMIYILLIGCVAIYVSMYAIQGL
                     HYSLLEEGNYSLSISGTAIGIVATLGYLPEVLCPLAAGKILDAFPGVTGYRYYFIVLT
                     IVAIIGLVFTFIWMNMTKERRKELIEMNNKSNENTTKVS"
     gene            complement(16550..17959)
                     /locus_tag="JAM15_05825"
     CDS             complement(16550..17959)
                     /locus_tag="JAM15_05825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAT6797774.1"
                     /translation="MKKKIGFWDLVFMNISALFGIRWIAKSTASSFGLGLGSIPVWLL
                     FAFIFFVPASLICAELAATYPKDGGLGEWVKQAYGEKWGFMVSWLNWTSKIFWYSSFL
                     TFLAINIAYMLGNPDLSNNKMFILALSLIIFWLLSLVSTRGMAFGKFFTNTGALGSTI
                     PAILLIVMAFMSVVILKKAPSASIYTIQNIIPKIDANSLVSISAIIFALSGAETTANF
                     ITEMDNAKKNFPKAILTVAVLIGGIYILGSVAITMILPPDKIAASTGILDALAKVAQD
                     LGIGSWFIRIVAFGITLSVLGALILYIAGPVKMLFGNVREGVFPKQLTVTNKYNIPSN
                     AVIVQAIIVSLLLVGTNLLPSVDNIYNVLVTMTALTALFPYVLLFTSYIRLRKTRPNE
                     ERPYSIAKSDSVCINIARMVLVVTVVGILFSTAPVMETLKDNIIYEIEMIGGGLFVII
                     TGLMLWKNYEKKISNNSGR"
     gene            complement(18011..19150)
                     /locus_tag="JAM15_05830"
     CDS             complement(18011..19150)
                     /locus_tag="JAM15_05830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HAT6797775.1"
                     /translation="MSNNMRLERLRKYMNEKSIEIALIFEPDNQFYISGFKAITYSRP
                     IVTVVTQDKIELIVPGLEELHAKEVAKVDNVYVYYEIPEMKEHGISHKHYLDIILNKY
                     PKGTTVGIEKDIVSASFSEYITDKSFAIKDVGSKIFEMRYVKDAKEIEFLKIAGYLSD
                     IGIKGSLENVRVGMSELEFDVAGDNALLKYVSENYPDTYIGFANWTCSGIDRTAQPHL
                     DSNTRILQRGDIVIHSRQVWYENYRAENERTFIIGKPTERQKEVFKIAVEAQQAGLDT
                     IKAGIPARMVDEAARAVVAKYGLELYSNHRIGHGLGLSEHEEPYLRFDNELILEEGMV
                     FSMEPGIYIPGVGGFRHSDTAIVGKNGATIITNYPRSVEELILDI"
     gene            19469..20119
                     /locus_tag="JAM15_05835"
     CDS             19469..20119
                     /locus_tag="JAM15_05835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAT6797776.1"
                     /translation="MTNKELQKKRILMYFIEAAQNIMENEGIENITLRKVADMAGYNS
                     STLYKYFKNLDHLISFASIKYFKDYNLNISRCIENVNDEYKKYIIMWKLFCKHSFDNA
                     QAFYQVFFNLSSDELSYITKQYYDMFPEDLGIHDSDISLMITGESIKERNKILLNNLV
                     DTGYIPAKDLDIINDIIISFYQNLLFLKKNTGKNSGDDELTMKMISSIEYIIKHAK"
     gene            complement(20276..21295)
                     /locus_tag="JAM15_05840"
     CDS             complement(20276..21295)
                     /locus_tag="JAM15_05840"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HAT6797777.1"
                     /translation="MEKVCVLGTGSWGSALALGLAKKGNDVSMWTRKEEQAKKINRTK
                     ENTDYLPGVLFPNNITISTDIEKTIKDCKVIVLAVPSQAVRSTCQKIKPFIKEGQVIV
                     NVAKGLEKGTGLRLSQVCEEELPQNPYVILSGPSHAEEVARDIPTTVVVASKDLKIAQ
                     MIQDLFMSPKLRVYTNPDIVGVELGGALKNIIAFGAGICDGLGYGDNAKAALMTRGIS
                     EMSRLGIAMGANMSTFAGLSGIGDLIVTCTSMHSRNRRAGILIGKGMSLEDTLKEVKM
                     VVEGITATEVAHDVAEKLDIDMPITNAIYSVINKGSNPKEVGIELMMRSKKHEMEEVV
                     LGDDI"
     gene            complement(21326..21940)
                     /gene="plsY"
                     /locus_tag="JAM15_05845"
     CDS             complement(21326..21940)
                     /gene="plsY"
                     /locus_tag="JAM15_05845"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HAT6797778.1"
                     /translation="MEIFSYIIIAVVAYLLGNISTSYIVAKRIAGVDIRTQGSGNAGS
                     TNVLRTLGKRAGAMTFLGDVLKGVMAVLISEFAARLVGIDTLLAGYLAVICVVAGHNW
                     PAVLGFRGGKGVATSLGAMLAVNPVITLMCLAVFILVVAITKYVSLGSVVGIGCSPIF
                     MIMVKNKAGLIVALFLTASVIYNHRANIKRLLNGTERKIGQKKE"
     gene            complement(21975..23300)
                     /locus_tag="JAM15_05850"
     CDS             complement(21975..23300)
                     /locus_tag="JAM15_05850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HAT6797779.1"
                     /translation="MSISRPVVAVVGRPNVGKSTIFNKFAGKRISIVENTPGVTRDRI
                     FAEVEWLDKYFTLVDTGGIEPDSEDIILSQMRNQAMLAMDMSHVILFIVDGKAGITAA
                     DKEIAQLLRKTKKPVILVVNKIDSQSQFDNIYDFYELGFGTPFAVSGANSMGFGDLLD
                     EIVENFPAGLDTEYEEDIIRVAITGKPNAGKSSILNKILGEERVIVSPIAGTTRDAID
                     TYFEKNGQKFLLIDTAGLRRKSKIYETIEKYSVIRAMSAVDRADVVLIVIDALEGVTE
                     QDTKVAGIAHDEGKGCIFVINKWDLIEKDNKTMSNYTKDIKEKFPFMMYAPIVFVSAK
                     TNQRMNKILDTVEYVSNEHSKRISTSALNEVIGEAVMLNQPPSDKGRRLKIYYGTQTD
                     IRPPKITLFINDKDLTHFSYQRYLENKIRENFGFEGTSIKFEYRQKNKK"
     gene            complement(23328..24656)
                     /locus_tag="JAM15_05855"
     CDS             complement(23328..24656)
                     /locus_tag="JAM15_05855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF512 domain-containing protein"
                     /protein_id="HAT6797780.1"
                     /translation="MEVNVKKVNNIISKVYKDSIAEEIGIEVGDLLISVNEQPIHDII
                     EYRFLLSDEYLDVEIQKKDGEVYIYEIEKDYDEDLGVEFTNPIIDQAKSCRNKCMFCF
                     IDQLPEGMRETLYFKDDDSRLSFLQGNFVTLTNMSEEDINNIIKYRISPINISVHTTN
                     PELRQKMISNKFAGKLYGIMKRLADAHIEMNCQIVLCPGINDGKELDRTIKELAQLYP
                     YVNSVAIVPVGITKHRENLVELNIFNDKSASKTIEQIHQIQQKYLEKLGTRFAFLSDE
                     FYILSNSELPGYEEYEGFLQFEDGVGMIRKLKTEIEEYLNILPENILKREKKVSIATG
                     HSAYEFIQSMADAMMDKFKNLQVNVYEIKNKFFGETITVSGLLTAKDLKEQLEDKELG
                     EALYITRSMLKADEEIFLDNIELNQLEELMRIKIIPCLNEGKDFVDKILK"
     gene            complement(24894..25094)
                     /locus_tag="JAM15_05860"
     CDS             complement(24894..25094)
                     /locus_tag="JAM15_05860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797781.1"
                     /translation="MGMDIGLNEYTLAIVTLDKNMKNGGGCPIFYANDEKDLQNKALL
                     MSKCVGGMVHDMTNGTLIIVKH"
     gene            complement(25096..26028)
                     /locus_tag="JAM15_05865"
     CDS             complement(25096..26028)
                     /locus_tag="JAM15_05865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore envelope protein"
                     /protein_id="HAT6797782.1"
                     /translation="MDRVFFVAVIIGITSRIIMLNLDQKQYPTQPNVLLSQLILAFVA
                     SSLGALLVPALINRSYTSITFLSLAAEQFRQVRANRRNTLQNLEEVQLVKRGAAFIEE
                     IARTYEVRNYMCIVTSFLTIGLYYVILAETKISEGMSLVISSICGLVLAFILKKLLTR
                     KSIGDIADVMPAEISFVDESILKVGDLKGITNIGLKSDREVYINRGVGIQIIPKNKDY
                     ANAGILFDSGQRQAIVYNIYSRLGLYGDYGEPSFVPLPRRNKEDESIMIAYLPVDKNV
                     EKVMEAVKSCPILSSSKGKNLSLKNYKIGKKGSA"
     gene            complement(26073..27005)
                     /locus_tag="JAM15_05870"
     CDS             complement(26073..27005)
                     /locus_tag="JAM15_05870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797783.1"
                     /translation="MEESLLNANLFRHSFIVALVVGILCRGLVLRVTDKQYPSRPQDY
                     LEQIIISGLSASLGAIALPALIDKEFAALTFFAVAIQQFQGLAEQERITLKNIDNEEL
                     VPKGDAYVEEIASTYESRSYISLFSALVSSIVYIVFARKYDLSFFHCTILAIVSGAIV
                     GLIFRRFLRRNSIADIADIVPAKISFEGPILMVNDVIITNIGLESTREKYRNECLAIE
                     VIPRDLGAFGIVNDIGQRQAIIHNLFIHMGIDRDVDEVDIVAISKTNLEKSTVVIPYM
                     PILKDIDVMIDVVKSTPIIETSKGKQSDFSRKTL"
     gene            complement(27060..28349)
                     /locus_tag="JAM15_05875"
     CDS             complement(27060..28349)
                     /locus_tag="JAM15_05875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HAT6797784.1"
                     /translation="MEDLNSIYFFIVMLSIAIVILAVRYTITLRKYLKEFIYVSKKVS
                     NNEYHARLNISAKGELGELARNFNHMIKNMDKTLEEVQYKHLQLRSILKSISHGILAI
                     DVNGNILLINDEAKEMIKSEPNQLVEGHNINVVIKEEEILKQILQFIGSKDNETANIT
                     TKDDIVYKIKVDPVYLQNTNNVIIGSIVNIEDITKKVKLENMRSDFVANVSHELKTPL
                     TSISGFVETLKSNENIDVNTRNRFLEIIESESDRLKRLIDDILLLSFVENKDTLLMEN
                     VVVYDVFKEVYEITQHSASEKNIEVLYKCDDKSISILSNKDYIKQVFLNLVDNAIKYT
                     QDNGIVQVVVLKDEEKIVIKVIDNGVGIPKEDVERIFERFYRVDKARSRDVGGTGLGL
                     AITKHIVKSLNGCIKVKSELGIGSEFIVTILQKNFLK"
     gene            complement(28378..29070)
                     /locus_tag="JAM15_05880"
     CDS             complement(28378..29070)
                     /locus_tag="JAM15_05880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6797785.1"
                     /translation="MNTKVLVIDDEMHIVELLKFNLEVSNYEVSYSYDGFDGFIKAKE
                     IKPDLILLDWMLPNISGIEVLRKIRSDKDLKNIPVIMLTAKNMENDKVEGLEIGADDY
                     ITKPFSIKELLARISSVLRRYNLTSLGEENNILTTGNLKLDLSKHEVTKGSEKIELTL
                     KEFELLKLLIQNKGKVLSRNYLLDKIWGYEYYGETRTVDVHIRYLRKKIEDEDKSEKY
                     IETIRGVGYKID"
     gene            complement(29085..29843)
                     /gene="pgeF"
                     /locus_tag="JAM15_05885"
     CDS             complement(29085..29843)
                     /gene="pgeF"
                     /locus_tag="JAM15_05885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan editing factor PgeF"
                     /protein_id="HAT6797786.1"
                     /translation="MKDYINIKNVQDIKEYVNLSGNCEELDEKLNSVNLVITCKNIDA
                     KNREDMLKVCKECDLTFENITSNSQIHSDIVNIVNKDTIGKRRDGDALITNLEKVPLL
                     LFTADCVPISIIDAKNKAIGLAHAGWRGTFSNIGHKTIKLMSECYKTVPEDLVCIIGP
                     SIGPCCYEVSEDLVEKFNTILTNNDEKFYIIKEGSYYLDLWKINEYMLRCSGVKKENI
                     INLNLCTSCRADKFHSYRKHNKASERIGTVLQIK"
     gene            complement(29843..30304)
                     /gene="nrdR"
                     /locus_tag="JAM15_05890"
     CDS             complement(29843..30304)
                     /gene="nrdR"
                     /locus_tag="JAM15_05890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HAT6797787.1"
                     /translation="MQCPYCNYKESKVIDSRHTDLKSIRRRRECESCKKRFTTYEKIE
                     TTPLMVIKKDNSREYFDREKIKYGLLKACEKRPVSIEEIESIVVHIENEINKCFIEEI
                     ETKKIGEMVMDKLKELDEVAYVRFASVYRQFKDINTFVNELKSILIEKGDK"
     gene            complement(30326..30589)
                     /locus_tag="JAM15_05895"
     CDS             complement(30326..30589)
                     /locus_tag="JAM15_05895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HAT6797788.1"
                     /translation="MIRVSDIMEKEIINVKNGKRMGFIIDIDMDIHEGKVVSFTIFGD
                     GSRSFFSRGGDEEVIFWNDILKIGCDTIIVNIGSELSLDEFEI"
     gene            complement(30693..31466)
                     /gene="sigG"
                     /locus_tag="JAM15_05900"
     CDS             complement(30693..31466)
                     /gene="sigG"
                     /locus_tag="JAM15_05900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigG"
                     /protein_id="HAT6797789.1"
                     /translation="MQVNKVEICGVNTSELPVLKNKQMKELLLQIKNGDEEARQQFVR
                     GNLRLVLSVIKKFNNRGENIDDLFQIGCIGLIKAIDNFDLSQNVRFSTYAVPMIIGEI
                     RRYLRDNNPIRVSRSLKDIAYKALQVRERLIRTNSKEPTVSEIAKELELEVESVVMAL
                     DAIQDPISLFDPVYQDNGDAIFVMDQVQDKKDTDENWLQEISLKEAIKKLNSREKLVL
                     DLRFYKGRTQIEVADEIGISQAQVSRIEKNALKNMRKYV"
     gene            complement(31558..32280)
                     /gene="sigE"
                     /locus_tag="JAM15_05905"
     CDS             complement(31558..32280)
                     /gene="sigE"
                     /locus_tag="JAM15_05905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigE"
                     /protein_id="HAT6797790.1"
                     /translation="MLRLKERIISFITMLGIKLKIIKPKGIYYMGGANILPPPLKPEE
                     EMELLQKLETDESVKSILIERNLRLVVYISRKFENTGIDVEDLISIGTIGLIKAVNTF
                     KLNKNIKLATYASRCIENEILMYLRKNNKKKTEVSFDEPLNIDLDGNELLLSDVLGTE
                     NDEIYKIIEEEIDRDLLVMALDRLSDREKQIMELRFGLIDKGIEKTQKEVAGMLGISQ
                     SYISRLEKKIISRLQKEMKKFV"
     gene            complement(32305..33177)
                     /locus_tag="JAM15_05910"
     CDS             complement(32305..33177)
                     /locus_tag="JAM15_05910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-E processing peptidase SpoIIGA"
                     /protein_id="HAT6797791.1"
                     /translation="MFKGFKGGYMVYIEYYVIENLVINYIIISCTSILTKRYNPKKNK
                     LLGASLGSAYSVAYLYPSMNILFTVPFKIIIMSIITLISFRSKSKKDYVHVALVFYLV
                     NIFISGSTYFIIYFTGISHLKISFLIACTYVSCELLKYIYKDLKMLKYIKELTKTINI
                     NLLEKSFCCKALVDSGNLLKDPISQSDVIIVKSSVLEGFIPEKLLNINYEDIDMKKAQ
                     EIIGSLDDKTSGRVRIIPYKHAGSNKTSIIIGLKADYIEVDEQKIGNIILGISNFNDR
                     EYGAIMNPNILPGF"
     gene            complement(33468..34742)
                     /locus_tag="JAM15_05915"
     CDS             complement(33468..34742)
                     /locus_tag="JAM15_05915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAT6797792.1"
                     /translation="MIKLKKVLSLVMVGILSVSILAGCSKKEDSKGKEGKEKLVVWSA
                     PLTDHDADAWKPIFEKFEKENNCEIEFQIVPWDNYAEKYATAISAGEGPDIGYMYAEM
                     FPQFIEMGAVEDLTPYLEKSGTSDNYLYLDDAKMMGGIYGLPIEAANPGVLYYNKDIL
                     EKLGEKPPKTWDDFKRICEKATKDTDGDGKIDQWGLAQGWGSKVFGSLNWNWYPYLWQ
                     AGGDIYNDDLKSVKFNNAEGLKAANFINDMKKYIPEDALSKDSNEMIESVFGPGKAAF
                     TIMLSSAATSTFDKSFPDLNWGYVTSLEDKTVGSFASVDDLTLMSACKNKELGFKLLE
                     YMLSKESMEAFHKEIPRAPVAKGEKYQGDPRFEEMVTRDKHMYRPLTVGPHGVEIYEY
                     LWKQLQMMIAGDITPEQALNESAKYANGLLAQ"
     gene            complement(35026..36183)
                     /gene="ftsZ"
                     /locus_tag="JAM15_05920"
     CDS             complement(35026..36183)
                     /gene="ftsZ"
                     /locus_tag="JAM15_05920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HAT6797793.1"
                     /translation="MLNFDVELEECAQIKVIGVGGGGNNAVNRMVEAQLKGVEFISVN
                     TDKQALYTSKAEYKVQIGEKLTRGLGAGANPEVGKRAAEESKDEIVKLLQGADMVFVT
                     AGMGGGTGTGAAPVVAGLAKEMGILTVGVVTKPFAFEGKIRMKNAEGGIAELKSKVDT
                     LITIPNDRLLQIVQKNTSMLDAFAVADDVLKQGIQSISDLIAVEGLINLDFADVTTIM
                     KDKGLAHMGIGSASGETRAIDAARQAIQSPLLETSIQGAKGVLLNVTGGPNLGLFEVN
                     EASTLVMESCDPEANVIFGASIKEDLGDEIMITVIATGFEGLQNGALDLDTKPKSSIR
                     SSLNTTVKQAVKEIEEEVIAEEKIEPPKKASIIEEDDDESMEIPTFLRRRR"
     gene            complement(36373..36726)
                     /locus_tag="JAM15_05925"
     CDS             complement(36373..36726)
                     /locus_tag="JAM15_05925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small basic family protein"
                     /protein_id="HAT6797794.1"
                     /translation="MLWVLGGLAFGVVVGYYIPFTYSMDYSIYMSVAILAIMDSIFGA
                     IKSNFEDNYDNVIFITGFIGNAILAILLTYIGEKLGVSLYYVAVLVFGMRLFNNLSII
                     RRYIISNIMNKKRKN"
     gene            complement(36825..37499)
                     /locus_tag="JAM15_05930"
     CDS             complement(36825..37499)
                     /locus_tag="JAM15_05930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HAT6797795.1"
                     /translation="MKKKIVILGAFILGIFISTYIKSLDPNRVYITLGQTESIESEVE
                     NTKKEIKNLKETLKNNKKTLNEYKEAKKNGNESIQTLMQKELEEVKELSGYSTVTGPG
                     ITITMRDSERELKDGQNPNDLIIHDIDILRVLNDLKKAGARAISINGERVLATSKIKC
                     SGATITVNDTTYGQPFIIKAIGDIDLLSAAINSPESYAKSLKDIYGINIKVQENNGNK
                     VNLFAK"
     gene            complement(37504..38202)
                     /locus_tag="JAM15_05935"
     CDS             complement(37504..38202)
                     /locus_tag="JAM15_05935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HAT6797796.1"
                     /translation="MKKRFINKSIIIGSVVLGVLVSLQLKIINIENRGMTTFKRGEQL
                     TEELKSLKKEKENLQSEVNSVKKDIETYRGKNNKGEQDILKSEIEKYETLAGYTDVEG
                     TGIKIEINSTKDLGNSDKNDSILYNYDLLLSMINKLNSAQASAISINDQRIVFNTYMY
                     LKEDKLYMNDTVIKEPIIIKAIGDSDTLASALNIKYGIVWEIETYYNAKVKVTKEDNI
                     EINGHSDINKAEGK"
     gene            complement(38225..38965)
                     /locus_tag="JAM15_05940"
     CDS             complement(38225..38965)
                     /locus_tag="JAM15_05940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HAT6797797.1"
                     /translation="MKKRRKLNTNNVMIVLVFILMLSFCICIIVKSDLFDVKKIDVIG
                     NKRVTKSNIMKELNINLNENIFAYNFKDMKNKLIKNPYIENVEIKRKLPNKIIISLKE
                     KEIFAVLKDEDNYCYIDKKGNLLEELRGSNESKKDLIVDVDYSVDDNKSIKFKNYKTK
                     ENVFKTLNYLKEEGIYRKINYVNLKKESNIEMLTRSNIKILLSNDDNLDYNISRVSKI
                     LIDLQNKNTNGGTINLNYGKLAVYSPEG"
     gene            complement(39235..40461)
                     /gene="murG"
                     /locus_tag="JAM15_05945"
     CDS             complement(39235..40461)
                     /gene="murG"
                     /locus_tag="JAM15_05945"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HAT6797798.1"
                     /translation="MKVLLSGGGTGGHVYPAIAIANKIRDEHPDAEIIFVGTEKGIES
                     EIVPKYGFELKTVTVQGFKRKIDFDNVKRVFKLFKGLEQSRKIVKKFKPDIVIGTGGY
                     VSGPVLFNASMGKIPAIIHEQNSFPGVTNKILSKTVTKVLTSFEDSHKRFPEAAEDKL
                     VFTGNPVRKEILLSRKNIARKNLSISDEKRMVLCYGGSGGSRKINDAMRLVIKNMVNE
                     DIAFIFATGKSYYDEFMGSISDINLKPYQKVVPYLEDMANALAASDLVIGSAGAISLA
                     EITALGKPSIIIPKAYTAENHQEYNAKSIEKQGAGIAILEKNLTPESLNTAVFKLLGD
                     RELLVDMANASKTIGKPEAIDLIYDEIMKVYNSTQKSTSKKTKKEKVIKEVKEIKKET
                     TPSIEGQAKVIGIKKR"
     gene            complement(40479..41609)
                     /gene="spoVE"
                     /locus_tag="JAM15_05950"
     CDS             complement(40479..41609)
                     /gene="spoVE"
                     /locus_tag="JAM15_05950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein E"
                     /protein_id="HAT6797799.1"
                     /translation="MPKENLKKQIDIRMKTEFDGVVFYTTMLLVFVGIVMVFSASFIQ
                     SSFKHNDAYYFLKKNVIYAVLGFIVMIITSRIDYSFWKKNATAIGAIAVVLLLLVLTP
                     LGIEANGAKRWLGIGALTFQPAEIAKFATIILTAKLIEKNYDKIKSLTKGVVPLLVVP
                     GIFFALIILQPNLSTAGTVILVTFVMIFVAGMDMKIVFAMIGSGAALFAALVIAEPYR
                     LSRVTSFLDPFQDPLGKGYQVIQGLYALGSGGLFGLGLGKSKQKYFYIPEPQNDFIFA
                     IIGEELGLIGCIIVIMLFVVLVYRCVRIALKTSNVFACMVVIGIGAQIGIQAALNIAV
                     ATSSMPATGVALPFISYGGTSLTIFMGAVGIVLNISKHVKIN"
     gene            complement(41661..43016)
                     /locus_tag="JAM15_05955"
     CDS             complement(41661..43016)
                     /locus_tag="JAM15_05955"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HAT6797800.1"
                     /translation="MDLKGKKVLLVGLAKTGISTIKHLDKLGASIIVNDIKDENKLRN
                     ILDELKSINDIKYILGHHPEDVDDIDMVVVSPGVPLDLPFILKLKNSGKYIIGEVELA
                     FKLSNNPIFIGITGTNGKTTTTSLVGEIFSRAKRDTYVVGNIGNPVIDTIETSSEESV
                     LVTELSSFQLESIDEFRPKVSAILNITEDHLNRHHTMEKYIEAKANIFMNQTVEDFCV
                     LNYDDEVVKSLADKCNAKVIYFSRTKKVNGGVYLENNDIIIDIDDKIKFLNKDDVSLP
                     GGHNLENCMAAIAIAYVCKIDLEVIKDVLMTFKGVEHRQEFVRNLDNVIYVNDSKGTN
                     PDSTIKAIQSYDRPIILIAGGMDKGSNFDELLETAKSYVKSLVLLGETASNIENCAKN
                     KGFNDIHIVKDMEEAVKTSYEISKSGDIVLLSPACASWDMYESFEVRGKDFKDNVNNL
                     K"
     gene            complement(43035..44003)
                     /locus_tag="JAM15_05960"
     CDS             complement(43035..44003)
                     /locus_tag="JAM15_05960"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HAT6797801.1"
                     /translation="MMLGITELTYTALIAFLIVIIIGPIFIPMLRKFKFGQTVRDDGP
                     QTHLAKNGTPTMGGIIMIVAILITGLTRVKVSHDMAVGLICIAGFGFIGFLDDFIKIK
                     LKRSLGLKAYQKIILQVALSFYVAFYQYTSSSSASQLMIPFTDFVINVGILYIPIMMF
                     IIVAIVNAVNLTDGLDGLASGVTLIVSVFFMLFASSIAGNTEVAVLAAATVGACLGFL
                     GFNSYPARVFMGDTGSMALGGAVVAFSVLTNSVLIIPIIGGIYFAEALSVLIQVGYFK
                     ATRKRFFKMAPIHHHFEQCGWPETRVVFIFWIITVVLAWISIIAVF"
     gene            complement(44044..45417)
                     /locus_tag="JAM15_05965"
     CDS             complement(44044..45417)
                     /locus_tag="JAM15_05965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HAT6797802.1"
                     /translation="MECLTIKELVLATNGKLIYGDYNDCVSDIVIDSREASAQNAFVA
                     IVGENLDGHTFMKPAYDSGCKTFIKNESNGIKLESSDINLIEVKDTSLALGDISKYYK
                     EKFDIPFIGVTGSVGKTTTRDMIYSAISAKLNILKNEKNLNNHFGVPLTLFNLNKEHE
                     CAVIEMGMSGFNEIKYLVDIVNPKIAVISNIGLSHVEKLGSQEGILKAKMEITSNFDE
                     TNTLIVNGDDKFLSTLKEKEHVYKLKTFGFNKNNDIYCESYTMEEDSLTFICVINGKK
                     EEIFIPTIGEHNIYNAMSAILVGLCLNISLDYIKKGLKNFKGTKMRLDIIKNEKLTII
                     NDSYNASPDSMDAALKILGRYKGRRVAILGDILEMGEISEYGHRLVGKSSMNNTDIII
                     TIGENSVFIGEEAKQLGFNSANIYHFENREDVFNKLNELVKTGDTILVKGSRGMRLEK
                     IVEYLNK"
     gene            complement(45584..47563)
                     /locus_tag="JAM15_05970"
     CDS             complement(45584..47563)
                     /locus_tag="JAM15_05970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein D"
                     /protein_id="HAT6797803.1"
                     /translation="MRKVKRISKKRLVLVLILACALFFCLVIRTGYLQLMKGNWLSTK
                     ALEQQTRDIPIEPKRGTIYDRNMKELAVSVTKYTVWCKPVEVEDKKEAAEKVAEILDE
                     DYKDIYALISKKNMALVKVKRWIDDDKASQIRDAKLSGIWVAEDNQRYYPYGNFAPYV
                     LGHTSSDATGISGVEMQYDKKLKGKPGKLIVSTDASGREIPQGMEKYYEPVQGNGLVL
                     SIDEVIQHYTEKAVQKAYELNNAKKVTAIAMNPKTGDILALASKPDYDPNDSRTPIYP
                     YYQEELEKYNDKDKIKGYYQMWRNPAVSDTYEPGSTFKLITSSSALEEGVIKDGEKFT
                     CTGSVTVGGRKIKCWRHYRPHGTQEFKQAVQNSCNPVFVELGSRLGVGKMYDYIESFG
                     LMDKTGIDLPGEAKGILYNEKNVGPVELATISFGQSISVTPIQLITAISSIANGGDLM
                     QPRVVKSYTDNKGNITETVKPKKVRSVISKETSKKMLEIAESVVTEGGGKIAYIPGYR
                     LGGKTGTAQKVIDGKYAPGKYICSFVGIAPCDDPQIVVLAIVDEPTGVSAFGSTTAGP
                     IVKEIMNDSLKYLGVKPVYKEEEKAEYEKKQVKVPDVRNLKIGDAVKALEDAKLKPDL
                     DADIELPEDTKVKDIFPKPGVKVNEDSSITLYFEN"
     gene            complement(47575..47922)
                     /locus_tag="JAM15_05975"
     CDS             complement(47575..47922)
                     /locus_tag="JAM15_05975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797804.1"
                     /translation="MKKNYKIHNLNEYKNKKKNNYKKRNKKKIGAKCILLIATFSVII
                     LNLCGYSKISEMKYDIYYLQKDLRKKEIVLEELKAKETEKTSIKEIELKAKELLNMDY
                     PKDGQIKYIDVDN"
     gene            complement(48408..49343)
                     /gene="rsmH"
                     /locus_tag="JAM15_05980"
     CDS             complement(48408..49343)
                     /gene="rsmH"
                     /locus_tag="JAM15_05980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010077296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HAT6797805.1"
                     /translation="MEFHHVSVLLNECIENLNIKPDGVYVDCTMGGAGHSKEIVKKLS
                     DKGLFIGFDQDKNAISTAKERLSEYESRVKFVHSNFENIKEELEKIGVYKIDGVLADL
                     GVSSHQLDEADRGFSYMQDAPLDMRMDVRCEFSAYDVVNTYTEDELTKIIKDYGEDNW
                     AKRIAKFIVEERANKPIETTGELVDIIKKAIPKKARIDGPHPAKRTFQAIRIEVNNEL
                     GVITKMINDASSIMNKGGRICIITFHSLEDRIVKNAFKHLASDCICPQHLPICQCDKE
                     SEVKIITRKPILPSEEEIEVNPRSRSAKLRVAEKI"
     gene            complement(49373..50119)
                     /locus_tag="JAM15_05985"
     CDS             complement(49373..50119)
                     /locus_tag="JAM15_05985"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HAT6797806.1"
                     /translation="MDRVAFTLFGIDIMWYGILMACGMILGTLIAIKEAKRVGIKEDD
                     VLNIAIIAIPVGLICARIYYVVFNWSYYAQNMSQIFNFRGGGLAIHGGLIGGILAGYI
                     YTKIKNINFLKMADTVILGMPLAQAIGRWGNFINGEAHGGATNLPWGIMVDGVKVHPT
                     FLYESIWDFGIFIVLLLFRKNKKYEGQVIVTYITLYSIGRFFIEGLRTDSLMLGPLRM
                     AQVISLIGVIGGIIAHVYLSKKNKNNISEE"
     gene            complement(50516..51802)
                     /locus_tag="JAM15_05990"
     CDS             complement(50516..51802)
                     /locus_tag="JAM15_05990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HAT6797807.1"
                     /translation="MEKIVNDILKEEVYYEKLQNGLDVYFMPKRGFMKKYAILATNYG
                     SNDLEFVPIGEDKKIRVNEGIAHFLEHKMFEQPDGGDAFDKFSKLGVNANAFTNFTMT
                     AYLFSATENFYESLEHLIDYVQTPYFTDENVEKEKGIIAQEIKMYNDDPDWNVYFNCL
                     KAMYVNYPARIDIAGTVDSIYKITKEELYKCYNTFYNPGNMALFVVGDLDVEKVIDVT
                     KKSNNYKVDKLSKSIERFYPEEPESVKEKEVIEKFPISMPMFNIGFKDSNVGLKGKEL
                     LRKEIVTDILVGMLFKKGSKLYEDLYMQGLINENFGAGFSSQVDYAFSIIAGDSKEPK
                     KVKEIILDYIEKSKKEGLSKEEFERTKKKKIGSFIKCFDSINFIGNSFISYVFKDINL
                     LDYLDVIKDITFEEVEERLKEHFKEEYCVISIVEPK"
     gene            complement(51817..53082)
                     /locus_tag="JAM15_05995"
     CDS             complement(51817..53082)
                     /locus_tag="JAM15_05995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HAT6797808.1"
                     /translation="MVNTKKIINLGNNINLTLIKTEKFKSNLISLYVQRLLDEKETTK
                     NALIPSIIASGSAKYPSARAISNKLDDLYGSSMGADAVKRGERQVLSFKVINISEKYL
                     DESIFEEVVEFFNEVINNTLVVDGGFKEEYLNIEKENLREKIQSIINDKKEYAQDKCI
                     EAMCKGERYSVSEFGYEDEIDSITSRELYEHYKNILKTSPIDIVVEGNFDEDKVVDII
                     SKNLKFEREEIINIPRADFIKNVDEVKVIDEQMEITQGKLVMGYRANVDYADIDKYYA
                     LVVGSNVLGGGPHSKLFVNVREKESLCYYIFSSIEKYKSIMFISSGIETKDYDKAVEL
                     IKKQVESVKAGDISDEELENSKLALVNSMKSITDNIGGMSDFVFSQSMAKTNSEVQDI
                     ISSIEKVTKKDIVEAIKNIELDTVYFLRN"
     gene            53398..54495
                     /gene="ychF"
                     /locus_tag="JAM15_06000"
     CDS             53398..54495
                     /gene="ychF"
                     /locus_tag="JAM15_06000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002844781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HAT6797809.1"
                     /translation="MKLGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGVVSV
                     PDERLNKLQELYNSEKIVPTAIEFCDIAGLVRGASKGEGLGNKFLSHIREVDAIVHVV
                     RCFEDENVVHVDGSVDPLRDIETINLELIFSDIEILERRINKTQKAAKADKTLGSELD
                     LLKSIMSTLEESKCVRTMEFTEDEQTFVNSLDLLTSKPVIYASNVSEDDLADNGENNK
                     YVQQVKAFAETEDAEVVVVCAQIEAEISELDSAEEKKEFLETLGLEQSGLDKLIKSSY
                     ALLGLISFLTAGPKEVRAWTIKVGSKAPQAGGKIHSDIERGFIRAETISFNDLVEHGT
                     MAAAKEKGLVKLEGKEYIVKDGDVILFRFNV"
BASE COUNT        16902 a         9995 c         5793 g        21855 t
ORIGIN      
        1 gtttccctat atgctgacta ttttagctac taactcatga ctaaagtcac gagtgtgcgt
       61 agctattttt taatcaatac ttaacttttt gttttcacca tacatcaaaa cgcacccctt
      121 tgcataataa ataaaccacc ctgcagaaca cacgataaat ttataaataa atttatcaga
      181 agtagcttac taaaaatatt attcatcctc acttaaacgt ttattcatta atattctatc
      241 acatgacata aataatttat atgatttata tagatttatt tattgtaaat tttggaatat
      301 taaaacattt tattgaatag ataattatat tacataaaaa atccctatag aaatctataa
      361 actaatttct atagggattt tggttaacta actattcttt ttattttttt ataactttta
      421 tacctgtcat atggtcattt aagttttgtt cctctaaaga tttatcatct actctgttta
      481 tttctaaagc taaagtttca gacttgatat attcattaaa atggtcaaca gccttagcaa
      541 tttcatcatc accacagtat tctattacta tattatctaa tacttcaaag ttattagatt
      601 ttcttaattg ctgtacttta gatataaatt ctctagcata accttcatta atcaactctt
      661 cagttagctt agtatctagt ataacaaaaa gattgttttc aacagataca ttaaatcctt
      721 ccttagcagt tatacctatt aatactaaat ccttattaaa ttcaaaagct tcgccatcta
      781 aatcaactgt taaagtctca cctttttcaa gtttattagc agtttcatga gcatttaatt
      841 tacttaatgc tccaacgaat aaattcatct tagaacctaa taatggccct gcttccttaa
      901 agtttggttt taaactaaag ttcatatact catctaaatc cttagcaaat attacctctt
      961 taacattaag ctcttctttt attaaatcaa ctacatcact tattgtatct tcaaacttac
     1021 catctactaa cactttttgt aatggttgac gaacttttat tctttctact tctcttgaag
     1081 ctctacctaa agtaactaag tttttagcta aatccatttt ttcttctaat ttagtatcta
     1141 ctaactcttc attacattta ggatattcag ctaaatgaac agatacttct cctgttaagt
     1201 ttctatacat ttcttctgac atatatggtg caaatggagc tatagctcta caaagaccat
     1261 gtaacaattc ataagttgta ttgtacactg cttttttatc ttctgttaat tcagttgccc
     1321 agaatcttct tcttgaacgt cttatatacc agttagataa atcatcattt ataaaatctt
     1381 gtatcatcct taaagtttta tttaactcaa atatagctaa attttcttct acatctttca
     1441 ttaaattatt gaacttagat aatatccatc tatcaagttc tggtctatct ttatattcta
     1501 caaaaaattc agttggattt atatcatctg tgtttgcata taaagtaaag aagttatata
     1561 cattcttcat agtacctata aatttacttt ggatttcttt taatccatcc atatcaaatt
     1621 tagttggagt ccatggtgga gaaacatata gtaaatacca tcttaatgca tctgctccat
     1681 attggtcgaa caattccatt ggatttactg tatttcctct tgatttactc attttcttac
     1741 catctttatc aagtacaagg tctggaacta aaacactctt atatggtgct tttcctaata
     1801 caaatgttga tactgcaagt aatgagtaga accaacctct agtctggtct ataccttctg
     1861 atatatagtc agctgggaac aattggtcaa aattttcctt attttcaaat ggatagtggt
     1921 gttgagcaaa tggcatagcc ccactatcaa accaacagtc tataacctct gttactcttg
     1981 tcattggttt tccacatttt tcacatttta agtgtatatc atctacatat ggtctatgaa
     2041 gttcaactgt ttctggattt acatcttcta tagctttttc agctaattca gctcttgaac
     2101 caactgaatc tgtatgacca cattcacatc tccatatagg aagtggagtt ccccaatatc
     2161 tagttcttga tattgcccag tcatttagat tttctaacca gtttccaaat ctcttctctc
     2221 ctacaaaact tgggaaccat tttacaccat tattattttc tattaattta tctttaagtt
     2281 tagtcatctc tatataccag cttggttttg catagtatac taatggagtt tgacatctcc
     2341 agcagtgtgg ataattatga actacttttt ctttgctata taatttattt tcagaagcta
     2401 gccattttat tatttcaaca tctagcccat cttccattac aaatctacct tcccaaggag
     2461 tagatgtaaa tttaccagtt tcatctactg gttgaataac tggtaaatca tatcttttac
     2521 ctgtgttgta gtcatcttca ccaaatgctg gtgctgtatg aactatacca gttccatctt
     2581 cagtagttac ataatctcct actgtaataa aaaatgcttt tttgtcaact tctacaaaag
     2641 gcattaattg ttcatattct aaaccttcta ggtctttacc tttcatttct tctaaaactt
     2701 cataatcttc acctagtact ttatcagcta aaggtttaga tacataatat acctcatcac
     2761 cttttttaac ttttaaataa tctacatcag catttactgt taatgaaaca tttgatggta
     2821 aagtccatgg agttgttgtc catgctaaga agtattcatc agcatctttt ttcttaaatt
     2881 tagctataac tgtattagtt tttacttctt tatatccttg tgcaacctca tgactagcaa
     2941 gaccagttcc acatcttggg caataaggaa gtattttatg cccttcatat atatatcctt
     3001 ctttgttgaa tttgtttagt atccaccata cagactctat atagttatta tctaaagtta
     3061 tatatggatt atctaaatca acttcataag ccattctctc agtcattatt ctccattgtt
     3121 tttcaaatga gaaaactgac tctctacatt tttggttaaa ttcagctatt ccatattctt
     3181 ctatttgttg cttgctagta agacctaact ctttctctac ttgtatttca actggtaatc
     3241 catgtgtatc ccaaccagct tttctcttta cttgataacc agacattgtt ttatatctac
     3301 aaactgaatc tttaagcgtt ctagataaaa catggtgtac tccaggattt ccattagctg
     3361 ttggaggtcc ttcatagaat acgaaacttg ggtcatcttt ccctttttct aaagtttttt
     3421 caagtatatt tatgtctttc caataatcaa aaacttgtgc ttctgcttgt tttacagaac
     3481 tgtctaccaa tggcttaaat ttcgccatgt aaatcaccct ttcctactaa atattataat
     3541 tccaaaattt tttattcttt cacataaatt taaatactaa aaaactcgcc ccctttaaac
     3601 caaagggacg agttataaat cgcgttacca ccctaattct atatgtaaac taaatactag
     3661 ctacatataa cactctaata gtataacggt actaaccggc acagcttagt agaatttaat
     3721 cgttcagcct gcagctcaag agtgattttt atctttataa attcattggt tctcagcata
     3781 cccaattctc tgtaaaatta tctaaagata aatgtctcta tcaacgcttt taaaaattta
     3841 tctgtgttta tatgaaattt tataacaaat aatttgaata gtcaatatat ttttgaaaaa
     3901 tataataatt tctatttttc ttacattttt atcctatttt taatctttgt tatagatttc
     3961 tcaaactcac acagttattc tacataaaaa ataaacaaat tacaagctta ttctaaagtt
     4021 gtagcagctt catcattact ataattatac actgttgttc cttcaaatgc atttacacat
     4081 ttttcatcta catcataaaa aatctcatca acacttctta tttcatcttc taacagtgat
     4141 ttaaatttat ttctaaatat cttaaattct ttgactaaag catcatactc ttttcttatc
     4201 tctatgacac ggttattagc ttgttctata atttgtctag cttttaaatc agcttcttca
     4261 acaattatct tagccttttt attagccgcg ctacaagtgt cttctgctgc actttgagca
     4321 gttattaaag tagcttttag tgtttcttca atattttcat acttgtttac ttggtcttga
     4381 tataacccta atttttcttt aagagctgta ttttccctac atagagattc ataatcttcc
     4441 ttgatgatat ctaaaaattc atcaacctct tcatctctat accctcttaa acctttttta
     4501 aactctttat tttctatctc aattggagtt agcattacat ttcctcccag ctataattta
     4561 aattagtcct tatacaatta atcttgcttg aacttttatt tttccttttt tggtaatatc
     4621 tcctatttgt gttaccttag ctcttccttt gcctctaata gaaatcaaat catcattttt
     4681 tactatttta gaagttgaag ttatcttttc ataattgaca tggacttttt ctccatttat
     4741 gtattttgca ctatcttgtc tagatatatt gtaaatacca cttatcacac aatctaacct
     4801 atctgaagat actgtaaatg atacttcttt atattttgaa gaactattaa caatattttc
     4861 tctggaaatt tcctttacaa ttacattatt tcttgaaacc ttttctaagt ttacaattat
     4921 aaaatcgcaa atatcactac ttacaactac ttgacaaaag ctatcatgta taattatatc
     4981 tccaattttt tctcttttta tacctagacc cagtattgac cctaagtaat ctttatgaga
     5041 tatattttta aacttgaaat tcccttctat ttgtaaaaat ctaagagtat cttctatatc
     5101 ttcatattcc atgtaaaatg gataaataaa tacagtgctt ctttcagctt gttcataacc
     5161 tccatccaca ctgtatttta tttcatttgt agaatttaat attgctacag catttttcac
     5221 ttcatatgga ttaagaaact ccgtagactt aacatcatag ttttttatac aactattagc
     5281 cttgtctatc actttaaaca ttttattttt caagtctata tcctttatgt gatttgttag
     5341 ttttaattta tccatcctat caccttagaa tataaccaat actaattgtc ttaggaacat
     5401 caataatact attgcaatta aaggagaaaa atctataggt ccatttgtat atttatacat
     5461 tatagacctt attggccctt ctattggctc tgtaagattt tccaaaatat taaaaatttt
     5521 actttgtctt ccatttggaa accaagtcat caagcttttt ataactatca tccatgctat
     5581 tatatctaaa agataataaa gtgcaattct tattgttccc atatattaac cgccttttta
     5641 ctatttattt tgccaaggga agaatgcttt actttctaat tcttttttca tatttgcatc
     5701 tatatccaca ttattaggag ctagtataaa tattgattta gaaacctttt gtatacttcc
     5761 atctaagaca taaactgccc cattcataaa gttaaatata gatttacgaa cttcagaatt
     5821 agtcaatcct tccaaattca ctataactgc ccttctttgt tttagatggt ctgctatagt
     5881 tgcagcttca tcataaacct taggttcaac tattacaact ttcatttggc tagttgtatg
     5941 taaatttaca attttatttg cttttgcagt actaaagcca ctgttcattt cttcttcttg
     6001 aactatatcg tccatgccac tttcatattc atcttcaatg taatcttctt cttcatcaac
     6061 tatccaattc ttaaatttag atattattcc atttgacatt attaacttcc tccttaaaat
     6121 ttattcaaat ttgagtaatt attttttatt gtagtttctt tctccaaaga ttgatgttcc
     6181 aactctaaca atggtagccc cttcctctat agcaatttca taatcgtgac tcattcccat
     6241 tgacaaaaca tccatcccta cattagggat gtttagttct tttatttgtt ttgataaatc
     6301 tttaagacct ttaaatacac ctcttatctc atcttcatct tctataaaag gtgccattgt
     6361 cattagaccc tttattttta tatttttata tttttctgac acttctttga caaaatctac
     6421 aacttcttct ctatcaagtc catgcttaga ctcttcttta gatatattca cttgtactaa
     6481 gcaatctatt tctctgttta tttgttctgc acgtttttga atttcttcgc ataatgcaat
     6541 tctatctaaa gagtgtatca tacaaacttt atcgattatg tacttaactt tattggtttg
     6601 caaagttcct atcaggtgcc agtttaattt gtcacctata atatcatact ttctagctaa
     6661 ttcttggggt ttattttcac caacagaagt gattccttcc ctcattgcct cattaactaa
     6721 gtctacatca acagtctttg tgactgccaa aagggtaatc tctttgctgt ctctatctac
     6781 tttttttgca gctttatcaa ttttgtttct tatctcagac aaattatctt taatagaacc
     6841 cattattatc acctacttta tccttatatt tgtgtttata ctgttaggtc ttaaaattat
     6901 tttgtcatat agattaacac ttgtaactcc atttatgtca tttttataat aatccacaaa
     6961 tacagaagat tcattctcat aagttattcc ttctaatatg acaaatttta cactttgtga
     7021 ttgttcatca attacatata caccacgttt attgtctttt gtttttatag aagttttagg
     7081 tatttttaaa cattccatct gattatatat tatatcaaat tcttcgacac ttgtatcctg
     7141 atttgcaaca atttggttac ttatttttaa ttttaccatt attttattat tattttcata
     7201 tattttgtaa acttttgcat ctaatttttg ctcatgatat tcaattatta cattttgatt
     7261 tttttcaaag ttattagaat cttctttact gatgtatgta gatagataat tactttggtc
     7321 attggcatct ttttctatag ttccttttac atgaatcttt gcattaactt tttcattttt
     7381 taacaccaac gtatctacat ttttgctaat tatcattact aatatattaa atactaaata
     7441 tataagaata ccaagtatca ctaatctggt atattttacc tttttcaaag actctccccc
     7501 tataaaatta ctttcattat aagtacttct tctaaaaaat gtttattcct tttttataag
     7561 ctaatatttt acgttctaat aattattttt tccatattaa atttattttt tatcaatctt
     7621 cctatacaag actgcattat ttatatataa ttgtattata aagtataagt ttaatttaca
     7681 ttttatacat taagcttact ttatatgttt ttatagttat ttttattttt agatgcaata
     7741 taaaaccaat taagatttaa aataactttt gttatgttga catttattta ggtaatcatt
     7801 tacgaatcgg gataacgtta tcataacaaa agtttatgtc ctaaaaaaaa tacaaggagg
     7861 attttcttat gtcagaaatt ttattaggaa caggtttact tttattggtt ctatgttgtt
     7921 tcacaatttt tagttacaag gccccatatg gtatgaaggc tatgggagct ctagcaaacg
     7981 ctgcatgtgc tactttctta gtagaggcat tcaacctttc tttacttggt gatgttttag
     8041 gtatggaatt ttttagaagt gttggagctg ctaatggtag tcttggtgga gttgctgctg
     8101 ctatacttgt gcctttagcc ttaggtgtat ctccagttta tgcagtttta ataggattat
     8161 cttgtttaga tttttctata ttatctggat tcgttgctgg atactttgtt tctttcttaa
     8221 ttaagtttat agagaaaaaa gtgccacctg gagtggattt agtggttgta attcttctat
     8281 gtgcaccgct atctcgtctt atagcatcaa atgtagaccc attagttaat agtacactac
     8341 tacaaattgg acaagttttg atagaagcta ccaacattag ccctataata atgggaatta
     8401 tactaggagg cctaataaca gtagttggaa cgtctccact tagttcaatg gctcttacat
     8461 ctataattgg tcttactggt cttcctatgg caataggagc attaggtgct tttggttcag
     8521 cttttatgaa ctcaacacta tttgcaaaat tgaaattagg ttctaaaaaa gatattatat
     8581 ctgttgctat tgaaccatta acccaatcag acataatttc agctaatcca atacctatat
     8641 attctactaa tttctttgga ggagcctttt ctggtatcat tgtagccttg atgggtcttg
     8701 taaacatgac accaggtaca gctacacctg tggctggttt tgctataatg tttgcttata
     8761 atccagttca acaagttctt ataacagctg gtttatgtgc tttattcaat gtaattgcag
     8821 gatttttagg ttcaaaaata ttcagtacct ttaaagttct tactgctggt gaaatacgtg
     8881 gtactgatgt agaagaagaa attgcttaaa aaacaataag atttataaat ttatatctca
     8941 agtagtagag ttttatattg taggcaattt tattaattgc aaacgtttta ttttttattt
     9001 atgtttatga ttattatgtg tgttgaatat ttagataaat ttttatttat tatttttgtt
     9061 tagtttttta tttggttgat atattaggaa taaaaattag tatagtttat tattagttag
     9121 atagcataac tttttagata cataaaaaat tttatattaa ttagatatta ttaaaataaa
     9181 agcgatacat gaatttttaa atgtccatgt atcgctttat ttttgccata atcttaacaa
     9241 ctgattttta aagtttatta tcttaacgaa gttcattatc ttatataata tttaaatgca
     9301 tagacttctt taatttaacc atccaaatat ttaattaaat attattatat gtaatataac
     9361 taatttttaa atgaatgtat aggagctgga atccttcctc ctctttgagt aaataattca
     9421 gatgaatttg tacttatagg cattactggt gctcgtccta aaagtcctcc aaattctacc
     9481 atatcaccta catcacatcc tggggctggt ataattctaa cggctgtagt cttattatta
     9541 atcataccta ttgctgcctc atcagctatc atagctccaa gcgtacctgc tgtagtattt
     9601 cctggcacag ctatcatatc aagacctaca gaacaaatag cagtcattgc ttcaagctta
     9661 tctatactta aagcaccttt aataacagca tcaatcatac ctgcatcttc agatactggt
     9721 ataaacgctc cactaagtcc tccaacatgt gaacatgcca ttactccacc ttttttaaca
     9781 gcatcattta aaagtgctaa tgctgctgta gtcccatgag taccaacaac ttcaagaccc
     9841 atttcctcta atatatttgc tactgaatca ccaatagcag gtgtaggagc tagtgataag
     9901 tctattatcc caaatggaac atccaatcta ctagaagctt cctttgccac aagttgtcca
     9961 actcttgtaa ttttaaatgc agtcttttta actgtttctg aaacaacatc aaaaggctct
    10021 ccctttactt tctctaaagc tctcttaaca acaccagggc cacttacacc aacatttata
    10081 attctatcag cctcaccaac accatggaaa gctcctgcca taaatggatt atcttctact
    10141 gcattacaaa atactactaa ttttgcacaa ccaaagcctt ttgcatcttt tgttaattct
    10201 gcagtttctt ttatgatttc tcccatttct ttcactgcat ccatatttat accacatctt
    10261 gtagaaccta catttactga agcacatact ttattagtac ttgctagagc ttttggaatt
    10321 gacttaatta gtatcttatc accttttgta tatccctttt gaactaatgc tgagaatcca
    10381 ccaataaaat ctatacctaa atcctctgca gccttatcca atgtctgtgc aaactttaca
    10441 tagtcatttt catctgttgc acctgcaata atggaaattg gagttactga taccctttta
    10501 tttacaattg ggataccaaa ttcacgctct atatcttttc caaccttcac caaatcttta
    10561 gcagaactca taatcttatt gtatattttt tctctagctt tatctccatc agggtctata
    10621 caatctaata aagaaatccc catagttata gttcttatat ccaactgttc ttcatctatc
    10681 atctttattg tttcaagtat atttcctaca ttcactatta tcacctcccc ttactgtcta
    10741 ctacagatta tgcattgaat taaatatttc ttctcgctga atttttacat ccactgataa
    10801 tttcttacct ctttcaacca agtcctcaac cgttttctca aaagaattta atgatttctc
    10861 taaatcaact atcataatca tagtaaaata atcctgtaat attttttgtg atatatctac
    10921 tatgttgata ttttgcttgt ataattcatc actaattcct gccactatac ctggtttatc
    10981 ctttccaatt actgttaaaa ttgctttcat aataatatcc tcccttattt ttttataaat
    11041 cttatatttt tacaaattga actatgtatt aacatatatt tcatttattt gttagtaaac
    11101 cactttttat gtatatattt aatatatttt aatacctata cattcatttg tcaatttttt
    11161 ttcaatattc cattattttt atactattta gaaaattcat attttatata tgttttctca
    11221 acaataaata cagttttcat aataatgaaa ggtattactt agcaatctcg tgattttcta
    11281 aataatacct ctctaaaaat tattttttta attttatgaa tttaattata ctttttctag
    11341 tatcaggatt tacaattaat atagaaccaa tcataattgg tgttagtata caaaataaaa
    11401 aaataatatc tttttttaga ttatattctt tagattctaa tttataatta ttatttatta
    11461 ttccatcata atcacttata tttgacttat ttttatttgt atcttgattt ttgttagaaa
    11521 tactttccct ataaggaaaa gaatgttcat tggtaccaaa tactgatttt gagcttaaat
    11581 cataattatc atcattttct gtaattggat ttttattgta aaatcctttt tctttatcag
    11641 aattattttc tttattaccg tctttaggta tatcatgagg atttttattt tcattgctat
    11701 cagtacttga ttctacatca tctttaggag tatttggttg tttctcatca gaattattgt
    11761 tttcattatt attgttttga ttgttattac tatcattatt ttcatttcca ttattcccat
    11821 cttgattgtt atcatcctca tctctatccg ggtcgtctct acctcctcct ccacggtcac
    11881 catcaatatc atcattttcc cgttcatcat ctggcgtctc ttggttgtct ccgcctccca
    11941 ttataaatcc tggtttaaaa actatatttg aatacccttc ttttaatcct cctaccactt
    12001 ttactctaaa acaacgcaac ttaaaatctt caaaaaaaag tatagcttga tctctaatat
    12061 cctcctgttc ttcagatatc caattgattc catcgcttga atattcaaca aaaaccttac
    12121 ttgcactata cggcatatca taaaataaaa cagctacata tccatttttt gtattttgaa
    12181 attccagttc caaattgtct attgtttttt tctctataac agatacattc aaaataggaa
    12241 ctacatcatc atttattata attttttctt tatttaacat ttctgtttta aactttcctg
    12301 ttatatcaaa attttctccc ttttccaact tttcataata atcattaaaa tcccattcta
    12361 catctatatc aagttgatta ccactagatg tttctaatac catatatttg ggaaatttta
    12421 tattttctat tttatcatct ttacttactt ttatttcatc actaaataca ccaattcccc
    12481 tatgacaaca tttcacaata ttatagccag aatctttagc tatagagggt ataagctcat
    12541 tataatcatc aattatataa actttcttac tttctgatat aattgattgt gccaacttat
    12601 tattatctct tagtaaccca ctttcattgt tgctactata tgcttttatt gaagtttctt
    12661 ctatctcaac atcaccttta gaataaacac ctatagcatg ttctccattc acttcaatat
    12721 ccttatttag tattctaata tcattttcag tataaattcc tattgcatct tttccatttg
    12781 cctttatttt ttcaacagat tcgtaggatg atttaatatg taagtctcct ccttcttcaa
    12841 cgtataaggc tgtcccatca gtagcaatta tgttgtttat accaatactt atacttccac
    12901 cattttctat atgtattact ccttcttttc ctccttcacc tattatattc aattcattat
    12961 catcaataat aaatctccca tgatttttta tcaatatttt atatttgttg gtatctattg
    13021 taaaattact gtcataagga atataaaatc taaactcttc atctattacc atatcacaag
    13081 aaagagtata aactatttct tctttattat ttttattttc ttgaacccac ctttcaaaat
    13141 cttcaagaca attttcctct tgtccaaaaa ctttatgtgg aaaacttata aaacacaaaa
    13201 ctattatact cataaaaata aatatctcat actttttcat cttacactcc tagaaatttt
    13261 ttagctttga aacaatcctg tcgaaacata tacttcaccc actataattt ttccacaatt
    13321 atcaattatt gtcaatttat ataagtatct ttattaattg ttataaataa aaagctactt
    13381 actaaagtaa acagacgttt cactttaata agtagctata tttttataac aaaatagtta
    13441 taatattaga acttccttca tttacaattt tttgtaaagt cttttgcatt ttaactctta
    13501 tctcttctgg catagtatat aatttacttt gtaattgctc ttttactaag tcatgtagtg
    13561 acttaccaaa catatttgat tcccataaat ctgctggttg ctcttcaaat acttccataa
    13621 gatattttat catctcttca ccttgatttt gatttccaac tattggagag acctctgtag
    13681 atatatctgc ttttataata tgaagtgatg gtgcattggc ttttaacttg ataccatatt
    13741 gttttccttg tttcattatt tctggttctt ccagactaag ttcttctaaa gaaggagcta
    13801 ctactccata tccttttatc ttggcatcta ttaaagcact ttctatttta tcatactcat
    13861 ttttaacttt agatagtcta gttatcagac taagcagttg ataatctcct tcaattttaa
    13921 atccactttt ttcttcaagg acattataga ataaatcttg ctttgtctgt aaatcaatat
    13981 ttataacacc ttctcctagc tctacattat caacacctgt atcttccaaa aactctaact
    14041 cagaaaatcc ttgtataata ccttctatat ctcttatttt acctatatct ataatacttt
    14101 gttttaatgt tgttattatg ctacttttta tccaatgatt tctttcaaga ccttcaaccc
    14161 attttggtaa gttgattctt atttctgtaa gtggaaaatc atataataca gcttccataa
    14221 cctcctctat atcttcttct tccatttcaa ccacattcat tggaagaact ggaacttcat
    14281 acttttcttc caattcactt ctaagcatac tcgtttcctc actttttgga cttaacgtat
    14341 ttaaaaccac tgcaaatggt tttttaagat ttttcaattc ttgtataact ctctcttctg
    14401 gttctacata gctttttctg tcaattccag taactgaacc atctgtcaag acaactatcc
    14461 ctattgtaga atggtctttt ataacttttt tagttcctat ctctgctgcc ttttcaaatg
    14521 tcatagcttc ttgtgaccaa ggagtggata ctaatctttg ttttccacct tcctcatgcc
    14581 ctaaagctcc ttcaactatg tatccaacac aatctaccat tcttactttt aaagatactg
    14641 tgtcttttat ttttatttct acaccatctg ctggtacaaa ttttggttct actgtcatta
    14701 tcgttttacc tgaaccactt tggggtatct catctcttgt tctatccttt ttaaattcat
    14761 tgtctatatt aggtataacc aacttttcca taaattttct tataaaagtt gattttcctg
    14821 ttcttacagg tccaactact ccaatatata tatccccctg agtccttttg gatatatctt
    14881 cgtatatgtt attattcata ttattcctcc tatacatcta atcttattaa attatattta
    14941 gagttaaggg ttaatattct taaaatagaa aaataaagac cagcaatatt aatttaattt
    15001 acatatagaa atttgtaaat ttcaatgtaa attaaattaa tattgctggt ccaaatagta
    15061 gtgtattata ttaactgact ttagtagtat tttcatttga cttattattc atctcaataa
    15121 gttctttacg tctttctttt gtcatgttca tccatataaa tgtaaacacc aatccaatta
    15181 tggctactat agtaagaact atgaagtagt acctatatcc agttacaccc ggaaatgcat
    15241 ccaatatctt ccctgctgct aaaggacaaa gtacttctgg aagatatcct aatgtagcaa
    15301 ctattcctat agcagttcct gatattgata atgaataatt accttcttca agtaacgaat
    15361 agtgtaaacc ttgaattgca tacatagata catatattgc aacacatcca atcaatagta
    15421 tataaatcat agatgatttt gttggtgtaa atattacacc taaaagacct gcaatcataa
    15481 gtataaatcc ataagatata atctttgatg aacctacttt atctccaagt aatccagaag
    15541 cagctgatgc tactggtcta caatactgag ctaatattga gattgcagat gcaaacacca
    15601 cagtagctcc aaatgcttca gttgaataag gcgtaaaata ataaaatgac atattagctg
    15661 aatatgaaca aaacattatt attgttatta tccatgtatg aggcattttt attactgcaa
    15721 aaaaggcttc tttatcaaat tttgctgata cctctttttc attatccttt aatttgaaaa
    15781 atactaatac tccaactatt acatttattg ccgagtataa tactataata gctgtaagac
    15841 cagatttatc acttactttt gatgaaatat acccaaatag tatcaatact agagatagat
    15901 gaattgcatt ggtaattcca cgaccacttt ccataaatcc aaaagctttt ccttgttcat
    15961 tttcagatgc taacattcta acagctttta caagagctgg ccaaaaagta agtattgttg
    16021 ttattcccca taaggcatgg attaaaaaca caacaatata tggaggataa agtgttaata
    16081 caagaccaga tattcctgta ataattaaag aacctgaaag caattttctg gctgaaatac
    16141 ggtctgctaa aaaaccacca aaaaggtatg ataccattgc aagtagacca taaatgcttc
    16201 ctaagcttcc catttgtgta tttgtaagat taaatgcttg tgcaaaagta tcataataat
    16261 aattctttaa atatggtaaa gcatatataa atgctcctgc tacaaagagt attatcaaga
    16321 ctttgaaatt tttccaaatg cttggtttat ttacttcaac tgacatactt cctccttatg
    16381 taaatacctg taaattttca tgataattaa ttattgctta ttttattgtt tattcaatat
    16441 ttcggaatat ttattaatat attaggttaa tctatcaata atttatggtg agttatgagc
    16501 taaaagtaaa ctcttttagc tcaccataat aattatattt ttatttatac taacgtccag
    16561 agttattaga tatctttttt tcatagttct tccatagcat taaacctgtt attataacaa
    16621 aaagacctcc tcctatcatt tcaatctcat agattatatt atcttttaaa gtctccataa
    16681 ctggtgccgt tgagaaaagt atgccaacta cagttactac aagtaccatt ctggcaatat
    16741 tgatacaaac tgaatcactt tttgcaattg aatatggtct ttcttcattt ggtcttgtct
    16801 ttctaagtct aatataagat gtaaaaagca agacatatgg aaataatgct gttaatgctg
    16861 tcatagtaac aagaacattg tatatattat ctactgatgg taataagttt gttcctacaa
    16921 gaagtagact cactattata gcctgaacta ttactgcatt tgatggtata ttgtatttat
    16981 ttgtaacagt caattgctta ggaaatacac cttctcttac atttccaaaa agcatcttta
    17041 ctggacctgc tatataaagt attaatgctc ctagtactga taaagttatt ccaaatgcta
    17101 ctattcttat aaaccaactt cctataccta aatcttgtgc aactttagct aatgcatcta
    17161 gtatccctgt agacgctgca attttatctg gaggaagtat cattgttatt gctactgaac
    17221 ctaagatata gattcctcct attaaaacag ccacagttaa tatagcttta ggaaagtttt
    17281 tcttagcatt atccatttcg gttatgaaat tagcagtcgt ttcagctcct gataatgcaa
    17341 atattatagc agatatagaa actaatgaat tggcatctat ttttggtatt atattttgga
    17401 ttgtatatat cgatgctgat ggagcttttt tgagaataac tacagacata aatgccatca
    17461 ctataagtaa tatagcagga attgtagaac ctaatgctcc tgtattcgta aaaaattttc
    17521 caaatgccat cccacgagta cttactaagg acaacagcca aaatattatg agtgaaagtg
    17581 ctaaaataaa catcttattg tttgataaat ctggatttcc aagcatatat gcaatattta
    17641 tagctaaaaa tgtcaagaaa gaagaatacc aaaatatctt tgatgtccaa tttagccatg
    17701 acaccataaa tccccacttc tctccatagg cttgtttaac ccattctcca agtccaccat
    17761 cttttggata tgttgcagcc aactctgcac atataagtga tgcaggaaca aagaatataa
    17821 aagcaaacaa taaccaaact ggtatagaac caagacccaa tccaaaacta gaggcagtag
    17881 atttagctat ccatctaatc ccaaatagtg ctgatatatt cataaatact aaatcccaaa
    17941 atccaatttt ctttttcact gtaattcctc caatttcaaa tttattcaaa ctcatacaca
    18001 atgtattgat ttaaatatca agtataagtt cttcaacact tcttggataa ttagttataa
    18061 ttgtagcacc attcttacct actattgctg tatctgagtg tctaaatcct ccaactccag
    18121 gtatatatat ccctggctcc atagaaaata ccattccttc ttctaatatt aattcattgt
    18181 caaatcttaa atatggctct tcatgttctg ataaacctaa accatgacca attctatgat
    18241 ttgaatataa ctctagacca tactttgcaa caacagctct tgctgcttca tccaccattc
    18301 ttgctggtat accagctttt attgtatcta atccagcttg ttgagcctct actgcaatct
    18361 taaacacttc tttttgtctt tctgttggtt tacctataat aaaagttctt tcattttctg
    18421 ctctatagtt ttcataccaa acctgtctac tatgtattac tatatctcct ctttgaagta
    18481 tcctagtatt ggaatctaaa tgaggttgtg ctgttctatc aatccctgaa caagtccagt
    18541 ttgcaaatcc tatatatgta tcaggataat tttcagaaac atattttagt aaagcattat
    18601 cccccgcaac gtcaaactcc aattcactca tcccaactct aacattttct aaagaccctt
    18661 ttattcctat atcagatagg taacctgcta tcttcaaaaa ttctatttct tttgcatctt
    18721 ttacatatct catttcaaat attttacttc caacatcttt gatagcaaat gacttatcag
    18781 ttatatactc tgaaaaactt gcagatacta tatctttttc tattccaaca gttgttcctt
    18841 tagggtattt atttaaaatt atatctaagt aatgtttatg tgatattcca tgttctttca
    18901 tttctggtat ttcataatac acatatacat tatcaacttt tgcaacttct ttagcatgta
    18961 attcttctaa tccaggtact attaattcta ttttatcttg agttactact gttacaattg
    19021 gtctagaata agttattgct ttaaatccac taatataaaa ttgattgtct ggttcaaata
    19081 ttaaagcaat ttcaatgctt ttttcattca tgtactttct caatctttct agtctcatat
    19141 tatttgacat aatgcacctc tttcttaata ttcagataat ttattcaata caacaaggat
    19201 aaatatatta ttttaaaatt cttaatattt ttagtacttg tcgtatttgc atgtaaatta
    19261 attttatttg tgattatttt atcataatca tgattatttt gtcaatcacg attttatttt
    19321 taaaattttt ttatattcta gtgattttaa attatctaaa atataacgag tatacattgt
    19381 attttggaat attattcttg atttatggta agtttaatga taaaatcacg attatataaa
    19441 ctatattgat tatttgtagg tgaataaaat gacaaataaa gaattacaaa agaaaaggat
    19501 attgatgtat ttcatagaag ctgctcaaaa tattatggaa aacgaaggta tagaaaatat
    19561 tacacttcgt aaggttgcag atatggctgg atataatagt tcaactctat ataaatactt
    19621 taaaaattta gaccatttaa tatcatttgc atctataaaa tattttaaag attataactt
    19681 gaatatttca agatgtatag aaaatgtcaa tgatgaatat aagaaatata taattatgtg
    19741 gaaattattt tgtaagcatt cttttgacaa tgctcaagct ttttatcagg tattttttaa
    19801 cttgtctagt gatgaactta gctatataac aaaacaatat tatgatatgt ttccagaaga
    19861 tttaggtatt catgatagtg acatatcttt aatgattaca ggagaaagta taaaggaaag
    19921 aaataagata ctattaaaca atcttgtaga tactggatat ataccagcta aagatttaga
    19981 cataatcaat gatataatta tttcttttta tcaaaatcta ttattcttaa aaaagaacac
    20041 aggaaaaaat tctggtgatg atgaattaac tatgaaaatg atttcttcta ttgaatacat
    20101 aataaaacat gctaaataaa attaaaatat ggctgtctca aaatagagat aagccttttt
    20161 tattgttgaa ataataaaaa tatatttaat ttcatataaa aaaaagtgcc tcgtaaacta
    20221 aaaagttcat tttgagacac ccctaaaaca aatttattat ttattataca atagtttata
    20281 tatcatcacc taaaactact tcttccattt catgcttttt acttctcatc attagttcta
    20341 ttccaacttc tttaggattt gaacctttat ttattacaga atatatagca ttagttatag
    20401 gcatatctat atctaatttt tcagcaacat catgtgctac ttcagtagca gttatgcctt
    20461 ctacaaccat ctttacttct tttaaagtat cttctaaact cataccttta cctatgagta
    20521 taccagctct tctatttcta ctatgcatac ttgtacaagt aactattaaa tctccaatac
    20581 ctgaaagacc tgcaaaggta gacatattag ctcccatagc aattccaagt ctgctcattt
    20641 cactaatacc tcttgtcata agggcagctt ttgcattatc accataccct aatccgtcac
    20701 atatcccagc tccaaatgct ataatatttt ttaatgctcc tccaagttct actccaacta
    20761 tgtctggatt cgtataaact ctaagtttag ggctcataaa taaatcttgt atcatctgtg
    20821 ctatttttaa atctttagaa gcaactacta cggtagtagg aatatccctt gctacttctt
    20881 cagcatgaga tggcccagat agtattacat atggattttg tggtaattct tcttcacaga
    20941 cttgagataa tctaagccca gtcccttttt caagaccttt agctacatta acaataactt
    21001 gtccttcttt tataaatggt tttatttttt ggcaagtact tcttacagcc tgtgatggaa
    21061 ctgctaaaac tattacctta caatctttta tagttttttc tatatcagta cttatagtta
    21121 tattgtttgg aaataatact cctggtaaat agtctgtatt ttctttagtt ctgtttattt
    21181 ttttagcttg ttcctctttt cgagtccaca tgctcacatc attacctttt tttgcaagcc
    21241 ctaaagctaa tgcacttccc cagcttccag tacctaatac acatactttc tccatgttta
    21301 acaccacctg agtataatat atttactatt ctttcttttg accaattttt ctctctgtcc
    21361 catttaataa tcgctttata tttgctctgt gattatatat tactgatgca gttaagaaca
    21421 gagctactat taaaccagct ttatttttta ccataatcat aaatattggt gaacatccta
    21481 ttcctacaac agaacccaat gaaacatact ttgttatagc taccaccaat ataaatactg
    21541 ctagacacat tagtgttatt actggattta cagctagcat tgcacctagt gaagttgcaa
    21601 cacctttacc tcctctaaat cctaaaactg ctggccaatt atgacctgct acaacacata
    21661 taactgccag atatccagct aaaagagtat ctattccaac caatcttgct gcaaattctg
    21721 atattaaaac agccattaca cctttaagaa catcacctaa aaatgtcatt gctcctgctc
    21781 tttttccaag tgtcctaagt acatttgtcg aacctgcatt accagaacct tgagtcctta
    21841 tatcaacccc agcaattcgc tttgcaacta tgtatgaggt agatatattt cctaaaagat
    21901 atgcaactac agcaataatt atataactaa atatctccac tgaatttccc ccctttagtt
    21961 atattttaag atatttattt tttatttttt tgtctatact caaactttat ggaagttcct
    22021 tcaaatccaa aattttctct tatcttattc tcaaggtatc tttgatatga gaagtgagtt
    22081 aaatccttat catttataaa caatgtaatt ttaggaggtc taatgtcagt ttgagtccca
    22141 tagtaaattt ttagtcttct acctttgtca gatggtggtt gatttaacat tacagcttct
    22201 ccaattactt cattcagtgc tgaagttgat attctcttag aatgttcatt tgacacatat
    22261 tcaactgtat ctagtatctt gttcattctt tgattagttt ttgcagaaac aaatacgatt
    22321 ggagcataca tcataaatgg aaatttttct tttatatctt ttgtgtaatt actcatagtc
    22381 ttattatctt tctctattaa atcccattta ttgattacaa atatgcatcc ttttccttca
    22441 tcatgtgcta tacctgcaac ctttgtatct tgttctgtta caccttctaa ggcatctatt
    22501 actatcaata ctacatctgc tctatctaca gcactcatag ctcttattac actgtatttt
    22561 tctattgtct catatatttt actttttctt ctaagccctg ctgtatctat tagaagaaat
    22621 ttctgtccat ttttttcaaa ataagtatca attgcgtctc tagtagttcc tgcaattgga
    22681 cttacaatta ctctttcttc tccaagtatc ttattgagta tagaactttt tcctgcattt
    22741 ggtttacctg ttatagctac tcttattata tcttcttcat actctgtatc taatcctgct
    22801 ggaaaatttt caactatctc atctaataaa tctccaaatc ccatactatt ggctcctgaa
    22861 actgcaaaag gcgttccaaa tcccaactca taaaaatcat atatattatc aaattgactt
    22921 tgactatcaa tcttattaac cactaagatt actggttttt ttgtctttct aagcaattgt
    22981 gcaatttctt tatcagcagc tgttattcca gctttaccat caactataaa aagtattaca
    23041 tgtgacatgt ccattgcaag catggcttga tttctcattt gagataatat tatatcttcg
    23101 ctatcaggtt caattcctcc tgtatccact aatgtaaaat atttatctaa ccactctact
    23161 tcagcaaata ttctatctct tgtaactcca ggtgtatttt caactattga tatccttttt
    23221 cctgcaaatt tattaaatat tgtagactta ccaacgtttg gtctcccaac tacagctaca
    23281 actggcctac ttatactcat tttatttctc cttccatctt ttgttttcta ttttaaaatt
    23341 ttatccacaa agtcttttcc ttcattcaaa caagggataa tttttattct cataagttct
    23401 tctaattgat ttaattcaat attatctaag aaaatttctt catctgcttt tagcatactt
    23461 cttgttatat aaagagcttc tcctaattct ttatcttcaa gttgttcttt taaatcctta
    23521 gctgttaaaa gacctgatac agttattgtc tctccaaaaa acttgttttt gatttcatat
    23581 acatttactt gaagattttt aaacttgtcc atcatagcat ctgccatact ctgtataaat
    23641 tcatatgcag aatgaccagt agctattgat actttcttct ctctttttag aatattctca
    23701 ggcaatatat ttagatactc ttcaatctct gtttttaact tacgtatcat acctacacca
    23761 tcttcaaact gtaaaaaacc ttcatattct tcatatccag gcaattcact attagatagt
    23821 atataaaatt catctgataa aaatgcaaat cgagtaccta atttttcaag atatttctgt
    23881 tgtatttgat gtatttgctc tatagtttta cttgcgctct tatcattaaa tatatttaat
    23941 tctactagat tttctctatg ctttgtaatc ccaactggaa ctatcgcaac actgtttaca
    24001 tatggataaa gttgagctag ttcttttatt gttctatcca attcctttcc atcatttata
    24061 cctggacata aaacaatttg acagttcatt tctatatgag catctgccaa tctcttcatt
    24121 ataccatata attttcctgc aaatttattg cttatcattt tttgtcttaa ctctggatta
    24181 gttgtatgca cagatatatt tataggactt attctatatt ttataatatt atttatatct
    24241 tcttcactca tatttgtaag tgtgacaaaa tttccttgta aaaaagataa tctcgaatca
    24301 tcatctttaa aataaagagt ttctctcata ccttctggca attggtctat aaaacaaaac
    24361 atacacttat ttctacagct tttagcttgg tcaattatcg gatttgtaaa ttcaacaccc
    24421 aaatcttcat catagtcttt ttctatctcg tatatgtaga cttcgccatc ttttttttgt
    24481 atttctacat ctaaatattc atcacttagt aagaatctat actctattat atcatgtatt
    24541 ggctgttcat tcacagatat aagtaaatct cctacctcta tacctatttc ttctgcaata
    24601 ctatctttat aaaccttact tataatatta tttacttttt ttacatttac ttccaatatt
    24661 ttcaccactc ttttgtattc atcaatgctt attataatat attttaatat gcaatttatt
    24721 tatttattat attttatgat agcattttta agcatttcat gtcataataa cacattttaa
    24781 ttctaatagt caatataagt aaatagctat aaaatagatt agaacaaata atattcaaat
    24841 ttaagtttct taaaaatttg aatattattt gttcttaaaa aaattttata aatttaatgt
    24901 tttactatga ttaacgtccc atttgtcata tcatgaacca ttccacctac acactttgac
    24961 atcaacaatg ccttattttg taagtctttc tcatcatttg cataaaatat tggacaacct
    25021 ccaccatttt tcatattctt atcaagtgta actatagcta gggtatattc atttaaacct
    25081 atatccattc ccatcttatg cacttccttt ctttcctatt ttataatttt ttagtgataa
    25141 gttttttcct ttagagcttg aaagtattgg gcatgacttt acagcttcca ttactttttc
    25201 cacattctta tctactggta aataagcaat cattatactt tcatcctctt tatttcttct
    25261 aggtaatggt acgaatgaag gttctccata atctccatat aaacctaacc ttgaatatat
    25321 attgtatact attgcttgtc tttgaccgga gtcaaataat attcctgcat tagcataatc
    25381 cttattttta ggaattattt gtattcctac acctctatta atatatactt ctctatcact
    25441 ttttagacct atatttgtta taccttttaa atctcccacc tttagtatag attcgtccac
    25501 aaaactaatt tcagcaggca ttacatcagc tatgtctcca atactttttc tagtaagaag
    25561 tttttttaat ataaaggcta acactaatcc acaaattgaa cttattacca aactcatccc
    25621 ttcacttatt ttcgtttctg caagtattac ataatacaat cctattgtta aaaaagatgt
    25681 aactatacac atataatttc ttacttcata ggttctagct atctcttcta tgaatgcagc
    25741 acctctcttt acaagttgaa cttcctctaa attttgcaat gtatttcttc tatttgctct
    25801 cacttgtcta aattgttctg ctgctagaga taaaaatgtt atggatgtat aagaacgatt
    25861 tataagagct ggaaccaata atgctcctaa tgaagaagcg acgaatgcta atataagttg
    25921 agatagtaaa acatttggtt gcgttggata ctgtttttgg tctaaattca acattataat
    25981 tctagatgtt ataccaataa taacagcaac aaaaaatact ctatccatta aatcactcct
    26041 aaaatattta atttgaaatt ttacatgtaa atctacaaag tctttctaga aaaatcactc
    26101 tgctttcctt ttgatgtttc tatgataggt gtacttttca ctacatctat catgacatct
    26161 atatctttga gtattggcat atatggtata accacagtac ttttttctaa attggtctta
    26221 gatatagcaa caatatcaac ctcatctaca tctctatcta tccccatatg aataaataga
    26281 ttatgtatta tagcttgtct ttgccctata tcatttacta ttccaaatgc acctaaatct
    26341 cttggtataa cttctatggc cagacattca tttctatact tttctcttgt actttctaga
    26401 cctatattag ttattattac atcatttacc attaaaatag gtccttcaaa acttattttt
    26461 gcaggaacta tatctgctat atctgctata ctgtttcttc ttaaaaatct tctaaaaatc
    26521 aagccaacaa tagctcctga cacaatagct aagattgtgc aatgaaaaaa gctaaggtca
    26581 tactttcttg caaaaacgat ataaactatc gaagatacta gtgcagaaaa aagacttata
    26641 taacttctag attcatacgt agatgctatt tcttcaacat aagcatctcc ttttggtact
    26701 aattcttcat tatcaatatt ctttagtgtt attctttctt gttccgcaag accttgaaac
    26761 tgttgtattg ctactgcaaa aaatgtcaag gctgcaaact ccttatctat aagtgcaggt
    26821 aatgctatag cacctaacga agctgaaagc ccagatataa ttatctgttc taaataatct
    26881 tgtggtcttg atgggtattg tttgtctgta actcttaaaa ctaatcctct acataatatt
    26941 cctacaacta atgcaactat aaaagagtgt ctaaataaat ttgcattcaa taaactttct
    27001 tccattttct cagctccttc tcttatatag tttgtgcaaa aaacaaaaaa aattcccttc
    27061 tatttaagga aatttttttg taatattgta actataaatt cgctaccaat gccaagttca
    27121 ctttttactt ttatacatcc atttagtgat ttgactatat gctttgttat agccaatcct
    27181 aaacccgttc ctcctacatc cctacttctt gctttatcta ccctataaaa tcgttcaaat
    27241 atgcgttcta catcttcttt tggtatccct acaccattgt ctataacttt aattacgatt
    27301 ttttcttcat cttttaacac tacaacttgt acaatcccat tatcttgggt atactttata
    27361 gcattatcaa ctaggtttaa gaacacttgc tttatatagt ctttattgga tagtatactt
    27421 attgatttat catcacattt atataaaact tctatatttt tttcactagc tgaatgttga
    27481 gttatttcat atacctcttt aaatacatca tatactacaa cattttccat aagaagagta
    27541 tctttatttt ctacaaatga taacagcaat atatcatcaa tcaacctttt taatctatct
    27601 gattcgcttt ctattatttc taagaatcta tttctagtat tcacatctat attttcattt
    27661 gactttagtg tttcaacaaa cccacttata gatgtaagtg gtgttttaag ttcatgactt
    27721 acatttgcaa caaaatcact tctcatattt tcaagtttaa cttttttagt aatatcttct
    27781 atatttacta tcgaacctat tattacgttg ttagtattct gaagataaac tgggtctacc
    27841 tttatcttat atacgatatc atctttagta gtaatattag cagtttcatt atctttagaa
    27901 ccaataaatt gaagtatttg ttttaatatt tcttcttctt ttattacaac attaatatta
    27961 tgaccttcaa ctaattgatt tggttcactc tttatcattt cttttgcttc atcatttatc
    28021 agaagtatat ttccatttac atctatagcc aaaattccat gagatatact ctttaatata
    28081 gatcttaact gtaaatgttt atactgtact tcttctaagg ttttatccat attctttatc
    28141 atatgattaa aatttctagc taattcacca agttctcctt tggctgatat gttaagccta
    28201 gcatgatatt cattattact tacttttttt gagacgtata taaactcttt taaatatttc
    28261 cttaatgtta ttgtatatct tacagctaat ataacaatgg ctatggacaa cataacaata
    28321 aaaaaatata tactatttaa atcttccaca agataacact cctaaaatat aaccttttta
    28381 atctatttta taccctacac ctcttatagt ctctatatat ttttccgatt tatcttcatc
    28441 ttctattttt tttcttaaat atcttatatg aacatctact gttctagttt ctccatagta
    28501 ttcatacccc catattttat ccaaaagata atttcttgaa agtacttttc ctttattttg
    28561 aattaataat tttaacaatt caaattcctt aagagttaac tctatctttt cagagccttt
    28621 ggtaacttca tgttttgata aatctagttt taaattgcct gtagtaagta tattgttttc
    28681 ttcacctaag ctagtcaaat tatatctcct taaaacagaa ctaatcctag ctaacaactc
    28741 ttttatacta aatggcttag ttatatagtc atcagcacct atttcaagcc cttcaacctt
    28801 gtcattttcc atatttttag cagtaagcat tataacagga atatttttta agtccttatc
    28861 acttcttatt tttctcaaaa cttctattcc acttatattt ggtaacatcc aatctaaaag
    28921 tattaaatct ggtttaattt ccttagcctt tataaatccg tcaaatccat catatgaata
    28981 actaacttcg taatttgaca cctccaaatt gaattttaat agctcaacta tatgcatttc
    29041 atcgtctata acaagcactt tagtattcat taaaaagctc ctctctattt tatctgtagt
    29101 accgttccta ttcgttctga tgccttatta tgttttctat aagagtggaa tttatctgct
    29161 ctacaactag tgcataaatt taaatttatt atattttctt ttttaactcc actacatcta
    29221 agcatatact cattaatttt ccataaatct aaatagtaac ttccctcttt tattatatag
    29281 aacttttcat cattatttgt aagaattgtg ttaaattttt ctactaaatc ttcagacact
    29341 tcatagcaac atggtccaat tgatggccca attatacata ctaaatcttc aggaactgtt
    29401 ttatagcatt cagacattaa ttttattgtt ttatgaccta tattactaaa agtccctctc
    29461 caacctgcat gagccagtcc tatggcttta tttttagcat ctataattga tataggtaca
    29521 cagtctgctg taaacagtaa aagtggtact ttttccaagt ttgttataag tgcatctcca
    29581 tctcttcttt tccctatagt atctttattg actatattaa ctatatctga atgtatttga
    29641 gaattactag ttatattttc aaatgtcaaa tcacattctt tacatacttt taacatatct
    29701 tctctatttt ttgcatctat attcttacat gttataacta gatttacaga atttaatttt
    29761 tcatcaagtt cttcacaatt accacttaaa ttaacatact ctttaatatc ttgtacattt
    29821 tttatattta tataatcttt catcatttgt ctcctttttc tatcagtata cttttaagtt
    29881 catttacaaa agtatttata tctttaaatt gtctatacac agaagcaaat cttacatagg
    29941 caacctcatc taactctttc aatttatcca ttaccatctc accgattttt ttggtttcaa
    30001 tttcttctat aaaacattta tttatttcat tttcaatatg tacaacaata ctttcaatct
    30061 cttcaataga aacaggtctt ttttcacatg cttttagcaa tccatatttt atcttttctc
    30121 tatcaaaata ttctctacta ttatcctttt taatgaccat taaaggagtt gtttctattt
    30181 tctcatacgt agtaaacctc tttttacatg attcacactc acgtcttctt ctgatagatt
    30241 ttaaatctgt atgtctagaa tctattacct ttgattcttt ataattacaa taaggacatt
    30301 gcatctatat tcctcctttg tttaactata tctcaaactc atctaagctt aattctgaac
    30361 ctatatttac tattattgta tcacaaccta ttttaagtat atcattccaa aatataactt
    30421 cttcatcccc tcctcttgaa aaaaaacttc tacttccgtc tccaaaaatg gtaaatgaga
    30481 ctaccttacc ttcgtgaata tccatgtcta tgtctattat aaaccccatc ctttttccat
    30541 tttttacatt tataatttct ttttccatta tatcagaaac tctaatcata ttgtactcac
    30601 cctttcttta aaaataaata tgtatcgaag taaaaaaaaa tgacctatat aggtcattta
    30661 aattaaaata atgtttacag tccatggatt acttatacat attttctcat attttttaaa
    30721 gcattttttt caattcttga tacttgtgct tgagatatac cgatttcatc agcaacttct
    30781 atctgagttc ttcctttgta aaaccttaaa tctaatacca acttttctct actatttaat
    30841 ttcttaatag cttctttaag tgatatttct tgcaaccaat tttcatcagt atctttttta
    30901 tcttgaacct gatccataac aaatattgca tctccattgt cttgatatac tgggtcaaac
    30961 agagatattg ggtcttgtat ggcatcaagt gccattacaa ctgattctac ttctaattct
    31021 aattcctttg ctatttctga tactgtaggt tctttagaat ttgttctaat taatctttct
    31081 ctaacttgta gtgccttata tgctatatct tttaatgacc tacttactct aattgggtta
    31141 ttgtctctta gatatcttct aatttctcct ataatcatag gaacagcata agttgaaaac
    31201 cttacatttt ggcttaaatc aaagttatct atagctttta taagaccaat acaacctatt
    31261 tgaaataaat cgtctatatt ttctcctctg ttgttaaact tttttattac actcaagact
    31321 aatcttaaat ttcctcttac aaactgttgt ctggcttctt catcaccatt ttttatttgt
    31381 aataaaagtt ccttcatttg cttattttta agaactggaa gttctgatgt attaacacca
    31441 catatttcaa ccttattaac ttgcatatat tttcagtcct ctctcaaaag tattcatcta
    31501 ttgaaattat ttacatttcc aattttttta tactttttaa gaagaattaa tttaacatta
    31561 tacaaatttt ttcatttctt tttgcaacct tgagattatt ttcttttcaa gtctagatat
    31621 gtaggactgt gatattccaa gcattccagc aacttctttt tgtgtttttt caataccttt
    31681 atcaataaga ccaaatctta attccataat ttgcttttct ctgtcactta atctgtcaag
    31741 tgccataacc aacaaatctc tatctatttc ttcttcaatt attttgtata tttcatcatt
    31801 ttctgtaccc aatacatcag ataataaaag ttcatttcca tctaaatcta tatttaaagg
    31861 ttcatcaaat gatacttctg ttttcttttt attatttttt cttaagtaca ttaatatttc
    31921 attttctata catctcgaag cataagttgc caattttata tttttattca gtttaaaagt
    31981 attaactgct tttatcaaac ctatagttcc tattgaaatc aaatcttcta catctatacc
    32041 tgtattttca aattttctcg atatgtagac tactaatcta agatttcttt ctattaaaat
    32101 tgactttaca ctttcatctg tttctagctt ttgtaaaagc tccatttctt cttctggttt
    32161 caatggagga ggaagtatat ttgcccctcc catatagtat attccctttg gctttattat
    32221 ttttaattta atacctaaca tagtaataaa gcttattatt ctttctttca atcgtaacat
    32281 tccttgtccc ccttaaattt tcacctaaaa tccaggcaat atatttggat tcattattgc
    32341 tccatattct ctatcattaa aatttgaaat accaagtatt atatttccta tcttttgctc
    32401 atctacttct atatagtcag cttttaagcc tattattatg cttgtcttat tacttccagc
    32461 atgtttataa ggtattattc taactctacc tgaagtttta tcatctaaac ttcctataat
    32521 ttcttgtgct ttcttcatat ctatatcttc ataattaata tttaatagtt tttctggaat
    32581 aaatccttct aacacactag acttaactat tattacatca ctttgactta ttgggtcttt
    32641 taacaaatta ccactatcta ctaaagcttt acagcaaaaa cttttttcta gtaagtttat
    32701 atttatagtc tttgtaagct ccttaatgta cttaagcatt ttcaaatctt tataaatgta
    32761 ttttaataat tcacaactca cataagtaca tgcaattaag aaagatattt ttaagtgact
    32821 tattcctgta aaataaatta taaaataagt gcttccagaa ataaaaatgt ttactagata
    32881 aaaaactaac gctacatgaa cataatcttt tttgctctta cttctaaatg aaattaaagt
    32941 tattatgctc atgattatta ttttaaatgg tacagtaaat agtatattca ttgatggata
    33001 caaataagca acagaatagg cacttcctaa actagccccc aataacttat tttttttagg
    33061 attatatctt ttagtaagaa tagaagtaca acttataata atataattta ttactaggtt
    33121 ttctataaca tagtactcaa tatacaccat gtatcccccc ttaaaacctt taaacatatt
    33181 ataagatagt atgtacaaaa ttttatgtca cttttgatgg tcgaatccaa aacaaattct
    33241 atttaaaaag aacaatgata tatgtcttat actttatgtc gtcaaaagat atttttttaa
    33301 tgccaaacag atagactttt ttgtagaatc caatatatct aggtagaagt tattcgcttt
    33361 acttttggta tatttataaa aaaaagacta cataatttaa taatatatca agtaaatctt
    33421 ttacttatat aaaatcaaat tatatagtct gtaaattcaa atataaatta ttgtgctagt
    33481 aatccatttg catattttgc agattcattt agtgcttgtt ctggagttat gtctccagct
    33541 atcatcattt gaagttgttt ccataaatat tcatatatct ctactccatg aggtccaact
    33601 gtcaatggtc tatacatatg tttatctctt gtcaccattt cttcaaatct tgggtctcct
    33661 tggtattttt cacctttagc aactggagct ctaggtattt ctttgtggaa agcttccatt
    33721 gattctttgc ttagcatata ctcaagaagt ttaaatccaa gttctttatt tttacatgct
    33781 gacattaatg ttaaatcatc tactgaagca aaacttccaa ctgtcttatc ttctaatgat
    33841 gttacatatc cccagtttaa atccgggaat gatttatcaa atgtacttgt agcagcagag
    33901 gatagcatta tagtaaatgc agcttttcct ggtccaaata cactctcaat catttcatta
    33961 ctatcttttg ataaagcatc ttctggaata tactttttca tatcatttat aaagtttgca
    34021 gctttcaagc cttctgcatt attaaattta actgatttta aatcatcatt atatatatct
    34081 ccaccagctt gccataaata cggataccag ttccagttta agcttccaaa tactttagaa
    34141 ccccaacctt gtgcaagacc ccactggtcg atttttccat ctccatcagt atcttttgtt
    34201 gctttttcac agattctttt aaaatcatcc catgtttttg gaggtttttc tcctaatttt
    34261 tctagtatat ctttattgta gtacaatacg cctggattag cagcttctat aggtaaacca
    34321 taaataccac ccatcatttt tgcatcatct aagtatagat aattatctga agttcctgat
    34381 ttttctaaat aaggtgttaa atcttctacc gcacccattt ctataaattg agggaacatc
    34441 tctgcataca tgtatcctat atctggacct tcacctgcac ttattgctgt tgcatatttt
    34501 tctgcgtagt tatcccatgg cactatctga aattcaattt cacagttatt ttctttttca
    34561 aatttttcaa atatcggctt ccatgcatct gcgtcatggt ctgttaatgg tgcagaccat
    34621 acaactaatt tttctttacc ctctttgcct ttagaatctt ctttttttga acatcctgca
    34681 agaattgata ctgatagaat ccctaccata actaaagaaa gaaccttttt tagtttaatc
    34741 atgcttaatc ccctttcaga ctttaatttg tctttttcct caaatgttta catttaattc
    34801 agatttaata ttaacaaata agactactct tgtctaatca taaaaaacta tactaactcc
    34861 tataactata ttttttttct atacctatta gatttaattc atactaaaaa cttacttttt
    34921 aaattttatc aatatttaaa aatattttta agtctagcca caaactaact atctaaattg
    34981 aacaaaataa aaagaagtct attgacttct ttataagctt acatattatc ttcttcttct
    35041 taggaatgta ggtatctcca tgctctcatc atcatcttct tcaattatac ttgccttttt
    35101 aggaggctct attttttcct cagcaattac ttcttcttca atttctttta cagcttgttt
    35161 tactgttgta tttaatgaag aacgtatgct tgatttaggt ttagtatcta aatctaaggc
    35221 accattttgt aatccttcaa atcctgttgc gattactgta atcattattt catcacctaa
    35281 atcttctttt atagaagctc caaatataac atttgcttct gggtcacagg attccataac
    35341 taaagttgat gcctcattaa cttcaaataa tcctaagtta ggaccacctg taacattaag
    35401 aagtactcct ttagctcctt gtattgatgt ttctagaagt ggagattgaa tagcttgtct
    35461 tgcagcatca attgctctag tttcaccact agcactacct atacccatat gagcaagtcc
    35521 cttgtctttc attatagtag taacatctgc aaagtccaag tttattaacc cttcaactgc
    35581 tataaggtct gaaattgatt gtataccttg ttttaataca tcatctgcaa ctgcaaaagc
    35641 atctaacatt gatgtatttt tttgtactat ctgtaaaagt ctatcatttg gtatcgttat
    35701 aagagtatct acttttgatt taagttctgc tattccacct tcagcgttct tcattcttat
    35761 cttaccttca aatgcaaaag gtttggtaac tacacctact gtaagtatcc ccatttcttt
    35821 tgccaagcct gcaaccactg gagcagctcc tgtaccagta ccaccgccca ttccggctgt
    35881 tacaaagacc atatcagctc cttgaagtaa ctttactatt tcatctttac tctcctcagc
    35941 agctcttttc cctacttctg gatttgctcc tgctccaagt cctctagtta atttttctcc
    36001 tatttgaact ttatattcag cttttgatgt atataaagct tgtttatctg tatttactga
    36061 tataaattca acgcctttta gttgagcttc taccattcta ttgacagcat tgtttccacc
    36121 gccacctaca cctattactt taatttgtgc acattcttct aattctacgt caaagtttag
    36181 catcataaac ccccttctct catgattcaa agttatcgta tgtattaatt atatcatttt
    36241 cttcttttat tttgttaacc tttaagtaac atattccaca aaaacgtaaa ttttcctttt
    36301 taaatttctt acttatattg tcaaatatta ctctttaagt ataaaataat ttacgtatat
    36361 attaaatgct ctttaatttt tacgtttttt gttcataata ttactaataa tatatcgtct
    36421 aattatagat aagttattaa acaatctcat accaaaaact agtacagcaa catagtaaag
    36481 agaaactcct aacttttctc ctatataagt caataatata gccaatatag cattacctat
    36541 gaaaccagta ataaaaatta cattatcata gttatcttca aaattggatt ttatcgctcc
    36601 aaaaatagaa tccattattg caagaatagc tactgacata tatatggaat aatccataga
    36661 atatgtaaat ggaatatagt aacctactac tacaccaaat gctaatcctc ctaaaaccca
    36721 caacataaat cttcacctct ttattttact ttgaaacaca actacattac aatccttttt
    36781 attaattttt tttacttttt ctttattttt ttgtattttt cgttttattt tgcaaataaa
    36841 ttcactttat ttccattatt ttcctgaact tttatattaa ttccatatat atccttaaga
    36901 gatttagcat atgattctgg agagtttata gctgcactca ataaatctat atctcctata
    36961 gcttttatta taaatggttg tccatatgta gtatcattta ctgtaatagt agctcctgaa
    37021 cattttatct tacttgttgc tagtactctt tccccattta tagaaattgc tcttgctcca
    37081 gcctttttta aatcatttaa aactctcaaa atatctatat catgtataat caaatcattt
    37141 ggattctgtc cgtcttttaa ctctctctca ctatccctca tagtaatagt tatgcctggc
    37201 cctgtaacag ttgaataacc acttaattct ttaacttctt caagctcttt ttgcataagt
    37261 gtttggatag attcatttcc attctttttt gcttctttat attcattcaa agtttttttg
    37321 ttgtttttaa gagtttcttt taaatttttt atttcttttt ttgtattttc tacctcactt
    37381 tcaatacttt cagtttgacc taatgttatg tatactctat ttgggtctag tgattttata
    37441 taagttgata tgaaaatgcc taatatgaat gctcctaata taactatttt ctttttcata
    37501 ctattatttc ccctctgctt tgtttatatc actatgacca tttatttcta tattgtcttc
    37561 tttggtcact tttactttgg cattataata tgtttctatt tcccagacaa taccatactt
    37621 tatattaagt gccgaagcca atgtatcaga atcaccaatt gcttttatta taattggttc
    37681 ttttatgaca gtgtcattca tataaagctt gtcttctttt aaatacatat atgtattaaa
    37741 aactattctc tggtcgttta tagatatggc acttgcttgt gctgaattta atttatttat
    37801 cattgacaat aataaatcat aattatatag tatactatca tttttatcag agtttcctaa
    37861 gtcttttgta gaatttatct caatttttat gcctgttcct tcaacatctg tatatccagc
    37921 taatgtttca tatttttcta tttctgactt aagtatgtct tgttctcctt tattgttttt
    37981 gcctctataa gtctctatat ctttcttcac actattaact tctgattgta gattctcttt
    38041 ttcttttttt aaagatttaa gttcttctgt aagttgctct cctcttttaa aagttgtcat
    38101 ccctctattt tctatattaa taattttaag ttgtaaacta acaagaacac ccaatacaac
    38161 acttcctatg attatacttt tatttataaa tctttttttc aatatatcac ttccttacaa
    38221 ttgtctatcc ttctggacta tacactgcca actttccata gttaagattt atagtccctc
    38281 cattagtatt tttattttgc aggtcaatca gaattttact taccctagat atattataat
    38341 ctaagttatc atcattagaa agtaagattt ttatattact tcttgtaagc atttctatat
    38401 tgctttcttt ttttaagttt acataattta tttttctata aattccttct tcttttaaat
    38461 aatttaaagt tttaaataca ttctccttag ttttataatt tttaaatttt atagatttat
    38521 tatcatcaac gctataatct acatctacta tcaagtcttt tttactttca ttagaacctc
    38581 ttagttcttc caataaattt ccttttttat ctatataaca ataattatct tcatctttta
    38641 atactgcaaa tatttctttt tcttttaaac ttataattat cttattggga agttttcttt
    38701 ttatttccac attttctata tatggatttt ttataagttt atttttcata tctttaaaat
    38761 tgtatgcaaa aatattttca tttagattta tatttagttc tttcattata tttgatttgg
    38821 tcaccctctt atttccaatt acatctattt tctttacatc aaataaatca ctttttacaa
    38881 ttatacatat acaaaaagat aacataagta taaaaactaa aactatcatg acattattcg
    38941 tatttaactt tcttcttttt ttcaaatata atcaacccct ttggttaata aatacacctt
    39001 tagagcttgt ttttcctaca aaaaaattat aatatttaaa gtcaaatttt tgcattttat
    39061 tacataacat ccaaataagg tattaaattt tataaataaa tcaatatttc atcaaaataa
    39121 acatagtata ctacatacta tttatatatt taaatctgta tacatacaaa taaaccccta
    39181 atttataata atttagaaaa tctaatatat tataaattag gggtaaatat ttacttatct
    39241 tttctttatt cctattacct tagcttgacc ttctatactt ggagtcgttt ctttttttat
    39301 ttcttttact tccttaataa ctttttcttt ttttgttttt ttagaagttg acttttgtgt
    39361 tgaattgtat actttcatta tctcatcata tataaggtct atggcttcag gcttacctat
    39421 agttttactt gcatttgcca tatcaactaa aagttctcta tctcctaaaa gtttaaatac
    39481 tgctgtattt aggctctctg gagttagatt tttttctaaa atagcaattc ctgccccttg
    39541 tttttctata ctcttggcat tatactcttg atgattttca gcagtataag ctttaggtat
    39601 tattatagat ggctttccaa gagccgttat ctcagctaat gaaattgctc ctgcgctacc
    39661 tataactaaa tcacttgctg caagtgcatt tgccatatct tctaagtaag gcacaacttt
    39721 ttggtatggt ttaagattta tatcgctaat acttcccata aattcatcat aatagctttt
    39781 gcctgtagca aatataaaag ctatatcttc atttaccata ttctttatta caagtctcat
    39841 tgcatcattt atttttcttg aacctccact accaccatag caaagtacca ttcttttttc
    39901 gtcacttatt gatagattct ttcttgcaat attttttctt gataataaaa tttcttttct
    39961 aactggattt cctgtaaaaa ctaatttatc ttctgctgcc tctggaaatc ttttatgcga
    40021 atcttcaaaa cttgtaagta cctttgtaac tgttttagat aaaatcttat tagttacacc
    40081 aggaaaagaa ttttgctcat gtattatggc tggtattttc cccatagatg cattaaataa
    40141 aacaggtcca ctaacatatc caccagttcc tataactata tctggtttaa atttcttaac
    40201 aatctttctt gattgctcca aacctttaaa aagcttaaaa actcttttta cattatcgaa
    40261 atctattttt cgcttaaaac cttgaactgt tacagtcttt aattcaaatc catacttagg
    40321 aactatttct gactctattc ccttttccgt cccaacaaaa attatctcag cgtctggatg
    40381 ctcatctctt attttgtttg caatagctat agctggatac acgtgccctc cagttccacc
    40441 gcctgataat aaaactttca tcaaatcatc atctcctgtt aattaatttt gacatgcttt
    40501 gagatgttta acactattcc tacagctccc ataaagatgg tgagtgaagt tcctccataa
    40561 cttataaatg gtagtgctac acctgtagct ggcattgatg atgtcgcaac tgctatattt
    40621 aaagctgctt gtattccaat ttgtgcacct atacctataa caaccataca agcaaataca
    40681 ttagaagtct tcaaagctat tcttacacat ctgtagacta aaactacaaa tagcataata
    40741 actattatac aaccaatcaa tcctaactct tctcctatta tagcaaatat aaagtcattt
    40801 tgtggctctg gtatataaaa atacttttgt ttactctttc ctaagcctag accaaacaat
    40861 ccacctgaac ctagtgcata tagaccttgt attacctgat accccttacc aagaggatct
    40921 tgaaaagggt ctaaaaatga tgtaacacga ctaagtctat agggttcagc aattactaat
    40981 gcagcaaata aagcagcccc actccctatc atagcaaata caattttcat atccattcca
    41041 gcaacaaata tcattacaaa agtaactaga attacagtac ctgctgttga caaatttggc
    41101 tgaagtatta tcaacgcaaa aaatatccct ggaactacga gaagtggtac aacacctttt
    41161 gtcaaagatt ttattttatc ataatttttt tcaattaatt ttgcagttaa tattattgta
    41221 gcaaactttg cgatttctgc aggttgaaat gttaaagctc ctattcccaa ccatcttttt
    41281 gctccgtttg cttctatccc taaaggggtc aaaactaaca ataataatac tactgctata
    41341 gctccaattg ctgtagcatt tttcttccaa aaactataat ctattcttga tgtaataatc
    41401 ataactataa atccaagtac agcatatatt acattctttt ttagaaaata gtacgcatca
    41461 ttgtgtttaa atgaagattg tataaaactt gcactaaaca ccataactat tcctacaaat
    41521 actaaaagca tagtagtgta aaacactact ccatcaaatt cagtcttcat ccttatgtca
    41581 atttgttttt tcaaattttc tttaggcatc caactaatct acctccattc ttccatttaa
    41641 gtaagtttag aggtaagaga ttattttaaa ttgtttacat tatctttgaa gtcttttcct
    41701 cttacttcaa aactttcata catatcccaa cttgcacaag ctggtgaaag aagcactata
    41761 tctccacttt ttgaaatttc ataagaagtc ttaactgctt cttccatatc ttttactata
    41821 tgtatgtcat taaatccttt atttttagca caattttcta tatttgatgc agtttctcct
    41881 aataagacca atgatttaac atatgacttt gcagtttcaa gaagttcatc aaaattactt
    41941 cccttatcca tcccccctgc tataagtatt ataggtctat cataagactg tatagctttt
    42001 atagtggaat ctggattagt tccctttgaa tcatttacat atattacatt gtctaaattt
    42061 cttacaaact cttgtctgtg ttccactcct ttaaatgtca taagtacatc ctttataact
    42121 tctaaatcaa ttttgcagac atatgctatt gctatagctg ccatacaatt ttctaagtta
    42181 tgacctccag gtaaacttac atcatcttta tttagaaatt tgattttatc atctatatct
    42241 attattatgt cattattttc taaatatact cctccattta cttttttagt tcttgaaaag
    42301 taaattactt tggcattgca tttatcagct aaagatttta ctacctcatc atcatagttt
    42361 aacacacaga aatcctcaac agtttggttc ataaatatat ttgcctttgc ttctatgtat
    42421 ttttccatag tatggtgtct atttaagtgg tcctctgtaa tatttaatat tgcgcttact
    42481 ttaggtctaa attcatctat actctcaagc tgaaaactgc ttagttcagt tactaacaca
    42541 gactcttcac ttgaagtttc tatagtatct attacaggat ttcctatatt accaactaca
    42601 tatgtatctc gttttgctct tgaaaaaatt tctcctacta aactagttgt agttgtcttt
    42661 ccatttgtac ctgtaatccc tataaaaatt ggattattcg atagtttaaa agctaattct
    42721 acctcaccaa ttatatactt gcctgaattt tttaatttca atatgaatgg taggtctagt
    42781 ggtacacctg gagacactac aaccatatct atatcatcta catcttctgg gtgatgtcct
    42841 aatatgtatt ttatgtcatt tatagatttc aattcatcaa gtatatttct caatttattt
    42901 tcatctttta tatcatttac gattatactt gcacccaatt tatctaaatg tttaattgta
    42961 gatataccag tttttgcaag tcctactaat aaaacttttt ttccttttaa gtccattttt
    43021 cattccccct agccctaaaa tactgctatt atacttatcc aagctaaaac aactgttata
    43081 atccaaaaaa taaatacaac tcttgtttct ggccaaccac actgttcaaa gtggtggtgt
    43141 attggagcca tcttaaagaa tctctttctt gttgccttaa aatatccaac ttgaatcaag
    43201 actgatagag cctccgcaaa ataaattcct ccaattatag gtattataag cactgagtta
    43261 gttagaactg aaaatgctac aactgcacct cctaatgcca ttgaacctgt gtcgcccata
    43321 aacactctag ccggatatga attaaatcct aagaaaccta aacatgctcc aacagttgct
    43381 gctgctaaaa ctgcgacttc tgtatttcca gcaatagaac ttgcaaatag cataaagaat
    43441 acagaaacta ttaatgttac tcctgatgct aatccatcta atccatcagt caagtttaca
    43501 gcatttacta ttgctacgat tataaacatc attattggta tatataatat tccaacattt
    43561 atcacaaaat ctgtaaatgg tatcataagt tgtgaagcac ttgatgatga tgtatactga
    43621 taaaaagcaa cataaaaaga taatgcaact tgaaggatta ttttttgata tgcttttagt
    43681 ccaagtgatc tttttagctt tatttttata aaatcatcta aaaagccaat aaaaccaaaa
    43741 cctgcaatac atataagacc tactgccata tcatgactaa cttttactct tgtaagtcca
    43801 gttattagaa ttgcaacaat cattataatt ccacccatag taggtgttcc gtttttagct
    43861 agatgtgttt ggggtccatc atctctaact gtctgaccaa atttaaattt tctaagcatt
    43921 ggtataaata ttggtcctat tataattact attaaaaacg caatcaatgc ggtgtacgta
    43981 agctctgtta ttcctaacat cataaaactc ctctcccttg tcaattaact cattagttta
    44041 agcttattta tttagatatt cgactatttt ttctaatctc atgcctcttg agccttttac
    44101 taaaatagtg tctcctgttt ttactaattc atttaacttg ttaaacacat cttctctatt
    44161 ctcaaagtga tatatattgg ctgaattgaa tcctaattgt tttgcttctt ctccaataaa
    44221 cactgaattt tcacctatag ttattataat atcagtatta ttcatagatg attttccaac
    44281 taatctatga ccatactctg aaatttcacc catttctagt atatctccaa gtatcgctac
    44341 ccttctacct ttatatcttc caagtatctt taaagcagca tccatagaat ctggactagc
    44401 attatatgaa tcattaatta ttgttaattt ttcatttttt attatgtcta gtctcatttt
    44461 tgtcccttta aaatttttta aacctttttt tatataatct aaagaaatat ttagacacaa
    44521 accaactaat atagcagaca ttgcattata tatattatgt tctcctattg ttggtataaa
    44581 tatttcctct tttttcccat ttattacaca tataaatgtt aaactatcct cttccatagt
    44641 ataactttca caataaatat cattgttttt attaaagcca aatgttttta acttatatac
    44701 atgttctttt tcttttaatg tagataaaaa cttatcatct ccatttacaa ttaaagtatt
    44761 tgtttcatca aagtttgaag taatctccat ctttgctttc aaaataccct cttgtgaacc
    44821 cagtttttct acatgtgata atcctatatt cgatatgact gcaattttag gatttactat
    44881 atccactaaa tattttattt cattgaatcc agacataccc atctctatta cagcacactc
    44941 atgttcttta tttagattaa ataaagtcaa tggaactcca aaatgattat ttaagttttt
    45001 ttcatttttt agtatattta actttgcaga tatggcagag taaatcatat ctctagtagt
    45061 agtttttccc acactacctg taacacctat aaatggaata tcaaattttt ctttatagta
    45121 ttttgaaata tctcctagag ccaaagatgt atcttttacc tctattaaat ttatatccga
    45181 actttctaat tttattccat tactttcatt ttttataaaa gttttacatc cactatcata
    45241 tgcaggcttc ataaatgtat gcccatctaa attttctcca actatggcta caaatgcatt
    45301 ttgggcactt gcctccctgc tatctataac tatatcactt acacagtcat tataatctcc
    45361 atatattaac ttcccattag ttgcaagtac taactctttt attgttaagc actccattat
    45421 taaactcctc ctttaaaacc ttagctatat tctcttagca acaaaaggca atgtataccg
    45481 ttatatatac attgcctacg ataactctta actttataat tatatactat atttctgttt
    45541 ttttgaagat gtttatgggt atatgttaat tatctgttac tttttagttt tcaaaatata
    45601 gggttatact tgagtcttca ttaactttta ctccaggttt tgggaatata tcctttacct
    45661 ttgtatcttc tggaagttct atatctgcat ctaagtctgg ttttaacttc gcatcctcca
    45721 atgcctttac agcatctcct atttttagat ttcttacatc tggcacttta acttgcttct
    45781 tttcatactc agctttttct tcttctttat atactggttt aactcccaaa tattttaaag
    45841 agtcattcat tatttctttc actattggtc ctgctgtagt actaccaaat gcacttactc
    45901 ctgttggttc gtcaacaata gcaagaacta ctatttgcgg gtcatcacaa ggtgctattc
    45961 caacaaatga acatatatac tttcctggag catacttacc atctataact ttttgagctg
    46021 tacctgtttt accaccaagt ctataccctg gtatatatgc tatctttcct ccaccttcag
    46081 ttacaactga ttctgcaatt tctaacattt ttttagatgt ttctttagat ataacacttc
    46141 ttactttttt tggttttact gtttcagtta tatttccttt attgtcagta taagatttta
    46201 ccactcttgg ttgcattaaa tctccaccat tagctattga tgatatagct gttataagtt
    46261 gtattggagt tactgatata gattgaccaa atgatattgt agccaattca actggtccta
    46321 catttttttc gttatacagt attcccttag cttctcctgg taaatctata cctgtcttat
    46381 ccataagacc aaatgattct atataatcat acatttttcc aacacctaat ctgcttccta
    46441 attcaacaaa tactgggttg caagagtttt gtactgcttg tttaaattct tgtgttccat
    46501 gaggtctgta atgtctccaa catttaatct ttcttcctcc aacagttaca ctacctgtac
    46561 atgtgaattt ttctccatct ttaattactc cctcttcaag agcactggaa gatgtaataa
    46621 gcttaaatgt agaacctggt tcatatgtat cacttactgc tggatttctc cacatttgat
    46681 aatagccttt tattttatct ttatcattat atttttcaag ttcttcttga taatatggat
    46741 atattggtgt tcttgagtca ttagggtcat aatctggttt tgatgctaaa gcaagtatat
    46801 cacctgtttt agggttcata gctattgcag taaccttttt tgcattattt aactcataag
    46861 ctttctgtac tgctttttca gtatagtgtt gaattacttc atctatagac aacacaagac
    46921 cattaccttg tacaggctca taatattttt ccattccttg tggtatttct cttcctgagg
    46981 catcagtact tactataagt tttccaggct ttccttttaa ctttttatca tattgcattt
    47041 ctacaccaga tatacctgtt gcatctgaag aagtatgtcc taacacatat ggcgcaaaat
    47101 tcccatatgg gtaatatctt tgattatctt ctgctaccca tattccactt aatttagcat
    47161 ctcttatttg acttgcctta tcatcatcta tccatctttt tacttttaca agagccatat
    47221 tttttttgct tattaaagcg taaatatctt tataatcttc atccaaaatc tcagctacct
    47281 tttcagctgc ttctttttta tcttctactt ccacaggttt acaccaaaca gtatacttag
    47341 ttacacttac tgctaattct ttcatatttc tatcatatat agttcctctt ttgggttcta
    47401 ttggtatatc tcttgtttgt tgttctagtg cttttgtact caaccaattt cccttcataa
    47461 gttgtaggta cccagtccta ataacaaggc aaaaaaacaa tgcacatgct agaataagaa
    47521 cgagtaccag ccttttctta cttatcctct ttacttttct caaatctatt ccccctagtt
    47581 atccacatct atatacttta tttgtccatc ttttggatag tccatattga gcaattcctt
    47641 agcctttagc tcaatttctt ttattgatgt tttttcagtt tcttttgcct ttagttcctc
    47701 taatactatc tctttttttc ttaaatcttt ttgtaaataa tagatatcgt acttcatttc
    47761 cgagattttt gaataaccac atagattcaa tattattact gaaaaagttg caatcagtaa
    47821 aatgcattta gctcctattt ttttcttatt tctcttttta taattattct tttttttatt
    47881 tttatattca tttagattat gtattttata attttttttc aaattctcac cccgatagta
    47941 tatagtttaa attttcctct atactatatt tgttattaat catatttctt cctctaaaat
    48001 ttcatcgcta aattaataca ctattacaca atctaattgt atttttttct atacacaaca
    48061 aaaacctata aattcactta tacttttata tgaatctata ggttagatat taatttctat
    48121 ttatttttat cacttctagt atttttagat aatttcttcc ataaatataa tatgtaacta
    48181 actatctact ctctgattcc taagttctcc attatattac ttaataccat ctatatctat
    48241 atttttatat ctaaattttc attatatatc tcaataacca agaacatttc ttatagtgtt
    48301 aattgttttt taattgcttt accagttcaa caaaatatat aatacttttt aattaattat
    48361 aataatctta ttttatatat aagattattc tttagcctta taactactta tattttttct
    48421 gctactctta gcttagcact tcttgaacgt ggatttactt ctatttcttc ctcactaggt
    48481 aatataggtt ttctagttat tattttcacc tcagattctt tatcacattg gcatataggt
    48541 aaatgttgtg gacatataca atctgatgct aaatgcttaa atgcattttt cactattcta
    48601 tcttctaatg aatggaatgt tattatacat attcttccac ctttattcat tatagaagaa
    48661 gcatcattta tcatctttgt aattactcca agttcattat ttacttctat tcgtattgcc
    48721 tgaaaagttc ttttagctgg gtgaggtcca tctattctag ctttcttagg gatagctttt
    48781 ttaattatat ctactaattc tcctgtagtt tctattggtt tgtttgctct ttcttcaact
    48841 ataaatttag ctatacgctt agcccagtta tcttctccat aatcttttat tatcttagtt
    48901 aattcatctt ctgtataagt atttacaaca tcatatgcag aaaactcaca cctaacatcc
    48961 attctcatat caagtggtgc atcttgcata taagaaaatc ctctatcagc ttcatcaagt
    49021 tgatgagatg aaactcctaa atcagctaat acaccatcaa ttttgtaaac tcctattttt
    49081 tctaattcct cttttatatt ttcaaagttg ctgtgaacaa acttcactct actttcatat
    49141 tcactcaatc tctcttttgc tgtgcttata gcatttttat cttggtcaaa ccctataaat
    49201 aatcccttat ctgacagttt ttttactatt tctttagaat gtcctgctcc tcccatagta
    49261 cagtcaacat acacgccatc tggctttata tttaaattct ctatacactc atttaaaaga
    49321 actgatacat gatgaaattc catagttacc tcccttaaat tcacttttta aactattctt
    49381 cactaatatt atttttattt ttctttgata aataaacatg tgcaattatg ccaccaataa
    49441 ctccaattag acttataact tgtgccattc taagtggtcc taacattaaa ctatctgttc
    49501 ttaatccctc tataaaaaat cttcctattg aatataaagt tatataagta actataactt
    49561 gaccttcata ttttttattt tttctaaata gtaataaaac tataaatatt ccaaaatccc
    49621 atatggactc atataaaaaa gttggatgta cctttactcc atcaaccatt attccccaag
    49681 gtaaattggt agcacctcca tgtgcttctc cattaataaa atttccccat cttccaatag
    49741 cttgtgctaa aggcattcca agtataactg tatcagccat ttttaagaag ttaatatttt
    49801 taatcttagt gtatatataa ccagctaata ttccaccaat taaccctcca tgtatagcaa
    49861 gtccaccacc tctaaaatta aaaatttgag acatattttg agcatagtaa ctccaattaa
    49921 atacaacata atagattctt gcacagatta gtccaactgg aattgctatt atagctatat
    49981 ttaatacatc atcttcttta attcccactc tttttgcttc ttttattgct attaaagttc
    50041 ctaaaatcat tccacatgcc ataagtattc cataccacat gatgtctatg ccaaacagtg
    50101 taaatgctac tctatccata acgtcacctc tttgtattaa ttgaaaatat ttccaaagca
    50161 atatgctata attacaatta attgtaatta tactaaatta tgataacaca ttaatgttaa
    50221 ttctacaaaa aatattaaaa tttattctac aaatccctac actatattat actaatctaa
    50281 ttactataaa attttttaaa ctgaatctct catgactaaa gttacaagtg tacatagata
    50341 ttttttaatc aaaaagattg atgcatatat acatcaacct cttctattcc ttatctatag
    50401 ctcttaaatt tttacctcaa tttatataaa tatattttat aaatttgttt taccaaaata
    50461 aacatttaaa aacataaata atacttaatt agttattctt attatgatta agtttctatt
    50521 taggctctac aatagaaata acacaatact cttctttaaa atgctctttt aatctttctt
    50581 caacttcctc aaaagtaata tctttaataa catctaaata atccaataga tttatatcct
    50641 taaaaacata agatataaaa ctattaccta taaagtttat agaatcaaag cacttaataa
    50701 atgaccctat ttttttcttt ttagttctct caaactcttc ttttgataat ccttcttttt
    50761 ttgatttttc tatataatca agaattattt cttttacttt tttaggctct ttagaatctc
    50821 cagctattat gctaaaagca taatccactt gagacgaaaa tccagctcca aaattttcat
    50881 ttattaaacc ttgcatatac aaatcttcat agagcttact tcctttttta aataacatcc
    50941 ctacaagtat atcagttaca atctctttac gtaaaagttc tttccctttt aaaccaacat
    51001 tactatcttt aaaacctatg ttgaacatag gcatagatat agggaatttt tctataacct
    51061 ctttttcttt tacactttct ggttcttctg gataaaatct ttctatactc ttagagagtt
    51121 tgtctacttt gtaattgttt gactttttag ttacatctat aactttttct acatctaagt
    51181 caccaacaac aaataaagcc atatttcctg gattatagaa agtattataa catttatata
    51241 gctcttcctt agttatctta tatatactat caacagtacc tgctatatca attctagcag
    51301 gataatttac atacattgcc ttcaagcaat taaagtatac attccaatca gggtcatcat
    51361 tgtacatttt tatctcttgt gctattatac ctttttcctt ttcaacattt tcatctgtaa
    51421 aataaggtgt ttgaacatag tcaattagat gttctaaact ctcataaaaa ttttcagtag
    51481 cagaaaataa gtaggctgtc attgtaaaat tagtaaatgc atttgcattt actcctaatt
    51541 ttgaaaattt atcaaatgca tctcctccat caggttgctc aaacatctta tgctctagaa
    51601 aatgtgcaat accttcattc actctaattt tcttatcttc tccaattggt acaaattcta
    51661 agtcatttga accataatta gtagccaaaa tagcatactt tttcataaaa ccccttttag
    51721 gcataaaata tacatctaat ccattttgca atttctcata ataaacttct tctttcaata
    51781 tatcattaac tattttttcc atagacatct cctccattaa tttctcaaga agtatacagt
    51841 atcaagctct atatttttta tagcttcaac tatatctttt tttgtaacct tttctatact
    51901 agatattatg tcttgtactt cagaatttgt ctttgccata gactgagaga aaacaaaatc
    51961 agacatacca cctatattat cagttataga tttcatagaa ttaactaaag caagtttact
    52021 gttttctaat tcttcatcag atatatcacc tgcttttaca ctttctactt gtttttttat
    52081 caattctaca gctttatcat aatctttagt ttctatacca gatgatataa acatgatact
    52141 tttatacttc tctattgaag agaatatata gtaacataaa ctttcttttt ctcttacatt
    52201 aacaaataat ttagagtgtg gaccaccacc taagacattg ctcccaacta ctaaagcata
    52261 atatttatct atgtctgcat aatccacatt tgctctataa cccataacta acttaccttg
    52321 agttatttcc atttgttcat ctataacttt tacctcatcc acatttttta taaaatctgc
    52381 tcttggtata tttataattt cttctctttc aaattttaga tttttactta ttatatctac
    52441 aactttatct tcatcaaaat taccttctac aactatatct ataggtgatg ttttaagtat
    52501 gtttttataa tgttcatata actctcttga agttatacta tctatttcat cttcataacc
    52561 aaattcactt acactatatc tctctccttt acacatagcc tcaatacatt tatcttgcgc
    52621 atattccttt ttatcattta ttattgattg tatcttttct cttaaattct ctttttcaat
    52681 atttaaatat tcttctttaa acccaccatc tacaacaagc gtattattta ttacttcatt
    52741 aaaaaattct actacttctt caaatatact ctcatctaaa tacttttcac ttatgttaat
    52801 tactttaaaa ctcaatactt gacgttctcc acgttttaca gcatcagctc ccatagatga
    52861 accatataaa tcatctaatt tattggatat tgctctagca ctaggatatt tagcgcttcc
    52921 acttgctatt attgatggta ttagagcatt ttttgtagtt tctttttcat ccaatagtct
    52981 ctgaacatat aaacttataa gattcgattt aaacttttct gtttttatca aagtaagatt
    53041 aatattatta cctaaattta ttattttttt agtattaacc atatgtacct cctattttta
    53101 tttaaacatc aattttaaaa ttgaaattta tttatttttt aattatatat actcacatat
    53161 aaaaaccttc tatttaatta tatccttttt attattttct aaaagcaata tttttattta
    53221 aattaaatac aaatattatt taaatcaata tgctttaaag tctagtttac aagcttgata
    53281 tatatgatgt ataatcaata tgtatgtcta taattaaaac aattttgcaa tcctatagat
    53341 tgattgttta aagttatata aagaatataa aaaagaataa gagagaggac gattaatatg
    53401 aaattaggta tagttggttt gccaaatgta ggtaaaagca cactatttaa cgcaataact
    53461 caagcaggtg cagaatctgc aaattaccct ttttgtacaa tagacccaaa tgtgggagtt
    53521 gtatctgttc cagatgaaag attaaacaaa ctacaagaat tatataattc tgaaaaaata
    53581 gttcctactg ctatagaatt ttgtgatata gcaggtttag ttagaggtgc ttctaaagga
    53641 gaaggtttag gaaataaatt cttatcacat ataagagaag ttgatgcaat agttcatgtt
    53701 gttagatgtt ttgaggatga aaatgttgta catgtagatg gctctgtaga cccacttcgc
    53761 gatatagaaa ctataaactt agaattaatt ttctcagata tagagattct tgaaagaaga
    53821 attaataaaa ctcaaaaagc tgctaaggct gataaaactt taggttctga acttgattta
    53881 ttaaaatcaa taatgtctac tttagaagaa agtaagtgtg taagaactat ggaatttaca
    53941 gaagatgaac aaacattcgt aaattcattg gatttactta catctaagcc tgtaatatat
    54001 gcttcaaatg tatcagaaga tgatttagct gataatggag aaaataataa atatgttcaa
    54061 caagttaaag catttgcaga aacagaagat gccgaagttg ttgtagtatg tgcacaaata
    54121 gaagcagaaa tttctgaact tgattctgct gaagaaaaga aagagttttt agaaacatta
    54181 ggtcttgaac aatcagggct tgataagctt ataaaatctt cttatgcttt acttggttta
    54241 atttcattct taactgctgg tccaaaagaa gttagagcat ggactataaa agttggaagt
    54301 aaagctcctc aggcaggagg aaaaatacat tctgatatag aaagaggatt tatcagagca
    54361 gaaacaatat cctttaatga tttggttgag catggtacta tggctgctgc taaagaaaaa
    54421 gggttggtta aattagaagg taaagaatac atagttaaag atggagatgt aatattattt
    54481 agatttaatg tttaaaatga ttaatcgtat acactttgac tattatatat aataactaaa
    54541 aaact
//
LOCUS       DACTZW010000019        54446 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.019, whole genome shotgun sequence.
ACCESSION   DACTZW010000019 DACTZW010000000
VERSION     DACTZW010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 54446)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54446)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54446
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.019"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            <1..1568
                     /locus_tag="JAM15_06005"
     CDS             <1..1568
                     /locus_tag="JAM15_06005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAT6797810.1"
                     /translation="VNLNSNLYDDVDRVEYIIRKILTLSNEEKNTIKLEDLADSMYVS
                     VSTVKNDLKEVKRMLEKYSISVKSKHKQGICVLESEDKILNCIVDLSNKRDNQLSLND
                     FLNDDIKERKLLIKKLLLDILNENGLVLTDIEFKSVLNNILVMLSRHKYNEKEFIENY
                     IENYRSKRSSILENEQNKEIIINSIKTFCKNLKLATSIDISNDKVFEEFLYKHISSLC
                     KKIKLGINQSPIMAQDIKIKYPFAFELANIAKKTIEKDLKIEINEDEVANIALHIGGA
                     VERASYNNKDKVFKTIIVCTSGIGTSMLIKAKLENIFKEKLEILKIIPSYLVEYIKVI
                     DVDFVISTVPIEVGDVPVINISPILSEKEIRLIEKYIETGNIYLDLDIKSLFDSELFF
                     TDLVFKRKEEVIDFMASKLVQKGYIDEDMKKSYFEREKIATTEIGNMVTIPHGAIGKI
                     FDNKIAIGILKKPISWEISDVRLIIMLALDKDKILDYEVIFSKIYKRVDSIAKVISIC
                     ENSSFEKFVNLFN"
     gene            1735..2652
                     /gene="pfkB"
                     /locus_tag="JAM15_06010"
     CDS             1735..2652
                     /gene="pfkB"
                     /locus_tag="JAM15_06010"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HAT6797811.1"
                     /translation="MIYTVTLNPSIDYIVKLDELKTGSTNRVKEEYVYPGGKGINVSR
                     ILKELGNDNTSLGFISGFTGEYIIRTLEEKELKTDFIKIKSGFSRINVKIKALKETEI
                     NGQGPNIDDEDIDTLYKKLDKLNQDDILILAGSIPSTLDEKLYENIMARLEKKNIKVV
                     VDATKNLLLNVLKYKPFLIKPNNDELEELFGVKLNSIEDMIKYAKRLKEMGAINVLVS
                     MGKDGALLITEEDEVLISDVPKGKVKNSVGAGDSMVAGFISGYLNTGKYDYALKLGAA
                     SGSATAFSYDLAKREYIDKLVNEISVKQF"
     gene            2689..4608
                     /locus_tag="JAM15_06015"
     CDS             2689..4608
                     /locus_tag="JAM15_06015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005806477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAT6797812.1"
                     /translation="MKIIDLLDEKSIKLNLNSKTKSEAIEELVDLVANSGNLNDKENY
                     KKAILAREEMSTTGIGEGVAIPHAKNSSVTKACIAAAVSKEGIDYESFDGSLSNLFFM
                     IAAPDGANNTHLEVLSRLSTILMDEDFRNKLINSSSEKEFKEIIDKKEREKFSEEYQD
                     EKVAEKNIIDTKENDANKYPKVLAVTACPTGIAHTFMAAESLNKMAENKGVSIKVETN
                     GSAGVKNKLTKDEIENATCIIVAADKNVEMARFNGKKVIKTKVADGIHKAEELIDKAV
                     NGDAPIYHGGDGSHNESNEESESGFRKVYKHLMNGVSNMLPFVIGGGILIAIAFLLDD
                     YTINPSNFGSNTPIAAFLKGIGDKAFGFMLPVLAGYIAYSISDRPAFVVGFVGGALAG
                     DGGSGFLGALLAGFIAGYLVEGLKKIFSALPASLEGIKPVLLYPLLGTLLMGIIMTFL
                     VIPPVTAINNAMVGFLNGLGGTSKIVLGLVLGGMMAVDMGGPVNKAAYVFGVASLESG
                     QFEIMAAVMAGGMVPPLAIALATTFFKNRFTKEERDSGKVNYVMGLSFVTEGAIPFAA
                     GDPLHVIPACVGGSAVAGALSMLFNVALRAPHGGVFVIPVVTHPFAYILAIAVGALVG
                     MMLLALLKKPLNQEV"
     gene            5203..6729
                     /locus_tag="JAM15_06020"
     CDS             5203..6729
                     /locus_tag="JAM15_06020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAT6797813.1"
                     /translation="MNESYWFLNSSPKEYNKLGENIKTDCLIVGGGITGLTTAYLLAK
                     EGKKVVLVEADKIGYGTSGRNTGKVTCQHDIFYSKIEKKYGLDKAKSYYNANNEALNL
                     VEQIIEENNIKCDFKRETSFVFTEKEDTIKNIKDEYRTCKKIGINCEYHETIENIPLD
                     IKGAISFTNQGQFNPKKYIDGLAKAAVNLGLKIYENTPVVDLEKGKICRVKTREDNII
                     EAENVIISSHSPWYDGLNFYFAKEYAERAYLMVAVLENKLADGMFISIDDPSITFRQY
                     NDGSENLLIFGGGDHKVGQGGTEKEIFDDLEHYGKEVFKVKDFKGKWSAQDNMSFDNV
                     PYIGYINKREDNIYVATGFSKWGITNGTAAGIIIKDLIINNNSDYKDTFNPSRLGSYF
                     SKDFIKENANVAINYVSGKLKIGSGDMPKNNGEGKIVNIDGKRYGVYKDDNGDFYIVD
                     TTCTHLGCELNFNSEEKTWDCPCHGSRFDYKGNILEGPALKPLKLYGHGDNDVNPKLL
                     "
     gene            6757..7314
                     /locus_tag="JAM15_06025"
     CDS             6757..7314
                     /locus_tag="JAM15_06025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797814.1"
                     /translation="MNKLLKPITILLYIVYILSAVFFVANKEYGSLGLVAISLVGTFI
                     LSFINKQTERLLSKELYIMLALFIMFSSLLGTCFNFYDINYYDDFLHLWSGIISCIVA
                     FSIIKYFYTQREISKMSKVFLVIFLFMFSMGVASLWEIGEFLMDTFVGTTTQAGGLED
                     TMIDMVDALIGTIITIPFIVKKSNI"
     gene            7836..8879
                     /locus_tag="JAM15_06030"
     CDS             7836..8879
                     /locus_tag="JAM15_06030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797815.1"
                     /translation="MLKKWFGIVKKRQKSESVKEEGEVILKNEKILSEEKLIDEEGVV
                     VNIDNEILTKVEVVNDDNEIEEKIIEEDWLISENTIKLDDKEAIINDKNIELCKKEVQ
                     VESEKIGLNKFEGLDQNENYNLEKNVIEEKKVSECLTEEDLEYIKEIKIKRGKSIKAI
                     NLYTKEEWVFDTHIQCSKKLKVPLGYIRENLKYGYMDYFGDAINYLSEVLNIDEYCKS
                     EWSYLDNSKSPSEIFNILNNKIFSIRLSNEKRNEILTNDKIEALKMNYRFECIDEEYD
                     EYFKKYKSIIKRGGKKKVELVNKKGDILEIFKSLEECAIYLQKEKNEVIQMLKYGDTK
                     VGRNFIRYSLRSI"
     gene            8990..10132
                     /locus_tag="JAM15_06035"
     CDS             8990..10132
                     /locus_tag="JAM15_06035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAT6797816.1"
                     /translation="MSEEKNPKENTLDEPKNSDNVNSKKDDVSDEKNTDNKVKKREIK
                     LNNKTLKAIVAIVAVGAICLGGGYVFGKEAGRKLPATSKHYNSSEVVATIGDKKITGE
                     MLRKRMEPLFYLNAKTTMTDDEIRSYESNMIETMITSDILSSEAAKEKISITNDQLDA
                     QYNNLMSSIESAMGMTKEEFLKQFDLTEKYIKDDMKKELVASKYLNEKSKVTDKEAEN
                     YYNKNKSNYLQVRASHILIKTVDDKGKQVSSSKKAELKKEAEEILKKAQAGEDFATLA
                     KKYSEDSSAESGGDLGFFGKGQMVESFEKAAFALKKGEVSNKLVESDYGYHIIKKTDE
                     KYQPFEEVKSDLVSSLTSEKQNLLIQNLKEKYNVKITDKYQMKAKE"
     gene            10586..11977
                     /locus_tag="JAM15_06040"
     CDS             10586..11977
                     /locus_tag="JAM15_06040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HAT6797817.1"
                     /translation="MSSTESVSKKSGHPKSFWLICMTILWERFSYYGLTALLVLFFTA
                     SVAQGGLGLSTQEATSMFGLFTGLIYLTPLVGGWLADKVLGQQKCISIGALLIAIGDF
                     VLFASSTSIAMVWVGLSIIILGNGFFKSSCSNIVGDIYPKTDVSRKDAAYSLFYMAVN
                     VGAFIAPIICGLLSDNVFAVRGASGDIVSYGYKMAFLICGIGMMLGMIIFTLLAPKLL
                     NEVGKYPVTKGNKGEKIEYGPLTKLEKNRIIAMVILFLFVVLFWTAYYQTQSSFMIYV
                     RDNVNRTLFGFEMPVAWLTSLNAILCVALCPVLATLWVKLSHTKRGDFSIPVKMGLGM
                     IIMGVGFIVMVFATLANGPDGMVKASILFIVLTYIFTTVGELFLSPIGLAMFNKLAPA
                     KYATLSMGAWYLTSFFASLLSGKIAGFTATLGFLQIFGGIATVLIIFGLILLGIRNVL
                     TRLMAMDLLTKEK"
     gene            12230..14023
                     /locus_tag="JAM15_06045"
     CDS             12230..14023
                     /locus_tag="JAM15_06045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016440642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HAT6797818.1"
                     /translation="MNIKDRLSGLRKFMEEKNIDAYMIPSSDNHQSEYVGDYFKSREF
                     ISGFNGSAGTVIVTKDEAGLWTDGRYFIQAESQLEGSTIKLFKMGQEGCPTTDEYLYK
                     NIPEGGTLGFDGRVISAREGATLAEKLSKKGIKIEYQYDLIDGIWPDRPALSDSKAFL
                     LDVKYCGESFSSKLARLREKMSEKGTSTHVITTLDDIAWLFNIRGGDVKYNPVVLSYA
                     VITLKEVYLFVDESKLNEEILDELAKENVQIKPYNDVYEFVKNIDKTEKVLLDGTKLS
                     YTIYNNIPCEVEKVDEFNPVMFFKAQKNEVELENIRNSHVKDGVAFTKFMYWLKKNVG
                     KMEITEISATQKLEDLRREQEGFFEPSFNTIAAYKEHAAMMHYSATPESNYKLEAEGL
                     FLVDSGGQYYDGTTDITRTTVLGPISDELKLHFTSVARGMINLSKAKFLHGCRGYNLD
                     ILSRSCMWNMGIDYQCGTGHGIGFVLNVHEAPNGFRWRVVPERFDSAVLEEGMVTTNE
                     PGIYIEGSHGIRTENEIVVRKAEKNFYGQFMEFEVVTLAPIDLDGIVPELMNKDEKDY
                     LNWYHKLVYDKISPFLTDEEREWLKVYTRAI"
     gene            complement(14104..15486)
                     /locus_tag="JAM15_06050"
     CDS             complement(14104..15486)
                     /locus_tag="JAM15_06050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HAT6797819.1"
                     /translation="MSVLKTQEKLKQPRDLYFCCSIFTFVGLAYYGMKLVLLLFLAEQ
                     VSKGGLGLTPAESASMLASFLAWTYFSPVIGGWVSDRFLGPKNCIILGMLMVSIGYFL
                     GYIANSKMDINIMIFLSGLGIGFYKGNLHTMVGNLYTNDDPRKDGAFSITYMATNLGT
                     LFGPLICGLVANEWFAMKSGLSISMYGYRYVFLFSSITVLIGLFFFIFGNRKFYKPLN
                     NDPSNGRESIRKSLEYKKMLASRPLTLIEKKRIIVILVLAFFTVFFWIAYNQASMSIA
                     LYTKEHINLTVGNFQIPTSWIDSYNGLLCVILGPISALVWVKLSQTKKGDLSVPKKMS
                     LGFILLAIAFLFMIVAVIQTGTDPNSIHKASVFWVVGFLTFQSIGEICFSPVGYGMVN
                     KLSPEKYISFLMGVWFLGKFAANKLSGYTQAIIDQLGMLQVFIVIPSFLLIFGIILLI
                     MNKKLVELSN"
     gene            15744..16091
                     /locus_tag="JAM15_06055"
     CDS             15744..16091
                     /locus_tag="JAM15_06055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HAT6797820.1"
                     /translation="MIRKKSELQVEVKENLNGGIGKVKLENIIQNEELKGKGRLFKRV
                     ALPVGSSIGVHDHTTDFEVYYILKGKGKVFDNGEFVEVNEGDVVYTADGEKHSIENIG
                     EEDLEFVALVLYM"
     gene            16109..17143
                     /locus_tag="JAM15_06060"
     CDS             16109..17143
                     /locus_tag="JAM15_06060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797821.1"
                     /translation="MTGKIEEIKDKINRFCNSNLNQEYKDISFKILQNLLDNNKEIIH
                     SSRADIWSSAILNIVLEQNLLYNKKHPLHITKKEFSKQIGVSLNTINNKSSLIKDVCS
                     IDFLNQDTIAISNVEFWVKETNSKSKSVDLDLEKKKILYKRYIKLSQDANSDIESIRY
                     MEEAVNIGKSMITKEDKELGFWKGLSTRAYMIALESLARKLESINNLKESKKVLEYLI
                     EINPSDEQGIRYKLLNVLIRLNDRTSINKLFELYKEEKSATWMYSKALYYFKNKSMFL
                     ANDSIKVARSKNKYVGLYLLDWRNAFGREFVTEEEKAEAVYYYDENIVIWNEVKGSMD
                     WLLKKMLEFS"
     gene            complement(17192..18241)
                     /locus_tag="JAM15_06065"
     CDS             complement(17192..18241)
                     /locus_tag="JAM15_06065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAT6797822.1"
                     /translation="MEINYKKRNFKSFAKRKNIEISVQRYLIDALSYMALGLFSSLLI
                     GTIFNTLGDNFNISLFTEVISPLAKQVTGPAIAVAIAYGLQAPPLVLFSCALVGACGN
                     ELGGPVGAFVATLFAVEVGKLVSKETKIDILVTPAVTILIGVLVAELIGPAVSAFMTS
                     FGNIIMQATTMQPIIMGALVSALVGIALTLPISSAAICMMLSLGGLAGGAATVGCCCQ
                     MVGFAVMSFRENGVGGLVAQGLGTSMLQVPNIIKNWKIWIPPTVASILLGPLSTTIFK
                     MENIPIGSGMGTCGLVGQFGTVTAMQSAGKGGISMWVGILLLNFILPAIVTLLISEFM
                     RKKGLIKPEDLKLDV"
     gene            18516..20051
                     /locus_tag="JAM15_06070"
     CDS             18516..20051
                     /locus_tag="JAM15_06070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797823.1"
                     /translation="MIFVKNKKYRKIAIIISIPILLVAQYYLFKFGILRPMVKGVEIE
                     IVDGEYVKDIDKYVVKLNETVTLSTGEYIKVPSYAKNPNIWFNVLDNSGTLKIDGNKM
                     TALKVGYSSVGIMKNSRVLKKATIKVVDPEVESLDMEINGDLKHVGDSATIESTIEVD
                     YDKFKKSYKPVYKSSNENILKIKGNKVSAVGVGKATIYAKCGNKEIERTFRIQARVAE
                     INMDDIKIEVDQNEKLKPDIITSPPGLEPPKIYYELVDSKLPVERAISLSSNGNVVGL
                     REGKDRVRITCGDKSKVITVTVVKETITNDYIQNLVGSHKIVNNKVIIKLEWDYMKDV
                     FDYDIYLKDKLSGESFKKIKSITINESDLGKSNKVYATIEVDMKGNQNIDFDIYVIGK
                     KDSDTTKPSNVINITNGNGNSNNDNNIKDMRVENISANVDRDNNVIRVNWSSISHKDC
                     TYSIYVKNNTNGDGEFTLYQSDIQGNEHTISIPEGDLNLDIYVVANYNGNSSQNSDVI
                     NVR"
     gene            complement(20237..20923)
                     /locus_tag="JAM15_06075"
     CDS             complement(20237..20923)
                     /locus_tag="JAM15_06075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008699189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate/glutamate racemase family protein"
                     /protein_id="HAT6797824.1"
                     /translation="MKTIGLIGGMSWESTITYYQVINTVIKERLGGLHSSKCILYSVD
                     FQEIEECQSSGNWEKSAKILADAAIKLQEAGADFIVICTNTMHKVSDKIQESIHIPLL
                     HIADVTATVLREKEIKKVALLGTKYTMEQDFYKNVIINNGIEVLIPNEEDRIIVNDTI
                     FNELCLGIISESSKKAFLSIIDKLGKQGAEAVILGCTEIGLLIKQNDTSIPLFDTTVI
                     HAIEAALSSI"
     gene            21048..22430
                     /locus_tag="JAM15_06080"
     CDS             21048..22430
                     /locus_tag="JAM15_06080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAT6797825.1"
                     /translation="MPINSFENYPMTWKPKLDNRKPPIYKTLAMLLEEDIKRGNLNPG
                     DKLPPQRELADFLDLNLSTITRAFKLCEEKGLICAKVGKGTFISSDVNVSNTLLYQTE
                     SKDIIELGTVHPPYEQNTYIIDFIKNVLKQPEMDRFLQYMSPSGTYMQKKSIAKWIER
                     NNVYTSEENILLSTGGQNAICATLLGLFKAGDRIATDSLSFSGIKSIAKMIGIQLVPI
                     PQENNEISIEYLESYCKNENIKGIYLIPDYHNPTTHTMSDLSRKKIAKIAKQYNIIII
                     EDAINSIFRDGIQTPIFSLASDNTIYIFSTSKFLCAGLRVAFVVAPKRYIENLENALY
                     NMNLMVSPFTAEIVHRLLYSPIIDKIIEEKRDAIIERNEVADKVLSDYNLIGDKNCSF
                     RWLLLPDELDGKSFEISAKNLGVQVYCAERFSVGNSTVPKAVRICVTAPKDVEELEKG
                     LNIIKSLLKS"
     gene            22832..24100
                     /gene="eam"
                     /locus_tag="JAM15_06085"
     CDS             22832..24100
                     /gene="eam"
                     /locus_tag="JAM15_06085"
                     /EC_number="5.4.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 2,3-aminomutase"
                     /protein_id="HAT6797826.1"
                     /translation="MNEQTRISLERAAELKSKIDDYIQARKTINRGLEKEEEINKRKQ
                     KILSILNGTEEDWNNYKWQLSNRITDVDTLSKIITLTKKEKEYIKEVGTQFRWAISPY
                     YLSLIDPEDICDPIKLLSIPTHIELEDEQEDLDPMGEEYTNPAGCITRRYPDRLIINV
                     TNECAMYCRHCQRRRNIGQQDSHKSKAIIQESIDYIRENEEIRDVLVTGGDALTLKDD
                     YLEWILSQLKEIPHVDYVRLGTRTLVTMPQRITDEFCNMLKKYHPVYINTHFNHPMEI
                     TKESKEACEKLANAGVPLGNQAVLLNGINNDKFVMRCLNQELLKIRVKPYYIFQSKHV
                     KGTKHFNTSVDDGLEIMEYLRGYTSGMAIPTYIVNAPKGGGKTPLLPQYLVSKGTDYV
                     MLRTWEGKVIKMEDEPAVDIKKLIKEQAQD"
     gene            complement(24193..24549)
                     /locus_tag="JAM15_06090"
     CDS             complement(24193..24549)
                     /locus_tag="JAM15_06090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797827.1"
                     /translation="MKKALISLLVLSCLLLTAPVNESSYADSQKNVPVSQNTKLTQEQ
                     AKELLVKYNNEVDYIYQGNASDFEALKAKNLNGYVFLPDADGDIGYFVNENTSEIYYF
                     HPSGYLELVNQQQNNK"
     gene            complement(24700..25794)
                     /locus_tag="JAM15_06095"
     CDS             complement(24700..25794)
                     /locus_tag="JAM15_06095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAT6797828.1"
                     /translation="MQDKKIYLNIVLTVVVSYILIKVIDNYKYFFGVISLLMSLLTPF
                     IIAFVLAYIFNPLVKFLESKLNFKRIYSLLLTYGVLIVILISFILFTVPSIVNSLADL
                     VAQIPTYIDKTEQFLFDLGKSLQSVDPNTLKEYGDKIMSVMPKFSNLLIGSLGGIFST
                     TFSVGKFIVQFLLGFIICFYILLEKEKFLLFTKKVVYISLGKKYGDFIIELCQSLNLN
                     IGKYFTGKILDSFIVGVLSGIGLYFLKSEYALLFGTLMGVMNMVPYFGPVIGMAPVVI
                     INLFSNPTIALTSLIYLIIIQQVEVTFIEPKIVGGQLGLSPFFTILAVTVGGGFFGIP
                     GMILSAPVMGVIKIYFCEFVNRRHDKIQME"
     gene            26258..27079
                     /locus_tag="JAM15_06100"
     CDS             26258..27079
                     /locus_tag="JAM15_06100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HAT6797829.1"
                     /translation="MIKKEISNFRGSSDYVVSPELMASVNVAIALEKPLLIKGEPGTG
                     KTMLAQAISNELKKDLVIWNIKSTTKAQEGLYVYDTVQRLYDSQFGGEGVDDISKYIK
                     YGKLGEAFSSNQQVILLIDEIDKADLEFPNDLLWELDKMEFYINETKETVRAKQRPIV
                     IITSNAEKELPDAFLRRCIFHYIEFPDRDMMEEIVKVHFDKVEEHLLEQVMTTFYWIR
                     SLKDIQKKPSTSELIDWIQALTLSGMPIEKIEKEVPFAGILLKNNEDIESMQRHL"
     gene            27100..28296
                     /locus_tag="JAM15_06105"
     CDS             27100..28296
                     /locus_tag="JAM15_06105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HAT6797830.1"
                     /translation="MFIEFFYLLRSRGLNISLNEWMTLIEALDKGLCYSNFSNFYYLC
                     RMILIKSESDFDKFDAVFLEYFKGIEHQEEIPEEIMNWLKKPDIDLEEFERLEQNPNI
                     NLDKLRAKLEERIKEQDSPHNGGNYWIGTGGTSELGHSGKGQTGIRIGGNSTYGRAVL
                     EVAGERKYRDFRDDEVLNMRQFQVALKRLRQFSTRIDAPKTELDLDKTIEETCNNAGY
                     LKLFFEKPRKNTVKLLLLMDSGGSMRGYSTLCNTLFQSVSKSNHFKDVKIYYFHNCIY
                     DRLFTTPECWLSKSINTEWILKNIDKNYKVIIVGDASMSPSELLHIGGNYRGPYNYTP
                     GIEWLKRFKRKYSKIVWMNPELRDGWDSINYWYQTQRMIQSEFNMFPLTVKGLEKALK
                     NLMLSR"
     gene            28462..31860
                     /locus_tag="JAM15_06110"
     CDS             28462..31860
                     /locus_tag="JAM15_06110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HAT6797831.1"
                     /translation="MIIINYELIVKYNGDILRLEEELGVSVEILNSSYAIITSSNEED
                     VNTLLTYPEIEFIEKPFILQTQDVQSFSSTGITGFKNRTGLTGKGTIIGIIDSGIDYT
                     LPVFRDSDGRSKILYYWDQSIQGNPPEGFREGTLYTNEDINNAIDGSMYIPISTTSLH
                     GTHVAGICATIASDARIIVVRVGNIQTDIFSRSTEFMRAIKFILDRALELRMPVTLNI
                     SYGSNEGSHRGTSLFEQYIDDMCLFWKNNIVVAAGNNADKGGHKRIRLQNNITEEVEF
                     IVGEGERILNINIWPDFVDDFSVHLVNPSNNQTQAISLTSGEIRNTLGETRITGYFYP
                     IAPYSLTRRVTLQLSSNTQITPGLWKIVFEPIDIVTGNVNIYLPTSEGLNRNTRFLIP
                     TQELTVTVPGTASRVVTVGSFNSRTDIVSIFSGEGDTQLGVFKPDLLAPGEDIISFLP
                     GGTSGALTGTSMATPHVTGVCSLFMEWGIVNGNDLFLYSQKLRALLLKGARRLSNQSY
                     PNNSSGLGFLNLSDIDLYTLSNINQDLETEDIGYRSINKSFKDEENSYKLIDGYNMQI
                     HNDLENEIYISKNASRQSGILSGIDVVHTPEFEEELAELGMSQSFFKISDSLGVLFIN
                     NTDYSSIQRVLQLSSIIRTVSTTKRTLLGEINRGTFGGVVATEEMGVNFFKNNPNINI
                     TGRGTLISIADTGIDYLHPDFIYPDGTSKIVYLWDQTKEGTPPDGFYIGTEYTREDIN
                     RAIAENDPSLSQDEVGQGTMLSGICAGLGNVNSEYAGIAEDSELIIIKLGKIDGFYNS
                     AMLFAASQYAYKKAFELRRPLVINMSLGTSSLAGLTNRSNSEKAFFTRGLCITAGAGN
                     EGNTQTHTSGIIPHVGGSVEVELELNEDEEELSLELWLNRPDKADVIIVSPTGEESKS
                     VGISNYNKVTGLFDLEGTEYSITYIYPTTFSGQQFTNVTLKNAKRGVWKIRLVGVYII
                     TGRYNLYLPNRELLKSGTRFREVDPFYTINYPAIQDDLITVGAYNTINGSLWQSSSRG
                     PTIEDRLKPDIVAPGVNIIAAYPGNTYATITGTAAASAHAAGAAAMYFQYTFVDGRYP
                     NQAYVQKIKTFMQAGARKDSNTVYPNTNSGYGLLDVRGMFDVLR"
     gene            31870..33543
                     /locus_tag="JAM15_06115"
     CDS             31870..33543
                     /locus_tag="JAM15_06115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HAT6797832.1"
                     /translation="MEKSYCIIYQGDIESALQENGINRYMVLNSQLAVIYVPVDFDET
                     ILNNIIQVAWWEESEPMSSLIEITNNVNNGETITTAAETDYIYENPYNDITGRGILLA
                     VIDSGIDYLHPDFINDDGTSKVLYLWDQEANTNPPPEGFIFGSEFTRSELNIAINRND
                     GSLSQDNIGTGTLVSGILVGNGRINSQYRGITTESDLIVVKLKSYTDTYYAGRINYSV
                     SDFLAAITYVTNIARTENKPLIINLTIGVKSSAVATTSILDTFNILSSAGVVVVSGAG
                     NQGNTDIHYSGRFSSVGEVQDVIIQDGDDYALDITLNTNGPDKVGAQIISPSGEVSHD
                     IRYSPDFYIYRGKFNLENTTYAMRFIYPYITSGKENLEIRLRDIKPGVWILRLTSELI
                     ISGEYDIYLPNKNLIAPDTRFLDPDSVATITMYAASDDVITVGTFNNKTDSMWIGSSK
                     GPIRGRGIKPDIVASGVDIISTYKNGTYNTGTGTGVSSSIVTGVLALLMEYLEKQDNV
                     PRLSLFTQVLKTYLILGATKLEIYTYPNVSQGYGILNLKNTIQQIANTL"
     gene            33817..34011
                     /locus_tag="JAM15_06120"
     CDS             33817..34011
                     /locus_tag="JAM15_06120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3787 domain-containing protein"
                     /protein_id="HAT6797833.1"
                     /translation="MESKKARALKGKDNKRLKSSLLVGNESTAAWADVEKLKPHSKVS
                     IPSIKGVEEAKDWVDNGSKL"
     misc_binding    34180..34413
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            34490..35887
                     /gene="asnS"
                     /locus_tag="JAM15_06125"
     CDS             34490..35887
                     /gene="asnS"
                     /locus_tag="JAM15_06125"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HAT6797834.1"
                     /translation="MQKEFITVKELYREKEQYIGKTVKVAGWIRTSRVSKNFGFIELN
                     DGSFFKNMQIVFDEKVENFKEVGKLAISSSILVEGELVSTEGAKQPVEIHAKSIVVEG
                     ESDSSYPLQKKRHTLEYLRTIAHLRPRSNTFSAVFRVRSIAAYAIHKFFQERNFVYAH
                     SPIITGSDCEGAGEMFRITTMDLNDIPKTEDGKIDYTQDFFGKEANLTVSGQLNAEIM
                     ALSFRNVYTFGPTFRAENSYTGRHASEFWMIEPEIVFADLEDNMELAEDMIKYVISYV
                     LENAPEEMEFFNSFIDKGLLERLNKIVNSEFIRITYTKAVELLIESGHEFEYPVEWGC
                     DLQTEHERYITEQIYNCPVFVTDYPKDIKAFYMRMNEDGKTVRAMDLLVPGVGEIVGG
                     SQREEREDVLLDRINEMGLREEDYWWYLELRKFGTATHSGFGLGFERIIMYMTGMSNI
                     RDVIPFPRTPKNAEF"
     gene            complement(36060..37235)
                     /locus_tag="JAM15_06130"
     CDS             complement(36060..37235)
                     /locus_tag="JAM15_06130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HAT6797835.1"
                     /translation="MNLEKIKKFFGFPLDKKHKENVEKELCNYLYHTGKIICIIIVIS
                     QIIMMISISAREGGPFATPRRQWYFYMYVTLFCVSSVFMFVFSYLWNKKKDCCTFYIN
                     LWIIYVTFFCLWGCVITLLDQLGGNDLSVFSYIILAAAAFSVLKLGESVIVFGGCFLF
                     LNLFLPGIQTIPGNEFSNIVNTFFITSLAIFVSTMLYRNRVFTYYDKLLISQQYEEIS
                     HINNLLNDKVMTDDLTKMNNRRYLEDILQKKLISHANQEPITGMMIDIDYFKQFNDNY
                     GHQKGDYCLQNIAKVILDFTSSENEHAIRYGGEEFFICIFNCNEADAKLKSECLRKII
                     ESCNFERDDVPLKCVTVSIGVYTKKIEKTITLNEFISNCDKALYTAKEKGRNCVAFY"
     gene            37654..39018
                     /locus_tag="JAM15_06135"
     CDS             37654..39018
                     /locus_tag="JAM15_06135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HAT6797836.1"
                     /translation="MGEKKINNMNYSHNNYSKKTGEPTRKIKNSHITLKSKEEKICSS
                     CNKENNTKDNYCKFCGNELYEITSLRPLETKLDLKSKIKELSYHANKRGVFLTTFTTI
                     FILFIIALIFKAIITIQFNDISYLINPAHIILALNLGQISVSMSTMMGSGFINANIGL
                     LILLIIPILVLLISNLIFMRKRCRDSKTVLANSLGVGIFYGLVLAILSIFTNVKTSSH
                     SMLEYGYALEYSYEFFSVLLNGFVLGFICTYITTYKKSYEKENMYLSLFSNSIRTFIL
                     GYILVLVILLVLTISDSSYLNELDMSSYSNGLNLFTILPQIASYMWAFANGISVTIIN
                     STVSMFTLSSSSLFGDTKLMFYAMGALSMLILLLNGYKLRFKYNTDSIKPIIVFSIYY
                     AFLMGMLALFSTFILDSNINFFNTTSYGATLIMQFKVLQAIVISFVYSFVISLIGYKL
                     NSAD"
     gene            39040..39531
                     /locus_tag="JAM15_06140"
     CDS             39040..39531
                     /locus_tag="JAM15_06140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HAT6797837.1"
                     /translation="MEGNTNNKVDDKFSKVKKKFGSGKFKVELYKEKSKLNREIDDIQ
                     EKKAKIFLEMGILTYQKIREDSINDNSFDKFCDELLELDKLIYEKNMEINEMEMAESS
                     VTCECGYVGNVNDKYCAECGKKFELENECDDFIVCGYCESEIDIEAEFCPCCGRKIIM
                     DLE"
     gene            39804..40475
                     /locus_tag="JAM15_06145"
     CDS             39804..40475
                     /locus_tag="JAM15_06145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HAT6797838.1"
                     /translation="MLDKVKGRLIVSCQALENEPLHSPFIMGRMAKAAMEGGAVGIRA
                     QGVEDIIEIKKVTGLPVIGIIKRNYEDSDIYITPTKKEVDELLTTGCEMIALDATNRV
                     RPNNEDLKELIKYIKENGVLVMADISNYDEAIKAQEYGVDCVSTTLSGYTPYTKTLEG
                     PDFVLMERLVKDLEIPVIAEGKVNTPQDLKKVFELGVHSSVVGSAITRPQLITEKFVK
                     AIEIN"
     gene            40560..41426
                     /locus_tag="JAM15_06150"
     CDS             40560..41426
                     /locus_tag="JAM15_06150"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HAT6797839.1"
                     /translation="MKGIYSALLVSFDKEGNINEKGLRQIIRHNIDVCKVDGLYVGGS
                     TGENFMLSTDEKKRIFEIAKDEVKEEIKLIAQVGSVNLKEAVELAKFTTDLGYDAISA
                     VTPFYYKFDFEEIKHYYNTIINSVDNRLIIYSIPFLTGVDMSLDQFGELFENEKIIGV
                     KFTAADFYLLERMRKTFPNKLIFAGFDEMMLPATVLGVDGAIGSTFNVNGVRARQIFE
                     LTKNEKISEALEVQHVTNDLITDILGNGLYQTIKLLLEEQGVEAGYCRQPMKEATDEM
                     KSRAKEIYRKYF"
     gene            41459..42961
                     /locus_tag="JAM15_06155"
     CDS             41459..42961
                     /locus_tag="JAM15_06155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HAT6797840.1"
                     /translation="MVGFTWIDFAILVVYLLAVLFAGLLFSKKEMKGKEFFKGDGTIP
                     WWVTSVSIFATLLSPISFLSLAGNSYGGTWILWFAQLGMFIAIPLTIKFFLPLYSRLE
                     IDTAYEYLEMRYESKGLRILGALMFIIYQIGRMSIIMYLPSVVLAGLTGIPVNVLIVV
                     MGVIAIIYSYTGGLKAVLWTDFIQGMVLIVGVTGTLFYLIASINGGFGTVMDTLTTGH
                     KFLASNEVMFDKNILSTSAFIIFVGAGLNTFSSYVSSQDIVQRFTTTTDIKQLNKMTY
                     GNGVLSMGLATVFYLIGTCLFIYYTQNPDLAQTVQQDQVFASYIAYELPVGITGILLA
                     AIYAASQSTLSTGLNSVATSWTLDIQTIITKDISMEKQTKIAQYISLGVGILSIAVAI
                     VLANGEIKSAYEWFNSFMGLVLGVLAGIFVLGAFCKKATKIGAYVGFIVSAILVVYLK
                     YRMPEVTSWAYSLITITTSVVVGTIVSAIEAKVKAKVSLPKAETTVYYEK"
     gene            43091..43543
                     /locus_tag="JAM15_06160"
     CDS             43091..43543
                     /locus_tag="JAM15_06160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF386 domain-containing protein"
                     /protein_id="HAT6797841.1"
                     /translation="MIFGNINHSKTYSTLHEDLLRCFEYAKDNSLIDYEKGTYTIDGD
                     DIFVNIVEYKTCEKEDRFWEAHKKYIDVHLMLDGCERIDINFIENLEQKIYEEEGDFL
                     PLDGKNNGYVELKKGDFLVCYPEDAHMTGIKVLEKENIKKAIFKVLVR"
     gene            43703..44506
                     /locus_tag="JAM15_06165"
     CDS             43703..44506
                     /locus_tag="JAM15_06165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sialate O-acetylesterase"
                     /protein_id="HAT6797842.1"
                     /translation="MENIDVFLLIGQSNARGLGNPKESVIPNENCFEYLSTDEIINMR
                     CELETSEGDGTIAPAFSNEWNKLTGNKVCFIHNAKDGSRIKNWNHDNNWFLNNTIEKF
                     NAGCTTLSKHYNIENKYVIWIQGESDAKYGSDALYYKESLKKIAYRLKEECMIDKMFV
                     SLTGYWLGEDEYFIRTRRIAAAQESACSECDILCVGSKIAMQFHDRGLTIDDVHYTQE
                     GLNILGKDLCENIYKYHTTKEKELLSDTIDLSEARRYIYELEKISKKFV"
     gene            44564..45451
                     /locus_tag="JAM15_06170"
     CDS             44564..45451
                     /locus_tag="JAM15_06170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAT6797843.1"
                     /translation="MKNYVCIDVGGTSIKYGFIREDGLIIDKSSLDTEAKEKGGEGIL
                     SKIKDIVKKYIKENEISGVCISTAGMVDPVEGKILFALEELIPNYKGMQLKKEVEKEF
                     NIKCEVENDVNCAGLGEMWLGAGRGATSSICLTIGTGIGGCIIINNKLINGFSNSAGE
                     VGYMNINGSSFQELASTSSLIKKVAKIKNLNEKDLNGKIIFDLAKNNDEDCLKELDNM
                     IKSLAVGIANICYVINPEVVILGGGIMAQEKFLKPKIDKALKEVLIERVYKNTNIEFA
                     KRQNDAGMLGALYNFLNKI"
     gene            45470..46318
                     /locus_tag="JAM15_06175"
     CDS             45470..46318
                     /locus_tag="JAM15_06175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAT6797844.1"
                     /translation="MSILEQLESPTFKVTKSDKLLIAYIKENIDDVFYKPISQIAKES
                     NIGEATITRFVKKMNFNGLQDFKVTLAQEISTINKKNIINKNIQNDEPALDTAKKLLS
                     SNVTTLENTVEIINSKDVHDCARLIINAKKVYFIGIGYSGIIAQDSNYKFMRIGLNCV
                     SFDSSHTMIMMSSIMEEGDLIIAISHSGETEEIIKTVKLARANNAKIISITENKNSEL
                     KDISDVHLSYVSGETVLETGSISSKLAQFFIIDLVYTQVVKELSNEAIERKIKTTNAI
                     KLFKNE"
     gene            46381..47070
                     /locus_tag="JAM15_06180"
     CDS             46381..47070
                     /locus_tag="JAM15_06180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAT6797845.1"
                     /translation="MSKLKDYNIDKVIIFNNLSTKTKNQLKEKAKLKRLQKKEILFYE
                     KDSLDSVYILLEGKVSIFKISENGERKVIFILNSGEVINDITFDSSKNSTVGCEAFEN
                     SIVAYYSIEEFLEIMQNDFQLTKDIISYMERRIRRLYRQLKNSISIKVDKKLAAKLYR
                     LSREFGVCCGEWTLLNVNITVTYLADMLGCKRETVSRMIKVLQKEELIKIDNKGFYVK
                     ETELSRYFKNN"
     gene            47461..48468
                     /gene="asrA"
                     /locus_tag="JAM15_06185"
     CDS             47461..48468
                     /gene="asrA"
                     /locus_tag="JAM15_06185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrA"
                     /protein_id="HAT6797846.1"
                     /translation="MKLKLDSSKFNEGLNYLKKDYKIFAPVLIPFKGTFSDTDVIRYK
                     EVNAFEEMEFAKKANFSPKEVVLPINQVLFYFTEKEFKESDLDNKKILIFLRACDING
                     IKRLDEIYLNNGEEKDYFYKNIRDKVKFALVGCKESFRNCFCVSMDSNKTDNYSIGLN
                     IEGDTLYLDIKDSEFEVFNGEATEFNVDYVTDNLISVDVPENIDSNEIIGNSIWDEYD
                     TRCIGCGRCNFVCPTCSCFTMQDIFYKENENVGERRRVWASCQVDGYTDIAGGNSFRK
                     KQGERMRFKTMHKIHDFKKRFGYHMCVGCGRCDDACPQYISFSKCIEKINDLVTSKEE
                     V"
     gene            48469..49260
                     /gene="asrB"
                     /locus_tag="JAM15_06190"
     CDS             48469..49260
                     /gene="asrB"
                     /locus_tag="JAM15_06190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrB"
                     /protein_id="HAT6797847.1"
                     /translation="MNPYIPVSAKILDIVKHTDKEWTFRVNCDTKGVLPGKFYEISIP
                     KYGESPISVSGYGEDYIDFTIRNVGKVTSELFNYKEGDSFFIRGPYGNGFDVSLYEGK
                     EIVVVAGGSALAPVRGIVEYFYNNKEKCEKFKLIVGFKSPKDILFADDLKRWSKKLDI
                     LVTVDGAEEGYCGNVGLVTKYIPELDMKDINNTSIVVVGPPMMMKFTVEEFLKRDLDE
                     KNIWVSYERKMCCGIGKCGHCKMDDTYICLDGPVFDYSYAKNLID"
     gene            49273..50244
                     /gene="asrC"
                     /locus_tag="JAM15_06195"
     CDS             49273..50244
                     /gene="asrC"
                     /locus_tag="JAM15_06195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite reductase subunit C"
                     /protein_id="HAT6797848.1"
                     /translation="MIRDLNTKKVMKNAYRITKTKYETSLRVRVPGGLIDPESLAVVS
                     KIASEYGNGQVHITTRQGFEILGINMEDMEEINKIIQPVIEKMNINQSEKNAGYPAAG
                     TRNIAACIGNKVCPKAQYNTTEFAKRIEKAIFPNDLHFKVALTGCPNDCIKARMNDFG
                     IIGMALPIYEKDRCVNCGACVKKCSKISVGALKTENNKVVRDKDKCIGCGECVLNCPT
                     NAWTRDEKKYYRLAIMGRTGKKNPRLAEDFLLWVDEDSIIKIILNTYRYVEKYIDKDA
                     PGGKEHIGYIIDRTGFMEFKKWALEGVELPEITKMYENIYWSGIKYL"
     gene            50301..51077
                     /locus_tag="JAM15_06200"
     CDS             50301..51077
                     /locus_tag="JAM15_06200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HAT6797849.1"
                     /translation="MHKETLDKLTNAAINKINLLNTSKVKYLVSSAFAGLYVGIGILL
                     IFTIGGLLTDAGSPMTKIVMGLSFAIALSLVIMTGTELFTGNNMVMSAGMLNKGVSIK
                     DTSKIWAYSWVGNLIGALVLGIIFVGTGLVDKGPVAEFFANTAASKASMPFTALFFRG
                     ILCNILVCVSVLCSFRTNSDTAKIIMIFLCLFAFITSGFEHSVANMTIYSVSLFSPTI
                     STVTIGGAIYNLVAVTLGNIVGGALFMGLGTYILGKEKLN"
     gene            51348..53366
                     /locus_tag="JAM15_06205"
     CDS             51348..53366
                     /locus_tag="JAM15_06205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAT6797850.1"
                     /translation="MTKKLVISKTKLFIFIIAFISIFIYLFGSKNTLIGVGIVTAMLT
                     LLERDLTISPIKNLLKYLAINIILGILSFFAVQNMYLGVLLNFIALFIIGYVFSYDLK
                     RAVYVPFGLMYIFMVSIPVGKSEFPMRLSALAVGAVIIMIAQFVMNRNRMKNVGDKEL
                     ISICDELLEKISLLKNTINDDSSIIKSSMRKIDSCNYRINSISKNLKMVIFDNRKDDF
                     YISIRGIDIMNILFSLERISLILERYKKDSKEFEDEDIKNILEESSINSKSDVLVVAT
                     KEINYIKMCLENKDTITDKEILGFRDYVIAQDTKNINLKEIYSVLENLYEFLVDYKKV
                     KSRDEKKAERKSKIPHEFKRLSIYKKNFNLNSIRFSYAVKIALATAVAGFIMDYFHLR
                     DGRWIMLTVFSLTQPYAENCIQRSRKRIEGTFIGAVIFIVLFSIIKDSTLRSLIVLLA
                     GYINSYVVDYRKLMVCVTVSALGSAVVMGDPNVLTISRISYVALGAIIALIVNKFILP
                     YDAKTGYQHVIEMYKGIVKNIIDEVNKSIENVADVYYIKNLLLIPSLIEDRLMLINAI
                     YKDKHQEDFLENQKLLISNMYNLYINVNKNKIKDEDVEKILRDTNYISNYNVDKYDEG
                     RSVILESIVNTKSLGDKIICLNLLQTLNGVKEMYRISNITKVSIKEAA"
     gene            53581..54438
                     /locus_tag="JAM15_06210"
     CDS             53581..54438
                     /locus_tag="JAM15_06210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAT6797851.1"
                     /translation="MSKDVKVKRNKKYDTFSITMELERPLLYDEVENKDDKNNNRKFN
                     IKNKIFKGIGILFVLILLGFFIWINKTYEPQKLAKEALVSNSKVEVTVNENISFTPKG
                     RKVSKGLILYPGAKVEIESYAPLARKIAESGYEVVIVKMPLNLAILGTNKAQKVMDSY
                     NNIEHWVIGGHSLGGVAASNFARDNKLIEGVVFLASYPMGDELKELGKKVISIWGSKD
                     GVVNFKSLVESKQKLPDDTTYVEIEGGNHAQFGDYGKQKGDNDAIISQEKQLNITANS
                     IIKFLKNIS"
BASE COUNT        21626 a         5728 c         9467 g        17625 t
ORIGIN      
        1 aggtaaatct aaatagcaat ctctatgatg atgtagatag agtagaatat ataatcagaa
       61 aaatattaac cttaagtaat gaagaaaaaa atactataaa acttgaagat ttagccgatt
      121 ctatgtatgt aagtgtttca acagtaaaaa atgatttaaa agaagtaaaa agaatgttgg
      181 aaaagtattc aatatcagtt aaatctaagc ataaacaagg tatatgtgtt ttggaaagtg
      241 aagataagat attaaattgt atagttgact taagcaataa gagagataat caattgagtt
      301 taaatgattt tttaaatgat gatataaagg aaagaaaact attaataaaa aaattattat
      361 tagacatatt aaatgaaaat ggattggtat taactgatat tgaatttaag agtgtgttaa
      421 ataatatatt agttatgtta agcagacata agtataatga aaaagaattt atagagaatt
      481 atatagaaaa ttataggagc aaaagaagct caattttaga aaatgaacaa aacaaagaaa
      541 ttataataaa ttcaataaaa acattttgta aaaatttaaa attagctaca tcaatagata
      601 taagtaatga taaggtattt gaagagtttt tatataagca tattagtagt ttatgtaaaa
      661 aaataaagtt aggtataaat caatcaccta taatggctca agatataaaa ataaaatatc
      721 catttgcttt tgaactagct aatatagcta aaaagacaat agaaaaagat ttgaagatag
      781 aaattaatga agatgaagtt gcaaacatag ctctacatat aggaggagca gttgaaagag
      841 catcttataa taataaagat aaggttttca aaactataat agtttgtact tcaggcatag
      901 gcacatcaat gttaataaaa gctaaattag agaatatatt taaggaaaaa ttagaaatac
      961 taaagattat tccttcatac ttagttgaat atataaaagt tatagatgtt gattttgtaa
     1021 tatctactgt tcctattgaa gtaggagatg tgccagtaat aaatatatct ccaattttaa
     1081 gtgagaaaga aattagatta attgaaaaat atatagaaac aggaaatata tacctagatt
     1141 tagatataaa aagcctgttt gatagtgaat tattttttac tgatttggtg tttaaaagga
     1201 aagaagaagt tatagatttt atggcaagta aacttgtaca aaagggctat atagatgagg
     1261 atatgaaaaa atcttacttt gagagagaaa aaatagcaac aacagaaata gggaatatgg
     1321 taactatacc acatggagct attggaaaaa tttttgataa taaaatagca attggtatat
     1381 taaagaagcc tatttcttgg gaaatatcag atgttcgttt aataataatg ttagcccttg
     1441 ataaagataa aatattagat tatgaagtaa tattttcaaa aatatataaa agagtagatt
     1501 ctatagcaaa agttataagt atatgtgaaa atagtagttt tgaaaaattt gtaaatttat
     1561 ttaattagat gggtagtatt gtatatacac ctgtaaattt ggataatata aaactaaata
     1621 aggtaaaaac gataaatttc tcttttaatt aagagaaatt ttttgacttt caaggatatt
     1681 aatataaagt taagatataa acataaagca aataaataaa aaagaggtgg caatatgatt
     1741 tatacagtga cattaaatcc atcaatagat tatatagtta agctagatga gctaaagaca
     1801 ggaagtacaa atcgtgtaaa agaagaatac gtttatccag gaggaaaagg tataaatgta
     1861 tctcgcatac ttaaggaact tggaaatgat aatacatctt taggttttat aagtggtttt
     1921 actggagaat atataataag aacattggaa gaaaaagaat tgaagacaga ttttataaag
     1981 ataaaaagtg gtttttcaag aataaatgta aaaataaagg cgttaaagga aactgagatt
     2041 aatggacaag gtccaaatat agatgatgaa gacattgata ctttatataa aaaacttgat
     2101 aagctaaatc aagatgatat tttaatattg gcaggaagta taccatctac tttagatgaa
     2161 aagctatacg aaaatataat ggctagatta gaaaaaaaga atataaaagt tgtagtagat
     2221 gcaactaaaa atcttcttct taatgtttta aaatataaac cttttctaat taagcctaat
     2281 aacgacgaat tagaagaact atttggtgtt aaattaaatt caattgaaga catgataaaa
     2341 tatgctaaaa gattaaagga aatgggagcc ataaatgtct tggtatcaat gggcaaagat
     2401 ggagcattgt tgattacaga ggaagatgaa gtgcttataa gtgatgtccc taaaggaaaa
     2461 gtaaaaaatt ctgtaggagc aggtgattca atggtagcag gatttatatc tgggtatttg
     2521 aatactggga aatatgatta tgctcttaaa ttgggagcag cttcaggtag tgcaactgct
     2581 ttttcatatg acttagccaa aagagaatac attgataaat tggtaaatga aatatctgta
     2641 aagcagtttt aaaatattaa aaaatatata gaaaggtaat taatatttat gaaaattata
     2701 gatttattag atgaaaagtc aattaagtta aatttaaatt caaaaaccaa atcagaagca
     2761 atagaagaat tagtagattt ggtcgcaaat agtggaaatt taaatgataa agaaaactac
     2821 aaaaaagcaa ttttggctcg tgaagaaatg agtacaacag gaattggaga aggtgtagct
     2881 atacctcatg ctaaaaattc ttcagttact aaagcttgta tagcagcagc agtgtcaaaa
     2941 gaaggtatag attatgaatc gtttgacgga agtttatcaa atctattttt tatgatagct
     3001 gcaccagacg gagctaacaa tactcatctt gaagtattat caagattatc tacaatactt
     3061 atggatgaag actttagaaa taaacttata aattcaagct ctgaaaaaga atttaaggaa
     3121 ataatagata aaaaggaaag agaaaaattc agtgaagaat atcaagatga gaaagtggct
     3181 gaaaaaaata taatagatac taaagagaat gatgctaata agtatcctaa ggttttagca
     3241 gtaacagcat gtccaactgg aatagcacat acatttatgg cagctgaaag tttaaataaa
     3301 atggcagaaa acaaaggtgt atcaataaaa gtagaaacta atggttcagc aggtgttaaa
     3361 aataagctta caaaagatga aatagaaaat gcaacatgta taatagtggc agcagataaa
     3421 aatgttgaga tggctagatt taatggcaaa aaagtcataa aaactaaggt ggctgatggt
     3481 atacacaaag cggaagaact tatagacaag gctgtaaatg gagatgctcc aatttaccat
     3541 ggaggagatg gaagtcacaa cgaatcaaat gaagaaagtg aaagtggatt tagaaaagta
     3601 tacaaacact taatgaatgg tgtatctaat atgttaccat ttgttattgg tggagggata
     3661 cttatagcga tagccttttt acttgatgat tatactatta acccttcaaa ctttggttca
     3721 aatacaccga tagcagcatt tttaaaagga ataggagata aagcttttgg atttatgtta
     3781 cctgtacttg ctggatatat agcatactct atatctgata gaccagcgtt tgttgtagga
     3841 tttgtaggag gtgctctagc aggtgatggt ggttcaggat ttttaggtgc actacttgca
     3901 ggttttatag caggttattt agtagaaggg cttaagaaaa tatttagtgc actaccagct
     3961 tcattggaag gaataaaacc agtattgtta taccctttac ttggaacact tttgatggga
     4021 attataatga catttttagt aatacctcca gttacagcaa ttaataatgc aatggttgga
     4081 tttttaaatg gtttaggtgg aacttcaaaa atagttttag gattagtatt aggtggaatg
     4141 atggctgtgg atatgggtgg acctgtaaat aaagcagcat atgtatttgg agttgcatca
     4201 cttgaatcag ggcagtttga aataatggca gcagtaatgg ctggtggtat ggttccgcca
     4261 cttgctatag ctcttgcaac tacatttttt aagaatagat ttactaaaga agaaagagat
     4321 tctggtaaag ttaattatgt aatgggatta tcatttgtta ctgaaggagc tatacctttt
     4381 gcagctggag acccacttca tgttatacca gcttgtgttg gaggttcagc agtggcagga
     4441 gcacttagta tgttgttcaa tgtagctctt cgtgcacctc atggaggagt atttgttata
     4501 ccagtggtta ctcatccatt tgcatatata ttagctatag ctgtaggtgc tttggttgga
     4561 atgatgcttt tagcattact taaaaaacca ttaaatcaag aagtatagca attaaaggat
     4621 attcaagaac ttaaaatatg atgttttata aaaattaata tattgctgaa ttattttaaa
     4681 ataaggattt tatgaggctg ttatataacg atttgtaatt gttatcttga cagtctttta
     4741 tttttatata agtaaaataa gtgtgttttg ctttatttgt atttaaattg tttttaagtt
     4801 agaatataaa gaaaattata tattatttta atattcactc gaactagaaa ataatatttg
     4861 ttgtattttt tgtatataaa atatattgta atattaaaaa aataatagta aactgattgc
     4921 ataaaaatga tttttatata aaatttaagc agaagaataa atttctaacg aaattggata
     4981 tttcttctgt aaatacatat tcaaaaaaag aattataaga gtttagtcag cagtcgtgta
     5041 agtaataagg actttataaa tatatagaaa tataatgata ttaatataac caagcgattt
     5101 ttaatttagc tttttaataa gcttattttt tatactattt ataataaata aactccatga
     5161 tgggaaaact attactattt aatatgtaaa ggagtatttt aaatgaatga atcatattgg
     5221 tttttaaact caagtccaaa agaatataac aaattaggtg aaaatataaa aacagattgt
     5281 cttatagtag gtggtggaat aactggattg acaactgcat atttattagc aaaagaaggt
     5341 aaaaaagtag tgcttgttga ggctgataaa ataggatatg gaacttctgg aaggaatact
     5401 ggtaaggtaa cttgtcagca tgatatattt tactctaaga tagagaaaaa atatggatta
     5461 gataaagcaa aatcatatta taatgcaaat aatgaagctt taaatttagt tgaacaaata
     5521 atagaagaaa acaatataaa atgtgatttt aaaagggaaa cttcttttgt atttacagaa
     5581 aaagaggata ctataaagaa tattaaagat gaatatcgta catgtaaaaa aataggaata
     5641 aattgtgagt atcatgaaac tatagaaaat attccattag atataaaggg ggctattagt
     5701 tttactaatc aaggtcaatt taacccaaag aagtatattg atggattggc aaaagcagca
     5761 gtaaatttag ggctaaaaat atatgaaaat acaccagtag tagaccttga aaaaggaaaa
     5821 atatgtaggg ttaaaacaag agaggataat ataatagaag ctgagaatgt tataatttca
     5881 tctcatagtc catggtatga tggattgaat ttttattttg caaaagaata tgcagagcgt
     5941 gcttatttaa tggttgcagt tttggaaaat aaattagcag atggtatgtt tataagtata
     6001 gatgacccat caataacttt tagacaatat aatgatggaa gtgaaaattt actgattttt
     6061 ggaggaggag accataaagt tggtcaggga ggaactgaga aagaaatatt tgatgattta
     6121 gagcattatg gtaaagaagt ctttaaggta aaagatttta aggggaaatg gtctgctcaa
     6181 gacaatatga gttttgacaa tgttccttat attggttata tcaacaaaag agaagacaat
     6241 atttatgtag ctacagggtt ctctaaatgg ggaattacta atggaactgc tgctggaata
     6301 ataataaaag atttgataat aaataataat tctgattata aagatacttt taatccatcc
     6361 agattaggta gctacttttc aaaagatttt ataaaggaaa atgcaaacgt agcaataaat
     6421 tatgtaagtg gaaaattaaa aataggtagt ggagatatgc ctaaaaataa tggagaagga
     6481 aagattgtta atattgatgg aaaaagatat ggtgtatata aggatgataa tggagatttt
     6541 tatattgtag acacgacatg tactcattta ggatgtgaac ttaattttaa cagtgaagaa
     6601 aaaacatggg actgtccatg tcatggttct agatttgact ataagggaaa tatacttgaa
     6661 ggaccagctc ttaagccatt aaaactttat ggacatggtg ataatgatgt taatcctaag
     6721 ttattataaa attattttta ggaaggtaaa gtgtatatga ataaactttt aaagccaata
     6781 actatactat tgtatatagt ttatatttta tctgccgtat tttttgtagc aaacaaagaa
     6841 tatggaagtc taggtctagt agcaattagt ttagttggta ctttcatttt gagttttata
     6901 aataagcaaa ctgaaagatt attgagtaaa gaattatata taatgcttgc tttatttata
     6961 atgttttcat cattgttagg tacttgtttt aatttttatg atataaatta ttatgatgat
     7021 tttttgcatt tatggtcagg tataatatct tgtattgtgg ctttttctat aattaaatac
     7081 ttttatacac aaagagagat aagtaaaatg agtaaagtgt ttttagttat atttttattt
     7141 atgtttagta tgggagtagc gagtttatgg gaaataggtg aatttttaat ggatactttt
     7201 gttgggacta ctacacaggc cggagggtta gaagatacta tgattgatat ggtagatgct
     7261 ttaataggca caattataac tattcctttt atagtaaaaa aatctaatat atagttttaa
     7321 attttttata ttaattataa tggatttaat taatcatgtt gagtttcaag gtctatatga
     7381 ttaattaaat ccatttttgt tatttataat tattattgaa tatattttta catataagat
     7441 ataaggtgat agatagaaat tgttggatta tgtaaataat taatatataa taccattatg
     7501 ggcaataaat acaaatcaaa tgataatata gtctatttat gtaaatgtta tattgtatcc
     7561 taagtataat agtaagtttt ttgatagtgg tgtagaaagt aaaaatctac tagcctaaat
     7621 tgatgtatgg attagtttag gaacagtaat tgcatatctt aagtttgatg tcatgttggg
     7681 ctactagaaa taggtcatct ttttcacttg aatatctttt ctttaaacat ggggagtatc
     7741 atatcaaaaa catatgaaaa ttaagtgatt tatgagaaca gtaatatttt atatgatagt
     7801 atagaatagt aataaagtat taggaggaac attgagtgtt aaaaaagtgg tttggtattg
     7861 tgaaaaaaag acaaaaaagt gagtcagtaa aagaagaagg tgaagtaata ttaaaaaacg
     7921 aaaaaatatt atctgaagaa aagttgatag atgaagaagg agttgtagtt aatattgata
     7981 atgaaatatt aactaaagta gaagtagtaa atgatgacaa tgaaatagaa gaaaaaataa
     8041 tagaagaaga ttggttaatt agtgaaaata ccataaaatt agatgataaa gaagcaatta
     8101 ttaatgataa aaacatagaa ttatgtaaaa aagaagttca agttgaaagt gaaaaaatag
     8161 gtttaaataa gtttgaagga ctggaccaaa atgaaaatta taatctagaa aaaaatgtta
     8221 ttgaagaaaa aaaagtaagt gaatgtttga cagaagaaga tttagagtac ataaaagaaa
     8281 ttaaaataaa aagaggaaaa agtataaaag ctataaactt gtatactaaa gaagagtggg
     8341 tttttgacac tcatatacag tgtagtaaaa aactcaaagt tccattaggg tacataagag
     8401 aaaatttaaa atatggatat atggattact ttggagatgc aataaattat ttaagtgaag
     8461 tattaaatat agatgaatac tgcaaaagtg aatggagcta tctcgataat agcaaatctc
     8521 catctgagat atttaatatt ctaaacaata aaatatttag tataaggctt tctaatgaaa
     8581 aaagaaatga aattttgaca aatgataaaa ttgaagcatt aaaaatgaat tatagatttg
     8641 aatgtattga tgaagaatat gatgaatatt ttaaaaaata taagtctata atcaaaagag
     8701 gtggaaagaa aaaagttgaa ttagtaaata aaaaaggtga cattttagaa atatttaagt
     8761 ctttagaaga atgtgccatt tatttgcaaa aggaaaagaa tgaagttata caaatgttaa
     8821 aatatggaga tacaaaagta ggaagaaact ttataaggta tagtttgaga agtatttaat
     8881 ttcattttaa attcataaga gtttcatttc tgattcacac atttaatatt attttaatgt
     8941 aaaataataa aggtgaagta ttgcacaatt aaaattaagg agggtattaa tgtctgaaga
     9001 aaaaaatcca aaagaaaata cattagatga acctaaaaat tcagataatg taaattctaa
     9061 aaaagatgat gtgtcagatg aaaaaaatac tgataacaaa gttaaaaaaa gggaaataaa
     9121 gctaaacaac aaaacactta aagctattgt agcaattgtt gcagtaggag ctatatgttt
     9181 aggtggaggc tatgtttttg gcaaagaagc tggaagaaaa ttgcctgcta cttcaaaaca
     9241 ctataatagc agtgaggtag tagctactat tggggataaa aaaataacag gtgaaatgtt
     9301 aagaaagaga atggagccat tattttattt aaatgcaaaa actactatga ctgatgacga
     9361 aatacgttca tatgaatcaa atatgattga aactatgatt acatctgata tattatcctc
     9421 tgaagcagca aaagagaaaa taagtataac taatgaccaa ctagatgctc agtataataa
     9481 tttaatgagt agtatagaat cagcaatggg aatgactaaa gaagagtttt taaaacagtt
     9541 tgatttgact gaaaaatata taaaagatga tatgaaaaaa gagctagtag catcaaaata
     9601 tttaaatgaa aaatcaaaag ttactgataa agaagcagag aactattaca ataaaaacaa
     9661 gagcaattat ttacaagtta gagcttcaca tattttaata aaaactgttg atgataaagg
     9721 taagcaagtt agtagtagca aaaaagctga acttaagaaa gaagctgaag aaatacttaa
     9781 aaaagcccaa gctggggaag attttgctac tctagctaaa aaatactctg aagatagtag
     9841 tgcagaatca ggtggagatt taggtttctt tggtaaaggt cagatggtgg aatcttttga
     9901 aaaagcagcc tttgcattga agaagggaga ggtatctaac aaacttgtag aaagtgatta
     9961 tggatatcat ataattaaga aaactgatga aaaatatcag ccatttgaag aggtaaaatc
    10021 agatttagta agcagtttaa catcagaaaa acaaaaccta cttatacaaa atctaaaaga
    10081 aaaatataat gttaaaatta cagataaata tcaaatgaaa gctaaagaat agataaagtc
    10141 aatttattaa aaaaaagaaa aattaactgt atggataaaa gctattttta ctctcaatat
    10201 agagagtata aaatagcttt tattattttg caataaaatc tatttatata tatgaagtga
    10261 caaagaaata acatgcaaaa agatattaaa aagaaatatt tttaatttga attttttcaa
    10321 taaaaattta caaaaatgaa aaaataaaca aaaaagaatt gaagatttaa gttgttattt
    10381 aaatatatat atattaagat tttctgctga agatactaaa aaaataatat ttttcataat
    10441 tttaaaaata ataataaaaa aatgaaaata caggcgataa tctattgagt aaacatagaa
    10501 aagatgatat tataagtatg tgctaaaatg gttaaagcaa tattaatatt aaatttaact
    10561 ataaaacaaa agggggcgtt tttttatgtc aagtacagaa agcgtatcta aaaaaagtgg
    10621 tcatccgaag agtttttggc ttatttgcat gacaattttg tgggaaagat ttagttatta
    10681 tggtttaaca gctttattgg tattattttt tacagcaagt gtagctcaag gtggtttagg
    10741 tctttctact caagaagcaa catccatgtt tggcttattt acaggtctta tatatcttac
    10801 accattagtc ggtggctggt tagcagataa agttttaggt caacaaaaat gtatttctat
    10861 aggtgcactt ttaatagcaa taggagattt cgtactattt gcttcatcta catctattgc
    10921 catggtttgg gtaggtctat caataattat tttaggaaat ggttttttta aatcaagttg
    10981 ctcaaatata gttggggata tatatcctaa aactgatgtg tcaagaaaag atgcagcata
    11041 cagtttattc tatatggcag taaatgtagg agcatttata gctccaataa tatgtggatt
    11101 gctttctgat aatgtatttg cagtaagagg agcaagtgga gatatagtat cttatggata
    11161 taagatggca tttttaattt gtggtatagg catgatgtta ggtatgatta tatttacact
    11221 tcttgcacca aaattattaa atgaagtcgg aaaatatcct gtgactaaag gtaataaagg
    11281 tgaaaaaatt gagtatggac cacttactaa gttggagaaa aataggataa tagcaatggt
    11341 tattttattt ttatttgtgg tcttattctg gacagcatac tatcaaacac aaagttcttt
    11401 tatgatttat gtaagggata atgtaaatag aactctattt ggatttgaaa tgccagtagc
    11461 atggcttaca tcactaaatg ctatattatg tgtggcttta tgcccagtat tagctaccct
    11521 atgggttaaa ttatctcata ccaaaagagg tgatttctct attccagtta aaatgggatt
    11581 aggaatgata ataatgggtg ttgggtttat agttatggta tttgctacat tagctaatgg
    11641 tccagatgga atggtaaagg ctagtatatt gtttatagta ttgacttata tatttacaac
    11701 agtaggtgaa ttattcttat ctcctatagg acttgcaatg ttcaataaat tagctccagc
    11761 taagtatgct acgttgtcta tgggagcctg gtatctaaca agtttttttg caagtttatt
    11821 atcaggaaag attgctggtt ttacagccac acttggtttt ttacagatat ttggaggaat
    11881 agcaacagtt ttaataatat ttggtttaat attattggga ataagaaatg tattaacaag
    11941 attaatggct atggatttac taacaaaaga aaaataattc atgacgaatt attgtaaata
    12001 aatgaattac tttaaataaa ggaagttaca tttaaatata aaattaaatg taatttcctc
    12061 tttgattatg aaaaaaagct ttacacaaat agatattata attaaaatta taattgtgat
    12121 aattagagtg tataagattt atataaatta tacaaaaaat atttatgtaa taaactttac
    12181 atacttatat atttagttat tcaaactatt atttcgagga ggtcttgttg tgaatataaa
    12241 agatagatta agtggattaa gaaaatttat ggaagaaaaa aatatagatg cctatatgat
    12301 tccatcttct gataatcacc aaagtgaata tgtaggagat tacttcaaat caagagaatt
    12361 tatatcaggg tttaatggtt cagcagggac ggttattgtg actaaagacg aagctgggtt
    12421 atggacagat ggaagatatt ttatacaggc agaatctcaa ttagaaggaa gtacaataaa
    12481 attattcaaa atgggacaag aaggttgccc aactacagat gaatatttat ataaaaatat
    12541 tcctgaagga ggaactttag gatttgatgg tagagttata tctgctagag aaggagctac
    12601 attagctgaa aaattatcta aaaaaggtat aaagatagaa tatcagtatg atttaataga
    12661 tggtatatgg ccagatagac ctgctttatc agatagtaaa gcatttttat tagatgttaa
    12721 atattgtgga gaaagtttta gctcaaaatt agctagatta agagaaaaaa tgagtgaaaa
    12781 aggtacttct actcatgtaa taactactct tgatgatata gcatggttat tcaatataag
    12841 aggtggagat gttaaatata atccagttgt actttcttat gcagtaataa ctttaaaaga
    12901 agtttatcta tttgttgatg aaagtaagtt aaatgaagaa atattagatg aactagctaa
    12961 ggaaaatgtt caaataaagc catataatga tgtgtatgaa tttgtaaaaa atatagacaa
    13021 aactgaaaaa gttttattag atggaactaa gcttagttat acaatttaca ataatatacc
    13081 ttgtgaagtt gagaaagttg atgagttcaa tccagtaatg ttttttaaag ctcaaaaaaa
    13141 tgaggtagaa ttagaaaata taagaaattc acatgtaaaa gatggtgtgg ctttcactaa
    13201 atttatgtac tggttaaaga aaaatgtagg taagatggaa atcactgaaa taagtgctac
    13261 tcaaaaatta gaggacttaa gaagagagca agaaggtttc tttgagccaa gtttcaatac
    13321 aattgctgca tataaagagc atgctgcaat gatgcactat agtgcaactc cagagtcaaa
    13381 ttataaatta gaggcagaag gattattttt agtagattca ggtggacaat attatgatgg
    13441 aactactgat ataactagga ctacagtttt aggacctata agtgatgaat taaaactaca
    13501 ctttacttct gtagcaagag gaatgataaa tctttctaag gctaagttct tgcatggttg
    13561 tagaggatat aacttagaca tactatctag aagttgcatg tggaatatgg gaattgatta
    13621 tcaatgtgga actggacatg gtataggatt tgtgctaaat gttcacgaag ctccaaatgg
    13681 atttagatgg agagtagtac ctgaaagatt tgatagtgca gttcttgaag aaggaatggt
    13741 aactactaat gaaccaggta tatatataga aggttctcat ggtataagaa cagagaatga
    13801 aattgtagtt agaaaagctg aaaagaattt ctatggtcaa tttatggaat ttgaagttgt
    13861 tacgttagct cctattgact tagatggtat agtaccagaa ttaatgaata aggatgaaaa
    13921 agattattta aactggtatc ataagttagt ttatgataaa atatcacctt tcttaactga
    13981 tgaagaaaga gaatggttaa aagtttacac tagagctata tagtttgtac tagatacaat
    14041 aaaaatcgag gtattataat gcctcgattt tttattgtat attttattaa ctttaaaaaa
    14101 tttttaattt gataattcta ctaatttttt attcattata agtagtataa ttccaaatat
    14161 caataaaaat gatggtatca ctatgaagac ttgtaacata ccaagttggt ctataatagc
    14221 ttgcgtatag ccagataatt tatttgctgc aaatttgcct aaaaaccaaa cacccattag
    14281 gaatgaaata tacttttcag gcgaaagttt atttaccata ccatacccga ctggagaaaa
    14341 gcaaatttct cctatacttt ggaatgttaa aaatccaact acccaaaata cacttgcttt
    14401 gtgaattgaa ttagggtctg ttcctgtttg tataactgct actatcataa acaaaaatgc
    14461 tatagctaat agtataaaac ctaagctcat tttttttggc acacttaaat cgcctttttt
    14521 agtttgagat aattttaccc atactaaagc agagataggt ccaagaataa cacaaaggag
    14581 accattgtat gaatctatcc atgaagtagg aatttgaaaa ttgccaacag taagatttat
    14641 gtgttccttt gtatagagtg caatagacat agaggcttgg ttatatgcta tccaaaaaaa
    14701 tactgtgaaa aaagctaaca ccaatattac tattattctt tttttctcaa tcaaagttaa
    14761 aggtcttgaa gcgagcattt tcttatattc tagtgatttt cttatagact ctctcccgtt
    14821 actagggtca ttattcaaag gtttataaaa ctttctgttt ccaaatataa agaagaataa
    14881 acctattaga accgtaattg atgaaaataa aaatacatat ctatatccat acatacttat
    14941 agataatccg cttttcatag caaaccattc attagcaact aaaccgcata ttaaagggcc
    15001 aaataaagta cctagattag tagccatata cgtaatagag aaagctccat cttttcttgg
    15061 gtcatcattg gtatataagt ttccaaccat agtatgtaag tttcctttat aaaaacctat
    15121 tcctaatcca gataaaaata tcatgatgtt tatatccatc ttactatttg ctatgtatcc
    15181 tagaaaataa ccaattgaaa ccattagcat tccaagtata atacagtttt tgggacctaa
    15241 aaatctatca ctgacccatc caccaataac tggagagaaa taagtccatg ctaaaaaaga
    15301 tgcaagcatt gatgcggatt ctgctggtgt taaccctaaa ccacctttgg agacttgttc
    15361 agctaaaaac aataataata ccaatttcat accatagtat gcaagtccta caaaggtaaa
    15421 tattgaacag cagaaatata aatctctagg ttgtttaagt ttttcttgcg tttttaaaac
    15481 tgacatatgt cgagaacctc cagataaata gtttaacaaa attttaccat actatatgag
    15541 tatatgtttt tttcatatag acgtcaactt gtaagataat ttaattaagt cgaaatatat
    15601 gtaaaaatag tatcattttt gtgtattcag taatattttt ttatgataat atatgttatt
    15661 attatattaa aatacaaaca tatttatgga aaggatatgc caatttagta gttagattga
    15721 ttgtttggca ggtgggatga gctatgataa gaaagaaatc tgaattacaa gtagaagtaa
    15781 aagaaaattt aaatggtggt ataggaaagg ttaagcttga aaacataata caaaatgaag
    15841 agcttaaagg aaaaggaaga ctatttaaaa gagtagcttt accagtagga agttcaattg
    15901 gtgtgcatga ccatacaaca gattttgaag tatattatat actaaaggga aaaggtaaag
    15961 tatttgataa tggggaattt gtagaagtaa atgagggtga tgtagtgtat acagctgatg
    16021 gcgaaaaaca ttctatagaa aatataggag aagaagatct tgagtttgta gcactagttt
    16081 tatatatgta aaatatggag gaggagtcat gacaggcaag atagaagaaa ttaaggacaa
    16141 gataaataga ttttgcaact ccaatttaaa tcaagaatac aaagatataa gctttaaaat
    16201 tttgcaaaac cttttagata ataataaaga gataattcat tcttctagag ctgatatatg
    16261 gtcttcagct atactaaata tagttttaga acaaaatctt ttatacaata agaagcatcc
    16321 actacatata acaaaaaaag agttttcaaa acaaataggt gtttctttaa atactataaa
    16381 taataaatcg tctttaataa aagatgtttg tagtattgac tttttaaatc aagatactat
    16441 agctatttct aatgtagaat tttgggtaaa agagaccaat tccaaatcaa agtctgtaga
    16501 tttagattta gaaaagaaga aaatactata taaaagatat attaagctat cacaagatgc
    16561 gaatagtgat attgaatcaa ttagatatat ggaggaagct gtaaatatag gtaaaagtat
    16621 gattactaaa gaagataaag aacttggatt ttggaaaggt ttatctacca gagcctatat
    16681 gatagcactt gaatcccttg ctagaaagtt agaaagtatt aataatctaa aggagtccaa
    16741 aaaagtatta gaatatttaa tagaaattaa tcctagtgat gagcagggaa taagatacaa
    16801 attattaaat gtattaatta gattaaatga tagaacttca ataaataaat tatttgaact
    16861 ttataaagaa gaaaaatctg ctacatggat gtacagtaaa gctctttatt actttaaaaa
    16921 taaaagtatg tttttggcaa atgattctat taaggttgct agaagtaaaa ataagtatgt
    16981 tggattatat ttgttagatt ggcgaaatgc ttttggtaga gaatttgtta cagaggaaga
    17041 aaaggcagaa gctgtctatt actatgatga aaacatagtg atttggaatg aagttaaagg
    17101 ttctatggat tggctattaa aaaaaatgtt ggaattttca taaaaaaaac tactccttac
    17161 ttttatataa gtaaaaggag tagtttttaa tttatacatc tagttttaaa tcttcaggtt
    17221 ttattagacc tttttttctc ataaattctg aaatcaacaa agttacaata gcaggaagta
    17281 taaaattaag taaaagtata ccaacccaca tagatatacc tccttttcca gcactttgca
    17341 tagcagttac tgttccaaat tgtccaacca atccacaagt acccatacca gaaccaatag
    17401 gaatattctc cattttgaat attgttgtag ataatggtcc aagtaatatt gaagctacag
    17461 taggtggtat ccaaattttc caatttttta ttatattagg tacttgcaac atagatgtcc
    17521 caagaccttg tgccacaagg ccaccaactc cattttctct aaagctcata acagcaaagc
    17581 ctaccatttg gcaacaacaa cctacagttg ctgcaccacc agcaagacca cctaaactta
    17641 acatcataca aatagctgca ctacttatag gtaatgtaag agctattcca acaagtgcag
    17701 agactaaagc tcccattatt ataggttgca tagttgtagc ttgcattatt atatttccaa
    17761 atgaagtcat aaaagcagaa acagctggac caataagttc agctacaagt actccaatta
    17821 gtattgtcac agcaggtgta accaatatat ctatttttgt ttcttttgaa actaattttc
    17881 caacctctac agcaaaaagt gtagcgacaa atgctccaac aggtcctcct aattcattac
    17941 cacaagctcc aacaagtgca caagaaaata gtacaagtgg aggtgcttga agtccatacg
    18001 caatagccac tgctatagct ggaccagtaa cctgtttagc aagagggctt ataacttcag
    18061 taaaaagaga aatattgaaa ttatctccta atgtattgaa aattgttcca attaaaaggg
    18121 acgaaaaaag accgagtgcc atataactta gtgcgtcaat aagatacctt tgaacagaaa
    18181 tttcaatatt ttttctttta gcaaatgatt tgaaatttct ttttttataa ttgatttcca
    18241 atttaaaatc ctcctcatat aatataagta taatttcttt ttaattaatt atataacttt
    18301 tcagctgaca agacaaatgt tatttcacta aaattagact attgtaatag taagaaatta
    18361 acattaattt tagttttaaa ttttaaattt atggtttata attagtatag ggatattctg
    18421 aaatataata attttccagt ttatcccaat atttaactta ggtagattgc ttacaaaaca
    18481 aatgattata tattaggcta aaaggaagtg gatagatgat atttgtaaaa aataagaaat
    18541 acagaaaaat tgccataatt atatctattc ctatattgct tgttgcgcag tactaccttt
    18601 ttaaatttgg aatacttaga ccaatggtaa agggagtaga aattgaaatt gtagatgggg
    18661 aatatgttaa agatatagat aaatatgtag taaaattaaa tgaaacagtt actttgtcta
    18721 caggtgaata tattaaggtt ccttcgtatg ctaaaaatcc aaatatttgg tttaatgtat
    18781 tggataactc agggacttta aaaatagatg gaaataaaat gacagcatta aaggttgggt
    18841 attcttctgt gggtatcatg aaaaattcaa gagtattaaa aaaggctact ataaaagtag
    18901 tagacccaga ggtagaatca ctagatatgg agattaatgg ggatttaaaa catgttggtg
    18961 atagtgctac tatagaaagt acaatagaag ttgattatga taagtttaaa aaatcatata
    19021 agccagttta taagagtagc aatgaaaata ttttaaaaat caaaggaaat aaagtaagtg
    19081 cagttggagt tggtaaagct acaatatatg ctaagtgtgg aaataaagaa attgagagaa
    19141 catttaggat tcaagctaga gttgctgaaa taaatatgga tgatataaaa atagaagttg
    19201 accaaaatga aaaattgaaa ccagatataa taacttctcc acctggttta gaaccaccaa
    19261 aaatatatta tgagttagta gattcaaaat tacctgtaga aagagcaata agtttaagta
    19321 gtaatggaaa tgttgtaggt cttagagaag gtaaagatag ggtgagaata acttgtggag
    19381 ataaatctaa agtaataaca gtaacagtag tcaaagaaac tataacgaat gactatatac
    19441 aaaacttggt tggttcacat aaaatagtaa acaataaagt tattattaaa cttgaatggg
    19501 attatatgaa agatgtcttt gattatgata tatatcttaa agataagttg tcaggagaat
    19561 catttaagaa aattaaatct ataactataa atgaaagtga tttaggtaag tctaacaagg
    19621 tatatgcaac tatagaagta gatatgaagg gtaatcaaaa tatagatttt gatatttatg
    19681 tcatagggaa aaaggattca gatacaacta agccaagtaa tgtaataaat attactaatg
    19741 gaaatggaaa ttcaaataat gataataata ttaaagatat gagggtagaa aatatatcag
    19801 ctaatgttga tagagataat aatgtcatta gagttaactg gagtagtata tctcataagg
    19861 actgtactta cagtatatat gtaaaaaata atactaatgg agatggagaa tttactctat
    19921 atcaaagtga tatacaggga aatgagcata ctataagtat tcctgaagga gatttaaatc
    19981 tagatattta tgttgttgca aattataatg gaaatagctc tcaaaatagt gatgttataa
    20041 atgtaagata gatttgtata caaattgaaa gtgttgagtt tatttaaata ttaaattaag
    20101 aaaaaggata gtatagggta attatactat cctttttttg ttacaatata taggtttaaa
    20161 atctctagta atataaatta taaaaagtct tatttacaca aatctataga tatttttttt
    20221 attaatcaat attgtcttaa attgaactta gtgcggcttc tattgcatgt attactgttg
    20281 tatcaaatag aggaatagaa gtgtcatttt gtttaattaa aagacctatt tctgtacatc
    20341 ctaatataac agcctctgca ccttgtttgc caagcttatc tataatagat aagaaagctt
    20401 tttttgaaga ttcagatata attcctaagc aaagttcgtt aaatattgtg tcatttacta
    20461 ttatacggtc ttcttcattt ggaattaaga cttcaattcc attattaata attacatttt
    20521 tataaaaatc ttgttccatt gtatatttag tacctaataa ggccactttt tttatttctt
    20581 tttcccttaa tactgtagca gttacatctg ctatgtgaag taatggaata tgtatacttt
    20641 cttgtatttt atctgatacc ttatgcatag tattagtaca gataacaata aaatctgccc
    20701 ctgcctcttg taatttaatt gcagcatcag ctaaaatttt ggcgcttttt tcccaatttc
    20761 cactagattg gcattcttca atttcttgaa aatctacact gtaaagtata catttagaag
    20821 agtgtagtcc acctaatctt tcttttatta ctgtattaat aacttgataa tatgtaatgg
    20881 tactttccca actcatacca ccaattaagc ctatagtctt catattatac ctctcttatt
    20941 tatttatttt gaaatagcta tttacaaata caagtatagc atctaaaata gaagcataca
    21001 ataatgaaat tgtatggagt acaattataa ttaagaggag taattatatg ccaataaatt
    21061 cttttgaaaa ctatcctatg acatggaaac caaagttaga taaccgaaaa ccaccaatat
    21121 ataaaacttt agcaatgtta ttagaagaag atattaaaag aggaaattta aatcctggag
    21181 ataaattgcc tccacaacgg gaattagcag attttctaga tttaaactta agtacaataa
    21241 cacgagcatt taaactttgc gaagaaaagg gactaatatg tgcaaaagtg ggaaagggaa
    21301 cattcatttc ttctgatgta aatgtaagta atacattatt atatcaaacg gaatcaaaag
    21361 acataattga gttggggaca gttcatcctc cgtatgagca aaatacatat attattgact
    21421 ttattaaaaa tgtactaaaa caaccagaaa tggataggtt tttacaatat atgtctccat
    21481 ctggcacata tatgcaaaaa aagtcaattg caaaatggat agaaagaaat aatgtataca
    21541 ccagtgaaga aaatatatta ttatctacag gagggcaaaa tgctatatgt gcaactttac
    21601 taggattatt taaagctggt gatagaattg ctacagattc tttaagcttt tctggaatta
    21661 agtcaatagc taaaatgata ggtattcaat tagtcccaat tcctcaagaa aataatgaaa
    21721 tatcgattga atatcttgaa agttattgta aaaatgaaaa tataaaaggc atatatctta
    21781 taccagatta tcataatcca acgacacata ctatgtctga tttatctcgt aaaaagatag
    21841 ccaagatagc aaagcaatat aatataataa ttattgaaga tgctataaat agcattttta
    21901 gagacggtat acaaactccc atattttctt tagctagtga taatactata tatattttta
    21961 gtacatctaa atttttatgt gctggtctta gagtagcatt tgtagttgct ccaaaacgat
    22021 atatagaaaa tttagaaaat gcactatata atatgaatct aatggtttct ccatttacag
    22081 cagaaatagt acaccgttta ttatattctc ctattataga taaaattata gaagagaaaa
    22141 gagatgcaat tatagaaaga aatgaagttg ctgataaagt tttgtcagat tataatttga
    22201 ttggtgataa gaattgcagt tttcgttggt tacttcttcc tgatgaattg gatggaaaat
    22261 catttgaaat ttctgcaaaa aatctaggag ttcaagtata ttgtgctgaa cgattttcag
    22321 taggaaactc tacagttcca aaagcagttc gtatttgtgt aacagctcca aaagatgtag
    22381 aagaattaga aaaagggctt aatataataa agtcacttct taagagttaa atttatttta
    22441 ctattattta attaaataaa taaaaaggcg gagaaattta ttataataaa cctccgcttt
    22501 tattatttaa tgaaatactt tactttttat taaaaaattt aattttaata atcttgaaaa
    22561 tataatcgtt ttatggtaaa ataattctta aaaatagaaa aaattaatca tttgttaaaa
    22621 aaaatgcata atttattgta atttattgac gaaggttgaa aaatattcat aaatgtgcga
    22681 aataacagaa aaaatgcaaa aattaattca atttcatttg ttataaaatc tatatggcaa
    22741 aattaaatct gcctatcaga atgatataaa cacatcagaa aggaggacgc tatcaaataa
    22801 tacaagtagt taactttgat agcaaaaaat tatgaatgaa caaactagaa tatccttaga
    22861 gagagctgct gaattaaaat caaaaattga tgattatatt caggctagaa aaacgattaa
    22921 cagaggtctt gaaaaagaag aagagataaa taaacgaaaa cagaaaatat taagtatctt
    22981 aaatggaact gaagaggatt ggaataacta caaatggcaa ttatcaaata gaataacaga
    23041 tgtagatact ttatcaaaaa ttataactct aactaaaaaa gaaaaagaat atataaaaga
    23101 ggttggtact caatttagat gggcaatatc tccatattat ttgagtctta tagacccaga
    23161 agatatatgt gacccaataa aattactgtc tataccaaca catatagagt tggaagatga
    23221 acaagaagat ttggacccaa tgggagaaga gtatacaaac ccagcaggat gtataactag
    23281 aagataccca gatagattaa taataaatgt aacaaatgag tgtgctatgt attgtagaca
    23341 ctgtcagaga agaagaaata ttggacaaca agattctcat aagtcaaaag ctattatcca
    23401 agaatctata gactatatca gagaaaatga agaaataaga gatgtactag taactggtgg
    23461 agatgctctt acattaaaag atgattattt agagtggatt cttagccaac ttaaagagat
    23521 accacatgtt gattatgtta gattaggtac taggactctt gttacaatgc cacaaagaat
    23581 tacagatgaa ttttgcaata tgctaaaaaa atatcaccct gtatatataa atactcattt
    23641 taatcatcca atggaaataa ctaaggaatc taaagaagct tgtgaaaagt tagcaaatgc
    23701 aggagttcca ttaggaaatc aggcagtatt attaaatgga ataaataatg ataaatttgt
    23761 aatgagatgt ttaaatcaag aattactaaa aataagagta aaaccttatt atatattcca
    23821 aagtaaacat gtaaagggaa caaaacattt caatacatca gtagatgatg gtcttgaaat
    23881 catggagtat ttaagaggat atacatcagg aatggctata ccaacatata tagtaaatgc
    23941 gccaaaagga ggaggaaaga ctcctttgct tccgcaatac cttgtatcaa aaggaacaga
    24001 ttacgttatg cttagaacat gggaaggaaa agttataaaa atggaagatg aacctgctgt
    24061 agatataaag aaacttataa aagagcaagc acaggattaa aaaagtattt aaagtttata
    24121 aaaagaaaca actttaaaat aaaaagaaaa tggatgtcaa atttatatca atttgcatcc
    24181 attttttatt agttatttat tattttgttg ttgattaact aattcaagat atccacttgg
    24241 gtggaagtaa tatatctcag aagtattttc atttacaaag taaccaatat caccatctgc
    24301 atctggtaaa aatacataac cattaagatt tttagctttt aatgcttcaa aatcactagc
    24361 atttccctga tatatgtaat caacttcatt gttgtatttt actaaaagtt ctttagcttg
    24421 ttcttgagtc aatttagtat tttggcttac aggaacattc ttttgagaat ctgcataaga
    24481 agattcattt actggtgcag ttaataacaa acaagataaa actaataaag atataagtgc
    24541 ttttttcata ctaaaaccct ctttcatgtt taattatata agattcatta cttaataata
    24601 ttgtatgttt cctataatta aatattacca ttaaagagaa taatattaca gttacacagc
    24661 tgtaactttt gattacaaaa tcgtaattaa attgtatttt tattccattt gtattttatc
    24721 atgtctacga tttacaaact cacagaagta tatctttata acgcccatca caggagcaga
    24781 tagaatcata ccaggtatac caaagaatcc tccaccaaca gtaactgcta ggattgtaaa
    24841 gaatgggcta agacctagtt gtccacctac gatttttggc tctataaatg taacttcaac
    24901 ttgttgaatt attattaagt aaattaaaga agttaaagca attgttggat tggagaataa
    24961 attaattatt acaactggtg ccatacctat tactggacca aaatatggaa ccatattcat
    25021 gacacccata agtgtaccaa ataatagtgc atattcagat tttaaaaagt aaagaccaat
    25081 tccagaaagt actccaacta taaaagaatc taaaatctta cctgtaaagt atttaccaat
    25141 atttaaattt aagctttgac atagttctat tataaagtct ccatattttt tacctaggga
    25201 aatataaact actttttttg taaacagtaa gaatttttct ttttctaata atatatagaa
    25261 acaaattata aaacctaaaa gaaattgtac tataaatttt ccaactgaaa atgtagtgct
    25321 aaatatccca ccaagtgaac caataagcaa gttactaaat ttaggcatta cactcataat
    25381 tttgtcacca tactctttta atgtattagg gtcaactgat tgtaaactct tacctaagtc
    25441 gaataagaat tgctctgttt tatctatgta tgtaggaatt tgagcaacta aatcagctaa
    25501 actatttact atggatggaa ctgtaaataa tataaaggaa attagtataa ctatgagtac
    25561 accataagta aggagtaacg aatatattct cttaaaattt aatttacttt ctaagaactt
    25621 tactagtggg ttgaatatat atgctaatac aaatgctatt ataaatggtg ttagtagtga
    25681 cattaataaa cttatcactc caaaaaaata tttgtaatta tcaataactt taatcaagat
    25741 atatgaaaca actacagtga gtacaatatt tagataaatt tttttatctt gcaaaataac
    25801 acaacctttc ttatatttat taaatttaga tatacttaaa tctaagttaa agttaatatt
    25861 tatagcttat tatacaataa aaagcagtat taatatagta tgattaatat gaaattataa
    25921 atacgttaaa actttatgct tatagctaaa ataataaaaa ttatttatat tatgtttata
    25981 tataatctaa aatgaaaaaa agtggtgcct ttgattaaac taagttttta taatttaaat
    26041 tttgtacaat aagctatctt ttattattct ttaaaatata tatttcattt aattatgaca
    26101 aataaagata aaaattaaat attttagagg tgattttatt tagatataga attttagaat
    26161 aatactatac aaatgtattg tattattatt tttatatcaa aaatagtaat aaagtctata
    26221 tacatttaga aaatactgtt taaaaggagt aggatttatg ataaaaaaag agatatctaa
    26281 ctttagagga agtagtgatt atgtagtatc accagaattg atggcatcag ttaatgttgc
    26341 tattgctctt gaaaagccac ttttgattaa gggcgaacct ggaacaggta aaactatgct
    26401 agcacaagca atttcaaatg aattaaaaaa agatttagta atttggaata taaaatcaac
    26461 tacaaaagca caagaagggc tttatgtata tgatactgtt caaagacttt atgatagcca
    26521 atttggaggg gaaggtgtag atgatattag caagtacata aaatatggta aactaggaga
    26581 ggcctttagc tcaaatcaac aagtaattct tttaatagat gaaatagata aggcggattt
    26641 agaatttcca aatgacttgc tttgggaatt ggataaaatg gagttttaca taaatgagac
    26701 aaaagaaact gtaagagcta aacaaagacc aatagttatt ataacttcaa atgcggaaaa
    26761 agaacttcca gatgcttttt taagaagatg tatatttcat tatatagaat ttcctgatag
    26821 agacatgatg gaagaaatag ttaaagtaca ttttgataaa gtagaagaac acctattgga
    26881 acaagtaatg actacttttt attggattag aagtttaaag gacatacaaa aaaagcctag
    26941 tacatcagag ttaatagact ggatacaagc attaactttg agtggaatgc ctattgaaaa
    27001 aatagaaaaa gaagttcctt ttgcaggaat actacttaag aataatgagg atattgaatc
    27061 tatgcaaaga cacttatagt taataggagc tggataatta tgtttattga atttttttat
    27121 ttattgaggt caagaggatt aaatatatct ttaaatgaat ggatgacttt aattgaagca
    27181 ttggataaag ggctgtgcta ttcaaacttt tcaaattttt actatctttg caggatgatt
    27241 ttaataaaaa gtgaaagtga ttttgataag tttgatgcag tgtttttgga gtattttaaa
    27301 ggtatagaac accaagaaga aattccagaa gagattatga attggcttaa aaaaccagat
    27361 atagatttag aagagtttga aagattggaa caaaatccaa atataaatct tgataaatta
    27421 agagctaaat tggaggaacg aataaaagaa caagactctc ctcataatgg tggtaattat
    27481 tggataggca caggaggcac ttccgagtta ggacattcag gaaaagggca aactggtata
    27541 cgtataggtg gaaattctac ttatggtaga gctgttcttg aagttgcagg agaaagaaaa
    27601 tacagagatt ttagagatga tgaagtttta aatatgcgtc aatttcaagt tgcactaaag
    27661 agacttcgtc aattttctac tagaatagat gctccaaaga cagagcttga tttggataag
    27721 actattgaag agacttgtaa taatgcagga tatttaaagt tattttttga gaagccaaga
    27781 aaaaatacag tgaagctttt attgcttatg gattcaggtg gttcaatgag ggggtatagc
    27841 actttatgta atacattatt tcagtctgta agtaaatcaa atcattttaa agatgtaaag
    27901 atatattatt tccataactg tatttatgat agattattta caacacctga atgttggtta
    27961 agtaaatcta ttaatactga atggatatta aaaaatatag ataaaaacta taaagttata
    28021 attgttggag atgcttctat gtcgccttct gagttacttc atattggtgg taactatcgt
    28081 ggtccatata attacacacc tggtatagaa tggcttaaaa ggtttaagag aaagtacagt
    28141 aaaattgtat ggatgaatcc agaacttaga gatggatggg attcaattaa ttattggtac
    28201 caaactcaaa gaatgataca aagtgaattt aatatgtttc cactgactgt aaaaggtctt
    28261 gaaaaagcat tgaaaaattt aatgctttca agataaagta aatataaatg atggtatgat
    28321 ttattcaaaa ttgtaccatc attatttatt ttttaatata tctattataa attgtataac
    28381 tgaaacttaa aaaattatat agtctaatac attttagact tacacaaaac atatacatta
    28441 ataataattt tagaagtcga ggtgattata ataaattatg aattaattgt aaaatacaat
    28501 ggagatatat tgagattaga agaagaatta ggtgtatcag tagagatact taattcatca
    28561 tatgcaataa taacatcaag taatgaagaa gatgtaaata cacttttaac ttatccagaa
    28621 attgaattta tagaaaagcc ttttatatta cagactcagg atgtgcaaag tttttcaagt
    28681 acaggaataa cggggtttaa aaatagaact ggtttaactg gaaagggaac tataattggt
    28741 ataattgatt cgggaataga ttatactcta cctgtgttta gagatagtga tgggaggtct
    28801 aagatattat attattggga ccaatctatt caaggaaatc caccagaagg ttttagagaa
    28861 ggaacattat atactaatga agatataaat aatgcaatag atggaagtat gtatatacct
    28921 atttcaacaa ctagtttaca tgggacacat gttgcaggta tttgtgcaac tattgcaagt
    28981 gatgccagaa taatagtggt tagagttgga aatatacaga ccgatatttt ttcgagaagt
    29041 acagagttta tgagggcaat taaatttatt ttagataggg cattagaatt aagaatgcct
    29101 gttacattaa atataagtta tggaagtaat gaaggttcac atagaggaac atctttattt
    29161 gaacaatata tagatgatat gtgtttattt tggaaaaaca atatagttgt agcagctgga
    29221 aataatgcag ataaaggagg tcataaaagg attaggcttc aaaataatat tacagaagaa
    29281 gttgagttta tagttgggga aggagagcgt atattaaaca taaatatatg gccagatttt
    29341 gttgatgatt ttagtgtaca tttggtaaac ccatcaaaca atcaaacaca agcaatctct
    29401 ctaacttcag gtgagataag aaataccttg ggtgaaacta gaataactgg ttatttttac
    29461 cctatagcac cgtactctct tacaagaaga gttactctac aattaagttc aaatacacag
    29521 ataactcctg gattatggaa aattgtattt gaaccaatag atatagtaac tggtaatgta
    29581 aatatatatt tgccaacttc tgaaggacta aatagaaata ctagatttct gattcctact
    29641 caagagctta ctgtaacagt tcctggaaca gcaagtagag ttgtaacagt aggtagtttt
    29701 aattcaagaa cagacatagt atctatattt tctggtgaag gagatacaca attaggtgtt
    29761 tttaaacctg atttattagc tccaggtgaa gatataatat cttttttacc aggaggtaca
    29821 agtggagcat taactggaac tagcatggct acacctcatg ttacaggggt ttgttcattg
    29881 tttatggaat ggggaattgt aaatggaaat gatttattct tgtattcaca gaaattaagg
    29941 gcattacttt taaagggagc aaggagatta agtaatcaat cttatccaaa taattcatca
    30001 ggacttggtt ttttaaattt atcagatata gatttgtata ctctatctaa tataaatcaa
    30061 gatttagaaa cggaggatat tggatataga agtattaata agtcatttaa agatgaggaa
    30121 aatagttata agcttataga tggttataat atgcaaatac ataatgactt agagaatgaa
    30181 atttatataa gtaaaaatgc aagtagacaa tcaggaatac tatcaggaat agatgtagtc
    30241 catactcccg aatttgaaga agaactagct gaattaggta tgagtcaaag tttttttaag
    30301 ataagtgatt cattaggtgt actatttata aataatacag actatagtag catacaacga
    30361 gttttacaac tttcttcaat cataagaact gtatcgacta caaagaggac attacttgga
    30421 gaaattaatc gaggtacttt tggaggtgta gttgcaacag aagaaatggg cgtaaatttc
    30481 tttaaaaaca atcctaatat taatataaca ggaagaggga ctctaatatc aattgcagat
    30541 acaggaatag actatctaca cccagatttt atttatccag atggtacttc aaaaatagta
    30601 tatttatggg accaaacaaa agaaggaacc ccacctgatg gtttttatat tgggacagaa
    30661 tatacacgag aagatataaa tcgagctatc gcagaaaatg accctagtct atctcaggat
    30721 gaagttggtc aaggaactat gttgagtggt atatgtgcag ggcttggaaa tgtaaatagt
    30781 gaatatgcag gtatagcaga agattctgag ctaataataa taaaactcgg caagatagat
    30841 ggtttttata atagtgcaat gttgtttgct gcatctcagt atgcatataa aaaagctttt
    30901 gaacttagaa gaccactagt tataaatatg tctttaggta ccagtagctt ggcaggttta
    30961 accaatagga gcaatagtga aaaagcattc tttactagag ggttatgtat aacagcagga
    31021 gcaggaaatg agggcaatac acagacacat acatctggaa taataccaca tgttggaggt
    31081 tctgttgaag ttgaattaga gttaaatgaa gacgaggaag aattatcatt agaactttgg
    31141 ttaaatagac cagataaagc tgatgtaata atagtatctc ccactggtga agaaagtaaa
    31201 agtgttggaa tttcaaatta taataaagta acaggtttat ttgatttaga ggggactgaa
    31261 tattctataa cgtatatata cccaacaact ttttctgggc agcaatttac taatgttact
    31321 ttaaagaatg caaaaagagg tgtatggaag attcgattag taggggttta tattataaca
    31381 ggaagatata acttatacct tccaaataga gaacttttaa aaagtggaac tagatttaga
    31441 gaggtagacc ctttttacac tataaattat cctgctattc aagatgattt aataactgta
    31501 ggagcctaca atactattaa tggtagttta tggcaaagtt catcaagagg accaactatt
    31561 gaagacaggt taaaaccaga tatagtagca ccaggtgtta atataatagc tgcttatcct
    31621 gggaacacgt atgcaactat aactggtaca gcagcagcaa gtgcacatgc agctggtgct
    31681 gctgcaatgt atttccaata tacttttgtt gatggtagat atccaaacca agcatatgtg
    31741 caaaaaataa aaacttttat gcaagctggt gctagaaaag attcaaacac agtatatcca
    31801 aatacaaatt ctggatatgg gcttttggat gttagaggaa tgtttgatgt tttaagatag
    31861 gagggattta tggaaaaatc ttattgtata atttatcaag gtgatataga atctgcccta
    31921 caagaaaatg gaataaatag gtatatggtt ttaaatagtc agcttgcagt aatatatgta
    31981 cctgtagatt ttgatgaaac tattttaaat aatataatac aagttgcttg gtgggaagaa
    32041 tctgaaccaa tgagcagtct aattgaaata actaataatg taaataatgg agaaaccatt
    32101 acaacagcag ctgaaactga ttatatttat gaaaatccat ataatgatat aacaggaaga
    32161 ggaattttat tagcagttat agattctggt atagattatt tgcatcctga ttttataaat
    32221 gatgatggaa ctagtaaagt tctatattta tgggaccaag aagcaaatac aaatccacct
    32281 ccagaaggtt ttatttttgg aagtgaattt acaagaagtg agttaaatat agccataaat
    32341 agaaatgatg gaagtttgag tcaggataat ataggtactg gaactttagt ttctggtata
    32401 ttagttggaa atggaaggat aaattcgcag tatagaggta ttactacaga atcagactta
    32461 atagtagtta aattaaaatc atatacagat acttattatg ctggaaggat aaattatagt
    32521 gtttcagatt ttttagcagc tataacgtat gttactaata tagcaagaac agaaaataaa
    32581 ccactaataa taaatttgac tattggagtt aagtcaagtg ctgtagcaac tacttcaata
    32641 ttagatactt ttaatatatt gagtagtgct ggtgtggtag tagtgagtgg tgcaggaaat
    32701 caaggaaata cagatattca ttattctggc agatttagca gtgtgggaga agttcaagat
    32761 gtaataatac aagatggaga tgactatgct cttgatataa cactaaatac gaatggtcca
    32821 gataaagtgg gagcacagat aatatctcct tcaggtgaag ttagtcatga tataaggtat
    32881 tctccagact tttatatata tagaggaaaa tttaacttag aaaatactac ttatgcaatg
    32941 agatttattt atccatatat tacctctgga aaagaaaatt tggagataag attaagagat
    33001 ataaaacctg gagtatggat tttaagattg acttcagaac ttataataag tggagaatat
    33061 gacatatact tgccaaataa aaatttgata gctccagaca cgaggttttt agaccctgat
    33121 tcagtagcta ctataactat gtatgctgct agtgatgatg taattacagt tggtacattt
    33181 aataataaga ctgatagtat gtggattggt tcttcgaaag gaccaattag aggaagagga
    33241 attaagccag atatagtagc ttcaggtgta gatataatat ccacatataa aaatggaaca
    33301 tataatacag gaacaggaac aggagtgagc agttctatag tcacaggtgt tttagcctta
    33361 ttgatggaat acttagaaaa acaggataat gtaccgagat tatcattgtt tacacaagtt
    33421 ttaaaaacat atttaatact gggtgctaca aaacttgaga tatatacata tccaaatgta
    33481 tcgcagggat atgggatttt aaatttaaaa aatacgattc aacagatagc aaatactcta
    33541 tagataagaa cctatgtaaa attataattg attagtaatt taattgtatc aaatatttta
    33601 gatagagtag aaaaatggta taaaaaataa atatgaaaat taaaaaaaca gttttatatt
    33661 ttgaatacgc aaagtaaata ttttgtatat aaataggtat aaattaagta ttgaaaagat
    33721 atgatgttaa tttaaaaatc attataattt agacttatga attttatttg taaaattgtt
    33781 aaaactatta caaaataaat aatagaggtg atagttttgg aaagtaaaaa ggcaagagca
    33841 ttaaaaggta aagataataa aagacttaaa agttcacttt tagttggaaa tgagtcgaca
    33901 gcagcatggg ctgatgttga aaaattaaaa cctcatagta aagtttcaat accttcaatt
    33961 aagggtgtcg aagaagcaaa agactgggtt gacaatggaa gtaaattata aaattttgga
    34021 aattgaagta ataaagaagt aatgaagata agtatttatt atcattatgc aaggtagaat
    34081 tattatattt taaataacaa tcagtatcaa ttatataaat ttattgacta aaaatttata
    34141 aattggtata attttgttaa ttagcagaaa taataaaaga taaatactgt gaagagaaga
    34201 gtagatataa aatgtagttc tagcgagttg aggatggtga aagctcaata cgaggtttat
    34261 attgaagaac atcttggagt ttctaatcga aagcttattt agtaagtaga cttagacgga
    34321 aggcaccgtt ataggcttta agcattgctt aactaagagg tcattatgac aactagggtg
    34381 gtaccgcgag agtaatagtc tttcgtccct ttatataggg atgaagggct ttttttattg
    34441 aaattatatt taaaagaaat taataacaat tatactagga ggatttaaaa tgcaaaagga
    34501 atttataaca gtaaaagaat tgtacagaga aaaagaacag tacataggga agactgtaaa
    34561 agtagctgga tggataagaa catctagagt atctaaaaat tttggattta tagagctaaa
    34621 tgatggaagc ttctttaaaa atatgcagat agtatttgat gagaaagtag aaaattttaa
    34681 agaggtagga aaattagcaa taagctcatc tatacttgta gagggagagt tagtatctac
    34741 agaaggggct aaacaaccag tcgaaataca tgcaaaaagc atagttgtag aaggggaatc
    34801 agatagttcg tatccactac aaaagaagag acatacgctt gaatatttaa gaacgatagc
    34861 acatttaaga ccaagaagta atactttttc agctgtattt agagtaagat caatagctgc
    34921 ctatgcaata cacaaattct tccaagaaag aaactttgta tatgcacatt ctccaatcat
    34981 aacgggtagt gactgtgaag gtgcaggaga gatgtttaga ataacaacta tggatttaaa
    35041 tgatattcca aaaactgaag atggtaaaat agactatact caagatttct ttggaaaaga
    35101 ggctaattta acagttagtg gtcaactaaa tgccgagata atggcacttt cttttagaaa
    35161 cgtttatact tttggaccta catttagagc tgaaaactct tatacaggaa gacatgcttc
    35221 agaattttgg atgatagagc cagaaatagt ttttgcagac cttgaagata acatggaact
    35281 tgcagaagat atgataaaat atgttataag ctatgtatta gaaaatgctc ctgaagaaat
    35341 ggaatttttt aatagtttta tagataaagg attgttagaa agattaaata agatagtaaa
    35401 ctctgagttt attagaataa cgtatactaa agcagtggaa ttattaattg aatctggtca
    35461 tgaatttgag tatcctgttg agtggggatg tgaccttcaa acagagcatg aaagatatat
    35521 aacggagcaa atatataatt gtccagtgtt tgttacagat tatccaaaag atataaaagc
    35581 tttctatatg agaatgaatg aagatggtaa aactgttaga gcaatggatt tactagttcc
    35641 tggagttgga gaaatcgtag gaggttctca aagagaagaa agagaagatg tattgttaga
    35701 tagaattaat gaaatgggat taagagaaga agattattgg tggtatttag aacttagaaa
    35761 gtttggtact gctactcact ctggatttgg tcttggattt gaaagaataa ttatgtatat
    35821 gacaggtatg tctaacataa gagacgttat acctttccca agaactccta aaaatgctga
    35881 attttaataa ttatatataa taaaacttat ataactttaa gtataaacac taaaatgact
    35941 tgcatattta tctattttag agatatgcaa gttattttta ttgtactata aatatataat
    36001 ttgattactt ttattttgcg atataatact tataggttta tataatagta tgtaactttt
    36061 taataaaatg caacacaatt acgtcccttt tcttttgcag tatatagagc cttatcacaa
    36121 ttacttataa actcatttaa tgttattgtc ttttcaattt tctttgtgta aactccaata
    36181 ctaacagtta cacattttaa aggaacatca tcacgctcaa aattgcagga ctctataatt
    36241 tttcgtaaac attctgattt aagtttagca tctgcctcat tacagttaaa aatacatata
    36301 aaaaattcct caccaccata tcgtatagca tgttcatttt cagaacttgt gaaatctaaa
    36361 attactttgg caatattttg tagacaatag tctccctttt gatgtccata attatcatta
    36421 aattgtttga aataatctat atctatcatc attccagtta taggttcttg atttgcatgg
    36481 ctgattaatt ttttttgtag aatatcttca aggtatctac ggttgttcat tttagtaagg
    36541 tcatctgtca taactttgtc gttaagtaaa ttatttatat gagatatttc ttcatattgt
    36601 tgactaatta aaagtttatc atagtaagta aatacacgat ttctatatag cattgtagaa
    36661 acaaaaatgg caagggatgt tataaaaaat gtgttgacaa tattactaaa ctcattgcct
    36721 ggtatagttt gaatcccagg taagaataaa ttaagaaaca aaaagcatcc tccaaaaact
    36781 attactgatt ctccaagttt taatactgag aaagctgcag ctgctaaaat aatgtaacta
    36841 aatacactta ggtcatttcc acctaactgg tcaagtagag taattacaca accccatagg
    36901 cagaaaaaag tcacataaat tatccataaa tttatataaa acgtacaaca atcctttttt
    36961 ttattccaaa gataagaaaa tacaaacata aagacagaag atacacaaaa tagtgttaca
    37021 tacatataaa aataccattg gcgtcttggt gtggcaaaag ggcctccttc tctagctgag
    37081 attgatatca tcataattat ttgagatatt actattatta tgcaaatgat tttacccgta
    37141 tgataaagat aattgcagag ttctttttca acattttctt tgtgtttttt gtctagagga
    37201 aatccaaaaa acttttttat tttttctaag ttcatataag cctccattaa aaataaagca
    37261 taaaaataag tattcctttc tgtccttaga tacttggaat acttcgttta taatttaatt
    37321 atatcaaaat atattgtgtg taacaatcta aaattgtgat agataaaatt tattagctaa
    37381 tgttgagtaa ctttattaat taatacttta ctataattaa gatttacaga tagtttgctg
    37441 ctgaaaataa agaatagaat aaatttaaat taagcataat aaaatataaa taataaagtt
    37501 cgcattaaca aactatttaa atatcaagac ctgttaaaaa acaacagcaa taaacaaata
    37561 aaatagataa atatatccaa ttaaggtata attaagtttt atatgatata gttatatttg
    37621 ataatttaca atagtaaaac ttggagggaa aaaatgggtg aaaagaaaat aaataatatg
    37681 aattattcac ataataatta ttccaaaaag acaggtgaac caactagaaa aataaaaaat
    37741 agccatatca ctcttaaaag taaagaagaa aaaatttgtt ctagttgcaa taaagaaaat
    37801 aatactaagg ataattactg taaattttgt ggaaatgaac tttatgaaat aacatcatta
    37861 agaccacttg aaacaaaact agacttgaaa tctaaaataa aagagctttc atatcatgca
    37921 aataaaagag gtgtattttt aacaacattt acaaccatat ttatattatt tattattgca
    37981 ttgatattta aggctattat aactattcaa tttaatgata ttagttattt aataaatcca
    38041 gcacatataa tcctagctct caacttgggt caaattagtg tatctatgtc taccatgatg
    38101 ggttctgggt ttataaatgc caatataggt ttgttgatat tacttataat ccctattttg
    38161 gtattattaa tatcaaacct aatttttatg agaaaaagat gtagagattc aaaaactgtg
    38221 ttagcaaatt ctctaggagt tggaattttt tatggattag ttttggctat tttatctatt
    38281 tttactaatg taaaaactag ttcacatagt atgttagaat atggatatgc attagaatat
    38341 agttatgaat tttttagtgt tcttttaaat ggatttgtat tagggtttat atgtacatac
    38401 ataactactt ataaaaaaag ttatgaaaag gaaaatatgt atttatctct tttttcaaat
    38461 tctataagaa catttatatt aggttatatt ttagtattag taatactatt ggtactaact
    38521 atatctgata gtagttactt aaatgaacta gatatgagta gttattcaaa tggattaaat
    38581 ttatttacta tactaccaca aatagctagt tatatgtggg cttttgcaaa tggaatttca
    38641 gtaaccataa taaattcaac agtatcaatg tttactttaa gttcttcatc tttatttgga
    38701 gatactaaat taatgtttta tgcaatggga gcattgtcta tgttaatatt attattaaat
    38761 ggatacaagc taagatttaa gtataataca gatagtataa aacctataat agtatttagt
    38821 atatattatg catttttgat gggaatgtta gctttattta gcacatttat actagatagt
    38881 aatattaatt tctttaatac aactagttat ggagcaactt taataatgca atttaaagtc
    38941 ttacaagcta ttgtaatttc atttgtatat agttttgtga tatctttaat aggatataag
    39001 ctaaactcag ctgattaaat atgattggag ggaacttctg tggaaggaaa tactaataat
    39061 aaagtagatg ataaattttc taaggttaag aaaaagtttg gtagtggaaa atttaaagtt
    39121 gaattatata aagaaaaatc aaaattaaat agagagattg atgatattca agaaaagaaa
    39181 gcaaagatat tcttggaaat gggaatactg acatatcaaa aaattagaga agattctatt
    39241 aatgataata gttttgataa attctgtgat gagctactag aacttgataa gttaatttat
    39301 gaaaaaaata tggaaattaa tgaaatggaa atggcagaaa gtagtgtaac ttgtgagtgt
    39361 gggtatgttg gaaatgtaaa tgataaatat tgtgctgaat gtggtaaaaa atttgaattg
    39421 gaaaatgaat gtgatgattt tatagtttgt ggttattgtg aaagtgagat agatatagag
    39481 gctgaatttt gtccatgctg tggaagaaaa attataatgg atttagaata atattgggaa
    39541 acctatgtat agtatacatg ggttttttta ttgaaattat ttaaatggac ttataacagt
    39601 agttatataa aatgaaaata aacaccaaaa aaatgaaata aaatttcttt taaatgtaaa
    39661 aaacaagcta atatataaaa taaatcagta aaaatataga tgcgagaaaa aaatatgaaa
    39721 aaatattgca aagaaaaagt tttcatgtta ttattaatac ataaatcaag aaaataaatt
    39781 tcagaaacga ggtaatttaa aaaatgctag ataaggtaaa gggaagatta atagtatcat
    39841 gccaagcttt agaaaatgaa cctcttcata gtccttttat aatggggaga atggctaagg
    39901 ctgctatgga aggtggagct gttggaatta gagctcaagg agttgaagat attattgaaa
    39961 taaaaaaagt tactggactt cctgttatag gtattataaa gagaaactat gaagattcag
    40021 atatatatat aacgccaact aaaaaagaag ttgatgaact tttaacaaca gggtgtgaaa
    40081 tgatagcatt agatgctacc aatagagtta gaccaaataa tgaagactta aaagaactta
    40141 taaagtatat aaaagaaaac ggtgttctag taatggcaga tatttcaaat tatgatgagg
    40201 ctatcaaagc acaagagtac ggtgtagatt gcgtttcaac tacactatct ggatatactc
    40261 catatactaa aacattagaa ggtccagatt ttgtattaat ggaaagatta gttaaagatt
    40321 tagaaatacc tgtaatagct gaaggaaagg taaatactcc tcaagattta aaaaaggtct
    40381 ttgagttggg tgttcattca tcagtagtag gttcagcaat aacaagacca caattaataa
    40441 cagaaaaatt tgttaaagca attgaaatta attaaaaatt aatttataaa ttaaaaaatt
    40501 attatattta actatacttg aaaattaaaa ttggaggtaa agatatgaga acaacagata
    40561 tgaagggaat ttattcagca ttattagttt catttgataa ggaagggaat ataaatgaaa
    40621 aagggttaag acaaataatt agacacaata tagatgtttg taaagtagat ggtctttatg
    40681 taggaggaag tacaggggaa aacttcatgc tttcaactga tgaaaagaaa agaatatttg
    40741 aaatagctaa agatgaagtg aaagaagaaa taaaattaat agctcaagtt ggttcagtta
    40801 atttaaaaga agctgtagaa cttgctaaat ttacaactga tttaggatat gatgcaataa
    40861 gtgctgttac acctttttac tataaatttg attttgaaga aataaaacac tattataata
    40921 caataataaa ttctgtagat aatagattaa taatatactc tataccattt ttaactggtg
    40981 ttgatatgag tttagaccag tttggagaat tatttgaaaa tgaaaaaata ataggtgtta
    41041 agtttacagc agcagatttc tacttattag agagaatgag aaaaacattc ccaaataaat
    41101 taatatttgc aggatttgat gaaatgatgt taccagctac agttttaggt gtagatgggg
    41161 caattggttc tacattcaat gtaaacggtg tcagagctag acaaatattc gaattaacta
    41221 agaatgaaaa aatatctgaa gcacttgaag tacaacatgt gactaatgat ttaataacag
    41281 atatattagg aaatggctta tatcaaacaa ttaaattact acttgaagaa caaggtgttg
    41341 aggctggata ctgtagacaa cctatgaaag aagcaactga tgaaatgaaa tcaagagcaa
    41401 aagaaatata cagaaagtat ttttaataaa atacttttag tatgggagga ttagtcaaat
    41461 ggtaggattt acttggatag attttgcaat actagtggtt tacttattgg cagttttatt
    41521 tgcaggattg ttattttcaa aaaaggaaat gaagggaaaa gagttcttca aaggtgatgg
    41581 aactattccg tggtgggtta catcagtatc aatatttgcc acattattaa gtccaatatc
    41641 atttttatca ttagcaggaa attcttatgg tggtacttgg attttgtggt ttgcacaatt
    41701 aggtatgttt atagctatac ctttaacaat aaaatttttc ttacctctat atagtaggtt
    41761 agaaatagat acagcatatg aatacttaga aatgagatac gaaagtaaag gtcttagaat
    41821 acttggggct ttaatgttta taatatatca aataggacgt atgtctatca taatgtatct
    41881 tccatcagtg gttctagctg gtcttacagg aatacctgta aatgtattga tagtagttat
    41941 gggtgtaata gcaataattt attcatatac aggtggatta aaagctgtct tgtggaccga
    42001 ttttatacaa gggatggtat taatagtagg tgttacaggg acattgttct atttaatagc
    42061 aagtataaat ggtggttttg gaacagtaat ggatactctt acaactggac acaagttctt
    42121 agcaagtaat gaagttatgt ttgataaaaa tatactatct acaagtgcat ttataatatt
    42181 tgttggagct ggtcttaata ctttttcatc atatgtatcg agtcaagata tagttcaaag
    42241 gtttactaca acaactgaca taaagcaact taataaaatg acatatggaa atggtgtttt
    42301 atcaatggga cttgcaacag tattttatct aattggaact tgtttattta tatactatac
    42361 tcaaaaccca gatttagctc aaacagttca acaagaccaa gtatttgcat catatatagc
    42421 ttatgaatta ccagtaggta taacaggaat actacttgca gcgatatatg cagcttctca
    42481 atcaacttta tcgacagggc ttaattcagt tgctacaagt tggactttag atatacaaac
    42541 tatcataaca aaagatataa gtatggaaaa gcaaactaag atagcacaat atatatcatt
    42601 aggtgtaggt atactttcta tagctgttgc aatagtatta gcaaatggag aaataaagtc
    42661 agcatatgaa tggttcaata gttttatggg gctagtacta ggtgttttag caggaatatt
    42721 tgtacttggt gcattttgta aaaaagcaac taaaatagga gcatatgttg gattcatagt
    42781 atcagcaatt ttagttgttt atttaaaata tcgtatgcca gaagtaactt cttgggcata
    42841 ttctctaata acaatcacaa cttctgtagt ggtaggtaca atagttagtg caatagaagc
    42901 taaagttaaa gcaaaagtat ctttaccaaa agctgagact actgtttatt atgaaaaata
    42961 atatttaaat gataaattgt cttatagagt gattagataa ataatttagt tactctataa
    43021 gattgtataa catactttgt atataaaagt ataaaaatag attttataat tatataggga
    43081 gatagtgctt atgatatttg gaaatataaa tcatagtaag acatattcaa cattgcatga
    43141 agatttactt agatgttttg aatatgctaa agataattca ttaatagatt atgaaaaagg
    43201 tacttataca atagatggtg atgatatttt tgtgaatatt gtagagtata aaacttgtga
    43261 aaaagaagat agattctggg aagctcataa gaagtatata gatgttcatt tgatgcttga
    43321 tggatgtgaa cgaatagata taaattttat agaaaattta gaacaaaaaa tatatgaaga
    43381 agagggagat ttcttacccc ttgatggtaa aaataatgga tatgtggaac ttaaaaaagg
    43441 tgatttttta gtttgttatc cagaagatgc tcatatgaca gggataaaag ttttagaaaa
    43501 agaaaatatc aaaaaagcta tttttaaggt tttggttaga taatgataat ttatataacc
    43561 actagggctg aaaatagtga tttaactttc agcgattagt gagacttcgt aaattttagt
    43621 tagattacta ttttcagcct tagtttttta tgagaaaatt gaaaataatt aaaagcttaa
    43681 aattttgtaa aggagttaac ttatggaaaa tatagatgta ttcttattaa taggacaaag
    43741 caatgctaga ggattgggaa atccaaaaga gagcgtcatt ccaaatgaaa attgttttga
    43801 atatttgagt actgatgaaa ttataaatat gagatgtgag ctagagactt cagaaggtga
    43861 tggtactata gcacctgcat tttcaaatga atggaataag cttactggaa ataaagtttg
    43921 ctttattcac aatgcaaaag atggttcaag aataaaaaac tggaatcatg ataataactg
    43981 gtttctaaat aacactatag aaaaatttaa tgcaggttgt actaccttaa gtaaacatta
    44041 taatatagaa aataaatatg ttatttggat tcaaggtgaa agtgatgcaa aatatggtag
    44101 tgatgcattg tactataaag aaagtctaaa aaaaattgcg tataggctta aagaagaatg
    44161 tatgattgat aaaatgtttg taagtttaac tggttattgg cttggagaag atgaatattt
    44221 tattagaaca agacgaattg cagcagcaca ggagtctgct tgtagtgaat gtgatatatt
    44281 atgtgtagga agcaaaattg ctatgcaatt tcatgacaga ggattaacta ttgatgatgt
    44341 tcattacact caagaaggcc ttaatatatt aggaaaagac ttgtgtgaaa atatttataa
    44401 atatcataca actaaggaaa aagaattatt aagtgataca atagatttat cagaagcaag
    44461 aaggtatata tacgaattgg aaaagataag taaaaagttt gtttaatata agaggttaag
    44521 tagtattgtc aatttataaa aataatttat atggagatat gttatgaaaa attacgtttg
    44581 tatagatgtt ggaggtactt caataaaata tggatttatt agagaagatg gattaataat
    44641 tgataaatca agtcttgata ctgaagcaaa agaaaaaggt ggagaaggaa tattatctaa
    44701 aataaaagat atagtaaaaa agtatataaa agaaaatgaa ataagtggtg tatgcatatc
    44761 aactgcaggt atggttgacc cagttgaagg taaaatacta tttgcattag aagaattaat
    44821 tccaaattat aagggtatgc aattaaaaaa agaagtagaa aaagagttta atataaaatg
    44881 tgaagttgaa aatgatgtta attgtgctgg acttggtgaa atgtggcttg gagcaggtag
    44941 aggtgcaaca tcttctatat gtttaacaat aggtactgga attggtggat gtattataat
    45001 aaacaataaa ctgataaatg ggtttagtaa tagcgctggt gaagtaggat atatgaatat
    45061 aaatggaagt tcttttcaag aattggcatc tactagcagt ctaattaaaa aagtagcaaa
    45121 aataaaaaat ttgaatgaaa aggacttaaa tggaaaaata atttttgatt tagcaaagaa
    45181 taatgatgaa gattgtttaa aagaactcga taatatgata aaatcattag cagttggaat
    45241 cgcaaatata tgttatgtaa taaatccaga agtggtaatt ttaggtggtg ggattatggc
    45301 acaagaaaag ttcctaaaac caaaaataga caaagcatta aaggaggttc ttatagagag
    45361 agtttacaaa aacactaata tagaatttgc aaagagacaa aatgatgcag gaatgcttgg
    45421 agcattatat aattttttaa acaaaatata aagaatagaa gggtttttaa tgagtatttt
    45481 agaacaattg gaatcaccaa cttttaaagt cacaaaatca gataaattat taatagctta
    45541 tataaaagaa aatatagatg atgtatttta taaaccaata tcacaaatag ctaaagagag
    45601 caatattggt gaagcaacta taactagatt tgtaaaaaaa atgaatttta atggattaca
    45661 ggattttaaa gttactttag cacaagaaat atcaactatc aataaaaaaa atattataaa
    45721 taaaaatata caaaatgatg agccagcttt ggatacagca aaaaaacttt taagttcaaa
    45781 tgtaaccact ttagagaaca cagtagagat aatcaatagt aaggatgtac atgactgtgc
    45841 aaggcttata ataaatgcaa agaaagttta cttcataggc attggatatt ctggtataat
    45901 agcacaggat tcaaactata aatttatgag aataggcctt aattgtgtaa gttttgatag
    45961 cagtcatacg atgataatga tgtcttccat aatggaagaa ggagatttaa taattgcaat
    46021 ttcacattct ggtgaaacag aagagattat aaaaactgta aagcttgcaa gagccaataa
    46081 tgctaaaatt atatcaatta ctgaaaataa aaattctgaa ttaaaggata tttcagatgt
    46141 acacttatct tatgtatcag gagaaacagt actggaaact ggttcaatat cttctaaatt
    46201 agcacaattt ttcattattg atttagtata tacacaggta gtaaaagaac tttctaatga
    46261 agctattgaa aggaaaatta aaactacaaa tgctataaaa ttgtttaaaa atgaataaaa
    46321 taagaaattt gtaatgtttt atagagctct cttaaaaatt taggaatgga gagatattac
    46381 atgtctaaat taaaagatta taatattgat aaagtaataa tttttaataa tttaagtact
    46441 aaaacgaaga atcaacttaa agaaaaagct aaactaaaaa gattacaaaa aaaagaaatt
    46501 ttattttatg aaaaagatag cttagacagt gtttatatac ttttagaagg aaaggtatct
    46561 atttttaaga taagtgaaaa tggagagaga aaagtaattt tcatattaaa tagtggggaa
    46621 gtcataaatg atattacatt tgactcttct aaaaactcca ctgttggctg tgaagcattt
    46681 gaaaattcaa ttgtagctta ttatagtatt gaagaatttt tagaaattat gcaaaatgat
    46741 tttcaactta caaaggatat tatttcttat atggaaagaa gaataagacg tttatataga
    46801 cagttgaaaa attctatatc cataaaagta gataaaaaac ttgcagcaaa attatatagg
    46861 ttaagtagag aatttggagt ttgctgtgga gaatggactt tactaaatgt aaatattaca
    46921 gttacatatt tagctgatat gcttggctgt aaaagggaga ctgtttccag aatgataaag
    46981 gtattgcaaa aagaagaact tattaagatt gataataaag gtttttatgt taaagaaact
    47041 gaattatcaa ggtatttcaa aaataattaa ttatgattaa gtaaaagtat tattagaatt
    47101 ttaattaaat aaaaatatta ttaagagaat ctatttatag attctttttt attgtctaat
    47161 ttattaattt ttattttacc ctattgaatt gtataaaaaa gcaaataaga ttctttatta
    47221 ttcaaaaaat tgagtagata atagttttat tgtatttaat gattgtatct aagtgattag
    47281 atttgaaatc gaataatata gataataaaa aaatattaac agagattagt aaactccatt
    47341 aatatttttt ttattatttt tgaaactgtg ataattatca cagaagcata gaaaataaag
    47401 tgttaagatt taaacaagat agcaagtaag taaaactaaa atataagaaa ggtgataaaa
    47461 atgaaactaa aattagattc atctaaattc aatgaaggtc ttaattatct aaaaaaagac
    47521 tacaagatat ttgcaccagt tttaatacca tttaaaggta ctttttcaga taccgatgtt
    47581 ataagataca aggaggtaaa cgctttcgaa gaaatggaat ttgctaagaa agcaaatttt
    47641 tcaccaaaag aagttgtact tcccataaat caagtattgt tttattttac tgaaaaagag
    47701 tttaaggaaa gcgatttaga caacaagaaa attttaattt tcttaagagc ttgtgacata
    47761 aatggtataa aaagacttga tgaaatatat ctaaataatg gcgaagaaaa agattatttt
    47821 tataaaaata ttagagataa agtaaagttt gcacttgtag ggtgtaagga aagttttaga
    47881 aactgttttt gtgtgagcat ggattctaac aaaactgata attattcaat tggattaaat
    47941 atagaaggag atacactgta cttagatata aaggatagtg aatttgaagt atttaatgga
    48001 gaagcaactg aatttaatgt tgattatgta actgataatt taatatctgt agatgtgcca
    48061 gagaatattg attcaaatga aattatagga aattcaatat gggatgaata tgatacaaga
    48121 tgtataggat gtggtagatg taattttgta tgtccaacat gttcatgttt tacaatgcag
    48181 gatattttct ataaggaaaa cgaaaatgta ggtgagagaa gaagggtttg ggcttcttgt
    48241 caagtagatg gatatacaga tatagcaggt ggaaattctt ttagaaaaaa acaaggtgaa
    48301 agaatgagat ttaaaactat gcataaaata catgatttta aaaaaagatt cggatatcat
    48361 atgtgtgttg gttgtggaag atgtgatgat gcctgtccgc aatacatatc attttcaaag
    48421 tgtatagaaa aaataaatga tttagtaact agtaaggagg aagtataaat gaacccatat
    48481 ataccagtaa gtgcaaaaat actagatata gttaaacata ctgataaaga atggactttt
    48541 agagtaaact gcgatacaaa aggtgtattg cctggaaagt tttatgagat atctatacct
    48601 aaatacggtg aaagtccaat atcagtatca ggatatggag aggattatat tgactttacc
    48661 ataagaaatg taggaaaagt aactagcgag ttgtttaatt ataaagaagg agattctttt
    48721 tttataagag gtccttatgg aaatggattt gatgtatctc tttatgaagg aaaagaaatt
    48781 gtagtggtgg caggaggaag tgcattagcc cctgtaagag gaatagttga atatttttac
    48841 aataataaag aaaaatgcga aaagtttaaa ttaatagtag gatttaaatc accaaaagat
    48901 attttatttg cagatgattt aaagagatgg agtaaaaaac ttgatatttt agttactgta
    48961 gatggagcag aggaaggata ttgtggtaat gtaggattgg taacaaaata cataccagaa
    49021 ttggatatga aagatataaa caatacttct atagttgtag ttggacctcc aatgatgatg
    49081 aaatttacag tagaagaatt tttaaaaaga gatttagatg aaaagaacat ttgggtttct
    49141 tatgaaagaa aaatgtgttg tggaataggt aaatgtggac attgtaaaat ggatgatact
    49201 tacatatgtt tagatggacc agtatttgat tattcatatg ctaaaaatct tattgattag
    49261 ggggcgaagt ttgtgataag agatttaaat accaaaaaag taatgaaaaa tgcttataga
    49321 attacaaaaa caaaatatga gacttcttta agagttagag tacctggtgg tcttattgac
    49381 cctgagagtt tagctgtagt ttctaaaatt gcaagtgagt acggcaatgg acaggtgcac
    49441 ataactacaa gacaggggtt tgaaatatta ggaataaata tggaagatat ggaagaaata
    49501 aataaaatta tacaacctgt tattgaaaaa atgaatataa atcaaagtga gaaaaacgca
    49561 ggttatccag cagcaggtac aagaaatata gcagcttgta taggaaataa agtctgtcca
    49621 aaggctcaat ataatacaac tgaatttgct aaaagaatag aaaaagctat atttccaaat
    49681 gatttacatt ttaaagtggc tttaactggt tgtccaaatg attgtataaa agctagaatg
    49741 aatgactttg gaattattgg tatggcttta ccaatatatg aaaaagatag atgtgtaaat
    49801 tgtggagcat gtgtaaaaaa atgttctaaa atatctgttg gagcattaaa aacagaaaat
    49861 aataaggtgg taagagataa agataagtgt ataggatgtg gagagtgtgt actaaattgc
    49921 ccaacaaatg catggactag agatgagaaa aaatactata gattagctat aatgggtaga
    49981 acaggaaaga aaaaccctag actagcagaa gattttcttt tatgggtaga tgaggacagc
    50041 ataataaaga taatacttaa tacttataga tatgtagaaa agtatataga taaagatgca
    50101 ccaggaggaa aagaacatat aggatatata attgatagaa caggatttat ggaatttaaa
    50161 aaatgggcac ttgaaggtgt agagcttcca gaaataacta aaatgtacga aaacatatac
    50221 tggagtggaa ttaaatatct ataaattgag taaaacatat atttgaataa attaaaattt
    50281 aatagaagga agagggaatt atgcataaag aaactttgga taaattaact aatgcagcta
    50341 taaataagat aaatttatta aacacaagta aagtaaaata tttggtatct tctgcgtttg
    50401 caggacttta tgtaggtata ggtatacttt tgatatttac tattggagga cttttgactg
    50461 atgcaggttc acctatgact aagatagtaa tggggttatc atttgcaata gcactaagtt
    50521 tggttataat gacgggaaca gagttattta ctggaaacaa tatggttatg tctgctggta
    50581 tgttaaataa aggtgtaagt ataaaagata cttctaaaat atgggcatac agttgggtag
    50641 gtaatttaat cggagctttg gttttaggca ttatatttgt aggaactggt ctagtagata
    50701 aaggacctgt agctgaattt tttgcaaata cagcagctag taaagcatcc atgccattta
    50761 cagctctttt ctttagaggg attttatgta atattctagt atgtgtatca gtgttgtgtt
    50821 cgtttagaac taatagtgat actgcaaaaa taattatgat attcttatgt ttatttgctt
    50881 ttataacatc aggctttgag catagtgtag caaatatgac aatttatagt gtttcattat
    50941 tttcaccaac aataagtaca gttactattg gaggagctat ttataattta gtagctgtaa
    51001 cacttggaaa tattgttgga ggagctttat ttatgggtct tggaacttat atattaggta
    51061 aagaaaagct taattaaatt tattgtataa attataactc tcttgataaa tgcattttta
    51121 gtattattga gagagttatt tttatatttt tgaaaaaata tttgaaacaa aaaaaatatg
    51181 ggagcatacg aaaatatatc ggttatatat aaaaaaaata cgtttatata tgaattatat
    51241 agttctaaat ataaaaaatg ttaaagtcct accgtaaaaa agcgcatttt gaataagata
    51301 acaaatatga taaaattggt cttgttgaaa tttttagggg ggatatgatg acaaagaaac
    51361 tagtaatatc aaaaacaaag ttgtttattt ttataatagc atttatttct atatttatat
    51421 atttatttgg aagtaaaaat acacttatag gtgtaggtat agtaacagct atgctaacac
    51481 tcttggaaag agatttaact atttctccaa ttaaaaattt actgaagtat ttagcaataa
    51541 atataatctt aggaatacta tcattttttg cagtacaaaa tatgtattta ggagttttat
    51601 taaattttat agcattattt ataatagggt atgtatttag ttatgactta aaaagagcag
    51661 tatatgtacc ctttggtcta atgtatatat ttatggtaag tatacctgta ggaaaaagtg
    51721 aatttcctat gagattgtcg gctttagctg ttggagcagt tataataatg attgctcaat
    51781 ttgttatgaa tagaaatagg atgaaaaatg tcggagataa agaactgata tctatatgtg
    51841 atgaattatt agaaaaaatt agtcttttaa aaaatactat taatgatgat agttctataa
    51901 ttaaatctag tatgagaaaa atagatagct gtaattatag aataaattct atatctaaaa
    51961 atttgaaaat ggttattttt gataatagaa aagatgactt ttatatcagt attagaggta
    52021 tagacataat gaatatttta ttttcattag aaagaataag tttaatcctg gaaagataca
    52081 aaaaggatag taaagaattt gaagatgaag atataaaaaa tattttagaa gaaagtagca
    52141 taaatagtaa atcagatgtt ttagttgtag caacgaaaga aataaactat attaagatgt
    52201 gtttagaaaa taaagatacc ataactgata aagagatatt aggatttaga gattatgtta
    52261 ttgctcagga tactaaaaat ataaatttaa aagaaattta tagtgtttta gaaaatttat
    52321 atgagttttt agtagattat aaaaaagtaa aatcaagaga cgaaaagaaa gctgaaagaa
    52381 aatcaaagat acctcatgaa tttaaacgac tatcaatata taagaaaaac tttaatttaa
    52441 attctataag attttcttat gcagtaaaga ttgctttagc tacagctgta gcaggtttta
    52501 ttatggatta tttccattta agagatggaa gatggataat gttaactgtc ttttcattaa
    52561 cacaacctta cgcagaaaat tgtatacaaa ggtctagaaa aagaatagaa ggtacattta
    52621 taggagctgt aatatttatt gtattatttt caataataaa agatagtaca ttaaggtcgt
    52681 taatagttct tttagcaggg tatataaact cttatgtagt tgattataga aaattaatgg
    52741 tatgtgtaac tgtttcagct cttggttcag cagtagttat gggagaccca aatgttttaa
    52801 caataagcag gatttcatat gtagcattag gagcaattat tgcattaata gtaaataagt
    52861 ttatattacc atatgatgct aaaacaggct atcaacatgt tatagaaatg tataaaggaa
    52921 tagttaaaaa tataattgat gaagtcaata agtctataga aaatgtagct gatgtttact
    52981 atataaaaaa tttattattg ataccatcac ttattgaaga tagacttatg ttgataaatg
    53041 ctatatataa agataaacat caagaggatt ttttagaaaa tcagaaatta ctaataagta
    53101 atatgtataa tctatatata aatgttaata aaaataaaat aaaagatgaa gatgttgaaa
    53161 aaatattgag agataccaat tatatttcaa attacaatgt agataagtat gatgaaggaa
    53221 gaagtgtaat tttagagagt attgtaaata ctaaaagtct aggtgacaag ataatatgtc
    53281 taaacttact gcaaactcta aatggtgtca aagaaatgta tagaataagt aatataacta
    53341 aagtttcaat aaaagaagca gcttagatat taaattatag aatagccata tatttaaaat
    53401 aaagtatatg gctatttgtt ttataaaata ctaaaagaaa ataatatata aaaaacaaaa
    53461 aacatatatt tatgaatttt atatgaaaat agttaaaata ttgatttttt tcattggttg
    53521 aaaaaacaat ttacttagga taaactataa tagtattcaa atattatggg ggttagattt
    53581 atgagtaaag atgtaaaggt aaagcgtaat aagaaatatg atacatttag tataactatg
    53641 gaacttgaga gacctttact ttatgatgag gttgagaaca aagatgataa aaataataat
    53701 agaaaattta acataaagaa taagatattt aagggaatag gtatactatt tgtattgatt
    53761 ttgcttggct ttttcatatg gataaataaa acatatgaac ctcaaaagct ggcaaaagaa
    53821 gctctagtca gcaatagtaa agttgaagta actgtaaatg aaaacatttc atttacacca
    53881 aaaggaagaa aagtttctaa aggtttaatt ttgtatccag gagctaaagt agaaatagaa
    53941 tcttatgctc cacttgcaag aaaaatagca gaaagtggat atgaggttgt aatcgtaaag
    54001 atgccactta atctagctat acttggaact aataaggcac agaaagttat ggattcttac
    54061 aacaacatag aacattgggt aataggaggt cattcattag gaggagttgc agcatcaaat
    54121 tttgcacgtg ataataaatt aattgaaggc gttgtatttt tagcttctta tccaatgggt
    54181 gatgagttga aagaattagg aaaaaaagtt atatctatat gggggagcaa agatggagta
    54241 gtcaatttta aaagtcttgt agaatcaaaa caaaaacttc ctgatgatac aacttatgtt
    54301 gagattgaag gaggaaatca tgcacaattt ggagattatg gaaaacaaaa gggagataat
    54361 gatgctatta taagtcaaga aaaacaactt aatattactg ccaatagtat cattaaattt
    54421 ttaaagaata tatcttaaac taaaat
//
LOCUS       DACTZW010000020        53876 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.020, whole genome shotgun sequence.
ACCESSION   DACTZW010000020 DACTZW010000000
VERSION     DACTZW010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 53876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53876
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.020"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(<1..1161)
                     /locus_tag="JAM15_06215"
     CDS             complement(<1..1161)
                     /locus_tag="JAM15_06215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HAT6797852.1"
                     /translation="MSKNIYVKETYEWIRVGNGENELTEIEYEKLLKYLENNNDVLKS
                     NIIDIKYKKLRFINYVGIICFENVILEILPKLSLSDNLVKDREILLQMLSICNKIPIT
                     MNEKIRLSLKNYNLLNFFVMYFIESMQTQMKKGIYFEYINKIENLNVMRGKILLSTYA
                     KEKGISPMKIRCEYDEYSENNFLNQVLKKACISILCRINDNSIQGKIKKILSYFQNVD
                     LIYIDRKKLLDYKFYKNNDRFKDCYLLARLLLLNLSMDNSQNNQEAFSILFEINTLYE
                     EYIGILIKSIWDNSFRETYIQDKSKFLLKNEQTGKKNFNLRPDIVLYDLKNEYEIIID
                     TKWKAIEVDSNVFYRSSDIYQMYAYITAYENAKRCILLYPCIQKDKNYSSWKL"
     gene            complement(1154..3088)
                     /locus_tag="JAM15_06220"
     CDS             complement(1154..3088)
                     /locus_tag="JAM15_06220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAT6797853.1"
                     /translation="MSENIRGTEYWLMEEFFYQETDTPQIFREESIIALGFDIKINLK
                     KVFSMGKKSEKYINENCNDKDFIKKFMSIKKGDYFLYKAYQNIEEKVKCNVSIGIVEE
                     DFENGYELSHILGHTLPVKWMHNFDTVSNCKVYTSEFYKLNNNDISSYLEIIKSQDKK
                     LLRKRIEESENNKWYLKNYYYKNVDKCVDDEELFIQPINLEQLESLKNIKTDDYILLY
                     NSEKVICENDHTMKSLFGVYQVMEGFDKEKVSALDGGYFFPVRWIEYEKENIDGNAWV
                     IFENNSIVEKYVKRFTNKMPLNTILYGPPGTGKTYNTKQMVYNLVSETSLRNKYYTGY
                     LDYKNNVEFCTFHQSYGYEEFIEGLKSDGEGNFKPEDGILKDISIEACYNALKFEKKM
                     SFELEKDSLTLETIKDRKKKLVLENIEYSESFNFEESENYVLIIDEINRGNVSKIFGE
                     LITLLEDDKRLTKSNQTIVKLPYSKEKFSLPPNLYIVGTMNTSDKSIALLDIALRRRF
                     NFEEIMPDYDLLSIVDGIDIRKMLYTINKRIEFLYDRDHVIGQAYLLAVENINDIVVV
                     FRSKIIPLLQEYFYYDSEKVGLILGGIGRNEKDKYIVYKEKLIASELFKNNNASIMES
                     KVNYCIKQNISSEELKNIYE"
     gene            complement(3117..3839)
                     /locus_tag="JAM15_06225"
     CDS             complement(3117..3839)
                     /locus_tag="JAM15_06225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein"
                     /protein_id="HAT6797854.1"
                     /translation="MENFNKNAKIIGIGAEGINIINEVEEKIKANMDIEKININQEIE
                     KEYVRSLLDGVDILFLIYSSEDKHIRDIIKAVSYMSNERRVLSIGMDCSEKENKEDLE
                     LGREFKINNDSIFKFVDLMNIMVESISDSCMINIDITDLKEAIVGDKGIKYSFGEFED
                     TKSYSEIADILFDRMEYIGEEFISKKGIVFVEGSPEFSIMELNDLISNIQSKVEESYE
                     VIFSLYIKENLNGNIRVGLLYN"
     gene            complement(3889..4875)
                     /locus_tag="JAM15_06230"
     CDS             complement(3889..4875)
                     /locus_tag="JAM15_06230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HAT6797855.1"
                     /translation="MSKVKRLTDVWIYINDKQKFTIKELSEEFNLSAKTIQRYLKELN
                     KMGLPIQAEQGRNGGYRVLNNSYIPPVIFTEKEVMIILFALKSLQIYNYKLMEIEINS
                     IMRKVSYERKSSIKVGIENIKRYIGFVANDTNDGDFKSSNVTEFFRASSESLILNIKY
                     KCGNQILEKNVCPIGIYLNKGAWFSPAYDCKSDKIILVHIDNIIDIKRTGESKKIHIN
                     LEEWLHEVYNNLYGNSSTTKKFGEIIYLNVLLTKEGVSKIKDSSWNLDMELNEDGSGI
                     ISTFIKVEDIDCYASILFFIGNNAKVIEPKFLNKLLYDKANELRYFYEENMV"
     gene            complement(4932..5432)
                     /locus_tag="JAM15_06235"
     CDS             complement(4932..5432)
                     /locus_tag="JAM15_06235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HAT6797856.1"
                     /translation="MRKNSINIALTAAITAIYAVLTLSLGFISYGPIQFRVAEIMMLL
                     AFLDKGYIVGLTLGCFLANVIGPYGVPDIIFGTLATFISASMIYITRKLGKQNKSTLV
                     IASLWPTVINSIVVGLMLNVFFGLPLILSMIQVGFGEFVVVTIVGVPFFCFLMKKYKN
                     VINIKF"
     gene            complement(5718..6029)
                     /locus_tag="JAM15_06240"
     CDS             complement(5718..6029)
                     /locus_tag="JAM15_06240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797857.1"
                     /translation="MAGNLNNMRAVNNFRGDKNILECLVSFEGRSISQRKVRVFFKEK
                     QNQIEIDFAEEEISKLVENVVLNTSYQEMLYDEIEKQLEIDCIGTWMILSKLKDGSRV
                     H"
     gene            complement(6169..8433)
                     /locus_tag="JAM15_06245"
     CDS             complement(6169..8433)
                     /locus_tag="JAM15_06245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HAT6797858.1"
                     /translation="MNIVGKGIKKIDGMSITTGKPVYTDDLSAKNALVVKILRSPHAY
                     AKIKDIDTSKAEMVDGVECVLTYKDVPKSRFTLAGQTYPEPSPYDRLILEDVVRYVGD
                     EVAIVAAIDEKTAIKAMNLIKVKYEVLTPVLDFEEAIGNKTMVHDEDRHCNFDIGMQR
                     EKNIVSHHDYTKGDVEKVLSNCDVVIEETYYTQAQAHAMMETYRAYNYLDHMGRLVVV
                     SSTQIPFHVKRHLSRALEIPASKIRVIKPRIGGGFGGKQTACVEIFSAIVTLKTGKPA
                     KIIYDRKETFNCSTSRHAMRLKVRLGATNDGIIKAIDIKALSDTGAYGEHASTTIGLV
                     GEKTLPMYNKVEATRFIADVVYTNKMPAGALRGYGASQGCFAVESTINMLANKLKMDP
                     TDLRLKNVVTEGETTFAYGKTLNSVDLIKCINKGKELIGWNEKYPCKHLDNGKIRSVG
                     MAITMQGSGIQGLDKSSAEIKLNDCGDYTLMIGSTDMGTGSDTILAQMAAEVLDTSIE
                     NITVISADTDLVPYDPGSYASSTTYVTGMAVVKAAQDLREKIISAGATKLGVEKDEVE
                     FDGIKLTSKKGSTLLFDIAVDSTIGPDTNQLIGLASHGSPVSPPPFIAGFAETEIDTE
                     TGKVDLVNYVAVVDCGTVINKNLAKIQVEGGIVQGIGMALFEEVRYTEKGSMDTNTFM
                     QYKIPARCDIGNVKVDFVETYEPTGPFGAKSVGEVVINTPLPAIQEAVFNGIGVRINT
                     LPITPEKVFMEMNK"
     gene            complement(8437..8886)
                     /locus_tag="JAM15_06250"
     CDS             complement(8437..8886)
                     /locus_tag="JAM15_06250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HAT6797859.1"
                     /translation="MLVKININGKKKSVDIEPEEYLVDTLRKVGNLSVKRGCDTGCCG
                     LCTVLIDKKPTLSCATLTLRALDKEITTIEGLENEVKEFSEVLVKEGAEQCGFCSPGF
                     ILTVLAMKDELENPTDDEIKHYLTGNLCRCTGYMGQLRAIKTYLEVK"
     gene            complement(8886..9674)
                     /locus_tag="JAM15_06255"
     CDS             complement(8886..9674)
                     /locus_tag="JAM15_06255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007062012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HAT6797860.1"
                     /translation="MFTVMDIVQPDTVEEAYSILNKRKTNQVIGGSAFLRMGKKRIGT
                     GIELSKLNLDYIKEYEDYVEIGSMTTFRTLETSSIIKNNFGRIIEDSVKNIIGVQFRN
                     VVTVGATVFSKYGFSDLIVALLSLDTEVELYNIGRISLEEFLNRDYEKDLLIKIYIKK
                     TNKNASYKSLRNAKSDYPILNVSVSKHMEQFKLCVGARPQKATIAKQASEFLSNNEIN
                     EINIDKAVEIASEELTFGSNMRASREYRKAMSKVLLKRAIMEVI"
     gene            complement(9869..11137)
                     /locus_tag="JAM15_06260"
     CDS             complement(9869..11137)
                     /locus_tag="JAM15_06260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAT6797861.1"
                     /translation="MEASIHTIASNNLLIIFAIVSITGIICSKLSEIIKVPDVVLYLL
                     VGILIGPSFLKFIDIRGFQIENQLILTFGSAFILYLGGKEISLKVLRNVKISVFLLAT
                     LGVVISAFIMQQVIGFTFGISAMTALLAGTIIASTDPATLVPIFNQVKIKDRVKQTVI
                     SESAFNDATGAILTSAVLAVILSNKFSLGENIYELGTMVIVGVLVGLITGILLLKLVN
                     DKPYGIFKDFAPIISVISVVVAYELSTKLGGSGYMSCFIVGIITGNKKNFKIWLSQKS
                     YDADFYVAETLGTICRMAIFIILGSQVNLAQLSKYFMPSVITVLVLMFIARPLCVLVC
                     TLVDREAKWSKSEILFMMWVRETGVIPAALCGIISAMKVPGYEVISSVVFMTILITLV
                     IQGSTTKLVAKKLGLLEEKVINISEKVSTF"
     gene            complement(11478..11639)
                     /locus_tag="JAM15_06265"
     CDS             complement(11478..11639)
                     /locus_tag="JAM15_06265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III"
                     /protein_id="HAT6797862.1"
                     /translation="MKQDKQNEKQSEISKIKQSNDNKLEIAQELHVSKNIGNMLGYRI
                     DKKKMNRPS"
     gene            complement(11788..12870)
                     /locus_tag="JAM15_06270"
     CDS             complement(11788..12870)
                     /locus_tag="JAM15_06270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HAT6797863.1"
                     /translation="MRKLSKREKDFIQYGFLLFLICITTYLVLTTLDIKLIPKIIRLV
                     NKTYIFLGILTIIVYMIIESIVTHLIINAVQKTKVKFIGIKMATMGFYYNLVTPFASG
                     SQPMQIYALTKYDVSLSKSVAIVTNKTVVFQSTVTVFCGILILLNKSLLMEQVHSVKV
                     LITFGMIMNVSMLLGGLLIVFSPKQVKMIAEVLINFLSKFKTFKFLDSKRDRINHYID
                     DYNYSIKIFIKNVRILVLSILLTVLQLIAYFSIVYCVYKASNLRGVSYVHIMTLQVFL
                     YMAISPIPTPGNVGANEVTFFTMFSNIIPKELLGYSVLLYSGFVYYFILIVSGLFTFG
                     THYTLNSWKKEDKVNSNLDKVIEKLN"
     gene            complement(12973..14568)
                     /locus_tag="JAM15_06275"
     CDS             complement(12973..14568)
                     /locus_tag="JAM15_06275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6797864.1"
                     /translation="MSNLSILIKTNIINEFKLNALKKADSREKQKIMGMILSVVIITG
                     LLIFYVTSISLSLVDILKQINQMEMLLIFGFGLSTLTTIVTSLYKTSSYLFQAKDLDL
                     LTSLPIKESTVLASKILMLVGANYLFSSICMIIPAVVYFFNSDVSITYFPYLILLFLA
                     LPLLPIVASSIIFMFIGQISSRIKYKNLILIIGSIILMLLYTLLMTRLNSMSVEMLKN
                     SVSISETIRKIYPPIYYFVDALKTGSVVSFLAFIAISIIPFFMFVTLFAKKFKDINAK
                     MSEGYKSKTYKFKSQKTSRPSKALLKKEFKRYTSSFIYFLNSSAGLLFLIIGTILILL
                     FGADKVGELLKLNIDFNFIKIQLLGVFFFIIVMNCTTYCSISLEGKNLWILKSSPIDE
                     REIFWSKILMNFLLNAPLSILCLILVSIRLGFEIQFIIVSICLIASFSMFVALMGLLS
                     NLLYPNLDWKNEMAVVKRSASMIITMLVSLAYVIILGGIYVLLGISFLNIYIILASIL
                     TLILDFMIWRIISTKGVRIFKNL"
     gene            complement(14615..15322)
                     /locus_tag="JAM15_06280"
     CDS             complement(14615..15322)
                     /locus_tag="JAM15_06280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6797865.1"
                     /translation="MLKVINVSKSYKNKKVVSSVSFDVNDGELFGFIGHNGAGKTTTI
                     KAIVGIHDFEEGEVLINSKSIKKQPVECKKEMAYIPDNPDLYESLTGIQYLNFIADIF
                     EVAKDKREELIKYYSNKFELNKALGDLISSYSHGMKQKLAIISALIHSPKILILDEPF
                     VGLDPKASFILKEIMREFCDKGGCIFFSTHVLEVAEKICDKIAIIKDGNIIAYGTTEE
                     VKGSNSLESIFMELIEK"
     gene            15574..16719
                     /locus_tag="JAM15_06285"
     CDS             15574..16719
                     /locus_tag="JAM15_06285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAT6797866.1"
                     /translation="MNTFEQLKISSTLIDGLKKQDITSPTEVQSLVIGNIIQNKDLLI
                     NSQTGTGKTLAYLLPIFEKIDTSKRETQALILAPTHELVMQITNQVELLAKNAELSVT
                     SLALIGEVNIQKQIKNIKAVKPHIVIGSCGRVLDLIKQKKLKSHNIKTIVLDEVDNLL
                     NGKNITCIEDIIRTTLRDRQIIGCSASLTDSTIKICDKLMKEFEIIKTKEKSQINPNI
                     NHSYLLGEIRDKFTFLRKALAATNPKKAIVFVNNEKNIEVLVSKLNYHNYKAIGIFGN
                     MEKEDRKNAINKFKLGKAKILITTDLSARGLDIVDVSHVFNLDFPKSKNEYLHRCGRT
                     ARGNRSGNTISIITKKELDIIKDLQKEFSIVITPKTLQNGELIDIIK"
     gene            complement(16833..18209)
                     /locus_tag="JAM15_06290"
     CDS             complement(16833..18209)
                     /locus_tag="JAM15_06290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HAT6797867.1"
                     /translation="MQTTNSSTMQKLFPILTNKNVDMKKEIIAGVTTFLTMAYIIAVN
                     PNILSETGMPAGALVTGTCLAAAFGCILMGVVANLPFALASGMGLNAFFAYTVVLQMG
                     VPWEVALTAVFVEGIIFIVLSVSGVREAVVNAIPKNMKLAVTGGIGIFIALIGLVNSG
                     IVIGDQATLIKMGRFTPAVIITCVGLIIIAVLDKKRVKGSILFGIVVSSLLAWAFAFM
                     NPEYAQKLGIYLPGGLFKFESLAPIAGKIDLGYVLHPTNIGGFLVVVCTFLFVDFFDT
                     VGTLVGVCSKANMLDEKGNVPNVGRALLTDAVATTVGAGLGVSTVTTYVESSTGVIAG
                     GRTGWTAITVGILFLAAMFFSPVFIAIPSCATAPALIYVGYLMLGTVKDIEFDNITEG
                     VPAFVTIACMALTYSIGDGLTLGILTYVFVNIFYNIFGAKKAEDKKHVSVVMIVLAIL
                     FIIKLWLL"
     regulatory      complement(18303..18405)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            18655..20001
                     /locus_tag="JAM15_06295"
     CDS             18655..20001
                     /locus_tag="JAM15_06295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HAT6797868.1"
                     /translation="MKDLTTGHEGKSIFFFAMPMLIGSLFQQLYNTADSIIVGRFIGK
                     EAMAAVSGANPIMFLLVAALMGVSLGFSILVSQFYGSGDLKKVKATIDTTYILLFIGS
                     ILISILGIVFGGPMLKLMNTPESVFAQSKLYLTIIFSGILFSAGYNSVSAILRGLGDS
                     VTPLYFLIIATILNIVLDLTFIVVLRMGVEGVALATIMAQAVSFIISIIYLNKKHEVL
                     KFKIKGIVYDNKIFKDGLRLGLPSGVQQMLFSIGNMTLQFLVNSYGTSAMAAFGAGLR
                     IENFISLPIMNLGSAVSTFVAQNIGAGENERVKKGIRESIKMTLVLAVTVITLILLFR
                     ENLIALFNTDKDVIKIGSSYLFIIGPFFLFIGTSFVLSSAMKGAGDSMFALISSIVSL
                     WLGRLPASYMLSKFFGTDGIWMGIPFGWTLGLIVTVIYYKKGYWKTKAIVNHRINE"
     gene            20079..21473
                     /locus_tag="JAM15_06300"
     CDS             20079..21473
                     /locus_tag="JAM15_06300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HAT6797869.1"
                     /translation="MGIILKPKQFYMTVIATIILYFSLNYSFNIKFSICLSFLTILIW
                     AVDSVEKTFVALFFVILAFIFNIAPIKVILQFLFTENFYIIILAYIITNAVTKTGVAK
                     IISEKLILNTVNTPKKMILLSYILGILLIFFIPQPFPRVILVSAFYKEFLKEQQITED
                     SKSILLFSIFTASTFTSMFFVNGDTLLNYVVLELGNCNINWGQWAFYMSVPTIITCFI
                     TYFLFIFVFKKELHSIKFISHENLEGNKLHFSYSNLKKEFNLLNKEQKHVFLCLGIMF
                     FMFLTQFIHNINTLIIMSICVLLLLLRKIVGFSTLKEINWKVLIFFIAAFSIGGVLKY
                     SGVVDIMGNYLIKFIPNSSEIISILFLITLTIILNICLGSAVTTSSVVIPLLGSLHIL
                     KENSVTLCLFVYIIVSIQYILPFHHATIMVGHGENLYNSKVIFKYGLTLIPLTYFIII
                     CITLPWWKFIGLEI"
     gene            complement(21595..22269)
                     /gene="fsa"
                     /locus_tag="JAM15_06305"
     CDS             complement(21595..22269)
                     /gene="fsa"
                     /locus_tag="JAM15_06305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HAT6797870.1"
                     /translation="MQLILDTGNVEEIKELCTCLPIDGVTTNPSIVSKEKKNFKQLIN
                     EIGEIIGEDMPIHAQVLSTKYEEILEEALYISSLRKNIYVKIPVTQDGLRAIKDLHRK
                     GVKITATAIFTAHQGFLAAKAGANYIAPYVNRLDNISGDGVAMVSELIKIIDTYKMDT
                     KVLAASFKNAQQVIELMQHGVHSVTVPYDICKSMMNHPLTDWSVDKFIEDWENTFGKG
                     SKTNNI"
     gene            22543..23307
                     /locus_tag="JAM15_06310"
     CDS             22543..23307
                     /locus_tag="JAM15_06310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAT6797871.1"
                     /translation="MFAEERIQAILNILKKEGRVTVKELSSKFNVTEDCIRKDLKNIE
                     KISSIRRIYGGAVLARETLENQDTKDRKEINIPTKKIIAEKAFNLIEDRETIFLDIST
                     INILLAKLLAESNKKVTLVTNMLDILNVVTSKPNNLNIISTGGLLNLSLDGFVGTPTI
                     EFISKYKFDKTFMGSCGVDVFNSSLTTFEIEDGLTKKAIINSSKKVFIVMEDKKFKFD
                     GNFKFAHLEDISSIITEKAPTPDIVDILSEFNVNVL"
     gene            complement(23596..23817)
                     /locus_tag="JAM15_06315"
     CDS             complement(23596..23817)
                     /locus_tag="JAM15_06315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797872.1"
                     /translation="MDRLKRDMKNMKEDLKEGVKKTAYVMKNTAEDLKDDAQGAMVNL
                     EMKKDEMMERYEQKKFSKELEKQMKNEMK"
     gene            complement(24218..25495)
                     /locus_tag="JAM15_06320"
     CDS             complement(24218..25495)
                     /locus_tag="JAM15_06320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HAT6797873.1"
                     /translation="MRRIFDKWEKLSIKYKLFSITTSLLIALALIIYLILYFLLPSYY
                     HEYKIESLQESLKSLVDSSIHFDTYTLEERLYYMAKDQNLAILLKDNQGKIVYGKNEV
                     VILRYSKYMINSLEDEYRTSIPIYTKDAKDGPYTLELVMPLQPIDEANEVIRKLMPYI
                     ISIAILIAIIGAYIYSIVITKPLINIIESEREQEYRRKDFVATISHELKTPITIISGQ
                     IEGMIYSVGKYKDRDTYLKKSYECTQELKDLVNEMIEVSKSEILEKDLKLVSINISEL
                     LNRLVKRQIFLIEEKHMKTILKIEENLEIKADQERITKAINNIINNAIKYSPEESELI
                     IRLYDKNKRISKKTSNQRVVLEIENTGVTIEKRYLEEIFNPFYRIEKSRSRKTGGSGL
                     GLYIVSQIFKSHGFDYSIKNKENSVVFTVEFKN"
     gene            complement(25479..26147)
                     /locus_tag="JAM15_06325"
     CDS             complement(25479..26147)
                     /locus_tag="JAM15_06325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6797874.1"
                     /translation="MNSSILVIEDDSNIQELISEFLSAEGYQVDTANDGLEGIQKFKQ
                     GSYDLVILDIMMPNLDGYGVCKMIRKSSSVPIIFLTALNDEGDQLKGFDLECDDYITK
                     PFSFNLLIKRVEAILRRSNKTINDKFIVFEKLKLDLNTYIAEIDGEPIELTLKEFNIL
                     KALIEKYPQVITREGLLDSIWGYDYYGDTRIVDAHIKNIRKKISLPYIKTVKGIGYTL
                     EKDI"
     gene            complement(26307..28808)
                     /locus_tag="JAM15_06330"
     CDS             complement(26307..28808)
                     /locus_tag="JAM15_06330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HAT6797875.1"
                     /translation="MSSNKVVESYKITGMTCAACAKAVERVTKKMDGVYDQSVNIATE
                     KLKIEYDNSKVNFDDIKQVVEKAGYGIIKEESNKKIDMKIDGMTCAACAKAVERVVKK
                     LDGVESISVNIATDKANIDYDPSKVKLSQIKAAIEKAGYKPIEEVRNKVDVDEDKLRK
                     EREMKSLFVKFIVAIVFAVPLFYIAMGPMIIKPIGPWPLPEIINPMTNTFNYALIQLI
                     LVIPVMIAGYKFYINGFKSLFSLSPNMDSLVAIGTLAAFLYSLYTTLQIANGQIQGMH
                     HHQLYYESAGIIIALILLGKYLESKSKGKTSEAIKKLMGLQPKTAIVLVDGKEVETPI
                     EEVEIGDILLVKPGTKIPVDGVVIEGYTSVDESMLTGESIPVEKNVGSKVTGASINKN
                     GVIKFKAEKIGGDTALAQIIKLVEDAQGTKAPIAKLADTVSGYFVPIVIAIAVVASLL
                     WFLIGGKDIVFVLTIFISVLVIACPCALGLATPTAIMVGTGKGAENGILIKGGEALES
                     AHKVNTVIFDKTGTITEGKPKVTDIVLNNNVKEEYLIKIASSAEKGSEHPLGEAIVKY
                     GEEKNIKFEKVDNFKAIPGAGIQVTINDESILLGNRKLMNDNNIKLGDLEEKSNILAS
                     QGKTPMYIAVDGNLSGIIAVADVVKESSKKAIEILHDMGIKVAMVTGDNAKTANAIAN
                     QVGIDMVLAEVLPEDKSKEVEKLQNQGKFVAMVGDGINDAPALAKADIGIAIGSGTDV
                     AIESADIVLMKSDLIDVPTAIKLSHETIKNIKQNLFWAFGYNTIGIPVAAGILYVFGG
                     PLLNPMIAAAAMSLSSVSVVSNALRLKNFKAYKRD"
     gene            complement(29099..29290)
                     /locus_tag="JAM15_06335"
     CDS             complement(29099..29290)
                     /locus_tag="JAM15_06335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1450 domain-containing protein"
                     /protein_id="HAT6797876.1"
                     /translation="MIRVCPNCSNVDVNKLKTLVGEENVKTGCIGQCRAFKKEAVGII
                     DNELEIKETEAEFFEACKE"
     gene            complement(29438..29677)
                     /locus_tag="JAM15_06340"
     CDS             complement(29438..29677)
                     /locus_tag="JAM15_06340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797877.1"
                     /translation="MEVTKIIIKYFASESDTFIKEEVCNFEELLKWSHKFIEGKKIED
                     VLYIKSKENYKVNVIKSLEIKELEIVRKQQIPPYM"
     gene            29892..31715
                     /gene="typA"
                     /locus_tag="JAM15_06345"
     CDS             29892..31715
                     /gene="typA"
                     /locus_tag="JAM15_06345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HAT6797878.1"
                     /translation="MSQKHKIINIAVIAHVDAGKSTLVDAFLSQSGVFRKNEVVKDCV
                     MDSNDLEKERGITIYSKNCAINYEDYKINIVDTPGHSDFSSEVERVMKTVDTVILLVD
                     ASEGPMPQTRFVLQKSLEFGLKPILFINKIDKKDQRAEEVVNEVFDLFVDLNATDEQC
                     EFPIIYGIAKQGIAKLEMDDDSEDLSPLFKTIVNHVEAYPNYDNEPLQFQISALAYDD
                     YVGRLGIGRIYKGTLKNNTQVAICREDSVVSKGKVSKLSVYEGLKQVEVDEATSGEIV
                     VIAGIPDISIGETICDLDSPLPMEMIKIEEPTLSMNFLVNDSPFVGKSGKFVTTRHLK
                     DRLEKELEVNVGLKVEPLDTTDGYKVSGRGELHLSILLENMRREGYEVGVSKPEVLMH
                     KEDGKLMEPIERVVVNCPEVYSGTIINELNMRKGMMESMSIEGDYVKIEFLAPTRGLL
                     GYRSEFINATRGEGTLVRSFEKFEEFKGEIPSRGNGVLIAQGPGVTMGYSLNALSDRA
                     VMFVDPGVEVYEGMIIGMNSRKDDMVVNPCKNKKMSNVRASGSDDAIKLSPPRIFTLE
                     EALEFIEDDELVEITPDSIRLRKRFLNEHDRLRYNKSRQGK"
     gene            complement(31805..32713)
                     /gene="trxB"
                     /locus_tag="JAM15_06350"
     CDS             complement(31805..32713)
                     /gene="trxB"
                     /locus_tag="JAM15_06350"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HAT6797879.1"
                     /translation="MVDIIVIGAGPAGLTSAIYAMRAGLSVTVFEKNIYGGQVASTSE
                     VENYPAVQKISGVEFSNNIYNQAVAQGVDIQFDEVEEINLEGKVKVVKTSSGEHKAKA
                     VILANGVERRKLGCAGEQEFTGRGVSYCATCDGAFFKDKEVAIVGGGNTALEDALFLA
                     NNCTKVYLIHRRDSFRGEEVLEKSVKARENIEILYSHGVEKIEGEKTVSKIEVKNLKT
                     EEKRTIDVSGIFIAIGLKPNNKMFENVLDLDEGGYIISDESCTTSVEGVYVAGDSRTK
                     FLRQIITAASDGAIAAVQAANYINVE"
     misc_binding    33515..33746
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            33854..35335
                     /locus_tag="JAM15_06355"
     CDS             33854..35335
                     /locus_tag="JAM15_06355"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HAT6797880.1"
                     /translation="MYYSSTRGTEEKVTASQAIIKGISSDGGLYVPSEFPNVKNELIN
                     LVNLTYSQIAFFVLSKFLCDFTEDEIKNCIENAYDEKFDCSSIAPLNKVNDTYFLELY
                     HGPTLAFKDMALTIMPHLLKTSIKKDNLEKDVVILTATSGDTGKAALEGFKDIDKIKI
                     IVFFPEDGVSPVQKLQMKTQTGKNTYVVGIKGNFDDAQSGVKKIFSDKKFNQKLLDNN
                     YILSSANSINIGRLLPQVAYYFYSYMKLVSNSEINLNDKINFVVPTGNFGNILAGYYA
                     KQMGLPINKLICASNDNNVLYDFFKTGVYDKNRTLKLTTSPSMDILISSNLERLLFEI
                     SNRNTDIVNKLLSDLSDKGVYKISDDMEKNLASFYGEYSNEEEVKSTINNVFKNYNYL
                     IDTHTAVAYNCYEKYKKETSDNTKTVIVSTASPFKFSEDVLKSIDCDFKDLDDFAIID
                     RLSSISKIDIPKPIKNLKNAEILHKDIYEKDELKLAIKKFLKV"
     gene            35345..36238
                     /locus_tag="JAM15_06360"
     CDS             35345..36238
                     /locus_tag="JAM15_06360"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HAT6797881.1"
                     /translation="MLEIIVPATSANIGPGFDCLGIALNIYNKFYVEEIESGLEIEGC
                     EDAYKNENNLVYTSMKYFFDRVKPEKIPAGIKIKIHSEVPICRGLGSSASCIVAGVIA
                     ANALSGANLDKNQLLNIASEIEGHPDNVAPAILGNMIVSVTDNENIHYDIIKIPEELK
                     FCAMIPNFKLSTEKARGVLPKEIPYSDGVFNVSRVALLISALLNKNFDLLKVACQDKL
                     HQNYRGTLIENYNDIVEKSEQLNSIGVFLSGAGPTIMSLIKENDDSFVDNMKNYLQKL
                     KSDWEIKELCCDSNGAVLNII"
     gene            36362..37423
                     /locus_tag="JAM15_06365"
     CDS             36362..37423
                     /locus_tag="JAM15_06365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitronate monooxygenase"
                     /protein_id="HAT6797882.1"
                     /translation="MIIKELIIRDLVAKVPIIQGGMGVGISRSSLAGAVAKLGGVGVI
                     SGVQIGYDEEDFETNTINANLRAIKKHISKAKEISNGGIIGINFMVAMKEYETYVKEA
                     VKAGVDLIISGAGLPNKLPSLVKGSNVKIAPIVSTAKAANVILKMWDRKEKTTADLIV
                     VEGPKAGGHLGYSNEELDNIDSIDYDKEFVEILKVANTYGEKFGRNIPVVAAGGITSS
                     SDVKKYIDMGASGVQVGTRFVATYECDAHENFKMAYINASEEDVHIVKSPVGLPGRAI
                     RNKFIEEVKINRPEIKKCYNCLIPCNPKETPYCISQALINAVKGDVENSLLFCGNDAY
                     KIDKLSTVEDVINELISEL"
     gene            complement(37578..38090)
                     /locus_tag="JAM15_06370"
     CDS             complement(37578..38090)
                     /locus_tag="JAM15_06370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HAT6797883.1"
                     /translation="MSDFKEILAEEIKNNPFGLIGKDWTLITAENEGKVNTMTASWGG
                     LGVMWGKDVAFVVIRPQRYTKEFIDNTDKFSLTFFDEDFRKELSYCGKVSGREEDKIS
                     QIGFNIEHLNDTPYFKEAKMAIICKKMYSQKLEPQCFIAEGIDGRWYPQKDYHTLYIA
                     EITNVLVKED"
     gene            38610..39545
                     /locus_tag="JAM15_06375"
     CDS             38610..39545
                     /locus_tag="JAM15_06375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAT6797884.1"
                     /translation="MIRYYKTIDSKLEKLSFFEDGCWINLVEPNHSEINEISNLLNID
                     VESIESALDEEERSRIDVEDNHTLILIDIPVDESDSNSSHYTTIPLGIILTEEAIVTV
                     CDAQTKILNDFIVGHIKDFFTFKKTRFLLQILHKNAAYYLHYLRKINKMTIIIEREIY
                     KSMKNKELVQLLELEKSLVYFSTSLKSNELVLNKMVRTAGIKKYPDDEDLLEDVIVEN
                     RQALDMAKIYGDILSRIMDAFSAIISNNQNNVMQILTVVTLIFSIPTIISGFFGMNVI
                     NMPFSNNPNGFWIILLITSIICIVITFFMSRNKLL"
     gene            complement(39637..41508)
                     /locus_tag="JAM15_06380"
     CDS             complement(39637..41508)
                     /locus_tag="JAM15_06380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HAT6797885.1"
                     /translation="MKNTKFSIKKIKNISNDPKVVHTKGALLEKMGKMESAIELYKSA
                     ALDNYVKSQYTLGNIYESKKQFKEAEKWYSMAYKSGSEDAAFDLGNMYYKLDGYEYAI
                     YWYEKIANLGYLQAQNNLGVCHFKMKDFVRCEKWLKTAADKNLGKACFNLGVLYTFLE
                     KDDEAYEYYKKGSVLLDDDAKYNLAILNGKKKDNKSTVSLYKQLYKSGHMKGCFNLGM
                     IMEINDNLEDAEKYYKKSADRDDVKSEYRLAYVYDRKEELGDAIYYYEKAIEKNHTLS
                     KYRLANLYNRENEIEKAKTYYKMAAEDDITEAKNNLAGIYFEEKDYENAIKYYEDAIA
                     VGCKSSLENLGDLYYQNQDIEKAISYYSRIPNNASCQIKLGNIYEDLNNIEEAISWYK
                     KASENGDTRSSYRLGCIYESLGNTKNARKYFEMASSKNHMNARIHLGRIYFREGKLEE
                     SKMMFDTPANENNVYAQHMVGLIYDMFYKDYVNSKFWYEKARAQGCVESIYNLGQIYL
                     KLNDDAEAEKYYKEGIKYGSKKCEYMLAGLYYKKSLDMYISLANEEYDNCEEIVEGFP
                     NLNIDFDEVLIPPFKLQEEVIDEEEYVPIYILNIKESLDSMLEGLETEMIIDEEHDS"
     gene            41698..42624
                     /locus_tag="JAM15_06385"
     CDS             41698..42624
                     /locus_tag="JAM15_06385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HAT6797886.1"
                     /translation="MNFSNIFIQVAVLFIIILVGYFVRKFNLLDDHCTSKLSTLTMTV
                     FLPSMIISSMQINFDSKMIQKILLLLFTSLIMYIVSIIIAFLLKYILKCNDKKDLGIY
                     QYIVVFSNVAFMGYPVIEAVLGHEAIFYTAIFNLPFNLFSFTLGIYLLSKGSTSRGFS
                     IKSLISPATIAIVIGLFLFVTGLRLPQFINEPLEMLGSITTPISMIIIGSLLANSSAL
                     DCFVNKKLYIVTFIRLLVLPVIVYFILKGWINDKMILAIPVVISSMPAAANTAIMANQ
                     YDSNITLASQCVFFTTLFSVISIPFISILLLS"
     gene            complement(43014..43538)
                     /locus_tag="JAM15_06390"
     CDS             complement(43014..43538)
                     /locus_tag="JAM15_06390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAT6797887.1"
                     /translation="MSKPIDITIRPIRREDAQAFNEIRRTYSVMRNTLALMSDRVDKT
                     EAMLASLGENDYMFVAETNNNGEKDVIGFAGLHVNSSPRLRHSAEIGISVGENYQGRG
                     VGKKLMEQLLDIADNWIMLTRVGLEVIVDNEKGLNLYKKLGFEIEGTKKYAVIRDGKF
                     EDVYIMGRYNKNLI"
     gene            complement(43591..43815)
                     /locus_tag="JAM15_06395"
     CDS             complement(43591..43815)
                     /locus_tag="JAM15_06395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797888.1"
                     /translation="MIIKLTKDNFNFRFKQYEGMFFHAEVVEGMESIRYKITKDKEGT
                     ELKEFGSTHIKDNMIYVPQVEAYIDLNSIK"
     gene            44012..45136
                     /locus_tag="JAM15_06400"
     CDS             44012..45136
                     /locus_tag="JAM15_06400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3810 domain-containing protein"
                     /protein_id="HAT6797889.1"
                     /translation="MSKKTKYFSLILFPIALLLNFIASKVPNIVEKYYSQFIDKIIVQ
                     ILSKVSGIFPFSLYEITMYIIVISIFLFLCCTLSTIFNKKKKLNIFLKNSILNILSIV
                     SIVYFLFVVLWGINYNRIPLETTLINNYNLKNNASIQSKQYSVKELTKLYKFLVIKAN
                     ETRKLTLQDKNGIVKSNTDYNGVINRAQLGYDNILDILPSVSGSYSKPKYIISSNLMC
                     YTGITGIYFPFTGEANVNIAIPDLYIPCTVEHEMAHQRGFASEDEANFIAYLTSIKHP
                     HIDFNYSGYILALNYTASSLSKVDYNAYVDISAGISDSVRRDLKNESEFWQKYEGKIN
                     EISNEFNNSYLKANGVTEGTQSYGKMVDLLLTYYELYPYN"
     gene            complement(45609..46433)
                     /locus_tag="JAM15_06405"
     CDS             complement(45609..46433)
                     /locus_tag="JAM15_06405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797890.1"
                     /translation="MRYKKISSLPILVVALLITGTTTTFSLSTTNSEKTNVYLASTVS
                     TVTKKVSDIQSSKGLVYNENIPLFINNSKIQYDDTPYHWPSNVISLTNSSEKAIMDYE
                     ITCLAYDKNGKPLELYWDAQNVAADGEVGSVGFSPAGVDYGIVTGISPVSPKSYSHTY
                     RKMQQSPPQDIISMFEKQQGKAWVENWLKEWKQMEKEYAKQNAIAPGKNQNDAFLLFD
                     KWKQSTGEHGVKYIISCVKQVTFNDGSIWKNSAYENWLKSFQGKEVSNSVLENYYK"
     gene            complement(46781..47836)
                     /gene="ispG"
                     /locus_tag="JAM15_06410"
                     /gene_synonym="gcpE"
     CDS             complement(46781..47836)
                     /gene="ispG"
                     /locus_tag="JAM15_06410"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004167371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HAT6797891.1"
                     /translation="MSYERRKTREVSVGTVKIGGENPISIQSMTNTDTRDADATIAQI
                     KRLEEAGCDIVRVAVPDIKAAKNIAKIKSSVNIPIIADIHFDYKLALEAIEQGVDGIR
                     INPGNIGSRERVKMVVEKCKERNLKIRIGVNGGSLEKELLKKHGSATAEALVESAMGH
                     IKILEDLDFHNIVISLKSSDIYKTVDAYELISKKVDYPLHIGITESGSVHKGTIKSSI
                     GVGALLLKGIGDTVRISLTGDPVEEVIVGKQILRSLGLLNDKIKVISCPTCGRCNIDL
                     ISVVNEVEEKIGSMEKNITVAIMGCAVNGPGEAREADIGIAGGKGEGLLFKKGEIVRM
                     IDGNKLVDELLEEIEKL"
     gene            complement(48019..49023)
                     /gene="rseP"
                     /locus_tag="JAM15_06415"
     CDS             complement(48019..49023)
                     /gene="rseP"
                     /locus_tag="JAM15_06415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HAT6797892.1"
                     /translation="MTIIAALILFSIIVLIHELGHFIFAKRSGIKVNEFSIGMGPKIY
                     SVKKDTEYSIRALPIGGYVSMEGEDEEQISPNSFGNKSILQRFSTIVAGPIFNIILAA
                     ILLVPVFLYIGSPTTKLGKIMPDTPAQAVGLQVGDKINKINGNSVKTWDEVANIINTS
                     SGGELKLSITRDGSNKVVNVTPKNNNGKYEIGIQPQREKDFLASIVNACKTTVDMTKQ
                     MLTFLGQMITGRVPGGIGNAVAGPVGVIGMVSDAARTGIINVVYLAAVISLNLGIVNL
                     LPIPALDGWRILMLLLEAVRGGKKLDPNKEGMINVVGFGALMLFMLFITYKDILRLFQ
                     "
     gene            complement(49036..50190)
                     /locus_tag="JAM15_06420"
     CDS             complement(49036..50190)
                     /locus_tag="JAM15_06420"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HAT6797893.1"
                     /translation="MKKISILGSTGSIGKQTLDVVREHRDKFEIVAISANSNIELLLE
                     QIVEFKPKYVTVFEENKALKLKEMLPKNIEIEVLAGMEGLKIISSLDEVDVLLTAVVG
                     MIGLVPTLCAIKKGIDIALANKETLVTAGELVMKEAEKYNVNILPVDSEHSAIFQCLN
                     GENKKNIEKIILTASGGPFRGKKKGELVNITKNEALKHPNWSMGRKISIDSSTLMNKG
                     LEVIEARWLFGVEQENIDVVVHPQSIIHSMVQYADSSIIAQLGCPDMRLPIQYALTYP
                     DRMESSFERMNFSKFSTLTFEEPDLETFPCLKLAYECLKMGGTYSSVLNSANEVLVSE
                     FLEDKIGFYDIPYYIEKTLEVHSSISEPTLEEILETDRWSRAYVANLIKK"
     gene            complement(50354..50557)
                     /locus_tag="JAM15_06425"
     CDS             complement(50354..50557)
                     /locus_tag="JAM15_06425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAT6797894.1"
                     /translation="MISYAPLWKLLIDRKIKKMEFVNISGISISVLGRLGNDKSVSMD
                     TMEKICLALDCKIEDVVEIKKGI"
     gene            50897..51475
                     /locus_tag="JAM15_06430"
     CDS             50897..51475
                     /locus_tag="JAM15_06430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797895.1"
                     /translation="MYLLKINQFEKSYDIGIFKNEQSIYKFIEKIPFVKKDNSNFNYT
                     NYYMEFEDIPEYYEVNFNNYLYIITRFSFIPDGTEIFFTWEEIHYWDEKVATEKTFIN
                     GETLVDSYNFPNNEVKDYIQKRESLYIETKKYYEEKGLKIERHALGSEDGEYVELTND
                     SILYLLDIEAVEIREQSKNIEEFLYKYKKRFK"
     gene            complement(51563..53374)
                     /locus_tag="JAM15_06435"
     CDS             complement(51563..53374)
                     /locus_tag="JAM15_06435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HAT6797896.1"
                     /translation="MKKKYNFLIYSAIWLVIIILFIFSLYHSIEHIKIISHTGTIRSE
                     TQKVVKQELNNERNDDLIKRLDNILIKLRTGNGENGFQRCDNKEFQQKLNQMDSIWES
                     MKKEIIKVRNGASGDKLYKLSEEYSVLSNQIVFISEKHSNAKLYSFATALFIYLIFST
                     ISLLIWEYYNKKRFKRIFYTDNLTKIKNQVAFENRAIEILYNASNKEYVLLNIDIDNF
                     KYINDTHGYEYGDKVLIIVAAALSKTFNIKETCARIGSDNFVILAKYRDSLLEDIREM
                     LTNAIISELDMNVTQTISYCIGAYLVEIDNLGYKSINSIMDKANIAHKVSKTRGISST
                     VWYNENLLKQLQMENSIYNYMYKAIENEEFHMYLQPKFQISSLNVVSAEALVRWFSPE
                     LGFLSPDEFIPLFEKSGFIIELDFYMLKKACSFVKKTFMKKNQYTYPIAVNFSRVTIY
                     QNSFYQRFLDTVKEYEIPFKYIEIEVTESAFNEISQPVISILEELKKLGFLISMDDFG
                     SGYSSLSLLCSLSINGLKLDKSLLKETFNREKVYSIIQCIIEMSHRIGMSVVCEGIET
                     KKDLEFLNTVKCDVGQGFYFSKPIEEKEFFNKYVTKK"
BASE COUNT        18491 a         8586 c         5998 g        20801 t
ORIGIN      
        1 taatttccag gaactataat tcttatcttt ttgaatacaa ggatataata atatacatct
       61 ttttgcattt tcatatgctg ttatatatgc atacatctgg tatatatcac ttgacctata
      121 aaaaacattt gaatctactt caatagcttt ccatttagtg tcaattataa tttcatattc
      181 attttttaag tcatataaaa ctatatccgg tcttaaatta aagtttttct tacctgtttg
      241 ttcatttttc aaaagaaatt tactcttatc ttgtatatat gtttctctaa atgaattgtc
      301 ccatatactt ttgattaaaa ttcctatata ttcttcatat aaagtattta tttcaaataa
      361 tatagaaaat gcctcttgat tattttgact attatccata gacaaattta aaagtagaag
      421 tctagctagt aaataacaat ctttaaatct atcattgttt ttataaaatt tataatccaa
      481 cagttttttt ctatctatat aaattaaatc tacattttga aaatagctta aaattttttt
      541 aatcttgcct tgaattgaat tgtcatttat tctacataaa atagatatac atgctttttt
      601 aagaacttga ttcaagaaat tattttcact atactcatca tattcacatc ttattttcat
      661 tggagaaatg cctttttctt ttgcatatgt acttaataat attttacccc tcataacatt
      721 taagttctct attttattta tatattcaaa ataaatacct tttttcatct gtgtttgcat
      781 actctcaatg aaatacataa caaaaaaatt taagagatta taatttttca aactcaatct
      841 tattttttca ttcattgtaa ttggaatttt attacatata gaaagcatct gtaatagtat
      901 ctctctatct tttacaagat tatcacttaa tgacaattta ggaagtattt caagtattac
      961 attttcaaaa catatgatgc ctacatagtt tataaatcta agttttttat atttaatatc
     1021 tattatatta ctttttaata catcattatt gttctctaga tatttaagca atttttcata
     1081 ttcaatttct gtaagctcat tttcaccatt acctaccctt atccattcat aggtttcctt
     1141 aacatatata tttttactca tatatatttt ttagctcctc actagatatg ttttgtttta
     1201 tacaatagtt aactttgctc tccattattg aggcattatt atttttaaat aactcagaag
     1261 ctataagttt ttctttataa acaatatatt tatctttttc atttcttcca attcctccta
     1321 aaatcaaacc tactttttct gaatcataat aaaaatactc ttgaagaagt ggtattattt
     1381 tacttctaaa tactactact atatcattaa tattttctac agcaagtaga taagcttgtc
     1441 caataacatg gtctctatca tataaaaact ctatcctttt attgattgta tatagcattt
     1501 ttctaatatc tataccatct acaatagaca ataaatcata atctggcata atttcttcaa
     1561 aattaaacct tcttcttaaa gctatatcta aaagtgctat tgatttatct gatgtgttca
     1621 tagttccaac tatatacaaa tttggaggta gagaaaattt ttcctttgaa tatggtagtt
     1681 tgacaatagt ttgatttgat ttagtaagtc ttttatcatc ttccaataat gttattagct
     1741 caccaaatat tttagataca ttccctctat taatttcatc tattattaaa acatagtttt
     1801 ctgattcttc aaaattaaaa ctctcactat attctatatt ttctaatact aatttctttt
     1861 tcctgtcttt tatagtttct aaagtcaagc tatctttttc caactcaaag ctcatctttt
     1921 tttcaaattt caatgcatta taacatgctt ctatagatat atcctttaat atcccatctt
     1981 ctggcttaaa attgccttca ccatcagact taagaccctc tataaattcc tcatatccat
     2041 atgattgatg aaatgtacaa aattctacat tgtttttata atctaagtaa cctgtatagt
     2101 atttgtttct tagactggtt tcacttacta gattgtaaac catctgtttt gtattgtatg
     2161 ttttaccagt tcctggtggt ccataaagta tagtatttaa tggcatttta ttagtaaatc
     2221 tttttacata cttttcaact atactattat tttcaaatat aacccatgca tttccgtcta
     2281 tattctcctt ttcatactct atccatctaa caggaaaaaa atatccacca tccaaagcac
     2341 ttactttctc tttatcgaac ccttccataa cttgatatac gccaaataga ctcttcattg
     2401 tatggtcatt ttcacaaatt actttctcgc tattatacaa taaaatataa tcatctgtct
     2461 ttatattttt taggctttct aattgttcta gattaatggg ctgaataaat aattcttcat
     2521 catctacaca cttatctaca tttttataat aatagttttt taaataccat ttattatttt
     2581 cactttcttc tattcttttt ctcaataatt tcttatcttg tgacttaata atttctaaat
     2641 atgaactaat atcattatta tttaatttat aaaattcact tgtatatact ttacaatttg
     2701 aaactgtatc aaaattatgc atccatttta ctggtagtgt atgccctaaa atatgactta
     2761 attcatatcc attttcaaaa tcttcttcaa ctatgccaat agacacatta catttaactt
     2821 tttcttctat attttgatat gctttatata aaaaataatc tcctttttta atcgacataa
     2881 acttttttat aaaatcttta tcattacaat tctcattaat atacttttct gattttttcc
     2941 ccatactgaa tacttttttt aaatttattt ttatatcaaa tccaagtgca attatgcttt
     3001 cttctctaaa aatctgtggt gtgtctgttt cctgataaaa aaattcttcc attaaccaat
     3061 actctgtacc tcttatattt tcagacatat acactctcct taatatctaa aatatactaa
     3121 ttatacaata agcctactct aatatttcca tttaaatttt cctttatata taaagaaaat
     3181 attacttcat agctttcttc taccttgctc tgaatattac ttattaaatc attcaattcc
     3241 attatagaaa attctggact tccttcaaca aatacaattc ctttcttact tataaattcc
     3301 tcaccaatat attccatcct gtcaaataaa atgtcagcta tctcgctata tgactttgta
     3361 tcttcaaact ctccaaaaga atacttaatt cctttatctc ctacaatagc ttcttttaaa
     3421 tcagtaatat ctatatttat catgcaagaa tcagaaatag actctaccat gatattcatt
     3481 aaatcaacaa atttaaatat actatcatta ttgattttaa actctctccc aagctctaaa
     3541 tcttctttat tttctttctc tgaacaatcc attcctatag atagaactct tctttcattt
     3601 gacatatatg aaacagcttt tataatatct ctaatatgtt tatcttcaga tgaatatatc
     3661 aaaaataata tatctacacc atctaaaaga cttctaacat attctttttc aatctcttga
     3721 tttatgttta ttttttctat atccatattt gcttttattt tttcttctac ttcatttatt
     3781 atattaatac cttcagctcc aataccaatt attttagcat tcttattaaa attttccatt
     3841 ataacgtata tctccttaat aattatttaa tttcaacatt tctaaatatt ataccatatt
     3901 ttcttcataa aaatatctta actcattggc cttatcataa agtagcttat tcaaaaattt
     3961 tggctctata accttagcat tatttccaat aaaaaataaa atcgaagcat aacaatctat
     4021 atcttcaacc tttatgaatg tactaattat tccactacca tcttcattta gctccatatc
     4081 taaattccaa gaactgtcct ttattttaga aacaccttct ttagttaata atacatttag
     4141 ataaataatt tcaccaaatt ttttagtagt tgaactattt ccatataaat tgttatatac
     4201 ttcatgtaac cattcttcca agtttatatg tattttttta ctttctcctg ttctttttat
     4261 atcaattata ttatctatat gaactaatat tattttatca cttttacaat catatgctgg
     4321 tgaaaaccat gctcccttat ttaaatatat acctataggg catacgtttt tttccaaaat
     4381 ctgattacca cacttatact taatatttaa aattagagat tctgaagaag ctctaaaaaa
     4441 ctcagttaca ttactactct taaaatctcc atcattagta tcattagcta caaagccaat
     4501 gtatctttta atattttcta tacctacttt tatactgctt ttacgttcat aacttacttt
     4561 tctcattata gaattaattt ctatttccat taacttataa ttataaatct gaagtgactt
     4621 aagtgcaaat agtataatca taacttcttt ttctgtaaat ataacaggag gtatatagct
     4681 attatttagc accctataac ctccatttct accttgttct gcttgaattg gaagtcccat
     4741 tttatttaat tcttttaaat atcgttgtat tgttttagct gaaagattaa attcctctga
     4801 caactctttt attgtaaact tttgcttatc attaatatat atccaaacat cagtcaatct
     4861 ttttaccttc gacaaataaa cacctctttt cactaataat actctcaatt aattaaatta
     4921 ctatacacta tttaaaattt aatattaatg acatttttat attttttcat taaaaagcag
     4981 aaaaatggta ctcctacaat tgttactact acaaattctc caaaacctac ctgtatcata
     5041 gatagaatta atggaagccc aaagaataca tttaacatta gaccaaccac aatcgaattt
     5101 ataacagttg gccataaaga agctataact aaagtacttt tattttgttt acctaacttt
     5161 ctagtaatat aaatcatact tgcacttata aatgtggcta atgttccaaa aattatatca
     5221 ggtacaccat atggtcctat tacatttgct aaaaaacaac ctaatgtaag acctactata
     5281 tatcctttat ctaaaaatgc caaaagcatc ataatctctg ctaccctaaa ttgtattggt
     5341 ccataactta taaatcccaa tgataatgtt aaaactgcat agattgctgt aattgctgca
     5401 gttagtgcta tattaatact attttttctc atatctgtct cctagtaaaa gttttatttc
     5461 taaaaaaatt aataacataa ctttatttta tacaaaatct ataaacttaa acagtaattt
     5521 tataaaaaca aattatttta tcgaactatt tttccaattc attttacatt atacaatata
     5581 atacatacaa attcaatttt atatatatag aatatatgat attaaaatta tatacaaact
     5641 aaagataagt tttctattgt taattaaaaa cagcaaaaaa gagccttaaa attaggctct
     5701 aataatttat tttaaaatca gtgaactcta ctaccatctt ttaatttaga taatatcatc
     5761 caagtaccta tacaatcaat ttccagttgt ttctctattt catcatataa catttcttga
     5821 tatgatgtat ttaaaacaac attttcaacc aatttagaaa tttcctcttc tgcaaaatca
     5881 atttctattt gattttgttt ttctttaaaa aataccctta cttttctctg acttattgaa
     5941 cgaccctcaa agctgactaa acattctaaa atgttcttat ctcctctaaa attatttact
     6001 gctctcatat tatttagatt accagccaaa acatcatccc cttatttaat tttgtatttt
     6061 ataagtaaaa ttcataatat tataataact acttattaaa tatctttcaa caggtatgac
     6121 ataactggtt gtttaacatg taaaactagt ctaaattttc ataaataatt atttattcat
     6181 ttccataaaa actttttcag gtgtaatagg gagtgtattt attcttacac caattccatt
     6241 aaacacagct tcttgtattg ctggtaaagg tgtatttata acaacttctc caacagattt
     6301 agcaccaaat ggtccagttg gttcataagt ttcaacaaaa tctactttaa catttccaat
     6361 atcacatcta gctggaatct tgtattgcat aaatgtattt gtgtccatgc ttcctttttc
     6421 tgtgtatcta acttcttcaa ataatgccat tccaatccct tgaacaattc caccttcaac
     6481 ttgtatctta gctagatttt tatttataac cgttccacaa tctactacag ctacataatt
     6541 tactaaatca acttttccag tttctgtgtc aatttcagtt tctgcaaaac ctgctataaa
     6601 aggtggagga gatactgggc taccatgaga agcaagacct attaattgat tagtatctgg
     6661 accaattgta gaatcaactg ctatatcgaa taataaagtg ctaccttttt tactagttaa
     6721 ttttatacca tcaaattcta cttcatcctt ctcaacacct agtttagttg ctccagcaga
     6781 aattattttt tctcttaagt cttgagctgc cttaactact gccatacctg ttacataagt
     6841 agtacttgaa gcatatgaac ctgggtcata tggaactaag tcagtatcag ctgatataac
     6901 tgttatattt tcaatgcttg tatcaagaac ctcagcagcc atttgagcta aaatcgtatc
     6961 acttcctgta cccatatcag tagaacctat cataagagta taatctccac agtcattcaa
     7021 ttttatttca gctgaagact tatcaagacc ttgtatacca gaaccttgca tagtaattgc
     7081 catacccaca cttctaattt ttccattatc aagatgttta caaggatatt tttcattcca
     7141 tccaataagt tctttgcctt tatttataca ttttattaaa tcgacactat ttaaagtttt
     7201 accatatgca aatgtagttt caccttctgt taccacattt tttaacctta aatctgttgg
     7261 gtccattttt aatttattag caagcatatt tatagttgat tcaacagcaa aacatccttg
     7321 tgatgctcca taccctctaa gtgctcctgc tggcatctta ttagtatata ccacatctgc
     7381 aataaatctt gttgcttcaa ctttattata cattggtaaa gttttttctc caaccaaacc
     7441 aatagttgta gaagcatgct ctccatatgc tcctgtatca gaaagtgctt ttatatctat
     7501 tgcctttatt atgccatcat ttgtagcacc tagtctaact tttaatctca ttgcatgtct
     7561 acttgttgaa caattaaaag tttcttttct atcataaatt attttagctg gtttccctgt
     7621 ttttaaagta acaattgcag aaaaaatctc aacacacgca gtttgtttac caccaaatcc
     7681 gccaccaatt ctaggtttta taactctaat tttgctagct ggtatttcta gtgcacgaga
     7741 taaatgtctt tttacatgaa atggtatttg agttgaactt actacaacca atcttcccat
     7801 atggtctaaa taattgtatg ccctatacgt ctccatcatt gcatgtgctt gagcttgagt
     7861 ataataagtt tcttcaatca ctacatcaca attacttaat actttttcta catcaccttt
     7921 tgtataatca tgatgggata ctatattttt ttctctttgc atacctatat caaagttaca
     7981 atgtctatct tcatcatgta ccatagtttt atttcctatt gcctcttcaa aatccaaaac
     8041 aggtgtaagt acttcatact ttactttgat aagattcatt gctttaattg cagttttttc
     8101 atctatagct gccactatag ctacttcgtc acctacatat cttacaacat cttcaagaat
     8161 taatctatca tatggagatg gctctggata tgtttgacca gcaagtgtaa atcgagattt
     8221 tggtacatct ttatatgtta aaacacattc aacaccatca accatttctg cctttgatgt
     8281 atctatatct tttatttttg cataagcgtg aggacttcta agtatcttta ccaccaaagc
     8341 attttttgct gataaatcat ctgtatatac aggctttcct gttgtgatac tcattccatc
     8401 tattttcttg attccttttc caactatatt catgttctat tttacctcca gataagtttt
     8461 gatagctctt aactgtccca tataccctgt acatctacat agatttcctg taagataatg
     8521 ctttatttca tcatctgtag gattttcaag ctcatccttc attgcaagta cagtaagtat
     8581 aaagccagga gaacagaaac cacattgctc agctccttct tttaccaaaa cttcactaaa
     8641 ttctttaact tcattttcta aaccttcaat tgtagttatt tctttatcta aagctctcaa
     8701 tgtcagtgtt gcacaggata atgtaggttt cttgtcaatt aaaactgtac ataaaccaca
     8761 acagcctgtg tcacaacctc ttttcacact taaattacca acttttctta aagtatcaac
     8821 cagatattct tctggttcta tatcaacact ttttttcttc ccatttatat taatctttac
     8881 taacattaaa taacctccat tatagctctt tttaaaagta ctttactcat agcttttcta
     8941 tactccctag atgctctcat gttagaacca aaagttagtt cttctgatgc tatttctact
     9001 gctttatcta tattaatttc attgatttca ttgttagata gaaattcact agcttgtttt
     9061 gcaatcgtag ctttctgcgg tcttgctcct acacataact taaattgttc catatgtttt
     9121 gatacagata catttagaat tggataatca ctctttgcat ttctaagtga tttataagaa
     9181 gcattcttat ttgtcttctt tatgtatatc ttaataagta aatctttctc ataatctcta
     9241 tttagaaact cttcaagact aattctccca atattatata attctacttc cgtatctaat
     9301 gaaagtaatg ctactatcaa gtcagaaaaa ccatatttag aaaatactgt tgcaccaact
     9361 gttactacat ttctaaactg aactcctatt atatttttaa ctgaatcttc tattattctt
     9421 ccaaaattat tttttattat ggaacttgtt tctaatgttc taaaagtagt catagaacca
     9481 atctcaacgt aatcttcata ctcttttata taatctaaat ttaatttaga taattctatt
     9541 cctgttccta ttcttttttt ccccattctt aaaaaagcac ttccaccaat tacttggtta
     9601 gtttttcttt tatttaaaat tgagtacgct tcttctactg tatctggctg tacaatatcc
     9661 ataaccgtaa acataaattt cctcccttat ttgctattct tattttaaat acaactaatt
     9721 atatcatagc ttcaacaaat tttgataata aatatgtcta atatgtaaat tctgtaaatt
     9781 acttatacat aaaaaaatga ctatttcaat aatcatcatt agacaatatt aaaatagcca
     9841 ttaacaggta ctattttaaa gcaaaacttt aaaaagttga tactttttca cttatattta
     9901 tcactttttc ttctaataat ccaagttttt tagctactaa ttttgtagta cttccttgta
     9961 ttactaatgt aattagtata gtcataaata ctacagatga aatcacttcg tatccaggaa
    10021 ctttcattgc tgaaataata ccacaaagtg ctgctggtat tacgcctgtt tcccttaccc
    10081 acatcataaa taatatttca cttttactcc attttgcttc cctgtctaca agtgtacaaa
    10141 ctaaaacgca aagtggtctt gctataaaca ttaatactaa tactgtaatt acagatggca
    10201 taaaatattt acttaactga gccaaattaa cttggctacc caatattata aatattgcca
    10261 tacgacaaat agtacctaaa gtttcagcaa cataaaaatc tgcatcataa gatttttgac
    10321 ttaaccaaat tttaaagttt ttcttgttac cagttattat acctacaata aagcaagaca
    10381 tatatccact tccacctaat tttgtagata attcatatgc aactacaact gaaataacag
    10441 atattattgg tgcaaaatct ttaaatattc cataaggttt atcattaact aatttcaaaa
    10501 gcagtattcc tgtaattaaa ccaactaaaa ctccgacaat aaccattgtc cccagttcat
    10561 aaatattttc acctaatgaa aatttatttg acaaaattac agccaacact gctgatgtta
    10621 gtatagctcc tgttgcatca ttaaaagctg attcacttat tacagtttgt tttaccctat
    10681 cctttatctt tacctgatta aatataggta caagagtggc tgggtctgtt gatgctatta
    10741 tagttcctgc tagtaaagca gtcattgcac ttatcccaaa agtaaatcct attacttgtt
    10801 gcattataaa agcagatatc acaactccta aagtagctaa taagaataca gatatcttca
    10861 catttctcaa tacttttaaa cttatttctt ttccacctaa atataaaata aatgcagaac
    10921 caaatgtaag tattagttga ttttctattt gaaatccacg aatatctata aattttaaaa
    10981 atgatggtcc tattaaaata cctacaagta aatataacac tacatctgga acctttatta
    11041 tttcactaag cttactacaa attattccag ttatacttac aatagcaaaa attatcaata
    11101 aattattgct ggcaattgtg tgtatagatg cttccatgtc cgtctctcct cccgatttgc
    11161 atacattatg caatatactt attgttttac tatataatta tagcacacaa ataaatgtta
    11221 tcaatcattt tttttaggac atgcaattta gctttcattt ttgataatta aataacgctt
    11281 atataatttt gctatttttt gctagttatt aaaaggttga ttttgtcaag tttatagtat
    11341 atatatatta atatttttta tatccatatc tttttagata tttttcgact ttttcctcca
    11401 ttaaaataag tttaaattta acaataaaac atttcattat atatattttt taaaatgtac
    11461 tattttcaac attttcatta acttggtcta ttcatttttt tcttatctat tctatatcca
    11521 agcatattcc ctatattttt acttacatgt aattcttgag ctatttcaag tttattatca
    11581 ttgctttgtt ttatcttaga aatctcactt tgtttttcat tttgtttatc ttgtttcata
    11641 gtttctcctt tcaaaacaat atcacttttt ctgtttatta cttattattt caaatttcta
    11701 taattttaat caaaaaaggg aaatatctca atataatata gcttactcaa caccatattt
    11761 atatatagaa tttccctaat tattttatta atttaatttt tcaataacct tatctaaatt
    11821 agaatttact ttatcttcct ttttccaaga atttaatgta taatgcgttc caaatgtaaa
    11881 taaacctgaa actattaata taaaatagta tacaaaccca ctatataaga gtacagagta
    11941 ccccaataat tcttttggaa ttatattgga gaacatagta aaaaatgtaa cctcattagc
    12001 tccaacattt cctggtgttg gaattggtga tatagccata tataaaaaga cctgtaatgt
    12061 cattatatgt acatatgaaa ctcctcttaa atttgaggct ttatacacac aataaactat
    12121 actgaaatat gcgattaatt gtaacacagt aagtaatata cttaaaacta agattcttac
    12181 atttttaata aatattttta tagaataatt ataatcatca atataatgat ttattctatc
    12241 acgttttgaa tctaaaaatt taaatgtttt aaatttagat aaaaaattaa tcaaaacttc
    12301 tgctatcatt tttacttgtt ttggactaaa tactattagt aatccaccta acaacatact
    12361 tacattcata atcattccaa aagttatcaa tactttcaca gagtgtactt gctccatcag
    12421 taatgactta tttagcaaaa ttaaaattcc acaaaatacg gtaacagtac tttgaaatac
    12481 tacagtttta ttagtaacta tagccactga tttactaagg cttacatcat attttgtaag
    12541 tgcatatatt tgcattggtt gactcccaga tgcaaatgga gtaactaagt tatagtaaaa
    12601 tcccattgta gccattttaa taccaataaa tttcactttt gttttttgaa ctgcatttat
    12661 tatcaaatga gttacaatag attcaattat catatatact ataattgtca atatgccaag
    12721 aaatatataa gtcttattta ctagccttat aattttaggt attagtttta tatctaaagt
    12781 agttaatact aaataagtag taatacatat caaaaataat aaaaatccat attgaataaa
    12841 atctttttct cttttggata attttctcat ttattttctc ctaaattttt tcatatcact
    12901 atacatagta tactacttaa cctattattt gcaagactaa aaaagataag tctttatttg
    12961 acataaatac acctataaat ttttaaatat tcttactcct ttagtagaaa taattctcca
    13021 tatcataaaa tctaatatca aagtaagtat acttgccaaa ataatatata tatttaaaaa
    13081 cgaaattcca agtaatacat atatacctcc aagtataatt acgtaagcta atgatactaa
    13141 cattgtaatt atcatacttg cacttctttt tactacagcc atctcatttt tccaatcaag
    13201 gtttggatat aataaatttg ataataatcc catcaatgcc acaaacattg aaaaacttgc
    13261 aatcaaacag attgatacaa taataaactg aatttcaaaa cctaatctta tagatactaa
    13321 tattaaacat aaaatagata atggtgcatt caataaaaaa ttcatcaata tttttgacca
    13381 gaatatttct ctttcatcta ttggagaaga tttcagtatc cataaatttt ttccttcaag
    13441 agaaattgaa cagtatgttg tacaattcat tactattata aagaagaata ctcccaataa
    13501 ttgtattttt ataaaattaa aatctatgtt caatttcagt aactcaccca ctttatctgc
    13561 tccaaataat aatattaaaa ttgtacctat tattaggaat aacaaacctg cagatgaatt
    13621 taaaaagtat ataaatgaag aagtatatct cttaaattct ttttttaata gagcttttga
    13681 aggtcttgaa gttttttggc tcttaaattt ataagttttt gacttatatc cttcactcat
    13741 cttagcattt atatctttaa atttttttgc aaataatgtt acaaacataa aaaatggtat
    13801 tattgaaatt gctataaatg ctaaaaagga aactacactt cctgttttaa gagcgtcaac
    13861 aaaataatat ataggtggat atatttttct aatcgtctct gaaatagata cactattctt
    13921 taacatctca accgacatag agttaagtct tgtcataagt agagtataaa gcaacatcaa
    13981 tataatacta cctataatta atattaaatt tttgtatttt attcttgatg atatctgtcc
    14041 tataaacata aaaattattg atgaagcaac tattggtaat aatggtaaag ctaaaaatag
    14101 cagtatcaaa taagggaaat acgttatact tacatcagaa ttaaaaaaat aaaccactgc
    14161 tggtataatc atacatattg aagaaaataa atagtttgct ccaaccaaca ttaatatctt
    14221 acttgctagt acagtagatt cttttatagg taaactagtc aaaaggtcta aatcttttgc
    14281 ttgaaacaga tatgatgacg ttttatataa tgatgtaaca atagttgtta atgttgataa
    14341 tccaaatcca aatataagta gcatttccat ctgatttatt tgctttaaaa tatcaactaa
    14401 agaaagactt atactagtta cataaaaaat caataaccct gttataataa caactgaaag
    14461 tatcatcccc attatttttt gtttttctct actatcagct ttttttaacg catttaattt
    14521 aaattcattt attatattag tttttattaa tatacttaga ttgctcatat tttatcattc
    14581 ctcactttag acactatatt gtataaaaaa cattttattt ctctattaat tccataaaga
    14641 tactttcaag tgaattactt cccttaactt cttctgtagt tccataagca attatatttc
    14701 catcttttat tatggcaatc ttatcacaaa ttttttcagc aacttctaaa acgtgtgttg
    14761 agaaaaatat acaaccacct ttgtcacaaa actccctcat aatttccttc aatataaagg
    14821 aagcttttgg gtcaagacct acaaaaggtt catcaagaat taagattttt gggctgtgta
    14881 tcaaagccga aattatagct aatttttgtt tcataccatg cgaatatgaa gatattaaat
    14941 ctcctaatgc tttattgagt tcaaacttat ttgaataata ttttattaac tcttctcttt
    15001 tgtctttggc aacttcaaat atgtcagcta taaaattaag gtattgtata cccgttaatg
    15061 actcgtataa atctggatta tcaggtatat atgccatttc ctttttacat tcaacaggct
    15121 gtttttttat agatttagaa tttattagta cttctccctc ttcaaaatcg tgtattccaa
    15181 caattgcttt aatagtagta gttttacctg ctccattatg tcctataaac ccaaaaagct
    15241 ctccatcatt tacatcaaat gagacactac ttactacttt tttattttta tatgatttag
    15301 atacattgat tacttttaac ataatttccc tccatattat agttttgata tttgttatat
    15361 ataatatata acaaatatca aacaattaca acttttattt gtttatttta gaaatctata
    15421 aaatgcaaag gtatcagaaa tataaaggta taaatataat tgatatttac tttcaaatta
    15481 cacataatta taaaagaata tatagttcga tttgaataaa caatgtataa taaaaaatag
    15541 ttgactataa ttattaaata taaggagcaa aatatgaata catttgaaca attaaaaata
    15601 agttccactc taatagatgg acttaaaaaa caagacataa cttctccaac agaagttcag
    15661 tcacttgtta tagggaatat aattcaaaat aaggatttat tgattaattc acagactgga
    15721 acaggaaaaa cactagcgta ccttttacct atatttgaaa aaattgatac atcaaaaaga
    15781 gaaacacaag ctcttatact tgcacctacg catgaattag taatgcagat tacaaaccag
    15841 gttgaattat tggctaaaaa tgcagaactc tccgttactt ctttagcttt gattggggag
    15901 gtcaatatac aaaaacaaat aaaaaatata aaagcagtaa aaccacacat agtaattggc
    15961 tcttgtggaa gagttttaga cttgataaaa caaaagaagc taaaatcaca taatataaaa
    16021 actatagtct tagatgaagt ggacaatcta ttgaatggaa aaaatataac ttgtatagaa
    16081 gacataataa gaacaacgtt aagagataga caaattatag gatgctctgc aagtcttact
    16141 gatagcacta taaaaatttg tgataaactt atgaaggagt ttgaaataat aaaaacaaag
    16201 gaaaaatcac aaataaatcc taacatcaat cactcatatt tattaggtga gataagggat
    16261 aaatttactt ttcttagaaa ggcattagca gctacaaatc caaaaaaagc tattgtattt
    16321 gtaaataatg aaaaaaatat agaagtccta gtatcaaaac taaattatca taattacaaa
    16381 gcaataggaa tttttggaaa tatggaaaaa gaagatagaa agaatgcaat aaataaattt
    16441 aaacttggta aagcaaagat tttaattaca actgatttat ctgctcgtgg actagatatt
    16501 gtggatgtaa gtcatgtttt taacttggat tttccaaaaa gtaaaaatga atacctgcat
    16561 agatgtggtc gaactgctag aggaaatcga agtggtaaca caatctcaat aataacaaaa
    16621 aaagaattag atattataaa agatttgcaa aaagagttca gtatagtaat tacacctaaa
    16681 actttacaaa atggagaact aatagacatt attaaataat acaataaata cgaaaataca
    16741 acaaatacaa aagagctgta gtttatcatc acaattgata ataaattata gccctttatt
    16801 ttatattaaa ttaaaatttt aaataatacc tattataata gccaaagttt tattataaat
    16861 aatattgcca gaacaatcat tactacagaa acatgttttt tgtcttctgc ctttttagct
    16921 ccaaatatat tataaaatat atttacgaaa acataagtta atatacctaa agttaaacca
    16981 tcacctatac tatatgttaa tgccatacaa gcaatagtaa caaaagctgg aacaccttca
    17041 gttatattat caaactctat atccttaact gtaccaagca ttaaatatcc aacatatatt
    17101 aaagctggtg ctgtagcaca tgatggaatt gctataaata caggagagaa aaacattgca
    17161 gctaagaata aaattccaac tgttattgct gtccatccag ttcttccacc tgcgataact
    17221 cctgttgaac tctcaacata agttgtaact gtagatactc caagtcctgc accaactgta
    17281 gttgcaaccg catctgtaag taaggctcta cctacattag gaacattccc tttttcatct
    17341 aacatgtttg ctttagaaca aacaccaact aatgtaccta ctgtatcaaa aaaatcaaca
    17401 aataaaaatg tacaaactac tactaaaaaa ccacctatat ttgttggatg tagtacatat
    17461 cctaaatcta ttttacctgc tattggtgct aaactttcga atttaaataa tccaccaggt
    17521 aaatatatac ctaatttttg tgcatactct ggattcataa aagcaaatgc ccaagcaagt
    17581 aatgaactca ctactattcc aaaaagtata gaacctttaa ctcttttttt atctaataca
    17641 gcaataatta ttaatcctac acaagttatt attactgctg gtgtaaatct acccattttg
    17701 ataagagtgg cttggtctcc aataacaatt ccactgttaa ctagacctat aagtgcaata
    17761 aatattccta taccacctgt aacagctaat ttcatatttt ttggtatcgc atttacaaca
    17821 gcctcacgaa ctccacttac tgataatact ataaaaataa taccttctac aaatactgct
    17881 gtaagagcta cttcccaagg aacacccatt tgtaaaacta ctgtatatgc aaaaaatgca
    17941 ttaagaccca tacctgatgc taaagcaaaa ggaaggttag caactacacc cattaaaata
    18001 catccaaatg ctgctgctaa acaagtacct gtaacaagtg cacctgcagg catgcctgtc
    18061 tcagataaaa tatttggatt tacagctatt atataagcca tagttaaaaa agtagttact
    18121 cctgcaatta tttccttctt catgtcgaca tttttattag tcaaaattgg aaaaagtttc
    18181 tgcatagtac tactgtttgt tgtttgcata acaacacctc ctattaaatt ttacaaaaaa
    18241 acgacacagt agttgataag ctgagccgta tccttcataa ttcagttaat taaatattta
    18301 attaactaaa taatagtata catagtcaga atatttacgg tattccggta gaaacttatg
    18361 acccatattg tcaaaattat atgttataca gtacaaaaca tgaatttttc tttacgaata
    18421 ttattttaat ttatataatt aattttgtca atatatacgt atatattgta ttgattttgt
    18481 attaatattc gattatatta aatattgatt tattaaattc aaattataat tatattcttt
    18541 acattttaaa aaaatatatg atattttgat acaatttatt tatagtttgg atataaagtt
    18601 tatgttaaga ttatactata ataaattaat aattttttta tttggaggaa taaggtgaaa
    18661 gatttaacta caggtcatga gggaaaatcc atattctttt ttgccatgcc tatgcttatt
    18721 ggtagtttat ttcaacaact atacaataca gctgacagta taatagttgg tagatttatc
    18781 ggaaaagaag caatggcggc agtctctgga gctaacccta taatgttttt attggtggca
    18841 gcgcttatgg gtgttagcct tggattttct attttagtgt cacaatttta tggctcagga
    18901 gatttaaaaa aggtaaaagc tactattgat actacatata tacttttatt tattggttct
    18961 atattaataa gtattcttgg aatagtattt ggtggcccaa tgcttaagct tatgaataca
    19021 ccagaatccg tttttgctca atcaaaattg tatcttacta taatatttag tggaatatta
    19081 ttttctgctg gatataattc agtaagtgca atacttagag gacttggaga ttcagtaact
    19141 ccactttatt ttctgataat agccacaatt ctaaatatag ttttagactt aacttttatt
    19201 gtagtgctaa gaatgggtgt tgagggcgtt gcacttgcca ctataatggc tcaggcagta
    19261 tcatttataa taagtataat ttatttaaat aaaaaacatg aagtgcttaa atttaaaatc
    19321 aaaggaattg tatacgataa caaaatattt aaagatggac ttagattagg acttccaagt
    19381 ggagttcaac aaatgttgtt ttcaattgga aatatgactc ttcaattttt agttaatagt
    19441 tatggtacat ctgctatggc agcttttggt gctggtctta ggatagaaaa ttttataagc
    19501 ttacctatta tgaatcttgg ttctgctgtt tctacttttg ttgctcaaaa cataggtgct
    19561 ggagaaaatg aaagggttaa aaaaggcatt cgagaatcta taaaaatgac cttagtttta
    19621 gcagttacag ttattacttt aattttgcta tttagggaaa atctaattgc tctattcaat
    19681 actgataaag atgtcattaa aattggctct tcttacttat ttataatagg accattcttt
    19741 ttatttattg gaacttcttt tgtactttca agtgcaatga aaggtgccgg tgattccatg
    19801 tttgcactta taagctcaat agtatcttta tggcttggaa gacttccagc ttcttatatg
    19861 ctttctaaat tttttggaac agacggaatt tggatgggta ttccttttgg ttggacttta
    19921 ggtcttattg ttacagttat ctactataag aaagggtatt ggaaaactaa agctattgta
    19981 aatcatagaa tcaatgaata atctttttat aaaatgtatt cacattcatt gtattcacct
    20041 ccattatgat ataataaatt atggaggtga atataaaaat gggtattatt cttaagccaa
    20101 aacaatttta tatgactgtt atagctacca taattctcta cttctctctt aattacagtt
    20161 tcaacataaa attttctata tgcttatctt ttttaactat cttgatatgg gctgtagact
    20221 cagttgaaaa aacttttgtt gcattgtttt ttgtaattct agcgtttata tttaacattg
    20281 caccaataaa ggttatttta cagtttttat ttacagaaaa tttttacata ataattcttg
    20341 catacataat tactaatgca gttacaaaaa caggtgtcgc aaaaattatt tctgagaagt
    20401 taattttaaa tactgtaaat acccctaaaa agatgattct tttatcgtat attttaggta
    20461 ttcttttaat attttttatc ccacaaccat ttccaagggt tattcttgta tctgcttttt
    20521 acaaggagtt tttaaaagaa caacagataa ctgaagattc aaaatctata cttttattta
    20581 gtatatttac agcatctacc tttacatcaa tgttttttgt aaatggagac acccttctaa
    20641 actatgttgt actagaactt ggaaattgta atataaattg gggtcaatgg gctttttata
    20701 tgtctgttcc aactataatt acttgtttta taacttattt tttatttatc tttgtcttta
    20761 aaaaagaatt gcattcaata aaatttattt ctcatgaaaa tcttgagggt aataaacttc
    20821 atttttcata ttctaattta aaaaaagaat ttaatttgct aaacaaagag caaaaacacg
    20881 tatttttatg cctaggaata atgtttttta tgtttttaac tcagttcata cataacataa
    20941 acacattaat tataatgtca atttgtgtac ttcttttatt actaagaaaa atagttggat
    21001 ttagtacttt aaaagaaata aattggaagg tccttatttt ttttatagca gcattttcaa
    21061 ttggaggagt gttaaagtac tctggagttg tagatataat gggaaattat ttgataaagt
    21121 ttataccaaa ctcttcagaa attatttcga tattattttt gataactctc acaataatct
    21181 tgaatatatg tcttggaagt gctgtcacta catcatctgt agtaataccg ttacttggaa
    21241 gtttacatat actaaaggaa aatagtgtta ctttatgtct atttgtctac attatagtaa
    21301 gcatacagta catattacca tttcatcatg ctacaataat ggttggtcat ggtgaaaatc
    21361 tgtataatag caaggttatt ttcaaatacg gtttaacttt gattccttta acctacttta
    21421 taataatatg tataacatta ccttggtgga aatttatagg actagaaatc taaaaaagat
    21481 gaaaatatga attgacttaa gataataacg aaattattaa aaagaaaatt catattttca
    21541 tctttttata taagttcttg tgaaattgga caaaactact cttttaccat aatactaaat
    21601 attatttgtt ttacttcctt ttccaaaagt attctcccaa tcctctataa acttatctac
    21661 actccaatca gttaatggat gattcatcat agatttacaa atatcatatg gtactgtaac
    21721 actatgcacc ccatgttgca ttaattctat aacttgttgt gcatttttaa aactggctgc
    21781 aagtactttt gtatccattt tataagtatc tattattttt ataagttctg aaaccatagc
    21841 tactccatca ccagatatat tatcaagcct atttacataa ggtgcaatat aatttgctcc
    21901 agcctttgca gctaaaaaac cttgatgagc agtgaatatt gcagtagcag ttatttttac
    21961 accttttctg tgaaggtctt ttatagctct taaaccatct tgtgttacag gtatttttac
    22021 atatatattt tttctcaaac tacttatata taatgcttct tctaatattt cttcatactt
    22081 tgtacttaac acttgagcat gtataggcat atcctcacct ataatctcac caatttcatt
    22141 tataagttgc ttaaaattct ttttttcttt tgaaacaata cttggatttg tagttacacc
    22201 atctattggt aaacaagtac ataactcctt aatctcctcc acattacctg tatctaagat
    22261 tagttgcatt aaaatatccc cctttaatct ttctttattc ttattatata ttgatttggt
    22321 attattttca acattttgct tattgttttt tattttttat tattgttttg cttttccttc
    22381 ttagttttat aattttttta tttactaaat tctaaatata tagttagaaa aaacatactt
    22441 tttatattaa attaattttg tatttcatgt taaaatagtt gatatattgt attttatctt
    22501 ataatattta ctataatact atattgcgaa aagaggtaga aaatgtttgc agaagaaaga
    22561 atccaagcta tattaaatat cctaaaaaaa gaaggtagag ttactgtcaa agagctcagt
    22621 tctaaattta atgttacaga agattgtata agaaaagatt taaaaaatat agaaaagatt
    22681 tcttcaataa gaagaattta tgggggagct gtactagcta gagaaacact agagaatcag
    22741 gatacaaaag acagaaaaga aattaatatt ccaacaaaga aaataatagc agaaaaagca
    22801 tttaatttaa ttgaagatag agaaactata tttttagata tctctacaat taacatcttg
    22861 cttgcaaagt tgttagctga aagtaataaa aaagtaacac ttgttacaaa tatgttggat
    22921 atactaaatg tagttacttc aaaaccaaat aatttaaata taatttccac tggaggttta
    22981 ttaaatctca gtttagacgg ttttgtcggt actccaacta tagagtttat atcgaaatat
    23041 aagtttgata agacttttat gggaagttgt ggagtagatg tattcaactc ttcacttaca
    23101 acttttgaaa ttgaagatgg tctcacgaag aaggctataa taaattcaag taaaaaagta
    23161 tttatagtta tggaagataa aaagtttaaa tttgatggaa atttcaagtt tgctcattta
    23221 gaagatatta gttctataat tacagaaaaa gcgcctactc ctgatatagt agatatttta
    23281 tcagaattta atgtaaatgt tttataagtt taattatata ttttatagga tttcttataa
    23341 atataaattt ttatttgata actattctta aaaacatatt tctataatat ttattttatc
    23401 cttagtatct attttttaaa atctagttct ataacatcta ctttatcctt atgtctattt
    23461 ataaaactaa tttgaaatag actttctaaa tctaatacag ttatttttag aaagtctatt
    23521 tccttaaata aactatttaa tattactggc tactttttat atgaatacaa taatttgtta
    23581 ttcataaata aaagcttatt tcatttcatt cttcatttgc ttctctaatt ctttagaaaa
    23641 tttcttttgt tcatatcttt ccatcatctc atcttttttc atttctaagt ttaccatagc
    23701 accttgtgca tcatctttca aatcttcagc tgtatttttc ataacataag ctgtcttttt
    23761 aacaccttct tttaaatctt ctttcatatt tttcatatct ctttttaatc tatccatcaa
    23821 aactacctcc tctgtaaata taatacttcc tatatttatt tttcccaaag tacatatatt
    23881 tatttgtaat atcaattata atttttaagt cttaaatata gtttaaactg tctaaatcta
    23941 tacatttcaa taaattaaat attttttatt tcaaaataaa aataacacta agcatagatt
    24001 atatgctcgg tgttattttt taaattcata gtaacttaat tgttgggtta ctataatgat
    24061 gacttatatg gaggatgtaa ggaaatctca tcattatagt tggtgtattt tatggtttta
    24121 agcttcttta tatttatata atacagtttc attatgaatt ttttgtgatt ttaaaatgaa
    24181 ctattattga aagttatata ttctttataa taagtaatta atttttaaat tctactgtga
    24241 atactacaga gttttctttg ttttttatgc tataatcaaa cccatgactt ttaaaaattt
    24301 ggctgactat ataaagtcca agtccacttc ctccagtttt tcttgaacga gatttttcta
    24361 ttctataaaa tggattaaat atttcttcta aataacgttt ctcgatagtt acaccagtat
    24421 tttcaatttc taaaaccact ctttgattag aagtcttttt acttattcgt ttatttttat
    24481 catagagtct aattataagc tctgattctt caggagaata ttttatggca ttatttatta
    24541 tattattgat tgccttagtt attctctctt ggtctgcctt aatttctaaa ttttcttcta
    24601 tttttaaaat agttttcata tgtttttctt ctattaaaaa tatttgtctc tttacaagtc
    24661 tatttaataa ttcacttata tttattgata ccaatttcaa atctttttca agtatttctg
    24721 attttgaaac ctctatcatt tcatttacta aatcttttaa ttcttgtgta cattcatatg
    24781 attttttcag ataagtatcc ctatccttat acttacctac actataaatc ataccttcaa
    24841 tttgaccact tattatggtt attggagttt ttagttcatg tgatattgta gcaacaaaat
    24901 ccttccttct atattcctgt tctctctcac tctctattat atttataaga ggctttgtta
    24961 ttacaattga atatatatat gctccaataa tcgctatcaa tattgctatt gatatgatgt
    25021 atggcattag ttttcttata acttcgtttg cttcgtcaat tggttgtaat ggcataacga
    25081 gttctaaagt atatggacca tcttttgcat ctttagtata tataggtata gaagttctat
    25141 actcatcctc aagactatta atcatgtact tactatatct taaaataact acttcattct
    25201 taccatatac aattttccct tggttatctt ttaataaaat agccaaattt tggtctttag
    25261 ccatataata aagtctttct tctaaagtat atgtatcgaa atgaattgaa ctatccacta
    25321 aagattttaa actttcttga agagactcaa ttttatactc atgataatat gatggcaata
    25381 aaaaatataa aattagatat attattaaag ctaacgctat taataatgat gtcgttattg
    25441 aaaataactt atactttata cttaactttt cccacttatc aaatatcctt ctcaagtgta
    25501 tatcctattc cttttacagt tttaatatat ggtaacgata ttttttttct tatatttttt
    25561 atatgtgcat caacaatcct agtatctcca taatagtcat aaccccatat actatccaaa
    25621 agaccttccc tagttataac ttgtggatac ttttctatca aagcttttaa tatattaaac
    25681 tcttttagtg taagttctat aggttctcca tctatctctg caatatatgt gtttaaatct
    25741 aattttaatt tttcaaaaac tataaatttg tcatttatag tcttgttact tcgccttaaa
    25801 attgcttcta ctctttttat aagaagatta aatgaaaatg gttttgttat ataatcatca
    25861 cattctaagt caaacccttt aagttggtct ccttcatcat ttaaagcagt taaaaatata
    25921 attggaacgc ttgatgactt tcttatcatt ttacaaactc cataaccatc taagtttggc
    25981 atcattatat ctaatattac taaatcataa cttccttgct taaacttttg tataccttcc
    26041 aacccatcat ttgctgtatc aacttgataa ccttctgcac ttaaaaattc tgatattaac
    26101 tcttgtatat ttgaatcatc ttcaattaca agtattgacg aattcattct atcaatcctt
    26161 tctattttat ttaaaatttc gtatattact tatattttat cttattgttg tgaattttac
    26221 atgaaaaaag agctatctta atttgtaaat taatcctttt aatttaaaga tagctctttt
    26281 ggatacattt tatttaattt attaatctaa tctctcttat atgccttgaa gtttttaagt
    26341 ctaagtgcat ttgatacgac tgaaactgaa cttaagctca ttgctgctgc tgcaatcatt
    26401 gggtttaata aaggtcctcc aaatacatat aatattcctg ctgctacagg tataccaatc
    26461 gtattatatc caaatgccca aaataggttt tgttttatat tttttatagt ttcatgacta
    26521 agtttaattg ctgttggaac atcaattaaa tcactcttca taagtactat atccgcagat
    26581 tcaatggcta catccgttcc acttcctatt gctatcccta tatctgcttt tgcaagagct
    26641 ggggcatcat ttattccatc ccctaccatt gcaacaaact ttccttgatt ttgtagtttt
    26701 tcaacttctt ttgacttatc ttctggtaaa acctctgcca aaaccatatc tatacctact
    26761 tgatttgcta tagcatttgc agttttcgca ttatctccag ttaccattgc aacttttatt
    26821 cccatatcat gaagtatttc tattgctttt ttactacttt ctttgactac gtctgcaact
    26881 gctattatac ctgataaatt tccatctaca gctatataca taggtgtttt accttggctt
    26941 gccaatatat ttgatttttc ttctaaatcc ccaagcttta tattattgtc attcataagc
    27001 tttctatttc caagtaatat actttcatca ttaatagtaa cttgtatacc agcacctggt
    27061 atggctttaa aattgtcaac tttttcaaat tttatattct tctcttctcc atacttaact
    27121 attgcttctc caagaggatg ctctgaacct ttttctgcac ttgaagcaat cttgataaga
    27181 tattcttctt ttacattatt atttaatact atatctgtta cttttggctt tccttctgtt
    27241 atagtacctg tcttatcaaa tatcactgta tttactttat gtgcagattc tagtgcctct
    27301 ccacctttta tcaagattcc attttctgcg ccctttccag tcccaaccat tatagcagtt
    27361 ggtgttgcta atcctaatgc acaaggacaa gcaattacaa gtactgatat aaatatagta
    27421 agtacaaata ctatatcttt tcctcctatt aaaaaccaca ataatgatgc aactacagct
    27481 attgcaatta ctattggtac aaaatatcca gatacagtat cggcaagttt agcaataggt
    27541 gcttttgtac cttgtgcatc ttcaactaac tttattattt gggcaagagc agtatctcca
    27601 ccaatttttt cagccttaaa cttaataaca ccatttttat taatactagc tcctgtcacc
    27661 ttacttccaa catttttttc tactggtata ctttcacctg taagcattga ttcatcaact
    27721 gatgtatatc cttctattac aactccatcc acaggtattt tagttcctgg ttttactaat
    27781 agtatatctc ctatctctac ttcttctata ggagtttcaa cttctttacc atcaactaac
    27841 actattgcag ttttaggttg tagccccata agctttttaa ttgcttctga tgtttttcct
    27901 tttgattttg attctaaata tttaccaagt aagataagtg ctattattat tcctgcactt
    27961 tcataataca actgatgatg gtgcatacct tgaatttgtc cattggctat ttgtagtgtc
    28021 gtatatagac tatataaaaa tgcggctaat gttcctattg caactaaaga atccatatta
    28081 gggcttaaag aaaaaagtga tttaaaccca tttatataaa atttataacc agctatcatt
    28141 actggtatta ctaaaattaa ctgaattaat gcataattaa aagtatttgt cataggattt
    28201 ataatttctg gcaaaggcca tggccctata ggctttatta tcataggtcc cattgctata
    28261 taaaacagag gtactgcaaa tactattgca actataaatt taacaaataa agacttcatt
    28321 tctctttctt ttctcaattt atcttcatcc acatcaacct tatttcttac ctcttctatt
    28381 ggtttatatc cagctttttc aatagctgct tttatttgag ataattttac ttttgatggg
    28441 tcatagtcta tattagcttt atctgttgca atattcacac taatactttc tactccatcc
    28501 aattttttta ccactctctc tacagctttt gcacaagctg cacatgtcat tccatcaatt
    28561 ttcatatcaa tttttttatt actttcttcc tttataattc catatcctgc tttttctaca
    28621 acctgcttta tatcatcaaa attaacctta gaattatcat attctatttt aagtttttca
    28681 gtagctatat ttacactttg gtcatatact ccatccatct tcttagttac tctttctact
    28741 gcctttgcac aagctgcaca tgtcatacct gtaattttat aactttctac cactttattt
    28801 gaactcataa taaaatcttc ctttctttca atatattttc agctaatttg taacgtttta
    28861 ttttgatatg taatattgat aaattactta tttagaaatc tatattttta ttataccccc
    28921 tataggtata ttaaatcaat atttttttaa taaataaatg tattagttat atttatttgt
    28981 atttaataga aaagtatact cataattaaa tgtatatata aaaatagagc atctaaattg
    29041 tttaatgctt atacaattta gatgctctat ttattataat ttatatttta tttaaaattt
    29101 attctttaca tgcttcaaaa aactctgctt ctgtttcctt tatttcaagc tcattgtcta
    29161 ttattccaac agcttctttt ttaaatgctc tacactgacc tatacaacca gtctttacat
    29221 tttcttctcc aaccaaagtt tttagcttat ttacatccac atttgaacag tttggacata
    29281 ctcttatcat atttaagttc ctcctaatta atgtctaatt aatactttta tacccaaata
    29341 taaactttat aaaagttttt ttaatataaa ttattaccat atataccatt tatatcctat
    29401 tgtgagtatt acatattaat tttatatatt attaatacta catgtacggt ggtatctgtt
    29461 gttttctcac tatttccaat tccttaattt ctaaagactt aatcacattt actttatagt
    29521 tttctttaga ctttatatac aaaacatctt ctatcttttt accttcaata aatttatgag
    29581 accacttaag aagttcttca aaattacaaa cttcttcttt tataaaagta tcactttcac
    29641 ttgcaaaata tttaattatt attttggtta cttccaacat atatcatcct ttactctttt
    29701 attaatcttt ttatctatta agattattat ttgtctaaaa aattttttta aacagaataa
    29761 ttttcagatg caaaactaac agttttatcc aatttaaact atattaatac aatttaatat
    29821 attcctcctt gtacctaata atatattgtg ctataattaa taagttattt taatcgaagg
    29881 gagcaacaaa aatgtcacaa aaacataaaa ttataaatat cgcagttata gcccacgttg
    29941 acgctggaaa atcaacattg gttgatgctt tcctttctca aagcggtgtt tttagaaaga
    30001 acgaagtagt taaagactgc gttatggaca gtaacgacct tgaaaaagaa agaggcataa
    30061 ctatatattc aaaaaactgt gcaataaact atgaagatta caaaataaac atagttgata
    30121 ctccaggaca cagtgacttt tcttctgaag ttgaacgtgt tatgaaaact gttgacacag
    30181 ttattctatt agttgatgct agtgaaggcc caatgcctca aactagattc gttttacaaa
    30241 aatctttaga gttcggttta aaaccaatat tatttataaa caagattgat aaaaaagacc
    30301 agagagcgga agaagtagtt aatgaagttt tcgatttatt tgtagactta aatgcaacag
    30361 atgagcaatg cgaatttcct ataatatatg gtattgctaa acaaggtatt gctaaacttg
    30421 aaatggatga tgatagtgaa gacctttctc ctctatttaa aactattgta aatcacgttg
    30481 aagcttatcc taattacgat aatgaacctc tacaattcca aatatcagct cttgcatatg
    30541 atgattatgt aggtagactt ggtataggta gaatttacaa aggtactctt aaaaacaata
    30601 cacaagttgc tatatgtaga gaagattctg ttgtatctaa aggaaaagta tcaaaacttt
    30661 ctgtgtatga aggtttaaaa caagttgaag ttgatgaagc tactagtgga gaaatagttg
    30721 ttatagctgg tattcctgat atatctatag gtgaaactat atgcgattta gatagtccac
    30781 tacctatgga aatgataaaa atagaagagc ctactctttc tatgaacttc ttagtaaacg
    30841 actctccatt cgttggaaaa agtggaaaat tcgttacaac tagacatttg aaagatagac
    30901 ttgaaaagga acttgaagta aatgttggtc ttaaagttga acctcttgat actactgatg
    30961 gatacaaagt ttctggacgt ggagagcttc acttatctat actacttgaa aatatgagac
    31021 gtgaaggtta tgaagttggt gtttctaaac ctgaagtttt aatgcataaa gaagatggaa
    31081 aactaatgga accaatagaa agagttgttg taaactgtcc tgaagtttac tctggtacta
    31141 ttataaatga attaaacatg agaaaaggta tgatggagtc tatgtcaata gaaggagact
    31201 atgtaaaaat agagttctta gcacctactc gtggtctttt aggatatcga agtgaattta
    31261 taaacgctac tcgtggagaa ggtactttag ttcgttcatt tgaaaaattt gaagaattta
    31321 aaggagaaat accttcaaga ggaaatggtg ttttaatagc acaaggacct ggtgttacta
    31381 tggggtattc tcttaatgcc ttaagtgata gagctgtaat gtttgtagac cctggtgtag
    31441 aagtttacga aggtatgata attggtatga attccagaaa agatgatatg gtagtcaacc
    31501 cttgtaaaaa caagaaaatg agtaacgtac gtgcttctgg ttcagatgat gctataaaat
    31561 tatctcctcc tagaatattt actcttgaag aagcactaga gtttatagaa gatgatgaat
    31621 tagttgaaat tacacctgat tctataagac ttagaaaaag attcttaaat gaacatgata
    31681 gattaagata taacaaatct agacaaggta aataaaacgt acatttacct ctaattaaca
    31741 aaatagccat atagtactga aaaattattt cagtttatat ggctattttt atttgaaatt
    31801 tatattattc aacatttata taattagctg cttgaacggc tgcaatagct ccatctgatg
    31861 ctgctgttat tatttgacgt aaaaacttag ttctactatc tcctgctaca tatacacctt
    31921 ctactgatgt tgtacaagac tcatctgaaa ttatatatcc accttcatcc aaatcaagaa
    31981 cattttcaaa cattttatta ttaggtttaa gacctatagc aataaaaata ccactaacat
    32041 ctatagttct tttttcttca gtctttaagt tttttacttc tattttcgat acagtctttt
    32101 ctccttctat tttttctaca ccatgactgt aaagtatctc aatattctct cttgctttca
    32161 cagatttctc caacacttct tcacctctaa aactatctct tctgtgaatt aaatacactt
    32221 ttgtacaatt attagctaaa aataaagcat cttctagtgc agtatttcct ccacctacta
    32281 tagcaacttc tttatcttta aaaaaggctc catcacatgt tgcacagtaa gatactcctc
    32341 tacctgtaaa ttcttgttcc cctgcacaac ctaatttacg tctttcaact ccatttgcaa
    32401 gaataacagc ctttgcttta tgttcacctg aagaagtttt tacaaccttt acttttccct
    32461 ctaaatttat ctcttcaacc tcatcaaact gaatatcaac accttgagca actgcttgat
    32521 tgtatatatt attagaaaat tctaccccag aaatcttttg aactgctgga taattttcta
    32581 cctcagaggt acttgcaact tgacctccat aaatattttt ttcaaatact gtaacgctta
    32641 accctgctct catagcataa attgctgaag ttaaacctgc tggtccagca ccaattacaa
    32701 tgatatctac cataatgttt acctctcttt atattattat ttcttatata ttattctcat
    32761 cattcttata ctttactatt attatccata tatactacaa acaaaacatt attttttatt
    32821 aattaacttt attttacata tatataaaaa aactgcaaat aaaaattaac ttttatttac
    32881 agttctcact tatttatata attcaaaacc ttattggtta tcatttacag tgtcttctaa
    32941 tatattgctt tctgatatat atgatagaat tgaaagtcca tacataacca aaactaatgc
    33001 tgctgttata agtactattc ccatatttaa tacctccttt tgtttacagt atactattat
    33061 tatgtgaaat atttatgaat ttaatttgaa tatatatgta atttcacact aacaatttct
    33121 tcaaattaaa cattattaac tatatacttt cgttgaacca attatgatta atagtttaaa
    33181 tattagcact atttacttat atttatatga tataccatat aattacattt ttcaaattaa
    33241 agttttgtaa actttttttg taatatagtg tagtataaaa ttataatatt acagatattt
    33301 aatagttatc ttctgattac tttcattaaa aacagcttca tcactatgaa aatctaggtt
    33361 tttaaacttt taaaaaagtt aaaaaaatat ttttctaata ctcaatttga ttacaatttt
    33421 tttacaattt aaaaaatatt ttttccaaat ttttatatta atacttgact ttgtctgttt
    33481 tataaactag aataattaat aatattaaga atattgaaag gcattgatta ggaagagtaa
    33541 atctgaatcg attaccagag aaggaaacta ctagctgaaa tgtttcccta attagaagga
    33601 ttgaaaacta cctaggagct tctatccgaa gttatcttaa tgattttagt aggaatagac
    33661 gtttttatta cttgcgttaa agtatcaagt ggatttttta aaatcaattt gggtggaacc
    33721 gcgggaaaca gattctcgtc ccttttttag ggatgagggt ctttttttat tacctaaatt
    33781 cagtttttaa aatattctgt atctaattta attagctaat taaaaattta aaatatatgg
    33841 aggattataa aaaatgtatt attcaagtac gagaggcacc gaagaaaaag taactgcatc
    33901 acaagcaata ataaaaggaa tatcaagtga tggtggtctt tatgttccaa gtgaatttcc
    33961 caatgtaaaa aatgaactta taaatttagt aaatttaacg tattctcaga tagcattttt
    34021 tgtacttagt aaatttttat gtgattttac tgaagatgaa attaaaaatt gtatagaaaa
    34081 tgcatatgat gaaaagtttg attgtagtag tatagctcca ttaaataaag taaatgatac
    34141 ttatttctta gaactatatc acggtccaac tttagcattt aaagatatgg cacttactat
    34201 aatgcctcat cttcttaaaa catctataaa gaaagataat ttagagaaag atgttgtgat
    34261 tcttactgct acatctggag atacaggcaa agctgcactt gagggattta aagatataga
    34321 taaaataaag ataattgtat tcttcccaga agatggtgta agcccagtac aaaaacttca
    34381 aatgaaaact caaactggaa aaaatacata tgtagttggt ataaaaggaa attttgatga
    34441 tgcacaatca ggtgtaaaga agattttttc tgataaaaaa tttaatcaaa aactattgga
    34501 taataattat atattatctt ctgcaaattc aattaatata ggaagacttc ttccacaagt
    34561 tgcatactat ttttattcat atatgaaatt agttagcaat agtgagataa atttaaatga
    34621 taaaataaat tttgttgtcc caactggtaa ttttggtaat attctagctg gatattatgc
    34681 caaacaaatg ggtcttccaa taaacaaatt gatatgtgca tcaaatgata ataatgttct
    34741 ttatgatttc tttaaaactg gtgtatatga taaaaataga acattgaaat taactacttc
    34801 tccttctatg gatatattaa tttcaagtaa tttagaacga ttactgtttg aaatatcaaa
    34861 tagaaatact gatattgtaa ataagctgtt atcagacctt agtgataaag gagtctacaa
    34921 aataagtgat gatatggaaa aaaatttagc ctcattctat ggagaatatt caaatgaaga
    34981 agaagttaaa agcacgataa acaatgtgtt taaaaattat aattatttga tagatactca
    35041 tactgctgtt gcatacaatt gttatgaaaa atataaaaaa gaaacttctg ataacacaaa
    35101 aactgttatt gtaagtactg caagtccatt caagttttct gaagatgttc taaagtctat
    35161 agattgtgat tttaaagacc ttgatgactt tgctataatt gatagattat caagtatttc
    35221 taaaatagat attccaaaac ctattaaaaa tcttaaaaat gcagaaatac tacataaaga
    35281 tatttatgaa aaagatgaat taaaactagc tataaaaaaa ttcttaaagg tataggtgat
    35341 tattatgtta gagattatag ttcctgcaac aagtgctaat ataggtccag gatttgattg
    35401 tcttggaatt gcgttaaata tatacaataa attttatgtt gaagaaattg aaagtggtct
    35461 tgaaatagaa ggttgtgaag atgcttacaa aaacgaaaat aacttagttt atacatctat
    35521 gaagtacttt tttgatagag ttaaaccaga aaaaatacct gctggtatca aaataaaaat
    35581 ccacagtgaa gtacctatat gtagaggtct tggcagtagt gcctcttgta tagtagctgg
    35641 agttatagct gcaaatgctc tatcaggtgc taatttagat aaaaatcaat tattaaatat
    35701 agcttcagaa atagaaggtc acccagataa tgttgctcct gctattttag gaaatatgat
    35761 tgtatctgtt actgataatg agaatataca ttatgatatt ataaaaattc ctgaagaact
    35821 taaattttgt gcaatgatac ctaattttaa gttatcaaca gaaaaagcta gaggtgtttt
    35881 accaaaggaa ataccatatt ctgatggggt attcaatgtt agtagagttg ctttactaat
    35941 atctgcctta ctaaacaaaa actttgacct acttaaagta gcttgtcaag acaaattgca
    36001 tcaaaattat agaggaactc taattgagaa ctacaatgat attgttgaaa aatctgaaca
    36061 attaaatagt attggagtat ttttaagtgg agctggacct actataatgt ctttaataaa
    36121 agaaaatgat gatagttttg tggataatat gaaaaattac ctacaaaaac taaaatctga
    36181 ttgggaaata aaagagttat gttgcgattc taatggagct gttttaaata taatataatt
    36241 atcgtcttct atacaaaata taactactct tttattataa tttgtagtat aataattagg
    36301 actaggtaat aatattaagt attataatct agttctttaa acatgtttac attgaggagg
    36361 gattatcata aaagagttaa taattagaga tttagttgca aaagttccta taattcaagg
    36421 tggaatgggc gttggtatat ctaggtcatc actagctggt gcagttgcta agcttggtgg
    36481 tgttggtgta atttctggag ttcaaattgg atatgatgag gaagattttg aaactaatac
    36541 tataaatgca aatttaagag ctataaaaaa acatatttct aaggccaaag aaatctcaaa
    36601 tggtggtatt attggtatta attttatggt agctatgaaa gaatatgaaa catacgtaaa
    36661 ggaagctgtt aaagctggtg tagaccttat aatatctgga gctggattac ctaataagct
    36721 accatcatta gtaaagggaa gtaatgtaaa aatagcaccc atagtttcaa ctgcaaaagc
    36781 tgctaatgta attttaaaaa tgtgggatag aaaagagaaa actactgctg acttaatagt
    36841 tgttgaaggt ccaaaagctg gtggtcacct tggatactct aacgaggaac ttgataacat
    36901 agattctata gactatgata aggaatttgt tgaaatttta aaggttgcaa atacttatgg
    36961 agaaaaattt ggtagaaaca taccagtagt tgctgctggt ggtataactt ctagtagtga
    37021 tgttaaaaaa tatatagata tgggtgcaag tggtgtacaa gttggtacaa gattcgttgc
    37081 tacttacgaa tgtgatgccc atgagaactt taaaatggca tacataaatg ctagtgaaga
    37141 agatgttcat atagttaaaa gtcctgtagg tcttcctgga cgcgccataa gaaacaaatt
    37201 tatagaagaa gttaaaataa atcgtccaga aataaagaag tgctataatt gtttgattcc
    37261 ttgtaatcca aaagaaactc cttactgtat ttctcaagct ctaatcaatg cagttaaagg
    37321 agatgttgaa aattcacttt tattttgtgg aaatgatgcc tataaaattg ataaattaag
    37381 tactgttgaa gatgttatca atgaattgat ttctgaatta taatttaaag aaaactaaat
    37441 taaaatttta tcaagctaag gagtttaaat acgttattta ttaatcttta taaacatatt
    37501 tatgtcctta gcttttttgt gtcaatttcc ttttattgaa attttaattt gattagagat
    37561 agtattaacc cttataacta atcttctttt acaagtacat tggttatttc agctatatat
    37621 aaagtatgat aatctttttg tggataccat cttccatcta taccttcagc aataaaacat
    37681 tggggttcaa gtttctgact atacattttt ttgcatataa tagccatttt agcttcctta
    37741 aaataaggtg tatcatttaa gtgttctata ttaaatccaa tctgtgatat cttatcctct
    37801 tctctaccag atacctttcc acaatatgaa agctctttac gaaaatcttc atcaaaaaat
    37861 gtaagagaaa atttatctgt attatctata aattccttag tataacgctg tggtcttatt
    37921 actacaaaag caacatcttt tccccacata actccaagtc ctccccagct agcagtcatt
    37981 gtattcactt taccttcatt ttctgctgtt ataagtgtcc aatctttacc tatcaatcca
    38041 aatggattat ttttaatctc ttctgccaaa atctctttaa aatcactcat atctctaata
    38101 acctctcatt ctcttatatt tatattcctt ttattttcgt gataaattat aaatgaagtc
    38161 tagttttgaa aataaaatac ttttttaaat atattattgc aaataagtaa atatatatat
    38221 acactcttat tttttaatat atttaataat ttcactcaga atatatatat tctttactca
    38281 aattaaatat aacttatata ctttatgtgt aaattatggt aaaaatatta tttaatcaaa
    38341 tcaaaacttg atttatatac ctggaaaagg tattatatta aagagtgctt aaaatacgca
    38401 tttcataaat agctatatat aaaataataa ataaggagag tgatgggcaa tggatactag
    38461 tccgttgcgg agagaatttt ttacattttc atcacttaat aatatctaaa atcaaaacta
    38521 atacatatat tcagttatat aaattagtta attaatagat actattaaat gatgagattt
    38581 atataaaact gaataaagga tgtgttgcca tgataagata ttacaaaact atagattcaa
    38641 aattagagaa acttagtttt tttgaagatg gctgttggat aaatcttgtt gaacctaatc
    38701 atagtgaaat caacgaaatt tctaatttat taaatataga tgtagaaagc atagaatctg
    38761 cactagatga agaagaacgc tcaagaatag atgttgaaga caatcatact cttatactta
    38821 tagatatacc agtagacgaa agtgactcta attcttctca ttatactaca atacccttag
    38881 gtattatact aactgaagaa gctattgtaa cagtttgtga tgcacagact aagattttaa
    38941 atgactttat agttggtcat attaaagatt tttttacgtt taaaaagact cgctttttgc
    39001 ttcaaattct tcacaaaaat gcagcttatt acttgcatta cttaagaaaa ataaataaaa
    39061 tgacaatcat aatagagcga gaaatttaca aatcaatgaa aaacaaagaa ttggttcaat
    39121 tattggaatt agaaaaatct ttggtatact tctctacctc actaaaatct aatgaacttg
    39181 ttttaaacaa aatggttaga actgctggta taaagaagta tccagatgat gaagacctat
    39241 tagaagatgt tatagttgaa aatagacagg ctcttgatat ggctaaaata tatggagata
    39301 tattgagtag aattatggat gctttcagtg caattataag taataatcag aataatgtta
    39361 tgcaaatttt aacagtagtt acactaattt tctcaatacc tacaataata tcaggattct
    39421 ttggtatgaa tgtcatcaac atgccatttt ctaataaccc aaacggattt tggataatac
    39481 ttcttattac ctctataata tgtatagtga ttacattttt catgtcaaga aataagttat
    39541 tataaaatat taataaaaaa gccattagaa ttaattgatt tacatttatc ctaatggctt
    39601 ttatatattt aaatctatat aatcttataa tactttttaa ctatcatgtt cttcatctat
    39661 aatcatttca gtttcaagcc cttctagcat tgaatctaaa ctttctttta tatttagtat
    39721 ataaattggt acatactctt cttcatctat tacctcttct tgcaacttaa atggaggaat
    39781 taatacttca tcaaagtcta tatttaaatt gggaaagcct tctactatct cttcacaatt
    39841 atcgtactct tcatttgcta aagaaatgta catatctagg ctctttttat aataaagacc
    39901 tgcaagcata tactcacact tcttacttcc atatttaata ccttctttat aatatttctc
    39961 agcttctgcg tcatcattta attttaaata aatttggcct aaattatata ttgattcaac
    40021 acaaccttgt gctctagcct tttcatacca aaatttagaa tttacataat ctttatagaa
    40081 catatcataa attaatccta ccatatgttg agcgtacaca ttattttcat tggcaggtgt
    40141 atcaaacatc attttagact cttccaattt accttctcta aaataaattc tacctagatg
    40201 tatacgagca ttcatatgat ttttgctact tgccatttca aaatactttc tagcattttt
    40261 tgtatttcct aagctctcat atatacaccc caatctataa ctagacctcg tatctccatt
    40321 ttcagatgct ttcttatacc aacttatggc ttcttcaata ttatttaaat cttcatagat
    40381 atttcctaat ttgatttgac aagatgcatt atttggaatc ctcgaataat acgaaatcgc
    40441 tttttctata tcttgattct gataatataa atccccaaga ttttcaaggg aacttttgca
    40501 tccaacagct atagcatcct cataatattt aatagcattt tcataatctt tttcttcaaa
    40561 atatatacct gccagattat tttttgcttc tgttatatca tcttcagcag ccattttata
    40621 ataagttttt gccttctcta tctcattttc tctattatat aaattagcaa gtctatactt
    40681 agaaagtgta tgattttttt ctattgcttt ctcataataa taaattgcat ctcccagctc
    40741 ttcttttcta tcatatacat atgcaagcct atactcagac ttcacatcat ctctatcagc
    40801 actcttttta taatacttct ctgcatcttc taaattatca tttatttcca taatcatacc
    40861 caagttaaag caacctttca tatgacctga cttgtacaac tgtttatata aacttactgt
    40921 tgatttatta tctttctttt ttccatttaa tattgctaaa ttatattttg catcatcatc
    40981 taaaagcaca gaaccttttt tatagtattc atatgcttca tcatctttct ccaaaaaagt
    41041 atataatacc cctaaattaa aacaagcttt acctaaattc ttgtctgctg ctgtttttaa
    41101 ccatttttca caccttacaa aatctttcat tttaaaatgg catacaccta aattattttg
    41161 tgcttgtaaa taacctaaat ttgctatctt ttcataccaa tatatagcat attcatagcc
    41221 atctaactta tagtacatat tacctaaatc aaaagcagca tcttcacttc cacttttata
    41281 tgccattgaa taccactttt ctgcttcttt aaattgtttt ttactttcat atatatttcc
    41341 taaagtatat tgagatttta cgtaattatc caatgcagca ctcttataca actctattgc
    41401 gctttccatc ttacccatct tttcaaggag ggcaccctta gtatgtacga ctttcgggtc
    41461 attagatata ttttttattt tttttataga aaattttgta tttttcatta ttcgctacct
    41521 acccatttta taaaatatat tctctcaaac attattatac attataatct acaattaatg
    41581 ctataatatt gaatttttac cttttgtcac tatattgtaa cattaaattt taaattttat
    41641 aatcattaga ttttattatg taattggtat ataatgtata tatagggggg acattttatg
    41701 aatttcagca atatttttat ccaagttgca gttttattta taattatttt agttggatat
    41761 tttgtcagaa aattcaactt attagatgac cactgcacat ctaagctttc aactttgaca
    41821 atgacagttt ttttaccatc aatgataatt agctccatgc aaattaactt tgatagtaaa
    41881 atgatacaaa aaatactatt gttattattt acatctttga ttatgtatat agtttcaatt
    41941 ataattgcat ttttattgaa atacatttta aaatgtaatg ataaaaaaga tttgggaata
    42001 tatcagtata tagttgtttt ttcaaatgtt gcttttatgg gttatcctgt aattgaagca
    42061 gttttaggtc atgaagcaat attctatact gcaatattca atttgccttt taacttattt
    42121 tctttcactt taggaattta tcttttatct aaaggcagta caagtagagg tttttcaata
    42181 aaatcactta taagccctgc tacaatagct attgttattg gacttttttt atttgtaaca
    42241 ggacttaggt taccccaatt tataaacgag ccacttgaga tgttgggaag tataactaca
    42301 ccaatatcca tgattatcat tggaagctta cttgctaatt cttcagctct cgattgtttt
    42361 gtcaacaaaa aattatatat agtcactttt ataagattat tggtacttcc tgtgattgtg
    42421 tattttattc taaaaggatg gataaatgat aagatgattt tagctatacc agtagtaatt
    42481 tcttcaatgc ctgctgctgc aaatactgct ataatggcta atcaatatga ctccaatata
    42541 acactagctt cacaatgtgt gttttttaca acactatttt cagttatatc tatacctttt
    42601 ataagtattt tactcttatc ttgatttatt tttttatgta ttatataata acatattcaa
    42661 taaattacaa atataaacat tttattgtag tatattgatg gaattttttc ctagatattt
    42721 gtcaataata tctatatgta ttatagaata ggaggcttaa atatggatat ggatttactc
    42781 tttaaaatag tatttgctat agttgctata ggtgtttctg taaaaatcat taaaactgtt
    42841 gctagtttag cttttaaaat agcgttgata ttgctaataa ttttatttgt atatagaatg
    42901 tttttgtaaa catttaaaaa taagtttttt aatacaatag agaagtaaaa tagattattt
    42961 ttaatgtaaa ttttttatta aagacactct attttacttc tctattagct tctttaaatt
    43021 aaatttttat tatatcttcc cataatataa acatcttcaa attttccatc tctgattaca
    43081 gcatattttt tagttccctc tatttcaaaa cctagttttt tatataaatt taatcccttt
    43141 tcattatcta caattacttc taatcctact ctagttaaca taatccaatt atctgctata
    43201 tctaaaagtt gttccataag cttcttacct actcctcttc cctgataatt ctctccaaca
    43261 cttattccta tttctgcact atgtctcaat cgtggagaag aatttacatg taacccagca
    43321 aaacctatta catctttttc tccattatta ttagtttcag ctacaaacat ataatcattt
    43381 tctcccaaag aagctaacat agcttcagtt ttatcgactc tgtcactcat taatgccaaa
    43441 gtatttctca taacactgta tgttcttcta atttcattaa aagcttgtgc atcttctctt
    43501 cttataggtc ttattgttat atctataggc ttactcatat tggattcccc ctcaaacata
    43561 atctttattt ttaattaaaa ttttacatct ttattttata ctgttcaaat ctatgtatgc
    43621 ttctacctga ggtacatata tcatattatc ttttatatgt gtacttccaa attcttttaa
    43681 ttctgtacct tctttatcct tagttatttt atatctaatg gattccatac cttcaactac
    43741 ttcagcatga aaaaacatac cttcatattg tttaaatcta aaattaaaat tgtctttagt
    43801 aagttttatt atcatatttt tatctactcc ttatataatt gatatttttc ttattattag
    43861 ttgtatatat actgcttatt catattaata tattataact tatcatttat ttagtataaa
    43921 gttataaata gatatattta tacttatttt acaatctttc ttcaattgat atataatatg
    43981 tttatataaa ctaatgtatg tgaggtgaaa tatgagcaaa aaaacaaaat atttttcttt
    44041 aattctcttt cctattgctt tgcttttaaa ttttatagcc agcaaagttc caaatattgt
    44101 tgaaaaatat tactcccaat tcatagataa aataattgta caaatattga gtaaagtttc
    44161 tggaattttc ccattttctc tctatgagat tacaatgtac ataatagtta tatctatctt
    44221 cttattttta tgttgtactt tatctacaat ttttaataag aaaaaaaaat taaacatatt
    44281 tttaaaaaat tccattttaa atatattatc cattgtatca atagtctact ttctttttgt
    44341 agtgctttgg ggaataaact ataataggat tccactagaa accacactta taaataacta
    44401 taatttaaaa aacaatgcct ctatccaatc aaaacaatat agtgttaaag agcttactaa
    44461 attatataaa ttccttgtaa ttaaagcaaa tgaaactaga aaactcacat tacaagataa
    44521 aaatggtatt gtaaaatcta atacagatta taatggtgtc ataaatagag ctcaactagg
    44581 atacgataat atcttggata tattacctag tgttagtggt agttattcta agcctaagta
    44641 tattatttca tcaaatctaa tgtgctatac aggaataact ggtatatact ttccttttac
    44701 aggtgaggca aatgtaaata tagcaatacc tgacttatat attccttgta cagttgaaca
    44761 tgaaatggca catcaaaggg gatttgctag tgaagatgag gctaatttta tagcgtatct
    44821 tacttctata aaacaccccc atattgattt taactattct ggatatattt tagctttaaa
    44881 ttatactgct tcttctttaa gtaaggttga ttataatgca tatgttgata tttctgctgg
    44941 catttcagat tctgtccgta gagatttaaa aaatgaaagt gaattttggc aaaaatatga
    45001 aggtaaaatt aatgaaattt ctaatgagtt taacaattct tacttaaaag ctaatggcgt
    45061 tactgaaggt actcagagtt atggtaaaat ggttgattta ttgctaactt attatgaatt
    45121 atatccatat aactaaacac tacaattcaa aattttattc atatacagct gatattaaat
    45181 cagctgtttt ctatttaaat aaattattta acttcaagca atcttatata atttgatagt
    45241 acttatacta tctgtataac atttctattc taactatttt agttaaaaca tttctattat
    45301 cttttttaat aaatgtttta actaaaattt ttaaaacata aaacttccac attatttcac
    45361 tatctatata aaaatctaaa aattcacata taaaattaca taactaaaaa atcataaatt
    45421 tatagaaaac atatattcaa aataaaaaag catgtatcaa aacttgacac atgctttttt
    45481 attttgaata tataccattt tgtcacaata aaaatttcct tgtaacactg atatttttaa
    45541 acaaaatagt ccttatttaa ttaaattaac attaattaaa ttcgtactca ttttgctatc
    45601 attaaacatt acttatagta attttctaat acactatttg aaacttcctt cccttgaaaa
    45661 cttttcaacc aattctcata tgctgaattt ttccatatac taccatcatt aaatgttact
    45721 tgttttacac aagatataat gtactttaca ccatgctctc cagttgattg tttccattta
    45781 tcaaacaata gaaaggcatc attttgattc ttacctggtg ctattgcatt ttgctttgca
    45841 tattctttct ccatttgttt ccattctttc aaccaatttt ctacccatgc cttgccttgt
    45901 tgtttttcaa acatacttat tatatcctgt ggtggtgatt gttgcatttt tctataagta
    45961 tgtgaatatg attttggaga cacaggagat atgcctgtaa caataccata gtctacacca
    46021 gctgggctaa atccaacact tcctacttcg ccatctgctg ccacattttg agcatcccaa
    46081 tatagctcaa gtggttttcc atttttatca tatgctaagc atgtaatctc ataatccata
    46141 attgcctttt cactgctatt tgttaagctt ataacattgc taggccaatg atatggagta
    46201 tcatcatact gtattttgct attatttata aataatggaa tattctcatt ataaacaaga
    46261 cctttactac tttgaatatc ggatactttc tttgtgacag tacttaccgt acttgctaag
    46321 tatacatttg ttttttctga attggtcgta ctaagagaaa atgttgttgt cgttccagta
    46381 atcagcaaag caacaactaa aataggtaag ctagatattt ttttatatct cacagttctt
    46441 cacctctttt tctattaact tataataaaa caatttacca aaacattaaa atctatgtta
    46501 acataattta ccaactgttc tagtaactat atcctatcat agttactatc aagtttcaat
    46561 actattgatg gaaattttca ctatattaaa tcttttttta attttataaa tttacaatat
    46621 gatttaactc atacatatat agtcaaatta gaatataagt ttcttacatt taatgaagtt
    46681 tataaaataa aaaatgacta gataattaaa tactgtaaat aaaaacttat tacaaaagta
    46741 tttaaaaatc tagtcaatta atatatatat gaattgtata ctataatttt tcaatctctt
    46801 ctagcaactc atcaactaat ttgttaccat caatcattct aactatttca ccctttttaa
    46861 ataaaagacc ttcaccttta cccccagcaa tacctatatc tgcttctctg gcttcaccag
    46921 gtccatttac agcacagccc ataattgcaa cagtgatatt tttttccata ctaccaatct
    46981 tttcttcaac ctcatttaca acactaatta agtctatatt acatctacca catgtagggc
    47041 atgatataac tttaatctta tcatttaaaa gtcccaaact tcttaaaatc tgtttaccaa
    47101 caataacctc ttcaacaggg tcgcctgtta aagatattct aacagtatct ccaattcctt
    47161 taagaagaag tgctcctacc cctatagaag actttattgt tcctttgtga acacttccag
    47221 attctgtaat tccaatatga agaggataat caactttttt tgatattaat tcatatgcat
    47281 caacagtttt ataaatatcg gatgatttta gagatataac tatattatga aaatctaagt
    47341 cttcaagaat cttaatatgt cccattgcac tttcaactaa tgcttcagca gttgcagagc
    47401 catgcttttt taaaagttct ttctctaaag aacctccatt gactccaatt ctaattttta
    47461 aatttctttc cttacatttc tcaactacca tcttaactct ctctctactt ccaatattac
    47521 caggatttat tcttattcca tccacacctt gttctatagc ttcaagggct agcttataat
    47581 cgaaatgtat atctgcaata attggtatat ttacactaga ctttatcttt gctatattct
    47641 tagcagcttt aatatcagga acagcaactc taactatatc acaaccagct tcctctagtc
    47701 tctttatttg agctattgta gcatctgcat ctcttgtatc agtatttgtc atagattgta
    47761 tacttatagg attttctcct cctattttta cagttcctac acttacttct ctcgtctttc
    47821 ttctctcgta actcatattc cacctctata tattatttta tattgaatct ctttaaatag
    47881 taaaatatta taacttacat gtatattata aattaaaaag ctatctagtt aaataagaat
    47941 aaatttcata cataaaaatt aatttattct tatttaaaac tacatagcct attttcttaa
    48001 aatctctaaa aaactaaatc attgaaataa tcttaatata tctttatatg tgataaaaag
    48061 cataaataac attaaagctc caaaaccaac aacatttatc atgccttctt tgtttgggtc
    48121 gagtttttta ccacctctaa cagcttctag taatagcata agtattctcc atccatcaag
    48181 tgctggtatt ggtaatagat ttactatacc taaatttaag cttatgacag ctgctaaata
    48241 cactacattt atgatgcctg tacgagcagc atctgatacc ataccaataa cacctactgg
    48301 tcctgctaca gcattgccaa tccctcctgg tacacgtcct gtaatcattt gacctagaaa
    48361 tgttaacatc tgttttgtca tatctacagt agttttacat gcatttacta ttgacgccaa
    48421 aaagtctttt tctctttgtg gttgaatccc tatttcatac tttccattgt tatttttagg
    48481 tgttacattt acaactttat tacttccatc tctagttata ctaagtttta attctccacc
    48541 agaagaagtg tttattatat ttgcaacttc atcccaagtc ttaacagaat taccattaat
    48601 tttatttatc ttatctccta cttgaagccc tacagcctgt gcaggagtat ctggcattat
    48661 ctttcctaat ttagtcgttg gagaacctat atacaaaaat actggaacta aaagtattgc
    48721 tgctaatatt atattgaata ttggtcctgc tacaatagta ctaaatcttt gtaatataga
    48781 cttgtttcca aaagaatttg gacttatttg ttcttcatct tcaccttcca tgctgacata
    48841 tccaccaatt ggaagtgctc ttatagaata ctctgtatct ttttttacac tatatatctt
    48901 aggccccata cctatagaaa actcatttac tttgatacca cttctttttg caaatataaa
    48961 atgtcctaac tcatgtatta atacaattat actaaatagt attaatgcgg ctattatagt
    49021 cataaattca ccttcctatt tttttatcag atttgcaaca taagctctac tccatctatc
    49081 tgtttctaag atttcttcta atgttggttc gcttatgcta ctatgaactt ctaaagtctt
    49141 ctctatgtaa tatggtatgt cataaaaacc aattttatcc tctaaaaatt cacttactaa
    49201 aacttcattt gctgaattta aaacagaaga ataagttcct cccattttta aacactcata
    49261 ggccaatttt aaacatggaa aagtttctaa atctggttct tcaaaagtta aagtactaaa
    49321 ttttgaaaaa ttcattcttt caaagctact ttccattcta tctggatatg taagagcata
    49381 ctgtattggt agtctcatat ctggacaccc taattgagca attattgagc tatctgcata
    49441 ctgcaccatt gaatgaatta tgctttgtgg gtgaactact acatctatat tttcttgttc
    49501 taccccaaac aaccatctag cttctatcac ttcaagtcct ttattcataa gcgttgaaga
    49561 atcaatactt atttttcttc ccatactcca atttggatgc ttcaaagctt catttttagt
    49621 tatatttaca agttctccct ttttctttcc tctaaatgga ccaccagatg ctgtaagtat
    49681 tatcttttct atattttttt tattttctcc atttagacat tgaaatatag cactatgttc
    49741 actatcaaca ggaagaatat ttacattgta tttttctgct tctttcatta caagttcacc
    49801 agcagttacc aacgtttctt tattcgctaa tgctatgtct attcccttct ttatagcaca
    49861 aagagttggg actaatccta tcatacctac tacagcagtt aaaaggacat ccacttcatc
    49921 aagtgatgat attattttta atccttccat tcctgctaaa acttctattt ctatattttt
    49981 aggcaacatt tcttttaatt tcaatgcctt attttcctca aaaactgtta catatttagg
    50041 tttaaactct actatttgtt ctagcaataa ttcaatatta ctgttagctg atattgcaac
    50101 tatctcaaac ttatctctat gttctctaac cacatccaaa gtttgtttac ctatagagcc
    50161 tgtagaacct aaaattgata tctttttcat ataataatcc tttctaataa taaatatacc
    50221 ctgtcaaaac attataacac tactaaaaca attattttta ctattcatag aaatttcata
    50281 tattattcca cagattaaaa ttaatctatt attttttgta tcttgtggaa tattataaaa
    50341 tattctagta ttattaaatg ccctttttta tttccacaac atcttctatt ttacagtcta
    50401 gtgctaaaca tatcttctcc attgtatcca tagaaacaga tttatcattt cctagtctgc
    50461 ctaaaacaga aatacttata cctgatatat ttacaaattc cattttcttt atttttctgt
    50521 caattaacaa tttccataat ggagcgtatg aaatcatgtt atcacctcgc aaaatatatt
    50581 ctatcacatt ttatctattt tggaaaattt tcatctattt agataaataa ttatttatct
    50641 aaatagattt caattatagt ttattaaata taaatatgtt aaaataaaac aaaaccataa
    50701 gttcaaaaat taagctttat atatatttat ctcattattt tactaaaaca taactatata
    50761 aaaaatattt actattatat atctatttaa aacacattat tatagtatca tataaacata
    50821 tgtaaatata taattaaaaa agctaaagat tagtaaattt ataaaaatta tattttgaat
    50881 aaaaggagaa agaatgttgt atttattaaa aattaatcaa tttgaaaaaa gttatgatat
    50941 aggaattttt aaaaatgaac aatcaatata taaatttatt gaaaaaatac cctttgtaaa
    51001 aaaagataat agtaatttta attatacaaa ttactatatg gaatttgaag atattcctga
    51061 atattatgaa gtaaatttca ataattattt atatattatt accaggtttt cattcattcc
    51121 agatggaact gagatatttt ttacttggga agaaatccat tattgggatg aaaaagttgc
    51181 taccgagaaa acttttataa atggcgaaac attagtggat tcatataact ttccaaataa
    51241 tgaagtgaaa gactacatac aaaagcgaga atcattatat atagaaacaa aaaaatatta
    51301 tgaagaaaaa ggattaaaaa ttgagagaca tgcactcggt tcagaagatg gtgaatatgt
    51361 tgaacttaca aatgattcta tactttattt actagatata gaagcagttg aaataagaga
    51421 acaatcaaaa aatatagaag aatttctata taagtacaaa aaacgtttta aataatttat
    51481 attttaaaat acataacaat acattgagtc atttaacgag atataaaatg actcaatgta
    51541 tagactgata aaaataatta tattattttt tagttacata tttgttaaaa aattcttttt
    51601 cttctatcgg tttagagaaa taaaaccctt gtcctacatc acatttaact gtatttaaaa
    51661 attccaagtc ttttttagtt tcaatacctt cacatacaac agacatgcct atacgatgtg
    51721 acatttcaat aatacactga ataatactat atactttctc ccggttaaat gtttctttaa
    51781 gtaagctttt atctaacttc aatccattaa tagatagaga acataaaaga cttaatgaag
    51841 agtatcctga tccaaaatca tccatcgaaa ttaaaaatcc taacttttta agctcctcta
    51901 aaatcgaaat aactggttga gatatttcat taaaagcact ttcagttacc tctatctcta
    51961 tatacttaaa aggaatttca tattctttaa cagtatctaa aaacctttga taaaaactat
    52021 tttggtaaat agtaaccctt gaaaaattaa ctgcaatcgg atatgtatat tgattttttt
    52081 tcataaacgt tttttttaca aatgaacacg ctttttttaa catataaaag tccaattcaa
    52141 taataaatcc acttttttca aacaatggaa taaattcatc tggtgataaa aaaccaagtt
    52201 ctggagaaaa ccatcttaca agagcttctg cgctcacaac atttaaagaa gatatttgaa
    52261 atttaggttg caaatacata tgaaattctt cattttctat cgctttatac atataattat
    52321 aaatactatt ttccatttgt aactgtttta acagattttc attataccat actgtggagg
    52381 aaattcctct tgttttactt accttgtgtg caatatttgc cttatccatt atagaattga
    52441 tagatttata acctaaatta tcaatttcaa ctaagtacgc tcctatacaa taagatatag
    52501 tttgagttac attcatatct aattcagaga ttatagcatt agttagcatt tcccgaatat
    52561 cctctaaaag agaatctcta tattttgcaa gtattacaaa attatctgaa ccaattcttg
    52621 cacaagtttc tttgatatta aaagttttag aaagtgcagc tgcaactatt attagaactt
    52681 tatctccata ttcatatcca tgtgtatcat taatatattt aaaattgtca atatcaatat
    52741 ttagcagtac atactctttg ttagatgcat tgtacaaaat ttcaatcgct ctgttttcaa
    52801 atgcaacctg attttttatt tttgttaaat tatcagtata aaatattctt ttaaaccttt
    52861 ttttattata atattcccaa attaaaagac ttattgttga gaatataaga taaataaata
    52921 gtgcagtagc aaaagaatac aattttgcat tagagtgttt ttcagatata aaaacaattt
    52981 gattagacaa cacagaatac tcttcactca atttatataa tttatcacct gaagcaccat
    53041 ttctaacttt tataatttct ttcttcatag attcccatat agaatccatt tgatttagtt
    53101 tttgttgaaa ttctttatta tcacatcttt gaaatccatt ttctccatta cctgttctta
    53161 gctttatcag aatattatcc agtcgtttta tcaagtcatc atttctttca ttattcaatt
    53221 cttgcttaac aaccttttga gtttcactgc gaatagtacc agtgtgactt ataattttaa
    53281 tatgctctat actatgatat agagaaaata taaaaagaat aataataact agccaaatag
    53341 cagaataaat taaaaaatta tattttttct tcattattgt tacctcattt gtaatatata
    53401 taatttgcaa ataatcaatc tcttataaaa aatgattatc aatattttac agtgatatgt
    53461 atttatctta agtagtttaa tcatttatac cctataaatt atacaaattc atcacctcca
    53521 acacaaacag caatatacgt ttttctaaaa tttcttttta aacattcatc aacactatca
    53581 ttaaatcatt tttaaattgc tcaattaatt tactgcatca cttcttttct tataaaatat
    53641 caccccaata atatatttgt ataatgtctt tatgtctctt tttaaatttg gcatatacat
    53701 aatctatatt ttaataaata attaaaatac tatttaccta caatttaact ctttgaattt
    53761 attttatcat attatgtaaa tatattcctt ttttttggta tattacttaa attatatcta
    53821 tttttgtgca ataagaccaa taatttactt atttcttatt aattatattt aaaaat
//
LOCUS       DACTZW010000021        52622 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.021, whole genome shotgun sequence.
ACCESSION   DACTZW010000021 DACTZW010000000
VERSION     DACTZW010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 52622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52622
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.021"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            477..722
                     /locus_tag="JAM15_06440"
     CDS             477..722
                     /locus_tag="JAM15_06440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797897.1"
                     /translation="MNQKKIKISIKMVIIGIFAVIIAFVLSRLFVEYIDELLRSNWQY
                     QLFESESSYIVFANCIMFSNILLEIFLIYICRKFRKI"
     gene            complement(1219..1527)
                     /locus_tag="JAM15_06445"
     CDS             complement(1219..1527)
                     /locus_tag="JAM15_06445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797898.1"
                     /translation="MVFETFEEYLERDAKGYKIVNKNGFFSEFDFYKAVNICLNISIE
                     DAIKSYNILVKSLVMLDKRLGKRRLKNIYEDIEKENNLVKKFYNIRVESENMILKKNA
                     "
     gene            1623..2271
                     /locus_tag="JAM15_06450"
                     /pseudo
     CDS             1623..2271
                     /locus_tag="JAM15_06450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429361.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            2812..4167
                     /locus_tag="JAM15_06455"
     CDS             2812..4167
                     /locus_tag="JAM15_06455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HAT6797899.1"
                     /translation="MDTKISINENMSLGKRFFKYLAPSVVAMWVFSLYTMVDGIFVSK
                     GVGELALAAVNISMPFINFIFAVSLLFSTGASTIIAIYLGKKDIKSANEVFSFNLVSI
                     IILSIIILAITFFNLDRLALFLGATESTIGMVKDYLGIIIFFNGFFIVSYSLEVIIKT
                     DGFPILATVGVIISALTNIILDYLFVIGFGWGVKGAGIATGLSQVFSTIFFLIHFLRK
                     NSTLNFSKFRIDFKTLRKIVFIGFPDSTTELSCGIVVLLFNLSLTKYIGENALIYYSV
                     INYINTLVLMTMMGITQGMQPLTSFYYGAGNIDNVKKLLKMGIKATIIASVAVFAICM
                     AFSGPIVSLFIHPEETMLFNEGVRVFKIFSISFLLVGINVIISGFFVSVEKPSISTVI
                     SLGRGLVIVVFSLISMILIFGGQGIWMTTIVSEFICLILSLVFLKKNFSTLDSNLNKV
                     A"
     gene            complement(4285..4953)
                     /locus_tag="JAM15_06460"
     CDS             complement(4285..4953)
                     /locus_tag="JAM15_06460"
                     /EC_number="6.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphthine--ammonia ligase"
                     /protein_id="HAT6797900.1"
                     /translation="MKEVLKLADEKFVMSFSGGKDSILALNRMLKKGYKPVALLTTIS
                     EEHGKSWTHNLEYNMLKQVSSNIGLPLLVAECGVEGYEESFEKALIKAKNMGATICAY
                     GDIDIESHRKWDTDRCEAVGMKVDLPLWQESREDLVYEFIDSGFCSVVTKVNLKHLGE
                     EFLGKKLTRELVEKIKNAGADPCGEHGEYHTFVVDGPIFKKPVEYEVKRTLIKDGYGY
                     LEIK"
     gene            complement(5020..5448)
                     /locus_tag="JAM15_06465"
     CDS             complement(5020..5448)
                     /locus_tag="JAM15_06465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HAT6797901.1"
                     /translation="MTKLWAIIFALLAGGSTALEAFINGELGKSTTALVATFISLTVG
                     AIFFLASIIVTGDLKCLVSINGFNYKLLLGGVFGGLIIYFTVKAIPNLGVSNTLILTL
                     VSQVLVGFFIDSVILGQETMHLYKYIGVILLILGTFFIVN"
     gene            5555..6148
                     /locus_tag="JAM15_06470"
     CDS             5555..6148
                     /locus_tag="JAM15_06470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797902.1"
                     /translation="MNFCYNCSIDFGGDFMYTNFNIDFNNFNKKENAIKFMLMGVLLI
                     ILGLLCLTFKTLGIKLISWTFGIALLFFAYLNLKNINELKRYATKEEIKPSINIQWVL
                     IIACILLFVFPQKIQSIFSLFLGFYLIFNQLVALVNSKNNPYSKFTTWNIVKILFGIC
                     LILSPLFLSRFIVSIMSFFIILFGLVLFFSGNTARKY"
     gene            6267..7202
                     /locus_tag="JAM15_06475"
     CDS             6267..7202
                     /locus_tag="JAM15_06475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893027.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HAT6797903.1"
                     /translation="MDKFKYAFDNKRYHTWNYYLRNTFGEKVFKVSINAGFTCPNIDG
                     SLGYGGCTYCSKEGSGDFAGNPKDNLISQFYNIKEMMLKKWPHAKYIGYFQAYTNTYA
                     PLEVLKEKYETILELEDVIGLSISTRPDCLPDDVVEYLSELNKRTNLWVELGLQTIHD
                     STSKIINRGHDYKTFVEGVEKLKSKNIKVVVHIINGLPGEDYNMMMETAKAVGKMGVD
                     GIKIHLLHVIKDTPMEKMLQNGMLTLMEQDEYINLVCDQLEILPETMIIHRLTGDGKR
                     DELVGPIWSLKKWEILNQIDDTLKARNSYQGCKFV"
     gene            complement(7467..8411)
                     /locus_tag="JAM15_06480"
     CDS             complement(7467..8411)
                     /locus_tag="JAM15_06480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HAT6797904.1"
                     /translation="MGEKSKGYVFIAIAGLLWATLGLFGKFLMGNGLTSEQVAFTRLF
                     FGFIVLGVYSSIRTPQILKISKKGIIYSVIIGIICQAMFNLCYFKAIDIAGVSIAAVL
                     LYTSPLFLAIFSKLCYKENITRSKLFSLILCFIGAIMAVTGGRLDFQGLNAFGLLLGV
                     LSAIAYALMPTISKNALKEFSSSTILVYSFLFGAIFMIPSSRPWEILNYAKDLDVLSC
                     MLMLGIVPAALAYIFYAAGISKGVELSVAGVVASVELVGSVIIGCTILGESFSLGKLF
                     GVMLMLISAVVALNLSYDEIRIFYKSNKLKQIEKTESI"
     gene            8741..10171
                     /locus_tag="JAM15_06485"
     CDS             8741..10171
                     /locus_tag="JAM15_06485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HAT6797905.1"
                     /translation="MKLDLEFYQKILEASHDEICVSDDKGIIIYCNKAFEENYGLKKE
                     DILGKNVSFLEDSGYSTKSPIPIVLKTKTKFSLEQDTQTGKKLIITATPIFDENGNLE
                     FTVENCRDITELNNIKNKLEDTKKQVKKYKSEVETLYRTALRIEDTVIMDGIVMRPII
                     NTVNHVSKTDVSVLLLGESGTGKSSLARYIHHNSNRSNGPFITINCATISPQLLESEL
                     FGYTSGAFTGASTKGKVGLVELANGGTLFLDEIGDIPQNLQAKFLQLIQDRTFTPVGS
                     LKNKKVDIRIISATNVDLVSKVKEKKFREDLYYRLNVIEIKLPPLRERRDNLVEIIKY
                     YFNRYSSDFNLNKTISKEAMDAIANYRFPGNIRELQNIIQKILLTCTDNHITIDDLPN
                     ILTKNIHIPNNGNKTHISQINKVIISDSKSTNYKNKNFDTLIKEYEKNIILDAYEKFG
                     SSYKVAKHLEISQSKANRLIRKYTNT"
     gene            10371..10955
                     /locus_tag="JAM15_06490"
     CDS             10371..10955
                     /locus_tag="JAM15_06490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc dependent phospholipase C family protein"
                     /protein_id="HAT6797906.1"
                     /translation="MLMNTHFIMAKSILDNIDENKTFFISEKNFIYGNIKPDAFSKYK
                     LKKHYLDESFNMIVSKINYLCSLNIDSLSKYFSVSRLSQELGVICHFLCDFFCVAHSE
                     RWEFKHSLNKHVTYERELGAFAKDVDLSKIKCGTINSSFEKFFTKLYSDYKKKTDYMN
                     DLKFSAYTCNSVINYILDSILSNTIKSYHIANCG"
     gene            complement(11059..11838)
                     /locus_tag="JAM15_06495"
     CDS             complement(11059..11838)
                     /locus_tag="JAM15_06495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAT6797907.1"
                     /translation="MIKHIFCDLDGTLYENGTITKEDIVAIEEIEKKGVQFNVATGRI
                     FKQAHNIIKGSLDMNGYYVCENGSFIYDKDYNVIFKRTIDDNLVKKVIDRFESSDAQL
                     YFKYKGDVIVGSDTTAFRHYSSDFIVDPDFEKRSSFDNLIGNIGVCSENLEELSRIEL
                     YLKSEFSEVLEIYFSGTYTLNIVPKSVSKRGSIEHVIKTLNVSPDEVATIGDSPNDIC
                     MLEGFKYSFAMSKAREDVKQSANYVVDSVKSAIDVIMEINS"
     gene            complement(11908..13164)
                     /locus_tag="JAM15_06500"
     CDS             complement(11908..13164)
                     /locus_tag="JAM15_06500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HAT6797908.1"
                     /translation="MKAEIISVGTEILLGDIVNTNSQFLAKELASLGIEVYHQSTVGD
                     NKQRLLECFDESLKRSDFVITTGGLGPTGDDMTKETAAEYFGQKLELHKPSLEVLESF
                     FVKTGKKMAENNMKQVYFPKDAIVLKNNNGTAPGAILKKDGKFIIVLPGPPREMKAMF
                     NESVKPYLQQFTNEMLVSKTLRLYGIGESNLELEILDIINEQTNPTVALYAKELEVTI
                     RITAKAENEREAFKLIKPVEEKIKSRVGKYVYTEGDISISEGETALEDAVSKLLVEKN
                     LTIAVAESCTGGLVSSSLINYPGISSVFLEGCVTYSNDSKMKRLGVKRDTLEEFGAVS
                     EQTAIEMAEGVAKGLKANIGISTTGVAGPGGGTKEKPVGLVYTAIYINGKTIVKKNIF
                     NGDRRKIRLRATRDLLNELRIQLEKL"
     gene            13422..14321
                     /locus_tag="JAM15_06505"
     CDS             13422..14321
                     /locus_tag="JAM15_06505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HAT6797909.1"
                     /translation="MKIAVIMGGISSEREVSLNSGKEIYNNLDKNKYEVVKVIIDDKK
                     DIFTKIPEDIDFAILALHGKFGEDGCIQSILETMDIPYSGCGPLCSGMCMDKNITKKM
                     LRDSNLPTAPWVLVKSVDEIDYDEIDNIGYPVFIKPNSGGSSVATFFIHSKDEVEEAV
                     RKGLEVDEFVMIEKYIPGGEYTSFILNGEVFPTISIKSDSGFFDYEAKYSVEKGAKEE
                     VVYLDEELQKRVNEISETCWKIFNCKAYVRVDMIISEGIPYVLELNTLPGMTQTSLIP
                     RSAAARGIKYSELLDKLIEYSLN"
     gene            14345..15793
                     /locus_tag="JAM15_06510"
     CDS             14345..15793
                     /locus_tag="JAM15_06510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAT6797910.1"
                     /translation="MIFSNLKLNDNEPIYIQLKNYISDMISKGLIPDNSKLPSTRELS
                     QLLQVSRNSVVLTYEELKSEGLIYSISGKGTFVKSKNKSSNTTWSLNWDCLENTYSKK
                     ANELDIIKSEIPWSSDLISFKSISPDGDLFDMEELKKSFLNRISLEGHKLLNYGYAQG
                     YKPLIDYLLEYMTNKGVDISNKDILITNGFTEGFDIIMSSFTQEKDYIICENPTHNTA
                     IKIMKSHNLNILGVDINEDGLDFNMLEDNLVKYKNKIKFAYITPSYHNPTGIVMTPEN
                     RYKFYNLMKKYNIAIIEDGFNEELLYNSSHIFPICSLDNMNNGVVYIGSFSKILFPGM
                     RIGWIFADKKVINKLESVKRCRNIHVSFLDQGILFDYLSNGGFEKYIKKIRKFYGDKF
                     NFAYKCIKKYIKTEYILGDGGLHIFIKLKNIDTRVLLEKCYEKNVIFMPGDLFFTDNS
                     GFDTLRLGFSRLSFEDIEIGIKIIGETINEMF"
     gene            15876..16658
                     /locus_tag="JAM15_06515"
     CDS             15876..16658
                     /locus_tag="JAM15_06515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797911.1"
                     /translation="MSKKSKRRKINKLKLTIVITVLFLALLSIYEILFSNPNKKGNIK
                     SQETMQNKNNTTDDSKNNQSSTKKQEDNNIKPTFSYSSIPDNIKNKMIGKSMPTDEPI
                     SFDSLSYLKLTYYGFDEKTHQGEMIVNSELAPEVVDIFKELYEKKYPIEKIKLIDDYD
                     AVDEKSMSDNNTSSFCYRTIAGTNVVSNHGKGRAIDINPLQNPQVSGNDVTPKISTVY
                     ADRSSTKFGMIKKGDDCYNAFVSRGWSWGGYWKNPDYQHFEK"
     gene            16684..18603
                     /locus_tag="JAM15_06520"
     CDS             16684..18603
                     /locus_tag="JAM15_06520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006785143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAT6797912.1"
                     /translation="MNLMTLENISKSYSEKKLLENISLGINEGEKIGLIGVNGTGKST
                     LLKIIAGVEESETGNITKTNGIRIEYLPQNPTYNENSTVLEQVFNGTSEELKLLGEYQ
                     EILEKLNSNFTEELNKKLLSVHEKIDALNLWDLESEAKSVLTKLGINDFNQKIAELSG
                     GQRKRVSLASALITPCEFLILDEPTNHLDNDTIDWLEEYLNSRKGSLLMITHDRYFLD
                     RVTNRIIELDKGRLFSYDGNYSIFLEKKMERLSLEASIEDKRQNLIRTELAWVKRGAQ
                     ARSTKQKARLQRFDELMNRDSFKPDENLDISVASSRLGNKIIEIHNISKSFEENTVID
                     NLEYTLTRTDRIGIIGKNGMGKSTLINILNGEIEPDSGYISIGETVKIGCFSQDDSHM
                     NIDMRAIDYVKEASDYIETSDGTRITASQMCERFLFNGTMQYTLIGKLSGGERRRLHL
                     LKILMTAPNVLLLDEPTNDLDIETLKILEEYLDEFKGVVVTVSHDRYFLDRICNKIFA
                     YEGNGKIHIYTGNYSDYLIYREIQGIEFEESKRESVKKDDSTTLKKEKPKNDKKLKFS
                     YNEQREFENIDSDIEKLESKIATLDESTAKFSTDFTKLQEILDEKSKLEKELEYKYER
                     WEYLNNLADEIANNK"
     gene            complement(18845..19192)
                     /locus_tag="JAM15_06525"
     CDS             complement(18845..19192)
                     /locus_tag="JAM15_06525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012102390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PqqD family protein"
                     /protein_id="HAT6797913.1"
                     /translation="MSKSNDVLDIVFKITDGLEYEVAENSVVTILEKQDHKIQKFFRK
                     LKARIPKYKKIELDEYSSFVFLQIDGQRTVREIGKNLEAKYGEESHPLYERLLVFLNH
                     IEVNCHYIERLDI"
     gene            complement(19179..21107)
                     /locus_tag="JAM15_06530"
                     /pseudo
     CDS             complement(19179..21107)
                     /locus_tag="JAM15_06530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902476.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide transporter, OPT family"
     gene            complement(21517..23706)
                     /locus_tag="JAM15_06535"
     CDS             complement(21517..23706)
                     /locus_tag="JAM15_06535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HAT6797914.1"
                     /translation="MYEVNLERAMNYWMDLLDDYTNIAKIPNDFFYKDCSDEVVDEVF
                     KMNIEKHERLIQYSKVNNISIDSIIETIYGLILQKYIYEDDVVFGKTMNIIPIRVRVR
                     QSEKFIDVVRKLKRQWSRSLEYGYYLLSDIENKNHLNTKLINTIFIAKSFDLSYDYDI
                     EKKGYDLSVIVYTKRALKIKIKYKPSIYKRETIRRILNQFDYIIEQIIEDNDILIEDL
                     EFVCKEEEKVLLEDFNNNQYEVPYDKSYVDLFREQVKVTPSNIAARDENRKLTYKELD
                     EVTDKLAGYLNHIGVESEDIVAVMLPRDINIIITAIGIMKSGGAFFPIDTSNPEERLN
                     YLLEDSNAKVVITTDELKSKVVNENTIVLDINDEEMFKLGYELTEKITSSNCAYTIST
                     SGSTGRPKTIAIEHKSLVNMCYYSVKSISATENDICGIYLSFSFDAVMKQLFPYLLVG
                     ASIDIMPEEAKFDEYTVNEYCEENDITILALPTAFARLFIQNCNNNSLRVVQTGGERL
                     KGYRKRNYELYNEYGPTEFTVVSTSFHVDREYGKIPIGKPIFNTYAYVLDKKNKLCPI
                     GAPGELCLSGIQISRGYLNKKGLTEQVFVENPYKTCEHNKLMYRTGDLVRWLDDGNLD
                     YIGRMDNQVKIDEFRIELYEIENIINNITEIKSVVCISRTNDDGDMYICAYYVIDEED
                     SGKINERTIREYLNEHLPPYMIPTIIMRIDKIPVTPIGKVNKKALPE"
     gene            24037..24768
                     /locus_tag="JAM15_06540"
     CDS             24037..24768
                     /locus_tag="JAM15_06540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAT6797915.1"
                     /translation="MNIYAHRGFSGKYPENTILAFKKCLYMDIYGIELDVHRTKDGKI
                     VVIHDEKVDRTFNGHGFVKDFTLRKLKTLNSSFEGYQNNKECKIPTLEEVLILISPTD
                     LILNIELKTDKINYPNIEKDVLELILKYNMKNRVLISSFNSNSLKNFHKLDPSVKTGL
                     LCYLPINNVVNFAKFLGNSYLHPPLVLVNESLIELCHKNLLGVNVYTVNEEDDILHCL
                     KLNVDGIFTNYPDIASNLLHSKQYS"
     gene            24848..25483
                     /locus_tag="JAM15_06545"
     CDS             24848..25483
                     /locus_tag="JAM15_06545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAT6797916.1"
                     /translation="MDNLLNELEALKSNLDNLPIEKIENYDLSKTALFIIDVNNGFAR
                     QGALYSPRVESLIKPIEMFTKKISNKLNRVIAFTDSHTPKSIELLSYPVHCLENDVES
                     ELVDELKSIENLQILPKNSTNGFFALENLDFDNIDNIIIVGDCTDICIYQFAITLKSY
                     FNQHNIEKNIVVPMNLVDTYDIPNIHPAEILNLVFFNSMIQNGVNVLKEIR"
     gene            complement(25734..26327)
                     /locus_tag="JAM15_06550"
     CDS             complement(25734..26327)
                     /locus_tag="JAM15_06550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3867 domain-containing protein"
                     /protein_id="HAT6797917.1"
                     /translation="MSDDRIIDFNELKNKVKDSDVDKFEQYIYNLYFSVMDGKMSMAE
                     FSRKIFDYMRDNNISQEKFMKIQKQFMERYGMDTEEVEKQLRNFGIDPSTAGFMSNNT
                     SSKVSTEDLESFKKSAGFYEKYGEKIQPKSCITTFIKNDLNDINVIIDQEKIMLCSDR
                     KINLMDSELNEFLLEYKNMFNKKIKVVMCETTNKYDY"
     gene            complement(26398..27261)
                     /locus_tag="JAM15_06555"
     CDS             complement(26398..27261)
                     /locus_tag="JAM15_06555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HAT6797918.1"
                     /translation="MLGIIAPSGPLRNTSLEEIKFNLESYGYEVKFSESCSLNYKGYL
                     AGNDDIRARDIEDMFLDKDVDIIMCLRGGYGTTRILDKINYDIIKQNPKPFIGFSDIT
                     GLNLAFYKNCGLLPYHGIMAANVGKWDKFTYKSLVNALEFKDDLYLENPKEEKIYTVC
                     EGKAEGIIIGGNLSLIIATMGTKYEIDAKDKILFIEEIGEPQYKLDRMLTQLYSSGKL
                     EECNGIIFGDFKDCIEENDLMELLIEFANKVNKPSIYNLQSGHCIPMITIPLGRMCEL
                     DATEKIVKLKK"
     gene            27424..28593
                     /locus_tag="JAM15_06560"
     CDS             27424..28593
                     /locus_tag="JAM15_06560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HAT6797919.1"
                     /translation="MLNIRTLCHEINDWIINIRRDLHKTPELGLEEFQTKKKIIKYLN
                     EIGINYIEYKNHTGITAYINVSPNFETVAIRADIDALPITEELNYSYKSINIGKMHAC
                     GHDAHTAILLGTCNILFKLKNYLNVNVKFFFQPAEETIGGAQLMIEDGCLENPNVKYI
                     FGLHVNPNINKNLIELKYNTLNASTDTLQLTVHGSKCHGAYPHQGIDAIVISAHIITA
                     LQTIVSRNTNPTDSVVISLGKIEGGIKENIVCDKVVIRGTLRTLTPETREFSKKRIRE
                     ICDFTCKTFGGSISVEIEEGYPALINSNHLVDYVKQNAVELFGEENIILKDSPTLGAE
                     DFSYFLRHCEGAFYHLGCANREKNITSPLHTSTFDIDEDCLITGVMLHVKNVLSF"
     gene            28694..29170
                     /locus_tag="JAM15_06565"
     CDS             28694..29170
                     /locus_tag="JAM15_06565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014902865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HAT6797920.1"
                     /translation="MKEILINPIGKICIQGEEVFIKLDKKYVPALNELDDFSHLNVFW
                     WADGFDNPELRSILETPKPYKSGPDVIGIFATRSPIRPNPIALTAVQIINIDHENGII
                     KIPYIDANDNSPVIDLKPYTPSVDRIENPSVPKWCSHWPKSVEKSGEFNWENEIEF"
     gene            29736..30530
                     /locus_tag="JAM15_06570"
     CDS             29736..30530
                     /locus_tag="JAM15_06570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid amidase"
                     /protein_id="HAT6797921.1"
                     /translation="MKLYLSADIEGTCGIVNWDETKLECEFSQHYRTQMSKEITAACD
                     GATQSGVHEILVKDAHDSGRNINPNILPENVKILRGWTKDPLVMMAGIDESFDACIFT
                     GYHSGATCNGNPLSHTMDIDYDYFKINDEIASEFTINAYIAAYYNVPVAFLSGDEMLC
                     ESAKKLNPNIVTVSVSKGIGNGSISIHPNLALKKIEKGVKKALSGDLSRHLIKLPDKF
                     KIEIKFREHYKAFKASFYPNMKKIDSQTVLFETEDYYEFLRMLLFI"
     gene            30554..30997
                     /locus_tag="JAM15_06575"
     CDS             30554..30997
                     /locus_tag="JAM15_06575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797922.1"
                     /translation="MIKISNKRRIPLGEFISVFLFFAVFFGITFCIFTVIGIGFLSFL
                     GFEYKSLGAVLIFFLIYFCITTPIDFLCTTILDIFRYVNKLPYSIYKLCEFIIDFILT
                     FLAMNIIDTFMDSVTIPLSTEILFALLSYLLSECMDFFDRDKKKP"
     gene            complement(31086..32372)
                     /locus_tag="JAM15_06580"
     CDS             complement(31086..32372)
                     /locus_tag="JAM15_06580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAT6797923.1"
                     /translation="MEKVKVAVIGAGNRGTYAYAPYIYENSDVCEIVAVAEPKKGRRE
                     LFTQKYNLDSKNVFETLEDFFKHDKMADAVIIATNDDRHYDVAKLALEKGYHVLLEKP
                     MSNSLDGLVHIDDLCDKYKDKIFMICHVLRYSPFYNKLKEIVESKKLGELVSIQYNEN
                     IGYWHFAHSFTRGNWRNSNETSPLILAKSCHDMDILLYLVGSRCKKISAFGSLKHLNN
                     QNASGEMAQNCLQCLVEKKCPYSAKRIYLEKDRSINRAVHINPTEENLLNILKTSPYG
                     RCVYRCDNNVVDNMVNILQFENGVTATFNLCAFTKENGRTIKLMFSHGEVGGDLNKNE
                     IRIKEFGKNEEIVMNPSNQQNMVEEYDRNLIAEFIKLVSNKELEKGRVAAKEAIQSHV
                     MAFAAEYSRVSDEVVYIEEFFDSAKQMTKEIEETIF"
     gene            complement(32590..33480)
                     /locus_tag="JAM15_06585"
     CDS             complement(32590..33480)
                     /locus_tag="JAM15_06585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HAT6797924.1"
                     /translation="MSSTIKSNRIKGIMFIIASALGFAMMSAFVKLAGDLPSFQKVFF
                     RNLVSAIIAFWLIIKHKGSLTGKKENLKVLLYRSIFGTLGVIFNYYAIDKLMLSDANM
                     LNKMSPFLVVIFCAIALKEKINVKQIGAIIIAFIGALFIIKPTFSVEVIPYLGGIAGA
                     VFAAMAYTCLRVLGDREDYYTIVFFFSVFSLVTVGPIAFAVYEPMTLMQLIYLLLGGV
                     FASLGQFGITLAYKYAPAKEISIFDYSNIIFSAILSIFLFNVYPDMLSVVGYLIVFSA
                     AFYMFLYNKKLDKLDKEKKK"
     gene            33772..34116
                     /locus_tag="JAM15_06590"
     CDS             33772..34116
                     /locus_tag="JAM15_06590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HAT6797925.1"
                     /translation="MEIKRYEGTGRMSRAVVHNNTVYLCGQTHAEGGVIEQTTEVLAK
                     IEDLLNKYGSDKQHLLSVTIYLRDMKDFEAMNSVWDAWVEKGFEPARACVEARLAREH
                     LLVEMSVVAATK"
     gene            complement(34275..36371)
                     /locus_tag="JAM15_06595"
     CDS             complement(34275..36371)
                     /locus_tag="JAM15_06595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CocE/NonD family hydrolase"
                     /protein_id="HAT6797926.1"
                     /translation="MIKFKLYISGLYSGNVIFDGDLLIEKLNPFTNKIESLKTISKEE
                     NTYYLNLTKIDLKSLFNNFDVYTKSLVNTDKDTVINNLGETHSKLNEYIWVQRNKKFP
                     LDIIIVDNKIVGFICLSRETCTILIMDGYEEYTVLKEWEKTHKNEEIYSIRFGGNYMI
                     NMKDGIKLSTDVYLPDFVDSTKKAPTILMRTPYGKENDKEIYYKYVQRGYAVVIQDVR
                     GRNESEGKWEPMIHEREDGDSTINWIVSQEWSSGIVGMLGASYLGYVQWAAASSGNKH
                     LKALVSIVTSGSPFIDIPRKGGAFVSGMLAWAFMVSRNKVDRSKMVRDDWDDVLNIRP
                     IENIPVEALGYRIEFLEEWLKRVEKDEYWDLMDWHLQKDKINVPALVVSGWYDDNSMG
                     TTEALDVIKDYEKGKRKAILGPWMHNSNTLRDINGISLGNSSLRYDLDYNYLLWFDKY
                     LKGIENNIDTTAPVEYYSVGSNKWKTEENWPIINKIDKSMYLISDGNANTSLGNGRLV
                     FDNDLEEKYDSYIYNPKDPSVQLIDMSENEVGVPNNYKDLEKRSDMLCYTSDAFSEEF
                     TVTGDIKLEFFASSSAKDTDWVIKIMDVDLDGNSIKLADGILSARFRNSFYKSEFMEE
                     GEIYKFTIITSKISNTFKVGHKIRLDITSSAKNFIFQNSNTTEGYNSIEYIEAKNTIY
                     HGGKYPSKLILPIENK"
     gene            complement(36384..37544)
                     /locus_tag="JAM15_06600"
     CDS             complement(36384..37544)
                     /locus_tag="JAM15_06600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HAT6797927.1"
                     /translation="MNTLFSNPGSILAVMTSMIALGFYLQRYKAIKSLGPALTIIIMG
                     IILSNLKVVPVSTELYGTISTYAIPVSMTIMLMSVDLKEMTKLSREPLIAIFVAVLTV
                     SIMAFLFGLVFAEKISEGWKVAGMFVGTYTGGSANLTAIGTGLNVSRQTLAAANAADY
                     VIGVPTLIFMFALPAILKNSKKFKKLWPYHVEESELEDCQNEEFMESKEWSIKDIAWM
                     LAIGFVVTEVSTILAGYFNSSFSSAARILLVTTISIIIAQLKPVKKLKGNLDLGLFVA
                     LFFLCTIGFSVDIKEFLGSTFTITLYCFSIIFASFVFHLGITRLLKIKYQYVILSIVG
                     AIADGPTSALVAASAKWNSLVSVAVVMGVIGGVLGNYAGISVAYAIKMSLGL"
     gene            complement(37563..38630)
                     /locus_tag="JAM15_06605"
     CDS             complement(37563..38630)
                     /locus_tag="JAM15_06605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide epimerase"
                     /protein_id="HAT6797928.1"
                     /translation="MKITDIKFEKLRIKLKKPVVVSFGVIEYGESIILKIETDEGYCG
                     FGEAAPLAAVTGEVLDNVLSVLLMFKKELIGKDPLDIETIHTIMDGIIIGNTSAKAAI
                     DIALYDIKGKIMNAPLYKVLGGFDSKVQTDITISIDKPEKMAVEALERVKEGFRILKL
                     KAGINPEDDIEAVKLIREAVGESIRIRIDANQGWNVNSSINTIKKLEEFNVDAIEQAL
                     PHWDLDGTAYIRNKSNTKIMIDESLHSPIDAIKAIKKNAVDTFNIKLMKSSGIYPAIK
                     INNIAEASGVNCMLGCMLETRIGITAAANLIASKKNITEADLDSFMFCEESKDISGGF
                     VMDGDIMNLVNKPGLGIEVNL"
     gene            38982..39548
                     /locus_tag="JAM15_06610"
     CDS             38982..39548
                     /locus_tag="JAM15_06610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAT6797929.1"
                     /translation="MLGEKMRNIRKSKKKTLSDVSKLTDLSISYISQIERDAIEPSLS
                     SLRKIAEVLDTPLYMFMDDNNTDDLVIRKEDRVMMKFPKSEMFYEIVSPMPTTEFTPS
                     ILFVEFELKPESEDAKDYIYHASEEIMVVTSGVVDICMGEKVVRLNPGDSTFIKANVP
                     HKIINPSKDTIARGYGVISPPIWPIKSK"
     gene            complement(39762..40748)
                     /locus_tag="JAM15_06615"
     CDS             complement(39762..40748)
                     /locus_tag="JAM15_06615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-dependent carboxyltransferase"
                     /protein_id="HAT6797930.1"
                     /translation="MGFKVELGGFQTLIQDRGRVGYGQYGVSGCGAMDEYAHRVGNIL
                     VGNSEDEASLEVLMLGPTITFDEYTQIAVTGGDLGAKINGKEIQNWRSYQINPGDVLS
                     FRGVKSGARAYVSIAGGIDVPLAMGSKSTYTRAKIGGFEGRALKKGDYINTFIQEKDF
                     TINKKLNSKYIPTYSSEIVLRIVKGPQFDAFSNGEVEKFLSNKYKVTNEIDRMGCRLD
                     GESIKHLNGADIISDGISYGAIQVPGHGKPIIMLSDRQTSGGYTKIGNVISVDLYKLA
                     QAKPNDVVKFELVDIYEAHRLLREQEDKIQDIYKSMKNIRVVKAKVLNDIAV"
     gene            complement(40778..41473)
                     /gene="pxpB"
                     /locus_tag="JAM15_06620"
     CDS             complement(40778..41473)
                     /gene="pxpB"
                     /locus_tag="JAM15_06620"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HAT6797931.1"
                     /translation="METRYLISGDKAVVAEFGNEISEDINKKVISFMRAIEISNLKGI
                     VTEMVPTYRSLMISYNPLEIDFDSLIENLKKIEDNLESIVLPKPKIHEIPVCYDEVFG
                     IDIKNVASYNNLTVDEVIKIHTSREYLIYMLGFTPGFPYLGGMDERIATPRLEVPRTK
                     IYGGSVGIAGSQTGVYPIDSPGGWQIIGRTPLKLYDENREEQILLRAGDFIKFVPITL
                     DEFIEIEKNNLSI"
     gene            complement(41493..42713)
                     /locus_tag="JAM15_06625"
     CDS             complement(41493..42713)
                     /locus_tag="JAM15_06625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HAT6797932.1"
                     /translation="MSTKNITDKTKNKKDVGALIGAAFIMATSAIGPGFLTQTAQFTQ
                     DFGPNFSFVILITTILFIGAQVNVWRVIGVSGLRGQDIANKIIPGLGYLVAFLVALGG
                     LAFNIGNVGGAALGMNVMFNMNMTLGTVLSGLIAIFVFMSKNSNSLVDKITKFLALGM
                     IIIVGYVAISNHPPVGEAVSRMVKPENPKGLIFPIITLLGGSVGGYITFAGGHRLIDG
                     GITGEENIKEITKSSLLGILVATMMRVLLFLAILAVVSKGLQLDPENPAASAFKFSAG
                     AIGYKFFGLVLWSAAITSVIGAAYTSVSFLKTLNPFIDKYEKYFIIAFIAISTLIMAF
                     IGKPATLLILAGALNGLILPITLGIMLIASKRKDIVGDYKHPTWLLIFGLIVVLISAY
                     TGITSLSSLGALFA"
     gene            complement(42742..43533)
                     /locus_tag="JAM15_06630"
     CDS             complement(42742..43533)
                     /locus_tag="JAM15_06630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LamB/YcsF family protein"
                     /protein_id="HAT6797933.1"
                     /translation="MYKVDLNSDLGESFGTYKIGLDEEVLKYISSANIACGFHAGDPS
                     HMEKTVQLAKKNGVKIGGHPGFPDLIGFGRREMKITKQEAKDYTKYQLGALMAFASSN
                     GCNIQHVKPHGALYNMAAKDKELAMGICEAIYEVDKDIILLGLYNSEMINSAKEIGLR
                     FANEVFADRAYDNNGFLVPRSVEGAVIHDTKHAIDRVVRMVKEGTVETLTGEVIHIKA
                     DSICVHGDNPKAIEFVKEIRKRFELESIEVCPLENIEVCSSENIV"
     gene            44121..44750
                     /locus_tag="JAM15_06635"
     CDS             44121..44750
                     /locus_tag="JAM15_06635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAT6797934.1"
                     /translation="MDKNYTMPIYQKIALDIANKIYTGEIQEDSVLFGRSVLAGKYNV
                     SPETIRRAVKILEDIGVVKSIKGKGVIVLSPDKASSFIKKYRDITNISSYKSTLYNLI
                     DTKSNLENEILDTINKILDYSNRLEIINPLVPVQFTINSNCKYIGQTAAQTKFWQNTG
                     ATIVAIKRGEELIISPGPYIEFLEGDILLVVGDQHIYNSIPMFLYENEK"
     gene            complement(44864..46378)
                     /gene="glpK"
                     /locus_tag="JAM15_06640"
     CDS             complement(44864..46378)
                     /gene="glpK"
                     /locus_tag="JAM15_06640"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HAT6797935.1"
                     /translation="MEKKYVMALDQGTTSSRAILFNKKGEIVKIAQKEFNQIYPKAGW
                     VEHDPMEIWGSQSGVMREVIETAGIRPEEIASIGITNQRETTVVWSRYTGKPIYNAIV
                     WQCRRTSEICDELKNKGLEESIKEKTGLLIDAYFSATKVKWILDNVEGAREKAEQGEL
                     LFGTIDTWLIWNLTRGKVHVTDYSNASRTMMYNINDLEWDEDILRELDIPISMLPLVK
                     PSSYVYGHTDERMLSGAKIPIAGCAGDQQAALFGQNCVEEGTAKNTYGTGCFLLMNTG
                     SNIVKSKHGLLTTIAWGVDGKVTYALEGSIFIGGASVQWLRDELKIIESAKDSEMYAN
                     RVEDTNGVYVVPAFTGLGAPYWDMYARGSILGLTRGAKKEHIVRATLESIAYQTKDVL
                     EAMQNDSKLKLKSLKVDGGASNNNFLMQFQSDILNVDIDRPKIVETTALGAAYLAGLS
                     VGFYIGRNEITSKWSVEKEFNPNMSEEKRCKLYKGWKKAVSRALSWEKEDELDI"
     gene            46621..47163
                     /locus_tag="JAM15_06645"
     CDS             46621..47163
                     /locus_tag="JAM15_06645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAT6797936.1"
                     /translation="MPKILENVKEDILKVSRDMILEEDYSNISIRKIAQRCGISAGTV
                     YNYFNSKQEIIEYITKSEWDLLIRRIEYSNKNTEDYIKKLNIIFTEIRNFINKVHNIQ
                     YNDFLNTFETERFFEMKKHKDDFHEQLSNKVYEALEKESFFNNDKLVCNIIIKMFFSY
                     STYLHIEFEDLKPYIEKLIH"
     gene            47177..49669
                     /locus_tag="JAM15_06650"
     CDS             47177..49669
                     /locus_tag="JAM15_06650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAT6797937.1"
                     /translation="MNHNTSIKNKDSNPKIFLVLTLYLLGIFMGAIDTGIVSPARTII
                     QNSLGVNEKTGIWMITIYTLTYASVIPISGKLADKIGRKYVYLVSIFLFGSGSLICGL
                     SSLFSNFYILLIGRVIQAIGGGGIMPIATAEFGTTFPENKRGMALGLVGATYGIANIL
                     GSSIGSTILSIFGTQNWKWLFFVNLPICLIILIGGVFCIKNNKSESKEKIDKLGTLML
                     ICIIVSLLYGLMNIDFFNFKNSIQDISVYPYLLTFIVLIPIFIFIENRAKDPILSFEY
                     FLNPRILIVLILSLIVGIGMMGMVFVPQYAENALKINAGSGGYFVAILGLFAGIAAPL
                     SGRLIDKFGAKKILLLGFSVSMIGSLYLVLIALKTNTVFSVCVSLIFMGLGMGFTMGT
                     PLNYMMLSNTRLEESNSALATLSLIRSIGTSISPAIMIGFIAHAGLSVQDNIMDLVGK
                     PSTPKIVQLEELENMIDDLKSDPEMAKNLKNVSIPNMNDTSNINMDMTGGKLPKSLLN
                     KVQSADTTNITNITKEISTTMFDEKVPSIITKIQKNVQKGIDGTQSGINGIEDGENKL
                     NSGIKGVQTGIDNMVKARAGINQGIDGVKKGIAGVGKGIKGMEQGLEKQDEAIKELTT
                     AYNKIPTTEKTPTDNENNSNEQNQSNTSNSESDDTKNDSTENKNNNSSENKPNVNEQK
                     ESLNAQIQQLKKTRDDLNTKLQKNKTQKNELSKKLRSMESQKKELQSKLNNSINQKKD
                     MEKSLDTMQQQKKSLQAVLAKTQEVKTEIPKAFDKSKLDYINSIENNRTKIENTLQST
                     LNSGFKQMYITVFCVNLLAFIILLFYKENKTR"
     gene            50090..50488
                     /locus_tag="JAM15_06655"
     CDS             50090..50488
                     /locus_tag="JAM15_06655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAT6797938.1"
                     /translation="MDTLGKRIAYLRNSKKLTQRKLMDILKFENLGKYETGDRKPNCD
                     ILMSIADYFNVTTDWLLYGKENVNVNSSVKEDKEDYLHVTNDEMMILNLYRQLNERDK
                     IKIEGILELKISEYKDLKKHSSNNNEDKMV"
     gene            complement(50705..50914)
                     /locus_tag="JAM15_06660"
     CDS             complement(50705..50914)
                     /locus_tag="JAM15_06660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797939.1"
                     /translation="MCKLDSDGVIECCRAIDDFITALSNIKSLNMERLNTLTKYSSTC
                     SILLKEGNYEGCTIVYRKMLEELKT"
     gene            complement(50946..51155)
                     /locus_tag="JAM15_06665"
     CDS             complement(50946..51155)
                     /locus_tag="JAM15_06665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6797940.1"
                     /translation="MDARKKWIPFLGVQVKQRLIELNMTQRELAKKIGVNENYLSAIL
                     NGRRTGKKYKSSIYQLLNIEYSEDD"
     gene            51454..51873
                     /locus_tag="JAM15_06670"
     CDS             51454..51873
                     /locus_tag="JAM15_06670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6797941.1"
                     /translation="MDTLGERIVYLRKAKNLKQYELEEMLGCDNLSKFERNIRKPNYE
                     ILKSIAEIFNVSVDWLLNGDNLSHKSDLICDSSSNYPLNSINSNEIKLLNNFRKLNDY
                     DKAKIEGMIELKLHEYEKEKDLGKIEYNKNKDEKIDK"
     gene            52101..52556
                     /locus_tag="JAM15_06675"
     CDS             52101..52556
                     /locus_tag="JAM15_06675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797942.1"
                     /translation="MGLRDKFAQSFARSKTMSGPEKKANEIMGKLLLKKAILPIVLMF
                     VIIIAGAMLKINSWVTLGINLVIAVGAFFYIRNSSKKYQNFKPYVGNLISLEKKGKKE
                     YVAIIKQGKLPVKLQIAYGGEDLEHVKKNQMVQISYNPDAKIAILVNRQ"
BASE COUNT        18797 a         8044 c         6482 g        19299 t
ORIGIN      
        1 tatattttat aatatatatt tcttcattta atgcacttag aaaagcaaat aaaatacaga
       61 ttagtacact ttttagagaa aaataaaatt aatacatcta aaatattaaa aaatacttta
      121 gataatctaa agacacatct caaagttttt aactaaatta taaaactaat tacaaatgct
      181 atgtaacgat aataaataaa aaatttacgt cgcttaagca acgtatcgtt gaaatatttc
      241 atgttgccaa ctggttcgta agttggtaag aaaagaacac taattattta gagttctttt
      301 cttagctaca agtggattat aatactttta aatctgtgag aaaatcatat ataataatga
      361 tatgaacaag taaagaaaat acaaaaatga caaaattata aataaaatat tataaaatca
      421 taaggtcata attgttatat tgtagaaaca aagtaaagag agagggtgga taataaatga
      481 atcaaaaaaa aataaagatt agtattaaaa tggtaattat aggtatattt gctgtaatta
      541 ttgcttttgt attatccaga ttattcgttg agtatattga tgaattatta aggtctaatt
      601 ggcaatatca gctatttgaa agtgagagtt catatatagt atttgccaat tgtattatgt
      661 tctcgaatat attattagaa atatttttaa tatatatttg tagaaaattt agaaaaatct
      721 aatatggtca acgtatttcg aatcgaatac ttcatgatta tttagtctat tgtgctagtt
      781 aaagtttaat tcccatataa agtaaattga ttttagtaaa acaaatcacc cctaagggtt
      841 agtttatgga taagtcatcc aaatattaac tctttaattt ttgctataga ttcatctttg
      901 ctcataactt tacttataaa aaatgaaata ttataagcta gaacttttat tctaattcta
      961 gtcataaatc ctagcataga gttacttttt ttatattata aataaaacta tacaacaaag
     1021 ataatattta gtaaaaataa ctttcatttt aactaaactt aaaattcaat tactctctaa
     1081 attgacgttt aggaattagt tcaaaataaa aaagagtgta tatattgaaa ttactacatt
     1141 tcaatatata tactcttttt aaatttctca gttttccatg gaactttact ttatttattt
     1201 ctgtattagt tgtatttttt atgcattttt ctttaaaatc atattttctg attcaactct
     1261 tatgttataa aatttcttta ctaaattatt ctctttttct atatcttcat atatattttt
     1321 taatcgcctt ttacctaatc ttttatctaa cattactaat gatttaacta atatattata
     1381 tgattttatc gcatcttcta ttgagatatt taaacatata tttactgctt tataaaaatc
     1441 aaattcacta aaaaatccat ttttatttac aatcttatat ccctttgcat ctctttctaa
     1501 atactcttca aaagtttcga ataccaagtt attattattc gattttccaa tagtccacta
     1561 taaacaataa taagtttgtt gctccaaatg atgtaacact tgtagaaaga tgttacagat
     1621 atataaaaga tagagaatgt agtttttctc ctaatactat tagaaataga aaaaatatga
     1681 ttaaaaatca aattgaagtt ttctttaaag atatgaaatt aatagatata acaccttcta
     1741 ttttacagtc ttatataaat aacatataca atgagcacat gttaaattaa ataaaaaacc
     1801 aagtcgattt tataaaatca gtattgaaag aatcttatag attaaaagaa atatcagaaa
     1861 atatttgtga ttttgttaca accccaatca aaaaagtagt tcaacttcta agttttatac
     1921 aaagcaggaa actcaattat tattagaaaa atcaaaaaat attcctatag gtataccaat
     1981 ttttttgatg ctaactcttg gattacgttt tggtgaagct gtatcactta tatggtcaga
     2041 tgtagacctt gataaaaaat ctcacatgta aatcaaacat tagtttatgt atacaataaa
     2101 ataatcttca aaggccctaa aacccctaga ttcaaaagaa gattatttgt tcctgatgaa
     2161 cttataagtt tgtttaaagg ggaaaaatta aaacaaaata agttaaaatt acagggtata
     2221 ttgaaaaatg aatttgattt gatatgctta aataaaagat tcaacccgtg agttcaacca
     2281 acttttgttg ttcattttaa aaaactatta agagataata atcctagaga tataaaagta
     2341 catgaattaa tacatgcaaa tgcgactttg atattacttt caggtactaa cataaaagct
     2401 atttataaaa tattagtaca tgcagatata aaaatagcta tgaatatata ttccatattc
     2461 tcacttatta gatgaaatga ataaagaaac atctgaaaat ataagcaaaa tactattcaa
     2521 ataatgttca gttttatgtc aattaaatgt cactcaaagt gctttttttc catttgtcag
     2581 ttaaatgtca cttaaagtac ctttttccta tttgtcagtt aaatgtcagt aatatataaa
     2641 taagatatat ttataagacc cttaaaatca ctattattta ataaaattta taattatata
     2701 ctatttgctg ttgacattgg tattatacca tagtttatca tttatattag aataaaatta
     2761 ttaattaata gtttcgtaat tttataatag atttacaggg agtgataata aatggataca
     2821 aaaatatcta taaacgaaaa catgagtcta ggtaaaagat tttttaaata cctagcacca
     2881 tctgtagttg caatgtgggt tttctcacta tatacaatgg ttgatggaat atttgtaagt
     2941 aaaggagttg gagaattagc tttagctgct gtcaatatat caatgccttt tattaatttt
     3001 atatttgcag tttctctatt attttcaact ggtgcatcta ccataattgc aatctatctg
     3061 gggaaaaaag atattaaatc tgctaacgaa gtcttttcat ttaacttagt atcaataatt
     3121 atattatcaa taattatatt agctataact ttttttaatt tagatagatt agcactattt
     3181 ttaggagcta cagaatctac aattggtatg gttaaagatt atttaggaat aataatattt
     3241 tttaacggat tctttatagt gtcttattct ttagaagtta taataaaaac tgatggcttt
     3301 ccaatattag ctactgttgg tgtaataata tctgctctta caaacatcat acttgattac
     3361 ttgtttgtaa ttggatttgg atggggtgta aaaggtgctg gtattgcaac tggtttgtct
     3421 caagtctttt ctactatttt cttcttaata cattttttaa gaaaaaactc tactttgaat
     3481 ttttcaaaat ttagaattga ttttaagaca cttagaaaaa ttgtatttat aggttttcct
     3541 gattcaacta ctgaattaag ttgtggtata gttgttttac tttttaactt aagtcttact
     3601 aaatatattg gagaaaatgc tcttatttat tatagtgtca taaattatat aaatacatta
     3661 gtacttatga ctatgatggg tataactcaa ggtatgcaac cacttactag cttttattat
     3721 ggtgcaggaa atatagataa tgtaaaaaaa ttattaaaaa tggggataaa agccacaata
     3781 atagcatcag ttgctgtatt tgcaatttgt atggcttttt caggaccaat agtctcttta
     3841 tttatacatc cagaagaaac aatgctattc aatgaaggag ttcgtgtatt taaaatattc
     3901 tctatatctt tcttattggt aggaattaat gtaataattt ctggattctt tgtatcagta
     3961 gaaaaaccat caatttctac tgttatatct cttggtagag ggcttgtaat agttgttttt
     4021 agtctaattt caatgatact aatatttggt ggacaaggaa tatggatgac tactattgtt
     4081 tctgagttta tatgtcttat tttatcttta gtttttctaa aaaagaattt ttctacatta
     4141 gactctaatc taaataaggt tgcttagatg ataagagtag caatatatga aaatatctaa
     4201 ataaaaaata cctattatac aatcttgcaa atattaaacc tttgcaaaaa ttaggattat
     4261 ataataggta ttttatttat gtaattattt tatttctaaa tatccatagc catcttttat
     4321 taaagttctt tttacttcat attctacagg ttttttaaat attggaccat ctacgacaaa
     4381 tgtatgatac tctccatgtt ctccacatgg gtctgcacca gcatttttta tcttctccac
     4441 aagttctcta gttaattttt ttcctaaaaa ttcctctcct aagtgcttta agtttacttt
     4501 tgttacaaca ctacaaaatc cactgtctat aaattcatat actaaatcct ctctactctc
     4561 ttgccataat ggtaaatcta ctttcatacc aactgcttca catctatcag tatcccattt
     4621 tctatgactt tctatatcta tatctccata tgcacatatc gttgctccca tgtttttagc
     4681 ttttattaaa gccttctcaa agctctcttc atatccttct acaccacact cagcaactaa
     4741 taaaggtaat cctatattgc tacttacttg cttaagcata ttatattcta aattatgtgt
     4801 ccatgacttt ccatgttctt cacttatagt tgtcaagagt gccacaggct tatatccttt
     4861 tttcaacatt cgatttaatg ctaatatact atccttacca ccactaaatg acattacaaa
     4921 tttttcatca gccaatttta acacctcttt catctaactt tgttttatta acataattat
     4981 accaaatttt tgagttgcat agcaaattat attaaattgt taattcacta taaagaatgt
     5041 ccctaatatt aaaagtataa cccctatgta tttgtataaa tgcattgttt cttgtcccaa
     5101 aattacgcta tcaataaaaa atccaactaa aacttgggat acaagagtta atataagtgt
     5161 atttgatact cctaaatttg gaattgcctt tactgtaaaa tatattatta gacctccaaa
     5221 tactcctcct aataacaact tataattaaa accatttata gatactagac actttaagtc
     5281 acctgtaact attatacttg ccaaaaaaaa tattgctcct acagttaagc ttataaaggt
     5341 ggccactaat gctgttgtac tttttcctag ctctccattt ataaaagctt caagagctgt
     5401 agaaccacct gctaataatg caaatattat tgcccataat tttgtcatgg acaaacctcc
     5461 ttctatataa ttctattaat agaagtttat gatacaacct attaattaat tactaagtat
     5521 agtttaattt ttatacacta ggctttattt ggatatgaat ttctgttata attgttctat
     5581 cgattttgga ggtgatttta tgtacacaaa ttttaatatc gattttaata actttaataa
     5641 aaaagaaaat gctattaaat ttatgttaat gggagtatta ctcattatat taggattatt
     5701 atgccttaca tttaagacat taggtataaa attaatttct tggacttttg gtattgcact
     5761 tttattcttt gcatatttaa atttaaaaaa tattaatgag ttaaaaagat atgctactaa
     5821 agaagaaatt aaaccctcta ttaatatcca atgggttcta ataattgcat gtatattact
     5881 ttttgtattt cctcaaaaaa tacaaagcat attttcatta tttttaggat tttatttaat
     5941 ctttaatcaa ctagtagcac ttgtaaatag taagaataat ccttattcta aatttacaac
     6001 ttggaatata gttaagattc tatttggtat atgccttata ttatctccac tttttttatc
     6061 tagatttata gtatcgataa tgtctttttt cataatatta tttggactag ttctattttt
     6121 ctctggaaat acagcgagaa aatattaatt attttctcgc tgtattttta tattacttaa
     6181 aatagaattt gtttaagtta tctatttgtg gtaatatgtt ttttgtacaa gctcagcgta
     6241 caattttatt agaaataggt gattttttgg ataaatttaa atatgctttt gataataaaa
     6301 gatatcatac ttggaattac tatcttagaa atacttttgg agaaaaagtt tttaaggtat
     6361 ctataaatgc aggatttact tgcccaaaca ttgatggaag tcttggttat ggcggatgta
     6421 cctattgtag caaagaaggc tcaggtgatt ttgctggaaa ccctaaagat aatcttatca
     6481 gtcaatttta taatataaaa gaaatgatgt taaaaaaatg gcctcatgca aagtatattg
     6541 gctactttca agcctataca aatacgtatg ctcctcttga agttttaaaa gaaaaatatg
     6601 agactatatt agaacttgaa gatgtcatag gtctttcaat atccacaaga cctgactgtt
     6661 tgccagatga tgttgtagaa tacttgtctg aactaaataa aagaaccaat ttatgggttg
     6721 aacttggact tcaaacaatt catgattcta catctaaaat tataaataga ggtcatgatt
     6781 ataaaacatt tgttgaaggt gttgaaaaat taaagtctaa aaatataaag gttgtcgtac
     6841 acattataaa tggtcttcct ggtgaagatt ataatatgat gatggaaaca gcaaaggcag
     6901 ttggtaaaat gggtgtagac ggtataaaaa tccatctatt gcatgttata aaagatactc
     6961 ctatggaaaa gatgttacaa aatggtatgt taactcttat ggaacaagat gaatatatca
     7021 atcttgtctg tgaccaatta gaaatacttc ctgaaactat gataatccat agactcactg
     7081 gtgatggtaa gagggatgaa ctagtaggtc ctatatggag cctaaaaaaa tgggaaattt
     7141 taaatcaaat tgatgatact ttaaaggcta gaaattctta tcagggctgt aagtttgttt
     7201 aatacaaaat aataactata gaaatggtta tataaccatt tctatagtta tttagtattt
     7261 acaaaacaaa atattaattt gtatatttat acaatatata ataaaaaata gataatctaa
     7321 actgtatcta cttatatttt atttgtactg tccactttat tctataaaat ttataaatag
     7381 ttatttttta ataccaaata taatttggta taatttttgt tggactctac aatgtatacc
     7441 aataaatcct ttttaagtat ataattctaa atactttcag ttttttcaat ctgctttaac
     7501 ttgttggact tataaaatat tcttatttca tcataagaaa gattaagtgc tactactgca
     7561 gatattaaca tcaacatcac tccaaatagc ttccctaagg aaaaactttc tcctaatata
     7621 gtgcaaccaa ttattactga accaactaac tctactgatg ccacaacacc tgcaactgac
     7681 agctctacac ctttagatat acctgctgca taaaaaatat atgcaagtgc agctggaaca
     7741 atgcctaaca ttagcataca agataaaaca tctaaatcct tagcataatt taagatttcc
     7801 caaggtcttg aagaaggaat cataaatata gctccaaata agaaactgta tactaatatt
     7861 gttgaacttg aaaattcctt taaagcattt ttactaatag ttggcataag tgcatatgct
     7921 attgctgata ataccccaag taaaagtcca aaagcgttta aaccttgaaa atccaaacgt
     7981 ccaccagtca ctgccataat tgcaccaata aaacaaagaa taagtgaaaa taatttgctt
     8041 ctagtaatat tttctttata acataatttt gaaaatattg ctaaaaacag tggtgatgta
     8101 tatagtaaaa ctgctgcaat tgatacaccc gcaatgtcaa ttgctttaaa ataacataaa
     8161 ttaaacattg cctgacatat aatacctatt attactgaat atataattcc ttttttgctt
     8221 atctttaaga tttgtggtgt ccttatagat gaatatacgc ctaaaactat aaatccaaaa
     8281 aacaatcttg taaatgctac ttgttctgat gtcagtccat ttcccattaa aaactttcca
     8341 aataatccaa gtgtagccca taataaccct gctattgcta taaatacata ccctttactt
     8401 ttttctccca ttttaaattc ccttctattt ttatttagtc aatttacact cttcttttta
     8461 agcaaaaact atgccatctt aaatcaatat atatcgactc taaaacccta gtctttccaa
     8521 taatactaat aaattttcaa tttttttata tttatttttc gcttacttta agttgattta
     8581 gacttatttt aattgtaaaa tgagttatat ataacttatt taaagttaaa atagactgaa
     8641 acttatatat aaatatcaaa ttttaagtat attaatcaat taaacatatt ttaatatatc
     8701 attaaaaatt taggaggaaa atataaaaat gaatttaaat ttgaaattag atttggaatt
     8761 ttatcaaaaa atattagaag cttcccatga tgaaatatgt gtttctgatg ataaaggaat
     8821 aataatatat tgtaataaag catttgaaga aaattatggt ctaaaaaaag aagatatttt
     8881 aggaaaaaat gtttcttttt tagaagactc tggatattca acaaaaagcc ccataccaat
     8941 tgtattaaaa acaaagacta aattttcact ggaacaagat actcaaacag ggaaaaagct
     9001 tatcataact gctaccccta tatttgatga aaatggaaac ttagaattta ctgttgaaaa
     9061 ttgtagagat ataactgaac ttaataatat aaaaaataaa cttgaagaca caaaaaagca
     9121 agtaaaaaaa tataaatctg aagtagaaac actatacaga actgcactta gaattgaaga
     9181 tactgtaatt atggacggaa tagttatgag accaatcata aacacagtaa atcatgtttc
     9241 taaaacggat gtaagtgtac ttttattggg tgaatctgga acaggaaaaa gctcacttgc
     9301 tagatatata caccacaaca gcaatagatc taatggccca tttataacaa taaattgtgc
     9361 aactatatct ccacaacttc ttgaatctga actttttgga tatacttcag gtgcttttac
     9421 aggtgcaagt actaaaggta aagttgggct cgtagaatta gctaatggag gaactctttt
     9481 tttagatgaa ataggagata taccacaaaa tctacaggca aaatttttgc aattaataca
     9541 ggatagaact tttactccag ttgggagctt aaaaaataaa aaggtcgata taagaattat
     9601 atctgctaca aatgttgatt tagtttcaaa agtaaaagaa aaaaagttta gagaagattt
     9661 atactataga ttaaatgtta tagaaataaa attgcctcct cttagagaaa gaagggataa
     9721 tctagtggaa attataaaat attattttaa taggtactca agtgacttca atctaaataa
     9781 aactatttct aaagaagcta tggatgctat tgcaaattat agattcccag gcaatataag
     9841 agaattacaa aatataattc aaaaaatctt gcttacttgt acagataatc atataacaat
     9901 agatgactta ccaaacattc ttacaaaaaa tatacatatt cccaataatg gaaataaaac
     9961 acatatatcc caaattaata aggttattat atctgactca aaatctacta attataaaaa
    10021 taaaaatttt gacaccttaa ttaaagagta tgaaaaaaat ataattttgg atgcttatga
    10081 aaaatttggt agttcttata aagtagccaa acaccttgaa atctcacagt ctaaagccaa
    10141 taggttaatt agaaagtata ctaatactta attttaaatt tgataaataa aaacttaaca
    10201 ctatttacat attgtaaatt tggccattta ctgttattat gaatatggtt gaaattattt
    10261 aaataaatac tgttgactta gtttcatata tttaccatta aacttttatc ataaatatca
    10321 tatcataata atatatttaa taagtctaat aaactatacg aggtgtaaat atgttaatga
    10381 atacccattt tattatggca aaatcaatac ttgataatat agatgaaaat aaaacattct
    10441 ttataagcga aaaaaatttt atatatggca atataaagcc tgatgctttt tctaaatata
    10501 aattaaaaaa acattattta gatgagtcat ttaatatgat tgtttctaaa ataaactatc
    10561 tatgcagtct taatatagat agtctttcta aatacttttc agtaagtaga cttagtcagg
    10621 aactaggagt catatgtcat tttttatgtg attttttctg tgtagctcac agtgaacgtt
    10681 gggaatttaa gcatagctta aataaacatg ttacttatga aagagaactt ggagcatttg
    10741 caaaagatgt tgatttatct aaaattaaat gtggtactat aaatagtagt tttgagaagt
    10801 tttttactaa actttatagt gattacaaaa agaaaactga ttatatgaat gatttaaaat
    10861 tttcagctta tacttgtaat agtgtcataa attatatact tgactctatt ttatctaata
    10921 caataaaatc atatcatata gcaaattgcg gttaacttaa gaatttttaa acttatataa
    10981 acttataatt gaatataatt aaaatgactg ctctatagaa tataatttta tacttctcta
    11041 ggacagtcat tttttatact aactatttat ctccattata acatctatgg cactttttac
    11101 actatctact acataatttg cactttgctt tacatcttcc cttgccttag acattgcaaa
    11161 actatattta aatccttcta acatgcaaat atcatttgga gaatccccaa tagtagcaac
    11221 ttcatctgga cttacattta acgtttttat tacatgctct atacttcctc tttttgacac
    11281 acttttagga actatattta gagtatatgt tccagaaaaa tatatttcta atacttcact
    11341 aaactcactt tttagataaa gttctattct ggataactct tccaaatttt cagaacatac
    11401 gcctatattt cctataagat tatcaaaact acttcttttt tcaaaatctg ggtcaactat
    11461 aaagtcacta gaataatgtc taaaagcagt ggtatcacta cccacaatta catcaccctt
    11521 atatttaaaa taaagttgtg catcacttga ttcaaatcta tcaatgactt tttttactaa
    11581 attatcatct atcgttcttt taaaaattac attataatct ttatcatata taaatgaacc
    11641 attttcacat acataatatc cattcatatc taaactacct ttgataatat tatgtgcttg
    11701 tttaaaaatt ctacctgtag caacattaaa ctgtactccc tttttttcta tttcttcaat
    11761 tgctactata tcttcttttg ttatggttcc attttcatat agagttccat ctaaatcaca
    11821 aaatatatgt tttatcataa attaaaagcc tccaaaaaca attttatatt atagtaacac
    11881 ttcaaatata tccaatatca taacaactta aagcttttct aattgtattc tcaattcatt
    11941 aagtaaatct ctagtagctc ttaatcttat ctttcttcta tccccattaa atatattttt
    12001 ctttactatt gtttttccat ttatatatat tgcagtataa actagtccca caggcttctc
    12061 tttggttcct ccaccaggtc cagctactcc agttgtagat atacctatat tagctttaag
    12121 tcctttagca acgccttcag ccatttctat agctgtttgc tcacttactg ctccaaactc
    12181 ttccaaagtg tctcttttta ctcctaatct tttcatttta gaatcattag aatatgttac
    12241 acatccttca agaaatacag aagatattcc tggatagttt ataagagatg aagaaaccaa
    12301 acctccagta caagattcag ccactgctat tgttagattt ttttctacaa gtaacttaga
    12361 aacagcatct tctaaagcag tctccccttc agatatggaa atatctcctt cagtatatac
    12421 atatttacca actctacttt ttattttttc ttctactggt tttattaatt taaaagcttc
    12481 tctttcattt tcagcctttg cagttattct tattgtaact tctaattctt ttgcatataa
    12541 agcaactgtt ggattagtct gctcattaat tatatcgaga atttctaatt ctagatttga
    12601 ctcacctatt ccatataatc ttaaagtctt agatactagc atttcatttg tgaattgttg
    12661 taagtaaggt ttgacactct cattaaacat agctttcatt tctcttggag gtccaggcaa
    12721 tactattata aatttaccat ctttttttaa aattgcccct ggagctgtac cattattatt
    12781 ttttagtact atagcatctt ttggaaagta cacttgtttc atattatttt cggccatttt
    12841 ttttcctgtt ttaacaaaga aagattccaa aacctctagt gaaggtttat gtagttctaa
    12901 tttctgacca aagtattctg cagcagtttc ttttgtcata tcatcaccag ttggcccaag
    12961 accacctgta gtaattacaa aatcacttct ctttaagctt tcatcaaaac attctaaaag
    13021 tctttgtttg ttatctccaa cagtactctg atggtatact tctattccca atgatgcaag
    13081 ttctttagct aaaaattgag aatttgtatt tactatatct cccaataata tttctgttcc
    13141 tacacttatt atttcagctt tcaaaattta tcactccttg atttatagcc attaagacta
    13201 gtcttaagtt cataacaata attttagcaa aaataataac ataaataaag ttaaaaaatc
    13261 atttaaacat atctttaaac tagattatta ttctaaaacc acacataata taaacttcgt
    13321 atatagtggt actttcatcc tcaactgtta attcatataa ttaagtatgt aaataaaaag
    13381 tttactttaa aataataaaa attaaaatag gagtgtataa tatgaaaata gcagttataa
    13441 tgggtggaat atcatcagag agagaagttt ctttaaattc aggaaaagag atatataata
    13501 accttgataa aaataaatat gaagttgtaa aagtaataat agatgataaa aaagatatat
    13561 ttacaaagat accagaagat atagattttg caatacttgc tttacatgga aaatttggtg
    13621 aagatggatg tatacaatca atacttgaga ctatggatat accatactct ggatgtggac
    13681 ctctttgcag tgggatgtgt atggataaaa atataactaa aaaaatgctt agagattcaa
    13741 acctacctac tgctccatgg gttttagtaa aatcagttga tgaaatcgac tatgatgaaa
    13801 tagataatat aggttatcca gtatttataa aaccaaactc aggaggttca agtgtagcca
    13861 cattctttat tcattctaag gatgaagttg aagaagcagt tagaaaaggt ctggaagttg
    13921 atgaatttgt aatgattgaa aaatatatac caggtggaga atatacttca ttcatattaa
    13981 atggagaagt gttccctaca atatctataa aatctgattc agggttcttt gattatgaag
    14041 ctaaatactc agttgaaaaa ggtgcaaagg aagaagttgt ttacttagat gaagaacttc
    14101 aaaaaagagt aaacgaaatt tctgagactt gttggaaaat ttttaattgc aaagcatatg
    14161 taagagttga tatgattata agtgaaggta ttccatatgt tcttgaacta aatactcttc
    14221 ctggaatgac tcaaactagt ttaattccta gaagtgctgc tgctagaggt attaagtaca
    14281 gtgaactatt agataaactt atagaatact ctttaaatta gatgaaataa tttgaggtgg
    14341 taatttgata ttttcaaatc taaaattaaa tgataatgaa ccaatttata tacaacttaa
    14401 aaattatata agtgatatga tatcaaaagg actaattcca gacaatagta agctcccttc
    14461 tacaagggag cttagtcagc ttttacaagt tagccgaaat tctgtagttt taacttatga
    14521 agaattaaaa tcagaaggat taatctactc tatttcagga aaaggtacat ttgttaaatc
    14581 aaagaataag tcttcaaata ctacatggtc attaaactgg gattgtttag agaatacata
    14641 ctctaaaaaa gccaatgaat tagacattat aaaaagtgaa attccttgga gctctgacct
    14701 gatttccttt aaaagtattt ctccagatgg agatttattc gacatggaag aattaaaaaa
    14761 atccttttta aatagaattt cactagaagg acataaatta ctcaactatg gatatgcaca
    14821 aggttataag ccccttattg actatttact agaatatatg acaaacaagg gtgttgatat
    14881 aagtaataaa gatatactaa taacaaatgg attcacagaa ggctttgata ttattatgtc
    14941 atcttttacc caagaaaaag actacataat atgtgaaaat cctactcata atactgctat
    15001 aaaaattatg aaatctcata acctcaatat cttaggtgta gatataaatg aagatggttt
    15061 ggacttcaat atgctagaag acaatttagt taagtataaa aataaaataa agtttgcata
    15121 cattacaccc tcttatcaca atcctacagg aattgtaatg actcctgaaa ataggtacaa
    15181 attctataat cttatgaaaa aatacaatat agcaattata gaagatggat ttaatgaaga
    15241 attactctac aatagttctc atatatttcc tatctgttcc ctagataata tgaataatgg
    15301 ggtcgtatat attggtagtt tttcaaaaat tttatttcct ggaatgagaa ttggatggat
    15361 atttgcagat aaaaaagtaa tcaataaact agaaagtgta aaaaggtgca gaaacataca
    15421 tgtatccttt ttagaccaag gaattttatt tgattattta agtaatggag gttttgaaaa
    15481 atacattaaa aaaatacgta aattctatgg ggacaaattt aactttgcat ataaatgtat
    15541 aaaaaaatat ataaaaacag aatacatctt gggtgatggt ggtttgcata tatttataaa
    15601 actaaaaaat atagatacta gagttttatt agaaaaatgt tatgaaaaaa atgttatatt
    15661 tatgcctgga gatttatttt ttacagataa ctctggtttt gatactttaa gactcggatt
    15721 ttctaggttg tcttttgaag acattgaaat tggaataaaa ataattggag aaactataaa
    15781 tgaaatgttc taggttaact aaatattgtt agcctagttt atttttatga ggtataatat
    15841 atatagttta tatgaatcta atactggggg ataatatgag taaaaagtca aaacgaagaa
    15901 aaattaataa attaaaatta acgattgtaa taactgtatt atttcttgct ttattatcta
    15961 tatatgagat actgttctct aatcccaaca aaaaaggtaa tataaagagt caagaaacta
    16021 tgcaaaataa aaataataca acagatgatt ctaaaaataa tcaaagctct accaaaaagc
    16081 aggaagataa taatatcaag cctacttttt catattcttc aataccagat aatataaaaa
    16141 ataaaatgat tggtaaatct atgcctactg atgaacctat aagctttgat agtctatctt
    16201 atttaaaact tacatattat ggatttgatg aaaaaactca tcaaggagaa atgatagtaa
    16261 acagtgaact agctccagaa gtagtggata tttttaagga attatacgaa aaaaaatatc
    16321 caattgaaaa aattaaatta atagatgact atgatgctgt agatgaaaaa tctatgtctg
    16381 ataataatac ctcatcattt tgttatagaa ctatagctgg tacaaatgta gtttcaaatc
    16441 atggtaaagg acgtgctata gatataaacc cattacagaa tcctcaagtt tctggaaatg
    16501 atgttacacc taaaataagt acagtttatg ctgataggtc tagcacaaaa tttggaatga
    16561 taaaaaaagg tgatgattgt tataatgctt ttgtaagcag aggttggagc tggggtggct
    16621 attggaaaaa cccagattat caacattttg aaaaataata gattagaaat aaaggtgaat
    16681 tatatgaatt taatgacatt ggaaaatata agtaaaagct attctgaaaa aaaattacta
    16741 gaaaatatat ctcttggaat aaatgaaggg gaaaaaatag gacttattgg tgtaaatggt
    16801 actggtaaat ctaccttact caaaattatt gcaggagttg aagaaagtga gactggtaat
    16861 ataacaaaaa ctaatggtat taggatagaa tatctacctc aaaatccaac ttacaatgaa
    16921 aattcaactg tacttgaaca agtatttaat ggaacttctg aagaattaaa gctacttggt
    16981 gaatatcaag aaatcctaga aaaacttaat tcaaacttta cagaggaatt aaataaaaaa
    17041 ttattatcag tacacgaaaa aatagatgcc ttaaatcttt gggatttaga aagtgaagct
    17101 aagtcagtac ttacaaagct tggtataaat gactttaatc aaaaaatagc agaactttct
    17161 ggtgggcaaa gaaagagagt ctctctggca tcagccctta ttacaccttg tgagtttttg
    17221 atactagatg agcctacaaa ccatctagac aatgatacta tagattggct tgaggaatat
    17281 cttaattcaa gaaaaggctc attgcttatg ataactcatg atagatactt tttagaccgt
    17341 gttacaaata gaattattga actggacaag ggtagattat tcagttatga tgggaattat
    17401 tcaatatttt tggaaaagaa aatggaaaga ctttcgctag aagcaagtat tgaagataaa
    17461 agacaaaatt taataagaac agagcttgcg tgggtaaaac gaggagctca ggctcgtagc
    17521 actaaacaaa aagctcgttt acaaagattt gatgaactta tgaatagaga ttcttttaaa
    17581 cctgatgaaa atctcgatat atctgttgca tcaagtagac ttggaaataa aataatagaa
    17641 atacacaata tatctaaatc atttgaagaa aatactgtta tagataattt agaatacact
    17701 ttaactcgta cagatagaat tggtataata ggcaaaaatg gtatgggtaa atctaccctt
    17761 ataaatatac ttaatggaga aatagagcct gatagtggat atatttcaat tggagaaaca
    17821 gttaaaatag gttgtttttc tcaagacgac tctcatatga atattgatat gagggctata
    17881 gactatgtaa aagaagctag tgactatata gaaacttcag atggtactag gattacagct
    17941 tctcaaatgt gtgaaagatt cctttttaat ggtactatgc aatatacttt gataggtaaa
    18001 ttatctggtg gtgaaagaag aagactacat cttcttaaaa tccttatgac agctcctaat
    18061 gtgcttcttt tagatgaacc tacaaatgat ttagatattg aaacgcttaa aatattagaa
    18121 gaatacctag acgaatttaa aggtgtagta gttacagtat cacatgatag atatttctta
    18181 gatagaattt gtaataaaat atttgcatat gaaggtaatg gaaaaattca tatctataca
    18241 ggtaattaca gtgattatct tatttataga gagattcaag gaattgaatt tgaagaatct
    18301 aaaagggaat cagttaaaaa agatgactct actaccctaa aaaaagaaaa acctaaaaat
    18361 gataaaaagc ttaagttctc atataatgaa caaagggagt ttgaaaatat tgactctgat
    18421 atagaaaaac tcgaatctaa aattgcaaca cttgatgaaa gtactgcaaa attttcaact
    18481 gattttacta aacttcaaga aattttagat gagaaatcta aactagaaaa ggaacttgaa
    18541 tacaaatatg aaagatggga atatttaaat aatctagctg atgaaatagc taataataag
    18601 tgatattaaa ataatcttaa gtttaataag ttttgcttta aatctatact ttataaatat
    18661 tttaaaggta gtgtctcaaa atgaactttt tagttttatg agacactctt ttttatgaga
    18721 aatcaaatat gttttcatca tttcaacaat acaaaagagg cttatctcta ttttgagaca
    18781 gcctctttca taattacctt ctaatttata tgctttaata tatctataat aattcttatt
    18841 atatctatat atccagtctt tcaatatagt gacaattaac ttcaatatga tttaaaaata
    18901 ctaacaacct ttcataaagt ggatgagatt cttctccata tttagcttct aggttcttgc
    18961 ctatttctct aacagtcctt tgaccatcaa tttgtaaaaa aacaaaactg gaatattcat
    19021 ctagttctat ttttttgtat ttaggtattc tagcttttaa ctttctaaaa aacttttgaa
    19081 ttttatggtc ctgtttttca agtatagtaa caacactatt ttcagctact tcatattcaa
    19141 gtccatcagt aattttaaat acaatatcta aaacatcatt actcttgctc attatttttt
    19201 actttagata aaacaatagg taatgttgta agcacaacta aaactactaa taaagcaatt
    19261 gccattgaat ttgttgcagc aaatccactt ggtacctttg gagttacaac tccagttact
    19321 tgtaatatta tacctattaa accaatgata gaaccaccag caacaagacc agaagataaa
    19381 cttataccat tagaaacttt aacttctttt tctttttcag ttttagatac taattcaaca
    19441 aataaacgaa ttaatgctcc aactaatatt atagaagttg ttgcaattgg taaatagaat
    19501 cctatagcta tagtcattat tggtaaattt aatgcatata gaactattgc cataaatact
    19561 ccaacaataa tcataaccta aggtaaacta cctgacataa taccagaagt taatgttgac
    19621 attaagtttg cttgtggtaa tgcaaattgt acattatcac cagttgctct aagttggtca
    19681 gaaagtaata aaattactcc tacaacaact ataacaccaa ctatacttgc aattgtaaag
    19741 taacgttgca tttcgttttt gctaccacca ataatataag ttactttttg agattgagta
    19801 taacctccag ctatagcaat agcaacaact ataaatgaac caaataaaag taatgattta
    19861 ttagcttcta aatcagtcca tcccattata acaaacacta atgttacaat aactagagaa
    19921 gctatagtca taccagaaac tggaagattt gatgttccaa ttgttcctgt taaacgacca
    19981 gctactatga caaataataa agataataaa agagatatga tagctccaat aattgccata
    20041 acaatgttac cagaaattaa gaatgctgct aaaaatccaa taactactcc acctaataaa
    20101 agtatcattt gtatagatga accttcttct ccttctccag cacttgattt agctttaagt
    20161 gtttctttta tagaagcgat tatagttggt ataagtttta ttgcaccaat aatacctcca
    20221 caaagcatca taccagcacc tatatatttt acataactac tagatattgc tccgacatcc
    20281 atttggttaa gaggcattgc aggattattc cataccatag ctccatcttt agccatatct
    20341 gtaaagtatc ctattaaagg tgctatacca aagtttgata aaatacttcc tgcaaacatt
    20401 gttaaagaaa cttcaagccc tactataaat ccaattccta aaagtagagg atttacttca
    20461 atatcaaatt tccatttgta gaatttgctt cctacaagac tcattacatt gtttgctaca
    20521 tttaagaatg aaccagttaa tacagtaata aatccactta ttacaaatcc aattcccatg
    20581 tacttaattg aatctccacc agcctctgaa gcaacaagtg tctcagatat agccattgat
    20641 tctggataca taagtttacc atgttcttca actattagat agttgtgaac tatagcagca
    20701 attcctatac caaataaaac tccaccaact ccaacagcta agccttcaaa gaatgtaatt
    20761 tggcttccaa ttaatataac tgctggtaat acgaaaataa atccacttgc aacagattct
    20821 ccaccacttg acataccttg gattaagttt ttaccaagaa taccctttga acgagcaaat
    20881 gctccaacaa aagcagaacc tattatagct cctggaatac ctgcggcaac tgtaagaccg
    20941 gctttcattc cagagtaagt tgtagatgcg gcaaaaatgg cagctaaaat aataccgata
    21001 atcagtacag ctacatttcc accggttctg gacttatctg tgatatatgg aacgtaatct
    21061 tttccactaa cctcaccata agcaccctta ggtaattttt tgttcataaa attttcaccc
    21121 cttttcaatt tgtatatatt ataacatata tacatataaa acttaacttt ttattatttt
    21181 acaaatagcg agtcaaaact actaaaattt aaccctatat tattaatttc tacttttaga
    21241 tatttttatg ctaattttct ttttattttt caattctact aaaaactatt aagatataaa
    21301 ataaaaaatt ttttaatgta aaattaattt tgtaaaaaaa atgctttaaa acacggaaaa
    21361 gtataaaaaa tacaataatc attcttataa ataaattttc accatagtaa atatatacag
    21421 aaaattcttt tttttacatc aattgatttt ctcagaaaaa taggtgtcat aaagaaatgt
    21481 atggaatcac tttacaacac ctgtcataat aaaaaatcac tctggtagtg cttttttatt
    21541 tacttttcct attggtgtaa ctggtatttt atctatcctc attattattg ttggaatcat
    21601 atatggaggt agatgctcat ttaaatattc tctaatggtt ctttcattta tcttaccact
    21661 atcttcctca tcaattacat aatatgcaca tatatacata tccccgtcat catttgttct
    21721 cgatatacaa acaacacttt taatttctgt aatattattt attatatttt caatctcata
    21781 tagctctatc ctaaactcat caatttttac ttgattgtcc atccttccaa tataatctaa
    21841 atttccatca tctaaccatc ttactaaatc accagttcta tacattaact tattatgttc
    21901 acaagttttg taaggattct ctacaaatac ttgctctgtt agcccttttt tatttaaata
    21961 tcctcttgat atttgaatgc ctgatagaca tagctctcct ggtgctccaa ttggacatag
    22021 tttgttcttt ttatctaata catatgcata agtattaaat ataggttttc ctattggtat
    22081 ttttccatat tctctgtcca catgaaaaga agtcgataca acagtaaatt cggttggtcc
    22141 atactcatta tatagttcat aattacgctt tctatatcct tttaatcttt ctcctccagt
    22201 ctgtacaact ctaagtgaat tattattgca attttgtata aataaccttg caaatgctgt
    22261 tggcaatgct agtatagtta tgtcattttc ctcacagtat tcatttactg tatattcatc
    22321 aaatttagct tcttcaggca taatatctat tgatgcacct acaagcaaat aaggaaatag
    22381 ttgtttcatt acagcatcaa aactgaaact taagtatata ccacatatat cattttctgt
    22441 agcgcttata gattttacgc tataataaca catatttact aaactcttat gttctatagc
    22501 tatggtcttt ggcctaccag ttgaccctga agtagatatc gtatatgcac aatttgatga
    22561 tgttattttt tcagttaatt catatccaag cttaaacatt tcttcatcat ttatatcgag
    22621 tactatggta ttctcattta caaccttact tttgagttca tctgtagtta tcactacttt
    22681 tgcattacta tcttcaagaa ggtaattcaa tctttcttct ggattactcg tgtctattgg
    22741 aaaaaatgct ccccctgatt tcataatccc tattgctgta ataattatgt taatatctct
    22801 tggtaacatt acagctacta tgtcttcact ttccactcct atatgattta aataacctgc
    22861 aagtttatca gttacctcat ccaattcttt atatgttaac tttctatttt catccctagc
    22921 agctatatta ctaggtgtta ccttaacttg ctccctaaat aaatcaacat aacttttatc
    22981 atagggtact tcatattgat tattattaaa gtcttccaat aatacttttt cttcttcctt
    23041 acatacaaat tctaaatctt ctattaaaat atcattatct tctattattt gctctattat
    23101 ataatcaaat tgatttaaaa ttcttctaat agtttctctt ttatatatag atggtttata
    23161 ctttattttt attttaagtg ccctcttagt atatactatt acagataaat catatccttt
    23221 tttttctatg tcataatcat atgataaatc aaaactttta gctataaata ttgtgtttat
    23281 aagcttagta tttagatgat ttttattctc tatatctgat aacaaatagt atccatactc
    23341 taaagacctg ctccactgcc tttttagctt ccttacaaca tctataaatt tttcactttg
    23401 tctaactctt actcttattg gaattatatt cattgtttta ccaaaaacta catcatcttc
    23461 atatatatac ttttgaagta taagaccata tatagtttct atgatagagt ctatgctaat
    23521 attgttcact ttagaatatt gaattaacct ttcatgtttc tcaatattca tcttaaaaac
    23581 ctcatctact acttcatcag aacaatcttt ataaaaaaaa tcatttggaa tttttgctat
    23641 attcgtataa tcatctaaca aatccatcca ataattcata gctcgttcta aattaacttc
    23701 atacatatca aaattccccc ttactactaa gtctatagaa aaaattcttt tggaatttta
    23761 ttttcacaat atataaatat attaataata catatgcaag ctctaaaaac atgagcttgc
    23821 ataaaattac acttattatg actactaaat tcgtaatatt tacaatgttt aaaatatatt
    23881 ataacacata tatgatttta tttttctaca tttatataat atataaatta caaatagtta
    23941 tttaactaat atataacaat accttttgga atatgatata ttatattaat taaattttta
    24001 taagataagt tatacttata ggagggaacc atataaatga atatttatgc tcataggggg
    24061 tttagtggaa agtatccaga aaatactatt ctagctttta aaaaatgttt gtatatggat
    24121 atatatggaa tagaacttga tgtccacaga actaaggatg gaaaaattgt agttattcat
    24181 gatgaaaagg ttgatagaac ttttaatgga catggttttg taaaagactt tactttaaga
    24241 aaattaaaaa ctctaaactc atcttttgaa ggatatcaaa acaataaaga atgtaaaatt
    24301 ccaactttag aagaagtatt aattctaatt tcacctacag accttatttt aaatatagaa
    24361 ctaaaaactg acaaaataaa ctatcccaat atagaaaaag acgttttaga gcttatttta
    24421 aagtataata tgaaaaatag agttcttata tctagtttca acagcaatag cttaaaaaac
    24481 tttcataaat tagaccctag tgtaaaaaca ggattattgt gttatttacc tataaacaat
    24541 gtagtcaatt ttgctaaatt tctgggtaat agttaccttc atccacctct agttttagta
    24601 aatgaatctc taattgaact ttgtcacaaa aatctacttg gtgtcaatgt atatactgta
    24661 aatgaagagg atgatatact acactgtcta aaactcaatg tagatggtat ttttactaac
    24721 tatccagata ttgcttcaaa tcttttacac tcaaaacaat acagctaatt atacaatagt
    24781 ttgtactcct tgacttttat ataattaata tgtacaattt tattaaattt atcttggagg
    24841 tataactatg gataacttat taaatgaact tgaagcttta aagagtaatt tagataatct
    24901 accaatagaa aaaatagaaa attatgattt gagtaaaact gctttattta taattgatgt
    24961 taataatggc tttgcaagac aaggtgcatt atactctcct agagtagagt ctttaataaa
    25021 accaattgaa atgtttacaa aaaaaatatc aaacaaatta aatagagtaa tagcatttac
    25081 tgattctcat actcctaaat caatagaact tttgagttat cctgttcact gtttggaaaa
    25141 tgatgtagaa agtgaattgg ttgatgaact taagtcgata gaaaacctac aaattcttcc
    25201 taaaaattct actaatggat tttttgcatt agaaaatttg gattttgata atatagataa
    25261 tataattata gttggcgatt gcacagatat atgtatatat caatttgcaa taactctaaa
    25321 atcatatttt aatcaacata atattgaaaa aaatatagtt gtacctatga atttagtaga
    25381 tacttatgat attcctaaca ttcaccctgc tgagatttta aacttagtat ttttcaacag
    25441 tatgattcaa aatggagtta atgtattaaa agagattcgt taagcctcta atactttaca
    25501 tcccatataa tacaattatc agatatttat ttttaataaa atttctaata gaaaaacaca
    25561 gttttagtga gaagattaca atttaaaaca ctatctatta tgactaatct tcacaatata
    25621 aaaaatcgca gtttagatat tccttataca aatttataag gaataataaa ttgcgatttt
    25681 tatttttaag tagtacaatt aattgatact acttcagtat ttaaattcat ttcttaataa
    25741 tcatacttat tcgtagtttc gcacattact acctttattt ttttattaaa catattctta
    25801 tattctaata aaaactcatt tagttctgaa tccataagat ttatttttct atcactacaa
    25861 agcattatct tttcttggtc gattattaca ttaatatcat ttaagtcatt ttttataaat
    25921 gttgttatac aactctttgg ttggattttt tctccatatt tctcataaaa tcctgcactc
    25981 ttcttaaatg actctaaatc ttctgtagat actttgctgg aagtattatt actcataaaa
    26041 cctgctgtag aagggtcgat tccaaagttt ctaagttgtt tttctacttc ttcagtgtcc
    26101 ataccatatc tctccataaa ttgcttttgt attttcataa atttttcttg agatatgttg
    26161 ttatctctca tataatcgaa tatttttctt gaaaactcag ccatggacat ctttccatcc
    26221 ataacagaaa aatataagtt atatatgtat tgctcaaatt tatctacatc agaatcttta
    26281 actttgttct ttagttcgtt aaagtctatt attctatcat cagacatttt tcatcctcct
    26341 agctaaattt ttacttgtat aagattatac catatttcta ttatatttat atacacacta
    26401 tttttttaat ttaacgattt tttctgtagc atctaattcg cacattctgc ccaaaggaat
    26461 agttatcatt gggatacaat gtcctgactg aagattatat atagaaggtt tattgacctt
    26521 atttgcaaat tctattagta attccatcaa atcattttct tcaatacaat ccttaaaatc
    26581 tccaaaaatt ataccattac attcctcaag ttttcctgaa gaatatagtt gtgttaacat
    26641 tctatccagt ttatattgag gttctccaat ttcctcaata aacaaaattt tatcttttgc
    26701 atctatttca tattttgttc ccattgtggc aattattaag gataaatttc ctcctattat
    26761 tattccctct gctttacctt cacatacagt ataaatcttt tcttcttttg gattttctaa
    26821 atataagtca tctttaaatt ctaaagcatt taccaatgat ttataggtaa atttatccca
    26881 tttacctaca tttgctgcca ttattccatg atatggtaaa agtccacaat ttttataaaa
    26941 agctaaattt aaacctgtta tatcagaaaa acctataaat ggttttggat tttgctttat
    27001 tatatcataa tttattttat ccaatattct tgttgttcca taacctcctc ttaagcacat
    27061 aattatatct acatctttat ctaaaaacat atcttctata tcccttgctc taatatcatc
    27121 attaccagct aaataacctt tataatttaa actacaactt tcagaaaact taacttcgta
    27181 accataactt tctaaattaa actttatttc ctccaaactt gtatttctta atggcccaga
    27241 tggcgcaatt attcctaaca tttaaacacc tcttcttata aaatgatata ttcttctcca
    27301 tactaaatat ctctaatata attataagat attttatttg tacttgatac ataataatga
    27361 tttacataaa ataatataat taatgaagaa aaataaattt ttaatatagt taggatgtgt
    27421 tttatgctta atataagaac tctttgtcat gagataaatg attggattat aaatataaga
    27481 agagatttac ataagactcc agaacttgga ttagaagaat ttcaaactaa gaaaaaaatt
    27541 attaaatact taaatgaaat aggtataaat tatattgaat ataagaatca tacagggata
    27601 actgcataca ttaacgtgag tccaaacttt gaaacagttg ctataagagc tgatatagat
    27661 gccttaccta taacagaaga acttaattat tcttataaat ctattaatat tggtaaaatg
    27721 catgcatgtg gtcatgatgc acacactgct attttactgg gtacttgtaa tatactattt
    27781 aaattaaaga attacttaaa tgtaaatgta aaattctttt ttcaacctgc cgaggaaact
    27841 attggtgggg ctcaacttat gatagaagat ggatgtcttg aaaacccaaa tgtaaaatat
    27901 atatttggac tccatgtaaa tcccaatatc aacaaaaatc taattgaatt aaaatacaac
    27961 actctaaatg cttccaccga tacacttcaa ttaactgtac atggttcaaa atgtcatgga
    28021 gcttatccac atcaaggtat tgatgctatt gttatatctg ctcatattat tacagctcta
    28081 cagacaatcg ttagtcgaaa cacaaatcca actgattctg tggttatttc tctaggaaag
    28141 attgaaggtg gaatcaagga aaatatagtt tgtgacaaag tggttataag gggtactttg
    28201 agaaccttga ctcctgaaac tagagagttt tcaaaaaaac gaattagaga aatttgcgat
    28261 tttacttgta aaacatttgg aggaagtatt tctgttgaaa ttgaggaagg ttatccagct
    28321 cttatcaatt caaaccatct agtagattac gtcaagcaaa atgctgtaga attgtttgga
    28381 gaagaaaata ttatccttaa agactcgccc actcttgggg ctgaagactt ttcgtatttt
    28441 ctaagacact gtgaaggagc tttttaccac cttggttgtg caaatcgtga aaaaaacatt
    28501 acttcccctt tgcatacctc tacttttgat attgacgaag attgccttat tactggtgtc
    28561 atgctccatg taaaaaatgt attatcattc taactattaa tatttttatt tattatttta
    28621 tattgaccct cacatgatgt catgttatac cctaaaatta caaatgataa attaaatagt
    28681 tggaggtaat attatgaaag aaatattaat aaatcctata ggtaaaatat gtattcaagg
    28741 cgaagaggtc tttattaaat tagacaaaaa gtatgtacct gcattaaatg aactcgacga
    28801 tttcagtcat ttaaatgtat tttggtgggc tgatgggttt gataatcctg aactaagaag
    28861 tattttagaa accccaaaac cttataaaag tggaccagac gttataggaa tatttgcaac
    28921 aaggtcacct ataagaccca atccaatagc attgactgct gtacaaatta tcaatatcga
    28981 ccatgaaaat ggtataataa aaataccata tattgatgct aatgataata gtcctgttat
    29041 tgacttaaag ccatatactc caagcgttga taggattgaa aatccgtccg ttcctaaatg
    29101 gtgtagtcac tggcctaaga gtgtagaaaa atcaggagaa tttaattggg aaaatgaaat
    29161 tgaattttaa attacttttt tcttgatttc attaatttgt tttccacatt tattttattt
    29221 acacttacca agattttatg tcacatataa atataatatt aggctgtatt acataataca
    29281 gcctaatatt atataataaa tttctatttt tcccttaaat cattcacatt ctttctaagc
    29341 tacataagat ttttctatta tttctttttg agtttaattt agcattatgt tgaggaaaaa
    29401 acatttcatg cattttaata aattaaattt ttcttttatt ctacgatttt ataataatca
    29461 atttaactta aaaataatac ctaactattt taactatgtt aaactagtaa atgtaaccac
    29521 ttatatgtta caattttata taaacatcag atataaaaaa ctatataaat aaatgacaca
    29581 tagtgttata ttttttaata ccaatttagt tatttttcag ttacagattt aataataatt
    29641 aatagtaaga cataatattt ttatgccctt tattgattat gtattttctg ttatctgtta
    29701 ttatcatcaa taataaacat aagggggtat atattatgaa attgtattta agtgctgata
    29761 tagaaggtac ttgtggtatt gtaaattggg atgaaacaaa acttgaatgt gaattttcac
    29821 aacactatag aacacaaatg agtaaagaga taacagcagc atgtgatgga gctactcaat
    29881 ctggtgtaca tgaaatactt gttaaagatg cacatgacag tggtagaaat attaatccaa
    29941 atattttacc tgaaaacgtc aaaatactta gaggatggac caaagaccca ctagttatga
    30001 tggctggaat tgatgaaagc tttgatgcat gtatattcac tggctatcac tctggagcta
    30061 cttgtaatgg taatccactt tctcatacta tggatattga ttatgactat tttaaaataa
    30121 atgatgaaat agcatctgaa tttactataa atgcttatat tgctgcatat tataatgttc
    30181 ctgtagcatt tttaagtgga gatgaaatgc tttgtgagag tgcaaaaaaa ctaaatccaa
    30241 atatagtcac tgtttctgtg tcaaaaggaa ttggaaatgg ttcaatttca atccatccaa
    30301 accttgcact aaaaaaaatt gaaaaaggtg tcaaaaaagc tttatctgga gatttatcta
    30361 gacacttaat aaaattgcca gataaattta agatagaaat aaaatttaga gaacattata
    30421 aagcttttaa ggcctctttt tatccaaata tgaaaaaaat agattctcaa acagtactat
    30481 ttgaaacaga agactattat gaatttttaa gaatgttatt atttatataa atttcatatc
    30541 ataaattaag gagttgatta agataagtaa taaaagaagg attcctttag gcgaatttat
    30601 ttctgtattt ttattttttg ctgttttttt tggtataact ttttgtattt tcacggttat
    30661 aggaattggc ttcttatcat tcttaggatt tgaatataaa tctcttggag ctgtattaat
    30721 tttcttttta atatattttt gtataaccac tccaattgat tttctatgca ctactatttt
    30781 agatatattc agatatgtaa acaaattacc atactcaata tataaacttt gcgaatttat
    30841 aattgatttt atactaactt ttctagctat gaacataatt gataccttta tggattcagt
    30901 aacgattcct ttaagtacag aaatcttatt cgctttactt tcttatcttt tatcagaatg
    30961 tatggatttt tttgataggg ataagaaaaa accttaataa aaaagataga ttccttaata
    31021 gaacacatat tttcgtattt ctattattta atctatcttt attttattta ataaattttt
    31081 attaattaaa atatagtttc ttctatctcc ttagtcattt gcttagcact atcaaaaaat
    31141 tcttctatat acactacttc atcactgacc ctagaatatt ctgctgcaaa tgccattaca
    31201 tgactttgta tagcttcttt tgctgctact ctaccctttt ctagttcttt atttgaaact
    31261 aatttaataa attcagctat aagatttcta tcatattcct ctaccatatt ctgttgattt
    31321 gatggattca taactatttc ttcgtttttt ccaaattctt taattcttat ctcattttta
    31381 tttaaatccc caccaacttc accatgacta aacattaact ttatagttct tccattttct
    31441 ttagtaaatg cacataaatt aaaagtagcc gtcactccat tttcaaactg taatatattt
    31501 accatattgt ctacaacatt attatcacat ctgtaaacac atcttccata tggacttgtc
    31561 ttaagtatat ttaatagatt ctcttcagtt ggatttatgt gaacagctct atttatactt
    31621 ctatcttttt ctaaataaat tctctttgct gaatatggac attttttttc aactaaacac
    31681 tgaagacaat tttgtgccat ctctccacta gcattttggt tattaagatg ctttaagctt
    31741 ccaaatgcag atattttttt gcatctactt cctactaaat ataacaaaat atccatgtca
    31801 tgacaactct ttgctaaaat taaagggctg gtttcattgc tatttctcca attccctcta
    31861 gtaaagctat gtgcaaaatg ccaatatcct atattttcat tatattgtat actaactagc
    31921 tctcctaatt ttttgctttc tacaatttct tttaatttat tataaaatgg agaatatctc
    31981 agtacatggc aaatcataaa aatcttatct ttatacttat cacacaagtc atctatatgt
    32041 accaaaccat ctaaactatt agacattggc ttttctaata gtacatgata acctttttca
    32101 agagctagtt ttgctacatc ataatgtcta tcatcatttg tagctattat tactgcatct
    32161 gccatcttgt catgtttaaa aaagtcttct aaagtttcaa atacattttt actatctagg
    32221 ttatattttt gtgtaaatag ttctcgtctt ccttttttag gttctgctac agcaactatt
    32281 tcacatacat cagaattttc ataaatatat ggagcatatg catacgttcc tctattacct
    32341 gctccaatca cagcaacttt cactttttcc atactttaat ttatcccctt tatattattt
    32401 atactactct attatagtct atttttacag acatttggat atttttaata aaagaaacag
    32461 cagttataat ttttcaattt taactgctgt tataagttaa tataccaaac atttttaatt
    32521 aaattttctt taattttaat acaaatactt aaatattcaa tacaaattat aaaaacactt
    32581 ttatctagtt tacttcttct tttctttatc taatttatct aacttcttat tgtataaaaa
    32641 catataaaat gctgccgaaa atactattaa atatccaaca acacttaaca tatctggata
    32701 gacattgaat aagaatatac ttaaaattgc tgaaaagatt atattactat agtcaaatat
    32761 agagatttcc ttagcaggtg catatttata tgctagagtt attccaaatt gacctagact
    32821 tgcaaatact ccacctagta atagatatat aagttgcata agagtcattg gttcatatac
    32881 tgcaaaagca attggcccta cagtaactaa tgaaaaaact gaaaagaaaa atacaattgt
    32941 atagtaatct tctctatctc caagaactct taaacaagta tatgccattg ctgcaaatac
    33001 agctcctgca attcctccaa gatatggaat tacttctaca ctaaatgttg gttttattat
    33061 gaataaagct cctataaatg caattataat agctcctatc tgctttacat ttattttttc
    33121 ttttagagca attgcacaaa atattactac aaggaaggga ctcattttat ttagcatatt
    33181 agcatctgaa agcatcaact tgtcaattgc atagtagtta aatataactc ctagagttcc
    33241 aaatattgac ctatataaaa gtacttttaa attttctttt ttaccagtta gacttccttt
    33301 atgttttatg ataagccaaa aagctattat agctgatacc agatttctaa agaacacttt
    33361 ttgaaaactt ggtaaatctc cagctagctt tacgaatgca gacatcattg caaagccaag
    33421 cgctgatgct attataaaca ttataccttt tattcgattt gatttgattg tgctactcat
    33481 acgtacctct tttctatata aatgtataaa gccatattaa ttaaaaactt agcttataca
    33541 ttaaataata attatctaaa tattccaatt tatactataa ttaaaagtgt aaactatgtc
    33601 aagtaactaa taaatctttt caattaataa caataataat tatagctaaa aagttatatg
    33661 tttttatgga ttattatcag aatatataat ataattttat atagtataga ctttttttaa
    33721 tttattattt agatttttaa tagatttttt aactatggag gtatttaaaa tatggaaata
    33781 aagagatatg aaggaactgg aagaatgagt agagctgtag ttcataacaa tacagtttat
    33841 ttatgtggac aaactcatgc tgaaggagga gtaattgaac aaacaactga agttttagct
    33901 aaaatagaag atttattaaa caaatatggt tcagataagc aacatttgct atctgttact
    33961 atttatttaa gagatatgaa agactttgaa gctatgaact ctgtttggga tgcttgggtt
    34021 gaaaaaggat ttgaacctgc tagagcttgt gttgaagcta gacttgctag agagcatttg
    34081 ttagttgaaa tgagcgttgt tgcagctaca aaataatcaa tttagtttat aggaggctat
    34141 ctcaaaacag agagataagc ctctttttca ttgttgaaat gatgaaaata catttgattt
    34201 tgtataaaag aaagtgtctc acgaactaaa aaattcattt tgagacacct cctcactatt
    34261 taatctatat aaatttactt attctctatt ggcaatatca atttagatgg atatttacct
    34321 ccatgataaa tcgtattctt tgcttctata tattcaatac tattatatcc ctctgtcgtg
    34381 ttgctatttt ggaaaataaa gtttttagca ctagacgtta tatctagtct aattttatga
    34441 ccaactttaa acgtgtttga tatttttgaa gttataatcg taaacttata aatctctcct
    34501 tcttccataa actctgactt ataaaaacta tttctaaatc tagcactaag tataccatca
    34561 gctaatttaa ttgaatttcc atctaaatcc acgtccataa tttttataac ccagtcagta
    34621 tctttggcag aacttgatgc aaaaaactct aactttatat cacctgttac agtaaattct
    34681 tcactaaaag catctgatgt ataacacaac atatcacttc ttttttctaa atctttgtag
    34741 ttatttggaa ctccaacttc attctctgac atatcaatta gttgtactga tgggtctttt
    34801 ggattatata tataactatc atacttttct tctaaatcat tatcaaatac taatctacca
    34861 tttcctaaag atgtgttagc atttccatca cttattagat acatactttt atctatctta
    34921 tttattattg gccaattttc ttctgtcttc cacttattag aacctacaga gtaatactct
    34981 actggagcag tcgtatctat gttattttct atacctttta agtatttatc aaaccataat
    35041 agataattat aatccaaatc atatcttaat gaactatttc ctaaagaaat accatttata
    35101 tctcttaaag tatttgaatt atgcatccat ggacctagaa tagcctttct ctttcctttt
    35161 tcatagtcct ttataacatc taaggcctct gtagttccca tactattatc atcataccac
    35221 ccagatacaa ccaatgcagg tacatttatt ttatcttttt gtaaatgcca atccatcaaa
    35281 tcccaatact catctttttc tactctcttt aaccattctt ccagaaattc aattctatat
    35341 ccaagagctt caacaggtat attttctatt ggtcgtatgt ttaaaacatc atcccaatca
    35401 tctcttacca ttttgcttct atcaacttta tttcttgata ccataaatgc ccatgcaagc
    35461 ataccagata caaaagctcc tccttttctt ggtatatcaa taaaagggct tcctgatgtt
    35521 actatactaa ctaaagcttt aagatgctta ttgcctgaag atgcagctgc ccattggaca
    35581 taaccaagat atgatgctcc aagcattcca actattccac ttgaccattc ctgtgatact
    35641 atccaattta tggtactatc tccatcttcc ctctcatgaa tcataggttc ccacttacct
    35701 tctgattcat ttcttcccct aacatcttgt attacaacag catatcctct ttgtacatat
    35761 ttataatata tttctttatc attttctttt ccatatggag ttctcataag aattgttggt
    35821 gcttttttgg tagaatctac aaaatcaggg agatatacat ctgtagaaag ttttatacca
    35881 tctttcatat taatcatata atttccacca aatcttatag aatatatctc ttcattttta
    35941 tgagtttttt cccattcttt taatacagta tactcttcat atccatccat aattaatata
    36001 gtacaagttt ctctggataa acagataaaa cctactattt tattatctac aataattata
    36061 tctagtggga actttttatt tctttgaacc catatatatt cattaagttt agaatgcgtt
    36121 tctcctaagt tatttataac tgtgtcttta tctgtgttta ctaagctttt agtatataca
    36181 tcaaagttat taaataaaga ctttaaatct atttttgtaa gatttaaata atatgtattt
    36241 tcttctttgc ttattgtttt taaactttct attttatttg taaaaggatt caacttttca
    36301 attaataaat ctccatcaaa gattacattt ccactgtata gtccagatat gtataattta
    36361 aattttatca attaaactcc cccctataat cctagagaca tctttattgc atatgccact
    36421 gatatacctg cataatttcc taatactcca ccaattactc ccattacgac tgctacactt
    36481 acaagcgaat tccactttgc agaagcagct actaaagctg aagtaggacc atcagcaatt
    36541 gctcctacta tagaaagtat tacatattga tactttatct ttaaaagtct agttatgcct
    36601 aaatggaaaa caaatgaagc aaaaattatg ctaaaacagt aaagtgttat agtaaaagtt
    36661 gaacctaaaa actcttttat atctactgaa aaacctattg tacataaaaa gaataatgca
    36721 acaaataatc ctaaatctaa atttcccttt agtttcttta ctggctttaa ttgagcaatt
    36781 ataattgaaa ttgttgtaac taaaagtatt cttgctgcac tactaaaact tgaattgaaa
    36841 tatccagcaa gtattgttga aacttctgta acaacaaaac ctatagccaa catccaagct
    36901 atatctttaa tactccattc ttttgactcc ataaattctt cattttgaca atcttctaat
    36961 tctgattctt ctacatgata tggccaaagt ttcttaaact tctttgaatt ttttaatatt
    37021 gctggtagag caaacataaa tatcaatgtt ggtactccaa ttacatagtc tgctgcattt
    37081 gctgctgcaa gagtttgtct acttacatta agacctgttc caatagctgt aagattagca
    37141 cttccaccag tatatgtacc tacaaacatt ccagcaacct tccaaccttc tgatattttt
    37201 tctgcaaata ctaatccaaa taaaaatgcc atgatactta cagttaatac agctacaaaa
    37261 attgcaatta aaggttctct tgataatttt gtcatttctt ttaagtcaac actcatcaac
    37321 attatagtca tagaaactgg aatagcatat gttgaaatag ttccatataa ctcagtactt
    37381 actggaacta cttttaagtt tgaaagtatt attcccatta tgattattgt aagtgctggt
    37441 cctaagcttt taatggcttt gtatctttgt aagtaaaaac ccaatgcaat cattgatgtc
    37501 attacagcaa gtatactacc tggatttgaa aaaagtgtat tcatatttaa cctccaaatt
    37561 tatcataagt ttacttctat tcctaaacct ggtttattga caagattcat aatatctcca
    37621 tccattacaa atcctccaga tatatctttt gattcttcac aaaacataaa actatcaagg
    37681 tcagcttctg ttatgttctt tttagatgct attaaatttg ctgctgctgt tataccaatt
    37741 ctcgtttcca gcatacatcc taacatacaa tttactccac ttgcctcagc tatgttgttg
    37801 atttttatag caggatatat tccacttgat ttcatcagct taatattaaa tgtatcaact
    37861 gcattctttt ttatagcctt aattgcatct attggtgaat gtaatgattc atctatcata
    37921 atttttgtgt tacttttatt tcttatgtaa gcagtaccat ctaaatccca atgtggaagt
    37981 gcttgttcaa ttgcatcaac attaaattct tctaactttt tgatagtatt tatactgcta
    38041 tttacgttcc atccttgatt tgcatcaatt ctaattctta tactctctcc aacggcttct
    38101 ctaattaact ttacagcttc aatatcgtct tcaggattta tacctgcttt aagcttcaat
    38161 atcctaaaac cttcttttac tctttctaaa gcttctactg ccattttttc tggcttatct
    38221 atacttatag taatatccgt ttggacttta ctatcaaatc ctccaagaac tttataaagg
    38281 ggtgcattca taatttttcc tttaatatca tataaagcta tgtcaatagc tgcttttgca
    38341 gaagtattac ctataataat tccatccatg attgtatgta tggtttcaat atctagtggg
    38401 tctttgccta ttaactcttt tttaaacata agtaatactg aaagaacatt atccaaaact
    38461 tcacctgtaa ctgctgcaag aggtgctgct tcgccaaatc cacaataccc ttcatcagtt
    38521 tcaattttta aaattatact ttctccatac tcaattactc caaatgaaac tactacaggt
    38581 ttttttaatt taattctaag cttttcaaat ttgatatctg ttatcttcat attaccctcc
    38641 ttattttttg aagttataat tcaattttta aaattttata ctttaaatta tattattact
    38701 tcaatatata tgtcaagata atttactgaa aatttactct tttccaaaat ataatgttat
    38761 aatcttaatt caattaatac tcttctatta aattttttta ttattatttt ctttatatta
    38821 atttaacaat aattcatttt catagacttt tatttggatt taattaaatt ttaattgtca
    38881 aaatctactg tgtattctta ttgccactac ttctatgttg tgctataatt actttgtttt
    38941 aagcgaatat tttatattaa ttttattatt tggaggttct tatgctaggt gaaaagatga
    39001 gaaatataag aaaaagcaag aaaaaaacat taagtgatgt ttccaaattg acagatttat
    39061 ctataagtta tatctctcaa atagaaagag atgctattga accatccttg tcttcattga
    39121 gaaaaatcgc tgaagtttta gacactcctt tatatatgtt tatggatgac aataatactg
    39181 atgatttagt cattagaaaa gaagatagag ttatgatgaa atttccaaag agtgaaatgt
    39241 tttacgagat agtatctcca atgcctacaa ctgagtttac accttcaatt ttatttgtag
    39301 agtttgaact taaaccagaa agtgaggatg ctaaagatta tatctatcat gcatcagaag
    39361 aaattatggt ggtaacgagt ggtgtggttg atatttgtat gggtgaaaag gtagttagat
    39421 taaatccagg tgactcaaca tttataaaag ctaatgtacc acataaaatc atcaatccaa
    39481 gtaaagatac aatagctcgt ggatatggag ttatatcacc tccaatttgg ccaataaaat
    39541 ctaaataaac tcaacataac acacctactt tttgtagata atataataaa tttaaatatt
    39601 gcttttattt taaaattgaa gtatttattt aaatttaaaa tatttactca aactaaaaaa
    39661 atagctattt gactaatcta aaccatctta attatggtaa atagtaaata gctatttgta
    39721 agttatatta taaattataa taaaaattgt atttgttaaa attaaactgc tatatcattt
    39781 aatacttttg cctttacaac tcttatattt ttcatactct tgtagatatc ttgaatctta
    39841 tcttcttgct ctctcaatag tctatgtgct tcatatatat ctacaagttc aaattttact
    39901 acatcatttg gctttgcttg tgctaactta tacaaatcta cacttataac gttccctatc
    39961 ttagtatagc caccactagt ctgtctatct gataacatta taatcggttt tccatgacca
    40021 ggtacttgta tagctccata agaaatacca tcagatataa tatctgctcc attaaggtgc
    40081 tttatactct ctccatctag tctacaaccc attctatcta tttcattcgt aactttgtat
    40141 ttatttgata aaaatttctc tacttcaccg ttagaaaaag catcaaattg aggacctttt
    40201 acaattctta gtacgatttc tgaactataa gttggaatat attttgaatt taatttttta
    40261 tttattgtaa aatctttttc ctgaataaaa gtatttatat aatctccttt tttaagtgct
    40321 ctaccttcaa atccgccaat tttagctctt gtataagttg acttacttcc cattgcaagt
    40381 ggaacatcta ttccaccagc tattgacaca taggctctag cacctgattt cacacctcta
    40441 aatgataata catcacctgg atttatttga tatgacctcc agttttgaat ttcttttcca
    40501 tttattttag cccctaaatc tcccccagtt actgctattt gcgtatattc atcaaaggta
    40561 attgtaggac ctaacattaa aacttctaaa gaagcctcat cttcagaatt tcctactaat
    40621 atatttccta ctctatgtgc atactcatcc attgctccac atccagatac accatattga
    40681 ccatagccaa ctctacctct gtcttgtatt aatgtttgga aacctcctaa ttcaactttg
    40741 aatcccatat ataccactcc ctgtactata acgatattta aatacttaag ttattttttt
    40801 cgatttctat aaattcatct aatgttattg gaacaaattt tataaagtct ccagctctaa
    40861 gcaaaatctg ttcttctcta ttttcatcat ataattttaa aggtgtccta ccaattattt
    40921 gccatccacc aggactatca ataggatata caccagtctg ggaacctgct attccaacac
    40981 tcccaccata aattttagtc cttggcactt ctaatctagg tgtagctatt ctttcatcca
    41041 taccacctag atatggaaat ccaggagtaa accctagcat atatatcaag tactctctgc
    41101 ttgtgtgtat ttttataact tcatctacag tgagattatt gtagcttgca acgtttttaa
    41161 tatctatacc aaaaacctca tcataacata ctggaatctc atgtatttta ggttttggta
    41221 atactatact ttccaaatta tcttctattt tttttaaatt ctcaatcaaa ctatcaaaat
    41281 ctatttctaa tggattatag cttatcataa gtgacctata tgttggtacc atttctgtta
    41341 caataccttt aagattcgat atttctattg ctctcataaa tgaaattact tttttgttta
    41401 tatcttctga tatctcattt ccaaattcag caaccactgc cttatcccct gatatcaagt
    41461 atctagtttc cataaatgtc acctcttcta aattaagcaa ataaagcacc taggctgcta
    41521 agagaagtta ttcctgtata tgcagatatt aaaactacta ttaatccaaa tattaaaagc
    41581 catgtaggat gcttgtaatc tccaacaata tcttttcttt tagatgctat aagcataatt
    41641 cctaatgtga ttggaagtat caatccattt aaagctcctg ctaaaattaa taaagtagct
    41701 ggttttccta taaatgccat tataagtgtt gatattgcta taaatgctat tataaaatat
    41761 ttttcatatt tatctataaa aggatttagt gtctttaaga aagaaactga tgtataggca
    41821 gctcctataa ctgatgtaat tgcagcagac cataatacaa gcccaaagaa tttatatcct
    41881 attgctcctg cactaaattt aaaagctgaa gcagctggat tttctgggtc aagttgaaga
    41941 ccttttgaaa ctactgccag tattgctaaa aataaaagaa ctctcatcat tgtggcaact
    42001 aatataccca aaagagaaga tttagttatt tcttttatat tttcttctcc tgttattcca
    42061 ccatctatta atctatgtcc tccagcaaaa gttatataac ctccaacact tcctccaagt
    42121 agagttatta ttgggaatat caatcctttt ggattttctg gttttaccat tcttgatact
    42181 gcctctccaa caggaggatg atttgatatt gctacatatc caactataat tatcattcct
    42241 aatgctaaaa atttagttat cttatccact agagaatttg aattttttga cataaataca
    42301 aatatggcta ttaatccact taatacagtt cctaatgtca tattcatatt aaacattaca
    42361 ttcataccaa gtgcagctcc accaacattt cctatattaa aagctaatcc tccaagagct
    42421 actaaaaaag ctactaaata gcctaatcca ggtattattt tatttgctat atcctgacct
    42481 ctaagtcctg atacaccaat tactctccat acatttactt gagcccctat aaaaaggatt
    42541 gttgtaatta aaattacaaa tgaaaaattc ggtccaaaat cttgggtaaa ttgtgcagtc
    42601 tgagttaaaa accctggtcc aattgctgat gttgccatta taaatgcagc ccctataagt
    42661 gctccgacat cttttttatt tttagtttta tctgtaatat tttttgtact catattttat
    42721 ctccccctca tgttatcagt cttatactat gttctctgat gaacaaactt ctatgttttc
    42781 taatggacaa acttctatac tttctaattc aaaacgcttt cttatttctt tgacaaactc
    42841 tattgctttt ggattgtccc catgtacaca tatagaatct gctttgatat gtataacttc
    42901 acctgttaaa gtttctacag ttccttcttt taccatccta acaaccctat ctattgcatg
    42961 ttttgtatca tgtataactg ctccttctac acttcttgga accaaaaaac cattattatc
    43021 ataagctcta tctgcaaata cttcatttgc aaacctaagt ccaatttctt tagcagaatt
    43081 tatcatttca ctattatata gccccaatag tataatatct ttatcgactt catatatagc
    43141 ttcacaaatc cccatagcta actctttatc tttagctgcc atattgtata atgctccatg
    43201 tggttttaca tgttgtatat tacatccatt tgaacttgca aatgccatta aagcacctaa
    43261 ttgatatttt gtataatctt tagcttcctg ctttgttatt ttcatctcac gtcttccaaa
    43321 tcctattaaa tctgggaaac ctggatgtcc gcctattttc actccatttt ttttagctag
    43381 ctgtactgtt ttttccatat gactagggtc acctgcatga aacccacaag ctatattggc
    43441 cgatgaaata tattttaaaa cttcttcatc taaaccaatc ttatacgttc caaaactttc
    43501 tcctaaatca ctatttaaat ctactttata caatttatga cccctccttg ctaacatttt
    43561 gatagaataa gtagttttaa tttttaaatt ttgtttattt tatatattgc atgaaatatt
    43621 ttatcacttg tattcaattt tatttttgca actattctat tgcatttaat taatataatt
    43681 ttaccattta aggaatattt ttgcaattat tttaattgaa cattcatttg tatttctttt
    43741 tcaaaaaatc tttttaccat tttttagtta ataattaatt attttcactt aaaataaggg
    43801 ccttaacctt catttttaaa gtatttttca tttttaatca ctttatatgc aagacagaat
    43861 catttttctt cattcatttg tttctttcat ctatataatt atcattcttt gtaagtaaaa
    43921 tatctttata tttttataat taattcttta tatagtttta agtataataa aatcatgtat
    43981 actaaatgca tgttaaaata ttattttaaa acatgcacaa tatttgtaca tattgtagac
    44041 atataaacct ataaattata caatagtatt gttaagatta tatatttttt taacataaat
    44101 tttgtattgg gggaaaaaca atggataaaa actatacgat gccaatatac caaaaaatag
    44161 cgttggatat tgcaaataaa atatacacgg gtgaaataca agaggattca gtactatttg
    44221 gacgctctgt tttggctggt aaatacaatg tatctccaga aacgataaga agagctgtca
    44281 aaattttaga ggacattggc gttgttaaaa gcataaaggg taaaggtgtt attgtactat
    44341 ctccagacaa agcttcttct tttataaaaa aatatagaga tattacaaat atatcatcat
    44401 ataaatcaac actttataat ttaatagata ctaaatctaa tttagaaaat gaaatattag
    44461 atactataaa taaaatttta gactattcca acagacttga aataatcaat cctttagtgc
    44521 ccgttcagtt caccataaat tctaattgca aatatattgg tcaaacagct gcacaaacta
    44581 aattttggca aaatacaggt gctacaatag ttgcaattaa aagaggtgaa gaacttataa
    44641 tatctcctgg accatatatt gaatttttag aaggagacat tctcttagta gttggtgacc
    44701 aacacattta caattctata ccaatgtttt tatatgaaaa cgaaaaataa attatataat
    44761 ttagtatgat tatataaaaa tgcaaaatta acaacaaaaa aagagcttca tattttacat
    44821 aaagctcttt ttaaattcaa ataaatttaa ctttgattaa tttttaaata tccaattcat
    44881 cttctttttc ccagcttaaa gctctcgata cagctttttt ccatccttta tataatttac
    44941 atctcttctc ttcactcata tttggattaa actctttttc tactgaccac tttgaagtaa
    45001 tttcatttct tccaatatag aatccaacag acaaccctgc taaataagca gctcctaaag
    45061 ctgtagtttc tactattttg ggtctatcta tatctacatt taatatatct gattgaaatt
    45121 gcattaaaaa attattatta cttgctccac catcaacttt taatgatttt agttttaatt
    45181 ttgaatcgtt ttgcattgct tctaaaacat cctttgtctg ataagcaatt gattccaatg
    45241 tggctcttac tatatgttct ttttttgctc ctcttgtaag tcctaaaatt gaacccctag
    45301 catacatatc ccaatatgga gctccaagac ctgtaaatgc tggcactaca tatacaccat
    45361 tagtatcctc taccctattt gcatacattt cactatcttt tgcagattca attatcttta
    45421 attcatctct aagccattga acagatgctc ctccaataaa tatacttcct tctaatgcat
    45481 atgttacttt tccatcaact ccccaagcaa ttgttgtaag taacccatgc ttagatttaa
    45541 ctatgttact gcctgtattc ataagtaaga aacaacccgt tccataagta ttttttgcag
    45601 taccttcttc aacacaattt tgaccaaata atgctgcttg ttggtctcca gcacatcccg
    45661 caataggtat tttagctcct gataacatgc gctcatctgt atgaccataa acatagctag
    45721 aaggttttac taatggcaac atgcttattg gtatgtccaa ttctcgtaat atatcctcat
    45781 cccattctaa atcatttata ttgtacatca ttgttctaga tgcatttgag taatctgtta
    45841 catgtacttt cccacgagtt aaattccata ttaaccatgt atctatagtt ccaaataata
    45901 actctccttg ttctgctttt tccctagctc cttctacatt atctaatatc cattttactt
    45961 ttgttgctga aaagtatgca tctattaaaa gacctgtttt ttcttttatt gattcttcca
    46021 atcctttatt tttaagttca tcacatattt ctgatgttct cctacactgc catactattg
    46081 cgttataaat aggtttacca gtatacctac tccaaacaac cgtagtctct ctttgattag
    46141 ttatccctat cgaagcaatt tcttctggtc ttatacctgc tgtttctata acttctctca
    46201 ttacaccact ttgtgacccc catatttcca tagggtcatg ctctacccat ccagcttttg
    46261 gataaatttg attgaactct ttttgtgcaa ttttcactat ttcgcctttt ttattaaata
    46321 gtatagctct tgaactggtt gttccttggt ctaatgccat tacatacttc ttttccatca
    46381 ccatattctc cttatcatat aatatttaat ttattaaaaa gaaaaattta atatcacata
    46441 tttcaataaa taatcatact taagtacaaa tttaatataa tagatattta taaaaagaca
    46501 cttattttct atcatatcta tataataata ttatacatta tagcttacat attgattaat
    46561 aaattttaaa ggagtataat aaacagtgtt cataataatt ttaataaaag aggtggtaat
    46621 atgccaaaga ttttagaaaa tgtaaaagaa gatatattaa aagtatctcg ggatatgatt
    46681 ttagaagaag attactcgaa tattagcata aggaaaatag ctcaaaggtg tggtataagt
    46741 gcaggtacag tatataatta ctttaattca aaacaagaaa taatagaata tatcacaaaa
    46801 tctgaatggg atttattgat aaggcgaatt gaatactcca ataaaaacac tgaagattac
    46861 ataaaaaaac taaacattat ttttactgaa ataagaaatt ttataaacaa agttcataat
    46921 atccaataca atgacttttt aaacactttt gaaacagaga gattttttga aatgaaaaaa
    46981 cacaaagacg actttcatga acagctttca aataaagtat atgaagcttt agaaaaagaa
    47041 agttttttta ataatgacaa attagtatgc aatatcataa taaaaatgtt tttttcatat
    47101 tcaacatatc ttcatataga atttgaagat ttaaaaccct atattgaaaa attaatacat
    47161 taaggtggtg tttaccttga atcataatac tagtattaag aacaaggaca gtaatccaaa
    47221 aatattttta gtacttacac tttatctatt aggtatattt atgggagcta ttgatactgg
    47281 aatagtatca ccagcaagaa cgattataca aaatagcctt ggagtaaatg aaaaaacggg
    47341 aatttggatg attaccatat acacattaac atacgcttct gtaattccta tctctggaaa
    47401 attagcagat aaaataggaa gaaaatatgt gtatctagtt agtatatttc tatttggtag
    47461 tggttcatta atatgtggat tatcatcact attttccaat ttctatattt tattaattgg
    47521 tcgtgttatt caagcaattg gtggtggtgg aatcatgcca attgctacag cagaatttgg
    47581 aactaccttc ccagaaaata aaagaggcat ggctttaggt ttagttgggg caacatatgg
    47641 tattgccaat attttaggtt caagcattgg tagcacaatt ctaagtatct ttggaactca
    47701 aaattggaag tggctatttt ttgtaaacct tccaatctgt ttaatcatac ttattggtgg
    47761 agttttctgt attaaaaaca ataagtctga atctaaagaa aaaatagata agcttggtac
    47821 attgatgttg atatgtataa tcgtatcact attatatggt cttatgaata tagacttttt
    47881 taattttaaa aattctatac aagatatatc agtttatcca tacttattga catttattgt
    47941 acttatacct attttcatat ttattgaaaa tagagctaaa gaccctattt taagctttga
    48001 atatttttta aatccgagaa tattgatagt acttatttta tctttaattg ttggtattgg
    48061 aatgatgggt atggtattcg ttccacagta tgctgaaaat gcattaaaga taaatgctgg
    48121 ttctggtgga tattttgtag ctatattggg attatttgca ggtattgctg ctcctttaag
    48181 cggaagactt attgacaagt ttggggcaaa gaaaatacta ttactaggat tttctgtatc
    48241 tatgataggc tctctttacc tagttttaat tgctctaaaa accaatactg tatttagtgt
    48301 atgtgtaagt ttaatattta tgggattagg aatgggcttt actatgggaa ctcctctaaa
    48361 ctatatgatg ttatcaaata caagattaga agaatctaat tcagcacttg caacattatc
    48421 cttgatacgc tcaattggta cttcaatttc tccagctata atgattggat ttatagcaca
    48481 tgcaggatta tctgtgcaag ataatattat ggacttagtt ggaaagccct caactcctaa
    48541 aatagttcaa cttgaagaac ttgaaaacat gatagatgac ttaaaatcag accctgaaat
    48601 ggcaaaaaat ttaaaaaatg tctctatccc aaatatgaat gatacttcaa atataaatat
    48661 ggacatgaca ggtggcaaac ttccaaaatc cttacttaat aaagttcagt cagcagatac
    48721 aaccaacatt accaatataa caaaagaaat atcaacaaca atgtttgatg aaaaagttcc
    48781 atctataatt actaaaatac agaaaaatgt acaaaaagga atagatggaa cacaaagtgg
    48841 aataaacggt attgaagatg gtgaaaataa actaaatagt ggtattaaag gagttcaaac
    48901 tggtattgac aatatggtaa aagctagagc tggtattaat caaggaatag atggtgtaaa
    48961 aaaaggtatt gctggtgttg gcaaaggtat aaaaggtatg gaacaaggtc ttgaaaaaca
    49021 agatgaggcc atcaaggaac ttacaactgc ttataataaa atacctacta cagaaaaaac
    49081 tcctactgat aacgaaaata actcaaatga acaaaaccag agtaatacca gtaattctga
    49141 atcagacgac actaagaatg attctacaga aaataagaat aacaattcca gcgagaataa
    49201 accaaatgta aatgaacaaa aagaaagttt aaatgctcaa atacagcaac taaaaaagac
    49261 aagagatgac ttaaatacaa agttacaaaa aaataaaact caaaagaacg aattaagtaa
    49321 aaaactaaga tcaatggaat ctcaaaagaa agagctacaa agcaagttaa ataattctat
    49381 aaaccaaaag aaagacatgg aaaaaagcct tgatacaatg caacagcaaa aaaaatcact
    49441 ccaagcagtt ttagcaaaga cacaagaggt aaaaactgaa ataccaaagg cttttgataa
    49501 atcaaaattg gattatataa attccataga aaataataga acaaaaatag aaaatacact
    49561 acaatctact ctaaactcag gatttaaaca gatgtatata acagtattct gtgtaaatct
    49621 actagcattt ataatattat tgttctataa agaaaataaa actagataaa agagtgttat
    49681 agtattatat tgtaaattta tcttattctt aaatatttta ccctaaagaa taaattcata
    49741 aaatttttgt aattgattaa tataaattac aatataatac tatttttatc ttaatctttt
    49801 tctcttttac agacaatcaa aaagcaatct tagtttatcg aaataaattt atacaatcta
    49861 ttcatacacc cctttacatt tttataacaa ttaaatctat tgttatatat acaaatcaaa
    49921 ataaaccata tattttcaac tataatatgt taaaatcata ttatgagcat attaatttaa
    49981 gcaaaatgtc atttagactt taatttagta gttttatatt ataaatttat atatttttaa
    50041 tttcaaatgt catttagaca ttactcataa aaagaaagga gtgtattttg tggatacttt
    50101 aggaaaaaga attgcttatt tgagaaactc caaaaaactt actcagcgca aacttatgga
    50161 tattttaaaa tttgaaaact taggcaagta tgaaacagga gatagaaaac ctaattgtga
    50221 tatactaatg tcaatagctg attattttaa tgttacgact gactggcttc tctatggtaa
    50281 agagaatgta aatgtcaata gtagtgtaaa agaagataaa gaagattact tacatgttac
    50341 taatgatgaa atgatgatat taaatctata cagacaacta aacgaacgtg ataaaataaa
    50401 aatagaagga atacttgaac ttaagatatc tgaatataaa gacttaaaaa agcattcctc
    50461 taataataat gaagataaaa tggtttaaac atacataatt tgatacgatt ttacatcatc
    50521 tattaacctt ctttttttgt agtatattac taaaatatgg atattggatt atttaaaaac
    50581 aagtatagtc taatttcaag cacgtttata atatttagat tatcttatcc atattttagt
    50641 ttaagtactt tgaaaaatat aatacatttc tatgtataat ttatattcct aagaaatgca
    50701 ttactcatgt ttttaattct tccaacatct ttctatacac aattgtacat ccttcataat
    50761 tcccctcttt aagaaggatt gaacatgtac tagaatattt agttaaagta tttaatcttt
    50821 ccatatttaa gctttttata ttactaagtg ctgtaataaa atcatcaatt gctctacaac
    50881 actctataac cccatctgaa tccaatttgc acacaagaat attcacctac tttatatact
    50941 atttattaat catcttctga atattctata ttaagtaatt gataaattga tgatttatat
    51001 tttttacctg ttcttcttcc atttaaaata gctgacaaat agttttcatt aacacctatt
    51061 ttcttcgcta attccctttg agtcatattt aattcaataa gtctttgctt gacttgcact
    51121 cccaaaaaag gtatccattt ttttcgagca tccatttatc aacttccttt ctaagtgatt
    51181 tatatttact tttatattac tttagcttac gcaccccctc tatttagtat atatttttaa
    51241 tatgtacaca tattaagtat ataaatttat ttaatactaa ataagatttt ttgattactt
    51301 tgtgctaaaa ttaggatgta aattcgtatc attaagttaa ttataaagtc attttgacct
    51361 taagtcaatg gtttttatgt cattttgacc tttaatttga aactatttac atcttaaaaa
    51421 gtctttttga cattaattga atggagagtg tttatggata ctttaggaga aagaattgtt
    51481 tatttgagaa aagcaaaaaa ccttaaacaa tatgaactag aagaaatgtt aggctgtgac
    51541 aacttaagta aatttgagag aaacattaga aaaccaaatt atgaaatatt aaaatctata
    51601 gctgagatat ttaatgtttc agtagactgg ctattaaatg gagataatct atcacataaa
    51661 tcagatttaa tttgcgattc ctcctcaaac tatccactta atagcataaa ctctaatgaa
    51721 ataaagcttt taaacaactt tagaaagtta aatgattatg ataaagccaa aatagaaggt
    51781 atgattgaat taaaacttca tgaatatgaa aaagagaagg atttaggaaa aattgagtat
    51841 aacaaaaata aagatgagaa aatagataaa taatttttat gttgcttttg atacgatttt
    51901 acatcatttc tttgttctaa tatttttatt tcatttattt tcttttttat aattttatga
    51961 taaaataatt agtatatttt gctttacttg aatgtaatta tttatacaaa agtcaaacat
    52021 aatataaatg tagtaaattt ttagtttcaa gtaatatctc gttattataa ctaaatattt
    52081 attaaaatta ggaggataaa atgggcttaa gagacaaatt cgcgcaatca tttgctagat
    52141 caaaaactat gagtggccct gagaaaaagg ctaatgaaat aatgggtaaa ttgcttctta
    52201 agaaagctat attacctatc gttttaatgt tcgtgataat aatcgctgga gctatgctta
    52261 aaatcaattc ttgggttaca cttggcataa atttagttat tgctgttggt gctttcttct
    52321 acataagaaa ttctagtaaa aagtatcaga actttaaacc ttatgttggc aatttgatta
    52381 gtttagagaa aaaaggtaaa aaagagtacg ttgctattat aaaacaaggt aagttgccag
    52441 ttaagttaca aatagcttat ggtggtgaag accttgaaca tgttaagaaa aatcaaatgg
    52501 ttcagataag ctataatcca gatgctaaaa tagctatttt ggttaataga caataattta
    52561 ataaaaaaaa ggagttgtct taaaattgat tttttctaat caaatttaag cttaactcct
    52621 tt
//
LOCUS       DACTZW010000022        51983 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.022, whole genome shotgun sequence.
ACCESSION   DACTZW010000022 DACTZW010000000
VERSION     DACTZW010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 51983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51983
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.022"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(136..444)
                     /locus_tag="JAM15_06680"
     CDS             complement(136..444)
                     /locus_tag="JAM15_06680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HAT6797943.1"
                     /translation="MKNNNLNCAATNCAYNTSGYCYAGSIKVDGMQATTTENTYCASF
                     EDKYTSGITSRSNETNQVDTDNIHCEAVKCKYNKNELCKAEKVHINERNASCETFEMK
                     "
     gene            complement(504..932)
                     /locus_tag="JAM15_06685"
     CDS             complement(504..932)
                     /locus_tag="JAM15_06685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797944.1"
                     /translation="MNNKLHELEKNLPETSCSFCTHLSFKGPSLDYRYDIRCVISDTK
                     PDFRGCCEYFEPEYTELNTGDLDNLYINFLETCLKVNYNDYINSMYWKLFKERTLLEN
                     NFKCSICGSTENVDVYHVNKNLGRETSKDVVVKCDKCNCK"
     gene            complement(1155..2612)
                     /locus_tag="JAM15_06690"
     CDS             complement(1155..2612)
                     /locus_tag="JAM15_06690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HAT6797945.1"
                     /translation="MTTFLIGLAILLIGGALYGAYCEKVFGPDDRKTPALAQSDGVDY
                     VPMKKWKNSLIELLNIAGTGPILGPIQGILFGPIAFILIPIGCVFGGALHDYMSGMIS
                     IREKGAQMPSLISRFLGNKVFQVYNIFLCLLMLLVGAVFIYTPGDLVVTQILNMKSTI
                     NNPVVWIVYGLIFLYYLCATLFPIDKIIGKVYPIFGAILLLSAAGVGIGIFTQGYDLA
                     NLSLANWKGIHPDGIPLIPTFFVTVACGIVSGFHSTQATLIARSVSNEKEGKTTFYNM
                     MILEGLIAMIWAAAAMGIYNKGIPKELVGSPDVIGLVARDLLGSIGGIIAIIGVIVLP
                     ITSGDTALRSLRLMLADYFHYDQKEKKHRVILSICIFIPVIAILIFAKLSASGFNILW
                     RYFSWSNQTIAIFAFAMITVYLIIKEKNYIISLIPGMFYSFVIFSYIFNAQIGFNLNI
                     NISYVLAAIFTVLYAILTVRSGRKLKSKADTKLAD"
     gene            3030..3944
                     /gene="nadA"
                     /locus_tag="JAM15_06695"
     CDS             3030..3944
                     /gene="nadA"
                     /locus_tag="JAM15_06695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HAT6797946.1"
                     /translation="MDKDLTYQIKELKKEKNAIILAHFYQSPEIQELADAVGDSYYLS
                     EIARDCKEEVVVFCGVRFMGESAKILSPEKTVLMPVSNAGCAMADMVDEEGVIKLKQQ
                     YPNALVVCYINSTAKVKAHCDVSVTSSSAIKILENIDNKEIIFLPDKNLGGYIAEQFP
                     DKNFIFWDGYCKYHNNIRAEEIIELKDKYKNAEVLVHPECKKEIRDLGDYVGSTSGII
                     KYATNSKNKDFIIATEEGILHELKKNNPNKNFYIPGGKILCTDMKKTTLENLYSTLKN
                     MENEVIVEDEIMEKALNSLLNMHKLAEG"
     gene            3957..5258
                     /locus_tag="JAM15_06700"
     CDS             3957..5258
                     /locus_tag="JAM15_06700"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HAT6797947.1"
                     /translation="MNLEQDVLIVGSGVSGLYCALNLDKSLNVLVVSKSTIENNNTYL
                     AQGGISTARNIDDIESFVEDTMKAGQYKNRVEAVQVLADESIENVGQIVEYGMPLDKE
                     NGEIDYTREGAHSVNRIVHSKDNTGEVVFKTLLKEAKTRENITLIEDAYLLDILKDGN
                     KCIGARIFKSKKEIHVFSKIVVLATGGIGGLFKNSTNQRHLTGDGIAIALRNNIKIEN
                     LEYIQIHPTAFYEENNEGRRMLISESLRGEGAKLLNKNKERFVDELLPRDVVSKAIFE
                     QMEKDKLPYVYLDATHLDSEYLINRFSFIYNECLARGTDITKECIKVSPAQHYFMGGI
                     HVDLDSKTSMENLYAVGEISCTGVHGANRLASNSLLEGLVFSKRAAKNINSVIDNVKV
                     KFIDVPDMDIDIEQVKKENKILVIKEIERTSEDFGDELFDY"
     gene            5239..6075
                     /gene="nadC"
                     /locus_tag="JAM15_06705"
     CDS             5239..6075
                     /gene="nadC"
                     /locus_tag="JAM15_06705"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HAT6797948.1"
                     /translation="MNYLIIDRMIQDALIEDVPSEDITTNSIVDENSKSTVDLICKQD
                     GIIAGLGVFKRVFEILGDVDVKLYKNDGDRVKNREKIAVLTGSTRNLLVGERVALNYL
                     QRMSGIATITSRYVEKLEGTNTKLLDSRKTIPNLRILDKYSVKVGGGCNHRFNLSDGI
                     LLKDNHIGAAGSVKKAVELARKNTSFVRKIEVEVETLDMVKEAIEANADIIMLDNMSL
                     EMAKQAVDIINGRAIVEFSGNVNLDTIEDIGKIGVDVVSVGALTHSVKALDISMKNLR
                     NI"
     gene            6331..6663
                     /locus_tag="JAM15_06710"
     CDS             6331..6663
                     /locus_tag="JAM15_06710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur reduction protein DsrE"
                     /protein_id="HAT6797949.1"
                     /translation="MKVAYIFSSTNTHKILDKMIIPQLEQGTHGVDVLGMFFFMDNTL
                     FLSKGNPVGERLSKLHEKTDMIIMACDQCAIERGIENNLVDGATIGCFPNLYACLGSA
                     GVDQVITL"
     gene            6825..7010
                     /locus_tag="JAM15_06715"
     CDS             6825..7010
                     /locus_tag="JAM15_06715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797950.1"
                     /translation="MSEKYADKLEIKLYQAGKDFSYIKKYGIITKGTLIINQKKKYDR
                     LNKDTIERAIVEAINNN"
     gene            7037..8122
                     /locus_tag="JAM15_06720"
     CDS             7037..8122
                     /locus_tag="JAM15_06720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HAT6797951.1"
                     /translation="MNILEIVLNGVKDTIVASIVTLNGASGWLMISFILAGVLHNVLT
                     PRRFQKQLGNKKFSSLIKSTISGMFLPICSCGVIPLGISMYYSGAYLGPVLAFMTSTP
                     IINPIAVVLCLGLLGPKVTIIYLIAGFLVPFLVGFLGNCFGKEELSLHNDSEEEVIEL
                     EEEKRSFMGNMIDGLKWSFGELALTISKYVVMGMVFAGFITTIFPNSIIQKYLGNPGL
                     LSLGSIAILACVMYVCAVGHIPFIAALVASGASPGIAITFLIAGAATNLPELISMFKL
                     IGKRTVIIYSVTLTLSSIIIGYITNLLLVNNNSVNLDATNSSIQLANKLMLNIPDSFE
                     YVCTILIILFAFKSIIPKMKEVIGNHA"
     gene            8115..8573
                     /locus_tag="JAM15_06725"
     CDS             8115..8573
                     /locus_tag="JAM15_06725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797952.1"
                     /translation="MLKKIVIISCIVVVLIILSKIVDDNIKEDASIPNVNKETLEYFR
                     KNYKEDIITCAEEDLNNDGKKDLVVIYKKSNNSNEMVVVVSDKNSHYITKPIPAPIEN
                     QTITFKNIDDKAPIEVIVSGSKNGNVGYAIYRVEGKKFVDLFGEDMDKCC"
     gene            8608..9699
                     /locus_tag="JAM15_06730"
     CDS             8608..9699
                     /locus_tag="JAM15_06730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAT6797953.1"
                     /translation="MKLSKKIQALILFGVMGTSILTGCSSKPKEKEEAKTGKDDYTIT
                     VGYYNCDHMTAGPVAESAGIYKDLGLNVKTVGNGKVPEAMAAGKMDAGYIGTKGLVGA
                     IPKGSPITIAANNHTGGSEYLIVSKDIKEPKDLIGKKIATDMSDFLWTSDYGPETGLP
                     TDPSKYEVVNMDSDKDKYLALKTGKIQAFTSCDPWGSVAENDGAGKIIASTQYKEKAN
                     GKEYNCCSFSLNKNFIKEHPDLAKKLVLAHTKAIEYIYTNPAEAAKIFAKYYNVEEEV
                     ALRTIYKKTVGEGRTLTWKVTGEEYKNNLQMYKDLKALDDIPKYEDTIDTSLLDSCGA
                     DDFDKFIKEKVNPEFPEGMSYEDWKAKVL"
     gene            9704..9928
                     /locus_tag="JAM15_06735"
     CDS             9704..9928
                     /locus_tag="JAM15_06735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797954.1"
                     /translation="MENMKNIIILFIIILGSIFIIFFNFEDKEEIKGKLRIGVSDDTS
                     GFVINYMVNRDYFENIKVSDIMDIFTINDC"
     gene            9938..10501
                     /locus_tag="JAM15_06740"
     CDS             9938..10501
                     /locus_tag="JAM15_06740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797955.1"
                     /translation="MQWALSSEEIDIAIICKDAAKQYVNVNSGFEIVGTVVQNSDIFL
                     LSDNNPEKIGVIQNRDYQSELVKKYYKNVEVAPLLGTALAYGLESNLVDGVVIDCIKS
                     IGLEGKRKSTTKLGDYDTYVLVVNKEFKKSKAYSDFITLYNKSVDALKNKATFKKVLK
                     EYRNIRNIDMEEISNWKLKFLKIKAID"
     gene            10462..11091
                     /locus_tag="JAM15_06745"
     CDS             10462..11091
                     /locus_tag="JAM15_06745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6797956.1"
                     /translation="MEIKISKDKSDRLTKKKTDGSMDILYKIILLVIIFLVWHFAAKD
                     IGSSLLLPMPVDVIKGFFFCVTDAETVTNLFITLQRVLKGFMYALLFGLPIGFIMGFS
                     KTFERVLSPVVDSVRQVPIMAWVPLTIVWFGIGDGPTIFLIAFSGVFPIILNTIQGVR
                     AISKDYYNAARSMGASPIVIFTNVIVPASLPDILTGSRIAISTGWMSVI"
     gene            11131..11268
                     /locus_tag="JAM15_06750"
     CDS             11131..11268
                     /locus_tag="JAM15_06750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAT6797957.1"
                     /translation="MVQAQTLMHTDVLIGLMIFAALIGFIIDRVLKFINKILCRWRFA
                     D"
     gene            11268..12020
                     /locus_tag="JAM15_06755"
     CDS             11268..12020
                     /locus_tag="JAM15_06755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6797958.1"
                     /translation="MKLSVRDINKTFVNNRVHTKVLEDISMDIDDGQFVCLLGPSGCG
                     KTTLLTIIGGFQKSERGDVFINDKRVKKPGIDRAFIFQNYALFPWKTIRGNVLFPMKQ
                     QKIPKEKREEMLEELLVMSDLKGKEKLFPHQLSGGMKQRVAMIRALACNPEVLLMDEP
                     LGAVDFQMRQNLQEELERIWIKKKITALMVTHDVDEAVYMSDRVIVMSRDKGRIIDDI
                     NIDIPRPRIRGSQKYEEYKNKLTDTLSKCYEV"
     gene            12033..12518
                     /locus_tag="JAM15_06760"
     CDS             12033..12518
                     /locus_tag="JAM15_06760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797959.1"
                     /translation="MSQIEKYNSLDNTQQKIRISIMDMIIDKGSSVTLQEVTEYVSKK
                     LNIEKEYIERTLQYFIYKNIMVVDGNSINFIYPVSALPTNHKVTLRDNRSFSAMCAID
                     AIGTSCTFNQDIKINSICSATGKEIEVIIKNEKIEYVNNPNLRVLHINLDKHLNWAAS
                     C"
     gene            complement(12810..13631)
                     /gene="yidA"
                     /locus_tag="JAM15_06765"
     CDS             complement(12810..13631)
                     /gene="yidA"
                     /locus_tag="JAM15_06765"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HAT6797960.1"
                     /translation="MYKLIALDIDGTILNTQKRITPEVFESIQEAKRAGAKVVITTGR
                     PLPGVKELLNQLNLTDEGDYVICFNGAIIQEVKSEKIIHDVEMTLDDFDFIYNNVCKK
                     YKTKIHINTMTNLITPNETPGKYTLHEAKLNNIEVKYIQKDKIDESIKICKIMIVDEP
                     ERLEEIIQQLPKNLFNKYTIVRSAPFYLEFLGKTTNKGTALKTLCTNLNIPIENAIAV
                     GDEENDQHMIKYAGLGVAMGNARNSIKEIADYVTDTNNENGVAKVINKYILNKAI"
     gene            14124..15818
                     /locus_tag="JAM15_06770"
     CDS             14124..15818
                     /locus_tag="JAM15_06770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HAT6797961.1"
                     /translation="MKFSEFKYERPNYNSMKKEFLSCVEDINNSRNYKEQQKNIHKIN
                     LLRNKLETLSNIASIRYSTDTFNKFYKEEKNYWDEYMPLYEELNSYFYNAIVNSKFKY
                     DLIKEFGEQFFTIVEYSLKSFSKEIISELQEENKLCSEYTRLLASAEIMFDGKIRNLS
                     GMGKFMYSKNRKTRELANKAYYNFFEENETKFDDIFDKLVKLRDKMSKKLGFEDFVEL
                     GYVRMMRSDYREYMIKNVRKQVLKYVVPMANELYEKQAKRIGLEYLSYIDEGVEFLTG
                     NASLKGDSRYIIQNGKRMYSELSKETNEFFDFMLENELMDLETKKGKGAGGYCTYIPD
                     YKSPFIFSNFNQTADDIDVLTHEAGHAFQLYMSRWIDMPEINFPTLDSCEIHSMSMEF
                     ITWPWMDLFFKEDTDKYKFTHLSSSIKFIPYGVIVDEFQHYIYKNPNVDKSKRKEIWR
                     FLEKKYLPHRKYGDNSFLERGCWWFKQGHIFKNPFYYIDYVLAQICALQFWKKMIQDR
                     DAGWKDYINICKVGGTKSFLDIVSMGNLYSPFDDGCIESIIGDVKSWFDEINDSKL"
     regulatory      16150..16260
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            16364..16735
                     /locus_tag="JAM15_06775"
     CDS             16364..16735
                     /locus_tag="JAM15_06775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine reductase"
                     /protein_id="HAT6797962.1"
                     /translation="MIIITNNPKVKEEVQGREVLFKDTTYIGILEASRDLIHEGYELL
                     SHPLYGSVKPNETPYRTVILKKGNRLDINSLTLIEEAIITASKFQNNKKTPKWTESVQ
                     DDFRVIDYDIFYNTIQRMQYE"
     gene            16831..17778
                     /gene="trxB"
                     /locus_tag="JAM15_06780"
     CDS             16831..17778
                     /gene="trxB"
                     /locus_tag="JAM15_06780"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HAT6797963.1"
                     /translation="MENVYDLVIIGSGPAGLAAGLYGARAKLKTLILEKDKTGGQIVI
                     THEIANYPGSVPNATGPSLIARMVEQCKEFGAEMLRDNIVDTELDGDIKVLKGEKAEY
                     RAKAVIIGTGATPRKIGCPGEKELTGKGVSYCATCDADFFEDFEVFVVGGGDSALEEA
                     MYLTKFARKVTIVHRRQGFRCAKSVEEKAKANPKIEFLLDTVIEEIKGDGILESVVFK
                     NKVTGETHEYFADEEDGTMGVFVFVGLDAQTDLFKGKVDMDEKGYIITDEDMRTNIPG
                     VFAAGDCRSKTLRQVVTATNDGAIASIVAEKYIDEKFGN"
     gene            17863..18180
                     /locus_tag="JAM15_06785"
     CDS             17863..18180
                     /locus_tag="JAM15_06785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HAT6797964.1"
                     /translation="MLDLDKATFEEEVLNAEGFVFVDFWSEGCEPCKALMPDVHKLAE
                     TYGDKIKFCKMDTTKARRLAIKQKVLGLPTMAIYKDGEKVDEVTKDDATVPNIESMIK
                     KYL"
     gene            18449..19735
                     /locus_tag="JAM15_06790"
     CDS             18449..19735
                     /locus_tag="JAM15_06790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006807544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HAT6797965.1"
                     /translation="MRLELGKIFIKDIQFGDVTEVKDGVLFINKQEMLQEIGGDEHIK
                     SIDIELARPGESVRITPVKDVIEPRVKVEGNGGIFPGIMSKVDTVGEGKTHALKGVAV
                     VTTGKIVGFQEGIIDMTGEGAKYTPFSKLNNVVVIAEPIDGLKQYAHEKAVRMIGFKA
                     AMYLGEVARNLTPDEVSVYETKPLLESIKEYPELPKVGYVYMLQTQGLLHDTYVYGVD
                     AKQIVPTLLYPTELMDGAIVSGNCVSACDKNPSYVHINNGVVEDLYARHGKDINFVGV
                     IITNENVYLADKERSSNWTSKLCKYLGLDAVIVSQEGFGNPDTDLIMNCKKIEMQGVK
                     TVIVTDEYAGRDGGSQSLADADVRADAVVTGGNANQVVVLPKLDKVIGHLEVVDVIAG
                     GSDGSLRADGTIEVEIQAITGATNETGFGHLTAKGY"
     gene            19847..20320
                     /locus_tag="JAM15_06795"
     CDS             19847..20320
                     /locus_tag="JAM15_06795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:19979..19981,aa:Sec)
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase complex
                     selenoprotein A"
                     /protein_id="HAT6797966.1"
                     /translation="MSLLSNKKVLIIGDRDGIPGPAIEECVKTVEGAEVVFSSTECFV
                     UTAAGAMDLENQNRVKDAADKFGAENVVILLGAAEAEAAGLAAETVTAGDPTFAGPLA
                     GVALGLSVYHVVEEPIKSLFDESVYEDQISMMEMVLEVEEIEEEMSGIREEFCKF"
     gene            20352..21662
                     /gene="grdB"
                     /locus_tag="JAM15_06800"
     CDS             20352..21662
                     /gene="grdB"
                     /locus_tag="JAM15_06800"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:21399..21401,aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HAT6797967.1"
                     /translation="MGKLKAVHYINQFFAGIGGEEKADTKPHVAETLPPISLQLDKLL
                     GEDIEIVGTVVCGDSYFNENIDSASEEVLSMVKGFEPQLFIAGPAFNAGRYGVAAGTI
                     TKVVKDALNIPALTGMYVENPGADMFKKDVYVVETSDSAAGMRKALPKIAKLAVKLAN
                     GEEIGTPKDEGYIARGIRVNYFHEDRGSKRAVDMLVKKIKGEPFETEYPMPNFDRVDP
                     SKAVKDLSKCKIALVTSGGIVPKGNPDRIESSSASKYGTYSIAGVMDLTEETYETAHG
                     GYDPVYANLDADRVLPVDVLRDLEKEGVIGKLHETFYTTVGNGTSVANSKKYASEIGA
                     ALVADGVDAVILTSTUGTCTRCGATMVKEIEKTGLPVVHMCTVVPISLTVGANRIVPT
                     IAIPHPLGNPALDPTEEKALRRGLVEKALNALTTEVDGQTVFEK"
     gene            21919..23451
                     /locus_tag="JAM15_06805"
     CDS             21919..23451
                     /locus_tag="JAM15_06805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002846562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine reductase"
                     /protein_id="HAT6797968.1"
                     /translation="MTYPVLKGAGYVLIHTPDMIVQNGSTCTVERATNPDSEFLKEVS
                     NHIRSYEDVVNYMPNQVYIGNRRPEELRDLPMPWCEQKIEGTRNGKFGEIMPQDEFIA
                     LMQISDAFDLVKLSQEFIDEVKPKIENNYPEIAPFVGKLKGDDIEEGKELVATHIAEG
                     LYHDGKFVGYVKRAHDVDVNLNAHTMFENLVVKASGVLSAIQMLRHSKIDPAEIDYVI
                     ECSEEACGDINQRGGGNFAKSIAEIAGLQNATGSDTRGFCAAPTHALIQAAALVKAGI
                     HKNVMVVAGGASAKLGMNAKDHVKKGLPVLEDVVGGFAVLVSENDGVNPVIRTDLTGK
                     HTVGTGSSPQAVMTALITSGLDRANLKITDVDVYSVEMQNPDITKPAGAGDVPEANYK
                     MIGALAVKRGDLEKKELKDFVSNKGLPGWAPTQGHIPSGAPYIGFLIDDLTTGNRNRA
                     MIVGKGSLFLGRMTNLFDGVSFIAERNTGVTEETSGISKDEIKKIIAESMKKLALDML
                     EE"
     gene            23462..24607
                     /locus_tag="JAM15_06810"
     CDS             23462..24607
                     /locus_tag="JAM15_06810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine reductase"
                     /protein_id="HAT6797969.1"
                     /translation="MSKKVIADVFLEVANAIESGEFGKKVKIGVTTLGSEHGVENMVN
                     GAQLAKSNLFDIVLIGPKVETDLEVVEVNDEKEMHAKMEELLDSGYIDACVTMHYNFP
                     IGVSTVGRVITPAKGKEMILATTTGTSATNRIEAMVRNAIYGIATAKSMGNKCPKVGI
                     LNVDGARQVEKCLKELKDNGYDMEFADSIRADGGCVMRGNDLLVGAPDVMVTDTLSGN
                     IFMKVFSSYTTGGDYEAQGFGYGPGVGEDYDRKVLIVSRASGSPVVANALKYAYDVVK
                     GDISNVARNEFAKVKKAKFDDIISSLTKKEVKAEKVEVKMPDKEIVTRQIAGVDIMDL
                     EDAVSELWKNGIYAESGMGCTGPIVLVNEAKGDLAVETLVKAGYTAK"
     gene            24917..25996
                     /locus_tag="JAM15_06815"
     CDS             24917..25996
                     /locus_tag="JAM15_06815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HAT6797970.1"
                     /translation="MSRVKNVVELLGTKGVDALYLTKKTNVNYISGFPDEEAYAVICK
                     DGNFLVTDSRYMELAEKVCKDFEIINWHNFDRSVAKAVKSVCDKVGIKKLGFERTNIV
                     FDKYEELKNLIEKDNGELIPTENIVETLRYVKDKDEIKNTRKACEIADKALEELIPHI
                     KAGVSEIELATKLEYFMKMNGAQNIGFETILISGAKTSLLHGKPSDKIIEKGDFVLID
                     YGAMYNGYISDTTRTFIVGGASEKQLEIYNLVKEAQNVGVENMKAGVHATIPDAEIRK
                     VVKKYEDYYYQGIGHGVGRDVHEEPFIGNYGDKIIEEGCIITMEPGIYFPGWGGVRIE
                     DTVLITKNGPERLTKFPKDLMILDK"
     gene            26109..26708
                     /locus_tag="JAM15_06820"
     CDS             26109..26708
                     /locus_tag="JAM15_06820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797971.1"
                     /translation="MYKKHKFIKNIKKAWYKIKLIDRCLIIVMAILMFQSIYNLFVNE
                     VNSQDTTTIDVVVRTTSAAIFGYFLSANFIKRPLRKYTNTDVSSNLFIDNNLPPKGQE
                     SSQNNIMNVKNTIGFTSEADNYEKKIPINNNEGFEEGETSELQIIIATVICIAALTVL
                     FVVRNFTTTTSASLGTISQMRDFVSGCVGFLLGCPSKPD"
     gene            complement(26895..27767)
                     /locus_tag="JAM15_06825"
     CDS             complement(26895..27767)
                     /locus_tag="JAM15_06825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAT6797972.1"
                     /translation="MNINYLYYFQTVCKYKNMTKAAESIHISQPSITLAIKELEKELG
                     FELFYRIGNKIELTPEGKIFLDKSKHFIKQFEDFQCDALDLGKKRKASLKIGIPTVLG
                     TFLLSKILPRFNVIYPDIELKIFEVPTFVGAKMIEESTLDFCIGIIDSDIYDDIDSKT
                     IYKTELYLVTNPKNELAKHPIISNYMLKNVPFVILSEGSYHYKIITKRLEKAKPNIIL
                     HSNQLSTIRYLLENDLASTILYKEIFQNTENLCSIPLERAITANIGVLWRRNQYISHS
                     MKLFIEYMASIHIN"
     gene            28184..29587
                     /locus_tag="JAM15_06830"
     CDS             28184..29587
                     /locus_tag="JAM15_06830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797973.1"
                     /translation="MKGSDLVKFELMDFLMNPFVLMFAAVITGILFGKIKFGKFNFGV
                     SGALFTGLFIGWLAYSLGNLIIAKGETAAGYKAATVMMGNGIISSDFFDFFLIIFVAA
                     VGLLAAKDMKAVLKKYGARFVILGVLITFIGGSMTYAMTLLSSDKGSSAYEVSGVYTG
                     ALTSSPGLAAALETAGKHAEDVSKEFEKASIKDKKEILKVVDPEGKLDVNTTTSLTQE
                     QIDKYIAYAEAGVGIGHAVAYPFGVLIVILGVNFLPKLFRMDLKEERRKYEKEMKEAR
                     DSVSGKTIPEVPFNIITFFLTCLAGYLVGGIHVFMGPLGYFTLGATGGSLIVSLVLGY
                     IGKIGVVNFRMEEKVLNILKQIGLVFFLAIVGLRYGGKVVDSIMTSGMHLALVAIAVG
                     VTAMMIGFLVGKYVFKLNWILLSGAVCGGMTSTPGLGAAVDALDSDDPAAGYGATYPF
                     ALLTKVILVIVLHKLPM"
     gene            29614..31158
                     /locus_tag="JAM15_06835"
     CDS             29614..31158
                     /locus_tag="JAM15_06835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HAT6797974.1"
                     /translation="MNNEGAFEELSGRLRNKELCDLIMNADEAAKIIEDGMVIGVSGF
                     TPSGYPKVVPLAVSERAKSGEKIKLTVYSGASLGPEVDGAWSEAGIIERRLPYQTNSI
                     LRNNINKGVVDYIDMHLSHSTQFLNYGTIPKVDVAIVEALAITEEGNIIPTSGIGNSP
                     SFIKSADKVIVEINLAKPMEMEGMADIYITENPPNRKPIEINHPKDRIGTTYIPCGLD
                     KIAGVVITNMQDKTRPLGVVDEASKKISNNIIAFLREEVKAGRLSKNLLPLQSGVGSV
                     ANAVLYGLCESEFENLTCYTEVVQDSMLDLIRMGKVTMASTTSVSPSPEGLIKFEKDI
                     DFFKDKIILRPQEISNNPEIARRIGVIAMNTAIEVDIYGNVNSTHIMGSKMMNGIGGS
                     GDFARNGAITIFSTESIAKNGDISSIVPMVSHVDHTEHDVMVIVTEQGYADLRGLAPR
                     ERAIKIIENCAHPDYKEQLRDYLNRACKSGAKQTPHILDEALSWHSKFMSTGTMKKAE
                     TFKSAL"
     gene            31189..32580
                     /locus_tag="JAM15_06840"
     CDS             31189..32580
                     /locus_tag="JAM15_06840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HAT6797975.1"
                     /translation="MEKAVENFEDLSKEYINGYIERARKAQREFECYTQEQVDKIVKI
                     VGKVVYYNAEYLAKLAVEETGMGVYEDKVAKNKSKAKVIYNNLKDKKSVGIIDIDRET
                     GITKVAKPVGVVAAITPCTNPIVTPMSNAMFALKGRNAIIITPHHKAIGCSTKTVEMI
                     NEELEKIGAPENLIQILDQQSRENTRNLISSADVVIATGGMGMVKAAYSSGKPALGVG
                     AGNVQCIIDRDVDIKEAVPKIIAGRIFDNGIICSGEQSVIVAEEMFDKIMDEFKNNKG
                     FIVRDKVQKEAFRNAMFVNKSMNKDAVGQSVHTIAKIAGVEIPEDTKIIVIEADGPGE
                     EDIIAKEKMCPVISAYKYKSFEEGVAIAKANLNVEGKGHSVSIHSNTVKNIEYAGENI
                     EVSRFVINQCCATSAGGSFFNGLAPTNTLGCGSWGNNSISENLDYKHLINISRIAYYM
                     PENEVPTDEELWG"
     gene            32773..34269
                     /gene="abfD"
                     /locus_tag="JAM15_06845"
     CDS             32773..34269
                     /gene="abfD"
                     /locus_tag="JAM15_06845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyryl-CoA
                     dehydratase/vinylacetyl-CoA-Delta-isomerase"
                     /protein_id="HAT6797976.1"
                     /translation="MALMTGAQYIESLRKLNTKVYMFGEEVKNWVDHPMIRPSINCVA
                     ATYDLAHDPEYADLMTVTSNITGEKINRFGHLHQSVDDLIKKVKMQRLCGQKTASCFQ
                     RCVGMDAFNAVYSTTFECDKAHGTNYHDNFVKYLTYIQENDLVVDGAMTDPKGDRSLS
                     PSAQPDPDMFLHIVERREDGIIVRGAKAHQTGSINSHEHLIMPTISMTEADKDYAVSF
                     AVPSDAEGVFMIYGRQSCDTRKLEEGADVDLGNKEFGGQEALVVFDNVFVPNDRIFLC
                     GEWDFSGMLVERFAGYHRQSYGGCKVGVGDVIIGAAALAADYNGANKASHIKDKLIEM
                     THLNESLYCCGIACSSEGHKTEAGNYQIDLLLANVCKQNVTRFPYEIVRLAEDIAGGL
                     MVTMPSEKDFKSDLKVGTSGMTIGEVCNKYFKASSVVSTEERMRILRFLENICLGSSA
                     VGYRTESMHGAGSPQAQRIMISRQGNINQKKELAKKIAGIKKEEALNL"
     gene            34404..34679
                     /locus_tag="JAM15_06850"
     CDS             34404..34679
                     /locus_tag="JAM15_06850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797977.1"
                     /translation="MTCGVRFCGGCNPRYERGKALTIIKEHFNGRVDFSIAQENVEYD
                     LLLIIGGCATLCASYQQYKVKNECVKMWDFSHIERVINVIESAICET"
     gene            34703..36010
                     /locus_tag="JAM15_06855"
     CDS             34703..36010
                     /locus_tag="JAM15_06855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HAT6797978.1"
                     /translation="MSWQELYQSKLCSATEAVKQIKNGDTVVFAHCVGEPPALVEAMI
                     ENAEQYKDVEIKHMVSLGSGGYTAKGMEAHFRVNPMFVSGNVRKAIENGDGDFTPAFF
                     HEVPKLLREKRLKCDVVLAQVTPPDEHGYCSLGTSVDYTYEAIKTARTVIVQVNDQFP
                     RTYGEVVHVSEFDYIVEKSQPLFELQPAKIGEVEEAIGKNCASLIEDGSTLQLGIGGI
                     PDAVMLFLTDKKDLGIHSEMISDGTLALYEKGVINGKYKNFDKEKMTVTFLMGTKKLY
                     DFANNNPAVEVKPVDYVNHPAIIMKQHKMVSINSAIQVDLMGQVVAEAMGLRQFSGVG
                     GQVDFIRGVSMGEDGKAIIAMPSITTKKDGTVISKIVSIVDEGAPITTSRNDVDYIVT
                     EYGIAELKGKSLRERARNLINIAHPSVRESLAVEFEKRFKEKY"
     gene            36030..37148
                     /locus_tag="JAM15_06860"
     CDS             36030..37148
                     /locus_tag="JAM15_06860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyrate dehydrogenase"
                     /protein_id="HAT6797979.1"
                     /translation="MEALRVVPKIFYFDTFKEFNEEFKIGKNDLVITNEFIYEPYMKP
                     LGIDTNLIFQEKFGTGEPSDEMIDSMTKEMKKYNFDRIIAFGGGTIVDICKILALDVP
                     EKSIDLFEGEVSPKKVKELVVVPTTCGTGSEVTNVAIAELKSKHTKKGLAVEETYADY
                     AVLIPETVKGLPYKFFVTSSVDALIHAIESYLSPKASPFTEMYSLQAIKMIMDGYKKI
                     VDKGEEERFNHLRDFVLASNYAGIAFGNAGCAAVHALSYSIGGAFHVAHGEANYQFFT
                     EVFKMYSRKKPNGKIIKCTKILADALECDPNCDVYGELEKFLNKLIAKKALREYGMVE
                     SQIDEFTDSTIANQQRLLANNYVELSREEIREIFANLY"
     gene            37435..38355
                     /locus_tag="JAM15_06865"
     CDS             37435..38355
                     /locus_tag="JAM15_06865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6797980.1"
                     /translation="MYKSENFSKKSVLINSFLSKFLKIIGWGLVSLFTLSALVLSTIS
                     IIIGWAVILPIQVCAVFLLIGGVCIFKGKRLGDQISRYKKYCTIINNRNIIPVELIAE
                     NTSKSLNFIIKDVQKMIDKNYFINTYIDKRNNQIVLTNEDFIPPRYEDVAYEVKEEEK
                     TDESNEVDTIINKGMNYLTQIKEANKNIKSESMGDKIVQVEDVTSKIFDVVKHDPSKL
                     TQIQKFMDYYLPTTLKLLNSYHTLEEQGIDRENITTTMESIENTMNTIVVAFENQLDY
                     LFEDEAIDISTDITVLENMLVQEGLTSGKF"
     gene            38470..39627
                     /locus_tag="JAM15_06870"
     CDS             38470..39627
                     /locus_tag="JAM15_06870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HAT6797981.1"
                     /translation="MNNLDDIPVMPTLTLDPFGEESNTNDIDNSDLLMKKDEKDPEEE
                     KLSESERKMVKEFAEKIDITNTNMILQYGAGAQKKVASFSETALKSVKTRDLGEVGDM
                     LTNLVTDLKAFSADEKEQSGFLGIFKKANNKISNLKTKYDSAEVNVDKVSKELQKHQV
                     KILKDIAMLDKMYELNLAYSKELTMYIIAGKQKLKDMKEYEMPKLREKARLSGSTEDA
                     QSVNDMVSLCDRFEKKIHDLELTRMVSLQMAPQIRLVQNSNNLMAEKIQSTIVNTIPL
                     WKNQIVLALGISHLNQAMKAQREVSNMTNELLLKNAETLKMGTIETAKESERGIVDID
                     TIKKTNQSLISTIDEVVKIQHDGRIKRQEAEVELSKIENELKSKLLEFTVK"
     gene            complement(39712..41211)
                     /locus_tag="JAM15_06875"
     CDS             complement(39712..41211)
                     /locus_tag="JAM15_06875"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002844046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HAT6797982.1"
                     /translation="MAFYFDTPSHTFSEYLLVPGFSSTDCIPANVSLKTPVTKFKKGE
                     EADIYMNIPLTSAIMQSVSDDKMAIALAKEGGISFIYGSQTIENEAAMVARVKSHKAG
                     FVVSDSNIKPDNTLKDILDLKEKTGHSTVAVTEDGTSTGKLLGIVASRDYRISRMDLD
                     TKVSEFMTPMSSIVYANKDVTLKEANNIIWDHKLNSLPVLDDNGNLMYMVFRKDYSSH
                     KENPLELLDSSKRYVVGAGINTRDFAERVPALVEAGADVLCIDSSEGFSEWQKITLDF
                     IREKYGDTVKVGAGNVVDREGFLYLAEAGADFVKVGIGGGSICITREQKGIGRGQATS
                     IIEVAQARDEYFEKTGIYIPICSDGGIVYDHHITLALAMGADFIMLGRYFSRFDESPT
                     NKVNINGSYMKEYWGEGSARARNWQRYDLGGDKKLSFEEGVDSYVPYAGSLKDNVTLS
                     LSKVRSTMCNCGALSIPELQKNAKLTLVSSTSIVEGGAHDVMLKDNRNL"
     gene            41807..43231
                     /locus_tag="JAM15_06880"
     CDS             41807..43231
                     /locus_tag="JAM15_06880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HAT6797983.1"
                     /translation="MSSSNQSTIKTSIQRVGKFLSGMVMPNIGAFIAWGLITALFIPT
                     GWMPNEKLSTIGDPMIKYLLPLLIAYTGGKAIAGQRGGVIGAAAAMGVIVGADIPMFI
                     GAMIMGPFAGWVIKKFDKFVDGKIPTGFEMLVNNFSIGIIGMLLAILGFYAIGPAIVA
                     GTALIESGVQFIVSKSLLPLVSVFIEPGKVLFLNNAINHGILGPIGIAEAKEAGKSIM
                     FLLESNPGPGLGVLLAYWMFSRGSVKQSAPGAVIIHFFGGIHEIYFPYILMNPVLILA
                     TMAGGAAGILTFSILGAGLVAAPSPGSIFALMALAPKGGLLPVLAGVAVATVVSFLVA
                     APFVKRASANQSEEDSTSLEEAKAKMSDMKSASKNSEKNIEEKQLEVNEIKKIVFACD
                     AGMGSSAMGASRFKNRIKNLDLNIEITNSSVDNLPDDTQIVVTHNTLVERVAKNNSSV
                     EIVSINNFLNDPNLDALFKRLESK"
     gene            43266..45395
                     /locus_tag="JAM15_06885"
     CDS             43266..45395
                     /locus_tag="JAM15_06885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HAT6797984.1"
                     /translation="MKKKKITSRQKKIILMIVENSKKNIPITISEIAGTLELSSRTVL
                     RDMSGIEKWFDENDFNFVKKPGVGLILEENIENQNFIIELLEEEKIEKEYSKEERNLI
                     ILSKLLVSNEPVKSYYFAKILKVSEGVLNNDFALASKWLERFDIELVRKPGLGVYLKG
                     QEKNFREAYVNLIYDSFNEKEILDMVRNISENIQTDKAIEILSENRLLNLMDRCIIRK
                     VEATLTKKLSDLDVNLADSAYIGLVVHISLALQRIKNGENITMDKEFLKELSITEEFK
                     LAKEIVKGMETDFNMDIPVDEVGYITMHIRGAKQRSSSNHKALNLDDIEIMEITNKMI
                     DLAEDEFKISLKNDERLFKDLANHLGPSINRLNMGLEIRNPLLDEIKSKYSYAYDGVE
                     KISRIIKDKLNINSIPESEIGYIAMHFASAIEKNLMMNTNINIVVACPTGIGTSRFLS
                     TKIENKFPNLNILETISAINIDEEYLKEKDVDLIVSTVELNTSLNYICVGPFMSLDDE
                     QIIKEKIKSIAQNKLINLNAKNDTKSKNKVYEQITESMNIGKDILQFLEEIRFEKFES
                     KDLSELIEDSSKIFAKSSEDIISIKESLKERLKISIPYIEESKILLLHCMSERIDIMK
                     LSIIKLENRIVLDSNEEIDNVVFMLLPKNSPSYQRQIMSEISGSLIDNIIFTNKINKF
                     SIEEMTLEVKDIVFNFYTNRLKAFIDK"
     gene            45425..45847
                     /locus_tag="JAM15_06890"
     CDS             45425..45847
                     /locus_tag="JAM15_06890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAT6797985.1"
                     /translation="MSKVLNENNIFLGLDSVSKEEAITLAGRKLVENGYVKEEYIPAM
                     LEREKVMTTYMGMGVAIPHGVNEAKKEILSSGIVILQFPNGIDFDGEKAYLLIGIAGV
                     GDEHLEILSNIAVVLDDDLTERLKNSNDKQAFMEAFAK"
     gene            45866..47017
                     /locus_tag="JAM15_06895"
     CDS             45866..47017
                     /locus_tag="JAM15_06895"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HAT6797986.1"
                     /translation="MKKAIQFGAGNIGRGFIGSLLVKSGYHVVFADVNEEILNSINKD
                     KKYTIHIRDVECIDEVIDNISAVSSIKEEIIDEIVQAEIITTAVGPLVLTKIASTIAK
                     GIKARKEKGLTSNLNIIACENAIYASSSLKEEVLKYLNKEEVEYLEMYVGFPNCSVDR
                     IVPPGKNENPLDVTVENFYEWNVEKQGFKGEIPTIVGMNLADNLMAYIERKLFTLNTG
                     HAITAYIGYLKGYKTIEESIKDKFICDIVKSAMVESGEGLIKKYNFDSEVHYKYIDKI
                     LNRFKNPYLNDDVLRVGREPLRKLSDKDRLIKPLMTAKSYGLSVDNLILGIGAALHYN
                     NSEDTQSVELQELIKSIGVKKAVAKIANISNDEELLNNIEKSYIFMKNL"
     regulatory      47123..47224
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            47407..47979
                     /locus_tag="JAM15_06900"
     CDS             47407..47979
                     /locus_tag="JAM15_06900"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HAT6797987.1"
                     /translation="MKALQEKILREGSVSGNDILKVDSFLNHQIDVAFLNEIGREFKE
                     RFKGEKVDKIFTIEASGIAIASIVSQYFDNAPVVFAKKSESKNLDKNVYETNVYSFTK
                     AREYSVKVSKKYINKGENILIVDDFLANGRAALGLKDLIEQAEANLVGVGIVIEKGFQ
                     AGGALLKANDVRLESLAVVESIDNGTVKFR"
     gene            48043..48693
                     /gene="fsa"
                     /locus_tag="JAM15_06905"
     CDS             48043..48693
                     /gene="fsa"
                     /locus_tag="JAM15_06905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002844094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HAT6797988.1"
                     /translation="MRFFIDTANIEEIKEANDLGVICGVTTNPSLIAKEGRDFIEVVK
                     EISEIVDGPISAEVISLEHKGMIEEAEKLSKIHKNIVIKIPMTAEGLKAVKVLSSKGI
                     KTNVTLIFSAGQALLAARAGATYVSPFVGRLDDISQNGLDLIEEIVDIFSVNSIEAQI
                     IVASVRNPIHVLQAARMGADIATVPLKVINQMIKHPLTDKGIDSFMKDWEGAFLKL"
     gene            48845..51769
                     /locus_tag="JAM15_06910"
     CDS             48845..51769
                     /locus_tag="JAM15_06910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAT6797989.1"
                     /translation="MDKILREIQREDKKNPYTDQELAEMLNVARSEVISVRKKNNILD
                     SRERRKKILIKDISKIVSENPQMSERKITEILIENGYNISRSAVSKLLKEENLNQSKI
                     GIKDKDPASSGKYVKVSKVVEEDGFEELIGIKGSLKEKVNLAKSAIMYPPNGLHTIIY
                     GETGVGKSELATCMYKYAIKNNIKEENSPFIVFNCADYAENPNLLIAQLFGVVKGAYT
                     GADANREGLVEQANNGILFLDEIHRLPAAGQEILFSLIDRGEFRRLGESSSNRKANVL
                     IISATTENPDSNLLQTFRRRIPMVINLPNMSERPKSERYEIIIKFFEREAKRVNKNFI
                     ITKEVMCALMNYKCTGNIGQLKSDIQVTCARAFSKSIFSSDKVIIDLDSLRDYIKSGY
                     YDCNCKNEKYSEFSVEDIYIDISELVSGKNRILSDNEISEIYNYAEKELKVLESKCFS
                     EEELKNAFIEKLDKKFNAIKNNKNLSDRRSRIDWGGQLKESTLEIMDKVIVFIKEQFK
                     HVNQGLYLALAIHIEHAIGRIKDGKTIINPSLDKIKASMPMEYELSRYIMGIVEDLTQ
                     VTFPEDELGYLAYYINKFCYNEESIKDKVKVVIVTHGKVGIEMSKVVNHILGIECTLG
                     IEIALTDSPSEGIEHVLEELQKIEARKGILVLIDMGSLVILGDEVEKRLGIRCKTVNR
                     VDTLLAMEAGKLATIEGKSLDGIIADLKKNKNYAMINTNKFSYRKNEYGKKNVIITLC
                     LSGVGTALNLKEHIEKQIKEYGTLIEVKPVAFLNNNLEEELNDIEAEYNIIAICGTID
                     IDYKNVPFISYNEVLGKNGINKVLEHLNSKQPALNIENQLNNLIHEDLILYNFEGISK
                     EYIIDTLVSKLEEGGYVDSKYILSVYKREAMGSVVMASKVAVPHGLPENVIKPAIAIA
                     RLNKPIVWDNKFMVDLVVLLALKENNKKEIRSLFSKINDQHTLEVLLNTEDKNEIKEL
                     LS"
BASE COUNT        20465 a         5751 c         9481 g        16286 t
ORIGIN      
        1 aataatttat ttttatatat aaattatgaa ttgttttaaa aaagaaccta taaatagaca
       61 tcattaataa agacatctat ttgataggtt caattttgct ttgtataaat actataaaac
      121 taaataaaaa gaaatttatt tcatttcaaa agtttcacaa cttgcatttc tttcatttat
      181 atgaactttt tcagctttgc aaagttcatt tttattgtat ttacatttta cagcttcaca
      241 atgaatgtta tctgtatcaa cttggttagt ttcattagaa cgactagtta taccagatgt
      301 atatttgtct tcaaaagaag cacaataagt attttctgta gtagttgctt gcattccatc
      361 tacttttata ctaccagcat aacaatatcc actagtatta taagcacaat tagtagcagc
      421 acaatttaaa ttattatttt tcataaataa cctcctaagt tttatttaaa cttattatgt
      481 gaagttatct aaattttata cacttattta caattacatt tatcacattt aacaactaca
      541 tctttggaag tttcccttcc taaattttta ttaacatgat acacatcaac attttcagtt
      601 gatccacata tagaacattt aaaattgttt tctagtaggg ttctttcttt aaataacttc
      661 caatacatag aattgatgta atcattataa tttaccttga ggcatgtctc aagaaagttt
      721 atgtatagat tgtctaaatc tcctgtattt aattctgtat attctggttc aaaatattca
      781 caacatcctc taaaatcagg ctttgtatct gaaataacac atctaatatc atatctatag
      841 tctaggctag gccccttaaa tgaaagatgt gtgcaaaaag aacaagatgt ttctggtaga
      901 tttttttcaa gttcatgtaa tttattattc ataagtattc ctccaaaaaa tttattttaa
      961 gtatataaac gaatagatta ttttaaaact tttatttatt tatattagag atttaggata
     1021 aatattccaa taaggagtaa atacttaagt atttattact gtattaaata aaaaagaggc
     1081 aaatctaact tgagattgcc tactttttta tcatttttta ataaaattta ttctaagtat
     1141 tattttattt agatttagtc agccaactta gtatctgctt tgctttttaa ctttctacca
     1201 gagcgtacag ttaaaatagc atataataca gtaaatatgg cagctaaaac atatgatata
     1261 tttatgttta agttaaatcc aatttgagca ttaaatatat aactgaatat aacaaaggaa
     1321 taaaacatac caggaattaa gcttataata taattctttt cttttattat aaggtaaact
     1381 gtaatcattg caaatgcaaa tatggcaata gtttgattac tccaagagaa gtatctccac
     1441 aatatattaa atccagaagc actaagcttt gcaaatataa ggatggctat gacaggaata
     1501 aatatacaga ttgacaatat aacacgatgt ttcttttcct tttggtcata atgaaagtaa
     1561 tctgcaagca ttaatcttaa agatcttaaa gctgtatctc cagaagttat tggtaaaaca
     1621 attacaccta ttatagctat gataccacca atagaaccaa gtaaatctct tgcaaccaaa
     1681 cctattacat caggagaacc tactaattcc ttaggtattc ctttattgta aatacccata
     1741 gcagctgcag cccaaatcat tgcaattaaa ccttctaaaa tcatcatatt ataaaaagta
     1801 gtttttcctt ctttttcatt tgaaactgat cttgctataa gagtagcttg agttgagtgg
     1861 aatccagaaa caataccaca agcaactgta acaaagaatg taggaataag aggaatacca
     1921 tcaggatgaa tacctttcca atttgcaaga cttaaattag ctaaatcata accttgtgta
     1981 aagattccaa ttccaacacc agcagcagat aaaagtagaa tagctccaaa tattggatat
     2041 acctttccta tgattttatc aattggaaat agtgttgcac acaagtaata tagaaagata
     2101 agtccataaa ctatccagac aactggatta tttatagtcg atttcatatt taaaatttga
     2161 gtaacaacta aatccccagg tgtataaata aaaactgcac caactaaaag cattaaaaga
     2221 caaaggaata tattatagac ttgaaatact ttattaccta aaaatctact gataagagaa
     2281 ggcatttgtg ctcctttttc tcttatacta atcattccac tcatatagtc atgcaaagct
     2341 cctccaaata cacagccaat aggtattagt atgaatgcta ttggaccaaa caatatacct
     2401 tggataggtc ctagaattgg tcctgtacca gctatattaa gcaactcaat tagactattt
     2461 ttccattttt tcattgggac atagtctact ccatcacttt gagcaagtgc aggtgttttt
     2521 ctgtcatctg ggccaaatac tttttcacaa taagcaccat ataaagcacc tcctattagt
     2581 aatatagcca agccgattaa gaatgttgtc ataatatcac cccatttata aaattttttg
     2641 gtctttgtat acatattatc taaatgtgta gatttatatt gaatttaatt ctggacaacc
     2701 tacaaattct ataaagtatt acaactaata taatttcaga aataaataca tatacataac
     2761 catgtactta gtatacaggt atttggtaat attttcaatg ttatagcaat aaagaatata
     2821 aacaaaattc tgataatatt ttacaaaaaa attaaaaaat ataaaaatta gtttaaatag
     2881 atggagaaaa aaggaaaatc aattgagaat ataaatgtct atatcttaac aatattaaga
     2941 ggtttaaaat tcttgaagaa agaatagtca agtgatataa tgagtttaca ggtgtatata
     3001 cactagtaca tatagaaagc ggtgcaatta tggataaaga tttaacatat caaatcaaag
     3061 agctaaagaa agaaaaaaat gcaataatac ttgcccattt ttatcaatca ccagaaatac
     3121 aagaattagc agatgcagtt ggtgactcat attatttaag tgagattgct agagattgta
     3181 aagaagaagt ggttgtattt tgtggagtaa ggtttatggg agaaagtgct aagatattat
     3241 cacctgaaaa aactgtattg atgccagtaa gtaacgctgg gtgtgctatg gcagatatgg
     3301 tagatgaaga aggcgtgata aaattaaaac aacagtatcc aaatgctttg gttgtatgtt
     3361 atataaactc tacagctaaa gttaaggcac attgtgatgt ttctgttaca tcttctagtg
     3421 caattaaaat actagaaaac atagataata aagaaattat attccttcca gataaaaatt
     3481 taggaggata tattgcagaa caatttccag ataaaaactt tatattttgg gacggatatt
     3541 gtaaatacca taacaatata agagctgaag aaataattga gttaaaagat aagtataaaa
     3601 atgcagaagt attagtacat ccagaatgta aaaaagaaat aagagattta ggagattatg
     3661 taggtagtac atcaggaata ataaaatatg ctactaatag taaaaacaaa gactttataa
     3721 tagcaactga agaaggtata ttacatgaat taaagaaaaa taatcctaat aaaaactttt
     3781 atattcctgg tggaaaaata ctatgtacag atatgaaaaa gacaacatta gaaaatttat
     3841 atagtacact taaaaatatg gaaaatgaag ttattgtaga agatgaaatc atggaaaagg
     3901 ctttaaattc actgcttaac atgcacaaat tagcagaagg atagagggat agacttatga
     3961 atttagaaca agatgtttta atagttggaa gtggagtttc aggattatac tgtgcattaa
     4021 atttagataa aagtttaaat gtgctagtag tatcgaaatc aacaattgaa aacaacaata
     4081 catatcttgc acaaggtgga atttcaactg ctagaaatat tgatgatata gaatcctttg
     4141 tagaagatac aatgaaggct gggcagtata aaaatagagt tgaagcagtt caagtacttg
     4201 cagatgaatc tatagaaaat gtaggtcaga tagtagaata tggtatgcct ttagacaaag
     4261 aaaatggaga gatagattac acaagagaag gagcacatag tgtaaatcga atagttcata
     4321 gtaaggataa tactggagaa gttgttttta aaactttatt aaaagaagct aaaactagag
     4381 aaaatataac tcttatagaa gatgcatatc ttttagatat attaaaagat ggcaataaat
     4441 gtataggagc tagaattttt aaatctaaaa aagagattca tgttttttca aaaatagtag
     4501 ttttagctac aggtggaatt ggtgggcttt ttaaaaattc tactaatcaa agacatctta
     4561 caggtgatgg aattgcaata gctttaagaa ataatataaa aatagaaaat ttagaatata
     4621 ttcaaataca tcctacagcc ttttatgaag aaaataatga aggtaggaga atgcttatat
     4681 ctgaatcatt aagaggagag ggagctaaac ttttaaataa aaataaagaa agatttgtgg
     4741 atgaacttct tcctagagat gtagtttcaa aagctatttt tgagcaaatg gaaaaagata
     4801 aattacctta tgtgtattta gatgcaacac atttagatag tgaatattta attaatagat
     4861 tttcttttat ttataatgaa tgtttagcta gaggaacaga cataacgaaa gaatgtataa
     4921 aggtatctcc tgcacaacat tattttatgg gcgggataca tgtagatttg gattcaaaaa
     4981 catctatgga aaatttatat gcagttggtg aaattagttg tacaggtgtt catggagcca
     5041 atagattggc aagtaattca ttacttgaag ggcttgtatt ttcaaaaaga gcagctaaaa
     5101 atataaactc agttatagat aatgtaaaag ttaagtttat agatgtacca gatatggata
     5161 tagatataga acaggtaaaa aaagaaaata aaatattagt cataaaagaa attgaaagaa
     5221 caagtgagga ttttggcgat gaattatttg attattgata gaatgataca ggatgctttg
     5281 atagaagatg ttccaagtga agatataaca actaattcta ttgtggatga aaattctaaa
     5341 tctactgtag atttaatttg taaacaagat ggtataatag ctggcttagg tgtatttaag
     5401 agagtttttg agatacttgg tgatgtagat gtaaaattat ataaaaatga tggtgataga
     5461 gtaaagaatc gtgaaaagat agctgtatta acaggtagta ctagaaactt acttgtagga
     5521 gagcgtgtag cattgaatta tttacagaga atgagtggta tagctactat tacaagtagg
     5581 tatgttgaaa agcttgaagg tacaaataca aaattattag atagtagaaa aacgatacct
     5641 aatcttagaa tattagataa gtattctgtt aaagtaggtg gaggatgcaa tcatagattt
     5701 aatttatctg atggaatatt gcttaaagac aaccatattg gggctgctgg tagtgttaag
     5761 aaggcagttg aattagctag aaaaaatact tcttttgtta gaaagataga agtggaagtg
     5821 gaaactttag acatggtaaa agaagcaata gaagctaatg cagatataat aatgttggat
     5881 aatatgagtt tggaaatggc aaaacaagca gtagatatta taaatggaag agccattgta
     5941 gaattttccg gaaatgtaaa tttagatact atagaagata taggaaaaat tggtgtggat
     6001 gttgtttctg taggagcgct tacacattct gttaaagctc tcgatataag tatgaagaat
     6061 ttgagaaata tataaatttt atattgaaat aaacttaatt aaaatagact ccttaaattt
     6121 gttttataaa tttaaggagt ctatttttta ttcattaaaa ttaataaaaa tagaaaaaaa
     6181 tcaatcaata atttaataaa aatagataaa tactatatac acttttaata atatagttaa
     6241 tatctatttt acagataaat aagaataaac ttataatata attgtatctg taaaattttg
     6301 taaaatataa aaagtatagg gggaataaaa atgaaagtag cttatatttt tagtagtact
     6361 aatacacata aaattctaga caaaatgata ataccacaac ttgaacaagg aactcatgga
     6421 gtagacgttc tagggatgtt tttctttatg gataatacct tatttttatc taaaggtaat
     6481 cctgtaggcg agagactaag taaattacat gaaaaaactg atatgataat aatggcttgt
     6541 gaccaatgtg ctatagaaag aggtatagag aataatttgg ttgatggagc tacaattgga
     6601 tgtttcccaa acctatatgc ttgtttaggc agtgcaggtg tggaccaagt tataacgtta
     6661 taaattagta taggatacaa tccatagaaa aatttatttt ctgtggatta ttttaagtaa
     6721 aagataaatt gtttaaagta ggggatgaac aaatgtctaa aattttagtt gaatttataa
     6781 acacttgacc atcttgtgat gaacatggag tgtttataaa aaaaatgtca gaaaagtatg
     6841 ctgataaatt ggaaataaaa ttatatcaag cagggaaaga tttttcgtat ataaaaaaat
     6901 atgggattat aacaaaagga actttaataa taaatcagaa aaagaaatat gatagattaa
     6961 ataaagatac aattgaaagg gcaatagtag aagctataaa caataattaa aagtttaaaa
     7021 attaggagta tcaaaaatga atatattaga aattgtttta aatggagtta aagatactat
     7081 agtagcttct atagttacac tgaatggagc atcaggatgg cttatgataa gttttatatt
     7141 ggcaggtgta cttcacaatg ttttaactcc aagaaggttt caaaaacaac ttggaaataa
     7201 gaaattttct tctttaatta aaagtactat ctcaggaatg tttttaccaa tatgtagttg
     7261 tggagtaata ccacttggaa taagtatgta ttattcagga gcatatttag gaccagtact
     7321 tgcttttatg acatcaactc caataataaa tccaatagct gtagttcttt gtctaggtct
     7381 tttaggtcct aaagttacaa tcatttatct aatagctggt tttttagtac catttttagt
     7441 aggattttta ggaaattgtt ttggaaaaga agaattatca cttcataatg attcagagga
     7501 agaagtaata gaattagaag aagaaaaaag aagttttatg ggaaatatga ttgatggtct
     7561 taaatggtct tttggtgaat tagcccttac tattagtaaa tatgtagtaa tgggtatggt
     7621 ttttgcagga tttataacaa ctatttttcc aaatagtata attcaaaaat atttaggaaa
     7681 tccaggtttg ctatctcttg gaagtatagc aatacttgca tgtgttatgt atgtatgtgc
     7741 tgtaggacat ataccgttta tagcagccct tgttgcaagt ggagcatctc ctggtatagc
     7801 gataacattt ctaatagctg gagcagctac aaatctacca gaacttataa gtatgtttaa
     7861 acttattgga aaaagaactg ttattatata ttctgtaact ttgacactgt cttcaataat
     7921 aattggatat ataacaaatt tacttttagt gaataataac tcagtaaatt tagatgcaac
     7981 aaattcttca atacagttgg caaataaact aatgttaaat atacctgata gttttgagta
     8041 tgtatgtact attttaatta ttttatttgc atttaaatca ataataccaa agatgaaaga
     8101 ggtcatagga aatcatgctt aaaaagatag ttataatatc ctgtatagta gttgtgttaa
     8161 tcattttatc aaaaatagtt gatgataaca tcaaagaaga tgcttctatt ccaaatgtga
     8221 ataaagaaac attagaatat tttagaaaaa attataaaga agacataata acttgtgctg
     8281 aagaagactt aaataatgat ggaaaaaaag atttagtagt tatatataaa aaaagcaata
     8341 attcaaatga aatggtagtc gtagtttctg ataaaaatag ccactatata acaaagccaa
     8401 taccagcacc tatagagaat caaacgataa cctttaaaaa tattgatgat aaagcaccaa
     8461 tagaagtaat tgtatcaggg tctaaaaatg gtaatgtagg atatgctatt tacagagtag
     8521 agggtaaaaa atttgttgat ttatttggcg aagatatgga caaatgttgc taaaaataaa
     8581 aataatacat aaaggtggga aatttatatg aaattatcta agaagattca agcattaatc
     8641 ttatttggtg taatgggtac atctatatta acaggatgta gtagtaaacc aaaagaaaaa
     8701 gaagaagcaa aaactggaaa agatgattat acaataacag taggttatta taattgtgac
     8761 catatgactg cgggaccagt agcagaatcg gcaggaatat ataaagattt aggtcttaat
     8821 gtaaaaactg ttggaaatgg taaagttcct gaagctatgg cagcaggaaa aatggatgca
     8881 ggttacatag gaactaaggg gttagttgga gcaataccta agggttcgcc aataacaata
     8941 gcagctaaca accatactgg tggttctgaa tatttaatag tttcaaaaga tataaaagaa
     9001 cctaaagatt taataggtaa aaaaattgca acagatatga gtgatttctt atggacaagt
     9061 gattatggtc cagaaacagg tctaccaact gacccatcaa aatatgaagt tgtaaatatg
     9121 gattcagaca aagataaata tttagctctt aaaactggga aaattcaagc ttttacatct
     9181 tgtgaccctt ggggttctgt agctgaaaat gacggtgcag gaaaaataat agcatctact
     9241 caatataaag aaaaagctaa tggcaaagaa tataactgtt gttcattctc attaaacaaa
     9301 aactttataa aagaacatcc agatttagca aaaaaattgg ttctagcaca tacaaaagca
     9361 atagaatata tatatacaaa tccagctgaa gcagctaaaa tatttgcaaa atattataat
     9421 gtagaagaag aagttgcact tagaactatc tataagaaga ctgttggaga aggtagaact
     9481 cttacttgga aagttacagg tgaagaatat aaaaataatt tacaaatgta taaagattta
     9541 aaggctttag atgatatacc taaatatgaa gatacgattg atacaagctt attggactct
     9601 tgtggagctg atgattttga caaatttata aaagaaaaag ttaacccaga gtttcctgaa
     9661 ggtatgagtt atgaagactg gaaagcaaag gtattataaa taaatggaga atatgaaaaa
     9721 tataataata ctttttatca ttattttggg aagtatattt ataatatttt ttaattttga
     9781 agataaagaa gaaataaaag gaaaattaag aataggggta tctgatgata cctctggttt
     9841 tgtaataaat tatatggtaa atagagacta ctttgaaaat ataaaagtaa gtgatataat
     9901 ggatattttt acaattaatg attgctgagc aagtacaatg cagtgggctc tgagttcaga
     9961 ggaaatagat atagcaatca tatgtaaaga tgctgcaaaa caatatgtaa atgtaaatag
    10021 tggatttgaa attgttggta ctgtagttca aaattctgat atatttctat taagtgataa
    10081 taatcctgaa aagataggag tcattcaaaa tagagattac cagtcagaat tggttaaaaa
    10141 atactacaag aatgtggaag tagctccctt attagggact gcactagcat atggattaga
    10201 aagtaattta gtagatggtg ttgtaataga ttgcataaag tcaattgggt tagagggtaa
    10261 aagaaaatct acaactaaat taggagatta tgatacctat gtattagttg taaataaaga
    10321 gtttaaaaaa agtaaagcat atagtgattt tataacactt tacaataaaa gtgttgatgc
    10381 tttaaagaat aaagctacat ttaagaaagt attaaaagag tacaggaata taagaaatat
    10441 agatatggag gaaataagca attggaaatt aaaatttcta aagataaaag cgatagatta
    10501 actaagaaaa aaactgatgg tagtatggat attttatata aaataatact attagttatt
    10561 atatttttag tctggcattt tgcagcaaaa gatataggga gttctttgtt acttccaatg
    10621 ccagtagatg taataaaagg tttctttttc tgtgtgacag atgcagagac agtcactaat
    10681 ctttttataa cattgcagag agtacttaaa ggttttatgt atgcattatt gtttgggctt
    10741 ccaataggat ttattatggg attttctaaa acttttgaaa gggttttatc tccagtagta
    10801 gattctgtaa ggcaagttcc aataatggca tgggttcctc ttactatagt atggtttggt
    10861 ataggagatg gtccaacaat atttttaata gctttttcag gggttttccc tataatttta
    10921 aatactattc aaggagtaag agcaatatca aaggattatt ataatgcagc tagaagtatg
    10981 ggagcatcgc caattgtgat atttacaaat gtaattgttc ccgcatctct tccagatata
    11041 ctaactggtt caaggattgc tataagtaca ggatggatgt ctgttatctg agccgagttt
    11101 atagctacga gtgccggtct cggttactca atggtacaag ctcaaacatt aatgcataca
    11161 gatgtattaa ttgggcttat gatatttgca gctttaatag gatttataat agatagggta
    11221 ttaaagttta taaataaaat cctttgtaga tggaggtttg cagattaatg aagttaagtg
    11281 taagagatat aaataagaca tttgtaaata atagagtaca tacaaaggtt ttagaagata
    11341 taagtatgga tatagatgat ggacaatttg tctgtctttt aggaccatca ggttgtggaa
    11401 aaacaacttt acttactata ataggtgggt ttcaaaaatc agaacgtgga gatgttttta
    11461 taaatgataa aagagttaaa aaaccgggca tagatagagc ttttatattt caaaattatg
    11521 ctttatttcc ttggaaaact ataagaggta atgttctatt tcctatgaaa cagcagaaaa
    11581 taccaaaaga aaaaagagaa gaaatgctag aagaactttt ggttatgtca gacttgaaag
    11641 gaaaagaaaa actgtttccg catcaattat ctggaggaat gaaacaaaga gtggccatga
    11701 taagagcttt agcatgtaat ccagaggtat tactaatgga tgaaccatta ggagctgtag
    11761 attttcaaat gagacaaaat ttacaggaag agctagaacg aatatggata aagaagaaaa
    11821 taactgcatt aatggtaact catgatgttg atgaagctgt atatatgagt gatagagtta
    11881 tagtaatgtc gagagataaa ggaagaatta ttgatgatat aaatatagat attccaagac
    11941 ctagaattag aggaagccaa aaatatgaag agtacaaaaa caaattaact gatactttat
    12001 caaagtgtta tgaagtttaa agaggagtag acatgagtca aatagaaaaa tacaatagtt
    12061 tggataatac acaacagaaa ataagaatct ctattatgga tatgataata gataaaggtt
    12121 ctagtgttac acttcaagaa gtgactgaat atgtaagtaa aaagttgaat atagaaaaag
    12181 aatatataga aaggacacta caatatttta tttataaaaa tataatggtt gttgatggga
    12241 atagtataaa ttttatatat cctgtatcag cattgccaac aaatcataaa gtaactttga
    12301 gagataatag aagtttcagt gcaatgtgtg ctatagatgc tataggaacc tcttgcacat
    12361 tcaaccaaga tataaaaata aactctattt gtagtgctac aggtaaggaa atagaagtaa
    12421 ttataaaaaa tgaaaagatt gagtatgtga ataatccaaa cttaagagtg cttcatataa
    12481 atcttgataa gcatctaaat tgggctgcta gttgctgaaa tataatgaat ttcttctgga
    12541 cgaagagtga ttttgatgct tggacaaacg aagcgggatt atctaatgat gaagatatat
    12601 attgtttaga tattaatgag gcaatagtag aatcatataa aatatttaaa ctcaaacaaa
    12661 aggtactatc atagatatac atatatgaaa aactaaaaat gacctttaga taaaaatgat
    12721 aggtaatatc catactatat aaattagtat agagtaggga tgtgaaaagt atttaaatct
    12781 aaaggtatat ttttagtttt tttagatgat tagatagcct tattaagtat atatttattt
    12841 ataacctttg caactccatt ttcattatta gtatcagtaa cataatctgc aatttccttt
    12901 atactattac gtgcattccc catagccaca ccaagacctg catactttat catatgttgg
    12961 tcattttctt catcgccaac agcaatagca ttttctatag gtatatttag attcgtacat
    13021 aatgttttaa gagcagttcc tttattagta gttttaccta aaaattctag ataaaaagga
    13081 gcagacctta ctatagtata tttattgaat aaatttttag gtagttgctg tatgatttct
    13141 tccaatcttt ctggttcatc aactatcata attttacaga ttttaataga ttcatcaatt
    13201 ttatcttttt gtatatattt gacttctata ttatttaatt tcgcttcatg aagtgtatat
    13261 ttgccaggcg tttcatttgg tgtaattaaa tttgtcattg tatttatgtg tattttagtc
    13321 ttatattttt tacaaacgtt attatatata aaatcaaaat catctaaagt catttctaca
    13381 tcatgtatga ttttctcact tttaacttct tgaataattg ctccattaaa gcatataaca
    13441 taatcacctt catctgttaa atttagttga tttagaagtt cttttacacc aggaagaggt
    13501 ctgcctgttg ttataactac ttttgcccca gccctttttg cctcctgaat ggactcaaag
    13561 acttcaggag taatcctttt ttgtgtattt aatattgttc catcaatgtc tagtgcgatt
    13621 aatttgtaca tatcaacctc caataaatta tatactcaaa tttcctgtga aaacgttgac
    13681 acagctagtg ttgaacaaag tttcagtggg aaatatggtt tgttttgtat actattatat
    13741 caagagataa gtaatttaga aagtttaata atattaattt tttgataaaa atattactta
    13801 tgtgagatga gaatgtaaaa actttgtaat caataattcc aaaattctta attacaaata
    13861 atggtatcgt ttgcattgtt aatataaata aatgtatatt atatagttag aagtttgaat
    13921 aaatagactg atggtaattt gttatattag ttagttttgt gttataaaat attgtaattc
    13981 cattaatcat atgttattat tcaacatgat tataatataa agaatatttg atatatataa
    14041 taatttataa aagagtatta catagtacat gtaaatctat atttataaat acaataaagt
    14101 aaagttgtaa aggagtgctt taaatgaagt tttcagagtt taagtatgaa agacccaatt
    14161 ataatagtat gaaaaaagag tttttgagtt gtgtagaaga tataaataat tctcgtaatt
    14221 ataaagagca acaaaaaaat atacataaga ttaatttatt aagaaataaa ctagaaacgt
    14281 tgtcaaatat agcttcgata agatatagta cagacacatt taataaattc tacaaagaag
    14341 aaaaaaatta ttgggatgaa tatatgcctt tgtatgaaga attaaattca tatttttata
    14401 atgccattgt aaattcaaaa tttaaatatg atttgataaa agagtttgga gagcaatttt
    14461 tcacaatagt agagtattct ttaaaaagtt tttccaaaga aataataagt gaattgcagg
    14521 aagaaaataa attgtgttca gagtatacta gacttttagc ttcagctgag ataatgtttg
    14581 atgggaaaat aagaaattta tctggtatgg ggaaattcat gtattctaag aatagaaaaa
    14641 caagagaatt agcaaacaaa gcatattata atttctttga agaaaatgaa actaaatttg
    14701 atgacatatt tgataaattg gttaaactta gagataagat gtctaaaaaa ttaggttttg
    14761 aagattttgt agagcttggg tatgttagaa tgatgagaag tgactacaga gaatatatga
    14821 taaaaaatgt tagaaaacaa gtattaaaat atgttgttcc aatggcaaat gagctttatg
    14881 aaaaacaagc taaaagaatt ggtctagaat atttaagtta catagatgaa ggcgtggaat
    14941 ttttaacagg aaatgcaagt ttaaagggag attcaagata cataattcaa aatggtaaaa
    15001 ggatgtattc tgaactgtca aaagaaacaa atgaattttt tgattttatg ttagaaaatg
    15061 aacttatgga tttagaaacg aagaaaggaa aaggagctgg agggtattgt acttatatac
    15121 cagattataa atcaccattc attttttcta attttaatca aactgctgat gatatagatg
    15181 tgttaacaca tgaggcagga catgcatttc agttgtatat gtctagatgg attgatatgc
    15241 cagaaattaa ttttccaacg cttgatagtt gtgaaatcca ttcaatgagt atggaattta
    15301 taacatggcc gtggatggat ttatttttta aagaagatac agataagtac aaattcactc
    15361 acttatcatc ttcaattaaa tttatacctt atggagtaat tgttgatgaa tttcaacact
    15421 atatttacaa aaatcctaat gtagataagt caaaacgaaa agaaatctgg agatttttag
    15481 agaaaaaata cttacctcat agaaaatatg gtgataattc ttttttagag agaggttgtt
    15541 ggtggtttaa acaaggacat atatttaaaa atccgtttta ttatatagat tatgtattag
    15601 ctcaaatttg tgcgttacaa ttttggaaaa aaatgattca agatagagat gcaggatgga
    15661 aagattatat aaatatctgt aaagttggag gaacaaaatc atttttagat attgtgagta
    15721 tgggaaattt gtattctcca tttgatgatg gctgtattga gtctattata ggtgatgtta
    15781 aatcttggtt tgatgaaata aatgacagca aattataaaa aattatgaga attttattgt
    15841 ataaaagtga aaaattaaaa actatataaa aagtgattat ttgttgtgaa aatagtcttg
    15901 tttttaacta aattgataaa ataaactaaa aaagatttgt acttaaaaaa aaaagaaaat
    15961 acaagaaata tgcaatatca acatttggaa aaaaaagtaa aaatgtatac aaaatacata
    16021 taaaaaaact attgcaaatt ttatagaatg tttatatact taagtcaaca gagatagaaa
    16081 aaagctattt atagaaaaca aaggataaat tgcttaattt taaattttct gaaaaaaata
    16141 ataatccgga tgaagagtat gggagactgc tttataaaaa gcgaccgaag ggacaagttt
    16201 aatcttactt acccaaaaga ttagatgaaa ttctcaggta aaggtgactg tatttggacg
    16261 gggctctgaa aatgatttta acagggaaga caaattggga gatttgtttt tcctgttttt
    16321 tatttatcaa gtaataaata aaagtttgaa agagagtaaa aaaatgataa taattacgaa
    16381 taatccaaaa gtaaaagaag aagttcaagg cagagaagtt ttgtttaaag acacaactta
    16441 tattggaatc ttagaagcaa gtagagattt gatacatgaa ggttatgaac ttttatctca
    16501 tccactctat gggagtgtaa agccaaatga aacaccttac aggactgtta tactaaagaa
    16561 aggaaatcgt ttggatataa actctttaac cttaattgaa gaagcaatca tcactgcaag
    16621 taaatttcag aataataaaa agactccaaa atggacagaa agtgttcaag atgattttag
    16681 agtaattgat tatgatatat tttataatac aatacaaaga atgcagtatg aataaaaaaa
    16741 tttgttaaaa agttattaaa acagcctaaa tattaaatct aatttaatat taaataaaat
    16801 gagaaattta attggggagg ataagtcaaa atggaaaatg tgtatgactt agtaataatt
    16861 ggttcaggac cagcagggct tgcagcaggt ctttatggag caagagcaaa gttaaaaact
    16921 ctaatcctag aaaaagacaa gactggtgga caaattgtaa taacacatga aattgcaaat
    16981 tatccagggt cagttccaaa tgcaacagga ccaagtttaa tagctagaat ggttgaacag
    17041 tgtaaagagt ttggagcaga aatgctaaga gacaacattg ttgatactga gctagatgga
    17101 gatataaaag ttttaaaagg ggaaaaggca gaatatagag caaaagcagt aataataggt
    17161 acaggagcaa caccaagaaa gattggttgt cctggagaaa aagaacttac tggtaaaggg
    17221 gtttcatatt gtgcaacttg tgatgcagat ttctttgaag attttgaagt atttgttgta
    17281 ggtggaggag acagtgcatt agaagaagca atgtatttaa ctaaatttgc tagaaaagta
    17341 acaattgtac atagaagaca aggatttaga tgtgctaaga gtgttgaaga aaaagcaaaa
    17401 gctaatccaa agatagagtt tttattagat acagtaattg aagaaatcaa aggtgatgga
    17461 atattagaat cagttgtatt taaaaataaa gttactggag aaactcatga atactttgca
    17521 gatgaagaag atggaacaat gggagtattt gtgttcgttg gattagatgc tcaaactgat
    17581 ttattcaaag gtaaagttga tatggatgaa aaaggttaca taataactga tgaagatatg
    17641 agaactaaca taccaggcgt atttgcagca ggagattgta gatctaagac tctaagacag
    17701 gttgtaactg caactaatga tggagcaatt gcatctatag tagctgagaa atacattgat
    17761 gaaaaatttg ggaactagaa tctgtaaatt aagaaatagt gtctgtaaat ttaatgaata
    17821 atatttaaaa ttaaaataaa aatttcaagg gggaataaga aaatgttaga tttagataag
    17881 gctacatttg aagaagaagt tttaaatgca gaaggttttg tatttgttga tttttggagt
    17941 gaaggttgtg agccttgtaa agctttaatg ccagatgttc ataaattagc tgagacttat
    18001 ggggataaaa taaaattctg taagatggat acaacaaaag ctagaagatt agctataaaa
    18061 caaaaagtat taggtcttcc aactatggct atatacaaag atggagaaaa agtagacgaa
    18121 gttactaagg atgatgctac agttcctaat atagaaagca tgattaaaaa atatctttaa
    18181 tatgttgata aattattaac attaaaagaa aaaatctatt tttatctgaa gataagaaga
    18241 aaaaggtttt tatgtccaac tttgttaaaa aaataatttt aaataaaata atttttttac
    18301 aataaatatt ttttagtaat aaaataaaga tttaaggcat aaaaacacaa taatatatct
    18361 ttaaaaaaat aagataaatt gtaaaatgat ataattttga gaaaaactca aatgcatata
    18421 cacaaattaa ataacaggag gtgcaagtat gcgtcttgaa ttagggaaaa tctttataaa
    18481 agatattcaa tttggtgatg taacagaagt aaaagatgga gtattattca tcaataagca
    18541 agagatgcta caagaaattg gtggagatga gcatattaaa tctatagata tagaattagc
    18601 tcgtccaggt gaaagcgtaa gaataacacc tgtaaaagat gttattgagc caagagtaaa
    18661 agttgaaggt aatgggggaa tcttccctgg tatcatgtct aaagttgaca ctgtaggaga
    18721 aggaaaaact catgctttaa aaggtgtagc tgttgtaact actggaaaaa tagtaggttt
    18781 ccaagaaggt ataatagaca tgactggaga aggagctaag tatactccat tttctaaatt
    18841 aaataatgta gtagtaatag ctgaacctat tgatggttta aaacaatacg ctcatgaaaa
    18901 agctgttaga atgataggat tcaaagcagc aatgtactta ggagaagtag caagaaatct
    18961 tactccagat gaagtttcag tatatgaaac taaacctctt cttgaatcaa taaaagaata
    19021 tccagagctt ccaaaagtag gatatgttta catgcttcag actcaaggtt tattacatga
    19081 tacttatgta tatggagtag atgcaaaaca aatagtacca actttattat atccaacaga
    19141 attaatggac ggagcaattg taagtggtaa ctgtgtttct gcatgtgaca aaaacccaag
    19201 ttatgttcat ataaacaatg gggttgttga agacttatat gcaagacatg gtaaagatat
    19261 aaactttgta ggtgtaatta taactaatga aaatgtttat ctagcagata aagaaagatc
    19321 ttcaaactgg acttctaaat tatgtaaata tttaggatta gatgcagtta tagtttcaca
    19381 agaaggtttt ggaaatcctg atactgacct tataatgaac tgtaagaaga tagaaatgca
    19441 aggtgttaaa acagttatag ttacagatga atatgctgga cgtgatggag gttctcaatc
    19501 acttgcagat gcagatgtaa gagctgatgc tgttgtaaca ggtggaaatg ccaaccaagt
    19561 tgtagttctt cctaagttag ataaagttat tggacattta gaagtagtag atgtaatagc
    19621 tggtggttct gatggaagtt taagagctga tggaactatt gaagttgaaa tccaagctat
    19681 aacaggtgca actaatgaaa caggatttgg tcatttaact gctaaaggat attaagaagt
    19741 attttattaa acgattgagt aatgttaata aaacatatta tagataatta taataagtgt
    19801 tatagatata taaaaatata ttagaaatat aataaggagg attattatga gtttacttag
    19861 taataaaaag gttcttataa taggtgaccg tgatggtata ccaggacctg cgatagaaga
    19921 atgtgtaaaa acagtagaag gagcagaggt tgttttctca tctacagaat gctttgtctg
    19981 aacagctgct ggggctatgg acttagaaaa tcaaaacaga gttaaagatg ctgctgataa
    20041 attcggagct gaaaatgttg tgattttact aggtgctgct gaagccgaag ctgcaggtct
    20101 tgcagccgaa acagtaactg ctggagatcc aactttcgct ggaccacttg ctggagttgc
    20161 cttaggatta agtgtttacc acgttgttga ggaaccaata aaatcattat ttgatgaaag
    20221 tgtatatgaa gaccaaataa gtatgatgga aatggtttta gaagttgaag aaatagaaga
    20281 agaaatgtct ggtataagag aagaattttg taaattttaa tgcctaaaag caaaaggggt
    20341 gaaactaaga gatgggaaaa ctaaaagcag tacattatat taatcagttc tttgctggta
    20401 taggtggaga agaaaaagct gatactaagc cacatgtggc agaaacttta cctccaataa
    20461 gtttacaact tgataaatta ttaggtgaag atattgaaat agttggaaca gtagtttgtg
    20521 gagatagcta tttcaatgaa aatatagata gtgcaagtga agaagtttta tcaatggtaa
    20581 aaggttttga accacaactt ttcatagctg gtcctgcatt taatgctggt agatatgggg
    20641 ttgctgctgg aacaataact aaagttgtaa aagatgcttt gaatatacca gctttaacag
    20701 gtatgtatgt tgaaaatcca ggagcagata tgttcaaaaa ggatgtttat gtagtagaaa
    20761 cttctgattc tgcagcaggt atgagaaagg cacttcctaa gatagctaaa cttgcagtaa
    20821 aacttgctaa tggagaagaa attggaactc ctaaagatga aggatacata gctagaggaa
    20881 taagagttaa ctacttccat gaagacagag gttctaagag agctgttgac atgttagtta
    20941 agaaaataaa aggtgaacca tttgaaactg aatacccaat gccaaacttt gatagagttg
    21001 acccaagtaa agctgtaaaa gatttatcaa aatgtaaaat agctttagtt acttctggtg
    21061 gtatagttcc aaaaggaaat ccagatagaa tagagtcttc ttcagcttct aaatatggaa
    21121 cttattctat agcaggagtt atggatttaa cagaagagac ttatgaaact gcacatggtg
    21181 gatatgaccc agtgtatgca aatttagatg cagatagagt attacctgtt gatgttctta
    21241 gagatttaga aaaagaaggt gtaattggaa aattacatga gactttctat acaactgtag
    21301 gtaatggtac atctgttgca aactctaaaa aatatgcttc tgaaattgga gcagcattag
    21361 tggctgatgg tgtagatgca gtaatattaa cttctacatg aggaacttgt actcgttgcg
    21421 gtgcaacgat ggtaaaagaa atagaaaaaa ctggacttcc agtagttcat atgtgtacag
    21481 tagtacctat ttcattaaca gtaggggcta atagaatagt tccaactata gcaatacctc
    21541 atccacttgg aaatccagcg cttgacccta cagaagaaaa agccctaaga agaggccttg
    21601 tagaaaaagc attaaatgct ttaactacag aagtagatgg tcaaacagta tttgaaaaat
    21661 aaaaataaca cacacatata ttatatagat aaaaatataa acacacacta aaaataaaaa
    21721 ataactatac acaaaaaaaa taatatagat ttcatgaatg gataaattgg agttattcat
    21781 tcatgaaatc ttaaaaaatg ccaaaataca taaacaataa tagaatcaaa tatacaataa
    21841 aatacaatga ttagagcttt taataagttt aataagatta aaaaataagt gttcataaaa
    21901 tttatggagg tgcacaaaat gacttatcca gttttaaaag gggcaggcta tgtacttatt
    21961 catactccag atatgatagt gcaaaatgga agtacttgta cagttgaaag agcaacaaat
    22021 ccagattcag aatttttaaa agaagtaagt aatcatataa gaagttatga agatgtagtt
    22081 aactacatgc caaatcaagt ttatatagga aatagaagac cagaagaatt aagagattta
    22141 ccaatgccat ggtgtgaaca aaagattgag ggaactagaa atggtaagtt tggagaaata
    22201 atgcctcaag atgagttcat agctttaatg caaataagtg atgcatttga tttagtaaaa
    22261 ttatcacaag aatttattga tgaagtaaag ccaaaaatcg aaaataacta ccctgaaatt
    22321 gcaccttttg taggtaaatt aaagggtgat gatatagaag aaggtaaaga attagtagca
    22381 acacacatag ctgaaggatt ataccatgat ggaaaatttg ttggttatgt aaaaagagca
    22441 catgatgtag atgttaactt aaatgcccat acaatgtttg aaaatctagt agtaaaagca
    22501 tctggagttt tatctgctat tcaaatgcta agacatagca aaatagaccc tgctgaaata
    22561 gattatgtta ttgagtgttc agaagaagct tgtggagata taaaccaaag aggtggagga
    22621 aactttgcta aatcaatagc tgagatagca ggacttcaga atgcaactgg ttctgacaca
    22681 agaggatttt gtgcagcacc aactcatgca ttaattcaag cagcagcttt agtaaaagct
    22741 ggcatacata aaaatgtaat ggtagtagca ggtggagcaa gtgctaaact tggaatgaat
    22801 gctaaagacc atgttaaaaa aggtcttcct gtacttgaag atgttgttgg aggatttgca
    22861 gtacttgtat ctgaaaatga tggtgtaaat ccagttataa gaactgattt aacaggtaag
    22921 catactgttg gaactggttc ttcaccacaa gcagttatga cagcacttat aacttcaggt
    22981 cttgatagag ctaatttaaa aataacagat gttgatgtgt attcagttga aatgcaaaac
    23041 ccagatataa ctaagccagc aggagcagga gatgttccag aagcaaacta caaaatgata
    23101 ggggcacttg ctgttaaacg tggagactta gaaaagaaag aattgaaaga ttttgtttct
    23161 aacaaaggat taccaggatg ggcaccaact caaggacata taccatcagg agctccttat
    23221 ataggatttt taatagatga tttaactaca ggaaatagaa atagagctat gatagttgga
    23281 aaaggtagtt tattcttagg aagaatgact aacttatttg atggagtatc ttttatagct
    23341 gaaagaaata caggtgttac tgaagagact tcaggaatat ctaaggatga aattaagaag
    23401 ataatagctg aatctatgaa aaaactagca ttagatatgt tagaagaata ggggtgagga
    23461 tatgtcaaaa aaagtaatcg cagatgtatt cttagaagta gctaatgcaa tagaaagcgg
    23521 cgaatttggc aaaaaagtaa aaattggtgt tactacactt ggaagtgaac atggtgtaga
    23581 aaacatggtt aatggtgcac aattagcaaa atctaattta tttgatattg tgcttattgg
    23641 accaaaagtg gaaactgacc ttgaagtagt tgaagttaat gatgaaaaag aaatgcatgc
    23701 aaaaatggaa gaattattag attcaggata tattgatgct tgtgttacta tgcattataa
    23761 ttttccaata ggtgtatcta cagtaggtag agtaataact ccagcaaaag gaaaagaaat
    23821 gatacttgca acaacaacag gaacaagtgc tactaataga atagaggcaa tggtaagaaa
    23881 tgccatttat ggtattgcta cagctaaatc aatgggtaac aaatgcccaa aagttggaat
    23941 acttaatgtt gatggagcaa gacaagttga gaagtgctta aaagaattaa aagataatgg
    24001 atatgacatg gagtttgcgg attcaattag agcagatggt ggatgtgtaa tgagaggtaa
    24061 tgatttactt gtaggtgcac ctgatgttat ggttactgat acattatctg gaaatatatt
    24121 tatgaaagta ttttcttcat atactacagg tggagattat gaagctcaag gctttggata
    24181 cggacctgga gttggagaag actatgatag aaaggtactt atagtatcaa gagcatcagg
    24241 ttctccggta gtagcaaatg ctttaaaata cgcttatgat gttgtaaagg gagatataag
    24301 taatgttgca agaaatgaat ttgcaaaggt taaaaaagca aaatttgatg acattatatc
    24361 ctctcttact aaaaaagaag ttaaagctga aaaagtagaa gttaaaatgc cagataaaga
    24421 aattgttact cgtcaaatag ctggtgttga tataatggat ttagaagatg cagtatctga
    24481 gttatggaaa aacggaatct atgctgaaag tggtatgggt tgtacaggtc caatagtttt
    24541 agtaaatgaa gctaaaggag acttagcagt tgaaacttta gttaaagctg gatatactgc
    24601 aaaataagta cattttttat atgtaaataa gaacatatag ttataatttt attgattata
    24661 attatatgtt ctttttattt tatatcttgt caatatttat atattaacac aatccattta
    24721 tttgattctc tagctaattt attatattta ttcaattaaa attaagcttt ctaactaaat
    24781 aaaaactaat gaagtattaa aatgaaatta ataaaatatg aaaaaatttt aggaataaag
    24841 tatctgttag ataaaaataa gattaattag tgatataata taattaagat aaaatttatt
    24901 atttggaggt aaaatcatga gcagagtaaa aaatgtagta gaattgttgg gaactaaagg
    24961 tgttgatgca ctatatctaa caaagaaaac taatgtaaac tatataagtg gttttcctga
    25021 tgaagaagca tatgcagtga tttgcaaaga tggaaacttt ttagttactg atagtagata
    25081 tatggagctt gcagaaaagg tttgcaaaga ttttgaaatt ataaattggc ataattttga
    25141 tagaagtgtg gcaaaggcag ttaaaagtgt atgtgataaa gtgggtataa agaaacttgg
    25201 gtttgaaaga actaatatag tgtttgataa atatgaagaa cttaaaaatc tgattgagaa
    25261 ggataatgga gaattaatac ctacagaaaa tattgtagag actttgagat atgtaaaaga
    25321 caaagatgaa atcaaaaata caagaaaagc ttgtgaaata gcggataagg cattagaaga
    25381 attgattcca catataaaag ctggagttag cgaaattgaa ctggctacaa agttagagta
    25441 ctttatgaaa atgaacggag cacaaaatat agggtttgaa actatactga tatcaggagc
    25501 aaagacttca ttgcttcatg gtaagcctag tgataagatt atagaaaaag gtgattttgt
    25561 acttatagac tatggtgcta tgtataatgg ctatatatct gatacaacta gaacttttat
    25621 agttggagga gcttctgaaa agcaattaga aatatataat ttagttaagg aagctcaaaa
    25681 tgtaggggtt gagaacatga aagctggtgt acatgcgaca attccagatg ctgagataag
    25741 aaaagttgtc aaaaaatatg aagactatta ctatcaaggt ataggacatg gagtcggtag
    25801 ggatgttcat gaagaacctt tcattggtaa ttatggtgat aaaatcatag aagagggatg
    25861 tataataaca atggaaccag gtatttattt ccctggatgg ggtggagtta gaatagaaga
    25921 tactgttttg attactaaaa atggtccaga aagacttact aaattcccta aagatttgat
    25981 gattttagac aaataattta atttatatat atttttttac ataaaatata acataatctc
    26041 actattaagc tctatttaca tattatagta aagagggctt aattttattg taagaggtga
    26101 tagtatatat gtataaaaaa cataaattta taaaaaatat aaaaaaagcc tggtataaaa
    26161 tcaaattaat tgatagatgc cttataattg taatggcaat attaatgttt caatctatat
    26221 ataatttatt tgttaatgaa gtaaattcac aagatactac aactattgat gtagtagtaa
    26281 gaaccacttc agcagctata tttgggtatt ttttaagtgc taattttata aagagacctt
    26341 taaggaagta tacaaatact gatgtatctt caaatctttt tatagataat aatttacccc
    26401 caaaaggtca agagtctagt caaaataata taatgaatgt caaaaatacc attggattta
    26461 cttcagaagc tgataattat gaaaagaaaa tacctattaa taataatgaa ggttttgaag
    26521 aaggagaaac tagtgaattg caaattatta tagctactgt aatttgtata gcagcattaa
    26581 cagtactttt tgttgtaaga aattttacaa ctacaacatc agcttcttta ggtactattt
    26641 cacagatgag agattttgtc tcaggatgcg tgggtttttt gctaggttgt ccaagtaaac
    26701 ctgattaaaa aagtattatc aataaaaggt attttaaaaa gtatcagtat aataatattt
    26761 agatttaaat gtatacaatt ataattctat aacattctat attgtatttt tatactgata
    26821 ctctaaacta tactatttat taaaatattt taacattgta tttaaacaaa atattatatc
    26881 tgtataatat aaatttagtt tatatgaata gatgccatat actcaataaa aagtttcata
    26941 ctatgagata tgtattgatt tcttctccaa agaactccaa tatttgcagt aattgcacgt
    27001 tctaatggta ttgaacagag attttctgta ttttgaaata tttctttata caatattgtt
    27061 gaagccaagt cattttctag taaataacgt atggtagaaa gttgatttga gtgtaaaatt
    27121 atatttggct tagctttttc aagtcttttt gtaataatct tatagtgata agaaccttca
    27181 gataagatta caaaaggtac attttttaac atataatttg atataatggg atgttttgcc
    27241 aattcatttt tgggatttgt aactaagtac aattctgttt tatagattgt ctttgaatct
    27301 atatcatcat aaatatcact gtcaattata ccaatacaaa aatcaagtgt agattcttca
    27361 atcattttag ctccaacaaa tgttggaact tcaaaaattt taagctctat atctggataa
    27421 attacattaa atctaggaag tatttttgaa agcaaaaacg tacctaaaac tgtaggaata
    27481 cctattttga gagaagcttt tctctttttt cctaaatcaa gtgcgtcaca ttgaaaatcc
    27541 tcaaattgtt ttataaaatg ttttgacttg tctaaaaaaa tttttccttc aggcgttaat
    27601 tctattttat tacctattct gtaaaaaagt tcaaagccaa gttctttttc taattcttta
    27661 attgctaatg ttatggatgg ttgagaaata tgaatacttt ccgcagcctt agtcatgttt
    27721 ttatatttac agacagtttg aaaatagtat aaatagttta tattcatttg gtattagttc
    27781 ctttcattta catattagtg acaagtatat aattaacaat agcataagtt ttgtatattg
    27841 ttgtaaaaaa atagaatagt tttaaactat catagcataa gtttttgata ttttcaatct
    27901 attaagaata gtgctattat taaattaaca aaagagaata gctggtatgg tttagagtaa
    27961 atcaatctat attacagtta tatcaacgaa tatcaaaaaa ttatctatta gaaaataaaa
    28021 attattttta caattaaatt gttaattaaa tcataaagaa aaaagtgata ttaacaagat
    28081 aaaatttttt taatcagaaa tgttaattta ataacaaaat agagtattgg ggagaaagga
    28141 gaaatatatt ttttaataat atttgttaat ttaataacga aaaatgaaag ggagtgattt
    28201 agtgaagttt gaattgatgg attttttaat gaatcctttt gtccttatgt ttgctgcagt
    28261 aattacagga attttatttg gaaaaattaa atttgggaag tttaattttg gggtatcagg
    28321 agcattattt acaggattat ttattggatg gcttgcatat agcttgggga atctaataat
    28381 agcaaaagga gaaacagcag caggatataa ggcagcaact gtaatgatgg ggaatggaat
    28441 tatttcttct gacttctttg atttcttttt aataatattt gttgcagcag ttggtctatt
    28501 ggcagcaaaa gatatgaaag ctgtattaaa gaagtatgga gcaagatttg taattttagg
    28561 agttcttata acttttatag gtggctctat gacttatgca atgactttac tatcaagtga
    28621 taaaggaagt agtgcttatg aagtttctgg cgtttacaca ggagcattaa caagttcgcc
    28681 tggattagct gctgctttag aaacagctgg taaacatgca gaagatgtat caaaagaatt
    28741 tgaaaaagct tcaataaaag ataaaaaaga aattttaaaa gtagtcgacc cagaaggcaa
    28801 attggatgtg aatacaacta catcactgac tcaagagcaa atagataagt atattgcata
    28861 tgctgaagct ggtgttggta taggtcatgc agtcgcatat ccttttggag ttttaatagt
    28921 aatcttaggt gtaaatttcc ttccaaaatt atttaggatg gacctaaaag aagaaagaag
    28981 aaaatatgag aaggaaatga aggaagcaag agatagtgtt tctggtaaaa cgataccaga
    29041 agttccattt aatataataa catttttctt gacatgttta gctggatact tagttggagg
    29101 aatacatgta tttatgggac cactagggta cttcacacta ggcgcaacag gaggttcact
    29161 aattgtatct ctagttcttg gatatatagg taagataggg gtagtaaatt tcagaatgga
    29221 agaaaaggtt ttaaatattt taaaacaaat agggctagta tttttcttag caatagttgg
    29281 attaagatat ggtggaaaag tagttgattc aattatgaca tctggtatgc acctagcctt
    29341 agtagcaata gcagtaggtg ttacagctat gatgatagga ttcttagttg gcaaatacgt
    29401 atttaaatta aattggattt tattatctgg agctgtctgt ggtggtatga catcaacacc
    29461 aggtcttgga gctgctgttg atgctcttga tagtgatgac ccagcagcag gttatggtgc
    29521 tacgtatcca tttgcattat taactaaagt tatattggtt atagttttac acaaacttcc
    29581 aatgtaaata agattttata tggggggata tttatgaata atgaaggagc atttgaagaa
    29641 ttaagtggaa gattaagaaa taaagaattg tgtgatttaa taatgaatgc agatgaagct
    29701 gctaaaatta tagaggatgg catggttatt ggagttagtg gatttacacc ttcaggctat
    29761 ccaaaagtag taccattagc agtttcagaa agagctaaaa gtggagaaaa gataaaatta
    29821 accgtatatt caggagcatc tttaggccca gaagttgatg gagcatggtc agaagcaggt
    29881 ataattgaaa gaagacttcc ttatcaaact aattcaatac ttagaaataa tattaataaa
    29941 ggtgttgttg attatataga tatgcaccta agtcattcta ctcaattttt aaattatgga
    30001 actataccta aagtagatgt agctatagta gaagcacttg caataactga agaagggaat
    30061 attataccaa ctagtgggat aggtaattct ccatctttta taaaaagtgc agataaagta
    30121 atagtagaga taaatcttgc aaaaccaatg gaaatggaag gtatggcaga tatatatatt
    30181 acggaaaatc caccaaatag aaaaccaata gaaataaatc atcctaagga tagaattgga
    30241 acaacatata taccttgtgg tttggataaa attgcaggag tagtaattac caatatgcaa
    30301 gataagaccc gtccattggg ggttgtagat gaagcttcga aaaaaatatc aaataatatt
    30361 attgcttttt taagagaaga agtaaaggca ggcagattat caaagaattt acttcctctt
    30421 caatctggtg taggaagtgt agcaaatgca gtattatatg gattatgtga atctgaattt
    30481 gaaaatttaa cttgttatac agaggttgta caggactcta tgttggattt aataagaatg
    30541 ggtaaagtta caatggcatc tactacatct gtaagtccat ctccagaagg attaataaaa
    30601 tttgaaaaag atattgattt ttttaaggat aagattatat taagacctca agaaattagt
    30661 aacaatccag aaatagccag aagaattggt gtaattgcaa tgaacactgc aattgaagtt
    30721 gatatttatg gaaatgtaaa ttctactcac ataatggggt caaagatgat gaatggaatt
    30781 ggaggttctg gtgattttgc tagaaatgga gcaataacta tatttagtac tgagtcgatt
    30841 gcaaaaaatg gtgatatatc atcaatagta cctatggtat ctcacgtaga ccacactgaa
    30901 catgatgtaa tggtaattgt aacagaacaa ggatatgctg atttaagagg tcttgcacct
    30961 agagaaagag ctataaaaat aatagaaaat tgtgcccatc cagattataa agaacaactt
    31021 agggattatt taaatagagc ttgtaaaagt ggagcaaaac aaacacctca catattggac
    31081 gaagctttat catggcatag taaatttatg agtacaggta caatgaaaaa ggctgaaact
    31141 tttaaaagtg cattataaaa tatttaataa attggaggta gattttaaat ggaaaaagca
    31201 gtggaaaact ttgaagattt aagtaaggaa tacattaatg gttatattga gagagcaaga
    31261 aaagctcaaa gagagtttga atgttatact caagaacaag tagataaaat agtaaaaata
    31321 gttggaaaag tagtgtatta taatgctgaa tatttagcta aacttgctgt agaagagact
    31381 ggaatgggag tatatgaaga taaggtagct aaaaataaaa gcaaagcaaa agttatatat
    31441 aacaatttaa aagataaaaa atcagttggt ataattgata tagatagaga aactggaata
    31501 acaaaggtag ctaaaccagt tggagtagta gcggcaataa ctccttgtac aaatccaatc
    31561 gttacaccta tgagcaatgc aatgtttgca cttaagggaa gaaatgcaat tattatcaca
    31621 cctcatcata aagcaattgg atgtagtaca aaaactgtag agatgattaa tgaagaatta
    31681 gaaaaaatag gagctccaga aaatttaata caaatacttg accaacaatc aagagaaaat
    31741 acaagaaatt taatttcatc agcagatgta gtaattgcca ctggaggaat gggaatggta
    31801 aaagctgcgt actcaagtgg aaaaccagca cttggtgtag gggcaggaaa tgttcaatgt
    31861 atcatagata gagatgtaga cattaaagaa gcagtaccta aaatcatagc aggaagaatt
    31921 tttgataatg gtatcatttg ttcaggtgaa cagtcagtaa tagtagcaga agaaatgttt
    31981 gataaaataa tggatgaatt taaaaataac aaaggtttta tagttagaga taaagtacaa
    32041 aaagaagctt tcagaaatgc tatgtttgta aataaatcta tgaataaaga tgcagtaggt
    32101 caatcagttc atacaattgc aaaaattgca ggtgttgaga taccagaaga tacaaaaata
    32161 atagtaatag aagctgatgg accaggagaa gaggatatta ttgcaaaaga aaaaatgtgt
    32221 ccagttatat ctgcatacaa gtataaaagt tttgaagaag gtgtagctat tgcaaaagca
    32281 aatttaaatg tagaaggaaa aggacatagt gtatctatac attcaaatac agttaaaaat
    32341 atagaatatg caggagaaaa tatagaagta tcaagatttg ttattaatca atgttgtgct
    32401 actagtgctg gaggaagttt ctttaatggt cttgcaccta ctaatactct aggttgtggt
    32461 tcttggggaa ataacagcat ctctgaaaat cttgattata agcatctaat taatatttct
    32521 agaattgctt attatatgcc agaaaatgaa gtccctacag atgaagaact ttggggataa
    32581 aacttagaca aaaaatattc attctaaatt aaagtaggaa tatattttaa tttagaatga
    32641 atttaagaca taaattaaat ttaaattagt ttattggact aaatttaaaa tattaagaga
    32701 catatagaag aaggaagtat tataatttaa aataaataaa aaaatctata aaagagaagg
    32761 agtggtttta ttatggcatt aatgacagga gctcaatata ttgaaagttt gagaaaatta
    32821 aatactaagg tttatatgtt tggtgaagag gttaagaatt gggttgacca tcctatgatt
    32881 agaccatcta taaattgtgt agcagcaact tatgacttag ctcatgaccc agaatatgca
    32941 gatttaatga cagttacttc aaatatcaca ggtgaaaaaa taaatagatt tggtcatctt
    33001 catcaaagtg ttgatgattt gataaaaaaa gtaaaaatgc aaagactatg tggtcaaaaa
    33061 acagcttctt gtttccaaag atgtgttggt atggatgcgt ttaatgcagt gtattcaaca
    33121 acatttgagt gtgataaagc ccatggaact aattatcatg ataattttgt aaaatactta
    33181 acttatatac aagaaaacga tttagtagtt gatggagcta tgactgaccc taagggagat
    33241 agaagtctat cacctagtgc tcaacctgac ccagatatgt tccttcatat agtagaaaga
    33301 agagaagatg ggataattgt aagaggagca aaggcacatc aaactggttc aataaattca
    33361 catgagcacc ttataatgcc tactataagt atgactgaag cagataaaga ctacgctgta
    33421 tcatttgcag ttccttcaga tgctgaagga gtgtttatga tttatggaag acaatcttgt
    33481 gacactagaa aattagaaga aggtgcagat gttgatttag gaaataagga gtttggaggt
    33541 caagaagctt tagtagtatt tgataatgta tttgttccaa atgatagaat tttcttatgt
    33601 ggagaatggg atttctctgg tatgttagta gagagatttg caggatacca tagacaaagt
    33661 tatggtggat gtaaagtagg agtaggtgat gtaataatag gagcagcagc tttagcagct
    33721 gattataatg gagcaaacaa agcttcacat ataaaagata aactaataga aatgactcac
    33781 cttaatgaaa gcttatattg ctgtggtata gcatgttcat cagaaggtca caaaacagaa
    33841 gctggaaact atcaaataga tttacttctt gcaaatgtgt gtaaacaaaa tgtaactaga
    33901 tttccttatg aaatagtaag acttgcagaa gatatagctg gagggcttat ggttactatg
    33961 ccttcagaaa aagactttaa atcagatctt aaagttggaa caagtggaat gactattggc
    34021 gaagtatgta acaagtattt taaagcttct tcagtggttt caacagaaga aagaatgaga
    34081 atattaagat tcttagaaaa tatatgtctt ggttcatctg ctgttggtta tagaactgag
    34141 tcaatgcatg gggcaggttc accacaagct caaagaataa tgatttcaag acaaggaaac
    34201 ataaatcaaa agaaagaatt agctaagaaa attgcgggaa taaaaaaaga ggaagcttta
    34261 aatttataaa aagttgatat ataaagggaa attatatatt aatgtgtatt aattaatgaa
    34321 aagatatgta gtataagaga tagttataaa attatggtgg tttttagcta agtaaagaaa
    34381 tttttaataa ggagaattta cacatgacct gtggagttag attttgtggg ggctgtaacc
    34441 ctagatacga aagagggaag gctcttacaa taatcaaaga gcacttcaat ggtagggtag
    34501 attttagcat agcacaagag aacgtcgagt atgatttgct acttataatt ggaggatgcg
    34561 caactctatg cgcatcctat caacaatata aagtgaaaaa tgaatgtgtt aagatgtggg
    34621 attttagcca tatagaaaga gttataaatg tgattgaatc agcgatttgt gaaacttaaa
    34681 aaagctaaat ggggggattt cattgagttg gcaagaattg tatcaaagta aattatgtag
    34741 tgctacagaa gctgtaaaac agattaaaaa cggtgatact gtagtatttg cacattgtgt
    34801 aggtgaacct cctgcactag tagaggctat gattgaaaat gctgaacaat ataaagatgt
    34861 tgagattaaa catatggtaa gcttgggtag tggtggatat actgctaagg gaatggaagc
    34921 tcattttaga gtaaatccaa tgtttgtaag tggaaatgta agaaaggcaa ttgaaaatgg
    34981 agatggtgat tttacacctg cattcttcca tgaagtacca aagttgctta gagaaaaaag
    35041 attaaaatgt gatgttgttt tagcacaggt aactccacca gatgaacatg ggtattgtag
    35101 cttaggaaca tcagttgatt atacttatga agccattaaa actgctagaa cagtaattgt
    35161 tcaagtgaat gaccagtttc ctagaaccta tggtgaggta gtccatgtat cagagtttga
    35221 ctatatagtg gaaaaatcac aacctttatt tgaactacaa cctgcaaaga ttggagaagt
    35281 agaagaagca attggtaaaa attgtgcttc attaattgaa gatggttcta ctttacagct
    35341 aggtattggt gggataccag atgcagttat gttattttta actgataaaa aggatttagg
    35401 gattcattca gaaatgattt cagatgggac tttggccctt tatgaaaaag gtgttataaa
    35461 tggtaaatat aaaaattttg ataaagaaaa aatgacagtt accttcttaa tgggtactaa
    35521 aaaattatat gactttgcaa ataataaccc tgcagtagag gtaaaaccag tagactatgt
    35581 gaatcatcca gcaattataa tgaaacaaca taagatggtt tctataaatt ctgctataca
    35641 agttgattta atgggacagg tagttgcaga ggctatggga cttagacaat ttagtggtgt
    35701 tggaggtcaa gttgacttta tacgtggagt gtctatgggg gaagatggaa aggcaattat
    35761 agctatgcct tcaataacta caaaaaaaga tggtacagta atttcaaaaa tcgtatctat
    35821 tgtggatgaa ggtgcaccta taacgacatc aagaaatgat gttgactata ttgtaacaga
    35881 atacggtata gcagaattaa aaggaaaatc tcttagagaa agagcaagaa atttaataaa
    35941 tatagctcat ccaagtgtaa gagaaagtct agcagtagaa tttgaaaaga gatttaagga
    36001 gaaatattaa taatagaggg gtgttaataa tggaagcact tagagtagtt ccaaagatat
    36061 tttattttga tacatttaaa gaatttaatg aagaatttaa aataggaaaa aatgatttag
    36121 taattactaa tgagtttata tatgagccat atatgaaacc tcttggaata gatacaaatt
    36181 taatttttca agaaaagttt ggaacaggtg aaccatctga tgaaatgata gactccatga
    36241 caaaggaaat gaagaaatac aattttgata gaattattgc gtttggagga ggaacaatag
    36301 ttgatatatg taagatatta gcacttgatg ttccagaaaa gtctattgat ttatttgaag
    36361 gagaagtatc acctaaaaaa gtaaaagagt tagtagtagt tcctacaaca tgtggtacag
    36421 gtagtgaagt aacaaatgta gctattgcag agttaaaatc taaacatact aaaaaggggc
    36481 ttgcagtaga agaaacatat gcagactatg cagtgttaat tccagagaca gtaaaagggt
    36541 taccttacaa attctttgtt acaagttcgg tagatgctct tatacatgct attgagtctt
    36601 atctttctcc aaaagcaagt ccatttacag agatgtattc tctacaagca ataaaaatga
    36661 ttatggatgg gtataagaag atagttgata aaggagaaga agagagattt aatcatctta
    36721 gagactttgt tcttgcatca aattatgcag gaattgcttt tggaaatgct ggttgtgcag
    36781 cagttcatgc actatcttat tcaataggtg gagctttcca tgttgcacat ggtgaagcaa
    36841 attatcagtt ctttactgaa gtatttaaga tgtattctag aaaaaaacct aatggaaaaa
    36901 ttataaaatg tacaaaaatt ttagcagatg cccttgaatg tgaccctaac tgtgatgttt
    36961 atggagaatt agaaaagttt ttaaataaat taatagctaa aaaagctttg agagaatatg
    37021 gaatggtgga aagtcagata gatgaattta cagatagtac aatagcaaat caacaacgac
    37081 tacttgctaa taattatgta gagcttagta gagaggaaat aagagagata tttgcaaatc
    37141 tttattaata caatttttta tttatatgta tagtcaacat aaacaatgct aattatattt
    37201 atgtacaaat aaaaataagg gaacttaaat tttaattaaa gttaagttct cttattttta
    37261 tatggagtta aatataagta tatttttaat ttaaaatatg cttatattta agtctattac
    37321 tttatttgaa acaatttgta gaatttcaaa ttccttgaca gtaataagta agtaattgta
    37381 taatcaaact gcaatatatt aataatatta gtgaaaatga aaggattata aaatatgtat
    37441 aaatcagaaa atttttcaaa aaaatctgta ttaataaatt catttttaag taaattttta
    37501 aaaataattg gatggggttt ggtaagctta tttacattat cagccttagt actttcaact
    37561 atttccatta taattggatg ggctgtaata cttcctattc aagtatgtgc agtattttta
    37621 cttataggag gagtttgtat ttttaaaggt aagagattag gagaccaaat ttctcgttat
    37681 aaaaaatatt gtacaattat aaacaataga aatattattc cagtagaact tattgcagaa
    37741 aacacatcta aatcattaaa ttttataata aaagatgtac aaaaaatgat agacaaaaac
    37801 tactttataa atacttatat tgataaaaga aataatcaga ttgtgttaac aaatgaagat
    37861 tttattccac caagatatga agatgtagca tatgaagtca aagaagaaga aaagactgat
    37921 gaatccaatg aagttgatac aattataaat aaaggaatga attatctaac acaaataaaa
    37981 gaagctaata aaaatattaa atcagaatca atgggcgata aaattgtaca agtagaagat
    38041 gttacaagta aaatatttga tgttgtaaaa catgacccat caaaacttac tcaaatacaa
    38101 aaatttatgg attattatct tccaaccact ttaaaactat taaattcata tcatacattg
    38161 gaagaacaag gaattgatag agaaaatata acaacaacta tggaaagtat tgaaaataca
    38221 atgaatacga ttgtagtagc ttttgaaaat caattggact atctgtttga agatgaagcc
    38281 attgatattt ctacagatat tactgtttta gagaatatgt tagtccaaga aggattaacg
    38341 agtggtaaat tttaacttca atagaaaaaa tattctgtta tttttaaaca attaattagt
    38401 cataaagtat aaaatgtgta ttatataagt taatcagtac tttatgaagg aagaggagag
    38461 aaagatacaa tgaataattt agatgatata ccagttatgc caactttgac acttgaccca
    38521 tttggagaag aatcaaacac taatgatata gataattctg acttattaat gaaaaaggat
    38581 gaaaaagacc cagaagaaga aaaactgtct gaatctgaac gcaagatggt aaaggaattt
    38641 gcggaaaaaa tagatattac aaatacaaat atgattttgc aatatggagc tggtgctcaa
    38701 aaaaaggtag caagtttttc tgaaacagct ttaaagagtg taaaaacaag agatttagga
    38761 gaagttggag atatgcttac aaatctagtt actgatttaa aagcattttc agcagatgaa
    38821 aaagaacaaa gtggtttttt aggaattttt aaaaaggcaa ataataaaat ttcaaattta
    38881 aaaactaagt atgatagtgc agaggtaaat gtggataaag taagtaaaga gcttcaaaag
    38941 catcaggtta aaatattgaa agatatagca atgcttgata agatgtatga attgaactta
    39001 gcttactcaa aagagcttac tatgtatatt atagcaggaa aacaaaaatt aaaggatatg
    39061 aaagaatatg aaatgccaaa gttgagagaa aaagctcgtt tatctggttc aacagaagat
    39121 gctcaatctg taaatgatat ggtttcactt tgtgacagat ttgaaaagaa aattcatgac
    39181 ttagaattaa ctagaatggt atcgcttcaa atggctcctc agataagatt ggttcaaaat
    39241 agtaataatc tgatggcaga aaagattcaa tcaactatag taaataccat tccattatgg
    39301 aaaaatcaaa tagtgcttgc tcttggaatt tctcacttaa atcaagctat gaaagcacag
    39361 cgtgaagtta gtaatatgac aaatgagctt ttattgaaga atgcagaaac tttgaagatg
    39421 ggaacaatag aaacagcaaa agaatcagaa agaggaattg tagatataga cacaattaag
    39481 aaaactaatc aatctctaat atctactatt gatgaggtag ttaaaataca acatgatggt
    39541 agaataaaga gacaagaagc agaagttgaa ttatcaaaaa tagaaaatga acttaaaagt
    39601 aagcttcttg aatttacagt taaataaaaa ttatactaat ataaaaagag actgtctcaa
    39661 aatagagata agtctctttt tcattgttta aatgattaaa gtatatttat attataaatt
    39721 tctattatct tttaacataa catcatgagc tccaccttca actatactag tagaagatac
    39781 aagtgtaagt ttagcatttt tttgaagttc aggaatgcta agtgctccac agttacacat
    39841 agtagaacga actttactta aagaaagagt tacattgtct ttcaaagaac cagcataagg
    39901 cacataagag tcaacacctt cttcaaaaga aagtttctta tctccaccaa ggtcatatct
    39961 ttgccagttt ctagcacgag cagaaccttc tccccaatac tctttcatat aactaccatt
    40021 tatattaact ttgttagttg gactctcatc aaaacgagag aagtatctac caagcattat
    40081 aaaatctgca cccatagcta aagctaaagt tatatgatgg tcataaacga taccaccatc
    40141 agagcaaatt ggaatataaa tacctgtttt ttcaaagtat tcgtctctag cttgagcaac
    40201 ttcaattata gaagtagctt gtccacgtcc tatacctttt tgttcacgag ttatacatat
    40261 agaaccacca ccaataccaa ctttaacgaa gtcagcacca gcttcagcta ggtaaaggaa
    40321 tccttcgcgg tcaactacat ttccagctcc taccttaact gtatcaccat atttttcacg
    40381 aatgaaatca agtgttattt tttgccactc agaaaaacct tctgaagaat ctatacataa
    40441 aacatcagca ccagcttcaa ctaaagcagg aacacgttca gcaaagtctc tagtattaat
    40501 accagctcca actacatatc tcttagaaga atctaaaagt tcaagtggat tttctttatg
    40561 agaagagtaa tctttacgga ataccatata cataagatta ccattatcat caagtacagg
    40621 aagagaatta agtttgtggt cccatataat gttgtttgct tcctttaaag taacatcttt
    40681 gttagcataa actatagatg acataggagt cataaattca ctaactttag tatctaaatc
    40741 catacgactt atacgataat cacgacttgc aacaataccc aataatttac cagttgaagt
    40801 tccatcttca gtaacagcta ctgtagaatg tccagttttt tcttttaagt caagtatgtc
    40861 ttttaatgtg ttatcaggtt taatatttga atcacttaca acaaaaccag ctttgtggga
    40921 tttaacacgt gctaccatag cagcttcatt ttcaatagtt tgagaaccgt atataaatga
    40981 aataccacct tctttagcaa gtgcaatagc cattttgtca tcagaaacag attgcataat
    41041 ggcagaagtc aaaggtatat tcatataaat atctgcttcc tcgccctttt taaatttagt
    41101 aacaggtgtt tttaaactta cattagcagg tatacaatca gtagaagaga aacctggtac
    41161 aagaaggtat tcactgaaag tatgtgatgg tgtatcaaaa taaaacgcca ttttttaatc
    41221 actccttata tttttatact ttttataatt gatagtatta attataactt attctttaat
    41281 tttattaaag tattttgtca aatattgaga tttttgaaaa atttaaacta ttttaattaa
    41341 atttgtttaa tatatattgc cttatagggt aaagttgtat attaaataat gtttagtgtt
    41401 taatagtagc taatttaaaa ttaatcttta gtgattcata taattacatt tgtatagttt
    41461 atattgataa tattactaga gagtgcataa acctcaaaaa tacagataaa ttaaatctat
    41521 attagtatat ccaaaagtac atttaataaa tttatttaac tgaattatta ttttcatttc
    41581 tattaaattt aaatatttta taaaaatagt attatttaca aaatcatata ctccaaaata
    41641 ctacataaat aaaattaaac aaaaactaaa atgacaaatg tcattatcta aagtgacata
    41701 gaaacggttt cttaaagttg ttactataaa atataaactc tataataaaa gtataacaaa
    41761 agggaatcat atcgatatag aatataattc aagaggaggt aaaattatga gtagttctaa
    41821 tcaatcgaca ataaagacat ctatacagcg agtagggaaa tttttaagtg gtatggtaat
    41881 gccaaatata ggagctttta tagcatgggg tcttataaca gcattattta taccaacagg
    41941 atggatgcct aatgaaaaat tgagtactat aggtgaccca atgataaaat accttttacc
    42001 actattgata gcttatactg gtggtaaagc aatagcagga caaagaggtg gcgtaatagg
    42061 tgcagcagca gctatgggag taattgttgg tgcagatata ccaatgttta ttggagcaat
    42121 gataatggga ccatttgcag gatgggtaat taagaagttt gataaatttg tagatggaaa
    42181 gataccaaca ggatttgaaa tgttagtaaa taacttttca ataggtataa taggtatgct
    42241 tcttgcaata ctaggatttt atgcaattgg accagcaata gtagcaggga cagctcttat
    42301 agaatctgga gttcaattta tagttagcaa aagtttattg cctctagttt cagtatttat
    42361 agaacctgga aaagtattat tcttaaacaa tgcaataaat catggtatat tagggcctat
    42421 aggtatagct gaggcaaaag aagcaggtaa atctataatg ttcttactag aaagtaaccc
    42481 tggaccaggt ttaggagttc tattagcata ttggatgttt agtagaggaa gtgtaaaaca
    42541 atcagcacca ggagctgtaa taatacattt ctttggtggt atccatgaaa tttacttccc
    42601 atatatttta atgaatccag ttttaatatt ggctacaatg gcaggtggag cagcaggaat
    42661 attgactttt tcaatattag gagctgggct tgtagcagca ccatcaccag gaagtatatt
    42721 tgcacttatg gcactagctc caaagggagg attacttcca gtattagcag gagttgcagt
    42781 ggcaacagtt gtatcattct tagtggcagc accatttgtt aagagagctt cagcaaatca
    42841 aagtgaagaa gacagtactt ctttagaaga agctaaagca aaaatgagtg atatgaaatc
    42901 tgcaagtaag aactctgaga aaaatattga ggaaaaacag cttgaagtaa atgagattaa
    42961 gaagattgta tttgcatgtg atgcaggaat gggttcgagt gcaatgggag cttccagatt
    43021 taaaaataga ataaaaaact tagacttaaa tatagaaatt acaaattcat ctgttgataa
    43081 tcttccagat gatacacaaa tagtagtaac tcacaataca ttagttgaaa gagttgctaa
    43141 gaataattca agtgttgaga tagtttcaat aaacaatttt ttaaatgacc caaatttaga
    43201 tgcattattt aaaagattag aatctaaata aaaataaaaa gtaccactaa ttaggagtgg
    43261 ataatttgaa aaaaaagaag attacatcta ggcaaaaaaa gataatacta atgatagtag
    43321 aaaattcaaa gaaaaacatt ccaataacta tttctgagat tgcagggact ttagagctaa
    43381 gttcaagaac tgtacttaga gatatgtctg gaattgaaaa atggtttgat gaaaatgatt
    43441 ttaactttgt aaaaaaacca ggagtgggat tgattttaga ggaaaatata gaaaatcaaa
    43501 actttataat tgagttgtta gaagaagaaa aaatagaaaa agaatacagc aaggaagaaa
    43561 gaaatttaat tatattatca aagctactag tttctaacga gccagtaaaa tcctattatt
    43621 ttgcaaaaat attaaaggta tctgaagggg tactgaataa tgattttgcc ttagcaagta
    43681 aatggttgga aagatttgat attgagcttg ttagaaaacc agggcttggt gtctacttaa
    43741 aaggtcaaga aaaaaacttt agagaggcat atgtaaatct tatatacgat tcattcaatg
    43801 aaaaagaaat actagatatg gtcagaaata taagtgaaaa tatacaaaca gataaagcaa
    43861 tagaaatttt aagtgaaaat agacttttaa atttaatgga caggtgcata ataagaaaag
    43921 ttgaagctac attaacaaag aagctttcag atttagatgt aaatttagct gatagtgcat
    43981 atatagggct tgtagttcat atttcattag ccttacagag gataaaaaat ggtgaaaata
    44041 taactatgga taaagagttt ctaaaagaat tatctataac agaagagttt aaattagcta
    44101 aagaaatcgt aaaaggtatg gaaacagatt ttaacatgga tataccagta gatgaggttg
    44161 gatatataac tatgcatata agaggtgcaa agcaaaggtc atcttcaaac cataaggctt
    44221 taaacttaga tgatatagaa ataatggaaa ttacaaataa gatgatagat ttggcggaag
    44281 atgaatttaa aataagttta aaaaatgacg agaggttatt taaagaccta gcaaatcact
    44341 tagggccttc tataaataga ttgaatatgg gattagaaat aagaaatcct cttttagatg
    44401 aaataaaaag caagtattca tatgcctatg atggagttga aaagatttct agaattataa
    44461 aagataaact aaatataaat tcaatacctg aatcagaaat aggatatatt gcaatgcact
    44521 ttgcatcagc catagaaaaa aatcttatga tgaatactaa tataaatatt gttgtggcat
    44581 gtcccactgg aataggtact tcaagattct tatcaactaa gattgaaaat aaatttccta
    44641 atttaaatat acttgaaacc atatcagcta taaacataga tgaagagtat ttaaaagaaa
    44701 aagatgttga tttaatagtg tctacagttg agttaaatac aagtttaaat tatatatgtg
    44761 taggtccatt tatgagttta gatgatgaac agataatcaa ggaaaaaata aaatctatag
    44821 ctcaaaataa attaatcaat ttaaatgcga aaaatgatac taaaagtaag aataaagtat
    44881 atgaacagat aacagaaagt atgaatatag gaaaagatat tcttcaattt ttagaggaaa
    44941 ttagatttga aaaatttgaa agtaaagatt taagtgagct tattgaagac tcatcaaaaa
    45001 tatttgcaaa atctagtgaa gatataatct ctataaaaga atcgttaaaa gaaagattaa
    45061 aaatctcaat tccatatata gaagaatcaa aaattctatt gttacattgt atgagtgaaa
    45121 gaatagatat tatgaagtta tcaataataa aactagagaa tagaatcgtg ctagattcaa
    45181 atgaagaaat cgataatgta gtttttatgt tacttcctaa aaattcacca agttatcaaa
    45241 gacaaataat gagtgaaata agtggttcat taatagacaa tataattttt actaataaga
    45301 taaataaatt ctctatagaa gagatgacat tagaggtaaa agatatagtt tttaattttt
    45361 atacaaacag attaaaagca tttatagata aataaaatta atattaaaaa ggaaggttga
    45421 tactatgagt aaagtattga atgagaataa tatattttta gggttagata gtgtttcaaa
    45481 ggaagaagct ataactttag caggaagaaa attagttgaa aatggatatg taaaagaaga
    45541 atatatacca gcaatgttag aaagagaaaa agtaatgact acatatatgg gaatgggagt
    45601 tgctattcca catggtgtaa atgaagcaaa aaaagaaata ttatcttctg gaatagttat
    45661 attacaattc cctaatggta tagattttga tggagaaaaa gcatatttat taataggaat
    45721 agctggtgtt ggagatgaac atttagaaat actatctaat atagcagtag ttttagatga
    45781 tgacttaaca gaaagactaa aaaattcaaa tgacaaacaa gcttttatgg aagcttttgc
    45841 caaataatct taggagggat ttaaaatgaa aaaggcgatt cagtttggag caggaaatat
    45901 tggaagaggt tttattggaa gcttgttagt taagtcgggt tatcatgtag tatttgctga
    45961 tgtaaatgag gagatattaa actcaataaa caaagataaa aagtatacta tacacataag
    46021 agatgtagaa tgtatagatg aagtaattga taatataagt gcggtttcat ctataaaaga
    46081 agaaataata gatgagattg tacaggctga aataataact acagcagttg gacctttagt
    46141 tttgactaaa atagcctcta caattgcaaa aggtataaaa gctagaaaag aaaagggatt
    46201 aacaagtaat ctaaatataa tagcatgtga aaatgcaata tacgcaagtt cttctttaaa
    46261 agaagaggta cttaagtatt taaataagga agaagtagaa tatttagaga tgtatgttgg
    46321 ttttccaaac tgttcagttg atagaatagt tcctcctggt aaaaacgaaa atcctcttga
    46381 tgtaacagtt gaaaattttt atgagtggaa tgttgaaaaa caaggattta aaggggaaat
    46441 accaactata gttggaatga atttagctga taaccttatg gcttatatag aacgtaaatt
    46501 gtttacactg aatacaggtc atgctataac agcttatata ggatatttaa aaggatataa
    46561 gactatagaa gagagtataa aagataaatt tatctgtgat atagtcaaaa gtgcaatggt
    46621 agaaagtgga gaaggattga ttaaaaaata caattttgac tcagaagtgc actataaata
    46681 tattgataaa attttaaata gatttaaaaa tccatatctt aatgatgatg tattaagagt
    46741 cggaagggaa ccattaagaa aactaagtga taaagataga ttgattaaac ctttaatgac
    46801 agcaaaatca tatggattat cagttgacaa tttgattctt ggaataggtg cagcgcttca
    46861 ttataataat agtgaagata ctcaaagtgt agaattacaa gagttgataa agtctattgg
    46921 ggtaaaaaaa gccgttgcta aaatagctaa tataagcaat gacgaagaac ttttaaataa
    46981 tatcgaaaaa agttatatat ttatgaaaaa tttataaatt tacttgaaaa aaagtagttc
    47041 tgataaagta actataatat attattctac acagtttgaa ttatttgttg aataatagag
    47101 aattataata tataattaaa aggaataaat taatatattt acctgtatat gtttgataat
    47161 atggttcaaa tgtttctact aagctaccat taatagcttg actacaggag tgaagaagat
    47221 atagtttata cttattttaa attatatatt aagttaatta ctttgaattt taagctcctg
    47281 tctatgatat agacaggagc ttttttagta ttttaatata aaatacttac aagaatagat
    47341 agcaaaatta gaacaaatat aattttttta ttaatataat tttagaaagg gctaggtgga
    47401 agttcaatga aggctttaca agaaaagata ttgagagaag gcagtgtttc aggaaatgat
    47461 atactaaaag ttgatagttt tttaaaccat caaattgatg tagctttttt aaatgaaata
    47521 ggaagagaat ttaaagagag atttaaagga gaaaaggtgg ataagatatt tacaatagag
    47581 gcttcaggaa tagctatagc atcaattgtt tcacagtatt ttgataatgc acctgtagta
    47641 tttgcaaaaa aatcagaatc taaaaatttg gataaaaatg tatatgaaac taatgtatat
    47701 tcatttacta aggcaagaga gtattcagtt aaagtttcta aaaagtacat aaacaaaggc
    47761 gaaaatatat tgatagtgga tgattttttg gcaaatggaa gagctgctct tggacttaaa
    47821 gatttaattg agcaagcaga agctaactta gttggagtag gaattgtcat tgaaaaagga
    47881 tttcaagctg gaggagcact tttaaaggct aatgatgtaa gattagagtc tttggcagta
    47941 gttgaatcta tagataatgg aactgtaaaa tttaggtaat ttatgatatt atataattgt
    48001 gtttagcaca tattttaact atgtaattat ggaggatttt ttatgaggtt ttttatagac
    48061 acagccaata ttgaagaaat aaaagaagca aatgatttag gtgtaatatg tggtgtaact
    48121 actaatccgt ctctaatagc taaagaaggt agagatttta tagaggtagt taaagaaata
    48181 agtgaaatag tagatgggcc aataagtgca gaagtaataa gtttagaaca taaaggtatg
    48241 atagaggaag cagaaaaatt atctaagata cataaaaata tagttataaa aatacctatg
    48301 acagcagaag gtctaaaagc ggtgaaagta ctatcaagta aaggtataaa gactaatgta
    48361 acgcttatat tttctgctgg acaagctctt ttagctgcta gagctggagc tacatatgta
    48421 agtccttttg ttggtagatt ggatgatata tcacaaaatg gtcttgattt aattgaagaa
    48481 atcgttgata tatttagtgt aaatagtatt gaggctcaaa taatagttgc tagtgttaga
    48541 aatccaatac atgttttaca agctgctaga atgggagcag atatagcaac agttcctctt
    48601 aaagttataa accaaatgat taagcatcct ttgacagaca aaggaataga tagctttatg
    48661 aaggattggg aaggtgcttt tttaaaatta taattataaa ctacgcttta taagtatatt
    48721 aaagaggtta ttatggaaat tctaagtaat aaggctaggc tattttgcct agtcttattt
    48781 tggtgtataa tatattgaaa catattattg aaatagatta attttttaag tgaggaggcg
    48841 aaaaatggat aaaatattaa gagagataca aagagaagat aaaaaaaatc catatactga
    48901 ccaagaactt gctgaaatgt taaatgtagc taggtctgaa gtgatatcag ttaggaaaaa
    48961 aaataatatt ttagattcga gagaaagaag aaaaaaaata ttaataaaag atatatcaaa
    49021 aattgtaagt gaaaatcctc aaatgtctga aagaaaaata actgaaatat taatagaaaa
    49081 tggatataat atatcgagaa gtgcagtttc aaaattatta aaagaggaaa atttaaatca
    49141 gtcaaagatt gggattaagg ataaagaccc agcatcatca ggaaagtatg tgaaggtgag
    49201 taaagttgta gaagaagatg gatttgaaga attgataggt ataaagggaa gtttgaaaga
    49261 aaaggtaaat ctagctaagt cagcaataat gtatcctcct aatggccttc atactataat
    49321 atatggagaa acaggagtag gtaaaagtga attagctaca tgtatgtata aatatgctat
    49381 aaaaaacaac attaaagaag agaacagccc atttatagtg tttaactgtg cagactatgc
    49441 agaaaatcct aatctattga tagctcaact ctttggggta gtaaaaggtg catatacagg
    49501 agcagatgca aatagagaag gtcttgtaga acaagctaat aatggaatat tgtttttaga
    49561 tgaaattcat agattgcctg ctgctgggca agaaatctta ttttcattaa tagatagagg
    49621 agaatttaga aggttaggag aaagtagttc taatagaaag gcaaatgttc tcataataag
    49681 tgctacaaca gaaaatccag attctaattt acttcaaaca tttagaagac gtataccaat
    49741 ggtaataaat ttacctaata tgagtgaaag accaaaatct gaaagatatg aaataataat
    49801 aaagtttttt gaaagagaag caaagcgagt aaacaagaat tttataataa ctaaagaagt
    49861 tatgtgtgca cttatgaatt ataagtgtac tggaaatata ggtcagttaa agagtgatat
    49921 acaagtaact tgtgctagag cttttagtaa atcgatattt tctagcgata aggtaattat
    49981 agatttagat agtttaaggg attatataaa aagtggatat tatgattgta attgtaaaaa
    50041 tgaaaagtat tctgagtttt cagttgagga tatatatata gatattagtg aattggtgag
    50101 tggaaaaaat agaattttat ctgataatga gataagcgag atatataatt atgcagaaaa
    50161 agagcttaag gttttggaaa gtaagtgctt ttcagaagaa gagttaaaaa atgcatttat
    50221 agaaaagtta gataagaagt ttaatgctat taaaaacaat aaaaatttat ctgatagaag
    50281 aagtcgaata gactggggag gacaattaaa agagtctaca ctggagataa tggataaggt
    50341 aattgtattt attaaggagc agtttaagca tgtaaatcaa ggtctgtact tggctctagc
    50401 aattcatatt gagcatgcta taggtaggat aaaagatgga aaaactataa taaatccgag
    50461 tttagataaa ataaaagcat caatgccaat ggaatatgag ttgtcaagat atataatggg
    50521 tatagtagaa gatttgacac aagtaacatt tccagaagat gagcttggat atttggctta
    50581 ttatataaat aaattttgtt ataatgagga aagtataaaa gataaagtta aagtagtaat
    50641 agttacgcat ggtaaagttg gaattgaaat gtctaaagtt gtaaatcata ttttaggtat
    50701 agaatgtaca ctaggtatag aaatagcact tacagattca ccatcagagg ggatagagca
    50761 tgtattagaa gagcttcaaa agatagaagc tagaaaaggt attctagttc taattgatat
    50821 gggttctttg gtaattcttg gtgatgaggt tgaaaaaagg cttggaatta gatgtaaaac
    50881 tgtaaataga gtagatacat tattggcaat ggaagcagga aaacttgcaa ccattgaagg
    50941 aaaaagttta gatggtataa tagctgattt aaagaaaaat aagaattatg ctatgataaa
    51001 tacaaataaa tttagttaca gaaaaaacga gtatggaaag aaaaatgtaa tcattacttt
    51061 atgtttgagt ggtgtaggta cagctttaaa tttaaaagag catatagaaa aacaaattaa
    51121 ggaatatggc actttaattg aagtaaagcc agttgctttt ttaaataata atttagaaga
    51181 agagttaaat gatattgaag ctgaatataa tattattgct atctgtggaa ctattgatat
    51241 agattataaa aacgtgcctt ttatttctta taatgaggta cttggtaaaa atggtattaa
    51301 taaagtatta gagcatctaa atagtaaaca accagcttta aatattgaaa accagttgaa
    51361 taatttaata catgaagatt tgattttata caattttgaa ggaatttcaa aggagtatat
    51421 aattgatact cttgtttcaa aacttgaaga aggtggatat gttgattcaa agtatatatt
    51481 aagtgtatat aaaagagaag caatgggaag tgttgtaatg gcctctaagg tagccgtgcc
    51541 acatggactt ccagaaaacg ttataaagcc tgcaatagca atcgcaaggt tgaataaacc
    51601 tatagtatgg gacaataaat ttatggtgga tttggtggta ctactggcac ttaaagaaaa
    51661 taataagaaa gaaatacgaa gcttattttc aaagattaat gaccagcata ctttagaagt
    51721 tttattaaat actgaagata aaaatgaaat aaaagaactt ttaagctaat tattagtacc
    51781 gagaagaaag acaaaaaaat ttgctttagt ataaaattta aaattactca attgctaagt
    51841 agttaattac tctatataag gctagttcta tgaaatttat ttatatgatt ttatagaatt
    51901 agcttttttc ttggtaaata aaatatatga atttatttat gtaaaaagta aattttattg
    51961 gacaattcta tgaaaatttt tcc
//
LOCUS       DACTZW010000023        51909 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.023, whole genome shotgun sequence.
ACCESSION   DACTZW010000023 DACTZW010000000
VERSION     DACTZW010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 51909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51909
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.023"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            462..4010
                     /locus_tag="JAM15_06915"
     CDS             462..4010
                     /locus_tag="JAM15_06915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HAT6797990.1"
                     /translation="MMNRLKPRILGISILFIIIIILTCGAVFKFKFKLDNKLKETTHT
                     YLSEFTEHNIINLKTRLSGQFDMLESIANFIGNLNNINDEMVIDLMDSDVKRSSLIRM
                     TISTLDGECYSNDGITHNVQDRDYFKKAKNGEKNISEPLKSIVNNKEIIVLSTPVYKS
                     GKIVGVLSGIYDSKKLNELLGLSAFDEKADVFVAKKNGDIVAQKTNKNRKTISCIFQL
                     FDKDNCDEDDCLKTIKENMKNDKSGYFNYNLDNEKFMLNYQPLGVNDWYVFSVVPNKI
                     VSIQSENISYDVYIFALEILLVILIFIIYIACIINNNTKIIINEKEKFKVLTDNILGG
                     VKTCLKDEYMTMTYVSQGFLELTGYSCEDLNKIFKNRFKDMIYKDDLDKFNCIILNQL
                     EKQDKIEVEYRIVRKDGSIIWILERSKSINDNKGSECIQGVLTDITELKKIQEELDSK
                     RFEIQAINDSIVGGIVITEINDDFDSIYLNEGYLNMIGYTRKQLEDELNNKLIKLIFK
                     DDRTELINSINKQLKLSDTFASEQRVEKRDGTIIWILLKGRKIIYDNGKSVLCCVIVD
                     ITSAKLLEQELKKSEERHEIILKQTQNIIIEWDIEKDKMNISPNWYNKFKYDPITENA
                     TKNIIKSVDIYHDDMDKFISVIKLTSQGSEYEECEIRLRTRDTIYAWFSIKATTLFDN
                     NGKPYKVVGSLTDIDESKREAEKLKERAEKDPLTDLYNKKASQSLIEEYITLDKKRKG
                     ALMIIDIDNFKGINDNLGHLYGDAVLSEIANDLINLFRATDIVGRIGGDEFIVFIKDI
                     SETRDIINKAEELVKTFERSFLGKGRNYKISLSVGIAKFPQDGMDYMTLFRNADMALY
                     SAKGKGKNCYTLYDKKIDKVQYITNTRNAGDSDNVEMSFKEHITNYIFDILYESSDIE
                     VAVNLILSIVGKHFNVSRMYIFENSDDNRVCKNTFEWCNEGVTSEINNLKNICYKDLG
                     NYLLNFNADGLFYCNDIENLGSDVKKVLKPQGIRSILQCKILEGNEFRGFIGFDECSY
                     NRMWTNDEVNTLTFISKTLSMFLLKMRIQSKLEESLTIQKSVMDNMDIWAYVVDRNTY
                     ELLFINKKMLESASNTHVGDLCYKAIWNNQDKPCKKCPMIYLKDGDDTYKSFMRNKKF
                     EVQANITTTTLKWFDGKDACLIFGSEVTSIEAEENT"
     gene            4195..6129
                     /locus_tag="JAM15_06920"
     CDS             4195..6129
                     /locus_tag="JAM15_06920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgiQ family radical SAM protein"
                     /protein_id="HAT6797991.1"
                     /translation="MENKFLPISKQDMIDRGWEELDFVLVTGDAYVDHHSFGTAIISR
                     VLENAGYKVGIIAQPDWRTTDDFMKLGKPRLAFLVNAGNMDSMVNHYSVSKKHREKDM
                     YSPGGKMGYRPDRATIVYCNKIREAYSDVAIVIGGIEASLRRFAHYDYWSDKVRKSML
                     IDSGADLLVYGMSEKQIVEVANALNDGYDPKYIRHIDGTCYISDTLEEIYDKYILIPS
                     YKEICEDKMKYVEAFKIQYDEQDPFRGNIIVQPHGSKYLVQNKPEKPLSREELDEVYG
                     LPYQKTYHPVYEKFGGIPAIEEVKFSIVSSRGCFGSCSFCAITFHQGRAVQSRSEKSI
                     IDEAIGITNLDDFKGYIHDVGGPTANFRRPACKKQITKGACKNRQCLSPSPCKNLDAD
                     HSEYLHLLRAVRKLPKIKKVFVRSGIRYDYVMADKNNKFLRELIEHHVSGQLKVAPEH
                     ISEEVLKYMQKPAGKTYDKFRQKFFAINEELGKKQYLIPYLMSSHPGSTLNSAIELAE
                     YLRDTHYQPEQVQDFYPTPGTLSTTMFYTGIDPLTMKPVYVPKSKRDKAMQRALLQYR
                     APRNYDLVYSALVEAGREDLIGFGHRCLIKPKNEKPYFNRNNSKKNVSKGTNKNKKTN
                     TNNRSNKNQQKSSTKKKKKH"
     gene            6235..7230
                     /locus_tag="JAM15_06925"
     CDS             6235..7230
                     /locus_tag="JAM15_06925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAT6797992.1"
                     /translation="MKKYISIILLVVVTMVVLVGCSPGKDNPKNKELSVVKQVKVAVP
                     DGLPAVAIAKLANENPEIKEGYETVYSIEKTPEAISTRVMKKDADIAIVPSNMAAIAY
                     NKTSSYNIVGTVGMGSLYLVSTENIKDYSDLVGKEVGCTGKGLTPDITIKSLLLQKDI
                     NYSDIKFNYVNSASELVPLLATGKVKTGIVPEPALSALMSRNPDIKIIKSLNDSWKEV
                     SGSKDGYPQSTLIVKSEFLRDNKDFVDSFVGQLSNSIDWANKNPEELGAYSEKIKIST
                     ESKIIGKSLERANLKYIPVKDMIKDYKNYYEKLANFDDKTLGGKVPDEAIYFVEK"
     gene            7202..7987
                     /locus_tag="JAM15_06930"
     CDS             7202..7987
                     /locus_tag="JAM15_06930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAT6797993.1"
                     /translation="MKQYTLLRNKKNKEQFIDKMEVTLSCVILLFLWQIIALKIDNDI
                     FLPTVGQVFNSIKEIMLNSSFYIDILYSMGRCFFSFLLAMIFAIILSIVSYLNRFFRN
                     LLKPINALTRSIPTMILVVLALIWFEKDSTPFIVGFTIVFPILYDNVLGAILNIDKNL
                     LEMANVYKIRFIDKVLKIYLPAIKFQIISILVSTFSLSLKVAIAGEVYSQPTYGIGTM
                     IQTEKINFNTSGIFAWIIIVLLISAILQIAQKFLARRAFLWKR"
     gene            7975..8673
                     /locus_tag="JAM15_06935"
     CDS             7975..8673
                     /locus_tag="JAM15_06935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6797994.1"
                     /translation="MEKIKLSIENINKRYDSRIIFRDFNIDFYVNEVNCILGKSGCGK
                     TTLLNIISGIIKNDTNNLNIKENLNRVENKLEASYIFQDDRLIDWLTVEENIKIVVNK
                     YYNKTQLNKICDEYLELVGISDYKKFYPQMLSGGIRQRVNIARAFIYPSKNIIMDEPF
                     KSIDAKNTQLIMDNFRNILRKEKRTVLFVTHNIEEALFLADRIFILGDSPIRIKKILK
                     NSKELEKNEVLKLI"
     gene            8796..9269
                     /gene="ybaK"
                     /locus_tag="JAM15_06940"
     CDS             8796..9269
                     /gene="ybaK"
                     /locus_tag="JAM15_06940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HAT6797995.1"
                     /translation="MVKTNAMRILDSNKIDYKVMSYEVKSEHVDGVEVAHDIGRDVNE
                     VYKTLVTQGVSKNIYVYVIPVHENLDLKKAAKVAKEKSVEMIHVKDINKLTGYIRGGC
                     SPIGMKKLYKTFVNESAKNLDTIIVSAGKIGYQIELSPFDLQRLIKVEFVDVIKK"
     gene            9466..10305
                     /locus_tag="JAM15_06945"
     CDS             9466..10305
                     /locus_tag="JAM15_06945"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002845393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase"
                     /protein_id="HAT6797996.1"
                     /translation="MRKIKSEQIVEQVKKLCIEASLYLGEDVLSCIKEKAKSEKSEVG
                     KNILNILVENAEIAKEKNIPICQDTGMAVFFVEIGQEVLIEGDTLTDAINEGVRQGYE
                     EGYLRKSVVSPINRVNTKDNTPAVIHYDMVKGDKIKIEFAAKGFGSENMSKMKMLKPS
                     DGLEGIKKFIIDTVSEAGPNPCPPMVIGVGIGGTVDKCAQIAKKALFRELGEFNKDEN
                     IAKLESELLTAINKLGIGPQGLGGTTTALGLNIETFPTHIAGLPVVVNINCHASRHKK
                     VVI"
     gene            10318..10866
                     /locus_tag="JAM15_06950"
     CDS             10318..10866
                     /locus_tag="JAM15_06950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S-containing hydro-lyase"
                     /protein_id="HAT6797997.1"
                     /translation="MIKITTPVSEIDIAKLNCGDTISLSGILYTARDAAHKRLIDCIN
                     KGEELPFDVYGQGIYYVGPTPTKPGEVIGAAGPTTSYRMDDLTIPLLERGLRLMIGKG
                     KRSDEVIEGMQKYGAVYLAAIGGAGAYISNSIKSCEIIAYEDLGAEAIRKIVVEDLKL
                     TVAIDSYGNNIYEQGRAIYECK"
     gene            10932..12113
                     /locus_tag="JAM15_06955"
     CDS             10932..12113
                     /locus_tag="JAM15_06955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HAT6797998.1"
                     /translation="MSKDYAKLALEMHEINKGKVSVESKVEVKTKDDLSTAYTPGVAE
                     PCLKIHENQDDVYRYTSKGNLVAVVSDGSAVLGLGNIGAEASIPVMEGKAILFKQFAD
                     VDAFPICLKTNDVDEIVKSVELMEPVFGGINLEDISSPRCFEIEERLKKSLSIPVFHD
                     DQHGTAIIVAAAIINSIKLIENKKIEDLEIVINGAGAAGIAIAKILLNMNVKNIILCD
                     RSGALEASIENLNYVQKEMLKVTNIRNEKGPLKDIIKGKDVFIGVSGPGAVTKEMVES
                     MSEKPIILAMANPTPEIMPEEAKLGGAFIMGTGRSDFPNQVNNVLAFPGIFRGALDVK
                     AKEINEEMKIAAAYAIANTISDEEICPEYILPDVFNKNVVKNVAKAVKEAAIKTKVNR
                     I"
     gene            12286..12549
                     /locus_tag="JAM15_06960"
     CDS             12286..12549
                     /locus_tag="JAM15_06960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAT6797999.1"
                     /translation="MEETKFCQCCAMPMGQTDELYGTNKDGSKSTDYCSYCFKDGEFT
                     ADISMEEMIEVCIPHMLQSNKDMTEDEARTMMNNFFPTLKRWK"
     gene            13075..13758
                     /locus_tag="JAM15_06965"
     CDS             13075..13758
                     /locus_tag="JAM15_06965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6798000.1"
                     /translation="MSSILLVEDDLSLIYGLEFSIQKSGFSIDIARTVKEAMQMYEEK
                     NYDLLLLDVSLPDGNGFQICEKVREVSNIPIIFLTASDEEVNVVMGLDMGGDDYITKP
                     FKLNELISRIKALLRRYNVASNVNELSSNNITIKLLENRVFKGEFEVELTTAEYKLLC
                     LFMKNKNIVLTRKNILDKLWDGNGSFIDDNTLSVYVRRLRNKIEDNPENPKFLLTVRR
                     MGYKWNVIK"
     gene            13769..15010
                     /locus_tag="JAM15_06970"
     CDS             13769..15010
                     /locus_tag="JAM15_06970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAT6798001.1"
                     /translation="MKIFSNKDIKIFFLMVISILVMFIIVGQIVVISITNNYKKTLIE
                     HDYNIAGYLYSIGVDKSKIPSAFVTHEDKYILKGKEILDTAGYGFDIDVSFTPSVKLF
                     QSKYIKTMSIYLLVFFTMIIFILYMYFFRQQSKIEEASYKIDLFMNGNINERLNTYEE
                     GSLSKLFSSIDVMSTSLNTHILKEKQSREFLKNTISDISHQLKTPLTALIMYNQILQE
                     ESHNSDVVEAFVQKSQSELERIETLIKNLLKITKIDSKTIILNKNNVNLKNLIVKILY
                     SFETRAEKEGKVISVNGSENTLLFCDYEWMSEALSNLIKNALDNTKENDKITIEWFET
                     TITTIVSVKDTGNGIHVEDIHHIFKRFYRSKFSKDNQGLGLGLPLVKSIVEQHNGTIS
                     VESKLSQGSTFTISFLKLTNM"
     gene            15082..15765
                     /locus_tag="JAM15_06975"
     CDS             15082..15765
                     /locus_tag="JAM15_06975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6798002.1"
                     /translation="MDILVVNNLCKTYGNGYTKVEALKDVSFTVSKGEFVTVVGESGS
                     GKSTLLNLLGGLDTPTSGRIFIDGKEICSMKEEKQTIFRRRNIGFIFQAYNLIPELTV
                     EQNIIFPLLLDYKKPDTIYLDEVLTILGLKDRKNHLPNQLSGGQQQRVAIGRALITKP
                     SIILADEPTGNLDSKNSNDVISLLKVTAEKYNQTIIMITHNTNIASTADRILQVSDGV
                     LTDLGVNRE"
     gene            15762..18092
                     /locus_tag="JAM15_06980"
     CDS             15762..18092
                     /locus_tag="JAM15_06980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAT6798003.1"
                     /translation="MRSYLELVPQYAKVHKKKNRTTILCIIIAVCLVTAIFGLADMAI
                     QCQKIQFIKDDGNWHIVIRNIDEKFISEINSRVDIAHHGRGQVVDNGEFKSKEILIQG
                     LDEEVAKQFNLEIIRGRYPIGENETLIDEDAVKSFNLKIGDFIKIKLADGRNKNYKIV
                     GEYSSISSLRATDKHGLILSILGTQAIKKSETYDYYYITFKEKVNIRKATSDIKNTFN
                     LSDKQIGKNERLLSIIGQGDSDFSKPLYLTAGLLFVLVLVASIIMMYNSFNMSVIERV
                     KFFGLLRCLGSSKHQVKKFVVLESLILSIKAIPIGLVLGSLVTIISSIFLKYVNELFS
                     SMPILKVSFIGIAFGIIVGFLTVILSAIIPAKKASRVSPLSAVRGNLMSKEILNNGKT
                     SKVANTGSFKIETSMGLNHAFSRKKSFVLMTSSFAISIILFLGFSVLIDLMYQGLKPM
                     KPEAPHISIVDPNFKSVLTKEDINEISNIKGVKKVYSRMMTDIEATYNGKKTKSQLIS
                     YEKYQFNWAKKYLLKGEVNENKLQSENLALVEEGHGFDIGDKIYIKNRNAEKELEVGG
                     ILSSIPFEAKDKYIGNIITSENTFTNITGIKGYIIMDIQVDKDTPGDLIENIRRVVDD
                     NLEVRDKRQSNLEVKNSFYTMATFVYGFVFIIAIISMFNIINSMNISVTSRKNYYGVM
                     RAVGISNRQLRRMVIVEAGSYAVSGCLLGSILGLMLHRYMFISLVSSMFHLEWQVPFN
                     LLLITVLTMIIITLLSVRKPVKKICELDIIDSINAQ"
     gene            complement(18273..19115)
                     /locus_tag="JAM15_06985"
     CDS             complement(18273..19115)
                     /locus_tag="JAM15_06985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAT6798004.1"
                     /translation="MINIGDFNKLTVKRKTEFGYFLDGQTNNTKDDILLHNRLIGKNE
                     INIGDEVNAFIFKDSDDRTAATLIPPLAKVGDVAHLKVVDNTDIGTFIDMGLPKDILV
                     PFKAKTYPLFRDEKYLFYIYLDKSKRIAATTDIDSYLLTDHTYNVGDIVTGVVYGFQT
                     NNSAMICVDNKYAGIILHNEYFTELKAGDVLENLHVIKIYEDGKLGLSPRGNRKDELD
                     TLENKILSYLEGSDGYMRFNDKSDPKDISILFNSSKKNFKRALGVLMKKGLIYQDEEG
                     TYLK"
     gene            19410..20144
                     /locus_tag="JAM15_06990"
     CDS             19410..20144
                     /locus_tag="JAM15_06990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAT6798005.1"
                     /translation="MKIVNKSSNIPLHTQLSSIIREMIETGELKEGDAIMPERELCNI
                     QNVSRMTVNKTIVGLVTEGLLYRVQGKGTFVAKQKKKYQFSNVKGFTDVMKEKGVNIK
                     TDILSFEMELPDDLVKRKLGISDNTTNIYKIVRLRYTDGEPFGLEIVYLSEEMCKGLT
                     KGILDNSSLYRVLNEKYGYKIQKAEQVMEPVILSDEESKLLETDEGALALKLHRNSYN
                     REGSPIEYTISIFRTDKYQYEIVLSE"
     gene            20154..21287
                     /gene="nagA"
                     /locus_tag="JAM15_06995"
     CDS             20154..21287
                     /gene="nagA"
                     /locus_tag="JAM15_06995"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HAT6798006.1"
                     /translation="MKCLINGKIILKNQILENKVLVFDEKIIDIADSVPKDCEVIDAD
                     GKYISPGLIDIHIHGNMGKDTMDSTDESIETISKSIMRHGVTSFLPTTMTMDKEHVYD
                     ALEVIKKAQNRKLEGAQVLGAHLEGPFINENYKGAQNEKFIINSKYEFIKEYKDVIKV
                     ITYAPEKDIDFDFTREIKRCTDIVLSIGHSNANYDQAKEAINLGVTNVTHMFNAMTGL
                     NHRDPGVVGAALTTNVYSELIADTIHINKDLFQFILNNKGKERLILITDSIEAGGLED
                     GNYSLGGQKVIVKGNEARLENGALAGSVLSLNKMVFNFLDNTNLKVNEAINLASLNPA
                     TSLGINDKKGSLEIGKDADIAVFDENLDCKMTLCLGDVVYKNI"
     gene            21386..22135
                     /gene="nagB"
                     /locus_tag="JAM15_07000"
     CDS             21386..22135
                     /gene="nagB"
                     /locus_tag="JAM15_07000"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HAT6798007.1"
                     /translation="MRVLVCKDYDGMSKKAAEMIAAQIVLKPNSILGLATGSTPVGMY
                     RDLVKKYNDNIVDFSDVMSFNLDEYYKLPISNDQSYDYFMKENLFNHVNIKLENTHLP
                     NGMADDIEKECLNYEASIDAAGGIDVQILGIGRNAHIGFNEPDTKFAKRTHVVELTES
                     TIEANARFFKSREDVPKKAVSMGIGSILKSKKILLLASGEEKADAVYNTVYGDITPEV
                     PGSILQLHKDTIVIVDEAAASKLNPKDYKLV"
     gene            22310..22582
                     /locus_tag="JAM15_07005"
     CDS             22310..22582
                     /locus_tag="JAM15_07005"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798008.1"
                     /translation="MLKIIMFSGILSSIIKLPIIGILPIGNIKKNTGISDSKKDGKQR
                     RSNLGISIYQLPSFLYSLINNSVPSNKPIPPEEIKLIKMYLLKSCI"
     gene            23242..23946
                     /locus_tag="JAM15_07010"
     CDS             23242..23946
                     /locus_tag="JAM15_07010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6798009.1"
                     /translation="MSKLIYIADDEDNIRNLVKTFLKNEGHDVMDFKTGDELLEQFNI
                     KECDLVILDIMMPGSSGFEVCTKLREKSTVPIIMLTARDTDIDYITGITLGSDDYFTK
                     PFSPMSLVMRVKSIFRRIEFEKKQNYDKYSNSIDMELKFGDVIINKKNKIVTSKNVNI
                     DLTPNEYNLLTYLFENIDRAVSRDELLNKIWGYDIEVETRAADDTVKRLRKKILDTNI
                     LIETVWGFGFRLKEKS"
     gene            23948..25435
                     /locus_tag="JAM15_07015"
     CDS             23948..25435
                     /locus_tag="JAM15_07015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAT6798010.1"
                     /translation="MNNGNDKNRIGKIKSKFKLKFSKKNISIKTRILLSILCLIIIVF
                     MIILVSFNVFLDTYIKTTANEELTKSTEIVEHMDSNFRPIKPPQDDGKLPPKVLSNFM
                     RNVQDKVRMAETQSDADAMVVDSKYNLIFPTREDDFLKNVDEMELIRECIQNEKLDLN
                     SDENTRISTRNKDYYISTVKITSIYGEQDKYLILFIDISKTLNLAQKINIVLISVMCF
                     AGILAIFTAVILSEKIAKPIKELCEFAKKMGQGDFKRTYFDFSDKELVELSTVMNKSA
                     EYLDKYDNEQKIFFQNASHELRTPLMSIKGYAEAIKYNVIDSKHASDIILEESDRLSD
                     MVEDLLYISKIDNITKDFELVECDLREVLSNCGARQNVRAINKGIKFIYEFDEEMVLF
                     ECDEKNISKVFMNLIENALRYAKSEIKIVCKYNQKNIVVIIEDDGIGIKKEDLPHVFE
                     RFYKGVGGNHGIGLSIVKSIVNKHGGRIYVENGKKGAKFTILFKL"
     gene            25709..27253
                     /locus_tag="JAM15_07020"
     CDS             25709..27253
                     /locus_tag="JAM15_07020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HAT6798011.1"
                     /translation="MFLSDFLGQKEGYIKVVRYAKLGFIICLGFCNLITLNPKITMPL
                     IFILIFSTSFLYKGNLKTRLFTTVLLSIFFILSEIVVTSIFVLFVKEGFEIMFENNSI
                     RVLATILSKIVFLLTCKIICLFKKDVHLDMPIKYWLPLFLIPIFSLFLSVSIFDVSKF
                     FSLESLKFLSLISSVGILYINFIVFYLFKFIIDKTKLSMKYEILEKEIIHKEELRLSN
                     ECYKIIVEQTDSVVFEWNIKENKSFVSQAWTEKFGYNNACKNIFKEIKDKDLVHSEDK
                     AIFEGFLESIKKKNIHSQAVYRLKKSNGEYIWCRTSITSIYNDENELLRVVGVIVDVD
                     SDIKKYEELRTRAESDSLTNIYNKGTFEKLVEETIVMNTGDKKDALFIIDLDDFKEIN
                     DNFGHPFGDFVLKTFADKIQASFGNKDLVGRIGGDEFVVYMQDYVTEVNLHKKAKELN
                     RVLSDNYTDLSFSFDSSVSIGIARYPQDGTSFFELFKNADRALYSIKASGKNSYCLFE
                     EELYVQ"
     gene            complement(27945..28775)
                     /locus_tag="JAM15_07025"
     CDS             complement(27945..28775)
                     /locus_tag="JAM15_07025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAT6798012.1"
                     /translation="MSQVSKKYFTTGEFAKICGINKKTLFHYDDIGLFSPELKKENGY
                     RYYSYHQLSIFGIISSLREVKMPLKEIKAYIDKRTPNLLIELLEKKTIDIKNEIEKLN
                     NIQALMESTISFTKNACNIDANTITLKEHEEEYLVKTPVTYKEQFLGDEEENFLYECI
                     NFMDNYELSDYGTIGSIIKGEDIINKDFESYSYLFTKVNKEYKKYPVSIKPKGLYVTA
                     YHKGSYETIYKAYEKLLNFFNQNNLRIGDFVYEEYLLYDISVRDSNEYLTQISAEVKI
                     "
     gene            28848..30575
                     /locus_tag="JAM15_07030"
     CDS             28848..30575
                     /locus_tag="JAM15_07030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6798013.1"
                     /translation="MKKLIHFLKPYRVLIVVVLIFTFLQTLGTLYIPTLTANIVNNGV
                     VKGDIDYIVKTGLIMMIVAGITALSAVLVCKVSANLSSGFCRDIREAVFVKSQDLSIN
                     DFNNIGTASMITRSTSDITLIGQSVFMFIQLVLPAPIITVSGLFLAYSIDKAMTIIIV
                     VVMFLFMLSAFLVGKKLIKLFKMMQIKMDNMNRVLREVVTGVRVIRAFNREHFEKKRF
                     DRTAIDYSETAISINKVFAVLMPIVMLIMNLGIVSIIWFGGMRVSNGNMEIGHIMALI
                     EYCILILFYLIMGVMVFMYIPRAGACADRVNQILDIEPEIVDGNGRKDTVSERGHLVF
                     KNVTFSYAQSEEPVLNNITFEAKSGEVTAIIGSTGSGKSTIANIIPRFFEIQSGEISI
                     NGQDVKKIPQKELRDKIGFVPQKAFLFSGTIEENIRYGKEDASIEEVKHAASIAQADE
                     FISDMEDKYDSFVAQGGNNLSGGQKQRISIARALVRKPEVYVFDDSFSALDFKTDKRL
                     RKALKNEIKDSSAIIIAQRISTIMDANQIIVLNDGKIVGIGKHKDLLENCEVYKQIAD
                     SQLSKEELA"
     gene            30612..32474
                     /locus_tag="JAM15_07035"
     CDS             30612..32474
                     /locus_tag="JAM15_07035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6798014.1"
                     /translation="MSEKRIDEQDIEVLSFEDGISAEKVKDAKKTTKRLLKYMAKQKF
                     KILIIFISVLISSALTVLAPMVMGKAIDQLFNGIKTAVQTGTKFSVNFSTMGGIVSIL
                     LGLYLISAVFIYIQQYIMSGVAQNLVLSMRKDLSDKLNKLPLKYYDSHKKGETLSIVT
                     NDLEKVADSLQEGLMQLITAVVTVVGSIVMMISISVPLTIVSAITLLVSLGITVVIAR
                     KSQERFSENQKALGELNSNIEEIFTGQIVVKAFSKEKDTIRNFKILNQNLYNASRRAQ
                     FSSYAISPIIRFINLIGYVIIAVVGGIFASTGAMTLGSIQAFIQYVNQASEPTTEISY
                     IVNMLQAAIASAERVFTVMDEVEEIKDEESSKVISMPKGKVQFEHVKFGYSDDFILMK
                     DININLNAGDKIAIVGPTGAGKTTLVNLLMRFYEIQGGRITIDGVNIKDLKRGELRTM
                     FGMVLQDTWLFNGSIKENIAYSKSDATMDEIVRAAKSARVDHFIRTLPQGYDTILTED
                     ASNLSQGQKQLLTIARAILSDPSVLILDEATSSVDTRTEVEIQKAMNNLMKGRTSFVI
                     AHRLSTIRDADLILVMKEGTIIEQGSHKELIEKKGFYEELYNSQFTSEYDEDVV"
     gene            32807..33496
                     /locus_tag="JAM15_07040"
     CDS             32807..33496
                     /locus_tag="JAM15_07040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HAT6798015.1"
                     /translation="MNKKLNYRFEMKHKITEADVLALKSRLYPIMKKDENASKDGKYL
                     IRSLYFDTPEDKALLDKLNGVAIREKFRIRFYNNNCSYIRLEKKIKHYNMTSKLSTNL
                     TKKEVINILNNDIEFLKESTNCLLREFYLKLKCERLEAKSIVDYNREAFIYPVGNVRV
                     TIDSDIKTSVNSIDLFNKDLPTVSVIDENMTVLEVKYDEFIPDFIKDLIQINKTTSTA
                     VSKYASSRLYI"
     gene            33601..34287
                     /locus_tag="JAM15_07045"
     CDS             33601..34287
                     /locus_tag="JAM15_07045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HAT6798016.1"
                     /translation="MILIMTFNDIFKSSFIENVSGFSFVDSALALGSAFLVGLFIYMV
                     YKKTYMGIMYSRPFNVSLVALTMLTTFVILAVTSNVVLSLGMVGALSIVRFRTAIKDP
                     MDLVFLFWSLGSGIVLGAGLIPLAVMGSIIMGLILIFFSNKTISETPYILMVNCNNED
                     SEDIATDKIKKVFTKYQIKSKSVTPEKGIELVFEVRMKYGETSLINDLSQVDGVTNAV
                     LVSYNGDYVA"
     gene            34304..36211
                     /locus_tag="JAM15_07050"
     CDS             34304..36211
                     /locus_tag="JAM15_07050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein"
                     /protein_id="HAT6798017.1"
                     /translation="MKDKKFTLLISIMIIFLCAVVGVYSTSSNKSVDLYSDVYIEKYF
                     NRDKVMEVNIEIDESDLKDMNENAIKEEFKVAKVTVDGDTYGNVGIRTKGNSSLTSVA
                     NSDSDRYSYKINFDKYNTSQSMEGLTQLNLNNCYSDPSYMREFLTYSICEEMGLATPE
                     FAYAKVSINGEYHGLYLAVEGLKESYLENNFGNVTGDLYKSDEGSSLQYKGDDPESYS
                     NLIVESDKKTADWSKITKLLKSLDTGEDIEKYLDVDSVLKNIAINTALLNLDSYQGSF
                     AHNYYLYEQDGVFSMLPWDFNMSFGGFSGFGGGSQSIAIDEPTTGNLEDRPLISSLLK
                     NETYKTKYHKYLEEIVTKYLDSDYLENMTTKLHDMIASYVKEDPTAFYTYEEFEKNIT
                     SSIEDSSDNKGFGNKGFDNNNSNNSDSNNNSNSENKRSGNQSDEKEVNAELTSIVVKT
                     NTDNETENKTTNDSESKNNTDKDKSGNDNNQKLEGPMGKGGKSIPGVLEVAEDMSKTI
                     KSQLSGETSSTKQNSGDESSSGIKGSEKFDEDMSGMPEPPEGMDGKMPPGMGNMDKGD
                     MNGKNGNMNMDRNQDNPREAGGFGNRGGGSVSKTTTYFKLILGGASMIIMSIMLVGVS
                     RVKRRRFIKSK"
     gene            36664..37353
                     /locus_tag="JAM15_07055"
     CDS             36664..37353
                     /locus_tag="JAM15_07055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798018.1"
                     /translation="MLQKVLWKFLKLVVGLFICSVGIVLTINCNLGLSPWDVFHQGLS
                     NHIGITIGTASIIVGSIVVIADVVLGENVGWGTVFNMLLIGFFMDLLLYSNLIPEADS
                     LFVGIIMLILGLVLLSVGMVFYMGSGLGSGPRDGLMVAIQKKTGKSLKLIRGTIEVGA
                     LIVGFLLGGKVGIGTIISAFGLGYFTQMVFGLFKLDCSKIKHRFIVDDIKFIKVYMSG
                     EKKATVQNIVK"
     gene            37789..38328
                     /locus_tag="JAM15_07060"
     CDS             37789..38328
                     /locus_tag="JAM15_07060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008677398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HAT6798019.1"
                     /translation="MDIGEKIKRLRTEKQLTQEELANRCELSKGFISQLENNLTSPSI
                     ATLIDILEILGTNLREFFNEIDDERISFTKEDMFETEDEDLKYKLKWLIPNSQKNEME
                     PIIITLYPGGQYKEEKPHEGEEFGYVLAGSIYVHIGEKKNKVKKGESFYFRPKANHYI
                     SNEGKTTAKVIWVSTPPSF"
     gene            38347..39390
                     /locus_tag="JAM15_07065"
     CDS             38347..39390
                     /locus_tag="JAM15_07065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008677397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6798020.1"
                     /translation="MVENIIELRDISKHYEELTVLDNFNLDIKKNEFLTLLGPSGCGK
                     TTTLKIIAGFEYADDGKVLFEGKEINNLPPYERQVNTVFQKYALFPHMDVYENVAFGL
                     KIKKTPKDVIDAKVKEVLKLVALEGFERRQVESLSGGQQQRIAIARALVNEPKVLLLD
                     EPLGALDLKLRQEMQIELKRIQKKLGITFVFVTHDQEEALTMSDTIVVMYKGKIQQMG
                     TPQDIYNEPKNSFVAKFIGESNIFDGIMIEDYKVNFCNRDFECVDKGFEKNENIEVVI
                     RPEDIKMVKPEEGMLKGKVTSTVFKGVHYEIELNENGRLWILHNTKNAEVGTELGMDI
                     YPEDIHIMRKENN"
     gene            39392..40228
                     /locus_tag="JAM15_07070"
     CDS             39392..40228
                     /locus_tag="JAM15_07070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6798021.1"
                     /translation="MKRKSFLAYPYVVWSAIFVIIPLILVVFFSFTKESGGGYAFTLE
                     NYKEVIDPIYMKVFGRSILLAGGATLICLIVGYPVAYIISKARVSRRGSLILLFILPM
                     WMNFLLRTYAWVAILGKNGLLNTFLGWFGIQPLAILYTNFAILLGMVYNFLPFMVLPI
                     YTALSKMDNDLINAAHDLGANNMTVFRKIIFPLSLPGVMSGITMVFMPAVTTFAISRL
                     LGGGKIMLVGDLIEQQFTVVGDWNFGSAISIFMMIVILISMSIMSKFGDESDKEGGGL
                     LF"
     gene            40222..41007
                     /locus_tag="JAM15_07075"
     CDS             40222..41007
                     /locus_tag="JAM15_07075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002846538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6798022.1"
                     /translation="MLKLKKITSNIYLALVFLFLYAPIFALVLFSFNDSKSMARWNGF
                     TWKWYGQLLQNESIMSALYYTIVIAILASVISTIVGTISAIGIHKMRGKSKKLILNVN
                     YLPILNTEIVTAVALMSLFVFVKMEFGFTTMLLAHIMFCLPYVILSVLPKMKQLPDNI
                     EDAAMDLGATPIYALRKVILPQIKPGIVSGFLIAFTMSIDDFIISFFNAGNGVSNLSI
                     EIYGMARRGIKPEINALSTIMFAVVLGLLLLANKKESIVRGIK"
     gene            41007..42059
                     /locus_tag="JAM15_07080"
     CDS             41007..42059
                     /locus_tag="JAM15_07080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein"
                     /protein_id="HAT6798023.1"
                     /translation="MIKLKKTISLIAVGMMTVTLFTGCNKATDSTKVLNVYNVGDYID
                     ESLIDKFEKETGIDVQYSTYDTNEMMYQKVKSGSTHYDLVFPSDYMVEKMKNEGLLEK
                     LDFKNIPNMKYLDKSFLNPVYDKTNEYSVAYMWGTLGILYNKKEVKDPMDSWNILWNP
                     KYKGNIMMFDSVRDTIGITLKKLGYSMNSVNPKEINEAKNLLMKQKDLVLAYVNDEGK
                     DRLLGGEVAMGMLYSGDAVTLMEQNPDLDYAIPKEGTNKWVDAMCVPTTAQNKKEAEL
                     FINFLLDPENAKVNAEYIGYSTPNTGALKLLDPEITQNPVAYPSKEVLDKCETFEDIG
                     ENIKLYDKAWIELKSK"
     gene            42503..43351
                     /locus_tag="JAM15_07085"
     CDS             42503..43351
                     /locus_tag="JAM15_07085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HAT6798024.1"
                     /translation="MNRINKKIDLLILALLVFIFLIVGIVILSIRTENKLNVFIMLAI
                     IFFIIMLTYLSNSVVGLITSSIIIFMYTSYILYNNITHNMDVEFISYMWIIATPVSSI
                     IMGNLNKSINELQNTNKKLSEQYKELVTIDSETGLRNLKIFYNDVNMEISKSIRHNTD
                     FSLMIVKLPYYGNLQTIFGENKTNKIVKYIGSNIIECTRNEDIIYSLQKDMIGILMPN
                     TSLEGSKVVKDRIKKRIKELNLDLNNRGKYVNIDVKIAFLQYKSSFGDSINFKNIVEE
                     ELQYDV"
     gene            43341..45005
                     /locus_tag="JAM15_07090"
     CDS             43341..45005
                     /locus_tag="JAM15_07090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2334 domain-containing protein"
                     /protein_id="HAT6798025.1"
                     /translation="MMFKIFNKSLLKLVVVLSIVLTISNFSLSSYASEITSSTDKVLI
                     IYDSKKETAYNRDILNIMRTLLGRFSSDIELLKLSNYDGEINKNYYSHIFILGINENS
                     YNNDKNTKNLISSLNSYKGTICWLGYGIENLLEHKKYNLDYVGKTNNIVSVNYRGKSY
                     NLDEHYVFNIVESKDTSNKVIGSINDTLNKYPYIINDKNLFYVSKLDLDGVLFYIFCD
                     SLNDIFNIKTFDKGRIFVRIEDVHAFREPKNLVEIADYLSSKNIPFTIALIPAYVNPK
                     NHKVITLSESPEIVKAIKYMQDKGGTVILHGYTHQYKKEEVSGEGYEFWDGKKDEPLK
                     ENMKIFVKDRVLNGLRVCIENGIYPLAFEAPHYAMESEGYKELKKYFSTYMGQHQNND
                     KKFSTNTYPYIIRDTEEFNIFIPENLGYIDPEDKFTFQNIKENLNKLSIVRGFSGGFF
                     FHSYLNIEYLKNTIEYLEKQNIEFMNLRDFNNWVKVDEIQIRNNGDEIIVNYDKDLDE
                     ITKSDTRFKSISNISKILIFIVSISVLIFVIIFIYFKRIDKKKFLK"
     gene            45054..46310
                     /locus_tag="JAM15_07095"
     CDS             45054..46310
                     /locus_tag="JAM15_07095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAT6798026.1"
                     /translation="MRDLNVSEYLFVFSLFSIWSLLLINIILAMGGYIFYFKNFDKEI
                     KEIDEYPMISILVPAHNEAKVIGRTVESLLLLNYPKSKMELIVINDNSSDNSKEILEN
                     IKDRYNNYNFTIINTDSLTGGKGKSNALNIGYTISKGDFIAVYDADNTPDKNALRYLV
                     QTIVMNDELGAVIGKFRTRNKNKNLLTKFINIETLSFQWMSQAGRWQLFNLCTIPGTN
                     FILRRSIIEEIGGWDSKAIAEDTEISFRIYKLGYNIKLVPQSITWEQEPETVKVWIKQ
                     RTRWAKGNIYVLMKYIKNIFKQGRNKIVFDIAYFFSVYFLFLTSVIISDILFVLSISK
                     LVEISIPINFFLIWILSYLLFIIEVSISLTIEKGEATIENIFIVAIMYFTYSQLWLFV
                     AIKGMIEYLKDIIFKREVKWYKTERF"
     gene            46333..48414
                     /locus_tag="JAM15_07100"
     CDS             46333..48414
                     /locus_tag="JAM15_07100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis cyclic di-GMP-binding
                     regulatory protein BcsB"
                     /protein_id="HAT6798027.1"
                     /translation="MKKFIISIISLVLFFSNISLIYKVNADETKIKNYKFERDITIDG
                     VIGSNSTFFEVNKNWDIEEVLLHLNFSKSQILNGDVSSLTVLINNVPIKSIKLNAKTN
                     YKNTLEVLVPKDYIIQGYNEIKIKTYKTISDKICQDDSNTGNWMVIHKESYISIRYKQ
                     KKVENSINEYPYPYAEIENNHKLDTTIVVPDNMTRGETTAVFNLASAFGKITKNDDLK
                     LDVKLYSEMKNWSDDNIIYIGKPENTAEEILDILSIKEQTLLSSNCIIKQVDSPYNKN
                     KKMMVVIGSNEDDLIKASNLLIENRLSNQVLSSSVLVNKETNIKINREQKLNLGHLTL
                     KDLGYSDFLLEGAFNQQALFDVKIPTGKVLDDGSKIILNLRYSDNLDFEKSLVTVSIN
                     DVIVGSKKLDRSHSNNDKLELKIPKDIDNKNYYQVKLTFNLSIKNSNCVTRESNNPWA
                     YVSNNSYLALSTKENETLSFENYPYPFVRDDEFNDLTVIMPDYSGSQAMTWMFRLGVT
                     LGANINSHNGNINVIRGKEFSDKYKDTNIVVFGVPHNNSVIKMLNNNLNIKFDKNYSN
                     FISNDKISFIDDYGKNISTIQLIKSPYNNQKNIMVISSMNEKNLYLGMDYLLNKSKVN
                     DLKGDTLIIDEYGEVEDLAYNLKPKKEVKDSSWNMSINKTTKVFLMISFITIIVAMIL
                     SMLYIKKYKRR"
     gene            48451..49536
                     /locus_tag="JAM15_07105"
     CDS             48451..49536
                     /locus_tag="JAM15_07105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HAT6798028.1"
                     /translation="MRKYMNKFKLKRSILISLIILIFIFIVYFVSIELKDRSLVNNQY
                     KGKIKSANLSVDYEINQVMKDIDKLGLNTVNVPIIINVESINSDIMSIDNNSKEKAIK
                     LIKKLNKKGISTILEAYPWIENGKLYETDWNPINKKRFFYTWQNAILNELIIDVANPL
                     DVNVLNIGSNFVHLEEYQQNWGEIIDFVQSKFDGLVTYRTNWWYTKKDDSSSKLFYEQ
                     KLNNNFFDKLDFISIAAYFELSNKPVNTVDELISALHSSTVNNRGQNIKQEIYNLYKA
                     HRKPIFFGELGFSNRESASSQPWNHTPSKAVNGEEQARCFEAYKKVFENEDWINGFSV
                     FCVGKIDDEKIFYPSKESIKVIKSWYE"
     gene            49590..50714
                     /gene="wecB"
                     /locus_tag="JAM15_07110"
     CDS             49590..50714
                     /gene="wecB"
                     /locus_tag="JAM15_07110"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HAT6798029.1"
                     /translation="MNDIKVMTVFGTRPEAIKVAPLIKELEKRENIKSIVCVTAQHRE
                     MLDQVIETFNINVDYDLDIMEKGQSLNDITCKILNKLPLILNKENPNIILVHGDTTTT
                     LATSLTAFYNKTLVGHIEAGLRTYDKYSPFPEELNRQLTGIIADMHFAPTNLARKNLI
                     SEGKFNNNIFVTGNTAIDALKMTIKENYNHPIIDEIGNDRMILLTSHRRENLGKPMKN
                     IFRAIKRIVDDFEDVQIVYPIHLNPKIRTIADEIFGKFPEKIHIIEPLDVADFHNFLN
                     KSYMIMTDSGGIQEEAPSLGKPVLVLRDKTERTEGIEAKTLKLVGTNEDRIYNSVSDL
                     LINKDNYVQMSKASNPYGDGNASKYIVDIIIKRFNCKYLN"
     gene            50792..51766
                     /locus_tag="JAM15_07115"
     CDS             50792..51766
                     /locus_tag="JAM15_07115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HAT6798030.1"
                     /translation="MARKLIKNLGKSKSVKRVKLLFKKIFITVFIVASIVAIFNITKY
                     FEELYKVRDLKSTKIEYYMDVADEAGDGKVQLSWKALLAIDMVIHDEDLSNIKKKDTL
                     DIGEKFIVEDKNDKGEKVYKVKKFNKVLSELKFDSSQKSRARKYMKDLEYTYLGNKQL
                     DSSEEKIKFIKKLEDSAIREYVDYGILPSITIGQAILESGWGNSKLTKQSNNLFGIKA
                     DKAWKGKSVEISTSEHYNEKIVASFRSYNSLQDSVKDHSLFLINNKRYRKHGLFEAKD
                     YISQAQALENAGYSTAEDKKGNRIYAELLIDVIRSYNLQLIDNKVETK"
BASE COUNT        20686 a         5244 c         8955 g        17024 t
ORIGIN      
        1 aatattttac tagaattatt atctggtaac ttaagttttg agtattaatc taaaatatat
       61 gtttttatag ggtttaaatt ttatgtatac aaaattaatt tgctaactga atcatataaa
      121 aaaaacaaaa tattttttag agggaatgat tagatactat tttctttgtt atgaaattaa
      181 ttgaagagta attaattaga aaaggaataa ataataatga atatattaca ttattacttt
      241 ttgataaatc aaaaataaag ttatagtttt taatattaat taagaatgat gaaatatgaa
      301 taaagatttt acaaataaat cttaagctat cttatttaat tctaatgcag gaagaaggta
      361 aatgtatatt gaaaaaatca tagaaataga agtaaacaac ttaaacaaat acaaaggttt
      421 gcaaaagaag taatataatt atatacaatg aggatgtgag tatgatgaac agactaaagc
      481 caagaatttt aggtattagt atcttgttta ttattataat tattttaaca tgtggagctg
      541 ttttcaagtt taaatttaaa ttagataata aattaaaaga aaccacacat acatatttgt
      601 ctgagtttac agaacacaat ataattaatc tcaagacaag acttagtggt caatttgaca
      661 tgcttgaatc tattgctaac ttcataggaa acttgaataa tataaatgat gaaatggtga
      721 ttgatttaat ggattctgat gtaaagcgaa gttctttaat tagaatgact atctctacat
      781 tagatgggga atgttattct aatgatggaa ttacccataa tgttcaagat agagattatt
      841 ttaaaaaagc taaaaatgga gaaaagaata tttcagagcc tttaaaatct attgttaata
      901 ataaagaaat aatagtttta tctaccccag tttataaaag tgggaaaata gttggtgttt
      961 taagtggaat ttatgattca aaaaagttaa atgagttatt aggattatct gcatttgatg
     1021 aaaaagcaga tgtttttgtt gcaaagaaaa atggagatat agttgctcaa aaaacaaata
     1081 aaaatagaaa gacgatatca tgtatatttc agctttttga caaagataat tgtgatgaag
     1141 atgattgtct aaaaactata aaagaaaata tgaaaaatga taagtctgga tattttaatt
     1201 ataacttaga taatgaaaaa tttatgttaa actatcagcc acttggagtt aatgattggt
     1261 atgttttttc tgttgtgcca aataaaatag tgtctattca gtcagagaat atatcttatg
     1321 atgtatatat ttttgcatta gaaatactac tagttatatt gatttttata atatatatag
     1381 catgtattat aaataataac accaaaatta ttataaatga aaaagaaaaa tttaaagtac
     1441 tcactgataa tatattagga ggggttaaaa cctgtttaaa agatgaatat atgactatga
     1501 catatgtaag tcaggggttt ttagagctta caggttactc ttgtgaagat ttaaataaaa
     1561 tatttaaaaa tagatttaaa gacatgattt ataaagatga tttagacaag tttaattgta
     1621 ttattctaaa tcaattagaa aaacaagata aaattgaagt tgaatataga attgtaagaa
     1681 aagatggaag tataatttgg attttggaga gaagtaagtc tataaatgat aataaaggaa
     1741 gtgagtgtat tcagggagtt ttaactgata taacagaact taagaaaata caagaagagt
     1801 tagattcaaa aagatttgaa atacaggcta tcaatgatag tattgttggt ggaatagtga
     1861 taactgagat aaatgatgat tttgatagta tatatttaaa tgaaggttat ttaaatatga
     1921 ttggatatac acgcaaacaa ctggaagatg agctaaataa taaattaatc aaacttattt
     1981 ttaaagatga tagaacagaa ttaattaata gtataaacaa acaactcaaa ttaagtgata
     2041 catttgcatc tgaacaaaga gttgaaaaaa gggatggtac tattatatgg attttattaa
     2101 aaggaagaaa gataatttat gataatggaa aatctgtact ttgttgtgtt attgtagata
     2161 tcacttctgc taaattatta gagcaagaac ttaaaaagag tgaagaacgt catgaaatca
     2221 ttctaaagca gacgcaaaat atcataatag aatgggatat agaaaaagat aaaatgaata
     2281 tatcacctaa ttggtataat aagtttaaat atgaccctat aactgaaaac gcaacaaaaa
     2341 atataattaa atcagtagat atatatcatg atgatatgga taagtttatt tcagtaatta
     2401 aacttacttc acaaggtagt gagtatgaag agtgtgaaat tagacttaga actagagata
     2461 ctatttacgc ttggtttagt ataaaggcaa caactttatt tgataataat ggtaaacctt
     2521 ataaagtagt aggaagtttg actgatattg atgaatcaaa acgagaagct gaaaagttga
     2581 aagaaagggc agaaaaagac cctcttacag atttgtataa taaaaaagca tcacaatcac
     2641 ttatagaaga gtacataaca ttggataaaa aaagaaaagg tgctttaatg attattgata
     2701 ttgataactt taaaggaata aatgataatt taggacattt atatggggat gctgtattaa
     2761 gtgaaattgc aaatgaccta ataaatctat ttagagcaac cgatatagta ggcagaattg
     2821 gtggagatga gtttattgta tttataaaag atatttctga aacaagagat attataaata
     2881 aagcagaaga attggtaaaa acatttgaaa ggtctttttt aggtaaagga cgaaattata
     2941 aaatatcatt aagtgtagga attgctaagt ttccacaaga tggtatggac tatatgacac
     3001 tatttagaaa tgcggatatg gctctttact cagccaaagg gaagggtaag aattgttata
     3061 cattgtatga taaaaaaatt gataaagtcc aatatataac taatacaaga aatgcaggag
     3121 atagtgataa tgtagagatg tcttttaaag aacatatcac aaattatata tttgatatac
     3181 tatatgaatc aagtgatata gaagtggcag taaatttaat tctaagtatt gtaggtaaac
     3241 actttaatgt gagtcgcatg tatatatttg aaaattcaga tgataatcga gtatgtaaaa
     3301 atacatttga atggtgtaac gaaggtgtaa cctcggaaat taataatctt aaaaatattt
     3361 gttacaagga tttaggcaac tatcttttaa attttaatgc agatgggtta ttttattgta
     3421 atgatattga aaatttaggt agtgatgtga aaaaagtact taagccacaa ggcatacgtt
     3481 caatattaca atgtaaaatt ttagagggca atgaatttag agggttcata ggatttgatg
     3541 aatgttcata taatcgtatg tggactaatg atgaagtgaa cactttgaca tttatatcta
     3601 aaacgctcag tatgttttta ttaaaaatgc gtattcagag taagctagaa gagtctttaa
     3661 caattcaaaa atctgtgatg gataatatgg atatatgggc atatgttgtt gacaggaata
     3721 cctatgaatt attatttatc aataaaaaaa tgcttgagtc agcatcaaac actcatgtag
     3781 gtgatttatg ttataaagcg atatggaata atcaagataa accttgtaaa aaatgcccta
     3841 tgatatattt aaaagatggt gatgatactt ataaatcatt tatgcgcaat aaaaagtttg
     3901 aggtacaggc aaatataact acaactactt tgaaatggtt tgatgggaaa gatgcatgtt
     3961 taatatttgg aagtgaagta actagtattg aagctgaaga aaatacttaa aatactgtgt
     4021 tatatatata cttaaaatcg caatttgaat ttattagact taaaatgtct atataaatca
     4081 tttaagttgt ggttttaagt attttttatg atataattaa gcgttaagaa caaaattaaa
     4141 agatactttt gtataaaaaa atatttgtta aatatatatt gagcaggtga taatatggaa
     4201 aataagtttt taccaataag caaacaagat atgatagata gaggatggga agaattagat
     4261 tttgttctag ttacaggaga tgcttatgtg gaccatcata gttttggaac agcaataata
     4321 tctagagttt tagaaaatgc tgggtataaa gttggaataa tagctcaacc agactggaga
     4381 actacagatg attttatgaa gctaggaaaa ccgagacttg catttctagt taatgcagga
     4441 aatatggatt caatggtcaa tcattattct gtaagtaaaa agcatagaga aaaggatatg
     4501 tattctccag gtgggaaaat gggttataga ccagatagag ctactatagt atattgcaat
     4561 aaaataagag aagcatacag tgatgttgca atagtaatag gtggaattga agcgagttta
     4621 agaagatttg cacactatga ttattggagt gataaggtta gaaagtctat gttaatagat
     4681 agtggagcag atttattagt ttatggtatg agtgaaaagc agattgtaga agtagccaat
     4741 gcacttaatg atggatatga cccaaaatat attagacata ttgatgggac atgctatatt
     4801 tcagatacat tggaagaaat atatgataaa tatatattaa ttccatcata taaagaaatt
     4861 tgtgaagata aaatgaagta tgtagaagct tttaaaattc aatatgatga gcaagaccca
     4921 tttagaggca atataattgt tcaacctcat ggaagtaagt atctggttca aaataagcca
     4981 gaaaaaccac ttagtagaga agaactagat gaagtatatg gattaccata tcagaagaca
     5041 taccatcctg tgtatgaaaa atttggagga ataccagcta tagaagaagt aaaatttagt
     5101 atagtaagtt caagaggctg ttttggtagt tgttcatttt gtgcaataac atttcatcaa
     5161 ggtagagcag tgcaaagtag aagtgaaaaa tcaattattg atgaagcaat aggaataaca
     5221 aatttagatg attttaaagg gtatatacat gatgttggag gtccaacagc taattttaga
     5281 agaccagcat gtaaaaaaca aattactaaa ggtgcttgta aaaatagaca atgcttatct
     5341 ccatcaccat gtaaaaattt agatgcagac cacagtgaat acctacactt acttagagct
     5401 gtaagaaaat tacctaaaat aaaaaaggtg tttgtgcgct ctggaattag atatgattat
     5461 gtaatggcag ataagaataa taaatttctt agagagttga tagagcatca tgtaagtggt
     5521 cagttaaagg tagctccaga acatatatca gaagaagttt taaagtatat gcaaaaacca
     5581 gcaggaaaaa cttatgataa atttagacag aagttttttg ctataaatga agaattaggt
     5641 aaaaagcaat atttgatacc ctatttaatg tctagtcacc ctggttctac cttaaatagc
     5701 gctatagagt tagcagagta tttaagagat actcactacc aaccagagca ggttcaggat
     5761 ttttatccaa ctccagggac tctatctaca accatgtttt atacaggtat tgacccgctt
     5821 acaatgaagc cagtttatgt tcctaaatca aaacgtgaca aggcaatgca aagggcttta
     5881 ttacaatata gagcacctag aaattatgat ttggtatact ctgcgttagt tgaagcagga
     5941 agagaagact taattggttt tggacataga tgtcttataa agccaaaaaa tgaaaagcct
     6001 tattttaata gaaataattc taaaaaaaat gtatctaaag gaacaaataa aaacaaaaaa
     6061 actaatacaa ataacagaag taataaaaat caacaaaaaa gttcaactaa aaaaaagaaa
     6121 aaacattaaa gtataaataa aaatacttaa aaaagaagga ttattcgata aattaacaga
     6181 aattagtata aataaatata attattttaa tgacgttacc tttgggagga agagatgaaa
     6241 aagtatattt ctataatatt attagtggtg gtgactatgg ttgttttggt aggatgttca
     6301 ccaggaaaag ataaccctaa aaataaggag ctatcagttg tcaaacaagt aaaagtagct
     6361 gttccagatg gactaccagc agtggcaata gctaaacttg caaatgaaaa tccagagatt
     6421 aaagaaggat atgaaacagt gtatagcatt gaaaagacac ctgaggcgat ttccactaga
     6481 gtgatgaaaa aagatgcaga tatagctata gttccttcaa acatggctgc aatagcgtat
     6541 aataaaactt catcatataa tattgttgga actgtaggaa tgggttcact ttatttggtg
     6601 tcaacagaaa atataaaaga ttattctgat ttagttggta aagaagttgg atgtactgga
     6661 aaaggactta ctccagacat aactataaaa agtcttttgt tacaaaagga tataaattat
     6721 tcagatataa aatttaatta tgtaaattca gcaagtgaac tggtaccatt attggctact
     6781 ggtaaagtta agacaggtat tgttccagaa cctgcactta gtgctttgat gtctagaaat
     6841 ccagacataa aaattataaa aagtttaaat gactcatgga aggaagtaag tggttcaaaa
     6901 gacggttatc ctcaatctac tttaattgta aagtctgaat ttttaagaga taataaagat
     6961 tttgttgatt cttttgtagg tcaattatca aatagtatag attgggcaaa caaaaatcct
     7021 gaagaattag gtgcatattc tgaaaaaata aaaatatcta ctgaatcaaa gataatagga
     7081 aaatctcttg aaagagctaa tttaaaatat attccagtta aggacatgat taaagattat
     7141 aaaaattact atgagaaatt agctaatttt gatgataaga cattaggagg caaagtacca
     7201 gatgaagcaa tatactttgt tgagaaataa aaaaaataaa gaacaattta tagataaaat
     7261 ggaggtaaca ctttcttgtg ttatcctctt atttttatgg caaattattg ctttaaaaat
     7321 tgataatgat atttttttac caacagtagg tcaagtattt aatagtataa aagagattat
     7381 gctaaattct agtttctata tagatatact ttactctatg gggagatgtt tttttagttt
     7441 tttactggct atgatttttg ccattatact ttcaatagta tcttatttaa atagattttt
     7501 tagaaactta ttaaagccaa tcaatgcttt gacacgttca ataccaacta tgatattggt
     7561 agtacttgca cttatttggt ttgaaaagga tagtacccct tttatagttg gatttactat
     7621 agtttttcct atattgtatg ataacgtttt gggcgctata ttgaatatag acaagaactt
     7681 attagaaatg gctaatgtgt ataaaataag gtttatagat aaggtgttaa aaatttattt
     7741 accagccata aaatttcaaa ttatatctat actagtatca acattctctt taagtttgaa
     7801 agttgctata gcaggagagg tatatagtca acctacatat ggtattggaa ctatgataca
     7861 gactgaaaaa attaacttta atacatctgg aatatttgca tggataatta ttgttctttt
     7921 aatatctgct attttacaaa tagcccaaaa gtttttagca aggagagctt ttttatggaa
     7981 aagataaagt tgagtattga aaatataaat aaaagatatg atagtcgtat tatatttaga
     8041 gattttaata ttgattttta tgtaaatgag gtaaattgta tacttggaaa atctggttgt
     8101 ggaaaaacta cactcttgaa cataataagt gggattatta aaaatgacac caacaatcta
     8161 aatatcaaag aaaatttaaa tagagtagaa aataagcttg aagctagtta catatttcaa
     8221 gatgatagac ttatagactg gttaacagta gaagaaaata taaagatagt tgtaaataaa
     8281 tattataata aaactcaatt aaataaaatt tgtgatgaat acttggaatt ggttggaatt
     8341 agtgattata aaaaattcta tcctcaaatg cttagtggag gtattagaca aagagtaaat
     8401 attgctagag cttttatata tccatcaaaa aacattataa tggatgaacc ttttaaatct
     8461 attgatgcaa agaatacaca gcttataatg gataatttca gaaatatatt aagaaaagaa
     8521 aagagaactg tgttatttgt aactcataat attgaggaag cattgttttt agcagatagg
     8581 atatttattt taggagactc tccaattaga ataaaaaaaa tattaaaaaa ttctaaggaa
     8641 ttggaaaaaa atgaagtttt gaagttgata tagagttata ataatactgt cgttttaaaa
     8701 tatatttggt taaaatctat aagactatat taaaatagta cagaatattc aaaactgtgt
     8761 ataatgttcg tattttataa aaaggaagtg aatgtatggt taagactaat gctatgagaa
     8821 tattagattc aaataagatt gattataaag taatgtctta tgaagtgaaa agtgaacatg
     8881 tggatggtgt tgaggtggca catgatatag gaagagatgt aaatgaagta tataagacat
     8941 tagtaactca aggagttagt aagaatatat atgtatatgt aataccagta catgaaaact
     9001 tagacttaaa aaaggctgca aaagtagcta aagagaaaag tgtagagatg attcatgtaa
     9061 aagatataaa taagcttaca ggttatatta gaggcggatg ttctcctata ggtatgaaaa
     9121 agctttataa aacttttgta aatgaaagtg caaagaattt agatacaatt attgtgagtg
     9181 caggaaaaat aggatatcaa atagaactat ctccatttga tttacaaaga cttataaaag
     9241 tagaatttgt agatgtaata aaaaaataag aattacatat aaaatataga gcttatattc
     9301 ttaataatag gtgttgtaat attaataaaa tgaataataa ttttaaaata aatattcagt
     9361 tacttatgtg taattggtat aaaaatattg agaaatttta aaaacaatgg taaagtgtaa
     9421 gtataatcac gaatattttt tataaagtaa tggagggatg ttcgcttgag aaaaataaaa
     9481 tctgaacaaa tcgtcgagca ggtaaaaaaa ctttgtatag aagcgagcct atatttagga
     9541 gaagatgttt taagttgtat aaaagaaaaa gcgaaaagcg aaaagagtga agttggaaaa
     9601 aatatattga atatattagt tgaaaatgct gaaatagcta aagaaaaaaa tataccaata
     9661 tgtcaagata ctggtatggc tgtatttttt gttgaaatag gacaagaagt tttaattgaa
     9721 ggagacacac ttactgatgc tataaatgag ggagtaagac aagggtatga agaaggctac
     9781 ttaagaaaat ctgttgtaag tccaattaac agagtaaata caaaagataa tacacctgct
     9841 gttattcatt atgatatggt aaaaggtgat aaaattaaaa tagaatttgc agctaaggga
     9901 tttggaagcg aaaatatgag taagatgaaa atgttaaagc catcagatgg attggaagga
     9961 attaaaaaat tcataataga cacagtttca gaagctggac ctaacccatg ccctcctatg
    10021 gtaattggag ttggtatagg tgggactgtg gacaaatgtg ctcaaatagc taaaaaggca
    10081 ctttttagag aactaggtga atttaataag gacgaaaata tagcaaaact tgaaagtgaa
    10141 ctattaacag ctattaataa acttggtata ggacctcaag gcttaggtgg tactacaaca
    10201 gctttgggat taaacataga gacttttcct acacacatag caggtctacc tgttgttgta
    10261 aatataaact gccatgcatc aagacataag aaggtagtaa tttaggagga aaataaaatg
    10321 ataaaaataa ctacacctgt aagtgaaatt gatatagcaa aattaaattg tggagataca
    10381 attagtttga gtggtatact ttatacagca agagatgctg ctcataaaag attgatagat
    10441 tgtataaata aaggtgaaga attaccattt gacgtatatg gtcaaggaat atattatgta
    10501 ggacctactc ctacaaagcc aggagaagtt ataggtgctg caggtccaac gacgagttat
    10561 agaatggatg atttgactat acctctttta gaaagaggtc ttagattgat gataggcaag
    10621 ggaaaaagaa gtgatgaagt tatagaaggt atgcaaaaat acggagcagt ttatcttgct
    10681 gcaataggag gagctggagc gtatatttca aattcaataa aatcatgtga aattattgca
    10741 tatgaagatt taggagctga agctataaga aagattgtag tagaagacct taaacttaca
    10801 gtagcaatag atagctatgg aaataatata tatgagcaag gtcgagcaat ttatgaatgt
    10861 aaataatgtt tagaaataaa tatgaatatc aaaattaaaa atagttgtgt atattttaag
    10921 gaggaaaatt gatgtctaag gattatgcaa aattggcatt agaaatgcat gaaatcaaca
    10981 aagggaaagt aagtgtagaa agcaaggtag aagttaaaac taaggatgat ttatcaacag
    11041 catatacacc aggggttgct gaaccttgtt taaaaataca tgaaaatcaa gatgatgttt
    11101 atagatacac ttctaaaggg aatctagtag cagtagttag tgatggaagt gctgtacttg
    11161 gattaggtaa cattggtgct gaagcatcta tacctgttat ggaaggtaaa gctatattat
    11221 ttaaacaatt tgcagatgta gacgcttttc caatatgttt aaagactaat gatgtagatg
    11281 agatagttaa atctgtagag ttgatggagc ctgtatttgg aggtataaat ttggaagaca
    11341 tatcttctcc aagatgtttt gagatagaag agagattaaa aaaatcttta agtatacctg
    11401 tttttcatga tgaccaacat gggacagcaa taatagttgc agcagccata ataaactcaa
    11461 taaagttaat tgaaaataaa aaaatagaag atttagaaat agttataaac ggagcaggag
    11521 ctgctggtat agccatagca aagatactac ttaatatgaa tgttaaaaat ataatcttat
    11581 gtgatagaag tggagcattg gaagctagta tagaaaatct aaactatgtt caaaaagaaa
    11641 tgttaaaagt aacaaatata agaaatgaaa aaggaccttt aaaagatatt ataaaaggaa
    11701 aagatgtatt tattggtgtt tcaggtccag gagctgttac aaaggaaatg gttgaaagta
    11761 tgtctgagaa gccaataata ttggcaatgg caaatcctac tccagagata atgccagaag
    11821 aagcaaaatt aggtggagca tttataatgg gaacaggtcg ttcagacttc cctaatcaag
    11881 tcaataatgt actggctttt cctggaatat ttagaggagc attagatgtt aaggctaaag
    11941 agataaatga agaaatgaag atagctgctg catatgcaat tgctaataca ataagtgatg
    12001 aagaaatatg cccagagtat atattaccag atgtatttaa taagaatgta gtaaaaaatg
    12061 ttgctaaggc agttaaagaa gcagcgataa aaactaaagt aaatagaata taaattttta
    12121 taacttatta aaaactagaa aagtataaaa gactagtgaa attatgtaca gtgggatgat
    12181 tttattagtc tttttatttt aaatatgaca caataatgtc atattaagct tgatataatt
    12241 ttaatatggt taggagccaa agaaaaatat aaggagtgat ttaaaatgga agaaactaaa
    12301 ttttgccaat gctgtgcaat gccaatggga caaactgatg aattatatgg gacaaataaa
    12361 gatggaagta aaagtactga ttattgtagt tattgtttta aagatggtga gtttacagct
    12421 gatataagta tggaagagat gatagaagtt tgtatccctc atatgcttca aagtaataag
    12481 gatatgactg aagatgaagc aagaacaatg atgaacaatt tctttccaac attaaaacgc
    12541 tggaaataat tttatgcaaa attagttata tgcaaaacat gaaatatggt gttgagaata
    12601 aggggtggtg tgctttatag cataccacct gttttgttac ttgctagttc agttattctt
    12661 gtatgcttaa atatgttctc atctctcttt ctattttaaa ttgtaaaaat ctaaaatatg
    12721 ttatttatat tctacttctt tatccatgtc tttttctacc tcaagtcaaa tacaactaca
    12781 aaatcatcat tttcaattca ctgtttaata gaattaacag ataaagagtt ataaaatttt
    12841 ctatttttta tataaaataa tacaggtcaa gctgacttct agctacttgg gatagtgtat
    12901 atatttatga tagttatagg agtaatacca atcattagac tgttgatttg tgtagtcttt
    12961 tgtaaaaaca tttgttttaa tatattgagt ttttgaaaaa gtaaaattat aattataata
    13021 aattaagtgt aataatgtat tagaagtaaa aataattaaa atagaggtga ttaaatgagc
    13081 agtatattgt tagttgaaga tgatttaagc ttgatatatg gattagagtt ctctatacaa
    13141 aaaagtggat ttagtataga catagcaagg acagtaaaag aagctatgca aatgtatgag
    13201 gaaaaaaatt atgacttatt gcttttagat gtatccctac ctgatggtaa tggatttcag
    13261 atttgcgaaa aagtacgaga ggtttctaat atacccatta tatttttgac tgcttcagat
    13321 gaagaggtaa atgtagtgat gggtcttgat atgggtggcg acgattatat aacaaaacct
    13381 tttaaattaa atgaattaat ttcaagaata aaagcattac ttagacgtta taatgttgca
    13441 agtaatgtga atgaattaag ttcaaataat attactatta aattacttga aaatcgtgtt
    13501 tttaaaggtg aatttgaggt ggaacttacc acagcagaat ataaattatt gtgcttattt
    13561 atgaaaaata aaaatattgt acttactaga aaaaacatat tggacaagtt atgggatgga
    13621 aatggtagct ttatagatga caatacatta tcagtatatg taagacgatt gagaaataaa
    13681 attgaagata atcctgaaaa tcctaagttt ctattgaccg ttagaagaat gggttataag
    13741 tggaatgtaa ttaagtgagg gtattaatat gaagatattt tctaataaag atataaaaat
    13801 atttttttta atggttatat ctattttagt aatgtttatt atagtagggc aaatagtggt
    13861 tataagtata actaacaatt ataaaaaaac gttgatagaa catgattata atatagctgg
    13921 atacttatat agtataggtg ttgataaatc taaaatacca tcagcatttg ttacacatga
    13981 agataaatat attttaaaag gaaaagaaat actagataca gctggatatg gatttgatat
    14041 agatgttagc tttacaccaa gtgtaaaatt gtttcaaagt aaatatataa aaactatgtc
    14101 tatctattta ttagtatttt ttactatgat tatttttata ctatatatgt atttttttag
    14161 gcaacaaagt aagatagaag aggctagtta taaaattgat ttatttatga atggaaatat
    14221 aaatgaaaga ctaaatacat atgaagaagg tagcttatca aaattattta gttcaataga
    14281 tgttatgtcg acatctttaa atacacatat attaaaagaa aaacagagca gagaatttct
    14341 taaaaataca atttcggata tatcgcatca attaaaaact ccacttacag ctttaataat
    14401 gtacaatcag atactacaag aagaaagtca taatagtgat gtcgttgaag cttttgtaca
    14461 aaaaagtcaa agtgaactag aacgcattga aacattgatt aagaatttat taaagattac
    14521 aaagatagat tcaaaaacaa taattctcaa taaaaataat gttaatctta aaaatttaat
    14581 tgtcaaaatt ttgtatagct ttgaaactag ggcagaaaaa gaaggaaagg ttatttctgt
    14641 aaatggttca gaaaatacat tgttgttctg cgattatgaa tggatgtcag aggctttaag
    14701 taatcttata aagaatgcat tagataatac aaaagagaat gataaaataa cgatagagtg
    14761 gtttgagacg actataacca ccattgtttc agttaaagac actggaaatg gaatccatgt
    14821 tgaggatatt catcatatat ttaaaaggtt ttatagaagt aagttttcaa aagataatca
    14881 aggtttagga ctgggattac cactagttaa atctattgtg gaacaacata atggtactat
    14941 ttctgtagaa agtaaactat cacaaggaag tacattcacc ataagttttt taaagcttac
    15001 taatatgtaa gataaaatac atcttgcagt aaggtatata gattattatt atattaatca
    15061 attagaaagg tgagagagaa aatggatatt cttgtggtta ataatttatg taaaacatat
    15121 ggaaatggat atacaaaagt agaggcattg aaagatgtat cctttacagt ttcaaaagga
    15181 gagtttgtga ctgtagttgg agaatctggt tcaggaaaga gtacactatt aaatctctta
    15241 ggaggtcttg atactccaac atcagggaga atatttattg atggtaaaga aatatgttca
    15301 atgaaagagg aaaaacagac tatttttaga cgtcgtaaca tagggtttat atttcaggca
    15361 tataacctta taccagaact aactgtggag caaaatataa tattcccatt gttattagat
    15421 tataaaaaac cagatactat ttacttagat gaagtattga ctattttagg tcttaaagat
    15481 aggaaaaatc atcttccaaa tcaattatct ggtggtcaac aacagagagt tgcaattgga
    15541 agggctttga ttacaaagcc aagtattata ctggcagatg agccaacggg aaatcttgac
    15601 agtaaaaata gtaatgatgt aatttcactt ttaaaagtga ctgcagaaaa gtataatcaa
    15661 accattatta tgataactca taatacgaat atagcttcta cagcagatag aatactacag
    15721 gtttctgatg gtgtgcttac agacctgggg gtgaatagag aatgagaagc tacttagaat
    15781 tagtaccaca atatgcaaaa gtacataaga aaaaaaatag aactacaatt ttatgtatta
    15841 ttattgcagt atgcttagtt actgctatct ttggacttgc agatatggct atacaatgtc
    15901 aaaagataca atttattaaa gatgatggaa attggcacat agtaattaga aatattgatg
    15961 aaaagtttat atcagaaata aatagtagag tagatatagc tcaccatggt agggggcaag
    16021 tcgttgacaa tggagagttt aaatcaaagg agattttgat acaaggttta gatgaagaag
    16081 tagcaaagca atttaactta gaaataataa ggggtcgtta tcctattggg gagaatgaga
    16141 ctttaataga tgaggatgca gttaaaagct ttaatctaaa aataggagat tttatcaaaa
    16201 taaaattagc agatggtaga aataaaaatt ataagatagt aggtgaatat tcatcaatat
    16261 caagcttaag agctacagat aaacatggat taatactttc aatattgggt acacaagcta
    16321 ttaaaaaatc agaaacgtac gattattatt atattacatt taaagaaaag gttaatatta
    16381 gaaaagccac ttctgatatt aaaaatacct tcaatttaag tgataaacaa atcggtaaaa
    16441 atgaaagatt actttctatt ataggtcaag gcgactctga cttttctaaa ccactgtatt
    16501 taacagcagg attacttttt gtacttgttt tagtagcaag tattatcatg atgtataata
    16561 gttttaacat gagtgtaatt gagagagtta aattttttgg tctgttacgt tgtctagggt
    16621 catcaaaaca tcaagttaaa aaatttgttg ttttagaaag tttaatttta agtataaaag
    16681 ctattccaat aggcttagta ttaggaagtc ttgtaactat tatatcttct atatttctta
    16741 agtatgttaa tgagttattc agctcaatgc caattttaaa agttagtttt attggtattg
    16801 catttggaat aattgtaggg tttttaactg taatattatc agctattatt ccagcaaaaa
    16861 aagcttcccg tgtatctcca cttagcgctg tacgtgggaa tctaatgtcc aaagaaattt
    16921 taaataacgg gaagacaagt aaagttgcaa atacaggaag ttttaaaatt gagacttcta
    16981 tgggattaaa tcatgctttt tcaagaaaga aatcttttgt acttatgact tcttcatttg
    17041 ccattagtat tatactattt ttaggtttta gtgtgcttat agaccttatg tatcaaggac
    17101 ttaagcctat gaagccagaa gctcctcata tatctattgt tgaccctaat tttaagtctg
    17161 ttttaactaa ggaagatatt aatgaaataa gtaatatcaa aggagtaaag aaagtataca
    17221 gtagaatgat gacggatata gaagctacat ataatgggaa gaagacaaaa tcacaattaa
    17281 tttcttatga aaagtatcaa tttaattggg caaaaaaata tctattaaaa ggagaagtta
    17341 atgaaaataa actacagtca gaaaaccttg cattagtaga agaggggcat ggatttgata
    17401 taggagataa gatatatatt aaaaatagaa atgctgaaaa agagttagag gtaggaggta
    17461 tactttcctc aattccattt gaggctaaag ataaatatat tggaaatatt ataacatctg
    17521 aaaatacttt tacgaatata acaggtataa agggttatat aataatggat attcaggttg
    17581 ataaagatac tcctggagat ttaattgaaa atataagacg tgtagtagat gataacttag
    17641 aggtcagaga taaaagacaa agtaacttag aggttaaaaa ttcgttttat actatggcaa
    17701 catttgtata tggatttgtg tttattattg cgattataag catgtttaat atcataaata
    17761 gcatgaatat aagtgttaca agtagaaaga attactatgg tgttatgcgt gcagtaggca
    17821 tatccaacag acaattaaga agaatggtaa tagtagaggc aggttcatat gcagtgagtg
    17881 gttgtttatt aggtagtata ctaggattaa tgttacatag gtatatgttt atctcgttag
    17941 taagttcgat gtttcattta gagtggcaag taccttttaa tttactactt atcactgtac
    18001 taactatgat aataataact ttattatcag taagaaaacc agtcaaaaag atttgtgaat
    18061 tagatataat agactcaata aatgcacaat aaatataact gttgatttaa attaaaaaaa
    18121 cgaagtaaaa atgaaataga aaatattttt catttttact tcgtttttta tattataaaa
    18181 tttttgttat gttacaaaat ttctataaag atgatgtgaa tctaaacatt atatgacaac
    18241 gtgagcattt aagttaaaat attttaaata tactatttta gataagttcc ttcttcatct
    18301 tgataaatta atcctttttt cataagcact ccaagagctc gtttaaaatt tttcttactt
    18361 gaattgaata atatagaaat atctttaggg tcagatttat cattaaatct catatatcca
    18421 tcagaaccct ctaaataact taaaatctta ttttctaaag tatcaagttc atcctttcta
    18481 tttcctctag gagaaagacc aagttttcca tcttcatata tttttatgac atgtaaattt
    18541 tcaagaacat caccagcttt tagttcagta aagtactcat tatgaagtat tataccagca
    18601 tatttattgt ctacacatat cattgcagaa ttattagttt gaaatccata tacaactcca
    18661 gttacaatat ctcctacatt gtaagtatgg tctgttaata aatatgaatc tatatctgta
    18721 gtagcagcaa ttcttttgct tttgtctaaa tatatataaa ataaatattt ttcgtctcta
    18781 aatagtggat aagtcttagc tttaaaagga actagtatgt ctttaggaag tcccatatct
    18841 ataaaagtac caatgtccgt attatcaact acttttaaat gtgctacatc cccaacctta
    18901 gctaaaggcg gtattaaagt tgcagcagtt ctgtcatcag aatctttaaa tatgaaagca
    18961 tttacttcat cacctatgtt tatttcattt tttccgatta atctattatg aagaagtata
    19021 tcgtcttttg tgttattagt ttgtccatcc aaaaaatatc caaattcagt ttttcttttt
    19081 actgtaagtt tattaaaatc acctatgttt atcaaattaa aatcatcctc tcattttata
    19141 tttataattt agccataata tacttatgta gtagtttgtc acagtatcta tattagtatt
    19201 agtgaaattt acaataaata atatagttat ttatgtattt ttcaattctc tagcttctta
    19261 tatagtataa actccaattt cttttttgtc tttaggtttt actaaaattt ttacaaaata
    19321 agttaaaaag tattgaaata aaatttcttt taaagtataa ttggtatata ccaaaattgg
    19381 tatataccat atcgaaaagt ggtgactata tgaaaatagt aaataaatct agtaatatac
    19441 cattgcatac tcaattaagt tcaataataa gagagatgat agaaactggt gagcttaaag
    19501 agggtgatgc aataatgcca gaaagagaac tttgcaacat acaaaatgta agtcgtatga
    19561 cagtaaataa aaccattgtt ggattagtca cagaaggact tctttatagg gtacaaggta
    19621 aagggacatt cgttgcaaag caaaaaaaga agtatcagtt ttcaaatgta aaaggtttta
    19681 ctgatgttat gaaagaaaag ggagtaaaca taaaaacgga tatattatcc tttgagatgg
    19741 aactaccaga tgatttagtt aaaagaaagc ttggaataag tgataatact acaaatatat
    19801 ataagattgt cagacttaga tatactgatg gagagccatt tggattagaa atagtatatc
    19861 tatcagaaga aatgtgtaaa ggtctaacaa aagggatatt ggataattct tcattatata
    19921 gggttttaaa tgaaaaatat ggctataaga tacaaaaagc tgaacaagta atggagccag
    19981 taatactttc agatgaagaa agtaagcttc ttgaaacaga tgaaggtgct ttagctctta
    20041 aacttcatag aaattcctat aatagagaag gtagccctat agaatatacc atatcaatat
    20101 ttagaacaga taaatatcaa tatgaaatag tattgagtga gtaggtgaat aatatgaaat
    20161 gtttaattaa tggaaagata atattaaaaa atcaaatctt ggaaaataaa gtattagtat
    20221 ttgatgaaaa aataattgat atagctgata gtgtaccaaa agattgtgaa gttatagatg
    20281 ctgatggaaa atatatatct ccagggctta ttgatattca tatacatgga aatatgggaa
    20341 aagatacaat ggattcgact gatgaatcta ttgaaacaat ttcaaaatca attatgagac
    20401 atggagtaac atcttttctt ccaactacaa tgactatgga taaagaacat gtttatgatg
    20461 cacttgaagt tattaaaaaa gcccaaaata gaaagcttga aggggcacaa gtattaggag
    20521 cacatttaga aggacctttt ataaatgaga attataaggg agcacaaaat gaaaaattta
    20581 taataaattc aaaatacgaa tttataaaag aatataaaga tgttataaaa gttataactt
    20641 atgctccaga aaaagatatt gattttgatt ttactagaga aataaaaaga tgtacagata
    20701 tagttttatc tattggtcat agtaatgcaa attatgacca agctaaagaa gctataaatt
    20761 taggagtaac taatgtaact cacatgttca atgcaatgac tggtttaaac catagagacc
    20821 caggcgttgt tggtgcagca cttacaacta atgtgtacag tgagctaata gcagatacaa
    20881 tccatataaa taaagattta tttcaattta tactaaataa taaagggaaa gaaagactga
    20941 ttttaataac agattctata gaagctggtg gtcttgaaga tggcaattat tctcttggag
    21001 gtcagaaagt catagttaag ggtaatgaag ctagacttga aaatggagca ttagctggaa
    21061 gtgtgttgtc tttaaataaa atggtattta acttcttaga taatacaaac cttaaagtga
    21121 atgaagcaat taatttagct tctttaaatc cagcaacatc tttgggaata aatgacaaaa
    21181 aaggaagctt agaaataggt aaggatgcag atatagctgt atttgatgag aatttagatt
    21241 gtaaaatgac actttgcttg ggggacgtag tatataaaaa tatatagtat acaaaacaaa
    21301 ctttaaagac agtaaaaaca atataaaaaa taataaatta aacttacatt agttaaagta
    21361 gtagttaaaa tttaggagga ataagatgag agtattagtg tgtaaagatt atgatggaat
    21421 gagtaaaaaa gccgctgaaa tgatagcagc tcaaatagtt ttaaaaccaa attcaatact
    21481 gggactagct acaggaagta caccagtagg tatgtataga gatttagtaa aaaaatacaa
    21541 tgataatata gtagattttt cagatgtgat gagctttaat ttagatgaat attataagtt
    21601 accaatatct aatgaccaaa gctatgatta ttttatgaaa gagaatctat ttaatcatgt
    21661 aaacataaag ctagaaaata ctcatctacc aaatggaatg gctgatgata ttgaaaaaga
    21721 gtgtctgaac tatgaagctt ctatagatgc agctggtggt atagatgtac aaatacttgg
    21781 aataggtcgt aatgctcata taggttttaa tgaacctgat actaaatttg caaaaagaac
    21841 tcatgtagtt gaacttacag agtctacaat agaagctaat gcaagattct ttaaatcaag
    21901 agaagatgtt cctaaaaaag ctgtaagtat gggaataggt tcaatattga agtctaagaa
    21961 aatattgctt ttagcttcag gagaagaaaa agctgatgca gtatataata ctgtttacgg
    22021 agatataact ccagaagttc ctggttctat acttcaactt cataaagaca ctatagttat
    22081 agtagatgaa gcagcagcaa gtaaactgaa tccaaaagat tataaattag tataagaata
    22141 gaatgtagtt taagtgaaaa atagctatca ttgaataatc aaatttattt aatgatagct
    22201 atttttattt aaatttttta cttcttttta tttaaattag ttattattgt ttaaattact
    22261 tgcttattac tttttacgaa aactcgttat caagaagtat ccgaataaga tgttaaaaat
    22321 tattatgttt agtgggattc tatcaagcat aataaaatta cctataattg ggatattacc
    22381 aattggaaac ataaagaaga atacaggcat cagtgatagt aaaaaagatg gaaaacaaag
    22441 aagaagtaat cttggaatat caatatacca actaccatcc tttttgtatt ctctaatcaa
    22501 taattcagtt cctagtaaca aaccaatacc accagaggaa attaaattaa taaaaatgta
    22561 tcttttaaag tcttgcatat aaccagtgtg aaattgagta tagaaatcat aatttaattt
    22621 aacggctaaa aaatacataa gcaatagaat gattaaaaat aaaagatatc taagagcttt
    22681 tttcatttta aattctccct tcagaaatac tttattcagt tttattttgt tggaatctga
    22741 ttttatcatt tagtttaaga aatccataat attagtgaag aatgaaataa gtattatata
    22801 tgaataaata tttttagaat taaggtgaac tgtagtgctt aatataacta taatattaat
    22861 tgtttgaata ttcaataaaa agtttaaaaa atatcaattt tgatataaac tgaataaata
    22921 cagttgaata ttaaattatt attttatcaa aaatatgcaa agtactacac cttcaaatat
    22981 cacctaaagt aattaaaagg caattaaagt gaagtagttc aagtatttct aaaatgagtt
    23041 taataaattc tataataatt tattttttgc cttaaaattg ccttaaaatc caaacaattt
    23101 taaaactaat gtactataaa aagctggtat aatttaaata tagtaaaaaa taagatttat
    23161 cttatctatt gggatttaat tatttaatca atatatttat accatttaat ttaaataaaa
    23221 agtttattaa ggagtgagct tatgagtaag ttaatttata tagcagatga tgaagataat
    23281 ataagaaatt tggtaaagac attcttaaaa aatgaaggtc atgatgttat ggattttaaa
    23341 acgggtgatg aacttttaga acaatttaat ataaaggagt gtgacttagt aatactagat
    23401 ataatgatgc ctggctcaag tggttttgaa gtatgtacaa aacttcgtga gaaaagtaca
    23461 gtcccaataa tcatgcttac tgcaagagat acagatatag attatattac agggataacc
    23521 ttaggtagtg atgattattt tacaaaacca tttagcccaa tgtctttggt tatgagagta
    23581 aaatctatat ttagaaggat agagtttgaa aagaaacaaa attatgataa atatagtaac
    23641 tcgatagata tggaattaaa atttggtgat gtaataataa ataaaaagaa taaaatcgtt
    23701 acaagtaaaa atgtaaatat agaccttaca ccaaatgaat ataatctatt gacttatttg
    23761 tttgaaaata tagatagagc agtttccaga gatgaattat taaacaaaat atggggatac
    23821 gatatagaag ttgagacaag ggctgctgat gatacagtga agagattacg taaaaaaatt
    23881 ttagatacaa atattttaat agaaactgta tgggggtttg gatttaggtt gaaggagaaa
    23941 agttaagatg aataatggaa atgacaagaa tagaattgga aagattaaat ccaaatttaa
    24001 attaaagttc tcaaagaaaa atataagcat aaaaactagg attttgttga gcatactttg
    24061 tttgataatt atagtattta tgataatatt agtatctttt aatgtatttc ttgatacata
    24121 tataaaaaca actgcgaatg aagaattgac gaagtctaca gaaatagtag aacatatgga
    24181 tagtaatttt agacctatta agccaccaca agatgatgga aagcttcctc ccaaagtatt
    24241 atctaatttt atgagaaatg tacaagataa agttaggatg gcagaaacac aatcagatgc
    24301 tgatgctatg gtagttgatt ctaagtataa cctgatattt ccaacaagag aggatgattt
    24361 cttaaaaaat gttgatgaga tggagctgat tagggagtgt attcaaaatg aaaaattaga
    24421 tttaaattca gatgaaaata cacggatatc taccagaaat aaggattatt atatttcaac
    24481 tgtaaaaatt actagtatat atggtgaaca agacaaatat cttatacttt ttatagacat
    24541 atcaaaaact ctaaatctag cacaaaagat aaatattgta ttaatatctg taatgtgttt
    24601 tgctggaata ttagcaatat ttacagctgt gattttatct gagaaaattg ctaaaccgat
    24661 aaaagagttg tgtgagtttg caaaaaaaat gggtcaagga gatttcaaaa gaacctactt
    24721 tgacttttca gataaagaat tagtagagct ctcaactgtt atgaataaga gtgctgagta
    24781 tctggataag tatgataatg aacaaaaaat attttttcaa aatgcatctc atgaattaag
    24841 gacaccactc atgtctatta aaggttatgc agaagctata aaatataatg ttatagatag
    24901 taaacatgca agtgatataa ttcttgaaga aagtgatagg ttaagtgata tggttgaaga
    24961 tttattatac atttctaaaa tagataatat aactaaagat tttgaacttg tagaatgtga
    25021 tttaagagaa gtactttcaa attgtggagc taggcaaaat gtaagagcta taaataaggg
    25081 gataaaattt atttatgaat ttgatgaaga aatggtttta tttgaatgtg atgaaaaaaa
    25141 catttccaaa gtatttatga atcttataga aaatgctttg agatacgcta agagtgaaat
    25201 aaaaatagtg tgtaagtata atcaaaaaaa tatagttgtg ataatagaag atgatggaat
    25261 tggaatcaag aaggaagatt tacctcatgt ttttgaaaga ttctataagg gagtaggggg
    25321 aaatcatgga attggattat caatagttaa atctattgta aataagcatg gtgggcgtat
    25381 atacgtagaa aatggcaaaa aaggagctaa gtttactata ttatttaaat tgtaaaaaaa
    25441 ttagagaaaa tataaagatg tttgaagttg ttttttatat atatctgttg tatactgttg
    25501 aaaaaagaac aatattaagc tgacatatat tacaataatt gacatttaaa gtaaatgctt
    25561 aaatatagat acgaaaggaa aagtaaaatc tgaagtgtat ttaggtttaa gtaagcttct
    25621 tattttataa aaaatatgta tgaaagaaca gctgattttt aatattacaa atttagtaac
    25681 ggttgtattt gaagcttttg tcatccatat gtttttatca gactttttag gtcagaaaga
    25741 agggtatata aaagttgtaa gatatgctaa attgggtttt ataatatgtt taggattctg
    25801 taatttaata actttaaacc ctaaaatcac aatgccttta atttttatcc ttattttttc
    25861 aacatcattt ttatataaag gaaatttaaa gacacgattg tttactactg ttttattaag
    25921 tatattcttt atactgtcag aaattgtagt tacaagtatt tttgttttat ttgtaaaaga
    25981 aggctttgaa ataatgtttg aaaataatag tataagagta ttggcgacaa ttttatctaa
    26041 aattgtcttt ttgttgactt gtaaaattat ttgtctattt aaaaaagatg tacatttaga
    26101 tatgcccata aagtattggc tccctttatt tttaatacct atatttagtt tatttctgtc
    26161 tgtttctatc tttgatgtaa gtaaattttt tagtcttgaa agtttaaaat ttctaagctt
    26221 aatatctagt gttggcattt tatatattaa ttttattgtt ttttatttat ttaaatttat
    26281 tatagataaa actaaactat ctatgaaata tgaaatactt gaaaaagaaa taattcataa
    26341 ggaagaatta agacttagta atgagtgtta taaaattatt gttgaacaga ctgattctgt
    26401 cgttttcgaa tggaatatca aagaaaataa atcatttgta tcgcaggctt ggactgaaaa
    26461 atttggatat aacaatgcat gtaagaatat ttttaaagaa attaaagata aagacttagt
    26521 tcattctgaa gataaagcta tatttgaagg ttttcttgaa agtattaaaa aaaagaatat
    26581 acacagtcaa gcagtatatc gtttaaaaaa atctaatggt gaatatattt ggtgtagaac
    26641 atcaattaca agcatttata atgatgaaaa tgaactttta agagttgtag gagtaattgt
    26701 agacgtagat agtgatataa aaaaatatga agagttaaga actagagcag aaagtgactc
    26761 attgaccaat atatacaata aaggtacatt tgaaaaatta gtggaagaaa ctatagttat
    26821 gaatacaggt gataaaaaag atgcattatt cattattgat ttagatgatt ttaaagaaat
    26881 aaatgataat tttggtcatc catttggtga ttttgtacta aaaacatttg ctgataagat
    26941 acaagctagt tttggtaata aagacttagt cggaagaatt ggtggagatg aatttgttgt
    27001 atatatgcaa gattatgtta cagaagtaaa tttgcataaa aaagctaaag aattaaatag
    27061 agtactttcg gataattaca ctgatttgag ttttagtttt gattcttctg tcagtatagg
    27121 tattgcaagg tatcctcaag atggaacttc attttttgaa ttgtttaaaa atgcagatag
    27181 agcactttat agcataaaag catcaggtaa aaattcatat tgtttatttg aagaagaact
    27241 atatgtacag tgaatttgaa tttagatttt atgtgagagt aagatttata tatacttgtg
    27301 gctgtctgat ttataaaata tgttactttg tatattttta tatgtttcag taaggttaat
    27361 taacataagc aaaggtgtaa gtaaatttat attagtttaa gtttacttac acctttataa
    27421 aaataaattt tgtaaattta aacagttggt tttataagga tttttattta ttttaatatc
    27481 ttagatattc ctttttgtat tccttagaga aaataaataa tgaaaggagt acagaaaaaa
    27541 ttaaacatcc taatatacca cttgaattaa gtcttaaagc attaaagttt aaaaaagcat
    27601 tatttaaatc ggtatccaaa agaaaaggat gctttgattt gctatatatg gaaaaattaa
    27661 aaatatattc ataatcaaat ttataaaatt aatatctttc catcctaaca ttatacattt
    27721 acttagatta attattatta taaaaataaa aatacaaata atagattcat ttacattctt
    27781 aaatgattaa agctctttac cctttaaaca tgcataacat atcgttataa ttccagtaaa
    27841 taagactaaa atgcccattc ctaaaattgc agtttcatca tctattactc caaatgcttt
    27901 taaagtaact tatttcgctt tgtataataa taatttgtct ctttttatat tttaacttct
    27961 gctgagattt gagttagata ttcgttagaa tctcgcacac ttatatcata tagaagatat
    28021 tcttcataaa caaaatcccc aatacgtaaa ttattctgat taaaaaaatt taataacttt
    28081 tcataagcct tgtaaatagt ttcataacta cctttatgat aagcagttac ataaagtccc
    28141 tttggtttga ttgatacagg atatttcttg tactctttat taacttttgt aaataaatat
    28201 gaatatgatt caaagtcttt attaattata tcttcacctt taatgattga gccaatcgta
    28261 ccatagtcac tcaattcata gttgtccata aagttaatac attcatataa aaaattttct
    28321 tcctcatctc ctaaaaactg ttctttatat gtaacaggtg ttttgaccaa gtactcttcc
    28381 tcatgttctt ttaaagtaat agtattcgca tctatattac aggcattttt agtgaatgaa
    28441 atagtagatt ccattagagc ttgaatatta tttagttttt caatttcatt tttaatatca
    28501 atggttttct tttctaaaag ctcaattagt aaattaggtg ttcttttgtc tatataagct
    28561 ttaatttctt ttaaaggcat ttttacttcc ctaagtgaag aaattatacc aaaaatgcta
    28621 agttgatggt atgagtagta tctatatcca ttttctttct ttaattctgg tgagaaaaga
    28681 cctatatcat cataatggaa aagtgttttt ttattgattc cacaaatctt tgcaaattct
    28741 ccagttgtaa aatatttttt tgaaacttga ctcataatta taattcctcc ttgactatcc
    28801 tgttacagta tagtttatca tagtattttg taaaggagtg tgattatatg aaaaaattaa
    28861 ttcatttttt aaaaccatat agagttttaa ttgttgtagt tttgatattt acgtttttac
    28921 aaacacttgg aactttgtat ataccaacac ttacagcaaa tatagtaaac aatggtgtag
    28981 taaagggaga tatagattat attgtaaaaa caggtttaat aatgatgata gtagctggta
    29041 taacagcttt atcagctgtg ttagtttgta aagtatcagc aaatctttca tctggatttt
    29101 gtagagatat tagagaagca gtatttgtaa aatcacaaga tttatcgata aatgatttta
    29161 ataatatagg tacagcatca atgattacta ggagtactag tgatattact ttaataggtc
    29221 agtctgtgtt tatgtttatt caattagtat taccagcacc aattataact gtttctggtc
    29281 tattcttagc atattctata gataaagcaa tgacaattat tattgttgta gtaatgtttt
    29341 tattcatgct ttcagcattt ttagttggta aaaagcttat aaagttgttt aaaatgatgc
    29401 aaataaagat ggacaatatg aatagggtat tacgtgaggt agtaactgga gtaagagtta
    29461 taagagcttt taatagggag cattttgaaa aaaagagatt tgatagaact gcaatagatt
    29521 attctgaaac agcaatttca ataaataaag tatttgcagt acttatgcct attgtaatgt
    29581 taataatgaa tttaggtata gtaagtatta tttggtttgg tgggatgaga gtcagtaatg
    29641 gaaatatgga gataggtcat ataatggcac ttattgaata ttgtatctta attttattct
    29701 atttaatcat gggagtaatg gtatttatgt acatacctag agcaggtgca tgtgcagata
    29761 gagtaaatca gatattagat atagaacctg aaattgtaga tggaaatggt cgtaaagata
    29821 ctgtctcaga gaggggacat ttagtattta aaaatgtaac attttcatat gcacaatcag
    29881 aagaacctgt gttaaataat ataacatttg aagcaaaatc tggagaagta actgcaatta
    29941 taggaagcac tggctcaggc aaatctacta ttgcaaatat aataccacgt ttttttgaaa
    30001 ttcaatctgg agaaatatct ataaatggtc aggatgttaa gaagattcct caaaaagaac
    30061 ttagagataa gattggattt gtgccacaaa aagctttttt atttagtgga acaatagaag
    30121 aaaatataag gtatggaaaa gaagatgcaa gtattgaaga agtaaagcat gctgcaagta
    30181 tagctcaagc tgatgaattt atttctgata tggaagacaa gtatgactca tttgtagcac
    30241 aaggtggaaa taatttgtca ggtggtcaaa aacagagaat atccattgca agagcgttag
    30301 ttagaaagcc tgaagtatat gtctttgatg atagtttttc tgcattagat tttaaaacag
    30361 ataaaagact tagaaaagcg ttgaaaaatg aaatcaaaga ttcatcagct ataattatag
    30421 cacaacgtat aagtacaatc atggatgcta atcagattat agttttaaat gatggaaaaa
    30481 ttgtaggtat tggaaaacat aaagatttac ttgaaaattg tgaagtttat aagcaaattg
    30541 cggattcaca acttagtaaa gaagaacttg cataaaatga agaattaatc tgatatttgg
    30601 aggtgtatga tatgagtgaa aaaagaatag atgaacaaga tatagaagta cttagttttg
    30661 aagatggcat ttcagcagaa aaagttaagg atgcaaaaaa aactactaag agattattaa
    30721 aatatatggc aaaacaaaag tttaaaatat taattatttt tatttcagta ttgataagtt
    30781 cagcgcttac agttttagca cctatggtta tgggaaaagc tattgaccaa ctatttaatg
    30841 gaataaaaac tgcagtccaa acaggtacaa aattcagtgt gaattttagt actatggggg
    30901 ggatagtatc aatacttcta gggttgtact taattagtgc agtatttata tatattcaac
    30961 agtatattat gtcaggagtt gcacaaaatc tagttcttag catgagaaaa gatttaagtg
    31021 ataaactcaa taaacttcct cttaagtact atgattctca taaaaagggg gaaacactta
    31081 gtatagtaac aaatgattta gaaaaagtag cagatagttt acaagaagga ttaatgcaac
    31141 ttattacagc agtagttaca gtagttggtt ctattgtaat gatgataagt ataagtgtac
    31201 cacttacaat agtatcagct ataacattac ttgtttcatt gggtattact gttgtaattg
    31261 caagaaaatc acaagaaaga ttctctgaaa atcaaaaggc actaggagag ttaaatagca
    31321 atatagagga gatatttact ggtcaaatag tggttaaagc atttagtaaa gaaaaggata
    31381 ctataagaaa ctttaaaata ttaaatcaaa atctttataa tgcaagtaga agagcacagt
    31441 tttcgtcata tgcaatatct ccaattatta gatttataaa cctaattggc tatgttatta
    31501 tagcagttgt aggtgggata tttgcatcaa ctggagcaat gactcttggt agtatacaag
    31561 cgtttattca atatgtaaat caagcatcag agcctactac agaaatatct tatattgtaa
    31621 atatgcttca agcagcaata gcatctgcag agagagtttt tacagttatg gatgaggtgg
    31681 aagagataaa ggatgaagaa tcttcaaagg ttattagcat gcctaaaggt aaagtacaat
    31741 ttgagcatgt taaatttgga tatagtgatg attttattct tatgaaagat attaatatca
    31801 atctaaatgc aggagataag attgcaattg ttggacctac aggagctgga aagacaactc
    31861 ttgtaaattt acttatgaga ttttatgaga tacaaggtgg aaggattact attgatggtg
    31921 ttaatataaa agatttaaag cgtggagaac ttagaactat gtttggtatg gttcttcaag
    31981 atacatggct gtttaatgga agtataaaag aaaatattgc atatagtaag tcagatgcca
    32041 caatggatga aattgtaaga gcagcaaaat cagcaagagt agaccatttt ataaggactt
    32101 taccacaagg gtatgacact atattgactg aggatgcttc taatctatct caaggtcaaa
    32161 agcaacttct aacaattgcc agggcaatac tttcagaccc atcagtattg attcttgatg
    32221 aagcaacatc tagtgtagat actagaacag aggtagaaat tcaaaaggca atgaataact
    32281 tgatgaaggg aagaactagt tttgttattg cacatagatt atcaactatt cgagatgctg
    32341 atttaatatt agtaatgaaa gaaggaacta ttattgaaca aggaagccat aaggaactta
    32401 ttgaaaagaa aggattctat gaagaacttt ataacagtca atttacaagt gaatatgatg
    32461 aagatgttgt atgattatca agttttaggc aactaaatga ttgataaata ttaagttaaa
    32521 tatagtaaca tgtaaggtta tatggaataa gagtatttct ctatttcata taaccttttt
    32581 tatttatcaa aataagataa aattttcttt ctaaattaga ttgaagaaag tatttatcaa
    32641 tataaaagta aaataatcat tattattagt gaagtaaata ttgtttgcca catatatgcc
    32701 ataaagatgc acttatttta cggagattta acaaagtagt gtaaagtata ctctaaatat
    32761 aaaataaatc aaatagagtt aaataaattg agaggtgata taaatagtga ataaaaaatt
    32821 gaactataga tttgaaatga agcacaaaat aactgaagca gatgtgttag ctttaaaatc
    32881 aagactctat ccaataatga agaaagatga aaatgcatct aaagatggaa aatatcttat
    32941 taggagttta tattttgata ctcctgaaga taaagcactt ttagataaat taaatggcgt
    33001 tgcaataaga gaaaagttta ggataagatt ttataataat aactgctctt atataaggtt
    33061 agagaaaaaa atcaaacatt acaacatgac atcaaagcta tcaactaatt taaccaaaaa
    33121 agaagtaata aatatactaa acaatgatat tgaatttcta aaagagtcga caaattgttt
    33181 attaagagaa ttttatttga aattaaaatg tgaaagatta gaggcaaaaa gcatagttga
    33241 ttacaataga gaagctttta tttatccagt tggaaatgta agagttacaa tcgatagtga
    33301 tattaaaact tctgtaaatt cgatagattt atttaataaa gatttgccga ctgtttcggt
    33361 aattgatgag aatatgactg tattggaggt taaatatgat gaatttatac cagattttat
    33421 aaaggattta attcaaatta ataagactac ttctacagca gtttcaaagt atgcttcaag
    33481 tagattatat atttaagaat aaaggctatg atttatataa agatatacat aaataaggtt
    33541 aaaaaacaaa taggttaaaa ataaataaaa taaaaaataa ataagttaaa aataggaagg
    33601 atgattttaa ttatgacatt taatgatatt tttaaatcaa gttttataga aaacgtatca
    33661 ggtttttcat ttgtggacag tgctttagca ctaggttcag cttttttagt aggtttgttt
    33721 atatatatgg tctataaaaa gacttatatg ggaattatgt attctcgacc attcaatgtg
    33781 tcgcttgtag cacttacaat gcttacaact tttgtaatat tggcggttac ttcaaatgta
    33841 gttttatcct taggtatggt tggtgcctta tctatagtaa gatttagaac agcaattaaa
    33901 gacccaatgg atttagtatt tctattttgg tcattgggtt caggtatagt tttaggagca
    33961 ggtttgattc ccttagctgt catgggttca ataattatgg gattgattct aatattcttt
    34021 tcaaataaaa caatatctga aactccatat atattgatgg taaattgtaa taatgaagat
    34081 tcagaagata tagcaactga taaaattaaa aaagtattta ctaaatatca aataaaatca
    34141 aaaagtgtta caccagaaaa aggaatagaa ttagtgtttg aagtaagaat gaaatatgga
    34201 gagacaagtc ttataaatga cttgagtcaa gtagatggag ttactaatgc agttcttgta
    34261 agctataatg gtgactatgt agcatagaga ggagtaatct tttatgaaag ataaaaaatt
    34321 tacccttctt atctctatta tgattatatt tttatgtgct gtagttggag tttatagtac
    34381 atctagcaac aaaagtgttg atttatatag tgatgtatat attgaaaaat attttaacag
    34441 agacaaggtt atggaagtta atatagagat agatgaaagt gacttgaagg atatgaatga
    34501 aaatgctata aaagaagaat ttaaggttgc aaaagtaact gtagatggag atacatatgg
    34561 aaacgtaggt ataagaacta aaggaaattc aagtcttaca tctgtagcaa atagtgatag
    34621 tgatagatac agctataaga ttaattttga taagtataat actagtcaaa gtatggaagg
    34681 gcttactcaa ttaaatctta ataactgtta ctctgaccca tcttatatga gagagttttt
    34741 aacatatagt atttgcgagg aaatgggatt agcgactcca gaatttgcat atgctaaagt
    34801 ctctataaat ggcgaatatc atggtttgta tttggcagta gaaggattaa aagagtctta
    34861 tcttgaaaat aattttggta atgtaactgg agacttatat aagtcagatg aaggaagctc
    34921 gttgcaatat aaaggagatg acccagaaag ttactcaaac ttaatcgttg aaagtgataa
    34981 aaagacagct gattggtcta aaattacaaa actattaaaa tctttggata caggtgaaga
    35041 tattgaaaaa tatcttgatg tagattctgt ccttaaaaat atagcaataa atacagcttt
    35101 attaaacctt gatagctatc aaggtagttt tgcccataac tattatttat atgagcaaga
    35161 tggagtattt tctatgttac catgggattt taatatgtca tttggtggat ttagtggttt
    35221 tggtggaggt agtcaatcta tagcaattga tgaacctacg acaggtaatt tagaagacag
    35281 acctctcata tcctcgttat taaaaaatga gacatacaaa acaaaatacc ataaatatct
    35341 ggaagagata gtaacaaaat acctagattc agactattta gagaatatga caacaaaatt
    35401 gcatgacatg atagcatcat atgtaaaaga agacccaaca gcattttata cttatgaaga
    35461 atttgaaaaa aatataacat cttcaattga agattctagt gataataagg gatttggtaa
    35521 taaagggttt gacaacaata actctaataa cagtgattct aataataatt ctaatagtga
    35581 aaataagcgc tctggaaatc aaagtgatga aaaagaagtt aatgctgaat taacatcaat
    35641 cgtagtcaaa actaatacag ataatgaaac tgaaaataaa actacaaatg atagcgaaag
    35701 taagaataat acagataaag acaaaagtgg aaatgataat aatcaaaagc tagaaggtcc
    35761 tatgggtaaa ggaggtaagt caataccagg ggttttggaa gttgcagaag atatgagtaa
    35821 aactataaaa tctcaattaa gtggagaaac ttcttcgaca aagcaaaact ctggtgatga
    35881 aagttcaagt ggaattaaag gtagtgaaaa gtttgatgag gatatgagtg gtatgccaga
    35941 accacctgag ggaatggatg gtaaaatgcc accaggaatg ggtaatatgg ataagggaga
    36001 tatgaatggt aaaaatggca atatgaatat ggatagaaat caagataatc caagagaagc
    36061 tggaggtttt ggcaatagag gaggaggctc tgtgagtaaa acaacaacat acttcaaatt
    36121 aattttaggt ggagcttcaa tgataataat gtcgattatg ttagtaggtg tatcaagggt
    36181 aaagagaaga agatttataa agtcaaaata agattaaaat tgaatataaa taattttaat
    36241 actgttaagt ctaaatattt acttagcagt atttttttag aaaataatgt gtttgattaa
    36301 taatataagg taataaattg ataaaaatta aatacagcat attaataata cataataaag
    36361 taataaaaaa actgtttaag tataataact tatatttaga cagttttttt catttataaa
    36421 taatataaat gaaattgaaa acatttgaag gatagaaatt ggttggataa atgtataaat
    36481 tacttcacca aaaaataatg acaagagttg taactaagtt gtaataaaat ggtagttatt
    36541 tagcataaaa taatgtatca tagaagtata ttataaaatt aataaaataa gatttttgta
    36601 agaaaactgc tggcttttga tatttagagt gagtagttaa attatgttta ggaggggtag
    36661 aatttgttgc aaaaagtatt atggaaattt ttaaagctag tagtcggttt atttatatgt
    36721 tcagttggta tagtattgac gataaattgt aaccttggat tatctccctg ggatgtattt
    36781 catcaaggac tttcaaatca tataggaata actataggaa ctgcttctat aattgtaggc
    36841 tctatagtag ttattgctga tgtcgttctt ggagaaaatg taggatgggg aactgttttt
    36901 aacatgctac taattggatt ctttatggat ttacttttat atagtaattt aattccagag
    36961 gctgatagtt tatttgtagg aataattatg ttgatattag gattggttct tttgtctgtt
    37021 ggaatggtat tttatatggg aagtggttta ggaagtggac ctagagatgg tttgatggtt
    37081 gcaattcaaa agaaaacagg aaaatcactt aaattaataa gaggtactat agaagttgga
    37141 gcattaatag taggattttt attaggtgga aaagttggta taggaactat aataagtgca
    37201 tttggattgg ggtatttcac acaaatggta tttggcttat ttaaattaga ttgtagtaag
    37261 attaaacata gatttatagt agatgatata aaatttatca aagtgtatat gagtggtgag
    37321 aaaaaagcta ctgttcaaaa tatagttaag taatttaaga ataaattcaa cgaaatgtta
    37381 agtattttaa attaacattt tgtttagatg gataaattga atattaaaag aatattaaaa
    37441 tatgaggatt gctagaacac tataaaatat agatttctag caatttttta tttgttcaat
    37501 gtttttttag tactagaagt cttattctct atttaatgaa tgaattaatt tataattaga
    37561 gatactaaac tttatagata ttaatataaa cacctttaaa ctgtgtattt tccaaagcct
    37621 ttaaaatgct tgtatttatt ctaaataaaa aaataaaaaa atgtcaaaaa aactcttgta
    37681 ttatatccaa attttatata taattaccta tgttgtttag aaattttaaa ctcaatgttt
    37741 agtaaacaaa atgtttagta aaataaaaca gaaactagga ggtgcaacat ggatataggt
    37801 gaaaagataa aaagattaag aacagaaaaa caactgaccc aggaagagct agctaataga
    37861 tgtgaattgt caaagggatt tatttctcaa ttagaaaata acttaacatc accatccata
    37921 gctaccctta tagatatact tgaaatacta ggtacaaatt taagggaatt ttttaatgaa
    37981 atagatgatg aaagaatcag ttttacaaaa gaagatatgt ttgaaactga agatgaagat
    38041 ttaaaatata aattaaagtg gttaattcca aattcacaaa aaaatgaaat ggagccaata
    38101 ataataacat tgtatccagg aggacagtat aaagaagaaa agccacatga aggtgaagaa
    38161 tttggatatg tattagcagg ttcaatatat gtccatatag gcgaaaagaa aaataaagta
    38221 aaaaaaggag agagttttta ctttagacca aaagcaaatc actatatatc aaacgaaggc
    38281 aaaactacag caaaagtgat ttgggtaagt acgccaccat cattttagaa tagaggtgtt
    38341 taataattgg tagaaaatat aatagaatta agggatatat ctaaacatta tgaggaactt
    38401 actgttttag ataatttcaa tttagatata aagaaaaatg agtttttaac attacttgga
    38461 ccaagtggat gtggaaaaac tacaacatta aaaataatag caggatttga gtatgctgat
    38521 gatggtaaag ttttatttga aggtaaggag ataaataact tgccaccata tgaaagacaa
    38581 gtaaacacag tatttcaaaa atatgcttta tttccacaca tggatgttta tgaaaatgta
    38641 gcttttggat taaaaattaa aaagactcca aaagatgtaa tagatgctaa agtaaaagag
    38701 gttttgaaac ttgttgcact agaaggtttt gaaagacgac aagttgaatc attgagtgga
    38761 ggacaacaac agagaattgc aatagcaaga gctctagtca atgaaccaaa ggtattatta
    38821 ctagatgaac cacttggagc acttgattta aagttaagac aagagatgca aatagaatta
    38881 aagagaatcc aaaaaaaatt aggaataaca tttgtttttg taactcatga ccaagaagag
    38941 gctcttacta tgtcagatac tattgttgta atgtataagg gcaaaattca acaaatggga
    39001 acaccacaag atatatacaa tgaacctaaa aattcatttg tagctaaatt tataggtgaa
    39061 agtaacatat ttgatggaat tatgatagaa gattataaag ttaatttctg taatagagat
    39121 tttgagtgtg ttgataaagg attcgaaaaa aatgaaaata tagaagtagt aataagacca
    39181 gaagatataa aaatggtaaa gccagaagaa ggaatgttaa aggggaaagt tacatctaca
    39241 gtgtttaaag gagtgcatta cgagatagaa ttgaatgaaa atggaagatt gtggatactt
    39301 cataatacca aaaatgctga ggttgggact gaactaggca tggatatata tccagaagat
    39361 atccatataa tgagaaaaga gaataactaa gatgaaaaga aaatcttttt tagcatatcc
    39421 atatgtagtt tggagtgcga tatttgtaat aattccttta atattagtgg tattttttag
    39481 ttttacaaaa gaatcaggtg gaggttatgc ctttacactt gagaattata aagaagtaat
    39541 tgaccctata tatatgaaag tttttgggcg ttctattctt ttagcaggag gagctacatt
    39601 aatatgcctt atagttggtt atccagtggc atatataatt tcaaaggctc gtgtaagtag
    39661 aagaggttca ttaatattat tgtttattct tcctatgtgg atgaactttc ttttaagaac
    39721 atatgcatgg gttgctatat taggaaaaaa tggactttta aatacatttt taggttggtt
    39781 tggaatacaa ccattagcaa ttttgtatac taattttgct atacttttag gtatggtgta
    39841 taacttttta ccatttatgg ttcttccaat atatacagca ctatcaaaga tggataatga
    39901 tttgataaac gctgctcatg acttgggtgc aaataatatg acagttttta gaaaaattat
    39961 atttcctttg agtttgccag gtgtaatgtc tggaataact atggtattta tgccagcagt
    40021 cactactttt gcaatatcaa gactgttagg tggaggtaaa ataatgctgg ttggagattt
    40081 gattgaacaa cagtttacag ttgttggaga ttggaacttt ggttcagcta tatcgatatt
    40141 tatgatgata gtaatattaa tatctatgtc tataatgtca aaatttggag atgaatctga
    40201 caaagaaggc ggtgggttac tattttaaaa ttaaagaaaa taacttctaa tatatattta
    40261 gcattagtat tcttattttt gtatgcaccc atatttgctt tggtactatt ttctttcaat
    40321 gattcaaaat caatggcaag atggaatgga tttacatgga agtggtatgg tcaattactt
    40381 caaaatgaga gtataatgag tgctttatat tatactattg taatagctat attagcgtct
    40441 gtaatatcta caatagtagg aactataagt gctataggaa tacataagat gagaggtaag
    40501 agtaagaaat taatactaaa tgtaaactat cttcctattt taaatacaga gatagttaca
    40561 gcagtagctc ttatgagtct gtttgtattt gtaaaaatgg aatttggatt tacaacaatg
    40621 ctattggcac atataatgtt ttgtttgcca tacgttatac tttcagtttt gccaaaaatg
    40681 aagcaattac ctgataatat agaagatgca gctatggact tgggagcaac acctatatac
    40741 gctcttagaa aagtaatttt accacaaata aaaccaggta tagtttctgg atttttaatt
    40801 gcatttacta tgtcaataga tgactttata ataagtttct ttaatgctgg aaatggtgta
    40861 agcaatcttt ctatagaaat ctatggaatg gctagaagag gtataaaacc tgaaataaat
    40921 gcattatcaa caataatgtt tgcagtggtt ctaggtttac ttttactagc taataaaaaa
    40981 gaatctatag taagggggat taaataatga ttaagttaaa aaaaacaata tcccttatag
    41041 ctgtaggtat gatgacagtt actttattta caggatgtaa taaagcaact gattctacaa
    41101 aagttttaaa tgtatataat gttggagatt atatagatga gtctcttata gataagtttg
    41161 aaaaagaaac aggaatagat gttcaatatt caacttatga tactaatgaa atgatgtatc
    41221 aaaaagtaaa gagtggtagt acacactatg atttagtatt tccttcagac tatatggtag
    41281 agaaaatgaa aaatgaaggt cttttggaaa aattagattt taagaatata cctaatatga
    41341 aatatttaga taagagtttt ttaaatcctg tatacgacaa aactaatgaa tatagtgttg
    41401 catatatgtg gggaactctt ggaatattgt acaataagaa agaagttaaa gaccctatgg
    41461 atagctggaa tatactttgg aatccaaagt ataagggaaa tataatgatg tttgactctg
    41521 ttagagatac tatagggata actcttaaaa aattaggata tagcatgaat agtgtaaatc
    41581 caaaagaaat aaatgaagct aaaaatcttt taatgaaaca aaaggattta gtattggctt
    41641 atgtaaatga tgaaggtaag gatagattgc ttggtggaga agtggcaatg ggtatgctgt
    41701 attctggaga tgcagttacg ctaatggagc aaaatcctga ccttgattat gctataccta
    41761 aagagggaac taataaatgg gtagatgcta tgtgtgtacc tacaacagca caaaataaga
    41821 aagaagctga gctgtttata aactttttat tagacccaga gaatgcaaaa gtaaatgctg
    41881 agtacattgg gtattcaaca cctaatacag gagcactaaa attattagac ccagaaataa
    41941 ctcagaatcc tgttgcatat ccatctaaag aagtacttga taaatgtgaa acttttgaag
    42001 atattggtga aaatataaaa ttatatgaca aggcttggat agagttaaaa tcaaaatagg
    42061 gtcttgttgg tttaagtaaa tttacttaat aaatacttaa taaaactgtt cttttttaga
    42121 aaatttattt tctaattatt gaacagtttt attttttgtt taggtcatgt ttttattttg
    42181 agtttatttt tatgagaatt taaagtacag taagtttcat tgattactat ttttataata
    42241 ataactataa agaggttgtc tcgaaattga gataagcctc tttttcattg ttgaaatgat
    42301 gaaaacatgt ttgatttcat aaaaaaagag tgattcatga gctaaagaat ttgctttgag
    42361 acagtatttt ttattaagtt atattcatat gcaatttaaa tagtttatta ataaatgaaa
    42421 acttatttgt ataatgactt taataataat tagaaaaaat gggcaactta atagaataat
    42481 tggaggtgta aatttataaa aaatgaatag gataaataaa aaaatagatt tattaatatt
    42541 ggctttgctc gtttttatat ttttaattgt tggaatagta atactatcga ttaggacaga
    42601 aaataaattg aatgtgttca taatgttagc aataattttt tttataataa tgttaactta
    42661 tttatcaaat tcagtagtgg ggttgataac aagttcaata attatattta tgtatacatc
    42721 ctatatttta tataacaata ttactcacaa tatggatgtt gaatttatat catatatgtg
    42781 gataatagca acaccagtat cttcaattat aatgggtaat ctgaacaaaa gcataaatga
    42841 attgcaaaat acaaataaaa aactatctga acagtataag gaattagtga ctattgatag
    42901 tgaaactgga cttagaaatt taaagatttt ttataatgat gtaaatatgg agataagtaa
    42961 atctattaga cataatactg atttttctct tatgatagta aaattaccat actacggaaa
    43021 cctacagact atatttggtg aaaacaaaac taataaaata gtaaaatata ttggttcaaa
    43081 tattatagaa tgtacaagaa atgaagatat aatttatagt ttacaaaaag atatgatagg
    43141 gatactaatg ccaaatacat ctttggaagg ttcgaaagtt gttaaagaca gaataaagaa
    43201 aaggataaaa gaattaaact tagatttaaa caatagggga aaatatgtaa atatagatgt
    43261 caaaattgca tttttacaat ataagagtag ttttggagat agtataaatt ttaagaatat
    43321 agttgaagag gaacttcaat atgatgttta aaatatttaa taaaagtcta ttaaaattag
    43381 tagttgtatt atcaatagta ctgacaatat caaattttag cttatcttca tatgcatcag
    43441 aaattacttc cagcacagat aaggtattaa tcatatatga ttctaagaaa gaaacagctt
    43501 ataatagaga tattttaaat attatgagaa ctctattggg aagatttagt tcagatatag
    43561 agctattaaa attgagtaac tatgatggtg agataaataa aaattattac agtcatatat
    43621 ttattttagg aatcaatgaa aactcatata ataatgataa aaacactaaa aacttgatta
    43681 gttccttaaa ttcatataaa ggaactatat gttggttagg atatggtata gaaaatcttt
    43741 tggaacataa aaaatacaat ttagactatg taggaaaaac aaacaatata gttagtgtaa
    43801 attatagagg taaatcatat aacttggatg aacattatgt ttttaacatt gtagaatcaa
    43861 aagatacaag taataaagta ataggaagta ttaatgatac cttaaataag tatccatata
    43921 taataaatga taaaaatctt ttttatgtat caaaattaga tttagatgga gttttatttt
    43981 atatattttg cgattcactt aatgatattt ttaatattaa gacgtttgat aaaggacgta
    44041 tatttgtaag aatagaagat gtacatgctt ttagagaacc aaaaaatctt gtagagatag
    44101 cggattattt aagtagtaag aatataccat ttacgattgc attaatacca gcatatgtaa
    44161 atcctaaaaa tcataaagta ataactttat cagaaagccc tgaaattgtc aaagcaataa
    44221 aatatatgca agataaaggt ggaactgtga tattgcatgg atatactcat caatacaaga
    44281 aagaagaagt ttctggagaa gggtatgaat tttgggatgg taaaaaagat gaacccttaa
    44341 aagaaaatat gaagatattt gtcaaagata gagttttgaa tggtcttaga gtatgtatag
    44401 agaatggaat ttatcctctt gcatttgaag cgccacatta tgcaatggaa tcagagggat
    44461 ataaagaatt aaaaaaatat ttttctactt atatggggca acatcaaaat aatgataaaa
    44521 aatttagcac aaatacatat ccttatatta ttagggatac agaggagttt aatatattta
    44581 tacccgaaaa tttaggatat atagacccag aagataagtt tacttttcaa aatataaaag
    44641 aaaatttaaa taaattatct attgtaagag gttttagtgg agggttcttc tttcattcat
    44701 atttaaacat agagtatcta aaaaacacaa tagaatattt agaaaaacag aatatagaat
    44761 ttatgaattt aagagatttt aataattggg taaaagttga tgaaatacaa ataagaaata
    44821 atggagatga aattatagtc aactatgata aggacttaga tgaaataact aaaagtgata
    44881 ctagatttaa atccatatcc aatattagta aaattttaat attcatagta tctataagtg
    44941 ttttaatatt tgtgattata tttatatatt ttaagagaat agataaaaag aaatttttaa
    45001 aataaatgat tttatattag aatcaatatt ttaaaatatt ttaggagaaa tttatgagag
    45061 atttaaatgt atcagagtat ttgttcgtat ttagtctgtt tagtatatgg tctttattgc
    45121 ttataaatat tattttagct atgggtggat atatatttta ttttaaaaac tttgataaag
    45181 aaataaaaga aattgatgaa tatcctatga tatcaatact tgttcctgct cataatgaag
    45241 ctaaagtgat aggtagaact gtggagtctt tgttattact caattatcct aagagtaaga
    45301 tggaacttat tgttataaat gacaattctt ctgataatag taaagaaatt ttagaaaata
    45361 taaaggatag gtacaacaat tataatttca ctataataaa tacagatagt ttaacaggtg
    45421 gaaaaggaaa gtctaatgca ttaaatattg gatatacgat ttcaaaagga gattttatag
    45481 ctgtttatga tgcagataac acaccagata aaaatgcact tagatatcta gtgcaaacta
    45541 tagtaatgaa tgatgaatta ggtgctgtta ttgggaaatt taggactcga aataaaaata
    45601 aaaacctatt aaccaaattt ataaacatag aaacattaag ctttcaatgg atgtcacaag
    45661 ctggtagatg gcaacttttt aatctatgta caataccagg aactaacttt atattgagga
    45721 gaagtatcat agaagaaatt ggaggatggg atagtaaagc aattgcagaa gatacagaaa
    45781 taagttttag gatatataaa ttgggataca atataaagct tgtaccacaa tctataacat
    45841 gggaacaaga gccagaaact gttaaggtgt ggataaagca acgtactaga tgggcaaaag
    45901 ggaatatata tgtattaatg aaatatataa aaaatatatt taaacaggga agaaataaga
    45961 ttgtatttga tatagcttac tttttttctg tatattttct atttttaaca tctgtaatta
    46021 tatccgatat tttatttgtt ttaagtatat ctaaactagt agaaatttct attccaatta
    46081 acttttttct aatatggata ctatcttatc ttttatttat tatagaagtg agtataagcc
    46141 ttactataga aaaaggtgaa gcaacaattg aaaatatatt catagttgca ataatgtatt
    46201 ttacatactc tcaactatgg ctgtttgtag ctataaaagg aatgatagag tatctaaaag
    46261 atataatttt taaaagagag gttaaatggt ataaaacaga aagattttga ttcatgtaca
    46321 ggaggaatta acatgaaaaa atttattata tcaattatat ctttagtatt gtttttttca
    46381 aatatatcac ttatatacaa agtaaatgct gatgagacta aaattaaaaa ttataagttt
    46441 gaaagagata taactattga tggtgttata ggaagtaata gtactttttt tgaagtaaat
    46501 aaaaattggg atattgaaga agttttattg catcttaatt ttagtaagag ccaaatatta
    46561 aatggagatg tttcaagttt aactgtattg ataaataatg taccaataaa atctattaaa
    46621 ttaaatgcta agacaaatta taaaaataca ctagaagtat tagttccaaa agattatata
    46681 attcaaggat ataatgaaat aaaaataaaa acatacaaaa caatatctga taaaatttgc
    46741 caagatgatt ccaatactgg gaactggatg gttattcaca aagaatcata tatatcaatt
    46801 agatataagc agaaaaaggt ggaaaactca ataaatgaat atccgtatcc atatgcagaa
    46861 attgaaaata atcataaatt agatacaact atagtagtac cagataatat gactagagga
    46921 gagactacag cagtgtttaa tttggcatca gcatttggaa aaataacaaa aaatgatgat
    46981 ttaaagttag atgttaaatt atattcagaa atgaaaaatt ggtcagatga taatattata
    47041 tatattggta aacctgaaaa tacagcagaa gaaattttgg atattttaag tataaaggaa
    47101 caaaccctat tatcttcaaa ctgtataatc aagcaagtag attcaccata caataagaat
    47161 aagaagatga tggtggtaat tggtagtaat gaagatgatt taataaaggc atcaaattta
    47221 ttaatagaaa atagactttc taaccaagtt ttatcatcat cagtgcttgt aaacaaagag
    47281 actaatataa aaattaatag ggaacaaaaa ttaaatttag gtcatttaac attaaaagac
    47341 ttaggatatt ctgacttttt gttggaagga gcatttaatc aacaagcttt gtttgatgtc
    47401 aaaataccaa cgggtaaggt attagatgat ggttcaaaga ttatcttaaa tttaagatat
    47461 tctgacaatt tagattttga aaaatcttta gttacagtgt ctataaatga tgttattgtg
    47521 ggaagtaaaa aattggatag gtcacattct aataatgata agctagaatt aaaaatacct
    47581 aaagatatag ataataaaaa ctattatcaa gttaaattga catttaattt gagtataaaa
    47641 aattcgaatt gtgttactag agagagtaat aatccttggg catatgtatc aaataattct
    47701 tatttggcgt tatctacgaa agaaaatgaa accttatctt ttgaaaatta tccgtatcca
    47761 tttgttagag atgatgagtt taatgattta actgtgataa tgccagatta ttcagggtca
    47821 caagctatga cctggatgtt tagattaggt gttactttag gtgcgaatat aaattcacat
    47881 aatggaaata taaatgtaat tagaggaaaa gaatttagtg acaagtataa ggatactaat
    47941 attgtagttt ttggagtgcc acataataat tctgttataa agatgttaaa taataattta
    48001 aatataaagt tcgataaaaa ttactccaat tttatatcaa atgataagat aagctttatt
    48061 gatgattatg gaaaaaatat ttctaccatt caattaataa aatcaccata taataatcaa
    48121 aaaaatatca tggtaattag ttcaatgaat gaaaaaaact tatatttagg aatggattat
    48181 ttgttgaata aaagtaaagt taatgattta aaaggagata cattgataat tgatgaatac
    48241 ggagaggtag aagatttagc ttataattta aaacctaaga aagaagtaaa agattcaagc
    48301 tggaatatga gtataaataa gacaactaaa gtatttttaa tgatttcttt tattactata
    48361 attgtagcca tgatattatc aatgctatat ataaaaaaat ataaaagaag ataatatgat
    48421 aaatttatta ttttaaaaga ggtatataat ttgaggaaat atatgaataa atttaaatta
    48481 aaaagaagta ttttaatctc attaataatc ttaattttta tatttatagt ttactttgta
    48541 agtattgagt taaaagatag gagtctagta aataatcaat ataaaggtaa gattaaatcg
    48601 gccaatttat ctgtagatta tgaaataaat caagttatga aggatataga taaattggga
    48661 ttgaatacag taaatgtacc tataattata aatgtagagt ccattaattc tgatattatg
    48721 tcaatagata ataatagtaa agaaaaggca attaagttaa taaaaaaatt aaataaaaaa
    48781 ggtatttcaa caatattaga ggcatatcca tggattgaaa atggaaaatt gtatgagact
    48841 gactggaacc ctataaataa aaaaagattt ttttatactt ggcaaaatgc catattaaat
    48901 gaacttataa ttgatgtagc aaatccactg gatgtaaatg ttttaaatat tggttctaat
    48961 tttgtacact tggaagaata tcaacaaaat tggggtgaaa taatagattt tgtacaatcc
    49021 aaatttgatg gtcttgtaac gtacagaact aattggtggt atacaaaaaa agatgattca
    49081 agtagtaagt tgttttatga acaaaaattg aacaataatt tttttgataa gttagatttt
    49141 atatctatag cagcatattt tgagttaagt aataaacctg ttaatacagt ggatgaatta
    49201 atttctgcct tacactcatc tactgtaaac aatagaggac aaaatataaa acaagaaata
    49261 tataaccttt ataaagctca tagaaaacct atattttttg gagaattagg tttttcaaat
    49321 agagaaagtg caagttctca gccgtggaat catactcctt caaaagctgt aaatggcgaa
    49381 gaacaagcaa ggtgttttga ggcatataag aaagtttttg aaaatgaaga ctggataaat
    49441 ggtttttctg tgttttgtgt aggtaaaata gatgacgaaa aaatttttta cccatcaaaa
    49501 gagagtataa aagttattaa gtcttggtat gaataatttt aaaagtgtag aatttatata
    49561 gattaaatag atgattagga gagatataaa tgaatgacat caaggttatg actgtatttg
    49621 gaactagacc tgaagctatc aaagtagcac ctttaataaa ggaacttgaa aaaagagaga
    49681 atataaaaag tattgtttgc gttacagctc aacatagaga aatgcttgac caagttatag
    49741 aaaccttcaa tataaatgta gactatgatt tggatataat ggaaaaagga caaagcctga
    49801 atgatataac atgtaagatt ttaaataaac ttcccttgat tttaaacaag gaaaatccaa
    49861 atataatatt ggtacatgga gatacaacca caactctagc tacaagtttg actgcatttt
    49921 ataataaaac tcttgttggt catatagaag ctgggcttag aacctatgat aaatattctc
    49981 cttttccaga ggagttaaat agacaactta caggtattat tgctgatatg cactttgctc
    50041 ctactaattt ggctagaaaa aacttgattt ctgaaggaaa atttaataat aatatatttg
    50101 taactggtaa tactgctatt gatgctttaa agatgacaat aaaagaaaac tataatcatc
    50161 ctataattga tgagattggt aacgatagga tgattttgtt aacctctcac agaagagaaa
    50221 atttgggtaa acctatgaaa aatatattca gagctataaa gcgaatagta gatgactttg
    50281 aagatgtaca gatagtatat cccatacatt taaatcctaa aatacgaact atagctgatg
    50341 agatatttgg aaaatttcct gaaaaaattc atattataga gcctttagat gtagctgatt
    50401 ttcataactt tttaaataaa tcttatatga taatgactga tagtggagga atacaggaag
    50461 aagctccatc attaggtaag ccagtccttg tgttgcgtga taaaacagaa agaacagaag
    50521 gaattgaagc aaaaacactt aaattagtag gtactaatga agatagaata tataattcag
    50581 tgagcgattt attaataaat aaagataact atgttcagat gagtaaagca tctaatccat
    50641 atggagatgg aaatgcaagc aaatatatag tggatataat aattaaaaga tttaattgca
    50701 aatatttaaa ttagataagg cctaaaacat taactaattg atataagatt tatgataata
    50761 ttaaggaata caatttctaa gggggagtaa tatggctaga aaattaataa aaaatttagg
    50821 taaaagtaaa agtgtaaaga gagtgaaact tttatttaag aagattttta ttactgtatt
    50881 catagtagca agtatagttg ctatttttaa tataacgaaa tattttgagg aattatacaa
    50941 agtaagggat ttaaaaagta ctaaaattga atactatatg gatgtggctg atgaagcagg
    51001 agatggaaag gtccaattaa gttggaaggc cttacttgct atagacatgg taatacatga
    51061 tgaagattta agtaatataa aaaagaaaga cacattggat ataggggaaa agtttatagt
    51121 agaagataaa aatgataaag gcgaaaaggt gtataaggta aaaaagttta ataaggtatt
    51181 aagcgaattg aaatttgact cttctcaaaa aagtagagca agaaaataca tgaaagattt
    51241 ggaatacaca taccttggaa ataaacaatt agatagtagt gaagaaaaaa ttaaatttat
    51301 aaagaagtta gaagactcag ctataagaga atatgttgat tatggaatat tgccctctat
    51361 aacaattgga caagctatat tagaatctgg ctggggaaat tctaaactta caaaacagag
    51421 taataattta tttggtataa aagcagataa agcatggaaa ggaaaaagtg tagaaatttc
    51481 aacttcagag cattataatg aaaaaattgt agctagtttt aggtcgtata attcattaca
    51541 agattctgtc aaagaccaca gtttattttt aattaataat aaaagatata gaaaacatgg
    51601 gttgtttgag gcaaaagatt atattagtca agctcaagca ttagaaaatg cagggtatag
    51661 tacagcagaa gataaaaaag gaaatcgtat atatgcagag ctattaatag atgttattag
    51721 gagttataat ttgcaattga tagacaataa agttgagaca aaataattgt taactttata
    51781 tgaggagata acaagataag attcttttct acaaaaagaa tagaaaaatt gtaaaaaaaa
    51841 ctaaaaaaat gtattgactt gttatttaaa aggtgatatt attattactg tactcgaaag
    51901 agaacaaaa
//
LOCUS       DACTZW010000024        49048 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.024, whole genome shotgun sequence.
ACCESSION   DACTZW010000024 DACTZW010000000
VERSION     DACTZW010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 49048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49048
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.024"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            18..92
                     /locus_tag="JAM15_07120"
     tRNA            18..92
                     /locus_tag="JAM15_07120"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:50..52,aa:Gly,seq:gcc)
     gene            117..193
                     /locus_tag="JAM15_07125"
     tRNA            117..193
                     /locus_tag="JAM15_07125"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:151..153,aa:Arg,seq:tct)
     gene            203..278
                     /locus_tag="JAM15_07130"
     tRNA            203..278
                     /locus_tag="JAM15_07130"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:236..238,aa:Gln,seq:ttg)
     gene            287..362
                     /locus_tag="JAM15_07135"
     tRNA            287..362
                     /locus_tag="JAM15_07135"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:320..322,aa:Lys,seq:ttt)
     gene            365..453
                     /locus_tag="JAM15_07140"
     tRNA            365..453
                     /locus_tag="JAM15_07140"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:399..401,aa:Ser,seq:tga)
     gene            457..532
                     /locus_tag="JAM15_07145"
     tRNA            457..532
                     /locus_tag="JAM15_07145"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:490..492,aa:Phe,seq:gaa)
     gene            539..612
                     /locus_tag="JAM15_07150"
     tRNA            539..612
                     /locus_tag="JAM15_07150"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:573..575,aa:Met,seq:cat)
     gene            627..703
                     /locus_tag="JAM15_07155"
     tRNA            627..703
                     /locus_tag="JAM15_07155"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:661..663,aa:Ile,seq:cat)
     gene            721..797
                     /locus_tag="JAM15_07160"
     tRNA            721..797
                     /locus_tag="JAM15_07160"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:755..757,aa:His,seq:gtg)
     gene            806..881
                     /locus_tag="JAM15_07165"
     tRNA            806..881
                     /locus_tag="JAM15_07165"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:839..841,aa:Lys,seq:ttt)
     gene            889..962
                     /locus_tag="JAM15_07170"
     tRNA            889..962
                     /locus_tag="JAM15_07170"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:921..923,aa:Cys,seq:gca)
     gene            970..1046
                     /locus_tag="JAM15_07175"
     tRNA            970..1046
                     /locus_tag="JAM15_07175"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1004..1006,aa:Arg,seq:acg)
     gene            1059..1134
                     /locus_tag="JAM15_07180"
     tRNA            1059..1134
                     /locus_tag="JAM15_07180"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1092..1094,aa:Val,seq:tac)
     gene            1210..1623
                     /locus_tag="JAM15_07185"
     CDS             1210..1623
                     /locus_tag="JAM15_07185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798031.1"
                     /translation="MYIVIGNEIVDSEELKIIIDKNSEFKVEKDLSKSTKREDVIAYQ
                     LSIDLNYLDSLINEQCNLASLSDEEKFDEYMTLSDELALDLEELMPKYTIINARAYKL
                     DEVDGIVKIILAVAYADLGHLKLSDVVKRLSRQVD"
     gene            1932..5363
                     /locus_tag="JAM15_07190"
     CDS             1932..5363
                     /locus_tag="JAM15_07190"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002845968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HAT6798032.1"
                     /translation="MLKKFNKILVANRGEIAIRIFRACSELGIKSVGIYSKEDKYGLF
                     RTKADESYLIGEGKGPIDAYLDMDGIIDLAKRKKVDAIHPGYGFLAENAEFARKCEEN
                     GITFIGPSSKVMNMMGDKINSKKIAKEVNVQTIPGVEKAIRSTEEAKEVANKIGYPVM
                     IKASNGGGGRGMRIVHREEDLELEYETACSESRKAFGEDIIFIEKYIADPKHIEVQIL
                     GDNYGNIVHLYERDCSVQRRHQKIIEYAPAFSLDDKVRKEICEDAVKLSKHVGYSNAG
                     TLEFLVDANGGHYFIEMNTRVQVEHTVTEMVTGIDIVQSQILIAQGYSLDSEEINIKS
                     QDDVEIRGYSIQCRITTEDPKNKFMPDTGKIQVYRTGSGFGIRLDGGNGFTGANISPH
                     YDSLLVKTISWDRTFQGAINKTIRSIKELRVRGVKTNVGFLVNVLNNPIFSNGKCSTK
                     FIDENPDLFEITESKDRGTKLLQFIGDVIVNDNACKEKPLFDALHDPRMDKDGSKSEG
                     SKILFDKLGKSAYIEKIKNDKKLLLTDTTMRDAHQSLLATRIRTYDLLKAAKPTEKYQ
                     KDLFSLEMWGGATYDVAYRFLKESPWRRLQKLREEIPSIMFQMLLRASNGVGYKNYPD
                     NVIEEFTKESARQGIDVFRIFDSLNWVENMKPSINTALETGKIVEATMCYTGDILDKT
                     KTKYNLEYYIKMAQELESLGADIIAIKDMSGLLKPYSAYTLVKELKKNVKAPIHLHTH
                     DTSGNGVATCLMASEAGVDIIDAALESMAGLTSQPSLNAIVEALKNTERDTGIDLFGY
                     DELGKYYKDLRKVYNKFESDLTNSCAEIYNFEIPGGQYTNLKPQADSLGLVNRFDEVK
                     EKYKEANEVVGDIIKVTPSSKVVGDLAIFMTKNKLDKDNIIEEGKNLSFPDSVVDYCK
                     GMIGQPEGGIPKDLQEVVLKGEEAITVRPGSLLPAEDFDEIAKYLNEKYDINANIRNV
                     ISYALYPKVYEDYIKHLQHYNDISKLESDVFFYGLNKNEECEVEIEEGKVLTIRLVEI
                     GEVKENGFRTIGFELNGMVREVEIKDKNFSGKINNVEKADMNDPLQIGASIPGKVIKI
                     MVKEEDEVKANQPLIVIEAMKMETIIVAKTDGVIKSIKVKEDDMVEDKQLLMIMK"
     gene            5605..7533
                     /locus_tag="JAM15_07195"
     CDS             5605..7533
                     /locus_tag="JAM15_07195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HAT6798033.1"
                     /translation="MKVYDSKMLRNVAVLGHSGCGKTNLIETIAYTANTNKIPKLTDK
                     VNMTYSMGLIPIEYNDYKFNLLDTPGYFDFSGDVVSSLRASDAAIIVIDATAPIQVGT
                     EKSLELTESIPKIMFINKIDNEKARYKDAIAMLREKYNNKIVPMISPIYKDKNFVKLH
                     NVFENIDDLEGEFKEQAMSVKEALMELIAETDDQILDKYFNGEELTTEEIQKGIIIGI
                     QRGDIIPVICGSTINNIGTKEILDTISSYLEPIFTEESKPFRGLVFKTMVDPFVGKMS
                     YIKITEGVLSKDKDVFNINKNVKEKIANIYTLRNSELVEIEKAKAGDIVVITKVNSLK
                     TGDTISADKDAEALEKIDFPKPQIYYAVTPKNKGDEEKVASVLNKLVEEDPTLHWYRN
                     TETKQALLGGQGELHIKTIKNKMKDKFGVDVELNDLKVPYRETIKGTADVQGKHKKQS
                     GGHGQYGDVKIRFERCESDFEFTEEIFGGSVPKQYIPAVEKGLKDSMQKGILAGYPVT
                     NIKATLYDGSYHDVDSSEMAFKMAASAAFKKGMEEAHPILLEPIMKLKITVPEEYMGD
                     VMGDINKRRGKIFGMEPDDKGKQIIFAEAPQAETFKYAIDLRAMTQGRGYFEMELERY
                     GEVPSQFAEKIIGLATAK"
     gene            7986..8450
                     /locus_tag="JAM15_07200"
     CDS             7986..8450
                     /locus_tag="JAM15_07200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HAT6798034.1"
                     /translation="MATMTDIIEKFIKDLMEEDNSIQIQRNELANLFSCAPSQINYVL
                     TTRFTIDRGYYIESKKGGGGYVQIEKIRKSKDGHIRELLNEKIGSQISYKKAKELLEG
                     LKESDLINERELKLILYAIDDKSLCMPIYELKEKVRSNILKNIIIGLFSIEE"
     gene            8457..8951
                     /locus_tag="JAM15_07205"
     CDS             8457..8951
                     /locus_tag="JAM15_07205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA methylase"
                     /protein_id="HAT6798035.1"
                     /translation="MLCQKCNKNKASVYYNKIVNGEKTEMYLCSECAKENTEMNFNLD
                     MPFSMMDIFSNLGFQPKKELEEKLVCPKCNTTYSEFKNNGRFGCSECYNAFSSQVNPM
                     LQNIHGHIEHTGKAPKKSFYKISVENEIKELKEDLDRAIKNEEYELAAQFRDKIKYLK
                     GSID"
     gene            8967..9992
                     /locus_tag="JAM15_07210"
     CDS             8967..9992
                     /locus_tag="JAM15_07210"
                     /EC_number="2.7.14.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein arginine kinase"
                     /protein_id="HAT6798036.1"
                     /translation="MKENIVMKSRVRLARNLNNYPFPNKLDKECAMEIIEKVKNAFIN
                     SNLEQKEEFDFYKIEDLDQSKKMLMVEEHIISPDLAENDKSAVIVKKDKTISIMINEE
                     DHIRIQTICDDLNLEYAYSVANEIDDLLESSLEYAFNTKLGYLTSCPTNTGTGMRASV
                     MMHLPALSQLGYMDELYKISSQIGIAIRGIYGERTEALGNIYQISNQLTLGRTESNII
                     ENVSGLTKDAISKEIKAREILQKKLGIKLEDKIFRSIGTLENSRVMSSAEAMSHLSNI
                     KMGIEMNYIDKLDLRAIEQLMIGIQPAHQSIMYKSDDVENRDINRATYIRETLEKLRG
                     GMNCELQ"
     gene            9979..12426
                     /locus_tag="JAM15_07215"
     CDS             9979..12426
                     /locus_tag="JAM15_07215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HAT6798037.1"
                     /translation="MNFNRFTQRAKKAIDLAFESAKSLGHNIVGSEHILLGLLREEEG
                     IAAKVLSKVGFTEAYLEGKIVDMEGKGEEISEDIVLSPRSKQILELSGMFANKLKTNY
                     IGTEHILLAIIQEGEGIANKILNYAGVNDRTLAQLTIDMMGISDKNQYKAENSYTGNQ
                     NQAESKVLDKYGRNLTLYAKQNKIDPVIGREKEIQRVIQILSRRTKNNPVLIGDPGVG
                     KTAIAEGLATNIALGNVPETLKNKTLYSLEMGSLLAGAKYRGEFEERIKEVVDEVVKN
                     GNIILFIDEMHTIIGAGSTGEGSIDASNILKPALARGEIQVIGATTIDEYRKHVEKDS
                     ALERRFQPVMVDEPTKEDSIKILEGLRDKYEAHHKVKITDDAIKAAVELSTRYISDRY
                     LPDKAIDLIDEAASKVRLKENTPPSEIKKLELEIENIDKEKEEAVRCQDFEKAAKIRD
                     EQGLLKKQLEDVRERWNKSSKHSDLVDGEVIAEVVGLWTGIPVNKILEEEADRLLRLE
                     EILHNRVIGQEQAVKSISKAIRRSRAGLKDPNRPIGSFLFLGPTGVGKTELSKALAEV
                     QFGDENQIIRIDMSEYMEKHAVSRMIGSPPGYVGHDEGGQLTEKVRRNPYSVILFDEI
                     EKAHPDVFNILLQILDDGRLTDSKGRTVDFKNTIVIMTSNVGASTIGRQKTLGFSIAK
                     GDEEEKSQYEKMKENIMGELKQRFRPEFLNRIDDIIVFHSLNENHISKIVLLMAAKLQ
                     ERLKEMDIKLEMSDEAVKLISKSGFDLEYGARPLKRALQKELEDELSEAILKGNVKKG
                     SNVVAKVKDEKIVFETK"
     gene            12606..13979
                     /gene="radA"
                     /locus_tag="JAM15_07220"
     CDS             12606..13979
                     /gene="radA"
                     /locus_tag="JAM15_07220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HAT6798038.1"
                     /translation="MAKIKTKYVCQSCGYETAKWLGKCPECTKWNTFVEEIDQKSTKK
                     EVFIIDKSSSKPVSINSIESKEEERFTTDINELDRVLGGGIVKGSLVLVGGDPGIGKS
                     TLLIQVSSNVANLGKTVLYITGEESESQIKMRAKRLGINSENLYIFAENNLSIIESYL
                     ESVNPELIILDSIQTVFSPEISSAPGTVSQIKEGTSKFMKISKKMGISTFIVGHVTKE
                     GSLAGPKLLEHMVDTVLYFEGERYNTYRLVRAVKNRFGSTNELGVFEMRDLGLVELDN
                     PSKILISEKPKDVAGSVIISTVEGTRPMLLELQALVSPTSFGIPKRTSTGVDYNRVGM
                     LLAVLEKRVGLQIQNQDVYINIVGGIKINEPSIDLGIAISVASSFRNIPIDEDIAVTG
                     EVGLTGEVRAVSFIEKRIAECKKLGFKKIVVPRSNYDVVKETKGIEIWPVDNLRQAIN
                     IVLGRNQ"
     gene            13982..15052
                     /gene="disA"
                     /locus_tag="JAM15_07225"
     CDS             13982..15052
                     /gene="disA"
                     /locus_tag="JAM15_07225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA integrity scanning protein DisA"
                     /protein_id="HAT6798039.1"
                     /translation="MENFLDNKNMLYALKMISPGTPLRLGLNNVLRAKTGGLIVIATN
                     EDVMKIVDGGFAINAEYSPSYLYELAKMDGAIVLSGDVKKILFANAQLIPDYFIETSE
                     TGTRHRTAERVAKQTGAIVIGISQRRNVITVYRGNEKYVVEDISKIFTKANQAIQTLE
                     KYKTVLDQAVTNLNALEFNDLVTIYDVALVMQKMEMVMRVTSIIEKYVIELGDEGTLV
                     SMQLEELMGTTRIDQKLIFKDYNKENTEIKELMKKVKNLNSEELIELVNMAKLLGYSG
                     FSESMDMPIKTRGYRILSKIHRLPTAIIENLVNYFENFQQILDASIEELDEVEGIGEI
                     RATYIKNGLIKMKQLVLLDRHI"
     gene            15141..16235
                     /locus_tag="JAM15_07230"
     CDS             15141..16235
                     /locus_tag="JAM15_07230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HAT6798040.1"
                     /translation="MIRKVTRILFILLGFTIGITTYLTLMKDFEILTFGKETYGYIAA
                     VVAGIIIAILGYLIEPWVVNKVKEIAKIVDKELSKYPQTDILLGSMGLIVGFVIAYLL
                     SGLVNRIPIVGGILSLLLYLFLGYLGMKVALKSKNDLFNIGKLGRLANPIKDKDKDKE
                     NKKEVKAIPPKVLDTSVIIDGRIADICKTGFIEGKLIIPAFVLEELRHIADSSDDLKR
                     VRGRRGLDILNIIQKELNIEVEISERDFDDIAEVDSKLLKLAQVLNGKVVTNDYNLNK
                     VAQFQGVEVLNINELANAIKPVAIPGEDMVVQVVKEGKEAQQGVAYLDDGTMIVVDGG
                     RKYMNETIKVLVTSVLQTPAGRMIFAKPKN"
     gene            16364..18541
                     /locus_tag="JAM15_07235"
     CDS             16364..18541
                     /locus_tag="JAM15_07235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798041.1"
                     /translation="MRKKIISFLATFIIILTSASQYSFADDISTRGKVIFIDMNRTSM
                     SNMLRIKSLREELDNRGYIGLMNIRGDKGSDDRRSYASMGAGGRANVANEEDINFESS
                     SKDRNIVFESATGKSAKGINNLTINKSINENLNFGEYGSVLGSLGQSLSENGLKASVL
                     GNSDIIENGQLIKNRNLCLTAMDEYGRIPNGNVDTINKKDLSMPYGISTDYDKLIVET
                     KEAYKNNDVVFVELGDTYRLDLYKPNLNEKTYESMKDNIEKNIDVYLKNIFSMVGEND
                     TVYIASAFPSDLDYKNKRRLSPIIKLNGEGKGILSSSTTRREGIVTNLDVGVEILDNF
                     NIKNQNMVGRKYELINRDDNKEFLKDEYQKIVSISSIRSTILNGFVSIVFLSWIVAMI
                     AILFRKHISKNYKETTFFILKELLKIGIVMPLSFMITPIMNFKTPLAISLGIIIITLT
                     IYLISKVLIKNDLKNMLFFTGLTIVIMVIDAGFGSYLMKSNVMSYDCIIGARYYGVGN
                     EYQGVAIGSAIFTFAILLTYKNIPKWSIIVFSLVILITSASPIMGANVGSAISECVAF
                     LLFILLIYNVKIDFKKIVLLGIAVLFVLGVFVAIDMILGSNSHLGMFVKEIYTNGPGE
                     IIQTFSRKIEMNLKLAQTSAWVNILLTGIGVILVLMINQIRYFKQLIDEYPIVFKGFI
                     ASIAGCVVTLLVNDSGIVSSATAFIYVIVAMIILSINLVALKE"
     gene            complement(18685..19816)
                     /locus_tag="JAM15_07240"
                     /pseudo
     CDS             complement(18685..19816)
                     /locus_tag="JAM15_07240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904744.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
     gene            19801..21185
                     /locus_tag="JAM15_07245"
                     /pseudo
     CDS             19801..21185
                     /locus_tag="JAM15_07245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421229.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            21585..22538
                     /locus_tag="JAM15_07250"
     CDS             21585..22538
                     /locus_tag="JAM15_07250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HAT6798042.1"
                     /translation="MKKIGDLRLMMKCCSLYYEDNLNQQEIANQLGISRPTISRILKE
                     AFEQGIVKIQIVDVLKNDYQKIERSLERKYKLKEVIVVDDKQDALTQKQELARAVSEY
                     LTRVVKENDIIGVSIGTTLKEIPRYVEKSNCKNVTFIPLLGGIGDNEIDIHANQIAVS
                     LARAFGGDFKLLHAPAVMSDLSTKEKLCKDEKIKEVLDLIDKTTIAIVGIGNPMSLNS
                     TIMASGYMNEADIEDLKKYNSIGAICLQAFDKEGKTSILEFNQRVLGVKLEDLKKIKR
                     TIGVASGDEKIEAIKASLKAKFINSLAINHSLALKLLEDCD"
     gene            22576..23538
                     /locus_tag="JAM15_07255"
     CDS             22576..23538
                     /locus_tag="JAM15_07255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HAT6798043.1"
                     /translation="MSISKETLLEMYKRMNQARKFEEKVSWFFARGMVHGTTHLSVGQ
                     EASSVAAVMALEKGDLVSLTHRGHSQFIGMGIDLNKMMAELMGKETGFCKGKGGSMHI
                     ADIESGNLGANGVVGGGLTIAPGAALTQQYKKTGKIVLCSFGDGASNEGTFHEGINLS
                     SIWKLPIIFYCENNLYGMSTSIKRHMNIESIATRAASYGIEGISIDGYNPIEVYETVQ
                     KAAEKCRRGEGPVLIESRTYRWLGHSKSDANVYRTKEEIELWKAKDPIEFLKNYLIEN
                     NLSNEDELDKIQEFAKQSIEDAVEFAQNSPNPRIESLLEDVYAD"
     gene            23563..24549
                     /locus_tag="JAM15_07260"
     CDS             23563..24549
                     /locus_tag="JAM15_07260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HAT6798044.1"
                     /translation="MSTRELTYAQAIKEAMSEEMRRDENVIFMGEDIGIYGGAFGVSV
                     GMIDEFGPERVRDTPISEAAIAGAAAGAAATGLRPIMEVMFMDFVTISMDAIVNQAAK
                     MRYMFGGKAQVPMVVRCPGGSGTGSAEQHSQSLEAWFCHVPGVKVVAPSTPADAKGLL
                     KAAIRDNNPVIFVENKLLYRKKGFVPEDDYVIEIGKADIKREGTDVTVITYGRMLQSV
                     EEAAETLSKENINVEIIDLRTLYPLDKETIVKSVCKTGRVLICHEAAKTGGLGGEISA
                     LITESESFDYLDAPVKRICGKDVPIPYNPELEKAVVPRVDEIEEAIKSLIVR"
     gene            24562..25608
                     /locus_tag="JAM15_07265"
     CDS             24562..25608
                     /locus_tag="JAM15_07265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetoin dehydrogenase"
                     /protein_id="HAT6798045.1"
                     /translation="MVANKIKATPAARSQARKDNIKLDRLIGSGENGRIHLVDVLNYL
                     KDNKANTTPLARRIAEDLNIDLETIVGTGYSGKIRKCDVEKLTAKETIVSNNTSKYSE
                     KKELKIENENSSMFNTVEGIFEKPNPMRATVAKRMSESYFSAPVFTFNIEVDATELKV
                     LRAKLIDTVKESTGVKLTMTDLIVMAVSKILPNHQALNSAWTDEGIFRYKDVNIAIAV
                     GLDEGLYVPVVKNANKKSLKEIAKESKELAEKVKTGKLMPADQEGNTFTISNVGMYGI
                     TTFTPIINMPSSAILGVGATQDKFVPVNGEAKIKPIMNLSLTSDHRVIDGTVAAKFLK
                     DLKELLENPLSMLV"
     gene            25775..27505
                     /gene="lpdA"
                     /locus_tag="JAM15_07270"
     CDS             25775..27505
                     /gene="lpdA"
                     /locus_tag="JAM15_07270"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HAT6798046.1"
                     /translation="MSVEVIMPKAGVAMEEGTIVSWLKQEGEEVKIGEPILEITTDKV
                     NMEIESEGEGTLAVIIHKEEGEVLPVFTVIGVISEKGENQEEVKAKYLSGNVSKEDIV
                     EENQNIEVKEEKINKKECNHDYDVVVIGGGPGGYLSALKAALLGGRVALVEENILGGT
                     CLNRGCIPTKTYIKTAEILEEIDQLSKRGVKVTVDKEQDIKKAIKYKNRVVKKLTAGV
                     GGLLKSRDVDVFNLKASVKEEHKVILSDGKVLDTENIIIATGSKVRILPIKGIESNLI
                     ITSTEALDLETVPEELVIIGGGVIGCEFAEIFNSRGSKVTIVEMEDRVIPRMDKELSE
                     SLKYSLSKKGINVLTKKKVSEFKEEGNNILVCIEGEVPIKADLCLYAIGREANLSGIE
                     DLDIKIDKGSIVVNSKMETSIPSIYAVGDVTGGVMLAHAAFKMGEVAASNALGVNKEV
                     DLGALPSCVYTIPEVASVGITEEDARKKYNVKVGKFNFAGNGRALASGQEQGYVKVVA
                     DAKYGEILGIHMFGCGVAELINHAASFKALEIPTDEASELIFGHPCTSEALMEALADV
                     NGECLHLPKK"
     gene            27923..30871
                     /locus_tag="JAM15_07275"
     CDS             27923..30871
                     /locus_tag="JAM15_07275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAT6798047.1"
                     /translation="MRQRIKNLIENEDKKNPLTDEAISSRLNIRREDVTFLRNELKIE
                     DSRQRRKVVLIKAIKDILKEEKTINKNDITRRLNSIGFTVSRFTVIQYLKEIQDSGDL
                     KLDKESDDKKEEIINNRENKDIAFDKLIGSSGSLSTIIKLAKAAILYPPHGLHTIIMG
                     PTGVGKSELAECMYKFAVESSRFPKNAPFIVFNAADYSENPQLLLSQLFGHVKGAFTG
                     ADENKEGLVSKADGGILFIDEIHRLPHEGQEILFQLIDKGMVRKLGETRLTHKIDVMI
                     ISATSEPIDSHLLNTFKRRIPVTIEIPELVARPLNERFDIINNFFLIEAQRMGANIHI
                     KSDVLKALMLYDCIGNVGQLRSDIQVACARGLLNQLTNKLKEVNISISDVPGYVKQGL
                     IKIRNCRGKIENYVDGDLIIDSNLQGEIEKKNEDIYTFPDEIYKLTERRHIDLLEQGL
                     DFDVINRIIGGELESCIQKYIKQVKKVSISNNLPDISPIVGKYIVELTYEVIKIASQY
                     LSSLEPNLHLCLAVHLKAAFERLKEGKVISNAHLKEIIGNYPLEYSVAEKVAQYLKER
                     YNINLPKEEIGIIAIYFKMSSRRDMSEQKKIGVLLMAHGRVASSVCEVTNKLLGINHA
                     RYLDMPFEKKPEEMIEEATTIIKDIDEGRGVIILVDMGSLSYFGDIISGKTGINIRTI
                     SRFDTLLSIEVIRRAVLPDLTIDEIVDEVKGIEPQVKEKVSKCNNTKVDFRKPIILTL
                     CITGLGGACKIKKILEENIKSITEKVDIEPIGMIEYPSLDLEIKQISNDKNVIAIVGT
                     IDPQIANIPFFSLVDINDKAKLNQINNLIDTNQIGETNKKYELSDLIHKEDIFVDLQV
                     KSKEEVLKYMSKKLREKGYVTKNFYKKVVERDNLFPTELSDEIAIPHTDGIDVIRPAI
                     SIAILKKPIVWSKSKVKIILLLAVDQKCFNPLSTLLSFIETDEFKKIKNIKDRDFIRE
                     MILDGVNENN"
     gene            30849..31313
                     /locus_tag="JAM15_07280"
     CDS             30849..31313
                     /locus_tag="JAM15_07280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAT6798048.1"
                     /translation="MESMKIISSNLIFKNIEVSNNEDALKFLGQRLFDEQYVKESYIQ
                     AVVAREKKYATGLPTEIYGVAIPHTDIVHVNEPGIAIGILNKPVKFIMMGTDDTEIDV
                     KVVFMLAVKEPQEQLQLLEKLMTIFQDKNILNNIVDLSEESVSDLLNSKLKN"
     gene            31426..31728
                     /locus_tag="JAM15_07285"
     CDS             31426..31728
                     /locus_tag="JAM15_07285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAT6798049.1"
                     /translation="MGVTNVTKKILVACGTGVCTSTIAINKLKKALQDIGKLDMVNIT
                     QCKVVEVASKAPDYDLIICTTQVSSSIKTPVINGLPFLTGVGMDKLINDVLEELEL"
     gene            31790..33154
                     /locus_tag="JAM15_07290"
     CDS             31790..33154
                     /locus_tag="JAM15_07290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425524.1"
                     /note="with GatAB forms a phosphoenolpyruvate-dependent
                     sugar phosphotransferase transporter for galactitol;
                     subunit IIC forms the translocation channel and contains
                     the substrate binding site; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HAT6798050.1"
                     /translation="MEGLYMEILNFIVGLGAQVMMPIIICIFGLILGTKLGKSLRAGL
                     TVGVGFIGLNTIIALLTDNLGPATQQMVKNLGLSLSIIDVGWPAASAIAFASTVGALI
                     IPIGLVVNIVMLITNTTQTVDVDIWDYWHFAFTGALVAGATQSVMWGVFAAVANMVIV
                     LVMADLTAPGIEEYLGMPGISLPHGFTQAFVPIAIVVNKLLDLIPGINKIEINADTLQ
                     KKFGLFGEPLIMGSVIGVIIGIAAKYDIKGILQLGVTMGAVLILIPKMAALLMEGLLP
                     VSEAAQEFIEKRFKNRGKIYIGLDSAVGIGHPVTLSVALVLVPLTILIAAILPGNKVL
                     PFADLAVIPFALVLIVPITKGNVFRTLIIGIIIITSGLLIATNLAPLFTQMALNASFK
                     MPEGATMISSICDGANPLSWVFVKVMNYKVIGGVVFGVIALGMAIYNRNRIINENKKL
                     SIEE"
     gene            33189..33662
                     /locus_tag="JAM15_07295"
     CDS             33189..33662
                     /locus_tag="JAM15_07295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798051.1"
                     /translation="MKKYKYDSKRYLLSVTIPGFFMILILIYALFNNYTNFNLNIYSL
                     LIIVCTYGIFNTFISSSNPKKIIIDSKCIHFTSFMTTHKYEIKDIEKIRIREFYNKKI
                     YLKINDGKLFKGRYWIRTNMFNNSIALYSYFIELEECLYPDSLKFRNKKFENKNI"
     gene            33834..34484
                     /locus_tag="JAM15_07300"
     CDS             33834..34484
                     /locus_tag="JAM15_07300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798052.1"
                     /translation="MLLEKLRKEVLQASLDLLNYNLVTLTGGNVSGRDEQTGYIAITP
                     SGMDYRNLTPSDIVIVDVDGNIIDGKWKASVDLSDHLYIYKHREDINSIIHTHSTYSS
                     CFAILNEPIECASTTLANEVGGSVPVAKFSPPTSKKMGKCVIEAIGDKRACLLANHGV
                     IAVGPSVGHALTAAVMLEDSAKVYYLAKSIGTPVLLPDEEIQRARDVFFNVYGQDK"
     gene            34658..35590
                     /locus_tag="JAM15_07305"
     CDS             34658..35590
                     /locus_tag="JAM15_07305"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HAT6798053.1"
                     /translation="MYYLLNKSTNPYFNLALEEYLFLNDKYNDDIIIIWRNEDSIFIG
                     KNQNPYQEVHHDVIEKGEIPILRRISGGGTVYHDLGNINMSFIQKDRQLHEIDFLEHT
                     KFMQKMLSTLGLDVSITERKDLFLNGKKISGSAQSIKRKNSLYHGTLLYDSDLNKLTK
                     YLNSNKATESNATKSVSSKVTNIKFLLEKDINYFLDYCVEYLKSNIKNIKELELDEED
                     IKSVYNIGEDKYRKIEWTYGKTPKFQVVLPFNNESKINIHVNRWKVSKFFISYDDNVI
                     NMDKLLDLNFFKEEIKESILENYPHYIDLINLIF"
     gene            35864..36577
                     /gene="ispD"
                     /locus_tag="JAM15_07310"
     CDS             35864..36577
                     /gene="ispD"
                     /locus_tag="JAM15_07310"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HAT6798054.1"
                     /translation="MYSVIIVAAGSGRRMNLDINKQFIKLREKEIIAHTIQVFYENIN
                     IDEIVVCIKKEEEDFFKENIINKYNFKNIKIAYGGKERQDSIYNGLKKLDENCDIVLI
                     HDGARPFVDHRIINESIKVAKEKKAVVVGVPVSDTIKIVSDGTVQETPERNLLWAAQT
                     PQTFEYNLIIDAYEQAYKNNYYGTDDSMLVENIGQSVTMVMGSYENIKITSPEDLNIA
                     EQILNMEKRDEVNSRRRII"
     gene            36574..37059
                     /locus_tag="JAM15_07315"
     CDS             36574..37059
                     /locus_tag="JAM15_07315"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HAT6798055.1"
                     /translation="MRIGLGYDVHKLTENRKLIIGGVEIPHDKGLLGHSDADVLIHAI
                     MDSILGALALGDIGKHFPDTDEEYKGADSMKLLEHVYNLITSKGYKIGNIDSTIIAQS
                     PKMAPYIESMRSNISKVLNTDIDNINIKATTEEGLGFTGAKQGIASQSICLLLLTSQN
                     N"
     misc_binding    37154..37362
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            37426..39141
                     /locus_tag="JAM15_07320"
     CDS             37426..39141
                     /locus_tag="JAM15_07320"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HAT6798056.1"
                     /translation="MKMSKMFMPTLKEIPADAEITSHQLMVRSGMIKKMTSGVYNQLP
                     MGLRVFKKIEQIIREELNKKDCQEILCAALLPSELWKESGRWTAMGEEMFRLKDRTER
                     EYCLGPTHEEAFTDIIRQEITSYKQLPLNLYQIQVKYRDERRPRFGVMRTKTFTMKDA
                     YSFDVDDKGLDKSYQDMFDAYVSIFDRCGLENSPVQADSGAIGGSTSAEFMVKSEVGE
                     DEVVFCSGCDYAANVERAESCNLASQKEEMKELEEVHTPGAATIKELEEFLKTSPDKF
                     AKTLVYEADGKTVVVVVRGDREVNEIKVSNAIGSVIEFALATDDVVRKVTNAEVGFAG
                     PIGINADYVFIDKEIVEQRNIVVGANKTEYHIKNANYGRDFEGIVGDFRNVQEGDQCI
                     VCGKPLEIARGVEVGHIFKLGTKYSESMNANFIDKDGKSKPIVMGCYGIGVERTAAAI
                     IEQHNDEKGIIWPLSVAPYHVVIVPANMKNEEQISIAENIYNDLQAMGVEVLLDDRDE
                     RIGVKFNDSELIGIPMRITVGKNINEGKVEFKLRHKEDKEIIDIEEINEKVKAEFIRN
                     NVRLG"
     gene            39263..40708
                     /locus_tag="JAM15_07325"
     CDS             39263..40708
                     /locus_tag="JAM15_07325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002844244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Proline--tRNA ligase 2"
                     /protein_id="HAT6798057.1"
                     /translation="MAKNEKQFVEEITKMEDDFPQWYTDVITKTDLVDYAPVKGFMVV
                     KPYGYALWEKMQEFMDKKFKETGHKNCYFPLLIPESLLNKEAEHVEGFAPEVAWVTHG
                     GNKKLEERLCVRPTSETIICTMYAKWLKSYRELPYLYNQWCSVVRWEKSTRPFLRTSE
                     FLWQEGHTLHETAEEAQEETIQQLEVYKALCEELLAMPVVAGQKSESEKFAGGERTYT
                     IEAMMHDGKALQSGTSHFLGQHFTKAFDITFADREGNLANPYHTSWGASTRLIGGLIM
                     THSDNRGLVLPPRVAPIQVVIVPIAAKKGNVMETVDKIYADLKAKGVAVEVDDRDNYT
                     TGWKFNEWEMKGVPVRVEIGPKDIENNQAMVFRRDTLEKDSMPLEGLADAICDLFDVI
                     HNDMFEKARKHREDNTSIVENMDEFRKALEEKPGFIKTMWCGDAECEAKIKEETGATI
                     RCLPFEQENLGHKCVYCGKEADSMVVMAKAY"
     gene            41148..42629
                     /locus_tag="JAM15_07330"
     CDS             41148..42629
                     /locus_tag="JAM15_07330"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HAT6798058.1"
                     /translation="MNVRVRFAPSPTGFVHIGSLRTALYNYLFAKKMGGEYILRVEDT
                     DQSRLVEGAIENMLNAMKWAGVNHSEGVILDDSGKVVQKGEYGPYIQSQRLDIYQEYI
                     KQLLDSGKAYYCFCTKERLDEVRDAQRAAGETAKYDGHCKNLSKEEVEANIKAGIPYV
                     IRLRLPENHTIKFTDLVRGDMEFNTNDLDDQVLMKTDGFPTYHFAVVVDDYLMKITHV
                     IRGEEWVSSTPKHVYLYEAFGWEAPVFVHLPNILNKEKKKLSKRQGDVAVEDFKKKGY
                     LPEGLVNYVALVGWSPEDNQELFTMEELEKAFSVERVSKSGGVFDTEKLNWVNQHYIK
                     DGDDAYLTDLAIPFLIEDGFITEEEATNKYDFLKSMISVLKEKLQYVKEVTEHASIFF
                     GDKIEVETEEGREFLRLEHIPTLIDALREKIEKTEVLNAEFVQAMLKEIQKEYKIKGK
                     NLFMGSRIILTGQMHGPDLPKVMEVLGKETCLNRIAYVKNNIL"
     gene            43150..44547
                     /locus_tag="JAM15_07335"
     CDS             43150..44547
                     /locus_tag="JAM15_07335"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HAT6798059.1"
                     /translation="MKVYNTLTRTKEEFVPLEEGKVKMYVCGPTVYNYIHIGNARPFI
                     IFDTLRRYLEYRGYDVTYVQNFTDVDDKIINRSHEEGISPEEVAAKYIKEYFVDCDGL
                     GIKRATVHPQVTDNIQQIIEFIKELEDKGYAYAVNGDVYFDTNKFEGYGKLSGQKQED
                     LEAGARIEVNDQKRHPMDFVLWKAKKEGEPGWDSPWGEGRPGWHIECSVMSKRYLGET
                     IDIHAGGQDLTFPHHENEIAQSEARSGKTFSKYWMHNGYININDEKMSKSKGNFFTVR
                     DISKLYDLEIVRFFMLSAHYRNPVNFSDEMLNQAKAGLERLYNTKEKLEFTLSNLVES
                     PLTEKEVELVKELDDFRQKFIDAMDDDVNTADAVSVIFELAKLINSNVDENSSLEFAK
                     KCLDEFNELTGVLNIVNKKKDTVLDKDIEELIQKRTDAKKNKEFQLADDIRQQLLDMG
                     IVLEDTRQGVKWKRI"
     gene            44532..44945
                     /locus_tag="JAM15_07340"
     CDS             44532..44945
                     /locus_tag="JAM15_07340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HAT6798060.1"
                     /translation="MEKDIKMEKTELVTMSPLVLAYLGDTVYETYIREYLIRQNTQRK
                     VNDLHKLAIKYVKAKAQATIIHEIEIELTEEESKIYKRGRNQKSNTSPKNADIIDYKH
                     ATGFEALVGYLYLNNEIERLQYIINKGIKIIERDM"
     gene            45051..45809
                     /locus_tag="JAM15_07345"
     CDS             45051..45809
                     /locus_tag="JAM15_07345"
                     /EC_number="2.1.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010244513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent thymidylate synthase"
                     /protein_id="HAT6798061.1"
                     /translation="MKVKLISHTPEPEKVIAMAAKLCYSPVGTDEIEKDLTDESIEKF
                     LNMLLSIGHGSILEHASFTFSIEGISRACSHQIVRHRIASFSQQSQRYVKLEQFEYII
                     PPEIEKIEKAKELFIDSMKKDQENYDKLVEILFENHYNDLIKNGKNEKTAKRQAEKKA
                     IEDARYIFPNACETKMVFTINARSLFNFFEHRCCERAQWEIRNLAVEMLREVKRVAPI
                     LFKKTGPSCVNGSCPEGTMTCGDIVQVREKFKAL"
     gene            45822..46559
                     /gene="rlmB"
                     /locus_tag="JAM15_07350"
     CDS             45822..46559
                     /gene="rlmB"
                     /locus_tag="JAM15_07350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HAT6798062.1"
                     /translation="MASIEGRNPVIEAIKSDREIDKILIANSSKEGSIKKIIGMAKDK
                     NIIIQYVDKHKLDEVSTSHSHQGVIAYASEYKYYELDELIDLAKNKDEDPFFIILDEI
                     TDPHNLGSIIRTADAVGAHGVIIPKRRSVHITPVVAKASAGAVEYMPVCKVTNIVNTI
                     KRFKEEGLWIAAADMDGETFYKQNLTGPLGVVIGSEGFGISRLVKQNCDFIVKMPMIG
                     NVTSLNASVAGGILLYEIFRQRLDKSK"
     gene            46562..47089
                     /locus_tag="JAM15_07355"
     CDS             46562..47089
                     /locus_tag="JAM15_07355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HAT6798063.1"
                     /translation="MKKNINHYLIIDGYNIINAWDNLKELAKEDLEDSREKLIDDIIE
                     FSEFMGYKTIIVFDAYNVKNSREKVEKRKHITIVYTREHQTADSYIEKFITSLSKYDD
                     VKVATNDYAEQQMILGKGATRMSARELKLELDRSKNKMKEKNIGLRKKIQRNWLEERL
                     DKETLSKLENIRRKR"
     gene            47154..47801
                     /gene="sigH"
                     /locus_tag="JAM15_07360"
     CDS             47154..47801
                     /gene="sigH"
                     /locus_tag="JAM15_07360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigH"
                     /protein_id="HAT6798064.1"
                     /translation="MLVAKEKSYELVDNCQQDEYNIVLRASEGDKIALEYIITKYRNF
                     VKAKAKSYFLIGADKEDIIQEGMIGLYKAVRDFDGSKTNSFKCFAEICITRQIITAIK
                     TATRQKHIPLNSYVSLNKPIYDEESDRTLLDIIATSIVTDPEELIISKEELKNIESKM
                     NELLSDLELEVLELYLNGKSYQFIADKLKRDVKSIDNALQRVKRKLEKHLENRND"
     gene            47875..>49048
                     /gene="tuf"
                     /locus_tag="JAM15_07365"
     CDS             47875..>49048
                     /gene="tuf"
                     /locus_tag="JAM15_07365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007788515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HAT6798065.1"
                     /translation="MAKAKYERTKPHVNIGTIGHVDHGKTTLTAAITKTLYDRYQLGE
                     AVDFANIDKAPEERERGITISTAHVEYETPNRHYAHVDCPGHADYVKNMITGAAQMDG
                     AILVCSATDGPMPQTREHILLSRQVGVPYIVVFLNKCDMVDDEELLELVEMEVRDLLT
                     EYDFPGDDTPIVRGSALMALEDPKSEWGDKIVELFEQIDEYIPAPERDTDKPFLMPVE
                     DVFSITGRGTVATGRVERGVLKVQDEVELVGLTEAPRKVVVTGVEMFRKLLDQAQAGD
                     NIGALLRGVQRNEIERGQVLAKTGSVKAHTKFTAEVYVLKKEEGGRHTPFFDGYRPQF
                     YFRTTDVTGACKLPEGIEMVMPGDNVTMEVDLINSIVVEEGLRFSIREGGRTVASGV"
BASE COUNT        20080 a         5301 c         9327 g        14340 t
ORIGIN      
        1 tttaatttaa taaacgagcg ggaatagttc agtggtagag cgcaaccttg ccaaggttga
       61 agtcgcgagt tcgaatctcg tttcccgctc caaattttat gtttatgttg taatgtgggt
      121 gcatagctca gctggataga gcaacgccct tctaaggcgt gtgtccgggg ttcgaatccc
      181 tgtgcgctca ccacatatat attggggatt agccaagtcg gtaaggcaca tgactttgac
      241 tcatgtatgc gtaggttcga gtcctgcatc cccagccaaa cagtatggtc tattagctca
      301 gtcggtagag cacctgactt ttaatcaggg tgtcccgcgt tcgagtcgcg gatagatcac
      361 caatggagag gtgtccgagt ggtttaagga gctggtcttg aaaaccagtg acttcgaaag
      421 gggccgtggg ttcgaatccc accctctccg ccaaatgccc agatagctca gtcggtagag
      481 caggggactg aaaatccccg tgtcggtggt tcgattccgc ctctgggcac caaaatgtgg
      541 cggtatagct tagttggcta gagcgttcgg ttcatacccg aaaggtcata ggttcgactc
      601 ctattaccgc tactaaaatt taatgtgggc cattagctca gttggttaga gcgcccggct
      661 cataaccggt aggtctgggg ttcgagtccc tgatggccca ccacattaaa ttaacttatg
      721 gtgggtatag ctcagttggt tagagcgcca gattgtggct ctggaggtcg tgagttcgac
      781 tctcattatc caccccaact tatatggtct attagctcag tcggtagagc acctgacttt
      841 taatcagggt gtcccgcgtt cgagtcgcgg atagatcacc aaaaaggcgg cgacatagcc
      901 aagtggtaag gcagtggact gcaactcctt gatccccagt tcgaatctgg gtgtcgcctc
      961 caataaaatg cgctcatagc tcaactggat agagtgtctg actacgaatc agaaggttag
     1021 gggttcgagt ccctttgggc gcaccatatg aatagcgagg gattatagct cagctgggag
     1081 agcacctgcc ttacaagcag ggggtcacag gttcgagccc tgttaatccc accagtgcaa
     1141 acctctagta aaattactag aggttttatt tttgattgaa aaagttttta tatttaggag
     1201 gtaaaaaatt tgtatatagt aataggaaat gaaatagttg atagtgaaga acttaaaata
     1261 attatagata aaaatagtga atttaaagtt gaaaaagatt taagtaaaag cacaaaaaga
     1321 gaagatgtaa tagcatatca gttaagtata gatttaaatt acctagattc tcttataaat
     1381 gagcaatgta atttagccag tctatctgat gaagagaaat ttgatgaata tatgactttg
     1441 tctgatgaac ttgcactaga tttagaagag ttaatgccaa aatatacaat aataaatgct
     1501 agagcatata aattagacga ggtagatgga attgtaaaaa taatactagc tgtagcgtat
     1561 gcagatttag ggcacttaaa actttctgat gtagtaaaga ggctatctag acaagtagat
     1621 taggatatga atatgaacta tattaaaaaa atgtataaaa tcttacgtaa agatgaaaat
     1681 aattatgtaa acatagaaaa aaacagtata aaatcaagtc aattgtagaa attttcacat
     1741 aaattcatct gaaattctat aaaaaatgcc ttaattttaa tgaggtaaat cgagtttaca
     1801 cagtctaaaa attacttata tttataaatt tatcttatta attaaggaac tttcttaaac
     1861 atcttcaaaa ataaagtatt ttagtctata atctttaata ttacacaaac aataaaggag
     1921 aagaatagag tatgcttaaa aagtttaata aaatactagt ggctaataga ggcgaaatag
     1981 ctataagaat atttagagcc tgttcagaat tggggataaa aagtgttggt atatacagta
     2041 aggaagataa gtatggattg tttagaacaa aagcggatga atcatatttg ataggagaag
     2101 gtaaagggcc aatagatgca tatttagata tggatggaat aatagaccta gcaaagagaa
     2161 aaaaagttga tgctatacat ccaggatatg gttttctagc ggagaatgca gaatttgctc
     2221 gtaaatgtga agagaatgga attactttta taggaccatc atctaaggta atgaatatga
     2281 tgggggataa gattaactct aaaaaaatcg caaaagaagt taatgttcaa actataccag
     2341 gagtagaaaa agcaataaga agtactgaag aagcaaagga agttgcaaac aaaataggat
     2401 atcctgttat gataaaagca tctaatggcg gtggcggtag aggtatgaga attgtacatc
     2461 gcgaagaaga cttagagctt gaatatgaaa ctgcttgtag tgaatcaaga aaagcttttg
     2521 gagaagatat tatatttata gaaaaatata tagctgatcc aaaacatata gaagttcaaa
     2581 tattaggtga taattatgga aatatagttc acttatatga aagagattgt tcagttcaaa
     2641 gaagacatca aaaaataata gaatatgcac cagctttttc gttagatgat aaagtaagaa
     2701 aagagatatg tgaagatgca gttaagttat caaaacatgt gggttattct aatgcgggaa
     2761 cattagaatt tttagtagat gcaaatggtg ggcattattt tatagagatg aacacaagag
     2821 tacaggttga acatactgta acagagatgg ttacaggaat agatatagtt caaagtcaaa
     2881 tactaatagc ccaaggttac agcttagata gtgaagaaat taatataaaa tcacaagatg
     2941 atgtggaaat aagaggttac tctatccaat gtagaataac tacagaagac cctaagaata
     3001 aattcatgcc tgatacaggt aaaattcaag tttatagaac tggttcagga tttggtataa
     3061 gactagatgg aggaaatgga tttacagggg caaacataag tcctcattat gatagtttat
     3121 tggttaaaac aatatcttgg gatagaacat tccaaggagc aataaataaa actataagat
     3181 ctataaaaga acttagagtt agaggtgtta aaactaatgt aggattccta gttaatgttt
     3241 taaataatcc tatattctca aatggtaaat gtagtactaa gtttatagat gaaaatccag
     3301 atttatttga aataacagaa agtaaagaca gaggaacaaa attacttcaa tttataggag
     3361 atgtaattgt aaatgataat gcttgtaaag aaaaaccatt atttgatgca ttacatgacc
     3421 caagaatgga taaggatggt tcaaaatcag aaggaagtaa aatacttttc gataagttag
     3481 gtaaatctgc atatatagaa aagataaaaa atgataagaa attactatta acagatacaa
     3541 caatgagaga tgcacatcaa tcattattag caacaagaat aagaacatat gacttattaa
     3601 aagctgctaa gccaacagaa aaatatcaaa aggatttatt ctcacttgaa atgtggggag
     3661 gagctactta tgatgttgca tatagatttt taaaagaatc tccttggcgt agattacaaa
     3721 agctaagaga agaaatacca agcataatgt tccaaatgtt gcttagagca tcaaatggag
     3781 ttggatataa aaactatcca gataatgtaa tagaagaatt tacaaaagaa tctgctagac
     3841 aaggtataga tgtatttaga atatttgatt cattaaactg ggttgaaaat atgaaaccat
     3901 ctattaatac agctttagaa actggaaaaa ttgttgaagc aactatgtgt tatacaggtg
     3961 atatactaga taagactaaa actaaataca atctagaata ttatataaaa atggcacaag
     4021 aattagaaag cttgggagca gacataatag caataaaaga tatgtcaggt cttcttaaac
     4081 catattcagc ttacacacta gttaaagagt taaagaaaaa tgtaaaagca ccaatacatt
     4141 tacacactca tgatacaagt ggaaatggtg tagcaacttg tttaatggcg tcagaagctg
     4201 gagtagacat aattgatgct gcattagaat ctatggcagg acttacaagt cagccatcac
     4261 ttaatgctat agtagaggca cttaagaata cagagagaga tacaggaata gatttatttg
     4321 gatatgatga gttaggaaaa tattataagg atttaagaaa agtttataat aaatttgaaa
     4381 gtgatttaac taattcttgt gcagaaatat ataattttga aataccagga ggccaatata
     4441 caaacttaaa acctcaagct gatagtttag gattagttaa tagatttgat gaagttaaag
     4501 aaaaatataa agaagctaat gaagttgtag gagatataat aaaagtaact ccatcttcaa
     4561 aagttgtagg agacttagct atctttatga ctaaaaataa attagataaa gacaatataa
     4621 tagaagaagg taaaaattta tcattcccag attctgttgt ggattactgt aaaggtatga
     4681 ttggtcaacc agaaggtgga ataccaaaag atttacaaga ggtagttcta aaaggtgaag
     4741 aagctataac agtaagacca ggttcattat taccagcaga agattttgat gaaatagcta
     4801 aatatctaaa tgaaaagtat gatataaatg ctaatataag aaatgttata agttatgctt
     4861 tatatccaaa agtatatgaa gattatatca aacatctaca acattataat gatatatcta
     4921 aacttgaaag tgatgtattc ttctatggat taaataaaaa tgaagaatgt gaagtagaaa
     4981 tagaagaagg taaggtatta acaataagat tagttgaaat tggtgaagtt aaggaaaatg
     5041 gatttagaac tataggattt gagttaaatg gaatggttag agaagtagaa ataaaagata
     5101 agaatttctc tggaaaaatt aataatgttg aaaaagctga tatgaatgac cctcttcaaa
     5161 ttggagcaag cataccagga aaagttataa aaataatggt taaagaagaa gatgaagtaa
     5221 aagcaaatca accattaatc gttatagagg ctatgaagat ggaaactata atagttgcta
     5281 agactgatgg agtaattaag tcaatcaaag taaaagaaga tgatatggtt gaagataaac
     5341 aattattaat gataatgaag taatttaatt aaaataaatt aaaaagcact ctgaaatgtt
     5401 taataaaaaa tgttttagag tgtttttatt tattttaatt aaatatttgt taaaaaaaag
     5461 aggacaatta cctccagatg tagaaataaa gctagtaagg aaaatgttat ctaaaaattc
     5521 taaatatagt aaatattttc cataatattt cttaggaaat aacagcaaag ataaaataca
     5581 taaatttaaa aggtgggtgc ttatatgaag gtttatgata gtaaaatgtt gagaaatgta
     5641 gcggtattag gacatagcgg atgtggaaaa acaaatctaa tcgaaactat agcttacaca
     5701 gcaaacacta ataagatacc taaattaaca gacaaggtaa atatgactta tagcatggga
     5761 ttaataccta tagagtataa tgattataag tttaacttat tggatacccc aggatatttt
     5821 gactttagcg gagacgttgt gtcatctctt agagcaagtg atgcagcaat aatagtaata
     5881 gatgcaacag cgcctattca agttggtaca gagaaatcat tagaactaac tgagagtatt
     5941 cctaagataa tgtttataaa taaaatagat aatgaaaagg caagatacaa agatgcaata
     6001 gcaatgttaa gagaaaaata caataataag atagttccta tgataagtcc tatatacaaa
     6061 gataaaaact ttgtaaagtt acataatgtt tttgaaaaca tagatgattt agaaggtgaa
     6121 tttaaggaac aagctatgag tgttaaagaa gcattaatgg aacttatagc agaaactgat
     6181 gaccaaatat tagataaata ttttaatgga gaagaactaa ctacagaaga gatacagaaa
     6241 ggtattatta taggtataca aagaggtgat attatacctg taatatgtgg ttcaactata
     6301 aataatatag gcacaaagga aatattagat acaatatcaa gttatttaga acctatcttt
     6361 acagaggaaa gcaaaccatt taggggatta gtatttaaaa ctatggttga cccatttgtt
     6421 ggaaagatgt catatataaa aattactgag ggtgtacttt ctaaggataa agatgttttt
     6481 aatataaata aaaatgtaaa agaaaaaata gctaatatat atacattgag aaatagtgaa
     6541 ttagtagaaa tagaaaaagc taaagctggt gatatagtag ttataactaa agttaattct
     6601 ctaaaaacag gagacactat atctgcagat aaagatgcag aagctttaga aaagatagat
     6661 tttcctaaac cacaaatata ttatgcagta actcctaaga ataaaggtga tgaagaaaaa
     6721 gtagcatctg tattaaataa actagtagaa gaggacccta cattacattg gtatagaaat
     6781 acagagacaa aacaagcact tttaggaggt caaggagagc ttcatataaa aacaattaaa
     6841 aataaaatga aagataagtt tggtgttgat gttgaattga atgaccttaa agttccttat
     6901 agagaaacta taaaaggaac agctgatgta caaggaaaac ataaaaagca atcaggtggt
     6961 catggtcaat atggagacgt aaaaataaga tttgaaagat gtgaatctga ttttgaattt
     7021 acagaagaaa tatttggtgg ttctgtacca aaacaatata taccagcagt tgaaaaaggt
     7081 ttaaaagact ctatgcaaaa aggtatatta gcaggatatc ctgttacaaa cataaaagct
     7141 acgctttatg atggttcata ccatgatgta gactcttctg aaatggcctt taagatggca
     7201 gcaagtgcag cctttaaaaa aggtatggaa gaagcacacc caatactact agaacctata
     7261 atgaaactta agataactgt tccagaagaa tatatgggag atgtcatggg tgatataaat
     7321 aagagaagag gaaaaatatt tggaatggaa ccagatgaca aagggaaaca aataatattt
     7381 gcagaagctc cacaagcaga gacatttaaa tatgcaatag atttaagagc aatgacacaa
     7441 ggtagaggat actttgaaat ggaattagag agatatggag aggttccatc acagtttgca
     7501 gaaaaaataa ttgggttagc tactgcaaag taatgaacaa aataaataga aaaataatta
     7561 atatatatta ttaaaaatat ttttagggtt ttaactaggt ataggtttat gttaggtaaa
     7621 cttataccta gtttttatac atttttgatg aataaaaaaa tatataatac tttcttaaat
     7681 attttaataa aaagaaagta tttttttatt attattttta caaatgttta gtaataaaga
     7741 tgagaaggta tatttaaaat ataaagtatt taaagttctg aaatctaatc atgaagcaaa
     7801 aaattagcat ttggttatca ataaatataa taaataaaaa ctcataatta atgaaagaat
     7861 aaattcatgt ctaaatttct ataaaaaatt taaatttata caatttaggg ctttaaaaat
     7921 ttaaataata ggtgtaaaat aatagtcaaa gaaagtcaaa aataaaaagg tgtgtggtga
     7981 tattaatggc aactatgaca gatataattg aaaaatttat taaagatttg atggaagaag
     8041 ataatagcat acaaattcaa agaaatgaac tagcaaactt gtttagttgt gcaccatcac
     8101 aaataaatta tgtcttaaca acaagattta caatagatag aggatattac attgaaagta
     8161 aaaaaggtgg cggaggatat gttcaaatag aaaaaatacg aaaaagtaaa gatgggcata
     8221 ttagagaact actaaatgaa aaaataggaa gtcagatatc ctataaaaaa gcaaaggaat
     8281 tattagaagg tttaaaagag tcggatttga ttaacgaaag agaattaaaa ttaatattat
     8341 atgcaataga tgataaatca ttgtgtatgc caatatatga attaaaagag aaggtaaggt
     8401 ctaatatttt aaagaatata ataataggat tatttagtat agaggagtga taatttatgc
     8461 tatgtcaaaa atgcaataag aataaagcat ctgtatatta taataagata gtcaatggag
     8521 aaaaaacaga gatgtattta tgtagtgagt gtgcaaaaga gaatacagaa atgaatttta
     8581 acttagatat gcctttttca atgatggata tattttctaa tttaggtttt caacctaaaa
     8641 aagaacttga ggaaaagcta gtttgtccta aatgcaatac aacatatagt gagtttaaga
     8701 ataatgggag atttggatgt agtgaatgtt ataatgcatt tagtagtcaa gtaaatccaa
     8761 tgcttcaaaa tatacatggg catatagaac atacaggaaa agcacctaaa aaatcttttt
     8821 ataagataag tgtagaaaat gagattaaag aactaaaaga agatttagat agagctataa
     8881 aaaatgaaga gtatgaatta gcagctcaat ttagagataa aattaaatat ttaaaaggtt
     8941 ctattgacta agattggagt gatattatga aagagaacat agtcatgaaa tcaagagtta
     9001 ggctagctag aaatttaaat aactatccat ttccaaataa attagataaa gaatgtgcca
     9061 tggaaataat agaaaaagta aaaaatgcgt ttattaattc taacttagaa caaaaagaag
     9121 aatttgattt ctataaaatt gaagatttag accaatctaa aaaaatgctt atggttgaag
     9181 aacatataat aagcccagat ttagcagaaa atgataaaag tgcagttata gtaaaaaaag
     9241 ataaaactat aagcataatg ataaatgaag aagaccatat aaggatacaa actatatgtg
     9301 atgatttaaa cttagaatat gcatatagtg tagcaaatga aatagatgat ttgttagaat
     9361 caagtttaga atatgccttt aacacaaagc taggttatct aacatcttgt ccaactaata
     9421 caggaacagg aatgagagct tctgtaatga tgcatttacc agcattaagt caactaggct
     9481 atatggatga actttataaa atttcatcac aaataggtat agcaattaga gggatatatg
     9541 gagaacgaac agaagcattg ggaaatatat atcaaatatc taatcaactt acacttggaa
     9601 gaacagagtc taatattata gaaaatgtaa gtggacttac aaaagatgca atttcaaaag
     9661 aaataaaagc tagagaaata ttgcaaaaaa aattaggtat aaaactagaa gataaaatat
     9721 ttagatcgat agggacactt gaaaattcaa gagtaatgag tagcgcagag gcaatgagcc
     9781 atctatcaaa tataaaaatg ggaatagaaa tgaactatat agataaacta gatttaaggg
     9841 ctatagaaca acttatgata ggtatacaac cagcgcatca gtcaataatg tataagagtg
     9901 atgatgttga gaatagagat ataaatagag caacatatat tagagaaact ttggaaaaat
     9961 taagaggagg gatgaattgt gaacttcaat agatttacac aaagagctaa aaaggcaatt
    10021 gatttagcgt ttgaatctgc taaaagtcta ggacacaata ttgtcggaag tgaacatata
    10081 cttttaggtc ttttaagaga agaagaaggt atagctgcta aagttctaag taaagttgga
    10141 tttacagaag cttatttaga aggcaaaata gttgatatgg aaggtaaggg agaagaaatc
    10201 tcagaagata tagtattaag tccaaggagt aaacaaatac ttgaattatc aggaatgttt
    10261 gcaaataaat taaaaacaaa ttatattggg actgagcata tattattagc aattattcaa
    10321 gaaggtgaag gaatagctaa taagatttta aattatgctg gagtaaatga taggacttta
    10381 gcccaattaa caattgatat gatgggtatt agtgataaaa atcaatacaa agcagagaat
    10441 agttacacgg gcaaccagaa tcaagcagaa tctaaagtac ttgataagta tggaagaaat
    10501 cttacactat atgcaaaaca gaataaaata gaccctgtaa taggtagaga aaaagaaata
    10561 caaagagtaa tacaaatatt aagtagaaga actaaaaaca atccagtgtt gataggagac
    10621 ccaggtgtag ggaaaacagc catagctgaa ggtctggcta caaatatagc cttaggaaat
    10681 gttccagaaa cactaaaaaa caaaacttta tactctttag agatgggttc attattggct
    10741 ggagctaagt atagaggaga atttgaagaa agaattaaag aagttgtaga tgaagttgtt
    10801 aaaaatggaa acataatctt atttatagat gagatgcaca caataatagg ggctgggtct
    10861 actggagaag gctctataga tgcttcaaat atattaaagc cagccttagc aagaggagaa
    10921 atacaagtta taggtgcaac tacaattgat gaatatagaa agcatgttga aaaagattct
    10981 gctctagaaa gaagattcca accagttatg gtagatgaac caactaaaga ggactcaata
    11041 aaaatattag aaggattaag agataaatat gaagctcatc ataaagttaa aataactgat
    11101 gatgctataa aggcagctgt agaattatca actagatata tatcagacag atatctgcca
    11161 gataaagcta tagacttgat tgatgaagct gcatcaaaag taagattaaa agaaaataca
    11221 cctccttcag aaataaaaaa attagaacta gaaatagaaa atatagataa agaaaaagaa
    11281 gaagcagtaa gatgtcaaga ctttgagaaa gcagccaaaa taagagatga acaaggtcta
    11341 cttaaaaaac aattagaaga tgttagagaa agatggaaca agtcatctaa acattcagat
    11401 ttagttgatg gagaagttat tgctgaagta gtgggcttat ggacaggaat accagttaat
    11461 aaaattcttg aagaagaggc tgatagactt ttgagacttg aggaaatact gcacaataga
    11521 gttataggtc aagaacaagc agtaaaatct atttcaaagg caatcagaag gtcaagagca
    11581 ggtcttaaag accctaatag accaattggt tcatttttat ttttaggtcc aacaggagta
    11641 ggtaaaacag aattatctaa ggcattagca gaagtgcaat ttggagatga aaatcaaata
    11701 attagaatag atatgtctga atatatggaa aaacatgctg tgtcaagaat gataggttca
    11761 cctccaggtt atgtaggtca tgatgaaggt ggtcaattaa ctgaaaaagt aagaagaaat
    11821 ccatattcag ttatcttatt tgatgagata gaaaaagctc atccagatgt atttaatatt
    11881 ctgttacaaa ttctagatga tggtagacta actgattcaa aaggaagaac tgtagatttt
    11941 aagaatacta ttgtaataat gacatcaaat gttggagcat ctacaattgg tagacaaaaa
    12001 actttaggat ttagtatagc taaaggagac gaagaagaaa aatctcaata tgaaaaaatg
    12061 aaagaaaata taatgggtga attaaaacaa agattcagac cagagttttt aaacagaata
    12121 gatgatataa ttgttttcca ctcactaaat gaaaatcata tatcaaaaat agtactttta
    12181 atggcagcga aactacaaga gagattaaaa gaaatggata taaaattaga aatgagtgat
    12241 gaggctgtta aattaatttc taaatctgga tttgacttag aatatggagc aagacctctt
    12301 aaaagagctt tacaaaaaga gttggaagat gagctatctg aagcaatctt aaaaggtaat
    12361 gtgaaaaagg gaagtaatgt agtagcaaaa gtcaaagatg aaaaaatagt ttttgaaact
    12421 aaataattta atagagttgc attttaaaat attgcaaata taagttttat aatctaaaca
    12481 aaattttaag ggcaatgaat ctataataat tcattgtcct taattatttt atttaatctt
    12541 tacatattgt ctttcagata tgctaaaatt atagtataga ataaaaaatt aaggatgata
    12601 aaagtatggc aaaaataaaa acaaaatatg tatgtcaatc ttgcggatat gaaacagcta
    12661 aatggcttgg taaatgtcca gaatgtacaa aatggaatac atttgtagaa gaaatagacc
    12721 aaaaaagcac caaaaaagag gtctttataa tagataaatc ttcatctaaa ccagtcagta
    12781 taaactcaat agaaagtaaa gaagaagagc ggtttacaac agatataaat gaattagata
    12841 gagtgcttgg aggaggtata gttaaaggct ctttagtgct tgttggtggt gaccctggta
    12901 taggtaaatc aacactttta atccaagtat ctagtaatgt tgccaattta ggaaaaactg
    12961 ttttatatat aactggagaa gaatcagaat ctcaaataaa aatgagagct aaaagattag
    13021 gtattaactc agaaaattta tatatatttg ctgaaaataa tttaagtata attgaatctt
    13081 atttagaaag tgtaaatcca gaattaataa ttctagactc aattcaaact gtcttcagtc
    13141 cagaaatatc ctcggcacca ggaactgtca gccaaattaa agaaggtact tcaaaattca
    13201 tgaaaatttc taaaaaaatg ggaatttcaa cgttcatagt tgggcatgtt acaaaagaag
    13261 gttcactagc aggaccaaaa ttattagagc atatggttga tactgttcta tattttgaag
    13321 gagaaagata taatacttat agattagtaa gagctgttaa aaatcgattt ggttcaacta
    13381 atgaacttgg agtgtttgaa atgagggatt taggattagt agaacttgat aatccatcta
    13441 aaattttaat ctctgaaaaa ccaaaagatg tagcaggttc agtaataata tctactgtag
    13501 aaggtacgag accaatgtta cttgaattgc aagcattagt ttctcctaca agttttggta
    13561 taccaaaaag aacatctaca ggagtcgatt acaatagagt aggtatgtta ttagcagtat
    13621 tagaaaaacg tgttggtttg caaatacaaa atcaagatgt ctatataaac atagttggag
    13681 gaataaagat aaatgaaccc tcaattgatt tagggatagc catttctgta gcatctagtt
    13741 ttagaaatat accgatagat gaagatatag ctgttacagg agaagtggga cttacaggag
    13801 aagttagagc agtaagcttt atagaaaaaa gaatagctga gtgtaaaaaa cttggattta
    13861 aaaagatagt agttcctaga agtaattatg atgttgtaaa agagaccaaa ggcatagaaa
    13921 tatggccagt agataactta agacaagcta taaatatagt acttgggagg aatcaataaa
    13981 tatggagaat tttctagata ataaaaatat gctatatgca ttaaaaatga tatctcctgg
    14041 aactccactt agattaggtc taaacaatgt actaagagct aagactggtg gattaattgt
    14101 aattgcaaca aacgaagatg taatgaaaat agtagatgga ggatttgcta taaatgcaga
    14161 atattcacca tcatatctat atgaattagc taaaatggat ggagctatag ttttaagtgg
    14221 tgatgtaaag aaaatattat ttgctaatgc acaacttata cctgactatt ttatagaaac
    14281 atcagagaca ggaacaagac atagaacagc agaaagagta gcaaaacaaa ctggtgctat
    14341 agtcatagga atttcacaaa gaagaaatgt tataacagtt tatagaggaa atgagaagta
    14401 tgtagtcgaa gatatatcta agatatttac taaggcaaat caggctatac aaactctgga
    14461 aaaatataag acagtattgg accaagctgt aacaaattta aatgccttag agtttaatga
    14521 tttggtaact atttatgatg ttgcattagt catgcaaaag atggaaatgg taatgagagt
    14581 tacaagtata attgaaaaat atgtgataga attgggtgat gaaggaactt tagtaagtat
    14641 gcaattagaa gaattaatgg gtacaaccag aatagaccag aaattaatat tcaaagatta
    14701 taataaagaa aacacagaaa taaaagaact tatgaaaaag gtcaaaaatt taaattcaga
    14761 agaactaata gaattggtta atatggcaaa actattaggg tatagtggtt tttcagaaag
    14821 tatggatatg cctataaaaa caagaggtta taggattctt agcaaaatac atagactacc
    14881 aacagcaata atagaaaact tagtaaatta ttttgaaaac tttcaacaaa ttttagatgc
    14941 atctattgaa gaattagatg aggttgaagg aataggtgaa ataagagcaa catatataaa
    15001 aaatggactc ataaaaatga aacaattagt cttattagat agacacatat gatgaatttt
    15061 aaatgaattt tactactttt ttcttgaata taatatacac tttggtctat aatagataag
    15121 tataactagg gggtgaagca ttgataagga aagtaacaag aatattgttt attttacttg
    15181 gatttacaat aggtataaca acctatttaa cattaatgaa agattttgaa atattaacat
    15241 ttggaaaaga aacatatggt tatatcgcag ctgtagtagc aggtataata atagccattt
    15301 taggatatct tatagaacca tgggttgtaa ataaagtaaa agaaattgct aaaatagtgg
    15361 ataaagaatt gtcaaaatat cctcagactg atatattgtt agggtctatg ggtcttatag
    15421 taggatttgt tattgcgtat ttattaagtg gattagtaaa tagaatacca atagtaggtg
    15481 gaatactatc cttactatta tatttattcc taggatatct tggaatgaaa gttgcgctta
    15541 aaagtaaaaa tgatttattt aatattggaa aactaggaag attagcaaat cctattaagg
    15601 ataaagataa ggataaagaa aataaaaaag aagtaaaagc cattcctcca aaagtattag
    15661 atacaagtgt aataattgat ggaagaatag ctgatatttg taagactggg tttatagaag
    15721 gaaaacttat tattcctgct tttgttttgg aggaactaag acatattgca gattcttcag
    15781 atgatttaaa aagagtaaga ggtagaagag gtctggatat attaaatata attcagaaag
    15841 aattaaatat agaagttgaa ataagtgaga gagactttga tgatatagca gaagttgata
    15901 gtaaattatt aaagcttgct caggttttaa atggaaaagt tgttacaaat gattataact
    15961 taaataaagt tgctcaattc caaggtgttg aagtattaaa tataaatgag ttagctaatg
    16021 ctataaaacc agttgctata ccaggtgaag atatggttgt tcaagtggtt aaagaaggaa
    16081 aagaggctca acaaggtgtt gcatatctag atgatggaac tatgatagtt gttgatggag
    16141 gaagaaaata tatgaatgag actataaaag tactcgttac ttctgttctt caaactcctg
    16201 caggtagaat gatatttgca aaacctaaaa attaatatgt tcaaagaaac ctataatttg
    16261 ggctgtttat tttaaataga tggtccaaat ttatttattt ataacgataa tgtttaatgt
    16321 attcttaaag atggggattt aaatcagaaa gcagggagaa tttatgagaa aaaagattat
    16381 atctttctta gcaacattta tcataatatt aacatcagca agtcagtata gttttgcaga
    16441 tgatatatca acacgtggaa aagtaatatt tatagatatg aatagaacta gtatgagtaa
    16501 tatgttaaga ataaaatcat taagagaaga actagacaat agagggtata ttggcttgat
    16561 gaatataaga ggcgataaag gaagtgatga tagaaggtca tatgctagta tgggtgctgg
    16621 tggtagagct aatgtggcta atgaagaaga tattaatttt gaaagctcga gtaaggatag
    16681 aaatatagtt tttgaatcag ctacaggaaa aagtgcaaaa ggtataaata atttaactat
    16741 aaataagtct ataaatgaaa atttaaactt tggagagtat ggttctgtat tagggtcatt
    16801 aggacaaagt ttatctgaga atggattaaa agcatctgta ttgggtaatt cagatataat
    16861 tgaaaatggt caacttataa aaaatagaaa tttatgtcta actgcaatgg atgaatatgg
    16921 aagaatacct aatggaaatg tagatactat aaataaaaaa gacttatcta tgccttatgg
    16981 aatatcaact gattatgata aattgattgt agagaccaaa gaagcttaca aaaataatga
    17041 tgtggttttt gtggagcttg gagacacata tagattagat ttatataaac caaatttaaa
    17101 tgaaaaaaca tatgagagta tgaaagataa catagaaaaa aatatagatg tatatttaaa
    17161 aaatatattt tctatggttg gagaaaatga cactgtctac atagcaagtg catttccaag
    17221 tgatttagat tataaaaata aaagaagact ttctccaata ataaaattaa atggagaagg
    17281 gaaaggtata ttatcatctt caactactag aagagaaggt attgtaacaa atttagatgt
    17341 tggggttgaa atattagaca actttaatat aaaaaatcaa aatatggttg gaagaaaata
    17401 tgaacttatt aacagagatg ataataaaga atttttgaag gatgaatatc aaaaaatagt
    17461 atctatttca agcataaggt ctacaatact gaatggtttt gtaagcatag ttttcttgtc
    17521 atggatagtt gctatgattg caattttatt tagaaagcat atatcaaaaa attataaaga
    17581 aacaacattt tttatattaa aggaactttt aaaaatagga atagtaatgc cattgtcatt
    17641 tatgataaca ccaataatga atttcaaaac accattagca atatctttag gaataattat
    17701 aataacactt actatatatc ttataagtaa agttttaata aagaacgatt taaaaaacat
    17761 gctgtttttt actggattaa ccatagtaat tatggttatt gatgctggat ttggctcata
    17821 tttaatgaaa agcaatgtta tgagttatga ctgtataatt ggagctagat attatggagt
    17881 gggaaatgag tatcaaggtg tggcaatcgg tagtgcaata tttacatttg caattttact
    17941 tacatataaa aatataccaa agtggtctat aatagttttt tctttggtta tcttaattac
    18001 aagtgcatct ccaattatgg gagcaaatgt tggaagtgct atttctgaat gtgttgcatt
    18061 tttactattt atactattaa tatataatgt gaagatagac ttcaaaaaaa ttgtattatt
    18121 aggtatagca gtattatttg tattaggagt ttttgtagca atagatatga ttttgggaag
    18181 taattcacat ttaggtatgt ttgtaaaaga aatttatact aatggaccag gagaaataat
    18241 acaaacattt agtagaaaga tagagatgaa cttgaagcta gctcaaacca gtgcatgggt
    18301 aaatatacta ctaactggaa tcggagtaat tttagttctt atgattaatc agattagata
    18361 ttttaaacaa ttaattgatg aatatccaat tgtatttaaa ggctttatag cgtcaatagc
    18421 aggatgcgtt gtaactcttt tagtaaatga ctctggaatt gtgtcatcag ctacagcttt
    18481 tatttatgta attgtggcta tgattatatt aagtataaat ctggtagcat taaaagaata
    18541 agttgcatat aggctatata taaatattga tatgttaatt taaatttatt ttgtaaaaat
    18601 aaatttaaag aagaaatttt ataaaaatta gttattatat aaaaatccca agtttatttt
    18661 aacttgggat ttttatataa taatttaaat tttatcttgt ttcaatataa tttgaaagga
    18721 tgtacttttc cctaaaatgc ttgaaagcga aatattccct ccatgtgcat caataatctg
    18781 cttaacaata aacaatccta atcctttgtt ttgtgtatta tgatttttgc tactataata
    18841 tttgtcaaaa atatcatctg ctttttccgc atttacccca acaccattgt cagtagtatt
    18901 aatgtaaatt tgttcagaac tctgttttaa gcaaatttct atttttgtac catcaggatt
    18961 atgttcaaca caattcatta aaaggttata aagagcctct atacattaat gtctcatcta
    19021 tggctaaata caaatattct aaatctgtat aaaatccaaa tatctgtttt ttagattttg
    19081 gattattagc tacatcagca ataaggtttt gaagaaatgc aaccatttca acctgtgtgt
    19141 gtttaagaag tatttttcca gacgaatcta taaaaaatgt cagacttaaa ttgtctatta
    19201 atttttcaat atatactcct tttttatata tgttatctaa aaatatcgtt ctctcttctt
    19261 cactaaaact gtggtttttg ttaagcgtta gagatgaata tcctgtgatg tatgataatg
    19321 gcgttttcaa atcatgtgat acaccagcaa gccaatcagt ttttgcaact tcaagttttt
    19381 ctcgttcaat ttcagtttct tgaagcttat tgcctaaaga ttttatattt acaatgactt
    19441 ctttatacat aaaatagtac cattttaatt tctcattatt ggtaaaggct tttttgacta
    19501 ttgcataatc tcctttagat aaattactta ttgaacaaat tatcaagtaa agtggtcgaa
    19561 caagaaataa gcaaaaaagt atccctcctg taataaagca gaaagaaatt ataagtatgc
    19621 ttgggaaata tccaatagat gaatcagcca catataaaaa ttcatgtgat ttttcaggat
    19681 atattaattg attaagtaat atgaataatg taacgaagta tactagaaat ataaagagac
    19741 ctgttgtaaa gtaagcaata aaacgaaagt ataatttcaa gggctttaat tgttggtgta
    19801 atgacaggat gtacatctca ggctacttca tcgaaaagtt caacgcctaa gtcaataact
    19861 aaaacaatag aaaaagttac tcgtgcaagt tgcgaaaaac aactaacaga aataaaagga
    19921 aagtatgaga aaaatccaaa tgacgaagtt ctaagattag aatatgctca aatactattt
    19981 aaattaggtg acattacaaa aacacaagtc ccttgatgaa tttgaagaag ccttctccag
    20041 atgtgattta tctttctgca cgaatagaat atctgaatgg taattatgag caggctgaaa
    20101 aactatataa tactcttata gagcaatatc ctgataaatt caaagcaaaa gctgaaaaag
    20161 gattgacact aacatattat caaacaaatc aatatcaaaa atctgaaaaa ttatccgaag
    20221 catcagaaga taaaaacaat agtataaata gtgtattgga aatgatgaaa gcttttaagg
    20281 ataaacaacc aaatcaaatt gactggaatg gaaaaagcga aacagtgatt ccttttatca
    20341 caaccgaacc tctgccagtt gtgccagtag agataaatgg aaaaaggata aatgctgtta
    20401 ttgatactgg tggcccaatg tttactattg atcagaaact tgcaaaagaa cttggtataa
    20461 aaacagcttc aaaaaacgaa aatgaatttg ctggaggtaa cactgttgaa actggttttg
    20521 gtcaagctga ttcacttact ataggagatg taaatattaa aaatgtacct gtaatgttgg
    20581 gaccatttga tgggtttgaa gaggggctta aggattatga tgttcatggt attattggta
    20641 caggtgtatt gaaggaattt atacctacga tggattatcc tagtggtaaa ttaatattaa
    20701 gacctcgaaa tgaagtcggt agagagaatc ttaataaaat gcttgcagat gataaaatat
    20761 tggaagaaat gccatttacg cttgcagcca ttcattttat gtatggaaaa ggatcagcca
    20821 atcagaaaag tggacttaac tacttcattg attcaggact tggtgacgaa aaaggtgttg
    20881 gaattatatt acctaaagaa acaatagatt ctttgaagat tcctatgcca gagctaaata
    20941 aagctcctga aggacaaggt ggaatgggag gaagtgatta taaggaaggc cattttgaca
    21001 tttcatcata tggactgggt aatttacaat taaaaaatgg tgtaggatat tattttacag
    21061 gtggagtttt ggattatgat gaggaagttg gatttgttag tgatggattg ataagtcatc
    21121 attattttaa taagtataaa tggtcaattg atttcgattc taggaagatg acatttagca
    21181 aatagaaata gcatataaca caaattgcgt gattaagttt cacttcttta aaggcatgga
    21241 ggtacgagga aagtatctcc gtgtttttta tatgtaaaaa tatttcataa gcaaaatgta
    21301 atagataact tgtttacaaa tatatcagga gtaatagtat tatagttcat ctaattacag
    21361 agatacattg gttagtcaag tttctagtag cgttataaca gaattagata gagtagaaaa
    21421 agctaaaatt atatttttac tagtatttat tgtaacaatt ttctcattat caaaaaaaac
    21481 agttgacttt ttatatgaac cccttctata atgttattga aattaagtaa aatgattgaa
    21541 caaatgtaaa gataattgaa aagcttgatt ttggaggaaa gcaaatgaaa aaaattggag
    21601 acttaagatt aatgatgaag tgttgttcac tttattacga agataatttg aatcaacagg
    21661 aaatagcaaa tcaattggga atatcaagac caacaatatc aagaatatta aaagaagctt
    21721 ttgaacaagg aatagtaaaa atacagatag ttgatgtttt gaaaaatgat taccaaaaaa
    21781 tagagagaag tttggagaga aaatataaat taaaagaagt aatagtagta gatgataaac
    21841 aggatgcact aacacaaaaa caagaactag caagagctgt atctgaatat ttaactagag
    21901 tagtaaagga aaatgatata ataggtgttt caataggaac aacactaaaa gaaataccaa
    21961 gatatgtgga aaaaagtaac tgtaaaaatg ttacatttat acctctatta ggagggattg
    22021 gagacaatga aatagatatt catgcaaatc aaatagcagt aagtttagcg agggcttttg
    22081 gaggtgattt taaattatta catgctccag ctgttatgtc tgacttgtct acaaaagaga
    22141 aactttgcaa agacgaaaaa attaaagaag tactagattt aatagataaa acaactatag
    22201 caattgtggg tataggaaat cctatgagtt taaactcaac aataatggct tctggataca
    22261 tgaatgaagc agatatagaa gatttaaaaa aatacaactc aataggtgcg atttgtttac
    22321 aagcctttga taaagaagga aaaacttcta tacttgaatt taatcaaaga gtattaggag
    22381 tgaaactgga agatttaaaa aagataaaaa gaacaatagg tgtcgcttca ggagatgaaa
    22441 aaatagaggc aataaaggca tcattaaaag cgaaatttat aaatagttta gcaattaatc
    22501 acagtttagc acttaaatta ttagaagatt gtgactaata gaaagataga taaaagttaa
    22561 caggagggaa tgtatatgtc aatatcaaaa gaaacattgc ttgaaatgta taagagaatg
    22621 aatcaggcta gaaaatttga agagaaagtt agctggtttt ttgcaagagg tatggttcat
    22681 ggaacaactc acttatctgt aggtcaagaa gcgtcaagtg tggcggctgt aatggcttta
    22741 gaaaaaggag atttagtatc attaactcat agaggacata gtcaatttat aggaatggga
    22801 atagacctaa ataaaatgat ggctgaactt atgggtaaag aaactggatt ttgtaaggga
    22861 aaaggaggct caatgcatat agcagatatt gagtcaggta acttaggagc aaatggagtt
    22921 gtaggtggag gtcttacaat agctccagga gctgcactta cacaacagta taaaaaaaca
    22981 ggcaaaatag ttttatgtag ttttggtgat ggagcatcaa atgaaggtac ttttcatgaa
    23041 ggaataaatt tatcttcaat atggaaattg ccaataatat tttactgtga gaataattta
    23101 tacggtatgt caacaagcat aaaacgtcat atgaatatag aaagtattgc cactagagca
    23161 gcttcttatg gaatagaagg aatatcaata gatggatata acccaataga agtatacgaa
    23221 acagtacaaa aagctgctga gaagtgtaga agaggagaag gacctgtatt aattgaaagt
    23281 agaacttata gatggttagg tcattcaaaa tcagatgcaa atgtatatag aacaaaagaa
    23341 gaaatagaat tatggaaagc aaaagaccct attgaatttt taaaaaatta tcttatagaa
    23401 aataatctat ctaatgaaga tgaattagat aagattcaag aatttgcaaa gcaatcaata
    23461 gaagatgcag tagagtttgc tcaaaatagc ccaaatccaa gaatagagtc tttattagag
    23521 gatgtatatg cagactaaga atggtaaagg aggaaaataa aaatgagtac aagggaatta
    23581 acatatgcac aagcaataaa ggaagcaatg tcagaagaaa tgagaagaga tgaaaatgta
    23641 atatttatgg gagaagatat aggaatatat ggaggagcat ttggtgtatc agttggtatg
    23701 atagatgaat ttggaccaga aagagtaagg gatactccta tatcagaagc agctatagca
    23761 ggagcggcag caggtgcagc agcaactggt ttaagaccta ttatggaagt aatgtttatg
    23821 gactttgtaa caatttctat ggatgcaatt gtaaatcaag cggcaaaaat gagatatatg
    23881 tttggaggaa aagcacaagt tccaatggtt gttagatgtc caggaggttc tggaactggt
    23941 tcagcagagc aacattcaca aagtttagaa gcttggtttt gtcatgtacc aggagtaaaa
    24001 gtagttgcac cttctacacc agcagatgct aagggattgt tgaaagcagc tataagagat
    24061 aataatccag tcatatttgt tgagaataaa ttgttataca gaaaaaaagg ttttgtgcca
    24121 gaagatgatt atgtaattga aattggaaag gcagatatta aaagagaggg tactgatgtt
    24181 acagtaatta cttatggaag aatgttacaa agtgttgaag aagcagcaga gactctatca
    24241 aaagaaaata taaatgttga aattatagat ttaagaactt tatatccatt agataaagag
    24301 actatagtaa agagtgtatg taaaactggg agagttttaa tttgccatga agcagctaag
    24361 actggtgggc taggtggaga aatatcagcc ctgataacag aaagtgaatc atttgattat
    24421 ttagatgctc cagtaaaaag aatttgtgga aaagatgtgc caataccata taatccagag
    24481 ttagaaaaag cagttgtccc aagagttgat gaaatagaag aagcaataaa atctttaatt
    24541 gttagataag gagggataga tatggtggca aataaaataa aagccacacc agcagctaga
    24601 agtcaggcaa gaaaagacaa tataaaatta gataggctga ttggaagtgg agaaaatgga
    24661 aggattcatt tagtagatgt gttaaattat ttaaaagata ataaagcaaa tactactcct
    24721 ttagctagaa gaatagcaga agatttaaat atagatttag aaactattgt aggtactgga
    24781 tatagtggaa agataagaaa gtgtgatgtg gaaaaattaa ctgcaaaaga aactattgta
    24841 tcaaataata catctaaata tagtgagaaa aaagagctga aaattgaaaa tgaaaattca
    24901 agcatgttta acacagtaga aggaatattt gaaaagccaa atccaatgag agctactgta
    24961 gcaaaacgaa tgtcagaaag ttattttagt gctcctgtat ttacattcaa tatagaagta
    25021 gatgctacag aattgaaggt acttagagca aagttaatcg acacagtaaa agaatcaact
    25081 ggagtaaaat taactatgac agatttaata gtaatggcag tatctaaaat acttccaaat
    25141 catcaagcct taaattcagc atggacagat gagggtatat ttagatataa agatgtaaat
    25201 atagctattg cagttggttt agatgaaggc ttatatgttc cggtagtaaa aaatgcaaac
    25261 aaaaagtctt taaaagaaat agcaaaagaa agcaaagaac ttgcggaaaa agtaaagaca
    25321 gggaaactta tgccagcaga ccaagaaggt aatacattta caataagtaa tgttggaatg
    25381 tatggtataa ctacatttac acctataata aatatgcctt caagtgcaat cttaggggta
    25441 ggtgctacac aagataagtt tgttccagta aatggagagg ctaaaataaa acctataatg
    25501 aacttatcat taacatcaga ccatagagta atagatggaa cagtagctgc aaaattctta
    25561 aaagatttaa aagaattgtt agaaaatcct ttatcaatgc ttgtataggt tttgatattt
    25621 cgttactgat ataaatagtt tgaatagatt atattattat aattgtttca gtaaatttaa
    25681 agcttttata tattaagaat tatttttaac agtaactata tgtgaatatg atttgcttaa
    25741 ttaaaatata tgaaaataaa taggaggaga gcctatgtca gtagaagtaa taatgccaaa
    25801 agcaggagta gccatggaag aaggtactat agtatcttgg ctaaagcaag aaggcgaaga
    25861 agtaaagatt ggagaaccta tactagaaat aacaacagat aaagttaata tggagataga
    25921 gtcagaagga gaaggtacac ttgctgtaat catacataaa gaggaaggtg aagtattacc
    25981 agtatttaca gtaataggtg taatatcaga aaaaggggaa aatcaagagg aagtaaaagc
    26041 taaatattta tctggaaatg tttcaaaaga agatatagtt gaagagaatc aaaatataga
    26101 agttaaagaa gaaaaaataa acaaaaaaga gtgtaatcat gattatgatg tagtggtaat
    26161 aggaggagga cctgggggat atttatcagc attaaaagca gctcttttag gtggaagagt
    26221 tgctttagtt gaagaaaata tactaggagg tacttgctta aatagaggtt gtatccctac
    26281 aaagacttat ataaaaacag cagaaatatt agaagaaatt gaccaattat caaagagagg
    26341 tgtaaaagta actgtagata aagaacagga tattaagaag gccataaaat ataaaaatag
    26401 agtagttaaa aaacttacag ctggtgttgg cggattatta aaaagtagag atgtagatgt
    26461 gtttaatctt aaagctagtg ttaaagaaga gcataaagta attttatcag atggaaaagt
    26521 tttagataca gaaaatataa taattgctac aggttccaaa gtaaggatat tacctataaa
    26581 aggaatagaa tcaaatttaa taataactag tacagaagca ttagatttgg aaacagtgcc
    26641 agaagaatta gtaataattg gtggtggagt gattggttgt gaatttgcag agatattcaa
    26701 ttcaagaggt tctaaagtaa ctatagtaga aatggaagat agagtaatcc caagaatgga
    26761 taaagagtta agcgaatctt taaaatattc tcttagtaaa aaaggtataa atgtattaac
    26821 taaaaagaaa gtttctgaat ttaaagaaga aggaaataac atattagtgt gcattgaagg
    26881 tgaagtgcca ataaaagcag atttatgtct atatgctata ggaagagaag ctaatctttc
    26941 tggcatagag gacttagata ttaaaataga taaaggttca atagttgtaa atagtaaaat
    27001 ggaaacaagt ataccaagca tatatgcagt aggtgatgtt actggaggtg taatgttagc
    27061 tcatgctgct tttaaaatgg gagaggtagc agcttcaaat gctctaggtg tgaataaaga
    27121 agttgactta ggtgcattac ctagttgtgt ttatacaatt ccagaagtag catcagttgg
    27181 tattacagaa gaggatgcta gaaaaaaata taatgtaaaa gttggtaagt ttaattttgc
    27241 tggaaatgga agagctttag cttctggtca agaacaagga tatgtgaaag tagtagcaga
    27301 tgctaaatat ggagaaattt taggtataca tatgtttgga tgtggtgtag cagaacttat
    27361 aaatcatgca gcatcattta aagcattaga gatacctact gatgaagcaa gtgagttgat
    27421 atttggtcat ccatgtactt cagaagcttt aatggaagct ttggcagatg taaatggaga
    27481 atgtttacac ttacctaaaa aataaatcta aacataaatt attaatttaa gtctattatt
    27541 aatattaatt tatatcataa aattttaaaa cacttactta gccatacccc ttattatgca
    27601 aataatttat ttgtataata aggggtattt tttatggaaa aatatagaat atagaatcct
    27661 tgtagttttt gttgtacaaa aaagatagta atataaaata acattatcat tttagaatga
    27721 tttcaattgt aattaggaaa agtgattttt ttgtttttaa aaaaagtatt atttgtaaaa
    27781 tataaaaaaa aatttcttaa tatttgaata aaagaatagc ttaatttaaa tgttattact
    27841 ttataaaaaa ataataagta caaaaaaaac aatatatggc atataagttg ctatataaat
    27901 aataaggagg gaacaattat aaatgaggca aagaataaaa aacttaattg aaaatgaaga
    27961 taagaaaaat cctttaacag atgaagcgat ttcaagtagg ttaaatattc gaagagaaga
    28021 tgttaccttt ttgagaaatg agttaaaaat agaagattca agacaaagaa gaaaagttgt
    28081 tttaattaaa gctataaaag atattttaaa agaagaaaaa actataaata aaaatgatat
    28141 aacaagaaga ttaaacagca ttgggtttac agtatcaaga tttacagtca tacaatactt
    28201 aaaagagatt caagattctg gtgacctaaa acttgataaa gagagtgatg ataaaaaaga
    28261 agaaataatc aataatagag aaaataaaga tatagcattt gataaactca taggtagtag
    28321 tggtagctta agtacaatta taaaactagc caaagcagca attctttatc cacctcatgg
    28381 tcttcatact attattatgg ggccaactgg tgttggaaag agtgagttag cagagtgtat
    28441 gtataaattt gcagtagaat catccagatt ccctaagaat gcaccattta tagtttttaa
    28501 tgcagcagat tattcagaga atccacagct tttgctatca cagttatttg gacacgttaa
    28561 aggtgctttt acaggagctg atgagaacaa agaaggatta gtatcaaagg cagatggagg
    28621 aatattgttt atagatgaaa tacatagatt acctcatgaa ggtcaagaaa tactatttca
    28681 actgattgat aaaggtatgg tcagaaagtt aggagaaaca agactaacac ataaaataga
    28741 tgtaatgatt atttcagcaa cttctgagcc aatagattct catttactta atacatttaa
    28801 aagacgtata cctgtaacaa ttgaaatacc agaattagtt gcaagaccat taaatgagag
    28861 gtttgacatt ataaataatt tcttcttaat agaagctcaa agaatgggag caaacataca
    28921 tataaagtca gatgtattaa aagctcttat gctttacgat tgtataggta atgtaggtca
    28981 acttagaagt gatattcaag tagcttgtgc taggggacta ttaaaccaac ttacaaacaa
    29041 actaaaagaa gtaaatataa gcatatcaga tgtacctgga tatgtaaaac aaggtcttat
    29101 aaaaatcaga aattgtagag gtaaaataga aaattatgta gatggggatt taattataga
    29161 ttcaaatctt caaggtgaga tagaaaagaa aaatgaagat atatatactt ttccagatga
    29221 aatatacaaa cttactgaaa gaagacatat tgatttattg gaacaaggtt tagattttga
    29281 tgttataaat agaatcattg gaggagaact agaaagttgc attcaaaaat acataaaaca
    29341 agttaaaaaa gtttctatta gtaacaatct tccagatata agtccaattg ttggaaaata
    29401 tatcgtagag ctaacttatg aagtaatcaa aatagcatca caatacctaa gttcactaga
    29461 accgaatcta catttatgtt tagcagttca cctaaaagca gcttttgaga gattaaaaga
    29521 aggaaaagta atatcaaatg ctcatttgaa agaaataata ggaaattatc cactagaata
    29581 ttctgtagca gaaaaggtag ctcaatattt aaaggaaaga tataatataa acttaccaaa
    29641 agaagaaata ggtataatag caatatattt taaaatgagt agtagaagag atatgtctga
    29701 acaaaaaaag ataggtgtac ttcttatggc tcacggaaga gtagcatctt ctgtatgtga
    29761 ggttacaaat aaactattag gaattaatca cgcaaggtat ttagatatgc catttgagaa
    29821 gaagccggaa gaaatgattg aagaagctac tacaataata aaagatattg atgaaggtag
    29881 aggtgtgatt atattagtag atatgggttc actttcatat tttggagata ttatttctgg
    29941 aaagactgga attaatataa ggacaatatc tagatttgat acattgcttt ctatagaggt
    30001 tatacgaaga gcagttttac cagatttaac aatagacgag atagttgatg aagttaaagg
    30061 tatagagcca caagtaaaag aaaaggttag taaatgtaac aatacaaaag tagattttag
    30121 aaaacctata attttaacat tatgtattac tggattaggg ggagcttgta agataaaaaa
    30181 aatcctagag gaaaatatta aaagtataac tgaaaaggtt gatatagaac ctataggtat
    30241 gattgaatat ccaagtcttg atttagagat aaaacaaata agcaatgata aaaatgtaat
    30301 cgccatagtt ggaacaattg accctcagat agcaaatatc ccttttttta gtctagtaga
    30361 cataaatgat aaagcaaagt taaatcaaat aaataaccta attgatacaa atcaaattgg
    30421 tgaaacaaat aaaaaatatg aattatcaga tttaatacat aaagaagata tatttgtgga
    30481 tttacaggtt aaatcaaaag aagaagttct aaaatatatg agtaaaaaac ttagagagaa
    30541 aggttatgtg acaaaaaatt tctataaaaa agtagtggaa agagataact tatttccaac
    30601 tgaattatca gatgaaatag caatacctca cacagatgga atagatgtaa ttaggccagc
    30661 tataagtata gccatcttaa agaagcctat tgtgtggagt aaaagtaaag taaaaataat
    30721 acttttatta gctgtagacc aaaagtgttt taatccatta agcactctac tctcatttat
    30781 agaaacagat gaatttaaga agataaaaaa cattaaagat agagatttta ttagggagat
    30841 gatattagat ggagtcaatg aaaataatta gtagcaattt aatttttaaa aatattgaag
    30901 tgtctaacaa tgaagatgca ttaaagtttt tgggacaacg tttgtttgac gaacagtatg
    30961 taaaagaaag ctacatacaa gctgttgtag caagagaaaa aaagtatgct acaggattac
    31021 caacagaaat atacggagtg gcaataccac atacagatat agtacatgta aatgagccag
    31081 gaatagcaat tggaatactg aataaacctg taaaatttat aatgatgggt acagacgata
    31141 ctgaaattga tgtaaaagtt gtatttatgt tagcagtgaa agagccacaa gaacaattgc
    31201 aactattaga aaaacttatg actatatttc aagataagaa tatactaaat aatattgttg
    31261 acttaagtga agaaagtgtg agtgatttat taaactctaa attgaaaaat taaacatgta
    31321 aagtatatta aaaatgtaaa attaaacatg caaagtatgt taaaaaatat aaaaagatta
    31381 ttaaagattt ctaactatag atatctttaa aataaaataa tttcaatggg ggtgactaat
    31441 gtgactaaaa agatattagt tgcatgtgga acaggagtat gtacttcaac aattgctata
    31501 aacaaattaa agaaagcact tcaagacatt ggtaaattgg atatggttaa tattacacaa
    31561 tgtaaagtag tagaagttgc atcaaaagca cctgattatg atttaataat ttgtactaca
    31621 caagtatcta gtagtataaa aacaccagtg ataaatggat tacctttttt aactggtgtc
    31681 ggaatggata aattaatcaa tgatgtatta gaagagttag aattataatt aaaaaaatta
    31741 aggaacatgg tctctaaaat cataagtttt agagacttaa aattaaataa tggagggtct
    31801 ttatatggag atattaaatt tcattgttgg tctaggtgca caagtaatga tgccaataat
    31861 aatatgtatt tttggtttga tattaggtac aaaactagga aaatctttaa gagctggttt
    31921 aactgtggga gttgggttta taggtcttaa cactattata gctttgctaa cagataattt
    31981 aggtccagct acacaacaaa tggttaagaa tttagggcta agtttatcaa taatagatgt
    32041 aggatggcca gcagcatcag ctatagcttt tgcatcaaca gtaggggctt taattattcc
    32101 aataggtctt gtggtaaata tagttatgct aattactaat actactcaaa ctgttgatgt
    32161 agacatatgg gattactggc attttgcttt tacaggagct ttagtggcag gggctactca
    32221 aagtgtaatg tggggagtat ttgcagcagt agcaaatatg gtaattgtat tggtaatggc
    32281 agatttaact gctccaggta tagaggaata tttaggtatg ccaggtatat ctcttcctca
    32341 tggatttaca caggcatttg ttccaattgc tatagtagta aataaattat tagacctaat
    32401 accaggtata aataagattg agataaatgc tgatacattg cagaaaaaat ttggattatt
    32461 tggagaacct ttaataatgg ggtctgtaat aggtgtaata attggtattg ctgcgaaata
    32521 tgatataaaa ggaatattac aattaggtgt aactatggga gctgtattaa tattaattcc
    32581 aaagatggca gcattattaa tggaaggatt attaccagta tcagaagctg cacaggaatt
    32641 tattgagaag agatttaaaa acagaggcaa gatttatata ggcttagatt cagcagtagg
    32701 aataggtcat cctgttacat tatcagttgc actagtgttg gttcctttga ctatacttat
    32761 agcagctata ttgccaggaa ataaagtttt accatttgca gatttagcag taattccatt
    32821 tgcacttgta ttaatcgtac caattacaaa gggaaatgtg tttagaacat taataatagg
    32881 aataattata attacttctg gattattaat cgcaactaac ttagctccat tatttaccca
    32941 aatggcttta aatgctagtt ttaaaatgcc tgaaggagca actatgattt caagtatttg
    33001 tgatggtgcg aatccattaa gttgggtatt tgtaaaagtt atgaactata aagttattgg
    33061 aggagtagtt tttggagtta tagctttagg aatggctatt tacaatagga atagaataat
    33121 aaatgaaaat aaaaagctat ctatagaaga ataaggttaa aacgatttta ttaaggagtg
    33181 tataggttat gaaaaaatat aaatatgatt ctaaaagata cttactcagt gttacaatac
    33241 caggattttt tatgatttta atattgattt atgcactgtt taataactat acaaatttta
    33301 atttgaatat atatagtttg ttaataattg tctgtactta tggtatattc aatactttta
    33361 tatcatcaag taatcctaaa aaaattatta ttgacagcaa atgtatacat tttacctcat
    33421 ttatgactac acataagtat gaaattaaag atatagaaaa gataagaata agagaatttt
    33481 ataataaaaa aatttatcta aaaattaatg atggaaaact tttcaaaggt aggtattgga
    33541 taagaacaaa tatgtttaat aatagtatag cattatatag ctatttcatt gagttggaag
    33601 agtgcttata tccagattca ctaaaattta gaaataaaaa atttgagaat aagaatatat
    33661 aaaaataaaa aattgaattg aagcctaact taatcttttt tgataagata taagtttgaa
    33721 ctttatacta aatttttaga attttcaatc aagacaataa cataatagct aagcaattag
    33781 aacacaacta agatgtataa ggcatgcata tgatgaatgg gaggatttaa ttaatgttat
    33841 tagagaaatt aagaaaagaa gtattacaag catctttaga ccttttaaac tataatttag
    33901 tgacattaac aggaggaaat gtaagtggga gagatgaaca aactggctat atagcaatca
    33961 ccccaagtgg aatggattat agaaatctta caccaagtga tattgttata gtagatgtag
    34021 atggaaatat tatagatgga aaatggaaag catcagtgga tttatcagac cacttgtata
    34081 tatataagca tagagaagac ataaatagta taattcatac acattctaca tactcaagtt
    34141 gttttgctat tttaaatgaa cctatagaat gcgcaagtac aactcttgca aatgaagtag
    34201 ggggttcagt accagttgca aaattttcac caccaacatc taaaaagatg ggaaaatgtg
    34261 ttattgaagc aattggtgac aaaagagcat gtcttttagc aaatcatggc gtaattgcag
    34321 ttggtccatc tgtaggacat gctcttacag ccgctgtaat gttagaagat tcagcaaaag
    34381 tatattactt agcaaaatca attggcacac cagtgctact gcctgatgaa gaaattcaaa
    34441 gagcgagaga tgtatttttt aatgtctatg gtcaggataa ataaattaga taaaatttta
    34501 aaagtaatat gaaaatatag atattcaatg atattaagga gatttataat gatataataa
    34561 gtttaatagt taagaagtaa aatatgaaat gtaatagtat ataaattcat ttaagactaa
    34621 aaataataag ataaaataaa aaggagtctg tatttctatg tattacttat taaacaaaag
    34681 cacaaatcct tactttaatt tggcattaga agaatatcta tttttaaatg ataaatataa
    34741 tgatgatatt ataatcatat ggagaaatga agactccatt tttataggta aaaatcaaaa
    34801 tccatatcag gaagtacatc atgatgttat tgaaaaggga gaaattccta ttttaagaag
    34861 aatatctgga gggggcactg tttatcatga tttaggtaat atcaatatgt cattcataca
    34921 aaaagatagg caacttcatg agatagattt tttggagcat actaagttta tgcaaaagat
    34981 gctttcaacc ttaggactag atgtatctat aactgaaaga aaagatttat ttttaaatgg
    35041 gaaaaaaatt tcaggctctg cacagtctat aaaaagaaaa aattctcttt atcatggaac
    35101 tcttctttac gattcagatt taaataaatt aactaaatat ttaaattcaa ataaagcaac
    35161 tgaatcaaat gcaactaaat ctgtttcaag taaagttaca aatattaagt ttttactcga
    35221 aaaagatata aattactttt tagattattg tgttgaatat ttaaaatcta atataaagaa
    35281 tataaaagaa cttgaattgg atgaagaaga tattaaaagt gtatacaata taggagaaga
    35341 taaatataga aagatagagt ggacatatgg taaaacgccg aaatttcaag tagtgctacc
    35401 atttaataat gaaagtaaaa taaatataca tgttaacaga tggaaagtat caaaattttt
    35461 tatttcttat gatgataatg taattaatat ggataagttg ttagatttga atttctttaa
    35521 agaagaaata aaagagagta ttttagaaaa ttatccacat tacatagatt taatcaattt
    35581 aatattttaa tataaaacct ctaatttgat aaaattgtct tatatcaaac tagaggtttt
    35641 taatattctt gcatattaac aaccattaca aaattgtaaa attaaaaaca acactattga
    35701 aaaatcaata tatattgtaa taaatatatg tgtttttcat tagcaaatag acattaacta
    35761 tttatacaac tgaaaattta atatataatt aatcagatgg ttaaaataaa aatattaaaa
    35821 gttttaataa atgatggtta aaaataaaat acgaggtgat accatgtaca gtgttataat
    35881 tgttgcagcg ggaagcggaa ggagaatgaa cttagatata aacaaacagt tcataaaatt
    35941 aagagaaaaa gaaattattg ctcatacaat tcaagttttt tatgaaaata taaatataga
    36001 tgaaatagtg gtatgtataa aaaaagaaga agaggatttt tttaaagaaa atataataaa
    36061 taagtataac tttaaaaata taaaaatagc atatggcgga aaagaaagac aggactcaat
    36121 atataatggt ttaaaaaaat tagatgaaaa ttgtgatata gtacttatcc atgatggagc
    36181 aagaccattt gtcgaccata gaataatcaa cgaatctata aaggtagcta aagaaaaaaa
    36241 ggctgtggtt gtaggtgttc cagtaagtga tactataaag atagtgtcag atggaacagt
    36301 acaagaaact ccagaaagaa atttgttgtg ggcagcacaa acccctcaaa cctttgaata
    36361 taatctcata atagatgctt atgagcaagc atataagaac aattattatg gtactgatga
    36421 ttcaatgttg gtagaaaata taggtcaaag tgtcactatg gtaatgggtt cttatgaaaa
    36481 cataaaaata actagtccag aagatttaaa tatagcagaa caaatattaa atatggaaaa
    36541 aagagatgaa gttaacagta gaaggagaat tatatgagaa taggattagg atatgatgta
    36601 cacaaattaa cagagaatag aaaacttata atcggtggtg tagagatacc acacgataaa
    36661 ggtttgttgg gtcattctga tgctgatgta ttgatacatg caataatgga ttctatttta
    36721 ggtgctctag cattaggaga tattgggaag catttcccag atacagatga agaatataag
    36781 ggagcagata gtatgaaatt attagaacat gtgtataatc taataacaag taaaggatat
    36841 aaaattggta atatagatag tactataatt gctcaaagcc ctaagatggc tccatatatt
    36901 gagagtatga gaagtaatat atcaaaagtt ttaaacacag acattgataa tataaacata
    36961 aaggcaacaa cagaagaagg tcttggtttt acaggagcaa aacagggaat agcttcacaa
    37021 agtatttgtt tattattgtt gacaagtcag aataattaat atattattag taataagttt
    37081 aatggatatc aagtaatggg cctatataga atatctataa tgtatgaatt taagtgaaat
    37141 taatataaat ataaaattag ctatgataaa gaaatagtaa aatgatgaaa tcttcacaga
    37201 gagaaaacgg tggtgagagt tttcaagagg aagtctttga acctgtcttt tagcttaaag
    37261 ttataaaaat ctttacggta ggaaccgtta tattcccaaa agagagctat tcatatagct
    37321 aactagagtg gtaccgcgga aattaaacct ttcgtctcta tacttgtata gagatgagag
    37381 gttttttata ttttcaggaa gttaatattc aggaggaatc tattaatgaa aatgtcaaaa
    37441 atgtttatgc cgacattaaa agaaatccca gcagatgctg agattacaag ccatcaatta
    37501 atggttaggt caggcatgat aaaaaaaatg acttcaggtg tttataacca attaccaatg
    37561 gggttaagag tgttcaaaaa aattgaacaa ataattagag aagaattaaa taaaaaagat
    37621 tgtcaagaaa tactttgtgc agccttactt ccttctgaat tatggaaaga gtctggaagg
    37681 tggactgcta tgggtgaaga aatgtttaga ctaaaagaca gaacagaaag agagtactgt
    37741 cttgggccaa cacatgaaga agcattcact gatataataa gacaagaaat tacttcatat
    37801 aaacaattgc cactgaactt gtaccaaata caagtaaaat atagagacga gagaagacca
    37861 agatttggtg ttatgagaac taagactttt acaatgaagg atgcatatag ttttgatgta
    37921 gatgataaag gtttagataa gtcatatcaa gatatgtttg atgcatatgt aagtatattt
    37981 gatagatgtg gattggagaa tagccctgta caggcagatt caggagctat aggaggttct
    38041 acatcagccg aatttatggt taagtcagaa gttggtgaag atgaagttgt attttgtagt
    38101 ggatgtgatt atgcagccaa tgtagaaaga gcagaatctt gtaatctagc atcacaaaaa
    38161 gaagaaatga aagaattaga agaggttcat acaccaggag cagctacaat aaaagagtta
    38221 gaagaatttt taaaaacttc tccagataag tttgctaaaa ctttagtata tgaggcagat
    38281 ggaaaaacag ttgtagtcgt tgtaagagga gatagagaag ttaatgaaat caaagtatct
    38341 aatgctatag gttctgttat agaatttgct cttgctacag atgatgtagt gagaaaagta
    38401 actaatgcag aagtaggatt tgcaggtcca ataggtataa atgctgacta tgtatttata
    38461 gataaagaaa ttgttgaaca aagaaacata gttgttgggg ctaataaaac tgagtaccat
    38521 ataaaaaatg ctaactatgg aagagatttt gaaggaatag ttggagattt tagaaatgtt
    38581 caagaaggcg accagtgtat agtatgtggt aagccacttg aaatagctag aggtgttgaa
    38641 gtaggacata tatttaaact aggaactaag tactcagaat ctatgaatgc aaacttcata
    38701 gacaaagatg gaaaatcaaa gcctatagta atgggatgtt atggaatagg tgttgaaaga
    38761 acagcagcag ctataattga acaacataat gatgagaaag gtataatatg gcctttgtca
    38821 gtagctccat accatgttgt gatagttcca gcaaatatga aaaatgaaga acaaatatca
    38881 atagctgaaa atatatataa tgatttgcaa gctatgggtg tagaagtttt attagatgac
    38941 agagatgaaa gaataggtgt caaattcaat gattcagaat taataggaat acctatgagg
    39001 attacagtag gtaaaaatat taatgaaggt aaagtagaat ttaaacttag acataaagaa
    39061 gataaagaga taattgacat agaagaaata aatgaaaaag taaaggcaga gtttatcagg
    39121 aataatgtta ggttaggata ataacttaaa taagatattg tatagataat caaagttgta
    39181 ctttatagac accattttat ctatatataa ggatataaaa tggtgttttt ttataaaaca
    39241 aataaataag gaggtaattg aaatggcaaa aaatgaaaaa caatttgttg aagaaataac
    39301 aaagatggaa gatgattttc cacaatggta cacagatgta ataactaaga ctgacttagt
    39361 tgattatgca ccagtaaaag gttttatggt tgtaaagcca tatggatatg cattatggga
    39421 aaagatgcaa gaatttatgg ataaaaaatt taaagaaact ggacataaaa actgttattt
    39481 tccattatta ataccagaga gtttattaaa caaagaagca gaacacgttg aaggttttgc
    39541 tccagaagtt gcatgggtaa cacatggagg aaataaaaaa ttagaagaaa gattatgtgt
    39601 aagacctact tcagagacta taatatgtac aatgtatgcg aaatggttaa aatcatatag
    39661 agaattacca tatctttata atcaatggtg ctcagttgtt agatgggaaa aatcaactag
    39721 acctttctta agaacatctg agtttttatg gcaagaaggt catacattac atgaaacagc
    39781 agaagaagca caagaagaaa caatacaaca attagaagta tataaagcgc tatgtgaaga
    39841 attacttgca atgccagttg tagctggtca aaaaagtgaa agtgagaaat ttgcaggtgg
    39901 tgaaagaaca tatactatag aagctatgat gcatgatggt aaagcattac aatcaggtac
    39961 aagtcacttc ctaggtcaac actttactaa ggcttttgat attacttttg cagatagaga
    40021 aggaaattta gctaatccat accatacatc ttggggagca tctacaagac ttataggtgg
    40081 acttataatg actcatagtg ataacagagg tttagtatta ccaccaagag tagctccaat
    40141 tcaagttgtt atagttccta tagctgctaa aaaaggaaat gtaatggaga ctgttgataa
    40201 aatatatgct gatttaaaag ctaagggagt agccgtagaa gttgatgata gagataacta
    40261 tacaactgga tggaaattta atgagtggga aatgaaaggt gttccagtaa gagttgaaat
    40321 tggaccaaaa gatatagaaa ataatcaagc tatggtattt agaagagata ctttagaaaa
    40381 ggattctatg cctttagaag gattagctga tgctatatgt gatttatttg atgttataca
    40441 caatgatatg tttgaaaaag caagaaaaca tagagaagac aatacatcta tagttgaaaa
    40501 tatggatgag tttagaaaag ctttagaaga aaagccagga ttcataaaga ctatgtggtg
    40561 tggagatgca gaatgtgaag ctaagattaa ggaagaaaca ggagcaacta taagatgttt
    40621 accttttgaa caagaaaact taggtcacaa gtgtgtgtac tgtggaaaag aagcagatag
    40681 tatggtagta atggcaaaag cttactaaaa tacatttaaa taaaaactgg ggtagaaagt
    40741 atttaatact ttatcccagt ttttttgttt tttatgagta ataaaatgta tttgtaacta
    40801 tgtcataaga taagtcatag atacttatat taaaaagaat ataatagaga actattttta
    40861 ataattacat attaatgaaa gcaaaatatt tttgttatat agattttcaa taaagcgaac
    40921 aataaatata aatgaatatt aataaggagt gcttttaatc tttagaaaat aaatgactta
    40981 aaagaaagat ttatgaaatt aaaactagga ttttctgata taataaacat gtgtattttt
    41041 aaataaaaag gatattatta ttagatttga ttaaaaataa acttgcaaaa caatgtacta
    41101 gtttaatatt atagttatat tgaataaaat atcaggagga agtaaaaatg aatgtaagag
    41161 taaggtttgc accaagtcca acaggatttg tacatatagg tagtttgaga actgctttat
    41221 ataactattt atttgcaaaa aaaatgggcg gagaatatat attaagagtg gaagatacag
    41281 accaaagtag attagtagaa ggtgctatag agaatatgct taatgctatg aaatgggctg
    41341 gtgtcaacca tagtgaaggt gttatattag atgatagtgg aaaagtagta caaaaaggag
    41401 aatatggtcc atatattcaa tctcaaagat tagatatata ccaagaatat ataaagcaac
    41461 ttttagatag tggaaaagct tattactgtt tctgtacaaa agaaagactg gatgaagtaa
    41521 gagatgctca aagagcagca ggagaaacag ctaaatatga tggtcattgt aagaatcttt
    41581 ctaaagaaga agtagaagcg aatataaaag caggaatacc atatgttata agattaagat
    41641 tgccagagaa tcatacaatt aagtttacag acttagttag aggagatatg gaatttaata
    41701 ctaatgacct agatgaccaa gtattaatga aaacagatgg atttccaact tatcattttg
    41761 cagtagttgt tgatgactat ttgatgaaaa ttacacatgt tataagagga gaagaatggg
    41821 tatcatctac tccaaaacat gtttatttat atgaagcttt tggatgggaa gcacctgtat
    41881 ttgtgcattt accaaatata cttaataaag aaaagaaaaa attaagtaaa agacaaggtg
    41941 atgtagctgt tgaagacttt aagaaaaaag gatatttacc agagggatta gtaaactatg
    42001 tagcattagt tggttggtct cctgaagata atcaagaatt gtttacaatg gaggaattag
    42061 aaaaagcctt ctctgtagaa agagtatcta aaagtggtgg agtatttgat actgaaaaat
    42121 taaattgggt taatcagcac tatataaaag atggtgatga tgcttatcta acagacttag
    42181 caataccatt tttaatagaa gatggattta taacagaaga agaagctact aataaatatg
    42241 atttcttaaa gagtatgata tcagtactta aagagaaatt acaatatgta aaagaagtta
    42301 ctgaacatgc aagtatattt tttggagata aaatagaggt agaaactgaa gagggaagag
    42361 agttcttaag attagaacat atacctactt taatagatgc tttgagagaa aaaatagaaa
    42421 aaacagaggt attaaatgct gagtttgttc aagctatgct taaagaaata caaaaagagt
    42481 acaaaataaa agggaaaaat ttatttatgg gctcaagaat aattttgaca gggcaaatgc
    42541 atggtccaga tttaccaaaa gtaatggaag ttttaggaaa agaaacttgc ttaaatagaa
    42601 tagcttatgt aaaaaataat atattatagt cataaaagtc cgctaattta gaagcggact
    42661 ttttttgtgt tagtatttgg tgaaaatatc tccttaagaa aatgaaggta tttaaggtaa
    42721 taaatttaat atataaaaaa caaagcaaaa atataaataa aatatgaata ataaactaat
    42781 aaaatattaa gcatagaaga agggaatcta ttattttagt ttgatttaat tattaagggg
    42841 gtaattacta tgtatagtaa tattgatgat gttaaaaagg aattaaagga gctatgctta
    42901 gaatatgtta caattttaga aaaattaaaa gatgaaaaaa tgattacaga agaaactttt
    42961 gaaaagtgct cttctcaaaa aaaaatattt ttagaagaac aatagaggat ggtaatagta
    43021 ttattattat gtagtttgaa agatagtacg aaaaatgata gtaatactat tatttattgc
    43081 aattttcaac tataatataa tatataatgt taagaagata atttataaaa atacagtgag
    43141 gtgatgagtg tgaaagttta taatacattg actagaacaa aagaagaatt tgttccatta
    43201 gaagaaggaa aggtaaaaat gtatgtgtgt ggtccaacag tttataacta tatacacata
    43261 ggtaatgcaa gaccatttat aatatttgat actctaagaa ggtatttaga gtatagagga
    43321 tatgatgtaa cttatgtaca aaactttaca gatgttgatg ataagattat aaatagaagt
    43381 catgaggagg gaatatctcc tgaagaagtt gcggctaagt atataaaaga atattttgta
    43441 gactgtgatg ggctaggaat aaaaagagct actgttcacc ctcaggttac agataatata
    43501 caacagatta tagagtttat aaaagagttg gaagataagg gatatgcata tgcagtaaat
    43561 ggtgatgtat attttgatac aaataagttt gaaggttatg gaaaactttc aggtcaaaaa
    43621 caagaagatt tagaggcagg ggctagaatt gaggttaatg accaaaaaag acatcctatg
    43681 gactttgttc tttggaaggc aaaaaaagaa ggtgagccag gatgggatag cccttgggga
    43741 gaaggtagac caggatggca tatagaatgt tctgttatgt ctaagagata tttaggtgaa
    43801 acaattgata tacatgcagg tgggcaagat ttaacattcc cacatcatga aaatgaaata
    43861 gctcaaagtg aagctagaag tggaaaaaca ttctcaaaat actggatgca taatggatat
    43921 ataaatataa atgatgaaaa gatgagtaaa tcaaaaggta atttctttac agtaagagat
    43981 atatcaaaat tatatgattt agagatagta agatttttca tgttatcagc acattataga
    44041 aatccagtaa actttagtga tgagatgtta aatcaagcta aagcaggtct tgaaagacta
    44101 tataatacta aagaaaaatt agaatttacg ctaagtaatt tagtagaatc tcctttaaca
    44161 gaaaaagaag tagagcttgt taaagaatta gatgacttta gacaaaaatt catagatgct
    44221 atggatgatg atgttaatac agcagacgca gtaagtgtaa tatttgaatt agctaagtta
    44281 ataaattcta atgtagatga aaattcttct ttagagtttg ctaaaaaatg cttagatgaa
    44341 tttaatgaac ttacaggagt attaaatatt gtaaataaga aaaaggatac tgtattagat
    44401 aaagacattg aagaattgat acaaaaaaga actgatgcaa agaaaaataa agagtttcaa
    44461 ttagctgatg atattagaca acaattacta gatatgggaa ttgtattaga agacacaaga
    44521 caaggtgtta agtggaaaag gatataaaaa tggaaaaaac tgaattagtt actatgtcac
    44581 cattagtttt agcatactta ggtgatacag tgtatgagac atatataaga gaatatttaa
    44641 ttagacagaa tacacaaaga aaagttaatg atttgcataa actagctata aagtatgtaa
    44701 aagctaaagc tcaggcaact ataattcatg aaattgaaat tgagttaact gaagaagaga
    44761 gtaaaattta taaaagggga agaaatcaaa agtcaaatac ttctcctaag aatgcagata
    44821 ttatagacta caaacatgca actgggtttg aggcattagt gggatatttg tatttaaata
    44881 atgaaataga gagacttcaa tatattatca ataaaggaat caaaattatt gaaagagata
    44941 tgtaaatatt aaagagtgtt gtcttaataa taagtaataa ggcaacactt tttttataac
    45001 taatgtataa taaatatata gaaattagta atgagaaagg ataaaaagtt atgaaagtaa
    45061 aattaatatc acatacacct gaaccagaaa aagtaatagc tatggcagct aagctatgtt
    45121 attcaccagt tgggacagac gaaatagaaa aagacttaac agatgaaagt atagagaaat
    45181 ttttaaatat gttattaagt ataggtcatg ggtcaatatt agaacatgct tcatttacat
    45241 tttcaataga aggtatttca agggcttgtt cacatcaaat tgttagacat cgtatagcta
    45301 gtttttcaca acaaagtcaa agatatgtta aattagaaca atttgagtac ataattcctc
    45361 cagaaataga aaaaatagaa aaggcaaaag agttatttat agactccatg aaaaaagacc
    45421 aagagaatta tgataagtta gttgaaatat tgtttgaaaa tcattataat gacctaataa
    45481 aaaacggtaa aaatgagaaa acagctaaaa gacaagctga aaagaaagca atagaagatg
    45541 ctagatacat atttccaaat gcatgtgaaa caaaaatggt atttactata aatgctagaa
    45601 gtttgtttaa tttctttgaa catagatgct gtgaaagagc acagtgggaa ataagaaatt
    45661 tggctgtgga gatgttaaga gaggttaaaa gggttgctcc tatattattt aaaaagactg
    45721 gtccaagttg tgtaaatgga agttgtccag aaggaactat gacttgtggc gatatagttc
    45781 aagttagaga aaaatttaag gccttgtagg aggtgaataa tttggcgagt atagaaggaa
    45841 gaaatccggt aatagaagca ataaaaagtg acagagaaat agataaaata ttaattgcaa
    45901 attcatctaa agaaggttca attaagaaaa taataggaat ggctaaagat aagaatataa
    45961 ttattcagta tgttgataaa cataagctag atgaagtaag tacaagtcat tcacatcaag
    46021 gtgtaatagc ttatgcaagt gagtataagt attatgaatt agatgagcta atagatttag
    46081 caaagaataa agatgaagac ccatttttca ttatattaga tgagataaca gacccacata
    46141 atttgggttc aataataagg acagcagatg cagtaggagc acatggagtt atcattccaa
    46201 aaagaaggtc tgtacacata actcctgtag ttgccaaagc atctgctgga gcagtagaat
    46261 atatgccagt ttgcaaggta accaatatag ttaatacaat aaaaagattc aaagaagaag
    46321 ggctgtggat tgctgcagct gatatggatg gagaaacttt ttataaacaa aatcttactg
    46381 gtcctcttgg tgtagtaatt ggaagtgaag gttttggaat atctagattg gttaaacaaa
    46441 actgtgactt tatagtaaaa atgccaatga taggtaatgt tacatcttta aatgcatctg
    46501 tagcaggtgg aatactttta tatgagatat tcagacaaag actggataaa agtaaatagg
    46561 catgaaaaaa aatataaatc attacttaat aatagatggc tacaatatta taaatgcgtg
    46621 ggacaatttg aaagaactgg ctaaagagga cttagaagat tctcgagaaa agcttattga
    46681 tgacattata gaattttctg agtttatggg ttataagact ataatagttt ttgatgctta
    46741 taatgttaaa aattctcgag aaaaagttga aaaaagaaaa cacataacaa tagtttatac
    46801 aagagaacac caaacagcag atagttatat agagaaattt ataacttctt tatcaaagta
    46861 tgatgatgta aaagtagcca ctaatgacta tgcagaacag caaatgattt taggaaaagg
    46921 tgctactaga atgtctgcaa gagaattaaa gttagagtta gatcgttcca agaataaaat
    46981 gaaggaaaaa aatatcggtt tgaggaaaaa aattcagcga aattggttgg aggaaaggtt
    47041 agataaagaa acattgtcga aacttgagaa cattcgtaga aagcgttgaa attactagct
    47101 tctttagact ataatatacc tataaatttg ttttatatat gggggagatt tacatgttgg
    47161 tagcaaaaga aaaaagttat gagttagtgg acaattgtca gcaggatgag tataacattg
    47221 tattaagagc aagtgaaggg gataaaatag cactagagta cattattact aaatacagaa
    47281 attttgtaaa ggcaaaagca aagtcatatt ttttaattgg agcagataaa gaagatataa
    47341 tacaagaagg aatgataggc ctttataagg cagttagaga ttttgatgga agtaagacca
    47401 attcatttaa atgttttgcg gagatatgta taacaagaca aataataact gctataaaaa
    47461 ctgcaacaag acaaaaacat atacctttaa attcatatgt ttctttgaat aaaccaatat
    47521 atgatgaaga gtcagacaga acacttttag atattatagc tacaagtata gtaacagatc
    47581 cagaagagct tataattagt aaagaagagt taaaaaatat agaatcaaaa atgaacgaat
    47641 tgttaagtga cttggaatta gaagtactag aattatattt aaatggaaag tcataccagt
    47701 ttatagcgga caagcttaaa agagatgtaa agtcaataga taacgcttta caaagggtta
    47761 agagaaaatt agaaaaacat cttgaaaaca gaaatgatta atagtaaaat acttaccata
    47821 agcttattgt gagcaaaatt aatttatatc gaaagataag ggaggaaatt caaaatggct
    47881 aaagctaaat acgaaagaac aaaacctcat gttaatatag ggacaatagg acacgtagac
    47941 cacggtaaaa ctacattaac agcagcaata acaaaaacat tatatgacag atatcaatta
    48001 ggagaagcag tagatttcgc aaacatagat aaagctccag aagaaagaga aagaggaatc
    48061 acaatatcaa cagcacacgt tgagtatgaa acaccaaata gacactatgc acacgttgac
    48121 tgcccaggac atgctgacta cgttaagaac atgataacag gagcagcaca aatggacgga
    48181 gcaatattag tttgttcagc aacagatgga ccaatgccac aaacaagaga gcatatacta
    48241 ttatcaagac aagttggagt accatatata gtagtattct taaacaagtg tgacatggta
    48301 gatgatgaag agttattaga gttagtagag atggaagtaa gagatttatt aacagaatat
    48361 gatttcccag gagatgacac tccaatagta agaggttcag cattaatggc attagaagat
    48421 ccaaagagcg agtggggaga taagatagta gaattattcg agcaaataga tgagtatata
    48481 ccagctccag agagagatac agataagcca ttcttaatgc cagtagagga tgtattctca
    48541 atcacaggaa gaggaacagt tgcaacagga agagtggaaa gaggagtact aaaagtacaa
    48601 gacgaagtag aattagtagg attaacagaa gcaccaagaa aagtagtagt aacaggagta
    48661 gagatgttca gaaaattatt agaccaagca caagcagggg ataatatagg agcattatta
    48721 agaggagtac aaagaaacga gatagaaaga ggacaagtac tagcaaagac tggatcagta
    48781 aaggcacaca caaagtttac agcagaagta tatgtactta aaaaagaaga gggtggaaga
    48841 catacaccat tctttgatgg atatagacca caattctatt tcagaacaac agacgtaaca
    48901 ggagcttgta agttaccaga aggaatagag atggtaatgc ctggagataa cgtaacaatg
    48961 gaagtagact taataaactc aatagttgta gaagagggat taagattctc aataagagaa
    49021 ggtggaagaa cagtagcttc aggagttg
//
LOCUS       DACTZW010000025        47715 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.025, whole genome shotgun sequence.
ACCESSION   DACTZW010000025 DACTZW010000000
VERSION     DACTZW010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 47715)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47715)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47715
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.025"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            84..272
                     /gene="rpmB"
                     /locus_tag="JAM15_07370"
     CDS             84..272
                     /gene="rpmB"
                     /locus_tag="JAM15_07370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002842707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HAT6798066.1"
                     /translation="MAKVCSVCGKGKVSGNQVSHSNKHNKRTWSANLRSVRAIIDGAP
                     KRVKVCTRCLRSGKIERA"
     gene            complement(432..584)
                     /locus_tag="JAM15_07375"
     CDS             complement(432..584)
                     /locus_tag="JAM15_07375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate translocator"
                     /protein_id="HAT6798067.1"
                     /translation="MRNNKSKVLLGILCLATGMAVILSMLLPGWIWSALTALILIGCG
                     ALLFFC"
     gene            complement(682..1158)
                     /locus_tag="JAM15_07380"
     CDS             complement(682..1158)
                     /locus_tag="JAM15_07380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HAT6798068.1"
                     /translation="MNLKRSNEKREEYRRMYSDKESFLSLIQNFTSVSIAKELTLKNI
                     ELETSFICEYKGKEVDIIYKVFSKSGKVSHYIVLEFQTEMDTEIVPRLKSYREQIWKS
                     FIMKKSLEEIEDKNFKLPKVIPVVLYSGPERLSRKKGILDIVESISEFSNNSSMKN"
     gene            1377..2138
                     /locus_tag="JAM15_07385"
     CDS             1377..2138
                     /locus_tag="JAM15_07385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAT6798069.1"
                     /translation="MEYTVQKLSKLAGISTRTLRYYDEIGLLKPLKINSSGYRIYGQN
                     EVNKLQQILFYRELGINLENIKNIINSPNFDSLSALKEHHNKLLAKRKQIDLLIENVT
                     KTIALKEGKYTMTDIEKFEGFKEKMIDENEKNYGTEIREKYGKDIIDTSNKKLKNMSK
                     QDYENWQNLNIEIISKLKKAFKTGDASSELAQEVAKLHHKWLSYTWNTYSKEAHSSLA
                     QMYVYDERFTSYYDREQPGLAKFLRDAIVIYTRDK"
     gene            complement(2398..4326)
                     /locus_tag="JAM15_07390"
     CDS             complement(2398..4326)
                     /locus_tag="JAM15_07390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HAT6798070.1"
                     /translation="MHKRLLTLFKLLNESDDKITCKTLSSHLKVSERTIRNDITSING
                     TLEKNGAIIKIKKGEGYYIDILNLALYQQYLALISDDIMDSSEIPDSPIERNQYILKY
                     ILYNNTYIKLEDLANSLYVSKFTILNDIKRIKPILSKYNLILVSKPYYGVKVEGKEID
                     IRRCISNNMINRNFENYIIGITDREIELFNNVDLIELQRVVLSEINKFNINFLDFNLK
                     NFIIHLAITISRILDGYCLDNVLDVVLTDFQSNTTVENIFNYIESKYTIIISKADRVY
                     LYNHFITKSSLLDNVSNRVDTKIIEYVEEILEVINNQYTFDLRNDSVLFDDLVLHFKS
                     ILNSKSYNLNKVNPLINTIKSNYPLAFEITLNAIEKVFKNSIYSLTEDEIGYVSLHIG
                     AGIERFFQNNIKCKNVVLVCGSGYGSSRLLEVQLNKVFHDKINILQCLSFNQFLASEL
                     SDVDIIISTIPLNHDSIPIVLVDLKLLKKDIENISKSITNNSHIYSNLLDNFFDKNLF
                     IVNPKIKDKDELIKLMCNKLTQSEIVFPSFAESVFYRESLSSTNIDDFLAIPHPMELS
                     SIRTKICISILNEPIYWSEDSTVKLIMMLAINKDDYIKINSIYDILLKIIHDNDIRDS
                     ISNCNNFDNFLSIIKSIV"
     gene            4560..5012
                     /locus_tag="JAM15_07395"
     CDS             4560..5012
                     /locus_tag="JAM15_07395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAT6798071.1"
                     /translation="MVLQEKYIFIDKDLKSKEEVLNFIADSAYILGITTNKEALLKDL
                     LKRENEFPTGIKDGFAIPHTKSVNVKEASILYIKTTNELEWKTLDDSKVRYVFSLLAP
                     HKNEGNIHLKTLSKLATCLMEDDFTSEVKNASDASHLVKYITNKMKEE"
     gene            5015..5323
                     /locus_tag="JAM15_07400"
     CDS             5015..5323
                     /locus_tag="JAM15_07400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HAT6798072.1"
                     /translation="MKIVAITSCIAGLAHTPMAAKALEQAASKMGHEIKVEQQGAMGR
                     VNTITKEEAQDADFILIASDQTISGMERFDGKKVIKVKIGIALKKPEAVLTKCIEAIS
                     "
     gene            5437..6543
                     /locus_tag="JAM15_07405"
     CDS             5437..6543
                     /locus_tag="JAM15_07405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HAT6798073.1"
                     /translation="MSKKNKSLLSELKGHLMTGISYMLPLVIGSSLVVAIPKLTALAM
                     GITSLDAYKNVSGFYHILYLMEQVGWTGIGLLNTVLAGFIAFSIGEKPAMGAGFIGGL
                     IASNTNAGFLGAVIAGFFAGYVCKFLKKKIKISGSASGMMPLIIMPLITVGLTGFLMS
                     VVLAGPLGNINTSLNAWVAEMCQNGTNSVVLALILGAMIGFDLGGPVNKAAWMAGNAL
                     LLEGIYLPAILVNCAIVIPPLGYGLAKFIRKSKFSNALAETGKGNIVMGIIGITEGAI
                     PFTLTNPLKLVPVNMIGCALGVGLSALLGVHAIMPPVGGLYGFISIGSGWAYLVGAIF
                     GALVIAILSTTLVDFNEDETTENTEFDEIELDIM"
     gene            6618..9296
                     /gene="mngB"
                     /locus_tag="JAM15_07410"
     CDS             6618..9296
                     /gene="mngB"
                     /locus_tag="JAM15_07410"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HAT6798074.1"
                     /translation="MKKTKVHVVPHSHWDREWYFTTSRSKIYLMKDFQDILDILEEKE
                     DFKYFTMDAQASLLDDYLKWRPQDEYRIRDLVQRRRLVIGPWYTQTDQLVISGESIIR
                     NLYYGIDRCNEFGEPMRVGYVPDSFGQSAQMPQIYRGFGIDSSLFWRGVSDDMVDTTE
                     FIWKGSDGSKVLAVQIPFGYYYGGNIPEDDSDLKEYLKDIIGKLKVKASTNNVYFPNG
                     FDQAPIRKNLPDILKKANEIDNENEYEISNIENYIDSVKNERNEFTELKGEFLNAKHM
                     RIHKSIFSSRSDLKIMNNKLENYITNVLEPLLTLSYSLGNEYPHLVIKDIWKLMFENA
                     AHDSIGSCNSDTTNEDVYTRYKQARDLSINLLDLHMRLISTQIKNNNEEITLTVFNGF
                     PEVRNEVIEFDTYIPGQDFVIKNKNGEILNYIIKEKEDITNYILTQTIRLNPSKKIYI
                     PKTVYRAKIALSVKDIPPMGYTQLVFELDTKNKCEIETSNCKEIENKYYKITANKNGS
                     LEILDKESSKTYKNQAVIEDNGDDGDSYNYSPPRKDIYVSSLDSVSSVEVLKSNIQEE
                     MILKYSLTIPASLEERSIGKVSVKMPVTMKITLEPKEQIIKFNVNIKNNQALSHRVRV
                     LFNTEIASKFSIADQQFGIIQRPTVLEKDLALWKRDNYSWQEKPITIEPMQSFVTLED
                     GQRGIALITGCVREYQIVGDNLDTIALTLFRSFGYMGRENLLYRPGRASGEKIIATPD
                     AQLLKELNFDFGLYIYNNKFDEANVANTAKRFLTPIQIYEYADFLNGRLIFAFNDEKQ
                     IYENEFSLMNVNNSNFTVSAIKKEEKGDGIVVRIFNGMKNEDAKGSLNINKNVNDAYS
                     AMLDEIYDNNSKLKVNTKTVEVNSLSHCKVQTIVIK"
     gene            complement(9613..11946)
                     /locus_tag="JAM15_07415"
     CDS             complement(9613..11946)
                     /locus_tag="JAM15_07415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAT6798075.1"
                     /translation="MDTKLKKFKDKYIVTIIVFILMLSASLGMISQYSTIQAGAKGGA
                     KNPFEQESFVDSIYKGSYVLYHNMKEEQEGKMIQPSKLFINEETMNYIKNVSKEKDTY
                     DGSETYYTDDSINADFNENFENWEHFIKASGKNLKYYLVDKESNFEFFNDNKELGVLD
                     TTKNDASKENSDENQSKNTEMNDEERQKQITDIKENYRFYVVMNFDKDGKVNIVDSYG
                     VNQKVINQMLLSKAREDLMDTSLGGNSISYKLSPIKNITLVYAVPKVISKGDSVEYGY
                     GNTYFDDGIISYISNVENNSYYKISGMILKIILAIVVIVALAFPYRKSKELLGFDTLL
                     RIPLEILFIALAIIQGLVDLYPTVIISNTLSGNYVEYLINNDISAKMASILVSLMNLT
                     YWFVIFSIIFVFIILLKHILNVGIREYFTKHTVTGMFFVWLKKAGKTVINQIRTINLK
                     EKPNKTIVTILGINLLIIVIMCSMWFFGIILALIYSVVLFKILSDYSKKTIYEYNQLL
                     DVTKKISDGNLDVNMEKDLGFFNPIKDELGNIQTGFKKAVDEEVKSQKMKTELISNVS
                     HDLKTPLTSIITYIDLLKDESITDENRKLYIDTLDRKSQRLQHLIEDLFEVSKANSGD
                     VYLNIVNVDIVSLMKQTLLELDDKLADSSLIVKNNFSNEKIILPLDSQRTFRVFENLI
                     INISKYAMPNSRVYIDILETDNKVNIMLKNMSASEIDFSVDDIMERFVRGDKSRNTEG
                     SGLGLAIAKSFIELQGGKMNISVDGDLFKVTITFNKN"
     gene            complement(11921..12637)
                     /locus_tag="JAM15_07420"
     CDS             complement(11921..12637)
                     /locus_tag="JAM15_07420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6798076.1"
                     /translation="MNSYNILVVEDEKEIADAIEIYLLNQGYNVFKGYNGLEGLKVIE
                     NQEIHLAIVDIMMPKMDGITLTMKLRENYNFPVIMLSAKSEEVDKIMGLNIGADDYVT
                     KPFKPLELLARVNSQLRRYTKYLNMVGNKEQKVESDDSVFAIGGLELNENTKEVNIDG
                     KYIKTTPIEFKILSLLMRNAGRVFSADEIYERVWNENAVNTDTVMVHVRNIREKIEID
                     PKNPKYLKVVWGVGYKIEKI"
     gene            complement(13052..13708)
                     /locus_tag="JAM15_07425"
     CDS             complement(13052..13708)
                     /locus_tag="JAM15_07425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="HAT6798077.1"
                     /translation="MELQDTIFKRQSVRKFKNQDVSDEDILKMIKAAGAAPSGKNIQN
                     WHFVVIKRRDLMEKIADVITKKQQEILVEMDKVSVDKANRFRKFVKNFTLFYLKAPVL
                     VLVFTKVYNPSGYYELELIDAPKETIDKLFIRNPGMQSLGAAIENFTLSAIELGYGSC
                     WLTSQNYAADEIEAVLEAETGFEKGEYFLGAMLALGVPEDNLKSPSKKPVEEICTFIK
                     "
     gene            complement(13763..14392)
                     /locus_tag="JAM15_07430"
     CDS             complement(13763..14392)
                     /locus_tag="JAM15_07430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAT6798078.1"
                     /translation="MVDSIIFDLDGTLWDSTEEVCKVWQDVLSKHKEIELSVTKDLFR
                     SLMGLSFEEIANRLFPNLSEEERMNLLNECSLKECDYLSENGAKLFDDIEDTLKLLSK
                     KYKLFIVSNCQAGYIESFLKAHKLEQYFIDFECPGNTGLHKGENNKLIIERNKLINPI
                     YVGDTQGDANSAKFVGIPFIYAKYGFGNVDVYDYFIDSFKDLLEHDILK"
     gene            complement(14523..15164)
                     /locus_tag="JAM15_07435"
     CDS             complement(14523..15164)
                     /locus_tag="JAM15_07435"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HAT6798079.1"
                     /translation="MKICIVLNGEIEDYEVTRDIIIKECYDCIICADGGANHTYKMEI
                     MPDYILGDLDSVEEEKINFYKNKGVKFEKFPSKKDETDTELCLFLAKTLKANHIDFFG
                     ALGGRIDHTLANIKLLYYLKEDGIYSRILSDKEEMYIVENEEISLYGNPGDTISVIAI
                     NGDAKGVTLTGLEYPLDNYYMKYSVPIGISNVMLSNSCKIKVEQGCVLVVRNL"
     gene            complement(15173..15844)
                     /locus_tag="JAM15_07440"
     CDS             complement(15173..15844)
                     /locus_tag="JAM15_07440"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HAT6798080.1"
                     /translation="MIKLAPSILSADFAKLLEDVRKVESAGCEYLHIDVMDGHFVPNI
                     TLGPLVVKSLKKENINMVFDAHLMIENPDQYIEEFVKAGCDIITVHQEACVHLHRTIQ
                     NIKSHGIKAGVVLNPATPVDTIKHVLPDLDMVLLMSVNPGFGGQSFIPCVLDKIKELK
                     AIIDSQGLNIDIEVDGGISPKNVAEVVQAGANVIVAGSAIFGSDDIQETVNLFRKNAS
                     LEELV"
     gene            complement(15849..16733)
                     /gene="rsgA"
                     /locus_tag="JAM15_07445"
     CDS             complement(15849..16733)
                     /gene="rsgA"
                     /locus_tag="JAM15_07445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HAT6798081.1"
                     /translation="MLEGKIIKGISGFYYVDTYNGIYECKARGIFRKQKITPLVGDRV
                     KISIVDEDEKKGILEEIDSRDTELIRPPIANVDKALIVFAIKNPKPNLSLLDRFIVLA
                     EKENLETVIILTKADLDDNDTLETVKNIYELSGYKVIPVSNITKLNIDKVKEELKENV
                     VVFAGPSGVGKSSLLNEIDENFKLQTGVVSDKIKRGKHTTRHAELLKLEFGGMVADTP
                     GFSSLALEDIEEVELKDYFIEFDKFNDCKFGSKCIHENEPNCAIKEAVTNGEISKERY
                     DSYIQLLHEIRQNNSRRY"
     gene            complement(16831..17568)
                     /locus_tag="JAM15_07450"
     CDS             complement(16831..17568)
                     /locus_tag="JAM15_07450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAT6798082.1"
                     /translation="MKKKTVLITGGARGIGKAMSKAFAKEGYNVLVNFNKSENEAKEL
                     YTILNEKNFSVKLFKADISNREDVENMVDYCIKEFGGLDVLVNNAGVSQDKLFTDITD
                     EDWDNMMNINLKGSFYCSQVALKYMISEKKGNIINISSIWGISGASCEVHYSITKAGI
                     IGMTKALAKEVGPSNIRVNSIAPGVINTDMLSGYNEEDIDALVEETPLMRLGTPEDIA
                     NCAIFLASDKSNFITGQVISPNGGFVI"
     gene            complement(17676..19685)
                     /gene="pknB"
                     /locus_tag="JAM15_07455"
     CDS             complement(17676..19685)
                     /gene="pknB"
                     /locus_tag="JAM15_07455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HAT6798083.1"
                     /translation="MGDTILGNRYEIIRKIGDGGMAFVYEAKDRLLNRTVALKVLRPE
                     FVDDDEFLTKFKREAEAVASLSHPNIVNVYDVGEDGKVHYIVMEFVDGKNLKEIIQDE
                     GILDEYTALDITKQIAMALSAAHKKGIIHRDIKPHNILISNEGRVVKVADFGIAKAVS
                     NSTMTNIGSIIGSVHYFSPEQAKGKFVTNNADLYSLGIVLYEMLIGKVPFRGDSPISI
                     ALQHINDDIDFTSEEKVRIPQSVRTTIKKLTEKSSADRYQTAEELIEDIEYIEKNIDL
                     DFIKEYDDFATKKIDEKEINKVVNPTLAKPAPEKVVKPVEVADLDDDEDYYDDFYEED
                     EEEEEEEIMRAKKNQRPKSTPSKRTKKKKKKQESPKSRRRLKVIAAVLILILCAQVFL
                     AYKFLFAGGFGNKSLTVPNLVNMTLEEAQSAVEKEGLYLSVKSEEYNSEVDENCIISQ
                     TPEGGSTNVKKGDTINVVVSKGSSQASVPNVVGLTLSNAKQLIEENNLKVGTVKYEYS
                     SIYKEGTVLSQSPGAGSSRAQEGDEVNLYVSKGSEKSNTQTPTVPDKKPTTPENNTPT
                     EPGSNSGNSGGNSGSSNSGNSGGNSGNNGGNSGGSNSGNSGGSSGGSNSGDNGGSSGG
                     SNSGDNGGSSGGSNSGDNGDSSGGSNSGDNGGTSPGTGANIGKTE"
     gene            complement(19702..20454)
                     /locus_tag="JAM15_07460"
     CDS             complement(19702..20454)
                     /locus_tag="JAM15_07460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HAT6798084.1"
                     /translation="MVYSCASHIGKIRKNNEDYCEGEVIDTEHGPIGIFAIADGMGGH
                     KKGEVASKLAVENIIDFLKENLLQHDNVKIDYIDDILKQAYNNVNSIVHKKSMEDIEF
                     EGMGTTLVTAIVYNNVLYVANVGDSRCYLLTDEKFDKITIDHSVVEELMMAHVITEEE
                     ARRHPQRNRITRAIGTDDMVVVDIFKKEIKKSDIILLATDGLTGFIDDEDIRDLILDY
                     EYERTSNISEELISMANDVSGKDNVSVIVIKV"
     gene            complement(20474..21505)
                     /gene="rlmN"
                     /locus_tag="JAM15_07465"
     CDS             complement(20474..21505)
                     /gene="rlmN"
                     /locus_tag="JAM15_07465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HAT6798085.1"
                     /translation="MEKKKIVLKNFTEDELKEFMKTIDEKPFRGSQIFSWIYKGAKTF
                     DDMNNIPKSLRNKLEEVSCIGNIDIELKLESKVDNTKKYLFLLDDGNIIETVMMDYDS
                     RVTVCVSNQVGCRMGCNFCASTMDGLIRNLEPWEILDQVIKIQEDTGKRVSNLVLMGS
                     GEPLDNFENTKQFLKIINEKNGLNIGYRHITLSTCGIVPKMYELADLEIAINLALSLH
                     SPYDEERRKIMPVANAYSIEEILNACRYYIKKTNRRVTFEYSLIKGVNDSEKEAKALA
                     KLLKGMLCHVNLIPINKVEEREYEKPDKAFIYKFRDSLEKNNIPATVRMSMGSDISGA
                     CGQLRRKYK"
     gene            complement(21513..22838)
                     /gene="rsmB"
                     /locus_tag="JAM15_07470"
     CDS             complement(21513..22838)
                     /gene="rsmB"
                     /locus_tag="JAM15_07470"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HAT6798086.1"
                     /translation="MDAREVGFKVLCDIEKNDNYSNIAINKHFKNLEISDMDRGLATE
                     LIYGVIENKYYLDYIINKLSKIKVKKMSTYVKIFLRMGTYQILFLDSISDYAAVNETV
                     KLSKKYDKKSSGFINAILRNEIRAKETIMDITEEDSVKYLSIKYSYNSWIIKNWIDKF
                     GQEFAEDLLEANNEKPSIYIRTNTLKISREELIEKLSEMGIVCLKVPMVEEAIKVEKM
                     KNIEKNELFKAGLFTIQDISSMIVGKVINPKEGSFVLDVCSAPGGKSTHLATLMNNTG
                     QVVARDIFEHKLKLINSTVNRLGLKNVFVERFDASEIDENSISKFDYVLADVPCSGFG
                     IIRRKPEIKYKKEEELKDITSIQKKILENASKYVKVGGTLVYSTCTIQDVENINIVTS
                     FVEENHNFEFVPIDTVNVDLDNQDKGYLKIYPNIHGIDGFFIAKLKRIR"
     gene            complement(22900..23601)
                     /locus_tag="JAM15_07475"
     CDS             complement(22900..23601)
                     /locus_tag="JAM15_07475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HAT6798087.1"
                     /translation="MYPVYGGFWGFDPTMVVLIPAILLTIYAQFKVSSTTNKYLRVNT
                     RRGYTGEQTARRVLDSNGLYDVKIEMVRGHLSDHYDPRRKAVRLSEDVYYGTSITSVA
                     VAAHECGHAIQHAKGYAPLQIRSSLVPVVNFASSISWFLIFLGFIMAGPFLKIGILLF
                     SASVLFQIITLPVEFNASSRAIVQLGNLGIIDESESRQSRRVLSAAALTYVAAALVSI
                     LQLLRLLLIAQRRND"
     gene            complement(23670..24422)
                     /locus_tag="JAM15_07480"
     CDS             complement(23670..24422)
                     /locus_tag="JAM15_07480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF116 domain-containing protein"
                     /protein_id="HAT6798088.1"
                     /translation="MTDIKKYLTSVGILILILGILIGVVNFFIISLTQIFSLMINIII
                     ISLILIILCSTAVTYRVIKGKYVNSNIMKINFNIVSGLFPIISFIASSFGMSKSDIRR
                     IYIKLNNEYIYSNKYNFNPEDIIILIPHCIQENSCKLKVTNDIDNCKECGRCNVGELI
                     KLKEKTNVKIFVATGGTLARKIIMDNKPKAVVAVACERDLTSGIQDIKKIPVLGVFNK
                     RPNGPCVNTNVDMMDIEKAIGFLTGKNILICN"
     gene            complement(24432..25361)
                     /locus_tag="JAM15_07485"
     CDS             complement(24432..25361)
                     /locus_tag="JAM15_07485"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HAT6798089.1"
                     /translation="MKIVFMGTPDIAVPCLQKIIDEKYEILGVVTQPDKPKGRGKKLG
                     MSPVKELAIENNIPVYQPVKARDKEFIDKIKSLNPDVIVVVAFGQILPKEILEIPKLG
                     CINVHVSLLPKYRGAAPINWVIINGEEKTGVTTMYMDEGLDTGDMILKTEVNLDENIT
                     AGELHDKMMNIGAETLKETLRLIEEGNAPREVQNHEEFSYAPIMNKSLGNIDFSKSAR
                     EIHNLVRGVNPWPSAYTTYNDVIMKVWKTKVLDEKSTKDVGTIIDVSKDGIKVSTIDN
                     VLLIEEIQMPNKKRMLVGEYIKGNTIETGLVLG"
     gene            complement(25376..25816)
                     /gene="def"
                     /locus_tag="JAM15_07490"
     CDS             complement(25376..25816)
                     /gene="def"
                     /locus_tag="JAM15_07490"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HAT6798090.1"
                     /translation="MALRQIVQIGEPVLRKKSKKVEKIDEKIIQLLDDMAETMYDADG
                     VGLAAPQVGILKRVVVIDIGEELIELINPEIIETSGEQIDEEGCLSVVGEAGNVRRPN
                     YVKVRALNRNGETIELEGEELLARAFCHEIDHLDGILFVDKIEK"
     gene            complement(25834..28323)
                     /gene="priA"
                     /locus_tag="JAM15_07495"
     CDS             complement(25834..28323)
                     /gene="priA"
                     /locus_tag="JAM15_07495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HAT6798091.1"
                     /translation="MKKYAKVIVRSNTIYTDNLFTYQIPVFLSDVIKIGHRILVPFGK
                     GNKPTEAFVFQFTDSLDEKIKIKEIIDILDENPIFRKEDLELVYWMKNRYLCTYIECI
                     NLIYPKGYKLNNYKVVLLGESLSGLNEIELKEKISTLSDKNREIVEKVIDSKGKIKVD
                     KLKYIPNLNSSLYTMNKNGIIKLCWEYKNHKNEKKVCYISLSLESDKIDDYIEQNKIN
                     VGSKQKEILSFLKNNENVEINDLLDLLNASKQSINSLSKKKLITLEFKDYYREPKSIY
                     KSVLKSIKLNNEQQEAVDEIKSNMFVDDKKPYLIHGVTGSGKTEVYMEIIEFALNQGL
                     DSIFLVPEIALTPQTIDRLKSRFGDLVGVFHSKLSEGEKHDVYKAVKAGKVRVLIGAR
                     SALFAPFNSLGLIIIDECHESSYKSEKNPKFNAIEVARFMALKNNITLILGSATPSIE
                     EYYRAKSGEYKLINIKSRANDKPLPNIEVVDMKDELDKGNRSIFSLKLQKEIRYAIEE
                     NNQVILFLNRRGYANFVSCRKCGYVFQCENCDISLTYHKKSNTGRCHYCGYEKEIPKE
                     CPECKSTYVKPFGVGTQKIEEELKYIFPDIKTLRMDKDTTSKKGALDEILNKFKDKEA
                     DVLIGTQMLSKGLDFENVTLVGILSADMILNFPDFKSFETTFQLITQVSGRAGRADKE
                     GKVVLQTYDTEHYAIKHAIEYDYEGFYEDEIKIRKAFGYSPFNNMLSVVVSGEDERLV
                     IKNIKNMHASLIYLLEKRGINDLGFILGPNPCSISKINQNYRWQILFKDENIEINLLK
                     GIIKYICITKRDLIFDKNINVSIDINPNSVL"
     gene            complement(28598..29797)
                     /gene="coaBC"
                     /locus_tag="JAM15_07500"
     CDS             complement(28598..29797)
                     /gene="coaBC"
                     /locus_tag="JAM15_07500"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HAT6798092.1"
                     /translation="MLKDKTVVIGISGGIAAYKACDVVSKLKKLNANIHVIMTKSATE
                     FVKPLAFQSLSQNYVVEDMFEEPKTWEVEHISLAKKADLFLIVPASANVIGKIANGIA
                     DDMLTTTVMATKAQVLIAPAMNTNMYENPIVQKNIQTLKSFGYKFIEPESGRLACGDI
                     GTGKLANPDIIVEEVLTNLTKEQDLKGQSMIVTAGPTVESIDPVRYLTNRSSGKMGYS
                     IAREAIARGADVTLISGPTNLSIPQNLKKFVQIESAQDLYEAVVSNLSENKIVIQSAA
                     VADYKPKTYSDKKIKKKNDDLSIELSRNYDIAYEIGKIKEDKILIGFAAETNDLIEHA
                     KGKIKKKNLDFIVANDLTKEGAGFRADTNIVKIIDVEGNITEYPKMKKEEVANVILDK
                     VKALLEK"
     gene            complement(29802..30068)
                     /locus_tag="JAM15_07505"
     CDS             complement(29802..30068)
                     /locus_tag="JAM15_07505"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HAT6798093.1"
                     /translation="MLKPSINEVLEKIDNRYYLVGTVSKRARKLIDGEEPYVSNKTKE
                     KPVCVATKEVASGKITYRLLTEEEIEIEEARHHAEQHQQISEEE"
     gene            complement(30071..30688)
                     /gene="gmk"
                     /locus_tag="JAM15_07510"
     CDS             complement(30071..30688)
                     /gene="gmk"
                     /locus_tag="JAM15_07510"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HAT6798094.1"
                     /translation="MFVKKGLLLVVSGPSGAGKGTICKELLKENDTIKLSVSATTRKP
                     RTGEVDGVNYFFISKEKFEEMIEKGEFLEYAQIYDNFYGTPKAAIMECLEKGQDVLLE
                     IEMQGAKQIKEVCPEGVFIFVLPPSLEELKNRIVGRGTETEAEIEKRFSCAYEEIKMI
                     KDYDYFIFNEDVKTSAKEIEGIISSEKNKVSRYKNIIIEKFKEEL"
     gene            complement(30718..31599)
                     /locus_tag="JAM15_07515"
     CDS             complement(30718..31599)
                     /locus_tag="JAM15_07515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HAT6798095.1"
                     /translation="MAISMTGFGRGEYKDDNYYFLVECKTINHKYSDINIRLPRKISF
                     LEDKVRNLVKNYVKRGRVDLYIKFDLLGKEDVNLNFDEGLASQYIDILKEIKNKFDII
                     DDISVMNVAKFPDIVKIEEKEEDEDLLWSMLNQAVEDALIKLREMRSEEGKKLAEDIA
                     MRCDLLKNHIEEIEKYSSSVVEDYREKLNLRISELLDDPSIIDENRLAQEVAIYADKS
                     SITEEIVRFKSHIGQLKNTIFKDDSIGRKIDFLIQEMNRETNTIGSKSSDINITNLVV
                     EVKSELEKIREQIQNIE"
     gene            complement(31603..32433)
                     /locus_tag="JAM15_07520"
     CDS             complement(31603..32433)
                     /locus_tag="JAM15_07520"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HAT6798096.1"
                     /translation="MKFWKLHGIGNDFIAIDGRFDQINPSDYTALAKKVCHRRFSVGA
                     DGLLVVKDSKVADVEMVYYNSDGSRAAMCGNGLRCFCKFVYDNCIVKKESFTVDTLDG
                     IKDIKINLTNREINSIRVNMGKGSFIAKDVPVLTNKERFVQESIKVLDRELKVTSMLM
                     GVPHTVVIVDELDVDDVCKYGKEIENNKIFPEKTNVNFVKVEDKYNIHVYTWERGCGY
                     TLGCGTGMTASAIVCNLLNMVESSVNVTSQGGTVKIDVGDFSYMTGPAVKICEGVLEV
                     "
     gene            complement(32720..33754)
                     /gene="ltaE"
                     /locus_tag="JAM15_07525"
     CDS             complement(32720..33754)
                     /gene="ltaE"
                     /locus_tag="JAM15_07525"
                     /EC_number="4.1.2.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low-specificity L-threonine aldolase"
                     /protein_id="HAT6798097.1"
                     /translation="MRFIDLRSDTVTMPTDEMREAMAKAPVGDSIFRDDPTVNKLEEL
                     AAAKVGKEDAIFLPSGTFGNQLALFTHCLRGQEIIIGKGYHIVTHEVGAPAVIAGVQL
                     RTIDEDESGALNPELVEKAIRRDDIHEPQTGLICVENAYSGGTVVSLDNLREIKKIAE
                     KHNLPVHLDGARLFNAALTLGVEAKEIAKCCDSVMFCVSKGLAAPMGSILAGSKEFIA
                     KARRKQKVMGGGMRQVGIVAAAGIIAIEKMTLRLNEDHENAKYLACELNKIDGIEVNN
                     VNPDISMVFFKMSEDIIKEDVLIKEFFERNIKINKMENGEYRFVTHVDITKEDLDYVL
                     KTLKELIGVC"
     gene            34050..35825
                     /locus_tag="JAM15_07530"
     CDS             34050..35825
                     /locus_tag="JAM15_07530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin/fibrinogen-binding protein"
                     /protein_id="HAT6798098.1"
                     /translation="MALDGLVIHSIVDELSSKLTGGKIDKIHQPEDDEVIFNIRNNKE
                     NFRLVLSASASNPRVYLTSNYQKENPLKAPMFCMLLRKYIQGGNIVEISQIGFERIIK
                     ISVESLDELKEKTVKNIMIEIMGRHSNIIITHGEENKIIDSIKRVPFSISRVRQVLPG
                     HDYSLPPEQNKLNPLDDISKDLFIKNLEELEGPIFKSIYSKFLGISPIIAKEICYRAG
                     VNQNAIIKDISDEQFDSLHKVFCNLFNDINSNKYSPCIIIDKKVDKVVDFSCINLTLF
                     SDLSYINKDSMSRILEDFYRTKDIKDRINQRSSDLKKSISVKLDRLYNKLKKQEEELS
                     ESENADIYKIKGELITSYIYMVEKGMESIEVANFYDENCNDVTIELNKNLTPSENAQK
                     YFKKYNKMKHAKVEISHQISLNKEEIDYLENIILSIENCENLAELQDIKEELAKVGYI
                     KTQKKNSKKDTIPSTKPHEFVSSDGFKILVGKNNKQNDYLTLRLADNDDLWMHTKNIP
                     GSHVIIKCAGKEVPDNTVFEGAMLAAFFSKSKLSSQVPVDYTKRKNVKKPSGSKPGMV
                     IYETNSTIYVTPEEETVAKLKVKSE"
     gene            complement(36040..37692)
                     /locus_tag="JAM15_07535"
     CDS             complement(36040..37692)
                     /locus_tag="JAM15_07535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAT6798099.1"
                     /translation="MLLVKVENLKKYYADKLILDIDKLEILENDKIGLVGSNGQGKTT
                     LLKAILGEIEIDEGYTYLTESYSYISQSENNIETCSHSKEKSLLNAPDKFEEYLSGGE
                     KVKLKIADALSNKKNIIIADEPTSNLDKKSIGLLEDMFKRHEGALLLISHDRRFLDEL
                     CTTILELEDGKLKAYKGNYTDYLMQKDEEVKRADFEYQEYVKEKKRLEKALLYKKALS
                     DGIRKTPKRMGNSEARLHKMGGQTNKKKLDSNVKAIKSRIDKLEVKNKPKVSKEMNIK
                     IQDGMEIISENLVEVKDMTLKLENKLLLDNVSFKIKRGKKIALLGDNGCGKSTLIKEI
                     LADKNDNIKINNKVKVGYFDQNQSLLDEEKSVLYNTKVNSSFDESFIRINLSLFGFKG
                     DDVYKKVKVLSGGEKVKIALCKIILEDNNFLVFDEPTNYLDIKSMEALEKALINTDKT
                     MLIVSHDRVFVSHICNYIIEIKDAKIREFDCNYDEYIISRNKKTPSRDKQIKKENLLV
                     LENRLTTVISMLSIEKDNLKKELYESEYNELLKQITKLKNSF"
     gene            complement(37991..39202)
                     /locus_tag="JAM15_07540"
     CDS             complement(37991..39202)
                     /locus_tag="JAM15_07540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HAT6798100.1"
                     /translation="MKKTIMSLQHLLAMFGATVLVPILTGFNPSVAIFCAGVGTLIFH
                     FCTEGKVPAFLGSSFAFIPVILAAKEAYGGDLAYAQGGIIVAGLIYIIMSIIVKIVGV
                     NKIKLYFPAQVTGAMIVVIGLNLLPTAFSMASANFVIAFITLAIAILTNKFGRGFIKQ
                     LGILIAVFSGYIICLILRLVDITTITEASLFAIPNFTVPKFSLGAIVIISPVVLAVFM
                     EHIGDMTTNGAVVGKNFIENPGLNRTLLGDGFATIVAGCLGGPANTTYGENTAVLAIT
                     KNYDPSILRRTAIFAILLACVGKFGGFLQSIPGSVMGGISIMLFSMITYVGLKTIRDS
                     SCVESKINILIIAVILLIGLGTTYLSNKGISVGIPITSTVKITGLSLAAIVGIVLNRI
                     LNNQDFKVEEE"
     gene            complement(39486..40019)
                     /gene="pyrR"
                     /locus_tag="JAM15_07545"
     CDS             complement(39486..40019)
                     /gene="pyrR"
                     /locus_tag="JAM15_07545"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HAT6798101.1"
                     /translation="MVEKAQLMDEKAIARAITRISHEIIERNKGVENLVLVGIKTRGV
                     PIANRISKKIEQIEGTKVDTGDIDITLYRDDLEKIHVEPVVKGTYLDFNVNDKTVVLV
                     DDVLYTGRTVRASLDAIIDIGRPKSIQLAVLVDRGHRELPIRADYVGKNVPTSRHEII
                     SVSLLEIDGEDSVTIKE"
     gene            complement(40378..41325)
                     /locus_tag="JAM15_07550"
     CDS             complement(40378..41325)
                     /locus_tag="JAM15_07550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAT6798102.1"
                     /translation="MFYFLKVKVGDIMDEVKEFLVLEEEEEVRLDIYLAEQLGDMSRS
                     YIQKIIKDGKVKVNNKVEKAKYLVKEEDNIVIEIPEPKVLEVLPQDIPIDIVYEDDDV
                     LIINKPQDMVVHPAPGNYENTLVNGILYHCKDKLSSINGVIRPGIVHRIDKDTSGLLM
                     IAKNNYAHNFLAEQLKEHTITREYEFICYGVVKEDKITVNKPIGRNPKDRLKMAVVKD
                     GKNAITHFEVVERFDKFTHMRARLETGRTHQIRVHALSINHPLLGDFVYGPKETKFKL
                     KGQTLHAKKLGFIHPTTKEYIEFNSELPEYFKEAIKKIK"
     gene            complement(41294..41740)
                     /gene="lspA"
                     /locus_tag="JAM15_07555"
     CDS             complement(41294..41740)
                     /gene="lspA"
                     /locus_tag="JAM15_07555"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HAT6798103.1"
                     /translation="MLYILIIILLIGLDQLSKIWVLNNLVDVSTIPIINNVFHLTYVE
                     NRGAAFGLLQNNQWIFIIVALLATVFGLYYLNTRKVHIFGRLGIILIISGALGNLIDR
                     VRLGFVVDYFDFRVIWEYVFNVADVFVVVGTVFLCIYVLFFESKSR"
     gene            complement(42050..42829)
                     /locus_tag="JAM15_07560"
     CDS             complement(42050..42829)
                     /locus_tag="JAM15_07560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HAT6798104.1"
                     /translation="MKKAIWGICICLLSIVGVYTYNHNTHNQNSSKETYTLNDNIKDD
                     YEDVIIKKGNEDEKILALTFDDGPDEDFTPQILDILKKNNVKATFFVVGEKVEYNKEL
                     LKRQYDEGHEIGNHTFTHINVAKNSYGSVEKEITDTQNIIKSVIGVEPKIFRPPYRAM
                     SKSVCDIIVSKGMNIILWSNLDPRDWSNPGVDTIINTILTKVQNGNIILLHDYNTKRN
                     DKSQTIQALEVVIPKLKERGYKFVTVSELIQHLDKNKQVQK"
     gene            complement(42879..43361)
                     /locus_tag="JAM15_07565"
     CDS             complement(42879..43361)
                     /locus_tag="JAM15_07565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAT6798105.1"
                     /translation="MDTKKYKDKLLKEREKLTNLVVDMKDNTLFGDTTKHTSEKYSSG
                     ELSSYDNHIGDMGTDLYMQNMQNSLINHEEGRLYQIDSALSKIENGTYGFCDLCHNQI
                     DLERLDILPDTNLCNNCAKKENALLGDAMQNPDVEDSNFYSEDLTNLTDLNKNGTLRD
                     "
     gene            complement(43545..44966)
                     /locus_tag="JAM15_07570"
     CDS             complement(43545..44966)
                     /locus_tag="JAM15_07570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HAT6798106.1"
                     /translation="MVSFLGSIVVLIVGYFIYGTFVEKVFGINDKNQTPAIACRDGVD
                     YVPMKWKRIFLIQFLNIAGLGPIFGAIQGALFGPSAFLWIVFGTIFAGGVHDFASGYL
                     SMKNKGTSASELVGLYLGNGAKIAMRIFSVILLVLVGVVFVTGPAGLLKTLTGVNAQI
                     WVGVIILYYIMATVLPIDKLIGKIYPLFGAALLIMAVGVAGGLIIKGYNIPNINLQNM
                     NPNGTPLFPYLFITIACGAISGFHATQSPLMARCVEKESEARPVFYGSMVAEGIIALV
                     WAAAAMSYFHGIPQLNVIFNDGGAATVVNTVSVGLMGPIGGALAILGVVACPITSGDT
                     AFRSARLTIADAMNYNQDAVKNRFLIALPLFAVGVALTFIDFNIIWRYFSWANQTLAM
                     IMLWTGSAYLVKANKNHYITTLPALFMTVVTFSYIMQAKEGFRLPVNISNGIGIVVAI
                     ILGLLFFKKAKDIKEQNAHKLAS"
     gene            complement(45112..45882)
                     /locus_tag="JAM15_07575"
     CDS             complement(45112..45882)
                     /locus_tag="JAM15_07575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6798107.1"
                     /translation="MRAIIVEDEFPARKELRYFIENKSSIEVVNEFTNGIEVLDFIQE
                     NKIDVIFLDINIPHLDGMLLAKTLNQFKSRPKIVFITAYENYAVDAFSLDVFDYVLKP
                     YSEERIISMLNKLEKSEMSDIELSNSNSNLYKYKKETVNQEIEEITHKISLWKGDKLV
                     VIDIDDIYYCEANERQTFIYTEKEKFILKEGISEVENLINDKTFFRTHRSYIVNLTKV
                     KEIIPWFNNTYILKLKNSDYEVTVSRSKVKEFRLLMHI"
     gene            complement(45887..47089)
                     /locus_tag="JAM15_07580"
     CDS             complement(45887..47089)
                     /locus_tag="JAM15_07580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAT6798108.1"
                     /translation="MKTSILIALIEKTSLIVVLFLLITKLKIFKQIFQKEEYSFNDLV
                     CIALVFTFLGIFGTYSGINYMGSIVNTRIISIVSGGILFGPMVGITAGVFSGIHRYFM
                     DIGGITSVPCLLSSILAGVLSGFLYKRIPKQHRVMYGILVGMISESFTILLIYLISYP
                     HSLAIQIIVGIYLPLIVGQIGIGFVISIVEGIEKDKKDIEARNKAEIKALQRQINPHF
                     LFNSLNTIASFIRFSPDKARELIINLSTYLRYNLEYSDNLIDINKEIEQVKSFVEIEK
                     ARFGELLTVSYDIEDVNIKIPSLIIQPLVENAIIHGILESGRAGVVKISIKKLPYSLE
                     NTVRISIEDNGIGISEEIINNVYQDNMPENKIGLYNVHLRLKLMYGRGLNIRRTDNGT
                     LIVFYVKE"
BASE COUNT        15924 a         8174 c         5170 g        18447 t
ORIGIN      
        1 ctattgcaaa tttttgttat ttatgataat ataaatatgt ttttagtctt taaatagtta
       61 tcattttaag gaggtgtgcg tagatggcaa aagtatgtag cgtatgtggt aaaggtaagg
      121 tttctggaaa ccaagtatca cactcaaata aacataataa aagaacatgg tcagctaact
      181 taagaagcgt aagagcgatt atagatggag ctcctaagag agtaaaagtt tgtactagat
      241 gtttacgttc tggtaaaatt gaaagagctt agtaactacg tttaaaagcc tacttccgta
      301 agtaggcttt ttaatttaat catttttact ctttctcata aattttagga ttatacttga
      361 aatccatttt ggtaatttta ttgttactac tttcatcaat actcacccca cactttatag
      421 ttaaaactat tttaacaaaa aaataataat gctccacatc caataagtat taatgcggta
      481 agtgctgacc aaatccagcc aggaagcaac attgacagaa ttacagccat tcctgttgct
      541 agacaaagta ttcctagcaa taccttagac ttgttatttc tcatggaaca cctccacata
      601 gaacctgtat ctataaatat tttcatattc aagtttatgc gacagttttc cattttagac
      661 caataaacac attatgtaat tttaattttt catactagaa ttattactga actccgatat
      721 agattctaca atatccaaaa ttcctttttt tctacttaac ctttcaggtc cactatataa
      781 aaccactggt ataactttag gaagtttaaa atttttatct tctatttctt caaggctttt
      841 tttcataata aaacttttcc aaatttgttc tctatacgat ttcaatcttg ggacaatttc
      901 agtatccatt tctgtttgaa attctaacac tatataatgt gatactttgc cacttttaga
      961 aaatacctta taaattatat caacttcttt tcctttatat tcacatataa aagatgtttc
     1021 taactctata tttttaagag ttaattcttt tgctattgag acacttgtaa aattttgaat
     1081 caaacttaaa aaactttctt tatctgaata cattcttctg tactcttctc gtttttcatt
     1141 gcttcttttt aaattcatac agttcctcct aggctataga ccttctatat tttagtaaag
     1201 atagtctata aattttattt tttaattttc attagtgagt attgacagtt gtgtgtaaaa
     1261 tatccagtaa agatattttt ttatattttt attaaaagat ataaattttt atattttaat
     1321 atattgacat ttacgttgcg taaaagtgta tatttaattt ataggaggta ttacttatgg
     1381 aatatacagt tcaaaaatta agtaaactag ctggtataag tactagaaca cttagatatt
     1441 atgatgaaat aggtcttctt aagccactta aaataaattc ttcaggttat cgtatatatg
     1501 gtcaaaatga agttaataaa cttcaacaaa tactttttta tagagaatta ggaattaact
     1561 tagaaaatat aaaaaacatt ataaattcac caaacttcga tagtttaagt gcgttaaaag
     1621 aacaccataa taaattgcta gccaaaagaa agcaaattga tttactaata gaaaatgtaa
     1681 ctaaaactat agctctgaag gagggaaaat acactatgac agatatagaa aaatttgaag
     1741 gttttaaaga aaagatgatt gatgaaaatg aaaaaaatta tggaactgaa attagagaga
     1801 aatatggtaa agatattata gatacatcaa ataaaaagct taaaaatatg tctaagcaag
     1861 attatgaaaa ttggcaaaac ctaaatatcg aaataattag taaacttaaa aaagctttta
     1921 aaactggtga tgcctctagt gaactggctc aggaagttgc aaaattacat cataaatggt
     1981 tgagttacac ttggaacaca tactctaaag aagctcattc ctctctagca cagatgtatg
     2041 tatatgatga acgttttaca tcatattatg atagagaaca acctggatta gctaagtttt
     2101 taagggatgc tatagtaata tatacaagag ataaataata taaaataata aaggtggtgt
     2161 ctcaaaatga actttttagt tcatgagaca ctcttttttg tatgaaatca aatatatttt
     2221 tatcatttta tcaatgaaaa acaggtttct ctctctattt tgagacagaa tctttattgt
     2281 ataataatta taatcaatac aaaataataa caaattatac aaaacttact tatactattt
     2341 atgctaaaaa caaaaaatat tttattaaag tttttaaaac ttatgtaata taaaaatcta
     2401 tactatagac ttgattatgg aaagaaaatt atcaaaatta ttacaattag atatactatc
     2461 tctaatatca ttgtcatgaa ttatctttaa aaggatatca taaatggagt ttatttttat
     2521 ataatcatct ttatttatag ctaacatcat gattaattta acagtagaat cttcactcca
     2581 atatattggt tcattcaata tggaaataca aatcttagtt cttatagagc ttaattccat
     2641 aggatgaggt atagctaaaa aatcatctat attggtagaa gataaacttt ctctgtaaaa
     2701 tacagattca gcaaatgatg gaaatacaat ttcactttga gttaatttgt tgcacatcaa
     2761 ctttataagc tcatctttat ctttgatttt aggattaaca ataaataaat ttttatcaaa
     2821 gaaattgtcc aaaagattac tataaatatg ggaattatta gtgattgact tagatatatt
     2881 ctctatatct ttttttaata gttttaaatc cactaataca ataggaatac tatcatgatt
     2941 taaaggaatt gtcgatatta ttatatctac atctgacaat tcactagcta aaaattgatt
     3001 aaatgataga cattgaagta tatttatttt atcatgaaaa actttgttta attgaacctc
     3061 taataaccta cttgaaccat accctgaacc acatactaat actacgtttt tacacttaat
     3121 attattttga aaaaatctct ctattccagc acctatatgc agggatacat atccaatttc
     3181 atcttctgtt aaagagtaaa tactattttt aaaaactttt tctatagcat ttaaagttat
     3241 ttcaaatgct aaaggataat tactctttat tgtatttata aggggattca ccttatttaa
     3301 attataagat ttagaattga gaattgattt aaagtgcagt actaaatcat caaataatac
     3361 actatcattt ctaaggtcaa aagtatattg attgttgatt acttctaaaa tttcttcaac
     3421 atactctata attttagtat ccaccctatt ggaaacgtta tccaaaagag aacttttggt
     3481 tataaaatga ttatatagat aaactctgtc tgcctttgaa ataattatag tatatttact
     3541 ctcaatataa ttaaatatat tttcaacagt tgtattcgat tgaaaatctg ttaaaacaac
     3601 atctaaaaca ttatctaagc agtaaccatc aagtattcta cttatagtaa tagctaaatg
     3661 gataataaag ttttttagat taaaatctag aaaattgata ttaaatttat taatttcact
     3721 taacactacc ctttgaagct ctattaaatc tacattatta aataattcta tttctctatc
     3781 tgtaattcca attatatagt tttcaaaatt cctatttatc atattattag aaatacatct
     3841 tcgaatatct atttccttcc cttcaacttt aactccataa tatggcttag aaactaatat
     3901 taaattatac tttgacaaaa taggctttat tctttttatg tcatttagta ttgtaaattt
     3961 actcacatac aagctattag ctaaatcttc tagttttata tatgtattgt tatagagaat
     4021 atattttaaa atatattgat ttctttctat aggagaatct ggtatttcac ttgaatccat
     4081 aatatcatca gatattaatg ctagatactg ttggtataat gctaaattaa gaatatctat
     4141 ataatatcct tctccttttt ttattttaat aatagcacca tttttctcta aagttccatt
     4201 tatagaagta atatcatttc ttatagttct ctcactcact tttaaatgac tacttaaagt
     4261 tttacaagta attttatcat cactttcatt taataattta aacaacgtga gcaatctctt
     4321 gtgcataaat atcccccctt atagaatttc ttctaaatta tactatttac actcatataa
     4381 tacaattact ctaataaaat tgtattataa taatttattt ccacttctat atggaaatta
     4441 gttattatca taatataaat ttccatgtcg aagtggaaat tagttatatt taatttaatt
     4501 aggataatga ttacaatata aatataagtt aagacattac gaatggagtg gaaaaatata
     4561 tggtactaca agaaaaatat atatttatag ataaagactt aaaaagcaaa gaagaagtat
     4621 taaattttat tgcagatagt gcttatatac taggtattac aactaataaa gaggctcttt
     4681 taaaagacct tctaaaaaga gaaaatgaat ttccaacagg aataaaagat ggatttgcga
     4741 tacctcatac aaaaagtgta aatgtaaagg aagcttccat actctatatt aaaacaacta
     4801 acgagttaga gtggaaaact ttagatgata gtaaggttag atatgtattt agtttgttag
     4861 ccccacataa aaatgaagga aatatacatt tgaaaactct atctaaatta gccacatgtt
     4921 taatggagga tgattttaca agtgaagtta aaaatgctag tgatgcaagt catttagtaa
     4981 aatatataac taataaaatg aaggaggaat aattatgaaa atagtagcaa taacatcatg
     5041 tatagcagga ttagcacaca cacctatggc agcaaaagct ttagaacaag ctgcatcaaa
     5101 aatgggtcat gaaatcaaag tagaacaaca aggtgctatg ggacgagtaa atactataac
     5161 aaaagaagaa gcacaagatg cggactttat acttatagca tctgaccaaa ctatatctgg
     5221 aatggaaaga tttgatggta aaaaagtgat aaaagtcaaa ataggtatag cgttaaaaaa
     5281 accagaagct gtcttaacaa agtgtataga agctatttct taataaaaaa atctcactct
     5341 aatatagaat gagaaaaata aaaaattaaa aaattgtcta atgtaattat aacatattat
     5401 caaaaaatat aacaaactta tataggagga ttaaaaatga gtaaaaaaaa taaatctctt
     5461 ttaagtgaac ttaagggaca cttaatgaca ggtatctcat atatgttgcc acttgtaata
     5521 ggctcatctt tagttgtagc tatcccaaag cttacagctt tagcaatggg tataacaagt
     5581 ttagatgctt ataaaaatgt atctggtttt tatcatattc tttacttaat ggaacaagtt
     5641 ggttggactg gcataggtct attaaatacg gtattagcag gatttatagc attttcaata
     5701 ggtgagaaac cagctatggg tgcaggtttt attggtgggc tcatagcaag taatactaat
     5761 gcaggattct taggagcagt aatagcaggt ttctttgctg ggtatgtttg taagttttta
     5821 aagaaaaaaa ttaaaatatc tgggtcagca tcaggaatga tgccacttat aataatgcca
     5881 cttataacag ttggattaac tggtttttta atgagtgttg tattagcagg acctttagga
     5941 aacataaata cttcattaaa tgcttgggta gctgaaatgt gtcaaaatgg aacaaattcg
     6001 gtggtattgg ctttaatttt aggcgcaatg ataggattcg atttaggtgg accagtaaat
     6061 aaagcagctt ggatggcagg aaatgcatta ttgttagagg gaatctatct accagcgata
     6121 ttggtaaact gcgcaatagt tatacctcca ctaggatatg gtttagctaa attcataaga
     6181 aaatcaaaat tttccaatgc attagctgaa acaggaaaag gcaatatagt tatgggtata
     6241 attggaataa cagaaggtgc aattcctttc actttaacaa atccattaaa attagttcct
     6301 gttaatatga taggatgcgc tttgggtgta ggattatcag ctttgttagg tgtacatgct
     6361 ataatgcctc cagttggtgg attatatgga tttatatcaa taggttctgg atgggcttac
     6421 ttagtaggtg caatatttgg agctttagta atagcaatat tatcaacaac tttagtagac
     6481 ttcaatgaag atgaaactac ggaaaataca gaatttgatg aaatagagtt agatataatg
     6541 taaattaaaa acttaatttt agataattga gaattgagtg tactctcaat tctcaattaa
     6601 attttgggag gatttttatg aaaaagacaa aagtacatgt agttccacac agtcattggg
     6661 atagagaatg gtattttaca acatcaaggt caaaaatata tttaatgaaa gattttcaag
     6721 atatattaga catattggaa gaaaaagagg actttaaata ctttactatg gatgcacaag
     6781 cttctctctt agatgattat ttaaaatgga gacctcagga tgaatataga ataagagatt
     6841 tagttcaaag aagaagatta gttattggac cttggtatac tcaaacagac caattggtta
     6901 tatcaggaga atctataatt agaaaccttt actatggaat agatagatgc aatgaatttg
     6961 gtgaacctat gagggttgga tatgtaccag attcttttgg gcaatcagct caaatgccac
     7021 aaatatacag aggttttgga atagatagtt cattattttg gcgtggagtt tctgatgata
     7081 tggtagatac aacagagttt atatggaaag gttctgatgg ttcaaaagta ttagcagttc
     7141 aaataccatt tggttattac tatggaggta atataccaga agatgattca gatttaaaag
     7201 aatatttaaa agatataatt ggaaaactta aggttaaagc ttctactaat aacgtatatt
     7261 ttccaaatgg atttgaccaa gcaccaataa gaaaaaacct tcctgatata ttaaaaaaag
     7321 ctaatgaaat agataatgaa aatgaatacg aaataagtaa tatagaaaac tatatagatt
     7381 cagtaaaaaa tgaaagaaat gaatttacag agcttaaagg tgaattttta aatgctaaac
     7441 atatgagaat acacaaatcc atattctcct caaggtcaga ccttaaaata atgaataaca
     7501 aattagaaaa ttatatcaca aatgtacttg aaccattatt aacattaagt tattcacttg
     7561 gaaatgaata ccctcatcta gttataaaag atatatggaa acttatgttt gaaaatgcag
     7621 ctcatgacag cataggttct tgtaatagtg acacaacaaa tgaggatgta tacacaagat
     7681 acaaacaagc cagagatttg agtataaatt tattagattt gcatatgaga cttataagta
     7741 ctcaaatcaa aaataataat gaagaaataa cattaacagt attcaatgga ttcccagaag
     7801 tcagaaatga agttatagaa tttgatactt atattccagg tcaagatttt gtgataaaga
     7861 ataaaaatgg agaaattctt aattatataa taaaagaaaa agaagatatt acaaattata
     7921 tattaactca aacaataaga ttaaacccaa gtaaaaaaat atatataccc aaaactgtat
     7981 atagagcaaa aattgcactt tcagtaaaag atataccacc aatgggatat actcaactag
     8041 tttttgaatt ggatactaaa aataaatgtg aaatagaaac aagtaattgc aaagaaatag
     8101 aaaacaaata ttacaaaata acagccaata aaaatggttc attagaaata ttagataaag
     8161 aatctagtaa gacttataaa aaccaagctg taattgaaga caatggagat gatggagatt
     8221 catacaacta ttctcctcca agaaaagata tttatgtttc atctttagat tctgtatctt
     8281 cagtagaagt actaaaatca aatattcaag aagaaatgat acttaaatat tcattgacca
     8341 taccagcttc actggaagaa aggtctatag gtaaagtttc tgtgaaaatg ccagtaacaa
     8401 tgaaaattac cttagaacct aaagaacaaa taattaagtt taatgttaat ataaaaaata
     8461 accaagcact atctcataga gtaagagttt tatttaatac agaaatagca tctaagtttt
     8521 ctatagcaga tcaacaattt ggaataatac aaagaccaac agtattagaa aaagaccttg
     8581 cattatggaa aagagacaat tactcatggc aagaaaaacc tataactatc gaaccaatgc
     8641 aaagttttgt tactttagag gatggacaaa gaggaatagc attaataact ggttgtgtaa
     8701 gagaatatca aatagttggt gataatttag atacaatagc attaacacta ttcaggtcat
     8761 ttggatatat gggaagagaa aatttacttt atagaccagg aagagcttct ggagaaaaaa
     8821 taatagcaac accagatgca caattactta aagagttaaa ctttgacttt ggtctttaca
     8881 tatataacaa taaatttgat gaagcaaatg tagctaatac agctaagaga ttcttaacac
     8941 ctatacaaat atatgaatat gctgattttt taaatggtag acttatattt gcattcaatg
     9001 acgaaaaaca aatatatgaa aatgaattta gtttgatgaa tgtaaataat tcaaatttca
     9061 cagtaagtgc aataaagaaa gaagaaaaag gagatggaat tgtagttaga atcttcaatg
     9121 gtatgaaaaa tgaggatgct aagggaagtc ttaacatcaa taaaaatgtc aatgatgctt
     9181 atagtgcaat gctcgacgaa atctatgata ataatagcaa gcttaaagta aatactaaaa
     9241 ctgtagaggt aaattcttta tcacattgta aagtacaaac aatagtaatt aaataatata
     9301 aaatagctta tacaagattt caaaataaat tgctagtact atgttaatag taaacccaga
     9361 tattatgcta tttataagct ctgtaacact aaataacatt ttgtaaaata aaaaggtgaa
     9421 ccttgtatat taggattcac cttttttaaa taaatcaaca ttctgtttta aaataacatt
     9481 tataagctgt tttgaaataa tacttacaaa ttattttaaa acaataccta taaattttta
     9541 tttaaagaat acacataaat atttccagac tcttttattc tatagacttt ataattatta
     9601 aagaagtcta atctaatttt tgttaaaagt aattgtaact ttaaataaat caccatccac
     9661 acttatattc atcttaccac cctgtaattc tataaaactt tttgctattg ctaaaccaag
     9721 accagaacct tctgtgttac gtgatttatc tcctcttaca aatctctcca ttatatcatc
     9781 tacactaaaa tcaatctcag atgcagacat atttttaagc ataatattta ctttattatc
     9841 tgtttctaaa atatcaatat acactcttga atttggcatt gcatatttgc ttatatttat
     9901 tataagattt tcaaatactc taaatgtacg ctgactatct aatggtaata ttattttttc
     9961 attagaaaag ttattcttta ctattagaga tgaatctgca agtttgtcat ctaattctaa
    10021 aagtgtctgc ttcattagag atacaatatc cacatttact atattcaaat aaacatctcc
    10081 actatttgcc ttgcttactt caaacaaatc ttctattaga tgttgcaatc tttgtgactt
    10141 tctgtctaat gtatcaatat acaacttacg attttcatct gttatacttt catcttttaa
    10201 taaatctata taagtgatta tagatgttag aggtgttttt aagtcatgtg atacatttga
    10261 tataagctct gttttcatct tttgactctt aacctcttcg tcaacagctt ttttaaatcc
    10321 agtttgaata tttcctaatt cgtcttttat aggattaaaa aatcctaaat ctttttccat
    10381 atttacatct aagtttccat ctgaaatttt ctttgtaaca tctaaaagtt gattatattc
    10441 atatattgtc tttttagagt aatctgacag tatcttaaat aatactactg aatatattaa
    10501 tgcgagtatt attccaaaga accacatact acacattata actataatca ataaatttat
    10561 tcccaaaatt gtaactatag ttttatttgg cttttctttt agatttattg ttctaatttg
    10621 attaataact gtttttcctg ctttttttaa ccatacaaaa aacattcctg tcacagtatg
    10681 ttttgtaaaa tactctctta ttccaacatt taaaatatgt tttaaaagta ttataaatac
    10741 aaatattatt gagaatatta caaaccaata agttaaattc attaaactta ccaatatgct
    10801 agccatttta gcacttatgt cattgtttat aaggtactct acataattcc cactcaaggt
    10861 attacttatt ataacagtag gatataaatc tacaagcccc tgtataatag caagagcaat
    10921 aaagagtatc tctaacggta ttcttaataa tgtatcaaat cctagcaact ctttagattt
    10981 tctatatggg aatgctaaag ctacaataac aactatagct aatataattt ttaaaatcat
    11041 tccagaaatc ttataataag aattattttc tacattgctt atatatgaaa ttataccatc
    11101 atcaaaataa gtatttccat aaccatactc tacactatca cctttactta ttactttagg
    11161 tacagcatat actaatgtta tattttttat tggagataac ttatatgaaa ttgaatttcc
    11221 tcctaaactt gtatccatta aatcttctct tgctttagat aacaacattt gattaataac
    11281 tttttgattt actccataag aatccacaat atttactttt ccatctttat caaaattcat
    11341 tacaacgtag aatctatagt tttcctttat atctgtaatc tgcttttgtc tttcctcatc
    11401 attcatttct gtattttttg actgattttc atcagaattt tcttttgaag catcattctt
    11461 tgttgtatca agtactccta attctttatt atcattaaaa aattcaaaat tgctttcttt
    11521 atcaactaaa tagtacttta aattctttcc tgacgcttta atgaaatgct cccaattttc
    11581 aaagttttca ttaaaatctg cattaatact atcatctgta taataagttt ctgaaccatc
    11641 ataagtatct ttttctttac ttacattttt tatatagttc atagtttctt cattgataaa
    11701 tagctttgat ggttgtatca tcttaccttc ttgttcttcc ttcatattat gatataaaac
    11761 ataacttcct ttatatatac tatctacaaa gctttcctgt tcaaatggat tctttgctcc
    11821 acctttagca cctgcttgta tagtagaata ttgactaatc atacctaatg atgctgatag
    11881 cataagtata aaaactataa tagtaactat atatttatct ttaaattttt tcaattttgt
    11941 atccaacacc ccacaccacc tttaaatatt taggattttt tgggtcaatt tctatctttt
    12001 cccttatatt cctcacatgt accataactg tatctgtatt tacagcattt tcattccaaa
    12061 ctctttcata tatttcatca gcagaaaaaa ctcttcctgc atttctcata agtaaactta
    12121 gtattttaaa ttctatagga gttgttttta tatattttcc atcaatatta acttcttttg
    12181 tattttcatt taattctaat ccgcctattg caaacacact atcatcactt tctacctttt
    12241 gctctttatt tccaaccatg tttagatact tagtgtacct tctaagttgt gaattaactc
    12301 tagccaatag ttctaatggc ttaaaaggtt ttgttacata atcgtctgct cctatattaa
    12361 gccccattat tttgtcaact tcttctgatt ttgcagatag cattattact ggaaaattat
    12421 agttttctct aagcttcatt gtaagtgtta taccatccat tttaggcatc attatatcaa
    12481 ctatagctaa atgtatttct tggttttcta taaccttaag accttctaat ccattgtatc
    12541 ccttaaaaac attatatcct tgatttaata gatatatctc tatagcatct gctatctcct
    12601 tttcatcttc taccaccaaa atattatatg aattcatttt aatctccttt atattaattt
    12661 ataaattttc tttacatata tgattataca atatgataga agtttttcca tttatatata
    12721 tatttatatc ttttgttctg gttatttgta tttaatgtcc atcttagaaa cctccttcta
    12781 gtttaaactt aatatttttt cattttgttt tatatactta atattaaaat taaaaactta
    12841 agatattaca tatacttttc taaagatttt ctaaagattt aaatatattt aaaattaata
    12901 tacaaaaaaa agtagttctt attgtattaa ttaaatcaat gatttgaaat ataaaattaa
    12961 tatcaataaa acctactttt taatttttta aatatttatt tttaatttat cttgttttta
    13021 atttactttg attttaaaat gtccttgact tttattttat aaatgtacat atttcttcta
    13081 ctggtttttt agatggactc ttcaaattgt cctctggcac tccaagagct aacattgcac
    13141 ctaaaaaata ctctcccttt tcaaaaccag tttctgcttc taaaacagct tctatctcat
    13201 ctgctgcata gttttgactt gtcaaccaac aagaaccata tccaagttca attgctgata
    13261 gtgtaaagtt ttcaattgca gcacctagac tctgcatacc tggatttctt ataaataatt
    13321 tatctatagt ctccttaggt gcatctataa gctctaattc ataatatcct gatgggttat
    13381 atacttttgt aaaaactaat actaaaactg gagcttttaa gtaaaatagt gtaaagtttt
    13441 taacaaattt tctaaatcta ttagccttat ccactgatac tttatccatt tccacaagta
    13501 tttcttgttg ctttttagtt atcacatctg ctatcttttc cattaaatca cggcgtttta
    13561 taacaacaaa atgccagttt tgaatattct tgcctgatgg tgctgcacct gctgctttta
    13621 tcatttttaa aatatcttca tctgatacat cttgattttt aaactttctt acactttgtc
    13681 ttttaaaaat agtatcttgt aattccattt ttaaatcccc ccataacttt tttattattt
    13741 taatataatt tttaaactca tcttatttta atatatcatg ttctaacaaa tctttaaatg
    13801 aatctataaa ataatcatat acatctacat tcccaaaccc atatttggca tatataaaag
    13861 gtatacctac aaacttagca ctatttgcat caccttgcgt atcaccaaca tagattggat
    13921 ttattaattt atttctttca attataagtt tattattttc tcctttatgc aaaccagtat
    13981 taccaggaca ttcaaaatct ataaaatact gttctagttt atgtgctttt aaaaaagatt
    14041 ctatatatcc agcttgacaa ttacttacta taaataattt atatttttta gatagtaatt
    14101 taagagtatc ttctatatca tcaaataatt tagctccatt ttcagataaa tagtcacatt
    14161 ctttcaaaga acattcattc aataaattca ttctttcttc ttcacttaaa tttggaaata
    14221 aacgatttgc tatttcctca aaagaaagcc ccataagact tctaaataaa tcttttgtga
    14281 cacttaattc tatttcctta tgtttactta aaacatcctg ccagactttg catacttctt
    14341 cagttgaatc ccacaatgtt ccatctaaat caaaaataat actatctacc acaaaaaatc
    14401 ccccttatgt caaagtttat tatatattta taattatata ctaaaaagca gatacaatca
    14461 taaatatatt ttacttgatt gtatctgctc tacaatataa aaccaattgt caaaatcaaa
    14521 ttttataaat ttctaactac aagtacacag ccttgctcta ctttaatctt acaagaatta
    14581 ctcaacataa catttgatat tccaataggt acagagtatt tcatataata attatcgaga
    14641 gggtattcta agccagtaag tgttacaccc ttagcatcac catttatagc tattacagaa
    14701 atagtgtccc ctgggtttcc atacaatgaa atttcctcat tttcaactat atacatctct
    14761 tctttatcag aaagtatcct agaatatata ccatcttctt ttaaataata taatagcttt
    14821 atatttgcaa gagtgtggtc aatccttccc cctaaagcac caaaaaaatc aatatgattt
    14881 gctttaagtg tcttagctaa aaaaagacaa agctctgtat cagtctcatc ttttttagat
    14941 ggaaattttt caaatttaac acctttattt ttatagaagt ttatcttttc ttcttctact
    15001 gaatctaaat ctcctaatat ataatctggc attatttcca ttttataagt gtgatttgcc
    15061 cctccatctg cacatattat gcagtcataa cattccttaa ttataatatc tcttgtaact
    15121 tcgtaatctt caatttcgcc atttaaaaca atacagattt tcattattaa atttaaacta
    15181 attcttcaag agaagcattc tttctaaata aattaactgt ttcttgaatg tcatcacttc
    15241 caaatattgc agaacctgct actattacat tagctcctgc ttgtacaact tcggctacgt
    15301 ttttagggct tataccacca tcaacttcta tatcaatgtt taatccttga ctatctataa
    15361 tagcttttaa ctctttaatc ttatctaaaa cacaaggaat aaatgattgt cctccaaatc
    15421 cagggttaac agacattaat aataccatat ctaaatcagg tagtacatgt ttaatcgtat
    15481 ctactggtgt agctggatta agtactacac cagcttttat tccatgtgat tttatatttt
    15541 gtatagttct atgtagatga acacaagcct cctggtgaac agttattata tcacatcctg
    15601 cttttacaaa ttcttcaata tactggtctg gattttctat cataagatga gcatcaaata
    15661 ccatatttat attttctttc tttaaacttt tgactacaag tggtcctaat gtaatgtttg
    15721 gtacaaagtg tccatccatt acatcgatat gaagatattc acatcctgca ctttctactt
    15781 ttcttacatc ttctaataat tttgcaaaat ctgctgataa tattgatggt gctaatttaa
    15841 tcatttttct aatacctcct actattattt tgtcttattt catgtagcag ctgtatataa
    15901 ctatcatatc tttctttaga tatttctcca tttgtaacag cttcttttat agcacaatta
    15961 ggttcatttt catgaataca ctttgaacca aacttacaat cattaaattt atcaaattct
    16021 ataaaataat ctttaagttc aacttcctct atatcttcaa gtgcaaggga actaaaacct
    16081 ggtgtatctg caaccattcc accaaattcc aattttaaaa gttcagcgtg acgagtagta
    16141 tgttttcccc tttttatttt atcacttacc actcctgttt gaagtttaaa attttcatct
    16201 atttcattta ataagcttga ttttccaact ccagatggtc ctgcaaacac tactacattt
    16261 tcttttaatt cttcttttac tttatctata tttaacttag taatattgct tacaggaatg
    16321 actttatagc cactaagttc atatatattt ttaacagttt ctaatgtatc attatcatct
    16381 aaatctgctt ttgtaaggat tattacagtt tctaaatttt ctttttctgc caaaactata
    16441 aatctatcta aaagagataa gtttggttta ggatttttta ttgcgaatac tattaatgct
    16501 ttatctacat ttgcaatagg aggtcttata agttctgtat ctctactgtc gatttcttct
    16561 aagataccct ttttttcatc ttcatcaaca atgcttattt tgactctatc accaaccaaa
    16621 ggtgttattt tctgctttct aaatatccct ctagccttac attcatagat accattataa
    16681 gtatctacat aataaaatcc actaatcccc tttataattt ttccttctag catcaaatgc
    16741 ctccctttat aaaatttata taaacacata ctgtttatga gtagtatatc gtgttattct
    16801 ttcctatttt tatataatac cacatttttt ttaaataaca aatcctccgt ttggactaat
    16861 tacctgacca gtgataaaat ttgatttgtc tgatgccaag aaaatagcac aatttgctat
    16921 atcttctgga gttcctagcc tcattagagg ggtttcttcc acaagagcgt ctatatcttc
    16981 ctcattatat ccagataaca tgtcagtatt aatgacacct ggagctatgc tatttactct
    17041 aatatttgat ggtcctactt ctttagctaa tgcctttgtc atacctatta tacctgcttt
    17101 tgttatagaa taatgcactt cacaagacgc acctgatata ccccagattg aagatatatt
    17161 aattatattt cctttttttt ctgatatcat gtattttaaa gcaacttgcg aacaataaaa
    17221 gcttcctttt aaattaatat tcatcatatt atcccaatct tcatcggtta tatctgtaaa
    17281 caacttatct tgacttacac cagcattgtt tacaagtaca tccaatcctc caaattcttt
    17341 tatacaataa tctaccatat tctctacatc ttctctattt gaaatatcag ccttaaaaag
    17401 ttttacagaa aaattttttt catttaatat agtatacaac tctttagctt cattttctga
    17461 cttattaaaa tttactaata cattgtaacc ttcttttgca aaagctttag acatagcttt
    17521 accaatccct ctagctcctc ctgtaattaa aacggttttc ttcttcataa atacttttct
    17581 ccttatatta taaccaattc agtattttat acaaaacaaa ctgcccttta aagaaaatat
    17641 tttctataaa aggacagctc ttattttatt aatatttatt ctgttttacc aatgtttgcg
    17701 ccagttcctg gtgaagttcc tccattatct cctgagtttg agcctcctga actatctcca
    17761 ttgtctcctg agtttgaacc tcctgaactt cctccattat ctcctgagtt tgaacctcct
    17821 gaacttcctc cattatctcc tgagtttgag cctcctgagc ttcctccact atttcctgag
    17881 tttgaacctc ctgagttacc tccattattg cctgagtttc ctccactatt tcctgaattt
    17941 gaacttcctg aatttccacc actgttccct gagtttgaac caggttctgt tggtgtatta
    18001 ttctctggtg ttgttggttt tttatctggt actgttggag tctgtgtatt tgatttttct
    18061 gaacctttgc ttacatatag gtttacctca tcaccttcct gagctcttga tgagccagca
    18121 cctggactct gacttaaaac tgtaccttct ttatatattg agctatattc atacttaaca
    18181 gttcccactt ttaagttatt ttcttcaata agttgttttg cattactcaa agtaagtccc
    18241 accacattag gaacagatgc ctgacttgaa cctttactta cgacaacatt tatagtatca
    18301 ccctttttga catttgtact tccaccttca ggtgtctgtg atattataca attttcatca
    18361 acttcactat tatactcttc actttttaca ctcaggtata atccttcttt ttcaacagca
    18421 ctttgagctt cttctaatgt catatttaca agattaggaa cagtcaaaga tttattgcca
    18481 aaccctccag caaataaaaa cttatatgct aagaatactt gagcacacaa tatcagtatc
    18541 aaaacagccg caattacttt taatcttctt ctagattttg ggctttcctg ttttttcttc
    18601 tttttcttag ttctcttact tggagtactc ttaggtctct gattcttttt agctctcatt
    18661 atctcttcct cttcttcttc ttcatcttct tcataaaaat catcatagta atcttcatca
    18721 tcatccaaat cagctacttc aacaggctta accacttttt caggagctgg ttttgcaagt
    18781 gttggattta caactttatt aatttctttt tcatcaattt tcttagttgc aaaatcatca
    18841 tattctttta taaaatctaa atcaatattt ttttctatat actctatatc ttctatcaat
    18901 tcttcagcag tttgatatct atctgcgcta gatttttctg taagcttttt tattgtagtt
    18961 cttacacttt gaggaatcct aactttttct tctgatgtaa agtctatatc atcattaatg
    19021 tgttgaagtg ctatagaaat tggactatct cccctaaatg gaacttttcc tatcaacatt
    19081 tcatataaaa ctatacctag agaatacagg tcagcattat tagttacaaa tttaccttta
    19141 gcttgctctg gtgaaaaata atgcactgaa cctattatac taccaatatt agtcattgtt
    19201 gaatttgaaa cagctttggc tataccaaaa tcagccactt ttactactct tccttcattt
    19261 gatatgagaa tattatgagg ttttatatct ctatgtataa tccccttttt gtgcgctgca
    19321 ctaagtgcca tagctatttg ttttgttata tctaatgcag tatattcatc taatatacct
    19381 tcatcttgta taatctcttt tagattcttc ccatctacaa actccattac aatgtagtga
    19441 acttttccat cttcaccaac atcataaaca tttactatat ttggatgtga aagacttgct
    19501 actgcttctg cctctctttt aaactttgtt agaaattcat catcatctac aaattcaggt
    19561 ctaagtactt taagtgcaac agtcctgttt aataatctgt ctttagcctc atatacaaag
    19621 gccattcctc catcaccaat cttcctgatg atttcatatc gatttcctaa aattgtatct
    19681 cccacaatat caccgtccta attatacttt tatcactata accgaaacat tatctttacc
    19741 agaaacatca ttggccatac ttatcaattc ttcacttata ttactagttc tctcatattc
    19801 ataatctaat attaaatctc ttatatcttc atcatcaata aacccagtta atccatctgt
    19861 cgcaagaagt attatatcac tttttttgat ttctttctta aaaatatcta caacaaccat
    19921 atcatctgtt ccaattgctc tagttattct atttctctgt ggatgtcttc ttgcctcttc
    19981 ttctgtaatg acatgggcca tcataagttc ttcaaccacg gaatggtcta tagttatttt
    20041 atcaaatttt tcatctgtta acaaataaca tctgctatct ccaacatttg ccacatataa
    20101 gacattatta tacactatag ccgtaactaa tgtagttccc attccttcaa attctatatc
    20161 ttccatagat tttttgtgca caattgagtt tacattatta taagcctgtt ttaatatatc
    20221 atctatatag tctattttta cattatcatg ttgtaataag ttttccttta gaaaatcaat
    20281 tatattttct actgctaatt tactggcgac ttcacctttt ttatgtccac ccattccatc
    20341 agctatggca aatattccta ttggaccatg ttctgtatct ataacttctc cctcacaata
    20401 gtcttcattg ttttttctta tttttcctat atgggaggca caactataaa ccatacgact
    20461 tcctccttac aaattacttg tattttcttc tcaattgacc acaagctcca ctaatatcag
    20521 aacccataga catcctaact gtggcaggta tattgttctt ctccaaacta tccctaaatt
    20581 tataaataaa tgctttatct ggcttttcgt attctctttc ttcaacttta tttattggaa
    20641 ttaaatttac atgacatagc atacctttta ggagcttagc taatgccttt gcttcttttt
    20701 ctgagtcatt tactcctttt ataagagaat attcaaatgt aacccttcta tttgtctttt
    20761 ttatataata tctacatgca ttcaatattt cttcaataga ataagcattt gctacaggca
    20821 taatttttct tcgttcttca tcatatggtg aatgaagtga taaagctaaa tttatagcta
    20881 tttctaagtc tgccaactca tacattttag gtactattcc acaagttgaa agagttatat
    20941 gtctataccc tatattaaga ccattttttt cgttaattat ttttaagaat tgttttgtat
    21001 tttcaaagtt atcaagtggc tcaccactcc ccatcaatac aagatttgat accctcttac
    21061 cagtatcttc ttgaatttta ataacttggt ctaaaatttc ccatggctct aagtttctaa
    21121 ttaatccatc cattgtagat gcacaaaaat tacatcccat cctacaacct acttggttag
    21181 aaacacagac agtaactcta ctatcataat ccatcatcac agtttctatt atatttccat
    21241 catctaataa aaacaaatat ttttttgtat tatctacctt agattctaac tttaattcta
    21301 tatctatatt ccctatacat gaaacctctt ctaatttatt tctcaaactt tttggtatat
    21361 tgttcatatc atcaaaagtt tttgcaccct tatatatcca agagaatatt tgacttcctc
    21421 taaagggctt ttcatctata gttttcataa attctttaag ttcatcttca gtaaaatttt
    21481 ttaatactat ctttttcttt tccattctct cactacctta ttctctttaa ttttgctatg
    21541 aaaaaaccat ctataccatg aatattagga tatatcttta aatatccttt atcttgattg
    21601 tctaagtcta catttactgt atcaattgga acaaattcaa agttgtgatt ttcttcaaca
    21661 aaagaagtaa ctatatttat attctccaca tcttgaattg tacatgtact atatactaaa
    21721 gttccaccaa ctttgacata tttagatgca ttttctaaaa ttttcttttg tatagaagtg
    21781 atgtctttta actcttcttc tttcttatac ttaatttctg gtttacgtct tattatacca
    21841 aaaccagagc aaggaacatc tgctaaaaca taatcaaatt tacttatact attttcatca
    21901 atctcagaag catcaaatct ttctacaaac acatttttaa gccccaatct atttacagta
    21961 gagtttataa gctttagttt atgctcaaaa atatctctag ctactacttg accagtattg
    22021 ttcattaaag tagctaagtg agtagatttc cctccaggag cactacatac atccaaaaca
    22081 aatgaacctt cttttggatt aattactttc cctactatca tagaacttat atcttgaatt
    22141 gtaaataaac cagccttaaa taattcattt ttttctatat ttttcatttt ttcgacttta
    22201 atagcttctt ctaccatagg aacttttaaa catacaatac ccatttcact taatttttca
    22261 ataagttctt ctctacttat tttaagtgta ttcgttctta tatagatact aggcttttca
    22321 ttatttgctt ccaacaaatc ttcagcaaat tcttgtccaa atttatctat ccagtttttt
    22381 ataatccaag agttatagga atactttata gataagtatt ttacactatc ttcctcagtt
    22441 atgtccatta tagtctcttt agctcttatt tcatttctaa gaatagcatt tatgaaacca
    22501 gaagattttt tatcatattt cttagataat tttacagttt cattaactgc tgcataatct
    22561 gatatactat ctaaaaataa aatctgatat gttcccattc ttaaaaagat tttaacataa
    22621 gttgacattt tttttacctt tatttttgaa agtttattga ttatataatc taaataatat
    22681 ttattttcta ttactccata aattaactct gttgcaagtc ctctatccat atcacttatt
    22741 tctaaatttt taaaatgctt atttattgca atatttgaat aattgtcatt tttttctata
    22801 tcacataata ctttaaatcc aacttctctt gcatccatat aaatttctcc cttttattaa
    22861 acataaaaaa gggttgtttc taaacaaccc actttacttt tagtcatttc ttctttgagc
    22921 tattagtaac aatctaagta attgaagtat tgaaaccaat gctgctgcaa catatgttaa
    22981 agctgctgct gaaagtactc ttctactttg tcttgactca ctttcatcta taatacctaa
    23041 attcccaagt tgaacgattg ctctacttga agcattaaat tctacaggca atgttattat
    23101 ttggaataac actgaagccg aaaacaatag tataccaatt tttaaaaatg gaccagccat
    23161 aataaatcct aaaaatatta aaaaccaaga tatacttgaa gcaaaattca ctactggtac
    23221 taaactactt cttatttgaa gaggcgcata acctttagca tgttgtatgg catgaccaca
    23281 ctcatgtgca gctactgcaa cagaagttat agatgttcca taatatacat cttctgacaa
    23341 ccttacagcc tttcttcttg ggtcataatg gtcacttaga tgccctctaa ccatttctat
    23401 ctttacatca tacaaaccat ttgaatcaag tactcttctt gctgtttgct ctccagtata
    23461 tcctcgacgt gtatttactc ttaaatactt atttgttgtt gaactcactt taaattgtgc
    23521 atatatagta agtaatatag ctggaattaa tacaaccatt gttgggtcaa atccccaaaa
    23581 accgccatat acagggtaca taaataacac tctcctaaaa tatattttta ttatacatcc
    23641 tcttaatatt cacttaactt aaaaacagtt taattacaaa ttaatatatt ttttcctgtt
    23701 aaaaagccta tagctttttc aatatccatc atgtctacat tagtatttac acaaggtcca
    23761 ttaggtcttt tgttaaatac acctaaaaca ggaattttct taatatcttg tattccagat
    23821 gtcaaatctc tttcacatgc aacagctaca acagctttag gtttattatc cattataatt
    23881 tttctagcta gggttcctcc tgtagctaca aatattttta cattagtttt ttcctttagc
    23941 ttaattaatt ctcctacgtt gcatcttcca cattctttac aattatctat atcattagta
    24001 acttttaatt tacaactatt ctcttgaata caatgaggta ttaaaattat tatatcctct
    24061 ggattaaaat tatatttatt actgtatata tattcattat ttaactttat atatattctt
    24121 ctaatatcac tttttgacat accaaatgat gatgcaatga aagatataat aggaaataat
    24181 ccactgacaa tattaaaatt tattttcatt atatttgagt taacatactt tcctttaatt
    24241 actctataag taactgctgt tgaacatagt attataagta ttagtgatat tattataata
    24301 tttatcatca aggagaatat ttgagttaaa cttattataa aaaaattaac aactcctatc
    24361 aaaattccta atattaaaat caaaatccca acacttgtta aatacttctt tatatctgtc
    24421 atacttttca cctaacccaa tactaaacca gtttctatag tattcccttt tatatattca
    24481 ccaaccaaca ttctcttttt attcggcatc tgaatttctt caattaaaag tacattatct
    24541 atagtactta cttttatccc atctttgctt acatcaatta ttgtacctac atcttttgtg
    24601 cttttttcat ctaacacttt agttttccaa actttcatta tgacatcatt ataggtagta
    24661 taagcacttg gccatggatt tactcctcta actaaattgt gtatttctct ggcacttttt
    24721 gaaaaatcta tgttacctaa tgatttattc attattggcg cataggaaaa ttcttcatga
    24781 ttttgtactt ctcttggagc atttccttct tcaattaatc ttaatgtttc ttttaaagtt
    24841 tctgctccta tattcatcat tttatcatga agttctcctg ctgttatatt ttcatcaaga
    24901 tttacttctg tctttagtat catatctcca gtatctaacc cttcatccat atacatagtt
    24961 gtaacaccag tcttttcttc accatttatt attacccaat ttataggtgc cgcacctcta
    25021 tattttggaa gtaaagaaac atgaacattt atacatccaa gtttaggaat ctctaatatt
    25081 tcttttggaa gtatctgtcc aaaagctaca actactatta catctggatt taaagattta
    25141 attttatcta taaattcttt atctctagcc tttactggtt gatatacagg tatattattt
    25201 tcaattgcca gttcttttac tggactcata cctagttttt tacctcttcc ttttggttta
    25261 tctggttgag ttacaacacc caatatttca tacttctcat ctattatttt ttgtaaacat
    25321 ggaactgcta tatcaggagt tcccataaat actattttca tcaaatcaac tcctactact
    25381 tttctatttt gtcaacaaat aaaattccat ctaagtggtc tatctcatga caaaatgctc
    25441 tagctaaaag ttcttctccc tctaactcta ttgtttcacc atttctattt aaagctctga
    25501 cctttacata atttggtctt ctaacatttc cagcttctcc aacaacactt aaacatcctt
    25561 cctcatctat ttgctcccca gatgtttcta ttatttcagg atttataagt tctataagct
    25621 cttctccaat atctattact actactcttt ttaatattcc aacttgaggt gcagccagtc
    25681 caacaccatc tgcatcatac atagtttctg ccatatcatc taataattgt attatctttt
    25741 catcaatttt ttcaaccttt tttgattttt ttcttaatac tggttctcct atttgaacta
    25801 tttgtcttaa agccattata attcctccta aatttataat acactgtttg gattaatatc
    25861 tatagataca ttgatattct tatcaaatat caaatctcgt tttgttatac atatatattt
    25921 tattataccc tttaagagat taatttcaat attttcatct ttaaagagta tttgccatct
    25981 ataattttga tttatttttg atattgaaca tggatttgga cctaatataa atcctaaatc
    26041 atttataccc cttttttcta ataaataaat caatgatgca tgcatatttt ttatattttt
    26101 tatcactaat ctttcatctt caccactaac aactacactt aacatattat taaaaggaga
    26161 atatccaaat gcttttctta tttttatctc atcttcataa aaaccctcat aatcatattc
    26221 aatagcatgc ttaatagcat agtgttcagt gtcataagtc tgaagtacta cttttccctc
    26281 tttatcagct ctccctgctc ttccagagac ttgagttatc aattgaaagg tagtttcaaa
    26341 acttttaaag tctggaaaat ttaatatcat gtctgcagac aaaataccta ctaaagttac
    26401 attctcaaaa tccagccctt tacttaacat ctgtgttcca ataagtacat ctgcttcttt
    26461 atctttaaat ttatttagta tctcatctaa agcacctttt tttgaagttg tatctttatc
    26521 cattctcaaa gtttttatat ctggaaaaat atattttaat tcctcttcaa ttttttgagt
    26581 tccaactcca aatggcttaa cataagtact tttacattca ggacactctt ttggaatttc
    26641 tttctcatat ccacaatagt ggcatcttcc agtattgctt ttcttatgat aagttaaaga
    26701 tatatcacaa ttttcacatt gaaacacata tccacacttt ctacaagata caaaatttgc
    26761 ataacctctt ctgtttaaaa atagtatcac ttgattattt tcttcaatcg cataacgtat
    26821 ttctttttgt aatttcaaac taaatatact tctatttcct ttatctaatt catctttcat
    26881 gtctaccact tcaatgtttg gaagaggctt atcatttgct ctacttttta tatttataag
    26941 tttgtattct ccagattttg ccctataata ctcttcaatt gagggcgttg ctgaacctaa
    27001 aataagagtt atattatttt ttaatgccat aaatctagca acttctatag cattaaattt
    27061 tggattcttc tcagacttat atgatgactc atgacattca tcaattatta ttaagcctaa
    27121 ggaattaaaa ggtgcaaata aagctgacct agctccaatt aacactctta ctttacctgc
    27181 tttgacagct ttgtaaacat catgtttttc tccttcagat agtttactgt ggaacactcc
    27241 aactaaatct ccaaacctac tctttagcct atctattgtt tgaggagtta atgctatctc
    27301 aggtactaag aatatactgt ctaagccttg atttagagca aattctatta tttccatgta
    27361 aacttcagtt tttccacttc cagttactcc atgaattaag tatggttttt tatcatctac
    27421 aaacatattc gactttatct catcaactgc ttcttgttgt tcattgttta attttatact
    27481 ttttagtacg gatttgtaaa tactttttgg ctctctataa taatccttaa attctagggt
    27541 tattagcttt ttcttactta gagaatttat actttgtttt gaagcattta ataaatccaa
    27601 taaatcattt atctctacat tttcattatt tttaagaaaa cttaatatct ctttttgttt
    27661 acttcccaca tttattttat tttgctctat ataatcgtca atcttatcac tttctaaact
    27721 caaagatata taacatactt tcttttcatt tttgtgattt ttatattccc aacataattt
    27781 tataattcca tttttattca ttgtgtacaa agaactattt aagtttggta tatattttaa
    27841 cttatcaacc ttaattttac ctttactatc aatcactttc tctactattt ctctattttt
    27901 atcacttaaa gttgatattt tttccttcaa ttcaatctca tttaatccac ttaaactttc
    27961 acctaatagg actactttat aattatttaa tttgtatccc tttggatata tcaaatttat
    28021 acattctata taagtacaca aatatctatt tttcatccaa taaaccaact ctaaatcttc
    28081 ttttctaaat attggatttt catctaatat atcaataatt tcttttattt ttattttttc
    28141 atctaagcta tctgtaaatt gaaatacaaa ggcttctgtt ggtttattac cttttccaaa
    28201 tggtactaat attctgtgcc cgatttttat tacatcagat aaaaatacag gaatttgata
    28261 tgtaaataaa ttatctgtat atatagtatt acttctaact attacctttg catatttttt
    28321 cattataaaa cctctactta aatttaatat attgttcata ttttaatata ctttacaaga
    28381 tattaaaatc tcagaattta taagcaattt caagttatta atattaactt tattttaata
    28441 attaactatt aattatattt tatactttat gacaaaataa atgctgaaaa ctacaattta
    28501 actgacattt gcgagttttt actcgctaaa attaaattgc agctttcagc cactttagct
    28561 gtgataaaat acacaaatat catatttaaa aaaggtctta tttctcaagc aacgctttaa
    28621 ctttatctaa aataacattg gctacttctt cttttttcat cttaggatac tcagtaatat
    28681 ttccctctac atctattatt tttacaatat tagtatcagc tctaaaacca gcaccttctt
    28741 tagttaaatc atttgccaca ataaaatcta aatttttctt ttttattttt cctttggcat
    28801 gttctataag gtcattagtt tcagctgcaa atccaattag tatcttatct tcttttattt
    28861 ttcctatttc ataagcaata tcataatttc tacttagttc tattgataaa tcatcattct
    28921 tctttttaat ttttttgtca gaataagttt ttggtttata atctgcaact gctgcacttt
    28981 gaattactat tttattttca cttaaatttg atactactgc ttcatacaaa tcttgtgctg
    29041 actctatttg aacaaatttt ttaagatttt gtggaataga aagatttgta ggacctgata
    29101 ttaatgttac atcagcacct ctagctatag cttctcttgc tatagaatat cccattttac
    29161 cagaagacct attagttaaa tatcttactg ggtctatact ctctacagtt ggaccagctg
    29221 taactatcat actttgacct tttaaatctt gctctttagt aagattagtc aaaacttcct
    29281 ctactattat atctggatta gctaatttgc ctgttccaat atctccacat gcaagccttc
    29341 cactttctgg ttcaataaat ttatatccaa aactctttaa agtttgtata tttttttgaa
    29401 caattggatt ttcatacata ttagtattca tagctggtgc tataagaacc tgtgctttgg
    29461 ttgccataac agtagttgtc aacatatcgt cagctatacc atttgcaatc ttgcctataa
    29521 catttgcact tgctggaact attaagaata aatctgcttt ttttgctaat gatatatgtt
    29581 caacttccca agtttttggt tcttcaaaca tatcttctac tacataattt tgactcagcg
    29641 attgaaatgc aagtggttta acaaattctg ttgctgattt tgtcattata acatggatat
    29701 ttgcatttag tttttttaac ttacttacaa catcacaagc cttatatgca gctataccgc
    29761 cacttatgcc aattacaaca gttttatctt ttagcatgac cttactcctc ttctgaaatt
    29821 tgttggtgtt gctcagcatg atgtctagct tcttctatct ctatttcctc ttctgtcaat
    29881 aatctatatg ttatttttcc acttgcaact tctttagttg ctacacatac aggcttttcc
    29941 ttagttttat ttgaaacata tggttcttct ccatcaatta attttcttgc tctctttgaa
    30001 acagtcccta ctaaatagta tctgttgtct attttttcta gtacctcatt gatagatggt
    30061 tttaacataa ttataattcc tccttaaatt tctctattat aatattttta tatctgctaa
    30121 ctttattctt ttcagatgat attatacctt ctatttcttt agcagatgtt tttacatctt
    30181 cattaaatat aaaataatca taatccttaa tcattttaat ttcttcatat gcacagctaa
    30241 atctcttctc tatttcagct tctgtttctg tacctcttcc aacaattcta ttttttaatt
    30301 cttcaagtga tggtggtagt acaaatataa atactccctc tgggcaaact tcttttattt
    30361 gttttgctcc ttgcatttca atctccagta atacatcttg tcctttttct aaacattcca
    30421 ttattgccgc ttttggagtt ccataaaaat tatcataaat ttgagcatac tccaaaaact
    30481 cacctttttc tatcatctct tcaaactttt ccttacttat gaagaaataa tttactccat
    30541 caacttctcc agttctgggt tttcttgtag tagctgatac agaaagtttt attgtatcat
    30601 tttctttaag tagttctttg caaatagtac cttttcctgc acctgatggt cctgatacaa
    30661 ctagcaataa tccttttttc acaaacattt aagcattccc cttctaatat tgtattctta
    30721 ctctatattt tgtatttgtt ctcttatttt ttccaattcg ctttttactt ctactactaa
    30781 attagttata tttatatcag atgacttcga acctatagtg ttagtttctc tattcatctc
    30841 ttgtattaag aaatctattt ttctacctat agagtcgtct ttaaatatag tatttttaag
    30901 ttgccctata tgacttttaa atctaactat ttcttctgtt atactgcttt tatctgcata
    30961 tattgcaact tcttgtgcta atctattctc atctattata cttgggtcat ccagtaattc
    31021 acttattctc aaattcaatt tttctctata atcttctaca acactacttg aatatttttc
    31081 aatctcttct atatgatttt ttaataaatc acatctcatg gcaatatctt cagctaattt
    31141 tttaccttct tcacttctca tttctcttaa tttgattaat gcatcttcaa ctgcttgatt
    31201 caacattgac cacaataaat cttcatcttc ttccttttct tctattttca caatatcagg
    31261 aaactttgca acattcataa cgctaatatc atctataata tcaaatttat tttttatttc
    31321 ttttagtatg tctatatact gagatgctaa tccctcatca aaatttaagt ttacatcttc
    31381 tttgcctaat aagtcaaact ttatgtataa atctactctt cctcttttta cataattttt
    31441 tactaaattt ctaactttat cctctaaaaa tgaaattttt cttggaagac gtatgtttat
    31501 atctgaatac ttatgattta tcgttttaca ctctactaaa aagtaataat tatcatcctt
    31561 gtattctcct cttccaaaac cagtcatact tatagccatt aattaaacct ccaaaacacc
    31621 ttcacatatt tttactgctg gacctgtcat ataagagaaa tctcctacat ctattttaac
    31681 tgttccacct tgagacgtta catttacact actttctacc atattaagta aattgcacac
    31741 tattgctgat gcagtcatac cagtaccaca acctaaagta tatccacaac ctctttccca
    31801 agtataaaca tgtatattat acttatcttc tacctttaca aaatttacat tcgttttttc
    31861 aggaaatatt ttattatttt caatctcttt tccatattta caaacatcat ctacatctaa
    31921 ttcatctact ataactactg tatgaggaac ccccatcaac atagaagtaa ctttaagctc
    31981 cctatctaaa acctttatac tttcttgcac aaaacgttct ttatttgtaa gtacaggaac
    32041 atccttagct ataaaacttc cttttcccat attgactctt atagagttta tttctctatt
    32101 ggtaagattt atttttatat cttttatacc atctaatgta tctactgtaa aactttcttt
    32161 tttaactata caattatcat aaacaaattt acaaaaacat ctaaggccat ttccacacat
    32221 agctgctctt gaaccatcag aattataata taccatttct acatctgcaa cttttgaatc
    32281 tttcacaact aacaatccat ccgctcctac agaaaatctt ctatggcata ctttttttgc
    32341 taaagcagta taatcagatg gatttatctg gtcgaatctt ccatctattg ctataaaatc
    32401 atttcctatt ccatgtagtt tccaaaattt cataagtatc gctccttcgt aaattaacgc
    32461 ttaaactatt ataacataaa aaaattccca taaacttata atttatggga aaagttttgt
    32521 aatgacaact ataatttgag gatgtgaggg agagttgtca ttacaattag ggtaattata
    32581 ttatgttttt aagctagttc tttctatatt tatatattaa tatttctata tgaattttat
    32641 gtatgtttta tttaaactgt ctatgaattt tttaattaaa catctggtaa ccagctataa
    32701 tccttttagt agatatctat taacatacac ctattaattc tttaagtgtt tttaaaacat
    32761 agtctaaatc ttccttagta atatctacat gagttacaaa tctatattca ccattttcca
    32821 ttttattaat ttttatattt ctttcaaaaa attcttttat taaaacatcc tcttttataa
    32881 tatcttcact catcttaaaa aataccatac ttatatctgg attaacattg tttacttcaa
    32941 tgccatcaat tttatttaat tcacaagcta aatattttgc attttcatgg tcttcattca
    33001 atcttaaagt cattttttca atggcaatta taccagctgc tgcaactata cctacttgtc
    33061 tcattccccc acccataact ttttgctttc ttctagcttt tgctataaat tctttacttc
    33121 cagcaagtat agaacccatt ggtgcagcta aaccttttga cacacagaac ataacactat
    33181 cacaacactt tgctatttct ttagcttcta cacccaaagt taatgctgcg ttaaataatc
    33241 ttgctccatc taaatgtact ggtaagttat gtttctcagc tattttttta atttctctta
    33301 aattatcaag actcacaact gttccacctg aatatgcatt ttctacacat ataagccctg
    33361 tctgtggttc atgtatgtca tctcttctaa ttgccttttc aacaagttca ggatttagag
    33421 ctccactttc gtcttcatct atagttctaa gctgaactcc agctattaca gcaggtgccc
    33481 caacctcatg agttacaatg tgataacctt taccaataat tatttcttgc cctcttaggc
    33541 aatgagtaaa tagagctaat tgattcccaa aagttccact tggaaggaaa atagcatctt
    33601 cttttccaac tttagctgct gctaattctt caagtttatt tacagtaggg tcatctctaa
    33661 agattgaatc tccaacagga gcctttgcca tagcttctct catttcgtca gtaggcatag
    33721 taacagtatc acttcttaaa tcgataaatc tcattttttc aaccttcttt catatttata
    33781 tactatagaa ccttaaaatt gattttttct gtaaagttca tatactttca tagcttatac
    33841 tctacacaat aattatacta tatttacttt atatttaatc tactttaaat tattaatttt
    33901 aaaaataaag tttcctctct aataagtata aataattata caatttaaat attaatctct
    33961 atcgtttaaa ttccccctag tcacaaagcg tatattatgt gtataattaa tttactgact
    34021 cattttggtc aaagaaaggg gtgctataaa tggcattaga tggattagtt atacattcaa
    34081 tagtcgatga attatcatca aaacttacag gtggaaaaat agataagata catcaacctg
    34141 aagatgatga ggtaattttt aatataagaa ataataaaga aaattttaga ttggttttaa
    34201 gtgcaagtgc ctcaaatcct agagtttatc ttacaagtaa ttatcaaaaa gaaaaccctc
    34261 taaaagcgcc tatgttttgt atgttactta gaaaatacat acaaggtgga aatatagtag
    34321 aaatttctca aataggtttt gaaagaataa taaaaataag tgttgaatct ttagatgaat
    34381 taaaagaaaa gacagttaaa aatattatga ttgaaattat gggaagacat agcaacataa
    34441 taataactca tggtgaagaa aataaaatta tagattctat aaaaagagtc ccttttagca
    34501 taagtagagt tcgtcaagtt ttacctggtc atgattattc attaccacca gaacaaaaca
    34561 aactcaaccc tcttgatgat atatctaagg atttgtttat taaaaaccta gaagaattgg
    34621 aaggacctat ctttaagtct atatattcta aatttctagg tataagccct attatagcta
    34681 aagaaatttg ctacagagca ggtgtaaatc aaaatgctat cataaaggat atatctgatg
    34741 aacaatttga ttctttacac aaagtatttt gtaatttatt caatgatata aattctaaca
    34801 aatactcccc ttgcattatt atagataaaa aggtggataa ggtagttgat ttcagttgta
    34861 taaaccttac attatttagc gatttatcat atataaataa ggatagtatg tctcgtattc
    34921 tggaagattt ctatagaact aaagatatta aagatagaat taatcaacgt tcatctgatt
    34981 taaagaagag tatatctgtt aagcttgata gactttataa taaacttaaa aaacaagaag
    35041 aagaattatc agaatccgaa aatgcagaca tttataagat aaaaggagaa ttgattactt
    35101 catatattta tatggtagaa aaaggtatgg aaagtattga agttgctaac ttctatgatg
    35161 aaaattgtaa tgatgtaaca atagaattaa ataaaaactt gacaccatct gaaaatgctc
    35221 aaaaatactt taaaaagtat aacaaaatga aacatgctaa agtcgagata tctcatcaaa
    35281 tttccttaaa taaggaagaa atagattact tagaaaacat aattttaagt attgaaaact
    35341 gtgaaaattt agctgaatta caagatataa aagaagaact tgctaaggtt ggatatatca
    35401 agactcaaaa gaaaaacagt aaaaaggata ctatcccatc tacaaaacct catgaatttg
    35461 tgtcttctga tggatttaaa atattggttg gtaaaaacaa taagcaaaat gactatctta
    35521 cactaagact tgctgataat gatgacttat ggatgcatac aaagaatatt cctggttctc
    35581 atgtaataat aaagtgtgct ggtaaggaag tccctgataa tactgtattt gaaggagcta
    35641 tgctagcagc attctttagt aagtcaaaac tttcttctca ggtgcctgta gactatacta
    35701 agagaaaaaa tgtgaaaaaa cctagtggtt ctaaaccagg tatggttatt tatgaaacta
    35761 acagtactat ttatgttact cctgaagaag aaacagtagc caagcttaag gttaaatctg
    35821 aataaattct gcactaaata caaaataaat gttagacaac tacacattat cattctaaat
    35881 aaaaatagtg gccttcttat aaagtacaat aataaggcca ctttctaatt agcttacttt
    35941 taattttcta acaaaatact tttctgtttt aataactata cttatattcc caacaaatat
    36001 tttcagtctt cttatataga tgtaattaaa aagttaacac taaaagctat tttttaattt
    36061 agtgatttgt tttagtaatt cattatattc tgattcatac aattcttttt ttagattatc
    36121 tttttctata gataacatag atataacagt tgtaagtcta ttttctaata ctagaagatt
    36181 ctctttttta atttgtttgt ctctactagg agttttttta tttctgctaa ttatatattc
    36241 gtcataatta caatcaaact cccttatttt agcatctttt atctctataa tatagttaca
    36301 aatatgtgat acaaatactc tatcatgaga cactataagc atagttttat cagtatttat
    36361 cagtgccttt tccagtgctt ccatagattt tatatctaag taatttgttg gttcatcaaa
    36421 tactaaaaaa ttattatctt ccaatattat tttacatagt gctattttta ccttttctcc
    36481 accactaagt acttttactt ttttgtagac atcatcacct ttaaacccaa ataggcttaa
    36541 gtttatcctt ataaaagatt catcaaatga actattaact ttagtattgt atagaacact
    36601 cttttcctca tctaataaac tttgattttg gtcaaaataa cctactttta ccttgttatt
    36661 tatttttata ttgtcatttt tatcagccaa tatttctttt atcagagtac tttttccaca
    36721 cccattatca cctaataatg ctatcttttt acctcttttt atcttaaagg aaacattatc
    36781 taacaggagc ttattttcta actttagagt catatctttt acctctacta gattttcgct
    36841 aattatctcc ataccatctt gaatcttaat gttcatttct ttagaaactt taggtttatt
    36901 ctttacctca agtttatcaa ttctgctttt tatagccttc acatttgagt ccaacttttt
    36961 cttattagtc tgaccaccca ttttgtgcaa cctagcttct gaattaccca ttctttttgg
    37021 tgtctttctt atgccatcac ttaaagcttt tttatataaa agagcttttt caagcctttt
    37081 tttctcttta acatattctt gatactcaaa atcagctctt tttacttctt catctttttg
    37141 cattaaataa tcagtgtaat tgcctttgta agcttttagt tttccatctt ctagttctaa
    37201 tatagttgta cataactcat ccagaaaacg tctatcatga gatattaata ataatgctcc
    37261 ctcatgcctt ttaaacatat cttccaaaag cccaatgctt tttttatcta agtttgaagt
    37321 tggctcatca gctattatga tatttttctt attactcagc gcatctgcta tttttaactt
    37381 aaccttttcc cctcctgata agtattcttc aaatttatct ggagcattta aaagactctt
    37441 ctccttacta tgactacatg tttcaatatt attttcactc tgacttatat aagaatagct
    37501 ttctgtaagg taagtatatc cttcatcaat ttctatttca cccaatattg cttttaataa
    37561 tgttgttttt ccttgaccat ttgaaccaac tagacctatt ttgtcatttt ctaatatttc
    37621 aagtttatct atatccaaaa ttaatttatc tgcataatat ttctttaaat tctctacttt
    37681 tactaacaac ataaaaaatc cctccttaac acacttaaat ataaggagag attctataaa
    37741 taggcataac aaataaacgt atagactata atctactctc cttaatttaa gcattgcaaa
    37801 taaagccacc aaaataggct tttcaaaaat tacaatactt taaattataa aaaatagatt
    37861 atattctcat tgtcctagtt accttgccct ttctttcatt tatttttaat cattatatca
    37921 acattaatta caaatgtcta tagaaaatta actaatttta gttattcaat atacaactta
    37981 ttctttaaat ttattcttct tcaactttaa aatcctgatt atttaaaatt ctgtttaata
    38041 caattccaac aattgcagct aaactaagac cagttatctt tactgtactt gttataggga
    38101 ttccaacaga aataccttta ttagataaat atgttgttcc aagacctatt aataatataa
    38161 ctgctattat taatatattt atcttgcttt ctacacaaga actgtccctt atagttttta
    38221 atcctacata agttatcatc gaaaatagca ttatactaat tccacccata actgaacctg
    38281 gtatactttg aagaaatcca ccaaactttc ctacacatgc aagcaatata gcaaatatcg
    38341 ctgtacgtct aagtattgaa gggtcatagt ttttagttat agcaagtact gctgtatttt
    38401 ctccataagt tgtattggct ggtcctccta aacaccctgc aactatagtc gcaaatccat
    38461 ccccaagtaa tgttctattt aatccgggat tttctataaa gtttttacct actacagcac
    38521 cattagtagt catatctcct atatgttcca taaatacagc taatacaact ggagatataa
    38581 tcacaattgc tcctaaactg aacttaggaa ctgtaaagtt aggtattgca aataaacttg
    38641 cttctgtaat agtagttata tctactaatc ttaatatcaa acagattata tacccagaaa
    38701 aaactgctat taatattcct aattgtttta taaatcctct accaaactta ttggttaaaa
    38761 ttgctattgc taaagttata aatgctatta caaaattagc tgaagccata ctaaaagctg
    38821 ttggcaataa atttaatcct ataactacta tcatagctcc tgtaacttgt gcaggaaaat
    38881 ataatttaat tttatttaca ccaactattt ttactataat cgacattata atataaatta
    38941 atcctgctac tattatacca ccttgagcat atgctaaatc tccaccatac gcctctttag
    39001 ctgctagtat aactggtata aacgcaaaac ttgaacctaa aaaggcaggt acttttcctt
    39061 ctgtacaaaa atgaaatatc aatgtaccaa caccagcaca gaaaattgca actgacggat
    39121 taaaacctgt caaaatggga actaatactg tcgctccaaa catggctaat agatgttgta
    39181 aagacattat tgtttttttc ataaaaacct ccaaaattat tatatataaa taaatcctct
    39241 gtttaattaa tatcttttaa ttaattatca ttccctagat tctatttttt aacctctata
    39301 tacttattat ataatttatc attattttac attttacgac atcaaaaact caaataaagg
    39361 agaataaaaa ctacattaag actcacatcc ataaaattat aatatttatt ttgtgcaatc
    39421 tatgtaagct ttatcctcct ccctgactat tcaatgctaa gcttttatat aatacttaaa
    39481 actaattatt ctttgattgt aactgaatct tctccatcaa tttctaataa actgacagat
    39541 ataatttcat gtctagaagt aggtacattt tttcctacat aatctgctct tataggcaac
    39601 tctctatgcc ctctgtccac tagaactgct aattgtattg atttaggtct tcctatatct
    39661 ataatcgcat ctagtgaagc tctcacagtt cttccagtgt ataaaacatc atcaaccaaa
    39721 actactgtct tatcatttac attaaaatct aaataagttc ctttaactac aggttcaaca
    39781 tgaatttttt ccaaatcatc tctatataaa gttatatcaa tatctcctgt atctactttt
    39841 gttccttcta tttgttctat tttcttagaa attctatttg caattggcac acctctagtt
    39901 tttattccaa ctaaaactag attttctaca cctttatttc tttcaattat ttcatgactt
    39961 attctagtaa ttgctcttgc tattgccttt tcatccatta attgagcttt ttctaccata
    40021 tcataattat tgtcaaagat ataatatatc tatttgacaa atctactcct ttcttttaat
    40081 tttttataaa tttattttta tttaaaattt caatttaaac aacaaaaaac ttctcatcac
    40141 aagacaagaa gctcttatat aaaaaatata cagtgtaatt tagcaattgt cttacgatat
    40201 ctctgtatcg tttaaagata attttttaat ctatcaactc aaattatata tttatatttc
    40261 aaatttttca agctttttta aacaaaatac tttaatataa gatattttat ttaaatttca
    40321 ctaaatttat ttacttatat aaaaacaaaa aatgatttat aagtattata caaatggtta
    40381 ttttatcttc ttaatagctt ccttaaaata ctcaggtaat tctgaattaa attcgatata
    40441 ttccttagtg gtaggatgta taaatcccaa cttcttagcg tgcaaagttt gtccttttaa
    40501 tttaaattta gtttcttttg gaccatatac aaaatcacct aaaagtgggt gatttataga
    40561 caaagcatga actcttattt gatgagttct accagtttca agcctagctc tcatatgtgt
    40621 aaacttatca aatctttcta caacttcaaa atgagtaatt gcattttttc catcctttac
    40681 tacagccatt tttaatctat ccttaggatt tctccctata ggtttattaa cagttatttt
    40741 atcttcttta accacaccat agcatataaa ttcatactct ctagttatag tatgttcctt
    40801 taactgttct gctagaaaat tatgtgcata attgttctta gctatcataa gaagaccaga
    40861 agtatctttg tctattctat gaactatacc aggtctaata actccattta ttgacgacaa
    40921 cttatcttta caatgatata aaatcccatt tactagtgta ttttcatagt ttccaggagc
    40981 gggatgaaca accatatcct ggggtttatt tattattaag acatcatcat cttcatatac
    41041 aatatctatt ggaatatctt gaggtaaaac ctctaatact ttaggttctg gtatctctat
    41101 aacaatatta tcttcctctt taactagata tttagctttt tctactttat tattgacctt
    41161 tacttttcca tcttttataa ttttttgtat ataacttctt gacatatcac ctaattgttc
    41221 tgctagataa atatcaagtc taacttcttc ttcctcttca agtactaaaa actcttttac
    41281 ttcatccatt atatcaccta cttttacttt caaaaaataa aacatatata cataaaaaca
    41341 cagttcctac aactacaaat acatcagcta cattgaatac atattcccat ataactctaa
    41401 agtcgaagta atctaccaca aaacctaatc gtactctatc aattagattt cctaatgcac
    41461 cagatataat taatataatt cccaaccttc caaatatatg tactttcctt gtattaagat
    41521 agtataatcc aaatactgtt gcaagtaatg caacaattat aaatatccac tgattatttt
    41581 gtaataatcc aaatgctgca cctctatttt cgacataagt taaatgaaat acattattta
    41641 ttattggtat tgttgaaaca tctaccaaat tattcaatac ccatatttta gacagttggt
    41701 ctaagcctat gagtagaatt attattaata tatatagcaa tgatttttcc ccctataaat
    41761 tatttaaaaa ccaattttat ttgaaacaca ctattattat tatacaaaaa aaatgctcta
    41821 aagagcaact ttattaaaat tgtattttct taataaagct agagcaaaat ttaaaatagt
    41881 accatctttt ttatattgca gattgctaca tatttaaaat catattatta tgtataaaaa
    41941 atttaaaaat aacatactaa ttaatacttt ttgtgtgttt tatagattaa agattaatga
    42001 tgtctgtact ttaaacttac aagcaccact aatcttcaaa caaatatttt tacttttgca
    42061 cttgcttatt tttatctaaa tgttgtataa gttcagatac tgttacgaat ttatatcctc
    42121 tctcttttaa tttaggaatt actacttcta aagcttgtat agtttgtgat ttatcatttc
    42181 ttttagtgtt ataatcatgt aaaagtatta tattaccatt ttggaccttt gtaagaatag
    42241 tatttataat tgtatctacg ccagggttag accaatctct agggtctaag tttgaccaaa
    42301 gaattatatt catgccttta gaaactataa tatcacagac acttttactc atggctctat
    42361 atggaggtct aaatatcttt ggttctactc ctattacact ttttataata ttttgtgtat
    42421 ctgttatttc tttttcaaca ctaccataac tattttttgc aacatttata tgtgtaaatg
    42481 tatgattccc tatttcatgc ccctcatcat attgcctttt taataattct ttgttatatt
    42541 ctactttttc tccaactaca aaaaaagttg cttttacatt atttttcttt aatatatcaa
    42601 gtatttgtgg tgtaaaatcc tcatctggac catcatcaaa agtcaatgct agaatctttt
    42661 catcctcatt tccttttttt attattacat cttcataatc gtcttttata ttgtcattta
    42721 aagtataggt ttcttttgaa ctattttgat tatgtgtatt atggttatat gtatatacac
    42781 ctactatgga taataaacat atacatatac cccatattgc tttcttcatg tcattacctc
    42841 ttttctaatt cattctaaca atatatgatg tcaggcttct aatctctcaa tgttccattt
    42901 ttatttaaat cagttaaatt tgttaggtct tctgaataaa agttagaatc ttctacatca
    42961 ggattttgca ttgcatcacc taataaagca ttttcttttt ttgcacaatt gttacataaa
    43021 tttgtatcag gtaatatatc taatctttct aaatctattt gattgtgaca taaatcacaa
    43081 aacccatatg ttccattttc tattttagat aatgctgaat ctatttgata cagtcttcct
    43141 tcttcatgat ttattaaact attttgcata ttttgcatat ataaatccgt tcccatatct
    43201 ccaatatgat tatcataact agataattct cccgatgaat atttttcact agtatgttta
    43261 gtagtgtctc caaacaaggt attatctttc atatctacga ctaaattagt taacttttct
    43321 ctttctttta ataatttatc tttgtatttt ttagtatcca ttttcaacac ctctaatttt
    43381 aatatttata tcataaaaat agtatgtgga aaactaaatt aaaaatacaa taaaaaacaa
    43441 gatttgattt tttcaaaaaa aattgtaggt aaacttaaaa ttcacctaca aattctttac
    43501 atatattttt aatataatgt ttttagtttt tgataataat tacattaact tgctaattta
    43561 tgagcatttt gctcttttat atccttagct tttttaaaaa ataaaagtcc aaggattatt
    43621 gcaactacaa tacctattcc attagatata ttaactggaa gtctaaatcc ttcttttgcc
    43681 tgcattatat aactaaatgt tactacagtc ataaaaagtg ctggcaatgt agttatgtaa
    43741 tgatttttat ttgctttgac taaatatgca gaaccagtcc acaacattat catagcaagt
    43801 gtttgatttg cccaagagaa atatctccaa attatattaa aatctataaa tgtaagggca
    43861 acccctacag caaataatgg caaagctatt aaaaatctat ttttaactgc atcttgatta
    43921 taattcattg catcagctat tgttaatcta gcacttctaa atgctgtatc ccctgaagtt
    43981 ataggacatg ctacaacacc aagtattgcc aaagcgcctc caataggtcc cattaatcca
    44041 acagatactg tatttacaac agttgctgct ccaccatcat taaatattac attaagctga
    44101 ggtataccat ggaaatatga catagctgct gctgcccaaa ctaaagctat tataccttct
    44161 gcaaccattg acccataaaa tactggtctt gcctcactct ctttctcaac acatctcgcc
    44221 ataagtggtg attgagttgc atggaaacct gatattgctc cacatgctat tgttataaat
    44281 aagtatggga ataaaggtgt tccatttgga ttcatatttt gtaaatttat atttggtatg
    44341 ttatacccct ttattattaa tcctccagct acacctactg ccataattaa taatgctgct
    44401 ccaaataaag gatatatttt accaatcaat ttatctattg gtaaaacagt agccataata
    44461 taataaagta ttatcactcc aacccatatt tgtgcgttta cacctgtcaa tgtctttaat
    44521 aatcctgctg gacctgttac aaatacaact ccaaccaata ctaaaagaat aacactaaat
    44581 attctcattg ctatttttgc accatttcct agataaagac ctaccaactc tgatgcagat
    44641 gtacctttgt tcttcattga taaatatcct gaagcaaaat cgtgtactcc acctgcaaag
    44701 attgttccaa acacaatcca caaaaatgct gatggtccaa ataacgcccc ttgtatagct
    44761 ccaaatatcg gacctaaccc tgctatattt agaaactgaa ttaaaaagat tctcttccat
    44821 ttcattggca cataatctac tccatcccta caagctatag ctggagtttg gtttttgtca
    44881 ttgattccaa aaaccttttc tacaaaagta ccatagataa aataacctac tataagtact
    44941 actattgaac ctaaaaagct taccataaat tcatcccctt agtttttata taattgcttt
    45001 ataaattttt atgagtttaa gaaaactatt tccagttcaa atagtaatac ttttttatgc
    45061 taatataaat attaattaca ttaagtgcat atttaagtac atgaaatgac tttatatatg
    45121 cattaacagc ctaaattctt ttactttgct tctgcttaca gttacttcat agtcactatt
    45181 ttttaatttc aatatgtatg tattgttaaa ccatggtata atttctttta ctttggttaa
    45241 atttacgata taagacctat gtgttctaaa aaatgtttta tcatttataa gattctctac
    45301 ttctgatatg ccttctttta atataaactt ttctttctca gtatatataa atgtctgcct
    45361 ttcattagct tcacaataat atatatcatc aatatctatt acaaccaatt tatcaccttt
    45421 ccaaaggcta attttatgtg ttatttcttc tatctcctga tttactgtct cttttttata
    45481 tttatataaa ttactattgc tattagacag ttcaatatca ctcatctcac ttttttctaa
    45541 tttattcaac atagaaataa ttctctcttc agaatatggc ttcagtacat aatcaaatac
    45601 atctaaagaa aaagcatcta ctgcataatt ttcatacgct gttataaaaa caattttagg
    45661 ccttgattta aactgattta atgtttttgc aagaagcatt ccatcgagat gaggtatatt
    45721 tatatccaaa aaaattacat ctattttatt ttcctgaata aagtctaaca cttctatacc
    45781 attagtaaat tcatttacta cctctatgct acttttattt tcaataaaat atcttaattc
    45841 ctttcttgcc ggaaattcat cttccactat tatagctctc atacttctac tcctttacat
    45901 aaaatactat caaagtccca ttgtctgttc ttcttatatt aagccctctt ccatacatca
    45961 gtttaagcct taaatgtaca ttataaagtc caatcttatt ttctggcata ttatcttgat
    46021 atacattatt tataatttcc tcacttatac ctataccatt atcctctatt gatattctca
    46081 cagtattttc taatgaataa ggtaactttt ttatggatat tttcactaca ccagctctac
    46141 cactttctaa aataccatgt attattgcat tttccactaa tggttgtata atcaaacttg
    46201 gaatctttat atttacatct tctatatcat aagatacagt tagtaattct ccaaacctag
    46261 ctttttctat ctctacaaag gatttaactt gttcaatctc tttatttata tcaattaagt
    46321 tatcactata ttcaagatta tatcttagat aagttgataa atttattatt aactctctag
    46381 ccttatctgg gctaaatctt ataaatgaag ctattgtgtt tagggaatta aacaaaaaat
    46441 gtggattaat ttgtctttga agtgctttta tttctgcttt atttctcgct tctatatcct
    46501 ttttatcttt ctcaatcccc tctactatag atataacaaa tcctattcca atctgtccaa
    46561 caattaaagg taaatatatc ccaacaatta tttgaattgc taaagaatgt ggatatgata
    46621 ttaagtatat aagtagtata gtaaaacttt cagaaatcat acctaccaat ataccataca
    46681 ttactctatg ttgctttggt atcctcttat atagaaatcc tgataataca cctgctagta
    46741 tactcgataa aagacatgga acagatgtta tccctccaat atccataaaa tatctatgaa
    46801 tccccgaaaa aactcctgct gtgataccta ccattggacc aaataaaatg cctcctgata
    46861 ctatagatat tattctagtg tttactattg accccatata atttatacca ctgtaagttc
    46921 caaatatgcc taaaaaagta aaaactaatg ctatacagac caaatcatta aaactatatt
    46981 cttctttttg aaatatctgc ttaaatattt ttaactttgt tattagaaga aacagtacta
    47041 caatgaggct tgtcttttct attaatgcga ttaaaattga tgttttcata ttccaccttt
    47101 aaaaaataaa tttttacaca ctctaaattt attatgtttg ttgtaactta tatatttgaa
    47161 gtaatcctat ctcgacattt tccacattta accttttaat taaataaaaa atggatatac
    47221 ttctattaac aactaatact agctgactaa cacaagcttg taataacttg tagttatcat
    47281 taactctaca attctagtat ttaattttat actttcgaaa tctcttttct tagaagtaat
    47341 actttcgaat attatataat acaatgttat gtagattctt actcatacaa catatttctt
    47401 taaaaatttt atactattct ttgttcaaat atctcatttg atttaattgt gctaaacaca
    47461 cattatcatc tctctgttat atatttatta tatagccgta tatggataaa gtaaataaat
    47521 cctatattta aaatcatatg tttgatagta aatcattata atgtatattt accataataa
    47581 tttgccaacc ttgaaagtca cttctataat tagaagttaa ataattcttc taaaaaaaat
    47641 acctctaaat tttattttct gaaatacata gttataacta tttttatcac gtataagaat
    47701 aaaaattcca gaaaa
//
LOCUS       DACTZW010000026        46368 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.026, whole genome shotgun sequence.
ACCESSION   DACTZW010000026 DACTZW010000000
VERSION     DACTZW010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 46368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46368
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.026"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            298..756
                     /locus_tag="JAM15_07585"
     CDS             298..756
                     /locus_tag="JAM15_07585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAT6798109.1"
                     /translation="MEFINFVSDKVIDLKMDCKTKEDFFKEIHNKVFDLGFVKEEFGE
                     KILARENVFPTGLNLGDYGVAIPHTDAEYIKEQFISVCTFNEPVVFSSMEDQDEKVPV
                     NLAFILGLNQPHSQLSVLTELMGIMQNKELVDKLMSSTDKEEVLRTLKSL"
     gene            817..1092
                     /locus_tag="JAM15_07590"
     CDS             817..1092
                     /locus_tag="JAM15_07590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAT6798110.1"
                     /translation="MKKILVACGAGIATSTVVCDKVERLVKENNIQAEVIQCKIAECA
                     TKQEGADLIVSTTILPTTYNIPAIKATAYITGVNTAALDKKILDALK"
     gene            1151..2425
                     /locus_tag="JAM15_07595"
     CDS             1151..2425
                     /locus_tag="JAM15_07595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843259.1"
                     /note="with GatAB forms a phosphoenolpyruvate-dependent
                     sugar phosphotransferase transporter for galactitol;
                     subunit IIC forms the translocation channel and contains
                     the substrate binding site; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HAT6798111.1"
                     /translation="MDKLLAVVQYILNMGPTVILPITIVVLGMIFRIKFTKALKSGLT
                     IGIGFVGINLVVNLLTSTLGPAAQGMVERFGLNLTVIDVGWPTTASATWASPVAPILI
                     PVCLLVNLLLLYFNKTKILNVDIWNYWHFIVAGAVGYIVTGSYVWAIFCAILMELLVL
                     FIAEKTAKNVQEFYDLEGIALPTGSTASFAPLGYLVGKFVEKIPGINKIQADPDSIQK
                     RFGIFGEPMMMGIILGIILGALAGYDVAGIFNVGISMGAVMLLMPRMVRILMEGLIPI
                     SESIRDFLQAKYGDRELYIGLDAAVATGHPAVISTALILVPITLFLAVILPGNKVLPF
                     GDLATIPFYMAFIVCFRKGNIVQSVITGTIVIAISLYMATNFADVHTQLLQQANMMPE
                     GTTMVTSIDTGGNLLKWGILKLSQLVSSFGIF"
     gene            2555..3607
                     /locus_tag="JAM15_07600"
     CDS             2555..3607
                     /locus_tag="JAM15_07600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HAT6798112.1"
                     /translation="MKAAVLHGTNDMRFEDIEIKPCESDEVKIKVMAAGICGSDPPRV
                     LKHWKYPVPAIPGHEFSGVIAEVGKDVKNVKVGDRVVAIPFIPCNECEYCKRGLFSLC
                     DDHGMLGAKSFGAFAEYVNIKATNVLPIGDMDFEDAAMIEPLAVAMHGVLNIGVQVGD
                     TVAVMGSGTMGQLVIQGLKIAGAGTIIAVDISDNKLRESKELGADIIINAKDIDPVEK
                     IKELTGGKGVDIALECAGSKITQEQCLLITKKKSKIGFLGIAYSDITLSEEAFENIFR
                     KELELKGFWNSYSAPFPGQEWTKGINLVNEGKIKLKEMVSHRFSLEDTYKAFEMIRDR
                     KEEFNKILILPQGVEK"
     gene            3607..4638
                     /locus_tag="JAM15_07605"
     CDS             3607..4638
                     /locus_tag="JAM15_07605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019595253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HAT6798113.1"
                     /translation="MKAVVKTKPGYDNVEVLEVEEPKATGDKVKIKVEYSGICGSDIH
                     SFKGEYANIKAPVTLGHEFSGIVVEVGEDVKDIKVGDRVTSETTFATCEKCIYCETKD
                     YNLCPTRKGIGTQVNGSFAEYVLSREESIHVLPENVSLLSAALTEPLACCVHAALEKT
                     TIESSDTVLIIGPGPIGLLLAQVVKSQGATVIMSGVTKDKERLEIAKNLGVDRTVNVM
                     EESLADVVNEMTDGNGVNKGFDCSGFMPAVNEALRLLRKKGTFVQVGIFAKKLNEMDQ
                     EAIIQRELQYIGSRSQKPSSWITALDLMASGKVNTEALVTRTVGLDEFKEGITALMNG
                     EEIKVAVKS"
     gene            4730..5542
                     /locus_tag="JAM15_07610"
     CDS             4730..5542
                     /locus_tag="JAM15_07610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HAT6798114.1"
                     /translation="MSTLRDHSNNIRKNIIKMVAEAKSGHPGGSLSIADMLTVLYFDK
                     MNVCAENPKMADRDRFVLSKGHAAPALYATLAEKGFFPEEELITLRKFGSKLQGHPDM
                     KKVAGIDMSTGSLGQGLSAANGMALAGKLDNKDYTVYTILGDGEIQEGQIWEAAMTAS
                     HYKLDNLIAFVDLNGLQIDGSNEEVMNVNPVDDKFKSFGWNVIVINGHSFEEIGNAVD
                     EAKKVTGKPTVIIAKTVKGKGVSFMENNAAWHGTAPNAEQAEQALKDLEGGL"
     gene            5545..6465
                     /locus_tag="JAM15_07615"
     CDS             5545..6465
                     /locus_tag="JAM15_07615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HAT6798115.1"
                     /translation="MGIATREAYGQVLKELAENKDIVVLDADLGKATKSISFKEVAPD
                     RFFDMGIAEGDMIGTAAGLATCGKIPFASTFAIFAAGRGYEQIRNSVAYPNLNVKIAA
                     THAGVTVGEDGGSHQAIEDISLMRGIPNMVVLNPADALEARQAILASIDYNGPVYIRL
                     GRAATPDVNSENYKFEIGKGTVLREGSDITVIATGIMVAKALEAAEELAKEGINVEVV
                     NISTIKPLDEALIKETAKKTGKVVTAEEHSIIGGLGSAVCEALAETKDVVVRRIGVKD
                     VFGQSGTPADLLKHYGLTTEDIVKNIKELL"
     gene            6640..7086
                     /gene="rpiB"
                     /locus_tag="JAM15_07620"
     CDS             6640..7086
                     /gene="rpiB"
                     /locus_tag="JAM15_07620"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HAT6798116.1"
                     /translation="MKISIGCDHGGYELKEYIKENLINKGIEVEDVGTNSKESVDFPI
                     YAKKVSQNVQSKKSDLGILCCGTGIGMSIAANKFKGIRAAVVSDCFSAKATREHNNTN
                     VLCLGERVIGKGLAMRIVEEWLNSSYNGERHARRLQMIDDIEKENL"
     gene            7125..7790
                     /locus_tag="JAM15_07625"
     CDS             7125..7790
                     /locus_tag="JAM15_07625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HAT6798117.1"
                     /translation="MSIICASIMCADQMKLKEELEALEEAGVKLLHCDVMDGIFVKNL
                     AMGPELLKSISENTTIPLDIHLATETPDKYIDMMSYIKPKYISFHVESSTNVKADIQK
                     LRNYGIGPVLAISPQTSVDKIEEYISLVEGILVMTVNPGFAGQKFNLSVLDKLDKLTE
                     ILKDYDNPPFIEVDGNINKDTIKLMNGKKVDIYVVGTSALFNDKPPISYKDKIEELKE
                     SIK"
     gene            7900..9402
                     /locus_tag="JAM15_07630"
     CDS             7900..9402
                     /locus_tag="JAM15_07630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HAT6798118.1"
                     /translation="MGDLYKLQNGTDIRGIAYENDSKEVNLTVEEVKKIAKAFHIWLK
                     EKTKKDKVTVAIGTDSRITGSQFRSTVIETLTNDDCNVIDCEIATTPAMFMTTIMDGY
                     NSDGAIMITASHLPYYYNGLKFFTESGGLEKTDIKEMLDIAVKNDSVDYEEVNKKGEV
                     IVKNLIEDYSNLLIDKIRKGVNSSKNYEKPFSGLKILVDAGNGAGGFFAEKVLHILGA
                     DTTGSQFLNPDGMFPNHIPNPENKEAMESICKAVLDNNSDLGIIFDTDVDRAAIVGKN
                     GNPINKNALIAVISSIVLEEHPKTAIVTDSITSEGLAKFINELQGRHHRFKRGYKNVI
                     NEAIRLNSEGEECHLAIETSGHAALKENYFLDDGAYLIAKILIKVAKLSLEGKTIEEL
                     IENLEEAQEEKEVRIGINKEDFRPYAEDILKDLDSHVKSIDGWSVAPNNFEGIRVNCD
                     ESNGDGWFLLRISLHEPLLALNIESNKIGGAEQIYSKLKLFLEKYDLKGL"
     gene            complement(9714..11306)
                     /locus_tag="JAM15_07635"
     CDS             complement(9714..11306)
                     /locus_tag="JAM15_07635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAT6798119.1"
                     /translation="MVTKLKNLIINDSKAKFILLLLLFLLVSILFEAVYDLNNNFSYN
                     INYYYKEFALPYFYFFGTPVHLSKVELEFVCIGIILSSFLLTILCFTLYKKNKQTKVK
                     FLENVISLFSKVKIELTLILILILLTLRFHAFTSNKIFYNTNLIIYNFIIISIVYIIY
                     ENIKYNNYNLKDMSITYVFFSNLLSMYNKKTINKKLAIVFLISIVVQAIIQYLVLIFF
                     MYIYYAEAIAIVILFTLVNTVFHFYIYNFLSVKFNYINNISKNIKNIENGNLKYKLEV
                     IGDDEISTLAKSINNITGGLETAVDANIKNERMKAELITNVSHDLKTPLTSILSYVDM
                     LKNNDFDRETINDYINILDKKSQRLKLLIDDIFEASKLSSGDVEFNITKTDIRELLIQ
                     SIVEFEDKIKNSSLDFIIETPEYAVFTMIDGKKTWRVFENLICNILKYSMPNTRVYID
                     MFIKEENIILTFKNISNDKLNLKPEELIERFRRGDISRKTDGSGLGLSIAQNIIELEN
                     AHMEIIIDADLFKVMLTFRRVN"
     gene            complement(11275..11991)
                     /locus_tag="JAM15_07640"
     CDS             complement(11275..11991)
                     /locus_tag="JAM15_07640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6798120.1"
                     /translation="MNQNILVVDDDREIVDAIEFYLRPDNFNVLKAYDGLEALDILIE
                     NDIKLIIMDVMMPNLDGLKTTLKIREKRNIPIILLSAKSEDMDKIIGLNMGADDYITK
                     PFNPLELTARVKSQLRRYINLGDFSNTNNSNDTNYILKSGGLELNTDTKIVSLDGEEI
                     KMTPLEYKILTLLMSRKGKIFSSREIYENVWNEDAYSCERIIAVHIRRIREKIEINPK
                     EPKYLKVVWGIGYKIEKLNY"
     gene            complement(12532..13332)
                     /locus_tag="JAM15_07645"
     CDS             complement(12532..13332)
                     /locus_tag="JAM15_07645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HAT6798121.1"
                     /translation="MTFKNKKFTINKYEILSIILVLCLILTGFSSYVNYSHKKFKDYV
                     VFYVQHQDDEVLWAGSAIVNAIKERGKNHVFVVLVSTGCGISVFDKYKKYENLTNIQK
                     SEYRNREFLASLNSLGVIRENIILLPETNTNGNTDFNYMEKIALTFEEKFKNVTHIAH
                     TYKLDDHLQHLKNGSVIQNLYNVGKIKDAKYFVKPKFADKITFNNKIVYKAHSTEDYE
                     KVKNACQQYKIVDELEYREGIGYKSDHKSFDKLLNNKDVPAILHTPNL"
     gene            complement(13647..14378)
                     /locus_tag="JAM15_07650"
     CDS             complement(13647..14378)
                     /locus_tag="JAM15_07650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798122.1"
                     /translation="MNIFDILRDYLLVQVDKYNLNMDMISIVSKSLSSKEAIGNTKRK
                     DFPIIVGKEIMLEADFKGAKGQAFTSTPSTFEGSLKDILSLDLHDNPHDRSLFIASLN
                     AVMKYLGKTDRTIHCKNNEPEVCAKKFPEFIKMEFGNPKVAIIGYQPAIIDNIKDFFE
                     TRVLDLNPEFVDTIQYNVKIEDGIRDYEDVISWADLVICTGSTLCNNSIINFLSLNKP
                     VYYYGTTIAGASNILGLKRLCFCSK"
     gene            complement(14365..15060)
                     /locus_tag="JAM15_07655"
     CDS             complement(14365..15060)
                     /locus_tag="JAM15_07655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAT6798123.1"
                     /translation="MLKIKNLSLDLPNFKLQENSLNINNHEYFVLLGASGSGKTLFLE
                     TLAGRYPSAKGNVSYKENLISNLPPENRNIGFVYQNFELFPNMNVEDNIRFPLKLRKI
                     PIDEQILKANHLSKLMQIEDIKNRYPKNLSGGEKQRVAFARALIAEPDILLLDEPMSS
                     LDYITKKHISKILKDVYIKYKPTVIHVTHDISEAMFFAHKIGIMNNGKINHIFDLNEE
                     IKNKGESFFYEYI"
     gene            complement(15062..15853)
                     /locus_tag="JAM15_07660"
     CDS             complement(15062..15853)
                     /locus_tag="JAM15_07660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6798124.1"
                     /translation="MKNKFFTTLLTGFFAIVFLFIVSPLLMLIIKGISYVPICLKSVE
                     VQYAITLSIKTSLISTIVCLLLAIPVAYFLHITKLPFKKLIIQIINLPMSLPHLVSGI
                     ALLLLFGRMGIGDSIYKIFKLDFIFTKQGIVLAQVFVNLPLTIKILHTSLNESNEKMI
                     FVARTLGCNSWEAFRFIILPNLKTGIISATVMTWSRALGEFGAVAMIVGSTRMKTEII
                     PTSIYLNMSTGDIDIAIGIAVILIFISLTCLMLFEIFFNREVDKN"
     gene            complement(15863..16675)
                     /gene="modA"
                     /locus_tag="JAM15_07665"
     CDS             complement(15863..16675)
                     /gene="modA"
                     /locus_tag="JAM15_07665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAT6798125.1"
                     /translation="MFKKLSVLALAMIISLSITACNSKENKANDESNTKVTTADDSKE
                     KETLFVYSGAGLKKPMDEIAKKFEKENNVKVEYSYAGSAQLIAQIETSHKGDVFIVGS
                     EPIYSKAFEKELVGEHKTVAHHTPAIVVPKGNPANIQKLEDLNKDGVKLILGDKESNA
                     IGKTTQKILEKNNLKSINDNVVSTAATVNEMIVQLTSSKADATIATKDSVFGNEDVEV
                     IEIAKDKNIDQLISAGIVNYSDKKDLANKFINYIESDEAKQIFKKYGFEPVK"
     gene            complement(17310..17510)
                     /locus_tag="JAM15_07670"
     CDS             complement(17310..17510)
                     /locus_tag="JAM15_07670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013859190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAT6798126.1"
                     /translation="MNNGIVKWFNNEKGFGFISMESGDDVFAHFSAIQTSGFKSLEEG
                     QKVSFDIVKGARGPQAENITIL"
     regulatory      complement(17965..18054)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(18234..18434)
                     /locus_tag="JAM15_07675"
     CDS             complement(18234..18434)
                     /locus_tag="JAM15_07675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012422935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6798127.1"
                     /translation="MPKFICNLKKYRQLKELTQEQLAEKVGVRRETIMRLEAGKYNPS
                     LKLAIDISKIVDTPIDELFIFD"
     gene            complement(18436..18786)
                     /locus_tag="JAM15_07680"
     CDS             complement(18436..18786)
                     /locus_tag="JAM15_07680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3796 domain-containing protein"
                     /protein_id="HAT6798128.1"
                     /translation="MIQKKFFMGFCGFLGFLSLRYFSSGNVADLTYIGFFAFFSNFII
                     AKINGDKADERYVQDEKAAMAFTGQLAIIELFILWCITIVSRNVELMCVLLSITYAIT
                     LNVYAIKLYILEEK"
     gene            complement(19612..19782)
                     /locus_tag="JAM15_07685"
     CDS             complement(19612..19782)
                     /locus_tag="JAM15_07685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798129.1"
                     /translation="MHVYQPKTSEYLLNTSAKSYLSSIVFLFDYITKNESRYAFFIID
                     FPFLSLDIFYKF"
     gene            complement(20171..20578)
                     /locus_tag="JAM15_07690"
                     /pseudo
     CDS             complement(20171..20578)
                     /locus_tag="JAM15_07690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861519.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pilin"
     gene            21307..21684
                     /locus_tag="JAM15_07695"
     CDS             21307..21684
                     /locus_tag="JAM15_07695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HAT6798130.1"
                     /translation="MKEEILIEKLLRAELIVMEYLCKKDTLMPKKEIVKEIKQIYGWH
                     KSTIKILLKRLVAKRYLARYIINFQYHYKIIIDNKEYYTFKKKVLKSSKSIKIMRSLT
                     TTHKNVSKEKLDLLDEYYRNLKE"
     gene            21789..21980
                     /locus_tag="JAM15_07700"
     CDS             21789..21980
                     /locus_tag="JAM15_07700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HAT6798131.1"
                     /translation="MKISKLPEAELKVMRYIWESEKVLISREITKSMEQKYEWKDTTI
                     FTVLKRLLKNRVFRNGENR"
     gene            22776..23468
                     /locus_tag="JAM15_07705"
     CDS             22776..23468
                     /locus_tag="JAM15_07705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6798132.1"
                     /translation="MYNILVVDDDKEIVDSIEIYLKSEGFKIYKAYDGMKALEIITEN
                     DIHLILMDIMMPKLDGIKATVKIREERNIPIILISAKSEDTDKIIGLNIGADDYITKP
                     FNLLELIARVKSNLRRYVTLGNYEDTCKEILKSGALELNTLTKEVKIDGENIKMTPIE
                     YKIIELLLENKGRVFSIDEIYEKVWNEESFNSENTVAVHIRRIREKIEINPKEPRFLK
                     VVWGVGYKIEKF"
     gene            23664..25724
                     /locus_tag="JAM15_07710"
     CDS             23664..25724
                     /locus_tag="JAM15_07710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HAT6798133.1"
                     /translation="MEKYRALKLVSLIIISISFPLTILLATIGLAEPKYNIQKTSTKS
                     GIFNISNDFYDSNIFDEGTVASLLSNFKISVDSQLTSEEKSKLQTKSKSIDLSSNDSE
                     YDKIMINEQASEEYLSYLKNVKVYVINTYTGVFYTNTSYGNLDDFKQKTKSYCNIEII
                     NNVGKSSYIKTINGEKFELNNLSMELNGVDEAFEAYVSFPEEPTIEDGIVYTNFQIFK
                     QATEKVRLFFVACLSLAIVCLLSIILYSRIKGEVLKRNNVFLLIYSKIPMEFNVILVF
                     ISIAILTMYALAVSYHIDVIVLVSLSLLIVSNNIFFINVQLSYLENKMCIFKTSIIVR
                     VILWLIKTIREVSNAIKKVSLARKVIVIVIISLALIMVISTRSIGMGLLFSICIFLGF
                     TIYITKRLSYLSYVIEGTERIKKGELDYKIKITGNDNFTSLAENINNIGEGLDRAIEE
                     QVKSERMKSDLITNVSHDLKTPLTSIINYVDLIKKEESIQPEYINDYINVLESKSKRL
                     KLLIEDLFEASRVSSGNIELQISKIDLVQLLRQSIGELEEKLSKNNLYLKLNVPNDKV
                     YIWADGRRMYRVFENLLSNIAKYSLEETRVYIDVYDYGENVKVTMKNISSYELNFDPS
                     EIMERFKRADESRNTEGSGLGLAIARDLVDLQGGKFYIEIDGDLFKANLEFQKYEEEI
                     TNME"
     gene            complement(25930..26253)
                     /locus_tag="JAM15_07715"
     CDS             complement(25930..26253)
                     /locus_tag="JAM15_07715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HAT6798134.1"
                     /translation="MNNNYIFFIIIGMYIVTYLPRVLPMLIFSKKEMPDFLKKIMKFI
                     PVAILTSLTAKDVFFNGDSLYLSIANPKIISFMIVLLVAYKFKSIGISIITGVISIYL
                     FGIIL"
     gene            complement(26246..26947)
                     /locus_tag="JAM15_07720"
     CDS             complement(26246..26947)
                     /locus_tag="JAM15_07720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HAT6798135.1"
                     /translation="MERTQQLKESFIASIPIFLGYIPIGIVGGILLQKSGLSPFQIAL
                     MVTLVFGGSSQFIAASMISTGASVTSIVLTTFIVNLRHFLMSSNLNMYIKNKSPKFIL
                     PFCHTITDETFAVNYEKFTAGNWSDRNAIYLNFFCLISSVLANFIGAFLGESISIDSS
                     ISGFILTSMFIALIVSQIKNKIYIVVFISSIIISVILYALFKINLVIIVASILASLIG
                     FFIEESYCKKEESYE"
     gene            complement(27225..28610)
                     /locus_tag="JAM15_07725"
     CDS             complement(27225..28610)
                     /locus_tag="JAM15_07725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAT6798136.1"
                     /translation="MPINSFENYPMNWKPKRPSKGQILYKALAEQLEQDINNGFLLPG
                     TKLPPQRELADFLDVNVSTISRAFKICEKKGLISGVTGSGTFVSYDTRSNLFLMSSNN
                     KITFIEMGTMNPDFTLEEMNTLFKHIIKEIDFKTIFQYGQRDGAKWQKEAIAKLIYKA
                     GLETTSDSLLPASGGQNAIVAILAGLFQHGDRIGVDPLTYPGIKTAAKMLGIQLIPIK
                     QEDNEISEEGLLYACKNENIKGLYIIPDYQNPTTHIMSQNGRKMIANIASKYNLIVIE
                     DAIHSLLNETHLNPVASYLPNQTIYITSLSKIIAPSLRLAYISTPKQYREALSSALYN
                     INLSQSYFLTEIAYRMITSGEADKLINARRKSARRRNKIINQYLSGYNLLGNEECIFR
                     WLILPDGIMAEKFEIQALKEGVQVYASERFAVGKEKPISAIRIAVCATESTEELKAGL
                     SVLKRLLEEEK"
     gene            complement(29056..29478)
                     /locus_tag="JAM15_07730"
     CDS             complement(29056..29478)
                     /locus_tag="JAM15_07730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HAT6798137.1"
                     /translation="MNTFKTEVLLKYSAKDIFNIFTKSARLNFPNFNEKKAVGTFVQQ
                     KNNKRFKVEITNFEKNRVYEIKTSNKRESTITRYELVHIDLENTKLIFIESESKRNIF
                     GKINSALVRVLFGKRQPEEFNKFIKKLEMELENNSVNL"
     gene            29956..32859
                     /locus_tag="JAM15_07735"
     CDS             29956..32859
                     /locus_tag="JAM15_07735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAT6798138.1"
                     /translation="MELRDKLVNIINTENKKDPLTDVQIAKFLSTTRENITNLRKELN
                     ISNSRQRRYPYLKSAISAILQKNKNISISEITRELMTEGFNISRRVVEELLPKESLEM
                     DVVEESEEESNDPFETLIGNKGSLRNAVEQAKSAILYPPKGLPTLIIGESGVGKSLFS
                     RHMYEFAKQKKIVKESSNFVVFNCADYSDNPQLLLSLLFGYKKGAFTGAEYDTPGLVE
                     EADEGVLFLDEIHRLPPKGQEILFSILDRGKFRRLGETNAERKVSIMLIGATTENVET
                     NLLLTFRRRIPMLITLPPLHDRLLKEKIDLIYNIFQQECNRINAKIFVDKNVIEILAL
                     KKFSGNIGQLQNMIQVLCARAFMKFINSKDEDSESIVVVDINEVLKLKDSFKDAAFQE
                     IEYTEIRKYLKNAIFIPFNLEESSVKGSLLSDEYILPEDIYKTIEKKYYDLKSLDIED
                     IDIENILWTFILNRFADLKFNLDSNEEIFSMSDLNSFVSDSLVKLVKELMNDIVEKNM
                     NLEVNKNMFKYLAIHLEEAIKRIKLNQKIINVNLEKIKIDFSKEYEISKSFAIKIEES
                     IGIKIPDDEIGFITLYIKSALKNEVKKDKVGLIIISHGRIATETVNVVKELLGVKFPV
                     AIDMPLDEKPINIYNKAVELSKIIDQGKGILFLVDIGSLTNIGQIVNKRTNISTKTID
                     RVDLLMALEATRKVSMGEEELDEIFFSLLKDRMGYNYELEKHIDKSNAIITLCLTGEG
                     TAKYISKTLEEKYDNTKYYQMSALDENLFCKIENLKETNNILAIVGTINPKIPGINFI
                     PYNKELFKNLDIYLSKSKQQDDRPVKSYERMLDEDLVIFEPDIYFKKDLLEYVCSILI
                     NKEYVEKDYLDSVLHREEMLPTYSKGAIGVPHGDSSTVNSTRFVFVKLKNPIDWGVGN
                     VNFIFMPVFQANDKEIVKNVLEILKDAEFMNNANKCFDKDAFRRIIFDKFKHL"
     gene            32892..33338
                     /locus_tag="JAM15_07740"
     CDS             32892..33338
                     /locus_tag="JAM15_07740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAT6798139.1"
                     /translation="MNVDLISLGLESNDYESVIEELGSIMCKKEYVKETYINAVLERE
                     RTLPTGLDIGEMCVAIPHTDSKHVNESNVAVGILKNPVKFNSMIDPKDRLDVELVFLL
                     AVKNPDSQVKLLKDLMSVFQNIKLLKNIKNASTKEEVAKLLDFIEI"
     gene            33461..33763
                     /locus_tag="JAM15_07745"
     CDS             33461..33763
                     /locus_tag="JAM15_07745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAT6798140.1"
                     /translation="MKQFNVLSVCGSGTVTSSMVAGKLKEVLGNKGISITTTEARPTE
                     ALNLAQSGRFDFITFTSPLQTGDYGIPTINAFACLTGIGEEAFFEEVLTVIEGIDK"
     gene            33944..35350
                     /locus_tag="JAM15_07750"
     CDS             33944..35350
                     /locus_tag="JAM15_07750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HAT6798141.1"
                     /translation="MLEFMKSIIDTFGSAIIVPIIIFIIAKIFKVTTKKSFLSAVYAG
                     VALQGFTLILNSFTPIITPVINRMVESTGVNLPVFDVGWQATSLVAFSTSAGMIYLGL
                     GILLQTILFLIKWTDVFQPSDLWNNYSYMVWGAMVIGVTGNFPLGIACMVLLNLYSLL
                     ISELVAKRWSSYYRYPNCTIIAMHNVEASVFAVFADPIYNKLGLNKIKLNPKELEKKL
                     GFLGEPITLGLFLGMFIGILGNMTRINTMEAWGEIMKVGISTSAVMAIFPKVASMFAQ
                     AFAPITEAARKIMQKAGNREWYIAVNDAVGYGEPATLISGLILIPIMLVIAMVLPGNK
                     VLPVVDLLAIPYMVQGLVAIHNGNIPKVLVSGIIWFGLGLYVCTSTAPLFTDMATNIG
                     VAIPAGAMLITSFNILGKPLMGLVFFAFLSANPIYIGLSVVIYFVLWALFRKNKTSIL
                     DYLEKQALKNVEEEPVAV"
     gene            35694..36752
                     /locus_tag="JAM15_07755"
     CDS             35694..36752
                     /locus_tag="JAM15_07755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HAT6798142.1"
                     /translation="MGDKMRASVLYNVGDVRYEMVDIPEITDTQVLVNVKYVGICGSD
                     LPRSMVSGLSGNTKYPLILGHEFSGEVVKIGEKVNHINVGDRVAVAPLVPCRKCDYCN
                     EGNFGLCDDYNIIGTRVNGAFAEYVRVPEEHILKLPDTLDYETAAGIEPATIAYHGIS
                     KSNIRVGDSVVVLGCGPIGQFVIQWAKVFGASKIIAVDIFDEKLELSKLLGANYILNS
                     KEVNVIKEIKKITNGGADVVIETAGSRFTQEQSLFVAKKRGNIVFVGISHTELPLSAD
                     ATECILRGELTLKGSWNSYTSPYPGRAWTATLDFMGKGDIIFKPMISHKIGLNEVGDF
                     LSKMSKREINFNKILVEI"
     gene            36851..37537
                     /gene="araD"
                     /locus_tag="JAM15_07760"
     CDS             36851..37537
                     /gene="araD"
                     /locus_tag="JAM15_07760"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HAT6798143.1"
                     /translation="MLENLKEEVLKANLELPKKKLITYTWGNVSGIDREKGLVVIKPS
                     GVEYSNMTVEDMVVVDLEGNIVDGKLRPSSDTPTHLVLYKEFEELGGIVHTHSSWATI
                     WAQIGKSIPSCGTTHADYFYGSIPCTRKMTREEICNEYEKETGNVIIEEFMGRNPIHC
                     PGIIVNDHGPFTWGKDANEAVHNAVVLEEVAKMAYYTELMSPDNIMDKVLMNKHFSRK
                     HGKNAYYGQK"
     gene            37555..38202
                     /locus_tag="JAM15_07765"
     CDS             37555..38202
                     /locus_tag="JAM15_07765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HAT6798144.1"
                     /translation="MLDSLKGKIVEIAIKAEHYGLCKEKTGNFSIRDKDTGYILITPS
                     GIGREELKVEHICVLDLDGNVIEVEKGIKPSSEVLMHIEIYKTRENINAISHTHSLYA
                     TAFSVAKKPIIPIVYESVNYGGYVDIASYERPGTLKLAKSVSKLLIDTDACLLERHGL
                     TTVGNDLDEALLKSRYVEEVAEIYYRSLVLNQFKELEVVDVDEFKSWKYPEEIKF"
     gene            complement(38375..39742)
                     /locus_tag="JAM15_07770"
     CDS             complement(38375..39742)
                     /locus_tag="JAM15_07770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HAT6798145.1"
                     /translation="MNLIDILNKVDAFIWGPPLLVLLVGTGILLTVKLGVVQITKLPR
                     ALKLIFSAENKGSGDVSSFAALCTALAATVGTGNIVGVATAIKAGGPGALFWMWIAAF
                     FGMATKYSEGVLAIKYRTKDKNGQVSGGPMYYIVNGMGEKWRPLAIFFAISGILVALL
                     GIGTFTQVNSITDAINNSFGIDPRITGVVLAVFVALVVFGGLKSISNVATKIVPFMAV
                     IYVVICGIILISFWNKIPETFMLIIKSAFTPTAATGGFLGATMSLAIRNGIARGVFSN
                     ESGLGSAPIAAAAAKTEWPAEQGLISMTGTFIDTIIICTLTGFSLVISGVWCSDLNGA
                     VMTQAAFNGAIPTFGPILLTVSLTLFAFTTILGWSYYGERCFEFLFGVKGMNGYRTVF
                     VAMVLLGAFLKLEVVWIIADIVNGLMAIPNLIALLALSPIIVSETKKYFEHINSPENQ
                     IKKNA"
     regulatory      complement(39932..40020)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            40448..42568
                     /locus_tag="JAM15_07775"
     CDS             40448..42568
                     /locus_tag="JAM15_07775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010235392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAT6798146.1"
                     /translation="MGKILVLAEKPSVGRDIAKVLGSKNEKNGYIEGPKYVITWALGH
                     LVTLADPESYGERYKSWSLEDLPILPKHLKTVVIKKSGKQFNTVKSQMNRNDIDEIVI
                     ATDAGREGELVARWIIEKSQVKKPIKRLWISSSTDKAIKDGFAKLKSGKEYENLYYSA
                     IARAEADWIIGINATRALTTKYNAQLSCGRVQTPTLAMLLKREEEIRNFKPKEYYGLE
                     LIATKGNSDIKFIWNDKNNNSSTFSKEKIESTLKKVKGVDIKISEVNKSYKKKYSPAL
                     YDLTELQRDANKMFGFSAKETLSIMQKLYEHHKVLTYPRTDSRYLTSDIVGTLKDRIK
                     AVNISDYSKTCNKLLKSNIIANKSFVDNSKVTDHHAIIPTEQKVFMSDFSDKERKIYN
                     LVVKRFLAVLSPPFEYEQTTISATVEGEIFKAKGNKVINLGWKESYKDIEDEDEYESI
                     PNILEKDVLKVKGLKITSGKTNPPPYLNEGTLLTAMEKNGLGTVATRADIIEKLFNSF
                     LMEKKNKDIYITSKGRQLLDLVPVDLKTPELTASWEKKLLDISKGKLSKNTFINDMKD
                     YSKDIVLEVKNSDNKFKHDNLTKNRCPECGKFMLEVNGKKGKMLICEDRECNTRKTIS
                     QVTNSRCPNCHKKLELRGEGEGRIFTCSCGYREKLSSFNKRKQEEKQKASKKDVNQYL
                     KNQNKNQETFNNPFAEALAKLKNK"
     gene            42672..43925
                     /locus_tag="JAM15_07780"
     CDS             42672..43925
                     /locus_tag="JAM15_07780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliS"
                     /protein_id="HAT6798147.1"
                     /translation="MDLSGIFKYYCKECENTWNNSSVELFENIETYSKDSQKKREKEL
                     DKLLNTISVHLERYPSDAVLRKMWVKKGEVFLQKTLEKENIFKLEKMDVEDRKKFLDI
                     TKQFIRDARKFDDDLPIGDIMQAMRNVWISNALQLLFGKEVYYSKANFAYSMLYPYTD
                     NYLDNTNIDKNDKILFNNWLEKRLLGEHIKSKDYHESKVSQMIDYIESVYPREKFTEV
                     YESLLLIFKSQVNSLKQHGKENHLCKEDLLSISIEKGGSSVLVDGYLISGLMTKEEIE
                     FCIGYGFLLQISDDLQDIKEDLKYNHKTIITEMSKEGTLDKVVNKLINFTIKLIDSFK
                     INNKNKSVITMIKNDCLMLILFSVVYNAEFFSVGYIKEVEKFIPYTIDYSLEIEEKIK
                     EKFKNIDVLNNENEYKEMIDIICAE"
     gene            complement(44079..45140)
                     /gene="ytvI"
                     /locus_tag="JAM15_07785"
     CDS             complement(44079..45140)
                     /gene="ytvI"
                     /locus_tag="JAM15_07785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HAT6798148.1"
                     /translation="MDIQKQKNFIIKFTYVVLITSIVYIVLKFLLPLLMPFVISFIIA
                     SILRPIIRLITNNTNLNRTLISIVILLIFYGLCIFLLVSFGVKIFASVSDVFFRLPEI
                     YKSSIQPTLNTLFSKIDASTPNVNLALILGWDNISQSMMSLVASISTNALNAIASIAS
                     KTPAFMLKLIITLIASFFFTFDYQKIVNFILKQFPEKSQFMIINIKNSSINALLKLLK
                     AYAILLSVTFIELLIGLTILKVENAFTISVIIALVDILPVLGTGSILTPWMIISLING
                     NINLAIGLLILYIIITVVRQILEPKVVGHQIGLYPLITLMCMFVGAQLFGIAGLFGFP
                     IAATIIKNLHDNGIITAFK"
     gene            45414..46154
                     /locus_tag="JAM15_07790"
     CDS             45414..46154
                     /locus_tag="JAM15_07790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HAT6798149.1"
                     /translation="MKNFRDLGGNKTEDGRTVKKGLFYRSAKLSNLSENDIKILRELN
                     IKYIFDYRSDEEARKHPSTIISNIKNIRIPAMRELEESGGSFGSIEDMIDGLFEKDGA
                     FNMLNNSYYNLPINNPSYKKLVELIRDYSNLPILNHCTAGKDRTGVGSAIILMILGVS
                     RENIMKDYLKSNDFADKEIERFIEYKPKFKDIPKENLKYIFGVNEEYMKTAFRRIDEE
                     YISVEAYLYGEFNLNKEEIRKLRNQYLE"
     gene            46166..>46368
                     /locus_tag="JAM15_07795"
     CDS             46166..>46368
                     /locus_tag="JAM15_07795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAT6798150.1"
                     /translation="MSLNITARQINIIKILLNSKDTISGIALSQEIGCSSKTIQNEIK
                     DINKQLRNGKILSIRGVGYKLEG"
BASE COUNT        18183 a         5385 c         7219 g        15581 t
ORIGIN      
        1 agttgttaaa cataaaaaaa ccatttgtaa aaaacaaaaa aatcatttct ctaacaaaaa
       61 aaaccacaaa aaatataaaa aagtatggct agttaagtga ttaacaagta aaaattaaaa
      121 taaaaatcaa aaaaaattta tcaatgaaag tcagctaaaa tcctggaaga gagcattatt
      181 ttcgggaaaa cattttcttt tgtttcacaa aaaaagccac tttttggcat gcaacatgct
      241 ttatataaag tcaagaaaaa ctaaggtata agacaaaggc aattaggagg tgtaaatatg
      301 gagtttataa attttgtaag tgataaagtt atagacctta aaatggattg taaaacgaaa
      361 gaagatttct ttaaagaaat acataataaa gtttttgatt taggctttgt aaaagaagaa
      421 tttggagaaa aaatattagc aagagaaaat gtatttccaa caggtttaaa tttaggtgat
      481 tatggagtag caataccaca tacagatgca gaatatatta aagagcaatt tatatcagtc
      541 tgtactttta atgaaccagt agtatttagt tctatggaag accaagatga aaaagtacct
      601 gtaaatttgg ctttcatatt aggacttaat caaccacaca gtcaattatc tgtattaaca
      661 gaattaatgg gaattatgca aaataaagag ttagttgata agttgatgag ttctactgat
      721 aaagaagaag ttttaaggac actaaagtct ttataaaaat aaaaaagtac taaaaataaa
      781 aaatataaaa ataaaaatta ttaggaggaa ataaaaatga aaaaaatatt agtagcatgt
      841 ggagcaggaa tagcaacatc aacagtagtt tgtgacaagg tagagagatt agttaaggaa
      901 aataatatac aagcagaagt tatacaatgc aaaatagctg aatgtgcaac aaagcaagaa
      961 ggagcagatt taatagtatc aacaactata ctaccaacaa cttataatat accagcaata
     1021 aaagcaacag catatataac tggagtaaat acagcagcat tagataaaaa aatattagat
     1081 gctttaaaat aatcctatca tagatacatt gaaataatat tttataaaac agaaaaagga
     1141 ggatttataa atggataaat tattagcagt agtacaatac attttaaata tgggaccgac
     1201 agtaatacta ccaataacaa ttgtagtact aggaatgata tttagaatta agtttacaaa
     1261 agctttaaag tcaggtctta caattggtat aggatttgtg ggtataaact tagttgtaaa
     1321 cctattaaca tcaacactag ggccagcggc tcaaggaatg gttgaaagat tcggacttaa
     1381 tttaacagta atagatgttg gttggccaac aacagcatca gcaacatggg cttcaccagt
     1441 tgcaccaata ttaataccag tttgtttatt agtaaactta ctattattat acttcaataa
     1501 aacaaagata ttaaacgttg atatatggaa ttattggcac tttatagtag caggtgcagt
     1561 tggatatata gtaacaggaa gttatgtttg ggctatattc tgtgcaatac taatggagtt
     1621 attagtactg tttattgcag aaaagacagc aaaaaatgtt caggagtttt atgatttaga
     1681 aggtatagca ttaccaactg gttcaacagc ttcatttgct ccacttggat atttagtagg
     1741 taaatttgtt gaaaaaatac caggaataaa taaaatacaa gcagacccag actctataca
     1801 aaaaagattt ggtatatttg gagaaccaat gatgatgggg attatactag gtataatact
     1861 tggagcactt gcgggatatg atgtagcagg aatattcaat gtaggtatat caatgggtgc
     1921 agtaatgtta cttatgccta gaatggttag aatattaatg gaaggtttaa ttccaatttc
     1981 agaatcaata agagatttct tacaagcaaa atatggagac agagaacttt atataggtct
     2041 ggatgcagca gtagcaactg gacatccagc agttatatca acagctctta tacttgttcc
     2101 tataacgttg ttcttagcag ttatactacc aggaaacaaa gttttaccat ttggagactt
     2161 agcgacaata ccattttata tggcatttat agtgtgcttt agaaaaggta atatagttca
     2221 atcagttata acaggaacaa tagtaatagc tatatcactt tatatggcta caaactttgc
     2281 agatgttcat acacaattat tgcaacaagc aaatatgatg ccagaaggaa caacaatggt
     2341 tacaagtata gatacaggtg gaaacttgct aaaatgggga atattgaaat tatctcaatt
     2401 agtttcttca tttggaatat tctaatatgt agttaataga gattactctt ttttagtaaa
     2461 gtatgcgaaa atttaacatt tagcagctac taaaaaagag taatattttt tataaatttt
     2521 taaaaataca aaatacaaga ggaggagatt tatcgtgaaa gcagcagtat tacatggcac
     2581 aaatgatatg agatttgaag atatagaaat aaaaccatgt gaaagtgatg aagtaaaaat
     2641 aaaagttatg gcagcaggaa tatgtgggtc agatcctcca agagtattaa aacattggaa
     2701 atatccagtt ccagctatac caggacatga gttttctgga gtaattgctg aagttggtaa
     2761 ggatgtaaaa aatgtaaaag ttggagatag agtagttgca attcctttta taccttgtaa
     2821 tgaatgtgaa tattgtaaaa gaggattatt ttcattgtgt gatgaccatg gaatgttagg
     2881 agctaaaagt tttggagctt ttgcagagta tgtaaatata aaagctacaa atgtacttcc
     2941 aataggagat atggactttg aagatgctgc aatgatagag ccactagcag ttgctatgca
     3001 tggagtactt aatataggtg ttcaagttgg agacactgta gccgtaatgg gtagtggaac
     3061 aatggggcag ttggtaatac aaggacttaa aatagcagga gcaggaacaa ttatagcagt
     3121 tgatatatct gataataaat taagagaatc aaaggaatta ggggctgata taataatcaa
     3181 tgctaaagat attgacccag tagaaaaaat aaaagaactt actggtggaa aaggcgttga
     3241 catagctctt gaatgtgcag gttcaaaaat aactcaagaa caatgtttac ttataactaa
     3301 aaagaaaagt aagataggat ttttagggat agcatattca gatataactt tatcagaaga
     3361 agcatttgaa aatatattta gaaaagaact agaattaaaa ggtttttgga actcttattc
     3421 tgcaccattt ccaggacaag aatggactaa gggaatcaat ctagttaatg aaggaaagat
     3481 aaaattaaaa gaaatggtat ctcatagatt ctcacttgaa gatacttaca aagcatttga
     3541 aatgataaga gatagaaaag aagaatttaa caaaatatta attttaccac aaggggttga
     3601 aaaataatga aagcagtagt taaaactaaa ccaggctatg ataatgtaga agttttagaa
     3661 gtagaagaac caaaagctac aggagacaag gttaaaataa aagtagaata tagtggtata
     3721 tgtggttcag atatacattc atttaaaggt gaatatgcaa atataaaagc cccagtaaca
     3781 ttaggtcatg aattttctgg aattgttgta gaagtaggag aagatgttaa agatataaaa
     3841 gtaggagata gagttacatc agaaactact tttgcaactt gtgagaaatg tatatattgt
     3901 gaaactaaag attataactt atgcccaact agaaaaggta ttggtactca agtaaatgga
     3961 agttttgctg agtatgtact atcaagagaa gaaagcatac atgtacttcc tgaaaatgta
     4021 tcgttattat cagcagccct tacagagcca ctagcttgtt gtgttcatgc agctcttgaa
     4081 aagactacta tagaaagttc tgatacagtt ttaataatag gaccagggcc aattggttta
     4141 ttattagctc aagttgttaa atctcaaggt gctacagtta taatgtctgg tgttacaaaa
     4201 gataaggaaa gattagaaat agctaaaaat cttggagtag atagaactgt aaatgtaatg
     4261 gaagaaagtt tggcagatgt agtgaatgaa atgactgatg gaaatggagt aaacaaagga
     4321 tttgattgtt ctgggtttat gccagcagtt aacgaagcct taagactgct tagaaaaaaa
     4381 ggtactttcg tacaagttgg aatctttgct aaaaaattaa atgaaatgga ccaagaagca
     4441 ataatccaaa gagagttaca atatatagga agtagatctc aaaagccaag ttcttggatt
     4501 acagcattag atttaatggc aagtgggaaa gtaaatacag aagctttagt tactagaact
     4561 gttggtttag acgaatttaa agaaggtatt acagctttaa tgaacgggga agaaataaaa
     4621 gtagcagtaa aatcttaaaa aaacatttgt attattttaa aaaaaattgt aaaatctact
     4681 gtaggataaa aaaatgtaag gtcttaaaaa ataacaggag gaagaaagta tgagcactct
     4741 tagagatcat tctaataata ttagaaaaaa cataataaaa atggttgcag aagctaaaag
     4801 cggacatcca ggtggttcat tatcaatagc tgatatgttg acagtattat attttgataa
     4861 gatgaacgta tgtgcagaaa atccaaaaat ggctgataga gatagatttg ttctatcaaa
     4921 aggtcatgca gcaccagctt tatatgctac attagcagaa aaaggatttt tcccagaaga
     4981 agaattaata acactaagaa aatttggttc taagttacaa ggtcacccag acatgaaaaa
     5041 agtagcagga atcgatatgt ctactggttc tcttggtcaa gggctatctg cagcaaatgg
     5101 tatggcactt gcaggaaaat tagataacaa agactataca gtatatacta tattaggtga
     5161 tggagaaatc caagaaggtc aaatatggga agctgcaatg acagcatcac attacaaatt
     5221 agataattta attgcatttg ttgacttaaa tggattacaa atagatggtt ctaatgaaga
     5281 agtaatgaat gtaaatccag tagatgacaa attcaaatct tttggatgga atgtaatagt
     5341 aataaatgga cattcttttg aagaaatagg aaatgcagtt gatgaagcta aaaaagttac
     5401 aggaaaacca actgtaataa tagctaaaac agtaaaaggt aaaggtgttt catttatgga
     5461 aaataatgct gcatggcatg gaacagctcc aaatgcagaa caagcagagc aagcattgaa
     5521 agatttagaa ggaggtctat aggaatggga atagcaacta gagaagctta cggacaagtg
     5581 ttaaaagaac ttgcagaaaa taaagatata gtagtattag atgcagattt aggaaaagct
     5641 acaaaaagta tatcatttaa agaagttgcc ccagatagat tttttgacat ggggatagca
     5701 gaaggtgaca tgattggtac agcagcaggt cttgctactt gtggaaaaat accttttgcg
     5761 agtacttttg caatatttgc agcaggaaga ggctatgagc aaataagaaa ctctgtagca
     5821 tatccaaatt taaatgtaaa aatagcagct actcatgcag gtgtaacagt aggtgaagat
     5881 ggtggtagcc atcaagctat agaggatata tctctaatga gaggtatacc aaatatggtt
     5941 gtattaaatc cagcagatgc tttagaagca agacaagcta ttcttgcatc tattgattat
     6001 aatggacctg tttatataag attaggtaga gctgcaactc ctgatgtaaa cagtgaaaat
     6061 tataaatttg aaataggaaa aggaactgtt ttaagagaag gttctgacat aacagtaata
     6121 gctacaggaa taatggtagc aaaagcctta gaagcagcag aagaacttgc taaagaaggt
     6181 ataaatgtag aagttgttaa tatatctaca ataaaaccat tagatgaagc attaataaaa
     6241 gaaactgcta agaaaactgg aaaagtagtt acagcagagg agcacagtat aataggtggt
     6301 ttaggttcag ctgtatgtga agctttagca gaaactaaag atgtagtagt tagaagaatt
     6361 ggtgttaaag atgtatttgg tcaatcaggt acaccagctg atttattaaa acactatggt
     6421 ttaactacag aagatatagt aaaaaatata aaagagttgt tatagatata aatatatcta
     6481 aataacaaat tgatttgaca taagtcaatt aaagctgtct taaaaataga aagaaatttc
     6541 tacaatggga cagctttatt tttacaatac tttattttta tgataattat aaaatagtct
     6601 gaaagtaatc aaaaaaatta taaaaagagg tgctatttaa tgaaaatatc tattggatgt
     6661 gaccatggtg gttatgaatt aaaggaatat ataaaggaaa atttaataaa taaaggtata
     6721 gaagttgaag atgtgggtac aaattcaaaa gaaagtgtag attttccaat atatgcaaaa
     6781 aaggtaagtc aaaatgttca aagtaaaaaa tctgatttag gcatactttg ttgtggaaca
     6841 ggaataggca tgtctattgc agcaaataag tttaaaggaa tcagagcagc tgttgtttct
     6901 gactgttttt cagctaaggc aactagagaa cacaataata caaatgtact ttgtttagga
     6961 gaaagagtta ttgggaaagg attagcaatg agaattgttg aagaatggtt aaattcaagt
     7021 tataatggag aaagacatgc aagaagatta caaatgattg atgatataga aaaagaaaat
     7081 ttataaatat ataaaatata taatttataa caagggggag cgttatgtct attatttgtg
     7141 cttcaataat gtgtgcagac caaatgaagt taaaagagga attagaagct cttgaagaag
     7201 caggtgtaaa attacttcat tgtgatgtta tggatggaat atttgttaaa aacttggcta
     7261 tgggaccaga gttattaaaa tcaataagtg aaaatacaac aataccttta gacatacact
     7321 tagccacaga aactccagat aaatatattg atatgatgtc ttatataaag ccaaaatata
     7381 tttcttttca tgtagaatca agtacaaatg taaaagctga tatacaaaag ttaagaaatt
     7441 atggtatagg gccagtgtta gcaataagcc ctcaaacaag tgtggataaa atagaagaat
     7501 atataagttt agttgagggt atcttagtaa tgacagtaaa tccagggttt gcaggtcaaa
     7561 agtttaatct ttctgtattg gataagttgg ataaacttac agagatacta aaagattatg
     7621 ataatcctcc atttatagag gttgatggaa atataaataa ggatactatt aaacttatga
     7681 atggtaaaaa agtagatata tatgttgttg gtacttcagc tttatttaat gataagcctc
     7741 caatttcata taaagataaa atagaagaac taaaagaaag tataaagtaa ccatgtaata
     7801 aaattataat atgtttctgt ttaatagtaa aaatttaggt ggaaacaaga aattttataa
     7861 tatttaataa aaattttggt tgagtaagga gaatttttta tgggagacct atataaacta
     7921 caaaatggta ctgatattag aggaatagcg tatgaaaatg attctaaaga agttaaccta
     7981 actgtagaag aagtaaaaaa aatagctaaa gcgtttcata tttggctaaa agaaaagact
     8041 aagaaagata aagtaactgt tgccatagga actgattcta ggataacagg aagccaattt
     8101 agaagtactg ttattgaaac tttaactaat gatgattgta atgtaattga ttgtgagatt
     8161 gccacaactc cagctatgtt tatgacaact attatggatg gatacaattc tgatggggcg
     8221 attatgatta cagcaagtca cttaccttat tactataatg gtttaaagtt tttcacagaa
     8281 agtggaggtt tagaaaaaac tgatataaaa gagatgttgg atatagctgt taaaaatgat
     8341 agtgtagact atgaggaagt aaataaaaaa ggtgaagtta tagtaaaaaa tttaatagaa
     8401 gattattcta atttattgat agataaaatt agaaaaggtg taaattcaag taaaaattat
     8461 gaaaagcctt tttctgggct taagatattg gttgatgcag gaaatggagc tggtggattc
     8521 tttgctgaaa aagttttaca catactggga gcagatacga caggcagtca gtttttgaac
     8581 ccagatggta tgttcccaaa tcatatacct aatcccgaaa acaaagaagc aatggaaagc
     8641 atatgtaaag ctgtgttgga taataatagc gacctaggaa taatctttga tacagatgta
     8701 gacagagctg ctattgtagg taaaaatggc aatccaataa ataaaaatgc tcttatagct
     8761 gttatatcat caatagtatt agaagaacat ccaaaaacag ctatagtaac agattcaatt
     8821 acttctgaag gacttgctaa atttataaat gaattacaag gaagacatca tagatttaaa
     8881 agaggatata aaaatgtaat aaatgaagct ataagattga atagtgaagg tgaagagtgc
     8941 catttagcta tagaaacgtc tggacatgct gctttaaaag aaaattattt cttagatgat
     9001 ggggcatatt taatagctaa aattttaata aaagtagcaa agctatcctt ggaaggaaag
     9061 actatagaag aattgataga aaaccttgaa gaagctcaag aagagaaaga agttagaata
     9121 ggcattaaca aagaagattt tagaccatat gcagaggata tattaaaaga tttagattct
     9181 catgttaaga gtattgatgg atggtctgta gcaccaaata attttgaagg aataagagtt
     9241 aattgtgatg aatcaaatgg agatggatgg tttttactta gaatatcact acatgaacca
     9301 ttactagctt taaatattga atcaaataaa attggtggag cagaacaaat ttattctaag
     9361 ttaaaacttt tcttagaaaa atatgattta aaaggtcttt agggtaaata gaaagaatat
     9421 atttatatta aagaacaaat gtaaatttgt acctaagatt acaaatatta caaaattgta
     9481 atcttaggta acagagatgt aactgattat ggaaacacta tgtgatatta tagatacaga
     9541 gagatgaaat atgtgatgaa ttatagagaa atataattta aaatgtatta atatcacacc
     9601 aaaaaggtat aatcaaaaaa tatgtaaata taaaccccaa catttagaaa aagacctcta
     9661 aggaggtttt tttcttgttt aaataactta aaatatattt ttatattaat atatcaatta
     9721 actcttctaa aagtaagcat taccttaaat aaatcagcat ctataattat ttccatgtgt
     9781 gcattttcta attcaattat attttgagca attgataaac caagaccaga gccatctgtt
     9841 tttctagata tatcacccct tctaaatctt tctattaact cttctggctt tagatttagt
     9901 ttatcatttg aaatattttt aaacgttaat attatatttt cttcctttat aaacatatct
     9961 atatagaccc tagtgttagg catagagtat tttagtatat tgcaaattag attctcaaaa
    10021 actctccaag tttttttacc atctatcatg gtaaaaacag catattcagg tgtttctatt
    10081 ataaaatcta aactgctatt tttaattttg tcttcaaact ctacaatact ctgaattaaa
    10141 agttctctta tatcggtttt tgttatatta aattctacat ctccactact tagcttagat
    10201 gcttcaaata tgtcatctat taataatttt aatctttgtg attttttatc taaaatattt
    10261 atatagtcat ttatagtctc tctgtcaaag tcattatttt ttaacatatc aacatagctt
    10321 aatatagatg taagtggagt ttttaagtca tgagatacgt ttgtgataag ctctgccttc
    10381 atcctttcat tttttatatt agcatctaca gcagtttcaa gaccacctgt tatattattt
    10441 atacttttgg ctaaagtaga tatttcatca tctcctataa cttctaattt atactttaaa
    10501 ttgccatttt ctatattttt tatatttttt gatatgttat ttatgtaatt aaacttaaca
    10561 gataaaaagt tgtatatata aaaatgaaaa actgtgttta caagtgtaaa taaaattact
    10621 atagctattg cctcagcata atatatatac ataaagaata tcaaaacaag atattggata
    10681 atagcttgta caactataga tattaaaaat actatagcta attttttatt tatagttttt
    10741 ttattataca tactaagtaa gtttgaaaag aatacatatg ttatagacat atcttttaga
    10801 ttatagttat tatatttaat gttttcatat attatataga ctatagatat aattataaaa
    10861 ttgtagatta ttaaattagt gttgtaaaat attttattac ttgtaaatgc atgaaacctt
    10921 aaggttaata gtatcaaaat taatataagt gtaagttcta tttttacctt agaaaaaagg
    10981 cttatgacat tttctaagaa tttaacttta gtctgtttat tttttttata caatgtaaaa
    11041 catagtatag tcaataaaaa acttgataat ataataccta tgcagacaaa ctctaattct
    11101 acttttgaca aatgtacagg agtaccgaaa aaataaaaat aagggagagc aaactcttta
    11161 taataataat taatattata agaaaagtta ttattcaaat cataaactgc ttcaaataat
    11221 atagaaacta atagaaacag taataataat aaaataaatt ttgctttaga atcattaata
    11281 attaagtttt tcaattttgt aaccaatgcc ccacaccacc tttaaatatt ttggttcttt
    11341 tggattaatt tcaatttttt ctctaattct tctaatatga acagcaataa ttctctcaca
    11401 actataagca tcttcattcc agacattttc ataaatttca cgggaagaga aaattttacc
    11461 ttttcgtgac ataagaagtg taagtatttt atattcaagt ggtgtcattt taatttcctc
    11521 accatctaaa gaaactattt ttgtatctgt atttagctct aggccaccac tttttagaat
    11581 ataattagta tcatttgagt tatttgtatt actaaaatca cctaaattta tataccttct
    11641 aagttgagat tttactcgag cagtaagttc tagtggatta aatggtttag ttatatagtc
    11701 atcagcaccc atattaagac ctataatttt gtccatatct tctgattttg cagataagag
    11761 aattattggt atattccttt tttctcttat tttaagtgta gttttaagcc catctaaatt
    11821 gggcatcatt acatccatta ttattaactt aatatcattt tcgattagta tgtccaatgc
    11881 ttcaagtcca tcatatgcct ttaaaacatt aaagttatca ggtctcaaat agaactctat
    11941 agcatcaact atctctctat catcatctac aaccaatata ttttgattca atttattaac
    12001 ccccttgaaa ttttattttt aaccaatttt tattttatac caaaaagagg tattagaaaa
    12061 cagtaagccc gttcattatg aaataaaaac tagtactttt aatatattgt caatgcatat
    12121 agtaaattta aaagtataga cgcccatatt aatctgaagg taaaagttta tgaaaatatc
    12181 tagggtaatc tatcacactc cttatgttat tttgggttta ttaatttttt aggtttaaac
    12241 atatattaac aaatataaat aacaaatgag tttcataatt attaagaatt tataacaaat
    12301 atttatttta atgtagttta atataaatag gtagtttaat gtagatatgt ataaagtatt
    12361 taataaggct tataggtttt aatgatgata tctttatata ttttaagaga tgatgaaatt
    12421 agatatgggt aatagttgaa tgagaaaaag tagtatagca caaaaagtgc tatatcacaa
    12481 aatctcaaat aatttccttc ttataactta aattaaaaga ataaatattt cttataaatt
    12541 aggtgtatga agtatagcag gaacatcttt attatttaat aacttatcaa atgatttatg
    12601 gtcagactta tagccaatac cttctctata ttctaattca tcaacaattt tgtattgttg
    12661 acaggcattt ttaacctttt catagtcttc agtagaatga gctttataaa ctatcttatt
    12721 attaaaagtt attttatcag caaatttagg ttttacaaaa tatttagcat cttttatttt
    12781 accaacatta tataaatttt ggataacaga accatttttt aaatgttgta aatggtcatc
    12841 taacttataa gtatgtgcta tatgagttac atttttaaat ttttcttcaa atgtaagagc
    12901 aattttttcc atgtaattga agtcagtatt accatttgta tttgtttctg gtaataatat
    12961 tatattttcc cttattacac caaggctatt aagagaagct aaaaattctc tatttctata
    13021 ttctgatttt tgtatatttg ttaggttttc atatttttta tatttatcaa agacggatat
    13081 accacatcca gtagatacta aaactacaaa tacatgattt tttcctcttt cttttatagc
    13141 attaacaata gcactcccag cccacaacac ttcatcatct tgatgctgaa catagaagac
    13201 aacataatct ttaaattttt tatgactata attcacatag ctactaaaac cggttaaaat
    13261 caagcataaa actagaataa tagatagaat ttcatattta tttatagtaa attttttatt
    13321 cttaaatgtc atttaatcat ctcctgaaaa gttgtcttag ttatattatc aaacaaagta
    13381 ctaaaaatta ttttttaaat gctgaaaaat atagagtaga ttaatggaat aaaatttttt
    13441 ttattagttt aaaataaaga aaacatttat gtataagact aatcaaaata ttaataattg
    13501 ataggaattg agatttaaag ggattgtaca tttattcggg attcatttta atagaatttt
    13561 actttagtac ttagaataaa agtaataact ttttaaattt aaagagtaca catatatatt
    13621 tgtgtactcc ttgatgatat gattgcttat ttactacaaa aacagagtct ttttaaacct
    13681 aaaatatttg atgcaccagc tatcgtagtt ccataatagt aaactggttt gttaagtgat
    13741 agaaaattta taattgagtt attacataat gtacttcctg tgcaaatcac taaatcagcc
    13801 caagatatta catcttcata atctcgtata ccatcttcaa tcttaacatt atattgaata
    13861 gtatccacaa attcaggatt taaatctaat actcttgttt cgaaaaagtc cttaatatta
    13921 tcaattatgg ctggttgata tcctataatt gctacttttg gattaccaaa ttccattttt
    13981 ataaactcag gaaatttttt tgcacatacc tcgggctcgt tatttttaca atgaatggtt
    14041 ctatccgtct tgcctaagta tttcataact gcatttaatg atgctataaa aagacttcta
    14101 tcatgaggat tgtcatgtaa atctaatgat aatatgtctt ttaaagaacc ttcaaatgta
    14161 gatggagtag aagtaaatgc ttgtccttta gctcctttaa agtcagcttc aagcattatt
    14221 tctttaccaa ctataattgg gaaatcttta cgcttagtat ttccaattgc ttcttttgaa
    14281 gatagagatt tggacacaat acttatcata tccatattta aattatattt atcgacttgt
    14341 actaatagat aatctctcaa aatatcaaat atattcatag aaaaaagatt ctcctttatt
    14401 ttttatttct tcatttaaat caaaaatatg atttattttt ccattgttca ttattcctat
    14461 cttatgagca aaaaacattg cttcagaaat atcatgagta acatgaatca ctgttggttt
    14521 gtattttatg tagacatcct tcaaaatttt gcttatatgt ttttttgtaa tataatccaa
    14581 tgaactcata ggttcatcta aaagtaatat atcaggttca gctattaagg cacgtgcaaa
    14641 agcaactcgt tgcttttcgc ctccacttaa atttttagga tacctatttt ttatatcttc
    14701 tatctgcatt aatttagaca agtggttagc cttaagaatc tgttcatcta taggtatttt
    14761 tcttaattta agtggaaacc ttatattatc ttcaacattc atatttggaa ataattcaaa
    14821 attttgatat acaaatccta tatttctatt ttctggaggt aagtttgata ttaaattttc
    14881 tttatatgat acatttcctt tagcagatgg atatcttcct gctaatgttt ctaggaatag
    14941 agttttacct gacccactag ctcctaataa aacaaagtat tcatgattat taatatttaa
    15001 actattttct tgtaatttaa aattaggtaa atcaagagat aaatttttta tttttaacat
    15061 attaattctt atcaacctct ctattaaaaa atatctcaaa aagcatcaag catgtaagtg
    15121 agataaatat caaaattaca gctattccga ttgcaatgtc tatatcacca gtagacatat
    15181 ttaaatatat agatgtagga ataatttcag ttttcatacg tgtagaacct actatcatag
    15241 ctactgcacc aaattcacca agtgctcttg accaagtcat tacagttgca gatatgattc
    15301 cagtttttag atttggaaga attataaatc taaatgcttc ccaactatta catccaaggg
    15361 tacgtgcaac aaatatcatc ttttcattac tttcatttag tgaagtgtga agtattttaa
    15421 tagtaagtgg aagatttaca aatacttgtg ctaaaactat accttgcttt gtaaatataa
    15481 aatcaagctt aaaaatctta taaatggaat ctccaatccc cattcttcca aacaaaagta
    15541 aaagagcaat tcctgatact aagtgtggaa gagacatagg gagatttatt atctgtataa
    15601 tcagtttttt aaatggtaat ttagtaatat gtaaaaaata tgctactgga atagctaata
    15661 aaaggcatac tatagtagat attaaagatg ttttaatact aagtgttatt gcatactgta
    15721 cttccacgga ttttaagcat ataggaacat aacttatccc tttaatgatt aacataagaa
    15781 gtggtgatac aataaacaaa aagactatag caaaaaatcc agtaagtagt gtagtaaaaa
    15841 atttattttt caagtttaat cactacttaa caggttcaaa accatatttt ttaaatatct
    15901 gtttagcttc atctgactct atataattta taaatttatt agctaaatct tttttatcac
    15961 tatagtttac gattcctgct gatatgagtt ggtctatatt tttatctttg gcaatttcta
    16021 taacttctac atcttcattg ccaaagaccg aatcttttgt ggctattgta gcatcagctt
    16081 tacttgatgt taactgtaca atcatttcat ttacagttgc agctgtagag acaacattat
    16141 catttataga ttttaaatta tttttttcaa gtattttttg tgtagtctta cctatagcat
    16201 tagactcttt gtctcccaaa ataagtttaa ctccatcttt atttaagtct tccaattttt
    16261 gaatattagc tggatttcct ttaggtacaa ctattgcagg tgtatgatgt gcaaccgttt
    16321 tatgttcacc tacaagttct ttttcaaagg cctttgaata aattggttca gaaccaacaa
    16381 taaatacgtc tcctttgtga cttgtctcaa tttgagctat tagctgtgca gaacctgcat
    16441 agctatattc aactttgaca ttattttctt tctcaaattt ttttgctatt tcatccattg
    16501 gtttctttaa acctgcccct gaatagacaa aaagagtctc tttttctttt gaatcatcag
    16561 ctgttgtcac tttagtatta gattcatcat tagctttgtt ttctttagaa ttacatgcag
    16621 taatacttaa tgaaataatc atagctaaag ctagtactga aagtttttta aacataagat
    16681 attccccctt agtaaattag tgtaaattct tttttagtat atcatactaa gaaaacgatg
    16741 tctaagtttt tgttatgttt tataatgttt tgttatgttt tattatgtat agttaagaaa
    16801 aaatctattt ataatgtcat ttccataggt agttatttta tttttaattt ttattaatac
    16861 tttaaagtat tttaaattta aaaacttaaa ttaaattaac ttattgtaga ttttttactt
    16921 tttaactaat tttatattta ttatatttca gtgaaaaaat agaacattga aacatataga
    16981 tatgttttaa ttgctttata ttaacaaatt actaaaagtg ttatatcaga attgaataca
    17041 aaagaaagag tatgtattta tgagatagtt gaaaattttg atgtgccaca actaaaatta
    17101 ttatattact atatattcta attaaaagag tacttgtagg tttaagtaca tactttataa
    17161 atatattttt gtcagattta ttttataaaa agtatttaga ctaagtatta tttttaagta
    17221 ttttcttgtt gaagttattt tttccttttt tacaaaatgc gtaaataaaa aaaagactct
    17281 taaaagagtc tttccgaaaa atctatatat tataatatag ttatattttc tgcttgagga
    17341 cctctagcgc ctttaactat atcaaagctt actttttgac cttcttctaa tgatttaaat
    17401 cctgaagttt gtatagctga gaaatgagca aatacgtcat ctccactttc cattgatata
    17461 aatccaaatc ctttttcatt attaaaccat tttactattc cattattcat taaaaatact
    17521 cctattaacc tatatcaaga tatacttgat ttacttgtgt attaccacaa atactattat
    17581 atcatagatt aacataaatg tctatttaat tataattttt agttaacatt tttatttatt
    17641 cttaatatga aaataaattt aaacatttta tattaccaat atattaatgt aaatgtagat
    17701 aaaactaaaa agggttttct agaagaaaat ctgtctaatt atacttactt accaatacca
    17761 tcacttgatg caagcaagat tccacaactt tttctccgta ctctaatata aaatcatcta
    17821 actgtgtatc tataaaatca caataatcat atgaactatc aatataagca gttaacatat
    17881 gtgtacattt atccatttta tctctaaaca taatgtattt atccccctaa aaaactttca
    17941 tgaaaaacaa aaagaaaata tctttttggc aactggctga cataacttat tttataagcg
    18001 ttagtcccta tagctttgcg tcactaaatt tctctagttt tgccgattta gttttattct
    18061 acagattaat aatacaatag aattagctat tattcaacat atctagctga aaaattaata
    18121 aatttatata tgaacgttaa attatttgaa aaaataaaaa gcccctctgt caggagtgac
    18181 ttaaaaattg aatttaagtt tgtatttaaa acacattttt aataatgcaa aaactaatca
    18241 aaaataaaca attcatcaat aggtgtatct actatttttg atatatctat tgctaatttc
    18301 aaagaaggat tatactttcc tgcttctaaa cgcataatgg tttctcttct aactcctact
    18361 ttttctgcta attgttcttg agttaattct tttaattgtc tatatttttt taggttacaa
    18421 atgaatttgg gcatattatt tttcctctaa aatataaagt tttatagcat aaacatttaa
    18481 agtgattgca tatgtaattg atagtaaaac acacattaat tctacattcc tagacactat
    18541 agtaatacac cataaaatga ataattctat aatagcaagc tgtcctgtaa atgccatagc
    18601 tgctttttca tcttgtacat acctttcatc tgctttatca ccatttattt ttgctataat
    18661 aaagtttgag aaaaaagcaa aaaatccaat atatgtaaga tcagcaacat tgccagatga
    18721 aaaatatcta agacttaaaa atccaaggaa accacaaaaa cccataaaaa attttttctg
    18781 aatcattttt tatcctcctt agtaatttta aaagagatat atttgtatct ttataataca
    18841 aatatatctc ttttatattc ttttgtcaat agaaaatcag tattatacaa tatttgtact
    18901 gcaccataat tgttagagca aaaatctaac gcttgagatg tttatgtatg actaaatatg
    18961 attttaattt caaattaaaa gtagctaaat tttatttgaa tagataagga agagatattt
    19021 taatagtaaa acaatatgga gtttatgacc attctcaagt tgaaagatgg gttaatatat
    19081 taggagaggg tgcactaaaa ataaaaaaat tttctatact atatggttca agttagatgt
    19141 tataaactat atgatgataa ctaaatatag tgtacaataa atcgctaagt attttggaat
    19201 aaacaatatc acagttatag caacatgaaa acaaaaattt ttacatagtg gtgttgatgc
    19261 cttttccaaa atgaaaggaa gaccataatg aataaaaaca aaaacactaa agaaaaaata
    19321 aattaacaag agaacaagaa ttagaatatg aaaataaatt tttaaaagat gagcttgagt
    19381 ttttaaaaaa gatgtgtgcc tcagggaagc cacattaaaa atagtggtat cattattaat
    19441 caaaagaaag ttagatgtat tatcaaaaaa ttagaactta aatgcatagc attttttcat
    19501 aaatcacata aatataactc ctataaaggt acaattggaa aagtaaaaaa taataaaata
    19561 aatagaagat ttaaaacatc aatagcatat cagaaaataa caaatgatat gctagaattt
    19621 ataaaatata tctaatgata aaaatggaaa atcaattata aaaaaggcat atctcgattc
    19681 attttttgtt atatagtcaa ataagaatac tatagatgaa agatacgatt ttgcagatgt
    19741 attaagtaag tattctgatg tttttggttg atacacatgc aataaagaag ttgtgtttgc
    19801 agataaatta gcaaaactat agtataagtt gcaacaataa agagaatgaa aattatcata
    19861 ctaaagcata agacatgtta caattttatt agataggaca ttaacataca ctaaagtact
    19921 ttttattata aagagtactt atttttttga aattcattaa tgtataaact atcaagaata
    19981 ttactcaaca taatttaaaa acaacttgaa taggtatttt taaattatgt gatataataa
    20041 aaaatagaag tgtatgccaa tacacttctg tagttataac taagcattct attcttgagg
    20101 agtacttttt tcatttctcc aaacaagatt gtttatttca tcagtaatta ttaaatcaaa
    20161 tttattgtat ttaagtattc gatttattat ttaaaagttt tattacaata tttattttgt
    20221 tttgatcgtt cgttatgtct attaaatttc cataatcatt ttttaattta tctagaccac
    20281 ttttgcttat ttctccttct ggaagtatgc ttaattctag atatttttca tgaccaggag
    20341 atgacattaa cagatatgaa ccattataag gcatccctaa attttctatt ttatctgcta
    20401 atgggtcatc tttaaaaccc ccatttatta ttatttttcc atctttcttt acccatgata
    20461 tcattcctcc atcagtatac ttggattcat cagcatagta actaagagat gcacttttta
    20521 ttgcacttat atcagcttca agtttagcta tctttgcttt ttctatattt taccatatat
    20581 agacaaaaaa atcactttct atgacaaata tactattatt ttacaattta tagaaatgat
    20641 ttaaaatgac atttcttgtt agaaaagata taagcaatgg attaaaataa agaaaactac
    20701 agtcatatca atgtcaataa tattatttaa aagcagatga aaataaaaag aggacccaga
    20761 aaataatgtc tatttaatta tacttactta ccaataccat aacttgatat aaacaagatt
    20821 atactacatt ttttttatgc tctagtataa aatcatctaa ctgtgtatct ataaaatcaa
    20881 aataattata tgaattatca gtataataag tcaaaatatg tatacatgaa tacatatttt
    20941 taaaagatat atattattac atacctaaaa aactttcata aaaacaaaaa taaaatatgc
    21001 ttttagtaac ttgttaacat aacttataat ttattttata agcattagcc tatatagctt
    21061 tgtgctacta aatttctttg attctaacga tttagtgcta ttctacaact aaaataatac
    21121 aatagagcta tttattgttt ggtagcattg tttgcaaatt aaacaaattt atatatatga
    21181 atattatttt acgtttaaaa aaacagacta aatatgtaga atatttggta aaacttacct
    21241 ctagtttttg tcttaaaaag ctcctattat taatttaagt tagaagaatt aaggaagtga
    21301 cataaattga aagaagaaat attaatagaa aaattattaa gagcagaatt aatagtaatg
    21361 gagtatttat gtaaaaaaga cactctaatg cctaaaaaag aaattgtaaa agaaataaaa
    21421 cagatttatg gatggcataa aagtacaata aaaatactac taaaaaggct agttgctaaa
    21481 aggtatttgg ctagatatat tataaatttt caatatcatt ataaaataat aatagataat
    21541 aaagaatatt atacttttaa gaaaaaggta ctaaaatcta gtaaaagcat aaaaataatg
    21601 cgttcactta ccactacaca taaaaatgta agtaaagaga agttagacct attagatgag
    21661 tattatagaa acttaaaaga atgatatagt aaaaatcgaa tgtaattatt taccttaatt
    21721 cttttgtttg taaaacttta ttgatataga atttaacata tacataaatt ggtaaaggga
    21781 tgtatactat gaaaattagt aaattaccag aagcggaatt aaaagttatg agatatattt
    21841 gggaatcaga aaaggtatta atatcaagag aaatcaccaa gtctatggaa caaaaatatg
    21901 aatggaaaga tacaactata tttacagtat taaaaagatt actaaagaat agagttttta
    21961 gaaacggaga aaatagataa gcgtacacac tataatgtat tagtaaaaga aaaataatat
    22021 cagagatttt aaacaaaaga atttttaaag aatacacata aaaattcaat attaagttta
    22081 atgtcagcac tatgtagtaa ggatgatgaa gtagatggtg atattttaaa tttattagaa
    22141 gaatatttta agaatttaaa ataagaaaat gacagctaga tacataataa ataaaatgaa
    22201 ggtatgaaat tataactttt tctacattca ttttgtttat tattctgaac atgttaaaaa
    22261 aatgaaataa gtttgtattt tatttatata aattttaata gaatatgtac agtatatagt
    22321 agatagaatg tataaaaata gaatttaaat aagtagctat tattgcagtg aaataaatgt
    22381 ttctaagtat atttgggtgg aagaatggtg gaagaaaatt agtgaaatgt aattcttcca
    22441 ccattcttcc acccaaaaaa taaaaactgt tcaataagaa ttaatataca ttaattcagt
    22501 tgaatccaat caaaatactt aaataaaagt aatctgaaaa taacataatt caaatcaatt
    22561 tattcaaata aatctcaatt tatcttaaat cttaagaaat atttaagaat taggataata
    22621 ttttcttaag atttatattt tattatatag ttataaggga aagttacaaa aatgtaagcc
    22681 aaagtaatat aacaatttag tcattgttga gaaagtaagt gaaagatatt gtataatata
    22741 gataagtatt attatacaat agaggaagtg aaaatatgta caatatatta gtagtagacg
    22801 atgataaaga aattgttgat tcaatagaaa tatatcttaa atcagaagga tttaaaatat
    22861 ataaagcata tgatggaatg aaagctttgg aaataataac agagaatgac attcatctaa
    22921 tactaatgga tataatgatg cctaaattag atggaatcaa agcaactgta aaaatacgag
    22981 aagaaagaaa tattccaata attttaattt cagcaaaaag tgaagataca gataaaataa
    23041 taggattaaa tattggagct gatgattata taacaaagcc atttaatcta ttagagctta
    23101 tagctagggt taaatcaaac ttaagacgat atgtaacttt aggtaattat gaagatacat
    23161 gtaaagaaat tttaaaaagt ggagctttgg agttaaatac actaacaaaa gaagttaaaa
    23221 ttgatggtga aaacataaaa atgactccaa ttgagtataa aataattgaa cttcttttag
    23281 aaaataaagg acgagttttc tcaatagatg agatatacga aaaagtatgg aatgaggaaa
    23341 gttttaattc agaaaataca gtagcagtac atatcagacg aataagagaa aagattgaaa
    23401 taaatccaaa agaaccaaga tttttaaagg tggtgtgggg agttggttat aagattgaaa
    23461 aattttagtg gaaaaattat aaaagaaaag agtttaatat ttaattgcat tttgatttta
    23521 gtcattttta catttacaca aatgttagga attttaatat gttttaattt tttctctgag
    23581 agtttaattt actctatggg gattatgctt ttcttaaact ttattttata taaaatactg
    23641 acaatgtaga tgaggtgggc aacttggaaa aatatagagc attaaaatta gtttcattaa
    23701 tcataatatc tatctcattt ccattaacta tattgttggc tacaatagga cttgctgagc
    23761 ctaaatacaa tatacaaaaa acttctacaa agagtgggat ttttaatata tctaatgatt
    23821 tttatgatag taatatattt gatgaaggaa cagtggcaag cttattatct aattttaaga
    23881 tatctgtgga tagtcagtta actagtgaag aaaaaagtaa actccaaaca aaaagtaaaa
    23941 gtatagattt aagtagtaat gattctgagt atgataaaat catgattaat gaacaagctt
    24001 ctgaagaata tttaagttat ctaaaaaatg taaaagtgta tgttattaat acatatacag
    24061 gcgtatttta tacaaataca tcatatggta atttagatga ttttaaacaa aaaactaaga
    24121 gctattgtaa tatagagata ataaataatg taggaaagag ctcgtatatt aaaacaataa
    24181 atggagaaaa atttgaactg aataatctga gtatggaact aaatggagta gatgaagcct
    24241 ttgaggcata tgtctctttt ccagaagagc caactataga agatggaata gtatacacta
    24301 attttcaaat atttaaacaa gctacagaaa aagtaagatt attttttgta gcttgtttaa
    24361 gtttagcaat tgtgtgttta ttatctatca ttttatatag cagaataaaa ggtgaagttt
    24421 taaaaagaaa taatgtattt ttactaatat acagtaagat acctatggaa tttaatgtaa
    24481 tactagtatt tatttcaatt gcaattttaa ctatgtatgc tcttgctgta tcttatcata
    24541 ttgatgtaat tgtattagtt tctttatctt tactgatagt atcaaataat atatttttta
    24601 taaatgtgca attgagttat ttagaaaata aaatgtgtat atttaagaca agtattatag
    24661 taagagtgat tttatggtta ataaaaacta taagggaggt cagtaacgct ataaagaaag
    24721 tatctttagc aaggaaagtt attgttatag tgataatatc tttagcttta atcatggtaa
    24781 ttagcactcg aagtataggt atgggattac tgttttctat atgtattttt ttaggattta
    24841 caatatatat aactaaaaga ctttcatatc ttagttacgt aatagaaggt acagaaagaa
    24901 taaaaaaggg agaattagat tataagataa aaattactgg gaatgataat tttacgtctt
    24961 tagctgaaaa tataaataat attggagaag gtcttgatag agctatagaa gagcaagtaa
    25021 aaagtgaaag aatgaagtct gaccttataa caaatgtatc tcatgatttg aaaactccac
    25081 ttacttctat aataaattat gtagatttaa ttaaaaaaga agaatcaata caaccagagt
    25141 atataaatga ttatataaat gtacttgagt caaagtcaaa aagactaaaa ttattgatag
    25201 aagatttatt tgaagcgagt agagtaagta gtggcaatat agaattacaa attagcaaga
    25261 ttgatttagt gcaactatta agacaaagta taggtgaact tgaagaaaaa ttatctaaaa
    25321 ataatttata tttaaaatta aatgttccaa atgataaggt gtatatatgg gcagatggaa
    25381 gaagaatgta tagagtattt gaaaatcttt tatctaatat agcaaaatat tccttagaag
    25441 aaactagagt ctatattgat gtatatgact atggtgaaaa tgtaaaggta actatgaaaa
    25501 atatatcttc ttatgaatta aattttgacc caagtgagat tatggaaaga tttaaaagag
    25561 ctgatgaatc aaggaatact gaaggaagtg gattagggct tgctattgca agagatttag
    25621 tagatttaca aggtggaaaa ttttatatag aaatagatgg agatttattt aaagcaaatt
    25681 tagagtttca aaaatatgaa gaagaaataa caaatatgga atgagatagt atttaagtat
    25741 atatattttt tttactgtcg aaagctttta ttataatata ttagaatatt tacagtagag
    25801 aatgaagagt aaaaacagag taactttaag tcactctgtt ttttatttaa aatcaataat
    25861 ataacaactt aaattaaaat tgtacacata gttttaaaat aacttataca ataaaacatt
    25921 gtccaaatat cacaagataa ttccaaataa atatatagat atcactcctg taataataga
    25981 aataccaata gatttaaact tatatgcaac aagaagtaca atcataaaag atataatttt
    26041 agggttagct atagataaat atagactatc tccattaaaa aatacatctt tagcagttaa
    26101 ggaagtaagt attgctacag gtataaattt catgattttt ttcaaaaaat caggcatctc
    26161 tttttttgaa aaaattaaca taggaagcac tcttggtaga tatgtaacaa tgtacattcc
    26221 aattataata aaaaatatat aattattatt cataagattc ctccttttta cagtaagatt
    26281 cttctataaa gaaaccaatt aaagatgcta aaattgatgc aactattatt actaaattga
    26341 ttttgaataa tgcatataaa ataacagaaa taatgattga tgatataaat actacaatat
    26401 aaatcttatt ttttatttga gaaactatta aagctataaa catagaagtc aatatgaagc
    26461 cagaaataga actgtctata gatatacttt ctcctaaaaa tgctccaata aaattagcta
    26521 aaactgatga aattaagcag aagaaattaa gataaatagc atttctatca gaccaatttc
    26581 cagcagtaaa tttttcataa ttaactgcaa aagtttcatc tgttatagta tgacaaaatg
    26641 gcaatataaa ttttggactt ttatttttta tgtacatgtt cagattagaa ctcattagaa
    26701 aatgtcttaa gttaactata aatgtagtca aaacaataga tgttacactt gcaccagtag
    26761 aaatcattga agctgcaatg aattgagaac ttcctccaaa tactaaagtt accattagtg
    26821 ctatttgaaa aggtgaaaga ccagattttt gtaatagtat tcctcctact atacctatag
    26881 gtatataacc taagaatata ggaattgaag caataaagct ttcttttaat tgttgagttc
    26941 tttccacaat aaatcactcc ttttgtatta aatgtattaa agtattagta aaacagaaaa
    27001 atagattaat tgtataattg caattataat taaaaataaa tttggattaa tatataaatt
    27061 actatacaac aaatagataa tcttaaacgg ttattaaatt ttacctattt gttattatga
    27121 tgtaataata catattaatc tctataagtt aattactatc tggtgtaatt ttattttaac
    27181 aacaaaaaaa aatacacaca attaaaatat tgtgtgcaat acaattattt ttcctcttct
    27241 aatagtcttt ttaatacgct cagaccagct ttaagttctt ctgtgctttc tgtagcacat
    27301 acagctattc ttattgcaga aattggtttt tcttttccaa cagcaaaacg ttcagaagca
    27361 tagacctgta caccttcttt aagtgcttgt atctcaaatt tttctgccat tattccatca
    27421 ggtagaatca accatctaaa tatacattct tcatttccca aaagattata tccagataaa
    27481 tattgattaa taatcttgtt tcttcttctt gcagatttac ggcgtgcatt aattaattta
    27541 tcggcttcac ctgatgtaat catgcgataa gcaatttctg ttaaaaaata agattgagat
    27601 agattaatgt tgtataatgc gcttgataat gcctctcgat actgtttagg tgtagagata
    27661 tatgctagcc gtaaactagg tgcaataatt tttgataaac tcgtaatata aattgtttga
    27721 ttgggcagat aggaagccac tggatttaaa tgtgtttcat taagtaaact atgaatagca
    27781 tcctcaataa caattaaatt gtatttagat gcaatatttg caatcatttt tcgtccattt
    27841 tgtgacatta tatgtgtagt tggattttga taatctggta ttatgtatag acctttaata
    27901 ttttcatttt tacaagcata taatagtcct tcttcactaa tctcattatc ttcttgttta
    27961 attggaatta gttgaatccc aagcatttta gctgctgtct ttattccagg ataagttaat
    28021 gggtctacac ctattctatc tccatgttga aacaaaccag ctaaaatagc aacaattgca
    28081 ttttgtccac cacttgcagg aagtaagcta tctgatgtag tttcaagccc agctttataa
    28141 attaatttgg caatagcttc tttttgccat ttagcaccat ctctttgtcc atattggaat
    28201 atagttttaa aatctatttc cttaattatg tgtttaaaca aagtattcat ttcttctagc
    28261 gtgaaatctg gattcattgt gcccatttca ataaatgtaa ttttattatt actggacatc
    28321 aagaatagat ttgaacgtgt atcataagat acaaaagttc cacttcctgt aactccactt
    28381 attagacctt ttttttcaca aattttaaaa gctctagaga tagtactcac attaacatct
    28441 aagaaatctg ccaattcacg ttggggtggt aatttagtac ctggtaataa aaatccattg
    28501 ttgatatctt gttctagttg ttctgcaaga gccttatata atatttgccc ttttgaaggt
    28561 ctctttggtt tccagttcat aggataattt tcaaaagaat taattggcat aagttttcac
    28621 ctcacattat taatttgatt ttttctttat ctaaaacaat aaattctaaa gatacaaata
    28681 aaaactgata ggaaataatt ctatcagttt ttgtctttta attgatttca aatcttccta
    28741 taatttttat accttcttta tcataaagag ggattgtttt tttaaatata ttaaaatttc
    28801 tttttcttgt atataaaaca gctttttctg gtgtctttgg ttggttatca caatcgtaca
    28861 aatttctttt ttttaactaa aagcaataat acataaaatt attattgcta atgatactct
    28921 taatgtggta tatagtcata gtgtcacatg tctatcaata gttttttcag taattattgt
    28981 aacgaatagt aggactcata aaatacttag aaatatgttt ttagatagat tttaaatata
    29041 taatctaact tatatctata aattaacact attattctcc aattccattt ctagtttttt
    29101 tataaattta ttaaattctt ctggttgcct ttttccaaac aatactctta caagagctga
    29161 attgattttt ccaaatatat tcctcttgct ttcactttca ataaaaataa gttttgtatt
    29221 ttctaagtca atatgtacta attcatatct agtaatagta ctttctcttt tattgcttgt
    29281 ttttatctca tatactctat ttttttcgaa attagttatt tcaaccttaa atcttttatt
    29341 atttttttgt tgtacaaatg ttcctactgc ttttttctca ttaaaattag gaaaatttag
    29401 tcttgcagat tttgtaaata tattaaatat gtcttttgca gaatatttta ataaaacttc
    29461 agttttaaat gtattcatat cgttttccct tctgtatata aatttaatat ttataactta
    29521 atttttaagt taaaatagta taatatgcca tattaaatca tgttaaaact atttatatag
    29581 ctaaaatctt acatatataa gtatgtatac tattatataa aaataaaatc ttaaaataga
    29641 aagggttaaa aacacagttt attataattt ttattgttga gtagatacgt actattatat
    29701 atgattgagc aagtttttca atcataaatt tataaagtat tttgcattaa aatttaaaca
    29761 aagagttaaa ttatttaaga ttatgaataa ctaatacatt tagtaaatta ctaaatatac
    29821 aaaatgtaaa tacttatcaa aatgtataaa tacttatgac atctagttac ttacagggtt
    29881 taagtagaaa aaaatatcaa agtaagtatg gcatgatagt tgcttatata tttattaaga
    29941 aaggagttat taagcatgga gttgagagat aaacttgtaa acatcataaa tacagaaaat
    30001 aaaaaagatc cattaacaga tgttcaaata gcaaagtttt taagtacaac tagagagaac
    30061 ataactaatt tgagaaaaga acttaatata agtaattcaa ggcaaagaag atatccttat
    30121 ttaaaatcag caatttcggc aatattacaa aagaataaga atatttctat atcagaaatt
    30181 acaagggaat tgatgacaga aggctttaat atatcgagaa gagttgtgga ggaactttta
    30241 cctaaagaaa gtttagaaat ggatgtagta gaggaatctg aagaagaatc gaatgaccca
    30301 tttgaaactc tgataggtaa taaagggagt cttagaaatg ctgtggagca ggctaaatct
    30361 gctatattgt atccaccaaa aggattacca acgttgatta ttggggaaag tggagttggt
    30421 aagagtttat tttctagaca tatgtatgag tttgcaaagc aaaaaaagat agtaaaagaa
    30481 agctccaatt ttgttgtatt taactgtgct gattatagtg acaatccaca attattatta
    30541 tctttgttat ttggatataa aaaaggtgca tttacaggtg ctgaatatga tacaccaggt
    30601 cttgtagaag aagctgatga aggagtttta tttttggatg aaatacatag attgcctcca
    30661 aaaggtcaag aaatactatt ttctatctta gataggggaa agtttaggag attaggtgaa
    30721 actaatgctg aaagaaaagt aagtattatg ttgattgggg caactactga aaatgtagag
    30781 actaatttat tattaacatt cagaagaagg ataccaatgc taataacttt gccaccatta
    30841 catgatagat tactaaaaga gaaaatagac cttatataca atatctttca acaagagtgt
    30901 aatagaataa atgcaaaaat atttgtagat aaaaatgtga ttgaaatact tgcactaaaa
    30961 aagtttagtg gaaatatagg acaattacaa aatatgattc aggttctttg tgcaagagct
    31021 tttatgaagt ttataaattc caaagatgaa gatagtgaat cgatagtagt agtagatata
    31081 aatgaagttt taaagcttaa agattctttt aaagatgctg cctttcaaga gattgaatat
    31141 acagagataa gaaaatattt gaaaaatgct atatttatac catttaattt agaagaatca
    31201 tcagtaaaag gaagtctttt aagtgatgaa tatatattac cagaggacat atacaaaaca
    31261 attgaaaaga aatattatga cctaaaatcc ttagacattg aagatataga tatagagaat
    31321 attttatgga cttttatttt aaatagattt gctgacttaa agtttaatct cgatagtaat
    31381 gaagaaattt tttcaatgag tgatttaaat agttttgtaa gtgatagttt agttaaactg
    31441 gtaaaagaac ttatgaatga tatagttgaa aaaaatatga atttagaagt aaataaaaat
    31501 atgttcaaat atctagcaat acacttagaa gaagctataa aaagaattaa gctaaatcaa
    31561 aagataataa atgtaaattt agaaaaaata aagattgact tttcaaaaga atatgaaatt
    31621 agtaaaagtt ttgcaataaa aattgaggaa tcaattggca ttaagattcc agatgatgaa
    31681 attggattta taacgctcta cataaagtct gctctaaaaa atgaagtgaa aaaagataaa
    31741 gtagggttaa taataatttc tcatggacgt atagctacag agactgtaaa tgtagttaaa
    31801 gaacttttag gtgtaaagtt tcctgtggct atagatatgc ctttagatga aaaaccaata
    31861 aatatataca ataaggcagt agaattgtca aaaataatag accaagggaa aggcatattg
    31921 tttttggtgg atattggttc acttacaaac ataggtcaaa tagtaaataa gagaaccaat
    31981 ataagcacta aaactattga tagagtagac ctcctaatgg cactagaagc aactagaaaa
    32041 gtttctatgg gagaggaaga acttgatgaa atattttttt ctttgctaaa agataggatg
    32101 ggatataact atgaattaga aaaacacata gataaatcaa atgcaattat aacattatgt
    32161 cttactggag aaggaactgc taagtatata agtaaaacgt tggaagaaaa gtatgataac
    32221 actaaatatt atcaaatgag tgcattggat gaaaatttat tttgtaaaat tgaaaatcta
    32281 aaagagacaa acaatatatt agctattgtt gggacaataa accctaagat accaggtata
    32341 aattttatac cctataataa agaacttttc aaaaatttgg atatctatct atcaaaatca
    32401 aaacaacaag atgacagacc agttaaatcg tatgaaagaa tgcttgatga ggatttagtg
    32461 atttttgaac cagatatata ttttaaaaag gatttattag aatatgtatg ttcaattctt
    32521 ataaataaag aatatgtaga aaaagattac ttagattctg ttttacatag agaagaaatg
    32581 cttccaacat attctaaagg agctataggt gtgcctcatg gagattcttc tactgtaaat
    32641 agtacaaggt ttgtttttgt taaactaaag aatcctattg attggggtgt aggtaatgta
    32701 aatttcatat ttatgccagt ttttcaggct aatgataaag agattgttaa aaatgttctt
    32761 gagatactaa aagatgcaga atttatgaac aatgccaata agtgttttga taaagatgct
    32821 tttagaagga ttatatttga taaatttaaa catctgtagc catagcaaaa aaattgagag
    32881 gagttagagt aatgaatgta gatttaatat cattgggttt agaatctaat gattatgaaa
    32941 gtgttattga agaattagga agtataatgt gtaaaaaaga atatgtaaaa gaaacataca
    33001 taaatgctgt cttggaaaga gaaaggacat taccaacagg tctagatatt ggagaaatgt
    33061 gtgttgctat tccacataca gattcaaagc atgtaaatga gtctaatgta gctgtaggga
    33121 tattgaaaaa tcctgtaaag tttaattcaa tgatagaccc aaaagataga cttgatgtag
    33181 aacttgtatt tttattagca gtaaagaacc cagattcaca agtaaaactg ttaaaagatt
    33241 taatgtcagt ttttcaaaat ataaagttat taaaaaatat aaaaaacgca tcaacaaaag
    33301 aagaagtagc taaattattg gattttatag aaatttaatg taggagaatt ttataaataa
    33361 aaaattaaaa tttaaacaat caaagtaagt attatttttt taataggttt aatcttatat
    33421 aaaataaaaa tttagagtga aaaattagga ggaaattatt atgaaacaat ttaatgtatt
    33481 atcagtttgt ggttcaggga cagttacatc atctatggta gcaggtaaat taaaagaagt
    33541 actaggtaat aaggggattt ctattactac aacagaagct agaccaacag aagcactaaa
    33601 tttagcacaa tcaggaagat ttgactttat aacatttacg agtccgcttc aaacaggcga
    33661 ttatggaata ccaactataa atgcatttgc ttgcctaact ggtatagggg aagaggcatt
    33721 ctttgaagaa gttttgactg ttattgaagg catagataag taagttttgg agacgtgaat
    33781 ttatagtatt taaatcaatg atttagatac tataataagc taatattaac taaatatttg
    33841 tggaaaaaac attttatatg ttgtcataaa ttaaaaaatt ataaaaatag tcacttaagt
    33901 attaaattaa gcttataaat atttataagt aggagggaaa aagatgttag aatttatgaa
    33961 atctataatc gatacatttg gttctgcaat tatagttcca attataatat tcataatagc
    34021 aaagatattt aaagtaacta ctaagaaatc gtttctttct gctgtgtatg caggagttgc
    34081 tttacaaggt tttacactga ttttaaattc atttacacca ataataacac cagttatcaa
    34141 taggatggtt gagagtacag gagtaaacct accagttttt gatgttggtt ggcaagcaac
    34201 atcattggtt gcattttcaa caagtgcagg tatgatatat ttaggtcttg gtatattatt
    34261 acaaacaatt ttatttttga taaaatggac agacgtgttt caaccatcag atttatggaa
    34321 taactattct tatatggtat ggggagcaat ggttatagga gtaacaggaa attttccttt
    34381 aggtatagca tgtatggttt tattaaactt atatagttta ttaatatcag agttagttgc
    34441 aaagagatgg tctagttact atagatatcc taattgtaca ataatagcta tgcataatgt
    34501 tgaggcttct gtgtttgcag tatttgcaga ccctatatac aataaattgg gattaaataa
    34561 aataaaatta aatccaaaag aattagagaa gaaattaggg tttttaggtg aaccaattac
    34621 tttaggtctt tttttaggta tgtttatagg tatattaggt aatatgacga gaataaatac
    34681 tatggaagct tggggagaaa taatgaaagt aggtatatct acaagtgcag tgatggcaat
    34741 tttccctaaa gtagcaagta tgtttgctca agcatttgca cctataacag aagcagctag
    34801 aaagattatg caaaaagctg gaaaccgtga gtggtacata gcagtaaatg atgctgttgg
    34861 atatggtgaa cctgcaactt taatatcagg tcttatatta attccaataa tgcttgtaat
    34921 agctatggta cttcctggta ataaggtatt accagttgtg gatttattgg caattccata
    34981 tatggttcaa ggtttagttg ccatacataa tggtaatata ccaaaagtat tagtttcagg
    35041 tataatttgg tttggattag gattatatgt ttgtacatct acagcaccat tatttacaga
    35101 tatggctaca aatataggtg tagctatacc tgcaggagca atgttaataa caagctttaa
    35161 tatactagga aaacctttga tgggattagt tttctttgca tttctaagtg caaatccaat
    35221 ttatataggt ctttcagttg taatttactt tgttctatgg gcattgttta gaaagaacaa
    35281 aacaagtatt cttgattatt tagaaaaaca agcacttaaa aatgtagaag aagagcctgt
    35341 agcagtttaa gtttataaaa atgaaataag aataattaaa ggagtttata attgatttta
    35401 tataagtatc agataatacc tgagaaatat ttaaatgaaa tatagacttc tttttatttg
    35461 ataatatttg taattataat gcattgtatt tttatagttg agttttctgt ataacctgct
    35521 atttaaaaca tactctttta tatttataca gtaatgtggt ttaattttat aaaatgtaat
    35581 ctctactggt aaaagacttt gtatataagg catttgcctg aataaaccat ttatcttttg
    35641 tatggcatag atattgctat atagaagtat atagcatgaa aggagatatt tatatgggag
    35701 ataaaatgag agcatcagta ttgtataatg taggtgatgt cagatatgaa atggtagata
    35761 taccagaaat aacagatacg caagtgcttg taaatgtaaa atatgttggg atatgtggtt
    35821 cagatttacc taggtctatg gtaagtggtt tgagtggaaa tacaaaatat ccattgattt
    35881 tagggcatga attttctggt gaagttgtta aaattggaga aaaagtaaat catattaatg
    35941 taggagatag agtagctgtt gcaccattag taccttgtag aaaatgtgat tattgtaatg
    36001 aaggtaattt tggcttgtgt gatgattaca atataattgg aacaagagta aatggagcgt
    36061 ttgcagaata tgtaagagtt ccagaagaac atattttaaa actaccagat acattggatt
    36121 atgaaactgc tgccggaatt gaaccagcaa ctatagctta tcatgggatt tcaaagtcta
    36181 atattagagt aggagatagt gtagttgtgt taggatgtgg tccaataggt cagtttgtta
    36241 tacaatgggc aaaggtgttt ggtgcatcta agattatagc agttgatatt tttgatgaaa
    36301 aattagaact ttctaaactt ctaggagcaa actatatact taactcaaaa gaagtaaatg
    36361 taatcaaaga aataaaaaaa ataacaaatg gtggtgctga tgttgtaata gagactgctg
    36421 gtagccgatt tacacaagaa caatctctat ttgtagcaaa aaagagagga aatatagtgt
    36481 ttgtaggtat atcacacaca gaattaccac ttagtgcaga cgctactgag tgtatattac
    36541 gtggagaact taccttgaaa ggttcttgga attcatatac aagcccttat cctggaagag
    36601 catggactgc aacattggat tttatgggaa aaggtgacat tatttttaaa cccatgattt
    36661 cacataaaat aggtcttaat gaagttggtg actttttaag taaaatgagc aagagagaaa
    36721 ttaatttcaa taaaatccta gtagaaatat aaaaatttaa taaaaaattc taaaagcaat
    36781 taaattttat aactatgaca ttaaataaaa taaaaataat tttcttaaat aaaatatagg
    36841 aggaagaaaa gtgttagaaa atttaaaaga agaagtatta aaagcaaact tagaattacc
    36901 taagaaaaag ctaattactt atacttgggg aaatgtaagt ggaatagata gagaaaaagg
    36961 attagtggtg ataaagccaa gtggtgtaga gtatagtaat atgactgtag aagatatggt
    37021 tgtagttgat ttagagggaa atatagttga tggcaaatta agaccttctt cagatacccc
    37081 gactcatcta gttttatata aagagtttga agaattgggg ggaatagtac atacacattc
    37141 aagttgggca acaatttggg ctcaaatagg aaaatctata ccatcttgtg gtactactca
    37201 tgcagattat ttttatggaa gtataccatg taccagaaaa atgactagag aagaaatttg
    37261 caatgaatac gaaaaggaaa ctggaaatgt aatcattgaa gaatttatgg gaagaaatcc
    37321 aattcattgt ccaggaataa ttgtaaatga ccacggacct tttacatggg gaaaagatgc
    37381 aaatgaggct gtacacaatg cagtagtttt agaagaagtc gcaaagatgg cttattatac
    37441 agagttaatg agtcctgata atattatgga taaggttctt atgaataagc atttttcaag
    37501 aaaacatgga aaaaatgcat actatggtca aaaatgatta tctggaggtg aattatgcta
    37561 gactctttaa aaggtaaaat tgtggaaata gcaattaaag cagagcatta tggtttatgt
    37621 aaagaaaaga ctggtaattt tagtattaga gataaggata ctggatatat acttataacc
    37681 ccatcaggta taggaagaga agaattaaaa gttgaacata tttgtgtatt ggatttggat
    37741 ggaaatgtaa tagaagttga gaaaggtatt aagccaagta gtgaggtatt gatgcatatt
    37801 gaaatataca aaacaagaga aaatataaat gccatatcac atactcattc tttatatgca
    37861 acagcatttt cagtagcaaa gaaaccaatt ataccaattg tatatgaatc agttaattat
    37921 ggcggttatg tagatattgc ttcatacgaa agaccaggaa ctttaaaatt agctaagagt
    37981 gtttcaaaat tactgataga tacagatgca tgcttattag aaagacatgg gttgacaact
    38041 gtaggtaatg atttagacga agcattatta aaatcaagat atgtggaaga ggtagcagaa
    38101 atatactata ggtctttagt attaaatcaa tttaaagaac ttgaagtagt agatgttgat
    38161 gagtttaaat cttggaaata cccagaagaa ataaagtttt aatctaaata attttcattg
    38221 aagtggttaa ttaaaatata tgtattattt atatcaatta ctatgtttta ttatgttaat
    38281 taccgtattt tgcaaatata tttattacat tttttcaaaa aaatatagaa tccgaaagcc
    38341 atataaaatt gacttgggat tctatacttt ttatttatgc atttttcttt atctgatttt
    38401 ctggagaatt tatatgttca aaatattttt tagtttcaga tactattata ggtgataatg
    38461 caagtaaagc tataaggtta ggtattgcca taagcccatt tacaatatca gcaattatcc
    38521 aaacaacttc taactttaag aaagcaccta ataacaccat agccacaaat acagttctat
    38581 acccattcat gccttttaca ccaaacagaa attcaaaaca tctttctcca taataactcc
    38641 atcccaaaat tgtagtaaat gcaaataatg ttaaactaac tgtaagtaat attggtccaa
    38701 atgtaggaat tgctccgtta aaagctgctt gtgtcataac agctccattt aggtctgaac
    38761 accacactcc tgaaataaca agagagaatc cagtaagagt acagattata atagtatcta
    38821 taaaagtacc tgtcatagat ataagacctt gttccgctgg ccattcagtt ttagcagcag
    38881 cagcagctat tggagcacta cctagaccag actcatttga aaatacacca cgagcgatac
    38941 catttctaat tgccagtgac atagttgctc ctaaaaaacc accagtagca gcagtaggtg
    39001 taaatgcact tttaattatt aacataaaag tttcagggat tttattccaa aaagatatta
    39061 aaatgattcc acagattaca acatatataa ctgccataaa aggtactatt ttagtagcta
    39121 cattagatat acttttaagt cctccaaata caactaaagc tacaaatact gctaatacaa
    39181 cccctgtaat tctagggtct atcccgaaac tattatttat tgcatctgtt attgaattta
    39241 cttgagtaaa agtaccgatt cctaaaagtg caactagtat accacttata gcgaaaaata
    39301 ttgcaagagg tctccatttt tctcccatac catttactat gtaatacatt ggcccaccag
    39361 acacttggcc atttttatct ttagttctgt attttattgc aagaacacct tctgaatact
    39421 tagtagccat tccaaagaat gctgctatcc acatccaaaa aagtgcacca ggtccaccag
    39481 ctttgatagc tgtagcaaca ccaacaatat taccagtacc aactgtagca gctagagcag
    39541 tacataaggc tgcaaaactt gaaacatcac cactaccttt gttttcagca gagaatatta
    39601 acttaagagc tcttggcagt ttagttattt gaacaactcc aagcttaaca gtaagtagta
    39661 taccagtacc aactaatagt accagtaggg gtggtcccca aataaaagca tcaactttgt
    39721 ttaaaatatc aattagattc ataaaaacac tccctcattt tttttgcttt acataatcaa
    39781 tagaattttt aatgaagtaa ttgacaggaa ataagtataa tttattaata atttctagtg
    39841 taataaaaaa agctaaatct aaaaaagatt cagctctgga tgtacactaa ttagcaacca
    39901 aaataaaagt attagtaaat actgtttttg gtagataatc cctgtccttt tgcctgagag
    39961 attgagcata aaagccttgc cccttcggcg cccataatgg gtctctccag agttccgtaa
    40021 attttacagt cctactttta aaagtacctg agagtgttac tccttcggtg tgctatatag
    40081 caactcttct ataaaatctt aaccggatat tgatttgtca tagcttattg tattaataat
    40141 attaatataa gtttttatgt tttgtcaact aaaaaattaa aaaacaaaga aaaaatataa
    40201 aaatgtaagc ctatttacga attataaact tagaaagatg agtaatatac gtgaaaatga
    40261 attttgtaat acacatacaa atgaagtgta aaataagttt taaataaaaa aataataaaa
    40321 tcttaaataa ttaattagat atgattaaat tatggtaata ttatagttac gatattaaga
    40381 aaagttctat ttagttagat tttaagcgta atatgagatt atgtatagag aaaggatgta
    40441 tttttagatg ggaaaaatat tagtgctagc agaaaaacct tctgttggaa gagatatagc
    40501 aaaagtttta gggtcaaaaa atgaaaaaaa tggttatata gaggggccaa agtatgtgat
    40561 aacttgggca ctaggtcatt tggttacact tgctgacccc gaaagttatg gagaaagata
    40621 taaatcatgg agcttagaag acctgccaat acttcccaag caccttaaga ctgttgtaat
    40681 aaaaaagagt ggaaagcagt ttaatacagt taaatcgcaa atgaatagaa atgatataga
    40741 tgaaatagtt atagcaacag atgcaggtcg tgaaggagaa cttgtagcaa ggtggataat
    40801 agaaaaatca caggtaaaaa aacctataaa acgtctttgg atttcttcaa gtacagacaa
    40861 agcaataaaa gacggatttg caaaattaaa aagtggaaaa gaatatgaaa atttgtatta
    40921 ctcagcaata gcacgagcag aagctgattg gattattgga ataaatgcaa ccagagcttt
    40981 gacaacaaag tacaatgcac agctttcttg tggaagagta caaactccta ctcttgcaat
    41041 gttgcttaaa agagaagaag aaataagaaa tttcaaacct aaagagtatt atggattaga
    41101 attaattgct acaaagggaa attcagatat aaaatttatt tggaatgata aaaacaataa
    41161 ttcttcaact tttagtaaag aaaagataga atccacatta aaaaaagtaa aaggtgtaga
    41221 cataaaaata tctgaagtaa acaagtcata taagaaaaaa tattcacctg cactctatga
    41281 tttaacagaa ttacaaagag atgcaaataa aatgtttgga ttttcagcaa aagaaacttt
    41341 atctataatg caaaaactgt atgaacatca taaagtactt acttatccta gaactgattc
    41401 tagatattta acatcagata ttgttggaac attaaaagat agaataaaag ctgtaaatat
    41461 tagtgattat tcaaagactt gtaataaatt attaaaaagc aatattatag ctaataaatc
    41521 gtttgttgac aattcaaagg taacagacca tcatgcaata ataccaacag aacagaaggt
    41581 attcatgagt gattttagtg acaaagagcg aaaaatatat aatcttgtag taaaaagatt
    41641 tttagcagta ctatctcctc cttttgaata tgagcagaca actataagtg caactgtaga
    41701 aggagaaata tttaaggcta agggaaacaa agtaataaat ttaggttgga aagaaagtta
    41761 taaagatatt gaagatgaag atgagtatga aagtatacca aatattttag aaaaagatgt
    41821 acttaaggtc aagggattaa agataacttc aggaaaaaca aatccaccac catacttaaa
    41881 tgagggaaca ttattgactg ctatggaaaa gaatggtcta gggacagttg ctacaagagc
    41941 agatataata gaaaaattat tcaattcatt tttaatggaa aagaaaaata aagatatata
    42001 tataacatca aaaggaagac aattattaga tttagttcca gtagacttaa agacaccaga
    42061 acttacagct tcatgggaaa agaaattatt ggatatttca aagggaaaac ttagtaaaaa
    42121 tacattcata aatgacatga aagattattc aaaagatatt gtactagaag taaaaaatag
    42181 tgataataaa tttaaacatg ataacttaac taaaaataga tgtccagaat gtggtaaatt
    42241 tatgttagag gtaaatggta aaaaaggtaa gatgttgatt tgtgaagata gagaatgtaa
    42301 tactagaaaa actatatcac aagtaaccaa ttcaagatgt cctaactgcc ataaaaaatt
    42361 agaacttcgt ggagaaggtg aggggagaat cttcacttgt agttgcggat acagagaaaa
    42421 gttgtcttct ttcaacaaga gaaagcaaga agaaaaacag aaggcatcaa aaaaagatgt
    42481 taatcaatat ttaaaaaatc aaaataaaaa tcaagagaca tttaataatc catttgcaga
    42541 agcattagct aagctaaaaa acaaataatt ttaaagttat tattatacac aattataact
    42601 ttaactgtat attagttata tgtactgata taatatagtg tatagtttag gcatgaaagt
    42661 agggctgtta aatggattta agtggcatat ttaaatacta ttgtaaagag tgtgaaaata
    42721 catggaataa ttcgagtgtt gaattatttg agaatataga aacgtatagt aaagattcac
    42781 aaaaaaagag ggaaaaagaa ttagataaat tgctaaatac aatatcagtt catttagaga
    42841 ggtatccaag tgatgctgta ttgagaaaaa tgtgggtaaa aaagggcgag gttttcttac
    42901 aaaagacatt ggaaaaagaa aatattttta agttagaaaa aatggatgta gaggatagaa
    42961 aaaaattttt agatataaca aaacagttta ttagagatgc tagaaaattt gatgatgatt
    43021 tacctatagg tgatattatg caagctatga ggaatgtatg gatttcaaat gcattacaat
    43081 tattatttgg taaagaagta tattattcaa aagctaactt tgcatatagt atgttatatc
    43141 catatactga taattattta gacaatacaa atatagataa aaatgataag attttattta
    43201 ataactggtt agaaaaaagg ctcctgggag aacacattaa atctaaggat tatcatgaaa
    43261 gtaaagtatc tcaaatgata gattatattg aaagtgtata ccctagagaa aagtttacag
    43321 aagtttatga atcgttatta ttaatattta aaagtcaagt aaatagttta aaacaacatg
    43381 gtaaggaaaa tcatttgtgt aaagaagatt tattatccat ttctattgaa aaaggaggtt
    43441 catccgtttt agtagatgga tatttaataa gtggattgat gacaaaggaa gaaatagagt
    43501 tttgtatagg atatggattt ttattacaaa tatctgatga tttacaagat ataaaagaag
    43561 atttaaaata caaccataaa actattatta cagagatgtc aaaagagggt actttagata
    43621 aagttgtaaa taaactaata aattttacta ttaagttaat agatagtttt aaaattaata
    43681 ataaaaataa atctgtaata actatgataa agaatgattg cttaatgtta attttatttt
    43741 ctgtagttta taatgctgaa tttttttctg taggatatat aaaagaagta gagaaattta
    43801 ttccatatac aatagattat tcattagaga ttgaagaaaa aataaaagaa aaatttaaaa
    43861 atatagatgt tttaaataat gaaaatgaat ataaagaaat gattgatatt atttgtgcag
    43921 agtagaaaaa aagggagtgt cttagaatag actttttagt ttatgaggca ctctttttgt
    43981 ataaaatcaa atgtattttc atcattttaa caattaaaaa gagcttatcc ctatttgaga
    44041 aagccctttt taatttaaat aaaaatgtca aggttaaact atttaaatgc agtaataatc
    44101 ccattatcat gtaagttttt tatgattgta gctgcgatag ggaatccaaa taatccagct
    44161 attccaaata gttgagcccc aacaaacata cacattaatg ttattaaagg atataggcca
    44221 atttggtgtc ctactacctt tggttctaat atttgtctaa caacggttat aattatgtat
    44281 agtattaaaa gtcctattgc taaattaata tttccattaa tgagtgagat aatcatccaa
    44341 ggtgtcaaaa tacttcctgt acccaagact ggcaaaatat caacaagtgc tatgatgaca
    44401 gatatagtaa atgcattttc aacctttagg atagtaagtc caataagtag ttctatgaat
    44461 gtcactgata gtagtattgc ataggctttt agtagtttta aaagagcatt aatactgcta
    44521 ttttttatat ttattatcat aaattgactt ttttctggaa attgttttaa gataaagttt
    44581 actatttttt gatagtcaaa agtaaagaaa aaagaagcaa ttaaagtaat aataagtttt
    44641 aacataaatg caggtgtttt acttgcaata ctagcaatag cattgagtgc atttgttgaa
    44701 atagaagcta ctaaagacat catagattga cttatattat cccaaccaag tattaatgct
    44761 aggttaacat taggtgtact agcatctatc tttgaaaata aagtatttag cgttggttgt
    44821 atacttgatt tatatatttc aggaagtcta aaaaatacat cacttacact tgcaaatatc
    44881 ttcacaccaa agctaactaa taaaaatata cacaacccat aaaaaattaa aagtattact
    44941 atagaaataa gtgtacgatt taaatttgta ttatttgtaa taagtcttat aataggtctt
    45001 aagatggatg caatgataaa actgattaca aaaggcatta ataatggcaa taagaatttt
    45061 aatacaatat atacaatact tgttattaaa actacatatg taaatttaat tataaaattc
    45121 ttttgctttt gaatatccat aatataaaac ctccaatgta tttgatatta ttctaaatat
    45181 ggtctttttt acagaaaata tactactgta tattgattat aaactataaa gcttatgtaa
    45241 agtaaataaa ttatgtaaaa tttaggttaa ttttgtataa agagatactt ttatatttta
    45301 caattaataa ccaaatacta aaaaatattt taaataaaga acttaaaatt gtgataaaat
    45361 taatttatag atattaaaaa aagtataata tatggttttt aagaggtgct aagatgaaaa
    45421 actttagaga tttaggtggg aacaaaactg aggatggcag aactgtaaag aagggtttat
    45481 tttataggtc tgcaaaatta tcaaatctaa gtgaaaatga tataaaaatt ttaagagagt
    45541 taaatattaa atatatattt gattatagaa gtgatgaaga agctcgtaaa catccatcaa
    45601 caataatatc aaatataaaa aatataagaa taccagcaat gagagagcta gaagaatcag
    45661 gaggaagttt tggttctatt gaagatatga ttgatggatt gtttgaaaaa gatggtgcat
    45721 ttaatatgtt aaataatagt tactataatt tgcctataaa taatccgtca tataaaaaat
    45781 tagtagaact tataagagac tattctaatt taccaatatt aaatcattgt acagctggta
    45841 aggatagaac tggtgtgggg agtgctataa ttcttatgat tttaggggta tcgagagaga
    45901 atataatgaa agattatcta aaaagtaatg attttgcaga taaagagata gaaagattta
    45961 tagaatataa gcctaaattt aaggacattc caaaagaaaa tttgaaatat atatttggtg
    46021 taaatgaaga gtatatgaaa actgcattta gaagaattga tgaagaatac attagtgtag
    46081 aagcatattt atatggagaa tttaatttaa ataaagaaga aataagaaaa ttaagaaatc
    46141 aatatctaga gtaaaaggtg agtttatgag tttaaatata acagcaagac agataaatat
    46201 aataaaaata ttgttaaatt caaaagatac aattagtggt attgccttaa gtcaagagat
    46261 aggatgttct tcaaaaacta tacaaaatga aataaaggat attaataaac aacttagaaa
    46321 tggtaaaatt ttgtcaataa gaggagttgg ttataaacta gaaggaag
//
LOCUS       DACTZW010000027        45807 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.027, whole genome shotgun sequence.
ACCESSION   DACTZW010000027 DACTZW010000000
VERSION     DACTZW010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 45807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45807
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.027"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(94..825)
                     /locus_tag="JAM15_07800"
     CDS             complement(94..825)
                     /locus_tag="JAM15_07800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798151.1"
                     /translation="MLSKKNVSLIILVIILSLLTAIFIFNNKNTNNKLKEVTKNNEEI
                     VPKNLEGLSIEQLIEIRDKAIDKNLEGLREFGEDSVKKRKDSILNFEFGLVAFVNKNY
                     SNLTEKEKLIRQINIVNYENSINDIMDPSGSFFELANQNYQVNEFLLKNGKDYKEWSY
                     EGLDFLIDHLEELCKFVDFDVKDVIDIIDPTIKTDLSEEQKKSLNDKLKKISSSDTLS
                     EEVKKEIKNWENNLNNLNMNKNNSN"
     gene            complement(1663..2406)
                     /locus_tag="JAM15_07805"
     CDS             complement(1663..2406)
                     /locus_tag="JAM15_07805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HAT6798152.1"
                     /translation="MNFLSDLHTHSIVSGHGYSTLLENINYCKENGIKILGTSEHGPK
                     MPGSPHRWYFHNIQNIPRIINNIIILRGCEANILDIKGDIDLEPFVIPRLDYLILSFH
                     EAVFSPNTLENNTKALINAINKHDNIEILGHLGNPNYPIDYELIIKLAIEKNILIEIN
                     NCSIKGVSRNGSSDNCKYIATLCKKYSAKIILTSDAHICFDIGNYEYSENILKEINFP
                     DELIMNYPKKLINHFHQKGKLLDVDYTNI"
     gene            2572..5139
                     /locus_tag="JAM15_07810"
     CDS             2572..5139
                     /locus_tag="JAM15_07810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAT6798153.1"
                     /translation="MTQKKLSRKEKVLICLKRLTEEHLNFNNGIRFGFDAEYIATEVG
                     INRSNASKELNQLIKESIIIKIKGKPVQYLYKESIESILGKKLNKGIFDNINSINEYS
                     ENDSIKDEYILESIKKENNIFNLVGCDGSLRSQIEQAKAAVIYPPKGLSTLIIGPTGV
                     GKSIFAEYMYKYSLTIKEDSDNAPFIIFNCADYSDNQQLLLAQLFGYVKGAFTGADKD
                     KYGIVHEANNGVLFLDEVHRLSAEGQEMLFLLMDKGIYRRLGEANKVHECRVMIIAAT
                     TEDPETAMLETFLRRIPVTIKIPSLEERGFQERMKLICYFFKEESVRIGVKLKVSKEV
                     IKAFILYKCKGNIGQLKSDIQLICARAFLDYMTYKRECVYVRLSLLPNNIRESLYGNN
                     RKEEFVQNFSFIGKDDIIFLPEEKDFESENLLIENKKYDLDFYGMIKETWNKLQQEGI
                     KESQIRSVIDGDIQKYSYNLMNTFIYNNSNQTAYNNIVNDSIATTVKYILQKHDKWSK
                     REGLDKLIKAIALHIQNLIERIKIGNIVKHPNKDEIMKERAYEYNIAKEILSNMSLMY
                     GVEFPEDEAIFLATFLYLSYVGLNEESIAILVIMHGESTASSMVNVANTLLDCNHAVA
                     INMGLEDRVQDILVQAVEIANKIDKGKGILILTDMGSILTFAKVIRDATGKEVKAIDM
                     VSTPIVIEATRKALTPEMTLEKLYFNIIESIKKHYGDMEVTYAEKDNGGRYFDRLLID
                     NISKTLTFLNGEKAYFILKEVINRISEHYSLVIQDELLVKFIFHCSCMIERVIIKESL
                     VYKSYEERISRNKELYLVIKESFKLVEETFDIIISDMEYANILDIFESQYDTDKFKS"
     gene            5369..5773
                     /locus_tag="JAM15_07815"
     CDS             5369..5773
                     /locus_tag="JAM15_07815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAT6798154.1"
                     /translation="MIGIIVMTHGSFSEEIIKSCELIAGPAERTAAIKLNRNDNIEDL
                     NKNFVEKLNELDEGDGVLVLADLLGGSPSNVASLNLKKGGKFHALTGVNLPMLLEALI
                     NREGKSLEELAEACIEAGQTGINNINKVLSSM"
     gene            5797..6294
                     /locus_tag="JAM15_07820"
     CDS             5797..6294
                     /locus_tag="JAM15_07820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAT6798155.1"
                     /translation="MSLVKYCRCDDRLIHGQVIYKWVKHLGVKKIVVVDDETTNDVIA
                     KGLIKMAAPKNIDLSILTVSESRRYFYNNQADDNVFVLIKNLDTANRMIEEGINIKKL
                     IVGRIPTGIGKKKISQNVYINKKEFLLIDEFIKKNINVSIQMVPDEEEVELNQNINRY
                     KGEFI"
     gene            6297..6698
                     /locus_tag="JAM15_07825"
     CDS             6297..6698
                     /locus_tag="JAM15_07825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIC"
                     /protein_id="HAT6798156.1"
                     /translation="MNKYKVIILCHGTWGKVLVEETNKNFGLSNQYEVLSLSSEKDVS
                     VFMKEVEEVVDKEDVKIIISDLYGGSTSSVAIAVAIRRGIDAINGLSLQTILIVDEEL
                     SKEDKLHTLPERIVKKNNNLCVDLIKEFKKI"
     gene            6716..7204
                     /locus_tag="JAM15_07830"
     CDS             6716..7204
                     /locus_tag="JAM15_07830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAT6798157.1"
                     /translation="MAKITLVRVDHRLIHGQVITKWVKIAQAQKIIIVDDFLGQDEFM
                     ADIYKMAAPSGVEVVILTAEDAGQAFQNNTLGDKNIFILFKNIDMANKAYKAGLKYEK
                     IQLGGIPNEAGKKMVFTAVSLGNEDVEQLNELNENGVEIVLQVIPEESSMTYENALKK
                     FK"
     gene            7231..7986
                     /locus_tag="JAM15_07835"
     CDS             7231..7986
                     /locus_tag="JAM15_07835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAT6798158.1"
                     /translation="MESVLMLAIVTGLWYWFAAGLAGYTLFSTLKSPLFIGFSLGLLW
                     GDVTTGMIVGASIEMVYLGMVAAGGNIPSDKCLAALIAIPVALQTGVNAEVAVSIAVP
                     LGVIGVLVNNLRRTGNAVLVHKADKYAEEGNTKGIWRCATLYSLIFGFVLRFPIVFVC
                     NFFGADLVQSLLDVIPQWLMNGLTVMGGILPALGFATTIFTIGKNKFLPMFIIGFFMV
                     QYFEISITAAAIFGVCIALLITFMKEDKRVGEV"
     gene            7986..8849
                     /locus_tag="JAM15_07840"
     CDS             7986..8849
                     /locus_tag="JAM15_07840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAT6798159.1"
                     /translation="MQEIKNKEVKNGQGPTEVNKTRVLTKKDVTKTYLRWWWTAELSN
                     SFERMQALAVCASFTPALEKLYKRKEDLVDALKRHLQFFNTQAIWGGLIHGTVLAMEE
                     EKATEGKIPGEVISGVKNGLMGPLAGIGDTLDFGTFQTIFLALGASFGAEGSVIGAFF
                     PIMFSILLFCEGYYLFHLGYSLGRDSIKKILSGGIVNKIIDGASILGMFMMGALSATT
                     VKLSTPLSFDIGGKAIVVQDTLNMIAPGLLPLGVVFFVYWGMKYKKWTITKLLVILVV
                     LALVGSFIGIF"
     gene            8896..9375
                     /locus_tag="JAM15_07845"
     CDS             8896..9375
                     /locus_tag="JAM15_07845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-2-amino-thiazoline-4-carboxylic acid
                     hydrolase"
                     /protein_id="HAT6798160.1"
                     /translation="MSEKMYTEKEYLEGIRGATGERAVWFYLLMKEAEKLGANPDDIC
                     KEAIYGFGKMRGQKYNVADTPGKMAEMLYNSKGQKVFEMELVENTDENGVLKFHHCPL
                     DAAWKEYGLTKEERKEICRLACYGDYGRVDCAQGVKLDFAQKCAHDDEVCELVFTKK"
     gene            9440..10747
                     /locus_tag="JAM15_07850"
     CDS             9440..10747
                     /locus_tag="JAM15_07850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HAT6798161.1"
                     /translation="MDISRSVDNSLNRTIEFLKELIKIDSQQGEPISQCPFGIGPKKS
                     LDKTLDYCANLGFSVKNIDNYIGYAEIGEGEELIGIPMHLDIVPPGEGWSVDPFSGAV
                     IDNIIYGRGVIDNKGAVSMLIHVLKNIEDMYPTINKRIRLIFGTNEETGMKCIKYYLD
                     KGEEIPSMGFTPDAMYPVVNGEKGRVHIRIEKEIKIDKSKPYIIVRGGTKENVVPSHC
                     TAKIINGIISELTTKGVAVHASNPEKGENAISKMVIKIVEDNMDFQHREDIELVSKYL
                     CSDYYGDALGINQYDEVFKNTTLNLGILKVNEEKIVCELDIRYGKNIVLNNIIDRFKK
                     VFCNGWKIEVIAHKDLHYVDESNLVLKKLLEAYEEVTDENGYTIAMGGGTYASWFKDM
                     VAFGPKFLAYKTGGHGVDERVPINHIRKNMEIYTLALIKLLEL"
     gene            11057..11197
                     /locus_tag="JAM15_07855"
     CDS             11057..11197
                     /locus_tag="JAM15_07855"
                     /inference="COORDINATES: protein motif:HMM:NF021468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2185 domain-containing protein"
                     /protein_id="HAT6798162.1"
                     /translation="MNGEGCILSNKITKECYKIGYMIREKSIDTYPDSGRGFMTWDEN
                     GE"
     gene            11709..12803
                     /locus_tag="JAM15_07860"
     CDS             11709..12803
                     /locus_tag="JAM15_07860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6798163.1"
                     /translation="MNELNIAKTLILKRKEKGITQDELANYIGVSKASVSKWETGQSY
                     PDITFLPQLATYFNITVDELICYEPQMMKEDINKLYNKLCKDFTVKPFDEVMDEIREI
                     IKKYYSCFPLIFRMGLLIVNHYDIVDEKKRELLISEALEIFIRIQETCNDIDICRQAK
                     SMEATCYILLNQPIQVIDLLQNSNFPMINESILLAQGQMMNGQMDEARETFQLGAYQN
                     LISLVQNLVGILQNADKLQMKEIERRILAISDIFELDTLSPAIMLSSYLTQTQINLIH
                     GDNEGAIKSLRKYVDLATRDIYPIIIHGDDFFNKLDRWISEIGTGITRDDTIVKAGIV
                     AAIKNNPMFSLLSENKEYKFLIEKLSLLEE"
     gene            12808..13008
                     /locus_tag="JAM15_07865"
     CDS             12808..13008
                     /locus_tag="JAM15_07865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLDc_N domain-containing protein"
                     /protein_id="HAT6798164.1"
                     /translation="MENLMEYLPLLIPVIILDLILIITALVHVLRHPNYKIGNKAIWI
                     IVVLFISLIGPILYFTIGRGEE"
     gene            13008..13925
                     /locus_tag="JAM15_07870"
     CDS             13008..13925
                     /locus_tag="JAM15_07870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016280896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6798165.1"
                     /translation="MNIVSINGLSKGFGNRKIIDNLNFTVPEGSVFGFVGKNGAGKTT
                     TMKMVLGLLEPDSGTIDVCGEKVTYGRTSSNRHVGYLPDVPEFYNYMRPLEYLSLCGE
                     ITGLSKKEIKIRSEELLSLVGLGNEKRRIGGFSRGMKQRLGIAQALLSRPKLLICDEP
                     TSALDPVGRKEILDIMLKIKDSTTVIFSTHILSDVERICDHVAILNKGSIALSGTLSE
                     IKSMHGKDRLLLEFASNNEIQKFKSSGGIKSLLKDSEETNMEIVLHGKDIKAIQKTVI
                     STLAEMNLCPVKMELIELSLENLFLEVVK"
     gene            13922..14680
                     /locus_tag="JAM15_07875"
     CDS             13922..14680
                     /locus_tag="JAM15_07875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6798166.1"
                     /translation="MREYIAFTKKEFKENIRNYKLLSLTILFLVFGIMSPLSAKFMPD
                     LIAHFAPTLKVTTAPTALDSWTQFSGNISGLGTSLTLIVFCNILSNEYSKGTLVIMLT
                     KGLSRSSVVLSKFSIAVIIMTIGFWLSFLCTYGYTMYFWPTANLNHIIFSAFNLWLIS
                     IMYISILILGCVLFRPAFASVLLVLAATAILSLISIPKQIAPYTPNFILSKNIDLVSG
                     KVTPPEFIIPIIVTIVISIVCLLLAVVLFNKKAV"
     gene            15063..16136
                     /locus_tag="JAM15_07880"
     CDS             15063..16136
                     /locus_tag="JAM15_07880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HAT6798167.1"
                     /translation="MEKSKVYFCDLYSNSQNKNVPNNVRRLFDEAGFKDLIEKNDQVA
                     IKLHFGEKGNTTYMSPVAVRQVVDKVKDCEGKPFLTDTNTLYTGSRTNSVDHLTTAIE
                     NGFAYAVVNAPVIIADGLYSRNYENVKIDKKHFESVKIGGEIYNSSAMIVMSHFKGHE
                     AAGFGGALKNLAMGCASAAGKQMQHSDVTPVVKEKKCVGCGKCVNSCPTKAISIVDKK
                     AVIDSDVCYGCGECPTVCPTRAVTIQWESDSDVFVEKMAEYAYGAVSNKKDKVGYITF
                     VMNVTPLCDCVPWSGRPIAHDIGILASTDPVAIEQACYDLICKEMGHDVFKHEHPHVN
                     GTRIIDYACEMGMGSKEYELIKL"
     gene            16206..16469
                     /locus_tag="JAM15_07885"
     CDS             16206..16469
                     /locus_tag="JAM15_07885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798168.1"
                     /translation="MKIYYEKENSKKANVNNIPSVFAFNFLRNFLTSKEYEETRKEYF
                     INNLTKSQVNQAMKDLKWLFREYEGLEVITMESLDGVKTRIVL"
     gene            16675..17652
                     /gene="bioB"
                     /locus_tag="JAM15_07890"
     CDS             16675..17652
                     /gene="bioB"
                     /locus_tag="JAM15_07890"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HAT6798169.1"
                     /translation="MEKYIIKLKNKVLREKEISYEEALNLISLDTNNKNDFDILLKSA
                     NEIREYFMGRKADLCTIMNAKSGKCSEDCKFCAQSSHYKTGVEEYSLLDYNEILNRAK
                     EMESKGVHRFSLVTSGKGMSGKEFNNILNIYEGLRENTNLKLCASLGIIDYEQAKMLK
                     SAGVTTYHHNVETCRDNFHNICTTHTYKDRIKTIKDAKKAGLDVCVGGIIGMNESEEQ
                     RLKMVFEIRELNVKSFPINILNPIKNTPMENYDVLEPMEILKTTAVFRFIIPNVYIRY
                     AGGRLSLKGYDKVGFNGGVNSAIVGDYLTTVGSGIENDKKMIIEQGFEL"
     gene            17880..18893
                     /locus_tag="JAM15_07895"
     CDS             17880..18893
                     /locus_tag="JAM15_07895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAT6798170.1"
                     /translation="MSITIKEIGELAGVSKTTVSKVINNKDENISQATREKILKIMKE
                     KNYVPNKLAQSLVTKKTNTIGLLIPDIRNPFFTDVSRGVEDKANEEGYNIILCNTDED
                     AKKEYEGIRTLSERMIDGIIFAASSNTNWKEANYKDIKIPTVLIDKKISMNKETLKGI
                     VKINNFEGAYIATKHLLDIGNKKIIYLSGPLQNEIAVDRLEGYKKALIECNLSYNPAY
                     VFEGKYKIEWGQEFIKNLEKIDFDAIFCANDLIAIGVIRGLKERGLSIPNDVSVVGFD
                     DIQTSSLISPSLTTVKQPSYDIGYKASEILINCLRGDKKESFDELIFKPELVIRDSTK
                     ESE"
     gene            18935..19825
                     /gene="rbsK"
                     /locus_tag="JAM15_07900"
     CDS             18935..19825
                     /gene="rbsK"
                     /locus_tag="JAM15_07900"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HAT6798171.1"
                     /translation="MGNIVVIGSVNMDMVCSVDKRPEKGETVLGNSFFTSPGGKGANQ
                     AISASKLGANVKMISCIGEDGLGEELIRNFRTNKVDYSLVSRNNHKSSGVAVITLCEN
                     DNSIVVVPGTNELVDIELIKKNEEEIKNADIVLLQLEIPLKTINYVVNFCFENRIKVL
                     LNPAPAVKLNEDIIEKVTYLTPNEHEYKIVFDTNEGIEEVLKKYPNKLVITEGKNGAR
                     FYDGEEIKHVSCISVDVQDTTGAGDTFNGALAVAITEGKNLYTAVEYAVVVSGLSVTK
                     LGAQSGMPYKEDVEKYLNNK"
     gene            19873..20835
                     /locus_tag="JAM15_07905"
     CDS             19873..20835
                     /locus_tag="JAM15_07905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAT6798172.1"
                     /translation="MRVRKILSLGIAGILAIGMLTGCSMEGPSKSDNKGGSDKKDLTI
                     GVSTITLQHQFFIDIDEGIKEKAKELGVKVIVNDPDQDVAKQTSAIEDFIQQNVEGMI
                     VLGTDNSAIVPAVEGAFEKMPVVTVDAVLNTENITSYVGTVSYDAGKKLGEYTKKYID
                     EKLGGKSEIAIVTDLKSQIQMQRIDGFKDALKGSANVKILNSQPGYDREESLNTVENL
                     IQSNPDVDIIYATAENSVLGAKAALESAKNKDVKIVGFDLTEEASSGITDGTILAMIQ
                     QQPKEMGRLAVEAVVKAIKGEKVEKNIPVPALLYDKENIKDFKN"
     gene            20889..22400
                     /locus_tag="JAM15_07910"
     CDS             20889..22400
                     /locus_tag="JAM15_07910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HAT6798173.1"
                     /translation="MSNIILKLSNIAKEFPGVRALDNVNFELFHGEVHALLGENGAGK
                     STMIKILTGAHSKTSGKFIFEGKEIENISPDISKKIGINAIYQELTVFDELTVAQNIF
                     MGKEINGKVLTNDKKMNEEAKKIFDNMGIDINPNSLVKELSIAQKQMVEIARVLSSET
                     KVLIMDEPTSSISKKETEILFRLINDLKESGVSIIYISHRMEELFEICDRITIMRDGK
                     TISTLNTKDVSSEEELVNLMIDRKLDQFFPKRKVEIKEEIMRVENLTKNNVFNDISFN
                     IRKGEILGIGGLVGSKRSEIVEAIFGLRTYDSGKIYLNNEEVKFKTPSDAIENGLGLI
                     TEDRKGTGLFLQMSVKENTTMAGLKKISKFKSIIDRKKEKEILEKYIEALKIKTPHMN
                     QVIQSLSGGNQQKAIIARWLLLQPDILIMDEPTRGIDVNAKAEIYNLMGDLVESGVSI
                     IMISSEIPELISMSDRIMVMREGHISGFLEGEEMVENNVLKLAFGGKINEFNN"
     gene            22384..23382
                     /locus_tag="JAM15_07915"
     CDS             22384..23382
                     /locus_tag="JAM15_07915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter permease"
                     /protein_id="HAT6798174.1"
                     /translation="MSSITKHKEEKSSPLLTKLTSVFRDQGSAAVGLVIIFIIMSVAS
                     SNFLTLDNLINVGRQISINAILAVGMTFVIITGGIDLSVGAVIALVGTFWATTVVNYN
                     APIWVGMILALAIGTILGVIKGAIISTQKLPPFIVTLAMLTIISGASFVFTGGRPISV
                     NTDAFKMLGRGYIGPIPIPVIIMIIVVIAGHFLLKRTNFGRHVHAVGGNEEAARLCGV
                     KVNKVIVKVYALAGLLTALAGIILSSRLASGSPTVGDGAELDAIAAVVLGGTNMMGGS
                     GSIVGTCIGVGIIGILGNGLNLLSVSSYNQMIIKGLVMLFAIWINNIKLKKSAKSK"
     gene            23566..24828
                     /locus_tag="JAM15_07920"
     CDS             23566..24828
                     /locus_tag="JAM15_07920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HAT6798175.1"
                     /translation="MKKILLDTLNSKKQEYIDYLKELVSIKTEDVGHGILGGFEKEGQ
                     EYIEKLANYIGFSVDRQEMSEELIKKAKNIYKEGNLGHNYQDRYNLICKYSDDLPGKT
                     IVFNGHVDTMPPGDISKWKYNPYRATEDNGKLYGLGTADMKSGLIASILAVKLIKDSG
                     LNVPGNVKIMSVVDEEGGGNGTINAVMNGIDGDCCIICEPSEQNLIVAHMGFVFFEVE
                     VKGVSLHCGSKWEGVNAIEKAMLLLQDIKELEHNWLMIYKHPLLPSPTINLGVINGGT
                     AGSTVPDKCVFNLCVHFLPNIMSYEQVVNDVTNVIMTRANGDLWLKDNKPNINIYQSG
                     LGFQMDKDSDFVVNAHKILEETLGKKLEIKGSTAGNDARLMKNLAEIPTLILGPGSIE
                     QCHSIDEYVEIKEYLDSILMYASLILNL"
     gene            24848..25591
                     /locus_tag="JAM15_07925"
     CDS             24848..25591
                     /locus_tag="JAM15_07925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HAT6798176.1"
                     /translation="MKKVLIVGESWVKNITHIKGFDTFVTTHYEEAVKWLKEAIESGG
                     YETVHMPAHVAADSFPYKLEELNEYDCIILSDIGSNTFLLSNSTFIDCNSNPDRLELI
                     KEYVNNGGALIMVGGYMSFTGIDAKARFGETAIKDVLPITMIDKDDRVEKPAGIIPEV
                     IDSEHPVLKGIPTEWPKFLGYNKTVARDNCPVLATIGGDPFVAVGEFGKGKSAIFSSD
                     CAPHWGPKEFTDWKYYNKLWVNMLDWLTC"
     gene            25764..27149
                     /locus_tag="JAM15_07930"
     CDS             25764..27149
                     /locus_tag="JAM15_07930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HAT6798177.1"
                     /translation="MDNLNKKFLMEYIDEIQGELRDISDKIWKNPELQYKEYYASNLQ
                     KECLKKHGFSIEGLEGMDTAFVASYGEGRPVIAVLGEYDALDGLSQKVSTTKEPIVDG
                     GAGHGCGHNLLGTGSIGAVIAVKELIKLKKLKGTIKYYGCPAEEDLSGKVLMIKKGFF
                     DGIDCAFSWHPFDINTPIRIPTLANYSVKFRYNGISAHAAQAPYNGRSALDAVELMNI
                     GCNYLREHIFDNCRVHYVTTNGGKMPNIVPDFAEVWYYIRGVKMEHVRDVFGRIVDIA
                     KGAALMTGTIMEYDIISGVYDYIPNTILTDILSQNMKLVGVQNYNEDDYYFADKLAET
                     VSIDKRSSVSSVLSGNKDITKMNLHDEVTDDTFTHNNCISLSLDIGDVSYIIPTAQCS
                     CSVWPIGISAHTWQSCASAGSDMGFKAMLLASKSISCSINDVMLDELVINKAKKELKD
                     TVGSFKYIPII"
     gene            27368..28207
                     /locus_tag="JAM15_07935"
     CDS             27368..28207
                     /locus_tag="JAM15_07935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798178.1"
                     /translation="MFGYVKINKMDLTFREYDYYKAYYCGLCKYLKRNHGEISRFSLN
                     YDITFLIVLLTAVYNPESISTEEVCIVNPFKKKKVITNDITEYAASMNILLTYYKLED
                     NLMDDKRIKDKLAYYIYKNKLKLAYEKYPEKAEYIKQQLNELNKLEKDKNINIDEVSS
                     IFGNIMGEVFVYKKDENERNLRMIGFNIGKYIYLLDAYEDLDEDFKKGRYNPFIEYID
                     KNDELKEKVKKIIVTSLGFLARGIDNLNLNKNVGIIENIIYSGVYLRYINILESRGGK
                     NVQ"
     gene            28197..28640
                     /locus_tag="JAM15_07940"
     CDS             28197..28640
                     /locus_tag="JAM15_07940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798179.1"
                     /translation="MYSNTYNNENFMRARAFIENSEFKKAYDFLKTLTDKCAEWYYLT
                     GFSAMNIGYYEEGEDFLKRAKFMEPENSEYSDALRSYTQYRNDYSNRADNYNRRRRND
                     LDGCCCCCCDDCCCCLGDDCCENCAKLWCLDSCCECFGGDLITCC"
     gene            28651..29142
                     /locus_tag="JAM15_07945"
     CDS             28651..29142
                     /locus_tag="JAM15_07945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798180.1"
                     /translation="MSIKVAYGGVLLALNVILLTLTNIIPVNTLFIMGLASLLVSIVI
                     MEWGFKSGIAFYIGSIVLGFIVMASKSQWIVYSLTFGIYGIVKYLIEKDRSIYIEYFM
                     KLVFANIMILILYFLLRTIVYIPINIFIIGSFEIAFIVYDYVYSSFIGYYNNRLRKML
                     FKK"
     gene            complement(29344..30072)
                     /locus_tag="JAM15_07950"
     CDS             complement(29344..30072)
                     /locus_tag="JAM15_07950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HAT6798181.1"
                     /translation="MKNIAAFFDIDGTLYRDSLMVEHFKKLIKYDIIDQKNWYKHARD
                     TFMDWDKRQGNYDDYLLEICDLYVDSLKGLDKTCINFTSDQVIKLKADRVYKYTRSRI
                     EWHLNQGHIVIFISGSPGFLVEKMAKKYNVTDFLGSDYVFENNIFTGTVIPMWDSISK
                     NNAINDFVVKYDLDLSNSYAYGDTNGDINMLKRVGNPIAINPTKELLSQISLDEEISK
                     NVEIIVERKDIIYSLSTDVNIVDI"
     gene            30197..31285
                     /locus_tag="JAM15_07955"
     CDS             30197..31285
                     /locus_tag="JAM15_07955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798182.1"
                     /translation="MNFNFAKATNSRLMGSLGLIINWIDDENNHFCQYFLLDAEGLGL
                     ADYVSLNNPTQEEAYMEEERLMGGFGSDRVELTKDESLFLVSYFGNKNLYYDKLLPGD
                     KCEYIDIIKNYKTDLIIEKLYNKICKRVDEEVEFINYMTMRFIAWDRESLKYFSGSDE
                     IANMHITNINGTLLKNVVSDKGQGRYISEALYEDNDGYYICKIAFCISKCYETGFRIN
                     SLLVTDKEPMYDFEVFDEISKSEFVSVYSVNSPEEFAGVFYRENPFLLKSNMNEGIFF
                     TRFNFNNDHVKENVYIINNDMKAIYYLMGNKFFIGTYNENDCNYINEISQSNYSDYIK
                     FEEKFFFEQNALYDFAESGSLDFDDFLE"
     gene            31569..34619
                     /locus_tag="JAM15_07960"
     CDS             31569..34619
                     /locus_tag="JAM15_07960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009273766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HAT6798183.1"
                     /translation="MKKILKRLCTGFLAFATIVTALPTTAVHAESKQYWTQSNERVGI
                     VEKVMNDGSIGSTFNEGHLTVDGEDAYCVDINTDFKNGYKTRADASTRMSADQIADVA
                     LSIEYAKQYTASHGGLSSNHAYLLRQLVVWQRLSVHLGWQCDNVRASYDEIPKATQDE
                     VFAGAKAFVKENKGRYECGGYIYSGEGQELGQFWANLNVGNATLQKSSTNTSITDGNG
                     NYSIAGATYGVFSDKDCKEQLATLTTDNNGNTETVEVKAGTVYIKELSAPTGYKVDNT
                     VYSLKIEAGKTATLKVADTPKVTDTLIELFKIDMETQKSNPQGDATLEGAEFTWKYYA
                     GYYNKDNLPAKPTRTWTTKTIAEKDSDGTIHYITRLADAYKVAGDSFYMQNGKVVLPL
                     GTLTVEEVKSPTGYLLDGAYMQANGSEEQIKGMYLTQITEDGDLAVLTGSNQFSVSDK
                     VIRGGVKIQKRDLETKDTKAQGGATFKDTGFTITTLNDNAVLVEGKLYKKNEVVKTIY
                     AGLDGIASTSTDLLPYGTYRIDEVEIGEGYLIDGAKPITFTITENGKIVDLTDEAHSI
                     YNQIKRGDLEGVKIGAGTHKRLADVPFRITSKTTGESHIVVTDDNGQFSTSADWASHK
                     HNTNEGKTSEDGVWFGTSEPDDSKGALLYDTYTIEELRCSSNKGFTLIPPFEIVISRN
                     KVTVDLGTLTDEYEKEISIHTTATSKDGEKSIIAGKEVTIIDTVKLDGLTKGTKYQLK
                     GWQMVKDENAELIIDGKRVENDYTFVADDEEMKVEIAYTFNASALGGKNLVTFEELYD
                     LSNPKEPVKVAEHKDIEDDGQTVLITERIIKIHTTATFEDGKKEIEVDKDVTIVDTVT
                     LEGLEVGTKYQLVGWQMLQEENAELIINCKRVENDYTFIADSENMEIQISFTFNASEL
                     GGQQLVTFEELYDVSNPDEPKKVAEHKDIVDEGQTVTIKEVPDVPEEPEKPETPTTPD
                     TPTRTDSPQTGDSTNLMAFIVMLIASAGSLAGTYFYKRRRMKKS"
     gene            34632..34818
                     /locus_tag="JAM15_07965"
                     /pseudo
     CDS             34632..34818
                     /locus_tag="JAM15_07965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843347.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            34848..35171
                     /locus_tag="JAM15_07970"
     CDS             34848..35171
                     /locus_tag="JAM15_07970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014080830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAT6798184.1"
                     /translation="MELKYVVPNMEKTFGNLEFAGESKVEQQRINGRYTPVSRSYNLY
                     SDVQRADDIIVTIPAKAGEKHFKPEQKIKLINPRITAEGYNIRGRGFTNYILLADDMF
                     PVESK"
     gene            35185..35571
                     /locus_tag="JAM15_07975"
     CDS             35185..35571
                     /locus_tag="JAM15_07975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005611082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAT6798185.1"
                     /translation="MRLANGIVLDKEKTFGVLKFSALRHEVRMENEDGSTSEEIKRRT
                     YDLKCSVQERMIQVSIPADVAVKDYPYNAEVELINPIADTVANANFRGADVDWYIKAD
                     DIILKNKGNQPAGNPQNNNPQGQPKK"
     gene            35651..36061
                     /locus_tag="JAM15_07980"
     CDS             35651..36061
                     /locus_tag="JAM15_07980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HAT6798186.1"
                     /translation="MKMPKENIDTAMFAPCGMNCLVCYKHCYHKKPCAGCLNSDKGKP
                     EHCRKCKIKDCIKDKGLSYCFECSDYPCKLIKNLEKSYNKRYQASLMENSDTVRQHGL
                     EIFMEKQKEKYTCSKCGGIISIHDRECSECQEKM"
     gene            36136..37530
                     /locus_tag="JAM15_07985"
     CDS             36136..37530
                     /locus_tag="JAM15_07985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAT6798187.1"
                     /translation="MRTILNKGHRIRASDKSLVYRFSLSMLLFLFIAVILLLNMKQLM
                     RTDWEHISLLENGLTLSPYNFITILIATGVCALVAFLYYRFCYDRFKQLLHRQKLARM
                     ILENKWYEADTVQDSGFFTDLQSRSREKIVWFPKIYYQMEKGLLHIRCEITLGKYQDQ
                     LLRLEDKLESGLYCELTDKTLHDGYIEYTLLYDMIANRISIDEVKAENGCLRLMKNLV
                     WEYDALPHALIAGGTGGGKTYFLLTIIEALLQTNAELYILDPKNADLADLGTVMPNVY
                     HTKEEMIDCVNAFYDGMVARSEEMKQHPKYKTGENYAYLGLPPCFLIFDEYVAFFEML
                     ATKESMSLLSQLKKIVMLGRQAGYFLIVACQRPDAKYFSDGIRDNFNFRVGLGRISEL
                     GYGMLFGSDVKKQFFQKRIKGRGYCDVGTSVISEFYTPLVPKGHDFLQTIGSLAYARQ
                     DGTATCEAKGDGTD"
     gene            37732..38931
                     /locus_tag="JAM15_07990"
     CDS             37732..38931
                     /locus_tag="JAM15_07990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAT6798188.1"
                     /translation="MNDTDFLNTLKAKRTDYGVSQTRLAIMAGISREHLSRIEAGKVA
                     LTEDMKHKLLEAVEKFNPEAPMFLLFDYVRIRFPTLDIQHVIKDILKLNVDYMLHEDF
                     GHYKYTEHYYIGDVFVYTSQDKEKGVLLELKGKGCRQFESYLLAQERSWYDFLMDALV
                     NGGVMKRIDLAINDRTGLLDIPELIEKCKNEECISKFRSFKNYGSGELVKHNEVNKDG
                     MGHTLYIGSFTSEVYFCVYEKNYEQSSKLGIPIEEVPIKNRFEIRLKNERAYYAVREL
                     LTHYDAELTAFSIINQYIRFADKEVGKRKSDWKTNVRWSWFIGEGRPPVKLTTKPEPY
                     TLQRTLNWLQRQVAPTLKMLKQIDAGNQTDYLKTIEQQAKLTDKHKQIVKQQTASVDE
                     LIKQEKE"
     gene            38941..39075
                     /locus_tag="JAM15_07995"
     CDS             38941..39075
                     /locus_tag="JAM15_07995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HAT6798189.1"
                     /translation="MWELIKDLLLVSLGMGIGVVLMCIMSVGKEADRHMIELKESEEK
                     "
     gene            39076..39297
                     /locus_tag="JAM15_08000"
     CDS             39076..39297
                     /locus_tag="JAM15_08000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798190.1"
                     /translation="MNFGQNLYNWFLSNAQSLVLMAIVVIGIYLGFKREFSKLIGFLV
                     VALVAVGLVFNAGGVKDVLLELFNKIIGA"
     gene            39567..40094
                     /locus_tag="JAM15_08005"
     CDS             39567..40094
                     /locus_tag="JAM15_08005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004030721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAT6798191.1"
                     /translation="MNKLILRPIISVEDKNIFISEIQEAFQNAYIKEFGEFEKTILPT
                     NDIEESFNERGAEAYVAEIDGERVGGAIIIIDNKTNCNSLDLLYVKANSQNTGNGFKI
                     WKAIEKLHPETRIWETHTPYFDKRNIHFYVNRCGFKIVEFFNPKHKDSHQTSETASNI
                     PEENNYFFRFEKEMS"
     gene            40389..40886
                     /locus_tag="JAM15_08010"
     CDS             40389..40886
                     /locus_tag="JAM15_08010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAT6798192.1"
                     /translation="MNEMRVCIESRLPTSEEACSAWFTFPVDEEEFEERIGVPIDSED
                     YRITEMELPFADEVGEDTTIEKLNDLYHIFESLPHDLQEDYGELTCYFTSLDELHQHR
                     HDVIHYSWCKNMADVARHLLDNDPAFSAIEERLTRYFDYEAYGQYLDDNGNFIETDHG
                     IYELP"
     gene            40902..41405
                     /locus_tag="JAM15_08015"
     CDS             40902..41405
                     /locus_tag="JAM15_08015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAT6798193.1"
                     /translation="MVEDMRVYIANLGKYNEGYLVGDWFSFPIDEEDVAERIGLNERY
                     EEYAVHDTENFPIEIGEYISIEELNEMFEMIEELPDYITDELDEFISHYGSLEEVYDH
                     KDDVYCYSDCETMTDVAYYFIDEMQMLGEIPSQLQNYIDYEAYGRDLSIEGTFIETSY
                     GMCEIPW"
     gene            41368..41508
                     /locus_tag="JAM15_08020"
     CDS             41368..41508
                     /locus_tag="JAM15_08020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006857179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798194.1"
                     /translation="MKQATVCVRYRGEKLEDQRQALLLLTAFSIGDSLKNGCPFLLCE
                     RS"
     gene            41518..41907
                     /locus_tag="JAM15_08025"
     CDS             41518..41907
                     /locus_tag="JAM15_08025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAT6798195.1"
                     /translation="MKKIKSYTGIWNVEKVLYAINDFNLPFPVTFTQITWFVITEFII
                     ILFGDLPPLSMIEGAFLKYFGIPVALTWFMSQKTFDGKKPYSFLKSQITFALRPKITY
                     AGKAVKLDKQVLHETITAVRSVSYVPD"
     gene            41894..44344
                     /locus_tag="JAM15_08030"
     CDS             41894..44344
                     /locus_tag="JAM15_08030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAT6798196.1"
                     /translation="MFPIKYIDNNLVWNKDNEVFAYYELIPYNYSFLSAEQKFIVHDS
                     FRQLIAQSREGKIHALQIATESSIRSIQEQSKKLVTGRLKDVAYQKIDEQTEALVSMI
                     GDNQVDYRFFLGFKLMVTEEQFNLKNMKKSAWLTFKEFIHEVNHTLMNDFVSMPNDEI
                     NRYLKMEKLLENKISRRFKVRRLETNDFGYLIEHLYGRDGIAYEDYEYLLPKKKLKKE
                     TLIKHYDLIRPTRCLVEESQRHLRLEHEDSESYVSYFTVNAIVGELDFPSSEIFYFQQ
                     QQFIFPVDTSMNVEIVENRKALSTVRNKKKELKDLDNHAYQSGSETSSNVVDALDSVD
                     ELETDLDQSKESMYKLSYVIRVSAPDLDELKRRCDEVKDFYDDLNVKLVRPAGDMLGL
                     HSEFLPASKRYINDYVQYVKSDFLAGLGFGATQQLGENIGIYIGYSVDTGRNVYLQPS
                     LASQGIKGTVTNALASAFVGSLGGGKSFCNNLLVYYSVLFGGQAVILDPKSERGNWKE
                     TLPEIAHEINIVNLTSDRENAGLLDPFVIMQNVKDAESLAIDILTFLTGISSRDGEKF
                     PVLRKAVRAVTQSDQRGLLHVIEELRKEDTPISCNIADHIDSFTDYDFAHLLFSDGTV
                     QNAISLDNQLNIIQVADLVLPDKDTAFEEYTTIELLSVSMLIVISTFALDFIHSDRSI
                     FKIVDLDEAWAFLNVAQGETLSNKLVRAGRAMNAGVYFVTQSSGDVSKESLKNNIGLK
                     FAFRSTDINEIKQTLEFFSIDKEDENNQKRLRDLENGQCLLQDLYGRVGVVQIHPVFE
                     ELLHAFDTRPPIQRNEVE"
     gene            44344..>45807
                     /locus_tag="JAM15_08035"
     CDS             44344..>45807
                     /locus_tag="JAM15_08035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAT6798197.1"
                     /translation="MKERIQGAFTRKKILHVLKMALFVVALFLILLSLLGTVVHATGL
                     VDDTINTENLYSKYPLSNYQLDFYVDNSWSWLPWNWLDGIGKSVQYGLYCITNFVWTI
                     SLYLSNATGYVVQEAYKLDFINDMADSIGKSIQTLAGVTQNGFSTSGFYVGFLLLIIL
                     VVGIYVAYTGLIKRETSKALHAVINFVVVFLLSASFIAYAPDYIKKVNEFSSDISTAS
                     LDLGTKIMLPDSDSKGKDSVDLIRDSLFSLQVQQPWLLLQFGNSDIEEIGSDRVEALV
                     SASPEDEDGETRENVVKTEIEDNDNNNLTIPQVVNRLGMVFFLLIFNLGITIFVFLLT
                     GMMLFSQILFIIFAMFLPISFLLSMIPSYESMAKQAIVRVFNTIMTRAGITLIVTVAF
                     SISSMFYNISTDYPFFMVAFLQIVCFAGIYMKLGDLMSMFSLNAGDSQSMGRRIFRRP
                     YLFMRHRARRMEHRLARAVSAGGVAGAVAGGVVASSKS"
BASE COUNT        16767 a         6047 c         9030 g        13963 t
ORIGIN      
        1 gtagcactat tttttagtgt cacagcccct tttttgttta taattatgta catttcacat
       61 tatcacgata taagcatttt tcttatgaga aaattaatta gaattatttt tattcatatt
      121 taaattattt aaattgtttt cccagttttt tatctccttt ttaacttctt cacttaaagt
      181 atcacttgaa gatattttct ttaatttatc attcaaagat ttcttttgtt cctctgaaag
      241 atctgttttt attgtaggat caataatatc tattacatct tttacatcga aatcaacaaa
      301 tttacacagt tcttctaaat gatcaattag aaaatctaga ccttcatatg accattcttt
      361 ataatctttt ccgtttttta acagaaactc attcacttgg taattctgat ttgctaattc
      421 aaagaatgaa cctgaaggat ccattatatc atttatagag ttttcatagt taacgatatt
      481 aatttgtctt attaatttct ctttttctgt taagttgcta taattcttgt taacaaaagc
      541 tactaatcca aattcaaagt ttaaaattga atctttacgt ttttttactg aatcttctcc
      601 aaattcccta agaccttcta aatttttatc aatggcttta tctctaatct ctattaattg
      661 ttctatactt aaaccttcta agtttttagg tactatttct tcattattct tagtaacttc
      721 tttcaattta ttattagtat ttttattatt gaaaataaat atagcagtta ataaacttaa
      781 aattattact aaaataatta aacttacatt ttttttactt aacatattaa acctcctttt
      841 ttaaataagt attgtacttg tgaaaaataa atttgtttat gaagataaca tttactactg
      901 tttgttctaa agattataat agaatatttt tttgatataa tctatatttt tcttattaaa
      961 ttttcttatt agatatttaa tatcaatgtt ttttagatag aaaagatttt aataactcta
     1021 aatatttaat aagtaaaata aaattattgc tttaaaatat atttttatat gttttaagtt
     1081 ttataataag taatattgta tgataaatta aatttaaata tttagagata agctattata
     1141 gaatttgctt agtttaagtt aaattttaaa atattcaaaa aggggctaga gtctggagat
     1201 ttttatttaa agaatacaca taaaaatttc tagactctca tcatttaaaa gaagtattct
     1261 aaatttatta tttataatta aatattatct gaaaaaatgg tatttttata cctttgtttg
     1321 ttatgcataa ttttacttag aacataagct ttatataaaa taattaaaaa tatacctaat
     1381 taaaataagt aaagaaagag ctatcataga acaaatttaa tttgctcatg cgacagctcc
     1441 tttttagatg atgctttttt agatttatac tataaggtat ataaaactaa gcttattaaa
     1501 aatgttataa tttctattgc tatcatagac catatcaatc catcaagttc ataaaagtaa
     1561 ttaagcttta ttaaatagct tctttattat aatttcttta tttcatataa tataaatagt
     1621 attaaaattt ttatgggagt taaagtaagc atgtattatt acttagatat ttgtataatc
     1681 aacatctagt aatttacctt tttggtgaaa atgattaata agttttttag gataattcat
     1741 tattaattca tctggaaaat taatttcctt taagatattc tcagaatact catagttacc
     1801 tatgtcaaaa caaatgtgag catctgaagt tagtatgatt ttagcactat attttttgca
     1861 aagtgtagca atatacttac agttatccga gctaccattt cttgacacgc ctttaataga
     1921 acaattattt atttctatta agatattctt ttctatagct aatttaatga ttaattcata
     1981 gtcgattggg tagtttgggt ttccaaggtg tcctaatatt tcaatattat catgcttatt
     2041 tattgcattt attaaagctt tagtattatt ctctaatgta tttggagaaa aaacagcttc
     2101 gtgaaatgat aagataagat aatctaaccg aggaattaca aaaggctcta ggtctatgtc
     2161 tcccttaata tctagtatat ttgcttcaca gcctcttaaa attataatgt tatttatgat
     2221 tcttgggata ttttgaatgt tgtgaaagta ccatctgtgg ggagaaccag gcatcttagg
     2281 accatgttca gatgtaccta gtatcttaat tccattttct ttacaataat taatattttc
     2341 tagtaaagtg ctatagccat gaccactgac tatagagtgg gtgtgtaaat ctgataaaaa
     2401 attcatataa attcctcctc tataaaagat gagggtaacg taatttatat tataaaacga
     2461 ataggaaaga aaatcaatag ttacataatt agacaaaaat attaaaatat tgtagaatta
     2521 agcttaataa taaatgttta acagtattac tgcttatagg ggaggttaac tatgacacaa
     2581 aagaagctat caaggaaaga aaaagtttta atttgcttga aaaggttaac agaagaacac
     2641 ttgaacttta ataatggcat tagatttgga tttgatgcag aatatatagc tactgaagta
     2701 ggtataaata gaagtaatgc tagtaaggaa ttaaatcaat taataaaaga aagtattatt
     2761 ataaagataa agggtaagcc tgttcagtac ttatataaag aaagtattga gagtattttg
     2821 ggaaagaaac taaataaagg gatatttgat aatattaact ctataaacga atatagtgaa
     2881 aatgattcta tcaaagatga gtatatttta gagagtataa aaaaagagaa caatattttt
     2941 aatttagtag gatgtgatgg aagtttaagg tcccaaatag aacaggctaa agcagcagta
     3001 atatatccac ctaaggggtt gagtacatta ataataggac ctacaggagt tggtaaatct
     3061 atatttgcag aatatatgta taagtatagt ttaactataa aagaagatag tgataatgca
     3121 ccatttatca tatttaactg tgctgattat tctgataatc agcaattatt attagcgcag
     3181 ctttttggat atgtaaaagg agcatttact ggagctgata aagataagta tggtattgta
     3241 catgaagcta ataatggagt attgttttta gatgaagttc atagattatc tgcagaggga
     3301 caagaaatgc tatttctgct tatggataaa gggatatata gaaggttagg agaggctaat
     3361 aaggtacacg agtgtagagt tatgataatt gcagccacta cagaagaccc agaaacagca
     3421 atgttggaaa cgtttttaag aagaatacct gtaactataa agattccgtc tttagaggaa
     3481 agaggctttc aagagagaat gaagcttata tgttattttt ttaaagaaga gagtgttagg
     3541 attggtgtta agttaaaggt ttcaaaagaa gttattaagg catttatttt atataagtgt
     3601 aagggaaaca taggacaatt aaaaagcgat atacaattaa tttgtgcaag agctttttta
     3661 gattatatga cctataaaag ggaatgtgta tatgtaaggc tctctcttct accaaataat
     3721 attagagaat cattatatgg aaataataga aaagaggagt ttgtacaaaa tttcagtttt
     3781 attggaaaag atgatattat ttttttacca gaagaaaagg attttgaaag tgaaaattta
     3841 ttaatagaaa ataaaaaata tgatttagat ttttatggaa tgataaaaga aacttggaat
     3901 aaacttcaac aagaaggtat taaagagtca caaattagaa gtgttataga tggagacata
     3961 cagaagtatt cctataattt aatgaatact tttatatata ataatagtaa tcaaacagct
     4021 tataacaaca ttgttaatga ttcaattgca actactgtaa aatatatttt acaaaagcat
     4081 gataaatgga gcaaaagaga aggattagat aaattaataa aagctatagc cttacatatt
     4141 cagaatttaa ttgaaagaat aaagattgga aatatagtaa agcatcctaa taaagatgaa
     4201 attatgaagg aaagagcata tgaatataac atagcaaaag aaatattatc taacatgtca
     4261 ttaatgtatg gagtagagtt tccagaagat gaagcaattt ttttagcaac atttctttat
     4321 ttatcgtatg tgggattaaa tgaggagagt atagcaatat tagtcataat gcatggtgaa
     4381 tctacagcat ctagcatggt gaatgtagcc aatactttac tggattgtaa ccatgcagtg
     4441 gcaattaata tgggattaga agatagagtt caggatattt tagtacaagc tgtagaaata
     4501 gccaataaaa ttgataaagg aaagggaatt ttaattttaa ctgatatggg gtctatttta
     4561 acatttgcta aagttattcg tgatgctaca ggaaaagaag taaaagcaat agatatggta
     4621 agtacaccta ttgtaataga agcaactaga aaggctctaa ctccagaaat gacattagag
     4681 aaattatatt ttaatattat agaatctata aagaaacatt atggagatat ggaagttaca
     4741 tatgctgaaa aagataatgg tggtagatat tttgatagat tactaattga taatattagc
     4801 aaaactttga cttttttaaa tggggaaaag gcttatttta tattaaaaga agtaattaat
     4861 agaattagtg aacactattc tttagtaatt caagatgaac ttttagtaaa gtttatattt
     4921 cattgttcat gtatgattga aagagtaata ataaaagagt ctttagttta taaatcatat
     4981 gaagaaagaa ttagtagaaa taaagaatta tatttagtta taaaagaaag ttttaagcta
     5041 gtagaagaga cattcgatat aattatttca gatatggaat atgcaaatat attagatata
     5101 tttgaatcac aatatgatac agataaattc aaaagttgat acaaaattta aaaatagcca
     5161 aaaggctatc ttttttttac tttttttgat acagatttga tacaggttga aaaaatcttt
     5221 tgatacatat cgaaataata agtttttaaa aaaaattgag taaaaagttt tgattaaatc
     5281 ctgtaaaata gccatttgtt attgatacac ataagttggc acggcaattg cttatataaa
     5341 aagtgaaaag aaaagtgagg tgaaattggt gataggaata atagttatga ctcatgggag
     5401 ttttagtgaa gaaattataa aaagctgtga acttattgca ggaccagcag aaagaacagc
     5461 agcaattaaa ctaaatagga atgataatat tgaagactta aataaaaatt ttgtagaaaa
     5521 gttaaatgaa ttagatgaag gtgacggagt tttagtatta gctgacctat taggaggttc
     5581 gccaagtaat gttgcaagtt taaaccttaa aaaaggtggc aagtttcatg cacttactgg
     5641 agtaaatctt ccaatgctac ttgaagcttt aattaataga gagggaaaaa gtttagaaga
     5701 gttagcagaa gcatgtattg aagcaggaca aactggtata aacaatatta ataaagttct
     5761 tagctcaatg taatagaaaa aggagtttga ttaaaaatgt ctttagtaaa atattgcaga
     5821 tgtgatgata gattaataca tggtcaagtg atatataaat gggttaagca tctaggtgta
     5881 aaaaagatag tagtagtaga tgatgaaaca accaatgatg ttattgctaa aggtttgata
     5941 aaaatggcag caccaaagaa tattgattta tcaatattaa ctgtaagtga atcaaggaga
     6001 tatttttata ataatcaagc tgatgataac gtttttgtat taattaaaaa tttagatact
     6061 gcaaatagaa tgatagaaga agggattaat atcaaaaaac ttattgttgg aagaatacct
     6121 acaggaatag gaaagaagaa aatatctcaa aatgtataca ttaataaaaa agagtttctt
     6181 ttaatagatg aatttattaa aaagaatatt aatgtatcaa ttcaaatggt acctgatgaa
     6241 gaagaagtag aattaaacca aaatattaat cgctataaag gagagtttat ttagcaatga
     6301 ataaatataa ggtaattata ctgtgccatg gaacttgggg aaaagtctta gtagaagaaa
     6361 caaataaaaa ctttggattg tcaaatcaat atgaagtttt atcactaagt tctgaaaaag
     6421 atgtttctgt atttatgaaa gaggttgaag aagtagtaga taaagaagat gtgaaaatta
     6481 taatatcaga tttatatgga ggatctacat caagtgttgc aatagctgtt gctataagaa
     6541 gaggaataga tgcaataaat ggacttagct tacagacaat tttaatcgta gatgaagaat
     6601 taagcaaaga agataaatta catacattac cagaaagaat cgtcaaaaaa aataataacc
     6661 tttgtgtgga tttaattaaa gaatttaaaa aaatataaat tatgaggtga atataatggc
     6721 aaaaataaca ttagtaagag tagaccacag attaattcat gggcaagtta taacaaaatg
     6781 ggtaaaaatc gctcaagctc aaaaaataat aatagttgat gacttcttag gtcaagatga
     6841 atttatggct gacatatata aaatggcagc accatcagga gtagaagtag ttattttaac
     6901 agcagaagat gcgggacaag cattccaaaa caacacttta ggagataaaa atatatttat
     6961 tctatttaaa aatattgata tggcaaataa ggcttataaa gctggactta aatatgaaaa
     7021 gattcaatta ggaggtattc caaatgaagc aggaaagaaa atggtgttta cagctgtttc
     7081 attaggaaat gaggatgtag aacaacttaa tgaacttaat gaaaatgggg ttgaaatagt
     7141 cctacaagtt ataccagagg aatcatctat gacatatgaa aatgcgttaa agaaatttaa
     7201 ataaaaaata taaattagga ggaattataa atggaatctg ttttgatgtt ggcaattgta
     7261 acaggattat ggtattggtt tgcagcaggt cttgcagggt ataccctttt ctcaacacta
     7321 aagtctcctt tatttatagg ttttagcctt ggattacttt ggggtgatgt aacaactggt
     7381 atgattgttg gtgcaagtat agaaatggtt tatctaggaa tggtcgcagc agggggaaat
     7441 attccatcag ataaatgtct agctgctctt attgcaatac cagtagcact tcaaactggt
     7501 gttaatgcag aagttgcagt atctattgcg gtacctttag gtgttatagg agtattagtt
     7561 aataacttaa gaagaactgg taacgctgta ttagttcata aggcagataa gtatgctgaa
     7621 gaaggtaata caaaaggcat ctggagatgt gcaacacttt attctttaat atttgggttt
     7681 gttttaagat ttccaatagt ttttgtatgt aacttttttg gagcagattt agttcaatca
     7741 ttattagatg ttataccaca atggttaatg aatggattaa cagtaatggg tggtatatta
     7801 cctgcattag gttttgcaac aacaatattt actataggta aaaataaatt cttaccaatg
     7861 tttattatag gattttttat ggttcaatat tttgaaatat caattactgc agctgcaata
     7921 tttggtgttt gtatagctct tttaattacc tttatgaaag aagacaaaag ggtaggtgaa
     7981 gtataatgca agaaataaaa aataaagaag ttaaaaatgg acaaggtcca actgaagtta
     8041 ataagacaag agtacttaca aagaaagatg taacaaaaac atatctaaga tggtggtgga
     8101 cagcagaatt atccaactct tttgaaagaa tgcaagcatt agcagtttgt gcaagtttca
     8161 ctccggcttt agaaaagtta tataagagaa aagaagattt agtagatgcg ttaaagagac
     8221 acttacaatt ttttaatact caagctatat ggggaggatt aattcatggt acagttttag
     8281 ctatggaaga agagaaagct actgaaggaa aaatcccagg agaagttatt tcaggtgtta
     8341 agaatggtct tatgggacct ttggctggaa ttggagatac tttagatttt ggtacatttc
     8401 aaacaatatt cttagcttta ggtgcttcat ttggagcaga aggaagtgtt ataggtgcat
     8461 ttttcccaat aatgtttagt atattactat tttgcgaagg ttattactta tttcatttag
     8521 gatattcttt aggtagagat tcaattaaga aaattctatc aggtggtatt gtcaataaga
     8581 taattgatgg tgcttcaatt ctaggaatgt ttatgatggg agcattatct gcaactacag
     8641 ttaagctttc aactccgcta tcatttgata ttggtggtaa agcaattgtt gttcaagata
     8701 cattaaatat gattgctcca ggtttattac cacttggtgt tgtattcttc gtatattggg
     8761 gaatgaaata caagaagtgg acaataacta agctattagt aattttagtt gtattagcat
     8821 tggtaggatc attcattgga atattctaat tcacagtgat taaaatatag aatttaattt
     8881 taggaggaga aagaaatgtc agaaaaaatg tatacagaaa aggaatattt agaaggaatt
     8941 agaggagcaa caggagaaag agcagtatgg ttctatcttc ttatgaaaga agctgaaaaa
     9001 ttaggagcta atccagatga tatatgtaaa gaagcaatat atggatttgg taaaatgaga
     9061 ggtcaaaaat ataacgtagc agatactcca ggaaaaatgg cagaaatgtt atataacagt
     9121 aaaggacaaa aagtgtttga aatggaatta gtagaaaata cagatgagaa tggcgtttta
     9181 aaattccatc actgtccatt agatgctgct tggaaagaat atggattaac taaagaagaa
     9241 agaaaagaaa tttgtagatt agcttgttat ggggattatg gaagagttga ctgtgcacaa
     9301 ggtgttaaat tagattttgc tcaaaaatgt gctcatgatg atgaagtttg tgaattagta
     9361 tttacaaaaa aataattttt aatgctaaaa gcctgttctt taaggacagg ctttaaaaag
     9421 atagaaagta ggttgattta tggatataag cagaagtgta gataatagtt taaatagaac
     9481 catagaattt ctaaaagaat tgataaaaat tgattcacaa caaggtgaac ctatttcaca
     9541 atgtcctttt ggtataggac ctaaaaaatc tttagataaa actttagatt actgtgctaa
     9601 tttaggtttt agtgttaaaa atattgataa ttatattgga tatgcagaaa ttggagaggg
     9661 agaggaatta atagggattc caatgcattt agatatagtt ccaccaggag aggggtggag
     9721 tgtagaccca ttttcgggag cagtaattga caatattatt tatggaagag gtgtcataga
     9781 taataagggt gctgtatcta tgcttataca tgtattgaaa aacatagagg atatgtatcc
     9841 tacaattaat aaaagaataa gattaatttt tggtacaaat gaggagacag gtatgaaatg
     9901 tatcaaatat tacttagata aaggtgaaga aattccaagt atgggattta ctccagatgc
     9961 tatgtatcca gtggttaatg gagaaaaagg aagggttcat ataaggatag aaaaagaaat
    10021 taaaattgac aaaagtaaac cttacataat agtaagggga ggaactaaag aaaatgttgt
    10081 tccatctcat tgtactgcaa aaattattaa tggaattatt tcagagttaa ctactaaagg
    10141 agtagctgta catgcaagta atcctgaaaa gggagaaaat gctatatcta aaatggtaat
    10201 aaagatagtt gaggataata tggattttca gcatagagaa gatatagaat tagtttcaaa
    10261 atacctttgt agtgattatt atggagatgc attggggatt aatcaatatg atgaggtatt
    10321 caaaaacact accttaaatt taggaatatt aaaagtaaat gaggaaaaaa tcgtatgtga
    10381 gttagatata aggtatggta aaaatatagt tttaaataac ataatagata gattcaaaaa
    10441 ggttttttgt aatggttgga aaatagaggt tattgctcat aaagacttac attatgtgga
    10501 tgagagtaat ttagtactta aaaaattatt agaagcctat gaagaagtaa cagatgaaaa
    10561 tggatataca attgctatgg gtggtggcac atatgcaagt tggtttaaag atatggtggc
    10621 gtttggacct aagttcttag cgtataaaac tggtggtcat ggagtagatg aaagagtacc
    10681 aataaatcat atacgaaaga atatggagat atatactttg gctttaataa aactattaga
    10741 attgtaaaag aagaagagac tttatgtgca aatttacaga tatcttaaaa agagagataa
    10801 aacgagttca accttattta aatgttcaac accatcaaat ggggctgtct caaaatagag
    10861 ataagcctct tacttattgt tgaaatgatg aaaatatatt ttacttcata caaaaaagag
    10921 tgccttatga agtaaaaagt taattttgag acaccctcat ttgatgatgt tgaagagaaa
    10981 ataagtatga aattattaaa aaagatgatt ttataaaagt taaggttgaa aagagaagtt
    11041 aattaaatgg aattagataa atggagaagg ctgtatacta tctaataaaa taacaaaaga
    11101 gtgttataaa attggttata tgattagaga aaagtctatt gatacttatc cagatagtgg
    11161 acggggattt atgacttggg atgaaaatgg agaataataa aaattatagt ttatacaatt
    11221 taataagata tatgtacaag cagttaatct aaatgattga ctgcttttct tttatagatt
    11281 tttatataat agacaattac taatacatga tagttgcctg ttataattag aggaatagat
    11341 acgaataata actttataaa agaattaaat ggaaaattga agagttatat tcaggatttt
    11401 aaaaagaata tgaaatgaga aatgaaaata aggtgtttat attaaaagag gttttacaca
    11461 aaatacttaa aaacgtgata aataaaaact gtatttagat aaattaacta ctagttttat
    11521 atataatatg gattttgttt acaaagttta catatttcac aaaatatttt taaaatatat
    11581 ttaaaaatat attttatata cttgttcgtt tgtttctctg tggttgattt tttcgtcaaa
    11641 agtcaacttc aaatcgcttg ttagctttac atgtttaagg atataattat acataaggag
    11701 ggattgacat gaatgaatta aacatcgcaa aaacgctgat tttaaagcgt aaagaaaaag
    11761 gaattacaca agatgaactt gcaaattata taggtgtttc taaagcttct gtatctaaat
    11821 gggaaactgg acaaagctat cctgacataa cctttttacc gcaactcgcg acatatttca
    11881 acattaccgt tgatgagtta atatgttatg aacctcaaat gatgaaggaa gatattaata
    11941 aactgtataa taaactgtgc aaagacttta cagttaaacc atttgatgaa gtcatggatg
    12001 aaataagaga aatcataaaa aaatattatt catgttttcc tttgattttt cggatgggtc
    12061 ttttaatagt taatcattat gatattgtag atgaaaaaaa gcgtgaacta ttaattagtg
    12121 aagcattaga aatatttatt cgtatacagg aaacttgtaa tgacatagat atttgccgtc
    12181 aagcaaaaag tatggaggca acttgttata tattgttaaa tcaacccata caagtgattg
    12241 atttattgca aaacagcaat tttcccatga taaatgaatc tatacttctt gcacaggggc
    12301 aaatgatgaa tggtcaaatg gatgaagcaa gagaaacatt tcaacttggt gcatatcaga
    12361 accttatatc attagtccaa aatctagtgg gtattttgca aaatgcagat aaattacaaa
    12421 tgaaggaaat agaaagacgt attctagcaa tttcagatat atttgagctt gatacattat
    12481 ctcctgctat tatgctttct tcatatttaa cacagacaca aattaattta atacatgggg
    12541 ataatgaagg agcgattaaa tcattacgaa aatatgtaga tttagcaaca cgtgatatat
    12601 acccaattat aatacatggg gatgactttt ttaataaact tgacagatgg atttctgaaa
    12661 ttggaacagg tattacacgt gatgatacaa tcgtaaaagc aggtattgtt gctgctatta
    12721 aaaataatcc aatgttttct ttattaagtg aaaacaaaga atacaaattt cttatagaaa
    12781 aattatcttt attggaggaa taagattatg gaaaatttga tggaatattt accacttttg
    12841 attcctgtta ttattttaga tttaatactt ataattactg cacttgttca tgtattgaga
    12901 catccaaatt ataaaattgg aaataaggca atatggatta ttgtagtact gtttattagt
    12961 ctaataggac caatcttgta ttttacaata ggaagaggtg aagaatgatg aatattgtct
    13021 caataaatgg attatcaaaa ggttttggta atcgaaagat aatagataat ctaaatttta
    13081 ctgtaccaga agggtcagtc tttgggtttg taggtaagaa tggtgcaggt aagactacaa
    13141 caatgaaaat ggtacttggg ttacttgaac cagatagtgg aactatagat gtttgtggtg
    13201 agaaagtgac atatggaaga acaagttcta atcgtcatgt aggttatctg cctgacgttc
    13261 cagagtttta caactatatg agaccacttg aatatctttc tctttgtggt gaaattacgg
    13321 ggctttcaaa aaaagaaata aagataagga gtgaagagtt gttatcactt gtggggcttg
    13381 gcaatgaaaa gagacgaata ggtgggtttt ctcgtggaat gaagcaacga cttggtatag
    13441 ctcaagcttt gctttcacgt cccaaattac ttatttgtga tgaaccaaca agtgcacttg
    13501 accctgttgg tcgaaaagaa atattagata ttatgcttaa aatcaaagac tcaacaactg
    13561 taatattttc aacacatata ctatcagatg ttgaaagaat ctgtgaccat gttgctatac
    13621 taaacaaagg aagcattgct cttagcggta cactttcaga aataaaaagt atgcacggaa
    13681 aggatagact tttactggag tttgcaagta ataatgaaat tcaaaagttt aagtctagtg
    13741 gtggcattaa atccttacta aaagattcag aagaaactaa tatggaaatt gttttgcatg
    13801 gtaaagatat aaaagcaata caaaaaacag ttatatctac actcgcagaa atgaatcttt
    13861 gtccagtaaa gatggaacta atagaattgt cacttgaaaa tttgtttttg gaggtagtaa
    13921 agtgagagaa tacatagcat ttacaaaaaa agagtttaag gagaacataa gaaattataa
    13981 attacttagt ttgactattt tatttttagt atttggaata atgagtcctc tttctgcaaa
    14041 atttatgcca gacttgattg ctcattttgc tccaacttta aaagttacta ctgcaccaac
    14101 tgctttagat tcttggacac agttttctgg aaatatttct ggtcttggaa cgagtttaac
    14161 tctaattgtt ttttgcaata ttttatcaaa cgaatattct aaaggaacac tcgttattat
    14221 gttgactaaa gggttatcac gttcatctgt agtattgtct aaattttcta ttgcagtaat
    14281 tattatgaca attggttttt ggttgagctt tttatgtact tatggatata caatgtattt
    14341 ttggccaact gcaaatctta atcatattat attttcagca tttaacttat ggttaattag
    14401 tattatgtat atttccatat taattcttgg gtgtgtacta tttagaccag catttgcaag
    14461 tgtgttactt gtattagcag caactgctat tttgagtttg atttctattc ctaaacagat
    14521 tgcaccttat acgcctaatt tcatattatc aaaaaatata gatttagttt caggtaaagt
    14581 gacacctcca gaatttatta ttccaatcat tgtaacaatt gttatttcga tagtatgtct
    14641 gttattagct gttgttttgt ttaataaaaa agcagtttaa ggatattttt attataaata
    14701 caaatagtgc tgtattgtgg gaaaatgtgt ttagtattgt agaagaatat atttaagtaa
    14761 aaaagaggct gtctcaagat agagaaataa gcctcttttt tattttagtc ctcctcacta
    14821 tactttataa taattaagtt attaccttaa ggaactatct aaaaaaagag atatagatta
    14881 taatctaatg cttatcagtt atttgaggtg tttagtatat agagtctaaa gtagtgaagg
    14941 actaaaataa tattgttttc attaaataaa gataagaatc tttaattgtg gtaaaatata
    15001 ctaaaaaatc attttaaaag tgataaaatt attttaagta aatattttaa aggggtgtag
    15061 atatggaaaa gtcaaaagta tatttttgtg atttatactc aaattcgcaa aataaaaacg
    15121 taccaaacaa tgtaagaaga ttatttgatg aagcaggatt caaagattta atagaaaaga
    15181 atgaccaagt cgcaattaaa cttcactttg gagaaaaggg aaatactaca tatatgagtc
    15241 ctgtggcagt tagacaagtg gttgataagg ttaaagactg cgaaggaaag ccatttttaa
    15301 cagatacaaa tacactgtat acagggagta gaacaaattc tgtagaccat cttacaactg
    15361 ctatagaaaa tggatttgct tatgcagttg taaatgcacc agtaataatt gcagatggat
    15421 tatatagtag aaattatgag aatgtaaaaa tagacaaaaa acattttgaa agtgtaaaaa
    15481 taggtggaga aatttataat tcttctgcaa tgatagtaat gagtcatttt aaaggtcatg
    15541 aagcagcagg ttttggagga gcattaaaaa acttagctat gggatgtgca agtgcagcag
    15601 gaaaacaaat gcaacattct gatgttactc cagtagtaaa ggaaaagaag tgtgtaggtt
    15661 gtggaaagtg tgttaattct tgtcctacaa aagctataag tatagtggat aaaaaagcag
    15721 ttatagattc tgatgtatgt tatggatgtg gagaatgtcc aactgtctgt ccaactagag
    15781 cagtaactat acaatgggaa agtgactcag atgtgtttgt cgaaaagatg gcagaatacg
    15841 cttatggagc agtatcaaat aaaaaagaca aggtagggta tataactttt gttatgaatg
    15901 taactccact ttgtgattgt gtaccttggt caggtagacc aattgcccat gatataggaa
    15961 tattagcatc aacagaccct gtagctattg aacaagcatg ctatgatttg atttgtaagg
    16021 aaatgggtca tgatgttttc aaacatgaac atcctcatgt aaatggaact agaataatag
    16081 actatgcatg tgaaatgggt atgggaagta aagaatatga attaataaaa ttataagaat
    16141 agtagcactt aaatgcatat aattattgta agagaaatct aaaagtatca aaggagtatg
    16201 catttatgaa aatttactat gagaaggaaa acagcaagaa ggctaatgta aacaatattc
    16261 caagtgtatt tgcgtttaat tttctaagaa actttttgac tagcaaagag tatgaggaaa
    16321 ctagaaaaga atattttata aataatctaa caaaaagtca ggttaatcaa gccatgaagg
    16381 atttaaaatg gctatttaga gaatatgaag gcttagaggt tattacaatg gaaagcttgg
    16441 atggagttaa gacaaggata gttttataaa ccagtaagaa ttatattcta ataaaaaata
    16501 ctgctttaat aataatatgt ataatctata tactaatatt attttgaagc agtatttttt
    16561 tgtgtatagt aaacttgtgt ctaaaataaa gttgaccaat aaatgttata tatgcaatac
    16621 tatatataat aagtaaacta cataaaaata ttaagttgac aaataggagg atatatggaa
    16681 aaatacataa taaaattaaa aaataaagta ttgagagaaa aagaaataag ttatgaagaa
    16741 gctcttaatt taataagcct tgatacaaat aataaaaacg attttgatat tctattaaaa
    16801 tctgcaaatg aaataagaga atattttatg ggaagaaaag cagatttatg tacgataatg
    16861 aatgctaaat ctggcaaatg tagtgaagac tgtaaatttt gtgctcaatc atctcattat
    16921 aaaactggtg tagaagaata ttcattatta gattacaatg aaatcttaaa tagagctaaa
    16981 gagatggaga gtaaaggagt gcatagattc tcattggtta caagtggtaa aggtatgtca
    17041 ggaaaggagt ttaataatat tttaaatatc tatgaaggat tgagggaaaa tactaattta
    17101 aaattatgtg catctttagg tattatagat tatgagcaag ctaaaatgtt gaagtcagca
    17161 ggtgtgacta catatcacca caatgttgag acgtgtagag ataattttca taatatatgt
    17221 acaacacaca catataaaga taggataaaa actataaaag atgctaaaaa agctgggcta
    17281 gatgtatgtg taggcggtat aattggaatg aatgagagtg aagaacagag actaaaaatg
    17341 gtttttgaaa tacgagaatt aaatgtaaaa tcatttccaa taaacatttt aaatcctatt
    17401 aagaatacgc caatggaaaa ttatgatgta ttagaaccaa tggaaatact aaaaacaaca
    17461 gcagtattta ggtttataat tcctaatgtg tacataaggt atgctggtgg aaggctatca
    17521 ttaaagggat atgacaaagt tggatttaat gggggagtaa attctgcaat tgttggtgat
    17581 tatttgacaa ctgttggaag tgggattgaa aatgataaaa aaatgattat agagcaagga
    17641 tttgaacttt aataaatact acttaaatta attaatatac ttttagataa ttataaaagt
    17701 atattaattt tttttgcaga ttaatttaaa tattaaaatt gaattataag ttgcaatatt
    17761 ttgaaaaaag ggaaaaatat caaaatttat ataaaatggt tgcaaatggg aaaaggatgt
    17821 gatagtatct aggtaaccgg ttaagtaaaa cggtttccta aattttgggg gtgaacttct
    17881 tgagtataac tataaaagaa attggcgaat tggctggtgt ttctaaaaca actgtgtcaa
    17941 aagtcattaa taataaagat gaaaatataa gtcaggcaac aagagaaaaa attttgaaaa
    18001 taatgaagga aaaaaattat gtaccaaata aattagcaca aagtttagta actaaaaaaa
    18061 ctaatactat agggcttctt ataccagata tacgaaatcc attctttaca gatgtatcaa
    18121 gaggtgtaga agacaaagct aatgaagaag gctacaatat aattttatgt aatacagatg
    18181 aagatgctaa aaaagaatat gaaggaataa gaacactatc agagaggatg atagatggaa
    18241 ttatatttgc agcatcttca aatacaaact ggaaagaagc aaattataaa gatataaaaa
    18301 taccaactgt cttgattgat aagaagataa gtatgaacaa agaaacctta aaaggaattg
    18361 ttaaaataaa taactttgaa ggggcctata tagctacaaa acatttatta gatattggaa
    18421 ataagaaaat aatataccta agtggtccac ttcaaaatga aatagcagta gatagattag
    18481 aaggatataa aaaggctcta atcgagtgta atttaagcta caatcctgct tatgtatttg
    18541 aaggaaaata taagattgaa tggggacaag aatttataaa aaatttagaa aagatagatt
    18601 ttgatgcaat attttgtgca aatgatttga ttgcaatagg tgtcataaga ggtcttaaag
    18661 aaagagggtt aagtatacca aatgatgtaa gtgtcgtggg atttgatgat attcaaacat
    18721 caagtctaat aagcccttct cttaccacag taaaacagcc gtcttatgat ataggatata
    18781 aagccagtga aatattgata aattgtttaa gaggagataa aaaagaatca tttgatgaat
    18841 tgattttcaa accagaatta gtcataagag attcaacaaa agaaagtgaa taacagcacg
    18901 agagacataa atagatatgt aaaggagtaa tgtaatggga aacatagttg tcataggaag
    18961 tgtaaacatg gacatggtat gttctgtaga taaaagacca gaaaaaggag aaacagtatt
    19021 aggtaatagt ttttttacat cacctggagg gaaaggggct aatcaagcta tctcagcttc
    19081 taaactagga gcaaatgtaa aaatgatatc atgcataggg gaagatggct taggagagga
    19141 gttaataaga aattttagaa cgaataaagt tgattatagt ttagtatcca gaaataatca
    19201 caaaagttct ggtgttgctg ttataacatt atgtgaaaat gataatagta ttgttgttgt
    19261 accagggacg aatgagctag tagatataga attaattaaa aagaatgaag aagagataaa
    19321 gaatgcagat atagtattgc tacaattaga gattccatta aaaacaataa attatgtagt
    19381 gaatttctgt tttgaaaata ggattaaggt tttattaaat ccagcaccag cagtaaaact
    19441 aaatgaagat ataatagaaa aagtaactta cttaacacca aatgaacatg aatataagat
    19501 agtttttgac acaaatgaag ggatagaaga agtattaaaa aaatatccaa ataaacttgt
    19561 aataacagaa ggaaaaaatg gagctagatt ttatgatggt gaggaaatca agcatgtatc
    19621 ttgtataagt gttgatgttc aagataccac aggagcagga gatacattta atggagcatt
    19681 ggcagtggct ataacagaag ggaaaaattt atatacagca gtagaatatg cagtagtagt
    19741 atcaggtctt tctgtaacta aactaggtgc acaatctggt atgccttata aagaagatgt
    19801 tgaaaaatat ttaaataata aataaaaatc taatttgttc aaatgtaaaa ctattaaaaa
    19861 tggaggttaa ttatgagagt gagaaaaatt ttatctttag gaattgctgg aatactagca
    19921 ataggaatgt taacagggtg ttcaatggaa ggaccaagta aatcagataa taaaggtggt
    19981 tcagacaaga aagatttaac tattggagta tctacaataa ctcttcaaca tcaatttttt
    20041 atagatattg atgagggaat aaaagaaaaa gctaaggaat taggtgtgaa agttatagta
    20101 aatgacccag accaagatgt agctaagcaa acatcagcaa tagaagattt tatacaacaa
    20161 aatgtagaag gaatgatagt acttggaact gataattcgg ctatagtacc agcagtagaa
    20221 ggagcatttg aaaaaatgcc agtagttaca gtagatgctg tattaaatac tgaaaatatt
    20281 acaagttatg taggaacagt tagttatgat gctggtaaaa aattagggga atacactaaa
    20341 aaatacatag atgaaaagtt aggtggaaag tcagaaatag caatagtgac agatttaaaa
    20401 tctcaaatac aaatgcagag aatagatgga tttaaagatg cgttaaaagg ttcagcaaat
    20461 gttaagatat taaattcaca accaggatat gacagagaag aatctcttaa tacagtagaa
    20521 aacttaattc aatctaatcc agatgtagat ataatatatg caacagctga aaatagtgta
    20581 ctaggagcta aagctgcact tgaatctgca aaaaataagg atgttaagat tgtaggattt
    20641 gacttaactg aagaagcatc aagtggaata acagatggaa ctattcttgc tatgattcaa
    20701 caacaaccta aagagatggg acgtttagct gtagaagcag tagtaaaagc tataaaaggg
    20761 gaaaaggtag aaaagaatat accagtacca gctttacttt atgataagga aaatataaaa
    20821 gactttaaga attagtaaaa taaaatgaga ttatttgaaa gaaatcctat ttaaaaagga
    20881 gtgtcattat gagtaatata attctgaagt taagtaatat tgctaaagaa tttcctggtg
    20941 tcagagcatt agataatgtt aattttgagt tatttcatgg cgaagttcat gcactactgg
    21001 gtgaaaatgg tgctggtaaa tcaacaatga taaagatttt aactggtgca cattcgaaaa
    21061 cttctggaaa atttattttt gaaggcaaag aaatagagaa tatatcccca gatatctcta
    21121 aaaagatagg tataaatgcc atatatcaag aactaacagt ttttgacgaa ttaacagtag
    21181 cacaaaatat ttttatggga aaagaaataa atggcaaagt cttaaccaat gacaaaaaaa
    21241 tgaatgaaga ggctaaaaag attttcgata atatgggaat agatataaat ccaaatagtt
    21301 tagtcaaaga gcttagtata gctcaaaaac aaatggtaga aatagcaaga gttttatcat
    21361 cagaaactaa agtattaata atggatgaac ctacttcttc aataagtaaa aaagagactg
    21421 aaatactttt tagacttata aatgatttaa aagagagtgg agttagtata atatatatat
    21481 cccataggat ggaagaactc tttgagattt gtgacagaat aactataatg cgagatggga
    21541 aaacgatttc gactttgaat accaaagatg tatcgtctga ggaagaatta gttaatttaa
    21601 tgatagatag aaagctagac caatttttcc caaaaagaaa agtagaaata aaagaagaaa
    21661 ttatgcgagt ggaaaatcta actaagaaca atgtttttaa tgatattagc tttaatataa
    21721 gaaaaggtga aatattggga ataggtggac tagttggaag taagagaagt gaaatagtag
    21781 aagctatatt tggacttaga acatatgatt ctggaaaaat atatttaaac aatgaagaag
    21841 taaagtttaa aactccatca gatgcaatag aaaatggact aggattaata acagaagata
    21901 gaaaaggtac tggattgttt ttacaaatga gtgtcaaaga aaacacaact atggctgggt
    21961 taaaaaagat atctaagttt aaatcaatta tagatagaaa aaaggaaaaa gagattttag
    22021 aaaaatacat agaagcttta aagataaaaa caccacatat gaatcaagtt atacaaagtt
    22081 taagtggtgg aaaccaacaa aaagctataa tagcaagatg gcttttatta caaccagata
    22141 tattgattat ggatgaacca accagaggta tagatgtaaa tgctaaggca gagatataca
    22201 atctaatggg agatttagtg gagagtggtg taagtataat aatgatatct tctgaaatac
    22261 cagaattaat atcaatgagt gacagaataa tggttatgag agaaggtcat ataagtggat
    22321 ttttagaagg tgaagaaatg gttgaaaata atgtattaaa attggctttc ggaggtaaaa
    22381 ttaatgagtt caataactaa gcataaagaa gaaaaatctt ctccattatt gacaaaatta
    22441 acaagtgtat ttagagacca agggagtgca gctgtaggac ttgtaataat ttttataata
    22501 atgagtgtag cttcatctaa ctttttaact ttagataatt taattaatgt tggaagacaa
    22561 atatcaataa atgcaatact tgcagtaggt atgacatttg taataattac aggaggaata
    22621 gatttaagtg taggagcagt aattgcttta gtaggtacat tttgggctac aacagtagtg
    22681 aattataatg cacctatatg ggtaggtatg atacttgcat tagcaatagg gacaatatta
    22741 ggagtcataa aaggtgcaat tatttcaaca caaaaactac ctccattcat tgtaacttta
    22801 gccatgttaa cgataataag tggggcaagc tttgtattta caggaggaag acctatatca
    22861 gtaaatacag atgcatttaa gatgctcggt agaggatata ttggaccaat accaatacca
    22921 gttataatta tgattatagt tgtaatagca ggacattttc tattaaaaag aactaatttt
    22981 ggacgtcatg tacatgcagt aggtggaaat gaagaggctg ctagattatg tggagtaaaa
    23041 gtaaataaag ttatagtaaa agtatacgca ctagctggac tactaacagc attagctggg
    23101 ataatactat catcacgttt ggcatcaggt tcaccaactg ttggagatgg agcagaattg
    23161 gatgctatag cagccgttgt gcttggtggt actaatatga tgggtggttc tggttctata
    23221 gtaggtacat gtataggtgt cggaataata ggaatattag gaaatggatt aaacttatta
    23281 agtgtatctt catataatca aatgattata aaaggtttgg taatgttatt tgctatatgg
    23341 ataaataata taaaattaaa aaaatcagct aaatctaaat agtaattaaa ttttagctta
    23401 taaactataa aaattattaa gtttttgtat atatttttat actttaattt gcatacatct
    23461 ttatacattg aatgggaata tgctaagtga aaaagtttac tatggcttaa atagatgaga
    23521 ttagacttga aattttaaat gtaaaaataa atcttaggag gaaatatgaa aaaaattctc
    23581 ttagatacat taaatagtaa aaaacaagaa tacatagatt atttaaaaga acttgtaagt
    23641 ataaagactg aagatgttgg tcatggaata ctaggtggat ttgaaaaaga aggacaggaa
    23701 tatattgaaa aacttgcaaa ttacataggt tttagtgtag atagacaaga aatgagcgaa
    23761 gaactaatta aaaaagcaaa aaatatatat aaagaaggaa atctaggtca caattatcaa
    23821 gatagatata atttaatttg taagtatagt gatgatttac ctggtaagac aattgtattt
    23881 aatggtcatg tagacactat gccaccaggt gatataagta agtggaaata taatccatat
    23941 cgtgctacag aagataatgg aaaactttat ggtcttggaa ctgctgatat gaaatctgga
    24001 cttatagcat caatattagc tgtaaagctt ataaaagata gtggtctaaa tgtacctggt
    24061 aatgtaaaaa taatgtcagt agtagatgaa gaaggtggcg gaaatggtac cataaatgca
    24121 gttatgaatg gtattgatgg agattgttgc ataatttgtg aaccatcaga acaaaactta
    24181 atagttgcac atatgggatt tgtattcttt gaagttgagg ttaaaggtgt gtctcttcac
    24241 tgtggtagta agtgggaggg tgtaaatgca attgagaagg ctatgttgtt gcttcaagat
    24301 ataaaagagt tggaacataa ctggcttatg atatataagc atccactatt accttcacct
    24361 acaataaatt taggtgtaat aaatggtgga acagcaggtt ctactgtgcc agataagtgt
    24421 gtatttaatt tatgtgtaca cttcttgcca aatataatga gttatgaaca agttgtaaat
    24481 gatgtaacaa atgtcataat gacaagggct aatggagatt tatggcttaa agataataaa
    24541 ccaaatataa acatatatca atcagggtta ggttttcaga tggacaagga ttctgatttt
    24601 gtagtgaatg cacataaaat actagaagaa actctaggaa aaaaattaga gataaaaggt
    24661 tcaacagctg gcaatgatgc gagattaatg aaaaatttag ctgaaatacc aacacttata
    24721 ttagggccag gttcaataga acaatgtcat tcaattgatg aatatgttga aattaaggag
    24781 tatttagata gtatacttat gtatgcaagt ctaatattaa acttataaaa gtaggaggaa
    24841 tatataaatg aaaaaagtat taatagtagg ggaatcttgg gtaaaaaata taactcatat
    24901 aaaaggattt gatacgtttg ttacaactca ttatgaagaa gctgtaaagt ggttgaaaga
    24961 agcaatagaa tctggaggat atgagacagt tcatatgcct gcacatgtag cagcagatag
    25021 ttttccgtat aaattagaag agttaaatga gtatgactgt ataatattat ctgatatagg
    25081 ttctaatacg ttcttattat ctaatagtac ttttatagat tgcaatagta atccagatag
    25141 acttgaacta atcaaagagt atgtaaataa tggtggggcg ttaatcatgg taggtggata
    25201 tatgtcattt acaggaatag atgcaaaagc tagatttgga gaaactgcta tcaaagatgt
    25261 attaccaata acaatgatag ataaagatga tagagttgaa aaaccagcag gaataattcc
    25321 agaagttatt gactctgaac atccagtatt aaaaggtata ccaacagaat ggccaaagtt
    25381 tttaggatat aacaaaacag tagctagaga taattgtcct gttttagcaa ctattggagg
    25441 agacccattt gtagctgttg gcgagtttgg aaaaggaaaa tctgctatct ttagttctga
    25501 ctgtgcacct cactggggtc caaaagaatt tactgattgg aaatactata ataaattatg
    25561 ggttaatatg cttgattggt taacatgcta aaaattttat aaaacttgaa aacctcttac
    25621 ttgataaaat gaaacttaca agtcaagagg ttttattgta taaaatggtt gtatggtaga
    25681 aaatattttt aaatcagtta aaattagtca ttttggctga taatcgataa gttattagaa
    25741 acagggaggt ttatataatt aatatggata atttaaataa aaagtttttg atggaatata
    25801 tagatgagat acagggagaa ttaagagata tatcagataa gatatggaaa aatccagaac
    25861 ttcagtataa agaatactat gcttcaaatt tacaaaaaga atgtttaaaa aaacatggtt
    25921 ttagtataga gggattagaa ggtatggata cagcatttgt ggctagttat ggagaaggta
    25981 gaccagttat agcagttttg ggagaatatg atgctttaga tggtttgtct caaaaagtat
    26041 ccactactaa agaacctatt gtagatggtg gtgcaggtca tggatgtgga cataacttac
    26101 ttggtacagg ttcaatagga gctgtaattg cagtaaagga attaatcaaa ctaaaaaagc
    26161 tgaaagggac tataaaatac tatggatgtc cagcagaaga agatttatct ggaaaagtat
    26221 tgatgataaa aaaaggtttt tttgatggaa ttgattgtgc ttttagttgg catccatttg
    26281 atataaatac tccgataaga atcccaacac ttgctaatta ctctgtgaaa tttagatata
    26341 atgggattag tgctcatgca gcacaagctc cttataacgg aagaagtgca cttgatgcag
    26401 tagaacttat gaatataggt tgtaattatt tgagagaaca tatatttgat aattgtagag
    26461 tacactatgt aactactaat ggtggaaaaa tgccaaatat agttcctgat tttgcagaag
    26521 tgtggtatta cataagagga gttaaaatgg agcatgtaag agatgtattt ggtaggattg
    26581 ttgatatagc aaaaggagca gcattaatga ctggtactat tatggaatat gacattataa
    26641 gtggagtata tgactatatt ccaaatacaa tattaacaga tattctatca caaaatatga
    26701 aattagtagg tgtgcaaaac tataatgaag atgactacta ttttgcagat aaattagctg
    26761 agacagtgtc tatagataaa agaagtagtg tttctagtgt attaagtgga aataaggata
    26821 ttactaagat gaatctgcat gatgaagtta cggatgatac atttactcat aataactgta
    26881 tatcattatc attagatatt ggagatgtta gttacataat tcctacagca cagtgttctt
    26941 gttcagtttg gcccattggt atttctgccc atacatggca atcttgtgcc agtgcaggtt
    27001 ctgatatggg atttaaggca atgttattgg catctaaatc tatatcatgt tcaataaatg
    27061 atgtaatgct tgatgaattg gttataaata aagcaaaaaa agaattgaag gatactgtag
    27121 gtagttttaa atatatacca attatttaaa acttaaattg atataagcac aactaacttg
    27181 tatgagttaa tataagtata taatttaata ttatttttaa cccaaccttc taattatttt
    27241 aaatttaaga tacaatgatt agaaggaatt ttttaagttt cttagaatac tgtaaattat
    27301 ataatcttga taaaaagtgt tatactatat ataatctaaa taaaaaatag tacaaaaagg
    27361 agtatttatg tttggatatg ttaaaataaa caaaatggat ttaacattta gagaatatga
    27421 ttattacaaa gcttactatt gtggactatg taaatactta aaaagaaatc atggagaaat
    27481 ctctaggttt tctttgaatt atgatataac atttttaatt gttttattaa cagcagtata
    27541 taacccagag tctataagta cagaggaagt gtgtatagta aatccattta aaaagaaaaa
    27601 ggtaattaca aatgatatta cagaatatgc agcaagtatg aatattcttt taacgtatta
    27661 taaattggaa gataatttaa tggatgataa acgcataaaa gataaattgg catattatat
    27721 atataaaaac aaattaaaat tagcatatga aaagtatcct gaaaaagcag agtatataaa
    27781 acaacaacta aatgaattaa ataagttaga aaaagataaa aatataaata tagatgaagt
    27841 atctagtata tttggaaata taatgggtga agtatttgtc tataaaaaag atgaaaatga
    27901 gagaaactta agaatgatag gttttaatat aggtaagtat atatatctac tagatgccta
    27961 tgaagattta gatgaagatt ttaagaaagg aagatataat ccatttatag agtatattga
    28021 taaaaatgat gagttaaaag aaaaagtaaa aaaaataata gtaacatcat tagggttttt
    28081 agctagggga attgataatc taaatctaaa taaaaatgtt ggaataatag aaaatataat
    28141 ttattctggt gtttatttaa gatatattaa tatattagaa agtagaggtg gaaagaatgt
    28201 acagtaatac ttataataat gaaaatttta tgagagcaag agcattcata gaaaatagtg
    28261 aatttaaaaa agcatatgat tttttaaaaa ctttgactga caaatgtgca gagtggtatt
    28321 atttaactgg cttttctgca atgaacatag gatattatga agaaggtgaa gacttcttaa
    28381 aaagagcaaa atttatggag cctgaaaata gtgaatatag tgatgcactt agaagttata
    28441 cacaatatag aaatgattat agcaataggg ctgacaatta taatagaaga agacgtaatg
    28501 atttagatgg atgttgttgc tgttgctgtg atgattgctg ttgttgtcta ggtgacgatt
    28561 gttgtgaaaa ttgtgctaag ctttggtgtt tagattcatg ttgtgaatgt tttggtggag
    28621 atttaataac ttgttgttag gatgataaat atgagtataa aagttgctta tggaggagtt
    28681 ttattagcat taaatgtgat attgttgact cttacaaata ttattcctgt aaatacattg
    28741 tttattatgg ggttagcatc acttttagta tcaattgtaa taatggaatg gggctttaag
    28801 agtggaatcg ctttttatat aggttctata gttttaggat ttatagtgat ggcaagtaag
    28861 tctcaatgga ttgtatattc acttaccttt ggaatatatg gtattgtaaa atatcttata
    28921 gaaaaagata ggtctatata tattgagtat tttatgaaat tagtatttgc aaatataatg
    28981 atacttatat tgtatttttt attaagaaca atagtttata ttccaataaa catatttatt
    29041 ataggttcat ttgagatagc ctttatagta tatgactatg tttacagttc ttttataggt
    29101 tattacaata ataggttaag aaagatgcta tttaaaaaat aatagttgat ttttatattt
    29161 aattttaatg aaattgtagt ttggataagt gtaaatgata tatctgaata tacattaaag
    29221 cataaagcta aatttaatat attcttagtg caacatataa aagctttgat ttttagtcaa
    29281 agcttttata tgttagatat aaatattaga tataatataa gtttttaaaa tagatagtat
    29341 aaattaaata tccactatat ttacatctgt agatagagaa taaataatat cttttctttc
    29401 tactattatc tcaacatttt tagaaatttc ctcatcaagt gatatttgag ataaaagttc
    29461 ctttgttgga tttattgcta ttggatttcc aactcttttt agcatattta tatcaccatt
    29521 agtatctcca taggcatacg agtttgataa atctaaatca tactttacaa caaaatcatt
    29581 tatagcatta ttcttactta tagaatccca cattggaata actgtgcctg taaatatatt
    29641 attttcaaag acataatcac ttcctagaaa atcggttaca ttatattttt ttgccatttt
    29701 ttcaacaaga aatccagggc taccagatat aaatataact atgtgtcctt gatttagatg
    29761 ccactcaatc cttgaacgtg tgtatttata aactctatct gcttttaatt taattacttg
    29821 gtcacttgta aagttgatac aggttttatc taatcctttt agtgagtcaa cataaaggtc
    29881 acatatttct aatagataat catcataatt accttgtctt ttatcccaat ccataaaagt
    29941 gtctctagca tgtttatacc aatttttttg gtcaattata tcgtatttaa ttaatttttt
    30001 aaaatgttca accataagag agtctctata aagagtacca tctatatcaa aaaaagctgc
    30061 tatatttttc ataagaccac ctcaattaat catttcctta tattatatta taaattgtat
    30121 ctaagttgtt aaaatatatg tataataatt tatatattaa aaaacaagta ttttagagtt
    30181 taaaggatgt gactatatga attttaattt tgcaaaggct acaaattcta gacttatggg
    30241 cagtttaggt cttataataa attggataga tgatgaaaac aatcactttt gtcaatattt
    30301 tttattagat gcagagggat taggattagc agattatgtg agtttaaata acccaacaca
    30361 agaagaagct tatatggaag aagaaagatt gatgggagga tttggttcag atagagttga
    30421 attaacgaag gatgaatctt tatttttagt atcttatttt ggtaataaga atctttatta
    30481 tgataagcta ttgccaggag ataaatgtga gtatattgat attataaaaa actataaaac
    30541 agatttaatt atagaaaaat tatacaataa aatatgtaaa agagttgatg aggaagttga
    30601 atttataaac tatatgacta tgagatttat agcatgggat agagaaagtt taaaatattt
    30661 ttctggaagt gacgagattg caaatatgca tattactaat ataaatggaa cattacttaa
    30721 aaacgtggta agtgataaag gtcaaggcag atatataagt gaagctttat atgaagacaa
    30781 tgatggatat tatatatgta aaattgcttt ttgcataagt aagtgctatg aaactggttt
    30841 tagaattaat tctctattag tgacagataa agaacctatg tatgattttg aggtatttga
    30901 tgagatttct aaaagtgaat ttgtaagtgt ttacagtgta aattcacctg aagaatttgc
    30961 aggagtattt tatagagaaa atccatttct gttaaaaagt aatatgaatg aaggtatatt
    31021 ttttactaga tttaatttta ataatgacca tgtaaaagaa aatgtatata taataaacaa
    31081 tgatatgaaa gctatatatt acttaatggg aaataagttt tttattggta cttataacga
    31141 aaatgattgc aattatatca atgaaataag tcagtctaat tatagtgact atattaaatt
    31201 tgaagagaaa tttttctttg agcaaaatgc attatatgac tttgcagaat caggttcatt
    31261 agattttgat gattttttgg aataaaaaac cactaaaaat ctgattatcc cataaaacac
    31321 tgtatctatc agcatttaca agggagtaaa aacatcaaat tactacgatt ttactacgaa
    31381 tgaatgagcc ttgatacgtc ctattcccta gatttgcaaa gataaggtac agcacatcag
    31441 tattgaaaca agaaaaattg aatgattgat agactgtgga acgcctaaaa tgacgttcct
    31501 tttctatttc cagccgttcc tagtggacgg ctattttatt acccaaaatg aaaggagcat
    31561 taagaattat gaaaaagata ttaaagcgat tatgtacggg cttcctagcc tttgcgacta
    31621 tcgttaccgc cttgccgact accgctgttc atgcagaaag taagcaatac tggacacaat
    31681 cgaatgagcg tgtcggtatc gttgaaaagg taatgaatga cggttctatt ggttcaacct
    31741 ttaatgaggg acatttgacc gttgacggcg aggacgccta ctgtgttgat attaacacag
    31801 attttaaaaa tggatataag accagagctg acgcaagcac acgtatgagt gccgaccaga
    31861 tagccgacgt tgccttatcc attgaatatg ccaaacaata cacagccagc cacggcggtt
    31921 taagcagtaa tcacgcctac cttttaagac agttggttgt ctggcagaga ttgagcgtac
    31981 atcttggctg gcagtgcgat aacgtgcgag cttcctatga tgaaatccca aaggcaacgc
    32041 aggacgaggt attcgcagga gcgaaagcct ttgtcaaaga gaataaagga cgctatgagt
    32101 gtggcggtta tatctactct ggcgaggggc aggaattggg gcaattctgg gcgaacctta
    32161 atgtaggaaa tgccacttta caaaagagtt ccaccaacac cagcattaca gacggtaacg
    32221 gaaattattc aatcgctggt gcgacgtatg gtgtcttttc tgataaggac tgtaaagaac
    32281 agcttgccac tcttacgaca gataacaacg gcaatactga aactgtagaa gtcaaggctg
    32341 gcacagtcta tatcaaagaa ttatccgcac cgactggcta caaggttgat aataccgtgt
    32401 attctctaaa aattgaagct ggtaagacgg caaccttgaa agtagctgat acaccaaaag
    32461 taaccgatac cttgattgag cttttcaaaa ttgatatgga aacacagaaa agcaatccgc
    32521 agggcgacgc tactttagag ggtgcggagt tcacatggaa gtattacgct ggttactaca
    32581 acaaagataa tcttcctgcc aaaccaactc gtacatggac gacaaagaca atcgctgaaa
    32641 aggatagcga cggtacaatc cattacatta cccgtttagc tgacgcttac aaagtagctg
    32701 gcgacagttt ctatatgcag aacgggaaag tcgtactgcc acttggaaca ctgaccgtag
    32761 aagaagtgaa aagtccgaca ggttatttgt tagacggtgc atatatgcag gcaaacggca
    32821 gtgaggaaca aatcaaggga atgtacttaa cacagattac cgaggacggc gaccttgccg
    32881 tactcactgg aagcaatcag ttctccgtat cagacaaggt tatccgtggc ggtgtcaaaa
    32941 tccagaaacg tgatttagaa accaaagaca ccaaagcaca aggcggtgct acctttaagg
    33001 acactggatt tacaatcacg accttaaatg ataacgccgt attggtcgaa ggcaagttat
    33061 acaagaaaaa tgaagtcgta aaaacaatct atgctggttt ggacggtatc gcttctactt
    33121 ctacggactt attaccatac ggtacatatc gtattgatga agtggaaatt ggcgagggct
    33181 atttgattga cggtgcgaag ccgattacct ttacaatcac agaaaatgga aaaatcgtgg
    33241 atttaaccga cgaagcccat tccatttaca atcaaattaa acgtggcgac ttagagggcg
    33301 tgaagattgg agcaggtacg cacaagcgtc ttgctgatgt tccgtttagg atcacaagca
    33361 agacgacggg cgaaagccat attgtcgtaa cggacgataa cggacagttc tctacttctg
    33421 ctgactgggc ttctcacaaa cataacacca acgagggcaa gaccagtgag gacggtgtat
    33481 ggtttggtac ttctgaacca gacgacagca aaggtgcgtt attatatgat acttacacca
    33541 ttgaagaatt aagatgttct tctaataaag gatttactct tatcccacct tttgagattg
    33601 tgatttccag aaacaaagta accgttgatt taggaacatt gaccgacgaa tacgaaaaag
    33661 aaatctcaat ccacaccaca gcgaccagca aagacggcga gaagtcaatc attgcaggca
    33721 aagaggtaac aattattgat accgtcaaat tagacggact tacaaaaggg acaaagtatc
    33781 agttaaaagg ctggcaaatg gttaaggacg aaaatgccga acttatcatt gacggcaagc
    33841 gtgtagagaa cgactatacc tttgttgctg atgatgaaga aatgaaagtt gagattgcct
    33901 acacattcaa tgcgtctgct ctaggtggca agaaccttgt aacttttgaa gaattgtacg
    33961 atttaagcaa tccaaaagaa cctgtcaagg tggcagaaca caaggacatt gaggacgacg
    34021 ggcaaaccgt attgattacc gagcgtatca tcaagataca taccacagcg acctttgagg
    34081 acggcaagaa agaaatcgaa gtcgacaaag acgtaacgat tgttgatacc gttactttag
    34141 agggcttgga agtcggcaca aagtatcagc ttgtgggctg gcagatgtta caagaagaaa
    34201 atgcggagct tatcatcaat tgcaaacgtg tagagaatga ctataccttt atcgctgata
    34261 gcgaaaacat ggaaatacag atttccttta cattcaacgc ttccgagctt ggcggtcaac
    34321 agcttgtaac ctttgaagaa ttatatgatg taagcaatcc agacgaaccg aaaaaggttg
    34381 cggagcataa ggacattgtg gacgaggggc agacagtaac aatcaaggaa gtaccagacg
    34441 ttcccgaaga accagagaaa ccagaaacac cgacgacgcc cgatacgcca accagaaccg
    34501 acagtcccca aacgggcgac agtacaaacc ttatggcatt tatcgtgatg ttgattgctt
    34561 ctgctggcag tcttgcaggt acatacttct acaaacgccg tcgcatgaaa aaatcatagg
    34621 acggtaaatg tatgagaaaa gaaaaatcac gttctccacc gttcccgtgt cggcagacta
    34681 tcgcttattc tggcttgtct gcctaccacc tgcaagaaca cggatagtca agggtgcgta
    34741 aacatacatt ttacccttta ctatctgggg gcttgctggt atttcccata ccgccagaat
    34801 aagaacctat caaaataaat gtaaagaaag aaacgaggta aaacactatg gaattaaaat
    34861 atgttgtgcc gaacatggaa aagacattcg gcaatttgga atttgcagga gaaagcaagg
    34921 tggaacagca acgtattaac ggacgctata cacccgtatc aagaagctac aacttgtatt
    34981 ccgacgtaca gcgtgccgat gatattatcg taaccattcc tgccaaagct ggcgagaaac
    35041 attttaagcc agaacagaaa atcaagttga ttaacccacg cattaccgca gagggctaca
    35101 atatccgtgg gcgtggcttt acaaactata tcttactggc tgatgatatg tttccagtgg
    35161 aaagtaaata agggggtatt cattatgaga ttagcaaatg gaattgtatt agataaagaa
    35221 aagacattcg gtgtgttgaa gttctctgcc cttagacatg aggtgcgtat ggaaaatgag
    35281 gacggttcta caagtgaaga aatcaagaga agaacctatg acctcaaatg cagtgtgcag
    35341 gaacgtatga tacaagtgtc tattcctgct gatgtagcgg tcaaggatta tccctacaat
    35401 gccgaggtgg agcttatcaa tccgatagcc gatacggtag caaatgccaa ctttagaggg
    35461 gctgatgtgg actggtatat caaggctgat gatattatct tgaagaacaa aggcaaccag
    35521 ccagcaggaa atccacagaa caacaatccg cagggacagc cgaagaaata aggtaatgaa
    35581 ttagattttc attgtagcgg atatatggag ttgatataat gtagatataa aaagaaagga
    35641 gtagcccatt atgaaaatgc caaaagaaaa tattgatact gctatgtttg ctccttgtgg
    35701 aatgaattgt cttgtctgct acaagcattg ctaccataaa aaaccatgtg caggttgttt
    35761 gaatagcgat aaaggaaaac ctgagcattg ccgtaaatgt aaaataaagg actgtatcaa
    35821 agataaggga ctatcttact gttttgaatg ttccgattat ccttgtaaat tgattaaaaa
    35881 tcttgaaaaa agctataaca aaaggtatca agcaagcctt atggaaaaca gcgatactgt
    35941 acgacagcat ggtttagaaa tctttatgga aaaacagaaa gaaaaataca cttgttctaa
    36001 atgtggcggt atcatttcaa ttcatgatag agagtgtagc gaatgtcaag aaaaaatgta
    36061 ataatcatac ttcatataat tgcggttagt ctatacgatt gaccgctttt tccatgcaaa
    36121 gaaaggagtg atttcatgcg aacgattttg aacaaaggac accgtatcag agccagcgac
    36181 aagagccttg tctaccgctt ttcattgagt atgcttctat ttttgttcat agcggttatc
    36241 ctgctactga atatgaaaca gctcatgcgt accgattggg agcatatcag cttgttagag
    36301 aacggcttga cgctttcccc ttacaacttc ataaccatat tgatagcgac tggtgtttgt
    36361 gcattggtcg cttttctgta ttaccgcttc tgctatgacc gtttcaaaca gttattgcac
    36421 cgtcaaaagc tggcacgaat gatactggaa aacaagtggt atgaagccga taccgtacaa
    36481 gacagcggtt tttttactga cctgcaaagc agatcaaggg aaaaaatcgt ctggtttcca
    36541 aagatttact atcaaatgga aaaaggattg cttcatatcc gctgtgaaat tacgctgggg
    36601 aaatatcaag accagctctt acgattagag gataaattgg aaagtggctt gtactgtgaa
    36661 ctgaccgaca agaccttgca tgacggctac attgaataca cgcttttgta tgatatgata
    36721 gcaaaccgta tttctattga tgaagtgaaa gcagaaaacg gctgtcttag gctgatgaaa
    36781 aatcttgtct gggaatatga cgcactccct cacgctctga tagctggtgg aactggtggc
    36841 ggtaaaactt actttctgct gacaatcatt gaagcattgt tacagaccaa cgccgagctt
    36901 tacatcttag acccgaagaa cgctgacctt gcggacttgg gaacagttat gccaaatgtc
    36961 tatcatacga aagaagaaat gattgattgt gtcaatgcct tttatgacgg tatggtggca
    37021 cgaagcgaag aaatgaaaca gcacccgaag tataagacgg gcgaaaacta cgcttatctg
    37081 ggactaccgc cctgctttct aatctttgat gaatatgtgg cgttttttga aatgctagca
    37141 acaaaggaaa gcatgagctt acttagccag ctaaagaaaa tcgttatgtt aggacgacaa
    37201 gcaggctatt ttctgattgt cgcctgccag cgtccagacg caaagtattt ttcagacggg
    37261 ataagggata acttcaactt ccgtgtaggg cttggacgta tcagcgaatt aggttacggt
    37321 atgctgttcg gttcagatgt gaaaaagcag tttttccaga agcgtatcaa agggcgtggc
    37381 tactgtgatg tagggacaag tgttatcagc gagttttaca ctccccttgt acccaaaggg
    37441 catgacttct tacagacaat cggctctcta gcatacgcta ggcaggacgg gacggcgacg
    37501 tgcgaagcga aaggagacgg cacggactag ccgttgctgg tgtggcggta gccacgccag
    37561 cagacatcag cccctcatta tctaacagag gggcacaatt acgctggaaa ctggttcaaa
    37621 aaccttgaaa agtccgctag gaataagggg tttcttagtt ttcagatagt tgtgataatc
    37681 acttgaaaat atcacaaaat cacaacaata tcacgattgg gggtatgaca actgaatgat
    37741 actgattttc tgaacacctt gaaagcaaaa cgcactgact acggcgtatc gcagacaagg
    37801 cttgcaatca tggctggtat cagccgtgaa catttgagcc gtatcgaagc tggcaaggta
    37861 gcactgaccg aggacatgaa gcacaaacta ctggaagctg tggaaaaatt caatcccgaa
    37921 gctcccatgt tcctgctctt tgattatgtg cgtatccgat ttcccacact ggatatacag
    37981 cacgttatca aggacattct aaagctgaat gtagactata tgcttcacga agatttcggg
    38041 cattacaagt acaccgagca ttactatatc ggggacgtgt tcgtttatac ttcacaagac
    38101 aaggaaaaag gtgtcctgct ggaactgaaa ggcaaaggct gtcgccagtt tgaaagctac
    38161 ctgctggcac aggagcgaag ctggtatgac ttcctcatgg acgcattagt taatggcggt
    38221 gtgatgaagc gtatcgacct agctatcaac gacagaacgg gcttactgga tattccagaa
    38281 ctgatagaga aatgcaagaa cgaggaatgt atttctaaat ttcgttcttt caagaactat
    38341 ggttctgggg agctggtaaa gcacaacgaa gtcaacaagg acggcatggg acacacgctt
    38401 tatattggtt catttaccag tgaagtctac ttctgtgtct atgaaaagaa ttatgaacaa
    38461 tcctcaaaat tgggaatacc gattgaggaa gtccccatta aaaaccgatt tgagatacgt
    38521 ttgaaaaatg aacgtgccta ttatgccgtg agagaactgc ttacccacta tgacgcagag
    38581 ctgacggcat tttctattat caatcagtat atccgctttg ccgataagga agtaggcaag
    38641 cgaaaaagcg actggaaaac caacgtccgc tggtcttggt tcattggcga gggacgaccg
    38701 cccgtgaagc tgacgacaaa gccagagcct tatactctgc aaaggacgct gaactggcta
    38761 caaaggcagg ttgccccgac tttgaaaatg ctgaaacaga tagacgcagg caatcagacc
    38821 gactatctca aaactattga acagcaggca aaactgacgg acaagcacaa gcagatcgtg
    38881 aagcaacaga cggcttcggt ggacgaactg ataaaacaag aaaaggagtg attgatgatg
    38941 atatgggaat tgattaagga cttactgctg gtatcacttg gcatgggtat cggcgtggtt
    39001 ctgatgtgta ttatgagtgt cggaaaggaa gctgaccgac acatgattga attaaaggaa
    39061 agcgaggaaa aataaatgaa tttcggacag aatttgtaca actggttttt aagcaacgcc
    39121 cagagcttag tgcttatggc gattgtggtt attggtattt acttagggtt taaacgtgag
    39181 ttttcaaaac ttatcggctt cttggtggtt gccttagttg ctgttggatt ggtattcaat
    39241 gcaggcggtg tcaaagatgt actcttagag ctgttcaata agattatcgg agcatagctg
    39301 tactttcaca taactgtttg cggacacgca aacatacctt ttcccactta ggagtaagct
    39361 aagaggagga atggaatggt acacagataa aaacaacagc attacgaatt ttattgattg
    39421 acttgaatat agctgatata atgtgcatag gaagaaagat aaatttggag tgatgaacta
    39481 tgaaattatt tgattggggc ggaagagaat aaaaatatac ttctttgatg aattagataa
    39541 caaaaattta aggagaacaa tgaagtatga ataaattaat tttaagaccg attatttctg
    39601 ttgaagataa aaatatattt ataagcgaaa ttcaagaagc gtttcaaaat gcttatataa
    39661 aagaatttgg agaatttgag aaaacaattc ttcccacaaa tgatattgaa gaatcgttta
    39721 acgaaagagg tgctgaggct tatgtagcag aaattgatgg agaaagagtt ggtggtgcaa
    39781 taattattat agataataaa accaactgta attcacttga tttgttatat gtgaaagcaa
    39841 actcgcaaaa tacaggaaat ggatttaaaa tatggaaagc aattgagaag ttacaccctg
    39901 aaacaagaat ttgggaaacg catactccat atttcgataa aagaaacatt catttttatg
    39961 taaatcgctg tgggttcaaa attgtagaat tttttaatcc taagcataaa gattcacacc
    40021 aaacgagtga aaccgcaagc aacattccag aagaaaacaa ttatttcttt agatttgaaa
    40081 aagaaatgag ttaaataatt ccatatctat tttcacaagc agttagtcta tatgattaac
    40141 tgcttttttc atacctaaat ttaagattgg agtgattgct tgaaagatat attttcggat
    40201 atgcaggcaa gtatcagttg tccctacatt tcagacttgc cacatcataa gcgtatagtg
    40261 tggcaggaaa tgaaacgact gaaccttgcc gattatccgc agaaacaatt agaagatttt
    40321 acacgctatg tctttggtgt tccttatacc agcatagcgg agacattaca gaaaggacgt
    40381 gaaaacctat gaatgaaatg cgtgtctgta tcgaaagccg actacccact tctgaagaag
    40441 cctgttccgc atggttcacg tttcccgttg acgaggaaga atttgaagaa cggataggcg
    40501 ttcctatcga cagtgaagat tatcgtatca cagaaatgga actgcccttt gctgatgaag
    40561 tcggcgaaga tacgactatt gaaaaactga atgaccttta ccatatcttt gaaagtctgc
    40621 cacatgattt acaagaggac tacggagagc tgacgtgtta ctttaccagc cttgacgaac
    40681 tgcaccagca ccgccatgat gtgatacatt attcatggtg taaaaacatg gctgacgttg
    40741 caaggcattt gttagacaat gaccctgctt tttctgccat tgaggaacgc ctgacccgtt
    40801 actttgatta cgaagcctac ggacagtatc ttgatgataa cggaaatttc atagaaacag
    40861 accacggtat ctatgaactg ccgtagaaat gaggtgttgc tatggtagag gatatgcgtg
    40921 tatatatcgc taatctagga aaatacaacg aggggtatct ggtcggcgac tggttctctt
    40981 ttccgattga tgaagaagat gttgccgagc gtatcggctt gaatgaacgg tacgaagaat
    41041 acgctgtaca tgatacggaa aactttccca ttgagattgg tgaatatatt tcgattgaag
    41101 aactcaatga aatgtttgaa atgattgaag aattacccga ctacatcacg gacgagctgg
    41161 acgagtttat ctctcattac ggcagtctgg aagaagtata cgaccataag gacgacgtgt
    41221 attgctattc cgattgtgaa accatgaccg acgttgctta ttacttcata gatgaaatgc
    41281 aaatgttagg ggaaatcccc tcacagctac agaactatat cgactatgaa gcatacggca
    41341 gggatttatc cattgaggga acttttattg aaacaagcta cggtatgtgt gagataccgt
    41401 ggtgagaagc tggaagatca gcgacaagca ttgttgcttc tgacagcttt ttctattggg
    41461 gacagtctga aaaacggctg tccttttcta ttatgcgaaa ggagttgaaa tgaaaacgtg
    41521 aaaaagatta aaagctacac gggtatctgg aacgtggaaa aagtcttgta tgcaatcaat
    41581 gactttaacc tgccctttcc cgttaccttt acacagatta catggtttgt gataaccgag
    41641 tttatcatca ttctgtttgg cgacttaccg cccttatcca tgattgaggg ggcattttta
    41701 aaatacttcg gtattcccgt ggctcttaca tggttcatgt cgcaaaagac ctttgacggc
    41761 aagaagccgt acagcttttt gaaatcacag ataacctttg ccttacgacc aaagattact
    41821 tatgcaggaa aagccgtgaa actggataag caggtactac atgaaactat cacggcagta
    41881 aggagtgtga gctatgttcc cgattaaata tatcgacaat aaccttgtct ggaacaagga
    41941 caatgaggtg ttcgcctact atgagctgat accgtacaac tattcttttc tatccgctga
    42001 acagaaattc attgtgcatg acagcttccg acagttgatt gcacagtccc gtgagggcaa
    42061 gatacacgcc ttgcagattg ccacggaaag ctcaatccgt agcatacaag agcaatcgaa
    42121 aaagctggta acgggacgat tgaaagacgt tgcctatcag aagatagacg aacagaccga
    42181 agcgttggta agcatgattg gggacaatca agtagactac cgcttttttc ttggcttcaa
    42241 gctcatggta acggaagaac aattcaattt gaagaacatg aaaaaatcgg cgtggctgac
    42301 gttcaaagaa tttatccatg aagtgaacca cacattgatg aatgactttg tttccatgcc
    42361 aaatgatgaa atcaaccgct atctgaaaat ggaaaagctg ttagaaaaca aaatcagccg
    42421 acgcttcaag gtgcgacgct tggaaacaaa cgacttcggg tatctgattg aacatcttta
    42481 cggcagggac ggtatcgcct atgaagatta tgagtattta cttccaaaga agaagttgaa
    42541 aaaagaaaca ctgataaagc actatgactt gatacgtccg acccgttgcc ttgtggaaga
    42601 aagccagcga catttacgct tggagcatga ggacagcgaa agctacgttt cctattttac
    42661 tgttaatgcg attgtcgggg aactggattt tccgtcctct gaaatcttct atttccagca
    42721 acagcagttt atctttcccg ttgatacgtc catgaatgta gaaatcgtgg aaaatagaaa
    42781 agcattatcg acagtcagaa ataaaaagaa agaattgaaa gatttagaca atcacgccta
    42841 ccagtcgggc agtgaaacca gttccaacgt ggtggacgca ctggacagtg tagacgagct
    42901 ggaaacggat ttagaccagt ccaaagaaag tatgtataag ctctcgtatg ttatccgtgt
    42961 atctgctccc gaccttgacg aactgaaacg ccgttgcgat gaagtaaagg acttctacga
    43021 cgatttgaac gtcaagctgg tacgtcctgc tggcgatatg ctggggcttc actctgaatt
    43081 tttaccagcc agcaagcgat acatcaatga ctatgtgcag tatgtcaaaa gcgattttct
    43141 ggcagggctt gggttcggtg caacacagca gttaggggaa aacataggta tctatatcgg
    43201 gtattccgtc gatacgggac gtaatgtata tttacaaccg tcgttagctt cacaaggtat
    43261 caaaggtacg gttactaatg cccttgcttc tgcctttgta ggaagtcttg gcggtggaaa
    43321 atcattctgt aacaacctgc ttgtctatta ctctgtgctg tttggcggtc aggcggtaat
    43381 cttagacccg aaaagtgagc gtggcaactg gaaagaaacc ctgccagaaa tcgcccatga
    43441 aatcaatatc gtgaacctaa ccagcgacag agaaaatgca gggcttcttg acccgttcgt
    43501 gattatgcag aatgtgaaag acgctgaaag tctggcaatc gacattctca cattccttac
    43561 gggcatttca tcaagggacg gagaaaaatt ccccgtactt agaaaggcgg tgcgtgctgt
    43621 tacccagagc gaccagcgag ggttgctcca tgtgattgag gaattaagaa aagaagatac
    43681 acctatctca tgcaatattg ccgaccatat cgacagtttc acggactatg actttgcaca
    43741 tctgctgttc tctgacggta cagtacaaaa tgcaatcagt ttagacaacc agctcaatat
    43801 cattcaagta gccgacttgg tactgcccga taaggacacg gcctttgagg aatacacgac
    43861 cattgaatta ctgtctgttt ccatgctgat tgttatatct acctttgcct tagatttcat
    43921 tcacagcgat aggtcaatct ttaaaatcgt ggacttagat gaagcatggg cgttcttaaa
    43981 tgtggcacaa ggcgaaacgc tctctaacaa gctggtgcgt gctggtcgtg ctatgaacgc
    44041 aggtgtctat tttgttacac agtcctctgg cgacgtgtca aaggaaagtc tgaaaaacaa
    44101 tatcggcttg aagtttgcct ttagaagcac cgatataaac gagattaagc agacccttga
    44161 atttttcagc attgacaaag aggacgagaa caaccagaag cgacttcgtg atttggaaaa
    44221 cggacaatgc ctacttcaag acctttacgg acgtgtgggc gtggttcaga tacacccagt
    44281 ttttgaagaa ttactgcacg cctttgatac cagaccgccg atacagagaa atgaggtgga
    44341 gtgatgaaag aaaggataca aggtgcgttc acaagaaaaa agatacttca cgttctcaaa
    44401 atggctctgt ttgtcgtggc actgttcctt atcctgcttt cactcttggg aacggtggta
    44461 cacgcaacgg gacttgtgga cgatactatc aatacggaaa acctttattc aaaatatccg
    44521 ctgtcgaatt atcagcttga tttctatgtg gataatagct ggtcttggct tccgtggaac
    44581 tggctggacg ggattggaaa aagtgtgcaa tacgggcttt actgtattac caactttgtc
    44641 tggactatca gcttatatct aagcaatgct acgggctatg tagtgcagga agcctataag
    44701 ctggatttca tcaacgatat ggcagacagt atcggtaaaa gcatacagac ccttgcaggc
    44761 gttacgcaga acggcttttc cacttctgga ttttatgtgg gatttcttct gctgattatc
    44821 ttagtggtgg gtatttatgt tgcctatacg ggactgataa aaagagaaac cagcaaggca
    44881 cttcacgccg ttatcaactt tgtggtggtg tttcttttat cggcttcctt tatcgcctac
    44941 gctcccgact acatcaagaa agtcaatgag ttttccagtg atataagcac tgcttcactg
    45001 gacttgggaa caaaaatcat gcttcccgac agcgacagca agggcaagga cagcgtggac
    45061 ttgataaggg acagcctatt ttccttacaa gtacaacagc cgtggctact gcttcaattc
    45121 ggtaattccg atatagagga aatcggctct gaccgtgtgg aagctctggt atcggcaagt
    45181 ccagaggacg aggacggcga aacaagggaa aatgtcgtca agaccgagat tgaggacaac
    45241 gacaacaaca atctgacaat accgcaggtc gtgaaccgtt taggcatggt gttcttcctg
    45301 cttatattca acttgggtat cacaatattt gtatttctgc ttacgggtat gatgttgttc
    45361 agccaaatac tttttattat ctttgctatg tttctaccta tcagctttct gctttccatg
    45421 ataccgagct atgaaagcat ggcaaaacaa gccatagtcc gtgtgtttaa tacgattatg
    45481 acaagggcag gtattactct aattgtcacg gtagccttta gtatttccag tatgttctac
    45541 aacatatcga cggactaccc gttctttatg gtggcgttct tgcagatagt gtgttttgca
    45601 ggtatctaca tgaagctggg cgatttaatg agtatgttct ctttaaacgc tggcgacagt
    45661 caaagcatgg gacggagaat attccgcaga ccgtatctgt tcatgcgaca tagggctaga
    45721 cgtatggaac ataggcttgc aagagctgtt agtgctggtg gtgtcgctgg tgcggtggct
    45781 ggtggtgtcg ttgccagttc aaaatct
//
LOCUS       DACTZW010000028        44109 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.028, whole genome shotgun sequence.
ACCESSION   DACTZW010000028 DACTZW010000000
VERSION     DACTZW010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 44109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44109
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.028"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(33..689)
                     /locus_tag="JAM15_08040"
     CDS             complement(33..689)
                     /locus_tag="JAM15_08040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798198.1"
                     /translation="MKKGDFIWSGVLICIIAVLAIPSSREVFMEATGAHPYIGGFLKF
                     AVLATMGDLLGARILYKDWKIPVGVFYRAIVWGIIGVVTTYGMSIYSSGVGQAQVDGM
                     LPFEGIAFANALFKSATMNILMSPTVFLFHKVMDCFIDKKYEVGKGIKVKLKDVVNIV
                     DWNAYLGFSVLKTIPFFWIPCHTIVFLFPAEYRVIASAFASIALGLILALANKSKVAV
                     "
     gene            complement(1964..2374)
                     /locus_tag="JAM15_08045"
     CDS             complement(1964..2374)
                     /locus_tag="JAM15_08045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798199.1"
                     /translation="MKIKKSLISAMMVSAMVLGGTGAVFANGNDSSNIALPKLESLIK
                     SGITDPTELEKYGVEHYTYEEYAKHIQELKDYAKDPNAVKDVSQKDLEETIKKMEQEL
                     EKIKTEGLKIMKPITIENEDGSQISIAYNYAAID"
     gene            complement(2590..3972)
                     /locus_tag="JAM15_08050"
     CDS             complement(2590..3972)
                     /locus_tag="JAM15_08050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HAT6798200.1"
                     /translation="MFIKLLEMSFTSGVLLLIVIFIRACLFKKLPKKVFVLLWLIVLF
                     KLLIPVSLNSGFSIYSIIESTFDVELGNTSTENYTLKKASDSTGKNNSDEFEIMSNIE
                     NIMMLEMLGILSFIVTIMFSILLCFRYFKIINLFKTSIHIKNHEFIKKWMCKNSRFRR
                     FIVCISEFTRTPLTSGILKPRIILPKQMNYANNQTLDFVLTHEMVHINSFDNLLKLFM
                     LVALVAHWFNPLVWVMFFLLNKDIEFSCDEKVMSILGEEYRADYATTLITLAEENNPF
                     SMTICSGFGKTKIEKRIVNIMKFKKSTYVTFLVSTVLVCGTGLVFATENKEINEVESF
                     GLTKNEQSDKSGFSISSKSTDLYSPKVESDILVSKAKSDGETHFSTAKVSVIEFREHE
                     ESSMSKVTNSENSEETYVNKSSNSKDILYTDSGEVSIEQSNYNDNRFVISRKGNLLAV
                     NKEQYRTWIE"
     gene            complement(3983..4342)
                     /locus_tag="JAM15_08055"
     CDS             complement(3983..4342)
                     /locus_tag="JAM15_08055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HAT6798201.1"
                     /translation="MEIKLFDSELKVMEVLWERGESKAGELVKILKEETGWNRNTTYT
                     VIKKLVSKGAIERIEPNFVCKALISKEEVQKQETETLINKMFGGSSEKFLSAFINKEN
                     LSSDEITKLKQIVEKLK"
     gene            complement(4547..5326)
                     /locus_tag="JAM15_08060"
     CDS             complement(4547..5326)
                     /locus_tag="JAM15_08060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HAT6798202.1"
                     /translation="MVSRQELKRVSKAQLSGNWGICAISMAVYIALIVLISIVGLPFE
                     PLTTIVVAVIAFCVSAGFTCMFLKITKDEKVKIGDIFVSGRIYLRSFGFYLFESIIVY
                     IYSFIITIIGAFLSFGVLLTSGAIEYLSSDNVGIGTIISTGITLVLIILVLMLPVYIL
                     LLYVSQATFLICEDKDNMGVFKSMGASLDMMKGNVLKLFVLNFSFIGWYILSIATLGI
                     GLLWLIPYVGVTNCNFYRQLVKENPDVEDILLDKEKSYTMY"
     gene            complement(5787..6398)
                     /locus_tag="JAM15_08065"
     CDS             complement(5787..6398)
                     /locus_tag="JAM15_08065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HAT6798203.1"
                     /translation="MKMVKKLILSTIMALVLVLTIGCSNAEEKVKSNFEANLAALEMY
                     KYDEKGISDALTEAEYKQIQTYNSKDKVSMIAQLTPLYGKENAEKIYETIVKLIQGVE
                     KTVTVESSSKDKITLKVVSKALDTSKVMSEANTLVKSYVTDEKNYDKKEKEVQDDMTK
                     MIIDLYNKKPTKEVTTMITYTKKDGKWQPPSNIQKLCEGIYTI"
     gene            complement(6490..7479)
                     /locus_tag="JAM15_08070"
     CDS             complement(6490..7479)
                     /locus_tag="JAM15_08070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HAT6798204.1"
                     /translation="MLLLKKDDIKKVFTMRDAIEADKEAFRIYCEGKSVNPLRTNISV
                     PSQDASMLFMPGYVEELGCGGIKIVSVFPKNAQKGKPVIPATVLLLDGETGEVSAVLD
                     GTYVTQIRTGAASGAAIDVLAKKDSKIGALIGLGGQGEPQLEAMIEARNLDEVRVFSR
                     NRESREKFAEEMNLKLSKYNTKIVAVESSDEAIDNADVIVLATPSKQPVLNGNLVKKG
                     ALISAVGSYMPDMQELCPNCLTRASKIFFESTDAVLSESGDILIPLKEGKISKDDFSG
                     DLGNVINGTIPGREDDDEIIVFKTVGIGVQDVVTAKRIYDKAKENGIGIDWKW"
     gene            complement(7546..8409)
                     /locus_tag="JAM15_08075"
     CDS             complement(7546..8409)
                     /locus_tag="JAM15_08075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HAT6798205.1"
                     /translation="MKFFKVDTKAKVLRYVFVLTLTIMAVLAIKHDYKYNNLRKDASI
                     NLNSNKEAVTVMSNQSLPKGNTNSKQTLSVSTIGSKTIVKNDEYLESTINMPVITNSN
                     KIVERSTNDKIKNDIFEFYNKSYKEAKQYLKDNPDEKNKFVANVDFELKKNTDSALSI
                     KVRYYTYSGGAHGFYQDIAYNVDMRTGKFLELMDLFKDNTKYKEVIDEEIKRQIAELE
                     KKDEENIGIYNFKGIKENQNFYLQDENLVVYFDLYDITPYAAGIPEFSINKALISSML
                     KPEYVDLFDLK"
     gene            complement(8515..9111)
                     /locus_tag="JAM15_08080"
     CDS             complement(8515..9111)
                     /locus_tag="JAM15_08080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheB"
                     /protein_id="HAT6798206.1"
                     /translation="MERFNNMVIAIGASVGGTEAILEIIKDLPKSTPGIVVVQHMPAI
                     FTYMYAQRLDKQCIMNVREAKNNDRVEQGNVLIAPGGYQMKLCTDKQGYYVTCEKGER
                     ISGHCPSVDVLFDSVAEVEGKNSIGIILTGMGYDGANGLLKMKENGSFTIGQDENSCI
                     VYGMPMVAFDRGSVMLQLPLGEISNCLIRHINILKQKD"
     gene            complement(9151..9954)
                     /locus_tag="JAM15_08085"
     CDS             complement(9151..9954)
                     /locus_tag="JAM15_08085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate O-methyltransferase CheR"
                     /protein_id="HAT6798207.1"
                     /translation="MIKLTDEEFIVLVNHVKKEYGIDLSKKRALIEGRLYNTMIEKKL
                     SSFSQYMNLLFKDKTGNEAINLINRLSTNHTFFMREPQHFEFIQNSILPFWEENNKIR
                     NINIWSAGCSSGEEAYSIAMTLDDYFGYNKELWNIKIIATDISTNSLEKAKRGIYIES
                     NVNNVPELWKKKYFIDNKDGTFKICDKIRKSVIFKPFNLMNDFSYQHFDLIFCRNVMI
                     YFDLKTREELINKFYNATKKDSFLFVGHAEVINRSSTKYKYVKPAIYKR"
     gene            complement(9990..10430)
                     /locus_tag="JAM15_08090"
     CDS             complement(9990..10430)
                     /locus_tag="JAM15_08090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HAT6798208.1"
                     /translation="MAKDEIIKQVLTFYVNDVIYGIELENVIETIRFQSITYVPCLPT
                     YISGVINLRGRIIPVINMHIKYNLPKADYNERTCIIITKVDEYQVGIIVDKVVDVIHI
                     ENVNLLETTNSNNTNINKDIKEIAKVEDNSILILDIRKFLINSM"
     gene            complement(10443..12545)
                     /locus_tag="JAM15_08095"
     CDS             complement(10443..12545)
                     /locus_tag="JAM15_08095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheA"
                     /protein_id="HAT6798209.1"
                     /translation="MRQMLDMFIFETSLLLEQLDEIMIQIEKEKVFTHNNINETFRIM
                     HTIKGSASMMGLDNISALAHSVEDLFYAIREGKIEVLDNDLLFDLVFQSLDFIRRDID
                     ELQSRGCISSDYSNFIEGIEEYVSTLELSSSMKSKDNANLESTDEKEAIDSNFEYKED
                     SDVVKIIFEQGCMMENVRAFMLVFELRDYCEFIDFYPKDVETNAESTEYIKSYGFYIQ
                     FVAKEDKAIVYKTIEDNLYVKEYINISKKEIEMKSTSNNDAVENKLKDNNKVSKSYQN
                     NYTEDEIQEDVLNEKTDMEKDSLSEENEHLPISKQSIMSVNLEKLDLLQNIVGEIVIM
                     ESMVVNSVNSTGVDIDNFNKATRQLHKLTDELQDIVMSMRMIQIAGVFQKMHRIVRDM
                     NKKLDKNVELITIGAETEVDKNVIDNLAEPFMHLIRNAMDHAIEPIEERIAKGKEEVG
                     KIVLSAENLGGEAVISISDDGRGIMRDKILAKAKEQGLLKHQINEYTDDEVNSLIMTP
                     GFSTKESITEFSGRGVGMDIVRKSIEKVGGSIEVKSKQDEGTTFTIKIPLTLSIVEGM
                     KFKVGDSLFTLPISSIRRTFKLTDLNQIITEGNKTELITIYGACIPIIRLHKIYNIQT
                     KVTNLMHGNMIIIENEHKAVCIFVDEIIGNQQVVVKPFPVYFNRFNIKNKGLSGCTIL
                     GDGSISLIIDADSIIEIY"
     gene            complement(12664..14367)
                     /locus_tag="JAM15_08100"
     CDS             complement(12664..14367)
                     /locus_tag="JAM15_08100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing protein"
                     /protein_id="HAT6798210.1"
                     /translation="MKREVKLSKLAIVLLIIIVLAVLAGIFSSISSYKAFEKVEKSIN
                     DMNNLRTQSQYIKDTTREISDVLRRYVFTGEKKNKDIYEKELYGKTRESALNKLEKIG
                     LTKSESNKILEAKEISDSLVPTEQSAIKAVESNDKSKAQSIIFGSDYINSQEKMDSLI
                     NEFQEDIVTRSNSKIVEVKKELQSLILRTIFILSLLIILTIIEYTVIKLKIVIPINKV
                     EKHFSRIASGDLRTSIDVEESKSEIGLLVSSVKKMQSMLLNYIDLIDSTLTSIAKGDL
                     RVEIDQEFIGDFKSIKISLESIINSFNGDFSEINLSAEQVASASEQVAAGAQALSQGA
                     TEQASSVEELASTINEISDGIKKCADSASLACEVSDQSASQVGFGSRCMDDMMTSMGE
                     ISEKSSEISKIIKTIDEIAFQTNILALNAAVEAARAGQYGRGFAVVADEVRSLAGKSA
                     KAAQNTAILIEEAIKTVENGVRIAKETANALDLVVNGVEKTTNYINGISSAVHSQEVA
                     ITQILSGIEQISIVVQMNSATAEESAAASEEMSAQAQILKELVEKFHLKESEVRESSW
                     V"
     gene            complement(14393..15352)
                     /locus_tag="JAM15_08105"
     CDS             complement(14393..15352)
                     /locus_tag="JAM15_08105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HAT6798211.1"
                     /translation="MKNKQQGTILVVDDSVLMCDLIDKTLTKDNFKVKKAFNAIEAKE
                     FIEEFIPDIILLDIILPDNSGFEFCKEVKSNARTADIPIIFITSKNTDTDIVKGFGVG
                     AIDYMVKPFSMTELKARVIAHLEVKKSQDKLKKINNELESSLEKLNRLVVRDYLTGLY
                     NRRHIINQLMEQRRINKYSETSISLILGDIDDFKVINDTYGHEAGDFVLTVISSIIKK
                     NCRQIDTVSRWGGEEFLIMLTNTPIEGAKILSERIRKEIKEFDFNYKEHKIKCTITLG
                     VVEVNSNISLEENISLADKAMYEGKNLGKDCSVVSTMKGLKKI"
     gene            complement(15488..16006)
                     /locus_tag="JAM15_08110"
     CDS             complement(15488..16006)
                     /locus_tag="JAM15_08110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-binding chemotaxis protein CheW"
                     /protein_id="HAT6798212.1"
                     /translation="MRFPDDPYLDYGLIDEGIKYLKFKVDEQDFGVELEKVIEITGNQ
                     EIIFIPELPTYSKGIINLRGKIIPIIDMRLRLKKDELMTINCMYIVVTEIKDLVVGFV
                     VDRVDDIVSLEKSKILPPPRVTIEYSDYFVSGVGELEGKIITLLDLEKLLTDKDEVLI
                     DELINGFDCTIM"
     gene            complement(16049..16534)
                     /locus_tag="JAM15_08115"
     CDS             complement(16049..16534)
                     /locus_tag="JAM15_08115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheD"
                     /protein_id="HAT6798213.1"
                     /translation="MNREIVVNIADMKIAYRPNVLVTYALGSCVGVCLIDKVAGIGGM
                     LHVMLPYSKDAINIENKCKFADTGINELIKSMENIGANRIYIKAKIAGGAQMFLGSSN
                     SVIASIGHRNVEAVKKTLLGLNIPILAEDTGMNYGRTIRFYTETGELLVDSINKGKKK
                     L"
     gene            complement(16531..17148)
                     /locus_tag="JAM15_08120"
     CDS             complement(16531..17148)
                     /locus_tag="JAM15_08120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheC"
                     /protein_id="HAT6798214.1"
                     /translation="MINYLELDDVHIDALREIGNIGSGNAITALASMINSNVKVLIPM
                     VKILEYNEATSLLGGPENKVVCILLDMKGDINGMFMFLLDESITQLMLSSLFNKEEAF
                     LDEIEAIEISAIKEIGNIMASSYVNAIASMLNMTISVSIPDICIDMVGAVLNVPMIRF
                     SDVGDKVLFIENKFKMSDNYFTSHILMIPEMSSLREILVRLGLEV"
     gene            complement(17214..17576)
                     /locus_tag="JAM15_08125"
     CDS             complement(17214..17576)
                     /locus_tag="JAM15_08125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAT6798215.1"
                     /translation="MENKILIVDDAIFMRMIIKEALSKSGYNNLIEANDGEEACNIFK
                     YEKPDLMLLDITMPKKDGLEVLREIKKLDSSAKVVMCSAIGQENMIVEAIKLGALDFI
                     VKPFKTETLVKVVNNVLK"
     gene            complement(18319..18816)
                     /locus_tag="JAM15_08130"
     CDS             complement(18319..18816)
                     /locus_tag="JAM15_08130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAT6798216.1"
                     /translation="MNYEIVEINEKIVIGISKETTNKDGQAVNDIGELWKKFMGKGIY
                     NAIKGKKNDKTIGLYTDYQGDFTSPYSFVACCEVSSNSDKEKNLEELNTNNTVGESII
                     SKVIPAGKYAKFVIVGGQKEVGDFWFKFWQMDFDRTYISDFEEYQCNTFDTKKQEIHI
                     YIGIK"
     gene            complement(18991..19902)
                     /locus_tag="JAM15_08135"
     CDS             complement(18991..19902)
                     /locus_tag="JAM15_08135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HAT6798217.1"
                     /translation="MKINRLTEIIVILLNKKLVTAKELADRFEVSTRTIYRDIETLSM
                     SGVPVYMTKGKGGGISLIEEYSIDKAILSKKDKESLIVALKTLQATKYPEINSVVNKI
                     GSIFGEQNFSNWIEIDFTEWGSNFNEDDKFTKIKEAILRRNTINFNYVNSLSSQTNRT
                     VEPLKLMYKSKTWYLYGFCKLKDDFRIFRISRIRNLSIKDEVFSRKIIEEVCLNDSKV
                     IKENTITLKLRFKEKMLFRVFDDFNKDLITKNEDDTYDVITEFPIGEWIYGYILSFGD
                     NVEVLEPKDVRDNVITRLRELSKIYSL"
     gene            20704..21555
                     /locus_tag="JAM15_08140"
     CDS             20704..21555
                     /locus_tag="JAM15_08140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HAT6798218.1"
                     /translation="MEINKKHFIQVFLTCLILVVICEFIGQRTIAIGKASIVLFPMLY
                     AVIIGLIITPDLLGKKIKALKKVVGEKEINIAGEVVGIALVMLGIKYGTTVGPNIDKI
                     IQAGPAFIAQEFGHILAPIVALPLALMFGMKREAVGATASISREPSLGVISEKYGINS
                     PEGSGVLGTYLMGTVLGTIYFSVLGSISIYSGLHPYALGMACGVGSGSMMTAAAGSLS
                     TMVPPEMADTILAYAATSNMMSSITGIIFLVFVSLPFTNFMYKILEPKFSRNKKTKEI
                     KSTEGEC"
     gene            21559..22029
                     /locus_tag="JAM15_08145"
     CDS             21559..22029
                     /locus_tag="JAM15_08145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798219.1"
                     /translation="MFANLNLKKSSYQLLVMSVIGVIILIGQRISVGTSIVTALPGMV
                     MLILAAMAAMIIKDLFPKSIFPAFGFATIIGLLLSMPYSPTSEVFLTNTNNINFMAIT
                     TPLLAFAGISVGNKIEALKEMSWKIVIISLIVFTTIFFACASIAHIVLSIQGKI"
     gene            22042..23352
                     /locus_tag="JAM15_08150"
     CDS             22042..23352
                     /locus_tag="JAM15_08150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005982059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HAT6798220.1"
                     /translation="MNKEQLKSLVIKTIDENREKILKIGQGIYKNPEYGYKEFKTTEA
                     VSNFFEQELNLSVEKNIAVTGCKADVNSSKKGPHISILGELDGISCKEHKDANEIGAS
                     HTCGHNIQIAGMLGAAVGLVKSGVLEHLDGKVSFMATPAEEFIELEYREQLKKEGKIT
                     YFGGKQELIKRGYFDDIDISMMFHASDLGEDKALVGPESNGFVGKKVKFIGKESHAGS
                     APHDGINALNAAMLAINNVNALRETFKESERVRFHPIITKGGDIVNVVPADVHMESYV
                     RARTINGMIDANERINKALMAGGMAVGADVEITEIPGYLPILRYKSLDNLFKNNLEDL
                     GLKGKVIDGGDFTGSFDFGDVSHIMPTLHPMIGGVKGALHTRDFEIVDEDLAYIIPAK
                     AMALTVVDLLFDNAKDAKDILDTFTPVMTKEEYLTFLEKHDKTL"
     gene            23564..24310
                     /locus_tag="JAM15_08155"
     CDS             23564..24310
                     /locus_tag="JAM15_08155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAT6798221.1"
                     /translation="MFNAGNRIINTWLYPIQDGFVLIDTGYENGFKHFKKRISKFNIK
                     IKDIRYIFLTHAHDDHVGFLNQILDESPNTKIVMHDKALEILYKGQNSFIGGCNSRTA
                     FLFCQIMKLFGKGEHSFSPLKQEFEKRCILVSDKNRKEIEKELNGKIIDTPGHTADSI
                     SLLIDDGVLFCGDSAMNGFPSTHKITIFAESKLEFIQSWKTIINTKPKMIYPGHGKPF
                     EYSKLEQNLIYVNKINLYPLHNSKDIHRFL"
     gene            24672..26213
                     /locus_tag="JAM15_08160"
     CDS             24672..26213
                     /locus_tag="JAM15_08160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HAT6798222.1"
                     /translation="MNDNVVKKKNFFDRTLNRIETVGNKLPDPVTIFLGLCVLLLILS
                     SLVGSMGISVVHPGTGETITAVNLLTVEQLQILLGNIVSNFQGFAPLGLVLVTMIGAG
                     VCDKTGLMTATIKASVSKIPETRVTLVVMTIGMLANIASDAGTILFPPLAALVYLGVG
                     RHPLIGLFSGYAAVCLGFAANIMISVNDILAASFTVPAAQMIDSGFQANATMNLFFMI
                     ASTFVLILLATWVTEKIVAPRFGKYEGNAELDVDGSLSDVEKKGLKKAGISILIYVAI
                     IVALSVIGKKPFLADPETGDLLSNNAPLMKGMVPIIALAFFIPGVVYGKTIGKIKKDK
                     DVVSIMASAMSDMGGYIILAFAASQFLQLFTNSNLGLILAVKGGEFLKSAGINGPLLL
                     IGFIILSCFINLFIGSASAKWAILAPIFVPMFMMVGYNPALTQMAYRIGDCITNPLSP
                     LFPYFPIILAFTRKYDKDAGMGTVIANMIPYSISFLIVWTILLILFMVFNIPLGPGIL
                     PSYSM"
     gene            26248..27354
                     /locus_tag="JAM15_08165"
     CDS             26248..27354
                     /locus_tag="JAM15_08165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HAT6798223.1"
                     /translation="MLDKNRLINNFMDMVRIDSPSNQELEMSKWLVNYLKERNIDAII
                     DDAGEKYGGNTGNVIAYIKGEEGSRPLCLCAHMDQVQPCLGVKPILDGNVVRSDGTTT
                     LGADDKAGIAAILEALEHVTTEKIPHRDIYLCFTICEEAGMHGVKNFNPDNLPCKDMV
                     ILDSGGAIGSIAYKAPAQQSIKISFHGKKAHAGIEPEKGLNAILVASHAISNMHIGRI
                     DSLTTSNIGKIEGGGATNIVTDKVTLTAEIRSHIPETLEYELNHMEKCCKDAASKFNT
                     TYTFEHSMSYPSFELSRDSHVFKLSEEAIRQVGVVPNPMVIGGGSDANILANLGYNCA
                     ILSLGMYDVHTVNEYVNIDELYDTAKIVYHMIKL"
     gene            complement(27776..29062)
                     /locus_tag="JAM15_08170"
     CDS             complement(27776..29062)
                     /locus_tag="JAM15_08170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAT6798224.1"
                     /translation="MIVGIIGPSDSGFKIKDDLKQIDSDLKTKIYVREKVVDTIEVIS
                     KCEDECDAIIFTGCAVYEFIKSKYEISKPHSFVPRSGTSIMKAFWAIKSANIKLDKFS
                     IDVVDRYVVEDALKEFDIKATSVFCNPFSLEVGESELVEWHIKLFEENKTDIMLTGFG
                     AVYNELKERGYPVFRLQATIQLIKESYDKVKSEYALSKARFSQIAVEILSLIDYKEKI
                     DNYYSDMIKKSDMDKLVVNYVRSIQGSLFLLGRNDYVVFVHKGVADNEYNYDKLFNLK
                     REIKDMGFSLSIGIGTGVTAYQAENNAHKALRHSIDSKEIGIYLVDEDENIRGPLASE
                     NELNYSLMLSDEKVIEISKKTGMSCESVAKIIAISENRKSKIYDSKELAEYLNVSERS
                     ARRILNKIVNAGLGRICAKETSIGGGRPKNITEILF"
     gene            complement(29185..32283)
                     /locus_tag="JAM15_08175"
     CDS             complement(29185..32283)
                     /locus_tag="JAM15_08175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HAT6798225.1"
                     /translation="MDVINLIDELDEIVYVSSLDTYELLYINEIGKKAMGINDISHVK
                     CYKALQGKDSPCEFCTNSILKEDEYYIWENTNTRTNRHFILKDKLIKWEGKHARLEIA
                     LDITEKEDISKSIAEKLEIKELLVGCIKHLITESNFSDAVNLVLTNIGKFHKADRAYV
                     FEVSEDRKKVTNTYEWCNEGVDEQKQALTNLDINELKNWFLLFEQKGFVIIDDIENIK
                     EEQPIEYEILKPQKIESLMTSSLKQDDKVVGFIGVDNPHKAVGDTSLLTSLSYFLLTE
                     MKKRKVENKLNYMSYYDFLTGAYNRNKYIKYIDNFQKGKVKSIGVVFVDINGLKDIND
                     NFGHANGDSAIVSACVIIKKYFHSYNVYRIGGDEFVVLCEDISKQLFEELVSWLSEEF
                     KDEMIYSVAVGSIWSDDNIDIHKLIKVADERMYQDKKRYYNKNKLRNNEMEVISDLAD
                     STNNILFKHKELVDKVYFDDLMIKGYSKAYEKLAYNTYDIILSICIDTNLITPIYQSE
                     SNIFSFPIKENLEKTFSYIKKHLIHPDDIILFDDNHLLKSLDSLNNSKQDDLELNFEY
                     RRLGIDKKYYWALIYMLKISSKNKLGEKQTHILVAIKNIDYLMQLHKNQKDILTGLYN
                     YESFCEQTSLMLKRYPDKSYAIIMMDIDKFKVINDIYGVRGGDKALIYVAELIQKNIG
                     SNGICCRMYADVFCIFYESYSDKDVHKLIYKIKNSLNRKKFEYMLVPCFGVYKILDNN
                     IPITNACEMAGYAHKKVKKQSINNYIFYDDTIRNDALEEKQMEREMEYALENGQFHVY
                     LQPKYNLNANKIVGAEALVRWVHPEKGIIPPIKFISLFEKNGFIIRLDMYVWEQVCSL
                     IRKWIDLGEEPVPISVNVSRLHLHNPHFKEIVLSLINKYSIPKSFLELELTESLFIKN
                     IKLFTKIIADLRMDGIVLNMDDFGSAYSSLNMLKNINIDTLKIDCGFFNEEGITDREK
                     IVLRHTIAMAKDLDMDVVAEGVETKEQAEFLVSLDCVVIQGYYYCKPIPSADFEKLLY
                     QK"
     gene            complement(33432..34136)
                     /locus_tag="JAM15_08180"
     CDS             complement(33432..34136)
                     /locus_tag="JAM15_08180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6798226.1"
                     /translation="MEIKPLVLIVEDDKPICKFIKVSLETQNYRCVETDNGGTAISLI
                     HSLDPDLIILDLGLPDIDGIEVIGRVRACAKTNKIIVVSAREHERDKVEALDGGADDY
                     LTKPFSVTELLARVRVALRNKAQQDNINNDAPKSFEVKNLKIDYENHIVSINGEEIHL
                     TPIEYKIIELMSKYSGRVLTHKFIIDKVWGNYYESENQSLRVFMASIRRKIEKNPAQP
                     EYILTEVGVGYRMADE"
     gene            complement(34127..35734)
                     /locus_tag="JAM15_08185"
     CDS             complement(34127..35734)
                     /locus_tag="JAM15_08185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4118 domain-containing protein"
                     /protein_id="HAT6798227.1"
                     /translation="MKKERLQHEDLKEYDYDEDGYLSKKIIIKDFIKTILVMTIATGI
                     SVVFEKVGFNESNIILVYILGVLFATSITYGYFFGILSSVIGVLSFNFFFTHPLYTFL
                     AYRKDYPMTFCIMLMAAIITSTLTSRIKREVRLSHKREKMIRLLYENNKTLLKAKNKN
                     QIIEFCGSNLVNILNRTVIVTIADENNNLGKPSIYICNNDGSENIFHSVLEKEAIKEA
                     FRTGNPVGIGTKYCKNSSAYYFPIKGQESNVLGVIGVACFKIDIITENEKILLEAVST
                     QVALAIDRENLFEKNKKANLEAERERLRGNLLRSISHDLRTPLTSILGSSSTILENDD
                     VIDKETRVELLKNIYEDTSWLTHSVENILSMTRIDEGKLDIEKRPEVVDEIIAESILR
                     VKKFANSRDIKTNIPDEIIIVHVDVLLIEQVLVNLIDNAIRHTPKNSKIELTVKKESN
                     QVLFEVADNGKGIPNEDIGNIFNRFYTKNKSRNLERRGIGLGLEICKSIVEAHGGEIV
                     AFNNPSGGATFRFSIPMYDEEGKDKWK"
     gene            complement(35988..37166)
                     /locus_tag="JAM15_08190"
     CDS             complement(35988..37166)
                     /locus_tag="JAM15_08190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798228.1"
                     /translation="MEKLSDKRRVKAVSMETFVFIVLLAVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLDTVFLIMAMAVLAGALSALLSEFGVISLVNKIFKGLMRPIWGLPGASIA
                     GVVATYLSDNPAIIPFAKDKTFTQYFKKYQVPALCNLGTAFGMGLIVTTFMIAQGKEY
                     VLPAIIGNVGAIIGSIISVRIMLTFTKKYYNYDPKNDTEKQINDKGAKLEEFREIRDG
                     NVFQRTLDAILEGGKLGVEMGMAIIPGVLVVCTLVMLLTFGPSTDPATGQAVYTGAAY
                     EGIKLLPAIGDKISFIIEPLFGFTSPEAIAFPVTALGAVGAAISLVPEFIKSGAITPN
                     DIAVFTAMGMCWSGYLSTHIGMMDALDARPLAGKAILSHTIGGLCAGICAHFIFMLVG
                     "
     gene            complement(37392..37886)
                     /locus_tag="JAM15_08195"
     CDS             complement(37392..37886)
                     /locus_tag="JAM15_08195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter"
                     /protein_id="HAT6798229.1"
                     /translation="MHLFIEVIAAFFTALSFGVLFNMKGKNLILAGIGGSIAWFSYKF
                     LLNMGVTENLCFFIATVCFAIYCELCARIYMTPATTLSVCCLIILVPGYGIYNTMYSV
                     LTNNYIKAVEYGVSTLSCASSIALGLVFITTVFRKVNLYGVLTKIKENEKYKKSINKI
                     KQQK"
     gene            complement(37887..38648)
                     /locus_tag="JAM15_08200"
     CDS             complement(37887..38648)
                     /locus_tag="JAM15_08200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HAT6798230.1"
                     /translation="MDIDRILNFSSNAGKAMLQSGGETYRVEETIARICQSFGIDHVD
                     VFATPTAVMASVFVDGKLHSAIKRISSRRVDLNLVHEVNSLSRAISINNLDIELCEKI
                     LDEISEDNYYSDLITIFFAGIAAATFSILFGGNVEEFIAAFTVGILTKFVIMYLSKSS
                     LNDFFVNAIGAVIIASCSILILKLGFIKTLDHLIAGAIMLLVPGLALTNALRDLLDGQ
                     LISGLAKLAEVFFVGVSIAVGMFLVLGLYFKLGGI"
     gene            39371..42205
                     /locus_tag="JAM15_08205"
     CDS             39371..42205
                     /locus_tag="JAM15_08205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAT6798231.1"
                     /translation="MLRKDKVLLSLHKLCENMTLKDLQSDKTGFTTIEIANHSSLDRS
                     NTSKELNNLYNEKKVLKISGKPILFLHASIIENLIGRTLNSDEFSINNCNELLKSSKN
                     DSEDIFSTLLGHDSSLKLPIEKAKSAILYPPKGLNTLLIGPTGVGKSTFAETMYKYAV
                     ESKIFSSESKFVVFNCAEYAENANLLLSNLFGYVKGSFTGANKDKFGIVAQADGGILF
                     LDEIHRLPPEGQEMLFLLMDKGIYRRLGESDIVHKANVFIVCATTEDIHSSLLGTFLR
                     RIPVTINLPALQDRSLKERLSLIKYFFIIESKYTNATIKVHKDVIKSLLLYDCFGNIG
                     QLKSDIQLMSARAFLNYKTGLKDNIEIDLSLVPDYIYIGLLKLNENRSNLNKLSELDY
                     MLFYEFNGNNLEVEYTKELSKYNIDTSNNGFKYSTEIPYLENDIRSMFINYMEKYSTK
                     LLSISSVTHSDYTSNEIFKVINPKIYYAVEHSLKEAEKISRNKYTKQTYIALSMHISA
                     LIENINQDTYNPKYNLYNDKIFLDKDLNIAKIVLSIIENDLQTSLPKDEVKFISMFLN
                     SMYLEPNNQSESIGVIILAHGNSTASSMCDVANSLLGTNHCNAIDMPLDVKVSTILDK
                     TIELVKECDEGKGVLLLTDMGSLIAFGELISEKTKIKTRSIEMVSTPIVLEAVRKSTL
                     PEMTLDELANSLSSLNPYIGRAAIDSTEINYPEKSREYVIITTCITGYGSAMKVADFI
                     NSSLKNISKYNINLVPHNIESFKMYKNKFSNTKILAVVGSVDFNVANTPFIHIEELLN
                     GYGLDMLNKIIEGTFNANSITNIKETNLSYNSLIINFMTQNLELLDSVKLFNYVNSSL
                     FTIIELIDENLKSKFKLGYILHCSFMIERCFKNTTFPYNNITELISKNHELYSLIREA
                     FKPTEAYFNILIPDEEIAYIIDMINEYLNK"
     gene            42248..43492
                     /locus_tag="JAM15_08210"
     CDS             42248..43492
                     /locus_tag="JAM15_08210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HAT6798232.1"
                     /translation="MEDEILKGKIKQLTILTLIFIFITPVFAFADTPPVPNSSRAALL
                     IDQETKRILFEKNIDEKMPLASLSKMMTFLLAIEAVDKNQVKETDMVKIDKSTASVGG
                     STCKLKDGDEISLGELMQGLMLVSGNDAAIAIAKHIGKTEKNFVNMMNKKAEEIGMID
                     TYYFNPNGLPIYTDPEHKEPPIENMSTAHDIVTLGKYMYDHYENQVTRITTMQVYNDT
                     KKDFTHYNTNPLLVSVPGVDGIKTGYTDNAGYCLAFSMMVPKDAKNERNHRLIGVVLG
                     DGNKKNRISSSATLLKYGKDNFHSKKIAHKGDIIETPCVDGIDDFKITVKVDKDLYGV
                     VSDSENINPKVVFKNMNYPIHKGDIVGVAKYYNDSGKFVGSVDVKSESNIGCIPLKDK
                     IKIKVAKINKKLEIKNSVCFKV"
     gene            complement(43933..>44109)
                     /locus_tag="JAM15_08215"
     CDS             complement(43933..>44109)
                     /locus_tag="JAM15_08215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798233.1"
                     /translation="TYKTAIDEAQAILDKADATQKEIDDAVTALNTATATFEAGKVPT
                     TIALMLSRILGFMK"
BASE COUNT        14871 a         7367 c         4990 g        16881 t
ORIGIN      
        1 tttaaataat actattatct tcatcagtga acctaaactg caactttaga cttattagct
       61 aaagccaata ttagacctaa agctatagat gcaaatgcag aagcaattac tctatactca
      121 gcagggaata agaatacaat tgtatgacat ggtatccaga aaaatggtat agtttttaaa
      181 acactaaaac caaggtaagc attccaatcc acaatattta ccacatcttt aagttttacc
      241 ttaatcccct ttccaacctc atatttttta tctataaaac agtccataac cttatggaat
      301 aaaaatacag ttggtgacat tagtatattc atagttgcac tcttaaatag agcatttgca
      361 aaagctattc cctcaaatgg aagcatacca tccacttgtg cttgacctac acctgatgag
      421 tagattgaca ttccatatgt ggtaactaca cctattattc cccaaactat tgctctataa
      481 aatactccta ctggtatttt ccaatcctta tacaaaattc tagcaccaag taaatctccc
      541 attgtagcta atacagcaaa ctttaaaaaa cccccaatat atggatgtgc acctgttgct
      601 tccataaata cttctctact acttggtatt gctaagacag caataataca aataagaact
      661 ccactccata taaaatcgcc ttttttcata tttataaata ctatttaata tataaatagt
      721 tctcctttct attaaagatt tatttaattt acaatctatc tacaattatt tattaatcac
      781 ttattattag atattcattt tccatattta aatttattct atccctttat ctatttattt
      841 tcttactact ctatccacca ttatctatat atttatttta cgattactct ttcaccctaa
      901 ccctttaatt atctattttt ttcttactat tcttatctac catcatccat atatttattt
      961 tacgattact ctttcaccct aaccctttaa ctatctattt ttttctgata ttcttatcca
     1021 ccatcatcca tatatttatt ttacgattac tctttcactc taacccttta attatctatt
     1081 ttttctgata ttcttatcta ccattatcta tatatttatt ttacgattac tctttcaccc
     1141 taacccttta attatctatt ttttctgata ttcttatcta ccattatcta tatatttatt
     1201 ttacgattac tctttcaccc taacccttta actatctatt tttttctggt attcttatct
     1261 actattatcc gtatatttat tttatgatta ctcttttaac ctacccccta tactttatag
     1321 taatatgttt ttaacctttt tcattattcc caatatgctt tataactaca aatactctcc
     1381 ccccttaaaa ataataataa aattaatcaa taaatttata atcatattat tactctatgt
     1441 attaagcaat tactatgcca ataaattttg atttttttaa acaaatctta aaaatcctaa
     1501 aatgctaatt ttctttaact tttaatgaat ctaatagata atatttaatt ttcgttatat
     1561 ttttcagaat gtttcaatta ttatttttaa gaaaaaaaaa taatgttaac atttcttaac
     1621 atacattaaa aaatgttaac attataaatt tggtttaata cttttacttt gactcgattt
     1681 acttttattc tacttcttac tttattttta acttagactt tattttttta ttacttattt
     1741 gagtcttatt tattttattc tcactccata tgttcaatta catttgtcta aattctttga
     1801 tacttttatt acataatttt aacaagctta agtgttattt gggtagtgca gttgataatt
     1861 atttaaataa tcatcaactg catgtttata tcattacagt agcttaatgt atttaatcat
     1921 acttacttag gattttgaaa tatcttagag attatattta acattagtca attgctgcat
     1981 aattgtaagc aattgaaatt tgagacccat cttcattttc tatagtgata ggcttcataa
     2041 tttttaatcc ttcagttttt atcttttcta attcttgttc cattttctta attgtttcct
     2101 caaggtcttt ttgacttaca tctttgactg cattagggtc tttagcatag tcttttaatt
     2161 cttgaatatg tttagcatac tcttcataag tataatgctc aacaccatac ttttccaatt
     2221 cagtagggtc agttattcct gattttatta gagattcaag tttaggtaaa gcaatattag
     2281 atgaatcatt tccatttgca aatactgctc cagttcctcc tagtaccatt gcagatacca
     2341 tcattgcact tataagggat ttttttattt tcataaccaa tcttcctttc ttagagattt
     2401 atttgggtag tgtagtttaa aatgactatt gcaatagtta tcaaccacat ctttagacta
     2461 ccatagtagt catatttgtg tcaagtcttt ttaaaaaact tttcaataaa aaatactatc
     2521 tcaaaacaaa attaattatt ttgagatagt attttaattc taaatctttt atattactaa
     2581 gatttatggt tactctatcc atgttctata ttgttcttta ttaactgcta acaaattccc
     2641 ttttcttgat atgacaaagc gattatcatt atagttactt tgctcaattg aaacttctcc
     2701 tgaatcagta taaagtatat ccttactatt actagattta tttacatacg tttcttcact
     2761 attctcagaa ttagttactt tgctcataga tgattcttca tgctctctaa attcaattac
     2821 agatactttt gccgtactaa aatgagtctc tccatcactt ttagctttac taacaagaat
     2881 atcagattct actttgggag aatataaatc agttgattta ctacttattg aaaatccact
     2941 tttatcactt tgttcatttt ttgttaagcc aaaagattca acctcattaa tctctttatt
     3001 ttctgttgca aaaacaagac ctgtcccaca aactaataca gttgaaacta aaaaagtaac
     3061 ataagttgat tttttaaatt tcataatatt aactattctc ttttctattt ttgtctttcc
     3121 aaatccacta catattgtca ttgaaaatgg attattctcc tctgctagag ttattagtgt
     3181 ggttgcataa tcagccctat attcttcacc aagtatactc ataacctttt catcacaact
     3241 aaattctatg tctttattta gtaaaaaaaa catcacccaa actaagggat taaaccaatg
     3301 ggcaacaaga gctacaagca taaataactt taacagatta tcaaagctat taatatgaac
     3361 catttcatga gttaaaacaa agtctaaagt ttgattatta gcataattca tttgctttgg
     3421 caagataatt cgtggtttta aaataccaga tgtaagtggt gtcctagtaa attcagatat
     3481 gcaaacaata aatcttctaa aacggctatt cttacacatc cattttttaa tgaactcatg
     3541 attttttata tgaattgaag ttttaaaaag attaattatt ttaaaatatc taaagcataa
     3601 aagtatgcta aacataatag taactataaa agacaaaatg cccaacattt ccaacatcat
     3661 aatattttca atattagaca ttatttcaaa ttcgtcagaa ttgtttttac ctgtagagtc
     3721 actagctttc ttaagagtat aattttctgt tgatgtatta cccaattcta catcaaaagt
     3781 cgattcaatt atactataaa tactaaaacc agaatttaaa cttactggta ttagaagttt
     3841 aaataaaaca atcaaccaca ataatacaaa taccttttta ggtaattttt taaataaaca
     3901 tgctcttata aaaataacta ttaaaagtaa tactccagaa gtaaaactca tttctaacaa
     3961 tttaatgaac ataaatctta cctcacttta atttttcaac aatttgttta agttttgtaa
     4021 tctcatcact tgaaagattt tctttattaa taaaagctga aagaaatttt tctgaagacc
     4081 ctccaaacat tttattaatt aaagtttctg tttcctgttt ttgtacttcc tctttgctta
     4141 ttaaagcttt acaaacaaaa tttggctcaa ttctctctat tgcacctttt gacactaatt
     4201 tttttataac ggtatacgta gtgtttctat tccatcctgt ttcttctttt aaaattttta
     4261 ctaactctcc agccttgctt tctcctctct cccatagaac ttccattact ttaagttctg
     4321 aatcaaataa ttttatctcc atataaaatc gctcctcaaa tatagttatc acaatagtca
     4381 ttactataat aaaaaactat catagtagtc tatactatgt caatcattta ttttttaata
     4441 ataaaaactg tctttttaaa aaattcttat aaaagacagt tttatcaatg ttatacttta
     4501 atgtttaatt aaagccatat tttatttaaa tatataacta tctatcttag tacatagtat
     4561 aagatttttc tttatctaat agtatatcct ctacatctgg gttttctttt actaattgtc
     4621 tataaaaatt acaattagta acacctacat atggaattag ccatagtaga cctattccaa
     4681 gagtagctat tgaaagtata taccatccta taaaactaaa gtttagtaca aataatttaa
     4741 gtacatttcc tttcatcata tctaaactag cacccattga tttaaataca cccatattat
     4801 ccttgtcttc acaaattaag aaagtagctt gagaaacata taatagcaat atataaactg
     4861 gtaacataag aacaagtatt ataagaacta gagttattcc agtagaaata atagtcccta
     4921 ttccaacatt atcacttgat aaatattcaa ttgctccact agtaagtaaa actccaaatg
     4981 ataaaaacgc tcctataatt gtgattataa aagaataaat ataaacaata attgattcaa
     5041 ataaataaaa accaaaactt cttaaataaa ttctcccact tacaaagata tctcctatct
     5101 tgactttttc atctttagta attttcaaga acatacatgt aaatcctgct gaaacgcaaa
     5161 aagctattac agccactaca atagtagtca atggttcaaa aggtaatcct acaattgata
     5221 ttaatactat caatgcaata tatactgcca tagaaattgc acatattccc cagtttccag
     5281 ataactgagc tttagatact cgttttaatt cttgccttga taccataaaa aacacccctt
     5341 tcattttata aaaaaacttt taaaaatata aataatcttt taacgtataa tattaatata
     5401 tcatattttc gactatataa gatacaatta ttcaccatgt tttatcaaga tatgccataa
     5461 ttgtattact agttttatat agtcaacatt accaaataca tcaaataaat ttgattaatt
     5521 attcaacaag taataaaata atttctatta attgtacttt atttagtaaa caaattattt
     5581 aataaaaaaa ttacttaata cagtaaatta attggtaaga taaattattt attattagta
     5641 aagtaaatta tttactattt atcaagataa attatttata aaataaatca tttataaaat
     5701 ataatttata ctttgaaaat aaaataaact atcttccaaa cattttatta tatgcttaaa
     5761 agatagtttt gtgtctttaa aataaattaa attgtatata ttccttcaca taacttttgt
     5821 atattactag gtggttgcca tttaccatct tttttagtat atgtaatcat agttgtaact
     5881 tccttagttg gtttcttatt gtaaaggtct ataatcattt ttgtcatatc atcttgaact
     5941 tctttttctt ttttatcgta attcttttca tcagttacat aagattttac taaagtgttc
     6001 gcttcactca ttactttact agtatctaaa gctttactta caactttcaa agttatctta
     6061 tccttactag aagattccac tgttactgtc ttttcaacac cttgaattaa tttaacaatt
     6121 gtttcgtata tcttttcagc attttcttta ccataaagag gtgtcaattg agcaatcatt
     6181 gaaaccttgt ccttgctgtt ataagtttga atctgtttat attcagcttc tgttaatgca
     6241 tcagaaattc ctttttcatc atacttatac atttctaatg cagctaaatt agcttcaaaa
     6301 ttcgacttta ctttttcttc tgcattagaa caccctatag ttagaactaa aactagagcc
     6361 ataatcgtag acaatattaa cttttttacc attttcatac aaacatcctc cctcaattaa
     6421 aataataaaa aatttattta tcaacattat aacataaatt tgtctaacta tagaattatt
     6481 ttgaatattt taccacttcc agtctattcc aataccgttt tcttttgctt tatcgtatat
     6541 tctttttgct gttacgacat cttgtacacc tatcccaaca gttttaaata caattatctc
     6601 atcatcatct tctcttccag gaatagttcc atttataacg tttcctaaat caccactaaa
     6661 atcatcttta cttatcttac cttcttttaa tggaattaat atatctcctg actcagataa
     6721 aactgcatct gttgattcaa aaaatatctt agacgctcta gttaaacagt ttgggcacaa
     6781 ctcttgcata tctggcatat atgaacctac tgcacttatt aaagctcctt ttttcactaa
     6841 gtttccatta agtactggtt gttttgatgg agtagctaaa actatcacat ctgcgttatc
     6901 tatggcttca tcagatgatt caactgcaac tattttagta ttatatttac ttaattttaa
     6961 gttcatttct tctgcaaatt tttctctact ttccctgttt ctactaaaaa ctcttacctc
     7021 atccaaattt ctagcttcta tcatggcttc aagttgtggc tcaccttgtc ctcctagacc
     7081 tatcaaagct ccaatcttag aatctttttt agccaataca tctatagctg ctccagaggc
     7141 tgctccagta cgaatctgag ttacataagt accatccaat actgcactaa cttctccagt
     7201 ttctccatct aataatagta ctgttgctgg aattactggt ttgccttttt gagcattttt
     7261 aggaaataca gatacaattt ttattccccc acagcctaat tcttctacgt atcctggcat
     7321 aaataacata ctagcatctt gacttggaac agatatattg gttctcaaag gatttacact
     7381 ctttccttca caataaattc taaaagcttc cttatcagct tcaattgcat ctctcattgt
     7441 aaatactttt tttatgtcgt ctttttttaa aagtagcatt tttatacccc caattttaat
     7501 aagtttctat gctaaatatt atagcataac atttaattta atcttctatt tcaaatcaaa
     7561 taaatctaca tactctggtt ttagcataga acttatcaac gctttattta ttgaaaattc
     7621 tggtattccc gctgcatatg gagttatatc atataaatca aaatatacaa ctagattctc
     7681 atcttgcaag taaaagtttt gattctcttt tataccttta aaattatata ttccgatatt
     7741 ttcttcatcc tttttttcaa gttcagctat ttgtctttta atttcttcat ctataacttc
     7801 tttatattta gtattatcct taaataagtc cattaattct aaaaattttc cagttctcat
     7861 atccacatta tatgctatat cttgataaaa tccatgtgct ccaccactat aagtataata
     7921 tctcactttt atactaagag cagaatcagt attcttttta agttcaaagt ctacatttgc
     7981 aacaaactta tttttctcgt caggattatc cttaagatac tgctttgctt ctttatatga
     8041 tttattataa aattcaaata tgtcattttt tatcttatca tttgtagacc tttcaacaat
     8101 tttatttgaa tttgttatta caggcatgtt tatagtactt tctaaatact catcattttt
     8161 cactattgtt ttacttccta ttgtacttac tgataaagtt tgtttactat ttgtattacc
     8221 ctttggtaat gactggttac tcataacagt cactgcttcc ttattactat ttagattaat
     8281 tgaagcatct ttccttaaat tattatattt atagtcatgt ttaattgcca aaacagccat
     8341 tatagtcaat gttaaaacaa atacatatct taaaacttta gcttttgtat cgactttaaa
     8401 aaatttcata ttatcatttt cctcctaaat ataaatctct cttattatat ttggagtttc
     8461 tagggttttt tatccatata atttaataaa agattaattt ttatttataa aaaattaatc
     8521 tttttgtttt aaaatattaa tatgtcttat caaacagttt gaaatttcac caagaggtaa
     8581 ttgtaacata acagaacctc tatcaaaagc taccattggc attccatata ctatacaaga
     8641 attttcatcc tgtccaattg taaatgaacc attttctttc atttttaaaa gtccatttgc
     8701 tccatcataa cccatacctg taagtattat tcctattgaa tttttacctt ctacttctgc
     8761 tactgaatca aacaaaacgt ctactgatgg acagtggcca cttattcttt ctcctttttc
     8821 acaagttaca taatatcctt gtttatccgt acacaatttc atctgataac ccccaggtgc
     8881 aattaacaca tttccttgtt ctactctgtc attattctta gcttctctta cattcataat
     8941 acactgcttg tcaagccgtt gtgcatacat ataagtaaat atagctggca tatgttgaac
     9001 tacaacaatc cctggtgttg attttggtag gtcttttata atttcaagta ttgcttctgt
     9061 accacctaca gatgcgccta tagcaataac catattatta aaacgttcca cattaccgcc
     9121 tccaaaaaat catatatcaa aaataccttt ttatcgttta tatatagcag gttttacata
     9181 tttgtattta gtactacttc tgttgattac ttctgcatgt cctacaaaca aaaaactatc
     9241 ttttttggta gcattataaa atttatttat aagttcttct cttgttttta aatcaaaata
     9301 aatcataaca tttctacaaa aaatcaaatc aaaatgttga tatgagaaat cattcattaa
     9361 attaaacggc ttaaaaatta cactttttct aatcttatca caaattttaa atgtaccatc
     9421 cttgttgtct ataaaatact tcttcttcca taactcagga acattgttaa catttgattc
     9481 tatgtatata cctcttttag ctttttcaag tgagttagtt gaaatatctg tggctatgat
     9541 tttaatgttc cacaactctt tattatatcc aaaataatca tccaaagtca tagctattga
     9601 atacgcttct tctccactag aacatcctgc actccatata tttatgtttc ttattttatt
     9661 attttcttcc caaaaaggaa gtatactatt ctgtataaac tcaaaatgtt gaggttctct
     9721 cataaaaaat gtgtggttag tactcaatct atttattagg tttatagctt catttcctgt
     9781 cttatcttta aataatagat tcatatattg actaaaagaa ctaagttttt tctctatcat
     9841 tgtattgtat aagcgacctt caattaacgc tcttttttta cttaaatcaa taccatattc
     9901 tttttttaca tggtttacaa gaactataaa ttcttcatct gtgagtttta tcatgcaaaa
     9961 acttcctcct gctaatttat cagaactaac tacatgctat taatcaaaaa ctttcgaata
    10021 tctaaaatta atatagaatt atcttcaact ttcgcaatct cttttatatc tttattaata
    10081 ttagtgttgt tagaattagt cgtctctagt aaatttacat tttctatatg aataacatca
    10141 acaactttat ctacaataat tccaacttga tactcatcaa cctttgtaat tattatacaa
    10201 gttctctcat tataatcagc tttaggaaga ttgtacttta tatgcatatt aataactggt
    10261 attattcttc ctctcaaatt aataactcca cttatatatg ttggaagaca tggtacatac
    10321 gttattgatt gaaatcttat ggtttcaatc acattttcta attctattcc ataaataaca
    10381 tcattgacat aaaatgttaa tacttgttta ataatttcat ctttagccat actttaaatc
    10441 ccctaatata tttctataat gctatctgca tctataatta aacttatact tccatcccca
    10501 agtattgtac atcccgataa acccttattt tttatattaa atcggttaaa ataaactgga
    10561 aatggtttca caacaacttg ctgattacct attatttcat caacaaaaat gcatactgct
    10621 ttatgctcat tttcaataat tatcatatta ccatgcatca gattggttac ttttgtttga
    10681 atattatata ttttatgtaa ccttataatg ggaatacatg ctccatatat tgtaattaac
    10741 tctgtcttat ttccttctgt aattatttga tttaagtctg taagtttaaa tgttcttctt
    10801 atggatgata ttggtaaagt aaatagtgaa tctccaactt taaacttcat accctctact
    10861 atagaaagag ttaatggtat ttttatagta aaggttgtcc cttcatcctg tttacttttt
    10921 acttcaattg aacctccaac tttttcaata cttttacgaa caatgtccat gcctactcct
    10981 cttccagaaa attcagttat agattctttt gtagaaaaac ctggagtcat aatcaaagaa
    11041 ttgacctcgt catcagtata ctcattaatt tgatgtttaa gaagaccttg ttccttagct
    11101 tttgccaaaa tcttatctct cataatgcct ctaccatcat ctgaaatact tatcacagct
    11161 tctccgccta gattctcagc agataaaact atctttccca cttcttcttt acctttcgct
    11221 atacgctcct caataggctc tattgcatgg tccatagcat ttcttataag gtgcataaaa
    11281 ggttctgcta aattatcaat tacattctta tctacctctg tctctgctcc tatagttatt
    11341 aactctacat ttttatctaa ttttttattc atatctcgta caattctatg cattttttga
    11401 aatacaccag caatttgaat catacgcata gacattacta tatcttgcaa ttcatctgta
    11461 agcttgtgta attgtcttgt tgccttattg aaattatcta tatcaacacc tgtagaattt
    11521 acgctattta caaccattga ttccataatt acaatttctc caactatatt ttgaagtaaa
    11581 tccaattttt ctaaatttac actcataata ctctgcttac ttattggtaa atgttcattt
    11641 tcttcactta gactatcttt ttccatatca gttttttcat ttaaaacatc ttcttgtatc
    11701 tcatcttctg tatagttatt ttgataactt ttacttactt tattattatc ttttaattta
    11761 ttttctactg catcattatt tgatgtactt ttcatttcta tttctttttt actaatattt
    11821 atgtattctt ttacatagag attatcttct atagttttat aaactattgc cttatcctct
    11881 ttagctacaa attgtatata aaacccataa cttttaatat attctgtaga ctctgcattt
    11941 gtttctacat cttttggata aaaatctata aattcacagt aatctctaag ttcaaataca
    12001 agcatgaaag ctctcacatt ttccatcatg caaccttgtt caaagattat ttttactaca
    12061 tcagagtctt ctttgtattc aaaatttgaa tcgattgctt ctttttcgtc tgtactttct
    12121 aaatttgcat tatcctttga tttcatagaa cttgataatt ccaaagtact cacatactct
    12181 tcaattcctt caataaaatt agagtaatca gaagatatac aacctcttga ttgtaactca
    12241 tctatatctc ttcttataaa atctaatgat tgaaagacta aatcaaataa taggtcattg
    12301 tctaaaactt ctattttacc ttcacgtata gcataaaaca agtcttctac actatgtgct
    12361 aaagcagata tattgtctaa ccccatcata gatgctgaac cttttatcgt atgcattatt
    12421 ctaaaagttt cattaatgtt gttatgagta aatactttct ctttttctat ttgaatcata
    12481 atttcatcta attgttcgag taataaactt gtctcaaata taaacatatc taacatttgt
    12541 ctcatactcg gttcaatata attcacattt atcacctacg acctacaaat aattttatat
    12601 tatatatgca tctcataatt taaatacatg ataattctct tacttcaata ttcacctcat
    12661 aatttaaacc catgatgatt ctcttacttc actttccttt agatgaaatt tttctactaa
    12721 ttcttttaaa atttgagctt gagcagacat ctcttctgag gctgctgcac tttcctctgc
    12781 tgttgctgaa ttcatttgga ctactatgga aatttgctct attccagata aaatctgtgt
    12841 aattgctact tcttgactat gtacagccga agaaatacca ttaatataat tagtagtttt
    12901 ttctacacca tttactacca agtccaatgc atttgcagtc tctttagcaa ttctgacacc
    12961 attttctact gttttaatag cttcttctat gagaatagct gtattttgag ctgcttttgc
    13021 acttttacca gccaaagacc taacttcatc tgctacaact gcaaatcctc taccatattg
    13081 acctgctctt gctgcttcaa cagctgcatt taatgcgaga atattagttt ggaatgctat
    13141 ctcatctatt gttttgatta tttttgatat ttcactcgat ttttcactta tttcacccat
    13201 tgatgtcatc atatcatcca tacatctact tccaaaacca acttgtgatg cagattggtc
    13261 agatacctca catgcaagac tagcactatc tgcacacttc ttaattccat ctgatatctc
    13321 attaatcgtg gaagctaatt cttctactga actagcttgt tcagtagcac cctgtgaaag
    13381 agcttgtgca cctgctgcaa cttgttctga agcacttgca acttgttctg ctgataaatt
    13441 tatttcagaa aaatcaccat taaaagagtt tattatactt tctaaagata ttttaattga
    13501 tttaaaatca cctataaatt cttggtctat ctctactctt aaatctcctt ttgcaatact
    13561 agttaatgta ctgtctataa ggtctatgta atttaaaagc atactttgca tctttttgac
    13621 agaactcact aatagtccta tttcagattt actttcttca acgtctatac ttgttcttaa
    13681 gtccccagat gcaattcttg aaaagtgttt ttctacttta ttaataggaa tcactatttt
    13741 taattttatt actgtatatt ctattattgt caatattatt aaaagggaaa gtataaatat
    13801 tgttcttaat attagacttt gtaattcttt ttttacttct acaattttgg aatttgaacg
    13861 ggtaactata tcctcttgaa attcatttat taaagaatcc attttctctt gagagtttat
    13921 atagtcacta ccaaaaatta tactttgagc tttactctta tcattacttt cgactgcctt
    13981 tattgcactt tgttctgttg gtactaaaga atctgatatt tcttttgctt ctaagatttt
    14041 atttgactcg ctctttgtaa gaccaatttt ttctaatttg tttaaagctg attctcttgt
    14101 ttttccgtat aattcttttt cataaatatc tttattcttt ttttctcctg taaatacata
    14161 tcttcttaat acatcactta tttctctagt tgtatctttt atatactgac tttgagtcct
    14221 caaattattc atatcattaa tacttttttc tactttttca aatgctttat aagatgaaat
    14281 agaagaaaaa atccctgcta gaacagccaa tactataata atcagcaata caattgctaa
    14341 tttagaaagc tttacttctc ttttcatatc tgtactcctt tataaagtaa gtttatatct
    14401 tttttaatcc tttcattgta ctcactacgc tacaatcttt tcctaagttt ttaccctcat
    14461 acattgcttt atctgctaag gatatgtttt cttctaatga tatatttgag tttacttcta
    14521 ctactcctaa tgtaatagtg cactttattt tatgttcttt atagttgaaa tcaaactcct
    14581 ttatctcttt acggattctt tctgaaagta tcttagcacc ttctattgga gtatttgtga
    14641 gcattatcaa aaactcttct ccaccccatc tcgatacagt atcaatttgt ctacaattct
    14701 tttttattat acttgatatt actgttaaca cgaaatcccc tgcttcatgc ccataagtat
    14761 cattgataac cttaaagtca tcaatatcac caaggataag ggatattgat gtttcactat
    14821 atttattaat tcttctttgc tccataagct gattaattat atgtcgccta ttgtaaagac
    14881 ctgtaagata atctcttaca acgagtctat tcaatttttc aagagaagat tccagttcat
    14941 tatttatctt ttttaattta tcttgagatt tctttacttc aagatgagct ataacacgag
    15001 cttttaattc tgtcatacta aaaggtttca ccatatagtc aattgctcct acaccaaatc
    15061 cttttactat gtctgtatct gtattttttg aagttataaa aattataggt atatctgctg
    15121 tacgagcatt agattttact tccttacaaa actcaaaacc agagttatct ggtaaaatta
    15181 tatcaagcaa aataatgtct ggtataaatt cttcaataaa ttcttttgcc tctattgcat
    15241 taaatgcttt tttaacctta aaattatctt ttgtaagtgt tttatctatt aagtcacaca
    15301 tcagaacact atcatcaacg actaaaattg ttccctgttg cttatttttc atatacaaac
    15361 ctctcttaaa cataatatat tcaaatttta atgatttaaa atttttatac ttaataatta
    15421 taccactata ttcttaaatg ttctcatcac aatcttttta taataacact ccaactacat
    15481 ccctatgtta catgatagtg caatcaaacc cattgattaa ttcatctatt aaaacttcat
    15541 ctttatctgt caaaagtttc tctaaatcta gtaaagtaat tattttacct tctaattctc
    15601 caacgccact tacaaaataa tccgaatatt ctatagtaac tcttggtgga ggtaatattt
    15661 tacttttttc taagcttact atatcatcaa ctctatcaac cacaaatcca actaccaagt
    15721 cttttatttc agttactact atatacatgc aatttatagt cattaattca tcttttttaa
    15781 gtctcaaacg catatctatt attggaatga tttttcctct tagatttatt atgcctttag
    15841 aatatgtagg tagttctgga ataaatataa tttcttgatt tccagtaatt tctattacct
    15901 tttcaagttc aaccccaaaa tcttgctcat ctactttaaa ctttagatac ttaattcctt
    15961 catcaattag tccataatct aaatatgggt catctggaaa tctcatttaa tacctccctc
    16021 ctaaaataca ctttctatga aatatatatt ataatttctt cttaccttta tttattgaat
    16081 ctacaagtaa ttcacccgtc tcagtgtaaa aacgtattgt tctaccataa ttcatacctg
    16141 tgtcctcagc taatattgga atatttaatc ctaaaagagt tttttttact gcctcaacat
    16201 tcctatgtcc tatacttgca attactgaat tgctgcttcc taaaaacatc tgagcacctc
    16261 cagcaatttt tgcttttata tatattctat ttgcacctat attctccata gatttaatga
    16321 gctcatttat tcctgtgtca gcaaatttac acttattttc aatgttaata gcatctttac
    16381 tatatggcaa cataacgtgt aacattccac caattccagc tactttatct atcaaacata
    16441 ctcctacaca agagccaagt gcataagtaa ctaaaacatt tggtctatag gctatcttca
    16501 tatctgcaat gttcactact atctctctat tcatacttct aatcccaacc tcacgagtat
    16561 ttctctaagt gagctcattt ctggaatcat caaaatgtgg ctagtaaaat aattatcact
    16621 cattttaaat ttattttcta taaataagac tttgtcacca acatctgaaa atcttatcat
    16681 aggcacattt agaacagctc caaccatatc aatacatata tctggaattg aaacacttat
    16741 agtcatgttt aacatagatg caatagcatt tacatatgaa cttgccataa tatttcctat
    16801 ttccttaatt gctgaaattt caattgcctc aatctcatct aaaaaagctt cttctttatt
    16861 aaaaagagaa cttagcataa gttgagttat tgattcatcc aacaaaaaca taaacattcc
    16921 attgatatca cctttcatat cgagtaaaat acatactact ttgttttctg gaccaccaag
    16981 caaacttgtc gcttcattat attcaagtat cttgaccata ggtattaata cttttacatt
    17041 gctatttatc atggatgcaa gtgcagtaat tgcattccca gagcctatat taccaatttc
    17101 tctaagagca tctatatgaa catcatcaag ttctaaataa tttataatat aaacccctcc
    17161 cttttattat tgcatttatt tgcttttcat tgtatcagtg tatatttaca cttttatttt
    17221 aaaacattat ttacaacttt aactaatgtt tctgttttga agggcttcac tataaaatct
    17281 aacgctccaa gttttatggc ttctacaatc atattctctt gtcctattgc agagcacatt
    17341 acaaccttag cacttgaatc caactttttt atttctctta gcacctctaa accatctttt
    17401 tttggcattg taatatcaag caacatcaaa tcaggctttt catatttaaa tatattacac
    17461 gcttcttctc catcatttgc ttctattaaa ttattatagc cacttttact cagagcttct
    17521 ttaattatca ttctcataaa aatagcatca tctactatca aaattttatt ttccataaaa
    17581 ctaactcctc catatgtaca acaataaacg cttttatctt cagttattgt ctatactatc
    17641 tgactatttt tcgctacaca ataaatacat ttcattgata aataaaagta attatttatg
    17701 ccatattata cttaattctc ttaacataat ttgtcaacaa aaaaacttat atatctattg
    17761 taatatatgt ttggcgtttt gacgagttat taaaaatata attgtataaa acataaaaag
    17821 ttatcaaaag taatcaaatt ataataaaac aactttatac cttttttatg tttgtataaa
    17881 aatttttttc acattcatta aaatcatttc tgtagattca tataggattt gactttctca
    17941 atatctaata gatagttgtt tatttactta attatatttc tctatatgta ttatctatta
    18001 aattagattt agctttatac attatttttt atatttttca aattgtatac tcataaatcc
    18061 agaagtattc taatgtgttt ataatacttt ttttcatatt ttaaattaaa taacaaatca
    18121 ttatatttac aagtatcatt tatcaataaa caatattaaa tgacgaatat gtctgaagat
    18181 tcaaagtgat actgatacta ttaattacta aaaaagcagt aaatctttac agatttactg
    18241 cttatagtta taaataataa aactatctat aataaatgta ctatactcaa tacttcattc
    18301 aatatagtaa taacaaatct actttattcc tatgtaaata tgaatttctt gtttctttgt
    18361 atcaaaagta ttacattgat actcttcaaa atcacttata taagtcctat caaaatccat
    18421 ttgccaaaac ttaaaccaaa aatctcctac ttctttttga cctcctacta taacaaactt
    18481 tgcatactta cctgctggta taactttact aataatactt tctccaacag tattattagt
    18541 gtttaattct tctaaattct tctctttatc agaattacta cttacttcac aacatgcaac
    18601 aaagctatac ggacttgtaa aatccccctg gtaatctgta tatagaccta ttgtcttgtc
    18661 attcttttta ccctttatag cattatatat ccctttgccc ataaattttt tccacaattc
    18721 acctatatca tttaccgctt gtccatcttt atttgtagtc tccttcgata ttcctataac
    18781 tattttctca tttatctcta ctatttcata attcatactt tatacctcac tttgttttta
    18841 ttaatatatt ttattttgaa ctaattcaat tataatttat aatatacgac acctttatgt
    18901 catattttta atataattaa actcagtgag atattatata ctaaatgcaa gatattatat
    18961 atttaataaa atctttaatc tagcattata ttataatgaa taaattttag acaactccct
    19021 tagtctagtt attacattat ccctaacatc tttaggttca agtacttcaa cattgtcacc
    19081 aaacgataaa atatatccat aaatccattc accaatagga aattctgtaa ttacatcata
    19141 tgtatcatct tcatttttag ttattaaatc cttattaaaa tcatcaaata ctctaaaaag
    19201 catcttttct ttaaacctca atttcaacgt tatagtattt tccttaatta ctttagaatc
    19261 attcaaacat acttcttcta ttatctttct tgaaaatact tcatccttta tagataaatt
    19321 ccttatccta ctaattctaa atatcctaaa atcatctttt agtttacaaa atccatacaa
    19381 gtaccaagtc ttactcttat acataagctt cagtggttcg acagttctgt ttgtctggct
    19441 tgacaaacta tttacataat taaaatttat agtattacgt cttaaaatag cttcttttat
    19501 ttttgtaaat ttatcatctt cattaaaatt acttccccat tcagtaaagt ctatttcaat
    19561 ccagtttgaa aaattctgct ctccaaatat tgagccaatt ttatttacta ctgaatttat
    19621 ttctggatac ttagtcgcct gtaatgtttt cagtgcaact attaaactct ctttatcttt
    19681 ttttgacagt atggccttgt ctatagaata ttcttctatt aaagatatcc ctcctccttt
    19741 gcctttcgtc atatatactg gtactcccga catagacaga gtttctatat ctctatatat
    19801 ggttcttgta gaaacttcaa acctatctgc caactcttta gctgttacta attttttatt
    19861 taatagaatt actattattt ctgttaatct atttattttc attcattacc acctactaaa
    19921 attattaaat ttatttaatc taaattaatc atactaattt ttaaataaat aaaatcttag
    19981 aatcttatct aaattattct tacatgattt tatttacttt ctattatctt tctcactttg
    20041 gatattatca tcttaattta tttattacta tatcaattta cttattatca tctcatttgt
    20101 tatcgtctta cttaatttac ttattgctat atcaattcac ttattatcat ttcatttgtt
    20161 atcatcttac ttaatttact tatttctata tcaattcact tattatcatt tcatttgtta
    20221 tcatcttact taatttactt attgctatat caaaaattag tatttgtact taatacttaa
    20281 aattaattta aagtctttac atattattta ttttctattg taatattcat ttccatactt
    20341 tactaagcta cttccactca tttattttaa aatttcaatt tactatttct caactctata
    20401 ttattatttt tcaattttat attactaatt ttaaagcttt ttagctatta ttcctacaat
    20461 atttaaacaa ttttttcata ataaagctat attacaatat attcaaaata tgtaatattt
    20521 tagatatttt tcgttgacaa tgttaaattt ttgttttatc cttaattaag gacatgttat
    20581 tgacatttct gaaacttatt tgaaatagtt ttttcatttt atttaggaaa acgtattata
    20641 cttaagaaaa cgtattttct catttcagat aagtaaaata tttattcttt tggggaggaa
    20701 atcatggaaa ttaataaaaa acattttatt caagtatttt taacttgctt aatcttggta
    20761 gtaatatgtg aatttatagg gcaaagaact atagctattg gaaaagcctc tatagtactg
    20821 ttccctatgc tttatgcagt tataattgga cttataataa caccagattt attaggtaaa
    20881 aaaattaaag cacttaaaaa agtggttgga gaaaaagaaa taaatattgc tggtgaagtt
    20941 gttggaattg cactagtaat gcttggtata aaatatggta ctacagttgg accaaacatt
    21001 gacaaaataa ttcaagctgg accagcattt atcgctcaag aatttggtca tatacttgca
    21061 ccaatcgttg cattacctct tgcattaatg tttggaatga aaagagaagc tgttggagct
    21121 actgcaagta taagtcgtga accttcttta ggagttatat cagaaaaata tgggataaac
    21181 tcaccagaag gtagtggtgt acttggtaca tatttaatgg gaacagttct tggtactata
    21241 tactttagtg tactaggttc aatatctatt tatagtggtc ttcacccata tgctttggga
    21301 atggcctgtg gtgttggtag tggaagtatg atgacagcag ctgctggttc attatctacc
    21361 atggtaccac ctgaaatggc agatacaata cttgcctatg ctgcaacaag caatatgatg
    21421 tctagtataa caggaattat attcttagtt tttgtatcct taccatttac taattttatg
    21481 tataagattt tagaacctaa attttcgaga aataaaaaaa ctaaagaaat taaatctaca
    21541 gaaggagagt gctaataaat gtttgctaat ttaaatttaa agaaaagttc atatcaatta
    21601 ttggttatgt ctgttattgg agttataatt cttataggac aaagaattag cgttggtaca
    21661 tctatagtta cagctcttcc tggtatggtg atgctaatat tagctgctat ggcagctatg
    21721 attataaaag atttatttcc taaatcaatc tttccagctt ttggatttgc aactataatc
    21781 ggccttttac ttagtatgcc atatagtcca acatctgaag tattcttaac taacactaat
    21841 aatattaact ttatggctat aactactcca ctactagctt ttgcaggaat ttctgttgga
    21901 aacaaaatag aagctttaaa agaaatgtca tggaaaatag ttataatttc acttattgta
    21961 tttacaacta tattctttgc atgtgcgagt atagctcata tagttttaag tattcaaggt
    22021 aaaatatagg aggaatttat tatgaataaa gaacaattaa aatctctagt aataaaaact
    22081 atagatgaaa atagagaaaa aatattaaaa ataggtcaag gaatatacaa aaatccagaa
    22141 tatggatata aagaatttaa aactacagaa gctgtttcaa acttttttga gcaagaatta
    22201 aatttatctg tagaaaaaaa tatagcagtt acaggatgca aagcagatgt aaattctagc
    22261 aagaaaggtc ctcatatatc tatacttgga gaattggatg gtatatcatg taaagaacat
    22321 aaagatgcta atgaaatagg tgcttctcat acttgtggac ataatattca aatagctgga
    22381 atgttaggtg ctgctgttgg tttagtaaaa agtggcgttt tagaacattt agatggtaaa
    22441 gtatctttta tggctactcc tgctgaagag tttattgagt tggaatacag agagcaatta
    22501 aaaaaagaag gaaaaataac ttattttggt ggaaaacaag aattaataaa aagaggttat
    22561 tttgatgata tagacatatc tatgatgttt catgcttctg atttaggaga agataaggct
    22621 ctagttggtc ctgagagtaa tggatttgtt ggaaaaaagg ttaaatttat aggtaaagaa
    22681 tctcatgctg gttctgctcc acatgatgga ataaatgctt taaatgcagc aatgcttgct
    22741 ataaacaacg tgaatgcact tagagaaact tttaaagagt ctgaaagagt tagattccac
    22801 cctatcatca caaaaggtgg agatatagta aatgttgttc ctgctgatgt tcatatggaa
    22861 tcatatgtta gagctagaac tataaatggt atgattgatg ctaatgaaag aataaataag
    22921 gctttgatgg ctggtggaat ggcagttgga gctgatgttg agataactga aattcctgga
    22981 tatcttccaa tattacgata caaaagtctt gataatttat ttaaaaacaa tcttgaagat
    23041 ttaggtctaa aaggaaaagt tattgatggt ggagatttta caggctcttt tgattttgga
    23101 gatgtgtctc atataatgcc tactcttcac cctatgattg gtggtgtaaa aggagctctt
    23161 catacaagag attttgaaat agttgatgaa gatttagctt acataattcc tgctaaagca
    23221 atggcactta cagttgtaga ccttcttttt gataatgcta aggatgctaa agatatatta
    23281 gataccttta ctccagttat gactaaagaa gaatatctaa cattcttaga aaaacacgat
    23341 aaaactttat aagtctattt ttataatagg gtggtatcta ctgtaaaagt tataccactc
    23401 tttgtttttg taacagtata cttcttttct tttagttttt agattaaact aaaatatatt
    23461 atcctcctta aaacttttag agatacgtta aaatatcagt agaactatgc tatattcttt
    23521 ctaattaata taaatttata ttctaattca aggtggtgaa aaaatgttta atgcaggaaa
    23581 tcgaattata aatacatggt tgtaccctat tcaagatggc tttgtcttga ttgatactgg
    23641 atatgaaaat ggttttaaac atttcaaaaa acgaatttct aaattcaaca taaaaatcaa
    23701 agatattcga tacatatttc taactcatgc tcatgatgac catgttggtt ttctaaatca
    23761 gattctagac gaatctccta atacaaagat tgttatgcat gataaagctt tagaaattct
    23821 atataaaggt caaaactctt ttattggtgg ttgtaacagc cgtactgcct ttctcttttg
    23881 ccaaattatg aaactatttg gaaaaggtga gcatagtttt tctccactta aacaagaatt
    23941 tgaaaaaagg tgtattcttg tgtctgacaa gaatcgtaaa gaaattgaaa aagaactaaa
    24001 tggaaaaatt atagatacac caggacatac tgctgattca atttcactac taattgatga
    24061 tggtgtttta ttttgtggag attctgcaat gaatggattt ccaagtactc acaaaattac
    24121 catatttgca gaaagcaaac tagaatttat tcaatcttgg aaaacaatca tcaatacaaa
    24181 acctaaaatg atttatcctg gacatggaaa accatttgaa tacagtaaat tagaacaaaa
    24241 tctaatctat gtaaataaaa taaatttata tcctctacat aattcaaaag atattcacag
    24301 gtttttgtag aaaatacaaa gtaaatttct ttgattaatt aaaaaatcta acactttact
    24361 acgctactta ttttaataac ttaatcttcc actagctttt cataaaattt tgttttaaaa
    24421 ttaactttaa agtgcatatg ctatttaaat acattagata taattcgtca ttaatctact
    24481 taaagcatat ttaactaaca ccactcaacc agaaaattca gaaaactgca ttgacacagg
    24541 aaaaagttta ttttatactt tttttaggac atattgtgga cacgtcttaa atcgacaagc
    24601 agaatttata ttgtaagatt aaccacaata cttatttttt aattatattt ttaaacatta
    24661 gggaggatat tatgaatgat aacgtagtta agaagaaaaa cttttttgac aggacattaa
    24721 acagaataga aactgttggt aataaactac cagacccagt tacaatattt ttagggttat
    24781 gtgtactttt acttatacta tctagtctag ttggttctat ggggatatca gtagttcatc
    24841 ctggtactgg agaaactata actgcagtaa atttattgac tgtagaacag cttcaaattc
    24901 ttttaggaaa catagttagc aatttccaag ggtttgctcc tttgggtcta gttctagtaa
    24961 ctatgatagg tgctggtgta tgtgacaaaa caggacttat gacagcaaca atcaaagcat
    25021 cagtaagcaa gattcctgaa acaagagtaa ctcttgttgt aatgactata ggtatgcttg
    25081 ccaatatagc ttcagatgca ggtacaatat tatttccacc attagctgca cttgtatatc
    25141 ttggtgttgg tagacatcca cttataggtt tattttctgg atatgcagca gtctgtctag
    25201 gatttgccgc aaacattatg ataagtgtca atgatatact tgctgcaagt tttacagttc
    25261 cagcagctca aatgattgat tctggatttc aagccaatgc aacaatgaac ttatttttta
    25321 tgatagcatc aacttttgtt ctaatacttt tggcaacatg ggtaacagaa aaaattgtag
    25381 ctcctagatt tggtaaatat gaaggaaatg cagaactaga tgttgatgga agtcttagtg
    25441 atgtagaaaa gaaagggctt aaaaaagctg gtataagtat attaatatat gtagctatta
    25501 tagtagctct tagtgtaatc ggtaaaaaac cattcttagc tgacccagaa acaggagatt
    25561 tactatcaaa caatgctcct cttatgaaag gtatggtacc tataatagct ctagcatttt
    25621 tcatacctgg tgttgtatac ggaaaaacta taggtaaaat aaagaaggat aaggatgtag
    25681 tctctataat ggctagtgca atgagtgata tgggtggata tataatacta gcatttgctg
    25741 cttcacaatt tttgcaatta ttcacaaata gtaatttagg tctgatacta gctgtaaagg
    25801 gcggagaatt tttaaaatca gcaggaataa atggaccttt attgttgata ggatttatta
    25861 tattatcatg ttttataaat ttatttatag gtagtgcatc tgcaaagtgg gctattcttg
    25921 cacctatatt tgtaccaatg tttatgatgg ttggatacaa tccagcactt actcagatgg
    25981 cttatcgtat aggtgattgt ataacaaatc cacttagccc attatttccg tacttcccta
    26041 ttatactagc attcacaaga aaatacgata aagatgctgg tatgggtact gtaattgcta
    26101 atatgatacc atactctata tcattcttaa tagtgtggac tatactatta atattgttta
    26161 tggtatttaa tattccacta ggacctggaa tacttccttc atatagcatg taatttattt
    26221 aaatctttct aaaaggagaa ataatttatg ttagataaaa atagacttat aaataatttt
    26281 atggatatgg ttagaattga tagcccatct aatcaagaat tagaaatgtc taagtggttg
    26341 gtaaactact taaaagaaag aaatatagat gccattatag atgatgcagg tgaaaaatat
    26401 ggtggtaata caggtaatgt cattgcctat ataaaaggtg aagaaggaag tagaccactt
    26461 tgtttatgtg cacacatgga ccaagttcaa ccttgtttag gtgtaaaacc aatactagat
    26521 ggtaatgtag ttagaagtga tggaactact acacttggtg cagatgataa agctggaata
    26581 gctgctatac ttgaagcttt agaacatgtt actacagaaa aaataccaca tagagatatt
    26641 tatctttgtt ttacaatctg tgaggaagct ggtatgcatg gtgtcaaaaa ctttaatcct
    26701 gacaacttgc cttgtaaaga tatggtgatt ttagattctg gtggagctat tggttcgata
    26761 gcatacaaag ctcctgctca acaatctata aaaatctctt ttcatggaaa gaaagcacat
    26821 gctggtatag aacctgaaaa agggttaaat gctatattag tagcctctca tgcaataagc
    26881 aatatgcaca taggcagaat agattcattg actacttcaa atataggtaa aatagaaggt
    26941 ggtggagcta caaacatagt aactgataag gttacattga ctgctgaaat taggtctcat
    27001 atacctgaaa ctttagagta tgagcttaat catatggaaa aatgttgtaa ggatgctgca
    27061 tctaaattta atactactta tacctttgaa catagtatgt cttaccctag ttttgaactt
    27121 agtagagata gtcacgtttt caagttaagt gaagaagcaa taagacaagt tggtgttgtt
    27181 ccaaatccaa tggtaattgg tggtggaagt gacgcaaata tattagctaa tcttggatat
    27241 aattgtgcta tattaagtct aggtatgtat gatgtacaca cagttaatga atatgtaaat
    27301 atagacgaat tatatgatac tgccaaaata gtttatcata tgattaaatt ataaatatca
    27361 taatataact ctttaaatta taaaaataaa aacctatgta tcttcaactt tataagttat
    27421 atattaaagt tgttttacat aggttttagt atcttatata ataatttatt ttaacatttt
    27481 tcataataag ctttggtatt ttatatagta atttgttcta acatttttca taataagctt
    27541 caatattttt cataataatt tgttctagca tttttaataa caggctctag tattttatat
    27601 taataattta ttctagcatt tttaataaca agttctagta tttttaataa caagctctag
    27661 tattttatat aataatttgt tctaattttt ttcatgataa gctttaatac tttatatagt
    27721 aatttgttgt agaattttat aaaatataat gatttataca gttttataaa atatcttaaa
    27781 acagtatttc agtaatattt tttggtcttc ctccaccaat actagtctct tttgcacata
    27841 ttcgacctaa acctgcattt actattttat ttaatatacg tcttgcactt ctttcactta
    27901 catttagata ctctgctaac tcttttgaat cataaatctt actttttcta ttctcactta
    27961 tagcaataat ttttgcaact gactcacaac tcattccagt ctttttagat atttctatta
    28021 ccttttcatc agatagcatc aaagaataat ttaattcatt ttcggaagct aaaggtcctc
    28081 ttatattttc atcttcatct accaaatata taccaatttc ttttgaatct atggagtgtc
    28141 ttaatgcttt atgtgcatta ttttcagcct gatacgcagt tactccagta ccaattccta
    28201 tactaagaga aaagcccatg tcttttatct ctctctttag attgaatagc ttatcataat
    28261 tatactcatt atcagctacc cctttatgaa caaatacaac ataatcattt cttccaagta
    28321 aaaataagga accttgaatg cttcttacat agtttactac aagcttatcc atatctgatt
    28381 tttttatcat gtcagaataa tagttatcta tcttctcttt ataatctatt agactcaata
    28441 tttcgacagc aatttgagaa aatcttgcct tgcttagagc atattcactc tttaccttat
    28501 cataactttc tttgattaat tgtatagtag cttgtaaacg aaatacagga tagcctcttt
    28561 cttttaattc attatatact gcaccaaaac cagttaacat tatatccgtc ttattttctt
    28621 caaataattt tatatgccat tctacaagtt cagactctcc tacttccaaa gaaaatggat
    28681 tacaaaatac actcgttgct ttaatatcaa attctttaag tgcatcttcc acaacatatc
    28741 tatcaactac atctatactg aatttatcta attttatatt tgcacttttt attgcccaaa
    28801 atgccttcat tatactcgtc ccacttctcg gtacaaatga atgtggctta cttatctcat
    28861 acttagattt tataaattca taaactgcac atcctgtaaa tataatagca tcacattcat
    28921 cttcacattt agaaataact tctattgtat ctactacttt ttctcttaca tatattttag
    28981 tctttaaatc actgtctatc tgttttaaat catcctttat cttaaaccca gagtctgaag
    29041 gacctataat acccactatc ataaacttcg ctcctaatcc ataaatatta tactttttaa
    29101 aaattatatc ctcactattt tctacttcta tttaattatg ttgaactact ccatcctacc
    29161 tacatttaga gtgggataat tagcttattt ttgataaagt aacttctcaa aatcagcact
    29221 tggaataggc ttacaataat aataaccttg aattaccaca caatctaaac tcactaaaaa
    29281 ttcagcttgt tcttttgtct ctacaccttc tgccactaca tccatatcta aatcttttgc
    29341 catggctata gtgtgcctta aaactatttt ttctctgtct gtgattcctt cctcattaaa
    29401 gaagccacaa tctatcttta atgtatcaat attaatattt tttaacatat ttaatgaaga
    29461 atatgctgaa ccaaagtcat ccatatttaa aacaatacca tccattctaa ggtcggctat
    29521 tatcttagta aataatttta tatttttaat aaataaactt tctgtaagct ccaattctaa
    29581 aaaagatttt ggtatactat atttatttat taaacttaaa acaatttctt taaaatgtgg
    29641 attatgcaaa tgtaatcttg atacatttac agagatagga actggctctt cacctaaatc
    29701 tatccatttt ctaatcaaag aacatacttg ttcccacaca tacatgtcta atctgataat
    29761 aaacccattc ttctcaaata gtgaaataaa tttaattgga ggtattatac ctttttctgg
    29821 atgaacccat ctaaccaatg cttccgcacc aacaatttta tttgcattaa gattatactt
    29881 aggttgtaga tatacatgga attgcccatt ttcaagtgcg tattccattt ccctttccat
    29941 ctgtttttct tcaagtgcat catttcttat agtatcatca taaaatatat agttattgat
    30001 actttgtttc tttacttttt tgtgagcata tcctgccatt tcacacgcat ttgtaattgg
    30061 gatattatta tccaaaattt tataaacccc aaaacatggt actaacatat attcaaattt
    30121 ttttctattt aagctatttt taatcttata aattaattta tgaacatctt tatcagagta
    30181 actctcataa aaaatacaaa atacatctgc atacatacga caacatatac cattagaacc
    30241 aatgtttttt tgaatcaatt ctgcaacata tattaaagcc ttatctcctc ctctaactcc
    30301 ataaatgtca ttaattacct tgaacttatc tatatccatc attataattg catagctctt
    30361 gtcaggatat cttttaagca ttaaacttgt ttgttcacaa aaactttcat aattgtatag
    30421 tcctgttaat atatcctttt ggtttttatg tagttgcata agataatcta tattttttat
    30481 agcaactaaa atatgtgttt gtttctcacc taacttattt ttactactaa tctttaacat
    30541 ataaattaat gcccaatagt actttttatc tattcctaaa cgtctatact caaaatttag
    30601 ttctaaatcg tcttgcttgc tgttattaag actatcaaga gattttagaa ggtggttatc
    30661 atcaaataat attatatcat caggatgaat taaatgtttt tttatgtatg aaaaagtttt
    30721 ttcaagattt tcctttatag gaaaactaaa aatattgctc tctgattgat aaattggagt
    30781 aattaaatta gtatcgatgc aaatagataa aattatatca tatgtattat aagctaattt
    30841 ttcataagcc ttagaatacc cttttatcat taaatcatca aaataaacct tatcaactaa
    30901 ctctttatgt ttaaataaaa tattattcgt cgaatcagct aagtcactaa ttacttccat
    30961 ttcattattt ctaagtttgt tcttattata atacctcttc ttatcttggt acattctctc
    31021 atcagcaact ttaattagct tatgtatatc aatattatcg tcactccaaa tactgcccac
    31081 tgctacacta tatatcatct catccttaaa ttcttcactt aaccaactca ctaattcttc
    31141 aaatagttgt tttgatatat cttcacataa tacaacaaac tcatctcctc caatacggta
    31201 aacattataa gaatgaaagt atttttttat tattacacat gctgacacaa tagcagagtc
    31261 gccattagca tgtccaaagt tatcattaat atcttttaac ccatttatat ctacaaatac
    31321 aactcctatg gatttaactt ttcctttttg aaaattatct atatacttaa tatatttgtt
    31381 tctattatat gcaccagtca agaagtcata gtagctcata taatttaatt tattttctac
    31441 ttttcttttt ttcatctcag ttaataaaaa ataagatagg gatgtcaaaa gagaggtatc
    31501 tccaacagcc ttatgtggat tatcaactcc aataaaccct actactttat catcttgttt
    31561 tagtgaagat gtcattaaac tttcaatttt ttgaggtttt aaaatttcat attctattgg
    31621 ctgttcttct tttatatttt ctatatcatc aattattaca aaaccctttt gttcgaataa
    31681 taaaaaccaa ttctttaatt cattaatatc aagatttgtt agtgcctgtt tttgttcatc
    31741 aacaccttca ttgcaccatt catatgtatt agttactttt tttctatctt ctgatacttc
    31801 aaaaacatat gctctatcag ctttatgaaa tttaccaata ttggttaata caagatttac
    31861 agcatcagaa aaattagatt ctgttataag atgtttaata catccaacta ataactcctt
    31921 tatctctaat ttttctgcta ttgacttact tatatcttcc ttttctgtaa tatcaagagc
    31981 tatttctaat cgtgcatgtt tgccctccca tttaattaac ttgtccttta atataaaatg
    32041 tctatttgtt cgagtattcg tattttccca tatgtaatat tcatcttctt ttaaaataga
    32101 gtttgtacaa aattcgcagg gagaatcttt cccctgtaat gctttataac attttacatg
    32161 ggatatatca ttaattccca ttgccttttt cccaatttca ttaatatata aaagttcata
    32221 tgtatctaaa gaagaaacat atacaatttc atccaactca tctattaaat ttattacatc
    32281 catttatata tatctccttt tattcatttt ccagattgaa tttttaaagc ttttaaaatt
    32341 ttgctatata tttggcaatg atattatact tctttatgtt ttaaaatagt accttaataa
    32401 agttctattt tttagtaaat agaattatta ttgtgtcaat cgtacaatag agttttgtaa
    32461 tacctaattt aatatattta taattaacta tcttattatg tgtttacaat taattctcat
    32521 ataaatgaca aatctccacc tcaattaagt attccaatca tatatgaaga taatacttca
    32581 ttcatttaaa aatataaaac tattatatat taaaatttct tcaataataa attatctaga
    32641 ttgttacttt gatatattat ataatatcac aaaggctgat ataaaaagac aaaaagggca
    32701 atttttttat atcaaaaaaa aatgttaaat tgatattatc catatagatg ctatatttaa
    32761 caattctact tacttccctt acacttatta gcatatagtt attaagagtt tgttgcaaaa
    32821 caacacttag cacactttaa aaagtgtggt ctaataagta atcaacgaag aagacataat
    32881 aaagcataaa atatgatata cttttccatg tcatcaaaac tgatgatttt actattaata
    32941 tctgctaaaa tatacttaat aaattaaatt ttaatgggag aatagttatg aaaatattta
    33001 gtttcttgtt atttgtagtg ggaatatgtt tttgtattgc tggatttatg ggacattacc
    33061 cagcatttgc tggtgcaaca ttgagttttt ttgcaactac aatgatagct gtaagacaag
    33121 tcaaaactaa gaaaaaatga aataggcaaa tcctaacttt acaagttaat attacataag
    33181 taattagtct aaaattggat actttttcta ttacagaaat acatcatcca ctttgtattc
    33241 tcttaaaaaa ataaaatagc tatgtaaatt caagattaga tagattaact ctctatccat
    33301 ttcattgtaa aatatacata gctatttgta ttcgatttaa aatacttaga ttttcttaca
    33361 taacaaataa tttctatctg attattactc atattcattt ggtaatcact cagcaactaa
    33421 tcatttagta tctattcatc cgccatacgg taacctaccc caacctcagt caaaatatat
    33481 tctggctgag caggattctt ttcaattttc cttcttatac ttgccataaa aactctaagc
    33541 gactgatttt cactttcata gtaatttccc caaactttat ctattataaa cttatgagtt
    33601 aagactcttc ctgaatactt agacatcaac tcaataatct tatattcgat tggagttaaa
    33661 tgtatttctt caccattaat tgacacaata tgattttcat aatctatctt taggttttta
    33721 acttcaaaag actttggagc atcattattt atattatcct gttgagcttt atttctaaga
    33781 gccacacgta ctctagccaa aagctctgtt acactaaaag gtttagttaa ataatcgtct
    33841 gctcctccat ctaaagcttc caccttatcc ctctcatgct ctctcgctga aacaacaatt
    33901 attttattag tctttgcaca tgccctaact cgtcctatta cctcaatccc atcaatatct
    33961 ggtagtccta aatccaaaat tatcaaatct gggtcaagag aatgtataag tgatatagct
    34021 gttcctccat tatctgtctc tacacaccta taattttgag tttcaagaga tacttttata
    34081 aatttacaaa ttggcttatc atcttctaca attagaacta atggctttat ttccacttgt
    34141 ctttcccctc ctcatcatac ataggtatgc taaatctaaa tgtagctcct ccagaaggat
    34201 tattaaatgc gacaatttct ccaccatgag cttctactat agatttacat atctccaatc
    34261 caagaccaat acctcttctt tcaagatttc tagacttatt cttagtataa aacctattaa
    34321 aaatattacc gatatcttca tttggtattc cttttccatt atctgcaact tcaaatagca
    34381 cttgatttga ctcttttttt acagttagtt ctatcttaga atttttaggt gtatgcctta
    34441 tagcattatc aattaaattt actaacactt gttctattaa taatacatcc acatgaacga
    34501 ttattatctc atctggaata ttggttttta tgtctctact attggcaaac tttttgactc
    34561 ttaatataga ttcagctatt atttcatcaa caacttctgg tcgtttttca atatccaatt
    34621 tcccttcatc tattctagtc atactaagta tattctcaac agaatgagtt agccaactcg
    34681 tatcttcata tatatttttc aataattcta ctctagtttc tttatctatc acatcatcat
    34741 tttcaagtat tgttgaagac gaacccaata tacttgtaag tggagttctt aaatcatgag
    34801 aaattgacct aagcaaattt cctcttaatc tctctctctc tgcctcaaga tttgcttttt
    34861 tatttttctc aaataaattt tctctatcaa ttgccaacgc aacctgtgtt gaaactgctt
    34921 ctaatagtat cttttcattt tctgtaataa tatctatctt aaaacacgca acacctataa
    34981 caccaagaac atttgattct tgacctttta tagggaaata atatgcactg ctgtttttgc
    35041 aatattttgt cccaattcca actgggttac ctgtcctaaa agcttctttt atagcttctt
    35101 tttctaatac tgaatggaat atattctcac ttccatcatt gttacaaata taaatacttg
    35161 gcttacctag attattattc tcatctgcaa tagtcactat tacagttcta tttaatatat
    35221 ttactaaatt agacccacaa aattcaataa tttgattttt attttttgct ttaagcaacg
    35281 ttttgttatt ctcatagagc aatcttatca ttttttctct cttatgagaa agtctcactt
    35341 ctctttttat cctagaagtt aaagtacttg ttataattgc tgccattagc ataatacaaa
    35401 aagtcatagg ataatctttt ctataagcta aaaaagtata taatggatgc gtaaagaaaa
    35461 aattaaatga tagcactcct attactgaag aaagtattcc aaaaaaatat ccataggtta
    35521 tacttgtagc aaatagtaca cctaatatgt atactagtat aatattagat tcattaaaac
    35581 ctaccttttc aaaaactact gatattccag tagcaattgt cataaccaat atagttttta
    35641 tgaagtcctt aataattatc tttttactga gatagccatc ttcatcataa tcatactctt
    35701 ttaagtcttc atgttgtagt cgttcctttt tcatttacta caattcctcc ttattgttac
    35761 tgtttaaatt ggctctattt tatataatac aattttatca taataaattc aatcaataca
    35821 tttaattaat gtacttaaat tactaaaagg tgctgtctta aaatgaaaat aaatctctat
    35881 ttcaaaacag cacctatata tttaaattac taatttagtt tttacatact taaatcaata
    35941 gttttattca attttataaa ttataatact tcaattatgg aacatttcta tccaacaagc
    36001 ataaatataa agtgggcaca tatacctgca cacaagccac ctatggtatg cgaaagtatc
    36061 gctttaccag ccaatggtct tgcatctaaa gcatccatca tacctatgtg tgtacttaaa
    36121 tatccactcc aacacatacc cattgctgtg aatactgcta tatcattagg agttatagcg
    36181 cctgatttta taaactctgg tactaaagat attgctgctc caacagctcc taatgcagtt
    36241 acagggaatg ctattgcctc tggtgatgtg aatccaaata atggttctat tatgaagcta
    36301 atcttatcac caatagcagg taataatttt ataccttcat atgcagctcc tgtgtaaaca
    36361 gcttgacctg tagcagggtc tgtagatggt ccaaaagtta ataacataac taatgtacaa
    36421 actactaaaa ctcctggtat tatagccata cccatttcaa cacctagctt accaccttca
    36481 agtatagcat ccaatgttct ttggaataca ttaccatctc ttatttctct aaactcttca
    36541 agttttgcac ctttatcatt tatttgcttt tcagtatcat ttttagggtc ataattataa
    36601 tactttttag taaaagtcaa cataattcta acactaataa tactacctat tattgcccca
    36661 acattaccta ttatagctgg tagtacatat tctttacctt gagctatcat aaaagttgtt
    36721 acaataagtc ccataccaaa ggctgttcct aaattacata aagcaggtac ttgatacttc
    36781 ttaaaatatt gtgtaaatgt tttgtcttta gcaaatggta taatagctgg attatcagat
    36841 aaatatgttg caactactcc tgctatacta gcaccaggta agccccatat aggtctcata
    36901 agacccttaa atatcttatt aactaaagat attactccaa actctgaaag caacgcacta
    36961 agtgcacctg caagaactgc catagccatt attaaaaata ctgtgtctaa taaaagcgca
    37021 tgtgctgtac tcattattac tttaaacatc attcctgcac ccatgatgct tcctacatat
    37081 ccaaatccta ccgccaatag tacaataaat acgaaggttt ccatacttac tgccttgact
    37141 cttctcttat ccgacagctt ttccatcttg aaatcttccc ccttttaatt ttaaattaag
    37201 gttcctaaca ttggtacaaa ttttttggta caaactgagt tctaaaactt acactcgtaa
    37261 tgcaagttgt cagttttttg aaataaaaaa aaattacgtt tatagaataa gaatatcctc
    37321 tttaatttgg atactcttat tctattttat gttattatat tatcatcctt ttgtttaaaa
    37381 gtcaattttt tctatttttg ttgtttaatt ttatttatac tctttttata tttttcattt
    37441 tcttttatct ttgtaagcac tccatataag ttgacttttc taaatacagt agttataaat
    37501 accaatccta atgcaattga acttgcacat gataatgtac tcaccccata ttctacagct
    37561 tttatataat tattggtcaa aacagaatac atagtattat atattccata accaggtact
    37621 aatattatta aacaacaaac acttaatgta gttgctggag tcatataaat tcttgcacat
    37681 aactcacaat atatcgcaaa acaaactgta gctataaaaa aacataagtt ttctgttact
    37741 cccatattta aaagaaattt atatgaaaac caagctatac ttccacctat tcctgctagt
    37801 attaagtttt ttcctttcat attaaatagc actccaaagc ttaaggcagt aaaaaaagct
    37861 gctattactt ctataaacaa atgcacttat atccccccta acttgaagta taatccaagt
    37921 accaagaaca ttcctactgc tatagataca cctacaaaaa atacttctgc taattttgca
    37981 agaccagaaa tcaactgtcc atctaacaaa tctcttaatg cattagtcaa agcaagcccg
    38041 ggaactaaga gcattattgc tcctgctatt aaatggtcta acgtctttat gaatccgagc
    38101 tttaaaatta aaattgaaca agaagctata ataactgctc caattgcatt tacaaaaaag
    38161 tcattaaggg aagatttact taaatacata ataacaaact tagtcagaat cccaacagta
    38221 aatgcagcta taaattcttc cacatttcct ccaaataata tcgaaaaagt tgctgctgca
    38281 atacctgcaa aaaatattgt tattaaatcc gagtaatagt tatcttcact tatttcatct
    38341 aaaattttct cacataattc aatatctaaa ttatttatac ttattgctct tgataatgag
    38401 ttaacttcat gaaccaagtt taggtctact cttcttgagc ttattctttt aattgctgaa
    38461 tgtaatttcc catctacaaa tacagatgcc attacagctg ttggagttgc aaatacatct
    38521 acgtggtcta ttccaaaaga ttgacatatt ctagctatcg tttcttcaac tctataggtt
    38581 tctcctccac tttgcaacat agctttacct gcatttgagg aaaagtttaa aattctatct
    38641 atatccacaa aacatatctc ccattctttt atagtattat tcatatttta atacaagata
    38701 ttatttattt aaactatttt aaataattca tatccaatat ttacatttta tgaaaaaact
    38761 tgttttttat gcttgtcaaa atcaaatttt aagcttgttt acaccataaa atggctgaat
    38821 taatatttga caaacacttt caaccattta tataaccttc taaattgtat aactttttac
    38881 tacaaataaa attatatctc ttttaattct ttctcttgag tatttaagct tatagcaact
    38941 tcatatttat atatgtacaa tataaaacat tatttttatg atacaaaata taatttgtaa
    39001 atgtatatat gtattaactg tgtatatata aattattctt aaccttatca gttttttcat
    39061 atatcttcat ctatatcgac catatattaa ttacattgac catatattaa taaatgatat
    39121 tacatagact gaagtatatt aaaaaactta aatttagtta tttaacaaca taatactcta
    39181 atttaatcta taaaaatcca tacctaatat aatgcaactc ttattttaac accatatatt
    39241 acacaaaaca acatattaaa aagtaaaata caaaatatcc actataaacc ttattttaat
    39301 actgaatata tattataata tatttaatgt agcttaaata tagtttaaac ataaagaaag
    39361 gaaacggtat atgctaagaa aagataaagt tctattatct ctacataaat tatgtgaaaa
    39421 tatgacttta aaagaccttc aatcagataa aacaggattc actacaatag aaattgctaa
    39481 ccattcatct cttgatagaa gtaataccag taaagaatta aataacctat acaatgaaaa
    39541 aaaagttctg aaaatatctg gtaagccaat tttatttcta catgctagta ttatagaaaa
    39601 tttaattggc cgtactttga acagtgatga attttctata aataattgta atgagctact
    39661 taaatcaagt aaaaatgact cagaagatat tttttcaaca ttacttggac atgattctag
    39721 tcttaaacta cctatagaaa aagctaaatc tgctatactc tatcctccaa aaggtcttaa
    39781 tacattactc ataggaccta ctggtgttgg aaaaagtaca tttgccgaaa caatgtacaa
    39841 atatgctgta gaaagtaaaa tcttttcttc tgaaagcaaa ttcgtagtat ttaactgtgc
    39901 tgaatatgca gaaaatgcta acttattatt aagtaattta tttggttatg tcaaaggttc
    39961 ttttactggt gctaataagg ataaattcgg catagttgca caggctgatg gaggcatatt
    40021 attcttagat gaaatacaca gattaccacc agaaggtcaa gagatgcttt ttcttttgat
    40081 ggacaaaggc atatacagac gattaggaga atctgacatt gtgcacaaag ctaatgtctt
    40141 tattgtgtgt gccacaacag aagatataca ttcttctctg cttgggactt ttttaagaag
    40201 aatccctgtt acaatcaacc tacctgcttt acaggatagg tctttaaaag aaagattatc
    40261 tcttattaaa tacttcttta ttatagaatc aaaatacacc aatgcaacta taaaagttca
    40321 caaagatgta attaaatcat tactccttta tgattgtttt ggtaatatag gtcagcttaa
    40381 atctgacata caacttatga gtgcaagagc ctttttaaat tacaaaactg gacttaagga
    40441 taatatagaa atagatttat cccttgttcc tgattacatc tatattggtc ttttaaaatt
    40501 gaatgaaaat cgtagtaatc taaataaatt atcagaactt gattatatgc ttttttatga
    40561 atttaatggt aataacttag aagttgaata tacaaaagaa ctatctaaat acaatataga
    40621 tacatcaaac aatggattta aatactctac agagattcct tatctggaaa atgatataag
    40681 gagtatgttt ataaattaca tggaaaagta ctctacaaaa ttactttcga tatcttcagt
    40741 aactcattct gattatacaa gtaatgaaat ttttaaagta atcaatccaa agatttacta
    40801 tgctgttgaa cattctttaa aagaggccga aaaaatatcg agaaacaaat acacaaaaca
    40861 aacttatatt gctctttcaa tgcatataag tgcacttata gaaaatataa atcaagacac
    40921 ctataatcct aagtacaatt tatataatga taaaattttc ttagataaag atttaaatat
    40981 agctaaaata gttttaagta taattgaaaa tgacttacaa acatctttac ctaaagatga
    41041 agtaaaattt atatccatgt ttctaaatag catgtatctt gaaccaaaca atcaatctga
    41101 aagtatagga gtcataatac ttgctcatgg aaattcaaca gcaagcagta tgtgtgatgt
    41161 agcaaattca ttgcttggta caaaccattg taatgcaatt gacatgcctc ttgatgtaaa
    41221 agtaagtacc atacttgata aaactataga gttggtaaaa gaatgtgacg aaggtaaggg
    41281 tgtacttctt ttaacagata tgggctctct tatagctttt ggagaactta tttcagaaaa
    41341 aacaaaaatc aaaactcgct caattgaaat ggtatctact ccaatagttt tagaagcagt
    41401 aagaaaaagt acactaccag aaatgacttt ggatgaatta gctaattcct taagctcttt
    41461 aaatccatat attggacgag cagcaatcga ttcaacagaa ataaactatc ctgaaaagtc
    41521 aagagagtat gtaataataa ctacttgtat aacaggatat ggttcagcta tgaaagtagc
    41581 agactttata aattcttcac ttaaaaatat tagtaaatac aatattaatt tagttcctca
    41641 taatatagaa agttttaaaa tgtataagaa taaatttagt aatactaaaa ttctggcagt
    41701 tgttggaagt gtagatttta atgtagccaa cacccctttt atacacatag aggaactact
    41761 aaatggatat ggcctagata tgctaaacaa aataatagaa ggtacattca atgccaatag
    41821 tattacaaat ataaaagaaa caaatctatc atacaacagt ttaataataa actttatgac
    41881 ccaaaactta gagcttttgg actctgttaa attattcaac tatgtcaatt cttccttatt
    41941 tacaataata gaattaatag atgaaaactt aaagagcaaa tttaagctag gatatatact
    42001 acattgttct tttatgatag aaagatgttt taaaaataca acttttccat ataataacat
    42061 tactgaatta attagtaaaa atcatgaact atatagttta atacgtgaag cctttaagcc
    42121 aacagaagct tattttaata ttttgatacc agacgaagaa attgcttata taatagacat
    42181 gattaatgag tatctaaata aataaaattt atagcactta ttttgtgcat attaattaat
    42241 atatgaaatg gaggacgaga ttttgaaagg aaaaataaaa cagttaacaa tacttacatt
    42301 aatttttata tttataactc ctgtatttgc atttgcagat actccaccag taccaaactc
    42361 ttcaagagca gcactactta tagaccagga aactaaaaga atattatttg aaaaaaatat
    42421 tgatgaaaaa atgccattag cgagtttaag taaaatgatg acctttttat tggcaataga
    42481 agcagttgat aagaatcaag taaaagagac tgatatggtg aaaatagaca agtctacagc
    42541 ttcagtagga ggttctactt gtaaacttaa agatggtgat gaaatatctc taggagagct
    42601 tatgcagggt ctaatgctag tatctggaaa tgatgctgct atagccatag ctaaacatat
    42661 tggtaaaact gaaaagaatt ttgtaaatat gatgaacaag aaagcagaag aaataggaat
    42721 gattgatacg tattatttta atccaaatgg gcttcctata tatactgacc cagaacataa
    42781 agaacctcct attgaaaata tgtcaactgc tcacgatata gttacacttg gaaagtatat
    42841 gtacgaccat tatgaaaatc aagttacaag aataaccact atgcaagtat ataatgatac
    42901 taaaaaggat tttacacatt ataacacaaa tcccctactt gtttcagtac ctggtgttga
    42961 tggaataaag acaggctata cagataatgc tggatattgc cttgcatttt ctatgatggt
    43021 acctaaagat gctaaaaacg aaagaaatca tagattgata ggtgttgtac ttggtgatgg
    43081 taacaagaaa aatagaattt cttcttccgc tactttattg aaatatggta aagataattt
    43141 ccattctaaa aagatagcac ataagggtga tattatagag actccttgtg ttgatggtat
    43201 tgatgatttt aagataacag ttaaggttga taaagatttg tatggtgttg tttcagatag
    43261 cgagaatatc aatcctaagg tagtgtttaa aaatatgaat tatcctatcc ataagggaga
    43321 tattgttggt gttgcaaagt attataatga ttctggtaag tttgttggaa gtgttgatgt
    43381 aaaaagtgaa agtaatatag gatgtattcc tttgaaggat aagattaaga ttaaggttgc
    43441 taagataaat aaaaaacttg agattaaaaa ttctgtttgt tttaaagtat agtaaagcat
    43501 actattaaaa gagtatatta aatttataaa tactccactt tgtggagttt ttttgttttt
    43561 tacaaaaaat taaaatagtg gcaacaattg aggatgtgag ggagagttgc cactattttg
    43621 tatagggtat tatattatgt ttttaagcta gttttactat cttctatgtt tatataataa
    43681 ctcttgtgtg tgaatttaat tgataattaa tatgaaaatt atgtgaagtt ttgatattag
    43741 gttatacttt gaactttatc taacatttta aattttatat ctctaaatta tctaaaatta
    43801 ctatatcaat taactttaca tgataaaaag gctgtgtata aatttatttt taaaaatttt
    43861 actcacagcc ttaaattaaa ttttctattt aaagtgtata taaattttat taaataattt
    43921 gctttttatt tcttatttca taaatcctag tattcttgat aacattaatg caattgtagt
    43981 aggtactttc cctgcttcaa atgtagctgt tgctgtgttt aatgctgtta ctgcatcatc
    44041 tatttctttt tgtgttgcat ctgctttatc taatattgct tgtgcttcat ctattgctgt
    44101 tttatatgt
//
LOCUS       DACTZW010000029        44057 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.029, whole genome shotgun sequence.
ACCESSION   DACTZW010000029 DACTZW010000000
VERSION     DACTZW010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 44057)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44057)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44057
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.029"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(170..943)
                     /locus_tag="JAM15_08220"
     CDS             complement(170..943)
                     /locus_tag="JAM15_08220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SigB/SigF/SigG family RNA polymerase sigma
                     factor"
                     /protein_id="HAT6798234.1"
                     /translation="MKNVANATHYLNMDTKELFNLYNKNKNVDIRNILIERHLYLARL
                     LAKKYINKGVDFEDIYQVASLALIYAIDRYDVEKGFEFSSFATPTIVGEIKKYFRDKV
                     WTLRVPRRIQELSKKISDAKIKLEQENKKHPKVKDIADYIGVSEEDVLEAMEASYGYQ
                     PMSLDSSSNDDSEDKDITLIDKIGKEEGNFGSIEYEDFINKFIETLNELEVKIFKDRF
                     FFDKTQSSIAKELGISQMTVSRLEKKVVEKLKKEYEKNL"
     gene            complement(943..1350)
                     /locus_tag="JAM15_08225"
     CDS             complement(943..1350)
                     /locus_tag="JAM15_08225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HAT6798235.1"
                     /translation="MACETIKMEITTNPDYVSIIRLTASGIANKMGFPIDDIEDIKVA
                     VSEACTNAIKHSKDDVFNIVFNILDNAINIEIQDNGKGYDVSSISTPDLENPKESGLG
                     LFIIKTLMDDVDIESEHNQGTKIKMTKYLGVDI"
     gene            complement(1354..1671)
                     /locus_tag="JAM15_08230"
     CDS             complement(1354..1671)
                     /locus_tag="JAM15_08230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STAS domain-containing protein"
                     /protein_id="HAT6798236.1"
                     /translation="MSMNIDSNLDSQNKFWNVCLDGELDVSTADKLKEHLHALIEKNM
                     LDVKINLKDLDYIDSTGLGAMIGVLKKLKINEKEIYIVNPKSNVKKIFTITGLDKIFK
                     VEG"
     gene            complement(1683..1943)
                     /locus_tag="JAM15_08235"
     CDS             complement(1683..1943)
                     /locus_tag="JAM15_08235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HAT6798237.1"
                     /translation="MNAWGWQIGAVLVGSSALIVAIYLAKTLNSINKVVEKAYKIVDY
                     NERHIQDIVENASSISKGIDDIVYVINKILSIGNIFKIIKRK"
     gene            complement(1943..2239)
                     /locus_tag="JAM15_08240"
     CDS             complement(1943..2239)
                     /locus_tag="JAM15_08240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAT6798238.1"
                     /translation="MCNKRSCKKGGFLLLGAILGFIFGMFFAPKKGSELRKETKEKFN
                     DVKENPKEVLHETFNDVKERIINLVDDDNNEEDIKISEEDIVISKSFDDEGDVN"
     gene            complement(2308..4734)
                     /gene="gyrA"
                     /locus_tag="JAM15_08245"
     CDS             complement(2308..4734)
                     /gene="gyrA"
                     /locus_tag="JAM15_08245"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HAT6798239.1"
                     /translation="MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVH
                     RRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHGDTAVYYAMVRMAQDFSTRALLV
                     DGHGNFGSVDGDSPAAMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA
                     RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPT
                     AAIIMGKESIAEAYRTGRGKVKVRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIA
                     ELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYKHSQMEDTFSIIMLA
                     LVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVI
                     SLIRASKTGQEAKIGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKIN
                     RLKEILADERLLLNVIKDEITIIKENYSDERRTEIRHAEGEIDMRDLISDEEIAITLT
                     HFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNKGRVFKL
                     NAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKR
                     EEFKNINKSGLIAIGLRDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTA
                     MGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRTNIEEYRSQIRAGKGIKTYNI
                     SEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVV
                     SIAKINIEEE"
     gene            complement(4754..6655)
                     /gene="gyrB"
                     /locus_tag="JAM15_08250"
     CDS             complement(4754..6655)
                     /gene="gyrB"
                     /locus_tag="JAM15_08250"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HAT6798240.1"
                     /translation="MKQEYGASQIQVLEGLEAVRKRPGMYIGSTSPRGLHHLVYEVVD
                     NSIDEALQGYCSDIYVSINEDGSVLVKDNGRGIPVEIHPKTGKSTLETVLTNLHAGGK
                     FGGGGYKVSGGLHGVGVSVVNALSKWMVAEVYLNGKIYKQTYEKGLPTSKLEVVGESQ
                     DKGTMIQFMPDETIFDEIEFKYETLEYRLRELSFLNKGIKIVFEDKREGQEKRKEFHY
                     TGGLVEYIKYLNKSRTGIHDDIVYIDKKVDDCFVELAMQYTDGYTENIYSFANNINTH
                     EGGSHLSGFKAALTKTVNDYAKRNKFLKENDVNLLGEDIREGLTAVVSVKLPEPQFEG
                     QTKTKLGNSFMRGIVDSVTVDELGSFLEENPSTARIIVDKALRAQRAREAAKKARELT
                     RRKSVLESTSLPGKLADCAEKDPSKSEIFLVEGDSAGGSAKQGRDRNSQAILPLRGKI
                     LNVEKSRLDRILSSDEIKNMITAYGCGIGEDFDIDKARYHKIIIMTDADVDGAHIRTL
                     LLTFFFRYMRPLIDEGYVYAAQPPLYKVTKQKKEHYVYSDKELNILLDEIGRNGVELQ
                     RYKGLGEMNAEQLWETTMNPETRTLLQVTVEDAAIADEVFSMLMGDKVAPRKEFIEEN
                     ARFVRNLDI"
     gene            complement(6656..7771)
                     /gene="recF"
                     /locus_tag="JAM15_08255"
     CDS             complement(6656..7771)
                     /gene="recF"
                     /locus_tag="JAM15_08255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HAT6798241.1"
                     /translation="MKLKSLQLVNFRNYKKLHLEFNGKVNLLVGKNGQGKTNIVESIY
                     MLSFGKSFRTNKDKEMVRFNSENLYIGGSFSKYNKYSLIELIIGKDKKGIRINKVPLQ
                     KIQELLGNLNVVIFSPEDLRLVKEGPKERRAFIDKEISQIIPKYYKYLTNYNKTLSQR
                     SRVLKNIHVDEALLDVYDDTLAKYGSYIYILRRDFIKKIANISENMHMNLTNGVERLS
                     IRYKNQINITDEDTIDTVYNKFLAKLSSNRPNDIESKTTRYGIHKDDLNIFINDLDAR
                     LFGSQGQQRTASISLKLSEIELIKNEVEEYPVLILDDVFSELDEARQKLLVNNLSNVQ
                     MFITSAEVSHKKIFDEKNVTIFNIENGDVISIENGGN"
     gene            complement(7789..7995)
                     /gene="yaaA"
                     /locus_tag="JAM15_08260"
     CDS             complement(7789..7995)
                     /gene="yaaA"
                     /locus_tag="JAM15_08260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HAT6798242.1"
                     /translation="MTEITIESEYIKLDQFLKLAEIASTGGHAKFLIQEGLVTVNDEI
                     ELRRGKKIKSGDIVKIEGTKIKVL"
     gene            complement(8132..9238)
                     /locus_tag="JAM15_08265"
     CDS             complement(8132..9238)
                     /locus_tag="JAM15_08265"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HAT6798243.1"
                     /translation="MKIICNQKILANRIGIAQKAINGKTTIELLKGILISTEEGQLKL
                     TGYDAEIGIETYVQAEIIEKGDVVVDARLFGDIIRKLPDSFVEIETDSENNIYINCVN
                     SRFKIKGYAAKEFPKLPELNEEDLYSIPQEILKNMIKQTVFAISQDQTKPVLMGELLE
                     IVDRNLNLVAIDGYRLAVKSCSVDSLTENIKVIIPGKTLIDVNSLLSGEDNVKVGFNE
                     KNAIFIINDTKIITRLLEGDFIDYKKLLPREHNSRVKLNTKELLNSIERASLLSQSEK
                     NNLIKLSIRDKVMAITSNTEKGNVYEEVEIDLDGDYLDIAFNSRYFIEGLKNIDNEEI
                     FIEFTTNVNPCIIKPTDDVNYIYLLLPVRISSNI"
     gene            complement(9480..10799)
                     /gene="dnaA"
                     /locus_tag="JAM15_08270"
     CDS             complement(9480..10799)
                     /gene="dnaA"
                     /locus_tag="JAM15_08270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HAT6798244.1"
                     /translation="MDIVSLWDKTLQLIKGDLTSVSFNTFFKNIVPLKIHLNDLILLA
                     PSDFNKDILENRYLHLIEDAISQLSLKKYNIKFVLSEKEVADLNSDSTDLNYRVLYPN
                     LNPKYTFDTFVIGNSNRFAHAACVAVAESPAKAYNPLFLYGGVGLGKTHLMHAIGHHI
                     VSQKKDSKVVYVSSEKFTNELINSIKDDKNEEFRNKYRNVDVLLIDDIQFIAGKERTQ
                     EEFFHTFNTLHEANKQIIISSDRPPKDIPTLEDRLRSRFEMGLITDIQAPDFETRIAI
                     LRKKAQLERIDVPNEVMSYIAKNIKSNIRELEGALTRVVAYSSLSNRVISFDLATEAL
                     KDIITTSKNEEINVLRIKEKVSSVFNLKMEDFNSKKRTRSIAYPRQIAMYLTRELTDL
                     SLPKIGEEFGGRDHTTVIHAHDKVSKDIEESEEIKTKIDKIISDLKG"
     gene            11458..11595
                     /gene="rpmH"
                     /locus_tag="JAM15_08275"
     CDS             11458..11595
                     /gene="rpmH"
                     /locus_tag="JAM15_08275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HAT6798245.1"
                     /translation="MSKRTYQPKKRQRSKEHGFRKRMKTSNGRNVLKRRRAKGRNRLT
                     H"
     gene            11673..12017
                     /gene="rnpA"
                     /locus_tag="JAM15_08280"
     CDS             11673..12017
                     /gene="rnpA"
                     /locus_tag="JAM15_08280"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HAT6798246.1"
                     /translation="MDFNRTKGLKKDSDFRKVYKHGKSFANKYLVIYILKNKSDYSRV
                     GISVSKKVGKAITRNRVRRLIKEAYRLNIDEKIKPGYDIVFIARVSSKDATFKDIDKS
                     IKNLVKRTDISI"
     gene            12049..12300
                     /gene="yidD"
                     /locus_tag="JAM15_08285"
     CDS             12049..12300
                     /gene="yidD"
                     /locus_tag="JAM15_08285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HAT6798247.1"
                     /translation="MNKIIYILKEISKYLSNLCIYLVRFYQKYISPLKGPTCRFYPTC
                     SQYSIEAFKKYGFVKGMYLTIRRLLKCHPFHPGGYDPLK"
     gene            12332..13039
                     /locus_tag="JAM15_08290"
     CDS             12332..13039
                     /locus_tag="JAM15_08290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YidC/Oxa1 family membrane protein insertase"
                     /protein_id="HAT6798248.1"
                     /translation="MNIIGNFLGLILKVIFEFVNHYGISIILFTILVKIILLPLTIKQ
                     TKSTKAMQDIQPRIKEIQEKYKNKPEKQNEEIVKLYGEAKINPLSGCLPLLIQFPILI
                     GLFSVLREPVAHGVFANKAAFLAADNGFLWIKSLTSPDYVLAVFSGASAYVMQKVMTP
                     KDQLQGSMKVMTYVMAGMSFYWGFIFPAGLTLYWTVSNLFSIAQYYLIMNPLKAKLAA
                     NSKEEKVNEKKPKINKK"
     gene            13008..13637
                     /locus_tag="JAM15_08295"
     CDS             13008..13637
                     /locus_tag="JAM15_08295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HAT6798249.1"
                     /translation="MRKSLKLIKSKSKEEAISKAIAELNLKAEDIEVEILENPSKGFL
                     GFIGAKDGTYEIFVIEREVDVAKNFIEVMLKNANVDAKVNVSQKDNLIMVDIEGKEAA
                     SLIGRRGETLDSIQFLTGLALNKINKDSHTRVLVDIENYRSKREESLIRYANKVAREV
                     AKTRKTKKLDYMNPYERRIIHSALQNDKYVITYSEGTDPYRRLVIECKR"
     gene            13749..15128
                     /gene="mnmE"
                     /locus_tag="JAM15_08300"
     CDS             13749..15128
                     /gene="mnmE"
                     /locus_tag="JAM15_08300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HAT6798250.1"
                     /translation="MFIDDTIAAIATAPGEGGIGILRISGERALKVAEEIFKSMSGKS
                     IEEYNKRTLIYGNILDNENIIDEVLLAYMKGPNSYTGEDVIEINCHGGFISVKKILEL
                     ILSKDIRLAEAGEFTKRAFLNGRIDLSQAEAVIDVIKAKTDIAHEVAQNQLEGSLSKK
                     IRELRDKVTEILAHVEVAIDYPEEDIEHITYQTLKEKTDELKKEIKKLYDTAESGKIL
                     REGLKTVIVGKPNVGKSSLLNSILGENRAIVTDIPGTTRDVIEEFVNIKGIPLKIVDT
                     AGIRDTDDIVEKIGVEKSKESFTSADLIVMVLDASRKLSEEDIEILEKLKDKQTIVLL
                     NKNDLKQEIEEEKILKYVENNSIIKISALQQEGIEELQDKIESMVYKGSIKNNSSLVV
                     TNSRHKDALSKAYKSATDALIALEQSMPFDFVEVDLKNIWDYLGYINGDTVTEDLLDN
                     IFHNFCIGK"
     gene            15223..17118
                     /gene="mnmG"
                     /locus_tag="JAM15_08305"
     CDS             15223..17118
                     /gene="mnmG"
                     /locus_tag="JAM15_08305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HAT6798251.1"
                     /translation="MIKFEAGKYDVIVVGAGHAGCEAALATARMGYKTLIITMSLDSI
                     ALMPCNPSIGGTGKGQLVKEIDALGGQMGLNIDKTYIQSRMLNTAKGPAVHSLRAQAD
                     KFKYHEEMKKTLEDEPNLDIAMDEVVEILHEGNVVIGVGTKLGCSFKSKAVILATGVY
                     LNSKIYMGEVAFYEGPNALGYAKYLTDSLVELGLRMRRFKTGTPARVHRDSIDFSVMS
                     LQEGDEKVTPFSFMNENIEKKQEPCYLTRTTEETQKVILDNLKRSAMYSGVIESTGPR
                     YCPSIEDKVVRFSDKTSHQLFIEPEGLNTKEMYIQGISTSLPFEVQLDMYKTIKGLEN
                     CKIMRPAYAIEYDCVDPTQLKISLEIKGVENLFSAGQFNGTSGYEEAAAQGLMAGINA
                     VRKIEGKEPFVLDRSEAYIGVLLDDLVTKGTNEPYRMMTSRAEYRLYLRQDNADMRLT
                     QKGYDIGLVKKDRYERFLNKKAAVDKEFERLKNERVTPKEVNSLLEEKGATPIKVGIS
                     LYEFLKRPEVTYELLEELGKGAGEDVSREVKEQCVIITKYEGYIEKQLKQIDQFKKLE
                     NKKLDEKINYSSIEGLRLEARQKLDDIKPISIGQASRISGVSPADISVLLIYLEQVRR
                     TRGGKGE"
     gene            17111..17830
                     /gene="rsmG"
                     /locus_tag="JAM15_08310"
     CDS             17111..17830
                     /gene="rsmG"
                     /locus_tag="JAM15_08310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HAT6798252.1"
                     /translation="MNNIELLKNGIEGFNIDTNDSMLEKFKIYREILVEWNKKMNLTG
                     IEDEKEVYIKHFLDSISAVKNGYIKNGMSIIDVGTGAGFPGIPLKICLDSLELTLLDS
                     LNKRINFLEEVSRVLELDNITFIHGRAEDFGKNEDYREKYDVATARAVAGLPILMEFC
                     VPFVKVGGYFICLKGPNANLELEESQKAIDVLGLEYIEKIDVELPEVDLNHNILVFKK
                     VMETPVKYPRKAGKPAKNPIK"
     gene            18005..18790
                     /gene="noc"
                     /locus_tag="JAM15_08315"
     CDS             18005..18790
                     /gene="noc"
                     /locus_tag="JAM15_08315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid occlusion protein"
                     /protein_id="HAT6798253.1"
                     /translation="MEDKRVMEIPIEDVVPNPYQPRKIFSQVSLEELSNSIKVYGIIQ
                     PITVRAKDGKYELIAGERRLRAAKLAELKTIPAIINNMNDESSAVLALLENLQREDLN
                     FIEEAIGYENLIKEHAFTQQQLAEKLGKNQSTVANKLRILKLPNDIKMKLIENNLTER
                     HARAFLKLPSEDLMQSVLDKVIKNELTVKKTEKLIQDVLEETKVQEEPDKKQNIKGAM
                     SIRIYINTIKQAFDAISNTGIDAKYNEIDKGDYMEVVVKIPKK"
     gene            18925..19698
                     /locus_tag="JAM15_08320"
     CDS             18925..19698
                     /locus_tag="JAM15_08320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAT6798254.1"
                     /translation="MGKVIAVFNQKGGVGKTTTNVNLSASLGTLGKKILVLDLDPQGN
                     TTSGYGINKNEVENTIYEIMLDGLHIKEAIISTEFENVDVVPSATELSGAEIELTSKT
                     NREYILKNSIKAVIDEYDYIFLDCPPSLGMLTINCLTAVDSVLIPIQCEYYALEGVSQ
                     LMETIKLVKSRLNADIEIQGVVLSMFDGRANLSIQVVEEVKKYFKGSVYTTLIPRNVR
                     LAEAPSHGKPVIYYDKRCRGSVAYLELAEEFIDLEEEEW"
     gene            19700..20563
                     /locus_tag="JAM15_08325"
     CDS             19700..20563
                     /locus_tag="JAM15_08325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HAT6798255.1"
                     /translation="MENKSKRSNRLGRGLSALIPEIKGETSEKEIVNIDIDKIYPNEV
                     QPRKQFDEEKIKVLSDSIKNYGVLQPIVVKMDENNKYMIIAGERRFRASKLANKNQIP
                     AIIKDIDMKDIMEIALIENLQREDLNSIEEALAYKSLIEHYNVTQEEISEAVGKSRPH
                     ITNTLRLLNLGQDVIEMIDSGRITAGHGKALLRIADKDLQLQIAKKIEEEELSVREVE
                     NIAKKISENKQEEPKKSKPKDVFILDVEDKLRNIFGTKVNISKGKKKGKIEIEYYNDD
                     DLNSIVSMLLE"
     gene            20596..21738
                     /locus_tag="JAM15_08330"
     CDS             20596..21738
                     /locus_tag="JAM15_08330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HAT6798256.1"
                     /translation="MIYLDNAATTYPKPERVYNAVLDCMKNYCANPGRAGHKLAMRAA
                     REIYDTRENIAKLFNVSNPMNIVFTSNATDSLNLAIKGVLQEGDHVITTSMEHNSVIR
                     PIKALEKRGIENTVVKCDYEGFLDYEDLEKSIKSNTKLIVTTHASNVCGTLIDIKKVG
                     EIAKKHNILFLVDASQTAGVYDIDVNECNIDMLAMPGHKCLFGPQGTGILYVREGLNL
                     NILKEGGTGSKSEEIVQPELFPDKYESGTHNTPGIAGLNQGILFIFERGINNIRQHEE
                     ELCQYMIDKLEEVPDIKIYGPKDSKKRASVIALNIGDMDSGEVTFLLDSDYNIATRSG
                     IHCSPLAHTTLGTLKQGAVRFSIGYFNTKDEIDKAVEALKKISKNK"
     gene            complement(21873..22448)
                     /locus_tag="JAM15_08335"
     CDS             complement(21873..22448)
                     /locus_tag="JAM15_08335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerMN domain-containing protein"
                     /protein_id="HAT6798257.1"
                     /translation="MKNKKIMLVLSILSISIFAVGCTNAQNGSDTSKKETKSNTNVEQ
                     PKEENNTEKEVPNNKAKPTPKEETKTQSTTIYSFDVDKTDLIENKVDLNKIDENTLFE
                     ELQKLKVVPESAKLNSFTTKDIDGVKTGILDVSSDFTKSNLGSDAETLMLDSVARTYI
                     KNMNVEQIKITVDGSNYESGHIVLEEGDYLK"
     gene            22708..24000
                     /locus_tag="JAM15_08340"
     CDS             22708..24000
                     /locus_tag="JAM15_08340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAT6798258.1"
                     /translation="MEILSLGEKIKKLRKEKNMTLKELAGDRITAAQISHIERDKSHT
                     SYELLEYLGDKLDVSVEYLLETKEMQSKKITDNLILQSEIYIKENELNKAEDQIKEVL
                     DICKRYDLMENYGRCNFLMANINLKKSNYNDAIENFEKALYFFIKNSDSENILKCYLN
                     IGKIYMQEDFYKGAISHFNFAEEILSENKFEDVNIHKELYSKMAYCYIKLDNPNMSLK
                     YIEKINEIDNRNDRKEDVDILVLKANNMLEIGKYEESRDYFKKALKILESEDNKTGLA
                     NVYLTICDVYRKIGETDRVLEYSQKVYDIKKNDEDEYMMSGLFKIIEAYIDKEDYDLA
                     RKYCKIALASSIKNKNKFNEYKALRFYANMYKNQNEVTLAIEYLIKCIKIVSDLGNNR
                     ILANLYIDLGQLYSNISKEKELEYYQKGVFMYKNLEIM"
     gene            24105..24707
                     /gene="yedF"
                     /locus_tag="JAM15_08345"
     CDS             24105..24707
                     /gene="yedF"
                     /locus_tag="JAM15_08345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase-like selenium metabolism
                     protein YedF"
                     /protein_id="HAT6798259.1"
                     /translation="MSIKIDARGLACPKPVINTKRELDNLEEGVVVTIVDNETAKENI
                     LKLAKSLSCEANIVDEKENFISIEIRKGKNILDKQNVVDNKESELDNTCIFISSDKMG
                     LGNDELGKVLIKGFIYTLTESKPYPKYVLLVNGGVKLSAENEETIENLKILENMGVEV
                     LSCGTCLDYYNLKDKLQVGTVTNMYTIVETLKNASNTISI"
     gene            24780..25043
                     /locus_tag="JAM15_08350"
     CDS             24780..25043
                     /locus_tag="JAM15_08350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3343 domain-containing protein"
                     /protein_id="HAT6798260.1"
                     /translation="MNQMYIVSFNSTHHAIRSEKLFGENSLKVMALPTPREITASCGI
                     SIKFSFEDMEKIKTILVENNVDIKGIYCISKLENGSKEVEKLD"
     gene            25058..25243
                     /locus_tag="JAM15_08355"
     CDS             25058..25243
                     /locus_tag="JAM15_08355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HAT6798261.1"
                     /translation="MPMDLKIGDIVELKKQHACGCKEFEIIRTGMDIKIKCTKCSRLI
                     MLDRETLEKRVKKLIKK"
     gene            25346..26542
                     /locus_tag="JAM15_08360"
     CDS             25346..26542
                     /locus_tag="JAM15_08360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAT6798262.1"
                     /translation="MAVKYAKRMQGLQGSEIRELLKLTQQPQIISFAGGMPAPELFPV
                     EEMKKVSVAVLEENGRSAMQYTTTEGYEPLREKIAARMNDKNKTNVNKDDILVTSGSQ
                     QGLDFAGKVFIDEGDVILCESPSYIGAINAFKSYQPKFIDVPTDSDGMIMEELEKILE
                     TTDRIKMIYVIPDFQNPTGRTWPLERRKKFMEIVNKFEIPVIEDNPYGDLRFEGETLP
                     SLKSMDTKGLVIFLGTFSKIFCPGYRLGWTCASPEILSKFNFAKQGADLQASTISQME
                     VSKFMDMYDLDAHVDKIKAVYVKRRDVMLKTMEEEFPEGLVFTHPEGGLFTWVELPSN
                     LNAKELMPKCLEKNVAYVAGGGFFPNGGRENTFRLNYSNMPEEKIIEGIKNIAAVLKE
                     AMGVEA"
     gene            26756..27034
                     /locus_tag="JAM15_08365"
     CDS             26756..27034
                     /locus_tag="JAM15_08365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HAT6798263.1"
                     /translation="MRNYELVYVVKPNSDEEVREAILNKVKEVVATDGEIVKVDTWGT
                     KKLAYPIAKFTEGFYVLVNFKSAVDVPKEIDRNLKINENVIRHMIVVA"
     gene            27071..27505
                     /gene="ssb"
                     /locus_tag="JAM15_08370"
     CDS             27071..27505
                     /gene="ssb"
                     /locus_tag="JAM15_08370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAT6798264.1"
                     /translation="MNQVVLVGRLTRDPELRYIPGTGTPVASFTIAIDRDYVKKDGSK
                     ETDFIPVEVMGKSAEFCANYITKGRLVALQGSIRVDNYQTQSGEKRTFTKVSTRSVQA
                     LDSKNKSENSYRESAPAFEPSFEPQGLDPQGFQAIDDDDIPF"
     gene            27524..27751
                     /gene="rpsR"
                     /locus_tag="JAM15_08375"
     CDS             27524..27751
                     /gene="rpsR"
                     /locus_tag="JAM15_08375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HAT6798265.1"
                     /translation="MMNKKRRKKKRVCQFCADKNAKIDYKSTQRLQKYITERGKILPR
                     RISGTCAKHQRELTVAIKRARNIALLPYTLD"
     gene            27894..28214
                     /locus_tag="JAM15_08380"
     CDS             27894..28214
                     /locus_tag="JAM15_08380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798266.1"
                     /translation="MKIDKGSEITRNIKIIEWMKTEILMSVSDLFNLLFKGVKPLDEA
                     IQDTLANIIMITYLLAKRLGISFRDVDYKVKEKIKIGIDEDHSVERWYGDLSNLKKHM
                     DNRE"
     gene            28222..29178
                     /locus_tag="JAM15_08385"
     CDS             28222..29178
                     /locus_tag="JAM15_08385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YybS family protein"
                     /protein_id="HAT6798267.1"
                     /translation="MNNKIRLSKAMSIIVLAIIIALVIAYIPMLGIFSMLAAVPYVII
                     GAITDRKYSLISILVTFCVLILFADISYALNICIMYSLPGIVIGKMLKRSFEQEDSNK
                     FEPIYGGTIIFVLSMLVYFFVLKTFLNVNLLDEVSKMISEIVNIQKNSFSATELKVFD
                     KMKPDEIVSYFTNMLPMMLFLQGLLSAFVTYYLSVFFIKRITKMNIRFPKFADFYLPG
                     NAILTTFLLYLLVLFIQIIGSKLYTELIMTNLQLVFNLMFVIQGIAVCIYFLKKWIRQ
                     GPNKIMFFSGIILCLFGFMGISFVGMVDSIIDFRKVRSYKST"
     gene            29189..31183
                     /locus_tag="JAM15_08390"
     CDS             29189..31183
                     /locus_tag="JAM15_08390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoesterase"
                     /protein_id="HAT6798268.1"
                     /translation="MSNKQTFKLNMPEINLYIIVIGISSIILLYYNLYVGCLFFCIFV
                     YMVFHNWRTTNIRRHEWTEYIQNLSLDIDETTKKAIINLPIPLCILEFDGNISWYNGK
                     FYDMIGQKDLLDKNIEDIVKNLNLRKVLNENKEMYTEINYKEKEYTIIYNVIKNDQEK
                     NPKYLMILYWIDKTEYLKVKQNYDDEKNAMMLIQVDGYDEVLKSAAEDKRALINVEVE
                     KILSALELNSNGALRRTSKDKFFLVMHKKELKKLEAEKFSILDTIRHIDYGNNLPVTI
                     SIGIGIDGDTLNENLKLATGALDLALGRGGDQAVVKTKDKFVFYGGKSKAVEKKTKVK
                     SRLIGHALREVIQQSDQVYIMGHKYPDMDAMGAAVGVYDICKSCNKTANIVLQSVNES
                     IEIFINKINENNYYKKLFIGKEEAIDNCTKNTLVVVVDTHRPNYTECEELLKLSEKVV
                     VIDHHRRGVEFINDAVLLFHEIYVSSTCEMVTELVQYMDEDVTINKLTAEGLLAGISL
                     DTKNFAFKTGVRTFEAASYLRKVGADTIEVKKFFNSDVKDFIIKAEIIQSTKIINNRI
                     CLAYSSTEIDSINVIIAQTADELLNIKEVEASFVLGEKDDTIFISARSLGQINVHVLM
                     EKLGGGGHIDIAGAQLKNVSLKEAYKMVNKIIEEYLEEEE"
     gene            31184..31633
                     /locus_tag="JAM15_08395"
     CDS             31184..31633
                     /locus_tag="JAM15_08395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HAT6798269.1"
                     /translation="MKVILLKDVKGTGKKGEMKEVSDGYARNFLFPKKMAVQADSVAI
                     KELNEKNKSKEIKAQKEYEEAVLLGKQMEEINIEIYSKAGEGGRLFGSITSKEIAEQL
                     KKQKDIDVDKRKILLDEPIRSLGSTFVEIKIHQKVTTKIRVDVKEKQ"
     gene            31652..32980
                     /gene="dnaB"
                     /locus_tag="JAM15_08400"
     CDS             31652..32980
                     /gene="dnaB"
                     /locus_tag="JAM15_08400"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HAT6798270.1"
                     /translation="MEDMTRIPPHSVESEQSILGSILLDKDAIITVTETIKPDDFYKE
                     AHKIIYECMITLSNKGEPIDLITLTEELRKQGHLNDIGGISYITSLSTIVPTTSNVKY
                     YADIVKEKSVLRKLIKASNEIINLGYSGATKIEDVLEQAEKSIFDISQEKTSDDFKSI
                     NLVLMDAYDMIEKLYTNKSDVTGITTGFKDLNKKINGLQRTDLILIAARPAMGKTAFS
                     LNLVQNAALKGDASVAVFSLEMSKEQLVQRMLSSQSSVELKKIKTGTLNDNDWPRIID
                     AMAVLSDAKIHIDDTPGIKISELRSKCRKLKIEKGLDLVLIDYLQLMEGEGNNESRQQ
                     EISKISRSLKILAKELNCPVVALSQLSRAPEQRADHRPMLSDLRESGAIEQDADIVMF
                     LYRDEYYHADSESKNIGEVIIAKNRHGETGSVELVWLGEVQRFGDKLRDL"
     gene            33185..33493
                     /locus_tag="JAM15_08405"
     CDS             33185..33493
                     /locus_tag="JAM15_08405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798271.1"
                     /translation="MEKISLKYIYPNIIKVLDEINLFRVIDNNLRESIVVYANNVDNQ
                     YHINMTNTNFGNIINICKLEKLSDVDKFMEKVIKYEKEIIEKEEFSKIEEYMLNIGEY
                     "
     gene            33575..34864
                     /locus_tag="JAM15_08410"
     CDS             33575..34864
                     /locus_tag="JAM15_08410"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HAT6798272.1"
                     /translation="MKTVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLV
                     VEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFLEELEMFKTDNISTENIKISDRA
                     HVIFPYHKELDALSEEARGDLKIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAIKL
                     KAQIDAKNEIVKNIYGKEELFDFETIYNEYLGYAEQIRKYVADTSVIVYDAVRAGKKV
                     LFEGAQGTLLDLDLGTYPFVTSSHPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEG
                     PFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYAARVNGLTSISFMLLDV
                     LTGFDKIKVCTSYKMGDKIITDFPASLDDLAKCEPVYEELDGWNEDITQIDNFDDLPE
                     NAKKYVAKIEELVGVSVDMVSVGPNRAQTIIRRNIFA"
     gene            35189..35264
                     /locus_tag="JAM15_08415"
     tRNA            35189..35264
                     /locus_tag="JAM15_08415"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35222..35224,aa:Lys,seq:ttt)
     gene            35271..35345
                     /locus_tag="JAM15_08420"
     tRNA            35271..35345
                     /locus_tag="JAM15_08420"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35304..35306,aa:Glu,seq:ttc)
     gene            35350..35425
                     /locus_tag="JAM15_08425"
     tRNA            35350..35425
                     /locus_tag="JAM15_08425"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35383..35385,aa:Val,seq:tac)
     gene            35459..35533
                     /locus_tag="JAM15_08430"
     tRNA            35459..35533
                     /locus_tag="JAM15_08430"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35491..35493,aa:Thr,seq:tgt)
     gene            complement(35916..36908)
                     /locus_tag="JAM15_08435"
     CDS             complement(35916..36908)
                     /locus_tag="JAM15_08435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAT6798273.1"
                     /translation="MNEDKIRKILAKYAKRRDDNELLLEHRKNEVYNRIPEIKSIDDE
                     ISKIGLSLAKIVLLNPKSKDEIVKKTKENIESLKVKKEKLLSESNIPLDYLEIKFQCI
                     SCKDKGFLPNGEKCSCLKQEIVNEAYKMSNLDRILSQENFSNFNLNIFSPKKGSDGEI
                     SPRENMLNNLSICENFVHDFKKDNSENLLFYGSTGLGKTYMCNCIAKELLDKGNVVIY
                     QTSFRILDILEDYKFRRDTNNQISEDNYKNLFDCDLLIIDDLGTELNNSFTSGEIFNI
                     VNTRLVAGKKIIISTNLTPSQIGNTYTQRTLSRILDKFRILEFTGDDLRWERFK"
     gene            complement(36917..37975)
                     /locus_tag="JAM15_08440"
     CDS             complement(36917..37975)
                     /locus_tag="JAM15_08440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HAT6798274.1"
                     /translation="MFFKESNEIDLGEITIPNIFIDIFMPMADGLYVKVYLLGYRQAC
                     DITSNPKFDNNSIAKNLNIPLSDVLSAWKFWEEKKIIKIHDNGEYDNFNYSIEFLDLK
                     NFYIENILSNNSSIKSNTDKVVSTSENPSIRKMFNSINKIVGRYLDPSEKMSIMDIMN
                     KYNMSPDMILCAYEYVKDKTGTSKPVKYIEGIIRNWYDSNLYTPKDVEESFLVRSERY
                     ILYKTIFNELGFSRQPSKSEKELMDTWFDKFNMDIDLIINACSKSKNISNPSISYING
                     IIKNWNEKNIKNLNDLKQKEEERIVKENINKKQINTTQNNNTYKKTKFHNFNETFTQY
                     TSDELDEIIKKSQKEKFK"
     gene            38100..39563
                     /locus_tag="JAM15_08445"
     CDS             38100..39563
                     /locus_tag="JAM15_08445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HAT6798275.1"
                     /translation="MVIKFNQKVRRTLSVAILFMVLIIGCFIEKDDSLETYKEKTNSK
                     INQYNMDVIFDDETKRLMCNQNVDYINNTKSNIDKIYFHIYPNAFSKKDFAPFEKSEM
                     TRAYPNGFNEGYIDIKNILNNNSKMEYKIKGDKNDILEIELGKELKPNERMSLDIKYN
                     VKIPNSIGRFGYGENTINVTNWFPIACVNDERGWNLKSYETIGDPFYSETSDFHVKLL
                     IPNKYKIAHTGKLIDDKHDNKKMLYEIEAENVRDFAFILSSKFDVNKVDSKGVAINTY
                     NLNKKLSKKATEVAKDSINIFSELFGKYPYKEFSVVASDFFIGGMEYPMLVMIDQSLY
                     NEKNEFLLEYVIAHETAHQWWYSAVGNDEISEPWLDEALTEYSTIVYFEQKYGKDMAN
                     KLIKTMEIQTKSYLSENIFKPANEYKNSTEYSLNVYTKGAIAFNEIRKEVGDKVFFET
                     LNEYYNKYKHKNANGRAFVELWNSKGVDINKIISECK"
     gene            39665..40462
                     /locus_tag="JAM15_08450"
     CDS             39665..40462
                     /locus_tag="JAM15_08450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAT6798276.1"
                     /translation="MLKYCSVGSGSSGNCHYIGYKNTNILVDAGLSGKRITTGLKDIG
                     VDADKLKGIFITHEHVDHIKGAGILSRKFDIPVFANIKTWCSMKDKLGDIKDKNMKVF
                     ENDKTYSLGDIIVRPFSIEHDASDPVGYNFYTESDEKMSIATDIGCITQNIKKHLYKS
                     KLVVLESNYDPNMLMMGSYTYALKKRVMSSTGHLSNEDAANFCVELINEGTESILLAH
                     LSKENNFPELAYETSKGVLASNDIVVGQDVKLDVLSRNDVSNVYEMK"
     gene            40475..42577
                     /locus_tag="JAM15_08455"
     CDS             40475..42577
                     /locus_tag="JAM15_08455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC/EAL
                     domain-containing protein"
                     /protein_id="HAT6798277.1"
                     /translation="MLKRNFENVEDNKILYSIKQGMILAIPAIMTGSTALVILNLPIK
                     AYQEYLSGLFNGEVTNILNFINDSTLGIISLIILLTISYSYGKIYGSKYTVLVPIVAM
                     CSFLVFSHGNELNSYIEIFKTKWLFTSIIVSMTSSVLFVKLTESFVTSVKFHTEGADA
                     DFNMVVSAIVPFIIVVFLFSIFRVIMISLIGSSNFQDIFYNLFSNVFNKMGTNLMSAL
                     LFIFLMHFMWFFGIHGSNVLDTVAKNLFENSMAININLVNNNQLPTEIFTKTFFDTMV
                     LLGGCGSLLCLVIAIFLSEKRINVRKLAKIASIPALFNINEMLVFGIPIVFNYIMFVP
                     FVITPIILTITSYVAMSTGIVPCTVSAVEWTSPIFLSGYMSTGSIRGSLLQVFNLCVG
                     VMIYIPFIKMSQNRYTYMFKNNIENLTNLLKRYELTGEQPNLLNHNGKISSISKMLAS
                     DLKFAMKRGEIELFYQPQVNYNGNVVGAEGLLRWKHSIGGFIYPPLVIILAKEEGFLD
                     ELGEYIINKACIDLKKSEKLLRNPVKFSVNISPDQLDDPKLPEQIKNIISSNDINPNM
                     LGIEITEQIALSGSQIIIERINAIHNLGIKLIMDDFGMGHSSLIYLQNNNFDIVKLDG
                     SLVKEILTNKRSSEIIMTIVNLSKNLDFDIVVEYVENIDQRDKLYGLGCEIYQGYYYS
                     KAIPFEEFVEYANQEREI"
     gene            42645..43124
                     /gene="rlmH"
                     /locus_tag="JAM15_08460"
     CDS             42645..43124
                     /gene="rlmH"
                     /locus_tag="JAM15_08460"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HAT6798278.1"
                     /translation="MNISIVVVGKIKEKYLKLGIDEFKKRLSKYCKLEIIELDDEKAP
                     ENLSVKEMEIIKDKEGKKILGKIKHNSYVIALAIDGKGLSSEELAKTMSDLAVRGNSS
                     LCFIIGGSLGLSDEVLGRADYRLSFSKMTFPHQMMRLILLEQIYRAYRINNGEPYHK"
     gene            43273..43584
                     /locus_tag="JAM15_08465"
     CDS             43273..43584
                     /locus_tag="JAM15_08465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAT6798279.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMESAAKENGIESQIWAIPESTIQN
                     EIEKCDVLLLGPQVRYVLPKAQEIAKPYNIPVEVINMMHYGTVNGEAVLNRAIELNNT
                     K"
     gene            43632..43949
                     /locus_tag="JAM15_08470"
     CDS             43632..43949
                     /locus_tag="JAM15_08470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAT6798280.1"
                     /translation="MDEKIIEISFNIIGYAGEGKGLAFEAIKEAKNGNIEKAKELLKE
                     SKEVINKAHRYQTELIQNEASGNRTEISVILIHAQDHLMNGMNFQQLAEEIVDLHLKL
                     QDK"
BASE COUNT        16607 a         5549 c         7013 g        14888 t
ORIGIN      
        1 ctcagatact attgttatca aaatatctgg ctttatggtt tgtttcttaa tataaattaa
       61 cctactgttt aattttcaat gttcgtgttt atttcttgtt ccttttttca aggacaagta
      121 atactatacc atctttaaaa cagtaggtca atactttttt tatatttttt tataaatttt
      181 tttcatattc ttttttcagc ttctctacta cctttttctc tagtctagaa acagtcatct
      241 gtgatatccc tagttcttta gctatactag attgtgtttt atcaaagaaa aatctatctt
      301 taaaaatttt aacttctaat tcatttaaag tttcaataaa cttattaata aaatcttcat
      361 actctatact tccaaagtta ccttcttctt ttccaatctt atcaataaga gttatatctt
      421 tatcctctga atcatcatta cttgatgaat ccaaagacat tggttgatat ccataagaag
      481 cctccatagc ctctaaaaca tcttcttcac taacgcctat ataatcagct atatctttta
      541 cctttggatg cttcttattt tcttgttcta atttaatctt cgcatcactt atctttttgc
      601 ttaattcctg tattcttctt gggactctaa gtgtccatac cttatctcta aaatactttt
      661 ttatttctcc tactatagtt ggtgtcgcaa agctggagaa ctcaaatcct ttctcaacat
      721 catatctatc aatagcataa attaatgcca atgaagcaac ttgatatata tcttcaaaat
      781 caacaccttt gtttatatac ttcttagcta acaatcttgc taaatacaga tgtctttcaa
      841 taagaatatt tctaatgtct acatttttat ttttattata taaattaaat agctcttttg
      901 tatccatatt taggtaatgt gtagcattag ctacattttt cattaaatat caactcctaa
      961 atatttagtc atttttattt ttgtcccttg attatgttct gattcaatat ctacatcatc
     1021 cattaaagtt ttaattataa acaatccaag accactctct tttggattct ctaaatctgg
     1081 tgtacttatt gagctaacat catatccttt tccattatct tgaatttcta tattaattgc
     1141 attatctaaa atattaaata ctatattaaa cacatcatct ttactgtgtt ttattgcatt
     1201 tgtacatgct tcagatactg ctacctttat atcttctata tcatctattg gaaaacccat
     1261 cttattggca attccagatg ctgttaatct tattatacta acataatctg gatttgtagt
     1321 aatttccatc tttatagtct cacaagccaa agtttatccc tccactttaa atattttatc
     1381 tagacctgtt atagtaaaaa tcttttttac gttactctta ggatttacta tgtatatctc
     1441 tttttcattt atttttaatt tttttaatac acctatcata gctcctaagc ctgttgagtc
     1501 tatataatct aaatctttaa gattaatctt tacatctaac atattttttt ctattaaagc
     1561 atgtaaatgt tcctttagtt tatctgctgt agaaacatca agttctccat caagacaaac
     1621 attccaaaat ttattttgtg aatctaaatt tgaatcaata ttcatagaca tgtaaaaacc
     1681 tcctatttcc ttttaataat tttaaatata tttcctatac tcaatatttt attaattaca
     1741 taaactatat catctattcc ctttgatatt gatgatgcat tttcaacaat atcttgtata
     1801 tgtctttcat tataatctac aatcttatat gccttttcaa caaccttatt tatgctgttt
     1861 agagttttag ctaaataaat tgctactata agagcagagc ttcctactaa cactgctcca
     1921 atttgccacc cccatgcatt cattagttaa catctccctc atcatcaaag cttttactta
     1981 ttactatatc ttcttctgaa atctttatat cttcttcatt attatcatcg tccactaaat
     2041 ttattattct ctctttaaca tcattaaatg tttcatgtag aacttctttt ggattttctt
     2101 tgacatcatt aaacttctct tttgtttctt ttcttagttc agaacctttt ttaggtgcaa
     2161 aaaacatacc aaatataaac cctaaaatag ctcctaataa taaaaatcca ccttttttac
     2221 aacttctttt attgcacata acaattactc ctttcaattt taaattttta tctaactaca
     2281 ttatacaaaa agaataggat atttatccta ttcttcttca atatttattt tggcaatcga
     2341 aactacattg acttcatcat tcgtcttcat taatttaaca ccacttgtaa ctcttccaaa
     2401 cagtgatatt tcattgactc ttattctaat aagaactcca tcagaattta taatcattat
     2461 ctcatcatct tcgttgacca tatctgcacc tacaattgta ccagtttttt cagatatatt
     2521 ataagtttta attcctttac cagctcttat ttgacttcta tactcttcta tatttgttct
     2581 ctttccaaaa ccattcttac ttacaactaa cacatctgta cctttactgc aaaggttcat
     2641 agacacaaca aaatcttctt tacttaaagt tatacctttt acacccattg ctgttctacc
     2701 catatatctt atatcatttt catcaaatct tatagacata ccttctttag ttactaaaag
     2761 tacttcttgt tttccatctg taagttctac tccaataagc tcatcatcat ctcttaaacc
     2821 tatagcaata agaccagatt tatttatatt tttgaactct tctctcttag tctttttaac
     2881 aatacctttt ttcgttgcaa gtaataaata ttcattttca tcattaccat caataggtat
     2941 tagagtagca attttctcat ctgctgacaa ttgaagtaaa ttcactatag cagtaccttt
     3001 agcctgtctc ttaccttctg gtatttcata tgcatttaat ttaaatactc tacctttatt
     3061 tgtaaagaat aatagtctac tatgagtagt tgtagttacc aagtgcctta caaaatcttc
     3121 ttctctagtt gtaagtgctg aaatacctct tccacccctt ttttgactct tataagtatc
     3181 agatggaagc ctttttatat atccaaagtg agtaagagtt attgctattt cttcatcact
     3241 tataagatct ctcatatcta tttcgccttc agcatgtctt atttctgttc ttctctcatc
     3301 agagtaattt tcttttatta ttgtaatttc atcctttatt acatttaaaa gtaatctttc
     3361 atcagctaaa atttctttta atctatttat cttcttgatt aaatcttcat attcagcttc
     3421 tatcttatct ctttctaaac ctgtaagtct ttgaagtctc atatctaata tagcttgtgc
     3481 ttggatttca gttaatttga atttttctat taaacctatc ttagcttctt gcccagtctt
     3541 tgaagctctt atcaagctta taacagcatc tatattatct aaagcaatct ttaatccttc
     3601 taaaatatgt gctcttgctt cagctttatt tagttcaaat ttagttcttc ttgtaacaac
     3661 atcttcttga tgtttaatat aatgatataa tatttgttta agatttaaaa ctcttggctg
     3721 accatctaca agtgcaagca ttattatact aaaagtatct tccatttgag aatgtttata
     3781 caaattattt aatactatat tagcattagc atccctcttt aattctataa caattctcat
     3841 accatttcta ttactttcgt ctcttaggtc tgatatacct tctattctct tttctttaac
     3901 taactctgct attctttcaa ccagtttagc cttatttact tgataaggta tttctgtaac
     3961 tattatttgc tgttttcctt ttggtagttc ttctataaaa gctctagacc taactttaac
     4021 ttttcctctt ccagttctgt atgcttctgc tatactttct tttcccatta taattgcagc
     4081 tgtagggaaa tctggtcctt gaacaaattt tattaaatca tctacactac actctggatt
     4141 atctatcaaa tatacagttg catcaattac ttctgctaaa ttatgtggag gtattgaagt
     4201 tgccatacca acagctatac catttgagcc atttactaat aaattaggat atctagctgg
     4261 caatactgaa ggctctttta acgactcatc aaagtttggt ttaaagtcta cagtttcctt
     4321 ttcaatatct ctcagtagtt ctaatgataa tttactcatt ttagcttctg tataacgcat
     4381 agcagctggt gaatccccat caacagaacc aaagttacca tgaccatcta ctaaaagtgc
     4441 tctagttgaa aaatcttgtg ccattcttac catagcataa taaacagcag tatctccatg
     4501 aggatggtac ttacctaaaa cgtccccaac aatacgagct gacttcctgt atggtttatc
     4561 tggagttaaa tttaactcac tcattgaata taatattctt ctatgaactg gctttaaacc
     4621 atctctaaca tcaggaagag cacgtccagc tataacactc attgaataat caatatacga
     4681 ttttttcatt tcttccgcta tttcaatagg gagtattttg ttattttctt ccatgtatac
     4741 taatcccctc tctctatata tctaagtttc taacaaatct tgcattttct tctataaatt
     4801 cttttcttgg agcaacctta tcacccataa gcattgaaaa tacttcatct gcaattgcag
     4861 catcttctac agtaacttgt aataaagttc ttgtctcagg attcatagtt gtttcccata
     4921 attgctctgc attcatctct ccaagacctt tgtacctttg aagttcaaca ccatttcttc
     4981 caatttcatc taataagata tttaactctt tatctgagta aacataatgt tccttctttt
     5041 gctttgtcac tttatacaaa ggtggctgtg ctgcataaac atacccctca tctataagag
     5101 gtctcatata tctaaagaag aatgttaata ataaagttct tatatgggct ccatctacat
     5161 cagcatcggt cataattata attttatgat acctagcctt atctatatca aaatcttctc
     5221 caataccaca accataagct gttatcatat tttttatttc atctgaagat agtatcctat
     5281 ctagtcttga tttctcaaca ttaagtattt tccctcttaa tggaagtata gcttgactat
     5341 ttctatctct accttgttta gctgaacctc ccgctgaatc cccttcgact aagaatattt
     5401 cacttttaga tggatctttt tctgcacaat ctgcaagttt tccaggtaaa gatgtacttt
     5461 ctaatacact ttttctcctt gttaattctc ttgctttttt tgcagcttct ctagctcttt
     5521 gtgctcttaa agctttatca actatgattc ttgctgttga tgggttttct tctaggaaag
     5581 accccagttc atcaactgtt acactatcaa ctatacctct cataaagcta ttacctagct
     5641 ttgttttagt ttgaccttca aattgaggtt ctggtaattt aactgatact actgctgtaa
     5701 gaccttctct tatgtcttca ccaagtaggt taacatcatt ttcctttaaa aatttatttc
     5761 tcttagcata atcatttaca gttttagtaa gagctgcttt aaatccactt aaatgagaac
     5821 caccttcgtg tgtatttata ttgtttgcaa aagaatatat gttctctgta taaccatctg
     5881 tatattgcat agctagttca acaaaacaat catcaacctt tttatctata taaactatgt
     5941 catcatgtat accagttcta gatttattta aatacttaat atattctacc aaaccacctg
     6001 tatagtgaaa ttcttttctt ttttcttgtc cttctctttt atcttcaaat actattttta
     6061 ttcctttatt caagaaagaa agttctctaa gcctatactc caatgtttca tatttaaact
     6121 ctatttcatc aaatattgtc tcatctggca taaattgaat cattgttcct ttatcttgag
     6181 attctccaac tacttcaagc ttagatgttg gtaatccttt ctcatatgtc tgcttatata
     6241 tctttccgtt taaataaacc tctgctacca tccattttga caatgcatta actacagaaa
     6301 caccaactcc atgaagacct ccagatactt tatatcctcc gcctccaaac tttcctcctg
     6361 catgaagatt agttaatact gtttctaaag ttgatttacc agttttagga tgtatttcaa
     6421 caggtatacc tcttccgtta tcttttacta aaacactgcc atcttcatta atagatacat
     6481 atatgtctga acaatatcct tgtaaagcct catctatact attatctaca acttcataaa
     6541 ctaagtgatg taaacctcta gggcttgtac taccaatata catacctggt ctttttctaa
     6601 cggcttctaa tccctctaat acttgtatct gacttgcacc gtattcttgt ttcatttaat
     6661 ttcctccatt ctctatgcta ataacatcgc cattttcaat attaaatatt gtaacatttt
     6721 tttcatcaaa tattttttta tgtgaaactt cagcacttgt tataaacatt tgaacattgc
     6781 ttaaattatt tactaaaagt ttttgtcttg cttcatctaa ctcactaaaa acatcatcta
     6841 aaattaatac tggatattct tcaacttcat tttttattaa ttctatctct gataacttta
     6901 atgatattga agcagttctt tgttgacctt gtgaaccaaa aagtcttgca tctaaatcat
     6961 ttatgaatat atttaagtca tctttgtgta taccatatct ggtagtctta gattctatat
     7021 cattaggtct attcgatgac aacttggcta aaaatttatt atatactgta tctatagtat
     7081 cttcatcagt tatatttatt tgatttttat atcgaattga taatctttca actccattag
     7141 tcaaattcat atgcatattt tcagatatat tagctatctt ttttataaag tctctacgca
     7201 aaatataaat ataacttcca tactttgcta acgtatcatc atatacatct aataaagctt
     7261 catcaacatg tatattttta agcaccctac tcctttgaga aagtgtttta ttataattgg
     7321 taagatattt ataatattta ggtataatct gactaatctc tttgtctata aatgcccttc
     7381 tttctttagg accctcttta accaacctta aatcttcagg agaaaatata acaacattta
     7441 agttgccaag tagttcttgt atcttttgta aaggaacttt atttattctt atcccctttt
     7501 tatcttttcc aataattagc tctattagac tatatttatt atattttgaa aaacttcctc
     7561 caatatataa gttttcacta ttaaatctaa ccatttcttt atctttgtta gtcctaaatg
     7621 attttccaaa agaaagcata taaatagatt ctactatatt tgtctttcct tgaccatttt
     7681 taccaacaag tagatttact ttcccattaa attccagatg caacttttta taatttctaa
     7741 aattaacaag ttgcaaactt ttaagtttca caaaaagttc tccttttttt acaatacttt
     7801 tattttagtt ccttctattt taactatatc tcctgatttt atcttttttc ctcttcttaa
     7861 ttctatttca tcatttactg tcactaaacc ttcttgaatt aaaaattttg catgacctcc
     7921 tgttgatgca atctctgcta atttaagaaa ttgatccaac tttatatatt ctgattctat
     7981 agttatttca gtcataatag ttcctccttg tcactatttt aaacaaattc ctattgatac
     8041 actaaaagta tattatacca taaatatgct tataaaagga gttgtctaag attagaaaaa
     8101 ttttctacaa aagacaactc cttcatgtct gctatatatt tgatgatatt cttactggaa
     8161 gcagtaagta aatataatta acatcatctg ttggtttaat tatacaagga tttacatttg
     8221 tagtaaattc tataaatatt tcctcattat ctatattttt caaaccttcg ataaaatatc
     8281 tagaattgaa agctatatct aggtaatctc catctaaatc tatttcaact tcttcataca
     8341 catttccttt ttctgtgtta gaagtaattg ccattacttt atctcttata gataacttta
     8401 taagattatt tttttctgat tgagacaata aagacgctct ctctatacta tttaaaagtt
     8461 ccttagtgtt taatttaact ctgctgttat gttctcttgg caataatttt ttataatcaa
     8521 taaaatctcc ttcaagcaat cttgtaataa ttttcgtatc attaattata aaaatagcat
     8581 ttttttcgtt aaacccaact ttaacattat cctctccaga aagcaaacta tttacatcta
     8641 taagtgtctt tccaggaatt atgactttta tattttcagt taaactatca actgaacaac
     8701 tttttacagc taatctatat ccatcaattg ctactaaatt taagtttcta tctacaattt
     8761 ctaaaagttc tcccattaaa acaggttttg tttggtcctg tgagatagca aatacagttt
     8821 gtttaatcat attttttaga atttcttgag gtatgctata taaatcttct tcatttaatt
     8881 ctggtaattt aggaaattct tttgctgcat aacctttaat tttaaatctt gaatttacac
     8941 aatttatgta aatattattt tctgaatcag tttctatctc aacaaaggaa tctggtaatt
     9001 ttctaattat atctccaaat agccttgcat ctacaacaac atcacctttt tctatgattt
     9061 ctgcttgtac ataagtttct attcctattt cagcatcata tccagtaagt tttaattgac
     9121 cttcttctgt agatataagt atacctttta ataattctat tgttgttttt ccattaatag
     9181 ctttttgagc aattccaatt ctatttgcta ggattttttg attacaaatt attttcaatg
     9241 tggataacct cctctggctt tttatatata aaaataagtt aaaatcatag tagtaatagt
     9301 agtaggtgtt gttgataatg ttaataagta tgtataacat tataaataca aagatattaa
     9361 catgtgtata agatgttaat atctttgtta ttttagactt gataatttgt taataatttt
     9421 tgttcaaaaa aagtattaac aggttattca agagatataa acatacaatt gtgtataaat
     9481 tatcccttca aatctgatat aattttgtct attttagtct taatttcttc actttcttct
     9541 atatccttag atactttgtc atgagcatga attactgttg tatggtctct acccccaaac
     9601 tcttcaccta ttttaggaag ggataaatca gtaagctcgc gcgttaaata catagctatc
     9661 tgtcttggat aagctattga acgtgttctt tttttagaat taaaatcttc catctttaaa
     9721 ttgaatacag aagatacttt ttcttttatt ctaagaacat ttatttcttc atttttagaa
     9781 gttgttataa tatcttttaa agcttctgta gcaagatcaa aagatattac cctattgcta
     9841 agagaagaat aagcaaccac tctagttaat gcaccttcta gttcccttat gtttgactta
     9901 atattttttg ctatatatga cataacctca tttggcacat ctatacgttc tagttgagcc
     9961 ttttttctaa gtatagcaat tcttgtctca aagtcaggtg cttgaatatc agttataagt
    10021 cccatttcaa atctcgatct tagcctatct tctagtgtag gtatgtcttt tggcggtcta
    10081 tcactagata taattatttg tttgtttgct tcatgaagag tattgaatgt atggaaaaac
    10141 tcttcttgag ttctttcttt tcctgctata aattgaatat cgtcgattag taatacatct
    10201 acgtttctat atttattcct aaattcttcg tttttatcgt cttttataga gtttataagt
    10261 tcattagtaa atttttctga agaaacgtaa actacttttg agtctttttt ttgactaaca
    10321 atatgatgac ctatagcatg cattaggtga gtcttaccta atccaactcc tccatacaaa
    10381 aaaagtgggt tataagcttt agctggagat tctgcaactg caacgcatgc agcatgtgca
    10441 aatctattgc tattaccaat aacgaatgta tcaaatgtgt attttggatt tagattgggg
    10501 taaagaactc tataatttaa atctgtgcta tcagaattta aatcagcaac ctctttttcg
    10561 ctcaatacaa atttaatatt atattttttt aatgacagtt gactaatagc atcttcaatt
    10621 aaatgtaaat atctattctc taagatatct ttattaaaat cactaggagc cagtaagatt
    10681 aaatcattaa gatgtatttt taatggtacg atgtttttaa aaaaggtatt aaaacttact
    10741 gaagttaagt caccttttat taattgtagg gttttgtccc ataaagaaac tatatccata
    10801 atataaacct ccgaacagaa taattaatat tttccacaaa gttattaaca gaaaagcaaa
    10861 aatatatata aattttacag aataactaaa tttatggata atggtgttga taaattaata
    10921 atagtataaa ttattaaaaa aatatgaaaa gatataaaca atatgtagat aaagttataa
    10981 ataacataaa catacaataa atggtgatta taactagagt attgtcagta atcttaaaag
    11041 ttatacacaa aagtatccac aagctgtgaa taatttctaa taagttgata acatttatgc
    11101 acattatcaa caagtatatt tataatatca aaatatatgt caaacttcaa tgatttgtaa
    11161 ctaatttatc cacaatatta actaattgtt gataaaaata taaacatgtt aaaattactt
    11221 tatttgtgta tataattgaa aaaaataatt tagaataaaa ttaaatagat ttttgctagt
    11281 attttcaata aaaaaaatac ataatatata tatggtagat tttgtgatat aagcgtccca
    11341 aaaactcgtt gacaacagta gtaaaagtat ttataattat atgtgttatg tttactttga
    11401 gggtaaagtt attattttta taaacggaaa ataaaatctg aaaggcggtg caaaataatg
    11461 agtaaaagaa cttatcaacc aaaaaagaga caaagaagta aagaacatgg tttcagaaaa
    11521 agaatgaaga cgtctaacgg aagaaacgtg ttaaagagaa gaagagctaa aggaagaaat
    11581 agattaactc attaattaca aaagggccgc tgcaaaggtg gcctttttgt gtaaataatt
    11641 acaattcata gctgtgttta tggaggttaa ctatggactt taataggact aaagggttga
    11701 aaaaagactc tgattttaga aaagtatata aacacggcaa atcttttgca aacaaatatt
    11761 tagtaatata tatacttaaa aataaatcag attatagtag agtaggtatt tctgtttcaa
    11821 aaaaagtagg aaaagctatt actaggaata gagtaagaag attaataaaa gaagcctaca
    11881 gattaaatat tgatgaaaaa attaagcctg gatatgatat agtatttata gcaagggtat
    11941 ctagtaagga tgctactttt aaagacatag acaagtctat aaaaaattta gttaaaagaa
    12001 cggatatttc tatttaattg tatgctataa atatggaggt taatgacttt gaataaaata
    12061 atttatatat taaaggaaat aagtaagtat ttatcgaatt tatgtattta tttagtgaga
    12121 ttttatcaaa agtatatatc tcccttaaag ggacctacct gtagatttta tccaacttgc
    12181 tcacaatatt caatagaggc gtttaaaaaa tatggatttg taaaaggtat gtatttaacg
    12241 ataagaagac ttttaaaatg tcatcctttt catccaggag gttacgaccc tctaaaataa
    12301 aagagagtaa ctattaggag gtataaaaaa attgaatata ataggaaatt tcttaggatt
    12361 gattcttaag gtaatatttg aatttgttaa tcattatggt atttctataa tactttttac
    12421 gatacttgta aagattattt tattaccatt aacaattaag cagactaagt caacaaaggc
    12481 aatgcaagat atacaacctc gtataaaaga gatacaagaa aaatataaaa ataagccaga
    12541 aaaacaaaat gaagaaattg ttaagttata tggagaagct aaaattaatc cactatctgg
    12601 ttgtttacct ttattaatac agtttcctat attaatagga ttatttagcg ttttgagaga
    12661 accagttgct catggcgttt ttgcaaacaa agctgcattt ttagcagctg acaatgggtt
    12721 tttatggata aaaagcttaa catcaccaga ttatgtatta gcagtatttt caggagcaag
    12781 tgcatatgtc atgcaaaaag taatgacacc caaagatcag ttacaaggct ctatgaaagt
    12841 aatgacatat gtaatggcag gtatgtcttt ctattgggga tttatattcc cagcaggact
    12901 tacattgtac tggacagtaa gtaacttatt ctcaatagct caatattact taataatgaa
    12961 tcctttaaaa gctaaactgg ctgctaactc taaggaggaa aaagttaatg agaaaaagcc
    13021 taaaattaat aaaaagtaag agtaaagagg aagctataag taaagctata gcagagttga
    13081 atttaaaagc agaggatata gaagtagaaa tacttgaaaa tccaagtaaa gggtttttag
    13141 gttttatagg tgctaaagat ggtacttatg aaatttttgt tatcgagagg gaagtagatg
    13201 tagctaaaaa ttttatagag gtaatgttga aaaatgcaaa tgttgatgcc aaagtcaatg
    13261 tatctcaaaa agataattta atcatggttg atattgaagg caaagaagct gcaagtttaa
    13321 ttggtagaag aggggaaact ttagattcta ttcaattttt gactggatta gctcttaata
    13381 aaataaataa agattctcat acaagagtac ttgtagatat agaaaattat agatcaaaac
    13441 gagaagaatc tttaataaga tatgctaata aagttgctag agaagtagcg aaaacaagaa
    13501 aaactaaaaa attagattat atgaatccat atgagagaag aataatacat tcagctcttc
    13561 aaaatgacaa atatgtaatt acatatagtg aaggaaccga tccatataga agattagtaa
    13621 ttgagtgtaa aagataaagt caacctccta aacattaggg ggttttattt tttaatatta
    13681 ttaaatcatt aatgattggt taaatgtaaa cctatatgta aaaaattatg aattaagagg
    13741 tgataaattt gtttatagat gatacaattg cagcaatagc tacagcacct ggagaaggtg
    13801 gtataggtat acttagaata agtggagaaa gagctttgaa ggttgcagaa gaaatcttta
    13861 aatctatgtc gggaaagagt attgaagaat acaataagag aacattaata tatggaaata
    13921 tattggataa tgaaaatata attgatgaag ttttattggc atatatgaaa ggaccaaact
    13981 cctatacagg agaagatgtt atagaaatta attgtcatgg tggatttatt tcggtaaaga
    14041 agatattaga attaatacta tcaaaagata ttagattagc agaggctggt gagtttacta
    14101 aaagagcatt cttaaatgga agaatagatt tatctcaagc agaggctgta attgatgtta
    14161 taaaagccaa aactgatata gctcatgaag ttgctcaaaa tcaattagag ggttctttat
    14221 caaagaagat aagagaattg agagataaag tcactgagat attagctcat gtagaagttg
    14281 ctatagatta tcctgaggaa gatattgagc atataacata tcaaactctt aaagaaaaaa
    14341 ctgatgaact taaaaaagag attaaaaaat tatatgatac agctgaaagt ggaaaaatac
    14401 ttagagaagg cttaaagacg gtaattgttg ggaaaccaaa tgtaggtaaa tcttcactac
    14461 ttaattctat tttaggagag aatagagcaa tagttactga tataccagga actactagag
    14521 atgttataga agagtttgta aacataaaag gtataccttt aaaaattgtt gacacagcag
    14581 gtataaggga tactgatgat atcgttgaaa aaataggtgt tgaaaagtct aaagaatcat
    14641 ttactagtgc agatttgata gtaatggttt tagatgcatc tagaaagttg tcagaggaag
    14701 atatagaaat attagaaaaa cttaaggata aacaaacaat agtgctgtta aataagaatg
    14761 atttgaaaca agagattgaa gaagaaaaaa tacttaaata tgtagaaaat aatagtataa
    14821 taaaaatatc agctttacaa caagaaggaa tagaagaatt gcaagataaa atagagtcta
    14881 tggtatataa aggtagtatc aaaaataatt ctagtttagt agtaacaaat tcaagacata
    14941 aagatgcact tagtaaagca tataaatctg caacagatgc tttaattgct ttggaacaaa
    15001 gtatgccatt tgactttgta gaagtcgatt taaaaaatat atgggactat cttggatata
    15061 ttaatggtga tacagtaaca gaggatttac tagataatat attccataat ttctgtattg
    15121 gtaagtaatg tacaaaagta aatttgtttt tattatagag atttttaaaa aatttgaagt
    15181 gtttctcatg aaacattaat tttgaaaaga aaggaattat aaatgataaa gtttgaagca
    15241 ggaaaatatg atgttatagt agtcggagca ggacatgctg gatgtgaagc tgctttggct
    15301 actgcaagaa tgggatataa aactttgata ataacaatgt ctttggattc catagcatta
    15361 atgccttgta atccatcaat tggagggact ggtaaaggtc aattagttaa agaaatagat
    15421 gccttaggcg gtcagatggg attaaatata gacaagacat atatacaaag tagaatgtta
    15481 aatactgcca aaggtccagc ggtacactct ttaagagcac aagcagataa atttaaatat
    15541 catgaagaaa tgaaaaagac attagaagat gaaccaaatc ttgatatagc tatggatgaa
    15601 gttgtagaaa tacttcatga aggaaatgtt gtaataggag ttggaactaa actaggatgt
    15661 tcatttaaat ctaaagctgt aatattggcc actggagttt atctgaactc aaagatatat
    15721 atgggtgaag ttgcatttta tgaaggtcct aatgcattgg ggtatgcaaa atatcttaca
    15781 gatagcttag ttgagcttgg tcttagaatg agaagattta agacgggaac tccagcaaga
    15841 gttcatagag atagtataga cttctctgta atgtctttac aagagggcga tgaaaaagta
    15901 actccattct catttatgaa tgaaaatata gaaaaaaaac aagaaccttg ttatttaaca
    15961 agaactacag aagaaactca aaaagttata ctggataatt taaaaaggtc tgctatgtat
    16021 agtggagtaa tagaaagtac tggtccaaga tactgtcctt ctatagaaga taaagtagta
    16081 agatttagtg ataaaacctc acatcaatta tttatagaac cagaagggtt aaatactaaa
    16141 gaaatgtata tacaaggaat ttcaactagt ttaccttttg aagttcaatt agatatgtac
    16201 aaaactataa agggacttga aaattgtaag ataatgagac ctgcatatgc tattgaatat
    16261 gattgtgttg acccaactca actaaaaata agtttggaaa taaagggtgt cgagaactta
    16321 tttagtgcag ggcaatttaa tggaacttct ggatatgagg aagcagcagc tcaagggctt
    16381 atggctggta taaatgcagt tagaaagata gaaggaaaag agccgtttgt attagaccgt
    16441 tcagaagctt atataggtgt cttattagat gaccttgtta ctaaaggaac taacgagcct
    16501 tacagaatga tgacatcaag agcagaatat cgactatatt taagacaaga taatgcagat
    16561 atgagattaa ctcaaaaagg ttatgatata ggattagtta aaaaagatag atatgaaagg
    16621 ttcctaaata aaaaggctgc tgtagataaa gaatttgaaa gattaaaaaa tgaaagagtt
    16681 acaccaaaag aagtaaatag tttgttagaa gaaaaaggag caacaccaat aaaggttgga
    16741 atatctctat atgaattttt aaagagacca gaggttactt acgaattgct tgaagaatta
    16801 gggaagggcg ctggagaaga tgtttcaaga gaagttaaag aacagtgtgt aataataact
    16861 aaatatgaag gttatataga gaaacaattg aaacaaatag accaatttaa aaaacttgag
    16921 aataaaaagc tggatgagaa aataaattat tcatctatag aaggtcttag attagaggct
    16981 agacagaaat tagatgatat aaaacctatt tcaatagggc aagcatctcg tatatcgggt
    17041 gtttctccag ctgatatatc agttttactt atatacctag aacaagtcag aagaactaga
    17101 ggtggcaaag gtgaataata tagaacttct gaaaaacggg attgaaggtt ttaatataga
    17161 tacgaatgac agtatgttag aaaaatttaa aatctataga gagatattag ttgaatggaa
    17221 taaaaagatg aatcttactg gaatagaaga tgaaaaagaa gtgtatataa aacatttttt
    17281 agactctatt tcagctgtaa agaatggata tataaaaaat gggatgtcta taatagatgt
    17341 tggtacaggt gctggttttc ctggaatacc attgaaaata tgtttagata gcttagaact
    17401 tactttgtta gattcgttaa ataaaagaat aaacttttta gaggaagtta gtagagtact
    17461 agagttagat aatattacat ttatacatgg aagagctgaa gattttggta aaaatgaaga
    17521 ctatagagaa aaatatgatg ttgctacggc aagagctgtt gctggattac cgattcttat
    17581 ggaattttgt gtaccatttg taaaagttgg agggtatttt atttgcttaa aaggtccgaa
    17641 tgctaattta gagctagaag aatcacaaaa ggctattgat gttttaggat tggagtatat
    17701 tgaaaaaata gatgtagagt taccagaggt agatttgaat cataatatat tagtttttaa
    17761 aaaagtgatg gaaacaccag ttaagtaccc tagaaaagct ggtaaaccag ccaaaaatcc
    17821 tattaagtaa tgaaaaaagt aatgaaaaaa ttattattgg taagcttaat tatttcttag
    17881 gaaataatta agcttaccgt aaaaaaacaa aaataaagga attattaaag tagatgcaga
    17941 aataaatttg tatgtacata tagagaacaa aaataattta tatctaaaat aagagaggta
    18001 tgttatggaa gataaaagag ttatggagat acctatagaa gatgtagttc caaatccata
    18061 tcaaccaaga aaaatatttt cacaagtttc attggaggaa ttgagcaatt ctataaaggt
    18121 atatggtata attcaaccta taacagttag agcaaaagat ggcaaatatg aactaattgc
    18181 aggagaaaga agattaagag cagctaaatt agcagagctt aaaaccatac cagcaattat
    18241 aaataatatg aacgatgaat cttctgctgt tctagcgtta ttagaaaatt tgcaacgaga
    18301 agacttaaat ttcattgaag aagcaattgg ttatgaaaac ttaataaaag aacatgcttt
    18361 tactcaacag caattagcag aaaaattggg caaaaatcaa tctactgtag caaataagct
    18421 tagaatatta aagcttccaa acgatataaa aatgaagcta atagagaata atttaacaga
    18481 aagacatgct agagcatttc ttaaactacc aagtgaagat ttaatgcaaa gtgtgttaga
    18541 caaagtcata aaaaatgaat tgactgttaa aaaaacagaa aaattgatac aagatgtatt
    18601 agaagaaact aaagttcaag aagagcctga taaaaaacag aatataaagg gtgctatgag
    18661 tataagaatt tacataaata ctataaagca ggcctttgat gctatatcaa atacaggaat
    18721 tgatgctaag tataatgaaa tagataaggg agattatatg gaagttgttg taaaaatccc
    18781 taaaaaatag agattactgc ttaccagtaa tctttttttg taatataagc cttgtaatat
    18841 aaattgattt atagacatta tttatactta aaaaacacct attcaacatt taaaattaat
    18901 ttaattctta aaggggggaa catcatgggc aaagttatag ctgtattcaa tcaaaagggt
    18961 ggagtcggga aaactacaac aaatgtaaat ttaagtgcta gcttaggaac tttgggaaag
    19021 aaaatattag tattagattt agacccacaa ggaaatacaa ctagtggata tggtattaat
    19081 aaaaacgaag tagaaaatac aatctatgaa attatgttag atgggttaca tattaaagaa
    19141 gcaataataa gtactgaatt tgagaatgta gatgtagttc catcagctac tgaactatca
    19201 ggtgcagaga tagagcttac atctaaaact aatagagagt atattttaaa aaattccata
    19261 aaagcggtaa tagatgaata tgattatata tttttagatt gtccaccctc actggggatg
    19321 cttacaataa attgtttaac tgctgtagat agtgttttaa ttccaataca atgtgaatat
    19381 tatgctttag aaggtgttag tcaattaatg gagactataa aattagtaaa atcaagatta
    19441 aatgctgata tagaaattca aggtgttgtt ttaagtatgt ttgatggaag agctaattta
    19501 tcaatacaag tagttgaaga agttaagaaa tactttaaag gtagtgtata tacaacttta
    19561 attccaagaa atgtaagact tgcagaagct ccaagtcatg gaaaacctgt aatttattat
    19621 gataaaagat gtagagggtc tgtagcttat ttggagctag cagaagaatt tatagattta
    19681 gaagaggagg aatggtagta tggagaataa gtctaaaaga agtaatagat taggtagagg
    19741 tcttagtgca ttgataccag aaattaaagg agaaacttca gaaaaagaaa tagtcaacat
    19801 agatatagac aaaatatatc caaacgaagt tcaacctaga aagcaatttg atgaagaaaa
    19861 gataaaagta ttgtcggact ctataaaaaa ttatggtgtt ttacagccaa tagtggttaa
    19921 aatggatgaa aataataaat atatgataat agctggagaa agaagattta gagcatcaaa
    19981 acttgcaaat aaaaatcaaa tacctgctat aattaaagat atagatatga aagatataat
    20041 ggagatagcc ttaattgaaa acttacagag ggaagattta aattcaatag aagaggctct
    20101 agcatataag agtttaatag agcattacaa tgtaactcag gaagaaatat cagaagctgt
    20161 tgggaagagt agacctcata taactaatac actaagactt ttaaatcttg gacaagatgt
    20221 tatagaaatg atagacagtg gtagaattac agcaggccat ggtaaggctt tattgagaat
    20281 tgcagataaa gatttgcaac ttcaaatagc gaaaaagata gaagaagaag aactttctgt
    20341 aagagaagtc gaaaatatag ctaaaaaaat atctgaaaat aaacaagaag aacctaaaaa
    20401 atctaaacct aaggatgtat ttattttaga tgttgaagat aaacttagaa atatatttgg
    20461 aacaaaggtg aatatttcta aaggaaagaa gaaaggtaaa atagagatag aatactataa
    20521 tgatgatgat ttaaatagta ttgtatcaat gcttcttgaa tagaacaaaa atataaaaca
    20581 gagaggaaga ttgttatgat ttatttagat aatgctgcaa ctacatatcc aaaaccagaa
    20641 agagtgtata atgctgtttt agattgtatg aaaaattatt gtgcaaatcc aggtagagca
    20701 ggccataaac ttgctatgag agctgctagg gagatatatg atacaagaga gaatatagct
    20761 aagttgttca atgtaagtaa tcctatgaat atagtattta catctaatgc aacagattct
    20821 ttaaatttag cgataaaagg tgtattacaa gaaggagacc atgtaataac aacgtctatg
    20881 gagcataatt cagtaataag acctataaaa gcattggaaa aaaggggtat tgaaaatact
    20941 gtagtaaaat gcgattatga gggattttta gattatgaag atttagaaaa atcaataaag
    21001 agtaatacta aactgattgt aacaacacac gcatctaatg tatgtggaac tttaatagat
    21061 ataaaaaaag ttggagaaat agctaaaaaa cataatatac tatttttagt agatgcatca
    21121 caaacagcag gtgtttatga tatagacgta aatgaatgta atatagatat gttggcaatg
    21181 ccaggtcata aatgcttatt tgggcctcaa ggaacaggta tattatatgt aagagaaggg
    21241 ttgaacttaa atatattaaa agaaggtgga acaggtagta aatcagaaga aatagttcaa
    21301 ccagagttat tcccagataa gtatgaatca ggaactcata atactccagg tatagcaggt
    21361 cttaaccaag gtatactatt tatatttgaa agaggaatca acaatataag acaacatgaa
    21421 gaagaattat gtcaatatat gatagacaaa ttagaggaag taccagatat aaagatatat
    21481 ggaccaaagg atagtaaaaa aagagcatca gtaatcgctc taaatatagg agatatggat
    21541 tctggagagg ttactttctt attagatagt gattataata tagcaactag atcaggaata
    21601 cattgttcac cactagcaca taccacttta ggtactttaa aacaaggtgc agtaaggttc
    21661 agtataggat atttcaacac aaaagatgag atagataaag cagtggaagc tttgaaaaaa
    21721 atttcaaaaa ataaatagca tgagatttaa taatatagaa ataaaaaaag gggatatttc
    21781 aaaataaaaa tttgaatcat ctcctttttt gtacaaaaaa gaaaaggggg ctcctaagaa
    21841 cctctaatct atttgataat tgtttcaaga aattacttta agtaatctcc ttcttcaaga
    21901 actatatgac cactttcgta attagaacca tcaacagtaa tttttatttg ttcaacattc
    21961 atatttttta tgtaagtacg agcaactgaa tcaagcatta aagtttctgc atcactacct
    22021 aagtttgact ttgtaaagtc agagctaaca tctaatatac cagtttttac accatcaatg
    22081 tcttttgtag taaatgaatt taattttgca gattctggaa caactttaag tttttgaagt
    22141 tcttcaaata aagtgttctc atcaatttta tttaaatcaa ctttattttc aattaaatct
    22201 gtcttatcta catcaaaaga gtaaatagta gttgattgag ttttagtttc ttcttttgga
    22261 gtaggtttag ctttgttatt aggaacctct ttttcagtat tgttttcttc ttttggttgt
    22321 tcaacatttg tattgctctt agtttctttt ttagatgtat cacttccatt ttgagcatta
    22381 gtacaaccaa ctgcgaatat agatatagat aatatactta acactaacat tattttctta
    22441 tttttcataa aaatttctcc tctcttaaaa actattctta tatataatta tagtcgttat
    22501 gagcaaatat atgaatacaa aatagtaaca aatttaaaaa atgatttatt taaattaata
    22561 aaactcaaaa taaactaaat tttagtcatt tttatgggaa atcatttaat gtacagtgaa
    22621 aatattgtaa aataaaagta gtgtttttaa aataaatata agttataatt atattataaa
    22681 aaaatgtctt caaaaggtgg gaatagtatg gaaattttga gcttaggaga aaagattaaa
    22741 aaattaagaa aagaaaaaaa catgacatta aaagaattag ctggagatag gataacagca
    22801 gcacaaataa gccatataga gagggataaa tctcatacta gttatgaact gttggaatat
    22861 ctaggcgata agctagatgt aagtgtagaa tacttattag agaccaagga aatgcaatca
    22921 aaaaagataa ctgataattt aatactacag agcgaaattt atataaaaga aaatgaatta
    22981 aacaaggctg aggatcaaat aaaagaagtt ttagatatat gtaagagata cgatttaatg
    23041 gagaactatg gcagatgtaa ttttttaatg gctaatatta atttgaaaaa atctaattat
    23101 aatgatgcta tagaaaactt tgaaaaggca ttgtacttct ttataaaaaa tagtgatagt
    23161 gaaaatatac ttaagtgtta tttaaacata gggaaaatat atatgcagga agacttttat
    23221 aaaggtgcta taagccactt taattttgca gaggaaattt tgtcagagaa taaatttgag
    23281 gatgttaaca tacacaagga actatatagt aagatggcat attgttacat aaaactagat
    23341 aatccaaata tgtcattgaa gtacatagaa aagataaatg aaatagataa tagaaatgat
    23401 agaaaagaag atgtcgatat tttggtgtta aaagcaaata atatgcttga gattggaaaa
    23461 tatgaagaat caagagatta ctttaaaaaa gcactaaaaa tacttgagag tgaggataat
    23521 aaaactggat tagcaaatgt gtatttaaca atttgtgatg tttacagaaa aataggtgaa
    23581 acagatagag tacttgaata ttcacaaaag gtatatgaca taaagaaaaa tgatgaagat
    23641 gaatacatga tgtcaggatt atttaagata atagaagcat atatagataa agaagattat
    23701 gatttagcta gaaaatattg taagatagcc ttagcttcat caataaaaaa taaaaataaa
    23761 ttcaatgaat ataaagcatt gagattctat gctaatatgt ataaaaatca gaatgaagta
    23821 actcttgcaa ttgaatatct gattaaatgc ataaaaatag tatcagattt aggtaacaat
    23881 agaatattgg ccaatttata tatagactta ggtcaattat attcaaatat atcaaaagaa
    23941 aaagagttag aatattatca aaaaggtgta tttatgtaca aaaatttaga aataatgtag
    24001 ggtaaataaa cctataaggg tatagaaaca atctataaca agcaagataa tatctatgat
    24061 aaaatataaa ttgtatgaat atttttaagg agatgaatca gacaatgagt ataaaaatag
    24121 atgcgagagg gcttgcttgt cctaaaccag ttataaatac aaaaagagaa ttggataacc
    24181 tagaagaagg tgttgtagtt acaatagttg ataatgaaac agctaaggag aatatattaa
    24241 aacttgctaa atctttaagt tgtgaagcaa atattgttga cgaaaaagag aattttatat
    24301 ctatagaaat tagaaaaggt aaaaatatac tagataaaca aaatgttgta gataataaag
    24361 aaagtgaatt agacaataca tgtatattta tatcttcaga taagatggga cttggaaatg
    24421 acgaattagg aaaagtgtta ataaaaggat ttatatatac attaacagaa tctaaacctt
    24481 atcctaagta tgtactttta gttaatggag gagtaaaatt aagtgctgaa aatgaagaaa
    24541 ccatagaaaa tctaaaaata cttgagaata tgggtgtaga agttttatct tgtggtactt
    24601 gtttagatta ttataattta aaagacaaat tacaagtagg tacagttaca aatatgtata
    24661 ctatagttga gacattaaag aatgcatcaa ataccatttc tatataatgt atgtttgttt
    24721 aataatataa aactaataat aaagattaac tcaaatagat agtcagaaag gattaagtaa
    24781 tgaatcaaat gtatatagtg tcatttaatt cgacacatca tgcgataaga tcagaaaagt
    24841 tatttggtga aaatagtcta aaagtaatgg ctcttccaac accaagagaa ataacagcaa
    24901 gttgtggaat atcaattaaa ttttcttttg aagatatgga aaagataaaa actattttgg
    24961 ttgaaaataa tgtagatata aaaggaattt attgtataag taaattagaa aatggttcaa
    25021 aagaagtaga gaagttagat taggaggcta attatttatg ccaatggatt taaaaatagg
    25081 tgatattgtt gaattaaaaa agcaacatgc atgtgggtgt aaagagtttg aaatcataag
    25141 aacgggaatg gatataaaga taaaatgtac taaatgttca aggctaataa tgcttgatag
    25201 agagacctta gaaaagagag taaaaaagct aataaaaaag tgataaaaat ttaacactta
    25261 aaaaatgtca aataccgtat attaatatcc aaaattttgg tataataaga attgaagaaa
    25321 acattttcat gggggtgctt taattatggc agttaaatat gcaaaaagaa tgcaaggatt
    25381 acaaggatca gaaatacgtg agcttttaaa acttactcaa caaccacaaa taatatcttt
    25441 tgctggtgga atgccggctc cagagttatt tccagttgag gaaatgaaaa aagtatcagt
    25501 tgcagtgctt gaagaaaatg gaagatcagc tatgcaatat actacaacag aaggatatga
    25561 accattaaga gaaaaaatag cagctagaat gaatgataaa aacaaaacta atgtaaacaa
    25621 agatgatata ttagttacaa gtggttctca acaaggtcta gattttgcag gaaaagtatt
    25681 tattgatgag ggtgatgtaa ttttatgtga aagtccatct tacataggag ctataaacgc
    25741 atttaaatct tatcaaccta aattcataga tgttccaaca gattctgatg gaatgataat
    25801 ggaagaatta gaaaagatac tagaaacaac tgatagaata aaaatgattt acgtaatacc
    25861 tgacttccaa aatccaacag gaagaacttg gccacttgaa agacgtaaaa aattcatgga
    25921 aatagtaaat aaatttgaaa taccagtaat agaagataat ccatatggag atttaagatt
    25981 tgaaggagag actttaccat ctttaaaatc aatggataca aaaggattag taatattctt
    26041 aggaactttc tctaaaatat tctgcccagg atacagatta ggatggactt gtgcttctcc
    26101 agaaatttta tctaaattta actttgcaaa acaaggtgca gacttacaag catcaactat
    26161 atctcaaatg gaagtaagca aatttatgga tatgtatgac ctagatgcac atgttgacaa
    26221 aataaaagca gtttatgtta aacgtagaga tgtaatgctt aagactatgg aagaagagtt
    26281 cccagaagga ttagtattta ctcatccaga aggtggatta tttacatggg tagagcttcc
    26341 aagtaattta aatgctaaag aattaatgcc aaaatgttta gagaagaatg ttgcttatgt
    26401 tgctggagga ggattcttcc ctaatggtgg tagagaaaat actttcagac ttaactattc
    26461 aaatatgcca gaagaaaaaa taatagaagg tataaaaaat atagcagctg tattaaaaga
    26521 agctatgggt gtagaagctt aattaaaaat aataacttat atataataca agggatggtt
    26581 gttgccatcc cttgtttgtt tgaaaagtat ataattcacc ttatactaaa ctttgtccaa
    26641 aatttaaatt gacagaaata agaataaatg ataaaatgtg taggtatgag attttagtct
    26701 catttctctg ctctaagagt gtagagccgt taagtccaaa gggaggtgaa ttatagtgag
    26761 aaattatgaa ttagtttatg tggtaaagcc aaactctgat gaagaagtaa gagaggctat
    26821 actaaacaaa gttaaggaag ttgttgcaac tgacggagaa atagttaaag ttgatacttg
    26881 gggaactaaa aaattagctt atccaatagc taagtttaca gaaggtttct atgtattagt
    26941 taacttcaaa tcagcagtag acgttcctaa agagatagac agaaacttaa agataaatga
    27001 aaacgtaata agacacatga tagttgttgc ttaataactg gttttattat aaaaaatagg
    27061 tggtgttttt atgaatcaag ttgtattagt gggaaggttg actagagacc ctgaattaag
    27121 atacatccca ggtacaggaa caccagtggc atcctttaca atagccattg atagagacta
    27181 tgtaaaaaaa gatggatcta aagaaactga ttttatacct gttgaagtaa tggggaaatc
    27241 tgctgaattt tgtgctaact acataactaa aggtagatta gtagcacttc aaggatctat
    27301 aagagtagac aattatcaga cacaatcagg tgaaaagaga acttttacaa aagtaagtac
    27361 tagatcagta caagctttgg atagtaaaaa taaatcggaa aattcatata gagagagtgc
    27421 tccagctttt gagccaagct ttgaacctca aggtttagac ccacaaggtt tccaagctat
    27481 agatgatgac gatataccat tttaaaaagg agggaaaaaa gtcatgatga ataagaaaag
    27541 acgtaagaaa aaaagagttt gtcaattttg tgctgacaaa aacgctaaaa tagattacaa
    27601 aagtactcaa agattacaaa agtatataac tgaaagagga aagatattac caagaagaat
    27661 atctggaact tgtgctaagc atcaaagaga attaacagtt gctataaaaa gagcgagaaa
    27721 tatagcactt ttaccatata cattagacta aaaaaatgag ccttgtgctc attttttatt
    27781 atatgtattt atatatctaa atgaggcgag ctataaagct cgtttttttg tttatatact
    27841 taaatatatt attatttatg atataatatt atatattaag gagggttgta aacgtgaaaa
    27901 tagataaagg ttctgagata acgagaaaca taaagataat agaatggatg aaaacagaaa
    27961 tattaatgag tgtaagtgat ttgtttaatt tattgtttaa aggggtaaaa ccattagatg
    28021 aagcaattca agatacttta gcaaatataa taatgataac atatctctta gcaaagagat
    28081 taggaattag ttttagagat gtggattata aagtcaagga aaaaataaaa attggtatag
    28141 atgaggacca tagcgttgaa agatggtatg gagatttatc taatttaaaa aaacatatgg
    28201 ataataggga gtgatattaa attgaataat aaaattagac tatctaaggc aatgtctata
    28261 atagttttag ctataataat cgctttagta atagcctata ttccaatgct aggaatattt
    28321 agtatgttag cagctgttcc atatgtaatt ataggtgcta ttactgatag aaagtattct
    28381 cttatatcta ttttggttac attttgtgta ctgattctat ttgcagacat ttcttatgca
    28441 ttaaatatat gtataatgta ttctttacca ggtatagtaa taggaaagat gctaaagaga
    28501 agctttgaac aagaggacag taataaattc gaaccgatat atggtggaac cataatattt
    28561 gtactttcaa tgcttgtata tttttttgta ttaaagacat ttttaaatgt gaatctatta
    28621 gatgaagttt ctaagatgat atcagagatt gtaaatattc aaaaaaatag tttttctgca
    28681 actgaactta aagtgtttga taaaatgaag ccagatgaga ttgtaagtta ttttacaaat
    28741 atgctaccaa tgatgttatt tttacaaggg ttgttatcag cgtttgtcac atattatttg
    28801 agtgtatttt ttataaaaag gattacaaag atgaatataa gatttcctaa gtttgctgat
    28861 ttttatttac caggaaatgc tatactcaca actttcttac tttatttatt agtcttattt
    28921 attcaaatta ttggttcaaa attatataca gaattaataa tgactaattt acagctagtt
    28981 tttaatttaa tgtttgtaat tcaaggtata gcagtttgca tttatttctt aaagaaatgg
    29041 ataagacagg gaccaaataa aattatgttt ttttcaggga taattttatg tttatttgga
    29101 tttatgggaa tatcttttgt tggtatggta gatagtataa ttgactttag aaaggtaaga
    29161 agctataaat ccacttagga ggatagaaat gagtaataaa caaaccttta aattaaatat
    29221 gccagaaata aatttatata taattgttat tggtatttct agtataattt tgctttatta
    29281 caacttgtat gtagggtgtt tatttttctg tatttttgta tatatggttt ttcacaattg
    29341 gagaactact aatattagac gtcatgaatg gacagagtat attcaaaatt tatctttaga
    29401 tatagatgaa acaactaaaa aagccataat aaatcttcca ataccattat gtattttaga
    29461 atttgatgga aatatatcct ggtataatgg aaagttttat gatatgattg gtcaaaaaga
    29521 tttacttgat aaaaatatag aggatatagt taaaaatctt aatttaagaa aagtattaaa
    29581 tgaaaataaa gagatgtaca cagaaataaa ctataaagaa aaagaatata caataattta
    29641 taatgttata aaaaatgatc aagaaaaaaa tcctaaatat ttgatgatat tatactggat
    29701 agacaagact gaatatttaa aagtaaaaca aaattatgat gatgaaaaaa atgcaatgat
    29761 gctaatacaa gtagatggat atgatgaagt attaaaaagt gcagcagaag ataagagagc
    29821 tttaattaat gttgaagtag agaaaatact ttctgcttta gaattaaatt caaatggtgc
    29881 attgagaaga acttcaaaag acaaattctt cttggtaatg cataaaaaag agttaaaaaa
    29941 attggaagct gagaagtttt ctattttaga tacaataaga catattgatt atggaaataa
    30001 tcttcctgtt actataagta taggaattgg tatagatgga gatacattaa atgagaacct
    30061 aaaacttgct acaggtgctc tcgatttagc acttggtaga ggtggtgacc aggctgttgt
    30121 aaaaacaaaa gataaatttg tgttttatgg aggaaaatct aaagctgtag aaaagaaaac
    30181 caaagtaaaa tccagattaa taggtcatgc tttaagagag gttatacaac aaagtgacca
    30241 agtttatata atggggcata aatatcctga tatggatgct atgggagcag cagttggtgt
    30301 ttatgatata tgtaaatcct gtaacaaaac tgcaaacata gttttacaat ctgtaaatga
    30361 atctatagaa atatttataa ataaaataaa tgaaaataat tactataaaa agctgtttat
    30421 tggaaaagag gaagctattg acaactgtac taaaaataca ttagttgtag tagttgatac
    30481 tcatagacca aattatactg aatgtgaaga actgttaaag ctatcagaga aggtagtagt
    30541 tatagaccat catagaagag gtgtggagtt tataaatgat gcagtgcttt tattccatga
    30601 gatatatgta tcctcaacgt gtgaaatggt tacagagtta gttcagtata tggatgaaga
    30661 tgtaacaata aataaactta cagctgaagg gcttttagca ggtataagtc tagatactaa
    30721 aaactttgca ttcaaaacag gtgttaggac ttttgaagct gcttcttacc ttagaaaagt
    30781 tggagcagat actatagagg taaagaaatt cttcaattct gatgtaaaag atttcataat
    30841 aaaagctgaa ataattcaaa gtactaaaat aattaataat agaatatgtt tagcatattc
    30901 aagtactgag atagatagta taaatgttat aatagctcaa actgctgatg agttattaaa
    30961 tatcaaagaa gtagaagctt cctttgtatt aggtgaaaaa gatgatacta tatttataag
    31021 tgcgaggtct ttagggcaaa taaatgtaca tgtacttatg gaaaaattag gaggcggggg
    31081 acacatagat atagctggag cacagttaaa aaatgtttct ctaaaagaag cttataagat
    31141 ggtaaataaa ataatagagg agtatttgga ggaggaagaa tagatgaaag ttatattatt
    31201 aaaagacgta aaaggaactg gtaaaaaggg agaaatgaaa gaagtaagtg atggatatgc
    31261 aagaaatttc ttatttccta aaaagatggc tgtgcaagca gatagtgtag caataaaaga
    31321 attaaatgaa aagaataaat ctaaagaaat aaaagcacaa aaagagtatg aagaagcagt
    31381 tttattaggt aagcaaatgg aagaaattaa tatagaaata tattcaaaag caggagaagg
    31441 tggaagatta tttggttcaa taacttctaa agaaattgct gagcaattaa agaaacaaaa
    31501 agacatagac gtagataaaa gaaaaatatt attagatgaa ccaataagat ctttaggttc
    31561 aactttcgta gaaataaaaa tacatcaaaa agtaactact aaaataagag tggatgtaaa
    31621 agaaaaacag taataactag aggtgattaa gatggaagat atgacgagaa ttcctcctca
    31681 tagtgtagaa tcagaacaat caatattggg ttctatactt ctagataaag atgctataat
    31741 aacggttaca gaaactataa agcctgatga tttctataaa gaggctcaca aaataatata
    31801 tgaatgtatg ataactttaa gtaataaagg tgagcctata gacttgataa cattaacaga
    31861 agaactaaga aaacaagggc atcttaatga tattggagga atcagttata ttacaagtct
    31921 ttctactata gtaccgacga cttcaaatgt aaaatactat gctgatatag taaaagaaaa
    31981 gtctgtactt agaaagctta taaaagcttc taatgaaata ataaatctag gatatagtgg
    32041 agcaactaag attgaagatg ttttagaaca agctgaaaag agtatatttg atatatcaca
    32101 ggagaaaact agtgatgatt ttaaatctat aaacttagtt ttgatggatg cctatgatat
    32161 gatagaaaaa ttatatacta acaagagtga tgtcactggt ataactactg gttttaaaga
    32221 tttaaacaaa aaaataaatg gtcttcaaag gactgattta atattaattg cagctagacc
    32281 agcaatgggt aaaactgcct tttctttaaa cttggttcaa aatgcagcct taaaaggtga
    32341 tgcctctgta gctgtattta gcttagagat gtctaaggaa caattagtac aacgtatgtt
    32401 atcttcacaa tctagtgtag aattaaaaaa aataaagact ggaacactta atgataatga
    32461 ttggcctaga attatagatg ctatggcagt attatcagat gccaaaatac acatagatga
    32521 tactcctggt ataaaaatat cagaactaag gtcaaagtgt agaaagttaa aaatagaaaa
    32581 aggactagat ttagtgctta ttgattatct tcaacttatg gaaggtgaag gtaataatga
    32641 aagcagacaa caagagatat ctaagatatc aaggtcacta aaaatattag caaaagaatt
    32701 aaactgtcct gtagttgcac tatctcagtt atcacgtgca ccagaacaaa gagcagacca
    32761 tagacctatg ttatctgatt taagagagtc tggagcaata gaacaggatg cagatatagt
    32821 tatgttctta tacagggacg aatattatca tgctgattct gagagtaaaa atataggaga
    32881 agtaataata gcaaaaaata gacacggtga aactggttct gtggaacttg tttggcttgg
    32941 tgaagttcaa agatttgggg ataagttgag agacctataa tctaacgaat atccacagaa
    33001 cgtcctttct ttctacagga aaaatgtgga tacatgtcac taaatatgtc caaacattga
    33061 aatttagcta aaaaactatc cacactatcc acagatagcc tgttgataag tgtgaataag
    33121 tagataaagc aagcttttgg cttgctttat ctgtgtataa atattaatta ttaggaggaa
    33181 taatatggaa aaaataagct taaaatatat atatcccaat ataattaaag tacttgatga
    33241 aataaactta tttagagtaa ttgacaataa tttaagagag tctattgttg tttatgctaa
    33301 taatgtggat aatcagtatc atataaacat gactaataca aactttggaa acataattaa
    33361 catatgtaaa ttagaaaaac tttcagatgt ggataaattt atggaaaaag ttataaaata
    33421 tgaaaaagaa ataatagaga aagaagagtt ttcaaaaata gaagaatata tgttaaatat
    33481 tggagaatac taaaaaagtt gaaaaaaata cgaatgtttg atagaataag taagtaaagt
    33541 gttcgagagt atataaaata tagaggtgaa ttacatgaaa acagttgcaa ttgttggttc
    33601 tcaatgggga gatgaaggta aaggtaaagt tatagattat cttgctactc aagcagatgt
    33661 agtagtaaga gggcaaggtg gaaataatgc aggacataca ttagttgtag aaggtaaaaa
    33721 atacgcatta catctaattc catctggagt tttaaatcca aatacagtga atataatcgg
    33781 aaatggaata gtgtttgacc ctaaaggatt tttagaagaa ttggaaatgt ttaaaacgga
    33841 taatataagt acagaaaata taaaaataag tgatagagca catgtcatat tcccatatca
    33901 taaagaacta gatgcattgt cagaagaagc cagaggcgat ttaaagatag gtacaacaaa
    33961 aaaaggtatt ggaccttgtt atatggataa aacagagaga tctggtatta gaatatgtga
    34021 cttaatggat aaagataaat ttgctataaa attaaaagct caaatagatg ctaaaaatga
    34081 aatagttaaa aatatatatg gaaaagaaga attatttgat tttgaaacta tatataacga
    34141 atatctagga tatgcagaac aaataagaaa atatgtggca gatacgtctg ttattgtata
    34201 tgatgcagta agagcaggta aaaaagtatt gtttgaagga gcacaaggga ctttattaga
    34261 tttagattta ggaacttatc catttgttac atcttctcat ccaacatctg gtggatttgc
    34321 aattggtgca ggtataggac caaatatgat aaaagacgtt gttggtatag taaaagcata
    34381 tactacaaga gttggagaag gaccgtttgt tacagagcaa ataaatgaaa ctggagataa
    34441 gataagagaa caaggacatg aatttggggt aactactggt agaccaagaa gatgtgggtg
    34501 gtttgatgca gttatagtta agtatgcagc tagagttaat ggattgacta gtatttcatt
    34561 tatgttactt gatgtattaa ctggatttga taagataaaa gtttgtacgt cttataaaat
    34621 gggcgataag ataataacgg atttcccagc ttcattagat gatttagcaa aatgtgaacc
    34681 tgtatatgaa gaattagatg gatggaatga agatataact caaatagata actttgatga
    34741 ccttccagaa aatgcaaaga aatatgtagc aaaaatagaa gaactagttg gagtaagtgt
    34801 agatatggtt tctgttggtc caaatagagc tcaaactata ataagaagaa atatatttgc
    34861 ttaatatttt atcaattaaa taatttaaaa tagttgaaga agagtatctc aagataatgt
    34921 ttatagttat tagagatgct cttttatatt tgacttacat tgatttttta ttaagttaaa
    34981 gctacttata catattctaa ctgaaattaa agttgaattt atgtagatac atataggttt
    35041 tttaaaaaga attttgttga aaataaatgg ctaaagatga ttttaatgat attctaaaaa
    35101 aagtaaaaaa actattgact aaaaattata tagacgctat aatataactt gtgagtgaaa
    35161 gaaacgacga aaaaagtcga aaaaatgtgg tctattagct cagtcggtag agcacctgac
    35221 ttttaatcag ggtgtcccgc gttcgagtcg cggatagatc accaaaatat ggctcgttgg
    35281 tcaagaggtt aagacaccgc cctttcacgg cggtaacagg ggttcaattc ccctacgagt
    35341 caccagtatg ggactatagc tcagctggga gagcacctgc cttacaagca gggggtcaca
    35401 ggttcgagcc ctgttagtcc caccaaattt tgaattagag ataaatacta gattatatgc
    35461 tggtgtggct caacggtaga gcagctgact tgtaatcagc aggttgtagg ttcgattcct
    35521 atcaccagct ccacaaagta cataaattca aattaatata attttctatg ttacaggata
    35581 cttttaagta tcttttttta atttcatttt tattgtatta aaaatgaaat taaacataca
    35641 acaaaatttt gaattacttg caatgtgata gttttaaatg taaaatttag aatcattcta
    35701 gcataatatt atgtaatata gcaaatttaa tttatagtat caataaatat agactactaa
    35761 gaatgtaaat gatttgttag attaagatac attagatatg taaatagaaa aataaaaagt
    35821 atgttttaat ttatgtggca taagtcttaa acagagaagc aagtttgctc ttacctctct
    35881 atttaaaaat aaaaaaatgt tttttaaggg ctattttatt taaatctttc ccatctcaaa
    35941 tcatctccag taaattctaa aatcctaaac ttatctaaga ttctagagag agttctttga
    36001 gtgtaagtat ttcctatttg agatggtgtt aagttggttg aaataatgat ttttttacca
    36061 gcaacaagtc ttgtatttac aatattgaag atttctccac tagtaaaaga attattaagt
    36121 tcagttccaa ggtcatctat tattaataaa tcacaatcaa acaagttttt ataattatct
    36181 tcacttattt gattatttgt gtctcttcta aatttataat cttcaagaat atctaaaatt
    36241 ctaaaagaag tttgatagat tacaacattg cctttatcta acaattcctt tgcaatacaa
    36301 ttgcacatat aggtctttcc tagtccagta gaaccataaa atagtagatt ttcactatta
    36361 tccttcttaa aatcatgaac aaaattttcg cagatactta aattatttag catattttct
    36421 ctaggagata tttcaccatc agagcctttc ttaggagaaa atatattcaa gttaaaattc
    36481 gaaaaatttt cctgacttaa aatcctatct aaattagaca ttttataagc ttcatttaca
    36541 atttcttgtt tgaggcaaga acatttttct ccattaggta aaaatccttt atctttacaa
    36601 gaaatacatt gaaactttat ttccaagtaa tcaagaggta tgttactttc agataaaagt
    36661 ttttctttct ttacttttaa agactctata ttctctttag tcttctttac aatttcatct
    36721 ttagatttgg gatttaaaag tactatctta gctaaactga gacctatttt agaaatttca
    36781 tcatctatag attttatctc agggattcta ttatatacct cattttttct atgttctaat
    36841 aagagttcat tatcatctct tctcttagca tatttagcaa gtatttttct tattttatcc
    36901 tcattcattt aatcacctac ttaaactttt ctttttgact ttttttaata atctcatcga
    36961 gctcatcaga ggtatactga gtgaatgttt cgttgaaatt atgaaactta gtttttttgt
    37021 aagtattgtt gttttgagta gtattaatct gcttcttatt aatattctcc ttaactatac
    37081 gttcttcctc tttttgcttt aaatcattta aattttttat atttttttca ttccaatttt
    37141 taattatacc atttatataa gatatacttg ggtttgaaat attcttagac ttagaacatg
    37201 catttattat caaatctata tccatattaa atttatcaaa ccaggtgtcc ataagttctt
    37261 tttctgattt tgatggttgt cttgaaaatc ccaattcatt gaaaatcgtt ttatataaaa
    37321 tatatcgttc acttcttacc aaaaagcttt cttcaacatc ttttggcgta tataaatttg
    37381 aatcatacca atttctaata atgccttcaa tgtatttaac tggctttgat gtaccagttt
    37441 tatctttgac gtattcatat gcgcaaagta tcatatcggg gctcatattg tatttattca
    37501 ttatatccat aatactcatc ttttcacttg ggtcgagata tcgcccaact attttattta
    37561 tagaattaaa catttttcta atacttggat tttcagaagt agatacaacc ttatctgtat
    37621 tagattttat agatgaatta ttgcttaata tattctcaat atagaaattt tttaaatcta
    37681 aaaattctat tgaataatta aaattatcat attctccatt gtcatgtatt tttataatct
    37741 tcttttcttc ccagaatttc caagcagata acacatcaga caatggtata tttaggtttt
    37801 tggctattga attattgtcg aacttaggat tagaagtaat atcacatgct tgtctatatc
    37861 ctaaaagata aacttttacg tataacccgt ccgccattgg cataaatata tctataaaga
    37921 tattgggaat agtgatttca cctaaatcta tttcattgct ttctttaaaa aacattttat
    37981 cacctcagat taaattatat cattttttat attatatttg tctgtaaaca aataaaaggt
    38041 cacaagatta gcatgtaaat attttctaaa agtattcatt ttgaaaagga ggagatattt
    38101 tggttataaa attcaaccaa aaagtaagaa gaacattatc agtagcgatt ctatttatgg
    38161 tattaataat aggttgcttt atagaaaagg atgacagttt agaaacatac aaagaaaaaa
    38221 ctaattcaaa aataaatcag tataatatgg atgttatatt tgatgatgag actaagaggt
    38281 taatgtgcaa tcagaatgtt gactacataa ataatacaaa atcaaacata gataaaatat
    38341 atttccatat atatccgaat gctttttcca agaaagattt tgctcctttt gaaaaaagtg
    38401 aaatgacaag ggcttatcct aatggattta acgagggata tatagatata aagaatatat
    38461 taaataataa tagtaaaatg gagtataaaa ttaaaggaga caaaaatgac atattagaaa
    38521 tagaattagg gaaagagtta aaaccaaatg aaagaatgtc attagatata aaatataacg
    38581 taaaaatacc aaattcaatt ggaagatttg gatatggaga aaatactata aatgttacta
    38641 attggtttcc tatagcttgt gtaaatgatg aaaggggatg gaatttaaag agttatgaaa
    38701 ctattggcga cccattttat agtgagacta gcgattttca tgtgaaacta ttgattccaa
    38761 ataaatataa aattgctcat acaggaaaac ttattgatga taaacatgat aataagaaaa
    38821 tgctatatga aatagaagct gaaaacgtta gagattttgc atttatacta agtagtaaat
    38881 ttgatgtaaa caaagtagat tcaaagggag tagctatcaa tacatataat ttaaataaaa
    38941 agctttctaa aaaagcaact gaagtggcaa aagattcaat aaatatattt agtgaattat
    39001 ttggaaagta tccttacaaa gaattttctg ttgtagcaag tgactttttt atagggggga
    39061 tggaataccc tatgcttgtt atgatagacc aaagtttata taatgaaaaa aatgaatttt
    39121 tactagaata tgttattgcc catgagacag cacatcaatg gtggtattct gctgttggaa
    39181 atgatgaaat aagtgaaccc tggttagatg aagcacttac tgaatattct acaatagttt
    39241 attttgaaca aaagtatggt aaagatatgg caaacaagct tataaaaact atggagatac
    39301 agacaaaaag ttatttgagc gaaaatatat ttaagccagc aaatgagtat aaaaattcta
    39361 ctgaatacag cttgaatgtt tatacaaaag gcgcaatagc atttaatgaa ataagaaaag
    39421 aagttggaga taaagtattc tttgagactt taaatgagta ctataataag tataagcata
    39481 aaaatgctaa tggaagagct tttgtggaac tatggaatag taaaggtgta gatataaata
    39541 agattataag tgaatgtaag taaatagtga atgtaagtaa attttgtgca gagtattaaa
    39601 ttttatttaa tactctgttt ttttggtata atataattta taaggcagaa aaagaggtga
    39661 aggaatgcta aagtattgtt cagtagggag tggtagtagt ggtaattgcc actatatagg
    39721 gtataaaaat actaatatac tagtagatgc aggattaagt ggcaagagaa taactacagg
    39781 tcttaaagac attggtgtag atgcagataa attaaaagga atatttataa cacatgagca
    39841 tgttgaccat ataaaaggag caggtatatt atccagaaag tttgatatac cagtatttgc
    39901 taatataaaa acatggtgtt ctatgaagga caaattaggt gacatcaaag ataaaaatat
    39961 gaaagtattt gaaaatgata aaacctactc attaggtgat atcatagtga gacctttttc
    40021 aatagaacat gatgcgtctg atccagttgg atataatttt tatacagaga gtgatgaaaa
    40081 aatgtctata gctactgata taggatgtat aactcaaaat ataaaaaaac atctatataa
    40141 atctaaatta gtagtattgg aatcaaatta tgaccctaat atgcttatga tgggttcata
    40201 tacatatgct ttaaagaaaa gagtaatgtc aagtactggt catttatcca atgaagatgc
    40261 agctaatttc tgcgttgaac ttattaatga aggtacagaa tctatattat tagcacattt
    40321 aagtaaagaa aataattttc ctgagttagc atatgagact tcaaaaggag tattagcatc
    40381 aaatgatata gtagttggac aagatgtaaa actagatgta ctatcacgaa atgatgtttc
    40441 taatgtttat gagatgaagt agaggtgaat aactttgcta aagagaaatt ttgaaaatgt
    40501 tgaggataat aaaattttat actctataaa gcagggtatg attttagcaa tacctgctat
    40561 tatgactggt tcaactgctc ttgtaatttt gaatcttcca ataaaggctt atcaagaata
    40621 tttatcaggc ttgtttaatg gagaggttac aaatattctt aactttataa atgattctac
    40681 tttaggaatt atttcattaa taatattatt aacaataagc tatagttatg gaaaaatata
    40741 tgggagcaag tatacagtac ttgttcctat agttgcaatg tgctcttttt tagtattttc
    40801 acatggtaat gagcttaatt cttatataga aatatttaag acaaagtggt tatttacatc
    40861 tataattgtt tctatgacat cttctgtatt gtttgtaaaa cttacagaat cttttgttac
    40921 aagtgtaaaa tttcatacag aaggggctga tgcagacttt aatatggtag tttcggctat
    40981 agttcctttc ataatagtag tatttttgtt ttctattttt agagtgataa tgataagtct
    41041 aattggcagt tcaaactttc aagatatatt ttataattta ttttcaaatg tttttaataa
    41101 aatgggaaca aaccttatga gtgctctgtt gtttattttt ttaatgcact ttatgtggtt
    41161 ttttgggatt catggtagta atgtattaga tactgtcgca aaaaatttat ttgaaaatag
    41221 tatggcaatt aacataaatt tagttaataa taatcaatta ccaacagaaa tttttactaa
    41281 gacctttttt gatacaatgg ttttattggg aggatgtggc tctttactat gtttagtaat
    41341 tgcaattttt cttagtgaaa aacgtataaa tgtaagaaag ctagctaaaa ttgcttcaat
    41401 accagctctt tttaatatca atgagatgct agttttcggg ataccaattg tttttaacta
    41461 tattatgttt gtaccttttg taattactcc tataatctta accattacaa gttatgtggc
    41521 tatgtctaca ggtattgtac catgtacagt ttcagctgta gaatggacct cacctatatt
    41581 tttaagtgga tatatgtcta caggttcaat aagaggtagt ttgttgcaag tatttaattt
    41641 atgtgttggt gttatgattt atattccgtt tataaaaatg tcgcaaaata gatatacata
    41701 tatgtttaag aataatatag aaaatttaac aaacttatta aaaaggtatg aattaacagg
    41761 tgaacagcct aatcttctaa accataatgg taaaataagt tcaatttcaa aaatgttggc
    41821 atcagacttg aagtttgcta tgaaaagagg agaaatagaa cttttttatc aaccacaagt
    41881 caattataat ggaaatgttg tgggagcaga gggattactt agatggaaac attcaatagg
    41941 agggttcatt tatccaccac tagttataat tttggctaaa gaagaagggt tcttagatga
    42001 gcttggagag tatattatta ataaagcatg tattgattta aagaagagtg aaaagctatt
    42061 gagaaatcct gttaagttct ctgtaaatat atctccagac caacttgatg accctaagtt
    42121 accagagcaa ataaaaaata tcattagtag taatgatata aatcctaata tgttaggtat
    42181 agaaataaca gagcaaattg cattatcagg ttcacaaata attattgaac gtatcaatgc
    42241 gatacataac ttgggaataa agttaattat ggatgatttt gggatggggc atagctctct
    42301 tatatatctt caaaataata actttgatat agttaaattg gatggttcat tagttaaaga
    42361 gatacttaca aataaaagaa gtagtgaaat tataatgact attgtaaatc tttcaaaaaa
    42421 tttagatttt gatatagttg ttgagtatgt tgaaaatata gaccaaaggg ataagttata
    42481 tggtttagga tgtgaaatat atcaaggata ttattatagc aaagcaatac cttttgaaga
    42541 gtttgtagaa tatgcaaatc aagaaagaga gatataattt tataagagct tgtaaattct
    42601 agtaatgcat agatttgtaa taaaattaag tttaggagaa atatatgaat ataagtatag
    42661 tagtagtagg taaaattaaa gaaaaatatt taaaattagg tattgatgag ttcaaaaaaa
    42721 ggctttctaa gtattgtaag ttagaaatta tagagttgga tgatgaaaaa gctccagaga
    42781 atttgagtgt taaggaaatg gaaattataa aagacaaaga aggaaagaaa attttaggga
    42841 agataaagca taatagttat gttatagcct tggctattga tggtaagggt ttatcctctg
    42901 aagaacttgc taagactatg agtgatttag cagttagagg taatagtagt ctctgtttta
    42961 taataggagg ttctctaggg ctttctgatg aggttttagg aagggctgat tataggttat
    43021 ccttttctaa gatgactttt cctcatcaga tgatgagatt gatattgtta gaacagattt
    43081 atagggctta taggataaat aatggagaac cgtatcataa ataaatgata cggtttttgc
    43141 taatttgaca cttaataata ttaaaataac aaaaaagtat tgaaagtata ttgcatttaa
    43201 ggtagaatta aataaaatat tataacatta taatgtttat atagttgtta ataaaaattt
    43261 ggaggaaaat atatgataaa aataatgttg gcctgttcag caggaatgtc tacaagttta
    43321 ttagttacta aaatggaaag tgcagctaaa gaaaatggta tagagtcgca aatttgggca
    43381 ataccagaat caactataca aaatgaaata gaaaaatgtg atgtattatt actaggacca
    43441 caagttagat atgtattacc taaggctcaa gaaattgcta agccatataa tataccagta
    43501 gaggttataa atatgatgca ctatggaaca gttaatggag aagctgtttt aaatagagcg
    43561 atagaactta acaacactaa gtaatataaa ttataatgta tttttaatat ataaattggg
    43621 agaatcaaag gatggatgaa aagattatag aaatatcttt taatataata ggttatgcag
    43681 gtgaaggtaa agggttagct tttgaagcaa taaaagaggc taagaatgga aatatagaaa
    43741 aagcaaaaga attattaaaa gagtctaagg aagttataaa taaagcacat agatatcaaa
    43801 cagaattaat acaaaacgaa gctagtggaa acaggactga aataagtgtc atacttatac
    43861 atgcacagga ccacctaatg aatggtatga attttcaaca gttagctgaa gaaatcgttg
    43921 atttacattt gaaattacaa gataaataaa aattaaagag aataaattaa gagagttctt
    43981 aaaagataca ttatgtgtag cacactaatt gttagattat tgattcaata tttagtgagt
    44041 aatacattag gattatt
//
LOCUS       DACTZW010000030        42503 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.030, whole genome shotgun sequence.
ACCESSION   DACTZW010000030 DACTZW010000000
VERSION     DACTZW010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 42503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42503
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.030"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            210..1427
                     /locus_tag="JAM15_08475"
     CDS             210..1427
                     /locus_tag="JAM15_08475"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase"
                     /protein_id="HAT6798281.1"
                     /translation="MMNVTLTDVKEARETIKNIVKRTDLLESVKLSEKTGANVFYKCE
                     NLQKTGSFKLRGACNKIASLTDEEKANGVIASSAGNHAQGVALGAKMTGIKSTIVMPA
                     TAPLAKVSATKGYGAEVVLNGAVYDDAYAKAVEIQKETGATFLHPFNDKYVIAGQGTI
                     SLEIFEQLDNKVDTILCPVGGGGIISGVAVAAKALNPNVKIVGVQTANIPSMKESIKN
                     GKVTTAFNDTTIADGIAVKTPGDLTFEIINELVDEIVVVEETEIAESILFMMESQKIV
                     SEGAGAVCTAAILSGKYVPAKDENVVCIISGGNIDINTLYRIIGVALAKEGRRYSFST
                     IMEDKPGNFAELTRIISENGGNILSANQGKLSAGEALGKQSAEFILETIDYDHIARIK
                     KAIEEKGFKIIEL"
     gene            1522..1902
                     /locus_tag="JAM15_08480"
     CDS             1522..1902
                     /locus_tag="JAM15_08480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HAT6798282.1"
                     /translation="MKHEVIHTNDAPAALGPYSQAIKAGNLLFVSGQVPLVPETMEVV
                     EGDVQAQTAQSLKNLKAILAESGADFSNVVKTTVFIKDMNEFGAINEVYAEYFGENKP
                     ARACVEVARLPKDVKVEIEVIAVL"
     gene            2186..2668
                     /locus_tag="JAM15_08485"
     CDS             2186..2668
                     /locus_tag="JAM15_08485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAT6798283.1"
                     /translation="MLNFFKKNKSYKLHAVVSGNSINIEKVNDSVFSKKLMGDGVAII
                     PNSNVVVAPCNGKVTVLTESKHAFGMVSDEGVEILVHIGIDTVNLQGEGFKNEVSQGD
                     TVKKGSPIISFEREKINSQGIDCTTIIIVLNHSEFSEINCMVENEVVAGQDTVIEIMK
                     "
     gene            2689..3504
                     /locus_tag="JAM15_08490"
     CDS             2689..3504
                     /locus_tag="JAM15_08490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAT6798284.1"
                     /translation="MRVVKIFNNNALSTVTNDRKEAILLGLGIGFNKRPGDKVNEDKI
                     EKIYYVQDHMQTKFLELLKNVSPEVMDASQQIVSLIPGNEGKFNNKGILSLVEHISFA
                     IDRMKNNVFLPNLMLLDIKMMYSKEFELGVKALEIIYRVCHIHLPEDEAGYIALHFVN
                     LQSNDNLAYDTLKFVKGSIDLIKECYGLELDESSLSTLRFRTHLKFLAQRIFKNEICQ
                     DDKMIEMYDYLINNHPKNKEYLEKLNVYIEKEFRYKLDKPEKIYLLLHLTKIL"
     gene            3555..5105
                     /locus_tag="JAM15_08495"
     CDS             3555..5105
                     /locus_tag="JAM15_08495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAT6798285.1"
                     /translation="MKEKLLGGLETFAKAMVQPLMYLSSAGILMVVGVLLTNDMLLGV
                     LPFFKWEPIQIFGSLIYNCIMAIINNLAVIFAIGIPAALAKKEKHKAALIGFMSYIIY
                     LTASNTMLTSLGQLAKESKMLGLIGTGQATILGIQVVDTSVFGGIILGCIAGYVFNRT
                     SNKTFKGALQIYSGANFSFICMFFVSILIGVVSNFIWPLAQQGIASLANVIKDTGTFG
                     LFLYGFLERILVPTGLHHLIYTPFQFSDLGGVLKVGADTVSGAYAIVMTEMNLPVERF
                     SDSIYYMATGFTKMFGYIGIGAAFIYTAYKQNKKKVKATIIPLIITAVLASVTEPLDF
                     MFVFCAPLLFFVHAVIAGLFIALLKIFDVTALCGGNLLVSIIMNTTVGVEKTHWPVMM
                     ILGLAQIIVYFVVFSFLIKKFNYKTPGREDESTATGEEQSKQLNLDAGIENIIDGLGG
                     KENINTVENCITRLRVNVKDESKINEDIINLTPNSGIVRKGKDIQIIFGLHVHEVRRA
                     VEDFLEAY"
     gene            5202..6554
                     /locus_tag="JAM15_08500"
     CDS             5202..6554
                     /locus_tag="JAM15_08500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HAT6798286.1"
                     /translation="MIITIVGGGSTFTPGIVKSIALREKELELEEIRLFDIDKERQDK
                     VAVVVNWILKEDVKTDVKLTVTNCEKEAYTDATFIFAQMRVGKYEMREQDEKIPLKYG
                     CVGQETCGCGGMAYGLRTIQPMIKVIDDVEKYAKKDYWILNYSNPAAIVSEACRKLRP
                     NARIINICDMPIAIIDMIAESLNINDVHNIRYDYFGLNHFGWFTSIDYKHRDLMEEIK
                     EYIKENKILLPKSYIENLNKSRSTGNRHAVSSWIHVWESVYTMLESFPKYLPNTYLTY
                     YLLSKETVEHSNINRTRANEVMESREKDLFEGVRHYLETGEISEKVFYAGSHGDWISD
                     LAVSIKNDTRSRFLVITENRGAIPNMPYDAMVEIPAYIGKDGPEVIARGPIPLFQQGL
                     MMQQLNSEKLIVEAYIENSYEKALQAFTLNKTIPSMNVAKEILDEMIEVNKEYWPELK
                     "
     gene            6685..7443
                     /locus_tag="JAM15_08505"
     CDS             6685..7443
                     /locus_tag="JAM15_08505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6798287.1"
                     /translation="MNIINKIFWEEDRIGMITNNLEADTHSHCMLQLFLGIEDSIEIT
                     VNEKLVKCNCIIVDKNISHSFSARKKVYYSAIIEPTSIYAEQLTSKMNDFGYWICDND
                     GLEKLRQQGTFLIDNSSKEQYLRFMEMLNNYLNIPITLKHYDDRITELLNLLRTCNCD
                     NHTISSFADKVSLSASRLSHLFKEQIGIPLKSYILFHQMECAFRDLLSGKNVTEASMT
                     AGFDTPSHFAGTVKRMMGMPVSLSLKDSEFLKVY"
     gene            7490..8209
                     /locus_tag="JAM15_08510"
     CDS             7490..8209
                     /locus_tag="JAM15_08510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HAT6798288.1"
                     /translation="MNKEYLEETKMLNYNEPQLKLLVSSKNWLELDDFHKIKSIYEFV
                     QNDILFGYNASDMLSATQVLNDGMGQCNTKATLLMALLRAVNIPCRLHAFDVTKDFQR
                     GATSKLISLLAPKYILHTWVEVFYQDRWIALEGVITDKKYLEAIQKKFFNHGGTFKKY
                     AIATNDLKNTSIDWDGKDTFIQKEAIVYDYGIFPSPDVFFSTHSQHMSKLKNFIYVHL
                     IRKIMTKNVCKARNNYIDKNE"
     gene            complement(8333..9733)
                     /locus_tag="JAM15_08515"
     CDS             complement(8333..9733)
                     /locus_tag="JAM15_08515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAT6798289.1"
                     /translation="METQSNNKKGNLIIAIVMTGAFISSLSQTLLSTALPNIMSDFKI
                     TADVGQWLTTIYLLIAGIIVPTTAYLINRFSTRKLFITSMSIFSIGCIIALFSNNFST
                     MLVARVLQAMGSGSLMPLLQVIILYLCPEEKRGAAMSLVGITVGFAPAIGPTLSGWLV
                     DSFGWHSLFLFLSPIAILDVILSFILLRNVGETQNLKLDIPSIVLSSLGFGGLLIGFT
                     NQGNYGWTNIATYLPILIGIMSLILFTLRQLKSKEPFLELRVFKNKPFLISTILIMIV
                     YASMMSATLMIPLYVQSVRGFSALSSGSLMLPGAILMVVLNPIAGRHLDKYGPHALSI
                     LGTGFLFLGTLSFAFLGRDTSLIHVSLMYCIRMIGISMVLMPLTTWGIKTLDRELISH
                     ATAINNTLRQISGAIGSAILITIMTSATKKAHMSSNMLSNIHGIDVAFSIAATLAFTG
                     LIVSICFIKRYQIIRS"
     gene            complement(9737..10627)
                     /locus_tag="JAM15_08520"
     CDS             complement(9737..10627)
                     /locus_tag="JAM15_08520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAT6798290.1"
                     /translation="MTEKQRLIITIAQKIFDQKGFQNTSISDVVKECKMSKATFYKHF
                     ETKESFICEIINYYDEKFLEIIHSINENNDIPSSEKLNRKIIAVWKNIFSRTTINTYI
                     RENFSEDQRKATSKLQTKSRANLLNEYKLSLFDNYGDKIEKIIFDLVFLLDALIHQFI
                     YIIHVQKREINVYFIAKFTIQILDLVVENMDNLNPLIEKSMFLHKQEDEVYFSLHNKS
                     LFFKTIQDIEELIKTDTSLLENPKLLEAIKKLYVEGKNQQYDSLIMDAMIAYLEKEDA
                     LRPKVLLLNSIKNQLKKETL"
     gene            10906..11553
                     /locus_tag="JAM15_08525"
     CDS             10906..11553
                     /locus_tag="JAM15_08525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HAT6798291.1"
                     /translation="MKKKICVAIIFALFIVFVEMFIDSSSEGSKIMTAELSKYRKGVN
                     VLSINNIIVANKKYSLPKDYSPQESSEARDAFYKMNKDAQKSGLNLKAFSTYRSYEYQ
                     DRLFKSYVKEHGEKEANRFSAKPGESEHQTGLAFDIGGDDQSCWANKKFNNTKEAKWL
                     YENAYKYGFILRYPEGKENITGYMYESWHYRYVGTEHSKNFAMNNLTLEEYLHIN"
     gene            11878..14517
                     /locus_tag="JAM15_08530"
     CDS             11878..14517
                     /locus_tag="JAM15_08530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAT6798292.1"
                     /translation="MSYKSTYQEVIKNLDSSLSGLSKERAEELLEKNGANELKEADKV
                     PTYKLFLESFKDPLVIILLIAALVQIFLGETVESIIIFAVIIINSVLGVVQTKKAESS
                     LESLKNLSAPNAKVIRDNKKMTIPAKNLVVGDIVFLEAGDYIPADGRLIEAQSLKVVE
                     GMLTGESEPVLKHTEKISEDVSLGDQKNMVFSGAVVVYGRGSFVVTGTGMDTEMGKIA
                     GLLESAENKLTPLQQKIEDFSKKLGVGIVILALLIFIIQVARNYFMAGNGEMTQIILD
                     SFMFSVAVAVAAIPEALSSIVTIVLAVGTNSMAKKQAIIRKLPAVETLGSTSVICTDK
                     TGTLTQNKMTVVDYYMYGTNNDELDKEKVNYSYHAKLLTMVSTLCNDSHITSDGKEVG
                     DPTEVALINYSSKNDLDYDKLRSKYIRINEIPFDSDRKLMSTVNSIYGDYIMFTKGAP
                     DIVFSRCKYALKNGSKVDITDEIIEEYKHKNEEFSNRALRVLAFAIKDVPEEDFIPSI
                     DDEHDMTLVGIMAMIDPPREEVMDAVKEAKSAGIKTVMITGDHKTTAAAIAKEIGIME
                     EGDLALTGKELDALSEEQLYEKLENISVYARVSPENKIRIVKAWQHKNNITAMTGDGV
                     NDAPALKQADIGIGMGSGTDVAKDASAMVLVDDNFASIVNAVEVGRTVYSNIIKSITY
                     LFAGNLGAIVSIVFAVFAGWSNPFTALQLLFINLVNDSLPAIALGFEKSEKNIMNKPP
                     RHPDESILAGGTLKAVAIRGCIIGVVTIIAQYIGLQVSPELGVAMAFSTLILARIMQT
                     LPARSNNQTVIKLGFFSNKYVIGAVLVCLGLYSLTLIPVLRGIFSIPTTFGLYQLGIC
                     LGLALISSILMELNKLINRSEVK"
     gene            complement(14575..15678)
                     /locus_tag="JAM15_08535"
     CDS             complement(14575..15678)
                     /locus_tag="JAM15_08535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate aminotransferase family
                     protein"
                     /protein_id="HAT6798293.1"
                     /translation="MKLKINKAIEMQLKKSYAIESGHSEDVFEIDCGEGINTVSYSNK
                     AVEAFNALKFDMIRGYPHSIALKDNIVDYWKDFIALDTDRICLADGSIHVIYLLNRLF
                     IEKGDKVLGYSPQFSEYETDIKMHGATYDYVLLKKEDNFKFNEKEFIEKINPEYKVIY
                     IDNPNNPTGQIIPLSSIENIVKEAAKYDIAVMVDEAYGEYMPKENSAVKLLNNYDNVI
                     ALKTFSKGFGLAGLRAGYAVLPEQLVSPIKKISTPYEVSEISRSIAANLLDDVQFIEE
                     LKEKTKDIKNQLLIPWKNLNIAETSDTVSIMTVEHKNKDIDLQQEFAKLKIRVISGSD
                     FTGLDKNFIRFRMPEEKELPEVIKAFQIIDNIE"
     gene            16039..16860
                     /locus_tag="JAM15_08540"
     CDS             16039..16860
                     /locus_tag="JAM15_08540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAT6798294.1"
                     /translation="MGYKLIVTDMDGTLLGNNHKVTDENKTALQKVIKSGINVTLATG
                     RAFDSAKCNVDFLKEDMPIIACNGSLIREQNGNIIYSNKIDTRTCLNILDVLDKYDIY
                     YQCNSIDSMLSKKIEGREDRLSVFLGSETEVIVKDDLREEIFKKDILKFVIIEEKNPS
                     ILDEIRKELRKVQGIKITSSWPNNIEVMNEGVDKGNAVKILAEKMNIDREDIIAFGDN
                     YNDIEMIKFAGLGVAMGNAEELIKQEADYVTDTNQDSGVAKAIYKFLELKESLSS"
     misc_binding    16939..17150
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            17237..18553
                     /gene="argH"
                     /locus_tag="JAM15_08545"
     CDS             17237..18553
                     /gene="argH"
                     /locus_tag="JAM15_08545"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HAT6798295.1"
                     /translation="MKLWGGRFRKAENQLMEEFNKSFGYDCVLYKKDIEGSVAHVHMQ
                     VKCGLLTEEEGKSITEGLKGILEDVENGKLVLDGEYEDIHSFTEINLIQRIGDVGKKL
                     HTARSRNDQVAVDMRLYAKEKANDLVGLISEFKATIKDVADKNPVMMPGYTHLQRAQV
                     VTFKHHLMAYYSMFDRDEKRIKNAIEILDESPLGCGALAGTTHDIDRSITCEQLGFKK
                     VVDNFMDGVSDRDYLLELMSDFSIIMMHLSRLSEELILWSSQEFGFVEIDDLYTTGSS
                     IMPQKKNPDGAELIRGKTGRVYGNLFGLFTVMKGIPLAYNKDMQEDKEGFFDSVHTLE
                     MCIQIMDRMIATLKVNEDKMKQAVKNGFLNATEVADYLVKNNVAFRDAHGIVGSIVIY
                     CEDNKKAIEDLTLEELHKFSDAFKEDIYDFIDYESILNKGIKKNLK"
     gene            18803..19141
                     /locus_tag="JAM15_08550"
     CDS             18803..19141
                     /locus_tag="JAM15_08550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2325 domain-containing protein"
                     /protein_id="HAT6798296.1"
                     /translation="MNLLVIGGHERMEKDYMVMAKKKGYKTKVYTTMSSKLNNSIGRP
                     DAVVILTSTVSHKMSRTVESQAKKQDILIVRHKNSSKVAFNECLDMVDECLGNCSKCK
                     LKDKQKQKNI"
     gene            complement(19268..20557)
                     /locus_tag="JAM15_08555"
     CDS             complement(19268..20557)
                     /locus_tag="JAM15_08555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HAT6798297.1"
                     /translation="MKRNLSLLLICLLIFTSFLGSSNISFADNEPAIVAKHAVLMDYE
                     SGKILYNKDGNSKLYPASTTKVWTACLVLKEVKDLNQVIEIKDLPQIDGSSMYLKEGE
                     SFTVKQLLDALLVHSANDAAFVLARYVGGGNVQKFIDLMNSEAKKIGATNTHFNNPHG
                     LPDPNHYTTAHDMALIAREAMNNDTFRQIVKTKSLKFEATKAYPYERYFVNTNKFLTS
                     HDKITYKGQPINIKYDIVDGIKTGYTDAAGKCLLSSAVKDGRRVIVAVFNSTNADLYL
                     DSRILIDYGFDNFKCATIVDKEKYTDTKKVLFTKQHELIYEPKNSYRIFLEKDESQGN
                     YDTKTELNKIDLPIKKGAKVGTLNVYNNGKLENSIDLIAKNNLDSSLPFFTGNNILMT
                     FVKIIAGILVLLVLFIIASNIKKKKRKKARSKKNMKK"
     gene            20637..21341
                     /locus_tag="JAM15_08560"
     CDS             20637..21341
                     /locus_tag="JAM15_08560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComE"
                     /protein_id="HAT6798298.1"
                     /translation="MKKKVKFISFFVLFILIISSIIVYKSLIFKDDIYVVSKKNLPNE
                     KTHVVENEIKGEDNNHNKVTKDIDKNFQNNKITIYISGAVNRPGIVTIESDKRLYDAV
                     ELLGGTTKEADLNGVNLSVRLEDEQHYIIPKIGEATSVTSNDDSNKPNQKNKSRGEPK
                     NKSNKNISNESKVNINVATIEELDSLPGVGEATANKILQHREENGQFSSIEEIKNVNG
                     IGDKKYENIKDLICVD"
     gene            21433..22479
                     /gene="selD"
                     /locus_tag="JAM15_08565"
     CDS             21433..22479
                     /gene="selD"
                     /locus_tag="JAM15_08565"
                     /EC_number="2.7.9.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:21481..21483,aa:Sec)
                     /transl_table=11
                     /product="selenide, water dikinase SelD"
                     /protein_id="HAT6798299.1"
                     /translation="MKKEQKKLTEMTTAGGUAAKIGPEVLASVLSQLPKNDNIENLLV
                     GLDTADDAAVYKLNDDMALIQTLDFFTPMVDDPYVFGQIAASNSLSDVYAMGGKPLVA
                     MNIVCFPSCHDMDVLAEILKGGFDKVKESGALLVGGHTVDDKEPKYGLSVSGIVSPNK
                     VLSNATAKPGDKLIITKPIGVGVLNTAMKEGMVEQHIADKVIEIMIHLNKYAAMSFEK
                     FNVNSVTDITGFGLLGHTLEMAKASEVSIEIESKHVPIIEGAIEMAQMGIIPAGMYKN
                     MHYVSKDVEVVGNIEVAVQDILYDPQTSGGLLISVKEELAEELVKDMKLNGAIEAKII
                     GSVVPKGEKYITVL"
     gene            22497..23909
                     /locus_tag="JAM15_08570"
     CDS             22497..23909
                     /locus_tag="JAM15_08570"
                     /EC_number="2.9.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-seryl-tRNA(Sec) selenium transferase"
                     /protein_id="HAT6798300.1"
                     /translation="MIVLSKRELFAMLPSVDEVLSDNRIVEIINEYPRSLVLESVREV
                     IDLKRQFILRLKEDVSNSVTIEFGEIIESAIERVKLNYSLSLKKVINATGTVIHTNLG
                     RSLLSEDIKDELWCAASRYSNLEYDLDNGERGSRYSHLTSTIKRLTGAEDVLVVNNNA
                     AAVLLVLSTMAKGGEAIVSRGELVEVGGSFRIPSIMALSGAELVEVGSTNKTHLKDYK
                     EAITEDTNVLMKVHTSNYRIMGFTESVSIEELVNLGKKYKLPVIEDLGSGVFIDLSKY
                     GLSYEPTVLDSIRQGADVVTFSGDKMLGGPQAGIIVGKKEYIEKMKKNQLTRALRVDK
                     LTICALEATLRMYLDETKAIENIPTLKMLTYKIEELEVKANKLFEKITALNLNANINI
                     EDGFSQVGGGSMPLETISTKVISITPEHMNVSSLEKKLRLSEAHIIARVYDNKYVLDV
                     RTIFDDEFDVIVAELRKAFN"
     gene            24023..25906
                     /gene="selB"
                     /locus_tag="JAM15_08575"
     CDS             24023..25906
                     /gene="selB"
                     /locus_tag="JAM15_08575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenocysteine-specific translation elongation
                     factor"
                     /protein_id="HAT6798301.1"
                     /translation="MKNVVIGTAGHIDHGKTTLIKALTGRETDTLDEEKKRGISINLG
                     FTYFDLPNNRRAGIVDVPGHEKFIKNMLAGASGIDIVLLVVAADEGVMPQTVEHLDIL
                     SFLNIKNGIVVLTKSDTVDDEFRELVKEDICEKIKGTFLEDAEIIEVDSISKRGIDTL
                     IEKIDKMSDDIEDKNENSPARLNIDRVFSIKGFGTVITGTLIEGKISIEDDLVIYPQV
                     LKTKIRSIQVHGENKDTAYAGQRTAINISNVKVDDIKRGDVLAAPNSLEESMMLDVKL
                     SLVNHLDKGLKHWDRLRLYHGTREILCRAVPLDKELIESGESGYVQLRLEESIVSKKG
                     DTFVVRRYSPMETIGGGVIIDPSPKKHKKFDEKVIEALKIKEKGELKDIIEEYLKRNL
                     KNYPNIKEIMSYSGAHEEDVKRALEALISEDKVFIIGNMYMHINQYNKLKENTIKLLS
                     EYHKKYRLRKGILKEEVRSKIESNFKTREMDILLEKLSTENAIKIENNIVSLLDFEVI
                     LNDKQKEIAKKIEKRLKSCGVSSILTIDEVSEGNHNYAEVLESMIGNKVEKLDDLYIM
                     DKDIYENAKNILINYIKENKEITLGEYRDLIDSSRKNCMIILENFDRNKITKRVENKR
                     ILF"
     gene            26011..28749
                     /locus_tag="JAM15_08580"
     CDS             26011..28749
                     /locus_tag="JAM15_08580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation-associated two-component system
                     sensor histidine kinase"
                     /protein_id="HAT6798302.1"
                     /translation="MKNIIPDVKPDIKEREDMSLLFIIMGSVLLLFIIKDIEKYETLL
                     HAIYTIFLVATGVIIFNTTKFKVDSFSTFLGLIFIATGVLECIYLFNSLGIKTKSIME
                     INITISAITDLFPILGVYLSFKFVKDNKQIYSSIILFIATATLTITSLFIISGICDYL
                     GNGKSQYALGVIISIFIIIISIISGIELNSSSNKGKWEYDEKKIFNRIIVIIILSRVP
                     NLLHIVIDNRNVERILSQIIINVALYYLYNYIVSKNIKKTALELHDTNEELTKKTESL
                     KEKNKKLIYETEKIEELKGILMKRESRLQSTLDVAVNSIVVFSKDGEITYANKSFRNT
                     FGDYKEQDKLTDKIKNFNDLIESIHYVFVHEKNAEKLISTSDNKVYQAIFAPLIIASQ
                     TEGVLCVLEDKTKKKEYERKLIEANKRSKDFLESIGDGIVVLEGNNKIYVNNACREIF
                     KNNLESIDFSLVCKSEESIEKRYVIDGEVKYVEMSFSQYTNAGTNKTIIVIRDTTSRK
                     ISQIKLEESQSSYSRFIDILPDGICLLKEDLSINYANKSFLDMLAFTNIDDIKDSNIK
                     LLMNANTEEKMKFTDNMAKVLNENRSILLLEYELINSYDDIVEVELSALPFAIYNTRY
                     IMLIIKDLVHKKYSEQAEKELLERFKTDKIKTEFFANMSHELKTPLNVISSSNQLVDS
                     FYRNEKIKDYNNNIKSHVDLVRQSSYRLQRLINNIIDLTKMESGFYTLKLAKYNIVSV
                     IEDLFMNIEEYALRKDIKILFDTDLEEINVYIDKVEIERIMLNLLSNCIKFTDNGGWI
                     YVSIHYKIDKVIISVKDTGVGIPQDKLELIFEEFSQVDKTLSRNTEGSGIGLAIVKNL
                     VSLHGGDIEVVSEVNKGTEFLISLPMKGFSSEHYTEDKRIYNIQEKIKIEFSDIYY"
     gene            complement(28868..29812)
                     /gene="manA"
                     /locus_tag="JAM15_08585"
     CDS             complement(28868..29812)
                     /gene="manA"
                     /locus_tag="JAM15_08585"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HAT6798303.1"
                     /translation="MEPLFLKPIFMDRIWGGTALKDKFNYEIDSPTTGECWAISSHKN
                     GDCLIENGKYKGKKLSELWNKNRELFGNTPGDKFPLLTKILDANDNLSVQVHPNDEYA
                     KKNENGELGKTECWYVIDCSDDAEIIIGHNAKSHKEFVNMVNNNEWDKLLRKVNIKKG
                     DFFYVPSGTIHAICKGTLILETQQNSDTTYRVYDYDRTDNSGNKRELHVQKSIDVTNV
                     PHINFDTDYKIVSTSDFKCTTFVSNEFFSVYKLDVFGKCNFTHNTPFSLYSVLDGNGK
                     LIHNSVEYNLKKGMHFILPNDFGDFSFEGNLEIICSHI"
     gene            29985..31346
                     /locus_tag="JAM15_08590"
     CDS             29985..31346
                     /locus_tag="JAM15_08590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HAT6798304.1"
                     /translation="MELFKAESKKYEKEFLKLLEQWVSIPSFYDRKTVSKDMPFGKGV
                     YDALNWFENLGRENNFKVKNIDNHAVQIEYGNGKEYVDIFGHCDVVNPGEGWDSEPFK
                     LNIIGDKLVARGVSDNKGPMIVNFLALKMIKDLDINLKRKVRLIAGGNEESGFKCIKH
                     YYSKEPYGVCGFTPDAKFPVLNGEKGGAIIKLISNIDDKSLYISGGIEFNTIPDKVYI
                     KNVEKLGKDNICFDINNISINYDNGNYIVYGKGGHSSKPEKSINPILATIKLLSENID
                     EKWTKDLYKLINQDNINGNLFGLNIEGKCGILSIVPTIINIVDGKLEVVLSVRYPEIL
                     TIEDIIKKFNLYMEQNNINKFELIGENLKQANYIDRNSKLVRSLHDIYIKYSGDLKND
                     VRVTSAGSYASEMNNSVIFGCEFPDGSFGNVHSANEFASLDRFITAIGIYAEAIITLC
                     NKI"
     gene            31434..33323
                     /locus_tag="JAM15_08595"
     CDS             31434..33323
                     /locus_tag="JAM15_08595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HAT6798305.1"
                     /translation="MITKKHAIIVKSLSNKDGYMTSNELAIKLDVSTKTIKRYIADLN
                     SVLSKYDLVIASSRGIGYKLSGSKNNIARAVKEANKYIDGFLDDSEESRMSNIICMLI
                     NRNYMSIEAMAEELNLSIAAINKLSSKLKRKLEKYDLVIKSKPYYGSYIHGEEINIRQ
                     LITDYAIKLDEKSKVKVFLDDISENDIYCIESILEKHLREKDTIISDKDFNLLLSKII
                     VSVFRSKRGHSNNINLMDTSYRFHNYYFIENLMKEISDKIGFKLIEDEVIYISNYSGV
                     IAYKGTQGRKNTSEIEERISSVISSALQDIFLISGSDYTKDDEFMVAISDHIKRFLNR
                     ARANVKSNNPLLHQIKEKFPIAFNLAVFLSNKLETEFNLKLDEDELGYIAIHFAASNE
                     RMKKNTSKKICIVCHYGIGTGQLISEKLKQNISDLSVVGVYPVRYLDMAISQDVDLIV
                     STVELKGYEKPVLYIENIFDDSLIENVNKAFYEKEERRKIISNMFDEKAFFSIKASTK
                     EEVIISLSNKLKERDFIEESSIKSIIDRENISSTEIGNLVAIPHTIVKGDKKSIIGVG
                     ILENPIIWDKQEVQLVFMVFFNTKEKHNFSIFKYLYNFIKDEGGVRGIIKICDFNKLM
                     ALIGN"
     gene            33338..33793
                     /locus_tag="JAM15_08600"
     CDS             33338..33793
                     /locus_tag="JAM15_08600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAT6798306.1"
                     /translation="MGTNIFNKEYVFLNVDAKSKVEVLKFISKKAKDLNLAEDESLVY
                     EGLMAREEQFTTNLGESIAIPHTKNDAIENPAVVVLKFNEDVVWNEGEDKVKLAISLL
                     MPGKSKENIHLKLLSSLSRKLINKEFKDSLLKSDNVEEISNLINEALGL"
     gene            33852..34169
                     /locus_tag="JAM15_08605"
     CDS             33852..34169
                     /locus_tag="JAM15_08605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HAT6798307.1"
                     /translation="MNKKLVALCACPMGLAHTFMAAEAIEQAAKALGYEAKVETQGAD
                     GVQNELTRDDILGATMIIHAVAITPEGMERFDGCEVYEVELQEAIKNAEGVIKEIEED
                     LGI"
     gene            34194..35456
                     /locus_tag="JAM15_08610"
     CDS             34194..35456
                     /locus_tag="JAM15_08610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HAT6798308.1"
                     /translation="MAIKKKVINSSGASTTGGNNVGKSTPSSPTQSKGNGKWKEISKH
                     IMTGISYMIPVLVMGGLIGALSQLIPYAILGLDPSVGIVDAMNSGEFTGFKLSLLNIA
                     QLMSNFGFTLFGFAIPLFAAFCANSIGGKTALIAGFIGGYIANKPVGVPQFIDGQWTE
                     VVPVASGFLGAILIAFIIGYFVKWLNKSIKVSHNWLAFKTTFLIPLIASLACMVLMIF
                     IITPFGGLINESMKNFLTAAGAAGEYVYATALAAATAFDLGGPINKAAGFVALGLTTE
                     NVLPITARTIAIVVPPIGLGLTTLLDKRLVGRRVYDRQFYQAGKTSIFLSFMGISEGA
                     IPFALERPGFVIPLNIVGSVIGAITGIILGAIQWFPESAIWAWPLVDNLFGYIIGIAV
                     GAIFIAVGNIFYRNKLIKDGKLVVDYID"
     gene            35561..36625
                     /locus_tag="JAM15_08615"
     CDS             35561..36625
                     /locus_tag="JAM15_08615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HAT6798309.1"
                     /translation="MDKIEKVREYFREYDIDGFLINSPTNKFYVGNLFSSSGYVFITK
                     ESQYIIVDFRYFEEIKRKSSLFNVVLMDKTRTHFDIINDICREQNIKEIGFEGNEVSF
                     DLYRSMSNKLSATLKSVDLSTLRETKNEDEIKYIKKACEIVDATFYHIVDFIKIGMTE
                     KQVENEIVRIIKDLGGQKESFDTIVASGLRGALPHGKASEKVIEYGDFVTFDFGAKYN
                     NYCSDITRTICMGTINKELEEIYNIVRKANEECIRVLRPGMTTGEIDKVARDIIGSYG
                     YANNFGHNLGHGVGIMVHEYPALAPESNEVLKEGMIVTIEPGIYVPSLGGVRIEDDVL
                     ITQDGCMRLTTSTKDLIVVS"
     gene            36679..37857
                     /locus_tag="JAM15_08620"
     CDS             36679..37857
                     /locus_tag="JAM15_08620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative C-S lyase"
                     /protein_id="HAT6798310.1"
                     /translation="MYNFDDKPDRVSEKCRKWDLNIIRDKFGDIREDFVPMWIADMDF
                     KIPTEIENKFIEAVRRGVFGYTYCYDEFYDSVIGWQKNMHEVNVEKEWITLTYGTVST
                     LHYVVQAFCKKGDSIILNTPVYDPFESSAKKQGVNVICNTLDVVNDRYYINFDKLEVQ
                     IKENKPKLMMFCTPHNPSGRIWTIEEMTRVATICKENNVILVADEVHAEHIHYGKFNS
                     ILKIGKELLENVILLTSPNKGFNLGGLKTSYSIVINKDIRDKFRNKLKQNSITSPNVF
                     GIIGLITAYNECHEWLSGVNEYIKSNYELLETWVNKYNKIKLMKMESSYLAWMDISGL
                     GISASEFTDKLAIDTGVLLEDGSHFVKDGEKYVRINLGTQKENVIEALNRMDLFLKSL
                     "
     gene            38053..38250
                     /locus_tag="JAM15_08625"
     CDS             38053..38250
                     /locus_tag="JAM15_08625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005809912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6798311.1"
                     /translation="MKNCVEALRKKKGLNQEDFAKILKVSRQTISSIENGKYNPSLEL
                     AFQISDFFEMSIEEIFLWKEI"
     gene            38254..38688
                     /locus_tag="JAM15_08630"
     CDS             38254..38688
                     /locus_tag="JAM15_08630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tellurium resistance protein TerC"
                     /protein_id="HAT6798312.1"
                     /translation="MEKRNLRIGIVYIVLGVTFLFSCLMTKDKLSSLLVGLAAGFGFN
                     GISIIYRYFYWNKHKEEYREKLEEEKINLQDERNVMYRDKAGRYAYIVCMIIIPISAF
                     VFAVLNALDIYNSLVIIIYLSVLWIVLYVVGVIYYRKLKNNE"
     gene            complement(38862..39920)
                     /locus_tag="JAM15_08635"
     CDS             complement(38862..39920)
                     /locus_tag="JAM15_08635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HAT6798313.1"
                     /translation="MNKKKITFIFVILILALILFSFFRSSSQNTKYSKTSYYLGTVNE
                     VTVFNVKESKSDKILNECDSILRYIDNKMSTHIPGSDVSKINDNAGKKFVRVSDDTFF
                     VVKEAIQYSKLSDGYFDITIGPLSNLWAIGTDKAKVPSDSEIQKLLPLIDYKNIILDE
                     KNKSIKLTKENMKIDLGAIAKGYAADKIVAYLKSEDVKKGLVNLGGNIFTLEDGKNDK
                     PFKIGIQDPTSKNGESIGNIETTNKSVVTSGIYERFIEKDGKIYHHMLNPFTGYPFEN
                     NLSSVTIISDKSINCDALSTSTFGLGLEKGMDLINKIDNVDAIFITKDKKVYLTKGIK
                     DNFKLTDKSFSIEKLNKQ"
     gene            39987..40358
                     /locus_tag="JAM15_08640"
     CDS             39987..40358
                     /locus_tag="JAM15_08640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HAT6798314.1"
                     /translation="MKKKDILLILGILVVITACYGIINVINSKNAGNIEIYVDNKLYK
                     TVSINAKEEFKIENRGGYNIVKIHDKGVEIVDASCPDKVCVHTGFINKPSQSIVCIPN
                     RVSIKINTNEKNDNQEDIISK"
     gene            40395..41069
                     /locus_tag="JAM15_08645"
     CDS             40395..41069
                     /locus_tag="JAM15_08645"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005978738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HAT6798315.1"
                     /translation="MVNLGNDWDELLKEEFEKDYYLNLRKFLIEEYKTRQIFPNMHNI
                     YEALKHTSYKDTKVLILGQDPYHGDNQAHGLAFSVQPQVKTPPSLLNMYKELKDDLGC
                     FIPNNGYLMPWADQGVLLLNTALTVRAHEANSHKNKGWEIFTDRVISILSEREDPVIF
                     VLWGSNARKKVELIDTSKHYILEAPHPSPLSASKGFFGCKHFSKINEILKKLGKEPIN
                     WQIENM"
     gene            41317..42156
                     /locus_tag="JAM15_08650"
     CDS             41317..42156
                     /locus_tag="JAM15_08650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF348 domain-containing protein"
                     /protein_id="HAT6798316.1"
                     /translation="MNFKKLSNAKVSVMAVVLSVGILSGYSALNKQVTLVVRGEERTI
                     STFSSNVGDLLESQNISYDANDIVTLDENTKLSNGDKIEVIDVKEKTVVETKDIPFEV
                     TVVEDGSLLKGDSKVKEEGKSGKSELIYKETYHNGKKVEKEFVKKVVKAEPVNKVVSK
                     GTKVEMQVASSRGESSRRMASSSSSSSSSNNGKNMRVVATAYTGHSITATGTKPKWGT
                     IAVDPKVIPYGTKVYIPQFDMVFTAEDCGGAIKGNKIDIYMNDSKTVYNWGRKTIDIR
                     ILK"
     gene            42400..42496
                     /locus_tag="JAM15_08655"
     tRNA            42400..42496
                     /locus_tag="JAM15_08655"
                     /product="tRNA-Sec"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:42434..42436,aa:Sec,seq:tca)
BASE COUNT        16636 a         4670 c         7409 g        13788 t
ORIGIN      
        1 aatgtaaaaa atatttttaa attatcattt aatgtaattt aaatgaattg aagatatatg
       61 tttattgtat gcaattgttg tatttttagg ttttttgtga ttaattaaaa aattataaaa
      121 atcgtttaca tgttgatttt taaaaaaaaa agatatagaa ttatatagaa agtaataaac
      181 aaaaattgga tttacgggag tggaatgaaa tgatgaatgt taccttaaca gatgtgaaag
      241 aggctagaga gaccattaag aacatagtaa aaagaactga cttacttgaa agtgttaaac
      301 ttagcgaaaa aacaggagca aatgtgttct ataaatgtga gaatcttcaa aaaacaggtt
      361 cttttaaatt aagaggagct tgtaacaaaa tagcgagttt aacagatgaa gaaaaggcaa
      421 atggagttat agcttcaagt gcagggaatc atgctcaagg agttgcattg ggagcaaaaa
      481 tgactggtat aaaatctaca atagtaatgc cagcaactgc gcctttagca aaagttagtg
      541 caactaaagg ttatggagca gaagtagttt taaatggtgc ggtttatgat gatgcatatg
      601 caaaagctgt tgaaatacaa aaagaaacag gagcaacttt cttacatcca ttcaatgata
      661 agtatgttat agcaggacaa ggaactatat ctcttgaaat tttcgaacaa ttagacaata
      721 aagttgatac tatactatgc ccagttggtg gaggaggaat catctctggt gttgctgttg
      781 cagcaaaagc attaaatcct aatgtaaaaa tagtcggtgt tcaaactgca aatatacctt
      841 caatgaaaga gtcaataaaa aatggaaaag taacaacagc atttaatgat actacaatag
      901 ctgatggtat agctgttaaa actccaggag atttaacttt tgaaataata aatgaattgg
      961 ttgatgaaat agtagtggtt gaagagacag aaattgcaga atcaatatta tttatgatgg
     1021 aaagtcaaaa aatagtttca gaaggtgctg gtgctgtatg tacagctgct atattaagtg
     1081 gtaagtatgt accagcaaaa gatgaaaatg tagtttgtat aatatctggt ggtaatatag
     1141 acataaatac gttatataga ataataggtg ttgctttagc taaagaagga agaagatatt
     1201 catttagtac aattatggaa gataagccag gaaactttgc tgagttaact agaataataa
     1261 gtgagaatgg tggaaacatt ttaagtgcta atcaaggtaa attatcagca ggggaagctc
     1321 taggaaaaca aagtgcggaa tttatattag agacaataga ttatgaccat atagctagaa
     1381 taaagaaagc tatagaagaa aaaggtttta aaattataga attataataa aaagtgtata
     1441 taatatacaa gaaaaatagt ataatagtgt atgaagatac attttatgtg tattagatta
     1501 acgaattagg aggattttaa aatgaaacat gaagtaatac atactaatga tgcaccagca
     1561 gctttaggac catattctca agctataaaa gctggaaact tattatttgt atctggacaa
     1621 gttcctcttg taccagagac tatggaagta gttgaaggag atgtacaagc tcaaactgct
     1681 caatctttaa aaaatcttaa agctatatta gctgaaagtg gagctgattt ttcaaatgta
     1741 gttaagacta cagtatttat aaaagatatg aatgaatttg gggctataaa cgaagtttat
     1801 gctgaatatt ttggagaaaa taaaccagca agagcttgtg tagaagttgc tagattacca
     1861 aaagacgtta aagttgaaat agaagtaata gctgtattat aaaaatacaa tatttttaat
     1921 ttgaaaaggc tgaaaaacta tattctagtg attcagtctt tttataaaaa aataaatcac
     1981 aataaagaac atgataaata ttgtcgaatt aaaaaataaa attaaaataa atattgcaat
     2041 atttttgaga aggttttata atgagtatat aatttgaaac gtgtaactat taaattaggc
     2101 atgagttctt ggatattttt atcctgagga ttcatgcctt ttttgtattg aaattcaaaa
     2161 atctatttaa taaggaggaa gtattgtgtt aaattttttc aagaaaaata aaagctataa
     2221 gttacatgca gtagtgagtg gtaacagcat taatattgag aaagtaaacg attctgtgtt
     2281 ttcaaaaaag ttaatgggag atggagttgc aattattcct aatagtaatg ttgttgtagc
     2341 cccttgtaat ggtaaagtaa ctgtgcttac agaatcaaag catgcctttg gtatggtctc
     2401 agatgagggt gttgaaatat tagtccacat aggaattgat acagttaatt tacagggtga
     2461 ggggtttaaa aatgaagtgt ctcaaggaga tactgttaaa aaaggtagtc caataataag
     2521 ttttgaaaga gaaaaaataa attctcaggg aattgattgt acaacaataa taattgtatt
     2581 aaatcatagc gaattttcag aaataaattg catggtagaa aatgaagttg ttgcagggca
     2641 agatactgtt attgaaatta tgaaataata ggaagggatt aattcaatat gagagtagta
     2701 aaaatcttta ataataatgc attatctaca gtaactaatg ataggaaaga agctatttta
     2761 ctaggtcttg gtataggttt taataaacgt ccaggagata aagttaatga agataaaata
     2821 gaaaagattt attatgttca agaccacatg caaacaaaat ttttagaatt attaaaaaat
     2881 gttagtccag aagtgatgga tgcttcacaa caaattgtaa gtcttatacc aggaaatgag
     2941 ggaaaattta ataataaagg gatattatca ttagtggaac atattagttt tgcaatagat
     3001 agaatgaaaa ataatgtttt tttacctaat ttaatgcttt tggatataaa gatgatgtat
     3061 tcaaaagagt ttgaattagg agtaaaagct ttagaaatta tatatagagt atgtcatatc
     3121 catttgcctg aagatgaagc aggttacata gctttacatt ttgtcaattt acaatcaaat
     3181 gataatttgg catatgatac tttaaaattt gtaaaaggta gtattgattt gattaaagaa
     3241 tgttatggat tagaattaga cgaatcgagt ttaagtacat tacgttttag aactcatctt
     3301 aaatttcttg ctcaaagaat ttttaagaat gaaatttgtc aggatgataa aatgattgaa
     3361 atgtatgatt atttaattaa caatcatcct aaaaataaag aatatttaga aaagttaaat
     3421 gtatatattg aaaaggagtt taggtataaa ttagataaac ctgaaaaaat ttatctacta
     3481 ctacacctaa caaaaatctt ataagaatga gatgaattag taatagaaat atataatttt
     3541 agggggggat aagattgaaa gaaaaactac ttggaggact ggaaacattt gcaaaggcaa
     3601 tggttcagcc attaatgtat ttatcgagtg caggaatatt aatggtggta ggtgtactac
     3661 ttacaaatga tatgttatta ggagtacttc cattttttaa atgggagcca attcaaatat
     3721 ttggaagcct aatttataac tgtataatgg ctattattaa taatcttgct gttatatttg
     3781 ctataggtat tcctgctgca ctagcaaaaa aagagaagca caaagcagcg ttaataggat
     3841 ttatgagtta tataatatac cttacagctt ctaacactat gttaacatca ctaggtcaac
     3901 tagcaaaaga aagcaagatg cttggactga tagggactgg acaagctact attttaggta
     3961 ttcaagttgt agatacaagt gtatttggtg gaattatttt agggtgtata gctggatatg
     4021 tatttaatcg tacaagcaac aaaacattta aaggagcttt acagatatac tcgggagcaa
     4081 attttagttt tatatgcatg ttctttgtat ccattttaat tggagttgtg agtaacttta
     4141 tatggccatt agctcaacaa ggaatagctt ctcttgcaaa tgtcatcaaa gatacaggta
     4201 catttggttt attcttatat ggttttttag agagaatatt agtaccaact ggacttcatc
     4261 atttaatcta tacaccattt cagttttctg atttaggagg agtgcttaaa gttggtgcag
     4321 atacagtttc aggagcctat gctatagtta tgacagaaat gaatttacca gttgagcgtt
     4381 tctcagatag tatatactac atggcaactg gatttacaaa gatgtttggt tatataggta
     4441 taggagctgc ctttatttat actgcatata agcaaaataa gaagaaggtt aaggcaacga
     4501 ttattccact aataattacg gcagtattag cctctgtaac agaaccatta gactttatgt
     4561 ttgtattctg tgcaccactt ttattctttg tacatgcagt tatagctggt ctttttatag
     4621 ctttattaaa aatatttgat gttactgcat tatgtggagg gaacttatta gtatcaatta
     4681 taatgaatac tacagtaggt gtagaaaaaa cacactggcc agtaatgatg atattaggac
     4741 ttgcacaaat tattgtatat tttgtagtat ttagtttttt aattaagaaa tttaattata
     4801 aaactccagg tcgtgaagat gagagtacag ctacaggcga agaacaatca aaacaactta
     4861 atttagatgc aggtatagaa aatataattg atgggttagg cggaaaagaa aatattaata
     4921 cagtagaaaa ttgcatcact agattacgtg ttaatgtaaa agatgaaagt aagattaatg
     4981 aagatataat taatttaacg ccaaatagcg ggattgtaag gaaaggaaaa gatatacaaa
     5041 taatttttgg acttcatgtg catgaggtaa gacgtgcagt agaagatttt ttagaagctt
     5101 attaaagata tatatttata tagcaagggt aaataacagc tttaagtgct gtttactatt
     5161 tattaaagat acatataatt tatagaggag gaataattat tatgattatt actattgttg
     5221 gtggaggaag cacatttact ccaggtattg ttaagtcaat tgcgttaaga gaaaaagagt
     5281 tagagcttga ggaaattcgc ttatttgaca ttgataaaga acgccaagat aaagtagctg
     5341 tagttgtcaa ctggatacta aaagaagatg ttaaaacaga tgttaaacta actgtaacta
     5401 attgtgaaaa agaagcgtat acagatgcta catttatatt tgcacaaatg cgtgttggta
     5461 aatatgaaat gcgtgagcag gatgaaaaaa ttccattgaa atatggttgt gtaggtcaag
     5521 aaacttgtgg ttgtggaggg atggcatacg gactgcgtac aatacaacca atgataaagg
     5581 ttattgatga tgtagagaaa tatgctaaaa aagattattg gatattaaat tactctaatc
     5641 ctgctgcaat cgtttctgaa gcttgtcgta agttaagacc aaatgcaagg attataaata
     5701 tctgtgatat gccaatagct attatagata tgatagcgga gtcattaaat atcaatgacg
     5761 ttcataatat acgctatgat tattttggtc taaatcattt tggctggttt acttcaatag
     5821 attataaaca tagagactta atggaagaga ttaaggaata cataaaagaa aataaaatat
     5881 tattaccaaa atcttatata gaaaacttaa ataaaagtcg tagtacagga aatcgccatg
     5941 ctgtaagtag ctggatacat gtttgggaat ctgtttatac aatgttagaa agcttcccaa
     6001 aatatctgcc aaacacttat ttaacatact atcttttaag taaagaaaca gtggaacatt
     6061 caaacataaa tcgtactcgt gcaaatgagg ttatggaaag ccgtgaaaaa gacttatttg
     6121 aaggtgtgag acattactta gaaactggag aaatttctga aaaagtattt tatgcaggtt
     6181 cacatggaga ttggattagt gatttggcag tttcaattaa aaatgataca cgtagtcgtt
     6241 ttttagttat aactgaaaat cgtggagcta taccaaacat gccatatgat gcaatggtag
     6301 aaattccagc atatattggt aaagatggtc cagaagttat tgctcgaggt ccaatacctc
     6361 tattccaaca aggattaatg atgcaacaac ttaacagtga aaaattgata gtagaagctt
     6421 atatagaaaa tagttatgaa aaagctttac aagcattcac attaaataaa actattccaa
     6481 gtatgaatgt tgctaaagaa attttggatg aaatgataga agttaataag gaatactggc
     6541 cagaattaaa atagtaggat aaaagaaagg gtttttattt aataattaga tatgttttca
     6601 gagtctttta tcaaaatgta ttcacaaaca tatggcaata tattaaaata aagagtgata
     6661 tttttagaag aatggggtga tgcaatgaac attataaata aaattttttg ggaagaagat
     6721 aggattggca tgattacaaa taatttagag gcagatacac atagccactg tatgttacaa
     6781 ctgttcttag ggatagaaga cagcattgaa ataacagtca atgaaaaatt agttaaatgt
     6841 aattgtatca tagtagataa aaatatctct cattcatttt cagcaagaaa aaaagtttat
     6901 tactctgcta ttattgaacc tacatctata tatgcagaac agcttacctc aaaaatgaat
     6961 gattttggct actggatatg tgacaatgat ggattagaga aattacgtca acaaggaact
     7021 tttttgatag ataactctag taaagaacaa tatttaagat ttatggaaat gcttaataac
     7081 tatttgaata tacctataac tctcaaacat tatgatgaca gaattactga attgctcaat
     7141 ttattacgta cttgtaattg tgataatcat actatttcaa gttttgcaga taaagtgtcc
     7201 ctatcagcaa gtagattatc acatctgttt aaagaacaaa tagggatacc tttaaaaagc
     7261 tatatcttat ttcatcaaat ggagtgtgct tttagagact tactttctgg gaaaaatgtt
     7321 accgaagctt ctatgactgc tggattcgat actccatcac actttgcagg gacagttaag
     7381 cgaatgatgg gaatgcctgt ttctttatct ttgaaagata gcgaattttt gaaagtatat
     7441 taaatattct tgttatataa tgaagttgta ctaagaaagg ggctttgtta tgaataaaga
     7501 atatttagag gaaacaaaaa tgttaaatta taatgaacca caacttaagc ttttggtatc
     7561 atcaaagaat tggttggaat tagatgattt tcataaaata aaatctattt atgagtttgt
     7621 acagaatgat attttatttg gatataatgc ttctgatatg ttaagcgcaa cacaggtatt
     7681 aaatgatggt atgggacaat gcaatacaaa agctactctt ttaatggcat tattacgtgc
     7741 agtgaatatc ccttgtaggc ttcatgcttt tgatgtaaca aaagattttc aacgaggtgc
     7801 tacatccaaa ttgatttcac tattagcacc aaaatatatt cttcatactt gggtagaggt
     7861 attttatcaa gataggtgga ttgctctgga gggtgtcata actgataaaa aatatttaga
     7921 agcaattcag aagaaatttt ttaatcatgg tggaacgttt aaaaagtatg caatagctac
     7981 aaatgatttg aaaaatacat ctattgattg ggatggtaaa gatactttta tccaaaaaga
     8041 agctatcgtg tatgattatg gtatttttcc atcaccagat gtattttttt ctactcattc
     8101 acaacatatg tcaaaattaa aaaatttcat atatgtacat cttatcagaa aaataatgac
     8161 aaaaaatgta tgtaaggcta gaaacaatta tattgataaa aacgaatgag tgtttaagag
     8221 gtaactatat aggaaatata tagaataatt aaaactgtac tggttaaaat gaataaaaag
     8281 gagttatcat agagcaaact taaattgttc ataggataac tccttttttg tattaacttc
     8341 taataatttg atatcttttt ataaaacata tagatacaat taaaccagta aatgcaagag
     8401 tagctgctat tgaaaatgca acatctattc catgaatgtt agacaacatg tttgaactca
     8461 tatgagcttt cttagtagca cttgtcatta tagtaataag tatagcagaa cctatagcgc
     8521 cagatatctg acggagtgtg ttattaattg ctgtggcatg agatataagt tctctatcta
     8581 atgttttaat tccccatgta gttaatggca ttaaaaccat tgaaatacca atcatacgaa
     8641 tacaatacat caatgacaca tgaattaaag atgtatccct gcctaaaaaa gcgaaggata
     8701 aagttcctaa aaacaaaaat cctgttccta atattgatag agcatgaggt ccatatttat
     8761 ctaaatgacg tcctgcaatt ggattgagta caaccatcaa tatagcacca ggtaacatta
     8821 atgaacctga agataatgca gaaaatcctc ttacagattg aacgtataga ggaatcatta
     8881 atgtagcaga catcattgag gcatatacaa tcataattaa tattgtagaa ataagaaatg
     8941 gtttattttt aaaaaccctc aattctaaaa aaggttcttt agattttaat tgacgcaatg
     9001 taaataaaat taatgacata attcctatta atattggtaa atatgtggca atattagtcc
     9061 acccataatt accttgatta gtaaatccaa ttaataaacc accaaaacct agagatgata
     9121 gtactattga aggtatatct aattttaagt tttgagtttc cccaacattt cttaatagaa
     9181 taaatgatag tataacatct aatatagcaa taggggaaag aaacagaaat aagctatgcc
     9241 aaccaaatga atctactaac catcctgata aagttggacc tattgctgga gcaaatccta
     9301 ctgtaatacc aactaaactc atagctgcac cacgtttttc ctcagggcat aaatagagta
     9361 taataacttg taaaagtggc attagagaac cagaacccat tgcctgcaat acacgagcaa
     9421 ccaacatagt tgaaaaatta ttagaaaaaa gtgcaataat acatcctata gaaaagatag
     9481 acattgatgt aataaataac tttctagtac taaatcgatt tattaaataa gctgttgtgg
     9541 gtacaataat acctgcaata agtagataaa ttgttgttaa ccactgacca acatcagcag
     9601 taattttaaa atctgacatt atattaggta atgctgttga caatagtgtt tgactgagag
     9661 aacttataaa agcaccagtc attacaattg ctattattaa atttcctttt ttattgttac
     9721 tttgggtttc cataatttat aacgtctcct tttttaattg atttttaatg ctgttcaata
     9781 aaagtacttt tggtcttaaa gcgtcttctt tttctaaata tgcaatcatt gcatccataa
     9841 ttaaagaatc atattgttga ttttttccct cgacgtataa tttttttatt gcttctagta
     9901 atttaggatt ttcaaggaga gaagtatcag ttttgattag ttcttctata tcttgtatcg
     9961 ttttaaaaaa tagcgattta ttatgaaggg aaaagtaaac ttcatcttct tgtttatgta
    10021 aaaacattga tttttcaatt aaaggattta gattatccat attttctaca actaaatcta
    10081 gaatttgtat agtaaatttg gcaataaagt atacatttat ttctcttttt tgtacatgaa
    10141 taatgtatat aaactgatga attagagcat ccaataagaa aactaaatca aatataattt
    10201 tttctatttt atcaccatag ttatcaaata agcttagttt gtattcattc aataagttag
    10261 ctcttgattt tgtttgcaat ttacttgtag ccttacgttg atcttcagaa aagttttctc
    10321 ttatataggt atttatggta gttctagaaa aaatattttt ccatacagca attatctttc
    10381 tgtttaactt ttctgatgat ggaatgtcat tattttcgtt tatggaatgt ataatttcta
    10441 aaaacttttc atcataataa ttgattattt cgcagataaa actttcctta gtttcaaaat
    10501 gcttgtaaaa agtagcttta gacattttac actcttttac aacatccgat attgaagtat
    10561 tttgaaaacc tttttggtca aaaatttttt gtgcaatagt tataatgagc ctttgttttt
    10621 ctgtcacttt attatctcct ttcacgtaaa aacgtttagt actatatagt acctacaagt
    10681 tttaataaat atattataca tcatttggaa aaaaaatcaa tatatagact gtaatatgaa
    10741 atttttgaaa aatttgttgt tatttttagt cgtataaaaa agaaacttaa gagtttctta
    10801 agaattgttt aaagaagttg caataaatta gtggtatgat tatagtatga aagagaatgt
    10861 cttgaaattt ttctgtatca aattccaatt atggaggtgt agtatatgaa aaagaaaatt
    10921 tgtgtagcaa taatttttgc tctatttata gtttttgtag aaatgtttat tgatagctct
    10981 agcgaaggaa gtaaaattat gacagctgaa ttaagtaaat acaggaaagg cgtaaatgta
    11041 ttatcaataa acaatattat agtagcgaat aaaaaatata gtttgcccaa agattattct
    11101 cctcaggaaa gcagtgaagc gagagatgct ttttataaaa tgaataaaga tgctcaaaag
    11161 tcaggattaa atttaaaagc ttttagtaca tatagaagtt atgaatatca agatagatta
    11221 tttaaatcat atgtaaaaga acatggagaa aaagaagcaa atagattttc agctaaacct
    11281 ggagagagtg agcatcaaac tggacttgct tttgatattg gaggagatga ccagtcttgt
    11341 tgggcaaata aaaagttcaa caatacaaaa gaagctaagt ggttgtatga aaatgcatat
    11401 aaatatggtt ttatacttag atatccagaa ggtaaagaga atataacagg atatatgtat
    11461 gaatcttggc actatagata tgttggaact gaacatagca aaaactttgc aatgaataat
    11521 ttgactttag aagaatattt acatataaat taagagatgg tttgttaaaa ttaggttaaa
    11581 ataaaaaata acctagacta ttagctgtgt aaagtgatat aatgtaaata caatttaaga
    11641 taactactcg aaggggagta gcttacacga aagtggtaat taatcgtcaa gacagtagaa
    11701 atactcggtt aattagcaag ggattccttg atagcaagac cttcaaaata agcattaggt
    11761 atgtttgttt tggggtcttt ttttattcaa ggaattttta tttaaaaaaa tttaaatttc
    11821 aagtatacat aagagccccc aaacataaaa taaatttatt gaagaggagg gcaacaaatg
    11881 tcttacaaaa gtacttatca agaagtaatt aaaaatttag actcaagttt atctggtttg
    11941 agtaaagaaa gagcagaaga gttgttggaa aaaaatggag ctaatgaatt aaaagaagca
    12001 gataaggttc ctacttataa gcttttccta gaaagtttta aagacccatt agtaataatt
    12061 ctattgatag ctgctttagt acaaatattt ttaggtgaaa cagtggagtc tataataatt
    12121 tttgcagtta ttattataaa ctctgttctg ggtgttgtac aaacaaaaaa agcagaaagt
    12181 tcattagaaa gtttgaaaaa tttatctgca ccaaacgcaa aggtaataag agacaataaa
    12241 aaaatgacaa ttccagcaaa aaatctagta gttggagata ttgtattctt agaagctggc
    12301 gattacatac cagcagatgg aaggcttata gaagcacaat ctctcaaggt tgtagaaggg
    12361 atgttaactg gagaatcaga accagtttta aagcatacag aaaaaataag tgaagatgta
    12421 agtttaggtg accagaaaaa tatggtattt agtggtgctg tagttgttta tggtagaggt
    12481 tcttttgtag tgactggaac aggtatggat actgagatgg gtaaaatagc tgggctttta
    12541 gaaagtgctg aaaataaact tacaccattg caacaaaaaa tagaggattt tagtaaaaaa
    12601 cttggtgtag gtattgtaat acttgctctt ttaatattta taattcaagt agcaagaaat
    12661 tactttatgg ctggaaatgg agaaatgaca caaattattt tagattcatt catgttctct
    12721 gtagcagtag cagtagcagc tataccagaa gctctatcat caatagtcac tatagtattg
    12781 gctgttggaa caaatagtat ggcaaaaaaa caagccataa taagaaaatt accagcagta
    12841 gaaactttag gttcaacaag tgtaatatgt actgataaaa caggtactct tacacaaaat
    12901 aaaatgacag tagttgatta ttatatgtat ggaactaata atgatgagtt agataaagaa
    12961 aaagtaaact attcttatca tgctaaatta ttgactatgg tttctacatt gtgtaatgac
    13021 tctcatataa ctagtgatgg taaagaagtt ggtgacccaa cagaagtggc tttaataaat
    13081 tattcaagta aaaatgattt agattatgat aaattaagaa gtaagtatat cagaataaat
    13141 gaaataccat ttgactcaga cagaaagctt atgtctactg taaatagtat atatggagat
    13201 tatataatgt ttacaaaagg tgctccagat attgtgttta gtagatgtaa atatgctttg
    13261 aaaaatggtt caaaagtaga tataacagat gagataatag aagaatataa acataaaaat
    13321 gaagagtttt caaatagagc acttagagta ttagcttttg caataaaaga tgtcccagaa
    13381 gaagatttta taccttcaat tgatgacgaa catgacatga cattggttgg aataatggca
    13441 atgatagacc caccaagaga agaagtaatg gatgcagtaa aagaggcaaa gagtgctggt
    13501 ataaaaactg ttatgataac tggtgaccat aaaacaacag cagcagcaat tgcaaaagag
    13561 attggtataa tggaagaagg agacttggct cttactggaa aagagcttga tgctttgagt
    13621 gaagaacaac tatatgaaaa actagaaaat ataagtgtat atgccagagt ctcgccagaa
    13681 aataaaattc gtatagtaaa agcatggcaa cataagaata atataacagc aatgactggt
    13741 gatggtgtta atgatgcacc tgcattaaaa caagcagata taggaatcgg tatgggaagt
    13801 ggtactgatg tagcaaaaga tgcttctgct atggtattgg ttgatgataa ctttgcaagt
    13861 atagtaaatg ctgttgaagt tggtagaaca gtatacagta atataataaa atcaattact
    13921 tatctatttg caggaaactt aggagctata gtatccatag tatttgcagt gtttgcaggt
    13981 tggtcaaatc catttacagc tttacaactt ttgtttataa acttagtaaa tgactcttta
    14041 ccagcaattg cattagggtt tgaaaagtca gaaaaaaata taatgaataa acctcctaga
    14101 cacccagatg aaagtatact agcaggagga acattgaagg cagttgctat aagaggttgt
    14161 ataataggtg tagttacaat aattgcacaa tatataggat tacaagtatc tccagaactt
    14221 ggagtagcaa tggcattttc aacattgata ttagctagaa taatgcaaac attacctgca
    14281 cgttctaata atcaaacagt aataaaatta ggttttttca gcaataaata cgttatagga
    14341 gcagttttag tctgtcttgg gctttactct ttaacactaa taccagtgct aagaggaata
    14401 ttctctatac caacaacgtt tggattgtac cagttgggga tttgcctagg gttagcatta
    14461 atttcatcaa tattaatgga acttaacaaa ttaataaata gaagtgaagt aaaataatca
    14521 aaaaattaaa gggcatattg attttaacaa tatgcctttt ataaatagtc taatttattc
    14581 tatattatcg attatttgga atgcttttat aacttcaggt aattcttttt cttcaggcat
    14641 tctaaatctt atgaaatttt tatcaagtcc agtaaaatca cttccagata taactcttat
    14701 ttttaattta gcaaactctt gttgtaaatc tatgtccttg tttttatgtt caactgtcat
    14761 aattgataca gtatcactag tttcagctat attaaggttt ttccatggaa ttagtaattg
    14821 attttttata tcttttgttt tttcttttaa ttcttctata aattgaacat catctaataa
    14881 atttgctgca atactacgag atatttcaga cacttcgtaa ggagtagaaa tctttttaat
    14941 agggctaaca agttgttctg gaagaactgc atatcctgct cttagtcctg ctaaaccaaa
    15001 tccttttgaa aatgttttta aagcaattac attatcataa ttatttagaa gcttgacagc
    15061 tgaattttct tttggcatgt attcaccata agcttcatct accataactg ctatatcata
    15121 tttagctgct tcctttacta tattttcaat tgatgataaa ggtataattt gtcctgtagg
    15181 attgtttgga ttgtctatgt aaattacttt atattctgga tttatttttt caataaattc
    15241 tttttcatta aacttgaaat tatcctcttt ctttaaaaga acataatcat aagttgcacc
    15301 atgcattttt atatctgtct catattctga gaactgaggt gaatatccta aaactttatc
    15361 tcccttttca ataaatagtc tatttaaaag gtaaataaca tgtatagaac catctgccaa
    15421 acaaattctg tcagtatcta atgctataaa atctttccaa taatcgacta tattatcttt
    15481 taaagcaatt gaatgaggat atcctcttat catatcaaat tttaaagcat taaaagcctc
    15541 tacagctttg tttgagtaag acacggtatt tataccttca ccacagtcta tctcgaatac
    15601 atcttctgaa tgtccagatt ctattgcata actttttttc aactgcattt caatagcttt
    15661 gttaattttt agtttcatac tttatcactc cttatttagt caataataaa tgttataaaa
    15721 gttgctagat ttaaaatatt atgaaaatat ataatagtaa aaaatgaata taaatattat
    15781 aatagctcac tttatttaat atgattatat atcatatatt gtaaaatttc tagcattata
    15841 agactataaa ttgaaaatat tcagaaaaat actacaagaa acgatttatt ttgctcttaa
    15901 aataagttaa atgaatgtta ttaattttgt aaattgaaat agtttaagta taaagttatg
    15961 atataatcta ataagggtaa ttctttagat tatattaagg aaatataggt atacaataaa
    16021 aagttatgga gttggattat gggatataaa ttaattgtaa cagatatgga tggaacttta
    16081 ttaggcaata atcataaagt tacagatgaa aataaaactg cactacaaaa agttataaaa
    16141 agcggtatta atgtaacttt agcaacagga agagccttcg attcagctaa atgcaatgta
    16201 gattttctta aagaggacat gccaataata gcttgtaatg gttcattaat aagagagcaa
    16261 aatggaaata taatatattc aaataagatt gatacaagaa catgtttaaa cattttagat
    16321 gtattagata aatacgatat ttactaccaa tgtaatagta tagattctat gctttcgaaa
    16381 aaaatagaag gacgtgaaga tagattaagt gtatttttag gctctgaaac agaagtaatt
    16441 gtaaaagatg atttgagaga agaaatcttt aaaaaagata tactaaaatt tgtaatcata
    16501 gaagaaaaaa atccatctat tttggatgaa ataagaaaag aattgagaaa agttcaagga
    16561 ataaagataa cttcttcatg gccaaacaat attgaagtca tgaatgaagg tgttgataaa
    16621 ggtaatgcag ttaaaatttt agctgaaaaa atgaatatag acagagaaga tataattgca
    16681 tttggagaca attacaatga catagaaatg ataaagtttg ctggtcttgg ggtagctatg
    16741 ggaaatgcag aagaattgat taaacaagaa gctgattatg ttacagatac aaatcaagac
    16801 agtggagttg caaaggcaat ttataaattc ctagagttaa aagaatcact tagctcttaa
    16861 aacagtatat aataggaaaa aataggttga ctattttgta gatagtaatt ataatacaaa
    16921 tagataaaac ataaaaattt agattcagtg aaaaagagag tagatataga gaaaatctca
    16981 gcgaattggg ggatggtgtg agcctaatga taacacttta tattgaaaag aactttggag
    17041 aatactactt gaaattcagt atggtagtag gtaatctcgc cttaagagaa tagagtgggt
    17101 aaacattgtt taccaactag agtggtaaca cggaatattt cgtctcttgg tctttttgac
    17161 caagagattt tttagtttca ttgagttaca agacttataa ttaaaataca aaaaattaaa
    17221 atatgaggtg aaagttatga aattatgggg cggacgcttt agaaaagcgg aaaatcaact
    17281 tatggaagaa tttaataaat cttttggcta tgattgtgta ctgtacaaaa aagatatcga
    17341 aggaagtgta gcacatgttc atatgcaagt aaaatgtgga cttttaacag aagaagaagg
    17401 aaagtctata acagaaggtt taaaagggat acttgaagat gtagaaaatg gaaagttagt
    17461 attggatgga gagtatgaag atatacatag ttttactgag ataaatttaa ttcaaagaat
    17521 tggagatgtt ggcaagaagc ttcatacagc acgtagtaga aatgaccaag ttgcagttga
    17581 tatgagattg tatgctaaag aaaaagcaaa tgatttggtg ggtttaatat ctgaatttaa
    17641 agctactata aaagatgttg ctgacaaaaa cccagtgatg atgccaggct atactcatct
    17701 tcaaagagct caagtagtga catttaagca tcacttaatg gcatattata gtatgtttga
    17761 tagagatgag aaaagaataa aaaatgctat agaaatatta gatgaatcac ctttaggctg
    17821 tggagcttta gcaggaacta cgcatgatat agatagaagt ataacttgtg aacaattagg
    17881 atttaaaaaa gtagtagata attttatgga tggagtaagt gatagagatt atttactaga
    17941 gctaatgagt gatttttcaa ttataatgat gcacttaagt agattaagtg aagagttgat
    18001 actttggagt tctcaagaat ttggatttgt tgagatagat gatttatata caactggaag
    18061 tagtataatg cctcagaaga aaaatccaga tggtgcagag cttataagag gtaagactgg
    18121 cagagtatat ggaaacttat ttggtctttt tacagtaatg aaaggaatac cattagcata
    18181 taataaagac atgcaagaag ataaagaagg ttttttcgat agtgtacata ctcttgaaat
    18241 gtgtatacaa ataatggata gaatgatagc cacactaaag gtaaatgagg ataaaatgaa
    18301 acaagcagta aaaaatggtt ttttaaatgc aacagaagtt gcggattatt tggttaaaaa
    18361 taatgttgct tttagagatg cacatggtat agtaggaagt atcgttatat attgtgaaga
    18421 taataaaaaa gcaatagaag atttaacatt agaagaatta cataagtttt cagatgcttt
    18481 taaggaagat atttatgatt ttatcgacta tgagagtata ttaaataagg gaataaaaaa
    18541 gaatttaaaa taatgtattt atttttaaaa gctgtaaatt tgaatgttat catttaaatt
    18601 tacagctttt tattgtgtaa gattttatta tataaaagta agaaacttaa aaggagtagt
    18661 atttaaaata aatacaaata aaaaaattat tattaaaatg ataattaata tcaataagta
    18721 ttgacaaaat tatttctaaa tactattata tataatataa ataataatga aaatcaatat
    18781 caaataaatg ggaggaaatc taatgaactt attagtgatt ggtggtcatg aaagaatgga
    18841 aaaagattat atggttatgg ccaagaaaaa aggttataag acaaaggtat atactaccat
    18901 gtcatctaaa ttaaataatt ctataggaag accagatgca gttgtcatac ttacatcaac
    18961 tgtttcacat aagatgtcta gaacggttga gtctcaagct aaaaaacaag atatattaat
    19021 cgtaaggcat aaaaatagta gtaaggtagc atttaatgaa tgtctagata tggttgatga
    19081 atgtctagga aattgttcaa aatgtaagct taaagacaaa caaaaacaaa aaaatatata
    19141 ggtataaaaa atacataaac ataaaattaa aagtactgag ataatagtta taattattat
    19201 ctcagtactt ttagatttat aaggataagt atattataaa ttttttatta taatttccaa
    19261 ctacttgtta ctttttcata ttttttttac ttctagcttt ttttcttttt ttcttcttta
    19321 tatttgaagc tattataaat aaaactaaaa gcactagaat acctgcaata atcttaacaa
    19381 aagtcattaa aatattattt ccagtaaaaa atggaagact gctatcaaga ttattttttg
    19441 caattaagtc tatactgttt tctagtttac cattattata tacatttaaa gtaccaacct
    19501 tagccccttt ttttataggc aaatcaattt tatttaactc tgttttggta tcataattgc
    19561 cttgagattc atctttttct aagaatatcc tataactatt ttttggttca taaatcaatt
    19621 catgttgttt tgtaaacaat acttttttag tatctgtgta tttttcttta tcaacaatag
    19681 tagcacactt aaagttatca aatccataat caatcagaat acgtgagtct aaatataaat
    19741 cagcattagt tgaattaaat acagcaacga taactcttct gccatctttt acagcactcg
    19801 ataaaagaca tttaccagca gcatcagtat atccagtttt tataccatca actatatcat
    19861 attttatatt tataggttga cctttgtatg taatcttatc atgtgatgtc aaaaacttat
    19921 tagtgtttac aaagtatctc tcataaggat atgcttttgt agcttcaaat ttaagtgact
    19981 tagtttttac aatttgtcta aaagtatcat tattcatagc ttctctagct atgagagcca
    20041 tatcatgagc tgttgtgtag tgatttgggt ctggtaatcc atgaggatta ttaaaatgag
    20101 tattagtagc tccaattttt tttgcctcag agttcatgag gtcaataaat ttttgtacat
    20161 tgccaccacc aacatatcta gctaatacaa aagcagcatc attagcagaa tgaaccaaaa
    20221 gagcatctag taactgcttt acagtaaagg attccccctc ttttagatac atactagagc
    20281 catctatttg aggtaaatct ttaatttcta ttacttgatt taaatcttta acctccttta
    20341 gaactaaaca agctgtccat actttagttg ttgaagctgg ataaagctta gaatttccat
    20401 ccttattata tagtattttg ccagactcat agtccattaa aactgcatgt ttagcaacta
    20461 tagctggttc attatctgca aaagagatat tagagcttcc taaaaatgaa gtaaatatca
    20521 ataaacagat taataaaagt gataaatttc ttttcattgt gagcctccaa attttaaatt
    20581 catcttttag tatagcatat atttgtcaat aattaaaaga aaggagtgat taatatatga
    20641 aaaaaaaggt aaaatttatt tcgttttttg ttttatttat tttaataata tcatcaataa
    20701 tcgtttataa atcgcttatt ttcaaagatg atatttatgt tgtaagtaaa aaaaatttac
    20761 ctaatgaaaa aacacatgtt gtagagaatg aaattaaagg tgaagataat aatcacaata
    20821 aagtaactaa agacatagat aaaaattttc aaaataataa aataactata tacataagcg
    20881 gagcagtaaa tagacctgga attgtaacta tagagtcaga caagagactt tatgatgctg
    20941 tagaattact aggaggaacg acaaaagaag cagatttaaa tggagtcaat ctatcagtaa
    21001 gattagaaga tgaacaacat tacataatac ctaaaatagg tgaagcaaca tctgttacaa
    21061 gtaatgatga ttccaataaa ccaaatcaga agaataagtc aagaggtgag cctaaaaata
    21121 aatccaataa aaatatatct aacgaatcaa aagtaaatat aaatgtagcg actatagaag
    21181 agttggattc tctacctggg gttggagaag ctacagccaa taaaatttta caacacagag
    21241 aagaaaatgg acagtttagt tcaattgagg aaataaaaaa tgtaaatggt attggagata
    21301 aaaagtatga aaatataaaa gatttaattt gtgtagacta aaatataata caaaacttac
    21361 atatagatat gttattataa atatgtatgt atatgtgtgt acatgtggaa atttagtaaa
    21421 ggaggcactt ttatgaaaaa agaacaaaaa aaacttacag agatgacaac agcaggtggt
    21481 tgagccgcta aaatagggcc agaggttctg gcatcagttt tatctcaatt gcctaaaaat
    21541 gataatatag aaaatttatt agtaggacta gatacagcag atgatgctgc agtttataaa
    21601 ttaaatgatg atatggcact tatccaaact ttagacttct ttacaccaat ggtagatgac
    21661 ccatacgtat ttggtcaaat tgctgcatca aattcactat cagatgtata tgctatggga
    21721 ggcaaacctt tggttgctat gaatattgtt tgttttccat catgccatga tatggatgta
    21781 cttgcagaaa tattaaaagg tgggtttgat aaagtgaaag aaagtggagc acttttggtt
    21841 ggagggcata ctgtagatga caaagagcct aaatatggtc tttcagtttc tgggattgta
    21901 agtccaaata aagttttatc aaatgctact gcaaaacctg gtgataagtt aattataaca
    21961 aaaccaattg gagtgggtgt attaaataca gccatgaaag aaggtatggt agaacaacat
    22021 atagcagata aagtaataga aataatgata catttaaata aatatgcagc aatgagtttt
    22081 gagaaattta atgtaaattc ggttacagat ataactggtt ttggtctact tggtcatact
    22141 ttagaaatgg ccaaagcttc tgaagtaagt attgaaattg aatcaaaaca tgtaccaatt
    22201 attgaaggtg caatagaaat ggcacaaatg ggaattatac ctgctggtat gtataaaaat
    22261 atgcattatg tgtctaaaga tgtagaagtt gtaggaaata tagaagttgc agttcaagat
    22321 attttatacg acccacaaac atcaggaggg ttgttaattt cagtaaaaga agaacttgca
    22381 gaggaacttg taaaagatat gaaattaaat ggagcaatag aagctaaaat tataggttct
    22441 gtagttccaa aaggggaaaa atatattaca gttttataaa atattataga gaaagagtga
    22501 ttgttttgag caaaagagaa ttgtttgcaa tgttgccttc agttgatgaa gtattaagtg
    22561 ataatagaat tgtagaaata ataaatgaat atcctagaag tttagtttta gaatctgtga
    22621 gagaagtaat agatttaaaa agacaattta tattaagatt aaaagaagat gtatcaaact
    22681 ctgtaacaat agagtttggt gaaataatag aatctgcaat agagagagtt aagttaaatt
    22741 actcattatc tttaaaaaaa gttataaatg caactggtac agttattcat acaaatttag
    22801 gaaggtcttt acttagtgaa gatataaaag atgaattatg gtgtgctgct tcaaggtatt
    22861 caaacttaga atacgatttg gataatggag aaagaggttc aagatactct catttaacta
    22921 gtacaataaa aagacttact ggagcagaag atgtactagt tgtaaataat aatgcagcgg
    22981 cagtacttct tgtacttagc acaatggcta aaggaggaga agcaattgta tctcgtggag
    23041 aattagttga agtaggtggt tcatttagga ttccaagtat aatggctctt agtggtgcag
    23101 aattagttga agttggttca actaataaaa ctcatttgaa agattacaag gaggctatta
    23161 cagaagatac aaatgtattg atgaaggttc atacaagtaa ttatagaata atgggattca
    23221 cagagagtgt ttctatagaa gaattggtta atttaggtaa aaaatataaa ctacctgtaa
    23281 tagaagactt aggaagtgga gtttttatag atttatcaaa atatggttta tcttatgaac
    23341 caactgtatt ggattctatt cgacaaggtg cagatgtagt aacttttagt ggagataaga
    23401 tgcttggagg tccacaagca ggtattatag ttgggaaaaa agagtatata gaaaaaatga
    23461 agaaaaatca acttactaga gcacttagag ttgataagct tacaatatgt gctcttgaag
    23521 caacattgag aatgtattta gatgagacaa aagctataga aaatatacct actttaaaaa
    23581 tgttgacata taaaattgaa gaattagaag taaaagcaaa taaactattt gaaaaaataa
    23641 ctgctttaaa cttaaatgca aacataaata tagaagatgg attttcacag gtgggaggag
    23701 ggtctatgcc tcttgaaact ataagtacaa aggtaatatc aataactcct gaacatatga
    23761 atgtttcatc tttagaaaaa aaactaagac ttagtgaagc acatataata gccagagtgt
    23821 atgataataa atatgtacta gatgtaagaa ctatatttga tgatgaattt gatgtaatag
    23881 ttgcggaatt gagaaaagca tttaattaaa taaatttgag ctaataaata ttaaatttag
    23941 aagtataagt atgaagtttt gattaaaaaa tagctacaca cacttgtgac tttagtcata
    24001 gcaggtttag agggggcaaa aaatgaaaaa tgtagtaatt ggaacagcag gtcatattga
    24061 ccacggaaaa actactctta taaaagcatt gactggaaga gagactgata cattagatga
    24121 agaaaaaaag agaggtattt caataaactt aggatttact tattttgatt taccaaacaa
    24181 tagaagagct ggaattgttg atgtcccagg acacgaaaaa ttcataaaaa acatgttagc
    24241 tggagcatca ggaattgata tagttttact tgttgtagca gcagatgaag gggttatgcc
    24301 acagacagtt gagcatttag atattctaag ctttttaaat atcaaaaatg gaatagtggt
    24361 tctaactaag tctgatactg tagatgatga atttagagag ctagtaaaag aagatatttg
    24421 tgaaaaaata aaaggaactt ttcttgaaga tgctgaaata attgaagttg attctatatc
    24481 taaaagaggt atagacactc ttattgaaaa aatagataaa atgagtgatg atatagaaga
    24541 taaaaatgaa aactctccag caagacttaa tatagacaga gtattttcaa taaaagggtt
    24601 tggtactgta ataacaggca ctttaataga aggaaagata agtatagaag atgatttagt
    24661 tatatatcca caggtattaa aaacaaaaat aagaagtata caagttcatg gagaaaataa
    24721 agatacagct tatgcaggtc aaagaacagc aatcaatata tcaaatgtaa aagtggatga
    24781 tataaaaaga ggagatgttt tagctgcacc aaactcatta gaggaatcaa tgatgttaga
    24841 tgtaaaatta tcattggtaa atcatttaga taaaggatta aagcactggg atagattaag
    24901 attgtatcat ggaactagag agatactttg tagagcagtt ccactagata aagaattaat
    24961 tgaaagtgga gaaagtggct atgttcagtt gagacttgaa gaaagcatag tatctaagaa
    25021 aggtgatacg tttgtagtga gacgttattc tccaatggaa actataggtg gaggtgtaat
    25081 aattgaccca tctcctaaaa aacataagaa atttgatgaa aaagttatag aagcattaaa
    25141 aataaaagaa aaaggcgaac taaaagatat aatagaagag tacttaaaaa ggaatttaaa
    25201 aaattatcca aatataaaag aaataatgag ctatagtggt gctcatgaag aagatgtaaa
    25261 aagagcgctt gaagcactta tatcagaaga taaagtattt attataggaa atatgtatat
    25321 gcatataaat caatacaata aattaaaaga aaatacaata aagcttttaa gtgagtacca
    25381 taagaagtat aggcttagaa aagggatact aaaagaagaa gtaaggtcta agatagagag
    25441 taattttaag actagggaga tggatatttt attagaaaaa ttgtctacag aaaatgctat
    25501 aaaaatagaa aataatatag tatctctatt agattttgag gttattttaa atgataagca
    25561 aaaagaaata gcaaaaaaaa tagaaaaaag attaaaatca tgtggagttt cttctatact
    25621 gacaatagat gaagtttctg aaggaaatca taactatgct gaagtattgg agtcaatgat
    25681 aggtaataaa gtagagaaat tagatgattt gtatataatg gacaaagata tttatgaaaa
    25741 tgcaaagaac attttgataa attatataaa agaaaataaa gaaataacat taggagaata
    25801 cagagatttg attgattcta gcagaaagaa ttgcatgatt atattggaga acttcgatag
    25861 aaacaaaata actaaaagag tagaaaacaa aagaattttg ttttagcaga aaatgtctgt
    25921 ttttgcttta aggtataaag aaggaattat aatgtcgagt atcgtataat taattagtat
    25981 aaaatattaa ttaagaggaa gtgtaaagta ttgaagaata taatacctga tgtaaaacca
    26041 gatataaaag aaagagaaga catgagcctt ttatttataa taatgggctc agtactttta
    26101 ttatttatta taaaagatat agagaaatat gaaactttat tacatgccat atatacgata
    26161 tttttagtag ctacaggagt aattatattt aatactacaa aatttaaagt agattcattt
    26221 tctacatttt taggattaat ttttatagct actggagtat tggagtgtat atatttattt
    26281 aattccttgg ggattaaaac taagtctata atggagatta acatcacaat atcagcaata
    26341 acagatttat ttcctatact gggtgtatac ttaagtttta aatttgttaa ggataacaaa
    26401 caaatttatt caagtataat tttatttata gcaactgcta cattaacaat aacatcttta
    26461 ttcataatat caggaatttg tgactatctg ggaaatggta aatcacaata tgctttagga
    26521 gttataatat ctatattcat aataattatt tctatcatta gtggaattga attaaattca
    26581 agttcaaata aaggtaaatg ggaatatgat gaaaaaaaga tttttaacag aataatagta
    26641 ataataattt tatcaagagt tccaaatcta ttgcatatag ttattgataa tagaaatgta
    26701 gagaggatat tatcacagat aataataaat gtagccttat attatttata taattacata
    26761 gtatctaaga atattaagaa aacagcactg gaattgcatg atacgaatga agaattaaca
    26821 aaaaaaacgg aaagtttaaa agaaaagaat aaaaaattaa tctatgagac agaaaagata
    26881 gaggaactta agggaatact tatgaaaaga gaatctaggc tacaatctac attagatgta
    26941 gcagtaaata gcatagtagt gtttagcaaa gatggagaaa ttacatatgc aaataagagc
    27001 tttagaaata cttttggaga ctataaagaa caagataaat tgactgataa aataaaaaac
    27061 ttcaatgatt tgatagaaag cattcattat gtgtttgttc atgagaagaa tgcagagaaa
    27121 cttattagta caagcgataa taaagtttat caagctatat ttgcaccttt aattattgct
    27181 tcacaaacag aaggagtatt gtgtgtacta gaagataaga ctaagaaaaa ggagtacgaa
    27241 cgcaaactta ttgaagcaaa taagagaagt aaagattttt tagaaagtat tggagatggc
    27301 atagtagtgc ttgaaggtaa taacaaaata tatgttaata atgcatgtag ggaaattttt
    27361 aaaaataatt tagagagtat tgatttttca ttagtatgta aaagtgaaga aagtatagaa
    27421 aaaagatatg taatagatgg tgaagtaaag tatgtagaga tgagtttttc tcagtatact
    27481 aatgctggta ctaataaaac tattattgta atacgtgata caacctctcg aaaaatatct
    27541 caaataaaac ttgaggaaag tcaatcatca tattcaagat ttatagatat attacctgat
    27601 ggcatatgct tattaaaaga agatttaagt ataaactatg caaataagtc gtttttagat
    27661 atgctagctt ttacaaacat agatgatata aaagattcta atattaaact attaatgaat
    27721 gcgaatactg aagaaaaaat gaaatttacg gataatatgg ctaaagtttt aaatgaaaat
    27781 agaagtatac ttttactgga atatgaattg ataaatagtt atgatgatat agtagaagta
    27841 gaattaagtg cattaccttt tgctatatac aatactagat acataatgct tattataaaa
    27901 gatttagtac ataagaaata ttccgagcaa gcagaaaaag aactgcttga aagatttaaa
    27961 acagataaaa tcaaaacgga gttttttgca aatatgtctc atgaattaaa aactccacta
    28021 aatgttatat ctagttcaaa tcaactggta gattctttct atagaaatga aaagataaaa
    28081 gattacaata acaatattaa atctcatgtg gatttagtta gacaaagttc ttataggctt
    28141 caaagattaa taaataacat tatagattta acaaagatgg agtctgggtt ctatacacta
    28201 aaacttgcga aatacaatat tgtatctgta atagaagact tatttatgaa tatagaagag
    28261 tatgcactta gaaaagacat aaaaattctt tttgatacag accttgaaga aattaatgtt
    28321 tatatagaca aggttgaaat tgagagaatt atgttgaatc tattgtcaaa ctgtattaag
    28381 tttactgata atggaggctg gatatatgta agtattcatt ataaaataga taaagtaatc
    28441 ataagtgtaa aagacactgg agttggaata ccacaagata aattagaatt gatttttgaa
    28501 gaattttcac aagttgataa gactttatcc agaaatactg aaggaagtgg aatagggctt
    28561 gctatagtta agaatctagt aagtcttcat ggtggagata tagaagtagt aagtgaagtg
    28621 aataaaggca cagagttctt aatttcactt ccaatgaagg gatttagtag tgaacattac
    28681 acagaagata agagaatata taatattcaa gaaaaaataa aaatagaatt ttctgatata
    28741 tactattaaa aatgattata agcaaaaata aaataaaaat actatttgtt taaatattta
    28801 agttgtaaga aataggctat cataaggtaa attattatga tagcctattt ttagctaggt
    28861 tttatatcta tatgtgagaa catataatct ctaaattacc ttcaaaacta aaatctccaa
    28921 agtcgtttgg cagtataaaa tgcataccct tttttaaatt atattctaca gaattgtgta
    28981 taagttttcc atttccatcc aacacactgt ataaagaaaa aggtgtattg tgtgtaaaat
    29041 tacattttcc aaaaacatct aatttataaa cactaaaaaa ttcgtttgac acaaatgttg
    29101 tgcatttaaa gtctgatgtt gatacgattt tatagtcagt atcgaaattt atatgaggaa
    29161 cattcgtaac atctattgat ttttgaacat gaagttcacg cttattacct gaattgtcag
    29221 ttctatcata atcatagact ctataagtag tatctgagtt ttgttgagtt tctaaaatca
    29281 atgttccttt gcatatagca tgtatagtac cacttggaac atagaaaaag tctccctttt
    29341 ttatattaac ctttctaagt agtttgtccc attcattatt atttaccata tttacaaatt
    29401 ctttatgaga ttttgcatta tgacctatta taatttctgc atcatcagaa caatctatta
    29461 cataccaaca ctctgtctta cctaactctc cattttcatt tttcttagca tattcatcat
    29521 ttggatggac ttgaactgat aaattatcat ttgcatccaa tatttttgta agtaaaggaa
    29581 acttatcacc aggtgtgttt ccaaataatt ctctattttt attccacaat tcagatagtt
    29641 ttttaccttt atattttcca ttttctatta agcaatctcc atttttatga gagcttatag
    29701 cccaacattc accagttgtt ggcgaatcta tttcataatt aaatttatct ttaagtgcag
    29761 taccacccca tattctatcc ataaaaatag gttttaaaaa taatggttcc ataatcctgt
    29821 tcctcctatg atattaaatt tatcctacaa ataattatat ataaatagat tataaaatca
    29881 atagtaaaaa agttttgtcc cttgaaatga cataaagtat aaggagttat taaataagat
    29941 aaactatgat atataatata aagttctaaa ttggagtgat aattatggag ttgtttaagg
    30001 cagaaagcaa aaaatatgaa aaagaatttt taaaattatt ggagcaatgg gttagtatac
    30061 cttcatttta tgatagaaaa actgtatcta aagatatgcc ttttggaaaa ggagtatatg
    30121 atgcattaaa ctggtttgaa aatctaggta gagaaaacaa tttcaaagta aaaaatatag
    30181 ataatcatgc tgttcaaatt gaatatggaa atggtaaaga atatgtagat atatttggac
    30241 attgtgatgt tgtaaatcca ggtgaaggat gggatagtga accatttaaa ctaaatatta
    30301 taggtgataa attagttgct agaggtgtat ctgataataa aggacctatg atagtgaatt
    30361 ttttagcact aaaaatgata aaggatttag atattaattt aaaaagaaag gttagattaa
    30421 tagctggagg aaatgaagag agtggattta aatgtataaa gcattattat agcaaagagc
    30481 catatggtgt atgtggattt actccagatg ctaaatttcc tgtattaaat ggagaaaaag
    30541 gtggagcaat aataaagtta atttcaaata tagacgataa atctttatat ataagtggtg
    30601 gaatagagtt taatacaata ccagataaag tttatataaa gaatgtagaa aaattgggta
    30661 aagataatat atgttttgat attaacaata tatcgataaa ttatgataat ggcaattata
    30721 ttgtgtatgg aaaaggtggt cattcatcta aacccgaaaa atcaataaat cctatattag
    30781 ctacaattaa acttttgtca gaaaatattg atgaaaaatg gacaaaagat ttatataagt
    30841 tgataaatca agataatata aatggaaact tatttggttt aaatattgag gggaaatgtg
    30901 ggattttatc aatagtgcca acaataataa atatagtaga tggaaaatta gaagtagttt
    30961 taagcgttag atatccagaa atattaacca ttgaagatat aataaaaaaa tttaatttgt
    31021 atatggagca aaataatatt aataaatttg agcttattgg ggaaaattta aagcaagcaa
    31081 attatataga tagaaattca aaacttgtaa gaagtttgca tgatatatat ataaagtatt
    31141 ctggagattt aaaaaatgat gttagagtaa ctagtgcagg aagttatgct tctgaaatga
    31201 ataattcagt aatatttggt tgtgaatttc ctgatggtag ctttggcaat gtccatagtg
    31261 cgaatgaatt tgctagctta gatagattta taactgcaat aggtatatat gcagaggcaa
    31321 taattacatt atgtaataaa atataaatac aaaatgtccc ttatatagac atattatata
    31381 tacaattaaa attttacttg atatataatt gaaatcaaag agaaggtgat acaatgataa
    31441 ctaagaaaca tgcaataata gtaaagagtt taagcaataa agatggatat atgacatcaa
    31501 acgaattagc tatcaaattg gatgtgtcta ctaaaactat taaaagatat atagcagatt
    31561 taaatagtgt tttaagcaag tatgatttgg taatagcttc ttctagaggt ataggataca
    31621 agttaagcgg ttctaaaaac aatatagcca gagctgttaa agaagcaaat aaatatattg
    31681 atggtttttt agatgactct gaagagtcaa gaatgtcaaa tataatatgt atgcttatta
    31741 atagaaatta tatgagtata gaagcaatgg cagaagaatt aaatctaagt atagccgcta
    31801 taaataaatt gtctagtaag cttaaaagaa aacttgaaaa gtatgactta gttataaaat
    31861 ctaaacctta ctatggaagc tatatacatg gtgaagaaat taatataagg caattaatta
    31921 ctgactatgc aataaaatta gatgaaaaaa gtaaagtgaa ggtgttttta gatgacatta
    31981 gtgaaaacga tatatactgt atagaaagta ttttagaaaa gcacttaaga gaaaaagata
    32041 caataatttc agataaagat tttaatcttt tgctttcaaa aataattgtt tctgtattta
    32101 ggagtaagag aggtcatagt aacaatataa acttaatgga tacaagttat agatttcata
    32161 actactactt tatagaaaat ctaatgaaag aaatatctga taaaattgga tttaaactta
    32221 ttgaagatga agtaatttat atttcaaatt attctggtgt aatagcttat aaaggtacac
    32281 aaggaagaaa aaacacaagt gaaattgagg aacgaataag tagtgttata agtagtgcac
    32341 ttcaagatat attccttatt tcaggtagtg attatacaaa agatgatgag tttatggttg
    32401 caatctctga ccatataaag agatttttaa atagagctag agctaatgta aaatcaaata
    32461 atcctttact tcatcaaata aaagagaagt ttcctatagc ttttaattta gccgtgtttt
    32521 tatcaaataa actagaaact gagtttaatt taaaacttga tgaagatgag cttggatata
    32581 tagctatcca ctttgctgct tcaaatgaaa gaatgaaaaa aaatactagt aagaaaattt
    32641 gtatagtttg tcattatggg ataggaacag gacaacttat ttctgaaaaa ctaaaacaga
    32701 atataagtga tttaagtgtt gtaggtgttt atccagttag atatctcgat atggctataa
    32761 gtcaagatgt tgatttgata gtatctaccg ttgaattaaa aggatatgaa aaacctgtct
    32821 tatatataga aaatatattt gatgatagct taattgaaaa cgtaaacaaa gccttttatg
    32881 aaaaggaaga aagaagaaag ataataagta acatgtttga tgaaaaagct tttttcagta
    32941 taaaggctag tactaaagaa gaggtcataa tttcactttc aaataaacta aaagaaagag
    33001 attttataga ggaaagttct ataaaaagta taatagatag agaaaatatt tcatcaactg
    33061 aaataggaaa tctagtagca atacctcaca caatagtgaa gggagataaa aaatctataa
    33121 taggagttgg aatacttgaa aatccaataa tttgggataa gcaagaggtt cagctagtat
    33181 ttatggtatt ttttaatact aaagaaaagc ataatttctc gatatttaaa tacctttata
    33241 attttataaa agatgaagga ggagtaagag gaattattaa aatatgtgac tttaataaat
    33301 taatggcact gataggtaat taaggaggaa attaataatg ggaacaaaca tatttaacaa
    33361 agaatatgta tttttaaatg ttgatgctaa gtcaaaggtt gaagttttaa aatttatatc
    33421 aaaaaaagct aaagacttaa acttggcaga agatgagagc ttagtatatg aaggtttaat
    33481 ggctagagaa gaacaattta ctacaaattt aggagaatct atagcaatac ctcacactaa
    33541 aaatgatgca attgaaaatc cagcagtagt agtattgaag tttaatgaag atgttgtttg
    33601 gaatgaaggt gaggataagg ttaaattagc aataagctta cttatgccag gaaaaagtaa
    33661 agagaatatt catcttaaat tattatcatc tctttcaaga aaattaataa ataaagaatt
    33721 taaagattct cttttaaaaa gtgataatgt tgaagaaata tctaacttaa taaatgaagc
    33781 tttaggttta taattaaata ctaaggttat aaaataaaaa aataattaac taaaaatagg
    33841 aggaatttga aatgaataaa aaattagtag cattatgtgc ttgcccaatg ggactagctc
    33901 acactttcat ggcagcagaa gcaatagagc aagcagcaaa ggcattaggt tatgaagcaa
    33961 aagttgaaac tcaaggtgct gatggtgtac aaaatgagtt aacaagagat gatatattag
    34021 gagcaactat gataatacat gcagtagcaa taacaccaga aggtatggaa agatttgatg
    34081 gttgtgaagt ttatgaagtt gaattacaag aagctataaa aaatgcagaa ggtgttataa
    34141 aagaaataga agaagattta ggaatataat aaatttattg tggaggaaat agaatggcaa
    34201 ttaagaaaaa agttataaac agttcaggtg cttctacaac aggaggaaat aatgtaggaa
    34261 aatctactcc atctagtcca actcaatcaa agggaaatgg aaaatggaaa gaaataagta
    34321 aacatataat gacaggtata tcatatatga taccagtttt agtaatgggt ggacttatag
    34381 gggccttatc tcaattaata ccatatgcta tattaggact tgacccatct gtaggtatag
    34441 ttgatgctat gaactcagga gaatttacag ggttcaagct tagtctttta aatatagcac
    34501 aattaatgtc aaatttcgga tttactttgt ttggatttgc gataccactg tttgcagcat
    34561 tttgtgcaaa ctctataggt ggaaaaacag ctttaattgc aggatttata ggtggatata
    34621 tagctaataa acctgtaggt gtaccacaat tcattgatgg acaatggact gaagttgttc
    34681 cagttgcatc aggattttta ggtgcaatac taatagcatt cataatagga tattttgtaa
    34741 aatggttaaa taaatctata aaagtttctc ataactggtt agcttttaaa acaacatttt
    34801 taataccatt aatagcgtca ttagcttgta tggtattgat gatatttata ataactccat
    34861 ttggtggatt aattaatgaa agtatgaaaa acttcttaac agcagcagga gcagctggag
    34921 aatatgtata tgcaacagct ttggcagcag ctacagcatt cgacttagga ggaccaataa
    34981 ataaagcagc aggattcgtt gcacttggtt taactacaga gaatgtactt ccaataacag
    35041 caagaacaat agctatagtt gttcctccaa ttggattagg attaacaaca ttattagata
    35101 aaagattagt aggaagaaga gtatatgata gacaattcta tcaagcagga aaaacttcta
    35161 tattcttatc atttatgggt atatctgaag gagcaatacc atttgcactt gagagaccag
    35221 gttttgttat acctttaaac atagttggaa gtgtaatagg agctattaca ggtataattc
    35281 taggagcaat tcaatggttc ccagagtcag ctatatgggc atggcctcta gtagataact
    35341 tatttggata tataataggt atagcagttg gtgctatatt catagcagta ggaaatatat
    35401 tctatagaaa taaattaata aaagatggta aacttgttgt agattatatc gactagtatt
    35461 taatttttac tatctataaa taactttggc tggtaatatg gttttaatca atattaccag
    35521 ccttacctat atgattaatt aaaggcggtg gagataagat atggataaga tagaaaaagt
    35581 aagagagtat tttagagaat atgatataga tggatttctt ataaatagtc ctacaaacaa
    35641 gttttatgtt ggaaatttat ttagctcttc aggttatgtt tttataacga aagaatcaca
    35701 atatataata gtagatttta gatattttga agaaattaaa agaaaatcta gtttgtttaa
    35761 tgtagtatta atggacaaaa ctagaactca ttttgatata attaatgata tttgtagaga
    35821 gcagaatata aaggaaattg gatttgaggg aaatgaagta tcttttgatt tatatagaag
    35881 tatgagtaat aagttaagtg caaccttaaa atcagttgat ttatctacat taagggaaac
    35941 aaaaaatgaa gacgaaataa aatatataaa aaaagcttgt gaaatagttg atgctacatt
    36001 ttatcatata gtagacttta taaagattgg tatgactgaa aagcaagttg aaaatgaaat
    36061 tgttagaatt ataaaagatt taggtggtca aaaagaatct ttcgatacaa tagttgcatc
    36121 tgggcttaga ggagcattac ctcatggaaa agcaagtgaa aaagttatag agtatggaga
    36181 ttttgttact tttgactttg gtgctaagta taataattat tgttcagata ttaccagaac
    36241 catttgtatg ggtactataa ataaagagtt agaagaaata tataatatag taagaaaagc
    36301 taatgaagag tgtataagag ttttaagacc gggaatgact actggagaga tagataaagt
    36361 tgcaagagac ataattggtt catatggata tgccaataat tttggtcata atctgggtca
    36421 tggtgtagga attatggttc atgaatatcc tgcattagct cctgaatcaa atgaagtatt
    36481 aaaagaagga atgattgtaa ctatagagcc tggtatatat gttccaagtc ttggaggcgt
    36541 aagaatagaa gatgatgtac tcataacaca agatggatgt atgagattga ctacatctac
    36601 taaggattta atagttgtaa gctaaaaata aattagataa atattttata acaataagaa
    36661 aagaagaggt aaatttaaat gtataatttt gatgataaac cagatagagt aagtgaaaag
    36721 tgtagaaaat gggatttaaa tattataaga gataaatttg gagatattag agaagatttt
    36781 gtaccaatgt ggattgctga tatggatttt aaaataccaa cagaaataga aaacaaattt
    36841 attgaagctg taagaagagg tgtatttgga tatacatact gttatgatga attttatgat
    36901 tcagttattg gctggcaaaa aaatatgcat gaggtaaatg tagaaaaaga atggattaca
    36961 ttaacttatg gaactgtatc aacacttcat tatgtagtac aagctttttg taagaaaggt
    37021 gatagtataa tattaaacac accagtttat gacccctttg aatcatcagc aaaaaaacaa
    37081 ggtgtaaatg taatttgtaa tacattagat gttgtaaatg atagatatta tataaatttt
    37141 gataaattag aagttcaaat taaagaaaat aagcctaaat taatgatgtt ttgtacacca
    37201 cataatccat ctggaaggat atggacaatt gaagaaatga caagagtagc aactatatgt
    37261 aaagaaaata atgttatttt ggttgcagat gaagtacatg cagagcatat tcattatggt
    37321 aaatttaatt caatacttaa gattggaaaa gagcttttag aaaatgttat tctactgaca
    37381 tcaccaaata agggctttaa tcttggtgga ttaaagactt cttattcaat agttataaat
    37441 aaggatataa gggacaaatt tagaaataaa ttaaagcaaa attctataac ttctccaaat
    37501 gtgtttggaa taataggatt gataaccgct tataatgaat gtcatgagtg gttaagtggt
    37561 gtaaatgaat atataaaatc aaattatgaa cttttagaaa cttgggtaaa taaatataat
    37621 aagataaaat tgatgaaaat ggaatcatct tacttagctt ggatggatat aagtggatta
    37681 ggtataagtg caagtgagtt tacagataag ttggctatag atacaggagt attattagaa
    37741 gatgggagtc attttgtaaa agatggtgag aagtatgtta gaataaattt aggaactcaa
    37801 aaggaaaatg taattgaagc tttaaataga atggatttat ttttaaagtc tttataaaaa
    37861 tttggttaaa ttatttattg aaaatataaa aaagtaggtt attcaattat aaaaataaat
    37921 atatttaatg gtaggcattt cttatgaaat gtctattttt atatgcttat tgtaaagttt
    37981 cctttacaat aaaatagtaa tatgatatat tatatatgta aaggaaactt tacaatgaag
    38041 gaggagatat ttttgaaaaa ttgtgtagaa gctttgagaa agaaaaaagg tcttaatcaa
    38101 gaggactttg caaaaattct taaggtttca aggcaaacga ttagttctat tgaaaatgga
    38161 aaatataatc catctttaga acttgcattt cagatatctg atttttttga aatgtcgatt
    38221 gaagaaatct ttttatggaa ggagatataa tttatggaaa aaaggaattt aagaatagga
    38281 atagtatata tagttctagg agttactttc ttgttttctt gtttaatgac taaggataag
    38341 ttaagttctt tgcttgttgg tttagcagca ggatttggat ttaatggaat ttctataatt
    38401 tatcgatatt tttactggaa taagcataag gaagaatata gagaaaagct agaagaagaa
    38461 aaaataaacc ttcaggatga aaggaatgta atgtatagag ataaagcagg acgatatgct
    38521 tatattgtgt gtatgattat aattcctata tctgcttttg ttttcgctgt actaaatgcc
    38581 ttagatatat acaactcatt agtaatcatt atatatctat ctgttttatg gattgttttg
    38641 tatgttgtag gagttattta ctatcgaaag ttaaaaaata atgaatagta tttatataaa
    38701 tttaagctat taatgtgggt atatacataa gtagaatttg ttttagatta cttaagtata
    38761 taccatattt tatataaaaa ttaaatttgc attagtcatg tgataactat ttaaattcat
    38821 gtgtattttg tatgtataat agatataatt attatttaaa cttattgttt atttaatttt
    38881 tcaatagaaa aagatttatc tgtaagttta aaattatcct ttataccctt agttaagtat
    38941 actttcttat ccttagttat gaatatagca tctacattat caattttatt aattaaatcc
    39001 ataccttttt caagaccaag tccaaatgta gaagtggata aggcatcaca attaatagat
    39061 ttatcagaaa ttattgtaac actacttaaa ttgttttcaa aaggataccc tgtaaatgga
    39121 tttaacatat gatgatatat ttttccgtct ttttcgataa atctttcata aattccagaa
    39181 gtaacaacag atttatttgt ggtttctatg tttcctatgg attcaccatt tttactagtg
    39241 gggtcttgaa tgcctatttt aaaaggttta tcatttttac catcttctaa agtaaatata
    39301 tttcctccta agtttactaa accttttttt acgtcctctg attttaaata ggctacaatt
    39361 ttatcagcag catatccttt agctatggca cctaaatcaa ttttcatatt ttctttggtt
    39421 aattttatag atttattttt ttcatccaat atgatgttct tataatcaat aagaggcaga
    39481 agtttttgta tctcagaatc acttggaact ttagctttat ctgttccaat agcccataaa
    39541 tttgataatg gaccaattgt tatgtcaaaa tatccatctg ataatttgga atattgtata
    39601 gcttctttta cgacgaaaaa tgtatcatca gaaactctga caaatttttt accagcatta
    39661 tcatttattt tagaaacatc acttcctggt atatgagtgc tcattttgtt gtcaatatat
    39721 cttaaaattg aatcacattc atttaagatt ttatcacttt tggattcttt tacattaaat
    39781 acagtaactt cgtttactgt accaaggtag tagctagttt tactatattt agtattctgg
    39841 cttgaactcc taaaaaatga aaataaaatt aatgctaaaa tcaatatcac aaaaataaat
    39901 gtgatttttt tcttattcat ggtatattcc tcctatgaga ttgtgttatt attttattat
    39961 aacataattt cataggagga caaaaaatga agaaaaaaga cattcttctt attttaggca
    40021 ttttggttgt tattacagca tgttatggga taataaatgt tataaattct aaaaatgctg
    40081 gaaatattga gatttatgta gataataaat tgtataaaac tgtttcaata aatgccaaag
    40141 aagaatttaa aatagagaat agaggggggt ataacatagt aaagattcat gataaaggag
    40201 ttgagatagt agatgcttca tgccctgata aggtttgcgt acatactgga tttataaaca
    40261 agccaagtca aagcatagtt tgtataccta atagagtgag cataaaaata aatacaaatg
    40321 aaaagaatga taatcaagaa gatataattt ctaaataaaa taatgaaaat aattgaaagg
    40381 aattggtgat aattatggtt aacttaggaa acgattggga tgaattattg aaagaagaat
    40441 ttgaaaaaga ttactactta aacttaagaa aatttcttat agaagaatat aaaacacgcc
    40501 aaattttccc aaatatgcac aatatatatg aagctttaaa acacacttca tacaaagaca
    40561 caaaagtctt aatattagga caagaccctt atcatggaga taatcaagct catggtttag
    40621 ctttttcagt tcaaccacaa gtgaaaactc caccatctct attaaatatg tataaagaat
    40681 taaaagatga tttaggttgt tttataccta ataatggata tttaatgcct tgggcagacc
    40741 aaggagtgtt acttttaaat actgctctta ctgttagagc gcatgaagct aattctcata
    40801 agaacaaagg atgggaaatt ttcactgata gagtaatatc tattttaagt gagcgtgaag
    40861 acccagttat ttttgtacta tggggaagta atgcacgtaa aaaagtagag ttgattgata
    40921 caagtaaaca ttatattttg gaagcacctc atccaagccc attgtcagca agtaaaggct
    40981 tttttggatg taaacacttc tctaagataa atgaaatttt gaaaaagcta ggaaaagaac
    41041 ctattaattg gcagatagaa aatatgtaaa agtaaaaggt aacaaaatga taacaaaaca
    41101 acaataaaca atgacattgt tgtaactaat agaaatatgc ttaaatagtt gaaaatacta
    41161 tgtatgcata tttctatttt tttgtcaagt tgacaactct tgaaaaaata gttacaattt
    41221 agttacacaa aaaacacaaa taaaaaagaa acttacaaag cagaatttta tgaagcaaaa
    41281 catatagtgt aaaaaatttt agggaggaaa ttttatatga attttaaaaa attgagtaat
    41341 gctaaagtct cggtaatggc agttgtttta tcagttggaa tattatcggg atactctgcg
    41401 cttaataaac aagtaacatt agtagtaagg ggagaagaaa gaactatatc aacatttagt
    41461 tctaatgtag gagacctttt agaatctcaa aacattagct atgatgcaaa tgatatagta
    41521 actttagatg aaaatacaaa gttatctaat ggagataaaa tagaagtaat tgatgtaaag
    41581 gaaaaaacag ttgtagaaac taaagacatt ccatttgaag ttacagttgt tgaagatggc
    41641 tctttattaa agggtgattc taaggttaaa gaagaaggaa agtctggtaa aagtgaatta
    41701 atatataaag aaacttatca caatggaaag aaagttgaaa aggaatttgt gaaaaaggtt
    41761 gttaaagctg agccagtaaa taaggttgta agcaaaggga caaaggtaga aatgcaagta
    41821 gcctcatcaa ggggagaaag ttcaagaaga atggcttcat catcatctag tagcagtagt
    41881 agtaacaatg gtaaaaatat gagagtggta gcaactgcat atactggtca cagtataact
    41941 gcaacaggaa caaaacctaa gtggggaaca atagctgtag accctaaggt tataccatat
    42001 ggaactaaag tttatatacc tcaatttgac atggtgttta ctgcagaaga ctgtggtgga
    42061 gcaataaaag gaaataaaat tgatatctac atgaatgatt caaaaacggt ttataactgg
    42121 ggaagaaaaa ctatagatat acgtatatta aaatagttaa ataatttata tttttactgg
    42181 aaattatatt ttgattatat agagaagaaa ctctttatag attcttaaaa tataatttcc
    42241 agttttttat tttggatatg taataaaaca ggtaaatttt aaccatgtat agataaaagc
    42301 tatttaaatt ataatttact atcagataaa tctataaaaa ttgttgcaaa gagtcaaaat
    42361 atatgatatt atagatttcg ttgagaagga tttcattatg ggagtggatg ggtgccggtg
    42421 tgccctctag tcttcaaaac tagtatgagg ggttaagagc ctcttaggtg ggttcgattc
    42481 ccacgcattc ccgccaatat gta
//
LOCUS       DACTZW010000031        42077 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.031, whole genome shotgun sequence.
ACCESSION   DACTZW010000031 DACTZW010000000
VERSION     DACTZW010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 42077)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42077)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42077
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.031"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(129..323)
                     /locus_tag="JAM15_08660"
     CDS             complement(129..323)
                     /locus_tag="JAM15_08660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798317.1"
                     /translation="MFQVINFLCLFCVGFLVLDVMIYFCKDAMDIFEGTTNVNKVKSI
                     NIWADRVRANSYSYENKIAK"
     gene            complement(632..2161)
                     /gene="lysS"
                     /locus_tag="JAM15_08665"
     CDS             complement(632..2161)
                     /gene="lysS"
                     /locus_tag="JAM15_08665"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HAT6798318.1"
                     /translation="MKNNQQSNEEAQIQEDLSEVLQVRRDKLKKLQESGRDPFKESRY
                     DRTHYSMDIKDNFDSLEGKTTKIAGRIMSKRIQGKAGFIDIQDQEGRIQSYVRLDAIG
                     EEEYSVFSTYDIGDIVGIEGEIFKTKKGEISVKAKSVVLLCKSLQVLPEKYHGLKDQE
                     LRYRQRYVDLIVNPEVKNAFLIRTKALKALRAYLDDRGFLEVETPILNTIAGGANARP
                     FITNHNTLHIPMYLRIANELYLKRLIVGGFDKVYEMGRMFRNEGMDLKHNPEYTAIEL
                     YQAYADYTDMMEITENVIAHMAEVATGSMIVNYQGTEINFTPPWKRMSMEDCVKEYSG
                     VDFSTINTDEEALEVAREKGIEIKPGMRRGEVINAFFEEFGEDKLIQPTFITHHPVEV
                     SPLSKRNVEDPRRTDRFEAFANKWELANAFSELNDPIDQKGRFIDQLRKRELGDDEAF
                     EMDEDFLKALEVGLPPTGGLGIGIDRVIMLLTNSPSIRDVLLFPTMKPIDNNPNKEEE
                     N"
     gene            complement(2176..2655)
                     /gene="greA"
                     /locus_tag="JAM15_08670"
     CDS             complement(2176..2655)
                     /gene="greA"
                     /locus_tag="JAM15_08670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007789163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HAT6798319.1"
                     /translation="MEENKEFLLTQEGYDKLEEELENLKVVKRKEVAERIKVAISFGD
                     LSENAEYDEAKKEQAQVEERILKLENMVRKAVIIDESKIDLNVVTIGSIVKVKDLEFD
                     EEVEYTIVGSTEADPYDGKISNESPVGKALLGRAAKEVVEVQVPDGVAKFEILEIRR"
     gene            complement(2764..3732)
                     /gene="dusB"
                     /locus_tag="JAM15_08675"
     CDS             complement(2764..3732)
                     /gene="dusB"
                     /locus_tag="JAM15_08675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HAT6798320.1"
                     /translation="MKIGNLELKNKVFLSPMAGVTDLPFRLICKEQGCGLLYTEMING
                     KALCYDDENTKKMLKIEEEEHPVAVQIFGSEPEFMGRAAEIMNDYSNEILDINMGCPA
                     PKVVKNGDGSALMKNPKLAEEVLRAVVKNSKKPVTLKIRKGWDDNSVNAVEIAKIAED
                     CGISALAIHGRTREQFYTGKADWDIIAEIKKNLSIPVIGNGDVFTIEDSINMLDKTGC
                     DAIMIGRGAQGNPWIFKRINHYMNTGEILPEPTLNEKISTAIKHLKLAVEEHGEYVAV
                     REMRKHIAWYLKGLRNSAKLRDEINKIEDYQEVVSKLEYYMEDSLT"
     gene            complement(3869..4639)
                     /locus_tag="JAM15_08680"
     CDS             complement(3869..4639)
                     /locus_tag="JAM15_08680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III pantothenate kinase"
                     /protein_id="HAT6798321.1"
                     /translation="MLLVFDVGNTNMVLGIYKGDKLVNYWRIKTDREKTSDEYGILIS
                     NLFDYDNVNISDIDDVIISSVVPNVMHSLENFCIKYCKKQPLIVGPGIKTGLNIKYDN
                     PKQVGADRIVNAVAGIEKYGAPSILVDFGTATTFCAISEKGEYLGGTIAPGIKISSEA
                     LFQSASKLPRVELAKPGMTICKSTVSAMQSGIIYGYVGLVDKIISMMKKELNCDDVKV
                     IATGGLAKLIASETKSIDYVDGFLTLEGLRIIYEKNQE"
     gene            complement(4658..5248)
                     /locus_tag="JAM15_08685"
     CDS             complement(4658..5248)
                     /locus_tag="JAM15_08685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAT6798322.1"
                     /translation="MMNTSASVRKVNVRKMTIIGVLSAISIMLSMTPLGFIPVGPTKA
                     TIMHIPVIIGAIMEGPIVGAAIGFIFGISSLLNAITNPTVTSFVFINPLVSILPRVMI
                     GVLAYYVYQLIIKATNKVYISGLITGAIGSLLNTAGVLGMIYVLYADKYLHAMGKSGS
                     AGKVIMALAAANGVPEAIVGALVVAAVATVLKKSKK"
     gene            complement(5432..6400)
                     /locus_tag="JAM15_08690"
     CDS             complement(5432..6400)
                     /locus_tag="JAM15_08690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P1 family peptidase"
                     /protein_id="HAT6798323.1"
                     /translation="MYNNILDIEGLKVGQVEDRNGLTGCTVVICEEGATCGVDVRGSA
                     PGTRETDLLDPVNMVQKVHAVVLAGGSAYGLESTCGVSRYLEEKGIGFDVGVGKVPIV
                     VGAVLFDLGVGSFKCRPDLKMGYRACEVANTDILNQGNYGAGCGATVGKIRGQEYAMK
                     GGIGSYSIKLDNGLIVSALIAVNALGDVYENGKVIAGALNDKKTETIDTYKLMKQGES
                     KGGFSVDNTTIGIIATNAKLTKAGCKKISQMGHDGYAKSIFPIHTPHDGDTIFTISTG
                     EIEADITLVGSLAVEVVEKSIINAVKKADSVENIMAYKDIVKKREI"
     gene            complement(6393..7370)
                     /locus_tag="JAM15_08695"
     CDS             complement(6393..7370)
                     /locus_tag="JAM15_08695"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HAT6798324.1"
                     /translation="MRDKIIEIILNNKSEFISGEELSKQLGVSRAAIWKHMKALKEEG
                     YNIESVNKKGYRLAENPTDLLSPQNIYYKLDTEFIGKNIEHLDTIDSTNEHAKRIAIN
                     SVDGTVILSEHQDMGKGRLGRRWDSKPHEGIWMSIILKPDMEPFKAPFITLIAGASVT
                     KALNNLGANTLIKWPNDVILNGKKICGILTELSAEIERTNYVVLGIGINVKIVDFEQE
                     IADKATSLYKEGYMLSRVDIVRNVLTEFEKLYLDYTVNNSKEKTLKICRDYSAIIDKN
                     IYVLKGDNRELVKCLDINEEGNLLVQRSDGSIKEIISGEVSIRGEKGYV"
     gene            complement(7685..9655)
                     /locus_tag="JAM15_08700"
     CDS             complement(7685..9655)
                     /locus_tag="JAM15_08700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent metallopeptidase FtsH/Yme1/Tma
                     family protein"
                     /protein_id="HAT6798325.1"
                     /translation="MNKLLKGAGFYLLVFIIIVGIVQFSGKPTEKIKDLKFSEVYREL
                     TDENISRLYFVNQTSVEGTIKDTNTKFKSYVPTEVMGNKLADEVLDQAKAGKLTFGGE
                     AKPSTPWFVEMLPTLLLIFFMVIIWFVFMNQSQGGGGKVMSFGKSKAKVHKDDEKTRV
                     TFKDVAGLDEEKEDLQEVVDFLKNPKKYIELGARIPKGMLMVGPPGTGKTYLSRAVAG
                     EAGVPFFSISGSDFVEMFVGVGASRVRDLFEQAKKSAPAIIFIDEIDAVGRKRGAGLG
                     GGHDEREQTLNQLLVEMDGFGVNQGIIIMAATNRPDILDPALLRPGRFDRQVVVGTPD
                     VKGREAIFKVHSRNKPLSDDVKMDVLARRTPGFTPADIENLMNEAAILTARKREKKIK
                     METIEEAITKVIAGVAKKSKVISEKERRLTAYHEGGHAVCAHVLEEVSPVHQVTIVPR
                     GRAGGFTMQLPVEDKFYATKNEMKENIVVLLGGRVAEELVLKDVSTGASNDLERVTAT
                     ARSMVTKYGMSSKLGPMSFDSDDEVFLGNSFSSKRNYSEEVAFEIDQETKRIVDGAYD
                     KTRSILQENMDRLEYVAQALLIYETLDAEQFVKAFNKELPLNEIENAVTEENSSKEVE
                     EQLTIKLEKDEEERNNVIDINKNLEDKSDKDK"
     gene            complement(9689..11077)
                     /gene="tilS"
                     /locus_tag="JAM15_08705"
     CDS             complement(9689..11077)
                     /gene="tilS"
                     /locus_tag="JAM15_08705"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HAT6798326.1"
                     /translation="MIFDKVLSTINKHNLIQKGDKIVLGLSGGPDSVCLLHVLNRLKK
                     DFNIEIYAAHLNHQIRGIEAQKDALYVSKLCEDMGIIFFVKSINVPKYCENEGLSLEE
                     GARKLRYEMFYEIKDKIKANKIAIGHNLNDQAETVMMRIMRGTGLKGLKGIDYIRDNC
                     IIRPILDVERNEIEEYCEAYNLNPRIDKTNLENIYTRNKIRLDLLPYMKDNFNSNVIE
                     SIVRMSNSLKSDNDYIEKEAEAKFREVSNIKEKGFVEINLDDFVCLHDAIKVRVLRNS
                     IKHILGDTNFVDQRHIEDIMSLEDNSKVNKMLTLPRNIFVYRKKDSIILTNEEIVNEE
                     IEFYYNVPSNGFIKIKELKQIIETQVMSIDRYKSMKLDNSSKGFDFNKVKGGIVIRSR
                     RQGDKIKLAMGSKKVKDLFIDLKIPREERCKIPIITDSEGIICVGDYKISENYKIDEN
                     TKEVLKINFNKL"
     gene            complement(11260..11688)
                     /locus_tag="JAM15_08710"
     CDS             complement(11260..11688)
                     /locus_tag="JAM15_08710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HAT6798327.1"
                     /translation="MEEKSLSVKISINTRQYDEKGNMDTIEMTAFGKIFYKNDGIYVI
                     YKEKEENIEITNTIKILKNQVSIKKFGAINSTMLFKCGESSTTRYVTPQGTLLIDIDT
                     RELDINIQEGEHIKLKIDYNIKVQDLFLGRNKIDIYIGTK"
     gene            complement(11705..12511)
                     /locus_tag="JAM15_08715"
     CDS             complement(11705..12511)
                     /locus_tag="JAM15_08715"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002842877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HAT6798328.1"
                     /translation="MNNKPIGVFDSGLGGLTVLKEIMKILPNEDIIYFGDTARIPYGS
                     RSKETIIKYTFQAINFLKTKGVKAIVIACNTATARSLKEAQEKYDIPIIGVIEAGART
                     AVSSTKNKIVGIIGTEGTISSKAYNLEISKIDESIEIVNKACPLFVPIVEEGWANTEV
                     AKLTAKIYLQELKEKNIDSLVLGCTHYPILKRTIGEEVGEHIKLVNPAKETAKDLKKI
                     LEVQNIINNTEIHGTYQYYVSDIHEKFSDIAREFLKKKIDKIQKVEIQKY"
     gene            complement(12713..13198)
                     /locus_tag="JAM15_08720"
     CDS             complement(12713..13198)
                     /locus_tag="JAM15_08720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase"
                     /protein_id="HAT6798329.1"
                     /translation="MATLLALTFIFMPIKEVFAYEPTENIKKVNKQEKNIAKKEVINL
                     SDNDLMLLSKLVAGEARGESYEGQVAVAAVVINRVLDPRFPDTIEEVIYQKNAFSVVL
                     DGSIKMAPTDSARKAAQEALYGTDPTNKAVYFWNPEIATCKWINRLNPYMRIGNHVFA
                     K"
     gene            complement(13249..13908)
                     /gene="spoIIR"
                     /locus_tag="JAM15_08725"
     CDS             complement(13249..13908)
                     /gene="spoIIR"
                     /locus_tag="JAM15_08725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein R"
                     /protein_id="HAT6798330.1"
                     /translation="MRKIKIRLGLLILSLISVISIMTIVINGEVKKVDNISKDYKDKL
                     IRFHVIANSNTDEDQELKLKVRDEVIKYLQPKLQNSKSIKESEAIIKKEYSGLEEISK
                     NIILKNGYNYSVKVGIQYSNFPTKQYSNIVLPAGEYKALKIIIGKGEGKNWWCVMFPP
                     LCFVDESNGVIDKSTDDKLKEVLTDKEYKLIKQDTPKKTSRVKIKFKVLEVVKDLEKK
                     F"
     gene            complement(14053..14769)
                     /locus_tag="JAM15_08730"
     CDS             complement(14053..14769)
                     /locus_tag="JAM15_08730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAT6798331.1"
                     /translation="MLLIAVKKGLKFVENLTKLNLDNYKPLRDVVFENLREAILEGKL
                     KPGQRLMEVQLAEQLGVSRTPVREAIRKLELEGLVVMLPRKGAYVANMSLKDIMDVLE
                     VRASLEGLAAYLAAERISDEDIKKLKDISEEFKKSTLESDVDALLKLDVEFHECIFKA
                     TNNKKLIQLINSLWEQVYRFRVTYMSAYDTSHNIVEEHKYLLDAIIKGDSELSKKYAT
                     EHIEKAEQFMIDKAMISKDL"
     gene            complement(14717..15607)
                     /locus_tag="JAM15_08735"
     CDS             complement(14717..15607)
                     /locus_tag="JAM15_08735"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HAT6798332.1"
                     /translation="MDFIRLKSRAKINLSIDVLGKRQDGYHFVEMIMQTIDLYDIVKI
                     KELDEDEIKVKSTSLDIPLDEDNIVYKAAKILKNKFYIKKGVEIFIEKNIPVAAGMAG
                     GSSNAAAVLVGLNHLWELRLSEDKLKEIGLNLGADVPFCISGRPALAQGIGEKLTNIK
                     GLPCDTNILICKPDLLVSTKEVYQGLDLNNIKKRPNNKYLIECLKSEDIKAVSESMVN
                     ILENVTIGKHKEISDIKQVMMKNNALGSMMSGSGPTVFGLFKNKEDALIGKKELLKKY
                     KQVYVVNSSQKGVEICGEFN"
     gene            complement(15725..17275)
                     /locus_tag="JAM15_08740"
     CDS             complement(15725..17275)
                     /locus_tag="JAM15_08740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3794 domain-containing protein"
                     /protein_id="HAT6798333.1"
                     /translation="MELIKDVIKVDNRIDFGKFQTFIEAEAVVPDKKLDVYEIVKTEG
                     YISLKKIEMADGKILCRGSFNYNVIYIADDKNTISNVDGKVDINEVIEKDNVIQDMEY
                     MLFSEVEHMDCTIMNERKIKVGALMNIRGSLFEKQRLDIVKDVAQVEGIQKHRKEICF
                     QDIVGIEKAESSIRDTITINTEEIQSIISLNPCVKVKESRVTDNKVIIGGVLEINPLA
                     CTYEGELVELDRVGIEFTQFVEVPGVSDGMTEEVLLSMSDFNHIFKQNSESNTGLLEI
                     DCMACCKVKVTDEVTREVLQDAYSPQKIIKFDHKPIQLNKTLRRSEETFMVREGIRND
                     NDDIQIKDIVSVCPTMSIENSYIEGNKSIIQGIIKVEILFVPVEGLKLVYKISEEIPF
                     EHDIEMDNLTDTASVFNTACIDKVEVDLNRDQIDLIIKIKRFTEALDKKAENFIIKGE
                     DQGVYDLSKAPSIIVYICKEGDTFWNIAKKYNTTENEIAELNDIKLDEPIKPGKCLIL
                     EKKVVLVD"
     gene            complement(17369..17635)
                     /locus_tag="JAM15_08745"
     CDS             complement(17369..17635)
                     /locus_tag="JAM15_08745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798334.1"
                     /translation="MATVQTLDKIRVSLERHIGKKILLKANKGRKQIITKEGILEKVY
                     PSVFVIKLDDESNGYPRVSYSYSDLLTSNVKLQVFRDQDKLQIS"
     gene            complement(17783..18643)
                     /gene="yabG"
                     /locus_tag="JAM15_08750"
     CDS             complement(17783..18643)
                     /gene="yabG"
                     /locus_tag="JAM15_08750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation peptidase YabG"
                     /protein_id="HAT6798335.1"
                     /translation="MKVGDIVARKSHNKDIVFKIVSFGVDENNEKIAILKGIAFRVIA
                     DAYIDDLELVKAPDIKDILIDKNVENLLYKSVRKAKERQKRMTRAVPKLQLNPNTYGM
                     PGKVLQIDGDKEYLKICLDVYAQLGIPAVGVAVSEQNQYKEVRALLEKYNPDILVITG
                     HDAMTIKRGDIEDMSNYRNSSNFVKTVKEARKWQPNLDNLVIFAGACQSNYEKIISAG
                     ANYASSPGRIMIHALDPVFIVEKIACSRIDVVVPIDEVIEQTITGVKGIGGSETRGKF
                     RWAMPKTILH"
     gene            complement(18727..19665)
                     /locus_tag="JAM15_08755"
     CDS             complement(18727..19665)
                     /locus_tag="JAM15_08755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane dipeptidase"
                     /protein_id="HAT6798336.1"
                     /translation="MKFIDLHCDTIAKLMENVETSELKSNKYSVDIDRLKKGDSLAQT
                     FALFVDTEEVKHPFDYCMSMANKFHEEMKKNSDEIALATNYEEIMKNQSEGKLTALLS
                     IEEGAVLEGKLENLKKFYNLGVRMMTISWNHVNELSFPHNKVEYREKGLTDFGREVVH
                     KMNELGMLVDVSHISDGGFYEIAKISSKPIIATHSNSRAMMNHSRNLTDDMIKVLANK
                     GGVTGINFFHLFLSDKSESKLEDMVRHIKHIVNVGGIDVVSLGSDFDGIDSKVEIEDI
                     SQMGKLYEPLKKEGFSEDDIEKIYYKNALRVIKEVL"
     gene            complement(19946..20443)
                     /locus_tag="JAM15_08760"
     CDS             complement(19946..20443)
                     /locus_tag="JAM15_08760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HAT6798337.1"
                     /translation="MSLYTEWRNLSDNHESQEAEVKFWEEYLKVEAGIYNEILNNKMD
                     VVEGKVSELAEKFGTTNEFFMGFIDGISESLKEDIVLEEVEADKEVSIKIDWEKLYNN
                     MVTVEAHWLYNLQGWEDILPADQRKEIIKAYKKSKTIVKEAKIGRNDSCPCGSGKKYK
                     KCCGK"
     gene            complement(20558..21268)
                     /locus_tag="JAM15_08765"
     CDS             complement(20558..21268)
                     /locus_tag="JAM15_08765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798338.1"
                     /translation="MENYEYSGFYIEKPVGNNVFSYDKRENKSIYVPKLINGTLNDVR
                     LGNEVVFNEVDENKEIKAKGLDNMVEYVLGNKKIYVFDNHNHAFYFWAKSLLKGEFTK
                     GCKLVHVDQHKDTREPENYDVDVNNLKDVFRYTNEVLNVGSFIKPALKYNIFSELIII
                     DSLYGFDLEVESEFVLDIDLDIFSSDMDYIPFELKFYKIKNLIKKAKVITIATSPYFI
                     NQEYAIKVLKELFNYDII"
     gene            complement(21444..21974)
                     /locus_tag="JAM15_08770"
     CDS             complement(21444..21974)
                     /locus_tag="JAM15_08770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798339.1"
                     /translation="MDIRALPIRITKEEAIEIAKSGKNSLFSKLILKNKYAHEVRLHY
                     IEFKIITLKIHKTKSIFKNRRYSNDINELKILVNGSTGSGSIVQDFPTYEIVKNVDCN
                     IVQYSNKDERRVKAKANKMAMRLIHRFMGGIPEIEIVKIESIFRPYWVVFFGKVELNR
                     RVSYLPIEADGFVIGM"
     gene            complement(21991..22221)
                     /locus_tag="JAM15_08775"
     CDS             complement(21991..22221)
                     /locus_tag="JAM15_08775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798340.1"
                     /translation="MSKLVSKVKKDLEIKWLGIDGFLVLLYFLITGFIFYGILTRNDI
                     IVGKIIPYGVMAVVIVIFFDYIYRVLKMTRKK"
     gene            complement(22236..23630)
                     /locus_tag="JAM15_08780"
     CDS             complement(22236..23630)
                     /locus_tag="JAM15_08780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HAT6798341.1"
                     /translation="MLTFWENGIIVIFAFILLGIGYYFSRNVKDMESYYLGNRSLPWS
                     LIVGTLVASWYGGVGTVGSVEYAAIYGISAWAVWSIAAHIGRMPLALWVGPRIHIRTN
                     ITVPDLLESFYGKHVAIIGAILMFIYCAQLGEITAMGTIGNVAWKIDKELIGLIMVGV
                     VVVLTVLGGLMGVAITDMVLFFCMVFGLTMVMPGQFEQIGGFQGLTEALKDAPQLMHP
                     TKGMSAMKALMLIVYSFGAYSDPTFYQRFSAADSPKVGRRALLTCFSLWICFDMVLTI
                     TGLIVRATYPEMAPAAGYITLVLDTLPQGIRVIFIIGILGSIISTLDSYYLAAGATLA
                     NDIYGRITKKELSQKQLVKFTRIGVCLAAVMGLSVAFRFENVYDACIFVGSIWMGSAF
                     VPIVGGLLGNGRRTSMGGILGMIVGGVTFGYFKIFPVQSFELEPLVIAIPFSFIAWMI
                     GNRIGEDLNIQNNL"
     gene            complement(23756..25009)
                     /locus_tag="JAM15_08785"
     CDS             complement(23756..25009)
                     /locus_tag="JAM15_08785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAT6798342.1"
                     /translation="MESKNNVKRFLIIFILAFGTTAMYSLPYMKSSFYDPMQQALALS
                     HTQIGNLLSLYGLVGMISYFIGGWFADRFSVRKLITFSLIASGVLGFYFSTFPSYSMI
                     LLIFVLWGFTTILTFFSASVKVVRMQGSESEQGRIFGFYEGLSGVSGTLISFIGLYFF
                     GKFAEITVGFKYVVWLYSAASIICGILLFFLVEEKKDSGASDEGLSIKSLLKVVTMPK
                     AWLIGLIIFSTYLVFSSLTYLSPYLSEVYVMPMTLVSALSIIRTYVIKMGASPVAGVI
                     TDKVGSSIRVMFVGFILMTVSTAAYLVIPKSTGFIWIAVINMIILSVILFGFRGIYFA
                     SVSESNISLETTGAVVGFASFIGFSPDAFYYTIAGNWLDKYGQTGYTYIFILSVVCAV
                     IGIFATYALNKINKRENKGLNNKIA"
     gene            complement(25060..26214)
                     /locus_tag="JAM15_08790"
     CDS             complement(25060..26214)
                     /locus_tag="JAM15_08790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HAT6798343.1"
                     /translation="MSNNINQDLETKIIHWGHSADPTTGALATPICQTATFAAKTVEH
                     FEELCMTWGYVYTRECNPTLTELEAKLAMLENAESAISSTSGMGAITSTILALVKSGD
                     HIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPS
                     LDLVDIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLG
                     GAVAGSKELIDLVRWPSLCCFTGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEF
                     LEEEENVELVKYPALKSHPQYELCKTQMNGLGGGVVSFKLKDGINGLTRDQASRKLMN
                     SLELATIATSLGEEHTLVQMNGENLIRIAVGLESSNDIINDFKQAIKKLK"
     gene            complement(26773..27342)
                     /locus_tag="JAM15_08795"
     CDS             complement(26773..27342)
                     /locus_tag="JAM15_08795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAT6798344.1"
                     /translation="MIIIYGYCRVSTKNQTDNNSLYQQQQEILNKYNDAKIIKETYTG
                     TTTNRPKFEKIISSLKKGDLLVATKLDRLARSTSEGIQLIEGLFAKEVSVHILNIGLL
                     ENTSMGKFFLTTLLAVAELERNMIIERTQLGKEFAKKKKDFKDGRPKKYSNQQIQYAL
                     GLLNSKPYREVVKMTGISKSTLIRAKKSI"
     gene            27545..27772
                     /locus_tag="JAM15_08800"
     CDS             27545..27772
                     /locus_tag="JAM15_08800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAT6798345.1"
                     /translation="MNSLLKEAIDELKNIHCGEVFLLKELFKGYEWNRLEMNIRLKLG
                     KLFLYEVVTNPNLNVEVINKNSAYQQMYKKK"
     gene            complement(27991..28734)
                     /locus_tag="JAM15_08805"
     CDS             complement(27991..28734)
                     /locus_tag="JAM15_08805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HAT6798346.1"
                     /translation="MENYQSTNTCTYNILYVQFNEDFERSKYFSYDVKYPVIYNIRNQ
                     STYVNPVILNNINNAVRMTVNNFKNGLQEEEREHNNAASQNSLPKQSYWVSTSYAVTF
                     NKNYVLSMILNLMGFANNYGPKYNTLNNYNIDLTTGKELLLNDIFRDGVDYINIITDY
                     IKSQINENREMYYSNVELVIPEDQAFYITDNGIIIYFGVDEIAPESFGIPKFELKFSD
                     FGNFINLRFYCISPDIYVQSRGRAKHFMG"
     gene            28902..29774
                     /locus_tag="JAM15_08810"
     CDS             28902..29774
                     /locus_tag="JAM15_08810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HAT6798347.1"
                     /translation="MLLLADKWKDYELIDMGNGEKLERWGSYVLRRPDPQVVWPMESE
                     WALWKNPHGHYHRSNKGGGQWEHKKRYPEQWTINYKNLKFHIKPTGFKHTGLFPEQAA
                     NWDWMIEKIKKANRPIKVLNLFAYTGGATVACASAGAEVCHVDAAKGMVNWAKENIEL
                     SGLKNQTVRFIVDDVVKFVEREIRRGKKYDAIIMDPPSYGRGPKGEVWQIEEKLYSFV
                     DLCMGVLSDNPLFFLINSYTTGFSPIVLENVLSTTIGKKTNTGDIYGGELGIPASRDG
                     KILPCGIFGRWEKK"
     gene            29774..30439
                     /locus_tag="JAM15_08815"
     CDS             29774..30439
                     /locus_tag="JAM15_08815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAT6798348.1"
                     /translation="MIKVIYEDNHLLVVEKPVNILSQGDNTNDKDMVNLLKDYIKKKY
                     NKPGNVYIGLIHRLDRPVGGVMVFAKTSKAASRLSEQVRSKTFKKTYLAVVHGKIKSN
                     SDILKDFLYKNKKTNMVTVVKKSHKDAKEAELNYNVLDFKENLSLVQVNLKTGRSHQI
                     RVQFASRKHPLYGDQRYGKEINKIGQQISLWSNKIEICHPTTKEKMEFTCHPPDKYPW
                     NIF"
     gene            30460..31317
                     /locus_tag="JAM15_08820"
     CDS             30460..31317
                     /locus_tag="JAM15_08820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAT6798349.1"
                     /translation="MSKKFSIGEMSKLHKISIQTLRYYDQIDLFKPVHVDQESNYRYY
                     SIDQFSQLDIIKYLKYLGMPLKEIKSKLDENNEEILKLLTNKINIVDEKIKELELIKK
                     VLSTKKETMEKGMKVDEVGKIVRKHIPRRSILSIEYEEGLSSEETMELSRRQIANILE
                     DNISVFYGGVSGLVSIDKFLKEDKVIYDNSFVTVERDLFDIKSQKHITEISSGDFICM
                     TYKGPYKENYTAFKKLVDYVEYKRIPIENYIYEIPIIDPLSTNNEEELLTEIQIQVKK
                     REIDLRCLV"
     gene            complement(31473..34019)
                     /locus_tag="JAM15_08825"
     CDS             complement(31473..34019)
                     /locus_tag="JAM15_08825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAT6798350.1"
                     /translation="MNIFNKVALQGLKKNRTRTLVTIIGVVLSAAMITAVTTFGVSLM
                     NYMTNGAIIKYGDWHVQFLDVDSSFVQEQRVNDEVANTATFENIGYATLEGNRNPDKP
                     YLFIAGFSKEAFDTLPITLISGRLPENSREILVSSKVATDGGVKFAVGDTISLDVGKR
                     MSENEKLGQSDPYTAGSEVFVPQDKKTYTVVGICRKPVFEESSAPGYTLITKEDKQVK
                     TDSLSLFVTLKNPHQIRSYTSSTKDHASIFNDNVLRFIGVSDNNLFNMFLYSVGGIVL
                     AIIMLGSIFLIYNSFNMSLNERTHQFGILSSVGATAKQLRNSVLFEGICIGAIGIPIG
                     VAIGIVSIGLVISVIAKNFANILYVNVPLTLTLSIPAIIVAAVVGMVTILISAYIPAR
                     KAANTPVMECIRQTNEVKIESKSVKTSKLTQRVYGLEGVLAMKNFKRNKKRYRSIVLS
                     LVLSIVLFISTSALVADLKQMSNQRSEVTDQDIIFSTQGMKDNEMLKLYDKLKTANGV
                     YEGLYQKLMTYSCVAKVSELTDDYLNYEGSHSMSEMLELPVDMQFLDDRTYLNIIKSL
                     GLPAEEYTGQNAKLIAVSMVTKDNNIIDIFNSSSMNVSLTPETNSKLEIPERQNVNIS
                     FVKVVPPDSPPGIRSSDVKKASFRVLAPYSAKDKFEIPGVSTGIESLSFQSKNPTQSV
                     AEMEQIIESEGVTNEYNLYNMYGMMDENRNYIFIANVFAYTFIIMISLISIANVFNTI
                     STNIKLRRRELAMLRSVGMSEHDFQKMMNFECAFYGMRALFFGLPIAVISSWLIHKVM
                     VTDDIDFVIPWFSIGISIFSVLFIVFITMLYTINKIKKENIIDALRDDMA"
     gene            complement(34019..34705)
                     /locus_tag="JAM15_08830"
     CDS             complement(34019..34705)
                     /locus_tag="JAM15_08830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6798351.1"
                     /translation="MAFLKIEDLCKVYGKNENKVTALDHVSLTIEKGEFTAIIGSSGS
                     GKSTLLHSIAGVDVPTSGKIYLEGQDVYGQSNEKLAIFRRRQVGLIYQFHNLIPTLNV
                     VENITLPILMDKRKVNQERLNDLLELLGLKERKTHLPNQLSGGQQQRVAIGRALMNAP
                     AVMLADEPTGSLDSKNGQEIIQLLKESHSKYHQTLIIVTHDENIALQADRIICISDGK
                     VVRDERKVNR"
     gene            complement(34788..35777)
                     /locus_tag="JAM15_08835"
     CDS             complement(34788..35777)
                     /locus_tag="JAM15_08835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003483104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAT6798352.1"
                     /translation="MFRNREFRKFAILFLLITILTVALGFAISIMTGILSIVSATTFG
                     IAFFVFTKNRYKSIAQISEQINLVLHNANHLYIAESDEGELSILQSEITKMTLRIREQ
                     NYALKKEKEHLADSLADIAHQLRTPLTSVTLILSLLENTSDEDERKELIRETEELLIR
                     MDWLITSLLKLSRLDAGIVVFQKEQIDVSNLISSALHQLLIPMELHNITLHIDIPKGV
                     RILGDLNWLSEAIQNIFKNCMESVGDNGKINIVCEDNFLFTQLTIHDNGAGFKKEDLP
                     CLFNRFYRGKNSSTAGYGIGLALCKTIIMRQGGTITAQNHPQGGAIFVIRFPK"
     gene            complement(35764..36450)
                     /locus_tag="JAM15_08840"
     CDS             complement(35764..36450)
                     /locus_tag="JAM15_08840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012102957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6798353.1"
                     /translation="MKRIFLVEDDKAIAKNLILLLNSEGFIVTHVSTRSEALVEIAKN
                     KFDLALIDISLPDGNGFTICTEIKEKQDIPVIFLTASGDESSVVTGLNMGADDYITKP
                     FRPRELIARIRTALRKSGRFGSTFEICGLYVDTATGVVKKNGNEVFLSALEYRLLLVF
                     ISNPKSIITRVRLLDELWDAAGEFVNDNTLTVYIKRLREKIEDDPSSPQIILTVRGTG
                     YRLGGSYVSK"
     gene            complement(36950..40156)
                     /gene="carB"
                     /locus_tag="JAM15_08845"
     CDS             complement(36950..40156)
                     /gene="carB"
                     /locus_tag="JAM15_08845"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002844223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HAT6798354.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQALKEEGIEV
                     VLVNSNPATIMTDKEIADKIYIEPLTIEFIEKIIEKERPDSLLAGMGGQTGLNLAVEL
                     HDAGILDKYNVKVIGTSIESIKKGEDRDLFREVMKEINQPVIVSDIVTNLEAGLEFAN
                     KIGYPVVVRPAYTLGGTGGGIADTEEELREILSHGLQLSPVGQVLLEKSIKGWKEIEY
                     EVMRDGNGNCITVCNMENVDPVGVHTGDSIVVAPSQTLSDEEYQLLRKASIDIINAIE
                     VQGGCNVQIALNPHSLEYAIIEINPRVSRSSALASKATGYPIAKVAAKIALGYTLDEI
                     ENAVTKKTYACFEPTLDYVVVKIPKWPFDKFRHANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHAPSEGRTLEELKARVVVPDDERLFDLAEMIRRGYKVEMISE
                     ITGVDKWFINKFKWIVEQEEKLKVLKIEDLDKEYLHELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIQPVYKMVDTCGGEFEALSPYYYSTYEQYDEVVVSDKRKVVVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMGIETIIVNNNPETVSTDFDTSDKLYFEPLTEEEVLNI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFRDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWSLNEGIEVAKELGYPVLVRPSYVLGGQGMEITYNEEKLIQYLDDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGDSTTMYPSQNISDE
                     IKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNPRASRTVPYISKVSGVPIV
                     DLATKCMLGAKLKDLGYGTGVYKEPKLVSVKVPVFSMSKLSKVEVSLGPEMKSTGEVL
                     GVGENLEEALYKGFLAAGRHMSDERGVVLATVNNHDKDEFIEIAKDMKELGYTFVATE
                     GTANSLRENGIEADIVNRIEEPRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKMRRT
                     AIEFSTEIMTSLDTLKALVEVKKKHLNKDKLKVYNIAE"
     gene            complement(40349..41398)
                     /gene="carA"
                     /locus_tag="JAM15_08850"
     CDS             complement(40349..41398)
                     /gene="carA"
                     /locus_tag="JAM15_08850"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002845470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HAT6798355.1"
                     /translation="MKARLILEDGTVFIGKAFGYLEESVGEVVFNTSMIGYGEVLTDP
                     SYYGQIVTMTYPLVGNYGINLSSAESEKVQVKGFIVREKSDSPSNFRCEIDIDQYLKQ
                     NKVIGLEGIDTRALTKILRNNGTMKGIITLEDSKLEDVKHKLDKFSNTEAVRTVTRKE
                     VEHIKGNGTKVAVMDFGVKRNILRSFIARGCDITIFPATTSPEDVLSINPDLIFLSNG
                     PGDPEDLEDVIENIKALIGKKPIVGICLGHQLLALALGGKTAKLKFGHRGGNHPVKDL
                     EEGKVFITSQNHGYYVSEVPEQMKVTHINLNDNTVEGMRHEKLDVYSVQYHPEACPGP
                     KDNDYIFDKFLELVK"
     gene            complement(41655..>42077)
                     /locus_tag="JAM15_08855"
     CDS             complement(41655..>42077)
                     /locus_tag="JAM15_08855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002844223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HAT6798356.1"
                     /translation="LAAGRHMSDERGVVLATVNNHDKDEFIEIAKDMKELGYTFVATE
                     GTANSLRENGIEADIVNRVEESRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKIRRT
                     AIEFSTEIMTSLDTLKALVEVKKKHLNKDELKVYNIAE"
BASE COUNT        13297 a         7857 c         4663 g        16260 t
ORIGIN      
        1 ttcgtcaata ctttttttgt tttttatttt aaaaaaggtt ataacttttg gtttttttaa
       61 taaatataat taaaactaat agatataacc cttgatatta caaacaatac atgcatatat
      121 aattttacct attttgcaat tttattttca taagaatatg aattagctct cactctatct
      181 gcccaaatat ttatactctt aactttatta acattagttg taccctcaaa aatatccatt
      241 gcatccttac aaaaatatat cataacatca agaaccaaaa atccaacaca aaataaacat
      301 aaaaaattaa ttacttgaaa catcagacat tcccccaata attttttata tatagtattc
      361 tcataaatta ttctttttac cttctcataa attattctaa atattttcat aataaattac
      421 tttcaatcat attttctaaa tataaagtct caatcaacaa aaactaatat caatttctaa
      481 cgtttgttgg taatttataa attaaatatc taaaagaatc tttgaagcat ataaaaagca
      541 ttctacactg acattttaaa caaaatttag ctatttattg ctaatttaat agctaaactt
      601 tatttaaaac ttagtagaat gctaatattt cttagttttc ttcttcttta tttggattgt
      661 tatcaatagg tttcatagtc gggaataata atacatctct tatagatgga gagttagtta
      721 ataacataat tactctatct atacctattc ctagtcctcc tgtaggaggt agacctacct
      781 ctaatgcttt taagaaatct tcatccattt caaaagcttc atcatcacct aattctcttt
      841 ttctcaattg gtctataaat cttccttttt ggtcaatagg gtcattaagt tcagaaaatg
      901 cattagctaa ctcccactta ttagcaaatg cctcaaatct atcagttctt cttgggtctt
      961 caacatttct cttagataat ggagatactt caactggatg atgagttata aatgttggtt
     1021 ggattaattt atcttctcca aattcttcaa agaaagcatt tattacttct cctcttctca
     1081 ttccaggttt tatctctata cctttttctc tagcaacttc tagtgcctct tcatctgtat
     1141 ttatagtaga aaaatctaca ccagaatatt ctttaacaca atcttccata ctcattcttt
     1201 tccaaggtgg tgtaaagttt atttctgttc cttgatagtt aactatcata cttcctgtag
     1261 caacttcagc catatgtgca ataacatttt ctgttatttc catcatatca gtatagtctg
     1321 catatgcttg atataattct attgcagtat attcaggatt atgttttaaa tccatacctt
     1381 catttctaaa cattcttccc atttcataaa ctttatcaaa tccaccaaca ataagtcttt
     1441 ttaaatacaa ttcatttgct attcttaaat acattggtat atgtaaagta ttatgattag
     1501 ttataaatgg tctagcattt gccccacctg ctatagtatt taatattgga gtctcaactt
     1561 ctaaaaatcc tctatcatct aagtatgctc ttaatgcttt taatgctttt gttctaatta
     1621 aaaaagcatt ttttacttct ggatttacta ttaagtcaac atatctttgt ctatatctta
     1681 gttcttggtc ttttaatcca tgatattttt ctggtaaaac ttgtaaagat ttacatagta
     1741 atactacaga tttagccttt acagatattt cacctttttt agttttaaag atttctcctt
     1801 caattccaac tatatctcca atatcatatg ttgaaaatac actatattct tcctctccta
     1861 tagcatctag tcttacataa gattggattc ttccctcttg gtcttgaata tctataaagc
     1921 cagctttccc ttgtattctc ttgctcatta tacgtcctgc tatttttgta gttttacctt
     1981 caagagaatc aaagttatct tttatatcca tagaataatg agttctatca tatctacttt
     2041 ctttaaaagg atctctacct gactcttgta atttttttag tttatctctt cttacttgaa
     2101 gtacttcact aaggtcttct tgaatttgcg cttcttcatt gctttgttga ttatttttca
     2161 tttttttcct ccaaattatc ttcttatttc taatatttca aacttagcaa ctccatcagg
     2221 aacttgcact tccacaactt ctttcgcagc tctacctaaa agtgctttcc ctacaggaga
     2281 ttcgtttgat attttaccat catatgggtc tgcttctgtc gaaccaacta tagtatattc
     2341 aacctcttca tcaaattcta aatccttaac tttaactatt gatcctattg taacaacatt
     2401 aaggtctatt ttgctttcat ctatgataac agcttttcta accatatttt ctaattttaa
     2461 aattctttct tcaacttgtg cttgttcctt tttagcttca tcatactcag cattttcaga
     2521 taaatcacca aaagatatag caacttttat tctctctgca acttcttttc tctttacaac
     2581 ctttaagttt tctaattctt cttctaattt atcatatccc tcttgtgtca ataaaaactc
     2641 tttattttct tccattataa atacaactcc ttcacaaatt tcttaggaat tttcctaatt
     2701 atattttaaa aattttataa tcttttttta atttatgcgc tatattataa gtcactatta
     2761 tttttatgtc aaggagtctt ccatatagta ctccaatttc gacacaactt cttgatagtc
     2821 ttctattttg ttaatttcat cccttaattt tgcagagttt ctaagtcctt ttaaatacca
     2881 agcgatgtgt tttctcattt cccttacagc tacatactct ccatgttctt ctactgcaag
     2941 ttttaaatgc ttaatggcag tacttatttt ttcgttaaga gttggctctg gcaaaatctc
     3001 gcctgtattc atataatggt ttattctttt aaatatccaa gggttacctt gagcacccct
     3061 acctatcatt atagcatcac aaccagtttt gtctaacata tttattgaat cttctattgt
     3121 aaatacatca ccatttccta taacaggtat actcaaattt ttcttaatct ctgcaattat
     3181 atcccagtct gctttgcctg tataaaactg ttctctagtt cttccatgta ttgctaaagc
     3241 gcttattcca caatcctctg ctatctttgc tatttcaaca gcatttacac tattatcatc
     3301 ccagcctttt cgaatcttta aagtcactgg cttttttgag ttcttcacta ctgccctcaa
     3361 tacctcttct gcaagcttag gatttttcat aagtgctgaa ccatctccat ttttaactac
     3421 ttttggagct ggacacccca tatttatatc gagaatctca tttgaataat cattcattat
     3481 ctctgctgct cttcccataa actctggttc tgaaccgaat atctgaactg ctacaggatg
     3541 ttcttcctct tctatcttaa gcattttttt agtattttca tcatcatagc aaagtgcctt
     3601 accatttatc atttctgtat ataaaagccc acatccctgt tctttacaaa ttaatctaaa
     3661 tggaaggtct gttacacctg ccataggtga tagaaaaact ttatttttca attctaaatt
     3721 tcctattttc attgtttttc tcctattttt acctttattt tgtgatttaa ctttaaattc
     3781 ttatttcctc attataatat accacatata gctagaaatc tatcataaaa agggaattgg
     3841 atatataacc caattccctg tatattaatt attcttggtt tttttcatat attattctca
     3901 atccttctag tgttaaaaaa ccatctacat aatctatact tttcgtctct gaagcaatca
     3961 gtttagctaa tccacctgta gctataacct taacatcatc acaattcaat tctttcttca
     4021 tcatacttat tattttgtca actaaaccaa catatccata aattattcca gattgcatgg
     4081 ctgatacagt actcttacaa atagtcatac ctggcttagc taattctact ctaggtaatt
     4141 tagacgcact ttgaaataac gcctcactag atatttttat tcctggtgct attgttccac
     4201 ccaaatattc acctttttca gagatagcac aaaatgtagt tgctgttcca aaatcaacaa
     4261 gtatacttgg tgctccatac ttttctatcc ctgctacagc attaactatt ctatctgccc
     4321 caacttgttt tggattatca tattttatat ttagacctgt ttttatgcct ggacctacta
     4381 ttaatggctg ttttttacag tactttatac aaaagttttc aagagaatgc ataacattcg
     4441 gaactacaga tgatattata acatcatcaa tatcacttat attcacatta tcataatcaa
     4501 ataggttact tatcaggatt ccatattcat cagacgtttt ttctctatct gttttaattc
     4561 tccagtaatt aactaatttg tcacctttat atatacctaa aaccatatta gtatttccaa
     4621 catcaaatac tagaagcata tgtcattaac cttctttcta ttttttgctt ttcttaagta
     4681 cagtggcaac agcagctact actaaagccc ctactattgc ttctggcacc ccatttgctg
     4741 cggcaagagc cattattact tttcctgctg aaccactttt acccattgca tgaagatact
     4801 tgtcagcata taagacatat atcattccta aaactccagc tgtatttaac agagaaccta
     4861 ttgcccctgt aattaaacct gatatgtata ccttatttgt agccttaatt attaactgat
     4921 atacataata agctaataca cctatcataa ctcttggtaa tattgaaact aatggattta
     4981 taaaaacaaa agatgttact gttgggtttg ttatagcatt taagagactt gatatcccaa
     5041 atataaatcc tattgctgcc ccaactattg gtccttccat aatagctcca ataataactg
     5101 gtatgtgcat tatagttgct tttgtaggtc caactggaat aaatcccaat ggagtcatag
     5161 atagcataat agaaatagct gatagtactc ctattatagt catctttctt acatttactt
     5221 ttcttactga tgcacttgtg ttcatcataa aaaatacacc tccgttccag ctcattaaga
     5281 tgccggacta cttaattttt taattttttt cgtttttttc ttataactat gagtcaagct
     5341 accattgtag gatgcccgct ctaacaagaa taattttatc aagatgagtt gccattgtca
     5401 acaatttgac aagaaaaata tgctaatttc atcatatttc tcgttttttt actatatctt
     5461 tatatgccat tatattttct acactatccg ctttttttac tgcatttatt atactttttt
     5521 ccacaacctc tacagccaat gaacctacta atgttatatc tgcttctatt tctcctgttg
     5581 atattgtgaa tattgtatct ccatcatgag gtgtatggat aggaaaaata gacttagcat
     5641 atccatcatg tcccatttga gatatctttt tacatccagc tttggttaac ttagcatttg
     5701 ttgcaattat cccaattgta gtattatcta cactaaatcc acctttactt tcaccttgtt
     5761 tcattaattt atatgtatca attgtttctg tctttttatc atttaaagca ccagctataa
     5821 ccttaccatt ttcataaaca tctccaagag catttacagc aattaatgca gatacaatta
     5881 gaccattatc taattttata gaatagctac ctattccgcc tttcatagca tattcctgac
     5941 ctcttatttt tccaacagtg gctccacaac ctgctccata atttccttga tttaaaatat
     6001 cagtatttgc aacttcacaa gctctataac ccatctttaa atctggtcta catttaaagc
     6061 tccctactcc taaatcaaat aaaactgctc ctacaactat aggcacttta cctacaccta
     6121 catcaaagcc aattcctttt tcttctaagt atctacttac accacaagtg gattcaagac
     6181 catatgcaga acctccagcc aaaactactg catgaacttt ttgaaccata tttacagggt
     6241 ctaataaatc ggtttctcta gtccctggag cagagcccct tacatcaaca ccgcaagtag
     6301 ctccttcttc acatattact actgtgcacc cagtaagacc atttctatcc tcaacctgcc
     6361 caacctttaa gccttctata tccaaaatat tattatacat atcctttttc tcctcttata
     6421 gaaacttcac ctgaaataat ttcttttata cttccatcac ttctttgaac taataaattt
     6481 ccctcttcat ttatgtctaa acatttcact agttctctat tatctccttt taatacatat
     6541 atatttttat ctataattgc agaataatct ctacatattt ttaaggtttt ttctttggaa
     6601 ttatttacag tataatctaa atataatttt tcaaattcag tcaatacatt cctaacaata
     6661 tctactctgg ataacatata tccttcttta tacaatgatg tggctttgtc agctatttct
     6721 tgttcaaaat ccactatttt aacatttatt ccaattccaa gaacaacata gtttgttctt
     6781 tcaatttcag cagataactc tgttaatata ccacatattt tttttccatt taaaataaca
     6841 tcatttggcc attttattaa tgtatttgct cctagattgt ttaaagcttt cgttacactt
     6901 gctcctgcta ttaaagttat aaatggagct ttgaatggtt ccatatctgg ttttaatata
     6961 atactcatcc agattccttc atgaggtttt gaatcccatc ttcttcccaa tcgtcctttc
     7021 cccatatctt gatgttcact taaaatcaca gtcccatcta cactatttat agctatcctt
     7081 ttagcatgtt catttgttga atctatagtg tcaagatgtt caatattttt tccaataaac
     7141 tctgtatcta atttatagta aatattctgt gggcttaata aatcagttgg attttccgct
     7201 aatctatacc cttttttatt tacagattct atattatatc cctcttcttt taaggctttc
     7261 atatgtttcc atatagctgc acgtgacacc cctaattgtt ttgataattc ttctcctgaa
     7321 ataaattcag atttattatt taatataatc tctattattt tatctcgcat atttcacctc
     7381 taatatgaca taatttcatg acttattttc ttctaataaa taattataca ttattaatat
     7441 acttttaata ctattaattt taaatttcct ttttaattat tataatagtt gttttatatt
     7501 ttatattgat gatttatatg attttacatt ttatttaaat aattttaaaa taataaaaaa
     7561 actgaaagta tcaattaaat taatacatgc aaatataatt tgcttattaa tttaatatta
     7621 tactttcagt tttagtattt aatccacatc agataataat cttaaaatga ccaaggtctt
     7681 aaaactattt atctttatca gatttatctt ctaaattttt atttatatca ataacattgt
     7741 ttctttcttc ttcatctttt tctaatttta tagttaattg ttcttcaact tctttagaag
     7801 aattttcttc tgtaactgca ttttcaattt cattcagagg taactcttta ttaaatgctt
     7861 ttacaaattg ttctgcatct aaagtttcat atataagtaa agcttgtgct acatactcta
     7921 atctatccat attttcttgt aatatacttc ttgtcttatc atatgcacca tcaactatac
     7981 gctttgtttc ttggtctatc tcaaaagcaa cttcttcaga ataatttctc ttacttgaaa
     8041 aactattacc taggaatact tcatcatcac tgtcaaatga cattggacca agtttagaac
     8101 tcattccata ctttgttacc atacttcttg cagtagctgt aactctttct aagtcatttg
     8161 aagcacctgt agatacatcc ttaagtacta gctcttctgc tactctacca ccaagtaaaa
     8221 ctacaatatt ttctttcatt tcattttttg tagcatagaa cttatcttca acaggaagtt
     8281 gcattgtaaa ccctccagct cttcctcttg gaactattgt aacttgatga acaggactta
     8341 cttcttcaag tacatgggca caaactgcat gccctccttc atggtatgct gtaagtcttc
     8401 tttctttctc acttattact ttcgattttt tagccacacc tgctataacc tttgttatag
     8461 cttcttctat agtttccatc ttaattttct tttctctttt tctagctgtt aatattgcag
     8521 cctcattcat taagttctct atatcagcag gagtaaatcc tggtgttctt ctagccaaga
     8581 catccatttt tacatcatca cttaatggtt tatttcttga gtgaacttta aatatagcct
     8641 ctctaccttt tacatctggt gtaccaacaa caacttgtct gtcaaatctt cctggtctaa
     8701 gtaaagctgg gtcaagtata tctggtctat ttgtagctgc catgattatt ataccttgat
     8761 ttaccccaaa tccatccatt tcaactagaa gttgattaag agtttgctct ctttcatcat
     8821 gacctccacc aagacctgca cctctttttc taccaactgc atcaatttca tctatgaata
     8881 tgatagctgg agcacttttc ttagcctgtt caaataaatc tcttactctt gaagcaccaa
     8941 ccccaacaaa catctcaacg aaatcagaac cacttatact gaaaaaggga actcctgctt
     9001 ctcctgcaac tgctcttgat agatatgttt taccagttcc aggaggtcct accataagca
     9061 ttccttttgg tattcttgca cccaattcaa tatatttctt aggattcttt aagaaatcta
     9121 ctacctcctg caaatcttct ttttcctcat ctagtccagc tacatcttta aatgtaactc
     9181 tagttttttc atcatcttta tgaaccttag cttttgattt gccaaaactc ataacctttc
     9241 cgcctccacc ttgagactga ttcataaaca cgaaccaaat aatcaccatg aagaatatta
     9301 acagtaatgt aggcaacatt tcgacaaacc aaggtgtaga tggcttagct tcaccaccaa
     9361 aagttagttt cccagcctta gcttggtcta acacctcatc tgcaagttta tttcccatca
     9421 cttctgttgg aacatatgac ttaaactttg tatttgtatc ttttatagta ccttctacag
     9481 aagtttgatt tacaaagtat aatcttgata tattctcatc tgttaattct ctatatactt
     9541 cagagaattt taaatctttt attttttctg taggcttacc tgagaattga actataccta
     9601 ctataattat aaaaacaagt agataaaaac ctgccccttt tagcaactta ttcaatatag
     9661 aagccctcct ttcatacatt gctttgccct ataatttgtt aaaattaatt tttaatactt
     9721 cttttgtgtt ttcatcaatt ttataatttt cactgatttt ataatctcca acacatatta
     9781 ttccttcact atctgtgatt ataggaattt tacatctttc ttctcttggg atttttaaat
     9841 ctatgaataa atctttcact tttttacttc ccatagcaag ctttatctta tcaccttgcc
     9901 ttctgcttct tattactata ccccctttta ccttattaaa atcaaaccct ttagatgaat
     9961 tgtctaattt catactctta tacctatcta tgctcattac ttgggtctca ataatttgtt
    10021 ttaattcttt tattttaata aacccattac taggtacatt gtaataaaat tcaatttcct
    10081 cattaacaat ttcctcattc gttaatatta tactgtcttt ttttctataa acaaatatat
    10141 ttcttggaag agttaacatt ttatttactt ttgaattatc ttctaaagac attatatcct
    10201 ctatatgtct ttggtcaaca aaattagtat ctcctagtat atgttttatg gaatttctaa
    10261 gaactctaac tttgatagca tcatgtaagc aaacaaaatc gtctaaattt atctctacaa
    10321 atcctttttc ttttatattt gaaacttctc taaatttagc ttctgcctct ttctcaatat
    10381 aatcgttatc actttttaaa ctattgctca tcctcactat agattctatt acatttgaat
    10441 taaaattatc cttcatatat ggtaaaaggt ctaaccttat cttatttcta gtgtatatat
    10501 tttctaaatt tgttttatct atcctcggat ttaaattata agcttcacaa tactcctcta
    10561 tctcatttct ttccacgtct aatatgggtc taattatgca attatctcta atataatcaa
    10621 ttccctttaa accttttaaa cctgttcctc tcatgatacg catcataaca gtttcggctt
    10681 ggtcattgag attatgacct attgctattt tattggcttt aatcttatcc ttaatttcat
    10741 aaaacatttc atatcttagc ttccttgctc cttcttctaa tgataatccc tcattttcac
    10801 aatattttgg tacattaata gactttacaa agaatataat tcccatatcc tcacaaagtt
    10861 tagatacata taatgcatct ttttgagctt ctatccctct tatttgatgg tttaaatgtg
    10921 ctgcatatat ttctatatta aaatcttttt ttaatctatt tagtacatgc aataaacaaa
    10981 ctgaatcagg tcctccagaa agacctaaaa ctattttatc gcctttttgt attaaattat
    11041 gtttatttat agtacttagt accttatcaa atatcatatt tatccctctt acacttagtt
    11101 ttattcactt ttaagtatac tttctataaa aaaacgctaa acccttgtat caattttaag
    11161 aaattaaagt ttaatataaa tataataata ccaaataaat taaataaaag gtagtttttt
    11221 cactaccttt ataaaatttc tggaaaatag ccatagttat tatttagtac ctatgtatat
    11281 atctatttta ttcctaccta aaaataaatc ttgtaccttt atattatagt ctattttcaa
    11341 ttttatgtgt tccccttctt gtatatttat atctaattct cttgtatcaa tatcaattaa
    11401 taaagtacct tgtggggtca cataccttgt agtactactt tctccacatt taaacagcat
    11461 tgttgagtta atagcaccaa actttttgat actaacttga tttttaagta tctttatagt
    11521 attagttatt tctatatttt cttctttttc cttgtaaata acatatattc catcattttt
    11581 ataaaaaatt ttaccaaagg cagtcatctc tatggtgtcc atatttcctt tttcatcata
    11641 ttgtctagta tttatactta tttttacact caacgatttt tcctccatag attcttcata
    11701 taaactagta tttttgtatt tctacttttt gaatcttatc aatttttttc tttaagaact
    11761 ctcttgctat atctgaaaat ttttcatgta tatctgatac ataatattga taagttccat
    11821 gaatttctgt attgtttata atattttgca cctctaaaat cttttttaaa tcctttgcag
    11881 tctctttagc tggattaaca agttttatat gctctccaac ttcttcacct attgttctct
    11941 ttaaaatagg ataatgagta catcctaaca ctaaagaatc tatatttttt tctttcaatt
    12001 cttgtaaata tatctttgct gtcaatttag ccacttctgt atttgcccat ccttcttcaa
    12061 caataggtac aaataaagga catgctttat taacaatttc tatactctca tctattttag
    12121 atatttccaa gttgtatgct tttgaactta tagttccttc agttcctatt attcctacaa
    12181 ttttattttt tgtagaactt acagctgttc tagctcctgc ttctataact ccaattatcg
    12241 gtatatcata tttttcttga gcttctttta agcttcttgc agtagcagtg ttacatgcta
    12301 taactatagc ttttacacct tttgttttta aaaagtttat agcttgaaaa gtatatttaa
    12361 ttatagtttc tttggatctt gaaccatatg gtattctggc agtatctcca aagtatatta
    12421 tatcctcatt tggtaatatc ttcattatct cttttagaac tgttaatcca cctaatcccg
    12481 aatcaaaaac tcctattggt ttattgttca tctttataca acacctactt tacatttttg
    12541 tgtttaacaa caacttattt atcgctaaaa tttatattta tattcataat taatatatta
    12601 ttacctaaat gattattata gtttatttta cacaaaaaat aaaggagcta tcttaaatta
    12661 gaaaataatt tctacaaaaa gacaactcct ttcactactt aaaaatttaa atttattttg
    12721 caaacacatg atttcctatt ctcatataag gattcaatct atttatccat ttgcaagtgg
    12781 ctatttctgg attccaaaaa tatactgctt tattagttgg gtcagttcca taaagagctt
    12841 cctgagctgc tttacgtgct gagtctgttg gtgccatctt tattgaacca tcaagcacaa
    12901 ctgagaaagc atttttttga tatatgactt cttctattgt gtctggaaat ctagggtcca
    12961 atactctatt tattactaca gctgctacag caacctgtcc ctcatagctt tctcctctag
    13021 cttctcctgc aaccaactta gataataaca tcaagtcatt atcagataaa tttattactt
    13081 ctttctttgc tatatttttt tcttgtttgt ttactttctt aatattttct gttggttcat
    13141 atgcaaatac ctctttaata ggcataaata taaaagtcaa agctaatagt gtagccatca
    13201 gtttactcca cctgtccatg attaaaacca ctccttacat tcttattttt aaaatttttt
    13261 ctctaaatcc ttgactactt caagtacttt aaacttaatt tttactctac ttgttttttt
    13321 tggtgtatct tgttttatta acttatattc tttatcagtt aaaacttcct tcaacttatc
    13381 atctgtagat ttatctatca ctccattaga ttcatcaaca aaacatagtg gagggaacat
    13441 aacacaccac cagttttttc cttcaccttt cccaatgata atctttaatg ctttatattc
    13501 accagctgga agaactatat tagaatattg tttagtaggg aaattgctat attgtatacc
    13561 tacctttaca ctgtaattat atccattttt aagaataata tttttactta tttcttccag
    13621 accactatat tcctttttta taatagcttc actttctttt atactttttg aattttgaag
    13681 ctttggctgt aaatatttta ttacttcatc tctaactttt agtttaagtt cttgatcttc
    13741 atctgtattg ctgtttgcta taacatgaaa tcttattaat ttatctttat aatcttttga
    13801 tatattgtct acttttttta cctcaccatt tattactatt gtcattattg atatgactga
    13861 tataagactt aatattaata gtcccaatct aatcttaatt tttctcattg aaaattcccc
    13921 ctcaagataa atttatatca tcaattatgt ccaattaaat ttaatttatt cataatattt
    13981 tttaatacta ataaaaaaag ctatcttaaa atgattacaa tcattttaaa atagcttttt
    14041 aaaccttata ttttataagt ctttactaat catagcctta tctatcataa actgctctgc
    14101 tttttctata tgctctgtag catacttctt ggatagctca ctatcacctt taattatagc
    14161 atcaagtaag tatttatgct cttcaacaat attatgtgat gtatcataag cagacatata
    14221 ggtaactcta aatctatata cttgttccca taatgagttt attagttgga ttaatttttt
    14281 attattagtt gctttaaata tacattcatg aaattctaca tcaagtttta ataacgcatc
    14341 tacatcggat tccaaagtgc tttttttaaa ttcttctgat atatctttaa gctttttaat
    14401 atcttcatca ctaattcttt cagcggcaag atatgctgct aagccttcta ggcttgctct
    14461 tacttctaat acatccataa tatcctttaa tgacatattt gccacatacg caccttttct
    14521 aggcaacata acgactaaac cttctaattc aagctttctt attgcctctc tcactggagt
    14581 cctacttact cctaattgtt ctgctagttg cacttccatt agcctttgac caggctttaa
    14641 ttttccttct aagattgctt ctcttaaatt ctcaaagact acatctctta atggcttgta
    14701 attatccaag ttcagtttag ttaaattctc cacaaatttc aacccctttt tgactgctat
    14761 taacaacata cacctgttta tattttttta ataattcttt ttttccaatt agagcatctt
    14821 ctttattttt aaatagtcca aaaactgtag gaccacttcc actcatcata gaacctaaag
    14881 cattattttt catcattact tgttttatat cacttatttc tttgtgttta cctatagtaa
    14941 cattttcaag aatatttacc atgctttctg atacagcttt tatatcttca gattttaaac
    15001 actctatcaa atatttatta tttggtcttt ttttaatatt attcaaatct aatccttgat
    15061 aaacttcttt agtagaaacg agtaagtctg gtttgcatat caatatattt gtatcacatg
    15121 gtaaaccttt gatgtttgtt agcttttctc caataccttg agctaaggca ggtcttcctg
    15181 atatacaaaa aggaacatct gcgcccaaat taagtcctat ttcttttaat ttatcttcag
    15241 ataatctaag ttcccatagg tgatttaaac ctactaatac tgcggctgca ttagaacttc
    15301 ctccagccat ccctgctgct acaggaatat ttttttctat gaatatttct acaccttttt
    15361 ttatataaaa tttattttta agtattttgg cagctttata aacaatatta tcttcatcta
    15421 aaggaatatc taaactagtg ctttttacct ttatttcatc ttcgtctaat tcttttatct
    15481 ttactatatc gtataaatct atcgtttgca ttatcatttc aacaaaatga taaccgtctt
    15541 gcctttttcc caagacatca atggataaat ttatttttgc tctactcttt agtcttataa
    15601 aatccattct atcctccttg tttaaagaat aatgcatcac taacaataat attatactac
    15661 aaaaaataaa ataatagggt attataatac cctattatac ttaattactt taaatttttt
    15721 aatattaatc tactaatacg actttttttt ctaaaataag acacttacca ggcttaattg
    15781 gttcatcaag ttttatatca ttaagttctg caatttcatt ttctgttgta ttgtattttt
    15841 ttgctatatt ccagaaagta tctccttctt tgcatatata tacgattatg ctaggagctt
    15901 tagataaatc atatacacct tggtcttctc ctttgataat aaaattttct gctttcttat
    15961 ctaatgcttc agtaaatctc ttaattttga taatcaagtc tatctggtcc ctattcaaat
    16021 caacttcgac tttatcaata catgctgtat taaacacaga tgctgtatca gttagattat
    16081 ccatttctat atcatgttca aatggaattt cctcactaat tttataaacc aattttaaac
    16141 cttcaactgg gacaaataaa atttcaactt ttatgattcc ttgtataatg cttttatttc
    16201 cttcaatata actattttct atagacatgg ttggacaaac gcttacaata tcttttattt
    16261 gtatatcatc attatcattt cttatgcctt ctctaaccat aaatgtttct tcactacgtc
    16321 ttaaagtctt atttaattga ataggtttgt ggtcaaattt tattatcttt tgaggcgaat
    16381 atgcatcttg taatacttct cttgtaactt catctgtaac ttttacctta caacaagcca
    16441 tacaatctat ttctaaaaga cctgtgttac tttcactatt ttgcttgaaa atatgattaa
    16501 aatctgacat agacaacaat acttcttcag tcataccatc actaactcca gggacttcta
    16561 caaattgggt aaactcaata cctactctat ccaactctac aagttcaccc tcatatgtac
    16621 aagctaacgg atttatttct aatactccac caataataac tttattgtca gtcactctac
    16681 tttcttttac tttaacacat ggatttaaac ttattataga ttgaatttcc tctgtgttta
    16741 ttgttatagt atctcttata gaactttctg ctttttctat tccaactata tcttgaaaac
    16801 aaatttcctt tctgtgcttt tgtatacctt ccacttgtgc cacatctttt acaatgtcta
    16861 acctttgctt ttcaaacaaa cttcccctta tattcataag agctcctact ttaatctttc
    16921 tctcattcat tatagtacaa tccatatgct ctacttctga aaataacatg tattccatat
    16981 cttgaataac attgtctttt tctattactt cgtttatatc tacttttccg tctacattag
    17041 aaatagtatt tttatcatct gcaatataga ttacattata attaaaacta cctctgcaaa
    17101 gtatcttccc atctgccatt tcaatttttt taagtgatat gtatccttct gtttttacaa
    17161 tttcatatac atctaatttt ttgtctggta caactgcctc cgcttcaatg aatgtttgaa
    17221 attttccaaa gtctattcta ttgtcaactt taattacatc tttaattaat tccatagtct
    17281 acctccttaa gtattataaa aatatcacac tatatttata tttaaggagc aaaaaaaaaa
    17341 ttacacctat ttttaaatag gtataatttt aacttatttg taatttatct tgatctctaa
    17401 aaacttgcaa ctttacatta gatgttaata aatctgagta actataagat actctaggat
    17461 atccattact ttcatcatct aactttataa caaacacgct tggataaact ttttctagta
    17521 taccctcttt tgtaataatc tgctttcttc ctttattagc tttcaacaat attttctttc
    17581 ctatatgtct ctctaagctt actcttatct tatctagagt ttgaacagta gccacaatat
    17641 caccttcttt aacgtttata tgtttacata atatcacata taaacatttt tgtcaaatgt
    17701 ttaaactaat tattttatat attttttgca aaaatgtcaa tactattttt gaagatatac
    17761 agtataatta tgttaatttt tgctaatgta atattgtttt tggcattgcc catctaaatt
    17821 ttcctcttgt ttcagaacca ccaattccct taacacctgt aatagtctgc tctataacct
    17881 catcaatagg aactactaca tcaattcttg aacaagcaat tttctccact ataaaaacag
    17941 ggtctaatgc atgtatcatt attcttccag gcgaacttgc ataatttgct cctgcactta
    18001 ttattttttc ataatttgat tggcatgctc ctgcgaatat gacaagatta tccaaatttg
    18061 gttgccattt acgtgcttct tttactgttt taacaaaatt tgaagagttt ctatagttac
    18121 tcatatcttc tatatctcct ctttttattg tcattgcatc atgacctgtt attactagta
    18181 tatccggatt atatttttct agtagtgctc ttacttcttt atactgattt tgctctgaaa
    18241 cagctacacc tactgcaggt attccaagtt gagcatatac atccaagcaa atttttaaat
    18301 attctttatc tccatctatc tgtagtactt ttccaggcat tccatatgtg ttcggattta
    18361 attgaagttt tggaactgct ctagtcattc ttttttgtct ttctttagct tttcttactg
    18421 acttatataa taaattttct acatttttat ctattaatat atcttttata tcaggtgctt
    18481 ttactaattc taggtcatca atataagcat ctgctattac tctaaatgca attcccttta
    18541 gtatagctat tttctcatta ttttcatcta caccaaaaga gactatttta aatactatat
    18601 ctttgttatg tgactttcta gctacaatgt ctcctacctt catagttaaa cctccaataa
    18661 atttttatct tagtttatac tatgttcgat ataaaacttt gtttcctaat gtcaaaaaaa
    18721 catttcttat aatacttctt ttatcactct taaagcattt ttataatata tcttttctat
    18781 atcatcttca ctaaaccctt ctttttttag aggttcatac agtttaccca tctgagatat
    18841 atcttcaatc tcaacttttg aatctattcc atcaaaatct gaccctaggg atacaacatc
    18901 tatccctcca acatttacaa tatgttttat gtgtctaacc atatcttcaa gtttactttc
    18961 acttttatca cttaaaaata agtggaagaa gtttatacct gtaactccac ctttatttgc
    19021 taatacttta atcatatcat cagttaaatt tctagaatga ttcatcattg ctcttgaatt
    19081 agaatgtgta gcaattattg gtttagaaga aatctttgca atttcataaa atccaccatc
    19141 tgaaatatga gaaacatcaa ccaacattcc caattcattc atcttatgta ccacttctct
    19201 tccaaaatca gtaagccctt tttctctata ttctacttta ttatgaggaa agctcaattc
    19261 attcacatga ttccaactta ttgtcatcat tctaacccct aagttgtaaa atttctttaa
    19321 attttctaat ttaccttcaa gtactgcacc ttcctcaata gataaaagag ctgtaagttt
    19381 accttctgat tggtttttca taatttcttc atagttagta gctaaagcta tttcatcact
    19441 attttttttc atttcctcat gaaatttatt tgccatactc atgcaataat caaaaggatg
    19501 ttttacttct tcagtatcaa caaaaagagc aaatgtttga gctaatgaat cccccttttt
    19561 caatctgtct atatcaacag aatatttatt agacttaagt tcacttgttt ctacattttc
    19621 cattaatttt gctatagtat cacaatgtaa atcaataaat ttcatattta taccccctgt
    19681 atattttata tttatatcta aaaatagaaa tagttgtcct tatagacaac tattgacaac
    19741 tattttttaa tattcttttt aatattactt aatcttattc ttcttttaag ttaggtatta
    19801 cttttttaac ttcttcaatt tgatgccatg ttttatctat attattttca ctaatatatt
    19861 tttttaaatc agttaaagat gtaaaatctt taactgataa attgtcatca tcatctgcaa
    19921 atcttaaaat aaacatgaga ctcccttact ttccacaaca tttcttatat ttttttccac
    19981 ttccacatgg gcatgaatca tttcttccta tttttgcttc tttaactatt gttttagact
    20041 tcttataagc ctttattatt tcttttcttt ggtctgctgg tagtatatct tcccaacctt
    20101 gtaaattata tagccaatga gcctcaacag ttaccatatt gttatataat ttttcccaat
    20161 ctatttttat agaaacttct ttatcagctt ctacttcttc taaaactata tcttctttta
    20221 agctttcact tattccatct atgaatccca tgaaaaattc attagtagtt ccaaattttt
    20281 cagccaattc acttacttta ccttcaacaa catccatttt attatttaat atttcattgt
    20341 atattccagc ttcaactttc aaatattctt cccagaattt tacttctgct tcttgacttt
    20401 catgattatc acttaaattt ctccattcag tatataaact catacttttt cctcctaagt
    20461 atacctatat ttttatagtt tttatagtat aaaatctttt agttagattg gaagtttctt
    20521 ctttttgatt ataccatatt ctatttaaag ttaactctta tattatatca taattaaaca
    20581 attcttttaa tacttttata gcatactctt ggtttataaa ataagggctt gtcgcaattg
    20641 ttattacttt ggctttttta attaagtttt ttatcttgta aaatttgagt tcaaatggta
    20701 tatagtccat atcacttgaa aatatatcca aatctatatc aagaacaaac tctgattcta
    20761 cttctaaatc aaatccatac agactatcta ttattattaa ttctgaaaat atgttatatt
    20821 ttaaagcagg ttttataaaa cttcccacat ttaaaacttc atttgtatac ctaaatacat
    20881 cttttagatt atttacatct acatcatagt tctcaggctc tctagtatcc ttatgttggt
    20941 ctacatgcac taacttgcat ccttttgtaa attcaccctt taacaaagat tttgcccaaa
    21001 aataaaatgc atggttatga ttgtcaaaca catatatctt tttatttccc aggacatatt
    21061 cgaccatatt atccaatcct tttgctttta tttccttatt ttcatctact tcattaaata
    21121 ccacctcatt gcctaacctt acatcattta atgtaccatt tataagtttt ggaacgtata
    21181 tgctcttatt ttctctttta tcatatgaaa atacattatt tcctactggt ttttctatat
    21241 aaaatccact atattcataa ttttccataa aactttattt cctccattgt tatataaata
    21301 tataagttat aattttaaaa attaaaatgc acttattgta aatcatatta tctattatag
    21361 aaaacatctt atataactaa atataatatt ttctctcaat atgtattata caataagtgc
    21421 aaaatatatt tatataaaat atactacatt cctataacaa aaccatcagc ttcaattgga
    21481 aggtaactaa ctcttctatt caactccacc tttccaaaaa atactaccca atatggtcta
    21541 aaaatacttt caattttaac tatttcaatc tctgggattc ctcccataaa cctatgaatt
    21601 aatctcatag ccattttatt tgcctttgct tttactcttc gttcgtcctt attactatac
    21661 tgcacaatat tacaatccac attttttaca atttcatatg taggaaaatc ttgtactata
    21721 ctaccagaac ctgtagaacc attcactaaa atttttaatt catttatatc attagaatat
    21781 ctcctattct tgaaaatgga tttcgttttg tgaattttaa gtgtgataat tttaaactct
    21841 atataatgaa gtctaacttc atgagcatat ttgttcttta atattagctt actaaataaa
    21901 gaatttttcc cacttttagc tatctctata gcttcttctt ttgtaattct tataggtaac
    21961 gctcttatat ccataaaatc attctctttc ttattttttt cttgtcattt ttaaaactct
    22021 atatatataa tcaaaaaata ttacaattac aactgccata actccatatg gaattatttt
    22081 tccaactata atatcatttc tagtcaatat accataaaat ataaatcctg ttattaaaaa
    22141 gtacaataat actagaaaac cgtctattcc aagccatttt atttctaaat ctttttttac
    22201 cttagacact aatttagaca tagcagtttc tccttttata gattattttg tatatttaaa
    22261 tcttcaccta ttctattacc aatcatccat gcaataaatg aaaaaggtat agctatcaca
    22321 agaggctcta actcaaagct ctgaactgga aatattttaa aataaccaaa agtcactcca
    22381 cctacaatca ttcctaaaat accacccata gatgttcttc ttccatttcc aagaagccca
    22441 cctactatag gtacaaatgc cgaacccatc caaatacttc ctacaaatat acatgcatca
    22501 tatacatttt caaatctaaa tgctacgcta agccccataa ctgctgctaa acatacacct
    22561 attctagtaa actttactaa ttgtttctga gataactctt tttttgtaat tcttccatat
    22621 atatcatttg ctaatgtagc tccagctgct agataatagc tatccaatgt tgatattata
    22681 gaacctaaaa ttcctattat aaatattact cttattcctt gtggtaatgt atctaaaact
    22741 aaagttatat atccagcggc tggagccatt tctggataag tagctcttac tataagtcct
    22801 gttatagtta acaccatgtc aaaacatatc catagtgaaa aacaagttaa taaggctctt
    22861 cttccaacct taggagaatc tgctgctgaa aatctttgat aaaaagttgg gtctgaataa
    22921 gctccaaaag aatatacaat taacatcaat gctttcatag ctgacatacc ttttgtaggg
    22981 tgcataagct gtggtgcatc tttgagtgct tctgtgagac cttgaaatcc tcctatttgt
    23041 tcaaattgac ctggcataac catagttaaa ccaaatacca tacaaaaaaa caataccata
    23101 tctgtaatgg caactcccat aagcccacca agtactgtaa gtacaacgac tactcctacc
    23161 attattaatc ctattaattc tttatctatt ttccatgcta cgttacctat agttcccata
    23221 gcagttattt ctccaagttg tgcacaatat ataaacatca aaattgcccc aattatagca
    23281 acatgcttgc cataaaaact ttccagtaaa tcaggaactg ttatattggt tcttatatga
    23341 atccttggac caacccacaa tgctaaaggc attctcccaa tatgtgcagc tattgaccaa
    23401 actgcccatg cagatattcc atatatagcc gcatactcta cactacctac tgtaccaact
    23461 cctccatacc atgatgcaac caaagttcct actattaagg accatggtaa acttcgattt
    23521 cctaggtaat aactttccat atcttttaca tttctagaaa aataataacc tattcctaat
    23581 aatataaatg caaatataac tataatccca ttttcccaaa atgttaacat atctaatctc
    23641 cacattctta tattttaatt tttaacttta atatctaaat atgaacaact ctacccattt
    23701 ccataaaaat aggtagagtt atataataat tataagtatt taagtaatct tgttattaag
    23761 cgattttatt gtttaaaccc ttattttctc ttttatttat tttatttaaa gcataagtag
    23821 caaatattcc tataactgca catactacag ataaaataaa tatatatgta tatcctgttt
    23881 gtccatattt atctaaccaa ttacctgcaa tagtgtaata aaacgcatct ggagaaaatc
    23941 ctataaatga agcaaatcca actactgctc ctgtagtttc taaagatata ttagactctg
    24001 aaacagatgc aaagtatata cctctaaatc caaataaaat tacacttagt attatcatgt
    24061 ttattacagc tatccatata aatcctgtac tcttaggaat aaccaagtaa gcagctgtac
    24121 ttactgtcat taatataaat cctacaaaca ttactcttat agatgaacca actttatctg
    24181 ttataacacc agcaactgga gatgctccca tttttataac ataagttctt attattgata
    24241 aagcagaaac tagagtcatt ggcattacat aaacttctga taagtatgga cttaaataag
    24301 ttaaacttga gaatactaaa taagttgaaa atattataag accaattaac caagcctttg
    24361 gcattgtaac tacttttagc aatgacttaa tacttaatcc ttcatctgat gctccactat
    24421 cttttttctc ttctactaag aaaaatagaa gtataccaca tattatagat gctgcagaat
    24481 ataaccatac tacatatttg aatcctactg ttatttcagc aaatttacca aagaagtaaa
    24541 gacctataaa agaaattaac gtacctgata cacctgataa cccttcataa aaaccaaata
    24601 ttcttccttg ttctgactca cttccttgca ttctaacaac cttaacagaa gctgagaaga
    24661 aagttaatat tgttgtaaat ccccataata caaatattaa aagtatcata ctatatgatg
    24721 ggaatgtaga gaaataaaaa ccaagtactc ctgaagcaat taaagaaaaa gttattagtt
    24781 ttctaactga gaatctatct gcaaaccatc ctcctataaa ataagatatc attcctacta
    24841 atccatataa acttaataag ttccctattt gtgtatgact taatgctaaa gcttgttgca
    24901 ttgggtcata aaatgatgat ttcatatatg gtaaactata catagctgtt gttccaaatg
    24961 ccaatatgaa tattatcaaa aatcttttaa cattattttt gctttccatt gattctctct
    25021 ccttaaaatt ttattgttta taatctcatt catgtaattt tattttaatt tttttattgc
    25081 ttgtttaaag tcatttatta tatcatttga agattctaat cctacagcta ttcttattag
    25141 attttctcca ttcatttgaa ctaatgtatg ctcttcccct aagcttgttg ctattgttgc
    25201 aagctctaaa gagttcatta attttctact agcttggtct cttgtcaatc cattgatacc
    25261 atccttaagt ttaaatgaaa ctacacctcc acctaaacca ttcatttgag ttttacaaag
    25321 ctcatattga ggatgagatt ttaatgctgg atactttacc aattccacat tctcttcttc
    25381 ctctaaaaac tctgctactg ctaatccatt ttcacaatgc tttttcatcc tcatatctaa
    25441 cgttttcata cctcttaaaa tcatccatgc actcattggt ggtaaagatg ctcctgtaaa
    25501 acaacataaa cttggccatc taactaaatc tattaattct tttgaacctg ctactgctcc
    25561 ccctaaagta tccccatgtc catttataaa cttagtaaga ctatgtatta ctaaatctgc
    25621 acctaaatct attggtcttt gtacaattgg tgtcccaaaa gtactatcaa ctatagctaa
    25681 gcttttattt tcatgagcaa tttctgctat tgtttttata tctactaagt ctaatgatgg
    25741 atttaaagga ctttctatat aaactatttt agtatttggt ctcattgctt cttttacatt
    25801 ttgtggattt actgcatcta caaatgtaac ttcaactcca aatttagata acaactcaga
    25861 catgaataat ttagtgtgtg aaaatattcc atctgaacta actatatggt caccactttt
    25921 taccaatgct aatatagtgg atgttattgc ccccatccct gatgtactag atatggcact
    25981 ttctgcattt tcaagcatag ccaacttagc ttctaactct gtaagagtag gattacactc
    26041 tcttgtatac acatatcccc atgtcataca caactcttca aaatgctcta ctgtctttgc
    26101 agcaaatgtt gctgtttgac atattggtgt agccaatgca cctgttgttg ggtctgcact
    26161 atgtccccaa tgtattattt ttgtctctaa atcttgatta atattgttac tcattttgat
    26221 ttcctcccat tttgacttat ttatacaacg ttttccctgc caaatttaat caatttagct
    26281 tagtcttaat acattttttc aagtatactt ttttatttgt tataatttct aaaaatatga
    26341 cacttatttt gtttttttac agttctaatt ataaactcta tagtaactat agagtcaata
    26401 tgtttttgat atttttttta caatgtttaa aatagtcagt acaaaaatag gtatatctta
    26461 gaataactaa agtcatccta agatatacct atttttatat cacaatataa ataattacat
    26521 ataagcatta gtttttttat cataaataga tttttcaaga tttatcatct tttcataaat
    26581 atattatagt taaatatttt aatattacct aacatctaca ataaaatata ctcttaaaat
    26641 aaaattatat aattaaaaat actctataaa agctaaaaag ttttctattc gctacatcta
    26701 aaaataatta gatagaggta taaatgtatt tagtttattt atacctctag tcttttataa
    26761 attatatctc tactaaattg attttttagc acgaataagt gtgctcttgg agataccagt
    26821 catcttcaca acctctctat atggcttaga atttaataac cccaatgcat attgtatctg
    26881 ttgattgctg tatttctttg gcctaccatc tttgaagtcc tttttctttt tagcaaattc
    26941 ttttcctaat tgagtacgtt ctattatcat atttctctca agctctgcaa ctgcaagtaa
    27001 tgtagtcaaa aagaatttac ccattgaagt attttctaaa agacctatat ttaaaatatg
    27061 aacacttact tctttagcaa ataaaccttc tattagttgt atcccttctg atgtacttct
    27121 agctagtcta tccagcttag ttgcaacaag taagtctccc ttttttagag atgatataat
    27181 tttttcaaat ttaggcctgt ttgtagtagt gcctgtataa gtttccttta ttattttagc
    27241 atcattatat ttattcaaaa tttcttgctg ttgctgatac aaactgttgt tgtctgtttg
    27301 attttttgta cttacacggc aatatccata tataataatc atcacttcct aacataaaga
    27361 ttttgtacag aagttaccca gaagcttgtt tttacttatc tttatccatt ttactaaaac
    27421 gatttttggg tgtcaatact gttaactttt gacaccataa taattccttt ataatttgtt
    27481 tgactatgtc aaaaattacc aatataatga aattaatgag tttatacaaa ttggaggaaa
    27541 taatatgaat agtctgttaa aagaagcaat agatgaatta aaaaacatcc attgcgggga
    27601 agttttttta ttaaaagaat tgttcaaagg ctatgaatgg aacaggttgg agatgaatat
    27661 tagattgaaa ttaggaaaac tttttttgta tgaagtggta actaatccca atttaaatgt
    27721 agaggtcatc aataaaaatt ctgcttatca gcaaatgtat aaaaaaaaat agtgacttaa
    27781 atgtatataa tagtataatc ttcttattga ttcaaaagtt aaaactttta atacaaaaca
    27841 atcattctat tttaacattt atcaatatgt ctaaatttat ataattaaca catacgaata
    27901 gtattgttta aatcacatta tttaagatag ataaatctta accctactcc agcataaata
    27961 ctaaaatagg gcttagaatt atctatattt ttatcccata aaatgcttag ctcttcctct
    28021 tgattgaaca tatatatctg gggaaataca atagaagcgt aaatttataa aatttccaaa
    28081 gtcagaaaac ttcagttcaa acttaggtat accaaaactt tcaggtgcta tttcgtcaac
    28141 gccaaaatag atgataattc cattatctgt aatataaaat gcttggtctt caggtataac
    28201 taactcaaca ttagaataat acatttctct attttcattt atttgagatt taatgtaatc
    28261 agtaattata ttaatataat caactccatc tctaaaaatg tcattaagta aaagttcttt
    28321 tccagttgtc aaatctatat tgtaattatt caatgtattg tatttaggcc catagttatt
    28381 agcaaacccc ataaggttta atatcatact cagtacataa tttttattaa aagtaactgc
    28441 gtaactggta gatacccaat agctttgttt tggaagtgaa ttttgagaag ctgcgttatt
    28501 atgttctcgt tcttcttcct gtaagccatt tttaaaatta tttacagtca ttcttacagc
    28561 attgtttatg ttatttaaaa taactgggtt tacatacgtg gattgatttc taatattgta
    28621 tataacagga tactttacat catatgaaaa atacttactt ctttcaaaat cttcattaaa
    28681 ttgtacatat aatatattat atgtacaggt atttgtagat tgataatttt ccattaaaat
    28741 cctccccctt ttataaaaaa atcagataca atataatatg cttaaaacag taataatgtt
    28801 aatagtaaat gtaaagaata gaaagtatct aaaacagcaa aaaatgacta attttgtggt
    28861 ataatacata ggattgagag ttattttata ggaggaaaaa tatgttatta ttagcagata
    28921 aatggaaaga ttatgaactt atagatatgg gaaatggaga aaaattagaa cgttggggaa
    28981 gttatgtact tagaagacca gacccacagg ttgtatggcc aatggaatct gaatgggctt
    29041 tatggaaaaa ccctcatgga cattatcaca gaagcaataa aggtggaggt caatgggaac
    29101 acaaaaaaag atatccagaa caatggacta taaattataa aaacttaaag tttcacatta
    29161 aaccaactgg gtttaaacat actggattat tcccagagca agcagctaac tgggattgga
    29221 tgatagagaa aataaagaaa gctaacagac ctataaaagt gttgaatctt tttgcatata
    29281 caggtggagc tactgtagca tgtgcatctg ctggtgcaga agtatgtcat gttgatgctg
    29341 caaagggtat ggttaattgg gcaaaagaaa atatagaatt atcaggtctt aaaaatcaaa
    29401 cagtaagatt tatagtggat gatgttgtaa agtttgttga aagagaaata agaagaggta
    29461 aaaaatatga tgcaataata atggaccctc cttcttatgg aagaggtcct aaaggagaag
    29521 tatggcaaat agaagaaaag ttatacagtt ttgtggattt atgtatggga gttttatcag
    29581 ataacccttt atttttctta attaattctt atacaacagg attttctcca atagttcttg
    29641 aaaatgtatt gtctacaaca ataggtaaaa agacaaatac aggagatata tacggtgggg
    29701 aattaggaat accagcttcc agagatggta agatacttcc ttgtggtata tttggaagat
    29761 gggagaaaaa ataatgataa aagtcatata tgaagataac catttattag ttgtagaaaa
    29821 accagttaac atattgtctc aaggagataa tactaatgat aaagatatgg taaatctttt
    29881 aaaagactat attaaaaaaa agtataacaa acctggaaat gtatatattg gtttaataca
    29941 tagattggat agaccagtag gtggagttat ggtgtttgca aaaacatcaa aagcagcatc
    30001 tagattgtct gaacaggtaa gaagtaagac tttcaaaaaa acttatctag ctgttgttca
    30061 tggcaagata aaatctaact cagatatact aaaagatttt ttatataaaa ataaaaaaac
    30121 taatatggta actgtagtga aaaaaagcca taaagatgcc aaagaagctg aacttaacta
    30181 taatgtatta gattttaaag aaaatctaag tttagttcaa gttaatttaa agactggtcg
    30241 ttctcatcaa ataagagttc aatttgcaag cagaaaacat ccattatacg gagaccaaag
    30301 atatggcaaa gaaataaata agattggaca acaaatatct ctttggtcca ataagataga
    30361 aatttgccat cctactacaa aagaaaaaat ggaatttaca tgtcatccac ctgacaaata
    30421 tccatggaat atattttaaa tctcaaatga ggtgattata tgagtaaaaa attttcaata
    30481 ggagaaatgt ctaaacttca taaaataagc atacagacac taagatacta tgaccaaata
    30541 gatttattta aacctgttca tgttgaccaa gaaagcaatt acagatatta ctcaattgac
    30601 caattttcac aattagatat tataaaatat ttaaaatatt taggtatgcc tttaaaagaa
    30661 attaagtcaa agcttgatga aaataatgaa gaaattctaa aattactaac aaataaaatt
    30721 aatatagtgg atgaaaaaat taaagaatta gagcttataa aaaaggtact aagcacaaag
    30781 aaagaaacta tggaaaaagg tatgaaagta gatgaagttg gtaaaatagt gagaaaacat
    30841 attccacgaa gaagtatctt atctatagag tatgaagaag gattaagtag tgaagaaact
    30901 atggaacttt ccagaagaca aatagcaaat atattagaag ataatatatc tgtgttctat
    30961 ggtggagtaa gtggacttgt atctatagat aaatttttaa aagaagataa agttatttat
    31021 gacaatagtt ttgttactgt tgaaagagac ttatttgata taaaatcaca aaaacatata
    31081 acagaaattt catctggtga ttttatttgt atgacatata aagggcctta caaagaaaat
    31141 tataccgctt ttaagaaact ggttgattat gttgaatata aaagaatacc tattgaaaat
    31201 tatatatatg aaatacctat aatagaccct ctgtctacaa acaacgaaga ggaacttcta
    31261 acagaaattc aaatacaagt taaaaagaga gaaattgact taagatgtct agtgtagtaa
    31321 tctagtttac ttacacatct taatatagtt gtctattatc aacatatgat ttttctagat
    31381 agtgattcct aacagtgaga ttttcaaaaa ataggaggaa acatggctaa tgctaattcc
    31441 ctcctatttt taattaatcc atatcatttt aattaagcca tgtcatcacg aagtgcatca
    31501 ataatatttt ctttttttat cttattaata gtatacaaca ttgtaataaa tactataaat
    31561 aaaacactaa atatactaat tcctatacta aaccatggaa tcacaaaatc gatatcatct
    31621 gtaaccatta ctttatgaat tagccatgaa gaaattactg ctataggaag tccaaagaac
    31681 aatgctctca tgccataaaa ggcacactca aaattcatca tcttttggaa atcatgttca
    31741 gacattccta cagagcgaag catggcaagt tctctacgac gtaacttaat attagttgaa
    31801 attgtattaa acacattggc aatcgaaatc agagaaatca taattatgaa agtataagca
    31861 aaaacattgg caataaaaat gtaattacgg ttctcatcca tcattccata catattgtac
    31921 agattgtact cattcgtaac tccctcactc tcaataattt gctccatttc tgcaactgac
    31981 tgagtaggat ttttcgattg aaagcttaaa ctttcaattc ctgtagaaac accaggaatc
    32041 tcaaacttat ctttggctga ataaggagcc aatactctga agcttgcttt cttcacatct
    32101 gaacttctga ttcctggagg agaatcaggt ggcactactt tgacaaatga aatatttaca
    32161 ttttgtctct caggtatctc caacttgcta ttagtttcag gagtgagact aacattcata
    32221 gaagaactgt tgaaaatatc aataatatta ttatcctttg ttaccataga aacagcaatc
    32281 agttttgcat tttgtccagt atattcttct gctggtaatc caagactttt aataatattc
    32341 agataagttc tatcatcaag aaattgcata tctactggta attcaagcat ttcactcata
    32401 gaatgtgaac cctcatagtt caaataatcg tctgtaagct cacttacttt ggcaacacat
    32461 gaataggtca taagtttctg atacaaacct tcgtaaacac catttgcagt ttttagctta
    32521 tcgtaaagct tcaacatttc gttgtctttc ataccttgtg tagaaaaaat aatatcctgg
    32581 tcagtaacct ctgacctctg atttgacatc tgttttaggt ctgctactaa agcacttgta
    32641 gatataaata aaactatgct taaaacaagc gacaatacaa tacttcgata acgtttcttg
    32701 tttcttttaa agtttttcat agcaagaact ccctcaagac cataaactcg ctgtgttagt
    32761 tttgatgtct tcacagattt agattcaatt tttacctcat ttgtctgacg aatacactcc
    32821 atcactggtg tgttggcagc ctttcttgct ggtatgtaag cagaaattaa gattgtaacc
    32881 atacctacca ctgctgcaac gatgattgca gggatagaca atgttaatgt caacggaacg
    32941 tttacataga gaatatttgc aaagttttta gctatgacag aaatcacaag tccaatactg
    33001 actataccga ttgcaacacc aattggtata ccaatcgcac caatgcaaat tccttcaaat
    33061 agcaccgaat ttcgtaactg ttttgctgta gctccaacag atgaaagtat tccaaattga
    33121 tgtgttcgct cgttcaatga catgttaaat gaattatata ttagaaaaat tgagcctagc
    33181 atgattatgg caagcacaat gccaccaacc gagtacaaaa acatattgaa caaattgtta
    33241 tcagaaacac ctatgaagcg caacacattg tcattgaaaa tggaagcatg gtctttagtg
    33301 ctacttgtgt aagagcgaat ctgatgtgga tttttcaatg tgacaaaaag gctaagactg
    33361 tcagtcttga cttgtttatc ttctttggtt atcaaggtat atcctggtgc agaagattct
    33421 tcaaatacgg gctttctaca gatacccaca actgtataag ttttcttatc ctgtggcaca
    33481 aaaacttcac tcccagcagt gtaggggtca ctctgaccaa gcttttcatt ttcactcatt
    33541 cgtttcccta catccaaaga aatggtatca cctactgcaa atttgacacc accatctgtc
    33601 gcaactttac ttgaaacaag aatctctcta ctattttcag gtaatcttcc agaaattaaa
    33661 gttataggca aagtatcaaa agcttctttg ctaaatccag caataaaaag atatggttta
    33721 tctggatttc tgttaccttc aagtgttgca tagccaatat tttcaaatgt tgcagtattt
    33781 gcaacttcat cattgactct ttgttcctgt acaaaagaag aatccacatc caaaaactgg
    33841 acatgccaat caccatattt tataatagct ccatttgtca tatagttcat caaagaaact
    33901 ccaaaggtag taactgctgt aatcatagca gctgacagaa caactcctat aattgttaca
    33961 agagttcgag tgcgattctt tttcaatcct tgcagagcaa ctttgttaaa aatgttcatt
    34021 aacgattcac cttcctctca tcacgcacta cttttccatc tgaaatacag ataattctat
    34081 ctgcctgtaa agcaatgttt tcatcatgtg tgacaataat gagagtttgg tgatatttac
    34141 tatggctctc tttcagtaac tggataatct cttgtccatt tttactgtct aagctacctg
    34201 taggctcatc agcaagcata actgctggtg cattcatcaa tgcacgacca atggcaacac
    34261 gttgctgttg gcccccagaa agttgatttg gtaaatgtgt ttttcgttct tttaaaccaa
    34321 gtaattctaa caagtcattt aaccgttctt gattgacctt acgcttatcc ataagtatag
    34381 gcaatgtgat attttccact acatttaatg tgggtatcag attgtgaaac tgataaatca
    34441 atccaacttg tcgcctacga aaaatagcaa gtttttcatt gctttggcca tatacatctt
    34501 gcccctccag atatatcttt ccacttgttg gtacgtctac tcctgcaatg gaatgtagta
    34561 gtgtagattt accagaacca gaagaaccaa tgattgcagt aaactcccct ttttcaatag
    34621 taagtgagac atggtcaagt gcagtaacct tattttcatt cttaccataa accttacata
    34681 aatcttcaat ctttaaaaac gccattatat aagtctcctt tcatatttta taaatatatc
    34741 ataggacttt caacttacat ttaagtgaca tttaaatgag agattcgtca ctttggaaaa
    34801 cgaataacaa atattgcacc accttgtggg tgattttgtg cagtaattgt tcctccttgt
    34861 ctcataataa tcgtcttaca aagtgccaat cctattccat aaccagctgt gcttgaattt
    34921 ttcccacgat aaaatctgtt aaatagacat ggtaaatctt cttttttaaa gcctgctccg
    34981 ttgtcatgaa tagtaagttg agtaaacaaa aagttgtcct cacaaacgat attaattttt
    35041 ccattatcac ccacactctc catgcagttt ttaaatatat tttgaattgc ttctgaaagc
    35101 caatttaaat cacccaaaat ccttactcct tttggtatat caatatgtaa agtgatattg
    35161 tgcagttcca tgggaatcaa aagttgatga agtgcagaac taatcaaatt actcacatca
    35221 atttgttctt tttgaaagac tacaatacct gcatctaaac gtgataattt taaaagggaa
    35281 gtaatcagcc agtccattcg tataagtaat tcctctgttt ctcgtatcaa ctcttttctc
    35341 tcatcttcat cagaagtatt ctctaacagt gacaaaataa gagttactga tgtaagagga
    35401 gtgcgaagct ggtgggctat gtcagctagt gaatcagcaa ggtgttcttt ttcttttttc
    35461 agtgcgtaat tttgctctct aatacgtaac gtcattttag ttatttcact ttgcagaata
    35521 gaaagctcac cctcatctga ttcagcaata tacagatggt tagcattatg aagcacaaga
    35581 ttaatttgtt ctgaaatctg tgcaatactt ttgtatcgat ttttagtaaa cacaaaaaat
    35641 gctattccaa aggtagtggc agaaacaata gaaagtattc cagtcataat actgattgca
    35701 aatcccaggg ctacagtgag aatagtaatt aataagaata aaatagcaaa ttttcgaaac
    35761 tctctatttc gaaacataac ttccccccaa tctataccct gtcccacgaa cagtcaaaat
    35821 tatttgtgga cttgaagggt catcttctat cttctctcgc aagcgtttga tgtacacagt
    35881 caatgtgttg tcattaacaa actcacctgc cgcatcccac aattcatcaa gtaatcttac
    35941 cctcgtaata atacttttag gattgctaat aaacaccaat aacaaacggt attctaaagc
    36001 tgaaagaaaa acctcattgc cattcttttt cacaacaccg gttgccgtat ctacataaag
    36061 cccacaaatt tcaaaagttg acccaaaacg cccacttttt cgtagtgctg ttctaattcg
    36121 cgcaatcagt tcacgtggac gaaaaggttt agtaatatag tcatctgcac ccatattcag
    36181 tccagtaaca acacttgatt catcaccaga agccgtcaaa aagataacag gaatgtcttg
    36241 cttttctttg atttctgtgc aaatcgtaaa cccatttcca tcaggtaaag aaatatcaat
    36301 aagtgccaaa tcaaatttat tcttagcaat ctctacaagt gcttcacttc ttgtggatac
    36361 atgggttact ataaatcctt ctgaattaag caaaagaata agatttttgg caattgcttt
    36421 atcatcctca actaaaaata tccgtttcat ttactttcat cctcctttat tttattagtt
    36481 ttatatattc cagcagagca atagtacact actattttac ttatcattac acaattttca
    36541 gtagtttctt ttgttcttat ataatccatg cataatacct ccattgattt attatatttc
    36601 ttataacaga aatacacaag ataagacaaa aaacataatg taagtgcaag ttttttaact
    36661 cactaactta taaacataca ctcctactaa cactactttc ttgatgacac atcttacaag
    36721 cttatattca tacatcaatg aaaaattaaa tttatccatt tattaaaata aaaggcaata
    36781 gcttctatag ctaatgccct ttatcttaaa atgatttaaa tactatacaa tttttataaa
    36841 tggctataaa taaactcgta tagaatataa aatttatcta cagtcttttg ttatacaaaa
    36901 tttataacct cttatagaac aaatttacca ctttgtaaac ttatcacttt tactcagcta
    36961 tattataaac ttttaattta tctttgttta aatgtttctt cttaacttct actaaagctt
    37021 ttagcgtatc caaagatgtc attatttcag tagaaaattc aatggctgtt cttctcattt
    37081 taaagccatc tcttgtagag tcatttcctt tagttggtgt atttattact atatcaactt
    37141 gtttatttct tatagcatct aatatgtttg gtctaggctc ttcaattcta tttactatat
    37201 cagcctctat tccattttct cttaaactat tagctgttcc ttctgtagca acaaaagtat
    37261 atcctaattc tttcatatct tttgctatct ctataaactc atctttatca tgattattta
    37321 cagtagcaag tactactcct ctttcatcag acatatgtct acctgctgcc aagaaccctt
    37381 tatataaggc ttcttctaaa ttttctccta cacctagaac ttctcctgta gacttcattt
    37441 caggtcctag acttacttca actttagata atttagacat tgagaatact ggtactttta
    37501 ctgatactaa ttttggctct ttgtaaactc ctgtaccata tcctaaatcc tttaatttag
    37561 ctcctaacat acacttagta gccaagtcaa ctattggtac tccacttact ttacttatat
    37621 atggaactgt tctactagct ctagggttaa cctcaattat atataattca ttttgaaatt
    37681 ctataaattg tatattaacc ataccaagca cattaaggtc taaagctatt tttttagtgt
    37741 attctactat cttttctttt atttcatcag atatattttg acttggatac attgttgtac
    37801 tatctccaga gtgaactcca gctctttcta aatgttccat tataccaggt atcaatatat
    37861 cttccttatc acatatagca tctacttcta tttctctacc agttagatat ttatctataa
    37921 gtactggatt tttatggtct ctatcaaatg catcatccaa atactgaatt agtttttctt
    37981 cgttataagt tatttccata ccttgaccac caagtacata agatggtcta actaatactg
    38041 gataacctaa ctccttagca acttcaatgc cttcgttaag tgaccataca ccttttcctt
    38101 ttggtctatt tatatctagt ctctctagta aatcatcaaa tttttctcta tcttctgctg
    38161 catctatatc tctaaagtct gttcccagta taggtatatt tttttcatgt aaaaacttag
    38221 ccaattttat agctgtctgt ccaccaaact gtagtattac accttctggt ttttcttttt
    38281 ctattatatt taaaacttct tcttctgtta atggttcaaa atacaactta tcagatgtat
    38341 caaaatccgt acttacagtt tcagggttat tgtttacaat tatagtttct attcccattt
    38401 ttcttaaaga ttttacacag tgaactgaac aatagtcaaa ttctatacct tgacctattc
    38461 ttattggacc agaacccaat actacaactt ttctcttatc actaactact acctcatcat
    38521 attgttcata agttgaatag taataaggtg atagggcttc aaattctcct ccacatgtat
    38581 caaccatttt ataaactggt tgtatattat ataaacttct caattcatat aatttttctg
    38641 ggcttatctt cattaagtca gatatacctt tatcagaaaa tccctttttc tttaattcat
    38701 gtaaatattc tttatctaag tcttctattt ttagaacttt taatttttct tcttgttcta
    38761 ctatccattt aaatttattt ataaaccact tatcaacacc agttatttct gatatcattt
    38821 ctactttata gcctcttctt atcatttcag ctaagtcaaa tagtctctca tcatcaggta
    38881 ctactactct agcctttaat tcttctaatg ttctaccttc tgatggagca tgaaccaatg
    38941 aatattttcc tgtttcaagt gatcttatcc ctttaagaat agcagcctca aagttacttc
    39001 ctatactcat gatttcacca gttgccatca tcttagttcc taattttcta tttgcatgtc
    39061 taaatttatc aaatggccac tttggtattt ttactaccac ataatctaat gttggctcaa
    39121 aacaagcata agttttttta gttactgcat tttctatctc atccaaagta taacctaaag
    39181 ctatcttagc tgctactttt gctattgggt atcctgtagc ttttgatgct agggctgatg
    39241 acctactaac tcttgggttt atttctatta tcgcatattc taaactatgt gggtttaaag
    39301 ctatttgaac gttacatcca ccttgaacct ctattgcatt tattatgtct attgatgcct
    39361 ttctaagtag ttgatactct tcatcactta gagtttgact tggagcaaca actatactgt
    39421 ctcctgtatg aactccaact gggtctacat tttccatatt acatacagtt atacagtttc
    39481 catttccatc cctcattact tcatattcta tttctttcca accttttata ctcttttcaa
    39541 gaagaacttg tccaacagga cttagctgta gtccatgtga aagtatttct cttaattctt
    39601 cctcagtatc agctatacct ccaccagttc cacctagcgt atatgctggt cttacaacta
    39661 ctggatatcc tatcttattg gcaaactcaa gacctgcttc taaatttgta actatatcac
    39721 taactattac tggttgattt atttctttca ttacttctct aaataaatct ctatcttcgc
    39781 ccttttttat agattctata gatgttccta taacttttac attatattta tctaatatac
    39841 cagcatcatg taattctaca gctaagttta atcctgtctg accacccata cctgcaagta
    39901 aactgtctgg tctttctttt tctattattt tttctataaa ttctattgtt aatggttcta
    39961 tatatatttt atctgcaatt tctttatcag tcattatagt agctgggtta ctatttacta
    40021 atacaacttc aattccctct tcttttaatg cttggcaggc ctgtgttcct gaatagtcaa
    40081 actctgcagc ttgacctatt attattggcc ctgaccctaa tactaaagtt ttctttatac
    40141 tatctaattt aggcataact ctttctcctt atctaaacaa ttttcacagt tcttatcttc
    40201 atcatctata caatcaactt taattacttt attttatctt aagttcaaat ttactcatca
    40261 atacatctat ttaatacatc tatgttaatt aaaccaaact ttttgattta agttattctt
    40321 gttttttagt tagctattct aatgttattt attttactaa ttctaaaaat ttatcaaaaa
    40381 tatagtcatt atcttttggt cctgggcaag cttcaggatg gtattgaaca ctgtatacat
    40441 ctaacttctc atgtctcatt ccttcaacag tattatcatt taaatttata tgtgtcactt
    40501 tcatttgttc aggaacttct gaaacataat aaccatgatt ttgagaagtt ataaatactt
    40561 ttccttcttc taaatcttta actggatgat ttccacctct atgcccaaat ttaagtttag
    40621 cagtttttcc tccaagagct aaagctaaaa gttgatgtcc taagcatatt ccaactatag
    40681 gttttttacc aataagagct tttatatttt ctataacatc ttctaggtct tctgggtctc
    40741 caggtccatt tgacaagaat attaagtcag ggtttatact caatacatct tctggagatg
    40801 ttgtagctgg aaatattgtt atatcacatc cacgagctat aaatgatctt aatatatttc
    40861 tttttactcc aaaatccata acagccactt ttgtaccatt tccttttata tgctctactt
    40921 cttttcttgt aacagttcta actgcttctg tatttgaaaa cttatccaat ttatgtttaa
    40981 catcttctaa tttactgtct tctaatgtaa ttataccttt cattgttcca ttatttctaa
    41041 gtatcttagt caaagctctt gtatctattc cttcaagtcc gataacttta ttttgcttta
    41101 aatattggtc tatatcaatt tcacatctaa aattacttgg agaatcactt ttctccctta
    41161 ctatgaatcc ctttacttga actttttcag actctgctga tgataaattt ataccataat
    41221 ttcctacaag aggataagtc atagtaacta tttgaccata gtaagaaggg tctgttaaaa
    41281 cttcaccata tcctatcatc gaagtattaa atactacttc tcctacactt tcttctaaat
    41341 atccaaatgc ctttcctata aaaactgttc catcttctaa tattaacctt gctttcatac
    41401 tacagtacct cctataattc tctttagaca aactaaagaa cattaactaa atataagctt
    41461 ttaaatatct atatctattt tcacttttac attctagttt tatacttatt tacatttatt
    41521 ttttatcttt ttctattata ctacaaattt cttaaaaaaa agaagttatc tcaaaagtaa
    41581 aaactcctag aaaaaataac ctcttttttt ttatttaata attaaattct taaactatac
    41641 aatcaactta atttctattc agctatattg taaactttta actcatcttt atttaaatgt
    41701 ttcttcttaa cttctactaa agcttttaat gtatccagag atgtcattat ttcagtagaa
    41761 aattcaatag ctgttcttct tatcttaaac ccatctcttg tagagtcatt tcctttagtt
    41821 ggtgtattta ttactatatc aacttgttta tttcttatag catctaatat gtttggtcta
    41881 gattcttcta ctctatttac tatatcagcc tctattccat tttctcttaa actattagct
    41941 gttccttctg tagcaacaaa agtatatcct aattctttca tatcttttgc tatctctata
    42001 aactcatctt tatcatgatt atttacagta gcaagtacta ctcctctttc atcagacata
    42061 tgtctacctg ctgccaa
//
LOCUS       DACTZW010000032        38803 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.032, whole genome shotgun sequence.
ACCESSION   DACTZW010000032 DACTZW010000000
VERSION     DACTZW010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38803)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38803)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38803
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.032"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            336..1172
                     /locus_tag="JAM15_08860"
     CDS             336..1172
                     /locus_tag="JAM15_08860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAT6798357.1"
                     /translation="MNIKKIFNNNVVVSSLEDGTEIIVTGAGVGFKKKVGDLIDENLI
                     SKKYFVQDDQRDKYNQILNKTSIEYFKISEEIIEKANEVLNTQVNDSIILALTSHIEF
                     AVQREKQGIKLPNLILNETKQLYREEFKFGLWAIDEIEKRIGIKLPEDEAGYIAIHII
                     NGLENSQKDEGINILEFSKQVIQIIEEVHGFKLDVNSLNYTRLITHLKFFVQRILRKE
                     TYNDSDIEDMYKLVNKNYNKPKVCTEEIAALVLDRFEYKISKEEELYLMIHINKITNS
                     GC"
     gene            1524..3101
                     /locus_tag="JAM15_08865"
     CDS             1524..3101
                     /locus_tag="JAM15_08865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAT6798358.1"
                     /translation="MKKNKLGLWNFFQMLGKTFMFPIALLSVSGMMLGLGAGFTDPKM
                     IEMVPFLGNEYVNLVLNFMLTIGLFAFNNLGALFAMAIPLGLLKKEKEFGAFSGLVGF
                     IAMHIGTNFYLTRADLLVPAEQMSTNGQAMIMGIQTYNTSVLGGIVAGLIVYAIYDKV
                     SNLKIPESLGFYSGPRLVPIVSLIVMSIVGLLIPIVWPPFFNAFQSLGRWISSAGPLG
                     YFSYAVAERVTIPFGLNHLVTSVFRFTPIGGTAVIDGETYFGTLNMFMAYVENNQIIP
                     LDLAGKMEQGKLMIQYGLAGAALAIYRTAKPENRKALKGLLISGVLTVIIGGISEPIE
                     FLFLFISPALFAFHTFMNGLANMVLPYLGVLMGFTGDLIAFISFGVLRGTATGWPIAV
                     LVAVLYFAIYYFVFKWAIIKFNIKTPGREDKEIKVSEGNGSDFKNLSTYKGQQMISAL
                     GGQSNILSLDNCVTRLRLKLQDVSLINEDAIKEAGGIAVVKLDEHTIQVIIGTQVYSL
                     RKQMDKAMEGHLEACND"
     gene            3094..4278
                     /locus_tag="JAM15_08870"
     CDS             3094..4278
                     /locus_tag="JAM15_08870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAT6798359.1"
                     /translation="MINFDKKVDRLGTYCTQWDYVEDRFGKKDLLPFTISDMDLEFPF
                     EITEVLQERLNHRVLGYSRWKHDDFRNSVTNWYIKRFNCSVDSNWIYYSPSVMYSISK
                     LIEMLSNEGDGILINTPAYNAFYDVITNNNRNIIKSHLVNRNGFYSIDFNDFEKKCKK
                     SKIFILCNPHNPTGRVWSELELVKMIGICKNNDVKIISDDIHMDIVYDNRMTPILNVA
                     KDYLDSVFICTSASKSFNIPALTGSYVIIPNEGIRNKFENITRYRDFVNSPAILAILA
                     TMVCYDDCEYWLDELLKYLKENLKYTIDYIKDNLEPLKLVMPEGCYFAWIDFSELKIS
                     GDKFQKLLMDIGEVAIMSGSVYGEEGEFYLRLNVACSREKLEDGLNRIKKTMDYIAKR
                     TL"
     gene            4296..4895
                     /locus_tag="JAM15_08875"
     CDS             4296..4895
                     /locus_tag="JAM15_08875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAT6798360.1"
                     /translation="MGYLKTMVDVMTTEMNAIRCLIDEAGIEYESIVSEIANCEGKVI
                     FMGVGKSAHIGKKLAATFASTGTPSFFVHATEAVHGDLGMIESKDITILISNSGNSME
                     VVNCIKYIKAIGSKIIAFTSNRNSVLAKECDYALIYPAKDEADHLNLAPTTSSTITLV
                     LGDSIACALSKSSNFGSSDFYKYHPGGSLGEKLKTANNG"
     gene            4919..5389
                     /locus_tag="JAM15_08880"
     CDS             4919..5389
                     /locus_tag="JAM15_08880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAT6798361.1"
                     /translation="MFKMFKKKSIKSPISGKVIELSKIQDGVFSQKIMGEGVAIDSTG
                     DIVYAPINGKIVVVAETKHAFVIELENGMELLIHVGLDTVNLKGEGFEALVSMGEQVK
                     EGTPMLKINRPLIESKGISLITPVTITNHSEYNMNTCNVGNSVEGGKDTVIEFK"
     gene            5747..6493
                     /locus_tag="JAM15_08885"
     CDS             5747..6493
                     /locus_tag="JAM15_08885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HAT6798362.1"
                     /translation="MKIENLSIDDIKRGYIFNDDLNCYSCIKCTKTYEVGEIYKIGNR
                     FFEASKAIELHMELEHSDYLEQLLNSDSKYNTLTENQKQLFQLFISDLPDKEIAKQVG
                     VSTSTIRHQKFIFREKAKQAKLYLALYESVFEDKSNKSSTIIPIHEHARMVDERYVVT
                     EEEKKHILDTSFESMNPLKLKVFSSKEKKKVVILSKILEQFERGKKYSEKEVNQILES
                     IYDDFATIRRYLIEYSFMSRNKECTKYWLT"
     gene            6555..7229
                     /locus_tag="JAM15_08890"
     CDS             6555..7229
                     /locus_tag="JAM15_08890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase"
                     /protein_id="HAT6798363.1"
                     /translation="MNDELKSILYNKGVDIVRFVDISEFPINQTQGFSKAILFCIGLS
                     KKFITDIYNNLPTDSDEFLEKEEKVEELADWISKYIQNKGYRAYSQSEKNNLEHGYFE
                     KAYINPEMQSGISPLPHKTIANISGIGFMGKNNLFVTEEYGCAFSMCTVLTDAPISVE
                     RYPLIDSKCLNCNVCVENCPAKAIHGNEWTLPGKRESIIDVSKCFCALRCMMSCPWSL
                     RYANQK"
     gene            7597..8943
                     /locus_tag="JAM15_08895"
     CDS             7597..8943
                     /locus_tag="JAM15_08895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798364.1"
                     /translation="MEIETKTPDWINVLELNSKIDITGKYDVSNMIQDIVSDKSLEGS
                     IIYFPKGNYLFEKGIKISQQITLQGDSYYGGDNQVSNLDNKQSIVGTTNFITRGVSNI
                     SIITLEGTSQCIKNINFYYDSHDIEKIPPKNVSAITEYGETQGLFHFEHLFISGFSGI
                     GIEIPYYSTGNDIIVSSCGLGMRLGEKSMLSSSKIYECKNGMEITTGVSLNNVRIEEI
                     REIGINNKGFGFNLIMNLMVDQCGYCGFMFEKMCYSQITARITKCGQYYKSVDYNTYE
                     NMEDRKEEAYSIFYGDILENCNIVLMNSNIDTLENDSLDEHKIYVIKANETNKVMLTC
                     YAEADELIQCAKGNLLLENGENTYKFYNGEICSVGGVQISDIDEKDLIKIIENTLYID
                     DKGKYLMVPRLKKNTVIYSVLDSIEEINKLHGGIWEQIDVKVLAGESMYYYKKIKD"
     gene            8970..10370
                     /locus_tag="JAM15_08900"
     CDS             8970..10370
                     /locus_tag="JAM15_08900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798365.1"
                     /translation="MEESIIIKDISGWINVLDYGICNDETKDVSSKLQEIIDAAPEDS
                     IIYFPKGKYLFESGVKIKKRLTLCGDSYILANVPKNTAGVTQFTFKGKKNPKSENIAI
                     ITAKSVRHCIKSICFYSDSCDRDMTSNHEPPTDGKPRFHHNVIINYRNISAIVCEDKQ
                     GEPGHYENLSFSGFSGSALDMPNNSTANDITVFTSGLGISTGENSTIANSKVWGCVDG
                     MIISTGTFINGMRVEEIKKVGIKNIGRGLNFITNITIDQCGYCGVWFDSISNVQISGN
                     ITRCGQYYYDVSYDNYLMLDNRVKEAYSLFYGNLLESSNIVLSNTNKDNWEDFKEDKH
                     KVYLVEALETKNVLLTCNIDATDWIVKSEKGNLTYNNMRQTVIFYDGKLSSINGIGIS
                     DEDYGDKVKIKKGNIYINSKDKVIKMHKPEVGDIMSTIIKDENILSAHYGGTWGKIGE
                     KIEFGITVHYYKLIEK"
     gene            10580..12016
                     /locus_tag="JAM15_08905"
     CDS             10580..12016
                     /locus_tag="JAM15_08905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798366.1"
                     /translation="MEGRTGIKDGRWINVVERGIKNDGSYNIGPDLQDIIDEIETDFC
                     VLYFPKGKYLFTSGVKINKEIVLQGDSNSPTETTQFITRGVENMSIITLTGKKQCIKN
                     INFYSDSCEIQVNEEPPTKGNPKYHYEMIINKNEKNVEMNNVSAILYDNSKNMIKGLG
                     HYENIYISGFSGTGIRIPYYSIVNDITVSSCGLGIDTGIDTIISNSRISKCQNGMRIR
                     TGTSINNVRIEKIQKVGLISSQVKDYEGYGSYKINNITIDQCGYCGFLFDSVKGSYFS
                     GIIRRCGQYYYNTDYDTYLSIKDRVEEAYSLFYGNYFTECNIDLVSDNKDNWDDGLEY
                     KHKVYVFKTLQIPKLTLRCNIDAYDYIVKSVHGGGNLMLKNNFNNYIFIDSSSPEVIN
                     GINFNYQKNGNLLRLNNGKLSYKNGKEETAIFRPNYGLIVASTDSECEQIETSYGGKW
                     EKLGSEVIGKETVYYYKHHEPDKTNQIK"
     gene            12360..13304
                     /locus_tag="JAM15_08910"
     CDS             12360..13304
                     /locus_tag="JAM15_08910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1848 domain-containing protein"
                     /protein_id="HAT6798367.1"
                     /translation="MIVSVSRRTDIPAFYSKWFFNRLKEGFVYVINPMNPKQVSKIEL
                     NPHTVDCFVFWTKDVTPMLYDLNKLKDYKYYFHYTITSYGKEVETCILDKRKVIDSFK
                     ELSRKIGKERVILRYDPIFLSEKYTIDYHIKAFASLCNQLDGFTEKCIISFIDLYKKT
                     KFNTKALHIKPIEITEIETLSKEISKIAHKHGIILEMCSEEYNLSKFGIGKSKCIDDR
                     LISKIIGCEVEVKKDSTQRDICGCVKSVDIGQYNTCRHYCLYCYANFNYAKVEENCRL
                     YKEDNKLLIDTLRDDAKISIRDMKTIKVDKNKQISIFD"
     gene            13473..14405
                     /locus_tag="JAM15_08915"
     CDS             13473..14405
                     /locus_tag="JAM15_08915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HAT6798368.1"
                     /translation="MNLLKKYPIPIASLILSIFTLGNLLQSYSESLRNVIGFIGFILY
                     AIYIVKIILLRKGVKEQLENPLISSTFPTITMATMIFATYIKPLSLELSIMIWSIGIV
                     GHLVLIVLFSKKFLVKFSIKTVFPSWYIVYVGIVAASVTAPAFNQLLIGKIAFWIGFV
                     SYIVLIPVVLKRVWIIKEMPEPSLPSIAILAAPGSLLLSGYINSFSDKNNVVLYLLFI
                     LSIVFYIIVLGYLPKLLRLPFYPSFAAFTFPMAISAMGMKLMNGYLTKSGHFISWISY
                     ASKLEEIIATVIILYVLVLFIIYLSKSETTSKAK"
     gene            14510..14977
                     /locus_tag="JAM15_08920"
     CDS             14510..14977
                     /locus_tag="JAM15_08920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C_GCAxxG_C_C family protein"
                     /protein_id="HAT6798369.1"
                     /translation="MKTKEEYLKEVRNISEEYFRKGEFFCSEAVLQTINDALGQPLSP
                     EITKLASGFPIGLGKAQCLCGAISGGEMALGIVYGRVHGETMNPKMFEHAKGLHDYIK
                     KEYGATCCRAITKKWDGDNFMSPERKEHCIKITGQVTEWVADKLIEDEKLNIK"
     gene            complement(15221..16075)
                     /locus_tag="JAM15_08925"
     CDS             complement(15221..16075)
                     /locus_tag="JAM15_08925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HAT6798370.1"
                     /translation="MLTIIIALLPVMGWGLMPIVANLKKSSPHEQLLGTSISAFIFST
                     IITLVIHPEITFFSFCISMISGIFWSLGQLMQFKAIQIASVSKVMPISNGSQLTFTTL
                     LAVILFNEWTSSKMLLIGSLSILCIILGILLTNYQTKKSTDKNMLKCVGVVLLSSLFL
                     SLYVVTNQIFLIEGYRIILPQSVGMLITSSIIVKYFSKEIVYRENVLFNLITGILWSI
                     ANLGMFITTNTLGVTISFSISQSCVIVATLGGIIFFKEKKNKKEWLAIFIGIILIMSG
                     VFMLSIIK"
     gene            16241..18205
                     /locus_tag="JAM15_08930"
     CDS             16241..18205
                     /locus_tag="JAM15_08930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HAT6798371.1"
                     /translation="MLTDMIQNREIKIIKFLLKEGHTTVKAIADDLDVSEKTVSKSLK
                     EVEAVLKKIGLSLIRKPKIGVYIDGDLKKILPYLDNKGSQIPTTREERVIYIYSVLLK
                     SNDYITIQQLSDELYISRGTIERDLAEVEKLLKNEGISIYKKPSKGIKLNISERDKRQ
                     LTAKFIHKFWSRNWYIKQEQESFYQAFEKIQADVNGIFSEDDLSIIIDILRNFSRERK
                     FEFSDYEFQSLVIHLAIAVERIRKGEYIEESLYIGNIENNQMSNTNYLAKQLEEKFSI
                     LLPKSEIGYINLHLVAADQHRDTNELKNTSTNPCETSTNNISNLREIIKNTLYETAYD
                     KDLIDGLTSHVHSSINRLKYGLSIKNPYVNTIKQNFSLSFEQALDLKKVIEFIYDIRI
                     NDDECAYIALHFEAFRERMKELPQNIRVILVCSTGLGSSRLLSARIKKYFPMIKIEKV
                     LSVQELVSSKIDADLVISTIYLELETIPTIVVSPILNESDIRTLERNIQNVSCCTSKK
                     YKSFRNLIFEENILLNIEASNYEDAIKYITDNLIKKGFVKEGIAKSAIERENLSYTSF
                     QSIATPHANPSYIKKSNISVATLKNPITWGNEKVEVIFFISLENDKNLELDEIYEVFY
                     DFIDNKKNINDILSATSTKEVYDLLLEESI"
     gene            18205..18666
                     /locus_tag="JAM15_08935"
     CDS             18205..18666
                     /locus_tag="JAM15_08935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAT6798372.1"
                     /translation="MKISDVLKKEQIVFNLDTNTKEETIKKLSSIFVENGIVDNEEEY
                     VKSVLEREEHSTTGIGNGIAIPHGKSDAVKKSSIIFAKTKHKIEWDALDEKPVDSIFL
                     LAISNIDKDSNHLVLLSKLATKLMDDDNVDALKLANSEQEIINIFSEEGEM"
     gene            18669..18989
                     /locus_tag="JAM15_08940"
     CDS             18669..18989
                     /locus_tag="JAM15_08940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HAT6798373.1"
                     /translation="MKRKIIAVTACATGVAHTYMAAQALKKASKKMGHLIKVETQGAT
                     GIDNELTTKDAQIAEVVIFAVDTKVRNAERFEGKEILEVPVNAPIKDAEKVINDALKL
                     IDTK"
     gene            19005..20105
                     /locus_tag="JAM15_08945"
     CDS             19005..20105
                     /locus_tag="JAM15_08945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HAT6798374.1"
                     /translation="MLKKIVSELKKHVLTGISYMIPLVIAGAMIMAISRVGGSFYNIP
                     DIWDAKYAESASSIVRLLHDLDGFGGTALGLMFPVIAAFIGFSIADKLAIVPGLVGGM
                     IAKDIGAGFLGALAVGLIAGYTCLFIKNHVKLPKSAASIVPIFIVPVFGTLITVVLIN
                     YVIGIPFATLNTGLENWLNGLSGTNQILMAAIIGAMMAVDLGGPVNKAALTTSLALLT
                     SGIYAPNTAAMVGIVIPPLGLGLATILAKQKYNKQLREAGKSSLIMGLIGVSEGAIPF
                     AVESPLKVIPSCVIGTAIASAMAVGLGSVNATPISGFYGWFTVENWPMYVLSIAVGTV
                     IVAGLVIVLRGNPVIEDDEFEDDDFDEAEWES"
     gene            20225..22825
                     /locus_tag="JAM15_08950"
     CDS             20225..22825
                     /locus_tag="JAM15_08950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HAT6798375.1"
                     /translation="MIKAHIVNHTHWDREWYFTSGDALVLSEQLFTDVIDELERNPDV
                     SFVLDGQLSILDDYVQLHKEKIEIIKKLIKEDRLHIGPWFTQTDAFFARGESILRNLM
                     IGIFESKKYGKYMKIGYLPDTFGFNAQMPILLKHVGLDNIFFWRGIHLGKHVQSPYFK
                     WKSLNGESYIYAVNMPHGYGTGMLLEPSLKYVNGRLDPAVDFIKSYTDVDEVLIPSGN
                     DQLNIIGDFKNKIKAINDIGKYSYITSSYQEFLKYIKSIESLESYRGEFREPVLARIH
                     KSIGSSRMDIKLACDKLENKLIKRIEPLLVIAKKSKIEISNQLLINTWKKLLEGQAHD
                     SLAGCVTDTVTDYILHRIREANEICDSIENTIVKKISEGLKLSKNDILVFNTEAKRFN
                     GYKEIQVVSDSKNIYFKYNLDATIIEETYVKPRENVLEETPAGNVFIEEPGYYILKVR
                     INVQLPALGYKVVSFESSDKEMVSLDKSNDTFISNDNYKIIYEDGSLNLQLKDGTYIS
                     NFLILKDSGNAGDTYDFSPLKNDEDIKLSFDRVYTEKALGYEKLVVKGTTLLPLTLED
                     RKNKYLNGKLNVKVSIVLSKENPLMDVKLCVDNTIYNHRLRVHIKTDIKDNKNIASLP
                     FGYITRENGVLDNWEDIYSEMPIDLEPLESNITLTNQNRSCTVFTRGIKEYQHIEDEI
                     ALTLLATTDELGKPDLLYRPGRASGDTTKKGHIRIKTDKAQMLKKLEFSFAIYMDSKS
                     FDELEIANLTHNYLRECVNYQLQDYNFFLYRIDNKIQKSIVNKTISRELEIISLPEKY
                     LISACYPSYYSKDKFIIRVENPSSNRMILDEQIFKNRNGKIVNAIEDVEEEQVYEIAP
                     FDVISILLDL"
     gene            23294..23629
                     /locus_tag="JAM15_08955"
     CDS             23294..23629
                     /locus_tag="JAM15_08955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6798376.1"
                     /translation="MYNIDDMIYNCPVEALSNILGKKWVAIIIWKIQEDKKRFGELQR
                     AIPDCSKKMLVQQLDFLIEQGIIVNQKKLVNNVVESTYFLSESGLRLLPVMEKMIMWS
                     NKNLNCDKY"
     gene            23766..25043
                     /locus_tag="JAM15_08960"
     CDS             23766..25043
                     /locus_tag="JAM15_08960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HAT6798377.1"
                     /translation="MQNVNLFLVFIEGIVSFFSPCILPILPIYLSILSNSSVENLKEG
                     KTSFIGSSLFKNTIFFALGISTTFFILGSSVKALSMFFNENKDLIMFIGGIIIIIMGL
                     FYMGIIKSSILNREKRFNVKFKEMKAITAFILGFTFSFGWTPCIGPILASVLVMVSSS
                     SNHLSANLLIAVYTIGFILPFIITAMFYSKLFKTIDKIKSNMEIIKKIGGIILIVSGI
                     LMMVNGFGSISKHFNTSQNSKIESKQEENKRENSTDKEENSDGNNSQKDSNNDNNDNG
                     SNDEDRIKSIDFTLTDQYGKTHKLSDYEGKVVFLNFWATWCPPCKEEMPYIEQLYKDY
                     NKNNDDVVILGVASPNLGREGSREHVVNFLKDQGYTFPVVLDEDGALAYQYGINAFPT
                     TFIIDKEGYVTQYIPGAMDKATMASFIENQRNK"
     gene            25164..26552
                     /locus_tag="JAM15_08965"
     CDS             25164..26552
                     /locus_tag="JAM15_08965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAT6798378.1"
                     /translation="MKKTFDAIIIGFGKGGKTLAGDLANRGLKVALIEKSNKMYGGTC
                     VNVACIPTKSLENSANSVKTKNINSWDEVQAEYEKAIDKKETLITKLREANYNKLNSN
                     ENVTIFTGMGTFIDEKTVQVKTENEIYELVADNIFINTGSRPFIPNIKGIENKNIVYD
                     SESLMNLRVLPKKMTIIGAGFIGLEFAGIYSSFGAEVTILNSNNGILPNEDVEDSEEI
                     IKLLAKRNVKIVNNANIKEIKEVSESAIVEYEVDGKSKELTSNMILVATGRKANTEGL
                     GLENAGIELNERGFIKVSETLKTNKEHIWAIGDINGGPQFTYISLDDYRIVINQLFGD
                     KTRTTNDRKNIPNSIFISPAFSRVGLNVKQAKEKGYEVLVAKMPVEAIPRAKQIGKAD
                     GFIKIVINKKSNKILGASMICENSSEIIHLIQLAVDLEVEYTYLRDRVYAHPTMTEAL
                     NDILSPNMIKEV"
     gene            26932..27636
                     /locus_tag="JAM15_08970"
     CDS             26932..27636
                     /locus_tag="JAM15_08970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009607700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF434 domain-containing protein"
                     /protein_id="HAT6798379.1"
                     /translation="MSKRGFDDSDKRWFSSKELTRLIKAKEEIEWLLNRDYKIDPVVT
                     FVGDRYQFSIRQRDALKRAVCTDEKNIIRQSKRLSLDKIKEDTVNIDGFNLIISIEVA
                     LSGGTLVIGSDGNIRDLAGLRGTYKIIDKTEEALNLIGKIFNKYNAQNLKFYLDAPVS
                     NSGNLKYRILEHAKTWGIETEVELVKNADVVLEKLDRVVSSDAVIVDKCISYFNVARG
                     IIEEYIKECNIINLNK"
     gene            27772..28623
                     /locus_tag="JAM15_08975"
     CDS             27772..28623
                     /locus_tag="JAM15_08975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HAT6798380.1"
                     /translation="MKLTKLNIKKYRAPIYKYALANVNLRSAKSTNSSIITVIPQGAK
                     MEVLDEEDDWIKVMYNSQEGYVYKDLVSVSEYAWSNLNLREDKSITSNIITVIPEKSR
                     VEVLQVDGDWSKIVYDDKIGYVFNYFLSIDGNKPNELDYKYFYTDMIKFVNENNIKST
                     SDYLIVTDLRNKYTYIFKKDNGGWGQLYKWQCTIGKPETPTITGIFYISGRKPSFGTD
                     EYSVKYATRIKGGYYYHSVLYDSTGSYIIDGRLGEALSHGCIRLSTENAKWIYDNIPD
                     TTTVIIH"
     gene            complement(28778..29923)
                     /locus_tag="JAM15_08980"
     CDS             complement(28778..29923)
                     /locus_tag="JAM15_08980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HAT6798381.1"
                     /translation="MSTYYVPPINLLGKGCLNEAKDSIKSLGTKKAFVVSDKFLVSNG
                     TVKKVTDILSQIDVDFVVYDEVKQNPTVTNVDKGLKILKSENCDFVITIGGGSPQDCG
                     KAISILATNGGDIRDYEGINKTSKKCLPIVAITTTAGTSAEVTINYVITDEDRHVKMI
                     MVDTNSLATMTVNDPELMISKPSNLTAATGMDALTHAVEAVVANGAYDVTDSTALYAI
                     KQIFKYLPRAVKNGNDIEAREQMCYACFLNGIAFSNAGLGNVHAMAHQLGGLYDLPHG
                     VCNAMLLPIVEEENAKSAPAKFRPIAEVIGMDVNNKSDKECVDFVIDKIKALSEEVGI
                     PKSLKDVGVDNPNFELLAENSMKDACAGANPVFFDKEKIIELFMKIS"
     gene            complement(30256..31032)
                     /locus_tag="JAM15_08985"
     CDS             complement(30256..31032)
                     /locus_tag="JAM15_08985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HAT6798382.1"
                     /translation="MTSDNHRPTARILDILEALAESENGYTLTEIADVINAPKSSIFP
                     IVHTLNARKYITIDKNTSKYSIGIRSYTLGSSFFEKRTIFNYIIDEMTNIVNSCSETC
                     QLGILDNNEVLYIGKVDSPEPIRLISYVGKKIPANCTGLGKALLCDFDKEKLISLYPD
                     GLKGFTEKSITDFDVLYDQLLEVQRTQIASECEESMEHLKCLAVPIRKNGCIRAAVSV
                     TLPLFRANDEKIELIKKLLLNAQKNIQSMMEERNEDIVIN"
     gene            31614..32588
                     /locus_tag="JAM15_08990"
     CDS             31614..32588
                     /locus_tag="JAM15_08990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HAT6798383.1"
                     /translation="MIMDFIKKIPAGMMIVPMFIAAFINTFCPDIVQIGSFTTAVFSS
                     VGSATIIGVQLVCLGTQLQFREMPKVLKRGGILLGSKFAIGALIGILIGKLFGMDGVL
                     GLTTLAVISAVTNSNGSIYLSLMTSYGDETDCATMSLLTLNDGPFFTLIALGTSGLAN
                     VPLLSLLAAIVPILVGMIIGNFDKKMKEFLEPGCNLLVPFVGFALGSSINLASILKGG
                     LSGVLLGLISVFVGGIFIVFCDKFIGKRPGYAGWAVATTAGNAIAVPAAVALVDPSWQ
                     PYVATATTQVAAAVVVTAILVPLITSWWAKKYGCPKFPKQNEDGTITA"
     gene            32686..32991
                     /locus_tag="JAM15_08995"
     CDS             32686..32991
                     /locus_tag="JAM15_08995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HAT6798384.1"
                     /translation="MINAVIIDEKDNVAVAIEAIAKGNEISFKLKDKTVKTITALDNI
                     TIYHKLAIKDMAQGDKVTKYGEHIGEANQEIKSGQHVHIHNVRSVREDLDKQVMTNI"
     gene            33147..34307
                     /locus_tag="JAM15_09000"
     CDS             33147..34307
                     /locus_tag="JAM15_09000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005979864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HAT6798385.1"
                     /translation="MKFYGYKRPDGRVGIRNHILILPTSVCASDTTRIIASQVQGAVT
                     FNNQNGCSQVHSDQQLTMDVMAGYAANPNVYGVIVVSLGCENCQNDLVVDAIKERTNK
                     PIKTLVIQEEHGTLKTIEKAVRYAREMAQEASLLRKEEFPISELILGTECGGSDPTSG
                     LAANPLIGELSDKLVDLGATSILSETTEFIGAEHILARRAVNEEVKEKILHIVHRYEN
                     SLKLVGEEVREGNPSPGNIAGGLTSLEEKSLGCIHKGGHRQISEVYDYAKQIDKKGLV
                     IMDTPGNDASSVAGMVAGGAQIVVFSTGRGTPSGNPIAPVIKITGNKITFANMEDNMD
                     FDASPVIYGPQTMEELTDDLLNMVVDVANGKQSKAESLGYTEMAIARVCNYV"
     gene            34357..35259
                     /locus_tag="JAM15_09005"
     CDS             34357..35259
                     /locus_tag="JAM15_09005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HAT6798386.1"
                     /translation="MKFVSFTEGENECKRTGVFSKDELFIIDVNSLNLSRNFKDLNEL
                     IQNVSSEDIIKLKTIINGSIFYNYDVFKRERCTVHVPIEKPIHDILCVGVNYKDHLEE
                     TQTHFDDSFEEPQKTVYFTKRVTKAIGPEDEIDGHFEINNQLDYEVELGVVIGKTGVN
                     IRKEEVEDYIFGYTVINDISARKLQKEHVQWFRGKGLDTFTSLGPCILHKSAVPFPIK
                     LKVCSRVNGEERQSSNTGLFISDVSDIVSELSKGMTLEAGDIIATGTPSGVGMGFSPP
                     RYMSSGDVVECEIESIGILKNYIK"
     gene            35339..36232
                     /locus_tag="JAM15_09010"
     CDS             35339..36232
                     /locus_tag="JAM15_09010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HAT6798387.1"
                     /translation="MKAEFLTPVVTIFDEEGNLDKEGNKKVYDHLIDGGVDGLVIMGS
                     TGEFFNMSMDMQKELIDLVTSHVNKRVKVFIGTSRMCINESIELSNYAHNSGADGVMI
                     ISPYYFSLDDDSIELFYSEIAKNTEAEIYLYNYPDRTGYDLSPELTLRLARKHKNIVG
                     YKDTVTLMGHTRDLINTMKIEFPEFKVYSGYDENFIHNLMSGGAGCIGGLSNLIPEVC
                     SKWAEAYNNRDMEKVIEIQKYINKAMDFYLITNPFIPAMKKAMNIRGLQISDYMTAPF
                     VKPNEKQVCEIKKLMNKLNIC"
     regulatory      36285..36466
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            36694..37824
                     /locus_tag="JAM15_09015"
     CDS             36694..37824
                     /locus_tag="JAM15_09015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAT6798388.1"
                     /translation="MKFKSNVLKQFFLIAMVIFMVGGLIGCSKSDKENKQASTGKKLE
                     LKYASGFSVEDLEDGIKKVTDGDNRELILIPKKIKIPEKYKNANIVRTPVDNVLIAST
                     TQACSLRTIDELDSIKAVTTEEQYWTIKEIKDLMKDGKIHYVGSNLAPDYEKIVDLNP
                     DLTIVSSGLSEADTKFIDKLKELGLNYVVDNEYKEQNPFGRMEWTSLIAAFYDKEDMA
                     TSELNKTVQKVEEVSKKIKNKAKPKVVWASVYEGSAYIAPKDSYVDNMIKMAGGINAC
                     ASIDSNEGRVSIEQLHEVAKDADIFVYSSSSDYAPNLDSIKSSAPVLADLDVVKNGNL
                     WVFAPDYYQSVDKTDELIVDLVEMFHPGTTGEKIKHYINYDK"
     gene            37896..38741
                     /locus_tag="JAM15_09020"
     CDS             37896..38741
                     /locus_tag="JAM15_09020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HAT6798389.1"
                     /translation="MDFINKMRIRNTTIFIVLIISMILTFLVCVAFGSVKIEFKEVID
                     VVLRGMDNTEHYKIIYNIRIPRVLATMVGGACLAVSGILLQIFFKNPIVEPYILGVSS
                     GSTLSVALMILGGYTLGFESVNSMSIFVAAFIGALIVMSIVILFANKVKNITTLLIIG
                     IMTGYVCSGITNVLQSFANSDKLKEFTMWSMGSFSGFTWEKVEILIIVGMLGLLMTVF
                     IIKPLNAFLLGEEYAKSIGVNISFFRVLIVFISSILAAIVSAFAGPIGFIGLAVPQIS
                     KLIKK"
BASE COUNT        15136 a         4109 c         6835 g        12723 t
ORIGIN      
        1 agtacaaagc tataatctga atttcaataa atatatatat aattaagtta aaatacttga
       61 aaatactgga aaaaactgaa aataattttt gtaatataaa atgtcgattg attttaaata
      121 attaaatata cataagaaat aattaaatat atttcaatga aaatatgata aaatatgaca
      181 aattaattga tgacaataaa aaatattttg ttattgtagt attatagggt aaattgcaaa
      241 atatatacga aagtaaaatt ttaaatattg acattaaatt aaatatacta tactatgtaa
      301 gtgtgatgag agaatttttt tagaggggat ttatagtgaa tataaaaaag atatttaata
      361 acaatgtagt agtaagctcc ctagaagatg gcacagaaat aattgtcact ggtgctggag
      421 taggatttaa gaaaaaagta ggcgatttga tagatgaaaa tttgatttct aagaaatatt
      481 ttgttcaaga cgatcaaagg gacaaataca atcaaatact taataagacc tctattgaat
      541 actttaaaat ttcagaagaa attatagaaa aggctaatga agttttaaat actcaagtga
      601 atgattcaat aatattagcc ttaactagtc acatagaatt tgctgtccaa agagaaaaac
      661 aaggtataaa attaccaaac ttaatattga atgagacaaa acaactttat agggaagaat
      721 ttaaatttgg attatgggca attgatgaaa ttgaaaaaag gataggaata aaattgcctg
      781 aagatgaagc aggatatatt gctattcaca taatcaatgg tttggaaaat tctcaaaaag
      841 atgaaggtat taatatacta gagttttcaa aacaagttat tcagataatt gaagaagtac
      901 atggatttaa attggatgta aattcattaa attatactag acttataact cacttaaagt
      961 tttttgttca aaggattctc cgaaaagaaa cttacaatga tagtgatatt gaagatatgt
     1021 ataagttagt gaataaaaat tacaataaac ctaaagtgtg tactgaagaa attgcagcat
     1081 tggtattaga cagatttgaa tataagatta gtaaagaaga agaattatat ttaatgattc
     1141 acataaataa aataacaaac agtggttgtt aggattgtaa ctgataaagc aggcaaaacc
     1201 taagtcattg agcttaacta ttagattaag ttttttgatt taggtttttt tattagatac
     1261 aatcaaaata cagacagtga cttttaggat tgtaactggt taagcaggca aaacctaaat
     1321 cattgaattt aactattagg ttaagttttt tgatttaggt ttttttatta gatacaatca
     1381 aatacagaca gtgactttta ggattgtaac tggttgagca ggcaaaacct aaatcattaa
     1441 acttaattat taaattaagt tttttgattt aggtttttct ataaatttga ttatgttttt
     1501 agataaaaat aggaggggaa attatgaaaa aaaataagtt aggtttatgg aacttcttcc
     1561 aaatgttagg aaaaacgttt atgttcccaa tagcactact tagtgtttct gggatgatgc
     1621 taggacttgg ggcaggtttt acagacccta agatgattga aatggttcca tttctaggga
     1681 atgaatatgt taacttagtt ttaaacttca tgttaacaat aggattattt gcatttaaca
     1741 acttgggagc attatttgca atggcaattc cactaggatt attaaaaaaa gaaaaagagt
     1801 ttggtgcttt ttcaggatta gtaggattta tagcaatgca tataggtaca aatttttatt
     1861 taacaagagc tgatttgtta gtaccagcag aacagatgtc aactaatggt caagctatga
     1921 ttatgggtat acaaacatat aatacaagtg ttttaggtgg tattgtagca ggattaattg
     1981 tttatgcaat atatgataaa gttagtaatt taaagatacc agaatcatta ggattctaca
     2041 gtggaccaag attagttcca attgttagtt taatagttat gagtatagtt ggattattaa
     2101 tacctattgt ttggccacca tttttcaatg cattccaaag tttaggaaga tggatttctt
     2161 cagcaggacc attaggatat ttttcatatg cagtggcaga aagagttaca attccatttg
     2221 gactaaatca tcttgtaaca tctgtattcc gttttacacc aataggtgga actgctgtta
     2281 ttgatggaga aacgtacttt ggtacattga acatgtttat ggcatatgta gaaaataatc
     2341 agattatacc tcttgattta gctggtaaaa tggaacaagg taaattgatg attcaatatg
     2401 gattagctgg tgctgcattg gctatctacc gtacagcaaa accagaaaat agaaaggcac
     2461 ttaaaggact tttaatatca ggagtgttga cagttattat aggtggtata agtgaaccaa
     2521 tagagtttct attcttattc atatcaccag cattatttgc tttccataca tttatgaatg
     2581 gtctagcaaa catggtactt ccatacttag gcgtgttgat gggattcaca ggagatttaa
     2641 ttgcatttat aagttttggt gtgttaagag gaacagctac aggatggcca atagcagtat
     2701 tagtagcagt tttatatttt gcaatatact attttgtatt taagtgggca attattaagt
     2761 ttaatataaa gaccccagga cgtgaggata aagaaataaa agtatctgaa ggaaatggtt
     2821 cagatttcaa aaatttgtct acatataaag gacaacaaat gatatctgct ttaggtggtc
     2881 aatctaatat attatcacta gataattgtg taactagatt acgtttaaaa ctacaagatg
     2941 tatcattaat aaatgaggat gcaattaaag aggctggtgg tatagcagtt gttaaattgg
     3001 atgagcatac aatacaagta attataggaa ctcaagtgta ttctttaaga aagcagatgg
     3061 ataaagctat ggaaggtcat ttggaggcat gtaatgatta attttgataa aaaagtagac
     3121 cgattgggta catattgtac ccagtgggac tatgtagaag atagatttgg taagaaggat
     3181 ttgcttcctt ttacaatttc agatatggat ttagagtttc catttgaaat aacagaggtg
     3241 ttgcaggaaa ggttaaatca tagagttttg ggatacagta gatggaaaca tgatgatttt
     3301 agaaattcag ttacgaattg gtatattaaa agatttaatt gtagcgttga tagtaactgg
     3361 atatattata gtccaagtgt aatgtattca attagcaaac ttattgagat gttaagtaat
     3421 gaaggagatg gaatccttat aaatactcct gcatacaatg ctttttatga tgtgataaca
     3481 aataacaatc gtaatattat aaagtcacat cttgtaaata ggaatggatt ctattcaatt
     3541 gattttaatg attttgagaa aaagtgtaaa aaatctaaga tatttatttt atgtaatcct
     3601 cacaatccaa ctggtagagt atggagtgag ttagaacttg ttaagatgat aggaatttgt
     3661 aagaataatg atgtcaagat aatatcagat gatatacaca tggatattgt atatgacaat
     3721 agaatgacac ctatcttaaa tgttgcaaag gactatttag attctgtatt catttgtaca
     3781 tcagcgtcta aatctttcaa tataccagca ttgactgggt catatgtgat tataccaaat
     3841 gaaggtatta gaaataaatt tgaaaatatc actagatacc gtgattttgt aaattcgcca
     3901 gcaattctag caatattagc tacaatggtc tgttatgatg actgcgaata ttggttagat
     3961 gaactattaa aataccttaa agagaatctt aaatatacga ttgattatat aaaagataat
     4021 ttagaaccat tgaaattggt catgccagaa ggctgttact ttgcttggat agatttttcc
     4081 gaacttaaaa taagtggtga taaattccaa aaattattga tggatattgg agaagttgct
     4141 attatgtcgg ggtctgtata tggtgaagaa ggtgagtttt atttaaggtt aaatgtggca
     4201 tgttcaagag aaaaacttga agatggttta aataggatta aaaaaactat ggattatatt
     4261 gcaaaaagaa ctttatagta ggaagggaga tagttatggg atatttaaaa acaatggttg
     4321 atgttatgac tactgaaatg aatgccataa gatgtttaat agatgaagca ggaatagaat
     4381 atgaaagtat agttagtgaa attgcaaatt gtgaaggcaa agtaattttt atgggtgtag
     4441 gaaaatctgc acatataggt aagaaattgg cagctacatt tgctagtact ggtacaccta
     4501 gcttttttgt acatgcaaca gaggcagtgc atggagattt aggaatgatt gaaagtaagg
     4561 atattacaat tttaatatca aatagtggaa attctatgga agtggtaaac tgtataaaat
     4621 atattaaagc aataggttct aagataattg catttacttc aaacagaaat tcagtactgg
     4681 caaaagagtg tgattatgct ttaatatatc ctgcaaagga tgaagcagac catttaaatc
     4741 tagcaccaac aacatcatct acaattactt tggttttagg agattctatt gcatgtgcat
     4801 tatctaagag tagtaatttt ggttcttcag atttttataa gtaccatcca ggaggaagtt
     4861 taggtgagaa gttaaaaaca gctaacaatg gataaaagca aaaaggagag tagtttttat
     4921 gttcaaaatg tttaaaaaaa aatcaataaa atcacccata tcaggaaaag taatagagtt
     4981 atctaaaata caagatggtg tattttctca aaaaattatg ggagagggtg tagctataga
     5041 ttctacagga gacattgtat atgctccaat caatggaaag atagtagtag tagcagagac
     5101 taaacatgca tttgtaatag aattagaaaa tgggatggaa cttcttattc atgttggttt
     5161 agatactgta aatttaaaag gcgaaggttt tgaggcattg gtgagtatgg gagaacaagt
     5221 gaaggaagga acaccaatgt tgaaaattaa ccgtcctttg attgaatcaa agggtatatc
     5281 acttattact ccagttacaa taactaacca ttcagagtac aatatgaata catgtaatgt
     5341 aggcaatagt gttgaaggtg ggaaagatac tgtaattgag tttaaataaa gaattaaaat
     5401 acaaggttaa tatttataaa tacctataaa cttatgtttt ataagattga ttgtatagat
     5461 ttgttgtata aaaaagaact ctttaattat aaattaagga gtttttttta ttttgtaaat
     5521 attgtttaga tttatataga aaaacactta gtaataaata gaataaataa gtatttatat
     5581 agctaaaaat ctaaatagtt ttgtttaaat atatttttat attttgtaat ttcaaattaa
     5641 taaataatta gatttgataa acgaaaaata aaaatgttga ttatattaat aaactttaat
     5701 ataatatatt tatgaaaagc gtaaattgtg aaatggaggt agtaacatga aaattgaaaa
     5761 tctttctatt gatgatatta aacgaggcta tatatttaat gatgatttaa attgttatag
     5821 ttgcattaaa tgtacaaaaa catatgaggt aggagaaata tataaaatag gtaatagatt
     5881 ctttgaagct tcaaaagcta ttgaacttca tatggaatta gaacatagtg attatttaga
     5941 gcaattgctt aatagtgatt caaagtacaa cacattgact gaaaatcaaa aacaattatt
     6001 tcaattattt attagtgatt taccagataa ggagatagca aaacaggttg gagtatccac
     6061 atctactata cgccatcaaa aatttatttt cagagaaaaa gcaaaacagg ctaagctcta
     6121 tttagcacta tatgaatctg tatttgaaga taaatctaat aaaagtagta ctataatacc
     6181 aatccatgaa catgctcgaa tggtagatga aagatatgta gtaactgaag aagagaaaaa
     6241 acacattttg gatacatcat ttgaaagtat gaatccttta aaattaaaag tattttcttc
     6301 aaaagaaaag aaaaaggtcg taattttatc taagattttg gaacaatttg aacgtgggaa
     6361 gaaatattca gaaaaggaag ttaatcagat tttagaatct atatatgatg attttgcaac
     6421 aattagaaga tatttaattg agtatagttt tatgagtaga aataaagaat gtacaaagta
     6481 ttggttaaca taattaaaac aataaatttt actaatgtgt aatgttattt ttatctaggg
     6541 gggaggagtc aaatatgaat gatgaattaa aatctatttt atacaataaa ggtgtagaca
     6601 ttgttcgctt tgttgatata tctgaatttc caataaatca aacacaaggt ttttctaaag
     6661 caattttatt ttgtataggg ttatcaaaaa aatttattac agatatatac aataacttac
     6721 ctacagatag tgatgagttt ttggaaaaag aggagaaagt agaagaatta gctgactgga
     6781 tttcaaaata tattcagaat aaaggatata gagcgtattc tcaatcggag aaaaacaatc
     6841 tagaacatgg atattttgaa aaagcctata ttaatccaga aatgcaatca gggattagtc
     6901 ctttaccaca taagacaata gcaaatatta gtggcattgg atttatggga aaaaataatt
     6961 tgtttgtaac agaggaatac ggatgtgctt ttagcatgtg tacagtactt acagatgctc
     7021 caatttctgt tgaaagatat cctttgattg attcaaaatg tttaaattgt aatgtttgtg
     7081 tagagaactg tcctgcaaaa gctatacatg gaaatgaatg gactttacct ggaaaaagag
     7141 aatctattat tgatgtttca aagtgttttt gtgcattgag gtgtatgatg agttgcccat
     7201 ggtcattaag atatgcaaat caaaaataac tttactagag aaggtattaa attgaatatt
     7261 ataaaatttt taaaatgtaa gattatataa gatttctcaa aataaaaatt tgtatagaac
     7321 actcagaaat gagtgttttt ctattgggat taaattatat tgatacaaag cttaactatt
     7381 ttaatcatta tataaaattt gtattaaaaa attaagaata acttgctaat agtaaaaata
     7441 taatgagatt ataattgatt tataatataa ctgtaatgat gttgtaaaat gaaaattgtc
     7501 atctcaaaat tcctaaaaag agtaaaagtc acttcggtta tagtcaaaaa attttttctg
     7561 tgaaaagaat ttagatttaa aagggaggaa ttaatcatgg aaattgaaac taaaactcca
     7621 gattggatta atgtactaga attaaacagt aaaatagata ttactgggaa atatgatgta
     7681 agtaatatga tacaagatat tgtctctgat aagtcactag aaggttccat tatatatttt
     7741 ccaaaaggta attacttatt tgagaaaggt attaaaatta gtcaacaaat aacacttcaa
     7801 ggagattctt attatggagg agataatcaa gtatcaaatt tagataacaa acaatcaatc
     7861 gtaggaacaa ccaattttat aacccgagga gtttctaata taagtattat tacattggaa
     7921 ggaacaagtc aatgtatcaa aaatattaat ttttattatg atagtcatga tatagagaaa
     7981 ataccaccta aaaatgtatc tgctattaca gaatatggag aaacacaagg actatttcac
     8041 tttgaacacc tgtttatttc tggattttca gggataggga ttgaaattcc atactattca
     8101 actggcaatg atatcattgt tagttcatgt ggtcttggta tgaggcttgg agagaagtca
     8161 atgctttcta gtagcaagat ttatgaatgt aaaaatggaa tggagattac tactggtgtt
     8221 agcttaaata atgtgagaat agaagaaata agagaaatag gtattaataa taaaggattt
     8281 ggttttaacc tgattatgaa tcttatggtc gaccaatgtg gatattgtgg atttatgttt
     8341 gaaaaaatgt gttatagcca gataactgcc agaattacta aatgcggtca gtattataaa
     8401 agtgttgatt ataatactta tgagaatatg gaagatagaa aagaagaagc ttattccatt
     8461 ttttatggag atattttaga aaattgcaat attgtattga tgaatagtaa tattgatacc
     8521 ttagaaaatg attcacttga tgaacataag atatatgtaa tcaaggcaaa tgaaacaaac
     8581 aaagtaatgt taacatgtta tgctgaagca gatgagctta tacagtgcgc aaagggcaac
     8641 ttgttgctag aaaatggtga aaatacttat aaattttata atggtgagat ttgttctgta
     8701 ggaggtgttc aaatttctga tatagatgaa aaagatttaa tcaaaataat cgagaacact
     8761 ctgtatatag atgataaagg taagtactta atggttccta gattaaaaaa gaatactgta
     8821 atatattcag tactagattc tatagaagaa ataaataaat tacatggtgg aatatgggaa
     8881 cagattgatg taaaagtatt agctggggaa tctatgtact attataaaaa gataaaagat
     8941 taaattatca aactaggagg tagtgattaa tggaagagtc tataataatt aaagatataa
     9001 gtggctggat taatgtactt gattatggga tttgtaatga tgaaacaaaa gatgtaagtt
     9061 ccaagttgca agagattata gatgctgcac cagaagattc tattatatat tttccaaaag
     9121 gaaaatactt atttgaaagt ggtgttaaga ttaagaaacg attaacctta tgtggagatt
     9181 cttatatttt ggcgaatgtt cctaaaaaca ctgctggagt aacacaattt acttttaaag
     9241 gaaagaaaaa tcctaaaagt gaaaatatag caattataac agcaaaaagt gtaagacact
     9301 gtattaagag catttgcttt tattcagata gttgtgatag agatatgaca tctaatcatg
     9361 aacctccaac agatggaaaa cctagatttc atcataatgt aattataaat tatagaaata
     9421 tatcggctat tgtatgtgaa gataaacagg gagaaccagg tcattatgaa aatctgtctt
     9481 ttagtggttt ttctggaagt gcacttgata tgcctaataa ttctacagca aatgatatta
     9541 cagtttttac atctggactt ggaattagta caggagaaaa ttcaacgatt gctaacagta
     9601 aggtttgggg ctgtgttgat ggaatgataa tttctactgg aacttttata aatggtatga
     9661 gggtagaaga aataaaaaaa gttggaatta aaaatattgg tagaggttta aattttatta
     9721 caaatatcac aattgaccaa tgtggatatt gtggagtttg gtttgattct atatccaatg
     9781 ttcagatatc aggaaatatc acaaggtgcg gacagtacta ttatgatgta agctatgata
     9841 attatttaat gttggataat agagttaaag aagcatattc tttattctat ggtaatttat
     9901 tggagtcaag taatatagtt ttgtcaaata ccaataaaga taattgggaa gatttcaaag
     9961 aggataagca taaggtgtat cttgtagaag cacttgaaac caagaatgta ctattaacat
    10021 gcaatataga tgctactgac tggattgtta agtcagaaaa gggaaattta acgtacaata
    10081 atatgcgaca aactgttata ttttacgatg gaaaactaag tagtatcaat ggaattggta
    10141 tatctgatga agattatggg gataaagtca agataaaaaa aggaaatata tatataaata
    10201 gtaaggataa ggttattaag atgcataaac cagaggtagg tgacattatg tcaacaatta
    10261 ttaaagatga aaatatactt tccgctcatt atgggggaac atgggggaaa attggtgaaa
    10321 aaatagagtt tggaataact gtacactatt ataaattgat agagaaataa gtaaatacgt
    10381 agtatttgaa tagatgtatt ttattggaga gctaggacta tagttttaat gtaaatggtt
    10441 tggtaatagc atggattgaa taatataaaa ataatataaa aaattaattt gattatgtaa
    10501 aattctatga agtagtaaac ctgtgacttt agtcatggta ggttcaaatt aagtaaatgg
    10561 gaaaggaata tataatatta tggaaggaag aactgggatt aaagatggaa gatggattaa
    10621 tgtagtagaa agaggtatta aaaatgatgg ttcgtacaac ataggtcctg atttacagga
    10681 tattattgat gaaatagaaa cagatttttg tgtcttatat tttccaaaag gaaaatactt
    10741 atttacaagt ggtgttaaaa ttaataaaga aattgtatta caaggtgatt ctaattcacc
    10801 tacagagact acacaattta taactcgtgg agtagaaaat atgagtatta ttacattgac
    10861 agggaagaag caatgtatta aaaatataaa tttctattct gatagttgtg agatacaggt
    10921 aaatgaagaa ccaccgacaa aaggtaatcc taaatatcat tatgagatga ttattaataa
    10981 gaatgaaaaa aatgttgaga tgaataatgt atcagcaatt ctgtatgata atagtaagaa
    11041 tatgattaaa ggtctaggtc attatgaaaa tatttatata agtggttttt cgggtacagg
    11101 aattaggata ccatattact caattgtaaa tgatattaca gtttcatctt gtgggttggg
    11161 tattgataca ggaatagaca caattatttc taatagtaga atatctaagt gtcaaaatgg
    11221 aatgaggatt agaactggaa ctagcataaa taatgtaaga attgaaaaaa tacagaaagt
    11281 tggtcttata agtagtcaag ttaaggatta tgagggatat ggaagttata aaattaataa
    11341 tattacgatt gaccaatgtg ggtattgtgg ttttttattt gactcagtga aaggtagtta
    11401 tttttctggt attataagaa gatgtgggca gtattattat aatacagatt atgacacata
    11461 tttaagtatt aaagatagag tagaagaagc atattcttta ttttatggaa attattttac
    11521 agaatgtaat attgatttag ttagtgataa taaggataac tgggatgatg gcttagaata
    11581 taaacataaa gtttatgtat ttaaaaccct tcaaatacca aaattaacat tgagatgcaa
    11641 tatagatgcc tatgattata tcgttaaatc ggtacatgga ggaggtaatt taatgttaaa
    11701 aaataacttt aacaattata tatttattga ttcatctagt ccagaagtta ttaatggaat
    11761 taattttaat tatcaaaaga atggaaacct gttaaggtta aataatggta aattaagtta
    11821 taaaaatgga aaggaagaaa cagctatatt cagacctaat tatggtctta ttgtagcatc
    11881 aacagattca gaatgtgaac aaatagagac tagctatgga ggaaaatggg agaagcttgg
    11941 ttctgaagta attggaaaag aaacggtata ttattataaa catcatgaac cagataaaac
    12001 aaaccaaata aaataaaatt tgtattatat aatgatataa agttttaata tatagtgttt
    12061 acctttaatg taatattggt atatttgtat agtattaaat ttgttaaaaa gtaaaattgt
    12121 agggtgcttg aaaatagcac cttttttagt ttcattataa aattagtttt gaaagtttag
    12181 gaataatgta tatttatttt taaagaatta taaccttatt aaggatattt taaatgctag
    12241 aaatgaatca gtaaatcata ctggaattat cttaaatgtt ttgattaaat taagtattta
    12301 gagctataat tatattaaaa atatattagg acataattat attactatgg aggttaaata
    12361 tgatagtaag tgtgagtaga agaactgata tacctgcttt ctatagtaag tggtttttta
    12421 acagacttaa agaaggtttt gtttatgtaa ttaatccaat gaatccaaaa caggttagta
    12481 agatagagtt aaatccacat actgttgatt gttttgtatt ttggacaaag gatgtaactc
    12541 caatgttata tgatttaaat aaattaaaag actataaata ttattttcac tatactataa
    12601 catcatatgg aaaagaagta gagacatgta ttttagataa aagaaaggta atagattcat
    12661 ttaaggaatt gtctagaaaa ataggcaaag aaagagtaat tttaagatac gacccgattt
    12721 tcttaagtga aaagtacaca atagattatc atatcaaagc atttgcgagt ttatgtaatc
    12781 agcttgatgg atttacagaa aaatgtataa taagttttat cgatttatat aagaaaacaa
    12841 aatttaatac taaagcatta catataaagc caatagaaat tacagaaata gaaacattat
    12901 caaaagaaat ttctaagatt gctcataagc atgggataat acttgaaatg tgttctgaag
    12961 aatataattt aagtaaattt gggattggaa aaagtaagtg tattgatgat agattaatat
    13021 caaaaattat aggatgtgaa gtagaggtaa aaaaagatag tacacaaaga gatatttgtg
    13081 gatgtgttaa aagtgtcgat ataggacaat acaatacttg cagacattat tgtctgtatt
    13141 gttatgctaa ctttaattat gcaaaagtag aagaaaactg taggctttat aaagaagata
    13201 ataaattact catagatact ttaagagatg atgcaaaaat aagcattaga gatatgaaga
    13261 ctattaaagt agataagaat aaacaaatta gtatatttga ttaaaataaa tatactaatt
    13321 accttaatat atcaagaata tagatacttt tgataacaaa attaaactta atagatattt
    13381 tctatataag aaagatggtc ataatatgtc aatttgacca tctttttgat ataattaaaa
    13441 tacaaataat ttagtaacaa aggaggcaga acttgaattt attaaaaaaa tatcctatac
    13501 ctattgcaag tttgattttg tcaattttta ctttaggtaa cttattacaa tcttatagtg
    13561 aatcattacg taatgtaatt ggatttatag gatttatttt gtatgcaatt tatatagtca
    13621 aaataatatt acttagaaag ggtgttaaag agcaattaga gaacccttta atatcaagta
    13681 catttccaac tataacaatg gcaacaatga tatttgctac atatataaaa ccattatctt
    13741 tagaattaag tattatgatt tggagcatag gaattgtggg tcatcttgtg ttaatagttt
    13801 tatttagtaa gaagttctta gttaaattct caataaaaac ggtatttcca tcttggtata
    13861 tagtatatgt tgggatagtt gcagctagtg ttacggcacc agcatttaat caacttttga
    13921 ttggcaaaat tgctttttgg ataggatttg tatcttatat agttcttata ccagtagttt
    13981 taaagagagt atggataatc aaggaaatgc ctgaaccatc tttaccgagt atagctatat
    14041 tagctgcacc agggtcacta ttattgtctg gatatattaa ttctttttca gataaaaata
    14101 atgtagtatt atacttgtta ttcatattat caattgtatt ttatattata gttttgggat
    14161 acttaccgaa attattaaga ttgccttttt atccgagttt tgctgcattt acattcccta
    14221 tggcaataag tgcaatgggt atgaaactaa tgaatggtta tttaactaaa tcaggtcatt
    14281 ttataagttg gatttcatat gcttctaagt tagaagagat aattgctaca gtgattattt
    14341 tatatgtttt agttttgttt attatatatc ttagtaaatc tgaaactaca tctaaagcta
    14401 aataagaatt attaaatatg tgtatttaat aggaatattg atataaatat atgaagataa
    14461 gataaaccat agaaacttaa tttagcttaa ttttattgga ggaaaacaaa tgaaaacaaa
    14521 agaagaatat ttaaaagaag ttagaaacat atcagaagaa tactttagaa aaggagagtt
    14581 tttttgctct gaagcagttc ttcagacaat aaatgatgct ttaggccaac ctttaagtcc
    14641 agagataact aaattagcat caggatttcc gataggactt ggaaaagctc aatgcctttg
    14701 tggagcgata tctggaggag agatggcttt aggtatagta tatggaagag tacatggaga
    14761 aactatgaat ccaaagatgt ttgagcatgc taaaggtttg catgattata ttaaaaaaga
    14821 gtatggtgca acatgttgta gagctattac aaagaaatgg gatggtgata actttatgtc
    14881 tcccgaaaga aaagagcact gtattaaaat aacaggtcaa gttacagagt gggttgcaga
    14941 taagcttata gaagatgaaa aacttaatat caaatagtgt aatattagtt ggtgaattta
    15001 taaagttaaa tttacttata gtataagata cttgatattc tcgtattgat agaaaaattt
    15061 atagcatatg tatttaatga aatatactta tatttagagt gtggtttaat ttcataaata
    15121 catatgctat tattttaagt atataagcaa atttatttaa ataaatagaa acagttaatt
    15181 tatatgtaca aaactatata tgattagtgt aaataaatac ctattttata atactcaaca
    15241 taaagacacc agacatgatt agtattatac caataaaaat agcaagccat tcttttttgt
    15301 tcttcttttc tttaaaaaat ataatccctc ctaaagtggc tactatcaca caactctgag
    15361 agatagaaaa acttattgta actcccaatg tattagtcgt tatgaacata cctaaatttg
    15421 ctattgacca caatatacca gtaattaaat tgaataaaac attttcccta tatacaatct
    15481 ctttagaaaa atacttgaca ataatagatg aagttatcaa cataccaaca gattgaggta
    15541 atataattct atatccttca attaaaaata tttgattagt tacaacatat aatgataaaa
    15601 atagagatga taataataca actccaacac attttaacat atttttatct gtagattttt
    15661 tagtttgata attagtgaga agtataccaa gtattataca taatattgat aaagaaccaa
    15721 tcagtaacat tttagaactg gtccattcat taaacaagat tacagctaat aatgtcgtaa
    15781 aagttaattg tgaaccattt gaaattggca ttactttaga tacactagca atttgaattg
    15841 ctttaaactg cattaattgt cccaaactcc agaatatgcc agaaatcata cttatacaaa
    15901 atgaaaaaaa tgtaatttca ggatgtataa ccagagttat tatagtggaa aatataaacg
    15961 cacttatgga tgtacctaaa agctgttcat gaggagaact tttctttaga tttgcaacta
    16021 tgggcatcaa tccccatccc attacaggaa gtaaagcaat aattattgtc agcattaaac
    16081 tatttccttt catattaaat ttagacagct tttaatttat catctaaaat taaagtgttc
    16141 aatacataaa aattaccgta tttaatcagg aaatattagt agttttttag aaaaacattt
    16201 tccattaaaa taaagataaa gggaaggagt aaaattgaaa atgttaactg atatgattca
    16261 aaatcgtgaa attaaaataa taaagttttt attaaaagaa ggtcatacaa ctgtaaaagc
    16321 aatagcagat gatttagatg tttcagaaaa aacagtttca aaatctctta aagaagtaga
    16381 agcagtgctt aaaaagatag gtctttcttt aataagaaaa cctaagatag gtgtttatat
    16441 tgatggagat ttaaaaaaaa tacttcctta cctagataat aaaggaagtc aaattcctac
    16501 aaccagagag gagagagtta tctatatata ttcagtactt ttaaagagta atgattatat
    16561 tactatacaa caactttctg atgaactata tataagtcgt ggaactattg aaagggattt
    16621 agcagaagtt gaaaaactgc taaaaaacga agggatttcc atatataaga aacctagtaa
    16681 gggaataaag ttaaatataa gtgaaagaga taaaagacaa cttactgcta agtttataca
    16741 taaattttgg agtagaaact ggtatattaa gcaagagcaa gaaagctttt atcaagcatt
    16801 tgaaaagata caggcagatg taaatggtat tttttcggaa gatgatttat caataattat
    16861 tgatattctt aggaatttca gcagagaaag aaaatttgag ttctctgatt atgaatttca
    16921 gtcattagtt attcatttgg caatagctgt agagagaatt agaaaaggcg aatatataga
    16981 agaaagtttg tatattggta atatagaaaa taatcaaatg tcaaatacca attatttagc
    17041 aaaacaatta gaagaaaaat tttcaatatt attaccaaaa tctgaaattg gatatataaa
    17101 tttacattta gtagcggctg accaacatag agatactaat gaactaaaaa atacttcaac
    17161 taatccttgt gaaacaagta caaataatat atcaaatctt cgggaaatta taaaaaatac
    17221 attgtatgag acagcttatg acaaggattt aattgatgga ttgacttcac atgtacattc
    17281 atcaataaat agactgaaat atggacttag tattaaaaac ccatatgtaa atacaatcaa
    17341 acaaaacttt tctttatcat ttgagcaagc tttagattta aagaaagtaa ttgaatttat
    17401 atatgatatt agaataaatg atgatgaatg tgcttatata gcattacatt ttgaagcttt
    17461 tagagaaaga atgaaagaac ttccacaaaa tattagagta attctagtat gcagtacagg
    17521 attaggttca tctaggttat tgtctgcaag aataaaaaaa tactttccaa tgataaagat
    17581 tgaaaaagta ctttccgtac aagaattagt atccagtaaa attgatgcag atttagtaat
    17641 aagtactatt tatttagagt tagaaacaat tccaaccata gtagttagcc ctattttaaa
    17701 tgaaagtgat ataagaacct tggaaagaaa tatacaaaat gtttcatgtt gtacttctaa
    17761 gaagtataaa tctttcagaa acctaatctt tgaagaaaat atattgttaa atattgaagc
    17821 ttcaaactat gaagatgcaa ttaagtatat aacagataac ctaataaaaa aaggttttgt
    17881 aaaagaaggt atagctaaaa gtgcaattga gagagaaaat ttatcttaca cgtcttttca
    17941 gtcaatagct acacctcatg ctaatcctag ttatattaaa aaatctaata tatctgttgc
    18001 aacgttaaaa aatcctatta catggggaaa tgaaaaggtg gaagttattt tctttatttc
    18061 attagaaaat gacaaaaacc tagagcttga tgaaatatat gaagtttttt atgactttat
    18121 tgacaataaa aaaaatataa atgacatatt aagtgcaact tccacaaagg aagtgtacga
    18181 tttgctattg gaggagagta tatagtgaaa atatcagatg tattgaaaaa agagcaaatt
    18241 gtttttaatc ttgatacaaa tacaaaggaa gaaacaataa aaaaattaag tagtatattt
    18301 gttgaaaatg ggattgtgga caatgaagaa gaatatgtta agtctgtttt ggaaagagaa
    18361 gaacattcaa ctacaggtat tggtaatggt attgctattc ctcatggaaa aagtgatgct
    18421 gtcaaaaaat cttctataat atttgcaaag actaagcata agattgagtg ggatgcttta
    18481 gatgaaaaac cagtagatag tattttctta ttggctataa gcaatattga taaggatagc
    18541 aatcatcttg tactattatc taaattagca actaaactta tggatgatga caatgtagat
    18601 gcactaaaat tagccaattc agaacaagaa ataatcaata tatttagtga agaaggagag
    18661 atgtagaaat gaaaagaaaa attatagcag ttacagcatg tgcaacagga gttgcacata
    18721 catatatggc agctcaagcg ttaaagaaag cttcaaaaaa gatgggtcac cttataaaag
    18781 ttgaaacaca aggagctaca ggaatcgata atgagttaac tacaaaggat gcacaaattg
    18841 cagaagtagt aatatttgca gtagatacta aagtcagaaa tgctgaacgt tttgagggaa
    18901 aagaaatact agaagtacca gttaatgcac ctataaagga tgcagagaaa gtaataaatg
    18961 atgcattaaa gttaattgac actaaataaa tggagggaaa tgtaatgttg aaaaagatag
    19021 tctctgagtt aaaaaagcat gtcttaactg gaatctcata tatgattcca ttagtaattg
    19081 caggtgctat gataatggca atatctcgtg taggtggttc tttctataat ataccagata
    19141 tatgggatgc taaatacgca gaaagtgcta gtagtattgt tagattatta catgatttag
    19201 atggatttgg aggtactgca ttaggattaa tgtttcctgt aattgctgca tttataggat
    19261 tttctatagc tgataaatta gctattgtac caggtcttgt tggaggtatg attgctaaag
    19321 atataggtgc aggattttta ggagctttgg cagttggtct tatagcagga tatacatgtt
    19381 tgtttattaa aaatcatgtt aaattaccaa aatcagcagc ttcaatagta ccaatattta
    19441 tagtaccagt atttggaaca ttaatcactg ttgtattaat caattatgtg ataggtatac
    19501 cttttgccac attaaatact ggattagaaa attggttaaa tggattatct ggtacaaatc
    19561 agatattaat ggcagctatt ataggggcta tgatggcagt tgacttaggt ggaccagtta
    19621 ataaagcagc tttaacaaca tcacttgcat tattaacaag tggaatttat gcacctaata
    19681 ctgctgcaat ggtaggaata gttataccac cactaggatt gggacttgct actatactag
    19741 caaaacaaaa atataataaa cagttacgtg aagctgggaa atcatctctt ataatgggtt
    19801 taattggagt aagtgaagga gcaattcctt ttgcggtaga atctccatta aaagtaatac
    19861 cttcatgtgt aattggaaca gcaattgctt cagctatggc agttggttta ggttcagtaa
    19921 atgcaactcc aattagtgga ttttatggat ggtttacagt agagaattgg ccaatgtatg
    19981 tgttatcaat agcagttgga acagtaattg tagctggatt agttatagta ttgcgtggaa
    20041 atccagtgat tgaggatgat gaatttgaag atgatgattt tgatgaagca gagtgggaat
    20101 cttaaaattt aataactatt taagacgtgt tataagctat attcaatatg aatcttatac
    20161 taaataaagt gttaaatatt cagtttagac ttaaatataa aagataaaga acagaggaga
    20221 ataaatgata aaagcacata ttgttaatca tacacactgg gatagagaat ggtattttac
    20281 ttctggagat gcattagtac ttagtgaaca actatttaca gatgtaattg atgaattaga
    20341 acgtaatcca gatgtaagtt ttgtacttga tggacaactt tctattttgg atgattatgt
    20401 acaattacac aaagaaaaaa tagaaatcat taaaaagtta ataaaagaag atagactaca
    20461 tattggacca tggtttactc aaactgatgc attctttgct agaggagagt ctattttaag
    20521 aaacttaatg attggaattt ttgaaagtaa aaagtatggt aagtatatga aaattgggta
    20581 tttgccagat acatttggat ttaatgcaca gatgcctata ctattaaagc atgtaggtct
    20641 tgataatata ttcttttgga gaggtataca tcttggtaaa catgttcaat caccatattt
    20701 taagtggaaa agcttaaatg gagaaagtta tatatatgca gtaaatatgc cacatggata
    20761 tggaactggt atgcttttag agccttcatt aaagtatgtt aatggacgct tagacccagc
    20821 tgttgatttt attaaatcat atactgatgt agatgaggtg ttaatacctt ctgggaatga
    20881 ccagttaaat ataataggtg atttcaaaaa taaaattaaa gcgattaatg atatcggaaa
    20941 gtattcatat ataacgagtt catatcaaga gtttttaaaa tatataaagt ccatagaatc
    21001 actagaaagc tatagaggtg aatttagaga acctgtatta gcaagaatac ataaatcaat
    21061 tggttctagt agaatggata taaaattagc atgtgataaa ctagaaaaca agctgattaa
    21121 aagaatagag ccattattag taattgctaa aaagagtaaa attgaaataa gcaatcagtt
    21181 acttataaat acatggaaaa aacttttgga aggacaagca cacgatagtc tagctggatg
    21241 tgtaactgat actgtaacag attatattct tcaccgtata agagaagcaa atgaaatatg
    21301 tgacagtatt gaaaatacta ttgtaaaaaa gatttcagaa gggcttaaat tatctaaaaa
    21361 tgatatttta gtatttaata cagaagctaa gcgttttaat ggatataaag agatacaagt
    21421 tgtaagtgat agtaaaaata tttattttaa atataattta gatgctacta taattgaaga
    21481 aacttatgta aaaccgagag aaaatgtatt agaagaaaca cctgctggca acgtatttat
    21541 tgaagaacca ggatattata tattaaaagt aagaataaat gtacagcttc ctgcacttgg
    21601 ttataaagtt gttagttttg aatcaagtga taaagaaatg gtatcacttg ataaatctaa
    21661 tgacactttt atatctaatg ataattataa gataatctat gaagatggaa gcttaaattt
    21721 acaacttaaa gatggaactt acatatcaaa ctttttaata ttaaaagata gtggtaatgc
    21781 aggcgatacc tatgactttt ctccattaaa aaatgacgag gatataaaac tttcatttga
    21841 tagagtgtat acagaaaaag ctttaggata tgaaaagttg gtggttaaag gtactacttt
    21901 actaccactt acattagaag atagaaaaaa caaatatctt aatgggaaat taaatgtaaa
    21961 agtaagtatt gtcttatcca aagaaaatcc attgatggat gtaaaacttt gtgttgataa
    22021 cacgatatat aatcatagac tacgtgttca tataaaaact gatataaaag ataataaaaa
    22081 catagcatca ttgccatttg gatatataac aagagaaaat ggagttttag acaactggga
    22141 ggatatttac agtgaaatgc ctatagattt agaacctttg gaaagtaata ttactctaac
    22201 aaaccaaaat agaagctgta ctgtatttac tagaggaata aaagagtatc aacatattga
    22261 agatgaaatt gcattgacct tacttgctac tacagatgaa ctaggaaagc ctgatttatt
    22321 atatagacca ggacgtgctt ctggtgatac aactaaaaaa ggtcatataa gaattaaaac
    22381 agataaagct caaatgctta agaaattaga attttcattt gcaatatata tggattctaa
    22441 atcatttgat gaattggaaa ttgcgaattt aacccacaat tatctaaggg aatgtgtaaa
    22501 ttatcaatta caggattaca atttcttttt atatcgtata gataataaga ttcaaaaatc
    22561 aattgtcaat aaaactataa gtagagaatt agaaataata tctttaccag aaaaatatct
    22621 tatatcagca tgttatcctt cttattacag taaagataaa tttataataa gagtggaaaa
    22681 tccaagtagt aatagaatga tattggatga gcaaatattt aaaaatagaa atgggaaaat
    22741 tgtaaatgca atagaagatg tagaagaaga acaggtatat gaaatagcac cttttgacgt
    22801 tatttcaata ttattggatt tataagtgta aaagtaagtt tattgtttaa agtctgacag
    22861 atattaatct gccagacttt ttaatttgta taaatttggg taaatattaa tgaatagttt
    22921 tagtatttaa atatgaattt agtatttaat atagaattta ttgaagtaga ataattagtt
    22981 taacaggata agcagtttaa ataaagaatt attatattag agtgatttta tatataattt
    23041 aaaataataa aatgttaata aaatgagtta aagattgtat attaataggg ttgatgtagt
    23101 tacaaaaaag ttaccaattg ttatgtattt acaaaactga tatattaatt acataaaatc
    23161 taaaatagtt tgtaatagga gtatatataa taaaaatttt aattaaataa agctaggtat
    23221 atttataata ttaataaata tattgctata aaagtttgtt taataaatta aataaagaaa
    23281 agaggagaat aaaatgtaca acatagatga tatgatatat aattgtccag tagaagcttt
    23341 atcaaatatt ttaggtaaaa aatgggtggc tataattata tggaaaatac aagaagataa
    23401 gaaacgattt ggagagctac aaagagctat accagactgt agtaagaaaa tgttagttca
    23461 acaactagat tttttaattg aacaggggat tatagtcaac caaaaaaagt tggttaataa
    23521 tgttgtagag tcaacatatt ttttaagtga atcaggatta cgattgcttc ctgtcatgga
    23581 aaaaatgatt atgtggagca ataaaaattt aaattgtgat aaatactaaa atttactctg
    23641 taagtaatga aaatttaatt aagctatgag tagaaaaatg tattaaaatt acataatttt
    23701 ttagttagat tttaatttag aaatgggatt gtaatattgg aaataaaata aggaggaatt
    23761 ttaatttgca aaatgtaaat ttatttttag tatttataga aggtatagta tcattctttt
    23821 caccatgtat actgccaatt ttgcctattt atttgagtat attgtcaaat agtagtgtag
    23881 aaaatctaaa agaaggaaag acgagtttta taggaagttc tttatttaaa aatactatat
    23941 tttttgctct tggaatctca acaacattct ttatattggg ttcatcagta aaagcattga
    24001 gtatgttttt taatgaaaat aaagatttaa taatgtttat tggtgggatt ataattatta
    24061 tcatgggatt attttacatg ggaataatta aatcttcaat attgaataga gaaaaaagat
    24121 ttaatgttaa gtttaaagaa atgaaagcaa taacagcttt tatattaggt tttacgttta
    24181 gttttggatg gacaccttgt attggtccaa tattggcatc tgtattagtc atggtttcaa
    24241 gttcaagtaa tcatcttagt gccaatcttt taatagcagt atatactatt ggttttattt
    24301 tgccatttat aattacagct atgttttaca gtaaactatt taaaactata gataagataa
    24361 aatctaacat ggaaattatt aaaaaaatag gtgggattat acttatagta tcaggaatat
    24421 taatgatggt aaatggattt ggaagtataa gcaaacactt taatacgtca caaaatagca
    24481 aaattgaaag caagcaagaa gaaaataagc gagaaaattc tactgataaa gaagaaaatt
    24541 ctgatggtaa taatagtcaa aaagactcta ataatgacaa taatgataac gggtctaatg
    24601 atgaagatag aataaagtct attgatttta ctttaacaga ccagtatggt aaaacacata
    24661 aattaagtga ttatgaaggc aaagttgtat tcttaaattt ctgggctaca tggtgtcctc
    24721 catgtaaaga agaaatgcct tatatagaac aactgtataa agactataat aaaaacaatg
    24781 atgatgtagt aattttagga gtagcttcac ctaatttagg tagagaaggt tcaagggaac
    24841 atgtagttaa cttcttaaaa gaccaaggtt atacattccc tgttgtactt gatgaagatg
    24901 gagcattagc atatcaatat ggaattaatg cttttccaac tacatttata attgacaagg
    24961 aaggatatgt aactcagtat attccaggag ctatggataa ggcaactatg gcatcattta
    25021 ttgaaaatca gagaaataaa taaaagtatt taagtatatg tttatgaatc aatttaaggt
    25081 tacaaaaaag tgcctaattg taccacctaa ataatcttgt tatagtaaaa gtataaacaa
    25141 tacaagaaag ggttgaattt tatatgaaaa aaacatttga tgctataata ataggatttg
    25201 gaaaaggtgg aaaaacatta gcaggagatt tggcaaacag gggattaaaa gtagctttaa
    25261 tagaaaagtc aaacaagatg tatggtggaa catgtgtaaa tgtggcatgt ataccaacaa
    25321 aaagcttaga aaattcagca aacagcgtaa aaacaaagaa tataaattct tgggatgaag
    25381 tacaagctga atatgagaaa gctatagata aaaaagaaac tttaattaca aaactcagag
    25441 aagctaacta taataaatta aattcaaatg agaatgtaac tatattcaca ggaatgggaa
    25501 ctttcattga tgaaaaaaca gttcaagtca aaactgaaaa tgaaatttat gagttagtag
    25561 cagataatat atttattaat actggttcaa gaccatttat acctaatatt aagggaattg
    25621 aaaataagaa tatagtatat gatagtgagt ctcttatgaa tctaagagtt ttacctaaaa
    25681 aaatgacaat tataggagct ggatttatag gtttagagtt tgctggtatt tatagttcat
    25741 ttggagcaga agttacaata ttaaactcta ataatggcat tttaccaaat gaagatgttg
    25801 aggattcaga agaaataata aaattacttg caaagagaaa tgtaaaaatt gttaataatg
    25861 caaatataaa agagattaaa gaagtttctg aatcagcaat agtagaatat gaagtagatg
    25921 gtaaatctaa agaattaaca agtaatatga tacttgtagc tacaggaaga aaagcaaaca
    25981 ctgaagggct agggctagaa aatgcaggta tagaattaaa tgaaagagga tttattaaag
    26041 tctcagaaac tcttaagact aataaagagc atatatgggc tataggagat ataaatggag
    26101 gtccacaatt tacttatatc tcattggatg attatcgcat agttattaat cagttatttg
    26161 gagataagac tagaacaact aatgatagaa agaatatccc aaattctata tttataagtc
    26221 cagcattttc aagagttggt cttaatgtta aacaagctaa agaaaagggg tatgaagtat
    26281 tagtggcaaa gatgccagta gaagcaattc caagagctaa acagattggc aaggcagatg
    26341 ggtttataaa aatagtgata aataaaaaat ccaataagat acttggagct agtatgatat
    26401 gtgaaaattc aagtgagatt atccatctta ttcaattagc tgtagattta gaagtagagt
    26461 atacatattt aagagaccgt gtttatgcac atccaactat gacagaagct cttaatgata
    26521 ttctatctcc taatatgata aaagaagtat aacataagtt taatatataa acctaaaatt
    26581 atcattataa gtagatttta gaaagaggct atctcaaaaa atagagataa gtctcttttt
    26641 tactttttaa atgataaaaa tatatttgat tttataaaag aagattatct tatgaactaa
    26701 aaagtttatt ttaaaacact acctatttat gttataaact tataaatata atatagaatc
    26761 tattattctg tattattaag tgaggttaag cgttataatt aattataaat attgaataat
    26821 ctaaatggat aagataatgg tattaaaaat tatcttaaaa ggtgaaataa tctgtattta
    26881 atgtagtaca gttatatctt taaagcaagg tggtgaaatg atataaataa gatatctaaa
    26941 agagggtttg atgatagtga taaaagatgg ttttcaagta aagaattaac aagacttata
    27001 aaggctaaag aagaaataga atggttatta aatagggatt acaaaataga cccagtcgtt
    27061 acttttgttg gtgatagata tcagttttct ataagacaaa gagatgcatt aaaaagggca
    27121 gtctgtactg atgaaaaaaa tattataaga caatcaaaga ggctttctct agataaaatc
    27181 aaagaagata ccgtaaatat agatggcttt aatttgataa tatccataga ggtagcatta
    27241 tctggtggta ctctagtaat aggaagtgat ggcaatataa gagatttagc aggtcttagg
    27301 ggaacctata agattataga taaaacagaa gaagctttga atctgatagg taaaattttt
    27361 aataaataca atgcacagaa tcttaaattt tatttagatg ctccagtttc taattcagga
    27421 aatttaaagt ataggatatt agagcatgcc aaaacttggg gaattgaaac tgaagtagaa
    27481 ttagtaaaaa atgcagatgt tgtattggaa aaattagata gagtagttag tagtgatgca
    27541 gtcatagttg acaagtgtat aagttatttt aatgtggcta gaggtataat tgaagagtat
    27601 attaaagaat gtaatatcat aaatttaaat aaatagataa atagaggtga gaatatataa
    27661 gtatatgtag caatattatt agtaatacaa gtaaagtttg aaaataggag aacgaataca
    27721 tatcgaattt cataaaatgt tgtaaaaaga catatgagag gatggatatg tgtgaaatta
    27781 actaaactaa atattaaaaa atatagagca cctatatata aatatgcttt agcaaatgta
    27841 aatttgaggt ctgctaaatc tactaattca agtatcataa cagtaatacc tcagggagct
    27901 aaaatggaag tattggatga agaagatgac tggattaagg tgatgtacaa ttctcaagaa
    27961 ggatatgtgt ataaggattt ggtatcagta agcgaatatg cttggagtaa cttaaactta
    28021 agagaagata aatctataac ttccaatata attacagtaa ttcctgaaaa atctagggtt
    28081 gaagtccttc aagtagatgg agattggagt aagattgtat atgatgataa aataggatat
    28141 gtttttaatt attttttatc aattgatggg aataaaccaa atgaattaga ttataagtat
    28201 ttttatactg acatgattaa atttgttaac gaaaataata ttaaaagtac tagcgattat
    28261 ctaattgtaa cagaccttag aaataaatat acttatattt ttaagaaaga taatggaggc
    28321 tgggggcaac tttacaagtg gcaatgtact ataggcaagc ctgagactcc aactataaca
    28381 ggtatatttt atataagtgg aagaaaacct tcttttggaa cggatgagta ttcagttaag
    28441 tatgctacta gaattaaagg tggatattac tatcattctg tgctatatga ttcaacagga
    28501 agttatataa tagatggcag acttggtgaa gctcttagtc atggatgtat aagattaagt
    28561 acggaaaatg caaagtggat atatgataat ataccagata caacaacagt tataattcat
    28621 taagaaaaat tttgagtttt tattgggata atgattctca aattaatagg attatatatt
    28681 aacttcttca taaagagtac tatttaaaaa gtgtaataag agagtgctat taacaaaaca
    28741 aagatatttt gaggcactct cttataaata tacataatta agatattttc ataaacaatt
    28801 ctataatctt ctccttatca aagaaaacag gattagcacc agcacaagca tctttcatag
    28861 agttttctgc aagcaattca aaattaggat tatcaacacc tacatctttt aaagattttg
    28921 ggattccaac ctcttcagaa agagctttta tcttatctat tacaaagtca acacactctt
    28981 tatctgattt attatttaca tccattccaa taacttcagc tattggtcgg aatttggcag
    29041 gggctgattt agcattttcc tcctcaacta ttggaagtag catggcatta catactccat
    29101 gaggtaaatc atataaacct cctaattgat gagccatagc atgtacattt ccaagacctg
    29161 cattactaaa ggcaattcca tttaaaaaac aagcataaca catttgttct ctagcttcta
    29221 tgtcattacc atttttaaca gctcttggaa ggtatttaaa tatctgcttt atagcatata
    29281 aggcagttga atctgtaaca tcataagcac cattagctac tacagcttct acagcatgag
    29341 ttagtgcatc cataccagtt gctgctgtta aattagatgg tttgctaatc attaattctg
    29401 ggtcatttac tgtcattgta gctagtgagt tggtatcaac cattatcatc tttacatgtc
    29461 tgtcttcatc agttataaca tagtttattg taacttcagc agatgtacca gcagtagtag
    29521 ttatagctac gataggaaga cattttttag aagttttgtt gataccttca tagtctctaa
    29581 tatctcctcc attagtagct aatatagaga tagctttacc acagtcttgt ggagaacctc
    29641 ctcctatagt tataacgaag tcacaatttt ctgattttaa tattttaagt cctttatcca
    29701 cattagttac ggttggattt tgtttaactt catcataaac aacaaagtct acatctatct
    29761 gagataaaat atctgttact ttttttacag taccatttga aactagaaat ttatcactaa
    29821 caacaaatgc ttttttagtt cctaatgatt taattgaatc tttagcttca ttaagacatc
    29881 ctttcccaag taaatttatt ggtggtacat aataagtgct cataactaaa atctcctttt
    29941 attttcattg atttttatgt aaaaatatat atctaacaat tttcactaat ttactcataa
    30001 tatatcgtat cttagattga gatagggtta ctggttctta tataagaact taattcgtaa
    30061 ttacgattat gattagaatt taacatagta tttttatcat gtcaataaaa atataaaaaa
    30121 tattataaaa aaaacaaagt tactgtagtt aaatcagcaa ctttgttttt atagtataaa
    30181 tcaaataaat acattagttt aaaacaaaat ttttaattat tatgttttga tatcttccat
    30241 atacagaata ttaatctaat ttattacaat gtcttcatta cgttcttcca tcattgattg
    30301 aatatttttc tgagcattta agagtaattt ttttatcagt tctatttttt cgtcattagc
    30361 tctaaataaa ggcagtgtta cactaacagc agctcttata catccatttt ttcttattgg
    30421 tacggcaaga cattttaggt gttccattga ttcttcacac tctgaagcta tttgtgttct
    30481 ttgaacttca agaagctggt cgtataaaac atcaaaatct gtaattgatt tttctgtaaa
    30541 accttttaga ccatctggat ataagcttat tagtttttcc ttgtcaaaat cacataaaag
    30601 agcttttcca agacctgtac aattagcagg tatttttttt ccaacataag aaataagtct
    30661 aattggttct ggagaatcta cttttccaat ataaagaact tcattattgt caagtatacc
    30721 aagctgacaa gtttcagaac aggaattaac tatattagtc atttcgtcaa ttatatagtt
    30781 aaaaatagtt cttttttcaa aaaatgaaga ccctaatgtg taagaacgta tccctataga
    30841 atatttggat gtgtttttat caatagtaat gtattttcta gcattaagtg tatgaactat
    30901 aggaaagatg ctactttttg gagcattgat aacatctgct atttctgtaa gagtatatcc
    30961 attttcggat tctgctaatg cttctaaaat atctaatatc ctagctgttg ggcgatgatt
    31021 atctgaagtc ataaatttcc ccctcttttt attaatttaa agtattagaa tatgttgatt
    31081 ttagcacact atacgatatt ttacaatgta gaaaataaat atgtaaattt atatataaat
    31141 aagctcttga tttagataca gatagatatt tttttagact gtacattaag gaataactaa
    31201 tttccaaaat atacctaaag aaagtaagtg atatttagtt atataattta agtaaatata
    31261 tgcaatagtt atttttatat gtaaatatca aaatattatg aatttatatt ttatctattt
    31321 tttacactgt ataaaaactt tatagttttg aatactatat aattttaaat acgctgtatt
    31381 tttgcatata aggaagtcat ttgataatat acaaggtatt atcagaaagt ttgaaaaaaa
    31441 tttgacaaaa atttattttt tttattgact cataaatagg aaaatgctat cattaattca
    31501 aagattcgta attaaaaact tagttcttaa atacgaaccg aaacggccgt tagaattaaa
    31561 gctaaaaact taataagagt aattaaatat catgttttag gaggattaac tttatgataa
    31621 tggattttat taaaaaaatt cctgcaggta tgatgatagt gccaatgttt atagcagctt
    31681 tcattaatac cttttgccca gatattgtac aaataggttc gtttacgaca gcagtatttt
    31741 caagtgttgg gtctgcaact ataattgggg ttcaactggt atgcttggga actcagcttc
    31801 aatttagaga aatgccaaaa gttttaaaga gaggtggtat acttcttggt tctaaatttg
    31861 ctataggtgc tttgataggt atacttatag gaaagctatt tggaatggat ggtgtccttg
    31921 gtcttacaac attggctgtt ataagtgcag ttacaaatag taatggtagt atatatcttt
    31981 cattgatgac ttcatatgga gatgaaacag attgtgcaac tatgagttta cttactttaa
    32041 atgatggacc attttttaca ttaatagctc ttgggacttc aggtcttgca aatgtgccat
    32101 tgttgtcatt attagctgca atagtgccaa tacttgttgg tatgataata ggaaattttg
    32161 acaaaaaaat gaaagagttt ttagagccag ggtgtaattt actcgtacct tttgtagggt
    32221 ttgcacttgg tagtagcata aatcttgcaa gtatactaaa aggaggttta tcaggagtat
    32281 tacttggatt aatatctgta tttgtaggag gtatatttat agtattctgt gataaattta
    32341 taggaaaacg tccaggatat gcaggatggg ctgtagctac aaccgctgga aatgcaattg
    32401 ctgtacctgc tgctgttgca ttagttgacc catcatggca accatatgtt gcaacagcta
    32461 caacacaagt ggcagccgca gtagttgtca ctgcaatatt agtacctctt ataactagtt
    32521 ggtgggctaa gaagtatgga tgtcctaagt tcccaaaaca aaatgaggat ggtacaataa
    32581 cagcttaatt tatattacag tgagttgttg gtaaaataat aaattcttta attagatttt
    32641 aggatattaa taaaattata ttatttataa aggagagaaa gaataatgat aaatgcagtg
    32701 ataattgatg aaaaagataa tgttgcagta gctattgaag caatagctaa aggtaatgaa
    32761 attagtttta aattaaaaga caaaacagta aaaacgatta cagcactaga taatataact
    32821 atttatcata aattggctat aaaagatatg gcccaaggtg ataaagttac taaatatggt
    32881 gaacatatag gagaagcaaa tcaggaaata aaaagtggtc aacatgtaca tattcataat
    32941 gttagaagtg ttagagagga tttggataaa caagttatga ctaatatata aaataatatt
    33001 tatagagtta taaaagttgt attcattgct tttagtgtca aatagttttt aaataggatt
    33061 ttagctgttt gattagtgag tgtaataaaa attataatat ataaaaatta taaaaagtat
    33121 atagactatt ttaggaggaa atcagtatga aattttatgg atataaaaga ccagatggaa
    33181 gagttggtat aagaaaccac atattaatat tgcctacgag tgtgtgtgca tcagatacaa
    33241 ctagaataat agcatcacaa gttcaagggg cagttacctt taataatcag aatggatgtt
    33301 cacaagtaca ttcagaccaa caattaacta tggatgttat ggctggttat gcagcaaatc
    33361 caaatgtata tggtgtaata gttgtatctt tgggatgcga aaattgccaa aatgatttgg
    33421 tagttgatgc aataaaagag agaacaaata agccaataaa aactcttgta atacaagaag
    33481 aacatggaac tttaaaaact atagaaaaag ctgttcgtta tgctagagaa atggcacaag
    33541 aagcttcttt gcttagaaaa gaagaatttc caatatctga acttatacta ggaactgaat
    33601 gtggtgggtc tgacccaaca agtggattag cagcaaatcc attaataggt gaattaagtg
    33661 ataaacttgt cgatttagga gcaacatcaa ttttaagtga aactactgaa tttataggtg
    33721 cagagcatat actagctagg agagcagtaa atgaagaagt aaaagaaaaa atattacata
    33781 tagtacatag atatgaaaat tcattaaaat tggttggaga agaagttaga gaaggtaatc
    33841 catctcctgg aaatatagct ggtggtttaa caagtttaga agaaaaatca cttggttgta
    33901 tacataaagg aggtcataga caaataagtg aagtatatga ttatgccaaa caaattgata
    33961 agaaaggtct tgttataatg gatacccctg gaaatgatgc ttcatctgtt gctggtatgg
    34021 tagcaggagg agcacaaata gtggtattta gtacaggaag aggaacacca tcaggaaatc
    34081 caatagcacc agtaataaaa ataactggaa ataaaataac ttttgcaaat atggaagata
    34141 atatggattt tgatgctagt ccagttatct atggtccaca aacaatggaa gaattaacag
    34201 atgatttgtt aaatatggtt gtagatgtag caaatggaaa acaatcaaaa gcagagtccc
    34261 ttggatatac tgaaatggca atagctagag tatgcaacta tgtataatct ttaagtaaga
    34321 aaataaatac atagaatttt aataaagggt gagattatga agtttgtaag ttttactgaa
    34381 ggagaaaatg aatgtaaaag aactggagtt ttttctaaag atgaattatt tattatagat
    34441 gttaactctt taaatctcag tagaaatttt aaggatttaa atgaattaat tcaaaatgta
    34501 tctagtgaag atattattaa gttgaaaact attataaatg gaagtatatt ctataattat
    34561 gatgttttta aaagagagag atgtactgta catgttccta tagaaaaacc aatacatgat
    34621 atcttatgtg tgggagtgaa ctataaagac catcttgaag aaactcaaac tcactttgat
    34681 gatagttttg aagaaccaca aaaaacggtt tattttacaa aacgtgtgac aaaggcaata
    34741 ggtccagaag atgagataga tggtcatttt gagataaata atcaactaga ctatgaagtt
    34801 gaacttggag tagtaatagg taaaacaggt gttaatatta gaaaagaaga ggtagaagat
    34861 tatatctttg gttacactgt tataaatgat atttctgcta gaaagttgca aaaagaacat
    34921 gttcaatggt ttagaggaaa aggattagat acatttacct ctttaggtcc atgtatttta
    34981 cataaaagtg cagttccttt tcccataaaa cttaaagtat gtagtagggt aaatggtgaa
    35041 gaaagacaga gttctaatac aggattattc atatcagacg tttcagacat agtttcagaa
    35101 ctttcaaaag gtatgacttt agaggctgga gatattatag ctactggaac accttctgga
    35161 gtagggatgg gattttcacc tcctcgatat atgagtagtg gagatgtagt tgaatgtgag
    35221 attgagagta ttggaatttt aaaaaattac attaagtaaa tgttttaata taattaatat
    35281 taaagctaaa tctgatgtat taatgaacat attaaaataa attttaggag tttaaattat
    35341 gaaagcagaa tttttgacac cagttgttac aatatttgat gaagaaggaa atttagataa
    35401 agaaggtaat aaaaaagtgt acgaccatct tatagatgga ggtgtagatg gactagtcat
    35461 aatgggaagt actggagagt tctttaatat gtctatggat atgcaaaaag aacttataga
    35521 tttagtaact agtcatgtaa ataagagagt aaaagtgttt ataggtacaa gtcgtatgtg
    35581 tataaatgaa tctatagaac tttcaaacta tgcacataat agtggagcag atggcgttat
    35641 gataataagc ccttattatt tctctcttga tgatgatagt attgagttat tttatagtga
    35701 aatagctaag aatacagagg ctgaaatata tttatacaat tatccagata gaactggtta
    35761 tgatttaagt ccagaactta cattaagact tgcaagaaaa cataaaaaca tagttggata
    35821 taaggataca gtaactttga tgggacatac cagagattta ataaatacta tgaaaataga
    35881 gttcccagaa tttaaggttt atagtggtta tgatgaaaac tttatacata atctaatgtc
    35941 tgggggagca ggttgtatag ggggattatc aaatttaatt ccagaagttt gctccaaatg
    36001 ggctgaagct tacaataata gagatatgga gaaggttata gaaattcaaa aatatattaa
    36061 taaagcaatg gatttttact taataaccaa tccatttata ccagcaatga aaaaagctat
    36121 gaatatcaga gggttacaaa taagtgatta tatgactgct ccatttgtaa aaccaaatga
    36181 aaaacaagta tgtgaaatta aaaaattgat gaataaatta aatatatgtt aaatcaacct
    36241 tgcaaagagg tcaacaataa attacaatta tcttaataaa aattaaatta aaataatact
    36301 agggtactag attagtttaa tagggaaagt gatgaaaatt cactacagcc cccgctactg
    36361 tatacggata cgaaatcaaa atccactgaa atttataaaa attttgggaa gggtgatgga
    36421 ggaaaagccg tgagtcagga gacctgccca gtattatata agttcaattt agggtggaga
    36481 ttgtaattta taataaaatg aagtatcaat tcgtttttgt aaagttgata tatgaacttc
    36541 tccttattaa attaggagaa gttttttatt ttattaaaag gttatactta ttaaagatga
    36601 ctttaggata actttaataa gtatacttta aaaagcatat attattaaag ttttttagcc
    36661 actcataaaa aataagatat tggagtgaaa gagatgaaat ttaaatcaaa tgttttaaag
    36721 cagttttttt taattgctat ggtaattttt atggtaggag gtcttatagg gtgtagtaaa
    36781 agtgacaaag agaataaaca agctagtact ggtaagaaat tagaattaaa atatgctagt
    36841 ggatttagtg ttgaagattt agaagatgga attaaaaaag taactgatgg agataatcga
    36901 gaactgattt taatcccaaa gaagattaaa attcctgaaa aatataaaaa tgctaatata
    36961 gttagaacgc ctgtggacaa tgtattaata gcatctacaa cacaggcttg ttctctgaga
    37021 acaatagatg aactagatag tataaaagcc gtaacaacag aagagcagta ctggactatt
    37081 aaagaaatta aagatttaat gaaagatgga aaaatacatt acgttggttc aaatttagca
    37141 ccagattatg aaaaaatagt agacttaaat cctgacttaa ctatagtgag tagtggttta
    37201 tcagaggctg atacaaaatt tattgacaaa ttaaaagaat tagggcttaa ttatgttgta
    37261 gacaatgagt ataaagagca aaatccattt ggaagaatgg agtggacaag tttaatagct
    37321 gcattttatg ataaagaaga tatggctact agtgaactaa ataaaactgt acaaaaggta
    37381 gaagaagtaa gtaaaaaaat aaaaaacaaa gctaaaccta aagttgtatg ggcatctgta
    37441 tatgaaggaa gtgcttatat agctcctaaa gattcatatg tggataatat gataaaaatg
    37501 gctggtggaa taaatgcatg tgcttcaata gattcaaatg aagggcgagt aagtattgaa
    37561 caattgcatg aagttgcaaa agatgcagat atatttgtat actcatcaag ttcagattat
    37621 gcaccaaatt tagattctat aaaatctagt gcacctgtat tggctgattt ggatgttgta
    37681 aaaaacggaa acctatgggt gtttgctcca gattattatc aatcagtaga taagacggac
    37741 gaattaatag tagatttagt tgagatgttc cacccaggta ctacaggtga aaaaatcaaa
    37801 cattatataa attatgataa atagtacaga gaggacacaa aaagataggt tttatagatt
    37861 ttagttaata taactttgct aagaggagta tacaaatgga ttttatcaat aaaatgagaa
    37921 taaggaatac gacaatattt atagtattaa ttataagtat gatacttact tttttagtgt
    37981 gtgtagcatt tggctctgta aaaattgaat ttaaagaagt aatagatgtt gtattaagag
    38041 gtatggataa tacagaacat tataaaataa tatacaatat aagaatccct agagtacttg
    38101 caaccatggt aggtggagca tgcctagcag tatcaggtat tttattacag atatttttta
    38161 aaaacccaat agttgaaccg tatatattag gagtatcttc aggttctact ttatcagtag
    38221 ctctcatgat tttgggagga tacacattgg gatttgagag tgtaaattca atgagtatat
    38281 ttgtagcagc ttttatagga gctttaattg taatgtctat agtcatttta tttgcaaata
    38341 aggtaaagaa tataacaact cttttaataa taggaattat gaccggatat gtatgtagtg
    38401 gtataacaaa tgtgttacaa tcatttgcaa atagtgataa attaaaagaa tttactatgt
    38461 ggtctatggg aagtttttct ggatttacat gggaaaaggt agaaatactt ataatagttg
    38521 gtatgttagg tcttttgatg actgtattca taataaaacc tttaaatgct tttttattag
    38581 gagaagagta tgcaaaaagt attggcgtaa atataagctt ttttagagtt ttgatagtat
    38641 ttatatctag tatattagca gcaatagtat cagcatttgc aggacctata gggtttattg
    38701 gacttgcagt gccacaaatt tcaaaattga ttaaaaaata gctacgcaca cttgtgactt
    38761 tagtcatgag ttagtagcta aaatagtcag catataggga aac
//
LOCUS       DACTZW010000033        38729 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.033, whole genome shotgun sequence.
ACCESSION   DACTZW010000033 DACTZW010000000
VERSION     DACTZW010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38729
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.033"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            124..1341
                     /locus_tag="JAM15_09025"
     CDS             124..1341
                     /locus_tag="JAM15_09025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017470872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HAT6798390.1"
                     /translation="MLIGLIAAFGLVLQKKKASDVIKGSLLAAFGIIIMETGTGMLVS
                     SIAPINGAFQSISGGAVTKGLSDVTFTASYGGIIGLAMFAGLAIHLMIARFTPIKTIF
                     LTGHMLYWFPFIFVASGVEAGLNGGVLIAFAAVLSALYWSIMPWLLRKYVFDVIGDDS
                     FTLGHPSGCLALISGFVAKLVGNKEKSTEDINIPQSLSFFREISISGGMAVFLMFIVV
                     GIVIPGAFKDSNEFIGTYAIKQGLSFGAGLIIMLHGVRMLINQIMPAFQGISEKVVPN
                     ALPAFDCPILFNYKPNAVLIGFLVAMLTSTAMILICNYFNVFNLLLIPLVITSFFECG
                     AAAVIGESQGGIRGAIIGTAIAAIFMVVLVGISAVIYSGTIQNWILIFGGNDLSLFGI
                     ISKFIGSLFGGIL"
     gene            1344..2084
                     /locus_tag="JAM15_09030"
     CDS             1344..2084
                     /locus_tag="JAM15_09030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAT6798391.1"
                     /translation="MKFKYIDEIRRLIDIIENEEKVNMEKAVQILVEAIESKNAIFSF
                     GASHAGILTEELFYRAGGCVLINPVFAKSLMLDTAPITHTSKMERLEGYGTALADKTP
                     IKKGDVVIVHSVSGRNPVSIEFAMKAKENKAIVICITNLSYSKSVSSRHSSGKKLYEV
                     CDLVIDNHGQKGDACVEIDGLNQKVSPTSTVIATTVMNSIIAQATQELVNKGLKNPPI
                     FYSANIDGGDELNKKIFDEYKSVIHYEY"
     gene            2407..3717
                     /locus_tag="JAM15_09035"
     CDS             2407..3717
                     /locus_tag="JAM15_09035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAT6798392.1"
                     /translation="MKKENKMEGIKVGMLKKLCSLAMVTIMTTTLITGCSSGNGKDSK
                     KDGEKEKLVLWMPPVENNMKEVWDPILDKFEEKNNCEVDLQIIPWDNYSEKFATAISA
                     GEGPDVGYMYAEMYPQFIESGAVEDLTNYATKEDKEQSIYIKTSEMMGGMYGMPFQAA
                     NPGVLYYNKDILEKLGEKPPKTWEDFKRICKKATQDTDGDGKIDQWGLAQGWGAKTFG
                     NLNWNWYPYLWQAGGDIFNDDLKSVKFNDKSGLEAANFLKELQAYVPEDSLSKDSNEM
                     IESVFGPGKAAFTIMLSSAATSVFDESFPDLNWGFVTGLEDKKAATFGAVDHLSLMSS
                     AKNKELAYKLIQHMLSVESMTEFHKAIPRAPITKGEPYQGDERFKEMVENDKNVYRPL
                     VVGPHGVEIYEYLWKELQTMISGDKTPKQALDDAAKYSNDLLAQ"
     gene            3815..4732
                     /locus_tag="JAM15_09040"
     CDS             3815..4732
                     /locus_tag="JAM15_09040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAT6798393.1"
                     /translation="MENLVREFEENSKRKKTKLNIKPYMYILPLGIILVAFYVIPIIM
                     SIYFSFTKYNIISPATFIGLENYKKLFTDETLKVSIINTIKFTVVVVPCQTILSLILA
                     VWITGKGNSKIASFAKGAIFIPVLSSMVLIGMVWRALLNGEGSIIYQVLGAFGIESSK
                     LLGDSKTALPTLMFISMWKNIGYFMVIYISAIMNLPKHCYEVAKVDGATKLQEFIKIT
                     VPLLKPTTIMVVFLGSIWSLQVFDLIYTVTGGGPGISTMSIVMHAFNLNFKNFNSGYA
                     MTVANVLFLLIAVVSILQNKLVKRDNSDF"
     gene            4748..5557
                     /locus_tag="JAM15_09045"
     CDS             4748..5557
                     /locus_tag="JAM15_09045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAT6798394.1"
                     /translation="MKTARRLLSDGLLLFIACASLVPFIYMLIISLKITYNSYSLDIS
                     FSTVTLQNYIDIFTKKGFAQYFFNTAIVSFSGVLLNLVFSTLAGYSFAKMDFKGSDKL
                     FLFMIMTLIIPSQVTMIPLYIIMKHLGWINSYLALIMPIPTAFGVFIMRQAILGVPKE
                     LLESAKIDGCSDFRILIQIVLPLIKPALITLAIFTFMGAWNEFMWPLIATTKDAMRTL
                     TVGLSTLKTFQITNYGQMMAGATITFLPPFIFYLILQSKFVEGVSLSGIKG"
     gene            5615..7363
                     /locus_tag="JAM15_09050"
     CDS             5615..7363
                     /locus_tag="JAM15_09050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4091 domain-containing protein"
                     /protein_id="HAT6798395.1"
                     /translation="MEISYVLKDCTFKHNKYSVIEAETWKDKDLDIVVAKGEKFAFQI
                     MLKATEEFNCTIDKSSTISWKGLGNRVRLALNVPNSLENNFSINILGYVQDDTKAFVN
                     DAILRDKDVLVEQYLPQTFWIEGQVPEDFEENNLDIGIDIFKSFGYEDEEKVCTIDVP
                     VKVRNVVLKPLDESKFFLDLWQHPSCLARMYKVELWSDIHFEIVDNYLKELASLGEKV
                     ATVIVSDYPWAGQSCYKVYKNPSNLYEYNMVSVSKGLDGKIKCNFESMDRYISIADKY
                     KMAQEIDLFGLLGNWCAGEFGNPVEGYKDPIRVRYFDENDKVFKFINNTNDLKEYIGL
                     VLNHLIECGLWDRVRIIADEPNNPEVVKECIEFINSTVGTRQVKYKSATHDQNFLDRA
                     KDEIDDMSINLKLTIQNYKDIENLKKKINDKGGILTWFVCCFPEKPNSFLSSPFVENR
                     IIGWYTYYFGLDGFLRWDYNLWTEDPWKDSSYKFPIWKAGDMFFVYPGKDLKPVRSVR
                     MENLRFGIQDFELFTMLEKEKGREYIEVELMQELLNKKENAEIKGFGDIELGYSLDNW
                     GYDKVKKYVLELLDRV"
     gene            7625..8647
                     /locus_tag="JAM15_09055"
     CDS             7625..8647
                     /locus_tag="JAM15_09055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 5 protein"
                     /protein_id="HAT6798396.1"
                     /translation="MFGGINIKRIGIIIMFFLSIAFIGFYLAIRGNSDTVKMQRGINI
                     GNALESPKDFPWDVKMSNKFFDDIKDAGFDTVRIPVRFSDYTSDSDNFKIDEEFFKKI
                     DKYVDYALDKDLIVVLDLHHFEEIMKEPRVHKEEFLKIWQQIANRYQKYDKKLVFELL
                     NEPKENLSSQLLNEYIEEAIKIIRKTNPKRTIIVGPYNFYQIDYLNELNVPKDSNIVV
                     SFHYYEPNDFAFQGNIYHNGFEHLSNITWEGTNEQMDYLKKRFDIVENWANKNKVKIF
                     LGEFGVTKEAPEASRRAWIKAVREEAEKRNFSWAYWELASGFGIYNQIEGTWDRDILS
                     ALIEKR"
     gene            8652..10958
                     /locus_tag="JAM15_09060"
     CDS             8652..10958
                     /locus_tag="JAM15_09060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAT6798397.1"
                     /translation="MKKNSKKILITLTIITNIVYILWRIFYTVPKEEGMFALICAIIL
                     LFVEIMGMMEMFVHYYGMSNIEYPEKPVISEELYPHVDVFIATYNESVDLVRKTVNGC
                     IHMQYPDKKKVHIYICDDGNREEMRILAEKMGVNYITRTEREGAKAGNLNNAMQHTNS
                     PLIATFDADMIPMHDFLIATVPYFLKNEQAKKDGEKEEYEKVGFVQTPQSFYNPDLFQ
                     FNLHSEGRIPNEQDYFYRDIQLARNRTNSVIYGGSNTVISREALEEVDGFYTYSITED
                     FATGILIQSKGYRCYAIPEVHASGLSPTDLKSLIKQRERWARGCIQTGRRLNILFRRG
                     LGFWQKISYISSITYWYASIKRFVYIMAPILFSVFNVIVVKCTLLQVLVFWLPMYILS
                     SLSLKIFSQNIRNTRWTNIYETIMFQSLMPAVILETFAISKNKFSVTNKNKLEENRMY
                     KFLQGIPYFIYMVLSIIGILKMFVAIFKMSSMTYSVVLFWLIGNLFNLVMATLFISGR
                     QQLRKSERYIAEIDFKLKQNSYVLSSKTIDISENGFAFLLENPEYISPEEEFEVEFRE
                     KSGNEMYIANMKAKIVNVVEVNSKWKYAAYITHIEDSEIDNWMCIVHDRIPTLPMTIS
                     NQLGFFDDLQINVKKRIEKIRTLSRRSPRINMNFQMDIKNTGKLRIVNFNYQYVLLNF
                     ENKNIYPKEIALEINENIVLECDLCEGKIDERGILYKVNNIDSIMQNFFLRDEMMDWI
                     LQNKTIPVSNPSEKKEKSIDEFEPMEYI"
     gene            10930..12045
                     /locus_tag="JAM15_09065"
     CDS             10930..12045
                     /locus_tag="JAM15_09065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798398.1"
                     /translation="MSLNPWNIFRRDEMKTLKVFFCSAKYLILVFIFFINTTFISSAT
                     SDKILDLSFKKIETDLSSRITYEDTGVKIETDSSKSDKERYLYIYQNIKENWSMYNNF
                     YIEIQNKNKSSQKINLSIQSKNMLEFRLKEGSEIFLEDKNIIYSDKIKEGCIEVPGEF
                     EGKIYVNFNSLINEKSNVVLDSSMLSNIVSWGITFIPSDEEHNIVIIKKISLLSEEKL
                     SFLHNIKITGNEEVQIPVLGQSISQYEVLGLKRDSKIKYSLMGKQDNVSISQNGKLTL
                     SNKAEPGQIILQVNVDDKFKIGRKIALTESWSINKKDKDGVPYTLVSPEQSPTVQDMK
                     KINFMNNIITFVRILFVSLVIICFGIYLYWKKCSKTK"
     gene            12063..13481
                     /locus_tag="JAM15_09070"
     CDS             12063..13481
                     /locus_tag="JAM15_09070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBOAT family protein"
                     /protein_id="HAT6798399.1"
                     /translation="MLFSSLIFLFYFLPITLVLYYVFRFNRTIQNMILLAVSLFFYAW
                     GEPKFVVIMIVSIIMNYIFGLLVDRYRESKIKVKVFLVLMCVYNIGVLFIFKYLAFAL
                     RNISELINTELTIPSIVLPIGISFFTFQGMSYVIDVYRRHGEVQKNPFYVGLYIAFFP
                     QLIAGPIVRYESVAEQILNRKETWNKFSIGTCRFITGLGKKVLISNNMAIVADYIYTM
                     NSQGEIAASLAWLGSIAYTMQIFFDFSAYSDMAIGLGLMFGFKFEENFNYPYISKSIS
                     EFWRRWHISLGMWFKSYIYFPLGGSRVANKDIMIRNMFIVWLFTGIWHGAEWTFVIWG
                     ILNFVFLIIERFIMFEKIENHNFIKHIYALLVVNFGWVLFRSPNLKEAYNYFKAMLGG
                     NGVIWSDYTYMFLKEYWVFFIFAFIFSVPIAKKINKFVVEQAKYSMIFNVFYPISAIL
                     LFFISVTYLVTGSYNPFIYFNF"
     gene            13496..14704
                     /locus_tag="JAM15_09075"
     CDS             13496..14704
                     /locus_tag="JAM15_09075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798400.1"
                     /translation="MNRFFKVRLITAIMFLIILFAFSIFNICYSGKDMIQEIKNSVAE
                     KSSLKDTISSIDNTVNDKVIYKNTFIETYGYLQKLMGKNEFSKFSVVKDTSGKMHYTY
                     FAKAPNPVGVIADRVRKFSEEMEKQNTKLVYLMTPDKYIKGVTKFPKGIPYSYSNETA
                     DNFLNQLKKYNVDYIDFRENILKSGIPKDDLFFKTDHHWKVETSFWAFGELVEQLNKK
                     YNMNLDENHYYRDKENYNSIVYPKSFLGSMGRKTGILYGGIDDFTLIYPKFKTNYTYY
                     TDSKSQKFELKGRFEESLILSYPFNADLDLMDGQSDKYFTYLLGNRPLVKIKNIENPD
                     GLKVLFVKDSLIVPTAAFFSSVCSSIDMIDPRYYDGDILEYAKSHDYDFVFISVYPQN
                     LTKEFFPFCK"
     gene            complement(14785..16173)
                     /locus_tag="JAM15_09080"
     CDS             complement(14785..16173)
                     /locus_tag="JAM15_09080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:dicarboxylase symporter family
                     transporter"
                     /protein_id="HAT6798401.1"
                     /translation="MESSFLSQFLMITDFKTIFFIILLLGTFFIVRQFEKKKIKFSLR
                     TIYATVLGLILGIIIQAFAGFPNDTTQVTWLQEVSKWYSLFGSGFMDLLKMLVVPLVF
                     LSIIKVIINMKDNNLGTLTFKSLGMLLATTAIAAIVGIIVANIMKLGVGANMPTLVEN
                     QELKEINSLVDTLRGLLPSNPVMAMANGNIVATIIFATFIATSIKRLSKKYFETIKPF
                     IDFIEASYKIIVSVSMTVIKFMPYAVVALLANTITSQGISSIVSVLQFILALYISVAI
                     LFTIHLIFITLNGLNPITYIRNSTEALLLAFTSRSSLGTLPVTIESLVQNHGVDEGVS
                     SFTASLGANMGMNGCAGIYPALMAVTLANMAGVNMDMSFYVMLLIVITISSFGIAGLP
                     GTATMAVSVVISGVGLGSYFPLVGGILAIDPILDMGRTMINVNGAMVSSITVGKSLGK
                     IDKEVFGKKNIS"
     gene            16515..17849
                     /locus_tag="JAM15_09085"
     CDS             16515..17849
                     /locus_tag="JAM15_09085"
                     /EC_number="1.8.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017826042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HAT6798402.1"
                     /translation="MRVVIIGGVAAGMSAAAKLKRIKPEYEVVVYEKTEIVSFGACGL
                     PYFVGGFFDDADELLARTPEKLREAGIDLNIFREVVEVDSESKKIKVKNIKTDEIYED
                     YYDKLMIATGARSIMPPIKNIKLKNVSTLKSLYDGEYLKKLLSNEDNKRVTIIGAGFI
                     GLEAVEACKKLGKDVDVIQLEDRILPQVFDKEMTDVLEEEINRHNVNLHLDEMVVELC
                     GEDKVEKVITNKGEIDTDVVIIATGVRPNTEFLSNTNIKMLKNGAIVVDEYGRTSVED
                     IYSAGDCATIKNIVSNENVYVPLATGANKLGRIVGENLAGREVSYQGSLSSSCIKIMD
                     MEAASTGITEKQAKDLGINVKSKFISDYNQTHYYPGRNKIYVKLIYDADTKVILGGQV
                     AGFKDAVQRANVLAAAIFGKMTTSQLGMLDLCYAPPFARTWDVLNVAGNVSK"
     gene            complement(17978..18895)
                     /locus_tag="JAM15_09090"
     CDS             complement(17978..18895)
                     /locus_tag="JAM15_09090"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HAT6798403.1"
                     /translation="MIDLTLLGCGGNVPMPNRFLSSVFINYKGRKILIDCGEGTQVSM
                     KLKKCGFKDIDLICITHLHGDHIFGLLGLLSTIGNSGRTSDLTIVGPVGIVDCIRSMR
                     NLVEYVPYTLKIIENPQGNFSLDNKVLRNLEISTISLEHSIECLGYSFNFRRNPKFDI
                     DKATKNEVPKILWNKLQEGQNIVLNSKQYTPDMVLGELRKGVKISLTTDTRPIESIPD
                     FIKDSDLFICEAMYGDDLDISKAVRNKHMTFREAANLAKLGNVKQLLLTHFSPSLDIP
                     SMYLENATNVFENTILGEDRLSLRLNFDE"
     gene            19103..19987
                     /locus_tag="JAM15_09095"
     CDS             19103..19987
                     /locus_tag="JAM15_09095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4846 domain-containing protein"
                     /protein_id="HAT6798404.1"
                     /translation="MKVLKKITILSLITLTLVGCSNGEDKKVVEGSKKIQNSKKDEQP
                     IIVHKDANILKDRYEPPKGFKRVDVEKGSFESFLRNTKLKNYGEKVKYYDGRIKESKG
                     IYDSVFDVDIGNRDLHQCADAIMLMRAEYLYQNKLYDEISFDFVDGFKAKYSKWAQGY
                     RISVKDSGSSWYKATEYSTSYESFRKFMDIVFAYSGTLSLEKELEPVKVEDMKIGDVF
                     IVGGSPGHASIIMDMAENEKTGKKVFMIAQSYMPAQQTQLLINRKNPNLSPWYSLDFE
                     GDLTIPQWTFKRDQLKRF"
     gene            20200..22041
                     /locus_tag="JAM15_09100"
     CDS             20200..22041
                     /locus_tag="JAM15_09100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HAT6798405.1"
                     /translation="MKIRRYLILVIIILITTSQSFISYGLERFEEITIFHTNDIHGRY
                     AEGDDHIQIGNLATLKKETPNSILVDAGDCLHGLPIVNMDRGKSAIELIKCAGYDYIT
                     PGNHDFNYGKDRLFELSKSANLGENTLKFLSSNIFENGKKVFDSNDIKEIDGIKIGFF
                     GLSTQETKNKTGFKNVEGLEFKNPIESATEQVNELKGKGANVIVAICHIGTSSLSKPN
                     SIDIANEVQGIDLIIDGHSHTKFENGKQVGDTLIVSAGQYLENIGEIKLTLDTNDVEN
                     IKIENKSVRLIGKEEALKYKLDYVVSKKVNEIKEQQEKILDKVIGATTNTLDGSYENV
                     RTKETNLGNLISDILLDKTKADISLFNGGNIRDTIEKGNITRRDIVDVFPFSNTIVTK
                     ELTGAQIKDVLEHGVKLYPEKSSAFLQVGGISYYFNPKQKEGERITSIQKEGKPLDLN
                     KKYVVATNDYIASGGDEFPCFSKEPILKEFGNLESAVIEYIEYKKEISKNVDGRIGIK
                     SKDELISKNHESDLILSENEKNINDNEENLSNNIKSSDSDKNKSLDKTSARESSNLGI
                     SKREAKEKSPKTGDLGFSNSIIIFIVSSTLICLLNFNQKELKDKKSK"
     gene            22324..23052
                     /locus_tag="JAM15_09105"
     CDS             22324..23052
                     /locus_tag="JAM15_09105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6798406.1"
                     /translation="MMMEDIGMNNILLLEDDKSLNRGISFKLKKEGYNVFSAFGIEEA
                     KNIFAKEEICLIISDIGLPDGSGFDFCEEIRKKSDVYIIMLTALDEEVDIVTGYDLGA
                     DDYITKPFSLMVLISKVNALMKRVNTVKNYTLLVCDDLFFYYIENKLIIRTDDKEEEI
                     ILSKTETKLLKYLMENSMQTLTKEQLLESLWDSSGNFVDDNTIAVNIRRLRQKVEKNP
                     SEPKYIKTVRGVGYMWGERSIKKC"
     gene            23046..24356
                     /locus_tag="JAM15_09110"
     CDS             23046..24356
                     /locus_tag="JAM15_09110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAT6798407.1"
                     /translation="MLKNMNLKDGLSVKDDYIMRRVIVYSVLSVLIVTLVFILFEYSR
                     LHKLYEHQIKNTQNIAGILIEKYPNDEIDIVNSIYNSDYSKVSTGEKAFKKFGYGLEN
                     KMSNDKNFSLYLKSFFKESFFIFLMMFIVVIGIIYYFIRYINKRLSKIYFIVDKMAQE
                     NYLKDTTESEETGYLVEYNEYFKEGTFSKINNCLYELNRSLKIKFIKLEKEKESVKSL
                     VTDISHQLKTPLASLKLYNTLLIEEELEEDEANEFLLTNKASINKLENLINSLVNISR
                     LEISMINIKKEDNDIKNTILNAVKSVTPKAKSKSITLNLNEFNSRIIPHDKKWTEESI
                     FNVLDNAVKYTQVNGEINISVEETANFFKIIIEDNGIGIEKNEFNNIFKRFYRGSADE
                     IESVEGSGVGLYLSRKILEEQGGNIIVSSKVGIGSKFSLFLTTM"
     gene            24473..25156
                     /locus_tag="JAM15_09115"
     CDS             24473..25156
                     /locus_tag="JAM15_09115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6798408.1"
                     /translation="MKILYTENLSKHYGKGENLVRALDNVNLEINEGEFVAIIGKSGS
                     GKSTLLHMIGGLDIPTSGKVYIDNKNIFTLKEEELAVFRRRKIGFIFQSYNLIPSLNV
                     WENVVLPIGLDGREVDESFIKELLKSLGLENKHDVLPNTLSGGQQQRVAIARALATRP
                     AIILADEPTGNLDSKTSDEVMSILKSMSKKYSQTLVMITHDDSIAQMADRVIFIEDGR
                     VSKVGDKND"
     gene            25149..27536
                     /locus_tag="JAM15_09120"
     CDS             25149..27536
                     /locus_tag="JAM15_09120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAT6798409.1"
                     /translation="MINTTKIAKSNLKQNKSKSILIIITIILSTLMLSSIGIYIVDAG
                     AYQKENTIKYSGNYQGILANVDEKQADILSNHADVELTGEMNGVGVEKLEDDSNISLA
                     YMNEDALKLNSFELIKGKLPTKENEIVLDSGALKALGYKNKDLGEKIKISYNDYKNDK
                     KIEKEFVISGILKTSEISEAGKYYYAIISELYMRNTRDMSQEDFNIYVKFNDKSNLSI
                     EQAKEKLDKIANDIGLDTINTAVNENYINALKPDMETIMGGGFVGLVIVLSSILVIYN
                     IFYISIVTKVQEFGKLRAIGATKKQIKNIVFKEGFILAGIAIPIGIILGYVLANIIIK
                     SFMDIDVKSSRLPVILSVVVISFISVVLSLLKPMKVASKVSIVDAVRYTGNKISNKSK
                     RKGYKNINLKRLSHANLERNKKRTYMTLASLILSGTIFITVSTALESFDAEKMAREHF
                     PYDIEVRLSGYEMNSDKNPKNNLNILQMDNPLSKDFFNQIKNMEGIKRIESARSVKIG
                     MEDYDVEFKYDLLQSINENDVKSLNKNLIDGKINLERLQTGDEIVITHVDTAKEMGVK
                     AGDKIRLTLYDGDKKIKKEFKVQAIAMGVPSFGIGKDFIDRTLKYDSTSSLGIYTEEG
                     KYQEIKDSIKKIAKNNGFLETDFIDSRIESNKAVISFIKIMGYTLTGIIGVIGFMNLV
                     NTMITSIVTRKKELGMLQAIGLTNKQLVKMLNSEAMYYTSGMMIGSILFGGILGYIAV
                     IFLKKTGLSYATYSLPIVPILLMIVCILIAQFITTYLIGRSFNKESLIDRVRYSE"
     gene            27815..28957
                     /locus_tag="JAM15_09125"
     CDS             27815..28957
                     /locus_tag="JAM15_09125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HAT6798410.1"
                     /translation="MNKKINYAPGPTETRENVRLARAEKTTNPDIDIDFVEFYKKTCE
                     KFGNIVGTKNDVYILSGEGILGLEAACASLTEKGDRVLVIDNGIYGEGFKDFVTMYGG
                     EYVLFSSEYTKSIDIDELKAFLDEDSNFKYATVVHCDTPTGVLNDVSKICPLLKEYGI
                     LTVVDSVAGMVGERLSVDESKIDIILGGSQKAISAPAGLTIVGISQDAKNCIKNRKTD
                     VIGFYCNLNIWEGYYEKKYFPYTMPISDIMGLDKALDNILEEGIENVLDRHEKIAYSV
                     RKSIEEYGLELFLEEGYSNTVTAIKIPESIGALKLTDYMLKNYNTLVATSLNQYMDTI
                     LRIGHMGENANLNKIEHVLNVLDKSLSALGFKGNENLLNLFNKYYF"
     gene            28976..29500
                     /locus_tag="JAM15_09130"
     CDS             28976..29500
                     /locus_tag="JAM15_09130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAT6798411.1"
                     /translation="MEVTAKQKFTTKDMVETSLLIALVFIATKFINIRLPISINGGLV
                     HLGTAMLFISAIVFGSKKGALSGAIGMSLFDLISGWTLWAPFTFIVRGVMGYLLGKIA
                     WANGNNGNNFLINVIGICVSSIWMLFGYYITEVILYGNFIVPLTSIPGNLMQVLIGLI
                     IALPISKVLKKCIK"
     gene            29600..30418
                     /locus_tag="JAM15_09135"
     CDS             29600..30418
                     /locus_tag="JAM15_09135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAT6798412.1"
                     /translation="MLSVTRYSIKNVRLKPWVKFIWYFETKSNILLNNKLLPTDSIDI
                     ILNLSDVMEYKIENQDYTASNMHFNGIRDKHGFIIQHGNIRVIGISFYPFGLYPFLKI
                     PISEFNRQIVDLEAVSELFAKKLEESLNPTQSVEKIVLYLEEMLLSILEEDLISNKSV
                     KLLNSFIYDNRYSNIKAFCDNTNINIKTLERICLKYTGYTPKILKRIYRFKMASNQLI
                     YNYKDNELFDFIYENEYYDQAHFIKEFKKFSGTSPIKFIGENKTIKENIKYSYL"
     gene            30496..30807
                     /locus_tag="JAM15_09140"
     CDS             30496..30807
                     /locus_tag="JAM15_09140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798413.1"
                     /translation="MKIITEIVEFNVEENLSKEEFIEIVNDLELKFHSIQSGFIDTEL
                     LYDEKSQKWIMIQHWKSMEKLKSASSKMFKDSSTEKFRKALKNQTVKMNIIPQIKSWK
                     L"
     gene            complement(31110..33113)
                     /locus_tag="JAM15_09145"
     CDS             complement(31110..33113)
                     /locus_tag="JAM15_09145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan-branching enzyme"
                     /protein_id="HAT6798414.1"
                     /translation="MKSQKRFKILDIDVYLQPFESDIKKRMKHYEDMKSKILKNYKDF
                     SSFANAHLYYGFHQTNDGFFYREWAPNADSLSLIGDFNNWNRKSHPLRKIGAGNWEIF
                     IPGQNSLPHKSEVKVQVTANGKTFDRIPLYIKRVIQKDFGGFNGQIWQPKTPFIWTDN
                     DFDLKNITSPLIYECHIGMSTESESIGTYNEFTEKILPKIKKAGYNTIQLMAIMEHPY
                     YASFGYQVSNFYAISSRFGTPEDLKNLINTAHSMGIAVLLDLVHSHAVKNTLEGINEF
                     DGSEHQFFHSGSKGNHPAWGTKLFNYGKPEVIHFLLSNIKFWLNEYHFDGFRFDGVTS
                     MLYHNHGLGVSFDSYEKYFSMNTDIEAITYLQFANELIKEIKPNSISIAEDMSGMPGM
                     CIPIKDGGIGFDYRLAMGVPDFWIKTISNLSDEDWDLGKMWYELTTRRPGEKNIGYCE
                     SHDQALVGDKTIIFWLADKEMYWNMEINSNNHVINRAISLIKLIKLITFSLAGEGYLN
                     FMGNEFGHPEWIDFPREGNNWSYKYARRQWSLSEDNNLKYKQLLSFDKSMLELTKYSD
                     IFIQNSHELIHMDNDKKILVYSKGKYLFIFNFHPNLIQSVDISKFQNTNYKTILNTDM
                     VEFGGNTKKENLRDYDVYFSSTPPSSKMPIASRTAIVLLDNGI"
     gene            complement(33266..33904)
                     /gene="recX"
                     /locus_tag="JAM15_09150"
     CDS             complement(33266..33904)
                     /gene="recX"
                     /locus_tag="JAM15_09150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HAT6798415.1"
                     /translation="MGIITKIEQQKRNDDRVNIYVDDKFFIAIFKELVYTFNLKKGNE
                     INEEELKPILDDEMYIKAKNKALNILSHADQSEKKLKEKLSSEFDENIIERVIDFLKS
                     YNLVNDSVLAQKIVNTNVNLNKCGKNRIKQNLYNKGINRSTIDEAVSELDKDTEFENA
                     MYLAKKRYERVKKEDKKKIYQKISQHLSYKGFDYDIIKRVLNKLLNFDEYDI"
     gene            34180..34869
                     /locus_tag="JAM15_09155"
     CDS             34180..34869
                     /locus_tag="JAM15_09155"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HAT6798416.1"
                     /translation="MRSENLVKMAELKNTEKLEKFNRHKGKIKIGILGGTFDPIHYAH
                     LATAEFIRDKYDIDKIIFIPSGNPPHKLCITTDKYDRYNMTLLATESNEDFLVSKVEI
                     ERKKRTYTIDTLKYLKKKYKNADIYFITGADAICSVEEWKDVKKNFELATFIAATRPG
                     ISLLRSQETIEKLTKKYNADIITVYVPSLDISSTYIREQLNEGKSIRYLVPENVENYL
                     YENKLYQYGDD"
     gene            34870..35442
                     /locus_tag="JAM15_09160"
     CDS             34870..35442
                     /locus_tag="JAM15_09160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAT6798417.1"
                     /translation="MNLENINQRLNQMLPVGRLSHSKNVAKCAEKLCEIYGCDKEKAY
                     LAGMIHDCAKYLSDKEIEDYVNKYEIYLDPIEDGNRSLSHSVIGAYICEYEFEVEDED
                     IINAIKYHTTGREDMSLLEKIIYIADLIEEGRKFPVVDTLRELAYGGKLDEALLTSFN
                     NTLMFVINKKEEIHPRTVMARNYLIKEKLL"
     gene            35559..35909
                     /gene="rsfS"
                     /locus_tag="JAM15_09165"
     CDS             35559..35909
                     /gene="rsfS"
                     /locus_tag="JAM15_09165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HAT6798418.1"
                     /translation="MTVEQMTKIAYDAIEDKLGQDTVIINIGKVSSLCDYFIITTASS
                     QRQVKAIADNVEDELAKLGLEPRGKEGQGTQTWVLLDYGDIMVHVFNEENRGFYNLEK
                     LWKDAPYIDIDTLA"
     gene            36263..38683
                     /locus_tag="JAM15_09170"
     CDS             36263..38683
                     /locus_tag="JAM15_09170"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002844582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HAT6798419.1"
                     /translation="MSVYNFKEVESKWQKIWKDNNQYKMDTAQTEKPNYYTLEMFPYP
                     SGKIHMGHVRNYSIGDVVARFKKMEGYNVLHPMGWDSFGLPAENAAIKHGIHPHKWTM
                     ENIEEMKEQLNLLGISYDWDKEVATSTPEYYRFTQEIFLKFLEHGLAYKKKSYVNWCP
                     SCETVLANEQVVQGACERCKATVLKKDLEQWYFKTTEFAEELLNDLDTLDGWPEKVKT
                     MQKNWIGKSTGADLVFDIDGTDKSMTVFTTRPDTTYGVTYMVLAPEHELVKELVAGTE
                     YEADVEAFVQKMHTMTEIERTAADVEKEGMFIGRYVINPLNGKKVPLWIANYVLVEYG
                     TGAIMAVPAHDERDRDFAEKYNLDIIDVITEDNKMINSEEFNGLDASEGFEGIIDKLE
                     KEGRGKRTINYRLRDWLVSRQRYWGCPIPVVYCDECGIVPVKKEDLPVLLPTDVEFTG
                     KGESPLTTSKQFMSTTCPHCGKPARREVDTMDTFVDSSWYFLRYVDSNNENEPFSKEL
                     VNRWHPVDQYIGGVEHAIMHLLYARWFVKAFKSMGMVDFNEPFKNLLTQGMVLMDGSK
                     MSKSKGNTVSPMDIIDEYGADTARLFVLFAAPPERDLDWSEQGVDGCFRFLNRVYRLV
                     DELADVVKKDVEFGELNSQDKDMRYTIHSTLKKVTADLSEKFGFNTAISALMELINDM
                     YKYKELDNINEAVIKEGVQTIVTIIAPFAPHLGEELWTMIGKEGSVFDIDWPKYDEKA
                     LVKDEIEVVVQVNGKVRGKLTVNSNISKDEMEKVALEDEKIKGLVEGKTIVKVVAVPK
                     KLVNIVVK"
BASE COUNT        14997 a         4206 c         6703 g        12823 t
ORIGIN      
        1 ggatagcctg tggagaatta gtaggacata ttttagtatg caaaattcta tgaagcagga
       61 accctgtgac tttagtcatg ggaggttcag tttatttcaa ataatatttt acgtaatcca
      121 tctatgttaa ttggattaat agcagcattt ggtcttgtac tacagaagaa gaaagcatct
      181 gatgttataa aggggtcact acttgcagct ttcggaatta taattatgga gactggaaca
      241 ggtatgttag ttagttcaat agcaccaatt aatggagctt tccaaagtat aagtggtggt
      301 gcagtaacaa aaggtttaag tgatgttact tttactgcaa gttatggtgg aattataggt
      361 ttagcaatgt ttgcgggttt agctattcac ctaatgatag caagatttac tcctattaag
      421 acaatcttct taacaggtca catgctttat tggttcccat tcatatttgt agcttcagga
      481 gttgaagctg gattaaatgg tggagtatta atagcttttg cagcagtatt atcagcactc
      541 tattggtcaa taatgccttg gttattaaga aaatatgtgt ttgatgttat aggagatgat
      601 tcttttacat taggtcatcc atctggttgt ttagcactta tatcaggatt tgttgctaaa
      661 ttagtaggaa ataaagaaaa atctacagaa gatataaaca tacctcaaag tttatcattt
      721 tttagagaaa tatctataag tggtggaatg gcagtgtttt taatgtttat agttgttggg
      781 atagtaatac caggtgcgtt taaagatagt aatgagttta ttggaacgta tgcaataaag
      841 caaggtcttt cttttggagc aggtcttata ataatgcttc atggggtaag aatgctaata
      901 aatcaaataa tgccagcatt tcaaggtata tctgaaaaag ttgtgccaaa tgcactacct
      961 gcttttgact gtccaatatt atttaattat aaaccaaatg ctgtattaat aggattctta
     1021 gttgctatgc taacatctac agctatgatt ttaatatgta actactttaa tgtatttaat
     1081 ttgctactta taccacttgt tataacttca ttctttgagt gtggagcagc agcagtaata
     1141 ggagaatcac aaggtggtat acgtggagct ataataggta cagctatagc tgcaatattt
     1201 atggtagttt tagtaggaat atctgctgta atttactcag gaactattca aaattggata
     1261 ctaatatttg gaggtaacga cctttcatta tttggtataa ttagtaagtt tataggttca
     1321 ttatttggag gaatattata gatatgaaat ttaaatacat agatgagata agaagattaa
     1381 ttgatataat agaaaacgaa gaaaaagtca atatggaaaa agcagtacaa atccttgttg
     1441 aagcaataga aagtaaaaat gctatatttt catttggagc ttcacatgca ggaatattaa
     1501 cagaagaatt attctataga gcaggtggct gtgttcttat aaatccagta tttgcaaaat
     1561 ctctaatgtt agatacagcg cctataactc acacaagtaa gatggaaaga ttagaaggat
     1621 atggtacagc tctagctgat aaaactccaa ttaaaaaagg agatgtagtt atagttcatt
     1681 cagtatctgg tagaaatcca gtaagtatag agtttgctat gaaagctaag gaaaataagg
     1741 caatagtaat atgtataact aatttaagtt actcaaaaag tgtatcttca agacattctt
     1801 caggaaaaaa actttatgaa gtatgcgatt tagtgataga taatcatggt caaaagggag
     1861 atgcctgtgt agagatagat ggattaaacc aaaaagttag tccaacttct actgtaatag
     1921 caactactgt gatgaactct attatagctc aagctactca ggaattagtt aataaagggc
     1981 taaagaatcc tccgattttt tatagtgcca atattgatgg tggagatgag ttaaataaga
     2041 agatttttga tgagtataaa agtgtaattc attatgaata ttaaggttaa aaaaatatgt
     2101 taatgaactt tgaagtttat caacaaagaa tattaataat atataataaa tgctatcatt
     2161 taaaagctgt aggtaaaaat ctacagcttt ttattattgt agattaaaaa gatgcgtaat
     2221 taaattttaa attggagaaa ataaattgga aggtatcaat tataaatatt agaaacgttg
     2281 tcatagaaaa aaactatatt aaaaaaaagt acatagaaaa aactgattag acaataaata
     2341 catgctttga taatatttta aatggagtga aaatgtgtag aattataatg aaaaaagaaa
     2401 ataaaaatga aaaaagaaaa taaaatggag ggaataaaag tgggtatgtt aaaaaaatta
     2461 tgttcactag ctatggtaac aattatgact acaacactta taacagggtg ttcaagtgga
     2521 aatggaaaag attcaaaaaa ggatggcgaa aaagaaaaac tagttctttg gatgccacca
     2581 gtagaaaata atatgaagga agtttgggac cctattttag ataaatttga ggaaaaaaat
     2641 aactgtgaag tagatttaca gataattcct tgggataatt attctgaaaa atttgcaaca
     2701 gctataagtg ctggcgaagg tccagatgta ggatatatgt atgcagaaat gtatccacag
     2761 tttatagaaa gtggagcagt agaagatttg actaactatg caactaaaga ggataaagag
     2821 caatctattt atataaaaac atctgaaatg atgggtggaa tgtatggtat gccattccaa
     2881 gcagcaaatc caggggtatt atactataac aaggatattt tagagaaatt aggagaaaaa
     2941 cctcctaaga catgggaaga ttttaaaaga atttgtaaaa aagcaacaca agatactgat
     3001 ggtgatggaa agatagacca atggggatta gctcagggat ggggagctaa aacttttggt
     3061 aacttaaact ggaactggta tccttattta tggcaagctg gtggagatat ttttaatgat
     3121 gatttaaaat cggttaaatt taatgataag agtggtttag aagcagctaa tttcttaaaa
     3181 gaattacaag catatgtgcc tgaagattct ttatctaaag atagtaatga aatgatagaa
     3241 agcgtatttg gaccagggaa agcagcattt acaataatgt tatcttctgc tgcaacaagt
     3301 gtatttgatg aatcattccc ggatttaaat tgggggtttg taactggact agaagataag
     3361 aaagcagcaa cttttggagc agtagaccat ttatctttaa tgtcatctgc taaaaataaa
     3421 gaacttgcat acaagttaat acaacatatg ttaagtgttg aatcaatgac agaatttcat
     3481 aaagcaatac caagagcacc aataacaaaa ggtgaaccat atcaaggtga tgaaagattc
     3541 aaagaaatgg tggaaaatga caaaaatgta tatagaccat tagtagtagg acctcatgga
     3601 gttgaaatat atgaatattt atggaaagaa cttcaaacta tgatttcagg agataaaact
     3661 ccaaaacaag cattagatga tgctgcaaaa tattcaaatg atttattagc acaataaaag
     3721 tttaaagctg taatatgttg taaaggactt tacagattaa aattagcatt gtatttataa
     3781 atacaatgct aatatttata ttggagagga taaaatggaa aacttagtta gagagtttga
     3841 agaaaattca aaaagaaaaa aaacaaaatt aaatattaaa ccatatatgt atatattgcc
     3901 attgggaata attttagtgg cgttttatgt gataccaata ataatgtcaa tatactttag
     3961 ttttacaaag tataatatta ttagtccagc cacttttata ggtttagaaa attataaaaa
     4021 attatttaca gatgaaacat taaaagtatc tattataaat actattaaat ttactgttgt
     4081 tgtagtacct tgccaaacta tattatcatt gattttggca gtttggatta caggaaaagg
     4141 aaatagtaaa atagcttcat ttgctaaagg tgctatattt ataccagtat tatcatctat
     4201 ggttttgata ggtatggtat ggagggcttt attgaatgga gaaggttcta ttatatatca
     4261 ggtattaggt gcctttggaa tagaatcatc taaactttta ggagatagta agacagcatt
     4321 acctacactt atgtttatat ctatgtggaa aaatataggg tatttcatgg taatttatat
     4381 ttcagctata atgaatttac caaaacactg ctatgaagta gcgaaggttg atggggctac
     4441 aaaacttcaa gaatttataa aaataactgt acctttattg aaaccaacta caataatggt
     4501 tgtattttta gggtcgatat ggtcattaca agtatttgac ttaatttata ctgtgacagg
     4561 tggaggtcca ggtatatcta ctatgagtat agttatgcat gcatttaact taaactttaa
     4621 aaactttaat tctggatatg caatgactgt agcaaacgta ttatttttgt taatagcagt
     4681 agtttcgatt ttacaaaata agcttgtaaa acgagacaat tcagattttt agaaaggtag
     4741 gtataatatg aaaacagcaa gaagattatt aagtgatggt ttacttttat ttatagcgtg
     4801 tgcaagtttg gtacctttta tatacatgtt gataatatca ttgaagataa catataactc
     4861 atatagtttg gatatatctt tttcaacagt aactcttcaa aactatatag atatctttac
     4921 taaaaaagga tttgcacaat atttttttaa tacagcaata gtatcttttt caggtgtatt
     4981 attaaattta gtatttagta cattagcagg atattctttt gcgaagatgg attttaaagg
     5041 tagtgataag ttatttttat ttatgataat gactttaatt ataccttccc aagttacaat
     5101 gataccacta tatataataa tgaaacactt aggatggata aatagttatc ttgcacttat
     5161 tatgccaata ccaactgcat ttggcgtatt tataatgaga caagctattt taggagtacc
     5221 aaaagagtta ttagaatcag caaagataga tggttgctcg gattttagaa ttttaataca
     5281 aatagtattg cctttaatca aaccagcatt aattacacta gcaatattta cttttatggg
     5341 agcatggaac gagtttatgt ggcctcttat agctacaact aaagatgcaa tgagaacatt
     5401 aacagttgga ttatctactc ttaagacatt ccagataact aattatggac agatgatggc
     5461 aggggctaca ataacatttt tacctccatt tattttctat ttgattttac aaagtaaatt
     5521 tgttgaaggt gtgtctttgt ctggtataaa aggttaaata gtctaattta ataatatata
     5581 aagaaactta tataaatatg gaggaattta aactatggaa atttcatatg tactgaaaga
     5641 ttgcacattc aaacacaata aatattcagt tatagaagct gaaacttgga aagataagga
     5701 tttggatatt gtagtagcta aaggtgaaaa atttgcattt caaattatgt taaaagcaac
     5761 agaagaattt aattgtacaa ttgataaaag cagtactata tcatggaaag gtctgggaaa
     5821 tagagtaaga ttagcattaa atgtgcctaa tagtttagaa aataatttta gtataaatat
     5881 attaggatat gttcaagatg atacaaaggc atttgtgaat gatgctattt taagggataa
     5941 agatgtatta gtagagcaat atttgcctca aacattttgg attgaaggtc aagtaccaga
     6001 agattttgaa gaaaataacc ttgatatagg tattgatata tttaaaagct ttggatatga
     6061 agatgaagaa aaagtttgta caattgatgt tcctgtaaaa gtaagaaatg ttgtgctaaa
     6121 gcctttagat gaaagcaagt tctttttaga tttatggcaa catccaagtt gtttagctag
     6181 aatgtataaa gttgagttat ggtctgatat acattttgaa atagtcgata actatttaaa
     6241 agaattagca tctttaggag aaaaagttgc aacagttata gtttcagatt atccatgggc
     6301 agggcaaagt tgttataaag tttataaaaa tccatcaaac ttatatgaat ataacatggt
     6361 aagtgtatca aaaggattgg atggaaagat taaatgtaat tttgagagta tggataggta
     6421 tataagcata gctgataagt ataaaatggc tcaggagata gatttatttg gtctattagg
     6481 taattggtgt gctggtgagt ttggaaatcc tgtagaaggt tataaggatc ctataagagt
     6541 aagatatttt gatgaaaatg ataaagtatt taaatttata aacaatacaa atgatttaaa
     6601 agaatatata ggattagtat taaatcattt aatagagtgt ggattatggg acagagtaag
     6661 gattatagct gatgaaccaa ataatccaga agtagtcaaa gagtgtatag aatttataaa
     6721 ctctactgta ggtactcgtc aagttaaata taaatcagca actcacgacc aaaacttttt
     6781 agatagagct aaagatgaaa ttgatgatat gtcaataaat ttaaaactta ctatacaaaa
     6841 ttataaagat atagaaaatc ttaagaaaaa aatcaatgac aagggtggga tattgacttg
     6901 gtttgtatgc tgttttccag agaaaccaaa tagtttttta agttctcctt ttgtagaaaa
     6961 tagaataata ggatggtata cttattactt tggtcttgat ggatttttaa gatgggacta
     7021 taatttatgg acagaagacc cttggaaaga ttcaagttac aaattcccta tttggaaagc
     7081 tggagatatg ttctttgttt atcctggaaa agatttaaag ccagttagaa gtgtcagaat
     7141 ggagaattta agatttggaa tacaggactt tgagttattt acaatgttag aaaaagaaaa
     7201 gggcagagag tatatagaag ttgagcttat gcaagaatta ttaaataaaa aagaaaatgc
     7261 tgaaattaaa ggttttggtg acatagaatt aggatattca cttgataatt ggggatatga
     7321 taaagttaaa aaatatgtat tagagttgtt agacagagta taaaaaatat aagagtgtct
     7381 caaaatgaac tttttagttc atgaggcact ctttttgtat gaaatcaata tagtttcatt
     7441 gtttcaacaa tgaaaaatag gattacttat attctaagat agccctttag ttttttagtt
     7501 gtattcaatg ttttaaaact aactataaac gctataaagt ttataaatga caataattat
     7561 atgtaacatg atgtacttta atttgctata atagggattg aataatatta tatggaagat
     7621 aacattgttt ggggggatta atataaaaag aataggtatt attataatgt tttttttaag
     7681 tatagctttt attggatttt atcttgcaat aagaggtaac agtgatacag ttaagatgca
     7741 acgagggata aatataggta atgcactaga atcacctaag gattttccgt gggatgtaaa
     7801 aatgtcaaat aagttttttg atgatataaa agatgcaggt tttgacacag tacgtatacc
     7861 agtaaggttt tctgattata cgtcagattc tgataatttt aaaattgatg aagaattttt
     7921 taaaaagatt gataaatatg tagattatgc attagataaa gacttaatag ttgtgttgga
     7981 tttacatcat tttgaagaaa ttatgaaaga accaagagtt cataaagaag agtttttaaa
     8041 aatatggcaa cagatagcta ataggtatca aaaatatgat aaaaaattgg tatttgaatt
     8101 attaaatgaa cctaaagaaa atttatcttc acaattacta aacgaataca ttgaagaagc
     8161 aataaagata attagaaaaa ctaaccctaa aagaactatt atagtgggac catataattt
     8221 ctatcaaatt gattatttga atgaattaaa tgttccaaaa gattctaata tagtagtttc
     8281 ttttcactat tacgaaccaa atgattttgc atttcaagga aacatttatc ataatggatt
     8341 tgagcacttg agcaatatta cttgggaagg aacaaatgaa caaatggatt atttaaaaaa
     8401 aaggtttgat attgtagaaa attgggcaaa taaaaataag gtaaaaatat tcttgggtga
     8461 atttggagta acaaaagaag caccagaagc ttcaagaaga gcttggataa aagctgtaag
     8521 agaagaagct gaaaaacgaa acttttcatg ggcttattgg gagcttgctt ctggatttgg
     8581 tatatacaat caaattgaag ggacttggga tagagacata ttaagtgcat taatagaaaa
     8641 gaggtgattt tatgaagaaa aattcaaaaa agatacttat aactttaact attattacta
     8701 atatcgtata tatattgtgg agaatttttt acacagtacc taaagaagaa gggatgtttg
     8761 ccttaatctg tgctataata cttctttttg tagagataat gggtatgatg gaaatgtttg
     8821 tacattatta tggtatgtca aatattgagt atcctgaaaa accagtcata agtgaagaac
     8881 tttatccaca tgtagatgta ttcattgcaa catataatga gtctgttgat ttggtgagaa
     8941 aaactgtaaa tggatgtatt catatgcagt atccagataa gaaaaaggta catatataca
     9001 tatgtgatga tggaaatcgt gaagaaatgc gtattctagc agaaaaaatg ggtgtaaatt
     9061 acataactag aactgaaaga gaaggagcaa aagctgggaa tttaaataat gcaatgcaac
     9121 atacaaactc tcctttgatt gctacgtttg atgcagatat gataccaatg catgactttt
     9181 taattgctac agtaccatac tttttgaaaa atgagcaagc taaaaaagat ggagaaaaag
     9241 aggagtatga aaaggttggt tttgtgcaaa ctccacagag tttttataat ccagacttgt
     9301 tccaatttaa tctgcactct gagggaagga ttccaaatga gcaagattat ttttacagag
     9361 atattcaatt ggctagaaat aggacaaatt ctgtaattta tggtggtagt aatacagtta
     9421 tttcaaggga agcacttgaa gaagttgatg gattttatac ttattctatt acagaagatt
     9481 ttgcaacagg tatcttaatt caaagtaagg ggtatagatg ttatgctatt ccagaagtac
     9541 atgcatcagg tttatctcct acagatttaa aaagtcttat taagcaacgt gaaagatggg
     9601 cacgtggatg tatacaaact ggtagacgtc taaatatttt gtttaggaga ggtttaggtt
     9661 tttggcagaa aataagttat atttcttcaa ttacttattg gtatgcaagt ataaaacgct
     9721 ttgtatatat aatggcacct attttatttt ctgtgtttaa tgtgattgta gtaaaatgta
     9781 cattacttca agtattggta ttttggttgc caatgtatat tttaagtagt ttatctctta
     9841 aaatattttc tcaaaatata agaaatacta gatggaccaa tatatatgaa actataatgt
     9901 ttcagtcttt aatgccagca gtaatacttg aaacgtttgc aatatctaaa aataaatttt
     9961 cagtaacaaa taagaataaa ttagaagaaa atagaatgta taagttttta cagggaatac
    10021 cttattttat ttacatggtc ttatctatca taggaatttt aaaaatgttt gtagcaatat
    10081 ttaaaatgag ttcaatgaca tattcagttg tattattttg gttgattgga aaccttttta
    10141 accttgttat ggctacatta tttatatcag ggagacaaca gttaagaaag tctgagcgtt
    10201 atattgctga aattgatttt aagttaaagc aaaactctta tgttctttct tcaaaaacga
    10261 ttgatatatc agaaaatggg tttgcatttt tgctagaaaa tccagaatat atttccccag
    10321 aagaagagtt cgaggtagag tttagagaaa aatcaggaaa tgaaatgtat atagctaata
    10381 tgaaagcaaa gattgttaat gttgtggaag taaattcaaa gtggaaatat gcagcttata
    10441 ttacacatat tgaagatagt gaaatagata attggatgtg tattgttcac gatagaatac
    10501 ctactttacc gatgacaata tctaatcaac taggtttctt tgatgatttg caaattaatg
    10561 taaaaaaacg tattgaaaag attagaacat tatcacgaag aagtccaaga atcaatatga
    10621 attttcagat ggatataaaa aatacaggta aattaagaat agtaaatttt aattatcaat
    10681 atgtattatt aaattttgag aataaaaata tttatcctaa agaaatagca ttggaaatta
    10741 atgaaaatat tgtgttagaa tgtgatttat gtgagggtaa aatcgatgaa agaggtatct
    10801 tatataaagt aaataacatt gacagcataa tgcaaaattt ctttttaaga gatgaaatga
    10861 tggattggat attacaaaat aagacaattc ctgtttcaaa tcctagtgaa aagaaagaaa
    10921 aaagtataga tgagtttgaa cccatggaat atatttagga gagatgaaat gaagacttta
    10981 aaagtgtttt tttgttctgc aaaatatctt attttggtgt ttattttttt tataaatact
    11041 acttttataa gttcagcgac aagtgataaa attttagatt tatcctttaa aaagatagag
    11101 actgatttaa gttctaggat tacatatgaa gatacaggtg taaaaataga aacagatagt
    11161 tctaaaagtg ataaggaacg ttatttatat atttaccaaa atataaaaga aaattggagt
    11221 atgtataata atttttatat tgaaattcaa aataaaaata aaagttccca gaaaataaat
    11281 ttaagtatac aaagtaagaa tatgcttgaa tttaggttaa aagaaggtag tgaaatattt
    11341 ttggaagata aaaatataat atattcagat aaaataaaag aaggatgcat agaagtacca
    11401 ggtgaatttg aaggcaaaat ttatgtgaac tttaatagcc ttataaatga gaaaagtaat
    11461 gttgtgctgg actcaagtat gctttcaaac attgttagtt ggggaattac atttattcca
    11521 tctgatgaag aacataatat tgttattata aaaaagatat ctttattgtc tgaagagaaa
    11581 ttaagttttt tacataatat taaaataact ggcaatgaag aagtacaaat accagtattg
    11641 ggtcaaagta taagtcagta tgaggtatta ggtcttaaac gtgattctaa aattaagtat
    11701 tctcttatgg gaaaacaaga taatgtgagc atatctcaaa atggtaaatt aacattaagt
    11761 aataaagccg aacctggaca aattatttta caagttaatg ttgatgataa gtttaaaatt
    11821 ggaaggaaaa tagcattaac tgaatcttgg agtattaata aaaaagataa ggatggtgtt
    11881 ccatatacat tggtatctcc tgagcaatca ccaacagtac aagatatgaa aaaaataaac
    11941 tttatgaata acatcataac gtttgttcga attttatttg tatctctagt aataatatgc
    12001 tttggaatat atttatattg gaaaaaatgt tcaaaaacta agtaaagaga ggaggttaga
    12061 ttgtgttatt ttcaagttta atttttttat tttatttttt acctataact ttggttttat
    12121 attatgtatt taggtttaac cgaacgatac agaacatgat attgcttgct gttagtttat
    12181 ttttttatgc ttggggagag ccaaaatttg ttgttatcat gatagtttcc ataataatga
    12241 actatatatt tggtttacta gtagatagat atagggaaag taaaataaaa gtaaaagttt
    12301 ttttagtttt gatgtgtgta tataatatag gtgttttatt tatatttaaa tatctagctt
    12361 ttgcgctaag aaatattagt gaacttatta atactgaact aactatacct agtattgttt
    12421 tacctatagg aatttcattt tttacatttc agggaatgtc ttatgttata gatgtatatc
    12481 gtagacatgg agaagtccaa aagaatcctt tttatgtggg actgtatata gcatttttcc
    12541 cacaattaat agcaggtcct atagttagat atgagagtgt ggcagaacaa attctcaata
    12601 gaaaagaaac ttggaataaa ttttctattg ggacttgcag gtttataaca ggtctaggca
    12661 aaaaagtatt aatttcaaat aacatggcta tagtagcaga ctatatttac actatgaata
    12721 gtcaaggaga aatagctgca tcacttgcat ggcttggttc aatagcctat actatgcaaa
    12781 tattctttga tttttctgct tattcagata tggctatagg tttaggtctt atgtttggtt
    12841 ttaaatttga agagaacttt aattatccat atatatcaaa atcaattagt gagttttgga
    12901 gaagatggca catttctttg ggaatgtggt ttaagagcta tatatacttt ccgcttggag
    12961 gttctagagt agcaaataaa gatattatga ttagaaatat gtttatagtg tggttattta
    13021 ctggaatatg gcatggagca gaatggacat ttgtaatttg ggggatttta aactttgttt
    13081 tcttgattat agagcgattt ataatgtttg aaaagattga aaatcacaat tttataaaac
    13141 atatttatgc gttattagta gttaactttg ggtgggtatt gtttaggtca cctaatttaa
    13201 aagaagcata taattatttc aaagctatgc ttggaggcaa tggagttata tggagtgatt
    13261 atacatatat gtttttaaaa gaatactggg ttttctttat atttgcattt atttttagtg
    13321 tacctattgc aaagaaaatc aataagtttg ttgttgaaca agctaaatat agtatgatat
    13381 ttaacgtatt ttatccaatc tcagctattt tattgttctt tatttctgtg acatatttag
    13441 taactggaag ctataatcca tttatttatt ttaattttta gttgggagga aaagtatgaa
    13501 tagatttttt aaagtaagat taataactgc aattatgttc ttaattattt tattcgcttt
    13561 ctctatcttt aatatttgtt attctggaaa agatatgata caggagataa aaaattcagt
    13621 tgctgaaaaa agtagtttaa aagatacaat atcatctatt gataacacag taaatgacaa
    13681 agtaatatat aaaaatacgt tcattgaaac ttatggctac ttacaaaagt taatgggtaa
    13741 aaatgagttt tcaaaattta gtgttgtaaa agatacttct ggaaagatgc attatacata
    13801 ttttgctaaa gctccaaatc cagttggtgt gatagcagat agggtaagaa aattttctga
    13861 ggaaatggaa aagcaaaaca ctaaattagt ttacttaatg actccagata agtatataaa
    13921 aggagtgaca aaatttccaa aaggaatacc ttattcttat agcaatgaga cagcagataa
    13981 ttttttaaat caactaaaaa agtataatgt ggactatatt gattttagag aaaatatttt
    14041 aaagagtggt attccaaaag atgatttatt ttttaaaaca gaccatcact ggaaagtaga
    14101 aacttctttt tgggcatttg gagaattagt tgagcaactt aataaaaaat acaatatgaa
    14161 tttagatgaa aatcattact atagagataa agaaaattat aactcaattg tatatcctaa
    14221 gtcatttctt ggttctatgg gaagaaagac tggtatctta tatggtggta tagatgattt
    14281 tacattaatt tatcctaaat ttaagactaa ttatacttat tatacagatt ctaaatctca
    14341 aaaatttgaa ttaaaaggaa ggtttgaaga gagtttaata ttatcatatc cttttaatgc
    14401 agaccttgat ttaatggatg gtcaatcaga taagtatttt acatatttat tggggaatag
    14461 accattagtt aaaataaaaa atatagaaaa tccagatgga ttaaaagtgc tgtttgttaa
    14521 agattctcta attgtaccaa cagcagcatt tttttcctct gtttgttcat ctatagatat
    14581 gatagaccct agatattatg atggagatat actagaatat gcaaaatccc atgactatga
    14641 ctttgttttt atatctgtat atccccaaaa tcttacaaaa gaattttttc cgttttgtaa
    14701 gtaaatttct aaagaaattt tcttataaaa taaaaaataa atggctaact agttaaaagt
    14761 tagccattta tcttaagtgt tactctaaga aatgtttttt ttaccaaata cttctttatc
    14821 tatttttcca agtgattttc ctacagtaat tgatgatacc atagcaccat taacatttat
    14881 catggtacgt cccatatcta gtatagggtc tattgcaagt ataccaccaa ctaatggaaa
    14941 ataagaacca agaccaactc cagagataac aactgaaacg gccattgtag cagttcctgg
    15001 aagaccagct attccaaacg aactaattgt tataacaatt aacaacataa cataaaagct
    15061 catatccatg tttactccag ccatattggc aagtgttaca gccattaaag caggatatat
    15121 acctgcacaa ccattcatac ccatatttgc acctaaactt gctgtaaagc ttgatacacc
    15181 ctcatcaact ccgtgatttt gtactagact ttctatcgtt acaggcaatg ttcctaaact
    15241 agaacgtgaa gtaaatgcca gaagtaaagc ttcagttgaa tttcttatat aagtaatggg
    15301 atttagacca tttaaagtta taaaaattaa atgtatggta aataatattg ccactgatat
    15361 ataaagagct aatataaact gtaaaacaga tactattgag ctaatacctt gtgaagttat
    15421 tgtatttgca agcagagcaa ccacagcata aggcataaat ttaataacag tcatagacac
    15481 acttacaatt attttgtaag atgcttctat aaaatctata aatggtttta ttgtttcaaa
    15541 gtatttttta cttaatctct ttattgaggt agctataaat gtagcaaata ttattgtagc
    15601 tacaatattt ccatttgcca tagccattac aggattagat ggtagtaatc ctcttaaagt
    15661 atccacaaga gagtttattt ctttaagttc ttgattttca actaaagtag gcatattagc
    15721 tcctacacct aacttcatta tatttgcaac gataattcca acaattgcag ctatagcagt
    15781 agtagcaaga agcataccta aagatttaaa tgtcagagtt ccaagattgt tatctttcat
    15841 atttataatt acttttataa tggataagaa aactaaaggt actactaaca tttttaataa
    15901 gtccataaat ccagaaccaa ataggctata ccacttgctt acttcttgta gccaagtgac
    15961 ttgagtggta tcattaggaa aaccagcaaa agcttgtatt atgattccca atatgagtcc
    16021 tagtactgta gcatatattg ttctcaatga aaattttatt tttttctttt caaattgtct
    16081 aacaataaag aatgtaccta gaagtaatat tatgaaaaaa atcgttttaa aatctgtaat
    16141 cataagaaat tgtgataaaa atgaactttc caatattttt tctcctttta tttaaaaata
    16201 aatttttcta agtttaaatg ataccaatat attaaaaaaa tgtcaatatt atatcacaat
    16261 ttacttaaat agagtaaaat aaattgattt tgaaaaatgt gattaagtat agaaaaatag
    16321 ggtataataa atgtttaaag aatttgaatt gtggtaagaa aataaaaaat agcttttata
    16381 agatttgatt tcaaattaaa atatgttaaa taaataacta aaaattgtta tgaaaaatgt
    16441 ttacatagaa tatatatcaa atgaaaagct taaaataagt gaagaaatta actagacatc
    16501 aaaggagaga taaaatgaga gtagtaataa ttggtggtgt tgcagctggt atgagtgctg
    16561 cagcaaaatt aaaaagaata aaacctgagt atgaagttgt tgtttatgaa aaaactgaaa
    16621 tagtatcttt tggtgcttgt ggattaccat actttgttgg tggttttttt gatgatgctg
    16681 atgaattatt agcaagaaca ccagagaaac ttagagaagc tggaattgat ttaaatatat
    16741 ttagagaagt cgttgaggtt gatagtgaat ctaagaaaat aaaagtaaaa aatataaaaa
    16801 cagatgaaat atatgaagat tactatgata aattgatgat agcaactgga gcaagaagta
    16861 ttatgcctcc tataaaaaac ataaaattga agaatgtttc tacattaaaa agtttatatg
    16921 atggagaata tctaaaaaaa cttttaagta atgaagataa taaaagagtg acaataatag
    16981 gagctggttt tatagggtta gaagcagttg aggcatgtaa gaaattaggt aaagatgtag
    17041 atgtaattca gttagaagat agaatattgc cacaagtatt tgataaggag atgacggatg
    17101 tattagaaga agaaataaat agacataatg ttaatttgca cttggatgaa atggttgtag
    17161 aactttgtgg agaagataaa gtagaaaaag ttataacaaa caaaggggaa atagatacag
    17221 atgtagtaat aattgctact ggtgtgagac ctaataccga gtttttgtca aatactaata
    17281 taaaaatgct aaaaaatgga gctatagtag ttgatgagta tggaagaact tctgtagaag
    17341 atatatactc tgctggagat tgtgcaacta taaagaatat agtaagtaat gaaaatgtat
    17401 atgttccttt agctactgga gctaataaat tgggtaggat agtaggagaa aacctagcag
    17461 gaagagaagt atcttatcaa ggttcactat cttcaagttg tataaaaatt atggatatgg
    17521 aggcagcatc aactggaatt acagaaaagc aagctaaaga tttaggcata aatgtcaaat
    17581 ctaaatttat ttctgattat aatcaaactc attattatcc aggaagaaat aaaatatatg
    17641 taaaacttat ttatgatgca gatacaaaag ttattttagg cggacaagtg gctgggttta
    17701 aggatgctgt ccaaagagca aatgtattgg cagctgctat ctttggaaaa atgaccacaa
    17761 gtcaacttgg gatgttagat ttatgttatg ctccaccatt tgcaagaaca tgggatgttt
    17821 taaatgtagc tggaaatgta tctaaataat atttagatta tagctaatat agttgacaag
    17881 caattaaggg aatgaattta cctaaactat ttttatcatg gtaaaattca ttcctaaatt
    17941 tttattccaa atttttagaa ataaggattc cattaaatta ttcatcaaaa tttaaacgca
    18001 agcttaatct atcttctcca agaatagtat tttcaaaaac attagtagca ttttctaaat
    18061 acatactagg tatgtctaaa gaaggactaa aatgtgtcag taaaagttgt ttgacatttc
    18121 caagttttgc aagattagca gcttctctaa aagtcatatg tttgtttcta acagcttttg
    18181 atatatctaa atcatcacca tacatggctt cacatataaa taaatcacta tcttttatga
    18241 aatctggtat tgattctata ggtcttgtat cggttgtaag acttatctta actccctttc
    18301 tcaattctcc taagaccata tctggagtgt attgttttga atttaaaact atattttgac
    18361 cttcttggag tttgttccat aatattttag gaacttcgtt tttagttgcc ttatctatat
    18421 caaatttagg gtttcttcta aaattaaaac tgtatcctaa acactctata gagtgttcta
    18481 aactgattgt tgaaatttct aaatttctta aaactttatt atctaaagaa aaattgcctt
    18541 gagggttttc tataattttt aaagtgtatg gtacatattc tactaaattt ctcatagaac
    18601 gtatacaatc gactattcca actggaccaa ctatagttaa atcacttgta cgaccactat
    18661 ttccaattgt tgataaaagt cctaaaagtc caaatatatg gtcaccatgt aaatgggtta
    18721 tacaaatcaa gtctatatct ttaaagccac atttttttag cttcatagat acctgagtac
    18781 cttcaccaca gtcaattagt atttttctac ctttatagtt tataaataca gaggatagaa
    18841 atctgtttgg cataggtaca tttccaccac atccaagtaa agttaaatct atcatttttt
    18901 cccctttcta aaattaacac aaatctgttg tttgttttta ttatgatatc ctattataat
    18961 tattttaaca ttaaatataa caataaatgt gtatttgagt caagaaatat tatcaaataa
    19021 agtttttata tagcaatgta taaaaatttg gagaacgaaa agtgaaaatt atatttagga
    19081 gtatttaaag gaggaaaatt taatgaaagt attaaagaaa attactattt tgtcattgat
    19141 tacattaacc ttagttggtt gtagtaacgg agaagataaa aaagtggttg aaggttctaa
    19201 gaaaattcaa aattctaaaa aagatgaaca gcctataata gtacataaag atgcaaatat
    19261 attgaaagat aggtatgagc caccaaaagg atttaaaaga gttgatgtag aaaaaggtag
    19321 ttttgaatca tttcttagga atactaagct aaaaaattat ggagagaaag taaagtatta
    19381 tgatggaaga attaaggaat caaaaggtat ttatgatagt gtatttgatg ttgatattgg
    19441 caatagagat ttgcatcaat gtgcagatgc gattatgctt atgagagcag aatacttgta
    19501 tcagaataaa ctatatgatg aaataagttt tgattttgtt gatggtttta aggcgaagta
    19561 ttcaaaatgg gcacaaggat atagaatttc agtaaaagat agtggttcaa gctggtataa
    19621 agcaactgaa tattcaacat cttatgagag tttcagaaag tttatggata tagtgtttgc
    19681 atattcagga acgttatctc ttgaaaaaga attggagcct gtaaaagttg aggatatgaa
    19741 aataggagat gtgtttatag ttggtggaag tccaggacat gcaagtataa ttatggatat
    19801 ggcagaaaat gaaaagactg gtaaaaaggt atttatgata gcccaaagct atatgcctgc
    19861 acaacaaacg caacttctta ttaatcgtaa aaatccaaat ttgagtcctt ggtatagttt
    19921 agattttgaa ggtgatttga caatacctca atggactttt aaaagagacc agttgaaaag
    19981 attttaaaat aataatttta tataataaaa gaaaaatata gatgtgaaaa aatgtaatta
    20041 gattaaaact aattggatat ggacaaaatt aaattgatag ataaatatta aaaattacac
    20101 taatcaatct tactatagtt taatatttat ctaaaaagtt ttatgtaaaa tataaatttt
    20161 atattaaagc taaaactaat ttgaggaggc taatttatat tgaagattag aaggtattta
    20221 attttggtaa ttataattct aattacaaca agtcagagtt ttatttctta tgggctagag
    20281 cgatttgaag aaataaccat ttttcacact aatgatatac atggaagata tgctgaaggt
    20341 gatgaccata tacaaatagg aaatctagcc acattgaaaa aagaaactcc aaactcaatt
    20401 ttagtagatg caggagattg tttgcatgga cttccaatag taaatatgga tagagggaaa
    20461 agtgcaattg aattaattaa atgtgctgga tatgactata ttactcctgg aaatcatgac
    20521 tttaattatg gaaaagatag actgtttgag ttatctaaaa gtgctaattt aggagagaat
    20581 actttaaaat ttttatcatc aaatattttt gaaaatggaa aaaaagtttt tgatagtaat
    20641 gatataaaag aaatagatgg aataaaaata ggattttttg gactctcaac ccaggaaaca
    20701 aagaacaaaa ctggatttaa aaatgtggaa ggattagagt ttaaaaatcc tatagaaagt
    20761 gcaacagaac aagtaaatga attaaaagga aaaggtgcca atgtaatagt tgcaatatgt
    20821 catattggta caagtagttt aagtaagcca aatagtatag atatagcaaa tgaggttcaa
    20881 ggaattgatt tgattattga tggacacagc cacactaagt ttgaaaatgg taaacaagtg
    20941 ggtgatacat tgattgtaag tgcaggacaa tatttagaaa atattggcga gataaaacta
    21001 actttggata ctaatgatgt agaaaatata aaaatagaaa ataaatcagt tagattaatt
    21061 ggaaaagaag aagcattaaa gtataagctt gactacgttg taagtaaaaa ggttaatgaa
    21121 ataaaagaac aacaagaaaa aatattagat aaagttatag gtgcaactac aaatactcta
    21181 gatggttcat atgaaaatgt aaggacaaaa gaaactaatt tgggtaattt aataagtgac
    21241 attttactag ataaaactaa ggctgatatt tctttattta atggagggaa tattcgagat
    21301 acgatagaaa aaggcaatat aacaagaaga gatattgtag atgtatttcc ttttagcaat
    21361 actatagtta ccaaagaact tacaggagca cagattaaag atgtattgga gcatggagta
    21421 aaactttatc cagaaaaaag ttcagccttt ttgcaagtgg gaggaatttc atactacttt
    21481 aatcctaaac aaaaagaagg cgaaagaata acaagtattc aaaaagaagg aaagccatta
    21541 gatttaaata aaaagtatgt agttgcaacg aatgattata tagcctcagg tggagatgaa
    21601 tttccttgtt tttcaaaaga gccaatacta aaggaatttg gaaatttaga gagtgcagtc
    21661 attgaatata tagagtacaa aaaagaaata tcaaaaaatg tagatggaag aattggtatt
    21721 aaatctaaag atgagttaat aagcaagaat catgagagtg atttgatatt aagtgaaaat
    21781 gaaaaaaata tcaatgataa tgaagagaat ctatctaata atataaaaag ctctgatagt
    21841 gacaaaaata aaagcttaga taaaacaagt gctagagaaa gttctaatct aggaatatct
    21901 aaaagagaag ctaaagaaaa atctcctaaa acaggagatt taggtttttc aaatagtata
    21961 attatattta tagtttcaag tacattgata tgtttattga attttaatca aaaagagtta
    22021 aaggataaaa agtcaaaata aaaattaatg agcaaaatta gtagatagta atttaatttt
    22081 agataatagt aaacagcaaa ggaaattagt tatataaata ctaatttcct ttgttttatg
    22141 ctttaacatg attattttta aataaaattg tattttatga aaaataatta cactaaatgg
    22201 catagtatta tggggatttt tagtttttat tcaagtaaat gaaatcatat taacaacttc
    22261 tgatatattt acaaattgat aaaaaaatga ttttattagt atgatataat ttagctagta
    22321 tatatgatga tggaggatat agggatgaat aatatattac ttttggaaga tgacaaatct
    22381 ttaaatagag gaattagttt taaattaaaa aaagaaggat acaatgtttt tagtgcattt
    22441 ggtatagaag aagcaaaaaa tattttcgca aaagaagaga tatgcttaat tatttccgat
    22501 ataggtctac ctgatggtag tggttttgac ttttgtgagg agattagaaa gaaaagtgat
    22561 gtttacataa taatgttgac agctcttgat gaagaggtgg atattgtcac aggatatgat
    22621 ttaggtgcag atgattatat cacaaagcct tttagcttga tggtattaat atcaaaagtg
    22681 aatgcgctta tgaaaagagt aaatacagta aaaaattata ctctattagt ttgtgatgat
    22741 ttattctttt attatataga aaataaatta attataagaa cagatgataa ggaagaagag
    22801 ataattttaa gtaagacaga gacaaaacta ttaaaatatt tgatggaaaa ttctatgcag
    22861 acattgacta aagaacaact gttagaatct ttatgggata gtagtggtaa ttttgtagat
    22921 gataatacga ttgcagtaaa tataagaaga cttagacaaa aggttgaaaa aaatccatct
    22981 gaacctaaat atataaaaac agtaagaggg gttggatata tgtggggaga aaggagtata
    23041 aaaaaatgct aaaaaatatg aacctcaaag atggtttaag tgtgaaagat gattatataa
    23101 tgagaagagt tattgtatat tctgttttat ctgtactaat agtaaccctt gtatttatac
    23161 tttttgaata tagcagatta cataaattgt atgaacatca aataaaaaat actcaaaata
    23221 ttgctggaat attgattgaa aaatatccta atgatgaaat agatatagta aattctattt
    23281 ataattccga ttatagtaag gtgtctactg gagaaaaggc atttaagaaa tttggctatg
    23341 gattggaaaa taaaatgtca aatgataaaa attttagttt atacttaaaa tcttttttta
    23401 aggaatcatt ttttattttt ttaatgatgt ttatagtagt tataggtata atatattatt
    23461 ttataagata cataaataaa agattgagta aaatttattt tatagtagat aagatggcac
    23521 aagaaaacta cttgaaggac actactgagt cagaagaaac tggttatcta gtagaatata
    23581 atgagtattt taaagaaggt acatttagta agataaataa ctgtctatat gagcttaata
    23641 gaagtttaaa gataaagttt attaaattag aaaaagaaaa agaaagtgta aaatcattag
    23701 taacagatat ttcccatcaa ttaaaaactc ctttagcatc cttaaaatta tacaatacat
    23761 tacttataga agaagaatta gaagaagatg aagccaacga gttcttatta accaataagg
    23821 cttctataaa taaattagaa aatttaataa attctttagt gaacatatca aggttagaaa
    23881 ttagcatgat aaacataaaa aaagaagata atgatataaa aaatactatt ctaaatgcag
    23941 taaaaagtgt tacccctaag gctaagagca aaagtataac attaaattta aatgaattta
    24001 acagtagaat tataccacat gataaaaagt ggactgagga gagtattttt aatgtattag
    24061 ataatgctgt aaagtacaca caggtaaatg gagaaataaa tatatctgta gaagaaactg
    24121 ctaatttctt taaaattata atagaggata atggcatagg gattgaaaaa aatgagttta
    24181 ataatatatt taaacgtttt tatagaggtt ctgctgatga aattgaatct gtagaaggta
    24241 gtggggtagg attgtattta agtagaaaga ttttagaaga acaaggtgga aatattatag
    24301 tttcttcaaa agtagggata gggagcaagt tttctttgtt tcttacaact atgtaatatt
    24361 aaatgaaagg aaaatgtaag cctctacatt tattatataa gtataaacag ctccagaaat
    24421 aaaaaattaa taaaatatgg ggtaatataa cttagaatga ggggataatt ttatgaaaat
    24481 actatatact gaaaatttat caaagcatta tggaaaagga gaaaacttag taagagcttt
    24541 ggacaatgtt aacttagaaa taaatgaagg tgaatttgtt gcaataatag gaaaatcagg
    24601 ttctggaaaa agtacacttt tacatatgat tggaggtctt gatataccta catctgggaa
    24661 ggtgtatata gataataaaa atatatttac attaaaagaa gaagaactag ctgtgtttag
    24721 aagaagaaaa atagggttta tatttcaaag ctataattta attccatctc ttaatgtatg
    24781 ggaaaatgta gtgttgccaa tcggtctaga tggtagagaa gtagatgaat cttttataaa
    24841 agaacttttg aaatcattag gacttgaaaa taaacatgac gttttaccaa atacattatc
    24901 aggtggtcaa caacaaaggg tggcaatagc aagagcatta gctacaagac cagctataat
    24961 acttgctgat gaaccaactg gaaacctaga ttctaaaaca tctgatgagg ttatgagtat
    25021 attaaaatct atgtctaaga agtacagtca aactctagtt atgataactc atgatgacag
    25081 tatagcccaa atggctgata gagttatatt catagaagat ggcagggtgt caaaggttgg
    25141 tgataaaaat gattaatact actaaaatag caaaaagtaa tttaaaacaa aataaatcaa
    25201 aaagtattct aataataatc actataatac tttctacttt aatgctttct tctattggaa
    25261 tttatattgt tgatgcagga gcatatcaaa aagaaaatac tataaagtat tcaggtaatt
    25321 atcaaggtat attagcaaat gtagatgaaa aacaggctga tatattgagt aatcatgcag
    25381 atgttgaatt aactggtgaa atgaatggag taggtgttga aaaactggaa gatgattcaa
    25441 atatttctct agcatacatg aatgaagatg ctttgaaatt aaatagtttt gaacttatca
    25501 aaggaaaatt gccaacaaaa gagaatgaaa ttgtgttaga tagtggagct ttaaaggcac
    25561 ttggttataa aaataaagac ttaggtgaaa agataaaaat atcttataat gactataaaa
    25621 atgataaaaa aattgaaaaa gagttcgtta taagtggaat cttaaaaact agcgaaatat
    25681 ctgaagcagg taaatattat tatgctatta tatcagaatt atatatgaga aatactagag
    25741 atatgtcaca agaagatttt aatatttatg taaaatttaa tgataaaagt aatttatcaa
    25801 tagagcaagc aaaagaaaaa ttagataaaa ttgctaatga tataggactt gatactatta
    25861 atactgctgt aaatgaaaat tatataaatg ctttaaaacc agatatggaa acgattatgg
    25921 gtggaggttt tgtaggatta gtaattgtat tatctagtat tttagtaata tacaatatat
    25981 tttatatttc aatagttaca aaagttcaag aatttggaaa acttagagca attggtgcaa
    26041 ctaagaaaca aataaaaaat atagtgttta aggaagggtt tatattagcc ggaatagcaa
    26101 taccaatagg aataatttta ggctatgtac ttgcaaatat tataataaaa tcatttatgg
    26161 atatagatgt aaaatcatca cgattaccag ttatattatc ggttgtggta ataagcttta
    26221 tatctgttgt tttatcactt ttaaaaccaa tgaaagtagc atcaaaagta tccattgttg
    26281 acgcagtaag atatacagga aataaaataa gtaataagag taagagaaaa ggatataaaa
    26341 atataaatct aaagagatta tcacatgcca atttagaaag aaataaaaaa cgtacttaca
    26401 tgacattggc atcacttata cttagtggaa ctatatttat aacagtatca actgctttag
    26461 aaagttttga tgctgagaaa atggcaagag aacactttcc ttatgatata gaagttagac
    26521 tatctggtta tgaaatgaac agtgataaaa atcctaaaaa taatttgaat attttacaaa
    26581 tggataatcc tctaagtaaa gattttttta atcaaataaa gaacatggaa ggaattaaaa
    26641 gaatagaatc tgcaagaagt gtaaaaattg gtatggagga ctatgatgtt gaatttaagt
    26701 atgacctttt acaaagtata aatgaaaatg atgtaaaatc attaaacaag aatctaatag
    26761 atggaaaaat aaatcttgaa agactgcaaa ctggagatga aatagtaatt actcatgttg
    26821 atacagcaaa agaaatggga gtaaaagcag gagataaaat aagattaact ttatatgatg
    26881 gagataaaaa gataaaaaaa gaatttaaag ttcaagcaat agctatgggg gttccaagtt
    26941 ttggtatagg gaaggatttt attgatagaa ctttaaaata cgattcaact agtagcttgg
    27001 gaatatatac agaagaagga aagtatcaag aaatcaaaga tagtatcaag aagattgcta
    27061 aaaataatgg atttttagag actgatttta tagatagtag aattgagtca aataaggctg
    27121 ttatttcatt tataaagata atgggataca cgctaacagg cataataggt gtgattggat
    27181 ttatgaatct tgtcaacaca atgataacta gcatagttac tagaaaaaaa gaacttggta
    27241 tgcttcaagc tattggtctt actaataaac aattagtgaa aatgcttaat tcagaggcaa
    27301 tgtattacac ttctggaatg atgataggaa gtattttatt tggaggtata ttagggtata
    27361 ttgctgttat atttctaaaa aagactggat tatcttatgc aacatattct ttgccaatag
    27421 taccaatctt gttgatgatt gtgtgtattc ttatagctca atttataaca acttatttga
    27481 taggacgaag ttttaataaa gaatctctta ttgatagagt aagatacagt gaataaaatg
    27541 caaatatttg tggttagttt aactagcaaa aagcatataa aaaatatagt taaagagatt
    27601 cataattaaa taggttaaag catagtacag agcaaacaat ttaaacggat gtttgctctg
    27661 tattttatta tgtaatcaat aatatatcta atatactgat attattcatg ttagaaaatg
    27721 tatcggtaca attctaaaaa agtataaaat tgtaccatat aaaatgaaaa ttttgtataa
    27781 taatcgtata gaaaataaat aggagctgat atatatgaat aagaagatta attatgcacc
    27841 aggaccaact gaaactaggg aaaatgtaag attagcaaga gcagaaaaaa caacaaatcc
    27901 agatatagat attgattttg ttgaatttta taaaaagaca tgcgagaagt ttggcaatat
    27961 agttggaaca aaaaacgatg tttacatatt gagtggtgaa ggaatattag ggcttgaagc
    28021 agcatgtgca tcacttaccg aaaaaggaga tagagtactt gtaattgaca atggtatata
    28081 tggagaaggt tttaaagatt ttgtaacaat gtatggtggg gagtatgtgc ttttttcaag
    28141 tgaatatact aaaagtatag atattgatga attgaaagca tttttagatg aggatagtaa
    28201 ttttaaatat gcaacagtag tgcattgtga tactccaact ggcgtattaa atgatgtaag
    28261 caaaatatgt ccattactta aagaatatgg aatattaact gtagttgatt ctgtagcagg
    28321 tatggtagga gaaagattaa gtgtggatga atctaaaata gatataatat taggtggttc
    28381 acaaaaagct atttctgcac cagcaggact tactatagtt ggaataagtc aagatgcaaa
    28441 aaattgtata aaaaatagaa aaactgatgt aataggtttt tattgtaatt taaatatatg
    28501 ggaaggctat tatgaaaaaa aatacttccc ttatacaatg ccaataagtg acataatggg
    28561 gcttgataaa gcacttgata atatattaga agaaggaata gaaaatgtat tagatagaca
    28621 tgaaaagata gcttatagtg ttagaaaatc tattgaggaa tatggtctag aactattttt
    28681 agaagaagga tattctaata cagtcacagc tataaaaatt cctgaaagta taggagcttt
    28741 aaaacttact gattatatgc ttaaaaatta taatacactt gttgcaacat cactaaatca
    28801 atatatggat actattttaa gaataggtca tatgggtgag aatgcaaatc taaataaaat
    28861 agagcatgta ctaaatgtct tggataaaag tttaagtgca ttaggattca aaggaaatga
    28921 aaatttgttg aatttattta ataagtatta tttttaatag atagggggat atagtatgga
    28981 agttacagct aagcaaaaat ttacaacgaa agacatggtg gaaacctcac tattaatagc
    29041 attagtattt attgcaacta aatttataaa tataagatta ccaatatcta taaatggtgg
    29101 gcttgtgcat ttaggaacag caatgttgtt catatcagca atagtatttg gaagtaaaaa
    29161 aggtgcttta tcaggagcta ttggtatgtc actttttgat ttaatatctg ggtggacttt
    29221 atgggcaccg tttaccttta tagttagagg agttatgggt tatttacttg gaaagattgc
    29281 atgggcaaat ggtaataatg ggaataattt tttaatcaat gtaataggaa tatgtgtctc
    29341 atcaatttgg atgttatttg gatattatat aacagaagtt atactttatg gtaattttat
    29401 agtacctctt acttcaatac cagggaactt aatgcaagta ttgataggtc ttataatagc
    29461 gcttcctatt tctaaggtat tgaaaaaatg tataaaataa atataaagtg aactaaaatt
    29521 tatgatagca taaattatac tgtataatat taagatggag tacataatta aaaaatttta
    29581 gtatagaggt tagttcacaa tgttatcagt tacaagatat tcaatcaaaa atgttcgttt
    29641 aaagccgtgg gtaaagttta tttggtattt tgaaacaaaa tcaaatatac tgttaaataa
    29701 taagttactt cctacagaca gtatagatat tattcttaat ctttctgatg ttatggaata
    29761 taaaattgaa aatcaagact atactgctag taatatgcat tttaatggaa taagggataa
    29821 acatggattt attattcaac atggaaatat acgtgttata gggatttctt tttatccatt
    29881 tggtctctat ccatttttaa agataccaat ttcagagttt aacagacaaa ttgttgactt
    29941 agaagcagta tcagaactat ttgccaaaaa attggaagag tcattaaatc caacacaatc
    30001 agtagaaaaa attgttttat atttagaaga aatgttatta tccatattag aagaagattt
    30061 aatttcaaat aaatctgtaa agcttctaaa ttcatttata tatgataata gatatagcaa
    30121 tataaaagca ttttgtgata atacaaatat aaatattaaa acattggaaa gaatctgttt
    30181 aaaatataca gggtatacac ctaagatttt aaagagaatt tacagattta aaatggcaag
    30241 taatcaactt atttataatt ataaagataa tgaacttttt gattttattt atgaaaatga
    30301 gtactatgac caagcacact ttataaaaga atttaaaaaa ttttcaggga cgtcaccaat
    30361 taaatttatt ggtgagaata agacgattaa agaaaatata aagtacagct atttataatt
    30421 atactgtcga ttttttacaa tacctccaat ttattttttg atatgatata ggaaaataaa
    30481 ttggaggttt tacatatgaa aattattaca gaaatagttg agtttaatgt ggaagaaaat
    30541 ttatcaaaag aagagtttat agaaattgta aatgacttag aattaaaatt tcattctatt
    30601 caatctggtt ttattgatac tgagcttctg tatgatgaaa agtctcaaaa gtggattatg
    30661 atacagcatt ggaaatctat ggaaaaactc aagagtgctt ctagtaagat gtttaaagat
    30721 tcttcaactg agaaatttag aaaagcttta aagaatcaaa ctgttaagat gaatataata
    30781 ccacaaatta aaagttggaa attatagaac tgaatgtaaa agatagttaa atagtattaa
    30841 accaaattag ccaaataaca ttttgtattt aaattgttat ttggctttta gtgtttactt
    30901 taatatgagt gttatatact agaaaaacca acaaactgtt agagtgtgga ttatcataat
    30961 gtcatatttg ggagctaaaa ggcttaatac tgatttgtca atatgtcttt ttagcatgtt
    31021 gaacaggtat attgccatgc tttcattatt ttattttttt gccttatact ggactacatt
    31081 tgcagtttcc taatatattt ggctcatatt taaatgccat tatctaaaag tactattgct
    31141 gtacgagagg caataggcat tttagaagaa ggaggagttg agctaaagta tacatcataa
    31201 tctcttaagt tttctttttt tgtgtttcct ccaaactcta ccatatcagt atttaatatc
    31261 gttttgtagt ttgtattttg aaactttgaa atatcaactg attgtattag attagggtgg
    31321 aaattaaata taaataaata tttgccctta ctgtacacca aaatcttttt atcattatcc
    31381 atatgtataa gttcatgact attttggata aaaatatcac tgtattttgt aagttcgagc
    31441 atagatttat caaaacttaa taattgttta tactttaagt tgttatcttc tgaaaggctc
    31501 cattgtcttc tggcatactt atagctccaa ttgttgcctt ctcgtggaaa atcaatccac
    31561 tcaggatgtc caaattcatt tcccataaaa tttagatatc cttcacctgc tagagaaaaa
    31621 gttattaatt taattaattt aataagagat attgctctat tgataacatg attatttgag
    31681 tttatttcca tattccagta catttccttg tcagctagcc aaaaaataat tgttttatcg
    31741 ccaactaatg cttggtcatg ggattcacaa tatcctatat ttttttctcc aggtcgtcta
    31801 gtagtaagtt cataccacat tttgcccaaa tcccagtctt catcagataa gttagagata
    31861 gtttttatcc aaaaatcagg tactcccatt gcgagtctat agtcaaatcc aattccgccg
    31921 tcttttatag gtatacacat accaggcatt ccactcatat cttctgcaat acttatcgaa
    31981 ttaggtttaa tttcttttat taattcattt gcaaattgga gatatgttat agcttcaata
    32041 tctgtattca tactaaaata tttttcataa ctatcaaatg aaactccaag accatggtta
    32101 tgatataaca ttgaagttac accatcaaac ctaaagccat caaaatggta ctcatttaac
    32161 caaaatttta tatttgaaag caaaaaatgt attacttcag gtttaccgta gttaaaaagt
    32221 tttgtacccc aagcaggatg atttcccttt gaacctgagt ggaaaaattg atgttcactt
    32281 ccatcaaact catttattcc ttctaaagta ttctttacag catgagaatg aactaaatcc
    32341 aataaaacag caatccccat tgaatgagca gtgtttatga ggttttttaa gtcttcagga
    32401 gtaccaaacc tagatgagat tgcataaaag tttgaaactt ggtatccaaa agatgcataa
    32461 tatggatgtt ccataatagc cataagctga atggtattgt atccagcttt ttttatctta
    32521 ggaagtattt tttcagtaaa ttcattataa gttccaatag attcgctttc agtagacata
    32581 cctatatgac attcatagat tagtggagaa gttatgtttt ttaagtcaaa atcattgtca
    32641 gtccagataa atggagtttt tggttgccat atttgtccat taaatccacc aaaatctttt
    32701 tgaattactc tttttatata taatggtata cggtcaaatg tttttccatt tgcagtaact
    32761 tgtaccttta cctctgattt gtgaggtaag ctattttgac caggaataaa tatttcccaa
    32821 ttaccagccc caatttttct tagaggatga gattttctat tccaattatt aaagtcacca
    32881 attagtgaca aactatctgc atttggagcc cattccctat agaagaatcc atcatttgtc
    32941 tgatgaaatc catagtaaag atgagcattt gcaaaagaac taaaatcttt atagtttttc
    33001 aatatttttg atttcatatc ctcataatgt ttcattcgct tttttatatc agattcaaat
    33061 ggttgtaggt atacatcaat atctaaaatt ttaaatcttt tttgactttt cattgtattt
    33121 ctcctccata ataaatatta catctaaaaa ataatattta tctcatacta tcttctctgt
    33181 ataattgata tatattatat aatcctaata aaaagcttaa gccaccaatg attaatttca
    33241 taatttacct ccctagtatt tatacttata tatcgtattc atcaaaattt aaaagtttgt
    33301 ttaaaactct tttaataata tcataatcaa agcctttata ggaaagatgt tgagaaattt
    33361 tttgatatat tttcttttta tcttctttct ttactctttc ataccttttt tttgctagat
    33421 acatagcatt ttcaaattca gtgtccttgt ctaattcaga tactgcttca tcgattgtac
    33481 ttctattgat acctttatta tataaattct gcttaattct gtttttgcca catttattta
    33541 ggttaacatt tgtgttaaca attttttgag ctaatacact gtcatttacg agattataac
    33601 ttttaagaaa atctatgacc ctctcaatta tattttcatc aaattctgat gatagttttt
    33661 cttttaattt tttttcagat tggtcagcat gagataaaat atttaatgct ttatttttag
    33721 cttttatata catttcatca tctaaaatag gttttaattc ttcttcattt atttcattcc
    33781 ctttttttaa attaaatgta taaacaagtt ctttaaatat agcaataaaa aatttatcat
    33841 ctacataaat attaactcta tcatcatttc ttttttgttg ttctattttt gtaattatac
    33901 ccataagtcc tcctttttta tatgtaatta tattaacaaa agcaactaat aaaatttaac
    33961 aaaaaactta tatttgtatg ttatatttta tcaaaattaa gacaaaatag taaaaagtta
    34021 tttttattaa aaagtaaagc agaatcatgt taaataatta ttttttaaag tgttttttag
    34081 catataaata taattatata cccaaaaaaa caaattataa gctttaagaa ataaaaaata
    34141 atggtacaat agtattataa cattaaaagg agacaaaata tgagaagtga aaatctagtt
    34201 aagatggcag agttgaaaaa tactgaaaaa ctagagaaat ttaatcgcca taaaggcaaa
    34261 atcaaaatag gtatattggg aggtactttt gaccctatac actatgctca tttagcaaca
    34321 gcagaattta ttagagacaa gtatgacatt gacaaaataa tctttatacc atcaggaaat
    34381 ccaccacata aattatgtat cactacagat aagtatgata gatataatat gacacttcta
    34441 gcaactgaaa gcaacgaaga ttttttagtt tcaaaagtag aaatcgaaag aaagaaaagg
    34501 acttatacaa tagatacatt aaaatactta aagaaaaaat acaaaaatgc agacatttat
    34561 tttataacag gtgcagatgc aatttgtagt gttgaagagt ggaaagatgt aaagaaaaac
    34621 tttgagttag ctacttttat agccgcaact agaccaggaa ttagtttgtt aaggtcacaa
    34681 gagactatag aaaaactaac taagaagtat aatgctgaca ttataacagt ttatgttcca
    34741 tcactggata tatcgtccac atatataagg gaacagctaa atgaaggcaa gtcaatacgt
    34801 tacttagtac ccgaaaatgt agaaaattat ttatatgaaa ataaactata tcaatatgga
    34861 gatgattaaa tgaacttaga aaatattaac caaagactaa atcaaatgct accagtgggg
    34921 aggcttagcc attcaaaaaa tgttgcaaaa tgtgctgaaa aattatgtga gatttatgga
    34981 tgtgacaaag aaaaagctta cttagcagga atgattcatg attgtgcaaa gtatttaagt
    35041 gacaaggaaa tagaggatta tgtaaataag tatgaaatat atttagaccc aatagaggat
    35101 ggaaatcgtt ccttgtctca tagtgtaatt ggggcgtaca tatgcgagta tgaatttgaa
    35161 gtagaagatg aagatattat aaatgcaatc aaatatcata caacagggag agaggacatg
    35221 tctcttttag aaaaaataat ttacatagct gatttaattg aagaaggaag aaaattccca
    35281 gttgtagata cattaagaga attagcttat ggagggaagc ttgatgaagc acttttaact
    35341 tcttttaata atactttaat gtttgtcatc aataaaaaag aagagataca tccaagaaca
    35401 gttatggcaa gaaactatct aattaaagaa aagttattat aaaaaagcta tataaaggca
    35461 aacatattaa taaatttaaa tttgactatg ttacaaaatc gtattaatat gttacaataa
    35521 ctaagtgtat tttaattagg aaagtgagga atttttatat gacagtggaa caaatgacaa
    35581 aaatagcata tgatgccata gaagataaac tgggtcaaga tacagttata ataaatatag
    35641 gaaaagtttc tagtttgtgt gattatttta ttattactac agcatcttct cagagacagg
    35701 taaaagctat tgctgacaat gtggaagatg aattagcaaa actaggatta gagccaagag
    35761 gtaaagaagg acaaggaact caaacttggg tactccttga ttatggagac ataatggttc
    35821 atgtatttaa tgaggaaaat agagggtttt ataatttaga aaaattatgg aaagatgcac
    35881 cttatataga tattgacaca ttagcataaa catgataata tatgttatta taattagaaa
    35941 atttcaaaaa ttatattaaa ttgaatagac tagagcagta aaagattata ttttttcaga
    36001 gagttagtgg aaggtgagaa ctaatattat ataactttga acttactaga ttaaaatcta
    36061 ttctccatgg ctggattaaa agctatctaa gagagtctat atatgtagta ggctaattag
    36121 ggtggtaccg cgaagattta tcctcgtccc taaacgtaag tttagtgacg aggatttttt
    36181 attttcaaag aattatttgg aaattataag taaataatac taaataaggt agttatacac
    36241 aattaaaaat aggaggcaaa atatgagcgt atataatttt aaagaagtag aatcgaaatg
    36301 gcaaaaaatc tggaaagata ataatcagta taaaatggat actgcacaaa ctgaaaaacc
    36361 taattattac acattagaaa tgttccctta tccatctgga aaaatacaca tgggacatgt
    36421 tagaaattat tctataggtg atgttgtcgc aagattcaaa aaaatggaag gatataatgt
    36481 acttcatcca atgggatggg attcttttgg attaccagct gaaaatgcag ctataaaaca
    36541 tggaatacat ccgcataaat ggacaatgga aaatatagaa gaaatgaaag agcaattaaa
    36601 tttattaggt attagttatg attgggataa agaagttgca acttcaacgc cagaatacta
    36661 tagatttaca caagaaatat ttttgaagtt tttagagcat gggcttgcat ataagaaaaa
    36721 atcatatgtt aactggtgtc cttcttgtga gactgttctt gcaaatgagc aagttgttca
    36781 aggagcatgt gagagatgta aagcaacagt attaaagaaa gatttggaac aatggtattt
    36841 taagactact gaatttgcag aagaattact taatgactta gatacattag atggatggcc
    36901 agaaaaggtt aaaacaatgc aaaaaaattg gataggtaaa agtacaggag cagatttagt
    36961 ttttgatata gatggaactg ataaatctat gacagtattt acaactagac cagatacaac
    37021 ttatggagtt acttatatgg tacttgctcc agagcatgaa ttagttaaag aattggttgc
    37081 agggactgaa tatgaagcag atgttgaagc ttttgttcaa aaaatgcata ctatgacaga
    37141 aatagaaaga acagcagctg atgtagaaaa agaaggaatg tttataggta gatatgttat
    37201 aaatccttta aatggcaaga aagttcctct atggatagct aactatgtat tagttgagta
    37261 tggaacaggt gctataatgg cagttccagc acatgatgaa agagatagag attttgctga
    37321 aaaatataat ttagacataa ttgatgtaat aacagaagat aacaaaatga taaattcaga
    37381 agaatttaat ggattagatg cttcagaagg atttgaagga ataatcgata agttagaaaa
    37441 agaaggtaga ggaaagagaa caattaatta tagacttaga gactggttag tttcaagaca
    37501 aagatactgg ggttgtccta tacctgtggt ttattgtgat gaatgtggaa tagttccagt
    37561 taaaaaggaa gatttaccag ttcttttacc aacagatgtt gagtttactg gaaaaggaga
    37621 atctccactt acgacttcaa agcaatttat gtcaacaact tgtcctcact gtggaaagcc
    37681 agctagaagg gaagttgata ctatggatac attcgttgat tcttcttggt atttcttaag
    37741 atatgtggat agcaataatg aaaatgaacc atttagtaag gaattagtta atagatggca
    37801 tccagtagac caatatatag gtggagtaga acatgctata atgcatttac tttatgcaag
    37861 atggtttgta aaggcattta agagtatggg aatggtagac ttcaatgagc catttaaaaa
    37921 cttacttact caaggaatgg tacttatgga tggttctaaa atgagtaagt ctaaaggaaa
    37981 tacagtatct cctatggata taatagatga gtatggagca gatactgcaa gacttttcgt
    38041 attatttgca gcaccaccag aaagagattt agactggtca gagcaaggtg ttgatggatg
    38101 ttttagattc ttaaataggg tttatagatt ggttgacgag ttagcagatg tggttaaaaa
    38161 ggatgtagag tttggagaat taaattccca agataaggat atgagatata ctatacactc
    38221 tacacttaaa aaagttactg ctgatttaag tgaaaaattc ggatttaata ctgctatatc
    38281 agctcttatg gaattaataa atgatatgta taaatataaa gagttagata atataaacga
    38341 agcagttata aaagaaggtg tacaaactat agtaactata attgcaccat ttgcccctca
    38401 tttaggtgaa gaactatgga ctatgatagg taaagaagga agtgtatttg atatagactg
    38461 gcctaaatat gacgaaaaag ctttagtaaa agatgaaata gaagttgttg tacaagttaa
    38521 tggaaaagtt agaggaaaat taactgttaa ctcaaatata tctaaagatg agatggaaaa
    38581 ggtagcttta gaagatgaaa aaataaaagg attagttgaa ggtaaaacta tagttaaagt
    38641 tgtagctgta cctaaaaaat tagtaaatat agttgttaaa taactcaaaa atatgaacaa
    38701 aaatataaat ttataaaata aatgaggct
//
LOCUS       DACTZW010000034        38637 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.034, whole genome shotgun sequence.
ACCESSION   DACTZW010000034 DACTZW010000000
VERSION     DACTZW010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38637
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.034"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            73..1542
                     /locus_tag="JAM15_09175"
     CDS             73..1542
                     /locus_tag="JAM15_09175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HAT6798420.1"
                     /translation="MSNVNKKLVIAIGAVALVAIIFIGIMCMQFKGEKIAKNTYVNGV
                     DIGKLTKSQAKQELAKKYKLENVEFNYNDKSWKVKSKDLNLSTDLDKTVENAYNLNRK
                     SSFFGNLSKTISTNFGKKSNLVVVINYDKNKLKAEMEKIAKEIDVDVKDATLDISGEK
                     VKVIPDSDGLKMDISKSMENFDNQTKKGNYKNELVVKATPAKVKKEQLANIDTNLGTY
                     STIFKTSQINRSINIKLATDNISNVLLMPGETFSFNKHTGKRSKENGYKSAPVIMEGE
                     MEEDYGGGVCQVSSTLYNSVLYAGLEIVNVKNHTIPSSYVPKGRDATVADSGIDFLFK
                     NNLKHPVYIKNYVSGNQIVCNIYGSAEDKQNITISTKLDGVSQTTMKRVNDPTMPKGK
                     EKVDKSGRNAYSVSTYRTFNDANGKKIKTEKIANSYYPKKEGIILVGTMEPKPEEKPN
                     TDENKNNQNTNNQNPNNQQKPETPPTDNKPNETQPQPQA"
     gene            1607..2200
                     /locus_tag="JAM15_09180"
     CDS             1607..2200
                     /locus_tag="JAM15_09180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HAT6798421.1"
                     /translation="MNLNNITNYVQSICENISNVLDVDVTLVTKDLTRIAGTGIFRGK
                     IGETISEKSVYSLVLKDGKSYVINKEIEENCNKCANRENCKELADICTPVKMGEHILG
                     ILGIAAFNEEQKEKILSKDKELTAFVRSMSDLISFKLDELYKQEVKTIDDLEREAIEN
                     AIKKYGSNTEGMKKVAEALNIGIATLYRKVKKFNIKS"
     gene            2337..3728
                     /locus_tag="JAM15_09185"
     CDS             2337..3728
                     /locus_tag="JAM15_09185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAT6798422.1"
                     /translation="MSIILVKDIKQDIESMPRKILDISLIEDNKSDLTFFNIEEEDGD
                     ETLKALKQSYVTTNYKEETLLNLQGALNSKSDTTSKELKLESYKRYNNALDLAYKNYI
                     TSAINMVNKALEINPKDIDILNLRGLLKLLKCDFAKSFESFYTALCYENNHISRKYVN
                     LISSEDFKTFLGRYNHSIRFINEELNYESIHILENIIEEEPELIEPYVILSLLYDKLG
                     NVKKREGYLDKLKELDKDNPVFEKNEEEKEDTSKKEEIKKVKRKKSILPYIIVGCVLI
                     GMGIYLIQSKKRIENLNNQISSKEEKLSETDKKLGETSKKLEKTNKELNEVKNKEPER
                     EITVADEEDLYYQALNLKKNKEYEKAIDNFKSVVSSGKTKKYISESIYQLAITNKLLG
                     NKDEAIKYYKKYINTYTKNDQYYDDSYYELGMLYYDNGDLKNAQQTFYSLRSEVPDSM
                     YNNSKIKEILSEK"
     gene            3910..4281
                     /locus_tag="JAM15_09190"
     CDS             3910..4281
                     /locus_tag="JAM15_09190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HAT6798423.1"
                     /translation="MKVFNQLVIILSIWVIGEYISSFIQGIILIPGSIVGMLLLFLLL
                     QFKVLDLSSIENVSGFFLDNMAIFFIPAGVSLIKSLDLIRENVLVLLLVICLSTLIVM
                     YTTGIIVEKMIKKKEEGQKNV"
     gene            4274..4963
                     /locus_tag="JAM15_09195"
     CDS             4274..4963
                     /locus_tag="JAM15_09195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HAT6798424.1"
                     /translation="MYNVLQTPVFGIIVTIVFFNLGRYIQRKTSNPICNPLLIAIVGI
                     ILFLSISKIPYENYKIGADSLNFFLGPVTVVLAVPLYKQFELFKKHMFEIIVGIGCGI
                     VISFVSVLIIGKIANSDVSIINSLIPKSITTPMGISLANSLNGIESITVVAIIFTGIF
                     GGMVASTVFKLGNINHPVAKGIALGTSAHALGTTKAFELGEIEGAMSGVSIGVSGTIT
                     VILIPIIMNFI"
     gene            5483..6349
                     /locus_tag="JAM15_09200"
     CDS             5483..6349
                     /locus_tag="JAM15_09200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAT6798425.1"
                     /translation="MSEVKNTLQKHPVLRYSTMLFGMLMTSIGINGFLRPAHLLSGGA
                     TGIATSINYLTNINVGLLTFLINIPIFILGFIYLEKEFCISSLVNMIVFSLLLGATQE
                     ISNIIPIHDILLQSVYGGILSGLGVGVVFRTRSSQGGTDIIAAILKIKKNIEMKDTAL
                     AINGLIVLTGSFLFGLDLALYTLIGLFLNAYSMSFIKDAMNYQKSVMVMSNEVDLIAE
                     DIMKSLVRGVTFLDAEGAYTHQKKKIIYTIVSSNEIPKIKDIALKYDKKAFISVNDVT
                     EVKGRGFKAKDL"
     gene            6591..7400
                     /locus_tag="JAM15_09205"
     CDS             6591..7400
                     /locus_tag="JAM15_09205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798426.1"
                     /translation="MNLSKEYVNLYDNYLKYINEVNKEIRSIKNMKKRVLKKGDFAPE
                     NEVLELEGKTIRDIDDVDTKKPKNKIYKFSNGDVYVGKFLEGKMEGQGSYTFFVDEGT
                     AMEYIGEFKEDKKNGKGNFVFSNGNEYIGHFEEDMMNGIGNMLYNSKDEYIGTWKNGK
                     KDGKGIYKWSDGCIYAGEFKGGKMEGYGICYNSKGEVLYEGEWKNNLIHGKGTYIWEK
                     GKKYIGEFMHGKKHGQGTFYLNNELVYEGTWKFDKPSIFDRTLDEIFSLRL"
     gene            7543..8607
                     /locus_tag="JAM15_09210"
     CDS             7543..8607
                     /locus_tag="JAM15_09210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAT6798427.1"
                     /translation="MKRLIALVLVILIVLFYSPELIEEGYDLKEKFFQSEIWNEFLDK
                     ININNNSKKDKKEQNQNLQSNNTEGENLGESDIKNFEKISLGDNLSYVLSSIGKPGRI
                     DISEYGFDWYVYNQYGKEFAMVGLENDEVVALYSNSINSCENQDIKLNQDRQTVRTKI
                     TPLKYKRKGNTRYIINSENQYDIISKEGKYITIFYDIHEENRVCSYLIIDKSTEDEFK
                     KLYPDDREELKKCFELEVIDLVNSVRNQRGLNSLRYSEQATLSSRKHSEDMRDNNFFD
                     HINKKNETPFDRMKREGIVYTSAGENIAAGQINAIYAHEAWMNSEGHRKNILGNYNNI
                     GVGVIFGGSYKTYYTQNFYK"
     gene            8635..9354
                     /locus_tag="JAM15_09215"
     CDS             8635..9354
                     /locus_tag="JAM15_09215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HAT6798428.1"
                     /translation="MTSWKKKTVYKCLIAVVLFCGIVLISNFSKVSALMMDTNGNVLI
                     KHGSREKKLIAITFDDGPHPKETSQVLDVLKKYNVKATFFIAGKHAKWYKEPLVRASK
                     EGHEIGNHTFNHPDISNLSSSQIEEEIVKCEDILKEVTGKKPTLFRPPFGSYREKDLI
                     EIAKKHDYKVVLWTGVDVKDWKNPGANSIADKIINKVQNGDIILLHDYATNDTVEALD
                     MFIPKMIEKGFKFVTVSELIK"
     gene            9378..9962
                     /locus_tag="JAM15_09220"
     CDS             9378..9962
                     /locus_tag="JAM15_09220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HAT6798429.1"
                     /translation="MILMIDNYDSFVYNLVQYIEELGEAVVVKRNNEIKISDIEELNP
                     EVIVLSPGPCSPKEAGICIDIVEHFKGKKPILGICLGHQTIGHVFGGDIIKAQQPVHG
                     KVYSINHTNKGVFRGLKNPLNVTRYHSLIIDSNTVPKELEITAITDKGEIMGIRHKKY
                     LIEGVQFHPEAILSEYGHEMLENFITEARERVHM"
     gene            9964..11313
                     /gene="pabB"
                     /locus_tag="JAM15_09225"
     CDS             9964..11313
                     /gene="pabB"
                     /locus_tag="JAM15_09225"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HAT6798430.1"
                     /translation="MIREINTKLNSFEIFTIFRNEHDSFILDSAMDKEKLGRYSFISS
                     RPFKVLKYKDTDENPLEVLKEELHKYRVVNDTNLPFVGGAVGYLSYDLGNYIENLPRT
                     AVDDIEMPDMYFGFYNHVIVIDHLVQKTYIATPNIDIELEEKIIDDIEQRILKEEKKG
                     IDSICYEEKEVTPIRLKSNFTKEEFKNAVQSVREYIRQGDIYQANLTQRFSGETELTS
                     FELYRDLRRFSPAPFGAFLNFEDTHILSNSPERFIRCVNKRIETRPIKGTRPRGKDKE
                     EDLRLQQELRNSEKDRAELLMIVDLERNDIGRISKTGSVKVPELFVIEPYANVNHLVS
                     TVVGELKDDKDATDVIKATFPGGSITGAPKIRAMEIIDELEPTQRNVYTGSIGYIGFN
                     GDMDFNIAIRTIIKNDKKVYFQVGGGMTWDSDPDEEYQETLDKAKSIMKALRGYYEE"
     gene            11303..12046
                     /locus_tag="JAM15_09230"
     CDS             11303..12046
                     /locus_tag="JAM15_09230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate lyase"
                     /protein_id="HAT6798431.1"
                     /translation="MKNNVGFDSSLSKFGIGLFETIRVKNGIAVDLDIHIERMLSSIN
                     CLDLDINYKKDFLINEIVTYIKKENVINKALRITVFDEGYNISIRDIPYNQETYEKGF
                     KLAISPIVRGNSLIHRHKTTNYFENIYTKNIANKTGYNDGIFLNSEGVILECSMSNIF
                     FIKGERVYTPSDRLPILNGIIKKRIIEICDELHIELIENEINISEISSFDFVFVTNSL
                     MGAIKVTEIDKIKFNKENVVFDKIVKLLE"
     gene            12080..12781
                     /locus_tag="JAM15_09235"
     CDS             12080..12781
                     /locus_tag="JAM15_09235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798432.1"
                     /translation="MIGCIYEVYNEEMTKIIENQNTLAVYLVGSSKDVDFTLYDVEIN
                     DIDVFVFVKEGEKQERILFKKKGIEFDVNYFSKDGVKKLLSNREYFFVKEMKDAKVLF
                     DRENISHIIKDISRDIYLEGPSKMSLEEKSFIKQDIGAKISNLKNKEKFDVFEYHFLT
                     NLYLKDIIIGYFNINDKWVPKDKKLLKVLKKENNELFELVSKVSENYDYQRLLDVYNY
                     IFKEIETKEVIKLIF"
     gene            12807..13379
                     /gene="folE"
                     /locus_tag="JAM15_09240"
     CDS             12807..13379
                     /gene="folE"
                     /locus_tag="JAM15_09240"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HAT6798433.1"
                     /translation="MNKVDKEKIQHAVREILEAIGEDPDREGLIETPNRVARMYEEIF
                     SGLSEEPRDHLKVLFADEKHEELVLVKDIPFYSCCEHHLVPFFGKAHIAYLPKGGRLT
                     GLSKLARVIDTLAKRPQLQERITKNAADIIMEELQPYGVLVVVEAEHMCMTMRGVKKP
                     GSKTVTSAVRGIFEKDIASRAEAMSLITMK"
     gene            13445..14236
                     /gene="folP"
                     /locus_tag="JAM15_09245"
     CDS             13445..14236
                     /gene="folP"
                     /locus_tag="JAM15_09245"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HAT6798434.1"
                     /translation="MFDYGKRTYIMGILNVTPDSFSDGGDFNNLDIAIQHAKDMVDQG
                     ADIIDLGGESTRPGHSYVDSDEELRRVIPVIKKLKQELEIPISIDTYKADVAEEALKL
                     GVTMVNDVWGLRKDKNMASVIGKYDAEVCIMHNQDGTNYDKDIMESIKDFFKVSIEMA
                     MSCGVKKEKIVLDPGVGFGKDFEQNIEVLRRLNELKDLGYPILLGTSRKSVIGKVLPV
                     EPKKRLEGTIATTVLGIRDGVDIVRVHDVYENLMAARMTDAIYRK"
     gene            14247..14612
                     /gene="folB"
                     /locus_tag="JAM15_09250"
     CDS             14247..14612
                     /gene="folB"
                     /locus_tag="JAM15_09250"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HAT6798435.1"
                     /translation="MDKILLSNLGFYGYHGVLKEENFLGQKFFVDMELYIDSREAGLS
                     DDINKSVSYAEVYNVVKDITENKQFNLLEALAENIAEEVLNKFILINGVMVRVRKPEA
                     PVNGIYDYFGVEIRRTRDE"
     gene            14605..15111
                     /gene="folK"
                     /locus_tag="JAM15_09255"
     CDS             14605..15111
                     /gene="folK"
                     /locus_tag="JAM15_09255"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HAT6798436.1"
                     /translation="MNKAYLGIGTNMGDRFDNLSRACELLKNSDSIYKVKESSLYETK
                     PWGYTEQADFLNMCVEIETEFEPYELLEYCQEIERELHRERIVHWGPRTIDVDILFFN
                     DVVSTDEKLTIPHPRIQDRAFVLIPLMDLNEELIINEKTVKEHLNLLSAEEREEVKEL
                     VGYERKPI"
     gene            15092..15877
                     /gene="aroF"
                     /locus_tag="JAM15_09260"
     CDS             15092..15877
                     /gene="aroF"
                     /locus_tag="JAM15_09260"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HAT6798437.1"
                     /translation="MKENLFNNNSKIEINTNNKKITVKKDKLIIAGPCAIESYEQLLE
                     TAKFVKSQGANILRGGAYKPRTSPNSFQGLKKEGLEILKAVKDEVGMAVITELMDVRD
                     MDELYSISDIIQIGSRNMQNFTLLSEVGKQNKPVMLKRGIASTITEWIGASEYIAIEG
                     NSNIIMCERGIRTYNDYTRNTLDLAAVPIIQKETGLPVVVDPSHATGVRYLVKPMSLA
                     SFACGADGIMVEVHPDPENALSDGAQSLCFNEFEDLMRSINNY"
     gene            16132..17922
                     /locus_tag="JAM15_09265"
     CDS             16132..17922
                     /locus_tag="JAM15_09265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HAT6798438.1"
                     /translation="MNDIKDIIEEIKARCDIASIISEYMNIKQSGANYKGLCPFHGEK
                     TPSFYINTSKQIYKCFGCGEGGDVINFVMKMENLDFMDAVKILANKCGIEINTNMNEE
                     TRIKIEKSKKFQDIHTEAARFYLSNLLGSKNLGYEYLRIRGLDDKIIKKFGLGFSLDS
                     WNSLMNTLISKGYKKQDLLDCGLIAKNRDGTNCYDKFRNRVMFPIFDYRGNIIGFGGR
                     VLDDSLPKYLNSPDTLIFNKKQNLYGLNFARKNLESKTIVLVEGYMDLISLYQYGIKN
                     VVATLGTALTEQQGILIKRYADTAIISYDSDEAGIKATLRAIDILTKLGINVKVLDLK
                     DAKDPDEFVRKYGLSDYKKAMDVSTHYIKYKIDHLKKEFNIQKDEERVKFAKEASKII
                     KQLTSPVEIDFYTKYLSNQIDINVESIKREVYGKNYNKPYNNKNQKKIEEKVIEKVEV
                     RQDGKQLVEETLIKIMLEDKKIREIALLKVEESDFLLKESKEILNYMIKNQELDKITI
                     DKLKSLNISEEYLKELNSISLNSINLENTKEIEGIITNIRKNSLEEQINSLLREQQEL
                     ENNNDMKEVDGRVMEIALKIVEINKILKSL"
     gene            17940..19106
                     /gene="rpoD"
                     /locus_tag="JAM15_09270"
     CDS             17940..19106
                     /gene="rpoD"
                     /locus_tag="JAM15_09270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HAT6798439.1"
                     /translation="MENKSNKKELKKVTAKTLIEKGKKQGSLTLAEIMEAFSETELDK
                     DQVENLYETLGNLGIEITETKNYKADIDFSVADDDLSIGHLDEDAEAISHDDSSAIEI
                     ETVDLSLPKGISIDDPVRMYLKEIGKIPLLKPHEEVEFARRMHEGDEIAKQRLVEANL
                     RLVVSIAKRYVGRGMLFLDLIQEGNLGLIKAVEKFDYTKGYKFSTYATWWIRQAITRA
                     IADQARTIRIPVHMVETINKLIRVSRQLLQELGRDPKPEEIAKEMEMTEDKVREIMKI
                     AQDPVSLETPIGEEEDSHLGDFIPDDDAPAPAEAAAYSLLKEQIEDVLGSLNDREQKV
                     LKLRFGLEDGRARTLEEVGKEFDVTRERIRQIEAKALRKLRHPSRSKKLRDYLD"
     gene            19271..19960
                     /locus_tag="JAM15_09275"
     CDS             19271..19960
                     /locus_tag="JAM15_09275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HAT6798440.1"
                     /translation="MKLTDRLLKIASLVSDGKKIADIGTDHGYIPVYLLKEGKVPFAV
                     LADVNKGPLDNAHKEVIQNNLLDKVDLRLGSGIEILEIGEVEEVIIAGMGGILISELL
                     EAKKEVAHNVEKLILQPMQAQEELRYYLLNNGYEILKEVLVREDFRIYEIIVAKYTGK
                     NTIIEDEIYYEVGIKLLENKDSLFNDFIEKKIKTYSSIVNKLEGKNGEAIDKKRKESE
                     VAIKKLENLIK"
     gene            19974..21071
                     /locus_tag="JAM15_09280"
     CDS             19974..21071
                     /locus_tag="JAM15_09280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HAT6798441.1"
                     /translation="MLLKSLTGKIEKKYPLNLAEDWDNVGLIVGDFDMDVKKVLVSLE
                     ANEDVIDEAISKNIDLIVTHHPFIFGKINKINSGDLKGRLIQKLIKNDISLYSMHTNF
                     DIAFDGLNDYFMEIMEFGNSKVLDITKSENLYKLAVYVPHNYSDELRKVLSNSGAGHI
                     GNYSDCTFSIEGEGQFKPLEGSNPFLGSVNDIETVNEVKIETVVPQKLLGGVINSMLD
                     AHPYEEVAYDLYKLENKGEIFGLGRISKLDKSMTLESLSRKIKEKLNMKHIRVVGNLS
                     TDITKVAVVTGAGSEFVKKAKRQGAEVLITGDVKYHEAQDALDIGMCIVDCGHFDTED
                     IFKNVMKRFLDEFSEIEVIKSNVYLNPFSTI"
     gene            21133..21705
                     /locus_tag="JAM15_09285"
     CDS             21133..21705
                     /locus_tag="JAM15_09285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HAT6798442.1"
                     /translation="MKVAVIFHSVCGSTYLLAREYKEVLEEMNIEVDIFRVSDEVAKT
                     LPQYYLINSKEYKDEFESINVIKSGKEILDYDAIFMGSPTYYGNVSGPMKMFMDSFSD
                     IWVGAPLSGKIFGCFATAGSQHGGGELALQAMNIFAQHMGMTLLSVPCSVRGGYPAYG
                     ILHIAGDNSDIRPNDDAKIGIRDYLKRLNI"
     gene            complement(21765..22232)
                     /locus_tag="JAM15_09290"
     CDS             complement(21765..22232)
                     /locus_tag="JAM15_09290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HAT6798443.1"
                     /translation="MFKEMRLKKREMTKEDTVEVLKNGEFGTFSTISENGYPYGVAVN
                     YVYFNDSIYFHCARNGHKLDNISKNNKVSFLVVANESVIPDKFSTTYSSAIVFGKACT
                     VENEEKKNALVEIIKKYSKGFFEEGMKYIEKDMNLTTVVKIEIDHISGKASRL"
     gene            complement(22618..23094)
                     /locus_tag="JAM15_09295"
     CDS             complement(22618..23094)
                     /locus_tag="JAM15_09295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAT6798444.1"
                     /translation="MLSKAEIKYFNECASEILSSEKVQLMRTFPHHGNVSCLEHSLSV
                     AYYSYLLCKKLHLSVDIQSVIRGALLHDFFLYDWHYKGDRKGLHGFTHPREALKNATL
                     FFQINEKETDIILKHMWPLTVKPPRYKEAFIVCLLDKFCCLAETLKIHSLLSPYHV"
     gene            complement(23214..24305)
                     /locus_tag="JAM15_09300"
     CDS             complement(23214..24305)
                     /locus_tag="JAM15_09300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1648 domain-containing protein"
                     /protein_id="HAT6798445.1"
                     /translation="MSKIECLFTIFPVLILMYATFYFMPYFVGKKHIYGVSIDQEHKN
                     YNYFIKLDKEFKKLLSLGFIIDFILVFILVFTFNKLELSYFIGIIGFLLYESILYIHT
                     HKKAKKLKSEIYSKLGHIDVDSKLIVDMDFINKKNKIIKKFKIIYLIPILFTLGMSIF
                     IAFNYNQLPDSIATHWNINGSPDVFIDKSFLNVFKLIGTDFCLMVLLYITSIGSIKSR
                     IKIDTNRIEESRVENIKYLNKIGYLFLILMIIMTTQFFTTLLSIKTKLSTAMNITTLL
                     VIIYLIATYINSPNLKFNSSYSPEEDEKYWIAGIMYNNPNDPSLMVNKRFGIGWTINF
                     GNPLGKILYIAIALLLIFSLFSLIKSLLL"
     gene            complement(24298..24687)
                     /locus_tag="JAM15_09305"
     CDS             complement(24298..24687)
                     /locus_tag="JAM15_09305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAT6798446.1"
                     /translation="MVLNLDFNSDKSIYVQIKEEITKAIASGELKINESLPSVRSMAE
                     NIGVNLHTVNKSYNELKEEGFLNIDRRKGAIVAQLPMKIDNTTRQKNKLDLELLVAKS
                     YLSGISKEEFLSLSSSLFDKYEVKYYE"
     gene            24879..25325
                     /locus_tag="JAM15_09310"
     CDS             24879..25325
                     /locus_tag="JAM15_09310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798447.1"
                     /translation="MLTYLMKRQMHKKDDGMSKPMMITGAVLTGVGAYAVYKMVKSHK
                     SNSQMVDTNYYGNSDYDDYKYDEFDYDCDCRDTKQDYEYEELKKKVKEFNSRRINCEN
                     CPHVSQEEMMQYVNSVKDVKEEIDLHEDAKKDNIYKEDEYKKYEEE"
     gene            25615..26319
                     /locus_tag="JAM15_09315"
     CDS             25615..26319
                     /locus_tag="JAM15_09315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6798448.1"
                     /translation="MLKLLLVEDDSTISFGIKYALEQEGFSIDISKDLSSGKEMISSN
                     EYSMILLDVTLPDGTGYELCQYIRGFSQVPIIFLTACDEEVNIVMGLDIGGDDYITKP
                     FRIRELISRIKAVLRRKGNTLEESKKILKFGDLSIYTLEARVYKNDKEIFLTSVEYKL
                     LLILIQNKNTVLSRTQILEKLWDVTYDFVNDNTLTVYIKRLREKIGDDLCEPIYIETV
                     RGIGYKWIGSENSVSI"
     gene            26306..27550
                     /locus_tag="JAM15_09320"
     CDS             26306..27550
                     /locus_tag="JAM15_09320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAT6798449.1"
                     /translation="MFLYNPEVKKFLSKYVTLMFIVIIISIGFSIINVSLTKEMVVRN
                     NQAIIGTLSSKYPNLESQIVDIITQGKSMKNIDYGQKILSKYNYDKSIKINSEPIISK
                     LVLETIKINIILVCIIFILIFVLVVRYFTSIYNDLSDMTKYVYYSSEGKPFDMKNKNQ
                     EGQIGLLKTELLKMTTILNEKVELLKREKIFLNNTISDISHQLKTPMTSLIMLNDLLY
                     NDVPYEVKIDFLNKIKNQLNRMDWLIKSMLKLSKVEAKVINFKKDKVKFSELIHRAML
                     SMKIPMEIKNQKLTIEGNDNVSYIGDIDWSVEALVNIIKNCVEHTPEFGNIIITYKEN
                     PLFSELIIKDEGEGIDKKDIPHVFKRFYRGRSSSKEDSVGIGLAMSKSIIESQNGDIY
                     VNSEKGKGTEFHIIFHKMYDSD"
     gene            27630..28307
                     /locus_tag="JAM15_09325"
     CDS             27630..28307
                     /locus_tag="JAM15_09325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6798450.1"
                     /translation="MEILRVENLTKSYGKNETKVDAIKNVSLSVEKGTFIAITGPSGS
                     GKSTLLHLLGGVDRPTSGKVYINDVDIYNLKTKDLAIFRRRNIGLIYQFYNLIPVLNV
                     KENILLPAELDNRDIDREYFDDLMKTLGLIDREKHLPNQLSGGQQQRTSIGRALINRP
                     SIILADEPTGNLDSKNSKEILELLKLSVKKYNQTLIMITHDKNMALQADRIISIEDGI
                     IKSDEVM"
     gene            28308..30869
                     /locus_tag="JAM15_09330"
     CDS             28308..30869
                     /locus_tag="JAM15_09330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6798451.1"
                     /translation="MNLYTSLTIRYLKQNKRRTIVTIIGIILSTALICGIGNIFESFM
                     DYQMRETIKNDGSFHVTFYDVNRKNVEYVTKSAEIEKHAFTKQLGYSKLENSENAILS
                     IKQYDKNAINGYKVSIKEGRFPAKEGEIVLSESIINLIDDKLKIGDKITLKVGDMFDS
                     SKKKIDSMTFHEGDYIANEKDRTFKVVGIIKKPGFERYNGIATAIAYFNPMNNYNDTI
                     NVSVAVRNPKDVYKISNKISKNIYSNKDKEAVSDMIKYNEHLLRLQGASKYSNINSSI
                     KSIIIAVTILVIICTIATVYNSFSISINERKKQFGILNSIGATSSQIKRFVFIEGIII
                     SLIGIPIGLISGTVAIDLLFKIINKYFTESVVTKMSLQIVYNPIIIIVSIIIVLLTIF
                     ISILLPAISASNISPLNVIKNTGEYKVGKIKSSRLIKMIFKTEGILAYKNIRRNRKKF
                     IVTLFSLMVSIIIFISFSGFTLLLLRSEEIRNSQRKYDLYLTAKNTARSVEDTISELE
                     GIDGIKNFELATGQYVSIRVSENKINKSKEDLIRKYYQKYKIGDSYEYDFSNNELIFP
                     GDFAVKNKINNLVQGSFNKERAIEENGVILVRKSAFEENGKKGVVELTNYKVGDTVNC
                     EYLDENALSKKVKVKILAITDEERLGFGYQNMGLQFITYDEVAKNLNLKLSKSLIFID
                     SGGSVKTKKEIEALANKNNFNFYDEISSSESEKQDLKVIKIFVYGFIVVISLVSVTNI
                     LNTVSTSINLRKRELAVIQSIGVTPKGFRKMIYLESFIYGILSLLFGIPISIGIILIM
                     NKLISGVIEFSPIIPWTAIVICIVSVFIITFIAGYIPMSKLNKENIIDNIRRESI"
     gene            31099..32364
                     /locus_tag="JAM15_09335"
     CDS             31099..32364
                     /locus_tag="JAM15_09335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010075481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HAT6798452.1"
                     /translation="MSHITAKNMYKSLEERINKFPQGAPPSDTLYKILNVLYTEQEAK
                     LVAQLPIKPFRVKTAAKIWSVSESEAYRVLDKLASKALILDIEDNKGKKYIMPPPMAG
                     FFEFAMMRTRHDIDQKLLAELYYQYMNVEEDFIKDLFYSTETKLGRVYVQEEVLTNDN
                     EVSILDYERATHIIDESTHIGISMCYCRHRMQHVGKACDAPMDICMTFDNVANSLINN
                     KFARRVDKIECKELLHQAYEHNLVQCGENVRKGVTFICNCCGCCCEAMVAAKRFGNLH
                     PVQTTSFIPNINHENCVKCGKCITACPIDAISKVKEGDKEYIKIDEDRCLGCGVCVRN
                     CHKNSIMLLKRDEKIITPANSVHRAVLMAIEKGQLQNLIFDNNALASHRAMGAILSAI
                     LKLEPAKKILASKQLKSVYLDKLLSMNDK"
     gene            complement(32525..35566)
                     /locus_tag="JAM15_09340"
     CDS             complement(32525..35566)
                     /locus_tag="JAM15_09340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp20"
                     /protein_id="HAT6798453.1"
                     /translation="MFKQRISKLLSSTLVLSMLFTAAPNITFADNTKDNSEKYQSSDI
                     ELHDYSKNAESYTKTKALAKEKIQTLLSKYGAVSAQYALIDNGKIEISGNGGVYSKQD
                     NKNLNKDNMYSIASISKMFTTTAVMKLVDDGKLNLDTPVVKYIPEFKMADDRYKEITP
                     RMLLNHSSGLMGSSFKNTILLADNDSYGHDNFLKELQKQRLKAKPGAFSVYCNDGFTL
                     AEILVERVSGMSFTNFLDKYINNPLNLQNTKTTENSFDSSKLAKAYVPYWEDAVPQDN
                     LNAIGAGGLYSSAENLCTFAQTFMKNSNGILSPASVKAMENKEYLNGLWPEGEDSILG
                     YGLGWDCVNTYPFNQYNLKALTKGGDSLLFHSNLIVLPDENMAVAVLSSGGSSQLNEI
                     IGQEILLSALKEKGKIKEIKPDKTFSKPQQVKMPSSLKENSGLYASSNMIKVDVNDNG
                     TLTVSSPYIENGPEDKYVYIGQDRFVSEKGNSCLKFVKEKNNITYLNMSSYDDVPGLG
                     QTASLYYVAQKVDDNNISNSVKEVWKKRSGKGYYLVDEKYTSQSYMFGSVKASFSLSD
                     ETPGYIVNTKIMDENNSNAFIEIPGVIGRDLSDIKLHKENGTEYLSFGTLTYVSEDSI
                     TNLPAEKSFTCELESNGYAKWYKIGDDIANKKIEVNLPQNSAFAVYDDKGVPVNYSLV
                     TKNNRVRLPKGGVIVFLGSPNARFEVTYQDEVNASALTGTDRYETSIKISQAGWENAE
                     NAVLINDSAIADALAATPFAYKKNAPILLTGSSQINEKTLAELKRLKVKNVYVVGGEA
                     SINEKSLDTIKSNNISVSRISGSDRYQTSMNIAKELNNISNISKISVVNGEKGLADAV
                     SIGAVSAQNDMPIILTNENSNITEINNLFKNKKIDKSYVIGGEYTVSKNIENKLQNPQ
                     RISGSTRNETNAKVIKEFYKDSKIDNLYVAKNGMNKQDDLIDGLSVGVLAGKTKSPVM
                     LVGNSLDYNQKELFKTMRFKSVTQIGGNGNENSFKQIKEIA"
     gene            35773..36072
                     /locus_tag="JAM15_09345"
     CDS             35773..36072
                     /locus_tag="JAM15_09345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAT6798454.1"
                     /translation="MYKNINKKQLKEMMKNEKDVLLLDVRTKDEFKEYKIENAINISL
                     QDLINNIDEIYDYKDKKVVVYCRSGHRSVTACNLLAEEGFEHLYNLNSGIIDYMS"
     gene            complement(36310..38529)
                     /locus_tag="JAM15_09350"
     CDS             complement(36310..38529)
                     /locus_tag="JAM15_09350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HAT6798455.1"
                     /translation="MKKTNSLKEILNWNNIKNLRPSKGLKNILEIFKSDLKDIRGNYA
                     VLVIVLGLAFLPSLYAWFNIKASWDPYGSTANMLVAVTNEDKGNEIAGQKINVGDQLI
                     EQLKDNKSLGWQFVDEKTALEGVKKGTYYASLKIPKNFTKDLTSLITDDVKKGEIIYT
                     VNEKINAVAPKITDKGASTIQLQVNQTIVKTVSEIVLGISNGVGAGIEHSLPKLTKVE
                     NSLIDLQKRFDHINKTVDLASDATSKLSDTVKDIKSDLPTIKKTLNDTKLLSSDLKKF
                     LEDTNDNLDELSPLIKSDLNLMVDLSSSASSLTLNLIDAVNSGSEDVPKLIDNLSEKL
                     SNLQSLNDTLVDFLTKLNQLTSNNRLDDVIDNLEDSSNKIDSSISTLNDIKNKVISGQ
                     QPSISALNNVLSLSNGIGRINLNILNNFDSKISKPINSIFANSIKVANDIITVLDKAE
                     AKLPKVEEILTTSLKLSGNAQESISLIRERLPLAKGMLDDLIDTLSKISNGEDMKKLV
                     SLLESDILTKSNFLKEPVEVKTEKLYPIENYGSAMTPFYSVLSTWVGILLISALLSTS
                     VHGNYKPYEIYFGRGLTFLSIALVQGFIIGTGDILLLGVTAKHPILLIVLLMFTSMVF
                     NFIVYSLVSVFGNVGKAIAIVLLVVQIGSSGGTFPIQVTPTFFQRINPIMPFTYAIGA
                     TREAVGGIYAPNLTKDILVLLLFMILSICLNVLLKGPINRVIKPFNDKFGDSNLTGH"
BASE COUNT        15457 a         4186 c         6494 g        12500 t
ORIGIN      
        1 ttttaaggcg cattatgtag taatataata atagggatat ataaataatt ttattgtaag
       61 gagaagtatg ggatgagtaa tgtgaacaaa aagctagtta tagctattgg agctgtagca
      121 ttagtagcaa taatttttat aggcataatg tgcatgcaat ttaaagggga gaaaatagca
      181 aaaaacacat atgttaatgg agtagatatt ggaaaattaa ctaaatcgca agcaaaacag
      241 gaattagcta aaaaatacaa attagagaat gttgagttta attacaatga taaaagttgg
      301 aaagtaaaga gcaaagattt aaatttatct actgatctgg ataaaacagt agaaaacgca
      361 tataatttaa atagaaagag tagtttcttt ggcaatctat caaaaactat ttcaacaaat
      421 tttggcaaaa aaagcaactt agtagttgtg ataaattatg ataaaaataa attaaaagca
      481 gaaatggaaa aaatagctaa agaaatagat gtagatgtaa aagatgctac acttgatata
      541 agtggtgaaa aagtcaaggt tataccagat tctgatggtc ttaaaatgga tatttctaag
      601 agtatggaga attttgataa tcaaactaaa aaaggtaact ataaaaatga gttagtagta
      661 aaagctactc cagcaaaagt aaaaaaagag caacttgcta atatagatac aaatttaggt
      721 acgtattcaa caatatttaa aacttctcaa ataaatagaa gtataaacat aaaattagca
      781 acagataata taagtaatgt attacttatg ccaggagaaa ctttctcatt taataaacat
      841 acagggaaaa gaagtaagga aaatggatat aaaagtgcac ctgtaataat ggaaggtgag
      901 atggaagaag attatggtgg aggagtttgt caagtttcat ctacgttata caattctgtg
      961 ttatacgcag gtttagaaat tgttaatgta aaaaatcata ctataccatc aagttatgtt
     1021 ccaaaaggaa gagatgcaac tgttgcagat agtggaatag atttcttatt taaaaataat
     1081 ctaaagcatc cagtttacat aaaaaattac gtttcaggaa atcaaattgt ttgcaatata
     1141 tatggaagtg cagaagataa acaaaatata acgatatcaa caaaattaga tggcgtttca
     1201 caaactacaa tgaaaagagt taatgaccct acaatgccta aaggtaaaga aaaagtagac
     1261 aaaagtggaa gaaatgcata ttctgtatca acatatagaa catttaatga tgcaaatggt
     1321 aaaaaaatta aaactgaaaa aatagctaat tcatattatc ctaagaagga aggtattata
     1381 ttagttggga ctatggaacc aaaaccagag gaaaaaccaa atacagacga aaataagaat
     1441 aatcaaaata caaacaatca aaatccaaat aatcaacaaa aaccagaaac accaccaact
     1501 gataataagc ctaatgagac acaaccacaa ccgcaagctt aaagttctca agaataggat
     1561 ttatgtagag taataaaaaa tataaatcta aataggaggg attactttga atttaaataa
     1621 tataacgaat tacgttcaaa gtatttgcga gaatatttct aatgtcttgg atgtagatgt
     1681 tactttagtt acaaaagatt taactaggat agcaggtaca ggaatattca gaggtaaaat
     1741 aggagagaca atatcagaga agtcagtgta ctctcttgtt ttaaaagatg gaaaatccta
     1801 tgttataaat aaagaaatag aagagaactg taataaatgt gcaaatagag aaaattgtaa
     1861 agagttagct gatatatgta ctcccgttaa aatgggagag catatacttg gaatcttggg
     1921 tatagctgcg tttaatgaag aacaaaaaga aaagatactt tcaaaagata aggagttaac
     1981 tgcttttgta aggagtatgt ctgatttaat atcttttaaa ctagatgaac tttataaaca
     2041 agaagttaag actatagatg accttgagag ggaagctata gaaaatgcca taaagaaata
     2101 tggaagtaat acagaaggta tgaaaaaagt agctgaggca ttaaatatag gtatagctac
     2161 actctataga aaagtaaaaa aattcaacat taaaagttaa tagtattgaa aaagaggtaa
     2221 cctttttatg aaaagaagag gattaccttt tttattatga gaatggtgga aaaatatgta
     2281 tagttttgac ttgacatatt aaatatgtta tcttaaatat atattttaga gtggaggtga
     2341 gtattatttt agttaaagat ataaaacaag acatagaaag catgcctaga aaaattttag
     2401 atatatcttt gatagaagat aataaaagtg atttgacttt ttttaatata gaagaagaag
     2461 acggtgatga aacattaaaa gcattaaaac agagttatgt gactacaaat tataaagaag
     2521 aaactctatt aaacttgcaa ggagctttaa attcaaagtc agacacaacg tctaaggagt
     2581 taaaattaga atcatataaa agatataaca atgcattgga tttagcatat aaaaattata
     2641 taactagtgc cattaatatg gttaataaag ctctggagat aaatcctaaa gacattgata
     2701 tactaaatct tagaggtctt ttaaaattat taaaatgtga ttttgctaaa tcatttgaga
     2761 gtttttatac tgctttatgt tatgagaata atcatatatc tagaaaatat gtaaatctaa
     2821 tttcatctga agattttaaa acttttttag gaagatacaa tcattctata agatttataa
     2881 atgaagaatt aaattatgag tcaatacata ttttagagaa cataattgaa gaagaacctg
     2941 aactaataga gccatatgta attttatctt tgttatatga taaactaggt aatgtaaaaa
     3001 agagagaagg atatttagac aaacttaaag agctagataa agataatcct gtatttgaaa
     3061 aaaatgaaga agaaaaagaa gatacaagta aaaaggaaga aataaaaaaa gtaaaaagaa
     3121 agaaaagtat tttaccatat attatagttg gctgtgtttt aataggtatg gggatatatt
     3181 tgattcaaag caaaaagaga atagaaaact tgaataacca aataagtagt aaagaggaaa
     3241 agttaagtga aactgataaa aagttaggag aaacgagtaa aaaattagaa aaaacgaata
     3301 aggaattaaa tgaggttaaa aataaagaac cagaaagaga gataactgta gctgatgagg
     3361 aagatttata ttatcaagct ctaaatttaa agaaaaacaa agaatatgaa aaagccatag
     3421 ataattttaa aagtgtagtt tcttctggta aaactaaaaa atatatttct gagtcaatat
     3481 atcaattagc aataacaaat aaattattag gaaataagga tgaagctata aaatattaca
     3541 aaaaatatat aaatacttat actaaaaatg accagtatta tgatgattca tattacgagt
     3601 tgggtatgct ttattatgat aatggcgatt taaaaaatgc acaacagact ttttatagtt
     3661 tgagaagtga agttccagac agtatgtata acaattcaaa aataaaagaa atcttaagtg
     3721 aaaaataggt ttatatagtt aagttttttg aaacaaccaa gtatgtattt tattaaatta
     3781 aaataaaaat aaatttaaaa agagattgtg tcaaattata actttctatt ttaaagaaag
     3841 atatttgctt gttgataaaa ctacaaatat atgatttgaa gcaatctctt taatttttgg
     3901 aggtggaaaa tgaaagtttt caatcaatta gtaataattt tatctatctg ggtaatagga
     3961 gagtatataa gttcctttat acaaggaatt atacttattc ctgggagtat agttggtatg
     4021 ctattattat ttctactact acaatttaaa gttttagact tgagtagtat agaaaatgta
     4081 agtggatttt tcctcgataa tatggctata ttttttattc cagcaggtgt atcacttata
     4141 aagtcattag acctaataag ggaaaatgta ttagtgcttt tattagtcat atgtttaagt
     4201 acactaatag taatgtatac tactggaatt attgtggaga aaatgataaa aaagaaggaa
     4261 gaaggacaaa aaaatgtata atgtattaca gacaccagta tttggtataa tagtaacaat
     4321 agtttttttc aatttaggaa gatacattca acgaaaaaca agtaatccta tatgtaaccc
     4381 tttattaatt gcaatcgtag gaataatatt gtttttaagc atatctaaaa tcccttatga
     4441 gaattacaag ataggagctg atagtctaaa tttcttttta ggtcctgtca cagtagtact
     4501 tgcagttcca ctttataaac aatttgaatt atttaaaaag catatgtttg agattattgt
     4561 aggaataggt tgtggtatag tgatttcttt tgtatctgta ttgataattg gcaaaatagc
     4621 taattcagat gtaagtataa taaattcact aattccaaaa tctataacaa caccaatggg
     4681 aatatcttta gcaaattctt taaatggtat agaatcaata acagttgtag ccataatttt
     4741 tacaggtatt tttggtggta tggttgcttc tacagtattc aaactgggga atataaatca
     4801 tccagttgct aaaggaattg ctcttggaac atctgcacat gctttaggaa ctacaaaagc
     4861 ttttgaactt ggagaaatag aaggagctat gagtggtgtt tctattggag tttctggtac
     4921 aattacagta atactaattc caattataat gaattttata taaaaaataa aattaagacg
     4981 agtaccttga atacttaaaa caaaataaaa taaaaaaaat ttaaaataaa aactgaacga
     5041 aaaaaatgca aataatgaaa taaaaaaatc atgtactgaa attataaaaa gaaaaatttc
     5101 atttaggaat taattataaa gagataatta ctaaacttga atttgctaaa ataaaataaa
     5161 ttactgcgaa aatagatatt tagaaaaaaa tactataaat ttactatatt gcaagttaaa
     5221 taataagcag tatcatatta tgctagaaaa agtttcattt aaggcataaa tgagatgatt
     5281 tgaacgtttt taaagattag aatataaaag attgcactag acatatatga aaaagataat
     5341 ataatagatg atgtaataga tgacagttca agaaattata aaaaaaattt atttgaaata
     5401 ttatctatta catcaggaat aatatatgta agagtaagct tttaaaattc taaagattta
     5461 gaaagattga agggagaaag aaatgagtga agttaagaat accctacaaa aacatccagt
     5521 tttaagatat tcaacaatgc tatttgggat gttgatgaca tctataggaa taaatgggtt
     5581 cttaagacca gcacatctgc ttagtggagg tgctacaggt atagcaacat ctataaacta
     5641 tttgacaaat ataaatgtag gtttattaac atttttaatc aatattccaa tatttatctt
     5701 agggttcata taccttgaaa aagagttttg tatttcaagt ttggtaaata tgattgtatt
     5761 ttcattatta ttaggagcaa ctcaggaaat aagtaatatt atacctatac atgatatatt
     5821 gcttcaaagt gtatatggtg gtatattatc tggtttagga gtcggagttg tatttagaac
     5881 taggtcttct caaggtggta cagatataat agctgcaata ctaaaaatta agaagaatat
     5941 agaaatgaaa gacactgctt tagcaataaa tggcttgata gtacttacag gaagtttttt
     6001 atttgggttg gatttagcat tatacactct tataggtcta tttctaaatg cgtattcaat
     6061 gagttttatt aaagatgcaa tgaattacca aaaatctgtt atggtaatgt caaatgaagt
     6121 cgatttaata gcagaagata taatgaagag tttagttaga ggtgtaactt ttttagatgc
     6181 agaaggtgca tacactcatc aaaaaaagaa gattatatat acaatagttt catcaaatga
     6241 gataccaaag ataaaagata tagctttgaa gtatgataaa aaggccttta tatctgtaaa
     6301 tgatgttaca gaagtaaaag gaagagggtt taaagcaaaa gatttataga aaattttaca
     6361 agctgggagt ttataatgta aatttgtata ttatatctct cagcttattt aaatttagta
     6421 tatgaaaata aaggttttat caatgatttg tgtatcactt taaaagatat cattttaaaa
     6481 ttaaaattga aaaaattact caatatgtag aaaacataac cactattagg atataataaa
     6541 tttaatagat ttagtaaaat atctaggaat aacgttggag gaatagcatt atgaatttat
     6601 ctaaagaata tgttaatttg tatgataatt atttgaaata tataaatgaa gtaaacaaag
     6661 agattagaag tataaagaac atgaagaaac gtgttttaaa aaagggcgat tttgctccag
     6721 aaaatgaagt attagaattg gaaggaaaaa caatacgcga tatagatgat gtcgatacaa
     6781 aaaaaccaaa aaataaaata tataaatttt caaatgggga tgtgtatgta ggaaaatttt
     6841 tagaaggaaa gatggaaggg caaggatcat atactttttt tgttgatgaa ggaacggcta
     6901 tggagtacat aggagagttt aaagaagaca aaaaaaacgg aaaaggaaac tttgtatttt
     6961 caaatggaaa tgaatatata ggccattttg aggaagatat gatgaacggt attggaaata
     7021 tgttatataa tagcaaagat gaatatattg gaacttggaa aaatggaaaa aaagatggaa
     7081 aaggtattta taagtggagt gatggatgta tatatgcagg tgaatttaaa ggtggaaaga
     7141 tggaagggta tggtatttgc tataatagta aaggggaagt actttatgaa ggagaatgga
     7201 agaataattt gattcatggt aaaggaactt atatatggga aaaaggtaaa aagtatatag
     7261 gtgaatttat gcatggtaaa aaacatggac aaggaacttt ttatctaaat aatgaattgg
     7321 tttatgaagg gacttggaaa tttgataagc catccatctt cgacagaaca ttagatgaaa
     7381 tattttcatt aagactatag ctttatctat taatagataa agcttttttc taatacttac
     7441 tgtaaataag tatgaatgat attgattagt atacactatc aatattaact caataaatgt
     7501 gatattaaaa atttttgatt gattttaaga aggagggata tattgaagag attaattgct
     7561 ttagtgttag taatacttat tgttttattt tatagccctg aattgataga agaaggatat
     7621 gatttaaaag aaaaattttt tcaaagtgaa atatggaatg aatttttaga caaaataaat
     7681 ataaataata attctaagaa agataaaaaa gaacaaaatc aaaatttaca atcaaataat
     7741 actgaagggg agaacttagg agagtcagat ataaagaatt ttgaaaaaat aagcttagga
     7801 gataatttaa gctatgtttt atcaagtatt ggtaaacctg gtagaattga tattagtgaa
     7861 tatggttttg attggtatgt atataatcaa tatggaaaag aatttgcaat ggtcggactt
     7921 gaaaatgatg aagtagtagc actttatagt aattctatta attcatgtga aaatcaagat
     7981 ataaaactaa atcaagatag acaaacagtg agaactaaga ttacaccatt aaaatataag
     8041 agaaaaggaa ataccagata tataataaac tcagaaaatc aatatgatat aataagtaaa
     8101 gaaggtaagt atattacaat tttctacgat attcatgaag aaaatagagt ttgctcatat
     8161 ttaataattg ataaaagtac tgaagatgag tttaaaaaat tatatccaga tgatagagaa
     8221 gaacttaaaa aatgttttga acttgaagtt atagaccttg taaatagtgt tagaaatcaa
     8281 agaggattaa actcattgag atacagtgaa caggcaactt tgagttcaag aaaacatagt
     8341 gaagatatga gagataataa tttttttgac catataaata agaagaatga aactccattt
     8401 gacagaatga aaagagaagg tatagtatat acttcagctg gagaaaacat agcagcagga
     8461 cagattaatg caatatatgc gcatgaagct tggatgaact ctgaaggaca tagaaaaaat
     8521 attttgggga actataataa tattggagtt ggagtaatat ttggaggaag ctataaaaca
     8581 tattacactc aaaattttta taaataacta aaatatttga aaggaagtta aaaaatgaca
     8641 tcatggaaaa aaaagacagt atataagtgc ttaatagcag tagtcttgtt ttgtggaata
     8701 gtgttaatat ctaattttag taaagtttct gctttgatga tggatactaa tggaaatgtt
     8761 ctgattaaac atggttcaag ggaaaaaaag ctaatagcaa ttacctttga tgatggtcct
     8821 catcctaaag aaactagtca agttttagat gtattaaaga aatacaatgt aaaagctact
     8881 ttttttatag ctggaaaaca tgcaaaatgg tataaagagc cattagtaag agcaagtaaa
     8941 gaaggtcacg agataggaaa tcatactttc aatcatcctg atataagtaa tttaagttct
     9001 agtcagatag aagaggagat tgttaagtgt gaagatattt tgaaagaagt aactggaaaa
     9061 aaacctacat tatttagacc accatttgga agttatagag aaaaagattt aatagaaatt
     9121 gcgaaaaagc atgactataa agttgtttta tggacaggtg tagatgtgaa agattggaaa
     9181 aatccaggag ctaatagcat tgcagataaa ataattaata aagtacaaaa tggagatata
     9241 atacttttgc atgattatgc aactaatgat acagttgaag ctttagatat gtttattcca
     9301 aaaatgattg aaaaaggttt taaatttgta acagtttctg agttgataaa ataattttta
     9361 ggggggagat ttacagtatg attcttatga tagacaatta tgattctttt gtatacaacc
     9421 tagtacaata tatagaagaa ttaggggaag cagttgtagt aaaaagaaat aatgaaatca
     9481 aaataagtga cattgaagaa ctaaatccag aggtaattgt gttatctcca ggaccgtgtt
     9541 ctccaaaaga agctggtatt tgcatagata ttgttgagca ttttaagggg aaaaaaccta
     9601 tactaggaat ttgtttaggt caccaaacta ttggacatgt ttttggagga gatattataa
     9661 aagcacaaca gcctgtgcat ggaaaagtat atagtatcaa ccatactaat aaaggagttt
     9721 ttaggggact taaaaatcct ttaaatgtca ctaggtatca ttcactaata attgattcca
     9781 atacagttcc aaaagaatta gaaattacag caattactga taaaggggaa ataatgggga
     9841 ttaggcataa gaaatattta atagaaggag tacagtttca tccagaagct attttgtcag
     9901 agtatggtca tgaaatgctt gaaaatttta taacagaagc tagagaaagg gtacatatgt
     9961 aatatgataa gagagataaa tactaaatta aattcttttg agatatttac tatttttaga
    10021 aatgaacatg acagttttat attagacagt gctatggata aagaaaaatt gggaagatat
    10081 tcttttataa gtagccgacc atttaaggta ttaaagtata aggatactga tgaaaatcct
    10141 ttagaagttt taaaagaaga actacataag tatagggttg taaatgatac taatcttcca
    10201 tttgtaggag gtgctgtggg atatttatct tatgatttag gtaattacat agaaaattta
    10261 cctagaactg ctgtagatga tattgagatg cctgatatgt attttggatt ttataatcat
    10321 gtaatagtta tagaccatct tgtgcaaaaa acttatatag ctactccaaa catagatatc
    10381 gaattagaag aaaagataat agatgatata gaacaaagaa tattaaaaga agagaaaaaa
    10441 ggtatagata gcatatgtta tgaagaaaaa gaagtaacac ctataagact taaatctaat
    10501 tttacaaagg aagaatttaa aaatgcagtt caaagtgtta gagagtacat aagacaagga
    10561 gatatatatc aagctaattt aacacaaagg ttcagtggag aaacagaact tacaagcttt
    10621 gaattgtata gggacttaag aagatttagc ccagcaccat ttggggcatt cttaaacttt
    10681 gaagatacac atatattatc aaattctcca gaaagattta taagatgtgt taataagaga
    10741 atagaaacta gaccaataaa aggtactcgt ccaagaggga aagataaaga agaagattta
    10801 agacttcaac aagaacttag aaatagtgaa aaagatagag ctgaactact tatgatagta
    10861 gatttagaaa gaaatgatat tggcagaata tctaaaactg gaagtgttaa agttccagag
    10921 ctatttgtaa ttgaaccata tgcaaatgta aatcacttag tttccacagt tgtaggtgag
    10981 ttaaaagatg ataaagatgc tactgatgta ataaaagcaa cttttccagg ggggtctata
    11041 acaggagcac ctaagattag agcaatggaa attatagacg aattagagcc aacgcaaaga
    11101 aatgtatata ctggttcaat aggttatata ggttttaatg gtgatatgga ttttaatata
    11161 gcaattagaa caataatcaa aaatgacaaa aaagtctatt ttcaagttgg aggaggaatg
    11221 acttgggatt ctgacccaga tgaagaatat caagaaacac ttgataaagc taaatccata
    11281 atgaaggctt tgaggggata ttatgaagaa taatgtaggt tttgatagta gtttaagtaa
    11341 atttggaatt ggtttgtttg aaactattag agttaaaaat ggaatagcag tagatttaga
    11401 tatccatata gaaagaatgc taagttcaat aaattgtttg gatttagata taaactataa
    11461 aaaagatttc ttgataaatg aaattgttac atatataaaa aaagaaaatg tcattaataa
    11521 agcacttaga attactgttt ttgatgaagg ttataatata tctattaggg atattccata
    11581 taatcaagag acgtatgaga aggggtttaa attagctata tcgccaatag ttagggggaa
    11641 tagtttaatc catagacata agactactaa ttattttgaa aacatatata ccaaaaatat
    11701 cgcaaataag actggttata atgatggtat atttttaaat tcagaaggtg taatattaga
    11761 atgttctatg agcaatattt tctttataaa aggagaaaga gtgtacactc ctagtgatag
    11821 attaccgata ttaaatggaa taataaaaaa aaggattata gagatttgtg acgaattaca
    11881 tatagagttg atagaaaatg aaattaatat atcagaaatt agtagttttg attttgtttt
    11941 tgtcacaaat agtcttatgg gcgctataaa ggttacagaa attgacaaaa taaaatttaa
    12001 taaagaaaat gttgtttttg ataaaatagt gaagttatta gaataaatta aaatattaac
    12061 aatttgttgg agacaaaaga tgataggttg tatttatgaa gtatacaatg aagagatgac
    12121 taaaataata gaaaaccaaa acactttggc tgtatattta gtaggttcta gtaaagacgt
    12181 agattttact ctttatgatg tagagataaa cgatattgat gtgttcgttt ttgtaaaaga
    12241 aggggaaaaa caagagagaa tactgtttaa aaaaaaggga atagaatttg atgtaaatta
    12301 cttttcaaaa gatggtgtaa aaaaattatt atcaaatagg gaatatttct ttgtgaaaga
    12361 aatgaaagat gctaaagtac tgtttgatag ggagaatata tcacatatta taaaagatat
    12421 aagtagagat atttacttag aaggacccag taaaatgtca ttagaggaaa agtcttttat
    12481 aaagcaagat attggagcaa aaatatcgaa tttaaaaaat aaagaaaaat ttgatgtttt
    12541 tgaatatcat tttttgacga atttatattt aaaagatata ataattgggt actttaatat
    12601 aaatgataaa tgggtaccaa aagacaaaaa attgctaaaa gttttaaaaa aagaaaataa
    12661 tgagcttttt gaactagtgt caaaagtaag tgaaaattat gactatcaaa gacttttaga
    12721 tgtttataat tatattttta aagaaattga gacaaaagag gttataaaac taatcttcta
    12781 gtcacaaatc aatgggggga gtttaaatga ataaagttga taaagaaaag atacaacatg
    12841 cagtaagaga aatactagag gcaattggag aagacccaga tagagaaggt ctaatcgaga
    12901 ctccaaatag agttgctagg atgtatgaag agatattctc tggtcttagt gaagaaccaa
    12961 gagaccattt aaaagttctt tttgcagatg aaaaacatga agaattagta ttggtaaaag
    13021 atattccatt ttattcatgt tgtgagcatc atctagttcc tttctttgga aaagctcata
    13081 ttgcttattt accaaaagga ggaagactta cagggctttc taaacttgct agagtaatag
    13141 atacattggc aaaaagacca caattacaag aaagaatcac taaaaatgct gcagatataa
    13201 taatggaaga attacaacct tatggtgtct tagtagtagt agaagctgaa catatgtgta
    13261 tgacaatgag aggtgtaaaa aaaccaggtt caaaaactgt tacatcagca gtgagaggaa
    13321 tatttgaaaa ggacattgcg tctagagccg aggctatgag tttgattact atgaagtagc
    13381 aatttattat agatataatc atttattgag atataaaatt taatttaagg gagtgtcatt
    13441 aattgtgttt gattatggta aaagaactta tataatggga atattaaatg taactccaga
    13501 tagtttttct gatggaggag attttaataa cttggacata gcaatacaac atgcaaaaga
    13561 tatggttgac caaggtgcag atataataga cttaggagga gagtctacac gcccaggtca
    13621 tagctatgta gactcagacg aagagctaag aagagtaatc cctgtaataa aaaaacttaa
    13681 acaggaattg gagataccaa tatcaataga cacttataag gcagatgttg cagaagaagc
    13741 attaaaatta ggtgtcacta tggtaaatga tgtttggggt cttagaaaag ataaaaatat
    13801 ggcttctgta ataggaaaat atgatgcaga agtgtgtata atgcataatc aagatgggac
    13861 aaactatgac aaagatataa tggagtcaat aaaagacttt tttaaggtaa gtatagaaat
    13921 ggcaatgagt tgtggtgtaa aaaaagaaaa aatagtactt gacccaggcg taggatttgg
    13981 caaggatttt gaacaaaata ttgaagtatt gagaagatta aatgaattaa aagatttagg
    14041 gtatcctatt ttgcttggga catccagaaa atcagtaata ggaaaagtac ttccagttga
    14101 gcctaaaaaa agattagaag gtacaatagc tactactgtt cttggtataa gagatggcgt
    14161 agatatagtt agagtacatg atgtttatga aaatttaatg gcagctagaa tgactgatgc
    14221 aatatataga aagtaggtat aatataatgg ataaaatatt acttagtaat ctaggattct
    14281 atggatatca tggtgttctt aaagaagaaa attttctagg tcagaaattc tttgtcgaca
    14341 tggaacttta tattgattca agagaagcag gtcttagtga cgatataaat aaatctgtaa
    14401 gctatgccga ggtttacaat gttgttaaag atattactga aaataaacaa tttaatcttt
    14461 tggaggcttt agcggaaaat attgctgaag aagtcttgaa taaatttata cttataaatg
    14521 gagttatggt cagagttaga aagcctgagg ctcctgtaaa tggtatttat gactattttg
    14581 gtgttgagat aaggagaaca agagatgaat aaggcttatt tgggaatagg tactaacatg
    14641 ggtgatagat ttgataattt atcaagagca tgtgaacttt tgaaaaatag tgattctata
    14701 tataaagtaa aggaatcaag tttatatgaa acaaaaccat ggggatatac agaacaagca
    14761 gattttctaa atatgtgtgt agaaatagaa acagagtttg aaccttatga gttgttagaa
    14821 tattgtcaag aaatagagag agaactacac agagagagaa tagttcattg gggaccaaga
    14881 actatagatg tagacatact attttttaat gatgtagttt ccactgatga aaaactaaca
    14941 atacctcatc caaggattca agacagagct ttcgttttga taccacttat ggatttaaat
    15001 gaagaactta taataaatga aaaaacagta aaagaacatt taaacctcct atctgctgaa
    15061 gaaagagaag aagtaaagga gcttgtaggt tatgaaagaa aacctattta ataataattc
    15121 aaagatagag ataaatacaa ataacaaaaa gataactgta aaaaaggata aacttataat
    15181 agctggacca tgtgcaatag agagttatga gcaacttttg gagactgcta aatttgtaaa
    15241 aagtcaggga gcaaatattt taagaggtgg agcgtacaag ccaagaacat cgccaaattc
    15301 atttcaagga ttaaaaaaag aaggtcttga aatattaaaa gcggttaaag acgaagttgg
    15361 tatggctgtt attacagaac ttatggatgt aagagatatg gacgaactgt atagtataag
    15421 tgatataatt caaattggtt caagaaatat gcaaaacttt actcttttaa gtgaagtggg
    15481 aaaacaaaat aaacctgtta tgttaaaaag aggaatagca tccacaatta ctgaatggat
    15541 aggtgcttct gaatatatag caatagaagg aaatagtaac attataatgt gtgagagagg
    15601 tataagaacg tacaatgatt atactagaaa tacattagat ttagctgcgg tacccattat
    15661 tcaaaaggaa acaggtcttc ctgttgtggt agacccaagt catgccactg gagttaggta
    15721 tttggtaaaa cctatgtcac tggcatcttt tgcatgtgga gcagatggaa taatggtaga
    15781 agtacatcct gacccagaaa atgctttgtc agatggtgct caatctcttt gttttaatga
    15841 atttgaagat ttaatgagat caattaataa ttattaaaag aggcaagagc ctctttttta
    15901 ttcgtaatca ttgctaaggt aaatttataa gttataattt gatagttaga ttatttaata
    15961 taaataaaga tttaatattg atagaattaa tataaaaaat aaaaattttt tgattaataa
    16021 gaaggatatc aataaaaaaa gtcgaattgt gtatattgag tgattgacaa atttagaata
    16081 tagtgtagaa tagaaatgtt aacacaaaaa attacaccag aaggtgataa tatgaatgat
    16141 ataaaagaca ttattgaaga aataaaagct agatgcgata tagcaagtat aatatctgaa
    16201 tatatgaata taaaacaatc tggagctaat tacaaagggt tatgtccatt tcatggtgaa
    16261 aagacacctt ctttttatat aaatacatca aaacagattt ataagtgttt tggttgtggt
    16321 gaaggtggag acgtaataaa ttttgtcatg aaaatggaaa atttggattt tatggatgct
    16381 gtaaaaattt tagcaaataa atgcggtata gaaattaaca ctaacatgaa tgaagaaact
    16441 aggattaaaa tagaaaaatc taagaaattt caagatatcc atacggaagc agctagattt
    16501 tatctttcaa acttattggg aagcaaaaat cttgggtatg aatatttaag aataagagga
    16561 ctagatgata aaattattaa gaaatttggt ttaggatttt ctttggattc atggaattca
    16621 cttatgaata ctctaataag taaaggatac aaaaaacaag acttattgga ttgcggtcta
    16681 attgcaaaaa atagagatgg aactaattgc tatgataaat ttagaaatag agttatgttt
    16741 cctatatttg actatagagg aaacataata ggatttgggg gaagagtatt agatgattct
    16801 ttgccaaaat acttaaattc tccagacaca ttaattttta ataaaaaaca gaacttatac
    16861 ggattaaatt ttgctagaaa aaatttagaa agtaaaacta tagtcttagt tgaaggatat
    16921 atggatttaa tttcgcttta tcagtatggt ataaaaaatg tagtagcaac ccttggaaca
    16981 gccttgactg aacaacaagg cattttaata aagagatatg cggacactgc tattatatct
    17041 tacgattctg atgaagcagg aataaaagcg actttaagag ctatagatat acttactaaa
    17101 ttaggtatca atgtaaaagt gttagactta aaagatgcta aagacccaga tgaatttgta
    17161 agaaaatacg gacttagtga ttataaaaaa gctatggatg tttctactca ctacataaaa
    17221 tataaaatag atcatcttaa aaaagaattt aacattcaaa aagatgaaga acgagtgaag
    17281 ttcgcaaaag aagcttctaa aattataaaa caattgacaa gtcctgttga aattgatttt
    17341 tatacaaagt atttaagcaa tcaaatagat attaatgtcg agtctataaa gagagaagtt
    17401 tatggcaaaa attacaataa gccatataat aacaaaaatc aaaagaaaat agaagaaaaa
    17461 gtaattgaaa aagtcgaagt cagacaagac ggaaaacaat tagttgaaga aactctaata
    17521 aaaataatgt tagaagacaa aaaaattaga gaaatagcgt tacttaaagt agaagaaagt
    17581 gattttttat tgaaagaaag taaagaaatt ttaaattaca tgattaaaaa tcaagaattg
    17641 gacaaaataa ctattgacaa attgaaaagt ttaaacatat ccgaagaata cttaaaagaa
    17701 ttaaattcaa tttctttgaa tagtataaac ttagagaaca caaaagaaat agaaggaata
    17761 ataacaaata tcagaaaaaa ctcattagaa gagcaaatta atagcttgtt gagagaacaa
    17821 caagaattag aaaataataa tgatatgaaa gaggtagatg gtagagttat ggaaattgct
    17881 ttaaaaatag ttgagataaa taaaatttta aagagcttgt agagaaagga ggtttgagtg
    17941 tggaaaataa atcgaataaa aaagagttaa aaaaggttac tgctaagaca ttaatagaaa
    18001 aaggaaaaaa gcaaggttct ctgacacttg cagagataat ggaagctttt tcggagactg
    18061 aacttgataa ggatcaagta gaaaatcttt atgagacttt aggaaatttg ggaatagaaa
    18121 taacagaaac aaaaaattat aaagctgata tagatttttc ggttgctgat gacgatttaa
    18181 gtataggcca cttagatgaa gatgcagagg caatttcaca tgatgactct tctgcaatag
    18241 aaatagaaac tgtggattta tctttaccaa aagggataag tatagatgac cctgtaagaa
    18301 tgtacttaaa agaaatagga aaaattcctc tacttaaacc acatgaagaa gtagaatttg
    18361 ctagaaggat gcacgaaggt gatgagatag caaaacaaag gttagttgaa gcaaacttaa
    18421 gactagttgt aagtatagca aaaagatatg taggaagagg tatgcttttc ttggatttaa
    18481 tacaagaggg aaatttaggt cttataaaag cagtcgaaaa atttgactat acaaaaggat
    18541 ataagtttag tacttatgca acatggtgga taagacaagc tataacacgt gctattgcag
    18601 accaagctag aactataaga ataccagttc atatggtaga gactataaat aagctaataa
    18661 gagtatcaag acaactactt caagaacttg gaagagatcc aaaaccagaa gaaattgcaa
    18721 aagaaatgga aatgacagaa gataaagtaa gagaaataat gaaaatagct caagaccctg
    18781 tgtctttaga aacaccaata ggagaagaag aagatagcca tttaggtgac tttattccag
    18841 atgatgatgc tccagcccca gcagaggcag cagcatattc tttattaaaa gaacaaatag
    18901 aagatgtact tggttcatta aatgatagag aacaaaaagt attaaaactt agatttggtc
    18961 ttgaggatgg tagagccaga actcttgagg aagttggaaa agagtttgat gtaactagag
    19021 agagaataag acagatagaa gcaaaagcac taagaaaact aagacatcca agtagatcaa
    19081 aaaaacttag agattattta gactaaaaag acacatcatt aatgtttttg tgataaatgc
    19141 catgagataa gtgatatctc atggctattt tgtagtaaag atttaatttt atttttgcag
    19201 ttatttcagt ctaatatcta taacttgtat taaatcctat aaataaaggg aattgaaagg
    19261 agaattatat ttgaaattaa cagatagatt attgaaaata gcatcattag tgtcagatgg
    19321 taaaaaaata gctgatatag ggacggacca cggatacata ccagtatatt tgttaaaaga
    19381 gggaaaagta ccatttgcag tgctagcgga tgttaataaa ggacctcttg acaatgcaca
    19441 taaagaagtc atacagaaca atcttttaga taaagttgat ttacgattgg gttctggtat
    19501 agagatactt gaaatagggg aagtagaaga agtgataatt gctggtatgg gtggaatctt
    19561 gataagtgag cttctcgagg ctaaaaaaga agtagcacat aatgtagaaa aattaatatt
    19621 acagccaatg caagcacaag aagaacttag atattacctt ttaaacaacg gatatgaaat
    19681 tttaaaagaa gttttagtga gagaagattt tagaatatat gagataattg ttgccaaata
    19741 tacaggtaaa aatactataa tagaagatga gatatattat gaggttggaa taaagctttt
    19801 agaaaacaaa gattctcttt ttaatgattt tatagaaaaa aagataaaga catatagttc
    19861 tatagttaat aaattagaag ggaaaaatgg ggaagctata gataagaaga gaaaggaaag
    19921 cgaagttgca ataaaaaaac ttgaaaattt aataaaataa ataggaggta tatatgctat
    19981 taaagagtct aactggaaaa attgaaaaaa agtatcctct aaacttagca gaggattggg
    20041 ataatgtagg tcttatagtt ggagattttg atatggatgt aaaaaaggta ttggtatctt
    20101 tagaagctaa tgaagatgtt attgatgaag ctatatccaa aaatatagat ttaattgtga
    20161 cacatcatcc ttttatattt gggaaaatta ataaaattaa tagtggagat ttaaaaggca
    20221 gacttatcca aaaacttatt aaaaatgata tatcacttta ttctatgcat acgaattttg
    20281 atatagcatt tgatggtcta aatgactatt ttatggaaat tatggaattt ggtaattcaa
    20341 aggttttaga tataactaaa agcgaaaatt tgtataaatt agcagtatac gttccacata
    20401 actattcaga tgaacttaga aaggttttaa gtaattcagg agcaggtcat atagggaatt
    20461 atagtgattg tacgttttca atagaaggtg aaggacaatt taagccatta gaaggctcta
    20521 atccgtttct tggaagtgta aatgatatag aaactgtaaa tgaagttaaa attgaaactg
    20581 tagtaccaca gaagctttta ggtggggtaa taaattctat gttagatgca catccttatg
    20641 aagaagttgc atatgatttg tacaagttag aaaataaagg tgagatattt ggactaggta
    20701 gaataagtaa acttgataaa agtatgacat tagaaagtct ttcaaggaaa ataaaagaga
    20761 aattaaatat gaaacacata agagtagttg gaaaccttag tacagacata acgaaagtag
    20821 ccgttgtaac aggagctggt tcagaatttg taaaaaaagc taagagacaa ggtgcagaag
    20881 tactaattac gggtgatgta aagtatcatg aggcacaaga tgcacttgat attggaatgt
    20941 gtatagtgga ttgtggtcat tttgatacag aagatatatt caaaaatgtt atgaagagat
    21001 ttttagatga atttagtgaa attgaagtaa taaagagtaa tgtatatttg aatccattta
    21061 gtactattta gaagtgtttg attaaaaaat actatataaa aaataaattt gagtttaatt
    21121 agggggataa tgatgaaagt agcagtaatt tttcatagtg tttgtgggag tacatattta
    21181 ttagctagag aatataaaga agtgcttgaa gaaatgaata tcgaggtaga tatatttaga
    21241 gtaagtgacg aagttgcaaa aacacttcct caatattatt tgataaattc caaagaatac
    21301 aaagacgaat ttgaaagtat aaatgtaatt aaatctggaa aagaaatatt agattatgat
    21361 gctatattta tgggttcacc aacatattat ggaaatgtat ctggaccaat gaagatgttt
    21421 atggatagtt tttctgatat ttgggtaggt gctcctttga gtggtaaaat atttggttgt
    21481 tttgctacag caggttcaca acatggagga ggagaattag ctttgcaagc tatgaatata
    21541 tttgctcaac atatgggaat gactcttttg tcagttccat gttcagtaag aggaggttat
    21601 ccagcgtatg gaatacttca tatagcagga gataattctg atataagacc aaatgatgat
    21661 gccaagatag gtataagaga ttacctaaaa agacttaaca tataagaata tcatataaaa
    21721 atacctaaaa gtagctgtat atacttttag gtatttttac ttaattataa acgtgaagct
    21781 ttaccagaaa tatggtcaat ttctatttta acaacagttg ttaagttcat atccttctct
    21841 atgtacttca tgccttcttc aaagaatcct ttagaatatt tttttattat ttctacaaga
    21901 gcatttttct tttcttcatt ttctacagtg caagcttttc caaaaactat agcactagaa
    21961 taagtagtac taaatttatc tggaataaca ctttcattag caactactaa aaaagaaact
    22021 ttgttgtttt tcgatatatt atctaactta tgtccatttc ttgcacaatg aaagtaaata
    22081 gaatcattaa agtatacata atttacagca accccataag gataaccatt ttcagatata
    22141 gtggaaaaag taccaaattc accatttttt aatacttcaa cagtatcttc ttttgtcatt
    22201 tctctttttt tcaatctcat ttctttaaac ataatatcat cctttctaat tttgatgctt
    22261 aaattaaatt ttagaacatt tataaagatt atgctatgtt ttttacaaat tttaagaaaa
    22321 aaatatagtt taagataaaa ggtagtgaaa gagaagctat ttggaggttt atttatgata
    22381 ttattgttag agtagtacaa acaatactaa taaatttaat agctggtttc ttgttattta
    22441 aggtagtaag catgtctata agaaggggaa gttatcgagg gtagaagttg ttatttataa
    22501 cgatattata aagaaaatat tattatataa aataataaat agtaaagagg tatcaagttg
    22561 aatataatac ttaatacctc ttcaaaatta agttataaaa gtgctgtggg aattgtccta
    22621 tacatggtaa ggagataata aagaatgtat ctttaaagtc tcagctaaac agcaaaattt
    22681 atccaacaaa catacaataa atgcttcttt gtatctaggt ggcttaacag taagtggcca
    22741 catgtgtttt aaaattatgt ccgtttcttt ttcatttatt tgaaaaaata aagttgcatt
    22801 ttttaatgct tctctagggt gagtaaatcc atgtaatcct tttctatcac ctttgtaatg
    22861 ccaatcataa agaaaaaagt cgtgtagtaa agctcctcta ataacacttt gaatatcaac
    22921 acttaagtgc aattttttac ataatagata actataatat gctactgaca aactatgttc
    22981 aagacatgaa acattgccat gatgaggaaa tgttctcata agttgaactt tttcagaaga
    23041 aagtatctca gaagcacatt cattaaaata tttgatttca gcttttgaca acattatgaa
    23101 aatctccatt cttagtaata tataaatact atacttcaac gataatatga aatatttctt
    23161 atcctacaaa atataatacc caataataca agtaagatac cttttatggt attttaaagt
    23221 aagagagatt ttattaggct aaacaatgaa aaaattaaaa gtaaagctat agcaatatat
    23281 agtatttttc caagaggatt gccaaaattt atagtccatc caataccaaa ccttttatta
    23341 accattaatg atgggtcatt tggattatta tacatgatgc ctgctatcca atacttctca
    23401 tcttcttctg gagaataaga tgagttgaat tttaaatttg gggaattaat atatgttgct
    23461 attaaataaa ttataactaa aagcgttgta atattcatag cagttgatag ttttgttttt
    23521 attgataaaa gagtagtaaa aaactgtgtt gtcattataa tcatcaatat taaaaacaaa
    23581 taaccaattt tatttaaata tttaatgttt tcaactctac tttcttcaat tctatttgta
    23641 tctatcttaa tccttgactt tatggatcca atggaagtta tatataataa aaccattaaa
    23701 caaaagtcag taccgattaa tttaaataca ttaagaaatg atttatctat aaaaacatca
    23761 ggagacccat ttatgttcca atgagtggca attgagtctg gcaattgatt ataattaaat
    23821 gctataaaaa tactcattcc caaagtaaat agtatcggta ttaaatagat tattttaaat
    23881 ttttttatta ttttattttt cttatttata aaatccatat ctactattaa ttttgaatct
    23941 acatctatat gacctaattt agaataaatt tctgatttaa gcttcttagc ttttttatgt
    24001 gtatgaatat atagtatact ctcatataat aaaaaaccta taataccaat aaaatatgaa
    24061 agttccaatt tattaaatgt aaaaaccaga ataaaaacta atataaagtc tataataaaa
    24121 cctaaagata atagtttttt aaattcttta tctaacttta taaagtaatt ataattttta
    24181 tgctcttggt ctatagaaac tccatagatg tgttttttac ctacaaaata gggcataaaa
    24241 taaaatgtag catacatcaa aattagaact ggaaatattg taaatagaca ttcaatctta
    24301 ctcataatat ttcacctcat acttgtcaaa taaacttgaa cttagtgaca aaaattcttc
    24361 tttactaata cctgataaat aagattttgc caccaataat tccaagtcaa gtttattttt
    24421 ttgacgagtt gtattatcta ttttcattgg tagttgagct acaatagcac cttttcttct
    24481 atcaatattt aagaatccct cttcttttaa ttcattgtag gatttattca ctgtatgtaa
    24541 atttacacca atattttcag ccatacttct tacagatgga agtgattcat ttatttttaa
    24601 ttctcctgaa gctatagctt tagttatttc ttctttaatt tgtacataaa tagatttatc
    24661 actattaaaa tctaaattta aaaccataaa aaacctccat tatgctttat aaatgaaaac
    24721 gattgttata tacatagtat aacataaaaa ataataacaa acacaaaata taaatttata
    24781 ttttgtaaaa attgtaattt aaaaaataac ataattttta ttaaaataat acagatacta
    24841 tttatagata gaaataaaaa ttagaaagga gaaaaaatat gttaacatat ttaatgaaaa
    24901 gacaaatgca taaaaaagat gatggaatga gtaaaccaat gatgattaca ggagctgtac
    24961 ttacaggtgt aggagcatat gctgtatata aaatggtaaa aagccataaa tctaattctc
    25021 aaatggttga tacaaattat tatggaaata gcgattatga tgattataaa tatgacgaat
    25081 ttgattatga ctgtgattgt agagacacaa aacaagatta tgaatatgaa gaattaaaaa
    25141 aaaaagtaaa agaatttaat tcaagaagaa taaattgtga aaattgtcca catgtttctc
    25201 aagaagaaat gatgcaatat gtaaatagtg ttaaagatgt aaaggaagag attgatttac
    25261 atgaagatgc taaaaaagat aatatttaca aagaagatga atacaaaaaa tatgaagaag
    25321 aataagtaat attctgtata actgaacaaa tagtaatgtc aaattattta atatctagtt
    25381 ttaatatgta agttgtaact taacttgaaa gaatcagtat cattctttag atagttaagt
    25441 aacaacttac attttatttt tataaatttt aatagctctt tgtgactatt ttgtaatttt
    25501 agaaatattt tagtatccag agtaattgtg tataataaaa cttgtataga tagatagtat
    25561 gaaattaagc agatagttta aaattaaaat gaaaagaaag gaaaggaaat agttatgtta
    25621 aagttgttgc tagttgaaga tgatagtact atatcttttg gaataaagta tgctttagaa
    25681 caagaaggat ttagtataga tatatcaaag gatttatcta gtggaaaaga aatgatttct
    25741 tctaatgaat atagcatgat actgttggat gttacattgc cagatggaac tggttatgag
    25801 ctttgtcaat atataagagg attctctcag gttcctataa tattcttgac tgcttgtgat
    25861 gaagaagtaa atattgtaat gggtctcgat ataggtggag atgattatat aacaaaacct
    25921 tttaggatta gagaattaat atccagaata aaagctgttt taagaagaaa agggaatacc
    25981 ttagaagaaa gtaagaaaat acttaaattt ggagatttaa gtatatatac attagaagct
    26041 agagtatata aaaatgataa agaaatattt ctgacatcag ttgaatataa acttctttta
    26101 attcttatac agaataaaaa tactgtttta agtagaactc aaatattgga aaaactttgg
    26161 gatgtaactt atgattttgt aaacgacaat actctaactg tttatataaa aaggcttaga
    26221 gaaaaaatag gtgatgattt atgtgaacca atctacatag aaactgtaag ggggattggt
    26281 tataaatgga taggaagtga aaatagtgtt tctatataat ccagaagtga agaagttttt
    26341 aagtaagtat gttactttga tgtttattgt tatcataata tctattggat ttagcataat
    26401 caacgtgtct ttaactaaag agatggttgt aagaaataat caagctataa tagggacttt
    26461 atcgagtaag tatccaaact tagaaagtca gatagtagac ataataactc aagggaagtc
    26521 tatgaagaac atagattatg gtcagaaaat attaagtaag tataattatg ataaatctat
    26581 taagataaac tctgagccta ttatttctaa attagtttta gagactatca aaataaatat
    26641 aatattagta tgtataatat ttattttgat atttgtgttg gttgttagat attttacgtc
    26701 aatttacaat gatttatcag atatgactaa gtatgtttac tatagttcag agggtaagcc
    26761 atttgatatg aaaaacaaga atcaagaagg gcagataggt cttctaaaaa ctgaactctt
    26821 aaagatgacg acaattctta atgaaaaggt tgaactttta aaaagagaaa agatattttt
    26881 aaacaataca atttccgata tatcacatca attaaaaact cctatgactt ctttaataat
    26941 gttgaatgat ttattatata atgatgtacc atacgaagta aaaatcgatt ttttaaataa
    27001 aataaaaaat caattaaata gaatggattg gttgattaaa agcatgctta aattatcaaa
    27061 ggtagaagca aaagtgataa attttaaaaa agataaggta aaatttagtg aactcataca
    27121 tagagcaatg ctatctatga aaatacctat ggagattaaa aatcaaaaac tgactataga
    27181 gggaaatgat aatgtatctt atattggtga tattgattgg tctgtggaag cactagtgaa
    27241 tataatcaaa aattgtgtag aacatactcc tgaatttgga aatataatta taacctataa
    27301 agaaaatcca ttattttctg aactaataat aaaagatgag ggtgaaggta tagataaaaa
    27361 agatatacca catgtattta aacgattcta tagaggaaga agtagttcaa aagaagatag
    27421 tgtaggaata ggtcttgcaa tgtcaaaatc tataatagaa agccaaaatg gcgatatata
    27481 tgtaaacagc gaaaaaggta agggtacaga atttcatata atatttcata aaatgtatga
    27541 tagtgactaa tctgtaatat ttaattcact ttatagtaat agccaaaacc taatatatga
    27601 agtatagaat ataaatattg gaggtagtta tggaaatttt aagagtagaa aatctaacta
    27661 aaagttatgg taaaaatgaa acaaaagttg atgctataaa aaatgtaagt ttatcagttg
    27721 aaaaaggaac gtttatagca ataacaggtc caagtggaag tggtaaaagt accttattac
    27781 atttattagg aggagttgac agaccaacta gtggtaaggt ttatataaat gatgttgata
    27841 tatataattt aaaaactaag gatttggcga tatttagaag aagaaatata ggtcttatat
    27901 atcaatttta caacttaata ccagtcttaa atgtgaagga aaacatattg cttccagcag
    27961 agcttgacaa tagagatatt gatagagaat attttgatga tttaatgaaa acattaggtt
    28021 taattgatag agaaaagcac cttccaaacc aattatcagg aggtcaacaa cagagaacct
    28081 ctataggacg tgcattaatt aatagacctt ctataatatt agcagatgag ccaacaggta
    28141 atttagatag taaaaattca aaggaaatat tagaattgtt aaaattgtca gtaaaaaaat
    28201 acaaccagac actaataatg ataactcatg acaaaaatat ggcacttcaa gctgatagaa
    28261 ttataagcat agaagatgga atcataaaaa gtgatgaggt gatgtagatg aatttatata
    28321 catcactaac tattagatac ttaaaacaaa ataaaagaag aaccattgta accataatcg
    28381 gtataatact ttcaacagct ttaatttgtg gtataggaaa tatatttgaa agttttatgg
    28441 attatcaaat gagagaaact ataaagaatg atggaagttt ccatgttaca ttttatgatg
    28501 taaatagaaa aaatgtggaa tatgtaacga aatcagctga aatagaaaaa catgcattta
    28561 ccaaacaact tggatattct aaattagaaa atagtgaaaa tgctatatta agtataaagc
    28621 aatatgataa aaatgcaata aacggatata aagtttctat aaaagaaggt agatttccag
    28681 ctaaggaagg agaaattgtt ctaagtgaaa gtattattaa tcttatagat gataagttaa
    28741 aaataggaga taagataact ttaaaagtag gggatatgtt tgattcaagc aagaaaaaga
    28801 ttgatagtat gacatttcat gaaggtgatt atatagcaaa tgaaaaagat agaactttta
    28861 aagttgttgg tataattaaa aaacctgggt ttgaacgtta taatggaatt gcaactgcta
    28921 tagcctactt taatcctatg aataattaca atgatacaat taatgtatca gtagcagtaa
    28981 gaaatcctaa agatgtgtat aagataagta ataaaataag taaaaatata tattcaaata
    29041 aagataaaga agcagtttct gatatgataa aatacaatga acatttattg aggttacaag
    29101 gtgctagtaa gtattcaaat ataaatagct ctataaagtc tataattata gcagtaacta
    29161 ttttagtaat catatgtaca attgctacag tgtacaattc ctttagtatt tctataaatg
    29221 aacgaaaaaa acagtttggg atattaaatt ctataggtgc tacatctagt caaattaaaa
    29281 gatttgtttt tatagaaggt attataatta gtttaattgg tataccaata ggactaatat
    29341 ctggaacagt agcgatagac ttattgttta aaattataaa taagtatttt actgaatcgg
    29401 ttgttactaa gatgagtttg cagatagtgt ataatccaat aataattatt gttagtataa
    29461 taatagtttt gcttacaatc tttatatcaa ttctactacc tgcaatatcg gcttctaata
    29521 tttctcccct taatgtgatt aaaaatactg gagagtataa agtgggcaaa atcaaaagct
    29581 caagacttat taaaatgatt tttaaaactg aaggaatact tgcatataaa aatattagga
    29641 gaaatagaaa aaaatttata gtaactcttt tttctttaat ggtaagtata ataatattta
    29701 tatcttttag tggctttaca ttacttttac taagaagtga agaaattaga aattctcaaa
    29761 gaaaatatga tttgtattta actgcaaaga acacagctag gtctgtagag gatactataa
    29821 gtgaactaga aggtattgat gggataaaaa actttgaatt ggcaacagga caatatgtgt
    29881 ctataagagt aagtgaaaat aaaataaata aatccaagga agatttaatc aggaaatatt
    29941 atcaaaaata taagattgga gatagttatg aatatgattt cagtaataat gaattaattt
    30001 ttccaggaga ttttgcagta aaaaacaaaa taaataactt agtacagggc tcttttaata
    30061 aagagagagc aattgaagaa aatggtgtta tattagttag aaaaagtgca tttgaagaaa
    30121 atgggaagaa aggtgtagta gaacttacca actataaagt aggagataca gtaaattgtg
    30181 aatatcttga tgaaaatgcc ttaagtaaaa aagtaaaggt caagattctt gctataactg
    30241 atgaagaacg tctaggtttt ggttatcaaa atatggggtt acaatttata acttatgatg
    30301 aagttgctaa aaatttaaat ttaaaattaa gtaaaagcct tatatttatt gattcaggag
    30361 gaagcgttaa gactaagaag gaaatagaag ctttggcaaa taaaaataat tttaactttt
    30421 atgatgaaat ttcaagcagt gaaagtgaaa aacaagattt aaaggttatt aaaatatttg
    30481 tatatggttt tatagtagtg atatctttag tgagtgttac aaatattcta aatacagtaa
    30541 gtacaagtat aaatctaaga aaaagagaac ttgcagtaat acaatctata ggggttactc
    30601 ctaaaggatt taggaaaatg atatatttag aaagttttat atatggtata ctgtcattgt
    30661 tgtttggaat accaattagt attggtataa ttctaattat gaataaactt atttcaggtg
    30721 taattgaatt ttctccgatt ataccgtgga cagccatagt tatctgtata gtaagtgttt
    30781 ttataataac ttttatagca gggtatatac caatgagtaa attaaataaa gaaaatataa
    30841 tagataatat aagaagagaa agtatataga tataaaaata attcttaact atataaaata
    30901 ttattaaaat catttaagtg gtataaaata ttattatatc acttaaatga ttttttattt
    30961 atataagaaa tctaataata aattactaga ggtatttaac tatttagaaa gaattggtat
    31021 tatataaagt aagagaatat ataataagaa agaatatttg attttatttg aaaacaaaag
    31081 aaaaagaagg tgattactat ttctcatata actgcgaaga atatgtataa aagtttagag
    31141 gaaagaataa acaagtttcc acaaggtgct ccaccatctg atacattata caaaatacta
    31201 aatgtactat atacagaaca agaggcgaag ttagttgctc agcttccaat aaagcctttc
    31261 agagtaaaaa cagcagctaa aatttggagt gtaagtgaaa gtgaagcata tagagtattg
    31321 gataaacttg ctagtaaggc tctgatacta gatatagaag ataataaagg gaagaaatat
    31381 ataatgcctc ctccaatggc tggttttttt gagtttgcca tgatgagaac gagacacgat
    31441 atagaccaaa aacttttggc agaactttac tatcaatata tgaatgtaga agaagatttt
    31501 atcaaagatt tattttattc aacagaaacg aagcttggaa gagtatacgt tcaagaggaa
    31561 gttttaacta atgataatga ggttagtatt ttagattatg aaagagctac tcatataatt
    31621 gacgaatcaa ctcatatagg tataagtatg tgttactgta gacatagaat gcaacatgtt
    31681 ggaaaagctt gcgatgctcc catggatata tgtatgacgt ttgacaatgt agcaaattct
    31741 ttaataaata ataaatttgc aagacgtgtg gataaaatag aatgtaaaga actgcttcac
    31801 caagcatatg agcataactt agttcaatgt ggagaaaatg ttaggaaagg ggttacgttt
    31861 atatgtaatt gctgtggatg ttgttgtgaa gcaatggtag cagctaaaag atttggaaat
    31921 cttcatccag tacagacaac aagttttata ccaaatataa accatgaaaa ttgtgtaaag
    31981 tgtggtaaat gtataactgc atgtccaata gatgcgataa gcaaggttaa ggaaggtgat
    32041 aaagaatata taaaaattga tgaggataga tgtctaggtt gtggagtttg tgttagaaat
    32101 tgccataaaa atagcattat gttattaaag agagatgaaa aaataataac tccagcaaat
    32161 tcagtacata gagcagttct catggcaatt gaaaaagggc agttacaaaa tttaattttt
    32221 gataataatg ctctggctag tcatagagct atgggagcta tactgtcagc tatattaaag
    32281 cttgaaccag ctaaaaagat tttagccagt aaacaattaa agtcagtata tttagataaa
    32341 ttgttaagta tgaatgataa atagaaacta acttaaaaaa ggcaaagttt tagacttatc
    32401 tatatcttaa taaacttatc atttaatatt taaatttaat ttttacacat ataaaactta
    32461 taacttaaat aaaaaaaggc tatattcaat taatattact tgaatacagc cttttttagt
    32521 tatgttaagc tatttctttt atttgcttaa atgagttttc atttccattt ccaccaattt
    32581 gtgttacaga tttaaatctc atagttttaa atagttcttt ttgattataa tctagtgagt
    32641 ttcctactag cattacagga gatttagttt ttccagccaa aactccaaca gataatccgt
    32701 ctattaaatc atcttgttta ttcattccat ttttagcaac atataaattg tctatcttag
    32761 aatccttgta aaattctttt attacttttg cattagtttc atttctagtg ctacctgata
    32821 ttctctgtgg attttgaagt ttattttcta tatttttaga aactgtatat tctccaccga
    32881 ttacataaga tttatcaatc tttttgtttt taaacaagtt atttatttca gttatattac
    32941 tattttcatt agtaagtatt ataggcatat cattttgagc tgatacagct ccaatgctta
    33001 ctgcatcggc taatcctttt tcgccattaa ctactgaaat ctttgatata ttgctaatat
    33061 tgttcaattc tttagcaatg ttcatagaag tttgatatct atcacttcct gaaattctag
    33121 atacagagat attgtttgat tttatagtat ctaaagattt ttcatttata gaagcctctc
    33181 caccaactac atatacattt ttaactttta atctctttaa ttcagccaaa gttttttcat
    33241 ttatttgaga gcttccagtc aataatatag gagcgttttt cttgtatgca aatggtgttg
    33301 cggccaaagc atctgcaatt gctgaatcgt ttattaaaac tgcattttca gcattttccc
    33361 aacctgcttg acttatctta atagaagttt catatctatc agttcctgta agtgcacttg
    33421 catttacttc atcttgatat gtaacctcaa atctagcatt tggacttcct aagaaaacaa
    33481 ttacgcctcc ttttggcaat ctaactctat tgttctttgt aactaaagaa tagtttacag
    33541 gaacaccttt atcatcataa acagcaaaag ctgaattttg aggaagatta acttctattt
    33601 ttttatttgc gatatcgtca ccaatcttat accattttgc ataaccattg gattctagtt
    33661 cacaagtaaa agatttttct gctggcaaat tagttataga atcttcacta acatacgtta
    33721 gtgttccaaa agataaatac tctgtaccat tttctttatg aagtttaatg tcggataaat
    33781 cacgacctat tacaccaggt atttctataa aagcatttga gttattctca tccattattt
    33841 tagtgttaac tatataacct ggagtttcat cagaaagact aaaacttgct tttacagagc
    33901 caaacatata gctttgagaa gtatattttt catccactag atagtaacct ttgccacttc
    33961 tttttttcca cacttctttg acactatttg atatattatt gtcatctact ttttgagcta
    34021 catagtataa acttgctgtc tgacctaatc cagggacatc atcataagag ctcatattta
    34081 aatatgtgat attatttttt tcttttacaa attttaaaca actgttaccc ttttcagata
    34141 caaatctatc ttgacctatg tatacgtatt tatcttcagg tccattttct atataaggag
    34201 aagatactgt taaagtacca ttatcattaa catctacttt tatcatattt gaagaagcat
    34261 aaagaccact attttctttt agagagctag gcattttaac ttgttgtggc ttactaaatg
    34321 ttttatcagg ttttatttct ttaattttac ctttttcttt taatgcagat agtaagattt
    34381 cttgtccaat tatttcgtta agttgactac ttccaccaga agaaagaact gcaactgcca
    34441 tattttcatc tggaagaact ataagattac tgtggaataa taaagagtct ccaccttttg
    34501 taagagcttt taaattatac tgattaaatg gataagtgtt gacacaatcc caccctaaac
    34561 catatccaag tatagaatct tctccttcag gccatagacc atttaaatat tctttgtttt
    34621 ccatagcttt tactgaagca ggagaaagaa taccatttga atttttcata aatgtttgtg
    34681 caaatgtaca tagattttct gcacttgaat ataaaccacc tgcacctata gcattaaggt
    34741 tatcttgtgg aactgcatct tcccaataag gtacatatgc ttttgctagt tttgaactat
    34801 caaaactatt ttctgtagtt tttgtatttt gtaagttaag tggattattt atgtatttat
    34861 caagaaaatt agtaaatgac ataccagata ctctttctac taaaatttca gctaaagtaa
    34921 atccatcatt acaataaaca gaaaaagctc ctggtttagc ttttaatctt tgtttttgta
    34981 attcttttaa gaaattatca tgaccataag aatcattgtc tgctaataaa atagtgtttt
    35041 taaaactact tcccatcaac cctgatgaat gatttaataa cattcttgga gtgatttcct
    35101 tgtatctatc atcagccatt ttaaattcag gtatatactt tacaacagga gtatctaaat
    35161 ttaattttcc atcatcaacc aacttcataa cagctgttgt agtaaacatt ttactgatag
    35221 atgcgatact atacatatta tccttattta agtttttgtt atcctgtttg ctgtaaactc
    35281 caccattacc agaaatctca attttgccat tatcaatcaa agcatattga gcacttacag
    35341 caccatactt tgatagcaaa gtttggattt tctctttagc aagagcttta gtttttgtgt
    35401 aagattccgc gtttttacta taatcatgta attctatatc agaactttga tatttttcgg
    35461 aattatcttt tgtattatca gcaaaagtaa tatttggagc agcagtaaat aacatactca
    35521 atactaatgt actagataat aatttagaga tcctttgctt aaacatatta cattacctct
    35581 ttcccttttt aataatttat aattagcata acattcttaa ttattttaat caacagatta
    35641 ttatcaataa aaaaagcttt tataagtata gctttttata taacagagaa aaatataaaa
    35701 ataatatttg ttgttgtata aagaataaag ggtataggta atatataaat aaaatggagg
    35761 aattttagac atatgtataa gaatataaat aagaagcaac ttaaagaaat gatgaaaaat
    35821 gaaaaggatg ttttattatt agatgtaaga actaaagatg aatttaagga atataaaata
    35881 gaaaatgcta taaatatatc tttacaagat ttaatcaata atatagatga aatttacgat
    35941 tataaagata agaaagtagt agtttattgc agaagtggtc atagaagtgt tactgcatgt
    36001 aatttgttag ctgaagaagg ttttgagcat ttatataatt taaattcagg aataattgat
    36061 tatatgagtt aaataaggta agttatacat taaatactat gtatagctct gtttattaag
    36121 taggaatata tctaaatatt tataagataa atttaggaaa gaacgaattt tttcgctttt
    36181 ttctatgaca gtttttgtag taaatattag tttttaagtt ggaaaaaggt agtagctttt
    36241 tagctactac cttttaatat gaacttagaa tattattaaa aaaatatatt taaagacaga
    36301 attaattttt taatgaccag ttaaattact atcgccaaat ttatcattaa atggttttat
    36361 aactctattt ataggtcctt ttagaagtac gtttaaacaa atagacagaa tcataaatag
    36421 taatagaact agtatatctt tagttagatt tggagcatat ataccaccaa ctgcttccct
    36481 tgtagcacct attgcatagg taaatggcat tatagggttt attctttgga agaatgtagg
    36541 tgtaacttgt atagggaatg taccaccaga agaaccaatc tgaacgacta atagtactat
    36601 tgcaattgct tttcctacat ttccaaatac agaaactaaa gaatacacta taaagttaaa
    36661 taccatacta gtaaacataa gcagaactat caataaaatt ggatgttttg ctgttactcc
    36721 taacaataat atatctccag ttcctattat aaaaccttgg acaagagcta tacttaaaaa
    36781 agtaagacct cttccaaagt aaatttcata aggtttatag tttccatgta cagatgtaga
    36841 caatagtgct gaaataagta atataccaac ccatgtagaa agaacactat aaaatggtgt
    36901 cattgcagaa ccataatttt caattggata taatttctct gttttcacct caacaggttc
    36961 ttttaagaaa ttagactttg tcaatatatc actttcaagc aagctgacta attttttcat
    37021 atcttcacca ttactaattt tgcttaaagt atcaatcaaa tcatccaaca taccttttgc
    37081 taaaggaagt ctttctctta tcaatgatat actttcctgt gcatttcctg aaagttttag
    37141 agaagtagta agtatttctt caacctttgg aagttttgct tctgccttat ctaaaacagt
    37201 aattatatca tttgctactt ttatactgtt tgcaaatata ctatttatag gttttgatat
    37261 ttttgagtca aaattattta aaatatttaa attaattctt ccaataccat ttgatagact
    37321 taaaacatta ttcaaagcgc ttatagatgg ttgttgtcca gatataactt tgtttttaat
    37381 atcatttaat gttgatatag atgaatctat tttattgcta gagtcttcaa gattatctat
    37441 tacatcatcc aatctattat ttgatgtaag ttggtttaat ttagttaaaa agtccaccaa
    37501 agtatcgttt aaagattgca aattagaaag tttttctgat aaattatcta tcaacttagg
    37561 tacatcttca ctgccactat ttactgcatc aattaaattt aatgtaagag aagaagcaga
    37621 agatgaaagg tcaaccatta aatttaagtc agacttaata agaggagaaa gttcgtctaa
    37681 attatcattt gtatcctcta agaatttttt taagtcactt gataatagtt ttgtatcatt
    37741 cagagtcttt ttaattgtag gtaaatcaga tttaatatct ttaactgtat cagataattt
    37801 tgaagtagca tcagaagcta aatcaacagt cttatttata tggtcaaatc tcttttgaag
    37861 gtcaataagg gaattttcaa cttttgtcaa ttttggaaga ctgtgttcaa ttcctgcacc
    37921 aactccgttt gatataccaa gaacgatttc actaactgtt tttactatag tctgattaac
    37981 ctgtagttgt attgtagaag cacctttatc tgtaatcttt ggtgcaactg catttatttt
    38041 ttcattaaca gtatagataa tttcgccttt tttaacatca tctgtaatta aagatgtcaa
    38101 atcttttgta aaattttttg gaatcttaag tgatgcataa taagtacctt ttttaacacc
    38161 ttcaagagca gttttttcat ctacaaactg ccaacctaaa ctcttgttat ctttgagttg
    38221 ttcaattaat tggtctccta cattaatctt ttgtcctgct atttcatttc ctttatcttc
    38281 atttgttact gctacaagca tattagcagt gcttccataa gggtcccaag atgcctttat
    38341 attgaaccaa gcatacagag atggtaaaaa agcaagacct aaaactatta caagtacggc
    38401 ataattgcca cgtatatctt ttaggtcact tttaaaaatt tctaatatat tttttaaacc
    38461 ctttgaaggt cttaaattct tgatattatt ccagtttaaa atttctttta aactattagt
    38521 ttttttcaaa tgtctcacct cctaaaatat tttgataaag aaaaaagtta gatttataat
    38581 caattttaaa ttatattact ttttacacaa atagtaaagt taaaattttg tcttaat
//
LOCUS       DACTZW010000035        38630 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.035, whole genome shotgun sequence.
ACCESSION   DACTZW010000035 DACTZW010000000
VERSION     DACTZW010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38630
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.035"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(<1..567)
                     /locus_tag="JAM15_09355"
     CDS             complement(<1..567)
                     /locus_tag="JAM15_09355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6798456.1"
                     /translation="MRLKNLILGDIKFQFKYGFYFLYLFLSIIYICIINVFPTFMREK
                     IAIIMIYSDPAAMGLFFMGAIVLLEKSQRVLNSLAVSPVKVSEYILSKVISLGVISSI
                     VAMFIAITLNLDNIIISTIGTFFSSIIFSLLGLILASKASSLNQFIVLSIPIEIICFI
                     PPILNVLLDTKSYANLYPFNICISLISGD"
     gene            complement(564..1409)
                     /locus_tag="JAM15_09360"
     CDS             complement(564..1409)
                     /locus_tag="JAM15_09360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6798457.1"
                     /translation="MIKVDDLSFSYTDRDFLQNINFEVEKGEILGFLGPSGAGKSTLQ
                     KILIGMITNYGGSVIVNGVESKRHSNKFYENIGVDFEFPSLYEKLTAIENLKYFGSLY
                     SKKLLSIDELLKSVGLENEANKRVSEYSKGMKSRLNFIKALLHNPDILFLDEPTSGLD
                     PSNSKVMKDIILSEKSKGKTIILTTHNMLDATELCDRVAFIVNGKISALDTPHNLIMS
                     KGAIKVRYTYFDNGEKTSECFLNNTANDKNLNMLIEKNKLLSIHSSEPTLNDIFIEIT
                     GRNLQ"
     gene            complement(1523..2113)
                     /locus_tag="JAM15_09365"
     CDS             complement(1523..2113)
                     /locus_tag="JAM15_09365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAT6798458.1"
                     /translation="MPKSYSDKEREYIIKRLKEEARLCMEQYGIRKTTVDELVKRVKI
                     PKGTFYLFFQSKEVLFFEVLRDIHDSIQKEILYEINRVDESITCEQLTDIFMKFYRMV
                     DSTSILNLMINGEFEILVRKLPDSIIEELFRHDDFEIGEIISCIPNAKNKDIESFSGA
                     FRAVFLTMLYKHEVGSNCFEDALRLMINGLVIQLME"
     gene            2402..2635
                     /locus_tag="JAM15_09370"
     CDS             2402..2635
                     /locus_tag="JAM15_09370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HAT6798459.1"
                     /translation="MATTTKNRFYDYVQENLNKYVEVHSYFSSCPLYGEIIEADSLSI
                     TLCSRYIDESNPTLNETYTLYLPLSSIISIRTL"
     gene            complement(2866..5253)
                     /locus_tag="JAM15_09375"
     CDS             complement(2866..5253)
                     /locus_tag="JAM15_09375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp13"
                     /protein_id="HAT6798460.1"
                     /translation="MKKFTSKKVARFVALFLISILVMSTIPVSADNSNTLNQIKKAEY
                     SDTYKQYLNDAKNGRTEKYNGIIPNPYQLEGTQIQSKGRTAPTSYDPRKLGLMTSVKN
                     QEDLGICWDFAAMATLESFLKLNNYGDYDLSEEHLRWWASDGEYGWSVNDMDGALNYE
                     AMGYLTSWSGPKLEKDIPYNGRVSKAQGAKKPTNMNTAPTVFNVTDAVCVSNDINSTK
                     NAILQYGAVTSGYYEDIKYQSDDQNSYYCPTKSFNTNHAISIVGWDDNYSKDNFNANI
                     RPSKNGAWLIKNSWGDYNSEGGYFWISYEDKTLMSDIDNFSIKGGKKPNDDEKMYQHD
                     YASIVPLISKKITAANVFDFNRGDETLKSVMFLTESIGAKYEVYYAPVVNGIPQENNM
                     KKLKEGTAQYSGYITVPIDSFNIPEGKGAIVVSIEGKNGESTIGSESNVPGYDTFKAK
                     ANLGESYIIDNTGKFFDINRDSNFYPCNFTIKAVTEKSSGESIPNESLIGSDRYETAI
                     KVSQNGFNSSENVVLVNGSSIVDALAATPFTSAINSPILLTQKEALNSKTKAEIQRLG
                     AKKVYLIGGENSISKEIEQQLKSLNISIERISGSDRYKTSLLLAQKLNGIKNVSQIAV
                     VNGVKGLADAISVGAAAAENNIPIILANEKSELQGADEFLNSLNIEKSYIIGGTASLS
                     NNLESKLKNPTRLSGSSRDETNSKIIDNFYKKDTLKNAFVVKNGIKNQNDLIDGLAVG
                     PLGAKTGSPVILVGDKLADSQKEVLKNKTLEKVTQVGGGANKNAFKELVKLKSAK"
     gene            complement(5445..6200)
                     /locus_tag="JAM15_09380"
     CDS             complement(5445..6200)
                     /locus_tag="JAM15_09380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyglutaryl-CoA dehydratase"
                     /protein_id="HAT6798461.1"
                     /translation="MFSIGVDSGSVATKGVLFDGEKIIKKIIIPTGWSPKNTSKQVYE
                     LLSSEIDKKDIKKVVGTGYGRGVMDFADKKVTEITCHTRGIYFLNKNIRTILDVGGQD
                     SKVINLDRDGNVFNFIMNDKCAAGTGRFLEITSNLLGSDIESIDTLAKGYEPVNISSM
                     CTVFAESEIVSLLAQNISTGEVAAGILKSIANKSTSMLARGEVIDEVAFTGGLAKSKE
                     LVKMIEEILGKKIFIAEDTQIIGALGAAVIGFR"
     gene            complement(6225..7376)
                     /locus_tag="JAM15_09385"
     CDS             complement(6225..7376)
                     /locus_tag="JAM15_09385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HAT6798462.1"
                     /translation="MTNLPKQFDSFNEARQKGFINAKELKESGKKMVGVFCTFTPVEI
                     PMAAGATVVGVCGVSEEPIPDAERVLPRNLCPLIKSSYGHAITDTCPYFYFSDLLIGE
                     TTCDGKKKMYEELAKVKPTYVMHLPNTSKGEFAYKLWKDEMIRLKEEVEKSLGVTITE
                     EDIRAAIKDKNEERELLKEFYALGKLQPSALTGLELHNVLYQAGFKFDRAELKHSLRK
                     VIDDMKERYEKGECPVQKDKPRILITGSPIGGISEKIVKTLEDAGASVVAYELCGAIR
                     SNDLLVDEEIEDVYDALTQKYINIGCSCMMNNDNRIELLDRIIDEYNVDAVIDVVLQA
                     CHTFNIESYRIREFVTKEKNKPFMSLETDYSKSDTEQLRTRFEAFVEML"
     gene            complement(7576..8316)
                     /locus_tag="JAM15_09390"
     CDS             complement(7576..8316)
                     /locus_tag="JAM15_09390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EcsC family protein"
                     /protein_id="HAT6798463.1"
                     /translation="MKDYEDVVYIKLVKKELEEWKKNILKKPSIFDKASKGIQNKFNG
                     VLPDKYHEIITSSIKVMTKTVLFGYKYATKPPLRNMSLEEREKLVLEKAKTYKTTAMI
                     EGAGTGAGGILLGLSDFPLLLGIKVKFLYDVASIYGYDVKDYRERIYILNILQLAFSS
                     QQHINKTFKLMNNWDEYVNSLPEDINDFDWRTFQQEYRDYLDLAKFLQLMPGIGAFVG
                     FYVNGKLIDKLCETAVSAYRLRIRELKL"
     gene            complement(8388..9377)
                     /locus_tag="JAM15_09395"
     CDS             complement(8388..9377)
                     /locus_tag="JAM15_09395"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HAT6798464.1"
                     /translation="MFENLPKIDLHCHLDGSVRVETMLDIAIKEKIDLPSNNMDEIKK
                     LAKVSFNCTSLDEYLEKFDLPLKVMQSKENLKRITFELLEDASRENVKYIEIRFAPLL
                     HTQKGMSVKNIIEGIIEGIREAESIYDIKGNLILGCMRTMTSKEALLVIEEGKSFVNK
                     GVVAVDLCGPEKEGFCKEYKDVFKLAREYGYKVTIHAGEAASGENVLDAINILKADRI
                     GHGVKIKDHKKAYNLVKDKKILLELCPTSNVQTKTVDSYEVHPFYTFYKDNLHVSINT
                     DNRTVSDINLSSELNVIFDTFKLGLEDYKIIYRNAVEASFADKETKEYLNSLI"
     gene            9637..10890
                     /locus_tag="JAM15_09400"
     CDS             9637..10890
                     /locus_tag="JAM15_09400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:glutamate symporter"
                     /protein_id="HAT6798465.1"
                     /translation="MITLSFDIVQTLTLSIFFFLIGNLLKNKVNFLNNFCIPAPVIGG
                     LLFCFLNLFFKYFNIADISISGNLMPNFITFFFTTIGLEISINLIKKGGSVLFRYWIL
                     CGVLAFCQNILAITISKIIKLEPLLGLMCGNVSMEGGHGYSAAFGLTIENLGIEGAVG
                     VGLSAATIGLIMGGILGCPVAKFLINKYKLKPSSNIGLSIPRYNRNLKRFGSKFFRNK
                     NRIKNNNFSETITPSVFLEQVLLIFICINTGEIISRCFYITFNILLPSVVTCMFSAVI
                     FRNLNDKINILELNFKLIDFLKELSLGIFLTLSLMNIDLFELSTLLPPILLIVTFQVI
                     FIILFSIFICFRVLGKDFDSAIIISGLIGHGIGATPNALANMSSLTQKYGDSPKAFLV
                     VPLVSGFLLDAISIPCILFFINILT"
     gene            10987..11211
                     /locus_tag="JAM15_09405"
     CDS             10987..11211
                     /locus_tag="JAM15_09405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HAT6798466.1"
                     /translation="MTVYNLKLGQKGIIDNIAGNEKLMKRLLALGLIDGTEVEVKKIA
                     PLNDPIVIRFRGFDLAIRKSDAKNINLKNN"
     gene            complement(11427..12734)
                     /gene="grdB"
                     /locus_tag="JAM15_09410"
     CDS             complement(11427..12734)
                     /gene="grdB"
                     /locus_tag="JAM15_09410"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(11685..11687),aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HAT6798467.1"
                     /translation="MSKIRVVHYINNFFAGIGGEEKADIPPEKRAGVVGPGIAFQSQF
                     NDDAEIISTVICGDTYFGENIESATQELLKMIKEESPDLFIAGPAFNAGRYGVACGTI
                     CKAVEEELNIPVVTGMYKENPGVDMFKLDLHIVSTGNSAASLRKIVPIMTKLGLKLIR
                     GEEIGPPEEEGYIIRGIRKNFFHELRGSERAIDMLVKKMKGESFETEYPMPEFDRVRP
                     MKPVKDLSKIKLALVTSGGIVPIDNPDKIESSSATKYGIYDLTDMDSMSNKEFTTIHG
                     GYDRAYVLENPNLVVPLDVVRELEKEGVIGELVDYFITTTGTGTSVGNSKRFGEEFSK
                     KLLEDDVDAVILTSTUGTCTRCGATMVKEIERAGIAVVHICTVVPISLTIGANRIVPA
                     VGIPYPLGNPMLGEEESKKIRKNIVLKALNALTEDIEEQTVFE"
     gene            complement(12820..14106)
                     /locus_tag="JAM15_09415"
     CDS             complement(12820..14106)
                     /locus_tag="JAM15_09415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007858867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HAT6798468.1"
                     /translation="MKLELGNIFIKNVEFGEKTEVKDGVLYISSEEIEKIVLEDERIV
                     SVNVELARPGESIRIAPVKDVIEPRVKIGDESKIFPGIINKVKTVGSGRTHVLLGACV
                     VTCGNIVGFQEGVIDMSGPTAKYTPFSKTNNICIVIKAKDGIDTHDYEEAARIAGLKI
                     GAYVGEAGREVEPDEVIVYETKPLLKQVKEYPDLPTVAYVHMLQSQGLLHDTYYYGVD
                     AKQIVPTFMYPTEIMDGAIISGNCVAPCDKVTTFHHLNNPVIHDLYKRHGKDLNFIGV
                     ILTNENVFLVDKERSSDMVAKLIEFLGVDGVLVTEEGYGNPDTDLMMNCRKCSEVGAN
                     VVLITDEFPGKDGKSQSIADATKEADAVVSCGQGNLVVHFPAMEKIIGTLDYVEMMIG
                     GYKGCLNEDGSMDAELQIIIASTIANGYNHLTARYY"
     gene            complement(14385..15707)
                     /locus_tag="JAM15_09420"
     CDS             complement(14385..15707)
                     /locus_tag="JAM15_09420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HAT6798469.1"
                     /translation="MKILLVDDELEYGVVMKKILQKKGYLVDIALSGEEAINIIKKDK
                     NYDLVLSDVMMKNMDGVQLLDRIKSINRDIEVILVTGYGSIENAVDAMKRGALSYFIK
                     SNPIENLLEEVEKVKASKISVSVQKNNFEFTLESKNRDFNNIIKIAKKAACKDVNILI
                     LGESGVGKDILARYIHSISPRKNEIFVPVNCCSFSENLLESELFGHEKGSFTGAVDSR
                     KGRFELSNKGTLFLDEIGDIPLNVQVKLLRTLEDKSIERIGSNKSIKVDFRLICAMNK
                     EPKVEISNGNIREDFFYRISTITITIPPLRKRREDLTTLIEFFLNKYQIEHDKKIHSI
                     DKEVKDFLLNYNYPGNIRELKNIINRLVVLSEEGNLSKDNLNLISNNVYIDDKISIRP
                     LREIRKEFECEYIEKVLSLCGNNISNTAKKLEISRRQLTNKISEYNIK"
     gene            complement(15707..17701)
                     /locus_tag="JAM15_09425"
     CDS             complement(15707..17701)
                     /locus_tag="JAM15_09425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HAT6798470.1"
                     /translation="MNKKKIVIIGIIYSFLVVFSLTNMYVNMEYNLNVFEYIKKSLPF
                     TEEEKKWLEKHKNLIYSSDQSSPPLRYKGKEDGQYKGIIVDLINSLSIQIGRDFYFKP
                     NNWWKESFVNSIDDSIKFFDLIPSKERANKFIFTDPIYTLSANILKDKKSQDINSYMD
                     LKGKTVAIPEGDYSINFLKQKIQDINILLTPDIKTGVNHLMSGKVDAVVGDEPVLRYY
                     INNYGLSNKYSVLSNPIYTKKAVLAVPKQYEELVSILNKGIFKLQKNGVYKDLKKKWY
                     STYNEVDDILYERGIVPSIYLFIGIILISIYVFYSYTYLLKIEIKRKTEQVIENKKTL
                     EATFNSITDIIMLVDENNNIVESNKVLYDFMGEMSYKIADLISMIKGVIKNTFSENTN
                     KTSEIEIHNKILKINTFPVEYKKNNTEYIVVLIKDITNEKIVEAKLLRENKMISIGQL
                     ASGVAHEIRNPLGIIRNNCYLLKDNVTMEEVNDCVKSIESNVDRASNIITNLLNFARI
                     SDDNLEHINIRNFIENIVKLQYKMLQLKNVEIKIDCEHNLVCYINGESLKHVFINLIS
                     NSIDAIHQDGKIIIYCYEKNHCLFIDFKDNGEGIKEDVLKDIFNPFYTTKPIGEGTGL
                     GLYITYNEIKKNNGDISVESKLGVGTCFHIKIPLNKEVTI"
     gene            complement(17788..19035)
                     /locus_tag="JAM15_09430"
     CDS             complement(17788..19035)
                     /locus_tag="JAM15_09430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HAT6798471.1"
                     /translation="MQITTFGAIFGLLIAIILIIKKFQAVYSLMLGAFIGGLVGGANI
                     TQTVDFMANGAMNISPSILRALASGVLAGSLIKTGAVDKISEQIVKIFGEKRALFSIA
                     ISTMVLAGVGVNLDVSIITVAPIGLYIGRKLNYSKLSILLAMLGGGKAGNIISPNPNT
                     IAVADNFSVNLSSVMMANIIPAIIGVVITVILASILINKGNKVQSYEILEQREDLPSL
                     FKSLCGPIIAIFLLFLGNVSSIVIDPMIALPIGGIVTLIVTGNLNNSREYLAFGLSKM
                     QGVCILLLGTGTIAGIIQMSELQQSTIGALQFLNMPQFLLAPVSGILMSLATASSTAG
                     ATIASSTFHDAIINGGLSPISGASIVNAGSSVFEQLPHGSLFHTSSGSINMDIGERFK
                     LIPYEALIGIVMTIISTSIQLVL"
     gene            19263..19808
                     /locus_tag="JAM15_09435"
     CDS             19263..19808
                     /locus_tag="JAM15_09435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAT6798472.1"
                     /translation="MNDLNLGEKIAEVRKKQNLSIRDLAKLADVTPSLLSQIERGLAN
                     PSVNSLKSIASSLNVPLFTFFVSEVDKKNLIVRHDNRKKVILPGSKEVIYEILIPDSS
                     GNLEFAIMDLAPNTSSCVDRITHNGDEIAYVLEGEVKLFMDDDEFTLSKGDSVKVPLG
                     TKHKWQNDSNSESKVIFAVIL"
     gene            19822..20508
                     /locus_tag="JAM15_09440"
     CDS             19822..20508
                     /locus_tag="JAM15_09440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="noncanonical pyrimidine nucleotidase, YjjG
                     family"
                     /protein_id="HAT6798473.1"
                     /translation="MKTYKFIFFDADDTLFDFKKSESHAFKKLLSEFDLEFNFENYIE
                     SYRNISDKLWLDLEKNIITLNELKLLRFELFANKISLDVDSETLSKMYLNFLGECTFL
                     IPGAIDILPYLKKKYTIVIITNGISAVQKKRLENSKIKGYIDGMVVSEELKISKPNPE
                     IFKYALKKFNCHDKSSALMIGDSLTSDILGGINSGIDTCWLNSNNSINYTNHMPTYEI
                     NTLIELKKLL"
     gene            complement(20632..21252)
                     /locus_tag="JAM15_09445"
     CDS             complement(20632..21252)
                     /locus_tag="JAM15_09445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798474.1"
                     /translation="MNYNSNKNKYLLKDINLDDIFIDKNIVLKFLGYGNRKAPYTISK
                     IVEREIRNINDILDIKIYISEVDIDKIPKECKKAFAVLYTIGDKIDIKMNDYMENCNM
                     MAGLALDKVGIVCLDCINEKIKMYLKGKYDSLKISHEIYPGDKDFEVERQKDIYNYVK
                     NKYNSIEIEINDYHQLSPIKSVAMLILMGDEENLESRCSKCPRKCF"
     gene            complement(21242..22264)
                     /locus_tag="JAM15_09450"
     CDS             complement(21242..22264)
                     /locus_tag="JAM15_09450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="HAT6798475.1"
                     /translation="MFSDMTLLQYINSEDRGFFLPDMGTNGLFLINKKAYEVYDSVDL
                     QLELAKTMDKYFESDFIYSFCDGITFCETLGLETLRPDYDFPSVLTHTITDRDKLRKL
                     DVPDPYTSGRMPLNIESLSVISKSIKKPLYESIQGPFTLAGQLAGATQLLRCIITDKK
                     FVEELLEFTTELVRRYAVAANKAGAKYISIAEPTSVTLSKDRFDEYIVKNLNKIYNEL
                     DCWKGMHICGDTRELLDNMLSCNIDAVSLDQILDYEEIAPMIPRDIVLIGNLDPIKLL
                     GRSKPDKIRRETLKLLKKMRGYDNFLCDFGCNCLNTTPVENLQAAIKAGRISYKELDR
                     IDIDEL"
     gene            complement(22265..22903)
                     /locus_tag="JAM15_09455"
     CDS             complement(22265..22903)
                     /locus_tag="JAM15_09455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-binding protein"
                     /protein_id="HAT6798476.1"
                     /translation="MDILDDIAECILNMGVDNIENLVKIAIDKNIDVEDIYEYGLNKG
                     MIGALDKFENKEYYLSEVIVCTDALNKGINLLKGTGKVKKKSKGVILMSVVEGDTHEI
                     GKNIVKVMVEATGYKVIDLGVNRKSEDIIEEAIKNNVDIIGLSSMMTTTMENMKSVID
                     ELNMIEIDKRPKVIIGGGPVSMEFAEEIGADGYSSNAPKAVKLINKLIGGEV"
     gene            complement(23021..24172)
                     /locus_tag="JAM15_09460"
     CDS             complement(23021..24172)
                     /locus_tag="JAM15_09460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004452985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAT6798477.1"
                     /translation="MELRPRSAKLEEFDKVIELINYVFRISRNHKPTMMEEFPLLLSK
                     NNIENMIIISEDDKVVSDVNYLIQDVSIQGNRLKVAAIGGVCTHPDYEKRGYSSKILD
                     KVEEKMFYDGVDIVIISGTRSLYSRRNCSLVKSFYKYTIKPEDVKIAYEIVEFDETNF
                     EKDDDLDKMLELYNQNSTRFIRTRDEFQKLLHAATIAWGPIGYKKVFIKENNNIIGYL
                     IIRTIKKEDSTVGEVAEIGLNSVNVENILKYVANKFGLEYLNYKVHVKNLKDQLKCNG
                     TESLDYQQGTMKIINFTKLCDSLRSYFSQYVDFELLKYMEFKQVENKYIIKYKEEELV
                     IENLDKLNKLFFEKNEEQYNEFKHLKNIYEFATKAFPVDFPWTANLNYQ"
     gene            24593..25405
                     /locus_tag="JAM15_09465"
     CDS             24593..25405
                     /locus_tag="JAM15_09465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mrp/NBP35 family ATP-binding protein"
                     /protein_id="HAT6798478.1"
                     /translation="MADCNSCPSKGNCNSQSNCSIENNPNNKFGKIIGVMSGKGGVGK
                     STVTALLANKLNKMGYKVGILDSDITGPSIPRLMGVKNVKAYSDGSYIYPVENSNNIK
                     VMSINLMIDDENEPVVWRGPLLGGVVKQFYTDVLWEELDYLLIDMPPGTGDVALTVMQ
                     SIPISGIVMVSVPQDLVSMIVSKAVNMAKKMNINVLGVIENMSYIQCPDCSKKIKLFE
                     GESTEKFLDDLDLELLGELPMTKEIIDITHNGVTEISDDLDSILTNVVEKIK"
     gene            complement(25494..25685)
                     /locus_tag="JAM15_09470"
     CDS             complement(25494..25685)
                     /locus_tag="JAM15_09470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798479.1"
                     /translation="MERLMELIERKFLKDVELLELEDIENVIECKMTQPYNAHYNEYL
                     VKVKNGDEVEEYFVYLKHR"
     gene            25991..26197
                     /locus_tag="JAM15_09475"
     CDS             25991..26197
                     /locus_tag="JAM15_09475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAT6798480.1"
                     /translation="MFKKKSGYTFTNFLNKVRVEKNKKYLLKKDLSILDVAVLIGFNS
                     QNYYSIIFKKFNNLTPIEYKNIYN"
     gene            26506..28125
                     /locus_tag="JAM15_09480"
     CDS             26506..28125
                     /locus_tag="JAM15_09480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HAT6798481.1"
                     /translation="MNIVISLIGGLGLFLYGMSLMGEGLQKSAGDKLKKIIELLTSNV
                     VMGVLVGTVVTGIIQSSSATTVMVVGFVNAGIMNLSQAIGVIMGANIGTTVTAQLVSF
                     NLEGIAPIALGIGILFYLFTSNQKTKHLSEILIGFGILFTGMEFMKDAVAPLAEYKAF
                     TDALLYFSKNPVLGILAGFAITGIVQSSSASMGMLIALASQGILPLSSALPILYGDNI
                     GTCVTSLLSSVGASRNARRAAVMHLSFNVIGTIIFMLVLNKPISAIVTHFDPTDTARQ
                     IANAHTLFNLTNVIILLPFSKYIVKLANRLIPIKETESEIVNNTKYLDERMFSTPSIA
                     LGNTVQEVVRMGHKATNSLEHSIAGFLNKSNEDINKAFESEKVVNKLQKDILNYLLKL
                     SKEPLRDDERFRTDLLFNTVNDIERVSDHAENIAELAMSVKEMNISFSDSAIREIYEI
                     YNKTITNFKDALIVLDVKDFELANKVLEVENEVNYLEKTFRNSHMIRLNNGNCTIDAG
                     VLYLDLLTNLERISDHSTNIVKQVLKLKQKI"
     gene            28499..28693
                     /locus_tag="JAM15_09485"
     CDS             28499..28693
                     /locus_tag="JAM15_09485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HAT6798482.1"
                     /translation="MINYMVEIIYSEKISEVENMLKIENIQYEFTSRDGFIFFGFYEM
                     TDAYRFETLCSDEKIRFKRI"
     gene            complement(29253..29576)
                     /locus_tag="JAM15_09490"
     CDS             complement(29253..29576)
                     /locus_tag="JAM15_09490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798483.1"
                     /translation="MATEIFTVKITPLEAQKMIKENLDADLVFSDSYNLGDDKFILIT
                     TFEKYYARNNSDAGLIVVYENTTGKTVIKATSTGSAIGILKIDWGAGGNLLKRVKNIL
                     ADYII"
     gene            complement(29621..29875)
                     /locus_tag="JAM15_09495"
     CDS             complement(29621..29875)
                     /locus_tag="JAM15_09495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798484.1"
                     /translation="MENKDFKLTICIFAFVIGVVVLFCCIGLGEFSAEHIIQQNGGIM
                     DTDQYNIYLDQSISQYRNFGSILALLGGIGILFDKYIRKY"
     gene            complement(30139..30420)
                     /locus_tag="JAM15_09500"
     CDS             complement(30139..30420)
                     /locus_tag="JAM15_09500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798485.1"
                     /translation="MASKQIPRNNLEKFLRIRVLSHTGDKIHIKLPVNFAKRMIENNA
                     LDLFNGKDDVVDGKKVTEILVKAFDYDLTGEVVHLERKNGDIIKVSIVQ"
     gene            30733..31542
                     /locus_tag="JAM15_09505"
     CDS             30733..31542
                     /locus_tag="JAM15_09505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6798486.1"
                     /translation="MNKIINNILNTCKQYTYILPHKLLRQYIAHYTISIPDTSIKENL
                     TLIPDASGCMIFKFDKKGIESAFWGATTKTTIVKNDIENVLFRVFVEFRPGGVYYLTG
                     LSQRESTDLKISLEDFNTLFSLEVNSIFERTSTIKELVEQLDMLFLSYLLKSNIVDMT
                     IPILENARKQNSIMSVKNISQISCYSERHLNRIFNNSLGMSVKSYLRLLRINLVLQEI
                     QNNKIPFATLAQDIGYYDQSHFINDFKSICGVNPTTYIKNLSDFYNEKYKF"
     gene            31584..31850
                     /locus_tag="JAM15_09510"
     CDS             31584..31850
                     /locus_tag="JAM15_09510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HAT6798487.1"
                     /translation="MIESRCGILCYECGYKEKVNCKGCTEIEKPFWGEQCPVKSCCED
                     KNLTHCGLCDTFPCEMLNQFAYDKEQGDDGKRISQCKKWAVLAL"
     gene            32132..32896
                     /locus_tag="JAM15_09515"
     CDS             32132..32896
                     /locus_tag="JAM15_09515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HAT6798488.1"
                     /translation="MNNYLKFATYQLIGFTSSIPRLIKIKKNPDKFSLKEKFEFMQKQ
                     AKKSLDIVNIELNIIGKETLPKEPLLFVVNHSSMLDSFILTGSVERPIGCVIADEPVW
                     RNIPIFKEWAKLLRCVYVNRKNNREGIKSIAQASQNILTGQSMAVFPEGDLTWIKEPN
                     SLVSEFRSGALKIAYKAKCPIVPLVIKNSKDTYEGYQPIGKINSVPVEVEFLEPIYDH
                     IENPRLKSSVLGENIKNKMINTIENFRKSNKTFKEF"
     gene            32959..33243
                     /locus_tag="JAM15_09520"
     CDS             32959..33243
                     /locus_tag="JAM15_09520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAT6798489.1"
                     /translation="MAKNTKQTTVHIDETLLKEVKRIGINENKSISQIINESIIDYIL
                     VYRENEDKEKNEHDKNLNETINEFKKEEEKRMQAKSAARAIAEAKKRVLY"
     gene            33391..33933
                     /locus_tag="JAM15_09525"
     CDS             33391..33933
                     /locus_tag="JAM15_09525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HAT6798490.1"
                     /translation="MKSYIALLRGINISGKNKIIMSELKASFVELGYSEVSTYLNSGN
                     VVFLSDVDDSKVISNTIRLMIKKQFELEIPVFIISQEELKDILNNAPNWWGDNNKEIY
                     DNLIFMFPDLSYDEFYDEVGNPKEEYEKVYHYKNAIFWSFSRKDYKKTNWWSKTASSN
                     VSDKITIRTANTVRKIVGMR"
     gene            complement(34096..35640)
                     /locus_tag="JAM15_09530"
     CDS             complement(34096..35640)
                     /locus_tag="JAM15_09530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HAT6798491.1"
                     /translation="MYRVGIDVGGTNTDACILDGELKVIHSVKVATTKDVETGVYNAL
                     KKVIDESKIDHSLIKYAMLGTTHCTNAIVERKRLNNVAMIRIGKPATTAILPFIDWPE
                     DLREKIELDSILVSGGYEFDGRKINELCKDEVVEFCNRIKGKVESVAISGVFAPVNKQ
                     QEEEVAKWVREILGDIPISLSNEIGNIGILERENGAILNSALSQVGKAVSLGFEKALK
                     DLGIDAQIYFSQNDGTLMNLEYTMKYPIFTIGCGITNSIRGASFLSKVKNAIVLDVGG
                     TTSDLGVLYNGFPRESSIPVTIGGVHTNFRMPDVLTIGLAGGTCVKGEKDNIKIGPES
                     VGYRITEDAIIFGGDTLTLSDVVTKLDMAFEDRKSNVENLDKEYCNEVYKKVILKLED
                     AVDQMKTSQDDVELVLTGGGSIIVPEKLKGISNVIRPPHYTAANAIGAALGQISGDVE
                     KVYSLDKMSREDAIEDAKKEAVNKALKAGAKEDTIEVLNIEDVPLAYLPGNALLIKVK
                     VVGDLI"
     gene            complement(35661..36740)
                     /locus_tag="JAM15_09535"
     CDS             complement(35661..36740)
                     /locus_tag="JAM15_09535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF917 domain-containing protein"
                     /protein_id="HAT6798492.1"
                     /translation="MRFLTEESVDKIAVGAAVLGTGGGGDPYVGKLVAKQAIKKYGPV
                     KVISLDELDDDALVVPVSGMGSPVITIEKLLSEVELTTPLEIMEKLLNRKVDVIIPIE
                     IGGINSLMPIAVAAKKGLPILDADSMGRAFPEAQMVTFYLEGYEASPAVMSDEKGNSA
                     ILYPVDGIWSERLARTLTVEMGGSSSISDYNLSGAQVKKAAIGNTLTIAETIGGFLLE
                     NKSDSKGAVENILKELCGYKLFEGKVIDIKRELKGGFTRGHAFFAGINEYDGEYSILF
                     QNENLIAKKGDTPLCITPDLIAVLDLETGFPITTERIKYGSRVMVVAFPCNEKWRTEK
                     GIETVGPGYFGYDVEYKTVEELQGK"
     gene            complement(36794..38083)
                     /locus_tag="JAM15_09540"
     CDS             complement(36794..38083)
                     /locus_tag="JAM15_09540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HAT6798493.1"
                     /translation="MEEEKINYALEQIPENQKRGWVAMFSVLVAIGVDLSSVILGAEL
                     AQSMPMKQAILSVIVGSFFSAILYTTCSLVGSSTSLSTSMITKYVFGEAGAKIFSLVI
                     GVSLLGWFGVQVGFFAQNAQIIIKDIFNLDVSMQILSLIGGLLMMSTAIYGYKAMEKL
                     SVYSVPFLLVLMMLTIFLAFRENGISVDDNMKSTMTFAGGVSLSMSIIIVGAIVSPDI
                     SRWAKSRRDCALSSFLGIQFGNAFMIIVSIVLVKCMGTSDIMRIFITLGIAIPGIIVL
                     TLAQWTTNTSNVYSASLSIALVLKKAPEKVLTIVLGIIATLLAVFGIYEGFIGFLNLL
                     GIVIAPVGGVYTAEYYIVKQELKGFDKGVLYKPIVKRSIVSWIIGILITYLSTYGFIT
                     LTTIAPLDGFIAGFVVQSIIGKVLCSTKNKQEIDKAV"
     misc_binding    complement(38246..38457)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
BASE COUNT        13100 a         6263 c         4287 g        14980 t
ORIGIN      
        1 atctccacta ataagagaaa tacatatatt aaaagggtac aaatttgcat atgattttgt
       61 gtcaagaagt acattgagta ttggtggaat aaagcatata atctcaatag gaatacttaa
      121 aacaataaac tgattcaaac tagatgcttt acttgcaagt atcaatccaa gcaaagaaaa
      181 tataatagaa gaaaaaaagg tacctatagt tgatattata atattatcta aatttaatgt
      241 aatagcaata aacatagcta caatactaga tattactcct aatgaaatta cctttgataa
      301 aatatactca gatactttta ctggagatac agctaaggaa tttaaaaccc tttgactttt
      361 ctcaagaagt acaatagctc ccataaaaaa caatcccatt gctgctgggt cagaataaat
      421 cataattata gctatttttt ctctcataaa agttggaaat acattgataa tacaaatata
      481 tataatactt aaaaaaagat ataaaaaata aaaaccatac ttaaattgaa actttatatc
      541 tcctaaaata agatttttta gcctcattgt aaattcctcc ctgttatctc aataaaaata
      601 tcatttaatg ttggttcact actatgtatt gataaaagtt tatttttctc aataagcata
      661 ttcaaatttt tatcattagc agtattgttc agaaaacatt cagaagtttt ttctccatta
      721 tcaaagtaag tatatctaac tttaatagct ccttttgaca taataagatt atgtggtgta
      781 tctaaagcag atattttacc atttacaatg aacgctactc tgtcacaaag ctctgttgca
      841 tctaacatgt tatgagttgt taaaataata gttttacctt tagatttttc tgataaaatt
      901 atatctttca taaccttgct atttgacggg tcaagaccac ttgttggttc atctaaaaat
      961 aaaatatctg gattatgtaa taaagctttt ataaaattta atctagattt catacctttt
     1021 gaatactcag ataccctttt atttgcttca ttttctagtc ctactgattt taataactca
     1081 tcaatagata gtagtttttt agaatataga gacccaaaat attttaaatt ttctattgca
     1141 gtcaactttt catataaact aggaaattca aaatcaactc ctatattttc ataaaattta
     1201 tttgagtgtc ttttactctc tactccattt acaatgacac ttcctccata attagttatc
     1261 attccaatta gaatcttttg taatgtagat tttcctgcac ctgatggtcc taaaaatcct
     1321 agtatttccc ctttttctac ttcaaagtta atattttgta aaaaatctct atctgtataa
     1381 ctaaatgata aatcatcaac tttaatcatt caatatcacc ctttcaaatt tttgactatt
     1441 ttgactatat ggtcaataaa atataatttt tttgtttgtt aataattttt aataaaagtt
     1501 attagcaaac aaaatttaaa ttctattcca taagttgtat aactaatccg tttatcatta
     1561 atcttaaagc atcttcaaaa caattacttc caacctcgtg cttatatagc atggtaagaa
     1621 aaactgctct aaatgctcca ctaaagcttt ctatgtcttt attttttgca tttggtatgc
     1681 aagatataat ctctccaatt tcaaagtcat catgtctaaa gagttcttca attatagaat
     1741 ctggtaactt tctcaccaat atctcaaatt ctccatttat catgagattt aaaattgaag
     1801 tactatcaac catcctatag aatttcataa atatatctgt caattgttca catgtaatac
     1861 tttcatctac tctatttatc tcatataaga tttctttttg tatagagtca tgtatatctc
     1921 tcaatacctc aaaaaagagc acttcttttg attgaaaaaa tagataaaaa gttccttttg
     1981 gtatttttac ccgttttaca agctcatcaa cagtagtttt tctaatacca tattgctcca
     2041 tacacaatct tgcttcttct ttaagtcttt ttattatata ctctctttct ttatcagaat
     2101 acgatttagg catctttttc ctccagtttg actaaaataa tttatatagt caatataata
     2161 ctttttctat ctaatgtcaa tagtattatt agtatattta aaaataagct taaaaacttt
     2221 cgaaaattct gaattttata tagcattttt tattatctag tgttataatt aagatataaa
     2281 taatatatta ttctaatttt catatctatt tgcttatttt ttaacttagt ttctaataga
     2341 agtactcata tttatctttt taaaagtttc aactttaata aaaaataaag gagttgattt
     2401 tatggctact actacaaaaa accgttttta cgattatgtt caagaaaact taaataaata
     2461 tgttgaagta cattcttact ttagcagttg tcctctatat ggtgaaatta tagaagcaga
     2521 tagcttatca attacacttt gctcaagata tatagatgaa tctaatccaa ctttaaatga
     2581 aacttacaca ttatatttac cattaagttc aataatatct attagaacac tataaaaagt
     2641 taattaaata tgggttattt atatataaaa tataagattt tctatatttc tatatatagt
     2701 aacccttttt tatgttttta aacttatact acataaattt aaagctgaaa acaaaacttt
     2761 acaatcattg attatcttat ttatcaataa tttaaagtaa ttattttcag cttttattaa
     2821 gataagttac taatacacac taatatatgt taatacttaa gtactctatt tagcactttt
     2881 taattttact aactctttaa atgcattttt atttgctcct ccaccaactt gagttacttt
     2941 ttctaaagtc ttatttttaa gaacttcttt ttggctatca gctaatttat caccaactaa
     3001 aattactggt gacccagttt ttgctcctaa aggaccaact gccaatccat ctattaaatc
     3061 attttgattc ttgattccat ttttaactac aaatgcattt tttaaagtat cttttttata
     3121 aaaattatct attatctttg aattagtttc gtctctacta ctaccagata atctagttgg
     3181 attttttaac ttactttcta gattatttga tagggatgct gttcctccaa taatataaga
     3241 tttctctata tttaatgaat ttagaaattc atcagctcct tgcaattcgc tcttttcatt
     3301 tgcaagtatg attggtatgt tattttctgc tgcagcagca cctacactaa ttgcatcagc
     3361 taatcctttc actccattta caactgctat ttgagataca ttttttatac catttaactt
     3421 ttgagctaat aataaacttg tcttgtatct atcacttcct gatattctct ctatcgatat
     3481 atttaagctt tttaattgtt gttcaatttc tttacttata gaattttctc cgcctattag
     3541 gtatactttc ttagcaccta atctctgtat ctcagcttta gtttttgaat ttaaagcttc
     3601 tttttgtgtc aataatattg gtgaatttat agcagatgta aaaggagttg ctgccaatgc
     3661 atctactatt gaactgccat ttactaaaac tacattttct gaagaattga aaccattttg
     3721 actaactttg atagcagttt catatctatc actaccaatt aaagactcat tcgggatact
     3781 ctcaccagaa gacttttctg taacagcttt tatagtaaaa ttacacggat agaagttact
     3841 atctctattt atatcaaaga attttccagt attatctatg atataacttt cacctaaatt
     3901 agcttttgct ttaaatgtat catatcctgg tacatttgac tcagaaccta tagttgactc
     3961 tccatttttc ccctctatac tgactacaat tgcacccttt ccttctggta tattaaaaga
     4021 atcaattgga actgttatgt atcctgaata ttgggcagta ccttctttta attttttcat
     4081 attgttttct tgaggtatac catttactac tggagcataa tatacttcat acttagctcc
     4141 tatactttca gttaagaaca ttacagattt tagagtttca tcgcctctat tgaaatcaaa
     4201 tacatttgca gctgttatct tttttgaaat taaaggtaca atacttgcat agtcatgttg
     4261 atacatcttc tcatcatcat ttggtttttt accacctttg attgaaaaat tatctatatc
     4321 agacataagt gtcttgtctt cataagatat ccagaaatat ccaccctcag aattataatc
     4381 tccccagcta ttttttatta accaagcacc attttttgat ggtctaatat ttgcattaaa
     4441 attatcttta gaatagttat catcccaacc cacaattgaa atagcatgat ttgtattaaa
     4501 actttttgtt ggacaataat atgaattttg gtcatcactt tgatatttaa tatcttcata
     4561 ataaccagat gttactgctc catactgtaa tatagcattt tttgtagaat ttatgtcatt
     4621 acttacacac acagcatctg tcacattaaa aacagtaggt gctgtattca tattagttgg
     4681 tttttttgct ccttgtgctt tagatactct accattgtat gggatatctt tttctaattt
     4741 aggacctgac caagatgtta aatatcccat agcttcataa tttaaagcac catccatatc
     4801 atttacagac catccatatt caccatctga agcccaccat cttaagtgct cttctgataa
     4861 atcgtagtct ccataattat ttaacttcaa gaaactttcc aaggttgcca ttgcagcaaa
     4921 atcccagcat attcctaaat cctcttgatt ttttactgat gtcataagac ctaattttct
     4981 agggtcataa gatgttggag ctgttcttcc tttactttga atttgagtac cttctaactg
     5041 atatggattt ggtataatcc cattatattt ttctgtacgt ccatttttag catcatttag
     5101 atattgttta taagtatcac tgtattctgc tttttttatc tgattcaatg tattgctatt
     5161 gtcagctgac acaggaattg ttgacattac taaaatagat attaaaaaca gtgcaacaaa
     5221 ccttgctact ttttttgaag taaatttttt cacgctttct cccccttatt ttgagctaat
     5281 ttttaaaatt ctaatgttat atatgactaa atatcaagta tttacaaata tacaatcatt
     5341 taaatcaatt ataccaaagt tttcctttat aaataaacaa aataaaataa aaaactgaac
     5401 ttatttatga taaattcagc ttttcatttt ctttttatat gtttttatct aaatcctatt
     5461 acagcagctc ctaaagctcc tattatttga gtatcttctg caataaaaat ttttttaccc
     5521 agtatttctt ctatcatttt tactagttct ttactttttg caagccctcc agtaaatgca
     5581 acttcatcta ttacctcacc tcttgctaac attgaggtgg atttatttgc aatagattta
     5641 agtatccctg ctgctacctc tccagtagaa atgttttgag ctagaagact tacaatttca
     5701 gactcagcaa aaactgtaca catactagat atattaactg gttcatatcc tttagctaat
     5761 gtatctatac tttcaatatc gcttcctaaa aggttagaag taatctctaa aaatcgacca
     5821 gttcctgcag cacacttatc attcattata aagttaaata catttccatc tctatctaaa
     5881 tttataactt tactatcttg accacctaca tctaaaatag tccttatgtt cttgtttaaa
     5941 aagtaaatac ctctagtatg acaagttatt tctgttactt tcttatcagc aaaatccatt
     6001 actccccttc cataacctgt acctaccacc ttttttatat cttttttgtc aatttcacta
     6061 cttagcaact catagacctg tttagatgta tttttagggc tccatccagt tggtataatt
     6121 attttcttaa taattttttc accatcaaat agcacaccct ttgttgccac tgaccctgag
     6181 tcaactccta tactaaacat agttcctcct acttttattt attcctacaa catctctaca
     6241 aacgcttcaa atctagttct taattgttca gtatctgatt ttgaataatc agtttcaaga
     6301 gacataaatg gcttattttt ttcttttgta acaaattctc ttattctata actttctata
     6361 ttaaatgtat gacatgcttg taaaactaca tctattacag catctacatt atattcatct
     6421 attattctat ctaataattc aatacgattg tcattattca tcatacaaga acaacctata
     6481 tttatatatt tttgtgttaa agcatcatat acatcttcta tttcttcatc aaccaataaa
     6541 tcgtttgatc taatagctcc acaaagttca tatgcaacga ctgatgcccc tgcatcttct
     6601 aaagttttaa ctattttttc gcttattcca ccaataggag aacctgttat caatattctt
     6661 ggcttatctt tttgaacagg acattcacct ttttcatatc tttctttcat atcatctata
     6721 acttttctta aagaatgttt aagttctgca cggtcaaatt taaaacctgc ttgatataaa
     6781 acattatgta actcaaggcc tgtaagtgca gatggttgta atttaccaag tgcataaaac
     6841 tcttttaaaa gttctctttc ttcattttta tcttttatag cagctcttat atcttcttca
     6901 gttatagtta cacctaaaga tttctcaacc tcttctttta accttatcat ttcatctttc
     6961 caaagtttat aggcaaattc tccttttgaa gtatttggca aatgcattac atatgttggc
     7021 ttaacttttg caagttcttc atacattttt ttcttaccat cacaagtggt ttctcctatc
     7081 aacaaatcag aaaaatagaa ataaggacag gtgtctgtta ttgcatgtcc atagcttgat
     7141 ttaattaaag gacaaagatt tcttggaagc accctttctg catcaggtat tggctcttca
     7201 ctaacaccgc atacacctac tacagttgct ccagctgcca ttggaatttc aactggagta
     7261 aatgtacaga aaactccaac catctttttc ccactttcct taagttcctt tgcatttata
     7321 aatccctttt gtctagcttc attgaagcta tcaaattgtt ttggcaaatt tgtcatgaaa
     7381 atattcctcc caattacttc tcttcgtaat tcaatttgta tcttaagcaa taaaaactaa
     7441 atttttccat taaaatacaa acctctacat tagattctat catgctttac cttttatcca
     7501 taattgtttt tatcaatgca aaattagata catatagata tattgtataa ctaatttttt
     7561 atgttataat ttctcttata acttaagctc tcgaatcctc aatctataag cagacacagc
     7621 agtttcacat aatttatcaa ttaattttcc attcacataa aatcctacaa atgctcctat
     7681 tccaggcatt agttgtaaaa acttagctaa atctaaataa tctctatact cttgttgaaa
     7741 tgttctccaa tcaaaatcat tgatgtcttc tggtagacta tttacatatt catcccagtt
     7801 attcatcaat ttaaaagttt tgtttatatg ctgttgacta gaaaaagcca actgtaatat
     7861 gtttaatata taaatccttt ctctataatc tttaacatca tatccatata ttgaagctac
     7921 atcatataaa aatttcactt taatacctaa aagcaaagga aaatcagata aacctaagag
     7981 gattcctcct gcccctgttc ctgccccttc aatcattgct gtggtcttgt aagttttagc
     8041 tttttctaaa actaattttt ctctttcttc taatgacata tttctaagtg gtggctttgt
     8101 agcatattta tatccaaaca gtacggtttt tgtcattact tttatagaag aagtaattat
     8161 ttcatgatat ttatctggca atactccatt aaatttattc tgtataccct ttgatgcttt
     8221 gtcaaatata gaaggtttct ttaatatatt tttcttccat tcttcaagtt cttttttgac
     8281 tagtttaata taaacaacat cttcataatc tttcacattt tttctcctaa tacaatgtat
     8341 ttttgtcaat ttaatagctt aatttaaagt ttaaatattt ttatctatta aattaaacta
     8401 ttcaaatact ctttagtttc tttatctgca aaactagctt ctactgcatt tctataaatt
     8461 attttatagt cttctaatcc tagtttaaaa gtatcaaata taacatttag ttctgaactt
     8521 aaatttatat ctgatacagt tctattatca gtatttatac ttacatgtaa attatcttta
     8581 taaaaagtat aaaatggatg tacctcataa gaatctactg tcttagtttg tacattacta
     8641 gttggacata attcaagcaa tattttttta tctttaacta aattatacgc ctttttatgg
     8701 tctttaattt ttaccccatg accaatccta tccgccttta aaatatttat agcatccaat
     8761 acattttctc cacttgcagc ttctcctgca tgtattgtaa ctttatatcc atattctctt
     8821 gctaatttaa aaacatcttt atattcctta caaaatccct ctttctctgg accacacaag
     8881 tctactgcta caacaccttt atttacaaat gatttccctt cttcaattac taataatgcc
     8941 tcttttgagg tcattgttct catacaacct aatattaaat tgccttttat atcataaata
     9001 ctttcagctt ctctaattcc ttcaattata ccctcaatta tatttttaac actcatacct
     9061 ttttgggtgt gaagtaatgg tgcaaatcta atttcaatat attttacatt ttctctactt
     9121 gcatcttcca aaagttcaaa agtaattctt tttaaatttt ccttagattg cattactttt
     9181 aagggtaaat caaatttttc taaatattca tctagtgaag tacaattaaa agaaaccttt
     9241 gctaattttt ttatttcatc catattattt gaaggtaaat ctattttctc tttaatagct
     9301 atatcaagca tggtttctac tctaacactt ccatctaagt ggcaatgtaa atctatctta
     9361 ggtaaatttt caaacatttt atcctcctac tgtacttata aataatacta tcaacagatt
     9421 tttaagtctt atttctatta tatcaatata ctacggtttt tcattctaaa aaagtcacat
     9481 ctcattaaaa tattttaatt taatttatga ctatctaatt atatatactg attcttttta
     9541 atatacattt attaatatac atttgataat aaaatttcaa tacataagaa tttaagttat
     9601 ataattaaaa ctttgaatta caaaggagga cttattttga ttaccttaag ttttgatata
     9661 gtgcaaacct tgacactatc tatattcttc tttttaattg gtaatttatt gaagaataaa
     9721 gttaactttt taaataattt ctgtatacct gcaccagtaa taggaggtct attattttgt
     9781 tttctaaatt tattttttaa atattttaat atagcagata tatctataag tggaaattta
     9841 atgccaaatt ttataacctt cttttttaca actataggac ttgaaataag cataaatctt
     9901 ataaagaaag gtggtagtgt attatttaga tattggattt tgtgtggagt attggcattt
     9961 tgtcaaaata tattagctat tacaatatca aagattataa aacttgaacc tcttttaggg
    10021 cttatgtgtg gaaatgtatc tatggaaggt ggtcatggtt attctgctgc atttggactt
    10081 acaatagaaa atctcggtat agaaggagca gttggggttg gattatctgc tgcaacaata
    10141 ggacttatta tgggtggtat attgggatgt cctgtagcta aatttctaat aaataaatat
    10201 aaattaaaac catcatcaaa tataggcttg tcgattccta gatataatag aaatctaaag
    10261 agatttggaa gtaaattttt tagaaataag aataggataa aaaataataa cttctccgaa
    10321 acaataacac catctgtatt tttggaacag gttcttctca tatttatttg tataaataca
    10381 ggagaaatta taagtagatg cttctatata acgtttaata tactattacc ctctgttgta
    10441 acttgtatgt tttcagctgt tatttttaga aatttaaatg ataagataaa tatattagaa
    10501 ttaaatttta aacttataga ttttttaaaa gaactttcat tgggaatttt tttaacttta
    10561 tcacttatga atatagattt atttgaatta tctacattat tacctcctat tctcttaata
    10621 gtaacttttc aagtaatctt tataatccta ttttcaatat ttatttgctt tagagtactt
    10681 ggaaaagatt ttgattctgc catcataata agtggtttga ttggacatgg aataggagct
    10741 actccgaacg ctttggcaaa tatgagttct ttgacacaaa aatatggtga ttctccaaaa
    10801 gcctttttgg ttgtaccatt agtaagtggt tttttgctag atgctattag tatcccatgt
    10861 atactatttt ttataaacat actaacttag tatgtttatt ttttgttata tattgacaat
    10921 ttactctttt tgttatatat tataaatata aagtttgata atgattttca ttaggaggtg
    10981 ttaataatga ctgtttacaa cttaaaactt ggacaaaagg gaattataga caatatagct
    11041 ggaaatgaaa aacttatgaa gagacttcta gccttaggac taatagatgg cactgaagtt
    11101 gaagtgaaaa agatagctcc tcttaatgac cctatagtga ttagatttag agggtttgac
    11161 ttagctatta gaaaatctga tgcaaaaaat ataaatttaa aaaataatta atatataata
    11221 aaaagagatt ttaaaatctc tttttttgtt tatgtataat cttctattta tttttttcat
    11281 tctttatact ttaattggct gttttactat aaatattttt attacttaat tgctttcttc
    11341 attccatcca tagcaaaaag atatcataaa ataattttca aaaactattt tatgatatct
    11401 ttttttattt ctatattata tttttattat tcaaatactg tttgttcttc tatatcctct
    11461 gttagtgcat ttaaagcttt taaaactata ttctttctaa tttttttact ttcctcttct
    11521 cctaacatag gatttccaag tggatatggt atccctactg ctggaacaat tctattagct
    11581 cctattgtaa gtgatattgg tactactgta catatatgaa caactgctat accagctctc
    11641 tcaatctctt ttaccatcgt tgccccacaa cgagtacaag tacctcatgt agaagttaaa
    11701 attacagcat ctacatcatc ttctaacaat ttcttagaaa actcttctcc aaatctctta
    11761 gaattgccaa cactcgttcc tgttcctgta gtagttataa aataatctac taattctcca
    11821 attacacctt ctttttcaag ctctctaact acatctaatg gtacaactaa atttggattt
    11881 tcaaggacat atgctctatc atacccccca tgtatagttg taaattcttt atttgacata
    11941 gaatccatat ctgttaaatc gtaaattcca tatttagtag cacttgaaga ttcaattttg
    12001 tctggattat caattggaac tatccctcca gaagttacta gggcaagttt tatcttagat
    12061 aaatctttaa caggtttcat aggtctaact ctatcaaatt caggcattgg atactcagtt
    12121 tcaaagcttt cccctttcat ctttttaacc aacatatcaa ttgctctttc agaccctcta
    12181 agttcatgga aaaaattttt tcttattcct ctaattatat atccttcctc ttcaggaggt
    12241 cctatttctt cacctctaat caatttaaga cctagtttcg tcattattgg aactatcttt
    12301 ctaagacttg ctgctgaatt tcctgtagac actatatgca aatctaattt aaacatatct
    12361 acacctggat tttctttata cattcctgta accacaggaa tatttaactc ttcttcaact
    12421 gccttacaaa tagtcccaca agctactcca tatctacctg cattaaatgc tggtcctgca
    12481 ataaataaat cagggctttc ttcttttatc atttttaaaa gttcttgagt tgcactctca
    12541 atattttcac caaaatacgt atctccgcaa attacagttg agattatctc tgcatcatca
    12601 ttaaattgac tctgaaatgc tattccaggt cctactacac cagccctttt ttctggcgga
    12661 atatctgctt tttcctctcc acctatacca gcaaagaaat tgtttatata atgaaccact
    12721 ctgattttac tcatctctta atcctccaaa tcactttata gttattacat caattagacc
    12781 aatgattaca tcaacagaac tttatattca aatacttatt taataatatc ttgctgtcaa
    12841 atgattatag ccatttgcta tagttgatgc tattataatt tgtagctctg catccatgct
    12901 tccgtcttca tttaagcatc ctttataccc acctatcatc atttcaacat aatctaaagt
    12961 tcctataatt ttttccattg ctgggaaatg aaccactaga tttccttgac cacaagaaac
    13021 aactgcatct gcttccttag tagcgtctgc tatagattga ctcttgccat cttttccagg
    13081 aaattcatcc gttatcaaaa ctacatttgc tccaacttca ctacattttc tacaattcat
    13141 cattaggtca gtatctggat tcccataacc ttcttctgtc actagaactc catcaactcc
    13201 taaaaattct attaatttag ctaccatatc agagcttctc tctttatcga ctaagaatac
    13261 gttctcatta gtcaaaataa ctcctataaa gtttaaatct tttccatgtc ttttatataa
    13321 gtcatgtata actggattat ttaaatgatg gaatgttgta accttatcac atggtgctac
    13381 acagtttcca gatattatag ctccatccat tatttcagtt ggatacataa atgtaggcac
    13441 tatctgttta gcatccaccc catagtaata agtgtcatgt aaaagtcctt gtgattgtaa
    13501 catgtgaaca tatgctactg ttggcaggtc tggatattct tttacttgtt ttaataatgg
    13561 ctttgtctca tatacaatga cttcatctgg ctcaacttct cttcctgcct cacctacata
    13621 tgcacctatt tttaatcctg caattctagc tgcttcttca taatcatgag tatctatacc
    13681 atcctttgct tttataacaa tacatatatt atttgttttt gaaaaaggcg tatatttagc
    13741 agtaggacca ctcatatcaa ttacgccttc ttgaaatcca actatatttc cacaagttac
    13801 aacacaagct cctaaaagta catgggttct tccacttcct acagtcttca ctttatttat
    13861 aattccagga aatattttgc tttcatctcc aattttaact ctaggctcta ttacatcttt
    13921 aactggagct attcttattg attcgccagg tcttgcaagt tcaacattta cacttacaat
    13981 cctttcatct tctaatacta tcttttctat ttcttcgcta ctaatatata gtactccatc
    14041 ttttacttct gtcttttctc caaattcaac attttttata aatatattcc ctagctctag
    14101 cttcatatga aaatccccct taatatattt aatcgcaatt aaaaatattt attacgttta
    14161 ttaatatata aagcattttc tatgccaatt atttaaaata tatattctat gtattaatgt
    14221 catagaaatt ttcattttta atttacacca gtattgaatt taccaataat tattgtaaat
    14281 attaattttt aaaattataa taaaaaaaga taaacagatt ttttctcttt atcttttaat
    14341 acagtttgag aaattttttt ctcacttaat gagaagtttt tttctcactt aatattatac
    14401 tctgatattt tattggttaa ctgtcttcta ctaatctcca attttttagc tgtatttgaa
    14461 atattatttc cacacaaaga taaaactttt tcaatatact cacattcaaa ctcttttctt
    14521 atttctctta aaggtctaat acttatttta tcatctatgt atacattatt tgatattaaa
    14581 tttaaattgt cttttgataa attgccttct tcacttaaaa ctacaagtct atttattata
    14641 ttttttaatt ctcttatatt tcctggataa ttgtaattta ataaaaaatc ctttacttcc
    14701 ttatcaatcg agtgtatctt tttatcatgt tcaatttggt acttatttaa gaaaaattct
    14761 ataagagtag ttaagtcttc tcttctcttt cttagtggtg gtatagttat tgttattgta
    14821 cttattctat aaaaaaaatc ttctcttata tttccatttg atatttccac ttttggttct
    14881 ttattcatag cacaaattaa cctaaagtca actttaatag atttattact tcctatcctc
    14941 tctatagatt tgtcctcaag tgtcctcaaa agttttacct gaacatttag aggtatatct
    15001 cctatttcat ccaaaaatag agttccttta ttcgaaagtt caaatctacc ttttctacta
    15061 tctactgctc ctgtaaaaga acctttttca tgaccaaaca actcagactc caatagattt
    15121 tctgaaaaag aacaacaatt tacaggtaca aatatctcat tctttcttgg acttatacta
    15181 tgtatatatc tagctaatat atcttttcct acaccagatt cccccaagat taatatatta
    15241 acatctttac aagcagcttt ttttgctatt tttatgatat tattaaaatc tctattttta
    15301 gattccaaag taaattcaaa attatttttt tgtacagaaa cagatatttt acttgccttt
    15361 accttttcaa cttcttctaa taaattttca atgggattac tttttataaa ataagataaa
    15421 gctcctcttt tcatagcatc aactgcattt tcaatacttc catatcctgt aactaatata
    15481 acctctatat ctctattaat agatttaatt ctatctaata actgtactcc atccatattt
    15541 ttcatcataa catcagataa aaccaaatca taatttttat cttttttaat tatatttata
    15601 gcttcttcac cacttagtgc tatatctaca agatagccct tcttttgtag aatttttttc
    15661 attaccactc catattctag ctcatcatca actaatagta ttttcattat atagtcacct
    15721 ctttatttaa tggaattttt atatgaaaac aagttccaac ccccaattta ctttcaacac
    15781 ttatatctcc attattcttt ttaatctcat tataagtaat atataaacct aaaccagttc
    15841 cctcaccaat tggttttgtt gtatagaagg gattaaatat gtcctttagg acatcttctt
    15901 ttattccttc accattatct ttaaaatcta taaataaaca atgatttttt tcataacagt
    15961 atataataat ttttccatct tgatgtattg catctattga attagaaatt aaatttataa
    16021 atacatgttt taacgattct ccatttatat agcatactaa attatgttca cagtcaattt
    16081 ttatttcaac attctttaac tgtaacattt tatattgaag tttcactata ttttcaataa
    16141 aatttcttat atttatatgt tctaaattat catctgatat tcttgcgaaa tttaacaagt
    16201 tggttattat attacttgcc ctatctacat tactttctat tgatttaaca caatcattca
    16261 cttcttccat tgtaacgtta tcttttaata gatagcaatt atttcttatt atacccaaag
    16321 gatttcttat ctcatgtgct accccagaag ctaattgtcc tatagatatc attttgtttt
    16381 ctctaagtaa tttcgcctct actatttttt cattagttat atctttaata agaactacta
    16441 tatactcagt attatttttt ttatactcta caggaaaagt gtttatcttt aaaattttat
    16501 tgtgtatttc tatttcacta gttttattag tattttcaga gaaggtattt ttaataacac
    16561 cttttatcat gctaatcaaa tctgctatct tataactcat ttcacccata aagtcatata
    16621 gtactttgtt cgattctact atattgttat tttcatctac aagcattatt atatctgtaa
    16681 tactattaaa agttgcctct aaagtttttt tattttctat tacctgttct gttttccttt
    16741 tgatttctat ctttaacaaa tatgtatagc tataaaaaac ataaattgat attaaaatta
    16801 tacctataaa aagataaata ctaggcacaa ttcctcgctc atacaatata tcatcaactt
    16861 cattatacgt agaataccat tttttcttta aatctttata tactccattt ttctgaagtt
    16921 taaaaatgcc tttatttaaa atactaacca gctcttcata ttgtttaggt acagcaagaa
    16981 ctgctttttt agtatatata ggattactta aaacactgta tttatttgaa agtccataat
    17041 tatttatata gtatcgcaat actggttcat caccaacaac tgcgtctact tttccagaca
    17101 ttaaatggtt gactccagtc tttatatctg gagtcaataa aatgtttata tcttgaattt
    17161 tttgctttaa aaaatttata gaataatcac cttctggaat tgctactgtt ttccccttta
    17221 aatccatgta actatttata tcttgggact ttttatcttt caatatattt gcactcaaag
    17281 tgtatattgg gtcagtaaat ataaatttat ttgccctttc ttttgatgga atcaagtcaa
    17341 aaaactttat actatcatct attgaattta caaaagattc tttccaccaa ttatttggtt
    17401 taaaataaaa atctctacca atttgaattg acagagaatt tattaaatca acaataattc
    17461 ccttatactg tccatcttcc ttacctttat atctcaaagg aggtgaactt tggtcagagc
    17521 tgtaaatcaa attcttgtgt ttttctaacc actttttttc ttcttctgta aatggaagtg
    17581 acttcttaat atattcaaat acatttaaat tatactccat atttacatac atatttgtaa
    17641 gtgaaaatac tactaaaaat gaataaataa tccctataat aacaatcttt tttttattca
    17701 ctttaaaact ccaatcttct tttttactat aataaattca atatttaata acaaaatcct
    17761 acttttttca ttaaatattt atatttatta taaaactaat tgaatagatg ttgaaattat
    17821 agtcattact attcctatca gtgcttcata tggaattaac ttaaatcttt cacctatatc
    17881 catgtttata ctacctgaac tagtatgaaa taatgagcca tgtggtaatt gctcgaatac
    17941 actagaccca gcatttacta ttgatgcacc tgaaatcggt gatagcccac catttattat
    18001 agcatcatga aaagtagatg atgctatagt agcaccagct gttgatgatg ctgttgctaa
    18061 tgacataagt atacctgaaa ctggtgccaa taaaaattgt ggcatattta aaaattgtaa
    18121 agcacctatt gtactctgtt gtaattcaga catctgtata attcctgcga tagtccctgt
    18181 tccaagtaat aatatgcata ccccttgcat cttagacaat ccaaaagcta aatattctct
    18241 tgaattgttc aagtttcctg tgacaattag agttacgatt cctcctattg gaagggctat
    18301 cattgggtct ataactatag aagatacatt tcctaaaaac aatagaaata tagctataat
    18361 tggaccacat aatgatttaa ataaacttgg taaatcttct ctttgctcta aaatttcata
    18421 tgattgtact ttatttcctt tatttattaa tatacttgct aaaataactg taataacaac
    18481 tccaataatt gctggaatta tatttgccat cataacacta gagagattga cagaaaaatt
    18541 atctgctact gctatagtat ttggatttgg tgatattata ttacctgctt taccccctcc
    18601 caacatagct aatagtattg acaatttaga ataatttaat tttctaccta tatataatcc
    18661 tataggtgct acagttatta tagatacatc caaatttacg cctactccag caagtaccat
    18721 agttgaaatg gcaatcgaaa ataaagccct cttttcacca aatattttta caatctgttc
    18781 tgatatttta tctactgctc ctgtttttat taaacttcca gctaatacac ctgatgccaa
    18841 agctctaaga attgatggtg atatattcat agctccattt gccataaaat ctacagtttg
    18901 tgttatattt gctcctccaa ctaatcctcc aataaatgct cctaacatta aactatatac
    18961 agcttgaaat ttttttataa ttaaaataat tgctattaat aaaccaaata tagctccaaa
    19021 agtcgttatt tgcataatgt cccctcctat cataaattaa ctatcttttg cttaatttta
    19081 tttaaatata ttttaagtat tctgtatcca ctttgtcaat tatattttaa tttatttaat
    19141 tatattgaac atagtttttt caaaacctaa ttctatatgt tataataatt tcatactaca
    19201 taatcatttt acttgattat tttaagttaa tattttttaa attaaaaaga gaggatattt
    19261 atatgaatga tttaaattta ggggaaaaaa tagctgaagt tcgaaaaaaa caaaacttaa
    19321 gtattcgaga tttagcaaaa ctagctgatg ttacaccatc attattgagc caaatagaac
    19381 gaggtcttgc taatccatct gtaaattcat taaaatctat agcctcttct ctaaacgttc
    19441 ctttatttac attttttgta tctgaagtag ataaaaaaaa cttgatagta agacatgata
    19501 atagaaaaaa agttatttta cctggaagca aagaagttat atatgagatt ttaattccag
    19561 actctagtgg taatttagaa tttgcaatta tggatttagc tccaaatact tcttcttgtg
    19621 ttgataggat tactcataat ggagatgaaa ttgcatatgt tttggaggga gaagttaaac
    19681 tttttatgga tgatgatgaa tttactttgt ccaaaggaga tagtgtaaaa gttcctttag
    19741 gaacaaagca taaatggcaa aatgactcaa atagtgaaag taaagtaatt tttgcagtca
    19801 tcttgtaaag gagtaaaaac catgaagaca tataaattta tattttttga tgcagatgat
    19861 actttatttg attttaagaa aagtgaatca catgctttta aaaaacttct atctgagttt
    19921 gatttagaat ttaattttga gaattatata gagtcatata gaaatataag tgataagctt
    19981 tggctcgacc ttgaaaaaaa tattataact ttgaatgaac ttaaattact tagatttgaa
    20041 ctttttgcaa ataaaatatc tttggatgtt gattctgaaa ctcttagcaa aatgtactta
    20101 aattttttag gtgaatgtac atttttaatt ccaggtgcaa tcgatatatt gccatatctt
    20161 aaaaaaaagt atactattgt tataataaca aatggaattt ctgcagttca aaagaaaaga
    20221 cttgaaaatt caaaaataaa aggatatatt gatggaatgg ttgtatctga agagttgaaa
    20281 atatcaaaac caaatcctga aatatttaaa tacgctctca aaaagtttaa ttgtcatgat
    20341 aaatcttctg ccttaatgat tggggatagc ttaacctctg atatcttagg tggaataaat
    20401 tcaggaatag atacttgttg gttaaattcc aataacagta taaattatac taatcatatg
    20461 ccaacttatg aaataaatac acttattgaa ttaaagaaac tactatagtt tgtaagtctg
    20521 ttcaaattaa atagaatatt actttgcaat aattttttta gtttatacat aaaatgacca
    20581 aaaaaattat tgcaatttat acacaaaaca aatcttagtc ttgaaaagta gctaaaagca
    20641 ttttctagga catttactac atcttgattc taaattttct tcatctccca ttaaaataag
    20701 cattgcaaca ctttttatgg gggatagttg atgataatca ttaatttcta tttctatact
    20761 attatattta ttttttacat agttataaat atccttttgt ctctctactt caaagtcttt
    20821 atctcctgga tatatttcat gcgatatttt gagactatca tactttcctt ttaaatacat
    20881 ttttattttc tcattaatac aatctaaaca tactatacct accttatcca atgccagccc
    20941 tgccatcata ttgcaatttt ccatatagtc attcatcttg atatcaattt tatcccctat
    21001 tgtatatagt acagcaaatg cttttttaca ctctttaggt attttatcaa tatcaacttc
    21061 acttatatat atcttgatat ctaaaatatc atttatattt cttatttctc tttcaacgat
    21121 tttactaatt gtatatggag cttttctatt tccatacccc aaaaacttta gcacaatatt
    21181 cttatctata aaaatatcat ctaaatttat atcctttaaa agatatttat ttttattact
    21241 attataattc atcaatatca atcctatcta attctttata actaattctt cctgctttta
    21301 tagctgcttg taaattttct actggagtgg tatttaagca gttacagcca aaatcacata
    21361 aaaagttatc atatcctctc atcttcttta acaattttag tgtctctctt ctaatcttat
    21421 ctggcttaga acgtccaaga agttttattg ggtctaaatt accaatcaac actatatctc
    21481 taggaatcat tggagcaatt tcttcatagt ctaaaatttg gtctaaactt actgcatcta
    21541 tattacaact tagcatatta tctaataatt ctctggtgtc tccacatata tgcatacctt
    21601 tccaacaatc aagttcattg tagattttat ttaaattttt tactatatat tcatcaaatc
    21661 tatctttact tagggttact gacgttggct ctgctattga aatatatttt gctcctgctt
    21721 tatttgcagc tacagcatat cttcttacca attcagttgt aaattccaac aattcttcta
    21781 caaatttttt atcagttatt atacatctta gaagttgagt agctccagct aattgacctg
    21841 caagtgtaaa tggaccttgt atcgattcat atagtggttt tttaatactt tttgatataa
    21901 ctgataagct ctctatattg agtggcatac gtccactcgt ataagggtct ggaacatcta
    21961 attttcttaa tttatctctg tcagttatag tatgtgtcaa tacacttgga aaatcataat
    22021 ctggtcttaa tgtctctaaa cccagagttt cacaaaatgt aatcccatca cagaatgagt
    22081 atataaaatc tgattcaaaa tacttgtcca tagtctttgc taattctaat tgcaaatcta
    22141 cgctatcata tacttcatat gcctttttat ttattaagaa caatccattt gtacccatat
    22201 caggcagaaa aaaacctcta tcttcactat ttatatactg aagtaaagtc atatctgaaa
    22261 acatttaaac ttcacctcct ataagtttgt ttattaattt aactgctttt ggagcatttg
    22321 aactgtatcc atctgctcct atttcttctg caaactccat acttacaggt cctccaccaa
    22381 ttattacttt tggtctttta tctatctcaa tcatattaag ctcgtctata accgatttca
    22441 tattttccat tgtagttgtc atcattgaag ataagcctat tatatctaca ttgtttttta
    22501 tagcttcttc tattatatct tcactttttc tatttacacc taagtcaata accttatatc
    22561 cagtggcttc caccattact tttacaatat tttttcctat ctcatgagta tctccttcta
    22621 ctacagacat cagaattact ccctttgatt ttttctttac ttttccagtt cccttcaaaa
    22681 gattaatacc tttatttaat gcatctgtgc atactataac ttctgaaaga tagtattcct
    22741 tattctcaaa cttatctaaa gctcctatca tacctttgtt taaaccatat tcataaatat
    22801 cttccacatc aatattttta tctatagcaa tttttactaa attctctata ttatctacac
    22861 ccatatttaa tatacattct gctatatcat caagtatgtc catataatac tcatcctttc
    22921 taattactta caaaattgct ttttcaatat ccaataattt ctcttattta acaaggacta
    22981 actctaggta tcaatcaatt ttatttaata tcatctaaaa ctattgataa tttaaatttg
    23041 cagtccatgg aaaatctaca ggaaatgcct ttgtagcaaa ttcatatata ttttttagat
    23101 gtttaaattc attgtactgt tcctcatttt tttcaaaaaa cagtttatta agcttatcca
    23161 aattttctat tacaagttct tcttctttgt atttaataat atatttattt tcaacttgtt
    23221 taaattccat gtattttagt aattcaaaat ctacatattg actaaaataa cttcttaaac
    23281 tatcacacaa cttagtaaaa tttattattt tcatagttcc ttgttgatag tccaaagatt
    23341 ctgtcccatt acatttcaac tggtctttaa gatttttcac atgtacttta taatttaaat
    23401 attctaatcc aaatttattt gcaacatatt tcaatatatt ttcaacattt acagagttta
    23461 accctatttc agcaacttct cctacagtag aatcttcttt ttttattgtt cttattatca
    23521 aatatcctat tatattatta ttttccttta taaatacctt cttgtaacca attggtcccc
    23581 aggcaatagt tgctgcatgc aatagttttt gaaactcatc tctcgttctt ataaatctag
    23641 tactattttg attatatagt tcaagcattt tatctaaatc atcatctttt tcaaaattag
    23701 tttcatcaaa ttcaactatt tcatatgcta tttttacatc ttcaggtttt attgtatatt
    23761 tataaaaact ctttaccaaa ctacaatttc ttctactgta tagacttctt gttcctgata
    23821 taattacaat atctacacca tcataaaaca ttttttcttc tactttatcc aatatcttag
    23881 atgaatagcc tctcttttca taatctggat gagtacatac tccacctata gctgcaacct
    23941 tcaatctatt tccttgaata gatacatctt gaattagata gtttacatca gaaaccactt
    24001 tatcatcttc tgatattata atcatatttt ctatattatt tttacttagt aaaagaggaa
    24061 attcttccat catagttggc ttatgatttc ttgatattct aaatacatag tttattaatt
    24121 ctattacttt atcaaattct tctaattttg cacttcttgg tcttaattcc attcatattc
    24181 ctccaaatat tatttaagat acttaaaact ctattatcta taataaaaca tttattacta
    24241 cagttctaat tatatctttt ttctttacaa tttttaattg tttttttagc aaatttttat
    24301 aaaatataaa cctaatttat agttaaactt ataaaataat ccgttatgta taatatatta
    24361 aaatattttc tatatattta tatgactaag ttctataact aaattaaaat aatcactttt
    24421 tcaagaatgt tataattttt ttattatatt ctttttgcta tagtctatga ataaatcaat
    24481 agaaaatctt ctaagttgct tttaaataat gactttatgg ttcaattgta ctaaaatagt
    24541 atatgtaggt tacaaataat ctaataaata ttaaagtttg gaggtaatag atatggcaga
    24601 ttgtaattca tgtccatcaa agggaaattg taatagtcaa tcaaattgtt ctattgaaaa
    24661 taaccctaac aataaatttg gaaaaataat tggtgttatg agtgggaagg gtggagttgg
    24721 aaaatcaact gtaactgctt tacttgctaa taagctaaac aaaatgggat ataaggttgg
    24781 tatattagat tcagatataa ctggaccaag tattcctaga cttatgggtg taaaaaatgt
    24841 aaaagcttat tctgatggct cttatattta ccctgtagaa aactcaaata acataaaagt
    24901 aatgtctata aaccttatga tagatgatga gaatgaacct gttgtttgga gaggaccttt
    24961 acttggagga gttgtaaagc aattttatac tgatgtactt tgggaagaat tagactattt
    25021 attaatagat atgcctcctg gtactggaga tgttgcctta acggttatgc aatctattcc
    25081 tataagtgga atagttatgg tttcagtacc tcaagatttg gtatctatga ttgtatcaaa
    25141 agctgttaat atggctaaaa aaatgaacat aaatgtcctt ggagttattg aaaatatgag
    25201 ttatatccaa tgtcctgatt gttctaaaaa aatcaagtta tttgaaggag aatctactga
    25261 aaagttttta gatgatttag acttagagct tttaggagaa cttcctatga ctaaagaaat
    25321 tatagatatt actcataatg gagttacaga aattagtgat gatttagatt caatattgac
    25381 taatgttgtt gaaaaaatta aataaataaa aattttataa ttttatattt atcaaaaaaa
    25441 gaggcttgta tttattttat aatcatacaa ataaatataa acctctttta tgtttatcta
    25501 tgttttaaat acacaaaata ttcttctact tcatctccat tttttacttt tactaagtat
    25561 tcattataat gagcattata tggctgtgtc attttgcatt ctattacatt ttctatgtct
    25621 tctaattcta aaagttctac atcctttaaa aattttcttt ctatgagttc cattaatctt
    25681 tccataatat atcctcactt cccctataat taagataaac tatatatcct cttaatacag
    25741 agtttatctg tttattatat tatatccaat atattacagt ttctaacatc attcataaat
    25801 tattttaaca aatagagatt gattttttaa taaatatgcc ttgataaaat gaaacataga
    25861 ccaactctta gttttatgta aagaaaactt aaagaaaact atagattata ttcacaaaaa
    25921 ctactcagaa gatataacag taagtaatat atgtaatgaa ttacaactta ataaaagtta
    25981 ttttttttct ttgtttaaga aaaaaagtgg atatactttt actaattttt taaataaagt
    26041 tagagttgaa aaaaacaaaa agtatctatt aaaaaaagac ttgtctattt tagacgttgc
    26101 tgtactaatt ggattcaata gtcaaaatta ctatagtata atttttaaaa agtttaataa
    26161 ccttacacca attgaatata aaaatattta taactaaaaa atatcattct aaaaggatgc
    26221 tattttttta catatttttt acaattatag ttaattcttt gttaaattga ttgtacataa
    26281 aatactaaaa atctaagttc aagtatttaa attgctatat atcataaatt ttctaaaatt
    26341 aacaacaact taaaaattta acattctctt aacgtatact taacaaaaca ttaatatttc
    26401 tattgacaaa atttgttatt ctatattatg gaaacaataa attttagtta ataaagttta
    26461 taattcagat aaaaaaatta ttaatttctt aagggaggaa atatcgtgaa tatagtaatt
    26521 agccttatcg gtggacttgg actttttctt tacggaatga gtttaatggg agaaggttta
    26581 caaaaatcag caggagacaa attaaaaaaa attattgaac tcttaacaag taatgttgtt
    26641 atgggtgtac tggtaggtac agtcgttaca ggtattatac aaagttcaag tgctactact
    26701 gttatggttg taggatttgt aaatgcaggt ataatgaatc taagtcaagc tattggtgta
    26761 ataatggggg caaatatagg tactacagtt actgctcaat tagtttcatt taatcttgaa
    26821 ggaattgcac caattgcttt aggtataggt attttattct atttatttac atcaaatcaa
    26881 aaaacaaagc atttatctga gatacttata ggttttggta tattatttac aggaatggag
    26941 tttatgaaag atgcagtagc tccacttgct gaatataaag cattcactga tgcactttta
    27001 tattttagta aaaatcctgt attaggtata ttggcaggat ttgccataac tggtattgtt
    27061 caaagttcaa gtgcatctat gggtatgtta atagcactag cttctcaagg aatacttcct
    27121 ctatcatctg ctttacctat tctttatgga gataatatag gtacttgtgt tacttcactt
    27181 ttatcaagtg ttggtgcaag tagaaatgct cgacgtgcag ctgtaatgca tttaagtttt
    27241 aatgtcattg gtacaataat atttatgctt gttttaaata aacctatatc agccatagtt
    27301 actcattttg acccaactga tacagctaga caaatagcaa atgcacatac tttatttaat
    27361 cttacaaatg ttataatatt attaccattt tctaaataca tagttaaatt agcaaataga
    27421 cttataccta ttaaagaaac tgaatcagaa atagtaaata atactaagta cttagatgaa
    27481 aggatgttta gcactccatc tatagcactt ggtaatactg tacaagaagt tgtaagaatg
    27541 ggtcataaag ctacaaactc tttggaacat tcaattgcag gatttttaaa taagagcaat
    27601 gaagatatta ataaagcttt tgagtcagaa aaagttgtca ataagttaca gaaagatata
    27661 ttgaactatt tgttaaaact ttctaaagaa cctcttagag acgatgaacg ctttagaaca
    27721 gatttgcttt ttaatactgt aaatgacatt gaaagagtct ctgaccatgc agaaaatata
    27781 gctgaattgg ccatgagtgt taaggaaatg aacattagtt tttctgatag tgcgataaga
    27841 gaaatatacg aaatatacaa taagacaatt actaatttta aggatgcctt aatagtttta
    27901 gatgttaaag attttgagtt agcaaataaa gttttagaag ttgaaaatga agtaaattat
    27961 ttagaaaaaa cttttagaaa ttcacatatg attagactaa ataatggaaa ttgtacaatt
    28021 gatgctggtg tactttatct tgacttactt actaatctag aaagaatttc tgaccactca
    28081 acaaatatag taaaacaagt attaaaactt aaacaaaaaa tatagtgatt atttttatat
    28141 ataatcttaa tcaatgagaa gtaagaagct atagataatg cttatatcat ttatggcttc
    28201 ttatttttta tgtaatactc aaatttttat agtattctct tattattaaa cagtttctgc
    28261 ctagaatatt ccatatatat atgacttctt tcataaaact tgaactgccc ataactaaag
    28321 tcacaagtat acataactat tttttaatca attataacca atatttattt tatttatctt
    28381 cattttaatt cttcattcaa taatgtaata agattatttt ttatttggat actattatat
    28441 catctaaata tgttattata tatttggata ttttcatatt aataggaggg attctacaat
    28501 gataaattat atggtagaaa ttatatatag cgaaaaaata agcgaagtag aaaacatgtt
    28561 gaaaattgaa aatatacaat atgaatttac ttctcgtgat ggctttatat tttttggttt
    28621 ttatgagatg acagacgcat atagatttga gactttatgt tcagatgaaa aaattcgatt
    28681 taaaagaata taataaataa aaaaagtaca tatttctaaa ctatttgttt ttcaaattta
    28741 ggttgtgttt taatgtagtg ttgatattat aaacaatttt aataataaaa aagtaggaat
    28801 attatattaa tatgctccta ctttttactc atatttatta atattattta tcaaaactac
    28861 cctacaaact ggaatttatc attctttcat aattttaaac tatcatattt aaaatatata
    28921 aaattctact tgatttttgt ataaacgtaa tatcaatcat tatccaattt aaaagtattt
    28981 tttagtaatt tccatttcat tttcttttaa catattaatt aaacttttat atgtaaatgg
    29041 tgtatttaca tattatttaa tatccaacaa ttatataaag aaatgtactc tttgccttat
    29101 aaagaattat aaagccaatt cgttttatta tattattttt ctttatacct taaaaacttt
    29161 accttcaaat tcttatttat ctatatatta taaaaatgtt cttaacctct tttacgagat
    29221 tttcttgaca tattatcagt tagataaaat aattaaataa tataatcagc aagtatgttt
    29281 tttactcttt taagtaaatt tccacctgca ccccaatcaa tttttaaaat tccaattgca
    29341 ctgcctgttg aagtagcttt aataactgtt tttcctgtgg tattttcata aactacgatt
    29401 aatcctgcat cactattatt tcttgcgtaa tacttctcaa aagttgtaat tagtataaat
    29461 ttatcatctc ctaaattata agaatcacta aaaactaaat ctgcatcaag attttctttt
    29521 atcatttttt gtgcctctaa gggtgtaatt tttacagtaa atatttctgt tgccattttt
    29581 tatctcctca taagaattta ttttagacaa aacataatct ctagtatttt ctgatatatt
    29641 tatcaaacaa tatccctatt cctcctaaca gagctaatat agaaccaaaa tttctatatt
    29701 gagaaataga ttggtctaga taaatattat attggtcagt atccatgatt ccaccatttt
    29761 gttgaataat atgctctgca ctaaattcac ctaaacctat acaacagaat aatactacta
    29821 ctccaattac aaaagcaaat atacatattg ttaatttaaa atccttattt tccatagtta
    29881 tccctctcat aagctaaatt tatttgatta tttttactag attttatatt actcttatta
    29941 tacaatacaa catatattta catctatttc caaaattgta acctttatag ttttatatat
    30001 ttaaattttt taaacaaaaa atacacatct ataaattata aatgtgtatt ctgcaccatt
    30061 actaataata tattatactt ttttacaaat ttctaattgt ttataactat tcaaaaataa
    30121 aattcatata aaataattct attgtacaat tgaaacttta ataatgtctc cattttttct
    30181 ctccaagtga actacttctc cagttaaatc atagtcaaat gccttaacta atatttcagt
    30241 aactttttta ccatctacta catcatcttt tccattaaat aaatccaaag cattattctc
    30301 aatcattctc tttgcaaaat ttacaggtaa ctttatatgt attttatcgc ctgtatgtga
    30361 taagactctt attcttaaaa acttttctaa attgtttctt ggtatttgtt ttgatgccat
    30421 gctattaaat cactctcctt tattttttat ttaataataa attttattct taaaaatatc
    30481 tttatatgta tttattatga aagtaacact attattttct aatcttgttt tatattcctt
    30541 cttctttaat atatttattt aataaatatc tatgatttat aataattgta tattttgaga
    30601 ttttacttta caattattgt atctaaattt aacaaaatat cttattagaa tatttcaatt
    30661 aaaacaaaac tggtttatta tataaaaaat aaattagtat acttatttta tatatatcag
    30721 gaggatatac ttatgaataa aataatcaat aacattttaa atacctgcaa acagtataca
    30781 tatattttgc cacataaatt gttaagacag tatatagcac actatacaat atctattcca
    30841 gatacaagta ttaaagaaaa tcttacatta atacctgatg ctagtggatg tatgatattt
    30901 aaatttgaca aaaaaggtat agaaagcgca ttctggggag ccacaacaaa aactactatt
    30961 gtaaaaaatg atatagaaaa tgtacttttt agagtattcg ttgagtttcg cccaggtgga
    31021 gtatattatt tgacaggtct ttctcaaaga gaatctacag atttaaaaat ttcacttgaa
    31081 gattttaaca cattatttag cttagaggtt aattccattt ttgaaagaac aagtactata
    31141 aaagaattag tagaacaatt agatatgtta ttcttatcat acttattgaa atcaaatata
    31201 gtagatatga ctataccaat tcttgaaaat gctagaaaac aaaactctat tatgtctgtt
    31261 aaaaacattt cacaaattag ttgttatagt gaacgacatt taaatagaat ttttaataat
    31321 tctcttggta tgagtgttaa atcatacctt agattacttc gtataaacct tgtattacaa
    31381 gaaatacaaa ataataaaat accatttgca actttagcac aagatattgg ttattacgac
    31441 caatctcatt ttataaatga ttttaaatct atttgtggtg ttaatccaac aacctatata
    31501 aaaaatttgt ccgattttta caatgaaaag tataaatttt gatatacaat catataaaat
    31561 ttatatttaa ggagtgactt aaaatgatag aatcaagatg tggaatttta tgttatgaat
    31621 gtggatacaa ggaaaaagtc aattgtaaag gttgtacaga gattgagaaa ccattttggg
    31681 gtgaacaatg tcctgtaaaa tcttgttgtg aagataaaaa ccttacacat tgtggtctat
    31741 gtgatacatt tccatgtgaa atgcttaatc aatttgcata tgacaaagaa caaggtgatg
    31801 atggcaaaag aatttctcag tgcaaaaaat gggctgtact agccttataa tatactctct
    31861 tgttataaaa taagtttttg taaggtaaat tttttaaact gttgtagaaa tttctgcaac
    31921 agtttttata attaaattta aaggttattt aattaaatta atagaatagt aatttattga
    31981 taaaatctga ttactaaaat tagaaatata aaatctcaat ctctgtctat ttaaaatata
    32041 tgttacaaaa ttgaattaaa atagacttaa attttatttt atgttaaaat ctttacagta
    32101 ataaataatt ttattttaag gagataattt tatgaataat tacttaaaat ttgctacata
    32161 tcaacttata ggttttacat cttctatacc taggcttatt aaaattaaaa agaatcctga
    32221 taaatttagc ttaaaggaaa aatttgaatt tatgcaaaaa caagctaaaa aatctttaga
    32281 tatagtgaac atagagctta atataattgg taaggaaaca ctgccaaaag aaccacttct
    32341 atttgttgta aatcattcta gtatgcttga cagcttcata ctaacaggaa gtgtagaaag
    32401 accaattgga tgtgtaattg cagatgaacc agtttggaga aatataccta tatttaaaga
    32461 atgggcaaaa ttactaagat gtgtatatgt aaacagaaaa aacaatcgtg agggtataaa
    32521 gagtatagcc caagcctctc aaaatatact tacaggtcaa agtatggcag tgtttccaga
    32581 aggagattta acatggatta aagaaccaaa ttcattggtt tcggagttta gaagtggagc
    32641 tttaaagata gcatataaag caaaatgccc tattgttcca ctcgtaataa aaaattcaaa
    32701 agatacttat gaaggatacc aacctattgg taaaattaac tctgttcctg tcgaagtcga
    32761 atttttagaa ccaatttatg accatataga aaatcctaga ctaaagtctt ctgtactagg
    32821 tgaaaatata aaaaataaga tgataaatac aatagaaaat tttagaaaat caaataaaac
    32881 atttaaagaa ttttaatatt aaaatttatt gactaaaaaa aattttaatg ttagaatttt
    32941 ttttaagagg tgattaaggt ggcaaaaaat acaaagcaaa caacggttca tattgatgag
    33001 actctactta aggaagttaa gagaatagga attaatgaaa ataaaagtat atctcagata
    33061 ataaacgaat caataataga ttatatatta gtatacagag aaaacgaaga taaagaaaaa
    33121 aatgaacatg ataagaatct aaatgaaaca ataaatgaat ttaaaaaaga agaagaaaaa
    33181 agaatgcaag caaaaagtgc tgctagagct atagcagaag caaaaaaacg agttctttac
    33241 taagaaaaac aaaaatcggt acaaattaag caccgatttt tttatattaa aaaaattaca
    33301 tatgaagaag ttttgaaaga attataaaag atgcaaattc cagtttgtac tacatagaaa
    33361 aatgtgaatg tttagaggtg aaattattat atgaaaagtt atatcgcatt attaagaggt
    33421 atcaatataa gtggtaagaa caagataatt atgtctgaat taaaagcaag ctttgtagaa
    33481 cttggttatt cagaagtttc tacatacctt aatagtggta atgttgtctt tttaagtgat
    33541 gtagatgaca gcaaggttat ctcaaataca ataagattaa tgataaaaaa acagtttgaa
    33601 ttggaaatac cagtttttat tatttcacaa gaggagttaa aagatatact aaataatgct
    33661 cctaattggt ggggagataa caacaaagaa atatatgata atcttatttt tatgtttcct
    33721 gacttatctt atgacgagtt ttatgatgag gttggaaatc ctaaagaaga gtatgaaaaa
    33781 gtatatcatt ataaaaatgc tatcttttgg tcttttagtc gtaaagatta taaaaagaca
    33841 aattggtggt caaagactgc cagttcaaat gtaagtgata agattacaat tcgtacagca
    33901 aatacggtaa gaaaaatagt tggaatgcga taaaagataa caaacagccg ataaacctca
    33961 aaaaataggt atatatcggc tgtttggaaa cttataagaa tatagtcaaa agttatgctg
    34021 tttttattga taaaataagt ttaaaaatga gtccagaaat atttatataa ttctggaaat
    34081 acttatattt attctttaaa ttaaatcacc aacaactttt acttttataa gaagtgcatt
    34141 accaggaagg tatgcaagtg gaacatcttc tatatttaat acttctatag tatcttcttt
    34201 agcaccagct tttagagctt tatttacagc ctcttttttt gcatcttcta tggcatcttc
    34261 tctcgacatt ttatctaaac tgtatacttt ttctacatct ccacttattt gtcctaaagc
    34321 tgcaccaata gcatttgcag cagtataatg aggaggtctt ataacattgc ttatgccttt
    34381 tagtttttca ggaacaatta tacttcctcc accagttaaa accaattcaa catcatcttg
    34441 actagtcttc atttggtcta cagcatcttc taattttaaa ataaccttct tatatacctc
    34501 attacaatac tctttatcta agttttcaac attgcttttt ctatcttcaa acgccatatc
    34561 taattttgta acaacatctg ataaagttag agtgtctcca ccaaatatta ttgcatcttc
    34621 agttattcta tatcccacac tttcaggacc tatctttata ttatcttttt cgccttttac
    34681 acatgtacca ccagcaagac caatagttaa aacatctggc attctaaagt ttgtatgtac
    34741 tcctccaatt gtaactggaa tagatgattc tctagggaat ccattatata gtacacccaa
    34801 gtcgcttgta gttccaccaa catctaatac tattgcattt tttacttttg ataagaagga
    34861 agctcctctt atagaatttg ttattccaca tccaattgta aaaattgggt atttcattgt
    34921 atactctaaa ttcattaatg ttccatcatt ttgactgaaa tatatttgag catctatacc
    34981 taagtcttta agtgcttttt caaatcctaa agatacagct ttacctactt gagacaatgc
    35041 agaatttaaa atagctccat tttctctttc taatatacct atattaccta tttcatttga
    35101 taaagatata ggaatatccc ctaaaatttc tctaacccat tttgcaactt cttcttcttg
    35161 ttgtttattt actggagcaa atactccact tattgcaaca ctttccactt tgccttttat
    35221 tctattgcaa aactctacaa cttcatcttt acaaagttca tttatctttc taccatcaaa
    35281 ctcatatcca ccagatacca atattgaatc taattctatt ttttctctta agtcttctgg
    35341 ccaatctata aatggaagaa tggcagtagt ggccggcttt cctattctta tcatagctac
    35401 attattaagt ctttttcttt ctacaatagc atttgtacaa tgagttgtac caagcatagc
    35461 atattttatt aatgaatggt caatcttact ttcatctata acttttttta aggcattgta
    35521 aacaccagtt tcaacatctt ttgtagttgc caccttaact gaatgaatta cttttaattc
    35581 cccatccagt atacaagcat ctgtatttgt tcctccaacg tcaattccta cacgatacat
    35641 taaaatttcc tcctaaactt ttattttcct tgtaattctt ctactgtttt atattccaca
    35701 tcatatccaa agtatccagg tccaactgtc tcaattcctt tttctgttct ccacttttca
    35761 ttacaaggaa aagctactac cataacacga gagccatatt ttattctctc tgtagttatt
    35821 ggaaatccag tttctaaatc taatactgct attaaatctg gtgtaataca aagtggtgta
    35881 tcaccttttt tggcaattaa attctcattt tggaataata tagaatactc tccatcatac
    35941 tcattaatcc cagcaaaaaa ggcatgtcct ctagtaaatc cacctttcaa ctctctctta
    36001 atatcaatta cttttccttc aaataacttg tatccacaca attcttttag tatattctca
    36061 acagcacctt ttgaatcaga tttattttca agtaaaaacc ctcctatagt ttcagctatt
    36121 gtaagagtat tacctatagc agctttttta acttgagctc cacttaaatt atagtcacta
    36181 atagaagaac ttcctcccat ttctacagtt aaagttctag ctaatctttc tgaccaaatt
    36241 ccatccacag gataaaggat ggcagaatta cctttttcat cagacattac ggcaggagat
    36301 gcctcatatc cttcaagata aaaagttacc atttgagctt cagggaaagc tctacccata
    36361 gaatctgcat ctaagatagg aagtcctttt ttagcagcaa ctgctatagg cataagtgag
    36421 tttatccctc ctatttctat aggaattata acatccactt ttctatttaa taatttctcc
    36481 attatttcta aaggggtagt taactctact tctgaaagta atttttctat tgtaattaca
    36541 ggagaaccca taccagatac tggaactacc aaagcatcat catcaagttc atctaaactt
    36601 attactttta caggaccata ctttttaatg gcttgttttg caaccaattt acctacatat
    36661 gggtcacctc cacctccagt tccaagcact gctgcaccaa ctgctatttt atctacactt
    36721 tcttctgtta aaaatctcat gttactttct cctcatattt ctaatttatt ttatacttta
    36781 taaacaaatt tctttatact gctttgtcta tttcttgctt attttttgtt gaacaaagca
    36841 cttttccaat aatagattgt actacaaacc ctgctataaa accatctaaa ggtgctatag
    36901 tagtaagagt tataaatcca tatgttgaaa ggtaagttat taatatacca attatccaag
    36961 acactattga acgtttaact attggtttat ataatactcc tttatcaaag cctttaagtt
    37021 cttgctttac tatgtaatat tctgctgtat atacaccacc aacaggtgca attacaattc
    37081 caagtaaatt taaaaatcct ataaaacctt catatattcc aaatacagcc aataatgttg
    37141 ctataatacc aaggactata gttaatactt tctcaggagc cttcttaagt acaagagcta
    37201 tacttaatga tgctgaatat acattacttg tatttgtagt ccattgtgct aatgtaagta
    37261 ctattatacc tggtatagca attcctaatg taataaaaat tctcataata tctgaagttc
    37321 ccatacattt tactaatact atcgaaacta ttatcataaa agcatttcca aattgtattc
    37381 ccaaaaagct tgaaagagca cagtctcttc tacttttagc ccaacgactt atatcaggag
    37441 atacaattgc accaactatt attatactca ttgacagaga aactccacct gcaaatgtca
    37501 tagtagattt catattatca tcaactgaaa ttccattttc tctaaaagct aagaatatag
    37561 ttagcatcat aagaactaat aaaaatggta ctgaatacac actcaacttc tccatggcct
    37621 tatatccata aattgcagta ctcatcatca agagaccacc tattaggctt aaaatctgca
    37681 tactgacatc taaattaaat atatctttta ttattatctg tgcattttgt gcaaagaaac
    37741 ctacttgaac tccaaaccaa cctaatagag aaacccctat aactagagaa aatatttttg
    37801 ctccagcttc tccaaataca tactttgtta tcatagatgt agataaactt gtagatgaac
    37861 caaccaaaga gcatgtagta tacaaaattg cagaaaaaaa tgaaccaaca attactgaca
    37921 atattgcttg tttcattggc atactctgtg ccaactcagc gcctaaaata acagatgata
    37981 aatccacacc tattgctact aaaactgaaa acatagctac ccaaccacgt ttttgattct
    38041 ctggaatctg ttccagagca tagttaattt tttcttcttc cattttcatc cctccattta
    38101 aatcgtaaaa ctactgacct tagcatattt tacaattttc taatttataa atttattaac
    38161 tatcatattt ttataatttt catttaatat atagttttaa attttctgaa ataagtttat
    38221 aataaaaaac gcctcttgga aaaatccaag agacgaatat aaatccgtgt taccactctt
    38281 attagtaaaa attaatttta ctcactcatt ttcttaaggc gaattaaacc actattctaa
    38341 cataattaca atagtattct ccaaagtcct tttcacataa attccaatat tagttctcag
    38401 ccaaatctaa ctctctgtaa aattccttta tgctactttc ttcttctacg aatatataat
    38461 attgatttgt agttaattta tgatttatat cataatatat atgcaatatt ttgtcaactt
    38521 aaaaagtcaa ttacttgcat tttttagttt tatatgtaaa ttttcatact attactatat
    38581 ttatataatg tattttttta aatttcatca aaatatattt tttttatact
//
LOCUS       DACTZW010000036        36347 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.036, whole genome shotgun sequence.
ACCESSION   DACTZW010000036 DACTZW010000000
VERSION     DACTZW010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 36347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36347
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.036"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            110..2011
                     /gene="cooS"
                     /locus_tag="JAM15_09545"
     CDS             110..2011
                     /gene="cooS"
                     /locus_tag="JAM15_09545"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HAT6798494.1"
                     /translation="MACNTCKMCESADKKLESFVASKDVETAFHRTEDQKVKCGFGLQ
                     GVCCRLCSNGPCRVTPKSPRGICGADADTIVARNFLRAVASGAACYLHVVENTAKNLK
                     NVGITKGVVKGEKTLNQLAEMFGIESDEKYDKCIKVADKVINDLYKSRDDKMELVEKI
                     AYAPRVKKWKELGIMPGGAKSEVFDAIVKSSTNLNSDPVDMLVNCLNLGISTGLYGLT
                     LTNLLNDVMLGEPVIRMAPVGFNVIDPDYINIMITGHQHSTFANFQDRLKDEDVIKLA
                     QSVGAKGFKLVGCTCVGQDLQLRGEHYQEVFAGHAGNNFTSEAVLSTGAIDIVLSEFN
                     CTIPGLEPIADKYKVKMVCLDDVAKKANAEYIGLDRSKLDELSNTLIEKALESYKERR
                     GSIEIDIPKDHGFEQSLTGVSEKNLKAFLGDSWKPLINLIAEGKIKGVAAVVGCSNMT
                     AGGHDVNTVELTKELIKKDIIVLSAGCSTGGLENVGLMSPGAEELAGENLKEVCKTLG
                     IPPVLNFGPCLAIGRLEIVATELAAELGIDLPQLPLVLSAPQWLEEQALADGAFGLAL
                     GLPLHLALPPFITGGKLVTEVLTEKLKDLTGGHVIVNPDPKSSANQLEEIIIDRRKNL
                     GLKDVECNA"
     gene            2004..2477
                     /locus_tag="JAM15_09550"
     CDS             2004..2477
                     /locus_tag="JAM15_09550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HAT6798495.1"
                     /translation="MHRIFINKDLCTGCKSCVLACMLKHNKDYDMYTLDLENIDNDSR
                     GHIELDSKHNNPVPILCRHCDEPECVLACMSGAMHKDSESGIVSYDEEKCGSCYMCVM
                     SCPYGLLKPDDRSKQNILKCDLCKDEEYPRCVANCPSGAIELQKEENDELCSVRG"
     gene            2452..3678
                     /locus_tag="JAM15_09555"
     CDS             2452..3678
                     /locus_tag="JAM15_09555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAT6798496.1"
                     /translation="MNYVVLGASAAGINAVKTLRELDKDSNIVVISKDENVYSRCMLH
                     HVISEHRTLKQINFVDEDFMEQNNVKWIAGKTVKGIDINKKVVQTEDITVNYDKLLIA
                     TGASSAIPPIKNLRDGNFVYSVRNIDDIYKIKEKAQNSKNVVIIGAGLVGIDALVGLF
                     KYEQLNISVAFMEKYILDRQLDEYTASVYENKFKEKGVKFYPSASIQEIVLDNSKNVT
                     GVAFSNGEVLDADMVIVATGVKPNADFLDGTGIEYDRGIIIDDMCQTTQKDIYAAGDV
                     VGKNAIWPLAVKQGIVAAYNMVGKDKKIEDEFAFKNSMNFMDISTISIGMNTPVDHSY
                     KVLTRHGINDYKKFVFKDNVIYGAVIQGDISYVGVLTYLIKNKVEIYDLENRIFDVCY
                     ADFFNIKENGEFCYSV"
     gene            complement(3817..5004)
                     /locus_tag="JAM15_09560"
     CDS             complement(3817..5004)
                     /locus_tag="JAM15_09560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAT6798497.1"
                     /translation="MNITKNFLKDYLEKFGETPFLVRLKDEEEFLIGEGSPQFKVIVN
                     NDISKSELLKSTSLALGEAYINRDIEVEGDLFLTLNLLLKQIDKFNIDNSAVKHLLHS
                     SNSMRHQKKEIHAHYDIGNDFYSLWLDKTLSYSCAYFRNDNDTLYDAQVNKVHHILTK
                     LNLEEGMSLLDIGCGWGFLLIEAAKKYKIHGVGITLSEEQFKEFNARIKEENLQDYLE
                     VRLMDYRELKKSDLMFDRVVSVGMLEHVGRENYELFIKNVNAVLKDGGLFLLHYISGL
                     QESYGDPWIKKYIFPGGVIPSLREMIHICSDYKYHTIDVESLRLHYVKTLLYWQKSFS
                     ENLPKIKEMFDDKFIRMWDLYLCSCAAAFNTGIIDIHQILFTKGIKNDLPLTREYMYN
                     CSK"
     gene            5277..6101
                     /locus_tag="JAM15_09565"
     CDS             5277..6101
                     /locus_tag="JAM15_09565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAT6798498.1"
                     /translation="MEVYALVGSSGTGKSFKALEFAYENDIEYIIDDGILIYKNKVLA
                     GISAKQANTTIEAVKRAIFYNLEHRQEVREAIKKENIRKILIIGTSKKMVNQIVERLS
                     IGRVYKFINIQDISTKYEIEIAKQARKEGNHVIPVPAVEIKSMASGLSINSLKRLFRK
                     GNNRNMVVLEKTIIRPTFSYIGKFYISADVIKQIIEYEVYNFGSIDRINKINIENCNN
                     FMNIFVSININDLETIKKIEDIQQTIKKSIEKMTLVNVQKIDINIHKIKKINFLQC"
     gene            6230..7495
                     /locus_tag="JAM15_09570"
     CDS             6230..7495
                     /locus_tag="JAM15_09570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012342769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-specific glutamate dehydrogenase"
                     /protein_id="HAT6798499.1"
                     /translation="MSGKDVNVFEMAQSQVKNACDKLGMEPAVYELLKEPMRVIEVSI
                     PVKMDDGSIKTFKGFRSQHNDAVGPTKGGIRFHQNVSRDEVKALSIWMTFKCSVTGIP
                     YGGGKGGIIVDPSTLSQGELERLSRGYIDGIYKLIGEKVDVPAPDVNTNGQIMSWMVD
                     EYNKLTGQSSIGVITGKPVEFGGSLGRTAATGFGVAVTAREAAAKLGIDMKKAKIAVQ
                     GIGNVGSYTVLNCEKLGGTVVAMAEWCKSEGSYAIYNENGLDGQAMLDYMKEHGNLLN
                     FPGAKRISLEEFWASDVDIVIPAALENSITKEVAESIKAKLVCEAANGPTTPEADEVF
                     AERGIVLTPDILTNAGGVTVSYFEWVQNLYGYYWSEEEVEQKEEIAMVKAFESIWKIK
                     EEYNVTMREAAYMHSIKKVAEAMKLRGWY"
     gene            7708..8298
                     /locus_tag="JAM15_09575"
     CDS             7708..8298
                     /locus_tag="JAM15_09575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HAT6798500.1"
                     /translation="MHFKSKDLNLKYLVLFLKIVYWFNPFIYIMEKYMDLDCELYCDE
                     RVLKNCTVQQKQEYALTIVNSMKRSTNFSNKFVAGLNKQSDIKKRVINMFSEKHKNGI
                     LRALIISLFSSITFLKFDSTSIIEENDFLERSRYTFEGRQEDMFVTIDFIYADAPIKL
                     RKEHEENCRVNGIVPKDSDSIEIIPRFYKDCMDLKK"
     gene            8628..9767
                     /locus_tag="JAM15_09580"
     CDS             8628..9767
                     /locus_tag="JAM15_09580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M56"
                     /protein_id="HAT6798501.1"
                     /translation="MSNFILNGIFRTVIVSSLSILMILIFKKNVFKRFSKKFNYYIWM
                     IVVIKLFLPFTYYTFTINILRSKKHININNINLEGFNNVSTISNNIILYTWIITVVVY
                     LIYTIFKYIKLKNLINDLSYDVDDREIVNLYKNILEEFNITKDIKLKYSYEVETPAFF
                     NSCVLLPPHEYKLKELDWIFRHELMHFKSRDLYLKYVILFLKTVYWFNPFIYIMDKHI
                     DLDCELYCDERVLKNRNSEEKKDYALTILNAMRKGSNTSNKFIAGLHKQSDIKKRVMN
                     MFNEKYKNGILMALTLCLLSSITFLKVNSTSIVNLNILPKYDMEKLHVFRGSVTLLEF
                     TYADAPENVKKEHKRMYEAMGLIPKDSDKISFGVKYYDKLNNLLR"
     gene            10238..11260
                     /locus_tag="JAM15_09585"
     CDS             10238..11260
                     /locus_tag="JAM15_09585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HAT6798502.1"
                     /translation="MKKKILIPVFASVMALSVSSIVNADEVNDSSQNKDDKTNTELNL
                     GEYKEVKYKVAKIKDGVAIKIREEGQVQNIAYSGDEFTVLGTQGEWVKVKVEDGEGWL
                     ATRYVDISEGVGYTNADKVNLRKDKSESSEVIEELEKGSSLLVLEDNGDWLKVKDGET
                     EGYVKSSYISDKAPVIEEPQVNPSIDQNVDSTNNNQQNNANTNQQNNNSNVPTANSNA
                     VQAVLNLAYSKQGCPYVWGAEGPNTFDCSGFTQYVYRNAVGKNIPRTSKAQSKYGQTV
                     SKANLQPGDLVFFTTNGSGSVSHVGIYVGGGNMIHSPSTGKTVSVTSINSSYYTARFV
                     TAKRIL"
     gene            11556..12476
                     /gene="pyrB"
                     /locus_tag="JAM15_09590"
     CDS             11556..12476
                     /gene="pyrB"
                     /locus_tag="JAM15_09590"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HAT6798503.1"
                     /translation="MLKSRNLIQPEDFSIEEIDEILELAQKIIDNPSKYSRICEGKLL
                     ATLFYEPSTRTRLSFESAMNRLGGRVVGFSEPNSSSASKGETLGDTMRIVSGYVDIIA
                     MRHPQSGAASEAARYTEVPFINAGDGKNQHPTQTLTDLLTIKSLKGTLESHTIGLCGD
                     LKYGRTVHSLVKAMARYKNTKFVFIAPEELKMPDYIKEAIKGHAYYETNNLDDVIGSL
                     DVLYMTRVQQERFEDKSEYERLKNYYILNKAKLEKASKDMLVMHPLPRVNEIDIDVDS
                     DDRAVYFKQAKYGMYVRMALIIKLLGINED"
     gene            12515..13207
                     /locus_tag="JAM15_09595"
     CDS             12515..13207
                     /locus_tag="JAM15_09595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HAT6798504.1"
                     /translation="MYKILENIYIGEDMYRMKVKGNFEGKMGQFYMLRAWDTYPVLSR
                     PISIHDIDEEGITFLYKVVGEGTQILSNLKVNDNIKLEGPYGNGYAKVDGKVALVGGG
                     IGVAPLYLVAKNIKNCDAYLGFREDVILEDEYKQVCNKVYTTVGNTFVTDIIDVEKYD
                     YILTCGPTPMMEKLVKMVEGTKTRIMVSLENHMACGVGACLVCTCKTNGGNKKTCKDG
                     PVFWGEDVIFNG"
     gene            13200..14102
                     /locus_tag="JAM15_09600"
     CDS             13200..14102
                     /locus_tag="JAM15_09600"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HAT6798505.1"
                     /translation="MGNLSVKFGSVEFKNPVIMASGTFGFGKEYNEIYDIQKLGGISS
                     KGLTLNKKPGNNGMRVHETPSGMMNSVGLENPGVQGFIDYELPFFSKLDLVRIANVGG
                     GTLEDYLLGVQMLNDKPIDIIELNISCPNVKAGGMAFGIKNEVAREVVREVRNITKLP
                     LVIKLSPNAEDIVGMAKVCEEEGADGVSLVNTFKAMAIDIKNRRPVFENVYAGLSGPA
                     IKPIALRMVHEVCKNVNIPVMGMGGITKATDAIEFIMAGATCIQVGTANFMNPRIGIE
                     IIDGINEFMDREGIKSLDEIRGII"
     gene            14187..14771
                     /locus_tag="JAM15_09605"
     CDS             14187..14771
                     /locus_tag="JAM15_09605"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HAT6798506.1"
                     /translation="MSKVDVVDILKKSDALLEGHFLLSSGKHSNRYVQCAKVLRFPEY
                     AAEVLSTVVEQIKDLDIDLVVGPAMGGVIVSYELGRQLGKEAVFTERKDNTMELRRGF
                     EVKKGAKIIIAEDVVTTGKSTMETKRVLEALGGEVVGVACIADRTNHDIGMPIYSAIK
                     LDIQVYESDECPLCKEGKLPVVKPGSREFKELGM"
     gene            14986..15912
                     /locus_tag="JAM15_09610"
     CDS             14986..15912
                     /locus_tag="JAM15_09610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketopantoate reductase family protein"
                     /protein_id="HAT6798507.1"
                     /translation="MKNQLNENHKKVVFFGVGAVGATFAEQFFNSKYDFKILCDNERK
                     KRYLEEGFIINGKRYDFNYVTKDEYKQEADFIIIGLKYNNLKENIKELDGLVGKNTVI
                     MSLLNGVDSEEIIGERFGIGKMVYSYVTNIDAKKINNNIIHTTNGIIVFGNKDNSEDR
                     KTNIITEVFDDVNIEYILSKDIQRDMWWKYMVNIGVNQTSAILGAPYGVFQSSEHLRE
                     LAKSAMREVVAIAQAKDISLTEDDVENSLHRILEHSKEGRTSMLQDVEAHRPTEVDMF
                     SKNICKLGKKYSIPTPINQTLFYMIKVIESRF"
     gene            complement(15964..16854)
                     /locus_tag="JAM15_09615"
     CDS             complement(15964..16854)
                     /locus_tag="JAM15_09615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAT6798508.1"
                     /translation="MFEELKTFVAVVEYKNFTKAGEYLNLSQPSVSKHIKNLENYFKV
                     VLINRSIKQKTIFITESGQILYKRAKEILNLLNITYHDVSQVSDAITGHLKIGASLTI
                     GEYILPNFLALFSQKYPDIDVEVFIKNTSIVSSHVKDYILDIGLIEGTCSSPSFIQEY
                     FFEDKMVLALPYNSHLLKDFSFDKLQDQKWIVREDGSGTRDYLDMFLSVKEIIPKSMM
                     VFGSNYAVKESVRNNLGITIVSNLVTSLPVLNNELSVIELGSSYNRHFSYIFPKDITL
                     SKAATIFIEELKIFSNLNSI"
     gene            17042..18073
                     /locus_tag="JAM15_09620"
     CDS             17042..18073
                     /locus_tag="JAM15_09620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HAT6798509.1"
                     /translation="MLKKKSSLTLKTIREILPGLFISVLVGYISIFISILIPKVGAAS
                     ISIFLGMFVGNLFLNQKVFQKGYKFSETDLLSYSIVLLGATLSVSTLIDLKVSGILFI
                     ILQMTITIIAALYIGKKLGFEENFRFLMASGNAVCGSSAIGATVPVVNATDKEKGIAV
                     TIVNVTGIFLMFLLPIISQFLYSHELVKTSAMIGGTLQSIGQVVASGAIVGENVKDLA
                     TIFKIVRVIFLVVVVLVFGHMKNQSNREILEEEKDEIKKKKVTIPWYVIGFFITCALF
                     SMNIIPKEVSVLCKEISNKLEIIALAAIGLKVNVKDLVKQGKEVSLYGLFVGTVQVVS
                     AVVLIKIFI"
     gene            18367..19242
                     /locus_tag="JAM15_09625"
     CDS             18367..19242
                     /locus_tag="JAM15_09625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxoguanine DNA glycosylase"
                     /protein_id="HAT6798510.1"
                     /translation="MNVYEKGNGVILEGVTDFDPVHIFECGQCFRWHKQEDGSYTGVA
                     RGRILNVKKENDKIYLNNTNLKEFNSIWYNYFDLGTDYTEIKNKLKNMDEYLNKATEF
                     GWGIRILRQDGWEMLISFIISSNNRIPMIQRAIENLSRKFGKYIGEYEGNEYYAFPTP
                     EELNKASQEEIRACQTGFRDKYIKSTTQAVIENNDEVSEYTNLSTEDCRKELLKFNGV
                     GPKVCDCIALFGMQKYDSFPVDVWVKRVMQEFYIDEDMSLPKMRTYGIDKFKEMSGFA
                     QQYLFYYARELGIGK"
     gene            19260..20750
                     /gene="cls"
                     /locus_tag="JAM15_09630"
     CDS             19260..20750
                     /gene="cls"
                     /locus_tag="JAM15_09630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HAT6798511.1"
                     /translation="MGVIGTIFLFYLIISYLAGAIISVIILLENRDPAKTMSWLLMFI
                     IFPGVGLMIYAISGRNIRKRKLFKTQKLANNIKEKKLFDTLEKITEIVELEKESIKQN
                     KLLRDEEDGSYRKRVINMLLKTGMFPFTKNNKVDVFVDGNEKFKRLIEDIREAKDHIH
                     LEYFIIKDSEIGRVLKEELIKKAKEGIKIRILYDDVGCWRFWFNRKFFREMREVGIEI
                     AAFLPTKFPIIGGKLNYRNHRKIVVIDGIIGYTGGINIGDEYLGKNDKFGYWRDTHIR
                     IKGISVYMLQMTFLIDWYYTTKEVLVTKNYFPSVGNVGESMIQVVASGPDSDWEDIHY
                     AYFSAICQARKNVYIETPYFIPDESLLKAIKSAALSGVDVRIIFPKIADHKIVNIASY
                     SYFEEILRAGGKVYLYNKGFIHSKVVIIDDKIASAGTANMDLRSFMLNFEVNAFIYDE
                     EVIRVMTDDFFEDLSHCEELNLEVFKNRNIIQKIKESVARLFSPIL"
     gene            20943..21227
                     /locus_tag="JAM15_09635"
     CDS             20943..21227
                     /locus_tag="JAM15_09635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013360508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HAT6798512.1"
                     /translation="MKIRPLADRVVIKKVEAEEKTASGIVLPGAAKEQPQIAEVVEVG
                     PGGIVEGKEIKMELTVGDKVIFQKYSGTEVKIEGQEYTILRQSDVLAVIE"
     gene            21260..22888
                     /gene="groL"
                     /locus_tag="JAM15_09640"
     CDS             21260..22888
                     /gene="groL"
                     /locus_tag="JAM15_09640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004167116.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HAT6798513.1"
                     /translation="MAKEIKFSEETRRALEAGVNKLADTVKVTLGPKGRNVILDKKFG
                     SPLITNDGVTIAKEIELEDRFENMGAQLVKEVATKTNDVAGDGTTTATVLAQAIIREG
                     LKNVTAGANPILLRKGIQKAVTVAVEELKNQSRIVETQEAISQVASISAGDEEVGKLI
                     AEAMEIVGKDGVITVEESQTMNTELDAVEGMQFDRGFVSAYMVTDVDKMEAVLNDPYI
                     LITDKKISNIQELLPVLEQIVQQGKKLLIIAEDVEGEALSTLVVNKLRGTFDVVAVKA
                     PGFGDRRKEMLQDIAILTGAQVISEELGYDLKEADLSMLGRASSVKVTKESTTIVDGS
                     GDKKAIEDRVTQIKHQVEQTTSDFDREKLMERLAKLAGGVAVVKVGAATEVELKERKL
                     RIEDALNATRAAVEEGIVAGGGTAFVSVIPAIGTLIESLEGEVKLGAQIVKKALEEPL
                     RQIAINAGLEGAVIVQNVVKSEAETGFDALNEKYVNMIEAGIVDPTKVSRSALQNAAS
                     IASTFLTTEAAVADLPEKEDAGMPGMGGGMPGMM"
     gene            23150..23890
                     /gene="larB"
                     /locus_tag="JAM15_09645"
     CDS             23150..23890
                     /gene="larB"
                     /locus_tag="JAM15_09645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarB"
                     /protein_id="HAT6798514.1"
                     /translation="MDLRKLLEEVKNENIDIDFALEKLKDLPYEDLGYANIDHHRELR
                     NGYPEVIYCEGKSDEHILGIIDKMNQKSSNILGTRCRKETFLKIKEIYNHAEYEEASK
                     ILKIQNHDIENIGKGKIVIATGGTSDIPVADEAYHTAKFLGNDVDRIYDVGVAGIHRL
                     LNKRHKIDSARVIVAVAGMEGALASVIGGLVDVPVIAVPTSVGYGANFGGLAALLAML
                     NSCASGISVVNIDNGFGAGYLASMINKL"
     gene            23974..24708
                     /gene="larC"
                     /locus_tag="JAM15_09650"
     CDS             23974..24708
                     /gene="larC"
                     /locus_tag="JAM15_09650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarC"
                     /protein_id="HAT6798515.1"
                     /translation="MSEKILYFDIISGISGDMTLASLLNLGVPKEIFLEEIHKLRMSD
                     EFNINISSKTENGIVGTKVEVITKEKHTHRNLVDIFEVIDKSTLNENVKSKAKKIFMV
                     IGEAEAKVHGTTIDKIHFHEVGAIDSIVDIVGASILVDLLCVDKVCASTVSVGSGFVK
                     CEHGIIPIPAPATIEILKGVPIKLNNVNGECTTPTGAAIIKVLCDEFVDELEFSPKQI
                     GYGIGHKKFEVPNILRTVLGEKKKKN"
     gene            24738..25157
                     /locus_tag="JAM15_09655"
     CDS             24738..25157
                     /locus_tag="JAM15_09655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LarC family nickel insertion protein"
                     /protein_id="HAT6798516.1"
                     /translation="MSSEIYSYLYEKILDEKALDIYTESIYMKKNRPATKVSILCNES
                     DLEKFIKILLLETSTFGVRYNAYNREILERKFVKLDTKYGVVTVKLGYYKGKLVKVTP
                     EYNECKTIAKNEDIPIKKVFADINFRIKEEFSENLLT"
     regulatory      25217..25318
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            25539..27074
                     /gene="guaA"
                     /locus_tag="JAM15_09660"
     CDS             25539..27074
                     /gene="guaA"
                     /locus_tag="JAM15_09660"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007789015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HAT6798517.1"
                     /translation="MKHELVLVIDFGGQYNQLIARRVRENNVYCEILPCTASIERIKE
                     KNPKGIIFTGGPNSAYLEDSPTISKEIFELGVPILGICYGIQIMSHVLGGVVRKGNKQ
                     EKEYGKTSITYGKSSLFEGITTNSVWMSHTDLIEKVPEGFTIVANTNDCPVAAMENVE
                     RNLYGVQFHPEVEHCLEGDKILTNFLYNICKVKGDWTTDSFIEDKIKELKEKIGDKKA
                     LCALSGGVDSSVAAVLIHKAIGDNLTCIFVDHGLLRKNEGNDVERIFREKFDINLIRV
                     NAEDRFLSKLKGVSEPEAKRKIIGEEFIRVFEEESNKLGKMDFLVQGTIYPDVIESGH
                     GNAATIKSHHNVGGIPEDVDFQEIVEPLRELFKDEVRKIGLELGIEEGLIFRHPFPGP
                     GLGIRVIGDVTKEKCDILREADAVYMDELRKAGLYREIWQAFATLPDVKTVGVMGDER
                     TYAYLVGLRAVTSSDGMTSDWYKMPYDVLERISNRIINEVDGVNRVVYDITSKPPGTI
                     EWE"
     gene            complement(27151..28197)
                     /locus_tag="JAM15_09665"
     CDS             complement(27151..28197)
                     /locus_tag="JAM15_09665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAT6798518.1"
                     /translation="MPAYKDERRKSWYASFYFTDFNGDRKKKIKRGFKTKKEALEFER
                     EFLNKSKMSTDMSFESLIEEYMHDMSSRLKLSTLETKKYLINFRILPFFKSLKINEIT
                     ATHIRKWQNELLKSDYSQTYIKTINNQLVAVLNYAVKYYNLPSNPAHLAGTIGKKNAD
                     EMNFWTLEEFKKFIEFEKKPEPKLAFEILFWTGLRLGELLALTPKDIFENKISVEKSY
                     IKLNGEDIVSSPKTSKSKRVVPIPCFLYNNIKDYLSKLYDLKDNERIFKFAKSYLSKE
                     LNRCCKLSNVKRIRVHDLRHSHASLLVNMDVNILTIAERLGHEKVETTWNTYSHLYPN
                     KQLEVAQKLDNLNI"
     gene            complement(28273..28488)
                     /locus_tag="JAM15_09670"
     CDS             complement(28273..28488)
                     /locus_tag="JAM15_09670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6798519.1"
                     /translation="MLKKLRKKKRMTQLELAEKMGRNRSYISKLENQEYKDIGISTIL
                     DLSIALEEDFLELCKYYKFQEIKRRGK"
     gene            29142..29279
                     /locus_tag="JAM15_09675"
     CDS             29142..29279
                     /locus_tag="JAM15_09675"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798520.1"
                     /translation="MGDSDCSKMLAFYEIMKMLETIDETKFYNCKEEIKSEFKHIKKE
                     D"
     gene            complement(29306..29698)
                     /locus_tag="JAM15_09680"
     CDS             complement(29306..29698)
                     /locus_tag="JAM15_09680"
                     /inference="COORDINATES: protein motif:HMM:NF024252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6798521.1"
                     /translation="MYKDESNIFSKRLREEREELGLMQKEMANKLSLPANTYNGYETG
                     KRSPALDVVRHIADTLDISTDYLLGRTNIKINISNITEKELIKKLNPSDDMKEILDIF
                     SELDDDSKNKALKIAKLFLEEQNTKNKE"
     gene            29886..30080
                     /locus_tag="JAM15_09685"
     CDS             29886..30080
                     /locus_tag="JAM15_09685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008422227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6798522.1"
                     /translation="MKNYILKSLRVRQGLRQRDLAKILGMNPSTYSSKENGDRRFTVS
                     EAIKISDFFNTDLRDIFLNK"
     gene            30116..30907
                     /locus_tag="JAM15_09690"
     CDS             30116..30907
                     /locus_tag="JAM15_09690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6N domain-containing protein"
                     /protein_id="HAT6798523.1"
                     /translation="MNNLQVIEKNNERVLTTQQLADVYETDARNISNNFNNNKDRFIE
                     GKHYFLLQGDDLKHFKGIHTEYENLKFTSKMYLWTERGANRHCKILDTDKAWEQFDNL
                     EETYFKVKQHKPSCIEDVLIESLKEMKDLRLQVNRANNIALEAKAEVETIKDVVSLDS
                     NSWRTDTHQLIARIAKKQGGFEHINMLRTESYELLNKRFGVDLHRRLINKRRKMAEEG
                     VSESKREKVNNLDVIQDDKKLIEGYVAIVKDMALKYGISSDLSKN"
     gene            complement(31100..31279)
                     /locus_tag="JAM15_09695"
     CDS             complement(31100..31279)
                     /locus_tag="JAM15_09695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Arc family DNA-binding protein"
                     /protein_id="HAT6798524.1"
                     /translation="MSSTLPKYTLRINKILLEKIKYIAESEGRSANKEIEQLIKKHVE
                     NYEQIKGEIKVNIEE"
     gene            31356..31493
                     /locus_tag="JAM15_09700"
     CDS             31356..31493
                     /locus_tag="JAM15_09700"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798525.1"
                     /translation="MKHEQTTLRIPNDLYKALTDLSNEIGTPITSIIIIACWLYISKI
                     N"
     gene            complement(31479..31790)
                     /locus_tag="JAM15_09705"
     CDS             complement(31479..31790)
                     /locus_tag="JAM15_09705"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798526.1"
                     /translation="MTTITVRIYTPLNENLEKISCETGILKSSLILYAINDIIRNSKV
                     NELKSVSYKSEDSVRSTLRIPVVLKELLEKTAKENNLSINSLINNAVHSFCISDWLIY
                     L"
     gene            31910..32080
                     /locus_tag="JAM15_09710"
     CDS             31910..32080
                     /locus_tag="JAM15_09710"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798527.1"
                     /translation="MEKVRMTVRLVPKLNQYVQNIAKECGKSKNSIIVDACWEFIEKI
                     KKENKFNVESEE"
     gene            32083..32721
                     /locus_tag="JAM15_09715"
     CDS             32083..32721
                     /locus_tag="JAM15_09715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798528.1"
                     /translation="MNNLQIFEKLEFGQIRMAEIDNKPYFVGKDIAKSLGYKNTNDAI
                     LRHCKGVVKHEGFKINGIKVALITEGDVYRLIVGSNLPNAEKFESWVFDEVLPSIRET
                     GKYQLQQDVITELTGTIGDLKGTIREYKKMCKITCSKKQQYSRYIKNRLDIDKANKEY
                     NQVKARLFLILGVEKWEDIDFDTSNNLIQIIDDCIRVIKSERPYKQLSYFEN"
     gene            complement(32807..33166)
                     /locus_tag="JAM15_09720"
     CDS             complement(32807..33166)
                     /locus_tag="JAM15_09720"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798529.1"
                     /translation="MSNQNILDFLTLENKLSDKEIISLLGWKNRGKVTDIRRGKSNFT
                     IDDVLIISEKFHISVDYILKGKEYSADILKISKPTDNEQEILSLLHKFDERNQIKFIS
                     KVEDLADKMLEKGNDTE"
     gene            33336..33527
                     /locus_tag="JAM15_09725"
     CDS             33336..33527
                     /locus_tag="JAM15_09725"
                     /inference="COORDINATES: protein motif:HMM:NF024835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAT6798530.1"
                     /translation="MNKKCLPKWSKEVKKAMIDRDLKLDDLSEELGLSKYHLSAVIND
                     RLKSPNAKEAICKYLKVKG"
     gene            33560..34018
                     /locus_tag="JAM15_09730"
     CDS             33560..34018
                     /locus_tag="JAM15_09730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAT6798531.1"
                     /translation="MSYEYQNIYQKGRENTNLTQEKASELLDISVESLRAYENDKRIP
                     NNQIVAKMVSIYNNNLLGYEHVRRTTEAGVMFLPKLEMKSLSSITLKLHKEIKDYLKK
                     EDDFIDIVEDDVIDAEEEEVWNDVMEKLEGIYEAILKLKLSRNTKISKEV"
     gene            34021..34842
                     /locus_tag="JAM15_09735"
     CDS             34021..34842
                     /locus_tag="JAM15_09735"
                     /inference="COORDINATES: protein motif:HMM:NF015340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HAT6798532.1"
                     /translation="MKDLTIVKVNNKLTTDSRDIALMVEKEHKILLRDIRNYINQMEE
                     ANKNMSTDLYPSDYFIENTYLDDYKREKPCYAITKIGCDFIANKMTGIKGTAFTGTYT
                     KKFEEMEQELKQQLKCSYMIDDPIERAKRWIEEQEENQSLIKKKDNIIQLQQPKVEKW
                     ERFLNNEGLTTIEDFSKTLAIKGYGRNNMYKLLREMEYLKKDNSPYTKYVEQGLFTRK
                     PSGTHIEYGKVIEDYKTFLTSKGIDKIMEKLLKLGVIKQSSNVSYVEQKQLSILS"
     gene            34929..35120
                     /locus_tag="JAM15_09740"
                     /pseudo
     CDS             34929..35120
                     /locus_tag="JAM15_09740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056356.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            35124..35321
                     /locus_tag="JAM15_09745"
     CDS             35124..35321
                     /locus_tag="JAM15_09745"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798533.1"
                     /translation="MKISFESVVNNVNNETELILSKEELQIAKRILNILNENEQSILS
                     SKDILDFCKEALKYNLVPTFV"
     gene            complement(35308..35508)
                     /locus_tag="JAM15_09750"
     CDS             complement(35308..35508)
                     /locus_tag="JAM15_09750"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798534.1"
                     /translation="MKVGDIMQFSKDILHTLTLEILKKKYDFKNSSEEELLKHYHEIF
                     LKLSEVNNSFSKGDGLSVFKQT"
     gene            35561..35758
                     /locus_tag="JAM15_09755"
     CDS             35561..35758
                     /locus_tag="JAM15_09755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6798535.1"
                     /translation="MAINDNINKILRDRNIKAWKLAKEIGVDSGNLYSILRGKNKNPT
                     IDTLIKLADYLDVTLDELVGR"
     gene            35797..36006
                     /locus_tag="JAM15_09760"
     CDS             35797..36006
                     /locus_tag="JAM15_09760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798536.1"
                     /translation="MTKVVAKEQLFYRAKDVAKFLDICEATAYKIIAELNEELEKEGF
                     KTFSGRVSIAYFKERYCYKPRKGVI"
     gene            36105..36323
                     /locus_tag="JAM15_09765"
     CDS             36105..36323
                     /locus_tag="JAM15_09765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798537.1"
                     /translation="MVMVFNLDKLKVGNAIRISCERFGFEIDCIVVVATEEELNLAYY
                     SKDKGCIEYQALIPEDIRYGDYILERLA"
BASE COUNT        14449 a         3869 c         6438 g        11591 t
ORIGIN      
        1 ggtaaatcgt ggtattaaat aagtagattt taatagttaa attatagtca attataataa
       61 agctatttaa tctacttttt taatataaaa atataagggg gaatttgtaa tggcttgtaa
      121 cacttgtaaa atgtgcgaaa gtgcagacaa gaaattagaa agttttgtag cttcaaagga
      181 tgttgaaaca gcatttcata gaacagaaga tcagaaagtt aagtgtggtt ttggacttca
      241 gggggtttgt tgtagactct gttcaaatgg accatgtaga gtaactccta aatcaccaag
      301 aggtatatgt ggagcagatg cagacactat agtagcaaga aactttttaa gagcagtagc
      361 atcaggagca gcttgttatt tacatgtggt agaaaataca gctaagaatt taaaaaatgt
      421 tggaataact aaaggtgttg ttaaaggaga aaaaacatta aatcaattag cagagatgtt
      481 tggaatagaa agtgatgaaa agtatgataa atgtataaag gttgcagaca aagttatcaa
      541 cgatttgtat aaatcaagag atgataaaat ggaattagta gaaaaaatag cttatgcacc
      601 tagagtgaaa aagtggaaag agttaggtat aatgcctggt ggtgcaaagt cagaagtttt
      661 tgatgcaata gtaaaatcat caacaaattt aaatagtgac ccagtagaca tgctagttaa
      721 ttgtttgaac ttaggtatat caacaggatt atatggtctt acactaacta atcttttaaa
      781 tgatgttatg ttgggagaac cagttataag aatggctcct gtaggattta atgtaataga
      841 cccagactac ataaatataa tgataacagg ccatcaacat tcaacatttg caaatttcca
      901 agatagatta aaagatgaag atgttataaa attagctcaa tctgttggtg caaaaggctt
      961 taagctagta ggatgtacat gtgttggtca agatttacaa ttaagaggag aacattatca
     1021 agaagtattt gctggacatg caggtaacaa ttttacaagt gaagctgttt tatcaactgg
     1081 agcaatagat atagttcttt cagaatttaa ctgtactata ccagggcttg aaccaatagc
     1141 agataaatat aaagtaaaaa tggtttgttt agatgatgtt gctaaaaaag cgaatgcaga
     1201 atacataggt ttagacagaa gtaaattaga tgaacttagt aacactttaa tagaaaaagc
     1261 attggagtct tataaggaga gaagaggaag tattgaaata gatataccaa aagaccatgg
     1321 atttgaacaa tctttaactg gtgtaagtga aaagaacctg aaagcgtttt taggagattc
     1381 atggaaacct cttattaatt taattgcaga aggaaaaatt aaaggtgttg cagctgttgt
     1441 aggatgttca aatatgacag caggaggaca tgatgtaaat actgttgaac ttactaaaga
     1501 attgattaaa aaagatataa tagtactatc tgcaggatgt tctactggag gattagaaaa
     1561 tgttggtctt atgtcacctg gagcagaaga attagcagga gaaaacttaa aagaagtatg
     1621 taagacttta ggaataccac cagtattaaa ctttggacca tgtctagcta taggaagact
     1681 agaaatagta gcaacagaat tagcagctga acttggaatt gacctaccac aattaccatt
     1741 agtgctttca gctccacaat ggttggaaga acaagcatta gctgatggag cgtttggtct
     1801 tgcccttggc ttacctcttc atttagcttt acctccattt ataacaggag gaaaattggt
     1861 gacagaagta ttaacagaaa aattaaaaga cttaacagga ggacatgtta tagtgaatcc
     1921 agaccctaaa tcttcagcta atcaattaga agaaataata atagatagaa gaaaaaattt
     1981 agggttaaag gatgtggaat gcaatgcata gaatttttat aaataaagat ttatgtacag
     2041 gatgtaagag ctgtgtacta gcatgtatgc taaaacacaa taaagattat gacatgtaca
     2101 ctcttgattt agaaaatata gataatgata gtagagggca tatagaatta gatagtaaac
     2161 ataataatcc agttccaatt ctttgtagac actgtgatga acctgaatgt gtattagcat
     2221 gtatgagtgg tgcaatgcat aaagatagtg aaagtggaat cgtttcatat gatgaagaga
     2281 aatgtggttc atgttatatg tgtgtaatgt cttgtccata tggattatta aagccagatg
     2341 atagaagcaa gcagaacata cttaaatgtg atttatgtaa agatgaggag tatcctagat
     2401 gtgtagctaa ttgcccaagt ggagcaattg aattacagaa ggaggaaaat gatgaattat
     2461 gtagtgttag gggctagtgc agctggtata aatgcagtaa aaacattaag agaattagat
     2521 aaagattcaa atatagtagt aatttctaaa gatgaaaacg tatattcaag atgtatgttg
     2581 catcatgtta tatctgaaca cagaacttta aaacaaataa attttgttga tgaagatttt
     2641 atggagcaaa ataatgtaaa atggattgca ggtaagactg ttaaaggtat agacataaat
     2701 aaaaaggtag ttcagacaga agacattact gtaaattatg ataaactttt aatagctaca
     2761 ggtgcatctt ctgctattcc tcctataaaa aatttaagag atggaaattt tgtatattct
     2821 gtgagaaaca tagatgatat ttataaaata aaagaaaaag cacaaaattc taaaaatgta
     2881 gttataatag gtgctggttt agttggtata gatgcattag tgggattatt taaatatgag
     2941 cagttaaata tttctgtagc ttttatggaa aagtacattt tagacagaca attggatgaa
     3001 tatacagcat cagtgtatga aaataagttc aaagaaaaag gtgtaaaatt ttacccaagt
     3061 gcatcaatac aagaaattgt attggataac agtaagaatg ttacaggtgt tgcattttca
     3121 aatggtgaag ttttagatgc agacatggta attgtagcta caggggttaa accaaatgct
     3181 gactttttag atggaacagg aatagaatat gatagaggta taataataga tgatatgtgc
     3241 caaacaacac aaaaagacat atatgcagca ggagatgttg taggtaaaaa tgctatttgg
     3301 cctctggcag taaagcaagg aattgtagct gcctataata tggttggaaa agataagaag
     3361 atagaagatg aatttgcttt taaaaatagt atgaatttca tggatatatc aactatttct
     3421 ataggaatga atacacctgt agatcatagc tataaagtat taaccagaca tggaattaat
     3481 gattataaaa agtttgtttt taaagataat gtaatatatg gagcagttat acaaggagat
     3541 atttcatatg taggtgtatt aacttattta ataaaaaata aagttgaaat atatgattta
     3601 gaaaatagga tatttgatgt atgttatgca gactttttta atataaaaga aaatggagaa
     3661 ttttgttata gtgtatagta tatacgtgga gtaaggttta taaatacagt aaatcaataa
     3721 atagagttat tctaaaataa gaaaaatgac aaatcttatt tagaaatagc tctatttttt
     3781 gtaattaaat ttaaattata ttcaatttgt aaaatattat tttgaacaat tatacatata
     3841 ctctctagtt agaggtaaat cattttttat acctttagtg aaaagtattt gatgtatatc
     3901 tataatacca gtgttgaaag cagcagcaca agaacaaagg tataaatccc acattcttat
     3961 aaacttatca tcaaacattt ctttaatctt tggaagattc tcagagaaac ttttttgcca
     4021 gtatagtaag gtttttacat aatgtaatct taaactttct acgtctatag tatgatattt
     4081 gtaatcacta caaatatgta tcatttctct taggctagga ataactcctc ctgggaaaat
     4141 atattttttt atccaagggt ctccataaga ttcctgcaat ccacttatat agtgaagtaa
     4201 aaacaatcca ccatctttta aaacagcatt tacgttttta atgaaaagtt catagttttc
     4261 tctaccaaca tgttcaagca tcccaacgct tacaactcta tcaaacataa ggtctgattt
     4321 ttttaattct ctatagtcca taagtcttac ctcaaggtag tcttgaaggt tctcttcttt
     4381 aattcttgcg ttaaattcct taaattgctc ttcgctaagt gtaattccaa cgccgtgaat
     4441 tttatatttt tttgcagctt ctattagtaa aaatccccaa ccacaaccaa tatcgagaag
     4501 gctcatacct tcctctaaat ttagtttagt taatatgtgg tgaactttat tgacttgagc
     4561 atcataaaga gtatcattat catttctaaa gtatgcacaa gaataactaa gtgtcttatc
     4621 taaccataag ctataaaaat cgttgccaat gtcatagtgg gcatgtattt ctttcttttg
     4681 atgtctcatt gaatttgatg agtgcaatag atgttttaca gctgaattat caatattgaa
     4741 tttgtctatt tgttttaaaa gtagatttaa agttaagaat aaatctccct caacttcaat
     4801 gtctctattt atgtaggctt ctccaagtgc taaagatgta ctttttaata gttcagactt
     4861 gctaatatca ttatttacta taactttgaa ctgaggggaa ccctctccaa ttagaaattc
     4921 ttcctcgtct ttaagcctaa ctagaaatgg tgtttcacca aatttctcta aatagtcttt
     4981 taaaaaattt tttgtaatat tcatattacc agctccttct aatgtaaatc cagtaagttt
     5041 ccctgcttaa aatatattat agtccttttt ttaaaaaagt aaaatttttt caataaattt
     5101 tttatttaaa ggaaatttat tttttataaa gaaatttcat gttgtagtat attttttgct
     5161 tataaatttt ggtactggat ataatattaa actgttaatg atataataaa tttaatctat
     5221 aaagtaaata aaattttgta ataaatagtt aaagctattt tataaggaga tatatgatgg
     5281 aagtatatgc tttggttggg tcaagtggca cagggaagag ctttaaggct ttagagttcg
     5341 catatgaaaa tgatatagaa tatataattg atgatgggat tttaatatac aaaaacaagg
     5401 ttttagctgg gatatcagca aaacaagcaa atactactat agaagcagtt aaaagggcta
     5461 ttttttataa tttggagcat agacaagaag ttagagaagc aattaaaaaa gaaaatataa
     5521 gaaaaattct tattattggg acatcaaaaa aaatggttaa tcaaattgta gagagattgt
     5581 caattggaag ggtctataag tttataaata tacaagatat aagtactaaa tatgaaatag
     5641 aaatagcaaa acaagctaga aaagaaggaa atcatgtaat tcctgttcca gcagttgaga
     5701 taaaaagtat ggcaagtggt cttagtataa attctttgaa gagacttttt agaaaaggaa
     5761 ataataggaa tatggtagtt ttagaaaaaa caattataag accaactttt agttatatag
     5821 gaaagtttta tattagtgct gatgtaatta aacagattat tgaatatgaa gtatacaact
     5881 ttggaagcat tgatagaata aataaaatca atatagagaa ttgcaataat tttatgaata
     5941 tttttgtaag tataaatatc aatgatttag aaactataaa aaaaattgaa gacatacaac
     6001 agacaataaa aaagtctatt gagaaaatga ctttagttaa tgtacaaaaa atagatatta
     6061 acattcataa aattaaaaaa ataaacttcc tccaatgtta aaaaataaac tgagaaaatg
     6121 atatactaat ttgcaataaa gtgtgctata attaaactgt aaatttagga aatggttttt
     6181 tctaaatgga gtatacataa ttataacgta tttataaggg ggctttcaaa tgtcaggaaa
     6241 agatgtaaat gtcttcgaga tggcgcaatc tcaagtaaaa aatgcatgtg ataaattagg
     6301 tatggaacca gcagtttatg aattattaaa agaacctatg agagttatag aggtttcaat
     6361 tccagtaaaa atggatgatg gttctataaa aacttttaaa ggatttagat cacaacataa
     6421 tgatgcagta gggccaacaa aaggtggaat aagattccat caaaatgttt caagagacga
     6481 agtaaaagct ttatctatat ggatgacttt caagtgttct gtaacaggta taccatatgg
     6541 tggaggtaaa ggtggaataa tagtagatcc atcaacttta tctcaaggtg aattagaaag
     6601 attaagtaga ggatacatag atggaatata taaattaata ggtgagaaag ttgacgttcc
     6661 tgcaccagac gtaaatacta atggtcaaat aatgtcttgg atggttgatg agtacaataa
     6721 attaactgga caaagttcta taggtgttat aactggtaag ccagttgaat ttggtggttc
     6781 tttaggaaga acagctgcta ctggatttgg tgttgctgtt actgcaagag aagctgctgc
     6841 taaattagga atagatatga aaaaagctaa aatagctgtt caaggtatag gaaacgttgg
     6901 ttcttataca gttcttaact gtgaaaaact tggtggtact gttgtagcta tggctgaatg
     6961 gtgtaaatca gaaggttctt atgctatata caatgaaaat ggtttagatg gtcaagctat
     7021 gttagattat atgaaagaac atggtaactt attaaacttc ccaggagcta agagaatatc
     7081 tttagaagag ttctgggctt cagatgttga tatagtaata ccagctgcat tagaaaactc
     7141 tataactaaa gaagttgctg aatctataaa agctaaatta gtttgtgagg ctgctaatgg
     7201 accaactact ccagaggctg atgaagtatt tgctgaaaga ggaatagttc ttactccaga
     7261 tatattaact aatgctggtg gagttacagt ttcttacttc gagtgggtac aaaacttata
     7321 tggatactac tggtcagaag aagaagtaga gcaaaaagaa gaaatagcta tggttaaagc
     7381 atttgaatct atttggaaaa tcaaagaaga gtacaatgtt acaatgagag aagctgctta
     7441 catgcattca attaagaaag ttgctgaagc tatgaaatta agaggatggt actaagattt
     7501 actcttaata aataatagga tataattatt taagatataa aggggctgta catagtacag
     7561 cccttaaatt atgtggctta caatgaagta agctattttt gttttaactt ataaataact
     7621 tgataaatta tgtaatttag aatgtatttt ttaccaccac atgattacaa attagaagag
     7681 ttagattgaa tttttagaca tgaacttatg cattttaaaa gcaaagacct taatttaaag
     7741 tatctagtat tatttttaaa aatagtatat tggtttaatc catttatata tataatggaa
     7801 aaatatatgg atttggattg tgaactttat tgtgatgaga gagttttaaa aaattgtact
     7861 gtacaacaaa agcaagaata tgctctaact attgtaaatt caatgaaaag aagtacaaat
     7921 ttttcaaata aatttgtagc tggattaaat aaacaatctg atattaaaaa aagagtaata
     7981 aacatgttca gtgaaaaaca taaaaatggt atcttaaggg ctttgattat aagcttgttt
     8041 tcttctatta catttttaaa attcgattca actagtatta ttgaagagaa tgatttctta
     8101 gagaggtcaa gatatacgtt tgaaggaagg caagaagaca tgtttgtaac aatagatttt
     8161 atatatgcag atgcacctat aaaacttaga aaagagcatg aagaaaactg tagagtcaat
     8221 ggaatagtac caaaagattc agattcaata gaaattattc ctagatttta taaagattgt
     8281 atggatttaa aaaaataagt tagacttaat attgatgttg atattatgaa ttttttatat
     8341 ttaagcaatt gaaaatttta ttatagattc aattttatat gtgtttaagt atgaaattta
     8401 tagatagttg aaataattaa atatgattga tgcataggaa tcattactaa gctataatta
     8461 attatagggg agtttaaata aattatgagt tacacaatta taaaatgata aaaatagtta
     8521 tctgttacaa aaaatgtatc tttttaatta ataaagataa tatgaaaact taaaaggcaa
     8581 ataaacttaa acataaaata ctcttaaata agataggaga aaaatgtatg tctaacttta
     8641 ttctaaatgg gatttttaga acagttatag taagtagtct aagcattctt atgatattga
     8701 ttttcaagaa aaatgtattt aaaagattta gcaaaaaatt taattattat atatggatga
     8761 tagttgttat taaattattt ttaccattta catattatac ttttacaata aatatcttga
     8821 gaagtaaaaa acacattaat attaataaca taaatttaga gggatttaat aatgtttcaa
     8881 ctataagtaa taatattata ttgtacactt ggattataac tgtagtagtt tatttaattt
     8941 acactatatt taaatatata aaacttaaaa atttaataaa tgacttatct tatgatgttg
     9001 atgatagaga gattgtaaat ctttataaaa atatattaga agaatttaat ataacaaaag
     9061 atataaaact caaatactct tatgaagttg aaacaccagc attttttaat tcatgtgtac
     9121 ttttgccacc acatgagtat aaattgaaag agttagactg gatttttaga catgagctta
     9181 tgcattttaa gagtagggac ctttatttaa aatatgtaat cctgttttta aaaacagtat
     9241 attggtttaa tccatttata tatataatgg ataaacatat agatttagat tgtgaacttt
     9301 attgtgatga aagagtttta aaaaatcgaa attcagagga aaaaaaggat tatgctttaa
     9361 caattctaaa tgcaatgaga aaaggttcaa atacttcaaa taaatttata gctggacttc
     9421 ataagcaatc tgatattaaa aagagagtta tgaatatgtt taatgaaaag tacaagaatg
     9481 gtatattaat ggcattaact ttatgtttat tatcttctat tacttttttg aaggttaatt
     9541 caacgagtat tgttaatctt aatatattgc ctaaatatga tatggagaag ctacatgttt
     9601 ttagaggaag tgttacactt ttagaattta catatgcaga tgctcctgaa aatgttaaaa
     9661 aagaacataa aagaatgtat gaagcaatgg gattgattcc taaagactct gataaaataa
     9721 gctttggtgt aaaatactat gacaagttga acaatttatt aagatagata tttatataat
     9781 agcaaatagc tgaaacttaa aagaatttaa aagtaagtat tcacaaaagt cctaaagaaa
     9841 gtattaataa ttatattcaa ttgtaaaaaa tttcacaaaa caaccaactt ttatagttat
     9901 ttcatcaaaa aatatacgcc atataaaagc gcataaaaaa acacataaaa caatatttat
     9961 gcgcacttta acctcgaatg gtacaaaatt ctttactttt acagacccat attatataat
    10021 taagtaaata atgtatattt aggtgacata ttggataagc taatttattt attttattaa
    10081 tataatgata ctataaaagt tatataaagt ggtttacaaa aaagttacag atagagcttt
    10141 tattaatgta ttgtgtatta gtattttatc cttaggtaca cttcacctac aaaatagaat
    10201 cataagataa ttatgggaaa attttaggag gtttatcgtg aagaaaaaga tattaatacc
    10261 agtatttgca tcagttatgg cattatcagt aagttcaatt gtaaatgcag atgaagtaaa
    10321 tgattcatct caaaataagg atgataaaac aaatactgaa ttaaatttag gtgaatataa
    10381 agaagtaaaa tataaagttg caaaaataaa agatggagta gctataaaga taagagaaga
    10441 aggtcaagtt caaaacatag cttattctgg agatgaattt acggttttag gaactcaagg
    10501 agaatgggtt aaggttaaag ttgaagatgg cgaaggttgg ttagctacta gatatgtaga
    10561 tatatctgaa ggtgtaggat atactaacgc tgataaagta aacttaagaa aagataagag
    10621 tgaaagttca gaagtaattg aagagctgga aaaaggaagt tctttattgg ttttggaaga
    10681 taatggagat tggttaaaag ttaaagatgg ggaaacagaa ggatatgtaa aatcatctta
    10741 tatatctgat aaagctcctg taatagaaga gccacaagta aacccaagta ttgaccaaaa
    10801 tgtagattct acaaataata atcaacaaaa caatgcaaat actaatcaac aaaataataa
    10861 ttcaaatgtg ccaacagcta actctaatgc agttcaagct gtacttaact tggcatattc
    10921 taagcaaggt tgtccatatg tttggggagc agaaggacca aacacttttg actgttctgg
    10981 atttacacaa tatgtgtata gaaatgcagt aggaaagaat ataccaagaa catctaaagc
    11041 acaatctaaa tatggacaaa ctgtaagtaa agcaaattta caaccaggag atttagtatt
    11101 cttcacaact aatggttctg gttctgttag tcatgttgga atatatgtag gtgggggtaa
    11161 tatgatacat tcaccatcaa caggaaaaac agttagtgta actagtataa attcatcata
    11221 ctatacagca agatttgtta cagcaaaaag aatattataa tcggtttgta atatgacaaa
    11281 ttgataaata cataaatata tataaacgct ctatattata tttaatttaa tcatggaaac
    11341 aaaaaatgat tatattttaa atgtactata gagcgttttt gtatcacttt aaatctaatc
    11401 aagattcaag ttaatatgac tgttaaatag gagccttttc atatgatgat tatttgcgca
    11461 atcccttgac aggatagggc aaaggtggta agctactaac agtacaaaaa tacttttaat
    11521 tttagttcag agaggctaaa aaaggaggac gaaagatgtt aaaatcaaga aatttaatcc
    11581 aaccagaaga cttttcaata gaagaaatag atgaaatatt agaattagct caaaaaataa
    11641 ttgacaatcc gtcaaaatat tctcgtatat gtgaaggaaa actattagct acattatttt
    11701 atgaaccatc aacaagaaca agattaagct ttgaatctgc tatgaacaga ttaggaggac
    11761 gtgtagtagg cttttcagag ccaaattcat cctctgcatc aaaaggtgaa actctaggag
    11821 atacaatgag gatagtatct ggttatgttg atataatagc tatgagacat cctcaatcag
    11881 gtgcagcttc agaagcagct agatatacgg aagtgccatt tataaatgca ggagacggca
    11941 aaaaccagca tccaactcaa acacttacag acttacttac tataaaatca ttaaaaggaa
    12001 ctttagaaag ccatacaata ggattatgtg gtgatttaaa atatggaaga actgtgcatt
    12061 ctttggttaa ggctatggca agatataaaa atacaaagtt tgtatttata gcgcctgaag
    12121 agttaaaaat gccagattat ataaaagaag ctataaaggg acatgcatat tatgaaacta
    12181 ataatttgga tgatgttata ggaagcttgg atgttttata tatgactaga gttcaacaag
    12241 aaagatttga agataaatca gagtatgaaa gacttaaaaa ctattatatt ttaaataaag
    12301 ctaaattaga aaaggcatct aaagatatgt tagtaatgca tccattacca agagtaaatg
    12361 aaatagacat agatgtagat agtgatgata gagctgtata ttttaaacaa gctaaatatg
    12421 gaatgtatgt tagaatggct ttaataataa aacttttagg tataaatgaa gactaatagt
    12481 tatcatataa tagtaaaaca aaggagattt tgggatgtat aaaattctgg aaaatatata
    12541 tataggcgaa gatatgtata gaatgaaagt aaaaggtaat tttgaaggta aaatgggaca
    12601 attctatatg ttaagagcat gggatactta tccagtactt tcaagaccta taagtataca
    12661 tgatatagat gaagaaggga taacttttct ttataaagta gtaggagaag gaactcaaat
    12721 tttgagtaac ctaaaggtaa atgataatat aaaattagaa ggcccttatg gtaatggata
    12781 tgctaaggtt gatggaaagg tagctctagt aggaggagga atcggtgtag ctccactata
    12841 tttggttgct aaaaatataa aaaattgtga tgcatatctt gggtttagag aagatgttat
    12901 attagaagat gaatataagc aagtatgtaa taaagtctat acaacagtag gaaatacttt
    12961 tgtaacagat ataattgatg ttgagaaata tgattatata ttaacatgtg gtccaactcc
    13021 aatgatggaa aaattagtta agatggtaga aggtactaaa acgagaatta tggtatctct
    13081 tgaaaaccat atggcttgtg gagtaggtgc ctgtttagta tgtacgtgta aaactaatgg
    13141 aggaaacaaa aagacttgta aagatggtcc agtgttctgg ggagaggacg tgatttttaa
    13201 tgggtaattt aagtgtgaaa tttggaagtg tagaatttaa aaatccagta ataatggcgt
    13261 ctggaacttt tggatttgga aaagaatata atgagattta tgatatacaa aaacttggtg
    13321 gtataagtag caagggtctt actttaaata aaaaacctgg taacaatggt atgagagttc
    13381 atgagacacc atccggtatg atgaatagtg ttgggcttga aaaccctgga gttcaaggat
    13441 ttatagacta tgaattacct ttttttagta aactagactt agtcagaata gctaatgttg
    13501 gaggtgggac attagaagac tacttattag gggttcaaat gttaaatgac aagcctatag
    13561 acattattga attaaatata tcttgcccaa atgtcaaagc tggtggaatg gcttttggta
    13621 taaaaaatga agtggcaaga gaagttgttc gtgaggtaag aaacataacg aaactgcctt
    13681 tagtaataaa attatcaccc aatgcagaag atattgtagg aatggcaaaa gtttgtgaag
    13741 aagaaggtgc tgatggagtt tcattagtta atacttttaa agcaatggca attgatataa
    13801 aaaatagaag accagtattt gaaaatgtat atgctgggtt atctggacca gctataaaac
    13861 ctatagcttt gagaatggta catgaagtgt gtaaaaatgt aaatatacct gtaatgggaa
    13921 tgggcggaat aactaaagcc acagatgcta tagagtttat aatggcagga gctacttgta
    13981 tccaagttgg aactgcaaat tttatgaatc ctagaatagg tattgaaata atagatggga
    14041 ttaatgaatt tatggataga gaaggaataa aaagtttaga cgaaataaga ggaattatat
    14101 aaggtagaat aaatagtatt ttaaagataa aaaatataga ttaaataaac aataatttta
    14161 taacattaac atggaggaaa aataatatga gtaaagtaga tgtagtggat atattaaaga
    14221 aaagtgatgc attgttggag ggacattttt tattatcttc aggaaaacac agtaatagat
    14281 acgtacaatg tgcaaaagta ttaagatttc cagaatatgc tgctgaggta ttaagtacag
    14341 ttgttgaaca aataaaagac ttagatatag acttagtagt aggaccagct atgggtggag
    14401 taatagtttc ttatgagtta ggaagacaat taggaaaaga agctgtattt actgagagaa
    14461 aagacaatac aatggagtta agaagaggat ttgaagttaa aaaaggagca aagataataa
    14521 ttgctgaaga cgttgtaact actggtaaat caactatgga gacaaaaaga gtattagaag
    14581 ccttaggtgg agaagttgta ggtgttgcat gtatagcaga tagaactaat catgatatag
    14641 gtatgcctat atatagtgct ataaaacttg atattcaagt ttatgaatct gatgagtgtc
    14701 ctttatgtaa ggaaggaaaa ttaccagttg ttaagcctgg aagtagagag ttcaaggaat
    14761 tagggatgta ataaaaactt aattatttat agtgttactt aaaaaatgta aattttttag
    14821 agtaaaaatt tgtaatataa catataactt aaaaataaaa agcagttagc cttataaatg
    14881 aaggttagct gttttttttg ttaaaaatat atttacaaaa taagagatag tagcagtaca
    14941 atataagtat aaggtaaaag tattatatat tagggagggg taagtatgaa aaatcaatta
    15001 aatgaaaatc ataaaaaggt tgtatttttt ggagtaggtg ctgtaggagc tacttttgca
    15061 gaacaatttt ttaactctaa atatgatttt aaaattcttt gtgataatga aagaaagaaa
    15121 agatatttag aagaaggatt tataataaat ggaaaaaggt atgattttaa ttatgtaact
    15181 aaagatgagt ataaacaaga ggctgatttt ataattatag gtctaaaata taataattta
    15241 aaagaaaata taaaagaatt agatggatta gttggaaaaa atacagttat aatgtctctg
    15301 ctaaatggag ttgatagcga agagataata ggagaaagat ttggaattgg aaaaatggta
    15361 tattcatatg ttaccaatat agatgcaaag aaaattaata ataatattat acacactact
    15421 aatgggataa ttgtatttgg taacaaagat aatagtgaag atagaaaaac taatataata
    15481 actgaagtct ttgatgatgt aaatatagaa tatattttat caaaagatat tcaacgagat
    15541 atgtggtgga agtacatggt taatattggt gtaaatcaaa cttcagctat acttggtgca
    15601 ccttatggag tttttcagag ttctgagcat ttaagagaat tagcaaaatc tgcaatgagg
    15661 gaagttgttg ctatagcaca agcaaaagac atatctctta cagaagatga tgttgaaaat
    15721 tcattacata gaatactaga acattcaaaa gaaggaagaa catcaatgct tcaagatgtg
    15781 gaagctcata gacctacaga agtagatatg ttttctaaga atatctgcaa acttggaaaa
    15841 aaatatagca tacctactcc tataaatcag actttatttt atatgataaa agtaattgaa
    15901 agtagatttt aaagggtatt tgtaagaaat attgataatt attgatttta aattttatta
    15961 atgttatata ctatttaagt tactaaatat ttttaactct tcaatgaaaa tagttgctgc
    16021 ttttgacaaa gttatatctt ttggaaatat atatgagaaa tgtctgttgt agctgcttcc
    16081 aagctctatg acagacagct cattgtttaa aacaggtaag cttgtcacta gattagaaac
    16141 tattgtaatt cctaaattat ttctaacaga ttctttgaca gcataattac ttccaaaaac
    16201 catcatactt tttggaataa tttctttaac acttaaaaac atatctaaat agtctctggt
    16261 tccagaacca tcctccctga ctatccattt ttggtcttga agtttatcaa aactaaaatc
    16321 ttttaataaa tgactattgt atggaagtgc taaaaccatc ttatcttcaa aaaaatattc
    16381 ttgaataaat gaaggggaag agcaagtgcc ttcaataaga ccaatgtcta aaatataatc
    16441 cttaacatga gaagatacga ttgatgtatt ttttataaaa acttctacat ctatgtcagg
    16501 atacttttga gaaaataatg ctaaaaaatt tggtagaata tattctccaa tagttaaact
    16561 tgcaccaatc tttaagtgac cagttatagc atctgaaact tggcttacat catgataagt
    16621 aatatttaaa agatttaata tttctttagc tcttttgtac aatatttgtc cactttctgt
    16681 tataaaaatg gttttttgtt taatagacct gtttataagc acaactttaa aataattttc
    16741 tagatttttt atgtgtttac ttacacttgg ttgtgataga tttaagtatt ccccagcttt
    16801 agtaaagttt ttgtattcaa caacagctac aaatgttttt aattcttcaa acaatttttt
    16861 gtctccttca cctaatgaaa ttttacattt tttatatact ttctacagat aattatacta
    16921 tatataataa ccattaaaaa cattaatcat tacgatatta tatatttatt ttacttatgg
    16981 ttattacaat tatatactat tgctatgaag aaaactatat taattataag gtaggtatat
    17041 tatgttaaag aaaaaaagca gtttgacatt aaaaactata agggaaatat taccaggact
    17101 gtttatatca gtgttagtag gttatattag tatatttatt tctattttaa ttcctaaggt
    17161 aggggcagca tcaatttcta tatttttagg tatgtttgta ggaaacctat ttttaaatca
    17221 aaaggtattt caaaaaggtt ataaattttc agagacagat ttgttatcat attcaatagt
    17281 actattaggg gcaacactca gtgtatctac cttaatagac ttaaaagttt caggaatttt
    17341 atttataata ttgcaaatga caataacaat aatagctgca ctttatatag gtaaaaaact
    17401 aggatttgaa gaaaacttta gatttctaat ggcaagtgga aatgcagtat gtggttcttc
    17461 tgccatagga gcaacagttc cagtggttaa tgcgacagat aaagaaaagg gaattgcagt
    17521 aactattgta aatgttactg gtatattcct tatgttttta cttccaataa tatctcaatt
    17581 tttatatagc catgaacttg taaaaacttc agcaatgata ggtggaactt tgcaatcaat
    17641 tggtcaggtt gtagcaagtg gagcaattgt tggagaaaat gtaaaagatt tggctactat
    17701 ttttaagata gtaagagtaa tatttctagt tgttgttgta ttagtatttg gacatatgaa
    17761 aaatcagtct aatagggaaa tccttgaaga agaaaaggat gagataaaaa agaaaaaagt
    17821 aactatacca tggtatgtaa ttggattctt tataacttgt gcactttttt caatgaacat
    17881 tataccaaaa gaagtatctg tgttgtgcaa agaaataagt aacaaactag aaataatagc
    17941 tttagcagca attggattaa aagttaatgt aaaagattta gtgaaacaag ggaaagaagt
    18001 ttctttatat ggtttatttg taggtacagt acaagttgta tcagctgtag ttttaataaa
    18061 aatatttata tagcacaaaa atagtatttg taatattaat ttgattaatt aaaataatat
    18121 gatactaata atttataata taaataaaaa atgaatttcg ataagtttaa gtgggtataa
    18181 acttatagaa attcattttt tatttaaggt aaaaatttaa agtaaaatat tattttacat
    18241 aataataacc ttataaattt tgaaattact tatctttgtg ttaaaataag taaaatacac
    18301 atattaaagt taagttttta agtaaataaa caaaatgaaa atataaatat taaggagatt
    18361 tggtatatga atgtttatga aaaaggtaat ggagttatac tagaaggagt aacagatttt
    18421 gacccagtac atatatttga gtgtggtcaa tgttttagat ggcacaaaca agaagatggc
    18481 tcatacactg gagttgcaag ggggagaata ttaaatgtca aaaaagagaa tgataaaata
    18541 tatttaaata atacgaattt aaaggagttt aacagcattt ggtataatta ctttgattta
    18601 ggaactgatt atacagaaat aaagaataag ctaaaaaata tggatgaata tttgaataag
    18661 gctactgaat ttggatgggg aataagaata ttaagacaag atggatggga aatgcttata
    18721 tcatttataa tttcctctaa taataggatt cctatgatac aaagagcgat agaaaattta
    18781 tcaagaaagt ttggtaagta tataggtgaa tatgaaggta atgaatacta tgcattccca
    18841 acaccagaag aactaaataa ggcctcacaa gaggaaataa gagcatgtca aacaggtttt
    18901 agagataagt acataaaaag tactacacag gcagttatag agaataatga tgaggtatct
    18961 gaatatacaa atttaagtac agaggattgt agaaaagagc ttttaaaatt taatggagta
    19021 ggaccaaaag tatgtgattg tattgcatta tttggtatgc aaaaatatga ttcttttcca
    19081 gttgatgttt gggttaagag agttatgcaa gaattttata tagatgaaga catgagttta
    19141 cctaaaatga gaacttatgg aatcgataaa tttaaagaaa tgtctggatt tgctcaacag
    19201 tacttatttt actatgcaag agaactcggt ataggaaaat aaattaaggg ggagaaatta
    19261 tgggagtaat aggaacaata tttctgttct atttaattat atcatatcta gctggagcca
    19321 taatttctgt gattatattg cttgaaaata gagaccctgc aaaaacaatg tcttggctat
    19381 tgatgtttat tatatttcca ggtgtaggtt taatgatata tgctatttca ggtagaaata
    19441 ttagaaaaag aaaattattt aagactcaaa aactagctaa taatataaaa gaaaagaaac
    19501 tatttgatac attagaaaag ataacagaaa tagttgaatt agaaaaagaa tctataaaac
    19561 aaaataagct tttaagagat gaagaggatg gtagttatag aaaaagggta ataaatatgt
    19621 tgttaaagac tggtatgttt ccctttacta aaaataataa agtggatgta tttgtagatg
    19681 gaaatgaaaa gtttaaaaga cttatagaag atataagaga agctaaagac catattcatt
    19741 tagagtactt tatcatcaaa gatagtgaaa taggtagggt gttaaaagaa gaacttataa
    19801 aaaaggctaa agaaggcatt aagataagaa ttttatatga tgatgtagga tgctggagat
    19861 tttggtttaa tagaaaattt ttccgagaaa tgagggaagt aggtatagaa attgcagcat
    19921 ttttacctac aaaatttcct ataataggag gtaaattaaa ctatagaaat cacagaaaaa
    19981 ttgttgttat tgatggaata attggatata caggtggaat aaatatagga gatgaatatt
    20041 taggcaaaaa tgataagttt ggatattgga gagatactca tattaggatt aagggtattt
    20101 ctgtatacat gcttcaaatg acatttctga ttgattggta ttatacgaca aaagaagtat
    20161 tagtgactaa aaattatttc ccaagtgtag ggaatgttgg tgaaagtatg atacaagttg
    20221 ttgcgagtgg tccagacagt gactgggaag atattcatta tgcttatttt tctgcaatat
    20281 gtcaggctag aaaaaatgtt tatatagaaa ctccatattt tattccagat gaaagtctac
    20341 taaaagctat aaagagtgct gctcttagtg gagttgatgt gagaataata tttcctaaaa
    20401 ttgcagacca caagatagta aatatagcat cttattcata ttttgaagaa atattaagag
    20461 caggtggtaa agtttattta tataataaag gatttataca ttctaaagtc gtaataatag
    20521 atgataaaat tgcttctgca ggtacagcta atatggattt aagaagtttt atgcttaact
    20581 ttgaggtaaa tgcatttatc tatgatgaag aagttattag ggtaatgaca gatgatttct
    20641 ttgaggattt aagtcactgt gaagaactta atttggaggt atttaagaat agaaatatca
    20701 tacaaaaaat caaagaatct gtagcaagat tattttcacc aatattataa aaaattatta
    20761 aaaaaggtat tgaaaattat gtgtgattgg tatattataa taattgttag cactctatta
    20821 gatagagtga taataaataa aaagtatata tataaatcta catatataag tagtattaat
    20881 ttaaaaataa ctaaaaacat aggcgaacta gtctatactt aatattttag gaggcgtgaa
    20941 taatgaaaat aagaccatta gctgacagag tagtaattaa aaaagtagaa gcagaagaaa
    21001 aaactgcaag tggaatagtt ttaccaggag cagctaaaga gcaacctcaa atagctgaag
    21061 ttgtagaagt tggaccaggt ggaatagttg aagggaaaga aataaaaatg gaattgacag
    21121 tgggagataa ggttatattc caaaaatatt ctggaacaga agttaagata gaaggacaag
    21181 aatacacaat actaagacag agtgatgtat tagctgttat tgaataaata tagaataaat
    21241 ttattaggag ggatttaaaa tggctaaaga aattaaattt tcagaggaaa caagaagagc
    21301 tttagaagct ggtgtaaata aattagcaga tacagtaaaa gtaacattag gacctaaagg
    21361 aagaaatgtt atattagata aaaaatttgg ttctccactt ataactaatg atggagtaac
    21421 tatagcaaaa gagatagaac tagaagatag atttgaaaat atgggtgctc aattagttaa
    21481 agaagtagca actaaaacta atgatgtagc tggagatggt actacaactg ctacagtttt
    21541 agcacaagct ataataagag aaggtttaaa gaatgtaaca gcaggggcta acccaatact
    21601 tttaagaaaa ggaatacaaa aagcagtaac agtagcggta gaagaattaa aaaatcaatc
    21661 aagaatagta gaaacacaag aggctatatc tcaagttgct tctatatctg ctggtgatga
    21721 agaagttgga aaattaatag cagaagctat ggaaatagta ggtaaagatg gagttataac
    21781 tgttgaagag tctcaaacta tgaatactga attagatgct gttgaaggta tgcagtttga
    21841 tagaggattt gtttctgcat atatggttac agatgtagat aaaatggaag cagttttaaa
    21901 tgacccatat atattaatta ctgataaaaa aatatctaac atacaagaat tattaccagt
    21961 tcttgaacaa atagttcaac aaggtaaaaa gttattgata atagctgaag atgtagaagg
    22021 tgaagcatta tctacattag tagtaaataa attaagagga acatttgatg tagtagcagt
    22081 taaagctcca ggttttggag atagaagaaa agaaatgctt caagatatag caatacttac
    22141 aggtgctcaa gtaatatcag aagaattagg ttatgattta aaagaagctg atttatctat
    22201 gctaggtaga gcttcatctg ttaaggtaac taaagaaagt actacaatag tagatggttc
    22261 tggagataaa aaagctatag aagatagagt aactcaaatt aaacatcaag tagagcaaac
    22321 tacttcagat tttgatagag agaaattaat ggaaagatta gctaaacttg ctggaggagt
    22381 agctgttgta aaagttggag ctgctacaga agtagagtta aaagaaagaa aattaagaat
    22441 agaagatgct cttaatgcaa ctagagcagc tgtagaagaa ggaatagtag ctggtggagg
    22501 aactgctttt gttagtgtta taccagcaat aggaacacta attgagagtt tagaaggaga
    22561 agttaaacta ggtgctcaaa tagttaaaaa agcgttagaa gagccattaa gacaaatagc
    22621 tataaatgct ggtcttgaag gtgctgtaat tgtgcaaaat gttgttaagt ctgaagcaga
    22681 aactggattt gacgcattga atgaaaaata tgtaaatatg atagaagctg gtatagttga
    22741 cccaactaaa gttagtagaa gtgctttaca aaatgctgca tcaatagcaa gtactttctt
    22801 aactactgaa gctgctgttg ctgaccttcc tgaaaaagaa gatgcaggaa tgccaggaat
    22861 gggtggcgga atgcctggta tgatgtaatt taaaaaattt aaaatataaa ttttaatata
    22921 aagaactatt tcgacttaga ttttaaactc taagttgaaa tagttctttt gtatatatct
    22981 aatttttgta tatctataaa ttcaatacac atatttagat aatcagtatc tagtttgtaa
    23041 taatatttta gagtagtatt gttatttttt aggttatgat tttagatata tattaattaa
    23101 ggtataattg ttgatagaga ataaatcaaa tttaaaagga tgcgataata tggacttaag
    23161 aaaattactt gaagaagtta aaaatgaaaa tattgatata gattttgcgt tagaaaagtt
    23221 aaaagattta ccttatgaag accttggata tgcaaatata gaccatcata gagaattaag
    23281 aaatgggtat ccggaagtta tttattgtga aggtaagagt gatgagcata ttttagggat
    23341 tattgataaa atgaatcaaa aaagttctaa catattgggg acaaggtgca gaaaagaaac
    23401 ttttctgaaa attaaagaaa tctataatca tgctgagtac gaagaggcat ctaaaattct
    23461 taagattcaa aatcatgata tagagaatat aggaaaaggt aaaattgtga ttgctacagg
    23521 gggaacttct gatataccag tagcagacga agcttatcat acagctaagt ttttaggtaa
    23581 tgatgttgat agaatatatg atgttggagt ggcaggtata cataggcttt taaataaaag
    23641 acataaaata gatagtgcta gagtaatagt agccgttgca ggtatggaag gtgctcttgc
    23701 aagtgtaatt ggtggactgg ttgatgttcc agtaatagct gttccaactt ctgttggata
    23761 tggagcaaat tttggaggat tagcagcatt actagctatg ttaaatagct gtgcatctgg
    23821 aatatctgtt gtaaatattg ataatggatt tggagcagga tatttagcat caatgataaa
    23881 taaactgtaa atacattgat ataaattaaa caaaactata taataaaatt taatttctat
    23941 tatattttta ctattaaaat tgaggagaca tatatgagtg aaaaaatact ttattttgat
    24001 ataataagcg gtatatcagg ggatatgacc cttgcaagtt tattaaattt aggtgtgcct
    24061 aaggaaattt ttttggagga aattcataaa ctaagaatga gcgatgaatt taatataaac
    24121 atcagctcga aaactgaaaa tggaatagta ggtacaaaag tagaagtaat tacaaaagaa
    24181 aaacatacac atagaaattt agtggatata tttgaggtta tagataaaag cactctaaac
    24241 gaaaatgtaa aatctaaagc aaaaaaaata tttatggtaa ttggagaagc agaagcaaaa
    24301 gttcatggaa ctacaataga caagatacat tttcatgagg taggggctat agattcaatt
    24361 gtagatatag taggagcttc tatattagtt gacttacttt gtgtagataa agtttgtgct
    24421 agtacagtgt ctgttggttc aggatttgta aaatgtgaac atggaattat acctatacct
    24481 gcacctgcaa ctatagaaat tttaaaaggt gtgccaatta aattaaataa tgtaaatgga
    24541 gaatgtacaa ctccaacagg agctgcaatc ataaaagtct tgtgtgatga gtttgtagat
    24601 gagcttgaat tttctccaaa gcaaattgga tatggtatag gtcataagaa gtttgaagta
    24661 ccaaatatac tcagaactgt attaggtgaa aaaaaaaaga agaattaatt tatgaaatta
    24721 gtgcaaacat tgatgatatg tcttccgaaa tctattctta tttgtatgaa aaaatattag
    24781 atgagaaagc attggatatt tatacagaga gtatttatat gaagaagaat agaccagcaa
    24841 caaaagtatc aattttatgt aatgaatcag atttagaaaa gtttattaaa atattacttt
    24901 tagaaactag tacttttgga gtgagatata atgcatataa tagagaaatt ttagagagaa
    24961 aatttgtaaa attagataca aaatatggag tggttacagt aaaactaggg tattataaag
    25021 gaaaactagt caaggttact ccagaatata atgaatgtaa aactatagca aaaaatgaag
    25081 atattcctat aaaaaaagtg tttgctgata taaattttag aataaaagaa gaatttagtg
    25141 aaaacttatt gacataagta ataaattttg ataaattaat attcagcctt attaaataaa
    25201 agtaaacaga aaaaaatata taaaatataa actcactcgt atatgctcag aaatatggtc
    25261 tgagagtctc taccaagata ccgtaaatat cttgactatg agtgaaatta ttataccaaa
    25321 agacctagtt aagtaaatgt gtaggctgag ttatactccc tatgtgttgg ctataagata
    25381 aaggtatttt ggaagcctgt atagtaattt cacttttgct agaaattatg gaagttacta
    25441 tacaggtttt ttgtgtaaaa agatttaata taatttagac tgtattgtgt taaaataaat
    25501 atataaaaac tatattatac aaggagagat gtgaatttat gaaacatgaa ttagtacttg
    25561 taatagattt tggaggacaa tataatcagt tgatagctag aagagttaga gaaaacaacg
    25621 tatattgtga aatacttcca tgtactgcaa gcatagaaag aataaaagaa aaaaatccta
    25681 aagggataat atttacaggc ggtccaaata gtgcgtattt agaagattct ccaacaatat
    25741 caaaagaaat atttgaacta ggagtaccaa tacttggaat atgctatggt attcaaataa
    25801 tgtctcatgt attgggtgga gttgtaagaa aaggtaataa acaagaaaag gaatatggaa
    25861 aaacatctat aacttatgga aaatcatcat tatttgaagg aataactaca aatagtgtat
    25921 ggatgagtca tacagattta atagaaaaag ttccagaagg atttactata gttgcaaata
    25981 ctaatgattg tccagtagca gctatggaaa atgtagaacg aaacctatat ggagttcaat
    26041 tccatccaga ggtagaacac tgtttggaag gggacaagat acttacaaac ttcttatata
    26101 atatttgtaa agtaaaaggt gactggacta cagattcatt catagaagat aaaataaaag
    26161 aattaaaaga aaaaataggc gataaaaaag ctttatgtgc tttaagtgga ggagttgatt
    26221 cttctgttgc tgcagttctt attcataaag caattgggga caacttaact tgtatatttg
    26281 ttgaccatgg tttacttaga aaaaatgaag gaaatgatgt agaaagaata tttagagaga
    26341 aatttgatat aaatttaata agagttaatg cagaagatag attcttatct aaattaaaag
    26401 gagtttctga accagaagct aagagaaaaa taataggtga agaatttata agagtatttg
    26461 aagaagaatc aaataaatta ggaaaaatgg atttcttagt acaaggaaca atctatccag
    26521 atgttataga aagtggacat ggaaatgctg ctactataaa gtctcatcat aatgttggtg
    26581 gaatcccaga agatgtagac ttccaagaaa ttgtagaacc attaagagag ttatttaagg
    26641 atgaagttag aaaaatagga ttagagcttg gtatagaaga aggattaata tttagacatc
    26701 ctttcccagg accaggtcta ggaataagag ttataggtga tgtaactaaa gaaaaatgtg
    26761 atatattaag agaagctgat gctgtttata tggacgagct tagaaaagca ggtttataca
    26821 gagaaatatg gcaagctttt gcaacattac cagatgttaa gactgttgga gtcatgggtg
    26881 atgaaagaac atatgcttat ttagttggtt taagagcagt tacttcttct gatggaatga
    26941 cttctgactg gtataagatg ccttatgatg tattagaaag aatttctaat agaataataa
    27001 atgaagttga tggagtaaat agagtagttt atgatataac ttctaagcct cctggaacta
    27061 ttgaatggga atagtaaaca aaaaagtcgt aagctttgtg atttcaaggc ttgcgacttt
    27121 ttgaaaaatg cttatgatac taaaatgata ctatatattt aaattatcta gtttttgagc
    27181 aacttcaagt tgcttattcg ggtataaatg cgaatatgta ttccaagttg tttctacttt
    27241 ttcatgcccc aatctttccg ctatagttaa tatatttaca tccatattca ctaataacga
    27301 cgcatgagaa tgtcttaaat catgtactct aattcttttt acattagata acttacaaca
    27361 tctatttagt tctttagaaa gataactttt agcaaattta aatattcttt cattatcttt
    27421 taagtcatac agcttagata gataatcttt tatattatta tataaaaaac atgggatagg
    27481 gacaacacgt ttacttttag aagttttagg agaagaaaca atatcctcac catttaattt
    27541 tatgtaactt ttttcaacac ttattttatt ttcaaaaata tcttttggag taagagctaa
    27601 taactcccct agtctaagac ctgtccaaaa taaaatttca aaagctaatt taggttctgg
    27661 tttcttttca aattcaataa attttttgaa ctcttctaat gtccaaaaat tcatttcatc
    27721 tgcatttttt ttgcctattg tacctgctaa atgagcagga ttagaaggta agttataata
    27781 tttaactgca taatttaata cagcaacaag ctggttgttt atcgttttta tatatgtttg
    27841 actgtaatca ctttttaata attcattttg ccatttccgt atatgtgtgg cagtaatttc
    27901 atttattttt aaacttttaa aaaaaggtaa aattctaaag tttattaaat actttttagt
    27961 ttctaatgta gataatttta atctagaaga catatcgtgc atgtattctt ctatgagact
    28021 ttcaaaactc atatcagtac tcattttaga tttatttaaa aattctcttt caaactctag
    28081 agcttctttt ttagttttaa aacctctctt aattttcttt ttcctatccc cattgaagtc
    28141 tgtaaaataa aagctagcat accaactttt tcttcgttcg tctttgtaag caggcatttt
    28201 agacacctcc aattatgtca ttttatatta caataattat aacatgttag atatgctatc
    28261 taaataattg ttttattttc ctcttctttt tatttcttga aacttgtaat atttacacag
    28321 ttctaagaag tcttcttcta gtgctataga taagtctaat atcgtagata tacctatatc
    28381 tttgtactct tgattttcca gctttgatat ataacttctg ttacgtccca ttttttctgc
    28441 taattctagt tgtgtcattc ttttcttttt tcttaatttt ttcaacattt attaaaatcc
    28501 accttttaat tatttttatg acatttttgt aattaatagt ttgtgtaatt tcttgtaaaa
    28561 aatgttcctc gttagaacat tttttggtgg gaaaatgtgt taaaatgtaa gtaagaaaag
    28621 cgcattaaaa gcactataag aatagtgctg agatgctaga gtttaaagaa agaataaatt
    28681 ttatttaaaa gcttataaat ataaagtaaa taatttgtaa attaaatcta agaataatgt
    28741 aaaaaatgca ataaaaaaat aaaaattaaa attatgaaaa ataaagctag ccgactaact
    28801 aaaaatagaa atatacaaat aatctaaaat actagaaata aaaaaataga agtgaatttt
    28861 taaaatcaaa actaaaatct ctatattagt caagttgcaa gataatataa atttatatat
    28921 aatatattta caaagaaaat cttagaaatt ttaaatatta tatttgttgc aataaatata
    28981 tcaagtctat aagttaagga atttttatac cattttttac gaacataagt tctgaaaagg
    29041 gatataaaat ataatattat aaaaagaagg tgattggcta aattttttac atatttaagg
    29101 ggcaaggaat aaatattata aattataaga gggtgacgca aatgggagat tcagattgtt
    29161 ctaaaatgtt ggcattttat gaaattatga aaatgttaga gactattgat gaaactaaat
    29221 tttataattg taaagaagaa ataaagtcag agtttaagca tataaaaaaa gaggattgaa
    29281 tcctcttttt tatatttttt tatgcttatt ctttattttt agtattttgc tcctccaaaa
    29341 aaagttttgc tatctttaaa gctttatttt tagaatcatc atcaagttca ctaaaaatat
    29401 caagtatttc tttcatgtca tcagatggat ttagcttttt aataagttct ttttctgtga
    29461 tattagaaat attaattttg atattagttc tacctaataa atagtcagtt gatatatcta
    29521 aagtatcagc tatatgtctc acaacatcaa gcgctgggct tcttttacca gtttcatatc
    29581 cgttataagt gtttgctggt aaacttaatt tattagccat ctctttttgc attaatccga
    29641 gttcttctct ctcttctctt aatcttttag aaaatatatt gctttcatct ttatacattg
    29701 taattgtccc cctcttaaaa actataacga atgtaattac tcttattcta ctacaaaata
    29761 cgcattttgt gattttaatt cgcaaaaagg aagaaaaaaa caaaaaacgt attgacaatt
    29821 cacaaaacgg agtatattat ataaatatag aaacttcaaa ttgagaataa aaggagtgat
    29881 atatattgaa aaattatata ttgaaatctc ttagagtaag acaaggattg agacaaagag
    29941 atttagcaaa aatattagga atgaatccca gcacttactc aagtaaagaa aatggcgata
    30001 ggcgattcac agtaagtgaa gcaataaaaa tatcagattt ttttaataca gatttgagag
    30061 atattttttt aaataaataa ttcgcaaaat gtgaataaaa aggaggtaga taaacatgaa
    30121 taacttacaa gtaatagaaa aaaataacga aagagtttta actacacagc aactagcaga
    30181 tgtatatgaa acagatgcaa gaaatataag caacaatttt aacaataaca aagatagatt
    30241 tattgaaggt aaacattatt ttttattgca aggtgatgat ttaaagcatt ttaaaggtat
    30301 tcatacagaa tatgaaaacc taaaatttac ttcaaaaatg tatctttgga ctgaaagagg
    30361 agcaaacaga cactgtaaaa tattagatac tgataaagct tgggaacaat tcgataattt
    30421 agaagaaaca tatttcaaag ttaagcaaca taaaccatct tgcatagaag atgttttgat
    30481 agaaagttta aaagaaatga aagatttaag actacaagtt aaccgagcta ataacattgc
    30541 attagaagcg aaggcagaag ttgaaacaat aaaagatgta gtttcattag actcaaatag
    30601 ttggagaaca gatacacatc aattaattgc aaggatagca aaaaaacaag gtggttttga
    30661 acatataaac atgcttagaa cagaaagcta cgaattacta aataagcgat ttggagttga
    30721 cctacataga aggttaatca ataaaagaag aaagatggca gaagaaggtg tatctgaatc
    30781 caaaagagag aaagttaaca atttagatgt aatacaagat gataagaaac tcatagaggg
    30841 gtatgttgct attgtaaaag atatggcttt aaagtacgga atatcaagtg atttaagcaa
    30901 gaattaggtt aaataaaatt agcactttga aaattaaata cagaatattc aaaagaggtg
    30961 agatagattg aatagtaaaa agaaatatac tctaagtatt acagaagaat tatatattaa
    31021 atgcaaagaa aaagctaatc aaagaggtat gtcagtaaat gagtatatac tatcagtgat
    31081 tagcaaagtt ttataaatgt tattcttcaa tattaacctt tatttctcct tttatttgtt
    31141 cgtaattttc aacatgtttt ttaattagtt gttcgatttc tttattagca gagcgacctt
    31201 cactttctgc aatatactta attttttcaa gtaaaatttt atttattctt aaagtgtatt
    31261 taggcaatgt agatgacata ataatacctc ctttttaaag tctaaatgat gtcattatta
    31321 tatcataaaa ataattaaag aaagagggga ttgaaatgaa acatgagcaa acaacgcttc
    31381 gtataccaaa tgacttgtac aaagcgttga cagatttaag caatgaaata ggaacaccta
    31441 ttacatctat tataataatt gcgtgttggt tgtatatatc aaagataaat taaccaatca
    31501 gatatgcaaa atgaatgcac agcattattt attagagaat tgattgataa attattttct
    31561 ttagctgttt tctctagcaa ctcttttaga acaacaggaa tcctaagagt agaacgaaca
    31621 ctgtcctcac ttttatacga gactgattta agttcattaa cttttgaatt tctaataatg
    31681 tcattaatag catatagaat aagcgaagat ttaagaatac ctgtttcaca agaaattttt
    31741 tctaagtttt cgtttaatgg tgtatatatt cttacagtaa tagtagtcat tttgacacct
    31801 ccttaatgac attatacaaa agatatttaa aaaagtcttg acagtaaaac agtgtcataa
    31861 tataatggat atagacagtg aaacggtgtc aaagagaggg ggaataataa tggagaaagt
    31921 aagaatgacg gtaagactcg tcccaaaatt aaatcaatat gtacagaata tagccaaaga
    31981 atgtggaaaa agtaaaaatt ctattattgt ggatgcatgt tgggagttta ttgagaaaat
    32041 aaaaaaagaa aataaattca atgtagaaag cgaggaataa atatgaataa tctacagata
    32101 tttgaaaaat tggaatttgg tcaaataaga atggcagaga ttgataataa gccttacttt
    32161 gtaggaaaag atattgcaaa gtctttaggt tataaaaata ctaatgatgc aattttaaga
    32221 cattgcaaag gggtagtgaa acacgagggg tttaaaatta atggtattaa ggttgctttg
    32281 ataactgagg gtgatgttta cagattaata gtaggttcaa atcttccaaa tgcagaaaaa
    32341 ttcgagagtt gggtatttga tgaagtactt ccaagcataa gagaaacagg taaatatcag
    32401 ttacaacaag atgtaataac agaacttaca ggaactatag gggatttaaa aggaacaata
    32461 agagaatata aaaagatgtg taagataact tgttctaaga aacaacagta ttccagatac
    32521 ataaaaaata gattagatat agacaaagca aataaagaat acaaccaagt aaaggcgaga
    32581 ttattcctaa ttctcggtgt tgagaaatgg gaagatatag actttgatac atctaacaat
    32641 ctaatacaaa ttatagatga ttgtataaga gttataaagt cagagagacc atacaagcaa
    32701 ttaagttact ttgaaaacta aatacagaat attcaaaaag aggtgattag atacaaaata
    32761 ataataagcc tgtctaaaaa gttataaaag agcaggcata tagtaattac tctgtatcat
    32821 ttcctttttc taacatttta tcagctaaat cctcaacttt acttataaat ttgatttggt
    32881 tacgctcatc gaatttatgt aatagagata aaatttcctg ttcgttatca gttggcttgg
    32941 atattttaag aatatctgct gaatattctt taccttttag gatataatcc acacttatat
    33001 ggaatttttc cgaaataata agcacatcat caatggtaaa attagattta cctctgcgta
    33061 tatcagtaac tttacctcga tttttccatc ctagaagtga gattatttct ttgtcagata
    33121 gcttattttc aagtgttagg aagtctaaaa tattttgatt ggacataaaa tctacccctt
    33181 tcaaactata aaatataaaa agtcggaaaa attccttgac tgttggaaaa aatccgatta
    33241 taatataact ataataacaa ttacttacga caacaaattg ttatacaaac ttaattttac
    33301 cacaaataaa cacactaata aagaaggtga taataatgaa taaaaaatgt ttaccaaaat
    33361 ggagcaagga agttaaaaaa gccatgatag atagagattt gaaactagat gatttatcag
    33421 aggagttagg attatcaaaa tatcatctat cagcagtaat taacgataga cttaaaagtc
    33481 caaatgcaaa agaagcaatt tgtaaatatt taaaagtaaa aggttaatta tagtataacc
    33541 tttcaaagag gtgatttgaa tgtcatatga ataccaaaat atataccaaa aaggaagaga
    33601 aaataccaat ttaacacaag aaaaagcatc agaactacta gacatatctg tagagagttt
    33661 aagagcctac gaaaatgaca agaggatacc aaacaatcaa atagtagcaa agatggtatc
    33721 tatatataac aataatttgt taggctatga acatgttaga aggactacag aagcaggggt
    33781 aatgttttta ccaaaactag aaatgaaaag tctttcaagt ataactctaa aattacataa
    33841 agaaataaaa gattatttaa aaaaagaaga tgatttcata gatatagttg aagatgatgt
    33901 aattgacgca gaggaagaag aagtttggaa tgatgttatg gaaaaattag agggtatata
    33961 tgaagctatt ttaaaattaa aactttcaag aaatacaaaa atatcaaagg aggtataaat
    34021 atgaaagatt taacaatagt aaaagttaac aataaactaa caactgatag cagagatata
    34081 gctttaatgg ttgaaaaaga acacaagatt ttgctaagag atataagaaa ttatataaat
    34141 cagatggaag aagctaataa aaacatgagt acagatttgt acccatctga ttattttatt
    34201 gaaaatactt acttggatga ttataaaaga gaaaagccat gttatgcaat aacaaaaata
    34261 ggttgtgatt ttatagcaaa taaaatgaca ggaataaaag gaactgcatt tacaggaaca
    34321 tatacaaaaa aattcgagga aatggaacaa gaattgaagc aacagctaaa gtgtagttat
    34381 atgatagatg acccaatcga acgagctaaa cgttggatag aagaacagga agaaaatcaa
    34441 tctctaatta agaaaaaaga caacataata caattacaac agcctaaagt tgagaaatgg
    34501 gaaagatttt taaataatga aggtcttaca acaatagaag atttttcaaa gacactagca
    34561 ataaaaggtt atggaagaaa caatatgtat aaattattga gagaaatgga gtatttaaag
    34621 aaagataata gcccttacac aaaatatgta gagcaaggtt tatttacaag aaaaccaagt
    34681 ggaacacaca tagaatacgg gaaagtaata gaagattaca agacattttt aactagcaaa
    34741 ggtatagata aaataatgga aaaacttttg aaacttggag ttataaagca atcaagcaat
    34801 gtatcttatg ttgagcaaaa gcagttgtca atattaagtt aaataactgt agcactttag
    34861 aaattaaata cagaatattt tgaaatatat tgttttaatt aattattaac taggaggttg
    34921 ttaaatacat gaaaaataat acaagtgatt caagagtaag atatttttgc aagtgtccat
    34981 actgtgggtt tgataatgag gtagaagtta aaaaaggatt gaagcctaag atatgttgca
    35041 tgtgtacaaa agaagttgag tatgaaaaac tggagcaaca aagtgattca gaaaatatag
    35101 aaattaaagg agtgtgtaat taaatgaaaa tttcatttga aagtgtagtg aacaatgtaa
    35161 ataatgaaac agaattaata ttatcaaaag aagagttaca aatagctaaa aggatactta
    35221 atatattgaa tgaaaatgaa caaagtatcc tttcctcaaa agatattcta gatttttgca
    35281 aagaagctct taaatataat ttagtgccta cgtttgttta aagacactga gaccatcacc
    35341 tttagaaaaa ctattattga cttctgaaag tttcaaaaag atttcatggt aatgttttaa
    35401 aagttcttct tcagaagaat ttttaaaatc atattttttc ttaagaattt ctaaagtaag
    35461 agtatgtaat atatctttac tgaactgcat aatatcacca actttcataa aaagatatag
    35521 gatatatcct acaaatatat tatatcaaag gaggaaatta atggcaatta atgacaacat
    35581 aaataaaatt ttaagagata gaaacataaa agcatggaaa ttagcaaaag aaataggagt
    35641 agattcagga aatttatatt caattttaag agggaaaaat aaaaatccaa cgatagatac
    35701 attgataaaa ctagctgatt atttagatgt tacattagac gaactagttg gaagataaaa
    35761 attaaataca gaatattttg aaagtaggtg ttttagatga caaaagtagt agctaaagaa
    35821 caattatttt atagagcaaa agatgtagct aaattcttag atatatgcga agcaactgca
    35881 tacaaaataa ttgcggaatt aaatgaagaa ttagaaaaag aaggttttaa gactttttct
    35941 ggcagggtat caattgctta tttcaaagag agatattgct ataagccaag aaagggggtg
    36001 atttaattga atgtaaaggt gctgatagct tatatccagt tatgtaaaga caaacaaata
    36061 aaagcaagtt ttgaggggct taaaaaatat aacgaggagg tctaattgtt atggtattca
    36121 atttagataa actcaaagta ggaaatgcga taagaataag ttgcgaaaga tttggttttg
    36181 aaattgattg tattgtagta gtagcaactg aggaggaact aaatttagct tattatagca
    36241 aagataaggg atgtattgag tatcaagcat tgataccaga ggatattaga tatggtgatt
    36301 atattcttga aagattagct taggaggaaa taaaatggca gctttaa
//
LOCUS       DACTZW010000037        36000 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.037, whole genome shotgun sequence.
ACCESSION   DACTZW010000037 DACTZW010000000
VERSION     DACTZW010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 36000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36000
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.037"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            401..1156
                     /locus_tag="JAM15_09770"
     CDS             401..1156
                     /locus_tag="JAM15_09770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAT6798538.1"
                     /translation="MLQIKNLSKSFPNPYGEPNTIFENLSIDIEDGEFVSIIGSNGTG
                     KSTLLNIISGLIKESSGQVLLNKHNLSNLAEHRRTQIVSRVFQDPSLGTCPSMTVREN
                     LSLALNKGKLLNLRKCLRYKRDFLENLLEGVSLDLKKYLDVQVKFLSGGQRQSLSLIM
                     SCLTSPSVLLLDEHTAALDPKTSNEVIELTNKIVRGKNITTLMVTHNLKHALQYGDRL
                     IMLHKGEVVLDVKGKEKEQLTVEEILEKFEYAV"
     gene            1287..2309
                     /locus_tag="JAM15_09775"
     CDS             1287..2309
                     /locus_tag="JAM15_09775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAT6798539.1"
                     /translation="MINKKRLASLILAGALSISMLTGCSQGGDSGNSKQESNSKGKEV
                     KKIGITQLVEHPALDATRTGFVKALEKNGFKDGENIDIDFQNAQNDMPTTQSIASKFA
                     SDKKDLIFAISTPSAQAAFNATKDIPILITAVSDPVAAGLVKTLEKPGTNVSGTSDFV
                     SVDKGLELLKIFAPKAKTIGVMYNTSEVNSKVQVDALKEYASKNGFKVVEKGITTSNE
                     VNQGISSLVGKIDVLYVPTDNLVASSMPIVSKIATENKIPVIAAESGPVEKGALACQG
                     INYEKLGYKTGEMAVKILNGESVSDMPVATSDDTDIIVNEDILKALGMEKPSNENISY
                     VKTKQE"
     gene            complement(2473..3030)
                     /locus_tag="JAM15_09780"
     CDS             complement(2473..3030)
                     /locus_tag="JAM15_09780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HAT6798540.1"
                     /translation="MTEKEKMLSGKGYYANDELLVKEREYCKKLTRLFNNTLEDEYEK
                     REDILRQLFGSVGKQINVEQNIRCDYGYNIHVGENFFANYDCIFLDVCKIEIGDNVML
                     APNVQIYTAYHPIDAQLRNSGIEYGSPVKIGDNVWIGGGVIITPGITIGDNVVIGAGS
                     VVTKDIPPNTVAVGNPCRVIKKIEE"
     gene            complement(3036..4112)
                     /locus_tag="JAM15_09785"
     CDS             complement(3036..4112)
                     /locus_tag="JAM15_09785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/molybdate ABC transporter ATP-binding
                     protein"
                     /protein_id="HAT6798541.1"
                     /translation="MSLYVDIEKDLSSFKLKVEIKQEKGTLGFLGESGSGKSMTLKCI
                     AGLEKPTRGKIVLNDRVLFDSEKKINLSTQDRKVGFLFQNYALFPHMTVSQNIELGLL
                     KLSKSEKKEIVARYLDILKLNGFEGRYPWQLSGGQQQRVALARALATSPDILLLDEPF
                     SALDHHLRSNMEKELMNMLKDYKGDILFVTHDIEEAYRVCDDIIVYNKGEGLPKRPKK
                     ELFESPKYLIEAKITGCKNISKLNRLDKNTIYATDWGCELTLNREIGDNIEYVGIREH
                     HIKVLDSNEDLNEKLCFELINIVENPFIYTIYVRKTDLSNECVPIQIELEKSKMRFKK
                     GDRIYLDFPQEYLFCFRYNYNKKE"
     gene            complement(4113..4796)
                     /gene="modB"
                     /locus_tag="JAM15_09790"
     CDS             complement(4113..4796)
                     /gene="modB"
                     /locus_tag="JAM15_09790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HAT6798542.1"
                     /translation="MGTDWSPLWISLKTSILSTIITFVIGIFVSYIMANYRGKWKGLI
                     DGLFTLPLILPPTVVGFFLLLLCGKNGFIGKFLLNFDRTLIFSWTATVISAVVVSFPM
                     MYRTSRSAFEQIDNNMLSAARTLGLNEWKVFFKIAVPLAWPGIIGGLVLSFARALGEF
                     GATLMIAGNIPGKTQTMPIAIFFAVEGGDMNKAMMWVMIIVAISIAMILLLNYWSEFQ
                     QKIIGKRCG"
     gene            complement(4945..5757)
                     /gene="modA"
                     /locus_tag="JAM15_09795"
     CDS             complement(4945..5757)
                     /gene="modA"
                     /locus_tag="JAM15_09795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAT6798543.1"
                     /translation="MKKILGILGLVACLTLGTVGCNSNEDKKDDGKQEKTTKSSDSVE
                     LNISAAASLKEAMAEIEEEYKKVDSNVKLTVNYGASGSLQQQIEQGAPCDLFISAGQK
                     QMKALDEEKLLVSDTMKDLVKNDLVLISSADSSVSGMKDLTTDKVKKIAVGEAESVPA
                     GKYADEVLTNLNLKDKLKDKLVFAKDVKEVLAWVQSGNADVGFVYFSDTVNNDKIKVV
                     EKTDEKTHSPITYPVSVIKASKNVDAAKKFEEFLLSESGQKIFEEFGYKKVE"
     gene            5950..6879
                     /locus_tag="JAM15_09800"
     CDS             5950..6879
                     /locus_tag="JAM15_09800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6798544.1"
                     /translation="MDSLSSLTPVEVAELLKITKNTVYELIKRGELPSYKVGKKIRVD
                     TKDVEEYINSQKTGKVKDTHFNNKNIDINNNFKIIISGQDVILDILARSVEKKLDGIS
                     TFRSYIGSYNALYELYNGRVSIASSHLWDFETDEYNSTFVKKLLPGIPCVLINLAYRM
                     QGFYVAKGNPKEITTWEDLTKPSITIVNREKGSGTRVLLDGKLRLLNFNGKHIKGYDN
                     EELSHLGVASTVSRGIADVGLGNEKAALQVNNIDFIPLHKERYDLVIKKEDLQNPVYQ
                     TIINIINSPEFKAELQGLGGYDLTDTGKTIAKV"
     gene            complement(7040..7489)
                     /locus_tag="JAM15_09805"
     CDS             complement(7040..7489)
                     /locus_tag="JAM15_09805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798545.1"
                     /translation="MKNKNNKDKNMLNIKVLRVLGVLLILFDYTGDTLNFYNFFAKPL
                     VSGNLYKTTGTDCIVFLLFIVECVYLVGRYILKVKINWSEIIENEKGNFINNLLVEKI
                     QEESNIVYNLLNSYVLPHIYKKARVLMFKTYHMLIYIKEKYYYVNIY"
     gene            complement(7692..8672)
                     /locus_tag="JAM15_09810"
     CDS             complement(7692..8672)
                     /locus_tag="JAM15_09810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAT6798546.1"
                     /translation="MKNSFKNCISLRNKFIIISIVFLLILLIVSYIFGKLVYNSSVGL
                     EQLIKNEDIVKIFSERKDKPLEKLKNYKTSELMIQSSNNYKLESLFITSNIKTRDTMI
                     LVHGIGSSYYEMLKVAYRYLDKGYNVLVYNQRNTGNSGGDNYTFGLYERYDLDSLVKF
                     VKNKFPEGRLGVHGFSMGAGTAAMHSEINSKDDKVDFYILDSPYSEMKDAIRMGVLEK
                     QIPDILINYVVICGDLYNKFKSGFWYSDVKPYESVEKSNVPILFIHGTKDTVCNYQNS
                     KKMYDLVKHDKKDLWLIEGIGHVDGFEHDSTVYFNKIFKFIDSNVLSDKS"
     gene            complement(8877..9731)
                     /locus_tag="JAM15_09815"
     CDS             complement(8877..9731)
                     /locus_tag="JAM15_09815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HAT6798547.1"
                     /translation="MKWRDYADDVNLFEDFDKTIKPLTDEQRRKNINTLIAYFSKEVP
                     SKIYNLSNDEIKPRDILRGLLNVYPPKEIAPEILNMLHNLLLIECEERELVDVNDIEE
                     VEEGIAIWRGNITNLRADAIVNAANNKLLGCLQPLHLCVDNEIHSCAGPRLREDCDKI
                     IKKQGHLEYTGDAKITRGYCLPAKFVVHTVGPIVSGGQPSKEQEKQLLHCYKSCLNTI
                     KEIDEIKNIVFCGISTGVFGYPKKEAANLAVSRVRLWLKENPEKNLKVVFNVFTEEEE
                     EKYRRIFK"
     gene            complement(10054..11382)
                     /locus_tag="JAM15_09820"
     CDS             complement(10054..11382)
                     /locus_tag="JAM15_09820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HAT6798548.1"
                     /translation="MEKFSVVIAGGGSTYTPEIILMLLDNLDRLPLRAIKLYDNDEER
                     QNKVAKACEILIKEKDPNIEYLATTCPKEAYTDVDFCLAHIRVGKLEMRELDEKIPLK
                     HGVVGQETCGPGGIAYGMRSIEGVLENIDYMEKYSPNCWMLNYSNPASIIAEAVRRLR
                     PNSRVINICDMPIGMEHNIARIAGLKSRKHMDIRYFGLNHFGWYTSIKDKKGNELLPK
                     LVEHIKEYGFINGEEGMKNDKKDSWFETNLFTKEIVKTDLTTIPSSYLKYYLFPDYVV
                     NHSDVNYTRANEVIDGREKEVFGSCALIEKQGHSKGSGLKIGIHAEFIVDLATALAFN
                     TQERMLLIVQNNGAIENIQDDAMVEIPCIVGKDGYEPLSIGKIPTFQKGLIEQQLAVE
                     KLVVDAWIEKSYNKLWQALMLSKTVPSATVAKELLDDLIEANKNYWPKLN"
     gene            complement(11530..11859)
                     /locus_tag="JAM15_09825"
     CDS             complement(11530..11859)
                     /locus_tag="JAM15_09825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAT6798549.1"
                     /translation="MVPEMEEKVFSIISEAGDAKSDVMMSLKEIKKGDYNKAKHLLNS
                     ASEKIQTASKHHLELLSNAMNSEDSGTDFLVVHSEDHYSNALFAHSLVSELVDIFEMM
                     DPRINKN"
     gene            complement(11883..13172)
                     /locus_tag="JAM15_09830"
     CDS             complement(11883..13172)
                     /locus_tag="JAM15_09830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAT6798550.1"
                     /translation="MEALQNNLRRFLLPIAQKIEKQRHLQAIKEGMISITPIIIVGSL
                     SMLFMALNNMLPEGSAKTLLSENMDTLLIPNKFTMSLLSIYSAFFIAQALAKKYNLNH
                     VEIGMTAVVAQLVVCGQVVDGVLDTSYLDAQGLFVSILVALLVVDITKFMNDKNLVIR
                     FPKEVPSVVNKSFRNLTPMIVCIMLFTAIAAITKNVSGQPLPAIIMNFLAPAISSVDN
                     VFAVTIILFITQLLWFFGLHGAAITSSIWMPIAATYMAENATLIAAGGDPKYVFTIGF
                     YYGFLQVTGSGITLGLVYLMSRSKCKSFNSMGKVVILPSLFGINEPVIFGTPIVMNPY
                     MFVPFVFGPVLVGALNFMALKVGLVGLPIAEPPGFLPPGVAAFLMTLDWKAIVLVFAS
                     IILMTLIYYPFFKIMEKEELNKNAELATTLDDDSFDF"
     gene            complement(13188..13514)
                     /locus_tag="JAM15_09835"
     CDS             complement(13188..13514)
                     /locus_tag="JAM15_09835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAT6798551.1"
                     /translation="MNILLVCANGASTGVLVEKMKSFCSEHEKLKTKTINIEATSFEN
                     LKSYIEANDTDVVLVAPQIRFKEDDVVEACKNYKIAVGLIDTKHYGRMDAPSVMKSAI
                     ELYKNR"
     gene            complement(13649..14278)
                     /locus_tag="JAM15_09840"
     CDS             complement(13649..14278)
                     /locus_tag="JAM15_09840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798552.1"
                     /translation="MQDKILRDKKANDPWARMTTRNGFSADEIISSFQKAIRRNMVEE
                     ACEFAYELYISSPELEDKLWRRILTISVEDIGMGDPSAVIIINNLNQVRKEYSYADGD
                     RPLFFIHAIRYLCACEKDRSSDLLKNIIIKGFAMGKVPEVMDVALDKHTYRGLEMGRD
                     SFHFLNEASIVIPEKEVDNDYKERYLKILEKYKQEEVIDTAFKFNHWQY"
     gene            complement(14493..17150)
                     /locus_tag="JAM15_09845"
     CDS             complement(14493..17150)
                     /locus_tag="JAM15_09845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAT6798553.1"
                     /translation="MIYKKDKVMKVLESSYRENEKGITANQLSEKTGIARNNISTYLN
                     QLFNEGMVTKIKGRPVYYIPANLNLNKNELLDTQSELLGIKKGTKVENKIKKDSFETL
                     IGKEHSLRPIIEKCKVAMLYPTNGLHTIIYGETGVGKSMIARYMYDYSIDSGIRKNKA
                     PFVTFNCADYANNAQLLMGHIFGVEQGAYTGAESSRKGLLEIANGGILFLDEIHRLPA
                     EGQEMLFTFIDKGTFKRLGDATKERDSKVLIICATTENPTSTLLDTFNRRIPMKIEIP
                     SLRDRTMIERMELVKNFFKEESKSISISIKVHKEIIKSLLLYDCKNNVGQLQNDIKLA
                     VANGYLRYKRDNKEPVYIEKKYFDKSINEVSDDYREKSIKADEVITHGIEYFVFTSLG
                     EEEVINYNDINIINAVNTNLNKSVEMNIADASLFNNVKFKSMCESIRQIIKEDEEIDI
                     SESIFKSMAIYIKSVLDKSSSTNNIDLNQIRRNNRSEFKTALKIVGIIENEFDLFLSI
                     ETVAYITLFIVQAKQDEQNKIVNNINIIVAMHGETTASSMVKAVGDIIGKCSAISFDM
                     KLDKSYDEVIVDFKNLINNIDNKDVLLFTDMGSLNSFDEIIKKEKKCEVRVIPMVTTL
                     TVLEAVQKANMGLPLNDVYNSITNTRKYYFGTNEIQNKENLSKTIIIASHVSEGVDNK
                     TRKILEEKMSRYLDGIDIISVPYKTEKDLSLNITKLKESSNIVAVINEQRINIRGIDY
                     ISKKDIDKDENINKLKNIIKISIGYDDVVEGLKTSLKSSNYNRIFKDIKYVSDELFLV
                     FNIEKKYDKVIGLMMHLAFMVDGLIGNTREIEKLDKEKTLDYHKSLSKIKDIVSQLDK
                     KYNIEINEKECYQILLILEYAEIIEKDYQ"
     gene            complement(17509..18453)
                     /locus_tag="JAM15_09850"
     CDS             complement(17509..18453)
                     /locus_tag="JAM15_09850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6798554.1"
                     /translation="MNREKILEIKNLKQYFHLDKSTTVKAVDDISFDIYKGEIFGLVG
                     ESGSGKSTTGKTIIRLHESTGGEVIYKGNCISDKKTYKFIKKDVNKSMQIIFQDSTSS
                     LNPRMTIADIISEPLKIQGICKNKTDRMNKVYEMLKLVGLDRSYANKYPSDFSGGQRQ
                     RIGIARALSVDPEFIIADEPIASLDVSIQAQIVNLFKKLQQEKNLTCLFIAHDLSMVR
                     HISDRIGVMYNGKLVELADSNELYNNPIHPYTKSLLSAIPVPDPRYAKSRNRIEYNSN
                     GYDCSNEKSLSWIEVSDGHFVYSSKSEINKYQQNLKVV"
     gene            complement(18446..19471)
                     /locus_tag="JAM15_09855"
     CDS             complement(18446..19471)
                     /locus_tag="JAM15_09855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6798555.1"
                     /translation="MEHLLEVNNLSVSFKVEEGEVQAVRNVSFNLKKGETLAIVGESG
                     CGKSVLCKSLMRILPYNGYIKNGEVLLKSSDLVKKSEKEMEDIRGKNISMIFQDPMTS
                     LNPTISIGKQIAEAVIIHQGISKSEAKKRAIELIELVGIDNPEKRFKQFPHHFSGGMR
                     QRIVIAIALACNPDVLIADEPTTALDVTIQAQIIDLIKDLQHKIGLSIIFITHDLGVV
                     ATIADRIAVMYAGKIVEIGTVEDIFYDPRHPYTWGLLGSLPTLDSQDEYLYNIPGMPP
                     NLLNPPKGDAFAIRNKNALKIDYEKEPPMFKINDTHSAATWLLHPDAPEVDVPVRVNC
                     GRVISNE"
     gene            complement(19546..21114)
                     /locus_tag="JAM15_09860"
     CDS             complement(19546..21114)
                     /locus_tag="JAM15_09860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAT6798556.1"
                     /translation="MKLKKLKVLSLVMILSLMAGCSSGGDKDKKADTPKDGKVLVYGS
                     NDYTSINPALYEHGEINSLIFNGLTAHDENNKVVPCLAKDWKFDEATNTYTFNLRDDV
                     KWHDGEKFTANDVKFTIETIMNPDNASEIASNYEDITKIDVVNDNTIKITLKAPNTAM
                     LDYLTVGVLPKHVLEGKDIATDEFNQKPIGTGPFKLEKWDKGQSITLVKNSDYFVKEP
                     GLDKVVFKIVPDDKAKAMQLKSGELDLAQITPKDMSNFEKDEKNFKVNIMKTADYRGI
                     LYNFNSKFFKDKKAKGLPNALSYAIDRKAIVDSVLLGHGVPAYSPLQMGPYNNPDIEK
                     FEYNPEKAKQEIEKLGWKLGSDGIYEKEGTKLAFEITAGESDQVRVDMAKICAQQLKE
                     IGVDAKAVVVTETDWANQDAHLIGWGSPFDPDDHTYKVFGTDKGANYSAYSNPTIDKI
                     LQKARETEDKDEKLKLYKQFQVEMTKDMPYTFIAYIDAIYVGKPNIKGLTPDTVLGHH
                     GVGIFWNIADWTIE"
     gene            complement(21227..22138)
                     /locus_tag="JAM15_09865"
     CDS             complement(21227..22138)
                     /locus_tag="JAM15_09865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6798557.1"
                     /translation="MKPQYSDFEIVGENYILVAEDEYIETKKTLSKKIKELPYISIII
                     LSIIVIGSVFSSFIMTHEPTYMDLASSNLAPNKTFLFGTDSMGRDIYSMIWYGGKISL
                     FIGLFSTVISTVIGIVYGSISGSASELVDDAMMRFTEIILSIPSILIIIFVQAILGNS
                     NPVSMSIVIGITSWMNISKIVRTEVRQIRNSEYILAAKSMGGGFFYVLKQHLLPNFVA
                     SIMFMVVTNIGAAIGTESTLSFLGIGLPIEIVSWGSMLSLSEEALLSNRWWIILIPGI
                     FLVTTLVCITNIGNYIRKNNNKKSSNL"
     gene            complement(22122..23108)
                     /locus_tag="JAM15_09870"
     CDS             complement(22122..23108)
                     /locus_tag="JAM15_09870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6798558.1"
                     /translation="MLKDILKKLLQFILVMFLLSFIVFYMARLAPGDPLISYYGDGVE
                     RMSTQEKENAMKKLGLNEPIYSQYIKWISNASKGEFGISFKYKQNVTSVINDVYINTI
                     ILGGSGYILTFVLALLLGIFCTLHEDKLIDRIICKLGTITNCIPSFWVALVLILIFSI
                     NLSILPSSGAYSMGEESSILSRISHLILPLTVLILSHLWYYTYMIRNKLLEEIREDYV
                     LLCKAKGLNNRTIVFKHCLRNIMPSYISIMAISIPHILGGTYVVEKVFSYPGLGTLCF
                     ESAKYHDYNMLLVLCLITGALVVFGNMLAQIINNKIDPRMKYDRGDTNEATI"
     gene            23434..23868
                     /locus_tag="JAM15_09875"
     CDS             23434..23868
                     /locus_tag="JAM15_09875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HAT6798559.1"
                     /translation="MKSNYDCFRIAMLLKELYSKTMYTVEENFKENGLTHQQIIVIKL
                     VAHNQELTISQLCDEMSLAKGTVSGIISRLEQIGYIEKFKKSNDKRNTYVKFTTTGFE
                     FATNFKIKMQESFDDIFKNCDENELSDLVKNLRNILAKVKER"
     gene            23871..24269
                     /locus_tag="JAM15_09880"
     CDS             23871..24269
                     /locus_tag="JAM15_09880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03987 family protein"
                     /protein_id="HAT6798560.1"
                     /translation="MNYKLILAIVFITSALIFYTIGVFGERKAKILKKKHVIIFWLGF
                     IFDTLGTFTMSNIANSHTFEVKSALSQNLHSITGLLAIVLMLFHASWATFVLYKDDEE
                     KKKFFHKFSIVVWTIWLVPYFIGMFIGMVG"
     gene            complement(24719..24943)
                     /locus_tag="JAM15_09885"
     CDS             complement(24719..24943)
                     /locus_tag="JAM15_09885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifU family protein"
                     /protein_id="HAT6798561.1"
                     /translation="MREKVEKVLEEKIKPVLQRDGGDVELIDVNENGVVLVRLQGACS
                     GCPGATMTIKAIIENVLVSEVPGVTQVLGV"
     gene            complement(24978..26345)
                     /locus_tag="JAM15_09890"
     CDS             complement(24978..26345)
                     /locus_tag="JAM15_09890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HAT6798562.1"
                     /translation="MKEYIINNVEEIREELIDLSKKIWENPELAFEEKYASSIQKEYL
                     KSKGFKIEEVENLPTGFIASFGEGKPVIGILGEYDALPELSQCVSAERKPLVEGKAGH
                     GCGHNLLGVAGVGAVVSIKKLIEENKFNGTIKYFGCPAEEEGGGKTVMCINGCFDDVD
                     CAFTWHPFDINAPWRGGSLANLSVKFKFKGITAHAAQAPHNGRSALDAVEIMNVGANY
                     LREHVIDSIRMHYVITNGGGRPNVVPGFAESWYFIRGKKARDAEHVLDRLIKVAQGAA
                     MMTETEMEYKVTDGIYDYIPNQCLTDLVYDNMVFVGCPKNTPEEEEFAKKLCDTLTRE
                     ERLGVATSLQNDKSIVESYIHKEIVDGDKDKGLAGSTDVGDVSYVIPVAQFAMAAWPV
                     GIASHTWQSCSSAGSNIGFSAMINSAKVLACSAYDVFMNTKIIDEAKIEFDKSLDGQK
                     FKPLV"
     gene            complement(26429..27964)
                     /locus_tag="JAM15_09895"
     CDS             complement(26429..27964)
                     /locus_tag="JAM15_09895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798563.1"
                     /translation="MLNNLSNININENNLIKNQYSISLLKECLNCKVIDEREVYNIQQ
                     EISLILMDLIKKYTNGQSTSVKTEVAEKLLISIWYAIDAYINKLGDIEKRVVELTAKN
                     VKKVYLGGIEILEEELVRLKDFYKLMMSRKLDTNSIAYNDTLMELSSFFKSYIVKFEA
                     QDVPVSIDYPLALDDMDVKGIYYVKNYIESIDIENRFCNLFKKKDREKLFYDYGVIYK
                     IDCDVILVNLFELIINNCIFSTILGNEVTNLEISKYEYEFLEKQFKNMYNNITEDKVI
                     GSEESNIIELIEVDDSFNTEVDSNLDYNDFEEINREIRINKKITLLLMEAIEVLIKRL
                     SIEDEDVIRYIKKYEKIFIESVLSSIKSNTFKSMVTVSKNKNEHLEDYIVDDESKLDD
                     ESFREIFNEILDSTSIIEKIRIIKENINAKKDFIDILESECLFGEEYLMLFASLSELE
                     LAILGSVVFYEDIRMREINILEFMLNEKTETTLWKIEYIKFMKRQSEDKIYSIEEHMN
                     KIN"
     gene            complement(27987..28421)
                     /locus_tag="JAM15_09900"
     CDS             complement(27987..28421)
                     /locus_tag="JAM15_09900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798564.1"
                     /translation="MISPIILSSINQNLKEIERNELLETNIESGDYGLALSESDVKDI
                     INSRDNTLKGYGRIELDIKVTKQLIENIYTSQYTNVDNYLEAINDMQEIFYYLKNETD
                     DKICDDEIIEILGEFYEKFSGNMDNVRGEADEFAKKFKFGEV"
     gene            complement(28681..29592)
                     /locus_tag="JAM15_09905"
     CDS             complement(28681..29592)
                     /locus_tag="JAM15_09905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="HAT6798565.1"
                     /translation="MNKKIELIGNFASDWIRYSDYEYKITEEDELYIVPTEDAVFTMY
                     NPFDVADDIIVDIIRIGQEALQDISKETKEMKLKKEVLEFVKKYGLLGLIYSSVYNRD
                     IVGEERVQMIEKNYITKENILSTDEYVNMFIPFASDEDVYFKKYRRGIDVSKREESPK
                     FFGKRPLILDLVFSKFYTEQLDWIVSFAKDMCKHFNQICVYKNTSNLLTESVTIMSGG
                     FNPQKIGFSISQLDKPIIAWEFDSLKTAIETIYAFAITSEPSSLNKCKYCGKIYIPTN
                     SKSQYCSPSCRNCSNVKKSRSRAKKDK"
     gene            29888..30241
                     /locus_tag="JAM15_09910"
     CDS             29888..30241
                     /locus_tag="JAM15_09910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HAT6798566.1"
                     /translation="MDRKRELKQLYKEMKFDTGVFIIKNDITKKIYLGKSNDIKSKFN
                     SLKFQLGAGSCMIKELNNEWKKYGEKAFTFEVLELIKHDDNKTEKDYLEELDILEMIW
                     LEKLKEDNTYEIYSI"
     gene            complement(30470..31411)
                     /locus_tag="JAM15_09915"
     CDS             complement(30470..31411)
                     /locus_tag="JAM15_09915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp25"
                     /protein_id="HAT6798567.1"
                     /translation="MRISKKVLALGISALLLSVSFPTSINALDKIENIQGVDKYETAG
                     LISDKQDFTTAVLINADSTMVDGIAASGLAGVNNAAILLTNKDDIPEATLQRLNRVTK
                     IYVIGGENSISKDVEKMLLMRRMQVIRIDGVDRVDTSYKIAGEIEKIKNSDKMFLVNG
                     FKDEADAVSVASVAYRDGAPIILTKDIPSAEEDTDLDPWFGVSPVPVYAIGGESTLSD
                     YIVSRYRATRIGGVDRYQTNKNVIEKFYNGAKEFYITSGDDLVYALVASPLAKNAPVV
                     LVSNKSDKSILSGASKVTAVGISDKSIIEQCLDAVKK"
     gene            complement(31512..32747)
                     /locus_tag="JAM15_09920"
     CDS             complement(31512..32747)
                     /locus_tag="JAM15_09920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAT6798568.1"
                     /translation="MKILHIITQKPNSTGSGIYLSGMIKGFEKIGHKQAVIAGIDVND
                     DVNCFPSEVSFYPVKYNCGELNFPVVGMSDSMPYESTRYKDLNIDMINRLKYQFKVNI
                     DKAMNDFKPELIICHHLYLLTAFVREIVKDIKVMSICHGTCLRQLNTIDLEKEYIIAN
                     IRKLDLIFALHENQKYDIIKTFGVSESKVVVIGSGYNDDIFYNKNYKIKDDKIKIVFA
                     GKICKSKGLIPFIKSISKLKYSKDLIEVNFAGTGSDIESYNEIVKLASKSPFKMNFLG
                     KLEQRDLAELFNRSQIFVLPSFYEGLPVVVLEALSCGTDVITTDILGVKEWIGSEINN
                     SGKIEYISLPFMEKEGIPKDEELYDFENNLYNAIDSKIQSLLNNSNEKTSVDMSKKTW
                     DGLAYRINEVILMDELCLV"
     gene            complement(32791..33645)
                     /locus_tag="JAM15_09925"
     CDS             complement(32791..33645)
                     /locus_tag="JAM15_09925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798569.1"
                     /translation="MALNIRNYSLLCNQGTAKFNEDVVGINPFGAWVLDGATGLNGKN
                     LVSTESDARWYVQWWNRYLYKNINKEESLKSIINTGIIEVKKEYELRLNGFKVEKLDL
                     PSSSIVVVKFHENKVEYFLLGDCALFIKNGDSKVIKDRSICKFDNTVFDEMSKLSNLE
                     EMAFDEIRTSVMDTIVSNRLKKNTKEGYWILDFDEEAVENSIYGYIEIKKDFQLMLTS
                     DGFTSACDRYNLIKEEELIRIAEKFGIGYIHNKVRDFEDNDYKAVKVPRFKIKDDSSC
                     LYLDIYND"
     gene            complement(33773..34948)
                     /locus_tag="JAM15_09930"
     CDS             complement(33773..34948)
                     /locus_tag="JAM15_09930"
                     /EC_number="2.1.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008776581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolecarboxamide
                     formyltransferase"
                     /protein_id="HAT6798570.1"
                     /translation="MARELELKYGCNPNQKPSKIYMKNGELPIEVLNGKPGYINFLDA
                     FNSWQLVKELKEATGLPAATSFKHVSPAGAAVGVPLSDTLKQIYFVDDLELSPLACAY
                     AMARGADRMSSYGDFIALSDVCDKETATIIAREVSDGIIAPGYTDEALEILKGKRKGN
                     YNIVKIDENYTPEPIETKDVYGITFEQGRNEILINEDLLKDIPTDNKIFTDSAKRDLI
                     IALITLKYTQSNSVCYAKDGQVIGVGAGQQSRIHCTRLAGNKADTWYLRQHPKVLNLK
                     FKKDIGRPDRDNTIDVYLSDDYMDVLADGIWQNFFEEKPEPLTGEGKRAWLKTLTGVA
                     LGSDAFFPFGDNIERAKRSGVSFVAQPGGSIRDDNVILTCNKYNIVMAFTKNRLFHH"
     gene            complement(35047..35931)
                     /locus_tag="JAM15_09935"
     CDS             complement(35047..35931)
                     /locus_tag="JAM15_09935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HAT6798571.1"
                     /translation="MKFVTFCSSNEEKIGVFNSETNSIYEINSLGLSKLYTDMNDFIE
                     NVSTGDLEKIKNNSFENAKCYKLEEVKLCSPIVRPKKDIICLGLNYKDHVNEIPDGVI
                     KNVVMPDYPIYFSKRADKIIGVDDKISLHGDLVEKLDYESELAVIIGKEGINISKEDA
                     YEYIFGYTIVNDISERALQDKHVQWFRGKSLDTHTSMGPCIVHKEEFEHPLKLDISSV
                     VNGEVRQNSNTEYFIFDIPTIINDLSRGMTLKPGDIISTGTPAGVAMGMNPQVYLKHG
                     DIVECKVEGIGVLKNIVD"
BASE COUNT        11730 a         6278 c         3860 g        14132 t
ORIGIN      
        1 ctgggtataa atataggttc tataaaaata ctaggactta tgatttcaaa tggacttata
       61 gctttatctg gtagtcttat ggctcagttc ttaggattct cagatgtaaa tatgggtata
      121 ggaactttag ttcttggaat tgcctctatc ataattggta ttacactatt taagaaattt
      181 acttttatca aagatactac tgcaataatt gttggctctt ttatatacca attcactata
      241 tactttgcaa tgagtttagg aatgttatca actgacttaa aactaataac tgccatagtt
      301 ataatagctt tcctagctac tggtaactta aatatttcac taaaaaaaaa caaatgcaaa
      361 gctagtacca aaaataaatc agaaaaaaga ggtgttgtag atgttacaaa ttaaaaatct
      421 ttcaaagagt ttccctaatc catatggtga acctaatact atctttgaaa atttatcaat
      481 cgatatagaa gatggtgaat ttgtaagtat cataggtagt aatggaactg gtaaatctac
      541 tttattaaat ataatatccg ggcttataaa agaatcttct ggtcaagtat tattaaataa
      601 acataacttg tctaatttag ctgaacacag aagaactcaa atagtaagta gagtttttca
      661 agacccaagt cttggaactt gcccttctat gactgttaga gaaaacttgt ctttagctct
      721 taacaaagga aaactattaa atctaagaaa atgtcttcgt tacaaaagag atttcttaga
      781 aaatttattg gaaggtgtat ctcttgattt aaaaaaatac cttgatgttc aagtaaaatt
      841 tttatcagga ggtcaaagac aatcattatc actaattatg tcgtgcttaa caagtccatc
      901 agttttatta cttgatgaac atacagcagc acttgaccca aaaacatcaa atgaagtaat
      961 tgaattgact aataagattg taaggggaaa aaatataact acacttatgg ttactcacaa
     1021 cttaaaacac gctcttcaat atggtgatag attgataatg cttcataagg gtgaagttgt
     1081 cttggatgta aaaggtaaag aaaaagaaca attaacagtt gaagaaatct tagaaaaatt
     1141 tgaatatgca gtttaaaata atatatctat tgtattaaac tcagctttaa aataaagtta
     1201 aaattacaat aattatggtt actttataat aattcatatg aatatatgaa catatataat
     1261 aataaatttt tgagggggat ataaaaatga ttaataaaaa aagattggca agtttgattt
     1321 tagctggtgc tcttagtata tctatgctta caggttgttc acaaggagga gactctggta
     1381 attcaaaaca agaaagtaat tctaaaggta aagaagttaa aaaaattggt ataactcaac
     1441 tggttgaaca tccagcatta gatgccacta ggacaggttt tgtaaaagca ttagaaaaga
     1501 acggatttaa agatggagaa aatattgata tagacttcca aaatgctcaa aatgacatgc
     1561 ctactacaca aagtattgcg agtaaatttg catctgataa gaaggactta atatttgcta
     1621 tatctactcc atcagctcag gcagcattta atgctactaa agatatacct atacttatta
     1681 ctgctgtgag tgaccctgtt gctgctggat tagttaaaac tcttgaaaag ccaggcacaa
     1741 atgtatctgg aacatcagat tttgtttctg tagacaaagg tttagaactt cttaaaatat
     1801 ttgctcctaa ggcaaaaact ataggagtta tgtacaatac tagtgaagta aattccaaag
     1861 ttcaagttga tgctttaaaa gaatatgcat ctaaaaatgg atttaaagtt gttgaaaaag
     1921 gtataactac ttcaaatgaa gttaaccaag gtatttctag tttagttggc aaaatagacg
     1981 tattatatgt tcctacagat aacttagtgg cttcttctat gcctatagtc tctaaaatag
     2041 ctactgagaa taaaatacct gttatagcag ctgaatctgg gccagttgaa aaaggtgctc
     2101 ttgcttgtca aggtatcaac tacgaaaaac taggttacaa aacaggtgaa atggcagtta
     2161 aaattttaaa tggcgaatca gtatctgata tgcctgtggc tacatcagat gatacagata
     2221 tcattgttaa tgaagatata ttaaaagctt taggtatgga aaaaccttct aatgaaaata
     2281 tttcttatgt aaagactaaa caagaataga aagatatttt ctatatacga ttaatatgcc
     2341 tgtttctata aattaattta tagaaacagg catatatttt tattttaatg tattatctat
     2401 ttaaagatta tatgtaaatg ctcttaatat gattgtataa attttacttg tataaacttt
     2461 atacaatcat atttattctt ctattttctt tattactcta catggatttc caacagctac
     2521 agtatttggt ggtatatctt ttgtgactac acttcctgca cctattacta cattatcacc
     2581 tatagtaatt cctggtgtta tgattactcc cccacctatc catacattat cacctatttt
     2641 tacaggagaa ccatactcta tgcctgaatt tctaagttgt gcatcaattg gatgataggc
     2701 tgtatagatt tgaacgtttg gagctaacat tacattgtca cctatttcaa ttttacatac
     2761 atctaaaaaa atacaatcat aatttgcaaa gaaattttcg cctacatgta tgttatatcc
     2821 ataatcacac ctaatgtttt gttctacatt tatttgcttg ccaactgaac caaatagttg
     2881 tcttaaaata tcttctcttt tttcatattc atcctctaaa gtattattaa acaatctagt
     2941 taatttttta caatactctc tttcttttac taacaattca tcatttgcat agtatccttt
     3001 cccagacaac attttttctt tttcagtcat atagtttact cctttttgtt ataattgtat
     3061 ctaaagcaaa ataaatattc ctgtggaaaa tctaaatata ttctgtcacc tttcttaaat
     3121 ctcattttac ttttttccaa ttctatttga ataggtacac attcgttaga taaatcagtt
     3181 tttctaacat atatagtata tataaaagga ttttctacaa tgttaatcaa ttcgaaacat
     3241 aacttttcat ttaaatcttc attagaatcc aagaccttaa tatgatgctc cctgattccc
     3301 acatattcta tattatcacc tatttctcta tttaatgtca actcgcatcc ccagtctgta
     3361 gcataaatag tatttttatc cagtctattt aatttggata tatttttaca ccctgttatc
     3421 ttagcttcta taaggtactt tggagattca aagagctctt ttttaggtct ctttggaaga
     3481 ccttctcctt tgttgtacac tataatatca tcacaaactc ggtaagcttc ttcaatatca
     3541 tgagtaacaa atagtatatc tcccttgtaa tcttttaaca tattcataag ttctttttcc
     3601 atattacttc ttaaatgatg gtccagtgct gagaaaggtt catctaaaag taatatatct
     3661 ggagatgttg ccaatgctct agctagtgct accctttgtt gttgaccacc agataattgc
     3721 caaggatatc tcccttcaaa cccatttaat ttaagtatat ctaagtacct tgctactatt
     3781 tccttttttt cactcttact tagttttaaa agcccaagtt ctatattttg acttacagtc
     3841 atatgtggaa acaaagcata gttttgaaat aaaaatccta cctttctatc ttgtgttgat
     3901 aaatttatct tcttttcaga atcaaataga actctatcat ttaatacaat tttacctctt
     3961 gttggtttct caagccctgc tatacatttt aatgtcatac tttttccaga accagattcc
     4021 cccaaaaacc ccagagtacc tttttcttgt ttaatttcta cctttagttt aaaagaggat
     4081 aaatcttttt caatatccac gtataagctc aactatccac acctctttcc tataattttt
     4141 tgctgaaatt ccgaccaata atttagtaat aaaatcattg ctatagatat tgctacaata
     4201 atcataaccc acatcatagc tttattcata tctccgcctt caacagcaaa aaatatagct
     4261 attggcatag tttgagtttt tccaggtata tttccagcta tcataagtgt agcaccaaat
     4321 tcgccaagag ctctggcaaa cgacagcacc aatccaccaa ttattccagg ccatgctaat
     4381 ggaactgcaa tcttaaaaaa tactttccat tcattaagac ctaatgttct agcagctgac
     4441 agcatattat tatcaatctg ttcaaaagct gaccttgaag ttctatacat cataggaaaa
     4501 gacaccacta ctgctgaaat tacagttgct gtccaactaa atattaaagt cctatcgaaa
     4561 tttaataaaa actttcctat aaatccattc ttcccacata gtaataataa aaagaaacct
     4621 acaactgttg gtggcaaaat tagtggaagt gtaaatagtc catctataag acccttccac
     4681 ttacctctat agttagccat aatatatgac acaaatattc ctattacaaa agttattatt
     4741 gttgacaaaa tagatgtctt aagtgatatc cataagggtg accaatctgt tcccatcttt
     4801 ccctccttaa ttttaaatgg aaatagtgaa actaataact ctattaattt cactatttcc
     4861 attttattat aatacacaat tattttcaat tttcatttgt ttatatataa tttatactta
     4921 attacacata atttatttat aagtttattc tactttttta tatccaaatt cttcaaaaat
     4981 cttttgtcct gactcactta ataaaaattc ttcaaatttc ttagcagcat ctacgttttt
     5041 actagcttta attactgaaa ctggatatgt aataggtgaa tgagtttttt cgtctgtttt
     5101 ttcaactact tttatcttat cattattgac agtatcactg aagtaaacga atccaacatc
     5161 agcatttcct gattgcaccc atgctaaaac ttcttttaca tcttttgcaa atactagctt
     5221 atcttttaac ttatctttta aatttaaatt agttaacacc tcatctgcat acttaccagc
     5281 tggaacactt tcagcttcac caacagcaat tttcttcact ttatctgtag tcaaatcttt
     5341 catacctgat acactactgt cagcagaaga aataagaact aaatcatttt ttactaaatc
     5401 tttcatagta tcagaaacta ataacttctc ttcatccaaa gctttcattt gtttttgacc
     5461 tgctgaaata aataaatcac aaggtgctcc ttgttctatt tgttgttgta atgagcctga
     5521 tgctccatag ttaactgtaa gttttacatt tgaatcaact tttttatatt cttcttcaat
     5581 ctctgccatt gcttctttta aacttgcagc agccgatata tttaactcta ctgaatcact
     5641 acttttagtt gttttttctt gttttccatc atctttttta tcttcattac tattgcaccc
     5701 aactgtcccc aaagttaaac atgcaactaa tcctaatatt cccaatattt ttttcataac
     5761 aatctccctt tttgtaaatt tgatacacat tttaatatgt tttattatgt tttatcatgt
     5821 tttgttatat atagtttaat tatatataca tgataataaa ttttcaagta atttatttac
     5881 actactttta aatattttgc tacattttcc tttttttaat gttaaaataa ccttatatgg
     5941 aggtggatta tggactcatt atcatctttg acacctgtcg aggtagctga attattgaag
     6001 ataacaaaaa atactgtata tgaattaatc aaaagaggtg aacttccttc ttataaagta
     6061 gggaaaaaaa taagagttga tactaaagat gttgaagaat atatcaacag ccaaaaaact
     6121 ggtaaagtaa aggatacaca tttcaacaat aaaaatatag atataaataa taatttcaaa
     6181 attattattt ctggtcaaga tgtaatatta gacattttag ctaggtctgt tgaaaaaaaa
     6241 ttggatggaa taagtacatt tcgctcttat ataggtagtt ataatgcttt gtatgagtta
     6301 tataatggca gagtttctat agcatcatcc catctatggg atttcgaaac ggatgaatat
     6361 aatagcactt ttgttaaaaa gctattgcca ggaataccat gtgtacttat aaatctagct
     6421 tatagaatgc aaggtttcta tgttgctaaa ggaaatccta aagagataac aacctgggag
     6481 gatttaacaa aaccaagtat aaccattgta aatagggaaa aaggttctgg aactagggtt
     6541 ttactagatg gtaaacttag acttctaaac tttaatggta aacatataaa aggttatgat
     6601 aatgaagaat tatcacatct tggagttgca agtactgttt ctcgtggaat agctgatgtt
     6661 ggtttgggaa atgaaaaagc tgctttacaa gtaaataata tcgactttat tcctcttcac
     6721 aaagagcgct atgatttagt tattaaaaaa gaagacttac aaaatccagt ttaccaaact
     6781 ataattaaca taataaactc tcctgagttt aaagctgaac ttcaaggtct tggcggatat
     6841 gatttaactg atactggaaa aactatagca aaagtttaag attaaaatcg caatctattt
     6901 tataagattt ataatttttc acaaaattta taacttaaac acgaaataaa ttgcgatttt
     6961 agtgtctcaa aaaatttatg tctttcattt tatcatccaa tacaaaatat aatataatta
     7021 attgtgcaat catattatat taatatatat ttacataata gtatttttct ttaatgtaga
     7081 ttaacatatg atatgtttta aacatcaaca cccttgcttt cttatatata tgtggcaaca
     7141 catatgagtt taataaatta tatacaatgt tgctttcttc ttgtattttt tcaaccaaca
     7201 agttatttat aaaattacct ttctcatttt caataatctc actccaattt atcttaactt
     7261 ttaatatata tcttcccact aggtatacac actctacaat aaataataaa aatacaatgc
     7321 agtcagtacc tgttgtctta tataaattac ccgatactaa tggctttgcg aagaaattat
     7381 aaaaattcaa agtatcaccc gtataatcaa aaagtattaa tagcactcct agaactctca
     7441 atactttaat attcaacatg tttttatctt tattattttt gtttttcata tatactacct
     7501 ctcttttctt tagatttgat tgtaatctaa tactaactct tttatttgag gtataaatga
     7561 atttaattgg tagttatttt catttttact agaaattaat tcacattact aaacaaaact
     7621 tatatttaaa cataaaaata gcctatctat tttttaataa atacaaaaat aaataagcta
     7681 ctaatattca attaactttt atcacttaaa acattactat ctataaattt aaatatttta
     7741 ttgaagtata ctgtactatc atgttcaaat ccatcaacat gaccaatacc ttctataagc
     7801 cataggtctt ttttatcatg tttaactaaa tcatacattt tcttgctatt ttgataatta
     7861 caaacagtat cttttgttcc atgtataaac agtatgggta cattagattt ctcaactgac
     7921 tcatatggtt ttacatcact gtaccaaaat ccagatttaa acttattata taaatctcca
     7981 caaatcacca cataattgat taatatatct ggtatttgtt tttctagtac tcccattcta
     8041 attgcatctt tcatttcaga ataaggagaa tccagtatat aaaaatcgac cttatcatct
     8101 tttgaattta tctctgaatg catagcagct gtccctgctc ccatggaaaa tccatgcact
     8161 cctaatcttc cttcaggaaa tttatttttt acaaatttaa ctagactatc taaatcatac
     8221 ctttcataaa gaccaaatgt gtaattatct ccaccactat taccagtatt tctttgatta
     8281 taaactaata cattataacc tttatctaaa tatctatatg ctacctttaa catttcatag
     8341 taactacttc caattccatg aacaagtatc atagtatctc ttgtctttat atttgaagtt
     8401 ataaaaagac tttcaagctt gtaattatta gaactttgta tcattaattc agatgtcttg
     8461 tagtttttta atttctccag tggtttatct tttctctcag aaaatatttt tactatatct
     8521 tcgtttttta ttaactgctc taaaccaacc gaactattat acactaattt gccaaatata
     8581 taagatacaa ttaataggat taatagaaac acaattgata taattataaa tttatttctt
     8641 aaactaatac aatttttaaa actatttttc atatttattt accatacaat tttcctatat
     8701 tatattttct aagtaatagc ataattgatt atactattct tataatttct attataccta
     8761 cttatttatt aaaaatacaa attatatttt attaattttt actacttgta aattattatc
     8821 ttatacaatg aatttgtatt atataataag tatttttagg attctgttac ataatattat
     8881 ttaaatattc ttctatattt ctcttcttct tcttcagtaa acacattaaa tacaactttt
     8941 aaattttttt caggattttc ttttagccat agtctaactc tacttacagc aagattagct
     9001 gcctcttttt ttggataacc aaatacacct gtagaaattc cacaaaaaac aatatttttt
     9061 atttcatcaa tttcttttat tgtatttaaa catgatttat aacaatgaag cagttgcttt
     9121 tcttgctctt tacttggctg accaccagat acaataggtc caacagtatg tactacaaat
     9181 tttgcaggta aacaatagcc tctagttatc ttagcatctc cagtatattc taaatgccct
     9241 tgttttttta ttattttgtc acaatcttct ctaagtctag gacctgcgca tgaatgtatc
     9301 tcattatcca cgcatagatg taatggttgt aaacacccta ataacttgtt atttgcagca
     9361 tttactattg catctgctct taaattcgtt atattacctc tccatatggc aatcccttcc
     9421 tctacttctt ctatatcatt tacatctact aactctcttt cttcacattc aatcaacaat
     9481 aaattatgta acatattaag tatctctgga gcaatttctt ttggtggata tacattcaaa
     9541 agtcctctaa gtatatctct aggcttaatt tcatcatttg ataaattgta tattttagaa
     9601 ggaacttctt ttgaaaaata tgcaattaaa gtgtttatat tttttcttct ttgttcgtca
     9661 gttagaggct tgatagtttt atcaaaatcc tcaaataaat ttacatcatc agcataatct
     9721 ctccacttca tagccatctc tccattcttg tattttagac ttaaaaataa ttatgtattt
     9781 atgtacatat ttatttattt ctataaacac ctacataaat cctgttaaaa gtgtaaattt
     9841 tttattatgc aacttctctg gttatttcta ttgattgata gtaaattatt gtacctaaat
     9901 ttaatccaac taacaagtaa ctaaacctac tttcctaact gcaaaataca ctatgtttgc
     9961 cacttgtatc tcatttgtaa ataaataaag tccctacaaa tacattaact aggctatgta
    10021 ctaaactgta ggaactttaa aaatatatta ttcttaatta agttttggcc aataattttt
    10081 atttgcttct attaaatcat ctagtaattc ttttgcaact gttgcactag gaactgtctt
    10141 agatagcata agtgcttgcc acaatttatt ataagacttc tcaatccaag catcaactac
    10201 taatttttca actgctaatt gttgttctat taaacctttt tggaatgttg gtattttccc
    10261 tattgataat ggttcatacc cgtcttttcc aactatacat ggaatttcaa ccatagcatc
    10321 atcttgtata ttttctatag ctccattatt ttgaactatc aataacatac gctcctgtgt
    10381 attaaaagct agagctgtag ctaaatccac tataaactct gcatgtattc ctatcttaag
    10441 cccactgccc ttagaatgtc cttgcttttc tatcaatgca catgaaccaa aaacttcttt
    10501 ttctcttcca tcaataactt cattggcacg agtataattt acatcagaat gatttacaac
    10561 ataatctgga aatagatagt actttaagta actacttggt attgtagtta aatctgtttt
    10621 tactatttct ttagtaaata aattagtttc aaaccaacta tctttcttgt catttttcat
    10681 tccttcttca ccatttataa aaccatattc ttttatatgt tctactaatt ttggtaaaag
    10741 ttcatttcct tttttatctt taattgaagt ataccaacca aagtgattta atccaaagta
    10801 tcttatatcc atatgtttac gagatttgag tcctgcaatc cttgctatat tatgttccat
    10861 acctattggc atatcacaaa tatttattac cctagaatta ggtctcaacc ttctaacagc
    10921 ttccgctatt attgatgctg gattagaata atttaacatc caacaatttg gagaatactt
    10981 ttccatataa tctatgtttt caagaacacc ttctatagac ctcattccat aagctattcc
    11041 acctggtcca caagtttctt gaccaactac tccatgtttt agaggtatct tttcatctag
    11101 ttctctcatt tcaagttttc caactcttat atgagctaaa caaaaatcta catctgtata
    11161 agcctcttta gggcatgttg ttgctaaata ctctatatta gggtcctttt cctttattag
    11221 tatttcacaa gctttagcta ccttattttg tctttcttca tcattatcat ataatttgat
    11281 tgctcttaat ggtaacctat ctaagttatc tagcaacatt aatatgattt ctggggtata
    11341 tgtacttcct cctccagcta ttactactga aaatttttcc ataataatat ctccttttct
    11401 atttaaaaat ttactgtatt tataaataaa tttataaata ctagtacttt aaagtaaaag
    11461 ggagttcatt tattaaatct attgatttaa taaactatag ccaaacttca agcactattt
    11521 acaagaaatt taattcttat taattcttgg gtccatcatc tcaaatatat ctacaagttc
    11581 agatactaaa gaatgagcaa ataatgcatt tgaataatgg tcttcagagt gcacaactaa
    11641 aaaatcagtc ccactatctt cactattcat agcatttgat agtaattcta aatgatgctt
    11701 tgatgctgtt tgtattttct ctgaggctga atttaaaagg tgttttgctt tattgtagtc
    11761 accttttttt atttccttaa gagacatcat tacatcactt ttagcatctc ctgcttctga
    11821 tattatacta aatacttttt cttccatttc aggtaccata tccttctcct tctaatgact
    11881 tgttaaaaat caaagctatc atcatctaat gttgtagcta attctgcatt tttatttaat
    11941 tcttccttct ccattatctt aaagaatgga taatatatca aggtcataag tattatactt
    12001 gcaaatacta atacgattgc cttccaatct aatgtcatca aaaatgctgc aacccctgga
    12061 ggtaaaaagc ctggtggttc tgcaataggt aatcctacta atcctacttt taatgccata
    12121 aaattaagtg ctccaaccaa tacaggtcca aatacaaatg gtacaaacat atatgggttc
    12181 ataactattg gtgttccaaa tattactggc tcatttattc caaatagtga tggtaaaatc
    12241 acaacttttc ccatactatt aaaactctta cacttacttc ttgacataag gtacactaat
    12301 cccaaagtta tccctgaacc agttacttgc aagaaaccat agtaaaatcc tattgtaaac
    12361 acatattttg ggtctcctcc tgctgctatc agtgttgcat tttctgccat atatgtagct
    12421 gctattggca tccatatact tgaagttatt gctgctccat gaaggccaaa gaaccataat
    12481 aattgagtta taaatagtat tatagttact gcaaaaacat tatctacact gcttatagct
    12541 ggtgctaaga aattcattat aatagctggt aatggttgac ctgagacatt tttagttatt
    12601 gctgctattg ctgtaaataa cattatacat actatcattg gagttaaatt tctaaaactt
    12661 ttatttacta cactaggtac ttcttttgga aatctaatta cgagattttt atcattcata
    12721 aacttagtaa tatcaactac taaaagtgct actaatatac ttacaaataa accttgtgca
    12781 tctaaataac ttgtatctaa tacaccatct actacttgtc cacatacaac aagttgtgca
    12841 acaactgctg tcatacctat ttctacatga ttaagattat attttttagc tagtgcctga
    12901 gctataaaaa atgctgaata tatagataat aaactcatag taaatttatt agggataagt
    12961 aatgtatcca tattttcaga taataatgtt tttgcacttc cttcaggtaa catattgttt
    13021 aatgccataa ataacatact taaagaacca acaattatta ttggggtaat gcttatcata
    13081 ccttctttta tagcttgaag atgcctttgt ttttcaatct tttgtgctat tggtagaaga
    13141 aatcttctta aattattttg aagtgcttcc atttttattc cccccaatta tctattttta
    13201 tataattcga ttgccgactt cataacagaa ggagcatcca tacgaccata atgcttagta
    13261 tctattaaac caactgctat tttgtaattc ttacaagctt caactacatc atcttccttg
    13321 aacctaattt gtggtgctac aagtactaca tctgtatcat tagcttcaat gtatgatttt
    13381 aaattttcga atgatgttgc ctctatattt atagttttag tttttaactt ttcatgctca
    13441 ctacaaaaac ttttcatctt ttccacaagt acacctgttg aagctccatt tgcacatact
    13501 aataaaatat tcataattac cctcctacaa tatctaacct cttttatttt ctaatttttt
    13561 atcagccaat tcttactcta attcctatca gtttttactt taattcttat tattttattt
    13621 taattcttat taatatttac tctaattctt agtactgcca atgattaaac ttgaaagccg
    13681 tatctataac ttcttcttgc ttatattttt ctaatatttt taagtatctt tctttataat
    13741 cattatctac ttctttttct ggtattacta tactagcttc atttaaaaag tggaatgaat
    13801 cccttcccat ttctaatcct ctatatgtat gcttgtcaag tgccacgtcc ataacttctg
    13861 gaactttacc cattgcaaat ccttttataa ttatattttt taataaatca cttgatctat
    13921 ctttctcaca tgcacaaaga tatcttattg catgtatgaa aaataaaggt ctgtctccat
    13981 ctgcatatga atattccttt cttacttgat ttaaattatt tatgattatt acagctgatg
    14041 ggtcccccat tcctatatct tcaactgata ttgtaagtat ccttctccat agcttatctt
    14101 ctaattctgg tgatgatata tatagttcat aagcaaattc acaagcttct tccaccatat
    14161 ttcttcttat agctttttga aatgacgata ttatttcgtc tgcactaaat ccgtttcttg
    14221 tagtcattct tgcccatggg tcatttgcct ttttatctct taatatttta tcttgcatat
    14281 tatttactcc tttttattta aattttaatt atttatatta ctcatttaat aatataagca
    14341 agtattatgc cagttttttt agacacttta aaacactgtt atttcaatca tttttatcat
    14401 caaaacttag atactttgtc taagtatatt tatatgtgtc taatattaat attattttag
    14461 actaaaaaaa attaccaaat aagtttttat actcattggt aatctttttc gattatttct
    14521 gcatattcta atattaataa tatttgatag cactcttttt cattaatttc tatattatat
    14581 tttttatcta attgagatac tatatctttt attttgctta ggctcttgtg ataatcaagt
    14641 gttttttctt tatcaagctt ttcaatttct ctagtatttc caatcaaccc atctaccatg
    14701 aaagctaaat gcatcataag tccaattact ttatcgtatt tcttttctat attaaatact
    14761 aaaaacaatt catcagacac atattttata tctttaaata tcctattata attagagctt
    14821 tttaaggatg tctttaaacc ttcaactaca tcatcataac ctatacttat ctttataata
    14881 ttttttaatt tattgatatt ttcatcctta tctatatctt ttttgctaat atagtcaatt
    14941 cctctaatat taattctttg ttcattgatt actgcaacaa tattactact ttctttaagt
    15001 tttgtaatat ttaaacttaa atctttttct gttttatatg ggacagatat aatatctatt
    15061 ccatctaagt acctactcat cttttcttct aatatttttc ttgttttatt atctacacct
    15121 tctgaaacat gtgatgctat aataattgtt ttagacagat tttctttatt ttgaatttca
    15181 ttagttccaa aataatactt tctcgtgtta gtgatagagt tgtatacgtc atttaaaggt
    15241 aatcccatat tggccttctg aactgcttct aacacagtta atgtcgtcac cataggaatt
    15301 actcttactt cacacttttt ttctttcttt ataatttcat caaaggagtt taatgaaccc
    15361 atatctgtaa atagtaatac atctttattg tctatattat taattaaatt tttaaaatct
    15421 acaataactt catcatagct tttatctaac ttcatatcga aagaaatagc actgcacttt
    15481 ccaataatat caccaactgc ttttaccata ctacttgctg tagtttctcc atgcatagca
    15541 actataatat taatgttatt cactatttta ttttgttcat cttgtttagc ttgtactatg
    15601 aataatgtaa tatatgctac agtttctata gataaaaata aatcaaattc attttcaatt
    15661 attccaacta tttttagtgc tgttttaaat tcacttctgt tatttcttct aatttgattc
    15721 aaatctatgt tgtttgtaga gctactttta tccaatacgc tttttatata aattgccatt
    15781 gacttaaata ttgattcact tatatctatt tcttcatctt ctttaataat ttgtcttatt
    15841 gattcacaca tgcttttaaa cttaacatta ttaaatagag aagcatctgc tatattcatt
    15901 tctacagatt tattaagatt agtatttact gcattaataa tatttatatc attgtagtta
    15961 ataacttctt cttctcctaa tgacgtaaat acaaaatatt ctattccatg tgttataact
    16021 tcatctgctt taatagactt ctctctataa tcatcactca cttcatttat agatttatca
    16081 aaatattttt tctctatata aactggttct ttattatctc ttttatatct taggtatcca
    16141 tttgcaacag ctaattttat atcattttga agttgaccta cattattttt acaatcataa
    16201 agtaatagtg atttaattat ttctttatgt acttttattg aaatagaaat actttttgat
    16261 tcttccttga aaaaattttt gactaattcc attctttcaa tcattgtcct atctctcagt
    16321 gatggtattt ctattttcat tggtattctt ctattgaatg tatctaatag tgttgatgtc
    16381 ggattttctg tagtagcaca tattattaat accttagaat ctctttcttt cgttgcatct
    16441 cctagtcttt taaatgttcc cttatctata aaagtaaaca acatttcttg accttctgct
    16501 ggtagtctat gaatttcatc taaaaatagt atccctccat ttgcaatttc caaaagacct
    16561 tttctggaag attctgcacc tgtataagct ccttgttcta ctccaaaaat atgtcccata
    16621 agtaattgtg cattattagc ataatcagca caattaaatg ttacaaaagg agctttattt
    16681 tttctaattc cactatctat agaataatcg tacatatatc tagcaatcat actctttcct
    16741 actcctgttt ctccatagat aatagtatga agtccatttg taggatagag cattgcgacc
    16801 ttgcattttt ctattatagg tcttaaacta tgttctttac ctattagtgt ttcaaaacta
    16861 tcttttttta ttttgttttc tacttttgtt ccttttttta tgccaagcaa ctcactttgt
    16921 gtatcaagca attcattctt gttaaggtta agatttgcag ggatataata cacaggtctt
    16981 ccttttatct tcgtaaccat accctcattg aataattggt ttaaatatgt acttatattg
    17041 tttcttgcaa ttcctgtctt ttctgataat tggttagctg taatcccttt ttcattttcc
    17101 ctatatgatg attctaaaac tttcattact ttatcttttt tatatatcat tacaagctcc
    17161 cctacattat aatattttat taactaaaac ccctatacac actttatttt ttaataaact
    17221 cttattcttt aactaaggtt ataatttatc aaactttcct tactttaaat tatagaaaat
    17281 tattgtagaa aaaataagat tattgctcat tttttctaca ttactatttt taattttata
    17341 gtactttctt aacaacatac tttacttgtt tttaatttta ttatatttga atttattata
    17401 tttgaaaagt aaaaataaaa aaccctattt tggagtagtt ttaaaatttc tccaaaaata
    17461 gggttttagt ttgtatttca aataaatacc tgttcaagta tttttatact aaacaacttt
    17521 taaattttgt tgatatttat ttatttctga tttagaagaa tatacaaaat gtccatctga
    17581 aacctcaatc caacttaatg acttttcatt tgaacaatca tatccattag aattatactc
    17641 tattctattt cttgacttag catatctagg gtcaggaaca ggaattgcag aaagtagtga
    17701 ttttgtatat ggatgaatag gattattata caattcattt gaatctgcca attctactaa
    17761 ttttccatta tacataactc ctatacggtc actaatatgt ctcaccatag ataaatcatg
    17821 agctataaat aaacaagtta aattcttttc ttgttgcaat tttttaaata aatttactat
    17881 ttgtgcttgt atagacacat ccaaagaagc tataggctca tcagctatta taaattctgg
    17941 gtctactgaa agagctcgtg ctatgccaat acgctgtctt tgtccacctg aaaaatcaga
    18001 tggatactta tttgcataac ttctatcaag tcctactagc tttagcatct catatacttt
    18061 attcattcta tctgttttat ttttacagat accttgaatt tttagtggct ctgaaattat
    18121 atctgcaatt gtcatacgtg gatttaatga tgaagtagaa tcttgaaaaa taatctgcat
    18181 acttttgttt acatcttttt ttataaattt gtacgttttt ttatctgata tgcaatttcc
    18241 tttgtaaatt acttctccac cagtagattc atgtagtctt attatagttt taccagttgt
    18301 agattttcct gaacccgact ctcctaccaa tccaaatatc tcacccttat atatatcaaa
    18361 acttatatca tcaactgctt ttacagtagt acttttgtcc aaatgaaaat attgctttaa
    18421 gttttttatt tccagtattt tttctctatt cattagaaat cacccttcca caatttactc
    18481 taactggtac atctacttca ggtgcatctg ggtgcaataa ccaagttgct gcactatgtg
    18541 tatcattaat tttaaacatt ggtggctctt tttcataatc tatcttaagt gcatttttat
    18601 ttcttattgc aaaagcatct ccttttggtg ggttcaataa atttggaggc attccaggta
    18661 tattatataa atattcatcc tgtgaatcta aagtaggtaa tgaacccaac aacccccaag
    18721 tatatggatg tctagggtca taaaatatat cctctacagt tcctatttct acaatctttc
    18781 ctgcatacat aactgctatt ctatcagcta tagttgcaac tactcctaaa tcatgagtta
    18841 taaatattat tgacaaacct attttatgtt gtaaatcctt tattaaatca attatttgag
    18901 cttgtatagt tacatctaaa gcagttgtag gttcatcagc aatcaataca tctggattac
    18961 aggcaagtgc tatagctatt actatacgtt gtctcattcc acctgaaaaa tgatgtggaa
    19021 attgtttaaa tcttttctca ggattatcaa ttccaaccaa ttcaataagc tctatggctc
    19081 tcttttttgc ttcactttta cttatacctt gatgaatgat tacagcttct gcaatttgct
    19141 ttcctattga tatagttgga ttgagagatg tcatagggtc ttgaaatatc attgatatat
    19201 tctttcctct tatatcttcc atctcttttt cagacttctt aaccaaatca cttgatttaa
    19261 gtaaaacctc tccattttta atatatccat tgtatgggag tatcctcatc aaactcttac
    19321 acagtacaga tttcccacaa ccagattctc caactatagc caatgtctca ccttttttta
    19381 gattaaaaga tacatttctt acagcctgaa cttctccttc ttctacttta aaacttacag
    19441 atagattatt aacctccaat aaatgttcca aaaaccatca acccctatgc tattcaaacc
    19501 ttagggatat atttttatcc ctaaggtttc taattaattt cagtattatt caattgtcca
    19561 gtcagctatg ttccagaata tacctacacc atgatgacct aaaactgtat caggtgttaa
    19621 tccttttatg tttggttttc caacatatat tgcatctata taagcaataa atgtataagg
    19681 catatcctta gtcatttcta cttggaattg tttatataac tttaattttt catctttatc
    19741 ttctgtttct cttgcttttt gaagtatttt atctatagta ggattagagt aagcactgta
    19801 atttgcacct ttatctgttc caaatacttt atatgtatgg tcatctgggt caaatggact
    19861 tccccaacct attaaatgag catcttgatt agcccaatct gtttcagtta caacaacagc
    19921 tttagcatca acaccaattt cttttaactg ttgtgcacat attttagcca tatcaactct
    19981 aacttggtca ctctcacctg ctgttatctc gaaagctaac ttagtacctt ctttttcata
    20041 gattccatca gaacctaatt tccaacctag cttttcaatt tcttgtttag ctttttctgg
    20101 attatattca aacttttcta tatcaggatt attatatggt cccatttgta aaggtgaata
    20161 tgctggtaca ccatgtccta ataatacact gtcaactatt gcttttctat ctattgcata
    20221 gcttaaagca tttggtaatc ctttagcttt tttatcttta aagaatttag aattaaaatt
    20281 gtataatata cctctatagt cggctgtttt cattatattt actttaaaat tcttttcgtc
    20341 tttttcaaag ttagacatat ctttaggagt tatttgagct aagtctaatt ctcctgattt
    20401 taattgcatt gccttagcct tatcatctgg aacaatctta aagactactt tatctaatcc
    20461 tggttctttt acaaaataat cactattctt aacaagtgtt atactttgac ctttgtccca
    20521 tttttcaagt ttaaatggtc cagtacctat tggtttttga ttaaattcat cagtagctat
    20581 atccttacct tccaaaacat gttttggtaa tactcctact gttaaataat caagcattgc
    20641 tgtatttgga gcttttaaag taatttttat agtattatca ttaaccacat caatttttgt
    20701 tatatcttca taatttgatg ctatctcaga agcattatct ggattcatta tagtttctat
    20761 tgtaaactta acatcatttg ccgtaaattt ctctccatca tgccacttaa catcatctct
    20821 taaattaaaa gtatatgtat ttgttgcctc atcaaatttc cagtcctttg ctagacaagg
    20881 aaccacctta ttattttcat catgagctgt taatccatta aatattaacg aatttatttc
    20941 tccatgttca tatagtgcag gatttatact tgtatagtca ttacttccat aaacaagtac
    21001 ctttccatct ttaggcgtat ctgccttctt atctttgtct cctccactag aacaacctgc
    21061 cattagacta agtatcatta ctaaacttaa aacttttaac ttctttaatt tcatgatgct
    21121 cccccttttg ctttttataa aatatttttc aaagctttga ccccatttat ttaaatagat
    21181 atttcaaata cctcagtatt tgcttattta gtactcaaat gctgatttat aaattactag
    21241 attttttatt attattcttt cttatataat tacctatatt tgttatacac accaatgtgg
    21301 taaccaaaaa tatacccgga atcagtataa tccaccatct atttgaaagt aatgcttcct
    21361 ctgacaaaga taacatactt ccccaagaaa caatttctat tggtaaacca attcctaaaa
    21421 agctaagtgt cgattcagta ccaatagctg cgcctatgtt tgttacaacc atgaacatta
    21481 ttgatgccac aaaatttgga agtaaatgtt gctttaatac atagaagaat cctcctccca
    21541 tgctcttagc tgctagtatg tattcgctat ttcttatttg tctaacttct gttctcacta
    21601 tcttagatat attcatccaa cttgttatcc ctattactat ggacatagat actggatttg
    21661 aatttccaag tatagcttgt acaaatatta taattaatat tgaaggtata ctaagtatga
    21721 tttctgtaaa cctcatcatt gcatcatcta cgagttcaga tgctgaacca cttatactac
    21781 cataaacaat tcctataaca gttgatatta cagtggaaaa tagtcctata aataaagata
    21841 tttttcctcc ataccatatc atagaatata tatctctacc cattgagtct gttccaaata
    21901 aaaaagtttt atttggagct aaattagaac ttgctaaatc catgtatgtt ggttcatgtg
    21961 tcattataaa agatgagaat acacttccaa tgactatgat tgataaaata ataattgata
    22021 tatatggtaa ttctttaatt tttttagata aggttttctt tgtttctata tattcatctt
    22081 ctgctactaa aatataattt tctcctacaa tttcaaaatc actatattgt ggcttcatta
    22141 gtatcacctc tatcatattt cattctaggg tctattttat tgtttataat ttgagctaac
    22201 atattcccaa atactactaa agcccctgtt attaagcata aaactaataa catattataa
    22261 tcatgatact ttgcactttc aaaacaaagt gttcctaacc caggataaga aaaaactttt
    22321 tcaactacat aagttcctcc tagtatatga ggtatcgaaa tggccattat actaatatat
    22381 gatggcatta tatttctcag gcaatgctta aaaacaatag ttctattatt taaacctttt
    22441 gctttacata aaagcacata atcttctctt atttcctcta gtaatttatt tcttatcata
    22501 tatgtgtaat accatagatg gcttaatata agtactgtaa gaggtaagat taggtgtgat
    22561 atcctactta atatactgga ctcttctccc attgaataag caccactact tggaagtata
    22621 cttaagttta tactaaatat aagtatgagt actaaggcaa cccaaaatga tggaatacag
    22681 ttggttattg ttcctaattt gcatatgatt ctatcaatga gcttatcttc atgtaatgta
    22741 caaaatattc ctaacaataa ggctagcaca aaggtaagta tataccctga accacctaat
    22801 attatagtgt ttatatagac atcatttata acagaagtaa cattttgttt atatttaaat
    22861 gaaattccaa attccccttt tgatgcattt gaaatccatt ttatatattg actgtatatt
    22921 ggttcattca aaccaagttt tttcatagca ttttcttttt cttgtgtact cattctttct
    22981 actccatccc catagtaaga gattaatggg tctcctggag caagtcttgc catgtaaaaa
    23041 acaataaaag ataataaaaa cattactaaa ataaactgca acaacttttt cagtatatcc
    23101 tttaacaaac cccaaccccc ctttgttgca ataaaaaaac cacataaaag caaacgtaaa
    23161 gtaacgttaa aaccttcgtg gttccattat cattaaacaa aattaaattt tctatattta
    23221 tctatgagtt aattttagca tcatttatta actgtgtaaa caaacttttt aaaaattgtt
    23281 aaaatttcat caaattattt tatttatacc taaaataaaa tttttatgtt ctattcttca
    23341 ttattttcta taaaattata aaattttagg ttgactatat aagaaaagta tattatatta
    23401 gtttgtatgc aaacgattta agaggtgatt ttattgaaaa gtaattatga ctgttttaga
    23461 atagccatgc tcttaaaaga actttattct aaaactatgt acacagtaga agaaaatttt
    23521 aaagaaaatg gattaacaca ccaacagatt atagttataa aactggtagc tcataatcaa
    23581 gaacttacaa tatcacaact atgtgatgaa atgtctttag ctaaaggtac ggtttcaggc
    23641 ataatcagca gattagaaca gattggatat atagaaaaat tcaagaaatc taatgataaa
    23701 agaaatacat acgttaagtt tacaacaaca ggatttgaat ttgccacaaa ttttaaaatt
    23761 aaaatgcaag aaagttttga tgatattttt aaaaattgtg atgaaaacga attgagtgac
    23821 ttagtaaaaa atcttagaaa tatattggca aaagtaaagg agagataatt atgaattata
    23881 aattaatact tgcaatagta tttataacat cagctttaat tttctacact ataggtgtat
    23941 ttggagaaag aaaggcaaaa attttaaaaa agaaacatgt aattatattt tggcttgggt
    24001 ttatatttga tactttagga acatttacaa tgagtaatat agccaacagc catacttttg
    24061 aagtaaaatc tgctttatca caaaaccttc atagtattac aggtcttctt gcaattgtgc
    24121 ttatgctttt tcatgcaagt tgggctactt ttgtcctata caaagatgat gaggaaaaga
    24181 aaaaattctt tcataagttt agtatagttg tatggactat atggttagtt ccatacttta
    24241 taggtatgtt tattggtatg gttggatagt aaaataaaaa gtgtgtaaga aatactgtag
    24301 gtaaatttgt ataagacaaa tttatctaca tccttctttc acacttttac atatttatct
    24361 ataatactcc attatttctt tcatgtttct taatacctat atagaatatt taattgtttc
    24421 tatagtattt tattattttc tcacactttt tcatatatat attgttttac tattttttca
    24481 tatgtatata tgaaatattc cattatttct ataaatgttt tattatcttt atcatacttt
    24541 ttcatatata tattgcttca ctattttttc ttatttcttc atatacatat gaaatatttc
    24601 attatttcta taatgtttta ttatctttat catacttttt catatatatt gcttcactat
    24661 tttttttact tctttattaa atacttatgt ataacataca tttaataaac gctaactatt
    24721 aaacacctaa tacttgagtt actcctggaa cttcactcac caaaacattt tcaataatag
    24781 ctttgattgt catagtcgct cctggacacc cactacatgc cccttgtagt ctaactaaaa
    24841 ccacaccatt ttcatttaca tctataagct ctacatctcc accatctctt tgtaatactg
    24901 gttttatctt ttcctcaagc actttttcaa ctttttctct catagctatt ccccccagaa
    24961 atattttatt accaaaatta taccaatggt ttaaattttt gtccatctaa tgatttatca
    25021 aattcaattt ttgcttcatc aataatttta gtattcataa atacatcata agcactacaa
    25081 gccagtactt tagctgaatt tatcatagca gaaaatccta tatttgaacc tgctgatgaa
    25141 catgactgcc atgtatgact tgcaattcca acaggccaag ctgccattgc aaattgagcc
    25201 actggtatta cataacttac atctccaaca tcagtagaac cagctagtcc tttatctttg
    25261 tcaccgtcaa ctatttcctt gtgtatataa ctttctacaa tagatttatc attttgtaat
    25321 gatgttgcta cacctaatct ttcttctcta gtaagagtat cacacaattt ttttgcaaat
    25381 tcttcttctt caggagtatt tttagggcaa ccaacaaaaa ccatattgtc ataaactaaa
    25441 tcagtcaaac attggtttgg tatatagtca tatattccat ctgtaacctt atactccatt
    25501 tcagtttctg tcatcattgc tgctccttga gctactttta ttaatctatc aagaacatgt
    25561 tctgcatccc ttgctttttt acctctaata aagtaccaac tttcagcaaa tccaggaact
    25621 acattaggtc ttccaccacc attagttatg acatagtgca ttcttataga gtcaataaca
    25681 tgttctctca aataattagc tccaacattc ataatttcaa cagcatcaag tgcgcttcta
    25741 ccattatgag gagcttgagc tgcatgggct gttatccctt taaatttaaa ttttacagat
    25801 aagtttgcca gacttccacc tctccaaggt gcatttatat caaaaggatg ccatgtaaat
    25861 gcacaatcta catcatcaaa acagccattt atacacataa ctgtctttcc tccaccttct
    25921 tcttcagcag gacaaccaaa atattttatt gttccattaa atttattttc ttctattaat
    25981 ttttttatag aaacaactgc tcctacacct gctacaccca acaggttatg cccacatcca
    26041 tgtccagctt ttccttctac caatggcttt ctttctgcac tcacacattg tgatagctct
    26101 ggtaaagcat catattctcc aagtatgcca atcacaggtt taccctctcc aaaacttgct
    26161 ataaatccag taggtaaatt ttctacttct tcaattttaa atccttttga ctttaggtat
    26221 tctttttgaa tgctacttgc atacttttct tcaaaggcta attctggatt ttcccatatt
    26281 ttcttagata aatcaattaa ttcttctctt atttcttcaa cattatttat gatatactct
    26341 ttcataattt tcctccaaat atatgtattt ttgatatgct ttacagatta tattatatac
    26401 taacattcta tttattcaca attttttgtt aattaatttt attcatatgc tcttctatgg
    26461 agtatatctt atcttcactt tgcctcttca taaatttaat gtactctatc ttccataaag
    26521 tagtttcagt tttctcattt aacataaatt ctaatatatt aatttctctc attctaatat
    26581 cttcataaaa tactacacta cccaatattg ccaattctaa ttcacttaat gatgcaaaca
    26641 acattaaata ctcttctcca aataaacatt cagattcaag aatatcgata aagtcttttt
    26701 tagcattgat attttccttt attattctta ttttttcaat tatagatgta ctatctaata
    26761 tctcattgaa tatctctcta aacgattcat catccaattt actttcatca tcaacaatat
    26821 aatcttctaa gtgttcattt ttatttttac tcacagttac catactttta aaagtgttac
    26881 tttttattga gcttagcaca gattcaataa atatcttttc atatttttta atatatctta
    26941 ttacatcttc atcttctatg cttaatcttt ttattaatac ttcaattgct tccataagta
    27001 gtaaagttat ttttttattt attctaattt ctctgttaat ttcttcaaaa tcattataat
    27061 ccaaattact atctacttca gtgttaaaac tatcatctac ttcaatcaat tcaattatat
    27121 tactttcttc agaacctata actttatctt cagtaatatt attgtacata tttttaaatt
    27181 gtttttctaa aaattcatac tcatattttg aaatttctaa attagtcact tcatttccta
    27241 aaatagtaga aaaaatacaa ttatttataa taagttcaaa taaatttaca agtataacat
    27301 cacaatctat tttataaatc accccatagt cataaaataa tttttctcta tcttttttct
    27361 taaataggtt acaaaatcta ttttctatat ctatactctc aatataattc ttcacataat
    27421 aaataccctt aacatccata tcatctagtg ccaatggata atctatactt actggaacgt
    27481 cctgagcttc aaattttaca atataacttt taaagaaact tgataactcc atcaaggtat
    27541 cattatatgc tattgaatta gtatccaatt ttctactcat cattagttta taaaaatctt
    27601 tcagcctaac taactcttcc tctaatattt caatgcctcc aaggtacact tttttaacat
    27661 tcttagcagt caactccaca actctttttt ctatatctcc aagcttattt atatatgcat
    27721 caatagcata ccatattgaa atcaacagtt tttcggcaac ttctgttttt actgatgtgc
    27781 tttgaccatt tgtatatttt ttaatcaaat ccataagtat tagagatatt tcttgttgta
    27841 tattatatac ttctctttca tctatcactt tacaatttag acattcctta agtagagata
    27901 tggaatattg gttctttatt aaattatttt cgtttatatt aatattactt aaattattta
    27961 acatacaaaa tctctcctat catatattaa acttctccaa atttaaattt ctttgcaaat
    28021 tcgtctgctt ctcctcttac attgtccata ttgcctgaaa atttttcata aaattcaccc
    28081 agtatttcta taatctcatc atcacatatc ttgtcatcag tttcattttt taaataataa
    28141 aaaatttctt gcatatcatt aatagcctct aaataattgt ccacatttgt atattgtgat
    28201 gtatatatat tttctattaa ctgttttgta acttttatat ctaattctat tcttccatac
    28261 ccctttaaag tattatctct cgaatttatt atatctttta catcagattc agaaagagct
    28321 agaccataat ctccagattc tatattagtt tcaagcagtt catttctttc tatttccttt
    28381 aaattctgat ttatagaact caaaataata ggtgatatca tttttaaatt ctcctttttt
    28441 attttttcca ttgacttttt ttgtttttta tgctatattt aaattagtgt atattatttt
    28501 accaaccact tataatagta gtgttaaaag tggtttttgt caactcaaaa ttactatctc
    28561 aattaaactt ttcaattttc tcaacaaaaa aataccatca tttagatata taattttcta
    28621 taacaacttt taattcagta gttatttact aaaatctaaa caatgatata tttattaatt
    28681 ttatttatct tttttggctc tacttctact tttctttaca tttgagcaat ttctacaaga
    28741 aggtgaacag tattgagatt tagaatttgt aggaatataa attttaccac agtacttgca
    28801 tttatttaaa gaagaaggtt cacttgtaat tgcaaaggca tagatagtct caatagctgt
    28861 tttcaaagaa tcaaactccc atgcaataat tggtttatct aattggctta tagaaaatcc
    28921 tatcttttga ggattaaacc ctccagacat aatagtaaca ctttcagtta atagattaga
    28981 tgtattttta tatacacaaa tttgattaaa atgcttacac atatctttag caaaacttac
    29041 aatccaatct agttgttcag tgtagaactt tgaaaatact aaatctaaaa tcaatggtct
    29101 ctttccaaaa aactttggag attcttctct ctttgataca tctatacccc ttctatactt
    29161 tttaaaatac acatcttcat cacttgcaaa tggtataaac atgtttacat attcatctgt
    29221 actcaatata ttctcttttg taatataatt cttttcaatc atctgtactc tttcttctcc
    29281 aactatatct ctattatata cacttgaata tattaaaccc aataatccat acttttttac
    29341 aaattcaagt acttctttct ttagtttcat ttcttttgtc tcttttgata tatcttgtaa
    29401 tgcctcttgt cctatgcgaa ttatatctac tattatatca tctgctacat caaatgggtt
    29461 atacatggta aacacagcat cttctgttgg aactatatat aattcatctt cttcagtaat
    29521 tttatattca taatcactat acctaatcca atcacttgca aaattcccta ttaattctat
    29581 ttttttattc ataataatca ttcacacctt tcaatgtaat atataatttc gtattactat
    29641 tacactttta gtttattcca tattttctat actgtcaact attcttttta tatttttagc
    29701 atattaaaat ttataatagc ctttataatg gatttctaca gctaaatttc ttgtttattg
    29761 atgactaatt cataattaaa tttataaaaa ctatttacat ataaaattaa tctctttata
    29821 attgatatgt aatatatttt tacacttaca tattacatat caattataaa gagaggtatc
    29881 taaaatcatg gatagaaaac gtgaactaaa acaattatac aaagaaatga aatttgacac
    29941 aggtgtattc ataataaaaa atgatattac taaaaagatt taccttggaa aaagtaatga
    30001 cataaaaagc aaatttaact ctctcaaatt tcagcttggt gctggctcat gtatgataaa
    30061 agaattaaat aatgaatgga aaaaatatgg tgaaaaagca tttacatttg aagttttaga
    30121 acttataaaa catgatgata acaaaacaga gaaagactat ttagaagaac tagatatttt
    30181 agagatgatt tggttagaaa aattaaagga agataatact tatgaaattt attccatata
    30241 aaaaatcata taatacatat aatataagaa aaggagatag tatatcaaaa tagacattta
    30301 gttcatgaga tacttttttt atataaaata aagtatattt tcataatttt atcaataaaa
    30361 aagaggctta tctccatttg atagcctctt cccatatatt ttataccatt ataaaatgaa
    30421 caatctacta attttcaatg tatatattca ttttactaat aacactccat tacttcttta
    30481 cagcatccaa acattgctct ataatactct tatcacttat acctactgct gttactttgc
    30541 tagctccact taatatactc ttatcacttt tatttgaaac taaaacaaca ggagcatttt
    30601 ttgcaagtgg tgatgcaact aaagcataaa ctaaatcgtc tccacttgtt atatagaact
    30661 cttttgctcc attatagaac ttttcaataa catttttatt agtttgatat ctatcaacac
    30721 cgccaattct agttgctcta tatctgctca ctatgtaatc acttaatgta gactctcctc
    30781 caatagcata tactggaaca ggagaaactc caaaccatgg gtctaagtct gtgtcttctt
    30841 ctgctgaagg tatatctttt gtcaatatta taggagctcc atctctataa gcaacagatg
    30901 caacacttac tgcatcagct tcatccttaa atccatttac taaaaacatc ttatcactgt
    30961 ttttaatttt ttctatttca cctgcaattt tataacttgt atctactcta tctacaccat
    31021 caattcttat aacttgcatt cttctcataa gtaacatttt ttctacatct ttacttatag
    31081 aattttctcc acctattaca tatatcttag taactctatt cagtctttga agtgttgctt
    31141 ctggtatatc atccttatta gttaataaaa tagctgcatt atttactcct gcaagaccac
    31201 ttgcagcaat cccatctacc attgtagaat ctgcattgat aagaactgct gttgtaaaat
    31261 cttgcttatc tgaaataagc ccagctgttt catatttatc tactccttga atattttcaa
    31321 tcttatctag tgcgtttatt gatgttggaa aactaacact taacagtaat gctgaaatac
    31381 ctaacgccaa taccttttta ctaatcctca taaattacct ccctaaaaca aatatattta
    31441 gtattagtat aatataaaat catttaaaaa aagtttaaaa atagttacac ttttttataa
    31501 tttaaataat tttagactaa acacaattca tccattaaaa taacttcatt tattctatat
    31561 gctaagccat cccacgtttt ttttgacata tctacagatg ttttctcatt tgagttattc
    31621 aataaagatt gtatcttaga atctattgca ttatacaaat tattttcaaa atcatataac
    31681 tcttcatctt ttggaatacc ttctttctcc ataaaaggta gagaaatata ttctatcttt
    31741 ccagaattat taatctcact accaatccac tctttaacac caagaatatc agtagtgatt
    31801 acatctgtgc cacaagataa agcttctaaa actacaactg gtaatccctc ataaaatgat
    31861 ggtaacacaa atatttgtga cctgttgaat agctcagcta aatctctctg ttctaacttt
    31921 cctaggaaat tcattttaaa tggagactta cttgccagtt taactatctc attatatgat
    31981 tcgatatcgc ttccagtacc tgcaaaattg acttctatta aatctttact atattttaat
    32041 ttagatatag attttataaa tggaatcaat ccctttgatt tacatatctt acctgcaaat
    32101 actattttta ttttatcatc ctttatttta taatttttat tataaaatat atcatcatta
    32161 taaccactac caattacaac tactttactt tcacttactc caaaagtctt tataatatca
    32221 tatttctgat tttcatgaag agcaaatatt aaatctaatt tccttatatt tgctattatg
    32281 tattctttct ctaaatcaat ggtatttaac tgtcttaaac aagttccatg acaaatagac
    32341 ataaccttta tatcttttac tatttcccta acaaatgcag ttaagaggta caaatgatga
    32401 catattataa gttctggttt aaaatcattc atagccttat ctatatttac tttaaattga
    32461 tatttcaatc tatttatcat gtctatattt aaatctttat atcttgtact ttcatatggc
    32521 atagaatcac tcatacctac aacaggaaaa tttaactccc cacaattata ctttactgga
    32581 taaaaactta cttcacttgg aaaacaattt acatcatcat ttacatctat acctgcaatt
    32641 acagcttgct tatgaccgat tttttcgaac ccttttatca taccagacaa atatatacca
    32701 ctacctgtac tatttggttt ttgtgttatt atatgaagaa ttttcacttt tcacttgcct
    32761 cctttctaaa attaaatagt tttatacagt ctaatcatta tatatatcta aatataaaca
    32821 agatgaatca tcttttattt taaatcttgg cactttaacc gctttatagt cattatcttc
    32881 aaaatccctt actttattat gtatatatcc tataccaaat ttttctgcta tacgtatcaa
    32941 ttcttcttct tttattagat tatatctatc acatgcactt gtaaaaccat cactcgttag
    33001 catcaattga aaatcttttt ttatttcaat gtatccatat atagaatttt ccacagcttc
    33061 ctcatcaaaa tccaatatcc aatagccctc tttcgtattt ttcttcaatc tattgcttac
    33121 tattgtatcc ataacactag ttctaatctc atcaaatgcc atctcttcca agttagaaag
    33181 tttactcatt tcatcaaata cagtattatc aaatttacaa atactcctat cttttataac
    33241 tttggaatct ccatttttaa taaacaaagc acaatctcct aataaaaaat actctacttt
    33301 attttcatga aattttacaa caactataga actagatggt aaatctaatt tttcaacctt
    33361 aaacccattt aatcttagtt catactcttt ttttacttct attattccag tattaataat
    33421 actctttaat gattcttctt tatttatatt tttatataaa tacctattcc accactgaac
    33481 ataccacctt gcgtcacttt cagttgacac taaatttttt ccattaagtc ctgtagcacc
    33541 atctaaaacc catgccccaa atggatttat accgactaca tcttcattaa atttagctgt
    33601 tccttgatta cataataggc tatagtttct tatatttaaa gccatatcaa cctccaaatt
    33661 gaatatctaa aaataaagtt ctatttaaaa ttatacagca aataaaaaaa tctacaacaa
    33721 aacttgttgt agatttttac ttaatctata ttatctttat actttcagta ttttaatgat
    33781 ggaataatct atttttagta aatgccatga ctatgttata cttattacaa gttaatataa
    33841 cattatcatc acgaatagaa ccacctggtt gtgctacaaa acttacccca cttctttttg
    33901 cacgttctat attatctcca aatgggaaaa atgcatctga accaagtgct actcctgtta
    33961 aagttttaag ccatgctctt tttccttctc cagttagagg ctctggtttt tcttcaaaaa
    34021 agttttgcca tatgccatca gcaagcacat ccatataatc atcagaaaga tatacatcaa
    34081 tagtgttatc tctatctgga cgacctatat cctttttaaa ttttaagttt aatactttag
    34141 gatgttgacg aagataccaa gtatcagctt tgttacctgc aagtctagta caatgaatac
    34201 gtgattgttg acctgcacct acccctatta cttgtccatc tttagcataa caaacagaat
    34261 ttgattgtgt atattttaat gtaataagag ctataattaa atcacgtttt gcactatctg
    34321 taaaaatttt attatcagtt ggaatatctt ttaataggtc ttcatttatt aatatttcat
    34381 ttctaccttg ttcaaaagta attccataaa catcctttgt ttcaataggt tcaggagtat
    34441 aattttcatc tatttttaca atattatagt tgcctttacg ctttcctttt aatatttcaa
    34501 gggcttcatc tgtatatcct ggagctatta taccatcaga aacctctctt gctataatag
    34561 ttgcagtctc cttatcacat acatctgaaa gtgctataaa atcgccataa gaagacattc
    34621 tatctgctcc tcttgccatt gcataagcac aagctaatgg agaaagctct aaatcatcaa
    34681 caaaatatat ttgctttaaa gtatctgata aaggtacccc tactgctgct cctgctggac
    34741 ttacatgttt aaatgaagtt gctgctggga gacctgtagc ttcttttaat tccttcacaa
    34801 gttgccaact attaaatgca tctaaaaaat ttatatatcc aggttttcca tttaatactt
    34861 ctataggaag ttctccattc ttcatataaa tctttgatgg tttttgattt ggattacagc
    34921 catactttaa ttctagttct cttgccatat actcatccct ctctataata aattaatcat
    34981 aagtttgatt aatcctatat taattaaatt atttgtacta ataaaattat atggcatatt
    35041 tatccattaa tcaactatat tttttaaaac tcctattcct tcgactttac attcaactat
    35101 atcgccatgc tttaaatata cttgaggatt catccccata gcaacccctg ctggagttcc
    35161 agttgaaatt atatctcctg gctttagagt cattcctctt gataaatcat ttattatagt
    35221 aggtatatca aatataaagt actctgtatt agaattttgt cttacttctc catttactac
    35281 actacttata tctaatttta aaggatgttc aaattcttct ttatgtacta tacaaggtcc
    35341 catagatgta tgtgtgtcta agctttttcc tctaaaccat tgaacatgtt tatcttgaag
    35401 tgctctttca cttatatcat ttactattgt atatccaaat atatattcat aagcatcttc
    35461 ttttgatata tttatacctt ctttacctat gattactgca agttctgatt catagtccaa
    35521 cttctctacc aaatctccat gtaagcttat cttatcatcc actccaatta ttttgtctgc
    35581 tctcttagaa aaataaattg gataatctgg cataactacg ttttttataa ctccatctgg
    35641 gatttcattg acatggtctt tatagtttag acctaaacat ataatatctt ttttaggtct
    35701 tacaattggg gaacataatt taacttcttc taacttataa cactttgcgt tttcaaatga
    35761 attgtttttt attttttcta aatctcctgt agatacgttt tcaataaaat cattcatatc
    35821 agtatataat ttacttaatc ctaaactatt aatttcatat atactatttg tttctgaatt
    35881 aaatacacct attttttctt cattgctact acaaaaagtc acaaatttca tttttattcc
    35941 tccattcaat aagttgatta atattattta atttttatta gtttatataa attgtaattc
//
LOCUS       DACTZW010000038        35490 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.038, whole genome shotgun sequence.
ACCESSION   DACTZW010000038 DACTZW010000000
VERSION     DACTZW010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 35490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35490
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.038"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            117..872
                     /locus_tag="JAM15_09940"
     CDS             117..872
                     /locus_tag="JAM15_09940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1835 domain-containing protein"
                     /protein_id="HAT6798572.1"
                     /translation="MAHICFEDICYLLLKEAMKLKLIPHNKIVLFEDDLSIGNISDVN
                     NYELRENIFKIRNVFENNPKLLFKPDLLEDRKLSKCRNIIIWCANNPKDLCGVYYVVS
                     KFQDKNIKIALVDEKKTEDALIRYSFTSEMSPEDFPFFLDKTLEIGFNEKLEFKNKWD
                     VLVKENSIFRALVGKEIKSVEETYFDKYILRNISDKWQPLIEVVANCMFEDEMRVKDW
                     FILWRLEKMASLKIVKIKGSKGDFYSDKEIRKV"
     gene            complement(1511..2782)
                     /locus_tag="JAM15_09945"
     CDS             complement(1511..2782)
                     /locus_tag="JAM15_09945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanine deaminase"
                     /protein_id="HAT6798573.1"
                     /translation="MLKVLKGNIIFTKTSETFTVFENSYIILEKGKVKGIFKEIPKEY
                     KNLKVVDYTDKLIIPGMNDLHAHASQFKNLGMAMDKELLPWLETYTFPEESNYKDIEY
                     ATKMYKKFVKELWKSGTTRIAVFATVHKEASMKLMDIFKEVGLGAYVGKVNMNMNCPD
                     TLLENTQDSITDTEEIINKYSDTDSIVKPIITPRFIPSCTSELLKGLGDLCLKYNIPI
                     QSHLSENYDEIEWVRSLEPESKFYGDAYNRYNLFGQTPTLMAHCVHCSQDEIDLMREN
                     NVMAVHCPASNFNVGSGAMPIRKLIDNNIRLALGSDISGGHTLSIFKAMVSAIQLSKL
                     YWVNSGKKYNFLSLSEAFYIATKSGGSFFGKVGSFEEGYDFDALIIDDSNLNHDNYSI
                     LERLERFIYVGDDRNIIHRYVCGKLIEEPNI"
     repeat_region   3429..4316
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=3429..3457
                     /rpt_unit_seq="gttttatattaactaagtggtatgtaaat"
     gene            4725..5012
                     /locus_tag="JAM15_09950"
     CDS             4725..5012
                     /locus_tag="JAM15_09950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798574.1"
                     /translation="MKKILYALYSFIVIIANFRLKEKNYNFILLAIFFILLLIQNGVL
                     KTGYQNRATFYQDNYFNGEDKNDKIKFITIKIFIFLSLPLCFNILFNYLTS"
     gene            complement(5550..6101)
                     /locus_tag="JAM15_09955"
     CDS             complement(5550..6101)
                     /locus_tag="JAM15_09955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6798575.1"
                     /translation="MSINTVIAKNLNRLRNERNLSLGQLAELSGVSKVMLSQIEKGDS
                     NPTVNTIWKIASGLNVPYTAILEQPQNETFIVSKTDIDVQVSENKDYRLYCYYPNTPT
                     RNFELFQMELEEGHSYTSVGHSEKSQEYIMIIEGQLKLEVNDSIYQLRENDSICFSAE
                     SIHTYHNQGEKTLKAVIINYYPV"
     gene            6292..7254
                     /locus_tag="JAM15_09960"
     CDS             6292..7254
                     /locus_tag="JAM15_09960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HAT6798576.1"
                     /translation="MRVLNNVTEAIGNTHMLHLSKIADEFGVQGNIYAKMEYLNPGFS
                     KKDRVALQMITEAENAGLLVPGQAVVELTSGNTGTGLAIACACKGYKFIACMSKGNSM
                     ERARMMKALGAEVVLVDQMPNSVHGQVSGEDLALVEIEAQKIAKERNAFRADQFNLEA
                     CNHAHEKYTAEEMWEQLDGNIDVFVDFLGSGSTFAGCSKTLKKHNSSIKCYVVEPETA
                     AIYSGKEITDQGHKIQGGGYSMDLPLVDKKLIDGYIQVTDEEATDVARKLAKLEGVFA
                     GFSSGANVCAAIKLLKSSEKGKNIVLTLNDSGLKYLSTDLYEEL"
     gene            7549..9393
                     /locus_tag="JAM15_09965"
     CDS             7549..9393
                     /locus_tag="JAM15_09965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAT6798577.1"
                     /translation="MQKRILRNFIFTGKNILSKLVFIIKYNFSTLILFELFHKGLALF
                     FIWPSIRYIFDILIKSLHIVYLNMDNFIKVLTNPMSIVLIILSVIILAFYAFFEFTSV
                     IICFNKSIKYEKIGLFELFKISFKNSIKLLYPKNILLFIFVILIIPLVNTVLISGFIG
                     KIQIPEYILDYIKSDIILNIIYMIFLLIIYISVIRWIFSIHEITLNTENFKRARKESV
                     NLIKGKIIRTIIYSLILSLVVAIIGYAIYHSGIIFIGIWTKYCTDMEFLKNVFINRCI
                     AFEEYFRLILSIFIFILDIGFISATYYQYKGVSISKNNIKKEKKSISKIVFNLVLILL
                     ISYIESVAFSSHINGMFNTSFSFYTTAIAHRAGAEMAPENTLAAIEEASHAKADYAEI
                     DVQETKDGELIVLHDSNFKRTTGVDKNVWDVNYNEVKTYDAGSFYYYGKGYYDEKFVG
                     EKIPTLKEMIKYSKGKVKLLIEIKFNGHEKGDVVKKVVQLIKENNFENQCIVASMDKT
                     ILQKVKKLDENLLTCYFMAIAYGDFSKLNYVDIYGIESTFVNKTVVEKIHKMNKKIFV
                     WTVNSDSLIEKMLDLNVDSIITDNPYLIESAIYWKKNGFISQVSDYLF"
     gene            9715..10299
                     /locus_tag="JAM15_09970"
     CDS             9715..10299
                     /locus_tag="JAM15_09970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004072597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HAT6798578.1"
                     /translation="MTEREKMLAGELYDCGDIELLTQWHKAKDLVRDYNQTDSSELEK
                     KEKILNELLGGKGKNLWITAPYYVDYGNNIYFGNNCEVNMNCTFLDDNKIIIGDNALI
                     APNVQIYTAFHPTNAGDRFGNAKEDGSFEFCKTQTAPVTIGDNVWIGGGAIIMPGVTI
                     GDNVVIGAGSIVTKDISSNMIAYGNPCRIIRENK"
     gene            12159..13181
                     /locus_tag="JAM15_09975"
     CDS             12159..13181
                     /locus_tag="JAM15_09975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798579.1"
                     /translation="MVNWEIKKLAKSKSMFISLGILVLILMISIFITPVLETESYYID
                     KEKGRIEDTRSGIDIGNEKFQNKINVLKQFSNQTDTGEFSKKIELMSKKKLDNLSVNE
                     YKDISFWKVFNYRVTNSLINVGMLIIISIIISNIYVDEVVTSVKDIILSSKEKKKALK
                     SKIFVALLVPLVIYFVYLMGIFIITCMQQGVPVNGDLESFRIVDNVVALKTNLSITKY
                     VILNIGIELLMFEGWAMIAIFGSFISKSSISSISFFIFIISITKIMSVVHILPKKLLS
                     VVSNVNYYDLIFGFNKIIGNYLGDIMIFKVNIDIVNIAIGLLMAILIGVMSLCFLVIK
                     SDYISR"
     gene            13195..14082
                     /locus_tag="JAM15_09980"
     CDS             13195..14082
                     /locus_tag="JAM15_09980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003373897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6798580.1"
                     /translation="MNKLEIENLSKIYGKKVANDKITVTLENGVYGLLGPNGAGKSTL
                     MKQITTLIKPDEGQILYNGEDIFKMDADYRNILGYLPQEFGVYKNFTAKEFLQYIGAL
                     KGLRGKYLNSKIGELLDLVGLYDVRNKSIGKFSGGMKRRVGIAQVLLNDPKIIVLDEP
                     TAGLDPQERARFRNLIAKMSRDKIIILSTHIISDIESVAKETIMIKDGKLLMKGTHKD
                     ILSHMENKVYNVQVKNECEVDDIQSKYKVVSIQSDIDSVVLRIVSEDIPSGDNIQPVQ
                     AKFEDVYMFYFDLEDAREV"
     gene            14088..14861
                     /locus_tag="JAM15_09985"
     CDS             14088..14861
                     /locus_tag="JAM15_09985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6798581.1"
                     /translation="MMYLVKAEMIKILKSKSVWIIWLFLIFFGFLLIRKFDVLDTYAD
                     IFYKIEGSIPLIGLIMFIITSGNYIKEYDSNMTGLINTTKKGKKSVVLSKLVANGLIL
                     SIINISFILLVGIRGFSFFDFKNLNEPIHNLWYFGNSNLNLTVIQMYIIVILTTIFAS
                     FIFAQIGLTLSSIFKSAVIPFILGGLIMAIPYFSVGFIPDKAIKFMSVTPNWIMMSQQ
                     MVRYNVPSILIVFSIVISIILMIVLTKITYENFTSSKRF"
     gene            14973..15698
                     /locus_tag="JAM15_09990"
     CDS             14973..15698
                     /locus_tag="JAM15_09990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012450879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6798582.1"
                     /translation="MENRVLIIDDEVEILKLLETVLKKEGLNNIYTAKTKKEGLELFK
                     SINPDLIVLDIMLPDGEGYDICKEIRKTSNSPIIFLSAKTEELDKLLGLAIGGDDYVT
                     KPFSPKEVAFRVKAHLRRLSYFSDVQNESKNLNKNEEKIISFGPYILNESRAELIKDG
                     KSIGLSAKELKILSLFAHNQNQIISKEKLWDKVWGEDYVGFDNTIMVHIRKIREKLED
                     NPSKPEYILTIKGLGYKLAVKED"
     gene            15702..17105
                     /locus_tag="JAM15_09995"
     CDS             15702..17105
                     /locus_tag="JAM15_09995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAT6798583.1"
                     /translation="MKWKITRNFIFTIVFVAISVVIINIISILYVISTNSFFKVVDSG
                     NNPEEFARSFEKDLYEKDGEFKLSKIGAEKLEKSNSWIQVLNDLGEEVYGVNVPKDTP
                     KKYTPFQMVNNYKYIETKYVNFVLEKYLNKKHLNIIVGIPSRDISRIILTYSQNNIKK
                     TLNKVIIITLVIDSVVALGVGYLFSRKLTKPISSILWSIETMANGNYSLYLKDRGIYE
                     EVFKNINMLADTLRVNEVERKENEELREEWLANITHDIKTPLASIQGYAEIINDKDYE
                     FEEDEIREYTEIIYNKSKYIKDLVDDLNLSTRLKNNTIVLDKKKINLVSLVRDIIIDI
                     LNDNRYKNRNIEFESNEDLIEVYVDSILFRRAITNLIFNSIVHNSEGTLISVEIVKKD
                     NIEIIIKDNGIGISKSDLKHIFKKYYRGTNTGEMHKGSGLGMAISKEIIEIHKGKIYV
                     SSEIGIGTKIIIEIKQN"
     gene            17116..17940
                     /locus_tag="JAM15_10000"
     CDS             17116..17940
                     /locus_tag="JAM15_10000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraX"
                     /protein_id="HAT6798584.1"
                     /translation="MDFFKKGISGFTIKILALIFMTFDHIAAFMPQTMQIPIWFHWVG
                     RISAPLFIFMAVEGFYHTSNRKKYISRLYIWSVIMAIGNQIINNVFSHPEGAIIINNI
                     FSTLFLIAIYLQAIEFIKKFRKEKEIKYFIIGLLMIIIPIILGIFTVALLFKVTNRVI
                     TLFMILVPVPFLVEGGPIWIILGIIFYLCRGKKFSLSICYVLMCIFIFTTMSNGDYSL
                     KNSILQNYQWMMIASLPLMLLYNGEKGKSMKYLFYLYYPIHVYILYILGIYLINGF"
     gene            complement(18265..18885)
                     /locus_tag="JAM15_10005"
     CDS             complement(18265..18885)
                     /locus_tag="JAM15_10005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HAT6798585.1"
                     /translation="MKVLLINGSPNQYGCTYTALNEITKVLSKHDIKTEILYLGKEAI
                     PGCISCASCFETGKCIRNDKVNELIEDLDNIDGIIIGSPVYFSSATGQLTSFLDRLFF
                     IAGSRMATKLGASVVSCRRGGASATFDQLNKYFSISNMPIVSSQYWNQVHGFTPEDVM
                     KDEEGLQTMRTLGENMAWLLKCISAGKKAGIKEPQYEETIMTNFIK"
     gene            19151..19483
                     /locus_tag="JAM15_10010"
     CDS             19151..19483
                     /locus_tag="JAM15_10010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6798586.1"
                     /translation="MSIDCISNTDLSETGFSYTLSLISGKYKMIILYCLVEFEVVRYN
                     ALKRYINTISYKTLSLSLKELEADNLIIRTEYPQIPPKVEYSLSERGKSLIPILDAMC
                     EWGERNRP"
     gene            complement(19603..20244)
                     /gene="pcp"
                     /locus_tag="JAM15_10015"
     CDS             complement(19603..20244)
                     /gene="pcp"
                     /locus_tag="JAM15_10015"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HAT6798587.1"
                     /translation="MKILLTGFDPFGGELINPAQEAVERVNNNINGAEIIKITIPTVM
                     TKSVEAIDKAIQEHNPDIVISVGQAGGRFDITPERVAINIDDFRIKDNEGNQVIDTVI
                     KEDGEPAYFSKLPVKAMVKHMNENKIPASVSNTAGTFVCNHVMYGILYMIDKKYPNIR
                     GGFIHIPYTTSQVIDKKNTPFMSLEEIVKGLELAIEACIIYKEDVKEIGGEIS"
     gene            complement(20265..21197)
                     /locus_tag="JAM15_10020"
     CDS             complement(20265..21197)
                     /locus_tag="JAM15_10020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HAT6798588.1"
                     /translation="MQNFINISLEIFYALMGFLMIVIAYKSFTTINNNKKYGTSLFWI
                     LISLPFIFGRLIPANIIGIILILSSLLTLSKQVVFAKYEEPDENFGKEQADKLKNKIF
                     IPSLILAFAAVVVAMSLSNFDNSSQFAIGVGSIIALISALIITKAKPATSVQDGSRLL
                     QQMGPASMLPQLLVALGALFTQAGVGEVISTMISGVVPADSRLFGVIAYVLGMVIFTM
                     IMGNAFAAFSVITAGIGIPFVLSQGGNPAIIGALALTAGYCGTLLTPMAANFNIVPAA
                     LLECKNDYIVIKYQAPVALVLIIAHILVMYFLGF"
     gene            complement(21219..21884)
                     /locus_tag="JAM15_10025"
     CDS             complement(21219..21884)
                     /locus_tag="JAM15_10025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HAT6798589.1"
                     /translation="MIKLIGILIVVIGFILKIDTLFTVLLAGVATGIVAGLDFNQIFT
                     ILGDSFVSNRGVSLFILTLPVIGVLERYGLKQRAVSLIEKLKRLTTGKVLTIYMIARQ
                     IAGALSIRMSGHPQFVRPLVNPMAQAAGLSNSDELKESDEEAIKALSAASENYGNFYG
                     QNLFAGSSGVLLIASTLTQFGYNVTGLNIVKASTIMAVIALVVATIQFTLYDKKLNKS
                     HKK"
     gene            complement(22431..22907)
                     /locus_tag="JAM15_10030"
     CDS             complement(22431..22907)
                     /locus_tag="JAM15_10030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HAT6798590.1"
                     /translation="MNTIIIYSSKYGCTKDCANILKNKLSDNVTIVDINNNNNKIELS
                     KFDKIIIGSSIYVGSVSKKIQVLCNDNVELLNKKQVGIFLCCGFSEQADKYLKSNFPS
                     SLLESANAIGIFGSEARLEKMKFLDKLIMKAVSKGNYDSFRISQDNIDNFLINLNS"
     gene            complement(22910..23314)
                     /locus_tag="JAM15_10035"
     CDS             complement(22910..23314)
                     /locus_tag="JAM15_10035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HAT6798591.1"
                     /translation="MKIRNKATNKKKKYVKISIALFFVFICIIIVIVSNLKPENLVVK
                     DIDINNVKNGIYTGSADNNLVKATVSVEVNNGKIQNINILKHDHLLGKPAEKITTSII
                     KQQSLDVDAITSATYSSNTIRKAVENALRKGE"
     gene            complement(23289..23918)
                     /locus_tag="JAM15_10040"
     CDS             complement(23289..23918)
                     /locus_tag="JAM15_10040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAT6798592.1"
                     /translation="MSIKERRKNEKEEMKKKIMDASIEIINQHGYENLSIRKIATKIE
                     YSPTTIYLYYKDKAEIISDMTNKLYNTVESNAIDIMNNCSSLPIDKQIIEIMTSFIKT
                     LSSEPEMAKAIMHSRMNIIFASENTNNTPSNNGIKMLDKFLSIGIEQGIFKKNIDKSS
                     WMLISALLGFVLCVVENKLYSLHNFSQLIENFLDILVGGLYNENSQQSY"
     regulatory      24283..24326
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            24427..25395
                     /locus_tag="JAM15_10045"
     CDS             24427..25395
                     /locus_tag="JAM15_10045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HAT6798593.1"
                     /translation="MEKRKVIIDCDPGIDDSLAILLALNSPELEVIGITTCCGNVPAN
                     IGAENALKTLQMCSSLNIPVYIGEEAPLKRKLVTAQDTHGEDGIGENFYQKVVGAKAK
                     NGAVDFIINTLHNHEKVSIIALAPLTNIAKALIKDKKAFENLDEFVSMGGAFRIHGNC
                     SPVAEFNYWVDPHGADYVYKNLSKKIHMVGLDVTRKIVLTPNIIEFINRLDKKMAKYI
                     TEITRFYIDFHWEQEGIIGCVINDPLAVAYFIDRSICKGFESYVEVVEDGIAMGQSIV
                     DSFNFYKKNPNAIVLNEVDEKKFMYMFLKRLFKGYEDIIDSVEGVI"
     gene            25397..25960
                     /locus_tag="JAM15_10050"
     CDS             25397..25960
                     /locus_tag="JAM15_10050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAT6798594.1"
                     /translation="MKRKICVKTITLIAFGISINIIGAFIAMGLRLPVYLDSIGTIMI
                     ASLLGPKYAVVTGVFGSLISGITFDVYSLYFAPVQISTGLLAGIAFKKNFLRGLKTPL
                     GVLLFAIPTSIISSIISAFLFGGMTSSGSSYIVQILKVLGLGDVFSVFVTQVFTDYGD
                     KLLAVVLVNLGLNAVPKTLKVSLTGGK"
     gene            25968..26657
                     /locus_tag="JAM15_10055"
     CDS             25968..26657
                     /locus_tag="JAM15_10055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009261906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HAT6798595.1"
                     /translation="MDRYSEITNKNQREIVLLKGFPCIWGKCSFCDYIDDNSNLEEEM
                     NKLNLRVLKNVTGKYGVLEVINSGSCFELPKDTLEKIKCIIKEKNIKKLFLESHWSYK
                     NRLKEMREYFEIPVVFKIGVETFDNDFRNNILNKNANFKTPQDVKEYFDSPCIMVGIK
                     GQTKEMIDKDIEIILNTFEKATVNVFINNSSSIKRDEELVKWFVSKYKFLDENPNIEV
                     LYNNTDFGVGD"
     gene            26784..27512
                     /locus_tag="JAM15_10060"
     CDS             26784..27512
                     /locus_tag="JAM15_10060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HAT6798596.1"
                     /translation="MMFDRGKWNKLDYNELLEYMMSIKDIKYRDFNKKLIPGTENIIG
                     IRVPNLRKLSKEISQGNWKEFLEVAEDTYYEEVRLQGMVIGNINSNFEETLYYVKRFI
                     PKIDNWSVCDGFCSGLKSMKKYKENMYDILKKYVYSKNPWEIRFALVMFLIYYVDDKH
                     IKEIFEYCNNIQSEEYYVKMGMAWLLSICFIKCEEETFLYIKNNNLDDFTYNKMLQKI
                     IESNRVDLEKKNIIRSMKRKTRRC"
     gene            27526..28200
                     /locus_tag="JAM15_10065"
     CDS             27526..28200
                     /locus_tag="JAM15_10065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAT6798597.1"
                     /translation="MNNNEDRIDKFLELQSKGFKFAEIAQNLKISQSTLRTFLNKKGY
                     KSEKGKYILKDELNYNKSLDNRNLEEEKAKEYEKSKKNTISNRKKVSTKKKISNEKAL
                     SKSVEQIEFNDTGLKNAKPKQNVKPKKDRKINITQEDLDKLCEVYDWYLEVKDYNIKP
                     KKVSNKKDVHIDDEHIDELKTTRIRIDKEIWNDFERLCSNSNFEKHQILTQALKEFMK
                     KYKNLL"
     gene            28226..29062
                     /locus_tag="JAM15_10070"
     CDS             28226..29062
                     /locus_tag="JAM15_10070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798598.1"
                     /translation="MNKIVKKSISLMIILTIFIFMLTACEKDEQPDSVDIQTEDKNEI
                     KIDEGNAKVLNIGKSEIINIDEGDKVDTSTKVENNSTFNISNVELIYNEYDENKKIIS
                     SDSKALLDMTLMPGKVAYIECGHKTFVKGVEVYAYEYEAEGKIVYVNLKENTINIRNN
                     NIKLENSSQYEVLSTSELKKVNESNEGITYQVKVKNSSSKDLGNIILKTAEVNENGEY
                     LTVNRVPSYKILKPSEETDIDILCSTKAKSVEIVGYTYDDIKEKANVDIDLKSHKVKI
                     DK"
     gene            29078..29749
                     /locus_tag="JAM15_10075"
     CDS             29078..29749
                     /locus_tag="JAM15_10075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6798599.1"
                     /translation="MKVLIVEDNKILLESVVEELSKHFETEKCEDGEEALYLVNQNIY
                     DLVILDLMLPNINGFDILKKMRVNNIDTPVLILTAKETLDDKVEAFTIGANDYLTKPF
                     YMEELVARVYAILRTNGKIKERNGLEFKSLYLDTLEKRVYIEKEEIKLQNKQFNLLEY
                     FVLNKGSILLKEQIYDRIWGIDSDATIEIVEVYVSNLRKKLSKYGYDKYIKTKRKVGY
                     IFDDK"
     gene            29739..30971
                     /locus_tag="JAM15_10080"
     CDS             29739..30971
                     /locus_tag="JAM15_10080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAT6798600.1"
                     /translation="MINKNVFTSTKNHLIKMYIIVVGSFLIIFSIFIYSYFRGLTYSG
                     IDSEINDELEYIVSQFKRTSFLNPIRLKDPKDMVYVYEDGRISYYTQNEYFDELLPDR
                     RLDKKNSFFKYTENGYTFRELNVDVGRYQIQIIRNIDSEMNSLRQLTSVLIIGILISV
                     IITYFVAVYLTRKALIPIETAWKNQAKFIQDASHELRTPITIVSSKLESMLKSPESTV
                     NDEVETIATAMKETRRLKKMITDLLSLTKEDSIVKVNLEEIDLEKLLEEISEDYIDIA
                     EFQEKRFVFNSKLKNKVIITDKNKLRQLILIFIDNAFKYTKLGDEIALELKEDIEDEV
                     TLLISDTGIGIKKEEIPLIFDRFFRSENVRNKDLEGSGIGLSIARMISLNLSIDINVT
                     SDVDIGTTFELSIPKKLK"
     gene            31121..31438
                     /gene="trxA"
                     /locus_tag="JAM15_10085"
     CDS             31121..31438
                     /gene="trxA"
                     /locus_tag="JAM15_10085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HAT6798601.1"
                     /translation="MAKVINTSEFRSSVEGSKGVVVVDFFATWCGPCNMLGPVFAELG
                     EEMKDKARFVKVDIDESLEIAQQFNVSTVPTMIIFKDGKPVETLIGFMPKNKIEMQVK
                     SYL"
     gene            31455..32333
                     /locus_tag="JAM15_10090"
     CDS             31455..32333
                     /locus_tag="JAM15_10090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAT6798602.1"
                     /translation="MRYDIAIIGSGPAGLSAAINAKIRNKTIIMFGNDNLSNKLVKAP
                     SIDNYLGFYDISGDELKDKFKSHIDSMDISIENKRINNIYAMGEYFTIMSGNDMYEAT
                     TVILATGVEYTRPIKGEEEFLGRGVGYCATCDAPLYRNKKVAVIGYNEESKEEANFLS
                     ELTSKTYFIPMYKKDNLMRSSDNLDDSIEVIHDRPVQIDGDKLVNKVSFKENHIEVDG
                     VFVIKDSTAPSALVPGIEIDGIHIKVDNNMKTSIDGCFAAGDCVGKPYSYIKAAGQGQ
                     IAALNAVYYLDKLKRA"
     gene            32603..32971
                     /locus_tag="JAM15_10095"
     CDS             32603..32971
                     /locus_tag="JAM15_10095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HAT6798603.1"
                     /translation="MENLVKIFKALSDETRLNILILVSKRNICQKGISKYLGISDSAV
                     SQHIKILKDVGIITGYKEGYYVLYHINKESFNICVDFINSMLSNSSESFIDVFDVNTI
                     HLGCSKECKSIKKCCKRREK"
     gene            32974..33345
                     /locus_tag="JAM15_10100"
     CDS             32974..33345
                     /locus_tag="JAM15_10100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HAT6798604.1"
                     /translation="MKVCIPVEENKGLDSKPYGHFGSAPIFVVCDLESGEVKSLDNGD
                     LDHEHGKCQPLKALSGTAVDAVVVGGIGQGAIIKLNGMGIKVYRAEGDTISANLDLLK
                     NGKLVEFPSDHTCSHDGCGHH"
     gene            complement(33489..33944)
                     /locus_tag="JAM15_10105"
     CDS             complement(33489..33944)
                     /locus_tag="JAM15_10105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798605.1"
                     /translation="MNINTVQGDSIEVLLRQLGATRISKVSSTLYFIKFDLGDGWEIS
                     YTYNINAKDQYFLQRIEPYPIGRGLFNDEYEIVSFISKDLKKFLNAKNSSNFKTFVEV
                     TRKVNSIIDNVEELFLNYNVDGDDLKTLNKELNDILNDIDYIEKHTKKI"
     gene            complement(33983..35248)
                     /locus_tag="JAM15_10110"
     CDS             complement(33983..35248)
                     /locus_tag="JAM15_10110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsB/NhaD family transporter"
                     /protein_id="HAT6798606.1"
                     /translation="MEFQQIIAICIFLIVMAAIITEKVNRSVAAVGGALLMIIFNILT
                     LDEGLSHIDFNTIGVLVGMMLFVAVVKNSGLFEYIAIWTAKKAKGDPWKIMICFAIIT
                     AILSAVLDNVTTVLLIGPMTIVITQILGLNPVPFLITQILASNIGGTATLIGDPPNIM
                     IGSAANLSFMDFVINLGPAVIVILAITIICFRFIYGKELVVNERAKNAILKLDEKKSV
                     KDKPLLLKSLILIAFILFGFMFHSTIHIDSSVVALTGASIMLLIGKQDVDEIMAGIEW
                     STILFFMGLFVVVGGLVEVGIINKLAQALIGLTEGHLVFTMLLILWLSAIVSSFLDNI
                     PFVATLIPLILTMQAEGIDVMPLWWATSLGACLGGNGTLIGASANVVLAGIGNKHGHP
                     ISFKEYFKIGFPLMIISIIISTVYLIIKF"
BASE COUNT        13712 a         3808 c         5381 g        12589 t
ORIGIN      
        1 ttagtatgca aaattctatg aagcaggaac cctgtgactt tagtcatggg aggttcagaa
       61 ttacagttta tatattataa taaaataaat tgttaatttt aaaagaggtg aattttatgg
      121 cacatatatg ctttgaggat atttgttatt tgttattaaa agaagcaatg aagttaaagt
      181 taataccaca taataaaatt gtattatttg aagatgattt atcaataggt aatatttctg
      241 atgtaaataa ctacgaatta agagaaaata tttttaagat tagaaatgtt tttgaaaata
      301 atccgaaact attattcaag ccagatttgt tagaagatag gaaattatca aaatgtagaa
      361 atataataat atggtgtgca aataacccaa aagatttgtg tggagtatat tatgtagtga
      421 gtaagtttca agataaaaat ataaagattg cattagtaga tgaaaaaaag acagaagatg
      481 ctctaattag atattcattt accagtgaaa tgtctccaga agattttcca ttctttttag
      541 ataagacact agaaattggc tttaatgaaa aactagaatt taaaaataaa tgggatgtgt
      601 tagttaaaga aaattctatt tttagagcat tagtaggtaa agaaattaaa agtgttgaag
      661 aaacttattt tgataaatat atattaagaa atatcagtga caaatggcaa cctttaattg
      721 aagtggttgc aaactgtatg tttgaagatg aaatgcgtgt aaaagattgg tttatacttt
      781 ggagattaga gaagatggca agtttaaaaa tagtaaaaat aaaaggaagt aaaggggatt
      841 tttattctga taaggagata agaaaagttt aaaaattgaa tttataataa attgtattaa
      901 ataatgggta taactatgaa gaaaaatatc ttaacagtat taatattata attagcaata
      961 agtataatat ttattctata atttgaaaat ataataacta ataccttacg aataagtgtg
     1021 ctaaataaaa aagaaatact tatttcaggg atattagtat atattttaac tacattttta
     1081 cttaatagta ttaaaatatg gtgctataga gtaaataaac tagaaaattt caactttaat
     1141 attacaatag tttattctaa atgccacttc tttagatata ggagatgaaa agcaagtttt
     1201 aatttttttt aatcaataca tgttagatat atcattgtaa attaacataa ctttgaatat
     1261 aataatgttc agaaggcaat atttttgagg tatgaatcca ataatatagt cttatgattg
     1321 tagatatcaa aaaatataag ttactaggaa tacgttttgt agatttatat atgattaata
     1381 actaaagcta taaataaaca aaataaaaag agtatgtttc aacctatagc ttttagattt
     1441 aaaatatact cttttattaa ttatagttgt ataaattaac cctaatatat aattaaaatt
     1501 tttattataa ttatatatta ggttcttcaa ttagttttcc acatacatat ctatgaatga
     1561 tatttctatc atcaccaaca tagataaatc tttcaagtct ttcaagtata gaataattgt
     1621 catgatttaa atttgaatca tcaataatca atgcatcaaa atcataacct tcttcaaagc
     1681 taccaacttt tccaaagaaa cttccaccac ttttggttgc aatataaaaa gcctcagata
     1741 aagataagaa attatacttc ttaccagaat taacccaata taatttagat aattgtattg
     1801 cagataccat tgctttaaat attgacaatg tatgtccacc gcttatatct gatccaagtg
     1861 ctaatctaat attattatcg attaattttc tgataggcat agcaccacta ccaacattaa
     1921 agttagaagc tggacagtga actgccataa cattattttc tctcattaaa tctatttcat
     1981 cctgagaaca atgaacacaa tgagccatta aagtaggagt ttgaccaaat aaattatatc
     2041 tattatatgc atctccatag aatttagatt caggttctag acttctaacc cattcaatct
     2101 catcataatt ttcagataag tgtgattgaa taggaatatt atattttaaa cataaatctc
     2161 ctaaaccttt taaaagttca cttgtacagc ttggtataaa tctaggtgtt attattggtt
     2221 ttacaataga atctgtatca ctatacttat ttataatttc ttctgtatca gtaatagaat
     2281 cctgagtgtt ttctaataaa gtatcagggc aattcatatt catatttact ttaccaacgt
     2341 atgctccaag accaacttct ttgaatatat ccataagttt catagaggct tctttatgta
     2401 ctgttgcaaa cactgctatt cttgtagttc cagatttcca aagttctttt acaaattttt
     2461 tatacatttt tgttgcatat tctatatctt tataatttga ttcttctgga aatgtataag
     2521 tttcaagcca tggcaaaagc tctttatcca tagccattcc aagattttta aattgagagg
     2581 catgggcatg gaggtcattc ataccaggta ttataagctt atcagtgtaa tctactactt
     2641 ttaggttttt gtattcctta ggtatctctt taaatattcc ctttacttta cctttttcca
     2701 gtataatata actattttca aatactgtga aagtttctga agtttttgta aaaattatat
     2761 ttccttttag tacttttaac atataggtct ccttagtttt aaatttgttt taatatatgt
     2821 aggtaaaatt ttgttttaca aatcaaaatt ttaccacatg tattatatca aatctaaact
     2881 ataaatacta ttagataata gcaaatatta gtgaaataca gttgtttact attattatat
     2941 ataactgaca tttaagtgac atttaagaaa aatataatgc ctatttacat aaaatggaat
     3001 gttatttaaa gagaactttg attatatttt cagaagtttt tttatccata tcgtttaaaa
     3061 tatgagaata tctatttata gttattttta tattagtatg tcctaatctt tcagagatga
     3121 tttttatatt agttccagct agaagaagaa ttattagaat agataatata gtaagtattt
     3181 acaaacatgc aggtgttctt aaattgataa attattccat tttaatttta tagtttgaat
     3241 tttatgatat aataaaaata tataaatttt gcagtgagcg atatttttga taaagtaggg
     3301 tttaacagtt gcaatgtaag ggattgaggg tgtatgataa atgttatcaa ttgcactact
     3361 catggttcac tgcaaatttg agagagttgt atgtgtgtaa gtactgaaaa tacttagttt
     3421 attttggggt tttatattaa ctaagtggta tgtaaattat ttttgcgagg atgtgcaact
     3481 aaaattatta ctaagtttta tattaactaa gtggtatgta aatatttaat aaaagtgtct
     3541 atatgggtga aatagtcctt gttttatatt aactaagtgg tatgtaaatc tccctctttg
     3601 aattttgcct taaatataga ataaaggttt tatattaact aagtggtatg taaattaaag
     3661 tttctcacct cgataaaaaa acgtataata agttttatat taactaagtg gtatgtaaat
     3721 cttatggaag ttgtaaatac gacagaccag ggagtaggtt ttatattaac taagtggtat
     3781 gtaaataaca attctattga atgtttcaat tcttctacat catgttttat attaactaag
     3841 tggtatgtaa ataacaaaat gcttaataaa aattcaagaa aactatcttg gttttatatt
     3901 aactaagtgg tatgtaaatt aattttttct tttgtttctt tgtattgttc atacagtgtt
     3961 ttatattaac taagtggtat gtaaattctg aatacggaac ataaatagca acagtaccag
     4021 aatgttttat attaactaag tggtatgtaa ataaaggttt gattaaagat tattcaaaat
     4081 cttttgattg ttttatatta actaagtggt atgtaaatac tcgactgaac atagaaacag
     4141 cttttacaac tccaagtttt atattaacta tgaggtatgt aaatcttata cttagttaga
     4201 actatatatc gacacaaata tgctttatat taactatatg gtatataaat tgcaattttt
     4261 attcgttgtc caatatcttt gaaatttgtt ttatattaac tatgtggtat gtaaatttgc
     4321 aacaagtata ggtaaaatac cccaataatt tatacagcat tttctccttt aaaatataat
     4381 tattttttat catttgtagt aaataattac cagataacat tgactttagt tttaatgatt
     4441 aaaatataaa agtagaataa ttataaaaag tattgaaaaa tttataaata tatataataa
     4501 aacttaatga caagatatta gatataaaaa ataattacct tataaataga ttgaaattta
     4561 tgaatattca tactataatt taaatataag gagatgccct ttgaaaataa aaattaaaaa
     4621 atatttaatg ctattacaat aggaactaga actacactta ataaatatac agaaattaga
     4681 tttggctcaa tataaaatac aaatatagaa tttaggtgtt ttttatgaaa aaaattttat
     4741 atgctttata tagtttcatt gttattatag ctaattttag attaaaagaa aaaaattata
     4801 actttatttt attagcaatc ttttttatac tgctgttaat tcaaaatgga gttttaaaaa
     4861 caggttatca aaatagagct acattttatc aagataatta ttttaatgga gaggataaaa
     4921 atgataagat aaaatttata actataaaga tttttatatt tttgtcatta ccattatgtt
     4981 ttaatatact attcaattat ttaacttctt aaattatatt tagatatagg agtgttatga
     5041 taaaagtaag cttatgtgtt gtttatatta aatataaagt gcatatagtg ataaaacaaa
     5101 agtttcatat aaatgaagaa aaaatataaa ataatttatt taactactta aaaataaact
     5161 aaaagggata ataaaatagc ttttaggtta tggtaataaa ggtatttaaa aagagtgcat
     5221 aagcactcca attgtgagaa atacatacac aaatcattat tacaacaatg aaaaatgtac
     5281 atataagaga cgttttgtat ttgttttaag tgataatatt ttaatactaa ctaaataatt
     5341 atcacaataa taaaaaagaa aaaggagtat tttgtactcc atttgtcaaa aatataaaac
     5401 ttttatataa gcttattata acataattga taaaagtgta aagctatata atgaatttat
     5461 aaagaaaaat aaaataaaaa agataaatcc taatcaaagg atttatcttt ttgtatagaa
     5521 aataattatt ctattattaa atggcatggc taaactggat aataatttat tattactgct
     5581 ttcaatgttt tttctccttg attatggtat gtatgaattg attcagctga aaaacaaata
     5641 gagtcatttt ctctaagttg ataaatagag tcatttactt ctaattttaa ttgaccttct
     5701 ataatcataa tatattcctg tgatttttca gaatgaccaa cagatgtata actatgacct
     5761 tcttctaatt ccatttgaaa taattcgaag tttctagttg gtgtattggg ataataacaa
     5821 taaagacgat aatctttatt ttctgaaact tgtacatcta tatcagtttt tgatacaata
     5881 aaagtttcat tttgaggttg ttccagtatt gcagtatatg gaacatttag tccacttgca
     5941 attttccaaa ttgtgtttac tgttgggttt gagtctccct tttcaatttg cgaaagcatt
     6001 actttactta cgccagataa ttcagcaagt tgacctagac ttaagttacg ttcattacgt
     6061 aatctattta aatttttagc aataacagta ttaatactca tagtaactcc ttaaaatgta
     6121 aattattgac aaatataatt tacgaatgta taatttattt aacattattt ataatttaca
     6181 aatgtataat ataatgaacg ttaaatacac tgtacatccg taatataaat tatactgcat
     6241 aaagagttgt ttttcaacgg atgatagttg agagattaag ggggaattgt aatgcgtgta
     6301 cttaataatg ttacagaggc tataggcaat actcatatgt tacatttatc caaaatagca
     6361 gatgaatttg gagttcaagg taatatttat gcaaagatgg aatacttaaa tccgggattt
     6421 agtaaaaagg accgtgtagc attacaaatg attaccgaag cagaaaatgc aggtttatta
     6481 gttccaggtc aagcagttgt ggaattaaca agtggtaata ctggaacagg actagcaata
     6541 gcttgtgcat gtaaaggata taaatttata gcgtgtatgt caaaaggaaa ttctatggaa
     6601 agagcaagaa tgatgaaagc tttaggtgct gaagtagttc ttgtagacca aatgcctaat
     6661 tcagttcatg gacaggtatc tggtgaagat ttggcacttg tagaaattga ggctcaaaaa
     6721 atagcaaaag aaagaaatgc atttagagca gaccaattta atttagaagc ttgtaatcat
     6781 gcacatgaaa agtatacagc agaagaaatg tgggaacaat tggatggaaa tattgatgta
     6841 tttgtagatt ttcttggaag tggtagtact tttgcaggat gttcaaaaac acttaaaaaa
     6901 cataattctt ctatcaaatg ttatgttgtt gaacctgaaa cagcagcaat ttattcaggt
     6961 aaagaaataa ctgaccaagg gcataaaata caaggtggag gatattctat ggatttgcca
     7021 ttagtagaca agaaacttat tgatggttat attcaagtta cagatgagga ggcaactgat
     7081 gtagcaagaa aattagctaa attagaaggt gtatttgcag gattttcttc aggggcaaat
     7141 gtatgtgcag caattaagtt gttaaagagc agtgaaaaag gaaaaaatat agttttaact
     7201 cttaatgata gtggtttaaa atatttaagt actgatttat atgaagaatt gtaataatag
     7261 cacaatagtt atgcaatgtt ttttaaatta agtatataga tttaaattat aaaaagtatc
     7321 tcaatgtgat ttttgaaagt tataaaagag atactttttt attttgtaaa tatggagtat
     7381 cctacttata agtattaagc tatatagata ttgatgatta gctatgcaat aaaaaagagt
     7441 atgtgttttt gcatttatac atcataactt ggaataatac atattaatgt tctaaatgta
     7501 tttaaaacat atgataaaat tagaacaaac agatacaagg agataaacat gcaaaagaga
     7561 attttaagaa attttatatt tacgggtaaa aatattttaa gtaaacttgt ttttataata
     7621 aaatataatt ttagtacatt aattttattt gaattatttc ataaaggatt agccttattt
     7681 tttatatggc catctattag atatatattt gatattttaa taaaaagttt acatatagtc
     7741 tacctaaata tggataattt tataaaagtt ttgaccaatc ccatgtcaat agttctgata
     7801 atactatcag ttataatact agctttttat gcattttttg aatttacctc tgtaattatt
     7861 tgttttaata aatcgataaa atatgaaaaa atagggttat ttgaactctt taaaatatca
     7921 tttaagaact ctataaaatt gttatatcct aaaaatatac tattatttat atttgtgata
     7981 ttaataattc cattagtaaa tacagtttta atttcagggt ttataggaaa aatacaaata
     8041 ccagagtaca tactagatta tataaagtct gatataattt taaatataat ttatatgatt
     8101 tttcttttaa taatatatat ttcggttatt agatggattt ttagcattca tgagataact
     8161 ttaaatacag aaaattttaa aagagcaaga aaagaaagtg ttaatcttat aaagggaaag
     8221 attataagaa caattattta ttcattaata ttatctttag tagtagctat tattggatat
     8281 gcgatttatc atagtggaat tatatttata ggcatatgga ctaaatattg tactgatatg
     8341 gaatttttga agaatgtatt tataaataga tgtattgcat ttgaagaata ttttagattg
     8401 attttatcaa tattcatttt tatattggac attggattta tctcagcaac ttattatcaa
     8461 tataaaggag taagtatttc taaaaataat attaaaaaag agaaaaaatc tatatcaaaa
     8521 attgttttta atttagtatt aatattatta atttcttata tagagtcagt tgcattttct
     8581 tcacatataa atggtatgtt taatacgtca ttttcatttt atacaacagc aattgctcat
     8641 agagcaggag ctgaaatggc tccagagaat actttggcag caatagaaga agcttcacat
     8701 gctaaagctg attatgcaga aatagatgtt caagaaacta aagatggaga acttattgta
     8761 cttcatgatt caaactttaa gagaactaca ggagtagata aaaatgtttg ggatgtaaat
     8821 tataatgaag taaagaccta tgatgcggga agtttttatt attatggaaa aggttattat
     8881 gatgaaaagt ttgttgggga aaagatacca acactcaaag aaatgataaa atattctaaa
     8941 ggtaaggtga aattattaat agaaataaaa tttaatggac atgaaaaggg agacgtagta
     9001 aaaaaagttg ttcagttaat taaagaaaat aattttgaaa atcaatgtat agttgcatct
     9061 atggataaaa ctatattaca aaaagtaaaa aaactggatg agaatttact gacatgctat
     9121 tttatggcaa ttgcatatgg tgatttttca aagttaaatt atgttgatat atatggaatt
     9181 gaatcaactt ttgttaataa aacagtagta gaaaagattc ataaaatgaa caaaaaaatc
     9241 ttcgtttgga ctgttaatag tgacagttta attgagaaaa tgcttgacct aaatgtagat
     9301 agtattatta cagataatcc ataccttata gagagtgcaa tttattggaa gaaaaatgga
     9361 tttattagtc aagtgtcaga ttatttattt taaatattct ataattgtat tatccagtaa
     9421 aagagatatt attaaaatca ataatatcta tttttaacat aaataaggtt gttaaattaa
     9481 ggttattctt ataaaaattg tgcttatcag ctataaacaa ggaataaaag tgaaaaaatt
     9541 gctctgagat tattacagtt aaaagagttt taagatgaca gagagataga ttgtcaactg
     9601 tatatttaat aaatcttgtt atttattaaa ttttatataa gtaaaatata taaattaata
     9661 aatcttaggc tagaatatat atgaaaaaca atataaattt ggaggattaa aaacatgaca
     9721 gagcgagaaa aaatgttggc aggagaactt tacgattgtg gtgatattga gttgttaact
     9781 caatggcata aagcaaaaga cctagtaaga gattataacc aaacagattc ctcggagttg
     9841 gaaaaaaaag aaaaaatatt aaatgaatta cttggtggta aaggtaaaaa tttatggatt
     9901 actgcaccgt attatgtcga ttatggaaat aatatttatt ttggaaataa ttgtgaagtc
     9961 aatatgaatt gtacgttttt agatgataat aaaattatca ttggggataa tgcactaatc
    10021 gcaccaaacg tacaaatata tactgcattt catccaacta atgctggtga tagatttggt
    10081 aatgccaaag aagatggttc atttgaattt tgtaaaactc aaacagctcc agttactatt
    10141 ggagataatg tttggattgg cgggggtgct attatcatgc caggtgttac tattggagat
    10201 aatgtagtta taggtgcagg aagtattgtt acaaaagata tttcaagtaa tatgattgca
    10261 tacggaaatc catgccgtat tattcgagaa aacaaataaa gttaaatttt cttgcaaaat
    10321 ctcaaaaaac acctttctta ctttatatat aggtattttc caatactttc acatccatat
    10381 tcatttgtta aatttttgtg gaatgtagtt tttatcactt ctatcttaca tttccaccat
    10441 tttttataaa agtcattcct ttatagattt atttataata gtatatattc tatttgatgt
    10501 ttgaataagc acttattttt aagtaaaata ctaactttta ggttagtatt ttgctatagt
    10561 atgatgatta agtaagaata aaatactata atacataaag cttaataaat ataattttta
    10621 ttttacttag atattttctt ttgattagca atcaaaagtg gttataattt ttttaattaa
    10681 taagagtaac atttatttta tgaaagagga ttatattaat atatatttaa ataggaaaaa
    10741 ttgtaaaaag cataaaaata atataattaa ttaatgagat aaaagtggat aaaaatattg
    10801 gtagtttaat ttttgtgaaa ttaaaaatat taaagctaat ctacaaatat agaatatatt
    10861 ctaagacgaa tttttataat tactaaataa aataaattaa tcaatatagt tttttaatat
    10921 aaacaaaaaa taaaaaactt atataaataa aatgcttgtt tttcttgtat tatttatata
    10981 aatattgaaa tttgtctagt tatacgtttt tattgaccag ttatgcagtt gatattgaat
    11041 attctaaata ttggtgttat tttataggtg gtttaaacat attaggggga ttttatatat
    11101 gatttgtatg atttatagag aatgtataaa atagtaaagg tttagagcat gtttagtgga
    11161 ttgcagaata tgcatataga atgattcttg taaattaagt tagacatagg aaatatataa
    11221 tttgtattgg atgattgatt ttatggtgta tgcttttaac ttctataatg ggaaagtaaa
    11281 gatgtactcc caatacatct ttactttagc agaagttata gttacttata aagtacaaaa
    11341 aattatatat ttattagagt agataaatct aaaaaggttt ttctagaaaa atttagtttt
    11401 aattgtatct acttactaat aataagactt gatgtaagca ggtttcaact accgtttctc
    11461 catattctga tataaaatca tctaactgtg tatctaaaaa attacaataa tcatatgaac
    11521 tactgatgta agcagttagt atatgtgtac atttgtctat ttctccaata aacatattat
    11581 ccatccccct aaaaaattta gtaaaaataa aaagtcgcat tctattagtc aattaacata
    11641 atttataaaa ttttttagta ctagtttcta taacttaact ccttaaggtt aaatattccc
    11701 agttttacca atttagtttt attctacaag tatataatac tagaagatgc ttcattattc
    11761 aacatgcttg tttgagaata gaaaatattc taaaattata attgttttta aaaataagat
    11821 tcaagataaa taaagttata tgcaactatt taataatctt tccataataa gaacagtagg
    11881 ttctattctt aaaaaactcc atctttaaat ttaaagaata actacaattt gaacaacaat
    11941 aaaatttcca atcaataaaa atatcaaaaa taataaaaat aataaaaata attgaaaatg
    12001 tataatttcc cagaaaaata ataaatgtaa ctccaataat aaacacacct ataaattata
    12061 aaataattta agctttattt aaggttagta ttatatttat ataagattta agttttaata
    12121 tatatgtgta attaaaatga tttaggagga gaaatatatt ggtaaattgg gaaataaaaa
    12181 aattggctaa atctaagagt atgtttatat ctctagggat attagtgtta atactaatga
    12241 ttagtatctt tattacgcct gttttagaaa cagaaagtta ttatatagat aaagaaaaag
    12301 gacgtataga agatacgaga agtggtatcg acataggtaa tgagaaattt caaaataaga
    12361 ttaatgtttt aaagcagttt tcaaatcaaa cagatacagg tgaattttct aaaaaaattg
    12421 aattaatgtc aaagaaaaaa cttgataatc taagtgtgaa tgaatataag gatattagtt
    12481 tttggaaagt atttaactat agagttacaa attcacttat aaatgtagga atgttaatca
    12541 ttatatctat aattatatcc aatatttacg tagatgaagt cgttacttcg gtaaaagata
    12601 tcatactatc atcaaaagag aagaaaaaag cattaaagtc taaaatattt gttgctttat
    12661 tagttccatt agtaatttat tttgtttatt taatgggaat atttattata acttgtatgc
    12721 aacaaggagt acctgttaat ggagacttag aatcttttag aatagtagac aatgtagttg
    12781 cattgaaaac taatttaagt ataacaaagt atgtaatatt aaatataggc atagagcttt
    12841 tgatgtttga aggatgggcc atgatagcca tatttgggtc ttttataagt aaatcttcaa
    12901 tatcttcaat aagttttttt atatttatta tatctataac taagataatg tcggtagtcc
    12961 atatattacc taaaaaatta ctttcagttg tatcaaatgt aaattattat gatttgatat
    13021 ttggttttaa taaaataata ggaaattatc taggtgatat tatgatattt aaagtgaata
    13081 tagacattgt caatatagca ataggacttt tgatggcaat attgataggt gttatgtcat
    13141 tatgtttttt agtaataaaa tcagattata taagtagata aaaggggaat taagatgaat
    13201 aaattagaaa tagaaaatct ttcaaagata tatggtaaaa aagtagcaaa cgacaagatt
    13261 acagtaactc tggaaaatgg agtttatggt cttctaggac caaatggagc aggaaaatct
    13321 acattaatga aacaaataac aacgttgata aaacctgatg aaggtcagat actttataat
    13381 ggtgaggata tatttaaaat ggatgctgat tatagaaata ttttaggata tttgccacaa
    13441 gaatttggag tttataaaaa ttttacagca aaagaatttt tacagtatat tggagcttta
    13501 aaaggtttaa ggggaaaata tttaaatagt aagataggag aattattaga tttagtaggt
    13561 ctttacgatg tgagaaataa gtctatagga aaattttcag gaggtatgaa gaggagagtt
    13621 gggatagcac aagttttact aaacgaccct aagataatag tccttgatga accaacagca
    13681 ggtcttgacc cacaagaaag agctagattt aggaatttaa tagcaaaaat gtctagagat
    13741 aagataataa tactttctac tcatataatt tccgatatag aatcagttgc aaaggaaaca
    13801 ataatgatta aagatggcaa acttctaatg aaaggaacac acaaagacat attaagtcac
    13861 atggaaaata aagtatataa tgttcaagtt aaaaatgaat gtgaagttga tgatatacaa
    13921 tctaaatata aggttgtaag tattcaaagt gatattgatt cagtagtact tagaattgtt
    13981 tcagaggata ttccaagtgg ggataatata caaccagttc aagcaaaatt cgaagatgta
    14041 tacatgtttt attttgattt ggaagatgca agggaggtgt agtagaaatg atgtatttag
    14101 ttaaagctga aatgataaaa atattaaaat caaagagtgt ttggataatt tggctgtttt
    14161 taatattttt tggatttctt ctgattagaa agtttgatgt tttagatact tatgcagata
    14221 tattttacaa gatagaaggc tcaatacctc taataggttt gataatgttt ataataactt
    14281 ctggaaatta cattaaagaa tatgattcta atatgacagg tttaataaat acaactaaaa
    14341 agggaaaaaa atcagtagta ttatcaaaac tagtagctaa tggattaatt ttatctatta
    14401 ttaatatttc ttttatattg ttagtaggaa ttagaggttt tagttttttt gattttaaaa
    14461 atttaaatga accgattcat aacttatggt actttggaaa tagtaattta aatcttacag
    14521 taatacaaat gtatataatt gttatattga ctactatttt tgcttctttt atatttgcac
    14581 aaataggctt aacactttca tctatattta aatcggctgt aattccattt atactaggtg
    14641 gattgataat ggcaattcca tactttagtg taggttttat accagataaa gctataaaat
    14701 ttatgtcagt gactccaaat tggattatga tgagccaaca aatggttagg tataatgtac
    14761 caagtatttt gatagttttt tctatagtaa tctcaattat attaatgata gtgttaacta
    14821 aaataacata tgaaaatttt acatcaagca aaaggtttta actaaaaata atagtaattt
    14881 tatttatatt ttagtttaat taaaaataag ataaatgaat tttagataaa atatatgcta
    14941 atatatatgt aaattattac aggaggttgt ttatggaaaa tcgtgtttta ataatagatg
    15001 atgaagtaga aatattgaag cttttagaaa ctgtcctaaa aaaagagggc cttaataata
    15061 tatatactgc aaaaactaaa aaagaaggat tagaattatt taaaagtatt aatcctgatt
    15121 tgattgtatt ggatattatg ttaccagatg gcgaaggtta tgatatttgt aaagaaataa
    15181 gaaaaacctc caattctcca ataatatttt tatcagctaa aaccgaagaa ttagataagt
    15241 tacttggact agcgattgga ggagatgatt atgttacaaa accttttagc cctaaggaag
    15301 tggcttttag agttaaagcg catttgagaa gattaagtta ttttagtgat gttcaaaacg
    15361 aaagtaaaaa tctaaataag aatgaagaaa aaattatatc atttggccca tatatattaa
    15421 atgaaagtag ggcagaactt ataaaagatg gaaaatctat aggactgtct gcaaaggaac
    15481 taaaaatcct atctttattt gcacataatc aaaatcaaat tataagtaaa gaaaaactat
    15541 gggataaagt gtggggagaa gattatgttg gatttgacaa tactataatg gttcatataa
    15601 gaaaaattag ggaaaaatta gaggataatc cttcaaagcc tgaatatatt ctgacaataa
    15661 aaggtcttgg atataaatta gcagtaaagg aagattagaa tatgaagtgg aagattacta
    15721 gaaattttat atttacaatt gtgtttgtag ctatatcagt agtaattata aatattatat
    15781 ctatattgta tgtgatttca actaatagct tttttaaagt tgtagattct ggaaataatc
    15841 ctgaagaatt tgcacgttct tttgaaaaag atttatatga aaaagatgga gaatttaaac
    15901 tatctaagat tggagctgaa aaattagaaa aatcaaattc ctggatacag gttttaaatg
    15961 atttaggaga ggaagtttat ggagtaaatg tgccaaagga tactccaaaa aaatatacac
    16021 cctttcaaat ggtgaataat tacaagtata tagaaacaaa gtatgttaat tttgtactag
    16081 aaaaatattt aaacaaaaaa catctaaaca taatagtagg tatacctagt agagatatat
    16141 caagaataat tttaacctat tctcaaaata acattaaaaa aactttaaat aaagttatca
    16201 ttataacact agtaattgat agcgtggtag ctttaggtgt aggatattta tttagtagaa
    16261 aacttacaaa accaatttca agcatactat ggagtattga gactatggct aatggaaatt
    16321 atagtttata tcttaaggac agaggtatat atgaagaagt ttttaaaaat ataaatatgt
    16381 tagctgatac tttaagagta aatgaagttg agagaaaaga aaatgaagag ttgagagagg
    16441 aatggctggc aaatataaca catgatataa agacacctct agcatctata caagggtatg
    16501 cagagataat taatgacaaa gattatgagt ttgaagaaga tgaaatacga gagtatacag
    16561 aaattatata taataagtct aagtatataa aagatttagt tgatgattta aatttatcta
    16621 ctcgattaaa aaataatact atagttctgg acaagaaaaa aataaattta gtcagtttag
    16681 tcagagatat aataattgat attttaaatg ataatagata taaaaatagg aatattgaat
    16741 ttgaaagtaa tgaagattta attgaagtat atgtagattc aatcttattc agaagggcta
    16801 taaccaatct tatatttaat tcaatagttc ataatagcga aggaactttg ataagtgtag
    16861 aaattgtaaa aaaagataat atagaaatta taataaaaga taatggaatt ggaataagca
    16921 aaagtgattt gaaacatatt tttaaaaaat attatagagg tactaataca ggtgagatgc
    16981 ataaaggttc aggtcttggt atggctattt ctaaagaaat aatagagatt cataaaggta
    17041 aaatttatgt aagtagtgaa attggaatag gaacaaaaat tattatagag ataaaacaaa
    17101 attaggagat atgatatgga tttttttaaa aaaggtataa gtgggtttac tattaagatt
    17161 ttagcattaa tatttatgac atttgaccat atagcagcat ttatgccaca aacaatgcaa
    17221 ataccaattt ggtttcattg ggtaggcaga atatcagcac cactgtttat attcatggct
    17281 gttgaaggat tttatcacac tagtaacaga aaaaaatata taagtagatt gtatatttgg
    17341 tctgttatta tggctatagg aaatcaaata attaataatg tattttcaca tccagaagga
    17401 gctataatta taaataacat tttttcaaca ttatttttaa tagcgattta tttacaagca
    17461 atagagttca taaagaaatt tagaaaagag aaagaaatta aatattttat tataggatta
    17521 ttgatgataa tcattcctat aattttagga atatttacag tagctttact ttttaaagtc
    17581 actaacagag ttattacttt atttatgatt ttggtaccag taccattttt agtagaaggt
    17641 ggaccaattt ggattatact tgggattatt ttttatttgt gtagaggtaa aaagttcagt
    17701 ttgagtattt gttatgtttt gatgtgtata tttatattta caacaatgtc aaatggagat
    17761 tatagtttaa aaaattctat tttacaaaat taccaatgga tgatgattgc ttctctacct
    17821 ttaatgttac tttacaatgg agaaaaaggg aagagtatga agtatttatt ttatttatac
    17881 tatccaatcc atgtatatat attgtatatc ttaggaatat acttaataaa tggtttttga
    17941 ttgtaagtga tatttttaat acaaaatgaa caatatgagg attgttttag gtctattaaa
    18001 attgttattt agatgagatt tgtagaatat ttaaatttat gagcagaaat tcagttattg
    18061 taatttcaat aacattagaa tataatatta taatttattt agaaatatat gatgttatat
    18121 atggtttggt tattaatgta ataataaaac agaggtttga tataaaattc aatacctctg
    18181 ttttagtgtt ttttatccta tatttatgct tattttattt ataaattagt gttttgtttt
    18241 aattaatatt agtgcatttt ttatttattt tataaaatta gtcataattg tttcttcata
    18301 ttgtggttct ttaattccag cttttttacc tgctgatata cacttaagaa gccatgccat
    18361 gttttctcct agagttcgca tagtctgtaa tccttcttca tccttcataa catcctctgg
    18421 agtaaagcca tgtacctgat tccaatactg tgatgataca ataggcatat tgctgattga
    18481 aaaatattta tttagttggt caaatgttgc acttgcacca ccacgtctac atgacacgac
    18541 tgaagcacct aattttgtag ccatgcgact tccagctatg aaaaatagac ggtcaagaaa
    18601 agaagttaat tgaccagttg cactagaaaa gtaaacagga gaaccaataa taataccatc
    18661 aatattatcc agatcttcaa tcaattcatt aactttatca tttcgaatac attttccagt
    18721 ttcaaaacag gatgcgcaac taatacatcc tgggattgct tctttaccta aatacagtat
    18781 ttctgtttta atatcgtgtt tactcaatac tttagtaatc tcatttagtg ctgtataagt
    18841 acatccatat tggtttgggc taccgtttat caataaaact ttcattataa atttcctcca
    18901 atgaatttta tttaatagat tttctaagag atattatttt ttataaaata ggattttcat
    18961 gaatattatc aatttatata gaaatgtcta atcttagaat cctatttaaa ataactcttt
    19021 ttttagtaaa tacacctcct attataaaat tgactttcaa ttattcttac actataattt
    19081 tattataaat tattctaaaa acaagtacgc acatttttgt tcaatactaa ccaaaaggag
    19141 agtgtaatat atgagtatag actgtatatc aaatacagat ttaagtgaaa caggatttag
    19201 ttatacactt tcactgatta gtggtaaata taagatgata attctttact gtcttgtaga
    19261 atttgaagtt gtaagatata atgcattaaa acgttatata aatactattt cctataaaac
    19321 tttgagttta tcattaaaag aattagaagc agataacttg attattcgta ctgaatatcc
    19381 tcaaatacct cctaaggtag aatatagttt atcagaaagg ggaaaatctc tgattccaat
    19441 tttagatgca atgtgtgagt ggggagagag gaatagacct taattttgca tctgcagata
    19501 ccataaaaag actgtgagta aaattgtttg aataatctac tcacagtcta tatttaaatt
    19561 aatagttagt atttttaatt tataagaata ctaaaaaatt tattatgaaa tttcaccacc
    19621 aatttctttt acatcttctt tatatataat acaagcttct atagctaatt ctaagccttt
    19681 tactatttct tctaaagaca tgaatggtgt atttttttta tctattactt gtgaagttgt
    19741 atatgggatg tgtataaatc caccccttat attaggatat ttcttgtcta tcatataaag
    19801 gattccatac atcacatgat tacaaacgaa tgttcctgca gtgtttgaaa cactagctgg
    19861 aattttattt tcattcatat gttttaccat ggcttttaca ggtaattttg aaaaatatgc
    19921 aggttcacca tcttctttta taacagtatc tataacctgg ttaccttcat tatcttttat
    19981 tctaaaatca tctatattta tagcaactct ctcaggtgta atgtcaaatc tacctccagc
    20041 ttgtccaact gatattacta tatctggatt gtgctcttga atagctttat ctatagcttc
    20101 aacagatttt gtcataactg ttggtatagt tatctttatg atttctgcac cgtttatatt
    20161 attattgacc ctttcaactg cttcttgagc tgggtttatt agttctcccc caaatgggtc
    20221 aaatcctgtt aacaaaattt tcattatttt acctcctaat tatattaaaa tcctaaaaag
    20281 tacattacta atatgtgggc tataattaat accaaagcaa ctggagcttg atattttata
    20341 acaatataat catttttaca ttctagcaag gctgctggaa ctatattaaa attagcagcc
    20401 attggagtaa gtagagttcc acaatatcct gctgttaatg ctaatgctcc aattatagca
    20461 ggatttccac cttgagacaa tacaaaagga ataccaattc ctgccgttat gactgaaaat
    20521 gcggcaaatg catttcccat tatcatggta aatataacca tacctaatac ataagctata
    20581 acaccaaata atctgctatc agcagggact acaccagata tcatggttga aataacttcg
    20641 ccgactccag cctgagtaaa taaagctcct aatgcaacta aaagttgtgg taacatacta
    20701 gcaggtccca tttgttgaag taatcttgag ccatcttgaa ctgatgtagc aggttttgct
    20761 ttagttatta taagggctga tattaatgca attattgaac ccacacctat tgcaaattga
    20821 gaagaattat caaaattaga aaggctcata gctactacta ctgcagcaaa tgctaatatt
    20881 aatgatggta taaatatttt atttttaagt ttgtctgctt gttcttttcc aaaattttca
    20941 tctggttctt catactttgc aaatacaact tgtttagaaa gtgttaataa actagataat
    21001 attaatatta ttcctattat attggctgga atcaatctac caaatatgaa tggcagtgat
    21061 ataagtatcc aaaataatga tgtaccatat ttcttattgt tatttatggt agtaaaagac
    21121 ttatatgcta taacaatcat taaaaatccc attagtgcgt aaaagatttc caatgatatg
    21181 tttataaaat tttgcatttt tattcctcct aaataaaact attttttatg acttttgttt
    21241 aattttttat catataaggt aaactggatt gtagccacta caagtgctat tactgccata
    21301 atagtactag cctttacaat attaagtcca gttacattgt atccaaattg agttagagta
    21361 gatgctataa gtaatactcc actactacct gcaaataagt tttgaccata aaaatttcca
    21421 tagttttctg atgcagcaga taatgccttt atggcttctt catccgattc ttttagttca
    21481 tcactattac ttaaaccagc agcttgtgcc ataggattaa caagtggtct tacaaattga
    21541 ggatgtccac tcattcttat tgatagagca ccagctattt gtctagctat catgtatata
    21601 gtaagtactt ttcctgttgt aagtcttttt aatttttcta ttaaagaaac agctctttgt
    21661 tttaaaccat atctttctaa tacaccgatt actggcagtg ttaatatgaa taatgataca
    21721 cctctgtttg agacaaaaga atctcctaaa attgtaaaaa tttgattaaa atctaatcct
    21781 gcaacaattc ctgttgccac tcctgctaat aatacagtaa ataatgtgtc aattttaagt
    21841 ataaatccaa ttacaactat caatataccg attagtttta tcataaattg ttctccttcc
    21901 atttctatat gttttaattt aaatttattt aatggataaa gttaaactct ttttatagta
    21961 tttgcgttaa taggactatt attataaaat ttaagaaaaa atagggaaga tgttttaaag
    22021 tatcaaagta aataatggtt gtgtatagga atttgagtaa caaagattat attttaagct
    22081 aatatgaatt gattttgtaa gtctatggtt taagtatatg tcaatatttg aaataggttt
    22141 taaattagat attatattat aaaaagagaa tgtgtcaaac atagagacaa gtgtattttt
    22201 ctctgttgaa atgataaaaa tatatttgat ttcatacaaa aagagagtgt ctaatgaatt
    22261 ttttagttca ttagacactc tctttttgtt atgattaata aagcatatat taagttctag
    22321 tttcattaga tttcactaag aaaaataaaa ttttgataaa gtttaaagac tattttgagc
    22381 aatattactt ataaataaaa gaatttatca tagaaataat tagttttatt ttagctatta
    22441 agatttatta aaaaattatc tatattatcc tgtgatattc taaaactgtc ataattacct
    22501 tttgaaacag ccttcataat aagtttatct aaaaatttca ttttttctaa tcgagcttca
    22561 ctaccaaaaa ttccaatagc atttgcactt tctaataagg atgatggaaa atttgatttt
    22621 aaatatttat ctgcttgttc agaaaagcca cagcaaagga aaatgccaac ttgttttttg
    22681 tttaataact ctacattatc attacatagc acttgtattt tttttgaaac tgaaccaaca
    22741 tatatagaac ttccaataat aattttatca aattttgata actcaatttt attattatta
    22801 ttattaatat caacaatagt gacattatct gatagtttat tttttagtat atttgcacag
    22861 tcttttgtac aaccatattt acttgaatat ataataatag tattcataat tattctccct
    22921 ttcttaaagc attttctaca gcttttcgta tagtattact gctataagtt gcagaagtta
    22981 tagcatccac atctaaagac tgttgtttaa taatacttgt tgtaattttt tcagcaggtt
    23041 tacctaaaag atggtcgtgt tttaagatat taatattttg gattttacca ttattaactt
    23101 caacagacac agtagctttt accaagttat tatcagcact tccagtataa atgccatttt
    23161 taacattatt aatatctata tcttttacta ccaagttttc tggctttaag ttgcttacaa
    23221 ttacaataat aatgcatata aatacaaaga atagagcaat agatattttt acatattttt
    23281 tctttttatt agtagctttg ttgcgaattt tcattgtaaa gtcctcccac taaaatatct
    23341 aagaaatttt ctataagttg agaaaaatta tgtaaagaat atagtttatt ttcaacaaca
    23401 cataaaacga atcctaacaa tgcacttata agcatccatg agcttttatc tatatttttt
    23461 ttgaatattc cttgttcaat tccaatggaa aggaatttat caagcatttt tataccatta
    23521 ttgctaggag tattgtttgt attttcagat gcaaatataa tattcattct actatgcatg
    23581 atagcttttg ccatctctgg ttcactagaa agagttttta taaagctagt cataatttct
    23641 atgatttgtt tatctattgg tagtgatgag caattattca taatgtcaat agcattactt
    23701 tctactgtgt tataaagttt attggtcata tcgctgataa tctctgcttt gtccttgtag
    23761 taaagataaa ttgtagttgg agaatattct atttttgtag caatttttct tattgataaa
    23821 ttttcatatc catgttggtt tataatttcg atgctagcat ccataatctt tttcttcatt
    23881 tcttcttttt catttttacg tctttctttg atactcatat aatcacctct ttgcttaacg
    23941 gtgttaagtt aatttacact gttattgtat aatttaattt taatactgtc aataaattat
    24001 taaataatat aagttaatat atttttatgg ataataaatt aatgttatta attgtaatat
    24061 ttaagatatt attgtataat aataatcggt ttaaatgcgc cacatcttat taaagttggt
    24121 tcataattct aaataaactt taataagata cattaaaata taataaattc ttttatgcta
    24181 taaaatttat tttatagcta ttaaatcaga tgtttaaaaa ttttttaaca gtctatagtt
    24241 tttaagagtc tatagtaagt agcctaaaaa tatgatttta catctgtact tgttcgagaa
    24301 ctccaagtat aaaaaactaa ggaattatat agtggcagta tataattaat acccttagac
    24361 acaccttttt gaaagtggaa aaaagatgtg tagttctcct cgaccacaaa tcaaggagga
    24421 taaaaaatgg aaaagagaaa agtaataatt gattgtgacc caggaattga tgattctttg
    24481 gcaattcttc tggctttaaa ctcaccagag ctagaagtaa ttggaattac cacatgttgt
    24541 ggaaatgttc cagcaaatat aggtgcagaa aatgcactaa aaacacttca aatgtgttct
    24601 tcactaaata ttccagtata tataggagaa gaagcaccac taaaaagaaa acttgtaaca
    24661 gctcaagata cacatggaga agatggtatt ggagaaaact tttatcaaaa ggttgtagga
    24721 gctaaagcaa aaaatggagc agtggatttt ataataaata ctttacataa tcatgaaaaa
    24781 gtatcaataa tagcacttgc accacttaca aatatagcta aagcacttat taaagataag
    24841 aaagcatttg aaaatctcga tgagtttgta tctatgggag gagcatttag gattcatgga
    24901 aattgctctc cagtagcaga gtttaattat tgggtagacc cacatggagc agattatgtt
    24961 tacaagaatt tatctaaaaa aatccacatg gtaggtttag atgtaactag aaaaattgta
    25021 cttactccta atattattga gtttataaat agacttgata agaagatggc aaagtatata
    25081 actgaaataa ctagatttta tattgatttc cattgggaac aggaaggaat aattggctgt
    25141 gtgataaatg accctctagc agtagcgtac tttatagaca gaagtatatg taaaggattt
    25201 gaatcatatg tagaagttgt agaagatgga atagctatgg gtcagtctat agtggattct
    25261 ttcaatttct ataaaaaaaa tcctaatgca attgttctaa atgaagttga tgagaagaaa
    25321 tttatgtaca tgtttttaaa gaggcttttt aaaggttatg aagacattat agactctgtg
    25381 gaaggagtga tatagtgtga aaagaaaaat atgtgtaaaa actattacac ttatagcttt
    25441 tggtatttct ataaatataa taggcgcttt tatagctatg ggattaagat tacctgtata
    25501 cttagattca ataggaacta taatgatagc ttcactttta ggacctaaat acgctgttgt
    25561 tacaggtgtg tttggaagtt taataagtgg aattacgttt gatgtgtatt ctctctattt
    25621 tgcaccagtt caaatatcaa ccggattact tgctggaata gcatttaaaa agaatttttt
    25681 aaggggttta aaaactccac taggagtact tttatttgct attccaacat ctataataag
    25741 ttcaataatt tcagcatttt tatttggagg tatgacctct tcaggttcat cctatatagt
    25801 gcaaatcttg aaagtgttag gactgggaga tgtttttagt gtgtttgtaa cccaagtatt
    25861 tactgattat ggagataagc tgttagcagt tgttttagtg aatttaggat taaatgcagt
    25921 tccaaaaact ttaaaggtat cattgactgg aggaaaatag atagaaaatg gatagatata
    25981 gtgagataac aaataaaaat caaagagaaa ttgttctgct taaaggattt ccttgtatat
    26041 ggggaaagtg ttctttttgt gattatatag atgataattc taatttagaa gaagagatga
    26101 ataaattaaa tctaagggtt ttaaaaaatg taactgggaa atatggagtt cttgaagtca
    26161 taaattctgg aagctgtttt gaattaccta aggatacttt agaaaaaata aagtgtatta
    26221 taaaagagaa gaatataaaa aaattatttt tagaaagtca ttggtcttac aaaaataggc
    26281 ttaaggaaat gagagagtat tttgaaattc ctgtggtatt taaaattgga gttgaaacct
    26341 ttgacaatga ttttagaaat aatattttaa ataaaaatgc aaattttaag actccacaag
    26401 atgtaaaaga atattttgat tcaccttgta ttatggttgg aataaaagga caaacaaaag
    26461 agatgataga taaagatata gagattatcc taaatacttt tgaaaaagcg acagtgaatg
    26521 tttttataaa taattcttct agtataaaaa gagatgaaga gttagtgaaa tggtttgtta
    26581 gtaagtataa attcttggat gaaaatccaa atatagaagt tttatacaat aatacagact
    26641 ttggtgtagg agattagcat taatttagtt taaatttaaa attgaaaagt ttcttatgtt
    26701 tttgaaaaag cttctaatag ttagaagctt tttttgtaga gttttatgtt acaataagaa
    26761 aaaaggaatt aaggagcaat taaatgatgt ttgatagggg aaaatggaat aaattggatt
    26821 ataatgaact tttagaatat atgatgtcta taaaagatat aaaatataga gattttaata
    26881 aaaagcttat acctggaaca gaaaatataa taggtattag agttcctaat ttaagaaagt
    26941 tatcaaaaga aataagccaa gggaattgga aggaattttt agaagtagca gaggatacat
    27001 actatgaaga agttaggcta caaggtatgg taattggcaa tataaatagt aattttgaag
    27061 aaactttata ctatgtaaaa agatttatac ctaaaatcga taattggtca gtttgcgatg
    27121 ggttttgttc tggtttaaag tctatgaaaa aatataaaga aaatatgtat gatatactta
    27181 aaaaatatgt ttattcaaag aatccatggg aaattagatt tgcattagtt atgtttttaa
    27241 tatattatgt tgatgataaa catattaaag aaatatttga atactgtaat aatatacaaa
    27301 gtgaagaata ttatgttaaa atgggtatgg catggttgct atcaatttgt tttattaaat
    27361 gtgaagagga aacttttctc tatataaaaa ataataattt agatgatttc acttataata
    27421 aaatgctaca aaaaataatt gaatcaaata gagtagattt agaaaagaag aatataataa
    27481 gaagtatgaa aagaaagaca agaagatgtt gacggaggaa tattaatgaa taacaatgaa
    27541 gacagaattg acaaattttt agaacttcaa agcaaaggat ttaaatttgc agagatagct
    27601 caaaatctaa agattagtca aagtacttta agaacttttt taaataaaaa aggatataag
    27661 tcagaaaaag gtaaatacat attaaaagac gaattaaatt ataataaaag tttggataat
    27721 agaaacttgg aagaagagaa agctaaggag tatgaaaaaa gtaaaaagaa tactataagt
    27781 aatagaaaaa aagtaagcac caaaaaaaag atttctaatg aaaaggcttt aagtaaaagt
    27841 gttgaacaaa ttgagtttaa tgatacaggt ttaaaaaatg caaagccaaa acaaaatgtt
    27901 aagcctaaga aagatagaaa aataaatata actcaagaag atttagataa gctttgtgaa
    27961 gtatatgatt ggtatttaga agtaaaagat tacaatataa agcctaaaaa agtatctaat
    28021 aaaaaagatg tacatataga tgatgaacac atagatgaat taaaaacaac aagaatacgt
    28081 atagataaag aaatatggaa tgattttgaa agattatgta gtaattcgaa ttttgaaaaa
    28141 catcaaatac ttacacaggc attgaaagaa tttatgaaaa agtataaaaa tctactataa
    28201 aatactacta tatgaggtgc ttaatatgaa taaaatagta aaaaaatcaa tttctctaat
    28261 gattatatta acaatattta tttttatgtt gacagcatgt gaaaaagatg aacagcctga
    28321 ttcagttgat attcaaacag aagataaaaa tgagataaaa atagatgagg gaaatgcaaa
    28381 agtattgaat ataggaaaat cagaaattat aaatatagat gaaggtgata aagtagatac
    28441 atcaacaaag gtagaaaata attcaacatt taatatatcc aatgttgaat tgatatataa
    28501 tgaatatgat gagaataaaa aaattatatc ttcggatagt aaggctttgt tggatatgac
    28561 tttaatgcct gggaaagttg cttacataga atgtgggcat aaaacttttg taaagggtgt
    28621 agaagtttat gcatatgaat atgaggcaga gggtaagatt gtgtatgtta atttaaaaga
    28681 aaatactatt aatataagaa ataataatat taagctagaa aatagtagtc agtatgaggt
    28741 gctatctaca tcagaactta aaaaagtaaa tgaatcaaat gagggaatta cgtatcaagt
    28801 aaaagtaaaa aattcatcat caaaagattt aggaaatatt attcttaaga cagcagaagt
    28861 taatgaaaat ggagaatatt taacagtaaa tcgtgtgcca tcatataaga ttttaaagcc
    28921 ttcagaagag acagatatag atatattgtg ttcaacaaag gcaaaaagtg ttgaaatagt
    28981 gggatatacg tatgatgata taaaagaaaa agccaatgtg gatattgact taaaatctca
    29041 taaagttaag atagacaaat aaaggtaggg gatacttatg aaggttttaa tagttgaaga
    29101 taataagata cttttagaaa gtgtagtaga agaacttagc aagcattttg aaactgaaaa
    29161 gtgtgaagat ggagaagaag ctttatactt agtaaatcaa aatatatatg atttagttat
    29221 tttagactta atgcttccta atataaatgg atttgatatc ctaaagaaaa tgagagttaa
    29281 taatatagat acacctgtac ttatattgac agcaaaagaa acattagatg acaaagtaga
    29341 agcatttact ataggagcta atgattattt gacaaaacct ttttatatgg aagagttagt
    29401 agctagggta tacgctatat taaggactaa tggaaagata aaagaaagaa acggattaga
    29461 atttaaatct ttatatttag atacactaga aaaaagagtg tatattgaaa aagaagaaat
    29521 aaaacttcaa aacaaacagt ttaacttgct tgagtatttt gtattaaata aaggttcaat
    29581 tttattaaaa gagcagattt atgatagaat atggggaatt gattcagatg caactattga
    29641 aatagtggaa gtatatgtaa gtaatctaag aaaaaagcta agtaaatatg gatatgataa
    29701 atatattaaa actaaacgta aggtaggata tatattcgat gataaataag aatgtattta
    29761 ccagtactaa aaatcattta ataaaaatgt atattattgt agtaggtagt tttttaataa
    29821 tcttttctat atttatatac tcatatttta ggggacttac atatagtgga attgatagtg
    29881 agataaatga tgaacttgaa tatatagtct ctcaatttaa aagaacttca tttttgaacc
    29941 caataagact gaaagatcct aaagatatgg tgtatgtata tgaagatgga aggataagtt
    30001 actatactca aaatgaatat tttgatgagt tacttccaga tagaagacta gataaaaaaa
    30061 attcgttttt taaatacaca gaaaatggat atacttttag agaattaaat gtagatgtag
    30121 gtagatacca aatacagata attagaaata tagattctga gatgaattct ttaagacagc
    30181 ttacatctgt tcttataatt ggaatattaa tttctgtaat aattacttac tttgtggctg
    30241 tatatctcac tagaaaagct ttaattccaa tagaaacagc atggaaaaat caagctaagt
    30301 ttatacaaga tgcttctcat gaattaagaa caccaataac aatagtttca tcaaaattag
    30361 aaagtatgtt aaaatcccca gaaagtacag taaatgatga agttgaaaca atagctactg
    30421 caatgaagga aactagaaga cttaaaaaaa tgataactga tttattgtct cttactaaag
    30481 aggactctat tgttaaagtt aatttagaag aaatagactt agaaaaatta ttggaagaaa
    30541 tatcagaaga ctatattgac attgctgagt ttcaggaaaa aagattcgtg tttaattcta
    30601 aactgaagaa taaagttata ataacagata aaaataaatt aagacagctt atattaattt
    30661 tcattgataa tgcctttaaa tatacaaaat tgggtgatga gatagcatta gaattaaaag
    30721 aagatataga ggatgaggta actttactta taagtgacac tggtataggc ataaaaaaag
    30781 aagagatacc tcttatattt gatagatttt ttagaagtga aaatgtaaga aataaagatt
    30841 tagaaggttc tggaatagga ctttcaatag ctcgcatgat tagtttaaac ttatctattg
    30901 atataaatgt aacttctgat gtagatattg gaactacatt tgaattgtca ataccaaaaa
    30961 agttaaaata ataaaaatat aaaaaattgt ttttagaaat gaagaatggg tatactaatt
    31021 agtataaaat ataaaaagac cttataaaag taaatttata tttataaatt tcatagtata
    31081 attatatagg gataataaag tttaatagga ggatttaaaa atggcaaaag ttataaatac
    31141 atctgaattt agaagtagtg ttgaaggtag taagggagta gttgtagttg atttctttgc
    31201 aacttggtgt ggaccttgta acatgttggg acctgtattt gcagaattag gtgaagagat
    31261 gaaggataaa gctagatttg taaaagttga tatagatgag agcttagaaa tagctcaaca
    31321 attcaatgta tctacagtac caactatgat tatatttaaa gatggaaaac cagtagaaac
    31381 tttaattgga ttcatgccaa agaacaaaat tgaaatgcaa gtaaaatcat atttataaaa
    31441 aatgggtgag tattatgaga tatgatatag ctataatcgg cagtggtcca gctggattgt
    31501 ctgctgctat aaatgcaaaa ataagaaata aaacaattat catgtttggt aatgataatt
    31561 taagtaataa gcttgttaaa gctccttcaa tagataatta tttaggtttt tatgatataa
    31621 gtggtgatga attaaaagac aagtttaaat cacatataga tagtatggat atttcaattg
    31681 aaaataaaag aataaataat atttatgcta tgggagaata ctttacaata atgtctggaa
    31741 atgatatgta tgaagctact actgtaatcc ttgcaactgg ggtagagtat actagaccaa
    31801 tcaagggtga agaagaattt ctaggaagag gtgtaggcta ctgtgctaca tgtgatgcac
    31861 cactttatag aaataaaaag gtagcagtta taggatataa tgaagaatct aaagaagaag
    31921 caaatttttt aagtgaactc acttcaaaga cttattttat acctatgtac aaaaaagata
    31981 atcttatgag aagttcagat aacctagatg attctattga agttatacat gacagaccag
    32041 tacagataga tggagataaa cttgtaaaca aagtatcttt taaagaaaac cacattgaag
    32101 ttgatggagt attcgttata aaagatagta cggctccaag tgcattggtt cctggaatag
    32161 agattgatgg cattcatatt aaagttgaca ataatatgaa gactagtata gatggatgct
    32221 ttgctgctgg agattgtgtt ggaaaaccct attcttatat aaaagcagct ggtcaagggc
    32281 aaatagcagc tttaaatgct gtttactatt tagataaatt aaagagggct taatatttat
    32341 attgattaat tttttaaaga tatttataaa aaactgtctt gaaataattt tattatttca
    32401 agacagtttt ttatttttaa gttattaata aaagtatttt aaaatctata tgtaattact
    32461 tttattaata aaattcaaag ttatattagt aaaaattgga attatttata atatactcca
    32521 aaatttaaaa ataatggttg aaaaatctaa ttaagagtac tataatttaa ttaagtaatt
    32581 acttaatcaa aacgaggtac ttatggaaaa cttggttaaa atatttaaag cattgagtga
    32641 tgaaactaga cttaacatac ttatattagt atccaagaga aatatatgtc aaaaggggat
    32701 ttctaaatat ctagggattt cagattctgc tgtttcacaa catataaaaa tattaaaaga
    32761 tgttgggata ataacaggat ataaagaagg atactatgtt ttatatcata ttaataaaga
    32821 atcatttaat atatgtgtag attttataaa ttctatgtta agtaattcta gtgaaagctt
    32881 tatagatgta tttgatgtaa atacaataca tctaggatgc agtaaagaat gtaaatctat
    32941 aaaaaaatgt tgtaagagaa gggagaaata ataatgaaag tatgtatacc agtagaggag
    33001 aataaaggat tggatagtaa accatatgga cattttggtt ctgctccaat ttttgttgtg
    33061 tgtgatttag aaagtggaga agttaaatct ttagataatg gagatttaga tcatgaacat
    33121 ggaaaatgtc aaccattaaa agcattgtca gggacagctg tagatgcagt agttgttgga
    33181 ggaataggac aaggagctat aattaaatta aatggaatgg gaataaaagt ttacagagca
    33241 gaaggtgata ctataagtgc taatttagac ttacttaaaa atggaaaatt agtagagttt
    33301 ccatcagacc atacttgctc acatgacgga tgtggacatc attaaaaaaa acagctgatg
    33361 aaatatatac ttcatcagct attttttctt ttaataaata cgattttatt cttttaaaac
    33421 caaaatttag atttttatgt tttttgtagt atccttaata atatttcaag tttacaagtt
    33481 tactactttt agattttttt tgtatgtttt tctatatagt caatatcatt taatatgtca
    33541 ttgagttctt tattaagtgt ttttaaatca tcaccatcta cattgtagtt taaaaatagt
    33601 tcctctacat tatcaatgat agaattgact tttctagtaa cttcaacaaa tgtcttaaag
    33661 ttactactat ttttagcatt tagaaatttt tttaaatcct ttgatataaa tgatactatt
    33721 tcatattcat cattaaatag acctctacca ataggatatg gttcaattct ctgtaaaaaa
    33781 tattggtctt tagcattaat attataagta taagatattt cccaaccgtc tcctaaatca
    33841 aacttgataa aatataatgt actacttact tttgatattc ttgtggcacc aagctgtctt
    33901 aaaagaactt caatcgaatc accttgaaca gtattaatat tcatatatac acatcccctt
    33961 tagtattatt atactatatt ttttaaaatt ttataattaa ataaacagta gatataataa
    34021 tagatataat cataagtgga aaacctattt tgaaatactc cttaaaagag ataggatgac
    34081 cgtgtttatt acctatacct gctagtacaa cattagcaga tgctcctatt agtgtcccat
    34141 ttcctccaag acaagctcca agagatgttg cccaccatag tggcattaca tcaatacctt
    34201 cagcttgcat agtcaaaata agaggaatta gtgttgcaac aaatggaata ttatctaaga
    34261 aagaagagac tatagctgat aaccataata tcaacaacat tgtaaataca agatgtcctt
    34321 ctgtaagtcc aatcaatgct tgagccaatt tgtttattat cccaacttct actagtccac
    34381 caactactac aaataatccc ataaagaata aaattgtgga ccattcaata cctgccataa
    34441 tttcatctac atcttgtttt cctattaaaa gcattataga tgctcctgtc agtgctacaa
    34501 cagaagaatc tatgtggatt gtactgtgaa acataaaacc aaaaagtatg aatgctatta
    34561 atataaggct ttttagaagt agaggtttat ctttaacaga ttttttttca tctagtttta
    34621 atattgcatt tttagctctt tcattcacaa caagttcttt tccataaata aatctaaagc
    34681 atattatagt tatagcaagt attactataa cagcaggacc taaatttatt acaaaatcca
    34741 taaaactaag attggcagca ctaccaatca taatatttgg agggtctcct ataagagtag
    34801 ctgttcctcc tatatttgaa gctaaaatct gtgttattaa aaatggaact ggattaagtc
    34861 ctaatatttg tgtaataact atagtcattg gtccaataag taagacggtt gtaacattat
    34921 ctaatacagc tgataaaata gctgttataa tagcaaaaca aatcattatc ttccatgggt
    34981 cacctttagc tttctttgca gtccagatag ctatatattc aaataaccct gagtttttga
    35041 caacagctac aaatagcatc ataccaacta atacaccaat agtattgaaa tctatatggc
    35101 ttaatccttc atcaagtgta agtatattga atattatcat taatagtgca ccaccaacag
    35161 ctgctacgga tctgtttacc ttttctgtaa taatagctgc cataactatt aaaaatatac
    35221 atatagctat tatttgttga aattccataa tataagtacc tccatttgta ttattttgtg
    35281 cctaatgcta gtactatata tagtattact tttttattgt tttttcaatg gatgtatgaa
    35341 agtatattat ttaacaaagt ttttgagaaa ttgacagaat ttaaagaaaa tttttgttat
    35401 ttaaataaat tttaaaatta ttccattgat aataatatta aacgacaaac gaaaaaatat
    35461 accctttaaa ctagaattta ttgtatccaa
//
LOCUS       DACTZW010000039        33661 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.039, whole genome shotgun sequence.
ACCESSION   DACTZW010000039 DACTZW010000000
VERSION     DACTZW010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 33661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33661
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.039"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            417..3071
                     /gene="adhE"
                     /locus_tag="JAM15_10115"
                     /gene_synonym="adhC"
     CDS             417..3071
                     /gene="adhE"
                     /locus_tag="JAM15_10115"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HAT6798607.1"
                     /translation="MAHKEQVIIENKKENEVMSVGLDTVNNVESLVKKLAKIREAQKI
                     FATYTQEQVDKIFLAASLAANKQRVPLAIMAQKETGMGIAEDKVIKNHYASEYIYNAY
                     KETKTCGVIEKDEAFGMTKIAEPIGVIAAVVPTTNPTSTAIFKALLALKTRNGIIFSP
                     HPRAKNSTIEAAKVVLEAAVLAGAPEGIIGWIDEPSLELTTTVMKEVDLTLATGGPGM
                     VKSAYSSGKPAIGVGAGNTPAIIDESADIKTAVNSILVSKTFDNGMICASEQSVIVLE
                     NIYNEVKKEFKERGAYLLDKDETEKIRNIILVNGGLNSKIVGQTACTIAKLAGFEVPV
                     DTKVLIGEVESVEIEEAFAHEKLSPVLAMYKASDFDDAVRKAEKLVEDGGFGHTSSLY
                     IDDVNQREKLDKFTSAMKTCRILINTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVS
                     ENVGVKHLLNIKTVAERRENMLWFRAPGKVYFKKGCLGVALKELKDVMNKKRAFIVTD
                     TFLYNNGYTKAVTDLLDEMNIKHTTFFEVEPDPTLECAKIGAKAMREFNPDVIISIGG
                     GSAMDAGKIMWTLYEHPDVDFQDLAMRFMDIRKRVYTFPKMGEKANFVAIPTSAGTGS
                     EVTPFAVITDQDTGVKYPLADYELMPNMAIVDSDMMMNMPKSLTSASGIDALTHALEA
                     YVSMLATDYTNGLALQAIKSIFEYLPRAYDNGAKDPEAREKMANASTMAGMAFANAFL
                     GVCHSMAHKLGAFHHVPHGVANALLITEVMKFNSSDAPKKMGAFSQYKYPEALKRYAE
                     IASFLGLKGNSDEEKFQSLLVAIEDLKLKVGIPKSIKEFGVEEPKFMDSIDEMVIQAF
                     DDQCTGANPRYPLMNEIKDMYLNSYYGR"
     gene            3347..5567
                     /locus_tag="JAM15_10120"
                     /pseudo
     CDS             3347..5567
                     /locus_tag="JAM15_10120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439757.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
     gene            5821..6483
                     /locus_tag="JAM15_10125"
     CDS             5821..6483
                     /locus_tag="JAM15_10125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798608.1"
                     /translation="MIDVSIDDKLKERWPNAKLGCIQAKVAVNKSSEKLINEINEFCD
                     TINQSLKVEDITKLDKIKDARNAYKELGKNPSRYRTSSEALVRRIIQGKGLYTINNIV
                     EINNLISIKSLYPVGTYNVSKLHSPVCFTVGDEGEQYKGIGKELINIENLPILSDSVG
                     KFGSPTSDSERAMITEDANEILICIFSFSQESDIEEYFGYAKELLKEYADGKDIETKI
                     IK"
     gene            6853..8262
                     /locus_tag="JAM15_10130"
     CDS             6853..8262
                     /locus_tag="JAM15_10130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HAT6798609.1"
                     /translation="MIDGKEVKQESGQKNLKFKIAIVVGVLFVAYIGMAIFFRNHFYF
                     GTTINGVKASGKTVEQVNDLLTSSTNSYTLNLEERNNKKEQIKAKDIDLKFTPDDKVQ
                     KIKDSQSAIGWIGGIFKSKEYNNMITLSYNKDLLEKRFNALSCFDSKNVVEPKSAYPK
                     YDSTKNAYVIVPEVLGNKVKKDDFYKLVQNSINSGNTSISLDESKVYEAPNNTKDSEK
                     LKQAIKTLDKYVGVVVTYDFSDRKETLDGSEINKWLKVDSEKNYDITFDNDAMVEYTR
                     SLSKKYSTFGDSRPFKTATGKDITISGGIYGWLIDKKKEAEALVDVVKAGKNVTREPI
                     YIQKAVSRNKDDIGNTYVEISLSGQHMWFFKNGEMLVSTDVVTGDLARGFATPSGIYP
                     LNYKARNVSLTGQGYSSPVSYWLPFNGNIGIHDATWRNSFGGGIYKSSGSHGCVNTPF
                     SKAKKIYENIEPGTPIILY"
     gene            8377..8652
                     /locus_tag="JAM15_10135"
     CDS             8377..8652
                     /locus_tag="JAM15_10135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798610.1"
                     /translation="MNEKLTKILEEAKNDDEFRKELIKTREQRDVMDSFCKVVTSRGY
                     DITVGELFSMGEEYTSNLLKSVNGGAAYPIEDWSDWYEDFFIMLSNI"
     gene            9282..9593
                     /locus_tag="JAM15_10140"
     CDS             9282..9593
                     /locus_tag="JAM15_10140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798611.1"
                     /translation="MAFEIIKSIVEAEQTADSIKVKAVTDAESIRADAVNKCESIFAD
                     VKKQAKLMEETLIEKAVTDSRAEVDKILANAKSECLKIEKTAEERKSKAIEAVIGKVV
                     R"
     gene            9595..11520
                     /locus_tag="JAM15_10145"
     CDS             9595..11520
                     /locus_tag="JAM15_10145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HAT6798612.1"
                     /translation="MAIVNMNKISIVGLEAQKSQILKLLMNRGFVQIDDSAFLTEEEE
                     LKNYLVKDSEESEVIMLEQKMSHVNQAINIVSSLVKQKKSLLAPKREFNKIDSEKEGQ
                     VYAEALELNNLHKEIGTIRSNINLLNNNKSMLEPWVNFDIPLENMETKYTKTILGTVP
                     ISANIDALRVKLEDEIPESVIGIVNSDKLMNYVYLITLKETFDDVLEVLKEFNFSVVS
                     LPNEEGTPLQAIKKYNEMIIRQENVSKDKTEEIKRHADSIHMLENLYDFYTIERDQKK
                     IIERLVKTKTTFCLNGWLPSKRADELIKEITEKFDCCVQTEEGSKEEGFPILLENNKL
                     VTPFESVTNMYSYPSTKDIDPNTILTFFFVVFFGMMLSDAAYGLIIAVVCGFVVYKLK
                     IQKGEGNLIKLIGICGVSTTVWGLIFGGILGDLIPIKALINPLEDVMTLMGMSLLFGI
                     IHIYVGLGIKAYTLIRSGKVIDAIFDIGFWYLCITGVCLLIIPFVAGDIGVFSEVGKY
                     LAIIGAIGLVLTQGRSFKGIPVKLFKGFSSLYGITSYFADILSYTRIMALCLTTGVIA
                     QVINLLGAIAGPILAVVIGVVGHTINLLINALGAYVHTSRLQYVEFFNKFYEGGGVPF
                     VPFKYKTKYTSINKKEM"
     gene            11523..12014
                     /locus_tag="JAM15_10150"
     CDS             11523..12014
                     /locus_tag="JAM15_10150"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HAT6798613.1"
                     /translation="MEFLNALGNGQFLAISGAAIAALFAGMGSAKGTSIAGQAAAGVV
                     TEDPSKFGQLLVLQLLPGTQGLYGFIIAFLILSKAGIIGGDAIPTSAQGLQLLMAGLP
                     IGLVGLVSGIAQGKAAAAGVGIVAKRPEELGKAITFAAIVETYALLGLLVSFLAYNGI
                     AIG"
     gene            12066..12629
                     /locus_tag="JAM15_10155"
     CDS             12066..12629
                     /locus_tag="JAM15_10155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798614.1"
                     /translation="MGNEQKMIDRIIADAKQEAQEILDKAKSEADLKVNSANEKAEKE
                     MASYTKLAEAEAEKAASKEISGAYMEAKKQILSKKQEILEEVILEAKNKLLNLKDNEY
                     EEIILNMIEKSNCTDDSEIVLSKKDKKTLKDVLSKKGIKVSDETRDITGGFIVKKGDI
                     EYNYSFEAIIAVEHEYIEQIAAEILFN"
     gene            12644..13621
                     /locus_tag="JAM15_10160"
     CDS             12644..13621
                     /locus_tag="JAM15_10160"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit C"
                     /protein_id="HAT6798615.1"
                     /translation="MAEEKTYPYAVARIRVLEKQLLNRQMFIQMAEAKSPEDSLRIIA
                     EAGYADTSNNNIHNFENILTQELSKTYEILKSLAPEEKFVDVFLYKNDYHNLKVLIKE
                     EISGVDGEKYLIDGGTIPLIKLRESLANRSFSDLPKIMSSAILEAFDVYNKTQNGQMV
                     DIVLDKATFTSMKETAKESQNKFVIDYVMKVCDLTNLKSFIRVKNMKKDFDMFMNVFV
                     SGGSLDKEKFLEAFSSDTPASCFKSTSYSDVCKNGMDSGFTVFEKLCDDYLMEYVRGA
                     KFKPLTLEPLIAYLYAKESEIKTIRIILTSKLNNIDADTIKERLRDAYV"
     gene            13608..13931
                     /locus_tag="JAM15_10165"
     CDS             13608..13931
                     /locus_tag="JAM15_10165"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HAT6798616.1"
                     /translation="MLMYKVGVVGDKDSIMGFLALGIDIFPAYDSDEIKKSIHKLVED
                     EYAIIYITEQASLLAKESIAKYKDYQLPAIIVIPGIGGSMGLGMNEVRESSKRAIGAD
                     ILFKE"
     gene            14048..15826
                     /locus_tag="JAM15_10170"
     CDS             14048..15826
                     /locus_tag="JAM15_10170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase alpha chain"
                     /protein_id="HAT6798617.1"
                     /translation="MKTGTIVKVSGPLVVAEGMRDANMFDVVRVSDKHLIGEIIEMHG
                     DKASIQVYEETSGLGPGEEVVSLGMPMSVELGPGLISTIYDGIQRPLEKMYDISGTNI
                     TKGVEVSSLDRTTKWEFKPKKSVGDKVVAGDIIGGVQETAVVECKIMVPYGVKGTIKE
                     IYSGEFTVEDTVCVITDEKGNDIPVTMMQKWPVRKERPYREKKTPDSLLVTGQRVIDT
                     FFPITKGGVAAIPGPFGSGKTVTQHQLAKWADADIVVYIGCGERGNEMTDVLLEFPEL
                     KDPRTGESLMQRTVLIANTSDMPVAAREASIYTGITIAEYFRDMGYSVALMADSTSRW
                     AEALREMSGRLEEMPGEEGYPAYLGSRLAQFYERAGKVNCLGMDEREGTLTAIGAVSP
                     PGGDTSEPVSQATLRIVKVFWGLDASLAYKRHFPAINWLTSYSLYQEKVDVWADKNVN
                     DNFSAQRAQAMKLLQVESELQEIVQLVGVDSLSDGDRLILEVTRSIREDFLHQNSFHE
                     VDTYTSLHKQYRMMGLILKFYKSAQDAIKQNVTINDIIKLSVLEKIGRAKYVEEGDID
                     AAYDSIEDEIDNELADLIKKRGAEEL"
     gene            15823..17196
                     /locus_tag="JAM15_10175"
     CDS             15823..17196
                     /locus_tag="JAM15_10175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006428724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HAT6798618.1"
                     /translation="MIKEYKSIQEVAGPLMLINGVEGVKFDELGEIELSNGEIRRCKV
                     LEVNGDTALVQLFESSTGINLAESKVRFLGKSLDFGVSPDILGRVFSGMGRPIDGGPE
                     IIPDKRLDINGAPINPAARDYPAEFIQTGVSAIDGLNTLVRGQKLPIFSGSGLPHANL
                     AVQIARQAKVRGTDSKFAVVFAAVGITFEDAEFFISDFKATGAIDRSVVFVNLANDPA
                     VERVSTPRMALTAAEYLAFEQDMHVLVIITDITNYAEALREVSAAKKEVPGRRGYPGY
                     LYTDLATMYERAGKMKGHEGSITMIPILTMPEDDKTHPIPDLTGYITEGQIILSRELY
                     KKDIQPPIDVLPSLSRLKDKGIGKGKTREDHADTMNQLFAAYSRGKDAKELMAILGES
                     ALSEIDLMYAKFADEFEKEYVSQGFRTDRTIEQTLEIGWKLLSMLPKSELKRIRDEYF
                     EKYMPKE"
     gene            17202..17870
                     /locus_tag="JAM15_10180"
     CDS             17202..17870
                     /locus_tag="JAM15_10180"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HAT6798619.1"
                     /translation="MARLNINPTRMEMTRLKKLLKTATRGHKLLKDKLDELMKQFLEI
                     VRENKRLREEAENALDTAYKNFIIARAVMSQEYLGSALMMPKQSVSVDVSTRNIMSVD
                     VPVFDFKTENNQSDIYPYGLAFTSGELDSAMEAFSDAMQPLLRLAESEKSAQLLAQEI
                     EKTRRRVNALENVMIPNYIETIKYIAMKLEENERASTTRLMKVKDMVLKKALEEKKKN
                     DLVV"
     gene            18148..19197
                     /locus_tag="JAM15_10185"
     CDS             18148..19197
                     /locus_tag="JAM15_10185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HAT6798620.1"
                     /translation="MKEFIFTCLCIVVITFMTSCISTTPQTTQGKGNNKLTIYAALEE
                     EQIAYYMEGFREEYPNIDVEIVMDSHGVIASKLLAEKDNPQADIIWGLSAMNMIELKK
                     DGALEAYKPKNYDKVDKKFKDTEDDVSWVGMSVPETAIVVNYKELKKLGIDIPKSYED
                     LIKPEYKGLITMPNPASSGTGYLTVSGLIQMMGEKDAYNYMDKLHKNIATYTHSGSKP
                     AKLAGSGEYPIGITLGYRATQQLSSGEPIEVVFPKEGSGWDLEANALVKKDNIKKEAK
                     LFLDWAISDSAMDRYAHEVAVTSIKTDNPVPKGYSKQPFEQLIKEVDLNSAAKNRSTV
                     LKTWESKYGSKSESK"
     gene            19293..20282
                     /locus_tag="JAM15_10190"
     CDS             19293..20282
                     /locus_tag="JAM15_10190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAT6798621.1"
                     /translation="MSYLKINNVFKSYDQKRVLNNISLDIEEGEFLCLLGPSGCGKTT
                     LLRIIAGLEDVNSGTIILQDKDITNLEPSKRGFGIVFQSYALFPNMTAYNNIAFPLKE
                     RKVSKEKIDNKVKEVLETVGLTNEAHKYPKALSGGQQQRIAIARALALEPKFLLLDEP
                     MSALDAKVRHKLRMDIKRLQKELNITTIMVTHDQEEAITMADKIAILNGGDIMQIGTP
                     EEIYQNPQNLFTAQFIGDTNCFDNGDSILTVRPEYVQIEKSTKENYQGIISNIEFRGN
                     LLRVEIKDKLNENFIISDVSIKEWVNLNLVEGDLVKISIDEKYYLKYPKVKGA"
     gene            20287..22005
                     /locus_tag="JAM15_10195"
     CDS             20287..22005
                     /locus_tag="JAM15_10195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HAT6798622.1"
                     /translation="MNNNAISSKSISLKSKMNLDIKKCMLTVLVMSLVIFLLAPIIYL
                     FVQAFLDKDGVFVGLQNFQEYLASESLLNSLKNTVFVSVISTVISLTLALVYAYALTR
                     TKIKFKCFFKSLAMFPMFAPTMMHAIGLVYLFGNQGLVTNLLGVHVPIYGAVGIILAQ
                     IIYVFPQSFQILYISLSSTDYRLYEASNTMGISKIREFISITIPSIKYSLISSAFVSF
                     TLCFTDFGAPKVIGGEFNVLSIDVYKQIIGQQNMPMGATVSILLLIPAIISFIVTKKI
                     EKNQNSYITSKSIPYKVKTNKLRDSILGGVVGIIAFGIIAVMLTVILSSLISVWPYDL
                     RLTLEHFSMKNSIDGIKPFINSIKMSLLTAILGTSFVFLFAYLNEKTEKAPYLKSFGY
                     FLSTLPMALPGLVLGIAYVLFFNKLEFNFMDTIYIKNLFNGLYGTLLIMVICNIVHFF
                     SVAFITATTAIKKVDKELDMVAKSMGINSASILKNVTIPLCLPAVLENFMYFFLNSMV
                     TISALVFIYTASSKVAAISIVQLDDKGSTAQAAALAVLILVTNILVKVIYEFIKNRLE
                     KRTNFN"
     gene            22447..23178
                     /locus_tag="JAM15_10200"
     CDS             22447..23178
                     /locus_tag="JAM15_10200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTRA domain-containing protein"
                     /protein_id="HAT6798623.1"
                     /translation="MGRAKYYDIYIDLKNRIENKEYLYQDLLPSEYKLIEEYSCSRNT
                     IRRAIQELANQGYVQSKHGKGVFIIYRANTQSEFLLGGTESFKESAIRNNKEYKTKVV
                     HFEEIIIDDKKSQITNFEVGTEVYYIQRVRILENKPSIIDHNYFMKDIVKDINEEIAS
                     NSIYEYMENELNETIVTTKRTMTVEKATKLDKKYLELGDYNCVAVVSNNTYNAQGIMF
                     EYTQSRHIPDGFIFFQQSQRINNIK"
     gene            complement(23194..24933)
                     /locus_tag="JAM15_10205"
     CDS             complement(23194..24933)
                     /locus_tag="JAM15_10205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798624.1"
                     /translation="MNIKEIPFSYFGSYMSISYSDELGFTLKSLRGKSKQNMDVLRII
                     PTVNNIPVDYEFEADYFSILIKFNNGSISICFDGDSKILFYGKGKNVGLKLDTLPVYN
                     FEYNYLMGKKDSEYCVINSYKNLTKFLVFSVDGKVNLSQNIFIDDCASTNKANNTSII
                     DVNNNTDNEFTCIIEDIPTHMKVPDYKEYNFETSLNNTKKLFNEYYLAQPKVDEKYKN
                     SLLRASYINWSSFVKPQGYLKRYTILASNSTFLGAWSWDHCFNALALAGVDDKLAFDQ
                     MAVLFDYQDEYGQIPGSLSDSTIRWNFTKPPIQGLFFNKMMKKINFTKETLEEIYNYI
                     EKQVLFYIKFKDSNMDGIFEYHHGNDSGQDNSTIFKGVMVVDTPDLTAFIINAMDMLA
                     KVAEKLNKYSEKEYWANKADELTKLFLSYFIVDDLPVARETLTGKILPNNALLPLVSL
                     VLGNRLPKYTRDKMIDLIISERYLTKCGIATEAIDSDEYQDDAYWRGPIWAPTTLLFV
                     EALEECGENELAIDIAKRYCELVDKNGFAENFNAITGEGLRDKSFTWTASTFIYLAAK
                     VYEYNTQRINNIK"
     gene            25182..26615
                     /gene="treB"
                     /locus_tag="JAM15_10210"
     CDS             25182..26615
                     /gene="treB"
                     /locus_tag="JAM15_10210"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS trehalose transporter subunit IIBC"
                     /protein_id="HAT6798625.1"
                     /translation="MRKNKILNSKESISQIIEYVGGKENIQSATHCVTRLRLILKDTN
                     KANINKLEGIDIVKGCFNAGGQFQIVIGVGVDKVYKDLIEQTGAEEVSKEEIKQQVNE
                     KSNKLQKFIRVLADIFIPILPAIVASGLLMGVNNMIANPGIFYEQSVIEVNTGIAGIS
                     GIINLIANTSFTFLPALIGWSAAKKFGGNPLLGVVLGLVLVHPALMSAYDFAANPSAA
                     PTWDIFGMKVAQVGYQGQVIPVLIATYILTKLELFLKKTVPDAVQLVLVSPIALLITG
                     MLTFVVIGPITMTGANMITNGVVYLFEVAPVFAGALYSFISPPLVITGMHHLFLGVNL
                     QMAGTLGYVTLWPISETVTLAQGAATLAMFFILKNNKNLRGVSITSTISAWLGITEPA
                     IYGINLRFRYPFIAVMVASAIGGAFISYHNVKATAVGVGGVFSFLSVMPQYWGVYFTG
                     MAITFVITIGLTYLFYKSGKFKTNDNI"
     gene            26678..28336
                     /gene="treC"
                     /locus_tag="JAM15_10215"
     CDS             26678..28336
                     /gene="treC"
                     /locus_tag="JAM15_10215"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HAT6798626.1"
                     /translation="MLDFKKSVVYQIYLKSFNDTTNNGLGDLNGITEKLDYLEFLGVD
                     YVWITPFFVSPQNDNGYDVADYYNIDPIYGTMDDLENLIKEAKKRNMGIMLDIVFNHT
                     STEHEWFKKALKGDKYYKDFYIFKNPKEGKSAPTNWESKFGGNAWEFVEKFNQYYLHL
                     FDKTQADLNWENPNVRKELKNILKFWIDKGIKGFRFDVVNLISKPEKYEDDLQGDGRH
                     FYTDGRKVHQYLKEMCEESGVLENDMLTVGEMSSTTIENCIKYSNPNEKELSMCFNFH
                     HLKVDYKNQNKWMLQDCDFIKLKKLLNEWQIGMEKGNGWNALFWCNHDQPRIISRFGD
                     DKKYYKESAKMLATMIYLLRGTPYVYQGEEIGMTNAYFTNIKQYVDVESLNYFDILKS
                     QGMKDGEIYNILQERSRDNSRTPMQWNNSKNAGFSESKPWIEVINNYRNINVENSLKD
                     KDSIFYYYKKLIELRKKYDVVAYGDFKPLLEENDSIFAYKRCYEKESLVVLNNFYDKE
                     IDVILDNEELEKYKCIISNYGDRKVTSTITLRPYECMALFKNEK"
     gene            28584..29288
                     /locus_tag="JAM15_10220"
     CDS             28584..29288
                     /locus_tag="JAM15_10220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAT6798627.1"
                     /translation="MKEPIYKVIENHVRELINSDSLKEGDLIPSEKQLSEEFNVTRMT
                     VRSALNNLVKEGYITRQRGVGSIVIANNIYDNISSVSGFTKEMESKGYKVSNILVSLE
                     IVQADENLSSKLNISLEENVWEIKRVRLANDARVSYMITYMPVKLFPNLNKTHCENSL
                     YNFVEEVCGYKIAMSEREVQAVISNEECMDNLKLEEPEPLLYISQICKLQNSEIFEYS
                     HTYHYGYTLTLNAVVE"
     gene            29491..29799
                     /locus_tag="JAM15_10225"
     CDS             29491..29799
                     /locus_tag="JAM15_10225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017435008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAT6798628.1"
                     /translation="MKIMLACSAGMSTSLLVTKMEDAAKENGIEAKIWAISEVNLKNE
                     IENCDVLLLGPQVRYVLGKATEMAKPYNIPVEVINMMDYGRCNGKAVLDRAVELNSSK
                     "
     gene            29821..31134
                     /locus_tag="JAM15_10230"
     CDS             29821..31134
                     /locus_tag="JAM15_10230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAT6798629.1"
                     /translation="MEKFMSFMDKYIVPVAAKIGAQRHLVAVRDAFIVMIPITMVGAL
                     GTLINNLPLEAYKNLMASIFGENWTTFGGDLWWGAIGTMAVFLVIGVAYFLAKSYESD
                     GLQSGLIALSIFFIMAPQIGKIVPEGGTTVVEGWGMIQQTYLGTAALFSSILIGLLST
                     EIFVRLSKVKKLTIKMPDGVPPAVSRSFAKLIPGMLTIMIFTVIGIFIKMLSNGSFLT
                     DILNTYLGAPLSNVADSLGSTMLIAFIIHILWTVGLHGANIALPFTETILMKLGGENA
                     ALAQAGATEGYHVLAGAFFDAFVYLGGSGMVLGLIVALLIAGRRRKEMIVLGGPPAIF
                     NIGEPLIFGLPIVLNPIFMIPFVLAPVICSAVSYLAIDFGLVAPVILPKIPWVTPPIL
                     GGAMATGDWTGGALALFNLILSILIYIPFVIASEKMQANKLKINN"
     gene            31231..32541
                     /locus_tag="JAM15_10235"
     CDS             31231..32541
                     /locus_tag="JAM15_10235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAT6798630.1"
                     /translation="MKKGLKIVTIGGGSSYTPELVEGFINRYEELPVKELWLVDIEAG
                     KEKLEIVGNLAKRMVKKAGVDMKINLTLDRREALRDADFVTTQLRVGLLDARIKDETI
                     PLSHGVMGQETNGAGGLFKALRTIPVIFDIIKDVEELCPNAWMVNFTNPTGIITEAVF
                     KYTNFRRYIGLCNVPIHLKNDVAKLFNVESDRISMDFAGLNHMVYGLNVSLDGEDVTK
                     EAIDKFVKADISMQNIKAIDFNAEFVKSLGAIPCPYHRYYYKTKEMLEDELREFKEGK
                     ARGQVVKELEEQLFELYKDEKLDVKPPQLEKRGGAYYSDAACNLISSIYNDKKDIQVV
                     NTLNKGSIRDFKDEQAVEVSSVITKNGPKPISIGYLPDSVHGLVSQIKSFEVLAAKAA
                     VYGDYESALLALCINPLIPSDDLAKTILDEMLEAHKDYLPRFNR"
     gene            32567..33298
                     /gene="chbG"
                     /locus_tag="JAM15_10240"
     CDS             32567..33298
                     /gene="chbG"
                     /locus_tag="JAM15_10240"
                     /EC_number="3.5.1.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin disaccharide deacetylase"
                     /protein_id="HAT6798631.1"
                     /translation="MTKIIINADDFGYCEAVNYGIISAHNNGIVRSTSMMANMPGVEH
                     GVGLLKENKTLNCGVHMTLSCGRPLLSNLKTIVDKDGFFIRRITDEIIEKMDCDEIYR
                     ELCAQIDRVKGLGIDISHLDSHHHIHTLVSLKPVIEKIVTKYNLPIRGGFEYNLEYSK
                     VVPLIDSFYKENVSEEYFIKNIDEIMKYDVVDIMSHPAFLDDYILNSTSYAIDRTKEH
                     KILTSKKVKEFLEKNGLVISSYRDI"
     gene            33311..33628
                     /locus_tag="JAM15_10245"
     CDS             33311..33628
                     /locus_tag="JAM15_10245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAT6798632.1"
                     /translation="MDEKMIEISFGIIGFAGDAKGLAFEAIKEAKSGNIDKARECIEK
                     SKESIHKAHKFQTELIQNEANGNKTEISVILIHAQDHLMTAMNFQQLAEEFIDVYERL
                     ESK"
BASE COUNT        12992 a         3882 c         6061 g        10726 t
ORIGIN      
        1 atttttttaa ttatactata tgttgtaaat gtttgtacat ttaactatat ttactttaac
       61 ttgttaatca agttattatt ttcattttca agtattttta tttttaaact tgatagagta
      121 tcatattaaa aattcttttt ataaagtttt atttgcaaaa aatacaaaaa tataaacgtt
      181 aaaaaaataa cgttatcctt aagtttttag atgattttat tagtgatttg cgtaaaaaat
      241 aaagtgatat ctagttaaat taagtatttg taaagctaga tattattagt agaaatgatg
      301 ttatattaga taaaaaataa aatgttaaaa aaataacttg aaaatagaaa aagtaaatgc
      361 tataatgtta ataaattaac ataataaata aaaaactatc tcaggaggtt gttaaaatgg
      421 ctcataaaga acaagtaata atagaaaata aaaaagaaaa tgaagttatg tcagttggtt
      481 tagatactgt aaataacgtt gaaagcttag ttaaaaaact agcaaaaatc agagaagctc
      541 aaaaaatatt tgctacatat actcaagagc aggtagataa aattttttta gcagcatctt
      601 tggcagctaa taagcaaaga gttcctctag ctataatggc acaaaaggaa actggtatgg
      661 gaattgctga agataaggtt ataaagaatc attatgcctc agagtatata tataatgcat
      721 ataaagaaac taaaacttgt ggtgttatag agaaagacga agcatttggt atgactaaaa
      781 ttgctgagcc aataggtgtt attgcagcag ttgtacctac aactaatcca acttctactg
      841 ctatctttaa agcactttta gctttaaaaa ctagaaatgg aataattttc tctccgcatc
      901 caagagcaaa aaattctact atagaggctg caaaagttgt tcttgaggct gctgttttag
      961 ctggagctcc tgaaggtata ataggatgga tagatgagcc atctttagaa ttaactacaa
     1021 ctgttatgaa agaagtggat ttgacccttg ctacaggagg tcctggaatg gttaaatcag
     1081 catattcatc tggaaaacca gctattggag ttggtgcagg taatactcca gcaataattg
     1141 atgagagtgc agatataaaa actgctgtaa actcaattct tgtatctaag acttttgaca
     1201 atggtatgat atgtgcttct gaacaatcgg ttatagtatt agaaaatata tacaatgaag
     1261 tcaaaaaaga atttaaagag cgtggtgctt atttattaga taaagatgaa acagaaaaaa
     1321 taagaaatat aattttagta aatggaggat taaattctaa aatagttggg caaacagctt
     1381 gtactatagc aaaacttgca ggctttgaag tcccagtaga tactaaggtt ttaataggtg
     1441 aagtagaatc agttgaaata gaagaagctt ttgctcatga gaaactttca ccagtacttg
     1501 caatgtacaa ggccagtgat tttgatgatg cagttagaaa agcagaaaaa ttagtagaag
     1561 atggtggatt tgggcataca tcttcattat atattgatga tgtaaatcaa agagaaaaac
     1621 ttgataagtt tacttcagcc atgaaaactt gtagaatttt aattaatact ccttcttctc
     1681 aaggtggtat aggggactta tataatttta aactagctcc ttctcttact ttaggatgtg
     1741 ggtcttgggg tggaaattca gtatctgaaa atgtaggagt taagcattta cttaatatta
     1801 aaacagtagc tgagaggaga gaaaatatgc tttggtttag agcaccagga aaagtttatt
     1861 tcaaaaaagg ttgtttaggg gtagcattaa aagaacttaa agatgtaatg aataagaaga
     1921 gagcttttat tgtaacagat acattccttt acaataatgg atatactaaa gcagttactg
     1981 atttattaga tgaaatgaat attaagcaca ctacattctt tgaagtagaa ccagacccaa
     2041 ctttggaatg tgctaagata ggcgctaaag ctatgagaga atttaatcca gatgtaataa
     2101 tatctatagg tggaggaagt gcaatggatg caggaaagat aatgtggaca ttgtatgagc
     2161 atccagatgt agatttccaa gacctagcta tgagatttat ggatataaga aaaagggtat
     2221 atacattccc taaaatgggt gaaaaagcta attttgtagc tataccaaca tcagcaggta
     2281 ctggttcaga agtaacgcca tttgctgtta taactgacca agatacaggg gtaaaatatc
     2341 cattagcaga ttatgaactg atgccaaata tggctatagt tgattctgat atgatgatga
     2401 atatgccaaa aagcttaaca tctgcttctg gtatagatgc attaactcat gcattagaag
     2461 catatgtatc tatgcttgca actgattata caaatggatt agctttacaa gccattaaga
     2521 gtatatttga atatcttcca cgtgcatatg ataatggtgc aaaagaccca gaagctagag
     2581 aaaaaatggc aaatgcttct acaatggcag gtatggcttt tgcaaatgca tttttgggtg
     2641 tttgtcactc tatggctcat aaattaggtg ctttccacca tgtaccacat ggtgttgcaa
     2701 atgctctttt gataacagaa gttatgaaat ttaattcttc agatgcacca aagaaaatgg
     2761 gagcattctc tcaatataaa tatccagaag cattaaaaag atatgctgaa atagcttcat
     2821 ttttaggatt aaagggaaat tctgatgaag agaaattcca aagtttattg gtagctattg
     2881 aagatttaaa acttaaagtt ggtattccta aatctataaa agagtttgga gttgaagaac
     2941 ctaagtttat ggattcaata gatgaaatgg tgattcaagc atttgatgac caatgtacag
     3001 gagcaaatcc aagatatcca cttatgaatg aaataaaaga tatgtattta aattcatatt
     3061 atggaagata aatttactat aaaatagata aaataaaaac tcttatacat aaaacaaagt
     3121 tttattgtat aagagttttt ttgtttagaa aaattgatag tttttattct ttaatttaaa
     3181 attcaactaa atagtgttat tatgataata aaagaatgtt tttatggtta ttaggttgat
     3241 tttatgtgta acatttaaga atagttatat acaatataaa tgatgaatcg gtataaaaag
     3301 gatatattat ctatatgaag tattgactaa ttaggggagg agtcgaatga cagggagaaa
     3361 taaaagtttt acattaatta caattctttt tttaacatca ttatttttga caatggggta
     3421 tatctatata gaagatacaa aacatcttct tatgtcagag gcaaaaatac atataaaaga
     3481 agttgcagta caaggctctc aactagcaca aagacaaatt gaaaaagatt tagatgtttt
     3541 aaatattttt tctaactatt atgcttcaaa tccagatata cctaatgagg aaaaaatgaa
     3601 aaatctttta gatgaaatgg aaaatcaaaa attttacact atggcaatag ttgatataaa
     3661 tggtaatgct gaaaatacca aaggtgataa gttttcagtg aaagatagag aatttttcaa
     3721 aaactcaatt ataaggtaag aagtatgttt caagtccata tgttgatgaa gtaaataagt
     3781 ctataaagaa gattgctatt tcagtaccat tattaaataa tgataaagta gttggagttt
     3841 tatattgtac ttacaatatc aatactctga tgaaacttat taatgtatct ttttatgaaa
     3901 ataatagtat atcttatgtt gtaagaaatg atggtacaat tatccttcat ccgcaagagg
     3961 atagcctatc aaaaaatatt tataaattgt taaaacagga taatgatatt cgagaaataa
     4021 atagattaaa aaaagaattg caagaaaata aaacaggtgc aactgtatta aatatgttgg
     4081 aagaaagaag atatttagga tatgctacta tggataatgg gaatagtgaa aataattata
     4141 taaaagattg gaatttgatt ttttcaattc cagaaactgt tgtatttagt aattcagaac
     4201 aaataatcaa tagagctata tatgcagtgt tatttattat attaatattt attgcaatta
     4261 ttttttatat aatttatata aaaaaatcca atgaaaaaga aatattaagt ttggcttatg
     4321 aagataaagt tacccatata ggaaatcaaa ataaatttta tagagagtgt agtaagtatc
     4381 ttttagataa accatcttta aattatatta tagtatattt tgatattaat aactttaaga
     4441 tgattaatga tacttttgga tatgaatttg gtgacaattt attaattacg atagcaaaag
     4501 ctttaaaaga agaattaaca gaaggtgaag tatatgcacg actttcaagt gattattttg
     4561 caattttctg tgattataaa aatggaaaaa ataaacttat aagaaaaatt gatagtatac
     4621 gaaataatat tgaaagtaat ttgagtatag tatttgaaat ttctctgtgt gtgggtattt
     4681 attttgttga agaaggtgaa gtagatatcc aaaaggctgt aaataaagca aatatggcta
     4741 ggtctgttgc taaaggtaaa aatataaatt atgctattta taatgaagat gttaggaata
     4801 agcttagtga agaatcaatg attttagatg atataaaaat agcattggta aaaaatcaat
     4861 ttgaagtgta ttatcaacct aagttttcac ttgtaactgg agaaatgata gggagtgaag
     4921 cactaataag atggaatcat ccagaacatg gttttataag tcccgcagta tttattccaa
     4981 tagcagagaa aagtaagttg attttaaaaa ttgggagatt tgtatttgaa agggtttgca
     5041 atgatttatc tgaatggaaa aagcaaggta aaaagatagt tccagtttca ataaatttat
     5101 ctagagttga gttgtatcaa ccagatattg taaaatttat caataaaaca atacaaatgt
     5161 ataatctaag ttcagattta attgaaatag agataacaga aactgtggct attaatgagt
     5221 taaatatttt aaagaatgtt ttaaatgagt tgaggaagta tggattttct atttctatgg
     5281 atgactttgg tacaggatat tcttctatta gttgtttaag agatatgcca attgatatat
     5341 tgaaactaga taagtctttt cttaatggta ttgaacatga tgagagaagt cgcaatatag
     5401 caaaatcaat agtgtctcta gcaaaatcac tagatttagt tgtaattata gaaggtgttg
     5461 agagtaaaga acaagctgag ttaatgaaac aatttggatg tgatttagtt caaggatttt
     5521 attttgcacg accaatgcca gctaagaatt ttttagattt actttaaaac aaaatttaat
     5581 ttttatataa agcactatta tgaatgtttg attttaataa atcactgcta aataattagt
     5641 gtttttttat tttatcaatg tattgtttaa tataaagcaa aaaataattg tattttataa
     5701 aaattatatt aaaaataaat ttattttgct aataaacatg ttattaacaa aagaatagta
     5761 ctataatgta tagatgataa aaactttaat aaaaatttag tgtataggag ttgtttaagt
     5821 atgatagatg tgagtattga tgacaaactt aaggaaagat ggcctaatgc taagctgggt
     5881 tgcattcaag caaaagtagc agtaaataaa agctcagaaa aattaattaa tgaaataaat
     5941 gagttttgtg atactataaa tcaaagtcta aaagttgaag acattacgaa actagataaa
     6001 attaaagatg caagaaatgc ttataaagag cttggaaaaa atccaagtag atatagaaca
     6061 tcttcagaag cattggttag aagaattatt caagggaagg gtctttatac aataaataat
     6121 atagtagaaa taaacaattt aatatcaata aaatcattat atccagtagg tacatataat
     6181 gtaagcaaat tacattcacc agtatgtttt actgtaggag atgaaggaga acagtataag
     6241 ggtattggga aagaattaat aaatatagaa aatcttccta tattgtctga ttcagtgggt
     6301 aaatttggga gtccaactag tgattctgaa agagcaatga taacagaaga tgcaaatgaa
     6361 atattaattt gtatattttc ttttagtcaa gaatctgata ttgaagaata ttttggatat
     6421 gctaaggagt tacttaaaga atatgctgat ggaaaagata tagaaactaa aataattaaa
     6481 tagaatctat ataacaacgt tatgttaagc taaaattcaa tataaaaata agttaagata
     6541 aagaaactaa cataaaatta gtttcttttt taaaagagta gtttagtgtt acaaaaacag
     6601 atagataacc cacgattatt aaaagtatgg taatatatta atatagcaga gattgtattt
     6661 aagggatttt gaaaggggtg atttataata gtcattttgt ctaaaagata aaatggtttt
     6721 atggaaataa ctatatattt aaaaatataa ataatgatac agtaatttgg gtatataaaa
     6781 taaggcatac atggttttgt ttaaaaacca ataaagtaca taggtaatta caatgtaagg
     6841 aaggatttaa ttatgattga tggaaaagag gtaaaacaag aaagtggaca aaaaaatcta
     6901 aaatttaaga tagctatagt agtaggtgtt ttgtttgtag cttatatagg aatggcaatc
     6961 ttttttagaa atcattttta ctttggaacg actattaatg gcgtaaaggc ttcaggaaaa
     7021 acagttgagc aagtaaatga tttgttaaca tctagtacta attcctatac tttaaactta
     7081 gaggaaagaa acaataagaa agaacaaata aaagcaaaag atattgattt aaaatttaca
     7141 ccagatgata aagttcaaaa gataaaagat agtcaaagcg ctattggatg gattggtgga
     7201 atatttaaat ctaaagagta taataatatg ataactcttt catataataa agatttacta
     7261 gaaaaaaggt ttaatgcttt atcttgtttt gatagtaaaa atgttgtaga acctaagagt
     7321 gcttatccta agtatgatag cactaaaaac gcttatgtta tagtaccaga ggtacttgga
     7381 aacaaagtga aaaaagatga tttttataag ttagtacaaa actcaattaa ttctgggaat
     7441 acttctattt ctctggatga aagtaaagtt tatgaagcac caaacaacac aaaggattca
     7501 gaaaagttga aacaagctat taagacacta gataagtatg ttggtgtagt cgttacatat
     7561 gattttagtg accgtaagga aactttagat ggttctgaaa ttaataaatg gttaaaagta
     7621 gactcagaaa agaattatga cataactttt gataatgatg ctatggtaga atatacaaga
     7681 agtttaagta aaaaatacag tacttttggt gactcaagac catttaaaac tgccacaggt
     7741 aaagatatta caatttcagg tggaatttat ggttggttga tagataaaaa gaaagaagct
     7801 gaagcattag ttgatgttgt aaaagctggt aaaaatgtta caagagaacc tatttacata
     7861 caaaaagctg tatctcgtaa taaagatgat attggaaata catatgtaga gattagtctt
     7921 tctggccaac atatgtggtt ctttaaaaat ggagaaatgc ttgtatcaac agatgttgta
     7981 acaggtgatt tagctagagg atttgctaca ccatcaggta tatatcctct taattataag
     8041 gctagaaatg tttcattaac tggtcaaggt tatagttcac ctgtaagtta ttggcttcca
     8101 tttaatggga acataggcat tcatgatgct acttggagaa attcttttgg tggaggtata
     8161 tataagtctt caggttcaca tggatgtgta aatacacctt tttctaaggc aaagaaaata
     8221 tatgaaaata tagaaccagg tacaccaatt attttatact agtaaatgtg ttgctaacag
     8281 ttaagcgaag tcatcttagt ttatttagga tggcttcctt tttatataaa gcttattgaa
     8341 gtttacagaa agactactta aaaggagaaa tacataatga atgaaaaatt aactaaaatt
     8401 ttagaagaag ctaagaatga tgatgaattt agaaaggaac ttataaaaac aagagaacaa
     8461 cgtgatgtta tggattcatt ttgtaaggtt gttacatcta gaggttatga tataacagta
     8521 ggggaacttt tttccatggg agaagaatat acatcaaacc tactgaaaag tgtaaatgga
     8581 ggagcagcat atcctattga agattggagt gattggtacg aggatttttt tataatgttg
     8641 tcgaatatat agagtaacta atgatattat ctacttaaga ttaatacact gttttaaaat
     8701 aaaactatta gaactaagtg taagttttat caatctttaa aaatattgat ttatttctaa
     8761 ctagatataa aaaaattaga ttaaaaataa ggtgacaaaa atcgatatag cttgatgatt
     8821 tataaaagtt agataaaata gtgcgagata tttctaaaaa ttcaaaaaaa acaataaact
     8881 tcaagggtta gaggttgaaa aagaatataa aaaactttta tatgtaataa attaaattaa
     8941 aattataaaa aaaataaaat aaaaatttaa aatgtcgaca taacgttaat tttaaaacaa
     9001 aataacgcta ttgacaaact atatcgcttt aaattataat tattgaaaat aatggtattt
     9061 aaaaaccata ctcatgtcat agtctaaaag taagtcaaaa aaggatgtaa atctaggcaa
     9121 gtactattct aaaatatgtt ttattaagaa ataaacgttg aaaaatatta attattatat
     9181 aaaaatgctg tttatacttt aacaatgagg tagtaatcta attagaataa aaaaatctaa
     9241 ttggttatat acatagtaaa aaggtaagag aggtgatttg gatggctttt gaaataataa
     9301 aaagcattgt tgaggcagag cagacagcag acagtatcaa agtaaaagct gttactgatg
     9361 cagagtctat cagagctgat gctgtaaaca aatgtgaaag catatttgct gatgtaaaaa
     9421 aacaagcaaa gcttatggaa gaaactctta ttgagaaggc agtcaccgac agtagagcag
     9481 aggttgataa aatcttagct aatgctaaaa gtgaatgtct gaaaattgaa aaaactgctg
     9541 aagaaagaaa aagtaaggct attgaagcgg ttattggaaa ggtagtgaga taatatggca
     9601 atagttaata tgaacaaaat atctattgtt ggcttagaag ctcaaaaaag ccagatttta
     9661 aagctactta tgaaccgtgg gtttgttcag attgatgata gtgcctttct tactgaggag
     9721 gaggaattaa aaaattatct tgtaaaagat agtgaagaat ctgaagttat aatgctagag
     9781 cagaaaatgt ctcatgtaaa ccaagcaatt aatattgttt cttcactagt gaaacaaaaa
     9841 aaatccctac ttgcaccaaa aagagagttt aacaaaattg atagtgaaaa agaagggcaa
     9901 gtttatgctg aagctctgga gttaaacaat ttgcacaagg agataggtac aataaggtct
     9961 aacataaact tacttaacaa caataaaagt atgttagaac catgggtgaa ctttgatatt
    10021 cctcttgaaa atatggaaac taagtataca aaaactatac ttggaactgt gcccataagc
    10081 gcaaatattg atgctttaag agtaaaatta gaagatgaaa taccagaaag tgttattggg
    10141 attgtcaatt ctgacaagtt aatgaactat gtttatttaa ttactttaaa agaaactttt
    10201 gatgatgttt tagaagtttt aaaagaattt aatttttcag tggtttcatt accaaatgaa
    10261 gaaggtacac cgttacaagc tatcaagaaa tacaatgaaa tgataattag acaggaaaac
    10321 gtttctaagg acaaaacaga ggaaattaaa agacatgcag atagtataca catgcttgaa
    10381 aacctatatg atttttacac tatagaaaga gaccaaaaaa agattataga gagacttgtc
    10441 aaaacaaaaa caacattctg tcttaatggt tggttaccaa gcaaaagggc agatgaatta
    10501 attaaagaaa ttacagaaaa gtttgattgt tgtgttcaga ctgaagaagg aagtaaagaa
    10561 gaaggcttcc caattctgct tgaaaacaat aaattagtaa caccttttga aagtgtaact
    10621 aacatgtaca gctatccaag tacaaaagat attgacccaa atacaatttt aactttcttc
    10681 tttgttgtat tctttggaat gatgctaagt gacgccgcat atgggttaat aattgcagta
    10741 gtctgtggat ttgttgtata taaattaaag atacaaaaag gtgaaggaaa tttaattaaa
    10801 cttattggta tctgtggagt ttcaactact gtatggggtc ttatattcgg gggtattttg
    10861 ggggatttaa ttcctataaa agcattaatt aatcctttag aggatgttat gacacttatg
    10921 ggaatgtcgt tactgttcgg tattatccat atatatgtag gtttgggaat aaaagcatat
    10981 acattaataa gaagtggaaa ggtaatagat gcaatctttg acataggttt ttggtatttg
    11041 tgtataacag gtgtatgtct acttataata ccttttgttg caggggacat aggtgtattt
    11101 tcagaagtag gaaaatattt agcaattata ggtgctatag gtcttgtact tactcaagga
    11161 agaagcttta aaggtattcc tgttaagctt tttaaaggat tttcaagtct ctatggcata
    11221 acaagttatt ttgctgatat attatcttat acaagaatta tggcgctttg tttaacaaca
    11281 ggagttatag cacaagttat caacctttta ggagctatag ctggtccgat acttgcagtt
    11341 gtaatcggtg ttgtaggaca cacaataaac cttcttataa atgcactagg tgcatatgtt
    11401 catacaagta ggttacagta tgtagaattt ttcaataagt tttatgaagg cggaggagtt
    11461 ccttttgttc cgtttaagta taaaacaaaa tatacaagca ttaataaaaa ggagatgtaa
    11521 atatggaatt tttaaacgcg ttaggaaatg gtcaattttt ggcaatatca ggagctgcta
    11581 tagcagcatt atttgcaggt atgggttctg ctaaaggtac ttcaatagca ggtcaagccg
    11641 cagcaggtgt tgtaacagaa gaccctagta aattcggtca acttctagtt ttacaacttc
    11701 ttcctggtac acaaggtctg tatggattta tcatagcttt ccttatttta tcaaaagcag
    11761 ggattattgg tggagatgca ataccaacat cagctcaagg tttacaactt cttatggcag
    11821 gacttccaat tggtttagtt ggtttagtat caggtatagc acaaggtaaa gcagcagcag
    11881 caggagttgg aatagttgca aaaagacctg aagaacttgg taaagctata acatttgcag
    11941 caatagttga aacatatgct cttttaggac tacttgtttc tttcttagct tacaatggaa
    12001 ttgcaattgg ttaattataa attataattc ataagtaaaa aaaatgaaaa ggaggaagca
    12061 ctcctatggg taatgaacaa aaaatgattg acagaattat agctgatgcc aaacaagaag
    12121 cacaagaaat attggataaa gctaaaagtg aagcagattt aaaagtaaat tcagctaatg
    12181 aaaaagctga aaaggaaatg gcttcctata caaagcttgc agaggcagaa gcagaaaaag
    12241 cggcttctaa ggaaatatca ggagcttata tggaggctaa aaagcaaata ttatcaaaaa
    12301 aacaagagat tttagaagag gtaattttag aagctaaaaa caaactttta aatcttaaag
    12361 ataatgaata tgaagagatt atactaaaca tgattgaaaa atcaaattgt acagatgatt
    12421 cagagatagt attatctaaa aaagataaaa aaacattaaa agatgtgcta tcaaaaaaag
    12481 gcattaaagt gtctgatgaa actagagata ttactggagg tttcatagtt aaaaaaggtg
    12541 acattgagta caattattca tttgaagcca taattgcagt agagcatgaa tatattgaac
    12601 aaattgcagc agaaattttg tttaattaag gaggggttaa aaaatggcag aagaaaaaac
    12661 ttatccctat gccgttgcac gaataagagt gcttgaaaaa cagcttctta acagacaaat
    12721 gtttattcaa atggcagaag ccaaaagccc tgaagactct ttaagaatta tagctgaggc
    12781 aggttatgct gatacatcaa ataataatat acataatttt gagaatattt tgactcaaga
    12841 attatcaaag acatatgaaa ttcttaaaag tctagctcct gaagaaaaat ttgttgatgt
    12901 atttctttat aaaaatgact atcacaattt aaaagtgctg attaaagaag aaatttctgg
    12961 tgtagatggt gagaaatatt taattgatgg aggtacaatt cctcttatta agcttagaga
    13021 atctttagca aatcgtagtt ttagtgattt acctaagata atgtcatcag ctatattaga
    13081 ggcatttgat gtttataata agacacaaaa tggccagatg gttgatattg ttctagataa
    13141 agcaaccttt accagtatga aagaaactgc taaagaaagc caaaacaaat ttgtaataga
    13201 ttatgttatg aaagtttgtg atttaacaaa tctaaagagt tttataagag tcaaaaatat
    13261 gaagaaagat tttgatatgt ttatgaatgt gtttgtttca ggtggctcac ttgataagga
    13321 aaaattctta gaagcttttt cctcagatac tccagcatca tgttttaaat ctacttctta
    13381 ctctgatgtc tgtaaaaatg gcatggatag tggttttact gtctttgaaa aactttgtga
    13441 tgactatctt atggaatatg ttagaggagc aaaatttaag cctcttacat tagaaccact
    13501 aattgcatat ttatatgcta aagaatcaga gataaaaaca attagaatta ttttgactag
    13561 taagcttaat aatatagacg cagatactat aaaagaaagg ctaagggatg cttatgtata
    13621 aggtaggagt agttggagat aaagatagca tcatgggatt tttagctctt ggaatagata
    13681 tcttcccagc ctatgatagt gacgaaatta aaaaaagtat acataagttg gttgaagatg
    13741 aatatgcgat aatttatatt acagaacagg catcattgct tgcaaaagaa tcaatagcaa
    13801 aatacaaaga ttaccaactt cctgccatta tagttattcc aggtattgga ggaagtatgg
    13861 gattaggtat gaatgaagta agagaatcta gtaaacgtgc tataggtgca gatatattat
    13921 ttaaagaata gatgaaagtt gaataaaaga caatctcaaa ttttattggt gctaaatata
    13981 tgtactaata aaatatagga gggaatattt aaattttgat aaagtatatg attgcaggtg
    14041 agagaatatg aaaacaggca caattgtaaa ggtgtcagga ccgcttgttg tagcggaggg
    14101 catgagagat gcgaatatgt ttgacgtcgt aagagtttca gataaacatc ttataggcga
    14161 gattatagaa atgcatggag ataaagcttc tatacaggtt tatgaggaaa cttccggtct
    14221 aggaccaggg gaagaagtag tttctcttgg aatgcctatg agtgttgaac ttggaccagg
    14281 tcttatttca actatttatg atggtattca acgtccactt gaaaaaatgt atgatatttc
    14341 aggtactaat ataactaaag gtgttgaagt atcttcactt gatagaacaa ctaagtggga
    14401 atttaaacct aaaaaatctg ttggtgataa ggttgtagca ggagatataa ttggtggcgt
    14461 tcaagaaaca gcagtagtag aatgtaaaat tatggttcct tatggagtta agggtactat
    14521 aaaagaaata tattctggtg aatttactgt tgaagataca gtttgtgtta ttacagatga
    14581 aaaaggtaat gatatacctg taactatgat gcaaaaatgg ccagttagaa aagaaagacc
    14641 atatagagaa aagaaaacac cagattcact tcttgttaca ggtcaaagag ttatagatac
    14701 atttttccca atcacaaaag gtggggtagc agctataccg ggaccttttg gaagtggaaa
    14761 aactgttaca cagcatcagc ttgctaaatg ggcagatgca gatatagttg tatatatagg
    14821 ctgtggcgag cgtggaaatg aaatgacaga tgttcttctt gaatttcctg aattaaaaga
    14881 cccaagaaca ggcgagtcac ttatgcaaag aactgtgctt atagcaaata catcagatat
    14941 gccagttgct gcacgtgaag cttctatata cactggtatt acaatagctg aatattttag
    15001 agatatggga tatagtgttg cacttatggc agactctaca tcaagatggg ctgaggctct
    15061 tagagagatg agtggtcgtt tagaggagat gcctggtgaa gaaggttatc ctgcatactt
    15121 aggttcacgt cttgctcaat tctatgagag agcaggaaag gtaaattgtc taggtatgga
    15181 tgaaagagaa ggaacactta cagcaattgg tgcagtttct cctcctggtg gtgatacatc
    15241 agaacctgtc agccaagcaa cgcttcgtat agtaaaagta ttctggggtc ttgatgcatc
    15301 tttagcatat aaacgtcatt tcccagcaat taactggttg actagttatt cactctatca
    15361 ggaaaaagtt gatgtatggg cagataaaaa tgtaaatgat aatttctcag ctcaaagagc
    15421 tcaagctatg aaacttttac aagttgaatc tgaacttcaa gaaatagttc aattggttgg
    15481 tgttgattca ctttcagatg gagatagatt gatactagag gttactcgtt ctataagaga
    15541 agacttcctt catcaaaact ctttccatga agttgatact tatacatcac ttcataaaca
    15601 atatagaatg atgggactta tattaaaatt ctataagtca gcacaagatg ctatcaagca
    15661 aaatgttact ataaacgata ttatcaagct ttcagttctt gaaaagattg gtcgtgctaa
    15721 gtatgtagaa gaaggcgata tagatgcagc ttacgattca attgaagatg aaatagacaa
    15781 cgagcttgca gaccttatta aaaagagggg ggctgaagaa ctatgataaa ggaatataag
    15841 tcaatacaag aggtagccgg tcctcttatg ttaataaacg gcgtagaagg tgtaaaattt
    15901 gatgaacttg gagaaattga actttcaaat ggagaaattc gccgttgcaa agttctagag
    15961 gtaaatggag atactgcact tgttcagctt ttcgaaagct caacaggtat aaaccttgct
    16021 gaaagtaaag ttcgtttttt aggaaagagt cttgactttg gagtttcacc agatatatta
    16081 ggtcgtgttt ttagtggaat gggtagacct attgatggag gtccagaaat tataccagat
    16141 aaaagacttg atataaatgg agctccaata aatccagcag cacgtgatta tccagccgag
    16201 tttatacaaa ctggagtctc tgctatagat ggacttaata cattggttag agggcaaaaa
    16261 cttcctatct tctcagggtc tggtttgcca catgccaatc ttgcagttca gattgcaaga
    16321 caggcaaaag tacgtggaac tgattctaag ttcgctgttg tatttgctgc agttggtata
    16381 acttttgaag atgctgaatt ttttataagc gattttaaag caactggtgc aatcgaccgt
    16441 tctgtagtgt ttgtaaacct tgcaaatgac ccagctgtag agcgtgtatc tacacctaga
    16501 atggcactta cagcagcaga ataccttgct tttgagcaag atatgcatgt acttgttata
    16561 ataacggata ttacaaacta tgcagaggca ttgcgtgaag tttcagcagc taaaaaagaa
    16621 gttccaggac gtcgtggata tccaggatat ctttatactg accttgctac tatgtatgaa
    16681 agagcaggaa aaatgaaagg gcatgaaggg tctataacta tgattccaat acttacaatg
    16741 cctgaggatg ataagacaca tccaattcct gaccttacag gatacattac agaagggcaa
    16801 attatactta gccgtgaact ttataaaaaa gatatacagc ctcctataga tgttttacca
    16861 tcactttctc gtctaaaaga taaaggtatt ggtaaaggta agactcgtga agaccatgca
    16921 gatacaatga accagctttt tgcagcttat tcaagaggta aggatgcaaa agaacttatg
    16981 gctatacttg gtgaatctgc actttctgag attgatttaa tgtatgctaa gtttgcagat
    17041 gaatttgaga aagaatatgt ttcacaagga tttagaactg atagaactat tgagcagaca
    17101 ttagaaatcg ggtggaagct tcttagtatg ttaccaaaaa gtgaacttaa acgtatccgt
    17161 gatgaatatt ttgaaaaata tatgcctaag gagtgatatc tgtggctaga ttaaatataa
    17221 atccaacacg tatggaaatg actagactta agaaactcct taaaactgct acaagaggtc
    17281 ataagcttct taaagataaa cttgatgaac ttatgaaaca atttcttgag attgtaagag
    17341 aaaataagcg attgcgtgaa gaagcagaaa atgctctcga tactgcttat aaaaatttta
    17401 taatcgcaag agcagttatg agtcaggagt atctgggttc agcacttatg atgccaaagc
    17461 aatcagtttc agtagatgtt tctacgagaa atataatgag tgttgatgtt cctgtgtttg
    17521 actttaaaac tgaaaacaat caaagtgata tttatcctta tggtcttgct tttacatcag
    17581 gtgaattaga ttctgctatg gaagctttct cagatgctat gcaaccactt ttaagacttg
    17641 cagaaagtga aaaaagtgca cagcttcttg cacaagagat agaaaagaca cgtagacgtg
    17701 ttaatgctct tgaaaatgta atgataccaa attacattga gactattaag tatatagcta
    17761 tgaagcttga agaaaatgag agagcaagta ctactagact tatgaaggtt aaggatatgg
    17821 tgcttaaaaa agcacttgaa gaaaagaaaa aaaatgattt ggttgtataa ttaaatactt
    17881 ataaaaataa gtctaacatt ctactttata gaggttagac ttatttttta tgtttaaatt
    17941 aaaatgtaga tactataaaa attaatatat tgtttaaaaa cagactgtat ttaactaaaa
    18001 ataatatatt taacaaaaat ttctaaaaat taacgaactg ttaatttaca cttaacttta
    18061 tattaacaaa ttaggtgtat tatataaaca taagcaaaaa caataaaaaa caaataaaaa
    18121 aaggaaaaaa cacaaagggg ggaagatatg aaagaattta tatttacttg tctgtgcatt
    18181 gtagtgatta catttatgac aagttgcata tcaacaacac cacaaactac tcaaggaaaa
    18241 ggaaataata aacttacaat atatgcagca ctagaggaag agcagatagc ttattatatg
    18301 gaaggtttta gagaagagta tcccaatata gatgtagaga tagttatgga ttctcatggt
    18361 gtaatagctt caaaactatt agcagaaaaa gataatccac aagcagatat tatatgggga
    18421 ttatcagcaa tgaacatgat agagctaaaa aaagatggtg cacttgaagc atataagcct
    18481 aaaaattatg ataaagttga taaaaaattt aaagatactg aagatgatgt atcttgggta
    18541 ggaatgagtg tcccagagac agcaatagta gttaattata aggaacttaa gaaactaggt
    18601 atagatattc caaaaagtta tgaagattta ataaaaccag aatataaagg acttataaca
    18661 atgccaaatc cagcatcatc tggaacgggg tatcttacag tatcagggct tattcaaatg
    18721 atgggtgaaa aagatgctta caattacatg gataaattac ataaaaatat agctacatat
    18781 acacactcag gttcaaaacc tgcgaagtta gctggctctg gagagtatcc aataggtatt
    18841 acacttggat atagagctac acaacaatta tctagtggag aacctataga ggttgtattt
    18901 ccaaaggaag gttcaggttg ggacttagaa gcaaatgcct tagttaaaaa agataatata
    18961 aaaaaagaag caaagctatt tttagattgg gcaataagtg attcagctat ggatagatat
    19021 gcacatgaag tagcagttac ttccataaag acagataatc cagttccaaa aggttattct
    19081 aaacaaccat ttgaacagct tataaaagaa gttgatttaa actctgctgc caaaaacaga
    19141 agtacagtac ttaaaacttg ggaatcaaaa tacggttcaa aatctgaaag taagtaaggt
    19201 ttaaattaat aatttagatg aaagaatttt agaagaaaaa gtaggatata aaatttaaaa
    19261 taaaaaaata actatataag gagagataag atatgagtta cttaaaaata aataatgtgt
    19321 ttaaaagtta tgaccaaaaa agggttttaa ataatattag tttggatatt gaagaagggg
    19381 aatttctatg tttactcgga cctagtggat gtggtaaaac tacattactt agaataatag
    19441 caggtcttga agatgtaaat agtggaacta taattctcca ggataaagat attacaaatt
    19501 tagagccatc aaagagaggt tttggtatag tatttcaatc atatgcatta tttccgaata
    19561 tgactgctta taacaatata gcttttccac taaaagagag aaaagtttca aaagaaaaaa
    19621 tagataataa agttaaggaa gtacttgaaa cagttggatt gactaatgaa gctcataaat
    19681 atcctaaagc attatcaggt gggcaacaac agaggattgc aatagcaaga gcattagctc
    19741 ttgaaccaaa gtttttactt ttagatgaac caatgtccgc attagatgca aaggttagac
    19801 acaagcttag aatggacatt aaaagattac aaaaagaact taatataacg acaataatgg
    19861 taacacatga ccaagaagaa gctataacta tggcagataa aatagctatt ctaaatggag
    19921 gagatataat gcaaataggg actccagaag aaatatacca aaatcctcaa aacctattta
    19981 cagctcaatt tataggagat acaaactgtt ttgataatgg agattctata ttaactgtaa
    20041 gaccagaata tgttcaaata gagaaatcga caaaagaaaa ctaccaaggt ataatatcaa
    20101 atatagagtt tagagggaat ttattgagag ttgaaataaa agataaatta aatgaaaatt
    20161 tcataataag tgatgtttct ataaaagagt gggttaattt aaatttagta gaaggtgacc
    20221 ttgtaaaaat aagtatagac gaaaaatact atttaaagta tccaaaagtt aaaggagcat
    20281 aagtgtatga ataataatgc tataagttct aaaagtataa gtcttaaatc aaaaatgaat
    20341 ttagatataa aaaaatgtat gcttacagta ttagttatgt ctttagtaat atttttatta
    20401 gcacctataa tatatctatt tgtacaggct tttttagata aagatggagt ctttgtagga
    20461 ttacaaaact ttcaagaata cttggcttct gaatctctat taaattctct aaaaaataca
    20521 gtatttgtat cagttatatc aactgtaata tcactaacac ttgcattagt atatgcatat
    20581 gcattaacta gaacaaagat taaatttaaa tgttttttta aatcattagc tatgtttcct
    20641 atgtttgctc caacaatgat gcatgcaata ggtctagtat atttatttgg aaatcaaggt
    20701 ttggtaacta atttacttgg agtgcatgtt ccaatatatg gagcagtggg aataatattg
    20761 gcacaaatta tatatgtatt tcctcaatca tttcaaatac tttatatatc tctaagttca
    20821 accgattata gactatatga agctagtaat actatgggga taagcaagat aagagaattt
    20881 ataagcataa caatcccaag tataaaatac tctttaataa gttctgcatt tgtatcgttt
    20941 acattatgtt ttacagattt tggagctcca aaggtgatag gaggagagtt taatgtatta
    21001 tcaatagatg tatataagca aattataggg caacagaata tgccaatggg agcaactgta
    21061 tcaatattac ttttaatacc tgcaataata tcgtttatag taactaaaaa aattgaaaaa
    21121 aatcaaaact catatataac ttcaaagtca attccatata aggttaaaac taataagtta
    21181 agagatagta ttttaggagg ggttgtagga attattgcat ttggtataat agctgtaatg
    21241 ttaactgtaa tcttatcttc attaatatca gtttggccat atgatttaag actgacactg
    21301 gaacattttt ctatgaaaaa cagtattgat gggattaaac catttataaa ttcaataaaa
    21361 atgtcactat tgacagctat tctagggacg agctttgttt tcttatttgc atatttaaat
    21421 gaaaaaacag aaaaagctcc atatttaaaa tcatttgggt attttttaag tacattgcct
    21481 atggcattgc caggattagt tttaggtata gcttatgtat tattttttaa taaattagag
    21541 tttaatttta tggatacaat atacattaaa aatttgttta atggattata tggaacatta
    21601 cttataatgg ttatatgtaa tatagttcat ttcttttcag tagcatttat aacagctact
    21661 actgctatta agaaagtaga taaagaattg gacatggtag ctaaatcaat gggaataaac
    21721 agcgcatcaa ttcttaagaa cgtaactata ccactttgtt tgccagcagt tttagagaac
    21781 tttatgtact tttttctaaa ctctatggtg acaatatcag cactagtttt tatatatact
    21841 gcaagttcaa aagtagctgc aatatcaatt gtacaactag atgataaggg gagtactgca
    21901 caggcagcag cactagctgt gttaatatta gtcacaaata tattagtgaa agtaatatat
    21961 gaatttataa agaatcgttt agaaaaaaga acaaacttta attaaataat ttatcttata
    22021 aaaacataaa tttaaaaaag tctattcttg tgatttatta tttaaaggat agactttttt
    22081 aaattttaat taatattaat agtgttaatt ttcctttttt attatacatt tgaaaatatg
    22141 cataattata tttatcaaat aaaaagatgt ctatggaaac tttctctaaa tctaaagttt
    22201 ttggtgttac tggaagattg gttggattta gaatattatc aagctaagtt tgacaaatta
    22261 ttaagcttcg cataaaaata atgttttaat agtttttaca gttgaagttt tttataaaaa
    22321 gtttagttcc agttttaaat ttatatttat tttggttttt gcttaactta taatatatta
    22381 tattaataca tgatttttag aaataagaca caattaaata tttatatata aaattgggag
    22441 gttaaaatgg gaagagccaa atattatgat atatatatag atttaaaaaa tagaatagaa
    22501 aataaggaat atttatatca agatttatta ccatcagaat acaaattaat agaagagtat
    22561 agttgttcca gaaatacaat tagaagggct atacaggaat tagcaaacca aggatatgtt
    22621 caaagtaagc atggaaaagg agtatttata atttataggg ctaatacaca atcagaattt
    22681 ttattaggag gaacagaatc atttaaagaa tccgctatta gaaacaataa agaatataaa
    22741 acgaaagtag ttcattttga ggaaattatt atagatgata aaaaaagtca aataactaac
    22801 tttgaagttg gaacagaagt gtattatata caaagagtaa gaatattaga aaataaacca
    22861 tctattatag atcataatta ttttatgaag gatatagtaa aagatattaa tgaagaaata
    22921 gcatctaatt ctatatatga atatatggaa aatgaattga atgaaactat agtaacaaca
    22981 aaaagaacca tgacagttga aaaagcaact aaattagata aaaaatattt ggaattagga
    23041 gattataatt gtgttgcagt tgttagcaat aatacttata atgctcaagg aataatgttt
    23101 gaatatacac agtctagaca tatacctgat ggattcatat ttttccaaca atcccaaaga
    23161 attaataata taaaatagag tacaatttgt actctatttt atattattaa ttctttgggt
    23221 gttatactca taaactttag cagctaagta tatgaatgta ctagctgtcc aggtaaaaga
    23281 tttatctcta agaccttctc ctgtaatagc attgaaattt tcagcaaatc catttttatc
    23341 aactagttca cagtatcttt tggcaatatc tattgcaagt tcattttcac cgcattcttc
    23401 taaagcctca acaaataata gcgtagtagg agcccaaata ggacctctcc aataagcatc
    23461 atcttgatat tcatcactat ctatagcttc cgttgcgatt ccacatttag ttaaatatct
    23521 ttcactaata attaaatcta tcattttgtc tctagtatat ttaggaagtc tatttcctag
    23581 cactaaagaa acaagaggga gtaaagcatt attaggaagt attttaccag ttaaagtctc
    23641 acgagctaca ggtaaatcat caactataaa ataacttaag aataattttg taagctcatc
    23701 tgctttatta gcccaatact ctttttcact atatttattt agtttttcag ctacttttgc
    23761 taacatgtcc atagcattta ttataaatgc tgttaagtca ggcgtatcaa caaccatgac
    23821 tcctttaaat attgtactat tatcttgacc agaatcattt ccatgatgat attcaaaaat
    23881 accatccatg tttgaatctt taaactttat ataaaacaat acttgctttt ctatgtaatt
    23941 ataaatttcc tctaatgttt ctttagtaaa gttaattttt ttcatcattt tattaaagaa
    24001 taatccctga ataggtggtt ttgtaaaatt ccatctaata gtagaatcac ttaaagaccc
    24061 tggaatttga ccatattcat cttggtagtc gaaaagtact gccatttggt caaaagctaa
    24121 tttatcatct acaccagcta aagccaatgc gttaaaacag tgatcccaac tccatgcccc
    24181 taagaatgtt gagtttgaag caagtatagt atatctcttt aggtatcctt gaggtttaac
    24241 gaaagaagac caatttatat aactcgctct taaaagtgaa tttttatact tttcatctac
    24301 cttaggttga gctagataat attcattaaa taattttttt gtgttattta atgaagtttc
    24361 aaaattatat tccttataat ctggaacctt catatgagtg ggaatatcct ctataataca
    24421 tgtaaattca ttatcagtat tattgttaac atctattatt gaagtgttgt tagctttatt
    24481 ggtagaagca cagtcatcta taaatatatt ttgtgataaa ttaaccttac catcaacaga
    24541 gaatactaaa aacttagtta aatttttgta gctatttatc acacaatatt ctgaatcttt
    24601 tttccccata agatagttat attcaaaatt gtatacagga agtgtatcta atttaagccc
    24661 cacatttttt cccttaccat agaataagat tttagaatct ccatcaaaac atatagatat
    24721 gctaccattg ttgaatttaa ttaatatact gaaataatca gcctcaaatt cataatctac
    24781 aggtatgtta tttacagtag gtataatcct tagtacatcc atattttgtt ttgattttcc
    24841 ccttagtgat tttaatgtaa atccaagttc atctgaataa gaaatagaca tataagaccc
    24901 aaagtaacta aatggaattt cttttatatt catttgtagt atattccttt cataatttat
    24961 tttatataaa atctagcttg tttatacaag tgagtatata tttaacttac caaataataa
    25021 aataattatc aagagtcaat ttatcaaaaa aataaatagg aaactgtttt caaaaaaact
    25081 attgactaaa ttaatgcaaa atattacaat aaagttgttc aaacaagtac ttgtctaaac
    25141 aacttgctgg taatgatgaa aaaaagaaag gataaatgaa tatgaggaag aataagatat
    25201 taaattcaaa agaaagcatt tctcaaatta ttgagtatgt tgggggaaaa gaaaatatac
    25261 aaagtgcaac acactgtgta acaagattac gtttaatatt aaaagatact aacaaggcaa
    25321 acattaataa actagaaggc attgatatag taaaaggatg tttcaatgca ggtggacagt
    25381 ttcaaatagt aataggtgtc ggagtagata aagtatataa agatttaata gaacaaacag
    25441 gagcagaaga agtatctaaa gaagaaatta aacaacaagt caatgaaaag tcaaataaat
    25501 tacaaaagtt tataagagtt cttgctgata tattcattcc tatattacca gcaatagttg
    25561 catcagggtt acttatgggt gttaataaca tgatagctaa tccaggaatt ttttatgagc
    25621 agtctgtcat agaggtaaat actggtatag ctggaatttc aggtattata aatttaatag
    25681 caaacacatc atttacattt ttaccagcat taataggttg gtcagctgcc aagaagtttg
    25741 gaggaaatcc tttgttaggt gtagttttag gtcttgtatt agttcatcca gctttgatgt
    25801 ctgcatatga ttttgcggca aatccatccg cagcaccaac atgggatata tttggtatga
    25861 aggttgctca agttggatat caaggtcaag taataccagt tttaatagct acatacattt
    25921 taactaaact tgaattattc ttaaaaaaga ctgtcccaga tgcagttcaa ttagtattag
    25981 tttcaccaat agctttatta attacaggta tgttaacttt tgtagttata ggtcctataa
    26041 ctatgacagg tgcaaatatg ataactaatg gagtagtgta tttatttgaa gtagcaccag
    26101 tttttgcagg agcattatat tcatttattt caccaccatt agtaataaca ggaatgcatc
    26161 atttattctt aggagtaaac ttacaaatgg cagggacttt aggatatgta acattgtggc
    26221 caatatcaga gactgttact ttagctcaag gagctgctac attagcaatg tttttcatac
    26281 ttaaaaataa taaaaactta agaggtgtat ctattacatc tactatatca gcatggttag
    26341 gaataacaga accagctata tacggtataa acttaagatt tagatatcca tttatagctg
    26401 ttatggtagc aagtgcaata ggaggagcat ttatatcata tcacaatgtt aaagctacag
    26461 ctgttggagt tggaggagta ttttcattcc tttcagtaat gcctcaatat tggggagtat
    26521 attttacagg aatggcaata acatttgtaa taacaatcgg attaacatac ttattttata
    26581 aaagtggtaa atttaaaaca aatgacaaca tataaatata attcccttga ttttatatca
    26641 gggggtatta atatgtattg gatagatagg agacaatatg ttagatttta aaaagagtgt
    26701 agtgtatcaa atatatttaa agtcgtttaa tgatacaaca aataatggtt taggagattt
    26761 aaatggaata acagaaaaat tagattactt agaattttta ggtgttgatt atgtgtggat
    26821 tactccattt tttgtatcac cacaaaatga taatggatat gatgtagctg attattataa
    26881 tatagaccct atatatggaa ctatggatga tttggaaaat ttaataaaag aagctaaaaa
    26941 aagaaatatg ggtatcatgc ttgatatcgt atttaatcat acgtctacag agcatgagtg
    27001 gttcaaaaaa gcacttaaag gagataagta ttataaagat ttttatatat ttaaaaatcc
    27061 taaagaaggt aagagtgccc caacaaattg ggaatcaaaa tttggaggca atgcttggga
    27121 gtttgtagaa aaatttaatc aatattattt acatttattt gataaaactc aagcagactt
    27181 aaactgggaa aatcctaatg taagaaaaga attaaaaaat atactaaagt tttggataga
    27241 taaaggtata aaaggattta gatttgatgt agtaaattta atatctaaac cagagaaata
    27301 tgaagatgat ttacaaggtg atggtagaca tttttataca gatggtagaa aagtacatca
    27361 atacttaaaa gaaatgtgtg aagaaagtgg agtattggaa aatgatatgt taaccgtagg
    27421 agaaatgtct tctacgacta tagaaaactg tataaaatat tcaaatccaa atgagaaaga
    27481 attgtctatg tgttttaatt ttcatcattt aaaagttgat tataaaaacc aaaataaatg
    27541 gatgttgcaa gattgtgatt ttattaagtt aaaaaaacta cttaatgagt ggcaaatagg
    27601 aatggaaaaa ggtaatggat ggaatgcttt attttggtgt aaccatgacc aaccacgtat
    27661 aatatctagg tttggagatg ataaaaagta ttataaagaa tcggctaaaa tgttagctac
    27721 tatgatttat ttattaagag gaacaccata tgtatatcaa ggtgaagaaa taggcatgac
    27781 taatgcatac tttactaata taaaacaata tgtagatgtt gagagtttaa attattttga
    27841 tatattaaaa tctcaaggaa tgaaagatgg cgagatatac aatatattac aggaaagatc
    27901 tcgtgataac tcaagaacac ctatgcaatg gaataatagt aagaatgcag gttttagcga
    27961 atcaaaacca tggatagaag ttataaataa ttatagaaat ataaatgtag aaaatagttt
    28021 aaaagataag gattctattt tttattatta taagaagtta atagaattaa gaaaaaagta
    28081 tgatgtagta gcatatgggg attttaagcc attattagaa gagaatgatt ctatatttgc
    28141 atataagaga tgttacgaaa aagaatcttt agtagtgtta aataactttt atgataaaga
    28201 aattgatgtt attttagata atgaagagct tgaaaaatac aagtgtataa tatctaatta
    28261 tggagacaga aaagttactt caacaattac cttaagacct tatgagtgca tggctttatt
    28321 taaaaatgaa aaatagttta aaattaaaat taagaaaaat ttatgtgtac tctttaaata
    28381 aattttattt ttgatgttat aatttaatat ttattaataa ggctatgatt gtaaaaatta
    28441 tagccttatt ttaatatttt tccacatatg taaattataa tctatattaa gaaaatttaa
    28501 attatcttaa atgtatagac attttctttg tttgtatata aaattatctt attatataaa
    28561 agatttaata aggagtgaat taaatgaaag agccaattta taaagttata gaaaatcatg
    28621 ttagagagtt aataaattca gacagtttga aagaagggga tttaatccct tctgaaaaac
    28681 agttgagtga agaatttaat gtaacgagaa tgactgtaag gtctgcactt aataatctag
    28741 ttaaagaagg ctatataact agacaaagag gtgtaggtag tatagttatt gcaaataata
    28801 tatatgataa tatatcgtct gtaagtggat ttactaaaga gatggaaagt aaaggctata
    28861 aagtatctaa tatattggta tctcttgaaa tagttcaggc agatgaaaat ttatcaagta
    28921 agttgaatat aagtttagaa gaaaatgttt gggaaataaa aagagtaaga ttagccaatg
    28981 atgcaagagt ttcatatatg attacttata tgccagttaa gttatttcca aatttaaata
    29041 agactcattg tgaaaattct ctttataatt ttgttgaaga agtgtgtgga tacaagatag
    29101 ccatgtcaga gagagaagta caagctgtaa tatcgaatga agaatgtatg gataatctaa
    29161 aattagaaga accagagcca cttttatata taagccaaat ttgtaagtta caaaatagtg
    29221 agatttttga gtactcacac acatatcact atggatatac attaactttg aatgctgttg
    29281 tcgaataaaa tttaaataaa atgaaaaagt tttcttgaaa tgtatataca tttggtatat
    29341 aataatatca agaattaaat gtatatacat ttaaaaataa gatatataca ttaagaaaaa
    29401 attaatagaa aagcatattt taaatgtata gtttaaaaaa tttatgactt aaaaaatatt
    29461 taatgaatct aatttggagg ggaaaaaatg ataaaaataa tgttagcttg ttcagcagga
    29521 atgtcaacta gtttattagt tacaaaaatg gaggatgcag caaaggaaaa cggtatagaa
    29581 gcaaaaatat gggctatatc agaagtgaac ttaaaaaatg aaatagaaaa ttgtgatgtc
    29641 ttacttttag ggcctcaagt tagatatgta ttaggaaaag caactgaaat ggcaaaacca
    29701 tataatattc cagtagaagt tataaatatg atggattatg gaagatgtaa tggaaaagct
    29761 gtgttagata gagctgtaga gttaaatagt tcaaaataaa gttgtactgg aggatgtaaa
    29821 atggaaaaat tcatgtcatt tatggataaa tatatagtgc ctgtagctgc taaaatagga
    29881 gctcaaaggc acttagtagc agtaagagat gcatttatag taatgatacc tataactatg
    29941 gtaggtgcct tgggaacatt gataaataac ttaccattgg aagcatacaa aaatttgatg
    30001 gcaagtatat ttggagaaaa ttggaccaca tttggaggcg acctttggtg gggagcaata
    30061 ggtacaatgg cagtattctt agtaataggt gttgcttatt ttctagcaaa atcttatgag
    30121 agtgatgggt tacaatctgg gcttatagct ttatctatct tttttataat ggctccacaa
    30181 attggtaaaa tagttcctga gggaggaact acagtagttg aaggatgggg aatgatacaa
    30241 caaacctact taggtacagc agctttattc tcttctatat taataggatt attatcaact
    30301 gagatatttg taagattatc taaggtaaag aaattaacta taaaaatgcc agatggagtt
    30361 ccaccagcag tttcaagatc atttgcaaag ttaataccag gaatgttaac tataatgata
    30421 tttactgtaa taggaatatt tataaaaatg ctttctaatg gaagtttctt aacagatatt
    30481 ttaaatactt atttaggagc accgctatca aatgtagctg atagtctagg ttctacaatg
    30541 cttattgcat ttataattca tatactttgg actgttggac ttcatggtgc aaatatagca
    30601 cttcctttta cagaaactat acttatgaaa ttaggtggag aaaatgctgc cttggctcaa
    30661 gcaggagcaa cggaaggata ccatgtactt gcaggtgcat tctttgatgc atttgtatat
    30721 ttaggtggtt ctggaatggt attgggatta atagtagctt tattaatagc tgggagaaga
    30781 cgtaaagaaa tgatagtatt aggtgggcca cctgcaatat ttaatatagg agaaccattg
    30841 atattcggac ttccaatagt tttaaatcct atatttatga ttccatttgt acttgcacca
    30901 gtaatatgta gtgctgtatc atacttagca atagattttg gattagtagc accagtaatt
    30961 ttacctaaaa taccttgggt aacacctcct atattaggtg gagcaatggc tacaggtgac
    31021 tggactggtg gagctttagc actatttaat ttaatattat caatattaat atatattcca
    31081 tttgtcatag cgtctgaaaa aatgcaagct aataaattga aaattaacaa ctaggtagtt
    31141 ttatttcggt aaataaatgt atagagtttt aaataaatgt atagggtttt gtagagtata
    31201 ttaaattata ggtaaggatg gtataatgag atgaaaaagg gactaaaaat agttacaatt
    31261 ggaggaggtt caagttatac tcctgagctt gtagagggtt ttataaatag atatgaagag
    31321 ttacctgtaa aggaattatg gcttgtagat atagaagctg gaaaagaaaa attagagata
    31381 gttggaaatc tagctaagag gatggtaaaa aaagctggag tagatatgaa aataaatctt
    31441 actttagata gaagagaagc tctaagagat gcagactttg tgacaacaca acttagagta
    31501 ggtcttttag atgcgagaat aaaagatgaa actattcctt tatctcatgg agttatgggg
    31561 caggaaacta atggtgctgg aggtttattt aaagcccttc gcacaatacc agttatattt
    31621 gatataataa aagatgtgga agaattatgt ccaaatgcat ggatggtgaa ttttacaaat
    31681 ccaacaggaa taataacaga ggctgtattc aaatatacta attttagaag atatataggt
    31741 ctatgcaacg tgccaattca tttaaaaaat gatgttgcca aactatttaa tgtagaaagt
    31801 gacagaataa gtatggattt tgcaggtctt aatcatatgg tttatggtct aaatgtatct
    31861 ttagatggag aagatgttac aaaagaagca attgataagt ttgtcaaagc agatataagt
    31921 atgcaaaata taaaggcaat tgattttaat gctgaatttg taaaatcttt gggtgcaata
    31981 ccttgtccat accatagata ctactataaa actaaagaaa tgcttgagga tgagttgaga
    32041 gagtttaaag agggaaaagc tagaggtcaa gtagttaaag aattggaaga acaattattt
    32101 gaattatata aggatgaaaa attagatgta aaaccacctc aacttgaaaa aagaggaggg
    32161 gcttactata gtgatgctgc ttgtaattta ataagttcta tatacaacga taaaaaagat
    32221 atccaagtag ttaatacatt aaataagggc tctataagag attttaaaga tgaacaagcg
    32281 gtagaagtaa gtagtgtaat aacaaaaaat ggcccaaaac caataagtat aggatattta
    32341 ccagattctg tgcatggatt agtaagtcaa atcaaatcat ttgaagtatt ggcagctaaa
    32401 gcagctgtat atggcgatta tgaatctgct cttttggcac tttgtataaa cccattgatt
    32461 ccatctgatg acttagcaaa aactatatta gacgaaatgt tggaagctca taaagattat
    32521 cttcctagat ttaatagata gttgtctata gaaagtaggt tatggtatga ctaaaattat
    32581 aataaatgca gatgattttg gatattgtga agctgtgaac tatggaataa tttcagctca
    32641 taataatggt atagttaggt ctacttctat gatggcaaat atgcctgggg tagaacatgg
    32701 agtaggctta cttaaagaaa ataaaacttt aaattgtgga gttcatatga ctttaagttg
    32761 tggtagacca ttattatcta acttaaaaac tattgttgat aaagacggtt tttttattag
    32821 gaggattaca gacgaaatta ttgaaaaaat ggattgtgat gagatttata gagaactttg
    32881 tgctcaaata gatagggtaa aagggcttgg aatagatata tctcatttag atagtcacca
    32941 tcatatccat actttagtaa gtttaaagcc agtaatagag aagattgtaa ccaagtataa
    33001 tcttccaata agaggtggat ttgaatataa tttagagtat tctaaagtag ttcctttaat
    33061 agatagtttt tataaggaaa atgtaagtga agaatatttt ataaaaaata tagacgaaat
    33121 aatgaagtat gatgtagtgg atattatgtc tcacccagct tttttagatg attatatttt
    33181 aaattctaca tcttatgcta ttgatagaac gaaagagcac aagatactta catctaaaaa
    33241 agtcaaagaa tttttagaaa agaatggatt agtcatatca agctatagag atatttagga
    33301 ggtcgaataa atggatgaga agatgataga gatatctttt ggaataattg gatttgcagg
    33361 tgatgcgaaa gggctagcat ttgaagcaat aaaagaagca aagagcggga atatagataa
    33421 agctagagaa tgtattgaaa agtcgaaaga atcaattcat aaagctcata aattccaaac
    33481 agaattgata caaaatgaag ctaatggtaa taaaactgaa ataagtgtta tacttattca
    33541 tgcacaagac catttaatga cagctatgaa ttttcaacaa ttagcagaag aatttataga
    33601 tgtatatgaa agattagaaa gtaagtaatt taaaattatt attaaaaaag agcgtataaa
    33661 a
//
LOCUS       DACTZW010000040        31153 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.040, whole genome shotgun sequence.
ACCESSION   DACTZW010000040 DACTZW010000000
VERSION     DACTZW010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 31153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31153
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.040"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            48..2225
                     /locus_tag="JAM15_10250"
     CDS             48..2225
                     /locus_tag="JAM15_10250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HAT6798633.1"
                     /translation="MYNKYNNLYLLLGKENVNMDNYRQLKAKIPCKETGIEIKRTLCD
                     ICSPGVHCGIDAYVKDGKVIKIEGTKEHPMNKGLLCTKGLCNREYIYREDRIKTPLKR
                     IGKRGEGKFKPISWDEAYREIAEKLNRVKSEYGAKHVAFFTGYGKWYRPFLQRFASSF
                     GSPNYGTESSSCSTSAQMAGNVATGRNFTMQDMENAKTYLGWGFNPYYSKFLNSVNLI
                     KLKEKGLKFIIVDPRITPTTQKLADLHLRIKPGTDGALALGMANLFIQKDLIDREYIE
                     KHVHGFNEYKEYVKLFDLDTVSRITGVSKDNIVKAVEMLSQGPFCINESAAPIVHHQN
                     GFQNYRAMMSLSAITGNYDRIGGNIPKQDYFAGKIGGFQTLEKEFVKEVLPKNINERI
                     GGERFPLWNEMVTQFQAMDLPRQIEEKTPYEIRALFCHGINARMFPNSGRLFKALHSV
                     DFFVNIDLFMTDTSKYADILLPACTSFEREECKSYPGGYITYTKKVIDKLYDSKSDVE
                     ILSDLANVMNIDDDLLKAGYEASIRHMFKKTCVDVDKLKESDLPLKCKDFKPYIVGSY
                     TREGYDTSTSRFELKSTIIEKYKDFGLDALPTYRGFNDNIDNEYTHLLTSGARISNAL
                     HSRLHDIKLSRILKNEASCDISSLDAKEWGVISGDYIKITTKIGSLDVKVNVTDRVLY
                     KNIHMYHGYRESDINSIIDDNFDPYSGFPAYRSCKCKIEKMNR"
     gene            2239..2661
                     /locus_tag="JAM15_10255"
     CDS             2239..2661
                     /locus_tag="JAM15_10255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HAT6798634.1"
                     /translation="MKSLFKFNKELCTACGACLLACIDQNDNNIDNGELFRHVFTIEE
                     GENIEYFSLACIHCNEPKCLGVCPKNCFKKEEGFVVLDNQNCIGCKLCEKACEYGALI
                     YGNDGKANKCNGCIERYKCGMDSPCVMVCPTGALKFNK"
     gene            3068..3871
                     /locus_tag="JAM15_10260"
     CDS             3068..3871
                     /locus_tag="JAM15_10260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HAT6798635.1"
                     /translation="MKKLKLIIMLALVSALLITGCSSGNNKNKEEQKTIRVATSGTYY
                     PFAFKDKDKLKGFEVDFWDEFAKRTNCKVEWVLTDFSGLFGLLEADKADVVSAQLTAT
                     PEREKKYAFSDAYNYSGTNIIVREDDTSIKSIDDLVGKKVGVGTGAVANEILKEKYPN
                     DEIKIVNYSSATLKGNYQDLEMGRLDAVVAQDVEALIAIKEQKLNLKMVEPPIQFGAC
                     SFAIQKNEKGEKWTKEINEVIEEMHKDGTLTKISEAWLGKDITKEPINE"
     gene            3864..4532
                     /locus_tag="JAM15_10265"
     CDS             3864..4532
                     /locus_tag="JAM15_10265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAT6798636.1"
                     /translation="MSNFNFEFCLSIFPFLIKALGITILISIVAFFLSILLGVILAFF
                     TQTKSKVLQYITRVYVSFFRGTPLLIQIFFFYFGFPMIFSFMKDCSPYLAIVICLGVN
                     SSAYMTEIIRASIESVDKGQQEACYAFGLSKYQSMVKIILPQAATSAVPPIVSCTLDI
                     IKGSSLGLTIGIQDLMGVAQVEAASSFKYFEIYMITILIYWAVSIILSNIQSKVEKRI
                     GKAY"
     gene            4768..5430
                     /locus_tag="JAM15_10270"
     CDS             4768..5430
                     /locus_tag="JAM15_10270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAT6798637.1"
                     /translation="MIFNMKYFLELFPIIMKSFNVTVILAISSLVFSLIIGTIVALSS
                     YYKVKVLNQICKVYVSIFRGTPLMPQLFFLYFGLAYMNDFVKNMDPVFATSIVLSLNM
                     GAYMSETIRASILSIDKGQIEAAYVMGLTNLQTMKRIVIPQAVRVALPSLFNNFIDLI
                     KGSSVAFVVGVNDIMGAAKSQGALSFKFFEVYGAVMVIYWCIITPLGWGQKKLEKKIS
                     NY"
     gene            5490..6287
                     /locus_tag="JAM15_10275"
     CDS             5490..6287
                     /locus_tag="JAM15_10275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HAT6798638.1"
                     /translation="MVKRNIIKCLVAVLSLTFVVAGCSKKEEVKDEKVITVASSNSAD
                     PYSYVDNGEHKGFEVDMWKEIGKRSGYKIKMEPTGFSSIFGMLDSGKVDVAANFFGMS
                     KERLEKYDASIPYGSDSVCIAVKDGNNEINKLEDLKGKVVAVSEGSQGQQVAASVNKD
                     NLFEEKVYGDGTNGLQDLDLGRVSAWIDAELTVVGDAKKANMKVRVLDEKLSVTNIAY
                     FFKKNDEKSKTIKEDVNKAIEEMLSDGTVKKISEKWFGMDVSADIQK"
     gene            6420..7595
                     /locus_tag="JAM15_10280"
     CDS             6420..7595
                     /locus_tag="JAM15_10280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HAT6798639.1"
                     /translation="MIETKIKSIALKNREKIIKIRRQIHSNPELAFKEFKTSKLIKEE
                     LNKLKIEYIDVAGTGVLATIKGKNNGGKTILLRADMDALPIKEENDLEFKSINDNMHA
                     CGHDAHVSWLLGTAMILNDIKEELNGNVKLLFQPGEEKGGSDIVIKENVLEGVDALAT
                     GHCWPTIESGKIGIARNCAMAATNTFEITIIGKGGHGAEPHNCIDPIAVGNAVYSSIQ
                     QIVSRKIDPVVPVVVSVCSFNSGVSKNIIPDVCTLQGTIRAISKEQVIEVSKILENIV
                     RNVCRAYGADCKFEKSTGGDAVINDKNMIELGRESACKILGVENVEIIDFPAMTGEDF
                     AIYMKEKPGLFMYIGVGNKEKNINYRLHSNKFNIDEKCLSIASSLFSQLAVDYLCQL"
     gene            7704..8453
                     /locus_tag="JAM15_10285"
     CDS             7704..8453
                     /locus_tag="JAM15_10285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAT6798640.1"
                     /translation="MIKVENLHKSFKGTEVLKGINLEINQSEVVAILGPSGTGKSTLL
                     RCLNYLVEPTKGKIMIGDVKVDVEKATKKDIANLRKHTSMVFQNYNLFKNKTALENVM
                     EALIVVHKKSNKEAREISLKLIDKVGMLDRKDFYPSKLSGGQQQRIGIARAMAVNPNV
                     ILFDEPTSALDPELVGEVLSVIKSLAKEGITMLIVTHEINFAKEVADKIIFMDNGVIA
                     EEGTPDEIFNNPKNERTAKFLNIVRKEEVFS"
     gene            9045..10106
                     /locus_tag="JAM15_10290"
     CDS             9045..10106
                     /locus_tag="JAM15_10290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HAT6798641.1"
                     /translation="MRDFLKNYKSSIILLACTIIGAIVGLVLGPKASILKPFGDLFIN
                     ALLMIVVPLVFLSVSSGVASIKNMERFGKIMKSTAIVFMGTTLVIAFLGITSALLFNP
                     SKGLDVSSVKSLMVAQDAETLESKGTLLDQVVSSITVKNFGDLFSSSNLLQLVIFAVL
                     VGTAIAMMGDRGNTIRKFLSEGTEAILKVVSIVMLYAPIGLGCYTATIIGELGSKIIQ
                     GYVRVFVIYSLTAAMYFLLFYSLYAFLSAGKQGFRQFWRNAIKPIATALATSSSSACI
                     PSNLEASKNIGVPDDISETVIPLGINIHKDGSVLAVIIKVAFLSGILGSGMANPATIG
                     QLFITVFVVGVFMAPVAGG"
     gene            10119..10316
                     /locus_tag="JAM15_10295"
     CDS             10119..10316
                     /locus_tag="JAM15_10295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HAT6798642.1"
                     /translation="MLVVSIFGFPVEAIPLLTVITTITDIPNTILNTTGNTVSSMLVS
                     RLVEGKDWLIDKTAITTKKIS"
     gene            complement(10480..11208)
                     /locus_tag="JAM15_10300"
     CDS             complement(10480..11208)
                     /locus_tag="JAM15_10300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAT6798643.1"
                     /translation="MKTNYRLHMQQGSDYLKKFLEKHIDLLKKIPLFEGIKSDELEEM
                     LECLGVVDKTYPKDSIIFSVGSEVTSIGIMLKGSAHIIKEDIEGNRNIVAELLPGDLF
                     GEVFACTRLHKSNVTVTTTSSCEVLFIKFKSVTGICSSACVFHNRLVENMLQLIAEKN
                     ILLHNKIELLSRKTTREKLLMYFSKQIEQTGSHQFTIPFSRNEMADFLCVDRSSMSRE
                     LGKMRDEGLLSFNKNKFEIFYFQK"
     gene            11349..12074
                     /locus_tag="JAM15_10305"
     CDS             11349..12074
                     /locus_tag="JAM15_10305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S ferredoxin"
                     /protein_id="HAT6798644.1"
                     /translation="MMRKIIKIDEGKCNGCGLCVEACHEEAIGMVNGKAKLLRDDYCD
                     GLGDCLPTCPTNAISFEYREAAEYDEAAVKANMEAKKAQKKTLACGCPGSQSKSINRE
                     VSNSTSISNDIVEIKGSQLNQWPVQIKLVPTNASYLKNASLLIAADCTAYAYGNFHNK
                     FMKNKVTLIGCPKLDEVDYAEKLTEILKENDIKNIVVTRMEVPCCGGIVNAVKTALQN
                     SGKMIPWQIVTISVDGKIVDGEI"
     gene            12134..13726
                     /gene="hcp"
                     /locus_tag="JAM15_10310"
                     /gene_synonym="priS"
     CDS             12134..13726
                     /gene="hcp"
                     /locus_tag="JAM15_10310"
                     /gene_synonym="priS"
                     /EC_number="1.7.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014312828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxylamine reductase"
                     /protein_id="HAT6798645.1"
                     /translation="MEKMFCFQCEQTAGGKGCTINGVCGKKGGTANLQDELTGVLIGL
                     SRATIGNKNRPTSETDKIMIEGLFTTITNVSFDDEAIKRQIEKTEVEKSKLVPRCSDC
                     STTCNRNDNYDMKDLWNDNEDIRSLKSLILFGLRGMAAYAYHAMVLGYTDKDVNEFFY
                     EGLIAVGGDLSIDELLGLVMKTGEINLKCMELLDRANTETYGTPEPTQVSMKIEKGPF
                     IVVTGHDLYDLHKLLEQTKDKGINIYTHGELLPAHAYPKLKEYKHLKGNFGTAWQNQQ
                     KEFDNIPAPILFTTNCLMPVKDSYRDRVFTTEVVAYPGMVHIDEDKDFSSVIEKALEL
                     GGYREDVHMTGINGGDTLTTGFARGTVSSVQDKVVDAVKSGAIRHFLFVGGCDGAKPG
                     RNYYTEFVKQAPKDTVILTLACGKYRFNDLDLGDIGGLPRLMDMGQCNDAYSAIKVAV
                     SLANAFECGVNDLPLSMVLSWYEQKAVCILLTLLHLGIKNIYIGPSLPAFLSKNVLDI
                     LVDKFALTPISTPEEDMKKILG"
     gene            14090..14995
                     /locus_tag="JAM15_10315"
     CDS             14090..14995
                     /locus_tag="JAM15_10315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin"
                     /protein_id="HAT6798646.1"
                     /translation="MKSSNFNILAFDGGGLKGALSISILERIVKEYPNLLNNINMFGG
                     TSTGSLIALGLAYGVSPKEIKELYSIENSKYIFNKSYAEILRPKYENKNLKEVLLSIF
                     PEELELKDLNKLVMIPSFYIGNEENAWKPVFYNNMSNSFTKTSKVVDVAMASSAAPVF
                     FPTYNRHVDGGIIATDPSLACIIHAIDSGFKLKNTRLFSIGTGYVYNSIKADTTEWGA
                     IDWIINKEPDLPIISITLEGNSQMSQLFSQKLLGDNYYRLNPKMEKDVAMDDCDALEY
                     LMSLGENCDIKDAFGWIKKKSFYRN"
     gene            15119..16072
                     /gene="msrA"
                     /locus_tag="JAM15_10320"
     CDS             15119..16072
                     /gene="msrA"
                     /locus_tag="JAM15_10320"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002844031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAT6798647.1"
                     /translation="MIKLATFAGGCFWCMVKPFDKYDGVIKVVSGYTGGHVENPTYQE
                     VCSGTTGHLEAIQITYDDDIISYDELLNIFWKQINPTDDGGQFGDRGTQYKTAIFYHD
                     EEQKNIALESREHLENSKIFDSKIVTDIIPATKFYEAEENHQDYYKKRPLNYNMYYKG
                     SGRYNFVKSHWDGNNINREELKKTLTPIQFEVTQNDMTEVPFENEYYDNNKEGIYVDI
                     VSGEVLFSSKDKFDSGCGWPSFSKPVIDKSIIERSDFSQGMYRVEVRSAKGNSHLGHV
                     FDDGPKELGGLRYCINSASLKFIPRENMEALGYGEYLKLFE"
     gene            16225..17355
                     /locus_tag="JAM15_10325"
     CDS             16225..17355
                     /locus_tag="JAM15_10325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAT6798648.1"
                     /translation="MNLKDFNGKRLKSARIFRAKTIEQLSKETKINKKDLKAFEENKY
                     VPNIENTLKLSNILNFPKEYFYKNENINIVVEDSHFNPQSKLPRVEEISYREKIIIIH
                     KIYSFMENYIKFPKENLPNRKVMSDININDIESLAYKTREFWDLNSTPIVNMVSLLES
                     KGIIISGMNVDRKGATIFTQKQRISKESKYLISLGNDKKSASIRNYTLACELGYIISS
                     ELRIPSKQFSEDEYACAFLLPKESFLKDLTHPEDLDYYVELKKKWIVPISAMIFRAYN
                     LEKINYKKYNYLMNEMDKKGWLIEEPLDKMKGSSPTYLKRAVELLIENKIMSVNSIVS
                     SLEEFGINLYPEDLELLMGLKKGLLSQEVNKKSKVIKFDGKK"
     gene            complement(17472..18440)
                     /locus_tag="JAM15_10330"
     CDS             complement(17472..18440)
                     /locus_tag="JAM15_10330"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HAT6798649.1"
                     /translation="MAIKPRKISIVGSGHVGSHCGFSLITQGVCDELFMIDIDESKSK
                     AQALDLADAVSYLPHKVHIEKGTFSDCKDSDIVVISVADSSEGPLRRQNTTRLDLLRP
                     TIGMIKSIVKPIVDSGFDGIFVVISNPVDVVTNYIWEKSGFPKNKVIGTGTALDSTRL
                     RRILSEETGIAQQSIQAYSMGEHGDSQMVPWSHVSIGGKPILDVIKDNPSTYSNLDLP
                     SIVEKNKKTGISIINGKDCTEFGIGTALVEIVKAILHNEKKVLPVSTLLEGQYNERNV
                     FAGVPCVIGKDGIEEIIEINMTEYEQNEFNKSCSVLREYIALSKTL"
     gene            18775..18963
                     /locus_tag="JAM15_10335"
     CDS             18775..18963
                     /locus_tag="JAM15_10335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798650.1"
                     /translation="MNYHTKEELMEVLRVASSRIINCEKVQKKFSEETSHHTRFKNII
                     EAMYISKSLIMDEISKRD"
     gene            19223..20422
                     /locus_tag="JAM15_10340"
     CDS             19223..20422
                     /locus_tag="JAM15_10340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanyl-tRNA editing protein AlaX-L"
                     /protein_id="HAT6798651.1"
                     /translation="MEKLYYTNQYIRDFTAEIIEIKEVENKYHVLLDKTTFFPGGGGQ
                     FGDLGKIENDDVINVYEDGKNIYHVLDKKPIKIHKVKCSIDWDRREDGMHQHFGQHVL
                     SGCFFKTFNANTTGFHLGNEYSTVDIEGNLEENKIREIELFANEIIRQNIQVETLLPT
                     KKELKKIWLRRDLPNTDEEIRVIKIGDLDTNACCGVHPKSTGELRMIKIKKWEKHKSS
                     TRIEFLAGKRAVDEVLKRDIYLTKICRYLSCSEEDAINGIVNLNSKVEEALIKKRRLE
                     EVVSTYQVKEMIEKANKVGNISVIKKIYDDEDLKYVNKIANKIAEYENSIALLAVKFN
                     DKINLVFACSKNLKDINMGVLLKDAISLIDGKGGGSKVLAQGGGKNNGNLEATLDYAF
                     MKIEKTL"
     gene            20474..20977
                     /locus_tag="JAM15_10345"
     CDS             20474..20977
                     /locus_tag="JAM15_10345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAT6798652.1"
                     /translation="MEQQKDYIELYENEELIEIREARMDDLDTIAKFNYNLAKETEGK
                     ELDMDVLTKGVKALLLDERKGKYHVYTVFDKVVAQIMYTYEWSDWRNGNFLWIQSVYV
                     DKEYRRKGIFNYLFNYIKNICDKDENIVGMRLYVEKENINAKATYESLNMHECDYNMY
                     EYEVIHS"
     gene            21084..21401
                     /locus_tag="JAM15_10350"
     CDS             21084..21401
                     /locus_tag="JAM15_10350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798653.1"
                     /translation="MGVLKGMFYVFLFLDLVSIFCFFFNKGKIASNKIVFNAIGVLTF
                     VLCFMLFSYYPNNNLIGKFIASLFFIFGVAGVMLKEKNFLYARLLLTVVIVFSTLRLF
                     VIQ"
     gene            21559..22503
                     /locus_tag="JAM15_10355"
     CDS             21559..22503
                     /locus_tag="JAM15_10355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAT6798654.1"
                     /translation="MIESKKSEKLLLSIIYIIFLVYILMIIRIILFRDVPIYAIFKGT
                     FRTVNLIPFYTIYQFIVDSNLDFMKATVNIIENIGIFIPMGIFLPIVCKNLNKKTIII
                     AIIFVSLAFELTQYIFALGSSDIDDVILNSLGGIIGINIYINMNKLFPNDIKRFKAII
                     ATSLVLGVISKNYHNLLTFKFRPDRKISKILIEENREIIKDINKDTVDIVGTFESFKK
                     GIITIKAGSNNKVKRPENLIDSDGNIRIYLNENTKLVSYIITKESKMDIVKYEEFDVK
                     NLDLLRRYDTINVWIDKENQPKDKHGIMASKLLIGLYE"
     gene            22618..23403
                     /locus_tag="JAM15_10360"
     CDS             22618..23403
                     /locus_tag="JAM15_10360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798655.1"
                     /translation="MEIIKYILYFFIYSFLGWTVESIGCSIASKRIINRGFLNGPICP
                     VYGFGAVIVISLLGRFNNVVIVFLLGMILTTILEYFTGFILETLFHAKWWDYSDRKFN
                     IKGRVCLKNAIYFGVMSVLIIRFIHPFIKYFVSIIPYRILISMAIITTLWTILDLIVT
                     IITLKKLDIKLNLLDDIITDLNDINVKLDKFDRGEIQALFKTINNDELEVREKINKIN
                     SKLDRIESNIILQKRVIKAFPHIKHKKQQEQLEHFKKIINEKR"
     gene            23695..25014
                     /locus_tag="JAM15_10365"
     CDS             23695..25014
                     /locus_tag="JAM15_10365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class III-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HAT6798656.1"
                     /translation="MSEITSQMISTEEKKYVAKTQKIPYYPVAFKSGDGAMLYDYEGN
                     EYVDFLASAGSANVGHGNKEISQAVKEQMDDITQYTLAYFHSDPPVKLAEKLVEIAPG
                     DNDKKVLYSATGSACIDAAIKLARGYTGRTKIISMCESYHGSTYGAISISALSTNMRR
                     KMGPLLPEVYHFHYPDKNRTAKECLDEIEYAFAHYLPAEEVAAIFIEPIAGDAGIIVP
                     PVEWVQGLSKICKENGILLVSDEIQQGMGRTGKWFGIENFGVEADLIVLGKSVGGGLP
                     LGAVVGRTEIMQSLDAPAHLFTLAGNTTVCVAALKSIEIIEKENLLQKSIEMGDYIKA
                     GFEKLKEKYDIIGEIRGIGLSIGVDIVKGKGSNEKHPDATAKICYRCIQTGLIMIFLG
                     QSTLRVQPPLVITKEQVDKAMSIIDSAIDDYLNGRIGDEVYEVTQGW"
     gene            complement(25089..25517)
                     /locus_tag="JAM15_10370"
     CDS             complement(25089..25517)
                     /locus_tag="JAM15_10370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798657.1"
                     /translation="MKDNNNTNKTIQFGEKKASLENNIQKNKNIKLDNTHKVIPYPKN
                     RKKDDKKKGNKKKNTNTSKVNKNNYGHSFFNNKYKYKRKPYVIALYTVILILLAILII
                     TKLTDSTNKGNYSRNTVSDTHKNDIRNIVFNESNNFLICG"
     gene            complement(25608..26984)
                     /gene="hydG"
                     /locus_tag="JAM15_10375"
     CDS             complement(25608..26984)
                     /gene="hydG"
                     /locus_tag="JAM15_10375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014094795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydG"
                     /protein_id="HAT6798658.1"
                     /translation="MFINHELINSLLEDAKNSTSDDIEKVLDKADRREKLSYKDIATL
                     LEVEDKKQLDRLFSIAGQIKNEIYGNRVVLFAPLYVSNYCVNECVYCGFSKCNKFKRK
                     KLTMEEIKEEVKILEKMGHKRLALEAGEDPKNCDINYILDCLDAIYSTYNENGNIRRV
                     NVNIAATSVDEYKLLKEKGIGTYILFQETYHKPTFIKMHGQSIKNDYYYHLTAFDRAM
                     EAGVDDVGAGVLFGLSDPKFEVLGLMMHNEHLEEKFGVGFHTISFPRLKKAEGMSLED
                     FPHLVSDDMFKKIVAITRLAVPFTGIIMSTRETAEMRNELLKYGVSQISAGSLTGVGG
                     YKAYEDGDNTEQFEVGDHRSPVEVLKELITDGYIPSYCTACYRKGRTGDRFMSLAKSR
                     QIHNVCTPNALTTLNEFLIDYGDEELKIMGKKLIAEEIGKIEREDIRNIVSNNMTALE
                     RGERDLYL"
     gene            complement(26985..28070)
                     /gene="hydE"
                     /locus_tag="JAM15_10380"
     CDS             complement(26985..28070)
                     /gene="hydE"
                     /locus_tag="JAM15_10380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydE"
                     /protein_id="HAT6798659.1"
                     /translation="MTKNKIKYFIDKLYSINSLSFDELLYLIENIDNEEYNFEQNLRN
                     YLYKQASDMRNKHYGNRVYLRGLIELTNYCKNNCYYCGIQSSNKNIIRYRLSPDEILE
                     CCDIGYKIGYRTFVLQGGEDAYFTDDKICEIVSSIKNKYEDCAITLSLGEKSYDSYKK
                     YFLCGADRYLLRHETATDSHYKKLHPPNIELRTRKECLKNLKEIGYQVGAGFMVESPF
                     QNNEDLVRDLLYLKELNPHMVGIGPFIPHHDTIFKDYKHGDLEKTLLMLSITRLLLPK
                     VLLPATTALASINPSGRNAGLLAGCNVIMPNLSPQEFRKQYSLYDNKAFTGQEACEYH
                     QSLEENIKSLGLEVDYSRGDNIEWRRL"
     gene            complement(28106..29314)
                     /gene="hydF"
                     /locus_tag="JAM15_10385"
     CDS             complement(28106..29314)
                     /gene="hydF"
                     /locus_tag="JAM15_10385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster maturation GTPase
                     HydF"
                     /protein_id="HAT6798660.1"
                     /translation="MSLNSTPQSVRVHIGLFGKRNAGKSSIINAITNQSAAIVSDIAG
                     TTTDPVFRPMEILPIGPCVLIDTAGLDDVGELGELRIGKSLDVLEKTDIALLVVDCQI
                     GISQEDLSLIEKFNDKNIPHILILNKIDTIKNQSEILNLTKNKVKCPVVSVSSTDKIG
                     IENLKNEIIKVLPKDSTEFKLVSDLIEPNDLVVLVVPIDKAAPKGRLILPQQQVIRDI
                     LDNGAISIVTKEDSLKETLSNLGKKPKLVITDSQVFPQVNKDTPKDIPLTSFSILFAR
                     QKGDLKELINGAYALENLKDGDKILMAEGCTHHRQTDDIGTVKIPNMIRKKTGKNITF
                     EFSSGVSFTEDINKYALVVHCGACMMNRAGMLSRIEKAKSFNVPIVNYGILIAYVKGI
                     LERSLELFNY"
     gene            complement(29329..29580)
                     /locus_tag="JAM15_10390"
     CDS             complement(29329..29580)
                     /locus_tag="JAM15_10390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019279311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-only hydrogenase system regulator"
                     /protein_id="HAT6798661.1"
                     /translation="MKKVAVISAILEEPKECQFKFNEVVSGFKGIIKGRMGIPCEEEG
                     VSIVCIAVVGEMDTINSLTGKLGNIPHVSVKTSISKKEV"
     gene            complement(29961..31001)
                     /locus_tag="JAM15_10395"
     CDS             complement(29961..31001)
                     /locus_tag="JAM15_10395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HAT6798662.1"
                     /translation="MNLNLTNTINLMKKYLDIPSPAGYTENAVLESKKDFENLGLDTI
                     LTKKGALIATLPGEDDSNQITISAHMDTLGAIVKEISSDGTLKYHKVGGGCWAAIEGE
                     NCTVITRKGKKIRGSVVFKYASTHIYGQTKAATERNEETMIIRLDEKVFTKQDVLDLG
                     ISVGDFVCLDHRFEATESGFIKSRYIDNKSAVAMVLEICRYFKENNLTPKHTTNFYIS
                     NYEEIGHGVSKCLPEKTKEFVAIDIAPTGPSQTSSEHGVTIVAKDNLSLYDFNLRNKL
                     VDVAEDNNLDYAVDVFTFYGSDASEAIRWGEDVQIACVGPGTNNSHHYERTHIEAIEN
                     TLKLLINYMLKE"
BASE COUNT        11888 a         3562 c         5166 g        10537 t
ORIGIN      
        1 gaaattgcac tatataaaat ataaagtatg atatttgaat aaaaagaatg tataataagt
       61 ataataattt gtatttatta ttgggaaagg aaaatgttaa tatggataat tatagacaac
      121 ttaaagctaa aataccctgt aaggaaacag gtatagaaat aaagaggact ttatgtgata
      181 tttgttctcc aggagtacat tgtggaattg atgcatatgt taaagatggt aaagtaataa
      241 aaatagaagg tacaaaagaa catccaatga ataaagggtt gttatgtacc aaaggtcttt
      301 gcaatagaga atatatatat agagaagata gaataaaaac acctctaaaa agaattggaa
      361 aaagaggtga aggaaaattt aaaccaatat catgggatga agcttataga gaaatagcag
      421 aaaaattaaa tagagtaaaa tctgagtatg gagcaaagca tgtagctttt tttacgggtt
      481 atggaaagtg gtatagacct tttttgcaaa ggtttgcatc ttcatttggt tcacctaatt
      541 atggtacaga atctagttca tgttcaacat cagcacagat ggctggaaat gttgctactg
      601 gaagaaactt tacaatgcaa gatatggaga atgcaaaaac ttatttaggg tggggattta
      661 atccatacta ctctaaattt ttaaatagtg tgaatctaat aaaattaaaa gaaaaaggtc
      721 taaaatttat aattgtagac cctagaataa caccgacaac tcaaaaacta gcagatttac
      781 atttaagaat taaacctgga actgatggag ctttagctct tggaatggcg aatctattta
      841 tacaaaagga tttaatagat agagaataca tagaaaagca tgtacatgga tttaatgaat
      901 ataaagaata tgtaaaatta tttgatttag atactgtaag tagaattaca ggagtttcta
      961 aagataatat agtaaaagct gttgagatgt tgtcacaagg tccattttgt ataaatgaaa
     1021 gtgcagctcc aatagttcat catcaaaatg gatttcaaaa ctatagagca atgatgtctt
     1081 tatctgctat aacaggtaat tatgatagaa taggtggaaa cataccaaaa caagattact
     1141 ttgctggtaa gataggtgga ttccaaacac tagaaaaaga gtttgtaaaa gaagttctac
     1201 ctaaaaatat aaatgaaaga attggtggag aaagatttcc tctatggaat gaaatggtga
     1261 ctcaatttca agctatggat ttacctaggc aaatagaaga aaagacacca tatgaaataa
     1321 gagctttgtt ttgtcatggg ataaatgcta gaatgtttcc taattcaggg agacttttta
     1381 aagcgttaca tagtgtagat ttttttgtga atatagattt atttatgaca gatacatcaa
     1441 aatatgcaga tatactttta cctgcgtgta catcatttga gagagaagaa tgtaagagtt
     1501 atccaggagg gtatattaca tataccaaaa aagttattga taaattatac gattcaaaat
     1561 cagatgtaga aatactttca gatttagcaa atgttatgaa tatagatgat gatttattaa
     1621 aagcaggtta tgaagcaagt ataagacata tgtttaaaaa gacgtgtgta gatgtagata
     1681 aacttaaaga aagtgattta ccattaaaat gtaaagattt taagccatat atagtaggct
     1741 catatacaag agaggggtat gatactagca cttctaggtt tgaattaaaa tctacaatta
     1801 ttgaaaaata taaagatttt ggactggatg cgctaccaac atatagagga tttaatgata
     1861 atatagataa tgaatatact catttattga catcaggagc aagaatttca aatgcactac
     1921 attcaagact tcatgacatc aaactttcaa gaatattaaa aaatgaagct agttgtgata
     1981 tttccagctt agatgcaaaa gaatggggtg ttatcagtgg agattatata aaaataacta
     2041 ctaagatagg aagtttggat gtaaaagtca atgttactga tagagtctta tataagaata
     2101 tacatatgta tcatggatat agagaatctg atataaatag tattattgat gataattttg
     2161 acccttatag tggattccct gcgtatagaa gttgcaagtg taagattgaa aaaatgaata
     2221 gataaatgga gagatataat gaaaagttta tttaaattta ataaagaatt atgtacagca
     2281 tgtggagcat gtttgcttgc atgtatagac caaaatgata ataatataga caatggtgaa
     2341 ctttttagac atgtatttac aatagaggaa ggtgaaaata tagaatattt ttcattagca
     2401 tgtatccatt gtaatgagcc aaaatgttta ggtgtatgtc ctaaaaattg ttttaaaaaa
     2461 gaagaaggat tcgttgtatt agacaatcaa aactgtatag ggtgtaaact ttgtgaaaaa
     2521 gcttgtgaat atggagcctt aatttatgga aatgatggta aggcaaataa gtgtaatggt
     2581 tgtattgaga gatataagtg tggtatggat tcaccttgtg taatggtatg tcctacagga
     2641 gcattaaaat ttaataaata aattaaatat agagagtgac ttatacttgg tataagatat
     2701 ttttacaaaa agctatattg agtttgttat aataaaaact caatatagct tttttatgga
     2761 tatagttgga tactataatg tgatttttag taatagtttt ttgctattgg acaaagactg
     2821 taaaacatat taaacttatg ttgttcaaag tcgaagtata atataataac tagaaaattg
     2881 atttatagtg ttataaaagc aaatttagta aggtataaaa tcagaggcaa tcttttacta
     2941 cagtatcaat atttgggagt tatgttatgg cagagccatt aaacaattat aatggtacaa
     3001 gtgattcaac ctttgaaaat gtattatata aaaaattaaa ataagattaa aaaggagaga
     3061 ataaattatg aaaaaactta aattaattat tatgcttgcc ttggtatcag cacttttaat
     3121 tacaggatgt tcatcaggaa ataataaaaa taaagaagaa caaaaaacta taagagttgc
     3181 aacatcagga acatattacc cttttgcttt taaagataaa gataaactta aaggatttga
     3241 agtagatttt tgggatgaat ttgctaaacg aactaattgt aaagttgaat gggtattaac
     3301 tgattttagt ggattatttg gattattaga agctgataaa gcagatgttg tatctgctca
     3361 acttactgca acacctgaaa gagagaaaaa atatgctttt tcagatgctt ataattatag
     3421 tggaacaaac attattgtta gagaagatga tactagtata aaatcaatag atgatttagt
     3481 tggcaagaaa gtaggtgtgg gtactggagc agtagcaaat gaaatactaa aagaaaagta
     3541 cccaaatgat gaaataaaaa tagtaaatta ttcaagtgca actcttaaag ggaattatca
     3601 agatctagaa atgggaagat tagatgcagt agttgcgcag gatgttgagg ctttaatagc
     3661 tataaaagaa caaaaattaa atcttaaaat ggtagaacct ccaattcaat tcggagcctg
     3721 ttcttttgcg attcaaaaaa atgaaaaagg tgaaaaatgg acaaaagaaa ttaacgaagt
     3781 aattgaagag atgcataaag atgggacttt gactaaaata tctgaagcct ggctaggaaa
     3841 agacattact aaggagccta ttaatgagta attttaattt tgaattttgt ctaagtatat
     3901 ttccattttt gattaaagca ttgggaataa caatactaat atctattgtt gcattttttt
     3961 tatcaatatt attaggtgta atacttgcct ttttcacaca gacaaaatca aaagttttgc
     4021 aatacataac aagagtgtat gtttcattct ttagaggaac accactttta attcaaatat
     4081 ttttctttta ctttggattt ccaatgatat tttcttttat gaaagattgt tcaccttatt
     4141 tagcaatagt aatttgttta ggtgtaaatt catctgcata tatgactgaa attatacgag
     4201 catctattga gagtgttgat aaaggacaac aggaagcatg ttatgctttt gggttaagta
     4261 aatatcagtc aatggttaaa ataattctac ctcaagcagc tacatctgca gtacctccta
     4321 ttgtaagctg tacactggac ataattaaag gttcttcttt aggtctaact ataggaatac
     4381 aagatttaat gggagtagct caagtagagg ctgcttcaag ttttaaatat tttgagatat
     4441 atatgataac gatattaatt tactgggcag tatctataat attgagtaat atacaaagca
     4501 aagttgaaaa aagaatagga aaggcatatt agatttcaat atttaaaaat gggatgatgt
     4561 agatatatta ttacttgtaa ataaattttt aattttagaa aaataaactt agtaatctaa
     4621 attattgaga aaatatagta tcaaaatgga ctgtataatc aagttaaaaa atagtttttc
     4681 tattgaaaaa ataaataaaa ttctattgta atttaatatt cgacaaagtt ttataaaaaa
     4741 caacattaag ctagggggac ttattttatg atttttaata tgaaatattt tttagaatta
     4801 tttccaataa taatgaaatc gttcaatgta actgtaattt tggcaataag ttcattagta
     4861 ttttcattaa ttataggtac aatagtagca ttatcatctt attacaaagt gaaagtattg
     4921 aatcaaatat gtaaagtata tgtatctatc tttagaggta cgcctcttat gccacagtta
     4981 ttctttttat attttggact agcgtatatg aacgattttg ttaaaaatat ggacccagta
     5041 tttgcaacat ctatagtact tagtttaaat atgggagctt atatgtccga aacgataagg
     5101 gcatctatac tttcaattga taaaggtcag atagaagcag catatgtaat gggattaaca
     5161 aatttacaaa caatgaaaag gatagtgata ccacaggccg taagagttgc actgccatca
     5221 ttattcaata attttataga tttaattaaa gggtcttctg tagcttttgt tgttggagta
     5281 aatgatataa tgggtgctgc caaatcacaa ggagcgttga gttttaagtt ctttgaagtg
     5341 tatggagcag ttatggtaat ttactggtgt ataataactc ctttagggtg ggggcaaaaa
     5401 aaattagaaa agaaaataag caattattaa gttattaaga aaatacataa aagtattttt
     5461 atataaaaaa tggtgtgagg agaagagata tggtaaaaag aaatattata aaatgtttag
     5521 tggcagtttt atcgttaaca tttgtagttg ctggttgttc aaaaaaagag gaagtaaagg
     5581 atgaaaaagt tataactgta gcttcatcta attcagctga cccatattct tatgttgata
     5641 atggtgagca taagggtttt gaagttgata tgtggaaaga gattggtaaa agaagtggat
     5701 ataagataaa aatggaacca acaggtttta gttctatatt tgggatgtta gattctggta
     5761 aagttgatgt ggcagccaat ttctttggaa tgtctaaaga aagattagaa aaatacgatg
     5821 cttctatacc ttatggttct gattctgtat gtatagctgt aaaagatgga aacaacgaaa
     5881 ttaataaact tgaagattta aaaggaaaag ttgtagcagt ttcagaaggt tctcaagggc
     5941 aacaggttgc agctagtgtt aataaagata atttgtttga agaaaaggtt tatggtgatg
     6001 gaactaatgg tcttcaagat ttagatttag gaagagttag cgcatggatt gatgcagaac
     6061 ttactgttgt aggagacgct aaaaaagcta atatgaaggt aagagtatta gatgaaaaat
     6121 tatcagttac taatatagca tacttcttta agaaaaatga tgaaaaatct aaaactataa
     6181 aagaagatgt aaataaagca atagaagaaa tgctttcaga tggaacagtg aaaaaaatat
     6241 ctgaaaaatg gtttggaatg gatgtaagtg ctgatataca aaaataaata ctttaaaatt
     6301 aaaatataaa actgtgataa ctatagataa gtatactaaa tttatctata gttatctgtg
     6361 tattacaatg tatttagatt agtctttata aattaaaatg agttatggag gtcttgcaaa
     6421 tgattgaaac taaaataaaa tccattgcac taaaaaatag agaaaaaatc ataaaaataa
     6481 gacgacagat acacagtaat ccagagttag catttaaaga atttaaaaca tccaaactta
     6541 taaaagaaga gttaaataaa cttaaaatag aatacataga tgttgctggt acaggagtat
     6601 tagctactat aaaaggaaaa aataatggtg ggaaaactat attgcttaga gcggatatgg
     6661 atgcccttcc aatcaaagag gaaaatgatt tagaatttaa atcaataaat gataatatgc
     6721 atgcttgtgg gcatgatgcc catgtttcat ggttgttagg aacagcaatg attttaaatg
     6781 acataaaaga agaattgaat ggaaatgtaa aattactatt tcaacctggc gaagaaaaag
     6841 gtggttctga tattgtaatt aaagaaaatg tacttgaagg tgtggatgca ttagcaactg
     6901 gtcattgttg gccaactatt gaatcaggaa aaattggaat cgctagaaat tgtgctatgg
     6961 cagcgactaa tacttttgaa ataacaataa ttggcaaggg cgggcatgga gcagagcctc
     7021 ataattgtat agacccaatt gcagttggaa atgcagtata ttcatccatt caacagatag
     7081 tttcaagaaa aattgaccca gttgtacctg tagtagtgtc tgtttgttct tttaattctg
     7141 gtgtttctaa aaatataata ccagatgtat gcacacttca agggactatt agagcgataa
     7201 gcaaggaaca agtaattgaa gtaagtaaaa ttctagaaaa tatagtaaga aatgtatgta
     7261 gagcatacgg agcagattgc aaatttgaaa agagtacagg aggagatgct gttataaatg
     7321 acaaaaacat gatagagcta ggaagagaaa gtgcttgcaa aatacttgga gttgaaaatg
     7381 ttgaaataat tgattttcct gcaatgacag gtgaggattt tgctatttat atgaaagaaa
     7441 aacctggttt atttatgtat ataggtgtag gaaataaaga aaaaaatata aactacagat
     7501 tgcatagtaa caagtttaat atagatgaaa aatgtcttag tatagcatct tcattattct
     7561 cacaacttgc agtagattat ttatgtcaac tatagagtac attcataaaa atatatttag
     7621 cctattttta aatttaatgc tagtatatta attttgatgt agaacatatt atttattata
     7681 tttatttaaa aaggtggata acaatgataa aagtagaaaa tttacataaa agttttaaag
     7741 ggacagaagt tcttaaaggt ataaatttag agataaatca aagtgaagta gtagctatac
     7801 ttggaccatc tggaacaggt aaatctacgt tacttagatg tttaaattat ttagttgagc
     7861 ctacaaaagg aaagataatg attggtgatg taaaagtaga tgtagaaaaa gcaacaaaaa
     7921 aagatatagc caatttaaga aaacatacat ctatggtatt tcaaaattat aacttattta
     7981 aaaataaaac agcattagaa aatgtaatgg aggcattgat agtagtacat aaaaagagta
     8041 ataaagaagc tagagaaata tctttaaaat taatagataa agtaggtatg ttggatagga
     8101 aagattttta tccatcaaaa ttgtctgggg ggcagcaaca aaggataggt atagcaagag
     8161 cgatggcagt aaatccaaat gtaatattat ttgatgagcc aacatctgca cttgacccag
     8221 aacttgttgg agaagtttta agcgttataa aatcgcttgc gaaagaagga ataacaatgc
     8281 ttattgtaac tcacgaaata aattttgcaa aagaagttgc tgataaaatt atatttatgg
     8341 ataatggtgt aatagctgaa gaaggaactc ctgatgaaat atttaataat cctaaaaatg
     8401 aaagaactgc aaaattttta aatatcgtta ggaaagaaga agtatttagt taaaagtgta
     8461 taaattaagt attagaagat atgtaagata ctcccattaa atttataagt tagataataa
     8521 atttaatgga agtatctttt tattattaga tttattattt aatttaaaat tagaaatgta
     8581 actatttgaa aattcttttt aaaagtatat caaaaatatc aagtacatga aaaaataata
     8641 tttgacaaaa tatcatatat gtttacaaaa ttaacttgat ggaatgataa agcataggaa
     8701 ttacaatgag tatactaaaa ctttatatta aagtacaaat tattaaattt gaaaataatt
     8761 aagcaatatt atatatattt ttttatattg tttgttttat taaaattaat ctagaaaaaa
     8821 agttttaaaa gcagaatttt attaatattt atatatagat atgaactatt aataaaatat
     8881 taaagataca aaaaaactat agaaattgac atatattcca gtatttgcta aagtagctgt
     8941 tggggaaaat tacaaaaatt attaatgcgc attagataat ttactttaat ttttttagga
     9001 tttagggtaa tttataatat aaaacattag aaaggaaaat ataaatgagg gactttttaa
     9061 aaaattataa gtcatcaatt atacttttag catgtactat aataggggcg atagtaggat
     9121 tagtacttgg tccaaaagct tcaatactaa aaccatttgg agatttattc ataaatgctc
     9181 tattaatgat agtagtacca ttagtttttc ttagtgtttc ttcaggtgtt gctagtataa
     9241 aaaatatgga acgttttgga aaaataatga agagtacagc tatagtattt atgggaacaa
     9301 cacttgtaat tgcattttta ggtattacat ctgcattatt atttaatccg tctaaaggat
     9361 tagatgtatc aagtgtaaaa agtttaatgg tggctcaaga tgcagaaact ttagaatcaa
     9421 aaggaacgtt attagaccaa gtagtatcaa gtattacagt taaaaatttt ggagatttat
     9481 tttccagtag caatttacta caattagtta tatttgcagt tttagttgga acagcaatag
     9541 ctatgatggg agatagggga aatacaataa gaaagttttt atcagaagga acggaagcaa
     9601 tattaaaagt agtaagtata gtcatgcttt atgctcctat agggctaggc tgttatacag
     9661 ctacaataat tggggaactt ggaagcaaaa taattcaagg atatgtaagg gtgtttgtaa
     9721 tttattcact aacagcagcc atgtatttct tattatttta cagtctgtat gcttttttat
     9781 ctgcaggaaa acaagggttt agacaattct ggagaaatgc tataaaacca atagcaacgg
     9841 cactagctac ttcttcaagt tcagcatgta taccatcaaa tttagaagct agtaaaaata
     9901 taggagttcc tgatgatata tcagaaacag ttatacctct tggaataaat atacataaag
     9961 atgggtcagt tttagcagta ataataaaag tggcattttt atcaggtatt ttaggcagtg
    10021 gaatggcaaa tccagcaacg ataggtcaat tatttataac tgtatttgtt gttggagtat
    10081 ttatggctcc tgtagcaggt ggctgactta ttggtgagat gctcgtggtt agcatcttcg
    10141 gttttccagt ggaggcaatt ccattgttaa cagttataac tactataact gatattccta
    10201 atactatatt aaatacaact ggaaatacag tatcatcaat gttagtttca agattagtag
    10261 aaggaaaaga ttggcttata gataaaacag caattactac aaagaaaata agctaattgt
    10321 acacttaatt aataaagtta ataggtatct taattttaat aaattagata tctattaact
    10381 ttttaagtaa aaatataaat ttaagattca aatatgatat ttataatttg aattaactaa
    10441 tatagtatat attgaaataa atatgtttaa atatctagtt tatttttgaa agtaaaagat
    10501 ttcaaattta tttttattaa aagataacaa gccttcatct cgcatcttgc caagctctct
    10561 tgacatagaa cttctgtcaa cacataaaaa atcagccatt tcatttcttg aaaagggaat
    10621 tgtaaactgg tggctacctg tttgttctat ctgttttgaa aaatacataa gcaatttctc
    10681 gcgagttgtt ttacgagaaa gtaattctat tttattgtga agtaaaatgt ttttttcagc
    10741 tattaattgt agcatatttt caacaagcct attatgaaat acacatgcag atgaacaaat
    10801 accagttaca cttttaaact ttataaataa aacttcgcaa gaagatgttg tggttactgt
    10861 aacattactt ttatgtagtc tagtacatgc gaatacctct ccaaataaat ctccaggcaa
    10921 gagttcagct acaatattcc tattcccttc gatatcttcc tttattatat gagcacttcc
    10981 tttaagcata attccaatag aagtaacttc acttccaaca gagaatatta tactatcttt
    11041 tgggtaagtc ttatctacaa cacctaaaca ttccaacatt tcttcaagtt catcactttt
    11101 aattccttca aatagaggaa tttttttaag taggtctata tgcttttcta aaaatttttt
    11161 caaataatca cttccttgtt gcatatgcaa ccgataattt gttttcattg tactatacta
    11221 agtttataaa agcaagggga tataaaaatc ctaatacaag aaatttgaaa taaagaaata
    11281 taggtattaa aaataaatat ataagaaatc aatactttaa attaaaaaaa ttttatgagg
    11341 tgatataaat gatgagaaaa ataattaaaa ttgatgaggg aaagtgtaat ggttgtggac
    11401 tatgtgttga agcttgtcat gaagaagcta taggaatggt aaatggaaaa gcaaaacttt
    11461 taagagatga ctattgtgat gggctgggag attgtctgcc aacttgtcca acaaatgcga
    11521 tttcatttga gtatagagaa gcagcagaat atgatgaagc tgcagtaaaa gcaaatatgg
    11581 aagcaaagaa agcacaaaag aaaactttag catgtggatg tccaggttct cagtctaagt
    11641 caataaatag agaggtttca aatagtacat ctataagcaa tgatatagta gagataaaag
    11701 gttctcaact taatcaatgg ccagtacaaa taaaattagt accaactaat gcatcatatt
    11761 taaagaatgc aagtctttta atagcagcag actgtacagc gtatgcatat ggaaattttc
    11821 ataataaatt tatgaaaaat aaggttacat taatcggatg ccctaaactt gatgaagttg
    11881 actatgctga aaaactgaca gagattttaa aagaaaatga tattaaaaat atagtagtaa
    11941 cacgtatgga agttccttgc tgtggtggta tagtaaatgc tgttaagaca gctctacaaa
    12001 atagtggaaa aatgatacca tggcaaatag ttactatatc tgtagatgga aaaattgtag
    12061 atggagaaat ttaattaagt gaatcataga aaaatataat aaattttaat aaataaaaag
    12121 ggaggaataa aaaatggaaa aaatgttttg ttttcaatgt gaacaaacag caggaggtaa
    12181 aggttgtact ataaatggtg tttgtggtaa aaaggggggt acagctaact tgcaagacga
    12241 gcttacagga gtgttgattg gtctttcaag agcaactatt ggaaataaga atagaccaac
    12301 aagtgaaaca gataaaatta tgatagaggg gctattcact actataacga atgtaagttt
    12361 tgatgatgaa gctataaaaa gacaaattga aaaaactgag gtagaaaaaa gtaaacttgt
    12421 acctagatgt tcagattgtt caacaacttg taatagaaat gataactatg atatgaagga
    12481 tttatggaat gataatgagg atatacgttc attaaaatca ttaatcttat ttggattaag
    12541 aggcatggct gcctatgcat atcatgcaat ggtacttggt tatacagaca aagacgtaaa
    12601 tgaatttttc tatgaaggat taatagcagt tggaggagac ttgtctattg acgaactttt
    12661 aggtctagtt atgaaaactg gagaaataaa cttaaaatgt atggaattgc ttgatagagc
    12721 aaatactgaa acttatggaa caccagaacc gactcaggta tctatgaaaa tcgagaaagg
    12781 gccatttatt gtagttacag gacatgacct ttatgattta cacaaattat tagaacaaac
    12841 gaaagataag ggtataaata tatatactca tggtgagtta ttaccagcac atgcatatcc
    12901 aaaactaaaa gaatataaac atctaaaagg taattttggt acagcatggc aaaaccagca
    12961 aaaagaattt gataatattc ctgctccaat attatttaca acaaactgtt taatgcctgt
    13021 taaagatagt tatagagata gagtatttac tacagaagta gttgcttatc caggtatggt
    13081 tcatattgat gaagataaag atttttctag tgtaatagaa aaagctcttg aacttggagg
    13141 atatagagaa gatgttcata tgactggtat taatggagga gatacattaa ctactggttt
    13201 tgcaagaggt acagtttcat ctgtacaaga taaagtagta gatgctgtaa agagtggagc
    13261 tataagacac tttttatttg ttggaggttg tgatggtgca aaacctggaa gaaattatta
    13321 cactgaattt gtaaaacaag ctcctaaaga cactgttata ttgacacttg catgtggaaa
    13381 atatagattt aatgatttag accttgggga tataggtggc ttacctcgtt taatggatat
    13441 gggacaatgt aatgatgctt atagtgcaat taaagtggca gtttcattgg caaatgcttt
    13501 tgaatgtgga gtaaatgatt tgcctcttag catggtactg tcatggtatg agcagaaagc
    13561 tgtttgtata cttcttacac tacttcattt aggtatcaaa aatatctata tagggccttc
    13621 tttgccagca ttcttatcta agaatgtatt agatatattg gttgataaat ttgcattgac
    13681 acctatatct actcctgaag aagatatgaa gaagatttta ggataaataa atatatctat
    13741 acttaaagat atttatagtt aaaatatttt taagtatgcc acaattaaga taaggggtta
    13801 aacttaaaat ttgattaaaa aatcaatttt gaaacgaccc tttatttatt ttttgtaata
    13861 attgaaaaat aaacctgctt tcagtatatt cttttaagaa tttttgtatt aaatttataa
    13921 tacttagata tataatatct tatatatttt attttaagta ctaaaggttt gaatgtaact
    13981 taaatattaa aagaggaaca ttgtaatatg taacttgcat aaaatatata tactatagtg
    14041 aaattatttt aattaaaata taaggtgttt tatgtggggg tatatgtata tgaaaagttc
    14101 taattttaat atattggcat ttgatggtgg tggattaaaa ggggcattga gtatatccat
    14161 acttgagagg atagtaaaag agtatccaaa tctattaaac aatataaata tgtttggagg
    14221 tacatctaca gggagtctaa ttgcactagg acttgcgtat ggtgtaagcc ctaaagagat
    14281 aaaagaactt tactcaattg aaaattcaaa gtatattttt aataaaagtt atgcagaaat
    14341 actcagacca aagtatgaaa acaaaaactt aaaagaagtt ttattaagta tatttccaga
    14401 ggaactagaa ttaaaagatt taaataaatt agtaatgata ccaagttttt atataggaaa
    14461 tgaggaaaat gcatggaaac cagtatttta taacaatatg tcaaattctt ttacaaagac
    14521 tagcaaagtt gtagatgtag caatggcaag tagtgctgct ccggtatttt ttccaacata
    14581 taatcgtcat gttgatggag gaataatagc aactgaccca agtttagcgt gtataattca
    14641 tgccattgac agtggattta aacttaagaa tacaagactt ttttcaatag ggactggata
    14701 tgtatataac agtataaagg cagatactac tgaatgggga gctattgact ggataattaa
    14761 taaagaaccc gatttaccaa ttatatctat taccttagaa ggaaattctc aaatgagtca
    14821 gttattttct caaaaacttc ttggagataa ttactataga ttaaatccta agatggaaaa
    14881 agatgtagct atggatgatt gtgatgcatt agaatatcta atgtctttag gagaaaattg
    14941 tgatataaaa gatgcttttg gatggataaa gaaaaagagc ttttatagaa attagattca
    15001 atttgcaatt gtatttttac acatgatttc attgagtagg taaaaataat aaaatgcaga
    15061 ttattaagtt acttcttagg gaataaataa agtataattt atttaaggag tgatgaaaat
    15121 gataaaactt gctacttttg caggtggatg tttttggtgt atggtaaaac cttttgataa
    15181 gtatgatgga gttattaaag tagtttctgg atatacaggt ggtcatgttg aaaaccctac
    15241 atatcaagag gtatgttcag gaactactgg tcatttagaa gcaattcaaa taacatatga
    15301 tgatgatata ataagttatg atgaacttct aaatatcttc tggaaacaga ttaatcctac
    15361 agatgatggt ggacaatttg gtgatagggg aactcaatat aagactgcta tattttatca
    15421 tgatgaagaa caaaaaaata tagctttaga gtcaagagaa catctggaaa atagtaaaat
    15481 atttgatagt aaaatagtga ctgatataat tccagcaact aaattctacg aagcagaaga
    15541 aaatcatcag gattattata aaaaaagacc attaaactac aatatgtatt ataaagggtc
    15601 tggcagatat aattttgtaa aaagtcattg ggatggaaac aatataaata gggaagagtt
    15661 aaaaaagact ttaactccta tacaatttga agtcactcaa aatgatatga cagaagtacc
    15721 ttttgaaaat gaatattatg ataataacaa agaaggaatt tatgttgata ttgtaagtgg
    15781 agaagtgtta ttttcttcaa aagataaatt tgattctgga tgtgggtggc caagtttttc
    15841 aaagccagtt atagataaat ctatcattga gagaagtgat ttctcacaag gtatgtacag
    15901 agtcgaagta agaagtgcta aaggaaattc tcatttaggc catgtatttg atgatggtcc
    15961 aaaagaactt ggaggtttaa gatattgtat aaattctgct tctcttaaat ttataccgag
    16021 agaaaatatg gaagctttag gatatggaga atatttaaaa ctttttgagt aattaggaat
    16081 atttattata aacttatcta aaaggtgaaa atataagaaa atattttcac cttttgtttt
    16141 tttgtcaata atatgataaa ttattaattg taatcttatt tataccaata gattaagaat
    16201 ttaattttga aagagagaaa acaaatgaat ttaaaagact ttaatggaaa gagattaaaa
    16261 tcagctagaa tttttagagc aaagacgata gaacagttgt ctaaagaaac taaaataaat
    16321 aaaaaagatt taaaagcttt tgaggaaaat aagtatgtac caaatataga aaatacatta
    16381 aaattatcta atatattaaa ttttccaaaa gagtattttt ataaaaatga aaatataaat
    16441 atcgttgtag aggatagcca ctttaaccct caatctaaac tacctagagt agaagagatt
    16501 tcttatagag aaaaaataat tataatacat aaaatatatt catttatgga gaattatatt
    16561 aagtttccaa aagaaaactt gccaaataga aaagtaatgt cagatattaa tataaatgat
    16621 atagaatctc ttgcatataa gactagagag ttttgggatt taaatagtac tccaatagta
    16681 aatatggtaa gtttgttaga gtctaaaggg attataatat caggtatgaa tgtagataga
    16741 aaaggggcaa ctatctttac tcaaaaacag agaattagta aagaatctaa atatctaata
    16801 tctctgggta atgacaaaaa gtcagcatca attagaaatt atactttggc atgtgagctt
    16861 ggatatataa tatcaagtga attaagaata ccaagtaagc aattttcaga agatgagtat
    16921 gcttgtgcat ttttattgcc aaaagagagt tttttaaaag atttgactca tccagaagat
    16981 ttagattatt atgtagaact aaagaaaaaa tggattgtac ctatatctgc tatgattttt
    17041 agagcatata atctagaaaa gataaattac aaaaaataca attatcttat gaatgaaatg
    17101 gataaaaaag gctggttgat agaagaacca ctagacaaaa tgaaaggttc aagcccaacg
    17161 tatttaaaaa gagcagttga attattgata gaaaataaaa taatgagtgt aaatagtata
    17221 gtatcaagtt tagaggaatt tggaataaat ctttatccag aagacttaga attattgatg
    17281 ggattgaaaa aaggattgtt atctcaagag gtaaataaaa aaagtaaagt tataaaattt
    17341 gatggtaaaa aataggttta tattttagta ttaaaattaa aagcaggtat aaatgattta
    17401 aacattaact tagttaaaag tcttttcaat aagtcattta cctgctttta gtgtaagaaa
    17461 gaatattgaa tctaaagtgt ttttgaaagt gcaatatatt ctcttaaaac agagcaagat
    17521 ttattaaatt cgttttgctc atattcagtc atattgattt caataatttc ttcaatacca
    17581 tcttttccta taacacatgg aacacctgca aatacatttc tttcgttata ttgaccttct
    17641 agtaatgtag aaactggaag aacttttttc tcattgtgta gtatagcttt tacaatttct
    17701 actaaagcag tacctatacc aaattctgta caatctttac catttattat acttatccct
    17761 gtttttttat ttttttcaac tattgatggt aagtctaaat tgctataagt acttgggttg
    17821 tcttttatca cgtctaagat tggtttacca ccaattgaaa catgagacca aggaaccatt
    17881 tgagaatctc catgttcacc catagaataa gcttgaattg attgttgagc gattccagtt
    17941 tcttcagata aaatccttct aagtcttgtt gaatctaaag ctgttccagt tccaatgact
    18001 ttgtttttag gaaagccaga tttttcccaa atataatttg taactacatc aacaggatta
    18061 gatatgacta caaatatacc atcaaagcca gaatcaacta tgggttttac tatagatttt
    18121 atcattccaa tagttggtct tagtaaatct aatctagttg tgttttgtct acgtaaaggc
    18181 ccttctgaag agtctgcaac acttatcact actatgtcag aatctttaca gtcagaaaag
    18241 gttccttttt ctatatgtac tttatgtggt agatatgaaa ctgcatcagc taaatctaaa
    18301 gcttgagctt ttgatttaga ttcatctata tcaatcataa agagttcatc acaaactcct
    18361 tgagttatta aactaaatcc acaatgagaa ccaacatgcc ctgaacctac aatagatatt
    18421 tttcttggct ttattgccat tttaaatcac tccccctaaa ataacgatac attgaaaatt
    18481 atagatgtta tcaaaagctg tttttggata ttttaatatt ctattatttc agaaaattta
    18541 tttaatatga ttttatacta aaatttttaa aaaagcaatg ttaatatact ctctattaat
    18601 gaatgttaaa gtattatatg tatattaata attattaaaa tatgtaatgt cactgatagt
    18661 tagaatattt aagtgttaaa agatgtatat aaataataat gatatcagtt gataatgata
    18721 ttaaattgag gtatactgtt tctctaaatt aaaaaacaaa ggagtaaatg tgttatgaat
    18781 tatcatacaa aagaagagtt gatggaagta ctgagagtag catcttcaag gattattaat
    18841 tgtgaaaaag tacagaagaa attttctgag gagacatctc atcatacacg ttttaagaat
    18901 attatagaag caatgtatat ttcaaaatca ttaataatgg atgaaattag taaaagagat
    18961 tgaagcttat tttgcaattt aatatgtttt aatatacatt ttattatata agaaaataag
    19021 taagcatact tgttataaaa tattgaaata atataaaatt ataaatttgt taacactaat
    19081 atctatatgt taaaatatag tagaagatgt tagtaaataa taggatgagt tctattttaa
    19141 tacaattaaa ttaagcttag cttgaaattt gtatttaaaa agtaaagtag tctataatta
    19201 agaaaatgga gatagaatta taatggaaaa gttatattat acaaatcagt atataagaga
    19261 ttttacagca gaaataattg aaataaaaga agtagaaaat aagtatcatg ttttattaga
    19321 taagacaact ttttttcctg gtggaggagg tcagtttgga gacctgggaa aaatagagaa
    19381 tgatgatgta ataaatgtgt atgaagatgg aaaaaatata taccatgtat tagataaaaa
    19441 acctataaag atacataagg taaagtgtag tattgattgg gatagaagag aagatggaat
    19501 gcatcaacat tttggacaac atgtattatc tggatgtttt tttaaaactt ttaatgcaaa
    19561 tacgacaggt tttcatttag gaaatgagta tagtacagta gatatagaag gtaatttaga
    19621 agagaacaaa attagagaga tagagttgtt tgccaatgaa attattcgcc aaaatataca
    19681 agtagagaca ttacttccaa cgaaaaaaga actgaaaaag atttggttaa gacgtgattt
    19741 gccaaatact gatgaagaga taagagtgat aaaaataggt gatttagata cgaatgcatg
    19801 ttgtggagtg catccaaaat caactggtga attgagaatg ataaaaataa agaaatggga
    19861 aaaacataag tcaagtacaa gaatagagtt tctagcaggt aaaagggcag tggatgaagt
    19921 attgaagagg gatatatatt tgactaaaat atgtagatat ttaagctgta gtgaggaaga
    19981 tgctataaat ggtattgtaa atctaaatag taaagtagaa gaggctttaa ttaaaaaaag
    20041 aaggcttgaa gaagtagtat ctacatatca ggtcaaagaa atgattgaaa aagcaaataa
    20101 ggttggcaat atttcggtca ttaaaaaaat ttatgatgat gaagatttga aatatgtaaa
    20161 taagatagca aataaaattg cagaatatga aaatagtatt gcattattag ctgttaaatt
    20221 taatgataaa ataaatttag tttttgcatg ttctaaaaat ttaaaagata ttaatatggg
    20281 agttttatta aaggatgcaa taagccttat agatggcaaa ggtggtggaa gtaaagtatt
    20341 agctcaagga ggaggtaaga ataatggaaa tttagaggct acacttgatt atgcatttat
    20401 gaagatagaa aaaactctat aaatatatta tataaaaaat cttaatagat aaaatagata
    20461 tggaggaata agtatggagc aacaaaagga ctacatagag ttatatgaaa atgaagaatt
    20521 aatagagata agagaagcac gtatggatga tttggataca atagcaaaat ttaattataa
    20581 tttggctaaa gaaactgaag gaaaagaact tgatatggat gttttaacta aaggtgtaaa
    20641 agcattgtta ttagatgaga gaaaaggaaa atatcatgta tatacagtat ttgataaagt
    20701 tgttgcacag attatgtata catatgagtg gagtgattgg agaaatggaa atttcctttg
    20761 gattcagagt gtatatgtag ataaggaata tagaagaaaa ggtatcttta attatttatt
    20821 taattatata aaaaatatat gtgataaaga tgaaaatata gttggaatga gattatatgt
    20881 agaaaaagaa aacataaatg caaaagcaac atatgagtct ttaaatatgc atgagtgtga
    20941 ttataatatg tatgaatacg aagtaataca ttcgtaatat aaatttgtaa tactgttata
    21001 ctgatgttat aaagtattga ttatattgac gattatatga aataaactgg atattataat
    21061 tagaattttt agggggtata aaaatgggcg ttttaaaagg aatgttttat gtatttttat
    21121 ttttagattt agtgtcaata ttctgtttct ttttcaataa aggaaaaata gcatctaata
    21181 aaattgtgtt taatgcaata ggagtactta catttgtact ttgttttatg ctttttagtt
    21241 attatcctaa taataatctt attggaaaat ttattgcatc tctatttttt atatttggag
    21301 ttgcaggagt tatgttgaaa gaaaaaaatt ttttatatgc tagacttctt ttaactgtag
    21361 ttatagtttt ttctacacta agattgttcg ttattcaata aaatgtattt gtatgaaaat
    21421 ttattaaagt ctacacattt aagtgtaggc ttttttgctt tcttatttaa gaattaagga
    21481 aattttaagg aaattttaaa atcgtcttaa atatttattg atatacttaa aatattaata
    21541 gcgaaaggag acttatcagt gatagaaagt aaaaagtcag aaaaattgtt actgtcaatt
    21601 atatatataa tatttttggt atatatttta atgattataa gaataatttt atttagagat
    21661 gtaccaattt acgctatttt caagggaacg tttaggactg taaatttaat tccattttat
    21721 acaatatatc aatttatagt agatagtaat cttgacttta tgaaagctac tgtaaatatt
    21781 atagaaaata taggtatatt tattcctatg ggaatttttt tacctatagt atgtaaaaat
    21841 ctaaataaaa aaactataat tatagcaatt atatttgtta gcctagcatt tgaattaaca
    21901 caatatattt ttgctcttgg aagtagtgat atagatgatg ttattttaaa ttcattaggt
    21961 ggaataattg gaattaatat ttacataaac atgaataaat tatttcctaa tgatattaaa
    22021 agatttaagg ctataatagc tactagttta gttttaggag ttatttctaa aaattatcat
    22081 aacttactaa cttttaaatt tagacctgat agaaaaatat caaaaatatt aattgaagaa
    22141 aatagggaaa taattaaaga tataaataaa gatacagtag atatagttgg gacatttgag
    22201 agctttaaaa aaggaataat aactattaaa gcaggttcta ataacaaagt aaagagacca
    22261 gagaatttaa ttgattctga tggaaatata agaatttatt taaatgaaaa tacaaaatta
    22321 gtatcttata taattaccaa agaatcaaaa atggatatag ttaaatatga ggaatttgat
    22381 gtgaagaatt tagatttatt aaggagatat gatactatta atgtttggat tgataaagaa
    22441 aatcagccaa aggataaaca tggtattatg gctagtaaat tattaattgg attgtatgaa
    22501 taaaatatta aacaagaata aaagaataac aaatataaaa aacgaaaaaa ctatttctat
    22561 aattattttt acgttgtgca taaaataaga acattagtga aggagtagag ataaattatg
    22621 gagataataa aatatatctt gtactttttt atatattcat ttttaggatg gacagtagaa
    22681 agtataggat gttctatagc aagcaaaaga ataatcaaca gaggtttttt aaatggtcca
    22741 atatgccctg tttatggttt tggagcggta attgtgatat cactattggg aagatttaat
    22801 aatgtagtaa tagtatttct attaggaatg attttaacta cgatactaga atattttaca
    22861 ggatttattt tagaaacttt atttcatgct aaatggtggg attattctga cagaaaattc
    22921 aatataaagg gtagagtatg tttaaaaaat gcaatatact ttggtgtaat gtctgtttta
    22981 ataataagat ttatacatcc atttataaaa tattttgtaa gtataattcc atatagaata
    23041 ttaatttcaa tggctataat tacaacactt tggactatac ttgatttgat tgttactatt
    23101 ataacactta aaaaattaga tataaagtta aacttactag acgatataat tacagacctt
    23161 aatgatataa atgtgaaatt ggataaattt gatagaggag aaatacaagc tttatttaaa
    23221 acaataaata acgacgaatt agaagttaga gaaaaaataa acaaaataaa tagtaagttg
    23281 gaccgtatag agtctaatat tattttacaa aaaagagtta taaaagcttt tccacatata
    23341 aaacataaaa aacaacaaga gcaactagaa cattttaaaa aaattattaa tgagaaaagg
    23401 taattataca atttaatgaa gacgaataga ataatggtat ttataagatg attttcagag
    23461 gactctataa aaatagaata gagtccttta ttttttgaaa aataatgttt atttgataaa
    23521 aataaaatat attgtttcta aataacaaat attttgaaaa ttataaaaac atatattgac
    23581 aatttgtgtc aaaaatacta acattaagta tataaagaat tttatatgag aatatcttta
    23641 taaatcgcaa taattttaaa acataaattt atttaaagag gggatgattt gccaatgagc
    23701 gagataacta gtcaaatgat aagtacagaa gaaaaaaaat atgttgctaa aactcaaaag
    23761 ataccttatt atccagtagc atttaaatca ggtgatggtg caatgctata tgattatgaa
    23821 ggtaatgaat atgtagattt tttagcaagt gcaggctctg caaatgtagg tcatggtaat
    23881 aaggaaatct cacaagcagt taaagaacaa atggatgata taacacaata tacacttgca
    23941 tatttccata gtgatcctcc tgtaaaatta gctgagaagc ttgtggaaat agcccctgga
    24001 gataatgata aaaaagtact atacagtgca actggttctg cttgtataga tgctgctata
    24061 aaattagcaa gagggtatac tggaagaaca aagataatat ctatgtgtga atcttatcat
    24121 ggaagtactt atggagctat atctatatct gctttaagta caaatatgag aagaaaaatg
    24181 ggtccattgt taccagaagt ttatcacttc cattatcctg ataaaaatag aacagctaaa
    24241 gaatgtttag atgagataga atatgctttt gcacactatc taccagcaga agaggtagct
    24301 gcaatattta tagagccaat tgcaggagat gcaggaataa tagtgcctcc agtagagtgg
    24361 gtacaaggtt taagtaaaat atgtaaagaa aatggaatat tacttgtaag tgatgaaata
    24421 caacaaggta tgggaagaac aggtaagtgg tttggtatag aaaattttgg tgttgaagca
    24481 gaccttatag ttcttggaaa atctgttgga ggtggattac ctttaggagc agttgttgga
    24541 agaacagaaa taatgcaaag tcttgatgca ccagcacatt tatttacttt agctggaaat
    24601 acaacagtgt gtgtcgctgc tttaaaatct atagagataa ttgaaaaaga aaacttactt
    24661 caaaagagta tagaaatggg agattatatt aaagcaggat ttgaaaaact aaaagaaaaa
    24721 tacgatataa ttggagaaat aagaggaata gggttatcta taggagttga tatagttaaa
    24781 ggaaaaggtt ctaatgaaaa acatccagat gctacagcta agatatgtta tagatgtata
    24841 caaactggat taataatgat attcttagga caatctactt taagagtaca accacctcta
    24901 gtaataacta aggagcaagt agataaagca atgagcatca tagattctgc aatagatgat
    24961 tatttaaatg gtagaattgg tgatgaagta tatgaagtaa ctcaaggttg gtaaaataaa
    25021 tattaaatga aaataagagt tatctcaatt ttagaaagta atttctgaaa tgagataact
    25081 cttttaagtt acccacaaat aagaaaattg tttgattcat taaagactat atttcggatg
    25141 tcgtttttgt gagtatcaga gacagtatta cgagaataat tacctttatt cgtactatct
    25201 gttaatttag ttataattaa gatagctaaa agaataagaa ttactgtgta taaagcaata
    25261 acatatggtt ttcttttata tttgtatttg ttattgaaaa aagaatggcc ataattattt
    25321 ttatttactt tagatgtatt tgtattcttt ttcttgttac ctttcttttt atcatccttt
    25381 tttctatttt tagggtaagg aatgactttg tgtgtattat caagtttgat atttttattt
    25441 ttttgaatat tgttttccag gctagccttt ttttctccaa attgaatagt tttattggta
    25501 ttgttgttat ctttcaatgt taatctccct cccttaaact ttccctttag ataatattac
    25561 tactaaccta tggaatatac aataaataat atataagtaa taaaatttta taggtataaa
    25621 tctctttctc cacgctctaa ggcagtcata ttgttagata ctatgtttct tatatcttct
    25681 ctttctatct tacctatttc ttctgcgata agttttttac ccataatttt aagttcttca
    25741 tctccataat cgattaaaaa ttcatttaat gtagtaagag catttggcgt acatacatta
    25801 tggatttgtc gacttttagc taagctcatg aatctatcgc cagttctacc tttacgataa
    25861 caagctgtac aataactagg tatatatcca tcagtaatca gttctttaag cacctcaaca
    25921 gggcttctat ggtctccaac ttcgaattgt tctgtattgt caccatcttc atatgcttta
    25981 tatcctccaa cacctgttag agaacctgca ctaatttgtg atacaccata ttttagtaac
    26041 tcatttctca tttcagcagt ttctctagtg gacattatga ttccagtaaa aggaacagcc
    26101 aatctagtta tagctactat ttttttgaac atatcgtcag aaactaagtg aggaaaatct
    26161 tctaagctca taccttcagc ttttttcaat ctagggaaag atatagtatg gaaacctaca
    26221 ccaaattttt cctctaagtg ttcgttgtgc atcataagtc ctagaacttc aaatttaggg
    26281 tcagataaac caaataaaac tcctgcacca acatcatcaa caccagcttc catagctcta
    26341 tcaaaagctg ttaaatggta ataatagtca ttttttatag attgaccatg catttttata
    26401 aatgttggtt tgtgataagt ttcttggaat aatatataag ttcctattcc tttttctttt
    26461 agtaatttat actcatctac acttgtagct gctatgttaa cgtttaccct tcttatattt
    26521 ccgttttcat tatatgttga ataaattgca tctaagcaat ctaagatgta atttatatca
    26581 caatttttag ggtcttcacc agcttctaga gcaagtcttt tatgacccat tttttctaat
    26641 attttaacct cttcctttat ctcttccatg gtaagttttt ttcttttaaa tttgttgcat
    26701 ttactaaaac cgcaataaac acattcattt acacagtagt ttgatacata aagaggggca
    26761 aataaaacca ctctattacc atatatttca ttttttattt gcccagctat actaaataat
    26821 ctatctagtt gttttttatc ttctacttca agaagtgtag ctatatcttt ataactaagt
    26881 ttttcccttc tatcagcctt atcaagtacc ttttcaatat catcagaagt tgaatttttt
    26941 gcatcttcta ataaagaatt aataagttca tggtttatga acatttacaa acgcctccat
    27001 tcaatattat caccgcgaga atagtcaact tcaagtccta atgacttgat gttttcttct
    27061 aaactttggt gatattcaca agcttcttga ccagtaaagg ctttgttatc gtaaagagaa
    27121 tattgttttc taaattcttg aggagaaagg tttggcataa ttacattgca accagctaaa
    27181 agacctgcat ttctaccact agggtttata gatgccaagg ctgttgtagc gggtaataaa
    27241 acttttggaa gtagaagtct tgtaattgaa agcataagta atgtcttctc taaatctcca
    27301 tgtttataat ccttaaaaat tgtatcatgg tgtggaataa aaggtcctat tccaaccata
    27361 tgaggattta actcttttag gtataataaa tcacgaacaa ggtcttcgtt gttctgaaat
    27421 ggtgattcaa ccataaatcc agcacctacc tgataaccaa tttctttaag gttttttagg
    27481 cattcttttc tagttctaag ctcaatgttt ggcggatgta attttttata atgactgtct
    27541 gtagcagttt catgtcttaa aagatatcta tctgcaccac ataaaaagta ttttttatac
    27601 gaatcataac tcttttctcc tagtgacaga gttatggcac aatcctcata tttatttttt
    27661 atacttgaaa caatttcaca tattttatca tcagtaaaat atgcatcttc accaccttgc
    27721 aaaacgaatg ttctgtatcc tattttataa cctatatcac aacattcaag tatttcatca
    27781 ggtgaaagtc tgtatcttat gatattttta ttagaagatt gtattccaca atagtagcaa
    27841 ttatttttac aatagtttgt aagctctata agtcctctca agtagactct atttccataa
    27901 tgtttatttc tcatgtcgct agcttgttta taaagatagt ttcttaaatt ttgttcgaag
    27961 ttatattcct cattgtcgat attttctatt aaatatagta gttcatcaaa acttaatgaa
    28021 ttaatgctgt aaagtttatc tataaagtat ttaatcttat ttttagtcat attcaaatat
    28081 gtaattatta agtatagtta aatttttaat aattgaaaag ttcaagtgat ctttccaaaa
    28141 taccttttac atatgctatt aagataccat agtttacaat aggtacattg aaagattttg
    28201 ccttttctat tctagataac attccagctc tattcatcat acaagctcca cagtgaacta
    28261 caagggcata tttatttata tcttcagtga aggatactcc agagctaaat tcaaaagtaa
    28321 tatttttgcc agttttcttt ctaatcatat taggaatttt tactgttcca atatcatcag
    28381 tttgtctatg atgggtacat ccttcggcca tcaagatttt atcaccatct tttaaatttt
    28441 ctaaagcata agcgccatta atcaattctt taaggtctcc cttttgtcta gcaaacaata
    28501 tagaaaaaga tgtaagagga atatcttttg gtgtatcttt atttacttgt ggaaatactt
    28561 gagagtcagt aataacaagt tttggttttt tgcctaaatt agatagagtt tcttttaaac
    28621 tatcttcttt tgtaactata gaaattgcac cattatccaa aatatctctt ataacttgtt
    28681 gttgaggaag tataagtcta ccttttggag ctgctttatc tattggaaca actaaaacaa
    28741 ctaaatcatt tggttcaatt aaatctgata ccaatttgaa ctcagtgcta tccttaggca
    28801 aaacttttat tatttcattt tttaaatttt caattccaat tttatctgtt gatgagacag
    28861 aaacaactgg acatttaact ttatttttag ttaagtttaa aatttctgat tgattcttaa
    28921 tagtatcaat tttgttgaga attagaatat gagggatatt cttatcatta aacttttcaa
    28981 ttagtgacaa atcttcttgt gatataccaa tctggcaatc cactactagt aaagctatat
    29041 ctgtcttttc taaaacatct agtgatttac ctattctaag ttcaccaagt tcaccaacat
    29101 catcaagacc agcagtatct ataagaacac aaggtcctat aggaaggatt tccattggtc
    29161 taaatactgg gtctgtagta gttccagcaa tatctgagac tattgcagca ctttgatttg
    29221 ttatagcatt tattatgcta gatttacctg catttctttt accaaagaga cctatatgta
    29281 ctcttaccga ttgtggagta gaatttagac tcatttgtac tcaccacctt aaacttcttt
    29341 ttttgatata ctagttttta cagatacatg aggtatgttg cccaatttac cagtcaaact
    29401 attaatagta tccatttcgc caacaactgc tatacatacg attgagacac cttcttcttc
    29461 gcaaggaatg cccattcttc ctttaataat acctttaaaa cctgatacaa cctcattgaa
    29521 tttaaattga cattcttttg gctcttccaa aatagcactt ataactgcaa cctttttcat
    29581 aaatatcctc ctaactcaga aaatatgtct taaacaaatc caaaatcaaa aaacttttct
    29641 ttgtaaagaa aagtttctac aaaagaaaag ttattaatta cacaagtata atgtgctata
    29701 ttaaactatt tccttacaga ttagataact cttttctggt agggttagct tgtaaaaatt
    29761 taatttaaca acaagtaact gaagaaaatt tttatacaat ttatataaat tataataaaa
    29821 attaactaaa gaaaattgaa gttacttata taatagtagt aaattgaaat taagtctata
    29881 gaaaaaccaa tttttgtata aaaataaaaa ttaaagttaa ttatttgtta agaattgact
    29941 ttggtaaaat atataattaa ttattcttta agcatataat ttataagtaa ttttagtgta
    30001 ttttcaatag cttctatatg tgttctttca taatggtgac tattgtttgt tccaggacca
    30061 acacatgcta tttgaacatc ttctccccaa cgaatagctt ctgaagcatc tgaaccatag
    30121 aaagtaaata catcgacagc gtagtctaaa ttattgtctt ctgcaacatc gacaagcttg
    30181 tttcttaaat taaaatcata taatgataaa ttatcttttg caactatagt tacaccatgt
    30241 tcactagatg tttgacttgg tccagtaggt gctatatcta ttgctacaaa ttcttttgtt
    30301 ttttcaggta aacatttaga aacaccatgt ccaatttctt cataattact tatataaaag
    30361 ttagtagtat gcttaggtgt taaattgttt tctttaaaat atctacatat ttcaagaacc
    30421 attgctacag ctgatttatt atctatatat ctagatttta taaaaccaga ttctgtagcc
    30481 tcaaatctat ggtctaggca tacaaaatcc ccaacactta ttcctaaatc taatacatct
    30541 tgctttgtaa atactttttc atcaagtcta ataatcattg tttcttcatt tctttcagtg
    30601 gcagcttttg tttgaccata tatatgagta gaagcatact taaatacaac acttcctctg
    30661 atttttttac cttttctagt tataacagtg cagttttctc cctctatagc tgcccaacat
    30721 ccaccaccaa ctttatggta tttaagagta ccatcagatg atatttcttt tactatagct
    30781 ccaagtgtat ccatatgtgc agatattgtt atttgatttg aatcatcttc accaggaaga
    30841 gtagctataa gtgcaccttt ttttgtaaga atagtgtcaa gacctaaatt ttcaaaatct
    30901 tttttgcttt ctaaaactgc attttcagta tatccagctg ggcttggaat gtccaaatat
    30961 tttttcatta aatttatagt attagttaaa tttaaattca tattgtttcc tcctaaataa
    31021 atatatttat acaaattata acataaatac aaatgttctg aaaactaaaa ttaaaagaat
    31081 agaatctaaa catatttaaa aaaaaagtat ataaaataaa tttgatttat attatataga
    31141 tttaaagtaa aaa
//
LOCUS       DACTZW010000041        30801 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.041, whole genome shotgun sequence.
ACCESSION   DACTZW010000041 DACTZW010000000
VERSION     DACTZW010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30801
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.041"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(50..925)
                     /gene="hslO"
                     /locus_tag="JAM15_10400"
     CDS             complement(50..925)
                     /gene="hslO"
                     /locus_tag="JAM15_10400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HAT6798663.1"
                     /translation="MRDYVLRATSGNGQVRAFVATTRNTVEEARRLHETTKVATAALG
                     RTLTATSIMGLMMKNDSDKLTVIIKGGGPIGTIIATSDSKGMVKGYVGNPQVEVEDYP
                     NGKLNVAAAVGTEGVVKVIKDLGLREPYNGTYPLVSGEIAEDFTYYFAVSEQTPSVVA
                     LGVLTKEDEVEFAGGFIVQLMPDAEEETIAKLEENVAKLPSITNMLKEGKSPEDILNI
                     VLDGLEPKILDTCEVGFMCECSKERVKTALVAIGKKSLAQIIEEDKKAEVGCQFCNKK
                     YMYSEEELLEILKEM"
     gene            complement(1210..1956)
                     /locus_tag="JAM15_10405"
     CDS             complement(1210..1956)
                     /locus_tag="JAM15_10405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAT6798664.1"
                     /translation="MSQYSDFAFVYDELMNEVDYNGWVKYIEDIIDSEGVKVKNILEL
                     ACGTGNLTIPLTKKNYDIAGIDISDEMLSVAREKAEKEGVELVLLQQDISELDFEISD
                     LDCVLCACDGFNYITYDDDLENVFSKTYELLKKDGIFIFDISSFYKLANILGNNMYGE
                     NREDIAYMWQNYFDEEENLIEMELTFFIKDECGKFERFEEIHQQRAYTEDEIVDMLEK
                     SGFKDIKYYGDFTFDKPSEESQRIFFVCKK"
     gene            complement(1943..2188)
                     /locus_tag="JAM15_10410"
     CDS             complement(1943..2188)
                     /locus_tag="JAM15_10410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small, acid-soluble spore protein, alpha/beta
                     type"
                     /protein_id="HAT6798665.1"
                     /translation="MKEKVQREKKITNGKNTKILTNDDIMKYEIASELGLMDKVGERG
                     WAGLTAKEAGRIGGMLTSRKKRLKKIVEEQNKKDESI"
     gene            complement(2318..3436)
                     /locus_tag="JAM15_10415"
     CDS             complement(2318..3436)
                     /locus_tag="JAM15_10415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HAT6798666.1"
                     /translation="MREASYLQEQLYKHRKSLNPIAEIGRKEYKTSKYIRDYLDKLGI
                     EYEVYLETGIVGVIEGKRPKKDIAFRADIDGLHSEEGVKHLCGHDGHATILLGLIEYL
                     NDNKEDLNDNIVFIFQPAEEGPGGAKALIDEGVLRKYNIDEIYGLHIYPELPEGYVGT
                     REGYFMAQIGDIDIEIVSKSGHGAMPQNGIDGIVIASNFVSSLQTIVSRNISPIDNAV
                     LTIGRIEGGARRNIIAENIKMEGTMRCFSPEVYEKMKLRVRELARGFELAYNCKVNIN
                     IIDDYIAVKNDKDLYQEFVEAIGSDTVVELEPLMISEDFSYYQKEVPGLFFMLGSRNE
                     EKGFVNGLHNINFNFDEKICVNALNVYSKLLKYKEAID"
     gene            complement(3642..4835)
                     /locus_tag="JAM15_10420"
     CDS             complement(3642..4835)
                     /locus_tag="JAM15_10420"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007790779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HAT6798667.1"
                     /translation="MDTLKELFKIGSGPSSSHTMGPQRAAERFKNENPDAESFRAILY
                     GSLAATGKGHLTDYIIEKTIAPKKVEIVWEEDIIKDFHPNGMKFEALDKDKNVTAEWT
                     VYSVGGGTIAEEGQRNSKSNSIYHLDTMDEIVKWCKENNKTLVDFVLECEPKDIKDYI
                     KTIKDAMRKSIDDGLSTDEIIPGKLLLKRRASTFYNAYKKDKSFSTLVYAYALAASEQ
                     NASGNIIVTAPTCGSAGVIPGIFFAMQDFYNYDDEKIIEALLVAGIIGNIIKTNASIS
                     GAEVGCQGEVGAACSMAAAAVAYLKGGTIDHIEYAAEIALEHHLGMTCDPVYGYVQIP
                     CIERNAMAAQRAYDAANYALLTDGSHSVSLDQVVETMKETGIDMMDKYKETAKGGLAK
                     HFFSC"
     gene            5158..6039
                     /locus_tag="JAM15_10425"
     CDS             5158..6039
                     /locus_tag="JAM15_10425"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HAT6798668.1"
                     /translation="MLFKGSAVALVTPFTEDNNVNFEKLGELIEYHIENGTDALVVCG
                     TTGEATTMSESEIFAVIKYTVEKVNKRIPVIAGTGSNNTMLSVHMSQEAEKLGVDGLL
                     IITPYYNKTNEKGLKLHFETIANSVKLPIILYNVPGRTKVNIKPSVMAELAKIDNIVA
                     VKEASGDLAQVAEIAKLVPKDFAIYSGNDDTILPLLSLGGSGVISVLANICPKETHDL
                     VTKFFEGDIEGSKKLQLDMDALIAALFIEVNPVPVKTAMNILGFNVGDLRLPLAEMEE
                     TNLNVLKQELTNFGFKF"
     gene            6464..7465
                     /locus_tag="JAM15_10430"
     CDS             6464..7465
                     /locus_tag="JAM15_10430"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HAT6798669.1"
                     /translation="MKKVNVAIVGATGMVGRTFLKVLEERNFPIENLFLFSSSKSAGS
                     KVMFCGKEYIVEELKETSFTDRGIQIALFSAGGSISEKYAPIAASNGILVVDNSSQWR
                     MNPDVPLVVPEVNPEAIKNHKGIIANPNCSTIQAMVPLKALDDKYKIKRVVYSTYQAV
                     SGSGVKGVEDLEKGMNGNPTGFYPHQISYNCLPHIDSFTENGYTKEEMKMVNETMKIL
                     DNYDLKITATTVRVPVKNGHSESINVEFNNPFELDDLVKTLEEAPGVVVVDNPSKNEY
                     PTAVEFDDRDEVFVGRIRRDFSVDNGVNLWVVADNIRKGAATNAIQIAEMALSYDLV"
     gene            7582..8469
                     /locus_tag="JAM15_10435"
     CDS             7582..8469
                     /locus_tag="JAM15_10435"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HAT6798670.1"
                     /translation="MIFKGSAVALVTPFTKDNKVDFDKLGELVEYQIANGTDAIVSCG
                     TTGEANTMTDEEQLATIKYVVEKVNKRVPVIAGSGSNDTMHSVNLSQEAEKLGVDALL
                     IITPYYNKANKAGLKRHFETIANSVKLPIILYNVPGRTCVNISPSLIVELAKIDNIVA
                     VKEASGDLGQVAEIASLVPDDFAIYSGNDDTILPLLSLGGQGVISVLANVCPQETHDL
                     VAKFFEGDIEGSRKLQLGMDALIAALFIEVNPIPVKTAMNLLGFNVGDLRLPLAEMDP
                     ANLEVLKKELVNFGLKVNA"
     gene            8536..9285
                     /locus_tag="JAM15_10440"
     CDS             8536..9285
                     /locus_tag="JAM15_10440"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HAT6798671.1"
                     /translation="MLKVIATGYDGKMGKILADTIREDNELELVCVAARGLDSYEGDL
                     KIYEDMSTIVEEADVVIDFSHHSNLDNILSYVLKTKTPLVIATTGYNDNEMNKIREAA
                     KVIPVFQSYNMSLGVNVLVKLVKDAAKLLEGFDIEIIEKHHNRKVDAPSGTAVMIANA
                     IKEVLPNVENNYGRYGRSAKRQPNEVGIHAIRGGNIVGEHDALFAGDNEVLTISHQAQ
                     SRGIFASGSIAAAKYLVKQKPGFYNMDSMLG"
     gene            9509..10225
                     /gene="dapD"
                     /locus_tag="JAM15_10445"
     CDS             9509..10225
                     /gene="dapD"
                     /locus_tag="JAM15_10445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HAT6798672.1"
                     /translation="MVNLNDAYEIARYIKEVKKKTPVKVYVNTNSLHFQSTDKFKVFG
                     SNGSYIFVGDYEDIMEVLDKHGNDITDTHVEYDRRNSAIPLKNTLNEHARIEPGAIIR
                     DMVTIEKNAVVMMGAVINIGAVIGEGSMVDMNAVIGARGTLGKNVHLGAGAVVAGVLE
                     PPSATPVIVEDDVLIGANAVILEGVRIGKGAVVAAGAVVTTDVEAGAVVAGSPAKVIK
                     MKDEKTADKTKLMEDLRNLD"
     gene            complement(10496..11485)
                     /locus_tag="JAM15_10450"
     CDS             complement(10496..11485)
                     /locus_tag="JAM15_10450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HAT6798673.1"
                     /translation="MLKEEKTYQEKDAKVFNGVAALIMIVLFLVVSIGIMVFGIVKLD
                     SGFTGIGSLMLILGLVFIVVDFILFFGLKMINPKEAIVLVLFGNYYGTIKKEGYYWVN
                     PFCSAINPAVSRINVSKSSSDEKVDISTNSRGKKVSLKTMTLNNEKQKVNDLLGNPII
                     IGVVVIWKVIDATKAVFNVDNYNTFLSIQCDSTIRNVSRLYPYDVSEDGDEKSLRGSS
                     QEIADRLKDELQSRVDIAGIEVCEVRITHLSYAPEIAAAMLQRQQAEAIIAARKKIVE
                     GAVSMVEMALTNLSENNVVTLDEERKAAMVSNLLVVLCGNKDAQPVVNSSSIY"
     gene            11926..12681
                     /locus_tag="JAM15_10455"
     CDS             11926..12681
                     /locus_tag="JAM15_10455"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HAT6798674.1"
                     /translation="MLKVIINGYNGTMGRVLAECVKKDNELELVCGVARSADEKGHHS
                     DTKLYKTMTDVTEKTDVIIDFSHHETLEPILSYALKNNTPVVLATTGYDENDLNKIEE
                     ASKNIPILLSSNTSLGVNILIKLVKDASKMLEGFDIEIIEKHHNRKEDAPSGTATMIA
                     NAIREVLPESENTHGRYGRDCKRKPNEIGIHSIRGGNIISDHDVIFAGDNEVLTLSHH
                     SQSDEVFANGSIVAAKFLIGKQSGLYKMSDILG"
     gene            complement(13035..14711)
                     /gene="bclA2"
                     /locus_tag="JAM15_10460"
     CDS             complement(13035..14711)
                     /gene="bclA2"
                     /locus_tag="JAM15_10460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA2"
                     /protein_id="HAT6798675.1"
                     /translation="MSDISGPSLYQDVGPTGPTGATGPTGPTGPRGATGATGANGITG
                     PTGNTGATGANGITGPTGNMGATGANGTTGSTGPTGNTGATGANGITGPTGATGATGA
                     NGITGPTGNKGATGANGITGATGPTGNTGATGANGITGPTGNTGATGANGATGLTGAT
                     GATGANGITGPTGATGATGANGVTGATGPTGNTGATGPTGSIGATGANGVTGATGPIG
                     ATGPTGADGEVGPTGAVGATGPDGLVGPTGPTGPTGATGANGLVGPTGPTGATGANGL
                     VGPTGATGATGVAGAIGPTGAVGATGPTGADGAVGPTGATGATGANGATGPTGAVGAT
                     GANGVAGPIGLTGPTGANGVAGATGATGATGANGATGPTGAVGATGANGVAGPIGPTG
                     PTGANGTTGATGATGATGANGATGPTGATGATGVLAANNAQFTVSSSSLGNNTLVTFN
                     SSFINGTNITFPTSSTINLAVGGIYNVSFGIRAILSLAGFMSITTNFNGVAQNNFIAK
                     AVNTLTSSDVSVSLSFLVDARAAAVTLSFTFGSGTTGTSPAGYVSVYRIQ"
     gene            complement(15089..15628)
                     /gene="hpt"
                     /locus_tag="JAM15_10465"
     CDS             complement(15089..15628)
                     /gene="hpt"
                     /locus_tag="JAM15_10465"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HAT6798676.1"
                     /translation="MDIETKKWEVLYSEEKIKDKLRELGAIIEKDYKDKNLMVVSLLK
                     GSFIFCADLVRNINLPLRVNFMTTSSYGNNEESTGKVKVVSDVTTDIAGYDVLVVDDI
                     TDSALTMDFVLKHLKAKNPASLKCCVLLDKPSRRKVDLVPDYCGFEIEDKFVVGYGFD
                     FGDYYRNVPYIFNVTDEDR"
     gene            complement(15956..17263)
                     /locus_tag="JAM15_10470"
     CDS             complement(15956..17263)
                     /locus_tag="JAM15_10470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine dehydratase subunit alpha family protein"
                     /protein_id="HAT6798677.1"
                     /translation="MRDIRKELVEMLKAEVKPAVGCTEPVALALACAKAKELLGEEIV
                     ENRMLVSPSIYKNGMCVGIPGTERLGLKIAAALGIVGGHSENGLSVLETLTKEEVKIA
                     EDYMDNTPLSITPADTREKVFIEVVLKGKNHIAKVRIRTKHDNFTFLEKDGEVLLDNE
                     PKVSASNDAAEKAESLMDTVTIQELIKNVEEIDFKDIEFLLDGVKMNEEMAEYGLKQK
                     TGIGVGYGIKKSIEEGLLGNDVINYAMMLTAGASDARMAGVKMPVMSSNGSGNHGLTA
                     ILPIVAYNKKFPQPDEKLAKALAISHLVTGYIKNYTGRLSAVCGCGVAASTGATAGIS
                     WLMNGTEKQIEGAIENMIADLSGMICDGAKAGCALKLSSAASAAIQSAIIAKQDCFVP
                     PLNGIVGSSVEQSIQNLGRVSDKGMSITDEIILNVMNDMNKVD"
     gene            complement(17688..19463)
                     /locus_tag="JAM15_10475"
     CDS             complement(17688..19463)
                     /locus_tag="JAM15_10475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAT6798678.1"
                     /translation="MMVMIGLEYIKSDIQNIAEAIVSVLNIDVTIVNKELFRIAGTGV
                     YIDKIGEKVDKYTAFKKSLTEQITILIDDPKSSDVCRECYKSGACVEFAEVCCPIICD
                     GDSHGVIGLIAFTKEQAQIIENNKSGLINFLGKMADLISNKLKAQIKTYELELEKKKL
                     ETLLNNMDKAVVSIDVDGKIDKYNSKFKELFNIKDSITGKNIFVELDFIKKPSINNFK
                     KDKSCSFFYKRYGYDSKGIYNINKIVLKNELKGYVIDFIDKRDAIKNYNKMNKDYRIK
                     LENIIGESVAIRNSKKEALIASKSTSTVLITGESGTGKELFARAIHNHSNRVDNPFIA
                     VNCAAIPDNLLESELFGYEEGAFTGAKKGGKLGMFEVAHKGSIFLDEIGDMSLHLQSK
                     LLRVLQEKELNKIGSKSNVSIDVRIIAATNKDLEKMVQNGTFREDLYYRLNVIPIKLP
                     SLRERKEDIPLIIKHMVKEYSKKLDKNVIDIDSRVVDAMMEYKWPGNIRELQNIIEYS
                     VNMSSSSIITMNVIPQKIKNTSVEELEVKSDRIIPLDELEKIEIIKALNKYKDYKKDK
                     ELTAKALGISRATLYRKIEKYNIIS"
     gene            complement(19675..20244)
                     /locus_tag="JAM15_10480"
     CDS             complement(19675..20244)
                     /locus_tag="JAM15_10480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAT6798679.1"
                     /translation="MKSILCQINKQPVKAKYTSDELECFLDTIEYNVGDKILLVGHIG
                     NLGKRLRGLGTSVTILENSNYEDVCYSLVYNENCNVVKGKLEFLPFDDNQFNKIIIVD
                     QFNVITDCEKASSEIQRVLKGNGEVILEDLNLKNLKVKLNYLKHKFCGSVAKIHYPHE
                     VFNIFSRLNFDGMIKESNKLKYIYVGKRR"
     gene            complement(20428..21063)
                     /locus_tag="JAM15_10485"
     CDS             complement(20428..21063)
                     /locus_tag="JAM15_10485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAT6798680.1"
                     /translation="MIAVKDENNVVNLRGELDNKLEFSHEIFGEKFYNMKIKINRLSD
                     SFDILPMTVSERLLQDIDLDKQNLVNVVGQLRSYNKTLNNKNRLVLTVFVREIKSIDE
                     ENKDPNSIFLDGYVCKEPVYRKTPLGREITDLLVAINRPYNKSDYIPSIVWGRNAKFA
                     KNLKVGDRIQLWGRVQSREYEKKIDENNVVKKMAYEVSISKIKKLDENNNE"
     gene            complement(21731..22612)
                     /locus_tag="JAM15_10490"
     CDS             complement(21731..22612)
                     /locus_tag="JAM15_10490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HAT6798681.1"
                     /translation="MVAILKALYVVFAAIFAVVFGKDVAKANKEGKLEEQSTPKVAVT
                     GFITDFFDTLGIGSFAPTIAMSKALKLNIPDKKMPGTLNVAHTIPVVTEAFIFTSIIP
                     VDGVTLVSMVVAAAVGSYIGAGIIAKMDERKIQLVMGVTLALTAILMLLGHPWINVLP
                     GGGNELGLTGVKLVIGVIGNFILGALMTAGIGLYAPGMAMVYFLGMSAKVAFPIVMGS
                     CALLMPVASMKFIKEDAYTKKASVIIAICGLIGVFVAAYIVKTLPMDILKALVIVVIA
                     YTSATMIMAANKNKKTA"
     gene            complement(22732..23739)
                     /locus_tag="JAM15_10495"
     CDS             complement(22732..23739)
                     /locus_tag="JAM15_10495"
                     /EC_number="5.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline racemase"
                     /protein_id="HAT6798682.1"
                     /translation="MKFSRSIQAIDSHTAGEATRIVVGGIPNIKGNSMPEKKEYLEEN
                     LDYLRTAIMLEPRGHNDMFGSVMTQPCCPDADFGIIFMDGGGYLNMCGHGTIGAMTAA
                     IETGVVPAVEPVTHVVMEAPAGIIRGDVTVVDGKAKEVSFLNVPAFLYKEGVEVDLPG
                     VGTVKFDISFGGSFFAIIHASQLGLKIEPQNAGKLTELAMKLRDIINEKIEIQHPTLA
                     HIKTVDLVEIYDEPTHPEATYKNVVIFGQGQVDRSPCGTGTSAKLATLHAKGELKVGE
                     KFVYESILGTLFKGEIVEETKVADFNAVVPKITGSAYITGFNHFVIDEEDPLKHGFIL
                     K"
     gene            complement(23798..24241)
                     /locus_tag="JAM15_10500"
     CDS             complement(23798..24241)
                     /locus_tag="JAM15_10500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
                     /protein_id="HAT6798683.1"
                     /translation="MSFVGISTSMKNTSLHIFRDPLLDLIDNDSDIDLLGVVVVGTSE
                     HNEWKTFLATRLGRWIESLRPDGVIITLDMAGNQHIDFTNAIAEFVKSDIPAVGLTIM
                     GADGLVITNPYLDKATIIDYKKTTGYIETEVVGDNHMDEVDVKKA"
     gene            complement(24259..24726)
                     /locus_tag="JAM15_10505"
     CDS             complement(24259..24726)
                     /locus_tag="JAM15_10505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
                     /protein_id="HAT6798684.1"
                     /translation="MGIGPSTKETSLHHFRDPLLDIVESDKDVDLLGVIVVGTPDGNE
                     NKTFVGQRTAAWLEAMRVDGAIVSSDGWGNSHVDYANTFEEIGKRDIPVVGVTFNGTQ
                     AKFVVSNQYMDTIVDMNKSKEGIETEVVGENNTNEIDAKKALAFLKLKMRKHG"
     gene            complement(24741..25499)
                     /gene="prdD"
                     /locus_tag="JAM15_10510"
     CDS             complement(24741..25499)
                     /gene="prdD"
                     /locus_tag="JAM15_10510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase cluster protein PrdD"
                     /protein_id="HAT6798685.1"
                     /translation="MEEKIMRRLVIKPFHMNEVNFGSKTSIKKDVLTIDLSSIDEIKE
                     REELITDIKVDIIKPGDYDREINTIMDIIPISTKVLGRLGEGITHTLTGVYVMLTGAD
                     EDGNQMHEFGSSEGILKDQMVFGRYGTPSVEDYIIHVDVTLKGGLPFERTLPLAAFRA
                     CDDFIQEIRASLKMEDGRNATQVREYFDKIRPNAKKVVIVKQIAGQGAMYDNQLFSKE
                     PSGFEGGTSIIDMGNVPMIISPNEYRDGALRAMT"
     gene            complement(25579..26304)
                     /gene="prdB"
                     /locus_tag="JAM15_10515"
     CDS             complement(25579..26304)
                     /gene="prdB"
                     /locus_tag="JAM15_10515"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(25852..25854),aa:Sec)
                     /transl_table=11
                     /product="D-proline reductase (dithiol) protein PrdB"
                     /protein_id="HAT6798686.1"
                     /translation="MSLTTVQGLQSEIFVPITPPPVWTPVTKELKDMTIALATAAGVH
                     LKSDKRFNLAGDTTFRAIPNTATVDEMMVSHGGYDNGDVNKDINCMFPIDRLHELAAE
                     GFIKGVAPMHYAFMGGGGNQHVFTEETGPAIAAKLKEEGVDGVVMTAGUGTCHRTAVI
                     VQRAIEEAGIPTIIIAALPPVVRQNGTPRAVAPLVPMGANAGEPHNIEMQTHILRDTL
                     EQLVAIPSAGKIVPLPYEYKAHV"
     gene            complement(26342..26626)
                     /locus_tag="JAM15_10520"
     CDS             complement(26342..26626)
                     /locus_tag="JAM15_10520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798687.1"
                     /translation="MDRLKYISSETFYEGIIVDIKGGGVTIDLKGRLGQFKIPNRMLI
                     TDYELKIGQEVGFMLSYPEVLSPEPNQEYVENISREKEKQAEMQSKQEEK"
     gene            complement(26707..28587)
                     /gene="prdA"
                     /locus_tag="JAM15_10525"
     CDS             complement(26707..28587)
                     /gene="prdA"
                     /locus_tag="JAM15_10525"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-proline reductase (dithiol) proprotein PrdA"
                     /protein_id="HAT6798688.1"
                     /translation="MSITLETAQAHANDPAVCCCRFEAGTIIAPENLEDPAIFADLED
                     SGLLTIPENGLTIGQVLGAKLKETLDALSPMTTDNVEGYKAGEAKEEVVEETVEEAAP
                     VSEAAVVPVSTGVAGETVKIHIGEGKNISLEIPLSVAGQAGVAAPVANVAAPVASAAA
                     EVAPKVEEKKLLRSLTKKHFKIDKVEFADETKIEGTTLYIRNAEEICKEANETQELVV
                     DMKLEIITPDKYETYSEAVLDIQPIATKEEGELGSGITRVIDGAVMVLTGTDEDGVQI
                     GEFGSSEGELNTTIMWGRPGAADKGEIFIKGQVTIKAGTNMERPGPLAAHRAFDYVTQ
                     EIREALKKVDNSLVVDEEVIEQYRREGKKKVVVIKEIMGQGAMHDNLILPVEPVGTLG
                     AQPNVDLGNMPVVLSPLEVLDGGIHALTCIGPASKEMSRHYWREPLVIRAMEDEEIDL
                     VGVVFVGSPQVNAEKFYVSKRLGMLVEAMEVDGAVVTTEGFGNNHIDFASHIEQIGMR
                     GIPVVGVSFSAVQGALVVGNKYMTHMVDNNKSKQGIENEILSNNTLAPEDAVRIMAML
                     KNAIEGVEVKAPERKWNPNVKLNNIEAIEKVTGEKIVLEENEQSLPMSKKRREIYEKD
                     EN"
     gene            complement(29016..30776)
                     /gene="prdR"
                     /locus_tag="JAM15_10530"
     CDS             complement(29016..30776)
                     /gene="prdR"
                     /locus_tag="JAM15_10530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator
                     PrdR"
                     /protein_id="HAT6798689.1"
                     /translation="MFSIPEVKKVEEVMDTKFTTIDEDTRIEDAIKEMIKSNTKTLMV
                     IDSSDQLKGIISMTDIHNLYEMHKKYEGQPVKLIMKKDVIYVNEGLTLDECRDIMILK
                     NIGILPVLRDNKIIGVLKQEHIRDYLYMHLEDYGLTLKYIIGQIKEGICAINNEGVVI
                     LWNKFMEERYDIKSEDIVGRPMNEFLENTISEKVLNSKVGMSDLYFTDKKENMYALVH
                     ANPIFYKEEFIGVVCTEVDVTEAKILALELEKVNDTLKYLKNEVKNLSKGSFDKILGK
                     SYKLEKSKAIAKQVARTNSSIFIWGESGTGKEVFARAIHDYSERKGQFIPVNCSAIPN
                     ELFESEFFGYESGAFTGASKKGRIGIFELAKDGTVFLDEIADLPLSMQAKLLRVLQEK
                     EIRRVGGDTTIKINPRIISATNKDLSKMVKAEKFREDLYYRLNVVEIKIPPLRERKED
                     IGLLVHSFLEEICKQNNKPVLTISKDVIDIFQNYRWKGNIRELKNTIENIVVLSQNSK
                     IDVDDVPSYMMDSTNNSTEEEEYPLDLTKATQKIEIKNITKALKMSNGNKAKAAKILN
                     IPRTTLYYKIDQYKIDVSKI"
BASE COUNT         9512 a         5591 c         3896 g        11802 t
ORIGIN      
        1 tactatatca ctataacatt acttatatca atacaactat ttttatagtc tacatttcct
       61 ttaaaatttc aagcaactct tcttcactat acatatactt cttattacag aactggcaac
      121 caacttctgc ttttttatct tcttctatta tttgagccaa tgatttttta ccaattgcaa
      181 ccaaagcagt ttttactctt tcttttgaac attcacacat aaacccaact tcacaggtat
      241 caagtatttt aggttccaaa ccatccaaaa caatatttaa tatatcctct ggtgattttc
      301 cttcttttaa catgttagtt atagaaggta atttagctac attttcctct aacttagcaa
      361 tagtctcttc ttctgcatct ggcattaatt gaactataaa tcctccagca aactctactt
      421 catcttcttt tgtaagaaca cctaaagcta ctactgatgg agtctgctct gatacagcaa
      481 aataataagt aaagtcttct gcaatttctc cacttaccaa tggataagtc ccattatatg
      541 gttctctaag acctaagtct tttataactt ttacaacacc ttctgtacct actgctgctg
      601 ctacatttaa ctttccattt ggatagtctt caacctctac ttgtggattt cctacatatc
      661 cttttaccat tcccttagaa tctgatgtgg cgataatagt tccaattgga cctccacctt
      721 ttattattac agtcaattta tcactatcat ttttcatcat taatcccatt atagatgtgg
      781 ctgttaatgt tcttccaagt gctgctgttg ctacttttgt agtttcatgt aatcttctag
      841 cttcttctac tgtatttcta gtagttgcga caaatgctct aacttgacca tttcctgatg
      901 tcgctcttag tacataatct ctcattaata ttcctccatg tcccgttaat tgtcttattt
      961 ttattatatt actaccttaa ttttaatcta taagtactta tctatcttaa ccttgggcaa
     1021 aacccatttt attttaattt tactaagcaa tagttattat attttaattt ttatctatag
     1081 aactttataa ttattagaaa ataaaagtca taaagtatca tcactttact tttaatctat
     1141 aaaactgcat tttctatatt tttatatcat ggttattttt aataattatc ttatatagtc
     1201 aaaaatatct tattttttac atacaaagaa gattctttga ctttcttcac tgggtttgtc
     1261 aaatgtaaaa tccccataat attttatatc cttaaatcca gatttttcaa gcatatcaac
     1321 tatctcatct tcagtatatg ctctttgttg gtgtatctct tcaaatcttt caaactttcc
     1381 acattcatct ttaataaaga atgtaagttc catttcaatt agattctctt cttcatcaaa
     1441 gtaattttgc cacatatacg ctatatcttc tctattttct ccatacatgt tatttcccaa
     1501 tatgttggct aatttataaa aagaacttat atcaaatatg aatattccat ctttctttaa
     1561 taattcatat gtctttgaaa atacattttc caaatcatca tcataagtta tataattaaa
     1621 tccatcacaa gcacaaagca cacagtccaa atcagatatt tcaaaatcaa gctctgatat
     1681 atcttgttga agtaaaacta attctactcc ttctttttct gccttttctc ttgctacact
     1741 aagcatctca tcagatatat ctataccagc tatatcgtaa ttttttttag tcaatggaat
     1801 tgtaagatta cccgtgccac atgccaattc caatatattt tttactttta caccttcact
     1861 atctattata tcttctatat atttaaccca accattataa tcaacttcat tcataagttc
     1921 atcatataca aacgcaaaat cactatattg actcatcctt tttattctgc tcctccacaa
     1981 tctttttaag cctctttttg cgtgatgtaa gcatacctcc aattcttcct gcttccttag
     2041 ctgtaagtcc tgcccatcca cgttcaccaa ctttatccat aagacctagt tctgaggcta
     2101 tctcatattt cattatatca tcatttgtca atattttagt attcttgcca ttagttatct
     2161 tcttttctct ttgtactttt tctttcaaaa aaatcacccc ttcttatttg tatttttgtc
     2221 aattaaaata aatttataca aatatataag gggtatttat taatacattt ttttaaattt
     2281 aggtatttat gctttttaat ctttataatt tatcttccta atctattgct tctttgtatt
     2341 ttaataattt tgaataaaca ttcaatgcat ttacacatat cttttcatca aaattaaagt
     2401 ttatattatg aagaccattt acaaatcctt tttcttcgtt tcttgaaccc aacataaaaa
     2461 ataatcctgg aacttctttt tgataataag aaaaatcttc tgatatcata agtggctcta
     2521 actctacaac agtatcactt ccaatagcct ctacaaactc ttgatacaaa tccttgtcat
     2581 ttttaacagc aatataatca tctataatat ttatattaac cttacagtta taagccaatt
     2641 caaaccctct agcaagttct ctaactctaa gcttcatttt ctcatacact tctgggctga
     2701 aacatctcat agtaccttcc atctttatat tttcagctat tatatttctt ctagctcccc
     2761 cttcaattct accaatagtc aacactgcat tgtctattgg gcttatattt ctagacacta
     2821 tagtttgaag tgagcttaca aagtttgaag ctatcactat accatcaata ccattttgtg
     2881 gcatagcccc atgtccactt ttagacacta tttctatgtc gatatctcct atttgagcca
     2941 taaaatagcc ttctcttgta cctacataac cttctggtaa ctctggatat atatgaagcc
     3001 catatatttc atcaatattg tattttctaa gcactccttc atctattaaa gcttttgctc
     3061 ccccaggacc ttcttctgct ggttggaata taaatactat attatcattt aagtcttctt
     3121 tattatcatt taaatactca attaatccaa gtaatatagt agcatgtcca tcatgaccac
     3181 ataaatgttt taccccttct tcactatgaa gaccatctat gtcagctcta aaagcaatat
     3241 cttttttagg tcttttacct tctattacac ctactatacc tgtttctaaa taaacttcat
     3301 actcaattcc taatttatca agataatctc ttatatattt tgaagtctta tactcttttc
     3361 tcccaatctc tgcaatagga tttaatgact tcctatgttt ataaagttgt tcttgtaaat
     3421 atgatgcctc tctcatgtaa tctcctccaa tttctaattt attaaaaaat atttctatat
     3481 ttctttataa ttaaaatatt atatagcatg ttatactaat taaaaataaa aagctaaatt
     3541 gaatataaaa atattttgca ttattaaata attcaccatt aataataatt cccctgtttc
     3601 ataaatcaaa acagaggaat tattattgga aaattttatt tttagcaaga gaagaaatgt
     3661 ttagcaagtc cacccttagc tgtttctttg tacttatcca tcatatctat accagtttct
     3721 ttcattgttt caacaacttg gtctaaggag acagaatgtg agccatcagt taataatgca
     3781 taattagctg catcataagc tctttgagct gccattgcat ttctttctat acatggaatt
     3841 tgaacatatc catatacagg gtcacaagtc attcctaaat gatgttcaag tgctatttct
     3901 gccgcatatt caatatggtc tatagttcca ccttttaagt atgctactgc tgctgctgcc
     3961 atagaacaag ctgctccaac ttcaccttga caccctacct ctgctccaga tattgaagca
     4021 ttagttttta ttatattacc tattattcca gctacaagta gtgcttcaat tattttttcg
     4081 tcatcataat tatagaaatc ctgcattgca aagaatattc ctggtattac tccagcagaa
     4141 ccacaagttg gtgctgtaac tattatatta ccagaagcgt tttgctctga agctgctagt
     4201 gcatatgcat atacaagtgt tgagaagctc ttatcttttt tatatgcatt ataaaatgta
     4261 cttgctcttc tttttaataa taacttgcct ggtattattt catctgtact tagtccatca
     4321 tcaatagatt ttctcatagc atcttttata gtttttatat aatcttttat gtcttttggt
     4381 tcacattcca acacaaaatc taccaaagtc ttattatttt ctttgcacca ttttactatc
     4441 tcatccatag tatctaagtg atatatacta ttgcttttac tgtttctttg accttcttct
     4501 gctatagtcc ctccacctac agaatataca gtccattcag ctgttacatt tttatcttta
     4561 tctaaagctt caaacttcat cccatttggg tgaaaatctt ttataatatc ttcttcccaa
     4621 acaatttcga cttttttagg tgctatagtt ttttcaatta tatagtcagt taagtgacct
     4681 ttccctgtag ctgccaaact accatataat attgctctaa aactttctgc atctgggttt
     4741 tcattcttaa atctctctgc tgctctttgt ggtcccatag tatgagaact tgaaggtcca
     4801 cttcctattt taaaaagttc ctttaaagta tccatattat tcctcctaaa tttacggtat
     4861 tattgcttat tgttagattt tacgcacata tttattataa cctaaatata ttaattatta
     4921 gttattaaat tctcataaaa tttatttttt atttccattt tggtatattt tattaaatta
     4981 atatgcatat tttgagaata aaacatttat ttaaaatttt tctaatatta atataatata
     5041 aatatcttat ttaaacagtt aagatattaa ctatacctat taaaattaat taatttgtac
     5101 tataattatt attgtactta aaaaattaaa tttagataaa aaaggagatt tgattatatg
     5161 ttatttaaag gttctgctgt tgctttagtt accccattta cagaggataa taatgtcaac
     5221 tttgaaaaat taggtgaatt aatcgaatat cacattgaga atggcacaga tgcactagtt
     5281 gtttgtggaa caacaggtga ggcgactact atgagtgaat ctgaaatttt tgctgtaata
     5341 aaatatacag ttgaaaaagt taataagaga atacctgtta tagcaggtac tggttcaaac
     5401 aatactatgt tgtctgttca tatgagtcaa gaagctgaaa aattaggggt ggatggtctt
     5461 ttaataataa ctccttacta taataagact aatgagaaag gtcttaaact tcactttgaa
     5521 acaatagcaa atagcgttaa gttgccaatt attttataca acgtaccagg aagaactaaa
     5581 gtgaatataa agccatctgt tatggccgaa cttgctaaaa tagataatat agttgctgtg
     5641 aaggaagcaa gtggagactt agctcaagtt gcagaaatag ctaaattagt acctaaagac
     5701 tttgctatat actccggtaa tgatgatact atactaccac tattatcatt aggtggaagt
     5761 ggtgttatct ctgtacttgc taacatatgt cctaaagaaa cacatgattt agtaactaaa
     5821 ttctttgaag gtgatattga aggctcaaaa aaattacaac ttgatatgga tgctttaatt
     5881 gctgctttat ttatagaagt aaatccagtt cctgttaaaa ctgccatgaa cattttaggt
     5941 tttaatgttg gtgatttaag acttcctcta gctgaaatgg aagaaactaa tcttaatgtg
     6001 ttaaaacaag aattgacaaa ttttggattt aagttttagc aatatttata taaataagtt
     6061 gattttttct taaatatgta ttattattag aataatcaaa ttttaatatc ctattaacct
     6121 agggtagagg tagctgtaac taagagtatc caatagtagc tggcaggtgt taatgattgg
     6181 aaaaaggatt tacagccgaa gaaaatattt cttgcaataa tattttctgg gattgcacat
     6241 aacatgtgta atactgtcac ttatttttgt aggtgatgag ctacagggtt tactttgagt
     6301 gataaattag acgtacaaag tatacctttg tacgtttttt gtatataatt aaagttgtta
     6361 atataatatt aaagtttttg gatatataaa aatattaaca tatcttactt gtataactaa
     6421 aataaaataa tgttttaata atttaaaatt ggggtgaatt tatatgaaaa aagtaaatgt
     6481 agcaatagtt ggtgctactg gaatggtagg tagaacattt ttaaaagtat tagaagaaag
     6541 aaattttcca atagaaaatc tatttttatt ctcttcttct aaatcagctg gttctaaagt
     6601 aatgttttgt ggtaaagaat atatagtaga agaattaaag gaaacttcat ttactgatag
     6661 aggcatacaa atagcattat tctctgctgg tggaagtatt agtgaaaagt atgctccaat
     6721 agctgcttca aatggaatct tagtagtaga taactctagt caatggagaa tgaatccaga
     6781 tgtgccttta gtagttcctg aggttaatcc agaagccata aaaaatcata agggtataat
     6841 agctaatcct aactgctcta ctatacaagc tatggttccc cttaaagctc ttgatgataa
     6901 atacaaaatt aagagagttg tttactctac ttaccaagct gtatctggtt ctggtgttaa
     6961 aggtgttgaa gatttagaga aaggaatgaa cggtaatcct actggattct accctcatca
     7021 aatctcttac aactgtcttc ctcatataga ttcattcact gaaaatggat acactaaaga
     7081 agaaatgaaa atggtaaatg aaactatgaa aatacttgat aactacgatt taaaaataac
     7141 tgcaactact gtaagagttc cagtaaaaaa tggtcatagt gaatctataa atgttgagtt
     7201 taacaatcca tttgagttag atgatttagt aaaaacactt gaagaagctc caggtgttgt
     7261 agtagttgat aatccttcta aaaacgaata tccaactgct gtagaatttg atgatagaga
     7321 tgaagtattt gttggaagaa taagaagaga ttttagtgtt gataatggtg taaatctttg
     7381 ggttgttgct gacaatataa gaaaaggtgc tgcaactaac gcaattcaaa tagctgaaat
     7441 ggctttatca tacgatttag tataatatac aaacttgtat aaatatataa ttttgtaaaa
     7501 tattaatagt aactcaaaaa caagcattag aagtaactgt aatataaaac acaaaaataa
     7561 aaaagagggg attgatttta tatgatattt aaaggttctg ctgttgctct agttacacca
     7621 tttacaaagg ataacaaagt tgattttgac aaattaggtg aattagttga ataccaaata
     7681 gctaatggta ctgatgctat agtatcttgt ggtactactg gtgaagctaa tactatgact
     7741 gatgaagaac aacttgctac tattaagtat gttgttgaaa aagttaataa aagagttcct
     7801 gttatagctg gaagtggttc taatgatact atgcactcag ttaacttaag tcaagaagct
     7861 gaaaaattag gagtagatgc tctattaata ataacacctt attacaataa agctaataaa
     7921 gctggactta agcgtcattt tgaaacaata gctaacagtg ttaaacttcc aattatactt
     7981 tacaatgtcc ctggaagaac ttgtgtaaat ataagtccta gccttatagt tgaacttgct
     8041 aaaattgata acatagttgc tgtaaaagaa gctagtggag acctaggaca ggttgcagaa
     8101 atagctagtt tagttccaga tgactttgct atctactctg gtaatgatga tactatactt
     8161 cctttattat ctttaggagg tcaaggagtt atatcagtac ttgctaatgt ttgccctcaa
     8221 gaaactcacg atttggtagc taaattcttt gaaggcgata ttgaaggttc tagaaaatta
     8281 caacttggta tggatgctct aatcgcagct ttatttatag aagtaaatcc tataccagtt
     8341 aagactgcaa tgaatttatt gggattcaat gttggagatt taagattacc tctagcagaa
     8401 atggacccag caaatttaga agtgttaaag aaagaattag ttaactttgg actaaaagtt
     8461 aatgcatagt aaagattaat gcatggtaaa aagtaagttt ggtcaaaagt tagcccttaa
     8521 tcataggagg aaattatgtt aaaagttata gcaactggtt atgatggaaa aatgggtaag
     8581 attttagccg atactataag agaagataat gaattagaat tggtttgtgt tgcagctaga
     8641 ggtctggata gctatgaagg cgaccttaaa atttatgaag atatgagtac tatagttgag
     8701 gaagctgatg tagttataga tttttctcat cactctaatt tagataatat cttatcttac
     8761 gttttaaaga ctaaaacacc tttagtaatt gctactactg gatataatga taacgaaatg
     8821 aacaaaatac gtgaagcggc taaagttatt cctgtattcc aatcatataa tatgtctctt
     8881 ggtgtaaatg tattagtaaa attggttaaa gatgcagcta aattactaga aggatttgat
     8941 atagaaataa tagaaaaaca tcacaacaga aaagtagatg ccccaagtgg cacagctgtt
     9001 atgattgcta atgctataaa agaggttttg ccaaacgttg aaaataatta tggtagatat
     9061 ggtcgtagtg caaaaagaca accaaatgaa gttggtattc atgctataag aggtggaaat
     9121 attgttggcg aacatgatgc tctatttgct ggagacaatg aggttcttac aataagccat
     9181 caagctcaat ctcgtggtat ctttgcaagt ggttctatag ctgctgccaa atacttagtt
     9241 aagcaaaaac caggatttta taatatggac agcatgttgg gataatagta taaatataat
     9301 aatacacaat ataaattaaa catatgcaat atagatataa taatacgcaa tacaaatcaa
     9361 acatatataa taaatttatt taatactatg tctatacaat aaaaactaac taaaataaaa
     9421 tataaataat aagaagtaag tatatactaa aattgacaaa taagtatata ataaaagaaa
     9481 tataatgaaa tacaaggaga attaacaaat ggtaaattta aacgatgctt atgaaatagc
     9541 aaggtatata aaagaagtta aaaagaaaac acctgttaag gtatatgtaa atactaactc
     9601 tttacacttc caatcaactg ataaatttaa ggtatttgga agtaatggtt cttatatatt
     9661 tgtaggtgac tatgaggata taatggaagt attagataaa catgggaatg atataacaga
     9721 tactcatgta gaatatgata gaagaaattc tgctattcct ctaaaaaata ctttaaatga
     9781 acatgcaaga attgagccag gtgcaataat aagagacatg gttactatag aaaaaaatgc
     9841 tgttgtaatg atgggagctg ttataaatat aggagctgtt attggtgaag gttctatggt
     9901 agatatgaat gctgttattg gagctagagg aactcttggt aaaaatgttc acttaggtgc
     9961 tggtgctgtt gttgctggtg ttttagagcc accttctgct actcctgtta tagttgaaga
    10021 tgatgtttta ataggagcta atgcagttat tcttgaaggt gttagaatcg gtaaaggtgc
    10081 tgttgttgca gctggtgctg ttgtaactac tgatgtagaa gctggtgccg ttgttgctgg
    10141 ttctcctgct aaagttataa aaatgaaaga tgaaaaaacg gctgacaaaa ctaagcttat
    10201 ggaagacctt agaaatttag actaattaaa tagtactata ttattaatta gaaagattaa
    10261 ttaaacaata atatactaat ttaaaaaatt aattaaaaag gtgtctctgt atgaatttaa
    10321 ttcatcagag gcaccctctt ttttataata tttttatctt ttatttataa tcattttatt
    10381 tttttacaat tctcttattc attcttatat catttttatt tcttgatgac aagtattttt
    10441 atttccttca atttttcaat atatcaatgt aataaactat taaacttttt ataatttaat
    10501 aaatagaact gctgtttact actggttgtg catctttatt gccacaaagc acaactaaca
    10561 gattacttac catagctgct ttacgttctt cgtccaaagt cacaacatta ttttcactta
    10621 aattagtcaa tgccatctct accatactta cagccccctc aacaatcttt ttacgtgctg
    10681 ctattatagc ctctgcttgt tgacgttgta acattgctgc tgcaatctct ggtgcataag
    10741 aaagatgagt aattctcact tcacacactt caattcctgc aatgtcaacc cttgattgta
    10801 attcatcttt taatctatct gctatttcct gactactacc acgaagagat ttttcatctc
    10861 catcttcaga tacatcatat ggataaagtc ttgaaacatt acgaatagta gaatcacact
    10921 gaatagataa gaatgtatta taattatcca cattaaatac tgcctttgtt gcatctataa
    10981 ccttccaaat tacaaccact cctattataa ttggatttcc caataaatca ttgactttct
    11041 gcttttcatt attaagagtc attgttttta aagatacttt tttgcccctt gaattagttg
    11101 atatatctac cttttcatca gatgaagatt tcgatacatt aattcttgat actgctgggt
    11161 ttattgctga acaaaatgga ttcacccaat agtacccttc tttttttata gttccataat
    11221 agttaccaaa caaaactaga actatagctt ctttaggatt aatcattttt agcccaaaaa
    11281 ataggataaa atctactact ataaatacaa gtcccaaaat taacataagt gaacctattc
    11341 cagtaaatcc actatcaagc tttactatcc caaaaaccat gatacctatt gaaactacta
    11401 aaaataatac aatcattatc aaagctgcca ctccattgaa tacttttgcg tctttctctt
    11461 gataagtttt ttcttctttt aacatatcta tcactcccat ctcagtatat taagttaaga
    11521 tatttctaat ttaataataa cacttttaac aattaaattg ttgaatttaa aattaatact
    11581 atatgtttat atatttttta tacatcttta tgcatacatg tatttagtta ttttaatgta
    11641 ttaatattga tttccaaata aatcatatga tatatgaata tggtatctca aaattaactt
    11701 tttagttcat ggggcactct ttttgatatg aagtcaaata tatttttatc atttatacaa
    11761 tgaaaaagaa gtttatctat attttgaaaa atccacttaa atttttttaa tgtaagataa
    11821 attgtaagct tattatcact aatattattt tatataaata atattagtga taaaataaac
    11881 ttatagaaat ataacaaatt tttattaatt tcataggagg aatttatgtt gaaagttata
    11941 attaatggct ataatggaac aatgggaaga gttttagcag aatgtgtaaa aaaagataat
    12001 gaattagagt tggtttgtgg tgtagctagg tctgctgatg aaaaaggtca tcatagtgat
    12061 acaaagcttt acaaaacaat gactgatgta actgaaaaaa ctgatgtcat aatagacttt
    12121 tcacatcatg agactttaga gccaatattg tcatatgctc taaaaaataa tacacctgta
    12181 gtattagcta ctactggata tgatgaaaat gacttaaata aaatagaaga agcatcaaaa
    12241 aacattccta tattattatc atcaaataca tctcttggag tgaatatatt aataaaatta
    12301 gttaaggatg cttcaaagat gttagaaggt tttgatattg aaatcataga aaaacatcac
    12361 aatagaaaag aagacgcccc tagtggaact gctactatga tagctaatgc aattagagaa
    12421 gtcttgcctg aaagtgaaaa tacacatggt agatatggta gagattgtaa aagaaaacca
    12481 aatgaaattg gaatacactc tataagaggt ggcaatataa tcagcgacca tgatgtcata
    12541 tttgcaggtg ataatgaagt tcttacatta agccatcatt ctcaatctga tgaagtattt
    12601 gcaaacggtt ctatagttgc agctaaattt ttaattggta agcaatctgg actttataaa
    12661 atgtcagata tactaggata agttttgtac ataataaatc tcaatctatt taggtattca
    12721 tattcatcaa tttgaatatc taattgattg agatttctat tctaaaagtt tataaatttt
    12781 atgcttacct tttaaatata atcatttttc ttaaagatta tcttatttat tggtatatgg
    12841 aattatattg tttattattt tatagtcctt tcatcatata aacctattaa agattatctt
    12901 atttattggt atatgaaatc atattgttta ttattttata atcttttcat catataaacc
    12961 tattaaatat tatcctattt attggtatat gaaatcatat tgtttattat tttatagtct
    13021 tttcatcata taaactattg tattctataa actgatacat acccagctgg agaagtacct
    13081 gtcgtgcctg aaccaaatgt aaagcttaaa gtaacagctg ctgctctagc atcaactaaa
    13141 aagcttaaac ttacacttac atctgatgaa gtaagcgtat ttactgcttt tgcaataaag
    13201 ttattttggg ctactccatt aaagttagta gtaattgaca taaatcctgc aagtgaaagt
    13261 atggcacgta taccaaaaga tacattgtat atccctccaa ctgcaagatt tatagtacta
    13321 cttgttggaa aagttatatt agttccattt ataaatgatg aattaaatgt cactaatgta
    13381 ttattcccta aacttgaaga agatactgta aattgtgcat tgtttgctgc taacactcct
    13441 gttgctccgg tcgctcctgt tggacctgtt gctccatttg ctcccgttgc tcctgtcgcc
    13501 cctgttgctc cggtcgttcc atttgctcct gttggtcctg ttggacctat tggacctgct
    13561 actccatttg ctcccgttgc tcctactgct cctgttgggc ctgttgctcc atttgcccct
    13621 gttgctccgg tcgctcctgt tgctcctgct actccatttg ctccggttgg acctgttaga
    13681 cctattggac ctgctactcc attcgctcca gttgctccta ctgctcccgt tgggcctgtt
    13741 gctccatttg cccctgttgc tccagttgct cctgttggac ctactgctcc atctgctccc
    13801 gttgggcctg tcgctcctac tgctccggtt ggacctattg ccccagctac tcctgttgct
    13861 ccggtcgctc ctgttggacc taccaaacca tttgctccgg ttgctccggt tgggcctgtt
    13921 ggacctacca aaccatttgc tccggttgct ccggttgggc ctgttgggcc tgttggacct
    13981 accaaaccat ctggacctgt tgctcctact gctccggttg gacctacctc tccatctgct
    14041 ccggttggac ctgtggctcc tattggacct gtggcacctg ttactccatt tgctcccgtt
    14101 gctcctatac ttccagttgg acctgttgct cctgtatttc ctgttggtcc tgtagcacct
    14161 gttactccat ttgctcccgt tgctcctgtt gctcctgttg gacctgttat cccattcgct
    14221 cccgttgccc cagttgctcc ggttagtccg gttgcaccat ttgctcccgt tgctcctgta
    14281 tttcctgttg gacctgttat tccatttgct ccagtcgctc ctgtatttcc tgttggacct
    14341 gtagcacctg ttattccatt tgctcccgtt gctcccttgt ttccggttgg acctgttatt
    14401 ccatttgctc ccgttgctcc tgttgctcct gttggacctg ttattccatt tgctccagtc
    14461 gctcctgtat ttcctgttgg tcctgtagaa cctgttgttc catttgctcc agtcgctccc
    14521 atatttcctg ttggtcctgt tattccattc gccccggttg ctcccgtatt tcctgttggt
    14581 cctgttattc catttgctcc ggtcgctccg gttgcgcctc taggccccgt cggtcctgtt
    14641 ggaccagtag cacctgttgg ccctgttgga cctacatctt gatataaact tggacctgaa
    14701 atatcactca tataattaat cctccttttt taaagttaga gtattactct ataaatattg
    14761 agtattactc tatataatta tatgaatcga caatttctta tgtgataatg tatctatttg
    14821 cttatatcaa catatatgct ttgattctta aatttcatta cttttttgta aaatctttta
    14881 caattattag tactctttta caattattaa tacaattaaa aaactcattt cccatcaatt
    14941 atttaaaatt tttttattat gttataaaaa atagataatt aaattgcata aaattaattt
    15001 aatactactt taattacttt ttaaataaaa aaacctcaac acgattaata aaaatcatat
    15061 taaggcatcc acaaaattat ataattgctt atctatcttc atcagtaaca ttgaatatat
    15121 aaggaacatt tctataataa tcaccaaaat caaatccata tccaaccaca aacttatctt
    15181 ctatttcaaa tccacaataa tctggcacta aatcaacttt tcttctgctt ggtttatcca
    15241 aaagaacaca gcattttaaa ctagcaggat ttttagcttt tagatgtttt aacacaaaat
    15301 ccatagtaag tgcagaatca gtaatatcgt ctacaaccaa aacatcatat cctgctatat
    15361 cagtagtcac atctgaaaca actttaacct ttccagtact ttcttcattg tttccataac
    15421 tagatgtagt cataaaatta actctaagtg gtaaatttat atttctaact aagtctgcac
    15481 aaaatataaa gctacctttt aatagagaaa ctaccataag atttttatct ttataatctt
    15541 tttctataat tgctcctaat tcccttaatt tatctttaat tttttcttct gaatacaata
    15601 cttcccattt ttttgtttct atatccataa aaagacctcc aattgtaata atccttctta
    15661 attttataag agattgctca ctttttcaat actcttattc aatattagtc aatattattg
    15721 agtttttatg ttcattcaac aattattaac aatgtatctt atattttaag tagttcatat
    15781 atccacacta aattacatac tatatatttt agacaaaaaa agaaaaaact tgcactaaca
    15841 agttttttct attatacata aatttataca taatcatatt ttattagagg gtactaatta
    15901 aatttattta tgctattttt gttatacctc ataatacaaa acatattata aagtactagt
    15961 caactttatt catatcattc attacattta agattatctc atctgttata gacatacctt
    16021 tgtcacttac tctacctaag ttttgtatac tttgctcaac acttgaacca actataccat
    16081 ttagtggtgg tacaaaacaa tcttgcttag ctattatagc actttgtata gctgcagatg
    16141 ctgcagaaga taattttaat gcacaaccag ctttcgcacc gtcacatatc attccactta
    16201 agtcagctat catattttct atagctcctt ctatttgctt ttcagtacca ttcataagcc
    16261 aagagatacc agcagttgct ccagtagaag cagcaacacc acatccacac acagcagata
    16321 atcttcctgt atagttctta atataaccag ttactagatg agatatagct aaagcctttg
    16381 ctagtttttc atcaggttgt gggaattttt tattataagc aacgattgga agaattgctg
    16441 ttaatccatg atttccactt ccatttgaac tcataacagg catttttacc cctgccattc
    16501 ttgcatctga agctccagca gttaacatca ttgcataatt tataacatca ttacctaaaa
    16561 gaccttcttc tatagacttt ttaattccat atccgacacc aataccagtt ttttgtttta
    16621 atccatattc agccatctct tcattcattt ttactccatc tagtaaaaat tctatatctt
    16681 taaaatcaat ttcttctaca ttttttatta attcttgtat agttactgta tccattaaac
    16741 tttcagcttt ttctgccgca tcatttgaag ctgatacttt tggttcattg tctaataata
    16801 cttctccatc tttttctaag aacgtaaaat tatcatgttt agttcttatt ctcactttag
    16861 caatatgatt ttttcctttt aacacaactt ctataaatac tttctctctt gtatcagcag
    16921 gtgttattga tagtggagta ttatccatat aatcctcagc tattttaact tcttcttttg
    16981 ttagagtttc taacacactt aatccatttt cagaatggcc acctactata cctagagctg
    17041 ctgcaatttt taatcctaat ctttcagtac ctggtatacc tacgcacatg ccatttttgt
    17101 agatactagg actaactaac atacgatttt caactatttc ttctcctaat aattcctttg
    17161 cctttgcaca tgctagagct aaggctactg gttcagtaca ccctactgct ggtttaactt
    17221 ctgcctttaa catttccact aattcttttc ttatatctct cattatatat aaacctccca
    17281 attaagttta gatttagtac tcaaataatt aattaaataa tttcttatct atatttatag
    17341 caaaatacat gccatatttt ttatatcttt ttatattttt agtcttatat tctataacca
    17401 ttggtatgac tgcttctatt tatgtatttt ttttatttac atagagtatt tatattcttt
    17461 aaaatggaga aacatatgac aatttcgcaa aaagacaaaa aaaagtctca gaatgagatt
    17521 ctatatcatt ttgagacggc tcaaatgtgt tattttttaa cttataaaaa ccatttttta
    17581 attcataaaa aaagattatg caaaacactt atagtataag tttaaagctt tctttaaagt
    17641 tatgaattta gaaaaattta aattttatat agctttttat tatattacta tgaaattata
    17701 ttgtattttt caatttttct atataatgta gctcttgata ttccaagtgc tttagctgtt
    17761 aattctttat cttttttata atctttgtac ttatttaaag cttttattat ctcaatcttc
    17821 tctagttcat caagtggaat tatcctatcg cttttaactt ctaactcttc tacagaggta
    17881 ttcttaattt tttgaggaat tacattcatt gtgattattg aagaagaaga catattcaca
    17941 ctatattcaa taatattctg caactctctt atattccctg gccacttata ttccatcata
    18001 gcatcaacaa ccctgctatc tatgtcaata acatttttat ctaatttttt tgaatactct
    18061 ttaaccatat gcttgattat aagtgggata tcttcttttc tctctcttaa acttggtaat
    18121 tttataggta taacatttaa tctataatat aaatcttctc taaaagtgcc attttgaacc
    18181 attttttcta aatctttatt tgtagcagca ataattctta catctattga gacatttgat
    18241 ttacttccaa ttttattaag ttccttttct tgtaatactc tcaataactt tgactgtaaa
    18301 tgcaaactca tatctcctat ttcatctaaa aatatacttc ccttatgagc tacttcaaac
    18361 attccaagct ttccaccttt tttagctcca gtaaaagctc cctcttcata tccaaataat
    18421 tcactctcta ataaattgtc tggtatagca gcacagttta cagctataaa aggattatct
    18481 actctattgc tatggttgtg tatggctctt gcaaatagct ccttacccgt tccactttcc
    18541 ccagtaataa gtactgttga tgttgattta gaagctatta gggcttcctt tttagaattt
    18601 cttatagcta cactttctcc aattatgttt tccaatttta ttctataatc tttattcatc
    18661 ttattgtagt tttttatagc atctctttta tctataaaat caataacata tccctttaac
    18721 tcatttttta atactatttt attgatgttg tatattccct tcgaatcata tccgtatctt
    18781 ttataaaaaa aactacacga tttgtctttc ttaaagttat ttatagaagg tttctttata
    18841 aaatctaatt cgacaaatat gtttttgcca gttatactat cctttatatt gaaaagctct
    18901 ttaaattttg aattatattt atcaattttt ccatccacat caatagacac aacagctttg
    18961 tccatattgt ttaatagtgt ctctaatttt ttcttttcta attcaagctc ataagtttta
    19021 atttgtgctt ttaatttatt agatattaag tctgccattt tgcctaaaaa gtttataaga
    19081 ccacttttat tattttctat aatttgtgct tgttcttttg taaaggctat aaggcctata
    19141 acgccatgag aatcgccatc acatataata ggacaacaca cctctgcaaa ctctacacaa
    19201 gccccacttt tatagcattc cctacataca tcactactct ttgggtcatc aattagtatt
    19261 gtaatctgtt ctgtaagtga ttttttaaaa gccgtatatt tatctacttt ctcacctatt
    19321 ttgtctatat atactcctgt acctgcaatc ctaaataact ccttatttac tatagttaca
    19381 tctatattga gtactgatac tatagcttca gctatatttt gaatatcaga ttttatatat
    19441 tctaaaccta tcataaccat cattccttat ttttctttaa cataagtatt tgtcttattt
    19501 ctttaagaat caagtatatc ttatttaaag taaattggat tgacatcagg attacaaaga
    19561 gcataacaat tattattaac tcataattta tttccatcta aacatctcct tataacaaaa
    19621 gactaggctt aacctagtct tttatattat atccatattt atattttaac tcatttatct
    19681 tctttttccc acataaatat attttaattt atttgactct ttaatcatac catcaaagtt
    19741 taatcttgaa aatatattaa atacttcatg tggatagtga atctttgcaa cagaaccaca
    19801 aaatttatgt ttaagataat ttaacttaac ttttaaattc tttaaattta aatcctctaa
    19861 tataacctct ccattgccct ttaacactct ttgtatttca gatgaagctt tttcacaatc
    19921 tgtaataaca ttaaattggt caactattat tatcttgttg aactgattat catcaaatgg
    19981 tagaaactct aacttacctt taactacatt gcaattttca ttatacacta gagaataaca
    20041 gacatcttca taattactat tctccagtat agttacagaa gttccaagac ctctcaatct
    20101 cttgcctagg tttcctatat gaccaacaag caatatttta tcacctacat tatactcaat
    20161 tgtatccaaa aaacattcta attcatcaga tgtatattta gctttaactg gctgtttatt
    20221 tatctgacat aatatgcttt tcacaatgct tcacctcttc atttcctcaa ttataaatta
    20281 tgtacagatt acattataat aaatggcgag caactattca agagatattt cattagtatt
    20341 tttttaaaca atctttatac attttaatat gatattatac caaatttatt aggattttat
    20401 tcataaaaat cagtctattt tttatgttta ttcattgtta ttttcatcca atttttttat
    20461 tttcgatatg gatacttcat atgccatttt tttgaccaca ttattttcat ctattttttt
    20521 ctcatattct ctactttgaa ccctacccca aagctgtatt ctatcaccaa cctttagatt
    20581 ctttgcaaat ttagcatttc taccccaaac tattgatggt atataatcag atttattata
    20641 aggtctgttt atagctacta ataaatcggt tatttccctt cctaaaggtg tcttcctata
    20701 cacaggttcc ttacatacat atccatctaa aaatatacta ttagggtctt tattttcctc
    20761 gtctatgctt tttatttctc tgacaaacac tgtaagcact aatctatttt tattatttaa
    20821 tgttttgtta tatgatctta attggcctac gacattgact aaattttgtt tatcaaggtc
    20881 aatatcttgg agaagtcttt ctgatacagt cattggaagt atatcaaaag aatcgcttag
    20941 tctgtttatt tttattttca tattataaaa tttttctcca aatatctcat ggctaaattc
    21001 tagcttattg tctaactccc ctcttaagtt tactacgtta ttctcatctt taacagctat
    21061 catattttat ccctccacaa ttgttaattc ttatatttct ggtatcagct tatataataa
    21121 atatatttat aagggatgta ttttattaca aatctttgat tgctgtttaa aagtttttat
    21181 ttagttataa atttcattta atatttcact tttataatta taaaattatt atctttttgt
    21241 actacatata ctaattaaac tacctatttc agttttgtat taattataaa aatcctatta
    21301 tataattaat aagtcatata taacttaaat ttattcactc tatataagca acttcaacga
    21361 attaaattta ttcaaataat tcagatgaat attgagtcat tataaactta tttttcttaa
    21421 ttataagtta tattagactt attacagctt atatttttat taatctgtat taatatatga
    21481 acatttattg aacttattga ttataaaatt taaatattta gctttaaatt atgctttatt
    21541 ctttaaaaat acaacgtttt ttacattaaa tctactaaat cactatatat attacataat
    21601 tggcatgtta attgctttat attaatttag caaataaaaa actgccctaa aatattaatt
    21661 caatatttta aagcagttta taatctttat tattagctgt aatatttaat aaacactaag
    21721 tagtctttaa ctaagcagtc tttttgtttt tatttgcagc cattatcatt gtagcagaag
    21781 tataagctat aactactatt actaatgctt ttaatatatc cattggtaga gtttttacta
    21841 tatatgcagc tacgaaaact cctattaaac cacatatagc tattataact gatgcttttt
    21901 tagtatatgc atcttctttt ataaatttca tacttgcaac tggcattaat aatgcacaag
    21961 aacccataac tattgggaat gcaacttttg cagacattcc taagaaataa accattgcca
    22021 tacctggagc atatagacct ataccagctg tcattaaagc tcctagtata aagttaccta
    22081 ttacacctat taccaattta acaccagtaa gacctaattc atttcctcca cctggtaata
    22141 cgttaatcca aggatgacct aataacatta atattgctgt taatgctaaa gttacaccca
    22201 taacaagttg tatttttctc tcgtccatct tagctattat tcctgcacct atatatgaac
    22261 caactgctgc tgccacaacc atagatacta aagtaacacc atcaactggt atgattgatg
    22321 taaatatgaa tgcttctgta acaactggaa tagtatgtgc tacgtttaat gtaccaggca
    22381 tttttttatc tggtatattt aactttaaag cctttgacat tgctattgtt ggagcaaatg
    22441 accctattcc taatgtatca aagaagtctg ttataaatcc tgttacagca acttttggag
    22501 tactttgttc ttctagtttc ccctctttgt ttgctttagc tacgtcttta ccaaacacaa
    22561 ctgcaaagat tgctgcgaat actacatata atgcctttaa gattgctacc ataatccatc
    22621 ctcctatttt tttatttttt catatattct gaatcttata gcctaaaagc tatagaatag
    22681 cagccgacaa gtggctacta ttctatttta atttcctaat ttatttatta cttatttaag
    22741 aataaatcca tgtttaagtg ggtcttcttc atctattaca aaatgattaa atccagttat
    22801 ataagcagaa ccagttattt taggtactac agcattgaaa tctgcaactt tagtttcttc
    22861 aactatttca cctttgaata aagttcctaa tatactttca tatacgaatt tttctcctac
    22921 ttttaattca cctttagcat gtaaagtagc taatttagca cttgttccag ttccacatgg
    22981 agatctgtca acttgacctt gaccaaatat aactacattt ttgtaagtag cttctggatg
    23041 agttggctca tcatatattt caactaagtc tacagttttt atatgagcta aagttggatg
    23101 ttgtatttct attttctcat ttattatatc tctaagtttc atagctagtt cagttaattt
    23161 accagcattt tgaggttcga tttttaaacc taattgactt gcatgtatta tagcaaagaa
    23221 gcttccacca aatgatatgt caaatttaac agtcccaaca cctggtaagt caacttcaac
    23281 accttcttta tataagaaag ctggtacgtt taagaatgat acttctttag cttttccatc
    23341 tacaactgta acgtctcctc ttattattcc tgctggagct tccataacta catgagttac
    23401 aggctctact gctggaacta cacctgtttc tatagctgct gtcatagctc ctattgtacc
    23461 atgtccacac atgttaaggt atccgccacc atccatgaag attattccaa agtcagcatc
    23521 tgggcaacaa ggttgagtca ttacagaacc aaacatatca ttatgtcctc ttggctctaa
    23581 cattatagca gttcttaaat aatctagatt ttcctctaaa tattcttttt tctcaggcat
    23641 agaatttcct tttatgttag gtattccacc tacaactatt ctagttgctt cacctgctgt
    23701 atgagagtct atagcttgta tacttctgct aaatttcata tcaaattccc ccttaggttt
    23761 attttgcgtc tttacgcatt tttaatttta ggaaagccta tgctttttta acatcaactt
    23821 catccatgtg attgtctcca actacttctg tttctatgta gcctgttgtc tttttataat
    23881 caattatggt agctttatcc aaatatggat tggtaattac taatccatct gctcccataa
    23941 tagtaagacc tactgcaggt atatctgatt ttacaaactc tgctatagca tttgtaaaat
    24001 caatgtgctg gtttcctgcc atatctaaag ttataatcac tccatcaggt cgcaatgatt
    24061 caatccatct tccaagtcta gttgctaaaa atgttttcca ttcattgtgc tctgatgtcc
    24121 caactacaac cactcctaac aagtctatgt cagaatcatt atctatcaaa tctagtaacg
    24181 ggtctctaaa tatatgaagt gatgtgtttt tcattgatgt agaaattccc acaaaactca
    24241 ttcccttact taaatttttt atccatgttt tctcatttta agttttaaaa atgctaaagc
    24301 ttttttagca tctatttcat ttgtgttgtt ttctccaact acttctgtct caataccttc
    24361 ctttgatttg ttcatatcaa ctatggtatc catatattga ttgcttacaa caaacttagc
    24421 ttgagtccca ttaaatgtaa ctccaactac aggtatatct ctttttccta tttcctcaaa
    24481 tgtgttagcg tagtcaacat gtgagtttcc ccaaccatct gatgaaacta tagctccatc
    24541 tactctcatg gcttccagcc aagcggccgt tctttgtccc acaaaggttt tattttcatt
    24601 tccatctgga gttcctacta ctattactcc aagtaaatct acatccttat cactttcaac
    24661 tatgtctaaa agtgggtctc taaagtgatg aagagatgtt tcttttgttg aaggtcctat
    24721 tcccataata tccacctctc ttaagtcata gctctaaggg caccatctct gtattcatta
    24781 ggagatataa tcataggtac atttcccata tctataattg atgttcctcc ttcaaatcca
    24841 ctaggttcct ttgagaataa ctgattgtca tacatagcac cttgacctgc tatttgtttt
    24901 actatgacaa ccttttttgc atttggtcga attttgtcaa aatattcacg aacttgagta
    24961 gcatttcttc cgtcttccat tttcaaagac gctcttattt cttgtataaa atcatcacat
    25021 gctctgaatg ctgcaagtgg aagtgttctt tcaaaaggta aacctccctt taaagttaca
    25081 tctacatgga ttatataatc ttcaactgat ggagttccat atctcccaaa taccatttgg
    25141 tctttcaaaa ttccttctga agaaccaaat tcatgcattt gatttccatc ttcatctgca
    25201 ccagttaaca ttacatatac acccgttaaa gtatgtgtga taccctctcc cagtctgcct
    25261 aaaacttttg ttgatattgg tataatgtcc ataatagtat taatttctct atcataatct
    25321 ccaggtttta taatgtctac ttttatgtct gttattaact cttctctttc ttttatttca
    25381 tctatacttg ataaatctat tgtaagtaca tctttcttta tagaagtttt tgaaccgaaa
    25441 ttaacttcat tcatatgaaa cggttttata acaagtcttc tcattatttt ttcttccata
    25501 atatccacct ttgttcttaa aacccctctc ctaaccgtgt aggagaaggg ttctatattt
    25561 tcaaatataa attacatttt aaacgtgagc tttatattcg tatggtaatg gaactatctt
    25621 accagcagat ggtattgcaa ctaattgctc taatgtatct cttaatatat gtgtttgcat
    25681 ttctatatta tgtggttcac cagcattagc acccattgga actaatggag caactgctct
    25741 aggagttccg ttttgtctaa ctactggagg aagagctgct attattattg taggtattcc
    25801 agcttcctct attgctctct gcacgatcac ggcagttcta tggcaagtac ctcagccagc
    25861 tgtcataact acaccgtcta ctccctcttc cttaagttta gcagcgatag caggaccagt
    25921 ttcttcagtg aagacatgtt ggtttcctcc accacccatg aatgcatagt gcataggagc
    25981 tactcctttg ataaatcctt ctgcagctaa ttcatgtaat ctatctatag ggaacataca
    26041 gtttatatct ttgtttacat ctccattgtc atatccacca tgtgatacca tcatttcatc
    26101 aactgtagct gtattaggta tagctctaaa tgtagtatct cctgctagat taaatctctt
    26161 gtcagatttt aaatgaacac cagctgctgt agctaaagct atagtcatat cttttaattc
    26221 tttagttaca ggagtccaaa ctggaggagg tgttattgga acgaatattt cagattgaag
    26281 tccttgtact gttgtaaggc tcatatattt cctctccctt ctattttcaa acgattattt
    26341 attatttttc ttcttgtttt gattgcattt ctgcttgttt ttctttttct ctactaatat
    26401 tttctacata ctcttgatta ggctctggac ttaatacctc aggatagctt agcatgaatc
    26461 caacttcttg acctatctta agttcgtagt cagttataag cattctatta ggtattttaa
    26521 attgtccaag tctacctttt aggtctatag tcactccacc gcctttgatg tcaactataa
    26581 taccttcata aaaagtctct gatgagatat attttaacct atccattata attctacctc
    26641 tctatactgt tttaaacttg gatctaaatt tatgttattg tctaaatctt agttagtatc
    26701 taaattttag ttttcgtctt tttcgtatat ttctcttctc ttcttactca ttggtagaga
    26761 ttgctcattc tcttctaata ctattttttc tcctgtaact ttttctatag cttctatgtt
    26821 atttaattta acatttggat tccattttct ttcaggagct ttaacttcta caccttctat
    26881 agcattttta agcatagcca ttattctaac agcatcttct ggagctaaag tgttgttaga
    26941 taatatttca ttctctatac cttgcttaga cttattgttg tctaccatgt gagtcatgta
    27001 tttattacca acaactagag caccttgaac agctgagaaa cttacaccaa ctactggtat
    27061 acctctcata cctatttgct ctatgtgaga tgcgaaatct atatggttgt ttccgaaacc
    27121 ttcagtagtt actacagctc catcaacttc catagcttca actaacatac ctaatctctt
    27181 agatacatag aatttctcag catttacttg tggagaacca acaaatacaa cacctactaa
    27241 atctatttct tcgtcttcca tagctcttat tactaatggc tctctccagt aatgtcttga
    27301 catttctttt gatgcaggtc ctatacaagt taatgcatgg ataccaccat ctaatacttc
    27361 aagtggagat aatacaactg gcatatttcc taagtcaacg tttggttgag ctcctaatgt
    27421 accaactggc tcaactggta atattaggtt atcatgcatt gcaccttgtc ccattatttc
    27481 ttttataaca acaactttct ttttaccttc tcttctgtat tgctctatta cttcttcatc
    27541 aactactaaa gagttgtcaa ctttctttaa tgcttctctt atttcttgag ttacatagtc
    27601 aaatgcacgg tgagcagcta aaggtcctgg tctttccatg ttagttcctg cttttattgt
    27661 tacttgacct ttgatgaata tttcaccttt gtcagcagca cctggtctac cccacattat
    27721 agtagtattt aactcacctt ctgaagaacc aaattcacct atttgaactc catcttcatc
    27781 tgtaccagtt aataccatta cagctccatc tataactcta gttatacctg aacctaattc
    27841 gccttcttct ttagtagcga ttggttgtat atctaataca gcttcactgt aagtttcata
    27901 tttatcagga gttattattt ctaacttcat atctacaact aactcttgag tttcattagc
    27961 ttctttacat atttcttctg cgtttctgat gtataaagta gttccttcta ttttagtttc
    28021 atcagcaaat tcaactttat ctattttaaa gtgtttttta gttaagcttc ttaaaagttt
    28081 cttttcttca acttttggag ctacttctgc tgctgcactt gccactggag cagcaacgtt
    28141 tgctactgga gcagcaactc ctgcttgacc agctactgat aaaggtatct ctaagcttat
    28201 gttcttacct tcacctatgt gtattttaac tgtttcacct gcaactcctg tgcttactgg
    28261 aactactgct gcttctgata ctggagctgc ttcttctact gtttcttcta ctacttcttc
    28321 tttagcctct cctgctttgt atccttctac gttatctgta gtcattggag aaagtgcatc
    28381 taaagtttct tttaacttag ctcctagtac ttgacctata gttaatccat tttctggtat
    28441 tgttaataat ccagaatcct ctaagtctgc aaatattgct ggatcttcta agttttctgg
    28501 cgctataatt gttcccgctt caaatctaca acaacaaact gctgggtcat ttgcatgggc
    28561 ttgagctgtt tctaaagtta ttgacatagt ataaaatacc tccttacatt attttcttat
    28621 ttattatttt aaatctcaat tcctcaacag gtaacccctt aactgagaaa ttaagtaaat
    28681 taaaacctac ataatttgtt atgattaata ttattttttt ctcactcaaa gtcactttat
    28741 attataagca attcctatgc caacttatta acaaaaagat tttttctata atagattctt
    28801 catctatcgc tatttttagc caaatattat ataaatattt atttaaaata tgttattttt
    28861 tgtatttgta aacattttct caaacaaaaa aagtgtcaat taatcaacac tttttcattt
    28921 tttttaacac atctatatac acaacactta tacaagtgtt ggctttacta ggttttaaat
    28981 taaagtttat cattttgtca aaatttagtc atatgtcata ttttagacac atctattttg
    29041 tattggtcta tcttataata caaagttgtt ctgggtatat ttaatatctt agctgcttta
    29101 gctttatttc cattagacat tttaagtgcc ttggttatat tctttatttc aattttttga
    29161 gttgccttcg ttaaatctaa gggatactct tcttcttcag tactattatt tgtagaatcc
    29221 atcatataac ttggtacatc atctacatct attttagaat tttgtgacaa tacaacaata
    29281 ttttcaatcg tattttttaa ttctctaata ttacctttcc atctataatt ctgaaatata
    29341 tctattacat ctttgctaat tgtaagaaca ggcttattat tttgtttaca tatctcctct
    29401 aaaaagctat gaaccaataa tcctatgtct tcttttctct ctctaagtgg aggaatcttt
    29461 atttcaacaa catttaatct atagtataaa tcttctctaa atttttctgc ctttaccatt
    29521 ttactcaaat ctttattggt agctgatatt attctaggat ttatttttat tgtggtatct
    29581 ccaccaactc ttcttatttc tttttcctgt aatactctaa gcaactttgc ttgcatacta
    29641 agaggtaaat cggcaatttc atctaaaaat acagttccat cttttgcaag ttcaaatata
    29701 cctattcgac cctttttact tgctcctgta aatgcacctg attcataccc aaaaaactca
    29761 ctttcaaata actcatttgg tatggcacta cagttaacag gtataaattg accttttctc
    29821 tcactataat catgaatagc tcttgcaaat acttctttac ccgtaccact ttcaccccaa
    29881 ataaatatgc tactatttgt tctagccact tgttttgcaa tcgctttcga tttttccaat
    29941 ttataacttt tacctaaaat cttatcaaaa ctacctttag ataaattttt gacttcgttc
    30001 tttagatatt ttaatgtatc atttactttt tcaagttcaa gagctaatat cttagcttct
    30061 gtaacatcaa cttctgtaca tacaacaccg ataaattctt ctttataaaa tataggattt
    30121 gcatgaacta atgcatacat attttctttt ttatctgtaa aatacaagtc actcattcca
    30181 actttactat ttagtacttt ttctgaaata gtattttcca aaaattcatt catcggtcga
    30241 ccaactatat cttcagactt tatatcatac ctttcctcca taaacttatt ccacaagata
    30301 acaacacctt cgttatttat agcacaaatt ccttctttaa tttgacctat aatatacttc
    30361 aaagtcaatc cataatcttc taaatgcata tatagatagt ccctaatgtg ctcttgtttt
    30421 agaactccaa taattttatt atctctaaga acaggaagaa tccctatatt ttttaatatc
    30481 attatatctc tacattcatc taaggttaaa ccttcgttga catatattac atccttcttc
    30541 attataagtt ttactggttg accttcatac tttttatgca tctcataaag attatgtata
    30601 tccgtcatgg atataatgcc ttttaattgg tcagatgaat ctattaccat tagagttttt
    30661 gtgttgcttt ttatcatttc ttttattgca tcttcaattc ttgtgtcttc gtctatagtt
    30721 gtaaattttg tatccattac ctcttctact ttttttactt ctggtatcga aaacataaag
    30781 tccccccttt atagtagtac c
//
LOCUS       DACTZW010000042        30651 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.042, whole genome shotgun sequence.
ACCESSION   DACTZW010000042 DACTZW010000000
VERSION     DACTZW010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30651
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.042"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            132..2033
                     /locus_tag="JAM15_10535"
     CDS             132..2033
                     /locus_tag="JAM15_10535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HAT6798690.1"
                     /translation="MRERIILETLKNSSGYLNIDYFADKLGVSTRTIRNEIKKIETIK
                     ECNGFKLEYKSKLGYILNIKDQDKFEHYLRNLPSDLVENPEQRLESIIVELLVNEGYK
                     TIEQLSKKFLVSSSQIKNDLKKIDEKIKDTELKLERKAHYGIKIEGSIKEIQSILVDS
                     YFRGNRNITEYRNKFIDNLKLANIRSTIKNVLNEHDLEANLTELEEILAQIIILYIRV
                     SMRVVGNASNLKLYTEDLIIDKLLDKIFRDKKYNLNYDEKYYLKELIKLKTKDKKATI
                     KNIDKNKLQDIMFEFFREIDKKYNSNFLEDKEFFNLFYLHIACLIERIKKNHKIINPF
                     SVKISQQYPTVFNLSIQFSKIIENEYHIKISQDEIGFIATHIAVPFEKREEANFNKKY
                     KIAIICSSGGGSAFLINLRLKEIFPNAEIRNFSLLEEKAVIEFAPDLIFSITNLLFEI
                     NAPVILINEILDELDYLDIKESVRFADHIGNISSPKQYILGLFDKNHFRCIKDKAKYK
                     DILDSMSKCIVDEGACSPTYPKDVWERESYLSTIYTNGVAIPHPIEMTGNKNIISVAL
                     IQTDIIYENRVPKIIFMISLIKGNLELHKQISKYLSKIMVNKDMVDMLNKSQSYEEFM
                     YKLKIYLGG"
     gene            2036..3079
                     /gene="ypdE"
                     /locus_tag="JAM15_10540"
     CDS             2036..3079
                     /gene="ypdE"
                     /locus_tag="JAM15_10540"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HAT6798691.1"
                     /translation="MNIEFFKRLSEADGIASNEEEVRHVLLEELKVYSDKIICDGLGS
                     IIFSKIKDESAPNVMICAHMDEVGFMVRSIDKLGMIHLITIGGVKPLAQFVQKVRITT
                     KEGKKIPAVINATYNNGKAENIYADIGAYTEEDVYNLGINVGDMVTYTTSFEEFTLPD
                     RLVGKAFDDRIGCFVMGEVLKELRKENLNCNIHFAATSSEEVGIRGAKTSTQLINPDI
                     VFVIDVACAKNEFVRDYTNQKQIDKGVMLMHRDRTLVPSRKMIDYVMEIADKNNIPLQ
                     HDMFESGGTDGGEAHLVNEGKPCVVTCVPVRYGHCAFSIVSNKDLENIIRLYTQLILN
                     FDEEQYKHIRNFI"
     gene            3094..3399
                     /locus_tag="JAM15_10545"
     CDS             3094..3399
                     /locus_tag="JAM15_10545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAT6798692.1"
                     /translation="MSTEVQIMELISTAGESKSKAFEALKKVKSKDFKGAKLLIEEAR
                     KIDIEAHRIQTELITQDLNEDVESPTMSLLMVHAQDHYMTSQLAKDLIEALIYCLDK"
     gene            3496..3831
                     /locus_tag="JAM15_10550"
     CDS             3496..3831
                     /locus_tag="JAM15_10550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAT6798693.1"
                     /translation="MKILLCCAGGFSTNMLMQNMKKVVKESAKLNEKDFEFTAIPADS
                     IESEVDDWDIVLIGPQIAHKIDFLKGILEPKNKPFAVIDKDVYGKMDGATVMKLALIT
                     YKKHQLAQG"
     gene            3863..5185
                     /locus_tag="JAM15_10555"
     CDS             3863..5185
                     /locus_tag="JAM15_10555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010492767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAT6798694.1"
                     /translation="MFSKFEAFMNRVFMPLAHKVDNQRHLGSIKAGMVAMTPFTILGS
                     IFAILPALPNMLGENNPISKFILNNSAILDLPVSLSIGLIGLYACMCIAFNLGNYYKL
                     YIPGCVALSTFSFLFLVASFTPDGALEIGNLGAKGLFTGMIAGLGSVELYNFCNKKNI
                     TIKMPENVPDFVSRSFELIPTTIIVCGTFIVARFISLKVFGELPPQILTQFLSPLVGS
                     MDNPWSVLALNFAICTIFFFGIHSSVFSPITRPIMITFIAENIAAMQAGETIPHFFTA
                     GASSAFFGFTGCGISIGCVIACMLSKNASYKKIGRVSLFPALFGINEPILFGAPIILN
                     PIMFIPHVFGGAIIGTLPMFFMHWGWLAKPVFDPPYVGVFLEGFLTNGDWHSILANAL
                     QLVLAVLLYWPFFKIMERQQNNKKQKEETKNIFSKEEEDLLDDLGLDF"
     gene            5195..6265
                     /locus_tag="JAM15_10560"
     CDS             5195..6265
                     /locus_tag="JAM15_10560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HAT6798695.1"
                     /translation="MNNTIERLVSLIYKRGVDALLIKAKNTKRYIGALSGSGVYVLVT
                     KDKNYQILDGRYIDEADKKTTGFIKRIVSQGSYIPTIIELLKELNIKKLAIENQAMSI
                     QEYLSLKNEGFEINLITNELWKLRAIKSKEEIELIKKACEITDEVFDEVISEIKKDMT
                     ELEVSALIQYHALKKGASGMSFETIVVSGERGAMPHGRPTNKKLKVNEAITIDFGVVY
                     QGYQSDMTRTISIGKPPKIIKEIYDVVLEAQLSAIESIKEGTRASDVDKVARKIIDKH
                     GFGEYFNHGLGHGIGLGDGEVPTLNPNSEDILVEGMVMSCEPGIYIPNVGGVRIEDDI
                     VIIDGKGVPLNKTSKEFIILGE"
     gene            6270..7457
                     /locus_tag="JAM15_10565"
     CDS             6270..7457
                     /locus_tag="JAM15_10565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAT6798696.1"
                     /translation="MKYNFNKVLNRKEGNCRKWSNHVIKEKFGLNEDAIPMDLADIDF
                     ECAPAIKESILKRASVGDYSYTFIGDDFYDAIINWNKRRFDVYIEKDWIKLTFGTVST
                     LHYIVQAYTKEGEGVLINTPAYDPFAEAVANNNRKLCCSSLKLDNNRYYLDLEDMENQ
                     MKYENIRLLIFCSPQNPSGRIWTKEELYQVSELCLKYNVILVSDEIHRDIIFKDYRFV
                     SLWNAHPEIYKNSIICVSPNKGFNLGGLKTSYVLIRDVKIRETLLERLKSNSITSPNV
                     FAIPAIVAAYNESEEWLDAMTSYVGENFEIVYDFFETNIPKAKVMKSDSSFLAWIDVR
                     EVFRNEEESKEFFRHANLTMVVGSYFVKDGDGFIRINVGCPRETLNEALNRIKKTYIS
                     MYC"
     gene            complement(7654..8526)
                     /locus_tag="JAM15_10570"
     CDS             complement(7654..8526)
                     /locus_tag="JAM15_10570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HAT6798697.1"
                     /translation="MNILQNENLIIESSSFGAELTKIFSKKYDKNILWDGNKKYWGRQ
                     SPILFPIVGKLFDNETIIEENLYSMTQHGFARDMDFEIVDKGDTFVSYKLTDNESTLK
                     KYPYSFELIINYTLNDNSIEVEWIVKNTDSKDIFFSIGGHPAFNLPFYEQNDFSKHYL
                     EFKSKNDVEKINLNGSFTDDIIPIGKLKNLHLNPEVFKNDALIYTNIDEVSICNNDGS
                     KYVTISMEDFPLVGIWTPYYSETNSTAPFLCIEPWYGLADSINSNKIYKDKKFINKLS
                     KGKVFTASYNINIH"
     gene            complement(8920..9111)
                     /locus_tag="JAM15_10575"
     CDS             complement(8920..9111)
                     /locus_tag="JAM15_10575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798698.1"
                     /translation="MDDFSKLKSLYEDGYRCIYHDCVDNNYTIYLKNFYTEGSETIEL
                     SSESDFSQFKDYIDGLRMS"
     gene            9331..10377
                     /gene="cobT"
                     /locus_tag="JAM15_10580"
     CDS             9331..10377
                     /gene="cobT"
                     /locus_tag="JAM15_10580"
                     /EC_number="2.4.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /protein_id="HAT6798699.1"
                     /translation="MSLLESISKNIYSLDNSSIEKTKQRLDRLIHPTGSLGKIEDICM
                     QLAGIFGNENFDTSKKVIIAFAGDHGVYEEGVAPDPQNITKLQFPNFSKGLCGVGVIS
                     KFVGADVVAVDVGINCDEKLDGVLDYKIRKGTSNMAKGSAMSKQEAIRCLEIGIEIAE
                     QCIEKDYKVIGIGEMGIANTTPSTAIISVISGCDPLEVTGIGAGLKKERLKHKAEVIR
                     KAIEINNPNPTDGVDILSKVGGFEIGSMAGVILGCSANRIPVVIDGFISYAAALIAYK
                     INPKTREYMIASHLSAESGTKRALDILKLDPLLNMDMRLGEGSGAALAFDIIEASNYT
                     YKNMATFDEIDMGR"
     gene            10409..10969
                     /gene="cobU"
                     /locus_tag="JAM15_10585"
     CDS             10409..10969
                     /gene="cobU"
                     /locus_tag="JAM15_10585"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HAT6798700.1"
                     /translation="MSKIILVTGGARSGKSNFAEKLCFDRNNNTAYIATSIPFDDEMK
                     DRVKKHQENRPRNWNTYEIYEDIYSIIKEIYKEHETVILDCVTLLVNNLMFEHNLNIE
                     ESSQEEINKLEQYIKEQVVKLIEEIEKTNLYFVFVTNELGMGIVPGNKLSRIYADIVG
                     RINQYIASKSNEVYFVVSGIAMKIKE"
     gene            10979..11752
                     /gene="cobS"
                     /locus_tag="JAM15_10590"
     CDS             10979..11752
                     /gene="cobS"
                     /locus_tag="JAM15_10590"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HAT6798701.1"
                     /translation="MKRFILILQFLTRIPIKLNVGFDDEFYKSIVYFPLVGFVIGILS
                     YLIGWISMLLFEPFIASIIITLAGVLITGGLHIDGLGDTFDAIYSYRDKEKMLEIMKD
                     SRLGTNSLLAIMFVLLLKVGFVYDIISNNSLWIIIFMPMIARLGVMLLTYKTVTPREK
                     GMGNLFIGKLTTSMLITAIIYTLLIVALITKFIFLLPNIVLIKVLGSIIVVFVFIILF
                     KKHIYKKIDGVTGDILGCGIELSELVYLIYIYLLIFMFF"
     gene            11772..12386
                     /locus_tag="JAM15_10595"
     CDS             11772..12386
                     /locus_tag="JAM15_10595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAT6798702.1"
                     /translation="MIRLILIRHALTNDNKKGRLSGHINSCISEEGKLQINKITRYLS
                     NENIDKVYTTPSTRTKDTVEKISKLKLLEIEEKEALREISFGDFEGRTFEEIKIKYPN
                     EFEKMIKEGNNYRYPNGESLIDSYKRVAKEIDNIILENDSNLDTKTILICSHAGTIRN
                     IITHLISGSYKYHWNFKIDNASITVLEIDGGFAVIDKMNFTDFI"
     regulatory      12453..12632
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            12747..14261
                     /locus_tag="JAM15_10600"
     CDS             12747..14261
                     /locus_tag="JAM15_10600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyric acid synthase"
                     /protein_id="HAT6798703.1"
                     /translation="MGKKIMLQGTASNVGKSVLVAGLCRIFKQDGYTVAPFKSQNMAL
                     NSFITKEGLEMGRAQVFQAEAAKIEPIADMNPVLLKPSGNNKSQVIVRGKVVGEMPSS
                     KYHDYKLELVGVLKETFNSLNSRYDIVVMEGAGSNAEINLKDRDISNMGMAEIADAPV
                     IIVGDIDRGGVFASLAGTMLLLNEDEKRRVKGVIINKFRGKKELLQDGVKMLEDIIKV
                     PVIGVVPYTDIKIEDEDSVTTRFKKKMNKSDIHIEIIRTPHMSNFTDFNIFETQEDVS
                     IRYVDYGESLGNPDILIIPGTKSTIDDLTYIRKSGLESQIKNLHSQGKLIFGICGGYQ
                     MLGKKLKDPYHVESEIEEVDGIGLLDTETTFEKEKTTTQVEATIVECISEYMNNLKGK
                     KVKGYEIHMGITKRGNDVRSLDLVTKKLDKEVNYTEGSVNKEGNVIGTYLHGIFDEIS
                     FTRAILNNIRKKKGLGELESKVNSFNEFKDKEYDKLADFLREHLDIEKIYEIMK"
     gene            14300..15676
                     /locus_tag="JAM15_10605"
     CDS             14300..15676
                     /locus_tag="JAM15_10605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyrinate a,c-diamide synthase"
                     /protein_id="HAT6798704.1"
                     /translation="MKKILIAGTNSGVGKTTISLGIMQALVKRNMKVQPYKVGPDYID
                     PSYHTFITGRHSRNLDSYMLDDEKIKYIVNKSSKDADISVIEGVMGLYDGFGIDLDNC
                     TSSHTSKVLKSPVILVINGKSMAASSAAMVLGYKELDKDVNIKGVIVNNVKTNSHYQI
                     IKSSIEKYCNVEVLGYFPPNNKFSLESRHLGLVPSVEMKSLREKFYTLADEIEHYIDI
                     DRIIEISESDEFESDFDFQTLIENNKIKEHVNNKSIAIAYDKAFNFYYRENIELLEEL
                     GLEINYFSPLEDASVPNADYIYIGGGFPEIFGKELEANESMRTSILEAHNNNIPIYAE
                     CGGLMYLGEKLLNQEEQEFNMVGIFSGISKMTSSLKRFGYCIGVAKENTLLSKKGESI
                     KGHEFHHSIFESDEKCVYSMRKERDGNIVEEWDGGYSKGNTLATYLHTHFYNNLNCIE
                     NFLKKGNE"
     gene            15677..16648
                     /locus_tag="JAM15_10610"
     CDS             15677..16648
                     /locus_tag="JAM15_10610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HAT6798705.1"
                     /translation="MSILSIYIGYVTDLIVGDPYSFPHPVRFIGKLINFTQGIIRKVS
                     KNDRQLKFGGFILWFITVGITYLTTYAIVKLFSFNILLSIVVNSFIIYTTLATKCLKD
                     EALKIYNVLKTEDIEKSRIQLSYIVGRDTTNLSEPEIIRATVETVAENTVDGIIAPMF
                     YAFIGGAPLAMAYKAINTLDSTVGYKNKKYKDIGFASAKIDDIANYIPARISVILMTI
                     GSFFLNYNYRNCFKISIRDRKNHKSPNCAFSEGAVSGALGIQLGGTNVYFGEKVYKPT
                     IGDKLREIDKEDIIKTNKIMYVSSFVSMLVFTLIHVLCRMILINLII"
     gene            16680..17750
                     /locus_tag="JAM15_10615"
     CDS             16680..17750
                     /locus_tag="JAM15_10615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HAT6798706.1"
                     /translation="MKDLGHGANVGEMARLYGKNPKEIIDFSSNINPNVLPNLERYIL
                     KGLEECRNYPDINYTNLRENISKYIGINPDFIIPGNGATEVIYLLMKSVKKKLAIINP
                     TFSEYRRSAELNNLDIIDLELDLENNFKLNIDIIKENIKRFDSLFICNPNNPSGNVQD
                     LKELVHLLGKHNKVLIIDETFMEFVEDESKYSLVKYIESNKNIFIIKAVTKFFGMPGL
                     RLGYGLTSNTEIMNKIYEHKEPWTINSFADILSNFIFEDKEYIKNSKEYYIEERKYML
                     QELRNIRNIKVYDTDANFILIRAYKKTTKELKKDLLKQGNILVRDASNFIGLDDSFIR
                     VAIKSHEDNKILIENMKNLLGD"
     gene            17752..18639
                     /locus_tag="JAM15_10620"
     CDS             17752..18639
                     /locus_tag="JAM15_10620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HAT6798707.1"
                     /translation="MKSYGICPASCGEFVQGIIDDEEYLCSYAIDMYSEVYIEEKLVD
                     INLGRYKSRLAIEKVFEKFNLPKKYTKNISLNINSKIPVGKGMASSTADIGATIKATL
                     SLIDKDLSSEEISKLAAEIEPTDSIFIDKNSIFNPLNGTVIKYLGNLTNAKVIILEPN
                     KVLDTMKIRLRQDYNKLKVENKEVIKKSFALLEEGLKKNNLSLVGEACTLSSLANENI
                     EKKEYLNEIIKISKKYGAYGVNIAHSGTVVGILIDKSMNDKKMIDTLCESNINSVYNK
                     IYTQNIINGGIKGEIEWNT"
     gene            18627..19259
                     /locus_tag="JAM15_10625"
     CDS             18627..19259
                     /locus_tag="JAM15_10625"
                     /EC_number="5.4.99.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-8 methylmutase"
                     /protein_id="HAT6798708.1"
                     /translation="MEYIKNPMKIEEKSFELIQEIIDEIRPDYKFKNNIEEKIIKRAI
                     HTTADFDYLDILKISEEAVDSIIDALKNNASIYTDTNMALSGINKRKLESLGCKYKCL
                     VADDETVKLAKEKGITRSMAAVEIAAKEEGRKIFVLGNAPTALYKVMEMKSEGRLDLD
                     AVIGVPVGFVGAQESKDEVEKTDIPYIISKGRKGGSNLAAAIVNAILYTM"
     gene            19268..20494
                     /locus_tag="JAM15_10630"
     CDS             19268..20494
                     /locus_tag="JAM15_10630"
                     /EC_number="2.1.1.195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-5B (C(1))-methyltransferase"
                     /protein_id="HAT6798709.1"
                     /translation="MEEYVYIDGKKYRRGYTTGSCATGASKAAVYMLITKNRINTINI
                     DTPKGIPLLLKVDNINISDTFVECSIKKDGGDDIDATHTMDIYARAEIVAKNDKNKGY
                     LTLKDIDSLSTNSECKSELYKFIRVYGGTGIGVVTKKGLSVDVGKPAINPTPLKMINH
                     EIRKLIGDNFESILGNDKVLKITIFAPQGETVAKKTFNPRLGIVGGISIIGTTGIVEP
                     MSDEGWKKSLSIELQMKKEQGLDKIILVPGNHGEQFIREKLNLDIKYVVRVSNFIGYM
                     IKEAQRIGYKKILMAGHIGKFIKVSAGIFNTHSKVADARSEILVANLALMGARYEFLN
                     KINQCVTTEEAVELINNSEYREVYNILSNKCKERVKQYLNEDSDDIDVEVIIFSMDKS
                     LLGKSDNTDDLVEVFI"
     gene            20491..21099
                     /locus_tag="JAM15_10635"
     CDS             20491..21099
                     /locus_tag="JAM15_10635"
                     /EC_number="2.1.1.289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-7 (C(5))-methyltransferase"
                     /protein_id="HAT6798710.1"
                     /translation="MINIIGLGPGNLDYITKKGENLISTSDVLIGGKRNLESIKNFEG
                     EKIVLDSNLREIIEYINNNKEKQISIIASGDPLIYGIGRYLSKNIDNKMLNVVSGISS
                     LQYIFSKIYVDMNDVYITSSHGKIPDFDYILSHKKVCMVTDSKIGPKQISREIIDRNL
                     NKIIVVGENLSYDNEKITIAKPEEIIRMDNFDMNVVVILDEE"
     gene            21089..21664
                     /locus_tag="JAM15_10640"
     CDS             21089..21664
                     /locus_tag="JAM15_10640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating cobalt-precorrin-6B
                     (C(15))-methyltransferase"
                     /protein_id="HAT6798711.1"
                     /translation="MRNSEFITGKVPITKEEVRAISINKLNLVNAKNLIDIGAGTGSV
                     SVEAAYNYPNLKVISIEKNDDAIELIEKNIKKFNLKNIEVIKGYAPINLGLNVKVESI
                     FLGGTGNNLEEIIEWSKKNLVTGGRLVANFIIIDTFNQTLKLLKKHGFKEIDVCVLNV
                     SKLEKLGKGEYFKPLNPIYIISCEKGENDDE"
     gene            21657..22409
                     /locus_tag="JAM15_10645"
     CDS             21657..22409
                     /locus_tag="JAM15_10645"
                     /EC_number="2.1.1.271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-4 methyltransferase"
                     /protein_id="HAT6798712.1"
                     /translation="MNKVHFVGAGPGDKELITLKGYKLLSNADVVIYAGSLVNPELLE
                     YCKEDCQIHNSAHMDLQEIIDVMREGIENNKSVVRLQTGDFSIYGSIREQVEDLNKLN
                     IDYDCTPGVSSFLGAASSLGVEYTVPEISQSVIITRMEGRTPVPEKESIQSYAKHQTS
                     MVIFLSVQEIEKVVSKLLEGGYPKDTPIAVIYKATWADEKIVKGTLSDIAVKVKENNI
                     NKTALIMVGRFLGEEYNNSKLYDKDFKHEYRG"
     gene            22393..23514
                     /gene="cbiG"
                     /locus_tag="JAM15_10650"
     CDS             22393..23514
                     /gene="cbiG"
                     /locus_tag="JAM15_10650"
                     /EC_number="3.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin 5A hydrolase"
                     /protein_id="HAT6798713.1"
                     /translation="MNIEGNIAIICITENGKNLAVKINSLVNNCVIYQVKNKKSNLVV
                     EETCVHTVQKKLSDFVGEIFSKFDYIIFIMATGIVVRSIAPYIISKFSDPAILVMDEK
                     GKNVISLLSGHIGGANNLTQYISSLIDANPVITTATDINQKASLDMIAKKLNAHIDNF
                     RESVKEVNSMLVNNKCVGLYVDEGYQVDTRGFKLIESKDELRDSFSNTYIEKLVVVSN
                     KINCIEDIENLNLDNKFEHCYSTKKIIKVIPRDIVIGIGCRRNTDSELMYNLLEEFLN
                     KQNIDIRAINTVGSIELKKDEKAIIELSKILKVPFKTFSIDEISKVDNLFDKSDFVKK
                     NVGVYSVAEPIAYLLSKGNLLVEKHKYKGITFSVGRIKV"
     gene            23511..24236
                     /gene="cobJ"
                     /locus_tag="JAM15_10655"
     CDS             23511..24236
                     /gene="cobJ"
                     /locus_tag="JAM15_10655"
                     /EC_number="2.1.1.131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-3B C(17)-methyltransferase"
                     /protein_id="HAT6798714.1"
                     /translation="MIYVVGIGPGSKDTMTLEAIKAIEDSEAIVGYKTYIKLIEEFIQ
                     GKEIIQNGMRQEVDRCKQAVEEAKKGKKVAVVSSGDAGIYGMAGLILELISKEDEDIK
                     VKVIPGVTASIGAAAILGAPIMHDFCHISLSDLMTPWEVIEKRLRLAAEADFVICLYN
                     PRSKGRSEHLSKAFKIMGEFKGGDTPVGVVKDVGREKEEKFVCTFENMDFEKVDMTTM
                     VIIGNKSTYINGELMITPRGYTV"
     gene            24233..24985
                     /gene="cobK"
                     /locus_tag="JAM15_10660"
     CDS             24233..24985
                     /gene="cobK"
                     /locus_tag="JAM15_10660"
                     /EC_number="1.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-6A reductase"
                     /protein_id="HAT6798715.1"
                     /translation="MILILGGTSDSLSICDKINELKNQPYILSVTTDYGRELAQQHAE
                     NVILGKLGKEDMLKFIKDNNIVKIIDATHPYAVEVSKTAITCAKLLNIDYIRFERKSL
                     IEEIDYDNKFIVDTIEEACEIANKIGTNIFIGTGSKNLNRFIEEISDKNLVVRVLPTS
                     EVILSCEKLGLSADNIVAMKGPFSQYINEETYKHYNIDLVITKESGIAGGFLEKVNAC
                     KTFNIPVIIIKRESINYENVFNDINKIKDILV"
     gene            25004..26494
                     /locus_tag="JAM15_10665"
     CDS             25004..26494
                     /locus_tag="JAM15_10665"
                     /EC_number="2.1.1.151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-factor II C(20)-methyltransferase"
                     /protein_id="HAT6798716.1"
                     /translation="MKKALLVVSFGTSYHETREKTIDICEDKIKNSLKSHDFFRAYTS
                     NMIINKIKKRDGIEIDNPIQALDKIYEQGYDEVIIQTLHIICGEEFNKLKEQVDGYSS
                     KFKKIVLGRPLLTHIEDYQEAVEAIKHQIPHMESNEAVVFMGHGTLHESHSAYPALEY
                     MLRDNGINAYVGTVEGYPEIEHVIRRLKEGNIKTVNLMPFMLVAGDHAINDMAGDEED
                     SWKTILEEDGFDVRVHLKGLGENSYIQDKFVRHAVKCAENAKFYGIGAGPGDGSLLTI
                     KAVNTLKKLDILYTPESKKGGDSLALSIVSEYLPESVEIKSRHFPMSFDGNEKSLAWD
                     NVAQEIISDVNDGKNVGFVTLGDPMIYSTYVYIMKRILGEVEVETIPGISSFSNIASN
                     QNFPLVMDKEALVVIPCTMEDDKIEYALQNYNSIVLMKVYKNFKEIIKKLEKYDLIEH
                     AILVSNSSQESENVFTDLKEAHLEDKISYFSTILVNKDNKIGESNI"
     gene            26507..27412
                     /gene="hemC"
                     /locus_tag="JAM15_10670"
     CDS             26507..27412
                     /gene="hemC"
                     /locus_tag="JAM15_10670"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HAT6798717.1"
                     /translation="MNIVVGTRGSNLALIQTEWVINELKKKYPEISFEIKIIKTKGDL
                     IQNVSLDKIGDKGLFVKEIEQQLLDGKIDIAVHSMKDMPSYLADGLKFAHTPKREDPR
                     DVLILREGYKNLDDLPHGAVIGTGSKRRKFQLLKQRPDLNIVQVRGNVETRIRKIKDE
                     NMHGIVLAASGIIRANLQDKISSYLPVDVVIPAPAQGALAIEIRSNDSTIEGIVNSLK
                     DENTEIQILAERGFLDGVNGSCHIPMAAYCEIIQDKIHLTGLYGDSEGKKVVIKSIDG
                     DISSPRELGLKLAKLVLKEYENYEG"
     gene            27402..28901
                     /gene="cobA"
                     /locus_tag="JAM15_10675"
     CDS             27402..28901
                     /gene="cobA"
                     /locus_tag="JAM15_10675"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HAT6798718.1"
                     /translation="MKGKVYLVGAGPGDYKLMTLKGLECIRKSDVIVYDRLANSSYLR
                     EAKPDCELIYVGKASSNHILPQEDINRIIAEKAKEGKIVTRLKGGDPYVFGRGGEEAE
                     TLVDEDIEFEVVPGITSAIGGLCYAGIPITHRDHASSFHVITGHLKGDDSGELNWNAL
                     ANNKGTLVFLMGISNLEKISENLMKEGKDKDTPVALISWATRYNQRVVTSTLENVYET
                     AIKEEVKPPTLIVVGSVVGLREKLNFFESKPLFGKSIAVTRSRNQNSVLVEKIMDLGG
                     NPIEIPTIKVEKIQNNINLENEIKNINKYNYLILTSKNAVEIFFEKIYEMNFDLRILS
                     NLKVCAIGSATSNELKKRGIIADIVPKKFVAESLYEELAPILNDNDNILIPRAENARD
                     YLVDKLKAICEVTEVHIYRTVIDEDKKGEILDILNSNDIDYITFTSSSTVNNLVEIIG
                     KENIKILEKIKTLSIGPITTETINSLGIKLYKESATSTIDSLVDLIIKN"
     gene            28918..29883
                     /gene="hemB"
                     /locus_tag="JAM15_10680"
     CDS             28918..29883
                     /gene="hemB"
                     /locus_tag="JAM15_10680"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006783548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HAT6798719.1"
                     /translation="MLRRPRRLRASKAIRNLVRETKVNVEDLIYPLFVVEGENIKEEI
                     KSLPDVYHLSIDMLEDEIKEISELGIEHIMLFGVPDEKDECASQAFNDNGIVQKAIRK
                     VKEINSDINVITDVCMCQYTSHGHCGILTDTGYVDNDKSLEYLAKISVSHAKAGADMV
                     APSDMMDGRIQAIREALDENGLENVGIMAYSVKYASNYYGPFREAAHSAPSFGDRKTY
                     QMDPANSNEAIIETELDILEGADILMVKPALSYLDIIRRVKDNFDLPLAAYNVSGEYS
                     MLKFAVKEGLLNEDVILESITSIKRAGADIIITYFAKDIAKLLKK"
     gene            30036..30614
                     /locus_tag="JAM15_10685"
     CDS             30036..30614
                     /locus_tag="JAM15_10685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional precorrin-2
                     dehydrogenase/sirohydrochlorin ferrochelatase"
                     /protein_id="HAT6798720.1"
                     /translation="MLYPINLKLDELDVVIIGGGEVAYRKCKNFLEFNKNVTIVSKQI
                     LNKFYDLKGNIKIIKDDYKEIYIKDASVIIAATNNRELNMEIGLYCRAKNKLVNVVDN
                     IEISNFTVPSYIKRGDLLISVSTGGKSPSLSSKIKKEIEERYTEDYEEYLNVLGDIRK
                     KVIKKYEDKSKRKDVLNMLVTLDLEELKKFDI"
BASE COUNT        12411 a         3059 c         5665 g         9516 t
ORIGIN      
        1 tatattaaat tttggaatca aaatatacta ggatataaaa ttcttaaata aaaagaaaag
       61 gttgttttta taaaaaatat tttttatacc actttaaaaa acacaataat aacactgagg
      121 gaggtgggga tatgagagaa cgcattattc ttgaaacatt aaaaaatagt agtggttatc
      181 taaacataga ttattttgca gataagttgg gggtatctac tcgaactatc agaaatgaaa
      241 taaaaaagat agaaactata aaagaatgta atggttttaa attagaatat aagtctaaat
      301 taggatatat tctaaatatt aaagaccaag ataaattcga gcattatcta agaaacttac
      361 cctcagattt agttgaaaat ccagaacaac ggttggagtc tataatagta gagcttttag
      421 taaatgaagg ttataaaact atagaacagt taagtaaaaa atttctagta agttcatccc
      481 aaataaaaaa tgatttaaaa aagatagatg aaaagataaa ggatacagaa ttaaaactag
      541 agcgaaaggc tcattatgga attaaaatag aaggttctat taaagaaatt caaagtatat
      601 tggtggatag ttattttaga gggaatagaa atataacaga gtacaggaat aagtttatag
      661 ataatttaaa attagctaat attagaagta caataaaaaa tgtacttaat gaacatgatt
      721 tagaagcaaa tttaacagaa cttgaggaaa tattagcaca aattattata ttgtatataa
      781 gagttagtat gagagtagtg ggaaatgcta gcaatttaaa attatataca gaagatttaa
      841 ttatagataa attattagat aaaattttta gagataaaaa atataacctt aattatgatg
      901 aaaagtatta tttaaaggag cttataaaac taaagactaa agataagaaa gccactataa
      961 agaatattga taagaataaa cttcaagata ttatgttcga attttttaga gagatagata
     1021 aaaaatataa ctctaatttt ttagaagata aagagttttt taacttattt tacttacata
     1081 ttgcatgttt aatagaacgt ataaagaaga accacaagat aataaatcct ttttcagtta
     1141 aaataagtca acagtatcca actgttttta atttatctat tcaattttca aaaatcatag
     1201 aaaatgagta tcatataaaa ataagtcaag atgaaatagg gtttatagct actcacattg
     1261 ctgttccttt tgaaaagaga gaagaagcta attttaataa aaaatataaa atagcaataa
     1321 tatgctcttc tggtggaggt agtgcatttt tgataaattt aagacttaaa gaaatttttc
     1381 caaatgctga gataagaaat ttttcattac tagaagaaaa agctgtaata gaatttgcac
     1441 cagatttgat tttttcaata acaaatcttt tatttgaaat aaatgctcca gttatactta
     1501 taaatgaaat tttagacgag ttggattatt tagatattaa agaaagtgtt agatttgcag
     1561 accatatagg aaatatatca agcccaaaac aatatatatt aggtctattt gataagaatc
     1621 actttaggtg tataaaagat aaagctaagt ataaggatat ccttgatagt atgtcaaaat
     1681 gtatagttga cgagggagct tgttctccaa cctatcccaa agatgtatgg gaaagagaaa
     1741 gctatttgag tactatttat acaaatgggg tggctatacc tcatccaatc gagatgacag
     1801 gaaacaaaaa tataatatca gtagctttga tacaaactga tattatttat gaaaataggg
     1861 tgcccaaaat tattttcatg atttcattaa taaagggaaa tttagaactt cataagcaaa
     1921 tatctaaata tttaagtaag attatggtaa ataaggatat ggtagacatg ctaaataagt
     1981 cacaatctta tgaagagttt atgtataagt taaaaatcta tctgggaggt tagacatgaa
     2041 tatagagttt tttaagaggt tgtcagaagc agatggtata gcatctaatg aagaagaggt
     2101 tagacatgtt ttattggaag aactaaaagt ttatagtgat aaaattatct gtgatgggct
     2161 agggagtatc atcttttcta aaataaaaga tgagagtgca ccaaacgtaa tgatttgtgc
     2221 tcatatggat gaagttggat ttatggtgag aagtatagac aaacttggta tgattcactt
     2281 aataacaata ggaggagtaa aacctcttgc acagtttgta caaaaagtta gaattacaac
     2341 aaaagaagga aagaaaatcc ctgctgtcat aaatgctaca tataataatg gtaaggctga
     2401 aaatatatat gcagatattg gagcatatac agaagaagat gtatataacc tagggattaa
     2461 tgttggggat atggtaacat atacaacaag ttttgaggaa tttactttac cagaccgatt
     2521 agtgggaaag gcttttgatg ataggatagg atgttttgtg atgggagaag ttttaaaaga
     2581 acttaggaaa gaaaatctaa attgtaatat tcactttgcg gctacaagta gtgaagaggt
     2641 tggaataagg ggagcaaaga catcaacaca gttaataaat ccagatatag tatttgtaat
     2701 agatgtagca tgtgctaaaa atgagtttgt gagagactat acaaatcaga aacaaattga
     2761 taaaggtgta atgctaatgc atagagatag gactctagtc cctagtagaa aaatgataga
     2821 ttatgtaatg gaaattgctg ataaaaataa tataccactt caacatgata tgtttgaatc
     2881 aggtgggact gatggaggag aagcacatct cgtaaatgaa gggaaacctt gtgtagtaac
     2941 ttgtgtacca gttagatatg gtcattgtgc attttcaata gtaagtaata aagatttaga
     3001 gaacattata agattgtata cacagttaat tttaaatttt gatgaagaac aatataaaca
     3061 tataagaaat tttatctaaa ggagaataag aaaatgtcaa cagaagtaca aataatggag
     3121 cttatatcaa ctgcaggaga gagtaaatcg aaagcttttg aggctttaaa aaaagtaaag
     3181 tcaaaagatt ttaaaggagc aaaattgtta atagaggagg ctcgtaaaat agatattgag
     3241 gctcacagaa tacagacaga attaataact caagatttaa atgaagatgt tgaaagccca
     3301 acaatgagtc ttttaatggt acatgctcaa gaccactata tgacttctca gctagcaaaa
     3361 gacttgatag aggctttgat atattgtctc gataagtaat tgtaatgtag aaatagatta
     3421 tttatgtaaa aattctttta aaagtttaga tgcttttaag agataataaa aatacaaact
     3481 ttaggaggaa ttattatgaa aatattatta tgttgtgcag gtggattttc tactaatatg
     3541 ttaatgcaaa atatgaaaaa ggtggtaaaa gagagtgcta aactcaatga aaaagatttt
     3601 gagtttacag ctataccagc agattcaata gaaagtgaag ttgatgattg ggatatagta
     3661 cttataggtc ctcaaatagc tcataaaata gacttcttaa aaggaatatt agagccaaaa
     3721 aataagcctt ttgcagtaat agataaagat gtatatggaa aaatggatgg agctacagtt
     3781 atgaagttgg cattaataac ttataagaaa catcaattag ctcaaggata ataaaaataa
     3841 tgagggaaaa gggagattag atatgttttc aaaatttgaa gcatttatga atagagtatt
     3901 tatgccttta gctcataagg ttgacaatca acgtcacctt ggttctataa aggctggtat
     3961 ggttgctatg acaccattca caatattagg aagtatattt gcaatacttc cagcacttcc
     4021 aaatatgctt ggagaaaata atccaataag caaattcata cttaacaatt cagcaatatt
     4081 ggatttacca gtaagtcttt ccataggttt aataggatta tatgcttgta tgtgtattgc
     4141 ttttaatctg gggaactact ataaattata tataccaggt tgtgttgcac tatcaacttt
     4201 ttctttttta ttcctagtag cctcatttac accagatgga gctttagaaa taggaaattt
     4261 aggagctaaa gggctattta caggtatgat agcagggctt ggttctgtgg agttatataa
     4321 tttttgtaat aagaagaata tcacaataaa aatgccagaa aatgtacctg attttgtatc
     4381 taggtctttt gaattaatac ctactactat aatagtttgt ggaactttta tagttgctcg
     4441 ttttatttca ttaaaagtat ttggagaatt acctccacag atacttactc aatttttatc
     4501 tccattagta ggaagtatgg ataacccatg gtcagttctt gcacttaact ttgctatatg
     4561 tactatattc ttttttggaa tacattcatc agtatttagt cctataacta gacctataat
     4621 gattacattt atagctgaaa acatagcagc tatgcaagct ggagaaacaa tacctcattt
     4681 ctttacagca ggagcttcaa gtgcattctt tggatttaca ggatgtggaa ttagtatagg
     4741 ttgtgtaatt gcatgtatgt tatcaaaaaa tgcttcctat aagaagattg gacgtgtatc
     4801 attattccct gcattatttg ggataaatga accaatatta tttggagcac cgataatatt
     4861 aaatccaata atgtttatac cacatgtatt tggtggagct ataataggta cactaccaat
     4921 gttttttatg cactggggat ggttagcaaa gccagtattt gaccctccat atgtaggggt
     4981 attcttagaa ggatttttaa ctaatggaga ttggcattct atattagcaa atgcattgca
     5041 attagtatta gcagttttat tatattggcc attctttaaa ataatggaac gtcaacaaaa
     5101 taataaaaaa caaaaagaag aaactaagaa tatattctct aaagaagaag aagacttatt
     5161 ggatgattta ggattggatt tctaatattt tgttatgaat aatacaatag agagattagt
     5221 atccttaatc tataaaagag gtgttgacgc tcttttgatt aaagcaaaaa atactaaaag
     5281 atatatagga gctttatcag gtagtggtgt atatgtgctt gttactaagg ataaaaatta
     5341 tcaaattcta gatggcagat atattgatga agcagataaa aaaacgactg gtttcataaa
     5401 aaggattgta tctcaaggtt cttatatacc aactataatt gagttattaa aagaattaaa
     5461 tataaaaaag ttagcaatag aaaaccaagc tatgagtata caagagtatc tttcactaaa
     5521 aaatgaaggt tttgaaatca atttaataac aaatgaatta tggaagctaa gggctataaa
     5581 atctaaagaa gaaattgaac ttattaaaaa ggcttgtgag attacagatg aagtatttga
     5641 tgaggttatt tctgaaatta aaaaagatat gactgagcta gaagtatcag ctctaattca
     5701 gtatcatgca ttaaaaaaag gtgcaagtgg aatgtctttt gaaacaatag tggtatcagg
     5761 agaaagaggt gcaatgccac atggaagacc tacaaacaaa aaattgaaag tgaatgaagc
     5821 tataacaata gattttggtg ttgtttatca agggtatcaa tcagacatga ctcgtacaat
     5881 atctataggt aaacctccta aaattattaa agagatatat gatgtagtat tggaagcaca
     5941 attatctgca atagagtcaa taaaggaagg aactagggca agtgatgttg acaaagtggc
     6001 tagaaaaatt atagataaac atggatttgg cgaatatttt aatcatggac tgggtcatgg
     6061 tataggtctt ggagatggtg aagttcccac tttaaatcca aatagtgaag atatattagt
     6121 ggaaggaatg gtaatgtctt gtgagccagg tatttatatt ccaaatgtag ggggagttag
     6181 aatagaagat gatattgtta taatagatgg aaaaggtgtt ccactcaata agacatccaa
     6241 agagtttata atattaggag agtaaaatta tgaaatataa ttttaataaa gtattaaatc
     6301 gtaaagaagg aaattgtaga aaatggagca accatgtgat taaagaaaaa ttcggcttaa
     6361 atgaagatgc aattcctatg gatttagctg atatcgattt tgagtgtgct cctgctataa
     6421 aagaatctat cttaaaaaga gcatcagtag gagattatag ttatactttt ataggagatg
     6481 acttctatga tgctattata aattggaata aaagaagatt tgatgtatat atagaaaagg
     6541 attggataaa attaactttt ggtactgttt caacccttca ttatatagtt caagcatata
     6601 ctaaagaagg agagggtgta ttgataaata cacctgctta tgaccctttt gcagaggctg
     6661 tagcaaataa taatagaaag ttgtgttgta gctcattaaa attagataac aatagatatt
     6721 atttagattt agaggatatg gaaaatcaaa tgaaatacga gaatataaga ttacttatat
     6781 tctgtagtcc acaaaatcca tcaggtcgta tatggacaaa agaagaacta tatcaagtgt
     6841 cagagttatg tttaaagtat aatgtaattt tggtaagtga tgaaattcat agagatataa
     6901 tatttaaaga ttatagattt gtatctttgt ggaatgctca tccagaaatt tataaaaata
     6961 gtataatctg cgtatctcct aataaaggct tcaacttagg tggattaaaa acatcatatg
     7021 tattaataag agatgtaaaa attagggaga ctttattaga aaggctaaaa agtaattcaa
     7081 taacttctcc aaatgtattt gcaataccag caatagttgc agcatacaat gaaagcgaag
     7141 aatggctaga tgctatgact agttatgtag gggagaattt tgaaatagtt tatgatttct
     7201 ttgaaactaa tataccaaaa gccaaagtga tgaagtcaga ctcttctttt ttagcctgga
     7261 tagatgtaag agaagtattt agaaatgaag aagaatctaa agaatttttt agacatgcaa
     7321 acttaactat ggtagttgga agttattttg tgaaagatgg agatggattt attcgtatta
     7381 atgtggggtg tcctagagaa acattaaatg aggctctaaa tagaatcaaa aaaacgtata
     7441 taagtatgta ttgttaaatc ataaaaaaag tatctatggt ttatataaaa acacattatt
     7501 tagttatcaa atattactgg aattttgtat tccagtaata ttttttgatt aaggaatatt
     7561 attgaggaat attaaataat attatttcat acccttatat taacttatat aaaaatattt
     7621 tattattttg ggaacgggtt agctaacctt tatctagtgt atatttatat tgtaagaagc
     7681 agtaaaaact tttcctttac taagtttatt aataaacttc ttatctttat aaattttgtt
     7741 agaatttata ctatcagcaa gaccatacca aggttctata cataaaaaag gagcagtaga
     7801 attagtttca ctataataag gagtccaaat accaactaga gggaaatctt ccatagatat
     7861 agttacatat ttactaccat cattattaca tatagacact tcatctatgt tggtgtatat
     7921 caaagcatca ttcttgaata cttctggatt taaatgtaag ttttttaatt ttccaatagg
     7981 tattatatca tctgtaaaag aaccatttaa attgattttt tctacatcat ttttactttt
     8041 aaactcaagg tagtgtttgg aaaaatcatt ttgttcgtaa aaaggaaggt tgaatgcagg
     8101 atgtccacct atagaaaaga atatatcttt agagtcagta ttttttacaa tccattctac
     8161 ctcaatacta ttatcattta atgtatagtt tatgattagc tcaaaagaat atggatactt
     8221 ctttaaagtg gattcattat ctgttaattt ataagataca aatgtatctc ctttatctac
     8281 aatctcaaag tccatatctc tagcaaaccc atgttgagtc atgctatata aattttcttc
     8341 tattattgtt tcattatcaa aaagtttacc tactataggg aacaatatag gtgattgtct
     8401 accccaatat tttttattac catcccaaag aatgtttttg tcgtattttt tagaaaatat
     8461 tttagttagt tcagcaccaa aactgcttga ttcgataatt aaattttcat tttgtaatat
     8521 attcatttaa aatctccttt attatatttt atgagtatat tatactataa agtataaaga
     8581 ttattaaatt ttatttgata ttatatttga aaggtagatt ttagtatatt ttgaaaattt
     8641 tgttttgaaa atttgggatt atttaagaaa ttttgtatta taaatagaag gaaatagata
     8701 aattgtatag aataaaatat attaagataa gttaataatg ttaaatggga agtgagttta
     8761 tggaaaaacc aaatacaaaa gttgttaact ttcaagagta taaagacaga aaaaaccaaa
     8821 gagaagtaaa tagagacgaa cttttaaagc ttataaaaaa aattgtgact tcaaaatagg
     8881 gagttgttaa actccctatt ttaatgggtt tcataataat taagacattc tgagtccatc
     8941 tatataatct ttgaattgtg agaaatctga ttcactactt aattctatgg tttctgaacc
     9001 ttccgtataa aaattcttaa gatagatagt ataattatta tcaacacaat catgataaat
     9061 acatctatat ccatcttcat acaaactttt taacttagaa aaatcatcca caatatcatc
     9121 tccttaaagt tcttttaaat atatttttac aaaaagcatc taattgtatg caaattgaca
     9181 atgtaaaata aaggaaatga acataaaatg tagaataatt tttatatgta tgtaaaaata
     9241 aaaagaaaaa gttgaaattt ttagaaaata agagtatttt ttatctaaaa agagagttta
     9301 aaaaataaaa aaatgttggg aggataaaaa atgagtttat tagaaagtat atcaaaaaac
     9361 atatattccc tagataactc ttctattgaa aaaacaaagc agagattgga taggcttata
     9421 catccaactg gaagcttagg aaagatagaa gatatttgca tgcaattagc aggaatattt
     9481 ggcaatgaaa attttgacac aagtaaaaag gttataattg cttttgcggg agaccatggt
     9541 gtatatgaag aaggcgtagc acctgaccct caaaatataa caaaattaca gtttccaaat
     9601 ttttcgaaag gtctatgtgg agttggagta ataagtaaat ttgtaggggc agatgttgta
     9661 gctgtagatg taggaataaa ctgtgatgaa aaactggatg gggtattaga ctacaagata
     9721 agaaaaggga catcaaatat ggcaaaaggc tcagctatga gtaaacaaga agccattaga
     9781 tgtttagaga taggtattga aatagcagag cagtgtatag aaaaagatta taaggttatt
     9841 ggtattgggg agatgggtat agcaaatact actccaagta cagcaataat atctgtaatt
     9901 tcagggtgtg acccgttaga agttactggt ataggtgcag gtcttaagaa agaaagacta
     9961 aagcataagg ctgaagtaat tagaaaggct attgaaatta ataatccaaa tccaactgat
    10021 ggagtagata ttttatctaa agtaggagga tttgaaatag gctcaatggc aggtgttata
    10081 ttaggttgta gtgctaatag gattccagta gtaattgatg ggtttatttc ttatgcagca
    10141 gcattaattg catataagat aaatccaaaa actagagaat atatgatagc atctcattta
    10201 tcagcagaat caggaactaa aagagcatta gacatattaa aattagaccc tctattaaat
    10261 atggatatga gattaggtga gggaagtgga gctgctttag catttgatat aatagaagct
    10321 tcaaactata cttacaaaaa tatggcaact tttgatgaaa ttgacatggg aagataaata
    10381 taaaaattta atatgtagga gtgttttgat gagtaaaatt attctagtaa caggaggagc
    10441 taggtcaggg aagagtaact ttgcagaaaa actatgtttt gacagaaata ataatacagc
    10501 ttatatagca acctctattc catttgatga tgaaatgaaa gatagagtaa aaaaacatca
    10561 agagaataga cctagaaact ggaatactta tgaaatatat gaagatatat attccataat
    10621 taaggagata tataaagaac atgaaactgt tatactagat tgtgtaacat tattagtaaa
    10681 taatctaatg tttgaacaca atctaaatat agaagaatct agtcaagaag aaataaacaa
    10741 attagaacaa tacataaaag aacaagttgt caaacttatt gaagaaatag aaaaaacaaa
    10801 tctatacttt gtatttgtaa cgaatgagtt aggtatggga attgttcctg ggaataaact
    10861 tagtagaatt tatgctgata ttgtaggtcg tataaatcaa tatatagctt cgaaaagtaa
    10921 tgaagtttat tttgtagtta gtggcatagc tatgaagata aaggagtagt atgcaattat
    10981 gaaaagattt attttaatac tacagttttt gacaaggata cctataaaat taaatgtagg
    11041 atttgatgat gaattttata agtcaatagt atattttcca cttgtaggtt ttgtcatagg
    11101 gatattatcc tatttaatag gatggatttc tatgctttta tttgaaccat ttatagcttc
    11161 tataataata actctagctg gtgtcttaat tactggagga cttcatatag atggattagg
    11221 agatacattt gatgcaatat atagttatag ggataaagaa aaaatgcttg aaataatgaa
    11281 agattcaaga ttaggtacaa attcacttct agcaattatg tttgtacttt tattaaaggt
    11341 tggattcgtt tatgatataa taagtaataa ttcattgtgg attataattt ttatgccaat
    11401 gattgcaagg ttaggagtaa tgttattgac atataaaacc gtgacaccaa gagaaaaagg
    11461 aatgggaaat ttatttatag gaaaattaac tacaagtatg ttaataactg ctataatata
    11521 cacattattg atagttgctc ttattactaa atttatattt ttattaccta atatagtgtt
    11581 gattaaagta ttaggttcga ttatagtggt ttttgtattt ataatattat tcaaaaaaca
    11641 tatttataaa aaaattgacg gagtaacagg agatatatta ggctgtggaa tagaactttc
    11701 agagcttgta tatttaattt acatatattt gttaattttt atgttttttt aaagtaaaaa
    11761 gtggtgataa tatgataaga ttaatattaa taagacatgc actgacaaat gataataaaa
    11821 aaggaagatt atcaggccat ataaatagtt gtattagtga agagggcaaa ctacaaataa
    11881 ataaaattac cagatatctg agtaatgaaa acatagataa ggtttataca acaccatcta
    11941 cacgtactaa agatacagta gaaaaaatat caaaattgaa attattagaa atagaagaaa
    12001 aagaagcttt aagagaaatt agttttggag actttgaagg aagaactttt gaagaaatta
    12061 aaatcaaata tccaaatgag tttgaaaaaa tgataaaaga aggtaacaac tatagatatc
    12121 caaatggaga aagtttgata gactcttata aaagagtggc aaaagaaatt gataatataa
    12181 ttttagaaaa tgatagtaat ttagatacaa agacaatact tatatgttct catgcaggaa
    12241 caataagaaa tataataaca catttgattt ctggtagtta taagtatcac tggaacttta
    12301 aaattgataa tgcatctatt acagttttag aaattgatgg tggatttgct gtaatagata
    12361 aaatgaattt tacagacttc atataattta atcaaaacca aacattacaa tctgtgtttg
    12421 taatatatct gtaaaattag caatgaaaat agaatattag attaaaatta ggttcttaat
    12481 tagatgttaa aagggaaaaa ggttagatgc ctttgcagcc cccgctactg tgaaaccaac
    12541 gaaactataa ataccactgt cagtttgatg ggaaggttat agaagtagga tgaagttaag
    12601 ccaggatacc tgcctaattt aatttaaaac aagaggtctt cggggtgaaa gatttttaat
    12661 taatatatat aaaagtccta tctttagaag tattaggact ttttttaatt tgttttttag
    12721 taaattttaa caaggaggga tggaaagtgg ggaaaaaaat aatgctacaa ggaacagctt
    12781 caaatgtagg taaaagtgtc ttagtagcag gtttgtgtag aatatttaag caagatggtt
    12841 atactgttgc tccttttaag tcacaaaata tggctttaaa ttcttttata actaaagaag
    12901 gattagaaat gggaagagca caagtatttc aagcagaggc tgcgaaaata gagccaatag
    12961 ctgatatgaa tccagtttta ttaaaacctt ctggaaataa taaaagtcaa gttattgtaa
    13021 gaggtaaagt tgtaggagaa atgccttctt ctaagtatca tgattataaa ttggagttag
    13081 taggtgtgtt gaaggaaaca tttaatagct taaattcaag gtatgatatt gtagttatgg
    13141 aaggggcagg aagtaatgca gagataaact taaaagatag agatatctct aatatgggta
    13201 tggcagaaat agctgatgca cctgtaataa tagtcggaga tattgataga ggaggcgtat
    13261 ttgcctcatt agcaggaaca atgcttttat taaatgaaga tgagaaaaga agagtaaaag
    13321 gtgtaataat caataaattc agaggaaaaa aagagctttt acaagatggt gtaaagatgc
    13381 tagaagacat cataaaagta cctgttatag gagtagtacc ttatacagat ataaaaatag
    13441 aagatgaaga cagtgtaact acgagattta agaaaaaaat gaataaaagt gatatacaca
    13501 tagaaataat tagaacccca catatgtcaa attttacaga ttttaatata tttgagacac
    13561 aagaagatgt aagtattaga tatgtagact atggagaatc tttaggaaat ccagatatat
    13621 taataatacc tggaactaaa agtactatag acgatttaac atatataaga aaaagtggtc
    13681 ttgaatcgca aatcaaaaat ttacatagtc aaggtaaatt gatatttggg atatgtggtg
    13741 gataccaaat gttaggtaaa aaattaaaag acccttatca tgttgaaagt gaaattgaag
    13801 aagttgatgg aataggtctt ttagatacag aaacaacgtt tgagaaagaa aagactacaa
    13861 cacaagtaga ggctactatt gttgaatgta tcagtgaata catgaataac cttaagggaa
    13921 aaaaagtaaa aggttatgaa attcatatgg gtattacaaa gcgaggtaat gatgtaagaa
    13981 gtttagattt agtaactaaa aaacttgata aagaagtgaa ttatactgaa ggaagtgtaa
    14041 ataaagaggg gaatgtaatt gggacttatc ttcatggaat atttgatgaa ataagcttta
    14101 caagagcaat tttaaacaat ataagaaaga aaaaaggttt aggagaatta gaaagcaaag
    14161 taaactcttt taatgaattt aaggataaag agtatgataa gttggctgat tttttaagag
    14221 aacatttaga tatagagaaa atatatgaga ttatgaaata atgatgacct ttatttataa
    14281 tttaggtagg aggtgtatta tgaaaaaaat tttaattgct ggtactaata gtggagtagg
    14341 taaaacaaca atatcattag gaataatgca agctttggtt aagagaaata tgaaagtaca
    14401 gccatataaa gtagggccag actatataga cccttcatat cacactttta taactggaag
    14461 acattctaga aatttagatt cttatatgtt agatgatgaa aaaataaagt atatagtaaa
    14521 taagtcctca aaagatgcag atatttcagt aatagaaggt gttatgggct tatatgatgg
    14581 ttttggaata gatttagata attgtacaag ttcacatact tcaaaggtat taaagtcacc
    14641 tgttatatta gttataaatg gtaaatctat ggcagcatct agtgctgcta tggtacttgg
    14701 atataaggaa ttagataaag atgtaaatat aaagggtgtt atagtaaata atgtaaagac
    14761 taatagccat tatcaaataa ttaagagttc tatagaaaaa tattgtaatg ttgaagtatt
    14821 ggggtatttt cctccaaata acaaattctc tttagaatct cgacatctag gattagttcc
    14881 tagtgtagaa atgaaatcac taagggaaaa attttatacc ttagcagatg aaattgaaca
    14941 ctatatagat attgacagaa taattgaaat atcagaaagc gatgaatttg agagtgattt
    15001 tgattttcaa actttgatag aaaataataa aataaaagaa catgttaata ataaatcaat
    15061 agctatagca tatgataaag cattcaattt ttattataga gaaaatatag agcttttaga
    15121 ggaacttggt ttagaaataa actattttag ccctcttgaa gatgcatcag tgccaaatgc
    15181 agattatatt tatattggag gaggttttcc agaaatattt ggaaaagaat tagaagcaaa
    15241 tgagtcaatg agaacttcca tattagaagc acataacaat aatataccta tttatgcaga
    15301 atgtggagga ctgatgtacc taggtgagaa actattgaat caagaagaac aagaatttaa
    15361 tatggttgga atatttagtg gaattagtaa gatgacatct tctttaaaga gatttgggta
    15421 ctgtattggt gtagccaagg aaaatactct tttatctaaa aaaggggaat ctattaaagg
    15481 gcatgagttt catcattcaa tatttgaaag tgatgaaaaa tgtgtatatt caatgagaaa
    15541 agaaagagat ggaaatatag tagaagagtg ggatggtggt tatagtaaag gaaacacttt
    15601 ggctacatat cttcatactc atttttataa taacttaaat tgtatagaaa attttttgaa
    15661 aaaaggaaat gaataaatga gtattttatc tatttatata ggatatgtga cagacttaat
    15721 tgtaggagac ccatattctt ttcctcatcc agtgagattt attggtaaac ttataaattt
    15781 tactcaaggt ataataagaa aggtctctaa aaatgatagg cagttaaaat ttgggggatt
    15841 tatattatgg tttataaccg ttggaataac atatttaaca acttatgcta tagtgaagct
    15901 atttagtttt aatatattat tgagtattgt agtgaatagt tttataattt atacaacact
    15961 agccacaaaa tgtttaaaag acgaagcatt aaaaatttat aatgtattaa aaactgaaga
    16021 tatagaaaaa tctaggattc agctatctta tatagtaggt agggatacta ctaatttaag
    16081 tgaacctgaa ataataagag caactgtaga aactgttgca gaaaatactg tagatggtat
    16141 aattgcgcct atgttttatg catttattgg aggagcacca cttgctatgg cctataaagc
    16201 tataaataca ttagactcaa cagttggata taaaaataaa aagtataaag atattggttt
    16261 tgcatctgct aagattgatg atatagccaa ttatatacca gctagaatat ctgtcattct
    16321 tatgacaatt ggaagtttct ttttaaatta taactataga aactgtttta aaatctctat
    16381 tagagataga aagaatcata aaagtccaaa ttgtgctttt tcagaaggcg cagtatctgg
    16441 tgctctagga atacaactag gaggtaccaa cgtttatttt ggggaaaaag tatataagcc
    16501 aacaataggg gataagctta gggagataga taaagaagat ataattaaaa ctaataaaat
    16561 tatgtatgta tcttcatttg tatctatgtt ggtatttaca ctaatacatg tgttatgtag
    16621 gatgatttta attaacttaa ttatataaat tattgtttgc taacttaagg gggacataga
    16681 tgaaggattt agggcatggt gccaatgtag gtgaaatggc aagattatat gggaaaaacc
    16741 caaaagaaat aattgatttt agttcaaaca taaatccaaa tgtattacca aatttagaga
    16801 gatacatttt aaaaggatta gaagagtgta ggaattatcc agatataaat tatacaaact
    16861 tgagagaaaa tatatcaaaa tatataggta taaatccaga ctttataata cctggaaatg
    16921 gtgcaacaga agtgatttat ttgcttatga agagtgttaa aaaaaaattg gctataataa
    16981 atccgacttt ttcagagtat agaagaagtg ctgagttaaa taatttagat attatagatt
    17041 tagagctaga tttagaaaat aactttaaac ttaatataga tataataaaa gaaaatataa
    17101 aaagatttga tagtttattt atatgtaatc ctaataatcc tagtggtaat gtccaagatt
    17161 taaaggaact tgttcattta ctaggtaaac ataataaggt actaataatt gatgaaactt
    17221 tcatggaatt tgttgaagat gaaagtaaat acagtttggt taaatatata gaatcaaata
    17281 aaaatatatt tataattaaa gctgtgacta agttttttgg tatgcctggt ttaaggctag
    17341 gatatggtct tacaagcaac actgaaatta tgaacaaaat ttatgaacac aaagagccat
    17401 ggactattaa ttcttttgca gatatactat ccaattttat ttttgaagat aaagagtata
    17461 ttaaaaatag taaagaatat tacatagaag aaagaaaata tatgttacaa gagttgagaa
    17521 acataagaaa tataaaggtc tatgatacag atgctaattt tattttgata agagcatata
    17581 aaaaaacaac taaagaattg aaaaaagatt tgcttaagca aggaaacata ttagttagag
    17641 atgcgtctaa ttttatagga ttagatgata gttttataag agtggctata aaatctcatg
    17701 aagataacaa aattcttata gaaaatatga aaaatttatt gggtgattaa aatgaaatct
    17761 tatggaatat gcccagcatc ttgtggagaa tttgtacaag gtataattga tgatgaagaa
    17821 tatttatgtt catatgcaat agatatgtat tctgaagtgt atattgaaga aaaattagta
    17881 gatataaatt tagggagata taagtcaagg ttagcaattg aaaaggtatt tgaaaaattt
    17941 aatttaccta aaaaatatac taaaaatatt tctttaaata taaatagtaa aatacctgtt
    18001 ggaaaaggaa tggcaagttc aactgctgat ataggagcta caataaaggc aacattatca
    18061 ttgatagata aagatttaag tagtgaggag atttctaaat tagcagcaga aatagaacca
    18121 acagattcta tatttataga taaaaatagt atatttaatc ctctaaatgg aactgttata
    18181 aaatacctag gaaatctgac caatgcgaaa gttataatac ttgaaccaaa caaagtacta
    18241 gatactatga aaattagatt gaggcaagat tataataaat taaaagtaga aaataaagaa
    18301 gtaataaaaa aatcatttgc tcttttagaa gaaggattga aaaaaaataa tttatctcta
    18361 gttggagagg cttgtacttt gagtagctta gcaaatgaga atatagaaaa aaaagagtat
    18421 ttaaatgaaa taataaaaat atcaaaaaaa tatggagcat atggagtaaa tattgctcac
    18481 agtggaactg tagtaggtat tttaattgat aagtctatga atgataaaaa gatgatagat
    18541 accttatgtg aatctaacat aaattctgtc tataataaaa tttatacaca aaacataatt
    18601 aatggaggaa ttaaggggga aatagaatgg aatacataaa gaatcctatg aaaatagaag
    18661 aaaaaagttt tgaattgata caagaaataa tagacgaaat tagaccagat tataaattta
    18721 agaataatat tgaagaaaaa ataataaaaa gagctataca tactactgct gattttgatt
    18781 acttagatat attaaaaata tcagaagaag cagttgatag tataatagat gcattaaaaa
    18841 ataatgcaag tatttatact gatacaaata tggctcttag tggtataaat aaaagaaagt
    18901 tagaatcatt aggatgtaag tataaatgtt tagtggcaga tgatgaaact gtaaaattag
    18961 ctaaagaaaa aggaattact cgttctatgg cagcagtaga aattgcagct aaagaagaag
    19021 gaagaaaaat attcgtttta ggtaatgctc caacagcttt atataaagtt atggagatga
    19081 aatcagaagg tagattagat ttagatgcag ttataggagt tcctgtaggt tttgtaggag
    19141 cacaagaatc aaaagatgaa gttgaaaaaa cagatatacc atatataatt tctaaaggta
    19201 gaaaaggtgg cagtaattta gcagcagcaa tagtaaatgc tatattatat actatgtagg
    19261 tacctatatg gaagaatatg tatatataga tggaaaaaaa tatagaagag gatatactac
    19321 aggttcatgt gcaacaggtg catctaaggc tgctgtatat atgttgatta caaaaaatag
    19381 aatcaatact ataaatatag atactcctaa ggggatacca ttactactaa aagttgataa
    19441 tataaatatt tctgatacat ttgtggaatg ttccataaaa aaagatggtg gagatgatat
    19501 agatgcaact cataccatgg atatttatgc aagagctgaa attgtagcta aaaatgataa
    19561 gaacaaaggg tatcttactc taaaggatat agatagttta agcaccaata gtgagtgtaa
    19621 aagtgagctc tataagttta ttagggttta tggcggaact ggtattggtg tggttacgaa
    19681 aaaagggctt agtgtggatg ttggtaaacc tgctataaat ccgactccac ttaaaatgat
    19741 aaaccatgaa ataagaaagc ttataggaga taattttgaa tctatacttg gaaatgataa
    19801 agttttaaaa ataacaatct ttgctccaca aggagaaact gtagcaaaaa aaacatttaa
    19861 tccaagatta ggtatagttg gaggaatatc tataataggt acaactggga ttgttgaacc
    19921 tatgagtgat gagggttgga agaagtctct ttctatagaa cttcagatga aaaaagaaca
    19981 aggcttagat aaaataatat tggttccagg aaatcatgga gaacagttta taagagaaaa
    20041 attaaactta gatattaagt atgtagttag ggtaagtaat tttataggct atatgattaa
    20101 agaagctcaa agaataggat ataaaaaaat cttaatggca ggtcatatag gtaaatttat
    20161 aaaagtatct gctggtattt ttaatactca tagtaaggta gcagatgcta gaagtgagat
    20221 attagtggca aacttagctt taatgggagc tagatacgaa tttttaaata aaataaatca
    20281 atgcgtaact actgaagaag ctgtagagct aataaataat agtgaatata gagaagtata
    20341 taatatatta agtaataaat gtaaggagag agtaaagcaa tacttgaatg aagattcaga
    20401 tgatattgat gtggaagtaa tcatattttc aatggataag tctttattag gtaaatcgga
    20461 taatacagat gatttagtgg aggtctttat atgataaaca taataggtct aggacctggt
    20521 aacttagact atataacaaa aaaaggtgaa aatttaattt ccacttctga tgtattaatt
    20581 ggtggtaaaa gaaatctaga gtctataaaa aattttgaag gagaaaaaat agttctggat
    20641 tctaatttaa gagaaattat agagtacata aataacaata aagaaaagca aatatcaata
    20701 atagcatctg gggacccatt aatatatggg ataggtagat atctatctaa aaatattgat
    20761 aataagatgt taaacgtggt ttctgggatt agttcattac agtacatatt ttcaaaaata
    20821 tatgtagata tgaatgatgt atatattaca agtagtcatg gcaaaatacc agattttgat
    20881 tacatattat cacataaaaa agtatgtatg gttacagatt caaagatagg accaaaacaa
    20941 ataagtagag aaataataga tagaaatcta aataaaatta ttgttgtagg agaaaatctg
    21001 tcatatgaca atgaaaaaat aacaatagcg aaaccagaag agataataag aatggacaat
    21061 tttgatatga atgttgtggt gattttagat gaggaatagt gaatttataa caggtaaagt
    21121 tccaattact aaggaagagg ttagagcaat atcaataaat aagttaaatt tagtaaatgc
    21181 taaaaacctc atagacatag gggctggtac aggaagtgta agtgttgaag ctgcatataa
    21241 ttatcctaat ttaaaggtta tatctataga gaaaaatgat gacgctatag agcttataga
    21301 gaaaaatata aaaaaattca acttaaaaaa tatagaagtg ataaaaggat atgctccaat
    21361 taatctaggg ttaaatgtta aagttgagtc tatttttctt gggggaacag gaaataatct
    21421 ggaagaaata atagaatggt ctaaaaaaaa tctcgttaca ggaggaagac ttgtagctaa
    21481 ttttataata atagatacat ttaatcaaac tttaaaactg cttaaaaagc atggatttaa
    21541 agaaatagat gtatgtgttt tgaatgtttc taaactagag aaactaggaa aaggtgaata
    21601 ttttaaacca ctaaatccta tatatataat atcttgtgaa aaaggggaaa atgatgatga
    21661 ataaagtaca ttttgtagga gcaggacctg gagataaaga gctgataaca ttaaaaggat
    21721 acaaattatt aagtaatgca gatgtagtga tatatgcagg ttcacttgtt aatcctgaac
    21781 ttttggaata ctgtaaagaa gattgccaaa tacataatag tgcacatatg gatttacaag
    21841 agataataga tgttatgaga gaaggtatag aaaataataa atctgttgta agactgcaaa
    21901 caggtgattt ttctatatat ggttcaatta gagaacaagt ggaagattta aataaattga
    21961 atatagatta tgactgtact cctggagtaa gttctttttt aggggcagca tcatctttag
    22021 gggttgaata tacagttcca gaaatttctc aaagtgtaat tataacaaga atggaaggca
    22081 gaactccggt tccagagaaa gaatcaatac aatcatatgc taagcatcag acatctatgg
    22141 taatattttt atctgttcaa gaaattgaga aagttgtgtc taaattactg gaaggtggat
    22201 atccgaaaga tactcctata gcagttatat acaaagcaac ttgggcagat gaaaaaatag
    22261 ttaaaggaac tttaagtgat atagctgtaa aagttaaaga aaacaacata aataagactg
    22321 ctttaataat ggttgggaga tttttaggag aagagtataa taattcaaag ttatatgata
    22381 aggatttcaa acatgaatat agagggtaat attgctataa tctgtattac agaaaatgga
    22441 aaaaatttag ctgtaaagat aaattctcta gtaaataact gtgttatata tcaagtaaaa
    22501 aataaaaaaa gtaatttagt tgttgaagaa acatgtgtac atacagttca aaagaagtta
    22561 agtgattttg taggagaaat atttagcaaa tttgattaca taatatttat aatggctaca
    22621 ggtatagttg tacgaagtat agcaccatac ataataagta agtttagtga ccctgcaatt
    22681 ttggtaatgg atgaaaaagg caaaaacgta ataagtttat tgagtggtca tattggaggg
    22741 gcaaacaact tgacacagta cataagtagt cttattgatg ctaatccagt aataacaaca
    22801 gctactgata taaatcaaaa agcttcctta gatatgatag caaaaaaact aaatgcacat
    22861 attgataatt ttagagaaag tgtaaaagaa gtaaattcta tgctagtgaa taataaatgt
    22921 gttggattat atgttgatga aggatatcaa gttgatacta ggggatttaa acttatagaa
    22981 agtaaggatg agttaagaga tagcttttca aacacatata tagaaaaatt agttgtagta
    23041 agcaataaaa taaattgtat tgaagatatt gagaatttaa acttagataa taaatttgaa
    23101 cattgctata gtactaaaaa aataataaag gtaattccaa gagatatagt gataggaatt
    23161 ggctgtagaa gaaacacaga tagtgagctg atgtataatt tacttgaaga gtttcttaat
    23221 aaacaaaata tagatattag agcaataaac acagttggaa gtatagaact gaaaaaagac
    23281 gaaaaagcaa taattgaatt atcaaaaata ctaaaagtgc catttaaaac attttcaata
    23341 gatgaaatat ctaaggttga taatcttttt gataaatctg attttgttaa aaaaaatgtg
    23401 ggcgtgtatt cagtagcaga acctatagca tatcttttga gcaaaggtaa tttgttagtt
    23461 gaaaaacata aatataaagg aataactttt tcagtgggga gaataaaagt atgatatacg
    23521 ttgtaggaat tggaccagga agtaaagata caatgacttt agaagcaata aaagcaatag
    23581 aagattctga ggctattgtt ggatataaga cttatataaa actaatagaa gaatttatac
    23641 aaggtaaaga aataatccaa aatggtatga ggcaagaagt tgatagatgt aaacaagcag
    23701 tagaggaagc gaaaaaagga aaaaaagtag cagttgtaag cagtggtgat gctggaatat
    23761 atgggatggc aggtctcatt ttagaattaa tatctaaaga agatgaagat ataaaagtaa
    23821 aggtaattcc aggcgttact gcaagtattg gtgcagcagc tatacttgga gcccctatta
    23881 tgcatgattt ctgtcatata agtttgagtg atttaatgac tccgtgggaa gtaattgaaa
    23941 aaagattgag attggctgct gaagccgatt ttgtaatttg tttgtataat ccaagaagta
    24001 agggaagaag tgaacatcta agcaaagcat ttaaaataat gggtgagttt aaaggtggag
    24061 atacacctgt tggagtggta aaagatgtag gtagagaaaa agaagaaaag tttgtatgta
    24121 cttttgaaaa tatggacttt gaaaaagtcg atatgactac aatggttata ataggaaata
    24181 agtctaccta tattaatggt gaattgatga taactccaag aggttataca gtatgatttt
    24241 aattttagga ggaacttcag atagtttatc tatatgtgat aagataaatg aactgaaaaa
    24301 tcaaccatat atcctttcag ttactacaga ttatggaagg gaacttgcac aacaacatgc
    24361 agagaatgta attttaggta agcttggaaa agaagatatg ctaaaattta taaaagataa
    24421 taatatagta aaaataatag atgccactca tccttatgca gttgaagtat ccaaaactgc
    24481 tattacttgt gcaaaattat tgaatataga ttatataagg tttgagagaa aatctttaat
    24541 tgaagaaata gattatgata ataaatttat agtagataca attgaagaag cctgtgaaat
    24601 agcaaataaa atagggacaa atatattcat aggaacagga agtaaaaatt tgaacagatt
    24661 tatagaggaa ataagtgata aaaatttagt tgttagagtt cttccaacga gtgaagtcat
    24721 attaagttgt gaaaaattag gtttaagtgc agataatata gtagctatga aaggtccatt
    24781 tagccagtat ataaatgaag aaacatataa acattacaat atagatttag tcataacaaa
    24841 agaaagtgga atagctggtg ggttcttaga gaaggtaaat gcatgtaaaa ctttcaatat
    24901 accagtaata attataaaaa gagaatcgat taactacgaa aatgtattta atgacataaa
    24961 taaaattaaa gacatacttg tgtaattttt aggaggagaa tatatgaaga aagccttatt
    25021 agtagtgagt tttggtacaa gctatcatga aacgagagaa aagacaatag atatatgtga
    25081 agataaaata aaaaattcgt taaaaagcca tgattttttt agagcttata catcaaatat
    25141 gataataaat aaaataaaaa aaagggatgg aatagaaata gataatccaa tacaggcttt
    25201 agataaaata tatgaacaag gatatgatga agtaataatc caaacacttc atattatatg
    25261 tggcgaagaa tttaacaaat taaaagaaca agtagatgga tattcttcta aattcaaaaa
    25321 gattgtatta ggaagacctt tgcttacaca tattgaagat tatcaggaag ctgtagaggc
    25381 aattaagcat caaattcctc atatggaaag taatgaagca gtagtattta tgggacatgg
    25441 aacacttcat gaatcacatt cagcgtatcc agcattggaa tacatgctta gggataatgg
    25501 aataaatgct tatgttggta cagttgaagg gtatccagaa atagaacatg taataagaag
    25561 attaaaagaa ggaaatataa aaactgtaaa tttgatgcca tttatgttag ttgcaggaga
    25621 ccatgctata aatgatatgg caggagatga agaagattct tggaaaacaa tattagaaga
    25681 agatggattt gacgtaagag ttcatttaaa aggactagga gaaaattctt atatacaaga
    25741 taaatttgtt cgtcatgctg taaaatgtgc agagaatgct aagttttatg gtataggagc
    25801 agggccagga gatggttctt tacttacgat aaaagcggtt aatactttaa agaaactgga
    25861 tattctatac actccagaat caaaaaaggg tggagatagt ctagctttat caatagttag
    25921 tgaatattta cctgaatcag tggaaataaa gtctaggcat ttcccaatga gttttgatgg
    25981 gaatgaaaaa agtttagctt gggacaatgt agcacaagaa attatatcag atgttaatga
    26041 tggtaaaaat gtaggatttg ttacattagg agaccctatg atttatagta catatgtata
    26101 tataatgaaa agaatattag gagaggtaga agtcgaaact ataccaggaa tttcatcatt
    26161 ttccaatata gcatctaatc agaattttcc attagtcatg gataaagaag ctttagtggt
    26221 aattccttgt actatggaag atgataagat agagtatgct ttgcaaaatt ataattcaat
    26281 agtattgatg aaggtatata aaaattttaa agaaataata aaaaaattag aaaagtatga
    26341 tttaatagaa catgctattt tagtaagtaa ttcttcccaa gaaagcgaaa atgtgtttac
    26401 agatttaaaa gaagcgcacc ttgaagataa gatatcttat ttttctacta tactagtaaa
    26461 taaagataat aaaataggtg aaagcaatat ttaaaggaga cttaatatga atatagtggt
    26521 tggaactagg ggtagtaatc tagcgcttat acaaacagag tgggtaataa atgaattaaa
    26581 aaagaagtat ccagaaatta gttttgagat taaaatcata aagacaaaag gagatttaat
    26641 tcaaaatgtt tcactggata aaataggtga taaaggattg tttgtcaaag aaatagagca
    26701 acaattatta gatggaaaaa tagacatagc agtacatagt atgaaagata tgccttctta
    26761 tttagcagat ggactaaaat ttgctcatac gcctaagaga gaagacccaa gagatgttct
    26821 aatacttaga gaaggatata aaaatttaga tgatttgcct catggagcag taataggaac
    26881 aggaagtaaa agaaggaagt ttcaattatt gaaacaaaga cctgatttaa atatagtaca
    26941 agttagaggt aatgtggaaa ctaggatacg aaaaataaaa gatgaaaaca tgcatggtat
    27001 tgtgttggca gcatcaggaa taattagagc taatttgcaa gataaaataa gttcttattt
    27061 acctgttgat gttgttattc cagcacctgc ccaaggagct ttagctatag aaattagaag
    27121 caatgatagt acgatagagg gaatagtaaa ttcactgaag gatgagaata cagaaatcca
    27181 aatattggct gaaagaggtt ttttagatgg tgtaaatgga agttgtcata ttccaatggc
    27241 agcttattgt gaaataatcc aagataaaat acatcttact ggcttatatg gagattcaga
    27301 aggaaaaaaa gtagtaatca agtctataga tggagatatt tcttctccta gagagttagg
    27361 tttaaagtta gctaaacttg tattgaagga gtatgagaat tatgaagggt aaggtttact
    27421 tagtaggggc aggaccaggt gattataaac tcatgacttt aaaaggttta gagtgtataa
    27481 gaaaatcgga tgtaatagta tatgatagat tagcaaatag tagttattta agagaagcta
    27541 agcctgattg tgaacttata tatgtaggca aggcatcaag taatcatatt ttgccacaag
    27601 aagatataaa tagaattata gcagaaaaag ctaaagaagg aaaaattgta actcgtctta
    27661 aaggaggaga cccttatgta tttggcagag ggggagaaga agcagagact ttagtagatg
    27721 aagatataga atttgaagta gttccaggta taacttctgc tataggaggt ttatgttatg
    27781 cgggtattcc tataacacat agagaccatg cttcgtcatt tcatgtaata acaggtcatt
    27841 tgaagggtga tgatagtgga gaattaaact ggaatgctct tgcaaataac aaaggtactc
    27901 ttgtgttttt gatgggaatt tcaaacctag agaaaataag tgaaaactta atgaaagaag
    27961 gaaaagataa ggatacacct gttgctctta taagttgggc aactagatat aatcaaagag
    28021 ttgttacatc tacacttgag aatgtttatg aaactgctat taaagaagaa gtaaaaccgc
    28081 caactcttat agtagttggg agtgttgtag gacttagaga aaagttgaac ttctttgaaa
    28141 gtaagccttt atttggaaaa agtattgctg taactaggtc tagaaatcaa aatagtgtat
    28201 tggtagaaaa aataatggat ttaggtggaa atcctataga aatacctact attaaggtag
    28261 aaaaaataca aaataatatt aacttagaaa atgaaataaa aaatataaat aagtataatt
    28321 atttaatact aactagtaaa aatgccgtag aaatcttctt tgaaaagata tatgaaatga
    28381 attttgattt aaggatatta tctaatttaa aggtatgtgc tataggttct gctacatcaa
    28441 atgagttgaa aaaaagagga attatagcgg atatagtacc aaaaaaattt gtagcagagt
    28501 cactgtatga agagttagct cctattttaa atgataacga taatatactt atacctagag
    28561 cagaaaatgc tagagattat ctggttgaca aacttaaggc tatttgtgaa gtaacagaag
    28621 tacatatata tagaacagta atagatgagg ataaaaaagg tgagatatta gatattttaa
    28681 attctaatga tatagattat ataacattta ctagttcctc aacagtaaat aatcttgttg
    28741 aaattatagg aaaagaaaat attaaaatat tagaaaaaat aaaaacacta tctataggtc
    28801 ctataactac agagacaata aatagtttgg gaataaaatt gtacaaagaa tctgctacat
    28861 ctactataga ttcgttagta gatttaatta taaaaaatta attttggagg cttgaatatg
    28921 ttaagaagac caagaagact aagagcaagt aaagcaatca gaaatttggt aagagaaact
    28981 aaggtgaatg tagaagattt aatatatcca ctgtttgtag tagaggggga aaatataaaa
    29041 gaagaaatta aatctttacc agatgtatat catttatcaa tagacatgct agaagacgaa
    29101 ataaaagaaa taagtgagtt gggaattgaa catataatgt tatttggtgt tccagatgaa
    29161 aaagatgagt gtgcttcaca agcttttaat gataatggaa tagttcaaaa ggcaattaga
    29221 aaggtaaaag aaataaattc agatataaat gtaataacag atgtctgtat gtgccaatat
    29281 acaagtcatg gacattgtgg gattttaact gatactggtt atgttgataa tgataaatca
    29341 ttggagtatt tggctaaaat atctgtaagc catgctaaag caggagctga tatggttgct
    29401 ccatctgata tgatggatgg aagaatacaa gcaataagag aagctttaga tgaaaatgga
    29461 ttagaaaatg ttggaatcat ggcttatagt gttaagtatg cttcaaatta ttatggacct
    29521 tttagagagg cagctcattc agcaccatct tttggagata gaaaaacata tcaaatggac
    29581 ccagcaaata gcaatgaagc tataatagag actgaacttg atatattgga aggtgcagat
    29641 atacttatgg ttaaacctgc attatcatat ttagatatta taagaagagt taaagataat
    29701 tttgacttac ctctagcagc ttataatgta agtggagaat actctatgct taagtttgct
    29761 gtgaaggaag gtttattaaa tgaagatgta attcttgaat caattacatc tataaaaaga
    29821 gcaggagcag atataataat aacttatttt gctaaagaca ttgctaaact gttgaaaaaa
    29881 taaattctag tagtataaag aatatcaaaa agtataggaa ttgtaattaa ctattataca
    29941 gtagttttgt ttagacattt attgaagaat aatagaaact aatttacaat ttctatactt
    30001 tatttatgta actaaataaa atttggaggt agaagatgct atatcctatt aatttaaaat
    30061 tagatgagtt agatgtagtt ataattggtg gtggagaagt tgcatatagg aaatgtaaaa
    30121 attttttaga gtttaacaaa aatgttacta tagtttctaa acaaatttta aataaatttt
    30181 atgatttaaa aggaaatata aaaataataa aagatgatta taaagaaata tatataaaag
    30241 atgcttctgt aataattgct gccacaaata atagagagtt aaatatggaa ataggattat
    30301 attgtagagc aaaaaataag ctagtgaatg tagttgataa tatagaaata tcgaacttta
    30361 ctgttccatc atatataaaa agaggagatt tacttataag tgtgtctact gggggcaaga
    30421 gtccttcatt atcatcaaag ataaaaaaag aaattgaaga gagatatact gaagattatg
    30481 aggagtattt aaatgtatta ggagatataa gaaaaaaggt tataaaaaaa tacgaagata
    30541 aaagtaaaag aaaagatgta cttaatatgt tggtaacact tgacctagaa gaacttaaga
    30601 agtttgatat ataaaaaata aaataaaaaa tgttaaaaag gtgttgacgg a
//
LOCUS       DACTZW010000043        30360 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.043, whole genome shotgun sequence.
ACCESSION   DACTZW010000043 DACTZW010000000
VERSION     DACTZW010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30360
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.043"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(96..698)
                     /locus_tag="JAM15_10690"
                     /pseudo
     CDS             complement(96..698)
                     /locus_tag="JAM15_10690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427254.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ChbG/HpnK family deacetylase"
     gene            complement(691..2139)
                     /locus_tag="JAM15_10695"
     CDS             complement(691..2139)
                     /locus_tag="JAM15_10695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAT6798721.1"
                     /translation="MKRFLNKMMQQLSLLGKTMLVPIAVMPAAGILGLLFGPNMLNVP
                     AISNISNIVFSNVDYLFLLGAVSAYSKSKDKTSVMVAAVVAYMIFKSNLELLNDTLNA
                     GVFGGIIVGACIAWTYNKTYKVKVPAFLSFFAGEKCVITLSPVVALILSYIFSLLWIY
                     PQAAMNQFGFWLGGAGAIGIFLFLFCNRALIPTGLHQVLNAYILFEMGEYTTSTGEVI
                     RGEIPRFMAGDPNAGFFWTGFYIIMMFSIPAISYAIYKTAQDKKKQEVKGAMTAGALT
                     SFMATVTEPIEFSFLFASPKLYIIHSFYSGLGGVVLYLLGARLGSFNGASIIDYVLSF
                     SYGDKAWLVIPVGVVFFVLYYVTFKYIIIKDNVQTPGREVEIEIGDKVSEKEKNLKLS
                     HGNFSYMAKQIIKNCGGYENIVTLNNCMTRLRLEVKDATILNDDNIKKTGAKGVIKLS
                     NTSVQIIIGTDVVKVKDEMEMQLDELRKQADA"
     gene            2509..3231
                     /locus_tag="JAM15_10700"
     CDS             2509..3231
                     /locus_tag="JAM15_10700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAT6798722.1"
                     /translation="MAKNKFSEIYEVLKEEILDGKYTSNMMLPTELQLIERFSCSRNT
                     VRRAISQLNTEGYVQSIKGKGVVVLENSCSNDFFLNMHNFKGVESIVEDKKVNTATSV
                     LHFSKILIDNKLSKKTGFKVGSEVYYLHRLRYIDNIPKILDINYFLCSIVKDLDVSIA
                     QGSIYKYIEECIGTKIVSSRKIFKIEKATELELKTLPLNDYNCVGVIKNSVYTDDGKL
                     FEYTESKHTPETFVFMDVTQRY"
     gene            3428..5095
                     /locus_tag="JAM15_10705"
     CDS             3428..5095
                     /locus_tag="JAM15_10705"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HAT6798723.1"
                     /translation="MKNWWKKATVYQIYPKSFKDSNNDGIGDINGIIEKLDYLYSLGV
                     DLLWLTPMYVSPQRDNGYDIEDYYNIDPKYGTMSDFEKLLKEAHKRDIKIMMDMVLNH
                     TSTEHKWFKESKKSKDNPYRDYYFWKDAKPDGSVPNNWISRFSGTAWKYDETTNQYYL
                     HLFEETQADLNWENEKVREECYKVLEFWADKGIDGFRLDVVNLLSKTPGLPDDPITGP
                     KGDGRTHYADGPRIHEYLHNMNQKVFKPKNIVTVGEMSSTTPEECINYTRENREELSM
                     VFSFHHMKTDYKGGAKWTNEMFSLDKLKKAQSDFQYKMYEGKGWNALFYSNHDQPRAL
                     SRFGDDRFFRQESAKMLAITLFGLQGTTYIYQGEEIGMTNAYFTKIDEYDDAESKNAY
                     YHMIKSGIDEKEALLILQQKSRDNARTPMQWDNTIYKGFSNHKPWLKVNNDNISVENE
                     LNDSRSVFYTYQRLIKYRKQYDIFTEGTYRLLDENHKNLFVYEREYKNQNLLVISNFT
                     HDNVVYKLPETYLNKLNYTILETNYTRDIIENKMEIKPYESIMIYYK"
     gene            complement(5191..6510)
                     /locus_tag="JAM15_10710"
     CDS             complement(5191..6510)
                     /locus_tag="JAM15_10710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAT6798724.1"
                     /translation="MEKGIKLGFWSIVLLGINAIIGSGIFGLPGDAYTDIGPASILVL
                     VFCMLLAVSIALCFAEAGSWFDTDGGPYLYAKEAFGDFVGFEVGFMKWIVSMIAWATM
                     ANFFAVTLSSVWPQAAEPLTKNIIIGILVVGLGIINFMGMKQSKHLNNIMTIGKLLPI
                     VLFIAVGLFFIKGSNFTPFVIIQKGQSASSAFVAVSITLFYAFTGFESLAVAAKDMEN
                     PKKNVPKALVMVMFVVSVIYMLILGISIGVLGNGLAGSATPVADAAIKMLGPIGGYII
                     TIGTIVSVGGINIASSIFTPRSAAALVEQGLMPKSIRKTNKNGAPYIAIIVSVIGTLL
                     IAWSGSFTTLSQISVVSRFIQYIPTCLAVLILRKKYADKDVNFRIPGGAIIPIFAVII
                     SILLLIKAGIDEPMKIVWGLGGMIIVVPIYFYMTKVYSKKYNDVEVK"
     gene            complement(6551..7297)
                     /locus_tag="JAM15_10715"
     CDS             complement(6551..7297)
                     /locus_tag="JAM15_10715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HAT6798725.1"
                     /translation="MKKLVKKKYPIIGISGNLLIDEGGMFPGYERAYVNNDYIQSVVM
                     CKAIPYIVPIVYDDEIIKEQVSNIDALILSGGQDVNPLIWKEEPHNKLRAISPKRDSF
                     DMKLLKHALDMKKPVLGICRGEQIINVTEGGSLYQDLSLIEGAYIKHNQQHLSNVPTH
                     TVQIKEGTKLYEILGEKEVLVNSFHHLVVNKVAPGYIVSATSKDGLIEAIEKEGSEFV
                     IGIQWHPEMMTRDYDNMKKIFMAIVKEASK"
     gene            complement(7541..9550)
                     /locus_tag="JAM15_10720"
     CDS             complement(7541..9550)
                     /locus_tag="JAM15_10720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAT6798726.1"
                     /translation="MKTIAVVTDGLSKLECFLNKNLEMIFKDKVKIKNYYLNKITEKE
                     LIKDDIILVMIDDRVLKIKKYVEDVSKIITINRSIKQKDIYKLFSLPEEIDVLVVNDN
                     KHTVLETISNLYNIGINHLNFIPYNPNEEYRNIKIAITPGESSLVPKYIEEVIDLGHR
                     YIDSSTFIQIIAKLKLDDKEITERLIKYTDEIISLYSGINTKYKELTIKADELNSIIN
                     LSNLGMAMVSDKGNIIICNNSLRDILDIQSNIIGKNIDELENENIKKIFSLSKAHDEV
                     IKFNNKYLNVNKYNIESFGKVTGYYFCIQEITYIRKLEQNLSKKLREKGQVARYTFDD
                     IKTVSMKMERTKKLGMKIAESDYTILITGESGTGKELMAQSIHNASPRHSQPFIAINC
                     AAMPENLLESELFGYEEGAFTGALKGGKKGLFEQANNGTIFLDEIGDMPIYLQSKLLR
                     VLQENQVMRVGGENVIDIDVRVIAATNKNLLEMIKGDRFRADLYYRINVLPINIPPLR
                     ERKEDIEVMLKHFMKRKRAISQDVQDIINAYEWPGNIRELKNTAMYINIMSSEDVILI
                     NDLPHNLLNITEDFSKEISILKDRTSIEKVKLVMECLKNANNLNKNIGRNGIVNSINE
                     LGYSITEGEVRGILNMLKELDLIICESGRKGSELNRRGKNILNSI"
     gene            complement(9988..11421)
                     /locus_tag="JAM15_10725"
     CDS             complement(9988..11421)
                     /locus_tag="JAM15_10725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAT6798727.1"
                     /translation="MVLRKDFLWGGATAANQCEGAWNLDGKGPSCSDMCTGGSQKVSK
                     RITRVIEKGTFYPSHEAIDFYHRYKEDIALFAEMGFKVFRFSIAWTRIFPTGMEKEPN
                     EAGLKFYENVIDECLKYNIEPLITISHYEIPFAITEKYNGWVSREVIDLYMNYCETIF
                     KRYKGKVKYWLTFNEINSATMPMGGYLSQGILNEGTTDFINQVDIPQLRFQGLHHQFV
                     ASAKAVKLAHEIDSNYQVGCMQIFATMYPYTCNPDDAVKTQRDSRVMNYFCGDVQVRG
                     EYPTYMNRYFGENNIEIKMEKGDLEILKEGCVDFYTFSYYMSTCVSSDSKEDNTSGNI
                     LGGVKNPYLKSSEWGWQIDPEGLRYALNEIYDRYRIPMMVVENGLGAYDKKESNGVIN
                     DDYRIEYLKAHIEQMKEAVEDGVDLFGYTPWGCIDLVSASTGEMAKRYGFIYVDKYDD
                     GSGDLSRIKKKSFDWYKQVIESNGERL"
     gene            complement(11508..13424)
                     /locus_tag="JAM15_10730"
     CDS             complement(11508..13424)
                     /locus_tag="JAM15_10730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAT6798728.1"
                     /translation="MRRYEQLSKEIIENVGGKDNISSLSHCITRLRFKLKDESIANDD
                     VLKKMDGIVTVMKSAGQYQVVIGNHVPDVYEVVCDLAGLGGDTIDNSDSDAPKGLLNK
                     FIDIISGVFQPILGVLCAAGMIKGFNAVFTALGLYGETDGAYIMLNAIGDAMFQYMPI
                     ILGYTAAKKFKLKPFIGMLIGAVLCYSGIQLDTLASIGQPLYNLFTGTIFESPVYITF
                     LGLPVIAMNYTSTVVPVIIIVLLAAKLEKVFAKIIPDVVKNFFVPMAVLLVSLPLGFM
                     VIGPIATYASNIVGNGFLALFNFSPILSGVLTGLLWQVLVIFGLHWGLVPIAMSNLMT
                     MGFDTILVGAFVPSFAQTSVVAAMYFKLKDKKIKELCIPAVISGICGVTEPAIYGITL
                     PRKTPFIYSCIGGAVAGAVMGIMNVKNYVMGGLGIFGIPNYINPTTGDMKGVYATIIA
                     IIVAIVVGFVLTLFFWKDDSIVEISKDNNGQGVVEKNKREVVYSPIKGEVKALEQIQD
                     AAFSTGILGKGVAITPKEGKVVAPFDGTIMTLFPTKHAIGIISDNGCELLIHIGLNTI
                     QLEGKHFKSFVNQGDKIKKGQTLITFDIESISKEGYCLETPVVVTNYSDYVDIIENTQ
                     KHVNNSQELITVLA"
     gene            complement(13498..14358)
                     /locus_tag="JAM15_10735"
     CDS             complement(13498..14358)
                     /locus_tag="JAM15_10735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAT6798729.1"
                     /translation="MIIEKILNNNVIITTDENHKEIVVMGRGLAYKKRTGEHISKDKI
                     DKIFKLSDPNISDKFKELIADIPIRYMELSDEIILYAKEKLGKRLNDSIYISLTDHMY
                     TAIERAREGVSVKNVLLWDIKRFYKSEFKIGLEALDYIEKKFEIRLSEDEAGFIALHI
                     VNAQMDQSIKTIYEITRIIQEISNMVKYHYRIVFDEDSVYYHRFITHLKYFAERIVSN
                     NLHENNEDDLLNVIKVKYKNAYKCIEKLDEFIHKKYNYDLTDEEKLYLTIHVERVVSK
                     SIKSDINPNN"
     gene            complement(14708..15895)
                     /locus_tag="JAM15_10740"
     CDS             complement(14708..15895)
                     /locus_tag="JAM15_10740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HAT6798730.1"
                     /translation="MIESIKKRAYEIENELGKEIEEVCNFIFNNPELGEEEYISSKYL
                     VKKMKEYGFDTVYPYCNMETAFRAELGDNDGPTIAFLAEYDALPGYGDNKEPAHACGH
                     NWIAASTLGACIVLSKLKENFKGKIVLIGTPAEETTGGKCDLVKAGAFDDVDVSYQMH
                     IEAFNNINCKALAIDSLEFSFEGVSAHAASHPHMGVNALDAVQLTFAGINALRQHVKS
                     DVRIHGIVSNGGEAPNIVPEKAACKFFVRAAERSYLDEVTKKVINCAKGAELMTGAKL
                     SYRYFENSFDNIINNKVLQKITKNNLIEAGITDILEGKDGPVGSTDIGNVSQVCPTMY
                     TEIALDISPMVYVHEKEFLNYANSEEAYDKLHKAVKAMVGCALEIYLEDGLLDEIKKN
                     HLN"
     gene            complement(15909..17300)
                     /locus_tag="JAM15_10745"
     CDS             complement(15909..17300)
                     /locus_tag="JAM15_10745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HAT6798731.1"
                     /translation="MSSLKKKKFTMPQTLTIIFLLIVLMAILTWIVPSGNFERVDIDG
                     RSVVVAGTYEKAPSNPQGITDVFTAPINGFIDAAEVVGFVLIVGGAFGIVNKTGAIEA
                     VIAHTVNKMKKFQFLIIPISMILFGLGGTTFGMSEETLPFYMIFIPLMTSMGYDSLTA
                     VATVFIGATAGFGAATTNPFSVGIAQALSQIVPGSGIEFRVVMFIIYMAISIGFVMMY
                     ANKVKKDPKKSLVHDISLNQESMVNSDTNIKEFTKREAMVIAIFTIGMAIMIYGVLRL
                     EWYITEIAMIFTAIGIISGIASGLKQDEIVNSFISGAGDLITAGLCIAFARGIVIIAE
                     NGFIIDTILNSAANLLNGLPKTIFINLTFLIEGLIAFLIPSASGLASLTIPVLAPLGD
                     LVDVSRQMIVTAYQFGIGVTNLITPTSGVLMGALAVANIPWSKWVRFVIPLMVVLTIL
                     VMVFLTIGLYLGF"
     gene            complement(17895..19595)
                     /locus_tag="JAM15_10750"
     CDS             complement(17895..19595)
                     /locus_tag="JAM15_10750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAT6798732.1"
                     /translation="MHYIAWHFNKNGGNNTMKDKLQVLSGAMMIPVILLVVAGVFIGL
                     GSAFANMENVSALGLSGLIKEGSFINVFFKVINDLGFMVMRYLPIFFVTGIAFGLSKK
                     EKGWGALGGIVLFIGMHTVISTLLASNGINSDTVTAEAFMASGLGEAEAYSRSSLYGS
                     FLGIFSYDCSIFGAIIAGFVASAVHNKFVDIELPSALSFFSGPRFSMIMMFIASIVLG
                     TAMYFIWPPVGLALSKLGNWIGSSGLLGTFTFGAMDKALLPFGIHHLIAFPIEYTRVG
                     GTMEVGGAIYEGVNNIRLAQMGDPDTLSYITRNFTTGRLLIHFAILPAAALAMYKLAD
                     NANKKKAISILIPAIVTAMLVGVTEPIEYTFLFVAPLLYFVAYVPLAGLTYVFTEMFN
                     VSIMGESFRNMFPNLLQPQKVDALPLLFLIPIFFIVTYIIFTWAIKKFDIKTPGRSSE
                     EVKLYSKKEYRERQSVDAGKTAYNNAVEEEVDDKDTKLVHSIIEGLGGSNNIKNVTNC
                     ATRLRVELNSIDGFYEDGFWVNELGASGVVKKKNSVQVIFGPRVITIASKLKAVLGVD
                     "
     gene            complement(19567..20970)
                     /locus_tag="JAM15_10755"
     CDS             complement(19567..20970)
                     /locus_tag="JAM15_10755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HAT6798733.1"
                     /translation="MIVNKELIIDYLKSNQENIINDIRSLVEIPSIRDESTTDINQPF
                     GIKIRNAFDKLIQIAKDKDFVVKDFDGYAIHIEYGEGDEVVGVLNHIDVVPIYNKELW
                     KSKPFKVCQKDNYLYGRGVNDNKGPLIGILYALLFLRELNEKPKRKIRLIVGGAEETT
                     WECMEHYFSVNEQPKFAFSPDGNFPIVNGEKGILYFNLRKKIDKDKFRNHNLVDIKSN
                     KEDGFVCDKIEAVFKTDDKKDLVESLAYYTEIEELDEGKVLVRYTGERALSRNPHRSY
                     NCAFSLAKDLEKIKKLNDKGVIIRDILNSYFTDDNHGKKLGIYKEDVDMGVSTICIMS
                     IFLEKNELNMKIDFRYPKGISWEFITNRINEIGKKENLIVDIYKDLKLLYVKPDSELI
                     NKLSSAYKQGFGKEAELFTKGAASYARVLKNGVAFGPTIEGDNPNSHQANENISIDTL
                     YKAIEVYIYALYSLAFQ"
     gene            complement(21234..21725)
                     /locus_tag="JAM15_10760"
     CDS             complement(21234..21725)
                     /locus_tag="JAM15_10760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAT6798734.1"
                     /translation="MFNIFKKKENKIEKIYSPFKGNLVNLEDVPDAVFAQKMMGDGVA
                     IIPSEGKLYSPVDGEIVNVFDTKHAIMIKSNDNTNILIHVGLETMSLEGKPFDVKVKA
                     GDKVKAKDLIMEVDLDFITSNDLNIITPVVIMDDADSVKRTVKDRIEPGNVDINSIIM
                     EVE"
     gene            complement(21751..22563)
                     /locus_tag="JAM15_10765"
     CDS             complement(21751..22563)
                     /locus_tag="JAM15_10765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAT6798735.1"
                     /translation="MRYKLICTDMDGTLMGKGFEVSEENIKALKEAMEKGIKVALVTG
                     RPYNAMKYFTSVLGDDIYIISTNGTYFKLLGYEYKKVLSKEALKKIYTIGEKYNLNKH
                     FKGCKIVISNNEIGEEHPYRLINSKNKEEDRIEIIENASCETLLEKADNEILKCILFS
                     ENVDSLREAKEEFKKQEDLEVVSSGKINFEVMSKGTSKGIAVKKFCDILGIDSKEVIC
                     IGDNENDISMIKFAGLGIAMGNATDEVKSMADFVTDTNVNDGVAKALRKILS"
     gene            complement(22576..23727)
                     /locus_tag="JAM15_10770"
     CDS             complement(22576..23727)
                     /locus_tag="JAM15_10770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HAT6798736.1"
                     /translation="MINFYQPSRINFGQGTLSELPRIIGKYGKKCLLVTTPNVEPLDK
                     LYKRVTLNLIEKGIEVVHFDRVEPNPTVELINEGFELAKKESVDVVLAVGGGSSIDTA
                     KVLALTFGLEKIDWDYMFSTYTNPFKIYDKVSEKELPLIAVSTTSGTGSQVTQAAVIS
                     RGSEKNTIFHQNCFSKECIVDPELMLTLPERITASTAFDAFTHAFESYINPNANDFTE
                     IMSEKSMELVINYLPKVMEDKNNIEYRTKLAVADTLGGSSLANAGAAAPHPLSEIIGG
                     VTHIPHGEALAIVFPKFAEKFYKDNIEKFAKVARMLNQELEKVEDDEAAKTLGNEIES
                     FLKRVGLKTKMSEFNVTKEQLEQITSCPVLGFLPFGKKEDLVEILEKSY"
     gene            23997..24638
                     /locus_tag="JAM15_10775"
     CDS             23997..24638
                     /locus_tag="JAM15_10775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HAT6798737.1"
                     /translation="MKYLIDSANLDEIQKCLKYGFKGITANPSMYLKEKVNFHEFIET
                     CTNLNPEILTAEVIGNNLYELINSCDKILNINKNTIIKINFSEVGLELINILNSKGVK
                     TACTLIFNVNQASLAINAGADYLFPFIGRNDENGNDGIKNLTEICNLISINGYNTKVV
                     AASIKNVFHLTQASLCGCDYAAVTYDLFKKASFNQLTVDGANTFERDWSKVNK"
     gene            24664..26208
                     /locus_tag="JAM15_10780"
     CDS             24664..26208
                     /locus_tag="JAM15_10780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HAT6798738.1"
                     /translation="MNKRLLDIAELLLNSSDYITVDTIAEELKVSNKTIRNDLVILDE
                     WLLEFNLSLDKKTGSGVIILGNEDIKLKVIRDINDKSNCIYAYSPEDRKRYILSKLFI
                     KNSKFRIRDICNELHVSRATVHKDLVVIQNFLQNFKVTLVRKTNNGVYLEGKEKDIRK
                     AIFELATVNKSYTELKEILFSNSNECKDTPSTKIFKELFNYDFEKLSQITLHTLQVEK
                     SNLSDEYYINFLIHIAICIKRISIKRYINLSEGFFRELLEHEYFEKSKILCANLSEAF
                     DVEFIDEEVCYILLHIEGLLKSIKKTTTLEPLKNEEITEYNLSEAIAVHWGSILNLNL
                     KDDLILIKSLANHLKSVLHRINYGFTITNPILNDIKRTFPYTYKAAKESNTVIKQLMN
                     YEVNDDEIGYLALYLISAIDRSKSPLNTILICHCSDGVSNLLVQKLSFEFNQINIVKS
                     IPLSSISFTNFDDVDLILTTAPVDFEHNAELININALLSKNDISRLSTIIKKLYSEKN
                     KILSYK"
     gene            complement(26408..27034)
                     /locus_tag="JAM15_10785"
     CDS             complement(26408..27034)
                     /locus_tag="JAM15_10785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAT6798739.1"
                     /translation="MKKEMIKDYLLITISAFLMALAVNFFFAEHTLAPGGITGLSVVL
                     STFLSMPVENISLGISMPLLVMGLLFLGKGFGIKTLYITLMGPLFLKVIPQTHITDNL
                     LVAGVIGGLLVGTAIGIAIIRGCSTGGTDLVAMLINKVIKFLKLPVILFMLDGFIIVA
                     SGIISKNFMISIYSLISLLLIIKTIGFVTTKFGKNTEEINNINNACAQ"
     gene            complement(27169..27885)
                     /locus_tag="JAM15_10790"
     CDS             complement(27169..27885)
                     /locus_tag="JAM15_10790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentose-5-phosphate 3-epimerase"
                     /protein_id="HAT6798740.1"
                     /translation="MKHIKIAAGLAHVNYGHISAVVKEAMDAGVDYVHSDAADMHDLK
                     NMQLMGGHQIIEAIRPVTDKPIECHIYTRDCDRLFIEKIAAAGCNLLIIPAEHFLGAP
                     LAYIINYCREFGMKVGLTIGCYTPLCFVDEAIYDIDRLQIVVHGVDETDGKDNWGWRK
                     SAVDLVKRARKMIDEKNPKCELAIDGGLRADNMEPLIECNPDVVILSSAIFKDKDGIT
                     AGVKNCRKAIDEAATKFGLE"
     gene            28300..29514
                     /locus_tag="JAM15_10795"
     CDS             28300..29514
                     /locus_tag="JAM15_10795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HAT6798741.1"
                     /translation="MRNCIIAQSGGPTAVINASAVGIYEKNLETKYFDKVYFGINGIE
                     GILNKNIIDSDSLNKDNVLNLKQTPSSGLGSCRYKLADYKINSYDYDRVINILDEYEI
                     DTLFYIGGNDSMDTVMKFSQYCKNTTCKIKFIGIPKTIDNDLLGTDNCPGFGSAAKLI
                     STLIMETYLDFSIYKNNGIFIVETMGRDTGWLAASSSLARLNDTPLVDLIYLPEIDFY
                     EDKFIEDVRKIFKEKNKAYIVASEGIRDKYGNFICEQKTSAHDKFGHSQLGGVSNYLK
                     NLIVSSSITTRVKTLELGVIQRCAMHLASDTDLKQAAEVGAYGIELSKKGYTGVMAII
                     NRTCNNPYKYEVSHTDISKIANKTKYFPKEWINEEYNYITDEALNYLYPLIQGKPDIK
                     YKNGLPYFSIIY"
     gene            30133..>30360
                     /locus_tag="JAM15_10800"
     CDS             30133..>30360
                     /locus_tag="JAM15_10800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798742.1"
                     /translation="MMKIAVITTEFLKEFVDNSIKKLNINAEIEIYIYRDFSHVGDLY
                     LEIEDRFDGFAVSGPIPKKAITKKAGTIKKPL"
BASE COUNT        10130 a         5283 c         3458 g        11489 t
ORIGIN      
        1 ctatcctatc tctacatata agtttcccta tatactgact aatttagtta ctaactcatg
       61 actaaagtca caagtgtgcg tagctatttt ttaatcaatg ttatatcttt atctaaattt
      121 atatattttt cttcaaataa tttaacaaaa gatttattta acttgtaaaa atcattctga
      181 ggatatttac ttggcatgct aatacatgaa tctaaataat agggacaact tggtataccg
      241 tattcttttg cagcatcaca cattgctgat attgatacat cttcttctat accatgtata
      301 tcaatatact caggcaattt actcatatac aacttgtaag tttcaatttg agcacaaact
      361 tcttcatata cttcttcata attaaaaacc tctttacctg tcagtagttg cgttcttctt
      421 attttgctag aaacaaattt tccaccttca tctaacaaat tctttatctt aatatgttct
      481 ttacaacaag gttctcctat tactaaatta acatgtaaac caaaacatac atcatcattt
      541 tttaccattt ctatagcttg tcttgaaaaa ggcatattca ccatgattcc agcacttgta
      601 acaataccgt tcttataaga agatattatc cctagtgtaa caccttctga atatcctata
      661 tcatctgccc taactactaa tttcttcatt ttatgcatct gcctgctttc tcaactcatc
      721 aagttgcatt tccatctcat cctttacttt aacaacatcc gttcctatga tgatttgaac
      781 tgatgtatta ctcaatttaa ttaccccttt ggctcctgtt tttttaatat tatcatcatt
      841 caaaatagtg gcatccttca cttctaaacg taacctcgtc atacaattat taagagtcac
      901 tatattttca taaccaccac aatttttaat tatctgctta gccatatatg aaaaattacc
      961 atgagaaagt tttaaattct tttctttttc actaacttta tcacctatct ctatctcaac
     1021 ttcacgtcct ggtgtttgta cattatcttt tattattata tatttaaatg ttacataata
     1081 taatacaaag aatacaactc ctacaggtat aactaaccac gctttatctc cataactaaa
     1141 acttaagaca tagtcaatta tacttgctcc attaaatgaa cccaagcgag cacccagtaa
     1201 atatagtaca actccaccta gaccagaata aaaagaatga attatatata actttggaga
     1261 tgcaaataaa aacgaaaatt ctattggttc agttactgtt gccataaaag aagtcaatgc
     1321 tccagcggtc attgcacctt ttacttcttg cttcttttta tcttgtgctg ttttatatat
     1381 agcataagaa atagcaggta ttgaaaacat cataattatg taaaatcctg tccagaagaa
     1441 tcctgcattt gggtctcctg ccataaatct aggaatttct cctcttataa cttctcctgt
     1501 tgatgttgta tattcaccca tttcaaataa tatgtaagca tttaaaactt gatgtaaccc
     1561 agttggtatt agtgcacggt tacagaataa aaacaagaat attcctattg caccagctcc
     1621 tcccaaccaa aaaccaaatt gattcattgc agcttgtgga tatatccata ataaactaaa
     1681 tatatatgat aaaattaaag caaccactgg tgatagtgta attacacatt tttctcctgc
     1741 aaagaagctt aaaaatgctg gaactttaac tttatatgtt ttattgtaag tccatgctat
     1801 acaagctcca acaattatcc caccaaatac acctgcattt aatgtatcat tcaataactc
     1861 taaatttgac ttaaatatca tatatgcaac tacggctgca accattacac ttgtcttgtc
     1921 tttagacttt gaataagcac taactgctcc taataaaaat aagtagtcca catttgaaaa
     1981 tactatatta gatatattag atatagctgg cacattaagc atatttggac caaataataa
     2041 tcctaatata cctgctgctg gcattacagc tattggcacc agcatagtct ttcctaaaag
     2101 tgacagttgt tgcatcattt tgtttaagaa cctcttcata tccaatcccc tttctatttc
     2161 ggtttaattt tttgtgaaaa cgatttattc acattttata ttttaaatat tatatttgtt
     2221 taaacaaatt gtcaatattt tttattcatt ttatttttat catttagttt catatctaaa
     2281 tccttttaag tatattgcta tatctagcct attttttaaa tttatttttt ttatttttaa
     2341 aatatgttta accatgtatt tgaaacaacc cacaaaatag ttcaaattta tcctttttat
     2401 ggtttatata attctatttt cactatacat gtctaaacac atttgatata atttgttcat
     2461 atcagttcaa taatattact aaagaccttt aaggagggat aggggtatat ggctaaaaat
     2521 aaattttcag agatatatga agtattgaaa gaggaaatac ttgatggtaa atatacaagt
     2581 aatatgatgc tgcctactga acttcaactt attgaaaggt tttcatgtag cagaaacact
     2641 gtacgtagag caatttctca attaaacaca gaaggatatg ttcaaagtat aaaaggcaag
     2701 ggtgttgtag tgttagaaaa tagttgttct aatgattttt ttctaaatat gcacaatttc
     2761 aaaggtgtag aatcgattgt agaagataaa aaggttaata ctgctactag tgttctccac
     2821 ttcagcaaaa tcttaattga taataagtta tctaaaaaga caggttttaa agttggtagt
     2881 gaagtatatt accttcacag actaagatat attgataaca tacctaaaat tctcgacatt
     2941 aactattttc tatgtagtat agttaaagac cttgatgttt ctatagcaca aggctctatt
     3001 tataaatata tagaagagtg tataggtaca aaaattgttt catccagaaa gatatttaaa
     3061 attgaaaaag ctacagagct tgagttaaaa acgctacctc taaatgatta taattgtgtt
     3121 ggtgttatta aaaatagtgt atatactgat gatggaaagc tctttgaata tacagaatca
     3181 aagcatacac ctgaaacatt tgtattcatg gatgttactc aaagatatta aaaaaattat
     3241 gtttaattaa acataatttt tttacgttta gacactttat cccatactaa cctcactatt
     3301 ctatatacaa ttatatgttt atacaaataa ttatttattg tatattttag ctttaatatt
     3361 agtttaatac ttgacaattt gtttaaacat attataatta acttataaat tacaggaggt
     3421 atcaagtatg aaaaattggt ggaaaaaagc aactgtctat caaatatatc caaaaagttt
     3481 caaagatagc aacaatgatg gtataggtga tataaatggt attatagaaa aattagatta
     3541 tctgtattct ttaggtgttg atttattatg gttgactcct atgtacgttt ctcctcaaag
     3601 agataatgga tatgatatag aagattatta taatatagac ccaaaatatg ggacaatgag
     3661 tgactttgaa aaactcttaa aagaagctca taaaagagac ataaaaataa tgatggatat
     3721 ggtcctaaac catacatcta ctgaacataa atggtttaaa gaatctaaaa aaagcaaaga
     3781 caatccatat cgtgattatt atttctggaa agatgctaaa cctgatggtt ctgttcctaa
     3841 taactggata tccagattta gtggaactgc ttggaaatat gatgaaacta ctaaccaata
     3901 ttatttacat ttatttgaag aaactcaagc tgatttaaat tgggaaaatg aaaaggttcg
     3961 tgaagaatgt tacaaagtac tagaattttg ggctgataaa ggtattgatg gttttcgttt
     4021 agatgtagtc aacctactct ccaaaacacc tggattacct gatgacccta taacagggcc
     4081 aaaaggagat ggaagaactc attacgctga tggtcctcgt atacacgaat atttacataa
     4141 tatgaatcaa aaagttttca aacctaaaaa tatagttact gtaggtgaaa tgtcatctac
     4201 tacacctgaa gagtgtatca actatactag agaaaatcga gaagaactat ctatggtttt
     4261 tagcttccat catatgaaaa cagattataa aggaggcgca aaatggacta atgaaatgtt
     4321 ctctctggat aaattaaaaa aagcacaatc tgactttcaa tataaaatgt atgaaggaaa
     4381 gggatggaat gctctatttt actctaatca cgaccaacct agagctttat ctcgatttgg
     4441 agatgataga ttttttcgtc aagaaagtgc taagatgtta gccataacac tatttggtct
     4501 acaaggtact acatacatat atcaaggtga agaaataggt atgacaaatg cctactttac
     4561 taaaatagat gaatatgatg atgctgaaag taagaatgca tactatcata tgattaaatc
     4621 tggtattgat gaaaaggagg cattgcttat acttcaacaa aaatccagag ataatgcccg
     4681 tactcctatg caatgggata atactattta taaggggttt tctaatcata aaccgtggtt
     4741 aaaagttaat aatgacaata ttagtgtaga aaatgagctt aatgattctc gttcagtatt
     4801 ttatacttat caaagattaa tcaaatatcg taaacaatat gatattttta cagaaggtac
     4861 ttatagattg ttagatgaaa atcataaaaa tctatttgtt tatgaaagag agtataaaaa
     4921 ccaaaatctt cttgttataa gtaattttac tcatgataat gtagtatata aattacctga
     4981 aacttatttg aataaattaa actacacaat acttgaaacc aattacacta gagatataat
     5041 tgaaaataaa atggaaataa aaccttacga aagtataatg atatattata aataaagtta
     5101 tttatgtaaa aattggtata acaccagggt gttataccaa ttttactaaa ttcaaaataa
     5161 catttataga atatctatag attacaataa ttatttgact tctacatcat tatatttctt
     5221 tgaatatact ttagtcatat agaaatatat aggaactaca attatcatcc cacctaatcc
     5281 ccaaactatc ttcataggtt catcaatacc tgcttttatc agtaataata tacttataat
     5341 aactgcaaat attggtataa ttgctcctcc aggtattcta aaatttacat ctttatcagc
     5401 atacttcttt ctcaatatta gtacagctaa acatgtagga atatattgaa taaatctaga
     5461 tacaacactt atttgagata atgttgtaaa tgaacccgac catgctatta gtaaagttcc
     5521 tatgacagat actataattg ctatataagg agctccattt ttattagttt ttcttataga
     5581 cttaggcatt aatccttgtt caaccaaagc agcagcagac cttggtgtaa atatggatga
     5641 tgcaatattt atacctccaa cagatactat agttcctatt gtaattatat acccacctat
     5701 aggacctagc atcttaatgg cagcatctgc aacaggagta gctgaccctg ccaagccatt
     5761 acccaacacc cctatactta ttcccagtat aagcatatat attactgata ctacaaacat
     5821 taccattacc aatgctttag gtacattttt cttagggttc tccatatctt ttgctgcaac
     5881 agctaaagat tcaaatcctg taaaagcata aaataaagtt atagatactg ctacaaaagc
     5941 tgatgacgca ctttgaccct tttgtattat tacaaatggg gtaaaattag aaccctttat
     6001 aaagaataat cctacagcta taaataaaac tattggtaat aattttccta tagtcatgat
     6061 attatttaag tgcttagatt gtttcattcc cataaaattt ataatcccaa gtcctacaac
     6121 taatatacca attattatat ttttagtaag tggttctgct gcttgtggcc atacagatga
     6181 tagtgttaca gcaaagaaat ttgccatagt agcccaagca atcatactaa ctatccactt
     6241 cataaatcca acttcaaatc caacaaaatc tccaaatgcc tcttttgcat aaagataggg
     6301 ccctccatca gtatcaaacc aactacctgc ttcagcaaaa cataaagcaa tagaaacagc
     6361 taaaagcata caaaaaacta atactaatat acttgctggg cctatatctg tataagcatc
     6421 accaggtaac ccgaatatac ctgaccctat gattgcattg attcctaata gtacaatact
     6481 ccaaaaacct aacttaatgc ctttttccat tgttattccc cccaaagcca acttaatata
     6541 tttatatttt ttatttagat gcttctttaa ctattgccat aaatattttt ttcatattat
     6601 cataatctct agtcatcatt tctggatgcc attgtatccc tattacaaac tcactccctt
     6661 ccttttctat agcttcaatt aaaccgtctt tagatgtagc tgaaacaata tatcccggtg
     6721 ctactttgtt gacaactaag tgatgaaaac tattaactaa aacttctttt tctcctaata
     6781 tttcatataa ttttgtcccc tcctttatct gtactgtatg tgtaggtaca ttagatagat
     6841 gttgctgatt gtgtttaata taagcacctt caattaaaga taaatcttga tacaaactac
     6901 ctccttcagt tacatttata atttgttctc ctctacatat acctaaaact ggttttttca
     6961 tatctaaagc atgttttaat aatttcatat caaaactatc tctctttggt gatattgccc
     7021 tcaacttatt atgaggttct tctttccata tgagtggatt tacatcttgt cccccagata
     7081 gtataagcgc atctatatta gatacctgct cctttataat ctcatcatca tatacaatcg
     7141 gtacaatata tggtatagct ttacacataa ctactgattg tatataatca ttatttacat
     7201 aagccctttc atagccagga aacattcctc cttcatcaat tagtaaatta cctgatattc
     7261 ctattattgg atatttcttt ttaaccaatt tcttcacccc ttaacttatt tgtgaacaat
     7321 aaaaaatgct acttctctta aagagcaagt agcataccaa gattttattt atttgaacat
     7381 tataattcat tttagaaata ctttttttga atacaagtaa tataaataac tttatttact
     7441 tatattttat tttaatcctg tttagtttga cttttttaaa ttgttttaag tacaactaat
     7501 aggtaaaata ggcatttaga ttttcctttt tatcaaccta ttaaatgctg tttaatatat
     7561 tttttcccct tctatttaat tcacttccct ttctaccaga ttcacatatt atcaaatcca
     7621 gctcttttaa catattaagt attcccctta cctcaccttc tgttatactg tagcctaatt
     7681 catttattga attaacaata ccatttctac ctatattttt attaagatta ttggcatttt
     7741 ttaaacactc cattactaac tttactttct ctatagatgt tctatccttt aatatgctta
     7801 tttctttact aaaatcttca gttatattta ataagttatg aggtaaatca tttattaaaa
     7861 taacatcctc agaactcata atgttaatat acatagcagt attttttaat tctcttatat
     7921 tacctggcca ttcatatgca ttaataatgt cttgaacatc ttgactaatt gctctcttcc
     7981 ttttcataaa atgctttaac ataacttcta tatcttcttt tcgctctctt aaaggtggta
     8041 tatttatggg caatacattt atcctatagt ataaatctgc tctaaatcta tctcctttta
     8101 tcatttctaa taaattttta tttgtagctg caattactct aacatctata tctattacat
     8161 tctctcctcc aactctcatt acttgattct cttgtaatac tctaagtaat ttgctttgta
     8221 agtatatagg catgtctcct atttcatcca aaaatatagt tccattgtta gcctgttcaa
     8281 ataatccttt tttacctcct tttaaagctc ctgtaaaagc accttcttca tatccaaaaa
     8341 gttcactttc aagtaaattt tctggcatag ctgcacagtt tatcgctata aatggctgac
     8401 tatgtcttgg tgatgcatta tgaatagatt gagccatgag ttcttttcct gttccacttt
     8461 ctcccgttat aagaattgta taatcagatt cagctatttt catacctaat ttcttagttc
     8521 tttccatctt cattgagact gtttttatat catcaaaagt atatctagca acttgtccct
     8581 tttctctaag cttctttgat aggttttgct ccaattttct tatgtaagtt atttcttgaa
     8641 tacaaaaata atacccagta acctttccaa aactctctat attatactta tttacgttta
     8701 agtacttatt attaaatttt ataacttcat catgtgcctt actcaaacta aaaatctttt
     8761 taatattctc attctctaat tcatctatat ttttccctat aatattactt tgaatatcta
     8821 gtatatccct taaactatta ttgcaaataa ttatgtttcc cttatctgat accattgcca
     8881 tacctaagtt tgataaattt attatagaat ttaattcatc tgcttttata gtaagttctt
     8941 tgtatttagt atttattcct gaatataaac taattatttc atctgtatac ttaattaacc
     9001 tctcagtaat ttctttatca tccagtttga gttttgctat tatttgaata aacgttgaac
     9061 tatcaatata cctatggcct aaatcaataa cttcttctat atattttgga actaaacttg
     9121 actctcctgg tgttatagct atcttaatat ttctatattc ttcattggga ttgtatggta
     9181 taaaattcag atgatttatt cctatattgt ataaattaga tattgtttcc aatacagtat
     9241 gcttattatc gtttactact aatacatcta tttcttctgg caatgaaaat aacttatata
     9301 tatccttttg ctttatgctc ctatttatag ttattatctt tgagacatct tctacatatt
     9361 tttttatttt taatactcta tcatctatca ttaccaatat tatgtcatct tttattaatt
     9421 ccttctctgt tattttattt aaataataat tttttatctt tactttatct ttaaatatca
     9481 tttctagatt tttatttaag aaacattcta atttagacaa cccatcagtt actactgcta
     9541 ttgttttcat ttgattactc ctttaaaaat atactctact cttttataat atacatctga
     9601 ttttcacttt aatagcacaa aaaattgtac atttagtata ctaacatatt cctttattag
     9661 ttttatgtcc ctaaatatca tagttgcaat atctatcata tttcttaaac ttctataaag
     9721 caaaaattgt gccaaattaa taattttctt aattttattc taaagttcct caatagtatt
     9781 tacagactta gcacttatag cttataagtc tttatattat taatctattt ttataggtta
     9841 attgtacaaa tcatatatca cttttaccta ttaaatgcat tataaaaaag atggaataac
     9901 gattcgtcac tccacctttt ttgtaataaa aaattgtata tataaacact atttactact
     9961 cttctaagta caaacagtat ctacatacta taacctttca ccattagatt ctattacttg
    10021 tttataccag tcaaaactct ttttcttaat cctagacaag tctccacttc catcatcata
    10081 cttatccacg tatataaacc catatctctt ggccatctca ccagtagatg cacttactaa
    10141 atctatacat ccccatggag tatatccaaa taaatcaaca ccatcttcta cagcttcctt
    10201 catttgctct atatgtgctt ttaaatactc tatacggtag tcatcattta tcactccatt
    10261 agattctttt ttatcataag ctcctaaacc attttcaact accatcatag gtattctata
    10321 tctatcataa atttcattta gtgcatatct aagcccttca gggtctattt gccatcccca
    10381 ttcactagac ttaagatatg gatttttcac tccacctaat atgttgccac ttgtattatc
    10441 ttctttagaa tcactactta cacatgtaga catataataa ctaaatgtat aaaaatctac
    10501 acaaccttct tttaaaattt ctaaatctcc tttttccatt tttatttcaa tattattttc
    10561 tccaaaatat ctattcatat aagttggata ttcgccacgc acttgtacat ctccacagaa
    10621 ataattcatt actctactat ctctttgagt tttaactgca tcatctggat tacaagtata
    10681 aggatacatt gttgcaaata tttgcataca tccaacttga taatttgaat ctatttcatg
    10741 agctaactta acagccttag cacttgctac aaattgatga tgtaaccctt gaaaacgaag
    10801 ttgaggtata tctacttggt ttataaaatc tgtagtccct tcatttaata ttccttgtga
    10861 taagtagcct cccataggca ttgtagctga atttatttca ttaaatgtca gccaatattt
    10921 tacttttcct ttatatcttt taaatattgt ttcacagtaa ttcatataca agtctattac
    10981 ctctcttgaa acccatccat tgtatttctc tgttattgca aatggtattt catagtgaga
    11041 tattgttatt aatggttcta tattatattt taaacattca tctatcacat tttcataaaa
    11101 tttaagtcct gcttcatttg gttctttctc cattccagtt ggaaatattc tagtccatgc
    11161 tattgaaaat ctaaatacct taaatcccat ttctgcaaat aaagctatat cttctttgta
    11221 tctgtgataa aaatctattg cttcatgact tggatagaat gttccttttt ctataactct
    11281 cgttattctt ttacttactt tttgagaacc tccagtacac atatctgaac aagaaggacc
    11341 tttcccatct aaattccatg ctccttcaca ttgatttgct gctgttgctc caccccataa
    11401 aaaatctttt ctaagtacca ttactctacc tccaataatt tatttatagt aaatttattt
    11461 taaaataaaa atacatatat ctaattttta attaataaaa ctctctttta agctaaaaca
    11521 gttatcaatt cctgactatt atttacatgc ttttgtgtat tttctataat atccacataa
    11581 tcagaataat tagtaacaac tactggtgtt tctaagcaat atccttcttt tgatatgctt
    11641 tctatatcaa aagttattaa tgtctgacct tttttaatct tatccccttg attaacaaaa
    11701 gatttgaaat gtttaccttc caactgaata gtatttaacc ctatatgtat caatagttca
    11761 caaccattat cagatataat tcctattgca tgttttgttg gaaataaagt cattatagtc
    11821 ccatcaaatg gtgccactac ttttccttct ttaggtgtta ttgctacacc ttttcccaat
    11881 atacctgttg aaaacgctgc atcttgtatc tgctccaaag cctttacttc accttttatt
    11941 gggctatata ctacttctct tttgtttttt tctacaacgc cttgcccatt attatcttta
    12001 gaaatttcta ctatagaatc atctttccaa aaaaataatg ttaaaacaaa tcctactaca
    12061 atagctacta ttattgctat tatagttgca taaacacctt tcatatctcc agttgttgga
    12121 tttatataat taggtatacc aaatattcca agtccaccca ttacataatt ttttacattc
    12181 attatcccca ttacagctcc tgccacagca ccacctatac aactatatat gaatggtgtt
    12241 tttcttggta aagttattcc atatattgca ggctctgtta caccacatat ccctgaaata
    12301 actgcaggta tacacagctc ttttatcttc ttatctttta atttaaagta cattgctgct
    12361 actactgatg tttgtgcaaa agatggtaca aatgctccca ctaatattgt gtcaaacccc
    12421 atagtcataa ggtttgacat agctattggt actaatcccc aatgtagacc aaatattaca
    12481 agcacttgcc acaataaacc agttaataca ccacttaaaa ttggtgaaaa gttaaataaa
    12541 gctaaaaatc catttccaac tatattagaa gcataggtag ctataggccc tataaccata
    12601 aatcccaatg gtaaagaaac taataaaact gccattggta caaagaaatt ctttactaca
    12661 tctggtatta ttttagcaaa cactttctcc aacttagctg ctaataatac tattataatt
    12721 actggtacta ctgttgaagt gtagttcatt gctattactg gtaatcctaa gaaagttata
    12781 tatactggtg attcaaatat tgttccagta aatagattgt ataaaggttg acctatagat
    12841 gctagagtat ctaattgaat acctgaatag cataaaactg cacctataag cattccaata
    12901 aatggtttta atttgaattt cttagcagct gtatatccaa gaattattgg catatactgg
    12961 aacattgcat ctccgattgc atttaacata atatatgcac catcagtttc tccatacaaa
    13021 cccaatgctg taaatactgc attaaatcct tttatcatac cagcagcaca cagaactcct
    13081 aatattggtt gaaaaactcc tgatattatg tctataaact tattaagtaa tccttttggc
    13141 gcatctgagt ctgaattatc tattgtatct cctcctaatc cagccaaatc gcacacaact
    13201 tcataaacat ctggaacatg attaccaata actacttggt attgacctgc acttttcatt
    13261 acagtaacta taccatccat tttttttagc acatcatcat ttgctattga ttcatctttt
    13321 aatttaaaac gtagcctcgt tatacagtga gataaactgc taatattatc cttccctcct
    13381 acattctcaa tgatttcttt tgatagttgt tcataccttc tcattttttc tcctccattt
    13441 tctttttgaa atatgaaggt ttggccaact taatgtcacc acccaatata tataaaccta
    13501 attattagga tttatatctg acttaatact tttacttacc actctttcaa cgtgaatagt
    13561 taagtataat ttttcctcat ctgttaaatc gtagttgtat tttttatgta taaattcatc
    13621 caacttttct atgcatttat aagcattttt atatttaact tttattacat ttagtaaatc
    13681 atcttcatta ttttcatgta aattattact aacaattcgt tctgcaaaat actttaagtg
    13741 agtaataaat ctatgatagt aaactgaatc ttcatcaaat actattctgt aatggtattt
    13801 aaccatattt gaaatttctt gtattattcg tgtaatctca tatatagttt ttatactttg
    13861 atccatttgt gcattaacta tatgcagtgc tataaatcca gcttcatctt ctgatagtct
    13921 aatttcaaat tttttttcta tataatccaa tgcctctaac cctattttaa attcactctt
    13981 ataaaatctt tttatatccc aaagtaatac attttttaca cttactcctt cacgagctct
    14041 ttctattgca gtatacatat ggtctgttaa agaaatataa atactatcat ttaatctttt
    14101 ccctagtttt tctttagcat ataaaattat ttcatctgat aattccatat atcttatagg
    14161 aatatctgct attagttctt taaatttatc agatatattt gggtctgaaa gtttgaatat
    14221 cttatcaatt ttatcctttg atatatgctc tcctgtacgt tttttataag ctaaacctct
    14281 ccccataact actatttcct tatgattttc atcagttgta ataattacat tattattgag
    14341 tattttttca ataatcattg tgatgccccc tttattagca ttaagttaaa ataaatcttt
    14401 tttaattatt tagaatattt aaaatgtaat ttattacata aaaaaaacct atttattaca
    14461 cattaaatag actcccatga gtcctgagta ataaataggt ttagcttgta tttaaacaat
    14521 cactatccgt ttgtatttta ttttaattat tatttattat atgttagcaa atttattttt
    14581 tagtgtcaac tttttctcaa tattttaatt ctaaataaat tatataaatt gaatcttcaa
    14641 agtactattt ttataaataa acaaaataaa aaaggtatta ctttctttaa gtaataccca
    14701 tttattttta atttaagtgg tttttcttaa tctcatcaag tagtccatct tctaaataaa
    14761 tttctaatgc acatcctacc attgccttta ctgctttgtg aagtttatca taagcttcct
    14821 cagaatttgc ataatttaga aattcttttt catgaacata taccattgga cttatatcta
    14881 aggctatttc tgtatacata gtagggcaaa cttgacttac attacctata tctgtagaac
    14941 ctactggacc atctttacct tctaatatat ctgttatacc tgcctcaatc aaattattct
    15001 ttgttatctt ttgaagtact ttgttattta ttatgttgtc aaaagaattt tcaaagtatc
    15061 tataagaaag cttagctcct gtcattaact ctgcaccttt tgcacagttt ataacttttt
    15121 tagtcacttc atctaaataa cttctttcag cagctcttac aaaaaactta caagctgctt
    15181 tttctggaac tatatttgga gcctctcctc catttgaaac tattccatgt attctaacat
    15241 ctgattttac atgttgtctt agtgcattta tcccagcaaa agtaagttgt actgcatcta
    15301 gtgcattaac tcccatatga gggtgactag ctgcatgtgc tgatacccct tcaaaactaa
    15361 actctaatga atctattgcc aaagccttac agtttatatt attaaaagct tctatatgca
    15421 tttgataact tacatcaaca tcatcaaaag ctcctgcctt aactaaatca cattttcctc
    15481 ctgttgtttc ttcagctggt gttcctatta gtacaatttt tcctttaaaa ttttctttta
    15541 acttacttaa tactatacaa gctcctagtg tagatgctgc aatccagtta tgcccacaag
    15601 catgagctgg ttctttattg tctccatatc caggaagtgc atcatactca gctaaaaatg
    15661 ctatggtagg cccatcatta tctcctaatt cagctctaaa agcagtctcc atattacaat
    15721 atggataaac tgtatcaaat ccatattcct tcattttctt tactaagtat tttgatgata
    15781 tgtattcttc ttcccctaat tctggattgt taaatataaa attacaaact tcttcaattt
    15841 cttttccaag ttcattctct atctcataag ctctcttctt tatactctct atcataactt
    15901 acctcccact agaatcctag atataatcct attgtcaaaa ataccattac aagaattgtt
    15961 aatactacca ttaaaggaat tacgaatcta acccactttg accaaggaat attggctact
    16021 gctagtgctc ccattaaaac acctgatgta ggtgttatta agttagttac acctatacca
    16081 aattgataag ctgtaactat catttgtctt gatacatcta ctaagtcgcc aagtggtgca
    16141 agtacaggta ttgtaagtga tgcaagccct gatgctgatg gtattaaaaa tgctattaat
    16201 ccttctatta agaaagttaa atttataaat atagtttttg gtaatccatt taataaattt
    16261 gctgcagaat ttaaaattgt atctattata aatccatttt ctgctattat tacgattcca
    16321 cgtgcaaatg ctatacataa ccctgctgta attaaatctc ctgctccact tataaatgaa
    16381 ttaactatct catcttgttt aagccctgat gctattcctg atattatacc tatagctgta
    16441 aatatcattg caatttcagt tatgtaccac tctagtctta aaactccata tatcataatc
    16501 gccataccta ttgtgaaaat ggctattacc atggcttctc tttttgtaaa ttcctttata
    16561 tttgtatcac tattaaccat tgattcttga tttagtgata tatcgtgtac taaagatttt
    16621 ttagggtctt ttttaacttt attggcatac atcataacaa atcctataga tatagccata
    16681 tatattataa acataacaac tctaaactct attccagaac ctggtactat ttgtgataat
    16741 gcttgtgcta ttcctacaga gaaaggattc gtagtagctg ctccaaatcc agctgttgct
    16801 cctataaata ctgtggccac tgctgtcaat gaatcatatc ccatactggt cataagtgga
    16861 ataaatatca tataaaaagg tagtgtctct tcactcattc caaacgtcgt cccacctagt
    16921 ccaaatagaa tcattgaaat cggtattatt aaaaattgaa acttcttcat tttatttaca
    16981 gtatgagcta taacagcttc tatagcccct gttttattaa ctatcccaaa agctcctcca
    17041 actattaaaa caaatccaac tacttcagct gcatctataa atccgtttat aggtgctgta
    17101 aatacatcag taattccttg tggatttgat ggtgcttttt cataagttcc agctacaaca
    17161 actgaccttc cgtctatatc tactctttca aaatttccac ttggcactat ccaagtaaga
    17221 attgccatta acactattag caaaaatatt attgtaagtg tctgtggcat agtaaacttt
    17281 ttctttttta aactgctcat ttttaatctc cccacttttt aaattaaata ttttattatt
    17341 gcatcccttt atcctatttt gtatagatgt aaaaaagctc aacatggata catgttgagc
    17401 taaatgtgct aaatacaaca tacctgcatc ttccctttat cttgtttaag atagctctcc
    17461 atcaaaattc gggataattt tgatgacagt actgtaccta ttaaatacag tcccagcact
    17521 agctttggac actagcactt cggcacttac tccttttata ttgcctcatt ggtttccaac
    17581 ctcttcaata ttaatcttag taaatgcaac ctctacctca atctgttcgt tagatgaggt
    17641 aattcttatt aatttttatt gattcaaagt aattgtagca taatatgtcg agattgtaaa
    17701 tattttcagt ataataattc ttactttatg atgtcattcc atttttcaca aataattttt
    17761 tctccatata atttaaatac tgtagtatat tttaaataca cacaaacttt ccacaaattt
    17821 aaaattatta taataccttt ataataaaaa ataaaagcca tgtaaactta tcaatttaca
    17881 cagctttata tacattaatc tactccaagt acagctttaa gctttgatgc tattgtaata
    17941 actcgtggac caaatataac ttgaactgag tttttctttt taacaactcc acttgcaccc
    18001 aattcattta cccagaaacc atcttcatag aatccatcaa ttgaatttag ctctacccta
    18061 agtctagttg cacagtttgt aacatttttt atattattac ttcctcctaa accttctatt
    18121 atagaatgta caagctttgt atctttatca tctacttcct cttctactgc attgttgtat
    18181 gctgttttac cagcatctac agattgtctt tctctatatt ctttcttact ataaagctta
    18241 acttcttctg aacttcttcc tggtgttttt atatcaaact tcttaattgc ccatgtaaat
    18301 attatataag taactataaa aaatattggt atcaaaaata ataatggtaa cgcatccact
    18361 ttttgtggtt gtaataaatt aggaaacata tttctaaatg attctcccat tatagaaaca
    18421 ttaaacattt ctgtaaatac atatgtcaat cctgccagtg gtacatatgc tacaaaatac
    18481 aataatggtg caacaaatag gaatgtatac tctattggtt ccgttacccc taccaacatg
    18541 gctgttacta ttgctggtat caatatactt attgcttttt tcttattagc attatcagcc
    18601 aacttataca tagctaaagc tgctgctggt aatattgcaa aatgtattaa taaacgacct
    18661 gttgtgaagt tacgagttat ataagatagt gtatctgggt ctcccatttg agctaatctt
    18721 atattattaa caccctcgta aattgctcca cctacttcca ttgttccacc tactcttgta
    18781 tattctatag ggaatgcaat taagtgatgt ataccaaatg gtaataatgc tttatccatt
    18841 gctccaaaag taaatgttcc taataatcca ctagaaccta tccaattacc aagtttagat
    18901 aatgccaacc ctactggtgg ccatataaag tacattgctg tacccaatac tattgatgct
    18961 ataaacatca taatcattga aaatcttgga cctgagaaaa aagataatgc actaggaagt
    19021 tctatgtcaa caaatttgtt atgtactgca ctagctacaa atccagctat tatagctcca
    19081 aatatactac aatcatatga aaagattcct aagaaagaac catataaaga acttcgacta
    19141 tatgcttctg cctctcctaa tccagatgcc ataaacgctt ctgctgtaac tgtatctgaa
    19201 tttataccat ttgatgctaa caatgtactt ataactgtgt gcattcctat aaataaaaca
    19261 attcctccta atgcacccca tcctttttcc tttttagata atccaaaagc tatacctgta
    19321 acaaagaata ttggtaagta tctcattacc ataaatccta aatcgtttat tactttaaag
    19381 aatacattta taaatgaccc ttcttttatt agtccgctaa gccctaatgc agaaacgttt
    19441 tccatatttg caaaagctga ccctaatcct ataaatactc ctgctacaac aagtaatata
    19501 acaggtatca tcattgctcc agaaagtact tgtaatttat ccttcatagt attatttcct
    19561 ccatttttat tgaaatgcca ggctatataa tgcatatata tatacttcta ttgctttgta
    19621 taatgtatct atacttatat tttcatttgc ctgatgtgaa tttggattat ctccctctat
    19681 tgtgggtcca aatgcaactc cattttttaa cactcttgca taagatgcag ctccttttgt
    19741 aaaaagttcg gcttcttttc caaaaccttg tttatatgca cttgataatt tatttattaa
    19801 ttcactatct ggttttacat acagtaattt taaatcctta tatatatcaa ctattaaatt
    19861 ttcttttttt ccaatttcat taattctatt agttataaac tcccaactta tacccttagg
    19921 atatctaaag tctattttca tattcaattc atttttctct aagaagatac tcattataca
    19981 tattgtagaa actcccatat ctacatcttc tttatatatc cctaattttt ttccatgatt
    20041 atcatctgta aagtatgaat ttaaaatatc ccttattata acgcctttat catttagttt
    20101 tttaattttc tctaaatctt ttgctaaact aaatgcacag ttatatgacc tgtgtggatt
    20161 tctcgataaa gctctttctc ctgtatatct tactaatact ttaccttcat ctaattcttc
    20221 tatctctgta taataagcta atgattctac taaatctttc ttatcatcag ttttaaaaac
    20281 agcctcaatt ttgtcacata caaatccatc ttctttgttt gactttatat caactaaatt
    20341 gtgatttcta aatttatctt tatctatttt ctttcttaga ttgaagtata aaataccttt
    20401 ttctccattt actattggga agtttccatc tggagaaaat gcaaattttg gctgttcatt
    20461 gacactaaag taatgctcca tacattccca agtcgtctct tcagctccac ccactatcaa
    20521 tctaatcttt ctcttcggct tttcattaag ttctcttaag aaaagtaatg catataaaat
    20581 ccctatcaaa ggtcctttgt tgtcattaac tcctctacca taaagatagt tatctttttg
    20641 acatacttta aaaggtttac tcttccaaag ttctttatta tatattggca ccacatctat
    20701 atgattaagc acccctacta cttcgtctcc ttctccatat tctatatgaa ttgcatatcc
    20761 atcaaagtct tttacaacaa aatctttgtc ttttgctatt tgaataagct tatcgaaggc
    20821 atttcttatt tttatcccaa atggttgatt tatatctgtt gtactttcat ctctaattga
    20881 aggtatttca actaaacttc taatatcatt tatgatattt tcttgattgg attttaaata
    20941 atcaataatt agttctttgt ttactatcat cttaattatt tatcacccct ttatattaat
    21001 tttacaaagc atttcagttc atatctacat tataaatttt gaatattatt ttttcaatat
    21061 ttcaaatact tctctaagtt accataatga tacggtaaac aatcaacaga ttatgacaaa
    21121 atcatactat acctattact aatattttaa cttatctatt acgtcttttt taatgtaagt
    21181 ttattccaaa aatacataaa aaaagatgta gccttagcta catcttctta tatctattca
    21241 acttccatta ttatgctatt aatatctaca tttccaggtt ctatcctatc ttttactgtt
    21301 ctcttaacag aatcagcatc atccattata actacaggag ttattatatt taaatcattt
    21361 gacgttataa aatctaaatc tacttccatt attaaatctt tagcttttac cttatctcct
    21421 gcctttacct taacatcaaa cggctttcct tctagtgaca ttgtctctaa acctacatgt
    21481 attaatatat ttgtattatc attactctta atcattattg catgctttgt atcaaataca
    21541 ttgactattt caccatcaac aggagaatat aacttacctt cacttggtat tattgctact
    21601 ccatctccca tcatcttttg ggcaaaaact gcatctggaa catcttctaa gttcactaaa
    21661 tttcccttaa aagggctata tattttctca atcttatttt cttttttctt aaatatatta
    21721 aacataacac actctccaca ttataaaatt ttatgataat atttttctta aagcttttgc
    21781 tacaccatca tttacattag tatcagttac aaaatctgcc atagatttta cttcatctgt
    21841 agcatttccc atagcaatac caagacctgc aaatttaatc atggatatat cattttcatt
    21901 atcacctata caaataactt ctttgctatc tatacctaat atatcacaaa attttttaac
    21961 tgcaatacct tttgaagtac ctttgctcat aacttcaaaa tttatctttc cagaacttac
    22021 tacttctaaa tcttcttgtt ttttaaattc ttcctttgct tctctcaaag aatctacgtt
    22081 ttctgagaaa agtatacatt ttaaaatttc attatcagct ttttctaata aagtttcaca
    22141 acttgcattt tctattattt caattctgtc ttcttcttta tttttactat ttattaatct
    22201 atatggatgt tcttcaccta tttcattgtt ggatataact attttacagc ctttaaaatg
    22261 tttgtttaaa ttatactttt cacctattgt atagattttc tttagagctt ctttgctcaa
    22321 aaccttctta tactcatatc ccagtaattt aaaatatgtc ccattagttg atataatata
    22381 tatatcatcc cctaaaacac ttgtaaaata tttcatagca ttataaggtc ttcccgtaac
    22441 taaggctacc ttgataccct tttccatagc ttcttttagt gctttaatat tttcttctga
    22501 tacttcaaat cctttaccca tcaaagtacc atccatatca gtacaaatta atttatatcg
    22561 catttgtatc acatcctagt aagatttttc taatatttca acaaggtctt ctttctttcc
    22621 aaaaggtaaa aatcctaaaa ctggacagct tgttatttgt tctaattgtt cctttgttac
    22681 attaaactca gacatttttg tcttaagtcc cactctcttt aaaaaacttt ctatttcatt
    22741 tcctaaagtt ttagctgctt catcatcttc cactttttct aattcttggt ttagcattct
    22801 cgctactttg gcaaatttct ctatattatc cttatagaac ttttctgcaa attttgggaa
    22861 cactatagcc aaagcctcac catgaggaat atgtgtaact cctcctatta tttcacttag
    22921 tggatgtggt gctgctgctc cagcatttgc cagtgaactt cctcctaatg tatctgctac
    22981 tgctaacttt gttctgtatt ctatattatt tttatcttcc attactttag gtagatagtt
    23041 aatgactaat tccatagatt tttcagacat tatctctgta aagtcattag catttggatt
    23101 tatataactt tcaaatgcat gagtaaaagc atcaaatgct gttgatgcag taattctctc
    23161 tggcagagtt aacataagct ctgggtcaac tatacattct tttgagaaac aattttgatg
    23221 aaatattgta tttttctcgc ttcctctcga tattactgct gcttgtgtaa cttggcttcc
    23281 tgttccagaa gtagttgata cagctattaa tggtaattct ttttcactta ccttatcgta
    23341 tattttaaat ggatttgtat atgtactaaa catataatcc caatctattt tttctaaacc
    23401 aaaagtcaat gctaatactt ttgcagtatc tatacttgaa cctcctccaa cagctaaaac
    23461 aacatctaca gattcttttt tagctaattc gaacccttca tttattaatt ctacagttgg
    23521 gtttggctct actctatcaa agtgtacaac ttctatacct ttttctatta aattcaatgt
    23581 aactctttta tataacttgt ctaatggctc tacatttgga gtagtaacta acaaacattt
    23641 ctttccatat tttcctatta ttctaggtag ttcacttaaa gttccttgtc caaaatttat
    23701 tcttgatggt tgataaaagt taatcatatt tttcctccct taaattattg acttcatatt
    23761 caaattatac atatcatagg atttttaagg caataccttc actgttaact cttatttact
    23821 aaagcttatg gcaattatta gacaataaat gttttattat taccatatca ttatgtaaat
    23881 tttattaagt acccatgtta taattttata atcaatctta ttgtataatt gacttaataa
    23941 taaaaataga gtatatacac ttttttatga caaatagctt aaaggagaat taaattatga
    24001 aatatttgat agacagtgct aatcttgatg aaattcaaaa gtgtttaaag tatggattta
    24061 agggaataac agctaatcca tctatgtatc ttaaagagaa ggtaaacttc catgaattta
    24121 ttgagacatg tactaattta aatccagaaa tattaactgc tgaagtcatt ggaaataatt
    24181 tatacgaatt aattaattca tgtgataaga tattaaatat aaataaaaac actataataa
    24241 aaataaattt ctctgaagtt ggcttagaac ttataaacat attaaatagt aaaggtgtaa
    24301 aaactgcatg taccttgatt ttcaatgtaa atcaagcatc attagctata aatgcaggtg
    24361 ctgattacct attccctttt ataggtagaa atgatgaaaa tgggaatgat ggtataaaaa
    24421 accttacaga aatatgtaac cttatatcaa taaatggata taatactaaa gttgttgcag
    24481 cttctattaa aaatgtattc cacttaactc aagcatctct ttgtggatgt gattatgcag
    24541 ctgtaacata tgatttattt aaaaaagctt cttttaacca gcttacagta gatggtgcca
    24601 atacttttga aagagattgg tccaaggtta ataaatagta actaagattt aggagggttt
    24661 gcattgaaca aaagattatt agatattgct gaattattac tcaacagctc agactatatt
    24721 actgtagata ctattgccga agaattaaaa gttagtaata aaactattcg taatgacctt
    24781 gttattttag atgaatggct tttagagttt aatttatccc tagataaaaa aactggttca
    24841 ggggttatta ttctaggtaa tgaagatata aaacttaaag ttattagaga tatcaatgat
    24901 aaatcaaatt gtatatatgc atactctcct gaagatagaa aaaggtatat tctaagtaaa
    24961 ttatttatta aaaattctaa gtttaggatt cgtgatattt gcaatgaact acatgttagt
    25021 agagctactg ttcataaaga cttggtagtt attcaaaatt ttttgcaaaa ctttaaagtg
    25081 actctagtta gaaaaaccaa taatggagta tatttagagg gaaaagagaa agatattcga
    25141 aaagcaattt ttgaacttgc tactgttaat aaaagttata ctgaacttaa agaaatatta
    25201 ttctcgaact ctaatgaatg caaagatacc ccatcaacaa aaatatttaa ggagctattt
    25261 aactatgatt ttgagaaatt atctcaaatc actctacaca ccttacaagt agaaaaaagt
    25321 aaccttagtg atgagtatta tataaacttc ttaatacata tagctatatg tattaagaga
    25381 atttcaatta aaagatatat taacttatct gaaggttttt ttagagaatt attagaacat
    25441 gaatactttg aaaaatcaaa aattttatgt gctaacctaa gtgaagcttt tgacgtagaa
    25501 tttattgatg aagaggtctg ttatatactt cttcatatag aaggattact taaatcaata
    25561 aagaaaacta ctactcttga acctcttaaa aatgaagaaa ttacagagta taatctatct
    25621 gaagcaatag ctgttcattg gggaagtata ctaaatttaa acttaaagga tgatttaata
    25681 ttaataaagt ctcttgctaa tcaccttaaa tcagttctac acagaataaa ctatggattt
    25741 actattacaa atcccatatt aaatgatata aagagaacat ttccttatac ttataaggct
    25801 gctaaagagt ctaatactgt tatcaaacag ttgatgaatt atgaagtcaa tgatgacgaa
    25861 ataggatatc ttgctttata tttaatatca gcaatagata gaagcaaatc tcccctaaat
    25921 actattttaa tatgtcactg tagtgatggt gtatctaatt tattagtcca aaagttaagt
    25981 tttgaattta atcagattaa tatagttaaa tctatacctc tatcttctat ttcatttacg
    26041 aactttgatg atgtggactt aatactaacc actgctcctg tagactttga acataatgct
    26101 gaactgataa atataaatgc tcttttaagt aagaatgata tttccagact tagtacaatt
    26161 ataaaaaaac tatattctga aaaaaataaa atattatctt ataaataaac aaaaataggc
    26221 ttgtctcaac atagagataa acctattttt cattgtccaa atgataaaaa tatatttgat
    26281 ttcatagaaa aagtgcctca tgaactaaaa aattcatttt gagacacctt cattttttat
    26341 atttaatctt tttatttaag cttttatatt ttttaaactt ttatatttaa agtaaatttt
    26401 attattttta ttgagcgcaa gcattattta tattattaat ttcttcagta ttcttaccaa
    26461 actttgtagt tacaaatcct attgttttta ttatgagtaa taaggatatc aatgaatata
    26521 tagatatcat aaaattctta cttattattc cagatgctac tattataaat ccatctagca
    26581 taaataatat aactggcaac ttcagaaact taattacctt attaataagc attgcaacta
    26641 aatcagttcc accagtacta cagcccctta ttattgctat ccctatagca gttcctacca
    26701 ataacccacc tatcactcct gctactaata gattgtcagt tatgtgagtt tgtggtatta
    26761 cttttaagaa taatggaccc ataagagtta tatataatgt ttttattcca aaacctttcc
    26821 ctaaaaataa taatcccatt actaaaagtg gcatagatat tcctaatgat atattctcaa
    26881 caggcattga taagaatgtg ctaagtacga ctgataatcc tgttatccct cctggagcta
    26941 atgtatgttc tgcaaagaaa aaattaactg ctaatgccat taaaaatgct gatattgtta
    27001 tcagtaaata atcttttatc atttcttttt tcatttaata acctcctatg attatattgt
    27061 ttcagtataa aaaatcaatt aaattagtct agcttcctgt agtttttcat aaaattaatg
    27121 cttccttaaa acattaagaa agcatctctt ttatcatagt ttattatctt attctaaacc
    27181 aaactttgta gctgcttcat ctatagcttt tctacaattc ttaacacctg ctgttatacc
    27241 atctttatcc ttgaatattg ctgaagataa tattacaacg tctggattac attctattaa
    27301 tggctccata ttgtctgctc ttagtccacc atctattgct aattcacact taggattctt
    27361 ttcgtctatc atttttctag ctctttttac taaatcaaca gcactctttc tccatcccca
    27421 gttatctttt ccatcagttt catcaacacc atgaacgact atttgcaatc tatctatatc
    27481 atatatagct tcatcaacaa aacatagtgg tgtgtaacat ccaattgtta atcctacttt
    27541 cataccaaat tctctacagt aatttattat gtatgcaaga ggagcaccta aaaaatgttc
    27601 tgctggtatt atcaacaagt tacatcctgc tgctgctatt ttttctataa ataatctatc
    27661 acaatctctt gtgtatatat ggcattctat tggtttatct gtcactggtc ttattgcttc
    27721 tattatttga tgaccaccca taagttgcat attttttaag tcatgcatat ctgctgcatc
    27781 tgaatgtacg tagtctacac ctgcatccat tgcttcttta actacggctg atatatgacc
    27841 gtaatttaca tgtgctaatc ctgctgctat ttttatgtgt ttcatatttg tatacctcca
    27901 tattttactt taattagtat taaatattag tttttgatat tttttaatcc agtattactt
    27961 ttatttagca ttacttttat tgctgtatat atttctttta tgaacttatt ctgcttttgt
    28021 caactgtgaa cttattttgc tttgtaaatt aatattacac tgatatattt tttttcacaa
    28081 cactttgact actccttaaa agtaccttta tattgtggta aattatagac attaattgta
    28141 tataaaaagt tagtttttta ccacattctt atggcattta ttgtctatac taactcaatt
    28201 gatatagcta gttcatttaa tatataatca gactataaat ataaatttac tcgataaaaa
    28261 gtaccattca taacaatatt aatgaaaggg agatgtaaaa tgagaaactg tattattgcc
    28321 caatctggag gccctacagc tgttatcaat gcttctgcag ttggtattta tgaaaaaaat
    28381 ttagaaacta aatactttga taaagtatat tttggtatca atgggattga aggtatatta
    28441 aacaaaaata taatagattc agactcctta aacaaagata atgtattaaa tttaaagcaa
    28501 acaccttcgt ctggtcttgg ttcttgtaga tacaaactgg ctgattataa aataaattct
    28561 tatgattatg atagagttat aaatatacta gatgaatatg aaatagatac attattttat
    28621 ataggcggaa atgattctat ggacacagtg atgaaatttt ctcaatactg caaaaacact
    28681 acttgtaaaa taaaatttat agggattcct aaaacaatag ataatgattt attaggaact
    28741 gacaactgtc ctggatttgg ttctgctgca aagcttattt ctacactaat aatggaaaca
    28801 tacttagatt tttctatata caaaaataat ggtatattta tagtagaaac tatgggtaga
    28861 gatactggat ggttagcagc ttcttcttca ctagctagac ttaatgatac tccacttgtt
    28921 gatttaatat accttccaga aattgatttc tatgaagata agtttataga agatgttaga
    28981 aaaatattta aagaaaaaaa taaggcttat atagttgcat cagaaggtat aagggataaa
    29041 tacggcaact ttatatgcga acaaaaaact tctgctcatg ataaatttgg tcattcccaa
    29101 ttaggtggag taagcaacta tctaaagaat cttatagtat catcatcaat tacaacaaga
    29161 gtaaaaacct tagaacttgg tgtaatacaa agatgtgcta tgcatttagc ttcagatact
    29221 gatttaaaac aagcagctga agttggtgca tatgggatag aactatctaa aaaaggatat
    29281 acaggagtta tggctatcat taatagaaca tgcaataatc cttataagta tgaagttagt
    29341 catactgata tttctaaaat agctaacaag acaaaatatt ttcctaaaga gtggataaat
    29401 gaagaatata attatataac tgatgaagcc ctaaattatc tatatccact tattcaaggt
    29461 aaaccagata tcaaatataa aaatggacta ccttattttt caattattta ctaggaaatt
    29521 attataattt gatatacact caattctatc gctcttaaat acctaagtgg ctgttaaata
    29581 aaattataaa ttgttatatg acagtcactt aatcgtttaa ttatttaact gtttagtttt
    29641 ttaatttttt aatctttttt aatactaata cgatttgttg taataatatc tcacacccat
    29701 tttcattttg gatagattat aattagttag acaataaata ttttgtcatg atattattat
    29761 atatagtgat acaaatagaa atacttttat catgactaga aaaacaaaga ttacacaaag
    29821 gatttaaaaa tcaaacaact tcaattaaaa taaatggtta aaataacttc taaatcaact
    29881 acataaacaa taaaagaaca taaagtagtt aaatctacaa ttataaaatt agtaagacta
    29941 taataactta aataaaatta aagttaacaa agactattaa agttagcaaa tattcctcta
    30001 cctaaataat tgctttttat aaagagttat ttattttaat ttattttaat tgaaatacga
    30061 ttttaactag aacaatagat taatgtaata tttaatataa aataattata ataattgaaa
    30121 aggaagtaat ctatgatgaa aatagcagtc ataacaaccg aatttttaaa agagtttgta
    30181 gataattcta taaaaaagtt aaatattaat gcagaaattg aaatatatat ctatagagat
    30241 ttttctcatg ttggagattt atatttagaa atagaagata ggtttgatgg atttgcagtt
    30301 agtggcccca tccccaaaaa agctattaca aaaaaggctg gaactattaa aaaacctcta
//
LOCUS       DACTZW010000044        30254 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.044, whole genome shotgun sequence.
ACCESSION   DACTZW010000044 DACTZW010000000
VERSION     DACTZW010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30254
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.044"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            82..900
                     /gene="larE"
                     /locus_tag="JAM15_10805"
     CDS             82..900
                     /gene="larE"
                     /locus_tag="JAM15_10805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent sacrificial sulfur transferase
                     LarE"
                     /protein_id="HAT6798743.1"
                     /translation="MEVNFVKEKEKLDKLKKMLLELGSVVVAYSGGVDSNFLLKVAKD
                     TLGENVIAVTIHAMMHSSREIEEAKQYTQNFGVKHIILNIENFDLKEFKENGVDRCYH
                     CKKYIFSKIKEVAKEHNIKYIVDGTNIDDLGDYRPGLKALSELGVISPLKDSSLKKEE
                     IRSLSKTLGLNTFNKPSFACLASRIPYGVEITDENLRIVEKSEEYLSNLGFSQFRVRM
                     HGDIARIEVGQEELGKFFENNNFNKVDTKLKIFGFKYVTLDMSGYKMGSMNLNV"
     gene            955..2103
                     /locus_tag="JAM15_10810"
     CDS             955..2103
                     /locus_tag="JAM15_10810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HAT6798744.1"
                     /translation="MKNYTLISPCFFGMEKMLAREITNLGYEIIKTEDGRITYKTDEF
                     GIAKSNMWLRCAERVHLKIAEFEAKSFDELFENTKRINWSRYIPYGAQFPISKASSIK
                     SKLYSTPDVQAIVKKAIVESLKKSYLEDGLLKEDKEKYPIFVFIHKDKVTISIDTTGD
                     ALHKRGYREKANKAPIRETLAAGLIYLTPWKAGRVLVDPMCGSGTILIEAAMIGINMA
                     PGLNREFISEKWRTLDKKIWWDVRKDAFNKIDNESKFKIYGYDIDEESIDIARENAEI
                     AGVDEYIEFNVGDATQFKSEDEFGFIITNPPYGERLEDKDSVKQLYKELGYAFRKLKN
                     WSYYLITSYEDFEYEFGQKADKKRKLYNGMLKTNFFQYPGPKPPRNNK"
     gene            2239..3627
                     /locus_tag="JAM15_10815"
     CDS             2239..3627
                     /locus_tag="JAM15_10815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HAT6798745.1"
                     /translation="MKVLKLITVVALMMLFVTGCNIKTESPEQLAKIPDYDDTKKVLY
                     DGIDQLLKPDSSMILPSNTKEVGKINKVDLNSDGIDELVVFEQKEDLSNNVSQVGFVT
                     LSYNGEKYVLGDHFLENGESIEYANFYDLDSDGYKEVILLVKSKDKTNMHIYKVVDNE
                     ITKIYDLDASWLQNKEDFNDMKVKIGYIDGDDKLDILMLHLNNKTNEMFASVANFDGK
                     MKIKDSVKFENVKNLSELYITLGNVASSVGNSSAAIKGIVLDIPILKDNNYITQILYM
                     KDGKINKAFSDYDKTITKSYYIPVDDIDKDKIIEIPIVAGSTGNNKNTYSSKSSATIS
                     WYRWNGKEGADSSLIFTSQIYYNYKYNFKLFIPNNLFDKILVEQEFVGEKAVFKFYYF
                     DYSDRKNLFNIVVESKNKLEDRKNTGTQNSIVLQESDEYTFLLVVNNANEMDKLDMTI
                     DALKEYFSLIYG"
     gene            3656..4354
                     /locus_tag="JAM15_10820"
     CDS             3656..4354
                     /locus_tag="JAM15_10820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6798746.1"
                     /translation="MKEKILILEDEIGIRSFVSINLKREGYEIVEAGTGREAIEKMTT
                     ENDITIALLDVMLPDISGIEVCKFIRENFDQVGIIMLTAKAQEDDKIEGFISGADDYI
                     IKPFSIKELLVRVSALLRRVAKDDSSVKSSEIVSPPFILDIDKRKLFKNGKEIELTPT
                     EFSIVKYLISNAKQSLSRDQILDEVWGTNYLYDFKIVDVNIRRIRNKIEDDPSKPKYI
                     QTIWGYGYCFRKEE"
     gene            4357..5790
                     /locus_tag="JAM15_10825"
     CDS             4357..5790
                     /locus_tag="JAM15_10825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAT6798747.1"
                     /translation="MLHFEGLRKKVIKNYFIIIIIMVTLFEGLFMFYIQNYYYASVKQ
                     LLESEIKYADEYNAITMETTSFEKKVKNIFDKQPLTKNSEFGISIIDKDKNIILDQYG
                     FKSKEKANYEDVNNALKDIKTKNLTPYTYRIPDTGEHVMSISLPLKVNNIIEGVVRYT
                     VSLDAIDNAILKQATWLILAGIFILIIAILISLKFAETLIKPLRELKKFANELAVGNY
                     NIKLEKMKIVDDEIGDLAQTFEHMAHEIDKSEKLKEEFISSVSHELRTPLTSIKGWSE
                     TLGYESITREELDLGLGIIQDETERLIKLVEELLDFSRLSSDRIKLHVDIVDVEGLIV
                     GVVNQLKVKAAEKDISLLFEFENEFIENIQGDKNRLRQVLINLIQNSFKFTSQGGYIK
                     VVASQDEEITTISVEDNGSGIEKQNLNKVLDKFFQEDYNKAGSGLGLAISNEIVKLHG
                     GRMKIESEKNVGTKITFNIKNKFAKQA"
     gene            5812..6549
                     /gene="truA"
                     /locus_tag="JAM15_10830"
     CDS             5812..6549
                     /gene="truA"
                     /locus_tag="JAM15_10830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HAT6798748.1"
                     /translation="MRNIKMIVAYDGSRYKGYQKLGDNNMTIQEKLENVLSKMTNETV
                     EIIGSGRTDMGAHARGQVVNFRTNCMDSLDKIQKYLYEYLPEDIVVKTVEEVDERFHS
                     RYNVKSKTYMYKIDNNKYHNPFIRKYATHVSKKLDLDRMRKASEYLVGEHDFTSFASS
                     KSKKKSNVREIYSINIKEDDNVIEIYVEGNGFLYNMVRIIVGALIDVGLKRRAPQDIK
                     YMLESKDRCQSSDTAPAKGLCLWKVTY"
     misc_binding    6660..6867
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            7120..8319
                     /locus_tag="JAM15_10835"
     CDS             7120..8319
                     /locus_tag="JAM15_10835"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HAT6798749.1"
                     /translation="MKEKVVLAYSGGLDTSIIIPWLKENYEDIDVIAVCGNVGQEDKM
                     EDVYEKALQSGASKAYVDDISEEFVTETIFKAVKAEAKYEGKYLLGTSLARPIIAKKL
                     VEVAHKEGAKYICHGCTGKGNDQVRFEATIAALDPTIKVIAPWRIWDIKSREDAIDYA
                     EKHNIKVTATKAKIYSVDANLWHVSTEGGDIEHLENEHKKDVYKQCVDPEDACDVAEY
                     VEVYFEKGVPKKVNGEELSPVALIHKLNELGCKHGIGVIDIVENRLVGMKSRGIYETP
                     GGTILYEAHNILESATLDKDTLHFKQMVSYKYGELIYNGLWYCKLRESIDAFMEQTQD
                     NVTGTVKVKLYKGNIKPAGIFTENALYDEGISSFGNSELYDHKDAEGFINLFTLPLKI
                     RAMKAGK"
     gene            8567..9613
                     /locus_tag="JAM15_10840"
     CDS             8567..9613
                     /locus_tag="JAM15_10840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BtrH N-terminal domain-containing protein"
                     /protein_id="HAT6798750.1"
                     /translation="MRKIIEIKHHSHDYECMWNGIEDLYINKTGECLPNDFFFLLSGF
                     GSFCYMKTNKADLKRMVALGDGRTKQMYKFLAPIVGFEYKHHEFKKYEQALKKAKSEI
                     DGGYPVILGALDMYYLPYYKKLYHKEHIPFHYILMVGYDDERIYLYDCGRTELLHLSY
                     DKLRESMNCNSPGLSKENTICTIRMNTSKNKYNIAREAIAIKRDMFLNPPKGFLGYKG
                     FEKFIKELPQWNTELDKDDYDKILTNMVMFFGTVPTIPNAIKGIKEPDTVQFKGGFDK
                     MSRMINSIGEEYKNDSFIQVADIFDKTAIIIEKISNIIIDYLTQTCDDTEQLPLLFSE
                     VLEHMKTGYLILDV"
     gene            9721..10884
                     /locus_tag="JAM15_10845"
     CDS             9721..10884
                     /locus_tag="JAM15_10845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAT6798751.1"
                     /translation="MRTVKQVSDLTGISVRALHYYDEIGLLKPNKITDAGYRLYDDES
                     IKTLQQILFFKEIDIPLREVKEIMSSQYFDKVEALKNQKKLLILKRKRLDELIELINQ
                     TLRGEGNIDFKEFDMSEYFNVLEEFKREHRNKVIKIYGSVEKYNEYIERVKSNEEKIA
                     KMAIKQYGTIEKFAQAIKTNFSSDILNLGEKFDRYKNDCLKEKHPKLKELYRKLVEDL
                     SKNPSSTDLQEIAKEITDISKKDYEIFSMDTGDDNWYYMIQNYLVNPMWIEEVDKKYG
                     SGAGKFIGQVLKTYLRDRKPKINTLYEKLVEDLSRDCSSREVQSIVEEIDNEMKRSNE
                     FYKIDNGERYFDYMSELYLQDSNYIKVTDKNYGDGASKFIGEAFKIYFDNNNC"
     gene            complement(10973..11353)
                     /locus_tag="JAM15_10850"
     CDS             complement(10973..11353)
                     /locus_tag="JAM15_10850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4363 family protein"
                     /protein_id="HAT6798752.1"
                     /translation="MKSTTFVILWTILFVLFGFYVNNKLYDFTEGYKDNISVLEKSIE
                     NEDWEKAQKEADSISTSWNKEKNHWYKVLNHEYFDEIGLRFNILDKAIYTENKLKSLE
                     EVESIKTYLGNIIESVKFDVNYIF"
     gene            complement(11356..12015)
                     /locus_tag="JAM15_10855"
     CDS             complement(11356..12015)
                     /locus_tag="JAM15_10855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HAT6798753.1"
                     /translation="MTVVLIRSIILYITVLIALRVMGKGEIAEMNCFDLVITLLIAEV
                     ASVPMENNNIPIINGVAAISGLVIMQTLISFLSLKSRKLSSFLSGKPSVLIDKGKIVY
                     KELKKERISIDELLEQLRIQGYFNLKDVQYAILETDGNLSVVPASSYNSTPPRAFNHL
                     PIPLILDGRIINKNLDIAQKDTNWLMGILKSNHIETFKDVLICVLDENDKIFIQNKKG
                     D"
     gene            complement(12121..13095)
                     /locus_tag="JAM15_10860"
     CDS             complement(12121..13095)
                     /locus_tag="JAM15_10860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HAT6798754.1"
                     /translation="MKYKLFIDFEFNILDDNKNKPKEYNGAELISIGGVLVDNEFNTI
                     DNYYSLVKPKYNKILSNKCKNLTKLNQLDINNAPNLLYVMDDFYKWFCKFDDVTIYNW
                     GDFDITGLLTSFRVYKYTGKCLELFNMMIDIQPFISQHITYNNRILSKQISLLNMKKI
                     FSVEGDIKHNSLSDAVDLMNVCKCFFFNSPKNIDILEELYNKLPALKTPLYYIPYFED
                     ENFELKFDRTPEDIIIYLKQILTILNISKKEIYFKKRSVLVNNSKIINFKNLSSSFKL
                     IKLNEFEEYPDFILKLGDKKSFVESVIKINKSNRKSIKNLILKLSKKP"
     gene            complement(13135..13482)
                     /locus_tag="JAM15_10865"
     CDS             complement(13135..13482)
                     /locus_tag="JAM15_10865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798755.1"
                     /translation="MLNLKEIREEIIKKYIGDSLISELTEELKNILITDLQSNPFKSN
                     IELSIIPANIEIFKKIENILIDSKVNLKMGWERILINYILKDLFELNYEINKSCNEPL
                     MFRVIISIDSYDA"
     gene            complement(13700..14656)
                     /locus_tag="JAM15_10870"
     CDS             complement(13700..14656)
                     /locus_tag="JAM15_10870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HAT6798756.1"
                     /translation="MKKILITGALGQIGSELTIKLRNEYGEQNVIASSRRVKEGNPVC
                     ESGIFEILDVTDKNRFFEIAKKYDVDTIIHLASLLSAVAESKPLEAWNLNMNGLINGL
                     EIAKELDCKFFTPSSIAAFGENSPKNMTPQDTLQRPNTMYGVTKVSGELLCDYYHSKF
                     GVDTRGVRFPGLISYVTPPGGGTTDYAVDIYYEALKNKRYKSYIAEGTKMDMMYMPDA
                     LQSIVDLIQAPADKLIHRNAFNITAMSFSPEEIADSIKKYIPDFVIEYDVDPVRQSIA
                     DSWPNSLDSSSAVKEWNFKFSYDLDKMTKDMLEKLSEKGIGK"
     gene            15099..15467
                     /locus_tag="JAM15_10875"
     CDS             15099..15467
                     /locus_tag="JAM15_10875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HAT6798757.1"
                     /translation="MTRPSIYHSQGYTCAEALIKSYNEEHNTDIPISIGSGMGVGMNV
                     GSVCGAVNAAVVIIGYLNGRNSNLDENIARKYSRELLNKVRNKYSSEICVSLKKNKVT
                     CEEIINFTYDALNDMLKNQK"
     gene            15892..16137
                     /locus_tag="JAM15_10880"
     CDS             15892..16137
                     /locus_tag="JAM15_10880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798758.1"
                     /translation="MFIDEELEGYILTCKISEDFKNIPEYSDEEFYVTVYKDESSDSG
                     YYALLENKEERVVWDGEVVANNIFNNLWIVVNKVKTG"
     gene            16236..16499
                     /locus_tag="JAM15_10885"
     CDS             16236..16499
                     /locus_tag="JAM15_10885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1883 domain-containing protein"
                     /protein_id="HAT6798759.1"
                     /translation="MEYSYSKMNLKKGDIVEVNLEKQANVILLDHINYVKFKNQRNYD
                     YYGGFAKKNPCRMRVPNTGTWYLVVNQDGNSGIVNFSINTIQN"
     gene            complement(16784..17731)
                     /locus_tag="JAM15_10890"
     CDS             complement(16784..17731)
                     /locus_tag="JAM15_10890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
                     /protein_id="HAT6798760.1"
                     /translation="MSNVTAEQKKEVKGRGFLPSRDGEHFAARIITVNGVINASQAKK
                     IAEAAEKFGNGQLAFTTRLTVELPGVKFEDIEALSEFIASENLITGGTGSRVRPVVAC
                     KGTVCVHGLADTQALAAEIHEEFYKNWYDVKLPHKFKIGVGGCPNNCIKPDLNDLGIV
                     GQRVPDYDSELCVGCKKCAVVEVCPVKAAKLTDKGKLEIDSNLCNNCGKCIESCNFDS
                     IEEKESGYKVYIGGKWGKSVRPGTQIDRLFSKEELMTLIEKAILLFREQGNTGERFGI
                     TIDRIGADKFIEMLLSDEVLERKEEILEALLHLTGGAVC"
     gene            complement(17734..19365)
                     /locus_tag="JAM15_10895"
     CDS             complement(17734..19365)
                     /locus_tag="JAM15_10895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAT6798761.1"
                     /translation="MKVLIIGGVAAGTKTAAKIKREMGDNCSVTILNKGDDISYAGCG
                     LPYYVGKIIEDKSSLIVNTPESFSKLTGAEVRCGVEVTSIDRNAKQVTLKTLSTGEKE
                     NLSYDKLVIATGADPIKPPIPGIDLPGVFFMRTPNDAIKLRDSIENGIKRAVVIGGGF
                     IGLEIAENLSAMGIRVSVVDMAEHVMPGFDTDFAEYVENHMADKGIMIFTGDQVVGIE
                     GENKVEKLRTKNRAIKTDLVVMSVGIRPNTGFLKDTGLEFAPNNTIIADEYMLTNDKD
                     IYVVGDCAFVKNSLTNKPTWSPMGSSANHEGRICAQNISGKSKTYNGVLGTTVVKLPE
                     LNAGKTGLSKEIAEKEGYNVCSVTIATDDKAHYYPGASNFIIRMVAEKNTRKLLGVQV
                     MGPGAVDKIVDIAATAITLGADLYSLESMDLAYAPPFSTAIHPFVVAVNVLQNKLNGE
                     LDSVLLDEIEDFDSWTKLDVSKAPSIPSLRYIPVGEINGEIEGLAKDEKILLICAKGK
                     NSYMAQNRLRRFGYTNTKVLEGGILFYPNLKVMEE"
     gene            19495..20412
                     /locus_tag="JAM15_10900"
     CDS             19495..20412
                     /locus_tag="JAM15_10900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAT6798762.1"
                     /translation="MTIRSLEIFVKVAECGKMSEVARNMYITQSSVSQAISEIEKEYG
                     VKLFDRISKKLYLTEAGKKLLGYGRHLLAVNEEMNDCMKHCAKNIRIRVGATVTVGTC
                     VISPIMLELYKVNPLIEPEVFVEDTRLIAKKLLNSELDIAIVEGKIKHPDIVTKSIIN
                     DNLVLICSHKHEFYKRDSIKVSELSNQPLIMRELGSGTRAQLEKQLKELKIPMNIRWS
                     CYNSEAILRAVVDNFGIAVISELLIEDYLKKHLLWACDIEGINLHRTFDIAYHRSKFF
                     TENISAFFDISVEYGKKQARKKSRSVNSL"
     gene            complement(20469..21050)
                     /locus_tag="JAM15_10905"
     CDS             complement(20469..21050)
                     /locus_tag="JAM15_10905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HAT6798763.1"
                     /translation="MGITLAKGQKVSLTKSNPGLKKVIVGLGWDINKYDGGFDFDLDA
                     SAFLTGTDGKVTNDGDFIFYNNLKHASEAVEYMGDNRTGVGDGDDEQINVDLSKIPQN
                     IAKISFSVTINEAITRRQNFGQVENSYIRIYNEETNEELIKYELGEDFSIETAIVVAE
                     LYRHNGEWKFNALGSGFEDGLAGLCKNFGVNIG"
     gene            complement(21090..21656)
                     /locus_tag="JAM15_10910"
     CDS             complement(21090..21656)
                     /locus_tag="JAM15_10910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HAT6798764.1"
                     /translation="MSVSLQKGQRVSLVKDNNPVKNLVVGLGWDMNKLGKKNYDLDAF
                     AIALTNQDKMNVRGDLVYFGNLKHPSKAIIHTGDNLTGKGEGDDEQIIVNLEDIPEYV
                     HKIVFGVSIYKAKKRDQDFGQMNNSFIRLIDSNSKQELFKYNLQEDFSGKVTVLAGEI
                     YRRNEEWKFNALGIGQNEELRELINTYK"
     gene            complement(22092..22952)
                     /locus_tag="JAM15_10915"
     CDS             complement(22092..22952)
                     /locus_tag="JAM15_10915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAT6798765.1"
                     /translation="MLLKKDRITFSEILILIVGCILMAISLNLFFNPHAIAAGGITGL
                     GVVLNSLFGVELWIVNLLLNVPLFIFAYKILSKKDCFKTVLGIIFLTIALKLTANMAT
                     LDITNDMYLAIISGSILMGVGQGLIFRINGSTGGTDLMALLLNKYFPTFSIPVLMGIV
                     DCVVVVLSGIVNRQVEIALYSTVALYILVKVSDLLIEGFNYSKSFTIISDLSKDISKK
                     IMEDLDRGATILKGEGAYTGENKNVLLVVVEKKEVVELKKLVKNVDPNAFIIITDIHE
                     ALGNGFKKIE"
     gene            23101..23991
                     /locus_tag="JAM15_10920"
     CDS             23101..23991
                     /locus_tag="JAM15_10920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAT6798766.1"
                     /translation="MAKLTLEHIKGNTYYIPLPTIVGVYVDGKDAILIDSGNNKDTAR
                     QVLRLLEEHNLSPKLIINTHSNADHIGGNAYLKNQTKCKIATTKIEGYFTENPILESA
                     FLYGGYPSKALKNKFLLAKESEVDYIIPSNGKIVDTELEAISLPGHYFEMIGVRTPDN
                     VLFVADSLTPENIITKYHFFFLLDIDSQFKTLEKLRMLEADFFVPSHSVKTTDIKSLI
                     NINKKKMEEIIDNIKKVCYEPVMIDEVIEKMCDLYNVKLDANQYVLVGSTIRSYITYL
                     YENNMVEYIFDGGKMMIKAV"
     gene            24209..25963
                     /locus_tag="JAM15_10925"
     CDS             24209..25963
                     /locus_tag="JAM15_10925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp23"
                     /protein_id="HAT6798767.1"
                     /translation="MYIMNKKFKKFSKKLSILILVLTMFLFNNLTANAQIKEDSIIGI
                     DRYETAGLIADRQTYDTVILVNGDKNLSDGLSSSGLAGAINAPILLTKKSEIPKATLN
                     RLDNKSLNVVKKVYIIGGYNTIENSVEKDIKRKGIQVERINGNNRIETSYNVAKKINE
                     VSSVKEVMLTNGFVGEADAMSIAPVVAKNKGAIILTDGKSVPFKTEGLNVYAIGGKSA
                     IKEDLVNETKATRIGGNDRFETNKKVMEKFYNGATDFYITNGYQLVDALTLSPLAKEK
                     PIVLVADGSNKGILKGAKSITKVGGIDANIYKQCLDMIKYNNMDVTPNILKHLTSVEG
                     NEVSEILIESDNLGVVVEKTNTNKFEFDYVSVTNEKNCTFSVYKENSSNNVKNGKLVV
                     SAKKKIDKKDSDLQDMNGDNMINANKDRMVNVIKIGVPDKMYSNFKIDVESGSVELYN
                     IKGGATVDVNDGIANIVDNNVTNPFNINTNSGISGVTAETISSEIKFRANNGIVSVTA
                     TNINGNISLFGSDNKGTFDGIFKLNLKKEPSNLHLKLVGNGINKLPEGWSKDYILGNG
                     QPIIEVKNNGINNISIGE"
     gene            26347..27333
                     /locus_tag="JAM15_10930"
     CDS             26347..27333
                     /locus_tag="JAM15_10930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAT6798768.1"
                     /translation="MKKITINDIANLAGVSKSTVSRYLNNKDISDSTKEKIKTIIDEY
                     GYEPNAFAQSLRAKKTYFIGIITPCLDSFVKSKIMMAIDEELKELKYTSLIINTNRKI
                     RSEIDSISKLASLKVDGIILIGTEITKEHKNEIEKLDIPMVVVGQKVDGINSIVNDDY
                     GAGYKMGQYIANKGYKNIVYLGVDESDISVGLNRKNGVLNGLKDKGYDAKVFYTDFDQ
                     ETSIQRSGEMLESENPDIIICATDNIAIATMKEINKRGKNIPQDISVAGFGGYDVLSI
                     ISPKLTTIKFENKNAGKVAANTIVNLIQERKEPLLKEIKFELIEGESTINKN"
     gene            27501..27647
                     /locus_tag="JAM15_10935"
                     /pseudo
     CDS             27501..27647
                     /locus_tag="JAM15_10935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423822.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIB"
     gene            27669..29150
                     /locus_tag="JAM15_10940"
     CDS             27669..29150
                     /locus_tag="JAM15_10940"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HAT6798769.1"
                     /translation="MYKEPKYRTILESTKEELNKLRNISLNDKYKPLFHIHPQHGLLN
                     DPNGLAYYNGKYHVFYQWYPYDATHGMKHWAYVSSDDFVNWNREDVALIPIESYESHG
                     AYSGNAIEVDGKLHMYYTGNIKYSAEDRYAYQNLAIMNKDGKITKYENNPIVSEIPKG
                     YTGHVRDPKVFKRKDKYFMLLGAQTSDKKGVIIVYESKNSIDWNFKGELNVKNIDEDF
                     GYMWECPDYINIDEKDILIFSPQGVEPKGFDYQNIYNVVYAIGNMDLDNLTFEIDTMK
                     ELEKGFDFYAPQTFIKDSQIILFAWAGMGEVLYPTDKNKWAHCLTVPRKLNIKNNKLL
                     QMPVDELIKLRYDETSGQNTIKNNINIIENDENVYELNINIKNIDSNKFGLELFSSQD
                     EGVKLEFNKLGNIVTLDRSNFKKVFGVEYGTNRKEYINIDENINIKVLADRSVLEIFI
                     NDGEVVFTSRIFAKENSNQIRVYSDKIVEYEYTKFKLKQGIEL"
     gene            29176..30147
                     /locus_tag="JAM15_10945"
     CDS             29176..30147
                     /locus_tag="JAM15_10945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="HAT6798770.1"
                     /translation="MKKVISIGEALIDFIPNQNGCKLKNVSEFRRVAGGAPANVSVVV
                     AKLGGKSSFISKLGKDAFGDYIIDVLNEVNVNTDYVLRTSKANTGLAFVSLKEDGNRD
                     FSFYRNPSADMLLEADEVKKEWFNNCHILHFCSVDLIDSPMKLAHKKAIEYALESNSI
                     ISFDPNIRLPLWDSEQSCKKAISEFLPFAHIVKISDEELEFMTGENDIEKSLHKLFVG
                     NVELVLYTKGKDGVDAYTKKVKGMCKGVKVNAIDTTRAGDSYIGSFLYTLLYKQITLN
                     DIKEMKQETLNEYLEFSNYYAARSTTIKGAISSYATKEEITEFIKNL"
BASE COUNT        11857 a         3481 c         4753 g        10163 t
ORIGIN      
        1 taaaataaat actttatatg ttataatcat taagaatgta aaaaaataat atatagtttt
       61 atagttcata tttttccaga tatggaggta aattttgtga aggaaaaaga aaaattagat
      121 aaattaaaaa aaatgttact tgaattaggc agtgttgtag ttgcttattc tggtggagta
      181 gatagtaatt ttttgcttaa ggtcgcaaaa gatacattag gtgaaaatgt tatagctgtg
      241 accattcatg caatgatgca ttcaagtagg gaaattgaag aggctaaaca atatactcaa
      301 aattttggcg ttaaacatat catattaaat atagaaaact ttgatttaaa agaatttaaa
      361 gaaaatggtg ttgatagatg ttatcattgt aaaaaatata tattctctaa aataaaagag
      421 gtagcaaaag aacataatat aaagtacata gtagatggaa caaatataga tgatttagga
      481 gactatagac ctgggcttaa ggcattgagt gaattaggag taattagtcc attaaaagat
      541 agtagtttaa aaaaagaaga aattaggtcg ctttcaaaaa cattaggatt aaatactttt
      601 aataaaccat catttgcatg tcttgcgagt aggatacctt atggagttga aataacagat
      661 gaaaatttaa gaatagtaga aaagagtgaa gaatatctat ccaatttagg tttttctcaa
      721 tttagagtga gaatgcatgg agatatagct agaatagaag ttggacagga agaactaggt
      781 aaattttttg aaaataacaa ttttaataaa gttgatacta aattaaaaat atttggcttt
      841 aaatatgtta cactagatat gtcaggatat aaaatgggaa gtatgaattt aaatgtgtag
      901 attattttaa aaataaataa gttttatagt taatataagg aaacaggagg ttttatgaaa
      961 aattatacgt taatatcgcc atgttttttt ggaatggaaa aaatgctggc tagagagatt
     1021 actaatttag gatatgaaat aataaaaaca gaagatggaa gaataacata taaaactgat
     1081 gagtttggaa tagcaaagtc aaacatgtgg ttgagatgtg ctgaaagagt acatcttaaa
     1141 attgctgaat ttgaggcaaa aagctttgat gaattatttg aaaatacaaa aagaataaac
     1201 tggtctagat atatacctta tggagctcaa tttcctatat caaaagcttc ctctataaaa
     1261 tcaaaattat acagtacacc agatgtacaa gccatagtaa aaaaggctat agtagaaagc
     1321 ttaaagaaaa gttatttgga ggatggtttg cttaaagaag ataaggagaa ataccctatt
     1381 tttgtattta tacacaaaga taaagtaacc atttctatag atacaacagg agatgctttg
     1441 cataagagag gatatagaga aaaggcaaat aaagctccaa taagagagac tttagctgct
     1501 gggcttattt atttaactcc ctggaaagca ggtagagttt tagtagaccc tatgtgtggt
     1561 tctggtacta tattgattga agctgctatg attggtataa atatggcacc tggcttaaat
     1621 agagagttta tatcagaaaa gtggagaact cttgataaga aaatatggtg ggatgtaaga
     1681 aaagatgctt ttaataagat agataatgaa tctaaattta agatttatgg atatgatata
     1741 gatgaagaat ctatagatat agctagagaa aatgctgaaa tagcaggtgt agatgaatat
     1801 atagagttta atgtaggaga tgcaactcaa tttaaaagtg aagatgagtt tggatttata
     1861 atcactaatc ctccttacgg agaaagatta gaagataaag acagtgttaa acagttgtat
     1921 aaggagcttg gttatgcatt tagaaaatta aaaaattggt cgtattattt gataacttct
     1981 tatgaagact ttgaatatga gtttgggcaa aaagcagaca aaaaaagaaa attgtataat
     2041 ggtatgttaa aaactaactt tttccaatat ccgggtccta agcctcctag aaataataaa
     2101 taagttttac atgatttatt tgtaaaatat aaaattttat taaaataagt aaaacattat
     2161 gatgccttga aacgtctaat tattgtgagg agatttttgt gaacaaattt aaagatttat
     2221 aggattagga ggagttaaat gaaagtgtta aagcttatta ctgtagtagc cctgatgatg
     2281 ttatttgtta ctggatgtaa tataaaaact gaatctccag aacaattagc gaagatacct
     2341 gactatgatg atacaaaaaa agtattgtat gatggtattg accagttact aaaaccagat
     2401 tcatctatga tattgccttc taatacaaaa gaagtaggaa aaataaataa ggtagattta
     2461 aacagcgatg gaattgatga attagtagta tttgaacaaa aagaagattt aagtaataat
     2521 gtgagtcagg tagggtttgt aaccttgagt tacaatggag aaaaatacgt acttggagac
     2581 cattttttag aaaatggcga atcaatagaa tatgctaatt tttatgattt ggactcagat
     2641 ggatataagg aagttatctt attggttaaa tccaaagaca aaacgaatat gcatatatat
     2701 aaagtagtag ataatgaaat aacaaaaata tatgacttgg atgcatcatg gcttcaaaat
     2761 aaagaagatt ttaatgacat gaaagtaaaa attggatata tagatggaga tgacaagtta
     2821 gacatattga tgcttcattt gaataataag actaatgaaa tgtttgcaag tgttgcaaat
     2881 tttgatggga aaatgaaaat caaagattct gttaagtttg aaaatgtaaa aaacttaagt
     2941 gaattatata taacattagg taatgttgct tcatctgttg gaaattcttc tgcagctata
     3001 aaaggtattg tacttgatat tcctatattg aaagataata actatattac gcagatactt
     3061 tatatgaaag atgggaaaat taacaaagct tttagtgatt atgataaaac tattactaaa
     3121 tcttattata tacctgtaga tgatattgac aaagataaga ttatagaaat acctatagtt
     3181 gcaggcagta caggtaataa taaaaatact tatagttcta aatcatctgc aactataagt
     3241 tggtatagat ggaatggaaa agaaggtgct gattcaagtt taatatttac aagtcagata
     3301 tattataatt ataaatataa ttttaaatta tttattccaa ataatttatt tgataaaata
     3361 cttgttgaac aggaatttgt tggagaaaaa gcagtattta aattttacta ttttgactat
     3421 tcagatcgta agaatttatt taatatagta gtagagagta aaaacaaact tgaagataga
     3481 aaaaatacag gtactcaaaa ctctattgta cttcaagaga gcgatgaata tactttctta
     3541 ctagttgtaa acaatgcaaa tgaaatggat aagctagata tgactataga cgcattaaaa
     3601 gaatatttct cattaatata tggttaatat tatactcaat tggaggtttt attttatgaa
     3661 ggaaaagata cttatactag aagatgaaat tggtattaga agttttgtta gtataaactt
     3721 aaaaagagaa ggctatgaaa tagttgaggc aggtactgga agagaagcta tagaaaaaat
     3781 gacaacagaa aatgatatta caatagctct tttagatgtg atgcttccag atataagtgg
     3841 tatagaagta tgtaaattta taagggagaa ttttgaccaa gtaggtataa taatgcttac
     3901 tgctaaagct caagaggacg ataaaataga aggatttatt tcaggagcag atgattacat
     3961 cataaaacca tttagtataa aagagctttt agtcagggtt tctgctcttc ttagaagagt
     4021 agcaaaggat gattcaagtg ttaagtcgag tgaaatagtt tctccaccat ttatacttga
     4081 tatagacaag agaaaattat ttaaaaatgg aaaggaaatt gagcttacac caactgaatt
     4141 ttcaatagtg aaatatctaa tatcaaatgc taagcaatcg ttaagtagag accagatatt
     4201 agacgaagta tggggaacta actatttata tgattttaaa atagtagatg taaatataag
     4261 aaggataaga aataaaatag aagatgaccc atcaaagcca aaatatatac aaactatttg
     4321 gggttatgga tactgtttta gaaaggaaga ataatagtgt tacattttga aggtctgaga
     4381 aaaaaagtaa taaaaaacta ttttataata attattataa tggttactct gtttgaagga
     4441 ttgttcatgt tttacataca aaattactat tatgcttctg tcaaacaact acttgaatct
     4501 gaaataaaat atgctgatga atataatgct attacaatgg aaactacaag ttttgagaaa
     4561 aaagtaaaaa atatatttga taaacaacca ttaactaaaa attcagaatt tggaatttca
     4621 ataatagata aagataaaaa tattatatta gaccaatatg gttttaaaag taaagaaaaa
     4681 gcaaactatg aagatgttaa caatgcatta aaagatataa aaactaaaaa tttaacacct
     4741 tatacttata gaataccaga tacaggggag catgttatga gtatctcctt accacttaag
     4801 gtaaataata taatagaagg tgttgttaga tatacagtat cattagatgc tattgataat
     4861 gcaatattaa agcaagctac atggcttata ttagcaggaa tatttatact tattatagct
     4921 atactaataa gtcttaaatt tgctgagact cttataaaac cattacgaga gctaaagaaa
     4981 tttgcaaatg aattggctgt aggaaattat aatataaaat tagaaaagat gaagattgta
     5041 gatgatgaga ttggtgattt agcacagaca tttgaacaca tggcacatga gattgacaaa
     5101 agtgaaaaat taaaagagga atttatatca tctgtatctc atgaactaag gactcctctt
     5161 acatctataa aggggtggag tgaaacctta ggttatgaaa gtataacaag agaagaacta
     5221 gacttaggtt taggcattat acaagatgaa acagaaagac ttataaaact agttgaagaa
     5281 ttattagact tttcaaggct ttcttcagac aggataaaac ttcatgttga tatagttgat
     5341 gttgaaggtt taattgtagg tgttgtaaat caacttaaag ttaaagcagc tgaaaaagat
     5401 atatcacttt tatttgaatt tgaaaatgaa tttatagaga acattcaagg agataaaaat
     5461 agattaagac aggttctcat aaatttaata caaaattcat ttaaatttac gagtcaaggt
     5521 ggttacataa aagttgtagc ttctcaagat gaagagataa caaccatatc agtagaggat
     5581 aatggttcag gtatagaaaa gcaaaattta aataaagtgt tagataaatt tttccaagaa
     5641 gattataata aggctggtag tggattagga ttagcaatta gtaatgaaat tgtaaaactt
     5701 catggtggaa gaatgaaaat agaaagtgaa aagaatgttg gaacaaaaat aacttttaat
     5761 ataaaaaata aatttgctaa acaagcataa attcttagaa agaggattaa gatgagaaac
     5821 ataaaaatga tagtagcata cgatggttca agatataaag gatatcaaaa attaggtgac
     5881 aataatatga ctattcaaga aaaacttgaa aatgttttaa gtaaaatgac taatgaaaca
     5941 gtggagataa tagggtctgg aagaactgat atgggagctc atgcaagagg acaagtggta
     6001 aattttagaa ctaattgtat ggattctttg gataaaattc aaaaatattt atatgaatat
     6061 ttaccagaag atatagttgt aaaaactgtt gaagaagttg atgaaagatt tcattcaaga
     6121 tacaatgtaa aatcaaagac ttatatgtat aaaattgaca ataataagta tcacaatcct
     6181 tttataagaa aatatgctac tcatgtaagt aaaaaattag atttagatag aatgagaaaa
     6241 gcaagtgagt atttagtagg agaacatgat tttactagtt ttgcttcttc taaatctaag
     6301 aaaaaatcaa atgtaagaga aatttattct ataaatataa aagaagatga taatgttata
     6361 gaaatatatg tagaaggaaa tggatttttg tacaacatgg taaggataat agtaggtgct
     6421 ttgatagatg ttggtctaaa aagaagagct ccacaagata ttaagtatat gcttgaatca
     6481 aaagatagat gtcaatcatc agatactgca ccagctaaag gactatgtct ttggaaagta
     6541 acatattagt caattatata aaactctctt taaaataaaa ataaaataaa ttatatagtt
     6601 gacataaatg gaaaaataaa ctattatata ttttataaga gagatataaa actttatatt
     6661 taaatcctgt gagaaagaga gtaacttcta tgtgttttat agagagctga ggatggtgga
     6721 agcttagcaa ataagtatta gtgaaaagaa ctttggagga tactaattga atttagtatg
     6781 ttagtaggta atctcgcctt aagagaaaga gtggataagt ttatcttatc aattagagtg
     6841 gtaacgcgga tatatttcgt ctcttggttt ttccaagagg cgttttttaa tatatttaat
     6901 tattagtgtt tatctggtat gttgaacatt tactaattga ttagctaagt ttatcaataa
     6961 gagtggtacc gcggatattt cgcctcttag tattttaaaa tactaagggg tttttttagt
     7021 attaaaatga ttttatgtga gtctaaattc tcagagtcat tcaatattaa gaatttctat
     7081 aaaataaaaa ttataattta agattgggag gaattaaaaa tgaaggaaaa agtagtatta
     7141 gcatattcag gaggacttga cacatcaatc ataatacctt ggttaaagga aaattatgaa
     7201 gatatagatg ttatagctgt ttgtggaaat gtaggtcagg aagataaaat ggaagatgta
     7261 tatgaaaaag ctttacaaag tggagcatca aaggcatatg tggatgatat aagtgaagaa
     7321 tttgtaactg aaactatatt taaagccgta aaagcagagg ctaaatatga aggaaaatac
     7381 ttattaggaa cttctttagc aagacctata atagctaaaa aattagttga agttgctcat
     7441 aaagaaggtg caaaatatat atgccatgga tgtacaggaa aaggtaatga ccaagttaga
     7501 tttgaagcta caattgcagc tcttgacccg actataaaag ttattgcacc ttggagaatt
     7561 tgggatataa aatcaagaga agatgctata gactatgctg aaaaacataa tataaaggta
     7621 acagcaacta aagctaaaat atattcagta gatgctaacc tttggcatgt ttcaacagaa
     7681 ggtggagata tagagcacct agaaaatgaa cataaaaaag atgtttataa acaatgtgta
     7741 gacccagaag atgcatgtga tgtagctgaa tatgtagaag tttactttga aaaaggtgta
     7801 cctaaaaagg taaatggcga agaattatct ccagttgcac tgattcataa gttaaatgag
     7861 ttgggttgta aacatggaat tggtgttata gatatagttg agaatagact tgttggtatg
     7921 aaatcaagag gtatatatga gactccagga ggaacaatcc tttatgaagc acataatatt
     7981 ttagaaagtg ctactttaga caaagataca ttacatttca aacaaatggt atcttataaa
     8041 tacggagaac ttatttacaa tggactatgg tattgtaaat taagagaatc tatagatgca
     8101 tttatggaac aaactcaaga taatgttaca ggaacagtaa aagttaaact ttacaaagga
     8161 aatataaaac ctgctggaat atttactgaa aatgctcttt atgatgaagg aatatcttct
     8221 tttggaaata gtgaacttta tgaccacaaa gatgcagaag gatttattaa tttattcact
     8281 ttaccattaa aaatcagagc tatgaaagct ggaaaataat aaaataaatt atttaagagt
     8341 gtataaaaac tatttttagg ttttttatat gctctttttt tatttgaatt tattaaatta
     8401 tacagtaaat agtataaaaa aatatattat agttccaaat gacttaataa tgtgaaaata
     8461 taagacctaa aatataaatt ttataaatac aatagttatt gactctctca ttgtaagagg
     8521 gtttatactg aatctaatga aaatttatag tgaggagata gattatatga gaaaaataat
     8581 tgaaattaaa catcattcac atgattatga gtgtatgtgg aatggtatag aagatttata
     8641 tataaataaa accggtgaat gccttccaaa cgattttttc tttttactgt caggttttgg
     8701 ttcattttgt tatatgaaaa caaataaagc tgatttgaaa agaatggtag ctttgggaga
     8761 tggaaggaca aaacagatgt ataaattttt agcaccaatt gttggatttg aatacaaaca
     8821 tcatgagttt aaaaagtatg agcaagcatt aaagaaagca aaatctgaaa ttgatggtgg
     8881 atatccagtt attttaggag ctttagatat gtattatcta ccatattata agaagctata
     8941 tcataaagaa cacattcctt ttcattatat attaatggta ggatatgatg atgaaagaat
     9001 atatctgtat gattgtggta gaacagaatt attacatctt tcttatgata aattacgtga
     9061 aagcatgaat tgcaattccc ctggattaag caaagaaaat actatttgca caataagaat
     9121 gaatacttca aagaataaat ataacattgc tagagaagct attgctataa agcgtgatat
     9181 gtttttaaat ccacctaaag gatttttggg atataaaggt tttgaaaagt ttattaaaga
     9241 gttgccacag tggaacactg aattggataa agatgattat gataagattt tgaccaatat
     9301 ggttatgttt tttggaacag taccaacaat tccaaatgca atcaaaggaa ttaaagaacc
     9361 agatactgtt caatttaaag gtggatttga taaaatgagt agaatgatca acagtattgg
     9421 ggaggaatac aaaaacgact cttttataca agtagctgat atttttgata aaactgctat
     9481 tataattgag aaaatatcca atattataat agattattta actcaaacat gtgatgatac
     9541 agaacaactt ccgttattgt tctctgaggt attagagcat atgaaaacag gatatttaat
     9601 cttggatgta taaaaaatat attgttgacc ctaacattac gtaatagtgt aatatgaaaa
     9661 tatagcttga atatattagt aggtattgat ggctgtaaaa ttaaaatttg aggtgtggat
     9721 atgagaacag tgaaacaagt ttctgattta actggaataa gtgtgagggc attacattat
     9781 tatgatgaaa taggtctttt aaaaccaaat aaaattacag atgcaggata tagactttat
     9841 gatgatgaat ctattaaaac tcttcaacaa attttatttt ttaaggagat tgatattcct
     9901 ttaagagagg ttaaggaaat aatgtcaagc caatattttg ataaggttga agctctaaaa
     9961 aatcaaaaaa aattacttat tttaaaacga aagagactgg atgaattgat agagcttata
    10021 aatcaaactc taagaggaga aggaaatatt gattttaaag agtttgatat gagcgagtat
    10081 tttaatgttt tagaagaatt taaaagagaa cataggaata aggtaattaa aatttatggt
    10141 agtgtagaaa aatacaatga atatatagaa agagttaagt ctaatgaaga gaaaattgct
    10201 aaaatggcta taaaacaata tggaactatt gagaagtttg cccaagctat aaaaacaaat
    10261 tttagcagtg atatattgaa tttaggagaa aaatttgata gatataaaaa tgattgttta
    10321 aaagaaaaac atccaaaatt aaaagaatta tatagaaagc ttgtagaaga tttaagtaag
    10381 aatccttctt caacagacct tcaagaaata gcaaaagaga taacagatat atctaaaaaa
    10441 gattatgaaa ttttctctat ggatactggt gatgacaact ggtattatat gattcaaaat
    10501 tatctagtaa atcctatgtg gatagaagaa gtagataaaa agtatggaag tggagcaggc
    10561 aagtttattg gacaagtact aaagacttat ctaagagata gaaaaccaaa gataaataca
    10621 ttgtatgaaa aacttgtaga agatttgagt agagattgtt cttcaaggga agttcaaagc
    10681 attgttgaag aaatagacaa tgaaatgaaa agaagtaatg aattttataa aatagacaat
    10741 ggtgaaagat actttgatta tatgtcagag ctttatttac aagattctaa ctatataaaa
    10801 gtaactgata agaattatgg tgatggtgca tctaagttta ttggagaagc ttttaagatt
    10861 tattttgata ataataattg ttgaaaattt ggaagtaaaa aatatgtaag ttttataaaa
    10921 gcacaaaaat aaggatgtag attagctcca tctatatcct tatttaaagt tattaaaata
    10981 tatagtttac atcaaactta acactttcaa taatatttcc caaatatgtt tttatacttt
    11041 caacttcttc taaagatttt aatttatttt cagtataaat tgctttgtcc agaatattaa
    11101 accttaatcc tatttcatca aagtactcat gatttaaaac tttgtaccaa tggttttttt
    11161 ctttattcca actcgtagat attgaatcag cttctttttg agctttttcc caatcttcat
    11221 tttctataga tttttctaaa acagatatat tgtctttata tccttctgta aaatcatata
    11281 gtttattgtt aacgtaaaat ccaaataata caaataagat agtccatagt ataacaaatg
    11341 ttgtagattt caatattaat cacccttttt attttgaata aatattttgt cattttcatc
    11401 taaaacacaa ataagaacat ctttaaaagt ttctatgtga ttagatttta aaatacccat
    11461 taaccagtta gtatcttttt gagctatgtc tagattttta tttattattc taccatccag
    11521 tataagtggg ataggtaaat gattaaaagc tcttggagga gtactattgt agcttgatgc
    11581 tggtacaaca cttagattac catcagtctc caaaatagca tattgtacat cttttaggtt
    11641 gaagtatcct tgaatcctaa gttgttctaa taattcatct atactaattc tttctttttt
    11701 aagctcttta tatacaattt ttcctttatc tattaataca gaaggtttac ctgataaaaa
    11761 tgaacttaat tttctgcttt ttaatgataa gaatgaaata agagtctgca tgattacaag
    11821 accagatatt gctgcaacac catttatgat tggtatatta ttattttcca ttgggacaga
    11881 tgcaacttct gcaattaata gtgttataac taaatcaaaa cagttcattt cagctatttc
    11941 accttttccc atgactctaa gtgcaattag cactgttatg tataatataa tacttcttat
    12001 taatactact gtcatatcta tcaattactc ctttaaaaaa tatttacact tagttagtat
    12061 atcctatata aaaaatttaa ttcaaagtat aaaaaacctt aaataattgg attcaactat
    12121 ttaaggtttt tttgataatt ttaatattaa attttttatg gattttctgt tacttttatt
    12181 tattttaata acagattcaa caaaactctt tttatctcct aattttaaga taaaatcagg
    12241 atattcttca aattcattga gttttattaa tttgaaagaa gaagatagat ttttaaagtt
    12301 aatgatttta gagttattca ctaatacact tcttttttta aaataaattt cttttttact
    12361 tatatttagt atagttaata tttgtttaag atatattatt atatcttctg gagttctatc
    12421 aaatttgagt tcaaaatttt catcttcaaa gtagggaata taatataaag gtgttttgag
    12481 agcaggtaat ttattatata attcttcaag aatatcgata tttttagggg agttaaagaa
    12541 aaagcattta catacgttca ttaaatccac agcatctgaa agtgagttat gtttaatatc
    12601 tccttctaca gaaaaaattt ttttcatatt cagtaaagat atttgcttag ataagattct
    12661 attattgtat gtaatatgtt gagatataaa aggttgaatg tcaatcatca tattaaataa
    12721 ctctaagcat ttacctgtat atttatatac tctaaatgaa gttagaaggc cagttatatc
    12781 aaaatcaccc caattatata ttgtaacatc atcaaattta caaaaccatt tataaaaatc
    12841 atccataaca tataaaagat taggagcatt attgatatct agttggttca atttggttaa
    12901 atttttacat ttatttgaaa gtattttatt gtattttggc ttaactaaag agtaataatt
    12961 atctattgta ttaaattcgt tatcaactaa aactccacca atagaaatta attccgcacc
    13021 attatattct tttggtttat ttttattatc atctagtata ttaaattcaa agtctataaa
    13081 taacttgtat ttcataaatc taaagcacat cctcaggtaa attctttatt gagcctaagc
    13141 atcataagaa tcaatagata taatgactct aaacatcaaa ggttcattac aacttttatt
    13201 tatttcataa tttaattcaa ataaatcttt taagatataa tttataagta ttctttccca
    13261 acccattttt aaattaactt tagagtctat taatatattt tctatctttt taaatatttc
    13321 tatatttgct ggtattatac tgagctcaat attactttta aacgggttag actgtaaatc
    13381 tgttataagt atatttttta attcctctgt aagttcagaa attaaactat cacctatgta
    13441 tttttttatg atttcctctc taatttcttt taaatttagc aatattagta cctgctactt
    13501 acatagtagc ttttcctttc cttttaatac tattattcat ttttgaatct tatttagata
    13561 tattttaaga ttaaaagtct ttagctatat aattttttac ccatttttaa cttatattaa
    13621 catattacag gcttatatct ccaccctgct tacattgagg atggagtata ttgcctattt
    13681 tgataaaaat gataggttgt tatttgccta ttcctttttc tgataatttt tctaacatat
    13741 ctttggtcat tttatctaaa tcataactaa acttaaagtt ccattctttt actgcactac
    13801 tactgtctag agagttaggc caagaatcag ctatactttg tcttacaggg tctacatcat
    13861 attctatcac aaaatcagga atatattttt ttatagaatc agctatttct tcaggagaaa
    13921 agctcatagc agtaatatta aaagcatttc tatggatgag tttatccgct ggagcttgga
    13981 ttaaatccac tattgattga agtgcatcag gcatatacat catatccatt tttgtacctt
    14041 ctgctatgta agatttatat ctcttatttt ttaatgcctc ataatatata tcaactgcat
    14101 aatctgtagt tcctccacca ggaggcgtaa cataagaaat aagacctgga aatctaacac
    14161 ctctagtgtc tactccaaat tttgagtgat aataatcaca tagtaattct ccagaaactt
    14221 tagtcacacc atacatagta ttaggtcttt gtaatgtatc ttgaggagtc atattttttg
    14281 gagaattttc accaaaagca gcaattgaac taggtgtaaa aaatttacaa tccaattctt
    14341 tggctatttc aaggccattt attaatccat tcatatttaa gttccaagct tctagaggtt
    14401 tactttcagc aactgcagaa agtaaagatg ctagatgaat tatagtatct acatcatatt
    14461 tttttgcaat ttcaaaaaaa cgattcttat ctgtaacatc taatatctca aatataccag
    14521 attcacatac tggattacct tcttttactc tccttgaact agcgattaca ttttgttctc
    14581 catactcatt tctaagcttt attgttaatt ctgaacctat ttgtcctaat gcacctgtta
    14641 taagtatttt tttcaatttt acaacctcct aagggtttaa tttatgtagt actacttatt
    14701 tttattttag caaatctttt gtttaaatac aaagaattaa agataataat atacgactta
    14761 attgaatgaa gtgcagtaaa ttcctaaaaa tttaaagttg agatataatg gtctattgta
    14821 taacaataaa agactagatt aaattattat atagattgtg tgactaagtc acagaaagta
    14881 tagttaattt aatatataat aaaagcatat caagtaaagc tttaaattaa agcaacttta
    14941 taaataaaaa gtaatataaa ttgataaaat tataaattta tttatagtga atataggttg
    15001 gattttatag atacaaaaat agtatatatg atatgtagac cattagcatg tttaaagtag
    15061 caaaacatat aaaataaaat ttgaaaggaa gtataaaaat gacaagacca tcaatatatc
    15121 atagccaagg atacacttgt gcagaggcat taataaagtc ttataatgag gaacacaaca
    15181 cagatatacc aatctcaata ggaagtggta tgggggttgg aatgaatgtt ggaagtgttt
    15241 gtggagctgt aaatgctgct gttgttataa tagggtattt aaatgggcga aatagtaatt
    15301 tagatgaaaa tatagcaagg aagtattcaa gagagctatt gaataaagta agaaataaat
    15361 acagctcaga aatatgtgta tctcttaaaa aaaataaagt aacttgtgaa gaaataataa
    15421 atttcacata tgatgctcta aatgatatgc taaaaaatca aaaataattc taagaaacaa
    15481 gtattttaca ttcgatagaa tacttgtttt tttatgatat ttttaatagg tattagttta
    15541 ttataatttt taaatcaatt ttattatatt ttaattgaaa taatctactt tgaaaattac
    15601 taactgacaa aagaatatga ttatagtata gaaaaaatgt aaattattta atattaagtg
    15661 agagtatatg cttacctata taaaatcgta taaattaatg gctaaattta taaattataa
    15721 agaaatatat aagaaaacaa aagaattaat tagtataata taaagttaaa aagtgaaaat
    15781 ttatataatt tatttataaa gtaaagaaaa aatagaaatt tgtaatgaaa taaaaagttt
    15841 atgacataat atggtataat tagtaaaaat atagagattg gaggaattgc tttgtttata
    15901 gatgaagaat tagaagggta tatattaaca tgtaaaatat ctgaagactt taaaaatata
    15961 cctgaatata gtgatgaaga gttttatgtt acagtctata aagatgaaag ttctgactct
    16021 gggtactatg ctttattaga aaataaagaa gaaagagttg tatgggatgg agaagttgtt
    16081 gccaataata tttttaataa cctttggatt gtagtaaata aggttaaaac tggataatag
    16141 tctaattata tagtatttgt aatattttaa atgaattttt acatatttga gatgagtaaa
    16201 taacaaagat tattcgatac tggaggagta attcaatgga atatagttat agtaagatga
    16261 acttaaaaaa aggggatatt gtagaggtaa atttagagaa acaagccaat gtaatattgt
    16321 tagaccatat aaattatgtg aaatttaaaa atcaaagaaa ttatgattac tatggtggat
    16381 ttgcaaagaa aaatccatgt agaatgagag ttcctaatac tggaacatgg tatctagtag
    16441 taaatcaaga tggaaatagt ggaatagtaa acttttcaat caatacaatt caaaattaat
    16501 tttagaatat tggatattct tactttttgt actttttata tagttaaaat aaaattaata
    16561 agcaattatt ataaaataat gtgggtgcct caaaatgaat tttataattc acgagacact
    16621 cttttttgta taaactcaaa tatactttat catttcaaca atgaaaaaga ggcgtatctg
    16681 tgttttgaga tagcctcatt tatcatatat catatataga attttaatta ttcttaacta
    16741 aaattttttc cataggttat ctgtacaatt aaaatattta ttgttagcat acagctccac
    16801 ctgtaaggtg taaaagagcc tctagtatct cttcttttct ttccaaaact tcatctgata
    16861 aaagcatttc tataaattta tcagcaccaa ttctatcgat agttattcca aaacgttcac
    16921 ctgtgttacc ctgttctcta aataaaagaa ttgctttttc aattaaagtc ataagttcct
    16981 cttttgaaaa taatctatca atctgtgttc caggacgaac tgattttccc catttccctc
    17041 ctatatagac tttataacca gattcttttt cttcaatact atcaaaatta caactttcta
    17101 tacacttacc acagttatta catagattac tatctatttc aagtttacct ttatctgtta
    17161 atttagctgc tttaacagga cagacctcta caacagcaca ttttttacaa ccaacacaaa
    17221 gctctgaatc atagtcaggt acacgttgac caacaattcc aagatcgttt aggtcaggtt
    17281 taatacagtt attagggcat ccaccaacac caattttgaa cttatgaggt agttttacat
    17341 cataccaatt tttgtaaaat tcttcgtgta tttcagcagc aagtgcctgt gtatcagcta
    17401 gaccatgaac acaaacagta cctttacaag ccacaacagg acgaaccctt gatccagttc
    17461 cacctgttat tagattttcg ctagcaataa attcacttag agcttcaata tcttcaaatt
    17521 ttacaccagg taattctact gttagtctag tagtaaatgc taactgaccg tttccgaatt
    17581 tttcagcagc ttctgcaatt ttttttgctt gtgatgcatt tattacacca tttacagtta
    17641 ttatacgtgc tgcaaaatgt tctccatccc tgcttggtag aaaacctcta ccttttactt
    17701 cctttttttg ttctgctgta acattactca tatttactcc tccattacct taagatttgg
    17761 ataaaatagt attccacctt caagaacttt cgtatttgta tagccaaagc gtcttaagcg
    17821 attttgcgcc atatagctat ttttaccttt agcacatata agaagaattt tttcatcctt
    17881 agcaagacct tcaatttctc cattaatttc accaacagga atataacgta aactaggaat
    17941 agaaggagct tttgaaacat caagtttagt ccaactgtca aaatcctcaa tttcgtcaag
    18001 taaaacacta tcaagttctc cattaagttt attttgtaaa acatttactg ccactacaaa
    18061 agggtgaata gctgttgaaa aaggtggtgc atatgcaagg tccatacttt ctaatgaata
    18121 aaggtcagcg cctaaagtta ttgcagtagc agcgatatct actattttat caaccgctcc
    18181 aggtcccata acttgaacac ctaataattt tctagtattt ttttcagcaa ccattcttat
    18241 aataaaatta gatgcacctg gataataatg agctttatca tcggtagcta tggttacaga
    18301 gcaaacatta taaccttctt tttcagctat ttctttactt agacctgttt ttcctgcatt
    18361 gagctcaggt aattttacta ctgttgttcc aagaacacca ttgtaagttt tagattttcc
    18421 agatatattt tgtgcgcaaa ttctaccctc atgatttgca gatgacccca taggtgacca
    18481 tgtaggttta tttgttaaag aattttttac aaaagcacag tctccaacta cgtatatatc
    18541 tttatcattt gtaagcatat attcatctgc aataattgta ttattagggg caaattctaa
    18601 acctgtgtct tttagaaaac ctgtgttagg acggattcca actgacataa ccactaaatc
    18661 tgttttaata gctctatttt tagtacgaag tttttcaact ttattttcac cttcaatacc
    18721 tacaacctgg tcacctgtaa aaatcattat gcctttatca gccatatgat tttcaacgta
    18781 ttcagcaaaa tcagtatcaa atccaggcat aacatgttca gccatatcaa caacacttac
    18841 acgtataccc attgcagaaa gattttcagc aatttcaaga ccaatgaaac ctccaccaat
    18901 aacaacagct ctcttaatac cgttttcaat agaatctctt agttttatag catcatttgg
    18961 agtacgcata aagaatactc caggtaaatc tattccaggt attggtggtt ttattgggtc
    19021 tgcccctgta gcaattacaa gtttgtcata gcttagattt tctttttctc ctgttgaaag
    19081 cgttttcaaa gttacttgtt ttgcatttct atcaatagac gtaacttcaa ctccacaacg
    19141 aacttctgct cctgttagtt tagaaaaact ttcaggtgta tttacgatta aagatgattt
    19201 atcttcaatt atcttaccaa cgtaatatgg aagaccacaa cctgcataag aaatatcatc
    19261 acctttattt agtattgtaa cagagcaatt atcacccatt tcacgtttta tttttgcagc
    19321 agtttttgtt ccagcagcaa ctccacctat aattaatact ttcacaatat atcacactcc
    19381 aatctacttt ataactctat aataaaatta tacttcttga caatatattt gtaaaatact
    19441 aaaatattaa taaaatcata agcatttact aatgtttgct aaggttgtga taatatgaca
    19501 attcgtagtc ttgaaatctt tgttaaggtt gctgaatgtg gtaaaatgag tgaagtagca
    19561 agaaatatgt atattaccca gtcatcagtt agccaagcta tttcagaaat agaaaaagag
    19621 tatggtgtta agttatttga tagaatttca aaaaaattat atttaactga ggcagggaaa
    19681 aaacttcttg gatatgggag gcatctttta gctgtaaatg aagaaatgaa tgattgtatg
    19741 aagcattgtg caaaaaatat ccgtataaga gttggggcaa cagtaactgt tggtacatgt
    19801 gtaataagcc cgataatgtt agaattatac aaggtaaatc ctcttataga acctgaagta
    19861 tttgtagaag atacaagact gattgcaaaa aaattactta atagtgaatt agatattgcg
    19921 attgtagaag gaaaaattaa gcacccagat attgttacaa aaagcattat taatgataat
    19981 cttgtactta tatgttcaca caagcatgag ttctacaaaa gagactctat aaaagtttca
    20041 gaactttcaa atcaaccatt aattatgcgt gaattgggaa gtggtacaag agcacaatta
    20101 gaaaagcaat taaaagaatt aaaaatccca atgaatatta gatggtcatg ttataactct
    20161 gaagctatat taagagcagt tgtagataat tttggcattg cagttatatc tgaattactt
    20221 attgaggatt acttaaaaaa gcatcttttg tgggcttgtg atattgaagg tattaattta
    20281 cataggacat tcgatattgc atatcataga agcaagtttt ttacagaaaa tatttcagca
    20341 ttttttgata tttcagtaga atatgggaaa aaacaagcga gaaagaagag tagaagtgta
    20401 aacagtttat aatatatcta aataaaaata agagtatatc aatatactct tatttttatt
    20461 tagatatatt agcctatatt aacgccaaaa tttttacaca atcctgcaag tccatcctca
    20521 aatccagaac ctaaagcatt aaatttccac tctccattat gtctatatag ttctgccaca
    20581 actattgctg tttctatgct aaaatcttca cccaattcat atttaataag ttcctcatta
    20641 gtttcttcat tatatattct tatatatgaa ttttcaactt gtccgaaatt ttgtcttctt
    20701 gtaattgctt catttatagt aacactaaat gatattttag caatattttg aggtatttta
    20761 gataagtcta catttatttg ttcatcatca ccatcaccaa cacctgttct attatcaccc
    20821 atatattcaa cagcttcaga agcgtgtttt aaattattat agaatataaa gtctccatca
    20881 ttcgttactt ttccatcagt tccagttaaa aatgcagagg catctaaatc gaaatcaaat
    20941 ccaccatcat atttattaat atcccatcct agtcctacta ttactttttt tagaccaggg
    21001 ttactttttg ttaaacttac tttttgtcct tttgctaaag ttatacccat ttaaaccaac
    21061 tcctcattat aaatttttta ttgtaattat tacttatatg tattaattaa ttcacgaagc
    21121 tcttcatttt gaccaattcc taaagcatta aatttccatt cttcatttct acgataaatt
    21181 tctcctgcca aaactgttac tttaccagaa aagtcttctt gaagattata tttaaataat
    21241 tcttgcttgg aatttgaatc aattaatctt ataaaagagt tgttcatttg accaaaatct
    21301 tggtctcttt ttttagcttt gtatatagaa actccaaaaa ctattttatg tacatattca
    21361 ggtatgtctt ctaaattaac aattatttgt tcatcatcac cttcaccttt tccagttaag
    21421 ttatctccag tgtgtataat agctttagaa gggtgcttaa ggtttccaaa ataaaccaag
    21481 tcacctctaa cattcatttt atcttggtta gtcaatgcta ttgcaaatgc atctaggtca
    21541 taattttttt tacccaattt attcatatcc catcctaagc ctactactag attttttaca
    21601 ggattattat cttttactaa gctaactctt tgtccttttt gtaaactaac actcatttta
    21661 agttctcctt tttatatttt tagttttatt gatggtatca agtataagaa ccatattagc
    21721 tatattatat acgtatttag gctaagttgg ctatatttat aaattattta ttatataact
    21781 acatgaatat tttataattt aaacatattg acattatatg ttttaaatta ttttgtagtt
    21841 ttataatatt taaatttgta tttgattgtt ataaagtaaa gtaagtaata aagttagagt
    21901 caataattct aaaatttcta agcatactat ctaaatgaga acggatttgg aaatacttat
    21961 ataaaacaat aattgataca tttaattttt atcttaaaaa caacaattat aatatataaa
    22021 tagcaagtat aatataacat ataaaaagtt gaatttgtat atgttaatta tacttgctat
    22081 ttatttgtta gttattctat ttttttaaat ccattaccta aagcttcatg tatatctgta
    22141 attataataa aagcattagg gtcgacattt tttactaatt tttttaattc gacaacttct
    22201 ttcttttcaa ctactactaa aagtacattt ttattttctc cagtatatgc accttctcct
    22261 tttagaatag ttgcacctct atctaaatct tccattattt ttttacttat atcttttgaa
    22321 aggtcagata taatagtgaa tgatttggaa taattaaatc cttcaataag caagtcacta
    22381 acttttacta aaatgtataa agccacagtt gaataaagtg caatttcaac ctgtctattt
    22441 actatacctg ataaaacaac tacaacgcag tctacaatac ccattaaaac aggtatacta
    22501 aatgtaggaa aatatttatt tagtaggagt gccattaaat cagttccacc tgtagagcca
    22561 tttattctaa aaataagtcc ttgaccaact cccattaaaa tagaaccaga tataattgca
    22621 agatacatat catttgttat atctaatgta gccatatttg cagtaagctt aagtgctatg
    22681 gtaagaaaaa ttattcctaa aaccgtttta aaacaatctt tttttgaaag tattttgtaa
    22741 gcaaatatga ataatggaac atttaaaagt aaattgacaa tccaaagttc tacaccgaat
    22801 aatgaattta aaacaactcc aagtcctgtt ataccaccag cagcgattgc atgtggatta
    22861 aaaaataaat taagagaaat ggccattaat atacagccta caattaatat taaaatttct
    22921 gaaaaagtta ttctatcttt tttcaataac atcactcctt atatatagat tataatatat
    22981 attatatagt ttttccaatt tttaataaaa gaaataaaaa tatattataa aaacaatttg
    23041 attggaattt tcagaaaatt aatgctataa ttaaaagtaa atttaaaggg aggttataaa
    23101 atggctaaat taactctaga acatataaaa ggaaatacat attatattcc actccctaca
    23161 atagtaggtg tatacgtaga tggtaaagat gcaattttaa ttgacagtgg aaataataag
    23221 gatacagcta gacaagtttt aagattatta gaagaacata atttaagtcc taaattaata
    23281 ataaacactc attcaaatgc agaccatata ggaggaaatg catatttgaa gaatcaaaca
    23341 aaatgcaaga ttgctacgac taaaattgaa ggatatttta cagaaaatcc aatattagaa
    23401 tcagcatttt tatatggtgg ctatccaagt aaagcactga agaataaatt tttattagca
    23461 aaggaaagtg aagttgatta tattatacct tcaaatggca aaattgtaga tacagaactt
    23521 gaagcgattt ctcttccagg tcattatttt gaaatgattg gtgttagaac tccagataat
    23581 gttttgtttg ttgcagatag tcttacacca gagaatataa ttactaaata tcattttttc
    23641 ttcctactgg atatagattc acagtttaag acactagaaa aattgagaat gttagaggca
    23701 gatttctttg ttccaagtca ctctgtcaaa actacagata taaaaagttt gattaatatt
    23761 aataagaaga agatggaaga aataatagat aatattaaaa aggtttgtta tgagccagtt
    23821 atgattgatg aagttattga aaaaatgtgt gatttgtaca atgtcaagct tgatgctaat
    23881 caatatgtgt tggttggaag tacaatacgt tcttatataa cttatttata tgagaataat
    23941 atggttgaat atatatttga tggtggtaag atgatgataa aagctgtgta aatagtaata
    24001 attttcaaat tatatgatga aattgtttta gtatgactgt tatttgaaaa gtaatataaa
    24061 aaaatttata taaataagct aagataattg atataaagtt actgataatt ttaaggtaat
    24121 atatacgtta ctataatatt atgttattat ttgtaaataa ggggataatt tataagcaaa
    24181 ttaaagacct taatttacag gaggaatagt gtatattatg aataaaaaat tcaaaaaatt
    24241 cagtaaaaaa ctaagtatat taattttagt tttgactatg tttcttttta ataatttaac
    24301 tgcaaatgca cagattaaag aagattcaat aataggaatt gatagatatg aaacagcagg
    24361 acttatagca gatagacaaa cttatgatac tgtaatatta gttaatggag ataaaaattt
    24421 atctgatggg ctttcatcaa gtggattagc tggagctatt aacgcaccaa tacttttgac
    24481 taaaaaaagt gaaataccaa aagctacttt aaatagacta gataataaga gtttaaatgt
    24541 tgtaaaaaaa gtatatataa ttggtggtta taatactatt gaaaattcag tagaaaaaga
    24601 tataaaaaga aaaggtattc aagtggaaag aataaatggt aacaatagaa ttgaaactag
    24661 ttataatgta gctaaaaaaa taaatgaagt aagtagtgta aaagaggtaa tgcttacaaa
    24721 tggatttgta ggagaggctg atgctatgag tatagcacct gtagttgcaa aaaataaagg
    24781 agctataata cttacagatg ggaaatcagt tccatttaag actgaaggtt taaatgttta
    24841 cgctataggt ggcaaatctg cgataaagga ggatttagta aatgaaacta aagcaactag
    24901 aatcggagga aatgatagat ttgagaccaa taaaaaggta atggaaaagt tttataatgg
    24961 agcgacagat ttttatataa caaatggata tcaattagta gatgcactaa cattatctcc
    25021 tttagccaaa gaaaaaccaa tcgttttagt tgctgatgga agtaataaag gtattttaaa
    25081 aggagctaaa agtataacaa aagttggagg tattgatgcc aatatatata aacagtgttt
    25141 agatatgatt aaatataata atatggatgt gactccaaat attttaaaac acttaacttc
    25201 agttgaagga aatgaagttt ctgaaatact tatagaatca gataatttag gtgtggttgt
    25261 tgaaaagacg aataccaata aatttgagtt tgattacgta agtgtaacta atgaaaaaaa
    25321 ttgtactttt tctgtatata aagaaaattc ttctaataat gtaaaaaatg gaaagctagt
    25381 tgtaagtgct aagaaaaaaa tagataagaa agatagtgat ttgcaagata tgaatggcga
    25441 caatatgata aatgcaaata aagataggat ggtaaatgtg ataaaaattg gagttcccga
    25501 taaaatgtat tctaatttta aaatagatgt tgaaagtggt tcagtagaac tttataatat
    25561 taaaggagga gctactgttg atgtcaatga cggaattgct aacattgttg ataacaatgt
    25621 gacaaatcct ttcaatataa atactaatag tgggatttca ggtgtaacag ctgaaactat
    25681 atcatctgag ataaaattta gagcaaacaa tggaattgta agtgtaacag ctacaaatat
    25741 aaatggcaat ataagtttat ttggaagcga taataaaggt acctttgatg gaatatttaa
    25801 attaaatctg aaaaaagaac catcaaattt acacttgaag ttagttggaa atgggataaa
    25861 taaattgcca gaaggttggt ctaaagatta tattttagga aatggacaac caattattga
    25921 agttaaaaat aatggcataa ataatatatc aattggagaa taaaaacata tgaaaataaa
    25981 gtttatatag ttttaaaaat tatagaattt taaaatattt atatatattc tttaaataaa
    26041 aaattatttt ttaagtgata attaagtatt tatcgataag gctatggttg taaaaatcat
    26101 agccttattt ttatattata aataaattag agtatttatc aattcatagt agataaaatt
    26161 gaaattaaat ataacaacaa aaaatgaaaa ttacaattaa tttaatgtta aagactcaat
    26221 tatttggatg tggaatggat agtacaagta gtatataaaa agtattgact ggacaaataa
    26281 ctatatttta ttttaaatat ataatataat gtaataaaat atatcaaatg tagaaggtga
    26341 taacctatga aaaaaataac aataaatgat attgctaact tggcaggagt atctaaaagt
    26401 actgtatcaa gatatctaaa taataaagat atcagtgatt ctactaaaga gaaaataaag
    26461 acaataatag atgaatatgg atatgagccg aatgcatttg ctcaaagttt gagagctaaa
    26521 aaaacatact ttattggtat tataacaccg tgtttagatt cttttgtaaa atctaaaatt
    26581 atgatggcaa tagatgaaga actcaaagaa ttaaaatata catcactaat tattaatact
    26641 aatagaaaaa taaggtcaga aatagatagt atatcaaagt tagctagtct aaaagttgat
    26701 ggaataatac taattggtac cgaaataact aaagaacata agaatgaaat tgaaaagtta
    26761 gatataccaa tggttgtagt tggacaaaaa gttgatggta tcaatagcat agtgaatgat
    26821 gattatggag caggatataa aatgggtcaa tatattgcta ataaaggtta caaaaacatt
    26881 gtatatttag gtgttgatga aagtgatata tcagttggtt taaatagaaa aaatggagta
    26941 cttaatgggt taaaagataa agggtatgat gcaaaagtat tttatactga ctttgaccaa
    27001 gaaacgtcta tacaaagaag tggagaaatg ctagaaagtg aaaatccaga tataataata
    27061 tgtgcaactg ataatatagc aatagcaaca atgaaagaaa tcaataagag aggtaaaaat
    27121 ataccacaag atatatctgt agctggattt gggggatatg atgtattgtc tattataagc
    27181 cctaaactta caacaataaa gtttgaaaat aaaaatgcag gtaaagtagc agcaaatacg
    27241 atagtaaact taatacaaga aagaaaagaa ccactattaa aggagattaa atttgaatta
    27301 atagaaggtg aaagtacaat aaataaaaat taagatacac attacatata ttagtaatgt
    27361 gtattttttt actaaaaaaa ctataattct aaaaattagg aaaacttttt tgaaagaaat
    27421 attgcatctg aaataaattt atgctaatct ttaattaaac cggtttcgaa accggtttaa
    27481 ttaagcgaga gaatagcaca atgagtgcaa aaataactga ttgtaacaaa gtatcaaagt
    27541 aattattaga gtacatagga aataaacaaa atataaaagg tgtagcacat tgtgtaacaa
    27601 gattaagaat tgttttagat agtaataata aagcaaatat aaaattataa aagaaaagga
    27661 ataaaaatat gtacaaagag cctaaatata gaaccatatt agaatcgaca aaagaagaat
    27721 taaataaatt aagaaatata tctttaaatg ataaatataa accactattt catatacatc
    27781 cacaacatgg actacttaat gatccaaatg gattagcata ttataatggt aagtaccatg
    27841 tattttatca atggtatcca tatgatgcaa ctcatggaat gaagcattgg gcttatgtaa
    27901 gttctgatga ttttgtaaac tggaatagag aagatgtagc attaatacca atcgaaagtt
    27961 atgaatctca tggagcatat tcaggtaatg cgatagaggt agatggaaaa ttgcatatgt
    28021 attatacagg gaatataaaa tatagtgcag aagatagata tgcatatcaa aacttagcta
    28081 taatgaacaa ggatggtaaa ataactaaat atgaaaataa tccaatagta agtgaaatac
    28141 caaaaggata tacaggacat gtaagagacc caaaagtatt taaaagaaag gataaatact
    28201 ttatgttact tggagcacaa acaagtgata aaaaaggagt tataatagta tatgaatcta
    28261 aaaactctat agattggaat tttaaaggag aattaaatgt aaaaaatata gatgaagatt
    28321 ttggttacat gtgggaatgt ccagattata ttaatataga tgaaaaagat atattaatat
    28381 tttcgccaca aggagtagaa cctaaaggat ttgattatca aaatatatat aatgtagtat
    28441 atgctattgg taatatggat ttagataatt taacatttga aatagataca atgaaagaac
    28501 tggaaaaagg atttgatttc tatgctccac aaacatttat aaaggactca caaataatac
    28561 tatttgcatg ggctggaatg ggagaagttt tataccctac agataaaaac aaatgggcac
    28621 attgtctaac tgttccaaga aaattaaata taaaaaataa caagctattg caaatgcctg
    28681 tagatgaatt aattaaatta agatatgatg aaacaagtgg gcaaaatact ataaagaata
    28741 atatcaatat tatagaaaat gatgaaaatg tatatgagct taatattaat ataaaaaata
    28801 ttgacagcaa taaatttggg ctggaattat tttcatcaca agatgaaggt gtaaaattag
    28861 aatttaacaa attaggaaac attgtaactt tagacagaag caactttaaa aaagttttcg
    28921 gtgttgaata tggaacaaat agaaaagaat atataaatat tgatgaaaat attaatatca
    28981 aagtactagc ggatagaagt gttttagaaa tttttataaa tgatggagaa gtagtattta
    29041 ctagtagaat atttgctaaa gaaaattcta atcaaataag ggtttatagt gataaaatag
    29101 tagagtatga gtatactaaa tttaaattaa agcaaggtat tgaattataa aaacacatta
    29161 taaggggtag aaaagatgaa aaaagtaatt agtataggag aagctttaat agactttata
    29221 cctaatcaaa atggttgtaa attaaaaaat gtatcagaat ttagaagagt agcaggagga
    29281 gctccagcaa atgttagtgt tgttgtagca aagcttggag gaaaatcaag ttttatatct
    29341 aagttaggaa aagatgcatt tggtgattat ataatagatg tattaaatga agtaaatgta
    29401 aatactgatt atgtattgag aacaagtaaa gcaaatacag gacttgcttt tgtatcatta
    29461 aaagaagatg gtaatcgtga tttctcattt tatagaaatc caagtgcaga tatgctttta
    29521 gaagctgatg aggttaaaaa agagtggttt aataattgtc atatcttaca tttttgttca
    29581 gtagatttaa tagatagtcc aatgaaatta gcacataaaa aagcaataga atacgcactt
    29641 gaaagtaata gtataataag ttttgaccct aatataagat tacctttatg ggatagtgag
    29701 caatcttgta aaaaggcaat atcagaattt ttaccttttg ctcatattgt taagatatct
    29761 gatgaagaat tagaatttat gacaggagaa aatgatatag aaaaatcatt acataaactc
    29821 tttgtgggga atgttgaact agtattatat acaaaaggaa aagatggagt agatgcatac
    29881 actaaaaaag taaaaggtat gtgtaaaggg gttaaagtaa atgcaataga tacaaccaga
    29941 gcaggagatt cttatatagg ttcattttta tacaccttat tgtataaaca aataacattg
    30001 aatgatataa aagaaatgaa acaagaaacg ttaaatgagt atttagaatt ttctaattat
    30061 tatgcagctc gtagtacaac tattaaaggt gcgataagtt catatgcaac aaaggaagaa
    30121 ataactgaat ttataaaaaa tttatagtag gaatgagtaa taggttttga aggaagtaac
    30181 atgtaaagag tttttaagga tgtttactat gaaaataatt aacatataaa aagcaataaa
    30241 gaggctgtct caaa
//
LOCUS       DACTZW010000045        29972 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.045, whole genome shotgun sequence.
ACCESSION   DACTZW010000045 DACTZW010000000
VERSION     DACTZW010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 29972)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29972)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29972
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.045"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            <1..171
                     /locus_tag="JAM15_10950"
     CDS             <1..171
                     /locus_tag="JAM15_10950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAT6798771.1"
                     /translation="ASSQICNKCGYKNEEVKDLNIREWICPSCNETHDRDINASINIL
                     KEGLRLITTQNK"
     gene            290..808
                     /locus_tag="JAM15_10955"
                     /pseudo
     CDS             290..808
                     /locus_tag="JAM15_10955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860778.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
     gene            835..2202
                     /gene="rlmD"
                     /locus_tag="JAM15_10960"
     CDS             835..2202
                     /gene="rlmD"
                     /locus_tag="JAM15_10960"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HAT6798772.1"
                     /translation="MSVKKKDVIEFEVDKMEFGGTSLSQVGDRVIHMKGGISGQKVRA
                     GVKKVRSKKAEVKMIELLENSPLETEETCKHFRECGGCTLLSVPYEKQLEIKEKQVMD
                     LFLKQDLFGFQFLGIEGSPENKYYRNKMEYTFGDEVKNGPLTLGLHKKGKHIDIQTVE
                     ECMLVDEDFSKILVSSVEFFNEKKLPYYRTMNHKGYLRHLVVRKGIHTNEIMVNIVTS
                     SQEDFDMNEFKDMLLGIDLKAELVGVLHTINDGLADAVQCDELRVLYGRDYIQEEILG
                     LKFKISPFSFFQTNTKGAEVLYSIARDFIGDYNDKVVFDLYSGTGSIGQVMAGAAKKV
                     YGIEIVEEAVVAANENAKLNGLTNCEFIAGDVAKVVKDLKDKPDLIIVDPPRPGIHKD
                     AIRDICGFGAKEIVYISCNPKSLVVDLVDFKGYGYEIKMVKCMDMFPNTPHVETIVLI
                     QRKTM"
     gene            complement(2420..3172)
                     /locus_tag="JAM15_10965"
     CDS             complement(2420..3172)
                     /locus_tag="JAM15_10965"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798773.1"
                     /translation="MLEIISICLNVITIVLTIYELFWEKSSNSTKQYIQNNIIQQINP
                     KYDIKVSSTPMYKLDNVAIKNARWKSKRITQFAIILIYLSMAINFVNYIKINTIHSVT
                     DFTAIFYIPMRNTMIQLSIILVLLCIIFIVRGWNKQQSIFSNLMSMKYFTLKIVVDTF
                     AIVGLALVDYSLLEKINTNIQNSLYTINLIGWSVLFVFQLLWIQHTVLKIYKLIPLSN
                     TYEEKEKQLFAFVPVYIISILLFGLTIYTKFF"
     gene            3216..6347
                     /locus_tag="JAM15_10970"
                     /pseudo
     CDS             3216..6347
                     /locus_tag="JAM15_10970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006354976.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
     gene            6560..6874
                     /locus_tag="JAM15_10975"
     CDS             6560..6874
                     /locus_tag="JAM15_10975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018597326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAT6798774.1"
                     /translation="MELKHVIPNMEKTFGNLEYAGEGKTEQRRVNGRMTVISRSFNLY
                     SDVQRADDIIVILPASAGEKNFEVEEKVKLINPKITADGYKIGTRGFTNYILSADDMV
                     KA"
     gene            6890..7276
                     /locus_tag="JAM15_10980"
     CDS             6890..7276
                     /locus_tag="JAM15_10980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009203304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAT6798775.1"
                     /translation="MRLANGIIIDKEKTFGVLKFSALRREVHIQNEDGTVSEEIKERT
                     YDLKSRGQGRMIQVSIPASVPLKEFDYNAEVEIINPVADTVATATFQGADVDWYIKAD
                     DIVLKNKGGQPVANPQNHNQQPQGKK"
     gene            7358..7651
                     /locus_tag="JAM15_10985"
     CDS             7358..7651
                     /locus_tag="JAM15_10985"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798776.1"
                     /translation="MRINHNDAISLEHIVRGVFVCDRAGMGGYIDADHFESAPFDAAL
                     IALAPLWQKADFHEIEDFLFKWEQTLRNTDNMSVDIQSYIQELDSLVTLLMQR"
     gene            7741..9147
                     /locus_tag="JAM15_10990"
     CDS             7741..9147
                     /locus_tag="JAM15_10990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009203305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HAT6798777.1"
                     /translation="MRFYNHYKGNRIRASDRSLVVRSMSGQLACLFLLVVLLLNINTL
                     LHTDWNTLSLFQNGSIKLTVTPYMIVSLIVAVLVCGLAAFLYARYQPDRIKQLCHRQK
                     LSRMILENGWYESEQSQDGGFFKDLPASRSKEKITHFPKVYYRLDNGLIHILAEITLG
                     KYQDQLLHLEKKLETGLYCELVSKELKDSFVEYVLLYDTIANRITIDEVQASGGSLRL
                     MKNVYWEYDKLPHMLIAGGTGGGKTYFILTVIEALLCTNAELYVLDPKNADLADLSAV
                     MPEVYYQKEKITDCIDRFYDGMMERSEAMKLMEGYKTGENYAYLGLPPHFLIFDEYVA
                     FMEMLTTKENAAVLNKLKQIVMLGRQAGYFLILACQRPDAKYLGDGIRDQFNFRVALG
                     RMSELGYSMMFGEVDKDFFLKQIKGRGYVDTGTSVISEFYTPLVPKGHDFLREIGRLM
                     QNRQDGQAACEAKAAGSD"
     gene            9320..10537
                     /locus_tag="JAM15_10995"
     CDS             9320..10537
                     /locus_tag="JAM15_10995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002592297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAT6798778.1"
                     /translation="MEGFLLNDTDWNTDLKEKRLSYGVSQNKLAVAAGITRQYLVKIE
                     SGSAAPSEEIKENLLQALERYNPETPLTMLFDYVRIRFPTTDVRFVVETILKLKLDFM
                     IHEDFGFYSYPEHYYMGDIFVLVSPEQEKGVLLELKGKGCRQFENFLLAQHRSWYDFF
                     TDALCEGGVFKRIDLAINDRVGILDIPELTAKCRNEECISVFRSFKSYRSGELVQSHE
                     ENKSGMGHTLYIGSLKSEVYFCVYEKDFEQFVKYDIPIEETPVKNRFEIRLKNERAYY
                     AVRDLLTYYDAERTAFSIINRYVRFADKDETKRRSEWQTNQRWAWFLGEGRGRLKLTT
                     EPEPYNFQRTLNWLARQVAPTLQVAEKLDQQNNTTIIKDMVKHAKLSDRLEKVLRQLS
                     VTVEEMTVKDKEE"
     gene            10541..10675
                     /locus_tag="JAM15_11000"
     CDS             10541..10675
                     /locus_tag="JAM15_11000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HAT6798779.1"
                     /translation="MWHILFDLLLVSAGMGTGVVLMCILQAGKEADTCLEEMERSNEK
                     "
     gene            10672..10893
                     /locus_tag="JAM15_11005"
     CDS             10672..10893
                     /locus_tag="JAM15_11005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798780.1"
                     /translation="MNFGQNLYNWFLSNAQSLVLMAIVVIGIYLGFKREFSKLIGFLV
                     IALIAVGLVFNAGGVKDVLLNLFNKIIGA"
     gene            10962..12086
                     /locus_tag="JAM15_11010"
     CDS             10962..12086
                     /locus_tag="JAM15_11010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002592294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798781.1"
                     /translation="MKNILVGNGINIQYDNENYTCKNIVLRVLTELDEEDYPCEYIVD
                     NPMLIKSYMGKLFLAAREALDGGLDKYPNCTAERKGLNDFKDRYKSKKKSLRIADIGF
                     EDYYLIHDLLCHKTHTQNPEQYTIRESLKMAYFHSIYNRGKLNLLHKEYSLGLVDYLK
                     SFDNIFTTNYDSNLESATGKKIYHIHGQFDKLSETYNPTSFRNHLNDNPLEGIPNQPE
                     YKHLHSTALSTYCGDYKRYQIKQNILANEALEKMANGYQTMTSIKKDVDTWETEKNQL
                     VVNLGQAIKLKVANPNLRFQEDYYVKEFQAITGELTILGLSPYNDYHIFEMIESAKLL
                     KCKFYYYNESECERIKTLLPNLYRERKLEFLNVQIFWEGL"
     gene            12086..12421
                     /locus_tag="JAM15_11015"
     CDS             12086..12421
                     /locus_tag="JAM15_11015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002592293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798782.1"
                     /translation="MSQVKYTKITRKKLLQSLAAYNLLSHSQQDWRVIIKEFNSLSFS
                     QRNQIIQEEQLREQLLKDKMTTTDEDMYLTCTMVNLNIVASKFDIDPTTVCMCIAPLG
                     KINENILVV"
     gene            12540..13034
                     /locus_tag="JAM15_11020"
     CDS             12540..13034
                     /locus_tag="JAM15_11020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005335613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAT6798783.1"
                     /translation="MRLYILNTTKPYRDDEDEYAGAWFPCPVTFEEIKEKLGVEKEED
                     FEIEDYELPFSLSPDMPLWEINAMCRMVQEIEGTPIGNELSEIQAKWFHNISDFFDHK
                     DEIRHYDVPDSASLAEYLVMEEHRFGELPPELAKHIDFISYGHELEQSDEYLFTTSGV
                     FRYR"
     gene            13058..13543
                     /locus_tag="JAM15_11025"
     CDS             13058..13543
                     /locus_tag="JAM15_11025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015541088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAT6798784.1"
                     /translation="MRVYIANLGKYNEGELIGDWFTPPVDYDEMAERIGLNDRYEEYA
                     IHDYELPFEIDEYTPIEEVNRLCEMVEELDYPLDEVIDDLLCHFCSVEELYDHKDDII
                     QYPCDSMVDVAYHLIDECGVLGEIPDRLRNYIDYEAFARDIDLEGCFIETRYGVFECP
                     Y"
     gene            13656..14045
                     /locus_tag="JAM15_11030"
     CDS             13656..14045
                     /locus_tag="JAM15_11030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAT6798785.1"
                     /translation="MKKIRSYTSIWSVEKVIYAINDFQLPFPITFTQMAWFVVSLFAV
                     IVFAELPPLNMIDGAFLKYFGIPVAVTWFMSQKTFDGKKPYGFLKSSIGYLLRPKVTY
                     AGKAVKLKTELLNTAITAVRSDVYVPH"
     gene            14032..16482
                     /locus_tag="JAM15_11035"
     CDS             14032..16482
                     /locus_tag="JAM15_11035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008817941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAT6798786.1"
                     /translation="MFPIKYIENNLVFNHDGECFAYYELIPYNYSFLSPEEKYMVHDN
                     FRQLIAQNRDGKIHALQISTESSIRQTQERSKKEVTGRLREVACAKIDEQTEALVEMI
                     GENQIDYRFFLGFKLLVNEEEISLKHAGKSAAMTFADFLYEVNHQLMGDFVSMSNDEI
                     ARFQKMEKLLESKISRRFKIRRLEKHDFGYLIEHIYGKTGVAYEDYAYDFPVKKLKKE
                     TLVKRYDLIRPTRCQITENQRYLKMDSEEQTTYAAYFTINNIVGELDFPSSEIFYYQQ
                     QQFTFPVSTSMNVEIVTNKKALTTVRNKKKELKDLDNHAWESNNETSNNVVDALDSVN
                     ELETTLDQSKESMYKLSYVVRVAADSLDELKRRCDEVKDFYDDLNVKLVRPFGDMLGL
                     HGEFLPASKRYINDYIQYVTSDFLAGLGFGATQQLGESDGIYIGYNLDTGRNVYLKPS
                     LAAQGVKGSVTNALAAAFLGSLGGGKSFCNNLIVYYAVLFGGSAVIVDPKSERGNWKE
                     TLPEIAQEINIVNLTSEAKNKGLLDPYVIMKNLKDAESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRSVTHGKRRGLLCVIDELRKEGTPVASNIAEHIESLVDYDFSHLLFSDGAV
                     EQSISLDKQLNIIQVADLVLPDRDTKFEEYTTMELLSVAMLIVISTFALDYIHSDRSI
                     FKMVDLDEAWTFLQVAQGKALSNKLIRAGRSMNAAVYFVTQNSGDVDDEKMKNNIGLK
                     FAFRSTDIGEIKNTLEFFGVDKDDENNQKRLRDLENGQCLFQDLYGRVGVIQIHPVFA
                     DLFHAFDTRPPIQTEETR"
     gene            16488..18704
                     /locus_tag="JAM15_11040"
     CDS             16488..18704
                     /locus_tag="JAM15_11040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002592287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAT6798787.1"
                     /translation="MRKKKIVHYLGIALLVAFATLVFLSVTGTVAHAAGLVDDTVDAA
                     NQYSKYPLENYQLDFYVDSSWDWLPWNWLDGIGKSIQYGLYAITNFVWTVSMYISNAT
                     GYVVQEAYKLDFISDTANAIGTNIQTLAGVNAGGFSTQGFYVGFLLILVLLVGIYVAY
                     TGLIKRETTKAVHAVVNFLVVFVLSASFIAYAPNYITKINDFSSDISSAALSLGTKIT
                     LPNSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYGNSDMEDLGADRVESLLSASPDTDT
                     REDTVIAEIEDKDNANMSVTKTMSRLGTVVFLFLFNIGISVFVFLLTGMMIFSQVLFI
                     IYAMFLPVGFILSMIPSYEGMAKKAITKLFNTIMMRAGITLIITAAFSVSTMFYSISA
                     GYPFFMVAFLQIVTFAGIYFKLGDLMGMFSLQSGDAQQVGRRIFRRPYMLLNRGARRM
                     ERRVGRTLAAGMAGGAAGAAVASGSRKTDTRKSADRQNHTTGSRPSHDTGQSGDTATF
                     GKRAGSKVGAVLDTKQRVKDKAQSVKEQVKDMPTQAGYAVHSVKERAKENVSDFKRGM
                     VEEKTTRQQGRAAKQDSHRQTIAEKRMAMEKAKPTGSAAKGTAPVHERPATMPVSGAT
                     TPQATAAKGAAPKTEPTSKERPAAVPRESYEKPTTTKGREPAAKPQEQRTQVVRESGA
                     RSQTVKEPAKPQVIKEPVPAGTKTIRQTSTQKTNRNIQRNTVKKSSTHTTKKGRKK"
     gene            18701..19705
                     /locus_tag="JAM15_11045"
     CDS             18701..19705
                     /locus_tag="JAM15_11045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005335603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase P60"
                     /protein_id="HAT6798788.1"
                     /translation="MKLRHLALLGGIFTVIISLLLFLFIVTSDDEESGGSSGFDYSGM
                     NLSAEVLKHQPTVEKYAKQYGISDYVNYLLAIMQVESGGTAVDVMQSSESLGLPPNSL
                     GTEQSIEQGCKYFASLLASAKAKGCDINTVVQSYNYGGGFIDYVASHGKKYTFELAVS
                     FAREKSGGVKVTYKNEISIKENGGWRYKYGNMFYVRLVAQYLAVPNFSNATVQTIFNE
                     ALKYQGWTYVFGGDNPNTSFDCSGLVQWCYGKAGISLPRVAQDQYDATQHIPLSQAKA
                     GDLVFFHSTYNAGTYVTHVGIYAGNNRMYHAGNPIGYADLNTSYWQQHIIGAGRVKSN
                     "
     gene            19727..20635
                     /locus_tag="JAM15_11050"
     CDS             19727..20635
                     /locus_tag="JAM15_11050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018596010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAT6798789.1"
                     /translation="MRLKKKEKEAKPNKTKKVRVLKAGTHKKSVIALWLVLIASVSFG
                     VYKNFTAIDMHTVHEKEVIEQRIVDTNKIENFVKDFAKAYYSWGNNKEAIEARTKAIS
                     QFLTKSLQDLNVDTVRSDIPTSSAVNEVKIWNLEQTGTDKYTVLYSVDQTITEGDQTS
                     RNTAAYTVVVHVDGDGNMVITKNPTISRIPAKSSYEPKAAESDGTVDVATTEEVTEFL
                     ETFFKLYPAATDKELSYYVAGNALKPVNTDYLYSELINPLFTMDGDKVKVSVSVKYLD
                     QRTKAAQISQFDLVLAETDGNWKIVK"
     gene            20725..21021
                     /locus_tag="JAM15_11055"
     CDS             20725..21021
                     /locus_tag="JAM15_11055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008879832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2089 domain-containing protein"
                     /protein_id="HAT6798790.1"
                     /translation="MEIDKIPQWILALEQEDATFLKNFVLKSGSLKEVAKLYEVSYPT
                     VRLRLDKLIQKIQISDQQEEEPFSTFIKGLAVDSRIDIETAKIIIEKYKKEKEK"
     gene            21024..21314
                     /locus_tag="JAM15_11060"
     CDS             21024..21314
                     /locus_tag="JAM15_11060"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798791.1"
                     /translation="MLTNIMSILGTIVATLIITGTQKYLSTRRKWQLGSIVPIVSILV
                     MATVLYITKINLSIKVFLPCIIILVLELFIWFDGRKEYKKEEFRKMKAKDIV"
     gene            21342..21629
                     /locus_tag="JAM15_11065"
     CDS             21342..21629
                     /locus_tag="JAM15_11065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798792.1"
                     /translation="MFDLAVGFAIAGILMVVEYFICTRLNNALWGGIIPILILIGTVW
                     IFVSGKVPLEIKTIFPFIICNSIFLGEWDNGRKKYTERKKAEMDKMKAKDI"
     gene            21645..21830
                     /locus_tag="JAM15_11070"
     CDS             21645..21830
                     /locus_tag="JAM15_11070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016283904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAT6798793.1"
                     /translation="MGEEHWVFCPVCHNKTRVKIRGNTILENFPLFCPKCKQETLIDV
                     KNLNISIKEPDTKMQSR"
     gene            complement(21924..22280)
                     /locus_tag="JAM15_11075"
                     /pseudo
     CDS             complement(21924..22280)
                     /locus_tag="JAM15_11075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002592282.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            22459..23265
                     /locus_tag="JAM15_11080"
     CDS             22459..23265
                     /locus_tag="JAM15_11080"
                     /inference="COORDINATES: protein motif:HMM:NF024803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAT6798794.1"
                     /translation="MYRIGEFSKITGLTTQTLRYYDSEKILSPSYRNEENGYRYYSAD
                     DIETAQYISLLRKFNFSIMEIKDVLSNMRTQEDFNDFINEKIVLTENLIIQHKSVIDE
                     MKSYLSLTPLEKKEVENMKYEVNITELSSQLVASIRFKGKYCEICEYFTKVFECADEK
                     VCGIPFTCYYNLEFAETADIEVCVPVSSSVFGNGIQTKTIEGVRTIGVKHIGAYEILG
                     MAYKSLFDYANENNLDYIAPIIEFYDKSMGYTLKGNPDKYETRIYLPIKK"
     gene            23737..24153
                     /locus_tag="JAM15_11085"
     CDS             23737..24153
                     /locus_tag="JAM15_11085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002592281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAT6798795.1"
                     /translation="MKPSSFENAIRLQFDCLARKVVGTTVKDYNRELGRRAKRETPFC
                     ELPEMELNHIGTYDEYSVEFTAFDVFGNEVRIYDEQLCEAIKELNERRRNILLMSYFL
                     EMTDAEIAEVMEMERFSVCRNRLHTLKLIRDMYEEE"
     gene            24157..24396
                     /locus_tag="JAM15_11090"
     CDS             24157..24396
                     /locus_tag="JAM15_11090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005363195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAT6798796.1"
                     /translation="MTKSTKKCPLFSTISSAADGDEVAIGKILNHYDAYISKASLRPF
                     YDEHGNMYIVVDMELKGRIRAALIEAILGFEIKVK"
     gene            24715..24858
                     /locus_tag="JAM15_11095"
     CDS             24715..24858
                     /locus_tag="JAM15_11095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAT6798797.1"
                     /translation="MNNLIRYSMQIAMLKQLLARKLISEREYTLVKQRLMKDYKVLSD
                     ITA"
     gene            24922..26670
                     /locus_tag="JAM15_11100"
     CDS             24922..26670
                     /locus_tag="JAM15_11100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAT6798798.1"
                     /translation="MQEVEVIKARNVLSKQARGKAIERLRVAAYCRVSTDSEDQLNSY
                     KSQVQYYTDMIKKNKEWVLVDIYADEAITGTQVIKREDFQRMINDCMNGDIDMVITKS
                     ISRFARNTLDTLKYVRMLKERNIAVYFEDEKINTLTMDGELLLVVLSSVAQQEVENIS
                     ANVKKGLKMKMKRGELVGFQGCLGYDYHPEDKTITVNKEEAEIVRYIFNRYVEGAGGS
                     VIGQELENLGYKTKYGSSTWAPSTVIGIIKNEKYKGDILLGKTFTVDPISKRRLENMG
                     EEDKFYMKDHHEPIISEEVFEKAQEILNRRNKNRTTVGNGKREKYSRKYAFSCMLECG
                     FCGSTLSRRNWHSSSEYSKVIWQCVTATKKGKKFCPDSKGIPETAIEEAFIESYRLLC
                     DNNKDVLDEFLQRLDDTLSNSTVNKQLSKIEKEISAVEGKKNKLVDMRLEDSIDKDTY
                     ETKYAALMEKAEQLVADRQKLQETAANEKDIKRRLKEFKSTLEQNEVLDVFDRHVFES
                     IVEKVIVGGYDEDGKKDPAQLTFVYKTGVKNSVDGSRFKPQRKNARGRHRTDELCSHG
                     SNEVDKTCSDRSNDTL"
     gene            27221..28255
                     /locus_tag="JAM15_11105"
     CDS             27221..28255
                     /locus_tag="JAM15_11105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YHYH domain-containing protein"
                     /protein_id="HAT6798799.1"
                     /translation="MFKKKLIAVAMSITMISVGSFSYAHSGRTDSSGGHRDNKNKSGL
                     GSYHYHCGGYPAHLHNNGGCPYTGGGSSSGTTTSVNNEEKQKRSVGEKGYNQGYEDGY
                     KGNYSSSNYSGDYSDTYESKYSEGYEKGKAKLEEEEKVAKETGYNLGLTGAKSNNTYE
                     KEVLKNAYDTGYSTGYNEYKTKKIEEYKAKGIEDSNKDKEKMTFEENIDSEFIDAYNN
                     AYDEIQEQLKNDYTTQGFESAIKGERFDTSTIGNVKYANWFKEGYDNGKIKLPKAKES
                     VYNQGYNEEDFSIPYEMKSIETKLKGVYDEGLEKREEEKSRNATYGVGAGTAAVVAGV
                     VYKNKKRKKI"
     gene            28342..28545
                     /locus_tag="JAM15_11110"
     CDS             28342..28545
                     /locus_tag="JAM15_11110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4236 domain-containing protein"
                     /protein_id="HAT6798800.1"
                     /translation="MGFNFRKSINLGGGLKLNLGKKSVGISAGVKGARVSVNSKGRKS
                     ATLSIPGTGISYTKTSTKKRKPK"
     gene            28716..29876
                     /locus_tag="JAM15_11115"
     CDS             28716..29876
                     /locus_tag="JAM15_11115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp27"
                     /protein_id="HAT6798801.1"
                     /translation="MKLSKTLLAIGMSVSLLIASCPTSNALSSINSIKGTNKYETAGL
                     IADKQNYDIAILINSENGLSDGLSASGLSGAKNAPILLTKKDTIPSETLKRLEKVKEV
                     YLIGGKNSIGASVQKILSDKKISINRISGTDRIDTSHKVAKEIGRVSTVKKVILTNAF
                     KGEPDAMSVASIAVRDKSPIVLTDGNTTSFATDGLETYAIGGKVSMSDKLINETKATR
                     IGGVDRYDTNKQIINKFYNGSKEFYIASGTDLVYSLVGSTIAQKTPIVLVGNGSNKSI
                     LKNASKITAIGNIDDVIIKQCLNITNNVGDSNTGIVKDTNSNNTNKPSNEPSSNNPGL
                     TDKSTVYVTPNGKSYHLTKNCSTLKRSKTINKVTLKQAKSQGKIDPCNVCVK"
BASE COUNT         9751 a         5443 c         6955 g         7823 t
ORIGIN      
        1 gcaagttcac aaatatgcaa taaatgtggg tataaaaacg aggaagtgaa ggacttaaat
       61 ataagagaat ggatttgtcc tagttgtaat gaaactcacg atagagatat aaatgcaagt
      121 ataaatatat taaaagaagg attaagacta ataacaactc aaaataaata acttatgtaa
      181 gaaccgtagg aactacgggg atagcctgtg gagaattagt aagacatatt ttagtatgca
      241 aaattctgtg aagcaggaac cctgtgactt tagtcatggg aggttcagga tgaataaacc
      301 tgatggatat atatcagcaa ctacagataa atatgaccca acagtattag atttaattga
      361 tttatcatac ttagcttttg aaccatttcc tgttggaagg ttagataaag acacagaggg
      421 attattagtt ttaactaatg atggaaagct ttctcataga gttttatctc ctaagaagca
      481 tgtgcctaag acttattatg caaaaattga tggagtagtt actgaagaag atgtagaagc
      541 ttttttagaa ggtgtagtgc ttgatgacgg atataaaact atgccatcac agttaaatat
      601 attaaaaagt gatgatgaat cagaaataga gcttacaata catgaaggta agtttcacca
      661 agtaaaaaga atgtttgaaa gcgtaggcaa aaaagtagta tacttaaaaa gattgtctat
      721 gggcaattta aaattggatg aaagtttaga gttaggtgag tatagagagt taacagatga
      781 agaagtaaaa ttgattgaag aaagataata aagatactat agtaaattgg aggaatgtct
      841 gtgaagaaaa aagatgttat agaatttgaa gtagataaaa tggaatttgg tggtacatct
      901 ttaagtcaag ttggagatag agttatccat atgaagggtg gaataagtgg tcaaaaggtg
      961 agagctggag ttaaaaaagt tagaagtaag aaagctgaag ttaagatgat agaattatta
     1021 gagaactcac cacttgaaac tgaagaaact tgcaagcact ttagagagtg tggaggatgt
     1081 acactattgt ctgtgccata tgaaaaacaa ttagaaataa aagaaaaaca agttatggat
     1141 ttatttttaa agcaagattt atttggattt cagtttttag ggatagaagg aagtccagaa
     1201 aacaaatatt atagaaataa gatggaatat acttttggag atgaagtaaa aaatggacct
     1261 ttgacattag gtcttcataa aaaaggaaag catatagata tacaaactgt tgaggagtgt
     1321 atgttggttg atgaagactt ctcaaagata ttagtttcta gtgtagagtt tttcaatgaa
     1381 aaaaagcttc cttattatag aacaatgaat cacaaaggat atttgagaca tcttgtagtt
     1441 agaaaaggga ttcatactaa tgagattatg gttaatatag taacttcttc tcaagaagat
     1501 tttgatatga atgagtttaa agatatgctt ttagggattg atttaaaggc tgagttagta
     1561 ggtgtacttc atactattaa tgatggttta gcagatgcag tccaatgtga tgagttaaga
     1621 gtattgtatg gaagagatta tatacaagaa gaaattttag gtcttaagtt taagatttca
     1681 ccattttcgt ttttccaaac caatactaag ggagctgagg ttctttatag tattgctagg
     1741 gattttattg gagattacaa tgataaggtt gtatttgact tgtatagtgg tactgggtct
     1801 attggacagg ttatggctgg tgctgctaag aaagtgtatg gtattgagat agttgaggaa
     1861 gctgttgttg ctgctaatga gaatgctaag ttgaatggac ttactaattg tgagtttatt
     1921 gctggggatg tggctaaggt tgttaaggat ttaaaggaca agcctgattt gattattgtt
     1981 gaccctccta gaccaggcat tcataaggat gctattaggg atatttgtgg atttggtgct
     2041 aaggagattg tttatatttc ttgcaatcct aagtctttgg ttgttgattt ggttgatttt
     2101 aaggggtatg gttatgagat taagatggtt aagtgtatgg atatgttccc aaatacgcca
     2161 catgtagaga ctatagtgtt gatacaaaga aaaactatgt agaaatcctt aattttaggc
     2221 actttttcaa gcatatggtg tttactggcg acggtgaaaa atgcagaaat aaagtcataa
     2281 aagattacat caatgtttct gtagtggttg atatagagtg tggggataca acagaataag
     2341 atttacaaag aggggtactg gataacaaca gtatcccttt cttacgattg ggcgttcagt
     2401 aatgagcgcc ctatttgttt tagaaaaact ttgtatagat ggtcaatcca aaaagtaaga
     2461 tagaaataat gtaaacagga acaaaagcaa atagttgttt ttccttttct tcatacgtgt
     2521 tagacaacgg aataagctta tatattttta aaactgtatg ctgaatccat aataactgaa
     2581 acacaaacaa aacagaccaa ccaattagat taattgtata aagtgagttc tgtatattag
     2641 tgtttatttt ttccaaaaga gaataatcaa ccagtgctaa cccaacaata gcaaaagtat
     2701 ctactactat cttcaaagta aaatatttca tactcattag gttagaaaat atagattgtt
     2761 gtttattcca accacgtaca ataaaaataa tacacagtaa taccaaaatg atagataact
     2821 gtatcattgt gttccgcata gggatataaa aaatggcagt aaaatcagta acagaatgaa
     2881 tggtatttat ttttatgtag ttcacaaaat taattgccat agataaatat atcaaaatta
     2941 tggcaaattg agttattctt ttagatttcc aacgtgcatt ttttattgca acattatcta
     3001 atttgtacat tggagtagat gatactttta tatcgtattt aggattgatt tgttgaatta
     3061 tattattctg aatatattgc tttgtactat tagaagactt ttcccagaat aattcgtaaa
     3121 ttgttaaaac aatagtaatt acatttaaac atattgaaat aatttccagc ataagtttcc
     3181 ctcctaatac gacattatat cacattttcc cttagatgtt cagaagtgaa catctatttt
     3241 tttaccaaaa cgaaaggagc attgattgta tgaaaaagat tatgaaacgc cttttgactg
     3301 gtgtgctaag tctggctgcg gtattcacaa ccttaccggc ttcacaggta caggctgcgg
     3361 agaagcaata ctggacggac gcacaggaaa aggcaggcta tgtagaaaaa gtcatgaatg
     3421 acggcagtat cggttctaca ttccatgagg gcattatgca ggtggagggc gaaaccgcct
     3481 actgcataga catcaacacg gattttgaag cgggctacaa gacacgctcg gatgcaagtt
     3541 cccgtatgag tgccgaccag atcgctgaca ttgcactctc actggaatac gtcaagcaat
     3601 atgcagccag ccacaaagag ctgaattata agcaggtcta tctattggag cagtgcgttg
     3661 tctggcagcg tttgagcgta catttagggt ggaactgcga caatgtacga gctgcctatg
     3721 acgaggtatc caaagcggta caggacgagg tatacgctgg tgcaaaaggt tttgtgaaag
     3781 ccaacaaggg acgctacgac tgcggcggct atatctattc cggcgacgga caggaattag
     3841 ggcagttctg ggcgaagctg gatgtaggaa atgcggcact tcaaaaggtg tcctccaatc
     3901 ccaccattac caacggaaac aacagttatt cccttgttgg tgcgacgtat ggtgtttttg
     3961 ctgataaagg ctgcaaggaa cagcttgcca cccttacgac agataacgac gggaacaccg
     4021 aagctatgga ggtaaaggct ggtaaagtct atatcaagga gttatccgtt ccggcggcag
     4081 gtttccagtt ggacaagacg gtatatccct tgaccgtcaa agctggtgaa acagctacct
     4141 tgaaagtcag cgatacatcc aaagtcacaa ctacactgat tgagcttttc aagatagata
     4201 tggaaacttc aaagtctatc tcacaggggg cagcttcttt ggaggatgca gagttcgtct
     4261 ggaattatta tgacgggtac tacaacaaag acaacctgcc agcaaaaccg acccgtacat
     4321 ggacgacaaa gaccgtggct gaaaaaggca gtgacggagc gacccattat ttcacaaagc
     4381 tgacagatag ttataaggta tccggcgaca gcttctattt acaggatggc gtgccatgcc
     4441 tgccgcttgg aacactgacc gtatcggaaa gcaagagtcc ggcaggttac ttgttggagg
     4501 gtgcgtatat gcaggcgaat ggcagcgagg aacagatcaa aggcacgtat ctgacacaga
     4561 ttaccgaaga tggggagctg gcggtgctta caggcggcaa ccagtattcc gtgtccgaca
     4621 aggttatccg tggtggcgtg aaaatccaga aacgtgacct tgaaacaaag gacacaaagc
     4681 cacagggcgg tgcgagcttg aaagatacgg agttcaccat caccagccta aatgagaacg
     4741 ctgtgctggt ggatggcaag ccctacaaca aaggcgaggt tgtgaaaacc atccttacag
     4801 gcattgacgg tatcgcttct acggctgcgg acacgctgcc ttacggaaca taccgcattg
     4861 atgaaagtaa aagtccagca ggatacttga cgataggtgc ggtttcccgt gaatttacca
     4921 tcacggaaaa cggaaaaatc gtggacttta ctggtgcgga acaatccatc tacaaccaga
     4981 tcaagcgtgg cgacattgag ggtgtgaaaa tcggcgacgg tacacacaag cgtcttgctg
     5041 acgttccatt ccgtattacc agcaagacca caggtgaaag ccacgttgtc gtgactgata
     5101 aaaacgggca gttctccacc gcttctgact gggtatccca taaacagaat actaacaggg
     5161 gcaagaccag cgaggacggt atctggtttg gcacgtctga accagacgac tccaaaagtg
     5221 cgctgcttta cgatacctat gagattgagg aattgcgctg tgacagtaat aagggtttta
     5281 agctcattcc ggcatttgat attgtggtat ccagagataa ggtagtcatt gacttgggaa
     5341 cgctcacgga tgattacgag aaaaaaatct ccatccatac cacggctgcg gataaagcca
     5401 cagggaagaa agtaatcgtt gctggtaaag aggtcacgat tgtggatacg gtcacgctgg
     5461 acggtttgaa aaaaggcaca aagcaccagc ttaaaggctg gcagatggta aaggatgaaa
     5521 acaccgagct tcttgttgat ggtgagcgtg tagaaagtga atacacattt actgccgacg
     5581 gtgaggaaat gaaagtcaaa gtggaatata cgttccatgc ttctgccctt ggaggtaaag
     5641 acttggttac ttttgaagaa ctgtacgact tatccgacaa gaacgagcct gtcaaagtgg
     5701 ctgaacacaa ggacattgag gacgacgggc agacagtatc catcaaagag cgtgtaatta
     5761 aaatccatac cactgctgcg gacaaagcca cgggcgagaa agtaatcgtt gctggcaaag
     5821 aggtcacaat cttagatacg gtcacgctgg acggtctgga agtgggtaca aaataccagc
     5881 tcaaaggatg gcagatggta aaggatgaaa atgtcgagct tctcattgac gggaaacgtg
     5941 tagagaatga ctacacattc accgctgctg acaccaaaat ggaggtggaa atttccttta
     6001 cgttcgacgc ttcaaagttg ggcggcaggc aacttgtgac ctttgaggaa ctctaactct
     6061 acgacatcac caatcccgac gagcctgtaa aagtcacaga acataaggac atcacagaca
     6121 aagggcagac ggtcacaatc aaggaagtgc cggaaacgcc tgagcccgaa gaaccaaaga
     6181 aaccggaaac accagacact ccgagccata aggtgacgga ctcacccaaa acgggtgaca
     6241 acaccaatgt ggctgccttt gctgtcctgc ttggactctc tgcggctggt cttgcctttg
     6301 cagcctataa gaaacgctgt tccataaagc atgacggtga taaataaagt gtgaggtgac
     6361 tgcctatgaa gctgcataca cgctcaccgc ctgccgggat ggttcaaact gccggataaa
     6421 acctttacac tgattctttt ctgtcaatcg tcttttggat tgatggaaaa aaacagtcca
     6481 ctagggggta tgggggattg tagctccccc atgctcttcc cttaagctac gcacatagaa
     6541 agaaaagagg taaacacata tggaattaaa acacgtaatc cctaacatgg aaaagacatt
     6601 cggaaacttg gaatatgctg gagagggcaa gaccgagcag cgccgggtaa acgggcgcat
     6661 gacggtcatt tcccgaagtt tcaatttgta ctctgacgta cagagagccg acgacattat
     6721 tgttatcctg cctgcttctg ccggagagaa aaattttgag gtagaggaaa aggtaaaact
     6781 tatcaacccg aaaatcacgg ctgacggtta caaaatcggc acccgtggat ttaccaacta
     6841 tatcctgtcc gctgacgaca tggtgaaagc ataaggaggt catgagatta tgagattagc
     6901 aaacggaatt atcattgaca aggaaaagac attcggggtg ttgaaatttt cagcattgcg
     6961 ccgagaggta cacatccaga atgaagatgg tacggtatcc gaggaaatca aggagcgcac
     7021 ctatgatttg aagtccagag gacaggggcg catgatacag gtgagtatcc cggcttctgt
     7081 gccgttgaaa gaatttgact acaatgccga ggtggagatc atcaacccgg tggcagatac
     7141 ggtggcgacc gccacatttc aaggggcaga cgtggactgg tacatcaaag ccgacgacat
     7201 tgtgttgaag aataaaggcg gtcagccagt agccaatcca cagaaccata accagcaacc
     7261 acagggaaag aaataggtga ttataattga ttgtaaatga tattaagtag atgtataata
     7321 ttcttgcaaa ggataaattg aaagggagga attagctgtg aggataaatc ataatgacgc
     7381 aattagtttg gaacatattg ttagaggtgt ttttgtatgt gatcgtgctg gaatgggtgg
     7441 atatattgat gctgaccatt ttgaatcagc gccatttgat gcagcactga ttgcactggc
     7501 tccattatgg caaaaagcag attttcatga aatagaagat tttctattta agtgggaaca
     7561 aacactgcgt aataccgata acatgagcgt cgatattcag tcatatattc aagaattgga
     7621 tagtcttgtc actctcctta tgcaacgata gctccagttt atctataact tcataattaa
     7681 tgccataagc agttagtctt tatgattaac tgcttttttc atacccagaa agggggattt
     7741 atgcgatttt acaaccatta taaaggcaac cgtatccgag ccagtgacag gtcgctggtg
     7801 gtgcggtcaa tgagcggtca gctggcgtgc ctgttccttt tggtcgtgct gcttttgaat
     7861 atcaatacgc tgctgcatac agactggaac acgttatccc tatttcagaa tggcagcata
     7921 aagctcacgg tcacacccta catgatagta tctctcatag tggcggtgct ggtgtgcggc
     7981 ttggctgcgt ttctgtatgc ccgttaccag ccggacagga taaagcagct ctgtcaccgc
     8041 caaaagctgt cacggatgat actggaaaat ggctggtatg agtccgagca gtcacaggat
     8101 ggcggctttt tcaaagacct gccagccagc aggtcaaagg agaagattac ccactttccc
     8161 aaagtgtact accgcttaga caacggactc attcacatac tggcagaaat cacgttgggg
     8221 aagtatcaag accagctctt acacttggaa aagaagctgg aaacaggctt gtactgtgag
     8281 ctggtttcca aagaactgaa agacagtttt gtagagtatg tgctgctcta tgacaccata
     8341 gccaaccgta tcaccataga cgaggtacag gcgtcaggtg gcagcctgcg gctcatgaaa
     8401 aatgtgtatt gggagtatga caaactcccc catatgctga ttgctggcgg tacaggcggc
     8461 ggtaagacct actttattct taccgtcata gaagcacttc tgtgtaccaa cgctgaattg
     8521 tatgtgcttg acccaaagaa cgccgacctt gccgacctgt ccgctgtcat gcccgaagtc
     8581 tactaccaaa aggagaaaat tacagactgt atcgaccgct tttatgacgg catgatggaa
     8641 cgaagcgaag ccatgaagct catggagggg tacaagacag gggaaaacta tgcctactta
     8701 ggtctgccac cacactttct gatatttgac gagtatgtgg catttatgga aatgctgacg
     8761 acaaaggaaa atgctgcggt cttaaacaag ctgaaacaga ttgtcatgct tggacggcag
     8821 gcaggctatt ttctcattct cgcctgccaa cgaccagacg caaaatacct tggcgacggc
     8881 atccgtgacc agttcaattt ccgggtggca cttggcagga tgtcagagct tggatattct
     8941 atgatgttcg gtgaggtgga caaagacttt ttcttaaaac agatcaaagg gcgtggctat
     9001 gtggatacgg gtacaagtgt catatcagag ttttacactc cccttgtacc caaagggcat
     9061 gacttcctaa gagaaatagg acggctcatg caaaacaggc aggacggaca ggcggcgtgc
     9121 gaagcgaaag ccgctggttc ggactagccg tgttggggcg gcgtgccgcc acaaccattc
     9181 gcccccccgg tatctaacag gggggcacaa atacaatagg aaacagtcaa agaagttggg
     9241 aaaatccttg taaatggagg actttttcta ctttcagagg gtggcaactg gaacgcttct
     9301 agttgacact ttttcaagat tggagggatt tttactgaat gatacagact ggaacacaga
     9361 tttaaaagaa aagcggctgt catacggcgt ttcacaaaac aagctggcgg tagcggctgg
     9421 cattacaagg cagtaccttg tcaagataga gtccggcagt gccgctccca gcgaggaaat
     9481 caaagaaaac ctgctgcaag ctctggaacg gtacaacccg gaaacgccgc ttaccatgct
     9541 gtttgactat gtgcggatac ggtttcctac cacagacgtg cggtttgtgg tcgaaaccat
     9601 tcttaaattg aagctggact ttatgataca tgaggacttc ggcttctact cttatccaga
     9661 gcattactac atgggggata tattcgtctt ggtatccccc gaacaggaaa agggggtgct
     9721 gctggaactg aaaggaaaag gctgccgcca gtttgaaaat ttcctgctgg cacagcatag
     9781 gagctggtac gacttcttca cggacgctct ctgtgagggc ggcgtgttca agcggataga
     9841 ccttgccatc aacgacaggg tggggatact ggacattcca gagctgaccg ctaaatgccg
     9901 gaatgaggaa tgtatttccg tattccgaag tttcaagtcc taccgctccg gcgagctggt
     9961 gcagagtcat gaggaaaata agtccggcat ggggcatacg ctctatatcg gttctctgaa
    10021 atcagaagtc tacttctgtg tgtacgaaaa agatttcgag cagttcgtaa aatacgacat
    10081 ccccattgag gaaacacccg ttaagaaccg ttttgaaatc cgtttgaaga acgaacgagc
    10141 ctactatgcg gtgcgtgatc tgctgaccta ctatgacgct gaacgcactg ctttttccat
    10201 catcaaccgc tatgtgcggt ttgcagataa ggacgaaaca aaacgtcgga gcgaatggca
    10261 gacaaatcag cgttgggcgt ggtttctcgg tgaggggcgt gggcggctga aactgacgac
    10321 cgaaccggaa ccgtataatt tccaacgcac cttaaactgg ctggcaaggc aggtcgcccc
    10381 taccttacag gtggcggaaa agctggatca gcagaacaac acgacaatca ttaaggacat
    10441 ggtgaaacat gcgaagctct ctgaccgatt agaaaaggtc ttgcggcagc tctccgtcac
    10501 cgtggaggaa atgaccgtca aagacaagga ggaataagaa atgtggcata tattgtttga
    10561 cctgctgttg gtatcggcag gcatgggaac gggtgtggtg cttatgtgta tcctgcaagc
    10621 cggcaaagaa gcggacacct gcttagaaga aatggaaagg agcaatgaaa aatgaatttt
    10681 ggacagaatc tatacaactg gtttttgagt aacgcacaga gccttgtgct tatggcaatc
    10741 gtggtgattg gcatttactt aggttttaag agagaattta gtaagctgat aggctttctg
    10801 gtgattgcct taattgctgt cggtctggta tttaacgctg gcggcgtgaa agacgtgtta
    10861 ctgaacttat ttaacaagat tatcggagct taaacttatt gttccatccc acatgaaatg
    10921 gtataatttg atataagtta ccgaattatg gagggatgat tatgaagaat attctagttg
    10981 gcaatggtat caatattcaa tatgacaatg aaaattatac ctgtaaaaat attgtattaa
    11041 gggttttgac tgagttagat gaggaggatt acccttgtga gtatatagtt gacaatccta
    11101 tgctaataaa gagttatatg ggtaaattat ttttagcggc aagagaagca ttagacggag
    11161 gacttgataa atatccgaat tgcacagcag aacgtaaggg cttaaatgat tttaaagacc
    11221 gttataaaag caaaaaaaaa tcattgcgta ttgctgatat agggtttgaa gattattatt
    11281 taattcatga tttactttgt cataaaacac atactcagaa tccagagcaa tatacaatta
    11341 gagaatccct taaaatggct tattttcact ctatatacaa tcgtgggaaa ttaaacttgc
    11401 tacataaaga atatagtctt ggcttggttg attatctaaa atcttttgac aatatattca
    11461 cgactaatta tgatagcaat ttagaatcag cgacaggaaa aaaaatatac catattcacg
    11521 gacaatttga taaattaagc gagacatata atccgacttc attcagaaat cacttaaatg
    11581 ataacccact agaagggata cctaaccaac cagaatataa acatttacac tctacagctt
    11641 tgtcaactta ttgtggtgat tacaaaagat accagattaa acagaatata ttggctaatg
    11701 aagccctaga aaaaatggca aatggatacc aaacaatgac ttccatcaaa aaagatgttg
    11761 acacatggga aacagaaaag aaccaattag ttgttaattt agggcaggcg attaaattaa
    11821 aggtagccaa tcccaatttg cgctttcaag aggattacta tgttaaggaa tttcaagcaa
    11881 taacaggtga actaaccata ttaggactat ccccatataa tgattatcat atatttgaaa
    11941 tgattgaaag tgctaaatta ttaaagtgca aattttatta ttataacgaa tcagaatgtg
    12001 aaagaataaa aactctttta cctaatttat atagggaaag aaaattggaa tttcttaatg
    12061 tacagatttt ttgggagggt ttataatgtc acaggtaaag tacactaaaa tcacgagaaa
    12121 aaagttgttg cagtctttag ccgcttataa tcttttatct catagccaac aagattggag
    12181 agtaattata aaagaattta attctctttc atttagccag cgaaatcaaa ttattcaaga
    12241 agaacagtta agagaacaat tattaaaaga taaaatgact actactgatg aagatatgta
    12301 tttaacttgt acaatggtaa atttgaacat tgtggcatct aaatttgata tagatccaac
    12361 aactgtatgt atgtgtatcg caccactagg caagataaat gaaaacatat tagtagttta
    12421 atactaaagc agcagataac aaaatgtttg ctgctttttt cttgcttatt tatcagtatc
    12481 ctgttttatt gggaacacta acaaaaattg aaaggatgtg atttatcact atgtatgaaa
    12541 tgagattata catcctcaac accacaaagc cttaccgtga cgacgaggat gagtatgcag
    12601 gcgcatggtt tccttgccct gtaacctttg aggaaatcaa ggaaaagtta ggcgtggaaa
    12661 aagaggaaga ttttgaaatt gaggactacg agctgccttt ttccctaagt cctgatatgc
    12721 cgctttggga aatcaacgct atgtgccgca tggtgcagga aatcgagggt acacccattg
    12781 gcaatgaatt aagcgagata caggcaaagt ggtttcacaa catcagtgac tttttcgacc
    12841 acaaggacga gatacgccac tatgatgtgc cggactccgc ttctttggca gaataccttg
    12901 tcatggagga acaccgcttc ggggagctgc cgccggaact tgcaaagcac atagacttta
    12961 tttcctacgg gcatgaactg gaacaaagcg acgaatacct ctttacgacc agcggcgtgt
    13021 tccgctatcg gtaaggcggt ggctgccttt ggaggaaatg cgtgtctata ttgccaacct
    13081 tggcaagtac aacgaggggg agcttatagg cgactggttc acgccgcctg tggactacga
    13141 cgagatggca gaacgaatcg gcttgaatga ccgatacgag gaatacgcca tccatgacta
    13201 tgagctgccc tttgaaatcg acgagtacac acccattgag gaagtcaacc gcctgtgcga
    13261 gatggtggaa gaactggact atccgctgga tgaggtgatt gacgacctgc tctgccattt
    13321 ttgcagcgtg gaggaacttt acgaccacaa ggacgacatc atccagtacc cttgcgacag
    13381 catggtggac gttgcctacc acttaattga cgagtgcggc gttttgggcg agatacccga
    13441 ccgattgaga aactacatag actatgaagc ctttgcccgt gatattgact tggaggggtg
    13501 cttcatagaa accagatacg gagtctttga gtgtccgtat taacaagctg gcagacctgc
    13561 acaaacgtgt gattctggca gcttatttta ttaacagcag tctgtgaaat gcaggctgct
    13621 gtttccattt tagaagaaag gaatggtaca aaacattgaa gaaaataaga agctatacca
    13681 gcatttggag cgtggaaaag gtcatttacg ctatcaacga ctttcagctt ccgttcccca
    13741 tcacattcac acagatggca tggttcgtgg tatccctgtt tgcggtgatt gtgtttgcag
    13801 agctgccgcc cttaaacatg attgacggtg cgttcctcaa atactttggt atccccgtgg
    13861 cggtgacgtg gttcatgagc cagaaaacct ttgacgggaa gaaaccctac ggtttcctaa
    13921 agtccagtat cggctacctg ctgcgcccga aagtgaccta tgcaggaaaa gcggtgaagc
    13981 tgaaaacaga actattgaat acagccataa cggcagttag gagtgatgtg tatgttcccc
    14041 attaaatata tcgaaaacaa tctggtgttc aaccatgacg gggagtgctt tgcctactat
    14101 gagctgatac cttacaatta ttcgttcctg tcaccggagg aaaagtacat ggtgcatgac
    14161 aacttcaggc agcttatcgc acagaaccgt gacgggaaga tacacgcctt gcagatcagt
    14221 accgagtcca gtatccggca gacacaggaa cgctccaaaa aggaggtcac aggccggctc
    14281 cgtgaggtgg cttgtgcaaa gatagacgaa cagaccgaag cgttggttga aatgattggg
    14341 gaaaatcaga ttgactaccg cttttttctt ggctttaagc tgctggtgaa cgaggaagaa
    14401 atcagcttga agcacgccgg aaagtccgct gccatgacct ttgccgactt tctctacgag
    14461 gtcaaccatc agctcatggg ggattttgta tccatgagta atgatgaaat cgcccgtttc
    14521 caaaagatgg agaagctttt ggagagcaaa atctcccgcc gctttaaaat ccggcgcttg
    14581 gaaaagcacg attttggcta cctcattgag catatctacg ggaaaacagg cgttgcctat
    14641 gaggactatg cctacgactt cccggtaaag aagctgaaaa aagaaacgct ggtaaagcgg
    14701 tacgacctta tccgtccgac acgctgccag atcacagaga accagcggta cttaaagatg
    14761 gacagtgagg aacagacgac ttatgccgcc tacttcacca tcaacaatat cgtcggggag
    14821 ctggactttc catcttcgga aatcttctac tatcagcagc aacagttcac gttccccgtg
    14881 tccacgtcta tgaatgtgga aatcgtcacc aacaaaaaag cattgacgac ggtaaggaac
    14941 aagaagaaag agctgaaaga cttggacaac cacgcttggg agtccaacaa cgaaaccagc
    15001 aacaacgtgg tggacgctct ggactctgta aatgagctgg aaaccacctt agaccagtcc
    15061 aaagagtcca tgtataagct gtcctacgtg gtgcgtgtgg cggcagatag cttagacgaa
    15121 ttgaaacgcc gctgtgatga agtcaaggac ttttacgacg acctcaatgt gaagctggtg
    15181 cgcccgttcg gggatatgct tggtctgcat ggggaatttc ttccagccag caagcgttac
    15241 atcaatgact atatccagta cgtgacaagc gattttctgg caggtcttgg atttggtgca
    15301 acacagcagt taggggaaag cgacggtatc tatatcggct ataaccttga cacgggcaga
    15361 aatgtgtact taaaaccgag ccttgcggca cagggagtca aaggctctgt gacaaacgcc
    15421 cttgctgcgg cgttccttgg ctcactaggg ggcggtaagt ccttttgcaa caacctcatt
    15481 gtctactatg cggtgctgtt cggcggcagt gcggtcattg tagacccaaa atcagagcgt
    15541 gggaactgga aagaaacgct gccggagatt gcacaggaaa tcaatatcgt gaaccttacc
    15601 agtgaagcga aaaacaaagg actgcttgac ccttacgtga ttatgaagaa cttaaaagac
    15661 gctgaaagcc ttgcaatcga catcctgacc tttttaacag ggatcagcag ccgtgacggt
    15721 gagaagtttc ccgtacttag aaaggcaatc cgctctgtca cacatggcaa aaggcgaggt
    15781 cttttgtgcg tcattgacga gctgcggaaa gagggcacac ctgttgccag caacatagcg
    15841 gagcatatcg aaagcctggt ggactatgac ttctcccacc tgctcttttc cgacggtgcg
    15901 gtggaacagt ccatcagctt ggataagcag ctcaacatca tacaggtggc tgatttggtg
    15961 ctgccagacc gtgacacgaa gtttgaagaa tacaccacaa tggagctgct ctccgtggct
    16021 atgcttattg taatcagcac ctttgctctc gactatatcc actctgaccg gagcattttc
    16081 aagatggtgg atttagatga agcgtggaca ttcttacagg tggcacaggg caaggctctg
    16141 tccaacaaac tgatacgtgc cggacgttcc atgaacgccg ccgtttattt cgtgacacag
    16201 aactccggcg acgtggacga cgagaaaatg aagaacaata tcggtttaaa atttgcgttc
    16261 cgctccacgg acataggcga gattaagaac acccttgaat ttttcggggt ggacaaggac
    16321 gacgagaaca accagaagcg gctacgggat ttggagaacg ggcaatgcct gtttcaagat
    16381 ctctacggcc gggtgggtgt gatccagata catcctgtct ttgccgacct gttccatgcc
    16441 tttgacacca gaccgccaat ccagacagaa gaaacgaggt gaagtccatg agaaagaaaa
    16501 agatagtcca ctatcttggg attgctctgc tggtggcatt tgccacactt gtgttcttgt
    16561 ctgttacggg tacggtggct catgccgccg gattggtgga cgacacggtg gacgctgcca
    16621 accagtattc taagtatccg ctggaaaact accagcttga cttttacgtg gacagctcat
    16681 gggattggct gccgtggaac tggctggacg gtatcggcaa gagtatccag tacggcttgt
    16741 acgccataac caactttgtc tggacggtca gcatgtatat ctccaacgcc acagggtacg
    16801 tggtgcagga agcctacaag ctggacttta tctccgatac cgcaaatgca atcggaacaa
    16861 acatccagac ccttgccggg gtaaatgcag gcggcttttc cacacagggg ttttacgtgg
    16921 gtttcctgct tatccttgtg ttgctggtgg gtatttacgt ggcgtataca gggcttatca
    16981 agagggaaac cacaaaggct gtccatgcgg tcgtcaactt ccttgtggtg ttcgtcctgt
    17041 cagcgtcctt tattgcctac gctcccaatt acataacaaa aatcaatgac ttttcttcgg
    17101 acatcagcag tgcggcactg tcactgggta cgaaaattac cctccccaac tccgacagtc
    17161 aagggaaaga cagtgtggac ttgatacggg atagcctgtt ctccatacag gtgcagcagc
    17221 cgtggctgtt attacagtac ggcaactccg atatggagga cttgggtgca gaccgtgtgg
    17281 aaagcctgct ctccgccagt ccagacaccg acaccagaga ggatacggtg attgcggaaa
    17341 ttgaggacaa ggacaacgcc aatatgagcg tcacaaagac tatgagccgc ttgggaacgg
    17401 tggtctttct gttcctgttc aatatcggca tttccgtttt tgtattcctg cttacgggca
    17461 tgatgatatt ttcacaagtg ctgttcatca tttacgctat gttcctgccc gtgggcttta
    17521 tcctgtccat gataccctct tacgagggaa tggcaaagaa agccatcaca aagctgttca
    17581 acaccatcat gatgagggca ggcattaccc tcattatcac cgccgccttt agtgtgagta
    17641 ccatgttcta ctctatctcg gcaggctatc cgttctttat ggttgccttt ttgcagatcg
    17701 tcacttttgc aggcatttac tttaaattag gcgatttgat gggaatgttc agtttgcagt
    17761 ccggcgacgc tcagcaggtc ggcaggcgta tcttccggcg accttatatg ctcttaaacc
    17821 gtggggcaag gcgcatggag cgtcgtgtcg gcaggacgtt agccgctggt atggctggcg
    17881 gtgcggcagg tgctgcggtg gcttctggca gccgtaaaac tgatacaaga aaatcagcgg
    17941 acagacagaa ccataccaca ggcagccgcc ccagccacga tacagggcaa tccggcgata
    18001 ccgctacttt tggcaagcgt gctggctcta aggtgggtgc ggtgctggat acaaagcaga
    18061 gagtcaagga caaggcacag tctgtcaagg aacaagtaaa ggatatgccg acacaggctg
    18121 gctacgccgt ccattccgtg aaagaacggg caaaggaaaa cgtgtccgac ttcaagcgtg
    18181 gcatggtgga agaaaaaacc acccggcagc aaggacgggc ggcaaaacag gacagccaca
    18241 ggcagaccat agcggaaaaa cgcatggcaa tggaaaaggc aaagccgacc ggatcagcgg
    18301 cgaaaggtac tgcccctgtc catgagcgac cagccacaat gcctgtatcc ggtgcaacga
    18361 caccacaggc gaccgctgcg aaaggtgcag ctcctaagac agagccgacc agtaaggaac
    18421 gtccggcggc agtacccaga gaaagctatg agaagccaac aaccacgaaa ggcagagagc
    18481 cagcggcaaa gccacaggaa cagcgcacac aagtggtacg ggagtctggg gcacgttccc
    18541 agacggtaaa agaaccagca aaaccacagg tgataaaaga gcctgttcct gccggaacta
    18601 agaccattcg gcaaaccagt acacagaaaa cgaaccggaa catccaacgt aataccgtaa
    18661 agaaatcctc cacccacaca acgaagaaag gacggaaaaa atgaagctgc ggcatttagc
    18721 actgcttggt gggattttca cagtgattat cagcctgcta ctgtttttgt ttatcgtcac
    18781 atccgacgac gaggaaagcg gtggcagctc cggctttgac tattcgggga tgaacctgtc
    18841 agcggaggtc ttgaaacatc agccgaccgt ggagaagtat gcgaagcaat acggcatttc
    18901 agactatgtg aattacctgc ttgccatcat gcaggtggaa tccggcggca cagcggtaga
    18961 cgttatgcag tccagcgagt ctttaggtct gccgcccaac tcgttaggaa cagagcagtc
    19021 cattgaacag ggatgtaagt attttgcttc tctgcttgct tcagcaaaag cgaaaggctg
    19081 tgatataaac accgtcgtcc agagctacaa ctatggcggc ggttttattg attatgtggc
    19141 aagccacgga aaaaagtaca cctttgaact ggcggtcagc ttcgcaaggg agaaatccgg
    19201 cggtgtcaaa gtaacttata aaaatgaaat ctccatcaag gaaaatggcg gctggcggta
    19261 caagtacgga aatatgtttt acgtccggct ggtggcgcaa tatctggcag tgcctaattt
    19321 cagcaacgcc acggtacaga caatcttcaa tgaagctctc aaatatcaag gctggacgta
    19381 tgtattcggg ggcgataacc cgaacaccag ctttgattgc agcggtctgg tgcagtggtg
    19441 ctatggaaag gctggtatca gcctgccgag ggtggcgcaa gaccagtacg atgcaacaca
    19501 gcatattcca ttgtcacagg cgaaagcggg tgatttggta ttcttccaca gtacctacaa
    19561 tgccggcacc tatgtaaccc acgtcggcat atatgcagga aataaccgta tgtatcacgc
    19621 cggaaacccg attggctatg cagaccttaa cacttcgtac tggcagcagc acatcattgg
    19681 tgccggacgt gtaaaatcca actaggacag aaaggaaatg gtaactatga gattaaagaa
    19741 gaaagagaaa gaagcaaaac ctaacaagac gaaaaaagta cgtgttctaa aagcaggcac
    19801 gcataagaaa tccgtgattg ccctgtggct ggtgctgatt gccagtgtca gcttcggggt
    19861 atataagaac ttcaccgcca ttgatatgca caccgtccac gagaaagagg tcatagagca
    19921 gcgtatcgtg gataccaaca aaatagaaaa cttcgtcaag gactttgcaa aagcctacta
    19981 ttcatggggg aataacaaag aagccattga agcaaggaca aaagccatca gtcagtttct
    20041 aacaaagagc ttgcaggatt tgaatgtgga cacggtgaga agtgacattc ccaccagctc
    20101 tgcggtgaat gaggtaaaaa tctggaactt ggagcagact ggcacagaca agtataccgt
    20161 cctctattcg gtcgatcaga ccatcacaga gggcgaccag accagccgta atactgctgc
    20221 ttatactgtg gtggttcatg tggatggcga tggaaacatg gttatcacaa agaacccgac
    20281 catcagccgg ataccagcaa aatccagcta cgagccaaag gcagcggaaa gtgatggaac
    20341 ggtggacgtt gccaccacag aggaagtgac cgagttcttg gaaacattct tcaagctgta
    20401 tccggcggct acggacaagg agctttccta ctatgtggct ggcaatgcgc tgaaacctgt
    20461 aaacactgat tatctgtact ccgaactaat caatccgctg tttacaatgg atggggataa
    20521 ggtcaaggtg tccgtatcag tgaagtatct cgaccagagg acaaaggcgg cacagatttc
    20581 acagtttgac ttggtgctgg ctgaaacaga tgggaattgg aagattgtaa aatgaatact
    20641 atcttatttc taatttcata ttgactttaa taaaatttat ggtatactta attttattaa
    20701 agacatatga aaggaggatt tgaattggag attgataaaa ttccccaatg gattcttgcc
    20761 ttagagcaag aggacgccac ttttctaaag aactttgtgc taaaatctgg ttctttaaaa
    20821 gaagtagcaa agctgtatga ggtttcttat cctactgttc gcttacgatt agataagctc
    20881 attcagaaaa tacagataag cgatcaacaa gaagaggaac cattttccac ttttattaaa
    20941 ggacttgcag ttgactcacg aattgatata gagactgcaa aaattattat tgaaaaatat
    21001 aaaaaagaaa aggagaaatg attatgttga ctaatattat gtcaatattg ggtactattg
    21061 tagccacatt aattattaca ggcactcaaa aatatttaag tacgaggaga aagtggcaat
    21121 taggtagtat tgttcctatt gtttctattc ttgttatggc gacagtgctt tatataacaa
    21181 agattaatct ttcaattaaa gtgtttctgc catgcattat tattcttgtc ttagaactgt
    21241 ttatttggtt tgatgggcga aaagaataca agaaagagga atttagaaaa atgaaagcaa
    21301 aagatattgt ataattaagg ttataaaaag gagtgataat tatgtttgat ttagctgttg
    21361 gttttgccat tgctggtatt cttatggtag ttgaatattt tatttgtacc agattaaaca
    21421 atgcactgtg gggtggaatt atccctatac ttatattgat aggcacagtt tggatttttg
    21481 tatcgggcaa agtgccgttg gaaataaaaa cgatatttcc gtttattatc tgcaactcaa
    21541 ttttccttgg ggaatgggac aatggaagaa agaaatatac tgaacgaaaa aaggctgaga
    21601 tggacaaaat gaaagcaaaa gatatttaat attgggaggt atatatggga gaagaacact
    21661 gggtattttg tcctgtttgc cacaataaaa ccagagtgaa aattcgtgga aatactatac
    21721 ttgaaaattt cccactgttt tgcccaaagt gtaagcagga aactttgata gacgtaaaaa
    21781 acttaaatat atcaattaaa gagccagaca ctaagatgca gagccggtaa tttagaggat
    21841 tttatacctc atagattatc ggctcatttt tattgcctgc caccatatcc cgtatgattg
    21901 gcaggcaaat aaaaatggag gagctattct tcctccagtt cctttgattt gatgatacca
    21961 gcagcgacac tttccatgat aaccatatct ttgtcgtcga aagtatcaag ctgctgctcc
    22021 aactgtctgc ggcgagtgct tttcacttta tcgctggacg gcaggaaaat ttcatcaacg
    22081 gatacattga gtaaagttac aaggtcgtaa aatatctgta aactagggtg ctacccctta
    22141 ttctcaatgt ttgtcagata gcgtgggtca atttcaattt ttgcccccac ctgttcacgg
    22201 gtcagacctt gtttcagcct tgccgctttg atggcaagtc caaaggctct gaaatcgtat
    22261 ttatcttctg ctttacgcat agttaatcac ctcactacat tttatagttc ctaaaggaat
    22321 agtaacaggt atagaaaaac gtgatataag gtttattggt tcctattgat gtgatataat
    22381 ttaaataaat atgcatattc ttcttgacct tataccgcac tgcaaaggtt agaatagcag
    22441 tagaaagagg tgagcagtat gtatcgaata ggtgaatttt caaaaatcac aggtctaaca
    22501 acacagactt tacgttatta tgacagtgaa aaaatcttat ctccttcata tcgaaatgag
    22561 gaaaatggtt atcgctatta tagtgcagac gacattgaaa cagctcaata catttcattg
    22621 ttaagaaaat tcaatttctc gattatggaa atcaaagatg ttctatccaa tatgaggaca
    22681 caagaggatt tcaacgattt tattaatgag aaaattgtat taacggaaaa tctaattatt
    22741 cagcataaat ctgtaattga tgaaatgaaa tcttatttat ctctgacacc tcttgaaaaa
    22801 aaggaggtcg agaacatgaa atacgaagtc aacattacag aattaagctc tcaattagta
    22861 gcaagtatcc gatttaaagg aaaatactgt gaaatctgtg aatattttac aaaagtcttt
    22921 gaatgtgcag atgaaaaagt gtgtggtatc ccatttactt gctattacaa cttagaattt
    22981 gcagaaacag cagatataga agtttgcgtt cctgtttctt catctgtatt tggaaatggt
    23041 atacagacaa agacgattga gggtgtacgt acgattggcg taaaacatat tggtgcttat
    23101 gaaattctag gtatggcata caaatcctta tttgattatg caaatgaaaa caacttagat
    23161 tacattgcgc caattataga attttatgat aagagtatgg gatacacctt aaagggaaac
    23221 ccagataagt acgaaacaag gatttatttg ccaatcaaaa aataaaaatt actcctatgc
    23281 ggtaaataaa aaaaccgcta ctgagtaata tacttttatc tgcacgaaaa tagcataatt
    23341 aaatggcggt tttgagaaat cagagccgcc gttttatttt gcctagcggt ggatgaacta
    23401 ctgtaaggct ttgttttagt ggctctaagg ggaagcctat gaaacactta tgtattcgac
    23461 aacttgcgac caccggtagc ttgtcaaaaa aatccgttca aagtttacgg attataacgc
    23521 tcctgcatat ggtttttcac gtcatataac aggaacaatc tataaagtac aagaacagta
    23581 cgtcagtatt gcccttgtgc ttttttgctg cacaaaactt tttcaaaaag tttttgcggt
    23641 tgggtatcaa atcccacctc ttgcggcgag tgttagtgcg aaaagaggta gaagcctttt
    23701 cgctttagca actttagctg gaaaggaggt gagattatga agccatcttc tttcgagaac
    23761 gctatcagac ttcaatttga ttgtctggct cgtaaggtcg taggaacaac cgtaaaggac
    23821 tataaccgtg agcttggcag acgtgcaaag cgtgaaactc cattctgtga gctgccggaa
    23881 atggaattaa accatatcgg cacttacgac gaatactcgg ttgaatttac agcctttgac
    23941 gtattcggca atgaagtccg tatctatgat gaacagctat gtgaagcaat caaagaatta
    24001 aatgaaaggc gacgtaacat tctgcttatg tcctactttc ttgagatgac cgacgctgaa
    24061 attgcagagg tcatggaaat ggaacgattt tccgtttgta gaaacaggct gcacacatta
    24121 aagctaatca gagatatgta cgaggaggaa taaaacatga cgaagtctac aaagaagtgt
    24181 ccattatttt ccacgatcag ctcggctgct gacggtgacg aggtagcaat cggaaagatt
    24241 ttaaaccact atgacgctta catatcaaaa gccagtttac gcccgttcta tgacgaacac
    24301 ggaaatatgt atatcgtggt cgatatggaa ctgaaaggca gaataagagc tgcgctgatt
    24361 gaagcaattt tgggatttga aatcaaagtg aaataagttt aacagagagt gtctaccacc
    24421 tcatttccgc tctttactgt tctttgaaaa ctgaataaag taatcagata cgtttgatat
    24481 gcggcgagcc tgcggactgg aacgccacga ccactgaaag gagggaaaca gcgagcgacc
    24541 acgccagtga tccgcaagca actgttggaa aggttgctgc catgacccgt atatcagaat
    24601 aatgatacac ccgtaagaca cggttcaccc atcagaatgg gaatggtgaa agtctagtgg
    24661 agctgccaaa gccgtctgat tacttctaaa tcaaaaaacg caaggagggg tttcatgaat
    24721 aatttgattc gttatagtat gcaaattgcc atgctaaaac aactgcttgc ccgtaaattg
    24781 atttctgaaa gagagtatac ccttgtaaaa caaagattga tgaaagatta caaagtgctt
    24841 tctgacataa ctgcttgaat tgtgtttcta aaattgatat aataacacta taaaaggaac
    24901 acaaaaacag ggagggttat tatgcaggaa gttgaagtta taaaagcaag aaatgtttta
    24961 tcaaagcaag cccgtggaaa agccattgag cgtttacgtg tagctgcata ttgccgtgtc
    25021 agcacagaca gtgaagatca gttgaacagc tataagtcac aagtccagta ttatacggat
    25081 atgattaaga agaataagga atgggtatta gttgatattt atgctgatga agcgattacg
    25141 ggtacacagg tgataaagcg agaagatttt cagcgcatga taaatgactg tatgaatggc
    25201 gacattgata tggtgattac aaaatcaatt tcaagatttg ccagaaacac gttagataca
    25261 ttgaaatatg ttcgtatgtt gaaagaaaga aatatcgctg tctattttga ggatgaaaaa
    25321 atcaatactc ttacaatgga cggagaattg ttgcttgttg ttcttagctc tgtcgcacag
    25381 caggaagttg agaacatttc agctaatgtg aaaaaaggct taaaaatgaa aatgaagcgt
    25441 ggcgagctgg taggttttca aggctgcctt ggctatgatt atcacccgga ggacaagaca
    25501 attactgtca ataaagaaga agcagagatt gtcagataca ttttcaaccg ttatgttgag
    25561 ggagctggcg gttctgttat cggacaggag cttgaaaatc taggctacaa gacaaaatac
    25621 ggtagttcta cgtgggcacc atccacggtc attggaatta ttaagaatga gaaatacaag
    25681 ggtgatatac tgttgggtaa aacattcacg gttgatccga tctccaaacg tcggcttgaa
    25741 aatatggggg aagaagataa gttctatatg aaagaccacc atgagccaat catcagtgag
    25801 gaagtctttg aaaaggcaca ggaaattcta aaccggagaa ataagaaccg gacgacagta
    25861 ggcaatggca agcgtgaaaa gtacagcagg aaatacgcat ttagctgtat gctggaatgt
    25921 ggtttctgtg gcagcacttt atcaagacgg aattggcaca gcagttcgga gtacagcaag
    25981 gttatctggc agtgtgtaac agcaacgaaa aaaggcaaga aattctgtcc agacagtaag
    26041 ggaataccag aaacagcaat cgaagaagcg ttcattgaaa gttaccgctt attatgcgat
    26101 aataacaaag acgtattaga cgaatttctg caaaggctgg atgatacatt gagtaacagc
    26161 acagtcaata aacagctatc caaaatcgaa aaggaaatca gtgcagtaga gggcaagaag
    26221 aataagctgg ttgatatgcg ccttgaagat agcatagata aagatacata cgaaacgaag
    26281 tatgctgcac ttatggaaaa agcggaacag cttgttgccg atcgtcagaa attgcaggaa
    26341 acagcggcta atgaaaaaga tattaagcga cgtttaaagg agtttaaatc tacgcttgaa
    26401 cagaatgagg ttttggatgt gtttgaccgc catgtatttg aaagtattgt agaaaaagta
    26461 attgtcggcg gctatgatga agatggaaaa aaagatccag cacagctcac gttcgtttat
    26521 aaaacaggtg tgaagaacag tgtagatggc agccgattta agccgcaaag aaaaaatgcg
    26581 agaggacgac ataggactga tgaattgtgt tcacatggaa gtaacgaggt tgataaaacg
    26641 tgttccgata ggagtaacga cacattgtga gactgtagtt aaacttatta gagaataaca
    26701 gggtttcaga cttttatatt gtgtcttaaa agtagatttg ccacctattt gccaccataa
    26761 ttatttttgg gtggcaaatt tattctacaa tgatttcaaa aatatttacc atctggtttc
    26821 tcatgttatt agttacatgt aaatatgtat ccatagttgt tgaagtttta gcatgtccga
    26881 gtatatgctg gatatctttt atattagtac cattttctaa taacatagta tcagggtttt
    26941 taaaataaag tgtgtattct tctagagtag tgataattaa aatatcaaat atcactatac
    27001 aaaggaaagt gcaccctttt tatgtttagc aaaaacgaaa tattaaaaaa acttattgaa
    27061 gaatatgatg tcaaaacaac tacagatatt caagatatgc taaaagattt atttacaaat
    27121 acaattcatc aaatatttcc attgtcgaat tttaacggtt taaacataat atattgactg
    27181 atataataaa atcatagaat attttagggg gaaatagatt atgtttaaga aaaagttaat
    27241 agctgttgca atgagtataa ctatgattag tgtagggagc ttttcgtatg ctcattcagg
    27301 aagaactgat tcatcaggag gtcatcgtga taataaaaat aaatctggat taggaagtta
    27361 tcactatcat tgtggtggtt atccagccca tttacataat aatggtggtt gtccttatac
    27421 tggaggagga agcagttctg gaacaacaac ttcggttaat aatgaagaaa agcaaaagag
    27481 gtctgttgga gaaaaaggat ataatcaagg gtatgaagat gggtataaag gaaattatag
    27541 ttcatcaaat tatagtggag attatagtga tacatatgaa tcaaagtact cagaaggata
    27601 tgaaaaaggt aaggctaaat tagaagagga agaaaaggtg gctaaagaga ctggatataa
    27661 tttagggctt acaggtgcta aatctaataa tacatatgaa aaagaagttt taaaaaatgc
    27721 ttatgatacc ggatattcaa ctggatacaa tgaatataag actaaaaaga tagaagaata
    27781 taaagctaaa gggatagagg atagcaataa agataaagaa aaaatgacat ttgaagaaaa
    27841 catagattct gaatttatag atgcttataa taatgcttat gacgaaatac aagaacaatt
    27901 aaaaaatgat tacactactc aaggatttga gagtgctatc aaaggagaaa gatttgacac
    27961 atcaactata ggtaatgtta aatatgctaa ttggtttaaa gaaggatatg ataatggtaa
    28021 gattaagtta cctaaagcaa aagaaagtgt atataatcaa ggttacaatg aagaagattt
    28081 tagtatacca tatgaaatga agtctattga aactaagtta aaaggtgtat atgatgaagg
    28141 tttagaaaaa agagaagaag agaaaagtag aaatgctact tatggggttg gagctggaac
    28201 agcagctgta gttgctggag tagtatataa aaataaaaaa cgtaaaaaga tatagatgct
    28261 agatatacca atgatgacaa gtgtataaca aatataattt taagtataaa tatttaaaat
    28321 atagaaggga aggttatatc tatgggattt aactttagga aaagcataaa tctaggagga
    28381 ggactcaaat taaatttagg taagaagagt gtaggtataa gtgctggtgt taaaggtgct
    28441 agagtgtcag ttaattcaaa aggaagaaaa tcagctacat tgagtatacc tggaactgga
    28501 atatcatata caaaaactag tacaaagaaa cgtaaaccta aataaatatt tgatatacta
    28561 agaaatagac tgttacaaat agtctatttt ttagtatata gatttaaaaa gtgacaaaat
    28621 tttgaaatat aaactaattt cataaaggaa aatattcttt tatgtagaat tataatattt
    28681 aagtaatatt ataaaattta taggaggatt tcattatgaa attaagcaaa acactattgg
    28741 caatagggat gtctgtttca ttattgattg ctagttgtcc aacatcaaac gctcttagtt
    28801 ctattaattc aataaaaggt acaaataagt atgaaacagc aggtttaata gcagataaac
    28861 aaaattatga tattgcaata cttattaatt ctgaaaatgg attatctgat ggattgtcag
    28921 caagtggatt gtcaggagct aaaaatgccc caatattgtt aactaagaaa gatacaatcc
    28981 cttcagaaac attaaaaaga ttagaaaagg taaaagaagt atatctaatt ggaggaaaaa
    29041 attcgatagg agcatcagtt cagaaaatat taagtgataa aaaaataagc ataaatagaa
    29101 taagtggaac tgatagaata gatacaagtc ataaagttgc aaaagaaata ggaagagtaa
    29161 gtacggttaa aaaagtaata ttaactaatg cttttaaagg cgaaccagat gctatgagtg
    29221 ttgcttctat agcagttaga gataaatctc caatagtatt aactgatgga aatactacaa
    29281 gttttgctac agatggatta gaaacttatg caattggtgg aaaagtcagt atgagtgata
    29341 agttaataaa tgaaactaaa gcaacaagaa taggtggagt agatagatac gatacaaata
    29401 aacaaataat aaataaattt tataatggct caaaagaatt ttacatagca agtgggactg
    29461 atttagttta ttctttagtt ggttctacaa ttgcacaaaa aacacctata gtgttagttg
    29521 gaaatggaag taataagagt atattaaaaa atgcaagtaa aataactgct attggaaata
    29581 ttgatgatgt tattataaaa caatgtttaa atataactaa taatgttggg gattcaaata
    29641 caggtattgt aaaagatact aattcaaata atacaaacaa accaagtaat gagcctagct
    29701 ctaataatcc tggattaact gataaaagta cagtatatgt aactcctaat ggaaaatcat
    29761 atcatctaac aaaaaattgt tctacactaa aaagaagtaa aacaataaat aaagtaacat
    29821 taaaacaagc taagtcacaa ggtaaaatag acccttgtaa tgtttgtgta aaataatgta
    29881 ttagccaaat atatattaaa aaagacaatt aattaagatt gtctttttta ttgaagaaat
    29941 ataaatttat attatgtatt attaaaaaga aa
//
LOCUS       DACTZW010000046        29244 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.046, whole genome shotgun sequence.
ACCESSION   DACTZW010000046 DACTZW010000000
VERSION     DACTZW010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 29244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29244
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.046"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            348..902
                     /gene="tcdR"
                     /locus_tag="JAM15_11120"
     CDS             348..902
                     /gene="tcdR"
                     /locus_tag="JAM15_11120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin sigma factor TcdR"
                     /protein_id="HAT6798802.1"
                     /translation="MQKSFYELIVLARNNSVDDLQEILFMFKPLVKKLSRVLHYEEGE
                     TDLIIFFIELIKNIKLSSFSEKSDAIIVKYIHKSLLNKTFELSRRYSKMKFNFVEFDE
                     NILNMKNNYQSKSVFEEDICFFEYILKELSGIQRKVIFYKYLKGYSDREISVKLKISR
                     QAVNKAKNRAFKKIKKDYENYFNL"
     gene            1233..8336
                     /gene="tcdB"
                     /locus_tag="JAM15_11125"
                     /gene_synonym="toxB"
     CDS             1233..8336
                     /gene="tcdB"
                     /locus_tag="JAM15_11125"
                     /gene_synonym="toxB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_070481156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdB"
                     /protein_id="HAT6798803.1"
                     /translation="MSLVNRKQLEKMANVRFRVQEDEYVAILDALEEYHNMSENTVVE
                     KYLKLKDINSLTDTYIDTYKKSGRNKALKKFKEYLVTEILELKNSNLTPVEKNLHFIW
                     IGGQINDTAINYINQWKDVNSDYNVNVFYDSNAFLINTLKKTIIESASNDTLESFREN
                     LNDPEFNHTAFFRKRMQIIYDKQQNFINYYKVQKEENPDLIIDDIVKTYLSNEYSKDI
                     DELNAYIEESLNKVTENSGNDVRNFEEFKTGEVFNLYEQELVERWNLAGASDILRVAI
                     LKNIGGVYLDVDMLPGIHPDLFKDINKPDSVKTAVDWEEMQLEAIMKYKEYIPEYTSK
                     HFDTLDEEVQSSFESVLASKSDKSEIFLPLGDIEVSPLEVKIAFAKGSIINQALISAK
                     DSYCSDLLIKQIQNRYKILNDTLGPIISQGNDFNTTMNNFGESLGAIANEENISFIAK
                     IGSYLRVGFYPEANTTITLSGPTIYAGAYKDLLTFKEMSIDTSILSSELRNFEFPKVN
                     ISQATEQEKNSLWQFNEERAKIQFEEYKKNYFEGALGEDDNLDFSQNTVTDKEYLLEK
                     ISSSTKSSERGYVHYIVQLQGDKISYEAACNLFAKNPYDSILFQKNIEDSEVAYYYNP
                     TDSEIQEIDKYRIPDRISDRPKIKLTLIGHGKAEFNTDIFAGLDVDSLSSEIETIIDL
                     AKADISPKSIEINLLGCNMFSYSVNVEETYPGKLLLRVKDKVSELMPSISQDSIIVSA
                     NQYEVRINSEGRRELLDHSGEWINKEESIIKDISSKEYISFNPKENKIIVKSKNLPEL
                     STLLQEIRNNSNSSDIELEEKVMLAECEINVISNIDTQVVEERIEEAKSLTSDSINYI
                     KNEFKLIESISDALYDLKQQNELEESHFISFEDISETDEGFSIRFIDKETGESIFVET
                     EKAIFSEYANHITEEISKLKDTIFDTVNGKLVKKVNLDATHEVNTLNAAFFIQSLIEY
                     NSSKESLSNLSVAMKVQVYAQLFSTGLNTITDAAKVVELVSTALDETIDLLPTLSEGL
                     PVIGTIIDGVSLGAAIKELSETSDPLLRQEIEAKIGIMAVNLTAATTAIITSSLGIAS
                     GFSILLVPLAGISAGIPSLVNNELILRDKATKVVDYFSHISLAESEGAFTSLDDKIMM
                     PQDDLVISEIDFNNNSITLGKCEIWRMEGGSGHTVTNDIDHFFSSPSITYREPHLSIY
                     DVLEVKKEELDLSKDLMVLPNAPNRVFGWETGWTPGLRSLENDGTKLLDRIRDQYEGQ
                     FYWRYFAFIADALITTLKPRYEDTNIRINLDSNTRSFIVPVITTEYIREKLSYSFYGS
                     GGTYALSLSQYNMNINIELNENDTWVIDVDNVVRDVTIESDKIKKGDLIENILSKLSI
                     EDNKIILDNHEINFSGTLNGGNGFVSLTFSILEGINAVIEVDLLSKSYKVLISGELKT
                     LMANSNSVQQKIDYIGLNSELQKNIPYSFMDDKGKENGFINCSTKEGLFVSELSDVVL
                     ISKVYMDNSKPLFGYCSNDLKDVKVITKDDVIILTGYYLKDDIKISLSFTIQDENTIK
                     LNGVYLDENGVAEILKFMNKKGSTNTSDSLMSFLESMNIKSIFINSLQSNTKLILDTN
                     FIISGTTSIGQFEFICDKDNNIQPYFIKFNTLETKYTLYVGNRQNMIVEPNYDLDDSG
                     DISSTVINFSQKYLYGIDSCVNKVIISPNIYTDEINITPIYEANNTYPEVIVLDTNYI
                     SEKINININDLSIRYVWSNDGSDFILMSTDEENKVSQVKIRFTNVFKGNTISDKISFN
                     FSDKQDVSINKIISTFTPSYYVEALLNYDLGLISLYNEKFYINNFGMMVSGLVYINDS
                     LYYFKPPIKNLITGFTTIGDDKYYFNPDNGGAASVGETIIDGKNYYFSQNGVLQTGVF
                     STEDGFKYFAPADTLDENLEGEAIDFTGKLTIDENVYYFGDNYRAAIEWQTLDDEVYY
                     FSTDTGRAFKGLNQIGDDKFYFNSDGIMQKGFVNINDKTFYFDDSGVMKSGYTEIDGK
                     YFYFAENGEMQIGVFNTADGFKYFAHHDEDLGNEEGEALSYSGILNFNNKIYYFDDSF
                     TAVVGWKDLEDGSKYYFDEDTAEAYIGLSLINDGQYYFNDDGIMQVGFVAINDKVFYF
                     SDSGIIESGVQNIDDNYFYIDEKGIVQIGVFDTSDGYKYFAPANTVNDNIYGQAVEYS
                     GLVRVGEDVYYFGETYTIETGWIYDMENESDKYYFDPETKKACKGINTIHDIKYYFDE
                     TGIMRTGLITFENNHYYFNEDGEMQYGYLNIEDKMFYFSEDGIMQIGVFNTPDGFKYF
                     AHQNTLDENFEGESINYTGWLDLDEKRYYFTDEYIAATGSVIIDGEEYYFDPDTAQLV
                     ISE"
     gene            8458..8958
                     /gene="tcdE"
                     /locus_tag="JAM15_11130"
     CDS             8458..8958
                     /gene="tcdE"
                     /locus_tag="JAM15_11130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin-like glycosylating toxin export protein
                     TcdE"
                     /protein_id="HAT6798804.1"
                     /translation="MHSSSPFYISNGNKIFFYINLGGVMNMTISFLSEHIFIKLVILT
                     ISFDTLLGCLSAIKSRKFNSSFGIDGGIRKVAMIACIFFLSVVDILTKFNFLFMLPQD
                     CINFLRLKHLGISEFFSILFILYESVSILKNMCLCGLPVPKRLKEKIAVLLDAMTDEM
                     NAKDEK"
     gene            9037..9198
                     /locus_tag="JAM15_11135"
     CDS             9037..9198
                     /locus_tag="JAM15_11135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798805.1"
                     /translation="MKLIMKTREQMPRDTQVLNTYNFEASVHYYMDDKVVYQTLVHKD
                     GAWSVGKIY"
     gene            9287..9469
                     /locus_tag="JAM15_11140"
     CDS             9287..9469
                     /locus_tag="JAM15_11140"
                     /inference="COORDINATES: protein motif:HMM:NF022413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798806.1"
                     /translation="MRDEGQNDRENKYQTLINDLIDSLKVIGKIYKEIKTLKKYKICL
                     QITIRQSPYLIEESIN"
     gene            9686..17818
                     /gene="tcdA"
                     /locus_tag="JAM15_11145"
                     /gene_synonym="toxA"
     CDS             9686..17818
                     /gene="tcdA"
                     /locus_tag="JAM15_11145"
                     /gene_synonym="toxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021394011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdA"
                     /protein_id="HAT6798807.1"
                     /translation="MSLISKEELIKLAYSIRPRENEYKTILTNLDEYNKLTTNNNENK
                     YLQLKKLNESIDVFMNKYKNSSRNRALSNLKKDILKEVILIKNSNTSPVEKNLHFVWI
                     GGEVSDIALEYIKQWADINAEYNIKLWYDSEAFLVNTLKKAIVESSTTEALQLLEEEI
                     QNPQFDNMKFYKKRMEFIYDRQKRFINYYKSQINKPTVPTIDDIIKSHLVSEYNRDET
                     LLESYRTNSLRKINSNHGIDIRANSLFTEQELLNIYSQELLNRGNLAAASDIVRLLAL
                     KNFGGVYLDVDMLPGIHSDLFKTIPRPSSIGLDRWEMIKLEAIMKYKKYINNYTSENF
                     DKLDQQLKDNFKLIIESKSEKSEIFSKLENLNVSDLEIKIAFALGSVINQALISKQGS
                     YLTNLVIEQVKNRYQFLNQHLNPAIESDNNFTDTTKIFHDSLFNSATAENSMFLTKIA
                     PYLQVGFMPEARSTISLSGPGAYASAYYDFINLQENTIEKTLKASDLIEFKFPENNLS
                     QLTEQEINSLWSFDQASAKYQFEKYVRDYTGGSLSEDNGVDFNKNTALDKNYLLNNKI
                     PSNNVEEAGSKNYVHYIIQLQGDDISYEATCNLFSKNPKNSIIIQRNMNESAKSYFLS
                     DDGESILELNKYRIPERLKNKEKVKVTFIGHGKDEFNTSEFARLSVDSLSNEISSFLD
                     TIKLDISPKNVEVNLLGCNMFSYDFNVEETYPGKLLLSIMDKITSTLPDVNKDSITIG
                     ANQYEVRINSEGRKELLAHSGKWINKEEAIMSDLSSKEYIFFDSIDNKLKAKSKNIPG
                     LASISEDIKTLLLDASVSPDTKFILNNLKLNIESSIGDYIYYEKLEPVKNIIHNSIDD
                     LIDEFNLLENVSDELYELKKLNNLDEKYLISFEDISKNNSTYSVRFINKSNGESVYVE
                     TEKEIFSKYSEHITKEISTIKNSIITDVNGNLLDNIQLDHTSQVNTLNAAFFIQSLID
                     YSSNKDVLNDLSTSVKVQLYAQLFSTGLNTIYDSIQLVNLISNAVNDTINVLPTITEG
                     IPIVSTILDGINLGAAIKELLDEHDPLLKKELEAKVGVLAINMSLSIAATVASIVGIG
                     AEVTIFLLPIAGISAGIPSLVNNELILHDKATSVVNYFNHLSESKKYGPLKIEDDKIL
                     VPIDDLVISEIDFNNNSIKLGTCNILAMEGGSGHTVTGNIDHFFSSPYISSHIPSLSV
                     YSAIGIKTENLDFSKKIMMLPNAPSRVFWWETGAVPGLRSLENDGTKLLDSIRDLYPG
                     KFYWRFYAFFDYAITTLKPVYEDTNIKIKLDKDTRNFIMPTITTDEIRNKLSYSFDGA
                     GGTYSLLLSSYPISMNINLSKDDLWIFNIDNEVREISIENGTIKKGNLIEDVLSKIDI
                     NKNKLIIGNQTIDFSGDIDNKDRYIFLTCELDDKISLIIEINLVAKSYSLLLSGDKNY
                     LISNLSNTIEKINTLGLDSKNIAYNYTDESNNKYFGAISKTSQKSIIHYKKDSKNILE
                     FYNGSTLEFNSKDFIAEDINVFMKDDINTITGKYYVDNNTDKSIDFSISLVSKNQVKV
                     NGLYLNESVYSSYLDFVKNSDGHHNTSNFMNLFLNNISFWKLFGFENINFVIDKYFTL
                     VGKTNLGYVEFICDNNKNIDIYFGEWKTSSSKSTIFSGNGRNVVVEPIYNPDTGEDIS
                     TSLDFSYEPLYGIDRYINKVLIAPDLYTSLININTNYYSNEYYPEIIVLNPNTFHKKV
                     NINLDSSSFEYKWSTEGSDFILVRYLEESNKKILQKIRIKGILSNTQSFNKMSIDFKD
                     IKKLSLGYIMSNFKSFNSENELDRDHLGFKIIDNKTYYYDEDSKLVKGLININNSLFY
                     FDPIESNLVTGWQTINGKKYYFDINTGAASTSYKIINGKHFYFNNNGVMQLGVFKGPD
                     GFEYFAPANTQNNNIEGQAIVYQSKFLTLNGKKYYFDNDSKAVTGWRIINNEKYYFNP
                     NNAIAAVGLQVIDNNKYYFNPDTAIISKGWQTVNGSRYYFDTDTAIAFNGYKTIDGKH
                     FYFDSDCVVKIGVFSGSNGFEYFAPANTYNNNIEGQAIVYQSKFLTLNGKKYYFDNNS
                     KAVTGWQTIDSKKYYFNTNTAEAATGWQTIDGKKYYFNTNTAEAATGWQTIDGKKYYF
                     NTNTSIASTGYTIINGKHFYFNTDGIMQIGVFKGPNGFEYFAPANTDANNIEGQAILY
                     QNKFLTLNGKKYYFGSDSKAITGWQTIDGKKYYFNPNNAIAATHLCTINNDKYYFSYD
                     GILQNGYITIERNNFYFDANNESKMVTGVFKGPNGFEYFAPANTHNNNIEGQAIVYQN
                     KFLTLNGKKYYFDNDSKAVTGWQTIDSKKYYFNLNTAVAVTGWQTIDGEKYYFNLNTA
                     EAATGWQTIDGKRYYFNTNTYIASTGYTIINGKHFYFNTDGIMQIGVFKGPDGFEYFA
                     PANTHNNNIEGQAILYQNKFLTLNGKKYYFGSDSKAVTGLRTIDGKKYYFNTNTAVAV
                     TGWQTINGKKYYFNTNTYIASTGYTIISGKHFYFNTDGIMQIGVFKGPDGFEYFAPAN
                     TDANNIEGQAIRYQNRFLYLHDNIYYFGNDSKAATGWATIDGNRYYFEPNTAMGANGY
                     KTIDNKNFYFRNGLPQIGVFKGPNGFEYFAPANTDANNIDGQAIRYQNRFLHLLGKIY
                     YFGNNSKAVTGWQTINGKVYYFMPDTAMAAAGGLFEIDGVIYFFGVDGVKAPGIYG"
     gene            complement(18153..18731)
                     /locus_tag="JAM15_11150"
     CDS             complement(18153..18731)
                     /locus_tag="JAM15_11150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin regulator"
                     /protein_id="HAT6798808.1"
                     /translation="MFFGNISSPACSEDHEEVISNQTSVIDSQKTEIETLNSKLSDAE
                     PWFKMKDDEKKAIEAENQRKAEEAKKAEEAKKAEEQRKKEEEEKKGYDTGITYDQLAR
                     TPDDYKYKKVKFEGKVIQVIEDGDEVQIRLAVSGNYDKVVLCSYKKSITPSRVLEDDY
                     ITIRGISAGTITYESTMGGNITIPGIAVEKIN"
     gene            19268..19513
                     /locus_tag="JAM15_11155"
     CDS             19268..19513
                     /locus_tag="JAM15_11155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pathogenicity locus"
                     /protein_id="HAT6798809.1"
                     /translation="MGELQKIPGVGKATEKSLIMLGYTTIKSLKDANPAQMYEKECLM
                     RGQHIDRCQLYVYRCAVYFASTENPEPEKLKWWYWKD"
     gene            complement(19730..19999)
                     /locus_tag="JAM15_11160"
     CDS             complement(19730..19999)
                     /locus_tag="JAM15_11160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HAT6798810.1"
                     /translation="MFESRCGVCCDSCTKKEQVNCTGCPTMEKPFWGGECKVKTCCES
                     KELNHCGECDTFPCDMLLNKGKDQGFDPMVNIGQCRKWLEETVSN"
     gene            complement(20211..20474)
                     /locus_tag="JAM15_11165"
     CDS             complement(20211..20474)
                     /locus_tag="JAM15_11165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798811.1"
                     /translation="MKYSKGFKLIYSLVEYSKRFKVIYDVMKYSKEFKLIYSLVEYSK
                     RFKLIYSVMKYSKEFKLIYSLVEYSKRFKAIYNAVKYIQGDLK"
     gene            complement(21072..21809)
                     /locus_tag="JAM15_11170"
     CDS             complement(21072..21809)
                     /locus_tag="JAM15_11170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAT6798812.1"
                     /translation="MLRKSVLGEILKLKNSFIWYVLLALPLISVLIGSGNFYLNQGIL
                     KKEWYSLWTQVSLFYGEFFFPILIAIFCAYICRLEHMNHNWNNVMTLPVNLKNIFLSK
                     LTVVSILTAITQVFFVIFYIVAGNMFGFSGSVPKELTGWIAKGWIISISIASIQLYMS
                     IKIRSFATPIGISLCLSLFGMGLIVAKPAVGIFFPYSMLGSAMGVIKQSALNVNDTIV
                     TICVAFITTIVFSEIANRNFRKNDVIS"
     gene            complement(21821..22582)
                     /locus_tag="JAM15_11175"
     CDS             complement(21821..22582)
                     /locus_tag="JAM15_11175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAT6798813.1"
                     /translation="MKYLGLEFYKLKRKKIILMTFLFVAVEIMWCIVNSNRAITRNPD
                     MLGGFEYSYMLMSFASLNGLFFPILISIITSRISDIEHKGDTWKLLKSSVTSLNSIYL
                     SKFLCSAILVSVPVLMQVLSIVLFGHFRGVIESISVSLLLKYTLGTILVSIAIIALHL
                     WIATVIPNQMIAITFGMIGSFIGLTSGLFYQGIRRLFIWSYYLELSPLSYAYDNVLGS
                     SVYRIDMNFSITILVFLIGMLIYYIGRNHLLKKEV"
     gene            complement(22582..23496)
                     /locus_tag="JAM15_11180"
     CDS             complement(22582..23496)
                     /locus_tag="JAM15_11180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6798814.1"
                     /translation="MEMIIRTQRLSKEYNKIFRVKDIDLRVPQGAVYGFLGPNGAGKS
                     TTLKMLLGLAKPTQGNINILGKELNEKNRISILKDIGSLIESPSYYGHLTGLENMTIM
                     QRLLDLPKKNVNEALKIVRLENQKNKKVSQYSLGMKQRLGIAMAIMKFPKLLILDEPT
                     NGLDPAGIEEIRELIKSLPEKYGMTVLISSHLLSEIDQIATSIGIINHGELVFQDSIK
                     ELHNRGQSQIAIKAKNVVSAQKLLNTKGYMSLIQNGYLTIENLKDSDVAKINGMLVHS
                     NIDVFRIEEHKKSLEDIFLELTGKAVTL"
     gene            23667..24374
                     /locus_tag="JAM15_11185"
     CDS             23667..24374
                     /locus_tag="JAM15_11185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6798815.1"
                     /translation="MESIKDKKILVVDDHKELLKMIDEILRKEGFSRVFLASSYEEAV
                     RVFRNVKPDCAILDVVLPDGDGFSIMRKIRETSKIPVIFLSARGEDEDRLIGLGLGAD
                     DYIVKPFLPKELTLRLVGILNRVYVPIEEEELPVFKLGDSVVVNLNSACVEKDGQEIS
                     LTAKEHSLLLKLYENKGRIVTNDSLCQAIWGDDMYGYENTLMVHVRRVREKIEKTPST
                     PKHLITVRGLGYKLMIN"
     gene            24419..25825
                     /locus_tag="JAM15_11190"
     CDS             24419..25825
                     /locus_tag="JAM15_11190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAT6798816.1"
                     /translation="MDSVKYILRRFIGSSILISLLFIVLNIAGFLLFSYMLFVSKYSD
                     NLDTSDSREIKSNLIMIEDNLILKDGKFILDDSSKEVLHKNKVWAMLIDNNGDRIWGF
                     DLPKEIPSHYTLTDVAKFSRFFLKDYPVYVWEHPNGILVTGYPKDKYTKFNLTYTIKE
                     IEQFPMLIIGMFLVNAIVTFLIALFIGLKMVKSIKPIITGIKLMSKGEPVLLQEKGIL
                     SDISKSINTVSKELQMKDEKLRKKEEARSNWIAGISHDIRTPLSMIIGYAGELEESSS
                     LSNREQEQVSIICNQGVKIRELVNDLNLVSKLEYNMQALNCDKIRVSAFLRELISEFI
                     NNNLDNDFYVELDILNEDIIIDADKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDLD
                     FCYIIVEDDGKGMSQEKINSLLKSQNGLSEAYAKGQNHGLGILIVAGIINAHRGKLDI
                     MSIDSQGLKTILKLPLIK"
     gene            27551..27940
                     /locus_tag="JAM15_11195"
     CDS             27551..27940
                     /locus_tag="JAM15_11195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HAT6798817.1"
                     /translation="MTIKKLPQSELKIMKFIWKSDSKVTSRDIVLGMEQKYQWKQTTT
                     LTLLSRLVVKRFLNSQKIDKYTHYEVLIKEKEYIGVETRDFFRNIHDSSIKSLLLSLH
                     ENINLSKDDILLIEEWIKNLKEEEKDV"
     gene            28680..29150
                     /locus_tag="JAM15_11200"
     CDS             28680..29150
                     /locus_tag="JAM15_11200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HAT6798818.1"
                     /translation="MKYQVSLLAVKDIEVSKKFYKELFEQEIELDLGKNVTFKGGFAI
                     QEDFAWLTGINPDTIIQKSNNMELYFEVDDFDEFIEKLNYYKDVEFVHKPLKHEWQQR
                     VVRIYDPDKHIIEIGESMEVIARRYLSEGYSVEETSKIIQHPIEFVKQCENSKE"
BASE COUNT        11631 a         3257 c         4443 g         9913 t
ORIGIN      
        1 cttaaaaatt gaactatttt aaaatctagt tatagtttac aaaaaaactg aaaattaata
       61 aaaaagaaat tagtatataa aatcatgtca tatggatttt ccctatttta ttctaataga
      121 atgatttatt tttacaatac tttattaata taaaatttct tgctaaaata ctttatttaa
      181 taggaaaaga ttactaatta attattaaat taatgtattt ataatgtata ttttcataca
      241 aaatttaatt tattttccta ctatgcaatt ataatgactg atttaatgca tatgttgtca
      301 aaatttttaa aaaaatcatc attataaata taagagagga tgattttatg caaaagtctt
      361 tttacgaatt aattgtttta gcaagaaata actcagtaga tgatttgcaa gaaattttat
      421 ttatgtttaa gccattagta aaaaaactta gtagagtttt acattatgaa gagggagaaa
      481 cagatttaat aatatttttt attgaattaa taaaaaatat taaattaagt agcttttcag
      541 aaaaaagcga tgctattata gtcaaatata ttcataaatc attattgaat aagacttttg
      601 agttgtctag aagatattct aaaatgaagt ttaattttgt agaatttgat gaaaatatct
      661 taaatatgaa aaataattat caaagtaagt ctgtttttga ggaagatatt tgttttttcg
      721 aatatatttt gaaagaatta tctggtattc aaagaaaagt tattttttat aaatatttaa
      781 aaggatattc tgatagagaa atatcagtga aattaaaaat atctagacaa gctgttaata
      841 aggctaaaaa tagagcattt aaaaaaataa aaaaagacta tgaaaattat tttaacttgt
      901 aattaatgaa tttaaagaaa tatttacaat agaaatcaaa ttttagaatt aactttattg
      961 taaaatcaat aacttaatct aagaatatct taatttttat attttatata gaacaatgtt
     1021 tacatattta tttcggacaa cgtctttatt taatagaaga gcaaattaat cagctgagtg
     1081 tcttcaattt aaaatgttag gaagtgaatg tatatgaaaa cctaagtaga tattagtata
     1141 ttttataaat agaaaggagg atatataaaa gagttttagc atttagatgt aaaaatattt
     1201 aataaaaata ttatagtaaa ggagaaaatt ttatgagttt agttaataga aaacagttag
     1261 aaaaaatggc aaatgtaaga tttcgtgttc aggaagatga atatgtagca atattagatg
     1321 cattagaaga atatcataat atgtcagaaa atactgtagt tgaaaagtat ctaaaattaa
     1381 aagatataaa cagtttaaca gatacctata tagatacata taaaaaatct ggccgaaata
     1441 aagccttaaa aaaatttaaa gagtacttag ttacagagat attagaatta aaaaatagca
     1501 atttaactcc agtcgagaaa aatttacatt ttatatggat tggagggcaa ataaatgata
     1561 ctgctattaa ttatataaat caatggaaag atgtaaatag tgactataat gttaatgttt
     1621 tttatgatag taatgcattt ttgataaaca cattgaaaaa aactataata gaatcagcat
     1681 caaatgatac tcttgaatca tttagagaaa atttaaatga tcctgaattt aaccacactg
     1741 catttttcag aaaacgtatg caaataatct atgataaaca gcaaaatttc ataaattact
     1801 ataaagttca aaaagaagaa aatcctgacc ttataattga tgatattgta aagacatatc
     1861 tttcaaacga gtattcaaag gatatagatg aacttaatgc ttatattgaa gagtcattaa
     1921 acaaagtcac agaaaatagt ggaaatgatg ttagaaactt tgaagaattt aaaactggag
     1981 aagtattcaa tttatatgaa caagagttag tagaaagatg gaatcttgct ggtgcatctg
     2041 atatattaag agtcgctata ttgaaaaata ttggtggagt ctatctagat gttgatatgt
     2101 taccaggaat acacccagat ttatttaaag atataaataa gcctgattca gtaaagacag
     2161 ctgtagattg ggaagagatg cagttagaag ccataatgaa atataaagaa tatataccag
     2221 aatatacttc aaaacatttt gatacattgg atgaagaagt tcaaagtagc tttgaatctg
     2281 ttctagcttc taagtctgat aagtcagaaa tatttttacc actaggagat atagaggtat
     2341 cacctttaga agtaaaaatt gcatttgcca aaggttctat tataaatcaa gctctaattt
     2401 ctgcaaaaga ctcatattgt agtgacttac taataaaaca aatccaaaac agatataaga
     2461 tactgaatga tactttaggt ccaattatta gtcaaggtaa tgattttaat actacaatga
     2521 acaattttgg tgaaagtttg ggagctatag ctaatgaaga gaatataagt tttatagcaa
     2581 aaatcggaag ttatttaagg gttggatttt atcctgaagc taatactaca attactttaa
     2641 gtggtcctac aatatatgca ggagcttata aagatttatt aacatttaaa gagatgagca
     2701 tagatacttc tatattgtca tctgagttaa gaaattttga atttcctaag gttaatatat
     2761 ctcaagcaac agaacaagag aaaaatagct tatggcaatt taacgaagaa agagctaaaa
     2821 ttcaatttga agaatacaag aaaaattatt ttgaaggtgc acttggagaa gatgataatc
     2881 ttgatttttc tcaaaataca gtaactgaca aagaatatct tttagaaaaa atttcttcat
     2941 caacaaagag ttcagaaaga ggatatgttc attatattgt tcaattacaa ggagataaaa
     3001 ttagctatga agcagcatgt aacttatttg caaaaaatcc ttatgacagt atactatttc
     3061 aaaaaaatat agaagattca gaagtagcat attactataa tcctacagat agtgaaatac
     3121 aagaaattga taagtataga attcctgata gaatctctga tagacctaag attaaattga
     3181 cacttattgg tcatggcaaa gctgagttta atactgatat atttgcaggt cttgatgtgg
     3241 attcattatc ttcagaaata gaaacaataa tagatttagc taaagcagat atttctccta
     3301 aatctataga aataaactta ctgggatgta acatgtttag ctattctgta aatgtagaag
     3361 agacttatcc tgggaaatta ttacttagag ttaaagataa agtatcagag ttaatgccat
     3421 ctataagtca agactctatt atagtaagtg caaatcaata tgaagttaga ataaatagtg
     3481 aaggaagaag agaattattg gatcattctg gtgaatggat aaataaagaa gaaagtatta
     3541 taaaggatat ttcatcaaaa gaatatatat catttaatcc taaagaaaat aaaattatag
     3601 taaaatctaa aaatttacct gaattatcta cattattaca agaaattaga aacaattcta
     3661 attcaagtga tattgaacta gaagaaaaag taatgttagc agaatgtgag ataaatgtta
     3721 tttcaaatat agatacacaa gtggtagaag aaaggattga agaagctaaa agcttaactt
     3781 ctgactctat taattatata aagaatgaat ttaaactaat agaatctatt tctgatgcac
     3841 tatacgattt aaaacaacag aatgaattag aagagtctca ttttatatct tttgaggata
     3901 tatcggagac tgatgaaggc tttagtataa gatttattga taaagaaact ggagaatcta
     3961 tatttgtaga aactgaaaag gcaatattct ctgaatatgc taatcatata actgaagaaa
     4021 tttctaagtt aaaagatact atatttgata ctgtaaatgg taagttggtg aaaaaagtaa
     4081 atttagatgc tacacatgaa gtgaatactt taaatgctgc attttttata caatcattaa
     4141 tagaatataa tagttctaaa gaatctctta gtaatttaag tgtagcaatg aaagttcaag
     4201 tttatgctca attatttagt actggtttga ataccattac agatgcagcc aaagttgttg
     4261 aattagtatc aactgcacta gatgaaacta tagatttact tcctacatta tctgaaggat
     4321 tacctgtaat tggaactatc atagatggtg taagtttagg tgcagcaatc aaagagctaa
     4381 gtgaaacaag tgacccatta ttaagacaag aaatagaagc taagataggt ataatggcag
     4441 taaatttaac agcagctaca actgcaataa ttacttcatc tttaggaata gctagtggat
     4501 ttagtatact tttagttcct ttagcaggaa tttcagcagg tataccaagt ttagtaaaca
     4561 atgagcttat cctaagagat aaagcaacaa aagttgtaga ttattttagt catatatcat
     4621 tagctgagtc tgaaggagca tttacttcat tagatgataa aataatgatg ccacaagatg
     4681 atttagtaat atctgagata gactttaata acaattcaat aactttaggt aaatgtgaaa
     4741 tatggagaat ggaaggtggt tcaggtcata ctgtaactaa tgatatagat cacttctttt
     4801 catcaccatc aataacatat agagaaccac atttatctat atatgatgta ttagaagtta
     4861 aaaaagaaga acttgatttg tcaaaagatt taatggtatt acctaatgcc ccaaatagag
     4921 tgtttggctg ggaaacagga tggacaccag gtttaagaag cttagaaaat gatggtacaa
     4981 aactgttaga ccgtataaga gaccagtatg aaggtcagtt ttattggaga tattttgctt
     5041 ttatagctga tgctttaata acaacattaa aaccaagata tgaagatact aatataagaa
     5101 taaatttaga tagtaatact agaagcttta tagtcccagt gataactaca gaatatataa
     5161 gagagaaatt atcatattct ttttatggtt ctggaggaac ttatgcatta tctctttctc
     5221 aatacaatat gaatataaac atagaattaa atgaaaatga tacttgggtt atagatgtcg
     5281 acaatgtcgt aagagatgtc actatagaat ctgataaaat taaaaaagga gatttaatag
     5341 agaatatttt atctaaatta agtattgaag acaataaaat tattttagat aatcatgaaa
     5401 ttaatttctc tggaacatta aatggaggta atggatttgt atctttaaca ttctcaatct
     5461 tagaaggaat aaatgcagtt atagaagttg atttattatc taaatcatat aaagttctta
     5521 tttctggtga actaaaaaca ttgatggcaa attcaaattc tgttcaacag aaaatagatt
     5581 atataggatt gaacagcgaa ttacaaaaaa atatacctta tagttttatg gatgataaag
     5641 gaaaagaaaa tggatttatt aattgttcta caaaagaagg tttatttgta tctgaattat
     5701 ctgatgtagt tcttataagt aaagtttata tggacaatag taaacctcta tttggatatt
     5761 gtagtaatga tttgaaagat gttaaagtca taactaaaga tgacgttatt atattaacag
     5821 gatattattt aaaagatgat ataaaaatct ctctttcttt tactatacaa gatgaaaata
     5881 ctataaaatt aaatggagta tatttagatg aaaatggagt agctgaaata ttgaaattta
     5941 tgaataaaaa aggtagtaca aatacttcag attctttaat gagcttttta gaaagtatga
     6001 atataaaaag tattttcata aattccttac aatctaatac taagcttata ttagatacta
     6061 attttataat aagtggtact acttctattg gtcaatttga gtttatttgt gataaagata
     6121 ataatataca accatatttc attaagttta atacactaga aactaaatat actctatatg
     6181 taggtaatag acaaaatatg atagtagaac caaattatga tttagatgat tctggagata
     6241 tatcttcaac tgtcattaat ttttctcaga aataccttta tggaatagac agttgtgtta
     6301 ataaagttat aatttcgcca aatatatata cagatgaaat aaacataaca cctatatatg
     6361 aagcaaataa tacttatcca gaagtgattg tattagatac aaattatata agtgaaaaaa
     6421 tcaatattaa tatcaatgat ttatctatac gatatgtatg gagtaatgat ggaagtgatt
     6481 ttattcttat gtcaactgat gaagagaaca aggtatcaca agttaaaata agatttacta
     6541 atgtttttaa aggtaatact atatcagata agatatcttt taattttagt gataagcaag
     6601 atgtatctat aaataaaatt atttcaacat ttacaccttc atattatgtg gaagcattac
     6661 ttaattatga tttaggtctg atttctttat acaatgagaa attttatatt aataactttg
     6721 gaatgatggt gtctggatta gtatatatta atgattcatt atattatttc aagccaccaa
     6781 taaagaactt gataactgga tttacaacta taggtgatga taaatactac tttaatccag
     6841 ataatggtgg agctgcttca gtcggagaaa caataattga tggcaaaaac tactacttca
     6901 gccaaaatgg agtgttacaa acaggtgtat ttagtacaga agatggattt aaatattttg
     6961 ctccagcaga tacacttgat gaaaatctag agggggaagc aattgatttt actggcaaac
     7021 taactattga tgaaaatgtt tattattttg gagataatta tagagcagct atagaatggc
     7081 aaacattaga tgatgaagtg tactatttta gtacagatac aggtagagct tttaaagggc
     7141 taaatcaaat aggtgatgat aaattctatt tcaactctga tggtattatg caaaaaggat
     7201 ttgttaatat aaatgataag acattctatt ttgatgattc tggtgtgatg aagtcaggat
     7261 atactgaaat agatggaaaa tatttttact ttgctgagaa tggagaaatg caaataggag
     7321 tatttaatac agcagatgga tttaaatatt ttgctcatca tgatgaagat ttaggaaatg
     7381 aagaaggtga agcactttca tattctggta tacttaattt taacaataag atttattatt
     7441 ttgatgattc atttacagca gtagttggat ggaaggattt agaagatggt tcaaaatatt
     7501 actttgatga agatacagca gaagcatata taggtttatc attaataaat gatggtcaat
     7561 attattttaa tgatgatgga attatgcaag ttggatttgt tgctataaat gataaagtct
     7621 tctacttctc tgattctggg attatagaat ctggagtaca aaacatagat gataattatt
     7681 tctatataga tgagaagggt atagttcaaa ttggtgtatt tgatacttca gatggatata
     7741 aatactttgc accagctaat actgtaaatg ataatattta cggacaagca gttgaatata
     7801 gtggtttagt tagagttggt gaagatgtat attattttgg agaaacatat acaattgaga
     7861 ctggatggat atatgatatg gaaaatgaaa gtgataaata ttatttcgat ccagaaacta
     7921 aaaaagcatg taaaggtatt aatacaattc atgatataaa atattatttt gatgagactg
     7981 gcataatgag aacaggtctt ataacatttg aaaataacca ttactatttt aatgaagatg
     8041 gtgaaatgca atatggttat ctaaatatag aagataagat gttctacttt agtgaagatg
     8101 gtattatgca gattggagta tttaatacac cagatggatt taaatatttt gcacatcaaa
     8161 atactttaga tgagaatttt gagggagaat caataaacta tactggttgg ttagatttag
     8221 atgaaaagag atattatttt acagatgaat atattgcagc aactggttca gttattattg
     8281 atggtgagga gtattatttt gatcctgata cagctcaatt agtgattagt gaatagataa
     8341 aaatacgtta aatatatcct cttatactta aatatataaa aataaacaaa atgatacact
     8401 acataaagtg ttctatctaa tatgaagatt taccaataaa aaggtgaact atgatgaatg
     8461 cacagtagtt caccttttta tatttctaat ggtaacaaaa tattttttta tataaaccta
     8521 ggaggcgtta tgaatatgac aatatctttt ttatcagagc atatatttat aaagttagta
     8581 attttaacta tatcatttga tacattatta ggatgtttaa gtgcaataaa aagtcgtaaa
     8641 tttaattcta gttttggaat agatggagga atcagaaaag tagcaatgat agcatgtata
     8701 ttttttttat cagtagttga cattcttaca aagtttaact ttttatttat gttaccacaa
     8761 gattgtatca attttttaag actaaaacat cttggaatat ctgaattttt ctctatttta
     8821 tttattttat atgaaagtgt aagcatatta aaaaatatgt gcttatgtgg attaccagta
     8881 cctaagagat taaaggaaaa aatagcagtt ttactagatg caatgacaga tgaaatgaat
     8941 gctaaggatg aaaagtaagt aatggtagat ataataaaga tattaacaaa taaaaagtgt
     9001 tatccaaata agaatagctg aaagttatca taattcatga aactgataat gaaaacgagg
     9061 gagcagatgc caagagacac acaagtatta aatacatata atttcgaagc aagtgttcat
     9121 tactatatgg atgacaaggt agtatatcaa acattggttc acaaagatgg tgcatggtca
     9181 gttggtaaaa tctattaagc tacattagtt acagatatca caaactataa tagttaaaca
     9241 tagaaatatg tgtaaattgt gatggaaatt attcaaaaac acaaaaatac gtgatgaagg
     9301 acaaaatgat agagaaaata agtatcaaac cttaataaat gatttaattg atagtttaaa
     9361 agttatagga aaaatatata aagaaataaa aacattaaaa aaatataaga tatgtttaca
     9421 aattactatc agacaatctc cttatctaat agaagagtca attaactaat tgagtatctt
     9481 taaattgaaa tgttaggaag tgatttaaat atgaaaactt aaattataaa aaatcaatat
     9541 taatttatct ttaaaaaata gaaaggagtg tataagattt attttcaaag tttaaaaaca
     9601 agaaaatcaa tttaaatttc agaaggaata aatgtggtta tagaagtgga tttattatca
     9661 aaaataatag tactaggagg tttttatgtc tttaatatct aaagaagagt taataaaact
     9721 cgcatatagc attagaccaa gagaaaatga gtataaaact atattaacta atttagacga
     9781 atataataag ttaactacaa acaataatga aaataaatat ttacaattaa aaaaactaaa
     9841 tgaatcaatt gatgttttta tgaataaata taaaaattca agcagaaata gagcactctc
     9901 taatctaaaa aaagatatat taaaagaagt aattcttatt aaaaattcca atacaagtcc
     9961 tgtagaaaaa aatttacatt ttgtatggat aggtggagaa gtcagtgata ttgctcttga
    10021 atacataaaa caatgggctg atattaatgc agaatataat attaaactgt ggtatgatag
    10081 tgaagcattc ttagtcaata cactaaaaaa ggctatagtt gaatcttcta ccactgaagc
    10141 attacagcta ctagaggaag agattcaaaa tcctcaattt gataatatga aattttacaa
    10201 aaaaaggatg gaatttatat atgatagaca aaaaaggttt ataaattatt ataaatctca
    10261 aatcaataaa cctacagtac ctacaataga tgatattata aagtctcatc tagtatctga
    10321 atataataga gatgaaactt tattagaatc atatagaaca aattctttga gaaaaataaa
    10381 tagtaatcat gggatagata tcagggctaa tagtttgttt acagaacaag agttattaaa
    10441 tatttatagt caggagttgt taaatcgtgg gaatttagct gcagcatctg acatagtaag
    10501 attattagcc ctaaaaaatt ttggcggagt atatttagat gttgatatgc ttccaggtat
    10561 tcactctgat ttatttaaaa caatacctag acctagctct attggactag accgttggga
    10621 aatgataaaa ttagaggcta ttatgaagta taaaaaatat ataaataatt atacatcaga
    10681 aaactttgat aaacttgatc aacaattaaa agataatttt aaactcatta tagaaagtaa
    10741 aagtgaaaaa tctgagatat tttctaaatt agaaaattta aatgtatctg atcttgaaat
    10801 taaaatagct ttcgctttag gcagtgttat aaatcaagcc ttgatatcaa aacaaggttc
    10861 atatcttact aacctagtaa tagaacaagt aaaaaataga tatcaatttt taaaccaaca
    10921 ccttaaccca gccatagagt ctgacaataa cttcacagat actactaaga tttttcatga
    10981 ttcactattt aattcagcta ccgcagaaaa ctctatgttt ttaacaaaaa tagcaccata
    11041 cttacaagta ggttttatgc cagaagctcg ctccacaata agtttaagtg gtccaggagc
    11101 ttatgcatca gcttactatg atttcataaa tttacaagaa aatactatag aaaaaacttt
    11161 aaaagcatca gatttaatag aatttaaatt cccagaaaat aatctatctc aattgacaga
    11221 acaagaaata aatagtctat ggagctttga tcaagcaagt gcaaaatatc aatttgagaa
    11281 atatgtaaga gattatactg gtggatctct ttctgaagac aatggggtag actttaataa
    11341 aaatactgcc ctcgacaaaa actatttatt aaataataaa attccatcaa acaatgtaga
    11401 agaagctgga agtaaaaatt atgttcatta tatcatacag ttacaaggag atgatataag
    11461 ttatgaagca acatgcaatt tattttctaa aaatcctaaa aatagtatta ttatacaacg
    11521 aaatatgaat gaaagtgcaa aaagttactt tttaagtgat gatggagaat ctattttaga
    11581 attaaataaa tataggatac ctgaaagatt aaaaaataag gaaaaagtaa aagtaacctt
    11641 tattggacat ggtaaagatg aattcaacac aagcgaattt gctagattaa gtgtagattc
    11701 actttccaat gagataagtt catttttaga taccataaaa ttagatatat cacctaaaaa
    11761 tgtagaagta aacttgcttg gatgtaatat gtttagttat gattttaatg ttgaagaaac
    11821 ttatcctggt aagttactat taagtattat ggacaaaatt acttccactt tacctgatgt
    11881 aaataaagat tctattacta taggagcaaa tcaatatgaa gtaagaatta atagtgaggg
    11941 aagaaaagaa cttctagctc actcaggtaa atggataaat aaagaggaag ctattatgag
    12001 cgatttatct agtaaagaat acattttttt tgattccata gataataagc taaaagcaaa
    12061 gtccaagaat attccaggtt tagcgtcaat atcagaagat ataaaaacat tattacttga
    12121 tgcgagtgtt agtcctgata caaaatttat tttaaataat cttaagctta atattgaatc
    12181 ttctattggt gattacattt attatgaaaa attagaacct gttaaaaata taatccacaa
    12241 ttctatagat gatttaatag atgagttcaa tctacttgaa aatgtatctg atgaattata
    12301 tgaattaaaa aaattaaata atctagatga gaagtattta atatcttttg aagatatctc
    12361 aaaaaataat tcaacttatt ctgtaagatt tattaacaaa agtaatggtg aatcagttta
    12421 tgtagagaca gaaaaagaaa ttttttcaaa atatagcgaa catattacaa aagaaataag
    12481 tactataaag aatagtataa ttacagatgt taatggtaat ttattggata atatacagtt
    12541 agatcatact tctcaagtta atacattaaa cgcagcattc tttattcaat cattaataga
    12601 ttatagtagc aataaagatg tactgaatga tttaagtacc tcagttaagg ttcaacttta
    12661 tgctcaacta tttagtacag gtttaaatac tatatatgac tctatccaat tagtaaattt
    12721 aatatcaaat gcagtaaatg atactataaa tgtactacct acaataacag aggggatacc
    12781 tattgtatct actatattag acggaataaa cttaggtgca gcaattaagg aattactaga
    12841 cgaacatgac ccattactaa aaaaagaact agaagctaag gtgggtgttt tagcaataaa
    12901 tatgtcatta tctatagctg caacggtagc ttcaattgtt ggaataggtg ctgaagttac
    12961 tattttctta ttacctatag ctggtatatc tgcaggaata ccttcattag ttaataatga
    13021 attaatattg catgataagg caacttcagt ggtaaactat tttaatcatt tgtctgaatc
    13081 taaaaaatat ggccctctta aaatagaaga tgataaaatt ttagttccta ttgatgattt
    13141 agtaatatca gaaatagatt ttaataataa ttcgataaaa ctaggaacat gtaatatatt
    13201 agcaatggag gggggatcag gacacacagt gactggtaat atagatcact ttttctcatc
    13261 tccatatata agctctcata ttccttcatt atcagtttat tctgcaatag gtataaaaac
    13321 agaaaatcta gatttttcaa aaaaaataat gatgttacca aatgctcctt caagagtatt
    13381 ttggtgggaa actggagcag ttccaggttt aagatcatta gaaaatgatg gaactaaatt
    13441 acttgattca ataagagatt tatatccagg caaattttac tggagattct atgccttttt
    13501 cgattatgca ataactacat taaaaccagt gtatgaagac actaatatta aaattaaact
    13561 agataaagat actagaaact ttataatgcc aactataact actgacgaaa ttagaaacaa
    13621 attatcttat tcatttgatg gagcaggagg aacttactct ttattattat cttcatatcc
    13681 aatatcaatg aatataaatt tatctaaaga tgatttatgg atatttaata ttgataatga
    13741 agtaagagaa atatctatag aaaatggtac tattaaaaaa ggaaatttaa tagaagatgt
    13801 tttaagtaaa attgatataa ataaaaataa acttattata ggcaatcaaa caatagattt
    13861 ttcaggcgat atagataata aagatagata tatattcttg acttgtgagt tagatgataa
    13921 aattagctta ataatagaaa taaatcttgt tgcaaaatct tatagtttgt tattgtctgg
    13981 ggataaaaat tatttgatat ccaatttatc taatactatt gagaaaatca atactttagg
    14041 cctagatagt aaaaatatag cgtacaatta cactgatgaa tctaataata aatattttgg
    14101 agctatatct aaaacaagtc aaaaaagcat aatacattat aaaaaagaca gtaaaaatat
    14161 attagaattt tataatggca gtacattaga atttaacagt aaagatttta ttgctgaaga
    14221 tataaatgta tttatgaaag atgatattaa tactataaca ggaaaatact atgttgataa
    14281 taatactgat aaaagtatag atttctctat ttctttagtt agtaaaaatc aagtaaaagt
    14341 aaatggatta tatttaaatg aatccgtata ctcatcttac cttgattttg tgaaaaattc
    14401 agatggacac cataatactt ctaattttat gaatttattt ttgaacaata taagtttctg
    14461 gaaattgttt gggtttgaaa atataaattt tgtaatcgat aaatacttta cccttgttgg
    14521 taaaactaat cttggatatg tagaatttat ttgtgacaat aataaaaata tagatatata
    14581 ttttggtgaa tggaaaacat cgtcatctaa aagcactata tttagcggaa atggtagaaa
    14641 tgttgtagta gagcctatat ataatcctga tacgggtgaa gatatatcta cttcactaga
    14701 tttttcctat gaacctctct atggaataga tagatatatc aataaagtat tgatagcacc
    14761 tgatttatat acaagtttaa taaatattaa taccaattat tattcaaatg agtactaccc
    14821 tgagattata gttcttaacc caaatacatt ccacaaaaaa gtaaatataa atttagatag
    14881 ttcttctttt gagtataaat ggtctacaga aggaagtgac tttattttag ttagatactt
    14941 agaagaaagt aataaaaaaa tattacaaaa aataagaatc aaaggtatct tatctaatac
    15001 tcaatcattt aataaaatga gtatagattt taaagatatt aaaaaactat cattaggata
    15061 tataatgagt aattttaaat catttaattc tgaaaatgaa ttagatagag atcatttagg
    15121 atttaaaata atagataata aaacttatta ctatgatgaa gatagtaaat tagttaaagg
    15181 attaatcaat ataaataatt cattattcta ttttgatcct atagaatcta acttagtaac
    15241 tggatggcaa actatcaatg gtaaaaaata ttattttgat ataaatactg gagcagcttc
    15301 aactagttat aaaattatta atggtaaaca cttttatttt aataataatg gtgtgatgca
    15361 gttaggagta tttaaaggac ctgatggatt tgagtatttt gcacctgcca atactcagaa
    15421 taataacata gaaggtcagg ctatagttta tcaaagtaaa ttcttaactt tgaatggcaa
    15481 aaaatattat tttgataatg actcaaaagc agtcactgga tggaggatta ttaacaatga
    15541 gaaatattac tttaatccta ataatgctat tgctgcagtc ggattgcaag taattgacaa
    15601 taataagtat tatttcaatc ctgacactgc tatcatctca aaaggttggc agactgttaa
    15661 tggtagtaga tactactttg atactgatac cgctattgcc tttaatggtt ataaaactat
    15721 tgatggtaaa cacttttatt ttgatagtga ttgtgtagtg aaaataggtg tgtttagtgg
    15781 ctctaatgga tttgaatatt tcgcacctgc taatacttat aataataaca tagaaggtca
    15841 ggctatagtt tatcaaagta aattcttaac tttgaatggt aaaaaatatt actttgataa
    15901 taactcaaaa gcagttaccg gatggcaaac tattgatagt aaaaaatatt actttaatac
    15961 taacactgct gaagcagcta ctggatggca aactattgat ggtaaaaagt attactttaa
    16021 tactaacact gctgaagcag ctactggatg gcaaactatt gatggtaaaa aatattactt
    16081 taatactaac acttctatag cttcaactgg ttatacaatt attaatggta aacattttta
    16141 ttttaatact gatggtatta tgcagatagg agtgtttaaa ggacctaatg gatttgaata
    16201 ttttgcacct gctaatacgg atgctaacaa catagaaggt caagctatac tttaccaaaa
    16261 taaattctta actttgaatg gtaaaaaata ttactttggt agtgactcaa aagcaattac
    16321 tggatggcaa accattgatg gtaaaaaata ttactttaat cctaataatg ctattgctgc
    16381 gactcatcta tgcactataa ataacgacaa gtattacttt agttatgatg gaattcttca
    16441 aaatggatat attactattg aaagaaataa tttctatttt gatgctaata atgaatctaa
    16501 aatggtaaca ggagtattta aaggacctaa tggatttgag tattttgcac ctgctaatac
    16561 tcataataat aacatagaag gtcaggctat agtttaccag aataaattct taactttgaa
    16621 tggcaaaaaa tattattttg ataatgactc aaaagcagtt actggatggc aaactattga
    16681 tagtaaaaaa tattacttta atcttaacac tgctgttgca gttactggat ggcaaactat
    16741 tgatggtgaa aaatattact ttaatcttaa cactgctgaa gcagctactg gatggcaaac
    16801 tattgatggt aaaagatact actttaatac taacacttat atagcttcaa ctggttatac
    16861 gattattaat ggtaaacatt tttattttaa tactgatggt attatgcaga taggagtgtt
    16921 taaaggacct gatggatttg aatactttgc acctgctaat actcataata ataacataga
    16981 aggtcaagct atactttacc aaaataaatt cttaactttg aatggtaaaa aatattactt
    17041 tggtagtgac tcaaaagcag ttaccggatt gcgaactatt gatggtaaaa aatattactt
    17101 taatactaac actgctgttg cagttactgg atggcaaact attaatggta aaaaatacta
    17161 ctttaatact aacacttata tagcttcaac tggttataca attattagtg gtaaacattt
    17221 ttattttaat actgatggta ttatgcagat aggagtgttt aaaggacctg atggatttga
    17281 atactttgca cctgctaata cggatgctaa caacatagaa ggtcaagcta tacgttatca
    17341 aaatagattc ctatatttac atgacaatat atattacttt ggcaatgatt caaaagcggc
    17401 tactggttgg gcaactattg atggtaatag atattacttc gagcctaata cagctatggg
    17461 tgcgaatggt tataaaacta ttgataataa aaatttttac tttagaaatg gtttacctca
    17521 gataggagtg tttaaaggac ctaatggatt tgaatacttt gcacctgcta atacggatgc
    17581 taacaatata gatggtcaag ctatacgtta tcaaaataga ttcctacatt tacttggaaa
    17641 aatatattac tttggtaata actcaaaagc agttactgga tggcaaacta ttaatggtaa
    17701 agtatattac tttatgcctg atactgctat ggctgcagct ggtggacttt tcgagattga
    17761 tggtgttata tatttctttg gtgttgatgg agtaaaagcc cctgggatat atggctaaaa
    17821 tatatgtttg ataaaaaatt attcctgtgc tactcagaaa ttatttttat ataataaata
    17881 ttgagattta attaaaagtc atgtgttatt gtaatacatg acttttagtt aaaatttttc
    17941 tatcatttaa taatctatta ttcttgacta ttttataata aaattcatat atggaaatat
    18001 taatactaaa taattaatag ttgatagaaa atagataata tgctaaaagc aaaaactaat
    18061 ttagagcctt gtaactgttt atttgcaatt ataaaaacat ctttaaacat attgactata
    18121 atataaaata ttaactataa tacaaaacaa tattaattta ttttctctac agctatccct
    18181 ggtatagtta tatttccacc catagttgat tcataagtta tagttccagc acttatacct
    18241 cttatagtta tgtaatcatc ctctaacact cttgaaggag ttattgattt tttataacta
    18301 catagtacga ccttatcata atttccagac acagctaatc ttatttgcac ctcatcacca
    18361 tcttcaataa cttgaataac cttaccttca aattttacct ttttgtactt ataatcatca
    18421 ggtgttctag ctaattggtc ataagtaata ccagtatcat atcctttctt ctcttcttct
    18481 tcttttttac gttgttcttc agccttttta gcttcttcag cttttttagc ttcttcagct
    18541 ttacgttgat tttcagcttc aatagctttc ttttcgtcgt ctttcatttt gaaccatggt
    18601 tcagcatcag acaatttgct atttaaagtt tctatttctg ttttttgaga atctataact
    18661 gatgtttgat tagaaatgac ctcctcatgg tcttcagaac aagctggtga ggatatattg
    18721 ccaaaaaaca caccaaaata aatgccagta gagcaatatc ctttgtgctc ttaaagaatt
    18781 taattatttt cttagagctt ccttttcttt cattactaaa ttcgttaccc tcattttttt
    18841 tagaaaacat aatacaatct cccttttatt agatatattt tattttaaaa tttaaaaact
    18901 taaaataact agttgactaa aaattatata ttcatatttt cctaaaatat atttccccta
    18961 agcataattt tacaaaataa atcaagaaga ttcaatatat tttgaaaaat gaggtaaaaa
    19021 tgtcagatta taatataatt ttcttgaagg tgaattttat atattaaatg aaacataaag
    19081 tattttattt gtataaaact atattatgat gtaattaaat gattcagtac tttagaggtg
    19141 gtaaaatata gatagatgaa agagcataaa taaagtgata taataaaaaa ttaaatatta
    19201 actataataa aaaaatatct ggtactaagt ataatacaaa aataatatat cagaaagaag
    19261 gtgaagtatg ggagaactac aaaaaattcc aggggtaggg aaagcaacag aaaaatcttt
    19321 aatcatgtta ggatatacaa ctattaaatc acttaaagat gcaaacccag cacaaatgta
    19381 tgaaaaggaa tgtttaatgc gtggacagca catagacaga tgtcagttat atgtatacag
    19441 atgtgcagta tattttgcat caactgaaaa tccagaacca gaaaaattaa agtggtggta
    19501 ttggaaagat taaaaaatca aaaaagttag atataaaaaa gagttgaata tccgtttaaa
    19561 taataaaaac taatactcaa ctctttttta gtcgtaaatt ttatgtaaat ctatttgtat
    19621 ggctaaatat acccatcaat aaatgtataa atataccaat caataaatga ctaaacatac
    19681 tacctaacaa aggattaaat aaattactta acaaagcatt ctaaaacaat taattagaaa
    19741 ctgtttcttc aagccatttt ctacattgcc caatatttac catagggtca aagccttggt
    19801 cttttccctt atttaaaagc atatcacaag ggaaagtatc acattcacca caatgattaa
    19861 gttccttact ttcacagcaa gttttaacct tacattctcc accccaaaat ggtttttcca
    19921 tagttgggca accagtgcaa tttacttgtt ctttttttgt acaactgtca caacagacac
    19981 cacatcttga ttcaaacatg ttcaaacatc ctttccatta tttaaaaata ttataaaatg
    20041 attttagatg actacaaaag tgcaaatagt tgattttaag tcatctaaat gttaaacata
    20101 aaattattaa tactggtaaa tttataaaaa ctattccaaa aatatttttg aatatttcaa
    20161 aacacaataa attacttcaa atccctttga atattccata acactataga ttactttaaa
    20221 tccccttgaa tatatttcac agcattatag attgctttaa atctctttga atattctaca
    20281 agactataga ttagtttaaa ttcctttgaa tatttcataa cactatagat tagtttaaat
    20341 ctctttgaat attctacaag actatagatt agtttaaatt cctttgaata tttcataaca
    20401 tcataaatta ctttaaatct ctttgaatat tctacaagac tatagattag tttaaatccc
    20461 tttgaatatt tcataacact atagattact ttaaatttct ttgaatattc tacaagacta
    20521 tagattagtt taaatccctt tgaatatttc ataacaccat agattacttt aaatcccttt
    20581 gaatattcta taacactata aattactttt aacttttata taaccataaa gtttttatct
    20641 ggcactttaa atggagtttt tatatcaaat ttgccttcca tcgaataacc aaacttaatt
    20701 taattacaca ttccaagagt caaatattca ttcaatatat ttgataattc tatgttatag
    20761 ccataattaa atatagatta ttaaagttaa atatttattt aatgtattga atgatttttt
    20821 agctatattt aattaagttt cattatataa tataaaaatt gtttttgcat taagttttaa
    20881 tataacacat aataatttta aataataaca ttattatata tttttttatt ttaggagtat
    20941 atctattata tagtgagtag ataaaacata taaaattcaa ataaaagata tatattttta
    21001 aataaaaggg atataaattt caaaccaaaa agaatataaa tttcaaacca aaaaatatct
    21061 agcatttacc attaagaaat aacatcattc tttctaaaat ttctattggc aatttcagaa
    21121 aatactatag tagtaataaa tgcaacacat attgtaacta tagtgtcatt aacatttaaa
    21181 gcagattgct ttataacccc catagcacta cctaacatag aataagggaa aaatatacca
    21241 acagcaggtt ttgctactat taatcccata ccaaatagag aaaggcaaag actaatacca
    21301 ataggagttg caaaacttct aatctttata gacatgtata attgtataga agctattgaa
    21361 atagaaataa tccaaccttt agcaatccaa ccagtcaatt ctttaggtac actaccagaa
    21421 aaaccaaaca tatttcctgc aactatataa aagataacaa agaaaacttg tgtaatagct
    21481 gtaagtattg aaactactgt aagtttagat aaaaagatat tttttaaatt aactggcagt
    21541 gtcattacat tattccaatt atgattcata tgttcaagcc tacaaatata tgcacaaaag
    21601 attgcgatta agataggaaa gaaaaattcc ccataaaaaa gactaacttg agtccataag
    21661 ctgtaccatt cttttttgag tatgccttga tttagataaa aattaccaga accaatcaac
    21721 acacttataa gtggcaaagc taataataca taccatataa aagaattttt taactttaga
    21781 atttctccca aaactgactt ccttaacatt taaatccctc ctatacttct ttttttaata
    21841 aatgatttct tccaatataa taaattagca ttccaattaa gaaaactaaa atcgtaatag
    21901 aaaaattcat atcaattcta tagacagatg aacctaaaac attatcataa gcataactta
    21961 aaggtgataa ctctaggtaa taagaccata taaacaatct acgaatacct tgataaaaca
    22021 aacctgatgt caaacctata aaactaccaa tcatgccaaa tgtaattgca atcatttgat
    22081 ttggaattac agttgcaatc cataggtgta gtgcaatgat agcaatactt acaagaattg
    22141 ttcctaatgt gtattttaaa agtaaagata cagaaattga ctcaataacc cctctaaaat
    22201 gtccaaacaa cacaatagat aacacttgca tcaatacagg tacagatacc aaaatagcag
    22261 aacataaaaa tttggataaa taaatactat ttaaagatgt cacagaagat tttaaaagct
    22321 tccatgtatc tcctttatgt tctatatcgc ttatacgtga tgtaattatt gatattaaga
    22381 taggaaagaa tagaccattt aaacttgcaa aactcataag catataggaa tattcaaatc
    22441 cacctaacat atctggatta cgtgtaatag ccctatttga atttacgata caccacatta
    22501 tttcaacagc tacaaataaa aaggtcatca gaataatctt ctttctttta agtttataaa
    22561 attctagacc aaggtatttc attataaagt caccgcctta ccagtaagtt ctaggaatat
    22621 atcttccaag ctttttttat gttcttctat tctaaataca tctatatttg aatggacaag
    22681 cataccattt attttagcca catctgagtc ttttaaattt tcaatagtca agtacccatt
    22741 ttgtataagt gacatatatc ctttagtatt taatagcttt tgtgcagata caacattctt
    22801 agctttgata gcaatctgac tttgacctct attatgaagt tcttttatgc tatcttgaaa
    22861 aaccagttcg ccatgattta ttattcctat tgatgtggca atttggtcaa tttcacttaa
    22921 aagatggcta gagattagaa cagtcatgcc gtatttttct ggtagagatt ttattaattc
    22981 tctaatttcc tcaatccctg ctgggtcgag tccatttgta ggttcatcaa gtattaataa
    23041 tttgggaaac ttcattattg ccatagcaat gccaagacgt tgcttcatac ctaaagaata
    23101 ttgactaact tttttatttt tttgattttc taaccttaca atttttaatg cttcatttac
    23161 atttttttta ggtaaatcta agagtctttg cattatggtc atgttttcaa gccctgtaag
    23221 atgaccatag tatgatggag attctatcaa agaacctata tcttttaaaa ttgatattct
    23281 atttttttca tttaactctt tacctaaaat attaatattt ccttgtgtgg gtttagcaag
    23341 tccaagaagc attttaagag tggtagattt tccagctcca ttaggaccca aaaaaccata
    23401 tacagctcct tgtggaactc ttaggtctat atcctttact ctaaatattt tattgtattc
    23461 ctttgaaagt ctttgtgttc taattatcat ttccatatgt ttcatcccct tttttaatct
    23521 gtgcttattg attcttttaa cttatatcag tataataact tggttacatt tcagttagct
    23581 gaagtttacc ttacaataac cttaaaagtc tatttaggca aagttgtgaa aatgggtata
    23641 tggtatacta aaggagggtg atgattatgg agtcaataaa agataaaaaa atacttgtgg
    23701 ttgatgacca caaggaatta ttaaaaatga tagatgaaat cctaagaaaa gagggattta
    23761 gtagagtatt tttagcatca agttatgaag aagctgttag ggtatttaga aatgtaaagc
    23821 cagattgtgc aattttagat gttgtattgc cagatggaga tggtttctct attatgagaa
    23881 aaattagaga gacatctaag ataccagtta tttttctctc tgcaagaggt gaagatgaag
    23941 atagattgat tggtttggga ttaggggctg acgattatat agtaaagcca tttttaccaa
    24001 aggaacttac tttaaggctt gtgggtatat taaatcgtgt atatgtgcct atagaagaag
    24061 aggagttgcc agtatttaaa ctgggagatt ctgttgttgt gaatttaaat agtgcatgtg
    24121 ttgagaaaga tgggcaagag atttctttaa cagctaaaga gcattcgttg cttttaaagt
    24181 tgtatgaaaa taaagggaga attgttacta atgattcact atgtcaagcc atttggggag
    24241 atgatatgta tggatatgaa aataccctta tggttcatgt tagaagggtt agagagaaga
    24301 tagaaaaaac tccatctaca cctaaacatc ttattacagt aagaggtctt ggatataagt
    24361 tgatgattaa ttaattttag atattagaat aaaagaaatc aagaggagtg atttaatttt
    24421 ggatagtgta aagtacatat tgaggcgatt tataggttca agtatcttga tttcattact
    24481 ttttattgta ttaaatatag caggttttct tctgttttca tatatgctat ttgtatctaa
    24541 atattctgat aatttagata caagtgatag cagagaaata aaatcaaact tgattatgat
    24601 tgaagataat ttgattttaa aagatggaaa gtttatttta gatgattcta gtaaggaagt
    24661 actacataaa aataaagttt gggcaatgtt aattgataac aatggagata gaatatgggg
    24721 atttgattta ccaaaagaaa ttccaagtca ttatactttg acagatgtag caaagttttc
    24781 aaggttcttt ttaaaggact atcctgtgta tgtatgggaa catccaaatg gaatattagt
    24841 aacaggttat ccaaaggaca aatacactaa atttaacctt acttatacga ttaaggaaat
    24901 agaacaattt cctatgttaa taataggtat gtttctggtt aatgcaatag ttactttttt
    24961 aatagctcta ttcataggtt taaaaatggt gaaatctata aaaccaatta ttactggcat
    25021 aaagcttatg tcaaaaggag aaccagtact tttacaagaa aaaggaatac taagtgatat
    25081 ttcaaaatct attaatactg tatctaaaga gttgcaaatg aaagatgaaa aacttaggaa
    25141 gaaagaggaa gctaggtcta actggattgc aggaatatct catgatataa gaactccact
    25201 ttcaatgata attggatatg ctggagaact tgaagaaagc agtagccttt caaatagaga
    25261 acaagagcaa gtgtctatta tatgcaatca aggggttaaa atcagagaat tagtaaatga
    25321 cctaaattta gtatctaaac ttgaatataa tatgcaagca ttgaattgtg ataagattag
    25381 agtttctgcg tttttgagag agcttatttc tgagtttata aataataatt tggataatga
    25441 cttttatgtt gaacttgata tactaaatga agatattatt atagatgcag ataaaaaatt
    25501 attaaaaagg gctattagta atttaataca aaatagtata actcataacc aacaaggatg
    25561 taatataagg gttacctcta agtctgattt agatttttgc tatataattg ttgaagatga
    25621 tggaaaaggt atgagtcaag aaaaaattaa tagtttatta aagagccaaa atggactaag
    25681 tgaggcatat gccaaaggtc aaaatcatgg tctaggtatt ttgatagtag ctggaattat
    25741 taatgcacat agaggtaaat tagatattat gagtattgat agtcagggac taaaaacaat
    25801 actaaaatta cctctaatta agtgatattt tataaaataa taacagataa gaatgaagaa
    25861 tgaaaatatt ttgaaaataa ttttattctt tattgacaaa ataactctat tagagtagaa
    25921 taaggataaa ttcttttctt gtcaagtttt attaaagtaa agagtaactt gtgctttatg
    25981 cgcttatggc tgagttactc atggtatcaa aattttcata gaaataatat tttggaatta
    26041 ttgtaaggtt attaaattct ttagataatt ccattttttt tattttttag ttaatattta
    26101 attttattat tgacaaaaaa attctactaa aatagaatta tggtatagtg ttttttaatt
    26161 ttaagaaaaa atataatgac atcctaaaaa agttttaatt atacgttgtt ctgtgtagtt
    26221 ataatagctt ctatgtaact attgtaagta tattttatta taattattta tttaaagtac
    26281 gataaatgtt ttaaattgaa gtattttgca ccattgagtt ctactaaagt agagtttttg
    26341 tgtagtattt ttagaaataa catatatata tatgtattta tgttgaaata tatgggaaat
    26401 ttataatata attaatgaaa aaatttaaac tttgtaatat ataaataaaa aaactctaaa
    26461 atagaaggat ataattatat agaatgtttc aattaaacaa ggcaaaaact ataatcttaa
    26521 aattaaaatt aaaattaaca ttattcttaa gaagtaagaa atttaagaag taaaaagttt
    26581 agtaataagt catagcaagt aagaaattta ggaagtggga agtttagtaa taatttatag
    26641 taagtaagaa atttaggaag tgggaagttt agtgataagt agtagcaagt aagaaattta
    26701 ggaagtagga agtttagtaa taatttgtag caagtaagaa atttagggag taggaagttt
    26761 agtagtaata atttatagta agtaagaaat ttaggaagtg ggaagtttag taataatttg
    26821 tagcaagtaa gaaatttagg aagtaggaag tttagtaata atttgtagca agtaagaaat
    26881 ttagggagta ggaagtttag tagtaataat ttgtagcaag taagaaattt agggagtagg
    26941 aagtttagta ataatttgta gtaagtaaga aatttagaaa gtaggaaatt tagtaataat
    27001 ttatagtaag taagaaattt agaaagtagg aagtttagta ataatttata gcaagtaaga
    27061 aatttagaaa gtagaaagtt tagtagtaat ttatagtaag taagaaattt agtaagtgag
    27121 aagtttagtt ataatttata gtaagtaaga aatttaggaa gtgagaagtt cagtaataag
    27181 ttgtagtaaa taaaaagttt aggaagtagg aagtacagta ataagttgta gtaaataaaa
    27241 aatttaggaa gtaggattta ctgaaataca aatatttaaa atcaaagagt ttaaaagaaa
    27301 ggagagctac tggacaagta tccaaaatag atagctgagt acaaaatatc tcataaaatt
    27361 aagcaatata atacaagaga attttgacat tatttatata tatttaccgt gtacaaatag
    27421 ctaaatttag gattaagatt gaaaaatatc ttataagtct gagcttatat aaatccgtat
    27481 aagatgtatt taatcgaaaa attttattat ggatattgct tgtctatatt ctgagtagca
    27541 aggttttatc atgactataa aaaagttgcc acaatcagaa ttaaagataa tgaaatttat
    27601 atggaaatca gattccaaag taacatctag agatattgtt ttaggaatgg agcaaaaata
    27661 tcaatggaaa caaacgacaa ctttgactct tttatctaga ttagtagtaa aaagatttct
    27721 aaattctcaa aagatagata aatatacaca ttatgaagtt ttaattaaag aaaaggaata
    27781 cataggagtt gagacaagag atttttttag aaatattcat gattcttcta taaaaagttt
    27841 attgttgtca ttacatgaaa atattaattt gagcaaagat gatattttac ttattgaaga
    27901 gtggataaaa aatctaaaag aagaggagaa agacgtataa gcaaacgtat ttcttatagc
    27961 attaatataa agtgtatgta agtgtattta tgtaatatat tagtctactt aagtaatatg
    28021 acaaatgatt ataagtggat tatgatacta taatgttaat ctaaataaat taaatataaa
    28081 ttgatagtgg atattctatt taattaaatt taaaaagcta ccttttctta taagtataat
    28141 taaggtagct ttttaaatag aggtagtgtg attaaagaga atttttaaat ataaattgtg
    28201 aagctttaat atagatgata atatatattt tgcaaatatg acacagtgtt ttcgtattta
    28261 agatgataaa ataaatagga attaatgaag atattgaaaa aataaaaata aaggattaat
    28321 ataagatatt aaagagatag agataaaagt gttaatagaa gatattgaaa aagtaaaaat
    28381 aaaggattaa tataagatac tgaagaggta gaaacaaaag tattaataga agatattgaa
    28441 aaaataaaaa caaaagatta ataaaaggta ctgaatagat agagataaaa gtgttaatag
    28501 aagatattga aaaaataaaa gattgatata agatactaag gaggtagaaa caaaagtgtt
    28561 aatagaagat actaaaaaag taaaaataaa ggactaataa aaggtactga agagatagag
    28621 aaaaaaatgt taatagaaga tactgaaaaa atagaaataa aaaattagga ggaaaattta
    28681 tgaaatatca ggtttcatta ttagcagtga aggatattga agtatcaaaa aaattttaca
    28741 aagaattatt tgagcaagaa attgaattgg acttaggtaa aaatgtaaca tttaaaggag
    28801 gatttgctat acaagaagac ttcgcatggc ttacagggat taatccagat acaattatac
    28861 aaaaatcaaa taatatggaa ctttattttg aagttgatga ttttgacgaa tttattgaaa
    28921 aactcaatta ttataaagat gtagagtttg tccataagcc actaaaacat gaatggcaac
    28981 aaagagtagt gcgtatttat gacccagata agcatattat tgagatagga gagtctatgg
    29041 aagttatagc tagaagatat ttatctgagg gatattctgt agaagaaact tctaaaataa
    29101 ttcaacatcc aattgaattt gtaaagcagt gtgaaaatag taaggaatga ttgtttaaat
    29161 tataattatt tagtagaaat taattgtagt agaactaatt caagataata tataggacta
    29221 gtatttgaca aatgtcataa atta
//
LOCUS       DACTZW010000047        28780 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.047, whole genome shotgun sequence.
ACCESSION   DACTZW010000047 DACTZW010000000
VERSION     DACTZW010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28780)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28780)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28780
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.047"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            268..1698
                     /locus_tag="JAM15_11205"
     CDS             268..1698
                     /locus_tag="JAM15_11205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HAT6798819.1"
                     /translation="MDIKNKIKSIFLPEKNDYLDDEEFEYDIENNEEDLKEDNKVHLN
                     DLSRVKYDYRELKDIENQTEEMCLLAVKQDGTIIEFVKDKTYKVCMEAVKQTYKALKY
                     ITNQNEDICIEAVKQNYRALYYINNKTENVLIEAIKNASTYDVMEVFKFVEDQTEDVC
                     LAFIERASKNDVAEILKGIKEQTPAICLEAVKKDGKSLAYVKEQSNSICLEAVKENYS
                     ALSCVKEQTEEICIEAVKQNDFALYYVNEQTEKICMEAVKRSYMALQYVNKQTEEICM
                     EAVRIDGRALQYVKEQTEEICLESVRQNGKVLQYVKKQTENICIEAVRGSFEELEIKE
                     ILSYVKIPTERIFVEAVKQNGKILKYVENQTELICLEAVRENYNALAYVKEQTEEICL
                     EAVNQSYEALKYVKEQTEEVCLKAVKQDYRMLKYVNNQTEKICLEAVKQNYRALEFVD
                     NQTEKVCLEAVKQNRKALQYVKQKQS"
     gene            2066..2644
                     /locus_tag="JAM15_11210"
     CDS             2066..2644
                     /locus_tag="JAM15_11210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HAT6798820.1"
                     /translation="MFKRYAEKMTSVLICNNMIDNNESKVYSYGFEILIAFIVNITTM
                     LFIGFLFGKFTYVLFFLMCYCPIRQFSGGYHADNYFRCLLTFIFIILSTILIIENINI
                     DLFKNIIMIIASVSWVGICVLCPIEHRSNPISDREKFVYKKTAIFISTVVLLITILSF
                     SLSIFVDYFTYSVFAMFWIFVMLVLGKLKAKV"
     gene            2674..2820
                     /locus_tag="JAM15_11215"
     CDS             2674..2820
                     /locus_tag="JAM15_11215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HAT6798821.1"
                     /translation="MKKFIVRFMKFASSLALSTAILSANSTCPWIIHQPKVPKEISNL
                     KKTN"
     gene            3125..4504
                     /gene="scfB"
                     /locus_tag="JAM15_11220"
     CDS             3125..4504
                     /gene="scfB"
                     /locus_tag="JAM15_11220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioether cross-link-forming SCIFF peptide
                     maturase"
                     /protein_id="HAT6798822.1"
                     /translation="MSMIHKFSMNGYNIVLDVNGGAVHVLDDVAYDLLDFYKEKSKEE
                     ILEILKSKYQEEKINEAYEEILNLEKEGLLYTEDTYQYHPSFVHREPVVKALCLNVAH
                     DCNLKCKYCFAAQGDFGGEKELMSFEVGKAAIDYLIANSGSRKNLEIDFFGGEPLMNF
                     EVVKQLVDYGRSVEKDYNKNIRFTITTNGVLLNDEIIDYINENMHNVVLSLDGRKEVN
                     DNMRPTLNDKGSYDITLPRFKKLVEKRAKDKYYYIRGTFTRDNLDFSKDVMHFADLGF
                     KLTSVEPVVGDESNPYALREEDLPKIFEEYEKFAVEYADRQLQEDGFKFFHFMIDLNQ
                     GPCVIKRITGCGAGNEYLSVTPNGDIYPCHQFVGNEEFKMANIFDEEIVLPENLKNMF
                     REAHVYTKEECKQCWNKFYCSGGCHANAINFNNDISKPYELGCEMQRKRTECSIMIQA
                     KLMLEGATN"
     gene            4533..5030
                     /locus_tag="JAM15_11225"
     CDS             4533..5030
                     /locus_tag="JAM15_11225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HAT6798823.1"
                     /translation="MIRDYLEDKPLIDESVFVAKSADVIGNVKIGKDSSIWYNAVVRG
                     DEEPITIGENTNIQDCSIVHGDTETIIGNNVTVGHRSIVHGCKISDNVLIGMGSIILD
                     NAEIGEYTLIGAGTLITSNKKFPPGVLIMGSPGKVVRELTEEDKKYIDESYEWYLEAA
                     QNQKY"
     gene            5328..6992
                     /locus_tag="JAM15_11230"
     CDS             5328..6992
                     /locus_tag="JAM15_11230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HAT6798824.1"
                     /translation="MRISYRNLKRYREIGYILIKYGFSFIVERLNIEGIAYKIPLFDP
                     PEEIKNMTTGERMKRVLEELGPTYIKIGQILSTRKDLLDQDIIDEISKLRDDVEKFDS
                     NIAIDIFKEEVGLSIEEIFLEFKEEPIAAASIGQVYEGVLKTGEEVIVKIQRPNIEKI
                     IKSDLEILRTIANTLKDLKKDFNLDLVQMIEEFQTQLMRELDYTFEAINATKFSRIFK
                     NSDEVYIPKVYSEYNTKKILVMEKVNGTKLSDVEKIRRLGYNTKTIVEIGVRSFFTQV
                     LSHGFFHADPHPGNIFVVAKNKIAYIDFGMIGIIDNKTLNQLNEIALAGVEKNVDKII
                     YLLIEMDALNGEADIKGLRQDLLYLIHYYYDISIEKINVTDILNELFRFFRQYKIVMP
                     AQFVTLAKTVITLEGTSRTLNTDFSFGSMGKEFMKHHYKSKFNPKNVVLSSRQNVEEI
                     LLDIKTIPKQLKAILKNIERNNIKMQIEDVKMTRLENCIIELTSQISLSLVLASIIVG
                     SSLIIASPNIENNIWIKFTAIAGFFISFIIGLCLVIRSIRSKYKKD"
     gene            7005..9455
                     /gene="recJ"
                     /locus_tag="JAM15_11235"
     CDS             7005..9455
                     /gene="recJ"
                     /locus_tag="JAM15_11235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HAT6798825.1"
                     /translation="MKKWILKYKGKIEESEFSKKLNISPEICQILKNRGICTEKDSEI
                     FMNPSLDYLRDPFLMKDMQKAVDRIKLAVEKNEKIWIYGDYDVDGVSSTSILCLYFKS
                     IGYNVDYYIPNRLEEGYGINEDAIKLISSRGCDLIISVDCGITSVSEVNTANDLGIDV
                     IITDHHECQSEIPSAFAVINPKQEDCNYPFDSLCGCGVAFKMIQALTPKEEFKTSMYN
                     YLEIVTLATICDIVPLIDENRIIVKNGLKSMKEGKNIGLRELIKVCGVESDKIGSSHI
                     GFAIGPRINASGRLGYSYLGVELFTTQSQEEAVEIASILEEKNNERQMIEAKMYHEAE
                     KMLKSNSRYNDDKVLVLAKEGWQHGIIGIVASKLTEKYYKPTILLGIENGEATGSARS
                     IKGFNIFEALIKCKDLMTKFGGHEQAAGLSLDSDNVEILANEINKFADYNLTEDDMIE
                     NVNVEFELQENVINLNLVEELHKLEPFGLNNPNPRFIVRNYILKDLKVIGKNQQHLKL
                     SIEKEKSYECIGFNMSHLKSMYKVGDKVDVLFQLDENNYMGNRKVQFLLKDIRLARPK
                     SASNDKLSLKLMSKIIPKDTQSLYNISVSDFELFDGNTDINIFDYFEKDTLIISNSIN
                     GFYRAMSDISLIDLDFNINYNIIEDVSKNTDKLELIFSPNIDKIDLKRYNNIILYDYL
                     YNKGEYSYIYENKREESEIIKYYNKTDLLYLKNVVSNIVPSRDEFITIYKQALIKKEI
                     DLDMINIRETFNVIPLKFFTILNVFRELNLLDFNLNYEKNSVLIRILPKPQKKLDLNE
                     SLILNNLKNLEKQYNSSY"
     gene            9468..9980
                     /locus_tag="JAM15_11240"
     CDS             9468..9980
                     /locus_tag="JAM15_11240"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010076966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HAT6798826.1"
                     /translation="MDLKNFIRNIDDFPKPGIDFKDVTTLFKDGDAFKYAVDSIVEEL
                     KDKDVDLVIGPEARGFLMGTPVAYALGVGFVPIRKPGKLPGEVESYEYGLEYGTDTLE
                     IHKDAIKKGQKVAIVDDLLATGGTMEAAAKLVEKLGGEVVSMQFLIELKFLNGREKLS
                     NYDVNSLIKY"
     gene            10054..12261
                     /locus_tag="JAM15_11245"
     CDS             10054..12261
                     /locus_tag="JAM15_11245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HAT6798827.1"
                     /translation="MHDKELQEIIEKIKVYAPNANFEMVEKAYNLAKKAHEGQYRKSG
                     EPYFIHPLAVANILIEMELDIETITAGLLHDVVEDTEYTYEDIKKEFGKEVADLVDGV
                     TKLGQIKYRSKEETQSENLRKMFLAMAKDIRVILIKLADRLHNMRTLKYMPPEKAKYK
                     AKETLEIYGGIAHRLGISKIKWELEDRALRFMDPEGYYDLVSRVSMKRSQREDYIQGI
                     VELLKDKFKDLSIPCDVYGRPKHFYSIYRKMQKKHKTFEEIFDLTAVRILVDNVKDCY
                     AVLGIVHTLWRPIPGRFKDYIAMPKPNMYQSLHTTVVGPDGEPLEIQIRTHEMHNIAE
                     NGIAAHWKYKEGISSKESKVEEKLQWLRQMMEWEKDLKDPQEFMDALKEDVFNSQVYV
                     FTPKGDVIELPAESTPIDFAYRVHTNVGNKCVGAKIDGRIVPIDYKLQNGNIVEVLTS
                     SNSNGPSRDWLNIVKTPNAKSRIRQFFKKERREENVDRGNTILEREFKKHDIPQKDPL
                     VEKYMALVAKKFNQPSVEDLIATVGYGGIMSSQVVSKVKDLYLKEVKKAKKEQQIQEE
                     DLNKHNISETEYSKKRKKNASQGIIVKGLDNILVRFAKCCNPLPGDEIVGYITKGRGV
                     AIHRADCPNANNNGDFFQNRLVEVSWSLAGKGKFEAEIQIKAIDRRGIVNEITHIVAM
                     DKLSLNGINARKGKDSIVSINLLVEVNDTEELKILMKKLKAIPGVESIYRMTN"
     gene            12286..12735
                     /locus_tag="JAM15_11250"
     CDS             12286..12735
                     /locus_tag="JAM15_11250"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020814518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HAT6798828.1"
                     /translation="MRAVVQRVSSSKVTVDENTIGQINKGLLVLLGVTHDDKSSDVDY
                     MIDKILNLRIFEDENDKMNLSLMDIGGELLVVSQFTLYGDCRKGRRPGFSNAARPELA
                     NNLYEEFVKKAKDKGVTVGTGQFAAHMMVELTNDGPVTILLDSSKSF"
     gene            12750..13364
                     /locus_tag="JAM15_11255"
     CDS             12750..13364
                     /locus_tag="JAM15_11255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAT6798829.1"
                     /translation="MIIKKFVDSYFGVNTYVLGDEKTKKCAVIDPGGSLVETLSFVKE
                     NELNIEYIILTHGHGDHIGYVKDIKEKTGAKVVAHVDEKELLNDKNKNLSYTMRCGAQ
                     EFDADIYVNDKDKLELGELKMTFLHTPGHTQGCMCIRVEDEMFTGDTLFAGSIGRTDL
                     YSGDFNQMEKSLKKLCKYEDAVRVYPGHGPTSTLGVEKKTNPYM"
     gene            13455..15011
                     /locus_tag="JAM15_11260"
     CDS             13455..15011
                     /locus_tag="JAM15_11260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coproporphyrinogen III oxidase"
                     /protein_id="HAT6798830.1"
                     /translation="MLYVFLKGHDYKYEVAELIKLFTSEFKFKDSNANNNIESKHLIN
                     RLIYENGVLFSSTEYYENGNLKYESIQNIENMNLEFLDGFDSSKTIEEFLNRLDSESK
                     RNFKKLCKENIKKSMFVVLKQVFNSYVPWGILTGIRPVKIVHNLMDKKLDDNSIRTIL
                     KDNYFIIDEKIDLALEIAKRERLFMYPIDKNKISLYVSIPFCPTRCVYCSFPSNSLKQ
                     FGHLKREYVYKLIEEIKGFAKVIKETKKEVETLYIGGGTPTTLDEEELDLLINSLFNE
                     LDLSKIKEFTVEAGRPDTITEQKLRVLKKHNVSRISINPQTMNDDTLVKIGREHRVSD
                     LVDCFNMARRMGFDNINMDIILGLIDEDLNMVKNTLEEIKKLSPESLTVHTLAIKRAS
                     NLNINMDRYKEHLTQYEEMVKMIDLSMKYAKDMGLNPYYMYRQKHMLGNLENIGYAKE
                     GYECIYNIQIMEEKQSNYALGAGAISKFVYVDEDRIERVENVKNVEQYIERVDEMIKR
                     KKEEVYKNVD"
     gene            15001..16263
                     /locus_tag="JAM15_11265"
     CDS             15001..16263
                     /locus_tag="JAM15_11265"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HAT6798831.1"
                     /translation="MLTKAPRGTKDITPKEAYKWRYVENKFREICALYGYEEMVTPIF
                     EHTELFKRSVGDTTDIVQKEMYSFKDKGDREITLKPEGTAGVVRAFIENKLYADTQPT
                     KLFYVTPCFRYERPQAGRQRQFHQFGIEALGSDTPSMDAEIIALAVQFFNEVGLNDLV
                     VSINSVGCPVCRKEYNALLKEYLDSKADILCDTCNERREKNPMRVIDCKNPTCKENIK
                     DIPFIADHLCDDCKSHFDKLQEYLKEMNINFVIDKTIVRGLDYYRKTAFEIISNDIGA
                     QSTVCGGGRYDGLVEQLGGPKGISGIGFGLGIERLLLTLEGNGIEIENPQSTDIFIVT
                     IGEEANTRSFKLLKDLRQNHISADKDHIERSVKAQFKYSDKINSKFTIVIGDDELKND
                     TATLKNMKTSEQTTVKLSTLVEELKQKL"
     gene            16337..18124
                     /gene="aspS"
                     /locus_tag="JAM15_11270"
     CDS             16337..18124
                     /gene="aspS"
                     /locus_tag="JAM15_11270"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HAT6798832.1"
                     /translation="METLKGLKRTHYCGELREKNINEEVVLMGWVQKKRNLGGLVFVD
                     LRDTSGLCQIVFDTDVDKEAFEKAEKLGAEFVIAVKGKVCERQSKNPNMPTGDIEIFA
                     TELRLLNKSETPPIYIKDDDDVSEALRLKYRYLDLRKPSMQRNLKLRHKVMNITRNYL
                     SNNRFCEIETPFLIAPTPEGARDYLVPSRVNPGKFYALPQSPQLYKQLLMVSGMDRYF
                     QIVKCFRDEDLRADRQPEFTQIDCEMSFVEQEDVMSMIEGLLEAIFKEVLDVELALPL
                     PKMTYAEAMSKYGSDKPDTRFGYELTDISDVVCNCGFKVFADATQPGKSVRGINVKGK
                     ADDFTRKQISSLEEHAKTYRAKGLAWMKVGQEGVTSPIAKFFNEEEMNAILTKMNAEV
                     GDLLLFVADKNSIVFDALGQVRLEVANRLNLLDKNVYNLLWVTEFPVFEEDEETGTFS
                     AMHHPFTSPMDEDLDKLEEGDKSSLRAKAYDIVLNGYEIGGGSVRISNSDVQSRMFKA
                     LGFTEERANEKFGYLLEAFKYGTPPHAGLAFGLDRLVMLLAGTDNIREVIAFPKNQNA
                     VCPMTNAPTLAEDEQLEELSIKVDIKDNE"
     gene            18583..19815
                     /locus_tag="JAM15_11275"
     CDS             18583..19815
                     /locus_tag="JAM15_11275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HAT6798833.1"
                     /translation="MQEREELVLNPVPKEERVGWLAPLFNMLGSNIAISELMVGGTLI
                     LGMTLSNMIITSIIGNLILVAIIMIQGYIGYKEGLNTYVLAKGAFGEIGGKYLISLLL
                     GITSFGWFGVQAGVAGLSVQKIFPSVNLTLVTVILGLFMVVFALYGFKAMAKFNYLVI
                     PPLMILMVWGVFKAFSTYGVEAIYNYTPQTTMSMVEGLNIVVGLVIVGAIISPDQLRY
                     TRRVKDIWIISFLGLGIISLFQQVAAGVMSMGAPTWDITEVLANLGFGWVAFVILILA
                     SWSTNVSNAYSGGLALKTIFPNVKRNVLTLVAGLIGTIIAATGIIFKFQSFLSFLGIA
                     VPAIAGIMWCEYYFIQGRTYKHREGINWIAVISWLIGFAASYYSSKINFLIPPINGIV
                     VSMVIYYILMKCFGIKDK"
     gene            19829..20635
                     /locus_tag="JAM15_11280"
     CDS             19829..20635
                     /locus_tag="JAM15_11280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase"
                     /protein_id="HAT6798834.1"
                     /translation="MGRKVKIGIIQQHSVLGDVKKNIETAVEMIDDLGKHGADIICLP
                     ELFATGYNLESLGGVKTLELIREHNKYIEESMSEAAKRNNVYLISPYGTLEKGSTHVY
                     NSAVIFDRKGKIMGEYCKNHLWSLEAVYFKGGEKVEVYDADFGRFGVMICYDAGFPEV
                     SRELTLKGSEIIFIPSAWRIQDEDMWDLNVSQRALENTVYTVGVNLVSNDSNLILFGK
                     SKICNPRGTVITQLDTYREKYVLSEIDLDEIKKYREDIPYLKDRKSSYNI"
     gene            complement(20747..21616)
                     /locus_tag="JAM15_11285"
     CDS             complement(20747..21616)
                     /locus_tag="JAM15_11285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAT6798835.1"
                     /translation="MDLLHLKYFQTVARMEHITKASHKLNIAQPALSKTISSLEKELG
                     VQLFDRKGRYIVLNEYGRLFLKRVDSILDLVESSKKELQDTSLENSGEVKILSPAAAN
                     VLPSLLSNFRKLYPNITFNVSHTLPSSYKKSDFDLYISSSFTKLNSENSITLTCEEIL
                     LGVSINHPLSLKDEVYLSEVSDENFIVITKGENYREVIDILCESANFKPKIAFESDSP
                     YTIYALIKSLQGVGFICGKSWGLSQDPEIKLLHIKDIEFKRYLNLSWFSENYESKAVL
                     LFKNFLINYFKNI"
     gene            21987..23414
                     /locus_tag="JAM15_11290"
     CDS             21987..23414
                     /locus_tag="JAM15_11290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp14"
                     /protein_id="HAT6798836.1"
                     /translation="MKLTKSISSMLCLALVLSLSPVAYANEISRTTVENTLVGQDRYQ
                     TAVEVSKKGWSSANEAVVVNSESIVDALAVTPFAKLKNAPILLTEKNNLNSQTEKELK
                     RLGVKKVYIIGLSSSVSNDVQKQLESNNLTTDRVGGSDRYQTALSIAKKIEGLKDISE
                     IAVVNGYTGLADAVSIASVAATNGMVILPVSDASGISSFKDFIESKNINKSYIIGSTN
                     AVSDKIKQSLPNSERIGGADRNETNGKVIEKFYTSNKLNNVFVAKDGMKNQNQLIDAL
                     AVGVLASKENSPVLIVGEQLSATQKSVFLNKNATSITQVGSGGNENAFKELKDLQANS
                     NNKRVMYVTNTDKVNIRNDATIEASVIGYLNNGDEVEVLDVLKTGWVKIKYNEGIGYV
                     SGSYLTNNKPDNSNENIKIKYVKEKDGLNVRKGPSTEDEKIGHLSYGSKVETIEMFAT
                     GWVKIKYNGGYGYVSNDYLSDTPVI"
     gene            complement(23490..23759)
                     /locus_tag="JAM15_11295"
     CDS             complement(23490..23759)
                     /locus_tag="JAM15_11295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798837.1"
                     /translation="MKFEYYYLIQDIAGILLAFIGLRMSIIGFRILSMKGISINTLLI
                     VIKYCLFTIAGLNLLISKFGIRHWIWSVCMLIISIIINPRIKVSK"
     gene            complement(23762..25204)
                     /gene="nhaC"
                     /locus_tag="JAM15_11300"
     CDS             complement(23762..25204)
                     /gene="nhaC"
                     /locus_tag="JAM15_11300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HAT6798838.1"
                     /translation="MKMNTERKIPSFRYSLLVMLAIIALTSVGIVVFNASITTMFLLS
                     WLIVVPAAMKLGYTNDEIEAFGFEVGKDAFQSNLIILSVGVLIAAWIAAGTIPTVVYS
                     GLTIITPKYFLLTTLIVCSLTSVATGTSWGTLGTSGIAMMSIGTSMGIPLGLTAGAVI
                     SGAFFGDKMSPLSDSTNLAAAVCKTDVITHMKHMFYTTGPAYVICIVLYTVIGFKYSN
                     NTIDYVQINQIKDVLNSNFHIGLVAMIPIIFLLLLLLLQKPPIISILSSAIMGLIIAV
                     FQEGEKIGDVLNYMLSGFTIDTGFVYADKLLNRGGIMSMAETVLLVFVVFVIAGILQK
                     TGFLEVLLQPLITKIGKSRTKLVGSTFIVSYFANAFSSSMMFTSVFVGTLMSPIYKEF
                     KLKPQNLSRIIEDTATLGGPLIPWNSNAVFCAQTLGVSPLEFIPYCFLSWITPIISFI
                     YGVTGFTMLTYTDDEIEELEVFDTAQRRVD"
     gene            complement(25229..26395)
                     /locus_tag="JAM15_11305"
     CDS             complement(25229..26395)
                     /locus_tag="JAM15_11305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAT6798839.1"
                     /translation="MNYNFNEIVDRSNNFSSKWSEMEKKYGTNDLLPMWVADMDFKAA
                     PCIIDSLKNRLEQEIYGYTTRPDSYNESIVNWLDRRHNWKIKSEWLIYSPGVIPAISL
                     LINELTKANDKIMIQEPVYSPFNSVVKNNNRELIISPLQKLENGNYIMDYEDIENKIK
                     DVKLFILCNPHNPVGRVWTKDELKKLGDICIKHNVKIISDEIHSDIILKKHKHIPMAS
                     ISKEFEKNTITCMAPTKTFNIAGLQSSYVILPDEKDYKLLDDAFTRIDIKRNNCFSLV
                     ATEASYNNGESWLESFLEYLESNIDFAIKYINENMPKLKVRKPEGTYLLWVDFSALGL
                     SDEELESVLVQKGKVALNQGNSFGIGGSGYQRINLACPRSMLEEALIRIKNAIN"
     gene            complement(26620..28740)
                     /locus_tag="JAM15_11310"
     CDS             complement(26620..28740)
                     /locus_tag="JAM15_11310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAT6798840.1"
                     /translation="MKQMELAIVSLKKDAGEIYENQIRQFLGDNLKINLYSFEEGNLK
                     FFKEKLILLSAYLKYDEIVKLSHYDAQIIVPKLTFEKNSIDMISKLEKDKIIYVYNLS
                     KDMAIETISLIHRLGIDNINILPCYPEIEFTPTDAVILTPGEKILPKFKNCEVVDLKY
                     RIIDLSCIVEIATKTKLKHLIKDDLIKKYVEKIIPTSYSTGELLLDANKFERQFDLLL
                     SIIDDGIICTNNDGIIQFYNHMARKILSINANEMIDSFVGDCIKDINFQNILTNKTPF
                     FEKLIKINHIDINLEIKHIQLNVFDGFILKMTKFSQLEKKQAKLRAQLVNSGNISKYT
                     FDDILGSSIQTINTKKIANKMAQSNSSILIIGESGTGKELFAQSIHSASRRKDGPFVA
                     VNCSTFQENLLQSELFGYDEGAFTGAKKGGKIGLFELANNGTIFLDEIGEMDLNSQSK
                     LLRVIQEKQVRRIGSNNVIDIDVRIIAATNRNLKELVSKNMFRRDLYFRLNVLPLKIH
                     PLRERAADIFEIFGSLKYDIPCNFILSEEVKEIFKMYRWEGNVRELRNLGEYFCYLGK
                     DIIEICDLPEYILDTIDSNYSRTVCNKVSDNIKKYQFNIGKDKNIMKYDYNFKRSLDE
                     YIFILDNLKKAYDLKERIGRKSLCKIALEENRFLTEQQIRNMLLELQDFGLVDILVGR
                     GGSIITSKGVEFLKNTNRSNKLNS"
BASE COUNT        11222 a         3244 c         4928 g         9386 t
ORIGIN      
        1 ttggataaat atgatatagt aaataagaaa aaatttgaaa aaaatcacta taaatgagta
       61 ataaatataa atagtgtata ctaatgggat ggaaaatgtc cactattaac tttattaccc
      121 cacatatata agataaaatt attaatataa aatataatct atcgacaatg aatagacttt
      181 taaataaact taatataaaa ttaattaaat aagtgcttaa aaacgattta ctttaatgat
      241 agaatcatat taaaggagga taattttatg gatataaaga ataaaattaa atctatattt
      301 ttaccagaaa aaaatgacta tttagatgat gaagaatttg agtatgatat agaaaataat
      361 gaagaagatt taaaggaaga taacaaagta catttaaatg atttaagcag agtaaaatat
      421 gattacagag agttaaaaga catagaaaac caaacagaag agatgtgtct gctagcagta
      481 aagcaggatg gtactataat tgagtttgta aaggacaaga cttataaagt atgtatggaa
      541 gcagtaaaac agacatataa agctcttaag tatataacaa atcaaaatga ggatatttgt
      601 atagaagcag taaaacagaa ctacagagct ttgtactaca taaataataa gacagaaaat
      661 gtactaattg aggctataaa aaatgcatca acttatgatg tcatggaagt atttaaattt
      721 gtggaagatc aaacagaaga tgtatgtcta gcatttatag aaagggcatc taaaaatgat
      781 gttgcagaga tattaaaagg aataaaagag caaactccag ccatatgttt agaagctgta
      841 aaaaaagatg gaaaatcttt agcttatgta aaggaacaaa gtaatagtat atgtttagaa
      901 gctgtaaaag aaaactacag tgcactatct tgtgtaaaag agcaaacaga agaaatatgt
      961 atagaagcag taaaacagaa tgactttgca ttgtattatg taaatgaaca gacagaaaaa
     1021 atatgtatgg aagcagtaaa aagaagttat atggctctac agtatgtaaa taagcaaaca
     1081 gaagagattt gtatggaagc agtaagaatt gatggaagag cattacagta cgtaaaagag
     1141 caaacagaag aaatttgctt ggagtcagtt agacaaaatg gaaaagtatt gcaatatgta
     1201 aaaaaacaga ctgaaaatat atgtatagaa gcagtaagag gttcatttga agaacttgaa
     1261 ataaaagaaa tattaagtta tgtaaagata ccaacagaaa gaatatttgt agaagcagta
     1321 aagcaaaatg gaaaaattct taaatatgta gaaaatcaga cagaattaat atgtttagag
     1381 gcagtaagag aaaactataa tgctttagct tatgtaaagg aacaaacaga agagatttgt
     1441 ttagaagcag ttaatcaaag ttatgaagcg cttaaatatg tgaaagaaca aacagaagaa
     1501 gtttgtctaa aagcagtaaa acaagattat agaatgttga aatatgtaaa taatcaaaca
     1561 gaaaaaatat gtttagaagc agtaaagcaa aattatagag ctttagaatt tgttgataat
     1621 caaacagaaa aagtttgtct tgaagcagta aaacagaata gaaaagcact acagtatgta
     1681 aaacaaaaac aaagttaaaa ggctaaaata tatagaaaat atatgcaaat aaataaaatt
     1741 tgatattttg taataaataa aatgggtatc tcaaaatgaa ctttttagtt tgtgaggtac
     1801 tctttttata tgaaataaaa tatattttta gccttttaac aatggggaaa aggtttattt
     1861 ctattttgac ataggctttt tatgcatata aagcttgata aaattgtttt attataattg
     1921 ttttgttata taaataataa taagaaaatt atataggtct ttttttgacc agttttgcat
     1981 ttttaacaac tagttttgta aagtatattg aattttctca aaaaagaatg tactctatat
     2041 atgtaaaatt tttttggagg taaaaatgtt taaaagatat gctgaaaaaa tgacatctgt
     2101 tttaatttgt aataatatga tagataataa tgaatctaaa gtctattctt atggatttga
     2161 aatattaata gctttcatag ttaatataac caccatgctg tttataggtt ttttatttgg
     2221 taaatttaca tatgtattat tttttttaat gtgttattgt ccaataagac aattttcagg
     2281 agggtatcat gcagacaatt attttagatg cttattaacc tttattttta taattttatc
     2341 tacaatctta attatagaaa atataaatat agacttattt aaaaatatta ttatgattat
     2401 tgcaagtgtt agttgggttg gaatttgtgt tctgtgtcca atagaacata ggagtaaccc
     2461 tataagtgat agggaaaagt ttgtttataa gaaaactgct atatttatat ctacagtagt
     2521 gttattgata acaattttaa gtttttcttt gagtatattt gtagattatt tcacatatag
     2581 cgtatttgcc atgttttgga tttttgtgat gttagtatta ggtaagttaa aagctaaagt
     2641 ataagtaaaa tatgtatgag ggagagttaa gttatgaaaa agtttattgt aagatttatg
     2701 aagtttgcta gctcattggc acttagcact gctattttgt cagctaatag tacctgtcct
     2761 tggattattc atcagcctaa agtacccaaa gaaatcagca atctaaagaa gacaaattaa
     2821 atacaagcac ttatttatac aaaattatca ggaaaaaaga aattattata ttttaataag
     2881 attaaaacaa tataaaatca gatacaaaat ttattttatt tattttatag gagcctaata
     2941 cctatttggt aatatattag tgcgccaatt tagggggata tagtgtattt aatgaaatga
     3001 cttacggaga gtaagtcatt tttgtattgt atgtatttta tgtaaactta tgatataatg
     3061 aagggtaaag tttaattaaa ataataaaaa actttagtat agatagtaat ttaggaggta
     3121 gggtatgagt atgatacata aattttctat gaatggatat aatatcgttt tagatgtgaa
     3181 tggtggagct gttcatgtgt tagatgatgt tgcatacgat ttgttagatt tttataaaga
     3241 aaaaagtaaa gaagaaatat tagagatatt aaaatcaaaa tatcaagaag aaaaaataaa
     3301 tgaagcatat gaagaaatat taaatttgga aaaagaaggt cttttataca cagaagatac
     3361 atatcaatat catccaagct ttgtacatag agagcctgta gtaaaagctt tatgtttaaa
     3421 tgtagctcat gattgtaact taaaatgtaa atactgtttt gcagctcaag gtgattttgg
     3481 aggagaaaaa gaacttatga gttttgaagt tggtaaggca gcaattgact atttgattgc
     3541 taattcagga agtagaaaga acctagagat agatttcttt ggtggagagc ctttgatgaa
     3601 ctttgaagtt gtaaaacaac tggttgacta tggaagaagt gtagaaaaag attataataa
     3661 aaatataaga tttacaataa ctacaaatgg tgtactgtta aatgatgaga ttatagatta
     3721 tataaatgaa aatatgcata atgtagtttt aagtttagat ggaagaaaag aagttaatga
     3781 taatatgaga ccaactttaa atgataaagg aagttatgat attacattac cacgatttaa
     3841 gaaacttgtg gaaaaaagag caaaagataa gtattattat ataagaggta cttttacaag
     3901 agataattta gatttttcaa aagatgttat gcattttgca gatttaggat ttaaattaac
     3961 ctctgtagag ccagtcgttg gagatgagag taatccatat gcacttagag aagaagattt
     4021 acctaagata tttgaagagt acgaaaaatt tgctgtagag tatgcagata gacaattaca
     4081 agaagatgga tttaaatttt tccattttat gatagaccta aatcaaggtc catgtgtaat
     4141 aaagagaata actggatgtg gagctggaaa tgagtatctt tctgtaactc caaatggaga
     4201 tatctatcca tgtcatcaat ttgttggaaa tgaagaattt aaaatggcaa atatatttga
     4261 tgaagaaata gtacttccag aaaatttaaa aaatatgttt agagaagctc atgtatatac
     4321 taaagaagag tgtaaacaat gttggaataa gttttactgt tcaggtggat gtcatgcaaa
     4381 tgcgataaac tttaataatg acatatcaaa accatatgaa ttaggctgtg aaatgcaaag
     4441 aaaacgtaca gagtgctcta taatgataca agctaagtta atgttagaag gagcaaccaa
     4501 ctaaatttat attttaaagg agttgtttat atatgattag agattattta gaagataaac
     4561 ctttaattga cgaaagtgta tttgttgcaa aatcagcaga tgtaattgga aatgttaaaa
     4621 taggcaaaga ttcaagtata tggtacaatg cagtagttag gggtgatgaa gaaccaataa
     4681 ctattggaga aaacactaat atacaagatt gttctatagt gcatggagat acagaaacta
     4741 taattggtaa caatgtaaca gttgggcata ggtctatagt tcatggttgc aaaattagtg
     4801 ataatgtgtt aattggtatg ggttcaataa tattggataa tgctgaaata ggagaatata
     4861 ctctgatagg agcaggtaca ctaattacat ctaataagaa gtttccacca ggtgttttga
     4921 taatgggttc tcctggtaag gttgttagag agcttacaga agaagataaa aaatatattg
     4981 atgaatctta tgaatggtat ttagaggcag cacaaaatca aaaatattag tttaaagagt
     5041 ggttgtttca aaacatattt aaatctgttt tgaggcaacc actaatttat tttattagat
     5101 tttgttgata ttttagtttt caaaaagtat ttgattaaac cagatataaa atgtcaaaaa
     5161 taaaaattaa ctgagttaaa taattttaat aaaattggta gtatatgtga taaaattaaa
     5221 tattaaagag gatataggat attagaatat caattggtga aataatgtca tatacgataa
     5281 attaaggtgt aagtttttgg gtatacctat cttaggagtg aaaagatttg agaataagtt
     5341 atagaaattt aaagcgatat agagaaattg gatatatttt aataaagtat ggttttagtt
     5401 ttattgtaga aagactaaat atagaaggaa ttgcctataa aataccacta tttgacccac
     5461 cagaagaaat aaaaaatatg acaactggtg agagaatgaa aagagtttta gaagaactag
     5521 gacctacata tataaaaata ggacagatat tgagcacaag aaaagacttg ttagaccagg
     5581 atataattga tgaaatatca aaactcagag atgatgtaga gaaatttgat tcaaatatag
     5641 ctattgatat atttaaagaa gaagtgggtt taagtataga agaaatattc ttagaattta
     5701 aagaagaacc aatagcagca gcttcaattg gtcaagttta tgaaggtgta cttaaaacgg
     5761 gagaagaagt aatcgtaaaa attcaaagac caaatataga gaaaataata aaatctgatt
     5821 tagagattct tagaactatt gcaaatactt taaaagattt aaaaaaggat tttaatttag
     5881 atttagtaca gatgattgaa gaatttcaaa ctcaattaat gagggaactt gattatacat
     5941 ttgaagccat aaatgcaact aaattctcta ggatatttaa aaatagtgat gaagtatata
     6001 tacctaaagt atactcagaa tataatacta agaaaatttt agtaatggag aaagttaatg
     6061 gtacaaagtt aagtgatgta gaaaaaataa ggagactagg ttataacaca aaaactattg
     6121 ttgaaatagg agttaggtca ttttttacac aggtattatc tcatggattt tttcatgcag
     6181 acccacatcc aggtaatata ttcgtagttg ctaaaaataa gatagcatat atagattttg
     6241 gaatgattgg aattattgat aataaaactt taaaccaatt aaatgaaatt gcattagcag
     6301 gtgtagaaaa gaatgttgac aagataatat atctattgat agaaatggat gcattaaatg
     6361 gagaggctga tattaaggga cttagacagg atttacttta tctaatacat tattactatg
     6421 atatttctat agaaaaaata aatgtaacag atatattaaa tgaactattt agatttttta
     6481 gacagtacaa aatagtcatg cctgcacaat ttgtaactct tgcaaagaca gttataacat
     6541 tagaaggaac aagtagaact ttaaacacag atttttcttt tggttctatg ggaaaagagt
     6601 ttatgaaaca tcattataag agtaaattta accctaaaaa tgttgtttta agttcaagac
     6661 aaaatgtaga agaaatatta ctggacataa aaactattcc aaagcaatta aaagcaattt
     6721 taaaaaatat agaaagaaat aatataaaaa tgcaaattga agatgttaaa atgacgaggt
     6781 tagaaaactg tataatagag ctaacatctc aaatatcttt gagtttagtg ttggcatcta
     6841 ttatagtagg ttcttctctt ataattgcat ctccaaatat agaaaataat atatggataa
     6901 aatttactgc aatagctggt ttctttatat cctttataat aggcctttgc ttagttataa
     6961 gaagtattag gtcaaaatac aaaaaagatt agggggaatt aaatttgaaa aaatggatat
     7021 tgaagtataa aggtaagata gaggaaagtg aatttagcaa aaaacttaat atttccccgg
     7081 aaatctgcca aattttaaaa aatagaggga tatgtactga aaaagattca gaaatattta
     7141 tgaatccatc tttagattat ttaagagacc cttttttaat gaaagatatg caaaaagctg
     7201 ttgatagaat aaagttagca gttgagaaga acgaaaaaat ttggatttac ggagattatg
     7261 atgttgatgg tgtatcatct acatccatct tgtgtttata ttttaagagt ataggttaca
     7321 atgttgatta ctatattcct aatagattag aagaagggta tggtataaat gaagatgcta
     7381 ttaagcttat aagctctagg ggatgtgact tgattataag tgttgactgt ggaattacat
     7441 cagtgtctga ggtcaataca gcgaatgatt tgggcataga tgttataatt acagaccatc
     7501 atgaatgtca aagtgaaatt ccatcagcct ttgcagtaat aaatccaaaa caagaagatt
     7561 gtaattatcc atttgattca ctatgtggat gtggtgtagc atttaaaatg attcaagcct
     7621 tgactccaaa agaagaattt aaaactagta tgtataatta tttggaaata gtaacactag
     7681 caactatttg tgatattgtt ccacttatag atgaaaatag aataattgta aaaaatggtt
     7741 taaaatcaat gaaagaaggc aaaaatattg gattaaggga gcttataaaa gtttgtggtg
     7801 tagaaagtga taagataggt tcttctcata taggttttgc aataggtcct aggataaatg
     7861 cttcaggtcg attgggatat tcttacttag gagtagagct atttactact caatcacaag
     7921 aagaggcagt agaaatagct agtatattgg aagaaaaaaa taatgaaaga cagatgatag
     7981 aagctaagat gtatcatgaa gctgaaaaaa tgctaaagtc taatagcaga tacaatgatg
     8041 acaaggtgtt ggttttagcc aaagagggtt ggcaacatgg aataatagga attgtagcat
     8101 caaagttaac tgaaaaatac tacaaaccaa caattcttct aggtatagaa aatggggagg
     8161 ctactggttc agcgaggtca ataaaaggat ttaatatatt tgaagctctc ataaagtgca
     8221 aagacttgat gactaagttt ggtggtcatg aacaagcagc agggttatcc ttggattcag
     8281 acaatgtaga aattttagca aatgaaataa ataaatttgc agattataat ttaactgaag
     8341 atgatatgat agagaatgta aatgttgagt ttgaattaca agaaaatgta ataaatttaa
     8401 atcttgtaga agaattacat aagttagaac cctttggatt aaataatcct aatcctagat
     8461 ttatagttag aaattatatt ttaaaagatt tgaaagttat aggtaagaat caacaacatc
     8521 tgaaattaag tatagaaaaa gagaaaagct atgaatgtat aggatttaat atgagtcatt
     8581 taaaatcaat gtataaagta ggagacaaag tagatgtact attccaatta gatgaaaata
     8641 actatatggg aaataggaaa gtacaatttt tacttaaaga tatacgattg gctcgaccta
     8701 aaagtgcaag taatgacaaa ctttcattga aattaatgtc aaaaataata ccaaaagata
     8761 ctcaaagcct gtataatata tctgtgtctg attttgaatt atttgatgga aatacagata
     8821 taaatatatt tgattatttt gaaaaagata cactaataat atctaattct ataaatggat
     8881 tttatagagc aatgtcagat atatcactta tagatttgga ttttaacata aattacaata
     8941 ttattgaaga tgttagcaaa aatactgata aattagagct tatattttct cctaatattg
     9001 ataaaataga cttaaaaaga tataataata ttattcttta tgattattta tacaataaag
     9061 gcgaatattc gtatatatat gagaataaaa gagaagaaag tgaaattata aaatattata
     9121 ataaaacaga cctattatat ttaaagaatg tagttagtaa tatagttcca tcaagagatg
     9181 aatttataac aatttataaa caagcactca taaaaaaaga aattgatttg gatatgataa
     9241 atataaggga aacttttaat gtaattccat taaaattttt tacgatatta aatgtattta
     9301 gagaattaaa tttacttgac tttaatttaa attatgaaaa aaattctgta ctcataagaa
     9361 tattgccaaa accacagaaa aaattagact taaatgagag tttaatactc aataatctaa
     9421 aaaatttaga aaaacaatac aatagcagtt attaggaggc gtttcccatg gatttaaaaa
     9481 actttataag gaatattgat gatttcccaa agccaggtat agattttaaa gatgtgacaa
     9541 ctctatttaa agatggagat gcatttaaat atgcagtgga ttctatagtt gaagaattga
     9601 aagataaaga tgtagattta gtaatagggc cagaagcaag aggatttttg atgggtacac
     9661 ctgtagcata tgctttagga gtaggatttg ttccaattag aaaacctgga aagttaccag
     9721 gtgaagttga gagttatgag tatggattag agtatggtac agatacttta gagatacata
     9781 aggatgcaat taaaaagggt caaaaagtag caatagtaga tgatttattg gctactggtg
     9841 gaactatgga agccgctgcc aagcttgtag aaaaattagg tggagaagta gtttctatgc
     9901 aatttttgat tgagctaaaa ttcttaaatg ggagagaaaa gttgtctaac tatgatgtta
     9961 attctcttat aaaatactag tacttttata atagttggta taacaccaac tattttcata
    10021 tatattaaaa ttttatacaa aataggtggt tatatgcatg ataaagaatt acaagaaata
    10081 attgaaaaaa taaaagttta tgcacctaat gcaaattttg aaatggttga aaaagcctat
    10141 aatcttgcaa aaaaagcgca tgaaggacag tatagaaaat ctggggaacc atactttatt
    10201 catccattag cagttgcaaa tattttaata gagatggaat tagatattga aactataaca
    10261 gcaggtttac ttcatgatgt tgtagaagat acagaatata cctatgaaga cataaaaaaa
    10321 gaatttggca aagaagtagc ggatttggtt gatggagtaa ctaaacttgg tcaaataaaa
    10381 tatcgttcga aagaagaaac tcaatctgaa aatttaagaa aaatgttttt ggcaatggcg
    10441 aaggatataa gggttatact tataaaactt gctgatagat tgcacaacat gagaacatta
    10501 aaatacatgc ctccagaaaa agcaaagtat aaagcaaaag agacacttga aatttatggt
    10561 ggtatagctc atagattagg aatttccaag ataaagtggg aactagaaga cagagcatta
    10621 agatttatgg acccagaagg gtattatgat ttagttagta gagtatcaat gaagagaagt
    10681 caaagagagg attatattca aggaattgtt gaacttctta aagataagtt taaagattta
    10741 agtataccat gtgatgtata tggtagacca aagcattttt acagtatata tagaaagatg
    10801 caaaaaaaac ataagacttt tgaagagatt tttgatttaa cagcagtaag gatattggtt
    10861 gataatgtaa aggattgcta tgcagtactt ggtatagttc atacattatg gagacctatt
    10921 ccaggaagat ttaaagatta tatagcaatg ccaaaaccca atatgtatca atcattacac
    10981 accactgttg taggtcctga tggagaacct ttagagatac aaataagaac tcatgagatg
    11041 cataatatag ctgaaaatgg tatagcagcc cattggaaat ataaagaagg tatctctagc
    11101 aaagagtcaa aggttgaaga aaaacttcaa tggttgagac agatgatgga gtgggaaaaa
    11161 gatttaaaag acccacaaga gtttatggat gcacttaaag aagatgtatt taatagtcaa
    11221 gtttatgtat ttacgccaaa aggagacgta attgaattac cagcagaatc aacacctata
    11281 gattttgcct atagggttca tacaaatgta ggtaataaat gtgtaggagc taaaattgat
    11341 ggaagaatag ttcctattga ttataagctt caaaatggta atattgtcga ggtacttaca
    11401 tcatctaatt ctaatggacc aagtagggat tggcttaata tagtgaaaac tccaaatgca
    11461 aaaagtagaa ttagacaatt tttcaagaag gaaagaagag aagaaaatgt tgaccgtgga
    11521 aatacaatat tagaaagaga atttaagaag catgatatac cacaaaaaga ccctcttgtt
    11581 gaaaaatata tggcattagt tgctaagaaa tttaatcagc caagtgttga ggacttaatt
    11641 gccactgtag gttatggtgg tataatgtca tctcaagtgg tatctaaggt aaaagaccta
    11701 tatttaaaag aggttaaaaa agctaaaaaa gaacaacaga tacaagaaga agatttaaat
    11761 aaacacaata taagtgaaac agaatacagt aaaaagagaa agaaaaacgc atcacaagga
    11821 attatagtaa aagggcttga caatatctta gtaagatttg ctaagtgttg taatcctctt
    11881 ccaggagatg aaattgtagg atatattact aagggtaggg gagtagccat acacagagct
    11941 gattgcccaa atgcaaacaa taatggtgat ttcttccaaa atagattggt ggaggtttca
    12001 tggagtttag caggaaaagg taagtttgaa gcggaaattc aaataaaagc tattgacaga
    12061 agaggaattg ttaatgaaat aactcatatt gttgcaatgg ataaacttag tttaaatgga
    12121 ataaatgcaa gaaaaggtaa ggatagtatt gtaagtataa acttacttgt agaggttaat
    12181 gacacagagg aattaaaaat tctaatgaaa aaattaaaag caattcctgg tgtagaaagt
    12241 atttatagaa tgacaaatta gagttaaaat aatagggagg aaactatgag agcagtagtg
    12301 caaagagtat cttcatctaa agttacagta gatgaaaaca ctataggtca aataaataag
    12361 gggttactag tattgttagg agtgactcat gatgataaat caagtgatgt agattatatg
    12421 attgataaaa tattgaatct gagaattttt gaagatgaaa atgacaagat gaatttatct
    12481 ctaatggata taggtggaga gcttttagta gtatctcaat ttactttata tggagattgc
    12541 agaaaaggaa gaagacctgg atttagtaat gcagctagac cagaacttgc aaataacctt
    12601 tatgaagaat ttgtaaaaaa agcaaaagat aaaggtgtga cagttggcac aggtcaattt
    12661 gcagctcata tgatggtaga gttaactaat gatggtccag taacaatact attagactca
    12721 agtaaatctt tttaaggggg aaaactttaa tgattataaa aaaatttgta gatagttatt
    12781 ttggagtaaa tacttatgta ttaggtgatg aaaagactaa aaaatgtgca gttatagacc
    12841 caggtggaag tttagtagag acattaagtt ttgtaaaaga aaatgaatta aatattgaat
    12901 atattatcct tactcatggg catggagacc atataggata tgttaaggat attaaagaaa
    12961 aaactggtgc taaagtagtt gcacatgttg atgaaaaaga attattaaat gacaaaaata
    13021 aaaatctaag ttatacaatg agatgtggag cccaagagtt tgatgcagat atctatgtga
    13081 atgataaaga caagcttgaa cttggtgaat taaaaatgac tttcttgcat actccaggac
    13141 atactcaagg atgtatgtgt ataagagttg aagatgaaat gttcacagga gatactttgt
    13201 ttgctggaag tattggtaga actgatttat atagtgggga ctttaaccaa atggaaaaat
    13261 cacttaagaa attatgcaaa tatgaagatg ctgttagagt atatcctgga catggaccaa
    13321 ccagtactct aggggttgaa aagaagacaa atccttacat gtaattttat attagtattt
    13381 aaaaaagtat aaaatattta ataactatat tagtgagggg gttcttctac tgttaaatag
    13441 aaggagttaa gttgatgttg tatgtttttt taaaaggaca tgattataag tatgaagtag
    13501 cagaacttat aaaattgttt accagtgaat ttaagtttaa agactctaat gctaacaata
    13561 atatagagtc aaagcattta ataaatagat tgatttatga gaatggtgta ttattctcaa
    13621 gtactgaata ctatgaaaat ggaaatttaa agtacgagtc aatacagaat atagaaaata
    13681 tgaatcttga atttttagat ggatttgata gtagcaaaac gattgaagaa tttcttaata
    13741 gactagatag tgaaagtaag aggaacttta aaaagctgtg taaagaaaat atcaaaaaaa
    13801 gcatgtttgt agtgcttaaa caagtattta attcttatgt accatgggga attttgactg
    13861 gtattagacc agtcaaaatt gtccacaatt taatggataa aaagctagat gataatagca
    13921 taagaaccat tctaaaagat aattatttta taatagatga gaaaatagat ttagctcttg
    13981 aaatagctaa aagagagcga ttatttatgt atcctataga taaaaataaa atttctcttt
    14041 atgtaagtat tccattttgt ccaactagat gtgtatattg ttcatttcct tcaaattcat
    14101 taaaacaatt tggacattta aaaagagaat atgtttataa attgattgaa gaaattaagg
    14161 ggtttgccaa agttattaag gagactaaga aagaagttga aactctatat attggtggtg
    14221 gaactccaac tacacttgat gaggaagaat tagatttgct tataaattca ttgttcaatg
    14281 aattagattt aagtaaaatt aaagaattta ctgtagaagc aggtagacct gacactatta
    14341 cagaacaaaa actaagagtg ttaaaaaaac ataatgttag tagaattagt ataaatcctc
    14401 aaactatgaa tgatgatacc ttggtaaaga ttggaagaga gcatagagta tctgatttag
    14461 tagattgctt taatatggct cgtagaatgg gatttgataa tataaatatg gatataattt
    14521 taggtcttat agatgaagac ttaaatatgg taaagaacac attggaggag ataaaaaaac
    14581 tttctcctga aagccttaca gttcatacat tagccataaa gagagcatcc aacttaaata
    14641 taaatatgga taggtataaa gaacatctaa cacaatatga agaaatggta aaaatgatag
    14701 atttatcaat gaaatatgca aaagatatgg gattaaatcc atattatatg tacagacaaa
    14761 aacatatgtt gggaaattta gaaaatatag gttatgctaa agaaggatat gagtgcattt
    14821 ataatataca gattatggaa gaaaaacaaa gtaactatgc attaggtgca ggtgctatat
    14881 cgaaatttgt ttatgtagat gaagatagaa ttgaaagagt agaaaatgta aaaaatgttg
    14941 aacaatacat tgaaagagta gatgaaatga taaaaaggaa gaaagaagag gtatataaaa
    15001 atgttgacta aagctcctag aggaactaaa gacataactc caaaagaggc ttacaaatgg
    15061 cgttatgtag aaaataaatt tagagaaata tgtgctttat atggatatga agaaatggta
    15121 acacctatat ttgaacatac agaacttttc aagagaagtg ttggagatac tacagatata
    15181 gttcaaaaag aaatgtattc ttttaaagat aaaggtgata gagaaattac cctaaagcca
    15241 gaaggtacag caggcgtagt aagagcattt atagaaaata aattatatgc agatactcaa
    15301 ccaacaaaat tattttatgt gacaccttgt tttagatatg aaagaccaca agctggtaga
    15361 caaagacaat ttcaccaatt tggaatagaa gcacttggaa gtgatactcc ttcaatggat
    15421 gctgaaataa tcgcactagc tgttcaattt tttaatgaag ttggattaaa tgatttggta
    15481 gtgagtataa attcagttgg ctgtccagtt tgtagaaaag agtacaatgc tttattaaaa
    15541 gagtatcttg actcaaaagc tgatatattg tgtgatactt gcaatgagag aagagaaaaa
    15601 aatccaatga gggttataga ctgtaaaaat cctacatgta aagaaaatat caaagatata
    15661 ccatttattg cagaccattt gtgtgatgat tgtaaatctc actttgataa acttcaagaa
    15721 tacttaaagg aaatgaatat aaactttgta attgataaaa caatagttag aggcttagat
    15781 tactatagaa aaactgcttt tgaaattata tctaatgata taggagctca aagtactgta
    15841 tgtggtggag gaagatatga tggtcttgtt gaacaattag gaggaccaaa aggtataagt
    15901 ggaattgggt ttggactagg aattgaaaga cttttactta cacttgaagg taatggaatt
    15961 gaaatagaaa accctcaatc tacggatata tttatagtaa ctataggtga agaagcaaat
    16021 acaagaagct ttaaattatt aaaagacttg agacaaaatc atataagtgc agataaagac
    16081 catatagaga gaagtgttaa agcacaattt aaatattcag ataaaataaa ttcaaaattt
    16141 acaatagtaa ttggagatga tgaacttaaa aatgacactg cgacattaaa aaatatgaaa
    16201 acatcagagc aaactactgt aaaattaagt acattagttg aagaattaaa gcaaaagctg
    16261 taaaataaga aagtatgatg ttttgtgtat tagataaata tatagcatta aaattaaata
    16321 aaatggaggt agtatcttgg aaactttaaa gggtttaaag agaactcact actgtggaga
    16381 gttgagagaa aaaaacataa atgaagaagt cgtacttatg ggatgggtac agaaaaaaag
    16441 aaatttaggt ggtcttgtat ttgttgattt aagagataca agtggattat gtcaaatagt
    16501 ttttgataca gatgtagata aagaagcttt tgaaaaagct gaaaaattag gggctgaatt
    16561 tgtaatagct gtaaaaggaa aagtatgcga aagacaatct aaaaacccta atatgccaac
    16621 tggtgatata gaaatatttg caactgaact tagactttta aacaagtcag aaactccgcc
    16681 tatttatata aaagatgatg atgatgtttc tgaagcacta agattaaaat atagatactt
    16741 agatttaaga aaaccatcta tgcaaagaaa tttaaaatta agacataaag taatgaatat
    16801 tacaagaaat tacttatcaa acaatagatt ttgcgaaata gaaacaccat ttttaatagc
    16861 tccaacacca gaaggagcaa gagattatct agtaccaagt agagttaatc caggaaaatt
    16921 ttacgcatta ccacaatcac cacaattata taaacaatta ttgatggtaa gtggtatgga
    16981 taggtatttc caaatagtta aatgctttag agatgaagat ttaagagcag atagacaacc
    17041 agagtttaca caaatagact gtgaaatgtc ttttgtcgag caagaagatg ttatgagtat
    17101 gattgaaggt ttgcttgaag cgatatttaa agaagtttta gatgtagaat tggcacttcc
    17161 acttcctaag atgacttatg cagaagctat gtctaaatat ggttcagata aaccagatac
    17221 tagatttgga tatgagttaa cagatatatc tgatgttgtt tgtaactgtg gatttaaagt
    17281 gtttgctgat gctacacaac caggaaaaag tgttagaggt ataaacgtaa aaggcaaagc
    17341 tgacgacttt actagaaaac aaatatcatc actagaagaa catgctaaga catatagagc
    17401 aaaaggtctt gcttggatga aagtaggaca agaaggagta acttctccaa tagcaaaatt
    17461 ctttaatgaa gaagaaatga acgctatact tacaaaaatg aatgctgaag taggagattt
    17521 acttttattt gtagctgata aaaactcaat agtatttgat gctttaggac aagttagact
    17581 tgaagtagca aataggctta atctattgga taaaaatgta tataacttac tatgggtaac
    17641 tgagttccca gtttttgaag aagatgaaga aacaggcaca ttttcagcaa tgcatcaccc
    17701 atttacatca cctatggatg aagatttaga caagttagaa gaaggtgata agtcatcttt
    17761 aagagcgaaa gcttatgata ttgtattgaa tggttatgaa ataggtggag gaagtgttag
    17821 aatatcaaat tctgatgttc aatcaagaat gtttaaagca cttggtttca cagaggaaag
    17881 agctaatgaa aagtttggtt atttattaga agcatttaaa tatggtactc ctcctcatgc
    17941 tggtctagct tttggtcttg atagacttgt tatgttactt gcaggaactg ataatataag
    18001 agaagttatt gcattcccta aaaatcaaaa tgctgtttgc cctatgacaa atgctcctac
    18061 attggcggaa gatgagcaat tagaagaatt aagtataaaa gttgatataa aagataatga
    18121 ataatatgta gttgcaagaa actaaaatgt aaaaagtctg gatataaagt atatttatat
    18181 tcagactttt tttattagaa ttattttata ttttttctct atatattttc ataaattatc
    18241 cttgtattct cagccaatat aattaaaata ctatgtttaa aaattttaca taaacttgat
    18301 tgttttagaa attacttctg taatgagtac acgatcttaa ttaaagaata tataacaaat
    18361 ttgaaataag tctaatatat gacttaatag attaaattaa aataataaat ttggactatt
    18421 tatctattta taacttaaat tatatcaaat tgataacaaa ctagatatta tacttttttg
    18481 tagaatagaa ttacaattat ataaagaaaa attctattaa tagtgaaaaa aaagtagaaa
    18541 aaagtagaaa ttattctttt ataaagaaag ggagggataa tattgcaaga gagagaagaa
    18601 ttagttttaa atccagttcc aaaagaggaa agagttggat ggttagctcc attgtttaat
    18661 atgcttggtt ctaacatagc tatatctgaa ctaatggttg ggggaacttt aattttagga
    18721 atgactcttt ctaatatgat tattacatca attataggga acttaatatt agttgcaatc
    18781 attatgatac aaggttatat aggttacaaa gaagggttaa atacgtatgt attagctaag
    18841 ggggcatttg gagagatagg aggaaagtat cttatatctc tattacttgg tataactagt
    18901 tttggatggt ttggtgtaca agcaggggtt gcaggactat cagtacaaaa gatattccca
    18961 agtgtaaacc taacattagt tacagttata cttggattat ttatggttgt ttttgcactg
    19021 tatggcttta aagctatggc taaatttaat tacctagtta taccaccact tatgatatta
    19081 atggtgtggg gagtttttaa agctttttct acttatggag ttgaagctat ttataattat
    19141 actcctcaaa caactatgag tatggttgaa ggtcttaata ttgtagtagg tcttgttata
    19201 gttggtgcaa ttatatcacc tgaccagtta agatatacga gacgagtaaa agatatttgg
    19261 attatcagtt ttttaggtct agggattatt tcattattcc aacaagttgc agctggtgta
    19321 atgtctatgg gagcacctac ttgggatata acagaagtat tggctaattt aggttttgga
    19381 tgggtagcgt ttgttatttt aatacttgca tcttggtcaa caaacgtatc aaatgcttat
    19441 tctggtggat tagcattaaa aactattttt ccaaatgtaa aaagaaatgt tttgacttta
    19501 gttgcaggtc taataggtac aataatagca gctactggta taatatttaa atttcagtca
    19561 tttttatctt tcttgggaat cgcagttcct gcaatagcag gaattatgtg gtgtgagtat
    19621 tattttatac aaggaagaac ttataagcat agagaaggaa taaattggat tgcagtaata
    19681 agctggttaa taggttttgc agcgtcgtat tatagttcaa aaataaattt cttaatacct
    19741 ccgataaatg gaattgtagt gagtatggtt atttattata tattaatgaa atgttttgga
    19801 atcaaagata aataaagggg gcaattacat gggtcgtaag gtgaaaatag gtataattca
    19861 acaacacagt gtacttggag atgttaaaaa aaatatagaa acagcagtag agatgataga
    19921 tgacttagga aaacatgggg cagatataat ttgtttacca gaactatttg ctacaggata
    19981 taatttagag tctttaggtg gagttaaaac attagaatta ataagagaac ataataagta
    20041 catagaggaa tcaatgtcag aagctgctaa aagaaataat gtatacctga tatctccata
    20101 tggaacctta gaaaaagggt ctacacatgt ttataattca gcagttatat ttgatagaaa
    20161 aggtaagatt atgggagaat actgtaaaaa tcatctgtgg tcattagaag cagtatactt
    20221 taaaggaggg gaaaaagtag aggtatatga tgctgatttt ggtagatttg gtgtaatgat
    20281 atgttatgat gcaggttttc cagaagtatc cagagaattg acattaaaag gttctgaaat
    20341 aatatttata ccatctgcat ggagaataca agatgaagat atgtgggatt taaatgtatc
    20401 tcaaagagct ttagagaaca ctgtatatac agtaggtgta aatttagtaa gtaatgactc
    20461 taatttaata ctatttggaa agagtaaaat atgcaatcct agaggtactg taataactca
    20521 attagataca tacagggaaa aatatgtatt atcagagatt gatttagatg aaataaaaaa
    20581 gtatagggaa gatataccct atttgaaaga cagaaaaagt agctataaca tataattcta
    20641 tactataata caagttcaat ataaaatgat aaaaagagga tgtatcaata ttaagattaa
    20701 atttattata ttttgatata tcctctttaa tattatcaac tttgatttaa atatttttaa
    20761 aatagttgat aagaaagttt ttgaacaaca acacagcttt agattcatag ttttcgctaa
    20821 accatgaaag atttaaatat cttttaaatt caatatcttt gatatgtaac aacttaatct
    20881 cagggtcttg agataatccc catgattttc cacatataaa tccaactcct tgaagtgatt
    20941 ttataagagc ataaattgta tatggtgaat cagactcaaa tgctattttg ggtttgaaat
    21001 tagctgattc gcacaggata tcaattacct ctctataatt ctcacccttc gttataacta
    21061 taaagttttc atctgaaact tcgcttagat atacttcatc ctttaatgat aaaggatggt
    21121 ttattgaaac tcctaatagt atttcttcgc atgttaaagt tatgctattt tctgagttta
    21181 gctttgtaaa tgaagaagat atgtacaaat caaaatcact ttttttataa gatgatggca
    21241 aagtatgtga cacattaaaa gtaatattgg gatatagttt tctgaaatta ctcaaaagtg
    21301 atggtaacac attagccgct gcaggagata atatctttac ttctcctgaa ttttctaaag
    21361 aagtgtcttg taactccttt tttgaacttt ctactaaatc taaaatgcta tctactcttt
    21421 ttagaaacaa tcttccatac tcatttaaaa caatatatct tccttttctg tcaaataact
    21481 gaactccaag ttctttttct aaggaagata tagttttgct taaagctggc tgtgctatat
    21541 ttaacttgtg tgatgctttt gttatgtgct ccattctagc aacagtttga aaatacttaa
    21601 gatgcaataa atccatagta taaaatacac ctcttttaat atgacttgag ttatatcaat
    21661 tttataatca actccacatt atacattata atataaagtt tgtataatca actacaatat
    21721 attaaaaagt tatttaaatt gttatttata ttttgtacat aatctaatta aaaaaagtag
    21781 ctttaaatga ttaactaagg aaatgttgtt acaaacttta gttatataaa aaattcattt
    21841 gatgagtaaa gtattaatgt caagtaagaa taaaagctta ttagatagaa aaataatatt
    21901 ttataataat gatgttactt aaattattat gttatactat tttaaatagg aaacatttag
    21961 atactataat tttaggggga gtcaagatga aattaactaa atcaatatca tcaatgctat
    22021 gcttagctct agttttaagc ttatcaccag tagcatatgc aaatgaaata agtagaacaa
    22081 cagtggagaa tactttagta ggtcaggaca gataccaaac tgctgttgaa gtaagcaaaa
    22141 aaggatggag tagtgcaaat gaggctgtag ttgtaaatag tgaatctatt gtagatgcat
    22201 tagctgtaac accatttgct aaattaaaaa atgctcctat attattgaca gaaaaaaata
    22261 atctaaattc acaaactgag aaagaattaa aaagattagg agttaaaaaa gtttatataa
    22321 ttggtctatc tagttctgta tcaaatgatg tgcaaaaaca gttagaatct aataatttga
    22381 ctactgatag agttggtggt agtgatagat accaaacagc tttgagtata gctaaaaaaa
    22441 tagaaggatt aaaagatata tcagaaatag ctgtagtaaa tgggtacaca ggtcttgcag
    22501 atgcagttag tatagcttct gtagctgcta ctaatggaat ggttatactt ccagtatctg
    22561 atgcatctgg tatatctagc tttaaagatt ttatagaatc taagaatata aataaatcat
    22621 acataatagg ctctactaat gctgtatcag ataaaataaa acaaagttta cctaattcag
    22681 aaagaatagg tggagcagat agaaatgaaa ctaatggtaa agtaatagaa aagttttata
    22741 catctaataa attaaacaat gtatttgtgg ctaaggatgg aatgaaaaat caaaatcaac
    22801 ttatagacgc tctagcagta ggagtactgg catcaaaaga aaattctcct gtactaatcg
    22861 taggagaaca attaagtgca acacaaaaga gtgtattttt gaataaaaat gctacctcta
    22921 taactcaagt tggtagtgga ggaaatgaaa atgcatttaa agaattaaaa gatttacagg
    22981 caaatagtaa caataagaga gtaatgtatg taactaatac agataaggta aatataagaa
    23041 atgatgctac aatagaagct tctgttatag gatatctaaa taatggtgat gaagtagaag
    23101 ttttagatgt gttaaaaact ggatgggtaa aaataaaata caatgaaggt attggatatg
    23161 ttagtgggtc ttatttgaca aataataagc ctgataatag taatgaaaat ataaaaataa
    23221 agtatgtaaa agaaaaagat ggtctaaatg ttaggaaagg accaagtaca gaagatgaaa
    23281 aaataggtca cctttcatat ggaagcaaag tagaaacaat agaaatgttt gctactggat
    23341 gggtaaaaat aaagtataat ggtggatatg gttatgtaag taatgattac ttatctgata
    23401 caccagttat ttaattataa gtaacaataa aaaactgctt taatttgtaa agcagttttt
    23461 ttataaaaat ttaagtctaa taactatttc tattttgata ccttaatcct gggatttatt
    23521 attatggata ttatcaacat acaaacactc caaatccagt gtctaattcc aaacttagat
    23581 attaataaat tcagtcctgc tatggtaaat aagcagtatt taattacaat taaaagtgta
    23641 tttatagaaa tccccttcat agaaagtatc ctaaatccaa taatagacat tctaagtcct
    23701 ataaatgcca ataatatacc tgcaatatcc tgaattaagt aatagtattc aaatttcata
    23761 ttcaatcaac tcttctctga gcagtatcaa atacttctaa ctcttcaatt tcatcatctg
    23821 tgtatgtaag catagtaaaa ccagttacac cataaataaa tgaaattata ggtgtaatcc
    23881 aacttaagaa acaatatgga ataaattcta gtgggcttac accaagagtc tgagcacaga
    23941 aaacagcatt tgaattccat ggtattaatg gaccaccaag tgtagctgta tcttctataa
    24001 ttctagatag attttgtggt tttaatttaa attctttgta tattggagac attagagttc
    24061 cgacaaatac agaagtaaac atcattgatg aactaaatgc atttgcaaag tagcttacta
    24121 taaaagtaga cccaaccaat ttagttcttg attttcctat tttagttata agaggttgaa
    24181 gcagtacttc taagaatcca gttttttgga gaataccggc aataacgaaa actacaaata
    24241 ctagtaaaac ggtttcagcc atactcatta ttccaccacg atttaatagt ttgtcggcat
    24301 agacaaatcc agtatctata gtaaatcctg atagcatgta atttaaaaca tcacctattt
    24361 tttctccttc ttgaaatact gctataataa gtcccatgat agctgaactt agtatagata
    24421 taatgggtgg cttttgtagc aataaaagta ataataaaaa tattattgga atcattgcta
    24481 ctaaaccaat atgaaagttt gaatttaata catccttgat ttgatttatt tgaacatagt
    24541 ctatagtatt atttgaatac ttaaatccaa ttactgtata cagaactata catattacgt
    24601 atgcaggtcc tgtggtataa aacatatgct tcatatgtgt aattacatct gtcttacaaa
    24661 ctgctgcagc taagtttgta gaatctgata gaggtgacat cttatctcca aagaaagcac
    24721 cagaaatgac tgcaccagct gttaaaccaa gaggaatacc catactagta ccaatactca
    24781 tcattgctat accagaagtt ccaagagtcc cccaagatgt accagtagca acagaagtta
    24841 atgaacatac gattaatgtt gtaagcagaa aatatttagg ggttattatt gttagtccac
    24901 tatatactac tgttggtatt gtaccagcag ctatccaagc tgctattagt acaccaacag
    24961 aaagtataat taagtttgat tgaaaggcat ctttaccaac ttcaaatcca aaagcttcta
    25021 tttcatcatt agtataacca agtttcatgg ctgcaggaac tactataagc catgaaagta
    25081 aaaacattgt agttatagaa gcattaaata caactatacc aactgatgtt agagctatta
    25141 ttgcaagcat tactaacaag gaatatctaa atgaaggtat ttttctttct gtattcattt
    25201 tcatagtgca aattctcctt aaatattttt agttaattgc attttttatt cttataagag
    25261 cttcttcaag catacttctt ggacaagcta agtttattct ttgataccca cttcctccaa
    25321 tgccaaagct gtttccttga tttagagcaa ctttaccttt ttgtacaagt acactttcta
    25381 gttcctcatc acttaatcca agtgcactaa agtctaccca taataaataa gtaccttctg
    25441 gttttctaac tttaagtttt ggcatatttt catttatata ttttatagca aaatctatat
    25501 tagattctaa atattctaaa aatgattcta gccaagattc accattatta tatgaagctt
    25561 cagttgcaac taagctaaag caattatttc tctttatatc aattctggta aaagcatcat
    25621 ctaacaattt atagtctttt tcatcaggta gtattacata tgatgattga agaccagcta
    25681 tattaaaagt tttagttgga gccatacaag taattgtatt tttttcaaat tctttagaaa
    25741 tagatgccat aggaatatgc ttatgttttt ttaatataat gtcactatgt atttcatcag
    25801 atatgatttt tacattatgc ttaatacaaa tatctcctag tttttttaat tcatcttttg
    25861 tccatactct accaactgga ttatgaggat tacaaagtat gaataatttt acatctttaa
    25921 tcttgttttc aatgtcttca taatccatta tgtagtttcc attttctagt ttctgtaatg
    25981 ggcttataat tagttctcta ttgttatttt ttacaacact attaaaaggg ctgtaaactg
    26041 gttcttgtat cattatttta tcatttgctt ttgtgagttc atttattaaa agacttatag
    26101 ctgggataac acctggacta taaattaacc actcactttt tattttccag ttatgtctcc
    26161 tatctagcca gtttactata gattcattgt aagaatctgg tcttgttgtg tagccataaa
    26221 tctcttgttc tagtctattt tttaaggaat caattataca aggtgcagcc ttaaaatcca
    26281 tgtcagccac ccacatagga agtaaatcat tagttccata ctttttttcc atttctgacc
    26341 atttagatga aaaattattg cttctatcaa caatctcatt aaaattataa ttcattgtaa
    26401 atacctccag taattttaat tttatgttaa taatattaag caaacaacgt gccaatattg
    26461 ataataaaaa atatttattc acaagttaat atttaatatt aagtaatttc agagcataga
    26521 taagataaaa atattaatta tacttaaaac tttgtggaaa aggttatttc taataaattt
    26581 ttaaatatat gaaaatgtaa ttaaataggt taaataggtt taactgttta acttgttaga
    26641 cctatttgta ttttttagaa attctactcc ttttgatgtt ataattgaac ctccacgacc
    26701 aacaagtatg tctacaagcc caaagtcttg tagttctaaa agcatatttc taatctgttg
    26761 ttctgtcaaa aatctatttt cctctaaagc tattttacat aagctttttc tacctattct
    26821 ttcttttaaa tcataagcct tttttaaatt atccaatata aatatgtatt catctagtga
    26881 ccttttaaaa ttatagtcgt atttcatgat gtttttgtct ttgccaatgt tgaattgata
    26941 cttttttata ttatcactta ctttattaca aacggttcta ctataatttg aatctatagt
    27001 gtccaatata tattcaggta aatcacatat ttctataata tcttttccca agtaacagaa
    27061 gtattctcct aagtttctta attctcttac atttccttcc catctataca ttttaaagat
    27121 ttcttttact tcctcactta gaataaaatt acatggaata tcatatttta atgaaccaaa
    27181 aatttcaaat atatcagcag ctctttccct aagtggatgt attttaaggg gaagaacatt
    27241 caacctaaaa tataaatctc ttctaaacat atttttagat acaagttctt ttaaatttct
    27301 attagtagct gcaattattc ttacatcaat atcaatgaca ttattagaac caatacgtcg
    27361 tacttgtttt tcttgtatga ctctaagtaa tttagattga gaatttaaat ccatttctcc
    27421 aatttcgtct aaaaatatag ttccattgtt ggctaattca aataaaccaa ttttcccacc
    27481 ttttttagca ccagtaaaag ccccttcatc atagccaaat aattcacttt gcagtagatt
    27541 ttcttgaaaa gtactacaat ttactgcgac aaaaggacca tcttttctcc tagaagcact
    27601 atgaatggat tgagcaaata attctttacc agtaccactt tcaccaatta taaggataga
    27661 tgaatttgat tgagccattt tattagcaat tttttttgta ttaatagttt gtatactaga
    27721 acctaatatg tcatcaaatg tgtatttact gatattacca gagtttacta gttgtgctct
    27781 taatttagct tgcttttttt ctaattgaga aaactttgtc atctttagta taaatccatc
    27841 aaatacattt aattgtatat gtttaatctc taaatttata tcaatatgat ttattttaat
    27901 caatttctca aaaaatggag ttttattggt caatatgttt tgaaaattga tgtcttttat
    27961 acaatcacca acaaatgagt caatcatttc atttgcattt atagacaaaa tttttctagc
    28021 catatgatta tagaattgaa ttattccatc attatttgtg catataattc catcatcaat
    28081 tatagatagt aacaaatcaa attgtctttc aaacttattt gcatctaaca ataactcacc
    28141 tgtactataa cttgtaggaa ttattttttc tacgtatttt tttattaggt catcttttat
    28201 tagatgtttt aatttggttt ttgtagcaat ttcaacaata caacttaaat ctattattct
    28261 gtattttaaa tctacaactt cacaattttt aaacttaggc aagatttttt cgccaggagt
    28321 taggattaca gcatctgtgg gagtaaactc aatctctgga tagcagggca ggatatttat
    28381 attgtctatt cctaatctat gtattaaaga aattgtttct attgccatat ctttacttaa
    28441 gttatataca taaataattt tatctttttc taatttggat atcatatcaa tactgttctt
    28501 ttcaaatgtc aacttgggaa caatgatttg agcatcatag tgagataatt ttactatttc
    28561 atcgtatttt aaataagcag ataggagtat aagtttttct ttaaaaaact ttaaatttcc
    28621 ctcttcaaat gagtataaat ttatctttag attatcacct aagaattgcc ttatttgatt
    28681 ttcataaatt tctccagcgt ctttttttaa acttacaata gctaattcca tttgtttcat
    28741 tttaacctct catacaaatt tgacttattt tagattacat
//
LOCUS       DACTZW010000048        28762 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.048, whole genome shotgun sequence.
ACCESSION   DACTZW010000048 DACTZW010000000
VERSION     DACTZW010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28762
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.048"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(<1..1352)
                     /locus_tag="JAM15_11315"
     CDS             complement(<1..1352)
                     /locus_tag="JAM15_11315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HAT6798841.1"
                     /translation="MNFRDLFEKAVDFIDEKRKSIVAISLSTLGVIALIIVFFLSSNE
                     FSVGNEANELLKIIEKRQYSIAVDYYTSIEKKFSDSKMERFNKSVSKKINKLLLNSGD
                     KYLDGDISQESFIGLINTVKELNKISIDVDDLLAQADRVREMYKEENTTYDIAINYIS
                     TVSILNGMGSNLDVYKQNIETIKESRDVYDSAVKDQKAYKYYEAIEKYNKVLKEDEKY
                     YSMAQNGKEQCIEEMYDYYISRAEEANTSGDYERALQYIEYLKEDYSDDEKVQSLEKK
                     YKKNLSLYTLTSDDIINVIAKKSGKDKANLSINSLPQMIKNNKYYYAEVYEYDKLINE
                     VLVSAKTKDLYSYKDGKKDYKVDYGDGYFRILEDGSYQFGITKDKAKFVLTNTLDEKE
                     NKYKKIEILDIEKADRYVKSKKSLEELFGKYKNIYYYAVVNKGLFRGKEVYAINIYNE
                     "
     gene            complement(1518..1766)
                     /locus_tag="JAM15_11320"
     CDS             complement(1518..1766)
                     /locus_tag="JAM15_11320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798842.1"
                     /translation="MMICFAMTFALVLINSVMGVHIGLDYYFLMGSVLTVCLTIGIVL
                     CNARKIFDSKAIHKTRTKTVSTNKKQKSHSRDIKRKIS"
     gene            2032..4161
                     /locus_tag="JAM15_11325"
     CDS             2032..4161
                     /locus_tag="JAM15_11325"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HAT6798843.1"
                     /translation="MPNLPSLGSKAPDFKANTTNGPIRLSDYKGNWIVLFSHPGDFTP
                     VCTTEFLCFAKYYDEFKKRNTELIGLSVDSNSSHLAWMYNISLLTGVEIPFPIIEDRD
                     MRIAKLYGMISKPMSDTSTVRSVFIIDNNQILRTILYYPLTTGRNIPEILRIVDALQT
                     SDRDNIVTPANWFPGMPVILPYPKNYKELKNRVNSCNKKYSCMDWYLCFVPDNYNDEE
                     VSKKIDNTCSWKKEHTKNIENECNCEHEHHDYLNKALDCKQEHKTDIKDDCNHEKKHT
                     KNTNKVHNSKQDKFKDKSCDEMNFNYDKDESCDKINSSYNKEDSSYEDFYKHNYKNYD
                     YTSEKNTKKIAMKTLKDSKKLVRPQITDPYNPIVENANCPDINPIVAEYVLGNPTNVD
                     AQLLDAVIFAFAEIDQSGNLFIPYPRFLNQLLALKAEKPSLKVIVAIGGWGAEGFSDA
                     ALTPTSRYNFARQVNQMINEYALDGVDIDWEYPGSSASGIISRPQDRENFTLLLTAIR
                     DVIGDEKWLSVAGTGDRGYINSSAEIDKIAPIIDYFNLMSYDFTAGETGPNGRKHHSN
                     LFESDLSLPGYSADIMVRNLENAGMPSEKILLGIPFYGRLGATITRTYDELRRDYINK
                     NGYEYRFDNTAQVPYLVKDGDFAMAYDDSLSIFLKTQYVLRNCLGGVFSWTSTYDQAN
                     ILARTMSIGINDPEVLKEELEGIYGQF"
     gene            complement(4403..5002)
                     /locus_tag="JAM15_11330"
     CDS             complement(4403..5002)
                     /locus_tag="JAM15_11330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="reverse transcriptase-like protein"
                     /protein_id="HAT6798844.1"
                     /translation="MAKQKFYAVKKGKNIGVYNTWDECKKQVNGFSGAEYKSFSTFQE
                     AKEYIDGSEKLSFQEGKDFIEAYVDGSYEHSVKMYGSGVVILKNNKVIKTYSEKGKEK
                     TLVSMRNVAGEIEASKIAMQYCIDNNVQNLILYFDYEGIEKWCTGVWKTNKEGTIAYK
                     NFYDSIKNKLNVKFTKVKAHSGNKYNEEADKLAKKAIGV"
     gene            complement(5020..8139)
                     /locus_tag="JAM15_11335"
     CDS             complement(5020..8139)
                     /locus_tag="JAM15_11335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HAT6798845.1"
                     /translation="MDNIISVLNDVVFLDIEVSGLDCLNSEILEVGAVKVKDWKIYTY
                     ESLIKNKFEVPIEVFSVCKNLDKNDLEIANEIELVEDRLVNFVEDSFIICHDLSLKKK
                     FFEYHMPKLKNKFIDLIELAVILEPYHKDYSLEYLKNTLTNCNSKVENRALSDAIDII
                     NIVNCLLVKFNNYEKTTLEPLSFKINSYLKKFNLPTWEWSKFLEEANYDLSNNINIKK
                     EYNIFDSKEEKKKERETLKILNEEEKNYEELLKYKTIWENKEGFTYEYRPGQYELTKT
                     IRELFRNSEDEEKIACIEAPTGIGKSVGYLLPAILEARINKKRLLISTDTKELQIQLI
                     NKDIPNVLDSLGLNGKVSYGYIKGKNNYICIDRLEAYIDDYESQNPTKGEILSLIFLK
                     RLVEGGKYGDIEEINYSVFDNFKEISTHLRNVSCDPNMCRPKKCKKDCLYKNRIEELK
                     EEHITVVNHSLLAKWPYKDEKPLENIIVDEAHNLTEKGYDFFSSIINSKSLRYLLQEI
                     YPYEFIQNSSFIYKKYSRNMRKIKAFDKFYNVLKIEREDKQKIARSINLIIEEIDSIL
                     NFGNCNEYNNVSNYNLRWELNLQIDEIVGKLKKDGVDTEISYRAYSEKIKLSCEKIIK
                     NLVSIIIIIYRNIDDDSIDKEADIYKFGKAKTRDLEDIKIIFEIFLEYDEKDDYARIV
                     EIDKNYNDFEFRVVPLKIADLFEENILSQLEKGIFLSATLSLSESMSYFKNTLGIDRV
                     KNVEKIIEPIFDYKNRVSVVGFSDICEYRNSEFPNEMSKIISNISKITEGHTLALFNS
                     KDRQEKTYEILKKYLHSFNLEIYADKKGIRHLNDLNRKCVVLGSKGCFEGVDIPGDGL
                     VCVTLDKLPNLNPKDPLYFTIMKKYGIDYYTINYPQMTIKVKQAMGRILRSKYDYGCF
                     VIFDVGTNISVLKRLEKDLHDCKISKVNSNEFYTYIRRHLNKSRSLILKSVIFDTIKA
                     LNVDAKMDNNDVDKDIIKKDINENIRQRAVKGEVYHIDIIKKDMKVKYFDRNYLINLD
                     IFMREEDKN"
     gene            8360..9184
                     /gene="pdaA"
                     /locus_tag="JAM15_11340"
     CDS             8360..9184
                     /gene="pdaA"
                     /locus_tag="JAM15_11340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HAT6798846.1"
                     /translation="MKKDSLKKYIMIGAFALILFGIASINFKSLDKTKTQISSPTLDT
                     HEYDWYFNPREDGKQPSPIKEADFFKKYGAYYVGNPNEKVIYLSFDAGYESGNTPKLL
                     DTLKKHNAKAQFFVVESYIKSNPELIKRMEKEGHLVCNHSKSHPSMAGITDFEKFKEE
                     ITSVEKAYKDVTGKEMPKYFRPPMGKFSEQSLKYTQDLGYKSIFWSFAYVDWYEKKQP
                     THEFAKNKIYSRTHPGAIVLLHPNSSTNTEILDEVLTHWEKEGYKLKTLDYLNNKK"
     gene            9373..10137
                     /locus_tag="JAM15_11345"
     CDS             9373..10137
                     /locus_tag="JAM15_11345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAT6798847.1"
                     /translation="MTTICVMIDHIFLDTEYRQPTIHKHLAKHIIISQSGNLSVTFDK
                     GESLQCKGIIIDSNVSHTVSSKDNKMLVFLIDDTSILAQNISQHQLLNHSFFVIDNLI
                     VERIQNIYTACQVKGLCQSYIDFSKQAFRLLNLNYHISSITDSRIQWALNHILKSTHI
                     HNEIFFEICAEVKLSKSRFSHLFKEQMGVSLNSYLALSKLRKAYELLLKSGDITSAAM
                     DAGFSSPSHFSASSKKYLGITASELIGKCKIYFIRQ"
     gene            10240..11418
                     /locus_tag="JAM15_11350"
     CDS             10240..11418
                     /locus_tag="JAM15_11350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAT6798848.1"
                     /translation="MKTNKISFNKGLYYLNTNANFNFQLNRIIMWDGGRLEDIQKVSS
                     KIVDSESWKTELMYLAQEAEQDGRTENAIAYYRMSEFFMYDGDPDKISVYKKATTLFY
                     NYYSEYFSNGTVQIFHVPYENITLPVMYAKAQGEVKDVILLHGGNDSYFEEFFFPMLY
                     LASQGFDIYLFEGPGQGGVMRLQGKHFTYQWERPVKTILDYFHLENITIVGASLGGFL
                     APRAAAFEKRIERVVAWSVFPNFLDIIVGSQPIKMQNLLRLLLKLKTKWLVNFIIKQK
                     MKSGDSMVVWGLKHGMYAYEASTPYEYFQKIKYYQIDSIAKNINQDILILGATQDHFI
                     DYRTVGKEIDLLNNVRSLTFRLMTEAEQASNHCNCGNSKLVLDTISNWIMMMKIHDRV
                     "
     gene            complement(11789..12574)
                     /locus_tag="JAM15_11355"
     CDS             complement(11789..12574)
                     /locus_tag="JAM15_11355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAT6798849.1"
                     /translation="MIVKIDNTLEKEFWQYVSHEESLNLFIIGYVENYGFSSQYQDIW
                     SQVEDGNITSIILKNKSTLIIYSFKNNFDIGEMKNHIKDLDVESISGKKCVIDRLISK
                     YKDFYEKLDNKFCVLKEIKEIDFSNMKEYKIENAQEKDIDEIGKLLNRSDYKVSKNYI
                     EERKEHLKEGNVRAYFIRNDDTMISTVSTGMETSFLAMVVSVSTDKRYRGKGLASYMV
                     YNLSKELLLEGKVPCLFYNNDVAGKIYHNIGYKEINEWTILFK"
     gene            13039..13404
                     /locus_tag="JAM15_11360"
     CDS             13039..13404
                     /locus_tag="JAM15_11360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6798850.1"
                     /translation="MKIRAEYTCPLEIVHDIIKGKWKTILIFELRQSNKTFSELQHNI
                     YGINQKMLIQQLKELRDFGIIDKISSAGYPLHVEYFLTNRGKKMLKAVEIMQEIGIEY
                     MLEHGQQEILDNKGICYNK"
     gene            13482..14036
                     /locus_tag="JAM15_11365"
     CDS             13482..14036
                     /locus_tag="JAM15_11365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAT6798851.1"
                     /translation="MSIALILIDIQNDYFKNGKCELFQSEETAENAKKILLFFRKNNL
                     PVIHIQHISTDKTASFFLPNTHGSEINKIVFPLDNEEIIIKHTPDSFFETDLQSILEK
                     KNITNLVICGMMSHMCIDTSVRTAKKLRYDITLISDACTTKNLSWNNIEINANTVHQV
                     FMASLQNSFADVKNTDKFLSNYHK"
     gene            14256..14930
                     /locus_tag="JAM15_11370"
     CDS             14256..14930
                     /locus_tag="JAM15_11370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HAT6798852.1"
                     /translation="MNHHILIQFEYIARIITAGFCGALIGYERKNRLKEAGIRTHFIV
                     ALASALIIIVSKYGFNDIVGTPGIGLDPARVAAQVVSGIGFLGAGLIFIRNQSVSGLT
                     TAAGIWATAGTGLAIGSGLYLVGIVSSIIIVIVQITLHRDRKWMKLPTAEQVSLKISN
                     STDSIEYIEGKFKKSNIEIINMNIKRLDGDWLEVVIYTKLPKGYKKTNLLKLFSDNPL
                     IETLEI"
     regulatory      15285..15381
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(15782..16021)
                     /locus_tag="JAM15_11375"
     CDS             complement(15782..16021)
                     /locus_tag="JAM15_11375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798853.1"
                     /translation="MKCSNCGSVNIEKGILTTGGIYAETIGLKYRGDGKLDKVINKTF
                     PVQSTIYSDLCLDCGEIVRTYIKDNTDRNWCKDEK"
     gene            complement(16166..16975)
                     /locus_tag="JAM15_11380"
     CDS             complement(16166..16975)
                     /locus_tag="JAM15_11380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAT6798854.1"
                     /translation="MKDYYKIGEISKIYGIGRDSLMYYEEIGILRPVRDINGYRMYNI
                     SDIWKLNLIKEFRSLNFPMKKIKEYLDDRSIESTKNILNEELDLIDKKIAEFISHKEN
                     IIKRLSSIESVIQNTKIDEIEVVYIEKRKALELNADIKRDEDFDFLIQKLQKEYEDRF
                     NILGNNNIGSAFSTEAINKGIFNEFKSVFCFLESNEKVYNIVFDEGYYVTLNYTGSNS
                     NNKMYMEKVFKFIEENNYKIIADPIEIYKIDIHETGIVEEFVTEIQVPITK"
     gene            17759..19992
                     /locus_tag="JAM15_11385"
                     /pseudo
     CDS             17759..19992
                     /locus_tag="JAM15_11385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
     gene            20023..20868
                     /locus_tag="JAM15_11390"
     CDS             20023..20868
                     /locus_tag="JAM15_11390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HAT6798855.1"
                     /translation="MFKEIFLRTFPGFLIIRDSNYRIIFINDNLKNLIKSYMQDNPLG
                     MTNIEIAKKLPDNIAKFFTDSHNIQLDWEKNYPYDKISNWILEFKKDTTSYWNVLEYK
                     VDVDEKTYIITMANDITKLYEENKRNLHYSITDPLTGAYNRKYLNDRFDIFIGDYIVL
                     IDLDNFKMINDYEGHNVGDKILCDFVSLLNKELINSTSIIRLGGDEFIVIFSSDVDKN
                     YVYSQLEALRENFLKVFSKYKYLSFSYGVDTVKRNLKLTIVELDKKMYKNKEKNKKKF
                     DKNDY"
     gene            21108..22841
                     /locus_tag="JAM15_11395"
     CDS             21108..22841
                     /locus_tag="JAM15_11395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HAT6798856.1"
                     /translation="MSILLKKAPKLAKHIITSFYINRDINEVLKYLCENVTWIGPGEQ
                     EFLTSFNEIKNYFYAGQDEIPSCDINNDIFETVSEDENRCMVLGRYTVRTKENTQMIL
                     EVNQRCTFEIIEDRGKLLVKHMHISNPYGEMQLDEYFPTKIGTQSYDYLQRLLKEKTE
                     VIEMITNNINGGLKGSNDDSTYSFFYVNEGLPKILGYTYDEFMEMSGGSAVGAVYPPD
                     LPKALEDCERCFAKGPTYSSEYRIRKKDGTLMWVLDSGMKSLNSDGIVKINSIITDIT
                     QLKNIESELKLERERYRIALQNITDIMFEYDIENDTLIKYQRVEIDKKIELENFETKN
                     YSKLLESGKIIHLDDIGKLLEVLHGNLRETIEIRQVNSLTKNEWRWIRVQCSVIYDSD
                     HNPIKTIGVLKDITEDKSKLESLINQAQRDPLTQLYNQRVSQNLIEEYLCSSDSKNND
                     ALLVIDIDDFKTVNDTFGHLEGNEVLVAVSKILLHNTHDKDIVARIGGDEFTIFIKSL
                     TKDLIIKITNDILNDASKIKVKDNHKITLSIGIAFTDDSTKLYKDLFSKADKALYLSK
                     ADGKNCYSTYE"
     gene            complement(23920..24540)
                     /locus_tag="JAM15_11400"
     CDS             complement(23920..24540)
                     /locus_tag="JAM15_11400"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAT6798857.1"
                     /translation="MVYRLMRAVGLRSACRKKKFSYVKCTPEVITENILSRKFSVDKT
                     SQKGLTDVTEFKLTNGTKACLSVILDLGDRSIISYVIGKSNNNNLVFEIFDKAIELYP
                     NAKPVFHSDRGFQYTSKVFKSKLLAQGMIQSMSRVGRCIDKAPMEGFWGILKVEMYYL
                     RKFDTYEQLVKAIDDYIYYYNNFRYQKRLNSISPLEFRKYLSTEIA"
     gene            complement(24781..25080)
                     /locus_tag="JAM15_11405"
     CDS             complement(24781..25080)
                     /locus_tag="JAM15_11405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAT6798858.1"
                     /translation="MESYLKGENSVIKVMEDLNIGKRTFREWMRNYETFGNDGLIKQS
                     RNSYYSKEFKLSDVEAYLNGEGSYDTISKKYKMKSVHPLKAWVKEYNIHKEIKET"
     gene            complement(25343..25516)
                     /locus_tag="JAM15_11410"
     CDS             complement(25343..25516)
                     /locus_tag="JAM15_11410"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798859.1"
                     /translation="MYQGRILDLVKLCELRNYDMKGHREITLFLYRYYLCYFYEDEKK
                     VLEDVLEINKEFK"
     gene            25763..26293
                     /locus_tag="JAM15_11415"
     CDS             25763..26293
                     /locus_tag="JAM15_11415"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798860.1"
                     /translation="MSKKFKTFIMSCLISVSTIGVMGTTSFADGIEGTERFIPKGEGE
                     ISISSENARSSGTSNSPHISSLSMGNQLINGSYRSYPTGTHTISMKVVEKTSPNSGLP
                     NYCMVTLQKYKLGGGTSLGSKKIDLRNVGKTYSASFTKQNSGKYRYVFDNRASTIGNW
                     DYIDWFRCDPLKMYVK"
     gene            26360..27028
                     /locus_tag="JAM15_11420"
     CDS             26360..27028
                     /locus_tag="JAM15_11420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003256507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6798861.1"
                     /translation="MINISLRNISKNYKNKIILENINLDIESSKIYMILGKSGAGKST
                     LLNIIGLLDTQSSGNISIKGKVIKNLNDNDKADIRMKELGFVFQGCFLNQKLKVYENV
                     TIPMYINNLYKNIDLKNRSIELLKIFGLEDKYNSFPNELSGGEQQRVAIARAIANDAS
                     VIVADEPTGNLDKENEQKVMEYFKYLSSVGKSIIMVTHNENLLEYADKVFYLRNGKLE
                     EFIL"
     gene            27025..28293
                     /locus_tag="JAM15_11425"
     CDS             27025..28293
                     /locus_tag="JAM15_11425"
                     /inference="COORDINATES: protein motif:HMM:NF014717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6798862.1"
                     /translation="MILKNYINISIKNIVHNKKNTFKIFFITFFSFILFILTTSLSGS
                     LNNFIKNSILNTIEHRTIMINFSVDQNINIENKINNLLENDSSIIEFYEYKPPIAGDI
                     KNSKELFNNDDNNIISLTSGFEQKMPDIIKGNIFNNNDQNVGIIPKNFDPTGTNQVEF
                     KKESINYLDGEEFLGKTITIEFKNSIDELSGFKYNFKVIGVYDSINNNDFPSDVYIPY
                     DDLKMINEKYNNMIDEHYIDSSDNFKTLIALVDNHKSVKNVVDKLRREGIDAFPKSTV
                     GLLDELYKTIIYIGTIISITIFIISIINISLNNVNDLKKRQSELGMLKSFGYKNRQLK
                     KIIIYESTIINMFSLFIGLVICKLIFLLLNTIVKNYLSIYMSDLKFEINLISISIGIF
                     IMIFSVILSNLKSISYITNLNPIRAIRSKY"
     gene            28310..>28762
                     /locus_tag="JAM15_11430"
     CDS             28310..>28762
                     /locus_tag="JAM15_11430"
                     /inference="COORDINATES: protein motif:HMM:NF014717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAT6798863.1"
                     /translation="MKNIINLSLLSIKRDKSKIKIYIIILTIFITLINILLNTSIILT
                     DSINNIYINVDYEMITTVKYIVNSLITFIIVLTFILINILLKQSINDKFFDIAIYKSV
                     GYKDKYIFQLLFYELFIVTTISYLFSIIPSFIGINAINLIFSKFNIHNS"
BASE COUNT        10562 a         4018 c         3483 g        10699 t
ORIGIN      
        1 ttttcattgt aaatattaat agcataaact tctttgcctc taaataagcc tttatttact
       61 acagcataat aataaatatt tttatatttt ccaaacaatt cttctaaact ctttttactt
      121 tttacatatc tatctgcttt ctctatatct aatatttcaa tctttttata cttattttct
      181 ttttcatcaa gagtattagt taacacaaac ttagctttat cttttgtaat accaaattga
      241 taacttccat cttctaatat tctaaagtat ccatcaccat aatctacttt gtaatctttt
      301 ttaccatctt tatacgaata taaatcttta gtttttgcac ttaccaaaac ttcatttatt
      361 aatttatcat actcatatac ttcagcataa tagtatttat tattttttat catttgtgga
      421 agtgagttta tagatagatt tgccttgtct ttgccacttt ttttagctat tacatttata
      481 atgtcatcag atgttaaggt atacaatgat aaattctttt tatatttttt ttctaaactc
      541 tgtacctttt catcatctga ataatcttct tttaaatact caatatattg taatgctctt
      601 tcataatctc cagaagtatt tgcctcttca gctctactta tatagtaatc atacatttct
      661 tcaatacatt gttctttccc attttgagcc atactgtaat acttttcatc ttcttttaat
      721 actttattat acttttcaat agcttcataa tacttatatg ctttttggtc ttttactgct
      781 gagtcataaa catctctaga ctctttgatt gtttctatat tctgtttgta tacatctagg
      841 ttactaccca taccatttaa tattgaaaca gtacttatgt agttaatggc aatatcataa
      901 gtagtatttt cttctttata catttctcta actctatcag cttgagctaa taagtcatcc
      961 acatctatac ttattttgtt taattctttc acggtattta ttaatccaat aaaactttct
     1021 tgacttatgt ctccatctaa atatttatca ccactattta atagcaattt atttattttt
     1081 ttagaaacag acttattaaa cctttccatt tttgaatcag aaaacttttt ttctatactt
     1141 gtgtagtaat caacagctat agaatactgt cttttctcta taatctttaa caactcatta
     1201 gcttcatttc ctacactaaa ctcgttacta cttaagaaaa atactattat caaagcaatt
     1261 acacctaatg ttgataatga aatcgcaact atagatttcc ttttttcatc aataaaatct
     1321 acagccttct caaataaatc tctaaaattc attgtagttc cctctccatt taataatctt
     1381 tatattttat ggtaaactaa atttcttatt ggttattata tcataattct tgaaaaaaaa
     1441 taaaaacaca agttaaatcg tgtttttatt ttacctatca atcattattt tatacataaa
     1501 tatttccttt acataaatta tgatatcttt ctttttatat ccctagaatg actcttttgt
     1561 tttttattag tactgacagt tttcgttctt gtcttgtgta tagctttgct atcaaatatt
     1621 tttctagcat tgcataaaac aattccaatt gttaaacaaa ctgtaagcac acttcccatc
     1681 aaaaagtaat aatccaatcc tatatgtact cccataactg aatttattaa cactaatgca
     1741 aaagtcattg caaaacatat catcatggag ataactaaaa ttcttagaat ttttttcaat
     1801 ccaatcacct cgtataatca ctaaaattga cactacccct tatccattac tataccaaat
     1861 tagtaaaaaa atagcaatta ctattgtcat ttatattagg aaaatattaa atctttttaa
     1921 taaatatctt tttttgacat aaggattact taacttttaa taaaatagta acactaatat
     1981 gtattaatta atagaataaa ataaatgata atttattgag gggtgattta catgccaaat
     2041 ttgccaagtt tagggtcaaa ggctcctgat tttaaagcca atacaacaaa tggtcctatt
     2101 agactctctg actataaggg taattggatt gttttatttt cacatcctgg tgattttaca
     2161 ccagtttgta ctacagaatt tttatgtttt gctaaatatt atgacgaatt taaaaaaaga
     2221 aatacagaac taattggtct aagtgttgat agtaacagtt cacatttagc ttggatgtat
     2281 aatatttctt tacttacagg tgtagaaatt ccatttccta ttatagaaga tagagatatg
     2341 agaattgcca agttatacgg catgatatca aaaccaatga gtgatacatc aactgttcgc
     2401 tctgtattta ttatagataa taatcaaatt ctaagaacga ttctttatta tccactaact
     2461 acaggaagaa atattccaga aatacttaga atagtagatg cacttcagac tagtgataga
     2521 gataatatag ttactcctgc aaactggttt cctggaatgc cagtgatttt accttatcct
     2581 aaaaactata aggaattaaa aaatagagtt aacagttgta ataagaaata ttcatgtatg
     2641 gactggtact tatgttttgt accagataat tataatgatg aagaagtgag caagaaaatt
     2701 gataatactt gtagctggaa aaaagaacat actaaaaaca ttgaaaatga atgtaactgt
     2761 gaacatgaac atcatgacta cctaaacaaa gctcttgact gtaaacaaga acacaagact
     2821 gatattaaag atgattgcaa tcatgagaaa aaacatacta aaaatactaa caaagttcac
     2881 aactccaaac aagataagtt taaagataag tcttgtgatg aaatgaattt taactatgac
     2941 aaagatgaat cttgcgacaa aataaattct agctataaca aagaagatag tagttatgaa
     3001 gatttctata aacataatta taaaaactac gattatacta gcgaaaaaaa tactaaaaaa
     3061 atagctatga aaactttaaa agattcaaaa aaattagtta gaccacaaat aacagaccca
     3121 tacaatccaa tagttgaaaa tgcaaactgt ccagatataa atccaattgt agcagaatat
     3181 gttcttggaa atccaactaa tgtagatgct caactattag atgcagttat atttgctttt
     3241 gctgagatag accagtctgg aaatttgttt attccttatc ctagattttt aaatcaatta
     3301 cttgctctta aagctgaaaa acctagctta aaagtaattg tagctattgg aggttgggga
     3361 gctgaaggtt tctctgatgc agcattaaca cctacatcta gatataattt tgcaagacag
     3421 gttaaccaaa tgataaatga atatgctttg gatggagtgg acatagactg ggaatatcct
     3481 ggaagtagtg catctggtat aatatcaaga cctcaagata gagaaaactt tacactctta
     3541 ttgactgcta taagagacgt tataggagat gaaaaatggc ttagtgtagc tggaacagga
     3601 gatagaggat atataaattc aagtgctgaa atagataaaa tagctccaat aatagattat
     3661 tttaatctta tgagttatga ttttacagcg ggtgaaacgg gaccaaatgg tagaaagcat
     3721 cactcaaacc tctttgagtc tgacttatct ttaccaggat atagtgctga tataatggtg
     3781 agaaatcttg agaatgctgg aatgccttct gaaaaaatcc ttcttggtat accattttat
     3841 ggaagattag gtgctactat aacaagaact tatgatgagc ttagaaggga ttatataaat
     3901 aaaaatggat atgaatatag atttgataat actgctcaag ttccgtattt agttaaagat
     3961 ggagattttg caatggctta tgatgattct ttatctatat tcctaaaaac tcaatatgtt
     4021 cttagaaatt gtctgggtgg tgtattctca tggacatcaa cttatgacca agcaaatata
     4081 ctggctagaa ccatgtctat tggtataaat gaccctgaag tattaaaaga agaacttgaa
     4141 ggtatttatg ggcaattcta atagaatgta gtaaaatttt atagttatat aaaaagcaga
     4201 ttttattata ttaaataagt tgtatctaat taatactatt attaattgtt tataaattag
     4261 atacttattt tttcataata caatctgctt ttttaatcaa aatttattta attataagtt
     4321 ttttaattac aagttgttta attataaagt gggaatttag atatactctt ataccatgta
     4381 attatgtata aatatttttt tattatacac caatagcttt tttagctaat ttatcagctt
     4441 cctcattata cttatttcca gaatgagctt taacctttgt aaattttaca ttaagcttat
     4501 tcttaatact gtcatagaaa tttttatatg ctatagttcc ttctttattt gttttccaaa
     4561 ctccagtaca ccacttttca atcccttcat agtcaaagta taaaatcaag ttttgaacat
     4621 tattgtcaat acagtactgc attgcaattt tagaagcctc tatctctcca gctacatttc
     4681 tcatacttac taaagttttc tcttttcctt tttcactata agtttttata actttattat
     4741 tttttaaaat cacaacaccc gaaccataca tttttactga atgttcataa cttccatcta
     4801 catatgcttc tataaaatcc ttaccttctt gaaaactcaa tttttctgac ccatcaatat
     4861 attctttagc ttcttgaaaa gtagaaaaac tcttatattc agctcctgag aatccattta
     4921 cttgtttttt acactcatcc catgtattat atacacctat atttttacct tttttcacag
     4981 cataaaactt ttgttttgcc aaatatatca ctcccactct taatttttat cttcttctct
     5041 cataaatata tctaaattta taagatagtt tctatcaaaa tattttactt tcatatcttt
     5101 ttttataata tcaatatggt acacttctcc ttttacagct ctttgtctta tattttcatt
     5161 tatatctttt tttataatat ccttatcaac atcattgtta tccattttag catcaacatt
     5221 caacgctttt atagtatcaa atataacaga ttttagtatt aaacttctag atttatttaa
     5281 atgtcgcctt atataagtat aaaactcatt gctattaacc tttgaaattt tacaatcgtg
     5341 taaatctttc tctaatctct ttaacacact tatattagtt cctacatcaa aaatcacaaa
     5401 acatccatag tcatatttgc ttcttaaaat tctccccata gcttgcttta cctttatggt
     5461 catttgagga taatttatag tatagtagtc tataccatac ttcttcatta tagtaaaata
     5521 caaagggtct tttggattta gattcggaag cttgtctaaa gttacacaaa ccaaaccatc
     5581 ccctggaatg tctacgcctt caaaacatcc ttttgagcca agtactacac attttctatt
     5641 taaatcatta aggtgtctaa tccccttttt atcagcataa atttctaagt taaaactatg
     5701 taagtatttt ttcaatattt cataagtttt ttcttgtcta tctttactat taaaaagagc
     5761 taatgtatga ccttctgtaa tctttgatat attagatata attttactca tttcatttgg
     5821 aaattcagaa tttctgtact cacaaatatc agaaaatcca actacagaga ctctattttt
     5881 ataatcaaaa attggttcta taatcttttc cacattctta actctgtcta ttcctaatgt
     5941 atttttaaaa taagacatac tttcagataa actcaaagtt gctgataaaa atattccttt
     6001 ttctaattga gataaaatat tttcttcaaa taaatctgct atttttaatg gcactactcg
     6061 aaactcaaag tcattataat tcttatcaat ttcaactatc cttgcataat catccttttc
     6121 atcatactct aaaaagattt caaatataat ctttatatcc tctaaatctc ttgtctttgc
     6181 ctttccaaat ttatatatat ctgcttcttt atctatacta tcatcatcaa tattcctata
     6241 aattattatt attattgaaa ctaaattttt tattattttc tcacaactca actttatctt
     6301 ttcactataa gctctataac ttatttcagt atctacacca tcctttttta gttttcccac
     6361 aatttcatct atttgcaaat tcagttccca tcttaaatta taattactta cattattata
     6421 ttcattacaa ttaccaaaat ttaatattga atctatctct tcaataatga gatttatgct
     6481 tctagcaatt ttttgtttat cttctctttc aatttttaat acattataaa atttatcaaa
     6541 agcctttatt tttctcatat ttctactata ttttttatat ataaagctac tattttgaat
     6601 aaactcgtaa ggataaattt cttgtaataa ataccttaaa gactttgaat ttataatgct
     6661 tgaaaagaaa tcatatcctt tttcagtcaa attatgtgct tcatctacta ttatattttc
     6721 taaaggtttt tcatccttat acggccattt agctaatagt gaatgattta ctactgttat
     6781 atgttcttct tttaattctt ctattctgtt tttatataag caatctttct tgcatttttt
     6841 aggtctgcac atatttgggt cacaacttac atttcttaag tgagtactta tttccttgaa
     6901 gttgtcaaac accgaataat ttatttcttc tatatctcca tacttgccac cttcaactaa
     6961 cctcttcaaa aatattaaag ataaaatttc tcctttagta gggttttgag actcataatc
     7021 atctatatat gcttccagtc tatctataca aatatagtta ttttttccct ttatatatcc
     7081 gtaacttact tttccattta gacccaaaga atctaacaca tttggaatat ctttatttat
     7141 taattgtatc tgcaattcct ttgtgtcagt agaaattaat aatctttttt tattaattct
     7201 agcctctaat attgcaggca ataaatatcc tacactttta cctataccag ttggtgcctc
     7261 tatacatgca attttttctt catcttcgct atttctaaac aactctctta ttgttttagt
     7321 aagctcatat tgaccaggtc tatattcata tgtaaatcct tctttattct cccaaatagt
     7381 tttgtatttt aataattctt cataattttt ttcttcttca tttaaaattt ttaaggtttc
     7441 tctttccttc ttcttttctt cttttgaatc aaatatatta tattcttttt ttatatttat
     7501 attatttgat aaatcataat ttgcctcttc taaaaatttg ctccattccc atgttggaag
     7561 attaaatttt ttaagatatg aatttatttt aaaactcaat ggctccaaag tagttttttc
     7621 atagttatta aattttacta aaaggcaatt tacaatattt attatatcaa tagcatctga
     7681 taaagctcta ttttccactt tagaattaca atttgttaaa gtatttttta agtattctaa
     7741 gctataatct ttatgatatg gttctaatat aactgctaat tcaattaaat caataaattt
     7801 gttttttagc tttggcatat gatactcaaa aaactttttt ttcagactta aatcatgaca
     7861 tataatgaaa ctatcttcta caaaatttac aagtctatct tccaccagtt ctatttcatt
     7921 agctatttct aaatcatttt tatctaaatt tttacatact gagaatactt ctataggtac
     7981 ctcaaatttg ttttttatta atgattcata ggtatatatt ttccagtctt taaccttgac
     8041 agctccaact tctaaaattt ctgaatttaa acaatctaat ccactaactt ctatatctaa
     8101 aaaaacaaca tcattcaata cacttattat attatccatt tttatatccc ttcaagttaa
     8161 accagcctaa cttatttaca atcatttctc tttatatttt atcatttata tacactttat
     8221 ttaagataat taatatcaac tttatatctt acagtaaact tctttcattt attatttgta
     8281 tatgtgaata tttttaacta taaatattca aactatatta taagaaatat actttaaatt
     8341 ttaaataaga ggtgaaattg tgaaaaaaga tagcctaaaa aaatacatta tgataggagc
     8401 atttgctcta atactttttg gaattgctag tataaatttt aaatcattag ataaaacaaa
     8461 aactcaaatt tctagtccaa cactcgacac acatgaatat gattggtatt ttaaccctag
     8521 ggaggatggt aaacagccat cacctataaa agaagctgat ttttttaaaa aatacggagc
     8581 ttattatgta ggaaatccca atgaaaaagt tatatatcta tcatttgatg ctggatatga
     8641 aagtggaaac actccaaaat tattagatac gcttaaaaaa cacaatgcta aagctcaatt
     8701 tttcgtagtt gaaagttata taaaaagcaa tccagagtta ataaagcgta tggaaaaaga
     8761 aggacattta gtttgtaatc attcaaaaag ccatccatca atggcaggta ttacagattt
     8821 tgaaaaattc aaagaagaaa ttacaagtgt agaaaaagca tacaaagatg ttactggaaa
     8881 agaaatgcct aagtatttta gacctccaat gggtaaattt agcgaacaat ctttaaaata
     8941 tacacaagat ttaggatata aatcaatatt ttggagtttt gcttatgtag attggtatga
     9001 aaagaaacaa cctactcatg aatttgccaa aaacaaaatt tattcaagaa ctcatcctgg
     9061 tgcaatagtt ttactgcatc caaattcatc aacaaatact gagatattag atgaggttct
     9121 tacacattgg gaaaaagaag gttataaact taaaacactt gattatttaa ataataaaaa
     9181 atagtatcat aaattttaaa aaactctatc atgaattata gtaaaaatat agttatttat
     9241 aaatacttta attctcgata gagtttttta tttttcattg cctaaaatag gatttttaaa
     9301 tacttgtaat cactaagctt tcttgttaaa aactgtataa tatgctaagc tatgaacaag
     9361 gagttgacag ctatgactac catttgtgta atgattgacc atatattttt agatacagag
     9421 tatagacaac caactatcca taaacatctt gcaaaacata ttattatatc acagtctggt
     9481 aacttatctg tgacgtttga taagggcgaa tcattacaat gtaaaggaat tattattgat
     9541 tccaatgtat cgcatacggt gtcaagtaaa gataataaaa tgttggtttt cttgatagat
     9601 gatacaagca tactcgccca aaatattagt caacaccaat tactaaatca ctcttttttc
     9661 gttatagata atcttatagt tgaacgaata caaaatattt atacagcttg tcaggtaaaa
     9721 ggattgtgcc aaagctatat tgatttttca aaacaagctt tccgtctatt gaatttaaat
     9781 tatcatattt cgtctattac agacagtaga atacaatggg cattgaatca tattctaaag
     9841 tccacacaca ttcacaatga aatctttttt gagatatgtg ccgaagtaaa attgtccaaa
     9901 agccggtttt ctcatctttt caaagaacaa atgggagtat cactaaacag ctatttggct
     9961 ttatcaaaac ttcgcaaggc ttatgagtta ttgttaaaaa gtggagatat tacctcagct
    10021 gctatggacg cagggtttag ttcaccgtct catttctcag cttccagcaa aaaatatctt
    10081 ggcattactg caagtgagct tataggaaaa tgtaaaatat attttatccg ccaatagcgt
    10141 ctatttgaaa gtcagtactt ctaatatttg ttacaataaa tgcatagcat taaagattac
    10201 tctttattgc tatgcattat ctttttagga gtgatgacat tgaaaacaaa taaaatttct
    10261 tttaataaag gtctatatta ccttaataca aatgccaatt ttaattttca gttaaacagg
    10321 attattatgt gggatggggg gcgcttggaa gatatacaaa aagtttcctc taaaattgtc
    10381 gatagcgaaa gttggaaaac agaacttatg tatctggcac aagaagctga acaagatgga
    10441 cgcacagaaa atgcaattgc ttactatcgt atgagtgaat tttttatgta tgatggtgac
    10501 cctgataaaa tatcagtcta caaaaaagca actactctat tctacaacta ctactctgaa
    10561 tatttctcaa atggaactgt acaaattttt catgtaccat atgaaaatat caccctacct
    10621 gtaatgtatg caaaagcgca aggcgaggta aaagatgtta tattgctcca cggtggaaat
    10681 gattcttact ttgaagaatt ctttttccca atgctttatc ttgcgtcaca gggatttgat
    10741 atttatcttt ttgagggacc tggtcaaggt ggagtgatgc gtttgcaggg aaaacacttt
    10801 acttatcaat gggaacgtcc cgttaagaca attttagatt attttcattt agagaatata
    10861 actattgtag gtgcttcctt gggaggtttt cttgctccac gagcagcagc cttcgaaaaa
    10921 cgaattgaac gcgtggtagc ttggtctgta ttccccaatt tcttagacat aatagttggt
    10981 tcacaaccaa taaaaatgca aaatctactt agactactgc taaaactcaa aacaaaatgg
    11041 ctagtcaatt ttataataaa gcaaaaaatg aaaagtggcg atagtatggt ggtatggggt
    11101 ttaaaacatg gaatgtacgc atatgaagcg tctacaccct atgaatattt tcagaaaatc
    11161 aagtattatc aaatagattc tattgcaaaa aatataaacc aagacatttt gattttaggt
    11221 gcaacacaag atcattttat tgattataga actgttggta aagagattga tttactcaac
    11281 aatgtccgat cccttacatt taggcttatg acagaagcag aacaagctag taaccactgt
    11341 aactgtggaa atagcaaact ggttttagat acaatttcaa attggattat gatgatgaaa
    11401 atacatgata gagtctaaat attgattttt aaattataca aaatccatct gctagcatat
    11461 ccttattgct ttgttcaaat aatcacttgt taaaaaattg gttcccactt acgaaatact
    11521 acgtttatag aaatgaacta tatcatgtaa gcacacaata tatatgataa taagacccaa
    11581 ttactcaatg taactgggtc tttcttatgt catagatttt ataggactca tgaaatgtaa
    11641 aagagtattt caccgatttc caaagggaac tttacttaga taaggagacc ataaatgcta
    11701 acaaacccat ctactagaca cctttcaagt atttgagcga ttatacaata cacgttaaga
    11761 attacacgaa aatttattat ttttatagct atttaaaaag aattgtccat tcatttatct
    11821 ctttgtatcc tatattatga tatattttac ctgctacatc attattataa aaaagacatg
    11881 gaacttttcc ttccaacaat aattctttac tcaaattgta aaccatataa cttgcaagtc
    11941 cttttcccct atatctttta tctgtactta cagagaccac cattgccaaa aaactagttt
    12001 ccataccagt tgacacagtg ctaatcatag tatcatcatt tctaataaaa tatgctctta
    12061 catttccctc ttttaaatgt tctttccttt cttctatgta atttttactt actttatagt
    12121 ctgacctatt taaaagtttt cctatttcat caatatcttt ttcctgagca ttttctattt
    12181 tatactcctt catgttggaa aaatctattt cttttatttc ttttaataca caaaatttat
    12241 tatctagctt ttcataaaaa tctttgtatt tacttattag tctatctatt acacattttt
    12301 ttccacttat gctttctaca tctaaatctt ttatatgatt cttcatttct cctatatcaa
    12361 aattattttt aaaactataa attataagtg ttgacttatt ttttaatatt atagaggtta
    12421 tatttccatc ttctacctga gaccatatat cttgatattg agagctaaat ccataattct
    12481 caacgtatcc aattatgaat aaatttaaac tttcttcatg tgatacatat tgccaaaatt
    12541 ctttttctaa agtattatct atttttacaa tcaagcagat atcctccttc tatgttaata
    12601 atgatatacc ttataattta tagtatcatt taaaatcatt atattctacc aaatattcta
    12661 aatttttaaa tatctatgca atatgttcgt atttattttt atattctgtt actgcttcac
    12721 tccaagcttc ttctactgaa atacctctct tatttgcaat tttttgtgct aattctatta
    12781 ttttcatagc ttttcttgat atattcatat atattcctcc tctaaattat cataagttat
    12841 tttaaagtta aatttctata gtcatgttat atatttattt acttatatct tactaattat
    12901 ttatgtacta aatatgaact acaatagaag aaatttagaa cttaataaaa cataaaattt
    12961 atatacagtt catatatatt tgtcatatca caagacaagt gatataattt attatcattt
    13021 tactgggggt gatatgctat gaaaataaga gctgaatata catgtcctct tgaaattgta
    13081 catgacataa tcaaaggaaa atggaaaact atccttatat ttgaattaag acaatctaat
    13141 aaaacatttt ctgaattgca acataatatt tatggaataa atcaaaaaat gttgattcaa
    13201 caattaaaag agttacgtga ttttgggatt attgataaaa taagttctgc tggatatcca
    13261 ttacatgttg aatattttct tactaatcgt ggtaaaaaaa tgttaaaagc agtggaaata
    13321 atgcaagaaa taggaatcga atatatgctt gaacatggtc aacaagaaat tctagataat
    13381 aaaggaattt gctacaataa gtaatcctat acataccaaa aagtaagtaa tttacatttt
    13441 ttacaatagt attataataa aagtaaatag gaggtataat catgtctata gctttaatat
    13501 tgattgatat tcaaaatgat tattttaaaa atggaaaatg tgaattattt caatcagaag
    13561 aaactgctga aaatgctaaa aaaatactac tgttttttag aaaaaacaat ttaccagtta
    13621 ttcatataca gcatatatca acagataaaa cagcttcttt ttttcttcct aatactcatg
    13681 gttcagaaat aaataaaatt gtttttccac tagataatga agaaattata attaaacaca
    13741 caccagatag tttctttgaa acagatttgc aaagtatcct tgagaaaaaa aatattacta
    13801 atctagtaat ctgtggaatg atgagccata tgtgtattga tacaagtgta agaacagcaa
    13861 agaaacttcg atacgacata actctaataa gcgatgcatg tacaacgaag aatttatctt
    13921 ggaataatat agaaattaat gcaaatactg tacatcaagt attcatggca tcactacaga
    13981 acagttttgc agatgtaaaa aacacagata aatttttatc taactatcac aaataaaaac
    14041 atacactatg ttaaaagagc aagtttgatt tatttaagct tgctctttaa tcatttaaaa
    14101 ttagatgctt tctatcattt ttatatacat aatatacgtt tatacatttt atattcatat
    14161 ataactatta tataaatttt aaactttact atattcacat aaaaaatgta gtattatagt
    14221 atatataata ttatatagaa gggggtgcta gataaatgaa ccatcatata ttgattcaat
    14281 ttgaatatat agcaagaatc attactgctg gtttctgtgg ggctttaatt ggatatgaga
    14341 gaaagaatag actaaaagaa gctggaatac gcactcattt tatagtggca ttagcttcag
    14401 cacttataat cattgtttcc aagtatggat ttaatgatat agtgggtact ccaggtattg
    14461 gtctagaccc agcccgcgtt gcagcacaag ttgtcagtgg tataggtttt ttaggtgctg
    14521 gattaatatt tattagaaat caatcagtaa gtggtcttac tacagctgct ggtatatggg
    14581 caacagccgg tacaggtctt gccattggct ctggattata cttagttggt attgtttcaa
    14641 gtatcattat tgttattgta cagataacac ttcatagaga taggaagtgg atgaaactcc
    14701 ctacagcaga gcaagtttct cttaaaattt ctaacagcac tgattccata gaatatattg
    14761 aaggtaaatt taaaaaatct aatattgaaa ttataaacat gaatattaaa cgccttgatg
    14821 gggattggtt agaagtagtt atatatacta agttacctaa aggatataaa aaaacaaatt
    14881 tattaaaatt atttagcgat aatcctctta tagaaacttt agaaatataa tataaaaatt
    14941 gaagcttaaa aataataata tatttaatca aggtcaatat ataaataatt acgggatgag
    15001 tctatataaa attcatccct tgttttttgc cattcatata tattttttca agatattttt
    15061 gttcatctat tatctagcca agtaactctt gtgaactaaa ctttttaata caaaaacttc
    15121 aatacaaaac taaatataat ttttattaaa tattctacat gtatagtttg tttcttgagt
    15181 gaaaaataga tttcatattg ttaagatact gttaaatatt tcaattttct gacaagtatg
    15241 ttgaacaata acttatccta gtgtattatt ttagttgtag aataaaacta aatcggcaaa
    15301 actagagaaa tttagtgacg caaagctata gggactaacg cttataaaat aaactatgag
    15361 ttatgtcagc cagttgccaa aaagatattg ttctttttgt tttatgaaag ttttttaggg
    15421 ggatagtaat atatatgttt agagatgaaa tggataaatg tacacacatg ttaactgctt
    15481 atattagtag tttatatgat tattgtgatt ttatagatac acagctagat gattttatac
    15541 tagagtacgg agaaaatgta gtagaatctt gtttacatca agtgatggta ttggtaagta
    15601 agtataatta aatagaaatt gttttctaga gaaccctttt tagttttatc tacatttaaa
    15661 aatgttatta tattaaaaaa ctaatctccc ctatatgcaa agttttcttc catataacaa
    15721 tttcttccca tttatacttt ttcacttgta tctttaataa aattcaactt caaatattat
    15781 tctatttctc atctttacac caattcctat cagtattatc ctttatatag gttctaacta
    15841 tttcgccaca atctaaacat aaatctgaat atatagtaga ttgtactgga aaagttttat
    15901 ttataacttt atctaatttt ccatctcctc tatattttaa tccaatagtt tcagcatata
    15961 tgccaccagt tgttaaaatt cccttttcaa tatttacact tccacaatta gaacatttca
    16021 catttataac cccctaaaca attatttttt catgctatct tataatttaa aatataattt
    16081 gctaccgatt ttataacaca gtagcaaatc ggtggcaaat caacattttt tcattctatt
    16141 taccatctaa tccattgaaa tatggctatt tagttatagg aacttgaatt tccgttacaa
    16201 actcttctac aattccagtc tcatgtatat ctatcttata gatttctata gggtcagcaa
    16261 ttatcttata attattttct tctataaatt taaacacctt ctccatatac atcttattat
    16321 tagaattact cccagtataa tttaaagtta cataatatcc ttcatcaaaa actatattat
    16381 atactttctc attactttcc agaaaacaaa atacagattt aaactcatta aatatacctt
    16441 tattaattgc ttcagtagaa aaggcagaac caatattgtt gtttccaagt atattaaatc
    16501 tatcttcata ttctttctga agtttttgaa ttaaaaaatc gaagtcttca tccctcttta
    16561 tatcagcatt taattctaaa gcttttcttt tttctatata tacaacctct atctcatcta
    16621 tttttgtatt ttgaattaca ctttcaatcg aactcaatct ttttataata ttttccttat
    16681 ggcttataaa ttcagctatt tttttatcaa ttaaatcgag ttcttcattt aaaatatttt
    16741 tcgtagactc tatacttctg tcatctaggt attcttttat tttcttcatt ggaaagttca
    16801 agcttctaaa ttcttttatt aaatttaatt tccatatatc tgatatatta tacattctat
    16861 atccatttat atctctaact ggtcttagaa tgcctatttc ttcataatac attaatgaat
    16921 ctctacctat tccatatatt ttagatatct ctcctatttt atagtaatct ttcatttata
    16981 taataaactc ctccgaaatc ctatttttat tttaaatcaa cattattact ctataatact
    17041 ataatattag aatatactaa aaaaatcttt aaaacaagga taggaaaata aacatcctaa
    17101 taattaatta ttaaaatatt tttatattgt aatgttaggt atagtattta taacttcaac
    17161 ttttttataa atatatttta gttttatata gttttatgtt tacagctatt atatccatct
    17221 ctatgtaata tttttcatat taaaactgat ttctatagat taatagttta taaatttagt
    17281 aaatgaatat ttattatagt ctttaacaaa aaatacaaga ataaacttaa ttttaataac
    17341 taaaattaat tatgcaaaat tattaatgtg gtattaaatt atgtataaaa agttaattat
    17401 gaataaaata attatgcctt tgaaaaatca ttaaacttaa aattaattat aaaaaaactc
    17461 taccttacta actatacagc tcacaatcta tctatttatg aaaaaatatg atataattgc
    17521 attcaaaaag gaaatctttc aatatactat aatttaagca ttaactaatt ttatctaata
    17581 ttattactaa actaaaaaat atttgtattt gtagcattgg agcaaataac ttaatgtata
    17641 ttcattttaa atacttattt aaaatttagc atttaaatta tttacaaatt aacatttaaa
    17701 tacttctagc ataaatacag ttgtcatcaa aatttaaagt atcttatgga ggaataccat
    17761 gcaaaatcat aattatataa aaatgttaaa taaaaaggta gaagtattat ctaaggaatt
    17821 agatagtaga aattttaaat taaaaacctt aaatgaaata gatttttttc taaaatacca
    17881 aacagagaat ttatgtacca atatattgat gactgtattt cgaaaaatat acatatagga
    17941 atcatgttat taaatatcga taactttaaa ctatttaatg atatatatgg atatctagta
    18001 ggagaaaatt tattaattac tctaactcaa aacctattgc actttattcc agaatcaaag
    18061 ggaatagtcg cttatttaaa aggagaaggt tttttaattg tacttccaaa tgtatcaaat
    18121 aaagagttaa ataatatggg tgcaactatt atagagagcg cccgagaatt aaaaataaga
    18181 cttcctaatg aaaaagaaat atactccaat gttacattta gtatcggcag cactatctgg
    18241 aatggtgaac caaacatgac tactttgatg cttttcaacc aagtatatag ttctttaaaa
    18301 aaggctaaaa gtgaaggtaa aaatagatac attctatttg attttaaaga taatagtttt
    18361 tacaataaat tagaaaatga taaggagttc ttatcagaaa tatcacatgt tctacaaact
    18421 aaacaaattg aagtatttta ccaaccactt tataatataa aaaataatac tatagttgga
    18481 tgtgaggcac ttgcaagatg gagacaccct attaaaggac ttcttactcc agataaattt
    18541 attcctttat ttgaacagtt tggtctgata acggaattag atttgcattt atttgaagag
    18601 aactgtaaaa atataagaag atggattgat aacaatgatg tttttgttcc aatttgttgt
    18661 aacttttctc gtcttcattt ttttaaccct aattttccaa gtatgctaaa aggtattact
    18721 gaaaagtaca gcgtctctac atcaaatttt agcattgaaa taacagaaaa tatattaata
    18781 gaaaatacaa atacaattat tcaacaacta gctgaacttc gttcttatgg tttttctgta
    18841 tcaatggacg attttggttc tggatattca tcttttggta tgttgcaaaa tctacctttt
    18901 gatataatca aaattgatag gatattttta tctcataatt taaatgattt taaaaataca
    18961 accattttgt actctataat aaacattgca agagctcttg ggatgcttac agtatgtgaa
    19021 ggtgttgaaa cagaacaaca tgtagaattt attaaaagta taaattgtga tatcgcccaa
    19081 ggttattatt atgcaaaacc catggagtgc aaagaatttg aaaaattact atctaaagag
    19141 aataattcag agaaaatgtt tataaaatat tctgatatag gaaaatcttt aatagagaag
    19201 atatttgatg gattttttat tatgcaagat atgaaaaaac taagagctaa tgtcactgaa
    19261 gacattcaat ggtttgattt ttacaacaaa actgaaatta catcttttcc taaagtaata
    19321 gaacattttg aaaaacatat taaaggtaaa aaattttcta ttctttacaa aagtataacc
    19381 ccacataata ctgaatcaga ttcattatta attagtggag aagccgtttt atcagatgaa
    19441 gcttctgaac atcaaaaata tagcaatttc tactttagtg caaattgtat aatttcagaa
    19501 aataaattac tcttagcaaa attacatttg gatttaatta aaactgctgg ctatataaat
    19561 gaatttgaat catattcaat acctaaaatg acaaatacac atcttgatga aagtaatatt
    19621 ttatcacaat tttattcaat gttgcctgta ggtataattc gctacgattt atttggtgat
    19681 atgattatta cttatatgaa tgaagaaatg tttgatatta taggttatac aaaagaacag
    19741 ttttttggtg agatgggcgg aaatttaaga gcaattgttc atccagatga tttagacttt
    19801 gtttataaaa aaagtttgga tatgattgac acaaataaaa ttgaaccatt tttatataga
    19861 ttcataaaac gagatggtca aattgtcaca gttatgtata cacaatgtaa cctttctgca
    19921 attgatggaa ggtcgattgc ccaaggtatg tatgtagatg taaataaaat aaaaaattta
    19981 acaaaaatct agtacaaagt attttatttt ggagaaatta atatgtttaa agaaattttt
    20041 ttaagaactt ttccaggatt tctaattata agagattcta actacagaat tatatttata
    20101 aatgataatt taaaaaattt aattaaaagt tatatgcaag ataatccact tggaatgact
    20161 aatatagaaa tagctaagaa actccctgat aatattgcta aattttttac ggattctcac
    20221 aatattcaat tagattggga aaaaaattat ccttatgata aaatttcaaa ttggatttta
    20281 gagtttaaaa aagatactac aagctattgg aatgttttag aatacaaagt agatgttgat
    20341 gaaaaaacct acataattac tatggccaat gatataacaa aactctatga agaaaataag
    20401 agaaatcttc actactcaat tactgaccca ttaactggag catataatag aaaatattta
    20461 aatgatagat ttgacatatt tataggagat tatattgtac taattgactt agataatttc
    20521 aaaatgataa atgactatga aggtcataat gtaggagaca agattttatg tgattttgtt
    20581 tcacttttaa ataaagaatt aataaattct acttctatta taagattagg aggagatgaa
    20641 tttattgtta tattctctag tgatgttgac aaaaattatg tttattcaca actagaagcc
    20701 ttaagagaaa attttttaaa agtattctct aagtataagt atctttcatt tagttatggt
    20761 gttgatacag taaaaagaaa tttaaaattg acaatagttg aattggataa aaaaatgtat
    20821 aaaaacaagg agaaaaacaa gaaaaaattt gataaaaatg attattaaca ttgttatttt
    20881 aaaataaatt aaaattatct ttcttttttt aaacttgtac attagtttat aaatatgtat
    20941 ctatacaaga tattgacatt aagtactgaa tcatatattg tttcagttct tttttgttaa
    21001 aattaactta tttaacaaag atatcatagt ttaacaaagc ttttaattta aatatattga
    21061 tgtataatat aattaaaata taatagcaaa aagaaaggag gaatatcatg agcatactcc
    21121 taaaaaaagc acccaaatta gcaaaacata ttataacaag tttttatata aatcgagata
    21181 tcaatgaagt attaaaatac ctttgtgaaa atgttacatg gattggacca ggagaacagg
    21241 aatttctcac ttcttttaat gaaataaaaa attattttta tgcaggtcaa gatgaaattc
    21301 cttcttgtga tataaataat gatatatttg aaactgtaag tgaagatgag aatagatgta
    21361 tggtattagg aagatatact gttcgaacta aagaaaatac tcaaatgatt ttagaggtaa
    21421 atcaacgttg tacatttgag ataattgagg atagaggaaa attattagta aagcacatgc
    21481 acatatcaaa cccttatggt gaaatgcaac ttgatgaata ctttcccact aaaattggaa
    21541 ctcaaagtta tgattatttg caaagattac taaaggaaaa aacagaagtt attgaaatga
    21601 ttacaaataa tatcaatggt ggcttaaaag gtagcaatga tgatagtaca tactcatttt
    21661 tctatgtcaa tgaaggattg cccaaaatat taggatacac atatgatgag ttcatggaaa
    21721 tgagtggtgg ttcagcagtg ggtgctgtat atccaccaga cttacctaaa gcactagaag
    21781 attgtgaacg atgttttgca aaaggaccta catattcatc tgaatataga atccgaaaaa
    21841 aagatggaac attaatgtgg gtattagatt ctggaatgaa atcgttaaat agtgatggca
    21901 tagtaaaaat taatagtatt attactgaca taacccaact aaaaaacata gaatctgaac
    21961 taaaattaga aagagagcga tatcgtattg ctttgcaaaa tattacagat atcatgtttg
    22021 agtatgatat tgaaaacgat acccttataa aatatcaacg tgtagaaatt gacaaaaaaa
    22081 ttgaattaga aaattttgaa acaaaaaatt actccaaact attagaatct ggtaaaatta
    22141 ttcaccttga tgatattgga aaactactag aagtacttca tggaaatctt cgtgaaacaa
    22201 ttgagataag acaagtaaat tcattaacta aaaatgaatg gagatggatt cgtgttcaat
    22261 gttcagttat atatgatagt gaccataacc ctatcaaaac aataggcgtt ttaaaagaca
    22321 taactgaaga taaatctaaa ttagaaagtt taattaatca ggctcaacgt gacccactaa
    22381 cacaattgta taatcaaaga gtatcacaaa atcttattga agagtatcta tgtagttctg
    22441 attccaaaaa taatgatgct ctattagtta ttgatattga tgattttaaa actgtaaatg
    22501 atacttttgg gcatttagag ggaaatgaag ttttagttgc tgtatcaaaa atactattac
    22561 ataacacaca tgataaagac atagttgctc gaattggtgg agatgaattt acaatattta
    22621 taaaatcatt aacaaaggat ttaataataa aaattactaa tgatatttta aatgatgcaa
    22681 gtaaaataaa agtaaaggac aatcataaaa taacattaag tattggtatt gccttcactg
    22741 atgattcaac taaattatat aaagatttat tttctaaagc tgataaagct ctttatctat
    22801 caaaagcaga tggcaaaaat tgttatagta catacgaatg ataaagctat ttatacgacc
    22861 aagaatgaac ctttaaattt aatttcatag tctaacaatc aaagagttga agctaatctt
    22921 atagctagtc aactagttcc tagaaaaaat ttagacaata tatttattga tactgctcat
    22981 ttttctaaag agcaaattta tataaaaaat taaactttta tgtacataca gatactaatg
    23041 ataaacagtt atcattagta tcttctatct taaaacaaaa tgataattta tctatataaa
    23101 aaagtgcttt gttgacagag ttcacttttt tatataggta cagaatttaa gtataaatac
    23161 atgttttatt ctatacattt tagttaatgt aaaatttctt gattgtactc tctaactttt
    23221 caacattata ctatttacat accacttagt taatataaaa ccttatatgg tagttgtaca
    23281 agggcaagac aatgacaaat ttacatacca cttagttaat ataaaactaa agtttggagg
    23341 ttttgctatg atatattttt attcatttac ataccactta gttaatataa aacccccaaa
    23401 taaactgggc attttcaata cttacacatg tgcaactctc ttaaatttgc agtgaaccat
    23461 gagtagtgca aatgataaag cttatcacat gccctcaaca ccttatattt caagcgttaa
    23521 accctacttt gtaacaaata tcgctcactg caaaactatt tacattttta ttatatcata
    23581 aatatattat ttttgaatat ctgtaccaat ttgtggtata ataaaaacaa gaagaactac
    23641 aatctattta gacgtagatt gaagttcaaa tactaatgtt tattcttttt gaacttgatt
    23701 tttagttcaa aactaaagtc actcctgcct gaactatacc cgctgtttta tacagttaaa
    23761 acatgtaaaa gtagttataa agtactagtg taactcatta gtactctttt tattatattt
    23821 atataattaa tatctatatt ttaaagttta ctatctaaaa aagatcacgt caaataaaac
    23881 cctagatatt taaatttttt tagaactact taaaataaat tatgctatct ctgtacttaa
    23941 atatttccta aattcaagtg gagatataga atttaatctc ttttgatatc taaaattatt
    24001 atagtagtat atataatcat ctattgcttt aactaattgt tcatatgtat caaatttcct
    24061 taaatagtac atttctacct ttaaaatccc ccaaaatcct tccataggag ccttgtcaat
    24121 acaacgacca actcttgaca tactttgtat cataccttgt gctaaaagtt tcgatttaaa
    24181 caccttacta gtatactgaa aacctctatc actatgaaaa acaggttttg catttggata
    24241 tagttctatt gctttatcaa aaatttcgaa taccaagtta ttattattcg attttccaat
    24301 aacatatgaa attatacttc tatcgcctaa atctagaatt acacttaaac aggccttcgt
    24361 cccattggtt aatttaaatt cagttacatc tgttaaccct ttttgagagg ttttatctac
    24421 actaaatttt ctacttaata tattttcagt gattacttct ggtgtacatt taacataact
    24481 aaatttcttt tttctacaag cagaccttaa gcctacagct ctcattaatc tgtacactat
    24541 cttgtgattg acattaagtt tatactctct gtttaactaa agagtcatcc ttaaggaggc
    24601 aaaaactcca ttcttttctt catatatctt agttatcaaa gttgataatt taatgttttc
    24661 aagttctaaa ttgcttttat ctcgattgag caatttatag tatccagaac gattcacttg
    24721 agtaatttca cataatttga taagcgaagc tttttttcat tgaataatga ttgaattatt
    24781 ttatgtttct tttatctcct tatgaatatt atactcttta acccaagctt ttaggggatg
    24841 aacagatttc attttatatt tttttgagat tgtgtcataa gaaccttctc cgtttagata
    24901 agcctctaca tcactcaact taaattcttt agaataatat gagttacgac tttgtttaat
    24961 taagccatca tttccaaaag tttcataatt cctcatccac tctctgaaag tacgttttcc
    25021 aatatttaag tcctccatta cttttattac tgaattttca ccttttaaat atgattcaat
    25081 tgctttgatt ttttgctatg atgatatttt agttttagac agttttacat gttttaactg
    25141 tctcctaaga gaggtatagt tcaggaccag atgaatttat atttaatata ttgaaataac
    25201 ttaattttta tatgcaaaaa cgtagctttt ttagtttttt taatttctaa tagctctata
    25261 agcgtttcat ttttgtattt atattgtttg tcctttgatt taaatgcctt ttttgcacta
    25321 cctgttgctc gtataatctc tctcatttaa attctttatt aatctctaaa acatcttcta
    25381 aaaccttctt ctcatcctca taaaaataac ataaataata tctatacaaa aacaatgtta
    25441 tttctctatg acctttcata tcataatttc ttaactcaca taattttact aaatctaata
    25501 ttcttccttg atacaatgaa cgttctctat gtatataaac tactttttta ggtctacctt
    25561 ttttctgtgt tctattctcg tctaaatcag gtaaaaactc tctttgtaaa gcctagttta
    25621 caataatatc caaattgctt catttaacga ctggtttgcg cataaagata tcttttttga
    25681 ggtacagtat gatatcctat taaagggaat ttataccaat ttaaaagtta aatactaata
    25741 tataatacaa ggaggtaaat ttatgtctaa aaaatttaaa acatttatta tgtcttgttt
    25801 aatttctgta tcaactatag gagttatggg tactacatca tttgcagatg gtatagaagg
    25861 tacagaaaga tttataccta aaggtgaggg agaaattagc atatcttcag aaaatgcaag
    25921 atcaagtggg acttcaaaca gtcctcatat atcatcatta agcatgggaa atcagttaat
    25981 aaatggtagt tatagatctt atcctactgg aacacacaca ataagtatga aagtagtaga
    26041 aaaaacttca ccaaattcag gcttaccaaa ttattgtatg gttactttac aaaaatataa
    26101 attaggtgga ggaacttctc taggtagcaa aaaaattgat ttacgtaatg ttggaaaaac
    26161 atattcagct tcttttacaa agcaaaattc gggaaaatat agatacgtat ttgataatag
    26221 agctagtaca ataggaaatt gggattatat agattggttt agatgtgatc ctttgaaaat
    26281 gtatgttaaa taatacaaaa ctaaaatatg caactataat aatttatagt tgcatatttt
    26341 ttaaataagg agatagaaaa tgataaacat atcattaaga aatataagta aaaattataa
    26401 aaacaaaatt attttggaga atattaattt agatatagaa agttctaaga tttatatgat
    26461 tttaggaaag tctggagcag gtaaatcaac attgttgaat ataattggat tgctagatac
    26521 acaaagttct ggaaatatat ctataaaagg taaagttatt aaaaacttaa atgataatga
    26581 taaagcagat atacgtatga aagagttagg ctttgtattt caaggatgtt ttttaaatca
    26641 aaagttaaaa gtatatgaaa atgtgactat tccaatgtat ataaataacc tatacaaaaa
    26701 tatagactta aaaaataggt ctatagaatt gcttaaaatc tttgggttag aagataaata
    26761 caatagtttt ccaaatgaac tttcaggtgg agagcaacaa agagtagcca tagcgcgtgc
    26821 aatagctaat gatgcttcag taatagttgc agatgaacct actggaaatt tagataaaga
    26881 aaacgagcaa aaagttatgg agtatttcaa atacttatca agtgtgggta aatctattat
    26941 aatggttact cataatgaaa atttgttgga gtatgcagat aaggtttttt atttaagaaa
    27001 tggtaagttg gaggaattta tattatgata ttaaaaaact atataaatat ctcgataaaa
    27061 aatatagtac ataataaaaa aaatacgttt aagattttct ttattacttt tttttcattt
    27121 atattattta ttttaactac atcactatca ggttctttaa acaatttcat aaaaaattct
    27181 atattaaata ctattgaaca tagaacaata atgataaatt ttagtgttga tcaaaatata
    27241 aatattgaaa ataaaataaa taatctatta gaaaatgata gttcaataat tgaattttat
    27301 gaatataaac cgccaattgc aggagatata aaaaactcta aagaactttt taataatgat
    27361 gataataata ttatatcttt aacatctgga tttgaacaaa aaatgccaga tataattaaa
    27421 ggaaatattt ttaataataa tgaccaaaat gttggtataa tacctaaaaa tttcgatcca
    27481 actggtacta atcaagtaga atttaaaaaa gaaagtataa attatttaga cggagaagaa
    27541 tttttaggaa aaactataac tatagaattt aaaaactcaa tagatgaatt atcaggtttt
    27601 aagtataatt tcaaagtaat aggagtttat gactcaataa ataataacga ttttccaagt
    27661 gatgtgtata taccttatga tgacttaaaa atgattaatg aaaagtacaa caatatgatt
    27721 gatgaacatt atatagatag ttctgataac tttaaaacac taatagctct agtagataat
    27781 cataagtctg ttaaaaatgt agtagataaa ttaagaagag aaggaataga tgcatttcca
    27841 aaatcaactg taggtttatt agatgaatta tataaaacaa ttatttatat aggtactatt
    27901 atctctatta ctatatttat aatatctata attaatatat ctctaaataa tgtaaatgat
    27961 ttaaagaaga gacaaagtga attagggatg ttaaaatctt ttggatataa aaatagacaa
    28021 ttaaaaaaga taattattta tgaatctaca attataaata tgtttagttt atttatagga
    28081 ttagttattt gtaagcttat attcttgtta ttaaatacta tagtaaaaaa ttatctaagt
    28141 atatatatga gtgatcttaa atttgaaatt aatcttattt ctatttcaat tggaattttt
    28201 ataatgattt ttagtgttat attatcaaac ttaaaaagta tttcatatat aacaaattta
    28261 aatccaatac gtgctataag aagcaaatat tgattaaagg taataatata tgaaaaatat
    28321 aataaattta tcattattaa gtatcaaaag agataaatca aaaataaaga tatacattat
    28381 tatactaact atttttataa ctttaattaa tattttgctc aatacatcta taattttaac
    28441 tgatagtatt aacaacattt atataaatgt tgattatgaa atgataacta ctgtaaaata
    28501 tatcgttaat tcacttatta cattcataat tgtacttaca tttatactaa taaatatttt
    28561 attaaaacaa tctataaatg ataaattttt tgatatagca atttataaaa gtgttggata
    28621 taaagataaa tatatatttc aattactttt ttatgaatta ttcatagtaa ctacaattag
    28681 ttatttattt tcaattattc catcatttat aggtataaat gctattaatt taatattctc
    28741 gaaattcaat attcataata gt
//
LOCUS       DACTZW010000049        28293 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.049, whole genome shotgun sequence.
ACCESSION   DACTZW010000049 DACTZW010000000
VERSION     DACTZW010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28293
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.049"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            151..780
                     /locus_tag="JAM15_11435"
     CDS             151..780
                     /locus_tag="JAM15_11435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798864.1"
                     /translation="MNKYLLINPVAERMYGEKFHLIKANLIKKGYIIAECEPQLEYVK
                     KQYKEYTKKTENTMLDCRCPESISLLKRNNLINNFEVPMIEPILVRTCRVLYDKYIKS
                     KDDMLVVTCPCTQLRDFASEKFKDKGNAMFYTWKEFAEQEGVKSLGKIDESPIPLGYF
                     KDTFEKVLEVSSEDEILSEIQKIRNGFEDKYDIVEMFYCKDGCNNGDGL"
     gene            781..1563
                     /locus_tag="JAM15_11440"
     CDS             781..1563
                     /locus_tag="JAM15_11440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6798865.1"
                     /translation="MVNKFNNKFLRLVKSVLIFFIILLLWKITNYLGIWSDYILPSPE
                     KVYSTFLNMISDGSIFINVYASMKRVLIGFAISTAIGVPLGIFFGIYSGVYEYFKSLI
                     NFLRNTPPLALIPMLILWFGIGEESKIIIIVLASFFPIFTSTLKGIKNCDSKLIEVGR
                     VFEFSKLQIIFKIIIPNAILDIAVGLKLALGYSFRAIIGAELVAASSGLGYLISDGKE
                     MSRTDVVIVGIIVIGLLGIITDYIFSIIVKKVSKGKMVEAYE"
     gene            1556..2434
                     /locus_tag="JAM15_11445"
     CDS             1556..2434
                     /locus_tag="JAM15_11445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6798866.1"
                     /translation="MNNLVCDSGYIIRNLYKSYKVDNEEHVVLSDISLNIDRNHITVI
                     LGESGCGKTTLLRAIASLEGINSGEIRFINDNKEYRPNVGFVFQESRLMPWLNVSENI
                     AFHNQRKNTILNKVLRKFKHNKRIIGKIINDNFRSLETNDNLNKSNKYNRKSNIDVEK
                     YLKMMNLQKFKNSYPNELSGGMAQRVSIARALSFNPDMLLMDEPFSALDYFTRIDMQN
                     EVIKIHKSTNKGVIFVTHDIDEALKIGKKIVVFTDERKIKEFNIEDGYNRDLTSEYYI
                     KLKKDILMTMKSNKDI"
     gene            2467..3426
                     /locus_tag="JAM15_11450"
     CDS             2467..3426
                     /locus_tag="JAM15_11450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aliphatic sulfonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HAT6798867.1"
                     /translation="MKLKKLLIGITILTLATASLAGCAKKNNGEKLSEINLTYVKSPL
                     NVPSIIQKQDDLFGKEFKKDNIKVNFHEITTGPEQTQALAAGEIDFLHALGGTSALIA
                     ASNGVELKILNTYSRSPKGFMILTNNNSIKSAADLVGKKVAGPKGTILHQVLISALDK
                     EGLSMDDVEFVNMGIPEASAALSDGSVDVALIAGPAALKAMKSGSKLVANGEGLVDGI
                     IVTAVSTDFAEKHPEIVERFMKVEKETLEYVNNNFDEAMEKVAKEVDLSLEETKELYA
                     WYDFSLDITDKDISSLEDTQDFLIKNKLQEKKVNIKELIYNAK"
     gene            3740..4432
                     /locus_tag="JAM15_11455"
     CDS             3740..4432
                     /locus_tag="JAM15_11455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007060523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6798868.1"
                     /translation="MSYKVYIVEDDISISTLLKDYIEKYGFEVIVEENFDDIMITFES
                     FKPHLVLLDVNLPKFDGFYWCRCIRQQSNLPIIFISARDGNVDQIRALESGADDYITK
                     PFYYDVVMAKIKSHIRRVYGEYSPKIDERIVELDGLKFYPERLELELNGENLIITKKE
                     GILIECLIKRYPKVVSRDYLLEKIWDDIEFVEENSLNVNVSRIRKRFEELGIDNAVQT
                     VRGLGYKLNKNW"
     gene            4442..5446
                     /locus_tag="JAM15_11460"
     CDS             4442..5446
                     /locus_tag="JAM15_11460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAT6798869.1"
                     /translation="MKLFLKDYKGYIFIYYIGIVMTIIYCNLMKFISFGESLYILLFS
                     SFILLCFLIYKYYKNREVYNLFEKGIHSLEESFLYLGSSFLGRNISVILKQQHKLYQS
                     IIQEHKKIHSEHLTFINQWIHQMKTPISVISLQLQDYEGEEVTENIRKEIDRLNKGLD
                     MAMHFARADNFQKDFIVEKAKLNEIVSSIVNEEKRLFIKSGMIPKIQVDKFTYVYTDV
                     KWMKFIIGQLITNGVKYSKDYSNYLTIKSEENNKYVILSIIDEGIGIVSKDLKRVFDP
                     FFTGENGRKFGESTGMGLYLVKKVCDDLGHKVSIKSEVGKGTEVSIYFNKDVNSLIKV
                     "
     gene            5714..6565
                     /locus_tag="JAM15_11465"
     CDS             5714..6565
                     /locus_tag="JAM15_11465"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HAT6798870.1"
                     /translation="MSLDVIFILKSVIIAIVEGFTEFIPVSSTGHMILVGNLIDFKGQ
                     FAEMFEVVIQLGAILAVVVLYWKKIKDSVIEFFKFIFTGGKEGKIGFRFGMNVIIGCI
                     PFAIIGVLFYDNIKSLFNLQSVIIGFIVGGILLLVVETLFRKKNHSTDNIDKITPIQA
                     LKVGTLQVLSAWPGMSRSASTIMGGWIAGLNSPTAAEFSFFLAVPAMVASSGKDLFEF
                     DYSIMTPTLWIALVVGFIVAFIVSIIVMEKFVNFLKKKPMRVFAVYRIIMGVVLAVLA
                     FTNIISV"
     gene            6669..7415
                     /locus_tag="JAM15_11470"
     CDS             6669..7415
                     /locus_tag="JAM15_11470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007060520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6798871.1"
                     /translation="MKILTVNNLSKVYGKKIIFNALNDINFSIEDGEFVGIMGPSGSG
                     KTTLLNMISTIDKPTTGTMELKGKNPLLLRGEELALFRRRELGFVFQDFNLLDTLTIG
                     ENIVLPLTLDKVSVKEQDERLNEVSTILGIKDLLGKRTFEVSGGQAQRTAIARALINN
                     PSILLADEPTGNLDSKSSKVVMELFQKINKENKVTTMMVTHDPLAASYCSRILFIKDG
                     SIYNEIYKGSSREQFYQEIMDVLTLLGGDN"
     gene            7415..9331
                     /locus_tag="JAM15_11475"
     CDS             7415..9331
                     /locus_tag="JAM15_11475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6798872.1"
                     /translation="MNIKQFAINNISRNIKAYLGYLASIVISSSLLFSFIMFTSHPDL
                     DVSQFPDYLKEGLKMSKIIAYLFLFFFVFYSVSVFLKSRYKEFGILYITGISKRQVMK
                     LIFIENMIINIVSSVIGIIIGLIFAKIFLVVMYTFLELSPLKFYIPFNAILSTLIYFM
                     ILAVLTSIFTYFIVKENQVLKLLKGTKTPKPEPKTSLMLAILSICLFIIAYYNAITST
                     DQYTTYLRLVPVTSLTIVATYLFFSQFSVFFMKKLKLNKRFYRKNTNMLWISNLIYKV
                     KDNARIFFLITITSAVAFTAIGTVYSFWKDVERQINLIYPNTIYYSTMTLHNDPKKPD
                     SKEKDKERMMFIENNLKKENVDYTRTNGEFKTVFPKKSDFNVRIMKESKYLEITETIG
                     VKPISFEDNECISLLSSSLPGNNNVKENIIVGNRGLKVAKQVEECVMPAYYKNMYVVK
                     DNFYDSIESKFIVDRFTAFEVEDSSKTIEICREFENKFNNESGMQPYLFFSKELMIGT
                     GKLIYSTFIFLAIFIGLIFFVTTSSFLYNKFYMDCQVDKKKYEQLNKLGMTYNEIKKA
                     STIEIGIVFLFPYVVAVIHSIFALTALKNSFDIEVASSAVLVMGSLFLVQIVYFLIVR
                     NNYLKEIRLNLVNF"
     gene            9610..10527
                     /locus_tag="JAM15_11480"
     CDS             9610..10527
                     /locus_tag="JAM15_11480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HAT6798873.1"
                     /translation="MMILIQSRGKMKCKELSEELEVSERQIKSYKMYLEQAGIFINST
                     PGIYGGYEIDKCNSISLIKLLDSEVSILDMINSQLEYNNDIYKNEFNNIVEKIKAVLN
                     TGEKSDTYMDYFTVQAQRNCDYESEKNKCNEIIRAYTTKHKFWIEYYSLNSGNSERIV
                     HPYGLFNYKSDTYMVAFCEKRFKFIDFKLCRIKDYKVLEEKYNVDKSFSWDEYSKNSI
                     GIYKGEEINVVIKISHPFSIIIKEKVWVNNQQIIEYDDKSIMFKAKMRGYEEIKSWIL
                     SMGAYVEVVEPDRLRNDILSEIEKMKKIY"
     gene            10605..11342
                     /gene="cas6"
                     /locus_tag="JAM15_11485"
     CDS             10605..11342
                     /gene="cas6"
                     /locus_tag="JAM15_11485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HAT6798874.1"
                     /translation="MKMKIEFSTGCIPISYNSLFMSIIKEAIRKSNEDYYKNMYYYKE
                     KNNKKTKNFTFSVYIKKYSIEGDNFIIEDKVILNISTPDLELGFHIYNGLMTSKKCLY
                     KAYELTRIRIDLSREKKVTEERVLFNALSPICVKSKEGKFLEITDDRYIEELNYITNE
                     VVKNYRGNGLKRKLEFENIGLKKIVVKESLREFKKITGKEYQYINGYKGKFILKGDID
                     DLNLIYNLGIGFRRAQGFGDVDILEWR"
     gene            11348..13225
                     /gene="cas8a1"
                     /locus_tag="JAM15_11490"
     CDS             11348..13225
                     /gene="cas8a1"
                     /locus_tag="JAM15_11490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas8b1/Cst1"
                     /protein_id="HAT6798875.1"
                     /translation="MKLRVYRGDWFFNMGIVGFLNIIKKADKQAEIFIMEDYIEFDSL
                     FLENFHEYYFNYFMDEYDVSKRIKKNIDYSINFIKSKPDRIKDGIKKIKDSVKQQNDK
                     IKKFDEEKFNLIKEKLDSMSKIKSYDEFDSLEALVDETIDIFKIKSINDRLTANLYKY
                     VVQDNYFGQVSFFNVAKAKLDLDGLKQVMFNDYLRQIIYFGELADLLEENDYDKLKNY
                     LNDRLNSIAKDINEKKVSKSSINTIEKIMKEINKNFIKKNKSIEDIKEYMDSLEVCEM
                     CGLYKGILDEYSESNFAPLGVSTNNARNMFWNQAYVPSICDICKLILFCTPAGATYTR
                     KNYLINEENEFYLFVNMDTSINELFERNNSLKAQKSEYSDSKDENPFNQLIKSIVEEN
                     TLKSEWQLRNILFVEFKASIDSKKCKINYFNIPTYLAKFFTDKYANKKIQSIYDYKLK
                     SNILDLLLKNRDLKHLTNNILRNKVKNDMESNNKSNISGIDCFRVVQLRALINSYKKG
                     VYKMDSKNLEKNDEKLRIIYYLGCDIHDYFVNKNSKNKIDGVSYKLLNSVKVGNKSDF
                     MDTIIRVFMSAEKQIPAFILDIEIEKDLDFESIGHAFISGLISGKYEGKDKLPNEKEE
                     K"
     gene            13227..14141
                     /gene="cas7i"
                     /locus_tag="JAM15_11495"
     CDS             13227..14141
                     /gene="cas7i"
                     /locus_tag="JAM15_11495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein
                     Cas7/Cst2/DevR"
                     /protein_id="HAT6798876.1"
                     /translation="MKRGLTFTVIAQAQSLNYGEGIGNISELKKLSRDDGNIYTFASR
                     QCLRYDIVRLAAELFNWNLQVVDKEKGTIQFKDNISIRESEEMDLFGYMKTNKKDEKD
                     KKGGSLTREATVRLSNAISLEPYRSDMDFLNNKGLADRIGEHPNLANIEQHLSYYTYT
                     VTIDLSKIGKDGDIELDNKEKCRRVVEFLEIIKVLNRNIRGRQENLSPLFVVGGVYEI
                     ANPFFLGRIKLKGDKNGFKINKQAIEEVIQGTFLGKDLKEFTYVGMVDGVFINKEEFK
                     GLFEDNFLSVDKFFGQLVKEVKEYYGVN"
     gene            14143..14844
                     /gene="cas5b"
                     /locus_tag="JAM15_11500"
     CDS             14143..14844
                     /gene="cas5b"
                     /locus_tag="JAM15_11500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas5"
                     /protein_id="HAT6798877.1"
                     /translation="MKVLKLDLFQETACYKKPFAMKITETYPLPPYSTINGLIHKILN
                     ATEYIPFNISVQGTYESIFNNYQTTYFYKKDSITSMPMNSHMLLNVNLIIHIGGDFDL
                     LEEIYDSLLNYDEHLSLGRKEDLVRINDIRFVEVNKFEVDEDIQLDDYENYKLSECNI
                     RMPIYIPKTSLQDTDIDGISYRLNNYYDNNAVEDKKRVWNKVDSYYVEDGNTISIGDI
                     LLDNEGDLLYFNNIN"
     gene            14855..17176
                     /locus_tag="JAM15_11505"
     CDS             14855..17176
                     /locus_tag="JAM15_11505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HAT6798878.1"
                     /translation="MLYAKSNPVETLREHTDELLKQMNVLRESYGKNINSLDFLEEEI
                     FWQLLDFVIEFHDIGKAFSPFQELIKSRMDTKINEPKIVTHLENNVGHNYLSPAFIDY
                     SYIDRKKNKELRAVLNQVIVYHHERDIFIDKDFKNLIQKILDEDLINKVYELQRKFKV
                     RYPIKTEKLSKVYLQSVEKRIDKNHKYYNLYIMLKGILHRLDHSASAHEVVECNNVIN
                     IGEQTENYLMKEFGSLREAQSFAKSNRNKNIILIASTGMGKTETALIWIDKDKAFFTL
                     PLRVSINALFDRAKNIVGVGESNDTFLGLLHSTAIDYLEESNQENSSEIVDLAKLLSC
                     KLTFSTIDQIFKFPFLYRGYEKVYSTLAYSKVVIDEIQAYSPEIAAVLVKGIEMIHKI
                     GGRFMIMTATMPTIYIDELKKRGVMNSNLAELTCNTEKIRHCVSIVENSIDENLGKII
                     QSGMNKKVLVIVNTVKSAVEKYELIEEIVKPKGIDVNLNLLHSMYIQEDRAKLEKYIK
                     EFANSDRNGIWITTQLVEASLDIDFDELHTENSTLDSLFQRFGRCYRSREYEENSPNI
                     FIYTEKATGIGSIYDKDIVEKGLELLKTFINGKECVKMKEKYKVEMVKILYSKESLEG
                     TAFEKRFTSALNILDTITPYSLGSKDAQNILRNIEGYTVIPEDIYNKIEETLIKDYEE
                     LGQELINAYSNDDRQLINKIKSKRKKARREIIKKTVNLPIYKAKQNVIDIQVKGLEDL
                     KILLYKYDIHENKHTKQIFGKGVLISNEIDQFI"
     gene            17224..17742
                     /gene="cas4"
                     /locus_tag="JAM15_11510"
     CDS             17224..17742
                     /gene="cas4"
                     /locus_tag="JAM15_11510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015394873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas4"
                     /protein_id="HAT6798879.1"
                     /translation="MPIDLEVLKVQGVKINYYYVCKRKLWLFSKGITMEQNSSRVLSG
                     KIVHEDSYKRMKNKEMLIDDILKLDIIKDEYVKEVKISSKMKEADEMQLYYYLYYLKN
                     SMGIEKKGTINYVKEKKQEELILTEEKEKIIENTLININEINMQLSPPKIEKKHYCTK
                     CAYYEFCFVKEE"
     gene            17745..18725
                     /gene="cas1b"
                     /locus_tag="JAM15_11515"
     CDS             17745..18725
                     /gene="cas1b"
                     /locus_tag="JAM15_11515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015394872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated endonuclease Cas1"
                     /protein_id="HAT6798880.1"
                     /translation="MYKDYYIISNGNIKRKENTIYYYNLEGEKKILPVEQVDDIHIYG
                     EVDLNTKLINYISKYGVMLHFYNYYGYYSGTYYPRKKNVSGFSLVCQSACYLDKNERL
                     YLAKSFVESASYHILRNMRYYKVDESLIDTIKDELNDLNDVKEISELMGKEGRIRKTY
                     YKSFNQILKDDFEFYKREKRPPKDSVNALMSLGNSIMYTNVLSEIYKTQLDPTISFLH
                     EPSTKRFSLSLDIAEIFKPIIVDTIIFSLINNKRINKNDFEYQDKICYLSEKGKKKFL
                     QEFENKMQTTIKHRNLNRKVSYRMFIRLECYKLIKHFINDERYKVLKAWW"
     gene            18728..18994
                     /gene="cas2"
                     /locus_tag="JAM15_11520"
     CDS             18728..18994
                     /gene="cas2"
                     /locus_tag="JAM15_11520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HAT6798881.1"
                     /translation="MFVIVTYDIVEARSLNRIRRILRKYLTWTQNSVFEGNITDGKLH
                     KCISEIENIIDNSEDSIYVYEIKNPNSIKKKCYGIDKYSDEMFI"
     repeat_region   19178..21181
                     /inference="COORDINATES: alignment:crt:1.2"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=19178..19206
                     /rpt_unit_seq="gttttatattaactaagtggtatgtaaat"
     gene            21242..21670
                     /locus_tag="JAM15_11525"
     CDS             21242..21670
                     /locus_tag="JAM15_11525"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAT6798882.1"
                     /translation="MIKKLNNKDINKIMEIWEKSTIKAHDFISKEYWQNNYNTVKNEY
                     IPISDTFVYDDGDEIKGFISIIDKSFIGALFIKPKYQNLGIGGKLLDYATKKYKSLSL
                     AVYKDNKKAVVFYNKKGFNIVKEQVNEDSGFKEYIMEYSK"
     gene            complement(22126..22896)
                     /locus_tag="JAM15_11530"
     CDS             complement(22126..22896)
                     /locus_tag="JAM15_11530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798883.1"
                     /translation="MKVNENNIDEELDELSRKVYLESPDFWISISDKIIDKVFDEMLL
                     FFAVKYNYFNIVCFAIENNYLDLNMPSKNKKYTNIMEHLLDTSKQNEDKKIYNYLLSL
                     NKGNNLDERPILDELNCNISSDTFEKKDIYLPKYLCPSCNSNIFDTGYKVSNDITYKF
                     SSKEAEPIEMSSEVSSIRCCNCDELLEDITLNKLYNLCKIQNCNNCGSNLTKVGIIAK
                     KKMNFDENTEKFKDVSTSYCCGNCDSEINLSQREHFKI"
     gene            23220..23765
                     /locus_tag="JAM15_11535"
     CDS             23220..23765
                     /locus_tag="JAM15_11535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HAT6798884.1"
                     /translation="MKNTKVNIQDLTKMSICVALLCISSYIYIPLPFTPAGVTAQTIM
                     INLIALILTPRQAFSTVGVYIMIGLIGIPVFGGGTSGIGKLLSPTGGFYFGFLFAALI
                     ISLLKGRNNDIKRYILITTFVGMPIIYFMGTVFMCYFNQMTVEAALFAAVVPFLIGDT
                     IKSVIASFLGTKLNNVLRRNL"
     gene            23797..24933
                     /locus_tag="JAM15_11540"
     CDS             23797..24933
                     /locus_tag="JAM15_11540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiolase family protein"
                     /protein_id="HAT6798885.1"
                     /translation="MKEVFILGGLRSHIGLKNGIFQFVQPELLGASVLKDLIKKYEID
                     KIDEIICGNAVGTGGNIARLMTLTAGVSNEVPAFTVDMQCASAMMSIDIAFSKVKSGQ
                     CNLIIAGGFESSSLQPMRTYHKNDKRYDTNNPNYTVAQFSPDDNSQNSMLEGAERVAA
                     LYQIERADLDFWVKESHKRAKEAREEKILEDIISPINNSTYDEGIRDKMSQRLLDRMP
                     PILGKETITNAANSCLINDGASFIIICSKKYLEHVKKKPKAKIINTCTIGTDATLSPT
                     SAIQAMDKLLEIESLNYLDVSAVEFNEAFAVIDVLFQRKYPELIERYNIFGGALAYGH
                     PYGASGAIIALHLLKALEKTKGRYGICSIAAAGGLGSALLLERV"
     gene            24937..26328
                     /locus_tag="JAM15_11545"
     CDS             24937..26328
                     /locus_tag="JAM15_11545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long-chain fatty acid--CoA ligase"
                     /protein_id="HAT6798886.1"
                     /translation="MNYYELLRIKKERHKNKNFLIIDGEKYTYENILSYSEELGKQIS
                     LGENIPILIYSKNIMFQLISFFAINYSKNIPIICHYNLSKKVLDDILLKNNISIIISD
                     ESMDVIDLYDDNNNEVAKKVNFSIFNPKFNIYMYQYKNLINYLDKSICMGALSSGSTS
                     VPKVLYRTYESWAGFFPIQNGIFNISGESILFVNGTLSFTGNLNSIMSVLYEGGSIVI
                     SSGLNCKSWIRTIKQYNVTNIYLIPTKLQLLVKHLKEPVLKVVSIFTGSQLLFEYTAR
                     NLKKYMPKSEIILYYGASELNYITYLCYDELIEKPLSVGRPFPGIDIYIRGGKIFVNT
                     EYAVYNATKPYSVNDIGYYDNDGYLIFEGRSDDIVNIGGFKVSSAKIENEVKKIPQIE
                     DAIVLPYSDTIRGNQIVLFVITIDKITKKDLLIKMKDNLMKNEIPKKIIFLNSFPYTS
                     SEKIDRLALLKML"
     gene            26404..27279
                     /gene="dpsA"
                     /locus_tag="JAM15_11550"
     CDS             26404..27279
                     /gene="dpsA"
                     /locus_tag="JAM15_11550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit DpsA"
                     /protein_id="HAT6798887.1"
                     /translation="MSNQYDITVIGGDLRQVYMVKKLINKGYSVVTYGISNEIINGIV
                     GKSTSLAEALSKSSIILCPIPFTKNQVNIENTDDCLDATIDNLLINLSPNQILFGGNI
                     PTKVCKFCEQHSIQIYDFMKMNDVAILNAVATAEGAIAEAIKRSIINIHQSNCLVLGY
                     GRCAQILAKKLYALDANVCVGARNNDARSTANAFGYSSISLSQLDEKLLQFDYIFNTI
                     PECILTKERLEKVSQEVTIIDIASSPGGVDYSVVKEVGINATLCLGLPGKYSPKTSGE
                     ILVNAIENIINERRD"
     gene            27282..27872
                     /locus_tag="JAM15_11555"
     CDS             27282..27872
                     /locus_tag="JAM15_11555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit B"
                     /protein_id="HAT6798888.1"
                     /translation="MRLEGLTIGVGFTGSFCTYDKIFIELENLVKEGANVHTIFSDVS
                     QNIDCRFGNSEEFMKKAYELTGNKPIVTIEEAEPFGPKGIADIIIIAPCTGNTAAKLA
                     NGITDSPVLMAAKGHLRNDKPLVISISTNDALSFNFKNIGILLNSKNIYFVPFGQDNC
                     KAKPNSMIAHTELIIPTIELALENKQLQPVIKSPHQ"
     gene            complement(28080..28280)
                     /locus_tag="JAM15_11560"
     CDS             complement(28080..28280)
                     /locus_tag="JAM15_11560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798889.1"
                     /translation="MKKLKTISIFSLIISVILTIGGIGIVTYYVDNLFIRGLSVFVLI
                     MSSSFVSTTVRLIFEESKRYKF"
BASE COUNT        11342 a         2729 c         4716 g         9506 t
ORIGIN      
        1 acatatacta tttaatattt catttaaaat attaaaaaat gtagataaaa attgttttat
       61 taagaaaaaa ttaatatatt gacaaaattt aagtgctcat ttaaactatt aattgataat
      121 aatattcaat attaaataat aggaggcgtt atgaataaat atcttctaat aaatccagtg
      181 gcagaaagaa tgtatggaga aaagtttcac cttattaaag caaatttgat aaaaaagggg
      241 tacataatag cagaatgtga accacagtta gaatatgtaa aaaagcagta caaagagtat
      301 acaaaaaaga ctgaaaatac aatgttggat tgtagatgtc cagaaagtat aagtctttta
      361 aaaagaaata atttgataaa taattttgaa gtacctatga tagaaccaat attagtaagg
      421 acttgtaggg ttttatacga taaatatata aaaagtaaag atgatatgtt ggtagtaacc
      481 tgtccatgta cacaattaag agactttgca agtgaaaagt ttaaggataa gggtaatgct
      541 atgttttata catggaaaga gtttgctgaa caagaaggtg taaaatcact tggaaaaata
      601 gatgaatcac caattccatt aggatatttc aaagatactt ttgaaaaagt tcttgaagta
      661 tcaagtgaag acgaaatatt aagtgaaata caaaaaataa gaaatggctt tgaagataag
      721 tatgacatag tagaaatgtt ttattgtaaa gatggttgta ataatggaga tggtttgtaa
      781 atggtcaata aatttaataa taagttttta aggctagtaa agagtgttct gatatttttt
      841 ataattcttt tattatggaa aattacaaat tatcttggta tttggagtga ttatatatta
      901 ccatcacccg aaaaggtata tagtacattt ttaaatatga taagtgatgg ttcaatattt
      961 attaatgtat atgcaagtat gaaaagagtt ttgataggtt ttgcaataag tactgctata
     1021 ggtgtgcctt tagggatatt ctttggaatt tatagtggag tatacgaata ctttaaatct
     1081 ctaataaatt ttttaaggaa tacacctccc cttgctttaa taccaatgct tatattatgg
     1141 tttggtatag gagaggaatc aaaaattata attatagttt tagcatcctt tttcccaatc
     1201 tttacaagca cattgaaagg gattaaaaat tgtgactcaa aactgattga agtgggtaga
     1261 gtatttgagt tttcaaagct tcagataata tttaaaataa taataccaaa tgccattctt
     1321 gatattgctg ttgggttaaa gttagctctt ggatatagct ttagagcaat tattggggca
     1381 gaacttgtag cagcttcatc tggtcttgga tacttgatat ctgatggaaa agaaatgtct
     1441 agaacagatg ttgttattgt aggtataatc gtaattggac ttttaggaat aattacagat
     1501 tacatatttt cgattattgt gaagaaggta agtaagggaa agatggtgga agcatatgaa
     1561 taatttagta tgtgactctg gatatataat tagaaattta tataaaagtt ataaagttga
     1621 caatgaagaa catgtagttc ttagtgatat ctctttaaac atagatagaa accatataac
     1681 agtaatttta ggtgaaagtg gttgtggaaa gactaccttg cttagagcaa ttgcatcact
     1741 tgaaggtata aatagtggtg agattaggtt tattaatgat aataaagagt atagacctaa
     1801 tgttggtttt gtttttcagg agagcagatt aatgccttgg ttaaacgtaa gtgaaaatat
     1861 agcttttcat aatcaaagaa aaaatactat tttaaacaag gtgcttagaa aatttaaaca
     1921 caataaaaga attattggta aaattataaa tgataatttt agaagcttag aaacaaatga
     1981 taatttgaac aaatcaaata aatataatag gaaaagtaat attgatgtag aaaaatatct
     2041 taagatgatg aacttgcaga aatttaaaaa ctcttatcca aatgaattgt caggaggtat
     2101 ggcacagaga gtaagcatag ctagagctct ttctttcaat ccagatatgt tgcttatgga
     2161 cgagcctttt tcggcattag attattttac aaggattgat atgcaaaatg aagttataaa
     2221 aatacataag tcaactaata aaggcgtaat atttgtaact catgatattg atgaagcgtt
     2281 aaagataggc aaaaaaatag ttgttttcac agacgaaaga aaaataaaag aatttaatat
     2341 agaagatggt tataatagag atttaacttc agagtactat attaaattaa aaaaagatat
     2401 tttaatgaca atgaaatcaa ataaagacat ttaaagaaat taataatatt ttaaggagta
     2461 gagtaaatga aattaaaaaa gctattgata ggtataacga tattaacact tgcaacagca
     2521 tctttagctg gatgtgctaa aaaaaataat ggagaaaaac tttcagaaat aaatttaact
     2581 tatgtaaaat caccattaaa tgttccttct ataattcaga aacaggatga tttatttgga
     2641 aaggaattta aaaaggataa tataaaagtt aactttcacg aaattactac aggtccagag
     2701 caaacacagg ctttagctgc tggagaaata gacttcttac atgcactagg tggtacgtca
     2761 gctttaatag ctgcatctaa tggagtagag ttaaagatat taaacactta tagcaggtca
     2821 ccaaaaggat ttatgatttt gactaataat aattcaataa aatcagcagc agatttagta
     2881 ggtaagaagg tggcaggtcc aaaagggact atattacatc aggtattgat ttcagcactt
     2941 gataaagaag gattaagtat ggatgatgtg gaatttgtta atatgggtat tccagaagca
     3001 tcagcagctc tttctgatgg tagcgtagat gttgcattga ttgctggtcc agcagctctt
     3061 aaagctatga agtcaggtag taaacttgta gcaaatggtg aaggtttagt agatggtata
     3121 atagtaactg ctgttagcac agactttgca gagaaacacc cagaaatagt tgaaagattt
     3181 atgaaggttg aaaaggaaac tttagaatat gtaaataata attttgatga agctatggaa
     3241 aaagtagcta aagaagttga tttaagtctt gaagaaacta aagaattata tgcttggtat
     3301 gattttagtt tagatataac agataaagat atatcttcgc ttgaagatac acaagacttc
     3361 ttaataaaaa ataagttaca agagaaaaaa gtgaatataa aagaattaat ctataatgct
     3421 aagtagaaac tatgctaaaa taatactaag taagaaatat aataaaagtt taagttacct
     3481 tattaaggta actttttcta ttttgaatta gtaatttcaa tttattttag aatgattagt
     3541 tgataataat gattaattaa tcataaaaag atactttttt atagagtttt attaagatgt
     3601 ctaataatat ggttatactt atgaagtcag taattgtgaa gttaataata tgattaaatt
     3661 tatatattgt aaaaagatta taatatatta aaattggact gttatatgat gagtaaatag
     3721 gtatattagg aggaattata tgagttataa agtatatatt gtggaagatg atatatcaat
     3781 aagtacatta cttaaagatt atattgagaa atatggattt gaagtgattg ttgaagagaa
     3841 ctttgatgat ataatgatta catttgaaag ttttaagcca cacttagttc tattagatgt
     3901 aaatttacct aaatttgatg gtttctactg gtgtagatgt attagacaac agtcgaattt
     3961 acctataatt tttatatcag ctagagatgg caatgtagac caaattagag ctttagaaag
     4021 tggagcagat gattatataa caaaaccttt ttactatgat gtagtaatgg caaaaataaa
     4081 gagtcatata agaagggtat atggtgaata ttcacctaaa atagacgaaa gaatagtgga
     4141 gctagatgga ttaaagtttt atccagaaag gttagaacta gaattaaatg gtgaaaatct
     4201 aattataact aaaaaagaag gtatactgat tgaatgtctt atcaagagat acccaaaagt
     4261 agtaagtaga gattatcttt tagaaaagat atgggatgat attgagtttg tagaagaaaa
     4321 ttctttaaat gtaaatgtta gcaggataag gaaaagattt gaggaattag gtatagataa
     4381 tgctgttcag actgtccgag ggttaggata taaattaaat aagaattggt aaggagaaag
     4441 tatgaagtta tttttaaaag attataaagg ttatattttt atatattata taggcatagt
     4501 tatgacaatt atttactgta atcttatgaa gtttattagt tttggagaga gtttatatat
     4561 tcttttattt agttctttta tattgttatg ttttttaata tataagtatt ataaaaatag
     4621 agaagtatat aatctgtttg aaaaaggaat acattctttg gaggagtcat ttttgtattt
     4681 aggaagctca ttcttgggga gaaatatatc agttatttta aaacaacaac ataaattgta
     4741 tcaatcaata atacaagagc ataaaaagat acatagtgaa catttaactt tcatcaacca
     4801 atggattcat cagatgaaaa caccaatatc agttataagc cttcagcttc aagattatga
     4861 gggagaagaa gtaactgaaa atataagaaa agaaatagat agattaaata aagggttaga
     4921 tatggctatg cattttgcaa gggcagataa ttttcagaaa gactttatag ttgaaaaagc
     4981 caaattaaat gaaattgtat ctagtattgt aaatgaagaa aaaaggttat ttataaaaag
     5041 tggaatgatt cctaagattc aagtagacaa atttacttat gtttatacag atgtaaaatg
     5101 gatgaaattt ataataggtc aattaattac aaatggagtg aaatattcta aagattatag
     5161 taactaccta actataaaat ctgaagaaaa taataaatat gtaattttaa gtataataga
     5221 tgaaggaatt ggaattgttt ctaaagattt aaaaagggta tttgacccat tttttacagg
     5281 agaaaatggt cgtaagtttg gagaatctac aggtatgggt ctttatctag taaaaaaggt
     5341 atgtgatgat ttaggtcata aagtaagtat aaaatcagaa gtaggaaaag gtacagaagt
     5401 ttcaatctac tttaataaag atgtaaatag tttaataaag gtataaatag tttgataaag
     5461 atgtaaatta tctgttacaa tagggttttt agttaattgt acttttttat tatacaattt
     5521 attaaatgaa atattcatag ttaaataatc aaaatttaag agagtttatt tgcaaacctt
     5581 acatagatgt aaggtttgtg taatgtttgc agatagttaa attttctaat ctaaattaca
     5641 attaatataa gaaataacat aagagaaata acataaaaaa agaaattttg taaaaaagga
     5701 aggatgttta ttgatgagtt tagatgttat ttttatattg aaatcagtca taatagctat
     5761 agtagagggg tttacagaat ttattccagt ttcatctaca ggtcatatga ttttggttgg
     5821 taatttaata gattttaagg ggcaatttgc tgaaatgttt gaggttgtaa tacaacttgg
     5881 ggctatatta gcagtagtag tactttattg gaaaaagata aaagatagcg ttatagaatt
     5941 ttttaaattt atatttactg gcggaaaaga aggaaagatt ggttttagat ttggaatgaa
     6001 tgtaattata ggttgtatac catttgcgat tataggagtt ctattttacg ataatataaa
     6061 atcattgttt aatttacaat ctgtaattat aggatttata gtgggcggga ttttattatt
     6121 agtagtagaa actttgttta gaaaaaagaa tcattccaca gataatatag ataaaattac
     6181 tccaatacaa gctttaaagg ttgggacatt acaagtttta tctgcatggc caggtatgtc
     6241 aaggagtgca tctactatta tgggtggatg gatagcagga cttaattctc ctacagcagc
     6301 tgagttttct ttctttttag cagtaccagc tatggtggct tcttcaggaa aagatttatt
     6361 tgaatttgat tattcaataa tgacaccaac attgtggatt gctttggtag ttgggtttat
     6421 agtagctttt attgtatcaa taatagttat ggaaaaattc gtgaattttt taaagaaaaa
     6481 accaatgaga gtgtttgctg tatacagaat aatcatgggt gtagtacttg cagtattagc
     6541 ttttactaac ataattagtg tatagaaaaa atagatttat tatctataaa aattaaacta
     6601 agataaatta taattaacaa ttatatatat gttatttcaa aaattaaatt aggaaggata
     6661 gttaaataat gaaaatttta actgtaaata atttaagtaa agtatatggt aaaaaaataa
     6721 ttttcaacgc attaaatgac ataaatttta gtatagaaga tggagaattt gtaggaatta
     6781 tgggtccatc tggtagtgga aaaactactc ttttaaatat gatttctact attgacaagc
     6841 caactacagg aactatggaa ttaaagggaa agaatccttt attgttaaga ggtgaggaac
     6901 ttgcattatt tagaagaaga gagttaggtt ttgtatttca ggattttaat ttattggata
     6961 cattaactat aggagaaaat atagtattgc cattgacatt agataaggtc agtgtaaaag
     7021 agcaagatga gagattgaat gaagtatcta caatattagg tataaaagat ttattaggaa
     7081 aaagaacttt tgaagtatca ggtggtcaag ctcagaggac tgctattgct agagcattga
     7141 ttaacaatcc atcaatactt ttagcagatg aaccaacagg taatttagat tcaaagtcat
     7201 caaaggttgt aatggagcta tttcaaaaga taaataaaga aaataaagtt actactatga
     7261 tggtaactca tgacccatta gcagcgagct actgtagtag aatcttattc ataaaagatg
     7321 ggtctatata taatgaaata tataagggta gtagtagaga gcagttttat caagagataa
     7381 tggatgtact tacattattg ggaggcgata actaatgaat ataaaacagt ttgctattaa
     7441 caatatttca agaaatatta aagcgtattt aggatactta gcaagtattg ttatatcatc
     7501 ttcactgcta ttttctttta ttatgtttac aagtcatcca gatttagatg tatctcaatt
     7561 tcctgattat ttaaaagaag gtctcaagat gagtaagata attgcatatc tattcttatt
     7621 cttctttgtg ttttattcag ttagtgtgtt tcttaaaagt agatataaag aatttggaat
     7681 actttatatt acaggtatat caaaacgcca agtaatgaaa ttaatcttta tagaaaatat
     7741 gataataaat atagtatctt ctgtaattgg aataataata ggcttaatct ttgcaaagat
     7801 atttttagtg gttatgtata cttttttaga attatcgcca ttaaaattct atataccatt
     7861 taatgcgata ttgtctactt taatctattt tatgatttta gctgtattaa catcaatatt
     7921 tacttatttt atagttaaag aaaatcaggt gttgaagtta cttaaaggta caaaaactcc
     7981 aaaaccagag cctaaaacat cactaatgct tgctatatta agtatttgtt tgtttataat
     8041 agcgtattat aatgctatta cctcaaccga ccaatataca acatatctgc gcttagttcc
     8101 agttacatcc cttactatag tagcaactta cttgttcttt tctcaattta gtgtattttt
     8161 tatgaagaag ctaaaactaa acaagagatt ttatagaaaa aatacaaata tgctttggat
     8221 ttcgaacttg atttataagg taaaggataa tgctagaata tttttcttga taactataac
     8281 ttctgcagta gcatttactg ctataggtac agtttattcc ttttggaaag atgtagagcg
     8341 tcaaattaat ttaatatatc ctaacacaat atattattca acaatgacat tgcataatga
     8401 ccctaaaaag cctgatagca aagaaaaaga caaggaaaga atgatgttta tagaaaataa
     8461 tctaaaaaaa gagaatgtag actatacaag gactaatggt gaatttaaaa ctgtatttcc
     8521 caagaaaagt gattttaatg tcagaattat gaaagaatct aagtacttag aaattacaga
     8581 aactataggg gttaagccta taagttttga agataatgaa tgcatatcat tattatcatc
     8641 aagtttacca ggaaataata acgtcaaaga aaatattatt gtagggaata gaggtttaaa
     8701 ggtggcaaaa caagtggaag aatgtgttat gccagcatat tacaaaaata tgtatgtggt
     8761 aaaggataat ttttatgata gtatagaatc aaaatttata gtggatagat ttactgcatt
     8821 tgaagtagag gattcaagta aaactataga gatatgcaga gaatttgaaa ataaatttaa
     8881 taatgagtca gggatgcaac catatttgtt tttctctaaa gaattaatga taggaactgg
     8941 gaaattaata tattctacat ttatattttt agcaatattt ataggtttaa ttttctttgt
     9001 tactacaagt agttttttat ataataaatt ttatatggat tgccaagttg ataagaaaaa
     9061 gtatgagcaa ttaaataaat tggggatgac atataatgag attaaaaaag cttcaacaat
     9121 tgagattgga atagtatttt tgtttcctta tgtagtggct gttatacatt caatatttgc
     9181 acttactgca ctgaaaaatt cttttgatat agaagtagca tcatcagctg ttttggtaat
     9241 gggaagcttg ttcttggttc aaatagttta ttttttaatt gtaagaaata attatttaaa
     9301 agagataagg ttaaatttag tcaattttta gttactatta ttaaatgata ataaaaaggg
     9361 tttaaaatta attaatatta ctggaattat agatgtttat tttttcagta atatttttta
     9421 ttgtattaac tattaaaatt ttgtacaaat ataaaatata atatggtaaa tgtcaaaatt
     9481 ataaaaaaat tctacttata taaaatataa agaggttata tgtacatatg tgtagaaata
     9541 aataataaaa atatcaatta atgttattag ggggggttac tcattagtaa attagctaat
     9601 acacttagaa tgatgatatt aattcaaagc agaggcaaaa tgaaatgcaa agaattatca
     9661 gaagagttgg aagtaagtga aaggcaaata aaaagttaca agatgtattt agagcaagct
     9721 ggtatattta taaattcaac acctgggatt tatggtggtt atgaaataga taaatgtaat
     9781 agcatttcat taattaaatt attagatagt gaagtttcaa ttctagatat gataaattca
     9841 cagttagagt ataataatga tatttacaaa aatgaattta ataatattgt agaaaaaata
     9901 aaagcagtat taaatacagg agaaaaaagc gatacatata tggattattt tacagttcaa
     9961 gcacaacgta attgtgatta tgagtctgaa aaaaataagt gtaatgaaat aattagagca
    10021 tataccacaa aacacaaatt ttggatagaa tattattcat taaattcagg aaatagtgaa
    10081 agaattgttc atccatatgg tttatttaat tataaatcag atacttatat ggtagctttt
    10141 tgtgaaaaaa gatttaagtt tatagacttt aaattatgta gaattaaaga ttataaggtt
    10201 ttagaagaaa aatataatgt agataaaagt tttagttggg atgaatatag taaaaatagt
    10261 ataggaattt ataaaggaga agaaattaat gttgttataa aaattagtca tccattttca
    10321 ataattataa aggaaaaagt ttgggttaat aatcaacaaa tcatagaata tgatgataaa
    10381 tctataatgt ttaaagctaa aatgagaggt tatgaggaga taaaaagttg gattttaagt
    10441 atgggagctt atgttgaggt tgtagaacca gatagactta gaaatgatat attgtcagag
    10501 attgaaaaaa tgaaaaaaat ttactgattt tttcaaataa tttatacttg gaccaatata
    10561 cttcacggtc tagtgttaat atattaattg agagaggtga tattatgaaa atgaaaattg
    10621 aatttagtac aggttgtata ccaatatctt ataattcgct ctttatgagt attataaaag
    10681 aagcaataag aaaatctaat gaagattact ataaaaacat gtactattat aaagaaaaga
    10741 ataataaaaa aactaaaaat tttacatttt cggtttatat aaaaaagtat agtattgaag
    10801 gtgacaattt tattatagaa gataaagtaa tattaaatat aagtactcca gatttagaat
    10861 tgggttttca tatatacaat gggttaatga cttctaaaaa atgtttatat aaagcctatg
    10921 aacttacaag aattagaatc gatttatcaa gagaaaagaa ggtaacagaa gaaagggtac
    10981 tatttaatgc attgtctcca atctgtgtaa agtctaaaga aggaaaattc ttggagataa
    11041 ctgatgatag atacatagaa gaactaaact atataactaa tgaagtggtt aaaaattata
    11101 ggggaaatgg attaaaaaga aagttagaat ttgaaaatat aggtctcaaa aagatagtag
    11161 ttaaagagag cttaagagaa tttaaaaaaa taacaggtaa agagtatcaa tatattaatg
    11221 gttacaaagg taaatttata ttgaaaggtg atattgatga tttaaatctt atctacaatc
    11281 taggaattgg ttttagacgt gctcagggat ttggagatgt agatatttta gaatggaggt
    11341 gagataaatg aagttaagag tttatagagg agattggttt tttaatatgg gtatagttgg
    11401 atttttaaat ataataaaga aagcagataa acaagctgaa atatttatta tggaagatta
    11461 tatcgaattt gatagcttat ttcttgaaaa ctttcatgag tattatttta attactttat
    11521 ggatgaatat gatgtatcaa aaagaattaa aaaaaatatt gattacagta taaattttat
    11581 taaatctaag cctgatagaa tcaaagatgg aattaagaaa attaaagata gtgtgaaaca
    11641 acaaaatgat aagattaaaa aatttgatga agaaaaattt aacctgataa aagagaagct
    11701 agatagcatg tctaagataa aaagttatga tgaatttgac agtttagaag ctttagtaga
    11761 tgagactata gatatattta aaataaaatc aataaatgac aggcttacag caaatcttta
    11821 taaatatgta gttcaagata attattttgg acaagttagt ttttttaatg ttgctaaggc
    11881 gaaattagat ttagatggat taaaacaggt aatgtttaat gattatttaa gacaaattat
    11941 atattttgga gagttagcag atttattaga agagaatgac tatgataagt tgaaaaacta
    12001 tttaaatgat agattaaata gtatagctaa ggatataaat gaaaaaaaag ttagtaagtc
    12061 tagtataaat actatagaaa aaattatgaa ggaaataaat aaaaacttta taaagaaaaa
    12121 taaaagcata gaagatataa aagagtatat ggatagttta gaagtatgtg aaatgtgtgg
    12181 tttatataag ggaatattag atgaatactc agaaagtaat tttgctccac ttggagtaag
    12241 caccaataat gctaggaata tgttttggaa tcaggcgtat gtaccatcaa tatgtgatat
    12301 ttgtaagcta atattgttct gtactccagc aggggctact tatacaagaa agaattattt
    12361 aattaatgaa gaaaatgagt tttatttatt tgttaacatg gatacttcta taaatgagct
    12421 ttttgaaaga aataatagtt taaaagctca aaaaagtgag tattcagatt ccaaagatga
    12481 aaatcctttt aatcagctta taaaaagtat agtagaagaa aatacattaa aaagtgaatg
    12541 gcaacttcgt aatatacttt ttgtggaatt taaagcaagt atagattcta aaaaatgtaa
    12601 aataaattat tttaatattc caacttattt agcaaaattt tttacagaca agtatgcaaa
    12661 taaaaaaata caaagtatct atgattacaa gcttaaatca aatatactag atttactctt
    12721 gaaaaatagg gacttgaagc atctaactaa taacatttta agaaataaag ttaaaaatga
    12781 tatggaaagc aacaacaaat caaatatatc aggaatagat tgttttagag tagtccaatt
    12841 aagagcatta ataaatagct acaaaaaggg ggtatataaa atggatagta aaaatttgga
    12901 gaagaatgat gaaaagctga gaataattta ttatttaggt tgtgatatac atgactattt
    12961 tgttaataaa aattctaaaa ataaaataga tggagtaagc tataaacttt taaattcagt
    13021 taaagtcgga aataaaagtg attttatgga tacaattata agagttttta tgtcagctga
    13081 aaaacagatt ccagcattta ttttagatat agaaattgaa aaagatttag actttgaatc
    13141 tataggtcat gcttttatat ctggattaat ttctggaaaa tatgaaggaa aagataaact
    13201 accaaacgaa aaggaggaaa aataagatga aaagagggtt aacatttaca gtaatagcac
    13261 aggctcaaag tttaaactat ggggaaggga taggtaatat atcagaatta aaaaaattaa
    13321 gtagagatga tggaaatata tatacatttg catctcgcca gtgtttaaga tatgacatag
    13381 tacgattagc agcagaattg tttaattgga atttacaggt tgtcgataaa gaaaaaggta
    13441 ctattcaatt taaagacaat ataagtataa gagaatcaga agaaatggat ttatttggat
    13501 atatgaaaac aaataaaaaa gatgagaaag ataaaaaagg aggttctttg actagagaag
    13561 ctactgtaag attaagtaat gcaatttccc ttgagccata tagaagtgac atggactttt
    13621 taaataataa aggattagca gatagaatag gagaacatcc taatcttgct aacatagagc
    13681 aacatttaag ttattataca tatacagtga ctatagattt atctaaaata ggtaaggatg
    13741 gagatataga acttgataat aaagagaaat gtagaagagt agtagaattt ttagaaataa
    13801 taaaagtatt gaatagaaat attagaggta gacaagaaaa tttatctcct ctatttgtag
    13861 taggaggagt atatgaaata gcaaatccat ttttcttggg tagaattaaa ttaaaaggag
    13921 ataaaaatgg atttaaaata aataagcaag ctatagaaga agtaattcaa ggtacttttt
    13981 taggaaaaga tttaaaagaa tttacctatg ttggaatggt agatggggta tttataaata
    14041 aagaagaatt taagggattg tttgaagata attttttaag tgtagataaa ttttttggac
    14101 aactagttaa agaagtaaag gaatattatg gggtgaatta atatgaaggt tttgaaatta
    14161 gatttatttc aagaaactgc atgctataaa aaaccatttg ctatgaagat tacagagaca
    14221 tatccactgc ctccatattc tacaataaat ggattaattc acaaaatatt aaatgctaca
    14281 gaatatatac catttaatat aagtgtacag ggaacatatg aaagtatatt taataattac
    14341 cagacaacat atttttataa aaaagatagt attacatcta tgccaatgaa tagtcatatg
    14401 ctattgaatg taaatttgat aattcatata ggtggggatt ttgatttatt ggaagaaata
    14461 tatgatagtt tattaaatta tgacgagcac ttatcattag gtagaaaaga agatttagta
    14521 agaattaatg atattagatt tgtagaagtc aataaatttg aagtagatga ggatatacaa
    14581 ttagatgatt atgaaaatta taagttatca gaatgtaata taagaatgcc tatatatata
    14641 ccaaaaacaa gtttacaaga tacagatata gatggtataa gttacagact caataattac
    14701 tatgataata atgctgtgga agataaaaaa agggtttgga ataaggtaga tagttattat
    14761 gttgaggatg gaaatactat atcaattgga gatatattat tagataatga aggagattta
    14821 ttatatttta ataatataaa ttaggaggga gagtatgtta tatgctaaat ctaatccagt
    14881 ggaaacactt agagaacata ctgatgaact tttaaaacaa atgaatgtat taagagaaag
    14941 ttacggaaaa aatataaata gcttagattt tctagaggaa gagatatttt ggcaattact
    15001 tgactttgtt atagaatttc atgatattgg aaaagcattt tcaccgtttc aagagttaat
    15061 aaaaagcaga atggatacta aaataaatga acctaaaata gtaactcatt tagaaaataa
    15121 tgtaggccat aattatcttt ctcctgcatt tattgattat agttatatag acaggaaaaa
    15181 aaataaagaa cttagagcag tattaaatca agttattgta tatcatcatg aaagagatat
    15241 ctttatagat aaagatttta aaaatttaat acaaaaaata ttagatgaag atttaataaa
    15301 taaagtttat gaactacagc gtaaatttaa agttagatat ccaataaaaa cagaaaaatt
    15361 gagtaaagta tatctacaaa gtgtagaaaa aagaatagat aaaaatcaca agtactataa
    15421 tttatatatt atgttaaaag gaatactaca tagactagac catagtgctt ctgctcatga
    15481 agttgtggaa tgcaataatg ttataaatat aggagaacag acagaaaatt atttaatgaa
    15541 agagtttggt agtttgagag aggctcaatc atttgctaaa tctaatagaa ataagaatat
    15601 aatactgatt gcatctacag gaatgggaaa aacagaaact gccttaattt ggatagataa
    15661 agacaaggca ttttttacac ttccattaag agtaagtata aatgcattat ttgatagagc
    15721 aaaaaatata gttggagttg gagaatcaaa tgatacattc ttaggtttgt tacattcaac
    15781 agcaatagat tatctagaag aaagtaatca agaaaattca agtgagattg tagatttagc
    15841 aaagttatta tcttgcaaac tgacattttc tacaatagac caaatattta aatttccttt
    15901 tttgtataga gggtatgaaa aagtgtactc aacattagca tattcaaaag tagtaataga
    15961 tgagatacaa gcgtattcac cagaaatagc agctgtattg gtaaaaggta tagaaatgat
    16021 acataagata ggtggtagat ttatgataat gacagctact atgccaacca tatatataga
    16081 tgaattaaaa aaaagaggtg taatgaatag taacttagct gaattgacat gtaatacaga
    16141 aaaaataaga cattgtgttt ctattgtaga aaattcaata gatgaaaact taggtaaaat
    16201 aatacaaagt ggaatgaata aaaaagttct tgtaatagta aatacagtta aaagtgctgt
    16261 agaaaaatat gagttaatag aagaaatagt taaaccaaaa ggaatagatg tcaacttaaa
    16321 tcttttacat tctatgtata tacaagaaga tagagcaaaa ttagaaaaat atataaaaga
    16381 atttgccaat agtgatagaa atggaatttg gattacaaca caattagtag aggcatctct
    16441 tgatattgat tttgatgagc ttcatacaga aaattcaaca cttgacagtc tatttcaacg
    16501 atttggtaga tgttatagaa gtcgtgagta tgaagagaat agcccaaata tatttatata
    16561 tacagaaaaa gctacaggaa taggtagtat ttatgataag gatattgtag aaaaaggact
    16621 tgagctactg aaaactttta taaatggaaa agaatgtgtg aagatgaaag aaaaatataa
    16681 ggtagaaatg gttaagatac tatactctaa agaaagtcta gaaggtacag cttttgaaaa
    16741 gagatttacc agtgctttaa atattttaga tactataacg ccatatagtt taggttctaa
    16801 agatgcacaa aatatactta gaaatattga aggatataca gtaattccag aggatatata
    16861 taataaaatt gaagaaactt taatcaaaga ttatgaagag ttgggacaag agcttataaa
    16921 tgcatatagt aatgatgata gacaattgat aaataaaata aagtctaaga gaaaaaaagc
    16981 aagaagagag ataattaaaa aaactgtaaa tttaccaata tataaagcta aacaaaatgt
    17041 aattgacata caggtgaaag gtcttgaaga tttaaaaata cttttatata aatatgatat
    17101 acacgaaaat aagcatacaa aacagatatt tggtaaaggt gtgcttataa gtaatgaaat
    17161 agaccaattt atttgatttt tatattaaca atgtggctaa aatttactaa agaaggtgat
    17221 tttgtgccaa tagatttaga agtattaaaa gttcaaggcg taaaaataaa ttattattat
    17281 gtatgtaaaa gaaaactatg gctattttct aaaggaataa ctatggaaca aaatagtagt
    17341 agagtattgt ctggaaagat agtacatgaa gattcatata aaagaatgaa aaataaagaa
    17401 atgttgattg atgatatctt gaagctagat ataataaagg acgagtatgt aaaagaagta
    17461 aaaataagtt caaagatgaa agaagcagat gaaatgcagt tatactatta cttatactat
    17521 ttaaagaata gtatgggtat agagaaaaaa ggaactataa attatgttaa ggaaaagaaa
    17581 caagaagaat tgatattgac agaagaaaaa gaaaaaatta ttgaaaacac acttataaat
    17641 ataaatgaaa taaatatgca gttatctcct cccaaaattg agaaaaaaca ttattgtaca
    17701 aaatgtgctt attatgaatt ttgttttgtg aaggaggagt aacaatgtat aaagactatt
    17761 atattataag taatggaaat ataaaaagga aagaaaatac gatttactat tacaatttag
    17821 aaggtgagaa aaaaatatta ccagtagaac aagttgatga tattcatata tatggagaag
    17881 tagatttaaa cacaaaactt ataaattaca taagtaaata tggggtgatg cttcatttct
    17941 acaattacta tggatattat tcaggtacat attatccaag gaagaaaaat gtatcaggat
    18001 tcagtttagt atgtcaatca gcctgctatt tagataaaaa tgaaagatta tacttagcaa
    18061 aatcctttgt ggaaagtgca tcataccata ttttaagaaa tatgagatat tacaaagttg
    18121 atgaaagttt aattgatact ataaaggatg aactaaatga tttgaatgat gtcaaagaaa
    18181 tatcagaact tatgggtaaa gaaggcagaa taagaaaaac atactataaa tcatttaatc
    18241 aaatattaaa agatgatttt gaattttata aaagagaaaa aagacctccc aaagactcag
    18301 taaatgctct tatgtctctt ggaaatagca taatgtatac gaatgtttta agtgagatat
    18361 ataagacaca acttgaccct acaataagct ttttacatga accatcaaca aagagatttt
    18421 ctttaagttt agatattgca gaaattttta agccaattat agttgacaca ataattttta
    18481 gcctgattaa taataaaaga attaataaga atgattttga atatcaagac aaaatttgtt
    18541 atttaagtga aaaaggaaag aagaaatttt tgcaagaatt tgaaaataag atgcagacaa
    18601 ctataaaaca tagaaatcta aatagaaaag tttcatatag aatgtttata aggttagagt
    18661 gttataaatt aattaaacat tttataaatg atgaaaggta caaagtttta aaggcgtggt
    18721 ggtaagtatg tttgttattg ttacttatga tattgttgaa gcaaggtcgt taaatagaat
    18781 tagaaggata cttagaaaat atttgacttg gacgcaaaat tctgtttttg aaggcaatat
    18841 tactgatgga aagttacata aatgtatttc tgaaatagaa aatattattg ataatagcga
    18901 ggattcaatc tatgtttatg agataaaaaa tcctaattca attaaaaaga aatgttatgg
    18961 gattgataag tattctgatg aaatgtttat ataggtttgc agtgagcgat atttatgcta
    19021 aaataggtgt taacagttgg aatataaggg attgaaggtg tatgataact attatcaatt
    19081 gcactactgc tcgctcactg caaattttga tgtttttatt gaattataat tgcttgattg
    19141 aagtattttc aatgtattca attataccta ttttggggtt ttatattaac taagtggtat
    19201 gtaaatttat aggaaaatga tgtcttagcg atatccattt ctcgttttat attaactaag
    19261 tggtatgtaa attagtttct tctatactag aatgtccaag catttcctgt tttatattaa
    19321 ctaagtggta tgtaaattga cctcaaatgt gtcactactt tctgtagcta tattgtttta
    19381 tattaactaa gtggtatgta aatgttttta tgctgcgaac tccatcatta ccttgctcat
    19441 gttttatatt aactaagtgg tatgtaaatt atagtgctta tcaacgtact tcaattctta
    19501 cattgactcg ttttatatta actaagtggt atgtaaattt gaaaaaatta tctcacgaat
    19561 ccgtcgagat gtcagtttta tattaactaa gtggtatgta aattgacgaa cattttcaga
    19621 acgatttggg gtctaaaaga gttttatatt aactaagtgg tatgtaaatt gaactctaac
    19681 cggttttatg caacaatata acgctgtttt atattaacta agtggtatgt aaatattgaa
    19741 agtcgtttca tacttcaaac taggagtaaa gttttatatt aactaagtgg tatgtaaatc
    19801 tctttttttc atctatatat ttttttattt tatgcggttt tatattaact aagtggtatg
    19861 taaattcaac tctttagata tataataaat tctaaataat tgagttttat attaactaag
    19921 tggtatgtaa atattgctat gtatctttca attttattta tcctcactcg ttttatatta
    19981 actaagtggt atgtaaatta gattttgttc aatccaaaca ttaccacttt taatagtttt
    20041 atattaacta agtggtatgt aaataaaact gcatctattg gtagttcatc agcagaatta
    20101 agttttatat taactaagtg gtatgtaaat atagtagatt ctataagaat atcagattta
    20161 ccatctagtt ttatattaac taagtggtat gtaaatcaaa agaactccaa tctggagtat
    20221 tttcatagac aagttttata ttaactaagt ggtatgtaaa tttcatattc cacaaatttt
    20281 gtttacactg aatagaaagt tttatattaa ctaagtggta tgtaaataca agaggctttt
    20341 cagaagtata tgtttttcta taatcgtttt atattaacta agtggtatgt aaatgaagaa
    20401 gaagccgaag atgatacaga agaagtacca gttttatatt aactaagtgg tatgtaaatt
    20461 ttataaaagc ttgatacttt tttcctcttc agaaatagtt ttatattaac taagtggtat
    20521 gtaaatctag atcttttgct tttaaaaaat gaattagaaa aggttttata ttaactaagt
    20581 ggtatgtaaa tttattaacc ttatcagaaa cttgaccatc ccaatcatgt tttatattaa
    20641 ctaagtggta tgtaaatcaa gctacaatat taagcgcaat taaaagaggt gcttgtttta
    20701 tattaactaa gtggtatgta aatcccttaa actcttcaac actttctttt aaccaattag
    20761 ttttatatta actaagtggt atgtaaattg ttgtggcaag actagttata caagagaagt
    20821 agcaggtttt atattaacta agtggtatgt aaatagaaaa tggtcaaacc tcattgtata
    20881 ctaagcttga tgttttatat taactaagtg gtatgtaaat ttggaaatta catacgctat
    20941 gctaatttcc ttttctggtt ttatattaac taagtggtat gtaaatagga taaagaaaag
    21001 actcacacaa gacacagtgt caggttttat atcaactaag tggtagataa gtagaatatt
    21061 agcaatatca acgagtattt agaaacttgt tttatattaa taaagcagta tataaaattg
    21121 tagaatcaac aatagcatat actaaaacat ccaccttata ttaactaaat catatctaaa
    21181 taaaatgcac ttacctataa acattataaa atcaatacaa aaatgaggtg aaacaaaatt
    21241 tatgataaag aaattaaata ataaagacat aaataaaatc atggaaatat gggaaaaaag
    21301 tacaatcaaa gcacatgact ttataagtaa agaatactgg caaaataact acaatactgt
    21361 taaaaacgaa tatataccta tatcagatac atttgtatat gatgatggag atgaaataaa
    21421 aggatttata agcataatag ataaaagctt tataggagct ttatttataa aacccaaata
    21481 ccaaaatcta ggtatcggag gtaaactttt agattatgca actaaaaaat ataaaagtct
    21541 aagtttagca gtatataaag ataataaaaa agcagttgtg ttttataata aaaaaggttt
    21601 taatatagta aaagaacaag taaatgaaga ttcaggattt aaagagtaca taatggaata
    21661 tagtaaataa tatgattaca ttctattaaa agaataatta atttattttc tatttgattt
    21721 ttataagagt aatttttaaa atagactata tgaagataaa gatatttatt atagatgtaa
    21781 gttaatcaga attgatatag ctacaaaaga ggaaaataaa attgtatggt gtatttcaga
    21841 tttaacaaat ttactattta aagataataa gtttgatata atattaaaga tactttaacc
    21901 tataaactat aaggtatttg aaagaatttt gaataattat ggaatgctaa taaaggtttg
    21961 ttaaaattta ataattatta gattatagaa aattgccatg aaattagttc agcaagaact
    22021 agtttcatag caattttaat tcttataagt gtatttattt ttacagattt aaaaaactta
    22081 tacagtatct aataatgtaa tcttattact ttagcctata aatatttaaa tcttaaaatg
    22141 ttctctttga gataagttta tttcagagtc acaatttcca caacagtaag atgttgagac
    22201 atctttaaat ttttcagtat tctcatcaaa gttcattttt ttctttgcaa taattcctac
    22261 cttagttaaa ttagaaccac aattattaca gttttgaatt ttacataggt tatatagttt
    22321 attaagtgta atatcttcta ataattcatc acaattacaa catctgatag aagaaacttc
    22381 actagacatt tcaataggtt cagcttcttt agaagaaaat ttatatgtta tgtcatttga
    22441 tactttataa cctgtatcaa atatattaga attacaactt ggacataagt actttggaag
    22501 atatatatct tttttttcaa aagtatcact actaatatta cagtttaatt catctaaaat
    22561 tggtctttca tctaggttat tacctttatt taagcttaga agataattat aaattttttt
    22621 atcttcattc tgttttgatg tatctaacaa atgctccatt atattagtgt attttttgtt
    22681 ttttgaaggc atgtttaaat ccagataatt gttttcaata gcaaagcata ctatgttgaa
    22741 atagttatat ttaactgcaa aaaataataa catttcatca aatactttat ctattatttt
    22801 gtcagaaata cttatccaaa aatctggtga ctctaagtaa actttcctac taagttcatc
    22861 taactcttca tctatattat tttcattaac tttcatatca tcacttcctt ttaaatatct
    22921 tgtgtataaa ctatttgtta ctatttttta tataaaataa aatcttatat aaaaatatat
    22981 catattataa tttacaagta tagtctaaat agagctgttt ttaagcaaag ttctataaat
    23041 gactattaaa atataaagta acagtataaa gtttacttat aaattaaacg taaacctaaa
    23101 tacttgtaat ggttgacaaa aaaacgtctt tattttatac taaaacaaag ctttaataga
    23161 ggctttgtat atgtacatat aaactaaatg aaataagaca tatgaaggga attataaaaa
    23221 tgaaaaatac taaagtaaat attcaagatt taactaaaat gtcaatatgt gtagcattat
    23281 tgtgtatatc atcttacata tatataccat tgccatttac tccagcagga gtaacagcac
    23341 aaacaataat gataaatttg atagctttga ttttaacacc aagacaagca tttagtacag
    23401 ttggtgtata tataatgata ggtttaattg ggattccagt atttggtgga ggtacatctg
    23461 gtattggaaa gttgttaagc ccaacaggtg gtttttattt tgggtttttg tttgcagcac
    23521 taattattag tttattaaaa ggacgaaata atgatattaa gagatatata ctaataacaa
    23581 cttttgttgg aatgcctatt atatatttta tgggaacagt atttatgtgc tattttaatc
    23641 aaatgacagt agaagcagca ctttttgcag cagtagtacc atttttaatt ggagatacaa
    23701 taaagtcggt tattgcatct tttttaggta ctaaactgaa caatgtactc agaagaaatc
    23761 tatgataaat ctataatata aggaagggtg taatgtatga aggaagtttt tatattagga
    23821 ggattgagaa gtcatatagg tctaaaaaat ggaatttttc aatttgttca acctgaatta
    23881 ctaggagcaa gtgttttaaa agatttaatt aaaaagtatg aaattgacaa aattgatgag
    23941 attatatgtg gaaatgcagt tgggacagga gggaatatag ctagattaat gactttaaca
    24001 gcaggagtgt caaatgaagt acctgctttt actgtggata tgcagtgtgc ttctgctatg
    24061 atgagtatag acatagcttt ttcaaaggtt aaatctggtc agtgtaattt aattattgca
    24121 ggtggttttg aaagtagttc tctacaacca atgcgcacat atcataagaa tgataagcga
    24181 tatgatacaa ataatccaaa ttatacagtt gctcaatttt ctcctgatga taatagtcaa
    24241 aatagtatgc tcgaaggggc ggaaagagta gcagcgttat atcaaattga gagagcagac
    24301 ttggattttt gggtaaagga aagtcataaa agagcaaaag aagcaagaga agaaaaaata
    24361 cttgaggata ttatatctcc tataaataat agtacctatg atgaaggtat acgtgataag
    24421 atgagtcaaa ggttattaga taggatgcca ccaattttag gaaaagaaac tattacaaat
    24481 gcagcaaatt catgtcttat taatgatgga gcttcattta ttataatatg ttctaagaag
    24541 tatttagaac atgtaaaaaa gaagcctaaa gcaaaaatta ttaatacatg cacaatagga
    24601 acagatgcaa ccttaagtcc aacatcagcg atacaagcaa tggataaact tttagagata
    24661 gaaagcctta attatttaga tgtatctgct gttgaattta atgaagcatt tgcagttata
    24721 gatgtgttgt ttcaaagaaa gtatccagag ttaatagaga gatataatat atttggtgga
    24781 gctttagcgt atggacatcc atatggtgct tcaggtgcaa ttattgcatt acatctttta
    24841 aaagcattag aaaaaactaa gggtagatat ggaatttgct ctatagctgc agctggtggt
    24901 ctaggttcag ctttactgct tgaaagggtg tagattatga actattatga acttttaaga
    24961 ataaaaaaag agaggcataa aaataaaaat tttttaatta tagatggaga aaaatatact
    25021 tatgaaaata tattaagtta tagtgaggaa ctaggaaaac aaatttcttt aggtgaaaat
    25081 atcccaattt taatatattc taaaaatata atgtttcagt tgattagttt ttttgctatt
    25141 aattattcaa aaaatattcc tattatttgt cattataatc tttctaaaaa agtattagat
    25201 gatattttat taaaaaataa tatttcaatc attatatctg atgaatctat ggacgttatt
    25261 gatttatatg atgataacaa taatgaagta gcaaaaaaag ttaatttttc tatttttaat
    25321 cctaaattta atatatatat gtatcaatat aagaacctta taaattattt agataaaagt
    25381 atttgtatgg gagctttatc ttcaggttct acaagtgttc caaaggtatt atatagaacg
    25441 tatgagagtt gggctggatt ttttcctata caaaatggta tttttaatat ctctggggaa
    25501 tcaatcttgt ttgttaatgg aacacttagt tttacaggga atctaaattc tataatgtca
    25561 gtattatatg aaggaggtag tattgtaata agttcaggtc ttaattgtaa atcatggata
    25621 aggacaataa aacaatataa tgtaactaac atatacctta tacctacaaa acttcaactt
    25681 ttggttaaac acttaaaaga accagtactc aaagtagtaa gtatttttac agggtctcaa
    25741 ttattatttg aatatactgc aagaaatcta aaaaaatata tgccaaagtc tgaaattatt
    25801 ttatactatg gggcaagtga attaaattat attacatatt tatgctatga tgaactaatt
    25861 gaaaaacctc taagtgtagg cagaccattt ccaggaatag atatatatat tagaggagga
    25921 aaaatttttg tgaatacaga atatgcagta tataatgcaa ccaaacctta ttctgtcaat
    25981 gatattggat attatgataa tgatggatac ttaatatttg aaggaagaag tgatgacatt
    26041 gtaaatattg gaggatttaa agttagttct gctaagattg aaaatgaagt taaaaaaatt
    26101 cctcaaattg aagatgcaat tgtattgccg tactcagaca ctataagagg aaatcaaatt
    26161 gtattatttg taataactat agacaaaatt acgaagaaag atttgttgat taaaatgaaa
    26221 gataatctaa tgaaaaatga aatcccaaag aaaattatct ttttaaattc atttccatat
    26281 acctcttctg aaaagataga tagattagca ttattaaaaa tgttataagt ataatattta
    26341 gtaattttag tgaaccaatg tattgataaa aacatattgt atatagtaaa ggaggcttac
    26401 aatatgtcaa atcaatacga tataactgtt attgggggag acctgcgaca agtgtacatg
    26461 gtaaaaaaac taattaataa agggtattct gtagtcactt atgggatatc aaatgaaatt
    26521 ataaatggaa tcgttggaaa atcaacttca ctagctgaag cactatccaa aagttccatt
    26581 attttatgtc caattccatt tacaaagaat caagttaata ttgaaaatac agatgattgt
    26641 cttgatgcta ctattgataa cttgctaatt aatttatctc ctaatcaaat attatttgga
    26701 ggtaacatac caactaaagt ttgtaaattt tgcgagcaac actctattca gatttatgat
    26761 tttatgaaaa tgaatgatgt tgctatttta aatgcagttg ctacagctga aggggctata
    26821 gcagaagcta ttaaaagaag tataatcaat atacatcaaa gtaactgttt agtattaggt
    26881 tatggaagat gtgcacaaat acttgcaaaa aaattatacg ctttggatgc aaatgtatgc
    26941 gttggtgcaa gaaataatga tgcaagaagt acggctaatg catttggata ttccagtatt
    27001 tctttaagtc aacttgatga aaaactttta caatttgatt atatttttaa caccatacca
    27061 gagtgtattt taacgaaaga aagattagaa aaagtatcac aagaagtaac tattatagat
    27121 atagcttctt ctcctggagg agtagattat tctgttgtta aagaagtagg gattaatgcg
    27181 actctttgcc ttgggcttcc tggtaaatat tcaccaaaga catctggtga gattcttgtt
    27241 aacgctatag aaaatattat aaatgaaaga agggattaga aatgagactt gaaggactta
    27301 caattggagt aggatttact ggttcgtttt gtacttatga taaaatattt atagagttag
    27361 agaatttggt taaagaagga gctaatgtac acactatatt ttcagatgta tcacaaaata
    27421 tcgattgtag atttggaaat tctgaagagt ttatgaaaaa agcatatgaa cttacaggaa
    27481 ataaacctat agttacgatt gaagaggcag aaccatttgg acctaaaggg attgctgata
    27541 ttataataat agctccttgt actggaaata ctgctgcaaa attagcaaat ggtattacag
    27601 attcaccagt attaatggca gcaaaaggtc atcttcgtaa tgataaacca ctagtaatat
    27661 caatatcaac gaatgatgct ctaagcttta atttcaaaaa tattggtatt ctccttaatt
    27721 ctaaaaatat atattttgta ccttttggtc aagataattg caaagcaaag cctaattcta
    27781 tgattgcaca tactgagcta ataattccaa ctatagaact tgctctagag aacaaacagc
    27841 tacagcctgt tataaaaagt ccacatcaat agaattggtt cttataatat tatgtattag
    27901 atacaatact agcaaagagg ctgtctcaaa atagagagaa gcctcttttt cattgttgaa
    27961 atgatgaaaa tatatttaat ttcatacaaa aaaatgcatc atgaactaaa aagtctattt
    28021 tgagctaatc tccgtaattt ttggtatatt aaaattattt acttaatcca atttttaaat
    28081 tagaatttat atcgttttga ctcttcaaat atcaatctaa ctgttgttga tacaaaagaa
    28141 gaggacataa ttaaaacaaa tactgatagt cctctaataa acaaattatc tacataataa
    28201 gttactattc caatacctcc aatcgttaaa attacactta taatcaaaga aaaaatgcta
    28261 attgttttta attttttcat gcttatcctc ctt
//
LOCUS       DACTZW010000050        28145 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.050, whole genome shotgun sequence.
ACCESSION   DACTZW010000050 DACTZW010000000
VERSION     DACTZW010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28145)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28145)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28145
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.050"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(<1..146)
                     /locus_tag="JAM15_11565"
     CDS             complement(<1..146)
                     /locus_tag="JAM15_11565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006785398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HAT6798890.1"
                     /translation="MTELMIISGLVLLICITSSKVLYKFGVPILLIFILLGMLFGSDG
                     MVGI"
     gene            complement(629..1537)
                     /locus_tag="JAM15_11570"
     CDS             complement(629..1537)
                     /locus_tag="JAM15_11570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2268 domain-containing protein"
                     /protein_id="HAT6798891.1"
                     /translation="MNIIEIRSDKIYKKIMDAPINKKEDIYRYELMKPFEFKWKCMNV
                     PIVARQKGGYDVIIASEMLGVLSPKDIDEKQKKNINVLSADKIWGTCKETIENSINAF
                     IKEGYDLNIKDYKYSILLANPNSPYTILSDGYWGDGGIPGYIFLSLVPNEYTINRLPV
                     LIAHECNHNIRFQFIEWNNNITLEEMMINEGLAENFATWMFGEEMLGPWVSRTDIETL
                     NTYIKPIIKSALKETGFQNITSYLYGDDIAKMQGYFPVGLPYCAGYACGYYMIKYYLE
                     KTNKSIIEATLLPYSEIIEAVKEFWE"
     gene            1808..2185
                     /locus_tag="JAM15_11575"
     CDS             1808..2185
                     /locus_tag="JAM15_11575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008790757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAT6798892.1"
                     /translation="MLTPYLIFNGTCEKAFNFYAEAFGGGKTIFARLDSNPNNPIMHA
                     SVTFTKYEGCIMGADTDKPVVISGMAICVVLPSREAIEEISVKLAEGGTLVQEFLPHP
                     PPHQNDGAAEVLDRYGYTWYLST"
     gene            complement(2341..2790)
                     /locus_tag="JAM15_11580"
     CDS             complement(2341..2790)
                     /locus_tag="JAM15_11580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAT6798893.1"
                     /translation="MKSGIILEMKQINSTEYDEMLQVWESSVRATHDFLTEKDIESLI
                     PLVEIGLKEVENIVCIKDNDIIKGFIGIDKDKIEMLFIEDKYRGNGIGKKLIKYAIDK
                     YNVKYVDVNEQNKKAVGFYIHLGFKVFDRSEIDGQGNPFPILHMKLI"
     gene            complement(2968..3372)
                     /locus_tag="JAM15_11585"
     CDS             complement(2968..3372)
                     /locus_tag="JAM15_11585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798894.1"
                     /translation="MSYQNYKCERDYVYDDYKYNKCNKCYNDYEEMTHVHEYSESVKL
                     AEECEDRHNHRAAGVTGEAIPINGGTNHVHKINDNVDFLDHFHKICVTTGPAIRIPGT
                     DKHIHLICGETTVNDGHCHKFLFTTQIEAPLV"
     gene            complement(3485..4351)
                     /locus_tag="JAM15_11590"
     CDS             complement(3485..4351)
                     /locus_tag="JAM15_11590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HAT6798895.1"
                     /translation="MIDIHKNIYDNKLFEELKIDCKKCFGLCCVALYFSASDGFPIDK
                     ESGKPCINLQPDFKCSVHNSLMKRGFKGCTAYDCFGSGQKVAQVTYKGIDWMQSSELT
                     NQMSEVFLIMRQLHEMLWYLKEASVLNISDTIKSKIDLIIEETEKITNMSPEQIIDLD
                     IISHRTKVNLLLSQASESVMGKVKSFIKTSTLKNMKKLSKNIDLIGADLRKINLIGAD
                     LRGRFLIAANLRSTDLSGANLIGADLRDCDIRGANLENSIFLTQLQVNTAKGDSSTKL
                     PASLIRPKYWEK"
     gene            complement(4921..5265)
                     /locus_tag="JAM15_11595"
     CDS             complement(4921..5265)
                     /locus_tag="JAM15_11595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HAT6798896.1"
                     /translation="MENLPNCPKCNSEYTYEDGTLLVCPECSHEWALGLGAEEDSNII
                     KDVNGNVLNDGDSVTVIRDLKVKGSSSSIKIGTKVKNIRLIHDSSDGHDIECKIDGFG
                     AMKLKSSVVKKA"
     gene            complement(5454..6071)
                     /locus_tag="JAM15_11600"
     CDS             complement(5454..6071)
                     /locus_tag="JAM15_11600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6798897.1"
                     /translation="MISLINISKKFKDKSIIDKFNLEISKGEFVAITGNSGSGKTTLL
                     NIMGLLEKPNSGDIIINNIKNPNSKQIRILQRDFYGYLFQNYALIENENVENNLKIAL
                     KYQKNINHNEKINYALESVGLRKYNKKKIYELSGGEQQRVALARVILKECEVIFADEP
                     TGNLDKKNRDIVFDILKNLNKNGKTIVFVTHDLELSEQADRVIKL"
     gene            complement(6076..8247)
                     /locus_tag="JAM15_11605"
     CDS             complement(6076..8247)
                     /locus_tag="JAM15_11605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HAT6798898.1"
                     /translation="MKKIIYVLFTIELLIVSLLGLNIVKDNEINNILYNDTTSISVMF
                     KDYKKLNKNYSKWIKDIADENNVAISKYVFNNNEKLSIYTTDTSLNNNIKLKSGKFPN
                     TNSNEFISNINTNNSNNSNQVGKFSTMSKDISILIRDFGKISEVGESGILYISTQNED
                     TINKILRELNVDRSIFVARLHDRYVNSNLYLNPSIIRDLILIILCFLATIIHYSISVS
                     REASILRLNGYSKLDIIARVIKNILRIMILSSVTALLIYIIYILKLNIGVRACLYFAM
                     FSIICILINILISILIVGFNSRSSKYVLSLNGKKSYGFVNIMHFTLKIVFVSFLILSI
                     NNCILNYNMLQTQLGNLSEWDKAKNVYNLTLKDTGEQSLGKEEVIKNAKIKGFYKNLV
                     EEKDAFLIDSTNFEKLEDGSYMYEINSKGKNPEVSQYGKNIKINKNYLKVNPIYSNGK
                     EIFNLIDYDDKTINLLVPKKLQVHENEIKKEFRELFYFEKIEVENMYNKELNRELNKT
                     KKSDLNVNIIYVDNNQSYFTYNSLVMDDNRNLIDDPIAIIDIDNIDDSFYLSYISRCV
                     YFNSKKLDALADISNIIEAQGVEAHIQSLHAVYNEYGLEINKLEKYLNSEIFTIIIIA
                     ISNLMITYNIVASYYERNKYKLYIKKIFGYSTTARSMLLIVSLILTNIIPIGIISTRV
                     DLSNNIILFGLLILVIEVIVSIVLDKIISNSSFNKIIKGEH"
     gene            complement(8662..9294)
                     /locus_tag="JAM15_11610"
     CDS             complement(8662..9294)
                     /locus_tag="JAM15_11610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketohydroxyglutarate aldolase"
                     /protein_id="HAT6798899.1"
                     /translation="MKKMNITKRMSECGALAIVREENLNRACEIAEGCIKGGITVIEM
                     SYTLNNAGEIIQGLNKKYGEILCVGAGTVLDSETARHAILHGAQFIIAPNYNEGVAKI
                     CNRYQIPYAPGCTSLTEAVDALSLGATFIKAFPISDFYGPKLVKVFKTPIPDMPVLAS
                     GGINLENLHIWLENGVDVCGFGGLLTKGTIEDITENAKKIREIIKNIREI"
     gene            complement(9400..10305)
                     /gene="dapA"
                     /locus_tag="JAM15_11615"
     CDS             complement(9400..10305)
                     /gene="dapA"
                     /locus_tag="JAM15_11615"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HAT6798900.1"
                     /translation="MKYKGIICAMITPFDEKQNINSQATCKLIDYLIEKGIYGLFILG
                     TNGECHVLTDDEKVEFAKIVINHTNNRVPVFVGTGGNSTREVIDLSKRMEAIGASALS
                     IITPYFVTPTQQELILHYKTIANSVNLPIIMYNMPGKTGINIEPESVRELSKIKNIVG
                     IKDSSGKLDNMKAYIEVTQNENFSVFSGSDSLILDSLKVGSQGAVAATTNFLTEIGIS
                     IYENFMKGDLEEAQKAQSSIEELRRILKLGTIPSVMKKTIVLNGINVGTARLPVTEPT
                     GEVLEEIKRVVENYRTILNKSSENR"
     gene            complement(10310..10909)
                     /locus_tag="JAM15_11620"
     CDS             complement(10310..10909)
                     /locus_tag="JAM15_11620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAT6798901.1"
                     /translation="MENTLSEFLDNISNELSEFIASIDETSINKACELILEAEKNHGR
                     VHVTGIGKPGHVSGYISSLLSSTGTSAYILHGTEAVHGSSGQVVEGDVVIAISNSGET
                     QELKATLKTLKVNGAKIIGVSGNESSFLKNISDIFLFAGVKQEGDCLNKAPRASILAE
                     TIVLQSLSVVLQYAKGLNTQQYLKWHPAGSLGKSIREGI"
     gene            complement(10967..12238)
                     /locus_tag="JAM15_11625"
     CDS             complement(10967..12238)
                     /locus_tag="JAM15_11625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HAT6798902.1"
                     /translation="MEFIISLLSTPAVLLGVVACIGLILQKKSAVEVFTGSSKTLIGF
                     LIFGIGASAMTGALQNFNKLFQHGFGITGVIASPEAATALAQGTYGFAVSCTLILGFI
                     LNLVFARITKFKNIFFTTGHSLFFSCVLVLIMKAHGFDNTITILIGGTILGFMSAALP
                     QFCQPFMRELTGGDEQAIGHFNMIGYGLSGYIGRLFSKYKDDTTETIEFPKWLSIFRD
                     FLMGLSIVMLILFYIATLKAGQAFTQEIAGSTHWLVFPLIEAFTFVAGMSILMSGVRM
                     FLAEITAAFVIISEKYIPGSRPALDVPTVFPYAPNAVIIGFISAYAAGLLAIAIMASF
                     PSIFPVVIIPAAHICFFSGGTAAIFGNTSGGWRGAIAGSFVVGLLLAFLPVILYPVYG
                     TLGIEGATFPNIDYNVVGSILHNILQFIKPI"
     gene            complement(12265..12552)
                     /locus_tag="JAM15_11630"
     CDS             complement(12265..12552)
                     /locus_tag="JAM15_11630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAT6798903.1"
                     /translation="MYKILIACRAGVGSSLMLKIKTQQIIKENNFPIEVEHGSLDSLN
                     GFNGDAVETLIDVAEELKNKNLKFDIIGIHNIVDRNEIKTALEKFLASKEG"
     gene            complement(12567..14648)
                     /locus_tag="JAM15_11635"
     CDS             complement(12567..14648)
                     /locus_tag="JAM15_11635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HAT6798904.1"
                     /translation="MDKEIVSILQILLNSTLITTNGLQEESNSSKRQITYRINKINDM
                     LKVKNVPLICLRADKDIIVRKETKKAIKEILEKNYSKNTYYFSKTERLLYMYLMLFIN
                     MEDISINHFINSIKVSRSTVNLDFKDLIPELEKKNIKVKNNRINGYYIVGNEMEIRRV
                     LIKNIIETLSNEKSSRVFDIFIKEYNLDSFEEAKKIILKLIKKYEITFVEDRLIEFIY
                     IFIFLKARMYSTRIVTQENVDIPNISVMSSMKEYKFAKELLEVYGSEDKIKPYNIMYI
                     SAWILGISVGNYEEDTEDKDVISKIVNKMMTKFGYLSGVYYISQEKIFKQLYSHFRPA
                     YYRLLFKLPIYNPICEKVKEEYKLVYRIVSNAMKEFCGLFGEKIQEEELAYLTMHFAT
                     LFSNKKEFDGFRKRIALIVCSNGVGSSAILHAELTNLFPDLHFIPMSESVGLENISEP
                     VDIVFTTNYNAEGLKTDVPVIKVSPVMTTKEKYKITREVYIQLGDIYLRQPKIDEVMD
                     IIKKYANVTSESILSSELLAYFTQIENFTSKEGEGPMLSEITNETLVKIKVKAKNWEE
                     AIRQSASVLVENNKVTEGYVDAMINSAKASGPYIVITKHVALPHARPEAGSKEIAIGI
                     ATLDSPIEFGNNENDPVKYVFCLSAIDNNSHLRAMSELVELLEEDEFFKVLDSAKEAK
                     EIIDFIKTHEL"
     gene            complement(15221..16069)
                     /locus_tag="JAM15_11640"
     CDS             complement(15221..16069)
                     /locus_tag="JAM15_11640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase"
                     /protein_id="HAT6798905.1"
                     /translation="MGFEFKIMRSLIYVGLAKEEYRPKLMDWLYRHHIPDSISTFGPY
                     CTKYAFYQAYPTPNEGERFGARKMQLTEHYWLVDEHMPEMANRIMTEYMPMDVLRWQG
                     CIPDVENKRVHENAESGDAGRAVGGDNGCPPFIFAFVPINWEEDFRGKGRTVQDGPNY
                     RWQFMIKYPDGISKEEGEKWFYDEVVPYFTNCCYVNRFVSSKIMINYGATAFDRVSEL
                     WFEGEEEWYKAVVEETKSFIKKPEWAQEEEFPYLKPQFNIASVFLGDIATMDAYSQYR
                     GYIPMR"
     gene            complement(16107..16619)
                     /locus_tag="JAM15_11645"
     CDS             complement(16107..16619)
                     /locus_tag="JAM15_11645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HAT6798906.1"
                     /translation="MDRKKKEILTLSMGIALLPPLWAVLAPYIGIKTGAVALICAGLY
                     VTNGNKQKDGLKIMFGFWCGDLWAVLAILIMGYMNFNQNLELFLTLSILGFFAVVIAS
                     LFEKIIFLPSWLCGWAIGLTIMTGENIINLQDICIQIAVAMAVGVWYVGAGVDLFTIY
                     ILSKDKKKGN"
     gene            complement(16612..16836)
                     /locus_tag="JAM15_11650"
     CDS             complement(16612..16836)
                     /locus_tag="JAM15_11650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798907.1"
                     /translation="MNEKPNFKQIEIILAVIFLVLTYYKIGLTPAFIVIFIPLYLSYF
                     AVSMIVNQIAIKLLEIRQAREATNYNIGNG"
     gene            complement(16896..17849)
                     /locus_tag="JAM15_11655"
     CDS             complement(16896..17849)
                     /locus_tag="JAM15_11655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HAT6798908.1"
                     /translation="MKILGISFGTKNGNNDTMCKVALKGAKEAGAEVEFIQMSSINIK
                     HCTGCCACVKTLLSGKGSMCVLKDDFEWLLDKMKDADGIVVSDPIFEEGASGLFHTIM
                     DRFGPRADRGNNIIGTKVAEAIGGKIPDSRMLNDKVISFMGIGGSDWGTRVQCEHAML
                     ALIPMWKVIDNAWFPWAKELVMDDTRLVQVHQIGLNIVEAAKDFEKASYQGEEGVCPH
                     CHNRLFYLESGTKKAICALCGIVGELDTISGKTIFSFPEEQLGHAHDTLPGKFIHGDD
                     IKKMEGHYAEVRKTQEFKERKTSYNFIEPLTKEKQAGVSLG"
     gene            complement(17877..19265)
                     /locus_tag="JAM15_11660"
     CDS             complement(17877..19265)
                     /locus_tag="JAM15_11660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798909.1"
                     /translation="MEDKFYAKGNGNNGYIKNLEVCSFNNLDGTCGMFQMALYKRDEK
                     YYLYGCCFGGNKKNGVMISDITDPYNPQFIKHFQMLDPKEYPTTTTPKIQIADDLMIV
                     AMSCGSGPGALVDQAKLANIKCEAGIRIYSLKEDPLNPKFLGYWDCGLKHVMGVHRFM
                     YNGGRYVHLSSDCVGFEGLIYRVIDIINPNNPVEIGKWWRPDQYADGYPNRTFDAGAP
                     HCPEFMDKGWLHGPPFVRDGKAYCGYGGAGLVVLDVEDLTRPRCLGELPFMPAFSSRL
                     AGARTHTALPLPGRDLVVVQNEGERFQFFKPDNITDVQAMNNIHMVDVSDPTKPTLIA
                     QFPYPEVPKDFPYPNFNVAGLGKAGPFGPHNLHEPMDNKPWLEQRGDRVYCCYFHAGL
                     RVYDVSDPYYIKELAYFIPPNPNKTPEESYFPGFPGPRLAVTEDLIVDDRGYIIIDAL
                     DDGFYILKMKED"
     gene            19538..20419
                     /locus_tag="JAM15_11665"
     CDS             19538..20419
                     /locus_tag="JAM15_11665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAT6798910.1"
                     /translation="MNTKQLEYFISVAENLSFTKTAEKFYISQTAVTQQIKALEEQIN
                     VTLFTRSKRHVELTPAGKVFLSEARTIIKNINDAIAKTQQFAHGFFGTLSIGTLIGYE
                     KNKLQQYLKEFSNTYPNISMDICTNEITELLNLVKNNSMDLAFVINPENQPLKDFEYK
                     TVERYSLVALLPPGHPLYNEDSIDLIELQHDKFIFVKETGDEYGQKSMIQNRYREAGF
                     VPNVVQRSNNLNTIESLVSSNMGISILPSFCVTDTMIERDIAIVPIKEVENRIEVVVV
                     WNKKNTNPALEKFISII"
     gene            complement(20606..21598)
                     /locus_tag="JAM15_11670"
     CDS             complement(20606..21598)
                     /locus_tag="JAM15_11670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HAT6798911.1"
                     /translation="MNILAFGEIMMRLSVPDYKFLTQTNELNYIITGTGLNILSGLKN
                     FGHNTYMLTKLPNNNVGKASSANIRKLGVKDDFITYGGNHIGVYFLENGYGERPSEVT
                     YLNRLNSSFCESKLQDYDIDKCLEEMDIVHICGIAMQLTDSVKEIALELARKSYEKGI
                     KVFFDFNFRQSLNPERTYDDLVNEYKKILPYCHGLFASYRDINKILNIDSLNIKSSSE
                     LIKKEYDIDIVAGTMRRFDDMNNRFIKGYISNDDGYFESREYKLEIYDRVGAGDGYVA
                     GIIYSYLENMKSEDIVEFGVASSVLAHTTYGDNFLVSTGHVLRLMNNEKIDILR"
     gene            complement(21603..22343)
                     /locus_tag="JAM15_11675"
     CDS             complement(21603..22343)
                     /locus_tag="JAM15_11675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KDGP aldolase family protein"
                     /protein_id="HAT6798912.1"
                     /translation="MNCIPQYYKNRVCLNVLAGSIKNAKEVYDACDGHVLVGVLSKNY
                     ITVEAAIEDMKKYSKEIDNAISVGLGAGDPNQSNMVSQISKELQPQHINQVFTGVATS
                     RALLGQNDSIINGLVSPTGKPGFVKISTGPLSSKEKDGIVPIETAIAMMKDMGGSSIK
                     FFPMGGLKTKDEYIEVAKACAKHNFYLEPTGGIDLDNFKEIVQIALDAGVEKVIPHVY
                     TSIIDKETGDTKVEDIGVLYKIMKELLG"
     gene            complement(22408..23517)
                     /locus_tag="JAM15_11680"
     CDS             complement(22408..23517)
                     /locus_tag="JAM15_11680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
                     /protein_id="HAT6798913.1"
                     /translation="MSSIFEKYSVRRVINASGKMTILGVSTVDKEVIEAIGEGCKNFF
                     IIEELVNKTGEYIANLLGCESALIVSSASAGIAQSVGAMIAKDDMSLVYNVNNPKKQV
                     KREIIIPKGHNVDYGVPVEVMIRLGGGEVVEAGYANMCNKEHIIREINENTAAIMYIK
                     SHHCVQKSMLSVLDAVQVAKEYNLPLIVDAAAEEDLNVYYELGADLVIYSGAKAIEGP
                     SSGLVIGKKKYIDNVKLQSKGIGRAMKIGKENIVGLTCAIERYISNDKVTLKEMEDKL
                     NPFIDKINTINGVSASITRDSAGREILRGEIDFNEDIINKSTQQIINELRSGEIAIYT
                     RDYKANEGKIEIDIRSVTGSDLDTIYNRIKNIVES"
     gene            complement(23535..24668)
                     /locus_tag="JAM15_11685"
     CDS             complement(23535..24668)
                     /locus_tag="JAM15_11685"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HAT6798914.1"
                     /translation="MKIDILIKCGKTVDKSIIDIAILDDKIIEVKNHIDDSKYQAKQI
                     INLDGEKFISAGWIDIHTHCYERLDLYKDYPDEVGIKSGVTTVVDAGTTGALDIGEFY
                     EDTKKYKTNVYALINIAKQGITSQDELSNMMNIDEYELKNAVRKYKDFVVGIKARMSK
                     SVVISNDVEPLKVAKRIKNELNLPMMVHFGSSPPTIEDIFDYMEKGDILTHIYNGKPN
                     GILRGNEVKKEIIEARERGIILDVGHGTESFSMDIAMKSKDAGIFPDTISTDIYIKNR
                     INGPVYNLSTTMEKFIYMGYSLEDIIDKVTKNAADAISLKNKGLIKEGYDADLTIFDV
                     VNEEKELQDSLNKSVITSTSIKPRAVVVNGEYLNIGKSIEENE"
     gene            complement(24670..25764)
                     /locus_tag="JAM15_11690"
     CDS             complement(24670..25764)
                     /locus_tag="JAM15_11690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAT6798915.1"
                     /translation="MERRLGISVYPEHSNMEDDKAYIKMASKYGFKRIFMCMLSITRP
                     KEEVKKHFKEIITYARELGFEVILDIAPNIFDILQISYDDLTFFSELNASGIRLDYGY
                     DGSKEAMISFNPYDLKVELNISNDVAYLDNIITYKPNVNNIYGCHNFYPQRGTGLPYD
                     FFVRCLNRFKKYGIRTAAFVNSKYATIGPWNINDGLCTLEMHRNLDIATATKHLFATG
                     LIDDVIVGNAYASEDELKRMSEVNEYQVVFNVVAEEKTSEVEKIIMVNEQHFRRGDIT
                     NQVARSTEVRKKYAKENFPKHDNKNIFKRGDVVIGNDDFGKYKGELQLILQDCTDERK
                     NKVGRIKEDEIILLDFIEPWSKFKIILEGE"
     gene            complement(25901..27202)
                     /locus_tag="JAM15_11695"
     CDS             complement(25901..27202)
                     /locus_tag="JAM15_11695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAT6798916.1"
                     /translation="MEKFASFLERKIMPVAAKISNQRHMRAVRAGIIATLPLTIVGSF
                     FTILLNIPIDAYMDFIAPFKAILDIPFRYTVGFLSLYATFGIASSLAKSYDLDTTGVG
                     MLAVMAFLVSTIVPTQVVEPVGGVIEAGRWMDMAKLNSPSLFGAIVTSLITVEIYRFM
                     KEKNITIKMPAGVPVEVSNSFTALLPTAVILMLFWVIRHILGFDISVALSAMLSPLKG
                     FLSGNSLGGGLLTVFLITLFWVLGIHGPAIMGPVIRPIWDMSIAENITAFTEGVSAHA
                     MPNIFTEQFLQWYVWIGGAGATLALVVMFMFSKSQYLKSLGRLGFLPGLFNINEPIIF
                     GAPIVMNPILGIPFIIGPIIMTILSYVLTITGVIPMMVARLPFAMPAPIAAVMSTNWS
                     ILAGILVLINFVISFAVYYPFFKVFEKQQLQREQEEMSENL"
     gene            complement(27426..28127)
                     /locus_tag="JAM15_11700"
     CDS             complement(27426..28127)
                     /locus_tag="JAM15_11700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAT6798917.1"
                     /translation="MLKNQPLYIQVVDILKQKILNNEYKIDENIPTERELEQEFGVSK
                     ITIRKAIEILESEGYVEKKSGKGTKVISNSLFNKLSKAESFSSILLSKGHKLSKETIS
                     IEKIINDTHSQVFSIFGENCSKITRMYYLDSKPYIFFTHYIPFDENLTVESFNNESSL
                     YMYLYRRNINITRFEDEFFIEESELEVSKALNLAKDILLGRKRKTYDENDNIVELSFA
                     RYNTEVQNYVIKYEI"
BASE COUNT         9169 a         4991 c         3083 g        10902 t
ORIGIN      
        1 tagattccta ccattccatc agacccaaat aacatcccta gtaagataaa aatcaataat
       61 attggtactc caaatttata caataccttg ctagaagtta tacaaatcaa tagtactaac
      121 ccacttataa tcattaattc tgtcatagca tcaactccat ttcatataaa ttttgtagat
      181 taatttgcat ctacaatttt attacttatt caaatataac atgacataaa ttttataagt
      241 tatggtacat aaagttcaac aaaaatttca caatacatta aaatgtgagt gttatactta
      301 aatttatata tttgttttaa ttatattcat ttaatattta taatttgaat tttttttatt
      361 aatatttcat tttttagttg attgtttaat atatttcatt ttttatagta attttatata
      421 taactacgaa atataaagta attagataag taacaagaaa ctaacatgta atgttaggta
      481 ctctagatat gaaatcttaa aacttttaaa tattgaaata tttctttata tatattattg
      541 tatatttctt ataaattatt gtcaatttat tttttcttaa aaataaaata attgcataat
      601 ttatttcaaa ttatgcaatt tataaatttt attcccagaa ctcttttact gcttcgatta
      661 tctcactata aggcaataaa gtcgcttcga ttattgattt atttgtcttt tctaaataat
      721 acttaatcat ataatatcca caagcatatc ctgcacaata aggcaaccct actggaaaat
      781 atccctgcat tttagctata tcatcaccat aaagataaga tgttatattt tgaaatccag
      841 tttcttttaa agcacttttt attattggct ttatataagt atttaatgtt tcgatatctg
      901 ttctactgac ccaaggtcct aacatttcct ctccaaacat ccatgttgca aaattttctg
      961 caagaccttc atttatcatc atttcttcta atgttatatt attattccac tctataaact
     1021 gaaatctaat attgtgatta cattcatgtg ctattaatac tggtaatcta ttgatagtat
     1081 attcattagg aaccaatgat agaaatatat atccaggaat cccaccatca ccccagtatc
     1141 catcacttaa tattgtataa ggactatttg gattcgccaa taatattgaa tatttatagt
     1201 ccttaatgtt taaatcatac ccttctttta taaaagcatt tatagagttt tctatggttt
     1261 ctttgcaagt gccccaaatt ttatcagcag ataacacatt tatattcttt ttttgctttt
     1321 catcaatatc cttaggcgat aaaaccccta acatttcact tgctataatt acatcatatc
     1381 cacctttctg tctagcaact attggaacat tcatacactt ccacttaaat tcaaaaggct
     1441 tcatcaattc atatctgtat atatcttctt ttttgtttat tggtgcatcc attatcttct
     1501 tgtatatttt atctgagcga atttctataa tattcatatt taccatctcc tttaagacaa
     1561 agtatataca attacgtagc gtcaatgtca atatacattt tttataatgt caccttaatc
     1621 tttttattat attttatcct gtaaaccttc cgtacatata acattttttt aaattaataa
     1681 atttgtataa tataataata aaaaattata tacttcaagg tttccctatg atacaattta
     1741 ctaaatcata atttagatta tcaggtgcaa ctataaatta ttctatatca aggaggatat
     1801 attggtcatg ctaactccat atttaatatt taatggtact tgtgaaaaag catttaattt
     1861 ttatgctgag gctttcggag gaggaaaaac tatatttgcg cgattagaca gcaatccaaa
     1921 caatcctatt atgcacgcaa gtgttacttt cacaaaatac gaaggttgta taatgggtgc
     1981 ggatacagac aagcctgttg taatttctgg catggcgatt tgtgttgttc taccatctcg
     2041 agaagcgata gaagaaatat ctgtaaaact tgccgagggt ggtacacttg tacaagaatt
     2101 tttaccacac ccaccaccac atcaaaatga tggcgctgct gaagtacttg ataggtatgg
     2161 gtatacttgg tatttaagta catagtaaaa ataaaaaaac tacatctaat aatcataata
     2221 tagaacagat aaatttcaat ttaatagtgt agtaaaaaag tcgtgtccta agactgtcac
     2281 gacttttatt tgtataaaaa tttaagtaaa tatttttgcg aataagtgag aagtataact
     2341 ttaaattaat ttcatatgta gtattggaaa tgggttacct tgtccatcta tttcagacct
     2401 atcaaacact ttaaatccta agtgaatata aaatcctaca gcttttttat tctgctcatt
     2461 tacatcaaca tattttacat tgtatttatc tatagcatat tttattaatt ttttaccaat
     2521 accatttcct ctatatttat cttctataaa gagcatctca attttatctt tatctattcc
     2581 tataaagccc tttattatat cattatcttt tatacaaact atattttcta cttctttaag
     2641 tccaatttca actaatggta tcaaagattc aatatctttt tctgttaaaa aatcatgcgt
     2701 tgctcttact gatgattccc agacttgcaa catttcgtca tattctgttg aatttatttg
     2761 tttcatttca agaattattc cagatttcat aaaatttcct ccctatatca cttttaattg
     2821 tataacactt ttttatacaa aacttagaaa ggactacgaa ggttaagtat catagtccta
     2881 attaagttta aatattatct attatatatt tttaacattt attatatact ataatctagc
     2941 aaatttacta caataatcca tatcagttta tactaaaggt gcttctattt gagtagtaaa
     3001 aaggaattta tgacaatgac catcattaac agtagtttct ccacatatta agtgaatgtg
     3061 tttatcagtt ccaggtattc taattgctgg ccctgttgta acacatatct tatggaaatg
     3121 gtcaaggaaa tctacattat catttatttt atgaacatga tttgtacctc catttattgg
     3181 tatagcttca ccagtaaccc ctgctgcacg gtggttatgt ctatcctcac attcttctgc
     3241 taacttaaca ctttctgaat attcatgaac atgtgtcatt tcctcataat cattatagca
     3301 cttgttgcac ttattgtatt tataatcatc atacacataa tctctttcac atttataatt
     3361 ttgataactc atttttatat ctctccctat attatattaa gaaattcttg taaagaatct
     3421 ctaatgtata atatgaatta aagtcaaaaa agttcatatt ttgtaaaatt atgtattaat
     3481 ttaattattt ctcccagtat ttagggcgta ttagtgaagc tggtaacttc gtactagaat
     3541 ctccttttgc agtatttact tgcaattgtg ttaaaaatat actattttca agattagcac
     3601 ctctaatatc acaatctctt aagtctgctc ctattaaatt tgccccactc aaatctgtac
     3661 ttcttaaatt tgctgctatt agaaatctac ctcttaaatc tgctcctatt agatttattt
     3721 ttctaaggtc tgctcctatt aaatctatat ttttacttaa ttttttcata tttttaagag
     3781 tagaagtctt gataaatgat ttaacctttc ccatcacaga ctcactcgct tgtgataata
     3841 ataaattaac ctttgttcta tgtgatatga tatccaaatc aattatctgt tctgggctca
     3901 tattagttat cttttcagtt tcttcaatta ttaaatcaat ttttgatttg attgtatctg
     3961 atatatttaa tacagatgct tctttaagat accataacat ttcatgtaat tgtctcataa
     4021 ttaaaaacac ttcagacatt tgatttgtta gttctgatga ttgcatccag tctatcccct
     4081 tatatgttac ttgtgctact ttttgacctg aaccaaaaca atcatatgca gtacaccctt
     4141 taaaacctcg cttcataaga ctattatgta cagaacattt aaaatctggt tgtaaattaa
     4201 tacagggttt tcctgattcc ttatcgatag gaaatccatc tgaagcagaa aaataaagag
     4261 ctacacagca aagtccaaag cacttcttac agtcaatctt tagctcctca aataacttat
     4321 tatcatatat atttttatgt atatctatca tattttttct cctcttaagc tttattttta
     4381 atattatatt atctataact aaatgataat caagtccctt atttaacagt tcttattctt
     4441 aattataatt taaggtatta tttattccaa tagcatacat aagtttcttt atacttgtaa
     4501 caataccttt atactaagac ttattttaaa tgtagcactg taataataaa ttgtttatat
     4561 actcataatg tatttgataa attgtaaatc tttatagaag ttgaaatttt taatgatttt
     4621 agaatcaaga tataataata aatacaattt ataaaatcag aaatatataa attaactata
     4681 caaacctaaa taacatagca tttaaattca caatttcagt ataaatagta caaagtatat
     4741 taatttaaat aagattggct tatttgtaga ggagagaata ttttggtgtt caataaaatt
     4801 tatatttaat aaaaccataa gaaaatataa agataaataa acaaactttt attacttaat
     4861 agattcttat ggttttatac tgtactgaaa aacaataaac actacagctt atttataata
     4921 ttacgctttt ttaacaacag aagactttag cttcatagct ccaaaaccat ctatcttaca
     4981 ttctatatca tgtccatctg atgagtcatg gattaaacgg atatttttca cttttgttcc
     5041 aatctttata gatgatgaac ttccttttac tttaaggtct ctaattactg taacagaatc
     5101 tccatcattt aatacatttc catttacatc tttgataata tttgaatctt cttcagctcc
     5161 caatcctaat gcccactcat gagagcattc tggacaaact aaaagagttc catcttcata
     5221 agtatattct gaattacatt tcgggcaatt tggtaaattt tccatcttta tatgtcctcc
     5281 atttgttatt tttaaatttc ttattatata aaatttcttt tgagccttta tgatatcata
     5341 ttatacttat atttacaaac tactaattta cttaatgttt aaattctatt cgtattatta
     5401 ttaaacttga tttagctgta atctctttct tatatttatt atagttgata ttattacaat
     5461 tttataactc tatctgcctg ctccgataac tctaaatcat gagttacaaa tacgatagtt
     5521 ttaccattct tatttagatt tttaagtata tcaaatacta tgtctctatt ttttttatct
     5581 aaattacctg taggttcatc tgcaaatatt acttcacatt cttttaatat tactcttgct
     5641 aatgctaccc tttgttgttc tcctccactc aattcgtata tctttttttt attgtatttt
     5701 ctaagaccta cagactcaag tgcgtaattt attttttcat tatggttgat atttttttga
     5761 tactttaaag caattttcaa gttattttca acattttcat tctcaattaa agcataattt
     5821 tgaaatagat agccataaaa atccctttgt aaaattctta tctgtttact atttggattt
     5881 tttatattat ttattataat atcaccagaa ttaggttttt ctaataatcc cattatatta
     5941 agtaaagttg tcttacctga accactattt cctgttatcg ctacaaactc gcccttagaa
     6001 atttctaggt taaatttgtc tattatagat ttatctttaa attttttaga tatatttatt
     6061 aatgaaatca tctttttaat gttctccttt tataatttta ttaaatgaac tatttgagat
     6121 aatcttgtct aatacaatag atacaattac ttctataact aatatcagaa gtccaaataa
     6181 gataatatta ttacttaaat ctactcttgt tgatataatg cctattggaa taatgtttgt
     6241 taatattaat gagactatta acaacatact tctagctgta gttgaataac caaatatttt
     6301 tttaatatat aacttatatt tatttctttc atagtagcta gctactatat tgtaggtaat
     6361 cattaagttt gatattgcta ttattattat agtaaaaatt tcactattca aatatttttc
     6421 tagtttattt atttctaaac catactcatt ataaacagca tgtaaacttt ggatatgcgc
     6481 ttctacacct tgagcttcaa taatgttact tatatctgca agggcatcta atttcttaga
     6541 attaaaatat acacatctag atatataaga aagataaaaa gaatcatcaa tattatctat
     6601 gtcaattatt gctattgggt catcaatgag attcctattg tcatccataa caagggagtt
     6661 ataagtaaaa tagctttgat tattatctac atatattata ttaacattta aatctgactt
     6721 ctttgtttta tttaactctc tatttaactc tttattgtac atattttcta cttctatttt
     6781 ttcaaaataa aataattctc taaactcttt tttaatctca ttttcatgta cttgtaactt
     6841 tttaggaact aataaattta tagtcttatc gtcataatcg attagattaa atatttcttt
     6901 gccatttgag taaatagggt taactttaag atagttttta tttattttta tatttttacc
     6961 atattgactt acttctgggt ttttaccctt tgaatttatt tcatacatgt aacttccatc
     7021 ttcaagtttt tcaaaattag ttgaatctat taagaaagca tctttttctt ctaccaaatt
     7081 tttatagaaa cctttaatct tggcattttt aattacttct tcctttccta aagattgttc
     7141 gcctgtatct ttaagagtaa gattataaac attttttgct ttatcccact cagatagatt
     7201 tcctaactga gtttgtagca tattataatt taaaatacag ttatttatgg ataatataag
     7261 aaatgataca aatacaattt tcaatgtgaa atgcattata tttacaaaac cataagattt
     7321 ttttccattt agagatagca catatttaga acttctacta ttaaaaccaa ctattaatat
     7381 agatatcaaa atatttatca aaatacatat aatcgaaaac atagcaaagt ataagcatgc
     7441 tctaacacct atatttaatt ttaaaatata gattatatat attaataatg ctgtgacaga
     7501 tgataaaatc ataattctaa gtatattttt tataacccta gcaattatat ctagcttaga
     7561 gtatccattt aatcttaaaa tagaagcctc tctactcaca ctaattgaat aatgtattat
     7621 tgtagccaag aaacaaagga taattagtat taaatctcta attattgaag gatttaagta
     7681 taaatttgag ttaacatatc tatcatgtaa tcttgctaca aaaatacttc tgtctacatt
     7741 tagttctctt aatattttat ttattgtatc ttcattttga gttgaaatat ataagattcc
     7801 tgattctcca acttcactta ttttaccaaa atccctaatt aaaattgata tgtctttact
     7861 catagttgag aatttaccta cttgattact attattacta ttattagtgt ttatattact
     7921 aataaattca tttgaattag tattaggaaa ttttcctgat tttaacttta tattgttatt
     7981 caaacttgta tcagtcgtat atatagataa tttttcatta ttattaaaaa catactttga
     8041 tatagccaca ttattttcat ctgcaatatc tttaatccac ttactataat ttttatttaa
     8101 ctttttataa tctttaaaca ttacagatat acttgttgta tcgttatata aaatattatt
     8161 aatttcatta tctttaacta tatttagacc taataaagat actattaata gttcaattgt
     8221 aaataataca tatattatct ttttcaatta tagctccctc ctaattgttt ttattctaaa
     8281 agcaaaatat attttacttt agttaaagta taatgctttg taccttttct aaacaactac
     8341 tatattgtca cattctaaat ggcaagtgtc tatttcgtca caaagataaa aataacctta
     8401 aaacagttaa ttttttataa tcaactgttt taaggttatt ttttattttt agcaaacaat
     8461 attttaatag tggtacaaaa ttagtataat tcattaatat agattctagt atttttagca
     8521 atcaactaaa ataatatctt atttaaaaca aaatttaatt taagttcaat ataaacttta
     8581 ccttaactag aaaatatttc ttctaactta ggaattaatg tgtggatatc tcgtcaatag
     8641 aaaactaatt catcctccat gttaaatttc tcttatattt ttaatgattt cacgaatctt
     8701 tttggcattt tcagtaatat cctcaatagt tcctttagtt aataaaccac caaatccaca
     8761 tacatcaact ccattttcta accatatatg taggttttca agattaattc ctccacttgc
     8821 taaaactggc atatcaggta ttggtgtctt aaataccttt actagtttag gtccatagaa
     8881 atctgatatt gggaaagctt ttataaaagt tgctcctaaa cttagtgcat ctactgcctc
     8941 agtcaatgat gtacatcctg gagcataagg aatctgatat ctattgcaaa tcttcgctac
     9001 accttcattg taatttggtg caataataaa ttgagctcca tgtaatatag catgacgagc
     9061 tgtttcacta tccaaaactg ttcctgctcc cacacaaagt atttcaccat actttttatt
     9121 aagcccttga attatttctc cagcattatt tagggtataa ctcatttcta taactgttat
     9181 accacctttt atacatcctt cagcaatttc acatgcacgg ttaagatttt cttctcttac
     9241 aattgcaaga gccccacatt ctgacattct tttggttata ttcatctttt tcatattatc
     9301 acctctatac tcatcaaacc actttactta ttcattaatt ttagtcatgt tttataatat
     9361 atatattaat tatataccag tgtaatttcc ctatttatat tatctattct cactactttt
     9421 attaagtatt gtcctataat tttcaactac tcgtttaatt tcttcaagta cttccccagt
     9481 tggttcagtt acaggaagtc gtgcagttcc aacattaatt ccattcaaga caatagtttt
     9541 cttcataaca gatggaattg ttccaagttt tagtatacgt cgaagttctt ctatactact
     9601 ttgagctttt tgagcttctt ccaaatcccc tttcataaag ttttcataga tagaaatacc
     9661 aatctctgtg aggaagtttg ttgttgctgc aacagctcct tgactaccaa cttttagact
     9721 atccagaata agtgaatctg agcctgaaaa cacactaaaa ttctcattct gcgttacttc
     9781 aatataagct ttcatgttgt caagtttacc actactatcc ttaattccaa caatattctt
     9841 tatctttgat aattcacgta ctgactctgg ttcaatatta attccagtct tacctggcat
     9901 attatacatt ataataggta aattaactga attagcaata gttttgtaat gtaagattag
     9961 ttcctgttgt gttggtgtaa caaagtatgg tgtaataata gataatgcac ttgctccaat
    10021 cgcttccatt ctcttggata aatctataac ttcacgagtt gaattaccac ctgttccaac
    10081 aaaaacaggt acacgattat ttgtatgatt aataacaatc tttgcaaatt caactttttc
    10141 atcatctgtt aacacatgac attcaccatt agtacccaaa ataaataatc cataaatccc
    10201 cttttcaatc aaataatcaa ttaatttaca tgttgcttgt gaattaatat tttgcttttc
    10261 atcaaatggt gttatcattg cacatataat ccctttatat ttcataaaat tatattccct
    10321 ctctaataga ctttccaaga cttcctgctg gatgccattt caaatactgc tgtgtattaa
    10381 gacctttagc atattgtaat acaacactta atgattgtaa tactattgtt tcagctaaaa
    10441 ttgaagcacg aggagcttta ttaagacaat ctccttcctg tttaacgcct gcgaacagga
    10501 atatatcaga aatatttttt aaaaatgaac tctcattacc acttacacca attatttttg
    10561 ctccatttac ttttagagtc ttaagagttg cttttaactc ttgagtttca ccactatttg
    10621 atattgcaat aacaacatct ccttcaacta cttgaccact tgacccatgt actgcttctg
    10681 taccatgcaa tatatatgct gatgttccag tagatgaaag caatgatgaa atatatcctg
    10741 atacatgtcc tggtttacca ataccagtca catgtacacg tccgtgattt ttttcagctt
    10801 caagaattaa ttcgcatgct ttatttatag atgtctcatc tattgaggca ataaattctg
    10861 acaattcatt agatatatta tctaaaaatt cagataatgt attttccata agatgtatcc
    10921 tccttgaaat catagtaact atgactatac ttttatataa tttagtttaa ataggtttta
    10981 taaattgtaa aatattatgt aatatcgaac caactacgtt gtaatcaata ttagggaaag
    11041 ttgctccttc tataccaaga gtcccataaa ctggatatag tataactggt aaaaatgcaa
    11101 gtaataaccc aacaacaaat gacccagcaa tagcccctct ccatcctcct gaagtattgc
    11161 caaatattgc agctgtacct cctgagaaga aacatatgtg agcagctgga ataattacta
    11221 caggaaatat actaggaaat gatgccataa tagcaattgc taatagacca gcagcatatg
    11281 ctgatataaa cccaataata actgcatttg gtgcatatgg aaatactgtt ggaacatcta
    11341 gcgcaggacg tgaacctgga atatactttt ctgaaataat tacaaatgct gcagttattt
    11401 cagctaagaa catacgaaca cctgacatca atattgacat acctgccaca aatgtaaatg
    11461 cctctataag cggaaaaacc aaccaatgtg ttgaaccagc aatttcttga gtaaatgctt
    11521 gaccagcttt taatgttgca atataaaata agattaacat aactatggat agacccatta
    11581 agaagtctct gaatattgat aaccacttag gaaattctat agtctctgtt gtatcatctt
    11641 tatactttga aaataaacgc ccaatataac ctgataaacc ataaccaatc atgttaaagt
    11701 gaccaatagc ttgttcatcg ccacctgtta attcacgcat aaatggttga caaaattgag
    11761 gtagtgcagc agacataaac cctaagatag ttccacctat taaaatagtg attgtattat
    11821 cgaatccatg tgctttcata attaaaacta atacacaaga aaagaacaaa ctatgacctg
    11881 ttgtaaagaa aatattctta aactttgtaa tacgtgcaaa tactaaattt aatatgaatc
    11941 caagaattaa tgtacatgaa actgcaaaac catatgtacc ttgtgcaagt gctgtagctg
    12001 cttctggtga agctataaca ccagtaattc caaagccatg ttggaacaat ttattgaaat
    12061 tttgaagtgc tcctgtcata gcagaggcac caataccaaa tatcaaaaag ccgataagtg
    12121 tttttgaaga gcctgtaaat acttcaacag ctgatttctt ttgaagaatc aatcctatac
    12181 atgcaactac gccaagcaaa acagcaggtg tactcagcaa actaataata aactccataa
    12241 atattcctcc ttatcatctt aaatttatcc ctcttttgaa gcaaggaatt tttctagtgc
    12301 tgtctttatt tcattacggt caacaatatt gtgaatccca attatatcaa acttcaaatt
    12361 tttatttttt aattcttcag caacatcaat taatgtttct acagcatctc cattgaatcc
    12421 atttagtgaa tccaatgaac catgctctac ttcaattgga aagttatttt ccttaataat
    12481 ttgttgagtc tttattttta acattaaact tgagccaact cctgctctac atgcgattaa
    12541 aattttatac ataattaaat cctcctttat aattcgtgtg tttttataaa atcaataatt
    12601 tctttagctt ctttagcact atctaaaacc ttaaaaaact catcttcttc caatagttca
    12661 actagctcag acatagcacg taaatggcta ttattgtcta ttgcacttag acaaaataca
    12721 tattttacag ggtcgttttc gttattccca aactcaatag gactatctaa agtagcaatg
    12781 cctattgcaa tctcttttga cccagcttct ggtctagcat gtggaagtgc aacatgtttt
    12841 gtaattacta tgtatggtcc agatgctttt gctgagttaa tcatagcatc tacataccct
    12901 tcagttactt tgttattttc aactaataca gaagctgact gtctaatagc ttcctcccaa
    12961 ttcttagctt ttacctttat ttttactagt gtttcattag taatctcact tagcataggc
    13021 ccctctcctt ccttagatgt aaaattctct atctgtgtaa aataagctaa tagctcactt
    13081 gaaagaatac tttcagaggt tacatttgca tattttttta ttatatccat aacctcatct
    13141 attttaggtt gtcttaaata aatatcacct aattgaatat acacttcacg tgtaatctta
    13201 tatttttctt ttgtggtcat aacagggctt actttaatta ctggtacatc tgtttttaaa
    13261 ccctctgcgt tataattagt agtaaataca atatctacag gttcacttat attttctaat
    13321 ccaactgatt ccgacattgg tataaagtgt aagtcaggaa ataagtttgt aagttctgca
    13381 tgtaaaatag ctgaactacc aacgccattt gaacaaacta ttaatgctat tctttttcta
    13441 aaaccatcaa attctttttt atttgaaaaa agtgttgcaa agtgcattgt aagatatgct
    13501 aactcttctt cctgaatttt ttctccaaat aatccgcaaa actctttcat tgcattactt
    13561 acaattctat aaactaattt atattcttct tttacttttt cacaaatcgg attatagata
    13621 ggtaatttaa ataaaagtct atagtaggca ggtctaaaat gagaatataa ttgtttaaat
    13681 attttttctt ggcttatata gtaaactccg cttaaatatc caaactttgt catcatttta
    13741 tttacaattt ttgaaattac atccttatct tctgtatctt cttcataatt tcctaccgat
    13801 atacctaaaa tccaagcact aatatacatt atattataag gctttatctt atcctcactt
    13861 ccatatactt ctaataattc cttagcaaat ttatactcct tcattgaact cataactgaa
    13921 atattaggaa tatctacatt ttcctgagta actattctag ttgaatacat ccttgctttt
    13981 agaaagataa atatatatat aaattctatt aatctatctt caacaaaagt aatttcatat
    14041 ttttttatta gctttaatat aattttttta gcctcttcaa aactatctaa attatattct
    14101 ttaataaaaa tatcaaatac tcttgaactt ttctcattag acaaagtttc tataatgttt
    14161 ttaataagta ctctcctaat ttccatctca ttgccaacta tgtaatatcc atttatacga
    14221 ttgttcttaa ctttaatgtt cttcttttca agctctggta tcaaatcctt gaaatcaaga
    14281 tttacagtag acctacttac ttttatagaa tttataaaat gattaattga aatatcctcc
    14341 atgttaataa aaagcattaa atacatatat aaaagtcttt ctgtcttact aaaataataa
    14401 gtattcttag aatagttttt ttctaaaatt tctttaattg ctttttttgt ttcttttcta
    14461 acgataatat ctttatcagc ccttaaacat ataagtggta cattttttac tttaagcatg
    14521 tcattgattt tatttattct ataagtaatt tgtctttttg atgaattaga ctcctcttgt
    14581 aatccattag ttgtaatcaa tgtgctattt aataaaatct ggagaattga tacaatttct
    14641 ttgtccacta ccattaaccc ctactttctt attaagatta gtcttcatat tatcattgga
    14701 ttctttcatc acctccacaa tacttatttt atttgagaat tttatcgttt tcaatttcat
    14761 ttaagtataa cttttgtttt agattgagac aaaaattaaa cttatctaaa atagctacta
    14821 tattacactt atagatttta taaataaaaa agggttcctt atgtaaagaa accaaaaaaa
    14881 atttatttaa agaatcaaag cgatactaat tatgcataaa ttaccataaa taaaaggcac
    14941 attaatttaa aataaaatta atgtgcctta tttataattc taatatatta aatttatttt
    15001 ttaacttgta gtttaatatc ctttttcttc aattaattca tataaataaa gtatttaata
    15061 ataaatgttc cttatgactt taatatttta aaccaagaaa gttaaagttt ctctcatata
    15121 ataaattgac acttatctat ttcattcttt taaggataca ataagtcttc ttctaccagt
    15181 aagagtaaat gcctcctcta cttatcacaa actataattt ttatctcatt ggtatatatc
    15241 cacgatactg tgagtatgca tccatagttg ctatatcacc taagaatact gatgcgatat
    15301 tgaattgtgg ttttaaatat gggaactcct cttcttgtgc ccattctggt tttttaataa
    15361 acgactttgt ctcttcaacc acagctttat accattcctc ttccccttca aaccatagtt
    15421 ctgatacacg gtcaaaagca gttgctccat aattaatcat tattttacta ctgacaaaac
    15481 gattaacata gcaacagttt gtaaagtatg gcactacctc atcatagaac catttttctc
    15541 cttcttcttt agagatacca tctggatact taatcataaa ttgccaacga tagtttggtc
    15601 catcttgtac agtacgtcct tttcctctaa agtcttcttc ccagtttatt ggaacaaaag
    15661 caaatataaa tggtggacat ccattatctc cacctactgc acgtcctgca tctccacttt
    15721 ctgcattttc atgaaccctt ttattttcta catctggtat acacccttgc caacgtagaa
    15781 catccatagg catatattct gtcataattc tatttgccat ctcaggcata tgttcatcta
    15841 caagccaata atgttctgtt agttgcatct tacgtgcacc aaaacgctca ccttcatttg
    15901 gtgtaggata tgcttgataa aaggcatatt tagtacaata tggtccaaaa gtgctaatac
    15961 tatctggaat atggtgacga tataaccagt ccattaactt aggtctatat tcttccttgg
    16021 caagtcctac atatattaaa cttctcatta ttttaaattc aaaacccata gccattctcc
    16081 tataatcaaa gtatattcac atgctttcaa tttccctttt tcttatcttt actcaaaata
    16141 tatattgtaa acaaatctac acctgcaccc acgtaccata ctcctactgc catagctaca
    16201 gcaatttgaa tacaaatatc ttgtaaatta ataatatttt cacctgtcat aatagttaga
    16261 cctatagccc aaccacaaag ccatgatggt aggaaaatta ttttttcaaa taaggatgca
    16321 attacaactg caaaaaaacc taatatacta agtgttaaaa ataattctag gttttgattg
    16381 aaattcatat atcccataat taaaatggct aacactgccc ataaatctcc acaccaaaaa
    16441 ccaaacatta tttttaatcc atctttttgt ttattaccat tagttacata taatcctgca
    16501 cagattagtg ctacagctcc agtttttatt cctatataag gtgctaatac tgcccataaa
    16561 ggaggtagta aagcaatccc catagacagt gttaatattt cttttttctt tctatccatt
    16621 tcctatattg taattagtag cttccctagc ttgccttatc tccaatagct taattgctat
    16681 ttgatttaca atcatagata ctgcaaaata acttaagtat aatggtataa atataacaat
    16741 aaatgctgga gttaatccaa tcttgtaata tgtaagtacc aaaaaaataa ctgctaaaat
    16801 aatttcaatt tgtttaaaat ttggcttttc attcatacaa taagcctcct ataacatcta
    16861 acatccctta aaaaagagtc ttagtatttt aattattatc ctaatgaaac tccagcttgc
    16921 ttttctttag ttaatggctc tataaaatta taagatgttt ttctttcttt aaattcttgt
    16981 gttttacgaa cttctgcata atgaccttcc attttcttaa tatcatcacc atgtataaac
    17041 ttacctggta aagtatcatg agcatgacct aattgctctt ctggaaaact aaatatagtt
    17101 tttccactta tagtatctaa ctctccaact ataccacata gagcacaaat tgccttttta
    17161 gtacctgact caaggtagaa taatctattg tggcaatgtg gacatacacc ttcttctcct
    17221 tgatatgaag ctttttcaaa atcttttgct gcttcaacta tatttaaacc aatttgatga
    17281 acttgaacaa gccttgtatc atccattact aattcctttg cccatgggaa ccaagcatta
    17341 tctataactt tccacattgg tatgagagct agcatagcat gttcacattg aactcttgta
    17401 ccccagtcag aacctcctat tcccataaat gatattactt tatcattaag cattcttgag
    17461 tctggaattt ttcctcctat agcttctgca acttttgttc ctataatgtt atttcctcta
    17521 tctgctctgg gtccaaaacg gtccattata gtatggaata atcctgatgc cccttcttca
    17581 aaaatagggt ctgaaactac tataccatct gcatctttca ttttgtcaag caaccattca
    17641 aaatcatctt ttaatacaca catactacct ttcccggata ataaagtttt aacgcacgca
    17701 caacatccag tacaatgttt aatgttaata gatgacattt gaataaattc tacttcagcc
    17761 cctgcttctt tggcaccttt aagtgcaact ttacacattg tgtcattatt tccatttttt
    17821 gttccaaaag aaatacctag tattttcatt ttcaactctc cctctttagt atttatttaa
    17881 tcttctttca tttttaatat atagaatcca tcatctaaag catctatgat gatatagcct
    17941 ctatcatcaa cgataagatc ttctgttact gccaagcgtg gtcctgggaa tcctgggaaa
    18001 taagattctt ctggtgtttt atttggattt ggtggtataa aatatgctag ctctttgata
    18061 taatatgggt ctgatacatc ataaaccctt agccctgcat ggaaataaca gcaatatact
    18121 ctatctcctc tttgctctaa ccatggctta ttatccattg gttcatgaag attatgtgga
    18181 ccaaatggcc ctgcttttcc taatcctgca acattaaagt taggataagg gaaatctttt
    18241 ggaacttcag gatatgggaa ttgagcaatt aatgttggtt ttgttgggtc actaacatca
    18301 accatatgta tattattcat agcttgaaca tctgtaatgt tatctggttt aaagaactgg
    18361 aatctttctc cctcattttg aacaacgact aaatctcttc ctggcaatgg taatgctgta
    18421 tgagttcttg cacctgcaag tctactagaa aatgcaggca taaatggcaa ttcacctaag
    18481 catcttggtc ttgttaaatc ttcaacatct aatacaacta aaccagctcc tccataacca
    18541 caatatgctt ttccgtctct tacaaatgga ggtccatgaa gccatccttt atccataaat
    18601 tctgggcaat gaggtgctcc tgcatcaaaa gttctatttg gatatccatc tgcatattgg
    18661 tctggtctcc accatttacc tatttccact ggattattag gatttattat atctatgacc
    18721 ctataaatca gaccttcaaa gccaacacaa tcacttgata aatgtacata tcttccacca
    18781 ttgtacatga atctatgaac acccattaca tgctttaagc cacaatccca atatcctaaa
    18841 aacttaggat ttaaagggtc ttcttttaaa ctgtatattc taattcctgc ttcacactta
    18901 atatttgcta atttagcttg gtcaacaagt gctcctggtc cacttccaca actcattgct
    18961 actatcatta aatcatctgc tatttgaatt tttggagttg ttgttgtagg atactcttta
    19021 gggtctaaca tttgaaaatg ttttataaat tgtggattat aagggtctgt aatatcgcta
    19081 atcattactc catttttttt atttcctcca aaacagcatc catataaata gtatttttca
    19141 tctcttttgt acagagccat ttgaaacatt ccacaagttc catctaagtt attaaaggaa
    19201 caaacttcaa gatttttaat atatccgtta tttccgttgc cttttgcata aaatttatct
    19261 tccatttttt ctcccttctt atttaaagta ttatcaattg atatactttc attttatgag
    19321 acaaacttac ttaaatccaa tattgttttc attggaatat ataagttatt cttattaata
    19381 aatttataaa atctaatgta aatatatact taaaacatat atttttatac aaatattttc
    19441 taatattctt taaaagtaaa ttttcttata ctataataag ctttaattat agataaataa
    19501 ggtttacaaa caatcaagtt taaatagggg tgattatttg aatactaaac aattagaata
    19561 ttttatatct gtagcagaaa atctaagttt taccaaaaca gcagaaaaat tttatatttc
    19621 tcaaactgct gttacacagc aaataaaagc tttagaagaa caaataaatg taactctatt
    19681 tacaagaagt aaacgtcatg ttgaactaac accagctgga aaagtttttt tatctgaggc
    19741 acgtactata ataaaaaata tcaatgatgc tattgcaaaa acacaacaat ttgcacatgg
    19801 tttttttgga actttgagca ttggaacctt aataggatat gaaaaaaaca aacttcaaca
    19861 atacttaaaa gaattttcta atacataccc taatatatct atggatattt gtactaatga
    19921 aataaccgaa cttttaaact tagtaaaaaa taattctatg gacctcgctt ttgttattaa
    19981 tccagaaaac caaccattaa aagattttga atataaaact gtagaaagat attctttggt
    20041 agctctttta cctcctggtc atccacttta caatgaggat tctatcgatt taattgaatt
    20101 acaacatgat aaatttattt ttgtaaaaga aacaggggat gagtatggac aaaagtcaat
    20161 gatacaaaat agatatcgtg aagcggggtt tgtacctaat gtggtacaac gttcaaataa
    20221 tcttaatact attgaatcat tggtatcttc taacatggga atatccattt taccttcatt
    20281 ttgtgttaca gatacaatga tagaacgtga tattgcaata gtacctataa aagaagtaga
    20341 aaatagaatt gaagttgtgg ttgtatggaa taaaaaaaat acaaatccag cattagaaaa
    20401 gttcatttct ataatataaa attaatcaat attaactata aaaatagcat taaccatttt
    20461 tatatggtta atgctatttt ctactatttt attatttaac ttttaattta atatttataa
    20521 tcgttaaaaa taactctgtt taacaaatat aagcaagtca aaagtgtgtc taaaaaagat
    20581 aaaaatttta ttatatacaa atgtattatc tcaatatatc tattttttca ttgttcatca
    20641 gtctaagtac atgacctgtg cttactaaaa aattatcccc ataagttgta tgagctaaca
    20701 ccgaactagc aaccccaaac tcaactatat cttcactctt catattttcc aaatatgaat
    20761 atataattcc tgccacatat ccatccccag caccaactct gtcatatatt tctaacttat
    20821 actccctact ttcaaaataa ccatcatcat ttgatatata tccctttata aatctattat
    20881 tcatatcatc aaatcttctc atagttccag ctacaatatc tatatcatac tcttttttaa
    20941 tcaattctga actagatttt atatttagac tatctatatt aagtatctta tttatatctc
    21001 tataactagc aaacagccca tgacaatatg gtagtatttt cttatactca tttactaaat
    21061 catcataagt cctttctgga tttaatgatt gtctaaaatt aaaatcaaag aatactttta
    21121 tccccttttc ataagatttt ctagctagtt ctaaagcaat ctctttaact gaatctgtaa
    21181 gttgcatagc aataccacaa atatggacta tatccatttc ttctaaacat ttatcaatat
    21241 cataatcttg taatttactc tcacaaaatg aactatttaa cctattcaaa taagtcactt
    21301 cagaaggtct ttctccatac ccattttcaa gaaaatacac tcctatatga ttccctccat
    21361 atgtgataaa gtcatctttt actccaagct ttcttatatt tgcacttgat gctttaccta
    21421 cattattatt aggcaacttt gtcaacatat aggtattgtg tccaaagttt ttaagtccag
    21481 ataatatatt taatcccgtg cctgtaatta tataatttag ttcattggtt tgtgttaaga
    21541 acttgtagtc aggtactgaa agtctcatca ttatttcacc aaaagctaat atattcataa
    21601 atctatccca ataattcttt cattatttta taaagtactc ctatatcttc cactttcgta
    21661 tcacctgttt ctttatcaat tattgatgta taaacatgag gtataacttt ttctacacca
    21721 gcatcaagtg caatttgaac tatctctttg aagttatcta agtctatacc ccctgttggt
    21781 tctaaataaa aattatgctt tgcacaagct tttgcaactt ctatatattc atcctttgtt
    21841 ttaagccctc ccattggaaa aaacttaatt gagcttcctc ccatatcttt catcatagct
    21901 attgctgttt ctataggaac tataccatct ttttcttttg aacttaatgg acctgtggat
    21961 atttttacaa atcctggttt accagttgga gaaactaatc catttattat actatcattt
    22021 tgaccaagca atgctctaga cgtagccaca cctgtaaaca cttgatttat atgttgtggc
    22081 tgaagttctt tagaaatctg agataccata tttgactgat ttgggtctcc agctccaagc
    22141 cccacagata ttgcattatc tatttccttt gagtattttt tcatatcttc aatagctgct
    22201 tctacagtga tataattctt tgatagtact cctactagta catgtccatc acaggcatca
    22261 tatacttctt tagcattttt tatgcttcct gcaagaacat ttaaacaaac tctattttta
    22321 taatattgcg gtatacaatt catatttatc ccctccattg gtaaaattca atttattaaa
    22381 tcattataat gtcacttact ctacactcta actttctact atatttttta tcctattata
    22441 aatagtatct aaatcacttc cagttacact tcttatatca atctcaatct tgccttcatt
    22501 agccttatag tctctagtgt atatagctat ctctccactt ctaagttcat ttataatttg
    22561 ttgtgttgac ttatttatta tatcttcatt aaagtcaatt tctccacgaa gtatttctct
    22621 acctgctgaa tctctagtta tactagcact cactccattt atagtattta tcttgtctat
    22681 aaatggattt agcttgtcct ccatttcttt taaagttact ttatcattac ttatatatct
    22741 ctcaattgca catgttagac ctacaatatt ttcttttcct attttcatag ctcttcctat
    22801 accctttgat tgaagcttta cattatctat gtattttttc ttacctatta ctaaccccga
    22861 gctaggacct tctatagcct tagcaccact gtatatcact aggtctgctc ccaattcata
    22921 atatacattt aaatcttctt ctgctgctgc atctactatc aaaggtaaat tatattcttt
    22981 agcaacttgt actgcatcta atacacttag catactcttt tgaacacaat gatgagattt
    23041 aatatacata attgctgctg tattttcatt tatctctctt attatatgtt ccttgttaca
    23101 catattagca tagccggcct caacaacttc tcctcctcca agtcttatca ttacttctac
    23161 tggaactcca taatcaacat tatgcccctt tggaattatt atttcccttt taacttgttt
    23221 cttaggatta tttacattgt aaactagact catatcatct tttgctatca ttgctcccac
    23281 actctgtgca atcccagcag atgcactaga aactattagt gcactttcac accctaataa
    23341 atttgctata tattcacctg ttttatttac aagttcttct attataaaga aatttttaca
    23401 cccttcacct attgcttcaa taacttcctt atctactgtt gatactccta gtatagtcat
    23461 tttgcctgaa gcatttataa cacgtcttac agagtatttt tcaaatatac tactcataca
    23521 atagtttctc ccttctattc attctcttct atagacttgc ctatatttaa atattctcca
    23581 ttgactacta ctgctcttgg ctttatagac gtacttgtga ttactgactt attcaaagaa
    23641 tcttgaagtt ctttttcttc attaaccaca tcaaatatag ttaaatcagc atcatatcct
    23701 tcttttatta aacctttatt ttttaaactt attgcatctg ctgcattttt agtaacttta
    23761 tctattatat cttcaagtga atagcccata tatataaact tttccattgt tgtagataga
    23821 ttatacactg gaccatttat tctattttta atatatatat ctgtacttat agtgtctgga
    23881 aaaattcctg catccttaga tttcattgca atatccatac taaaactttc ggttccatga
    23941 cctacatcaa gaattatacc tctttctcta gcttctatga tttccttttt aacctcattg
    24001 cctctaagta ttccatttgg ctttccatta tatatatggg ttaatatatc tcctttttcc
    24061 atataatcaa atatatcctc tatcgttgga ggagaactcc caaagtgaac catcataggt
    24121 agattaagtt cattttttat tcttttagct acttttaaag gttcgacatc atttgaaatt
    24181 acaacacttt tactcattct agctttgatt ccaacaacaa aatctttgta ttttctaact
    24241 gcatttttaa gttcatattc atcaatattc atcatatttg aaagttcatc ttgagatgtt
    24301 attccctgct tagcaatatt tattaaagca tatacattgg tcttatactt tttagtatct
    24361 tcataaaatt cacctatatc taaagctcct gttgttcctg catctactac agtagtaact
    24421 ccacttttta ttccaacctc atctggataa tccttataaa ggtctagtct ttcgtagcag
    24481 tgtgtatgta tatctatcca acccgcacta ataaatttct ctccatctaa gtttataatt
    24541 tgttttgcct gatacttaga atcatctata tgatttttta cttctattat tttatcgtct
    24601 aatatagcta tatcaattat acttttatct actgtttttc cacattttat taatatgtct
    24661 atcttcactt tactctccct ctaaaataat cttaaattta ctccaaggtt caataaagtc
    24721 taaaagtatt atttcgtctt cctttattct acccacctta ttttttcttt catctgtaca
    24781 atcttgaagt atcaactgta attccccttt atactttcca aagtcatcat taccaatcac
    24841 tacatctcct cttttaaaga tgttcttatt atcatgttta gggaaatttt ctttagcata
    24901 tttttttctt acttctgtag atcttgctac ctgattagtt atatctcctc ttctaaagtg
    24961 ttgctcattt accattatta tcttttctac ttcagaagtt ttttcttcag ctactacatt
    25021 aaatacaact tggtattcat ttacttcaga cattcttttt aattcatctt cacttgcata
    25081 tgcatttcct acaattacat catcaatcaa tcctgttgcg aataagtgct tagttgctgt
    25141 agcaatatct aagtttctat gcatttcaag cgtacacagt ccatcattta tattccaagg
    25201 tccgattgtt gcgtattttg aattgacaaa agcagcagtt cttattccat actttttaaa
    25261 tctatttaaa catcttacaa aaaaatcata tggcaagcct gtaccccttt gaggataaaa
    25321 attgtgacaa ccatatatat tatttacatt tggcttgtaa gtaattatat tatccaagta
    25381 tgctacatca ttacttatat ttagttccac ttttaaatca tatggattga aagaaatcat
    25441 agcttcttta cttccatcat atccatagtc aagccttatt ccactagcat ttaactcact
    25501 aaagaatgtt aaatcatcat aagatatttg taatatatca aatatgtttg gagctatatc
    25561 aaggattact tcaaatccta attctcttgc ataggttata atctctttaa aatgtttttt
    25621 aacttcttcc ttaggtcttg taattgaaag catgcacata aatattcttt taaatccgta
    25681 ttttgaagcc atttttatat atgccttatc atcttccatg ttactatgct ctggatatac
    25741 tgatattcct aatcttcttt ccatctttct cctcctcaaa ttacattatt taaaatatat
    25801 aaaattaaag gcaaaggtca ttcctcctac cttcaccctt aataacttat aagctttttc
    25861 tatattttat atagtacaaa acctctatat ctatgtattt ttataaattt tcactcattt
    25921 cttcttgttc tctttgtaat tgttgttttt caaaaacttt gaagaatgga taataaacag
    25981 caaatgatat cacaaagttg attaatacta agatacctgc tagtatactc cagttagtac
    26041 tcattactgc tgctattggt gctggcattg caaatggtaa tcttgctacc atcataggta
    26101 taacccctgt aatagtaaga acatatgata gaattgtcat tattataggt ccaattataa
    26161 atggtatccc tagtattgga ttcataacta ttggtgctcc aaatattata ggttcattta
    26221 tgttgaataa tcctggtaaa aatcctaatc tacctaaact ttttagatat tgtgacttag
    26281 aaaacataaa cattacaact aatgcaagag tagcccctgc tccccctatc catacatacc
    26341 actgtaaaaa ttgttctgta aatatgtttg gcattgcatg agctgatact ccttctgtga
    26401 atgcagttat attttctgct atagacatgt cccatatagg tcttattact ggccccatta
    26461 tagctggacc atgtattcca agtacccaga ataaagttat taggaatact gtcagtaatc
    26521 caccacctaa actatttcct gataagaatc cttttaaagg tgataacata gcacttagtg
    26581 caacacttat atcaaatcct agaatatgtc ttattaccca gaataacatt aaaattactg
    26641 ctgtcggtaa taatgcagta aatgaatttg aaacctctac tggaactcct gctggcatct
    26701 taattgtaat attcttttcc ttcataaaac gatatatttc aactgtaatt aatgatgtta
    26761 cgatagctcc aaataatgat ggtgaattaa gttttgccat atccatccat ctaccagctt
    26821 ctataactcc acctactggt tcaactactt gagttggaac tattgtagaa actaaaaatg
    26881 ccataactgc aagcatacca acacctgttg tatctaaatc gtagctttta gcaagtgatg
    26941 atgctatccc aaaagtagca tatagagata aaaatcctac agtatatcta aatggtatat
    27001 ctaatattgc tttaaatgga gctataaaat ccatataagc atcaataggt atgtttaata
    27061 atattgtgaa aaatgacccc actattgtta gtggtaatgt tgctattata cctgctctta
    27121 cagctctcat atgtctctga ttacttatct tcgctgctac aggcataatc ttgcgctcta
    27181 aaaaacttgc gaatttttcc atagttatcc ccctgtatta ttgatattat cctttattta
    27241 taatgcaata acgatttcat aacataaact aatttttatg taattgataa tatcacttat
    27301 ttattaaaaa tattataaca ttataatgtt tagttgtaaa cattataatg ttataatatt
    27361 ttttgttttt acaactaaac aaaaatcctg agcatattat catttcaata aactcaggat
    27421 tcttattata tttcgtattt aattacatag ttttgtactt ctgtattata tcttgcaaat
    27481 gatagctcaa ctatattatc attctcatca taggtctttc tttttcttcc taataatatg
    27541 tctttagcta gatttagagc ctttgatacc tctagttctg attcttctat aaaaaattca
    27601 tcttcaaatc tagttatatt tatatttctc ctatataagt acatatataa agaactttca
    27661 ttattaaaac tttcaacagt tagattttca tcaaaaggaa tataatgagt aaaaaatata
    27721 tatggcttac tatctaagta atacattcta gtaatcttgc tacagttttc tccaaatata
    27781 ctaaatactt gtgaatgtgt atcatttatt attttttcaa ttgaaatagt ctctttagat
    27841 aacttatgac ctttagataa aagtatactt gaaaaagact ctgcttttga tagcttatta
    27901 aaaaggctat tacttattac ttttgtccct tttccacttt ttttctctac atacccttct
    27961 gattctaata tctcaatagc ttttctaata gtaattttac tgactccaaa ttcttgctct
    28021 aattctcttt ctgttggaat attttcatca attttatatt cgttatttaa tattttttgc
    28081 tttaatatat ctacaacttg tatatataat ggttgatttt ttaacatgat tcacctctta
    28141 aatta
//
LOCUS       DACTZW010000051        27874 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.051, whole genome shotgun sequence.
ACCESSION   DACTZW010000051 DACTZW010000000
VERSION     DACTZW010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27874)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27874)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27874
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.051"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            33..884
                     /locus_tag="JAM15_11705"
     CDS             33..884
                     /locus_tag="JAM15_11705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase"
                     /protein_id="HAT6798918.1"
                     /translation="MKNIISAKELISKLEKNDNLVVIDCRFDLINRTYGIDSYKKGHI
                     KGSFILDIDKDLSSPTKEHGGKNPLQDPLILKEKLEKMGVDNDTAIVTYDDGDLNGAC
                     RLFFQLKHLGLKNVYVLDGGITSFVKEGGELEEKVNIPSCTGKEIRPNINNDLVVPME
                     YVKSKLYKKDTVIIDCRANERYQGLVEPAYSKAGHIPSAKNYFCKDLIKSDFENGSLK
                     DIEFLKKFFKDLNNYDEVILSCGSGISACVNSLALRELDIPHKIYIGSFSDWISYDDN
                     EIKTGQE"
     gene            complement(1017..2630)
                     /gene="ggt"
                     /locus_tag="JAM15_11710"
     CDS             complement(1017..2630)
                     /gene="ggt"
                     /locus_tag="JAM15_11710"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HAT6798919.1"
                     /translation="MKFNAYQHKYSSIRNVVYAKNGAVATSTPLASQAGLEILKKGGN
                     AVDAAVATAATLAVVEPTSNGIGGDAYALVWIEEEKRLYGLNSSGFAPENMELKNYNN
                     MKEMPKYGFGAVTVPGIPAAWSELNKKYGKLSLMECLSPAINYAREGYVVSPNVAKVW
                     KKSYELYEKELIGEEFKPWFDTFSKDGKAPEAGDIFICEEQASTLEEMANTQAESFYR
                     GRLADKIDEYSKKFNGAIRKSDLECFYPTWVEPISTEYKGYKIFEIPPNGHGITVLMA
                     LNILKELELEGNIENVEDIHKIIESLKLAFADSKTYVTDIEHMKVKIQELLSQEYAKK
                     RSLLIDNKEALYPTAGEPYCGGTVYLCTADKDGNMVSYIQSNYINFGSGIVIPRTGIA
                     LHSRGNNFNLDPKHHNVVKPFKKPYHTIIPGFLGKEDKAIGPFGVMGAFMQPQGHIQV
                     LTNMIDFGLNPQEALDAPRWQWIKGKEIEVEPEMPKHIIDSLIEKGHEIKVIHDTVDM
                     GRGQIIFKTEQESYICGTESRCDGHIAVY"
     gene            complement(2845..4782)
                     /locus_tag="JAM15_11715"
     CDS             complement(2845..4782)
                     /locus_tag="JAM15_11715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6798920.1"
                     /translation="MTLFRIAMQNVKNSFFNYLMYFISIVFSVFVFFSFKSIEYNEAL
                     SSLGEKTRMSINTSSIVIVVFVFLFIYYSNSFFFNRRRREVGTYSLLGMRKNQIGKIF
                     LYETFLMGIVAILIGIFLGLLFSKLMTMMLVKLMNEMIVVNMNLSIKALVKTLAVFLI
                     IFIVIGIRNTIVIRNKRIIELFNKYPEKYKFKKFIKLKCVLGVLLIAISYLMSISYFI
                     AENIMLSVFILVTIIPGTFLFFSSTMYMIIDAVKKRKSFYYKGQNLIAFSELGFKLKS
                     NSSVLAVIAILIATSVTMLGFTISLYYDIDRNISENYKYSYTINLGNSYVNNEIDKLL
                     YKYKKDNKIIFDKTIELIDKDINIEMYYKNGNSYIEDRTSVDIIRESDFKKLRQYQNN
                     NYEELTSKESVYYVSDSYKKIFFKDFEIEKINLHIKDTNEYDINLFKVQKSILEPEIN
                     SQATFDLIVVKDDVFNQLKLHGNFRLIRLIDIKNEKKELDLTLKLKNIVSENMKFTYP
                     FNFTSSIESYNNLIKLSGLMLFIGIFLSVVFLLCTGSIILFKQLSNIYDDKERYIMLI
                     KLGANNKDIEKIISKQLKVIFLMPLVVGTVHNLFAMSIAQKFIPRSLLVPIIITLVIY
                     FIGYFIYYFLTLKYALNMIKE"
     gene            complement(4769..5536)
                     /locus_tag="JAM15_11720"
     CDS             complement(4769..5536)
                     /locus_tag="JAM15_11720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6798921.1"
                     /translation="MEEILSVENIKKEYGRKGSKHEALRGITFKVYKGEFVGIMGSSG
                     AGKSTLLNIISTIDLPSSGDIYINGKNTIKMKQNELADFRRDNLGFVFQDSNLLDTLT
                     IKENIMLPLSLKNERVSVIENRIKEISKELNIESILDKYPGEVSGGQKQRGAVCRAIA
                     TKPSLVLADEPTGALDSKSARDLLNCLLKLNKDSNKTILMVTHDAISASFCNRILFIK
                     DGIIFTEIVKGESNREFYNKIVNTVSLIGGVNKNDFI"
     gene            5824..6498
                     /locus_tag="JAM15_11725"
     CDS             5824..6498
                     /locus_tag="JAM15_11725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6798922.1"
                     /translation="MFKIMVVEDDVSLKNIIAKCLTKWGHDVHQIENLENIIEEFKNY
                     NPELVLLDINLPFYDGFHWCNEIRKISKVPIIFISSRNSNMDVIMGVNLGADDYIQKP
                     FSVDVLVAKVNALLRRTYNFVDNNSNQIIHNGVTLDLSTATINYEDNTIELTKNEIKI
                     LHELMKYKGQIVSRNKLMKKLWDNDWFVDDNTLTVNVNRIRSKLNEIGLEDFIETKRG
                     LGYIIS"
     gene            6522..7526
                     /locus_tag="JAM15_11730"
     CDS             6522..7526
                     /locus_tag="JAM15_11730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAT6798923.1"
                     /translation="MSFKDFLKDKLGFLVYNFTFLIFTVSVIIFSPVDVFLTDTILYI
                     LVVNVVFLFLYLFISYIKKNKFLDKIKNDTFKINMNDIELARCKNEEKIYLNIIKNHQ
                     YQCNNIINNNIEKFEENKEILNMWVHDVKIPIAIIKLILEQNENLIDEKILDDIDSEI
                     FRIENSVEKILYLSRLEDFHKDFLIQEVNIEKIIRNIIKKYSKYFISKKIILDLNNLN
                     FKVLSDEKWLYFIFEQLLSNSLKYSSLGDNISIYCKRTKNYLQLRVEDTGCGIKKEDL
                     NRIFNKGFTGNNGRNNSKSTGLGLYLVKELCDKLGHKIDVDSEYNQYTKFTITFKCDL
                     "
     gene            7638..8867
                     /locus_tag="JAM15_11735"
     CDS             7638..8867
                     /locus_tag="JAM15_11735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HAT6798924.1"
                     /translation="MSFLKKFKNKRFRNNSFKSNNFRNSSFGSSGFKSKNKGFKNNPF
                     KNKRFKIYAGIAVIILLILGVLAYVDSKNTELQANENFIETYTIPENEKIFINGMVVP
                     KQTKDFNISGDYELSDVNVTNGQKVNQGDLLFTAKNPTIIAEIDSLKSQLSQYKKQKI
                     SLSDIAENKDAIASINAQITALNSQIASLDKKAYDRVTAPFDGTVYLNDQTGNPDQPV
                     SFMTIQGLEFYMKGQASEQDLPKMKIDQMVNILVFSTDQKLTGRISFISDKPSTPNTE
                     MGAQQNTLSYYDINIAFDNQEGLVNGFHLQASLEVANSSFKIPASCVLKDNKHSYVFK
                     DLDGILKKQIVDVASQNDDFAVVRGGLEQGDIIIKHPTKEMKEGDPVQGDGVTAGSNN
                     GDTTPNKKVEEVTMDVN"
     gene            8875..9549
                     /locus_tag="JAM15_11740"
     CDS             8875..9549
                     /locus_tag="JAM15_11740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6798925.1"
                     /translation="MLIKLENIQKYYKVGKDELHVLKSLNLEIESGEFVMIMGKSGSG
                     KTTLLNILGFLDVFDEGRYIFDGTDVTNLSENERSVFRNINIGFVFQQFNLIETLNVY
                     QNVELPLIYNKALKKSNREEIVKDKLSSVGLLDKLKQKPLQLSGGQQQRVAIARCLAN
                     DPQIIFADEPTGALDSETSREIMELLTRLNKQGKTIIMVTHDQDLTKYATKVIRLKDG
                     VFTSEV"
     gene            9552..10784
                     /locus_tag="JAM15_11745"
     CDS             9552..10784
                     /locus_tag="JAM15_11745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6798926.1"
                     /translation="MSLLKNSLANLKGHKLRVFVALLWIIIGITSVILVSSIGNGFQK
                     EIKKSVNNVNPNKTTISFESADNTGLTDDMSIFLKPFNAKDLEELSFVEGVERIAPSR
                     DGFNLDSVYSSQASFDKKTTYVDVGPVKKDSKINLICGRDFSLDDEKRKVILLTLQST
                     SEIFENPEDALGHGININGTIFEIIGVLDDSQQNQAGGFFGGYQDMQFTTSLVPKKAF
                     DTLMSQNSYSNEIYQLDLVSSKGYNVNEVANNVIAKLYEMHPGINGSYTTPDPTEQTA
                     YLESINSNVNKYVSIITVVAMFVGGIGVMNIMYVSVMERQREIGIRRAIGAKPRSILF
                     QFLVEAVFITVCGGILGTIVGFAATNYVSKYIGFEAIPSLNSLFYAIVATILTGVVFG
                     LIPAFKASKLDPIKAIYK"
     gene            complement(11070..12335)
                     /locus_tag="JAM15_11750"
     CDS             complement(11070..12335)
                     /locus_tag="JAM15_11750"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HAT6798927.1"
                     /translation="MILIKNGRVIDPKSQRDENIDLIIKENKIYKIGKFDESDEYEKI
                     IDASGNVVAPGLVDVHVHFRDPGFTYKEDIESGAKSAARGGFTTVICMANTNPIVDNE
                     DTFNYVKEKSKNACINVLQAAAITKGFEGKELVDMEALKKAGVPGFTDDGLPLMDSNL
                     IMEAMIKAKELDVPLSFHEEDPSLVGNPGVNAGKVASELGLKGASSVAEDVMIARDCM
                     LALKTGAKVDIQHISSGVSVDMVRFAKYLGANVVAEASPHHFTLTEEDVLEFGTNAKM
                     NPPLRSKWDRDKIIEGLNDGTIEIIATDHAPHSKEEKDREFIKAPSGIIGLETSLALG
                     ITNLVHKNHLSMMQLIEKMSINPAKLYNLNIGFIEEGAVADIVIFNPEEEWTVESFVS
                     KADNSPFKGKSLYGKVNYTICNGEIVYNA"
     gene            complement(12388..13536)
                     /locus_tag="JAM15_11755"
     CDS             complement(12388..13536)
                     /locus_tag="JAM15_11755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HAT6798928.1"
                     /translation="MKSVSVRSCKTYNYEEVKLSIEKNLEDIGGIDKFVKKGSKVLIK
                     PNLLMKKKPEEATTTHPMVVKVVCEKLLELNCDITIADSPGGPYNQNSLKSIYKASGI
                     EEVANELGIKLNYDVSDVKIHSKKAHVLKYMDIIKPIVDSDYIINLCKLKTHIMATFT
                     GGTKNLYGCIAGLKKAEIHYRFPTEELFCENVLLDICDYIKPTLTIMDGIVGMEGDGP
                     SAGTTREIGVLLASQNPYAIDVVACKIISLLPNRVATIRGAIKRGYIQEDFSDIEILG
                     EDIKDLIIKNYKIPNVSKDLRLFSVKLPKFLNEPISKLITPKPVVRFQDCIKCGKCKE
                     ACPASTIEIGTKGAIIDLSKCIRCYCCHELCPKKAIDVKRNFVFKYVK"
     gene            complement(13627..14172)
                     /locus_tag="JAM15_11760"
     CDS             complement(13627..14172)
                     /locus_tag="JAM15_11760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010075074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HAT6798929.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEMVWADE
                     HRIGVAQGVDAEIIEGLRANFTGECTEVGMYLAMSRQADREGYPEVAEAYKRIAFEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKRAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRHFGK"
     gene            complement(14395..15339)
                     /locus_tag="JAM15_11765"
     CDS             complement(14395..15339)
                     /locus_tag="JAM15_11765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HAT6798930.1"
                     /translation="MQKNKKEGALLKKYFGEIGLIFIAIIWGSGFVATQFALDGGLTP
                     LQIITLRFFLAAIIMNLLFFKQIRANMGKKLLKAGGILGIFLFLAFTVQTIGLMYTTP
                     SKNAFITAANVVIVPFIGFILYRRKLDKIGIISSLVALIGIGILSLEADFSINFGDFL
                     TLICSFGFAFHIFFTSEFAKDNNPMALTAIQFTVAFLMSVVVQTFAGQLKMEAELSGY
                     MGTMYLAVFSTTIGFLFQTICQKRVDGTRTAIILSTEAVFGTIFSIIILKELITAKLV
                     IGSILIFVAIITAETKLSFLKSKKVKLKDSEESSLESI"
     gene            15725..16606
                     /locus_tag="JAM15_11770"
     CDS             15725..16606
                     /locus_tag="JAM15_11770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HAT6798931.1"
                     /translation="MVKKRKKKTVTLTILVVIVIGIFSMAWADMSRKKEMKETQERLK
                     AERLEKERIEKEKNEPIIGAKKEAVKEYGYDAKIVWDKLNKYDYSNNGEKIVFLTFDD
                     GPSTTNTPQVLDILKRHGVRGTFFIKGDSLERKGANEILKRTFDEGNAIAHHSYTHDY
                     KKLYPGRSLNLDTFVNELNKTDEAMKKVLGKNFSSNVVRCPGGYMSWKNMEPLGNYLK
                     EKNMASIDWNALNADAEGKKKNAQELFENAKKSSEGKEMVVLLMHDTYGKQETVNALD
                     QIITYFKDNGYQFKILI"
     gene            complement(16667..17875)
                     /locus_tag="JAM15_11775"
     CDS             complement(16667..17875)
                     /locus_tag="JAM15_11775"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HAT6798932.1"
                     /translation="MKSIDEQMRIIMKGVDDLIDEKELREKLIKSEKEGKPMIVKLGL
                     DPSAPDIHLGHTVVLRKMKQLQDLGHQIVIIIGDFTGKIGDPTGKSKARKALTTEQVL
                     ANAKTYEEQIFKVLDKEKTIVRFNSEWLAKLNFEDVIKLAATITVARMLEREDFKKRY
                     EGQMPISVHEFFYPLMQAYDSIALEADIELGGTDQRFNLLMGRSLQREFGMESQIVIM
                     MPLIEGLDGKEKMSKSLGNYIGIDEEAGIMYQKSMEIPDELIIKYYNLVTDVHPDEVN
                     KIESQLKEGSVNPRDIKMNLAREIVTLYHGEESAKEAEERFKSVFQKGQIPEDIQTIQ
                     VKEDGFDLIEVLVSNEIVKSKSEVRRLASQGGVKVNGEKVEDLSTIVKESELVVQIGK
                     KKFVKIELVK"
     misc_binding    complement(17948..18200)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(18352..19341)
                     /locus_tag="JAM15_11780"
     CDS             complement(18352..19341)
                     /locus_tag="JAM15_11780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2232 domain-containing protein"
                     /protein_id="HAT6798933.1"
                     /translation="MIYGGSVLNTTKKLTEAALLSSLFIVVTIIAVSTGFGYAIYLDF
                     IVPVFFCIICLKCDLKYTILSGITSLLIISLVLGNLGTAIWASQSVLLGIMCGYLINK
                     PTMVMDDLVYGSVFGVIVMVFIDIYASTLIGYSFMKEFQGYSKWIYFNGCTNFIYYLM
                     IALFPFGMVFCIYLLSLILGNKLHILDSNSLKKFLIFKNFRSLNQFLCCSKKAFYICV
                     SYLAIFEVLKLLNVKVDSVYLKTIFISITYISVYFIIRDSCMSLQNFIIAKFRKLLYA
                     RILFLIIILLLFFIFDVTVISLIIINAFLNKKINIRLSQSNIVNKQINLLIEK"
     gene            19493..19933
                     /locus_tag="JAM15_11785"
     CDS             19493..19933
                     /locus_tag="JAM15_11785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAT6798934.1"
                     /translation="MFKIKHFNDLSLDEFYEIAKSRYEVFACEQKIFSLNDYDDIDKS
                     SYHIFLKENGLICAYARIIPKEYSSYNDVSIGRVLVLSSHRRKGLAKQMMDCAIDFIK
                     INLHENNITLSAQTYIKNLYLSCGFKEISEVYDEAGIEHIKMRL"
     gene            20260..20487
                     /locus_tag="JAM15_11790"
     CDS             20260..20487
                     /locus_tag="JAM15_11790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HAT6798935.1"
                     /translation="MKNLNDIQVKKTVKVEDILSSGNLRERMLALGLTRGAVIDVVRK
                     GPKNNLTVYKIRGSKIALRQEESSLILVSDI"
     gene            20513..22633
                     /gene="feoB"
                     /locus_tag="JAM15_11795"
     CDS             20513..22633
                     /gene="feoB"
                     /locus_tag="JAM15_11795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HAT6798936.1"
                     /translation="MGLTHNSTKMSSLKDMFDIDNKEDQFVIALAGNPNTGKSTVFNH
                     LTGLRQHTGNWPGKTVATARGNFKYKNTEYALIDLPGTYSLFALSQEEIVARDFICFG
                     NPDAVIVVCDATCLERNLNLVFQVMELTDKVILCINLIDEARKKGITIDKKLLEDSLG
                     IPVILTAARNGSGMDELLDTLNDVSFDKYKLNNKPVRYNENIENVVKSIQPELDNIIP
                     GINSRWLGLRLIDGDESIFESMSNYIDKDSIDAINEVKKKIPDNINKQKIRDEFTKIN
                     YDYAKKLSDECCSNVAKKSTDREEKVDKILTSKIFGLPIMLLLLGTILWITIEGANYP
                     STLLSNLLLGFEPSISGILNSINCPSWLNDMLVLGLYRTLAWVISVMLPPMAIFFPLF
                     TLLEDFGYLPRVAFNLDHLFKKACAHGKQCLTMCMGFGCNAAGVIGCRIIDSPRERLI
                     AILTNNFVPCNGRFPTLIAISTIFFSSVITNSFVSSVATALCITLLIILGVIITLLVS
                     YTLSKTLLKGVPSTFTLELPPYRVPQIGRTLYTSIIDRTIFVLGRAVMVAIPAGVITW
                     IFANIYIGDLSILSHVANFLDPLAKLIGLDGFILLAFILGFPANEIVVPILLMAYLAT
                     GSMIELDSFSALGQVLREHGWTYLTALNVMLFSLLHWPCATTLLTIKKETGSLKWTAL
                     GFLMPTILAFVVCFLTTTVYNLFI"
     gene            complement(22766..23584)
                     /locus_tag="JAM15_11800"
     CDS             complement(22766..23584)
                     /locus_tag="JAM15_11800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAT6798937.1"
                     /translation="MEKQYFTTGEFAKLCGISKQTLIFYDKIGIFSPEYKDKNNYRYY
                     SVYQYDTLDILQSLREIGMSLEEIKEYIQNRTPQLCVKMLKEEEKKIREKIKKLRKIS
                     SKMQNRINITVEGISKMNSEEIYISKKFEEYLVLSSDLSNMSNSDFMMELIDFTNYCK
                     SKNLYQGYELGVIVSNENIKNGDYLSISSFYLKIDKKIKDKKLYVKPEGMYACIKHIG
                     KYEDSYKSYEKLKKYIYENEYKIIGNSYEESILDFFCESNEDNYMTEISIQVSR"
     gene            23792..24076
                     /locus_tag="JAM15_11805"
     CDS             23792..24076
                     /locus_tag="JAM15_11805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798938.1"
                     /translation="MLVRVKIVIGATIRYLIKHKVNYCNKKSLDKLELKYGNIDREKA
                     VKLEIFYQYLIELEYIEMSLLIRRLDTAITSLALVSIITIASYYLIRKNV"
     repeat_region   24244..24736
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=24311..24339
                     /rpt_unit_seq="atttacattccatatagttaatataaaac"
     gene            complement(25397..27490)
                     /locus_tag="JAM15_11810"
     CDS             complement(25397..27490)
                     /locus_tag="JAM15_11810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HAT6798939.1"
                     /translation="MNKHNFEVILNQLQINIYVTNIHTNEIIFMNEKMKEEYNILDPE
                     GKVCWQVLYPEKNSTCSFCKVLELLKNDKKGVLITWYGKCNKLNRVFENYDSLITCQD
                     GTVVHMHQSIDIANSTSLNKPIKINEFHEISNNKEEKGVFNFSRDNFDYNSTLLYDAL
                     IRGTDEYIYICNIKTGVFRYSPSQVELFDLPGEIVENPLIYWKKIVHPEDWNRFYKSN
                     TEIGKNQMDYHTVEFRAKNRSGEYIWLRCRGQLMRDEFGEPSIFAGIMTQLGKQNKID
                     SLTQLLNYHEFMSVFEDKISNPMIEKLCIVLLNIDDFKNVNEMYDRDFGDNIIKTLAQ
                     SIQSILPDNAELYKLDGDEMGILVDNVEENEILTLYDQIQNMIIHLQLWRKYGLNITI
                     SAGCVIYPKHGDTVKELYKCASYSLQYAKEHGKNRLVFFSQEILKNKMYSLEMMRDLK
                     ASINDDFRGFSLRFQPQVDTESHKIIGVEVLLRWTNDKCKAISPLEFIPILEENDMIN
                     IVGAWVLRMALRTFRKWIDYYPFFKVSVNVSAVQILEDTFIEDIVKIIDDENFPYQNL
                     VLELTESHTVQNMSILQFKFKALQDLGIYIAMDDFGTGYSSLEVLKFSPIDIVKIDRV
                     FVKDILKSKFDATFIHFIVAICHDVGIKVCLEGVETQEEYDLVKQIKPDYIQGYLFGK
                     PQTATEIFDLLKLDN"
BASE COUNT         9800 a         4221 c         3422 g        10431 t
ORIGIN      
        1 taaagataat ataaacatag gaggtacatt ctttgaaaaa cattatttca gcaaaagaac
       61 ttatatcaaa actagaaaaa aatgataatc tagttgtaat agattgcaga tttgatctta
      121 tcaatagaac ttatggtatt gattcttata aaaaaggaca tatcaaaggc agttttatct
      181 tagatataga caaggattta tcatctccta caaaagaaca tggtggtaaa aatcctttac
      241 aagacccttt aatactaaaa gaaaaattag aaaaaatggg tgttgataat gacactgcga
      301 ttgtaactta tgatgatgga gatttaaatg gagcttgcag attatttttc caattaaaac
      361 atttggggct taaaaatgtc tatgtactag atgggggaat aacatctttc gtaaaggaag
      421 gtggagaatt ggaagagaaa gtgaatatac caagttgtac aggtaaggaa attagaccaa
      481 atataaacaa tgatttagtt gttccaatgg aatatgttaa gtctaaatta tacaaaaaag
      541 atactgtaat aatagattgc cgtgctaatg agagatacca aggtttagtt gaacctgctt
      601 actcaaaagc tggtcatata ccaagtgcaa aaaattattt ttgtaaggat ttaataaaaa
      661 gtgactttga aaatggctca cttaaagata tagaattttt aaaaaaattc tttaaagatt
      721 taaataatta tgatgaagta attttatctt gtggttcagg gatatctgct tgtgttaaca
      781 gtcttgctct tagagaactg gatatacctc acaagattta tattggtagc tttagtgact
      841 ggattagtta tgatgacaat gaaatcaaaa ctggtcaaga ataaggctca taatctatat
      901 aaaatcagca tatgataact taaattttgt aaaggcgtca gtcattgtag actttcgcct
      961 ttacttatta tttcatatac tctttaaatt tattatatat attttagttg ataatattaa
     1021 taaactgcaa tatgaccatc acatcttgac tccgtcccac aaatataact ttcctgttct
     1081 gttttaaata ttatttgacc tcgtcccatg tcaacagtat catgaattac ttttatttca
     1141 tgaccctttt caattaatga atctattata tgctttggca tctctggttc aacttctatt
     1201 tcttttcctt ttatccactg ccatcttgga gcatctagcg cctcttgtgg atttaatcca
     1261 aaatcaatca tatttgttaa cacttgaata tgtccttgtg gttgcataaa agctcccatt
     1321 acaccaaatg gacctattgc tttatcttct ttacctaaaa atccaggtat tatagtatga
     1381 taaggttttt taaatggttt tactacattg tggtgtttag ggtctaaatt aaaattattt
     1441 cctctactat gtaaagcaat cccagttctt ggtatcacaa ttcctgaacc aaaatttatg
     1501 taattgctct gtatatatga aaccatattt ccatccttat ctgcagtaca aaggtatact
     1561 gtaccaccac aatatggctc tcctgcagtt ggatacaaag cctctttatt gtcaattaat
     1621 aaacttcttt ttttggcata ctcttggctt agtaattcct gaatctttac cttcatatgc
     1681 tctatatcag ttacatatgt tttagaatct gcaaaagcta attttaaact ctctataatt
     1741 ttatgtatgt cttctacatt ttctatattt ccttctaatt ccaattcttt taatatgtta
     1801 agtgccatta aaactgttat tccatgacca tttggtggga tttcaaatat tttatatccc
     1861 ttatattctg tacttatagg ttctacccat gttggataaa aacactctaa gtcactcttt
     1921 cttatagccc cattaaattt tttagaatat tcatctattt tatcagcaag tcttcctcta
     1981 taaaagcttt cagcctgagt atttgccatc tcttctaatg tacttgcctg ttcttcacat
     2041 ataaatatat ctccagcctc tggagcttta ccatctttag aaaatgtatc aaaccatggt
     2101 ttgaactctt ctccaataag ttctttttca tagagttcat atgatttttt ccatacctta
     2161 gctacattag gagatactac gtatccctct cttgcatagt ttatcgctgg agataagcat
     2221 tccattaagc taagtttacc atatttttta tttaattctg accaagctgc gggtattcca
     2281 ggtacagtta ctgctccaaa cccatatttt ggcatttctt tcatattatt ataatttttt
     2341 aattccatat tttctggagc aaagccacta gaatttaaac catacaatcg tttttcttcc
     2401 tctatccaaa caagggcata tgcatctcct ccaatcccat tgcttgtagg ttctactact
     2461 gctaatgtgg cggctgttgc aactgctgca tcaacagcat ttccaccctt ttttagtatt
     2521 tcaagtccag cttgagatgc taatggtgtt gatgttgcaa ctgctccatt tttagcatac
     2581 acgacatttc ttattgatga gtatttatgt tggtaggcat taaacttcat aaatttcagc
     2641 tcctcgtcat tttttatttg atattctgct tagatttatt atataacatc aagtaatgta
     2701 actgatacaa aatatagact ttttcctaac tttaatttta tctttaaata aatatcttaa
     2761 actcaattct agtattttct atctgcactt aaataagtta ttttattcaa aacatatatc
     2821 taattctttt gacttaaaaa taatttattc ttttatcatg tttagagcat attttaaagt
     2881 taaaaaataa tatataaaat atcctataaa ataaatgact agagttatga taattggtac
     2941 aagtaatgac cttggtataa acttttgtgc tatagacata gcaaataaat tatgaactgt
     3001 acctacaact aatggcatta aaaatataac ttttaactgt tttgatatta ttttctcaat
     3061 atctttatta tttgctccaa gttttattaa cataatatat ctttccttat catcatatat
     3121 atttgataat tgtttaaata agattatact acctgtacat aaaagaaata ctacagacaa
     3181 aaatatgcct ataaacagca ttagaccact taattttatc aagttattat aactttcaat
     3241 acttgatgta aaattaaaag gataagtaaa tttcatattt tcacttacta tattttttaa
     3301 ttttaaagtc aaatccagtt cttttttttc attttttata tcaattaatc ttattaatct
     3361 aaaatttcca tgtaatttta actgattaaa tacgtcatct tttactacaa ttaaatcaaa
     3421 cgtagcttgt gaatttattt ctggctccaa gatgcttttt tgtactttaa acagatttat
     3481 atcatactca tttgtatctt taatatgcaa gtttattttt tcaatctcaa agtctttaaa
     3541 aaatattttt ttgtatgaat cagaaacata gtacacggat tcctttgaag ttaattcttc
     3601 ataattgtta ttctgatatt gtcttaattt tttaaaatca ctttctctaa taatatctac
     3661 agacgttcta tcttctatat aactatttcc atttttataa tacatttcaa tatttatatc
     3721 tttgtctata agttctattg ttttatcaaa gattatctta ttatcttttt tatatttata
     3781 taataatttg tcaatttcgt tatttacata agaatttcct aaatttatgg tataactgta
     3841 tttataattt tcacttatgt tcctatctat atcgtaataa agtgatatgg taaaccctag
     3901 catagttaca cttgtagcta ttaatattgc tattacagcc aatacactac tattgctctt
     3961 taatttaaat ccaagttcag aaaatgcaat taaattctgt cccttataat aaaaactttt
     4021 tctcttctta acagcatcaa taatcatata catcgttgat gaaaaaaata aaaaagttcc
     4081 aggtattatt gtaactaata taaaaactga aagcataata ttttcagcaa taaaataact
     4141 aattgacatt aaataagaaa tagctattaa taaaacacca agtacacatt ttaactttat
     4201 aaatttttta aacttatact tttctggata tttattaaat aactctataa ttctcttatt
     4261 tctgataact atagtatttc ttattccaat aactataaat attattaaaa ataccgctag
     4321 tgtcttaact aaggccttta tacttaagtt catatttact actatcattt cattcattaa
     4381 ttttacaagc atcatagtca taagctttga aaataacagt cctaaaaata tacctattag
     4441 tattgcaact atacccatca aaaaagtttc atataaaaat atttttccta tctgattttt
     4501 cctcattcca agtaaactat aagttcctac ttctcgccta cgtctattga aaaaaaatga
     4561 gtttgaataa tatataaata aaaatacaaa taccactatt acaattgaac ttgtattaat
     4621 actcatccta gttttttctc caagtgaact caacgcttca ttatactcta tagatttaaa
     4681 actaaaaaat acaaatacac taaatacaat tgaaataaag tacattaaat aattaaaaaa
     4741 actattcttt acattttgca ttgcaattct aaataaagtc atttttatta actcctccaa
     4801 ttaaggaaac tgtatttact attttattat agaactctct gttactttct ccctttacaa
     4861 tttctgtgaa tattattcca tcctttataa agagtattct attgcaaaaa ctcgcactta
     4921 tagcatcatg agttaccatc aatattgttt tattgctgtc tttgtttaat tttaatagac
     4981 aattcaacaa atccctagca gatttagaat ctaatgctcc tgtaggctca tctgcaagta
     5041 ctaatgatgg ttttgttgct atagctctac atacagctcc tctttgcttt tgtccaccag
     5101 aaacttcgcc agggtattta tctaatatag attctatatt taattctttt gaaatctctt
     5161 ttattctatt ttctattact gatacccttt cattttttaa agaaagaggc aacattatat
     5221 tttcttttat tgtaagtgta tccaaaagat tagaatcttg aaatacaaag cctagattat
     5281 cacgtctaaa atctgccaat tcattttgct tcattttaat agtattcttt ccatttatat
     5341 aaatatctcc tgatgaaggt aaatctattg tagaaataat atttaaaagt gttgatttac
     5401 cagcaccgga agaccccata ataccaacaa attctccttt ataaaccttg aaagttattc
     5461 ctcttagagc ttcatgtttt gaaccttttc ttccatactc cttttttata ttttcaacag
     5521 ataatatttc ttccatagtt aataatcacc tttcatcaca attagttatt tatcaattct
     5581 cacaaatata ttatatatat taaaatggct tctaaacatt taattatatt aatttaaggt
     5641 tacattttcg taagtattaa ttatacttct tcaaatttat tgcaattatg tttaaaatat
     5701 aatttatcaa gtaaaatata gttatattaa tataattatt ttaggtaata aggtagaaat
     5761 attttaattt atcaagtaga atatagttat gttaatataa ctattttgaa ttaggaggta
     5821 agaatgttta aaataatggt agttgaagat gacgtctcat tgaaaaatat catagcaaag
     5881 tgtcttacta aatggggaca tgatgttcat caaatagaaa atcttgaaaa tataatagaa
     5941 gagttcaaaa actataaccc agaattagtt ttattggaca taaaccttcc attttatgat
     6001 ggttttcatt ggtgtaatga aataagaaaa atttcaaaag ttcctataat ttttatttct
     6061 tcaagaaatt ctaatatgga tgtaataatg ggtgtaaatt taggtgcaga tgattatata
     6121 caaaaacctt tttctgtaga tgtcttagta gctaaagtta atgccctttt aagaagaact
     6181 tataattttg ttgataataa ctcaaatcag attattcaca atggtgttac tttagattta
     6241 tcaactgcaa caataaacta tgaagataat actattgagc taacaaaaaa tgaaatcaaa
     6301 attctccatg agcttatgaa atataaaggt cagatagtaa gtaggaataa actcatgaaa
     6361 aaattatggg ataatgattg gtttgtagat gataatacat taactgtcaa tgtaaataga
     6421 atacgctcaa aattaaatga aattggttta gaagatttta tagaaacaaa aagaggattg
     6481 ggttatataa tcagttaaaa caattctaag taggtgaatt tatgagcttt aaagattttc
     6541 tcaaggataa actaggtttt ttagtataca attttacttt cttaattttt acagtatcag
     6601 ttattatatt ttctcctgta gatgtttttc tgactgatac tattttatat atattggttg
     6661 taaatgttgt gtttttattt ttatatctat ttattagcta catcaagaag aacaaatttt
     6721 tagataagat aaaaaatgat acattcaaaa ttaatatgaa tgatatagaa ttagctagat
     6781 gtaaaaatga agaaaaaata tacttgaaca ttattaaaaa tcatcaatat caatgtaata
     6841 acataataaa taataatatc gagaaatttg aagaaaacaa agagatttta aatatgtggg
     6901 tacacgatgt aaagatacct atagctataa taaaactcat tcttgaacaa aatgaaaatt
     6961 taattgatga aaaaatttta gatgacatag atagtgaaat atttagaatt gaaaactccg
     7021 ttgaaaaaat tttatattta tcaagactcg aagattttca taaggatttt ttaattcaag
     7081 aggtaaatat tgaaaaaatc attagaaata ttataaaaaa atactcaaaa tattttattt
     7141 caaaaaaaat tattttagac ttaaataatt tgaattttaa ggttttatct gatgaaaaat
     7201 ggctatactt catattcgag caattattga gtaattccct aaaatactcc tcattaggag
     7261 ataatatatc tatctattgc aaaagaacca aaaattattt acaattaaga gtggaagata
     7321 ctggttgtgg tataaaaaag gaagatttaa atcgaatatt caataaggga tttacaggta
     7381 ataatggaag aaacaattct aaatctacag gtcttgggct ttatttagta aaagaacttt
     7441 gtgataagct tggtcataaa attgatgtag attcagagta caaccaatat acaaaattta
     7501 ctattacatt caaatgtgat ttatagtatc ttattattga tagtttattt tcattaactt
     7561 atattcaact tcttatagta attctatatg tacatcccag tatataatta agtagttttt
     7621 ataaaaagga ggaagacatg tcttttctaa aaaaatttaa aaataaaaga tttagaaata
     7681 acagttttaa aagtaacaac tttagaaata gcagttttgg aagtagtggc ttcaagtcta
     7741 aaaataaagg ttttaaaaac aatcccttta aaaataagag attcaaaata tatgcaggaa
     7801 tagcagtaat catactttta attctaggag ttcttgctta tgttgattcg aaaaacactg
     7861 aattacaagc taatgaaaat tttatcgaaa catatactat tcctgaaaat gaaaaaatat
     7921 ttataaatgg gatggttgtt cctaagcaaa ctaaggactt caatatatct ggagattatg
     7981 agttaagtga tgttaatgtt acaaatggtc agaaagtaaa tcaaggagac cttcttttta
     8041 ctgctaaaaa tccaactata atagcagaaa tagatagttt aaaatcacaa cttagtcaat
     8101 acaaaaaaca aaaaatatca ctttctgata ttgctgaaaa taaagatgct attgcttcta
     8161 taaatgcaca gataactgct ttaaactctc agatagcttc tctggataaa aaagcttatg
     8221 acagagttac tgctcctttt gatggcacag tatacttgaa tgaccaaact ggaaatccag
     8281 accaaccagt ttcatttatg actattcaag gtctagagtt ttatatgaaa ggacaagcaa
     8341 gtgaacaaga tttacctaaa atgaagattg accaaatggt caatatacta gttttttcaa
     8401 ctgaccaaaa gcttactggt agaataagtt ttatatctga taaaccatct actccaaata
     8461 ctgaaatggg agctcagcag aatacactat cttattatga tataaacata gcatttgata
     8521 atcaagaagg attagtaaat ggattccatc ttcaagcatc acttgaagta gctaattcaa
     8581 gctttaaaat accagcatct tgtgtactta aagacaacaa acactcatat gtatttaagg
     8641 atttagatgg tatattgaaa aagcaaattg tagatgtagc aagtcaaaat gatgattttg
     8701 ctgtagttag aggcggtctt gaacaaggcg atataataat aaaacaccct actaaagaaa
     8761 tgaaagaagg agacccagtt caaggcgatg gcgtaactgc tggttctaat aatggagata
     8821 ctactccaaa caaaaaagta gaagaagtta ctatggatgt gaattaattt acatatgtta
     8881 attaaattag aaaatattca aaaatattac aaagtaggga aagatgaatt acatgtttta
     8941 aaatccttaa atttagaaat tgaatctgga gaatttgtca tgataatggg taagtctggt
     9001 agtggtaaaa ctactttact taatatctta ggttttctag atgtatttga tgaaggaaga
     9061 tatatatttg atggaacaga tgtaactaat ttgagtgaaa atgaacgttc tgtttttaga
     9121 aatattaata ttggatttgt tttccaacaa tttaatttaa tagaaactct aaatgtatat
     9181 caaaatgtag agttgcctct aatttacaat aaagcactaa aaaaatctaa tagagaagaa
     9241 attgttaaag ataaattaag ttctgttggg cttttggaca agcttaagca gaaaccactt
     9301 caattatctg gtggtcaaca acagcgtgta gccattgcac gttgcctagc aaatgaccct
     9361 cagataatct ttgctgatga accgactggg gcattagata gtgaaactag cagagaaatt
     9421 atggagcttt taacaaggct caacaaacaa ggtaagacta taataatggt tacacatgat
     9481 caagatttaa ctaagtatgc aactaaggtt atacgactta aagatggtgt gtttacttcg
     9541 gaggtgtaat catgagttta ttaaaaaatt ctttggccaa tttaaaaggt cacaagcttc
     9601 gtgtatttgt agctttactc tggattataa taggaataac ttcagtaata cttgttagtt
     9661 ctataggtaa tggatttcaa aaagaaatta agaaatctgt aaacaatgta aaccctaata
     9721 aaactactat ttcgtttgaa tcagccgata acacaggtct tactgatgat atgagtattt
     9781 ttttaaaacc ctttaatgca aaagatttag aagaattatc atttgttgaa ggagtagaaa
     9841 gaatagctcc ttcaagagat gggtttaacc ttgattcagt ttactcttca caagcatctt
     9901 ttgataaaaa aactacgtat gttgatgttg gaccagtaaa aaaagattct aaaataaatt
     9961 taatttgtgg tagagatttt tctttagatg atgaaaaaag aaaagtaatt ttacttacat
    10021 tacaaagtac aagtgaaatt tttgaaaatc cagaagatgc cttaggtcat ggtatcaaca
    10081 taaatggaac tatatttgaa ataatagggg tattagatga ttctcagcaa aaccaagctg
    10141 gaggattctt tggaggttac caagatatgc aatttactac ttccctagta cctaaaaagg
    10201 cttttgacac tttaatgagt caaaattctt attcaaatga aatttaccag ttagacttag
    10261 tttcttctaa aggctataat gtaaatgaag ttgcaaacaa tgttatagct aaattatatg
    10321 agatgcaccc tggtatcaat ggttcttata ctacaccaga cccaactgaa cagacagctt
    10381 atcttgaaag cattaattcc aatgtaaaca aatatgtatc tataataact gtagttgcaa
    10441 tgtttgttgg tggtattggt gtaatgaata taatgtatgt atctgttatg gaaagacaaa
    10501 gagaaattgg tataagacgt gctattggag caaaacctag gtctatatta tttcaatttt
    10561 tagttgaagc tgtttttata acagtatgtg gtggaatttt aggaactata gttggatttg
    10621 ctgctactaa ctatgtttct aaatatatag gttttgaagc tatacctagc ttaaatagct
    10681 tattttatgc aattgtagct actatattga ctggagttgt atttggtctg attccagcct
    10741 ttaaagcctc taaactagac cctataaagg caatttataa gtagaaattg tataaagatt
    10801 ttcgattttt agattagttt atataaaaca tacttaaata tataacgcac tattatatat
    10861 gatagattag gaacttaatc tttccaaata taatagtgcg ttctttcata aaaaggattc
    10921 tcttccttac tatatctaaa ttaccaagat gttatgttct aattgttcaa actaatactt
    10981 ccaattttga ttaatcaatc tcattctgct aatatacaat cttttacttt caatcattgt
    11041 acactccgcc ttaaaaaaat aatcttaaat taggcgttat atacaatctc cccattacat
    11101 attgtataat taacctttcc atataaagat ttacctttaa acggtgaatt atcagcttta
    11161 gaaacaaagc tttcaactgt ccattcttct tctggattga atataacaat gtctgctaca
    11221 gccccttctt ctataaatcc aatatttaaa ttgtacaact ttgcaggatt tatagacatt
    11281 ttttctatta actgcatcat actaagatga tttttatgca ccaaatttgt tattccaaga
    11341 gctaaagaag tttcaagccc aataattcca cttggagctt ttataaactc tctatctttt
    11401 tcttctttac tatgaggtgc atggtccgtt gctattattt caatagtacc atcatttaat
    11461 ccctctataa tcttatctct gtcccattta cttcttagag gtggattcat ttttgcattt
    11521 gttccaaact ccaatacatc ttcctcagtc aatgtaaagt gatgtggtga agcttctgca
    11581 actacatttg cacctaagta ttttgcaaac ctaaccatat caacagatac acctgaactt
    11641 atatgttgta tatcaacttt agcaccagtc tttagtgcca acatacaatc tctggctatc
    11701 ataacatctt ctgctacact tgatgcacct tttaatccta gttctgaagc tacctttcct
    11761 gcatttacac ctggatttcc aactaaagaa gggtcttctt catgaaaact aagtggtaca
    11821 tccaactctt ttgccttaat cattgcctcc ataattagat tgctatccat taaaggtaat
    11881 ccatcatcag taaaccctgg tacaccagct tttttaagag cttccatatc aactaactct
    11941 ttaccttcaa aacctttagt tatagctgct gcttgtaaaa catttataca tgcatttttt
    12001 gacttttctt taacataatt aaaagtatct tcattatcta caataggatt agtatttgcc
    12061 atacatataa cagttgtaaa tccacctcta gcagcagatt tagctccact ttctatatct
    12121 tctttatatg taaacccagg gtctctaaag tgtacatgta catccactaa acctggagca
    12181 actacattac cactagcatc tattattttt tcatattcat cactttcatc aaacttgcct
    12241 attttataaa ttttattttc ttttataatt aagtcaatat tctcatctct ttgactttta
    12301 gggtctatta ctctaccatt tttaattaaa atcatattat ttctccttta tatttttaat
    12361 ttatatagac tcatataata ttatacatta ttttacatac ttaaatacaa aattacgttt
    12421 gacatcaata gcctttttag gacaaagttc atggcaacag taacatctta tacatttact
    12481 taagtctata atagcacctt tagtccctat ctctatagtg gatgcaggac aagcttcctt
    12541 gcattttcca cattttatgc aatcttgaaa tcttaccaca ggctttggtg ttataagctt
    12601 tgaaataggt tcatttaaaa attttggtag ctttacggaa aacaatctta aatccttact
    12661 tacatttgga atcttgtaat tttttataat taaatctttt atatcttcac ctaaaatttc
    12721 aatatctgaa aaatcttctt gtatatagcc tctcttaata gcacctctaa ttgtagcaac
    12781 tctatttgga agtaaactta taatcttaca tgcaacaaca tctatagcat atggattttg
    12841 tgatgctaat aaaactccta tttctcgagt agtaccagct gaaggtccat caccttccat
    12901 acctactata ccatccataa ttgtcaatgt tggttttata taatcacaaa tatctaaaag
    12961 tacattttcg caaaacaact cttctgtagg aaatctataa tgtatctctg cttttttcaa
    13021 tcctgctatg catccatata agttttttgt accaccagta aaggttgcca ttatatgagt
    13081 ctttaattta caaagattta ttatataatc tgaatctact attggtttaa taatatccat
    13141 atattttaga acatgtgctt ttttactatg tatcttaaca tctgaaacat cataatttaa
    13201 cttaatgccc agttcatttg ctacttcttc aattccagat gccttataaa tgctcttaag
    13261 agaattttga ttatatggac caccagggct atctgctatt gtaatatcac aatttaactc
    13321 taaaagtttt tcacatacaa cttttacaac cataggatgt gtagttgtag cttcttcagg
    13381 cttttttttc attaataaat ttggttttat aagtactttg cttccttttt taacaaactt
    13441 atctatacca ccaatatcct ctaaattttt ttcaatagat aactttactt cttcataatt
    13501 gtaagtttta caactcctaa cagataccga cttcatatta tctccatcct tctatcacaa
    13561 cagtttattt gtataattta aaaaaggaga aaccaaagtt tctcctttta atctatgttt
    13621 taattattat tttccaaaat gtctgtttaa taatcctaag aatgctttac catgtctagc
    13681 ttcgtcttta cacatttcat gtactgtatc atgtatagca tctaatccta attctttagc
    13741 tctcttagct aattttaatt ttccatcagt tgcaccatac tcagcatcaa ctctaactct
    13801 taagttttct tttgtatctg caactacaac ttctccaaga agttctgcaa atttagcagc
    13861 atgttcagcc tcttcaaaag ctattctctt atacgcttca gctacttctg gataaccttc
    13921 tctatcagct tgtctactca ttgctaaata cattcctact tctgtacact caccagtaaa
    13981 gttggctctt aatccttcga ttatttctgc atctacacct tgagctactc ctattctatg
    14041 ttcatcagcc caaaccattt cgcctttcat ttcttcaaat ttatcagctc caactttaca
    14101 tactggacat tgtgctggtg cagcatctcc ttcatgtata tatccacata ctgtacaaac
    14161 aaattttttc ataattaatt tcctcccaat tttatataat taaattttta tttttaagtt
    14221 taataacttg ctacaagaat atatataccc cagactttat agcttaaaca ctaaaaataa
    14281 aatttatttc ctaattaatt ttatcacttt gaaacaccag tatcaaccaa gttttgatgt
    14341 caaatttcta cataatacat aatttatttg attaattagg aaatagttgt catattaaat
    14401 actttctaat gaagactcct ctgaatcttt aagtttcact tttttgctct ttaaaaaaga
    14461 taatttagtt tctgcagtta tgattgcaac aaatatcaag atactaccaa taaccaattt
    14521 tgctgtaata agttccttta gaattattat agaaaatatt gtaccaaata cagcctctgt
    14581 ggataatatt atagctgttc tagttccatc aactcttttt tgacatatag tctgaaataa
    14641 aaatccaatt gtagtactaa atacagctag atacatagtt cccatgtaac cagataattc
    14701 agcttccatc tttaattgac ctgcaaatgt ttgaactaca acagacatta aaaacgctac
    14761 tgtaaattga atagctgtca atgccattgg gttgttatct tttgcaaact cacttgtaaa
    14821 gaatatatga aatgcaaatc cgaatgaaca tataagtgtc agaaaatctc caaaattaat
    14881 agagaaatca gcttctaaag aaagtatccc aattcctata agagctacca aactacttat
    14941 tattcctatt ttatcaagtt ttcttctata aagtataaat cctatgaacg gaactattac
    15001 aacattagct gctgttataa atgcattttt agatggtgta gtgtacataa gtccaatagt
    15061 ttgtactgtg aatgctagaa ataaaaatat tcctaaaatc cctcctgctt ttaataattt
    15121 tttacccata ttggcacgaa tctgtttaaa aaacagtaaa ttcataatta tagctgccaa
    15181 gaaaaatctt aaagttatga tttgtagagg tgtaagccca ccgtctaatg caaattgggt
    15241 tgctacaaag ccacttcccc atataattgc tataaatatt agtcctattt ctccaaagta
    15301 ttttttcaat aaagccccct cctttttatt tttttgcaaa attataaacc ccctaaacag
    15361 caagagagtt tttctataag cattactata aattaatata gtaaattttt tcagtatttt
    15421 aaatctaaat ttacatacat tttgagctca aatttatatc cactatttaa cagtaatata
    15481 ttaatcattt tttgtaaaca cctttttaat aaatttttat attttttata tttttttacc
    15541 tatactaaat ttttttatag atatttttaa tatatatgat actttaatat tatgcaaata
    15601 atgtcatata agttacactt tagttatctt agttacaact ttgtcggttt actttttcta
    15661 ctttcttcga tataattata atatattttt gatacaattc gacaaaaggg ggaatgctgt
    15721 aattatggta aaaaaaagaa aaaagaaaac tgttacactt actatacttg ttgtaatagt
    15781 tattggtatt ttttctatgg catgggcgga catgtctaga aaaaaagaaa tgaaagaaac
    15841 tcaagaaaga cttaaagctg aaagattaga aaaagaaaga attgaaaaag aaaaaaatga
    15901 acctattatt ggtgcaaaaa aagaagctgt aaaagaatat ggatatgacg caaaaatagt
    15961 ttgggacaaa cttaacaaat acgactattc aaacaatgga gaaaagatag tctttcttac
    16021 atttgatgat ggaccatcta ctactaatac tccacaagtt ctagatatct tgaaaagaca
    16081 tggtgttaga ggaactttct ttattaaggg tgattctctt gaaagaaaag gagctaatga
    16141 aattttaaaa agaacatttg acgaaggaaa tgcaatagcc catcactctt atactcatga
    16201 ctataaaaaa ctatatcctg gcagaagcct aaatctcgat acattcgtaa atgaacttaa
    16261 caaaactgat gaagctatga aaaaagtctt aggaaagaat ttttcctcaa atgtagttag
    16321 atgcccaggc gggtatatgt catggaaaaa tatggaacct ctaggaaact acttaaaaga
    16381 gaaaaacatg gcatcaattg attggaacgc tttaaatgct gatgcagaag gtaaaaagaa
    16441 aaatgcacaa gaattatttg aaaatgcaaa gaaatcttct gaaggcaaag aaatggttgt
    16501 tcttttaatg catgatactt atggaaaaca agaaacagta aatgcattgg accaaattat
    16561 aacatatttt aaagacaatg gttatcaatt taaaatttta atataataaa aaagcaagtt
    16621 tattgaatgt acattttata ctcaatagac ttgcttttac tttactctat tttactagct
    16681 cgatttttac aaattttttc tttcctattt gaacaactaa ttcactctct tttacaatag
    16741 tgcttaaatc ctctactttt tcaccattta cctttactcc accttgagaa gctaatcttc
    16801 taacttcact cttactctta acaatctcat tagaaactag tacttcgatt aagtcaaatc
    16861 catcttcttt aacttgaatt gtttgtatat cttcaggtat ttgacctttt tggaatacag
    16921 atttaaatct ttcttcagct tctttagcag attcttctcc atggtataat gttactattt
    16981 ctcttgctaa gttcatcttt atatctcttg gatttactga accctctttc aactgagatt
    17041 ctattttatt aacttcatca ggatgaacat ctgtcactaa attgtagtat ttaattataa
    17101 gttcatcagg aatttccata gatttttggt acattattcc cgcttcttca tctattccaa
    17161 tatagttacc taaactctta ctcatttttt ctttaccatc taatccttct attaaaggca
    17221 tcattattac tatttgagac tccataccaa attctctttg taatgatctt cccattagta
    17281 aattgaatct ttggtcagtt ccaccaagtt ctatatcagc ttctaatgct atagagtcat
    17341 atgcttgcat taatgggtag aagaactcat gtactgatat tggcatttgt ccttcatatc
    17401 tctttttaaa atcttctctt tctaacattc tcgcaacagt aatagttgct gctaatttta
    17461 ttacatcttc aaaatttaac ttggctaacc actcgctatt aaatcttaca atagtttttt
    17521 ctttatctaa aactttgaaa atttgttctt cataagtttt tgcatttgca agaacttgct
    17581 ctgttgttaa agcttttcta gctttagatt ttccagttgg gtctccaatt tttcctgtaa
    17641 aatctccaat tattattact atttgatgac ctaaatcttg taattgtttc atctttctaa
    17701 gaactactgt atgccctaaa tgtatatctg gagcacttgg gtctagaccc aattttacta
    17761 tcataggctt tccttctttt tctgatttaa taagcttttc ccttaactct ttctcatcta
    17821 ttaaatcatc tacacctttc ataattattc gcatttgctc gtctatcgat ttcatttttc
    17881 attcctccta aaatatttat ataatctata atttttattt ttataataaa aaaagctttc
    17941 atcctcttaa aaggacgaaa gcattgctta cgtgttacca ccttagttca tcaacatctc
    18001 acgatattaa tctcttagag tacaattaca tatactcgtg tactataacg tgtactaatc
    18061 cgatatctct taatggttgt tatctttcag agatagtgct ctgagatgta ttcaaactaa
    18121 atcaatttat tccatttcac caaactggaa ctctctgtta aataaaatct agccctactt
    18181 cttctcttca tagcatttat atattcagat tatttcatca attacaagaa atttttctta
    18241 acttactcat aatatattat tatttttata ttttgtcaac cttttttatt attatataca
    18301 tgttttttta cattatacta cttttttata ttttttacca atacccaaag tttatttttc
    18361 aatcaaaaga tttatttgtt tattgactat attactctga ctcaatctta tatttatttt
    18421 cttatttaaa aatgcgttta taattattaa actaataact gttacatcaa atataaaaaa
    18481 cagcaataaa attattatca aaaataaaat tctagcatat aataattttc taaacttagc
    18541 tattataaag ttttgtagtg acatacatga gtctctaatg ataaaataga cacttatata
    18601 ggttattgat ataaagattg tttttaaata aacagaatca actttaacat tcaacagttt
    18661 tagaacttca aaaatggcta gataagaaac acatatgtaa aaagcttttt ttgagcaaca
    18721 taaaaattgg tttaaacttc taaaattctt aaatattaaa aattttttta aagaattaga
    18781 atctaaaata tgcaatttat tccctaaaat taaacttaat aaatatatgc aaaacaccat
    18841 accaaaagga aacaatgcta tcattaaata ataaataaaa tttgtacacc cattaaaata
    18901 aatccatttg ctatatcctt gaaattcttt cataaaacta taacctatta atgttgaagc
    18961 atatatatca atgaaaacca ttacaataac cccaaatact gaaccatata ctaaatcatc
    19021 cataaccatt gtaggcttat ttattagata gccacacatt ataccaagta atacactctg
    19081 acttgcccaa atagcagttc ctagatttcc aagtaccaga gaaattatta aaagtgaagt
    19141 aattccagat aaaatggtat actttaaatc acatttcaag cagattatac aaaaaaatac
    19201 tggcactata aaatctaagt aaatagcata tccaaatcca gtactcacag ctataattgt
    19261 tactactatg aataaagatg acaataaagc tgcttcagtt aattttttag tagtattcaa
    19321 aacactgcct ccataaatca taaattttct aactaaagtt ttgtttttaa tatagtatat
    19381 cactttttaa aaatattttt aataaatata aattttaata aaggtattta tgttaaaaat
    19441 ggtataatgt atcttaatat tcagtttttt aagatgctag gaggtaatta ctatgtttaa
    19501 aattaaacac tttaatgatt tgagtttaga tgaattttat gaaatagcaa aatcaagata
    19561 tgaggtattt gcttgtgaac agaagatatt ttcattaaac gattatgatg atatagataa
    19621 aagctcttat cacatatttt taaaagaaaa tggattgatt tgtgcttatg ctagaataat
    19681 tcctaaagaa tacagctctt ataatgatgt ttccattggt agagttttag ttctttctag
    19741 tcatagaaga aaaggattag caaaacaaat gatggattgt gctatagatt ttataaaaat
    19801 taacttacac gaaaataata taaccttatc agcacaaact tatataaaga acctttactt
    19861 atcttgtggt tttaaagaaa tctcagaagt atacgacgaa gcaggtattg aacatattaa
    19921 aatgagatta tagtgttgac aagctaatat tgttaatata taatttaagt ataaattaaa
    19981 tattgaattg atatttaggt atttgaaaat accttacata gagtcaggag gcttttgctt
    20041 tctgactttt ttattatcaa aattcaataa ttatatggat tcaaagtgtt aatttttatt
    20101 ctatattcta ctttccccaa aagtaagaat tatacccaac tttgtatgat aggcatcttg
    20161 cctatctttt ttttgtaaaa gtaacaaggt aataatataa tgcatagttt agaataagaa
    20221 gattagccca ggctaaattt caagcatgga ggtgctacta tgaaaaacct taacgatatt
    20281 caagtgaaaa aaactgtcaa agttgaagat atattatcta gtggtaattt aagagaaaga
    20341 atgttagcgc ttggtcttac tagaggagct gttatagatg tagttagaaa aggtccaaaa
    20401 aataatttaa ctgtctataa aatcagaggt agtaagatag ctctacgaca agaagaaagt
    20461 agcttaatat tagtttctga catttaaaaa tttctagcag gaggatatta atatggggtt
    20521 gacacataac tcaactaaaa tgagttcttt aaaagatatg tttgatatag acaataagga
    20581 agaccagttt gtaattgcat tggctggcaa tccaaataca ggtaaaagta ctgtatttaa
    20641 tcatcttaca gggcttagac agcatactgg aaactggcca ggaaaaactg tagctacagc
    20701 tcgtggtaat tttaaatata aaaataccga atatgcatta atagatttac caggaacata
    20761 ttctttattt gccttatcac aagaagaaat tgtagctcgt gattttatat gttttggtaa
    20821 tccagatgca gtaatagtag tatgtgatgc tacatgtctt gaaagaaatt taaatttagt
    20881 atttcaagtg atggaactta cagataaagt tattttgtgt attaatttaa tagatgaagc
    20941 tagaaaaaaa ggcattacta ttgataaaaa acttttagag gattctcttg gtattccagt
    21001 tattttaact gctgcaagaa atggctctgg tatggatgaa ctattggata ctttaaatga
    21061 tgtatctttt gacaaataca aattaaataa taaacctgtt agatacaatg aaaatataga
    21121 gaatgtggta aaatcaattc aaccagaatt ggataatatt ataccaggta taaattctag
    21181 atggttggga cttagactta ttgatggcga tgaaagtata tttgaatcta tgagtaatta
    21241 tatagacaaa gattctatag atgctattaa tgaagtaaag aaaaagattc cagacaatat
    21301 aaataaacag aaaataagag atgagtttac taaaatcaac tatgattatg ctaaaaaact
    21361 gagtgatgag tgttgttcta atgttgctaa aaaatcaact gatagagaag aaaaagtaga
    21421 taaaatatta acatctaaaa tatttgggct tccaataatg ctcttattat taggtactat
    21481 attgtggatt actatagaag gggctaacta tccatccact ttattatcta atttattact
    21541 cggatttgag ccaagtattt cgggtatatt aaatagtatt aattgtccat catggttaaa
    21601 tgatatgttg gttttaggat tatacagaac attagcatgg gtaatctctg taatgctacc
    21661 tcctatggca atattttttc cattatttac cctacttgag gattttggat atttgccaag
    21721 agttgcattt aacttagacc acctatttaa aaaagcttgt gcacatggaa aacagtgttt
    21781 gactatgtgt atgggatttg gatgtaatgc agctggagtt attggttgta ggataattga
    21841 ctctccaagg gaaagactta tagctatact tacaaacaac tttgttcctt gtaatggtcg
    21901 ttttcctact ttgatagcta tatctacaat attttttagc tcagttataa ccaactcttt
    21961 cgtatcaagc gtagcaactg cactttgcat aactttactg ataattctag gtgttataat
    22021 aacattgttg gtttcttata ctctttctaa gacgctatta aaaggagttc cgtctacatt
    22081 tacattagaa cttcctcctt atagagttcc tcaaatagga agaactttat atacctctat
    22141 aatagataga acaatatttg ttttaggaag ggctgtaatg gtagccatac ctgctggtgt
    22201 cataacttgg atatttgcaa atatatatat aggagattta agcatattat cacatgttgc
    22261 aaacttttta gaccctttag ctaaattaat tggtcttgat ggttttatat tacttgcttt
    22321 tattcttgga ttcccagcaa atgagatagt tgtacctata cttttaatgg cttacctagc
    22381 aactggttct atgatagaat tagatagctt tagtgcttta ggtcaagttc ttagagaaca
    22441 tggatggact tatttgacag ctttaaatgt tatgctgttc agtttactgc attggccttg
    22501 tgcaacaaca cttttaacaa taaaaaaaga aactggtagt ttaaaatgga ctgccttagg
    22561 attcttaatg cctactatac ttgcttttgt tgtttgtttt ttaacaacta cagtttacaa
    22621 tttatttata taattagtat taactgacat tagacatata ttagagaaac tatttaaaaa
    22681 tttatatact ttattataaa gcatagagat atattcaatg ataagtaaaa ttacttaaca
    22741 tttgaatata tctctatttt aattcttatc tggatacttg aattgaaatt tcagtcatat
    22801 aattatcttc attactttca caaaaaaagt caagtatact ctcctcatac gaatttccaa
    22861 taattttata ttcattttca tatatatatt ttttcaattt ttcgtaagat ttatatgaat
    22921 cctcatattt tccaatatgt tttatgcaag catacattcc ttctggcttt acatatagct
    22981 ttttatcctt tattttttta tctatcttca aataaaaact tgatatactt aaatagtccc
    23041 cattttttat attttcatta cttactatta ctcccaactc atatccttga tacaaatttt
    23101 tcgatttaca ataattggtg aaatctatta attccatcat aaaatcacta ttactcatat
    23161 tactcaaatc gcttgataga actaaatatt cttcaaactt tttggatata taaatttctt
    23221 cactattcat tttagaaatt ccttcaactg ttatatttat tctattttgc atcttagagc
    23281 ttatctttct tagttttttt attttttctc ttatcttttt ttcttcttct ttaagcattt
    23341 tcacacaaag ctggggagtt ctattttgta tatactcttt tatttcctct aaactcattc
    23401 ctatttctct taatgattgt aatatatcaa gtgtatcata ttgataaact gagtaatatc
    23461 tataattatt tttatcttta tattcaggag aaaaaatacc tattttgtca tagaaaatta
    23521 atgtctgctt agatatacca cacaatttag caaattcacc tgttgtaaaa tactgttttt
    23581 ccaagggtta tacactcctt ttctttttgt tgtctatata gttactatat tctttattat
    23641 ttactaaatc aagtagttat tattttagaa aatcaatatg gttttgattt taaagcttaa
    23701 atgtcagtta gatgtcagtt ataaatattt tatccattcc catcataaaa aaagatatac
    23761 cctcttaact tttggatgga atattatatt tatgcttgtt agagtgaaaa ttgtaatagg
    23821 tgctacaata agatatttaa ttaaacataa agttaattat tgtaataaaa aatctttaga
    23881 taaattagag ttaaagtatg gaaatataga tagagaaaaa gctgttaaac tagaaatatt
    23941 ttatcaatat ttaatagaac ttgaatatat agaaatgagt ttattaataa gaagattaga
    24001 tactgcaata acatcattag cattagtatc tattataaca atagcatcat attatttaat
    24061 cagaaaaaat gtgtaattat gtaagctatt tataataaaa cactgataaa attaataata
    24121 aaaaggtaat aggatttcta tactaccttt tggtttttat aatatagtgt aattttatta
    24181 tatttttgta tgctaatata actagataat cataagataa cacattaaaa gaaaattata
    24241 aaaatttata ttccatatag ttaatataaa acgtagcagt tgcactaaag aatatgtaca
    24301 agataaataa atttacattc catatagtta atataaaaca ggagttgtgc aggatataac
    24361 atttcaaaca tcagtattta cattccatat agttaatata aaaccttgtt gcatttgatg
    24421 aaacagtaat aattattttt tcatttacat tccatatagt taatataaaa ccatatgtaa
    24481 caccttttgc taccccaagc tctttataat ttacattcca tatagttaat ataaaactat
    24541 tacaaaaaat ggatactagt attaatgata tacaatttac attccatata gttaatataa
    24601 aacgttgtaa ataaaccgtt tgcttttagt gttgatgtct gatttacatt ccatatagtt
    24661 aatataaaac taaatgttcc ttcaagttat aactcgatat ctgcagtatt tacattccat
    24721 atagttaata taaaacccca aaataaactt agtattttca atacttacac gtatacaact
    24781 ctcttaaatt tgcagtgaac gagcaatagt gcaattgata acgcttatca tgcactctca
    24841 acaccttata tttcaactgt tacgccaaat tttatcacaa atatcgatca ctgcaaaatt
    24901 tctataattt tattatatca taaatatatt acttttgaat attgatacca atttatacca
    24961 taataaaagc aagaaaaaac gtaatctatc tacattggat ttaaattcta taacttaaag
    25021 ttttttacat aatatttatg cttgtttaat caatctaata tatcattctt gtatattgct
    25081 tttaatagtc ttttttctta aataaatatc tatctgaaca agcatagttt aattaaaaac
    25141 ttttgtattc ccttaaaact gtatctacct cttattattt tatttatgat atattatttt
    25201 taatctaaaa atagatatct atttttatta tagttatccc tttttaaaat actttaatca
    25261 tatactactc ctaatttaac atcccttgaa atgctatttt cttatattgc aatttataat
    25321 tgatatatct tcaatataat aatttaatgt atttttgatt ttaaagcttt tcagtgatat
    25381 tattgataaa ttagaattaa ttatctagct ttaaaaggtc aaagatttct gttgctgtct
    25441 gcggttttcc aaataaatat ccttgtatgt aatctggctt tatttgttta actaaatcat
    25501 actcttcttg tgtttctaca ccttctaaac atacttttat tcctacatca tgacaaattg
    25561 caacaataaa atgtataaat gtagcatcaa acttactctt taatatatct ttaacaaata
    25621 ctctatcaat tttcactata tctattggag aaaattttaa aacttctaga gacgagtatc
    25681 cagtaccaaa atcatccata gcaatataaa ttcctaagtc ttgtaaagcc ttaaatttaa
    25741 actgtaaaat actcatattt tgtactgtat gactttctgt caattctaaa acaagatttt
    25801 gataaggaaa attttcatca tctataattt ttactatatc ttcaataaat gtgtcttcta
    25861 atatttgaac agctgaaacg tttacactca ctttaaaaaa aggatagtaa tcaatccatt
    25921 tcctaaaagt acgtaatgcc attcgaagca cccaagcccc tacaatattt atcatatcat
    25981 tttcttctaa tattggaata aattccaaag gagaaattgc tttgcatttg tcattagtcc
    26041 accttaaaag aacttctaca cctattattt tatgactttc tgtatctact tgtggctgga
    26101 atcgaagact aaacccccta aaatcatcat taattgatgc ctttaaatcc cgcatcattt
    26161 ctaatgaata cattttattt tttaatattt cttgggagaa aaaaacaagt ctgtttttac
    26221 catgctcttt cgcatattgt aaagagtaac tagcacactt ataaagttct tttactgtat
    26281 ctccatgttt tggatatatt acacaaccag cagaaattgt tatatttaat ccatattttc
    26341 tccatagttg aaggtgtata atcatattct gtatttgatc atatagagtt agaatttcat
    26401 tttcttcaac attatcaacg agaataccca tttcgtcccc atcaagttta taaagttcag
    26461 cattatctgg taaaatagat tgtatagact gtgctagtgt ttttattata ttatctccaa
    26521 aatccctatc atacatctca ttaacatttt taaaatcgtc aatatttaat aatactatgc
    26581 ataatttttc aatcatagga tttgaaattt tatcttcaaa tacactcata aattcatgat
    26641 aattcagtaa ctgtgtcaat gaatcaatct tattttgttt acctaattgc gtcattattc
    26701 ctgcaaaaat acttggttct ccaaattcat cacgcattag ttgtcctcta catcttaacc
    26761 atatatattc tccactacga tttttagccc taaattccac tgtatgataa tccatctggt
    26821 ttttacctat ttcagtgttt gacttataaa aacgattcca gtcttctgga tgtacaattt
    26881 ttttccagta aataagcgga ttttcaacaa tttctcctgg taagtcaaat aattcaactt
    26941 gtgatggtga atatcgaaat acgcctgttt ttatattgca aatgtatata tattcatctg
    27001 tacctctaat caaagcatca taaagcaatg tagaattata atcaaaattg tctcttgaaa
    27061 aattaaaaac tcctttttct tctttattat ttgatatttc atgaaattca ttaatcttaa
    27121 ttggtttatt taagcttgtt gagtttgcaa tatctattga ttgatgcata tgaacaactg
    27181 tgccatcttg acatgtaatt aaactatcat aattttcaaa aacacgattt aacttattac
    27241 attttccata ccacgttatt aatactcctt ttttatcatt ctttaataat tctaaaactt
    27301 tacaaaaact acaagtagaa tttttttcag gatataatac ttgccaacaa acttttcctt
    27361 ctggatctaa aatattatat tcttctttca ttttttcgtt cataaaaata atttcattag
    27421 tatggatatt tgtaacatat atattaatct gtagttgatt taatataact tcaaaattat
    27481 gtttgttcat atacttatct cctccatagt tactgctctt tataacaaca ttgttaaaat
    27541 tattcttttt agaagattta cttataattt atacatgcac actaaatgcc ttaatttaat
    27601 tagaaaattt attacttcat attttaaatt ataattgata aaaaaaaata cagcaatata
    27661 gtattaccaa tttaaaagaa attaatatta cataatactt ctctctctta tattaaattt
    27721 taacttggta ctaatcttga caaattgtcc acaaaaataa attatatatt ttattattgt
    27781 tttaaatttt tataaaaaat cagtattatt tatactattg gagttaaaaa gcattaattt
    27841 ctaaaaacat cataattttt ctaatagact taat
//
LOCUS       DACTZW010000052        27737 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.052, whole genome shotgun sequence.
ACCESSION   DACTZW010000052 DACTZW010000000
VERSION     DACTZW010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27737
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.052"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            46..120
                     /locus_tag="JAM15_11815"
     tRNA            46..120
                     /locus_tag="JAM15_11815"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:78..80,aa:Thr,seq:tgt)
     gene            complement(280..957)
                     /gene="srtB"
                     /locus_tag="JAM15_11820"
     CDS             complement(280..957)
                     /gene="srtB"
                     /locus_tag="JAM15_11820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtB"
                     /protein_id="HAT6798940.1"
                     /translation="MKKLYRIVINIILVLVILYSGFNIYSKLTKYNHDTKTSSELQKK
                     EYKKEDLSKINSDFKFWLSVENTNINYPVVQSKDNSYYLDKDFYKKDSISGTLFMDYR
                     NKSIDDKNIIIYGHNMKNKTMFNNLNKFKDADFFKNNNKIKITLNGKEFLYDVFSAYI
                     VESDYDYLKTNFNNESDYQNYINDITSKSLYKSPIKVNSNDKIVTLSTCTYEFDDARM
                     VIHGRLI"
     gene            1089..1424
                     /gene="rnpB"
                     /locus_tag="JAM15_11825"
     ncRNA           1089..1424
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="JAM15_11825"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
     gene            1702..4245
                     /locus_tag="JAM15_11830"
     CDS             1702..4245
                     /locus_tag="JAM15_11830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPOR domain-containing protein"
                     /protein_id="HAT6798941.1"
                     /translation="MKVLSENNIIRNTVLNVTASFLKQESKINEKLDGVLEKKFEKVE
                     FNEAKYAELLKFNILFYKTLARNTEPLIGKWIVDKYIPEIDELEKDLELTTAKCRKYV
                     NKAMKEGLDSLKANDLNSFLAYDKMELSERRRRLEKDYKVLNLYKDLLNISLRKISLE
                     KKECGDLFLKNQADAKRELKREIIFCVNKILASNKDVVPNNVEENNEQDKVEIKATEI
                     EDLQLGKDNSENDMLLNEIKNSKVKHESKSNDIESKFIDKLNSLNNESISQTIHNEYK
                     KLCGLEELHSVEGYGFGKEIIKDFACATVVLEFLKRRNRDLIEGAMRLTIIGEFGPEN
                     FKEFVDYVIKNKTEISEDTWNKAQNLIKDNYSELENHEIASKRTRRNKDIDIEEYIYM
                     IKNADKDICFRSSISIEDDAEEGAKEEVDSNNQDIGDVVEDKDTTDKEYDSNKEDIIE
                     PENKKSKKKAKLFGFIKKDNEEVEQEEENLNDISPDIILDKPVENHQAKSEEIEQNEL
                     KEIKQEEPSQHIEEERSVKIEKPINNNLDEKVSSNNESKLEKESKNLEDKKAKEIKEE
                     KLENEKSVVIPIKKKENSNKKSKNSSKDKYRENKKEMKNYVSDKEDSLDDEEVVSKKS
                     RLKETIIAVVIVVIVGVGYFITVGNNKKNDKENIPKSSTQQQANNKLTEEEKKAQAEK
                     EKKEAEEKAKAEKEAQEKAQAEKKAKEMEAYKDGKGVYYTVYAGSLKVEKTAKETAKE
                     YEAKGISSTIIQENGYYKIKIGDYSQYGEAQEKCNELAKKSIDTYIAMYDKYYDYKLE
                     ELKESAPSLSAEELKQKYEDLRSELKNKSGYREYVKHLDKLYEEIVEGA"
     gene            4367..6358
                     /locus_tag="JAM15_11835"
     CDS             4367..6358
                     /locus_tag="JAM15_11835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798942.1"
                     /translation="MLKLGEKIIYELSDGFELSGISRYSKEYKKLHITNLGNIIISKS
                     DEVNEDTGVKYIYSFSDNKEKLEAVLEDSQIIVYGNNLPFYIKSENSSKNVTANLTMK
                     ITLDEYDLICKSQREFIFYLKDNMTILSLDDNKFYMGGINKDNEKFIFISGKNRFEIN
                     FDDIERYILEDKRVSLKGYFHMEREGIIVRSVSIFNNNIDSVVPSDLNERVKDNQKIG
                     NLPKDCDIVFCKISGNIDGFDYKNTNMLLVKYQDQLIFINKKSKKTIVKSAKDNCSKL
                     NLGEDIILYDNKNVFNLHINDKNREIMQIDDLKDIENEIVGYTLKHAPFFIQEDFDSL
                     TILKSFQKEIISIKNSDIKDIVINKELENENSNFVETEIKFNNQKVLLNLSKNMVQKL
                     MQDVFIYAKQPLLKENSIEVIYKNWSKAMNDMIIFNFFGNIYYMKSEFDKILEKELND
                     EIRIEVINSLYKQIQEQRNNLDLLSAYMPRILENQEIDLFEKYNTKLDVQVFKQIKNL
                     LSDLSYNISSYLNEVEKSLDNIIFVISGEDKKKYNYRMLKESESASLDVFLKQAISRL
                     NHLVENMYPYYVDETSREMFKLFELLWKNYRNIDDDSIKEILFERITNTYVFKQLTLN
                     NSTKERRKDIIEKIYNSVDYGTNKLDENMFFTGGIKYVK"
     gene            6348..6668
                     /locus_tag="JAM15_11840"
     CDS             6348..6668
                     /locus_tag="JAM15_11840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6798943.1"
                     /translation="MSSKYNVWTFNYEFLGLDSGDEKNNEVYYEIDLDEILNENYIDE
                     DIDSGLDSDGNSILGELISEMDIDEDVSVDMTYQELEVDLEDLDSYLDEDIDSDIKGI
                     LDEI"
     gene            6860..7735
                     /gene="galU"
                     /locus_tag="JAM15_11845"
     CDS             6860..7735
                     /gene="galU"
                     /locus_tag="JAM15_11845"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HAT6798944.1"
                     /translation="MQMTVKKAIIPAAGLGTRFLPATKSQPKEMLPIVDKPTLQYIIE
                     EAIESGIEEILIITGRNKKSIEDHFDKSVELELELEQKGKTEMLEMVRDISNMVNIHY
                     IRQKEPKGLGHAIYCAKSFIGDEPFAVLLGDDIVDSDVPCLKQLIDTYNEYKTTVLGV
                     QKIAKEDTNKYGILDVKHIEDRVYKVKDMVEKPAIEEAPSDIAILGRYIITPAIFSIL
                     EKQTPGKGGEIQLTDALQTLGKQEAIYAYNFEGRRYDVGDKIGFLEATIDFALKRENL
                     KDDLMDYMRKKVSEK"
     gene            7760..8773
                     /gene="galE"
                     /locus_tag="JAM15_11850"
     CDS             7760..8773
                     /gene="galE"
                     /locus_tag="JAM15_11850"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HAT6798945.1"
                     /translation="MAVLVAGGAGYIGSHTAIELLESGYEVVIVDNLSNSNSIVVDRI
                     KELSKKPVKFYNIDIRNKDEMHVVFKENNIESIIHFAALKAVGESVEKPIEYYSNNLI
                     STLNLFELMREYGVKKFVFSSSATVYGDPHTCPILEDFPLSVTNPYGRTKLMIEQMLV
                     DISKADKSLDIALLRYFNPVGAHKSGRIGEEPNGVPSNLMPYITKIAVGKLKELSVYG
                     NDYPTHDGTGVRDYIHVLDLAAGHVKALQKLEENPGLVVYNLGTGKGYSVLDLVKAFS
                     KASGKEIPYKIVGRRAGDVAMCYADSSKAEKELGWKAKYELEEMCEDSWRWQSMNPNG
                     YEE"
     gene            8885..10819
                     /locus_tag="JAM15_11855"
     CDS             8885..10819
                     /locus_tag="JAM15_11855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp22"
                     /protein_id="HAT6798946.1"
                     /translation="MKKSLKKYLVLALTLVLVFACGVPESSAASKHVIIVNSRKNTLG
                     YFVNNKLVKEFRVATGKKGSETPTGKTKVVNKIKNRPYYKGNIPGGSPRNPLGDRWMG
                     LALKGTYGDTYGIHGNNNESSIGKHISGGCIRMHNKDVRWLFDQVPVGSDVIIDYSND
                     SYVKIAAKYKINLNQTGWKTENGKKYYVKSDGTYQKNSWLKVNGKMYYFDASGVMQTG
                     WKAINNKKYYLGTDGARVSGWKVIDGKTYYFNSDGVMQTGWQEKNGKKYYLGSNGLSV
                     TGWQEIDGNKYYFDKTGIMQTGWQQIDGKSYYLDKDGKMLTGSQKIDGKDYTFNEDGT
                     INPTWDTIIGANRFDTAKKISSVGNWNADSSDTVILVNGNAIADGITATPLASSYDST
                     ILLTNTANLPTETVEEMKLLAPKTVILIGGENAISSKLEQEIKTTFNTETKRIAGQDR
                     YQTATRIAEELGNREEIKTAYMVSGNGEADALSVASKAGEEKQPIILVNKDGITEESY
                     KWLTERKLENAYFIGGPSAINDSVIAKMNDITTEDISGNRIYGDSRVDTNAKVIEKFY
                     GDTDLQAVLVSKSDALVDALSAGPLAVKLHSPIVLMDNSGLSLEQQRVFANKKVETPY
                     QIGGGVSYIVMDKLMDILAK"
     gene            11028..11837
                     /locus_tag="JAM15_11860"
     CDS             11028..11837
                     /locus_tag="JAM15_11860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3800 domain-containing protein"
                     /protein_id="HAT6798947.1"
                     /translation="MFIDESGRADINHEDPFTLTGVIFEYKYAVSQGDYVCSLRKEMD
                     AFKEYCFGTSNIGIHLTDISRKSRAFEKFDDSQIKLFYDELPLFLSRLECTIISVTVD
                     KARLKKYYAPSKEPYVVAFIHVLQNFYSFVNNETVESARIVIESRDDVSNLKVQKAFF
                     DVFNNGTIYLDIDEELRDKVKGFIIAKKEDADYREGLEIADILCNPLSRARRGLIEAN
                     PKCMQYGEKNKIFKSVRNKIYTPTSVNDIRNWGFKEVPIVEPVGPWLEKMR"
     gene            complement(12045..12926)
                     /locus_tag="JAM15_11865"
     CDS             complement(12045..12926)
                     /locus_tag="JAM15_11865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAT6798948.1"
                     /translation="MNLYHLRYFVTLAHLEHYTKAAENLSITQPSLSHAISLLENELG
                     VALFEKEGRNIVLTKYGKIFLKDVEKSLEILDSSVKSLKITGTGEGQIDLAFLRTLGT
                     DFIPDIVHKFLKSNPAKSIDFKFHTGVTTDIIQGLKERKYDIAFCSKLEKEKGIEFIP
                     VAKQDLVLIVPYSHPLAAKDTIDLKETIPYPQIVFNQRSGLRYIIDDMFKKINQQPNI
                     VYEVEEDQVIAGLVAKNFGIAVVPNMNMLSFTKVKVIQIIHPSWERNFYLAFIKDRYL
                     PPAIKNFKNFVIKNAQL"
     gene            13339..14187
                     /locus_tag="JAM15_11870"
     CDS             13339..14187
                     /locus_tag="JAM15_11870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAT6798949.1"
                     /translation="MNNQKNLNIPITISSYTLGTEVSFCDRVRIAKEAGFDGIGLRAE
                     NYIDAKNAGVTDEEMIAILNEYDMKVTEVEYITQWGTEEDRTEAQREKEQNVYHMAHL
                     FNVKHINCGLLEMIPEEQIITALGELCDRAGELIIGLEFMPYSGVPDLATAWRVVKGC
                     NRENAMLILDTWHWARAKQTAEDLAPVPADKIVSIQVCDVLETPYEKLRDESLHDRLA
                     PGEGYGNTEEFVKIIKEHNISPRVIGAEVISDSLISKGLSTAAETVFNATKKVLDKAW
                     SEVSPK"
     gene            14266..16188
                     /locus_tag="JAM15_11875"
     CDS             14266..16188
                     /locus_tag="JAM15_11875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015395345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAT6798950.1"
                     /translation="MKISSMFTPIRIGSMTVPNRFVVPPMGNNFANTDGTLSETSKAY
                     YLERALGGFGLITIESSVVDKKAKGGPRKPCLYDDSTIDSFKNVIDACHDAGSKVSIQ
                     LQHAGSEGNEKVAGHPLKAASAIPASNGRNTPLAITTEEIYELIESYGDAALRAQKAG
                     ADAVEVHCAHGYLVSSFISQRTNKRVDEFGGCFENRMRLPRLIIENIRKKVGNSLAIL
                     CRINSTDDVPGGIDIHDSSVIAAYLEGCGIDGLHVSRSIHIHDEYMWAPTTLHAGFSA
                     ELVTEIKKAVSIPVITVGRYTEPQFAELMVRQGRCDLVAFGRQSLADPEMPNKAKNGK
                     LDEMIPCIACLQGCVPNMFQGKPIACLANPILGHEAELKPAEISKEVLVVGGGVGGML
                     AAWVCAKRGHNVTLVEKSEVLGGQMRLAAYPPGKGDITNLVRSYISKCNQYGVKICTN
                     TEATVELIKEKSPDVVIIATGATPLVLPIPGINDSGLIHAVDLLDGKKSCGKKVLVVG
                     GGMVGCEVAAFLGEQEHEVTVIELREEVGADVISEHRKFLMNDFENYNIHTITGAKVS
                     KFYDDGVDYLLTDGTEHDLKGFDSVVLAMGSRNYDPLSEVIKEVVKETYIVGDAVKAR
                     RALDATKEAFEVALNI"
     gene            16270..17133
                     /gene="aroE"
                     /locus_tag="JAM15_11880"
     CDS             16270..17133
                     /gene="aroE"
                     /locus_tag="JAM15_11880"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HAT6798951.1"
                     /translation="MEISGRTGLFALIGTPVGHSKSPVMYNYSFKKLDLDYRYLAFDI
                     TVDKVKEALLAIKTFNIKGANVTMPCKSAVTEYMDELSPAARIIGACNTIVNDNGKLV
                     GHITDGVGYVRNLKENGIEVKGKKITIMGAGGAATAIQVQCALDGAREISIFNAKDDF
                     YKRAEQTVENIKKDVPECVVNLYDLEDTNKLYEEIESSDILTNATLIGMKPYDNETNI
                     KDTSVLRKDLVVTDVVYNPKKTKMIEDAEANGCKAIGGLGMLLYQGAEAFNLYTGLEM
                     PVEEVNELCFK"
     gene            17333..18550
                     /locus_tag="JAM15_11885"
     CDS             17333..18550
                     /locus_tag="JAM15_11885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAT6798952.1"
                     /translation="MNNKKYYPTAIALYFSYFLLGIGISILGQYKPEFSSMWGAKTLS
                     DGTLDVSIVLAVIAALGLGRLISYPFAGPISDKYGRKVSGLIGNFLHAIFFVGIVFSP
                     NFYIAYVFAIIGGAANSFLDTCVTPSCMEIFASLGTIANMFTKFTIALAQFLLPFIIG
                     FVAANSISFKVIFIVTAILIVVDAILIAVLPFPPANNVIDNKGKTVKSEKMKFTPTSI
                     ALVCIGFTCTSTFVLWLNCNQELGKLYGMADPTKIQSFYSMGVICAVLITSLLIKKYI
                     KPIRILVIYPIIALLMLLIVYFVQTPTICMLGGFVIGYSAAGGVLQLTTSTANEMFPT
                     NKGKITSIVMIASSIANYVILNIAGIITKSGGVNGPKYVVLFNVAITFVGILLALFVN
                     MRYEKEKVYDYDV"
     gene            18786..20651
                     /locus_tag="JAM15_11890"
     CDS             18786..20651
                     /locus_tag="JAM15_11890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HAT6798953.1"
                     /translation="MENVFKRLQEFNGYDGYKESFEMNYLCIYESIPLREQVELANNL
                     VDEILNMYKSESNEIYLLEDSNSKSLICYFEIFMKKINTLVKEMIIDEKWLYKLTKEL
                     IYKSKKVEYVKLGLVLSEKYLNVENLREVVDTFSKSGEYVFYLSNTIKKLEFYNTYLF
                     NLSKKATGSIKVFAIVNMENLDSKINSYLIEDGYKDTKYERLLMNYIISIVDLNEYLE
                     KRDLDKEKINNLARLICNYLLSVEFKYIGNKLELVNRFLPTVVNYGTNFESLYSIFLI
                     AINVLKDENIEYNKIEFEKEINDILLSEKWKNIYFEALRDASGKTEDIIKMSEIYDVN
                     LSFDDLLPYLNRDIRDFEVYWHISKKGTTSSRLKLLNFFEETFKIDDLIGKMKDIEKD
                     KLTQEYYDDMLFFIVLKGSKSLYPEGKNISLKGIFGNINEVRKESINILKRYREKLSL
                     EELKIVKEAYEKEKNVILKDELRRVLYESNNLKKEFVNIEKIKVDEHGKDIYLTSIAV
                     AGSRFRNREYLEKELEKSKIYYLTREKDNLYDEKAIKIVGETGYVIGYVPRKENYILS
                     NLLDGGKLLYCRVTEYNLYEDCIYANVYLSYKDVIETVENSLKMVLDKSRIKLIN"
     gene            complement(20829..22193)
                     /locus_tag="JAM15_11895"
     CDS             complement(20829..22193)
                     /locus_tag="JAM15_11895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008699309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HAT6798954.1"
                     /translation="MSQLLIKNAYLITMNADREVYETGSILIENNIIKNVGKFDINIV
                     DKDAEIYDAKGKILMPGLVNTHVHLSQQLGRGLADDVVLLTWLRERIWPYESSFNYED
                     SLISSTACCVELIKSGVTTFLESGGQYVDAMVEAVDKTGLRACLAKSVMDTGDGLPEA
                     WQKTTDEEINTQLDLFHKFNNTSNERIKIWFALRTIFNTTEELLIRTKELADKYNTGI
                     HMHIAEIADEISFVKQNNGVGTVEYLDKLGVLGPNLLAAHTVWLTHKEIDLFRLHDVK
                     VSHNPGAAMKVVLGFASIPEMLEKGIPVSIGTDGAPSNNRMDLMRDMYLTSLIHKGRT
                     LNPTVVPAEEVLEMATINGAKCALLEKEIGSLEVGKKADMIILNPDTIHCLPMHNPIG
                     NIVYSMTSENVDSTICDGKWLMKERKVLVVDESELLNKVKKQASKIKDKAEVKIPSKF
                     KIIK"
     gene            complement(22371..23714)
                     /locus_tag="JAM15_11900"
     CDS             complement(22371..23714)
                     /locus_tag="JAM15_11900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HAT6798955.1"
                     /translation="MVPNTNNVQPDGNNSSLSFLDKMFKFSERGSSLKTEVIGGVTTF
                     LTMAYIVFVNPAILSEAGMDKAALITVTILATAIGTLIFAILGNAPFALAPGMGLNAF
                     FTYSLVIGAGIPWQTGLGVVFLSGCVFFTLAVTGLRKTIADAIPRELAVASSAGIGLF
                     LAFVGLKNMGVIIANPDTIVSLADFTPTVLIALFALILMAILEYKKVKGGILISIVVA
                     TIISVIFGFVELPTAIISTPPSIAPVAFKLDIVGALKFSLIGPIFSFMFIDMFDSLAF
                     LITCCKQMGLEDENGEIKDLGRMLYADVSSTLIGSFLGTSTVTTFGESASGIAAGART
                     GLASIVTAALFLATLIFTPLLGIVPTYAAAPALVMVGVFMFESIKQIDFADSKIAVPA
                     FVTVLLMPLTYSISIGLCFGFISYIIMHVVAKETDKISITLWIIGLLAVVNLVLS"
     regulatory      complement(23787..23888)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            24217..24870
                     /locus_tag="JAM15_11905"
     CDS             24217..24870
                     /locus_tag="JAM15_11905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HAT6798956.1"
                     /translation="MTKIIKVQKPKFTGELEIIENLEDILEDIFNDEKIFNKIIENEV
                     ISDLDSVRVSFESCIFRNVSFENCNLKKIDLLDVIFENCNLSNTFFDGGSIYRVEFKN
                     SKLIGVRFDDCILKNVLFKEVLGKYSNFSFSKFKIVSILDSNFENSVFQEVKGDNLVF
                     EYTNFKKANFNGTKLSGIDFTTNNIEGIEIGIDDIRGAIFDVSQAIDLTKLMGIIIK"
     gene            25011..26282
                     /gene="brnQ"
                     /locus_tag="JAM15_11910"
     CDS             25011..26282
                     /gene="brnQ"
                     /locus_tag="JAM15_11910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HAT6798957.1"
                     /translation="MRDIFIVGFALFSMFFGAGNLMFPPFLGMESGKDWLIPLIGFVV
                     ADAGIAMLVIIATARCKGSMDDVLRRAGKGLARVMSVAALACLALLVIPRTCATTYEM
                     GIMPIFGDHGPVAKAIFSIIFFGLTLAFTIRSSKVIDIIGKYLTPALLLVLFVLIVKG
                     IISPAGPMSPEHMIDKNLFGEGISQGYQTMDALGAASMATIMLMSIIAKGYTSDKDQI
                     GMTIKAGFVACVFLAVVYGGLTYLGATVSTLYDTSIPQASLLVEITSILLYGQVGKVI
                     LGVIVALACLTTSTGLTASISTYFEGISKASYKQLVIGICVASMLISNLGVDSIIAIS
                     VPILQTIYPVLLAIVVMELAGKHIKNDNAFKGAAYVTLVISLLSAINGMTGAVPFIQS
                     LPLAGLGFNWVIPAILGGIVGNFIKSNKQVA"
     gene            26484..27671
                     /locus_tag="JAM15_11915"
     CDS             26484..27671
                     /locus_tag="JAM15_11915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3798 domain-containing protein"
                     /protein_id="HAT6798958.1"
                     /translation="MLRKITAFMLSICLIIGLTGCSLLVGKKDKEKIIDDFKVAVVTQ
                     PLSENKVQYNMVEEMTKEYEEENKIDKDKDGQTKVKQTIKHVVLPENFTSNIDSAINK
                     IVKLADDKEVQAIVVSTDQAGLLPALQKVKEKRPEIITISAPMGDDKNQLSQFVDVNL
                     GVSAEERGKVLAERSKEMGAKAFIHYASTDDLKDVNIAKRLEMIKETCKNIGLPFVQV
                     NTPNINTEEDKNKVKQFLNEDIEKQVKKYGKDINVFGVNEYMDEVILTKALELKYIVA
                     EQSNPSPIQTYPSVMGLKISEKDAQNYDKINDMISEKAKAFGMSNRLGGYPMPMDAFL
                     PSVAIYLATEMVKQDLTQEDVCDPDYLEAFAELRFGIGSEFTPLTEVLYNYQSVILSQ
                     LIY"
BASE COUNT        10867 a         3103 c         4826 g         8941 t
ORIGIN      
        1 taacttttaa aaattagttt tactaattta caatagaata ggtgtgctgg tgtggctcaa
       61 cggtagagca gctgacttgt aatcagcagg ttgtaggttc gattcctatc accagctcca
      121 gtaaagacta tgtttttagc atagtctttt tttattgttt tttattgttt gatgtatttg
      181 ttattttgta ttacatactt ttagtggcct aatttataaa ttataagtat aaaagatgac
      241 acagtttaaa attattgttt taaactgtgt ctgtgagttt taaatcaatc taccatgaat
      301 caccattctg gcatcatcaa attcataggt acatgtagaa agtgtaacta ttttatcatt
      361 gctatttacc ttaataggag atttatacaa tgatttagaa gtaatatcat ttatgtaatt
      421 ttgataatca gattcattgt taaaatttgt ttttagataa tcataatcag attctacaat
      481 ataagcagaa aaaacatcat ataaaaattc ttttccattc aaggttattt ttattttatt
      541 attgttttta aagaagtcag catctttaaa cttatttagg ttgttgaaca tagttttatt
      601 tttcatatta tgtccatata ttatgatatt tttgtcatca atagatttat ttctataatc
      661 cataaacagt gtaccagaaa tagaatcttt tttataaaaa tctttgtcaa gatagtaaga
      721 attatcttta gattgtacaa ctggataatt tatatttgta ttctcaacag aaagccaaaa
      781 tttaaaatca ctgttaatct ttgataaatc ctctttttta tattcttttt tttgaagttc
      841 tgaggatgtt ttagtatcat gattgtattt ggtaagtttt gagtatatat taaatccact
      901 gtaaagtatt actaatacta gtataatgtt aattactatt ctatataatt ttttcaatat
      961 atcacctcga gttaaatgga gtttatatat ctatattaca ctatttttga ataaatttaa
     1021 atttttagta taatattact ttgacatgta aaagaatttg tgttaacata actaagtaaa
     1081 ataaatatta agtaagccag ataatcgcat gtaatcttac atgaggaaag tcggagctcc
     1141 atagagcagg gtgctaggta acgcctagtg ggagcgatcc taaggatagt gcaacagaaa
     1201 taaaccgccc actattgtgg taaggatgga aaggcgaggt aagagctcac cagcagctag
     1261 gcgactagtt ggctatgtaa accccacctg gagcaagacc aagataggaa taaagagtgc
     1321 tgctcgtact ctccggtagg taggtcgctt gagcctattg gtgacaatag gcctagaaag
     1381 atgattatct aatacagaac tccgcttata gacttgctta attatttcga tagtcaaaaa
     1441 catcagttta aactgatgtt tttttatttg taaatttgtc taatctactt ttaaaatttt
     1501 gaggaatatt gtaatataag ttagtacaga tattaaaaat ggtataatat aagatagata
     1561 taaaaagaaa aagtaaaatg atgtaaataa tatgatatga tataagatgt agcaaattta
     1621 gtaaataatt atttagatat cataatcaaa ttagcaactt tgcacaatgt aaatattaca
     1681 ataaaataat tgatttaagg agtgaaggtt ttgagtgaaa ataatataat aagaaacact
     1741 gttttaaatg tcacagcaag ttttttaaaa caagagtcta aaataaatga aaagctagat
     1801 ggtgttttgg aaaagaaatt tgaaaaagta gaatttaatg aagcaaaata tgcagagctt
     1861 ttaaaattta atatattgtt ttataagaca ttagcaagaa atacagaacc acttattgga
     1921 aaatggatag tagataagta catacctgaa atagatgaat tagaaaaaga tttagaatta
     1981 actacagcaa aatgtagaaa gtatgtaaat aaggctatga aagagggatt agactctcta
     2041 aaagccaatg atttaaatag ttttttagct tatgataaaa tggaactatc agagagaaga
     2101 agacgtttag aaaaggatta taaggtttta aacctatata aagaccttct taatatatct
     2161 cttagaaaaa taagtttaga aaagaaagaa tgtggagatt tatttcttaa aaatcaagca
     2221 gatgcgaaaa gagaattaaa aagagaaatt atattctgtg taaacaaaat attagctagc
     2281 aataaagatg tggtacctaa taatgtggaa gagaataacg aacaagacaa agtagaaata
     2341 aaagcaactg aaattgagga tttgcaatta ggtaaagata attcagaaaa tgacatgcta
     2401 ctaaatgaaa ttaaaaattc aaaagtaaaa catgaatcaa aatcaaatga tatagaatcg
     2461 aagtttatag ataagttaaa tagcttaaat aatgaaagta tatctcaaac aatacacaat
     2521 gaatataaga agttatgtgg attagaagaa cttcattctg ttgaaggata tggttttggc
     2581 aaagaaatta ttaaagattt tgcttgtgca acggttgtat tagaattttt aaagagaaga
     2641 aatagagacc ttatagaagg tgcaatgaga ctgactataa ttggagaatt tggtcctgaa
     2701 aattttaagg aatttgtgga ctatgtaatt aaaaataaaa cagaaattag tgaagataca
     2761 tggaataaag cacagaatct aataaaagat aactatagtg aattagaaaa tcatgaaatt
     2821 gcatcaaaaa gaactagaag aaataaagat atcgatattg aagaatacat ttacatgata
     2881 aaaaatgcag ataaagatat ttgctttaga agtagtattt caatagaaga tgatgctgaa
     2941 gaaggggcta aagaagaagt agatagtaat aatcaagata taggtgacgt tgtagaagat
     3001 aaagatacta cagataaaga gtacgacagc aataaagaag atataattga accagaaaat
     3061 aaaaagagta aaaagaaggc taaattattt ggatttatta aaaaagacaa tgaagaagtt
     3121 gaacaagaag aagagaattt aaatgatatt tctcctgata taattttaga taaaccagtt
     3181 gaaaatcatc aagcaaaatc agaagaaata gagcaaaatg aattaaaaga aataaaacaa
     3241 gaagaaccaa gtcaacatat agaagaagaa cgtagtgtaa aaatagaaaa accaataaat
     3301 aataacttag atgaaaaagt atcttcaaat aatgaatcga agcttgaaaa agaaagtaaa
     3361 aacttagaag ataaaaaagc aaaagaaata aaagaagaaa aattagaaaa tgaaaaatca
     3421 gtagtaatac ctattaaaaa gaaagaaaat agtaataaaa aatctaaaaa ttcttctaag
     3481 gacaaatata gagaaaacaa gaaagaaatg aaaaattatg tatcagataa agaagattct
     3541 ttagatgatg aagaggttgt ttctaagaag agtagattaa aagaaactat tatagcagta
     3601 gttatagtgg ttattgttgg tgtaggatat tttataacag taggcaacaa taagaaaaat
     3661 gataaagaga atattccaaa gtcatcaact caacaacaag ctaacaataa attaactgag
     3721 gaagagaaaa aagcacaagc tgaaaaagag aaaaaagaag cagaagaaaa ggcaaaagct
     3781 gaaaaagagg ctcaagaaaa agcacaagct gaaaagaaag caaaagaaat ggaagcatat
     3841 aaagatggta aaggtgtata ttacactgtt tatgcaggtt cacttaaagt tgaaaaaaca
     3901 gcaaaagaaa cagcaaaaga atatgaggct aaaggtattt cttcaacaat aattcaagaa
     3961 aatggatact ataaaataaa aataggtgat tattctcaat atggagaagc acaagaaaaa
     4021 tgtaatgaac tagctaagaa atctattgat acatatatag ctatgtatga taagtactat
     4081 gattataagt tagaagaatt aaaagaatca gctccttctt tgagtgctga agaacttaaa
     4141 caaaaatatg aagatttaag aagtgagtta aagaacaaat ctggatatcg tgaatatgtt
     4201 aaacatttag ataaacttta tgaagaaata gttgaaggtg cttagagcat tataaaaaag
     4261 gagaaactat gtctcagaat aaaaagtatt aaaaaaatat tatttgtttt gagacatttt
     4321 attcaccttt ataaaatact tataattctg tttaggtggt gaaggtatgt tgaaattagg
     4381 agaaaaaatc atatatgagc tttcagatgg gtttgagctt agtggcataa gtagatactc
     4441 aaaagaatat aaaaagcttc atataacaaa tctagggaat ataataatca gcaaatcaga
     4501 tgaagttaat gaggatacag gtgtaaaata tatatatagt ttttcagaca ataaagaaaa
     4561 attagaggca gttttagaag attctcaaat aattgtctat ggaaataact tgccttttta
     4621 cataaaaagt gaaaattcaa gtaaaaatgt tacagcaaat ttgactatga aaataacttt
     4681 ggatgaatat gatttaatct gcaaaagtca aagagaattt atattctatc taaaggataa
     4741 tatgactata ttaagtttag atgacaataa gttttatatg ggtggaatta ataaagataa
     4801 tgagaagttt atatttatca gtgggaaaaa tagatttgaa ataaattttg atgatataga
     4861 aagatacatt ttagaagata aaagagtgtc attgaaggga tactttcata tggaaagaga
     4921 ggggattata gtaaggtctg tatctatatt taataacaat atagatagtg tagttccatc
     4981 tgatttaaat gagagagtta aagataacca aaaaatagga aatcttccta aagattgtga
     5041 tatagtattc tgcaagatat caggaaatat agatggattt gattataaaa acacaaacat
     5101 gcttttagta aaatatcaag accaattaat ttttataaat aagaaatcta agaagactat
     5161 tgtaaagtca gcgaaagata attgttctaa gttaaattta ggagaagata taatattata
     5221 tgataataaa aatgtattta acctacatat aaatgataaa aatagagaaa ttatgcaaat
     5281 agatgactta aaagatatag aaaatgaaat agtgggatat acattaaaac atgctccatt
     5341 ttttattcaa gaagatttcg atagcttgac tattctaaag tcttttcaaa aagaaatcat
     5401 atctataaaa aatagtgata taaaagatat tgtaattaat aaagaacttg aaaacgaaaa
     5461 ttctaatttt gtagaaacgg aaataaaatt taataatcaa aaagtacttt taaacttaag
     5521 taaaaatatg gttcaaaaac ttatgcaaga tgtatttata tatgcaaagc aacctctact
     5581 taaagaaaat tctattgaag tgatatataa gaattggtct aaagctatga atgatatgat
     5641 aatatttaat ttctttggaa atatttacta tatgaaatct gaatttgata agattttaga
     5701 aaaagagtta aatgatgaaa taagaataga agttataaat tcactttata agcaaataca
     5761 agaacaaaga aacaatttag atttattgtc agcatatatg ccaagaatat tagaaaatca
     5821 agaaatagat ttgtttgaaa agtataatac taaacttgat gtacaagtgt ttaagcagat
     5881 taaaaatcta ttgtctgact tatcatataa tataagcagt tatttaaatg aagttgaaaa
     5941 aagtttagac aatatcatct ttgtaatttc aggagaagat aagaagaaat acaattatag
     6001 aatgttaaaa gaaagtgaaa gtgcaagtct tgatgtattt ttaaaacaag ccatatcaag
     6061 attaaaccat ttagtagaaa atatgtatcc ttattatgta gatgaaacta gtagggaaat
     6121 gtttaagtta tttgagttat tgtggaaaaa ctatagaaat attgatgatg atagtataaa
     6181 agaaatatta ttcgagagaa taacaaatac atatgtattt aaacaattga cattaaataa
     6241 tagtacaaaa gaaagaagaa aagacataat tgaaaaaata tataactctg ttgattatgg
     6301 aaccaataaa ctagatgaaa atatgttttt cacaggagga ataaagtatg tcaagtaaat
     6361 acaatgtttg gacttttaac tatgagttct taggattgga ctcaggggat gaaaaaaata
     6421 atgaagttta ttacgagatt gatttagatg aaattttaaa tgaaaactat atagatgaag
     6481 atatagatag tggtttagat tctgatggaa atagtatttt aggagaatta atatcagaaa
     6541 tggatataga tgaggatgtc agtgttgata tgacatatca agaactagaa gttgacttag
     6601 aagatttaga ttcttatcta gatgaagata tagatagtga tataaaaggc atcttagatg
     6661 aaatttagta cctgtataag ttttggataa aatataaaca atacaatatt aacttataaa
     6721 actaaaggta gatgaaattt catctacctt atattatctt atagcattaa atattgggat
     6781 aatatagagt ttgaagaaaa agtataaata tggtatatta atttggtaca atagaaaatt
     6841 tacgaagaag ggtgaaaaaa tgcagatgac agttaaaaaa gcaataatac cagcagcagg
     6901 gctaggaact agatttttac cagcaacaaa atcacagccc aaagaaatgc ttcctatagt
     6961 agataaacca actttacagt atataataga agaagctata gaatcgggaa ttgaagaaat
     7021 tcttataata acaggtagaa ataaaaaatc tatagaagat cattttgata aatcagttga
     7081 attagagtta gaactagagc aaaaaggtaa gacagagatg ttagaaatgg taagagacat
     7141 atcaaatatg gtaaatattc attatataag acaaaaagag ccaaaaggtc ttggacatgc
     7201 aatttactgt gcaaaaagtt ttataggtga tgaacctttt gccgtattat taggtgatga
     7261 tatagtagat tcagatgttc cgtgcttaaa acaattaata gatacttata atgagtataa
     7321 aacaactgta ttaggtgttc aaaagatagc taaagaagat actaataaat atggtatatt
     7381 ggatgtaaaa catatcgaag atagagtata taaagttaaa gatatggttg aaaaacctgc
     7441 aattgaagaa gctccatctg atatagctat acttggaaga tatataataa ctcctgcaat
     7501 atttagtata ttagagaaac agacacctgg taaaggtgga gagatacaac tgacagatgc
     7561 acttcaaact cttggaaaac aagaggctat ttatgcttat aactttgaag gtagaagata
     7621 tgatgtggga gataagattg gttttttaga ggcaacaata gactttgctc taaagagaga
     7681 aaatttaaaa gatgatttaa tggactatat gagaaaaaaa gtaagtgaaa aataaaatat
     7741 tagaaaagag gtaattacaa tggcagtttt agtagctgga ggagcaggat atataggaag
     7801 ccatacagca atagaacttt tagaatcagg ttatgaagtt gttatagttg ataacttaag
     7861 taatagcaac tcaatagtgg ttgatagaat taaggaatta tctaaaaaac cagtaaaatt
     7921 ttataatatt gatatcagaa ataaagatga aatgcatgtt gtatttaaag aaaataatat
     7981 tgaatcaatt atacactttg cagctttaaa agcagttggt gaatcagtag aaaaaccaat
     8041 tgaatattac agcaataatc taataagtac cttaaattta tttgaattaa tgagagaata
     8101 tggtgttaaa aagtttgtat ttagttcttc agctactgta tatggagacc cacatacttg
     8161 tcctatatta gaggatttcc cactttctgt aaccaatcca tatggaagaa ctaaacttat
     8221 gatagagcag atgttagtag atatatcaaa agcagataag tcattggata tagctctttt
     8281 aagatacttt aatccagttg gtgctcataa aagtggtaga ataggtgaag aaccaaatgg
     8341 agttccgagc aatctaatgc cttatataac aaaaatagca gtaggtaaat tgaaggaatt
     8401 gagtgtttat ggtaatgatt atccaacaca tgatggaact ggagttagag actatataca
     8461 tgtattagat ttagctgctg gtcatgtaaa agcattacaa aaattagaag aaaatccagg
     8521 acttgttgtt tataatttag gaactggaaa ggggtatagt gttcttgatt tagtaaaagc
     8581 attttctaaa gcaagtggaa aagaaatacc atataagatt gtaggaagaa gggctggaga
     8641 tgtagccatg tgttatgcag attcttcaaa ggcagaaaaa gagcttggat ggaaagctaa
     8701 gtatgaactt gaagagatgt gtgaagattc atggagatgg caaagtatga atcctaatgg
     8761 gtatgaagag tagaatacat acttatatgt ataaatgtaa caaatttgta aatataaggt
     8821 attggtaatt ttatgttata attagacaca tgtagtaatg tttctaaaag agggggaagt
     8881 tatagtgaaa aaaagtctaa aaaagtattt agtactagca ctgactttag ttttagtatt
     8941 tgcatgtggc gtaccagaat caagcgcagc cagtaaacat gtgattatag taaattcaag
     9001 aaagaatact ctaggatatt ttgtaaataa taaacttgta aaagaattta gagttgcaac
     9061 aggtaaaaag gggtcagaaa caccaacagg gaaaacaaaa gtagttaaca agataaaaaa
     9121 tagaccatat tataaaggta atatacctgg aggaagtcca agaaatccat taggagatag
     9181 atggatggga ttagcattaa aaggaactta tggagataca tatggaatac atggaaataa
     9241 taatgagagt tctataggaa agcatatttc tggtggctgt ataagaatgc acaataaaga
     9301 tgttagatgg ttatttgacc aagttcctgt aggttcagat gtaattatag attatagtaa
     9361 tgacagctat gtaaagatag cggcaaaata taagataaat ctaaatcaaa caggatggaa
     9421 aacagaaaat ggtaagaagt attatgtaaa atctgatgga acataccaaa agaatagttg
     9481 gctaaaagta aatggaaaaa tgtattactt tgatgcttca ggagtaatgc aaacaggatg
     9541 gaaagcaatt aataacaaaa aatattattt aggaactgat ggagcaagag tatctggatg
     9601 gaaagtaata gacggaaaaa cttattactt taactcagat ggagtaatgc aaacaggatg
     9661 gcaagaaaag aatggaaaga aatactatct aggatctaat ggtttatcag taacaggatg
     9721 gcaagaaata gatggtaata agtattactt tgataaaaca ggaataatgc agacaggatg
     9781 gcaacaaata gatggtaagt cttactattt agacaaagat ggaaagatgc taactggttc
     9841 tcaaaaaata gatgggaaag attatacttt taatgaagat ggaactataa atcctacatg
     9901 ggatacaatt ataggtgcaa atagatttga tacagctaaa aagataagtt cagttggaaa
     9961 ctggaatgct gatagttcag atactgtaat attagtaaat ggtaatgcaa tagctgatgg
    10021 tataacagca actcctttag caagtagcta tgactcaaca atactactta ctaatacagc
    10081 taatttacca actgaaactg ttgaagaaat gaagttatta gcacctaaaa cagtaatctt
    10141 gataggtgga gaaaatgcaa taagttctaa attagagcaa gaaataaaaa ctactttcaa
    10201 cacagagaca aagagaatag caggtcaaga tagatatcaa actgctacaa gaatagctga
    10261 agaacttgga aatcgagaag aaataaaaac tgcatatatg gtttctggaa atggggaagc
    10321 agatgcttta tctgtagctt ctaaagctgg ggaagaaaaa caacctataa tattagtcaa
    10381 taaagatgga attacagaag aatcttataa atggctaaca gaaagaaaat tagaaaatgc
    10441 atactttata ggtggaccaa gtgcaattaa cgattcagta atagcaaaaa tgaatgatat
    10501 aactactgaa gatatttcag gaaatagaat atatggagat agtagagtag atactaatgc
    10561 caaagtaata gaaaaattct atggagatac tgatttacag gctgtattag ttagtaaatc
    10621 agatgcttta gtagatgctt tatcagctgg accattagct gtaaaattac attcaccaat
    10681 agttttaatg gataattcag gattatcatt agaacaacaa agagtatttg caaataaaaa
    10741 agttgaaact ccttatcaaa taggaggcgg agtatcttat atagtaatgg ataaattaat
    10801 ggatattctt gcaaaatagt aaaaatatat attgaaaaat aattataatt gagatgtgaa
    10861 attcaatcaa taaaagcttg attgttttac atctcaattt tttagtataa aattaagttt
    10921 aagttatata aaaatcttgg aatattttta aaactcatat aaaatgaata tagatgctat
    10981 catcatatgt taagagggtg agtaagatta taaagaaaaa atatataatg tttattgatg
    11041 aaagtggaag agctgatata aatcatgaag acccatttac attgacagga gtaatttttg
    11101 aatataaata tgcagtaagt caaggcgatt atgtatgttc tttgaggaaa gaaatggatg
    11161 catttaaaga gtattgtttt ggaaccagta acataggaat acatttgaca gatatatcaa
    11221 gaaaatcaag agcatttgag aagtttgatg attcacagat taagttattc tatgatgagt
    11281 tgcctttatt tctatctaga ttagagtgta ctataatatc agtaacagta gataaagcta
    11341 gattaaagaa atattatgca ccttcaaagg aaccgtatgt tgtggctttt atacatgttc
    11401 ttcagaattt ttattcattt gtaaataatg aaactgtaga atctgcacga atagttatag
    11461 agtcaaggga tgatgtctca aacttaaaag tacaaaaggc gttttttgat gtatttaata
    11521 atggaacaat atacttagat atagatgaag aattaagaga taaggttaag ggttttataa
    11581 ttgccaaaaa agaagatgct gactatagag aaggtttaga aatagcagat attttatgta
    11641 atcctcttag cagagcaaga agagggttaa tagaagctaa tccaaagtgt atgcaatatg
    11701 gagaaaaaaa caaaatattc aaatctgtca gaaacaaaat atatactcca acgagtgtga
    11761 atgatataag aaattgggga tttaaagaag ttcctattgt agagcctgtt ggaccatggc
    11821 ttgaaaaaat gcgttagata caattgacaa attttaaaaa atctgatata atgtaaataa
    11881 cctagttatt caggaactga atccagttgc tgttgtataa cgataattac tgagactcgg
    11941 atgccgactg tcagttagga atctatactt ttaaaagtat agattttttt attttataaa
    12001 aagaataaaa gaggatattt aaaaataacc cctttattaa taaattataa ttgagcgttt
    12061 ttaatgacaa agtttttaaa gtttttaatt gcaggaggca aatatctatc ttttataaat
    12121 gctaagtaaa agtttctttc ccaacttggg tgaataatct gaattacttt tacttttgta
    12181 aagctaagca tattcatatt tgggactaca gcaattccga aattttttgc aactaatcca
    12241 gcaattactt ggtcttcctc tacttcatag actatattag gctgttgatt tattttttta
    12301 aacatatcat caattatata tctaagacca cttctctgat taaatactat ttgaggataa
    12361 ggtatggttt cttttaaatc tatagtatcc tttgcagcta gtggatgact atatggtaca
    12421 attagtacta aatcttgttt ggcaacaggt ataaattcaa ttcccttttc tttttcaagt
    12481 ttcgaacaaa atgcaatatc atattttctt tctttaagac cttgaataat gtcagtagtt
    12541 acaccagtat gaaatttaaa atctattgat ttagcaggat tagattttaa aaatttatgc
    12601 actatgtctg ggataaaatc agtaccaagt gttctaagaa aagctaagtc tatttgtcct
    12661 tcaccagtac cagttatttt taatgatttt acacttgaat ctaaaatttc taatgatttt
    12721 tccacatctt ttaaaaatat ttttccatac ttagtaagga ctatatttct accttctttt
    12781 tcaaatagag ccaccccaag ttcattttct agtaaagaaa tagcatgact taagcttggt
    12841 tgtgttatag ataaattttc tgccgctttt gtatagtgtt ctaaatgtgc caatgtaaca
    12901 aaatagcgta agtgatataa attcaatttt tgttcatcct ttcataggta tttttattta
    12961 tatatttgta gaagttaacc tttaagatat ttttacattt ttattatata tgattataga
    13021 gtaagaataa aagcttttaa aaaaatttat cgttttttgt ctgaattata agataaatat
    13081 atttatacaa cctaatagaa aaatacaaga attatcttat aaataaaatc tataaacaaa
    13141 atctatgaat taataggaaa ttatcaattt gttattagta aagtctcgtg atacaataaa
    13201 tttataaaat ctagataaat agaaatcaaa aaatactttt atttttaagg taaaataata
    13261 ctactagtag gataaataaa aatataaaat caaagatact attaattata aagaaaataa
    13321 agggggcaaa tttaagctat gaataatcaa aaaaatctta atattccaat tacaattagt
    13381 tcttatacat tgggaacaga agtttcattc tgtgatagag ttcgtattgc aaaagaagct
    13441 ggatttgatg gtattggatt gcgtgctgaa aattatattg atgcaaaaaa tgcaggtgtt
    13501 acagatgaag aaatgattgc aattcttaat gaatatgata tgaaagttac agaagtagaa
    13561 tatataactc aatggggaac agaagaagat agaacggaag ctcaaagaga aaaagagcaa
    13621 aatgtttatc atatggctca cttatttaat gttaaacata taaattgtgg attattagag
    13681 atgataccag aagaacaaat tataactgca ttgggagaat tatgtgacag agcaggtgaa
    13741 cttattatag gtcttgagtt tatgccatat agtggtgtac cagatttggc tactgcatgg
    13801 cgtgttgtga aaggatgtaa tcgtgaaaat gcaatgctta tattagatac ttggcactgg
    13861 gctagagcaa agcagacagc agaggacctt gcacctgttc cagcagataa gatagtatca
    13921 attcaagtgt gtgatgtttt agaaactcct tatgaaaaac ttagggatga atcactacat
    13981 gaccgtttgg ctccaggtga aggatatgga aacacagagg aatttgtgaa aataataaaa
    14041 gaacacaata tatcaccaag agtcataggg gcagaagtaa tatctgattc tctaatatct
    14101 aaagggttat ccactgctgc tgaaactgta tttaatgcaa ctaaaaaagt tttggataaa
    14161 gcatggtctg aagtatctcc aaaataaact tatataatat aaaaatatac agagtattat
    14221 aatataaaac ttttaaatat aaaacttgaa aggaaggaaa accttatgaa gattagttct
    14281 atgtttacac ctataagaat tggttcaatg acagttccaa atcgttttgt agttccccct
    14341 atgggaaaca attttgcaaa cacagacggt actttaagtg aaacttctaa ggcttattat
    14401 cttgagcgtg ctttaggtgg ttttggatta ataactatag aatctagtgt tgtagacaaa
    14461 aaagcaaaag gaggtcctcg taagccttgt ttatatgatg atagcacaat agatagtttt
    14521 aaaaatgtaa tagatgcttg tcatgatgca ggttcgaagg tatctataca attacaacat
    14581 gctggttctg aaggaaatga aaaagtagca ggacatccat taaaagctgc ttctgcaata
    14641 cctgcatcaa atggtcgtaa tacaccacta gcaataacaa cagaagaaat atatgaactt
    14701 atagaatctt atggagatgc tgcattacgt gcacaaaaag ctggtgcaga tgctgttgaa
    14761 gttcactgcg ctcatggata tctggttagt agttttatat cacaaagaac aaataagcgt
    14821 gtagatgagt ttggtggatg ttttgaaaat agaatgagat tacctcgtct tatcattgaa
    14881 aatatacgta aaaaagtagg aaattctcta gcaatattat gtcgtataaa cagcactgat
    14941 gatgttccag gaggaattga tatacatgat agttcagtaa tagcagcata tctagaaggt
    15001 tgtggaatag atggacttca tgtttcacgt agtatacata tacatgatga atatatgtgg
    15061 gctcctacga ctttacatgc tggattcagt gcagaattag ttactgaaat aaaaaaagct
    15121 gttagtatac cagtaataac agttggacgt tatacagagc cacagtttgc tgagttaatg
    15181 gtcagacaag gaagatgtga tttagtagca ttcggtagac aaagcttggc tgacccagaa
    15241 atgcctaata aagctaaaaa tggaaaacta gacgaaatga taccatgtat tgcatgctta
    15301 caaggatgtg taccaaatat gttccaagga aaacctatag cctgtcttgc aaatcctata
    15361 ttaggacatg aagcagagct taagccagct gaaattagca aagaagttct tgttgttggt
    15421 ggaggtgttg gaggtatgct tgcagcatgg gtatgtgcta aaagaggaca taatgtaact
    15481 ttagttgaaa aatctgaagt tcttggtggg caaatgcgtt tagctgcata tcctccagga
    15541 aaaggagata ttactaactt agttagaagt tatatttcaa aatgtaatca atatggtgta
    15601 aaaatatgta ctaatacaga agctacagta gaacttataa aagagaaatc acctgatgta
    15661 gttattatag ctactggagc aactccactt gtacttccta taccaggaat caatgattca
    15721 ggattaattc atgctgtaga ccttcttgat ggtaaaaaat cttgtgggaa aaaagtactt
    15781 gttgttggag gtggaatggt tggatgtgaa gtggcagcct tccttggaga acaagaacat
    15841 gaggttactg ttattgagct tagagaagaa gttggtgcag atgtaatttc agagcaccgt
    15901 aaattcctta tgaatgattt tgaaaattat aatatacata ccattactgg tgcaaaagtt
    15961 tctaaatttt atgatgatgg tgtcgactat ttacttacag atggcacaga gcatgattta
    16021 aaaggttttg attcagtagt acttgctatg ggttctcgta attacgaccc attaagtgaa
    16081 gttataaaag aagttgtaaa agaaacttat attgttggtg atgcagtaaa agctcgtagg
    16141 gcattagatg caacaaaaga agcttttgaa gtagcattaa atatataaat aataaataaa
    16201 tttttctttg taaataactg aataggttat ttgcaaagaa aatgataata ttgggaggaa
    16261 attatagtta tggaaatttc aggtagaaca ggattatttg cattaatagg tacaccagtt
    16321 ggtcactcta aatcaccagt gatgtataat tatagtttta agaaattaga tttagattat
    16381 agatatttag cctttgatat cacagtagat aaggtaaaag aggcactttt agcaataaaa
    16441 acttttaata taaaaggagc caatgttact atgccatgta aatctgctgt tacagaatat
    16501 atggatgaac tttctccagc agctcgtata attggagcat gtaatacaat tgtaaatgac
    16561 aatggaaagt tagttggtca tataacagat ggagtaggct atgttcgtaa tttaaaagaa
    16621 aatgggatag aagttaaagg taaaaagatt acaattatgg gtgctggtgg tgcagcaact
    16681 gctatacaag tacaatgtgc tttagatgga gcaagagaaa tatctatctt taatgctaag
    16741 gatgattttt ataaaagagc agagcagaca gttgagaata taaaaaaaga tgtaccagaa
    16801 tgtgttgtta atctatatga tttagaagat acaaacaaac tttatgagga gatagaatca
    16861 agtgatatat tgacaaatgc aactcttatt ggtatgaagc cttatgacaa tgaaacaaat
    16921 ataaaagata ctagtgtttt aagaaaagac ttagtagtaa cagatgtcgt ttataatcct
    16981 aagaaaacaa aaatgattga agatgctgaa gctaatggat gtaaggctat tggtggatta
    17041 ggaatgttat tataccaagg agcagaagct tttaatctat atactggatt agaaatgcct
    17101 gtagaagaag ttaatgaatt atgctttaaa tagataagag tgatatctta aacaatgaaa
    17161 aaacatacgt atttcaatat ttttaataat aaattacaaa ttgtcatagt gggttttgca
    17221 tcatagtcca gttaaatttg aagctttaac tgactatact ttaaatccat tatgaggatg
    17281 agtttattgt acacaaaaat gttaataaat taacaagaat gggagaaaaa ttatgaacaa
    17341 taaaaaatat tatcctactg ccatagcgtt gtatttttca tattttttac ttggtattgg
    17401 aatttcaatt ttaggacaat acaaaccaga attttcatca atgtgggggg ctaaaacact
    17461 atcagatgga acattggatg taagtattgt tttagctgtt attgctgcac taggattagg
    17521 gagacttata tcttatccat ttgcaggacc tatttcagat aagtatggaa gaaaagtaag
    17581 tggtcttata ggaaactttc tacatgcaat tttctttgtt ggaattgtat tttcaccaaa
    17641 tttttatata gcatatgtat ttgcaataat tggaggggca gcaaattcat tcttagatac
    17701 ctgtgtaact ccttcttgta tggagatatt tgctagttta ggaacaatag caaatatgtt
    17761 tactaaattt acaatagctt tagcacaatt tttgcttcct tttataattg gatttgttgc
    17821 agcaaattca atatcattta aagttatttt tatagtaaca gcgattctta ttgtagtaga
    17881 tgccattttg atagctgtgt taccatttcc accagctaat aatgttattg ataacaaagg
    17941 caaaacagtt aaatcagaga agatgaaatt tacaccaaca agtatagctc ttgtttgtat
    18001 tggatttaca tgtacatcta catttgtatt atggttaaat tgtaatcagg aattgggtaa
    18061 attgtatggg atggctgacc ctacaaaaat tcaatccttt tactcaatgg gagtaatatg
    18121 tgcagtatta ataacttctt tacttattaa aaaatatatt aaaccaataa gaatattagt
    18181 tatatatcct ataatagctt tacttatgct attaattgta tattttgttc aaactccaac
    18241 tatttgtatg ttagggggat ttgtaatagg ttattcagca gcaggaggtg ttcttcagtt
    18301 aacaacgtca actgcaaatg aaatgtttcc aactaataaa ggaaaaataa catctatagt
    18361 tatgattgca tctagtatag caaactatgt tattttaaat atagcaggta ttattacaaa
    18421 atcaggggga gttaatggac caaaatatgt tgtattgttt aatgtggcaa taacatttgt
    18481 tggaatttta cttgcattgt ttgtaaacat gagatatgaa aaagaaaaag tgtatgatta
    18541 tgatgtctaa tattagtata atatatgcat agagaagtct aaatctagga tagattttta
    18601 ttaaaagtaa ttaaaattaa taaggatatt atttacagtt ataagatagg gtatttacat
    18661 aattaataat aaggatatta ctagaatttc aatttctagt aatatttttt tgcgtataaa
    18721 tgtaaacttg acgaaataag tagtataatc aatataaatt acatcatgta aaggaggata
    18781 atttggtgga gaatgttttt aagcgattgc aggaatttaa tggttatgat ggatacaaag
    18841 aatcatttga aatgaattac ctatgtatat atgaaagtat accgttaaga gaacaagtag
    18901 aacttgcaaa taatctagta gatgaaattt taaatatgta taaaagtgaa tctaatgaaa
    18961 tttatttatt ggaggatagt aattctaagt ctttaatttg ttatttcgaa atttttatga
    19021 aaaagataaa tactttggta aaagaaatga ttattgatga gaaatggtta tataaattaa
    19081 ctaaagaatt aatatataag agtaaaaaag ttgagtatgt aaaactaggg ttagttttaa
    19141 gtgagaaata tctaaatgta gaaaacttaa gagaagttgt agatacattt tctaaatctg
    19201 gagaatacgt attttatctg agtaatacta ttaaaaaact tgaattttac aatacatatt
    19261 tatttaattt atctaaaaag gctacaggtt caataaaagt atttgctatt gttaatatgg
    19321 aaaatttaga ttctaaaata aattcctatc taattgaaga tggttataag gatacaaagt
    19381 acgaacgatt attgatgaac tatattattt caattgtaga tttgaatgaa tatcttgaaa
    19441 aacgagattt agataaagaa aagataaata atttagcacg tcttatatgc aattacttgc
    19501 taagtgtaga atttaaatat ataggtaata aattagaatt agtgaatcga tttttaccta
    19561 ctgtagtaaa ttatgggact aactttgaaa gtttatattc aattttccta atagctataa
    19621 acgtcttaaa agatgaaaat atagagtaca ataagattga atttgaaaaa gaaataaatg
    19681 atatcttgct cagtgaaaaa tggaaaaata tatattttga agcattaaga gatgctagtg
    19741 gaaaaacaga agatattata aaaatgtcag aaatttatga tgtaaactta tcttttgatg
    19801 acttgttgcc atatctgaat agagatatta gagattttga ggtatattgg catatatcta
    19861 aaaagggaac gacaagttct agattaaaat tattaaattt ttttgaagag acgtttaaaa
    19921 tagatgattt aattggaaaa atgaaagata tagaaaaaga taaattgact caagaatatt
    19981 atgatgatat gttatttttt attgtgctta aaggaagtaa atcactatat cctgaaggaa
    20041 agaatatatc tttaaaagga atatttggaa atataaatga agtaagaaaa gaatccataa
    20101 atatcttaaa aagatacaga gagaaactat ctcttgaaga attaaaaatt gttaaagaag
    20161 cgtatgaaaa agaaaaaaat gttatattga aggatgaatt aagaagagta ttatatgaaa
    20221 gtaataattt aaaaaaagaa tttgtaaata ttgaaaaaat aaaagtagat gaacatggta
    20281 aggatatcta tttgacttca atagctgttg ctggttcaag gtttagaaat agagaatatc
    20341 ttgaaaaaga attggagaag agtaagatat actatttaac tagagagaaa gataatctat
    20401 atgatgaaaa agctattaaa atagttggtg aaactggata tgtaataggc tatgtcccaa
    20461 gaaaagaaaa ctatattttg agcaatttat tagatggagg aaaactgctg tattgtagag
    20521 taactgaata taatttatat gaagattgta tctacgcaaa tgtgtacttg agttataaag
    20581 atgtaattga aacagttgaa aactctttaa agatggtttt agataagagt agaataaaac
    20641 ttataaacta agacgtttat atattgctta gatgatgtaa tcctaactga ttggttattt
    20701 tttctggaat tatggtgtat tttatgagca atgctaatga atataaaata aaaaaacaat
    20761 tgttttgtat atatgatgtg tataaatata tttatatatt catatttaca aaacaattga
    20821 aatttatgtt attttatgat tttaaattta gatggaattt taacttctgc tttatctttt
    20881 attttagaag cttgtttttt aactttattt aataattcag attcatctac aactaatact
    20941 tttctttcct tcatcaacca tttaccatca caaatagtag aatctacatt ttcactagtc
    21001 atagaataaa ctatatttcc aattggatta tgcattggta aacaatgaat tgtatctgga
    21061 tttagaataa tcatatcagc tttttttcct acttcaagac taccaatttc tttttctagt
    21121 aaagcacatt ttgctccatt tatagtagcc atttctaaga cttcttcagc tggtacgaca
    21181 gttgggttta aagttctacc tttatgtatt agtgatgtaa gatacatatc cctcataagg
    21241 tccattctat tatttgaagg agctccatca gtaccaattg aaacaggtat tcctttttct
    21301 aacatttcag gaattgaggc aaatcctaga actactttca tagctgcacc tggattatga
    21361 gaaactttta catcatgtaa tctaaataaa tcaatttctt tatgagtaag ccaaactgtg
    21421 tgagcagcta aaagatttgg tcctaataca cctagtttat caagatattc aactgttcca
    21481 actccgttgt tttgctttac aaatgaaatt tcatcagcta tttcagcaat atgcatatgt
    21541 atacctgtat tgtatttatc agctaactct ttagtcctaa taagcaattc ttcagttgta
    21601 ttaaaaatag ttcttaatgc aaaccatatt ttaatcctct cattagatgt gttattaaac
    21661 ttatggaata agtctaattg agtgttgatt tcctcatcag tagttttttg ccatgcttca
    21721 ggaagaccat ctcctgtatc cataactgat ttagctaaac aggctctaag tccagtttta
    21781 tcaacagctt caaccatagc atctacatat tgaccaccag attctaaaaa tgtagttacc
    21841 ccagatttta tcaattcaac acaacatgca gtagatgaaa tcaatgaatc ttcatagttg
    21901 aagctacttt cgtatggcca gattctctct ctaagccaag ttaaaagtac aacatcatct
    21961 gcaagaccac gtcctaattg ttgggataag tgaacgtgtg tattgactaa ccctggcatt
    22021 agtatttttc ctttagcatc atatatctca gcatctttat ctacaatatt aatatcaaac
    22081 ttaccaacat tttttataat attattttca ataagtatac ttccagtttc atatacctct
    22141 ctatctgcat tcatagtaat tagatatgca ttttttataa gtaattgtga cataagtaca
    22201 acctcttttc tatatatttt tatatctatg tattatgata ataaattttc tatacaaagt
    22261 taatagcaaa atcaatttat acataaattg attttgctat ttataaattt aaaataaata
    22321 agattttatt ttatataatt taaaatattg acctagaact atttaaaata ttaacttaga
    22381 actaagttta caactgcaag taaacctata atccaaagtg taatactgat tttatcagtt
    22441 tctttagcta ccacatgcat tattatatat gaaataaatc caaagcataa accaatactt
    22501 atactataag ttaaaggcat caataaaact gtaacaaaag caggtactgc tattttgcta
    22561 tcagcaaaat caatctgttt tatgctttca aacatgaata caccaaccat tacaagtgca
    22621 ggagctgcag cgtaagtagg aactatacca agtaatggtg taaatataag tgtagctaag
    22681 aataatgctg ctgttactat tgaagcaagt cctgttcttg cacctgctgc aataccagaa
    22741 gcagattctc caaatgttgt aacagtacta gttcctaaga atgagcctat taaagtagaa
    22801 gaaacatctg catataacat tcttcctaaa tcttttattt caccattctc atcttcaaga
    22861 cccatttgtt tacaacaagt aataagaaat gctaatgaat caaacatgtc tataaacatg
    22921 aaagagaata taggtccaat taatgagaat ttcaatgcac ctacaatatc taatttaaaa
    22981 gcaactggtg ctatactagg aggtgttgag attattgctg ttggcaactc cacaaatcca
    23041 aatataacag atattattgt tgcaactact atacttatca atattccacc tttaactttt
    23101 ttatattcta gtattgccat taagataaga gcaaaaagag ctattaaaac tgttggtgta
    23161 aaatctgcaa gtgaaactat agtatctgga ttagctatta taacacccat attttttaaa
    23221 ccaacaaaag caaggaaaag acctatacct gctgaagatg ctactgccaa ttctctagga
    23281 attgcgtctg caattgtctt tcgaagacct gttactgcga gtgtaaagaa gacacatcca
    23341 gatagaaaaa ctaccccaag acctgtttgc catgggattc ctgcacctat aaccaaagag
    23401 tatgtgaaaa atgcatttaa tcccatacca ggagctagag caaatggtgc atttcctaaa
    23461 atcgcaaata taagtgtacc aatggctgta gctagtatgg taactgttat aagggcggct
    23521 ttatccattc cagcttcaga taatattgct ggatttacga aaactatgta tgccattgtt
    23581 aagaatgtag taactccacc tattacttct gttttaaggc tagagccacg ttcgctaaat
    23641 ttaaacattt tgtctaaaaa gcttaatgat gaattatttc catctggttg tacattgtta
    23701 gtgtttggta ccatttttac ctccaaaaaa ctttaagata taaacaaaaa aatatatatt
    23761 catatagata gaatagaaca tatattcaga gttgacattc tattcataga aaacccattt
    23821 aaggtgagtt tgtagaaact attagaccgt attactaata ttatatgaac attttctatt
    23881 tgtttttctg ttgtattata tcgtaatatt gtattattta caataaatat aataaaatta
    23941 ttcgtttttt tgtcgatttt ataaaaaatt aaggttattt attggcaaga attactgttt
    24001 tcaataattg aatatgtata agtataatgt caattattct aacttgtttt atactattaa
    24061 tagaagtcta ttataaatga gtttgtgata taattataaa agtactgaat acacggatat
    24121 ttcgtaaaaa ctttttaata tatcaaatat gtatattaag ttaatatatt aaaaaaaata
    24181 atatcaaaaa taatataatt tatagtggag gggaaaatga ctaaaattat taaagtgcaa
    24241 aaacctaaat ttacaggaga attagaaatt attgaaaatc ttgaagatat acttgaagat
    24301 atatttaatg atgaaaaaat atttaataaa attatagaaa atgaagttat aagtgattta
    24361 gattctgtaa gagttagctt tgaatcttgt atatttagaa atgtgtcctt tgaaaattgt
    24421 aatttaaaaa agattgattt acttgatgtg atatttgaaa actgcaattt atcaaataca
    24481 ttttttgatg gaggaagtat atacagagtt gaatttaaaa atagtaaatt gataggagtt
    24541 agatttgatg attgtatact taaaaacgtt ttgttcaagg aggttttagg taagtattct
    24601 aacttttcat tctctaaatt taagatagtt tctatcttag attcaaattt tgaaaattct
    24661 gtatttcaag aagtaaaagg tgacaatcta gtatttgagt atacaaattt taaaaaagca
    24721 aactttaatg gaactaaact ttctggcata gattttacta ctaataatat tgagggaatt
    24781 gagattggta tagatgatat tagaggagca atttttgatg tgtcacaagc aattgattta
    24841 acgaaattga tgggaattat cataaaatga aaaaaatatt cataaaataa attgggaaaa
    24901 cgttaacaat atgtggattt ttaccagatt gacatttttc tgaaaataaa gtaagattat
    24961 cttaatattc aaaatatttt caaagggggt aatttagtgt gagtaagcag atgagagata
    25021 tttttatagt tggttttgct ttattttcta tgttctttgg tgcaggaaat cttatgtttc
    25081 ctccattttt agggatggaa tccggcaaag actggttaat tcctcttatt ggatttgttg
    25141 ttgcagatgc tggtatagca atgcttgtta ttatagcaac agcaagatgc aagggaagca
    25201 tggatgatgt acttaggaga gctggtaaag ggttagcaag agtaatgagt gtagctgctc
    25261 tagcatgttt agcacttctt gtaataccaa gaacttgtgc aacaacatat gaaatgggta
    25321 ttatgcctat atttggagac catggaccag tagctaaagc tatattttca ataatcttct
    25381 ttgggttaac tttagcattt actattaggt cttctaaggt tatagacata ataggtaagt
    25441 atttaactcc agcgttatta ttagtattat ttgttttaat agtaaagggt ataatttctc
    25501 cagcaggacc tatgagtcct gagcatatga tagataaaaa tctatttggt gaaggtatat
    25561 cacaaggtta tcaaacaatg gacgctctag gtgcagcatc tatggcaact ataatgttga
    25621 tgtctataat agctaaagga tatacatcag ataaagacca aataggaatg actattaaag
    25681 ctggttttgt agcctgtgta tttctagcag tagtatatgg tggtcttact tatttaggtg
    25741 caacagtttc aactttatat gatactagta tacctcaagc atctttatta gttgaaataa
    25801 ctagtatatt gttatatggt caagtaggaa aggtaatttt aggtgtaatt gtggcacttg
    25861 cctgtctgac tacttctaca ggtttaacag catcaatatc aacttatttt gaaggaataa
    25921 gtaaggcgag ttacaaacaa ctggttatag gtatatgtgt agctagtatg cttatatcaa
    25981 atttaggtgt tgattctata atagctatat cagttccaat cctacaaact atatatcctg
    26041 ttttattagc aatagttgtt atggagttgg ctggtaaaca tataaagaat gataatgctt
    26101 ttaaaggtgc agcatatgtt acattagtga ttagtctatt atcagctata aatggaatga
    26161 caggagctgt tccatttata caaagcttgc cactcgcagg tttgggcttt aactgggtaa
    26221 taccagctat attgggtgga atagttggta actttataaa aagcaacaaa caagtagcat
    26281 aataatttgt aattaattta attttataat atattaattt ttagtactat gggtaggttt
    26341 aatctaaacc taatctaccc atagtacttt ttagattgga ttggaatagc atgtatataa
    26401 ttttttataa tataattttt ctttgaagta tgataaaatt agtaatagtg ataagaaagt
    26461 acaaatttag gaggttttaa ttaatgctta gaaaaataac agcatttatg ctatccatat
    26521 gtttaattat tggacttaca ggttgtagtt tacttgtagg caagaaagat aaagagaaaa
    26581 ttatagatga ttttaaagtt gcagtggtaa ctcaaccatt atctgaaaat aaagtacaat
    26641 acaatatggt ggaagagatg acaaaagaat atgaggaaga gaataaaatt gataaagaca
    26701 aagatggtca aactaaagtt aaacaaacta taaaacatgt tgtattgcca gagaatttta
    26761 cttctaatat agatagtgct attaataaga tagtaaagtt ggctgacgat aaagaagttc
    26821 aggctattgt agtttcaact gaccaagcag ggcttttacc tgctttacaa aaggtaaagg
    26881 aaaagcgtcc agaaataata actatttctg cccccatggg agatgataaa aaccaattaa
    26941 gccaatttgt tgatgtgaat ctaggggtta gtgcagagga aagaggaaaa gtattagctg
    27001 aacgttcaaa agaaatggga gcaaaagctt ttattcatta tgcctctaca gatgatttga
    27061 aagatgttaa tatagccaaa agattagaaa tgattaaaga gacttgcaaa aatataggat
    27121 tgccatttgt acaagttaat actccaaata taaatactga agaagacaaa aacaaagtta
    27181 agcagttttt aaatgaagat attgaaaaac aagttaaaaa atatggaaaa gatataaatg
    27241 tatttggtgt aaatgagtat atggatgaag ttatattgac taaggcttta gaattaaagt
    27301 atatagttgc agagcaaagc aatccatcac caatacaaac atatcctagt gttatgggtc
    27361 taaaaatatc tgaaaaagat gctcaaaatt atgataaaat aaacgacatg ataagtgaaa
    27421 aggctaaggc ttttggcatg tcaaatagac ttggtggata tcctatgcca atggatgctt
    27481 ttctaccatc agtagcaatt tatcttgcta ctgaaatggt gaaacaagat ttaacacaag
    27541 aagatgtatg tgacccagat tatttagagg cgtttgcaga attaagattt ggaatcggtt
    27601 cagaatttac tcctttaaca gaggtacttt ataattatca atcagtaatt ttaagccaat
    27661 taatttatta atattaagga agtgtctcaa aatgaacttt ttagtttatg aggcactctt
    27721 tttctattaa atcaaat
//
LOCUS       DACTZW010000053        27610 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.053, whole genome shotgun sequence.
ACCESSION   DACTZW010000053 DACTZW010000000
VERSION     DACTZW010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27610
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.053"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            67..384
                     /gene="flgB"
                     /locus_tag="JAM15_11920"
     CDS             67..384
                     /gene="flgB"
                     /locus_tag="JAM15_11920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgB"
                     /protein_id="HAT6798959.1"
                     /translation="MNTYDIIKMGLDATNLRSQTIANNIANINTEGYKRHYVTFEETL
                     NDAMPKIEEKTDNSKGLRVDGNNVDIEEEKVNQAMATLQYNALISFANGKIAMTKSII
                     SGR"
     gene            392..796
                     /gene="flgC"
                     /locus_tag="JAM15_11925"
     CDS             392..796
                     /gene="flgC"
                     /locus_tag="JAM15_11925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012060427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgC"
                     /protein_id="HAT6798960.1"
                     /translation="MSVFSGMRISTSGLTAESLKMDIISSNVANINATRGPNGEAYRR
                     KVVSFEENYDNKLGMLGVKVTSVEDDKSPLKEVYDPSHPDAKPNGYVEYPNVNILVEM
                     TDLITASRAYDSNVDTLNAQKSMISKALEIGK"
     gene            806..1123
                     /gene="fliE"
                     /locus_tag="JAM15_11930"
     CDS             806..1123
                     /gene="fliE"
                     /locus_tag="JAM15_11930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein FliE"
                     /protein_id="HAT6798961.1"
                     /translation="MPITQINNLMQGAKLDNLIGETKPLTLNNKEEKKNFEDVIIDTI
                     DKVNFQQVTADDMKEKFIKGEDVSMHEVMLIGQEAQLSMQYLIEVRNKIHDAYQEMNK
                     VQI"
     gene            1148..2698
                     /gene="fliF"
                     /locus_tag="JAM15_11935"
     CDS             1148..2698
                     /gene="fliF"
                     /locus_tag="JAM15_11935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body M-ring protein FliF"
                     /protein_id="HAT6798962.1"
                     /translation="MIASFKNKIKEQVAKSRTKISSLKKGTKIALGIGVVAICLALVF
                     TAISASKNKYAVLFSELDVQDAADISAELESKKIDTKVKGSTIYVPRTEVDKLRLELA
                     PSLTGGSKGFALMDDSSSIGLTDEEFQIKKQRMIQGEIEKTIKSFPQVEDTRVHITFG
                     ESSVFEKEAVPGSAAVYLMLKPGTTLEKKQIKSVMALISGSVTNIPEKNVQVIDNKMN
                     LLSEGILEDEDVDENNQPINSGISVDKNKASEQALNKQLEKSILEMLEPIFGKGKVKA
                     TVNADLSFDTAEKTEIKIDPDKVAIKETRSKNSSKSATNNVQGVDANMNNQGNNNGTN
                     TEDSLDESFEYETGKIETRTIVAPGELNRLTASVAIDGKIAKGVQADVEDIVSNAIGM
                     DGARGDTLSVVSMVFDPEGKKEAKQELEEIKKEGFKKNIIKAVIGVVAVVAVGAIGYL
                     IYKKRSEREDMDYEDEDYISKSDSVDKKDNPLLGDDPELTLEEAVKMYAEEKPDQVTE
                     IIKTWLNE"
     gene            2711..3781
                     /gene="fliG"
                     /locus_tag="JAM15_11940"
     CDS             2711..3781
                     /gene="fliG"
                     /locus_tag="JAM15_11940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliG"
                     /protein_id="HAT6798963.1"
                     /translation="MSTEITNVNAFDLSDINESDKNEKVEGEGLKKAAVLLMTLGPNV
                     SSDIIKSLPDKQVQKIGLEIANISSIASKERREILKEFVEINRAKDYVIEGGLEYARE
                     LLSNALGNAKANKLLEGISINTSTKPFKHIIKLDIKKILEILRNESAQTIAVLLAHME
                     PENGAEVLSYLDFDLQNEVAMRISSMGSISPEVIKVIESSLEDKLQSISGDDFKDYGG
                     VSTLVQILINSDRKTEKNILGTIEEQDPDLAAQIKSHIFVFEDIVKLDDISIQKVLKE
                     VTMKDLVYALKGVDDDISDAIYRNQSSRAADALKEEMEMVGVIKVTQVEAAQQKIANI
                     VRKLEREGAITIVRNFGGDFVE"
     gene            3774..4505
                     /locus_tag="JAM15_11945"
     CDS             3774..4505
                     /locus_tag="JAM15_11945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliH"
                     /protein_id="HAT6798964.1"
                     /translation="MNNKIIKSKKASYKGVLDLTIIDKVRVGESNVNKENDCRFKDEV
                     IKEAIESAEIKKNEILEEAKMNAQNIEKQAYEKGYSQGQKNGYEDGYKESYDEYTQRA
                     KDEADFIKNQADLILLQANEKMTEYIKEKNKEIVRLAINMASSVLKKHFEDEESMSDL
                     LKQIIQDYEGSSSFIVRCNSFYKDNIEKEFELFKEETSLKSSVFVIADDSIDKGNAII
                     QKENGRIIVGIDCAMEKLKEELLGE"
     gene            4509..5828
                     /gene="fliI"
                     /locus_tag="JAM15_11950"
     CDS             4509..5828
                     /gene="fliI"
                     /locus_tag="JAM15_11950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein export ATPase FliI"
                     /protein_id="HAT6798965.1"
                     /translation="MYKTDISIDFDKINKKIENLELTISEGRVKKIIGLTVEVEGIKA
                     FVGELCVIYNQVNKPVNCEVVGFKDKEVILMALGELTLIAPGCKVISKGIPLSVMCSD
                     NLLGKVLDGLGNPIDNSDTVLGDRYNLNNEPPDPMKRKKIRNIMETGVRAIDAFTTCG
                     EGQRIGIFAGSGVGKSTTLGMIARNAKADVNVIALIGERGREVLDFIDKDLGEEGMKK
                     SVVVCATSDKAPLVRLKGALTATAIAEYFRDQGKKVILMMDSVTRFAMAQREVGIAIG
                     EPPAQKGYTPSVFAILPKLMERTGTSDKGSITAFYTVLVDGDDFNEPIADTTRGILDG
                     HIVLSRDLANKNHYPSIDVLNSLSRLMNEIASKEDIKIASFARDMLAEYREAEDLINI
                     GAYASGTNKKIDEAIYYHEHIINFLKQGINEKSSFNETISSLRRVFE"
     gene            5859..6305
                     /gene="fliJ"
                     /locus_tag="JAM15_11955"
     CDS             5859..6305
                     /gene="fliJ"
                     /locus_tag="JAM15_11955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012815984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export protein FliJ"
                     /protein_id="HAT6798966.1"
                     /translation="MELDKNFKFRLQKVLDLKIKDEEEIKMEFAKIQQKKIDIETNLE
                     NLESNYSKYSISKNNDSIQNQKITINYLLALNNSIMDLSEELDKSTNELEKARKQLIS
                     KQIERKSLEKLKEKKYGQYYKEEHLKEQNTNDEFASMSYLRNRQVL"
     gene            6333..7538
                     /locus_tag="JAM15_11960"
     CDS             6333..7538
                     /locus_tag="JAM15_11960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-length control protein FliK"
                     /protein_id="HAT6798967.1"
                     /translation="MKIQADSYNIIKDIGNRKSSSKNKNIKNNKFEDNLYKATDHKKV
                     KGRREISKQNISSDKPENSDNECHLDEDKSNHLKDEKTYEKDCSKNNEALQQLLNLLK
                     DNYKKDKDINTILNNIEKLSISDELKQELKLNKNILNKIANQNSELNKANTDHSNDIE
                     NLDIMKLRELLENNADEDIEVISKTTENDIKSIDLYSFDSNRMDNLNSNKQRDDSSDI
                     LEKLAGVNGNKSGNFSQVINKSVDMNKIKNDNVNLKQIESNVIDDSIKAIKHMKTNDI
                     QELTIKLRPKELGDMNIQLLKDGESMRAVVTVFNKDVFDSINKNIADLKQHLELTNVN
                     IKDVSVQMYSDNTNTSDTFDKAFEQQNRQNNQENMSKQNTNDNRNNVVIEDEIKENII
                     DDDRVDLLA"
     gene            7556..8164
                     /locus_tag="JAM15_11965"
     CDS             7556..8164
                     /locus_tag="JAM15_11965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlgD"
                     /protein_id="HAT6798968.1"
                     /translation="MYGIATVLTGTQGNYRSNNLSQLERNINDIANKQVRSKGNQTVT
                     DNGTPIIGQGDDADKDLFMKILVAQMGNQDPMNPQDPTEYVSQLAQFATLEKMSAMNE
                     KLDVLLALSNSTLINSALSMATSLIGKEVEVSGEEKENENIVGVVKSTYIKDGEVHLE
                     LEVDGSDKTVDVKYEKLLKIGEVDENSGEENDSSEHESPEEA"
     gene            8191..9186
                     /locus_tag="JAM15_11970"
     CDS             8191..9186
                     /locus_tag="JAM15_11970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein"
                     /protein_id="HAT6798969.1"
                     /translation="MIKAMYSGVSGMKANQTKLDVIGNNVANAGTTSFKKSSARITDS
                     FYQTVLYASAPTAALGGTNLGQVGVGSKISSINKDMTQGNVQPTNRPSDLMIDGDGYL
                     PVVRQGTVMYTRDGSFNLDTGFKAAAGPLQGVKGGRLVNGDGYMLVGQIMTGKYDANK
                     GTFTPDAKPAAGWPNEPVVIPLQSISPKDGTVQNVLEYNISKDGTIEFLLSDGQRTQF
                     VYDIPDNSEVGVVPNPAIATDSGKLQKVQTYAFQNPAGLDAEGGNLFKPSANSGDPQI
                     AGATGTIIQGAIEASNVDIAEEFTEMIIASRSFQANSKIISTSDEILQEIINLKR"
     gene            9199..9402
                     /locus_tag="JAM15_11975"
     CDS             9199..9402
                     /locus_tag="JAM15_11975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlbD"
                     /protein_id="HAT6798970.1"
                     /translation="MIRVTDLNGRKYILNSDLIVRIDSVPESRILLTTGEKNLVKESV
                     DEIVDKVIKYKRKINVGYIRSEK"
     gene            9402..10220
                     /locus_tag="JAM15_11980"
     CDS             9402..10220
                     /locus_tag="JAM15_11980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901756.1"
                     /note="Homolog of MotA, appears to be involved in motility
                     on surfaces and under different ionic conditions. With
                     MotS (a MotB homolog) forms the ion channels that couple
                     flagellar rotation to proton/sodium motive force across
                     the membrane and forms the stator elements of the rotary
                     flagellar machine; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="motility protein A"
                     /protein_id="HAT6798971.1"
                     /translation="MKKTDLLTFIGLIVSTVLVLVGAAKGSSSGLKNFFDVSSILITV
                     LGSFGALMITFTIDDIKLIKNALQYSFKTMSVSKLDLLEQFKTLSKKARKEGLLSIES
                     DVMGIEDPFMKKGLELCIDGLEINEIRSILELEIDSVEDTNNRYSKLFKTWGTFAPAF
                     GMLGTLIGLIQMLADLTSPDLIASGMGKALITTFYGSLLANIALNPIAYNIDEKTEKE
                     IYVKEMMLEGIISIQSGESSIVVEERLATYLSNNEKLEIMKSNKNAERAMSNGA"
     gene            10210..10905
                     /locus_tag="JAM15_11985"
     CDS             10210..10905
                     /locus_tag="JAM15_11985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HAT6798972.1"
                     /translation="MARKKNKKKDEINPDAWLATYSDTITLILTFFVLLYATSVVDME
                     KFKNIANALKGQFSGTSMFSTGSSTSEKSPIESVLVDKNDKSNLKQDLKDKVNNSNLQ
                     NSVTVKDDSRGILLELDDSILFDSGISELKADSKATLNKVYDMIKMIKNKIVIEGHTD
                     NVPVKSSTHESNWDLSSSRAVSVVRYFVEEKGMDPKLFSATGCGEYQPLVSNETAKGR
                     AENRRVNILITID"
     gene            10917..11360
                     /locus_tag="JAM15_11990"
     CDS             10917..11360
                     /locus_tag="JAM15_11990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body-associated FliL family
                     protein"
                     /protein_id="HAT6798973.1"
                     /translation="MFKNKKIIIIILILIIFSAGAGFFILGEGGNKQIDKIAGLFIPT
                     RKGKDEVKTENLDLEEMVLKLADEGVRYLKVSITVSYDSSYKDIEKNTPLIRDNIINC
                     FMAKRADDFTADNLKNIKEEIKNTLNIQLGENVIQNIYFTNIVVQ"
     gene            11375..11749
                     /locus_tag="JAM15_11995"
     CDS             11375..11749
                     /locus_tag="JAM15_11995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliO/MopB family protein"
                     /protein_id="HAT6798974.1"
                     /translation="MILYLLKILICIPIILILIVLSLKISQGTLLKKYNDKYIKILDI
                     VNISKNNSIIILKIGEEGCIMASSSSSMNKIKDLTKEEILKIENDIKERNFKIQDFKM
                     ERIKKKYDFSRYIGKFTKKEDK"
     gene            11750..12415
                     /gene="fliP"
                     /locus_tag="JAM15_12000"
     CDS             11750..12415
                     /gene="fliP"
                     /locus_tag="JAM15_12000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425215.1"
                     /note="The bacterial flagellar biogenesis protein FliP
                     forms a type III secretion system (T3SS)-type pore
                     required for flagellar assembly; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system pore protein
                     FliP"
                     /protein_id="HAT6798975.1"
                     /translation="MELLSKLPLADVPYTSSMQLFLFLTALMFLPFVMFMMTSFVRIV
                     ISLSFLKSALGAQQAIPSQILVGLAIVLTIFIMRPVLNEINEKALQPYMKEEVTMEEA
                     MKEAEGPIKEFLLKQTRQTDLDLFVEQAGLKEKKLTRENIPLSVVVPAFAISELKTAF
                     QIGFLIYIPFLIIDLVVASVLMSMGMFMLPPVMISLPFKLLLFVMVDGWNLIVKTLIL
                     GFG"
     gene            12428..12697
                     /gene="fliQ"
                     /locus_tag="JAM15_12005"
     CDS             12428..12697
                     /gene="fliQ"
                     /locus_tag="JAM15_12005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015616056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliQ"
                     /protein_id="HAT6798976.1"
                     /translation="MSEFMIMSVLKNGMFTGAMIAAPVLIVSLVVGLLISVFQATTQI
                     QEQTLTFVPKLIAILLVVAIGGSWMLHTLISFTSEIFNMMSLITK"
     gene            12709..14523
                     /locus_tag="JAM15_12010"
     CDS             12709..14523
                     /locus_tag="JAM15_12010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused FliR family export protein/FlhB family
                     type III secretion system protein"
                     /protein_id="HAT6798977.1"
                     /translation="MIFVFIRIVAFFGTLRILFPAGTPALFKSLFAIIISILISSTMQ
                     IEYATNIDNIVLFTLYGINETITGIMLGYITNLCFYSIRMAGSMMDQQMGLSMINMFD
                     PNSMTQTTLIDNLMNWTALMIFFSMDGHHVLIRGIRYSFELIPIGKSFVDNNIDYIIN
                     IFVQCFLTGFKIAIPIVLCLLMADFILGLISRSVPQLNVMIIGMPLKILVGIALFIIS
                     IPLIVNQISHLLSQIPKMYEGTFALAPMFFMGSTDKTEEATPKKKGEQRKKGNIAKSK
                     ELPIAMTLLAFTLLVPTLFSYVVDTLKSSLNYFLSLDFYMNINYSSIEKLVIAGLMDF
                     FKIFLPIAIPFLILGIVANLFQVGILFTGETLKPNLSKLNPVSGFKNMFSMRSLSTLI
                     KDTAIISILAYIGYTFFQDNYLDILKLGNIYLPTLMYTVKDLVYSILSKICVAMIVIA
                     VADYVYQRYSHKKQLRMTKQEVKDEYKNSEGDPEIKAKIKQKQRQISSQRTMQAVPSA
                     TVIVTNPTHLSIAVRYEKGKDQAPVVVAKGADYLAFKIREIAKGNDIPIIENKPIARL
                     LYKQVEIDQEIPEDMYQAFAEILVAVYKIKNRYKVPKR"
     gene            14532..16607
                     /gene="flhA"
                     /locus_tag="JAM15_12015"
     CDS             14532..16607
                     /gene="flhA"
                     /locus_tag="JAM15_12015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
                     /protein_id="HAT6798978.1"
                     /translation="MNKFNLKENMDVIVAFGVVGIVLMMIVPLPTFILDILLAINISL
                     SVLILLMTLFTTNVLDLSIFPTVLLVTTLFRLGLNLSSTRLILTQGYAGEVIEAFGSF
                     VVGGNYVVGIIIFLIILIVQFVVITNGSGRVSEVTARFTLDAMPGKQMSIDADLNAGV
                     IDDKTARKRRKELQQEADFYGSMDGANKFVKGDAIAGLIVTAINIIGGIVIGAVMLNM
                     TLMGAAQTYVRLTIGDGLVSQIPALLISTSAGIIVTRASTDENFGGLVGKQLTAIPKA
                     VMMTGCVLIVLGMMPGLPKPAFFSLGIGAIAAGYFLGREKKDTLEDLEFEKPDMVNPD
                     KNEVEDVTNLINVELIEIEIGYGLISLADESAGGDLLQRIASIRRQCAIDMGIVVQPI
                     RIRDNLQLNPNQYNIKIKGNVVGGYEIMPNMVLCMDPMNQGFSIFGIKTIEPTFGIEA
                     LWIESDKVEDAELKGYTVVDSSTILITHLLDIIKSNAHELLGRQEVKTIIDAARENYS
                     AVVDELIPDLMTLGEIQKVLKNLLREKVNIKDRVTILETLADQSRNTKDIELLTEYVR
                     IALARSICNNLVDEDKAIIVATLSPETEELVSNNLQRSVNGTYPAVDPENTNKIFESI
                     QEVMNNVYFNHNIPVIVVSPKIRAPFRKLVEIVYPNLTVLSLNEIPNDIKIKAEGVVS
                     IYDDEKVYS"
     gene            16582..17598
                     /gene="flhF"
                     /locus_tag="JAM15_12020"
     CDS             16582..17598
                     /gene="flhF"
                     /locus_tag="JAM15_12020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhF"
                     /protein_id="HAT6798979.1"
                     /translation="MMTKKYTANTIQDAMNLAKMELGDNITLIDKKEVRKSGIQGIFS
                     KKDIELTIGWEKRENVEQKDLKREIEQLKLIINNMGFDNKNDNDIDKICKNLLSLELN
                     EEIVESIRIDLQEMKFNGIDTSKNLVEILKKKIKIENQAINGKIALVGPPGVGKTTTI
                     AKLAAKLVFEENKKVGVITIDTYRIGAVEQLKIYTDIMNIPFKGVISPDEMELALDEM
                     KDCDVVLIDTTGRGYKNSMQILEIKNLIDKAETDNIHLVVNCTTRESDTKAIIDSYRN
                     VNFKSLIITKLDETITYGSIFNIMNYAQKPISYITTGQNVPDDIIKPNEDKIIRLLLG
                     VESI"
     gene            17595..18473
                     /locus_tag="JAM15_12025"
     CDS             17595..18473
                     /locus_tag="JAM15_12025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MinD/ParA family protein"
                     /protein_id="HAT6798980.1"
                     /translation="MIDQAQILRKMAMEKRGLDEFIVENENVPKIITIASGKGGVGKS
                     NLATNLSICLTKLNKKVLILDADIGMSNIDIIMGVNVKGTIIDVINGKKNIEDIISQT
                     KYGVNIISGGSALNHIEDFTEAQRNKFIHSIEQIHDVDFIIIDTGAGMSKSLLSFIYC
                     STEFFLITTPEPTSLTDAYSLLKAISNFGIKRSANIIINRVIDLEEAKSTYKRIKMVV
                     DKFLNLNLELYGYIIDDKKVSLCVKKQIPFILEYPTSIASKCIIAIAKRMVSQSREDI
                     VDNKSFLRKMFSIFKS"
     gene            18487..19188
                     /locus_tag="JAM15_12030"
     CDS             18487..19188
                     /locus_tag="JAM15_12030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliA/WhiG family RNA polymerase sigma factor"
                     /protein_id="HAT6798981.1"
                     /translation="MNREELIKENMPLVKSIARKFFIPGKGFEYQDLVNSGVIGLIDA
                     INKFDAEKGAKFSSYSYIKIKSAILDEIRNQSPISKHNLTKVNKYNRVVEKLQSKLLR
                     EPTSYEIAKELNVSEKELHDIESNIDMLNIVSLNYVIFEDTNETVQDVISDREEEAPE
                     NIIEEEEKLEILSKAISNLNEREKLILSLYYYEDLNLKEIGKVLGVSESRVSQLHRKS
                     IRNLRNKIKELKYSI"
     gene            19204..19626
                     /locus_tag="JAM15_12035"
     CDS             19204..19626
                     /locus_tag="JAM15_12035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HAT6798982.1"
                     /translation="MIQIILIVVSILIIVTIVINLHKESKNKDNRYFDKIFEQEYEAN
                     DRLIIAEKRRFFLDKVLAEIRSNNHIKVYENYNLIKANEERKENIFIESKKEVRQENE
                     LSLKVKHLISSGYDDVEICKMLDIGKGELSLIRSCYKI"
     gene            19611..19796
                     /locus_tag="JAM15_12040"
     CDS             19611..19796
                     /locus_tag="JAM15_12040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HAT6798983.1"
                     /translation="MLQNIRILLCDKKVFLGIGIGILISTLCIMLFSNNDMSKAEIEK
                     KARALGMKYTSEMKVLE"
     gene            19837..20610
                     /locus_tag="JAM15_12045"
     CDS             19837..20610
                     /locus_tag="JAM15_12045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgG"
                     /protein_id="HAT6798984.1"
                     /translation="MIRGLYTAVSAMITNQQKQNVVVNNLANMDTNGYKSKQLLTKSF
                     DELKLEGYNNYANGTKQKQIIGDISPGISMDETITNFNQGPIKTTDNKMDVAIQGKGF
                     FLVSDAAGNQFYTRNGNFRTDNQGDLITSEGYYVLGTNTATGAVGHINVGNQKFEVAK
                     DNTISLDGNAMYKFNIVDFNDYNNLKKEGDNLYSGGGAMKVNNALTIQSAIESSNVDM
                     VSEINNMMTISREYEANQKIIQAMDSKLAKIASEIGSVR"
     gene            20631..21392
                     /gene="flgG"
                     /locus_tag="JAM15_12050"
     CDS             20631..21392
                     /gene="flgG"
                     /locus_tag="JAM15_12050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgG"
                     /protein_id="HAT6798985.1"
                     /translation="MYTMFYTSKTALSANQSKLDIISNNIANSDSTGYKKINMEYSDL
                     VDEVLNRPSYPTNGNDISTGTGAKATAPMRIYEQGALAPTDSKSNLAIDGEGFFRVIR
                     KDGTYAYTRNGGFNIDGLGKIVDDNGNILDVQFDAGYNYNNTNIDSTNLTVSRNGELF
                     VDNKKIGKINLYQPIGTQNFISEGDSLFVATDAAQIKQVEKVDIVQGYRERSNVSLQE
                     EFVDLIATQRAFQMNSKGIKTADEMWQIANNLRAK"
     gene            21415..22296
                     /locus_tag="JAM15_12055"
     CDS             21415..22296
                     /locus_tag="JAM15_12055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliM"
                     /protein_id="HAT6798986.1"
                     /translation="MNDMKEYDFGKPQSYSRENLTCLNFLLAEFCKKYKNYIIYELKC
                     NSSMIVDSIDQVNYQTFLDRVTSSCVVVQNAMEPVMKNFSFRIDRSVADMWIDITSGG
                     TGVIKDNDRELTELDKKVLLHLMDDLVRNMHLFEGFENIQVLDTHTHINLPQLCSPTA
                     PVCVVDLKVLNDNEYIGSVSLCFPYNGLEALLESISVIEFFDNDVGDDSEEFTKKIYN
                     SVSNIELSVIAEIGKVSINVEDLLKLEVGDVIVTNKKINDYIDIFVENSKSYTATPGF
                     ISSKKGVKINDAVGKEV"
     gene            22299..22673
                     /locus_tag="JAM15_12060"
     CDS             22299..22673
                     /locus_tag="JAM15_12060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliN"
                     /protein_id="HAT6798987.1"
                     /translation="MDNSNLISDEEAKMLLNDKVESEVDGDDELALDVSEVNRNNIQR
                     ILDLKLELSVVIGRTKMTLRDILNLHKGSLIELDTLADQDVEILIDNKVLAYGKVVVV
                     DLNFGVKITSIVSEEDMVKSLV"
     gene            22705..24108
                     /locus_tag="JAM15_12065"
     CDS             22705..24108
                     /locus_tag="JAM15_12065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAT6798988.1"
                     /translation="MVLILNLNDIKKDILKLNKKDSCSLYNESINNINNNCISTGLKF
                     LKQARDLNPDDVDILNLTGLVNLLKCNFDDAVESFYKSSLCEKTALCEKYINMLTSEE
                     FLIFFEKYNQLIRLINKGMYKEAIQGFKLITDQYCDLIEPYELLALLYDKEEEYIKFD
                     ECLEVLKIIDKENYLLNQENNTLDMYNSANIQTKSNVKVDDYKNEFLHKSSSNHKIND
                     YNNVTKEKSSSKNQKSSDSNKKKSIKKNKYLYIAIILGILLVGQSIYSSYKMNNLTDK
                     ISKNNETKNEESIDSNLIKKENNIEENEDMSKASNINKSNKNINKEDDVKSKKNTVEN
                     EDDKDSDLFTEDELMSKANTLKSEKKTKSSIQLYKKVADIGENKGNTSEATYQVAILS
                     EKLKDYKTAEEYYKMYVENYSEKDAYFDESYYNLGMMYYNNGDLKNSKLTLKKLVNKV
                     PNSMYNNSKVKEILKEE"
     gene            24224..26161
                     /gene="htpG"
                     /locus_tag="JAM15_12070"
     CDS             24224..26161
                     /gene="htpG"
                     /locus_tag="JAM15_12070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008428053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HtpG"
                     /protein_id="HAT6798989.1"
                     /translation="MEFEKGSISIHTENIFPIIKKWLYSDKDIFIRELISNGCDAVSK
                     HKRLVSLGEISENKSSDYKITVSVNKGEGTLKFIDNGIGMTEEEIKKYINQVAFSGAE
                     DFFNKYKDKMEESNDIIGHFGLGFYSAFMVSKKVQIDTLSYTEGATPVRWISEGGTEY
                     EISESDARNDRGTTITLFIDDDSKEFLDEFTVRGIINKYCSFLPVEIYLEDVERLERE
                     AKEAEEKAKKQKEDGKEEIVDAKVIEPLNDTNPLWLKSPKDCTDEEYKEFYRKVFNVF
                     DEPLFWIHLNVDYPFNLKGILYFPKLKNEFELTEGKVKLYNNQVFVADNIKEVIPEFL
                     LLLKGVIDCPDLPLNVSRSFLQNDRDVSKISKHIIKKVADKLKSLCKNEREEYNKFWD
                     DIQIFIKYGCLKDESFYEKVKECILFKTIDDEYITLQDYLEKCKDKHENKVFYVSDKE
                     QQSQYIKLFKEYDLSAVVLNSSIDTHFISFMEYKENGVKFNRIDADLSDVLKDKNENK
                     DSEENKEEIAKIEGLFKEAVGERVKNYSVEGLKNEDTPAMVLVSEQSIRMAEMQSRFA
                     GMDLGMNFEEEKTLVINENSPIIKKLVSLKDDEEKKDKITLICNQIADLALLSNKELK
                     PDELDSFVQRSNKLMSLLIEL"
     gene            26549..>27610
                     /locus_tag="JAM15_12075"
     CDS             26549..>27610
                     /locus_tag="JAM15_12075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015394701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HAT6798990.1"
                     /translation="MNFNYNLPVNILFGRGRINDVGKEVSKYGKKVLIVTGKNSTKKT
                     GLLDKTIDLLKDSKIEYEVFDRVEQNPLITTIYSGVEIIKSTGCDCVLGLGGGSIMDA
                     AKSIAFSYKNPGDLNDYIFGIRQGEEALPIILVPTTSGTGSEGNCFAVLTNSETKDKK
                     SIKKNSMYAKASIIDPELMVTMPKHIIASVGFDALAHNMEAYLSNGRNPLADVQAIYG
                     IELISENLIKVYNDVNDLEAWEKITLASTIGGMTIGTAGTALPHGMEHPVSGLRDVMH
                     GKGLAALTPTIIESSWDIDIERFGNISKVLGGTCAEDCSDAIRNFLKKIDLDIKLSDL
                     GIEKSDIDWLTDNCMKISVA"
BASE COUNT        11409 a         2946 c         5156 g         8099 t
ORIGIN      
        1 aatagagcaa cttcattttt tattaataag caaaataaat aaaatatatt ttgaggagga
       61 gtgagtgtga atacatatga cattataaaa atgggattag atgcaactaa tttaagaagt
      121 cagacaatag caaataatat agccaatata aatactgaag gatataagag acattatgta
      181 acttttgaag aaacattaaa tgatgctatg ccaaaaatag aagaaaaaac agacaattct
      241 aaaggattaa gagtggatgg caataatgta gatatagaag aagaaaaagt aaatcaagca
      301 atggcaacat tacaatataa tgctttgata agttttgcaa atggaaaaat agcaatgact
      361 aaatcaataa taagtgggag gtaattaaaa ggtgagtgtg ttcagtggaa tgagaatatc
      421 tactagtgga ttaacagcag aaagcttgaa aatggatatc atatcgtcca atgtagctaa
      481 tataaatgcc acaagaggtc caaatggaga agcatatagg agaaaagttg tttcatttga
      541 agaaaactat gataataaat taggtatgct aggagtaaaa gttacatctg ttgaagatga
      601 taaatcacct cttaaagaag tatatgaccc atctcatcca gatgcaaagc caaatggata
      661 tgtagaatat ccaaatgtaa atatattggt agaaatgaca gatttaataa cagcttcacg
      721 agcatatgat tctaacgtag atacattgaa tgctcagaag tctatgatat caaaagcttt
      781 ggaaatagga aagtagggat aaattatgcc aattacacaa attaacaatt taatgcaagg
      841 tgcaaagtta gataatttga ttggagaaac aaaaccatta actcttaata ataaagaaga
      901 aaaaaagaac tttgaagatg taataataga tactatagat aaagttaatt ttcaacaagt
      961 gacagcagat gatatgaaag aaaaatttat aaaaggcgaa gatgtttcta tgcatgaagt
     1021 tatgttaata ggtcaagaag cacagctatc tatgcaatat ttaatagaag ttagaaataa
     1081 gattcatgat gcatatcaag aaatgaataa ggtacaaatt tagccttttg aacaggagta
     1141 ataatcaatg atagccagtt ttaaaaataa gattaaagag caagttgcta aatctaggac
     1201 aaagataagt tctctaaaaa agggaactaa aatagcatta ggtatagggg ttgttgctat
     1261 atgtttagcg ctagtattta cagcaatatc tgcgagcaaa aataagtatg cagtcttatt
     1321 ttcagaacta gatgttcaag atgctgcaga tatatcagca gaattagagt ctaaaaagat
     1381 agatactaag gtaaaaggta gtacaattta tgtacctaga acagaagttg ataagttaag
     1441 actggagtta gcaccaagtc ttacaggtgg ttctaaagga tttgcactaa tggatgatag
     1501 ttcatcaata ggtcttactg atgaagagtt tcagattaag aagcaaagaa tgatacaagg
     1561 tgaaatagaa aaaacaataa agagttttcc acaagtggaa gatactagag tacatataac
     1621 atttggagag tcatcagtat ttgagaagga ggctgttcca gggagtgcag cagtttattt
     1681 gatgttaaaa ccagggacta ctttagaaaa aaaacaaata aagtctgtta tggcacttat
     1741 atcaggaagc gttacaaata taccagagaa aaatgttcaa gtcattgata acaaaatgaa
     1801 tttattatct gaaggtattt tagaggatga agatgttgat gagaataatc agccaataaa
     1861 tagtggcatt agtgttgata aaaataaggc atctgaacaa gcattgaata aacaactaga
     1921 aaagtctatt ttagaaatgc tagaaccaat atttggtaaa ggaaaggtaa aagctacagt
     1981 aaatgctgat ttaagttttg atacagctga aaaaactgag ataaaaattg accctgataa
     2041 agttgcaata aaggagacaa ggtcgaaaaa ttcatctaaa tctgctacaa ataacgttca
     2101 aggtgtagat gctaacatga ataaccaagg aaataacaat ggtactaata cagaagatag
     2161 tttagatgag agttttgagt atgaaacagg taagattgaa actcgcacta tagttgcgcc
     2221 tggagaactt aataggttga cagcttctgt tgcgatagat ggaaaaatag ctaaaggtgt
     2281 tcaagctgat gtagaggata ttgttagtaa tgctataggt atggatggag cgaggggaga
     2341 tactcttagc gttgtttcaa tggtatttga cccagaaggg aagaaagagg ctaaacaaga
     2401 gctggaagag attaaaaaag aaggatttaa aaagaacata ataaaagcag ttattggagt
     2461 agtagcagtg gtagcagttg gagctattgg atacttaata tataagaaaa gaagtgaacg
     2521 agaagatatg gattatgaag atgaagatta tatttctaaa tctgattctg ttgataagaa
     2581 ggataatcct ctattaggag atgacccaga actgacatta gaggaagctg ttaaaatgta
     2641 tgcagaagaa aagccagacc aagtaacaga gataataaaa acttggttaa atgagtaagg
     2701 gggatagaaa gtgtccacgg aaattacaaa tgttaatgcg tttgacttaa gtgatataaa
     2761 tgaaagtgat aagaatgaga aagtagaagg tgagggttta aaaaaagctg ctgtattatt
     2821 aatgacatta ggaccaaatg tgtctagtga tataataaaa agccttcctg ataaacaagt
     2881 tcaaaaaata ggtttggaaa ttgcaaatat ttcttcaata gcttcgaaag aaagaagaga
     2941 aatcttaaaa gagtttgtag aaataaatag ggcaaaagat tatgttatag aaggtgggct
     3001 tgaatatgca agagagttgt taagcaatgc tttaggaaat gctaaagcaa acaaattact
     3061 tgaaggtata tcaataaata caagtacaaa accttttaaa catatcataa aactagatat
     3121 aaagaaaata ttagaaatac ttaggaatga aagtgcacaa actatagccg ttttacttgc
     3181 acatatggag ccagaaaatg gagcagaagt tttatcatac ttagattttg atttacaaaa
     3241 tgaagtagct atgagaataa gctcaatggg ttcaatatct ccagaagtaa taaaagtaat
     3301 tgaaagttca ttagaagata aattacaatc aataagtggt gatgatttta aggattatgg
     3361 aggagtgtct accttagttc aaatattgat taactctgat agaaaaacag aaaagaatat
     3421 tttgggaact attgaagaac aagacccaga tttagcagct caaattaaat ctcatatatt
     3481 tgtctttgaa gatattgtca agttagatga tataagcata caaaaagtgt taaaagaagt
     3541 cactatgaag gatttagtat atgccttaaa aggtgtggat gatgatattt cagatgctat
     3601 atatagaaat caatcttcta gagcagcaga tgcacttaaa gaagaaatgg aaatggttgg
     3661 tgtcataaaa gttacgcagg ttgaggctgc tcaacaaaag atagcaaata tagtaagaaa
     3721 acttgaaaga gaaggtgcca taactattgt aaggaatttt ggtggtgact ttgttgaata
     3781 ataagattat taaaagtaaa aaagcatcat ataaaggagt gctagattta accataatag
     3841 ataaagttag agtgggagaa tcaaatgtaa ataaagaaaa tgattgtaga tttaaggatg
     3901 aggtaataaa agaagctata gaatctgctg agataaaaaa gaatgagata ttagaagaag
     3961 caaaaatgaa tgcacaaaat atagaaaagc aagcatatga aaaagggtat agtcaaggtc
     4021 aaaaaaatgg atatgaagat ggatataaag agtcatatga tgaatatacc caaagagcta
     4081 aagatgaagc agattttata aaaaatcagg cagacttaat actattacaa gctaatgaga
     4141 agatgactga gtacataaaa gaaaaaaata aagagattgt aagacttgct attaatatgg
     4201 ctagttctgt tctaaaaaag catttcgaag atgaagaatc tatgagtgat ttgttaaagc
     4261 aaattattca agattatgaa ggaagtagtt catttatagt aagatgtaat tctttctata
     4321 aagataatat agagaaagag tttgaattat tcaaagagga aacatcacta aaatcaagtg
     4381 tatttgttat tgcagatgat agtatagata aaggcaatgc tatcatccaa aaggaaaatg
     4441 gaagaataat agttggtatc gattgtgcta tggaaaaact aaaagaagaa ttgcttggtg
     4501 aataaagtat gtataaaact gatatatcta tagattttga caaaataaat aagaaaatag
     4561 aaaatttaga actcactata tcagaaggta gagtaaagaa gataatagga cttactgtag
     4621 aagttgaagg aataaaagct tttgttgggg agttatgtgt tatatacaat caagtcaata
     4681 aaccagtgaa ttgtgaagta gtgggtttta aagataaaga agttatatta atggcgttgg
     4741 gagagctaac attgatagct cctggttgta aagttatttc taagggaata cctttaagtg
     4801 ttatgtgtag cgataattta ctaggtaaag tacttgatgg tcttggaaat cctatagaca
     4861 actcagatac tgttttagga gatagataca acttgaacaa tgaacctcct gacccaatga
     4921 agagaaaaaa gatacgaaat ataatggaaa caggtgtaag agcaatagat gcatttacta
     4981 cttgtggtga aggacagaga atcggcatat ttgcaggaag tggagtaggt aagagtacga
     5041 ctctaggtat gattgctagg aatgcaaaag cagatgtaaa tgtaattgct cttattggag
     5101 aaagaggaag agaagtacta gattttattg ataaagattt aggtgaagag ggaatgaaaa
     5161 aatctgttgt tgtgtgtgca acatcagata aagcccctct ggttagatta aaaggtgctc
     5221 ttactgctac tgcaatagca gaatatttta gagatcaagg taaaaaagta atacttatga
     5281 tggattcagt aactagattt gctatggcac aaagagaagt tggtatagca ataggagagc
     5341 caccagccca aaaaggatat acaccatctg tatttgccat tttgccaaaa cttatggaga
     5401 gaacagggac atcagataaa ggttctataa ctgcatttta tacagtatta gttgatggag
     5461 atgactttaa tgagccaata gcagatacaa caagagggat acttgatggt catatagttt
     5521 tatctagaga cttggcaaat aagaatcact atccttctat agatgtattg aacagtttaa
     5581 gtagacttat gaatgagatt gcttcaaaag aagacataaa aatagcatct tttgcgagag
     5641 atatgcttgc tgagtataga gaagcagaag atttgataaa tataggtgca tatgcttcag
     5701 gtacaaacaa aaaaatagat gaagcaatct attatcatga gcatattatt aattttttaa
     5761 aacaagggat aaatgaaaag agttctttta atgaaactat aagtagtttg agaagagttt
     5821 ttgaataaac aattaaaaaa atatttgaat aggttgtgat ggaattggat aaaaatttta
     5881 agtttagatt acagaaagtt ttagacttaa aaataaaaga tgaagaagag ataaaaatgg
     5941 aatttgctaa gattcaacaa aaaaaaatag atatagagac taatttagaa aacttagaaa
     6001 gcaattatag caaatattct ataagtaaaa ataatgatag tattcaaaat caaaaaataa
     6061 ctattaacta tttgctagct ttaaacaatt ctataatgga tttatcagaa gagctggata
     6121 agtctacaaa tgaacttgaa aaagctagaa aacagcttat aagcaagcag atagagagaa
     6181 agtcattaga aaaattaaaa gaaaaaaaat atggacagta ttataaagaa gaacatttaa
     6241 aagaacaaaa cactaatgat gagtttgcaa gcatgagtta tttgagaaat agacaagttc
     6301 tataaaatag taggaagtga ggatattatt gtatgaagat acaagcagat tcttataata
     6361 ttattaaaga tattgggaat agaaaaagct catctaagaa taaaaatata aaaaataata
     6421 aatttgaaga taatctatat aaggcaacag atcataaaaa ggttaaaggt agaagggaaa
     6481 taagtaagca aaatattagc tcagataaac cggaaaatag tgataatgag tgtcatttag
     6541 atgaagataa aagtaatcac ttaaaagatg aaaagacata tgaaaaagat tgtagtaaga
     6601 ataatgaagc tttacagcaa ttactgaatc ttttaaaaga taattacaaa aaagataaag
     6661 atataaacac tatattgaat aatatagaaa aactaagtat atcagatgaa ttaaaacaag
     6721 aacttaagct taataaaaat atattaaata agattgcaaa tcaaaattca gagctaaata
     6781 aagccaatac agatcactct aatgatatag aaaatttaga cataatgaag ttaagagaac
     6841 ttttagaaaa taatgcggat gaagatattg aagtaattag taaaactaca gaaaatgata
     6901 ttaaaagtat agatttgtat agttttgata gtaatagaat ggataatctt aactcaaata
     6961 aacaaagaga tgatagttct gatattttgg aaaaactagc aggggtcaat ggaaataaga
     7021 gtgggaattt tagtcaagta ataaataaaa gcgttgatat gaataaaatt aaaaatgata
     7081 atgtcaattt aaaacagata gaatcaaatg taatagatga ctctataaaa gctattaagc
     7141 atatgaaaac aaatgacata caagaattga caattaaatt aagaccaaaa gaattaggag
     7201 atatgaacat acaattgtta aaagatggtg aaagtatgag agctgttgtg actgttttca
     7261 ataaagacgt ctttgactct ataaataaaa acatagcaga tttaaagcaa catcttgaac
     7321 ttacaaatgt aaatataaaa gatgtatcag tgcaaatgta cagcgataat acaaatacat
     7381 ctgatacctt tgataaagca tttgaacaac agaatagaca aaataatcaa gaaaacatga
     7441 gtaagcagaa tacaaatgat aatcgtaaca atgtagtcat agaagatgag attaaagaaa
     7501 atattattga tgatgataga gtagatttac tagcttaata agggggaagt attgcatgta
     7561 cggaatagca acggttttga ctggaactca gggaaattat aggtcaaata atttaagcca
     7621 acttgaaaga aatattaatg atattgccaa taaacaagtt agaagtaaag gaaatcagac
     7681 agtaacagac aatgggactc caattatagg acaaggtgat gatgctgata aagacttgtt
     7741 tatgaagata cttgtagcac agatgggtaa tcaagaccca atgaatccgc aagacccaac
     7801 agaatatgtg tcacaattag cacagtttgc aactttagaa aagatgtcag ctatgaatga
     7861 gaagctagat gtacttttag ccttaagtaa ttccactcta ataaactctg ctttgagtat
     7921 ggcaacatca ttaattggta aagaagtaga agtatctggg gaagagaaag aaaatgaaaa
     7981 cattgtagga gtagtaaagt ccacatatat aaaagatggg gaagtacact tagaattaga
     8041 agtagatgga agtgacaaaa ctgtagatgt taaatatgaa aaattactta aaataggaga
     8101 ggtagatgaa aattcaggag aagaaaatga ctcttcagaa cacgaatctc cagaagaagc
     8161 ataatattaa atgagaaaag aggtaaattc atgataaaag caatgtattc aggtgtaagt
     8221 ggaatgaaag caaatcaaac aaaactagat gtaataggta acaatgtagc caacgctgga
     8281 actacttctt ttaagaaaag ttcagctaga ataacagatt cattttatca aactgtacta
     8341 tatgcaagtg ctccaacagc ggcattaggg ggaacaaact taggacaagt aggtgtaggt
     8401 agtaagatat caagtataaa taaagatatg acacaaggaa atgtacaacc aactaataga
     8461 ccatctgatt taatgataga tggagatgga tatcttccag tagtaagaca aggtacagtt
     8521 atgtacacta gagatggttc ttttaactta gatacaggat ttaaagcagc agcaggacct
     8581 ttgcaaggtg tcaaaggtgg aagacttgta aatggtgatg gatatatgct tgtaggacaa
     8641 ataatgactg gaaaatatga tgcaaataaa ggaactttca caccagatgc aaaacctgct
     8701 gctggttggc caaatgaacc agttgttata ccacttcaaa gtataagccc taaagatggt
     8761 acagttcaaa atgtattaga gtataacata tcgaaggatg gaacaataga atttttatta
     8821 agtgatgggc aaagaactca gtttgtgtat gatattcctg acaactctga agtaggagta
     8881 gtaccaaatc ctgcaatagc aactgactct ggtaaacttc aaaaagtgca aacatatgca
     8941 ttccaaaatc cagcaggact agatgcagaa ggaggaaact tgtttaaacc atcagcaaac
     9001 tcaggagacc cacaaatagc aggagctaca ggaacaataa tacaaggggc aatagaagct
     9061 tccaatgtag atatagcaga agaatttaca gaaatgataa tagcaagtag gtctttccaa
     9121 gcaaacagta aaataatatc gacatcagac gagatacttc aagaaataat aaatcttaag
     9181 agatagtagg tacatattat gataagagta acggatttaa acggaagaaa atacatatta
     9241 aattcagacc ttatagtgag gattgattct gtaccagaaa gtaggattct ccttacaaca
     9301 ggagaaaaaa accttgtaaa agagtcggta gatgagatag tagataaagt aataaagtat
     9361 aaaagaaaaa taaatgtagg ttatattagg agcgaaaaat aatgaaaaaa acagatttac
     9421 tgacatttat tggactaata gtatctacag tattagtttt agttggtgcc gcaaaaggaa
     9481 gtagttcagg gttaaagaat ttttttgatg tttcatcaat attaatcaca gtgcttggtt
     9541 catttggagc tctaatgatt acatttacta tagatgatat aaaacttata aaaaatgcat
     9601 tacaatactc atttaagaca atgagtgtat caaagttaga tttactagaa caatttaaaa
     9661 cactttctaa aaaagctaga aaagaaggtc ttttatcaat agaaagtgat gtaatgggaa
     9721 tagaagatcc atttatgaag aaagggttag agctatgtat tgatggattg gaaatcaatg
     9781 agataaggtc catcttagaa ctagagatag attctgttga agatacaaat aacagatact
     9841 ctaaactatt taaaacttgg ggaacctttg cacctgcctt tgggatgttg ggaacactaa
     9901 taggtttaat acaaatgtta gctgacctta catctccaga tttaatagca tctggtatgg
     9961 gaaaggcatt aattacaacg ttttatggtt ctttacttgc caatatcgct ttgaacccaa
    10021 ttgcatataa tatagatgag aagactgaaa aagaaattta tgtaaaggaa atgatgttgg
    10081 aaggtataat aagcatacaa tctggggaga gcagcatagt agttgaggaa cgtttagcta
    10141 catacctttc aaacaatgag aagttagaaa ttatgaaatc caataaaaat gcagaaagag
    10201 caatgagcaa tggcgcgtaa aaaaaataag aaaaaggatg agataaatcc agatgcatgg
    10261 ctggctactt attcagatac tataacactg attcttacat tttttgtgtt attgtatgct
    10321 acatcagttg tagatatgga aaaatttaaa aatatagcaa atgcgttaaa aggtcagttt
    10381 tctggaacaa gtatgttcag tacaggttca agtacaagtg agaaatctcc aatagagagt
    10441 gttttagtgg ataaaaatga taagtcaaat ttaaaacagg atttaaaaga taaagttaat
    10501 aattctaact tacaaaatag tgtaacagtc aaagatgata gtagagggat tttactagag
    10561 ctagatgatt caattttatt tgactctggg atttctgaat taaaagcaga tagtaaagcc
    10621 actcttaata aagtatatga catgataaag atgataaaaa ataagatagt tatagaaggc
    10681 catactgata atgtacctgt aaaatcaagt acacatgaat ccaattggga tttatcttct
    10741 agtagagcag taagtgttgt aagatacttt gtagaagaaa agggcatgga ccctaagcta
    10801 ttttcagcaa caggatgtgg agagtaccaa cctttggtat caaatgaaac agcaaaggga
    10861 agagctgaga atagaagagt taatatactt ataactattg actaggagga agaggtttgt
    10921 tcaaaaataa aaaaatcatt ataattattt tgatactgat tattttctca gcaggagcag
    10981 gtttttttat attaggagaa ggtggaaata aacaaattga caagattgca ggtttgttta
    11041 ttccaacaag gaaaggtaaa gatgaagtaa agaccgaaaa tcttgactta gaagagatgg
    11101 tattgaagct agctgatgaa ggtgtaagat atttaaaagt atcaataact gtatcttatg
    11161 attcttcata taaagatata gaaaaaaata cgcctttaat tagggataat attataaatt
    11221 gttttatggc aaaaagagca gatgatttta ctgctgataa tttaaagaac ataaaagaag
    11281 aaattaaaaa tacattaaat atacaactag gtgaaaatgt aattcaaaat atatatttca
    11341 caaatatagt agtgcaataa aaggatggta agacatgata ctttatttac taaaaatatt
    11401 aatatgtatc ccaataattt taatattgat agtcttatct ttaaaaatta gccaaggaac
    11461 tttattaaaa aaatataatg ataaatatat aaaaatacta gatattgtaa atataagtaa
    11521 aaacaatagc ataataattt taaaaatagg tgaagaagga tgcattatgg catcttcttc
    11581 ctctagcatg aataaaataa aagatttgac caaagaagaa atattaaaaa tagaaaatga
    11641 cattaaagaa agaaatttta aaattcaaga ttttaaaatg gaaagaatca aaaaaaaata
    11701 tgatttcagt agatatattg gaaaatttac aaaaaaggaa gataagtaaa tggaactatt
    11761 atcaaaatta cctttggctg atgtaccata tacaagttca atgcaattgt ttttatttct
    11821 aactgcatta atgtttttac catttgtaat gtttatgatg acaagctttg tcagaatagt
    11881 tataagttta tcatttttga aatcagcatt aggagcacag caagcaattc caagccaaat
    11941 tttggtaggg cttgcaatag tattgacaat atttataatg agaccagtat taaatgagat
    12001 aaacgaaaag gcattacaac catatatgaa agaagaagtt actatggaag aagctatgaa
    12061 ggaagcagag ggacctatta aagaattttt attaaagcaa accagacaga cagatttaga
    12121 tttatttgta gaacaggctg gtttaaaaga aaagaaatta actcgtgaaa atataccact
    12181 atctgttgta gttccagcat ttgctataag tgaactaaaa actgcttttc aaataggttt
    12241 tttaatatat ataccatttt tgataataga ccttgttgtg gcaagtgttt tgatgtctat
    12301 gggtatgttt atgttacctc cagttatgat atcattacca tttaaattat tattatttgt
    12361 aatggtggat ggatggaact tgatagtaaa aacattgata ttgggatttg gataggagaa
    12421 aaatagtatg agtgaattta tgataatgag tgttcttaaa aatggcatgt ttacaggagc
    12481 tatgattgca gctccagtac tcattgtttc tcttgtagtt gggcttttaa taagtgtgtt
    12541 tcaagctaca actcaaatcc aagagcaaac tttgactttt gtaccaaaac taatagcaat
    12601 tcttttagta gtagctattg gtggaagctg gatgttacat actcttatta gctttacttc
    12661 ggagatattc aatatgatgt ctcttataac taaataagta ggatatatat gatttttgta
    12721 tttattagaa tagtggcatt ctttggaaca ctaagaatac tatttccagc tggtacacct
    12781 gctttattta agtcgctctt tgcaatcatt atatcaatat tgatttcaag tactatgcaa
    12841 attgaatatg caacaaatat agacaacatt gtattgttta ccttatatgg tataaatgag
    12901 accataactg gcattatgct tggatatata accaatctat gtttttatag tatcagaatg
    12961 gcaggttcta tgatggatca acagatggga ttatcaatga ttaatatgtt tgacccaaat
    13021 tcaatgactc agacaacttt aattgataat cttatgaact ggacagcact tatgatattt
    13081 tttagcatgg atggtcatca tgttttaatt agaggcataa ggtatagttt tgagttaatt
    13141 ccaataggga aatcattcgt agataataat atagattata taataaacat atttgtgcag
    13201 tgctttttaa ctggattcaa aatagcaata cctattgtac tttgtctgct tatggcagat
    13261 tttatattag ggcttatatc aagaagtgta cctcaactaa atgtaatgat aattggtatg
    13321 ccattaaaaa tactggttgg tattgcgtta tttatcatat caataccttt aattgtcaat
    13381 caaataagtc atttattaag tcaaatacca aagatgtatg agggaacttt tgcactagct
    13441 cctatgtttt ttatgggttc aacagataaa acagaagaag ctactccaaa gaaaaaggga
    13501 gaacaaagaa aaaaaggtaa tatagcaaag agtaaagaat tacccattgc aatgactcta
    13561 cttgcattca ctttattagt acctacatta ttttcatatg tagtggatac acttaaatct
    13621 tcgcttaatt attttttgag tctagatttt tatatgaaca taaattattc aagtatagag
    13681 aaattagtta tagcaggatt aatggatttt tttaagatat ttttaccaat agctattccc
    13741 ttcttaattt taggtatagt cgcaaaccta tttcaagtgg gaatactgtt tactggtgaa
    13801 actttaaaac ccaatttatc aaaattaaat ccagttagtg gatttaaaaa catgttttct
    13861 atgagaagtt tgtcaacctt aataaaggat acagcgatta tatctatttt ggcttacata
    13921 ggatatacat tcttccaaga taattattta gatatattaa agctaggtaa catataccta
    13981 ccaactttaa tgtacacagt taaagattta gtatattcaa tattgagtaa gatttgtgta
    14041 gctatgatag ttatagcagt tgcagattac gtttatcaaa gatacagtca taaaaagcaa
    14101 ctgagaatga caaaacaaga agttaaagat gaatataaga actcagaagg agacccagaa
    14161 ataaaagcta agataaaaca aaaacaaaga caaatttcgt ctcaaaggac aatgcaagca
    14221 gtaccaagtg ctactgtaat agtaaccaat ccaacccact tatctatagc agtgagatat
    14281 gaaaaaggga aagaccaagc tccagtagtg gtggcaaaag gtgcagatta tttagctttt
    14341 aaaataaggg aaatagcaaa gggaaatgat atacctataa tagaaaataa acctattgct
    14401 aggttgttat ataagcaagt agaaatagac caagaaattc cagaggacat gtatcaagct
    14461 tttgcagaga tattagtggc agtatataaa atcaaaaata gatacaaagt ccccaaaagg
    14521 taggataagt aatgaataag tttaatttaa aggaaaatat ggatgtaata gtggcatttg
    14581 gtgttgtagg gattgttctt atgatgatag tgccattacc tacatttata ttagatattt
    14641 tactggcaat taacataagt ttatctgtgc taattttact aatgacatta tttacaacaa
    14701 atgtacttga tttatctata tttccaacag tgttacttgt gacaacacta tttagattgg
    14761 gattaaatct ttcatcaact agattgattt taacacaggg atatgcaggt gaagttatag
    14821 aggcatttgg aagttttgtt gtaggtggaa attacgtagt aggaataatt atattcttaa
    14881 ttatattaat tgttcaattt gttgttataa ccaatggttc tggaagagta tctgaagtaa
    14941 cagctagatt tacgttagat gccatgccag gtaagcagat gagtatagat gcagatttaa
    15001 atgcaggagt tatagatgac aaaactgcta gaaaaagaag aaaagagctt caacaagaag
    15061 cagattttta tggttctatg gatggagcaa ataagtttgt aaagggagat gccatagcag
    15121 gtcttatagt aacagcaata aacataatag gtggaattgt aataggagct gtaatgctga
    15181 atatgactct tatgggtgca gcacagacat atgtaagact tactatagga gatggtcttg
    15241 taagccagat acctgctcta ttaatatcta catcagcagg tataatcgta acaagagctt
    15301 ctactgatga aaactttggt ggattagtag gtaaacagtt aacggcaata ccaaaagcag
    15361 taatgatgac tggttgtgtt ctaatcgtac ttggtatgat gcctggatta cctaaaccag
    15421 catttttttc actaggtata ggtgctatag cagcaggtta ttttttagga agagaaaaga
    15481 aagatacttt agaagacttg gagtttgaaa aacctgatat ggtaaatcca gataaaaatg
    15541 aagtagaaga tgtaacaaac ttaataaatg tagaattaat agaaatagaa attggatatg
    15601 gtttaatatc tttagctgat gaatcagcag gaggagattt acttcagagg atagcatcaa
    15661 taagaagaca atgcgcaata gacatgggga tagtcgtgca acccataaga ataagagata
    15721 acttacagtt aaatccaaac caatacaata taaaaataaa aggaaatgta gttggtgggt
    15781 atgagataat gcctaatatg gttttatgta tggaccctat gaatcaagga tttagtatat
    15841 ttggaataaa gacaattgaa cctacttttg gaatagaggc actttggata gaaagtgaca
    15901 aggtagaaga tgcagagtta aagggttata cagttgtaga ttcatccaca atacttataa
    15961 ctcacttact agatataata aaatcaaatg cacacgaatt actgggaaga caagaagtta
    16021 agactattat agatgcagca agagaaaatt atagtgctgt agtagatgaa ttgataccag
    16081 atttgatgac acttggtgaa attcaaaaag tacttaaaaa tctgttaaga gaaaaagtaa
    16141 atataaagga tagggttaca atacttgaga ctcttgcaga ccagtctaga aatacaaaag
    16201 atatagagct tcttactgaa tatgtaagaa tagccctggc tagaagcatt tgtaataatt
    16261 tagttgatga agataaggca attatagtgg ctacattgtc tccagaaact gaagagttgg
    16321 tatctaataa tttacaaagg tctgtaaatg gaacttatcc agcagttgac ccagaaaata
    16381 caaataaaat atttgagagt atacaagaag taatgaacaa tgtatatttc aatcataata
    16441 taccagtaat agtagtatca ccaaagataa gagctccatt tagaaaatta gttgaaattg
    16501 tatatcctaa tttgactgta ttatcattaa atgaaatacc taacgatatt aaaatcaaag
    16561 cagaaggtgt ggtgagcata tatgatgacg aaaaagtata cagctaacac aattcaggat
    16621 gctatgaatc tagccaaaat ggaattgggt gacaatatta cattaataga taaaaaagaa
    16681 gtaagaaagt ctggaataca aggtatcttt tcaaagaaag atattgaact aactattgga
    16741 tgggaaaaga gagaaaacgt agaacaaaaa gatttaaaac gagagataga acaattaaag
    16801 ttaattatta acaatatggg gtttgataat aagaatgata atgatataga taaaatatgt
    16861 aaaaatctac taagtttaga attaaatgaa gaaattgtag aatctataag aattgatttg
    16921 caagaaatga agttcaatgg aattgataca agcaaaaatt tagtagaaat tttaaagaaa
    16981 aagattaaaa tagaaaatca agcaataaat ggtaaaattg ctctagtcgg accaccagga
    17041 gtaggtaaaa cgactacaat agcaaagtta gccgcaaaat tagtttttga agaaaataaa
    17101 aaagtaggag taataactat agatacatac aggattggtg ctgtagaaca gttgaagata
    17161 tatactgata taatgaatat tccttttaaa ggggtaataa gtcctgatga aatggaattg
    17221 gcacttgatg agatgaaaga ttgtgatgtt gtattaatag atacaacagg tagaggctat
    17281 aaaaactcta tgcaaatact agaaatcaaa aatcttatag ataaagctga aactgataat
    17341 atacatttag ttgtgaattg tacaacaaga gaaagtgata caaaagcaat tatagattca
    17401 tatagaaatg tgaattttaa aagcttaata atcacaaagc tagatgaaac aataacatat
    17461 ggctcaatat ttaacataat gaattatgca caaaaaccaa tatcatatat tacaacagga
    17521 caaaatgttc ctgatgatat tataaaacct aatgaagata agattataag gttactatta
    17581 ggagttgaaa gtatatgata gaccaagctc aaattttgag aaaaatggca atggaaaaaa
    17641 gaggacttga tgagtttata gtagagaatg agaatgtacc taagataatt acaatagctt
    17701 ctggtaaagg cggtgttgga aagagtaatc tcgctacaaa tttgtctata tgcttgacca
    17761 aacttaataa aaaagttctt atattagatg cagacatagg aatgtctaat atagatataa
    17821 taatgggggt aaatgtaaaa gggactataa ttgatgtaat taatggcaaa aaaaatatag
    17881 aagatataat ttcacagact aagtatggtg taaatataat atctggaggt tctgccctta
    17941 atcatataga agactttaca gaagctcaaa gaaataagtt tatacatagc atagaacaga
    18001 ttcacgatgt ggattttata ataattgata caggagctgg tatgagcaaa agcctattgt
    18061 catttatata ctgtagtact gaatttttct taataacaac tccagaaccg acatcattga
    18121 ctgacgcata tagtttatta aaagctataa gtaattttgg cataaagaga agtgcaaata
    18181 taataatcaa tagggtaatt gatttagaag aagcaaaatc tacatacaaa agaataaaaa
    18241 tggttgtgga caaatttcta aaccttaatc tagaattgta tggatatata atagatgaca
    18301 aaaaagtaag tttatgtgta aaaaaacaga taccattcat tttagaatat cctacaagta
    18361 ttgcatcaaa atgtattata gccatagcaa agagaatggt aagtcagtca agagaagata
    18421 ttgttgataa taaaagtttt ctaagaaaga tgtttagtat atttaaaagc taaggaggcg
    18481 tagttaatga atagagaaga attaataaaa gagaatatgc ctcttgtaaa gagtatagca
    18541 agaaaatttt ttataccagg gaaaggtttt gaatatcaag acttagtaaa tagtggagtc
    18601 attggattga ttgatgcaat aaataaattt gatgctgaaa agggggcaaa gttttctagt
    18661 tactcttata taaaaataaa atctgctata ttagatgaaa ttagaaatca aagtccaatt
    18721 tctaaacata atctaactaa agtaaataag tataatagag tggtagaaaa gttgcaatct
    18781 aaattattaa gagagccaac ttcatatgaa attgcaaaag aattaaatgt ttcagaaaaa
    18841 gaacttcatg atatcgaaag taacatagac atgttaaata ttgtatcatt aaactatgta
    18901 atctttgaag atacaaatga aactgtacaa gatgtaataa gtgatagaga agaggaagct
    18961 ccagaaaata taatagaaga agaagaaaag ttagagattc tatctaaagc aattagtaat
    19021 ttaaatgaaa gagaaaaatt aatactttca ctgtactatt atgaagattt aaatctaaag
    19081 gagataggga aagtgctagg tgtttcagaa tcaagagttt cacaactcca cagaaaatca
    19141 ataagaaact taagaaacaa gataaaagaa cttaaatatt ctatatagat ggtgattgat
    19201 aagatgatac aaattatatt aatagtagtg tctattttaa taatagtaac tatagttata
    19261 aatttacata aggaatcaaa aaataaagat aacagatact ttgataaaat atttgagcaa
    19321 gaatatgaag caaatgatag attaataatt gcagaaaaaa gaagattctt tttagacaaa
    19381 gtacttgctg aaataagaag taataatcat ataaaagttt atgaaaatta taacctaata
    19441 aaggctaatg aagaaagaaa ggaaaacata tttatagaat caaaaaagga agtaagacaa
    19501 gaaaatgagt tatctcttaa agtgaaacat cttataagtt caggttatga tgatgtggaa
    19561 atatgtaaga tgctagatat tggaaagggg gaactgtcat taataaggag ttgttacaaa
    19621 atataaggat attattatgt gataaaaaag tattcttagg aataggtatt ggtatattaa
    19681 tatcaacttt atgcataatg ctttttagta ataatgatat gagtaaggca gagatagaaa
    19741 aaaaggccag agcgttaggc atgaaatata caagtgagat gaaagtttta gaatagatga
    19801 tactgtttag acatttacaa aaaaggaggt cataatgtga taagaggatt atatacagca
    19861 gtttctgcta tgataactaa tcaacaaaag caaaatgttg ttgtcaataa cctagctaat
    19921 atggatacaa atggatataa aagtaaacaa cttttgacta aaagttttga tgaattaaag
    19981 ttggagggtt acaataacta cgcaaatgga actaaacaaa agcagattat aggcgatata
    20041 agtccaggta tttctatgga tgaaactatc acaaatttta atcaaggacc tataaaaact
    20101 actgataata aaatggatgt agctattcaa ggtaagggat tttttctagt tagtgatgca
    20161 gctggaaatc aattttacac tagaaatggg aacttcagaa cagacaatca aggtgacctt
    20221 ataacaagtg aagggtatta tgtacttggg acgaatactg ctactggtgc tgtaggtcat
    20281 ataaatgtag gaaatcaaaa atttgaagtg gcaaaagata atacaatatc actagatgga
    20341 aatgctatgt ataaattcaa tattgtagat tttaatgact acaataactt aaaaaaagaa
    20401 ggagataact tgtattctgg aggaggagct atgaaagtaa ataatgcact tacaatacaa
    20461 agtgcgatag agtcttctaa tgtagatatg gtatctgaaa ttaataatat gatgaccata
    20521 tcaagagaat atgaggcaaa tcaaaagata attcaggcta tggattctaa attagcaaaa
    20581 atagcaagtg agattggctc agtaagatag gtgataggag gtgaattttt atgtacacaa
    20641 tgttttatac tagtaaaaca gctttatcag caaatcaaag taaactagat ataatatcta
    20701 acaatatagc aaattctgat tcaacaggat ataaaaaaat aaatatggaa tattctgatt
    20761 tagtggatga agtactaaat agaccatcat atcctacaaa tggcaatgat atatcgactg
    20821 gaacaggagc taaggcaaca gctcccatga gaatttatga acaaggtgca ttggccccta
    20881 cagatagtaa gagtaatttg gcgatagatg gagaaggatt ctttagagtg ataagaaaag
    20941 atggtacata tgcatataca agaaatggtg gatttaatat agatggttta ggtaagattg
    21001 tagatgataa tggaaatata ttagatgttc aatttgatgc aggatataac tataataata
    21061 cgaatataga tagcacaaac ttaacagttt caagaaatgg cgagttattc gtagataata
    21121 aaaaaatagg aaaaatcaat ttatatcaac ctataggaac tcaaaatttt atatctgaag
    21181 gagatagttt attcgtcgca actgatgcag cacagattaa acaagttgag aaagtagata
    21241 tagttcaagg ctatagagag aggtcaaatg tttctttaca agaagaattt gttgacttaa
    21301 tagccactca aagagcattt caaatgaact caaagggaat aaagacagca gatgaaatgt
    21361 ggcaaatagc taataattta agagctaaat aattatgtaa ggtgaggaat attcatgaat
    21421 gatatgaaag agtacgattt tggcaaacct cagagttatt caagagaaaa tttaacttgt
    21481 ttaaattttt tattagctga attttgtaaa aaatataaaa actatataat ttatgaactt
    21541 aagtgtaatt ctagtatgat tgttgatagt atagaccaag taaattatca gactttttta
    21601 gatagagtaa cttcttcatg tgtagtagta caaaatgcaa tggaacctgt tatgaaaaac
    21661 ttttctttta gaatagatag aagtgtagct gatatgtgga ttgatataac ttctggagga
    21721 actggagtta taaaggataa tgatagagag cttacagaac ttgataaaaa agtgctttta
    21781 catcttatgg atgatttagt aagaaatatg cacttatttg aaggttttga aaatatacaa
    21841 gtattggata cacatacaca tattaattta ccacaattat gttctccaac tgcaccagta
    21901 tgcgttgtag atttaaaagt gctaaatgat aatgagtata ttggaagtgt ttctctttgt
    21961 tttccgtata atggtttaga ggctctatta gaaagtatat ctgttataga attttttgat
    22021 aatgatgtag gagatgattc agaggaattt accaaaaaaa tctataatag tgtatctaat
    22081 atagaattat cagttattgc agagatagga aaagtatcaa ttaatgttga agacttactt
    22141 aaactagaag ttggagatgt aatagtaaca aataaaaaaa taaatgatta tatagatata
    22201 tttgtagaaa attcaaaatc atatacagca acaccaggat ttatatcaag caaaaaaggt
    22261 gtaaaaataa atgatgctgt tggaaaagag gtgtagttat ggacaatagt aatcttattt
    22321 cagatgaaga agcaaagatg ttattaaatg ataaagttga aagtgaagtt gatggggatg
    22381 atgagttagc cttagatgtc tctgaagtta atcgaaataa tatacaaagg atacttgacc
    22441 ttaagttaga attatctgta gttataggga gaactaagat gactctaaga gatattttaa
    22501 atttacataa aggttctctt attgaactgg atactttagc agaccaagat gtggaaatac
    22561 taatagataa taaggttttg gcttatggaa aagtagtggt ggtagattta aattttggtg
    22621 taaagataac aagtatagta agtgaagaag acatggtaaa atctcttgtt tagagataac
    22681 atcaattaat acttaaggca tgaggtggta cttattttaa acttaaatga tataaaaaaa
    22741 gatatactaa aactcaataa aaaagactca tgttctctat ataatgaatc tattaataat
    22801 ataaataata attgtatatc aactggatta aaatttttaa aacaagcaag agatttaaac
    22861 ccagatgatg ttgatatatt aaatctcaca ggtcttgtaa acttactaaa atgtaatttt
    22921 gatgatgctg tagaaagttt ctataagagt tcactttgtg aaaaaactgc tctgtgtgaa
    22981 aagtatataa acatgcttac atctgaggag tttttaattt tctttgaaaa gtacaatcaa
    23041 cttataaggt taataaataa aggaatgtat aaagaagcta tacaagggtt taaacttata
    23101 actgaccaat actgtgattt aatagaacct tatgagttgc ttgccttact gtatgacaag
    23161 gaagaagaat atataaaatt tgatgaatgt ttagaagtat tgaagattat tgataaggaa
    23221 aattatttat taaatcaaga aaataacaca ttagatatgt ataatagtgc taatatacaa
    23281 actaaaagta atgtaaaagt agatgattat aagaatgagt ttttacataa aagtagtagt
    23341 aaccataaaa ttaatgatta taataatgta actaaagaaa aaagttcaag caaaaaccag
    23401 aaaagttcag attctaataa gaaaaaaagt attaaaaaaa ataagtacct atatatagcc
    23461 ataatattag gaatattatt agtaggacaa agtatatata gttcttataa gatgaataat
    23521 ttaactgata aaatatctaa aaataatgaa actaaaaatg aagagtcaat agattctaac
    23581 ttgattaaga aagaaaataa tatagaagaa aatgaagata tgagtaaggc ttctaatata
    23641 aacaagagta ataaaaacat taataaagag gatgatgtaa aatctaaaaa aaatactgta
    23701 gaaaatgaag atgataaaga ttctgactta tttacagagg atgaattgat gtctaaggcg
    23761 aatactttaa aatcagaaaa aaaaactaaa tcttctatac aactatataa gaaagttgca
    23821 gatataggtg aaaataaagg gaatacatct gaagcaactt atcaagttgc tattctcagt
    23881 gaaaagttaa aagactataa aactgctgaa gaatattata aaatgtatgt agaaaattac
    23941 tcagaaaaag atgcttattt tgatgaatct tattataatt tagggatgat gtactataac
    24001 aatggtgatt taaaaaattc taaattgaca ttaaagaagt tagttaataa ggtaccaaat
    24061 agtatgtata ataattcaaa agtaaaagaa attttaaaag aagaatagtt aaattagata
    24121 agaaaaataa attattttat tttaaaataa tatgattata atatattgac ataccatttt
    24181 aaaaaattta aaatattaat tataaaatga ggagggataa aaaatggaat ttgaaaaagg
    24241 gagtatttca attcatacag aaaatatttt tcctataatt aaaaaatggt tatactctga
    24301 taaagacata tttataagag agcttataag taatggatgt gatgcagtaa gcaaacacaa
    24361 aagacttgta tcactaggag aaatatcaga aaataagtca tcagattata aaattacagt
    24421 atctgtaaat aaaggagaag gtacacttaa atttattgac aatggaattg gtatgactga
    24481 agaagagata aaaaaataca taaatcaagt tgctttttca ggtgctgaag atttctttaa
    24541 taaatataag gataagatgg aagagtcaaa tgacataata ggtcattttg gattaggatt
    24601 ttattctgca tttatggtgt ctaaaaaggt acaaatagat acactttcat atacagaagg
    24661 agcgactcct gtaagatgga tatctgaagg tggtacagaa tacgaaatat ctgaatcaga
    24721 tgctagaaat gatagaggaa ctactataac actatttatt gatgatgata gtaaagaatt
    24781 tttagatgaa tttactgtaa gaggaataat aaataaatac tgttctttct taccagtaga
    24841 aatatattta gaagatgttg aaagattaga aagagaagct aaagaagcag aagaaaaagc
    24901 taaaaaacaa aaggaagatg gaaaagaaga gattgtagat gcaaaagtaa ttgagccttt
    24961 aaacgacact aatcctctat ggttaaaatc tccaaaagac tgtactgatg aggagtataa
    25021 agagttttat agaaaggtat tcaatgtatt tgatgaacct ttattttgga tacatttaaa
    25081 tgtagattat cctttcaatt taaagggtat actttacttc cctaaattaa aaaatgagtt
    25141 tgaactgact gaaggaaaag taaaattata caacaatcaa gtgtttgtgg ctgacaatat
    25201 aaaagaagtt ataccagaat ttttactttt attaaaaggt gttatagact gcccagactt
    25261 accattaaat gtatcaagaa gtttcttaca aaatgacagg gatgtaagca aaatttctaa
    25321 acatataatt aaaaaagtag ctgataagtt aaaatctctt tgtaaaaatg aaagagaaga
    25381 atacaataag ttttgggatg atatacaaat atttattaaa tatggttgct taaaagatga
    25441 aagtttctat gagaaggtaa aagaatgtat actatttaaa actattgatg atgagtatat
    25501 aacattacaa gattatttag aaaaatgtaa ggacaaacat gaaaataagg tattttatgt
    25561 aagtgataag gaacagcaat ctcaatacat taaactattt aaagaatacg acttaagtgc
    25621 tgttgtttta aactcatcaa tagatactca ttttatttca tttatggaat ataaagagaa
    25681 tggagttaag tttaatagaa tagatgcaga cctttctgat gtattaaaag ataaaaatga
    25741 aaataaagat agtgaagaaa acaaagaaga gatagctaag atagaaggtt tgtttaaaga
    25801 agctgttgga gaaagagtga agaattattc tgtagaagga ttgaaaaatg aagacactcc
    25861 agctatggta ttagtatcag aacaatctat tagaatggca gaaatgcagt caagatttgc
    25921 tggaatggat ttaggaatga attttgagga agaaaaaact cttgtaataa atgagaacag
    25981 tccaataatc aaaaaattgg tttctcttaa agatgatgag gaaaagaaag ataagattac
    26041 gcttatttgt aaccagatag cagatttagc tttactttct aataaagaat taaagccaga
    26101 tgagttagat tcatttgtac aaagaagtaa taagcttatg agtcttttga tagaattata
    26161 agattgaatt tgaatacatt gaagcaaatt tataaaaagt attcaatatc agtgatgaga
    26221 aagaagtgtc tcaaaatgaa cttttcagtt catgaggcgc tttttttata tgaaattaaa
    26281 tttattttaa tcatttcaac aatgaaaaat atatttatct ctattttgag acagaccgtt
    26341 ctttattttt ttatctttgg ttaattttta aatatttaag taggttctaa taaaaaactc
    26401 tatttagtta aatatagtta acttgatata taataagata atacatataa ttaagtaaaa
    26461 gattgttttt tagtttatgt ttaaatacat aattacactt tgttaaaaac ataaaattat
    26521 tactaaagta gaaataggag gttttagcat gaattttaat tataatttgc cagtaaatat
    26581 cttatttggg agaggcagaa ttaatgatgt gggaaaagaa gtatctaaat atggcaaaaa
    26641 agtattgata gtaacaggta aaaatagtac aaagaaaact ggattacttg ataaaacaat
    26701 agatttacta aaagactcta aaatagaata tgaagttttt gatagagtag aacaaaatcc
    26761 tcttataact actatatatt caggcgtaga aattataaaa tcaactggat gtgattgtgt
    26821 tttagggctt ggtggtggaa gcattatgga tgctgccaag agtatagctt tttcttataa
    26881 aaacccagga gatttaaatg attatatatt tggaattaga caaggtgaag aagctttacc
    26941 tataatctta gttccaacaa catcaggtac aggtagtgaa ggaaattgtt ttgcagtact
    27001 tacaaattca gaaactaaag ataaaaaatc tataaagaag aatagtatgt atgcaaaagc
    27061 atcaataatt gacccagaac ttatggttac aatgccaaag catataattg catcagttgg
    27121 atttgatgca cttgcccata atatggaagc atatctttct aatggaagaa accctcttgc
    27181 agatgtacaa gctatttatg ggattgaact tatatcagaa aacctaataa aggtatataa
    27241 tgatgttaat gatttagaag catgggaaaa aataacactt gcaagtacta ttggaggaat
    27301 gacgattggt acagcgggta cagccttgcc acatggaatg gagcatcctg taagtggtct
    27361 tagagatgta atgcatggaa aaggacttgc agcgttgact cctactatta tagaaagttc
    27421 atgggatatt gatattgaaa gatttggtaa tatttcaaag gtattaggag gaacttgtgc
    27481 agaagattgt tcagatgcaa ttagaaattt ccttaaaaaa atagatttag atataaaact
    27541 aagtgattta ggtattgaaa aatcagatat agattggtta actgataatt gtatgaaaat
    27601 atcagttgca
//
LOCUS       DACTZW010000054        27547 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.054, whole genome shotgun sequence.
ACCESSION   DACTZW010000054 DACTZW010000000
VERSION     DACTZW010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27547)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27547)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27547
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.054"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            83..1483
                     /locus_tag="JAM15_12080"
     CDS             83..1483
                     /locus_tag="JAM15_12080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HAT6798991.1"
                     /translation="MNQEIFFKIMNEILENIDEGVHFVNKDGKTIIYNNSVQKMEKMN
                     RHDILANSFFDIVNKMKINRSTLLEVLEKREVIKDNIQKYLDKNGKEITAINTTIPID
                     IKGEFVGALEISKNMTTIENLLNRNYKKNLVNKVSSRQKKGYEFDDILGESNLIKEAI
                     EKSKKACKSDASVFIYGETGTGKELFSQSIHYGSNRRNYPFIAQNCAALPESLFEGIL
                     FGTSKGGFTGAIDRPGLFEQANKGTLLLDEINSMPIMLQAKLLRVLQEGYVRRVGGTK
                     DIPIDVRIIATTNESPKVILNEHKMRKDLYYRLNIIHIKIPPLRDRKEDILLLCKKFI
                     SKYNKKLNKKVVGISDEAIKILKNYDWQGNIRELENIIYCTMSMMEDEVQIETSMINL
                     NDYYNLKENKESNNYSLNDLEGKTLSKIISEIEEKYIYESLEKASYNITKAASILGMN
                     RQNLQYKIKKYNIKIL"
     gene            1739..2806
                     /locus_tag="JAM15_12085"
     CDS             1739..2806
                     /locus_tag="JAM15_12085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-binding protein"
                     /protein_id="HAT6798992.1"
                     /translation="MRKVRVGIWGFGAMGIGMANMILKKEGIEIVSVCSRSTSGKSMY
                     DVLGIERGERPEVIINKNYEEVFREKSVDVVLLATDSFTKKAFDKIIFLLNRKINVIS
                     TAEQMAYPQADDADLAKKMDEVAKENGVSILGTGINPGFVLDLLVLALSGTCEEVTSI
                     KAKRVNDLSPFGKSVMEEQGVGVTREEFIKGVEDKTIAGHVGFVESINMIADGLGWKL
                     DKIEQTKEPIMTTVDRKSKYGEALAGNVAGCRQCGYGYVNGDVLIEMEHPQQIIPEAE
                     GIKTGDYVSIKGIPNIDLQINPEIPGGVGTYAMIVNSIPLIINARPGLKTMLDIPVPR
                     AIMGDIRNQIEVELEEESKAN"
     gene            2903..3211
                     /locus_tag="JAM15_12090"
     CDS             2903..3211
                     /locus_tag="JAM15_12090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-ketopentanoate thiolase"
                     /protein_id="HAT6798993.1"
                     /translation="MDAKINDWVIIHNIVLTPEERAPQVPEDTKKVSLEMWVKGFIQS
                     DASIGDLVEVKTITGRLVKGNLLKVNPYYTHDYGKCIPELLQIGIQAKEILFGGVYNE
                     "
     gene            3204..4634
                     /locus_tag="JAM15_12095"
     CDS             3204..4634
                     /locus_tag="JAM15_12095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent lyase/thiolase"
                     /protein_id="HAT6798994.1"
                     /translation="MNNSTSMKDMSYQAVMGRNNEIMKNAIGLDYSSFEQEGIGFDYE
                     KMMSETGYTLQDIEAIQSQYAVGNTPLIELKNLTKLARKCAKEGKGAKIFVKDEAMNA
                     SGSFKARRAATAVYHAKQMGYKGVIAATSGNYGAAVASQAAMQGLKCIIVQECYDSNG
                     VGQPEIIEKARKCEAYGAEVVQLTVGPELFYTFLVLLEETGYFNASLYSPFGIAGVET
                     LGYELAIQFREKYKKDPDIVVCTNAGGGNLTGTARGLIKAGSINTKVVGASVDLKGLH
                     MASDNQFNKKSFTTGHTGFGIPYCTWPDRSDVPRSAARPLRYMDRYVLVKQGEVFYTT
                     ELLAQLEGIERGPAGNTSLAAAFSLAQELDEDKVIVVQETEYTGAGKHICPQLTFARE
                     NGIDIKFGNPREEIAGVNLILPERPELLKCVDIDMNKIRKSFIKNCISNNHIDNIDKL
                     SNRDIEFLMEEVKSSRDFVVDVLNNL"
     gene            4712..5086
                     /locus_tag="JAM15_12100"
     CDS             4712..5086
                     /locus_tag="JAM15_12100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine aminomutase"
                     /protein_id="HAT6798995.1"
                     /translation="MKKREDDFEVRRKHLQELSDDELKERFWNLATQIVEPMIELGKK
                     NTTPSIERSVLLRMGFSSLEVKPILEGVMERGLIGKGAGHVVYKLAKSKNITVREAGL
                     LLVKGEYWDEVTCLFREGVESC"
     gene            5080..7284
                     /locus_tag="JAM15_12105"
     CDS             5080..7284
                     /locus_tag="JAM15_12105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LuxR family transcriptional regulator"
                     /protein_id="HAT6798996.1"
                     /translation="MLKENKKLDIDYILKDLDKYKPKRRGWVWREHLENLEMGPFKYK
                     DCTKPLKKSVGLPSSKYFNNIDPQPSPVITTEIASGRFEDDIRRMRMAAHHGADHLMV
                     IRTAGQSHFDGLIEGTPQGIGGVPITRKQVRAQRKALDFIEEEVGRPINYHSYVSGVA
                     GPEVAVMFAEEGVNGAHQDPQYNVLYRNINMVRSFVDACEAKKIMAFANIAQIDGAHN
                     ANATAREAWKVMPELMVQHALNSIFSEKIGIDKSNICLSTVPPTAPPAPCLRIDLPYA
                     VALRELFSDYKMRAQMNTKYMESSTREATVTHVLNLLTSVLTRADIQSTITPDEGRNV
                     PWHIYNIEACDTAKQALVGMDGLMDMIELKDVGELRDKARELKERAVLYMEEISEVGG
                     YFESVEQGFFVDSGNYPERNGDGISRKIKGGVGEGTVYEREEDYLAPVTAHFGYNNVA
                     QYDENAIDNPSMLIDGCTFENPDKIIYIDELDDFDNVENRLKESYEYRNGTKIKPEME
                     WCADGIVMITMMLPTDKRTAEFAALEFVKKMNLQEIEVISREVMHESEGTRIEVKGRV
                     PFDIDLNNLVIPEEPKVLTDEEIRADIEEKPMKIVSATVGEDEHSVGLREIIDIKHGG
                     IEKYGIECHYLGTSVPVEKLVDAAIELNADAILASTIISHDDIHYKNMKKLHDYCVEK
                     GIRDKVMIACGGTQVTPEIAVEQGIDAGFGRNSKGIHVATFLVEKRREMSNK"
     gene            7284..8693
                     /locus_tag="JAM15_12110"
     CDS             7284..8693
                     /locus_tag="JAM15_12110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutL"
                     /protein_id="HAT6798997.1"
                     /translation="MENSKVSLKIDVLVAEIGSTTTVVNAFHDINTNNPIFLGQGQAP
                     TTVFEGGDVRNGLSGAIKDLANKLSVDDIEYNDMFATSSAAGGLKMTVHGLVYDMTVK
                     AAKEAALGAGAVIRQITSGRIKRTDLNKIKEINPNIILIAGGVDYGERDTAIYNAEMI
                     ASMNLGIPVIYAGNVENQEEIRLIFEDTNYKLYITENVYPKIDLLNIEPTRRIIQSVF
                     EEHITTAPGMKYIKEMVNENITPTPGAVMEASKLLYKNIGDLLTLDVGGATTDVHSVT
                     DGSDYINKILVNPEPTAKRSVEGDLGVYVNMKNIVEVIGKENLQSELYIDIDAVIENY
                     PPIPKSKEEILFVERLTKEAVVKAMLRHSGKIRNIYGTTGKVKIAEGKDLTEVRYIVG
                     TGGALTRLPSRIEILDNMLKYNKNNELLFPKEKTKILIDNDYIMASMGVLSKKYEEAS
                     LKLLLKSLNFEEERLCILG"
     gene            8678..9742
                     /locus_tag="JAM15_12115"
     CDS             8678..9742
                     /locus_tag="JAM15_12115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/ornithine racemase family PLP-dependent
                     enzyme"
                     /protein_id="HAT6798998.1"
                     /translation="MYPRLEIDIEKLKHNAKLISQMCHERSIKISFVTKSFCAQKEIV
                     EEICSEGIDHIADSRIQNLKKLQDINLPKILIRIPMLSELEEVINYCDISFNSELGTI
                     KKLNELCESKNIIHKIVLMFDLGDLREGYFYEEDFFNNVREIVRLKNIEIIGIATNLT
                     CYGAIIPSRENIGRLVSIAKRMEEKFGINLEIVSGGNSSSIHLLINNNMPEGITNLRI
                     GESILLGRETAYGENINGTYQDAFKLICQVVECKEKPSVPIGEIGVDAFRNKPVYEDK
                     GILKRAIIAIGKQDINIDSLIPIDTDIKILGASSDHMILDVSNTKYDYKLGDNLEFLL
                     TYGGIMSSSTSKYVSKKIIV"
     gene            9772..11193
                     /gene="nhaC"
                     /locus_tag="JAM15_12120"
     CDS             9772..11193
                     /gene="nhaC"
                     /locus_tag="JAM15_12120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HAT6798999.1"
                     /translation="MKERECRKASLFDAMIPITCLILFLSLGVLVYGSSPHVPLIGAA
                     AVAGLVAVYRLGFKWKELELSMFNSIKMAMQAILIIIIIGVLIGTWIVSGVVPCMIYW
                     GLKILSPNIFLVASTLVCAIVSLATGSSWSTMGTVGVALLGIGQSLGMPIGLIVGSII
                     SGAYFGDKLSPLSETTNLAPAMAGTDLFTHIKYMLYSTIPSLLICLVIYGVIGMKYSG
                     QALDIKQIELIRSTLDSTFNTLSPVLLLAPAIVIGLVVFKVPAIPGLIVGAVLGVLFA
                     VVFQGESMNTILDAAQNGYVSSTQIQEVDALLSKGGIMNMMSTVSLTICALSLGGILE
                     KTGMLEVVASSLLRLAKGVFGTVLCTMVTCTITNIIAGEQYLSIVIPGRMYNKEYKKR
                     GIHPKMLSRALEDSGTLTSPLVPWNTCGAYITATLGVSALTYGPYALLNIINPIVSLV
                     LIACKFKIARIEDEPETCLNFDV"
     gene            11622..12086
                     /locus_tag="JAM15_12125"
     CDS             11622..12086
                     /locus_tag="JAM15_12125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAT6799000.1"
                     /translation="MTRISNITIAEQSEYCFLAIRKTIDFMVEFSEFSKQSFEKISKY
                     LEERGILSSGAPIVCFHNMDLAKLDVEVGFPVATYIDGKNEILQRIVPAQKIITAIDL
                     GPYELQDPTLEDLFSWANSNGYKLHGDIYYQYLNDINRPASEYLTKMMLPII"
     gene            12384..12746
                     /locus_tag="JAM15_12130"
     CDS             12384..12746
                     /locus_tag="JAM15_12130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAT6799001.1"
                     /translation="MKIYDILTRFYIQDIEKAIPFYENLLKEKCSLRFSYKEVGLELA
                     QIGNVLLLSGSDDALKPFIETKSTFMVDSVDEWRSYLLDNGAVVVRDKKKVPTGYNMT
                     LRHPDGTIIEYVQHTKQD"
     gene            13342..14202
                     /locus_tag="JAM15_12135"
     CDS             13342..14202
                     /locus_tag="JAM15_12135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6799002.1"
                     /translation="MSYKVINVITAIDYIEEHLSEKLDLDIVANAVHYSKYHLHRTFT
                     TSVGLTMHDYIKRRKLTEAAKLLVFSKKPIIEIALIAGYESQQAFTSIFKAMYKKSPN
                     KYRKEQEFYPLQLRFVLKKDNLFSKNVLELEKEIKLASMSDIPLWMNLVRLVIDGFPN
                     LQEEEYIYQLEQYILEERALILKLNNVAIANMVFNRETRSIDFFGIHPQYRNSDIAQV
                     FLKKVIEDFLIDTDISITTFREGDKADTGHRDMIKKLGFAEAELLVEFGYPTQKFILP
                     CVEERDNRQN"
     gene            14460..16574
                     /locus_tag="JAM15_12140"
     CDS             14460..16574
                     /locus_tag="JAM15_12140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAT6799003.1"
                     /translation="MSENKQVVNCDIIASNSKHNMCEHDVELLTFFPDEIAHLIEINN
                     KLDNAFKKAENLVDKLDKDYMDAKMYMVKNRGEIDPHEMFQNEQGLKQIDNYGAFMVK
                     VRDKINKIKDSPYFARIDFRLKDMDDESKYYIGRFAFDYEDELIILDWRSPIASMFYD
                     YEIGKAGYDAPIGWVDGEITRKRQFKIKNGKLEYALESSINIQDDILQKELSHTSDEK
                     MKSIISTIQKEQNQIIRNDKADTLIIQGVAGSGKTSIALHRIAFLLYRFKDKISANNV
                     IILSPNKVFGDYISNVLPELGEEPLCELSFENIAEVQLDRVINFESEKDPLEINDAKW
                     SERVRFKSTLDFVKLIDDYIKQMPNKIFIPKDYTFGSFTAKSDWIQSRFEAYNRYPVK
                     KRLEKVAEDIHYKFESDNIMEEDLPKVKSILKSLNGMLTIKNTLTLYKDFFKQMNISN
                     MFVMAEKKTLEWSDVYPFIYIHAAYEGIQEDKIIRHIVIDEMQDYTPVQYAVINLLFK
                     CKKTILGDFGQLVNPNHTHTLDDMKQLYNDGELVMLNKSYRSTFEIINFAKKIQDISS
                     LEPIERHGEEPALLKCNNEQDEINKIKIEIEEFKKSDNATLGIILKTDNDAKAVYDAL
                     REEYSVHLISSESSSFTKGVSITSIKMSKGLEFDEVIVPSVNNKTYYSDYDRSLLYIA
                     CTRAMHKLKLTYVGTLTQLISM"
     gene            complement(16836..19079)
                     /locus_tag="JAM15_12145"
     CDS             complement(16836..19079)
                     /locus_tag="JAM15_12145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HAT6799004.1"
                     /translation="MSNIIIKGLTQNNLKNISFKIPKNKIVVFTGVSGSGKSSIVFDT
                     IAAESQRQMNETYSSFIRNRLPKYRKPQVELIDNLTASVIVDQTPLGGNARSTVGTIS
                     DLYSSLRLLFSRIGEPYIGTTSHFSFNDPNGMCKNCSGIGRVKVINIESIINPENSWN
                     TGCINDSLFKPNSWYWKQYAESGLFDLDKPIKDYSFEEYNLLLYGSKNKDGKQENPKI
                     EGIFNKYNQTYLNRDISNMSKHTKEKSERLITDKECPVCHGKRLNKETLNCNILGYSI
                     ADMCNMELTDLYDLLLQIKDKRTETVIKTLTDGLKRMIDIGLPYLHLNRESSSLSGGE
                     AQRLKLVRYMGSSLTGMTYIFDEPSAGMHPRDVHRMNQLLKKLRDRGNTVLVVEHDKD
                     VISIADEVIDIGPSAGTQGGHVVFQGSYDKLLLANTLTSNAMNLSLPIKTDSRHPKGT
                     LPIRDACINNLKHIDVDLPVGIMTVVTGVAGSGKSTLISRVFAQKYEKDVITIDQSPV
                     TATNRSMPATFLGFFDEIRKVFAKENNVEEGLFSFNSKGACPVCDGKGVLVTELVFMD
                     PIINTCEACKGTRYSEEVLSKLYKGKCIVDVLSMTVDESLKFFTEKKLCKILQTMKDV
                     GLPYMTLGQPLSTLSGGERQRIKLAKNFNKKGTIYILDEPTTGLHGSDIEKLMLIFEH
                     IVDKGNTVIIIEHNLDVLKQADWVIDIGPDGGKNGGQVVFEGTPLEMFERGCTITSDF
                     LRKSINI"
     gene            19411..20127
                     /locus_tag="JAM15_12150"
     CDS             19411..20127
                     /locus_tag="JAM15_12150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799005.1"
                     /translation="MILIVILSIFIIASINIIILGKENIRDIVIPLTLFIVSDFLFLC
                     GNIICRGGVMLLFIGLFAIPLMLIAFIWICVHMIKLYYKKDLNKRKMIGCIFSIFISI
                     GTIFIPSPSESFRFKLYEKDYSVVAKAILKVYDEKKLSSESVFYIQSDKNELEKIFSK
                     EVIKKMKKLNRNLDVVKISGNRNLVYFFFGAELQSIDGIVIFKDLKHVKPKLDFINRS
                     IQAPRLEYITNNVYYFKGEL"
     gene            20155..21093
                     /gene="blaCDD"
                     /locus_tag="JAM15_12155"
     CDS             20155..21093
                     /gene="blaCDD"
                     /locus_tag="JAM15_12155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HAT6799006.1"
                     /translation="MKRKNNFIWIVILLVVVAMGVYYVGRKHNNTKQKHDKNHINSEL
                     NKSKVENNDKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETRRSPCS
                     TFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYYKKLID
                     KVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQTMAKI
                     FEGDTNFKKEHINILRDIMKIDVNDKNINVYGKTGTGFDEKNKRVDAWFVGMLEREGD
                     TYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            21437..22120
                     /locus_tag="JAM15_12160"
     CDS             21437..22120
                     /locus_tag="JAM15_12160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6799007.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTSGKIYVEDTEISSLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            22117..24777
                     /locus_tag="JAM15_12165"
     CDS             22117..24777
                     /locus_tag="JAM15_12165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6799008.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIRLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWNSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGDRI
                     LNGKPLEPIAQKSKGESFKKISETTLTIVGKVDVSTSSVIPAYTALGYLDRTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKMS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYINSVNYHTDVPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIAVYLENSEPVE
                     SAFIEKLDNTEGVKSSLYYQKMSASTWLTEKDASKELAKNGGFKSIVSSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYCRQISVDPKLFYDTKNPTSIVYNKEEDINRSTRRNKVY
                     IDYLNLSIGDNIKLNEKVYDEDKGDYTYNMKVGAITSTLPKIVDTSSKYTLMQIVPMS
                     MVQEISKNYDEVSRLRSNRLIGVFKVNNREDIPRVREKLESIYNKDYGSGDYSIEDVL
                     ESEKQKASGIKTMNLIVGFITGLLAMIGLSNVLATVSGNIRSRRQEFAMLRSVGLSPE
                     GIKKMLVLEGLFLGITPLLLSIPVQIGIVYAFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYKQLKNENIVESIKNETI"
     gene            complement(24958..26139)
                     /locus_tag="JAM15_12170"
     CDS             complement(24958..26139)
                     /locus_tag="JAM15_12170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAT6799009.1"
                     /translation="MKTPRNINSTVVFIIFCLIITFLLSVILTTITSFNEYNVLSKAL
                     GASYEYNPKSTESILKSLKNSSDKDFKTGNEILSKHGYSKSTFWSKNFFYFLVISFGI
                     ISTMATVVYIIKHRTNKQKLSRINNLTQYLEEVNLGKESVLLRCEDEFSHLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TNQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     ESSPSVEFEIDINWTLEALLNILKNCSEHIEDGGYIVAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTLHAENCHNGGARFIIKFY
                     T"
     gene            complement(26139..26801)
                     /locus_tag="JAM15_12175"
     CDS             complement(26139..26801)
                     /locus_tag="JAM15_12175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6799010.1"
                     /translation="MAKILLLEDDDTITFGIKTSLEKKNHTVCCYNTIAEAKKNFDKT
                     IDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRTHSNTNNTITCGNISLNKVEVKAYLDNVEVLLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DS"
     gene            complement(26946..27488)
                     /locus_tag="JAM15_12180"
                     /pseudo
     CDS             complement(26946..27488)
                     /locus_tag="JAM15_12180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
BASE COUNT        10537 a         3296 c         4788 g         8926 t
ORIGIN      
        1 aaatatatga taagataaat acaatagcaa tattttatta attttttggg tttttatata
       61 tttaggtact ggggtgatat agttgaacca agagatattt tttaaaataa tgaatgaaat
      121 attggaaaat attgatgaag gggtacattt tgttaataaa gacgggaaaa ctataatcta
      181 caataattct gtacaaaaaa tggaaaaaat gaacagacac gatattttag ccaattcatt
      241 ttttgatata gtcaacaaaa tgaaaataaa caggagtaca ctattagaag ttttggaaaa
      301 aagggaagtt atcaaagaca atattcaaaa atatctggac aaaaatggaa aagagataac
      361 agcaattaat actacaatac caattgatat taaaggcgag tttgtagggg cacttgaaat
      421 atcaaagaat atgacaacga tagaaaattt actaaacaga aattataaaa aaaatttagt
      481 caataaagtt agtagtagac aaaaaaaggg ttatgaattt gatgatattt taggggaaag
      541 taatttgatt aaagaagcaa tagaaaaatc taagaaagct tgcaagtctg atgcttcagt
      601 atttatatac ggtgaaactg gaacgggtaa agagttattt agccagtcca ttcattatgg
      661 aagtaatagg agaaactatc catttatagc acaaaattgt gcggctttgc cggaatcact
      721 attcgaaggt atcctttttg gaactagcaa gggaggattt acaggagcaa tagataggcc
      781 aggcttattt gaacaagcta acaaagggac attgttattg gatgagataa attccatgcc
      841 tattatgtta caggctaaac tattaagggt tttacaagaa ggttatgtaa gaagggttgg
      901 aggaactaag gatataccta tagatgtaag aattattgca acgacaaatg aaagtccaaa
      961 ggtaatttta aacgagcata aaatgcgaaa agatttatat tataggctta acataattca
     1021 tataaaaatt cctcctctta gagatagaaa agaggacata cttctattgt gcaaaaaatt
     1081 tatttcaaag tataataaaa agttaaataa aaaagtggta ggaatttcag atgaagctat
     1141 taaaatttta aaaaattacg attggcaagg taacataaga gagctagaaa acataattta
     1201 ttgtactatg agtatgatgg aagatgaggt acaaatagaa acaagtatga ttaatctaaa
     1261 cgactattac aatcttaaag agaataaaga gagtaacaat tattctttaa acgatttgga
     1321 gggcaaaaca cttagtaaga ttatcagtga gatagaagaa aagtatatat atgaatcatt
     1381 agaaaaggca tcgtacaata taactaaagc tgcatcaatt ttaggtatga ataggcaaaa
     1441 tttacagtat aaaataaaaa aatataatat caaaatatta taaataagca agataaaaaa
     1501 acaaaataga agtaaaataa aaaagcaaaa tataggagca aaattattat aaaagagcaa
     1561 aatattttgc tctttttttt atttctcata agaaatatta ttttttattt atgaaaatac
     1621 ataataaaat aattatagtt tcaacgttcc aataaatatt tactttaatt ttaaagttgg
     1681 cacgatttat gctttaacta attattgaga atatataaat ttttaggagg gtgtatatat
     1741 gagaaaagta agagtaggaa tatggggatt tggagctatg ggaataggta tggctaatat
     1801 gattctaaag aaagaaggta tagaaatagt atctgtttgt agtagaagta cttcagggaa
     1861 aagtatgtat gatgttttag gaattgaaag aggagaaaga ccagaagtta ttatcaataa
     1921 aaattatgaa gaagttttta gagaaaaaag tgtagatgtt gttttgttag caactgattc
     1981 atttactaaa aaggcttttg ataaaataat tttcttatta aatagaaaaa taaatgttat
     2041 atcaacagca gaacaaatgg catatccaca agctgatgat gcagatttag ctaaaaaaat
     2101 ggatgaagtt gcaaaggaaa atggagtaag tatacttgga acaggaataa atccaggatt
     2161 tgtattagat ttactagtat tggcactttc aggtacttgt gaagaagtta ctagtataaa
     2221 agctaagaga gtaaatgatt tatctccatt tggaaaatct gttatggagg aacaaggtgt
     2281 tggagtaaca agggaagaat ttataaaagg tgtagaagat aagactatag caggtcatgt
     2341 aggttttgta gaatcaataa atatgatagc tgatggatta ggttggaaat tagataagat
     2401 agaacaaaca aaagagccaa taatgactac agtagataga aaatctaaat acggagaggc
     2461 attggctgga aatgttgctg gttgtagaca atgtggatat ggatatgtaa atggagacgt
     2521 tttaattgaa atggagcatc cacaacagat aataccagaa gcagaaggta ttaaaacagg
     2581 agactatgta tcaataaaag gtataccaaa cattgattta caaataaatc ctgaaatacc
     2641 tggaggagta ggtacttatg caatgatagt aaactctatt ccattaataa taaatgctag
     2701 accaggtctt aaaactatgt tggatatacc agtgcctaga gcaataatgg gagacataag
     2761 aaatcagata gaagttgaat tggaagaaga atcaaaggct aattagtaag ataacagtta
     2821 gctaattggt aaaataatgt ttaatttaaa ataacagtaa attaattagt aaggaatagt
     2881 caattaataa ggggatgaaa aaatggatgc taaaattaat gattgggtta ttatacacaa
     2941 tatagtattg actccagaag aaagagctcc acaagttcca gaggatacta agaaagtatc
     3001 cttagaaatg tgggttaaag gttttataca aagtgatgct tctataggcg acttagtaga
     3061 agttaaaaca attacaggta gacttgtaaa aggtaattta cttaaagtaa atccatatta
     3121 tactcatgat tatggtaaat gtataccaga gttactccaa ataggaatcc aagctaaaga
     3181 aatattattt ggaggtgtat ataatgaata attcaacatc aatgaaagat atgagttatc
     3241 aagctgttat gggaagaaat aacgaaataa tgaaaaatgc aatcggattg gattattctt
     3301 cttttgaaca agagggaata gggtttgatt atgagaaaat gatgagtgaa acaggatata
     3361 cattacaaga tattgaagca attcaatcac agtatgctgt tggaaatact cctctaatag
     3421 agcttaaaaa tttgactaaa ttagctagaa aatgtgctaa agaaggtaaa ggagctaaaa
     3481 tatttgtaaa agatgaagca atgaatgcat ctggtagttt taaagcaaga agagcagcta
     3541 ctgcagtata tcatgccaaa caaatgggat ataaaggtgt aatagcagct accagtggta
     3601 actatggtgc agctgtagca tcacaagcgg caatgcaggg attaaaatgt ataatagttc
     3661 aagaatgtta tgattctaat ggtgtaggtc aacctgaaat tatagaaaaa gcacgaaaat
     3721 gtgaggcata tggagcagaa gttgttcagt taactgttgg accagagtta ttttatacgt
     3781 tcttagtttt attagaagaa acaggctatt ttaacgcatc attatattca ccatttggaa
     3841 ttgcaggtgt agaaacttta ggttatgagt tagctatcca atttagagaa aagtataaaa
     3901 aagaccctga tatagttgtt tgtacaaatg caggtggtgg taatcttact ggaactgcaa
     3961 gaggattgat aaaagctggt tccattaata ctaaagtagt aggagcaagt gtagatttaa
     4021 aaggattaca catggctagt gataatcaat ttaataaaaa atcatttaca acaggacata
     4081 caggttttgg gataccatac tgtacatggc ctgataggtc agatgtacct aggtctgcag
     4141 ctagaccact tagatatatg gatagatatg tattagtaaa acaaggagaa gttttttata
     4201 caactgaatt attggcacag ctagaaggta tagaaagagg tccagcagga aatacatctt
     4261 tagcagcagc attctcttta gctcaagagt tagatgagga taaagttata gtggtacaag
     4321 aaacagaata tacaggcgca ggtaaacata tatgtccaca gcttactttt gcaagagaaa
     4381 atggaataga tataaaattt ggaaatccaa gagaagaaat tgcaggagta aacttaatat
     4441 taccagaaag accagaatta ttgaaatgtg ttgatattga tatgaataaa ataagaaagt
     4501 catttataaa aaattgcata tctaataatc acattgataa tattgataag ctaagtaatc
     4561 gagatataga atttttaatg gaagaagtaa aaagttcaag agattttgtt gttgatgtat
     4621 taaataattt atagtaatta ttgttttttt atttaatata aaataaaaat tcagaaaatt
     4681 ctattaaatc aatgcgaatg gaggaatgtt catgaaaaaa agagaggatg attttgaagt
     4741 tagaagaaaa catcttcaag aactgagtga tgatgagtta aaagaaaggt tttggaattt
     4801 agctacccag atagtagaac caatgataga acttggtaaa aagaatacaa caccatcaat
     4861 agaaaggtct gtcttgttaa gaatgggatt ttcttctctt gaagtaaaac ctattttaga
     4921 aggggttatg gaaagaggtc ttataggtaa aggagcaggg catgtagttt ataaattggc
     4981 taaatctaaa aatataacgg ttagagaagc aggtttgtta ttagttaagg gtgaatattg
     5041 ggatgaagtt acatgtttat ttagagaagg ggtagaatca tgttaaagga aaataaaaaa
     5101 ttggatatag actatatatt aaaagatttg gataaatata aaccaaaacg aagaggttgg
     5161 gtttggagag aacacttgga aaatcttgaa atgggacctt ttaaatataa agactgtaca
     5221 aaacctttaa agaagagtgt agggctacca tcatctaagt atttcaataa tatagaccct
     5281 caaccaagtc cagttattac tactgaaata gcttctggta gatttgagga tgatataaga
     5341 agaatgagaa tggcagctca tcatggagct gaccatctaa tggttatcag aactgctgga
     5401 caatcacatt ttgatgggct tatagaagga actccacaag gtataggtgg agttccaata
     5461 acaagaaaac aagtaagagc tcaaaggaag gctcttgatt ttatagaaga agaagttggt
     5521 agacctatta attaccattc atatgtaagt ggtgttgctg gtcctgaagt agcagtaatg
     5581 tttgctgagg aaggagtcaa tggagcacat caagacccac aatataatgt tctgtatagg
     5641 aatataaaca tggtaaggtc ttttgtagat gcttgtgagg caaagaaaat aatggctttt
     5701 gccaatatag ctcaaattga tggagcacat aatgctaatg ctactgctag agaagcatgg
     5761 aaggtaatgc ctgaacttat ggttcaacac gctttaaact ctatattctc agaaaaaata
     5821 ggtatagata aaagtaatat atgcttatca acagttccac caacagcacc tccagcacca
     5881 tgtttaagaa tagacttacc ttacgctgtt gcacttagag aattatttag tgattataag
     5941 atgagagctc aaatgaatac taaatatatg gaatcatcaa ctagagaagc aacagttact
     6001 catgtattaa acttattaac atcagtatta actagagctg acatacaatc aactataaca
     6061 cctgatgaag gtagaaatgt accttggcat atatacaata tagaagcatg tgatacagca
     6121 aagcaagctt tagttggtat ggatgggctt atggatatga tagaacttaa agatgtcggt
     6181 gaattaagag acaaagcaag agaacttaaa gaaagagctg tattatatat ggaagaaata
     6241 tctgaagttg gtggatattt tgaatctgtg gaacaaggat tttttgttga ttctggaaat
     6301 tatccagaaa gaaatggtga tggaatatct agaaaaataa aaggtggagt tggtgaaggt
     6361 actgtttatg aaagagaaga agattattta gcacctgtaa ctgctcactt tggatacaat
     6421 aatgtagctc aatatgatga aaatgctata gataatccat caatgttaat agatggatgt
     6481 acatttgaaa atccagacaa aataatatat attgatgagc ttgacgattt tgataatgta
     6541 gaaaatagac taaaagaatc atatgagtac agaaatggaa ctaaaattaa gcctgaaatg
     6601 gaatggtgtg cagatggaat tgtaatgata acaatgatgc ttcctactga taaaagaaca
     6661 gcagagtttg cagctttgga atttgtcaaa aaaatgaact tacaagaaat tgaggtcata
     6721 agtagagaag ttatgcatga atctgaaggg actagaatag aagtgaaagg aagagttccg
     6781 tttgatatag atttaaacaa tttagtaata ccagaagaac ctaaggtact aactgatgaa
     6841 gaaataagag cagatataga agaaaaacct atgaaaatag tttcagctac ggttggagaa
     6901 gatgaacatt cagttggttt aagagaaata atagatataa aacatggagg tattgaaaaa
     6961 tatggcatag aatgccacta tctagggact tctgtacctg tagaaaaatt ggtagatgca
     7021 gcgattgaac tgaatgcaga tgcaatactt gcatctacaa taataagtca tgatgatatt
     7081 cactataaaa acatgaaaaa attacacgat tattgtgtag aaaaaggtat aagagataaa
     7141 gtaatgattg cgtgtggagg aacacaagta acacctgaaa tagctgttga acaaggcatc
     7201 gatgctggat ttggaagaaa cagcaaaggc atacatgtag ccactttctt agttgaaaaa
     7261 agaagagaaa tgagtaataa ataatggaaa atagcaaagt ttctttaaaa atagatgtgt
     7321 tggtagctga aattggaagt actactacag tggtaaacgc tttccacgat attaatacta
     7381 acaatcctat atttttgggt caaggtcaag ctccaacaac agtgtttgaa ggtggcgatg
     7441 taagaaatgg cttatcaggt gctattaaag atttagctaa taaattatct gtagatgata
     7501 tagagtataa tgatatgttt gcaacttcta gtgcagctgg tggattaaaa atgactgttc
     7561 atggattagt ctatgatatg acagtaaaag cagctaaaga agcagcttta ggggctggag
     7621 ctgttattcg tcaaataaca tcaggtagaa ttaaaagaac tgatttaaat aaaataaaag
     7681 aaataaaccc aaacataatt ttaatagctg gtggagtcga ttatggagaa agagatacag
     7741 ctatttataa tgcagaaatg atagcttcta tgaatctagg cataccagtt atatatgctg
     7801 gtaatgttga aaatcaagag gaaataaggt taatatttga agatactaat tataagcttt
     7861 atataactga aaatgtatac cctaaaatag atttattgaa tatagaacct acaagaagaa
     7921 tcattcaaag tgtatttgaa gaacacataa ctacagcacc aggaatgaaa tacattaaag
     7981 aaatggttaa tgaaaatatt actccaaccc caggagctgt aatggaagct tctaaacttt
     8041 tatataaaaa tattggagat ttattaactt tggatgtagg tggagcaact actgatgtac
     8101 attctgttac agatggaagt gactatatta ataaaatttt ggttaatcct gaacctactg
     8161 caaagagaag tgttgagggg gatttaggtg tatatgtaaa tatgaagaat atagtagaag
     8221 ttataggtaa agaaaactta caaagtgaac tatatataga tattgatgca gtaatagaga
     8281 attatcctcc aataccaaaa tcaaaagaag aaatattatt tgttgagagg ttgacaaaag
     8341 aagctgttgt taaagctatg ctaagacatt caggaaaaat aagaaatatc tatggaacaa
     8401 ctggaaaagt caaaattgca gaagggaaag atttaacaga agtaagatat atagttggta
     8461 cagggggagc acttactagg ctccctagta gaattgaaat attagataat atgctcaaat
     8521 acaataaaaa taatgaatta ctatttccaa aggaaaaaac aaagatatta atagataatg
     8581 actatattat ggcatctatg ggtgttttat ctaaaaaata tgaagaagca tctcttaagc
     8641 tcctgttaaa aagtttgaat tttgaggagg aaagattatg tatcctaggt tagaaataga
     8701 tatagaaaag ttaaagcata atgcaaaatt aatttcgcag atgtgtcatg aaagaagtat
     8761 taagatatct tttgttacta aatcattttg tgcacaaaaa gaaatagtag aagaaatatg
     8821 tagtgaagga atagaccata tagcagattc aagaatacaa aacttaaaaa aattacaaga
     8881 tataaatcta cctaagatat tgattagaat cccaatgtta agtgaattag aagaagttat
     8941 caattattgc gatattagtt ttaactcaga attaggaaca ataaagaaat taaatgaatt
     9001 atgtgaaagt aaaaatatta ttcataagat agttcttatg tttgacttag gagatttacg
     9061 agaaggatac ttttatgaag aagacttttt taataatgta agggagatag taagattaaa
     9121 aaatattgaa ataattggta tagctacaaa cttaacctgt tatggagcta ttataccatc
     9181 tagggaaaat ataggcagac tggtaagtat agcaaaaaga atggaagaaa aatttggaat
     9241 aaatctagaa atagtatctg gaggtaattc aagttcgatt catctgttga taaataataa
     9301 tatgccagaa ggtattacta atttgagaat aggcgagtcc attctacttg gtagagaaac
     9361 ggcatacggt gaaaatataa atggaacata tcaagatgca tttaaattaa tatgccaagt
     9421 agttgaatgt aaagaaaaac catcagttcc tattggagaa ataggagttg atgcctttag
     9481 aaataaacct gtttatgaag ataagggaat cttaaaaagg gcaatcatag ctataggtaa
     9541 acaagatata aatattgact ctttaattcc aatagacact gatataaaaa tattaggggc
     9601 aagttcagac cacatgatac tagatgtaag taacacaaaa tatgattata aattaggtga
     9661 caatttagaa tttttattaa cttatggggg tatcatgtca tctagtacga gcaaatatgt
     9721 ttcaaaaaaa attatagtgt agtgtttaaa taattaggag gaaactattt tatgaaagag
     9781 cgagaatgta gaaaagcaag tctgtttgat gcaatgatac caattacttg tttgatatta
     9841 tttttaagtc taggagtatt agtgtatggt tcatcacctc atgtaccact aataggagca
     9901 gcagcagtag caggacttgt ggctgtatat agacttggat ttaaatggaa agagttagaa
     9961 ttaagtatgt ttaatagtat aaagatggca atgcaagcaa tcttaatcat aattataata
    10021 ggcgtactta taggaacttg gatagtaagt ggagtagttc catgtatgat ttactgggga
    10081 ctaaaaattt tatcaccaaa tattttttta gtagcatcaa cattagtctg tgcaatagta
    10141 tctcttgcga caggttcatc ttggagcaca atgggtacag taggagtagc tcttttagga
    10201 attggtcaaa gtttaggtat gccaattgga ttaatcgtag gttctataat atctggagct
    10261 tactttggag ataaactatc acctttatct gaaacgacta acttagctcc agcaatggca
    10321 ggaacagatt tgtttacaca tataaaatat atgttatatt cgactatacc atcattatta
    10381 atttgtttag taatttatgg tgtaattgga atgaagtatt caggtcaagc actagatata
    10441 aaacaaatag aattaattag gtctacatta gattctacat ttaatacttt atcaccagta
    10501 ttattattag ctccagcaat agtaattgga ttagttgtat ttaaagttcc tgctatacca
    10561 gggcttatag taggtgctgt attgggagta ttgtttgcag tagtttttca aggagaatct
    10621 atgaatacga tattagatgc agcacaaaat ggatatgttt cgtcaacaca aatacaggag
    10681 gtagatgctt tattatctaa aggtgggatt atgaatatga tgtccactgt atccttaaca
    10741 atatgcgctt tatctcttgg aggtatttta gaaaaaacag gtatgcttga agtagtagca
    10801 tcttctttac taagattagc aaagggtgta tttggaacag tattatgtac tatggtaact
    10861 tgtacaatta ccaatataat agcaggtgaa caatatctat ctatagttat accaggaaga
    10921 atgtataata aggaatataa aaagagaggt atacatccta agatgttgtc gagagcttta
    10981 gaagatagcg gaactttaac ttctccatta gtaccatgga atacatgcgg ggcgtatata
    11041 acagcaacat taggtgtatc tgcactaaca tatggtccat acgctttatt aaatattata
    11101 aatccaatag tatctttagt attaattgca tgtaagttta aaatagcaag aatagaagat
    11161 gaacctgaaa cttgtttaaa ttttgatgtt tgataataga taacttatgt aagaacgtag
    11221 gaactagggg ggtagcctgt ggggaattag taagacatat tttagtgtgc gaaattctat
    11281 aaatcagtaa tcttgtgact ttagccatgg gaggttcaga ttagtaaatt tatagtttta
    11341 tattagtcta tattttgatc ttttaattgt ttgtataaat tttttataga aaaagatttc
    11401 ttttagactt gcctaaaaat taggcaagtc ttttaagtat gttctgatta taagagcact
    11461 gtgtgacaag aatgatgaga ttatttttgc tatactttcg atataagaaa tggaaggagg
    11521 ttatgtttta tatttatatg aaataattag ttacacagtg aattttcgta taatttggta
    11581 taaaaagatt agaaatgaaa ataaagtaat ggaggaataa aatgactaga atatccaata
    11641 taacaatagc tgaacaatct gagtactgtt ttttggcaat acgaaaaaca attgacttta
    11701 tggtagagtt ttcagagttt tcaaaacaaa gttttgaaaa aatttctaaa tatctggagg
    11761 agagaggaat tttatcttca ggagcaccga ttgtatgttt tcataacatg gatttagcaa
    11821 aattggatgt tgaagtaggg tttcctgtag ccacttatat agatgggaaa aatgagattc
    11881 tacaaaggat tgttcctgca cagaaaataa taactgcaat tgatttagga ccttatgaat
    11941 tacaagaccc tactttagaa gacttatttt catgggcaaa tagcaatgga tataaacttc
    12001 atggcgatat atattaccag tatttaaatg atatcaatcg tccagctagt gaatatctta
    12061 cgaaaatgat gttacccatt atatagaaag ttaaagatta tcgtttgtta gttgataatt
    12121 agaagaacat ttaatgctac tgcataaatt ttatcctaaa taatatcaag gtgatttaat
    12181 ttatgtattc taatgtaact gtagataatc aatttataac taacttagtg taatttagat
    12241 ttaatttatt attctaatgt aaccccaata tattgttaag gtctacttaa gatgctcaaa
    12301 aggctatgct taatttattg ttatataatt tgtagagtgg tataatttag aagtgatact
    12361 atatagatat atagggggaa aatatgaaaa tatatgatat attaacacgt ttttatattc
    12421 aagatataga aaaagccata cctttttatg agaatctttt aaaagaaaaa tgttctttgc
    12481 gtttttctta taaagaagtt gggttggaat tagcgcaaat aggaaatgtt ttactattat
    12541 ctggttctga tgatgctctt aaaccattta tagaaacaaa atctactttt atggttgatt
    12601 ctgttgatga atggagaagt tatctattgg ataatggagc agttgtagta agagataaga
    12661 aaaaagttcc tacaggatat aatatgacat tgagacatcc agatggtaca attatagaat
    12721 atgttcaaca tacaaagcag gattagttaa aaatagattt tactactgag caactaatta
    12781 gaatctattc ttagacgtac aatttattat ttttggtatt aatagattat aagtcaaatt
    12841 ataatatttc aaaatagaat agaaatttat ttacataaaa gagagtgttt aaaaatgaac
    12901 tttttagttc atgaagcact cttttttgta tgaaatcaaa tacatcaata tataaaataa
    12961 actgatgaag agcttaaatt aaaataaaaa gattcataac aggaccccat taaactttaa
    13021 gatagggtaa gtttgtaatc ataattaaat aattgtaaaa agctgttttt agtcgtataa
    13081 tataaatatt tatcatttaa ttaaggaatc taaaaggaat ctaataagaa gaaaataata
    13141 aataactttt tagatttact aaatgaaaaa ttattgaaaa ttaaaggatt agagtcttta
    13201 atcagaaagt aaaaagtaat atattaaatt tatgaattga aaacttaaac aacaaatttg
    13261 tttataaaat agcaagattc attaaatata actaagtaat aattgatata atgttgcatg
    13321 gataaaagga gggaagctgc aatgtcttac aaagtaatta atgtcataac tgctattgac
    13381 tatatagagg agcatttatc agaaaagctg gatttagata tagttgctaa tgctgttcat
    13441 tactcaaaat atcacctgca tagaactttc acaacttctg ttggcctaac aatgcatgat
    13501 tacataaagc ggagaaagtt gacagaagca gcaaaattat tggtattttc aaagaaacca
    13561 attattgaaa ttgcattgat agctggatat gaaagtcaac aggcattcac ttctatattt
    13621 aaagctatgt ataaaaaatc tccaaataaa tataggaaag aacaagaatt ttatcctttg
    13681 cagctaagat ttgttttgaa aaaagataac ctattttcaa agaatgtact agagttggaa
    13741 aaagaaatta aacttgcaag tatgtctgac ataccattat ggatgaattt agtgagatta
    13801 gtcatagatg gatttccaaa tttgcaagag gaagaatata tatatcaatt agaacagtat
    13861 attttagaag aaagagcttt aatattaaaa cttaataatg tcgctattgc aaatatggtg
    13921 tttaatagag aaactagaag tattgatttt tttggaatac atccacagta tcgtaattca
    13981 gacattgcac aagtgttttt gaagaaagtt attgaagatt tcttgataga tacagatatc
    14041 tcaattacta cctttcgaga gggtgacaaa gctgatacag gacatagaga tatgataaag
    14101 aagttggggt ttgcagaagc agagttgctt gtggaatttg gatatcctac tcaaaaattt
    14161 attcttcctt gtgtagaaga aagagataat agacaaaatt aattgtagat taaatgcaaa
    14221 gtttaccaca tattttttgt ttgaattatt ttatatataa gagtatttct gcttttaatg
    14281 tattttgctt gtaagtgtac ttatggtaat aaatatagaa agatttagtt ttttaaaaaa
    14341 agaactttaa agctaaaaag ctaacattta agttaaatag caagaatgat taaaaactcc
    14401 aaaacacaat taagtataat gattcagtgt aagtacttaa ttaacaaagg aggatttaaa
    14461 tgtctgaaaa taaacaagta gtaaattgcg atattattgc atccaattct aaacataata
    14521 tgtgtgaaca tgatgtagag ttattaactt tttttccaga tgagattgca catctaatag
    14581 agataaataa caagctagac aatgctttta agaaagctga aaatcttgtt gacaagcttg
    14641 ataaggatta tatggacgct aaaatgtata tggtaaaaaa tcgtggtgaa atagacccac
    14701 atgaaatgtt tcaaaatgaa caaggactaa aacaaataga taactatggg gcttttatgg
    14761 taaaagttcg agataagatt aataaaatca aagattctcc atactttgct agaatagatt
    14821 ttaggctgaa agatatggat gatgaatcta agtattatat tggtagattt gcatttgatt
    14881 atgaagatga gcttataata cttgactggc gttctccaat tgccagtatg ttttatgatt
    14941 atgaaatcgg aaaagctgga tatgatgctc caataggatg ggtggatgga gaaataacaa
    15001 gaaaacgaca atttaaaatt aaaaatggaa aattggaata tgcactagaa agttccatta
    15061 atatacaaga tgatattctt caaaaagaac ttagtcacac ttcagatgaa aaaatgaagt
    15121 caatcatttc aacaatacaa aaggaacaaa atcaaattat tagaaatgat aaagctgata
    15181 cactgattat tcaaggggta gctggttctg ggaaaacatc tatagcatta cacagaattg
    15241 cttttcttct ttatcgattt aaagataaaa tatcagcaaa taatgtaatt atcctatcac
    15301 ctaataaagt ctttggagac tatatttcca atgtccttcc tgagcttgga gaagaaccat
    15361 tatgtgaatt aagttttgaa aatatagcag aggtacaatt agatagagtt attaattttg
    15421 aaagtgagaa agacccatta gaaataaatg atgctaaatg gtctgaaaga gtgcgtttta
    15481 aatctacact tgattttgta aaacttattg atgattatat aaaacaaatg ccaaataaga
    15541 tttttattcc aaaagactac acttttggaa gttttacagc taaaagtgac tggatacaga
    15601 gtagatttga ggcatataac agatatccag ttaagaagag attagaaaag gtagctgaag
    15661 acattcatta taaatttgaa tcagataata ttatggaaga agatttacca aaggtaaaaa
    15721 gtatacttaa aagtttgaat ggaatgttga caataaaaaa tactcttaca ctatataagg
    15781 atttctttaa acaaatgaat atatcaaaca tgtttgtgat ggcagaaaag aaaacacttg
    15841 aatggtcaga tgtataccca tttatatata ttcatgctgc atatgaaggt atacaagaag
    15901 ataagattat aaggcatatt gttattgatg aaatgcagga ttatacacct gttcaatatg
    15961 ctgtaataaa cttacttttt aagtgtaaaa agactattct tggagatttt ggacaattgg
    16021 ttaatcctaa tcatactcat acattagatg atatgaaaca gctatataat gatggggaac
    16081 tagttatgtt gaacaagagt taccgttcta cttttgagat tattaatttc gccaaaaaga
    16141 ttcaagatat atcttcatta gagcctattg aacgacatgg tgaagaaccg gctttattaa
    16201 aatgtaataa cgagcaagat gaaataaata agataaaaat agaaattgaa gaatttaaaa
    16261 agagtgataa tgcgactctt ggtattatat taaagacaga taatgacgct aaagctgtat
    16321 atgatgcgtt aagagaagaa tatagtgttc acttaatatc ttctgaaagt tctagcttta
    16381 caaaaggagt atccataact tctattaaaa tgtcaaaagg tttagagttt gatgaagtta
    16441 ttgtaccttc agtaaataat aaaacatatt atagtgatta tgaccgcagt ttgttatata
    16501 ttgcttgtac acgagctatg cacaaactta agttaacata tgttggtaca ttaactcaac
    16561 ttataagcat gtagattata tcttatatgc atttattatc gtaaatataa attgggacaa
    16621 agattcatca ataaatcaac aaaaaataat acttataaat ttataaaaaa tgaaagctat
    16681 aaattacatt tgaaatttta taaaattttg tgatttatag cttttataat attaatttct
    16741 tttaaaataa agttaaactt taaatttatg aaataaaaca aagtagtaat atatatgtaa
    16801 tagttcttaa tttcttaata ttagtattat attatctata tatttattga ttttctaagg
    16861 aaatctgatg ttatagtgca acctctttca aacatttcta gtggtgtacc ttcaaatacg
    16921 acctgaccac cgtttttgcc accatcagga ccaatatcaa ttacccagtc tgcttgtttc
    16981 aatacatcca aattatgttc aattataatt acagtattac ctttatcaac tatatgctca
    17041 aaaatcaaca taagcttttc aatatcagaa ccatgaagcc ctgtagttgg ctcatctaaa
    17101 atatatatag tacctttttt gttgaagttt ttagctaact taattcgttg acgttctcct
    17161 ccagatagtg tgctaagtgg ttgacctaag gtcatataag gtaaaccaac atctttcatt
    17221 gtttgtaaga ttttacatag cttcttttct gtaaaaaatt taagagattc atccactgtc
    17281 atagatagta catcaactat acatttacct ttatataatt ttgacaaaac ttcttcacta
    17341 tatctagtac ctttgcaagc ttcacatgta ttaataatag ggtccatgaa tacaagctct
    17401 gtaacaagta ctcctttacc atcacaaaca ggacaagctc cctttgaatt aaagctgaat
    17461 aaaccttctt caacattatt ttctttagca aatacttttc ttatctcatc aaagaaacca
    17521 agaaatgtag caggcataga acgatttgta gctgtaactg ggctttggtc gattgtaata
    17581 acatcttttt cgtatttttg tgcaaaaaca cgagagatta aagtactctt gccagaacct
    17641 gctactccag taacgacagt cataattcca actggtaaat ctacatcaat atgttttaga
    17701 ttatttatgc aagcatctct aattggaagg gtaccttttg gatgacgaga gtcagttttt
    17761 ataggtaatg atagattcat tgcatttgaa gtaagagtgt ttgctaaaag taatttatca
    17821 taagagcctt ggaatacaac atgtccaccc tgagtaccag cacttgggcc aatatctata
    17881 acttcatctg ctatggagat aacatcttta tcatgctcta ctacaaggac agtatttcct
    17941 ctatctctaa gtttttttaa tagctgattc atacgatgta catctcgtgg atgcatacca
    18001 gcactaggtt catcgaaaat ataagtcata cctgtgagac tgctccccat atagcgtaca
    18061 agttttaatc tttgagcttc tcctccagat agagatgatg attctctatt tagatgtagg
    18121 taagggagac caatatcaat cattcttttt aaaccatcag taagagtctt tattacagtt
    18181 tcagttcttt tatcttttat ttgtaacaat aaatcataaa ggtcagtaag ttccatattg
    18241 cacatatctg caatcgaata tcctaaaata ttacagttaa gagtttcttt atttaatctt
    18301 tttccatgac atacaggaca ttccttatct gttataagtc tttctgattt ttcttttgtg
    18361 tgtttgctca tattgctaat atctcgattt agatatgttt gattgtattt gttaaaaata
    18421 ccctctattt ttggattttc ttgttttcca tctttatttt ttgaaccata aagcaataaa
    18481 ttatattctt caaaagaata atcttttata ggtttatcta aatcaaaaag tccagactct
    18541 gcatactgct tccagtacca tgaattaggt ttaaataaag agtcatttat acatcctgta
    18601 ttccatgaat tttcaggatt tataatagat tcaatattga ttactttaac cctaccaatc
    18661 ccagaacaat ttttacacat accatttggg tcattaaaag aaaaatgtga agttgttcct
    18721 atgtagggtt ctccaattct agaaaataat aatcttaatg atgaatacaa atcacttata
    18781 gtaccaactg tagaacgtgc attgccacca agaggagttt ggtctacgat tacagaagca
    18841 gttaaattat caatcagctc tacctgaggt tttctatatt taggtagcct atttctgata
    18901 aatgaagaat atgtttcatt catctgcctt tgtgattctg ctgcaattgt atcaaatacg
    18961 atactggatt ttccagaacc agaaactcca gtaaaaacaa caattttatt tttaggaatt
    19021 ttaaatgata tattttttag gttattttgt gtaagtcctt ttattataat atttgacatg
    19081 aatgttaaat cctttctgag tacattttag taaagcaatt atattatgta accatattat
    19141 aataaaatta aaatctactt tcttgatata ttctgctatg ttatagaagg tatttctaaa
    19201 tttaaccaat cccatacaat ctgaataaat gatagttgat aatagataaa aaagtatata
    19261 atagatactc gtaatttgat aagtacaaag ataattatac aattaaaacg acttgacatc
    19321 taaaacttac tattgtaata tttaaatatt acaatagtaa gttttaaata aagaataaat
    19381 aattacctca caaactgaaa ggaggacata atgatactaa tagttatatt gagtatattc
    19441 atcatagcct caatcaacat aattatatta ggtaaagaaa atataagaga tatagttatc
    19501 cctttaactc tatttattgt aagtgatttt ttatttttgt gtggaaatat aatatgtagg
    19561 ggaggagtaa tgctactatt tataggttta tttgcaatac cattgatgct aattgcattt
    19621 atatggattt gtgtacatat gattaagctt tactataaaa aagatttaaa taaaagaaaa
    19681 atgattggat gtatatttag tatctttata agtataggta ctatatttat tcctagtcca
    19741 agtgaaagtt ttagatttaa actttatgaa aaagattata gtgtagtagc taaagctatt
    19801 ttgaaagttt atgatgaaaa aaagttaagc tctgaatctg tcttttatat tcaatctgat
    19861 aaaaatgaat tggagaagat attttctaaa gaagtaataa aaaaaatgaa aaaactaaac
    19921 agaaatttag atgtagttaa aatttctggg aatagaaatt tagtctattt tttctttgga
    19981 gctgaattac aatctattga tggtattgtg atttttaaag atttaaaaca tgttaaacca
    20041 aagttagatt ttataaatag aagtattcaa gctcctagat tggagtatat tacaaataat
    20101 gtatattatt ttaaaggtga actataaact tatgtagagg agatggtata aagtatgaaa
    20161 agaaaaaata attttatttg gatagttatt cttctagttg ttgtagctat gggagtatat
    20221 tatgtaggaa gaaagcataa caacacaaaa caaaaacatg ataagaatca tataaactct
    20281 gaattaaata aatccaaagt tgaaaacaat gataaaaaca aaaaagaaaa aattaatatg
    20341 gttgactata gtgattgttt tgaaggtatt agtggaggag ctatttttta taatactaaa
    20401 aataaagaat ataatatata taacaaagaa ttaattgaaa caagaaggtc accatgttct
    20461 acttttaaaa tagtttcaac tttaattggt ttagaaaaag gggtaataaa ctcaaaagaa
    20521 tcagttatgg gatatgatgg tacagagtat ccaaataaaa attggaataa aaatcttagt
    20581 ttagaagagg catttaagga gtcttgtgtt tggtactaca aaaaattgat agataaagtt
    20641 gatgctaaat ctgtccaaaa cattttagat gatttaaagt atgggaattg cgatattagc
    20701 gaatgggaag gagatttaaa aaatggaaag ggacatttaa atggattttg gttagaatct
    20761 tcattacaaa tatctccaaa agaacaagtg caaacaatgg caaaaatatt tgagggagat
    20821 acaaacttta aaaaagagca tattaatatt ttaagagata ttatgaaaat agatgtgaat
    20881 gataaaaaca taaatgtata tggaaaaact ggaacaggat ttgatgaaaa aaataaacgt
    20941 gtggatgcat ggtttgttgg tatgctagag cgtgaaggtg acacctatta ttttgctatt
    21001 aaatcagatg attccaataa agaaattaca gggccaaagg taaaggaaat tgcaattaat
    21061 ataattaaga aatattatag tgtaagggaa taaacttaat tttatttgta aatattattt
    21121 acctatagtc tgtaatattt attaaataat tttactaaat tgagtctata tagagcaaaa
    21181 ctcctttagt acataaaata cttgctattg attattaaat tgaataccta tagatttaaa
    21241 gttaatacct tttaaagact atgtaatata ttaaaagtat aaataaaata tattgcatag
    21301 tttttgtttt atattataat tttaaataat gtgcaaaaac taaacaatat ttttaatagt
    21361 aatttatatt tgtattcatg tcactataat gtcattttag gttgctaaaa tttaaccata
    21421 aaggagatga ttgtatatgg aaatattaaa atgtgaaaat ctcacaaaaa tatatggttc
    21481 aaatcaaacc agagtgacag cccttaataa tgtaaattta tcagttcaaa aaggtgattt
    21541 tgtatccatt gtaggagcat ctggttctgg caaatctaca ttgttacatc tgcttggggg
    21601 agtagataga cctacatctg gaaagattta tgttgaagat acagaaatat caagtttaaa
    21661 ggaagaagct cttgcagttt ttagacgtag aaaagtaggt cttatttatc aattttataa
    21721 tcttatacct acccttgatg ttagaaaaaa tatattatta cccatgttac ttgataaaag
    21781 aaaggtagat gaggatagat tctctgagat tgtatctata ttgggattat ctgatagatt
    21841 aaaccatctt ccaagtcaac tttcaggtgg acaacaacaa agggtatcta tagctagaag
    21901 tttaatctat agaccagcta ttttattagc agatgagcca actggtaatc ttgatagaaa
    21961 aaattcagaa gaaattgtag acttgttaaa cttatcaaat aaacgattta atcagacaat
    22021 acttcttatt actcatgatg agaaaatagc actagaggca aatcgtattg taactatgga
    22081 agatggagtg attgtctctg aaaaggtggt gaagaaatga atattcttca agaatacacc
    22141 ttagactttg tacgacgcaa taaacgtagt agtatagcta taatgttagc tatattactt
    22201 actacaacca tgatgtcttc tttgtgtgga ctgttgtata ccatgtggac agattttata
    22261 agactttcaa ttgagaaaga aggtaactgg catggtgaat tgtttgacta tacttatgga
    22321 agtgacttac cattaattga aaatttttct tcagttgatg atgtaatggt aaaaggacaa
    22381 tggtatgtag gcaaaattaa tgatgagaaa agagattata taatttatag aaatgctaca
    22441 tcagagtatt ggaattctat gccagaaaag gatactataa tagagggtcg tcgaccaaat
    22501 aatgctaatg aaattgcatt atcaaaacaa tattttgaga ataatccaag tgtaaaaatt
    22561 ggggataaaa ttactcttcc aataggagat agaatcctaa atggaaagcc tcttgaaccc
    22621 atagctcaaa aatcgaaagg ggaaagtttt aaaaaaattt cagagactac attgacaata
    22681 gtaggaaagg tagatgtttc cacttcatca gtaatacctg catatacagc tcttggatat
    22741 cttgatagaa caagtataaa acctaatgat agtataactg tgtacttgcg atttaaaaat
    22801 ataagagaca catacaagga acttccaaaa cttgctaaat cattggggtg gaagactaat
    22861 gaatatggaa aatacaatct taaatataat agtaattatc ttttaaaaat gttagtcttt
    22921 tccccagaac agaaagcatc tatgagcagt atatcaaaat tttcaactcc tattatgtat
    22981 cttacaatag caatttttac agtagctgtg tttgtaatgg tgatttacaa cgcgttttca
    23041 ctatctgcaa atgctagact tactcaatta gggatattat ctagtgttgg tgcatcacca
    23101 aaacaaatta aaatgtctgt agtgtttgaa ggttttttgc ttacaattat accattgcca
    23161 ataggtttat ttttaggatg gttattgtgt aataggctta tagtttatat taattcagtt
    23221 aattatcata ctgatgttcc agaagtggta tttacttatg gtattcctgc ttttctgcca
    23281 gcagttttac ttacaatagt aacagtctgg atttctgcac ttataccagc acgaaaagta
    23341 tcaaagatat ctcctataga agcaatacga caaggagata gtgttaaaat caaaaagtcg
    23401 cataaatatt cattaggaaa gatatttgga atagaaggag aacttgcatc aaacgcacta
    23461 cgtgctcgta aaaaatctta tcgtactgca acaatatctt taacattatc ttttttatta
    23521 cttacatgtt ttttgcatat aattgcaaat caagaaggag caaaagctgt ttatggaagt
    23581 gataattata aggaccaaag agatatagca gtttatttgg aaaatagtga acctgtagag
    23641 tctgctttca ttgaaaaatt agataataca gaaggtgtaa aaagttcact atattatcaa
    23701 aaaatgtctg cttccacttg gctgactgaa aaagatgcat caaaagaact tgcgaaaaat
    23761 ggaggattta aaagtatagt ttcatctaaa aaatactctc ctatagaacg tgatggcaag
    23821 tttcgtataa tttcaaatat aattgggctt gatgataaga gttttacaga atattgtagg
    23881 caaatttctg tagacccaaa gttattttat gatacaaaaa atccaacctc aattgtatat
    23941 aataaggagg aagatattaa tcgtagtaca cgtagaaata aagtatatat agattattta
    24001 aatctttcaa taggagataa cattaaatta aatgaaaaag tatatgacga agataaaggg
    24061 gattatactt acaacatgaa agtgggagct attacaagca cacttcctaa aatagtagat
    24121 actagttcaa aatatacatt aatgcaaata gtgccaatgt ctatggtgca ggaaatatct
    24181 aaaaattatg atgaagtaag taggttacgt tcaaataggc tgataggagt atttaaagta
    24241 aataatcgtg aggacattcc tagagtaaga gaaaaattag agtccattta taataaagac
    24301 tatggttcag gagattatag tattgaggat gttttagaaa gtgaaaaaca aaaggctagt
    24361 ggaataaaga ccatgaattt aatagtaggc tttattacag gtttattggc tatgattgga
    24421 ttatcaaatg tacttgctac agtgtcagga aatattagaa gtagacgaca agagtttgct
    24481 atgttgcgtt ctgttggatt atctccagaa ggcataaaaa agatgcttgt tttggaaggt
    24541 ttgttcttag gaattacacc attactactt agtattcctg tgcaaatagg aatagtgtat
    24601 gcttttctac gtataaatga aatatatttt atagagtatt taccatttgc acctatatct
    24661 acaataatag gttttactat attgatactt tttattgtaa tagcatcata tatgacagga
    24721 tacaagcagt tgaagaatga aaatatagta gaatctataa aaaatgaaac aatataaaca
    24781 aaagctattt gaacttattt aaaggtttcg atttaagact acttacaagt atagggatag
    24841 ttaatttgtt tgtttaataa aaccttaaat gtaaatagaa gtatattact aaaacaatag
    24901 ataacataga atatagatat agctggatta taggtatttt acctataatc cagcatttta
    24961 tgtgtaaaat ttaattatga atcttgcacc accattatgg caattttctg catgtagagt
    25021 accattttga cgttctataa tagactttga tagagcaagc cctataccaa tactgtcctt
    25081 actagcattt ttaccacgat aaaatctatt aaaaatatat ggaagttctt cctgagcaaa
    25141 ccccttacca ttatcttcta tgataatctc aacatataga ggattttgac tataataagc
    25201 aactatatat ccaccatctt ctatatgctc actacaattt ttaagaatat ttaaaagagc
    25261 ttctaaagtc caattaatat cgatttcaaa ttctaccgaa ggagaagact cgatagtaaa
    25321 tgtctgatgt ttttctctta aagaaccttc tataggctca attgcataag taagaagaga
    25381 atgtacatct ataagtttgc tttcaaatat taaagtactt gcatccaatt ttgataatgt
    25441 aagtaaagat gaaactaatc tctcaagtct tgagatttga tttgtaagtc tgttaatata
    25501 atctatttct tcatctggac aattttctga aagtaattgt gccataagtg acatagaagt
    25561 aattggagtc ttaagttgat gagcaatatc tgcaaggtta tctgaaagag tttgtctttc
    25621 ttttaaagca aattcttttg aacaacgaag ttccccaact gttttatata tctcatcttc
    25681 aaggtgagaa aattcatctt cacatcgtaa aagtacagac tcttttccta aattcacttc
    25741 ttctaagtat tgagtaagat tgtttattct actcagtttt tgcttatttg ttctatgttt
    25801 gattatatat acaactgtag ccattgttga aattatacca aacgatatca ctagaaaata
    25861 aaaaaagttt ttactccaaa atgtactttt agaatatcca tgttttgata aaatttcatt
    25921 tcctgtttta aaatccttat cactagaatt tttcagtgat tttagtatac tttctgtaga
    25981 cttaggattg tactcatatg atgcaccaag agccttagac agtacattgt attcattaaa
    26041 agaagttata gttgttagaa ttacacttaa taaaaaagtt ataattaagc agaatattat
    26101 aaaaacaact gtactgttga tatttcttgg agttttcact agctgtcctc cattctatat
    26161 cctatgcctc ttaatgtttt tatacaaggt ggatttttta atttttctct aagacgcttt
    26221 attgtaacag taagagtgtt atcatttacg aaattaccat ctacatccca gagcatttct
    26281 agtaactttg tacgagtcat agctctattt ttattttcca taagacttag aagaagttta
    26341 tattctcctg ctgtcaaaag tacttcaaca ttatctaaat atgctttgac ttcaacctta
    26401 ttcaagctta tatttccaca tgtaatagta ttgttagtat ttgaatgagt tcttctaaga
    26461 actgcattaa ttctggattg aagtactgag agcagaaatg gtttaaccac atagtcatct
    26521 gcacccatat ctaatccacg tataatgtct ttttcatcat cacggactgt caaaaatatc
    26581 actggagtat cttctatact tttaacatat tggcaaaact cgtatccaat accatcaggt
    26641 agatttaaat caagcagaat taaatcaata gttttatcaa aatttttttt agcttcagca
    26701 atcgtattat aacaacatac agtgtgattt ttcttttcaa gggaagtttt tattccaaat
    26761 gtaattgtat catcatcttc taaaagaagt attttagcca tttactttta gtcctttcag
    26821 taatttagtt atttcattaa ctaagttatt agttttatgt ttaatatttt ttatgttaga
    26881 gatagaagtt agagatagaa aaaattatca tttaagtata taaactttaa tttataaact
    26941 taggtttatg ctttaattga atctattaaa agagcaagag ttgtttcaat aaatttttcc
    27001 tcatctatat taaagttgtt caggtatgac tttcctgtta cagatagtaa attaaaaaat
    27061 cctgtaagtg taaatattga tgaatacatg agagtaggta tttcaatatc atgcctaata
    27121 cttctatcat tttttccaat ttcaaacatt ccttgtattt catcaaacat aaatttatta
    27181 aaagaaaaaa acttttcttt aaacagcata tcagtatccg atttttcaga gtttacaata
    27241 ccaatcattc ccataaggca taatagagaa ggttctacag agtaaaattt atgaaaagca
    27301 aagtatgaaa gttttatttt ttcaaaccct gttttgcctt ttgcactttc tattttaaca
    27361 ttatcccaaa gtcttttata tcctcttaag acaacagcaa agaataaatc ttctttacat
    27421 gaaaaatact tatatatggt gcgtttagta tattcaactt cctttgccaa ctcattcata
    27481 gttgtattct gaacctccca tgactaaagt cacagggttc ctgcttcata gaattttgca
    27541 tactaac
//
LOCUS       DACTZW010000055        26945 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.055, whole genome shotgun sequence.
ACCESSION   DACTZW010000055 DACTZW010000000
VERSION     DACTZW010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26945
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.055"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            19..687
                     /locus_tag="JAM15_12185"
     CDS             19..687
                     /locus_tag="JAM15_12185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799011.1"
                     /translation="MENITSYFTTILCVFICLSSVFIFTQLARVFINKKKINQKIKSR
                     NGFRYDRDFIEARREEIHIKDNNNNKNKSNNKKLKEEKVFKYDNGDLYKGEFVDGKKN
                     GFGIYIFSSKEKYEGLWKDDKMHGIGKYTYRDGSIYTGEFKYGLKNGLGKLTYPNNDI
                     YKGYFLDNKKNGKGVLYKNDGNKQAGIWEDDEQCKSLDFKDLNNNKINNVYQNRLNNN
                     KLKV"
     gene            846..1352
                     /locus_tag="JAM15_12190"
     CDS             846..1352
                     /locus_tag="JAM15_12190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HAT6799012.1"
                     /translation="MKEYVVVDLETTGLDPYKGCEIIEIGITEIKNEQIVKNYSRLIK
                     PKGIISSFITELTHISNEMVENEEPLELVLPRFRKYIGDRTIIAHNAKFDLKFLNYYL
                     RMLDLEPINNYICTVELLKKCKSYKGKNKKLETACAYYNIENINAHRADSDTLATAKL
                     FLKIKDEY"
     gene            1480..2496
                     /locus_tag="JAM15_12195"
     CDS             1480..2496
                     /locus_tag="JAM15_12195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HAT6799013.1"
                     /translation="MGYYNDNDNNKIRRKKISNNKDSNKKSKHSYTSANKKNKSPNTS
                     SSKRMSEKVDSQNLIKRDRDSFTRDNVRPLNTGYNQRERRRVEYKQREKKLKSKKRKK
                     QKRIRIVRALLSIMLVALIIFSVAGAIFTVSAIKGSPEVTKKLIRSKYISSEVVSIKQ
                     MPNDLKHAIVSIEDERFYKHKGVDVISLVRSVLNNVFTDTTQGASTIDMQVSKNLLTS
                     NDKTMKRKIRDMYNAKQMNKIMTKDEILEAYLNNMYLGKNAYGAAKGAEVYFGKKVSE
                     LNLAECAMLAGMTNNPARYIDHGEAKKRQVIVLYKMHQLGYITDKEYRIAKADDTPFK
                     SEID"
     gene            2850..3554
                     /locus_tag="JAM15_12200"
     CDS             2850..3554
                     /locus_tag="JAM15_12200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HAT6799014.1"
                     /translation="MKKFVIEDAFWNLFPSAKIGVVICNDIDNSIKDEDYKKIILKGE
                     EEALKYLEDSEFSNNQVIKVWREAFKKFKTKKGARSSIEALLKRVHNGNNIGTINPLV
                     DIYNFISLKYALPCGGEDIDKFIGDIRLTRAIGNEEFIPLGTDENSFPYEGEIIYKDD
                     SGAICRCWNWREAVRTMLTEDTNNAFLCIELVDESRFKEFENALNELAKIVQEKLGGN
                     CKISILDIDNKEVSVD"
     gene            3849..4328
                     /locus_tag="JAM15_12205"
     CDS             3849..4328
                     /locus_tag="JAM15_12205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HAT6799015.1"
                     /translation="MSNKLIKNLLSGILQILFFLLGLVIVVGGFKSFMYLCFSGEATL
                     QGTISGILMFILGVSYFIIIKSLIEVLSSSEHSLFVKDNVKRFRIIGYLLLLNSIMEF
                     ISTFGTTGKGMRFLDLGFGFYFTVPVFVYFITSLMSFVIADGFVKAIKIKEDNDLTI"
     gene            4971..5345
                     /locus_tag="JAM15_12210"
     CDS             4971..5345
                     /locus_tag="JAM15_12210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HAT6799016.1"
                     /translation="MIRKIPQAELKVMKFIWKVDVTVTSKDVIEAMEQKYGWKQTTTL
                     TLLSRLVKRGFLDAQKIDRYTHYTIRVKHKDYLSFETKDFLSNIHDDSLRSLISALHD
                     DENIGKDKLDFLESYFDNLKDE"
     gene            5338..6372
                     /locus_tag="JAM15_12215"
     CDS             5338..6372
                     /locus_tag="JAM15_12215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease"
                     /protein_id="HAT6799017.1"
                     /translation="MNNYMLYVFENLIKTTIVCSLGICLLLFLKRYLFKKFSKRFNYY
                     IWLIIVFRMLLFLFNYTIVYEVKEPKENAVGNNITQIDISTDNNLMLYVAYLWLVVTM
                     VIAVYTFIKYTRFKNLVVDVSYDIEDNDINCIYKNLLKELNIKKKIELRGSDELISPA
                     GMGLFKSYIFLPDYPYSKDELTWILKHELMHFKNKDILIKFLVLSVRIIYWFNPLVYV
                     MSNRVNLDCELCCDESVLTDCSLKNKKEYALALIKSIKLSKNYNSGILTTEFNKTSLE
                     KRLDSIVKKKGKSGILVLLILITLFSVTYFNFESISFDNSNSLRNMGILQKSGVDLKE
                     EDDISMRVIN"
     gene            6438..7025
                     /locus_tag="JAM15_12220"
     CDS             6438..7025
                     /locus_tag="JAM15_12220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding protein"
                     /protein_id="HAT6799018.1"
                     /translation="MKNLKKILIVTGCLTLISTSLVFANTTTDVDTSKDDDSIISSCT
                     ITGYEFTYENAPQSVKFDYEKKCEALNIKPSKNDIIFVNKDSIDEDEIENYVEPKAYI
                     IRYKKGYVFEVTGPKSYTLNVSDTVVGYNRVESGNPVHLVQLLCRTLDGSSIKDDGEF
                     GPATYNAVKSLQGRLGLTRDGIVGRSTWDAAGRRL"
     gene            complement(7222..8413)
                     /locus_tag="JAM15_12225"
                     /pseudo
     CDS             complement(7222..8413)
                     /locus_tag="JAM15_12225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816433.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            8928..9305
                     /locus_tag="JAM15_12230"
     CDS             8928..9305
                     /locus_tag="JAM15_12230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HAT6799019.1"
                     /translation="MMIRKIPQAELKVMKFIWKVDATVTSKDVIEVMEQKYGWKQTTT
                     LTLLSRLVKRGFLDAQKIDRYTHYTVIVKHKDYLSFETKDFLSNIHDDSLKSLISALH
                     DDENIGKDTLDFLESYFDNLKNE"
     gene            9298..10332
                     /locus_tag="JAM15_12235"
     CDS             9298..10332
                     /locus_tag="JAM15_12235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease"
                     /protein_id="HAT6799020.1"
                     /translation="MNNYMLYVFDNLIKTTIVCSFGICLLLFLKIYFFKRFSKRFNYY
                     IWLVIVFRMLLFLFNYTVMYEVKEPKENTVGNNITQIDISIDNDFMLYLVYLWLFVTI
                     AIAVYTFMEYTKFKNLVVDVSYDIEDNDVNCIYKNLLKELDIKKKIELRGSDELISPA
                     GMGLFKSYIFLPDYTYSKDELTWILKHELMHFKNKDILIKFLVLSVKIMYWFNPLVYI
                     MSNKVNLDCELCCDESVLTDCSLKDKKAYALALIKSIKLSKNYNSGILTTEFNKTNLE
                     KRLDSIIKKKGKSGILMLLILFTLFSVTYFNFESISFDNSNYLRNIGILEKTGADLKE
                     EDDISMRVVN"
     gene            10811..10984
                     /locus_tag="JAM15_12240"
     CDS             10811..10984
                     /locus_tag="JAM15_12240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding protein"
                     /protein_id="HAT6799021.1"
                     /translation="MHLVQLLCQQINGSDIDPDSKFGPATYNQVKILQGRLGVTKDGV
                     VGKATWQAVGERY"
     gene            complement(11069..12091)
                     /locus_tag="JAM15_12245"
     CDS             complement(11069..12091)
                     /locus_tag="JAM15_12245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HAT6799022.1"
                     /translation="MNYNDLLKSARENFNGTCKVCKICNGLACAGDVPGMGGKGSGSS
                     FIENRKSLEKIKINMRVIHNVSKPDTSIELFGRKMSSPIFAAPVSGTILNMGGKVSEK
                     EYIEPVVRGCSNSGIYAMVGDTNVDTFLLDNLDVLKDNRGNGIVFIKPWNNSKIIEKI
                     RLSEEAGAFAVGVDLDACGLINNQFQENPFSPKTIDEIRELVESTRLPFIIKGIMTVD
                     DALMAVESGASAIIVSNHGGRVLDYTPGTCEVLPDIAKSVKGKITILVDGGVRTGVDV
                     VKMLGLGADAVLMGRPFVTASFGGGLDGVEFFIEKVRNELCETMILTGCQNVKDIDGR
                     VIWNLL"
     gene            complement(12420..12602)
                     /locus_tag="JAM15_12250"
     CDS             complement(12420..12602)
                     /locus_tag="JAM15_12250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799023.1"
                     /translation="MYKDKSDECIHLMTAYIDSISGYYSFIDTQLEDFMMKYGENIVD
                     SNLHSIMMLLCKWGLS"
     gene            12915..13334
                     /locus_tag="JAM15_12255"
     CDS             12915..13334
                     /locus_tag="JAM15_12255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3785 domain-containing protein"
                     /protein_id="HAT6799024.1"
                     /translation="MSLYKFIYDDKEYLLKEENCSALINDEENPVQGVSISKIIDILN
                     EAEEVDFDVEYYQEACPLCLEGVKEKKKFFPFLEYHFYIFSKDGEYVISNISVDYKGL
                     SFNKLSRANKVDNSYIVSVIICENCQDYIVQIENCIV"
     gene            13465..15306
                     /locus_tag="JAM15_12260"
     CDS             13465..15306
                     /locus_tag="JAM15_12260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HAT6799025.1"
                     /translation="MEEIDDTILDSMFKLTLNERLLTNNDFIENKIDVVKNLIDCYKT
                     EQNSLMLLKSNFLLALLYGIQGFSEKMKEYILISCKYIDKCLPKDYKFLARFYSQIAI
                     LSLKNEDVNKANLYMDKFNLICDENNFLIEEIIFKSQLIYIKASKCIESSVIIKEIET
                     LYIKIKEINDFNCKKIYFFIIGKIYFLFLDDALIAKVNFLKARKYADLLKDMQVSSLC
                     NIKIGECECSFENYECSMEYFNEVISNKKYRNVNIIQKYRASNNITKILIKTRNYPVA
                     INNLAKSEVYLEKIKNHSLKEVEKFDLFISLAMYYAKSNEKSFEQSICYLDRAKNILN
                     MIKNIEEYIIYDLEIIYHQAKIYYIFGYYDNALNTNKKLLEKSKNAKNYNYVKLAYKS
                     IYLCFEKIQNYEMSMKYFKMYYELKMMYIKARNRNYIDSLNYRHEYIEKEINNMRKVK
                     LDLDKKKYVDHLTSAYNRTFLNDFLEKQEVSEYCTAFMIDVDYFKEYNDTYGHYNGDI
                     ALKNITIIIKKYLKKDMLMIRYGGEEFLILSVCKDYKKSKIFGRKLCRIVKKFLNNNL
                     TVSIGIDTCKNSSIDIKEIIENADKALYKAKESGRNRCLHYHDFKNF"
     gene            15333..17219
                     /locus_tag="JAM15_12265"
     CDS             15333..17219
                     /locus_tag="JAM15_12265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HAT6799026.1"
                     /translation="MKRSLIEDLKRNINKIEYDMLTKFYLNLTDLNYILDYHKDLLNT
                     KLEDNSRVYTLYLISLINYIKKDREASYNYLIESLKYIKKLSLKDDSDIISKIYIYLT
                     LSAISIRKYDKVNNFYFSAKKIIRQNHLNELLVLLNMSLCVEISALYQTKTDVIALVE
                     EVSFFKTLKNKALVSRANYIFGRVYLYLFNNFIKSMEYLIECLKLAQENNLYSIEAFC
                     KCIISLCYLESGNNVEAIKYINNVLDVAHSNNSISVTERVSIKIDLIWAYLKEDMNKE
                     AEVILLKTIKLMKVVEGVYKDYLYSFIFLYSAEIELKKDNCSFEKVNTYLILSKNIYK
                     SFGDVFIYNSKLDYIYKLYGDLYIKFGNIDEGISCYIKGLNLVKKSSLNLRKISIFYG
                     LIANGYELKKDFKLAIEYYKSMDWYSDRWEKNNSYKTSQAIHKQYELRQKQESLRLLV
                     DDNKKLENDILKDGLTKLYNRRYLEQQLDLFNGTRDKNMVAILVDIDCFKSYNDNYGH
                     LAGDKVIVKVTDIIRSVFIDITEHIIRYGGEEILILVDSIESIGAEEIDNIELYIKRV
                     FKLLEFEGIEHIYSKIKNYITISAGVSIKRCRSRKDVEILIEDADKNLYKSKKAGRNQ
                     YIII"
     gene            17236..19227
                     /locus_tag="JAM15_12270"
     CDS             17236..19227
                     /locus_tag="JAM15_12270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAT6799027.1"
                     /translation="MRKKIGIIASDIELKERIEELYREDVENGTIIIDILNLDLMENQ
                     GRILVEKGAQAIIGRGGGYSLVIDTVNVPVIPMNMKSTDLLRAIEIAKKYSKKVVLIL
                     GDNEVSFDYVGWRNVISTEITEEWFESKYEIRSKVVKYIDQKDEVVIVGGGLACSFAR
                     QYGIDSVFATASDESIREAVEYCKKLLDTLGEEKFNNEVLRNILDGIKDGVIAIDSNG
                     SIILYNESAKNMLKVERKCALNKYILDVFPKMEWMLDCLHEKEDVEDRKIRNINNLIV
                     NTRTTLIKVDNSTYGVLGIIQDITKLQNLERKIRFDLNQKGLYARYTFDDFLFKDKLT
                     KEFIEEAKKIGKSDYTTLLYGESGSGKEIIAHSIHNISKRKDRPFVAINCATIAENLL
                     ESELFGYEEGAFTGARKGGKRGLFELAHGGTLFLDEINSLSFNIQTKLLRVIEERQIM
                     RIGSDYIIPLDIRIIAATNESLTEKIVMGTFRADLFYRLSSLEINIPPLRNRREDIIP
                     LFNNFVNEVLKDDGLNGINSIDENFVLTKDEMDKLYNYSWPGNVRELKTIAQKYVVTG
                     KIKLRQDRDFKTKKLLPNSEVDKFNSETTASVEVQDESINISKINDGKISIDIKEVNK
                     YVEEKIISMLFAQGLSKNEVAQVLGISRTSLWKKYNKNI"
     gene            19489..20748
                     /locus_tag="JAM15_12275"
     CDS             19489..20748
                     /locus_tag="JAM15_12275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HAT6799028.1"
                     /translation="MSQSMVGKHAMWPKENDVIFSISGRAQAAEKAFGMDNVINATIG
                     ALMDDSGKLITMKTVYEEYKALDNCEIGAYAALEGQPDYLEAVKKVFFRDYLPEGHIR
                     VLASPGGSGAIKLAVWNYTNEGDEVLTSDWFWSPYVSIAEEANRKVVNYQLFDENRRF
                     NFESFKEKFVNIAEKQGRVFTIINTPAHNPTGYSVADDEWDKILDLSKEVAKDKDKKI
                     IFFVDSAYIDFAGDDDVCRKFFKKFSDLPENVLILVGFSMSKGFTAYGMRMGAIICIS
                     SSEDVAEEFHYSCVHSCRANWSNCNRSAMAVLSNIVNDPKKFKEYEDEKEIYKNMLTR
                     RADVFVKEAERVGLEILPYIAGFFVSIPCDNPKEVCEELTKHNLFAVPLKMGLRFAVC
                     AVSEDKCKKAPSIIKEALESLEVKINN"
     gene            20809..22596
                     /gene="iorA"
                     /locus_tag="JAM15_12280"
     CDS             20809..22596
                     /gene="iorA"
                     /locus_tag="JAM15_12280"
                     /EC_number="1.2.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate ferredoxin oxidoreductase subunit
                     alpha"
                     /protein_id="HAT6799029.1"
                     /translation="MKQLMTGNEAIARGAYEAGVKYASAYPGTPSTEILENIATYKDA
                     IVAEWAPNEKVALEAAIGGSIAGARTMASMKHVGLNVAADPIFTYAYTGVNGGMVLIT
                     ADEPGMHSSQNEQDNRMYAKFAKIPLFEPSTSQEAKDMIKEAFEVSEKYDTPVLYRVT
                     TRLCHSKGLVECYDREEVEIKEYVKNAKKMVTVPANAQIRRGVVEERMEILKKFSNET
                     DLNYYEINDTKIGVIASGMCCNFAKEVFGKNASYMKLGFTNPLPYEKIKEFAEKVDKI
                     YVIEENDPFIEEQIKAYGIDCIGKDVIPPYGEMTPDVLRKAIFGKTNDTIEYKSELVT
                     PRPPSFCAGCPHRGFFYELGKRKNLIVGGDIGCYTLGFAPPYNGIDYVVCMGSAFGTA
                     HGAQKVLNMKDDNEKRLVGVLGDSTFFHTGINGLLDVVYNRGNSISVILDNRITGMTG
                     HQENPGSGYTLQGAKTKEVDIEGLVKACGIEHVRVINPNNLKEVNEALDWALAIEDEP
                     SVIITRWPCVLKKFSKEDIEEFNNPFKTKCKVDHDKCIGCKLCLKTGCPALSFDKENK
                     LSNIDRNQCVGCGVCAQVCPKQAIVKEEK"
     gene            22598..23173
                     /locus_tag="JAM15_12285"
     CDS             22598..23173
                     /locus_tag="JAM15_12285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate oxidoreductase subunit beta"
                     /protein_id="HAT6799030.1"
                     /translation="MTKSILLVGVGGQGTILASKLLTMGLMEAGYDVKMSEIHGMSQR
                     GGSVSSQVRYGDCVHSPVIEIGGADILVSFEKMEALRWFNYLKPEGKALVNNHRIDSM
                     TVLIGGAEYQESDIDAELSRLNAKVINAADKAEELGNSKIMNVILLGCLVKSMQLESI
                     DWEKIISENVKPKFVELNIKAFHEGMEMVSK"
     gene            23226..24296
                     /gene="buk"
                     /locus_tag="JAM15_12290"
     CDS             23226..24296
                     /gene="buk"
                     /locus_tag="JAM15_12290"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HAT6799031.1"
                     /translation="MTYRILAINPGSTSTKIAVYDGEEQILVKTIDHPAEEIAKYNTI
                     QDQFEMRKEAVLNILKENSIDLKSLSAIVGRGGVLPPVKSGAYLVNEEMIDVLRHRPV
                     LEHASNLGAVVAHAISEPLGINSYIYDSVAVDELIDVARISGLCGMDRSSAGHALNTR
                     AMALKYAKDKGKDYKSLNLIVAHIGGGVSIYLHEKGRMVDMLSDDEGPFSPERSGRVP
                     ATKLVAACYSGQYSEREMTKKIRGKGGIVSYLNTVDAREVEKMIAEGNEEAKIIYEAM
                     AYQLAKGIGELATVVDGKVDAIIITGGIAYSEMFTSMVKKKVEFIAPVEIMAGENELE
                     SLAFGILRVLNGEEEARIYSEN"
     gene            24514..25215
                     /locus_tag="JAM15_12295"
     CDS             24514..25215
                     /locus_tag="JAM15_12295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799032.1"
                     /translation="MGKISLKSMIRLFSGFFIFAISSVLMINAHVGLMPWDVLHQGLS
                     IKLGITIGQASIMVGVVIVILDAVFGENIGWGTLLNMTFIGIFIDLVIFSGVIPHASN
                     TYIGVFMVVIGIILAAIASFLYLGVCLGSGPRDGLMIALQKKTNKSVRLVRTILEILA
                     LVVGWLLGGSVGIGTLVSALGLGYVLQIVFRIFKFDTKLLKHRFIIDDIREWKEKKSN
                     EHKCKSSIVIKNEQN"
     gene            25275..25781
                     /locus_tag="JAM15_12300"
     CDS             25275..25781
                     /locus_tag="JAM15_12300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HAT6799033.1"
                     /translation="MELWDLYNADGIKTGNVIKRGNSIEEGYYHLAVEVWILNSNSQI
                     LIQKRSKSKKTLPNMWGMTTGCIVSGEDSLEGAIREAKEEIGIDITKDEMKVFRSMIH
                     EDTLWDVYLVKKEYDISKAILQEEEVSDIKWVSTDEIRQLLKEGLFFEYPEIYELLYE
                     IDNNKLNI"
     gene            25956..>26945
                     /locus_tag="JAM15_12305"
     CDS             25956..>26945
                     /locus_tag="JAM15_12305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAT6799034.1"
                     /translation="MEDNKGLARDSSKYKIVSISVVVIILITFWYMLNMVLLTFIMTF
                     IFYNLLVATRKRIKKFSSLNIPDSLIIIVLYALFAILLVLISYAVVPIIIVQLTELSR
                     VFSDFDVNQFAQSLGPKLYPIVSKLDFNKYISQAGLLIASTATKVGSFGVNILLAFLL
                     SLLLLLEKNEIKNFGDKLSDSKISFIYNSLVFFGKSFVKNFGEVMKVQVMIAFINSVV
                     SMIFLGFMGFPQIWALGFMIFVLGLIPVAGVIVSLIPLTVIAFNTGGITKVFGVLLMI
                     CIVHAVETYILNPKLMSNRTKLPVCFVFIILLVGEHYLGVWGLLIGVPIFMFLM"
BASE COUNT        10692 a         2639 c         4501 g         9113 t
ORIGIN      
        1 tttaaagggt gattttttat ggaaaatata actagttact ttacaacaat actatgtgta
       61 tttatatgct tatcatctgt atttatattt actcaactag ctagagtatt tattaataag
      121 aagaagatta atcaaaaaat taaatcaaga aacggattta ggtatgatag agattttatt
      181 gaagccagaa gagaagaaat acatataaag gataacaata ataataaaaa taagagtaac
      241 aataagaaat taaaggaaga aaaagtattt aaatacgata atggtgattt atataaaggt
      301 gagtttgttg atggaaagaa aaatggattt ggaatatata ttttttcaag taaggaaaag
      361 tatgaaggat tatggaaaga tgacaagatg catggaatag gaaaatatac ttatagagat
      421 ggttcaatat atacaggtga atttaaatac ggattaaaaa atggtttggg aaaattaaca
      481 tatcccaata atgacattta taagggatat tttttagata ataagaaaaa tggtaagggt
      541 gtattatata aaaatgatgg aaataaacaa gcaggaatat gggaagatga tgaacaatgt
      601 aaaagtttag attttaaaga tttaaataat aataaaataa ataatgttta tcaaaataga
      661 ttaaataaca ataaattaaa agtttaatta ttctaataaa aaaatcttta tttatgatgg
      721 aatataggat atatctatgt tgtaatttgt aaaatcttcc tatatcatat aaaattaagt
      781 attgattagt ctattacata aatatagaat ataaatatat ccatttaata ataaggagaa
      841 gagatatgaa agagtatgta gttgtggatt tagaaactac aggattagat ccatataaag
      901 gttgtgaaat aatagaaata ggaataacag aaataaaaaa tgaacaaatt gtaaaaaact
      961 attcaaggtt gataaaacct aaggggataa tttcttcatt tataacagaa ttgacacata
     1021 taagtaatga aatggtagaa aatgaagaac cactagaatt agttttacct agatttagaa
     1081 aatacatagg tgatagaact ataattgcac acaatgcgaa atttgattta aaatttttaa
     1141 attactatct tagaatgtta gatttagaac caataaacaa ttatatatgt acagtagagt
     1201 tattaaaaaa atgtaaaagt tataaaggaa aaaacaagaa acttgaaaca gcttgtgctt
     1261 attacaacat agagaatata aatgctcata gagctgacag tgatacatta gcaactgcaa
     1321 aactattttt gaaaataaaa gatgaatatt aattataaat atagagaaaa ttagtgaaaa
     1381 tatcctttat aaaattgacc cttaagctta caattttgtt ctttgattta ttttgtagaa
     1441 caatgtataa tgtaccttat atgaagaagg gagactaaaa tgggttatta caatgataat
     1501 gataataata aaataagacg taaaaaaatt agtaacaaca aagatagtaa taaaaaatct
     1561 aaacattctt atacttcggc aaataaaaaa aataaaagtc ctaatacaag ttccagtaaa
     1621 agaatgagtg aaaaagtaga ttcacagaat cttataaaaa gagatagaga tagttttaca
     1681 agagataatg taagaccttt aaatacaggt tacaatcaaa gagaaagaag aagagtcgag
     1741 tataaacaaa gagagaaaaa attaaaaagt aaaaaaagaa aaaaacaaaa aaggattaga
     1801 atagttaggg cattattatc tattatgtta gttgcactaa ttatattttc agtggcaggt
     1861 gcaatattta cagtttcagc tataaaaggg tcaccagaag ttactaaaaa gttaattagg
     1921 tctaaatata taagtagtga ggttgtaagt ataaaacaaa tgccaaatga tttaaaacat
     1981 gcaatagttt ccatagaaga tgagagattt tataagcata aaggagtaga tgttatttct
     2041 ctagttaggt cagtattaaa caatgtgttt acagatacaa cacaaggtgc aagtactata
     2101 gatatgcaag tttcaaaaaa cttgcttact agtaatgata aaactatgaa gcggaaaata
     2161 agggatatgt ataatgctaa gcagatgaat aagattatga ctaaggatga aattcttgag
     2221 gcatatttaa ataatatgta tctaggtaaa aatgcatatg gagctgcaaa gggagctgaa
     2281 gtctactttg gtaaaaaagt tagtgaatta aatttagctg agtgtgctat gttagctggt
     2341 atgacaaata atcctgcaag gtatattgac catggagagg ctaagaagag acaagtgatt
     2401 gtactgtata agatgcatca gcttggttat ataactgata aggagtatag aatagcaaag
     2461 gctgatgaca ctccatttaa atcagaaatt gattaaaatt gtaagaatat agtattttca
     2521 atagtttaaa caaacaaaaa tgtaataaaa aaggtgattt gccacccatt tgccaccata
     2581 attataatct aatggcaaat tgttttaatg tacaaactag ataatagaat attgttttaa
     2641 atgctatatt atgctaaaat ttaattgtat tttgtaaatt aaaaaactta taatttagtt
     2701 ttctagggtt ccgcatttta taatggtcag gtccaagaga aaacgcgcaa ttgttgtgta
     2761 cacggaagga taaaagcctg ggagatattt aataatattt ctataggctt ttttattttt
     2821 acatatttta aatttgagga ggttttctaa tgaaaaaatt tgttattgag gatgcatttt
     2881 ggaatctatt tcctagtgca aaaattggag ttgttatttg taatgatata gataactcta
     2941 taaaagatga agactataag aaaataattt tgaagggaga agaagaagca ttaaaatact
     3001 tggaggactc agaatttagc aacaaccaag tgattaaagt atggagagag gcatttaaaa
     3061 aatttaaaac gaaaaaagga gcaaggtctt ctattgaagc attattaaaa agagttcata
     3121 atggaaataa tataggaact attaaccctt tagtggatat ctacaatttt atctcattaa
     3181 aatatgcatt accttgtgga ggggaggata tagataaatt tataggagat attaggctaa
     3241 ctagagcaat tggtaatgag gagtttatcc cactagggac agatgaaaat tcatttccat
     3301 atgaaggaga aataatttat aaagatgata gtggagcaat ttgtagatgt tggaattggc
     3361 gtgaagcagt gagaacaatg cttactgaag atactaacaa tgccttttta tgcattgaat
     3421 tagtagatga aagtagattt aaagaatttg aaaatgcttt aaatgaatta gctaaaatag
     3481 ttcaagaaaa attgggtggg aattgtaaaa tttcaatttt agatattgat aataaagagg
     3541 tatcagtgga ttaatctgga gatgctgttg taatggacta ttctagttat aaagatactt
     3601 atatttaggg taagaaggtc tattttagat ataacgatta tcaaaggata taatatagaa
     3661 aataaaaatg tagaatataa aaagccttta aaataagaaa aaaatgtatt ttaaaggctt
     3721 ttattatact cttttttatt tgtattatta acaataaaaa tatattgtta attataatgt
     3781 ttttattgaa aaacgatata atataatgta ttatactata tataaaatat tttaaatgag
     3841 ttggtatgat gtctaataaa cttataaaaa atttactaag tggtatatta caaattttat
     3901 tttttctttt agggttagta attgttgtgg gaggatttaa aagttttatg tacctctgtt
     3961 ttagtggaga agcaactcta caaggcacta tttctggaat attaatgttt attttaggtg
     4021 tatcatattt tatcattata aaatcattga tagaagtatt aagtagttct gaacatagct
     4081 tatttgtaaa agataatgta aaaagattta ggattattgg atatcttttg cttttaaact
     4141 ctataatgga gtttatttca acttttggta ctactggaaa aggaatgaga ttcctagatt
     4201 taggatttgg attttatttt actgttccag tatttgtata ttttataact tctcttatga
     4261 gttttgtaat tgcagatgga tttgtaaagg caataaagat aaaagaggat aatgatttaa
     4321 ctatttaggt gtgacacttt aatatatagg agataaataa ccagaaaaga gtgattaact
     4381 agtaatttaa aataaaatat attagggtat aatacataaa ctataatgct aaaattaaaa
     4441 gattataata ctaaaatata attatgtttt aattaaaata aagaacttta ttagtagata
     4501 ttaaaagcac atttttttat aaaagtgctt ttttataatt tattaaaggt ataattataa
     4561 aagtcttatt caataaaatt tataattaat ttagatatat ttgtaaataa tcagtataaa
     4621 atagatgttt taatagcata aaggcataat ttagaaggtt attaaaattt attagatatt
     4681 actctagttt atttttaaaa aaagtattat aatattcctt gtgtgaaaat ataggaattt
     4741 ttattaaata gttttaatgt gtaaataaca ttctacacta ttgtaattaa atatataaaa
     4801 agtaaaatat ttaaatagat atattttaaa atctaacttt caatattgta aaaaaattag
     4861 aaatttaaca aaaagtacaa aaattcacat tttttttcat aaagtgtttg actaaaaaat
     4921 tcacatgttg tagaattaag gtagcaggag ttttgaggga ggtgtaaata atgataagaa
     4981 aaataccaca agcagaacta aaagtaatga aattcatttg gaaagtagat gttacagtga
     5041 catcaaaaga tgttattgaa gctatggaac aaaaatatgg ctggaaacaa actacaacac
     5101 tgacactttt atctaggctg gtaaaaagag gattcttaga tgctcaaaaa atagacagat
     5161 atacacatta cacaataaga gtaaaacaca aagattattt aagttttgag acaaaggatt
     5221 tcctaagtaa tatacatgat gactctttga gaagcttaat ttcagcatta catgatgatg
     5281 aaaatatagg taaagataag ctagattttc tagaaagtta ttttgataac ttaaaggatg
     5341 aataattata tgctatatgt ttttgaaaat cttataaaga caactattgt atgtagtctt
     5401 ggtatttgtc tattattatt tttgaaaaga tatttattta agaagtttag taagagattc
     5461 aattattata tttggttgat aatagtcttt agaatgttac tttttctatt taattataca
     5521 atagtgtatg aagtaaaaga acccaaagaa aatgcagtag gaaataatat tacacaaatt
     5581 gatatttcta cagataataa tcttatgttg tatgtagctt atttatggtt agttgtaact
     5641 atggtcattg cagtttatac atttataaag tatacaagat ttaaaaatct agttgttgat
     5701 gtatcttatg atattgaaga taatgatata aactgtatct acaaaaactt gttaaaagaa
     5761 ttaaatataa aaaagaaaat tgaattaaga ggttctgatg aattgataag tccagcaggc
     5821 atgggattat ttaaatctta catattctta ccagactacc cttatagtaa agatgaacta
     5881 acttggattt tgaaacatga attaatgcat tttaaaaata aagatatttt aataaagttt
     5941 ttagttttgt ctgttagaat aatatattgg tttaatccac ttgtatatgt aatgagcaat
     6001 agagtaaatc tagattgtga attatgttgt gatgaaagtg ttttgactga ttgttcttta
     6061 aagaataaga aggagtatgc attagcactt ataaagtcaa ttaaacttag taagaattat
     6121 aatagtggta ttttaacaac agagtttaat aagacaagtt tggaaaagag acttgacagt
     6181 attgttaaga aaaaaggtaa aagtggaata ttggtgttat tgattttgat tacattattt
     6241 tcagttacat attttaattt tgaaagtatt agttttgata attcaaattc tttaaggaat
     6301 atggggattt tacaaaaatc aggagtagat cttaaggaag aagatgatat tagcatgaga
     6361 gttataaatt aatagattaa tatatgtaat gaaaatgtat attgtcatat tattaataaa
     6421 ttaggaggaa ttatgaaatg aaaaatttaa aaaaaatttt aatagttaca ggctgtctaa
     6481 ctctaatatc tactagtttg gtatttgcaa atactactac tgatgtagat acatcaaagg
     6541 atgatgattc aataataagt tcatgtacta taactggtta tgaatttaca tatgaaaacg
     6601 caccacaatc tgtaaaattt gattatgaaa aaaaatgtga agcgctaaat ataaaaccat
     6661 ctaaaaatga tataattttt gttaacaaag attctataga tgaagatgaa atagaaaact
     6721 atgttgagcc aaaagcatat attattagat ataaaaaagg ttatgttttt gaagttactg
     6781 gacctaagag ttatacatta aatgtaagtg atactgtagt cggatataat cgtgttgaat
     6841 caggtaatcc tgtgcattta gttcaacttt tatgtagaac cttagatggt tcaagtatta
     6901 aggatgatgg tgaatttgga cctgccacat ataatgcagt taagtcactt caaggaagac
     6961 ttggattaac aagagatgga attgttggaa gaagtacttg ggatgcagct ggaagacgtc
     7021 tttaaaaaag agagctattg cacagataat tttaaattgc tgaatctgta aacatttatg
     7081 tgtattcttt aaataaaaat ttatttttta agtgataatt aaatttttac gaatagggct
     7141 atggctttaa aaatcatagc cttattttga tatatttttc atttttgcaa aaactattaa
     7201 ccctttaaga aaaattcttg tttattttga aaaatttctt tcttcaaaat aaatacttaa
     7261 atgagctaaa atttgagcac aatttctaat tttctgagtc catttttaag aaatatacat
     7321 ggttgttaag tatagtgatt tgtgcaaata attatctaaa gtaaaaatag atttcaattt
     7381 agtaactttt cttaataatc tattctaact tcccattgaa tttgtagtat atattgatgt
     7441 atttatttct tgaggatact taaaatatgt tactaattca ttccaattgt ttcaccaacc
     7501 tcttaatact attgtatatt gattgtacta ttttttctct agtgatagct cacttaatgc
     7561 tacctcttct gtaattgtag catatctttc tttaaatctt ttatagattc ttttctattt
     7621 ttatatgata cataatttaa agtattttta atttgatgca caacatatct ttgtacttaa
     7681 gtattgggaa atatcgcttt aattgcatta gaaaattcaa ctagtctatc tatagaagct
     7741 gctattaata tatctttaat tcccatgttt ctagcatcta taagcacttt tagccaatac
     7801 tttgaaattt cattttctcc aattcatatt attaaaaccc cttttatgcc ttctaagtta
     7861 atacatatag ctatatatac tgttttgttt attattccac ctcacttcta actttataat
     7921 gtatagcatc tataaataca attgaataaa ttatattaag aggtctaagt taccatttat
     7981 gagctaaagg aataacttta tcagtagttt tagttattag tgaatgagat aatatcaatt
     8041 ccataagtac ttttaagatg acttaatata ttttgagtag acatgccttt taagtatatt
     8101 ctaatcactt gattttttat tcctaatata tcattttcat agtttctaat tacctttagt
     8161 tcaaaatctt catttcgctt tcttgaaata tttaaagtta tttctccaaa atctgattta
     8221 atatttttat ttctatatcc atttctagag tttttagtat ttttgttctt attatcgttc
     8281 tatcataacc taaaagttca tcaagctccg cttctaacat ttaatggatt gtactttcaa
     8341 ataaatcttt tagtatatct tgaatatctg taattgtttt gacatcatat tcttcaataa
     8401 atttttttaa tattttagtt tttgttaaac ataaaaagtg tacatcttcc tttgtatagt
     8461 agtgatgttt taattattat aactttttag aagaatacaa actttatttt aaagacactc
     8521 aaaatggtgt ttttatacct ttatttgata tgtataattt tacttataac ataaacttat
     8581 ataaaacaga tattttaata acacaaaggt acaattagga gattgttaaa atttattaga
     8641 tattactcta gtttatttaa ataaaagtat tataatattc cttgtgtaaa aatataggta
     8701 gttttgttaa ataattttaa tgtggaaata acattctaca ctattataat taaatacgta
     8761 aaaagcaaaa tacttgaata actatatttt aaaatctaac ttttaatatt taaaaaaatt
     8821 agaaaattaa taaaaagtac aaaaattcac attttttcat aaagcgtttg actaaaaaat
     8881 ttacatattg tagacttaaa gtagcaagag ttttgaggga ggtgtaaatg atgataagaa
     8941 aaataccaca agcagaacta aaagtaatga aatttatttg gaaagtagat gctacagtga
     9001 catcaaaaga tgttattgaa gttatggaac aaaaatatgg ttggaaacaa accactacac
     9061 taacactttt atctaggtta gtaaaaagag gattcttaga tgctcaaaaa atagacagat
     9121 atacacatta cacagtaata gtaaaacaca aagattattt aagttttgag acaaaggatt
     9181 tcctaagtaa tatacatgat gattctttga aaagcttaat ttcagcattg catgatgatg
     9241 aaaatatagg taaagacacg ctagattttt tagaaagtta ttttgataat ttaaagaatg
     9301 aataattata tgctatatgt ttttgacaat cttataaaga caactattgt atgtagtttt
     9361 ggtatttgtc tattattatt tttgaaaata tattttttta agaggtttag taagagattt
     9421 aattattata tttggttggt aatagtcttt agaatgttac tttttctatt taattataca
     9481 gtaatgtatg aagtaaaaga gcccaaagaa aatacagtag gaaataatat tacacaaatt
     9541 gatatttcta tagataatga ttttatgctg tatttagttt atttatggtt atttgtaact
     9601 atagccattg cagtttatac atttatggaa tacacaaaat ttaaaaatct cgttgttgat
     9661 gtatcttatg atattgaaga taatgatgta aattgtatct ataaaaattt gttaaaagaa
     9721 ttagacataa aaaagaaaat tgagttaaga ggttctgatg aattgataag tccagcaggt
     9781 atgggattat ttaaatctta catattctta ccagactata cttatagtaa agatgagtta
     9841 acttggattt tgaaacatga attaatgcat tttaaaaaca aagatatttt aataaagttt
     9901 ttagttttgt ctgttaaaat aatgtattgg tttaatccac ttgtttatat aatgagcaat
     9961 aaagtaaatc tagattgtga attatgttgt gatgaaagtg ttttgactga ttgctcttta
    10021 aaagataaga aagcatatgc gttagcactt ataaagtcaa ttaaacttag taagaattat
    10081 aatagtggta ttttaacaac tgaatttaat aagacaaatt tggaaaagag acttgatagt
    10141 attattaaga aaaaagggaa aagtggaata ttgatgttat tgattttgtt tacattattt
    10201 tcagttacat attttaattt tgaaagtatt agttttgata attcaaatta tttaagaaat
    10261 atagggattt tagaaaaaac aggcgcagat cttaaggaag aagatgatat tagcatgaga
    10321 gttgtaaatt aatagatttt tatagtatta taatttatta acaaattagg agaagttttg
    10381 aaattaaaaa tctaaaaaaa atcttagtag tcacagggag ggtgactcta atatctatta
    10441 gtttagtatt tgcaaatact aataatgatg taaatgtatg aaaaagtaat gaagagcaaa
    10501 caacaaattc atttacaata actggttacg aatttattta tgaaaatgta ccacaaccta
    10561 taaaatctga ttatgaaaaa aatgtaaaga attaaatata aatccatcta aagatgatac
    10621 aatctttatt aatgaaaaat ttatagattc atataatatt aatatagatg attataatat
    10681 tgaaccaaaa gcatttatta ttagatataa aaaagattta aatcgttttg atgctactgg
    10741 tcctataagt tatagcgtaa atataaatac cactgtagta ggatatggac atgtagaaaa
    10801 agggaatcct gtgcatttag tacaactttt atgtcaacaa ataaatggtt ctgatattga
    10861 tccagatagt aaatttggac ctgctacata taatcaagta aaaatacttc aaggaagact
    10921 tggtgtaaca aaagatggtg ttgttggaaa agccacttgg caagctgtcg gagagcgtta
    10981 ttagaaaaga ggttgtcgca ctaagaaata gggcgacaac ttttttatat agaatatatt
    11041 aatcagtatc ttagagtcta gaaatatttt acaataaatt ccatataact ctaccatcta
    11101 tatccttaac attttgacaa ccagtcaaaa tcatagtctc acataactca ttcctaacct
    11161 tctctataaa aaactccaca ccatcaagac caccgccaaa agaagcagta acaaaaggtc
    11221 ttcccatcaa aacagcatca gcacccaatc caagcatctt aactacatca acaccagtcc
    11281 taactccacc atcaacaagt attgttatct ttccctttac agacttagct atatctggaa
    11341 gtacctcaca agtaccagga gtataatcaa gtactcttcc accatgattt gaaacaataa
    11401 tggcactagc accagactct acagccatca aagcatcatc tacagtcata attcctttta
    11461 taataaaagg taatctagtg gattcaacca attctctaat ctcatcaatt gttttaggag
    11521 aaaaaggatt ttcttgaaat tgattattaa taagtccaca agcatcaagg tctacaccaa
    11581 ctgcaaaagc acctgcttct tcagacaatc taattttttc tattatcttt gaattattcc
    11641 aaggctttat aaatacaatt ccatttcccc tattatcctt caatacatct aaattatcca
    11701 gtaaaaaagt atctacatta gtatcgccaa ccatagcata aattccagaa ttagaacaac
    11761 ctctaacaac aggctctatg tattcttttt cggaaacttt accacccata ttcaatatag
    11821 tacctgatac aggtgcagcg aatataggag aactcatttt tctaccaaat aattctatgg
    11881 atgtatctgg ctttgaaaca ttatgtatga ctctcatatt tatctttatt ttttctagac
    11941 tttttctatt ttcaatgaaa gacgaaccac ttcctttacc acccatacca ggaacatctc
    12001 cagcacaagc taatccatta caaattttac atactttaca tgttccatta aagttctctc
    12061 tagctgattt tagtaagtca ttgtaattca tacaaaatct ctccttttta taatattaaa
    12121 attgagtatt actatattga aaatatctta attgtaaata tagggatgtt attatgatga
    12181 gctaaactag ataatacata ttagatattt tttattgttg tagatagtta aattatatca
    12241 tattagatag tcaaattttg aaaaaaacta acttatttaa gtatacattt tgaaaaaatt
    12301 aaaaaagcta tatatagatt tttaaagaaa tctatatata gcttttaagt ttatgtcaat
    12361 cttttttgtt aatgaataaa taatatagaa tacaatatac aaaaaagttt cttgaaatgc
    12421 taagataatc cccatttaca aagcaacatc attatactgt gtaaatttga atcaacaatg
    12481 ttttcaccat atttcatcat aaaatcctct aattgtgtgt caataaatga ataatatcca
    12541 cttatactat cgatgtatgc agtcattaag tgtatacatt catcactttt atctttatac
    12601 atatatatat ccccctatat acaatatata aatttagata ccaaatcgta tcatattaaa
    12661 tagttaagtg tgtaacatct atgcagttat atatttatat cattatatta ataactaaag
    12721 tgagttttga caatagattt tgggaaactg gatgttcaaa gtgcaaactt ggattttaaa
    12781 atcattaatt aagatagcgc ataggaatat atgtatacat aacttaatta taaagattat
    12841 aaacaattac ttttattaac tttatttaaa tggtagaata acttggagat taataattat
    12901 aaggaggata taatatgagt ttatataagt ttatatatga tgataaggaa tatttattaa
    12961 aagaggagaa ctgtagtgct ttaataaatg atgaagaaaa tccagttcaa ggagtaagta
    13021 tttcaaaaat aattgatata cttaatgaag cagaagaagt tgattttgat gtagaatatt
    13081 atcaagaagc atgtccatta tgtttagaag gagtaaaaga aaagaaaaaa ttctttcctt
    13141 ttttagaata tcacttttat attttcagta aagatggaga atatgtaata agcaatatat
    13201 ctgttgatta taaaggacta tcttttaata aactatcaag ggcaaataaa gttgataata
    13261 gttatattgt aagtgtgata atttgcgaaa attgtcagga ttatatagtt cagatagaaa
    13321 attgtatagt ttagtgtaaa gtatgtctta atttaagaga aatttctaaa ttgagacatc
    13381 aacttttttc aaaaatagta tggaaaatta ctaaatttat gagataatgt aagtcggagg
    13441 tgagttacaa tatatagtaa atatttggaa gagatagatg atacaatttt agattcaatg
    13501 tttaaactaa ccttgaatga aagattattg actaataacg attttattga aaataaaatt
    13561 gatgtagtaa agaatttaat tgattgctat aaaactgaac aaaatagttt aatgttatta
    13621 aaatcaaatt ttttgctagc tttattatat ggtattcaag ggtttagtga aaaaatgaaa
    13681 gagtatattt tgatttcctg taaatatatt gataaatgct tacccaaaga ttataaattt
    13741 ttagcacgat tttattcaca aatagctatt ttaagtttaa aaaatgaaga tgtaaataag
    13801 gcaaatttat atatggataa atttaatctt atttgtgatg aaaataattt tctaattgaa
    13861 gaaattattt ttaaatcaca acttatttac attaaggcaa gtaagtgtat agaatcttct
    13921 gtaataatta aagagataga aacgttgtat ataaagataa aagaaattaa cgattttaat
    13981 tgtaaaaaaa tatatttttt tattattggt aaaatatatt ttttgttttt ggatgatgct
    14041 ctaattgcta aggtaaattt tttaaaagca agaaaatatg cagatttact aaaggatatg
    14101 caagtatctt cactatgtaa tataaagata ggtgagtgtg aatgttcgtt tgaaaattat
    14161 gaatgttcca tggaatattt caatgaagta ataagcaata aaaagtatag aaatgtaaat
    14221 ataattcaaa aatatagagc atcaaacaac ataactaaaa tattaataaa gactagaaat
    14281 tatcctgtcg caataaataa tttagcaaaa tctgaagtat atctagaaaa aattaaaaat
    14341 catagcttaa aagaagtaga gaagtttgat ttatttataa gtttagccat gtattatgca
    14401 aaaagtaatg aaaaatcttt tgaacaatca atatgctatt tagatagagc taaaaacata
    14461 ttaaatatga taaaaaatat agaagaatat ataatatatg atttagaaat aatttatcac
    14521 caggcaaaga tatattatat ctttggatat tatgacaatg ccttaaacac aaataaaaaa
    14581 ctccttgaaa aatctaaaaa tgctaaaaat tataattatg tgaagttagc atacaagagt
    14641 atatatttgt gttttgaaaa gattcaaaat tatgaaatga gtatgaaata ctttaaaatg
    14701 tattatgagt taaaaatgat gtatataaaa gctcgaaata gaaattatat agattcctta
    14761 aattatagac atgagtatat agaaaaagaa ataaataaca tgagaaaagt aaaacttgat
    14821 ttagataaaa aaaagtatgt tgaccatttg acaagtgcat ataatagaac ttttttgaac
    14881 gattttttag aaaaacaaga agttagtgaa tattgcacag catttatgat agatgtagat
    14941 tactttaaag aatacaatga tacttatgga cattataatg gagatattgc tcttaaaaat
    15001 ataactataa taataaaaaa atatctaaaa aaagacatgc ttatgataag gtatggtgga
    15061 gaagaatttc tgatattatc tgtatgtaaa gattataaaa aaagtaaaat atttggaaga
    15121 aaattatgta ggattgtaaa gaaattttta aacaataatt tgacagttag tattggcatt
    15181 gatacatgta aaaatagtag tatagatata aaagaaataa ttgaaaatgc tgataaagct
    15241 ttatataaag caaaggaaag tggtagaaat agatgtttgc attatcatga ttttaagaat
    15301 ttttaactgt tgaaatagga ttggtgattt acttgaaaag gagtttaata gaagatttaa
    15361 agagaaatat aaacaagata gaatacgata tgttgactaa attctatcta aatttgacag
    15421 atttaaacta catcttggat tatcacaaag accttttaaa tacaaaatta gaagataata
    15481 gtagagtcta tactttatat ttaattagtc ttataaacta tataaaaaaa gatagagaag
    15541 catcatacaa ctacttgata gagtcattaa agtatattaa aaaattgtca ttaaaagatg
    15601 attcagatat aatatctaaa atttatattt atcttacttt atcagctatt tctataagaa
    15661 aatatgataa ggtaaataat ttttatttct cagcaaaaaa aattataaga caaaatcatt
    15721 taaatgagtt gttggtattg ttaaatatga gtttatgtgt ggaaataagt gctttatatc
    15781 agaccaaaac ggatgtaata gctttagtag aagaagtgtc tttttttaaa actttaaaaa
    15841 ataaagctct tgtaagtagg gcaaattata tatttgggag agtttatcta tatttattta
    15901 ataactttat aaaaagtatg gaatacttaa ttgaatgtct aaaattggct caagaaaata
    15961 atttatactc tatagaggct ttttgtaaat gtataataag tttgtgttat ttagagagtg
    16021 gaaataatgt agaagctata aaatacataa ataatgtatt agatgttgca cacagtaata
    16081 actcaatatc agtaactgaa agagtgtcta taaaaataga ccttatatgg gcatatttaa
    16141 aagaagatat gaataaagaa gcagaagtta ttttattaaa gactataaaa ttaatgaaag
    16201 ttgttgaagg tgtatataag gattatttat attcatttat atttttatat tcagctgaaa
    16261 ttgagttaaa gaaagataat tgtagttttg aaaaggtaaa cacctattta attttatcaa
    16321 aaaatatata taaaagtttt ggcgatgttt ttatatataa ttctaaacta gattacatat
    16381 ataagttgta tggagattta tatataaaat ttggtaatat agatgaaggt ataagttgtt
    16441 atataaaagg tttaaattta gttaaaaaga gttcattgaa tcttagaaaa atatctatat
    16501 tttatgggct aatagcaaat ggatatgagc taaaaaaaga ttttaaactg gcaatagaat
    16561 attataaaag tatggattgg tattctgata ggtgggaaaa aaataattcc tataaaacat
    16621 ctcaagcaat tcacaaacaa tatgaactca gacaaaaaca agagagttta aggttactag
    16681 tggatgataa taagaaatta gaaaatgata ttttaaaaga tggacttact aaactatata
    16741 atagaagata tctggaacag cagttggatt tatttaatgg aaccagagac aaaaatatgg
    16801 tcgcaatact ggtcgatata gattgtttta aaagttataa tgataattat ggtcatctag
    16861 caggagataa agttatagtt aaggtaactg atattataag aagtgtattt atagatatta
    16921 ccgaacacat aatcagatat gggggagaag aaattttaat attagtagat tctatagaat
    16981 caatcggtgc tgaagagatt gataatatag aattatatat taaaagagtt ttcaaacttc
    17041 ttgaatttga gggtattgaa catatatatt ctaaaataaa aaactatata actataagtg
    17101 ctggagtaag tataaaaaga tgtcgtagta gaaaagatgt tgaaatatta attgaagatg
    17161 cagataagaa cctatataaa tcaaaaaaag caggtagaaa tcaatacatt ataatttaaa
    17221 attgaggtga ttttgttgcg aaaaaaaata ggaattatag cctctgatat tgaattaaaa
    17281 gaaagaatag aagaattata tagagaagat gtagaaaatg gaactataat aatcgacata
    17341 cttaacctag acttaatgga aaatcaaggt cgtatacttg ttgaaaaagg tgcccaagct
    17401 ataattggta gaggtggagg ttatagttta gtaatagata cagtaaatgt acctgttata
    17461 ccaatgaata tgaagtcaac tgacctttta agagcaatag aaatagcaaa gaaatattct
    17521 aaaaaagtag tattgattct tggagacaat gaagtttctt ttgactatgt tggctggaga
    17581 aatgtcataa gtactgaaat aactgaagaa tggtttgaat ctaagtatga gataagaagt
    17641 aaagttgtaa aatatataga ccaaaaagat gaagttgtaa tcgtaggagg aggtttggca
    17701 tgttcttttg caaggcaata tggaattgat agtgtatttg caactgctag tgatgaatct
    17761 ataagagaag ctgtagaata ttgtaaaaaa ttattagata cattaggtga agaaaagttt
    17821 aataatgaag tgttacgaaa tatacttgat ggtataaaag atggagtaat tgctatagat
    17881 agtaatggca gtataatttt gtacaatgaa agtgcaaaaa acatgcttaa agtagagaga
    17941 aaatgtgcac ttaataaata catcttagat gtatttccta aaatggagtg gatgttagat
    18001 tgtttacatg aaaaagagga cgtagaagat agaaagataa gaaatataaa taatctaatt
    18061 gttaatacta ggacaacatt gataaaagtt gataatagta cttatggagt tttaggaata
    18121 atacaagata taaccaagtt acaaaactta gaaagaaaaa taagatttga cttgaatcaa
    18181 aaaggtctct atgctagata tacttttgat gattttttat ttaaagataa attaactaaa
    18241 gaatttattg aagaagctaa aaaaattgga aaaagtgatt atacaacttt actttatgga
    18301 gaaagtgggt ctggtaaaga aattatagct catagtatac acaatataag taaaagaaaa
    18361 gataggcctt ttgttgctat aaattgtgct actatagcag aaaatttact tgaaagtgaa
    18421 ctttttggct atgaagaagg tgcatttact ggtgctagaa agggtggaaa aagaggacta
    18481 tttgaacttg ctcatggagg gactcttttt ttagatgaaa taaatagtct atcctttaat
    18541 attcagacaa aactattaag agtaatagaa gaacgtcaaa taatgagaat tggttctgat
    18601 tatataatac ctctagatat aaggattata gcagcaacga acgaatcttt aaccgaaaaa
    18661 atagttatgg gtacatttag agcagactta ttttatagat tgagtagttt agagataaat
    18721 atacctcctt taagaaacag aagagaagat ataatacctt tgtttaacaa ttttgtaaat
    18781 gaagtattaa aggatgatgg tctcaatgga ataaacagta tagatgaaaa ttttgttttg
    18841 actaaagatg aaatggataa gctatataat tatagctggc ctggaaatgt aagagagcta
    18901 aagacaatag ctcaaaaata tgttgtgaca ggtaaaatta aattgagaca agatagagat
    18961 tttaaaacta aaaaattact tcctaactct gaagtagaca aatttaattc tgaaacgaca
    19021 gcaagtgtag aagtccaaga tgaatctata aatataagta agataaatga tggtaagata
    19081 agtatagata taaaagaagt aaataagtat gttgaagaaa aaataataag tatgcttttt
    19141 gctcaaggac tttctaaaaa tgaagttgca caggttcttg gaataagcag gacatcttta
    19201 tggaagaaat acaataaaaa tatttaaata taattacata taaattattt tgaagtaatg
    19261 ttaatttttt aaaacaagtg ttaagaaaaa ttaacattac ttttttgcaa atttttattt
    19321 ttttagacag gcatatatat ttataagaaa aatagttaaa acacttaatt taataatgaa
    19381 aaaaataata attctaaaca aaatcaattt tacataaagt gggatttatt ggcatagtaa
    19441 ttgcttaata tataatgtaa gagtaaatac aattttaggg gtgatggtat gagtcaaagt
    19501 atggttggta agcatgcaat gtggccaaaa gaaaatgatg ttatatttag catatctggc
    19561 agagctcaag cagcagagaa ggcttttggt atggataatg taataaatgc aacaataggc
    19621 gctctaatgg atgattcagg aaaattaata acaatgaaaa ctgtatatga agaatataaa
    19681 gcattagata actgtgagat aggtgcatat gcagctcttg aaggtcaacc agattactta
    19741 gaagcagtta aaaaagtatt tttcagagat tacttaccag aaggacatat aagagtatta
    19801 gcttcaccag gaggaagtgg tgcaataaaa ttagctgtat ggaactatac taatgaagga
    19861 gatgaggtat taacatctga ttggttctgg agtccatatg taagtatagc tgaagaggct
    19921 aatagaaaag tagttaatta ccaacttttt gatgaaaata gaaggtttaa ttttgagtcg
    19981 tttaaagaaa aatttgtaaa tatagcagaa aaacaaggta gagtctttac aattataaac
    20041 acaccagcgc ataatccaac tggatatagt gttgcagatg atgagtggga taaaatatta
    20101 gacttatcaa aagaagtcgc aaaagataaa gacaaaaaga taatattttt cgtagattca
    20161 gcatatattg actttgcagg tgatgatgat gtatgtagaa agttttttaa gaaattttct
    20221 gatttgcctg aaaacgttct tatattggtt ggattcagta tgtcaaaagg atttacagct
    20281 tatggtatga gaatgggggc tataatttgt atatcttcaa gtgaagatgt agctgaagag
    20341 ttccattact catgtgttca ttcatgtaga gcaaattggt caaattgtaa tagaagtgcc
    20401 atggcagtat tatctaacat tgtaaatgac cctaaaaaat tcaaagaata tgaggatgaa
    20461 aaagaaatat acaaaaacat gcttactaga agagcagatg tatttgtaaa agaagctgaa
    20521 agagtaggat tagaaattct tccatatata gcaggtttct ttgtaagtat accatgtgat
    20581 aatccaaaag aagtatgtga agaattgact aaacataatt tatttgcagt tccattaaaa
    20641 atgggcttaa gatttgcagt ttgtgcagtt tctgaagata aatgtaagaa agcaccaagt
    20701 attataaaag aagcacttga aagtttagaa gtaaaaataa ataattaatt tcattgaaca
    20761 aattgggtgg actatgaatt taataattgt agatggaggg aattttatat gaaacaattg
    20821 atgacaggta atgaagcaat tgcacgtgga gcctatgagg ctggtgttaa atatgcatct
    20881 gcatatccag ggactccaag tacagaaata ttagaaaata tagcaacata taaagatgca
    20941 atagttgcag agtgggctcc aaacgaaaag gtagcacttg aggctgctat agggggttca
    21001 attgcaggag caagaacaat ggcttctatg aaacatgttg gtttgaatgt tgcagctgat
    21061 ccaatattta cttatgcata tacaggggta aatggtggta tggtacttat tacagcagat
    21121 gagccgggaa tgcattcatc tcaaaatgag caagacaata ggatgtatgc aaaatttgca
    21181 aagatacctt tatttgaacc atcaactagt caagaagcta aagatatgat aaaagaagct
    21241 tttgaagtta gtgaaaaata cgatacacca gttttatata gagttacaac aagactttgt
    21301 cattcaaaag gattagtgga gtgctatgat agagaagaag ttgaaattaa agagtatgtt
    21361 aaaaatgcta agaaaatggt aactgttcca gcaaatgctc aaataagaag gggcgttgtt
    21421 gaagaaagaa tggaaattct taaaaaattc tcaaatgaaa ctgatttaaa ctactatgaa
    21481 ataaatgata caaaaatagg tgttatagcc tctggtatgt gttgtaattt tgccaaagaa
    21541 gtttttggaa aaaatgcatc atatatgaaa ctaggattta caaatccatt accttatgaa
    21601 aaaataaaag aatttgcaga aaaagttgat aaaatatatg ttatagaaga aaatgaccca
    21661 tttatagaag aacaaataaa agcatatgga atagattgta ttggaaaaga tgtaatacca
    21721 ccatatggag aaatgacacc agatgtttta agaaaagcta tatttggaaa aacaaatgat
    21781 actatagaat acaaatctga attagtaaca ccaagaccac caagtttctg tgcaggatgt
    21841 ccacatagag gattcttcta tgaacttgga aagagaaaaa atttaatagt tggtggagat
    21901 ataggttgtt atactcttgg atttgctcct ccatataatg gaatagatta tgttgtttgt
    21961 atgggttctg cttttggaac tgcacatgga gctcaaaaag ttcttaatat gaaggatgat
    22021 aatgaaaaaa gattggtagg tgtacttgga gactcaacat tcttccatac aggaataaat
    22081 ggacttttag atgttgttta caatagaggt aactctattt cggttatatt agataataga
    22141 ataactggaa tgacaggtca ccaagaaaac ccaggttcag gatatacttt acaaggtgct
    22201 aaaactaaag aagttgatat agaaggatta gttaaagctt gtggaataga acatgtaaga
    22261 gttataaacc ctaacaattt aaaagaagta aatgaagcac tagattgggc tttagctata
    22321 gaagatgaac catcagtaat aataacaaga tggccatgtg tacttaaaaa attctctaaa
    22381 gaagatatag aagaatttaa taatccattt aagactaagt gtaaagttga ccatgataaa
    22441 tgtataggat gtaaattatg tttgaaaact ggatgtccag ctctatcatt tgataaagag
    22501 aataaattat caaatataga tagaaatcag tgtgtaggat gtggagtatg tgcacaagtt
    22561 tgtccaaaac aagcaatagt taaggaggaa aaataatatg actaagagta tacttttggt
    22621 aggtgtagga ggtcaaggaa ctatacttgc tagtaaatta ttaactatgg gattgatgga
    22681 agctggatat gatgtaaaga tgagtgaaat acatggaatg agtcaaagag gaggttcagt
    22741 ttcctcacaa gttagatatg gagattgtgt tcattctcca gttatagaaa ttggtggagc
    22801 agatatatta gtatcttttg aaaaaatgga agctttaaga tggttcaatt atttaaaacc
    22861 agaaggaaaa gctttagtaa ataatcatag gatagattct atgactgttt taatcggagg
    22921 agctgaatat caagaaagtg atatagatgc agagttaagt agattaaatg caaaagttat
    22981 aaatgcagct gataaagctg aagaactagg aaattcaaaa ataatgaatg ttattttatt
    23041 aggatgtcta gttaaatcta tgcaattaga gtctattgat tgggaaaaaa ttataagtga
    23101 aaatgttaaa ccaaaatttg ttgaattaaa cataaaagct ttccatgaag gtatggaaat
    23161 ggttagcaaa tagtttataa tagatataaa tagactatag aaattaaggt gaaaggaaga
    23221 aaattatgac ttacagaata ttagccataa atccaggttc tacttctaca aaaatagcag
    23281 tatatgatgg agaagaacaa attcttgtga agacgataga ccatccagct gaagagattg
    23341 caaaatataa tactatacaa gaccagtttg aaatgcgtaa ggaagcagtt ttgaatattc
    23401 ttaaagaaaa tagtatagac ttaaaatctc ttagtgcaat agtaggaaga ggtggagttt
    23461 taccaccagt aaaatcagga gcatatttag taaatgaaga aatgattgat gtactaagac
    23521 atagaccagt acttgaacac gcttccaatt taggtgctgt tgtggcacat gcaatatcag
    23581 aacctcttgg aatcaactca tatatttatg attctgttgc agtagatgag cttatagatg
    23641 tagcgagaat atctggactt tgtggaatgg atagatcaag tgcagggcat gcattaaata
    23701 ctagagcaat ggctttaaaa tatgctaagg ataaaggaaa agattataag agcttaaact
    23761 taatagtagc tcacattggt ggaggagtaa gtatttatct tcatgaaaaa ggaagaatgg
    23821 ttgatatgct atctgatgat gaaggaccat tttctccaga aaggtcagga agagtacctg
    23881 ctacaaaatt agtggctgcc tgttattcag gtcaatattc agaaagagaa atgactaaaa
    23941 agataagagg taaaggtggt atagtttcat acctaaatac tgtagatgct agagaagttg
    24001 aaaaaatgat agcagaagga aatgaagaag caaaaattat ttatgaagca atggcttatc
    24061 agttagcaaa aggtattgga gagttagcaa ctgtagtaga tggaaaggta gatgctataa
    24121 ttataacagg tggaattgca tattctgaaa tgtttacttc aatggttaaa aagaaagttg
    24181 agtttatagc accagtagaa attatggcag gagaaaatga gttggaatca cttgcttttg
    24241 gaattttaag agtactaaat ggagaagaag aagctagaat ttatagtgaa aattaataag
    24301 aaaaactaaa aatgtttata tactaaaaaa gtggtatatc cgttttttat acacgaaagc
    24361 ttagagtata ggtgaaaatg tataaaattt ggattgccac tttttataat taaaatttta
    24421 tcttaaccta ataaataatt ctgtaaaatt tcgtatttat atatatattt tattggtatt
    24481 tattgttatt attattatga ggagtgattt ttgatgggaa aaataagttt aaaaagtatg
    24541 ataagattat tttcaggttt ttttatattt gcaatttctt ctgtgcttat gattaatgca
    24601 catgtaggtc ttatgccttg ggatgtactt caccaaggtt tatctataaa gctaggtata
    24661 actataggtc aggcttctat aatggtagga gttgtaattg ttatattgga tgcagttttt
    24721 ggtgaaaata taggatgggg tactttactc aacatgacat ttataggaat ttttattgat
    24781 ttagtaatat tttctggagt gatacctcat gcaagcaaca cttatatagg tgtgtttatg
    24841 gttgttatag gaattatttt ggcagctata gcaagttttc tatacttagg tgtttgttta
    24901 ggaagtggac cgagagatgg gcttatgatt gctcttcaga aaaaaactaa taaatctgta
    24961 cgtcttgtta gaacaattct tgaaatacta gcattagttg ttgggtggtt attaggaggt
    25021 tctgtaggta ttggtacgct tgtaagtgct ttaggtttag gatatgtatt acaaatagtg
    25081 tttagaatat ttaaatttga cacaaaattg ctgaaacata gatttattat agatgatata
    25141 agagaatgga aggaaaagaa aagtaatgaa cataaatgta aatcaagtat tgtaataaaa
    25201 aatgagcaga attaattatg ctaaaatata tttgtagttt atctaattta tagtaaagtc
    25261 aaggagattt tgaaatggaa ttatgggatt tatataatgc tgatggaatt aaaacaggaa
    25321 atgttataaa aagaggtaat tctattgaag aaggttatta ccatttggca gttgaagtgt
    25381 ggattttaaa tagtaactct caaattttaa ttcagaaaag gtctaaaagt aaaaaaacat
    25441 tgccaaatat gtggggaatg acaactggat gtattgtttc tggggaagac agtttagaag
    25501 gagcaattcg cgaagcaaag gaagaaatag ggatagatat aactaaagat gagatgaaag
    25561 tttttagaag tatgattcat gaagatactc tttgggatgt atacttagtt aaaaaagaat
    25621 atgatatatc taaagctatt ttacaggagg aagaagtaag tgatataaag tgggtaagca
    25681 cagatgaaat aagacaatta ctaaaagagg gtttgttttt tgaatatcca gagatatacg
    25741 aattgctata tgagatagat aataataaat taaatatatg atgtagagca gatttcagta
    25801 taagtaagat tatttaaaat gtatcttctc taaattttaa tattgtttta tgaaaattaa
    25861 taagttattt ttagtatttt tctacttgtt ttttgagatt aaaataaaaa gggcagtcat
    25921 tataaagtca taaaaatttg gggaggattt aaactatgga agataacaaa ggattggcac
    25981 gtgacagttc aaaatataaa attgtttcta tatctgtcgt agtaattatt ctaattacat
    26041 tttggtatat gttaaatatg gtgcttttaa catttattat gacttttatt ttctataact
    26101 tgcttgtagc cacaagaaaa cgaattaaga agttttcttc tttaaatatt ccagattcat
    26161 tgataattat agtgttatat gcactatttg ctatattgtt agtattgatt agctatgcag
    26221 ttgtaccaat aattatagtt caacttacag agttgagtag ggtttttagt gattttgatg
    26281 taaatcaatt tgctcaatct ttaggaccaa aattgtatcc tattgtctca aagctggatt
    26341 ttaataaata tatttcacaa gcagggctac ttatagcatc aacagcaaca aaagttggaa
    26401 gttttggagt aaatatatta ttggcatttt tactgagttt actcctttta cttgaaaaaa
    26461 atgaaattaa aaattttgga gataaacttt ctgatagtaa gatttctttt atttataatt
    26521 cgcttgtatt ttttggaaag agctttgtta aaaattttgg tgaagtaatg aaagtacaag
    26581 ttatgattgc ctttataaat tctgttgttt ctatgatttt cttaggtttc atgggattcc
    26641 ctcaaatatg ggctttagga tttatgattt ttgtgttggg tcttattcca gtagcaggag
    26701 ttatagtgtc tttgattcca ttaactgtaa tagcatttaa tacaggagga ataacaaagg
    26761 tttttggagt tttacttatg atttgtatag tgcatgcagt agaaacatac atattaaacc
    26821 ctaagttgat gtcgaataga actaaacttc cagtttgttt tgtttttatt attttacttg
    26881 taggagaaca ttatttaggt gtatggggat tactaattgg agttccaata tttatgttcc
    26941 ttatg
//
LOCUS       DACTZW010000056        26763 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.056, whole genome shotgun sequence.
ACCESSION   DACTZW010000056 DACTZW010000000
VERSION     DACTZW010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26763
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.056"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(329..1930)
                     /locus_tag="JAM15_12310"
     CDS             complement(329..1930)
                     /locus_tag="JAM15_12310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HAT6799035.1"
                     /translation="MIYDLILKNGFIIDGTGNPGFYGDIAIKDNLIAKIDSKINSNTN
                     KEIDCCGKVITPGFIDPHVHEEIVAILDGKFEKFLKQGVTTTINGNCGHSITPYSSEN
                     VYEYMYKNGLLLEEEKKYLIDKNKCWNNFAEYCDLISKSGISVNMGFLLGHGTIRWSV
                     MGGSKDRPPTEKEKNEITDIINDGMKSGAFGISTGLAYIPSKYADIDELVDIARQIKE
                     HDGIYTSHIRDYIGRYNAVKEAIEVGQKSGARVQVSHLSPVEIEAFDEILKARYNGVE
                     IMVDTVPRSSGHCMKKKRVIQFIMAISSSLFELGIDGVMDALRNEEGRTLILKEAFIL
                     GDRGSIILLNTKDINMEKKSIREIATQKGIDEDKLLLDLLLDGDEELIFCLGGMYRAD
                     FPDKLHDNKIIDNPFVMVGSDCLFSVGGDMSWFELQRRGAFPIFFNMYRKSGVRLEEI
                     VRRVTSLPARQFKIKNRGIIKEGLIADIAVIDMDNYSYSRSEDIDFSKPQLLANGVEY
                     VIVNGKIALENGDITENKCGEVLKR"
     gene            complement(2041..2718)
                     /locus_tag="JAM15_12315"
     CDS             complement(2041..2718)
                     /locus_tag="JAM15_12315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799036.1"
                     /translation="MSKVKSIYNEEYLPFMIRYGRLTLSLGIIAALVPGIILSFGFGI
                     MPPISALLASTMAIVSMSAPNYIIEPVSYSPILGIPGTYMSFLSGNISNMRLPCSIAA
                     QKAAEVESGTEEGSIISTIGIAVSILVNISILTIGVILGGSVLSKIPAEVVEKLNLIL
                     PALFGSVFGQVFLQDKKLGLVAIVISVLTIILSKQGIIPQSLVVLICVFGTILIARAM
                     YKDKLSE"
     gene            complement(2731..3426)
                     /locus_tag="JAM15_12320"
     CDS             complement(2731..3426)
                     /locus_tag="JAM15_12320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HAT6799037.1"
                     /translation="MDYLKLANHPLLWIASTVAVSIVVVQSLIFAIKSCKVGKTMGIT
                     DKQIKSAVKSSAISAIGPSMTIFAGMVSLIVTMGGPIAWMRLSFIGSVIFESMSAGFG
                     TDALGITLGSPEMTKLAFTNAVWTMILGSLGWIIFTLLFGHKLDKITNVISSGKKSFI
                     PIISLGAMLGSFAYLNADRVLRFDNGTIACISGMAIMVILCMLEKKKNIKWLREWGLT
                     ISMFSGMIIASVI"
     gene            complement(3478..4677)
                     /locus_tag="JAM15_12325"
     CDS             complement(3478..4677)
                     /locus_tag="JAM15_12325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAT6799038.1"
                     /translation="MKSAYKGYEAYSYLEKGKDISSIEMCKGDKRVKEYLIELDDIQE
                     AKVKSIVDEKIFISLHEHPVLFPEHLERDIFEYNREGKQRCAYEALSRGYYDAIFDNL
                     MDGVCTITSNSGWKWDDILIDLGMRLCDLAHQDFVIKCEKVEDIYRAKSEGKVALIPT
                     LEGAAPIENELDRIDILYGFGIRLMGITYSESNALGSGLKEEKDGGLTNFGKKAVERM
                     NKIGMAIDCSHVGVQTTLDVIEYSKDPIILSHVGARSLWNTKRLTPDEVLIACAKKGG
                     VIGVEAAPHTTITEKNKEHSIESFMEHFEYIKNLVGIDHVAFGPDTVYGDHVKLHSVL
                     AAKFDIKKITGTKEHPKVEYVKGLENPTETSKNIVRYLVKHGYSDEEIEKVLGGNILR
                     VLKQVWK"
     gene            complement(4938..6983)
                     /locus_tag="JAM15_12330"
     CDS             complement(4938..6983)
                     /locus_tag="JAM15_12330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAT6799039.1"
                     /translation="MKKHNILFVSTDDKINIDISKQLENIFGEFCNIDNLVYVNRINI
                     ELSSYELVVCSDNDIKEYIHNNIDKNIPIVIVHRTINIENINQIISIENDSDVMVIDA
                     YKESADETAKIIRKLGLIHINLIPYYPGCDKSKCEIGIITGSRNSIPQNIKQIIDIGD
                     KVIDINTVIEIFTKLNISIDKLHIIKEKYNEDTVSGYRYYTTMNKTMKSFLEIIDEGI
                     ASVDKLGKFIYCNKVFSNLVGIDQNEIISNNFMDLFSDKVVKKIFFQEDEVNDEVVNL
                     NNKKLIINKVNVYENNERIKSIISIKNISAIQVLEDKIQNKLQSKGFVSKYTFESVVG
                     ESKIIKEKINIARKIATTDFSVLILGENGTGKEIFAQAIHNESLRKNKPFVAVNLSSL
                     SDTLIESELFGYDEGSFTGAIKGGKIGIFERAHTGTIFLDEIGDISLDVQQRLLRVLQ
                     EKEVMRMGGSKIIPIDVRIIAATNKDLKKKIKEGSFREDLYYRINVLHIEIPRLRERK
                     EDIPLISKYFLDEINSNKCFTEESMQALTLYEWPGNVRELKNLIYYIDTIVEEDRVDY
                     EHLPEQFRFEKNNTLVNENFDSIILDFKQSNFFEESICILTSIETWNNKNILLGRNKL
                     QEILKEKDIVLSVDQIRKRIDKLKSHGLLLSGVKKQGSFITDEGKNFISYVKIKGVI"
     gene            complement(7394..8203)
                     /locus_tag="JAM15_12335"
     CDS             complement(7394..8203)
                     /locus_tag="JAM15_12335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAT6799040.1"
                     /translation="MYYVYVNDINIAVYDLNPSAKKTVLFIHGWPLGHKIFEYQTNIL
                     PKLGYRTVSIDLRGFGKSDATSGGYTYSQLADDIYKVVHAIGLKDFTLVGFSMGGAIV
                     LRYMSLFNGYGVSKLVLAAAAAPSFVQRPPEFPYGMTREDVNKLIAQACTDRPEMVND
                     FGEKVFASNPPESFRRWFNDIGFSASGIGTIGTAVSLRDEELFNDLKCVRVPTGIFHG
                     KLDEICPYEFAVFMNEKIEDSILYTFEYSGHAIFYDELKLFNQEFLQFLEE"
     gene            complement(8287..8820)
                     /locus_tag="JAM15_12340"
     CDS             complement(8287..8820)
                     /locus_tag="JAM15_12340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterioferritin"
                     /protein_id="HAT6799041.1"
                     /translation="MSDAHYDMHKRNGYSSDEPYPEIKVLGPNKYYAELLMDDYAGVS
                     SEFTSVNQYLYHNFDLDETHRELSEMWINISITEMLHMEILAKTIRLLGGNPVYRGST
                     SSCGAYWNGGFVCYGNSICNRLKLDLHLEHVAINNYYKDISLIEDPYIKAILNRIILD
                     EKLHVSLFEKAIEKYCK"
     gene            complement(8970..10319)
                     /locus_tag="JAM15_12345"
     CDS             complement(8970..10319)
                     /locus_tag="JAM15_12345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HAT6799042.1"
                     /translation="MELKNFKDILFKKALSEGFEECEIYYYTGENLSINIYEGEVEKY
                     NLDKSFGLSFRGKVNGKIGYSYTEILDDKAVDMLIKNVKDGVNTIENEDVQFIYEGDK
                     HYNDVKTYSKELENLEADKLIDLALEMERETKAYSDKVVNLSKCTISYSVSSNGISNT
                     KGLNLSNKTNMLIGFVVPIIEDNGQKYDGIGYNIANSIEEIKPCEISKLGVDNALSKV
                     GGKSIPSGKYKTILLNEAMVSLLSTFSGIFNADSAQKGLSLLKNREGDMIASPIVTIV
                     DDPLLENGMASTPFDDEGVATFKKEVVLNGKLITLLHNLKTANKAGVKTTGNGIKSSY
                     SSPISIYPTNFYIEKGDKSLDEIIKDIDEGLMVTSFAGLHSGANSVTGDFSLAAKGFY
                     IKEGKKVFPVEQITVAGNYFDLLKDIEAIGEDLEFPMSSIGSPSVVIKELSVAGKDE"
     gene            complement(10331..11713)
                     /locus_tag="JAM15_12350"
     CDS             complement(10331..11713)
                     /locus_tag="JAM15_12350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HAT6799043.1"
                     /translation="MLSKNIASKVLEKCLITGGDFAEIFEEDTINNSISLIDNKVENA
                     IGGRNYGIGIRIFKGLKSIYAYTSDNSLNSLLDVAYKAAVALGKLEDGKSVILNDSIK
                     INNIHNIKIYPNSIGNRDKVSAMKVAYKSAKEFSNDISQVSVSYLDKDQKILIANTEG
                     IYVEDRRIRTRLGISSIASKGNENQTGFEGPGGCKGFEIFEEIDPEYYAKESARVAHT
                     MLHAKNCPAGNMMVAIDNGFGGVIFHEACGHSLEATSVAKGNSVFADKLGQQIASTKI
                     TAIDDGTIPNYWGSMNIDDEGNPTQKNILIENGILKSYMIDKLNGRRMGMNPTGSSRR
                     QNYKFAPTSRMTNTYIAAGEDRPEDIIKSIPDGLYAKKMGGGSVNPVTGEFNFAVSEG
                     YLIKNGEIQEPVRGASLIGKGSDILMNIDMVGNNVKQAQGMCGSSSGSIPTNVGQPMI
                     RVKEITVGGR"
     gene            11957..13171
                     /locus_tag="JAM15_12355"
     CDS             11957..13171
                     /locus_tag="JAM15_12355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAT6799044.1"
                     /translation="MNQEYVKGNPIFTNINKVPRQFPYLTDDIDTDVIIVGGGVTGCI
                     CAYYLAKNNIKSVILEKGRIAHGSTSVTTSLLQYELDDNLIDLTEVMTLKDALKAYNL
                     CTSALEELDTFIELYGNKCDYAKRDTLLYTANKLEVKAIKEEYNLRKENGFDVEYIDE
                     STNPFSFDLKSGLIAKNGGRELDPYKYSHHLIDVSLKNGLQVYENTEVKKVDLSNDKV
                     TAEVSYGYKVHGKKLIVATGYNTSLFTKRNFATKSNTFNIATKPLKNIASWKNNILIR
                     DNCDPYNYLRTTKDNRLIIGGEDVSFDDIENETLANEKYDILEQRLKSMFKDIKDIEV
                     EYKYCGCFASTLDNLGFIGPDNKNNNLWYCLGYGANGILFAILGGIMLSELYLGKQNK
                     NMKLFKVDRFDK"
     gene            13369..15261
                     /locus_tag="JAM15_12360"
     CDS             13369..15261
                     /locus_tag="JAM15_12360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HAT6799045.1"
                     /translation="MKEILVIAPTKGTYEKSIHIVKKNKYTNIDVVFGNLKEGIPLAE
                     KSINHGTRIIISRGGTYNMLKATYNIPIVEIKVDAYDIIKSYKEVKNSNEPFGIIGFN
                     NVIYGFDIIEEILNKKITMIEIEKEEEIYDAIEKYRKKGINTYIGDTTVAHIVKRLNC
                     KGILIESREENILRAIQQAEQILEATKDEQKRRLQIEAMTDFVHDGIITVDKNFKITL
                     FNKSAEKIFGIKKENALYHNVVDVIPNTVLPQVVETMEPQIGEIQNIGSTKIITNRVP
                     IIVDGQIQGAVSTFQDSKEISSFEHTIRRSLLSKGLSAKYTFDDIIHASEKTKDCIEL
                     AKKYACYDTPMIITGESGVGKELFCQSIHNYSKRKNAPFVAVNCAAIPPSLIESEFFG
                     YEEGSFTGARKKGKAGVFELAHEGTIFLDEISEIPLELQGRLLRVLQEKQVMRIGGDK
                     VIPIDVKIICASNKDLKNMMRNGLFRQDLYFRINILTLYLPSLKERKEDIIKLSEFFI
                     HKYSSKYNKTPLIITPNIKKALLEREYEGNIRELEGMMERAVIVESFDSILLEKVSNE
                     YTNNIVDKDNSDFKCSNLDLKTLEKKYIYKIYNENNRNTTKTCEILKITRSTLWRKLK
                     EIENDV"
     gene            15532..16506
                     /locus_tag="JAM15_12365"
     CDS             15532..16506
                     /locus_tag="JAM15_12365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HAT6799046.1"
                     /translation="MHILKSVKKIPGGLMVCPLLLGALFNTVCPQALEIGGFTTSLFK
                     TGAMSILALFCLCNGAQINIRQAGKPLTKGIVLTATKFIIGAVLGIIVSKFIGPKGII
                     GITPLAIVATMTNSNGGLFAALAGEYGDSTDVGAISILSLNDGPFFTMLAFGVTGLAN
                     VPIVALFAALIPILLGFILGNLDEDIREFLAPGTTLLIPFFAFPLGAALNFNQIITAG
                     LPGVVLGLGVTIITGMGGYFVMKLIRAEHPAVGAATGTTAGNAAGTPEALAAIDPTLA
                     TIAAVSTVQVAAAIIVTAICCPMLVSYLDKREKKKKSIFKTNKNIEVN"
     gene            16527..16802
                     /locus_tag="JAM15_12370"
     CDS             16527..16802
                     /locus_tag="JAM15_12370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HAT6799047.1"
                     /translation="MNAIIHANEKDNLVTCVRPLVKGEKVSIDGKSYIVNDNIPVFHK
                     MATEDVKKGDVVYKYGEIIGIATVDIKTGDYVHVHNIESTRGRGDKK"
     gene            16815..17978
                     /locus_tag="JAM15_12375"
     CDS             16815..17978
                     /locus_tag="JAM15_12375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015262681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HAT6799048.1"
                     /translation="MKLMGYLRENGQFGIRNHVLIIPTSVCSSETATRIASLVPGAIA
                     IPHQHGCCQIGSDIELTAKTLIGFGKNPNVAAVLVVGLGCDGIQAKELASEIATTGKK
                     VDYVVIQECGGTLKTVSKGTEIVSKMAREVSKEVRVEFGMSEITLALECGGSDPTSGI
                     ASNPSIGVASNLLVDEGGSSILSETTEVIGAEHLLATRFEDEEMKDKFLKFVSDVEKR
                     AIAMGEDLRSGQPTPGNKAGGLSTIEEKSLGCMYKAGNKPFKGALEYADIVPPDKKGL
                     YFMDTPGQDIDSITGMVAGGAQIVIFSTGRGTPTGSPISPVIKITGNSDTYNKMPDNI
                     DINAGRIITDGAKIADIGQEIFNEIIEVCNGKHTKAESLGHREFGIYRISSTF"
     gene            18315..20594
                     /locus_tag="JAM15_12380"
     CDS             18315..20594
                     /locus_tag="JAM15_12380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HAT6799049.1"
                     /translation="MNFENTKNKKIIATLLLTLLLIVSLTCVTFIMNLNKVTHNETER
                     YLVEVSQSISTTINVKCKSIFRTLYSMGDTYFEINDSEKEVNRYLSKKLKLFEFDWLG
                     IIDSNGNFVSALKDTGNVKGQDFYRKALQGKETITPVKSQSGTYGILYSVPLYNGDKI
                     VGAVAAWNTIDTMRNLLSVESFHGEGFSQIIDQDGNFIVSSANKNAPKNVVNFFDMIK
                     HQGKQVDKNKLEEMKINLKKNKTGSMYYTLNDGISKAMHYLPLQEENLYLLSVVPTKT
                     ASAQFDLLLKKAIFINILIVILFLLLIILIMFINQKNRAQLIKIAYVDSVTKGYSKAR
                     FDIEAKKIIQSSSSESYSLVSINIQKFKLINDSFGSEAGDKTLKYIHDVISNYLEPGE
                     LLCRVSNDQFNVLIKTIPQKEILKYIENITNDINSFNKNEECKYFIALSIGVYKIDDP
                     NLPLVSIQDRANVARKNNKGNIGNHPLYTCVFYSDLERLKMIKEKEMENRMEEALNNN
                     EFIVYLQPKISLKDNTIVGAEALVRWQDPNKGLIPPDEFIPFFEKNGFITKLDHYVFE
                     KVCSMIRKWIDNGETPMPVSVNFSRANLNNIDFLEKYRMLRNKYNIPAKLLEIELTET
                     LVFENLQKLINIIDQIHEEGFQCSLDDFGSGYSSLNMLKEIKVDTLKLDRAFFSSPNA
                     DNIAENHVIESIVNLAKKLNMNSISEGVETILQMDYLKKINCDMIQGYVFSKPLPQEI
                     FEKMTFGKKLEETSMDSSV"
     gene            complement(20689..22029)
                     /locus_tag="JAM15_12385"
     CDS             complement(20689..22029)
                     /locus_tag="JAM15_12385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HAT6799050.1"
                     /translation="MENQEALRHEKIWILLFRYSIPAIIAMMVTSLYNVVDRAFIGSM
                     EGIGSIAIAGLGVTMPVFTLIIAFGMLVSVGASTRLSIKLGERNREEAEKILGNALTL
                     SIIISLIITISGLVFLEDILFILGASKDSIFYAKDYMSVILIGSIFNLVAFSLNNAIR
                     AEGNPKLAARTMIVGCVLNLILDPIFIFVFNLGIKGAAIATVLCQIVVFFWVIHYFIR
                     GKSNLKLKKCNLKLNKDIVKKVFAIGMTPFAMEVAISITHMFTNNSLKVYGGDLAIGA
                     MTALTSILLMFMMPVFGLNQGMQTIISYNYGAKQYERAKKTLILSIIVSVVILSFGFL
                     VVQVFPEVFVGIFNKDSDLMDIAVRGISINLITLPIMGISIVGPVYFQCISKVKHSMF
                     LTLLRQFILFIPLIIVLPIQFNLDGVWLAQPVADFIAMIIVLLFLKREFKTSRV"
     gene            complement(22041..22823)
                     /locus_tag="JAM15_12390"
     CDS             complement(22041..22823)
                     /locus_tag="JAM15_12390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017825045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6799051.1"
                     /translation="MNCINTKNLNVSYGNTDIIKNLNLNIPKGKITTIIGANGCGKST
                     ILKTIGRIISPNSGKIYINGEDIYKKKSKEIAKDMAVLPQSPQAPSGLTVSELISYGR
                     FPHKSGFGNSSKEDREIVNWSLEVTGIAEFKDRNMEDLSGGQRQRAWIAMALAQETDI
                     LLLDEPTTYLDLAHQLEILKLLDELNKKQGRTIVMVIHELNNAARFADHMIGIKKGKI
                     VCEGDAYDVMTKDNLKELFNIDAEIATDPRTNKPICITYDMV"
     gene            complement(22838..23860)
                     /locus_tag="JAM15_12395"
     CDS             complement(22838..23860)
                     /locus_tag="JAM15_12395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HAT6799052.1"
                     /translation="MKNIIKINSKTLLVISILMVLIFITFLLSLNMGSFSIEPMDVIK
                     TFLGQGQRNHEIAIFKLRLPRIVIALLVGSALSTAGVILQGVTKNDLADSGILGINSG
                     AALFVVVYIYLMNGNVYEGMSNLTVFTMPIVALIGALFGAFLIYSLAWKGGINSSRLL
                     LIGIGVNIAFTSILTIFQLKFTTQEFNRVMAWTSGSIWGTSWKYVIAVLPFIVIFMGI
                     TIYKSKYIDVLNLGDEVSISLGVDVEKQRRRLIIYAVILSGVSTAVAGSISFLGLIAP
                     HIGRKIIGPKHKRLIPVSALIGTLLLLIADTISRNLLAPIEIPVGIVVSIIGVPYFIY
                     LMLVND"
     gene            complement(23866..24879)
                     /locus_tag="JAM15_12400"
     CDS             complement(23866..24879)
                     /locus_tag="JAM15_12400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003370238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HAT6799053.1"
                     /translation="MTKLSKKNITYLLILVSIVVLVFGIVLSITIGAKDMNLSTVIDS
                     LIKMEDGINMRIVKDVRLPRAIAAALVGGFLAVSGAIMQGITRNPIAEPSVIGITQGA
                     TFAISISLVLQKKLPQLIHGSFSVMMFAFIGASISGLFIYFISSKSRGRVNNVKLALA
                     GVALGTLLISLASAISMYFNLSQQLSFWISGGLVGVKWEGIKLLFVAGGIGFILAIIM
                     APRITILSLGEEVAIGLGQKTNFVRFICIVLVILMTGASVSVSGNIIFIGLIVPQIAK
                     GIVGSDYKYIIPSSLVLGAVLLVYTDILSRMINPPYETPVGSITALIGVPIFIYLVRK
                     GEK"
     gene            complement(25007..25945)
                     /locus_tag="JAM15_12405"
     CDS             complement(25007..25945)
                     /locus_tag="JAM15_12405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAT6799054.1"
                     /translation="MKKIKSLAIFISIITTLVLVTACSDKNTEDKDKSETRVVQSVKG
                     EVKIPSNPKKIVDISGSSEELLLAGYKPVATANVDSYETDKLPSYIREELKGVKIVGH
                     SMMDTMDMEAILEVNPDLIIMSQRQEKIYDQLKEIAPVVMMKDYANDWRSKLTDVSKL
                     FDKEEEAKSWLQKYDEKATKLGKEVIEKNGEKTYLPVLASSGQFMVFSDGGIGTLIND
                     DMKLDRPKNMPKQDGITLPMVSMEGLTDIDADHIVVIATEADKKDLENSAIWAQIRAV
                     KDGNVTILDAAPFFSQSYNPIGKELLLESVKNELTK"
     gene            26215..26679
                     /locus_tag="JAM15_12410"
     CDS             26215..26679
                     /locus_tag="JAM15_12410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016208838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799055.1"
                     /translation="MVHLVYCDNAGKKGEKVLDKILAGTKTMVIRGAAGRKIPHSRVF
                     EDELLYFMEKGTGKISAKATVKKVENYVKLTEDEISKILNENQPKLNLSEKQKVRWHK
                     KCLCLVEFENVEEITSLDFDHQGNMDDWLIVEKIEDVVVGTSIPYNYEKSKF"
BASE COUNT         9308 a         4422 c         3343 g         9690 t
ORIGIN      
        1 aactaaataa cccctttaat atttatgact gtctatttga taaatattaa aggggttatt
       61 tagttatcat tttttatttc taaaaatctt ttctcaaatg atttagttat ctatttatcc
      121 aattttttac ataatttaat gattaaaaat attaattttt tcactataaa gtataaatat
      181 tttttgtata aatattatct gattattaaa ataaatatta atactataaa taaaaacgaa
      241 gcatgatttt tatttaaata aatcccaaac ttcgtcttta cttacttaga tatttattta
      301 ctttctaaat cctattattt ttaaaacctt atctttttaa tacttcacca catttattct
      361 cagtaatatc tccattttct aacgcaattt ttccatttac aattacatat tcaacaccat
      421 tggctagtaa ttgtggcttt gaaaaatcaa tatcttctga cctagaataa ctatagttat
      481 ccatgtcaat aactgctata tcagctatca acccttcttt aataatacct ctatttttta
      541 ttttaaattg cctagctggt aatgaagtaa ctcttcttac aatctcttcc aatctaacac
      601 cagactttct gtacatattg aagaaaattg gaaaagctcc tcttctttgt agttcaaacc
      661 atgacatatc cccacccaca ctaaacaaac aatctgaacc aaccataaca aatggattat
      721 caattatttt attatcatgt agtttatctg ggaaatcagc tctatacatt cctcctaaac
      781 aaaagataag ttcttcgtct ccatctaaaa gtaaatcgag taataacttg tcctcatcta
      841 ttcctttttg tgtagctatt tcacgtattg atttcttttc catattaata tctttagtgt
      901 ttagaagtat tatactcccc ctatctccaa gtataaatgc ttcttttaat ataagtgttc
      961 ttccctcttc atttctaaga gcatccatta ccccatctat acctaattca aatagactag
     1021 atgatattgc cataataaat tgaattactc tttttttctt catacaatgc ccagaacttc
     1081 ttggtactgt gtcaaccatt atttcaacac cattatacct agcctttaat atctcatcaa
     1141 atgcttctat ttcaactgga cttaagtgag atacttgaac cctagcacca cttttttgcc
     1201 caacctctat ggcttctttt actgcattat atcttcctat gtaatctcta atatgagatg
     1261 tatatatacc atcatgctct ttaatctgcc ttgcaatatc aacaagttca tcaatatcag
     1321 catacttact tggtatatat gccaatccag tagatattcc aaaagcacca cttttcattc
     1381 catcatttat tatatctgta atttcatttt tttccttttc tgtaggaggt ctatccttag
     1441 aacctcccat aacactccat cttatagtcc catgccccaa caagaatccc atattgacag
     1501 aaataccact tttagatata aggtcgcaat attctgcaaa attattccaa catttatttt
     1561 tatctataag atactttttt tcttcttcaa gtaatagacc atttttatac atatattcat
     1621 atacattttc agaagaatat ggtgttatag aatgtccaca attaccattt atagttgttg
     1681 taactccttg ttttagaaac ttttcaaatt taccatctag tattgctact atttcttcat
     1741 gaacatgagg gtcaataaat ccaggtgtta taacttttcc acaacaatca atctctttat
     1801 ttgtattgct atttatctta gaatctattt ttgctattaa gttgtcttta attgctatat
     1861 ctccataaaa accaggatta cctgtaccat ctattataaa tccatttttt aagattaaat
     1921 catatatcaa aatattccct ccttaaaaac caatttttaa ataatcttaa tgtaattttt
     1981 atatttgaaa atcaaattat tatatttcat atttgaaaat tcactattat ttcattgtaa
     2041 ttattcacta agcttatctt tatacatagc tcttgcaatt aatatagtac caaatacaca
     2101 tataagaact actagagact gtggtattat accttgcttt gataatataa tagtcaatac
     2161 agatattaca attgctacta gacctaattt tttatcttgt aaaaatactt gtccaaaaac
     2221 tgacccaaat agagctggta aaattaagtt taatttttct actacttcag ctggaatttt
     2281 agataatacg cttcctccta aaattacccc tatagttagt atacttatat tcactaaaat
     2341 agatacagct attcctattg tagatattat cgagccttct tctgtacctg attcaacttc
     2401 tgctgccttt tgagctgcta ttgaacatgg tagcctcata ttagatatat taccagaaag
     2461 aaaactcata taagttcctg ggatacctaa gattggtgaa taagaaactg gttctattat
     2521 gtaatttgga gcactcatac tgacaattgc cattgtactt gctaataatg ctgatattgg
     2581 aggcataata ccaaatccaa agctcaaaat tattccagga actaatgctg ctataatacc
     2641 caaagatagt gttagtcttc catatcttat cataaaaggt aaatattctt cattgtatat
     2701 agattttact ttactcataa aactcccccc ttatattact gaagctatta tcattccgct
     2761 aaacattgat attgtaagcc cccactctct taaccatttt atatttttct tcttttcaag
     2821 catacacaat attaccatta tagccattcc acttatacat gcaattgttc cattatcaaa
     2881 acgcaacacc ctatcagcat ttagatatgc aaatgaaccc aacattgctc ctagagatat
     2941 tattggtata aatgatttct tgccactaga tataacattg gttatcttat ctagtttatg
     3001 tccaaatagt aatgtgaata ttatccatcc taaagaacct aatatcatag tccaaactgc
     3061 atttgtaaat gcaagttttg tcatttcagg agaacctaaa gttataccta atgcatctgt
     3121 tccaaatccg gctgacattg attcaaaaat tacagaacct ataaatgata atctcatcca
     3181 tgctataggc ccacccatag ttactataag cgataccatt ccagcaaata tagtcattga
     3241 aggcccaata gctgaaatag cactactctt aacagctgac tttatttgtt tatctgttat
     3301 tcccattgtt ttaccaactt tgcaagattt tatagcaaat ataagggatt gtaccactac
     3361 tattgatact gctactgtac tcgctatcca caaaagtgga tgattagcta attttaaata
     3421 atccatttat aaaacctccc tataaatcct caaattttat taatatttct aatatatcta
     3481 tttccaaacc tgttttagta ctctaagtat atttccacct agtaccttct ctatttcctc
     3541 atcactatat ccatgcttta ctaaatatct gacaatgttt tttgaagttt ctgttgggtt
     3601 ctcaagacct tttacatatt ctactttggg atgttctttt gtacctgtta ttttttttat
     3661 atcaaattta gcagctagta ctgagtgtaa ttttacatgg tcgccatata ctgtatctgg
     3721 tccaaaagct acatggtcta ttcctactaa atttttaata tactcaaaat gttccataaa
     3781 tgactctatt gaatgttctt tattcttctc tgttattgta gtatgaggtg ctgcttctac
     3841 acctataacc cctccttttt tagcacatgc tattaatact tcatctggag ttagtctctt
     3901 tgtgttccat aaacttcttg ccccaacatg gcttaatatt attgggtcct tgctatattc
     3961 tattacatca agtgtagttt gaactccaac gtgagagcaa tctattgcca ttccaatttt
     4021 attcattctt tcaacagctt tttttccgaa atttgtaaga cctccatctt tctcttcttt
     4081 tagtcctgaa cctaatgcat tggattcgct gtatgttata cccattaacc ttataccaaa
     4141 tccatacagt atatctattc tatcaagttc attttctatt ggtgctgcac cttctaatgt
     4201 tggtatcaat gctactttac cttcactttt agctctgtat atatcttcta ctttttcaca
     4261 ctttatgaca aaatcttgat gagctaaatc acatagtctc atgcctaaat ctattaatat
     4321 atcatcccat ttccaccctg aatttgatgt tatcgtacat acaccatcca ttaaattatc
     4381 aaatatagca tcataatatc ctcttgataa tgcttcataa gcgcatcttt gtttaccttc
     4441 cctattatat tcaaatatat ctctttctag gtgttctgga aataatactg gatgttcatg
     4501 taatgatata aatatttttt catccactat acttttaacc ttagcttctt gaatatcatc
     4561 taattcaata aggtactctt taactctttt atctccttta cacatctcaa tagatgaaat
     4621 atcttttcct ttttctaaat aactataggc ttcatatcct ttgtaagctg acttcataac
     4681 aacaccctcc aagttctaca attttttata tttttcctat gtagcaattg atgtgccaaa
     4741 atataaattt taattgtata ataaatcttg caaaaaataa aaacagtagt aaggttgata
     4801 tttactactg ttttattaaa aataatcttc ttagattatt tattcaatat ttttgaatta
     4861 tcttaatctt aaagataatt ttatttattt ctatctatta tagggatttt tttagggtgt
     4921 tttgcctttt tggtccccta tatcactccc ttaattttta catatgatat aaagttcttt
     4981 ccttcatcag ttataaaact accttgtttt tttactccag ataaaagtaa accatggctc
     5041 tttaacttat ctattctttt tctaatttgg tctacactta aaactatatc tttttctttt
     5101 aaaatctctt gcagtttatt tcttcctaat aatatatttt tattattcca agtttctata
     5161 ctggtcaata tacatatact ttcctcaaag aaattagatt gtttgaaatc taagataatt
     5221 gaatcgaaat tttcattaac taaagtattg tttttttcaa atctaaattg ttctggcaaa
     5281 tgctcgtaat ctactctatc ttcctcaact atagtatcaa tataataaat taaattttta
     5341 agctctctta catttcctgg ccattcatac aatgttaaag cttgcattga ttcctctgta
     5401 aaacatttgt tgctatttat ttcatctaaa aaatacttac ttataagagg tatatcttcc
     5461 ttacgttctc taagtctagg tatctctata tgtaatacat taatcctata atacaaatct
     5521 tctctaaaag aaccttcttt aatttttttc tttaaatctt tatttgttgc agctataatt
     5581 ctaacatcta ttggtataat tttacttccg cccattctca taacttcttt ttcctgtaat
     5641 actcttagca atctctgctg tacatctaaa gatatatcac ctatctcatc taaaaaaatt
     5701 gttcctgtat gtgctctttc aaatatacct atttttccac cttttattgc tcctgtaaaa
     5761 cttccttcat catagccaaa aagttcactt tcaataagtg tatctgacaa agaagataga
     5821 ttaactgcaa caaatggctt gttttttctt agagattcat tatgtattgc ctgggcaaat
     5881 atttcttttc ctgttccatt ttctccaagt atcaacacag aaaaatctgt agttgctatt
     5941 tttcttgcaa tattaatttt ttcttttatt attttactct cacctacaac actctcaaat
     6001 gtatactttg atacaaaacc ttttgactga agtttatttt gaatcttgtc ctcaagcact
     6061 tgaattgcac ttatattttt aatgcttata atactcttta ttcgttcatt attttcataa
     6121 acatttactt tattaattat cagttttttg ttatttaaat ttactacttc atcattaact
     6181 tcatcttctt gaaaaaatat ttttttgaca accttatcac taaataagtc cataaagtta
     6241 ttagatataa tttcattttg gtctattcca actagattag aaaatacttt gttgcaatat
     6301 ataaattttc ctaatttatc aacagaagca ataccttcat ctataatctc caaaaaactc
     6361 ttcatggttt tattcatagt tgtataatac ctatatccac ttactgtatc ttcattgtat
     6421 ttttccttaa taatatgtaa tttatctata gatatattta gttttgtaaa gatttctata
     6481 actgtattta tatcaattac cttatcacct atgtcaatta tttgctttat gttttgtggt
     6541 atgctgtttc tgcttcccgt aataattcca atctcacatt tagacttatc acaacctgga
     6601 taatatggta ttagattaat atgaattaat cctagttttc taattatctt ggcagtttca
     6661 tctgctgact ctttataagc atctataacc ataacatcag aatcattttc tatacttatt
     6721 atctgattta tattttcaat atttatagta cgatgtacta ttacaatagg tatattttta
     6781 tcaatattat tatgtatata ttcctttata tcattgtctg aacatactac aagctcatag
     6841 cttgacagtt caatatttat cctatttaca tataccaagt tatctatatt acaaaattct
     6901 ccaaatatat tttccaattg ttttgatata tctatattta ttttgtcatc agttgataca
     6961 aataaaatat tatgtttttt catagtccca cctcctgttt aacgagtata gaaagtaata
     7021 atttggtcta ttgtagcact ttttaaaaaa gttttaaatc ttaaaaatca aattttgtac
     7081 catttactat tattttccat actaaaataa tgtaagctat cttttttcac atataattta
     7141 atttctaaaa cggttagttt gacattattg gaatataaac aaaaatttaa tataaattcg
     7201 ttaatatatt aatacatttt taagaatgat aaggaataaa ttataacaaa ttttaggaat
     7261 atataataat agggtctcag aacttagtta caagttctaa aaccctattt gtttagtgta
     7321 aaaaacatca taaaatttag cttaaatctt ttcacataat attactcttt ttctaagtga
     7381 taataaaata tatctattcc tctaaaaact gtaaaaattc ctgattaaat agtttaagct
     7441 catcatagaa tatagcatga ccactatact caaaagtata taaaattgaa tcttctattt
     7501 tttcattcat aaaaactgca aattcatacg gacatatttc atctaatttc ccatgaaata
     7561 taccagtagg cactcttaca cattttaaat cattaaataa ttcttcatct cttaaagata
     7621 cagcagttcc aatagtgcca atacctgatg cactaaaacc aatatcatta aaccatcttc
     7681 taaagctttc tggtggattt gatgcaaata ctttttcgcc aaaatcgttt accatttctg
     7741 gtctatcagt acatgcttgt gctatcaatt tatttacatc ttcacgtgtc ataccatatg
     7801 gaaattctgg aggtctttgt acaaatgatg gtgcagcagc tgcagctaat accaattttg
     7861 acactccata tccattaaat aaactcatat acctaagtac gattgctcct cccattgaaa
     7921 aaccaacaag ggtaaagtct tttaatccaa tagcatgtac caccttataa atatcgtctg
     7981 ctaattggct ataagtatat cctcctgatg ttgcatcaga tttaccaaaa cctcttaaat
     8041 caattgaaac tgttctatat ccgagttttg gcaatatatt tgtttgatat tcaaatatct
     8101 tatgtcctaa gggccaacca tgtataaaaa gtacagtttt tttagcactc ggattcaaat
     8161 catatactgc tatgtttata tcattaacat atacataata catatcaaca gcaactccct
     8221 tcaagaaaat gtatgatggt tattttatat atatgaataa aatgatgaat aactaaattt
     8281 tcaaatttat ttacaatact tctctattgc cttttcaaat aaacttacat gaagtttttc
     8341 atctaggatt attctattta atatagcttt tatataaggg tcttcaataa gacttatatc
     8401 tttataataa ttattaatag ccacatgctc caaatgcaaa tctagtttta atctgttaca
     8461 aatagaattt ccataacata caaaaccacc attccaatat gcaccacaag aacttgtaga
     8521 acctctatat acaggatttc cacccaataa tcttatagtc tttgctaata tctccatatg
     8581 taacatttct gttatagata tatttatcca catttcactt aactctctat gcgtttcatc
     8641 taaatcaaaa ttatggtata gatattgatt tacactcgta aattcacttg atactccggc
     8701 atagtcatcc atcaataatt ctgcataata cttatttgga cctaaaactt ttatctctgg
     8761 atatggctca tcacttgaat atccatttcg cttgtgcatg tcataatgtg catcactcat
     8821 aatatctcct cctttaaatt taatacatga tattaattgt atgcatcacg actttttcat
     8881 ataacttaga taataaaatc tacttaaata ataaaaagcc atattaatta aaattaacat
     8941 gaccttttat ccacaaaatt actttttaat tattcatctt ttccagctac tgatagctct
     9001 ttaataacaa ctgaaggtga acctatacta ctcattggaa attctaaatc ttcccctata
     9061 gcttcaatat ctttcaacag gtcaaaatag tttcctgcta ctgtaatttg ctccactgga
     9121 aatacttttt ttccttcttt aatataaaag cctttagcag ctaaagaaaa gtctcctgtt
     9181 actgaatttg cacctgaatg aagtcctgca aagctagtaa ccatcaatcc ttcatctata
     9241 tcctttataa tttcatctaa agatttatct cctttctcta tataaaaatt agttggatat
     9301 atgcttatag gtgatgaata tgaagatttt attccatttc ctgtagtctt tacacctgcc
     9361 ttattagccg tttttaagtt atgaagtaaa gttataagct ttccatttaa aacaacttct
     9421 tttttaaatg tagctactcc ttcatcatca aaaggagtag atgccatacc attttctaaa
     9481 agtgggtcat caactattgt aactatagga gatgctatca tgtctccttc tctatttttc
     9541 aataaagata atcctttttg agctgaatct gcattaaata tcccagaaaa tgtgctaagc
     9601 aaagatacca tagcttcatt aagcaatata gttttatatt tacctgatgg aatactctta
     9661 ccacctactt tagataaagc attatcaaca ccaagttttg atatctcaca aggttttatt
     9721 tcttcaatag aatttgctat attatatcct attccatcat atttttgtcc attgtcttct
     9781 atgataggaa ctacaaaccc tataagcata ttagttttat tgcttaaatt aagaccttta
     9841 gtattagata taccattact tgatacagaa taagatatag tacatttaga taaatttacc
     9901 accttatctg aataagcttt agtctctctt tccatttcta aagctaaatc aatcaactta
     9961 tctgcctcta aattttctag ctctttagaa taagtcttta catcattata gtgcttatct
    10021 ccttcatata taaattgtac atcttcattt tcaatagtgt ttactccatc ttttacattt
    10081 tttatcaaca tatcaacagc tttatcatct aaaatttctg tataagaata acctatcttt
    10141 ccatttacct tacctctaaa agataaacca aaagatttat caagattgta tttctcaact
    10201 tctccttcat atatatttat acttaaattt tctcctgtat aataatatat ttcacactct
    10261 tcaaaacctt cacttagagc ctttttaaat aatatatctt taaaattttt aagttccaca
    10321 attatccctc ctatcttcca cctacagtaa tttcttttac ccttatcata ggttggccta
    10381 cattagttgg tatacttcct gatgatgagc cacacatccc ctgagcttgt tttacgttat
    10441 tcccaaccat atctatattc ataagtatat cgctaccttt tccaattaaa ctagcacctc
    10501 tcactggctc ttgtatttct ccatttttta ttaagtaacc ttctgaaact gcaaaattaa
    10561 actctcctgt tacaggattt acagaaccac cacccatttt tttagcataa agtccatctg
    10621 gtattgactt tataatgtct tctggtctat cttctccagc agcaatataa gtgttagtca
    10681 tccttgaagt tggtgcaaat ttgtagttct gtctacgaga acttcctgta ggattcattc
    10741 ccattcgtct accattaagt ttatctatca tataagactt caaaattcca ttttcaatca
    10801 gtatattctt ttgagttgga tttccttcat catctatatt catagaaccc cagtagtttg
    10861 gtattgtacc atcatctata gctgtaatct ttgtggaagc aatctgttga cctaatttat
    10921 ctgcaaatac agagttcccc tttgcaactg atgtagcttc caaagaatgt ccacaagctt
    10981 catgaaatat tactccacca aatccattat ctattgctac catcatatta cctgcaggac
    11041 aatttttagc atgcaacata gtatgcgcta ctctagctga ttcttttgca taatattctg
    11101 gatctatttc ttcaaatatt tcaaaccctt tacaacctcc aggaccttca aatccagttt
    11161 gattttcatt gcccttagat gcaattgaac ttatccccag tctggttctt attcttctat
    11221 cctcaacata tataccttca gtgtttgcaa ttaatatttt ttggtcttta tccaaatagc
    11281 taacacttac ttgagatata tcattactaa attcttttgc actcttatat gcaaccttca
    11341 tagcacttac tttatctcta tttcctattg aatttggata aatttttata ttatgtatgt
    11401 tatttatttt aatactgtca tttaatatta cactttttcc atcttccaat ttccctaaag
    11461 caacagcagc tttgtatgct acatccaaca gactatttaa tgaattgtca cttgtataag
    11521 catatatact tttcaatcct ttaaatattc ttattcctat accataattt cttccaccta
    11581 ttgcattttc tactttatta tctattaaac taatagaatt atttatagtg tcttcttcaa
    11641 aaatctcagc aaaatctcct ccagtaatta gacacttttc taatacctta gaagctatat
    11701 tttttgaaag cataaattta cctcctactt taaattttta attaactttt attcaatctt
    11761 tttacttgtt aacaaacatt atatactata ttacttaaaa taaggtaatt atgaatatat
    11821 tatacatatg ttttatacta aaatgttatc acattttatc tatacatacc catataacta
    11881 gataattaaa atgtataata ttatttgcta tagaaaataa tacactcata cataataaat
    11941 tttaggagtg aagtatatga atcaagaata tgtaaaagga aatcctattt ttactaatat
    12001 taataaagtt ccaagacaat ttccatacct tactgatgat attgatactg atgttataat
    12061 tgttggtggt ggcgtaactg gatgtatttg tgcttactat ctagctaaaa acaatataaa
    12121 gtctgtcatt cttgaaaaag gaaggattgc acatggaagc actagcgtga caacttctct
    12181 attacagtat gaattagatg acaatttgat agatttaaca gaggttatga ctctaaaaga
    12241 tgctctaaaa gcatataacc tttgtacttc agcacttgaa gaattagata catttataga
    12301 gctatatgga aataagtgtg attatgccaa aagagatact ctactttata ctgccaacaa
    12361 acttgaagtt aaggctatca aagaagaata taacttaaga aaagaaaatg gatttgatgt
    12421 tgaatatatt gatgaatcca caaacccttt tagctttgat ttaaaatcag gattgatagc
    12481 aaagaatgga ggacgagaat tagacccata taaatatagt caccatttga ttgatgtaag
    12541 tttaaaaaat ggtcttcaag tatatgaaaa tacagaagta aaaaaagtag atttatcaaa
    12601 tgataaggtt actgctgaag tatcgtatgg atacaaagtt catggtaaaa aattaattgt
    12661 agctacaggg tacaatacaa gtttatttac aaaaagaaat tttgcaacta agtcaaatac
    12721 ttttaatata gcaactaaac cacttaaaaa catagcttct tggaaaaaca acattttaat
    12781 tagagataac tgtgacccat ataattatct aagaactact aaagacaatc gattaattat
    12841 aggtggtgaa gatgtaagtt ttgatgatat agaaaatgaa actttagcca atgaaaagta
    12901 tgatatttta gaacaaagat tgaaaagtat gtttaaggat ataaaagaca ttgaagttga
    12961 atataaatat tgtggttgtt ttgcttcaac tttagataat ttaggtttta ttggtccaga
    13021 taataaaaat aacaatctat ggtattgctt aggttatgga gcaaatggta tactctttgc
    13081 aatattagga ggtataatgt taagtgaatt atatcttggc aaacaaaata aaaatatgaa
    13141 attatttaaa gtagatagat ttgataaata gatattgtat attaaaagac tgtaaaaaga
    13201 tgaaactttc taattctaaa agttaacttt gatacagtct tttataatgt tccttttaaa
    13261 aatactttat ttataattaa atataaagta aaatgttaaa atataactga taaaatttag
    13321 tcataagata atatttaagt ttatttgatg aaatatggag gaattattat gaaagaaata
    13381 ctcgttattg ctcccactaa aggaacctat gaaaaatcaa ttcacatagt taaaaaaaac
    13441 aaatatacaa atattgatgt tgtatttggc aatctaaaag aaggtatacc tcttgctgaa
    13501 aaaagtatta atcatggtac tagaattatc ataagcagag gtggaactta caatatgtta
    13561 aaagctactt acaatatacc tatagttgaa attaaagtag atgcttatga tattataaaa
    13621 agttacaaag aggtaaaaaa ttccaacgaa ccatttggaa taattggatt taataatgtc
    13681 atctacggtt tcgatattat agaagaaata ttgaataaga aaataactat gattgaaatt
    13741 gaaaaagaag aagaaattta tgatgctata gaaaagtaca gaaagaaagg tataaacaca
    13801 tatataggag ataccactgt tgcacatatt gttaagagac ttaattgtaa gggaatatta
    13861 atcgaatcta gagaagaaaa catacttaga gccattcaac aagcagaaca aatactcgaa
    13921 gcaaccaagg atgaacaaaa aagaagatta cagatagaag ctatgacaga ttttgtacat
    13981 gatggaataa taacagttga taaaaatttt aaaataacat tatttaataa gagtgctgaa
    14041 aaaatatttg gtataaaaaa agaaaatgca ctttatcata atgttgtaga tgttatccca
    14101 aacacagttc ttccacaagt agttgagact atggaacctc aaattggtga aatacaaaat
    14161 atagggagta caaaaattat tacaaataga gttccaatca ttgttgatgg tcagattcaa
    14221 ggagctgttt caacatttca agatagcaag gagataagtt cttttgaaca tacaataaga
    14281 aggagcttat taagcaaagg tctatctgct aaatacactt ttgatgatat aattcatgct
    14341 agtgaaaaga caaaagattg tatagaactt gcaaaaaaat atgcttgtta tgatactcct
    14401 atgattatta ctggagaatc tggagttggt aaagaactat tttgtcaaag tatacataac
    14461 tatagtaagc gtaaaaatgc accttttgtt gctgtaaatt gtgctgccat acctccatct
    14521 ctaatagaga gtgagttttt tggttatgag gaaggttcat ttacaggtgc tagaaaaaaa
    14581 ggtaaagcag gtgtattcga actagcacat gaaggcacaa tcttcctaga cgaaataagt
    14641 gaaatccctc ttgaacttca aggtcgatta ttgagggtat tgcaggaaaa acaagttatg
    14701 agaattggtg gtgataaagt tattcctata gatgtaaaaa ttatctgtgc ttcaaataaa
    14761 gacttaaaaa atatgatgcg caatggttta tttagacaag acctttattt tagaataaat
    14821 atactaacat tatatcttcc ttcattaaaa gaaagaaaag aagatattat aaaattatca
    14881 gaatttttta tacataaata ttcaagcaaa tacaataaaa cgcctttaat tatcactcca
    14941 aatattaaaa aggcacttct tgaacgagaa tatgaaggta atataaggga attggaaggt
    15001 atgatggaaa gggctgttat tgtggaatca tttgactcga ttttattaga aaaggttagc
    15061 aatgaatata caaataatat agttgataaa gataatagtg attttaaatg cagtaattta
    15121 gatttaaaaa ctttagaaaa aaaatatatc tataaaattt ataacgaaaa taatagaaat
    15181 actacaaaaa cctgtgaaat tctaaagata actcgctcca ctctatggcg taagttaaaa
    15241 gaaatagaaa atgatgttta aaaataatac atacctatat atatcaaaac gttttatgtt
    15301 taattttaat acataagacg tttatttgtt ttcaataaaa aatacaatta tatgataaaa
    15361 agaatctttg taagtgaaat tctcatcaat cataccttta attataagta atctacagca
    15421 tttcaatcga ttattaaaaa taatcatgat aactaaaaat acaaactcta tatattggca
    15481 tagtaattgc ttttataata cctatataaa aatgaaaggg agtgatacta gatgcacatc
    15541 ttaaaatcag tgaaaaagat accaggagga cttatggtct gtcccttgtt attgggagca
    15601 ctatttaata cagtatgtcc acaagctctt gaaattggag gattcacaac atccttattt
    15661 aaaactggtg caatgagtat acttgctcta ttttgtctat gcaatggagc tcaaatcaat
    15721 atcaggcaag ctggtaagcc attgactaaa ggtatagtac ttacagcaac aaaatttata
    15781 attggtgcag tattaggtat tattgttagt aaatttattg gacctaaagg tataattggt
    15841 attacacctc ttgccatagt tgctaccatg actaattcaa atggaggtct atttgctgct
    15901 cttgcaggtg aatatggaga ctccacagat gttggagcaa tatctatctt atctctaaat
    15961 gatggtcctt tttttacaat gcttgctttt ggagtaactg gacttgcaaa tgtacctata
    16021 gtagcactat ttgcagcact tataccaata ctacttggat ttatacttgg taaccttgat
    16081 gaagatatac gagaatttct tgcacctggt acaacattat taattccttt cttcgctttt
    16141 cctttaggag cagcattaaa ctttaatcaa attataactg ctggactacc tggagttgta
    16201 cttggtttag gagttactat aataacaggt atgggtggct actttgtaat gaaacttata
    16261 cgtgcagaac atccagcagt aggtgcagct acaggtacaa cagccggaaa tgcagctggt
    16321 actcctgaag ctttagcagc tatagaccct actctagcta caatagcagc tgtttcaaca
    16381 gtacaggttg ctgctgctat tattgttaca gcaatatgtt gtccaatgtt agtttcctat
    16441 ctagataaaa gagaaaaaaa gaaaaaatct atttttaaaa caaataaaaa tattgaagta
    16501 aattaatact taaggaggta aaattaatga atgcaattat tcatgcaaat gaaaaagata
    16561 atctagttac atgtgtcaga cctttagtta aaggtgaaaa agtttcaatt gatggaaagt
    16621 cttacatagt aaatgataat atacctgtct ttcataagat ggctacagaa gatgtaaaaa
    16681 aaggtgatgt tgtatacaaa tacggtgaaa ttataggaat tgcaacagtt gacataaaaa
    16741 ctggtgacta tgttcatgta cataacattg aaagtacacg tggtcgtgga gataaaaaat
    16801 aggaggaagt taaaatgaaa ttaatgggtt atttaagaga aaatggtcag tttggtattc
    16861 gtaatcatgt tttaattatt ccaacatctg tatgttcaag tgagacagct acaagaatag
    16921 catcacttgt gcctggagca atagcaatcc ctcatcaaca tggatgttgt caaattggtt
    16981 ctgatataga gcttacagca aagacattaa taggatttgg aaaaaatcct aatgttgccg
    17041 cagttttagt agttggtctt ggatgtgatg gtattcaagc aaaagaatta gcatctgaaa
    17101 tagctacaac aggaaaaaag gtagattacg ttgttataca agaatgtggt ggaacattaa
    17161 aaacagtttc taagggaact gaaatagtaa gtaaaatggc tcgtgaagta tcaaaagaag
    17221 taagagttga atttggtatg agtgaaatta cattagcact tgaatgtggt ggttctgacc
    17281 caacaagtgg aatagcttca aacccttcaa taggcgttgc atcaaacctt cttgtagatg
    17341 aaggtggaag tagcatacta agtgagacta cagaagtaat tggtgcagaa catttgttgg
    17401 ctacccgttt tgaagatgaa gaaatgaaag ataagtttct taaatttgta agtgatgtag
    17461 aaaaaagagc aattgctatg ggagaagatt tacgtagtgg tcaacctact ccaggtaata
    17521 aagctggtgg actttcaaca attgaagaaa aatcacttgg gtgtatgtat aaggcaggca
    17581 ataagccatt caaaggtgct cttgaatatg ctgatattgt acctcctgat aaaaaaggat
    17641 tatattttat ggatactcca ggtcaagata tagattctat cactggtatg gtagcaggtg
    17701 gtgcacaaat tgtaatcttt tcaactggta gaggtactcc aacaggaagc cctatttcac
    17761 cagttattaa aatcactggg aatagtgata catacaacaa aatgccagac aatatcgata
    17821 taaatgcagg tagaattata acagatggtg ctaaaatagc agatataggt caagaaatat
    17881 ttaatgaaat aatagaagtc tgtaatggta aacataccaa agctgaaagt cttggtcata
    17941 gagaatttgg catttacaga atttcatcta cattttagat tgtaacaaaa tatcttttat
    18001 aaatataata cttatgtaga tacataagct aaaagttctt tctaatccta taaaaatttt
    18061 ctatactgaa aaggaactgt atcaaaatta ttttgaaaac agttcctttt ttaacctctt
    18121 ttactcaaaa tattataaaa taagatttaa acaataaacg tgtcttgatt aatctctaag
    18181 aagacataaa taaagctaaa tgtaaagtga gataaataaa atttaatatc tttgtatgaa
    18241 aagatatttg gtataatatg tctgagagaa ttcttatttg taaacaaata aaggatggag
    18301 gatgaaacaa aagaatgaac tttgaaaaca caaaaaataa aaaaataata gctactttac
    18361 tattgacact ccttttaatc gtgtcattaa catgtgtcac ttttattatg aatctaaata
    18421 aagtaacaca taatgaaaca gaacgatatc ttgtagaagt ttcacaaagt atttccacta
    18481 caattaatgt gaaatgtaaa agtatattta ggacactata ttctatggga gatacttatt
    18541 ttgagattaa tgatagtgaa aaagaagtca atagatactt atcaaaaaaa ttaaaattat
    18601 ttgaatttga ttggttaggt attatagatt ctaatggaaa ttttgtaagt gcccttaaag
    18661 atacaggtaa tgttaaagga caagactttt atagaaaagc ccttcaaggt aaagaaacaa
    18721 ttactcctgt taaatcacaa tctggtacat atggaatttt atattctgta ccactataca
    18781 atggcgataa aattgttgga gctgttgctg cttggaatac tattgatact atgagaaatt
    18841 tattaagtgt agaaagcttt catggtgaag gattttccca aattatcgac caagatggaa
    18901 attttattgt aagttcagca aacaaaaatg ctccaaaaaa tgtggtaaat ttttttgaca
    18961 tgattaaaca ccaaggaaaa caggttgata aaaataaact tgaagaaatg aaaataaact
    19021 taaaaaagaa caaaactggt tctatgtatt atacattaaa tgatggtatt tctaaggcaa
    19081 tgcattatct tccattacaa gaagaaaact tatacctcct ttcagttgtt ccaacaaaaa
    19141 cagcaagtgc acagtttgat ttacttctaa aaaaagcaat cttcatcaat attttaattg
    19201 ttatactatt tttattgctt attatattga ttatgtttat aaatcaaaag aacagggcac
    19261 aacttataaa aatcgcctat gtagactctg taactaaagg ttacagtaaa gcacgttttg
    19321 atattgaagc taaaaaaatt atacagtcat cttcatcaga aagctattca ttggtatcta
    19381 taaatattca gaaattcaaa cttattaatg attcttttgg tagtgaagca ggagataaaa
    19441 cattaaagta catacatgat gtcattagta attatctaga accaggagaa ttgctttgtc
    19501 gagtttctaa tgaccagttt aatgtactta ttaaaactat tcctcaaaaa gaaattctta
    19561 agtacataga aaatatcacc aatgatatta atagtttcaa taaaaatgaa gaatgtaaat
    19621 attttatagc tctatctata ggtgtatata aaattgatga cccaaatcta cctttagttt
    19681 caattcaaga ccgtgcaaat gttgcacgaa aaaataataa aggaaacatt ggaaatcatc
    19741 cactttatac atgtgttttt tatagtgatt tagagcgttt aaaaatgatt aaagaaaaag
    19801 aaatggaaaa tagaatggag gaagcattaa ataataacga atttatagta tatcttcagc
    19861 ctaaaataag cctcaaagat aatactattg taggtgcaga agcattagta agatggcaag
    19921 acccaaataa aggccttata ccaccagacg agtttattcc tttctttgaa aaaaatggtt
    19981 ttattacaaa actcgaccac tatgtttttg aaaaagtatg tagtatgata agaaaatgga
    20041 tagataatgg agaaactcca atgcctgttt cagttaattt ttcacgtgct aatttaaata
    20101 atatagattt tttagaaaaa tacagaatgc ttcgtaataa atacaacatt cctgctaagc
    20161 tcttagaaat tgaattaact gaaacacttg tatttgaaaa tctccaaaaa ttaattaata
    20221 taatagacca aatccatgaa gaaggttttc aatgttcact agatgacttt ggaagtggat
    20281 actcttcact caatatgtta aaagaaataa aagttgacac attaaaactt gaccgtgctt
    20341 tttttagctc acctaatgca gataatattg ctgaaaatca tgtaatagaa tctatagtta
    20401 atttggcaaa aaaattaaat atgaatagta tatcagaagg tgttgaaaca atcttacaaa
    20461 tggattatct taaaaaaatt aattgtgata tgatacaagg atatgttttt tcaaaacctc
    20521 tgcctcaaga aatatttgag aaaatgactt ttggaaaaaa actagaagaa accagtatgg
    20581 atagttccgt ttaaataaaa taaaaaactt gtctctataa aataatttta atcattttat
    20641 aaagacaagt ctttttattt tccaatttaa ttttattttc taaatttctt atactcggct
    20701 tgttttaaat tcccttttta agaataataa tacgattatc atagcaataa aatctgcaac
    20761 tggctgtgcc aaccaaacac catctaaatt aaattgaatt ggaagtacaa tgattaatgg
    20821 tataaataaa ataaattgtc ttaaaagagt taaaaacatt gaatgtttaa ctttacttat
    20881 acactgaaaa tacacaggtc ctacaataga aatccccatt ataggcaatg taattagatt
    20941 tatgcttata cctcttactg ctatatccat caaatctgaa tctttattaa atatacctac
    21001 aaatacttct gggaaaactt gtactactaa aaatccaaat gacaatatga caactgacac
    21061 tatgatagat aatattaaag ttttctttgc acgttcatat tgttttgcac cataattgta
    21121 tgatattata gtttgcatac cttgattcaa tccaaacaca ggcatcataa acatcaataa
    21181 aatagatgta agtgctgtca tagctccaat agctaaatct ccaccataaa cctttagaga
    21241 attatttgta aacatgtgag ttatacttat agctacttcc atagcaaaag gtgtcattcc
    21301 tattgcaaat accttcttta ctatatcttt attcaatttt aagttacatt tttttagttt
    21361 taaattggac ttccctctta taaaataatg tattacccaa aagaatacta ctatttgaca
    21421 gagtactgtt gctatagctg ctccttttat acctaaatta aatacaaata taaatatagg
    21481 gtccaatatc aggtttaata cacatcctac aatcattgtc cttgctgcta attttggatt
    21541 accttctgcc ctaattgcat tattaagaga aaatgcaact aaattaaata tacttccaat
    21601 caatataaca ctcatatagt cttttgcata aaatattgaa tctttacttg cacccaaaat
    21661 aaaaagtata tcttctaaga aaactaaccc tgatatagtt ataattaaag agataattat
    21721 agataatgtc aaagcattac ctaatatctt ctctgcttct tctctatttc tttcccctaa
    21781 ctttatagac aatcttgtgc tagcacctac tgataccaac attccaaaag ctattattag
    21841 agtaaatact ggcatagtta caccaagacc tgcaatagct atagagccaa taccttccat
    21901 agaaccaata aaagctctat ctactacatt ataaagtgaa gttaccatca ttgctattat
    21961 tgcaggtatc gaatacctaa ataataaaat ccatattttt tcatgtctta atgcttcttg
    22021 attctccatg ttgtcaccat ttacaccatg tcataagtta tacaaattgg tttatttgtt
    22081 cttgggtctg ttgctatttc tgcatcaata ttaaataatt cttttagatt atccttcgtc
    22141 ataacatcat atgcatcacc ttcacaaact attttacctt tcttaatacc tatcatgtgg
    22201 tcagcaaatc ttgctgcatt attaagttca tgtattacca tgacaatagt tcttccttgt
    22261 tttttattta gttcatctaa taattttagt atctctaatt gatgtgccaa atctaaatat
    22321 gttgtaggct catccagtaa taatatatca gtttcttgtg ccaaagccat agctatccat
    22381 gccctttgtc tttgtcctcc tgataaatct tccatatttc tatccttaaa ttctgcaatt
    22441 ccagtaactt ctaaactcca atttacaatc tctctgtctt ctttactaga attaccaaat
    22501 ccacttttat gaggaaatct tccataagaa attaattctg aaacggtaag accactagga
    22561 gcttgaggac tttgtggaag tacagccata tcctttgcta tttctttaga cttctttttg
    22621 tagatgtcct ctccatttat atatattttc ccactattag ggctaataat tctacctata
    22681 gttttaagta ttgtcgattt tccacaacca ttagccccta tgatggtagt tatttttcct
    22741 tttggtatat ttaaatttaa attttttata atatctgtat ttccatatga tacatttaga
    22801 ttcttagtat ttatacagtt cataacaaca ccctttccta atcatttacc aacattaaat
    22861 aaataaagta cggcactcct attatagaaa ctactatacc tactggtatt tctataggtg
    22921 ctagaagatt tcttgatata gtatctgcta ttaaaagtaa taatgttcct atcaatgctg
    22981 atactggtat taatctttta tgctttggtc ctattatttt tctacctata tgtggagcta
    23041 ttaaacctaa aaatgaaata ctacctgcta ctgctgtcga tacaccagat aaaattactg
    23101 catatattat aagtcttctt ctttgttttt ctacatctac accaagactt atagatactt
    23161 catcacccaa atttaaaaca tctatatatt tagatttata aatagttata cccataaaaa
    23221 tcactataaa tggaagcaca gctattacat atttccaact ggttccccaa atgcttcctg
    23281 atgtccatgc cataacccta ttaaattctt gtgttgtaaa tttcaattgg aatatcgtca
    23341 aaattgaagt aaaagctatg tttacaccta taccaataag tagtaatctt gacgaattta
    23401 taccaccttt ccatgcaaga gaatatataa gaaatgctcc aaataaagct cctataagtg
    23461 caacaatagg cattgtaaat acagtcaagt tactcatacc ttcatataca ttaccattca
    23521 taaggtatat ataaactact acaaacaatg cagcacctga atttattccc aaaattccag
    23581 aatcagctaa atcattcttt gtaactcctt gaagtattac acctgctgtt gataatgcag
    23641 aaccaaccaa aagtgctatt actattcttg gtaatcttaa tttaaatatt gcaatttcat
    23701 gattacgctg accctgccct aaaaaagtct ttataacatc cattggttct atagaaaatg
    23761 agcccatatt taaactcaat aaaaaagtga taaaaataag caccattaaa attgatataa
    23821 caagtaatgt tttagaattt atttttataa tatttttcat agtacctatt tctccccctt
    23881 tctaacaagg tatataaata ttggcactcc tataagtgct gttatagaac ctactggtgt
    23941 ctcatatgga ggatttatca tcctacttaa tatatctgta tatacaagca atacagctcc
    24001 taatactaaa gagctcggta ttatatactt ataatctgaa cctactattc ctttagctat
    24061 ttgaggaact ataagaccta taaaaataat attaccagac actgacacag atgctccagt
    24121 cattaatatt acaagtacta tacatataaa tctaacaaag ttagtttttt gtcctaatcc
    24181 tattgccact tcttctccaa gacttaatat agttattctt ggagccataa taatagctaa
    24241 aataaatcca ataccaccag ctacaaatag caattttata ccttcccact tcactcctac
    24301 aagccctcct gatatccaga aacttaattg ttgagatagg ttaaaataca tagatattgc
    24361 tgatgccaaa gaaattagca atgtaccaag agcgactcct gcaagagcta attttacatt
    24421 attaactctt cctcttgatt tagaacttat aaaatatata aataatccac ttatacttgc
    24481 tccaataaat gcaaacatca ttacactaaa acttccatgt ataagttgag gaagtttttt
    24541 ttgaagtacc agtgatatcg aaattgcgaa tgtagctcct tgtgtaattc ctataacaga
    24601 tggttcagct ataggatttc tcgttattcc ttgcattatt gccccagaaa ctgctaaaaa
    24661 ccctccaaca agtgcagctg ctattgctct tggaagtcta acatccttta ctattctcat
    24721 atttattcca tcttccattt ttatcaaact atctataaca gttgatagat tcatatcttt
    24781 tgccccaata gttatggata atacaattcc aaatacaagt acaactatac ttactaatat
    24841 caacaaataa gttatatttt ttttactcag cttagtcaat tatcctacct ccttttccct
    24901 tttaatcgtc agtataatat catctattaa gtattttaat tttaaaattt attaaaaata
    24961 ggtgtgaaaa atgaatatca ttatctcaca cctactaagt taagaattac tttgttaatt
    25021 catttttaac tgattctaat aataactctt ttccaattgg attgtatgat tgactgaaaa
    25081 atggagcagc atcaagtatt gttacattgc catcttttac tgctcttatt tgagcccaga
    25141 tagcactatt ttctaaatct tttttatctg cttctgtagc aattacaact atatggtctg
    25201 catctatatc tgttaaacct tccatactta ccattggtag tgttattcca tcctgttttg
    25261 gcatattctt aggtctatct aatttcatat catcattgat tagagtacct attccaccat
    25321 cactaaatac cataaattga cctgaacttg ccaacactgg taaataagtt ttttctccat
    25381 tcttttctat aacttcctta cctaactttg tagctttttc atcatacttc tgtagccaac
    25441 ttttagcttc ttcttctttg tcaaataact ttgaaacatc agttaacttg cttctccagt
    25501 catttgcata atctttcatc ataactacag gagctatttc ttttaattgg tcatatattt
    25561 tttcttgtct ttgactcatt attattaaat caggatttac ttctaatata gcttccatat
    25621 ccatagtatc catcattgag tgcccaacta tctttacacc tttaagctct tctcttatgt
    25681 aacttggtaa tttatcagtt tcatatgagt ctacatttgc tgttgcaaca ggcttataac
    25741 ctgctaataa tagttcttca ctacttcctg atatatcaac tattttttta ggatttgatg
    25801 gtatcttaac ctctccttta acagattgta caactcttgt ctctgattta tctttatcct
    25861 ctgtattctt atctgaacat gctgtaacaa gtactaacgt agttataata gatataaata
    25921 ttgcaagtga ttttattttt ttcatgatta cttctcctac ttgtttatta tacttacatg
    25981 atattgatta tcataagcac atatttatta tagcattttt ctatttttag tcaatattat
    26041 tttgtaaaag gataaaaatt cctaattaat cttaattata tatagcttag ataaggtttt
    26101 cttatattaa acagtatttt ttttaagaat tggacacaaa cacaatgact tttaggttaa
    26161 acaatgataa aatgcaattt atagataatg aatttagtag ggaggattca aaacatggta
    26221 catttagtat attgtgataa tgcaggaaaa aaaggagaaa aggtcttaga taaaatcttg
    26281 gctggaacaa aaacaatggt tattagaggt gctgctggta gaaaaatacc acatagtaga
    26341 gtatttgaag atgagttact ttattttatg gaaaaaggaa ctggaaaaat atctgcaaaa
    26401 gccactgtta aaaaggtaga aaactatgtt aaattaacag aagatgaaat ttctaaaatt
    26461 ttaaatgaaa atcaaccaaa attaaattta tctgaaaagc aaaaagttcg ttggcataaa
    26521 aaatgtttat gcttagttga atttgaaaat gttgaagaaa taacatctct tgattttgac
    26581 catcaaggaa atatggatga ttggcttatt gttgaaaaaa ttgaagatgt agttgttggt
    26641 actagtatac cttacaatta tgagaagtct aaattttaaa gtatcaataa cataatacta
    26701 tattgctaaa ctctacttaa ataaaaaaag agtgcattta ataattataa aaattatttt
    26761 tta
//
LOCUS       DACTZW010000057        25890 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.057, whole genome shotgun sequence.
ACCESSION   DACTZW010000057 DACTZW010000000
VERSION     DACTZW010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25890
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.057"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            247..948
                     /locus_tag="JAM15_12415"
     CDS             247..948
                     /locus_tag="JAM15_12415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HAT6799056.1"
                     /translation="MKFQEMINSPGLWIVSSFLVIISVVQAIVFMKSALKEASNLGIE
                     RKGIKAAIRSASVTAIGPSLSPVITLLSLVAVIGAPTTWMRLCDVGAARTELGVISLT
                     SNLSGVEVGSAAFGAEAFSYALWGMALNNLGWLLVVFILGHRMRGIVEKMNVKYNPTW
                     VKKLLAGATVGLFAYLLSNQIKTFEIPKLTPAVISAIVMLVLTTLFKKNQRLQELSLG
                     IAMLIGMFGTQIVLS"
     gene            974..1630
                     /locus_tag="JAM15_12420"
     CDS             974..1630
                     /locus_tag="JAM15_12420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799057.1"
                     /translation="MYDKKMIKIGRISIGLAIIANFIPAIYVGLRFGQMPMLSVIFQI
                     WGLVATTYGVSWIVQPIAYYPTLGAPGSYIGWLAGSVGDIRMPAASMAQKIAGVEAGT
                     HEGEVVGTIGTCCSIFVSASMITIFTIVGYKVIPLLPEFITDSFNYILPALFGAIYVD
                     IARKDIRAGGCTIAVALAIMYFGEKIGIPGGLLTLFIVLGGILITRVFFVIDSNKTKE
                     "
     gene            1786..3426
                     /locus_tag="JAM15_12425"
     CDS             1786..3426
                     /locus_tag="JAM15_12425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacylase"
                     /protein_id="HAT6799058.1"
                     /translation="MFDVKIANGIIIDGTGNSRYKGDVGIVGDKIMAIGDLSQKEAKE
                     TIDATGKFVSPGFIDFHTHSDLSLVYDKYTRSRIHTGVTTDVIANCGIGVAPIREEKK
                     QELIDYLGTRIIGTIPIKLNLHWNTMQEYFDYLTENSPAVNVVAYVAQGPVRINEMGF
                     SKEPATLEQLKNMKLEVRKAMEAGCVALSSGLVYLPGAYTKKEEMAELCKELIPYNGY
                     YISHIRDEGDEEMEALDEAIYIAKTAGVPLHISHLKVMGHKNFGTIDKVFKKLDEAEA
                     DGLEVTFDCYPYTAGMTSLGALLPPWAFEGGVENMVKRLEVQENRDRIIKELEEGIPG
                     WQCFYQLAGGWDGVVLASVMTEANKYVEGKTLMEVAKINGENPFDTFFRLLIEEKSKI
                     QVVVHTQGQEDTDKVVCHPKSCIGSDSMDLSTEGLLSLGKPHPRAFGTFGRIFSYYVR
                     EKGMLTFEEAVKKITYLSAKRLGIYKERGLLKENYFADIVVFDPDTIEDKATYSNPKQ
                     YTVGVEYVLVNGKIALAGGKQTDVCAGRVIKNPLSIAK"
     gene            3785..5107
                     /locus_tag="JAM15_12430"
                     /pseudo
     CDS             3785..5107
                     /locus_tag="JAM15_12430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426892.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            5304..6311
                     /locus_tag="JAM15_12435"
     CDS             5304..6311
                     /locus_tag="JAM15_12435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HAT6799059.1"
                     /translation="MGKYQDSKKVVRNYFEALENATGDEIENVLKQHMKSDYNWKGVY
                     PFREQEGTENVADVFWKPLKKSLSNMQRRQDIFIAGTNEIDNSEWVMSMGHFMGLFDK
                     DWLGIKHTRKMISLRYAEFNCVQDGKIAKTGLFVDIIGFMIQAGVNPLPPQTGSYFVY
                     PGPIDHNGLLFEDADEVEGVKTLALVNKMVDDLSELNESAAMGCPPEILEKSWAKDMI
                     WYGPGGIGASYTIPRYQEQHQLPFRNNLKGKTFNGHVCRFAEGNFACFFGWPNLTNVP
                     CGGFLGLPGGEVKADMQVVDVYYRKGDKLQENWVLIDIPYWLKQQGLDILERTKSIFN
                     A"
     gene            6349..7761
                     /locus_tag="JAM15_12440"
     CDS             6349..7761
                     /locus_tag="JAM15_12440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ester cyclase"
                     /protein_id="HAT6799060.1"
                     /translation="MASTNKNNVTSKEEEKEVSTSGPESCTVKENKAKMNQTNFSNIN
                     ENQTNENKTNTYKGNIDKGNIDKTNTNKSDINKVNIDTVDTDKLNTNTLTEKNKKVIF
                     KGEDNMSSTKIYYGDSLEVTPVGVMDYNDFSKQTKREQEIPGFDSKYRDFVDYIMKIT
                     HNIWEEKGIGVIYDTYHNNVTMHCGSSNLVGIKDVISNTLQTLHAFPDRRLIGQNVIW
                     SNFGADGFLSSHRVLSTATNLGDSNFGPATGRKINFRTVIDCATTNNRIHEEWLVRDN
                     LWIVTQLGLNPQEVAKSMAKASESKVLSLQSTYGICESMDGQFMPTKYQAKDDSVGEM
                     MLEMTSRIYNYKYINEVKKYYHDNAVVHFICDKDLNGYDEIQGMIVSLLSSIPNGSYE
                     VERVTCNQREKNEGYDVSIRWRLRGINEGIGFFGQPSGKHIEVMGINHYHILQGKVKE
                     EWITFDGMDVLKQMYMGVEE"
     gene            7906..9171
                     /locus_tag="JAM15_12445"
     CDS             7906..9171
                     /locus_tag="JAM15_12445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAT6799061.1"
                     /translation="MKTTVEIENDIILGKDYSNLKRGIAFFSIALIYFFYCYNFMVGT
                     FIKPTMIYALADGGFGFSLKQTEEIFAVMSFGTIPGTFIFGVISTKIGKKRTLISVAL
                     LIGLTTFIPMLSPTDIMLWKIARLCTGVVLGGVFGTAMPLVADMFPSKYRGKLAAILT
                     ALFSLAMIFGGKVYGVLGDANWQILMYTAIIPPIVGAILAIFFVPDDLEYTKELVKKG
                     KETGEKISYISMYKGKYLWIGLGTILLSGANFTAYSAFSNNATTYLVTGIGMSAAVAG
                     SIYSLQGIGQLVGYLFWGSIADKFGRKIPFIGMALAAVFVFIYTKLGGDNTTTFYMIS
                     VLLGVAVGYSGAWGAYYTELFPSKYRSLSSGMSFNGGRIISTFAIPAIAGTASGTLGM
                     MTIFYISIAVFVAGAIVWLFLPETLNNKK"
     gene            9213..10811
                     /locus_tag="JAM15_12450"
     CDS             9213..10811
                     /locus_tag="JAM15_12450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432878.1"
                     /note="Members of the Solute:Sodium Symporter (SSS), TC
                     2.A.21 as described in tcdb.org, catalyze solute:Na+
                     symport. Known solutes for members of the family include
                     sugars, amino acids, nucleosides, inositols, vitamins,
                     urea or anions, depending on the system; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/solute symporter"
                     /protein_id="HAT6799062.1"
                     /translation="MISSIDVCIIIGYLLLMLVIGYYSGKDNKNQEDYFLAGRSMPWI
                     PIALSVAATMISANGFIGGPGWAYVDGMYPVMVNITVPLAIFFALSITTPVIYKLKIT
                     SIYEYMGLRLGNYSRGLTIIQFFINSLIQASSMVYIPVLIIQMITGWSLYALVPIVVL
                     VSIIYTLLGGIKAVIWTDSIQMIVVISAVFIVIIVALKGMNLSFFDTLQIAQQSGKLN
                     TFDFSRDISVTNTFWATLIGGTVMWIRYFCFDQSQVQRVLTSKSLKCAKNSFVVSAFV
                     MNLVYYFMLLVGVILFVFYGGRTFETSNEIMITFILNELPVGAIGIIIAGVFAAAMSS
                     IDSILNSMTTVFTKDIYEFYFKKDNKESSLKVTMIITVVIGVVMTGFIIMGFGGSIKS
                     ILDLVGNYISYFAGPATGAFVLAMFTYKANDKGVSIGFIVGLVLGFFISNKYNVSWLW
                     NPAIGATITLIFGYIFSVILKKNHKVDDIKKYTAFGMRNHLISQGMDKVDGVSIVPFS
                     LGKQELIVLAFFIIQYIILFLIQF"
     gene            10846..11868
                     /locus_tag="JAM15_12455"
     CDS             10846..11868
                     /locus_tag="JAM15_12455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HAT6799063.1"
                     /translation="MNQKKVHYNKSATSKDVARLAGVSQSSVSRAFGSANGKGVKPEV
                     RERIFRVANEIGYVPNLVARGMISGKTNVIGLIVGDSLGPFYNRIINLFVEKIQEIGK
                     QCLVFKVPRQQSIDSIISKVIQFQVEAVIITASAMNKVMAETCEENNIPVILFNRFIP
                     GIKISTVYVDPIEGGGMVAEYLLKKGHKNIGYIQFTRETSEEMEKKIGFYSKLRQSGI
                     HNLKEESANYDYDSGYEAGKRMLALSNPPTAIFCTSDLIAIGVMDAARFEYKLRVPED
                     LSVIGYDDIQMASWKSYNLTTIRQPLDLLIEKTINILKSLLNEENPESVVEMLKPELI
                     ERGSTL"
     gene            complement(12326..13729)
                     /gene="hflB"
                     /locus_tag="JAM15_12460"
     CDS             complement(12326..13729)
                     /gene="hflB"
                     /locus_tag="JAM15_12460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HAT6799064.1"
                     /translation="MKMLNNFFKKINNPAPVFAQTKMERDNQTDDSLSTKPKTTFRDV
                     AGLDEVKEELFEIVDFMKSPQKYQKMGAKIPKGVLFYGPPGTGKTLLASAVAGETNSS
                     FFNVTGSEFVEKYVGVGAKRVRTLFEKARKEAPSIIFIDEIDAVGAKRHLESNNEKDQ
                     TLNQLLVEMDGFNKDSNVLIIGATNRLDLLDEALLRPGRFDRHIHIGAPNYHTRFEIL
                     KVHTDDKPIDKSVNLELLAKKTHGFNGAHLSNIANEAAIFAVRDDSECITSEHFDKAL
                     ERVIAGLESKNSALVEKEKKIVAYHEAGHALVSDIVGICPIQKISIVPRGQALGYVLQ
                     LPDEDRYIYTKDELIGKIKILLAGKASEELIFNHKSTGAKDDLKKVTEIANQMVCEYG
                     MSNLGFMTIDGNDKTFLCDKVQKEANRIVEICYKETLEMLKDNLEDLHSVSKFLFEKE
                     TMTHEELKDLIGKEAVN"
     gene            14523..15032
                     /locus_tag="JAM15_12465"
     CDS             14523..15032
                     /locus_tag="JAM15_12465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HAT6799065.1"
                     /translation="MSKELAINEKIKDKEIRVLSPTGEQLGVMPTKEAQAMANSKNLD
                     LVQISPNANPPVCKIMDYGKFRYEQARKEKEAKKKQKTIVVKEVRLRPGIEQNDLNTK
                     ANNAIKFLKKGDKVKVELRFRGRELGHKDIGKEVMLKFLDIIKEFGEPTKAPAFEGNN
                     MVVIIDPKK"
     gene            15060..15254
                     /gene="rpmI"
                     /locus_tag="JAM15_12470"
     CDS             15060..15254
                     /gene="rpmI"
                     /locus_tag="JAM15_12470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005211352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HAT6799066.1"
                     /translation="MPKMKTHRGAAKRLKKTGTGKLKRAKAFKKHILTKKSAKTKMNL
                     RKSTLVSDGDAKRIAQLLPY"
     gene            15310..15666
                     /gene="rplT"
                     /locus_tag="JAM15_12475"
     CDS             15310..15666
                     /gene="rplT"
                     /locus_tag="JAM15_12475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HAT6799067.1"
                     /translation="MARVKKAMNARKKHKKILKLAKGFRGSRSKLYRPANTFVMKALK
                     NAYIGRKLKKRDFRKLWIQRINAAARMNGISYSRLMNGLKLSGIEVNRKMLSEMAIQD
                     PEGFAKLAEVAKAKLA"
     gene            15976..16521
                     /locus_tag="JAM15_12480"
     CDS             15976..16521
                     /locus_tag="JAM15_12480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799068.1"
                     /translation="MNEKLMDCFVNPIKCKLLLEVFSNNRTTAKQLGEKFQDISKATL
                     YRYLNKMLKDDIIKVVEENKIRGTVEKVYAMKLDIADDVNKIIDENSGEEYAQLFTQY
                     MMGFLREFYEYAERKEKDILKEGSGFSVCPVYASIDEIVEVSKKIASILEPLRNNPHE
                     EGRRMHSIGVIITPPKEDEGK"
     gene            16508..16681
                     /locus_tag="JAM15_12485"
     CDS             16508..16681
                     /locus_tag="JAM15_12485"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799069.1"
                     /translation="MKGNKSDLHEVEPIYTENRFMIYICIQSKVSLHGLYFIVPFHPM
                     TWSGTMKFFNFSY"
     gene            16957..18882
                     /locus_tag="JAM15_12490"
     CDS             16957..18882
                     /locus_tag="JAM15_12490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide phosphodiesterase"
                     /protein_id="HAT6799070.1"
                     /translation="MKIKFVIMPLVIFLIVLFVGCQSTKDTEVKAKDTEIKILGTGDL
                     HSILTDSMVSYVNEEREKNKNLLMVDAGDFYGTQSREMWEWSSGKKLINIKRNGRAEY
                     DDIIKSSKDEVPIVKDMAKLKYDAVVLGDNEFISNDKQSLDKLVSDFKNNNMPLVSAN
                     IYEQSGENYVQPYVMKNIKTDEGNVKVGILGLTIKEVGETLGLEDFEKDKKARELGEQ
                     ADYKGKLYANDLVEDAKKWIKVMEKESPDIIVAVVHSGEEPKTDRNLGNRIKELATTV
                     DGIDAIVAGHTHEKIDEHKYKNKSGDEVIVTQPGWHGDRVSEINFKLNKENGKWDIKE
                     KSSKLKIIDKEVSIVATADLHSHFSDKLTVDLVNERSNPIEPVVVDAGDFLDPQTDEM
                     TQWYKEWKSIRDNNSDKTISRCPMVMDMNQGMYDAVVLGNHEFVSEKDEFWSDERLLD
                     AVIEDFEQVAISVLSANIYRQSGKNYVKPYIIKDVETSEGNVKVGILGLTIKEVGKGL
                     KNVNLQEQFQYKDKLYANDLVEDAKKWVKVMKKKKPDIIVAVVHSGEEPKNPKHPGNR
                     IKELATTVDGIDAIVASHTHEKIDEHEYKNKSGEKVIVTQPGEHGKYYSKITFKVNKE
                     KGSWIINDKFSKTIEVE"
     gene            19283..21187
                     /locus_tag="JAM15_12495"
     CDS             19283..21187
                     /locus_tag="JAM15_12495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide phosphodiesterase"
                     /protein_id="HAT6799071.1"
                     /translation="MKIKFIIVASIIFLIVLLVGCQSTKDTEINVLATSDLHSIIPDN
                     LISYVEEERKYDENLLMVDAGDFFDMQSGEMNKWFTGQKLVRFKDGIPEYKKIAEPRE
                     GEVPLAKKMAKLKYDAVTFGNHEFVSNDKQSLDKLVSDFKNNNIPLVSANVYEQSGEN
                     YVKPYVMKNINTDKGTVKVGILGLTIKEVGERSRFKSFKQDKKARELGEQPQYKGKLY
                     ANDLVEDANKWVKVMEKKEKPDIIVAIVHSGEEPKNPKNPGNRIKELATTVEGIDAIV
                     AGHTHEKIEQHTYKNNSGEEVIVTQPGAHGNSISKINFKLDKKNDKWFIKDKYSELKV
                     FGKEVNIITTSGLNPKFSDEMAVNLFNERDRDVQPIFIDTGDFLNTNTKEMTKWAKEW
                     QYNENKGIYKKINEWPIVYLGYDAVVLGSHEFTEDKETFEEKKSTLDYIIENFEEMKI
                     PVLSANIYDESGENYVKPYIIHNVETREGNIKVGVLGLTTTDKDEEDLSRSSLSKDSK
                     TSKIPEETGKLYTNNLVKDASEWVKVMQKESPDVIVAVVHSDNNSTLKNPSSEVKKLA
                     MSVDGIDAIVVGHTKNKVEEHIYKNKSGDEVIVTQSGEDCYSKISLELRKENGKWNII
                     NKYSKAIKMK"
     gene            21693..22472
                     /locus_tag="JAM15_12500"
     CDS             21693..22472
                     /locus_tag="JAM15_12500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HAT6799072.1"
                     /translation="MNYKKIAIITGANSGFGKEFLKLLINEEEITEIWAVARNKARLN
                     QLVDEFGSKVKVFSKDLSKIEEVKEIGTFLSKENVCIKYLINNAGFAKFCSYNDLSID
                     ESINMIDLNISAVVALGLICIPYMQKGSHIMNISSQASFQPLPYQNIYSSTKAFIRNY
                     TRALNVELKSKGINAIAVCPGWMSTNLFKRGIVVAEKGTKNFPGIVSPDVVAKKALKD
                     AKKNKDISVYGINTKSSHLLAKLLPQKMMMKVWLMQQHIKE"
     gene            complement(22782..23603)
                     /locus_tag="JAM15_12505"
     CDS             complement(22782..23603)
                     /locus_tag="JAM15_12505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002572585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAT6799073.1"
                     /translation="MKLKIVGSGGMSIIPSSFCKCKICEEARQKGGRYERLGPSLYID
                     DIKMLIDTPEDIAVACNRQKISEVKHISISHHDPDHVKGIRIVEKIGCDFITGENNPI
                     GFYALPEVIEDINRTNLDCLKYYGDVINCISINETSHVKINNFDIDLINNNPDRNITF
                     YVIKENEKKVIYACCNPKPFTHSDMYFDADVLIISLVSDDGILNDGTKLKDTPFKDEI
                     FTLDEIVEIKNYYRIKKIIITHIDEMWGKSYGYYSELEKKLDNIYFAYDGMEIIV"
     gene            complement(24194..25012)
                     /locus_tag="JAM15_12510"
     CDS             complement(24194..25012)
                     /locus_tag="JAM15_12510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAT6799074.1"
                     /translation="MFKIGDFSKLSKISIRMLRHYDEIGLLTPSHTNKTNGYRYYSAD
                     QLSTTNRIHALKDMGFGLYSIKEILTEYNDKESLIKYLNIHHSQVKEQLEDTQKKLLK
                     IETTIKRIGGNDIMKNYDVTIKNFAPKYMMTLRRVIPTYQDEGMLWHQAFLETKDQNV
                     QIEPPKYSKAVFYDTGYKEDYVDVEVQVAVSGKYKDTEHVKFKTVPSVTAATAIVNGN
                     FNQVADACEAIGNWISDNNYDVDGPMFNIYHVSPGNDSNPDNWVTEVCFPVKKK"
     gene            25180..25761
                     /locus_tag="JAM15_12515"
     CDS             25180..25761
                     /locus_tag="JAM15_12515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAT6799075.1"
                     /translation="MKSNDKDARERIIEVTLNLLNEVDDIEEITVRKIAERANVGVGL
                     INYHFKTKDNLLSTAIGDVMSNIIAELYDDSVYTLRPIEDLKNLLKKLCDTGLHYEKV
                     LPFVLNQCITNGDMQAELDIVPMLRKIFGNKKDEMSLRIIALQIILPIQISALSTESF
                     QLYSGINIKNKYERDKFIDILIENIIGEDVDVR"
BASE COUNT         9698 a         2991 c         4638 g         8563 t
ORIGIN      
        1 taataaaata ccttataagt taattacagg ttaaaaaaat aatatgtgaa ttttctgata
       61 tttactaatt atcaataaag tatttaagta ttaatgtttt tagtgagact ttaagacaga
      121 taatctccta ttaaagatac tatatcttag ataaaataaa ttaaaacaat ataaaaacat
      181 aacaagatta cagaaagaaa gctcataata aaacactaaa aaatttattt taaggaggaa
      241 taaagtatga agtttcaaga aatgattaat agcccaggtc tttggattgt ttctagtttt
      301 ttagtaatta tttcagttgt tcaagcaatc gtatttatga aatcagcact taaagaggct
      361 tcaaatcttg gtattgaaag aaaaggaatt aaagcagcaa ttcgctcagc tagtgttaca
      421 gcaattggac cctctctatc tcctgttatt acattattat cactggtagc tgtgattggt
      481 gctcctacga cttggatgag gctttgtgat gtaggagctg ccagaacaga acttggagta
      541 atatctctta catcaaattt atctggagta gaagtaggta gtgctgcatt tggagcagaa
      601 gctttttcgt atgcactatg gggaatggct ttaaataact taggttggtt gcttgttgta
      661 tttattttgg gtcatagaat gcgtggaatt gttgaaaaaa tgaatgtgaa atataatcct
      721 acttgggtta aaaaactact tgcaggggct acagttggat tatttgctta ccttctttca
      781 aatcaaataa aaacattcga aataccaaaa cttacaccag cagttatttc agctatagtt
      841 atgctagtat tgacgacttt atttaaaaag aatcaacgat tacaagaatt atccttaggt
      901 attgccatgt tgattggtat gtttggcaca cagattgtac tatcatgatt aaaacagata
      961 agaggtgata attatgtatg ataaaaagat gataaaaata gggcgaattt ctataggtct
     1021 tgcaattatt gcaaatttta ttcctgcaat ctatgtaggt cttcgctttg gtcagatgcc
     1081 aatgctttct gttatattcc aaatttgggg attagttgct acaacttatg gagtgagttg
     1141 gattgttcaa cctatagctt attatccaac actaggagct ccaggttctt atataggttg
     1201 gcttgcaggt tctgttggag atatacgtat gcctgcagca tcaatggcac agaaaattgc
     1261 aggtgtagaa gcaggaactc atgagggtga agttgtagga acaattggta catgttgttc
     1321 aatctttgta tcagcttcta tgattactat ttttaccatt gtaggctata aagtaattcc
     1381 tttgttacct gaatttatta ctgattcatt taattatata cttccagcat tgtttggggc
     1441 aatttacgtt gatattgcgc gtaaagatat tcgagctggt ggatgtacga ttgctgtagc
     1501 attagctatt atgtactttg gtgaaaaaat tggtatacca ggtggattgt tgacattgtt
     1561 tattgtgtta ggtgggatac ttattacaag ggttttcttt gtaattgata gcaataaaac
     1621 gaaagaatag gattgtttac taggaagaaa gactagaatt atttgctgag aaaaagaata
     1681 ggattgttta ctaggaggaa agactagaat tatttgttga gaaaaaagaa taggattgtt
     1741 tattaagaaa tatgaatata aataagtctt gaaaggagaa gaagaatgtt tgatgttaaa
     1801 attgccaatg gaataatcat tgatggtaca ggaaattcaa gatataaagg tgatgtaggg
     1861 attgtaggag acaaaatcat ggctattgga gatctaagtc aaaaagaggc taaagagact
     1921 atagacgcaa ctggaaaatt tgtatcacct ggttttatag atttccacac tcattctgat
     1981 ttatctcttg tgtatgacaa atacacaaga agccgtatcc atacaggtgt aacaacagac
     2041 gttattgcaa actgtggtat aggagttgct ccgataagag aagagaagaa gcaggagtta
     2101 attgactatc ttggaacgag gataattggt acaattccaa taaaattgaa ccttcactgg
     2161 aatacaatgc aggaatactt tgattactta actgaaaatt ctccagcagt aaatgttgta
     2221 gcttatgtag cacaaggacc tgtacgtatc aatgaaatgg gattttcaaa ggagccagct
     2281 actttagaac aacttaaaaa tatgaagttg gaagttagaa aagctatgga agctggatgt
     2341 gtagctcttt cgtcaggatt agtttattta ccaggagcat atacaaagaa agaagaaatg
     2401 gctgaattat gtaaggaatt gataccatac aatggatact atatatctca tattagagat
     2461 gagggtgatg aagaaatgga agctcttgat gaagcaattt atatagctaa gacggcagga
     2521 gttcctctac atatttctca tttaaaagtc atgggtcata agaattttgg aactattgat
     2581 aaggtattta aaaagctaga tgaagctgag gcagatggct tggaagttac ttttgattgt
     2641 tacccatata cagctggaat gacatctttg ggtgcacttt tacctccttg ggcttttgaa
     2701 ggtggtgtag aaaacatggt aaaacgatta gaagtgcaag aaaataggga cagaattata
     2761 aaagaactag aggaagggat tcctggatgg caatgtttct accagttagc aggtggttgg
     2821 gacggtgttg tactagcctc tgtaatgact gaagcaaata aatatgtaga gggtaaaact
     2881 ttaatggagg tagctaaaat caatggtgaa aatccatttg atacgttctt taggcttttg
     2941 attgaagaaa aaagtaaaat tcaagtagtt gttcatacac aaggtcaaga ggatacagat
     3001 aaggtcgttt gccatccaaa gtcatgtata ggttctgata gtatggacct ttctacagaa
     3061 ggtttacttt ctcttggaaa gcctcatccc cgtgcatttg gtacttttgg acgaattttc
     3121 tcttactatg ttagagaaaa agggatgttg acttttgagg aagcagttaa aaagataact
     3181 tatctttcag caaaacgctt aggaatttat aaagaaaggg gtctacttaa ggaaaattat
     3241 tttgctgaca ttgtggtatt tgacccagat acaatagaag ataaagcgac ttatagtaat
     3301 cctaaacagt atacagtggg agtggaatat gtattggtaa atggtaaaat tgcattggca
     3361 ggaggaaagc aaactgatgt atgtgctgga cgtgtaatta aaaatcctct tagcatagca
     3421 aaatagaata cattaagaac ttttataaaa atagtctttc tttgaatatt aaggaaggct
     3481 atttttgtta aattaataaa gattactcta cttgtgtttt ctagagaatt taactttaag
     3541 tagaaaaaac aatatattaa ttgtaaaatg taattaatat taatggataa gatttaaata
     3601 caaaaactta aatacaaaaa tgttttaaca gatagtcata attaaaaaac ttaaagtaac
     3661 tttttatata agatataatt gattatgcaa aattttatga agcagcaacc ttgttacttt
     3721 aagtcaaggg aggttcagaa agtgtcttaa gagataatag tatctttagg aaaggagaaa
     3781 cgaaatgaaa atactttatg taggaccagg catggtaatc gacaaaatac tagcagtaag
     3841 taaaaagaat tttcccaata ttgaagcaga ttttcttaga tatgatagat atattgaagt
     3901 acctgattta ttggaaaaat atagaggtag agtagatgca gttcttttta caggtaaatc
     3961 gccatttaaa ttttttgaaa aaagacaaaa agattttgtg ttgtctgatt atattcctag
     4021 acatgaaaca acattataca gagtattgct tgaaattaca tatttgctta aattcgatat
     4081 tagtagactt agtatagata cttatgataa agctatgctg aagagattgt ataaagaaat
     4141 tggagttgaa tttaaggatg aacatatgtt ttttgcagag caaaagtatt tagaagagga
     4201 ctacataaag tttgtgcttg aatttcataa atataattat taaaataatg acatatgttg
     4261 ttgtattaca ggtcttgaag aagcatatca tgcaatgaaa aaagagaata ttccagtagt
     4321 tttagccttg ccttctgagg atgtaatggt acaaagtata aaaaacattc agatgcgtta
     4381 tattgcaaag aaaaacaatg agaatcagat tgttgttctt gctatcaaac ttaatatgcc
     4441 ttcagaatat tcactgatga aggaagatga gtacgcttat ctttcacaaa ggattaagat
     4501 tcttgataaa ctataccatt tcaatagccg tatagatggt gttttggtag agcagagtag
     4561 aagcgaattt atgattttta caactaaaaa aatacttgag ttagaaacaa agaagtacag
     4621 agatatttat ttgttggata tgattcgtga agtttcagtt ataaacactt atataggaat
     4681 tggctatgga aaaacagcaa atgaagctaa atttaacgct tatgagagta ttaagatggc
     4741 tcaaagtcaa aaaaatgatg cagcatatgt agtttttgaa aatggagaaa ttatgggacc
     4801 actaaagcca aatcctgctg tcaaagagaa aaatagcttt gatgaacgat tttatcaaat
     4861 tgctacagag acagggctaa gtgctaatac tgtatataaa gtgttcaata aaataataaa
     4921 tagtggaaaa actgaattta catcaaagga attagctatt atatgtggtg taagtattag
     4981 aactatggac aggattatac ttagattgtg tgattctggt tattgtgagg tagtgagtga
     5041 acagcttatg agcaagtatg gtagacccag tagaatatta cgttttaaac cttttctgtt
     5101 gttttaaata gatataagtc aaaaattaaa tttttatgat aacattttct ttacaatttt
     5161 ttagatatat gttaatattt agaaaaatgc atatgtattc ataaaataaa ctcaaaacag
     5221 ctaaaaaatc attaaaaaag aaatcgtatg cataaaatga gaaagttaat ttataactta
     5281 aataaatctg ggaggagata attatgggaa aatatcagga ttcaaaaaaa gttgtaagaa
     5341 attattttga agcattagaa aatgctactg gggatgagat tgaaaatgtc ttaaagcaac
     5401 atatgaaatc agattataac tggaaaggtg tgtatccatt tcgtgaacaa gaaggcactg
     5461 aaaatgtagc agatgtattt tggaagcctt taaaaaaatc attgagtaat atgcaaagac
     5521 gacaagatat tttcattgca ggaacaaatg agattgacaa tagtgaatgg gtaatgagta
     5581 tggggcattt tatgggactt tttgataagg attggcttgg cattaaacat actcgtaaaa
     5641 tgattagttt aagatatgca gaatttaact gtgttcaaga tggtaaaatt gctaaaactg
     5701 gattatttgt agatataatt gggtttatga ttcaagcagg agttaatcca ttgccaccac
     5761 aaacaggttc atattttgta tatccagggc caattgatca taatggatta ctttttgaag
     5821 atgcagatga agttgaagga gtaaaaactt tagcattagt aaataaaatg gtagatgatt
     5881 tatctgaatt aaatgaaagt gctgctatgg gatgcccacc agaaatactt gaaaaatctt
     5941 gggctaaaga tatgatttgg tatggtccag gtggaattgg tgcttcttat actataccta
     6001 gatatcaaga gcaacaccag ctaccattta gaaataattt aaaaggaaag actttcaatg
     6061 ggcatgtatg tagatttgca gaaggtaatt ttgcttgttt ctttggatgg cctaatctga
     6121 ctaatgtacc atgtggaggt tttttaggat taccaggtgg agaggttaaa gcagatatgc
     6181 aagttgttga tgtttattat cgtaagggcg ataaacttca agaaaactgg gtgttaattg
     6241 atattcctta ttggttgaaa caacaagggc ttgatattct tgagagaact aaaagtattt
     6301 ttaatgctta gttatgcata cgtattctaa aacaaagggg gatataaagt ggcatctacc
     6361 aacaaaaata atgtaacaag taaagaggaa gaaaaagaag tttctacaag tgggcctgaa
     6421 tcatgtacgg ttaaagaaaa caaagctaaa atgaatcaaa ctaattttag taatataaat
     6481 gaaaatcaaa caaatgagaa taaaacgaac acatataaag gaaatataga taaagggaat
     6541 atagataaaa caaacacaaa taaatccgac ataaataaag ttaacataga tacagtggat
     6601 acagataaat taaatacaaa tactcttact gaaaaaaata aaaaagttat atttaagggg
     6661 gaagataata tgtcatctac aaaaatttac tatggagatt cattagaagt aacgcctgtt
     6721 ggagtaatgg attacaatga tttttcaaag cagacaaaaa gggaacagga aatacctgga
     6781 tttgattcta agtatagaga ttttgtagat tatattatga agattacaca taatatctgg
     6841 gaagaaaaag gtataggtgt tatttatgat acatatcaca ataatgttac aatgcattgt
     6901 ggctcttcaa atttagttgg tattaaagat gttatttcca atactcttca aacattacat
     6961 gcgtttcctg atagaagatt aattggtcaa aatgtaatat ggtctaactt tggtgctgat
     7021 ggttttttat cttctcaccg tgttttgtct acagcaacta acttaggtga tagtaatttt
     7081 ggaccagcaa caggtagaaa aataaacttt agaactgtaa ttgattgtgc cacaactaac
     7141 aatagaatcc acgaagaatg gttggttaga gataatttat ggattgttac tcaattagga
     7201 ttaaaccctc aggaagtagc aaagagcatg gcaaaggcaa gtgaatctaa agtgcttagc
     7261 ttacaatcaa cttatggtat ctgtgaatct atggatggtc aatttatgcc aactaagtat
     7321 caagcaaaag atgattctgt tggcgaaatg atgcttgaaa tgacaagccg tatttataat
     7381 tataaatata taaatgaagt taaaaaatac tatcatgata atgcagtagt acattttata
     7441 tgtgataaag atttaaatgg ttatgatgag attcaaggaa tgattgtaag tttactttcg
     7501 tcaattccaa atggaagtta tgaagtggaa agagtaactt gtaatcaaag agaaaaaaat
     7561 gaaggttatg atgtatctat aagatggaga ttacgtggaa taaatgaagg tataggattt
     7621 tttggacagc cttctggaaa gcatatagaa gtaatgggaa tcaatcatta tcatatactt
     7681 caaggtaaag taaaggaaga gtggataact tttgatggta tggatgtatt aaaacaaatg
     7741 tatatgggag tagaagaata aagctgttta gagtataaat aattttgaaa tgtatatagg
     7801 gaagtattgc tttataaaat ttaagtgggg aatgtatatg aaaaatagat gtttaaactt
     7861 ttagcaaaaa ttatgactaa atttaaaagg gggaattata aaaatatgaa aacaacggtt
     7921 gaaatagaaa atgatatcat attaggaaaa gactattcaa acctaaaaag aggaattgca
     7981 tttttttcaa ttgctttaat atactttttt tattgctaca attttatggt gggtactttt
     8041 attaaaccaa caatgattta tgctttagca gatgggggat ttggcttttc attaaaacaa
     8101 acagaagaaa tatttgcagt tatgtctttt ggtacaattc caggtacatt tatttttggg
     8161 gtgatttcta caaaaattgg gaagaagagg actttaatta gcgttgcttt actgattgga
     8221 ttgacaacat ttataccaat gttatctcct acagatatta tgttatggaa aatagcacgt
     8281 ttgtgtacag gagtagtgtt gggaggcgta tttggaacag ctatgccttt agttgcagat
     8341 atgtttccaa gtaaatatcg tggtaagtta gctgctatat taactgcttt attttcatta
     8401 gcaatgattt ttggtgggaa agtatatggc gttttaggtg atgcaaattg gcaaatattg
     8461 atgtatactg cgattatacc acctatagtt ggagctatct tagcaatctt ctttgtgcca
     8521 gatgatttgg agtatacaaa ggaattagtt aaaaagggaa aagaaactgg tgaaaagatt
     8581 agctatataa gtatgtataa gggaaaatac ttatggattg gattgggaac gattctttta
     8641 tcaggtgcaa attttacagc atattcagca ttttcaaata atgcaactac atacctagtg
     8701 acaggaatag gaatgtcagc agcagtggct gggtctatat atagtttaca aggaattggt
     8761 caattagtag gatatttatt ctggggttca attgcagata aatttggaag aaaaatacct
     8821 tttataggta tggcattagc agcagtattt gtttttatat atacaaaatt aggtggagat
     8881 aatacaacaa cattctatat gatatcagta ttactaggtg ttgctgttgg atattctgga
     8941 gcatggggag catactacac agagttgttt ccaagtaaat atcgttcgtt gtcatctggt
     9001 atgtcattta atggaggaag gattatatct acgtttgcaa tacctgctat agctggtaca
     9061 gcttctggta ctttaggtat gatgactatc ttttacatat caatcgcagt ctttgtagca
     9121 ggtgctattg tatggttatt cttaccagag acgttaaata ataaaaaata aaatactagg
     9181 aatttatttt gttacttaga aaggggtggc ttatgatttc atcaattgat gtatgtatta
     9241 taataggata tttgctatta atgttagtta ttggttatta ttcaggaaaa gataataaaa
     9301 atcaagaaga ttatttcttg gcaggtaggt caatgccatg gattccaatt gctttatcag
     9361 ttgcagctac tatgattagt gcaaatggct ttataggtgg tcctggatgg gcatatgtag
     9421 atggaatgta tccagtaatg gttaatatta cagtaccttt agcgatattt tttgcactga
     9481 gcattaccac cccagttatc tataaattaa aaataacctc tatatatgaa tatatgggac
     9541 ttcgtttagg aaattattca agaggattaa ctattattca attttttatt aattcattga
     9601 ttcaagctag ttctatggta tatattccag tgcttattat tcaaatgatt actggctggt
     9661 cactttatgc tttagtccca atagttgtac ttgtatcaat tatatatact ctattaggtg
     9721 ggattaaggc agttatatgg actgatagta ttcaaatgat agtagtaata agtgctgtat
     9781 ttatagtaat tattgtagcc ttaaaaggaa tgaatctaag tttctttgat acattacaaa
     9841 ttgcacaaca gagtggaaaa ttaaatacat ttgatttcag tagggatatt tcagtgacaa
     9901 atactttttg ggctacttta attggtggaa ctgtaatgtg gataagatac ttttgttttg
     9961 accaatctca agtacaaaga gttttaacat ctaaatcttt aaaatgtgca aaaaattctt
    10021 ttgtagttag tgcatttgtt atgaatttag tttactactt tatgctattg gtaggagtaa
    10081 ttttatttgt tttttatggg ggaaggacat ttgaaacttc aaatgaaata atgattactt
    10141 ttattttaaa tgaacttcca gtaggagcca ttggaattat tattgcaggt gtgtttgcag
    10201 cagcaatgtc tagtatcgac tctatattaa acagtatgac aactgttttt acgaaggata
    10261 tttatgagtt ttatttcaaa aaagacaaca aagaatcatc attaaaagtt acaatgatta
    10321 taactgtagt tataggagtt gttatgacag gttttattat tatgggattt ggaggaagca
    10381 tcaaatcaat tcttgacctt gttggtaact acatctcata ctttgctgga ccagctacag
    10441 gtgcatttgt actagcaatg tttacatata aagctaatga taaaggagta tctattggtt
    10501 ttattgtagg gttagtttta ggatttttta tttctaataa atataatgtg agttggttgt
    10561 ggaatccagc aataggtgct acaataacat tgatatttgg atatattttt agtgtcattt
    10621 taaagaaaaa tcataaagta gatgatatta aaaaatacac tgcatttggt atgagaaatc
    10681 accttatttc tcaaggaatg gataaagtag atggagtatc tatagtgcca ttttctttag
    10741 gtaaacaaga actaattgta ttagcttttt ttattatcca atatattata ttatttttga
    10801 tacaatttta agaagaaata ctagatattt aaggagaaat actaaatgaa tcaaaagaaa
    10861 gttcattata ataaatcggc tacatcaaaa gatgtcgcaa gattggcagg agtatctcaa
    10921 tcatctgttt caagagcatt tggtagtgca aatggaaagg gcgtaaaacc tgaagtaaga
    10981 gaaagaattt ttcgtgtagc aaatgaaata ggatatgttc ccaacttggt tgcacgtgga
    11041 atgattagtg gaaaaactaa tgttatagga ttgatagttg gtgatagtct aggtccattt
    11101 tacaatagaa ttatcaattt atttgtagaa aaaattcaag agataggtaa acagtgtctc
    11161 gtttttaaag ttcctagaca acaaagtata gatagtataa tttcaaaagt aattcagttt
    11221 caagtagaag ctgtgattat tacagcttcg gccatgaata aggtgatggc tgagacttgt
    11281 gaagaaaaca atattcctgt gattcttttt aatcgtttta tacctggtat aaaaataagt
    11341 acagtctatg tagacccaat tgaaggtggg ggcatggttg ctgaatatct gcttaagaaa
    11401 ggtcataaga atataggata tattcaattt acgagagaaa caagtgaaga aatggaaaag
    11461 aaaattggat tttattctaa gttaagacaa agtgggattc ataaccttaa agaagaatct
    11521 gcaaactatg attatgattc tggatatgaa gcaggtaaga gaatgttagc attatcaaat
    11581 cctccaacag caattttttg cacaagtgac ttgatagcta ttggtgtaat ggatgctgca
    11641 aggtttgagt acaagttgag agtgccagag gatttatcag tgataggata tgatgatatt
    11701 caaatggctt catggaagag ttataattta acgacgatta gacaaccact agatttgttg
    11761 attgaaaaaa caattaacat acttaagtcc ttattaaatg aagaaaatcc agagtcagtc
    11821 gttgaaatgt taaaacctga attgattgaa agaggttcta cactttaagt gatagatatt
    11881 taattaagtg atagatattt aattaagtgg tagatattta attaagttgt agatatttaa
    11941 tcaagtgata gatacctaat taagttgtag atatctgata agaaattttt aagttttcaa
    12001 tcgttctaaa ttgtgagtat aaaaatctac taaatttagt tatgtaaaat ataaattata
    12061 agtgtagaaa ctaggctact agcttttata ccacttcaaa cattactgga agtagttaag
    12121 tttacagcag tttagtttta tgtagatata atattctgta aatagacaaa attaaaatat
    12181 gtaattaaaa tatgtaagtg tctcaaaatg aaatttttaa tttatgaggc acttttttgt
    12241 ataaaatcaa atatattttt ataactttaa caataaaaag aggcttatct ctattttgag
    12301 acagcctcaa atttttaaaa ctatattagt ttacagcttc ttttcctatc aaatctttta
    12361 actcttcatg agtcatagtt tctttttcaa ataagaattt agaaacagaa tgtaaatctt
    12421 caagattatc ctttaacatc tctaaagtct ctttataaca aatttcaact atacgatttg
    12481 cttccttttg aaccttatca cataagaaag tcttatcatt tccatcaata gtcataaatc
    12541 ctaagttact cataccatat tcacaaacca tttggttagc tatttcagtg actttcttta
    12601 agtcgtcctt tgcaccagta gatttatgat taaatattaa ttcttctgaa gcctttccag
    12661 caagtaatat ttttattttt ccaatcaact catccttagt ataaatatat ctatcttcat
    12721 caggtaattg aagaacataa cctaatgctt gtcctctagg aactatagat attttttgta
    12781 taggacaaat tcctactata tcacttacaa gagcatgtcc agcttcatga tatgctacta
    12841 tttttttctc tttttcaacc aatgcagagt ttttagattc tagccctgca ataactcttt
    12901 caagtgcctt gtcaaaatgt tctgatgtaa tacactcgct gtcatctcta actgcaaata
    12961 tagctgcttc atttgctata tttgaaagat gagccccatt gaaaccatga gtttttttag
    13021 ctaaaagttc tagatttaca gatttgtcta taggtttgtc atctgtatgt acctttagaa
    13081 tttcaaatct agtgtgatag tttggtgcac ctatatgaat gtgtctgtca aatcttcctg
    13141 gtctaagtaa agcttcatct aataagtcaa gtctattggt agcacctatt attaatacat
    13201 tggaatcttt attaaatcca tccatttcaa ctaaaagttg gtttagtgtt tggtcttttt
    13261 cgttgttact ttcaagatgt ctctttgctc ctacagcatc tatttcgtct ataaatatta
    13321 tacttggagc ttcttttcta gctttttcaa atagagttct aactcttttt gctcccacac
    13381 ctacatattt ttcaacgaac tctgaaccag taacattgaa aaatgatgag tttgtttcac
    13441 cagctacagc agatgcaagt agggttttac ctgttcctgg aggaccataa aataatactc
    13501 ctttaggtat ttttgcaccc attttttgat atttttgtgg tgacttcata aaatcgacta
    13561 tttcaaatag ttcttctttt acttcgtcta atccagcaac gtctctaaat gtagtctttg
    13621 gttttgtaga aagtgaatca tctgtttgat tatctctttc catttttgtc tgtgcaaaga
    13681 caggagctgg attgttgatt ttcttaaaaa agttgtttag cattttcata ttcacacctc
    13741 aggtaattaa ttattgttaa tcaattttat attttccata tttactattt tttattattt
    13801 atttttcatg gaaaaaatat acatgttatc taaataaaaa taaatttgta agatgtatga
    13861 aaaaatgaat ttatgtatat agagatttct acttatgtat tgaataaagt attacaaatt
    13921 ataaattatg tattgattat atattgagta aagtattata aagcatgtat tgattaagta
    13981 tttattaagt attgaataaa atattacaaa tttagttgaa atgaaaatga taaaaaatgt
    14041 tgtgctatat tttacaaatc atataaatag agaaattgtt gtagcacaaa gtaataggta
    14101 gtatattaga atataatata ggatttgttg tgtagtatag tagcatatta gaatataata
    14161 taggatttgt tatgtagaat atatagagtc atgtagaata taaatatata aaaggatttt
    14221 gggtataaat ttaaaaatta atagcaaaat gagtagtata gacatataat tagtagtagg
    14281 aagtaattaa atttttccta aacaaaaaaa atagttgcaa ataatttgat taagtgatat
    14341 agtaaataag gtaagaataa aacaaagaag aagtccgctt ctcaccttac gccggaggtt
    14401 agtaaggtaa atataagtta aagcttaatt ttaatttaag tttgtttaaa tttggtaact
    14461 tatattgcgg atgattacgt catccgcttt ttattttata aaaattttgg aggtgtccta
    14521 caattagcaa agaattagca atcaatgaaa aaataaaaga taaggaaata agagtccttt
    14581 caccaacagg tgaacaactt ggagtaatgc ctactaaaga agctcaagca atggctaata
    14641 gcaaaaactt agatttggtt caaatctcgc cgaatgcaaa tccaccagta tgtaagataa
    14701 tggattatgg aaagtttaga tatgagcaag cgagaaaaga gaaagaagct aagaaaaaac
    14761 aaaaaactat agttgtaaaa gaagtaagac ttagaccagg tattgaacaa aatgatttaa
    14821 atacgaaagc taataatgct ataaagttcc ttaaaaaagg ggataaagtc aaagttgaac
    14881 ttagatttag aggaagagaa ttaggacata aagacatagg taaagaagtt atgcttaagt
    14941 ttttagatat aataaaagag tttggagaac caacaaaagc ccctgcattt gagggtaata
    15001 atatggttgt aattatagat ccaaaaaaat agatgattaa ctgagaggag gaatttgtca
    15061 tgcctaaaat gaaaactcat agaggtgcag caaagagatt aaagaaaaca ggaactggaa
    15121 agttaaagag agctaaagct tttaaaaaac atatattaac taaaaaatct gcaaaaacta
    15181 aaatgaactt aagaaaatca actttagtaa gtgatggaga tgccaagaga atagcacaat
    15241 tattaccata ctaagataca gattataaat aataactata gaagagggat ataaaaggag
    15301 gtcataacga tggcaagagt taaaaaagct atgaacgctc gtaaaaagca taagaaaata
    15361 ttaaaacttg caaaaggatt cagaggatct agaagcaaat tatatagacc agcaaataca
    15421 ttcgtaatga aagcattaaa aaatgcttat ataggaagaa agttaaagaa aagagacttc
    15481 agaaaacttt ggatacaaag aataaatgca gctgctagaa tgaatggaat atcttattca
    15541 agattaatga atggattaaa attatctggt attgaagtta acagaaaaat gttatctgaa
    15601 atggctatac aagacccaga aggatttgca aaattagcag aagttgctaa agcaaaatta
    15661 gcttagtatt gaatcatgag atgtaaagtc tttgagttat ataaataatt caaggacttt
    15721 tttatttttt gaaaaatact tattagtgtc atgtacaacc aattttataa tgataaataa
    15781 aataagcaat acaatagaat tttatgagat ttattataag aattgttaca attatttatc
    15841 atagctataa aaagtcatag taaaaatgat attgatgtat gtttatatat gtataaatct
    15901 ttcaatcaat cttgaattaa tattatcaac atgataatat tatcttatta ataatataaa
    15961 taagggggag ataatatgaa tgagaaacta atggattgtt ttgtaaaccc aattaaatgc
    16021 aagttattgc ttgaagtttt ttcaaataat cgaactacag ctaaacaatt aggagaaaaa
    16081 tttcaagata tatcaaaggc aacactttat cgttacctta ataaaatgtt gaaagatgat
    16141 attataaaag tggttgaaga aaataaaata aggggaactg ttgaaaaagt atatgctatg
    16201 aagttagata tagctgatga tgtgaacaaa attatagatg agaactctgg agaagaatat
    16261 gctcaactgt ttactcaata tatgatggga tttttaagag aattttatga atacgctgaa
    16321 agaaaggaaa aggatatcct aaaagagggt tcaggatttt ctgtctgtcc agtatatgct
    16381 agtattgatg agatagttga agtgagtaaa aaaattgcta gtatactaga acctctaaga
    16441 aataacccgc acgaagaagg cagaagaatg cattctatag gagtgataat cactccacct
    16501 aaagaggatg aagggaaata aatctgattt acatgaggta gagccaattt acacggaaaa
    16561 tcgttttatg atttacatat gtatccagag caaagtatct ctgcatggat tgtacttcat
    16621 tgtaccattt catccaatga cttggagtgg aacaatgaag ttttttaatt tttcatatta
    16681 atgcctaaag aaatgaactt tagaccacat atgcaattag gttacattat acaattagac
    16741 cagatataca gaataaaaat tagtattttt atagcagata aattgcctgt tattcttctt
    16801 aaaaatcatc tattagttat tgttagcata ttgaaagaaa ttatagtaat ctattgaata
    16861 aatgaatatt gcccataatc atataaactg ctatagttta aaataaagca ggacgttaaa
    16921 ttttatagta atcttaaaat ttaagagggg gattttatga aaataaaatt tgttattatg
    16981 ccattggtga tatttttaat agtattattt gtggggtgtc aaagtacaaa agatacagaa
    17041 gttaaagcaa aagatacaga aattaaaata ttaggtacag gtgatttgca ttcaattttg
    17101 acagactcta tggtttcata tgtaaatgag gaaagggaaa agaataaaaa tctgcttatg
    17161 gtagatgcgg gagacttcta tggtacacaa agtagagaaa tgtgggaatg gtcttctgga
    17221 aaaaagttaa ttaatattaa aagaaatggt agagcagagt atgatgacat aattaagagt
    17281 agtaaagatg aagtacctat agttaaagat atggcaaagt tgaaatatga tgctgtagtt
    17341 ttgggagata atgaatttat ttcaaatgat aagcaaagtc ttgataaact agtttctgat
    17401 tttaaaaata ataatatgcc attggtatca gcaaatatat atgaacaatc tggagaaaat
    17461 tatgtacaac catatgtaat gaaaaatatt aagacagatg agggcaatgt aaaagttgga
    17521 atactaggtc ttactataaa agaagtaggg gaaacccttg gtcttgagga ttttgaaaag
    17581 gataaaaaag ctagagagct tggagaacaa gctgattaca aaggaaaatt atatgcaaat
    17641 gatttagtag aagatgcaaa gaaatggata aaagttatgg aaaaagaaag tccagacata
    17701 atagttgcag ttgtacactc aggggaagaa cctaaaacag atagaaatct aggaaataga
    17761 ataaaagagt tagcaactac agtggatgga atagatgcaa ttgtagctgg tcatactcat
    17821 gaaaaaatag atgaacacaa atataaaaat aaatctggag atgaagtaat tgttacacaa
    17881 ccaggttggc atggagatag agtatcagag attaatttca aattaaataa agagaatgga
    17941 aagtgggaca taaaggaaaa gtctagtaaa ttaaaaataa ttgataaaga agtaagtata
    18001 gttgctactg cagatttaca ttcacatttc tctgataaat taacagttga ccttgttaat
    18061 gaacgtagta acccaattga acctgttgta gtagatgcag gcgacttctt agaccctcaa
    18121 acagatgaaa tgactcaatg gtataaagag tggaaaagta taagagataa taatagtgat
    18181 aaaacgatta gtagatgccc aatggtcatg gatatgaatc agggaatgta tgatgcagta
    18241 gtacttggaa atcatgaatt tgtatctgaa aaagatgaat tttggtcaga tgaacgcctt
    18301 ttagatgctg ttatagagga ttttgaacag gtggcaattt ctgtgttatc agcaaatata
    18361 tataggcaat ctggtaaaaa ttatgttaaa ccatatatta taaaagatgt ggagacgagt
    18421 gaaggtaatg taaaagtagg aatattggga cttactataa aagaagtagg taaaggtctt
    18481 aaaaatgtaa acttacaaga gcaatttcaa tataaggata aattgtatgc aaatgattta
    18541 gtggaagatg caaagaaatg ggtaaaagtt atgaaaaaga aaaaaccaga tataatagtt
    18601 gcagttgtac attcaggaga agaaccaaaa aatccaaaac acccaggaaa tagaataaaa
    18661 gagctagcaa ctacagtaga tggtattgat gcaattgttg ctagtcatac tcatgaaaaa
    18721 atagatgagc atgaatataa aaataagtct ggagaaaaag ttatagtgac acaaccaggt
    18781 gagcatggta aatattattc taaaattacc tttaaagtaa ataaagaaaa gggttcgtgg
    18841 attattaatg ataaattcag taaaacaatt gaggttgaat aactttataa aatttataga
    18901 taaagtaaat tatctgatat tgacatgata tataagataa agtttctaat attagtataa
    18961 tgcataatgt gaaatatttt aataataaga gaataaacaa gacaaataaa aatattttaa
    19021 catgtaagat atagtatgaa ctattatact aatgcttact ttataatttg aacatgttag
    19081 aataagtctt atttgaaaat tttagtgtat tagagtaagt attattttac cagtaaaaaa
    19141 tattgagaac tatatgtaga tttgcttaaa aaggaattta catatagttc ttttcgtata
    19201 ataaatagta caatcttata tggtaaagat aaagtgtgat attaaatttt attatcatcc
    19261 aaaatctaag gaggagtctc ttatgaaaat aaaatttatt atagtagcat caataatatt
    19321 tttaatagta ttacttgtgg ggtgtcaaag tactaaagac acagaaatca atgtactcgc
    19381 cacaagtgat ttacattcaa ttattccaga taatttaatt tcctatgtag aagaggagag
    19441 aaaatatgat gagaatctac ttatggtaga tgcaggagat ttttttgaca tgcaaagtgg
    19501 tgagatgaat aagtggttta ctggtcaaaa attagtaaga tttaaagatg ggataccaga
    19561 gtacaaaaaa atagctgaac cacgtgaagg agaagttcca ttggctaaaa aaatggcaaa
    19621 gctgaagtat gatgcagtta catttgggaa tcatgaattt gtatctaatg acaagcagag
    19681 ccttgataaa ttggtttctg attttaaaaa taacaatata ccattagtat cagcaaacgt
    19741 atatgaacaa tctggagaaa actacgtaaa gccatatgta atgaaaaata taaatactga
    19801 caagggaact gtaaaggttg gtatacttgg tctgactata aaagaagtag gggaacgttc
    19861 aaggtttaaa agttttaaac aagataaaaa ggctagagaa cttggggaac aacctcaata
    19921 caaagggaaa ttatatgcaa atgatttagt agaagatgca aataagtggg taaaggttat
    19981 ggaaaaaaaa gaaaagccag atataatagt tgccattgta cactcaggtg aagagccaaa
    20041 aaatcctaaa aatccaggaa atagaataaa agaactagca acaactgtag agggaataga
    20101 tgctattgta gcaggtcata cacatgaaaa aatagaacag catacatata aaaataattc
    20161 tggtgaagaa gtaatagtaa cacagcctgg agctcatggt aatagtatat caaagattaa
    20221 ttttaagttg gataagaaga atgataagtg gtttataaaa gacaaatata gtgaattaaa
    20281 ggtttttgga aaggaagtaa atataattac aacttctggt ctgaatccaa aattttcaga
    20341 tgaaatggca gttaatttgt ttaatgaaag agatagagat gttcaaccta tctttataga
    20401 tactggagat tttttaaata ctaatacaaa agaaatgact aagtgggcta aagagtggca
    20461 atacaatgaa aataaaggca tctataaaaa aataaatgaa tggccaattg tatatcttgg
    20521 ttatgatgct gtagtacttg gtagccatga atttacagag gataaagaga cttttgagga
    20581 aaaaaaatct acattggatt atattataga aaactttgaa gaaatgaaga taccagtatt
    20641 atcagctaat atatatgatg aatctggaga aaattatgta aaaccttata taattcataa
    20701 tgtagaaact agggaaggaa atataaaggt tggagtatta ggtcttacta ctactgataa
    20761 ggatgaagaa gacttaagta gatcaagctt aagcaaagac tcaaagactt cgaaaattcc
    20821 tgaagaaaca ggaaagttat atactaataa tctagtaaaa gatgcaagcg aatgggtaaa
    20881 agttatgcaa aaggaaagtc ctgatgtgat tgttgcagtt gtacattcag ataataatag
    20941 tactctaaaa aatccaagta gtgaagtcaa aaaacttgca atgtcagtag atggaataga
    21001 tgctattgtt gtaggtcata cgaaaaataa ggtagaagaa catatttaca aaaataagtc
    21061 tggagatgag gttatagtaa cacaatctgg agaagattgt tattcaaaaa taagtcttga
    21121 actaagaaaa gaaaatggca agtggaatat cataaacaaa tatagtaaag caataaaaat
    21181 gaagtgaatt tattgatata taaaccatta ttaacactga tttttataat ataataaata
    21241 ctgattctac aatataatta acactacttt ttataatgtc gtcaacactg attctataat
    21301 ataattaata ctactttttt aaatataatc aatactgatt ctataatata attaacacta
    21361 cttttttaaa tataataaat actgattcta caatattatt aatactactt tttataatat
    21421 aatcaatact actttttaca atataatcaa tactactttt tacaatataa tcaatactga
    21481 ttctataata taattaacac tactttttaa atataatcaa taccgattct ataatattaa
    21541 cactattttt tatgctatat aacaattatt gaaaatgata taagtataat atctcaaatg
    21601 atatgaatat aacatctgaa tagagggtgt tttatttgta aaaaataagt ttacagtttg
    21661 agcgtataaa cttatggtaa aggagaataa ttatgaatta taagaagatt gcaattataa
    21721 cgggtgctaa tagtggtttt ggtaaagagt ttctaaagtt attaataaat gaagaagaaa
    21781 taacagaaat atgggcagtt gcaagaaaca aggcgagatt aaatcaatta gtagatgaat
    21841 ttggaagtaa ggtaaaagtt ttttcaaaag atttatcaaa aatagaagaa gtaaaagaaa
    21901 ttggtacatt tttaagtaaa gaaaatgtat gtataaaata ccttataaac aatgctggtt
    21961 ttgcaaaatt ctgttcatac aatgatttaa gtatagatga atctattaat atgattgatt
    22021 taaatattag tgctgttgta gcattgggac ttatatgtat tccatatatg caaaagggaa
    22081 gccatatcat gaatatttct tcacaagcat cattccagcc attgccatat caaaatattt
    22141 atagttcaac taaagcgttt ataagaaatt atacaagagc attaaatgtt gaacttaaga
    22201 gtaaagggat aaatgcaatt gctgtatgtc caggttggat gagtacaaat ctatttaaga
    22261 gaggtatagt tgtagctgaa aaagggacaa aaaatttccc aggcatagtg tctccagacg
    22321 ttgttgccaa aaaagcattg aaggatgcaa agaaaaataa ggatatttct gtgtatggta
    22381 taaatacaaa atccagtcat ttattagcga aactattgcc acaaaaaatg atgatgaagg
    22441 tttggttaat gcaacaacat attaaggaat aagagtttcg gtaattaagt atcagttgga
    22501 gattcaatct attatatatt ataagaagtt ttgttgagca aataataatt gtgacaaaac
    22561 ggcttatcta gtgccgataa gccgtctata atgtatataa aatatatttt tgattttact
    22621 ttatttatat attgaagtat taaaatatgt aggacttgaa attttataaa gataaatact
    22681 atgatatttt gtaaaaactg cgatatgttg atatcacata gtttgactat actgttaaat
    22741 tgaagttttc ttattttgca ttatgcttat tacttaatga tttagactat aatttccata
    22801 ccatcatatg caaaataaat gttatcaagt ttcttttcta attcactgta ataaccatat
    22861 gattttcccc acatttcgtc aatatgtgta atgataatct ttttaattct ataatagttt
    22921 ttaatttcaa caatctcatc taaagtaaat atttcatctt taaatggtgt gtctttaagt
    22981 tttgtaccat catttaatat accatcatca gaaactagac ttattattaa aacatcagca
    23041 tcaaagtaca tatcactatg agtaaatggc ttgggattac agcaggcata tatgactttt
    23101 ttttcattct ctttgataac atagaaggtt atattcctgt ctgggttatt gttaatcaaa
    23161 tcaatatcaa aattatttat ctttacatgc gaagtttcat taatagaaat gcaatttata
    23221 acatcaccat aatatttaag acaatcgaga ttcgttcggt ttatatcttc aattacttca
    23281 ggaagagcat aaaagccaat tggattattt tctcctgtga taaagtcaca tcctattttt
    23341 tcgacaattc taataccctt aacatggtct gggtcatggt gagaaattga aatatgtttt
    23401 acttccgata ttttttgtct gttacaagct actgcaatat cttcaggtgt gtctatcagc
    23461 atttttatat catcaatata taaacttggt cctaatcgtt catatcttcc gcctttttgc
    23521 ctggcttctt cacatatttt gcatttacaa aatgaacttg gaataattga cataccgcca
    23581 ctaccaacaa tttttaattt caaagttatt acaccacctt ctaaaaatat tagattatat
    23641 aaataatcta caatcataac tgattaacaa aattatgagt taataaatta tatcacatgt
    23701 aaatatgaaa gaatagtatg aaatttttat aagattatat taaatatttc tcaatgaaat
    23761 tgactttgta tatgagccga atgactttat tcaatataga taagacattt ttcttgtaat
    23821 aagatatgat tattctataa ggttcatgta attttgatat aatatattga ttaataacat
    23881 atatgttatt ggtgaacata tttctataga atggaatata taatttttta tatttatcat
    23941 tgtattattg tacaaagaaa gttaaaaaga gtagagtaca aaggaattat ttgtacttta
    24001 ctctttgttt tgttaaaaac taatttatat tagtgattca aatatttaac tagagtataa
    24061 gggttgtata taatcttata agtaatttat ctgacaaatt aagataatat cctaattaaa
    24121 ttgtaggtat ttatacataa tactaaaagt aatttgtcta acaaattaaa atattatcca
    24181 attaatataa aaattacttc tttttaactg ggaagcatac ctctgttacc caattatcag
    24241 gattactatc gttgccagga cttacatgat aaatattaaa cataggacca tccacatcat
    24301 agttattatc tgatatccaa ttaccaatag cctcacaagc gtctgcaact tgattgaaat
    24361 ttccattaac aattgcagtt gcagcagtca cacttggaac agtcttaaat ttaacatgtt
    24421 cagtatcttt atactttcca gatacagcaa cttgtacttc aacatctaca taatcttctt
    24481 tatatccagt atcataaaag actgctttag aatactttgg gggttcaatt tgaacattct
    24541 ggtcttttgt ctctaaaaat gcttgatgcc ataacattcc ttcgtcttga taagttggta
    24601 taacccttct aagtgtcatc atatattttg gtgcaaaatt ctttatagtt acatcataat
    24661 ttttcataat gtcatttcct ccaattcttt taatagtggt ttctattttt aatagttttt
    24721 tctgtgtatc ttctaattgt tcttttactt gagaatggtg gatatttaga tattttatga
    24781 gactttcttt atcgttatat tctgtcaaaa tttcttttat agaatacaag ccaaagccca
    24841 tatcttttag tgcatggatt ctgtttgtag tagaaagttg gtctgcacta tagtatctat
    24901 atccattagt tttattcgta tgagaaggag ttaaaagtcc tatttcatca taatgacgta
    24961 acatacgaat actaatttta cttagctttg aaaaatcgcc tatcttaaac atgtttttgt
    25021 ctcctttata aaggtacttt tagcttaata ttaatataaa ccatatcata atgttagagt
    25081 caactaaaat tataattaaa ttatattgac atatgatgaa aaaaatatta tactgaacat
    25141 gttcagaact gaaaatgtta attgttttgg aggtctatta tgaaaagtaa tgataaagat
    25201 gctagagaac gtataattga agttacattg aatcttttaa atgaagtaga tgatattgag
    25261 gaaattacag ttagaaaaat tgctgagcgt gcaaatgttg gagttggttt aataaattat
    25321 cattttaaaa caaaggataa tttgttgagt actgccatag gagatgtgat gtcaaatata
    25381 atagcagagc tatatgacga tagtgtatat actctaagac ctattgaaga tttgaaaaat
    25441 ttattaaaaa aattgtgtga tactggatta cattatgaaa aagtgcttcc ttttgtgttg
    25501 aatcaatgta taaccaatgg agatatgcaa gcagaacttg atattgtccc tatgcttcgt
    25561 aaaatttttg gaaataaaaa agatgaaatg agtctaagaa tcattgccct gcaaattatt
    25621 ttaccaatac agatttctgc tttatctaca gaatcatttc agttatacag tggtataaat
    25681 ataaagaata aatatgagcg agataaattc attgatattt taatagaaaa tattattgga
    25741 gaggatgttg atgtaagatg aaaattataa ctattggttc aagtcttatc actgttttac
    25801 tttttctttc aactatggtt tgtgggttct ggattaagaa taataaggta acagatgcaa
    25861 gttctattaa gttccatatg aatagtgcta
//
LOCUS       DACTZW010000058        25848 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.058, whole genome shotgun sequence.
ACCESSION   DACTZW010000058 DACTZW010000000
VERSION     DACTZW010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25848
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.058"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(56..1459)
                     /locus_tag="JAM15_12520"
     CDS             complement(56..1459)
                     /locus_tag="JAM15_12520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp9"
                     /protein_id="HAT6799076.1"
                     /translation="MKNSKKILAIGLTLFLVMVNTPMVNALTSVEQIKGNDRYETAAK
                     IADKQNYNTAILINSDNSLADGLSASGLAGALNAPILMTKQNQIPNITMERLNKAKTV
                     YIIGSESTISKNVENQLLSKKKVVQRIFGENRFDTSIKIAEKIKEIKPIDKVIIANGF
                     TGEADAISASPVAARDGVPIILTDGNSVGFDTTGLKSYALGSSEIISDELVKSTNSIR
                     LGGTDRFETNKIVIQEFYKNSKEFYLSKGLQLTDALAASTIAKNAPVVLVENGSNKSI
                     LSGADKLTVLGGINQNVIKQCINQASPNQQGLYYNPNDRAFKERIKGKVYALTKQYRK
                     ENGVRALSVASRLEGLANDWSNLMANKKTLSHTINGKNSYSTFLKYLDWSEIKPGYIA
                     VQGENIIKYKIPDKPVYTNRDADDIGNFIFNEWKTNPEEGTNMLHKGYEIMGFGIAIT
                     GDKNLYATHEFYGRYKE"
     gene            complement(1921..3816)
                     /locus_tag="JAM15_12525"
     CDS             complement(1921..3816)
                     /locus_tag="JAM15_12525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp8"
                     /protein_id="HAT6799077.1"
                     /translation="MLSNKKRSMAIVMAGATAMSAAAPIFADNTVTENVDKNYTVSAK
                     DSAKLIEEVRKALEVKFEDTKAGANVNDRVYDIKVDNVNLTNATQLQNKINSLTEGQS
                     LKVTIQDKGHQVLGGKVVDYKIENYKTAQEIVEAVNAYNATLAEDSDNKLTATIKSTN
                     TVEVKRAKDSANVITLNVGDQHLDFSKVITSEEGTFEGYEKSYSDIDSKELHTITVKN
                     ADLQDISAEELFDGIRLTTLGREIVNKVKNGYALTFENEAILTQEQEDSDDKDKPEKS
                     SFDIVLSKANEKPETISVSSKNHKLVRDLHKVLTDVKDGKELKVEVLSGDSRFTTAVE
                     VSKERFKDGEAEAIILVGEDAIVDGLASAPLASQKNAPILLSKKDSLPSEIEAEILRV
                     LGSNLSSKKIYIVGGESKVSKETEEKLSKLGVSKVERVSGEDRFETSLEIAKQLKDTF
                     KTAFVVGGNGEADAMSISARAAQFGAPIIVTGNELDANAEKLLKGKELEIVGGENSVS
                     KEVEDKLVDIDLNNKVERLAGENRKDTNAKVINKYYAGATKAYVAKDGYVGGNGQLVD
                     ALTAAPLAASSKAPIVLTTEELSKSQEEVVELRLKNATKLVQIGEGIAKNAIEKIAEK
                     INLFTKN"
     gene            complement(4441..4584)
                     /gene="scfA"
                     /locus_tag="JAM15_12530"
     CDS             complement(4441..4584)
                     /gene="scfA"
                     /locus_tag="JAM15_12530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007789995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="six-cysteine peptide SCIFF"
                     /protein_id="HAT6799078.1"
                     /translation="MENKHVKTLSQATLKQSAAKGGCGECQTSCQSACKTSCTVANQE
                     CER"
     gene            complement(4650..5012)
                     /locus_tag="JAM15_12535"
     CDS             complement(4650..5012)
                     /locus_tag="JAM15_12535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04086 family membrane protein"
                     /protein_id="HAT6799079.1"
                     /translation="MGKSNYIFKGLGYAYIITLAVLLVYNLFLTFTDIGGDNITMVSS
                     FITTISAAIGGFYTSKHMKEKGLMYGLLVGLLYIVCIFLTVFLAQEKFVFEVGMIYKL
                     LLISAAGGIGGVLGVNFK"
     gene            complement(5070..5363)
                     /gene="yajC"
                     /locus_tag="JAM15_12540"
     CDS             complement(5070..5363)
                     /gene="yajC"
                     /locus_tag="JAM15_12540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HAT6799080.1"
                     /translation="MPQQQIIMSIGLWVVVIAIFYFLMIRPQKKKDKQLKEMRSSLSV
                     GDKVITIGGIVANVAKVEDDVVILELGPNRTKVPFEKWAIGTVQSKKEEIEED"
     gene            complement(5497..6618)
                     /gene="tgt"
                     /locus_tag="JAM15_12545"
     CDS             complement(5497..6618)
                     /gene="tgt"
                     /locus_tag="JAM15_12545"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HAT6799081.1"
                     /translation="MYAVRYELIKTCKQSGARLGRLHTPHGIIETPIFMPVGTQATVK
                     SMTPEELKEIGSQIILSNTYHLYMRPGHELIKRAGGLHKFMNWDKPILTDSGGFQVFS
                     LGPLRKIKEEGVEFRSHLDGSKHFLTPEKAMEIQNALGSDIMMAFDECAPYPSDREYV
                     KNSLERTTRWLKRCKDAHNNTDKQALFGIIQGGMYKDLREQSAKEITNIDLPGYAIGG
                     LSVGEPKPLMYDVLEHTTPLMPKDKPRYLMGVGSPDDLVEGVIRGVDMFDCVLPTRIA
                     RNGTAMTSQGKVVVRNATYAEDFTPLDPECDCYACKNYSRAYIRHLIKANEILGARLI
                     TTHNLHFLLNLMKQIRQAIMEDRLLDFRNEFFAKYGYEI"
     gene            complement(6697..7182)
                     /locus_tag="JAM15_12550"
     CDS             complement(6697..7182)
                     /locus_tag="JAM15_12550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799082.1"
                     /translation="MHSLQKQKKNNPILKIAFIFERILAVVVLIAVFLGTIDILRLMW
                     GAYIVDFQNPVQYSQLNDFLAQILLLVIGVELVVMLSLHIPGAFIEALLYAIARKMLL
                     LPKNEGMIDVLIGVIAIAGLFAIKKFLVTKDKSALNIMSIHDEEAIKEQQNKEDEDKS
                     I"
     gene            complement(7194..8219)
                     /gene="queA"
                     /locus_tag="JAM15_12555"
     CDS             complement(7194..8219)
                     /gene="queA"
                     /locus_tag="JAM15_12555"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007286273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HAT6799083.1"
                     /translation="MKTSDFKFDLPQELIAQVPIEDRASSRLMVLDKETGNIEHKVFR
                     DIIEYLNPGDCLVLNNTRVIPARLIGEKLETGGKIEFLLLKRTEEDTWQSLVKPGKRA
                     KVGTKFSFGNGKLIGEVVDLSDEGSRIIKFHYDGIFEEILDELGNMPLPPYITARLDE
                     KERYQTVYSKHNGSAAAPTAGLHFTEELLNKIKEKGVDIAFVTLHVGLGTFRPVKVED
                     VLSHKMHSEYYMVSQEAADKINRAKENGNNVICVGTTSCRTIESACNEDGKMKETSGW
                     TEIFIYPGYKFKVLDKLITNFHLPESTLIMLVSAICGKDNVLNAYNEAVKERYRFFSF
                     GDAMIIK"
     gene            complement(8537..9556)
                     /gene="ruvB"
                     /locus_tag="JAM15_12560"
     CDS             complement(8537..9556)
                     /gene="ruvB"
                     /locus_tag="JAM15_12560"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HAT6799084.1"
                     /translation="MQGFEDENRIITSTMKMEDIDIENSLRPKTLEDYLGQEKSKEQL
                     SIFIEAAKSRNEQLDHVLLYGPPGLGKTTLASIIANEMGVNLRITSGPAIERAGDLAA
                     ILTNLNENDVLFIDEIHRINRSVEEVLYPAMEDFCLDIIIGKGPSARSIRLDLPKFTL
                     IGATTRAGMLTNPLRDRFGVICKLDYYTVDELSKIVLRSSSILDAEIQSNGALELAKR
                     SRGTPRIANRLLKRVRDFAQVRADGKITDKVAKDALELLGVDSLGLDFVDEKLLMTII
                     EKFRGGPVGLDTLAASIGEDRNTIEDVYEPYLLQLGFINRGPRGRVAMPLAYEHLKIP
                     YPNEK"
     gene            complement(9663..10265)
                     /gene="ruvA"
                     /locus_tag="JAM15_12565"
     CDS             complement(9663..10265)
                     /gene="ruvA"
                     /locus_tag="JAM15_12565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HAT6799085.1"
                     /translation="MYSYIKGTVEEIYIDSIVVENNGIGYKINVSSNTIMNLQVGEAT
                     KIYTKLIVREDDMSLCGFVSREELKMFELLTSVSKIGPKVALSILSFASPAQLGAYIL
                     SEDIGKLSKAPGVGKKTAERIVLELKDKVDKNNIEFEPTLLSQKPTLISQDESVDALV
                     ALGYTLSESKEAVQKCKKDGMNTEAIIKKALTYIMSKSLK"
     gene            complement(10258..10767)
                     /gene="ruvC"
                     /locus_tag="JAM15_12570"
     CDS             complement(10258..10767)
                     /gene="ruvC"
                     /locus_tag="JAM15_12570"
                     /EC_number="3.1.22.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HAT6799086.1"
                     /translation="MIILGIDPGIAIVGYGIIEYKNSKFKAIDYGAVTTPAHMNISRR
                     LELVYKGIDTIVKNYNIDEVGMEELFFNKNVKTAITVAQARGVTMLACAHNGKPVYEY
                     TPLQVKQGVVGYGRADKAQVQQMVTSFLSLKKVPKPDDVADALAVAICHAHSNKLEKT
                     LKNIGGKYV"
     gene            complement(11051..11680)
                     /locus_tag="JAM15_12575"
     CDS             complement(11051..11680)
                     /locus_tag="JAM15_12575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799087.1"
                     /translation="MFEKKKKELFPWKISALILVGVFVLSSGVYIGTRLKNNGVQTGE
                     VVSASANMDEKSKEAFGLNKNCEVWLQSEGENETNYKRTLTMAGIVPESLLDKTKSEI
                     VSYFKKEYPTKKIKSMDKNEIILVESKYSDNKDVQAMNATIKGKYTIENDNGNIALYK
                     YDDSGSKTLVEKTKIRVDSLPKTVQDEIKKGVVMDTEEEAYSRLEDFAS"
     gene            11883..12206
                     /locus_tag="JAM15_12580"
     CDS             11883..12206
                     /locus_tag="JAM15_12580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HAT6799088.1"
                     /translation="MERINCNVINCSHNNSHICYADKIFINGEKAHNDRHTCCSSFLD
                     ESIYSNLSSNVNNRNCEELVCTVKNCKYNKDGSLCTLDNILVAPETDRVNLYIETCCS
                     SFECK"
     gene            12474..13328
                     /locus_tag="JAM15_12585"
     CDS             12474..13328
                     /locus_tag="JAM15_12585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799089.1"
                     /translation="MSTFYIQFLYFVIYSFIGWCCETTYCSVLQKQFVNRGFLNGPFC
                     PIYGFGALAIVATLTPFVQNIPLLFLFSIIITSIMEYFTSFILEKIFNMTWWDYSKHK
                     FNIHGRVCLENSLMFGVLSLIVMLIVHPIVVDFINSISKNVLFIFAISIEIYFVLDLV
                     ITVHTILQLNGKLKQINLIIKELKDKKEYYKLITQETIENKLESLVENRLDTLEDRFE
                     ILKEKENYRYAKNRIDELKNKLNTLLSNHKLLHRRIIKAFPNISSNKHTDILNKIKEN
                     IKSIKKDK"
     gene            complement(13514..14950)
                     /locus_tag="JAM15_12590"
     CDS             complement(13514..14950)
                     /locus_tag="JAM15_12590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HAT6799090.1"
                     /translation="MREVKPISIDILNTFKQVDEDRLNELLADELKHLDRKIVVLDDD
                     PTGVQTVHDISVYTDWDKDSMEQGFNEKNSMFFILTNSRGFTVAQTTKAHKEISKNIV
                     DVSKKVNKDFIIISRSDSTMRGHYPVETNLLKSEVERLSGKLFQGEIIMPFFKEGGRF
                     TIDNVHYVKEGEILVPAGMTEFAKDKSFGYKSSDIGEWCEEKTHGKYKSSDMIYISSK
                     ELRELNIEAITEKLKKAEGFNKIIVNATDYVDVKVFTIAFIRAVNSGKEFMFRSAAAI
                     TKVLGGVSDKEMLTKDELVSKGNTNGGIILVGSHVNKTTQQLEELKNCKYPIEFIEFN
                     QHLVLQENGLKNEVKRVIKVVEEKISSGKTVAVYTRRERFDLDTNDKDKQLMISVEIS
                     DAVTSIIGMLNVRPNFIIAKGGITSSDVGTKALRVKKATVMGQIKPGIPVWMTGKESK
                     FPNMPYIIFPGNVGEISTLRESVEILMG"
     gene            complement(15021..16403)
                     /locus_tag="JAM15_12595"
     CDS             complement(15021..16403)
                     /locus_tag="JAM15_12595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HAT6799091.1"
                     /translation="MITGYGLLIAFVISIGILLISIIKFKVNPFLALLITSIITGFMV
                     RMPINEISTTISTGFGNTLGSIGIVIGLGIIFGNILSESRATESIAKGLLAKTGEKNS
                     ALAVTTAGFLISIPVFMDAAFVIMMPIIKYVSRVTKKSLMVFVCALGVGTIVGHALVI
                     PTPGPLAVAANVNANVGSFILYSIIVAFPAALIGGWIYGKRFEKYPAYAIDENDREKN
                     LEQGKDSIKIEDDDSSKVPGFGISMFSLLFPILLILISNVFSMFLEKGSTMSGVLAFI
                     GDKNIAILLGILVAIGFLKKYINKPMGDVVIEAADSAGLILLITGSGGAFGSVINASG
                     IGNFLVDTMSGLSISVVVLGFLLSALLRISQGSATVALVTTSSILGPTILATGMSPVL
                     VGLAICAGGVGFSLPNDSGFWVLSRFSGLSVKDTLNSWTIGGTIAGVVAFIMVLLLSV
                     INGIIPLPGL"
     gene            complement(16539..17444)
                     /gene="garR"
                     /locus_tag="JAM15_12600"
     CDS             complement(16539..17444)
                     /gene="garR"
                     /locus_tag="JAM15_12600"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HAT6799092.1"
                     /translation="MEGYKMKLGFIGLGIMGKPMAKNLLKDGCNLLVYDINKSAVDEL
                     ISCGAKYASVLEMGQECDIVFTILPNGTIVQDILFGMDGLAKTLKEGSIVVDMSSVTP
                     TESILCANKLKDMGLEFIDSPVSGGEPKAIDGTLAFMAGGKEEIYKKVEPFFNIMGSS
                     SILIGDNGSGSVTKLTNQVIVNLTIAAVSEAFVLAAKAGADPEKVYKAIRGGLAGSTI
                     LDAKIPMIMNRDFKPGGKISINLKDIKNVMQTAHNLDVPLPMTSQLLEIMQTLKVHGH
                     LEDDHSGIAQYFEKLAGVEIKKHNN"
     gene            17839..18510
                     /locus_tag="JAM15_12605"
     CDS             17839..18510
                     /locus_tag="JAM15_12605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAT6799093.1"
                     /translation="MATFKRLQEQAYDYLKELILSGEMIENEIYSETKLASEIGISRT
                     PIRDALQRLSQDGFIDIIPSKGFRIHQITANEIVEIFQIRSAIEGFCTFLITSQYKES
                     RAVETISKLKYLLDKQKDILLGDKNLNSFAEYDTLFHTTIVSYAQNTEFDKMFNNYMY
                     RIKKLALDSLSHEGRLETTLKEHTDIFNNIANGCIEDVYKTTLIHMETPKYINLEDFC
                     NNKRF"
     gene            18621..19160
                     /locus_tag="JAM15_12610"
     CDS             18621..19160
                     /locus_tag="JAM15_12610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799094.1"
                     /translation="MNENVVTNETIDKDYAIEEVRMACKHFGDLYFYFSKVLFEEFGE
                     DKTSEILRKVLFERSEERAIAMRERALENGDELIADNIISTTDVPFLGWVPEFKELHC
                     PYGASWLLRFEENPWFKKFASLYCDVTDTTVAEVFTGDTSHKITKNILWGDKSCERIY
                     FHDDKVSEGKYTYGNKNCK"
     gene            19422..19730
                     /locus_tag="JAM15_12615"
     CDS             19422..19730
                     /locus_tag="JAM15_12615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799095.1"
                     /translation="MFNKIYEKKEFIVFQVKKGYVVYNTRKSFEEGHTHLKHFEAAKT
                     AIDLAINKKIPRSKDGYYLTSLIRISDDGYYIDKLSELLYVREQKGKKEKYCNSGYQM
                     "
     gene            complement(19892..21682)
                     /locus_tag="JAM15_12620"
     CDS             complement(19892..21682)
                     /locus_tag="JAM15_12620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6799096.1"
                     /translation="MKKSKGFKKTIGRLLPFVKKYKFSFIIAIICIISAATMNALAPK
                     TEGLIITQLTKDVISIAKGVPGASVNFDYVTKILVILACIYFANAIFTYTSSFLLTNA
                     IQNTMRDLRNEVENKIRRLPISYFDSNSFGDVLSRISNDVDTISNALQQSFMQIVNSI
                     LVIILALSMMFTINIYMALIALFIIPISYFVSKFVVKKSQSRFSLQQNALGKLNGKVQ
                     EMYTGFNEIKLYGKEEDSIKEFKKVNQELCENGFKAQFISSMMNPMVSLVTYFGIAAV
                     AVVGSIYAVSGGITVGNLQAFVRYIWQINQPLSQMTQLSTVIQSSFAAIERVFEILDE
                     EEEIPDVENPVKIENVKGNVTFEHVNFGYGENSTLIEDLNAEVKSGQMVAIVGPTGAG
                     KTTLINLLMRFYDVKKGAIKIDGVDIRDMKRKDLRSMFGMVLQDTWLFNGTIFENIEY
                     GRFGATKEEIIQAAKVANVHHFITTLPDGYNMFLNEEASNISLGEKQLLTIARAFISD
                     PSILILDEATSSVDTRLELMLQKAMRNLMNGRTSFVIAHRLSTIRNADLILVMNNGSI
                     IEQGNHDELMEKGGFYEKLYNSQFADKESE"
     gene            complement(21682..23409)
                     /locus_tag="JAM15_12625"
     CDS             complement(21682..23409)
                     /locus_tag="JAM15_12625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012198132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6799097.1"
                     /translation="MKLILSYLKNYKLLIVLNILAIFSFALVELGIPTIIAKIIDNGI
                     ANQNIAYIKQMGIVIVIISIIGVVGSILLGYCSAKVSTSVTRDIRNDIFEKSQEFSHT
                     EYNKFGISSMITRTTNDAFQIQQFVNILLRTALLTPVMFIISIIMTIRTSVELSIVLA
                     ISVPFIIIGVAIIAKVSQAISSKQQKGLDKLNLISRENLTGIRVIRAFGNDDYETERF
                     EKTNTYYANVSKKLFKLMSITQPAFFLLLNIAVLAVFWISSEKINIGELQVGQLVAFL
                     EYLFHAMFSIMLFSMVFIMYPRAEVSANRIKELLNEEPLIKNPENGIKDTESKGIIEF
                     DNVTFTYPDGEASVLKDISFTAKTGETVAFIGSTGSGKSTLINLIPRFYDVTEGSIKI
                     NGVDIREYDLKALRKKIGFIPQKSLLFTGSIANNIRFGKHKAGESELEYSAKVAQAYE
                     FISKKPRKFDELISEGGANVSGGQKQRLSIARAIIRRPEIYIFDDSFSALDFKTDAIL
                     RAKLKKETKDAIVLIVAQRISSIIDADKIIVLNEGQVVGMGTHKELLKNCEIYYEIAT
                     SQLKKEELE"
     gene            complement(23654..24217)
                     /locus_tag="JAM15_12630"
     CDS             complement(23654..24217)
                     /locus_tag="JAM15_12630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAT6799098.1"
                     /translation="MLEVVNMRKVVLYIATSLDGYIAEENGSVSFLDEISSEFKNEQE
                     DDYNTFYDTIDTIIMGNSTYVQIANELSPNEWYYKGKECYIYSNTINGTTENVKYTNL
                     EPKKLIEQIRKEKDKKDIWIVGGGDIVKLFMKDNLIDDYYIYILPIILGRGISLFKSG
                     IDKTNLNFKKASNIGELVKLEYSKKQK"
     gene            24515..25627
                     /locus_tag="JAM15_12635"
     CDS             24515..25627
                     /locus_tag="JAM15_12635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino-acid racemase"
                     /protein_id="HAT6799099.1"
                     /translation="MKISEVATPNFLLDLDQLEKNIDKIQQICTNNNKQLWPMLKTHK
                     STYIARLQKNAGASGFLVGTLDEGEALIKAGFEDIMLAYPYMGEVNINRIVTMASKIN
                     LICATDNIECAKAYSEAFSKSKIECKLLIIVDCGLHRFGVEPEKVVELATEISKLENI
                     KIVGISSHPGQVYGCSSPEDVPDVCVQEDSSMEKAYKALTDNGFNIEIVASGSTPTVE
                     AEAASKTITAVRPGNYVYYDAIQIGLGCATEDMCALTVVCTVISKNSSGYYLIDCGSK
                     CLGLDKGAHGNSSIVGYGRVCGHPELTIDSLSEEVGKIKVNGETDIKIGDRIRIIPNH
                     SCSTANLTSNLLGFRGDTIEKVIEVDIRENSKQIIL"
BASE COUNT         8424 a         4438 c         3018 g         9968 t
ORIGIN      
        1 tataatttaa ttatttatat agcttcctta caagcataat tttgtgtata ttttcttatt
       61 ctttatatct tccataaaat tcatgtgtag catatagatt cttatctcct gttatagcta
      121 taccaaatcc cattatttca taccctttat gcaacatatt agttccttct tctggatttg
      181 tcttccactc attaaaaata aagtttccta tatcatctgc atctctattt gtatatacag
      241 gtttatctgg aattttatat ttaattatat tttcaccttg aactgctata tatccaggtt
      301 taatctcact ccaatctaag tatttcaaaa aagtagaata tgaatttttt ccatttatcg
      361 tatgagataa agtcttctta tttgccatta aattagacca atcatttgct agaccctcta
      421 atctgcttgc tacagataac gctcttactc cattctcttt tctatactgc tttgtaagag
      481 catatacttt accctttatt ctctctttaa atgctctatc atttggattg taatataacc
      541 cttgttgatt tggtgaagct tgatttatac attgcttgat aacattctga tttatgcctc
      601 ctagtacagt caatttgtct gcaccactta aaatactctt gttactgcca ttttcaacta
      661 aaactacagg agcatttttt gctattgtag aggcagccaa agcgtctgtt aattgcaagc
      721 ctttacttag ataaaattct ttactatttt tataaaactc ttgtataact atcttattag
      781 tttcaaatct atctgtgcca cccaatctaa tagaatttgt gctcttaact aattcgtcgc
      841 tgattatttc actagaacca agcgcataac tctttaagcc tgtcgtgtca aatcccacac
      901 tatttccatc tgtaagtatt ataggtactc catctctagc agctactggt gatgcactta
      961 tcgcatctgc ttctcctgta aatccattgg ctataattac tttatctatt ggcttaattt
     1021 ctttgatttt ttcagctatt tttatacttg tatcaaatct attttcacca aatattcttt
     1081 gtacaacctt ctttttggat agtaactgat tctcaacatt tttacttatt gttgattctg
     1141 agcctattat atatacagtc tttgctttgt ttaatctttc catagttatg tttggaatct
     1201 gattttgctt tgtcatcaaa ataggcgcat ttaaggctcc agctaaacca cttgcactta
     1261 gaccatctgc taagctatta tctgaattga ttagtattgc tgtattgtag ttttgcttat
     1321 ctgctatttt tgctgctgtc tcatatctgt cattcccttt tatttgctca actgatgtca
     1381 acgcatttac cataggagta tttaccatta ctaaaaatag tgtaagtcct atagctaata
     1441 tctttttact attcttcata ttattttcta cccccaatgt acttttcata ttttttatta
     1501 gtactcatac ttatttttaa tcaaaagtta caattttgtt accatatttt atatatgata
     1561 ccatagttat ccatacaact caaacaatat acctaaagtt tttattctct ataaattcaa
     1621 aacattataa tttattttat ttaattaagt tataagttca aaataattta tgttagtaat
     1681 atgtttaatc attataagaa gtatcttttt ataataattt ttgcaatatg aatttctcca
     1741 cattataatc aaaaaataaa ataaggtatc tcaatctaat tctaaatgag acaccttatt
     1801 tttattattt tatcttgtta tttgtatatt ttataatatc tacactatgt cttacatatt
     1861 aacgcattgt ataatcatat attatctaaa taaactttta atattaattc ctatatctta
     1921 ttagttctta gtaaataagt ttattttttc tgctattttt tcaatagcgt ttttagctat
     1981 tccttcacct atttgtacta acttagtagc attcttaagt cttaactcaa ctacttcttc
     2041 ttgtgattta gaaagttctt ctgtagttaa tactattgga gcctttgaac tagctgcaag
     2101 tggtgctgct gtaagtgcat caactaattg tccatttcca cctacataac catcttttgc
     2161 aacatacgct ttagttgcac ctgcatagta cttattgatt actttagcat tagtatcttt
     2221 tctattttct ccagctaatc tttcaacttt attatttaaa tctatatcaa ctaatttgtc
     2281 ttcaacttct tttgatacag aattttctcc acctactatt tctaattctt ttccttttaa
     2341 taacttttca gcatttgcat ctaattcgtt acctgtaact attattggag caccaaattg
     2401 agcagctcta gctgatatac tcatagcatc agcttctccg tttccaccta ctacaaaagc
     2461 agtcttaaat gtatctttta attgttttgc tatttctaaa gaagtctcaa atctatcttc
     2521 tccagaaact ctctcaactt tacttacacc taatttagaa agtttttctt cagtttcttt
     2581 tgatacttta gattctccac ctactatata tattttctta gaagatagat tacttccaag
     2641 tactcttaat atttcagctt ctatttctga tggtagtgaa tcttttttag ataataatat
     2701 tggtgcattt ttttgagagg caagtggtgc tgatgctaat ccatcaacta tagcatcttc
     2761 tccaactaaa attatagctt ctgcttctcc atctttaaat ctctctttac taacttctac
     2821 tgctgttgta aatcttgaat caccagataa aacttctact tttaattctt ttccatcttt
     2881 tacatcagtt aatactttgt gtaagtctct aactaactta tggtttttac ttgaaacact
     2941 tattgtttct ggcttttcat ttgccttgct taaaactata tcaaagcttg atttttctgg
     3001 tttatcttta tcatcactat cttcttgttc ttgagtaagg attgcttcat tttcaaatgt
     3061 taaagcatat ccatttttaa ctttattaac tatttctctt cctaatgtag ttaatctaat
     3121 tccatcaaat aattcttctg ctgatatgtc ttgtaaatct gcgtttttaa ctgttatcgt
     3181 atgtaattct tttgaatcta tgtcactata actcttttca taaccttcaa aagtaccttc
     3241 ttctgatgtt atcacttttg agaaatctaa atgttggtct cctacattta atgtaataac
     3301 atttgctgaa tcttttgctc tttttacttc aactgtattt gtagatttta tagttgctgt
     3361 taacttgtta tcagaatctt ctgctaaagt tgcattgtaa gcattaactg cttctactat
     3421 ttcttgagca gttttgtagt tttcaatttt atagtcaact acttttccac ctaatacttg
     3481 atgtccttta tcttgaatag taacttttaa actttgccct tctgttaaag agtttatctt
     3541 attttgtaat tgagttgcat tagttaagtt tacattgtct acttttatat cgtaaactct
     3601 atcatttaca tttgctcctg cttttgtatc ttcaaactta acttctaatg cttttctaac
     3661 ctcttcgatt agtttagcag aatctttcgc acttactgtg taatttttat caacattttc
     3721 tgtcacagta ttgtctgcga atattggtgc tgctgcactc atagctgtag cacctgccat
     3781 tactattgcc atacttctct ttttgttgct taacatattt atgtcctccg aatattattt
     3841 tttatttttt atattcgtat ttcccacaca taaataatat tatatataat attatttttc
     3901 aatacatttt atgtgtttac ataatttact aacacaaaca ctaataatat cttcttgaac
     3961 cctttcccct acttagctat atataattat gctcaaagat agaaatccta ttttatagtt
     4021 attttctact aaacaatcat atactaacaa aagtattcaa actccatttt tatatactac
     4081 tatgcactaa tttttgcttt actcttatta cttaaatata tatcactaaa ttaatatcta
     4141 tctccatata ttaaaatata taacatatta taaaaatcat cataaattag agtttaaaat
     4201 taaaaattat tctaatacat gtaattgata aaaaataaaa tataagagta gctactttaa
     4261 aataaatgct cttatatgat tagatatttt tgcataatta aacgataaga aatcaaattt
     4321 aattttacat aaatagaata tatattttta tataataatt gaaaataaaa gaggatacct
     4381 cataatgata aaagaatcac tttgagatac cctcttacaa acaactaaat caataatttt
     4441 ctatctttca cactcttgat ttgcaactgt acaagaagtt ttacaagctg attgacaaga
     4501 agtttgacac tctccacatc caccttttgc agcactttgc tttaaagtag cttgagataa
     4561 agtttttaca tgtttatttt ccattttcaa cgcctccatt tctaattgtt tcctattgat
     4621 tatatcataa aactacttta atataaactc tatttaaagt tgacacccaa tacgcctcca
     4681 atgcctcctg ctgctgatat tagcaataac ttataaatca tccctacttc aaatacaaac
     4741 ttttcttgtg ctaaaaacac agtcaaaaaa atacatacta tgtacaaaag tcctactaaa
     4801 agcccataca taagtccttt ttctttcatg tgttttgaag tgtaaaaccc tcctatagct
     4861 gcagaaatag tagttataaa tgatgagacc atagttatat tatctccacc aatatctgta
     4921 aatgtcaaaa ataagttata cactaataaa acagccaaag ttattatata tgcatatcct
     4981 agacctttaa aaatataatt agattttccc ataaaaaaac ctcctctcaa attaatatat
     5041 attcgagaaa aggcttttaa attactaatt tagtcttctt ctatttcttc ttttttagat
     5101 tgaactgtac ctatggccca tttttcaaat ggaactttag ttctatttgg tcctaattct
     5161 aatattacaa cgtcatcttc aactttagct acattagcta ctattccacc tattgtaatg
     5221 accttatctc ctacacttag gctacttctc atttctttta attgtttgtc ttttttcttt
     5281 tgaggtctaa tcattaggaa ataaaagatt gcgattacta ctacccatag acctatactc
     5341 ataattattt gttgctgtgg cattaatttt tcactccttt gtaaattata ctcttttgta
     5401 aatcataata aatgtttata taacaattta ctttctctat ctttgagtac tattgaatat
     5461 tatatattaa aatgattata attaatagta caaaacctat atttcatatc catattttgc
     5521 aaaaaattca tttctaaaat caagtaatct atcttccatt atcgcttgtc ttatttgttt
     5581 cattaaattt aataaaaagt gaagattatg agtagttatt aatcttgcac ccaatatttc
     5641 atttgctttt ataaggtgtc ttatataagc tcttgaatag tttttacaag cataacaatc
     5701 acattcagga tcaagtggag taaagtcttc agcataagtt gcatttctaa ctactacttt
     5761 accttggcta gtcattgcag ttccatttct agctatacga gtaggtagga cacaatcaaa
     5821 catgtctact cctcttataa caccttccac taagtcatct ggactaccaa ctcccattag
     5881 gtatcttggt ttatcctttg gcataagtgg agttgtatgc tctagcacat catacataag
     5941 tggttttggt tctccaacac taagtccacc aatagcatat cctggtaaat caatattagt
     6001 tatttctttc gctgattgtt cccttaagtc tttatacatc ccaccttgta ttataccaaa
     6061 taaagcttgc ttgtcggtat tattatgggc atctttacat ctttttaacc atcttgttgt
     6121 tctttctaaa gaatttttta catattctct atctgatggg tatggtgcac actcatcaaa
     6181 cgccatcatt atgtctgaac ccaatgcatt ttgtatttcc atagcttttt ctggagttag
     6241 aaaatgtttt gaaccatcta agtgtgacct aaattctaca ccttcttctt ttatctttct
     6301 taaaggccct aggctaaata cttggaaccc tccactatct gtaagtattg gtttatccca
     6361 attcataaac ttatgaagac caccagctct ttttataagt tcatgacctg gtctcatata
     6421 taaatggtat gtgttactaa gtattatttg tgaaccaatc tcttttaatt cttctggtgt
     6481 catagatttt acagttgctt gagttccaac tggcatgaat attggtgttt caataattcc
     6541 atgtggagtg tgtaatcttc ctaaccttgc accactctgc ttacaagtct ttatcaattc
     6601 gtatcttact gcgtacataa agttctcctt aatcatattt atttctcatt atttcttaag
     6661 atatatttgt aataagctat tcatataatt tattgtctaa atagatttat cttcgtcttc
     6721 tttgttctgt tgttccttaa ttgcttcttc atcatgaata ctcattatat taagagcact
     6781 cttgtctttt gttactaaaa acttttttat agcaaatagc cctgctatag ctataactcc
     6841 tattaaaaca tctatcatac cttcattttt aggcagtagc aacatttttc tagctattgc
     6901 gtaaagtaat gcctcaataa atgctcctgg tatatgaaga gatagcatta ctacaagttc
     6961 aacacctatt actaaaagca atatttgtgc taagaaatca ttaagctgac tgtattgtac
     7021 tggattttga aaatcaacta tataagctcc ccacataagt cttagaatat ctatagttcc
     7081 taaaaatact gctattagaa ctactactgc taaaatacgt tcaaatataa aagcaatctt
     7141 taatataggg ttattctttt tttgtttttg taaactatgc atccattacc tccctacttt
     7201 ataatcatag catctccaaa actgaagaat ctatatcttt cttttactgc ctcattatat
     7261 gcatttaaaa cattatcctt tccacaaata gcacttacta acattattag tgtagactct
     7321 ggtaaatgaa aattagtaat aagtttatct aaaactttaa atttataacc tgggtatata
     7381 aatatttctg tccatccact agtttctttc atctttccat cctcattaca agctgattct
     7441 atagttctac aactagtagt accaacacat attacattgt ttccattttc ttttgctcta
     7501 tttattttgt cagctgcttc ttggctaacc atataatatt ctgaatgcat cttgtgactt
     7561 aaaacatcct ctacttttac tggtctaaaa gttcctaagc caacatgtag agttacaaag
     7621 gctatatcta cacctttttc ttttatttta tttaacaatt cttctgtaaa atgtaatcct
     7681 gctgtaggtg ctgctgctga accattatgc tttgaataaa cagtctggta tctttctttt
     7741 tcatctaatc tagcagtgat atatggaggt agtggcatat ttccaagttc atccaagatt
     7801 tcttcaaaaa ttccatcata atggaatttt ataattcttg aaccttcatc tgataaatct
     7861 acaacttctc caattagctt tccatttcca aaagaaaatt tagtccctac ttttgctctt
     7921 tttcctggtt ttactaaaga ctgccaagta tcttcctctg ttctttttaa taataaaaac
     7981 tcaattttac ctccagtttc aagcttctct cctattaatc tagctggtat aactctagta
     8041 ttgtttaata ctaaacaatc tcctggattt aaatattcta ttatatctct aaatacttta
     8101 tgctcaatat tacctgtctc tttatctaat accatcaatc ttgagctagc tctatcttct
     8161 ataggaactt gagctataag ttcctgtggt aaatcaaatt taaaatcact tgttttcaat
     8221 gttaaacttc ctctcttaaa atttctccag ctacaataat atcaaaaaaa caacttattt
     8281 tccacaatat taccataatc tatcaagaaa ttgctatttt taacagacac catatccaca
     8341 atatatggat atttttccac gatatacatg tcttatccac aatatataga tacaatacac
     8401 acaattttta tcatgtttat ccacagtatc tacagatata attaccattt tgtggatatg
     8461 tttgaatttt tagccatttt agaaatattt taatttaatg actattttat tttataaata
     8521 atcgtataat atatttttat ttttcgttag gatatggaat ttttaagtgt tcatatgcta
     8581 atggcatggc tactcttcct ctaggacctc tatttataaa tcctaattga agcaaatatg
     8641 gctcatatac atcttctatt gtatttctat cttctccgat agaagctgcc aatgtatcta
     8701 aacccactgg tcctcctcta aatttttcta ttatagtcat aagaagcttc tcatctacaa
     8761 aatcgagacc caaactatcg actcctaaaa gttccagagc atcttttgcc accttatcag
     8821 ttatttttcc atcagctcta acttgtgcaa aatctctaac tctttttagt aatctatttg
     8881 ctatccttgg agtccctctt gaacgttttg caagttctaa tgctccatta gactgtatct
     8941 ctgcatctaa gatgcttgaa gacctaagta ctatttttga aagttcatca actgtataat
     9001 agtccaattt acaaataaca ccaaatctat ctctaagtgg atttgtaagc ataccagctc
     9061 ttgtagtagc tccaataagt gtaaatttag gaaggtcaag tcttatgctt ctagcagatg
     9121 gccctttccc tattattata tctaggcaaa aatcctccat tgctggatat aaaacttctt
     9181 caacacttct attgattcta tgtatctcat ctataaataa aacatcattt tcatttaaat
     9241 tcgtaagtat ggctgccaaa tctccagctc tttctattgc aggtcctgac gtaattctta
     9301 aatttacccc catctcattt gctattatac tggctagtgt agtttttcca agacctggtg
     9361 gtccatataa aagcacatgg tctaactgct catttctcga tttagctgct tctataaata
     9421 tactaagttg ttctttggat ttttcttgac ccaaataatc ttctaaagtt tttggtctta
     9481 aactgttttc tatatctata tcttccatct tcattgtaga agttattatc ctattttcat
     9541 cttcaaaacc ttgcatttat acccctcctc tcgtactttt gaaaatctac tttatatatt
     9601 ttcaaattta cataaactcc ttaaatattg ttttaaaatc caaatattat aaaatccaaa
     9661 tactatttca aggatttact cattatatat gtaagtgctt tctttataat agcttctgta
     9721 ttcataccat cttttttaca tttttgaact gcctcttttg attccgacaa agtatagcct
     9781 aaagctacaa gtgcatctac agactcatct tgtgatatca aggtaggttt ttgtgataat
     9841 aacgttggtt caaactctat gttatttttg tctaccttat ccttaagctc taagacgatt
     9901 ctttctgctg tctttttacc aacaccagga gctttggata attttccaat gtcttcactt
     9961 aaaatatatg ctcctaactg tgctggtgat gcaaatgata gtattgaaag cgccacctta
    10021 ggtcctattt tagatacaga tgttagtaat tcaaacatct taagttcttc cctacttaca
    10081 aaaccacaaa gactcatatc atcttctctt acaattaatt tagtatatat ttttgtggct
    10141 tctcccactt gtaaattcat tattgtattg gatgatacat ttattttata tcctatccca
    10201 ttattttcaa caactatact gtctatataa atttcttcta ctgtaccttt tatataacta
    10261 tacatactta ccacctatat tctttagagt tttttcaagt ttgtttgaat gagcatggca
    10321 aatagccaca gctaaagcat ctgcaacatc atctggtttt ggaacttttt ttagacttaa
    10381 aaatgaagtt accatctgtt gaacttgtgc cttatctgct ctaccatatc caactacacc
    10441 ttgttttact tgaagtggag tgtattcata tacaggcttc ccattgtgag cacatgcaag
    10501 catagtaaca cctctagctt gtgcaactgt tatagctgtt tttacattct tgttaaagaa
    10561 taattcttcc attccaactt catctatatt gtaattcttt actattgtat caattccttt
    10621 atacacaagt tccaatcttc tcgatatatt catgtgggca ggtgttgtaa ctgctccata
    10681 atcgattgct ttaaacttgc tatttttgta ttcaattata ccatatccaa ctatggctat
    10741 acctgggtca atccccaata ttatcatttt ttaaaattcc ccctaaaaat aaaagaaata
    10801 ccaaaatgta tttctcataa aaacttatgt tctaaatcat tatatcataa ataatattaa
    10861 caaatcataa aatgctctat gtaaaatata aaatcaaata aaaaagttat atcaaagcaa
    10921 gattttacct caatataact tttatattta gtacaaataa attattgtat ttttatagga
    10981 attaaatgtg actacaatct taatactaat ttatttaaca ttgacttatt tagtattaac
    11041 ttacttaata ttaacttgca aagtcttcta atcttgaata agcttcttct tcagtatcca
    11101 taactacacc ttttttgatt tcatcttgaa ctgttttagg aagtgaatct actcttattt
    11161 ttgttttttc tactaatgtt ttacttccac tatcatcata tttatatagt gctatatttc
    11221 cattatcatt ttcaatagta tatttacctt ttatagtagc gttcattgct tgtacatctt
    11281 tattatcact atatttagat tctaccaata tgatttcatt tttatccata ctctttattt
    11341 ttttagttgg atattctttt ttaaaatatg atactatttc tgattttgtc ttatctaata
    11401 atgactctgg aactatccca gccattgtaa gtgttctctt atagttagtt tcattttcgc
    11461 cttcactttg aagccaaact tcacaatttt tatttaatcc aaaagcttct tttgactttt
    11521 cgtccatatt cgcactagca cttacaactt caccagtttg aactccatta ttttttaatc
    11581 ttgtccctat ataaactcca ctacttaata caaatacacc aactagtatt aaggcagata
    11641 ttttccaagg aaataattct tttttcttct tttcaaacat tgattacgcc tcctttttct
    11701 attattttct ccaagctgta agtttttata caatttaggt aaattttaga agaaaatata
    11761 tttatatttc aaattactct aagaatagat actttctaaa aggtagtttt ctcttaatag
    11821 ttatattctt gtaattatat ggacataatt tataataaat aatcgtttag gaggtaataa
    11881 ctttggaaag aataaactgt aatgtaatta actgttcaca taacaacagc catatatgtt
    11941 atgcagataa aatttttata aatggtgaaa aagctcacaa tgacagacat acttgttgta
    12001 gttcattttt agatgaatct atttatagta atttatctag caatgttaat aatagaaatt
    12061 gtgaggaatt agtttgtact gtaaaaaatt gtaaatacaa caaagatggt agcttatgta
    12121 cacttgataa tatattggtt gctcctgaaa ctgatagagt aaacctttat attgaaacat
    12181 gttgctctag tttcgaatgt aaatagtcat agtataaata taagggtgtc aaatgtaatt
    12241 aaactaacat agtgtagagt atctacaact attagtttga ttatacttga cacccttatt
    12301 tattttaaat aaaatttcat tattataacc atgtttataa tgttctaact gtaattaaat
    12361 ttgataaatt tctataaatt ggtataatca atatgtaaat tgaatttagc aaattaatca
    12421 taaaaataaa atatcgagta tatagtgtta tactaactag aaatgaggtg cttatgagta
    12481 cattttatat tcaatttctt tattttgtaa tttatagctt tataggatgg tgttgtgaaa
    12541 ctacatattg ttcagtttta caaaaacaat ttgtaaatag aggtttttta aatggtccat
    12601 tttgccctat atatggattt ggagcattag caatagttgc taccttgact ccttttgtac
    12661 aaaatattcc tttgctgttt ttgtttagta taattataac tagcataatg gagtatttta
    12721 cgagctttat tttagaaaaa atatttaata tgacttggtg ggattattct aaacataagt
    12781 ttaatattca tggaagggtt tgtctggaaa actcacttat gtttggtgta ttatcattaa
    12841 ttgtaatgct tatagtacat cctattgtgg ttgattttat taactctatc tctaaaaatg
    12901 tgctatttat atttgctata tctatagaaa tttattttgt tttagattta gtgattacag
    12961 tccatacaat tttacaatta aatggtaagt taaaacaaat caatcttata attaaggaat
    13021 taaaagataa gaaagaatac tacaaactta ttacacaaga aactatagaa aacaaacttg
    13081 aatctttggt tgaaaataga ctggatactt tggaagatag gtttgaaata cttaaggaaa
    13141 aagaaaacta tcgctatgct aaaaatcgta ttgatgagct aaaaaataaa cttaatactt
    13201 tactgtctaa ccacaaatta cttcatagac gtataatcaa agcattcccc aacataagct
    13261 ctaataagca tacagatatt ttaaataaaa tcaaagaaaa tattaaatca attaaaaaag
    13321 ataaataata aaataaacac ataagttaaa taataaaaat actaatacat aagattaagg
    13381 tttagaatat tttttgtaaa atgctctaaa ccttaattaa tatactatta tttttaatct
    13441 taatttataa ttttagttta ttttactttt aacacagtaa atttaagcgt ttaaacttca
    13501 atacactaat atactacccc atcaatatct caactgattc tctaagtgtg ctaatctctc
    13561 ccacatttcc agggaaaatt atatatggca tattaggaaa tttgctttct ttgcctgtca
    13621 tccatactgg tataccaggt tttatctgtc ccattactgt agcttttttt actcttaatg
    13681 ctttagtacc aacatcacta gaagtaattc cacccttagc tataataaaa tttggtctta
    13741 cattaagcat accaattata ctggtaactg catctgatat ttctacagaa atcataagct
    13801 gtttatcttt atcattcgta tccaagtcaa aacgctctcg tctagtataa acagcaacag
    13861 ttttaccact gcttattttt tcctctacaa cttttataac tctttttacc tcatttttta
    13921 gaccattttc ctgaagaact aaatgttgat taaattctat aaattctatt ggatatttac
    13981 aatttttaag ttcttctaac tgttgggtag tcttattcac atgtgaacca acaagtataa
    14041 ttcctccatt ggtattacct tttgatacta actcatcctt agtaagcatt tccttatcac
    14101 tcactccgcc aagtactttt gttatggcag cagcgcttct aaacataaat tccttaccac
    14161 tatttactgc tcgtataaac gcaattgtaa atacctttac atctacataa tcggttgcat
    14221 ttacaataat tttattgaat ccttcagctt ttttaagttt ttctgttata gcttcaatat
    14281 ttagctctct aagttcttta gaagaaatat atatcatatc actagatttg tactttccat
    14341 gtgtcttttc ttcacaccac tcacctatat cagatgattt atatccaaaa gatttatcct
    14401 ttgcaaattc agtcattcct gctggtacaa gtatttctcc ttctttaaca taatgtacat
    14461 tatctatagt aaacctacca ccttctttaa aaaatggcat tattatttca ccctgaaata
    14521 acttccccga taatctctct acttcgcttt ttaataaatt agtttcaaca ggataatgtc
    14581 ctctcatagt agaatcacta cgacttatga ttataaaatc cttattaact ttctttgata
    14641 catccacaat attctttgaa atttctttat gtgcttttgt agtttgagca acagtaaatc
    14701 cccttgaatt agtaagtata aaaaacatac tatttttctc attaaaacct tgttccatac
    14761 tatccttatc ccaatcagta taaacagaaa tatcatgaac tgtttgtaca cctgttgggt
    14821 catcatctaa tacaacaatt tttctatcta aatgcttaag ctcatctgca agaagttcat
    14881 ttaatctgtc ctcatctact tgtttaaaag tattaagtat atctatgcta attggtttta
    14941 cttctctcat ttaaaacgcc cctttatgta atttgtatag tctaaatgta atttatataa
    15001 tataaacaat agtttgttat ttatagacct ggaagtggta taattccatt tataacacta
    15061 agcaataaaa ccattataaa tgctacaact ccagcaatgg ttcctccaat tgtccaagag
    15121 tttaaagtat ctttaactga taatccacta aatcttgaaa gtacccagaa tccagaatca
    15181 tttggaaggg agaaaccaac tcctccagca catatagcaa gccctactaa aactggtgac
    15241 attccagttg ccaaaattgt aggtcctaaa attgatgatg ttgttactaa ggctacagta
    15301 gcagaacctt gagaaattct aagcaaagca cttaataaga atccaagcac tacaactgat
    15361 atactaagac cagacatagt atcaactaag aagttaccta taccacttgc atttataaca
    15421 ctgccaaacg caccacctga acctgttatc aataatatta gccctgctga atcagcagct
    15481 tcaataacta catctcccat aggtttattt atgtatttct ttaaaaatcc tattgccacc
    15541 aatattccaa gaagtattgc tatgttttta tctcctataa atgcaagtac tccactcatt
    15601 gtagaacctt tttctaagaa catactaaat acatttgata taagtataag aagtattggg
    15661 aacaataaag aaaacataga aattccaaaa cctggtactt tagaagaatc atcatcttca
    15721 atttttatgc tatcttttcc ctgctctaaa tttttttctc tatcattctc atcaatagca
    15781 taagctggat atttttcaaa acgttttcca taaatccatc cacctataag agctgctgga
    15841 aaagcaacaa ttatagaata aagtataaaa ctacctacat ttgcatttac atttgctgca
    15901 actgctaaag gtcctggtgt aggtattaca agtgcatgac ctactatagt cccaactcct
    15961 aaggcacata caaaaaccat tagagatttc ttagttactc tcgaaacata cttaattata
    16021 ggcatcatta taacaaaagc tgcatccata aaaactggaa ttgaaattaa aaaacctgct
    16081 gtagttactg ctaaagcact gtttttttct ccagtcttag ctaacaaccc ctttgcaata
    16141 gattctgttg ctcttgattc tgaaagaata tttccaaata ttattccaag tccaattaca
    16201 atacctatac tacctaatgt atttccaaat ccagtcgata ttgtggttga tatttcattt
    16261 ataggcattc taaccataaa gcctgtaatt atagatgtta tcagtaatgc caaaaacgga
    16321 tttactttaa atttaataat cgatataagt aaaattccta tagatataac aaatgctatc
    16381 aaaagtccat atcctgtaat cataatcttt acccctttat cattctactt tattatttat
    16441 caattttatt tttcttttac tatgataact taacctcgct gtatttatat aatctaatcc
    16501 taataatatg tatttaatta tattgatata tttaaatatt aattattgtg tttttttatt
    16561 tcaacacctg ccaacttttc aaaatactgt gctattccac tatggtcatc ttccaaatgt
    16621 ccatgtactt ttaatgtctg cataatttct aataattgac ttgtcatagg tagcggtaca
    16681 tctaaattgt gtgctgtttg cattacattc ttaatatctt tcaaattaat agatattttt
    16741 ccacctggtt taaaatcacg attcataatc attggtatct tcgcatccaa tattgtacta
    16801 ccagctaggc ctcctcttat tgccttatat actttttctg ggtctgcacc tgcttttgct
    16861 gcaagtacaa atgcctcaga aactgctgct atcgtcaaat taactattac ttggtttgta
    16921 agttttgtaa cacttccact accattatct ccaattaaaa tagatgagct tcccattata
    16981 ttaaaaaatg gctctacttt cttataaatt tcttccttac caccagccat aaaagcaagt
    17041 gtaccatcaa tcgcttttgg ctccccccca cttactggtg agtctataaa ttctaagccc
    17101 atatctttta atttatttgc acacaatatg gattctgtag gagtaactga actcatatcg
    17161 actactatac ttccttcttt taaagttttt gccaatccat ccatcccaaa caatatatcc
    17221 tgcacaatag ttccatttgg aaggattgta aatacaatat cacattcttg acccatttct
    17281 aaaacacttg cgtatttggc tccacatgat ataagttcat ccacagcaga tttattaata
    17341 tcatacacca aaagattaca tccatccttt aataaatttt ttgccattgg ctttcccatt
    17401 attcctaatc caataaatcc taatttcatt ttatacccct ccatatcttc acatttttga
    17461 aaacgttttt tatgttttag agtatactac ataccagtat accggtcaat ataaaatata
    17521 aaagtattta ttttaacaat aaatagtaat ttttaaagtc atttattata tttagtcatc
    17581 ctatataagt tttaatacat actattgttt ttaaatataa tatactactt ttacagtttt
    17641 gtattttaac tgatttcaat taattttaat taatctgcct ttaatgttaa tcatacttca
    17701 cacttcaata atttttatat tttttaatct tatctgcaat ttaaattgca aaagattgac
    17761 cttattttca ctatgttgta tgcttaaaat tatataagtt tttgtatttt tatattgttt
    17821 aggggggtat tattaagtat ggctacattt aaaagattac aagaacaagc atatgactac
    17881 ttaaaagaat tgatactatc tggagaaatg atagaaaatg aaatatattc tgaaacaaaa
    17941 cttgctagtg aaataggcat ctctagaaca cctataagag atgctcttca aagacttagt
    18001 caagatggat ttatagatat aatcccaagc aaaggattta gaatccatca aattacagca
    18061 aatgaaattg tagagatatt ccaaatacgc tctgcaatag aagggttttg tactttttta
    18121 attacaagtc aatacaaaga atctagagca gtagaaacta taagtaaatt aaaatatctt
    18181 ttagataaac aaaaagatat tttattaggt gataaaaatt taaactcatt tgcagaatac
    18241 gatacattat ttcacacaac tatagtttca tatgctcaaa atactgaatt tgacaaaatg
    18301 tttaacaatt atatgtatag aataaaaaaa ttagctctcg attcattatc acatgaagga
    18361 aggcttgaaa caacattaaa agaacacaca gatattttta ataatattgc aaatggatgt
    18421 attgaagatg tttacaaaac tactctcatc catatggaaa ctcctaaata cattaattta
    18481 gaagattttt gtaataataa gagattttag tattatactt tcatttatta aaaatatatc
    18541 tatctcaaat taatttccta atttataaaa aatattctat aattatattg taactaatac
    18601 tattctaagg agtgattttt ttgaacgaaa atgttgtaac taatgaaact attgacaaag
    18661 attatgctat tgaagaagtt cgtatggcat gcaaacattt tggtgactta tatttttatt
    18721 tttccaaagt gttatttgaa gagtttggtg aagataaaac tagtgaaata ctaagaaaag
    18781 ttttatttga aaggtctgaa gaaagagcta ttgctatgag agaaagagct cttgaaaatg
    18841 gagatgaatt aattgcagac aatattatta gcacaactga tgttccattt ctaggatggg
    18901 ttcctgaatt taaagagtta cattgccctt atggagcttc ctggctttta agatttgagg
    18961 aaaacccttg gtttaaaaaa ttcgcttctc tttactgtga tgttacagat actactgtag
    19021 ctgaagtatt tacaggagat acgtcccata aaataacaaa aaacattcta tggggagata
    19081 aaagttgtga aagaatatat ttccatgatg acaaggtatc tgaaggtaaa tatacttatg
    19141 gaaataaaaa ctgtaaataa ataatttaaa ttttctatat tcatatacta tattttgtac
    19201 tttttcatat aaatattata actagtcttt tattttactt ttgtttaacc taaagataat
    19261 ttacttttaa tctatatgaa ttatcatata aataatcaga aagttatctt tataaattat
    19321 agttttagat ttataattta taaaatattt atgttctttg taaaattttt tagaagcttc
    19381 taatgttatg ctataaaact atcttgagaa gggctgattg aatgtttaat aaaatatatg
    19441 aaaagaaaga atttatagtt tttcaagtta aaaaaggtta tgtagtttat aatactagaa
    19501 agagttttga agaaggtcat acacatttaa agcattttga agcagcaaag acagctattg
    19561 atttagcaat aaataaaaag attcctagaa gcaaagatgg atattatctg actagtttaa
    19621 ttcgcataag tgatgatggt tattacattg ataagttaag cgaattgtta tatgttagag
    19681 aacaaaaagg taaaaaagaa aagtactgta attctggtta tcagatgtaa caagactagt
    19741 tgtgaattat aagtaccaat cataaatacc tttagtctta aaatcaaaga gtatcagtaa
    19801 atctataaaa aaacaactta ctgatactct ttttaattat atgattaata tttgaatttg
    19861 atacaaaatt ttatacaaaa gtttatgtta tctattctga ttctttgtct gcaaattggc
    19921 tattataaag cttctcataa aatccaccct tttccattaa ttcatcatga ttcccctgct
    19981 ctataatact tccattattc ataactaaaa tcaagtcagc attgcgaatt gtagaaagtc
    20041 tatgtgctat aacaaaacta gttctaccat tcataagatt tctcattgct ttttgaagca
    20101 taagttccag cctagtatca acagaactcg tagcttcatc aagtatcaat attgaagggt
    20161 ctgatataaa agctctagct atggttaaaa gctgtttttc ccctagagat atattagatg
    20221 cttcttcatt taagaacata ttgtatccat ctggaagagt ggttataaag tgatgaacat
    20281 ttgctacttt tgctgcttgt ataatttctt ctttagtagc tccaaatcta ccatattcta
    20341 tattttcaaa aatggttcca ttaaataacc atgtatcttg aagcaccata ccaaacattg
    20401 aacgcaaatc tttacgtttc atatctctta tatctactcc atcaatttta atagcacctt
    20461 tctttacatc ataaaacctc atcaataagt ttattaatgt tgttttacct gctccagtag
    20521 gtccaacaat agctaccatc tgaccacttt ttacttctgc atttaaatct tctattaaag
    20581 ttgaattttc tccatatcca aaattaacat gctcaaatgt aacatttcct tttacatttt
    20641 ctatcttaac tggattttca acatcaggta tttcctcttc ttcgtctaaa atttcaaata
    20701 cacgttctat agctgcaaaa gaagattgta ttactgtaga taactgagtc atttgtgaaa
    20761 gtggctgatt tatctgccat atataacgca caaatgcttg taaatttcct actgttatcc
    20821 ctccacttac tgcatatata gaaccgacaa ctgccacagc tgcaattcca aagtaagtta
    20881 ctaatgaaac cataggattc atcatacttg atataaattg tgccttaaat ccattttcac
    20941 aaagttcttg atttactttt ttaaattctt ttatagaatc ttcttcttta ccatatagtt
    21001 ttatttcatt aaatccagta tacatttctt gtacttttcc atttaatttt ccaagagcat
    21061 tttgttgcaa tgaaaatcta ctttgagact tttttactac aaatttagat acaaaataac
    21121 taattggaat tataaaaaga gctataagag ccatatatat attaattgta aacatcattg
    21181 aaagtgccaa aattatgact aagattgagt ttacaatttg cataaaactc tgttgcaatg
    21241 catttgatat tgtatctaca tcatttgata tacgacttaa tacatctcca aaactattac
    21301 tatcaaaata actaataggt aatcttctta ttttattttc gacttcattt cttaaatctc
    21361 tcattgtgtt ttgaatagca ttcgtaagta gaaaacttga agtatacgta aaaattgcat
    21421 tggcaaaata tatacatgct aaaatcacca atatttttgt tacataatca aaatttacgg
    21481 aagcccctgg tactcctttt gcgatactaa ttacatcttt agtcaattgt gttattatca
    21541 atccttcagt tttaggtgca agtgcattca tagtagctgc tgaaattata catataatag
    21601 ctataataaa ggaaaattta tatttcttta caaatggaag aagtctacca attgttttct
    21661 taaaaccttt agactttttc attattctaa ttcctccttt tttaactgag atgttgcaat
    21721 ttcatagtat atttcacagt tttttaataa ttctttatga gttcccattc ctacaacttg
    21781 tccttcattg agtactataa tcttatcagc atcaataata gaactaattc tctgggcaac
    21841 aatcaataca attgcatctt ttgtttcctt cttcaattta gcacgaagta ttgcatcagt
    21901 tttaaagtca agtgcagaaa aactatcatc aaaaatgtat atttcaggtc ttcttataat
    21961 agcccttgca atagaaagtc tttgtttttg acctcctgat acatttgctc caccttcact
    22021 aatcaattca tcaaactttc taggtttttt tgatataaac tcatatgctt gtgcaacttt
    22081 tgcggaatat tctaattctg actctcctgc cttatgtttc ccaaatctaa tattatttgc
    22141 tatgctacca gtaaaaagca gtgatttttg aggtatgaat cctatctttt ttcttaaagc
    22201 ttttaaatca tattctctta tatctactcc atttatctta atgctacctt ctgttacatc
    22261 ataaaatcta ggtatcaagt taattagagt acttttccca ctaccagtac ttcctataaa
    22321 agcgactgtt tcacctgttt ttgcagtaaa tgaaatatcc ttaagtacag aagcttctcc
    22381 atctggatag gtaaaagtta cattatcaaa ttctatgata cccttacttt cagtatcctt
    22441 aattccattt tcaggatttt ttatcaatgg ttcttcattt aaaagttctt ttattctatt
    22501 tgcagatacc tctgctcttg gatacataat aaataccatt gaaaaaagca taattgaaaa
    22561 catggcatgg aaaagatatt ccaaaaatgc aaccaactgt ccaacttgaa gctctccaat
    22621 atttatcttc tcacttgaaa tccaaaatac agccaaaaca gctatattta atagtaaaaa
    22681 gaatgctggt tgagtaattg acataagctt aaatagtttc ttagaaacat tagcataata
    22741 tgtatttgtt ttttcaaatc gctctgtttc ataatcatca tttccaaaag ctctaattac
    22801 tcttattcca gttaaatttt ctctcgatat aaggtttaat ttatctagtc ctttttgttg
    22861 ttttgaagat attgcctgag atacttttgc tattattgct actccaataa ttataaaagg
    22921 tactgatata gccaatacta tagaaagttc cacacttgtt ctaattgtca ttattatact
    22981 tataatgaac ataactggag ttaataaggc agtccttagt agtatattaa caaattgttg
    23041 aatttgaaat gcatcattcg ttgttcttgt aatcattgaa gaaattccaa atttattgta
    23101 ttcagtatgt gaaaattctt gtgatttctc aaatatgtca tttcttatat ctctggttac
    23161 acttgttgat accttagcag aacaataacc caacaatata ctacctacaa cccctataat
    23221 agaaataata acaatcacta ttcccatttg ttttatgtaa gctatattct gatttgcaat
    23281 accattgtca attattttag ctattatagt tggaatcccc aactcgacta atgcaaaact
    23341 aaatatagcc agtatgttta atactattaa taacttataa ttctttaaat aacttaaaat
    23401 taatttcata tttttctcct ttcttaattt ttgagatagt gtaatcatgt aataatacta
    23461 aatttataaa tgcttaattt tataaaaaaa ggagaaaaga gttaacgcac tctcttctcc
    23521 agcatattct ttttaataca ccctccgaca agtcgcttat atgttaacat atttgacaag
    23581 taatgtcaat tcatatagcc aaaagtcttt taaatgcttc atttcataac attgtaacaa
    23641 attggcatgt aatttatttt tgttttttac tgtattccaa ttttacaagt tctccaatat
    23701 tactagcttt cttaaaattc aaattagtct tgtctatacc agacttaaat agtgaaatcc
    23761 ctctccccaa tattattggc aatatatata tataataatc atcaattaag ttatctttca
    23821 taaataattt tactatatcg cctccaccaa ctatccaaat atctttttta tccttctctt
    23881 ttctaatttg ctcaattaat tttttaggtt ctaaattagt atactttaca ttctcagttg
    23941 tcccattaat tgtatttgag tatatatagc attccttacc cttatagtac cattcatttg
    24001 ggcttaattc atttgcaatc tgtacatatg tggaatttcc cataatgata gtatcaattg
    24061 tatcgtaaaa agtattataa tcatcttcct gctcattctt aaattctgaa gatatctcgt
    24121 ctaaaaaact tacactgcca ttctcttcag ctatataacc atctaaactt gtggcaatat
    24181 aaagtactac ttttctcatg tttactacct ccaacattta tagtgtgatt attctatgta
    24241 aacatcactt ttttactcat tcaataatac cctattaata aatcctcaaa ctaatttaaa
    24301 taaactttgc ataaaattaa aaatatatta tataaataat ttaaaaccac aataacttat
    24361 tgaaaattct aattattaca aataaatatt gctctctgtt aacgctagtt ttataatata
    24421 attataagct attaatatta taaagctgat attactaata taataattat aatacttata
    24481 gttaatttac ttttgttgaa aggtggtaaa taacatgaaa atttcagaag tcgctactcc
    24541 aaattttttg ctagatttag accagttaga aaagaatata gataaaattc aacaaatttg
    24601 tacaaataat aataaacaac tttggcctat gcttaagaca cataaaagta cttacatagc
    24661 gagacttcaa aaaaatgcag gtgctagtgg ttttctagtt ggaacacttg atgaaggtga
    24721 agctctgata aaagcaggtt ttgaagatat tatgttggct tatccttaca tgggagaagt
    24781 aaatataaat agaattgtga ctatggcatc aaaaataaat ttaatctgtg ctacagataa
    24841 tatagaatgt gctaaggctt atagtgaagc tttttctaaa tcaaaaatag agtgcaagct
    24901 acttattatt gtagattgtg gcttacaccg ttttggggtt gaaccagaaa aagtagttga
    24961 acttgctact gaaatttcta agctagaaaa catcaagatt gttggtataa gttcgcatcc
    25021 agggcaagtg tatggttgta gttctccaga agatgttcca gatgtttgtg ttcaagaaga
    25081 ttcttctatg gagaaagcat acaaagctct aactgataat ggatttaata tagaaattgt
    25141 cgcttctggt agtactccaa cagttgaagc tgaagctgct tctaaaacta taactgctgt
    25201 aagacctgga aactatgtat actatgatgc tatacagata ggtttaggtt gtgctactga
    25261 agatatgtgt gctcttactg ttgtgtgtac tgtaatctca aaaaatagca gtggatatta
    25321 tttaattgat tgtggaagta agtgccttgg acttgataaa ggtgcacatg gaaatagtag
    25381 tattgttggt tatggtaggg tatgtggaca tccagaactt actattgatt cactttcaga
    25441 agaagttgga aaaattaaag taaatggtga aactgatata aaaattggtg atagaataag
    25501 aattatacct aatcattctt gttccactgc aaacttgacg agtaatttat taggttttag
    25561 aggagataca atagaaaaag tcatagaagt agatattcgt gaaaattcaa aacaaatcat
    25621 cctttaaaaa tatatttatt ttgatattaa catcatgaaa gtatattttt cttaaaatta
    25681 ttgttaataa ctaatgttaa tgttggataa ataaaaaaca taaattctag aaatataaat
    25741 ttaaaaaaag aggctgtctc aaaattggat atgtccctgt caagtagaca gacttaaaaa
    25801 aggctatctt tatgcggaat gagttcgata ttcaatcgga ctcattcc
//
LOCUS       DACTZW010000059        25547 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.059, whole genome shotgun sequence.
ACCESSION   DACTZW010000059 DACTZW010000000
VERSION     DACTZW010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25547)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25547)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25547
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.059"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(170..949)
                     /gene="hisJ"
                     /locus_tag="JAM15_12640"
     CDS             complement(170..949)
                     /gene="hisJ"
                     /locus_tag="JAM15_12640"
                     /EC_number="3.1.3.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ"
                     /protein_id="HAT6799100.1"
                     /translation="MKDGHIHSPYCPHGSKDDFEKYVQRAMDVGITEMTFTEHFPYAN
                     EFRDPAPENDSCMSIEDLPKYFNDVKKLKEKYEGKIKINVGSEVDFIEGYEEGIKENL
                     NKYGKELEDSLLSVHIIKIDDDYYCVDYSVEEFQNLIDKLGSIEAVYNKYYETLIKAV
                     NSDLGIHKPKRIGHLNLVRKFNQVFPYDYKGNTILEELIKLIKEKGYELDYNVSGNRK
                     EYCKEPYIDGYLLELVKKYDIPLVLGSDSHCAEEINKYDII"
     gene            complement(1489..1839)
                     /locus_tag="JAM15_12645"
     CDS             complement(1489..1839)
                     /locus_tag="JAM15_12645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter"
                     /protein_id="HAT6799101.1"
                     /translation="MIFDKEIVRYHHGHHDHDHCHEHTHGDICHEHPHDHAHDHDHEH
                     SHEESSESKDEKTLKILLVHWINHNETHEEGFREWVEKARAIGKEETAKSIEKAIEYM
                     EEANKMLLEAKKHM"
     gene            complement(1855..2271)
                     /locus_tag="JAM15_12650"
     CDS             complement(1855..2271)
                     /locus_tag="JAM15_12650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3842 family protein"
                     /protein_id="HAT6799102.1"
                     /translation="MIIAVIDGMGGGIGAQIVSSLREELPTYVEIYALGTNSIATSSM
                     MKAHANKGATGENAIVVSAKKANIIVAPISVIIPNSMMGEVTCNISEAIADSEALKIL
                     LPIMPENVELVGLEGKPLALLVKDSVNLIKKEFNIK"
     gene            complement(2290..2481)
                     /locus_tag="JAM15_12655"
     CDS             complement(2290..2481)
                     /locus_tag="JAM15_12655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CooT family nickel-binding protein"
                     /protein_id="HAT6799103.1"
                     /translation="MCESSAFICKSNNELEKVMENVVNIDPCDGKIYLTDLLGEQKII
                     DGIIKEIRLMDHKIIIQEN"
     gene            complement(2632..3447)
                     /locus_tag="JAM15_12660"
     CDS             complement(2632..3447)
                     /locus_tag="JAM15_12660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HAT6799104.1"
                     /translation="MNQWRVIHNKSYEGAMNMAIDEAIFTAYKKGHNKPTLRFYTWEP
                     ACLSIGYFQKLEDEIDLDKCRCMNIDYTRRITGGRAVLHDNELTYSIIIGEDNPLIDK
                     SINLSYRYISEGLVKGLNLSGIGTDNLNRGERISRENLSAACFNAHASYEVTINNKKV
                     IGSAQSRKDGVLLQHGSIILDFDVEKLFKLIKTKTPELKERAMKFTAKKASGIENEIG
                     RKIDIDILQKNIVKGLAEQFNVEFVEGDLTDYEKQLVKELYEKYKNEEYNKKR"
     gene            complement(3494..4432)
                     /locus_tag="JAM15_12665"
     CDS             complement(3494..4432)
                     /locus_tag="JAM15_12665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HAT6799105.1"
                     /translation="MIRLSVGTAIELGILNKKSDIPPTTAYIMIGEKCINKCSFCSQS
                     IESSTRKDKLSRVIWPEFSKEEILDALKAYKGKNIKRICIQSMASEEAHNSVLDFINY
                     ISGKIDMPISLSAKLENDEQIKKFFSAGVDKIGIAIDAANKELYEKIKGNNYDEKLKF
                     ITEMSKSYPNKISTHIIVGMGESHEDIYNLYIYLKENDVTISLFAFTPVRGTKMEKIN
                     QPSIESYRRVQLMSYMINKGYPKEYFKFKNGYLNSIKLDNDILKDINKGYPFEIRGCK
                     DCNRPYYNERPGSTIYNYSRPLNQSEIDLAIREINL"
     gene            complement(4429..5301)
                     /locus_tag="JAM15_12670"
     CDS             complement(4429..5301)
                     /locus_tag="JAM15_12670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HAT6799106.1"
                     /translation="MNKNLSEKMKIAFDIKLKNFGNKIEFAYPNQTLALSTTSNQCSL
                     KCAHCNGHYLNNMVPIEEYEEKVQSRNITSFLLSGGCSYEGDVPINTHINTIKNLKEK
                     GYRLNAHLGLMDKDSIVELCKYLDIVSFDLVFDDETIREVYKMKKSKEDYIEVYNTIQ
                     EHTEVAPHICIGLKGGQIKGEYEIIEYLQKNPPNKLTFIVLIPTKGTEYENVEPPELE
                     GVADILCEARINLPDTEINLGCMRPRGVYRKELDQLSIMCGVNRIVLPSRSAKNKAIE
                     MNMTINECKECCVL"
     gene            complement(5326..7254)
                     /locus_tag="JAM15_12675"
     CDS             complement(5326..7254)
                     /locus_tag="JAM15_12675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4445 domain-containing protein"
                     /protein_id="HAT6799107.1"
                     /translation="MIKVSFTPNNKEVYCNEGDILLEVARNADIFIDAPCNGNVSCGK
                     CKVKLLNGKVDTEKTRHITDDEWEQGYILACCTKVISDIEIEVPSKVSSSMHGMKIEG
                     SNKKEDREIFERAKKIIEEHNLQFKTNIKKKYIEMEEPNLDDNISDVDRLERYVRNNL
                     GYNEIDFRLDILRKMPTVFRKSDFKVTITYVQKQKKLTIINIEQGNKENSLYGVAIDI
                     GTTSVVVCLVDLYSKEVVDKASSGNAQIKYGADVINRIIYSTKKNGLEILHKAIVEET
                     INPLLKTIYERNGIDKEDVVTLVAAGNTTMTSLFLGVYTDFLRQEPYIPPFLKSPKLM
                     GENVGLFVNDSAYVYLAPSVASYVGGDITAGVLSAGIWSSEENVLFIDLGTNGEIVFG
                     NKDYMMSCACSAGPAFEGGGISCGMRASAGAIEKVIIDKETLEPTLKIIDECAPVGIC
                     GSGIIDLICQMITKGVIDRRGKIYRDLDNKRVRFNEHEIGEYVLAFKEEFDLENDIVV
                     NEVDIDNFIRAKGAIYSGAYTLVDSLGMDFSILDRVYIAGGIGNNLDIENSIIIGLLP
                     DIDREKFTYIGNSSLVGSYLALISKDAKNKLEEIGNQITYVELSVYPSYMDEFISACF
                     LPHTNIEQFPTAKKLLEE"
     gene            complement(7366..7743)
                     /gene="gcvH"
                     /locus_tag="JAM15_12680"
     CDS             complement(7366..7743)
                     /gene="gcvH"
                     /locus_tag="JAM15_12680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HAT6799108.1"
                     /translation="MKLLPELKYSKDHEWVKVIDGDVVYIGITDYAQDQLGEILFVET
                     PEVEDTVTKGVDFGVVESSKVASDLISPVNGEVLEVNEKLEDEPECINEDPYENWILK
                     VKLADVAELDTLLSDKEYEAGLE"
     gene            complement(7830..9956)
                     /gene="cdhC"
                     /locus_tag="JAM15_12685"
     CDS             complement(7830..9956)
                     /gene="cdhC"
                     /locus_tag="JAM15_12685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013240359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CO dehydrogenase/CO-methylating acetyl-CoA
                     synthase complex subunit beta"
                     /protein_id="HAT6799109.1"
                     /translation="MNLYNIIFTGSEQALGAAQAMLAEAIEKNGKEHKVAFPDTAYSL
                     PCIYAATGQKMNTLGDLEGALEVVKSLINRTHLLEHAFNAGLATALAAEVIEALKYST
                     MDAPYSEPCAGHITDPIIRSLGVPLVTGDIPGVAVVLGECPDAESAAKVIKDYQSKGL
                     LTFLVGKVIDQAIEAGVKMGLELRVIPLGYDVTSVIHVVSVAVRAALIFGGLTPGDLN
                     GLLEYTANRVPAFVNAFGPLSELVVSAGAGAIALGFPVITDQTVLEVPMNLLTQKDYD
                     KIVATSLEARGIKIKVTEIPIPVSFAAAFEGERIRKSDMFAEFGGNRTEAWELVVKKE
                     ATEVEDHKIEIIGPNIDEVDADGVLRLPLAVIVKIAGKNMQEDFEPVLERRFHYFLNY
                     IEGVMHVGQRDMAWVRISKDAFDKGFRLEHIGEVLYAKMLDEFESVVDKCEITIITDA
                     EKVSELKGEAIAKYNARDERLASLVDESVDTFYSCNLCQSFAPAHVCVVTPERLGLCG
                     AVSWLDAKATKELDPTGPCQPIEKGECLDDRTGVWNSVNETVNQISQGAVESVTLYSI
                     LEDPMTSCGCFECICGIMPEANGFVVVNREFASVTPVGMTFGELASMTGGGVQTPGFM
                     GHGRHFISSKKFAYAEGGPERIVWMPKELKDYVADKLNATVKEMTGIENFCDMVCDET
                     IADDSEGVLAFLEEKGHPALAMESVM"
     gene            complement(10013..10819)
                     /locus_tag="JAM15_12690"
     CDS             complement(10013..10819)
                     /locus_tag="JAM15_12690"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HAT6799110.1"
                     /translation="MEKFMIIGERIHCISPSIRKALAERDPAPILKRAKEQLEAGAHY
                     IDFNIGPAERDGEEIMTWGIKLLQSEFNNVPIALDTANKKAIEAGLKVYDRTNAKPII
                     NSADAGSRFDLIDIAAEYEAMVIGLCAKEGIPRDNDERMAYCQEILEKGLMLGMEPTD
                     ILFDPLCLVIKGMQEKQVEVLEAIKMMTEMGLLTTGGLSNVSNGCPKHVRPVLDSAFL
                     AMAMANGFSSAIMNPCDPELMKTVKSCDIINGASLYADSFLELNEGGFAF"
     gene            complement(10869..12236)
                     /locus_tag="JAM15_12695"
     CDS             complement(10869..12236)
                     /locus_tag="JAM15_12695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit gamma"
                     /protein_id="HAT6799111.1"
                     /translation="MALKALDIFKLTPKKNCKDCGFPTCMAFSMKVASGAVEVGKCPH
                     MSDDAIAKLSEATAPLMKALKVGAGASEYELGGETVLFRHEKTLVSRNRYAVSFCTCM
                     SDEAVDAKIANMKKVDYVRIGEQMKVEMAVLEYCGDKDAYLKLIDKIKGSGLEVAYIL
                     ACDDAQVVKEAVEVLKDARPMVYGATKENYKDMIEVVKGASLPLGVKAGSLEELYETV
                     ELIQAAGYKELVLDVTGENIKDTYTNAIQVRRIALKEQDRTFGYPSIVFANRLSNSNP
                     MMEVALSSIFTIKYGSIIVIDDISYAKALPLFALRQNIYTDPQRPMRVEPKIYPINNP
                     DENSPVLVTVDFALTYFIVAGDIERSKVPVWLVIPDAGGYSVLTSWAAGKFGGNSISA
                     FIKESKVEEVTNCKDLIIPGKVAVLKGDIEDNLPGWNVVIGPEESMELPKFLKGYQEK
                     ACQTN"
     gene            complement(12267..13211)
                     /locus_tag="JAM15_12700"
     CDS             complement(12267..13211)
                     /locus_tag="JAM15_12700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit delta"
                     /protein_id="HAT6799112.1"
                     /translation="MAFKMSTQKYSGKISEVEVGIGEKAIKLGGENVLPFYSFDGEVG
                     NSPKIGIQISDVYPESWTDSYKELYKDVANCPVEWAKYVEANTQADFICLKFDGSDPN
                     GLDKSVDECADVAKAVIEAIKLPLVVAGSGNHEKDGKLFEKLAQTLDGHNCLFMSAVE
                     DNYKGVGASAGMAYAHKVGAESSVDINLAKQLNVLLTQLGVKGENIVMNVGCSAVGYG
                     YEYVASTMDRIRLAAFGQNDKTLQMPIITPVAFEVGHVKEAIAPIEDEPDWGCPEERT
                     IAMEVSTAASVLVGGSNAVILRHPKSIETIKELVNALA"
     gene            complement(13231..14001)
                     /locus_tag="JAM15_12705"
     CDS             complement(13231..14001)
                     /locus_tag="JAM15_12705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAT6799113.1"
                     /translation="MGYNIAVAGKGGTGKTSLTGLLIDYLVKDKKGPVLVVDADANAN
                     INEVLGIEVEATIGEIREEVNQREKLGNAFPGGMTKAQYLQFRLNSIIEEGEGYDLLV
                     MGRSEGEGCYCFVNGILREQVNKISGHYKYLVMDNEAGMEHLSRKVTRHVDTLLLVSD
                     CSRRSIQAVARIRDLAEELKLSVGRILLIVNKVPNGVMNDGVKEEIEKHNLELIGVVP
                     MDELIYEYDSTGIPLVNLPEDSKSKVAMKEIFAKLELK"
     gene            complement(14057..15442)
                     /gene="lpdA"
                     /locus_tag="JAM15_12710"
     CDS             complement(14057..15442)
                     /gene="lpdA"
                     /locus_tag="JAM15_12710"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HAT6799114.1"
                     /translation="MKIVVVGGGPGGYVAAIKASMLGADVTVIEKRRVGGTCLNAGCI
                     PTKALLASSGVLNTVKEAKDFGIEIDGTVKPNFTAIMERKNKVVNQLISGIEFLFEKR
                     GVNLVNGFGKLIDKNTIEVTKDDGTIETIKADKIILANGSVPVVPRMFPYDGKVVITS
                     DEVLGLEEIPESMLIVGGGVIGCEIGQFFRALGTEVTIVEMVDQILLNEDKDVAKQLL
                     RQFKKDKIKVITGIGVQTCEVVDGKAVATLSNGKVIEAQYALVCVGRRPNLDNSGVED
                     IGIEMERGKVVVNEHLETNVEGIYAIGDIIDTPFLAHVASKEGIVAVENALGKTKVVD
                     YRAIPRCVYTEPEVAGVGKTEKQLEAEGVEYNVGQFDFRGLGKAQAIGHFQGFVKVIA
                     DKETDKIIGAAVVGPHATDLLTELSLAVHLGLTVEQVGDAIHPHPSLSEGLMEALHDV
                     HGECVHSVPKL"
     gene            complement(15486..16367)
                     /locus_tag="JAM15_12715"
     CDS             complement(15486..16367)
                     /locus_tag="JAM15_12715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007061835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5,10-methylenetetrahydrofolate reductase"
                     /protein_id="HAT6799115.1"
                     /translation="MSLLRETLESGKFAVTTEMAPPKGTDLSHLIECAKPLVGRVHAA
                     NVTDFQSAVMRATSLATCKLLKDAGLEPVIQITGRDRNRIAIQGEMLSAGVFGINNLL
                     ALTGDHTSVGDHPQAKGVFDLDSVGILQTAETLMAGTDMAGNKLKGSPDFYLGASVTP
                     EYSPIEVQLLKMQKKIKAGAKFFQTQALYDINTMRKFRELTRDMDCKVLAGIVPLKSP
                     GMAKFMTANVPGIFVPDEQIERLRAAGKENWVSEGIKMAGELIKQLKEEDLCDGVHIM
                     AIGAEENIPAILDAAGL"
     gene            complement(16403..17077)
                     /locus_tag="JAM15_12720"
     CDS             complement(16403..17077)
                     /locus_tag="JAM15_12720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5,10-methylenetetrahydrofolate reductase"
                     /protein_id="HAT6799116.1"
                     /translation="MIISENKPLEEVLGYLKDFDKLVLVGCNQCAATCKSGGEEEVLK
                     MKETLEGEGKKILGYVMLDPACNLLKSKKDLKALKEETKEADAVLSLACGDGTQTIVK
                     NLKDKPVYPANNTLFIGEVQRVGEYEEACKACGDCELGWTGGICPVTMCAKGLMNGAC
                     GGAKNGKCEVNSENDCAWIKIYERLEAIGQLDNLAEIRPPKDYSKQNNPRSLSAKKKK
                     EAAANS"
     gene            complement(17114..17986)
                     /locus_tag="JAM15_12725"
     CDS             complement(17114..17986)
                     /locus_tag="JAM15_12725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 5,10-methylene-tetrahydrofolate
                     dehydrogenase/5,10-methylene-tetrahydrofolate
                     cyclohydrolase"
                     /protein_id="HAT6799117.1"
                     /translation="MEGMSTKGQIIKGKPVADKISEELIKEVDLLIKEGINPKLTIVR
                     VGARSDDLSYERGALKRCQNIGITTEVLELAEDITQEEYIDVLKRVNDDKNVNGILCF
                     RPLPKHLNEEVIKYVIAPEKDVDCFSPINSAKVMEGDKSGFPPCTPTAVVEILKHYNV
                     DLKGSKVTVLGRSMVVGKPVSMLLLSEHATVTICHSKTKNLSGVAAEADVLIAAIGRA
                     KMVDESFVKDGAVVIDVGINVDEEGNLCGDVDTNAVLDKVSMITPVPAGVGSVTTSIL
                     AKHVVKACKLQNNK"
     gene            complement(18078..18710)
                     /locus_tag="JAM15_12730"
     CDS             complement(18078..18710)
                     /locus_tag="JAM15_12730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007061832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclodeaminase/cyclohydrolase family protein"
                     /protein_id="HAT6799118.1"
                     /translation="MKIADKTCVDFVEVLSSKEAVPGGGGAAALVGAIGMALGSMVCN
                     LTIGKKKYAEYEESVKEILSKAGKLEKDLLKMIDDDAECFLPLSKAYGLPKETEEEKR
                     IKAETMEKALKVACEVPLNIVRVCYEAIKLHEDLVDKGSRLAISDVGVGVQCLRAAIL
                     GGQLNVVININSIQDKEYVNKVKIEVDKLVEDGVKICDEVYAKVEKALGK"
     gene            complement(18815..20491)
                     /locus_tag="JAM15_12735"
     CDS             complement(18815..20491)
                     /locus_tag="JAM15_12735"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HAT6799119.1"
                     /translation="MGFKSDIEIAQEAKPQDIREVAKKLGLGEDDVELYGKYKAKVDY
                     NLLKRETGKKAKLILTTAINPTPAGEGKTTTTIGVADAFAKLDKNVLVALREPSLGPV
                     FGVKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMLDNHIHQGNALRIDPK
                     KITWRRCVDMNDRQLRNIVDGMGKKGDGAVRQDGFDITVASEIMAAFCLASDISDLKE
                     RLGNIIVGYSYEGEPVTARQLKANGAMAALLKDALKPNLVQTLEGTPSFVHGGPFANI
                     AHGCNSVIATRMAMHFADYVITEAGFGADLGAEKFLDIKCRMANLKPDAVIIVATVRA
                     LKYNGGVAKADLNNENLEALEKGLPNLLKHVENITQVYGLPAVVAINRFPLDTEAELK
                     LVEDKCKELGVNVALSEVWAKGGEGGIAVAKEVLRLLDEEENNFRFCYEDDLSIKDKI
                     NAIATKIYGADGVDYTPEADKEIANLEKLGFTKVPVCMAKTQYSLTDDQTKLGRPTGF
                     RITVRQATISAGAGFIVALTGEIMKMPGLPKVPAAEKIDVDENGVIAGLF"
     gene            complement(20740..21519)
                     /locus_tag="JAM15_12740"
     CDS             complement(20740..21519)
                     /locus_tag="JAM15_12740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAT6799120.1"
                     /translation="MKIAITGKGGVGKTTFSSMLSRMFAEDGYRVVAVDADPDANLAL
                     ALGFPKEVYESIVPISEMKKLVSDRTAASVGSFGKMFKMNPKVDDIPENFCKEYNGVR
                     LLTLGTVDSGGTGCVCPEHVLLKRLCSHLILQNKDVVVMDMEAGIEHLGRGTAQGVDA
                     FIVVVEPGERSLQTYRKVKKLGHDIGVNKVFVVGNKIRNKEDEEFIIQNLEDGESLGF
                     IYYNQDVIDSDRANQSPYDSSETTKEQIKAIKDKLMSLKDK"
     gene            complement(21829..23748)
                     /gene="cooS"
                     /locus_tag="JAM15_12745"
     CDS             complement(21829..23748)
                     /gene="cooS"
                     /locus_tag="JAM15_12745"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HAT6799121.1"
                     /translation="MDEKMLTIDLNSQKMIAKAREEGVETMYDRKEGFKAQCGFGLQG
                     VCCRICGMGPCRISPKTPRGLCGADEHTIVGRNFARMVAGGTAAHSDHARDIAHTLAL
                     ADPNGNYKIRDEAKLITLAKEWDVETEGRDIYDVAHEVAEIALMEFGKPFGTLRFIKN
                     APEPRQKIWKEYAIEPRAIDREIATIMHSTHIGCTGDIDSLIHMSLRTSMADGWGGSM
                     IGTRLSDILFGTPVPRRTEANLAVLEENKVNIILHGHEPALSEMIVLASEEPDLVALA
                     KEVGADGINLAGMCCTGNEITMRHGVKIAGDFHQQELAIITGAVEAVIVDVQCIFPAL
                     ARVADCYHTKFVTTSPKAKITGSTYIEFREEQALDDAKAIVKEAILNFKNRDKSKVLI
                     PELKSGATVGYSVEAVVNQLDRVVNSHIDPAGTVKPLTDCLKAGVLRGAAGVVGCNNA
                     KGVSNEAHVTIMKELIKNDIIVVTTGCGASAAAKFGLMESDAAEKYAGKGLATVCKLV
                     GIPPVLHMGSCVDISRILDLVGAAANYLDMDMCDLPVVGIAPEWMSEKAVAIGCYVVA
                     SGIDTYLGIMPPIAGSSRAVDILTSELKDKVGATFTVNTNPKELAATIIEDIEKKRVH
                     FEALVEEKMAEKAEA"
     gene            complement(24355..25266)
                     /locus_tag="JAM15_12750"
     CDS             complement(24355..25266)
                     /locus_tag="JAM15_12750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HAT6799122.1"
                     /translation="MIKKLDDILEQLKGGEKIVLSVAAAHDKEVLMAIKDAVERNIIT
                     PILVGNEGKIREISKEIGFDLSGIKIVDKDDIKECAEIAVKLVSSKEADFVMKGLLDT
                     SVILKEVLNKDYGLRTDSLLSHVMVYELEKYHKLLITTDGGMNIAPDYEQKAKILKNS
                     IKAAKALGMETVKVACLAAKEKVNPKMQATVDADMLAKACKEGEFGENVIVEGPLAFD
                     LAVSKEASEIKGFKSEVSGDVDIILVPTIEVGNGIGKAFTYMADSKSAGIIMGAKAPI
                     VLVSRADSHESKLYSIAYGAIVAKNMK"
     gene            complement(25382..25504)
                     /locus_tag="JAM15_12755"
                     /pseudo
     CDS             complement(25382..25504)
                     /locus_tag="JAM15_12755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432270.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
BASE COUNT         7476 a         5266 c         2878 g         9927 t
ORIGIN      
        1 ttctattgaa ttttattatt attttattta gattctattg ttattttact tagaacttat
       61 tattatttta tttaagttct attactattt tcaatcatat aaatttacaa aagactgtac
      121 ataaatttat tttatacaaa cttatctaca gtcttttgtg tgaatatatc taaataatat
      181 cgtatttatt tatttcctct gcacagtgag aatcagaacc taaaactaat ggaatatcgt
      241 atttttttac caactctaat aagtatccat ctatataagg ctctttgcag tactcttttc
      301 tatttccaga aacattataa tcaagttcat aacctttttc tttaattaac tttattaact
      361 cttcaagaat tgtatttcct ttataatcgt atggaaatac ctgattaaac tttctaacta
      421 aatttaaatg acctattctt tttggtttat gtatacctaa atctgaattt acagctttta
      481 tcaatgtttc ataatactta ttataaacag cttcaatact tcctaatttg tcgattaaat
      541 tttgaaactc ctctacactg taatctacac aataataatc atcatcaatt ttaattatat
      601 gtactgataa aagagagtct tctaattcct ttccatattt atttaaattc tcctttattc
      661 cttcttcgta tccttctata aaatccactt ccgacccaac atttatcttg attttaccct
      721 catacttttc tttcaacttc ttgacatcat taaaatactt tggtaaatct tcaatactca
      781 tacaactatc attttcagga gcagggtctc taaattcatt tgcatacgga aaatgttctg
      841 taaatgtcat ttctgttatt ccaacatcca ttgctctttg tacatatttt tcaaaatcat
      901 ccttacttcc atgaggacaa taaggtgaat gtatatgacc atctttcata aataattcac
      961 tcctttttta aagaaaaaat ctaatataaa tgcataaatt ttttaacttc aaaataatat
     1021 ttttaatcat gctaattttt attatatcta atattagagt aattttaaac tgccttttaa
     1081 gtatcttatc tttagtacta ttttcaactt aacattaata ttatttttta acttaacatt
     1141 aatactatct ttaaatagta atactcaata tataattaat caaataactc aaattgtttg
     1201 atgaagcttt tgcagtattt aaagaatata taattattta acattaaata atccaatctt
     1261 gtaataaaat ttactcatta aagtatatta cagaaaatat ctcaaaataa actttttagt
     1321 tcatgatata ctcttttttg catgaaatta gatatatttt tatcatttca acaatgaaag
     1381 ggaggcttac atccatcttg agataacccc ttagataaaa tttttaataa ttaaacatca
     1441 caaaatataa aaatcgctta tatcaaacgt ataagcgatt aattatattt acatatgttt
     1501 tttagcctct aacaacattt tattagcttc ttccatatac tctatagcct tttcaatact
     1561 ctttgctgtt tcttcttttc caatagctct agccttttca acccactctc taaatccttc
     1621 ttcatgagtt tcattgtgat ttatccaatg tactaaaagt atttttaaag ttttttcatc
     1681 cttagactct gatgattcct catgactatg ttcatggtcg tggtcgtgag catggtcatg
     1741 tggatgttca tgacatatat ctccatgagt atgttcgtgg cagtggtcat ggtcatgatg
     1801 tccatgatga tatcttacaa tctctttatc aaaaatcatt agttattccc cctgttattt
     1861 tatattaaac tcttttttta taaggtttac agaatctttt acaagtagtg ctaatggttt
     1921 accttctaat ccaactaact ccacattttc tggcataata ggtaaaagta tcttaagtgc
     1981 ctcactgtct gcaatagctt cacttatatt acaagtaact tctcccatca tagaattagg
     2041 tattattaca gaaataggtg caactattat atttgctttt ttagctgata ctactatagc
     2101 attttcccct gtagctcctt tattagcatg agctttcatc atagaactag ttgctataga
     2161 attagtccct agtgcataaa tttctacata tgtaggtaac tcttctctca aagaagaaac
     2221 tatctgggct ccaatacctc cacccattcc atctatcact gctattatca tatgaaattc
     2281 ccctattaat taattttctt gtattattat cttatggtcc atcaatctta tttctttaat
     2341 tatcccatct attatctttt gctctcctaa taaatccgtt aaataaatct ttccatcaca
     2401 agggtctata ttaaccacat tttccataac cttttctaac tcattattac ttttacaaat
     2461 gaaagctgat gattcacaca tataaatctc ctcctaatat gatttttatt aaaaatcaaa
     2521 aaaagattcc cttaggtatt tcaatacgcc aaagaaacct tcatgatttc agtttttgta
     2581 tattattata ccttaagtat atcactttaa tttatgtaaa gtcaattaaa gttaacgctt
     2641 tttattatac tcttcattct tgtatttttc atatagttct ttaactaatt gcttctcata
     2701 atcagtcaaa tcgccctcca caaactcaac attaaattgt tcagctaatc cctttactat
     2761 gtttttctgt agaatatcta tgtctatttt tctgccaatt tcattttcta ttccacttgc
     2821 ttttttagct gtaaatttca tagctctttc tttcaattct ggtgtcttag tttttattaa
     2881 tttaaacaat ttttctacat caaaatccag tattattgaa ccatgttgta ataaaacacc
     2941 atcttttctg ctttgagcac ttccaattac cttcttatta ttaatagtaa cttcatatga
     3001 tgcatgtgca ttaaaacatg cagctgataa attttcccta cttattctct cgcctctatt
     3061 taaattatct gttcctatac cacttagatt caatccttta actagacctt cacttatata
     3121 tctataagat aggttgatgc tcttatcgat taaaggatta tcttctccta taattatact
     3181 ataagttagc tcattatcat gtaatacagc tcttccacct gtaattcttc tagtatagtc
     3241 tatattcata catctacact tatctaaatc tatctcatct tccaatttct gaaaatatcc
     3301 tatactcaaa caagctggtt cccatgtata aaatctaaga gttggcttat tatgtccttt
     3361 cttatatgca gtaaatatag cttcgtcaat tgccatattc attgctcctt catatgattt
     3421 attatgtata actctccact gattcatgat tattacgccc ccatttttag tataaatata
     3481 tcctagaaat cctctataga tttatttctc ttattgctaa atctatctca ctttgattta
     3541 aaggtcttga atagttgtat atagtacttc cgggtctttc attatagtat ggtctattac
     3601 aatccttaca acctcttatt tcaaaaggat agcctttgtt tatgtctttt aaaatatcat
     3661 tgtcaagctt tatactattt aagtatccat ttttaaactt aaaatactct tttggatacc
     3721 ctttatttat catataagac attaactgta cccttctata actttctatg cttggttgat
     3781 ttatcttttc cattttagtt cctctaactg gagtaaatgc aaataaacta atcgttacat
     3841 cattttcctt taaataaata tataaattgt atatatcttc atgactttca cccataccaa
     3901 ctattatatg tgtacttatt ttattgggat atgattttga catttcagtt ataaatttta
     3961 acttttcatc atagttattt ccttttattt tttcatatag ttctttattt gctgcatcta
     4021 ttgctattcc tattttatca actcctgctg aaaaaaactt ctttatctgt tcatcatttt
     4081 ctaattttgc agatagtgaa attggcatgt ctatcttacc acttatatag tttataaagt
     4141 ctaaaacaga gttatgtgct tcttcacttg ccattgattg aatacatatt ctctttatat
     4201 tttttccttt ataagctttt aaagcatcta atatttcttc ttttgaaaac tctggccaaa
     4261 ttactcttga taatttatct tttctagtac tactttctat tgattgagaa caaaaactac
     4321 atttatttat acatttttct ccaatcatta tatatgctgt tgtaggaggt atatcgcttt
     4381 ttttgtttaa tatcccaagc tctattgctg tcccaactga tagtctaatc ataaaacgca
     4441 acactcctta cactcattta ttgtcatatt catttctata gccttattct ttgcagacct
     4501 tgatggtaat actattctat tgactccaca cattatagat aattggtcta gctcttttct
     4561 atacactcct cttggtctca tacaacctag attaatttca gtatctggta aattaattct
     4621 agcttcacat aaaatatctg ctaccccttc taactcagga ggttctacat tttcatactc
     4681 agtccctttt gttggaataa ggactataaa tgtaagctta ttaggaggat ttttctgtag
     4741 gtattctata atttcatatt caccctttat ttgtcctcct tttaaaccaa tacatatatg
     4801 tggtgctact tctgtatgtt cttgtattgt attataaact tcaatataat cttctttact
     4861 ctttttcatc ttataaactt ctcttattgt ctcatcatca aacactaaat caaaagaaac
     4921 tatatctaaa tacttacaca actctacaat gctatcttta tccataagac ctaaatgagc
     4981 attcaatcta tatcctttct cttttaagtt tttaatggta ttaatatgag tatttatagg
     5041 gacatctccc tcataactac aaccgccact caatagaaag ctagttatat tccttgattg
     5101 tactttttcc tcatattctt ctattggcac catattgttt aagtagtgac cgttgcaatg
     5161 ggcacatttc aaactacatt gattgcttgt agtactaaga gctagtgtct ggttaggata
     5221 agcaaactct attttatttc caaaattctt taatttaata tcaaatgcta ttttcatttt
     5281 ttcagataga ttcttattca tagtttattc cttcttaagt acattttact cttctagtaa
     5341 tttctttgct gttgggaact gctctatatt cgtatgtggt aagaaacatg cagaaataaa
     5401 ttcatccata taacttggat atacactaag ttcaacataa gttatttgat tacctatttc
     5461 ttcaagttta ttttttgcat ctttacttat gagagctaag taagaaccaa caagtgaact
     5521 attccctata taagtaaatt tttctctatc aatgtcagga agtaacccta taattattga
     5581 gttttctatg tctaggttgt ttcctatacc acctgctata taaaccctat ctaatatact
     5641 aaaatccata cctaaactat ctacaagagt gtatgcacct gaatatatag ctcctttagc
     5701 tctgatgaaa ttatctatat caacttcatt gactactata tcattttcta aatcaaattc
     5761 ttctttaaat gctaatacat actctcctat ctcatgctca ttaaatctaa ctctcttatt
     5821 atctaaatcc ctgtatattt tacctcttct atctattaca cctttagtaa tcatttgaca
     5881 gattaaatca attataccag aaccacatat accaactggt gcacattcat caataatctt
     5941 taatgttggc tctaaagttt ctttatcaat aattactttc tctattgctc ctgctgatgc
     6001 cctcattcca cagcttatcc ctccaccttc aaaagcaggt cctgctgaac atgcacagct
     6061 catcatataa tctttatttc caaatacaat ctctccatta gttcctaaat ctataaataa
     6121 aacattttct tcacttgacc atatccctgc tgataataca cctgctgtta tatctcctcc
     6181 tacataactt gcaacagatg gagctaagta cacatatgca ctgtcattta caaaaagacc
     6241 aacattttca cccataagtt ttggagattt taaaaatggt ggtatgtaag gttcttgtct
     6301 taagaagtct gtatacacac ccaagaataa acttgtcata gttgtattcc cggcagccac
     6361 taatgtaact acatcttcct tatctattcc atttctttca tatattgttt ttaatagtgg
     6421 atttatagtt tcctcaacta tagctttatg aagtatctct aatccatttt tcttagttga
     6481 atatataatt ctatttataa catctgctcc atattttatc tgtgcatttc cagaagatgc
     6541 tttatctact acctcttttg aatataggtc tactaaacaa acaactactg aagttgtacc
     6601 aatatctatt gcaactccgt ataaggaatt ttctttattt ccttgttcta tatttatgat
     6661 tgtaagtttc ttttgttttt gaacatatgt tattgtaacc ttaaaatcac tctttctaaa
     6721 tacagttggc atttttctaa gtatatccaa tctaaaatct atttcattat atcctaggtt
     6781 atttctaaca tatctttcca atctatctac atcacttata ttatcatcta aatttggttc
     6841 ttccatttct atgtatttct tttttatatt tgttttaaat tgaaggttat gttcttcaat
     6901 tattttttta gctctttcaa aaatttccct atcctctttt ttattactac cttctatctt
     6961 cataccatgc atagaagatg atactttaga aggaacttca atttctatat ctgatattac
     7021 ctttgtacaa caagctagta tataaccttg ctcccactca tcatctgtta tatgtcttgt
     7081 tttttctgta tcaacttttc cattcaataa ttttacttta cacttcccac aagacacgtt
     7141 tccattacaa ggagcatcta tgaatatatc tgcatttctt gcaacctcta gtaatatatc
     7201 accctcatta caataaacct ctttattgtt tggtgtaaaa ctcactttta tcatgttatc
     7261 cctcccaatt tgttctatat atgataaaag gaaagtatag ctaaatttgc gtgcactcaa
     7321 attttactat actttcccca attataataa tatcttaatc tttaattatt ctaatccagc
     7381 ctcgtattct ttatcactta ataacgtatc aagttcagcc acatcagcta gttttacttt
     7441 taatatccag ttttcatatg ggtcttcatt tatacattct ggctcatctt ctaatttttc
     7501 attaacttcc aatacctcac cattaacagg agatattaaa tcagaagcta ctttagaaga
     7561 ctcaactact ccaaaatcta ctcccttagt tacagtatct tctacttctg gtgtttcaac
     7621 aaacaatatt tctcctaatt gatcttgagc atagtctgtt atacctatat atacaacatc
     7681 tccatcaatt acttttaccc actcatgatc tttagagtat tttaattctg gtaataattt
     7741 catttcgata gacccccaat attatattat tgattaaatt acttaaatca tattaatatt
     7801 atatcatatt attttaaatt ttccatcaat tacattacac tttccatagc taatgctgga
     7861 tgaccttttt cttctaagaa agctaatact ccttcagaat cgtcagctat agtttcatca
     7921 caaaccatat cacagaagtt ttctattcca gtcatttctt taactgtagc atttaattta
     7981 tcagctacat aatcttttaa ttcttttggc atccaaacta ttctttctgg tccaccttct
     8041 gcataagcga attttttaga agatatgaaa tgtcttccgt gtcccataaa tcctggagtt
     8101 tgaactcctc cacctgtcat agaagcaagt tctccgaaag tcataccaac tggagtaaca
     8161 cttgcaaatt ctctgttaac tacaacaaat ccgtttgctt ctggcattat accacagata
     8221 cattcgaagc atccacaaga agtcattggg tcttctagta tagaatataa tgtaacagat
     8281 tcaactgcac cttgagatat ttggtttaca gtttcattta ctgaattcca tacacctgtt
     8341 ctatcatcta agcactcgcc tttttctatt ggttgacaag gacctgttgg gtctaattct
     8401 ttagtagcct tagcatctaa ccagctaact gctccacaaa gaccaagtct ttcaggagta
     8461 acaacacaaa cgtgagctgg tgcaaatgat tgacataagt tacaagaata gaaagtatca
     8521 acactttcat caactaatga agctaatctt tcatctctag cattgtactt agctattgct
     8581 tctcctttta attcagacac tttttcagca tctgtaatta tagttatttc acacttatca
     8641 actactgatt caaattcatc taacatctta gcatataaaa cttctcctat atgctcaagt
     8701 ctaaatcctt tatcaaatgc atctttagag attcttaccc aagccatatc tctttgtcca
     8761 acgtgcatta caccttctat atagttcaag aagtagtgga aacgtctttc aagaactggc
     8821 tcgaaatctt cttgcatatt tttaccagct attttaacta ttacagcaag tggtaatctt
     8881 aatacaccat ctgcatcaac ttcatctata tttggtccta ttatttctat cttatggtct
     8941 tcaacttctg ttgcttcttt cttaacaaca agctcccaag cttcagttct gtttccacca
     9001 aactcagcaa acatatcgct ctttctaatt ctctcacctt caaatgctgc tgcaaatgaa
     9061 actgggatag gtatttcagt aacttttatt tttattcctc tagcttctaa tgaagtagct
     9121 actatcttat cataatcttt ttgagttaat aggttcattg gaacttcaag aactgtttgg
     9181 tcagttataa ctgggaatcc taaagctatt gctccagcac ctgcagatac aactaattca
     9241 cttaatggtc caaatgcatt aacaaatgca ggaactctat tagctgtgta ctctaataat
     9301 ccgtttaaat caccaggagt taatccaccg aatattaatg ctgctcttac tgcaacagat
     9361 acaacgtgta taacagaagt tacatcatat cctagaggta taactcttag ctcaagaccc
     9421 atttttactc cagcttctat agcttggtct ataactttac caactaagaa agttagtaaa
     9481 cctttagatt ggtaatcttt tataactttt gctgctgatt ctgcatctgg acactcacca
     9541 agaacaactg caacaccagg tatatctcct gtaactaatg gtacaccaag tgatctgatt
     9601 atagggtcag ttatatgacc tgcacatggc tcactatatg gagcatccat agttgaatat
     9661 tttaatgctt caattacttc tgcagctaaa gccgtagcta aaccagcatt aaaagcatgt
     9721 tctagtaaat gagttctatt tattaaagat tttactactt ctaaagcacc ttctaagtcc
     9781 cctaaagtgt tcatcttttg tcctgttgca gcatatatac aaggtaatga atatgctgta
     9841 tcagggaaag caactttatg ctcttttcca ttcttttcta tagcttcagc taacatagct
     9901 tgagccgcac ctaaagcttg ttctgaccct gtaaagatta tattatatag attcattcta
     9961 tttccccctt taatatttac acctattttt tattaactat accctaaaaa ccctagaaag
    10021 caaatccacc ttcatttaac tctaagaaag agtctgcata taaagatgcc ccgttgatta
    10081 tgtcacaaga ttttacagtt ttcattaatt ctgggtcaca tggattcatt atagctgaac
    10141 taaatccatt agccattgcc attgctaaga atgcactatc taaaacaggt ctaacatgct
    10201 taggacatcc attagatacg ttagataatc ctcctgtagt taaaagtccc atctcagtca
    10261 tcatttttat agcttctaaa acttctactt gtttttcttg catacctttt ataactaagc
    10321 ataatgggtc aaatagtata tcagttggtt ccattcctaa cattaagcct ttttctaata
    10381 tttcttggca gtaagccata cgctcatcat tatctcttgg gataccttct tttgcacata
    10441 aacctataac cattgcttcg tattcagctg ctatatctat taaatcaaat cttgaaccag
    10501 catcagcaga gtttattatt ggttttgcat tagttctatc ataaacttta agtccagctt
    10561 cgatagcttt tttattagct gtatctaatg ctataggaac attgttgaac tcagattgaa
    10621 gtaatttgat tccccatgtc attatttctt cgccatctct ttcggcaggt cctatattaa
    10681 aatctatata gtgtgctcct gcttctaatt gctcttttgc tctttttaag attggagctg
    10741 ggtctctttc tgctaatgct tttcttattg aaggtgatat acaatgtatt ctctcaccta
    10801 taatcataaa tttttccatt tataatgtcc ccctttaaat ttaatattaa tagttagtta
    10861 atattttatt agtttgtttg gcatgctttt tcttggtatc cttttaagaa cttaggtaat
    10921 tccatagatt cctctggtcc tataactaca ttccatcctg gtaagttatc ttctatatca
    10981 cctttaagta ccgcaacttt tcctggaatg ataaggtctt tacaattagt tacttcttct
    11041 accttacttt ctttaatgaa agcagagatt gagtttccac caaatttacc agcagcccaa
    11101 gatgtaagaa ctgaatatcc acctgcatct ggtattacta accatactgg aacttttgat
    11161 ctttctatat caccagcaac tatgaagtaa gttaatgcaa agtcaacagt aactaatact
    11221 ggagaatttt catctgggtt gttgattgga taaatctttg gttcaactct cattggtctt
    11281 tgtgggtcag tgtatatatt ttgtcttagt gcaaataatg gtaatgcctt agcgtaactg
    11341 atatcatcta ttactattat agaaccgtat tttatagtga atattgatga taaagcaact
    11401 tccatcatag ggtttgaatt agataatcta tttgcaaata ctattgaagg atatccaaat
    11461 gttctatctt gctcttttaa agctattctt ctaacttgta tagcattagt gtaagtatct
    11521 tttatgtttt ctcctgttac atctaatact aattctttat atccagcggc ttgaattaat
    11581 tcaactgttt catataattc ttctaagcta ccagctttta cacctaatgg taaacttgct
    11641 cctttaacta cttctatcat atctttgtag ttctctttag ttgctccata taccattggt
    11701 ctagcatctt ttaatacttc aacagcttct ttaactactt gtgcatcatc acaagctaaa
    11761 atataagcta cttctaatcc actgcctttt attttatcta ttaattttaa atacgcatct
    11821 ttatctccac aatactctaa aacagccatt tcaactttca tttgttcacc aattcttaca
    11881 tagtcaactt ttttcatgtt agctatttta gcatctactg cttcatcact catacaagta
    11941 cagaatgaaa ctgcatatct atttctactt actaatgttt tttcatgtct aaataatact
    12001 gtttctccac ctagttcata ctcagatgca ccagcaccaa cttttaaagc tttcattaaa
    12061 ggtgcagtag cctctgataa ttttgctata gcgtcatcag acatatgtgg gcatttacct
    12121 acttctacag ctcctgaagc aaccttcata gagaaagcca tacaagttgg gaatccacaa
    12181 tccttacagt ttttctttgg tgttaattta aatatatcta aagcttttaa tgccattatt
    12241 ttttccccct aaccttaaca atttaattaa gctaatgcgt taaccaattc ttttatagtt
    12301 tctattgatt ttggatgacg aagtataact gcgtttgaac cacctactaa aacacttgct
    12361 gcagttgaaa cttccattgc tatagttctt tcttctggac aaccccaatc tggctcatct
    12421 tctattggag ctatagcttc tttaacatga cctacttcaa aagctactgg tgttatgata
    12481 ggcatttgta atgtcttatc attttgacca aatgctgcaa gtctaattct atccatagta
    12541 gatgcaacgt actcatatcc ataaccaact gctgaacatc caacattcat aactatattt
    12601 tcacctttaa cgcctagttg agttaacaat acgtttaatt gtttagctag gtttatatca
    12661 acagaagatt cagctcctac tttatgtgca taagccatac cagctgatgc tcctactcct
    12721 ttgtagttat cttctactgc tgacataaat aagcagttat gtccatccaa tgtttgagct
    12781 aatttttcaa ataatttacc atctttttca tgatttcctg aaccagctac aactaaaggt
    12841 aattttattg cttcaattac tgccttagct acatcagcac attcatcaac tgacttatct
    12901 aatccatttg ggtcagaacc atcaaatttt aaacaaataa aatctgcttg tgtattagct
    12961 tcaacatatt tagcccactc tactggacaa ttagctacat ctttgtataa ttccttatat
    13021 gaatcagtcc agctttcagg ataaacgtct gatatttgta tacctatttt tggagaatta
    13081 cctacttctc catcaaaact ataaaaaggt aatacatttt ccccacctaa tttaattgct
    13141 ttttccccta ttcctacttc aacttctgat atttttccag aatatttttg agtagacatt
    13201 ttaaatgcca tatttttttc ccccttaagc ctattttaat tctaatttag caaaaatttc
    13261 tttcatagcc actttagatt ttgaatcttc aggtaaatta actaaaggaa tacctgtaga
    13321 atcatattca tatatcaatt catccatagg tacaacaccg attagctcta ggttatgctt
    13381 ttcaatttct tctttaacac catcattcat aaccccattt ggaactttat ttacaatcaa
    13441 aagtattctt ccaacactta actttagttc ctcagctaaa tctcttattc tagcaacagc
    13501 ttgtatgcta cgtcttgagc aatcactaac caataaaagt gtatcaacat gtctagtgac
    13561 ttttctactt agatgttcca taccagcttc gttgtccatg actaagtatt tgtaatgacc
    13621 agatattttg tttacttgtt ctctaagtat cccatttaca aaacagtaac atccttcacc
    13681 ttctgaccta cccattacta ataagtcata tccttcgcct tcttcgatta tagaatttaa
    13741 tctaaattga agatattgtg cctttgtcat accaccaggg aatgcattgc ctaacttttc
    13801 tctttgattt acttcttctc ttatttctcc tattgttgct tcaacttcga tacctaacac
    13861 ttcatttatg ttagcattgg catcagcatc tacaactaat actggtccct ttttgtcctt
    13921 aaccaaataa tcaattaaaa gccctgtgag acttgtttta ccagttccac cttttcctgc
    13981 aacagctata ttgtatccca ttttaagact tcccccttaa atctagccac agagccttat
    14041 gtactctgtc tgtctattat aatttaggta cagaatgaac acattctcca tgtacatcat
    14101 gaagtgcttc cattagccct tcagataaac ttggatgtgg atgtattgca tcccctactt
    14161 gttctactgt taatcctaga tgaacagcaa gtgacaactc tgtcaataaa tctgtagcat
    14221 gaggtcctac tactgctgca cctattatct tatcagtttc tttgtcagct ataactttta
    14281 caaatccttg gaaatgtcct atagcttgtg cttttccaag acctctaaaa tcaaattgac
    14341 ctacattgta ttctacacct tcagcttcaa gttgcttttc agtcttacca acaccagcaa
    14401 cttcaggttc agtataaaca catcttggaa ttgctctata atctactacc ttagtcttac
    14461 ctaaagcatt ttcaactgct acgatacctt ctttagaagc aacatgtgct aggaaaggag
    14521 tatctattat atcgcctatt gcgtatatac cttctacatt agtttcaaga tgttcattaa
    14581 ctactacttt tcctctttcc atttcaattc ctatatcttc tactccagaa ttgtcaaggt
    14641 taggtcttct accaacacat actaatgcat attgtgcttc tataaccttt ccattagaaa
    14701 gagttgcaac cgccttacca tcaactactt cacaagtttg tactccaata cctgtaataa
    14761 ccttaatttt atctttctta aattgtctaa gtagttgttt agctacatct ttgtcttcat
    14821 ttaatagtat ttggtcaacc atctcaacta tagttacttc tgttcctaag gctctaaaga
    14881 actgccctat ctcacatcct ataactccac cacctactat taacatagac tcaggtatct
    14941 cttcaagtcc aagaacttca tcactagtta ttacaacttt tccatcatat gggaacattc
    15001 ttggtacaac tggaacagaa ccatttgcta gtattatctt atctgctttt atagtttcta
    15061 ttgttccatc atctttagtt acttctatag tgtttttatc aattaatttt ccaaaaccat
    15121 taactaagtt tactcctctt ttttcaaata agaactctat accacttatt aattggttta
    15181 caactttatt ttttctttcc attatggcag tgaagtttgg cttaactgta ccatctattt
    15241 ctataccaaa atcctttgct tcttttacag tattcaatac tcctgaagaa gcaagaagtg
    15301 ctttagttgg tatacatcct gcatttaagc aagttcctcc aactcttctt ttttcaataa
    15361 ccgttacatc tgcaccaagc atagaagctt ttatagctgc tacatatcct cctggtccac
    15421 cacctactac tactatcttc atccttaatt cccccaaacc taatataatc tacaatcttg
    15481 caatactata aacctgcggc atccagtata gcaggtatat tctcttctgc cccaattgcc
    15541 attatatgaa caccatcaca taaatcttct tcttttaatt gtttgataag ttcccctgcc
    15601 atttttattc cttcacttac ccagttttct tttccagctg ctcttaatct ttcgatttgt
    15661 tcatctggaa cgaatattcc tggtacattt gcagtcataa atttagccat tcctggtgat
    15721 tttaaaggta ctattcctgc taataccttg caatccatat cccttgttaa ttctctaaac
    15781 tttctcattg tatttatgtc ataaagtgct tgtgtttgga aaaatttagc ccctgctttt
    15841 atcttctttt gcatttttaa taattgaact tctattggag aatattctgg agttactgat
    15901 gctcccagat aaaaatctgg agaacctttt aacttattac cagccatgtc cgtacctgcc
    15961 attaaagtct cagcagtttg aagtatcccc acagaatcta aatcaaacac tcccttagcc
    16021 tgtggatggt ctcctacgct agtatggtct cctgttagtg ccaacaaatt gtttatccca
    16081 aatacacctg ctgacaacat ttctccttgt atagctattc tatttctatc tctccctgtt
    16141 atttgaataa ctggctctaa tccagcatct tttaataatt tacatgtagc aagagaagtt
    16201 gctctcataa ctgccgattg aaagtctgtt acatttgctg catgaactct tccaactaac
    16261 ggctttgcac attctattaa atgtgaaagg tcagtccctt ttggaggagc catttcagta
    16321 gtaactgcaa attttccact ttctaatgtt tctcttaata agctcatctc taatccccct
    16381 tttaaccttc taaaaaaaac ttttatgaat ttgctgctgc ttctttcttt ttctttgcac
    16441 ttaaacttct tggattattt tgcttagaat agtcttttgg tggtcttatt tctgctaagt
    16501 tatctaattg tcctatagct tctagtcttt catatatctt tatccaagca caatcattct
    16561 ctgagtttac ttcacactta ccatttttag ctccaccaca agccccattc ataagacctt
    16621 tagcacacat agttactgga catatcccac ctgtccaacc aagttcacag tctccacaag
    16681 ccttacaggc ttcttcatat tctccaactc tttgtacttc ccctataaac aaagtattgt
    16741 tggctggata aactggctta tcttttaaat tcttaactat tgtctgtgta ccatctccac
    16801 atgctaaaga taaaactgca tcagcttcct tagtctcttc ttttagagcc tttaaatcct
    16861 ttttagactt taaaaggtta caagcagggt caagcattac atatcctaag atttttttgc
    16921 cttcaccttc aagagtttcc ttcattttta aaacttcttc ttccccacca cttttacaag
    16981 ttgctgcaca ttgattacaa ccaactaaaa ccagcttgtc aaaatccttt aagtacccta
    17041 gcacttcttc taatggttta ttttcagaaa ttatcatatc tacttccccc ctaaaccttc
    17101 cacatatata tatctattta ttgttttgta atttacaagc cttaactaca tgttttgcaa
    17161 gtatagatgt cgtaactgaa ccaaccccag ctggaactgg agttatcatt gatactttgt
    17221 ctaaaactgc atttgtatca acatctccac ataaatttcc ttcttcatca acatttatac
    17281 caacgtctat aactaccgct ccatctttaa caaaactttc atcaaccatc ttagctctac
    17341 caatagctgc tattagcacg tctgcctctg ctgctacacc tgatagattt ttagtttttg
    17401 aatgacatat tgtcacagtc gcatgttcac ttaataaaag cattgatact ggctttccaa
    17461 ctaccattga tcttccaaga actgttacct tacttccttt taaatcaaca ttatagtgtt
    17521 ttaatatctc aactactgct gtaggtgtac atggtggaaa tccactttta tccccttcca
    17581 ttaccttagc agagtttatt ggactaaaac aatctacgtc tttttccggt gcaataacat
    17641 attttataac ttcttcattt aagtgttttg gaagaggtct aaaacataat ataccattaa
    17701 catttttgtc atcattaact ctctttaata catcaatata ttcctcctgt gttatatcct
    17761 cagctaactc taacacttct gttgttatac ctatgttttg acatctcttt agtgctcctc
    17821 tttcataaga taaatcatca cttcttgccc caactctaac tattgttagt ttaggattta
    17881 taccttcttt aattagtaaa tcgacttctt ttattaattc ttcactaatt ttatcagcta
    17941 caggttttcc ttttataatt tgtcctttag ttgacattcc ttccatacat tcacaactcc
    18001 cctacaagca aacttaaatt aatttattct atataccaca tattaataac atagtatcta
    18061 ctttcgtcat ttaaaaatta ttttccaaga gctttttcaa ctttggcata aacttcatca
    18121 caaattttta caccatcttc aactaactta tctacttcta tttttacctt attaacatat
    18181 tctttatctt gtatagaatt tatatttata actacattta attgtccacc aagtatagca
    18241 gctcttaaac actgaactcc tacaccaaca tcacttatag caagtcttga acctttatca
    18301 actaaatctt catgtaactt aatagcttca tagcaaactc ttactatgtt taatggtact
    18361 tcacaagcaa cttttaatgc cttttccatt gtttctgctt ttattctttt ttcttcttct
    18421 gtttctttag gaagcccgta agcttttgat aatggtaaga aacattctgc atcatcatct
    18481 atcattttta ataaatcttt ttctaacttt cctgccttac ttaatatctc ttttacactt
    18541 tcttcatact cagcatactt cttcttccct attgtaaggt tacataccat actacctaaa
    18601 gccataccta ttgcacctac tagtgcagca gctcccccac cacctggtac tgcttctttg
    18661 gaagatagta cttctacaaa atcaacacaa gttttatctg ctattttcat gataatcctc
    18721 cttgaaagga tgtaggaaaa tatctcaaat tattcgagat attttacgaa ctattttaag
    18781 atatctccta ctctttattt ataaattaat ttccttagaa taatccagct attactccat
    18841 tttcatcaac atctattttt tctgctgctg gaacttttgg taatcctggc atcttcatta
    18901 tttctccagt aagtgcaact ataaatccag ctcctgctga aattgttgct tgtcttacag
    18961 ttattctaaa tcctgttggt ctacctaatt tagtttggtc atcagttaaa gaatattgag
    19021 tcttagccat acatactgga actttagtaa atccaagttt ttctaagtta gctatttcct
    19081 tatcagcttc aggagtataa tctacaccat ctgctccata aatcttagta gctatagcat
    19141 ttatcttgtc ttttatagat aaatcatctt catagcagaa tctaaagtta ttttcttctt
    19201 catccaataa tcttaaaact tctttagcta ctgcaattcc accttctcca ccttttgccc
    19261 atacttcaga aagagcaaca ttaacaccta attccttaca cttgtcttca acaagtttaa
    19321 gttcagcttc agtatcaagt gggaatctat tgattgcaac aactgctggt aatccatata
    19381 cttgagttat gttttcaaca tgttttaata agtttggaag tcctttttca agagcttcta
    19441 ggttttcgtt atttaagtct gctttagcaa ctccaccatt gtattttaat gctcttacag
    19501 tagcaactat tataacagca tctggtttta agtttgccat tctacatttt atatctaaga
    19561 atttttctgc tccaaggtca gcaccgaaac cagcctcagt tattacatag tctgcaaagt
    19621 gcatagccat tcttgtagct ataacagagt tacatccatg agctatattt gcgaatggtc
    19681 caccgtgtac aaatgatggt gttccttcaa gagtttgaac taggtttggt tttaaagcat
    19741 cttttaataa tgcagccata gcaccattag cttttaattg tctagctgtt acaggttcac
    19801 cttcgtaact gtatccaact attatatttc ctaatctttc ttttaaatca gatatatcac
    19861 ttgccaaaca gaacgctgcc attatttcag aagcaacagt tatatcaaat ccatcttgtc
    19921 taactgctcc atcacctttt ttacccatac catcaacgat atttctaagt tgtctatcgt
    19981 tcatgtctac acatcttctc caagttattt tcttagggtc tattctaagt gcatttcctt
    20041 ggtgaatatg gttatcaagc atagcagcta aaagattgtt agcagctcct atagcgtgaa
    20101 aatctcctgt gaagtgtaag tttatatctt ccataggaac aacttgtgca tatcctccac
    20161 cagctgctcc acctttaaca ccaaatactg gtcctagaga tggttctctt aaagcaacta
    20221 atacattttt gtctagttta gcaaatgcat cagcaacacc tatagtagta gtagtttttc
    20281 cttcacctgc tggagttggg tttatagctg tagttagtat taacttagct tttttaccag
    20341 tctctctttt tagtagattg tagtcaactt ttgctttgta tttaccataa agttctacat
    20401 catcttcacc tagtcctaat ttttttgcaa cctctctaat atcttgaggc ttagcttctt
    20461 gagctatttc aatgtcagat ttaaatccca taactgaatc tcctcccaca acctaaatag
    20521 atttaaaata taatttttgt aaaaattgta ttaatatgta aaaattatat tttataagat
    20581 aattatacat gtaaaattac ttaaaaacta gctactaagc tattaaaata ttcaaactta
    20641 atagctagtt atttatctaa ttacttactt attacctatc tattgcctat gtctaacctt
    20701 taaccaactt aaaatcccaa atcaaaattt ctatctattt tatttatcct taagtgacat
    20761 taatttatct tttattgctt taatctgttc tttcgttgtt tcactagaat catatggaga
    20821 ttgattagct ctatcagaat caataacatc ttggttatag taaataaatc ctaaagattc
    20881 tccatcttct aagttttgga ttataaattc ttcatcttcc ttatttctaa ttttatttcc
    20941 tactacaaat actttattta cacctatatc atgtccaagt ttcttaactt ttctataagt
    21001 ctgtagactt ctctctcctg gttctacaac tactataaaa gcatctacac cttgggctgt
    21061 tcctcttcct aagtgttcaa ttcctgcttc catatccata accactacat ctttattttg
    21121 tagtattaaa tgtgagcaga gtctcttcaa aagaacatgc tctggacata cacatccagt
    21181 accaccagaa tctacggttc ccaatgtaag taatcttact ccattgtatt ctttacagaa
    21241 attttcaggg atatcgtcta ctttaggatt catcttaaac atttttccaa atgaacctac
    21301 agaagcagct gttctatctg aaactaattt tttcatttct gatataggta ctattgattc
    21361 atatacttct tttggaaaac ctagtgctaa agctaaatta gcatcagggt cggcatcaac
    21421 agcaacaact ctgtatccgt cttcagcaaa catcctagag agcattgaag aaaaagtcgt
    21481 tttacctact ccacctttac ctgttattgc tatcttcata atccctacca ccttttatta
    21541 ctatttgctt tttagtagtt aattttacag ttaaatattt tttacactct atatttttat
    21601 acactaaaaa taaactacag ctagtcctta caggaaccaa ttaaatttac cctactagct
    21661 tttcaaagca gcatgtatag ttttattatt ctttaatatt gtttatattt tatttattca
    21721 gtatattcat tatattttga tgttctttac tttaatattt gactttattc aactttactc
    21781 aaccagaaac ttcttataaa aaagtttatt ctataacttc actatttttt aagcttcagc
    21841 cttttctgcc attttttctt caactaatgc ttcaaagtga acacgttttt tctctatatc
    21901 ttctattatt gtagctgcta actcttttgg atttgtattt acagtaaatg tagctccaac
    21961 tttatctttt aactcactag ttaatatatc cactgctctt gaagaaccag ctattggagg
    22021 cattattcct aaataagtgt ctataccaga agctacaaca tagcatccta tagcaactgc
    22081 tttttctgac atccattctg gagctatacc tacaactgga aggtcacaca tatccatatc
    22141 taagtaatta gctgctgctc caactaaatc tagtatacga cttatatcaa cacaagaacc
    22201 catatgtagt actggtggga ttcctactaa tttacagaca gttgcaagac ctttacctgc
    22261 atatttttca gccgcatcag attccattaa accaaactta gctgctgctg aagctccaca
    22321 acctgtagta actactatta tgtcgttttt gattaattct ttcattattg ttacgtgagc
    22381 ctcatttgaa actcctttag cattgttaca tccaactaca ccagctgctc ctcttaatac
    22441 tccagctttt agacagtctg ttaatggctt aactgttcct gctgggtcta tatgagagtt
    22501 tacaactctg tctaattgat ttactactgc ttctacacta tacccaactg ttgcgcctga
    22561 ttttaattca ggtataagta cttttgattt atctctattt ttaaagttta aaatagcttc
    22621 tttaactatt gctttagcat catcaagtgc ttgttcttct ctaaattcaa tataagttga
    22681 acctgttatc ttagcttttg gagaagttgt tacaaattta gtatggtaac aatctgcaac
    22741 tctagctaat gcagggaata tacattgaac gtcaactatt acagcttcaa ctgctccagt
    22801 tattattgca agttcttgtt gatggaagtc tcctgctatt tttacaccat gtctcattgt
    22861 aatctcatta cctgtacaac acatacctgc taagtttatt ccatcagcac caacttcttt
    22921 agctaaagct actaagtctg gctcttctga tgctaaaact atcatttctg ataatgctgg
    22981 ctcatgtcca tgtaatatta tgttaacttt attttcttct aatactgcta aattagcctc
    23041 tgttcttctt ggcactggag ttccaaataa gatatcgctt agacgagtac ctatcataga
    23101 accaccccaa ccatcagcca tagaagttct aagactcatg tgtattaaac tatctatatc
    23161 accagtacat cctatatgag tagagtgcat tattgttgca atttctctat ctatagctct
    23221 tggctctata gcgtattctt tccatatttt ttgtcttggt tctggtgcat tttttataaa
    23281 tcttaatgtc ccaaaaggtt ttccaaattc cattaatgca atttctgcca cttcatgtgc
    23341 tacatcatag atatctctac cttctgtctc tacatcccat tctttagcta aagtaattaa
    23401 cttagcttcg tctcttattt tatagtttcc atttggatca gctaatgcta atgtatgtgc
    23461 tatatctcta gcatggtctg aatgggcagc tgtcccacca gcaaccattc ttgcaaagtt
    23521 tctacctact atagtatgct catctgctcc acataacccc cttggagtct tagggcttat
    23581 tctacatggt cccattccac atattctaca gcaaacacct tgaagaccaa aaccacattg
    23641 tgccttaaag ccttcttttc tatcatacat tgtttctacg ccttcttctc tagctttagc
    23701 tatcatcttc tggctgttta aatcaattgt taacattttt tcatccatat tcctatcccc
    23761 tttttttgat ttttaaaatc ccccaggtga ctgacttcat gtcataaaat aataaaataa
    23821 atgctttcta agttgattat atactaattt tcagtgcttt gctttagatt taaatatttt
    23881 tttaacaaaa ttagataata cataaaaatt ttattttcta cacttaattt aagttgattt
    23941 tatcgcttgt ttttggctat ttgttaatat ctaaacctac ttttttgata cttcagttta
    24001 attaaattat gttttgattt ttttaaatca aatttgaaat ttttctagtc atttttatat
    24061 tattgcagat tgtttgtgta tttattatct ttcactactg tttggactta ttacagattt
    24121 ttactcccta aacttaatta gtaaaaactt cttagaatag cattttttgg actaattttt
    24181 ttgaattttt ttatttttcc tactttaata ttaattatag cttcaaattg aacatttgta
    24241 tatattcatt tgaagctata attatttttt atataaaact tttttaatac agcattaatt
    24301 tagacatttt gactattttt tctactttaa ttcatttatt tcaaacgatt tatcctattt
    24361 catattttta gctacaatag ccccatatgc aatagaatat aatttagatt catgtgaatc
    24421 agctcttgac actaaaacta taggagcttt tgcacccata attatacctg ctgatttaga
    24481 gtctgccata tatgtaaagg ctttccctat tccattgcca acctctattg ttggaaccaa
    24541 tatgatatct acatctccag atacttcact tttaaaccct tttatctcac tagcttcttt
    24601 tgaaacagct aaatcaaaag ccagaggacc ttctacaatt acattttcac caaattctcc
    24661 ttctttacaa gcttttgcta acatatctgc atctacagtt gcttgcatct taggatttac
    24721 tttctcttta gctgccaaac atgcaacttt tacagtttcc attcctaaag cttttgcagc
    24781 ttttatagaa ttttttaata tctttgcctt ttgttcataa tcaggagcta tattcatacc
    24841 tccatctgta gttataagta atttatggta tttttctaac tcatatacca taacatgact
    24901 taataaacta tcagttctaa gaccatagtc tttatttaac acttctttta atatgacaga
    24961 tgtatctaat aatcctttca ttacaaagtc ggcttcttta cttgatacta atttaactgc
    25021 tatttctgca cactctttga tatcatcctt atccactatt ttgataccac ttaaatcaaa
    25081 tcctatttct tttgatattt ctcttatttt gccttcattt ccaaccaata taggagtaat
    25141 tatatttctt tctacagcat cctttattgc cattaaaact tctttatcat gagctgctgc
    25201 tacagagagt acaattttct ctcctccctt aagttgttct aaaatatcat ctaatttttt
    25261 tatcaaaagt aacccctccc ttatatatat ttaactaaat aataccatat ttgctatacc
    25321 ttttctcaat ttatttttta tgttataaag aatttatata actaaaagac agtttaatat
    25381 tttattctgg gatttcatca atagctctta aaagctttgc aggaacacca cctacaatag
    25441 tattttttgt tacaactgct ccagcagcga taattgcatt atctccaata gtaactcctg
    25501 gaactcttca tacaaaaaag aggcttatct ctattttagt ataatcc
//
LOCUS       DACTZW010000060        25474 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.060, whole genome shotgun sequence.
ACCESSION   DACTZW010000060 DACTZW010000000
VERSION     DACTZW010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25474
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.060"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            136..1101
                     /locus_tag="JAM15_12760"
     CDS             136..1101
                     /locus_tag="JAM15_12760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HAT6799123.1"
                     /translation="MSKLKKFVILLAFLVVIFPISVYGYFYYKLSAIHDSSISSDLLD
                     NNDHKNEDGIINILLMGTDARPNEDSSRSDAMMILTIDNKHNDIKLTSLARDSYVDIP
                     GHGKQKLTHAYAYGQADLLIQTIEENFNIDIQNYACVNFESFMYIIDAIGGVEVTVEK
                     GEIRELNKFIPETYKWNKNDDKGSIQYIRNSGKQTLNGYQALSFARIRHNDTAFARDG
                     RQRQIIQAIIKKTETLPVTKYPGLLDAVLPYVKTNMKPNAILSLGAQVLKMGDLNIKQ
                     FEFPIDDEIHSTGGIYGKAGWVLRFDPDTLDILHDFIFNDIEFKQ"
     gene            complement(1299..3410)
                     /locus_tag="JAM15_12765"
     CDS             complement(1299..3410)
                     /locus_tag="JAM15_12765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding glycosyl-hydrolase Cwp19"
                     /protein_id="HAT6799124.1"
                     /translation="MKKISILVLSLIMTLTMCSVSSFADSSNDKEMRAAWISTVYNLD
                     WPKTKNNEAKQKKEYTDLLDKLKSVGINTAVVQVRPKSDALYKSNINPWSEYLTGTQG
                     KDPGYDPLPFLIEEAHKRGMEFHAWFNPYRITMADESIDKLPANHPAKKNPSWVVKHG
                     NKYYYDPGLPEVRKYIVDSIAEVVQNYDIDGVHFDDYFYPGVSFNDTATYQKYGKGQN
                     KDNWRRENVNTLLRDVKASIKSIKPNVVFGVSPAGIWRNKSSDPTGSDTSGNESYVGT
                     YADTRAWIKQGLIDYVVPQLYWPIGLKAADYSKLVAWWANEVKGTNVDLYIGQGIYKQ
                     GQSSYGGQNIAKEIVQQVTLNRKYSEIKGSMYFSAKDIANSTSIQKDLKSLYSSSEEP
                     VTPPSNVKVEKLRGDERYDTAVAISKKGWATNSDTVVLVNGYSIVDGITSTPLATSND
                     APILLVNKDNIPTSTKNELKRLNPSKVILIGGNNSIGDKVESEIKDTLSNVSINRVGG
                     SDRYSTSLMIAKELVKTNPVEKLYITSGTGEADSLSIASKAGEEKQPIVLVSKDNVSD
                     EVYNWISDLKVKDAYFIGGNLSISDSVINKLDKVITNDVSKNRIAGENREETNGKVIQ
                     KFYPNAEYSSMFVSKSNQLVDALTSGPLAAKLKSPVVMLGNSVTSAQKTALEPKKTAL
                     VYEAGDGINQNTLNTFLNLVK"
     gene            complement(3712..4419)
                     /locus_tag="JAM15_12770"
     CDS             complement(3712..4419)
                     /locus_tag="JAM15_12770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HAT6799125.1"
                     /translation="MMNIKNKKHILKKFIAMVLIAGVVTVEAGAITASAAEPTNSPMS
                     ATVDQCDFLNVRSGASANDAVVGKINTGDKVEVLELHSNGWIKIKSVDNVTGWVNGDY
                     LTIQGGNVDAKVQNVLNLAFKQQGKPYRWGATGPNAFDCSGFTSYVYKNGAGVNLPRV
                     SRSQATVGKKVSRAELKPGDLVFFGSGGSINHVGLYVGDSKFIHSPQTGDVVKVTSMA
                     PGTNYARRLITATRVLQ"
     gene            complement(4618..6531)
                     /locus_tag="JAM15_12775"
     CDS             complement(4618..6531)
                     /locus_tag="JAM15_12775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAT6799126.1"
                     /translation="MRESIDLEKESFFNRLFKKYKFRHLTLLILDICSVLVAFRMSLS
                     LTGNLNAFTTNDIIISVCIYIVLHIVSFRLFKCYNTLWRYAGEEEIISIFVATLAYLI
                     PIYIINKLLGFDYPIMFYVLNTIFIIMFTSGARIAYRAIRIVMNKTYSRGKVSNILII
                     GAGDAGEMVIQELKRNSELKKVAVAIIDDDKNKIGRIIHNVKIVGTTSDIKDVVEKYN
                     VDEIIFSIANIEKRRKKEIIDICKNTNCKIKTIPGIYEIIDGKVDIKQIREVEIEDLL
                     GREPIKTNLREISNYIEGKVILITGGGGSIGSELCRQIAGFNPKELIIVDNYENNAYS
                     IQQELLRKYKNKLDLKTVIASIREEKRMDEIFNKYKPEVVFHAAAHKHVPLMESSPGE
                     AIKNNIFGTLNIAGLSSKYRAKKFVLISTDKAVNPTNIMGATKRAAEMIIQTMNAESQ
                     TEFVAVRFGNVLGSNGSVIPLFKKQIEDGGPVTVTHPDIIRYFMTIPEAVGLVIQAGA
                     MAKGGEIFVLDMGEPVRILDLAKNLIKFSGFEPDVDIKIEFSGLRPGEKLYEELLMSE
                     EGLLDTEHKKIFIGRPIDVDREKITKYLKLLREITNNEEVEKIDGIMRELVPTYIKPE
                     DANIKEIATTREK"
     gene            complement(6615..7706)
                     /locus_tag="JAM15_12780"
     CDS             complement(6615..7706)
                     /locus_tag="JAM15_12780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAT6799127.1"
                     /translation="MKTVCYLADGSNPHTLKWCSFFKNKGYDIHVISLNGGHMEGIKI
                     YNFGSNVEELKNENISKKTGYLGSIKQIKKLVNEIKPDILHAQYASSYGFIGSLLGYH
                     PYIISVWGTDIYDFPNNGFIQKQIIKHNFRKADYIFSNSRDMAKEANKYTAKHVDVTF
                     FGVDMDRFKPMEVEKEDAFVIGIIKSLEKKYGIEYLIQAFKMLKDEYKDKKIILKIGG
                     SGSQMDNLINLAKELGIENDVQFLGRISPENVSKTFNSFDVTVFPSLREGFGVAAIES
                     EACEVPVIVTNVGGHPESVWENETGLIVEPKQAEEIKNAIIKLMENDELRLNMGKKGR
                     QFVRENYEVNLNFNDIEKIYDSIFDKYKK"
     gene            complement(7712..9007)
                     /locus_tag="JAM15_12785"
     CDS             complement(7712..9007)
                     /locus_tag="JAM15_12785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002842842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /protein_id="HAT6799128.1"
                     /translation="MKIAIAGTGYVGLVTGVCLAEVGNENVVCVDVDEQKVKSMKLGI
                     APIYEEGLEELMVKNYNRGRIDYTTDYKKAYEDVDVILIAVGTPERSDGSANLDYIKA
                     VAKQIAETVTKDTLVVIKSTVPIGTNEEIEDYINRNLKNNVKVELASNPEFLSQGTAV
                     KDTLYASRIVIGVESEWAREILEEIYKPFNQPIIVTNRNSAEMIKYASNNFLALKISF
                     MNDIANLCEIAGANIEDVALGMSYDDRIGSKFLKAGIGYGGSCFPKDTKALHWLSEHN
                     GYELKTVKAAIEVNESQKLKLVRKASKLVESFQDMKVAVLGLTFKPDTDDIREAPSIP
                     NIKYLLERGARVTVYDPIGVNNTKKIFGDSILYADSVDDAIEDAEICFIMTEWKDVLN
                     YDIHKYKEKMKNPLVLDGRNCYKIKDMEELGIEYYSIGR"
     gene            complement(9033..9785)
                     /locus_tag="JAM15_12790"
     CDS             complement(9033..9785)
                     /locus_tag="JAM15_12790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAT6799129.1"
                     /translation="MNEPLVSIITPVYNSEEFLSETIKSIQNQTYKNWQLLLVDDCSK
                     DNSSEIIKSFRKEDARIKYIKLEKNSGAAVSRNVGIKNAEGRFIAFVDSDDLWDSRKL
                     EIQIEYMLKENVGFSFTSYRYMRQDGSKTNKVARAPKKIDYEGLLRNTIIGCSTVVID
                     KEIVGEFSMPLVRRGQDTATWLQLLKKEKYAYGIQEDLVNYRLVGNSISSNKIKALKR
                     TWNTYRNVENLSLPKSLYVFCFYVFNAIKKRV"
     gene            complement(9833..10741)
                     /locus_tag="JAM15_12795"
     CDS             complement(9833..10741)
                     /locus_tag="JAM15_12795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAT6799130.1"
                     /translation="MYKYKFTVFTPTYNRAHLLENLYNDLKAQTYDFNDFEWLIVDDG
                     SSDSTKELVEKFISENKLNIRYIYKENGGKHTAINLGVKNADGELFFIVDSDDGLIKD
                     SLEIANDEWDSLENKEGFSGVVGLCVYPSGDLIGTEMPEDKKICHFADLYFKYGVKGD
                     KSIVFVTDELIKFPFPERKEVRFLPESVVWNEMSKYYKVICVNKPMIIRDYLDDGLTK
                     NILSKNALRGRALEFLYLINQNTYPISRYPYMWIKNYINLARYSLLSDSHYFGELRKV
                     SDKLLYLALFPLGYYKYIGQRKLVSK"
     gene            complement(10763..11512)
                     /locus_tag="JAM15_12800"
     CDS             complement(10763..11512)
                     /locus_tag="JAM15_12800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAT6799131.1"
                     /translation="MKKNLVSIITPMYNSEKFIEATIKSVLNQTYQEWEMLIIDDCST
                     DNSPNIVKSYMQQDSRIKCIKTETNKGVSNARNLALSKATGQFIAFLDSDDQWNSSKL
                     EKQVNFMLENDYVISFTSYELMDENDKKLNKVIKVPPNVDYRRLLKGNILGCLTVVID
                     KSKLDFEIRMSGVRHEDYVLWLSILKKGHIAHGINEVLALYRKSSNSLSGNKIKAAMW
                     TWNIYRNIEKIPLYKAIYYFINYGINGIKKS"
     gene            complement(11541..12716)
                     /locus_tag="JAM15_12805"
     CDS             complement(11541..12716)
                     /locus_tag="JAM15_12805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphotransferase"
                     /protein_id="HAT6799132.1"
                     /translation="MDKVKFLINMLLAFFIYPFNKHKFNGRDIWLIGGHSGDIYNDNS
                     KFFYEYMLREHNDVETYWVVNKDSKVFDKIPGKKLIRGSVENYLYYYNSKAIVFSHAP
                     SADIAPYNFAVPVLNYFHKKTIKVFLNHGTISFKKRKPMNKKFKNIIDNLYKSYNIVT
                     ASSEFERNVMVNDWGMLDDSVYIIGNARYDNLPTNEVAQTRDILYTPTWRDWIKFSSG
                     KFTDTDYFKNIMNFLNDDKLNKILDEKDINVKIYMHHLMHEFIDDIKENITGKRIVFL
                     DKGVTLANEIRKSAANITDYSSVAIDFLYMNRPILFYQFDLDEYMEKVDSYIDLKSEM
                     FGSLAYNNDEAVNKLIDIIENNFEVMDNQKNERNKFFRYNDNKNCKRIYDCVLSKIK"
     gene            complement(12731..13570)
                     /locus_tag="JAM15_12810"
     CDS             complement(12731..13570)
                     /locus_tag="JAM15_12810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAT6799133.1"
                     /translation="MLISLIMPTLNRYDDIYLLMDSLENQTYKNFELIVVDQNDNSKV
                     KEIVDKYIDKLDIKYIKSSKKGLSYNRNVGIDNAVGQIIGFPDDDCVYENDTLEKVIN
                     FFNKNEDYKIYSCKTMDSNKVDAFKKMYDGTCDITSSNVLDTITSITFFIDFEGKDYT
                     RFDEKLGVGGEFGAGEEIDYVLNLLSLGFKGKYFGNDIIYHPAKKHSKSKEKYQKDYN
                     YGRGFGALCKKEIVYRKNYKFAKVMVSKLVRNIGGLILSSNRDYHSATIKGRINGFRQ
                     YKL"
     gene            complement(13573..14730)
                     /locus_tag="JAM15_12815"
     CDS             complement(13573..14730)
                     /locus_tag="JAM15_12815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide polymerase"
                     /protein_id="HAT6799134.1"
                     /translation="MKTLNDDRNIMIRKYLYIFVLFIILLRKYMISFIDPNIDIGMIK
                     SALFYSSIGILMLLFLFDKRKSITEMVLVGVCVLLYLLNREGAILLIVLLAVSAKQID
                     DKFIVKNYLIISACFLMVAILLFNLFPSLIFNQEVHYRYIEKIDMLVTRMDFGLGNPN
                     SVFYHMVTIYAAYIFLRYKDYNKWDRIILFGSAFFVYQTTYSRTGFFTILAGLIFVEI
                     IRWIDIKKIKGLPMLLKTLPIILTLFSVIIGTVFDKSTLLNRLLASRPKFWHVYLAEK
                     GNFLKPFGNSYSPAIKATNPLDSSYVYIISVLGVVACILFMYLMYKGIESFIEKDKKA
                     YLVALFIFLLYSFAENLLLEASFSFAVVLLIKEVILNDKREIDLWKMKSRR"
     gene            complement(14746..15468)
                     /locus_tag="JAM15_12820"
     CDS             complement(14746..15468)
                     /locus_tag="JAM15_12820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAT6799135.1"
                     /translation="MIPKKIHYVWFGGPKGNIENICINSWKEKLPEYEIVEWNEKNFD
                     IEKEIKGNKFLEECYKRKLWAFISDYTRIKVLYEQGGVYMDTDMQILKDITPLLENNR
                     LICGYEDDREYINGAIIGVEKGHPFLKDLLEYYEKEVLTSSLFTIPKIMTHLMEKNYK
                     KIDPNNYEEGIRVYDKEYFYPFGFKEDFTPECITENTFGIHWWGKSWAKKRNYFLESK
                     HLTGVNKIWKCCKIFASNTLRS"
     gene            complement(15480..16553)
                     /locus_tag="JAM15_12825"
     CDS             complement(15480..16553)
                     /locus_tag="JAM15_12825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanylyltransferase"
                     /protein_id="HAT6799136.1"
                     /translation="MKVYNVIMAGGGGTRFWPLSRQEVPKQLINLSGEDALINETINR
                     IDSLAKKDDLFIVTNEKQLEALKDIVKDKCLDSNILPEPCARNTAAAIGFAAFNIMKK
                     YGDGVMCVYPADHYIKDEKEFKSILEKAIYIAENNDKLVTIGITPTFPSTGYGYINFN
                     RENTIEDVAYEVVEFVEKPNYEIAKEYVNSKKYVWNSGMFVWKVSKILEDFKRYLPKV
                     YEKLEYISKYLGTKEEMEKIKEIYPTIQSISIDYGIMERSNDVIVVPGDFGWNDVGSW
                     DSLGAIYPTDDEGNIKRGENITIDTKNSIIYSDDKLISTIGISDLIVVSTNDAVMVCR
                     KDKAQDVKKIVEQLKEEDRQEYM"
     gene            complement(16575..18281)
                     /locus_tag="JAM15_12830"
     CDS             complement(16575..18281)
                     /locus_tag="JAM15_12830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HAT6799137.1"
                     /translation="MDYKNNYEMWLNSPYFDEQTKNELLSIKDDEKEIQDRFYKNLEF
                     GTGGLRGIIGAGTNRINIYTVRRATLGVLNYIMKTQGEEGKQKGIVIAHDSRYMSREF
                     CIEVAKTLSAYGVKAYIFEELKPTPELSFAVRYLKCAMGIVITASHNPKEYNGYKVYD
                     SDGGQICIDMANDIIAEVNKIDDYSTIKSIDFEEALSKNLITILDNEVDDEFIKAVKK
                     QVLRQNIIDEYGKKLKIIYTPIHGTGNKPVRKVLNECGFENVMVVKEQELPDSNFSTV
                     KYPNPEEKSVFNIAIEMAKNNGTDLIIGTDPDCDRVGIVVKDSSGEYVVLNGNQVGSL
                     LVRYILESLVEENKLPKNNPTIIKTIVTSELGAKIAKAYNVDCLNTLTGFKFIGEKIK
                     AFEESNDRSFIMGYEESYGYLIGTHARDKDGVVSSLMICEMAAYYSSKGMNLYEALID
                     TYNKFGYYKEDLKSVTLKGIDGIKKIKEMMLYFRSVKIDNVADVKVDKILDYKDGVDD
                     LPKSDVLKFLLEDGSWIAIRPSGTEPKIKFYFGANSDNQEDVEFKLNNLISYILNVVD
                     SI"
     gene            complement(18323..19882)
                     /gene="murJ"
                     /locus_tag="JAM15_12835"
     CDS             complement(18323..19882)
                     /gene="murJ"
                     /locus_tag="JAM15_12835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HAT6799138.1"
                     /translation="MSKTAKAALWIMAATMFSKVLGFLRELVLANFYGTGMYADVFVL
                     TLNIPGLIIAVIGSAVATTYIPMYFETKKRLGDEGALKFTNNVLNICYIMAIVIAIIG
                     LLFTEQFVTVFAAGFRNDPAKFQAAILFTKIMISGVLFLSGSKIFSSFLQVNDSFVIP
                     GLIGIPYNIIIIAAIALSAGKNVWILPAGALLAMASQLLFQLPFAFKKSYKYKPYINL
                     KDESIKELVNLVLPMLVGVAVGQLNIFVDRLLATTLGDGKLSALNYANRLNEFVMALF
                     VTSIITVIYPKLAKMSGKDDKEGFISTIVKSSNCIILVVLPISIGAIILAEPLVRILF
                     QRGKFDALSTDLTSIALRLYSLGLLACGVRDVLYRAFYSLSDTKTPMINGSIALIINI
                     VLNLILIRPLGHAGIAISTSTSNIITVILLFISLKKKNGYFGGDKIIKTGLKSLVASG
                     VMAVATLLIYNNLYAFMGSGTIKEIISVGAGVLGGASVYTVLIVLFKVEEMDLAFEFL
                     RKGKQKLLRRR"
     gene            complement(19997..21052)
                     /locus_tag="JAM15_12840"
     CDS             complement(19997..21052)
                     /locus_tag="JAM15_12840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp7"
                     /protein_id="HAT6799139.1"
                     /translation="MIKKISTILSLVLLISISSTIGVFADANPKRELIEGSIPEISTE
                     LNKRAFKDSKEVILVNEESIVDSISATPLAYAKNAPIVVTKSKNLGRVTRNYLKELGP
                     EKVTIVGGLKAVSKDAERNIEKMGIKVERIRGKDRYDTSLKIAREMYRTVGFDEAFLL
                     SSTTGLENAISVYSYAAKSGMPIIWAKDEGFEEQIDFLKGKNLKKIYALGDSKEFIAE
                     IDSNLKNIEGIKQINKSSTNVDLIKKFYDEKDIKKIYTAKLDFGSRSDVNEYISLGVV
                     SAKENMPILICSDNLSRAQDKFLKDSNINDVVEVGYTVGDYSLFKSIFNLTFLSCIVL
                     ILLLLLITFRALRYESK"
     gene            complement(21147..21803)
                     /locus_tag="JAM15_12845"
     CDS             complement(21147..21803)
                     /locus_tag="JAM15_12845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HAT6799140.1"
                     /translation="MPKIKSYPGADKEIASEIDYSIVKGTVLFDLYQRIMDLVLSIIG
                     LVIGLPLIAIFGILIKIEDKGPITYKQERLGKCGRRFYIYKLRSMRTDAEKFGAQWAE
                     KDDPRITKVGKFIRKTRIDEIPQLFNILKGDMGLIGPRPERPNFTVQFNEEIPGFINR
                     LAIKPGLTGWAQVNGGYEITPEEKLKEDIYYIKNRSILLDFKILFKTVKVVLTGDGAR
                     "
     gene            complement(22053..24077)
                     /locus_tag="JAM15_12850"
     CDS             complement(22053..24077)
                     /locus_tag="JAM15_12850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAT6799141.1"
                     /translation="MKKTTKLLATGMLSVAMVAPNVALAAENTTANTESNSDININLQ
                     RKSVVLGSKSNASVKFKEKLNADSITLNFMCYDMPLEATLNYNEKTDSYEGVINYNKD
                     PEYLNVWELQSIKINGKDEQKVLNKEDLESMGLNLKDYDVTQEFIISDANSTKAVNEY
                     MRKTSAPVKKLAGATRFETAVEISKQGWKDGSSKVVIVNGELAADGITATPLASTYDA
                     PILLANKDDIPESTKAELKRLNPSDVIIIGDDGSVSQKAVSQIKSAVNVNVTRIGGVD
                     RHETSLLIAKEIDKYHDVNKIYIANGYAGEYDALNISSKAGEDQQPIILANKDSVPQG
                     TYNWLSSQGLEEAYYIGGSQSLSSKIIDQISKIAKNGTSKNRVSGADRHETNANVIKT
                     FYPDKELSAMLVAKSDIIVDSITAGPLAAKLKAPILITPKTYVSAYHSTNLSEKTAGT
                     VYQIGDGMKDSVINSIASSLSKHNAPTEPDNSGSAAGKTVVIDPGHGGSDSGATSGLN
                     GGAQEKKYTLNTALATTEYLRSKGINVVMTRDTDKTMALGERTALSNTIKPDLFTSIH
                     YNASNGAGNGVEIYYKVKDKNGGTTKTAASNILKRILEKFNMKNRGIKTRTLDNGKDY
                     LYVLRNNNYPAILVECAFIDNKSDMDKLNTAEKVKTMGTQIGIGIEDTVK"
     gene            complement(24331..25389)
                     /locus_tag="JAM15_12855"
     CDS             complement(24331..25389)
                     /locus_tag="JAM15_12855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5009 domain-containing protein"
                     /protein_id="HAT6799142.1"
                     /translation="MIVCNNPGTWMRMYPQLRHAVWHGVTLADFAFPFFVISLGVTIP
                     ISINSKLKNNKSTLSIILSIFKRSILLILFGFFLNYLGNPDLDTVRILGVLQRMGLVY
                     FVTSLVYLLLKKLNVGSTATIITFLCISAVIIVGYYILAKPYGFELEGSLAQLVDLHF
                     FKGHLYKPEFEPDGFLTSIVAISSGMLGCSMGCVLLKENIGEYKKFFKILIMSIILLI
                     GAFIFNQYFPFNKRLWSSSFVLLMAGSYGMLLSIFYFICDIKNKSKIFTPIIALGSSP
                     IFTYMCLEILSHVFWNIPKLTNKVDYPTTLVEWTTYELITPWAGTTWDSLIFSLLYVL
                     FWVIVMSIMYKKKIFIKI"
BASE COUNT         7941 a         4640 c         2762 g        10131 t
ORIGIN      
        1 taaattttct tataaattat atcattgtct tttttttgta actgaaacaa gtattgaata
       61 tatctcaata ctttaatata attaagtgta tgctattaaa aaatatacag gaaaaagaag
      121 aaagaagggg tacttttgtc aaaattaaag aaatttgtta tactactggc tttcttggta
      181 gtaatattcc ctataagtgt ctatggatat ttttattata aattatctgc tattcatgac
      241 tcgagcataa gtagtgattt attggataac aatgaccata aaaatgaaga tgggataatt
      301 aacatactac ttatgggaac agatgctaga ccaaatgaag attcttcaag gtcagatgct
      361 atgatgatac ttactattga taacaaacac aatgatatca aacttacatc attagctcgt
      421 gatagctatg tagacatccc tggtcatggt aaacaaaaac ttactcatgc ttatgcttat
      481 ggacaagctg atttattaat acaaacaatt gaagagaatt ttaatattga tattcaaaat
      541 tatgcttgtg ttaatttcga gtcatttatg tatataattg atgctattgg tggcgttgag
      601 gttactgttg aaaaaggaga aatacgagaa ctaaataaat ttattcctga aacttataaa
      661 tggaataaaa atgatgataa aggtagcata caatacatta gaaactctgg aaagcagact
      721 ctaaatggat atcaggcact atcttttgca cgtatcagac acaacgatac agcctttgct
      781 agagatggca gacagagaca gattatacaa gctataatca agaaaacgga aactttacct
      841 gttactaaat atccaggttt attagatgca gttcttccat atgttaaaac taacatgaag
      901 cctaatgcaa tactttcttt aggagctcaa gttttaaaaa tgggtgactt aaatattaag
      961 caatttgaat ttcctattga tgatgaaatt catagtacag gtggtatata tggaaaagct
     1021 ggatgggttc ttagatttga cccagatact ttagacatat tacacgattt tatatttaat
     1081 gacatagagt ttaaacaata aaaaattcaa cataaagttt attaaaaagt ataagattaa
     1141 ttactaaaaa agaactatat cgcataatta ttttcaagtt gctgtgtaca cttgattaca
     1201 aaatgcatat agttcttttt tattttctaa tttatgatga taattttcat tttaatctac
     1261 atttataaaa tactctgtat tttaaattaa cttttttatt acttaactaa gtttaagaaa
     1321 gtgtttaatg tgttttgatt tataccatct ccagcttcgt atactagagc agttttctta
     1381 ggctctaaag cagttttctg agcagatgtt acactatttc caagcataac tactggtgat
     1441 tttaatttag ctgctaaagg acctgatgtt aatgcatcta ccaattgatt acttttactt
     1501 acaaacattg atgaatattc agcatttgga tagaattttt gtattacttt tccatttgtt
     1561 tcttctctat tttctccagc tattctattt ttagatacat catttgtaat gaccttatcc
     1621 agcttattta ttactgaatc agatatactt agattaccac ctataaaata agcatctttt
     1681 acttttaaat ctgatatcca attgtaaact tcatcactta cattatcttt tgatactagt
     1741 actattggtt gcttttcttc tcctgctttt gaagctatag aaagagaatc tgcttcacct
     1801 gtaccacttg ttatatatag tttttctact ggattggttt ttactaattc ttttgctatc
     1861 attaaagatg tactatatct atctgaacca ccaactctat ttattgatac atttgacaat
     1921 gtatctttta tctcactctc aactttatct ccaatagagt tatttcctcc aattaaaata
     1981 actttacttg gattaagtct ttttaactca ttcttagtgg atgtaggtat attatcctta
     2041 tttaccaata gtataggagc atcatttgat gtagcaagtg gtgttgatgt tataccatca
     2101 actatagagt acccatttac taatactact gtatctgaat ttgtagccca acctttttta
     2161 cttattgcta ctgctgtgtc atatctttcg tcgcctctta atttctccac tttaacatta
     2221 gatggtggag taactggttc ttcactacta gaatataaac tctttaaatc cttttgtata
     2281 gaagtactat ttgctatatc tttagctgag aaatacatac taccttttat ttcactatac
     2341 tttctattta atgttacttg ttgtactatt tcttttgcta tattttgtcc accataacta
     2401 gattgacctt gcttatatat accttgtcct atgtataagt ctacatttgt tccttttact
     2461 tcattagccc accatgccac taatttagaa taatctgctg ctttaagacc aattggccag
     2521 taaagttgtg gaactacata gtcaatcaat ccttgtttta tccatgctct tgtatctgca
     2581 tatgtaccta cataactttc attacctgat gtatctgaac ctgttgggtc actactctta
     2641 tttctccata tacctgctgg gcttacacca aatacaacat taggctttat actctttata
     2701 gacgctttta catctctaag tagagtattt acattttctc ttctccaatt atccttattt
     2761 tgtccttttc catatttttg gtatgttgca gtatcattga aacttactcc tggatagaag
     2821 taatcatcaa aatgaactcc atctatatcg taattttgaa ctacttctgc tatactatcc
     2881 actatgtact ttctaacttc tggtaaacct gggtcgtagt aatacttatt tccatgttta
     2941 actacccagc ttggattttt ctttgctgga tggtttgctg gcaatttatc tatgctctca
     3001 tctgccatag ttattctata tggattaaac catgcatgaa attccattcc tcttttatgt
     3061 gcttcttcta ttaaaaatgg taatgggtca tatccagggt ctttaccttg tgtaccggta
     3121 agatattcag accatgggtt tatatttgat ttatataaag catctgattt tggtcttact
     3181 tgaaccactg ctgtatttat tcctacactt tttagtttgt ccaataaatc tgtgtattcc
     3241 tttttttgct tggcttcatt attcttagtc ttaggccagt ctaaattata aactgtagat
     3301 atccaagcag ctctcatttc cttatcattt gatgaatcgg caaatgaact tacactacac
     3361 atagtaagtg tcattatcaa tgataatact aatatactta tttttttcat ttcatccccc
     3421 ttaatttttt aaatttattt tttctacaat atacttctta ttaagtatat ctaaaattca
     3481 tattatctgt caaatattga ataatatagt taaaatttat atttgatatt tgattataat
     3541 atgaaataat ttattataaa aaaaacagca aagaaattta tcttctttgc tgtttttata
     3601 acgttcatca ctattttaat attactaaac tcttaaatct ctatgtaaaa cattaaatgt
     3661 aattatatat ttaatgttaa tattcaatcc tatgtaaatc aatatctatt attattgtaa
     3721 aacacgtgta gcagttataa gtcttcttgc ataattagtt cctggagcca tgctagtaac
     3781 ttttactaca tctcctgttt gtggtgaatg tatgaattta gaatctccta catacaatcc
     3841 aacatgattt attgaaccac ctgaaccaaa gaaaactaaa tctcctggtt ttaattctgc
     3901 tcttgatact ttctttccta ctgttgcttg tgatcttgat actcttggta aattaacccc
     3961 tgctccattt ttatagacat aagaagtgaa cccagaacaa tcaaaagcat ttggtccagt
     4021 tgctccccat ctatatggct taccttgttg cttaaatgct aagtttaaaa cattttgtac
     4081 ctttgcatct acatttccac cttgaatagt taaataatct ccatttaccc atcctgtaac
     4141 attgtcaaca ctttttattt taatccatcc atttgaatgt aattctaaaa cttcaacttt
     4201 gtctcctgtg tttatctttc ctactactgc atcatttgca ctagctccac ttcttacatt
     4261 taaaaaatca cactggtcta ctgttgcact cataggtgaa ttagttggct ctgctgcact
     4321 agccgttatt gctcctgctt ctactgtgac aactcctgct attaacacca tagctataaa
     4381 ttttttcaat atatgttttt tatttttaat attcatcata atctcaaata cctaatcctt
     4441 tcgaaaattt aacattttgt tccttcgttt ccaattccta attaacattc tatcttacat
     4501 caaaataaat tgcaaccttt tttgtaatct ttttgtaatc tttttgtaat cttttgtttc
     4561 tttttagtat atatttgttt ctttttgctc cccctggtta caaattagaa atatattcta
     4621 cttttctcta gttgttgcaa tttctttgat attagcatct tctggtttaa tataagttgg
     4681 cactaattcc ctcataatac catctatttt ttcaacctct tcattgttag taatttctct
     4741 taaaagtttt aagtattttg ttattttttc tctatcaaca tctattggtc taccaataaa
     4801 aatcttttta tgctctgtat ccaacagacc ttcttctgac ataagtagtt cttcatacaa
     4861 cttttctcct ggtctaagac cagaaaattc aatttttata tcaacatctg gctcaaatcc
     4921 actgaattta attaagtttt ttgctaaatc caatattctt acaggttctc ccatatcaag
     4981 cacaaatatt tctccacctt tagccatagc cccagcttgt ataactaagc ctactgcttc
     5041 tggtattgtc ataaaatatc taatgatatc tggatgagta actgtcactg gtccgccatc
     5101 ttcaatttgc ttcttaaaaa gtggaattac actaccatta ctaccaagca catttccaaa
     5161 tctaacagca acaaattcag tctggctttc agcattcata gtctgtataa tcatttcagc
     5221 agctctttta gtagctccca ttatgttagt agggtttaca gccttatctg tagatataag
     5281 gacaaatttc ttagctctat attttgaaga caagccagct atgtttaaag ttccaaatat
     5341 attattcttt atagcttcgc cagggctcga ttccataaga ggaacatgtt tatgcgctgc
     5401 tgcatgaaat accacttctg gtttatattt attaaatatt tcatccattc ttttttcttc
     5461 tcttattgat gctattactg tctttaaatc taatttattt ttatattttc taagtaattc
     5521 ttgttgtatt gagtaagcat tattttcata attatcaact ataataagct ctttaggatt
     5581 aaatcctgca atctgtctgc aaagctctga accaattgag cctcctcctc cagttattag
     5641 gattactttt ccctcaatgt aattacttat ctctcttaaa tttgttttta taggctctct
     5701 acccaacaag tcttctatct ctacttctct aatctgtttt atatcaactt ttccatctat
     5761 aatttcgtaa attcctggta ttgtctttat tttacagtta gtgtttttac atatatcaat
     5821 aatctctttt tttctacgtt tctctatgtt tgctattgaa aagattatct catctacatt
     5881 gtacttttct accacatctt ttatatccga agttgttcct acaattttca cattatggat
     5941 tattcttcca attttatttt tatcatcatc aattatagcc actgctactt ttttaagttc
     6001 tgaatttctt tttagttcct gtataaccat ttctcctgca tctcctgcac caattataag
     6061 gatatttgaa acctttcctc tagaatatgt cttgttcatg actattctta tagctctata
     6121 ggctattctt gcgccacttg taaacattat aataaatatt gtatttaata cataaaacat
     6181 tataggataa tcaaacccta ataatttatt tattatataa atcggaatta aataagctaa
     6241 agttgccaca aaaatagata taatttcttc ttctcctgca tatctccata atgtgttgta
     6301 gcacttaaac aatctaaatg atactatatg aagtactata tatatacaca ctgaaattat
     6361 tatatcatta gtggtaaatg catttaaatt acctgtcaag cttaaagaca ttcgaaacgc
     6421 tactagtacg ctacaaatat ctagaattaa tagtgttaaa tgtctaaatt tatatttttt
     6481 aaaaagccta ttaaaaaagc tttctttctc taaatctata ctttctcgca taactagaag
     6541 ccctccttta aacagcaaaa gctacgcacc taagcatagc caacaacatc tatcttttgc
     6601 tgtatttttt cattttattt tttatattta tcaaatatag aatcataaat tttttctata
     6661 tcattaaagt ttaaattaac ctcataattt tctctaacaa attgacgccc tttcttaccc
     6721 atattaagtc taagttcatc attttccatt agttttatta tagcattttt tatttcttct
     6781 gcttgttttg gttctacaat taagccagtt tcattttccc atacagattc tggatgtcct
     6841 cctacatttg taactataac aggtacttca catgcttctg attctatagc tgccactcca
     6901 aatccctctc ttaaagaagg aaatacagtt acatcaaaag aattaaaagt cttgcttaca
     6961 ttttctggag atattcttcc taaaaactga acatcatttt ctatacccaa ttctttagct
     7021 aaatttatta ggttgtccat ctgacttcca gagccaccta ttttaagaat tattttctta
     7081 tctttatatt catctttaag catcttaaat gcttgtatta aatattctat tccatatttt
     7141 ttttctaaac tctttataat tcctattaca aaagcgtctt ctttttctac ttccataggc
     7201 ttaaacctat ccatatctac tccaaaaaag gttacatcta catgtttagc tgtatattta
     7261 ttagcctctt tagccatatc tctactattt gaaaagatat agtctgcttt tctaaagtta
     7321 tgttttataa tttgtttttg tataaaacca ttattaggga aatcataaat atcagtaccc
     7381 caaacagaaa taatatatgg atgataccca agtagacttc ctataaatcc ataactactt
     7441 gcatactgtg catgcaatat atctggcttt atttcattta ctagcttctt tatctgcttt
     7501 attgaaccta agtatcccgt ttttttagaa atattttcat tttttagttc ttctacatta
     7561 gaaccaaaat tataaatttt tattccttcc atgtgacctc catttaaaga gattacatga
     7621 atgtcatatc ctttattttt aaaaaaacta caccatttta aagtatgagg atttgaccca
     7681 tcagctaaat aacaaacagt cttcataata tttaccttcc tatcgaataa tactcaattc
     7741 ctaactcttc catatcttta attttataac aatttcttcc atcaaggact aaaggatttt
     7801 tcatcttttc cttatactta tgtatatcat aatttaatac atctttccat tctgtcatta
     7861 taaaacatat ctctgcatct tctatcgcat catctacaga atcagcataa agtatagagt
     7921 caccaaatat tttcttagta ttatttacac caattgggtc gtatacagta actcttgccc
     7981 ctctttcaag caaatatttt atatttggta tagatggtgc ttctcttata tcatcagtgt
     8041 ctggtttaaa agtcaaacct aaaacagcaa ccttcatatc ttgaaagctc tctactaact
     8101 tagatgcctt tctaactaat ttaagttttt gactttcatt aacttctatt gcagctttta
     8161 ctgtttttaa ttcataacca ttatgttcag ataaccagtg aagagctttt gtgtcttttg
     8221 gaaagcaaga accgccatac cctattcccg cctttaaaaa cttacttcct attctatcat
     8281 cataactcat tcctaaagct acatcttcta tgttagctcc tgctatttca caaagatttg
     8341 caatatcatt cataaatgat attttaagag ctaagaagtt atttgatgcg tattttatca
     8401 tctcagcact atttctattt gtaactatta taggttgatt aaaaggctta tagatttctt
     8461 ctaatatttc tctagcccat tcactttcta cacctataac aattcttgaa gcatatagag
     8521 tatcttttac tgctgttcct tgtgataaaa actctggatt agatgcaagc tctactttta
     8581 cattattttt taggtttcta tttatataat cttctatctc ttcatttgta ccaattggaa
     8641 ctgtagattt tattactact agagtatctt ttgtcacagt ttcagctatt tgctttgcaa
     8701 ctgcctttat ataatctagg ttggctgagc catcacttct ctcaggtgta cctacagcta
     8761 ttaatattac atctacatct tcataagctt ttttatagtc tgtagtgtaa tctattcttc
     8821 ctctgttgta atttttaacc ataagttctt ctaggccttc ttcatatata ggtgctattc
     8881 caagtttcat tgatttaact ttttgttcat ctacatcaac acagactaca ttttcattgc
     8941 ctacctctgc tagacaaaca cctgtaacca aacctacata tcccgtccca gctatagcta
     9001 ttttcatttt tttacctcca agtatataaa acttatactc tttttttaat ggcattaaaa
     9061 acatagaaac aaaatacata tagacttttt ggtaaactta aattttcaac atttctataa
     9121 gtattccaag ttcgttttaa tgcttttatc ttgttacttg atatagaatt tccaactaat
     9181 ctgtaattca ctaaatcttc ctgaatccca tatgcatatt tttccttttt aagtaactgt
     9241 aaccaggtcg cagtatcttg tcctcttctt accaaaggca tgctgaactc tcctacaatc
     9301 tccttatcaa tgaccactgt agaacatcct attatagtat ttctaagtaa tccttcatag
     9361 tcaattttct taggagctct tgcaacctta ttcgtttttg acccatcttg tctcatatat
     9421 ctataagatg taaaagaaaa acctacattt tcttttaaca tatattctat ctgaatctct
     9481 aattttctac tatcccataa atcatcacta tctacaaatg caataaatcg accttccgca
     9541 ttcttaatac caacatttct agatactgca gctccagaat ttttttcaag ctttatatat
     9601 tttattctag catcttcttt tcgaaaactt tttataattt cacttgaatt gtccttagaa
     9661 caatcatcca ctaataaaag ctgccaattt ttataagttt gattttggat tgactttatc
     9721 gtctctgata aaaactcttc tgaattataa acaggagtaa ttatcgatac taaaggctca
     9781 ttcatatttt tactctcctt atatagcaac tagcagtact ataccaacaa gtttacttag
     9841 atactaattt tctttgtcca atatatttgt aatatcctaa tgggaataat gctaaataca
     9901 acaatttatc agatactttt cttaattcac caaaataatg actatcagac aacaatgagt
     9961 atctggctaa atttatgtaa ttttttatcc acatatatgg atatctactt attggatatg
    10021 tattttgatt tattaaatat aaaaactcta atgctctacc tcttaatgca tttttactta
    10081 atatattctt agtcaaacca tcatccaaat aatctcttat tatcataggt ttatttacac
    10141 atataacttt atagtattta gacatttcat tccatactac actttctggt aaaaatctca
    10201 cttcttttct ttctggaaaa ggaaatttta taagctcatc agttacaaat actatgcttt
    10261 tatctccctt aacgccatac ttaaaatata ggtctgcaaa gtgacatatt ttcttatctt
    10321 caggcatttc tgtccctatc aaatctccac ttggatatac acaaagtcca acaactccac
    10381 taaatccttc tttattctct aaagaatccc actcatcatt agcaatttca agagaatctt
    10441 taattaaacc atcatcacta tctacaatga aaaatagctc tccatctgca ttttttacac
    10501 ctagatttat tgcagtatgt tttcctccat tttctttgta tatatatctt atatttaatt
    10561 tattttctga tataaatttt tcaactaact ctttagtact gtcgctactt ccatcatcaa
    10621 caatcaacca ttcaaaatca ttgaaatcgt aagtttgagc ttttaaatca ttgtacaaat
    10681 tttcaagtaa atgagctctg ttatacgtcg gagtaaatac agtaaattta tatttataca
    10741 ttaattaaat cttcctctct gtctaacttt ttttgattcc gtttattcca taattaataa
    10801 agtagtatat agctttgtat aaaggtattt tttctatatt tctatatata ttccaagtcc
    10861 acatagcagc ttttatttta ttaccactta gggaattgct agattttcta tataatgcta
    10921 gaacttcatt tattccatga gcaatatgcc cttttttcaa tatcgataac cataaaacat
    10981 aatcttcatg tcttacacca ctcattctta tttcaaaatc caatttagac ttatcaatca
    11041 caacagtaag acatcctaag atatttcctt ttaataatct tctataatct acattaggtg
    11101 gaacttttat tactttgttt aattttttat cattttcatc catcagttca tatgaagtaa
    11161 atgaaattac atagtcattt tctaacataa aatttacttg tttttctaac ttactgctat
    11221 tccattggtc atcactatct aaaaaagcta taaattgtcc tgttgcctta cttagtgcta
    11281 aatttctagc attagagaca cccttattag tctcagtctt tatacatttt attctactat
    11341 cctgttgcat ataagatttg actatattag gactattatc tgttgagcaa tcatcaataa
    11401 ttaacatttc ccattcttga taagtttggt ttaatactga ttttatggtt gcttcaataa
    11461 atttttcaga attatacatg ggagtaatta tagatactaa attcttcttc atattacctt
    11521 cctcatcatt tataaaatat ttatttaatt ttacttaata cacaatcata tatcctcttg
    11581 cagttcttat tatcattata tctgaaaaac ttatttcttt catttttttg gttatccata
    11641 acctcaaaat tattttcaat aatatcaata agtttattca cggcttcatc attattataa
    11701 gccaaagacc caaacatttc actttttaaa tctatatatg aatcaacttt ttccatatat
    11761 tcatccaaat cgaattggta aaacaagata ggtctattca tatacaaaaa gtctatggct
    11821 acacttgaat aatcagttat atttgcagct gattttctga tttcatttgc tagagttacc
    11881 cctttatcta aaaacacaat tcgttttcct gttatatttt cttttatatc atctataaac
    11941 tcatgcataa gatgatgcat ataaattttt acatttatat ctttctcatc taatatttta
    12001 tttaatttgt catcatttaa aaaattcatt atatttttaa aataatctgt atccgtaaat
    12061 tttcctgaac taaattttat ccaatctctc catgtaggag tatataatat atctcgagtt
    12121 tgtgcaactt catttgttgg taaattgtca tatcttgcat ttccaattat ataaactgag
    12181 tcatctaaca ttccccaatc atttaccata acatttcttt caaattcaga acttgctgta
    12241 actatattat agcttttata taggttatct ataatatttt tgaacttctt gttcataggt
    12301 tttctttttt taaagcttat agtcccatga tttaaaaaca cttttatcgt ttttttatga
    12361 aaataattaa gaacaggtac agcaaaattg tatggtgcta tatctgctga tggtgcatgt
    12421 gaaaatacta tagcttttga attgtaataa tacagatagt tttctacact tcctcttatt
    12481 aattttttgc ctggaatttt atcaaatact ttactgtctt tatttactac ccaataagtt
    12541 tctacatcat tatgttctct tagcatatac tcataaaaaa actttgaatt atcattgtat
    12601 atatcccctg aatgtccacc tataagccag atatctctac cattaaactt atgcttatta
    12661 aatggatata taaaaaaagc caaaagcata tttattaaaa atttaacctt gtccataaac
    12721 accatcctca ttataacttg tactgtctaa atccattaat tcttcctttt atagtggcac
    12781 tatgataatc tctattggaa ctcaatataa gaccccctat atttcttaca agttttgata
    12841 ccataacttt tgcaaactta taattttttc tatagactat ttcctttttg caaagcgctc
    12901 caaagcctct tccataatta taatcttttt gatacttttc tttagattta gaatgttttt
    12961 ttgcaggatg gtaaattata tcatttccaa agtattttcc tttaaaacct aaactcaata
    13021 agtttaaaac ataatctatc tcttcaccag caccaaactc tccaccaaca cccaattttt
    13081 catcaaatct tgtatagtct ttaccttcaa aatcaataaa aaaagttatg gatgttatag
    13141 tatccaaaac gttggaactt gtgatatcac aagttccatc atacattttc ttaaatgcat
    13201 caactttatt tgaatccata gttttgcaac tgtatatttt ataatcttca tttttattaa
    13261 agaaatttat aactttttct aatgtatcat tttcgtagac acaatcatca tcagggaaac
    13321 ctataatttg ccctacagca ttgtctatgc ctacatttct gttataactc aatccttttt
    13381 tagagctttt tatatacttt atatctaact tatcaatgta tttatcaact atttctttaa
    13441 ctttgctatt atcattttgg tctactacta taagttcaaa gtttttgtaa gtttgatttt
    13501 ctaagctatc cataagtaag tatatatcat catatctatt taatgttggc attattaatg
    13561 atattaacat tactacctcc tacttttcat cttccacaaa tctatttccc ttttatcatt
    13621 taatatcact tcttttatta gtaatactac tgcaaaacta aatgaagctt ctaataataa
    13681 attttctgca aaagagtata gtaaaaatat aaataaagct actaaatatg cttttttatc
    13741 tttttctata aagctttcta ttcctttata catcaaatac ataaataata tacaagcaac
    13801 tactcctagt acactaatta tatatacata agaactatct aatggattag ttgcttttat
    13861 agcaggacta tatgaatttc caaaaggttt tagaaaattc cccttttcag ccaagtatac
    13921 atgccagaac ttaggtctac ttgctaataa tctatttaat aaagtgcttt tatcaaatac
    13981 tgtaccaata attacactaa atagagtaag tattattggt aatgtcttta ggagcattgg
    14041 cagtcctttt atttttttta tatctatcca tcttattatt tctacaaata ttaatcctgc
    14101 taatatagtg aaaaatccag ttctactata tgtggtttga taaacaaaaa atgcagaacc
    14161 aaataaaatt attctatccc atttattata atctttatat cttaagaata tatatgctgc
    14221 atatatagta accatatgat aaaatacact atttggatta ccaagtccaa aatccattct
    14281 tgtaacaagc atatctattt tttctatata tctatagtgg acttcctgat taaatattaa
    14341 tgaaggaaat aaattaaata ataatatagc taccattaaa aaacatgccg atattattaa
    14401 ataattttta actataaatt tatcatctat ttgcttagct gatacagcta ataaaacgat
    14461 taataatata gctccttccc tatttaataa ataaagtaag acacaaactc caactagtac
    14521 catttctgtt atactttttc tcttatcaaa taaaaaaagt agcattagta ttcctattga
    14581 agaataaaat aacgctgatt taatcatccc tatatctata tttgggtcaa taaatgatat
    14641 catatacttt ctaagtaata tgataaacaa aacaaatata taaagatatt ttctaatcat
    14701 aatatttcta tcatcattta aagtcttcat tttactttct cccttttagc ttcgtaaagt
    14761 attacttgca aatattttac aacacttcca tatcttattt acacctgtta agtgtttgct
    14821 ttctaagaaa taatttctct ttttagccca actttttccc caccaatgta tcccaaaagt
    14881 gttttctgtt atacattctg gtgtaaagtc ttctttaaat ccaaaaggat aaaaatattc
    14941 tttgtcgtaa acacgtattc cttcttcata attatttggg tcaatcttct tataattctt
    15001 ttccataaga tgagtcatta tttttggtat tgtaaacaat gaagaagtaa gtacttcttt
    15061 ttcataatac tccaataagt cttttaaaaa aggatgtcct ttttctacac ctattatagc
    15121 accatttata tactctctat catcttcata cccacagatt agcctattat tttctaaaag
    15181 aggagttata tcctttaata tttgcatatc tgtatccata taaactccac cttgttcata
    15241 gagtactttt attcttgtat aatcagatat gaatgcccaa agttttcttt tataacattc
    15301 ttccaaaaac ttatttcctt ttatttcttt ctctatatca aagttttttt cattccactc
    15361 tactatctca tattctggaa gcttttcttt ccaagaattt atacatatat tttctatatt
    15421 tccttttgga ccaccaaacc atacataatg tattttttta ggaatcaaat gaacacctcc
    15481 tacatatatt cttgtctatc ttcttctttt aactgttcta ctattttttt gacatcttga
    15541 gctttatctt ttctacaaac cataactgca tcattcgtag atactactat caaatcacta
    15601 atacctattg ttgatattaa tttgtcatct gaatatataa ttgaattttt agtatctata
    15661 gtaatatttt cacctctttt gatgttacct tcatcatcag ttggatatat tgcacctaga
    15721 gaatcccaag aaccaacatc attccatcca aaatcaccag gaactactat aacatcatta
    15781 cttctttcca taataccata atctatagag attgattgta tagttgggta tatttctttt
    15841 attttttcca tttcttcttt tgttcctaag tatttactta tatattctaa tttttcatat
    15901 acttttggca agtatctctt aaaatcttct aatattttag ataccttcca tacgaacatt
    15961 ccactattcc atacatactt tttagagttt acatattctt tagcaatttc atagtttggt
    16021 ttttctacaa actccactac ctcatatgca acatcttcta tcgtattttc tctattaaaa
    16081 tttatgtatc catatcctgt tgatggaaat gtaggagtta tcccaatagt tactagttta
    16141 tcattatttt ctgctatata gatagctttt tccaaaatag atttaaattc tttttcatct
    16201 tttatataat ggtcagctgg atatacacac ataacaccat caccatattt tttcattatg
    16261 ttaaatgctg caaagcctat agctgctgct gtatttctgg cacatggctc tggcaatata
    16321 ttactatcca aacatttatc ttttactata tcctttaaag cttccaattg cttctcattg
    16381 gttactataa ataaatcatc tttttttgct agagaatcta ttctgtttat agtttcgttt
    16441 attaaagcat cttctccact taaatttata agctgtttag gtacttcttg tctactaagt
    16501 ggccagaaac gagttcctcc tcctccagcc attatgacat tgtatacttt cattatttat
    16561 ctccccttag ctttttatat agaatccact acatttaata tataagatat taaattgttc
    16621 aacttaaatt ctacatcttc ttgattgtct gaatttgctc caaagtaaaa tttaatttta
    16681 ggttctgtac ctgaaggtct tatagctatc caagagccat cttcaagtaa aaatttaagt
    16741 acatctgact taggtaaatc atcaacacca tctttatagt ctaaaatttt atctactttt
    16801 acatcagcca cattatctat tttaacactt ctaaagtaaa gcatcatctc ttttattttt
    16861 tttattccat ctataccttt taaagttact gactttaagt cctctttgta gtatccaaat
    16921 ttattatatg tatctatcaa agcttcatac aagttcatac cttttgaaga atagtatgct
    16981 gccatttcac atatcataag tgaagataca acaccatctt tatctctagc atgagttcca
    17041 attaagtaac catagctttc ctcatatccc attataaaac ttctatcatt gctttcttca
    17101 aacgctttta ttttttctcc tataaattta aatcctgtta aagtatttaa acaatctaca
    17161 ttataagcct ttgctatttt tgcacctagt tctgatgtaa ctatagtttt tattattgta
    17221 ggattgtttt taggaagttt attttcttca actaaactct ctaatatata tctaactaaa
    17281 agtgaaccga cttgatttcc atttaagact acatattcac cacttgaatc ttttacaacg
    17341 atacctactc tatcacaatc agggtctgtt cctattatca aatcagtgcc attattcttt
    17401 gccatttcaa tagctatatt aaacactgac ttttcttcag gattaggata ctttactgtt
    17461 gaaaaattag aatctggtaa ttcttgctcc ttaactacca ttacattttc aaaaccacat
    17521 tcatttaaga cttttcttac tggtttattt cctgtaccat gaataggtgt atatattatt
    17581 tttaattttt tcccgtattc atctattata ttttgtctta aaacttgctt cttaacagct
    17641 tttataaact catcatctac ttcattatct aatatagtta ttaaattttt agataaagct
    17701 tcttcaaaat ctatactttt aatagtgctg taatcatcaa tcttattaac ttctgctatt
    17761 atatcatttg ccatatctat acagatttga ccaccatctg agtcatatac tttatatcca
    17821 ttgtattctt taggattatg acttgctgtt attactattc ccatagcaca ctttaaatat
    17881 ctaacagcaa aagaaagttc tggtgtaggc tttaattctt caaaaatata agcctttaca
    17941 ccataagcac ttaaagtctt tgctacttct atacaaaact ccctagacat gtatctacta
    18001 tcatgtgcta taactattcc cttttgttta ccttcttctc cttgagtctt catgatataa
    18061 tttaaaacgc ccagtgtcgc acgtctaaca gtataaatat tgattctatt agttcccgct
    18121 cctattatac ctcttaaacc acctgttcca aactctaaat tcttatagaa tctatcttgt
    18181 atttcttttt catcatcttt tatgcttaat agctcatttt ttgtttgctc atcaaaataa
    18241 ggagaattta accacatctc ataattattc ttataatcca tattttcatc ctttctgact
    18301 ctaatttaaa atttcaaggt aattatcttc ttctaagtag tttttgtttt ccttttctta
    18361 aaaattcaaa agctaagtcc atctcttcta ccttaaataa aactatcaat acagtatata
    18421 cagaagctcc acctaatact ccagctccaa ctgatataat ttctttaatt gttcctgaac
    18481 ccataaatgc atatagatta ttatatatca ataaagtagc tactgccatc acaccagatg
    18541 ctaccaaact ttttagacca gtctttataa ttttatcccc tccaaaatat ccatttttct
    18601 ttttaagaga tataaataac aatataactg taattatatt ggatgtacta gttgatatag
    18661 caatacctgc atgacctaat ggtcttatca atattaaatt aagaactata tttattatta
    18721 aagctatact tccatttatc attggcgttt ttgtatctga aagagagtaa aatgccctat
    18781 ataagacatc tcttactcca caagccaata aacctagtga atataatcta agcgctatag
    18841 atgtaagatc tgttgataac gcatcaaatt tacccctttg aaataatatc ctaacaagag
    18901 gctctgctaa tataatagct cctatagata taggaagcac caccaatata atacaatttg
    18961 aagattttac aatagtactt ataaatcctt ctttatcatc tttaccagac atttttgcta
    19021 gcttaggata tataactgtt attatagatg taacaaataa tgccataaca aactcattta
    19081 gcctatttgc atagttaaga gcagacaact ttccatcacc caaagtagtt gccaataatc
    19141 tgtcaacaaa tatatttaac tgtccaacag ctactcctac caacataggc aatactaggt
    19201 ttactaattc ttttatagac tcatccttta agtttatata tggcttatac ttgtaggact
    19261 tcttaaatgc aaatggcagt tgaaataata gttgactcgc catagccaat agtgctcctg
    19321 ctggtagtat ccatacgttt ttacctgcac ttagtgctat tgctgctatt attataatat
    19381 tatatgggat tcctataagc ccaggaatta caaaactgtc attcacctgt aaaaacgaac
    19441 taaatatctt acttccactt aggaataaaa ctcctgaaat cattatttta gtaaataata
    19501 ttgctgcttg gaacttagca gggtcgtttc taaatcctgc tgcaaatact gtaacaaatt
    19561 gctctgtaaa taaaagccca ataatagcta ttactatagc cattatatag catatattta
    19621 aaacattatt agtaaatttt aaggcacctt catctccgag tcttttcttt gtctcaaagt
    19681 acataggtat ataagttgta gcaactgcag agcctatgac tgctatgatt aaaccaggta
    19741 tatttaatgt taatacaaat acgtctgcat acatacctgt cccatagaaa tttgcaagta
    19801 caagttctct aaggaaacct aatacttttg aaaacatagt ggctgccata atccacaatg
    19861 ctgctttagc tgtttttgac atcttctttc tccttatcta atttaaactc taaaagtaga
    19921 acttttaaaa ctgcttataa acattattct aattaagtaa atttaaccta tgaaaagctt
    19981 ccttataaat taaaaactat ttcgactcat atctaagtgc cctaaatgta atcaatagta
    20041 ataatagtat taatactata caagataaga atgttagatt aaatatgctc ttaaatagac
    20101 tataatcacc tactgtatac ccaacttcaa ctacatcatt tatattgcta tctttcaaga
    20161 atttatcttg tgcacgactt aagttatcac tacaaatcag tattggcata ttttcttttg
    20221 ctgatactac tcccaaagaa atatattcgt ttacatcaga tctgctacca aagtctaatt
    20281 tagcagtata gattttcttt atatcttttt catcataaaa cttctttatt aaatcaacat
    20341 ttgtacttga cttatttatt tgctttattc cttctatatt tttcaagtta gaatcaatct
    20401 ctgcaataaa ttcttttgaa tcacctaatg catatatttt tttaagattc ttacctttta
    20461 agaaatcaat ttgttcctca aacccttcat ctttagccca tattattggc attccacttt
    20521 tagcggcata agaatataca gatatggcat tctctaatcc tgttgttgag ctaagtaaaa
    20581 atgcttcatc aaatcctact gttctataca tttctctagc tatctttaaa gatgtatcat
    20641 atctgtcttt tcctcttatt ctttctactt ttattcccat tttttctata ttacgttcag
    20701 catctttaga tactgccttt aaaccaccta ctatcgtaac cttctctgga cctagttctt
    20761 ttagataatt tcttgttact ctaccaagat ttttactctt agttacaact attggagcat
    20821 tttttgcata tgctaaaggt gttgcactta tactatctac aattgactct tcatttacaa
    20881 gaattacttc tttagaatcc ttaaatgctc ttttatttaa ttctgtcgaa atctctggta
    20941 tactcccttc tatcaactct cttttgggat ttgcatctgc aaatacccct attgtgctag
    21001 aaatagagat taacaaaact aacgataata tagtagaaat ttttttaatc ataagttctc
    21061 attccttttc ttttttgtat tttttgacaa taaaaaagct ctttttaaag agctttttca
    21121 ttgattagta atctaatatt ttaaaattat ctagctccgt ctcctgtcaa tactacttta
    21181 acagttttaa agagtatctt aaagtcaagt aatatactcc tattttttat atagtaaata
    21241 tcttctttaa gtttttcttc aggagtgatt tcgtatccac catttacttg tgcccaacct
    21301 gtaagcccag gttttatagc gagcctgttg ataaatccag gtatttcctc attgaattga
    21361 acagtaaagt tcggtctctc tggcctaggg cctattaagc ccatgtcccc ctttaatata
    21421 ttaaacagct gtggaatctc atcaattcta gttttcctaa taaactttcc aaccttagtt
    21481 attctaggat catctttttc agcccattgt gcgccaaatt tttctgcgtc tgttctcata
    21541 gatcttaatt tatatatata gaatcttctc ccgcattttc ctagtctttc ttgcttataa
    21601 gttattggtc ctttgtcctc tattttaata agaattccaa atattgctat taaaggtaaa
    21661 cctatcacaa gtcctattat agataaaact aaatccataa ttctttggta caagtcgaat
    21721 aaaaccgttc cttttactat gctatagtca atctcacttg caatttcttt atctgcccct
    21781 ggatagcttt taattttagg tatttcacac tcatcattag tatatccaga catagttacc
    21841 tccatattgg aataaaaatt tttttaattc ttaatttcaa cttatttcta tcttattttt
    21901 gacttatttc tatattatac tcaataatga gcagattatc aatacaagaa acatcattgt
    21961 aaacaatttg attctttaca aaaatatatc atctcttgtt atattttaca ttataacagg
    22021 agatgatatg ttttgcttta atatttttta ttttatttta ctgtatcttc tattcctatt
    22081 ccaatttgag ttcccattgt ttttactttt tctgcagtat ttaacttatc catatcgctc
    22141 ttattgtcaa taaatgcaca ttcaacaagt attgctggat aattgttatt tcttaacaca
    22201 tataggtaat cttttccatt atcaagtgtt cttgtcttga ttcctctatt tttcatgtta
    22261 aatttttcta gtattctttt taagatattt gatgctgcag tcttagttgt tccaccattt
    22321 ttatctttta ctttgtaata aatttccaca ccattaccag ctccattaga cgcattgtaa
    22381 tgtatacttg taaataaatc tggctttata gtgtttgata atgctgttct ttctcctaaa
    22441 gccattgttt tgtctgtatc tctagtcata acaacattta taccttttga acgtaaatat
    22501 tcagtagttg ctaatgctgt attaagagta tatttctttt cttgtgctcc accatttaat
    22561 ccacttgttg cccctgaatc agaaccccca tgacctgggt ctatcactac agtttttcct
    22621 gctgctgaac ccgaattatc tggttctgtt ggtgcattgt gttttgataa actagatgct
    22681 atagaattta taacactatc tttcatccca tcaccaattt gatatactgt tcctgctgtt
    22741 ttttctgata agtttgtgct atggtatgca gaaacataag tctttggagt tataagtatt
    22801 ggagctttta atttagctgc taaaggtcct gctgttattg agtcaactat tatgtcagat
    22861 tttgcaacta acattgcact caactcttta tctggataga aagtcttaat tacatttgca
    22921 tttgtttcat gtctatctgc tccagaaact ctattttttg aagtaccatt ttttgctatt
    22981 ttagatattt ggtctataat ttttgatgat aaactttgac taccacctat gtaataagct
    23041 tcttctaaac cttgtgaaga taaccaatta tatgtacctt gtggtacaga gtctttatta
    23101 gctaatatta taggttgttg gtcttctcca gcttttgatg aaatattaag agcatcatat
    23161 tcaccagcat atccatttgc tatgtatatt ttattaacat catgatactt atctatttct
    23221 tttgctataa gtaaagatgt ttcatgtcta tcaactccac caatacgagt tacatttaca
    23281 tttacagcag atttaatttg agacactgcc ttttgtgaaa ctgaaccatc atcacctata
    23341 attattacat cacttggatt tagacgtttt aactctgctt ttgtactttc tggtatatca
    23401 tctttatttg caagtaatat tggtgcatca tatgtagatg caagtggagt agctgtaatt
    23461 ccatctgctg ctaattctcc attaactatt acaaccttac tagacccatc tttccaacct
    23521 tgtttactta tctcaacagc agtttcaaat ctagtagctc cagcaagttt ttttactggt
    23581 gcagaagttt ttctcatata ttcatttact gcttttgttg aatttgcatc acttattata
    23641 aactcttgtg taacatcata atccttaaga tttaatccca tagactctaa gtcttctttg
    23701 tttaaaactt tctgttcatc tttaccattt atttttatgc tttgaagttc ccatacattt
    23761 aagtattctg ggtctttgtt atagtttatt acaccttcat atgaatctgt cttttcattg
    23821 taatttaaag tagcttcaag tggcatatca taacacataa aatttaatgt tattgaatca
    23881 gcatttaatt tttctttaaa ttttacactt gcattagatt tacttcctaa cactacactt
    23941 tttctttgta aatttatatt aatatctgaa ttagattctg tatttgcagt agtattttca
    24001 gccgctaaag ctacgtttgg tgccaccatt gctacagaca acattcctgt tgccaataat
    24061 tttgttgttt ttttcatcat atccccccta attttttggt tctttaaatc tttaaatctt
    24121 ttttaataca tcttaagctt gttttatatt acataaattc aatattatgt aaatcttttt
    24181 tcattatagc acaaaaaatt acaaattgta aactttttgt aatcttttat ggcatggttt
    24241 ttaaatttta tcgaggagaa attttgatta tatttgatag tttccgtata tttgaacaaa
    24301 tcaaagactt tatcatctaa aaatattgca ctaaatttta ataaatattt ttttcttgta
    24361 cattatagac attactataa cccagaatag gacatacaat aaagaaaata taagagaatc
    24421 ccaagttgta cctgcccaag gtgttataag ttcatatgta gtccactcta ccaaagtagt
    24481 tggataatcg actttgtttg taagttttgg aatattccaa aaaacatgac tcaatatctc
    24541 aagacacata tatgtaaaaa tagggctact tccaagtgct attatcgggg taaatatttt
    24601 acttttattt ttgatgtcac atataaaata aaatattgac agtaacatac cataactgcc
    24661 agccattaaa agtacaaatg agctagacca taatctttta ttaaatggaa aatactgatt
    24721 aaagataaaa gcacctatta gtaaaattat gctcataatt aatattttaa agaatttttt
    24781 atattctcct atgttttctt ttaaaagtac acatcccata gagcatccca acatacctga
    24841 agaaattgct actatactag ttaaaaaacc atctggttca aattccggct tgtacaaatg
    24901 tcctttgaag aaatgtaaat ccactaactg tgcaagagaa ccttctagct caaatccata
    24961 aggttttgct aatatgtagt accccactat tataactgca gatatacata gaaaagtaat
    25021 tattgtagca gtacttccaa catttaattt ttttagtagt aaatatacta agctagtcac
    25081 aaaatagact aatcccatac gttgaagtac tccaagtatt cttacagtat ctaaatcagg
    25141 atttcctagg taatttaaga aaaatccaaa taatatcaat aagatacttc tcttgaatat
    25201 actaagtatt atactcagtg tggatttatt attttttagt ttactattta ttgatattgg
    25261 aattgtaaca cctaaagata taacaaaaaa aggaaatgca aaatctgcaa gtgttacacc
    25321 atgccataca gcatgtctta attgaggata cattctcatc caagtcccag gattattgca
    25381 gactatcatg agggctattg atagccctct tattatatct attgatttaa tcctactatt
    25441 cgtaagttta gaatctacag cattatttga aatt
//
LOCUS       DACTZW010000061        25437 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.061, whole genome shotgun sequence.
ACCESSION   DACTZW010000061 DACTZW010000000
VERSION     DACTZW010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25437
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.061"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            559..3201
                     /gene="adhE"
                     /locus_tag="JAM15_12860"
                     /gene_synonym="adhC"
     CDS             559..3201
                     /gene="adhE"
                     /locus_tag="JAM15_12860"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HAT6799143.1"
                     /translation="MEKKEKVVEKSNVEVCSPEIVNSVETLRMRLEEIRLAQKEFATF
                     TQEQVDKIFLAASTAANQQRIPLAKMAVEETGMGIVEDKVIKNHFASEYIYNAYKDTK
                     TCGVIEKDEAFGFTRIAEPVGVLSAVIPTTNPTSTAIFKSLIALKTRNGIIFSPHPRA
                     KNCTIEAARVVHDAAVKAGAPKGLIGWVDVPSIELTNVVMAEADLILATGGPGMVKSA
                     YSSGKPAVGVGPGNVPAIIDESADIKMAVSSILVSKSFDNGMICASEQAVIVPEKIYE
                     EVKKEFKYRGAHFLNKEETEKVGKVVIIDGSLNARIVGQPAHVIAKMADVEVPKTARI
                     IIGEVESVELNEPFAHEKLSPVLAMYKSKSFEDAVAKAEKLVADGGYGHTSSLYADSI
                     NHPERVEKFVNAMKTCRVLVNTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVSENVG
                     VKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVAAREFKDVMDKKKAFIVTDSFLY
                     NNGYTKKLTDLLDEMGIKHTTFFDVAPDPTLACAREGAKAMADFQPDLIIAVGGGSAM
                     DAGKIMWVMYEHPEVDFQDLAMRFMDIRKRVYVFPKMGEKAYFAAIPTSAGTGSEVTP
                     FAVITDQDSGVKYPLADYELMPNMAIIDADMMMEMPPRLTAASGVDALTHALEAYVSM
                     LRTEPADGLALQAGKIIFEYLPRAYKNGKNDKEAREKMAMASTMAGMSFANAFLGICH
                     SLAHKLGAFHHVQHGVANALLINEVIKFNCAEAPNKMGAFSQYRYPDCIQRYAEFASF
                     VGIKGSTDQEKVDNLIKAIDELKAKVGLPKTIKEAGVEESKFLEGLDAMVEQAFDDQC
                     TGANPRYPLMSELKEIYLKVYYGK"
     gene            complement(3561..3902)
                     /locus_tag="JAM15_12865"
     CDS             complement(3561..3902)
                     /locus_tag="JAM15_12865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799144.1"
                     /translation="MLLILGNLNLNLDFDYRIIREENDDVDIFIDINYRSLDIDTDGS
                     NLFNSRIQFPFVRALILRLNKNNQCMTIHLLRDIDLFSAFANFEVDYSDSIINIKNQN
                     EKVILNKSIKK"
     gene            complement(3929..4600)
                     /locus_tag="JAM15_12870"
     CDS             complement(3929..4600)
                     /locus_tag="JAM15_12870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6799145.1"
                     /translation="MPILETINLGKIYGKKETSVHALKNANLKINKGEFVAIIGPSGS
                     GKSTFLHLVGGLERPSNGTIKVDGKDICCLSDKELARYRRQKVGFVFQQYNLIPVLNV
                     KENIELPLKLDNKKIDKEYIDDLINLLGLNERKNHLPNQLSGGQQQRVAIARALSAKP
                     SIILADEPTGNLDSKTTEEVMDLLKSSIKKYNQTLIIITHNENIARKADRIISIIDGE
                     LKLTL"
     gene            complement(4612..7188)
                     /locus_tag="JAM15_12875"
     CDS             complement(4612..7188)
                     /locus_tag="JAM15_12875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAT6799146.1"
                     /translation="MKDNLKIVLRYIKSYKTRSLAIVVSIILATSLVVGIGTLSRSAQ
                     QADVDRLKRELGTDHVYFKNIKKNQLKSIKSSKDIKNLGITSYYASTDVNEKLPINIL
                     YANKNYLTSHSKLIKGRFPKASNEVVVEKWILNSMGLKPEINQNLTFKLYQKENPETF
                     KVVGILEDRFIEKKKGQCEIFSNLNESKLNDFTTYIEFNEGSDINTNIDNIIKNAMLD
                     EKSIGRNSMLIESTMKNGTLDNSSKYVAIAMSLFAGIVIYSIYVISIYQRVQEYGVLR
                     AIGSTNFRIFKLMLYELFILALIAMPIGICIGMGGAQIFNRSVGNIQFEGNINVTPFV
                     IPDKIILLSIACTILIILIISFFTYLKIRRISPIDAIRKTFGADKNVTKVNYLISKLT
                     LNMSVTKSISAKNIFRNKKGFMIIVLSMSIGGIIVIKDNYKYSFLDVQNKSVQEQTYM
                     NADFILSNVYLNETGNNTSFKDIKGFSDSQIDKIKNIDGIDKVKTASILNTRIEVNKI
                     NRLDYYEAINSTPYYKLNPLFIKNKTTGKYTLKQKLKGYNDEMIKSLEKYLVSGNINL
                     KKMKKENLAIVYVPEISKTQKYTKTFTPGEGTPAVDIKVGDTIKVKYPKGGMDTGLYE
                     SLKDNYEYLEYEFKVGAIISYPFADNGMYSGDDSVDVITSSECLKKLTGVDKYNLVYA
                     DLNENANKKKINNLLGKIGSEVPGTTTVDMMVEKENSDKMTSRTMIYSYGIVAIMFII
                     SVLNIINNISYNLTSRTSEFGMLRAIGISEREFKNMILYEGILYGVLSSIITIVSGLI
                     IQFKMYYMQGFVSYGLGFSIDYKIYILVVVANIIVGILATYIPSRKINKISIVEAINI
                     TE"
     gene            7396..8331
                     /locus_tag="JAM15_12880"
     CDS             7396..8331
                     /locus_tag="JAM15_12880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAT6799147.1"
                     /translation="MDNNFVFPIVILTLFIFSNLIMNKYKFYKELDILKRGILTFFIS
                     CFALILLTEGTKYIQLRLGYSFLLEGVLNIILFLVLIILSFYTGFKVIRLINNNNEQE
                     YKLQKLDSKINHKDNIIIKLRSQKHDYLKHLQVVYSLLNTGLDEDAKGYIMNISNSFK
                     SKNSRYGKVSYLDAIASLKYEECLEKDISFDVYIQDFIDNLEIEPNDMSSVLLNIIDN
                     AIESLSTIKKEKKYIRLHAYEDEFQYIIAIKNNGPKIHNVESIFWNGFSTKEGQDRGY
                     GLHLVKNILDKYDYSILVNSDDFLTEFVILIPKYY"
     gene            8350..9087
                     /locus_tag="JAM15_12885"
     CDS             8350..9087
                     /locus_tag="JAM15_12885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6799148.1"
                     /translation="MIKVLICDDDKIVRDDIANIAKESGYVDYVKKVKDGIEAIEFIK
                     NEKIDLLIIDIDMPYKNGIDSAEEILSIDKDIHIVFVTGFADYSLESFKVHPIDFVVK
                     PFKKEKILDSINIAIDHINSHKIANNNFIEDTLFVYKIRKQIHMINFDDIVMFEKNSR
                     AINLHTKDEDIIKFYENFDDLKKRLPPNFFMTHRQYIVNLRFIHKVIPINKSSLEIRF
                     INFQENAILNKSLEKDFLYRFYRVKRF"
     gene            complement(9272..14329)
                     /locus_tag="JAM15_12890"
     CDS             complement(9272..14329)
                     /locus_tag="JAM15_12890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4132 domain-containing protein"
                     /protein_id="HAT6799149.1"
                     /translation="MLERTRVEKNPKIIENFKNNFTKSSSKQYYDLAKSLWDCIENSS
                     YYYREPEDKFLNMIKKYYNCHYYEIKNMDELLSGPLKNALELIFTSEQVEELCQLIKR
                     KMDYTYSGGYYRKGYRSNKLVDYFRGIIRFISNYVDLIYYDFSVIDYLTLPNKVLYYD
                     SIMSDKIALEIDKGNQKVTSALEEVIFGENQTALLTRQMIIGIMKSHSDKCYEMLSKL
                     LLAAKQQEGLRQQIVESLDEGTISASIYMLKTILDNNLERFSSVIRALDTWTGLGFSD
                     QKPGIIRKCLELSYKSLTDEKFRIESINSNDNLEIYFALWATATYNIYDSYSLIENLL
                     SCQEKYKKLVALYFLSHTESTYFKHSIASKNIKGDDLEILAWVITNFYVEGSVGYYYS
                     WQNRETNFDLSNTPIDKDFDARKEQFESLKHTLEILNSKTKSFSGSVFPWTWIEISSH
                     EILKCMMTLTAYDMNAQFIDVLMENCHLMSSDLRASLIVNFVNEPKTDRQREFLLECL
                     SDKSVSNRETVLSLLRKLELTDVELDKITNLLSLKTSSIRQTVIKILLEQDDSNLENI
                     ASSLIKSSNSQKCLGGLEIVNLLKDNSDRQELYNKLILLIEDIDKSKKNTSQVQILID
                     NLLGKAKNDYCKENGFGIYNPENKVQIPEQFDFKDDSNSSSKLNKIISNISLSTREDS
                     VSVATKKEAKKILDTDINKIIKVYEKFDELITENADYEYEVERWSGNVDKVLLGYSTY
                     NLTPIKYKVSNDTLDNYPLAELWRETSKKLDLDYKLILDILFYSISTCGYNETEKSWF
                     SSIYSNVLDSKKQNKIYTKLEKFKFNGLTRKLLRVLLNEFDHKEIFNYCLEIYYKLRN
                     LLTIEQCKKQRVEFTKNYYRQNEYCPALNAPILNYWLDKAHSFIYDDISFTKFFYTTF
                     SNYQLLEYKFPFYTSINVFARAHELGLMTEEQVNREMISGYNASNIIRTLTNPRWAGD
                     TLEKYPWLKDNLKTVTNRIIEIESRRGDMPTEVSHLANNIQYFEGIDYFVNILVALGK
                     ETFQRGYSYGSNYSKKDVLSSLLKNCYPTKEDDSKKLKSLLKNTDITELRLIESAMYA
                     PQWVNIIEKYLNWKGLKSTIWYFHAHINEGFSAQKESEVALFSPISPRSFIDGAFDVD
                     WFLDSYKTIGEERFNILYKSAKYITSGGNSHRRAQLYADATLGKLDKDMLMKEIETNR
                     NQDKLRSFSLLPMKKGDLKEATFRYEFIQKFAKESKQFGAQRRESESKACTIALENLA
                     RSAGFGDVNRMMWALETEKLNEVAHLFKPKDIDGTSIWIDVDENGKASTKVQKGNKSL
                     KSIPKAIAKHPYVLELKSVQKDLKSQYSRAKQSLEQAMKNEIVFTVKEIANIYKNPVI
                     CPLIKNLVWVCDDNIGYVYNDKSKFFICNIEGETYKLTAKNKLKLAHPVHLFESGKWS
                     EFQHDLFSKQIVQPFKQVFREYYRINSDELSEKTISRRYAGHQIQPKKTVALLRNQLW
                     TVDYEEGLQKVFYKENIVAKMFALADWFSPADIEPPTIETVEFFDRKTYKSLELASIP
                     PILFSEVMRDIDLVVSVAHAGGVDPETSHSTVEMRIAIAKELLLLLKINNINFEGSHV
                     LITGNLGEYSVHMGSGIVHKKGMGALNILPIHSQSRGKIFLPFADEDPKTAEIMSKIL
                     LLAEDNKIKDPSILSNL"
     gene            complement(14354..14773)
                     /locus_tag="JAM15_12895"
     CDS             complement(14354..14773)
                     /locus_tag="JAM15_12895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799150.1"
                     /translation="MQIYFRVKAVGKRKPMLELTPFDVSDNINCLKEAISEIVSKNVL
                     EYNEKIPEKSIINFLTNEEIESQADIGKVGFGSIYNENKQSVEKAIEVALQAFEDGIY
                     KVLINEDVIEKLDSPINLKSGDIFTFIRLTLLAGRMF"
     gene            complement(15006..15257)
                     /locus_tag="JAM15_12900"
     CDS             complement(15006..15257)
                     /locus_tag="JAM15_12900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002842548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799151.1"
                     /translation="MNRYTKIINMMGSYYTKDFEKEKKNVIKVREVKEDTVRKFFLQG
                     DCEVLVVFEDTGKEILIDDFSPEEDIKKYLGAKFINKKR"
     gene            15346..16077
                     /locus_tag="JAM15_12905"
     CDS             15346..16077
                     /locus_tag="JAM15_12905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HAT6799152.1"
                     /translation="MTSIKNKDILNCIDYSIKNKLFDKLNDVYKSLPVGNCSGCGNCC
                     MESVGINLIEFLNIFCYLEDRVDLKKSCISKILDYYFEEYTRKNPCPFKDTNNRCLIY
                     EVRPLNCRMFGHWKKEDYNKNLDNVIEKNNNYRELMKKQYGFEINDEVVNYRIDYCDR
                     FIPNKDYLSKSKRLSFFDELMILDSNIYSSGNIDIDFRDRGIVEYFIESLLYRNLAYN
                     VKIRISKEYKIRKRTIDRIKRIVLV"
     gene            16136..17047
                     /locus_tag="JAM15_12910"
     CDS             16136..17047
                     /locus_tag="JAM15_12910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAT6799153.1"
                     /translation="MNLTKVKGNTFFIKGGTNTGIYVFEDNTALMIDPGLCGSRPRRV
                     NKVLDENNIQVRYIINTHGHDDHYGACNQFKEYYKDVCIMSSEYDKLYIENPELFSKY
                     IVGGKSNVFMDNILKNKMLDDIKIDKSIEVGKIELNNEMFDIIEFQGHTPGSIAVLTK
                     DNVIFVGDLLIGDEILSKYDFLFLYDIQEQINSLEKLKNIDFEYLVLGHGKQVISKED
                     SYKLIEKHLNALKKYLYQIRELLVEPKSLEILLKNIINNNNLSNNYKEYHFFKSSLVS
                     VISYLVDLEEIGYILENGELLYYTKTK"
     gene            17098..17910
                     /locus_tag="JAM15_12915"
     CDS             17098..17910
                     /locus_tag="JAM15_12915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HAT6799154.1"
                     /translation="MEYEKWNEILAPYEHAVEELKIKFKNIRKEYLAKGEYSPIEFVT
                     GRTKKISSIISKLKRINAKDIETEIDDIAGIRIMCQFVEDIYAIVDLIKVRNDMTIIG
                     EKDYITNYKDSGYRSYHVIIKYPINSIAGSKEIICEIQIRTLAMNFWATIEHSLKYKY
                     DHYIPETLAERLRRASDAAFLLDQEMSEIREDIMKAQAMYQMKSIAIRDTLNRIQELY
                     DLGDTHKAMQYQRKLDRTETDKNITEILELKQEIDILLEQYKDTKVDDKVVQ"
     gene            18020..18712
                     /locus_tag="JAM15_12920"
     CDS             18020..18712
                     /locus_tag="JAM15_12920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HAT6799155.1"
                     /translation="MSLYAIGDLHFSTSVNKPMNIFGSNWDGHEKKIIDNWKEVVKEE
                     DMVLVLGDTSWGINLSEAKKDLDIISKLPGQKILIKGNHDYWWTTVTSLNKLYEDMRF
                     IQTNFYEYKDYAICGGRGWICPNDVKFDETDEKVYKREEHRLRLSLESARKSGHSKII
                     VITHYPPTNDKLEESLFTKLFEEYNVEKVIYGHLHGKESFKMGLKGIRNGVEYTLASC
                     DYTEFNLIKVHD"
     gene            18799..19740
                     /locus_tag="JAM15_12925"
     CDS             18799..19740
                     /locus_tag="JAM15_12925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799156.1"
                     /translation="MRWILVFIFLYLIPLVVIFRNYKNFKRSCIYSSIYVVLATTIMI
                     SNIYMSGLNKIKESMYYHNYISDETYDEKYVSNFKEKESTDLKQDKKKNEEISNNKNL
                     NNKQDRNIQNKESNEEGSNDIKEKNNSDSNVSVNNKSEKQEDNTKENNKYTSKEKNSE
                     DIKKIDMESIGIFKKEIYNIERAALVPMRECIPYTKDIAKNITKLSSIKKDVTNARNK
                     CKEVVKEYENMQIPELSKEKYTETLSNARDDVKKAYELREKSMESALKLINTKSPKYI
                     GKITEYLDLSDKQIESFKNRLNDLKEEINNSETNNIN"
     gene            19777..20934
                     /locus_tag="JAM15_12930"
     CDS             19777..20934
                     /locus_tag="JAM15_12930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HAT6799157.1"
                     /translation="MNKQSIGKLNMFFMGITQRNLDNRHFFIELEVIFKSGRKEFKGI
                     AIEEDNKYKFNFKGKSDLYTFNELLKNISKEAENYDGLVFKYVERGTIVVIEGDNKKV
                     NVKYLDNKEEVPKIDEFTASQIKNRDYYVKVGQANALLKEIGVLTKDGKIKNDKIRKY
                     NQIDHFVELIDSILKEIKDKDCITILDCACGKSYLSFVLNFYIKEVLKKNCYFIGIDY
                     SDVVIEASKNMAKNLGYKNMSFIKEDLTNYTPNRDVDLVISLHACDTATDMAIGLGIR
                     AKSEAIVVVPCCHKELLGQYRYEAMEPILKHGVFKARFADLITDGLRTLLLEGNGYDT
                     SVVEYISPLDTPKNLMIRAIKTKTNNDKALKEYKELKSQFGVEPTLEKLIY"
     gene            21086..21646
                     /locus_tag="JAM15_12935"
     CDS             21086..21646
                     /locus_tag="JAM15_12935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HAT6799158.1"
                     /translation="MNKLNICIDIDGTITSPYHFLPYLNDIFNKNITEAECITHNWEE
                     LYGSGIRDVYAEFNNKYIHSYDEAKIVEGATEVISTLSKGHNLSFVTARHECLTDVTK
                     NWLSRQGFSDIDVYLLGSDYKVEKARELSCDIFIEDNPLNSVQLADDGVKVILLDTNY
                     NKDVKHQNIVRVSNWIDIEKIIKQGI"
     gene            21674..22165
                     /locus_tag="JAM15_12940"
     CDS             21674..22165
                     /locus_tag="JAM15_12940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799159.1"
                     /translation="MIDLKIENRKGKIHVKSSEIKDILELRPDFEYVQDISNTINQEN
                     ILVFDCQLTGNSFDMDDLDIEEILEELGEEIDESYFSVLFEDVRAYLKDATDEIEADL
                     QDNYLFDNLRCYFDIYNINQEFTDFKFVFLVSFKDIKISSLANLAKIVSKRQLIGASK
                     FYS"
     gene            22394..22945
                     /locus_tag="JAM15_12945"
     CDS             22394..22945
                     /locus_tag="JAM15_12945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAT6799160.1"
                     /translation="MQSLNEIIAENLKKIRKEKHLSLDKIAQLSGVSKSMLSQIEKCE
                     VNPTISTLKKITNGLKISFTSLMERQESDIELIQKSDIDHFIEDNGKYISYPIFPFDS
                     KRRFEIFMIEIEEGGNLDSNAELPGTQEFITVFSGEVTIKINGEDYIVSSGNSIRFKA
                     DVSHIYRNSGKGIAKMSMVVYYI"
     gene            23031..23963
                     /locus_tag="JAM15_12950"
     CDS             23031..23963
                     /locus_tag="JAM15_12950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799161.1"
                     /translation="MNNKKAVFFFCSDLKKDPVASNVIKCCEEIMDLNQTDIVIDDNF
                     VLEFKDKNNNLFHFVKTKDVISHNYKYYLPILNRHFRDYDFAGVVNWHEGENAPEHIL
                     TAHTIGDVPTGEFGNSNPRYFKNLINAIEDIKNENLLDEFTTLTEATHWSGTAYGEES
                     KLITEYSVPMLDIEIGSSSDSFNNSIAIQVLAKSLIRVFDCDEPLKTLLCVGGVHFEK
                     SFSDIIKNKEYNISIGHVLPNQWIVSGMYDDESGFEKLEKCINSIEGGIDCIVFHDKL
                     KGTYKEQCRKLGEKLNVPVFKHKILKNPKDLPIW"
     gene            24018..24881
                     /locus_tag="JAM15_12955"
     CDS             24018..24881
                     /locus_tag="JAM15_12955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HAT6799162.1"
                     /translation="MILSYFALLIRVVLLAFERVVVRLLGDEEGDIYKNIASSFLFFF
                     IGGVCLLPFSIMDRVSDWSFLIPCYISSLVYSIGSVAYVTSLATGEVSLVTPINSLNS
                     LFLLLLSVIFLGEGLSLAKVAGIIIMIGGVFILKKVSSFLKNVSVIFNNLPCRLMFLY
                     IFLQSVGRVLDKAFFVQVSPILYSTILYFFVGLNLFIFLAFKKKQKIICEIFSNKKGL
                     SILSGAINGYSYLALLIALNNLELSIAEPFSQVSMIITLILAHFIFKENIKEKIPGSI
                     LILIGGWLLLL"
     gene            25128..>25437
                     /locus_tag="JAM15_12960"
     CDS             25128..>25437
                     /locus_tag="JAM15_12960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIB"
                     /protein_id="HAT6799163.1"
                     /translation="MNYKKTAIDIIEQVGGSKNILALEHCSTRLRFKLIDRSKVNQDA
                     LKKVQGVMSIVNGAQFQVVIGNSVVDVYDEILKVCPLDTNDSTVKTEEKINLGTRFIE
                     F"
BASE COUNT         9484 a         3069 c         3933 g         8951 t
ORIGIN      
        1 aaaaaattaa cggtcttaat ataaaaatta tttatctata tgaaaagcat aattattaca
       61 tattgactta aaaataactt atagagatta gaataatttt agtttgtata ttttttaaaa
      121 ccatacagtt gttataaaaa gaaaaattgc acacaagtca aaaataagtg ttattttata
      181 aaaatacgac aaaaatttta tttactactt atacaaataa catgcaaata acatataaaa
      241 tttaataagt aaaaaaaatg aaagatataa attatcattt tagtatttta tttagttgaa
      301 gtaaattatt caaatgaaat atatctcatt tagataaaaa attttagtaa aagtaaaaaa
      361 aataatatat ttgttaaaaa ataaattgac aaaatattca gaaaaaaact tcttgaccta
      421 agagagtaaa ataaataaaa tctaaggtat agagatgaaa tctataaaat tattttaagt
      481 ataagttaaa aatatagatg gtgcatttaa gatttataaa aattagagat gcataattat
      541 tttagggagg tttttagtat ggagaaaaaa gaaaaggtag tagaaaaatc aaatgttgaa
      601 gtatgtagtc ctgaaattgt caacagtgtt gaaacattaa gaatgagatt agaagaaatt
      661 agattggcac aaaaagaatt tgcaacattt acgcaagaac aggtagataa gattttctta
      721 gctgcttcaa ctgcagctaa tcaacaaaga atacctctag caaaaatggc agtggaagag
      781 actggtatgg gtattgttga agataaggtt ataaaaaacc attttgcctc agaatatatc
      841 tataatgctt ataaagatac taaaacttgt ggtgtcatag aaaaagatga agcatttggt
      901 tttacaagaa ttgctgagcc agtaggtgtt ttatcagcag ttataccaac aactaatcct
      961 acatcaactg caatattcaa atccctaata gcactaaaaa ctagaaatgg tataattttc
     1021 tctcctcatc caagagctaa aaactgtact atagaagcag ctagagttgt acatgatgcg
     1081 gcagttaagg caggagcacc aaaaggactt ataggttggg tagatgttcc ttcgattgaa
     1141 ttaactaatg ttgtcatggc agaggcagac cttatattag ctactggtgg acctggaatg
     1201 gttaaatctg catactcttc aggtaaacca gctgttggag ttgggcctgg aaatgtacct
     1261 gcaataatag atgagagtgc agatataaaa atggctgtaa gttcaatctt agtatcaaaa
     1321 tcattcgata atggtatgat atgtgcttcc gagcaagctg taatagtacc agaaaaaata
     1381 tatgaagaag ttaaaaaaga atttaaatac cgtggagcac atttcctaaa taaagaagaa
     1441 actgaaaaag taggaaaagt agtaataatt gatggttcat taaatgccag aatagttgga
     1501 caaccagcac atgtaatagc caaaatggcg gatgtagaag ttccaaaaac agctagaata
     1561 ataattggtg aagtagaatc tgttgaatta aatgaacctt ttgcacatga aaaactttct
     1621 cctgtacttg caatgtacaa gtctaaaagt tttgaagatg cagttgctaa agcagaaaaa
     1681 ttagttgcag atggaggcta tggtcataca tcttcattat atgcagactc tataaatcat
     1741 ccagagagag tagaaaagtt tgtaaatgct atgaagactt gtagagtatt agttaatact
     1801 ccatcatcac aaggtggtat aggtgattta tataacttta aattggcacc gtctcttact
     1861 cttggttgtg gttcttgggg tggaaactca gtatctgaaa acgttggagt aaaacatttg
     1921 cttaatatca agacagtagc tgaaaggaga gagaatatgc tttggttcag agcaccagaa
     1981 aaggtttatt tcaaaaaagg atgtttaggt gtagcagcaa gagaatttaa ggatgttatg
     2041 gataaaaaga aagcatttat agtaacagat tctttcctat ataataatgg atatactaag
     2101 aaattaactg atttattaga tgagatggga attaagcata ctacattctt tgatgtagct
     2161 ccagacccaa cattagcttg tgcaagagaa ggagctaaag ctatggctga tttccaacca
     2221 gatttaataa tagctgtagg tggaggaagt gcaatggatg ctggtaagat aatgtgggta
     2281 atgtatgagc atccagaagt agatttccaa gacttagcta tgagatttat ggatataaga
     2341 aaaagagtat atgtatttcc taagatgggt gaaaaagcgt attttgctgc tatcccaact
     2401 tcagcaggaa ctggttcaga agtaactcca tttgcagtta taactgacca agattcaggt
     2461 gtaaagtacc cattagcaga ttatgaatta atgccaaaca tggctataat tgatgctgat
     2521 atgatgatgg agatgccacc aagattaaca gcagcatcag gtgttgatgc tttaacacat
     2581 gcattagaag catatgtatc tatgttaaga actgaaccag ctgacggtct agcactacaa
     2641 gcaggtaaaa taatatttga atatttacct cgtgcatata aaaatggaaa gaatgataaa
     2701 gaagcaagag aaaaaatggc aatggcatct actatggcag gaatgtcttt tgcaaatgcc
     2761 ttcttaggaa tatgtcactc tttagcacat aaattaggtg cattccacca tgttcaacac
     2821 ggtgttgcaa atgcattatt aataaatgaa gtaatcaagt tcaattgtgc agaagctcca
     2881 aataagatgg gtgcattctc acaatacaga tatcctgatt gcatacaaag atatgctgaa
     2941 tttgcttctt ttgtaggtat taaaggaagt acagaccaag aaaaagtaga taatcttata
     3001 aaagcaatag atgaactaaa ggcaaaagta ggtcttccta agactataaa agaggctgga
     3061 gtagaagaat ctaaattctt agaaggattg gatgctatgg ttgaacaagc ttttgatgac
     3121 caatgtacag gtgctaatcc tagataccca ttgatgagtg aattaaaaga gatatatcta
     3181 aaagtttatt atggtaaata atattcattg tacaacatag gttctattgg gtttgtatat
     3241 aaattattag atttgaatat aaatagagtt ttattagaga cacgtagaag taactataaa
     3301 taatagatta taacttaaat tctgaatgga aatgataaaa agtcagtaat ttaatggtaa
     3361 tttcgaatat gtgtatttaa tcaattaact ttaaaattag tcggaaaatt tttttattac
     3421 atataatttt aaagcataat atataaaaaa ctttatgaaa aaattataaa aatattcaga
     3481 aaattctatt gactaattta tttatcatga tataataagt ttagaaaaga aaaaaattgg
     3541 ggcctattaa ggccccctta ctattttttg atagatttat ttaaaattac tttctcattt
     3601 tgatttttta tatttattat agagtcacta taatccactt caaagttggc aaaagcagag
     3661 aataaatcta tatctcttaa caaatgaatt gtcatacatt gattgttctt atttagcctt
     3721 agaatcaatg ctcttacaaa tggaaattgt attctagaat taaataagtt agaaccatca
     3781 gtatctatat ctaagctacg ataattaata tctataaata tatctacatc atcattttct
     3841 tctcttatta ttctgtagtc aaaatccaag tttaaattta aattacctaa aatcaataac
     3901 atttaaatcc tcttttctat aaatagtttt agagtgttaa tttaagctct ccatctatta
     3961 tagatataat tctatctgct tttctagcaa tattttcatt atgtgttatt attataagtg
     4021 tttggttata tttttttata gaacttttta gtaaatccat gacttcttct gtagttttac
     4081 tgtctaaatt tcctgttggt tcatctgcta ggattatact tggttttgca gataaagcac
     4141 gtgcaatagc aactctttgc tgttgaccac cagataattg gttgggaaga tgatttttcc
     4201 tttcattaag acccaataaa tttataaggt catcaatata ttctttatct atttttttat
     4261 tgtctaactt tagtggtaat tctatatttt cctttacatt taatacagga attaagttat
     4321 actgttgaaa gacaaatcct accttttgtc ttctatatct tgctaattct ttatctgaaa
     4381 gacaacatat atctttacca tctaccttta tagtaccatt acttggtctt tcaagaccac
     4441 ctactaaatg tagaaatgta ctttttccac ttccacttgg tccaattatt gcaacaaatt
     4501 cgcctttatt tatttttaaa tttgcattct ttagtgcatg tacagatgtt tcctttttcc
     4561 cataaatctt acctaaatta atagtttcca atataggcat aattatccct cctattctgt
     4621 aatgtttata gcttcaacta tactaatttt atttatcttt cttgatggaa tatatgtagc
     4681 tagaatacct acaattatat ttgctacaac aactagtata tatattttgt aatctattga
     4741 aaatcccaat ccatatgata caaagccctg catataatac attttaaatt gtattataag
     4801 tcctgacacg atagtaatta tacttgagag tacaccatat aatattcctt cataaagtat
     4861 catattttta aattctctct cagagatacc aatagctctt aacattccaa attcactagt
     4921 tcttgaagtt aagttataac ttatgttgtt tattatgtta agtacactga ttatgaacat
     4981 tattgctact atgccataac tataaatcat agttctagat gtcatcttat cagaattttc
     5041 tttttctacc atcatatcta ctgttgtagt tccaggaact tcacttccaa ttttacctaa
     5101 aaggttattt atttttttct tgtttgcatt ttcattaagg tctgcataaa ctaagttata
     5161 cttatctaca ccagttaatt tttttaggca ttcgctactc gttattacat ctacactatc
     5221 atctccagag tacataccat tatctgcaaa aggataactt ataatagctc caactttaaa
     5281 ttcatattct aagtattcat aattatcttt tagactttca taaagccctg tatccatccc
     5341 accctttgga tatttgactt ttatagtatc acctactttt atatctacag ctggtgtccc
     5401 ttcaccagga gtaaaagtct ttgtgtattt ctgtgtttta gaaatttctg gtacatatac
     5461 aatagctaaa ttttcttttt tcattttttt caagtttata tttccactta ctaagtattt
     5521 ttctaatgac tttatcatct catcattata accttttagc ttttgcttta gtgtatattt
     5581 gccagtagtc ttatttttta tgaacagagg atttagctta taataaggag ttgaatttat
     5641 agcttcgtag taatctaatc tatttatttt atttacctct attcttgtgt ttaagatact
     5701 agcagttttg actttgtcaa ttccatctat attttttatt ttatctatct gactatcact
     5761 aaaccctttt atatctttaa aagaagtatt gttaccagtt tcattgagat aaacatttga
     5821 tagaataaaa tctgcattca tatatgtttg ttcttgcacg gatttgtttt gcacatctaa
     5881 aaaagaatat ttataattat cttttatgac gattatacct cctatactca tagataatac
     5941 aattatcatg aacccctttt tatttctaaa gatgtttttc gcagatatag attttgttac
     6001 tgacatattt aaagttaatt ttgatattaa ataattaact ttggttacat ttttatcagc
     6061 tccaaaagtt tttctgatag catcaatagg agaaattctt cttattttta agtatgtaaa
     6121 gaaacttata attagtatta ttagtattgt acatgcaatt gataagagaa ttattttatc
     6181 tggaataaca aaaggtgtaa catttatatt tccttcaaat tgaatatttc ctacagacct
     6241 attaaatatt tgtgcacctc ccatacctat acatatacct atgggcattg ctattagagc
     6301 aagtatgaaa agttcataaa gcataagttt gaaaatccta aagttggtgg aaccaatagc
     6361 tcttaagacg ccatattcct gtactctttg gtatattgat ataacataga tactatatat
     6421 tacaatacca gcaaatagac tcatagcaat tgcaacgtat ttacttgaat tatctaaagt
     6481 accgtttttc atagtagatt ctataagcat tgagtttctt cctatacttt tctcatctaa
     6541 catagcattt tttattatat tgtctatgtt tgtatttata tcactgcctt cattaaattc
     6601 aatataagtt gtaaaatcat ttagttttga ttcattgaga ttagaaaaaa tttcacattg
     6661 tccctttttt ttctctataa atctatcttc aaggattcca acaactttaa aagtttctgg
     6721 attttctttt tgatataatt taaaagtaag gttttgattt atctctggtt ttaagcccat
     6781 actatttaaa atccatttct cgactaccac ctcattgcta gcttttggaa atcgaccttt
     6841 tataagttta gaatgactag tcaaataatt tttatttgca tatagtatgt ttataggtaa
     6901 tttttcatta acatctgtag acgcatagta agatgttata cccagatttt taatatcttt
     6961 gctagatttt atggacttta attgattttt ctttatattt ttaaagtata catggtcagt
     7021 tccaagttct cttttcaatc tatctacatc tgcttgctga gcacttcttg agagggtacc
     7081 aataccaaca acgagtgatg tagcaagaat tatactcaca acaattgcta aagacctagt
     7141 tttataactt tttatatacc ttagtactat tttcaaatta tctttcatat ttaccacttc
     7201 ctttcttaac taaatcaatt atatatttat ctaaaatata tagcaaagta agtattttca
     7261 aattttaagt agttaattgt acaaattcat ctgtgttttt acaagtttaa ttagtctata
     7321 tgtaaatttt aactttttac ataatttttt taaaatgata taatccctat ataaattgta
     7381 gaggggaggg gaatcatgga taacaatttt gtatttccta tagtaatact aactttgttt
     7441 atatttagca atcttataat gaataagtat aaattttaca aagaattaga catattaaaa
     7501 agaggcatat taacattttt tatatcgtgt tttgcattga ttttacttac ggagggcact
     7561 aaatatatac aattaaggtt aggatatagt tttttacttg aaggagtatt aaatattata
     7621 ctttttttgg ttttaattat tttaagtttt tatacaggct ttaaagttat aagattgata
     7681 aataataata atgaacagga atataaacta caaaaactag atagtaaaat aaatcacaag
     7741 gataatataa tcatcaaatt aagaagtcaa aaacatgact atttgaaaca tttgcaagta
     7801 gtgtattctc tattaaatac tgggctagat gaagatgcca aaggatatat aatgaatata
     7861 tcaaatagct ttaaatcaaa aaattcaagg tatggaaaag tatcttattt agatgctata
     7921 gcttcattaa aatacgagga atgtcttgaa aaggatatat cttttgatgt ctacattcaa
     7981 gattttattg ataatttaga gattgaacct aatgatatga gttcagtact attaaacata
     8041 atagataatg caatagagtc tttgtctact ataaaaaaag aaaagaagta tataagatta
     8101 catgcatatg aagatgaatt tcagtatatt atagctataa aaaataatgg tcctaaaata
     8161 cataatgttg aaagtatatt ttggaatgga tttagtacta aagagggaca agatagggga
     8221 tatgggctac atttagttaa aaatatatta gataagtatg attatagtat acttgtaaat
     8281 agtgatgatt ttttaactga atttgtaatc ttaatcccaa aatattatta gttaggagga
     8341 gaaaagtcta tgataaaagt tttgatttgt gatgatgata agattgtaag agatgatata
     8401 gcaaatatag ctaaagagtc tggatatgta gattatgtta aaaaagttaa agatggtata
     8461 gaggcaattg aatttataaa aaacgagaaa atagatttat tgattattga cattgatatg
     8521 ccatataaaa atgggattga ttctgctgaa gaaattcttt ctatagataa ggatatacat
     8581 atagtatttg tgacaggttt cgctgattat agtcttgaaa gctttaaagt gcatcctata
     8641 gattttgtag ttaaaccatt taaaaaagaa aaaatacttg attcaattaa catagcaata
     8701 gaccatatta actctcataa aattgctaat aataatttta tagaagacac cctttttgta
     8761 tataaaataa ggaagcagat acatatgatt aattttgatg atatagttat gtttgagaaa
     8821 aattcaagag caattaatct acacactaaa gatgaagata taataaagtt ttatgagaac
     8881 tttgatgatt taaaaaaacg cctacctcct aatttcttta tgacccatag acaatacata
     8941 gtaaatctaa gatttataca taaggttata cctataaata aatcttcatt agagataagg
     9001 tttataaatt ttcaagaaaa tgccatatta aacaaatctc tagaaaaaga ttttttatat
     9061 agattttata gggttaaaag attctagtga agatagaaga aaaatacttt ttatgtgata
     9121 taataagtac tgtaaagata atgtatagga gaagcttgta taaaaattat ttgtaattat
     9181 gatttaatct atataaatta cagtatagta tatattggac tttctaattt ttttaagaaa
     9241 gtccaatata ttttagagat agattttata cttataaatt acttaagata ctagggtctt
     9301 taatcttatt atcttcagca agtaatagta tcttagacat aatctcagca gttttagggt
     9361 cttcatcagc gaatggaagg aatatcttac ctctactttg agaatgtata ggaagtatat
     9421 tcaaagcacc catccctttt ttatgtacaa taccagaacc catatgcaca gaatactcac
     9481 ctaaattacc tgtgataaga acatgagagc cttcaaaatt gatattgtta atttttaata
     9541 ataataaaag ttctttagca attgctatac gcatctctac agtagaatgg ctagtttcag
     9601 ggtcaacacc accagcatga gcgacactta caacaaggtc tatatcacgc ataacttctg
     9661 agaatagaat tggaggtata gaagctaatt ctaaactttt ataagttttt ctatcaaaaa
     9721 attctactgt ttcaatagta ggaggctcta tatctgctgg tgaaaaccaa tctgcaagtg
     9781 caaacatctt tgccactata ttttctttat aaaatacttt ctgtaatccc tcttcataat
     9841 cgacagtcca aagctgattt ctaagaagtg ctacagtttt ctttggctga atttggtgac
     9901 cagcatatct gcgagatata gttttttcag ataattcatc actatttatt ctataatact
     9961 cacggaatac ttgcttaaat ggttgaacaa tttgcttact aaataaatca tgttggaact
    10021 cactccactt accagattca aacaaatgaa ctggatgtgc aagttttaat ttattttttg
    10081 ccgtcaactt ataagtttca ccttctatat tgcaaataaa gaacttagac ttatcattat
    10141 aaacatatcc aatattatca tcacataccc atactagatt tttaatcaaa gggcagataa
    10201 ctggattttt atagatattg gcaatttctt taactgtaaa tactatttca tttttcatag
    10261 cttgttctaa actctgtttt gcacgagaat actgactctt taaatctttt tggacagatt
    10321 taagttcaag tacatatgga tgtttagcaa tagcttttgg tatactcttt aaagacttgt
    10381 tgcctttttg aactttagta gatgcttttc cgttttcatc aacatctatc caaattgaag
    10441 taccatcaat atcttttggt ttaaatagat gagcaacttc atttagtttt tcagtctcaa
    10501 gagcccacat catacgattt acatctccaa atccagcact tctagctaga ttttctagcg
    10561 ctatagtaca agcttttgat tcactttcac gacgttgtgc accaaattgc ttgctttctt
    10621 tagcaaactt ttgaataaat tcataacgga aagttgcttc ttttaggtct ccttttttca
    10681 taggaagtaa agagaaactt ctcaatttat cttgatttct atttgtttca atttctttca
    10741 tcaacatgtc tttatcaagc ttaccaagtg tagcatcagc atagagttgt gcacgtctat
    10801 gagagttacc accactagtt atatatttag ctgacttgta aagtatattg aatctttctt
    10861 ccccaatagt tttatatgaa tctaagaacc aatctacatc aaatgcacca tcaatgaaac
    10921 tacgtggtga aataggggag aatagagcaa cctctgattc tttttgtgca gagaagcctt
    10981 catttatatg tgcatggaag taccaaattg tacttttcag acccttccag tttaaatatt
    11041 tttcaattat gtttacccat tgaggggcat acatagcaga ttctatcaat cttaactcag
    11101 taatgtcggt atttttaagt aaacttttta atttttttga atcatcttct ttagtaggat
    11161 agcaattttt aagtagagaa cttaaaacat ctttttttga ataattgcta ccatatgaat
    11221 atcctctctg gaaagtttct ttaccaagag cgaccaaaat atttacaaaa taatctatac
    11281 cttcaaagta ttgtatatta ttagctagat gagacacttc tgttggcata tcacctctac
    11341 gtgattcaat ttctataatt cggtttgtaa cagtttttaa attatcttta agccaagggt
    11401 acttttctaa tgtgtcacca gcccatctag gatttgttaa tgttcttatt atatttgatg
    11461 cgttgtatcc acttatcatt tctctattaa cttgctcttc agtcattaaa cctaattcat
    11521 gtgcacgagc aaacacattt atgctagtat agaaaggaaa cttatattct agcaactgat
    11581 aatttgaaaa cgtagtgtag aaaaacttag taaaagaaat atcatcataa ataaacgaat
    11641 gtgctttatc aagccaatag tttaaaatag gggcatttaa agcagggcag tattcatttt
    11701 gtctgtaata gtttttagta aattcaactc tttgtttttt acattgttct atagtcaata
    11761 agtttctaag tttatagtat atttctaaac aatagttaaa tatttcttta tggtcaaact
    11821 catttagtaa aactcttaaa agttttcttg taagtccatt aaatttaaat ttttcaagtt
    11881 ttgtatatat tttattttgt tttttagagt caaggacatt tgaatatata gatgaaaacc
    11941 aacttttttc tgtttcatta tatccacatg tacttatact ataaaataag atatcaagta
    12001 ttaatttgta atctaagtca agctttttac tagtttctct ccaaagttct gccaatggat
    12061 aattatcaag agtatcatta gaaactttat atttaatagg agtcaagtta taagtagaat
    12121 aacctaaaag cactttgtct acattacctg accatctttc aacttcatat tcataatctg
    12181 cattttcagt aataagctca tcaaattttt cataaacttt tattatttta tttatatccg
    12241 tatcgagaat tttttttgct tctttttttg ttgctacaga aacagaatcc tcacgagtag
    12301 ataaacttat atttgagata attttattaa gctttgatga gctattagaa tcatctttaa
    12361 aatcaaattg ttctggaatt tgaactttgt tttcagggtt atatattcca aaaccatttt
    12421 ctttgcagta atcatttttt gctttaccta acaaattatc aattagtatt tgaacttgag
    12481 atgtattctt tttagattta tcaatatcct ctataagtaa aataagctta ttatatagtt
    12541 cttgtctatc agaattgtct tttaataagt ttacaatttc aagacctcca aggcattttt
    12601 gagaatttga agattttatc agtgaagaag caatattttc caaatttgaa tcatcttgtt
    12661 caagtaaaat ttttattact gtttgtctaa tagagcttgt ctttaaagac aatagattgg
    12721 ttatcttatc taattctaca tctgttagct caagctttct aagtagactc aataccgttt
    12781 ctctattgga aacactctta tcacttaaac attccaataa aaattcacgt tgtctatctg
    12841 tctttggttc atttacaaaa ttgactataa gtgaagctct taaatctgaa ctcataagat
    12901 gacaattttc cataagcaca tctataaatt gagcattcat atcgtatgct gttaaagtca
    12961 tcatacattt aagtatttca tgagaagaaa tttcaatcca agtccatgga aatacacttc
    13021 ctgaaaatga ttttgtcttt gaatttaaaa tttctaaagt atgttttaaa ctttcaaatt
    13081 gttcttttct agcatcaaag tctttgtcaa taggagtgtt tgacaagtca aaattagttt
    13141 ctctgttttg ccaactatag tagtagccaa cagaaccttc tacatagaaa tttgtaatta
    13201 cccatgctag tatctctaaa tcatcaccct taatgttttt agatgctata gaatgtttaa
    13261 aatatgtact ttctgtatgc gataaaaagt aaagagctac aagtttttta tatttttcct
    13321 gacaagaaag taagttttca ataagagagt aagagtcata tatgttgtaa gttgcagtag
    13381 cccataaggc aaaataaatt tcaagattat cattgctatt aattgattct atacggaact
    13441 tttcatcagt caatgattta tatgaaagtt ctaaacattt acgtattatt ccaggttttt
    13501 ggtctgaaaa accaagtcct gtccatgtat ccaaggctct tataacagaa ctaaatcgct
    13561 ctaaattgtt gtccaaaata gtttttaaca tgtatattga tgcagaaatt gtaccctcat
    13621 ctaaactctc tacaatttgc tgtctaagtc cttcttgttg tttggctgcc aaaagaagtt
    13681 tagaaagcat ttcatagcat ttatcactat gactcttcat gataccaatt atcatttgtc
    13741 ttgtaagtag agcagtttga ttttctccaa atattacttc ttctaaggca cttgttactt
    13801 tttgatttcc tttgtctatt tctagtgcta ttttatcact cattatagag tcatagtaca
    13861 agaccttatt tggaagagta agataatcta taactgaaaa atcataataa attaaatcaa
    13921 catagtttga aataaacctt ataatacctc taaaataatc cacaagttta tttgagcgat
    13981 accctttacg ataatatcct cctgaatatg tataatccat ctttctttta attaattggc
    14041 aaagttcttc tacttgttca gaagtaaata ttaattctaa tgcatttttt aaaggtccag
    14101 aaaggagctc gtccatattt ttaatttcgt agtagtggca attgtagtat ttctttatca
    14161 tatttaagaa tttgtcttca ggttctctat aatagtatga actattttct atgcagtccc
    14221 aaagagattt tgctaagtcg tagtactgtt ttgaagaaga tttagtaaaa ttatttttaa
    14281 aattttcaat tattttagga tttttttcta ctctagtacg ttctaacatt tatgtacctc
    14341 caaattattt attttaaaac attcttccag caagcaaggt aagtcttata aaagtaaata
    14401 tatctccact tttcagattt ataggggaat cgagtttttc aataacatct tcatttataa
    14461 gcactttgta gattccatct tcaaatgcct gtaacgctac ttctattgcc ttttctacag
    14521 attgtttatt ctcattgtaa atagagccaa atccaacttt tccaatatca gcttgagatt
    14581 caatttcttc attagttaag aagtttatta ttgatttttc tgggattttc tcattatatt
    14641 caagaacatt tttagataca atttcagaga tagcttcttt taggcaattg atgttgtcag
    14701 atacatcaaa aggggtaagt tctaacatag gtttgcgttt gccaacagcc ttaactctaa
    14761 aataaatttg cataaaatca cctcgcaaaa tattaattat gtatttagaa atttaaaatt
    14821 tatctatttg ttatattata tcattttgtg aattattaat gtgaattatg gaattatttt
    14881 acaaaaaata gaaaaaaagc tatcttaaag tctaaaaaag caataaaaga taacttttaa
    14941 ctataattat atagaattat aactgtacat ttattaactt ttaattttag aattattttt
    15001 gataactatc tttttttatt tataaatttt gctcctaaat attttttgat atcttcttca
    15061 ggagaaaagt catcaataag tatttctttc ccagtgtctt caaatactac aagaacttca
    15121 cagtcacctt gtaagaaaaa ttttctaact gtatcttctt taacttctct aacttttatt
    15181 acattctttt tttctttttc aaagtctttt gtgtaataac ttcccatcat attaattatt
    15241 tttgtatatc tattcataaa atacctccat atgcgattaa atttaaaaaa tatgttataa
    15301 taattgtttg tattaactta ataattataa caaggagtaa taataatgac tagtataaaa
    15361 aataaagata ttttaaattg tatagattat tccattaaaa ataagctctt tgacaaacta
    15421 aatgatgtat ataagtcctt gccagtagga aattgttctg gatgtggaaa ttgttgtatg
    15481 gagtcagtag gtataaattt aattgagttt ttgaatatat tttgttatct tgaagataga
    15541 gttgatttaa aaaaaagctg tataagtaaa atattagatt attattttga ggagtataca
    15601 agaaagaacc catgtccatt taaagatact aataatagat gtctaatata tgaagttaga
    15661 ccattaaatt gtaggatgtt tggacattgg aaaaaagagg attataataa aaatttagat
    15721 aatgttattg agaaaaataa taactataga gagttaatga aaaagcaata tggatttgaa
    15781 ataaatgatg aagtagtaaa ttacaggata gattattgtg atagatttat tccaaataaa
    15841 gattatttaa gtaaatctaa gagattaagc ttttttgatg agcttatgat attagactca
    15901 aatatttatt caagtggaaa tatagatata gactttaggg atagaggtat agttgaatat
    15961 tttatagagt cattacttta tagaaattta gcatataatg tgaaaataag gatatctaaa
    16021 gaatacaaaa taagaaaaag aactatagat agaataaaaa gaattgttct tgtatagttt
    16081 tatattagta agtaataaat tgtatcataa atattgtcaa aatgaggtga ggaaggtgaa
    16141 tcttacaaaa gtaaaaggaa ataccttttt tataaaaggt ggcacgaata caggaatata
    16201 tgtatttgaa gataacacag cacttatgat agacccaggg ttatgtggtt caagacctag
    16261 gagagtaaat aaagtattag atgaaaataa tatacaggtt agatatatta taaatactca
    16321 tggtcatgat gaccactatg gagcttgtaa tcaatttaaa gaatattata aagatgtgtg
    16381 tataatgtca tctgaatacg acaaattata tatagaaaat ccagaattgt tttcaaagta
    16441 tattgttggg ggaaagagca atgtatttat ggataatatc ttaaaaaata aaatgttgga
    16501 tgatataaag atagataaat ctatagaagt tggaaaaatt gaattaaaca atgaaatgtt
    16561 tgatataatt gagtttcagg gtcatacacc tggtagtata gctgttttga cgaaggataa
    16621 tgtgattttt gttggcgatt tattgatagg agatgaaatt ttatcaaaat acgatttctt
    16681 gtttctatat gatatacaag aacaaataaa ttcattagaa aaattaaaaa atatagattt
    16741 tgagtactta gttttagggc atggcaagca agttatatcg aaagaagatt cttataaatt
    16801 aatagaaaaa catttgaatg ctttaaaaaa atatttatat caaataagag agttgcttgt
    16861 agaaccgaaa tctttagaaa ttttattaaa aaacattata aataacaata atttaagcaa
    16921 taattataaa gagtatcatt tttttaaatc ttcgttagta tctgtcataa gttacttagt
    16981 tgatttagaa gaaatagggt atatattgga aaatggagaa ttgctttact atacaaaaac
    17041 aaaataaatt atgataaaat aaagaaggtc ataaaaaaca aataaagggt gagcaatatg
    17101 gaatacgaaa aatggaatga gatactagca ccttatgaac atgcagtaga ggaattgaaa
    17161 ataaaattta aaaatataag aaaagaatat ttagcaaaag gtgaatattc tcccatagag
    17221 tttgtcacag gcagaacaaa aaaaatatct tccataatat ctaagttaaa aaggataaat
    17281 gcaaaagata tagaaactga aattgatgat attgctggta taagaataat gtgccagttt
    17341 gttgaggata tatatgctat agttgatttg ataaaagtaa gaaatgatat gactataata
    17401 ggagaaaaag attatattac aaattacaaa gatagtggtt atagaagcta tcatgttata
    17461 ataaaatacc ctataaactc cattgcgggt tcaaaggaaa ttatatgtga aatacaaata
    17521 agaactcttg caatgaattt ctgggctaca atagaacatt cattaaaata taaatatgac
    17581 cattacatac ctgagactct tgctgaaagg cttagaagag catctgatgc tgcctttctt
    17641 ttagaccaag aaatgagtga aataagagag gacataatga aagctcaggc tatgtaccaa
    17701 atgaagtcta tagctattag agatactcta aatagaatac aagagttata tgacttgggt
    17761 gatacacata aagctatgca gtaccaaaga aaacttgata gaactgaaac agataaaaat
    17821 ataactgaaa ttttggaatt aaaacaagaa atagatatat tactagagca atataaggat
    17881 actaaggtag atgataaagt agttcagtaa aaaactactt gtagaaaatt tgctaaatat
    17941 taatggggct gcctcttaat ggaaaataat ttctaaaaag agacagccta tttagtgtaa
    18001 ttaagaaagg aatgatatta tgagtttgta tgctataggt gatttacatt tttcaacatc
    18061 agtcaataag ccaatgaata tctttggaag taattgggat ggtcatgaaa agaaaattat
    18121 agataattgg aaagaagttg ttaaggaaga agatatggtc ttagtactag gagatacatc
    18181 ttggggaatt aatttatcgg aagctaaaaa agatttagat ataataagca aacttccagg
    18241 tcagaaaata cttataaaag gaaatcatga ttactggtgg acaaccgtta caagtttaaa
    18301 taagctatat gaagacatgc gttttattca gacaaatttt tatgaatata aagattatgc
    18361 aatttgtgga ggtaggggct ggatatgtcc taatgatgtt aaatttgatg agactgatga
    18421 aaaagtttat aaaagagaag aacatagact tagactatca ttagaatctg ctcgtaaaag
    18481 tggtcactca aaaataattg tgattactca ttatcctcct acgaatgata aattggaaga
    18541 atctttattt acaaagttat ttgaagaata taatgttgaa aaggtgattt atggtcactt
    18601 gcatggtaaa gaatctttta aaatgggatt gaaggggatt cgaaatggag tagaatatac
    18661 attagcatct tgtgactata cagaatttaa tttaataaaa gttcacgatt aaaaaacata
    18721 aattggtaaa tactataaga tacatgatta aaaataaata tttgagggat ttcggttttg
    18781 agaaaggaga cacgacttat gaggtggata ttagttttta tatttttata tcttattcct
    18841 ttagtagtga tattcagaaa ttacaagaat tttaagaggt cttgtatcta cagtagtatt
    18901 tatgtggtat tagctacaac aataatgata agtaatattt atatgagtgg acttaataaa
    18961 ataaaagagt ctatgtatta tcacaattat atctctgatg agacatatga tgaaaagtat
    19021 gtatcaaatt ttaaggaaaa agaaagtact gatttaaaac aggataagaa aaagaatgaa
    19081 gaaatatcaa ataataaaaa tttaaacaac aaacaagata gaaatataca aaataaagaa
    19141 agtaatgaag aaggaagtaa tgatataaaa gaaaagaata attctgatag taatgtttca
    19201 gtgaataata aatcagaaaa acaagaagat aatacaaaag aaaataataa atatacaagt
    19261 aaagaaaaaa atagtgaaga tataaaaaaa atagatatgg aaagtatagg aatttttaag
    19321 aaagaaattt ataatataga aagagcagct ttagttccaa tgagagaatg tataccttac
    19381 actaaggata tagcaaaaaa tataactaaa ttatctagta taaaaaaaga tgttacaaat
    19441 gccagaaaca agtgtaaaga agttgtaaaa gaatatgaaa atatgcagat tccagaactt
    19501 tctaaggaga agtatacaga aacattgagt aatgctagag atgacgtaaa gaaagcatat
    19561 gagcttagag aaaaatctat ggaaagtgct ttgaaattaa taaatactaa aagccctaaa
    19621 tatataggga agataacaga atatcttgat ttatcagata agcagataga aagttttaaa
    19681 aatagattga acgatttaaa agaagaaata aataattcag aaacaaataa tattaattaa
    19741 taagatttaa agatataagt taaaagggag attatgatga ataaacagag tataggaaaa
    19801 ctaaatatgt tttttatggg gattactcaa agaaaccttg ataataggca tttttttatt
    19861 gagttagagg tgatttttaa atctggaaga aaagagttta aaggaattgc aatagaggaa
    19921 gataataaat ataaatttaa ttttaaagga aaatcagatt tatatacgtt taatgagttg
    19981 cttaagaata tttctaaaga ggcagaaaat tatgatggat tagtatttaa atatgttgag
    20041 cgaggaacta ttgttgtaat tgaaggagac aataagaagg taaatgtaaa atatttagat
    20101 aataaggaag aagtacctaa aatagatgaa tttacggcat ctcaaataaa aaacagagat
    20161 tattatgtaa aagtaggaca agcaaatgca cttttaaaag aaattggagt acttacaaaa
    20221 gatggtaaga taaaaaatga taaaataaga aaatacaatc agatagacca ttttgttgaa
    20281 ttgatagata gtattttaaa agaaataaag gataaagact gtataactat cttggattgt
    20341 gcttgtggaa aatcttactt aagctttgtc ttaaattttt atataaaaga agtattgaag
    20401 aaaaactgtt attttatagg aatagattat tcagatgtag ttatagaagc atcaaaaaat
    20461 atggctaaaa acttgggtta taaaaatatg tcatttataa aagaggattt gactaattat
    20521 acacctaata gggatgttga ccttgtaata agtctacatg cttgtgatac agctacagat
    20581 atggcaatag gtctaggaat tagagcaaaa tctgaagcta tagtagtagt accatgttgt
    20641 cataaggagt tattagggca atatagatat gaagctatgg aaccaatatt aaaacatggt
    20701 gtatttaaag ctagatttgc agatttgata actgatggtt taagaacatt gttattggag
    20761 ggcaatggat atgatacttc tgtagtagaa tacatatctc cacttgatac accaaaaaat
    20821 ttaatgataa gagcgataaa aactaaaacg aataatgaca aagcattaaa agaatataaa
    20881 gaactgaaat cacaatttgg agtggaacca accttagaaa aacttatata ttagttaaaa
    20941 atgtaaaatt tacgaaaagc ttgcttaaat atgcaagctt tttggtatta tataggtata
    21001 gtcatatcca gagttttgat ttataattaa agctgtgcta taatatttga ttaatcaaat
    21061 caataaatgt tacatggagg taaaaatgaa caaattgaat atatgtattg atatagatgg
    21121 aacaataaca agcccttatc attttcttcc atacctaaat gatatcttta ataaaaatat
    21181 aactgaagca gagtgtataa cacataattg ggaagaattg tatggttcgg gaataagaga
    21241 tgtgtatgcg gagtttaata ataagtatat acactcatat gatgaagcaa agattgtaga
    21301 gggtgctaca gaggtaatta gcacattatc taaaggacat aatttatctt ttgtaacggc
    21361 tagacatgag tgtttaactg atgtaactaa aaattggcta tcgagacaag gattttcaga
    21421 tatagatgtt tacttattag gaagtgatta taaagttgaa aaggcaagag aactgagttg
    21481 tgacatattt atagaagata atcctttaaa ctcagtgcaa ctagctgatg atggtgttaa
    21541 agtaatactt ctggatacta actataataa agatgttaaa catcaaaata tagttagagt
    21601 tagtaattgg atagatattg aaaagattat aaaacaaggt atttaaagat ttgtagattg
    21661 aaagggggag catatgatag atttaaaaat tgaaaataga aaaggaaaaa tccatgtaaa
    21721 gagcagtgaa ataaaagaca ttttagaatt acgtccagac ttcgaatatg tacaagatat
    21781 atcaaatact ataaatcaag aaaatatatt ggtatttgat tgccagttga caggaaattc
    21841 ttttgatatg gatgatttag atatagaaga aatattggaa gagttaggtg aagaaataga
    21901 tgagtcttat ttcagtgttt tatttgaaga tgtaagagcg tatttaaaag atgctactga
    21961 tgagatagaa gcagacttac aggataatta cttatttgat aatttgagat gttattttga
    22021 tatatacaat ataaatcaag aatttacaga ttttaagttt gtatttttag tttcttttaa
    22081 agatataaaa atttcttcat tagcaaacct agctaagatt gtttctaaga gacagcttat
    22141 aggtgcatct aagttttata gttaaaatga aatattatta taataaaagc tagtagcctt
    22201 gtaaaaatat aggttactag ttttttattt gttcactttc acaaaatttc agaaaactat
    22261 ttacattcta aaaaaagtaa tgtatattaa acataatgta cagtataatg gataaaaagt
    22321 ttctattaaa ttactaagtt tatttaataa tcaaaataat ttatcttata ttagtatgta
    22381 ttagggggta tttatgcaaa gtttaaatga aataatcgct gaaaatttaa aaaagataag
    22441 gaaagaaaaa catcttagtt tagacaagat tgcacaactt agtggtgtaa gtaagagtat
    22501 gctatctcaa attgaaaagt gtgaggtaaa tcctactata tctactttga agaaaataac
    22561 taatggacta aaaatctcat ttacatcatt gatggagagg caggaaagtg acatagaatt
    22621 gattcaaaaa agtgatatag accattttat tgaagataat ggaaagtata taagttatcc
    22681 aatatttcca tttgactcca aaagaagatt tgagatattt atgattgaaa tagaagaagg
    22741 tggaaattta gattcaaatg ctgaacttcc aggaacacaa gagtttataa ctgtttttag
    22801 tggcgaagta accattaaaa taaatggaga agattacatt gtatctagtg gaaattctat
    22861 aagatttaaa gctgatgtat cacatatata tagaaactca ggcaaaggta tagctaaaat
    22921 gagtatggta gtatattata tataaataat ttaatggaat tagagtgata tttagatgat
    22981 tttaggtatg aagatatatt atatttaagt tataggagtg tgatttatgg atgaataata
    23041 aaaaagcagt ttttttcttt tgtagtgatt taaagaaaga cccagtagcc agtaatgtga
    23101 taaagtgttg tgaagaaata atggatttaa atcaaactga tattgttatt gatgataatt
    23161 ttgtattaga atttaaggat aaaaacaata acttatttca ttttgtaaaa acaaaagatg
    23221 taataagtca taattataaa tattatcttc caattttaaa tagacatttc agagattatg
    23281 attttgcagg agttgtaaat tggcatgagg gagaaaatgc tccagaacat atcctaacag
    23341 ctcatacaat tggagatgtt ccaacaggag aatttggaaa ttcaaatcca agatacttta
    23401 aaaatctaat caatgctatt gaggatataa aaaatgaaaa tctacttgat gaatttacta
    23461 cattaacaga agcaactcac tggtctggaa cagcatatgg tgaagaatct aaattaatta
    23521 cagaatattc tgtacctatg ttggatattg agataggaag tagtagtgat agttttaata
    23581 atagtatagc aatacaggta ttggcaaaat cattaattag agtatttgat tgtgatgaac
    23641 ctttgaagac tttattatgt gttggagggg tacattttga gaaatctttc tcagatatta
    23701 taaaaaataa agaatataac atatcaattg gacatgtatt gccaaatcaa tggattgtaa
    23761 gtggaatgta tgatgatgaa tcgggatttg agaaactaga aaagtgtata aatagtattg
    23821 aaggtggaat tgattgtata gtttttcatg ataaattaaa aggtacctat aaagagcaat
    23881 gccgtaaact aggtgaaaaa cttaatgtac ctgtatttaa acataaaata ttaaaaaatc
    23941 ccaaagactt acctatatgg tagtcttata cagttaatat aacaataagt cggattaatt
    24001 tttaagcgag gtcaaaaatg atattatctt attttgcatt attaattaga gtagtgctat
    24061 tagcttttga aagagtagtt gtaagattat taggtgatga agaaggagat atttataaaa
    24121 atatagcttc atcatttcta tttttcttta tagggggagt atgtttactt ccatttagca
    24181 taatggatag agttagtgat tggtcgtttt taataccatg ttatataagt agtttagtct
    24241 attcaattgg ttcagtagcg tatgtaacgt ctttagcaac tggagaagtt tcacttgtta
    24301 ctccaataaa tagtttaaat tcattgtttt tactgctttt atcagttata tttttaggtg
    24361 aaggtttaag tttagcaaaa gttgcaggaa tcataattat gattggtgga gtgtttatat
    24421 taaaaaaagt aagctctttt ttaaagaatg tctctgtaat ttttaacaat ttaccatgta
    24481 gattaatgtt tttatacata tttttgcagt cagtaggaag agtattggat aaggcttttt
    24541 ttgtacaagt atctcctata ttatattcaa ctatactgta ttttttcgta ggtttaaatt
    24601 tatttatctt tttagcattt aaaaagaaac aaaaaataat ttgtgagatt tttagtaata
    24661 aaaaggggct ttcaatttta agtggtgcta ttaatggata ttcttattta gcattattaa
    24721 ttgctttaaa taatctagaa cttagtatag cagagccatt ttctcaagta tctatgataa
    24781 taactttaat acttgctcat tttatattca aagaaaatat aaaagaaaaa ataccaggtt
    24841 caattttgat actaattggt gggtggctac tgttacttta attgatataa aaaatgaatt
    24901 ataaaggtgc tattagttag tatcagaaaa tttaaaaaag tattgacaat tcttttaggc
    24961 aaatgttaat ataataatac aaaatagtat aaatagaaga catgttactg gtaatgcagg
    25021 caggatcgaa tatattgctt tgatttttca aggtgtttat ataggttctg ccttttttgc
    25081 atcttgaatg gccattcata aaaaattatg gagaaggaga ttacaagatg aattataaaa
    25141 aaactgccat tgacattatt gaacaagttg gtggttcaaa aaatatttta gctttagaac
    25201 actgttcgac tagactacgc tttaagttga ttgatagaag taaagtcaat caggatgctt
    25261 taaaaaaagt acaaggtgtt atgagtatag ttaatggggc acaatttcaa gttgtcattg
    25321 gaaatagtgt tgttgatgtg tatgatgaaa ttttaaaagt ttgcccttta gatacaaatg
    25381 atagtactgt aaaaactgaa gaaaaaataa acttaggaac aagatttata gaattta
//
LOCUS       DACTZW010000062        24967 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.062, whole genome shotgun sequence.
ACCESSION   DACTZW010000062 DACTZW010000000
VERSION     DACTZW010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24967)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24967)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24967
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.062"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(98..1105)
                     /locus_tag="JAM15_12965"
     CDS             complement(98..1105)
                     /locus_tag="JAM15_12965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S55"
                     /protein_id="HAT6799164.1"
                     /translation="MQLKNFHFKNNTLSKKTNLAKSKFTIVLTFLFLLYFFSNNLIYA
                     QNLQKNEPEYLIPIGNVLQIDAELKNIIVRNPGEASPFRLGDAIVKVNNAEVDGYSDF
                     ANTLNALPEEKQVSILLNRGGQLITMKTTKHILEKISFNNLLSGFATLTYINPDTSEF
                     GAVGHPISVGNARKIPIKTGSISTTKHLNIEKSYKGSVGCINAKRENIIGSFTENTDF
                     GIRGQINNFDISNLKKYKVASLDEVKLGKAQIILQDNFNKCKKYNIEIIDIKNQKHPE
                     SKSFKIKITDKKLLAQTGGIVQGMSGTPIVQDNKIIGAVSHAIENDPAVGYGVFIKWM
                     L"
     gene            1333..2217
                     /locus_tag="JAM15_12970"
     CDS             1333..2217
                     /locus_tag="JAM15_12970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAT6799165.1"
                     /translation="MKKYRLLVTCIIAMGIIIIGTSNPVSNFYKTTNLISSGNITNEK
                     ADKDENSNKNNKDKNEDKSNSKSNKDKSSEDKSSDKKNKIQKNKKLLICIDPGHQGKG
                     DSNLEPVAPGSSSKKARVSSGTEGIATKKPEYVLNLEASLVLKSILESKGYNVIMTRE
                     THDVNISNSERAILANDKKADMVVRIHADSLNNSSKTGASILIPEKDGKYTAPIYEES
                     NKCAEFIKQNMEQSGIQINGIVQRGDLTGFNWSKVPAVLVEMGFMSNYNEDQMMSNPD
                     YQRKMMQCIADGLDAYFK"
     gene            2419..3969
                     /locus_tag="JAM15_12975"
     CDS             2419..3969
                     /locus_tag="JAM15_12975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAT6799166.1"
                     /translation="MLVVENVSHGFGARTILENVSFRLRKGEHIALVGANGEGKSSFL
                     NIITKKLMPDAGNIKWSSRATVGYLDQHTVLSKGKTIREVLREAFKHMFDLEQEMIAM
                     YDKMGEASDDEMSKLLEETAEIQTILENSGFYMIDAKIQEVANGLGLGEIGLDKDVTD
                     LSGGQRTKVLLTKLLLENPTILILDEPTNYLDEEHITWLTKYLQEYENSFVLVSHDIE
                     FINNTCNVIYHMENGELNRYKGNYDEFVRLNDIKKRQEEQAYDKQVEERKRLEDFVAR
                     NKARVATRGMANSRQKQLDKMEILERPKEKIKPTFAFKDARAASKIIFETENLVLGYD
                     EALTKPLNFHLERGKKIALKGMNGIGKSTLLKTLLGIIKPFEGNVKLGDYLEVGYFEQ
                     ESSRENSNTPMDEVWSEFPGLTNFEVRQALAKCGLTNEHITSQMRVLSGGEAAKVRLC
                     KVMLKNINFLVLDEPTNHLDVEAKDELKEAIKEFKGTVLLVCHEPEFYSEIVDDVWNI
                     EDFTTKIV"
     gene            3998..4645
                     /locus_tag="JAM15_12980"
     CDS             3998..4645
                     /locus_tag="JAM15_12980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HAT6799167.1"
                     /translation="MKKFLNVLFSVCISIVIIVGVINFTVGFKQLYYFDIDYLNISEL
                     SGLSEDDIKLNYDYLIDYNLNKNVSEFKLPTLKSSPQGKIHFEEVRNIFQNINKLAKL
                     LLVVFLVGIILSVKNKNIKILKTTSITLIIMPLLLTVPILLNFEKSFIIFHKLLFRND
                     YWIFNPDLDPVINMLPEEFFFHSGMMILILILLVSILLFVMYKLCKSLSIKIFQC"
     gene            complement(4787..5047)
                     /locus_tag="JAM15_12985"
     CDS             complement(4787..5047)
                     /locus_tag="JAM15_12985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-binding protein"
                     /protein_id="HAT6799168.1"
                     /translation="MGENYKFFNHKDCEFFPCHKTNKPEEFNCLFCYCPLYALGENCG
                     GNFKYTDKGIKDCSSCILPHKKDNYNYIMSKFQDLVKITSKK"
     gene            5264..6547
                     /gene="hflX"
                     /locus_tag="JAM15_12990"
     CDS             5264..6547
                     /gene="hflX"
                     /locus_tag="JAM15_12990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HAT6799169.1"
                     /translation="MKEIQEKALLVGLNLTTIVKKNDDIDTNESMEELTELTKAAGAE
                     VVGSLIQNKHSVDAAYYIGKGKVEEIRAYSDSLDATLVIFNDELSGAQIRNIENVVGR
                     KVIDRTTLILDIFAQRALSKEGKLQVELAQLKYRLPRLYGMGGEMSRTGAGIGTRGPG
                     EQKLEIDKRHILNKAADIRRELKEVKKNRETQRVKRLKSNIPIVALVGYTNAGKSTLL
                     NELIKTHKDYEQEKEVFVKDMLFATLDVTLRKALLPNKKEFLVVDTVGFVSKLPHDLV
                     EAFKATLEEVQYADLILHVIDATNTSYELQKSTTEGVLKELGVNDKKHILVYNKVDKL
                     ELDIYPKSQEDIVYISAKQGINMDKLLNMIEIALMENTYSVSLMLPYERGDIFSRIKD
                     KYNVENFEYGESGITLDVDLDEEDFNIYREYILEK"
     gene            6555..7232
                     /locus_tag="JAM15_12995"
     CDS             6555..7232
                     /locus_tag="JAM15_12995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HAT6799170.1"
                     /translation="MDINWENIDNLEDYFITYLLYKESKTVSQISKIRNISSTEASEQ
                     LIQAKLKIKEMQKDDFEASKDILDKFLELDKIKRLDFMDSLDDEKMVYFKRKVFKRIL
                     VEKNAEDLIVLIWATGELKDDRFLKLLHQLTNHRHSDIRRITYSAIRKIESPSSREVL
                     QKGLYDKNAQTRQYCAKALSKLGDENSLKILQQLKDKNKNFEKEYVLRAYDEAIKSLE
                     NAKNLKK"
     gene            7318..7761
                     /locus_tag="JAM15_13000"
     CDS             7318..7761
                     /locus_tag="JAM15_13000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HAT6799171.1"
                     /translation="MIVRRCAGGVVFYANKVLIVKNDRGEWTLPKGKILGGGLPYESA
                     VQRVKVETGIDAKMIDVAGDTMYEFFSRSRQQEVCNAIMWYVMEACNTDCVLAPEFQE
                     GGFYKVKDALAMLSHHKEQALVEVSYKKFKELKKLVSEGDDVPAN"
     gene            8066..8710
                     /locus_tag="JAM15_13005"
     CDS             8066..8710
                     /locus_tag="JAM15_13005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HAT6799172.1"
                     /translation="MSNYRTLHEFGTDEITIEKSVFIGYAKPIKSEEEALEFINEIKK
                     KHKDATHNVWAYTVGKNMNIQRYSDDGEPQGTAGIPTLEVIKKEDLRDVAVVVTRYFG
                     GTKLGAGGLVRAYTKGAKLGLEAGKIIYKVMYQEVKVKIDYTQLGKVQNELMNLGYFI
                     KDTVYEDNVEIVVYSRLEDVEKLSEKMIDITNGTGKIILGEEFYLSEQNGEILI"
     gene            complement(8796..9173)
                     /locus_tag="JAM15_13010"
     CDS             complement(8796..9173)
                     /locus_tag="JAM15_13010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HAT6799173.1"
                     /translation="MLFALIGFFAGIIGGMGMGGGTILIPALVLLAGIDTKIAQSVNL
                     LSSIPMTLIALAIHIKNKNVIFKLVIPIAVFGVLGAVFGSLLANYLSSDILKKIFGIF
                     LLLVGLFEVKKGFCAKSDKKPLN"
     gene            complement(9173..9559)
                     /locus_tag="JAM15_13015"
     CDS             complement(9173..9559)
                     /locus_tag="JAM15_13015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HAT6799174.1"
                     /translation="MKKTDDLKKKYFDFNLKNTIIGVFTGFINGVFGSGGGTLLVPIL
                     NDIVKVEEHKSHATALSIIIFLTTASSVLYVSKGTYDVNLTIKVAVGSILGGIIGAKL
                     LNKVTGKFLRISFGIIMIIAALRMVF"
     gene            9738..10493
                     /gene="nadE"
                     /locus_tag="JAM15_13020"
     CDS             9738..10493
                     /gene="nadE"
                     /locus_tag="JAM15_13020"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) synthase"
                     /protein_id="HAT6799175.1"
                     /translation="MSNIKIQIDKTVEWLINKVNEANAKGLIVGVSGGIDSAVVANLI
                     KKAFPENSMGVIMSIKSNPQDREDALKVIEGCDIEYLDLDLIEPQSAILDMVVGNLKD
                     KHLYRAEYLKMTDANLRARVRMSTIYTIANNLGYLVVGTDNAAEIHTGYFTKFGDGGV
                     DILPIANLTKGEVYEWAKELGVHEDLINKAPSAGLWEGQTDEDEMGTTYNMIDAVLEG
                     RLDEVPKRDQEIIERLHRLSEHKRKTPAQPPKF"
     gene            10576..11298
                     /locus_tag="JAM15_13025"
     CDS             10576..11298
                     /locus_tag="JAM15_13025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAT6799176.1"
                     /translation="MGRIGNIINRKGKQDAQRAKIFTKHARAIAVAAKEGGADPEYNA
                     ALKTAIEKAKADNMPNDNIDRAIAKGAGAGAGEDYETIVYEGYGPGGVAVIVETLTDN
                     KNRTAGNVRYYFDKNGGNLGTSGCVSFMFDKKGQILVGLGDGVSEEELMDVALEAGAE
                     DFITEEDGYEIITTPEDFSSVRDELKAKGYEFISADVKMIPQTTTVLTEESHLKMMNK
                     LVDMLEEDDDVQDIYHNWEVTE"
     gene            11943..12800
                     /locus_tag="JAM15_13030"
     CDS             11943..12800
                     /locus_tag="JAM15_13030"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAT6799177.1"
                     /translation="MYKYMNDVEIIINNMLDVFGINVKKSATFYKSRINNFFEIYMGT
                     DGNEYKPLDALTYYDVEIYLGKLRCSDAEKLNVYNALKRFFEYTYLEGKTKEIISQVK
                     RPTCIKKPNEVLNEEEYLKLKSFIVSRNENLNVRLILGLFLFTGLSRKYIANLRNNDF
                     KFDEGVYKLIIWKGDEEIQLPLKSELQLIINEYCNNLSDEEKFDKLVKISENAISDYI
                     SKLIDSIIGRRCTPTILSNTFISKALSSGNYIYEVSNLTLETVHTIAKHVKNDKDLIN
                     RQTSILNSF"
     gene            14004..14798
                     /locus_tag="JAM15_13035"
     CDS             14004..14798
                     /locus_tag="JAM15_13035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HAT6799178.1"
                     /translation="MESVMENLNNLKVEVKDKVCVITINRPKALNALNSDTLRELSQV
                     IDVVSENEAILGVIITGEGKVFVAGADIRQMQNYKSEEGRKYAGYAQGIFDKIEALEK
                     TVIAAVNGYALGGGCELAMSCDIRIASEKAIFGQPEVNLGVIPCFGGTQRLSRLVGTG
                     IAKELIFTGRQVNAEEAKSIGLINKVVPSDLLLEESMKMMNQIVEKAPIAIRYAKVVI
                     NKGIDMDLKNALELEKDIAGLTFATRDKQEGMNAFIEKRKPVFENK"
     gene            14892..16232
                     /locus_tag="JAM15_13040"
     CDS             14892..16232
                     /locus_tag="JAM15_13040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HAT6799179.1"
                     /translation="MNTGVIISLVGIIIALSLLVVMVMKGINIFIIAIVCSSLVAITG
                     SLNVYDALKVDYMTGFVGFLQANFFIFLTGTLMGKIMEITGGAKSIAKMIVRWIGKDK
                     ALLSIPIACGILAYGGVSVFVVSFAVFPIALEIFKEADLPRRFIPAALTFGCSTFAMV
                     APGAPQIQNIVPASTLGTDIMAGAVNGFISCAVMFIVGSTILYKMVSKEKANGGHFIA
                     HESDIFDEAEATNSKRENGPNGVIALIPLIVSILIINVKVNGKAIVPIEVGVFIGALL
                     VYLLLNKYQDNTKIVGHVGDACKTTVVAICNTCAVVAFGSVVKSAVGFDFIVNAMTNI
                     PGPPIAGAAVGTTVIAGICGSASGGLGIAAPLLGPVFLAKGVSAAALTRTMAISSAAL
                     DSLPHNGYIVTVTNGLCKETHKDAYMPIFWVTVLTPFIGTIVAVLLFTMFPGLP"
     gene            16369..17601
                     /locus_tag="JAM15_13045"
     CDS             16369..17601
                     /locus_tag="JAM15_13045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HAT6799180.1"
                     /translation="MLNKPLEGVKVIDLTYFVAGPGTSKILADWGADVIKVEPSFGDP
                     GRKTGATMTMPIDDYNNPFYSTYNSNKRGLSINLKSETGIEIMDKLLSEANVFVSSYR
                     TGALKRLGLDYESLSKKHPHLIWGQINGFGDFGPAKDNAGFDTVAFWARSGAMLDIAE
                     KDTSPINPPIAFGDATTSCSLSGGICAALYQQAKTGKGQKVMASLFGQAIWNASSLLA
                     STQFSDEYPKTRKNAISPVINSYRCKDGKWIFLSILEHERYFEALCRLFGREDLIKEE
                     KFASSVESKKNATELINILDGEFAKFTQNEMVEKLTAADIAHEKIQHVNDVVTDEQAI
                     ANNYIYEHTSKNGNKTMLASTPVKFGNIEVNMTCDAPLIGEHSDEILRELGYSDSDIE
                     ALIESGIVTMNKEACEIC"
     gene            17641..18783
                     /locus_tag="JAM15_13050"
     CDS             17641..18783
                     /locus_tag="JAM15_13050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HAT6799181.1"
                     /translation="MDFRLTEAQLMLQRVAKEFAENEIAPIAAETDKTGIFPRELFSK
                     MAKIGFNGIGTPVEYSGSGGTDIEKVIVVTEIAKKCAASAAILSIHTIYAQAILKFGT
                     EEQKKKYLPMMAEGGCVGAFALTEPNAGSDAARAATTAIIDEETDEYVLNGTKCFISG
                     GGQAESLIIFALTDPSKGIKGMSAIIVDKGTPGFSIGKIEEKMGIHGSETAELIFDNC
                     RVPKSNLLGKEGKGFNIAMTCLDGARIGVGAQAVGIAEGALEESIKYSKERVQFGKPI
                     SALQGIQWYIADMVTMVESAKLLVYYAADLKARGEKHTKEAAMAKYNASSTAREVTNL
                     ALQIHGGYGYMKDYPLERMYRDAKITEIYEGTSEIHKVVISRAVLG"
     gene            18794..19588
                     /locus_tag="JAM15_13055"
     CDS             18794..19588
                     /locus_tag="JAM15_13055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007593381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HAT6799182.1"
                     /translation="MNIVVCLKQVPDTNEVKINKETGTLIRDGVPSIINPDDRNALEE
                     ALKMKDELGAVIKVISMGPPQAKSALKEALAMGADEAYLISDRAFGGSDTWATSTIIA
                     AAIEKVGKYDVIFCGRQAIDGDTAQVGPEVAEFLGIPQVTYAKEVKVQDDKLLVTRYT
                     ETGDYLIEAKMPVLLTAIKELNNPRYPSVKGILEAYNNGDAKITVLTLADLDVDTTQI
                     GLKGSPTNVYKSFVPVKDKHNEIIEGINKKEKAEKLIEILFDLKLV"
     gene            19599..20621
                     /locus_tag="JAM15_13060"
     CDS             19599..20621
                     /locus_tag="JAM15_13060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HAT6799183.1"
                     /translation="MMRAKVNQGINLNDYNGVWVIGEQREGKINPVTIELIGEGRKLA
                     DQLGKELAVVIAGYEVEKEVKELLHYSIDKVYYINDPLLKDFTTDGYSISIANLIERK
                     KPEVVLVGATSIGRDIAPRIAGKVGTGLTADCTKLEIDSTDNKLLQTRPAFGGNLMAT
                     IVCPKNRPQMSTVRPGVMAKAVRNESETGILEVVTPELTEKMIRTRLVEILPQEKKSV
                     NLTDARIIVSGGRGLKRAEGFELIKELADKLGAEIGASRAAVDSGWIEHSHQVGQTGT
                     TVRPELYIACGISGAIQHLAGMSDSKYIVAINKDAKAPIFSICDYGIVGDLYEIIPEM
                     IESLNR"
     gene            20720..22096
                     /locus_tag="JAM15_13065"
     CDS             20720..22096
                     /locus_tag="JAM15_13065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HAT6799184.1"
                     /translation="MKEQWYKDIFARVLSMTDDGFIVVNTSGVIIDINDKYCDFLGKE
                     RKDIIGQNIQSIIPNTKMLDVMKDKYCEEGAIHHYSGGNTKEKSVIVSRSYVENDNGE
                     VVAGVAQVKFRLQSFDVAKKLMSEYMELQYYKEQFKDNCGFDKLIGENRDFIELKKTG
                     VKASKTNFPVLLTGETGTGKEVFARAIHNNSSRSDKPMVSINCAAIPEELLESELFGY
                     DEGAFTGAKKGGKKGKFLVANNGTIFLDEIGDMPLTMQAKLLRVLQESEIEPVGGLKT
                     IKIDVRVISATRKNLSKMVEEGLFREDLYYRLNVINIHMMELKDRQDDILLLANYILN
                     KLNVEYKELKVLSDKVKNCFINYTWPGNIRELQNVIKSAYAVSDDMVIMMCDLPSKMD
                     NISRVAQCNVDSNCSIHEMVENYEKSLIIDVLRKYNWKCSKAAEVMGIHKSLLYKKIK
                     KYEIELNN"
     gene            complement(22428..22772)
                     /locus_tag="JAM15_13070"
     CDS             complement(22428..22772)
                     /locus_tag="JAM15_13070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799185.1"
                     /translation="MDQIKRLHELQQKSYLTKEEFEELKNNTYIERFELRDECDNSYI
                     YTFYTNDKCNDIKFIKSQFIVTLIKIGFLCECGGVFRQKKIVDEYDYGYNAIYKCDSC
                     GKELDKEVENYD"
     gene            23260..24270
                     /locus_tag="JAM15_13075"
     CDS             23260..24270
                     /locus_tag="JAM15_13075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HAT6799186.1"
                     /translation="MHEDKNDIFESIDTEDFDNKTEEECLELVRKNGLNLIYIKNQTE
                     EICLEAVRQNCNAIKCVQNQTEKICIEAVKQDWRMLEFVEESTEEICMLAINQDGTAL
                     KYIENQTEELCLRAVEKNGAALEYVKEQTEEICIEAVRNSEFGLARVKNQTEKICMEA
                     VKHCSYNLKWVENQTEEICMEAVRQNGLDLKFVKNQTETICLRAVRQNGMALEFVKEQ
                     TVGICLKAVRQYGMALKFVKEQTEEICTEAIKQDKRALSFVKGDKEKYKALYDNNEPF
                     AKRYVRNVIEKENRALIKKGEENAKIKIAGKLYDRGMSFEDISDIVEIEISKLKVSLG
                     VF"
     gene            24406..24894
                     /locus_tag="JAM15_13080"
     CDS             24406..24894
                     /locus_tag="JAM15_13080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HAT6799187.1"
                     /translation="MKITVLYQTRSGNTERVAKLIEDGAKKVDGVDVKLMRLDNIDLD
                     YLNESKAVIFGTPTYLANTTWEVKKWFDEDSKKVNLAGKLGAVFATCDYICGGPDVAI
                     LTIVGHLMVKGMLVYSGGGSLGKPFIHLGHVHSIEGPELQDEKAIIFGERIATKAKEL
                     FA"
BASE COUNT         9764 a         2722 c         4599 g         7882 t
ORIGIN      
        1 ctaatatatt tggtctgtag gttaaataaa agtaccttta gaccaaatat attattaata
       61 acttaataac atcttaaaac ttatttattt atattattta caacatccat ttaataaata
      121 caccataacc tacagctggg tcgttttcaa ttgcatgtga cactgctccg attattttat
      181 tatcttgaac tattggagta ccactcatac cttgtacaat accaccagtt tgagctaaaa
      241 gctttttatc tgtaatttta attttaaaac ttttactttc tggatgtttt tggtttttta
      301 tatctataat ttcaatatta tattttttac acttattaaa gttatcttgt aaaattattt
      361 gagcttttcc taatttaact tcatctaaag atgctacttt atattttttt aaattggaaa
      421 tatcaaagtt attaatttga cctcttattc caaaatcagt attttctgta aagctaccaa
      481 taatattttc tcgttttgca tttatacatc caacactacc tttataagat ttttctatat
      541 taaggtgctt agttgtagaa attgaacctg ttttaatagg tatttttctt gcattaccaa
      601 cacttattgg atgacctaca gctccaaact ctgatgtatc tggattgata tacgttaaag
      661 tagcaaatcc agaaagtaaa ttgttaaaac taattttttc taatatgtgt ttggtagttt
      721 tcattgttat aagttgtcca cctctattta ataaaataga tacttgtttt tcttctggta
      781 aagcatttaa ggtattggca aagtcactat atccgtcaac ttcagcatta tttaccttta
      841 ctatagcatc acctaatcta aatggagatg cttctccagg atttctaact atgatatttt
      901 ttaattctgc gtcaatttga agtacgtttc caattggtat taaatattca ggttcatttt
      961 tttgtaaatt ttgtgcataa attaaattat ttgagaaaaa atataataaa aataaaaatg
     1021 ttaaaacaat tgtaaatttt gacttagcta agttggtttt tttacttaaa gtattatttt
     1081 taaaatgaaa atttttaagt tgcataaaac acctctttct tattaaatta ttttaataat
     1141 agaattgaag ttttcttgct gcttctatat tatgttgtgc aagaattatg ttttgatgct
     1201 tggaaaactg actcaataac accttagttt tcataaaaat aaataaaata aatagtgtat
     1261 atgataaaat aaatacatat tcatataaat aaaaataaac aataactgtc tagcataaga
     1321 aaggagcaaa aaatgaaaaa atatagattg ttagttactt gtataattgc catgggaatc
     1381 ataattatag gaacatcaaa tccagttagc aatttttaca agactacaaa tttgattagt
     1441 tcaggaaata tcacaaatga aaaagcagat aaagatgaaa attcaaacaa aaataataaa
     1501 gataaaaatg aagacaaatc taattctaaa agtaataaag ataagtcatc agaggacaaa
     1561 tcgtcagata aaaaaaataa aattcaaaaa aataaaaaac ttttaatttg tatagaccca
     1621 gggcatcaag gaaaaggaga tagcaattta gaaccagtag ctccaggttc ttcctctaaa
     1681 aaagcgagag tatcttcagg aacagagggt attgctacaa aaaaaccaga atatgttcta
     1741 aacttagaag catctcttgt tttaaagagt atattagaat ctaaaggtta taatgtaata
     1801 atgactagag agacacatga tgtaaatata agtaattcag agagagcaat acttgctaat
     1861 gataaaaaag cagatatggt tgtaagaata catgcagata gtttaaataa ttcttcaaaa
     1921 actggagcat ctatattgat tcctgaaaaa gatggaaaat atacagctcc tatatatgaa
     1981 gaaagtaata aatgtgctga atttatcaaa cagaatatgg aacaatcagg tatacaaatc
     2041 aatggaatcg ttcaaagagg tgatttgact ggatttaact ggtcaaaagt accagcagta
     2101 ttagtagaaa tgggatttat gagtaactat aatgaagacc aaatgatgtc aaatccagac
     2161 tatcaaagaa aaatgatgca gtgtatagct gatggattgg atgcgtattt taaataagat
     2221 atgaatagag aaaaagttag gttggtatta ttttcctaat ttttatctct attttttatt
     2281 gtacataacg caaagaagaa gtttatttta ggttaaattg tcgtaaatat aactaaaaat
     2341 attgggaata cttgatttaa gtttaaaaag aatatattat agtatagaat gtgtaaaatt
     2401 tttttgagag gtgttgaaat gctagtagta gaaaatgtga gtcatggatt tggtgcgaga
     2461 acaatattag aaaatgtatc ctttagactt agaaaaggtg aacatattgc actagttggt
     2521 gctaatggag aaggaaaatc gagtttttta aatataataa caaagaagct tatgccagat
     2581 gctggaaata taaaatggtc ttcaagagct acagtaggtt acttagacca acatacggta
     2641 ttaagcaagg gaaaaactat aagagaagtg cttagagagg cttttaagca tatgtttgac
     2701 ttagagcaag aaatgattgc tatgtatgac aaaatgggag aagctagtga tgatgaaatg
     2761 agtaagcttc ttgaagaaac agcagagata caaactatac ttgaaaatag tggtttttat
     2821 atgatagatg caaagataca agaagttgca aatggtcttg gtcttggaga aattggtctt
     2881 gataaagatg taactgactt aagtggaggg caaagaacaa aagtacttct tactaaactt
     2941 ctacttgaaa atccaactat tcttatattg gatgagccta caaactattt agacgaagag
     3001 catataacat ggcttactaa gtaccttcaa gagtatgaga atagttttgt cttagtttct
     3061 catgatattg aatttataaa taatacatgt aatgtaatat atcatatgga aaatggagag
     3121 ttaaatagat ataaaggaaa ttatgatgaa tttgtaagac ttaatgatat aaagaaacgt
     3181 caagaagaac aagcttatga taaacaagtt gaagaaagaa aaagactaga ggattttgta
     3241 gctagaaata aagctagagt agcaactaga ggaatggcta acagtagaca aaagcaactt
     3301 gataagatgg aaatattaga aagaccaaaa gaaaaaataa aacctacttt tgcttttaaa
     3361 gatgctagag cagctagtaa aataattttt gaaacagaga atttagtttt agggtatgat
     3421 gaagcattga caaaaccact taatttccat ttagaaagag gaaaaaagat tgccttaaaa
     3481 ggaatgaatg gtattgggaa atctactcta ttaaaaactt tacttggaat aataaaacca
     3541 tttgaaggaa atgttaaatt aggtgactat ttggaagttg gatattttga acaagagagt
     3601 tcaagggaaa atagtaatac acctatggat gaagtttgga gtgaatttcc agggcttaca
     3661 aactttgaag ttagacaggc tcttgcaaaa tgtggactta caaatgaaca tataactagt
     3721 caaatgagag tattaagtgg tggagaagct gctaaggtta gactttgcaa agtaatgtta
     3781 aaaaatataa atttcttagt attagatgag cctacaaatc atttagatgt tgaggcaaaa
     3841 gatgaattga aggaggctat caaagagttt aagggaacag ttcttttagt atgccatgag
     3901 ccagaatttt attcagaaat tgttgatgat gtatggaata tagaagattt taccactaaa
     3961 atcgtgtagt gatttaactt attgctgggg ggatttcatg aaaaagtttc taaatgtact
     4021 tttttcagtt tgtattagta ttgttataat agtaggtgtt attaatttta ctgttggatt
     4081 taaacaactt tattattttg acattgatta cttaaatata tcagagttat ctggtttatc
     4141 tgaagatgat ataaaattga actacgatta tctaattgat tataacttaa ataagaatgt
     4201 gtctgagttc aagttaccaa cattaaaatc ttctccacaa gggaagatac attttgaaga
     4261 agtcaggaat atatttcaaa atataaataa attagctaaa ttattattgg tagttttttt
     4321 agtaggaatt atattgagtg taaaaaataa aaatataaaa atcttgaaaa ctacgtcaat
     4381 aacacttata attatgccat tattattaac agttccaatt ttattaaatt ttgaaaagtc
     4441 atttattatt tttcataaat tattatttag aaatgattat tggatattta atcccgattt
     4501 agacccagtt ataaatatgt tgccagagga attctttttt cactctggaa tgatgatttt
     4561 aatattaatt ttgttagtaa gtatattact gtttgtaatg tataaattat gtaaatcttt
     4621 atcaataaaa atatttcaat gttaaataga gggatatttt tatttccaaa ataagataat
     4681 aaaaaaggat tagattaaaa gttatacaat aaaaatagct gtgcaataat atttagacta
     4741 tgaaagtagt taaaaaatat ttatgtacag ctatttataa tagaatttac tttttactag
     4801 tgattttaac taaatcttga aatttactca taatgtaatt gtaattatct tttttatgag
     4861 gtaatataca actactgcaa tctttgatac ctttatctgt atacttaaag tttccaccac
     4921 agttttctcc taaagcatac aaaggacaat agcaaaatag acagttaaac tcttctggtt
     4981 tattagtttt atgacaaggg aaaaattcgc aatctttgtg attaaaaaac ttataatttt
     5041 cgcccatatt ttcctcctaa ttaaataaaa tttaaatttt ttatactata taagattttg
     5101 gtgataatat aattatacta aataatttta tgaatagtcg ataatatagt attattaatc
     5161 atagtattaa tggtataatt agtcaacaga aaaataatgt aaaaataatg taagtgtatt
     5221 ttgcaattag aatatgtttt ataacaaaaa atgaggtgat taagtgaaag aaattcaaga
     5281 aaaagcactt cttgtaggtc tgaatttgac tacaatagtg aaaaaaaatg atgatataga
     5341 cactaatgaa tctatggaag aattaacaga actaacaaaa gctgctgggg cagaagttgt
     5401 aggtagctta attcaaaata aacactctgt agatgcagct tattatatag gaaaaggtaa
     5461 agtagaagaa ataagagcct atagtgactc tttagatgct actttagtaa tttttaatga
     5521 tgaattatct ggtgctcaaa tcagaaatat agagaatgtt gttggaagaa aagtaataga
     5581 tagaactact ttaattttag atatatttgc tcaaagggca cttagcaaag aaggtaaatt
     5641 acaagttgaa ttagcacaat taaaatatag attgccacga ctttatggaa tgggtggtga
     5701 gatgagtaga acaggtgcag ggattggtac tagaggtcct ggagaacaaa aactagaaat
     5761 agataagaga catatactta ataaagcagc agatataaga cgtgaactta aagaagtaaa
     5821 aaagaataga gagacacaga gagttaagcg tttaaagtca aatataccga ttgtagcact
     5881 tgttggatat acaaatgcag gaaaatctac cttgttgaac gaattaataa agacacacaa
     5941 ggattatgaa caagaaaaag aagtttttgt aaaagatatg ctttttgcaa ctttagatgt
     6001 aaccttgaga aaggctcttt tgccgaataa aaaagaattt ttagtagtag atactgttgg
     6061 atttgtaagt aaacttcccc atgatttagt agaagcgttt aaggcaacat tggaagaagt
     6121 acagtatgca gatttaatct tacatgtaat tgatgcaaca aatactagtt atgaattgca
     6181 aaaaagtacg actgaaggtg tattaaaaga acttggtgta aatgataaaa aacatatact
     6241 tgtatataat aaagtggaca agctagaatt ggatatatat cctaaaagtc aagaagatat
     6301 tgtgtatatt tctgcaaaac aaggcataaa tatggataag ttattaaata tgatagaaat
     6361 tgctttaatg gaaaatactt attcagtaag tttgatgtta ccttatgaga gaggtgatat
     6421 atttagtaga ataaaagata aatataatgt ggagaatttt gagtatgggg aaagtggtat
     6481 aacgctagat gtagatttag atgaagaaga ttttaatatc tatagagagt acatactaga
     6541 aaaataggtt gaatatggat ataaactggg aaaatataga taatcttgaa gattatttta
     6601 taacctatct tctttataaa gaatctaaaa cagtatctca aattagtaaa attagaaata
     6661 tttcaagtac tgaagcaagt gagcaactta tacaagcaaa gttaaaaata aaggaaatgc
     6721 aaaaagatga ttttgaggca tctaaggata ttttggataa atttctagaa ctagataaaa
     6781 ttaagagact tgattttatg gatagcttag atgacgaaaa aatggtatac tttaagagaa
     6841 aggttttcaa aagaatcctt gtagaaaaaa atgctgaaga tttaattgtt ttaatttggg
     6901 cgacaggtga gctaaaagat gataggtttt tgaaattgct tcatcagctc acaaaccaca
     6961 gacactcaga tattagaaga ataacttatt cagcaatcag aaagattgaa tcaccaagta
     7021 gtagagaagt actgcaaaaa ggtctctacg acaaaaatgc acagactagg cagtactgtg
     7081 caaaagctct ttcaaaattg ggagatgaaa acagtttaaa gattttacag cagttgaaag
     7141 acaagaataa gaattttgaa aaagaatatg tgcttagagc ttatgacgaa gccattaagt
     7201 cattggaaaa tgcaaaaaat ttgaaaaagt aattttttat taaagcaatt tgtttactta
     7261 atgatgtatt tctaaagttt aacaaggtaa taaataaatt aatgggaggg gtttcaaatg
     7321 atagtaagac gttgtgcagg tggagtagtg ttttatgcta ataaagtact tattgtaaaa
     7381 aatgataggg gtgaatggac acttccaaaa ggaaagatac taggaggggg acttccatat
     7441 gagagtgctg ttcaaagagt taaagtagaa actggcatag atgctaaaat gatagatgtg
     7501 gctggcgata ctatgtatga atttttctca agaagtagac aacaagaagt ttgtaatgca
     7561 ataatgtggt atgttatgga agcttgtaac actgattgtg tacttgctcc tgaatttcaa
     7621 gaaggtggat tttataaagt aaaggatgct ttagcaatgt tatcacatca taaagagcaa
     7681 gctttagtag aagtatctta taaaaagttt aaggaattaa agaaattagt ttcagagggc
     7741 gatgatgttc cagcaaatta attgtgaatt tagaggattc tgaggaaggg atagcccctt
     7801 ccttttttaa ttgaagcagt tttaagcgta aattatatag tctctttaaa ctatgattta
     7861 tcaatttaga gatttagtag tttatattta aaatcagtaa gatatattta aaataaaaat
     7921 taaaaagtat acaattttat tatataattg tcttatgatg ttgattaaag aattattaaa
     7981 agtccattta tttttaaata gaataatttt ataaatatat atttgatgtg tatattagaa
     8041 aatgattaaa ataggaggaa atacaatgag caattacagg acattacatg aatttggaac
     8101 agatgaaata actattgaaa agtctgtttt tattggatat gctaagccta taaagagtga
     8161 agaagaagca ttagagttta taaatgaaat aaagaaaaag cataaagatg caactcacaa
     8221 tgtgtgggct tatactgtag gtaaaaatat gaatatacaa agatatagtg atgatggaga
     8281 accacaagga acagctggga tacctacatt agaggttata aaaaaagaag atttgagaga
     8341 tgtagcggtt gttgttacta ggtattttgg aggaacaaaa ttaggtgcag ggggtctagt
     8401 tagagcttat acaaaaggtg ctaaactggg acttgaagca ggtaagataa tttataaggt
     8461 aatgtatcaa gaagttaagg ttaagataga ctatactcaa cttggaaaag tgcaaaatga
     8521 gttaatgaat ttggggtatt ttataaaaga tactgtatat gaggataatg ttgagatagt
     8581 agtgtattca agattagaag atgtagagaa attatcagaa aaaatgattg atataacaaa
     8641 tggaacagga aaaataattt taggagagga attttatttg tctgaacaaa atggagaaat
     8701 tttaatataa tctaaaaggt tattagaata gttaatacct caaatagcca attagtattt
     8761 ttaagtgaaa agccattaaa ttgatttaat ctaaatcaat ttaatggctt tttatcggat
     8821 tttgcacaga atcctttttt tacttcaaat aaacctacta aaagtaaaaa tatcccaaat
     8881 atttttttta atatatctga agacagataa ttagctaata gtgaaccaaa tacagctcct
     8941 aaaaccccaa acacagctat aggtataacc aatttaaaaa ttacattttt attttttata
     9001 tgtatagcaa gtgctataag tgtcataggg atagatgaaa gtaaatttac gctttgtgct
     9061 attttagtgt ctatgccagc aagtaaaacg agtgcaggta taaggattgt tcctccaccc
     9121 attcccattc ctccaataat tcctgcaaaa aatccaatta gagcaaataa cattaaaaca
     9181 ccatccttaa tgctgcaatt atcataatta ttccaaaaga aattctaaga aactttccag
     9241 taaccttatt tagtaattta gctcctataa taccaccaag aatacttcca actgcaactt
     9301 taattgttaa gttaacatca taagtacctt tagatacata taaaacagaa cttgctgtcg
     9361 ttaagaatat tattatagaa agagcagttg catgagattt atgttcttct accttaacga
     9421 tgtcatttaa tattggaact aaaagagtac ctcctccaga accaaaaact ccatttataa
     9481 atcctgtaaa aactccaatt atcgtatttt ttaagttaaa atcaaagtat tttttcttta
     9541 aatcatcagt ttttttcata aaaatcacct tctgaaatag ttttaccaaa ataggcaaat
     9601 tatatttata taaaataaga ttaaatataa tctttcatgt ttgtttaatt ttgcataaaa
     9661 aaaaacatat taaaacaaca tattaatata tggtataata tattaaaaca aagtagcaaa
     9721 tttgagagga gataacaatg tcaaatataa aaatacaaat agacaaaact gtagaatggc
     9781 ttataaataa ggttaatgag gcaaatgcaa aaggattaat tgttggtgta tctggaggaa
     9841 ttgattcggc agtagttgct aatttaatta aaaaggcatt tccagaaaac tctatgggag
     9901 ttataatgag cataaaaagt aatcctcaag atagagaaga tgcacttaag gttatagagg
     9961 gatgtgatat agaatacctt gatttagacc ttatagaacc acaaagtgct atattagaca
    10021 tggtagtagg aaatttaaaa gataaacatt tatatagagc agaatattta aagatgacag
    10081 atgcgaactt aagagcaaga gtaagaatga gtacaattta tacaattgct aacaatctag
    10141 gatatttagt tgttggtaca gacaatgctg cagaaataca cacaggatat tttactaaat
    10201 ttggtgatgg tggagttgat attttaccta ttgcaaattt aactaaagga gaagtatatg
    10261 aatgggcaaa agagcttggt gttcatgaag atttaataaa caaagctcct tcagcaggtc
    10321 tttgggaagg tcaaacagat gaagatgaaa tgggaactac ttacaatatg atagatgctg
    10381 tgttagaagg tagattggat gaagttccta aaagagacca agagataata gaaagacttc
    10441 atagattaag tgaacacaag agaaaaacgc ctgcacaacc tcctaagttc taatttacta
    10501 tttataagat ttgtgataaa atttacaagt gatgaaaatt agaataatta attgtacgta
    10561 ttaaggagtg gaaatatggg acgtataggt aatataatta atagaaaagg taaacaagat
    10621 gctcaaagag caaagatatt tactaaacat gctagagcaa tagcagttgc agctaaagaa
    10681 ggtggagcag acccagagta caatgcagcg ttaaaaacag ctatagaaaa agctaaggca
    10741 gataatatgc caaatgataa tatagataga gctatcgcta aaggtgctgg agcaggcgct
    10801 ggagaagact atgaaactat agtttatgaa ggatatggac ctggtggagt tgctgttata
    10861 gtagaaactt taactgacaa caaaaacaga actgctggta acgtaagata ctattttgac
    10921 aaaaacggag gaaacttagg aactagtgga tgtgtgtctt ttatgtttga taaaaaagga
    10981 caaatattag ttggtttagg agatggagtt tcagaagaag aattgatgga tgttgcatta
    11041 gaagcaggag ctgaagattt cataacagaa gaagatggtt atgaaataat aactacacca
    11101 gaagattttt ctagtgttcg tgatgagtta aaagctaaag gatatgagtt tatatctgct
    11161 gatgtgaaga tgatacctca aactacgact gtattgactg aagaatctca tttaaaaatg
    11221 atgaataaat tagttgatat gcttgaagaa gatgatgatg ttcaagatat atatcataac
    11281 tgggaagtaa ctgaataatg ctttaaagtc agtaatcata tatgatataa ttcataacga
    11341 ttatgatata aataattata gtttttgttg aagatgtatg aataaatatt atatacattt
    11401 aatcagtata tacctctttt tatagaaaat ataggacttt ctataaaaag aggtatattt
    11461 tttgtgtaat taaattaact aaatcggaag aaaaatattt aagtgccttt taaagtttgt
    11521 ttaaaagaaa actacatagg aataaatata ataaatttat agaagttatt tgtggaaagt
    11581 ggaaaaatac ctatgtacat aataacagta ttatatattt taagtaaaaa attttaggtg
    11641 attattttga aagggataaa atatatgttg aaaagaatta ttatatttga cttatattat
    11701 aaaaataaaa atagaatcta aacttagaaa taaggaataa aaatattaaa aaatgttact
    11761 aatataaaat tgtaatatag tattagtaaa cttttaaatt caaataaaag atagagataa
    11821 ttatacaata cattttttat atctagaata caatgaatta tacatgaaat aaaaaggttt
    11881 ttatcataaa atgtagaaat gtatattaaa tagattaaat gttctagtaa aggagtattg
    11941 atatgtataa atatatgaat gatgttgaaa ttataataaa taatatgcta gatgttttcg
    12001 gaattaatgt caagaaaagt gcaacctttt ataaaagtag aattaataat ttttttgaaa
    12061 tttatatggg aacagatggt aatgaatata agccattaga tgctttgaca tactacgatg
    12121 ttgaaatata tttaggaaaa ttgagatgta gtgatgcaga aaaattaaat gtatataacg
    12181 cactaaagag attttttgaa tatacttacc ttgaaggtaa aacgaaggag attataagcc
    12241 aagtaaaaag acctacttgt attaaaaaac caaatgaagt tctgaatgaa gaagaatatc
    12301 taaagttaaa aagctttata gtttctagaa atgaaaattt aaatgtacgt ttaattttag
    12361 gattatttct ttttacaggt ttgagtagaa aatatattgc aaacctaagg aacaatgact
    12421 ttaaatttga cgaaggtgta tataaattaa ttatttggaa aggggatgaa gaaatccaac
    12481 ttcctttaaa atcagaactc caattaatta taaacgaata ttgtaacaac ttatcagatg
    12541 aagaaaaatt tgataagctt gtaaagataa gtgaaaacgc tataagtgat tatatatcaa
    12601 aattaataga tagtataata gggagacgtt gcactccaac tatactatca aatactttta
    12661 tatctaaggc actttcaagt ggaaattata tatatgaagt gagtaattta acattggaaa
    12721 cagttcatac aatagcgaag cacgtaaaaa atgataaaga cttgattaat agacaaacat
    12781 caatattaaa tagtttttaa ataaaatgat ggtttgtttt aagtaataat cagattactt
    12841 ttataatcta ataaagataa gcgagtgtca ccaaactaaa aaatggagca attccatttt
    12901 tatacaacaa agataaatta gttaaaaaac tgttacataa caattataaa ttgttatgta
    12961 acagcttttt tacatttaaa taactttgaa agagcatgtt tataaaatta agaatcatta
    13021 tagcaggttt tgagcagggc ttgattgctt ataaataatt gatgggtata taacttgttg
    13081 ctaaatactg tttatacgag cggttactgt atcaataatc atcctaatac tacgttctgc
    13141 cgtttcttcc attttaaaat ctataactat caaatgagga atacttcttg atattagtca
    13201 tcctattata ggaaatatga aagtcaatgg aaatccagtt aagttgatga caacaaaagc
    13261 taaaattgat atgccagcac catctctagg ggaaagtaac taggagattt ataatggttg
    13321 gcttggtttt gatagtgata aaataaaaga tttaaaagaa aatggagtta tttgattaaa
    13381 aaatagctaa atacacttgt gactttagtc atgggaggtt cagttagaat aatatcaaaa
    13441 aatattaaat caatactgta aatcaaatat agaattgtca gaagcattta agatgggaaa
    13501 agctacttag acattgagtc tttgtggctt ttcctatttt cattaagaac tttatattat
    13561 cagaatagat atgtactaaa ctaaagtatt aacaatttaa attaatagaa aataaactac
    13621 ctaattatgt tgaataaaga ctactttagt gaaaataaac ttatagagat gctatttaaa
    13681 ttattttaat gggaatatca aaaatgagac tgcattctca aaaatgagac tgcgtttttt
    13741 aagtattttc tcgaaaatga gacaaaaata ttgttttatg ggttttattg aagaaaaatt
    13801 cttctgtgaa ttacaattta atcaatttta aagttgaaaa ttattaaaaa tttagtgaaa
    13861 tttatgtata tttcgtttat tttattaaaa ataacaattt tttactaaaa ataaagaact
    13921 tcaatggtga ttggcatagt acttgctatt ttatattaac aagaaatgta gaaaaaataa
    13981 caatgtataa tggggggaat atgatggaat ctgtaatgga aaatttgaac aatcttaagg
    14041 tggaggttaa ggacaaagtc tgtgttatta ctataaatag acctaaagct ttaaatgctc
    14101 ttaatagtga cactcttagg gaactatcac aagttattga tgtagtatca gaaaatgagg
    14161 caatattagg agttattatt actggagaag gtaaagtttt tgtagccggt gctgatatac
    14221 gccagatgca aaactataaa agtgaggaag gtagaaaata tgcaggttat gctcagggaa
    14281 tttttgataa aattgaagct cttgagaaaa cagtaatagc agcagttaat ggatatgcat
    14341 taggtggtgg atgtgaactt gctatgagtt gtgatattag aattgcatca gaaaaggcta
    14401 tatttggaca acctgaagtt aatttaggag ttattccatg ttttggtgga actcaaagat
    14461 tatcaagact tgttggaact ggaatagcta aagagttaat ttttacgggg agacaagtaa
    14521 atgcagaaga agctaaatct attgggctta ttaataaagt ggttccaagt gatttacttt
    14581 tagaagagtc tatgaagatg atgaaccaaa tagttgaaaa agcgccaata gcaataagat
    14641 atgcaaaagt tgttattaac aaagggatag atatggattt aaagaatgct cttgaactag
    14701 agaaagatat tgcaggttta acttttgcta caagagataa gcaagaagga atgaatgcat
    14761 ttatagaaaa gagaaagcca gtttttgaaa ataagtagct attataacta aattggaaca
    14821 atgtagaata tattcaaaat ctaaatttcg tgaaaaaata catatagttt aattttaaaa
    14881 ggagttaatt tatgaatacg ggagtaatta taagtttagt agggattatc atagctctat
    14941 ctcttctagt tgtaatggtt atgaagggaa taaatatttt tattatagca attgtatgtt
    15001 catcattagt tgctataaca ggaagcctaa atgtgtatga tgcacttaaa gtggattata
    15061 tgacaggatt tgttggattt cttcaggcaa atttctttat tttcctaaca gggacattaa
    15121 tgggaaaaat aatggagatt actggtggag caaaatctat tgctaagatg attgtaagat
    15181 ggattggtaa ggataaagca ctactttcta ttccaatagc ttgtggaata ttagcctatg
    15241 gtggagtaag tgttttcgtt gtaagttttg cagtgtttcc gatagcttta gaaattttta
    15301 aagaagctga tttgccacga agatttatac cagcagcttt gacttttgga tgctcaactt
    15361 ttgctatggt tgcaccaggg gcaccacaaa ttcagaatat tgttccagca tcaacattag
    15421 ggacagatat tatggctgga gcagtaaatg gttttatatc atgtgcagta atgtttatag
    15481 ttggaagtac cattttgtac aaaatggttt caaaagaaaa agccaatggt ggtcatttta
    15541 tagcacatga atcagatata tttgatgaag cagaagcaac taattctaag agagaaaatg
    15601 gtcctaatgg tgtaattgcc ttaattccat tgatagtgtc aattttaata attaatgtaa
    15661 aagttaatgg aaaagcgata gtaccaattg aggtgggagt atttattgga gctttattag
    15721 tatatttatt gttaaataaa tatcaagata atactaaaat agttggacat gttggtgatg
    15781 catgtaaaac tacagtagta gcaatatgta atacttgtgc tgtagttgca tttggttcag
    15841 tagtaaaatc agcagttggt tttgacttca tagttaatgc catgactaat attcctggtc
    15901 ctcctattgc aggggctgca gttggaacta cagttattgc aggtatttgt gggtcagctt
    15961 caggtggact aggaattgca gctccacttc ttggaccagt atttttagcc aagggtgttt
    16021 ccgctgcagc attaactagg actatggcaa tttcatcagc agcattagat tcacttccac
    16081 acaatggata tattgttact gtaacaaatg gtctgtgtaa agaaacacat aaggatgcct
    16141 atatgccaat attctgggta actgttttaa ctccgtttat tggaaccata gtagcagtcc
    16201 tactgtttac aatgttcccg ggattgccat aagagaaaag ataaaaggta taaattatat
    16261 tttgatatta taaaatcaat tttcaaaata tatacaataa atttcatgtt ttaatactgt
    16321 aaatatgtat ttaaaataac aaattgacca tataaggagg aattgaaagt gttaaataaa
    16381 ccattagagg gagttaaggt tattgaccta acgtattttg tagcaggtcc agggacttct
    16441 aaaatattag ctgattgggg tgctgacgtt attaaggtag agccaagctt tggagaccca
    16501 ggaagaaaga caggggcaac aatgacaatg ccaatagatg attataataa tcctttttac
    16561 agcacatata attcaaataa aagaggtttg tctataaatc ttaagagtga aactggaatt
    16621 gaaattatgg ataagctttt aagtgaagca aacgtatttg tttcaagtta tagaacagga
    16681 gcattaaaaa gactaggtct tgattatgaa tcattaagta aaaagcatcc acaccttatc
    16741 tggggtcaga taaatggttt tggcgatttt ggacctgcta aggataatgc aggatttgat
    16801 acagttgcct tttgggcaag aagtggggct atgcttgata tagcagaaaa agatacaagt
    16861 ccaataaatc cacctatagc ctttggagat gcaacaactt cttgtagttt atctggagga
    16921 atatgtgcag ctttgtacca gcaagctaag actggaaaag gacaaaaagt aatggcatct
    16981 ttatttgggc aagcaatatg gaatgcatca tctttattag catctacaca gtttagtgat
    17041 gagtatccaa aaactagaaa aaatgctatt tcaccagtaa taaattctta tcgttgtaag
    17101 gatggaaagt ggatattctt aagtatttta gagcatgaaa gatattttga ggcactttgt
    17161 agattatttg gaagagaaga cttaataaaa gaagagaaat ttgcatcttc agtagaaagt
    17221 aagaaaaatg ctacagaact tattaatatt ttggatggtg aatttgcaaa gtttactcaa
    17281 aatgagatgg ttgaaaaact tactgctgct gatatagctc atgaaaaaat tcaacatgtt
    17341 aatgatgtag tgactgatga acaggctatt gctaataact atatatatga gcatacaagt
    17401 aaaaatggaa ataagacaat gcttgcatcc actccagtta aatttggaaa tattgaagtt
    17461 aacatgactt gtgatgctcc acttatagga gaacattcag atgagatatt gagagaactt
    17521 ggatacagtg attctgatat agaagctcta attgaatctg gaattgtaac aatgaataaa
    17581 gaagcatgtg aaatatgtta ataaacatgt gaagtatgtt aataaatagg agggaatttt
    17641 atggatttta gattaacaga agcacaatta atgcttcaaa gagtagcaaa agaatttgca
    17701 gagaatgaaa tagcaccaat agctgctgaa acagataaaa caggtatttt tccaagggag
    17761 ctttttagca aaatggctaa aataggattt aatggcattg gaacacctgt agagtatagt
    17821 ggttctggag ggacagatat agaaaaggta attgttgtta ctgagattgc caaaaaatgt
    17881 gcagcatctg cagcaatatt atcaatacac acaatatatg ctcaagctat tttgaaattt
    17941 ggtactgagg aacaaaagaa aaaatacctt ccaatgatgg ctgaaggtgg gtgtgtaggt
    18001 gcttttgcct taaccgaacc taacgctggt tcagatgctg caagagctgc gacaactgca
    18061 attattgatg aagaaactga tgaatatgtt ttaaatggaa ctaagtgttt tatttctggt
    18121 ggaggtcaag cagaatcatt aataatattt gcactgacag acccatcaaa aggaataaag
    18181 ggaatgtctg ctatcattgt cgacaaaggt actccaggtt tttcaatagg aaaaattgaa
    18241 gaaaaaatgg gtattcatgg ttcagaaact gcagagttaa tatttgataa ctgtagagtt
    18301 ccaaagtcta acttattagg aaaagaaggc aaaggattta atatagctat gacttgttta
    18361 gatggagcaa gaattggagt tggagctcaa gctgtaggaa ttgctgaagg ggctttagaa
    18421 gaaagtatca aatattctaa agaaagagtc cagtttggca agccaatttc agctttgcaa
    18481 ggtattcaat ggtatatagc agatatggtg acaatggtgg aatcagcaaa attattagta
    18541 tattatgctg cagatttgaa agctagagga gaaaaacaca ctaaagaagc tgctatggca
    18601 aaatacaatg cgtcaagtac tgcaagagag gttacaaatc tagcccttca aatccatggt
    18661 ggatatggat atatgaagga ttatccatta gagagaatgt acagagatgc caaaataaca
    18721 gaaatttacg aaggtacttc agaaatacac aaagttgtta tttcaagagc agtactagga
    18781 taggaggaaa agaatgaata tagttgtttg cttaaagcaa gttccagata ctaatgaagt
    18841 taaaataaat aaagagacag gtactctaat aagagatggt gtaccaagta taatcaatcc
    18901 agatgataga aatgctttag aagaagctct aaaaatgaaa gatgaactag gagcagtgat
    18961 taaggttata agcatgggac ctcctcaagc taaaagtgct ttaaaagaag ctttggcaat
    19021 gggagctgat gaagcttatt taatctcaga tagagctttt ggtggttcag atacttgggc
    19081 tacatctaca attattgctg ctgctataga aaaggttgga aagtatgatg taatattctg
    19141 cggaagacaa gctatagatg gagatacagc tcaggttgga ccagaggttg cagaattttt
    19201 agggatacca caagttactt atgcaaaaga agtaaaggtt caagatgaca aattactagt
    19261 aactcgttat acagagacag gggattattt aatagaagca aagatgccag ttttattaac
    19321 tgctataaaa gagttaaaca atccaagata tccaagtgta aaaggaatct tagaagctta
    19381 taataatgga gatgcgaaga ttactgtatt aacacttgca gatttagatg ttgatacaac
    19441 tcaaattgga ttaaagggtt cacctacaaa tgtttataag tcttttgtac cagttaaaga
    19501 caagcataat gaaataatag aaggtataaa taaaaaagaa aaagctgaga aactaataga
    19561 aatactattc gatttgaaac tagtatagga gtgttaagat gatgagagca aaagttaatc
    19621 aaggtataaa tttaaatgat tataatggtg tttgggtaat aggggagcaa agggaaggca
    19681 aaattaatcc tgttacgata gaacttattg gtgaaggaag aaagcttgct gaccaattag
    19741 gaaaagagct tgcagttgtg atagctggat atgaagtaga gaaagaagtg aaggaattac
    19801 ttcactatag tattgataaa gtatattaca tcaatgaccc tcttcttaaa gatttcacta
    19861 ctgatggata ttcaatttca attgcaaatt taatcgaaag aaaaaagcca gaggttgtat
    19921 tggttggtgc tacttctata ggaagagata tagcgcctag aattgcaggt aaggttggaa
    19981 caggtctaac tgctgactgt acaaaacttg aaatagattc aacagataat aagttattac
    20041 aaacaagacc agcatttggt ggaaatttaa tggccactat tgtttgtcca aaaaatagac
    20101 cacagatgtc aacagttcgt ccaggggtta tggcaaaagc tgtaagaaac gaatcagaga
    20161 ctggaatttt agaagttgtt actccagaac ttactgaaaa aatgattaga actagattag
    20221 tagagatact tccacaagaa aagaaatctg taaatctaac tgatgctaga ataatagtat
    20281 caggaggaag aggattaaaa agagcagaag gatttgagct tataaaagaa ttggctgata
    20341 aattgggggc agagattggt gcttcaagag cagcagtaga ttcagggtgg atagaacatt
    20401 ctcatcaagt gggacaaaca ggaactactg ttagaccaga actatacatt gcatgtggaa
    20461 tatctggagc aatacaacac ttagcaggta tgagtgattc taaatatata gttgctataa
    20521 ataaagatgc aaaagcccct atttttagta tatgtgacta tggaatagta ggagatttat
    20581 atgaaattat acctgaaatg atagaatcat taaataggta acttttagaa aacattgaat
    20641 atgtagaatg ataagtctta taatattgta ttgtaagact tattattttt gctgaaggtt
    20701 atagtgggga gatgaaacaa tgaaagagca gtggtataag gatatatttg caagagtatt
    20761 atctatgact gatgatggtt ttattgttgt aaatacaagt ggagtaataa tagatattaa
    20821 tgataaatat tgtgactttt taggaaaaga aagaaaagat ataataggac aaaatataca
    20881 aagtattata ccaaatacaa aaatgctaga tgttatgaaa gataagtact gtgaagaagg
    20941 agctatacat cattattcag gtggaaatac aaaagaaaaa agtgtaatag taagtaggtc
    21001 ttatgtggaa aatgacaatg gagaagtagt tgcaggagta gctcaagtta aatttagatt
    21061 gcaatcattt gatgtagcta aaaagttaat gtcagaatat atggagctcc aatattataa
    21121 agagcagttt aaggataact gtggttttga caagctcata ggtgaaaata gagacttcat
    21181 agaacttaag aaaacaggtg tgaaagcttc taaaacaaac tttccagtac ttttaacggg
    21241 tgaaacaggc acaggtaaag aagtctttgc tagagcaatt cacaataata gcagtaggtc
    21301 agataaacct atggttagta taaactgcgc tgcaatacca gaagaattat tagagtcaga
    21361 gctatttggt tatgacgaag gagcttttac aggagcaaaa aagggtggta aaaaaggtaa
    21421 gtttttagtt gcaaataatg gtacaatctt tttagacgag ataggtgaca tgcctttgac
    21481 catgcaagca aaacttttaa gggttcttca ggaaagtgag atagaaccag taggaggtct
    21541 taaaactata aagatagatg taagagtaat ctctgccaca agaaagaatt taagtaaaat
    21601 ggttgaagag ggattattta gagaagacct atactataga ttaaatgtaa taaacattca
    21661 tatgatggaa ttgaaggaca ggcaagatga tattttattg ctagcaaatt atatattaaa
    21721 caaattaaat gttgaataca aggaattgaa ggttttaagt gataaggtta aaaattgttt
    21781 tattaactat acttggccgg gaaatataag agaactacaa aatgtaataa aaagtgccta
    21841 tgctgtaagt gatgatatgg tcattatgat gtgtgacctt ccatctaaga tggataatat
    21901 cagcagagta gctcaatgta atgtggatag caattgttca attcatgaaa tggttgagaa
    21961 ttatgaaaaa agcttaatta ttgatgtgtt aaggaagtat aattggaaat gttctaaggc
    22021 agcagaggtt atgggaatac acaagagtct tttatataag aaaataaaaa agtatgaaat
    22081 tgaattaaat aattaagata acttgaatta aggcaatgct aaaaaaagcg cccttattca
    22141 aagcgaactg tataaactgt tttatgcagt taaaacgtgt aaaagtagat gtgaagtact
    22201 aatgtcaatc attagtactt tttattgtat ttataattac tatctatatt tcagtatctt
    22261 ttgatatcta agattattat gtttaattta ggatataaca aaaccctctt agttattgac
    22321 agttttttat attttaactg tctactaaga ggggatagtt tagtttaaat ttagagtaaa
    22381 ttttatctag catttataaa aaatattttg aatagctttt ttgttattta gtcataattt
    22441 tctacttctt tatcaagttc tttgccacaa gaatcacact tatatatagc attgtatcca
    22501 taatcatatt catcaactat tttcttttgt ctaaatacac caccacactc acataggaaa
    22561 ccaattttta taagtgtaac gataaattgt gattttataa attttatatc attacattta
    22621 tcgttagtgt aaaatgtata aatataagag ttatcgcact catctcttaa ttcaaatctt
    22681 tcaatatatg tgttattttt taattcctca aattcttctt tagttaaata tgatttttgt
    22741 tgcaattcat gtaaacgctt aatttggtcc attatttata tcctcccaat aattttagta
    22801 ttttaagctt agataaggaa tctaagtttt attaaattta tcccaaggaa ttatttaaat
    22861 catatttagt tttattaaat acaacatata taaattacac gaaaataaaa ctaattgtaa
    22921 aaataatatc ctgtgaaaac ctaaactact aaccccttac taacccgaaa actaaaaaaa
    22981 gaaaatatat ccaaatataa gtgatatata aataaagatg ttttatataa atttaacttt
    23041 aaatattctg acaataatat atataaatat attatagtta aaatatacca catattttgg
    23101 gtattgtata ctggaattag agtaattaat ttatttttta acatacaaat gattttatga
    23161 aaaaaaacaa gactcaaaaa tttttatatt ctttgataga ataaaattga gagtaaattt
    23221 attgaatttt ataaaattta taaggggtga gtctaagata tgcatgaaga taaaaatgat
    23281 atatttgaat caatagatac tgaggatttt gataataaaa cagaagaaga atgtttagag
    23341 ctagtaagaa aaaatggatt gaatttaata tacataaaaa atcaaacaga agagatatgt
    23401 ctagaggctg ttagacaaaa ttgtaatgca ataaaatgtg ttcagaatca gacagaaaaa
    23461 atatgtatag aagcagttaa acaagattgg agaatgttag aatttgtgga agagtcaaca
    23521 gaagaaattt gcatgttggc tattaaccaa gatggaacag cattaaaata tatagaaaat
    23581 cagacagagg agttatgctt aagagccgtt gaaaaaaatg gtgcggcttt ggagtatgta
    23641 aaagaacaaa cagaagaaat atgtatagaa gcagttagaa acagcgaatt tggattggca
    23701 agagtgaaaa atcaaacaga aaaaatatgt atggaagcag ttaagcattg tagctataat
    23761 ctaaaatggg tagaaaatca aacagaagaa atatgtatgg aagcagtgag acaaaatggg
    23821 cttgatttga aatttgtaaa aaatcaaaca gaaacaatct gtttaagagc agtaagacaa
    23881 aatggaatgg cattagaatt tgtaaaggaa cagactgttg gtatatgctt aaaggcagta
    23941 agacaatatg gaatggcatt aaaatttgta aaagaacaaa cagaagaaat ttgtacagaa
    24001 gctataaaac aagataaaag agcacttagt tttgtaaaag gagataagga aaaatacaag
    24061 gctctatatg ataataatga accatttgca aagagatatg ttagaaatgt aatagaaaaa
    24121 gaaaacagag cattgattaa aaaaggagaa gaaaatgcaa aaatcaaaat tgcaggaaaa
    24181 ctttatgata gaggcatgtc ttttgaagat atatcagata tagttgagat tgaaataagc
    24241 aagttaaaag tgagtttagg tgttttttaa agtaataaat gtaggtgttt tttatgggaa
    24301 atagttaata aaaaaataat cgactagctc tttgtaggac agcaaaatta gtgatataat
    24361 ttgatgtata ataaattatt tttattagat aagggggaat taaagttgaa gattacagta
    24421 ttataccaaa caagaagtgg aaacacagaa agggtcgcta agctgataga agatggagct
    24481 aaaaaggtgg atggagtaga tgtaaagctt atgagacttg ataatattga tttagattat
    24541 ttaaatgaaa gtaaagcagt aatatttgga acacctactt atttagcaaa tacaacttgg
    24601 gaagtaaaaa aatggtttga tgaagattca aaaaaagtta atttagctgg aaaattagga
    24661 gctgtttttg ctacatgtga ttatatatgt ggaggtccag atgttgcgat acttactata
    24721 gtaggacatt tgatggttaa agggatgctt gtgtattctg gaggtggttc tttaggaaag
    24781 ccatttatac atttaggaca tgtacattca attgaaggtc cagagttaca agatgagaag
    24841 gctataatat ttggtgaaag aattgctact aaggcaaaag aactatttgc ttaatttcta
    24901 tatgcataat aatgattaga gtaaatttag ggttttaatg gagatttgaa gtaaaagtta
    24961 taaaata
//
LOCUS       DACTZW010000063        24911 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.063, whole genome shotgun sequence.
ACCESSION   DACTZW010000063 DACTZW010000000
VERSION     DACTZW010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24911)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24911)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24911
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.063"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            <1..227
                     /locus_tag="JAM15_13085"
     CDS             <1..227
                     /locus_tag="JAM15_13085"
                     /inference="COORDINATES: protein motif:HMM:NF025063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAT6799188.1"
                     /translation="NGIIQSMSRRGNCWDNAPIESFFSHFKSELIYLIDTTDPKEMIS
                     LINDYIYFYNNERIQLKNGMSPIEYRTHSA"
     gene            complement(326..1468)
                     /locus_tag="JAM15_13090"
     CDS             complement(326..1468)
                     /locus_tag="JAM15_13090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAT6799189.1"
                     /translation="MDFKIEKYLLKKAEELAFITIKHGGEFKLKSYKVPKGGLDVPIK
                     NEVLVKGIKEKTAQDKLNSMSIADAMIYIIGIDSKFKNNAEYEKFLNALSKDIDLDLK
                     SYMGYMSRKYFEIGEHTDSLIYIKAFITMYPDDLDAMYNYAIVCQEIAKQYQKDMDDK
                     AMNAFLLEAMAKLEKVIDVDENFALGYYHLGYHYYNQGQYLKTKLTWEDALRLGLDAD
                     LVAEIQDNLGKMDFKVQYEEGYTLVFQGKFKEGLEKLLPLEEEHMDWWNLLFMIALGY
                     KGMGEIEQAEMYLEKILIIKPEQVDAIVELGLCEAYKNNLDKAIEYFEQAAKIKEDPE
                     ILCNLGMAYLNNGDIDDATYYIERAYELNPQDEITIACLRELGINK"
     gene            complement(1486..3240)
                     /locus_tag="JAM15_13095"
     CDS             complement(1486..3240)
                     /locus_tag="JAM15_13095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B12-binding domain-containing radical SAM
                     protein"
                     /protein_id="HAT6799190.1"
                     /translation="MKILLTTLNSKFIHTNLAIRYLKEFVRDLIEVNMKEYTINNDLD
                     YILKDIYKNEYDIILFSTYIWNVGDIVKLCDNLKKIRPNTKIALGGPEVSYDSYEAMK
                     KYDFVDYILYGEGELIFRDLVLHLQGKMKINDVNGLVYRQGNEIIVNKPMELLQDLDE
                     IPSPYENLNPKEYENRIVYYESSRGCPFNCQYCLSSTIPGLRYFSLDRIKSDLKALID
                     ARVSQIKFIDRTFNANRKVAMEIMDFLMKNDNGYTTYHFEVTAYLIDDKMLEFLADCK
                     EGLFQFEIGVQSTNEKTLDAVGRRDDFKKLSHVVQTVASYRNIHQHLDLIAGLPYEDY
                     KSFENSFNDVFNLGIEHLQLGFLKMIKGTGMRKVADEHGFKYKDYAPYEFLYNNYISY
                     EETLKLKDIEDILERYYNSKNFVLSMRYIIGRFYKQSPFKFFEVFAKYFDENGYFDLA
                     QGKNQLYKILMDFYNEKINIDNDVFNDILKYDYISLGKTSNIPQFFNKLDVDDFKNRC
                     HVFLQDNDNLSTYLPSFVDKPAKHIIKYVHFEPFRFNVVDLKNDINTEIREVENVVLF
                     EYDDKKIFEKSKTHKVEI"
     gene            3376..3582
                     /locus_tag="JAM15_13100"
     CDS             3376..3582
                     /locus_tag="JAM15_13100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799191.1"
                     /translation="MELIEKVSINSLSKRDLLLIIKSLEYTNENTQISDFIDLRNNIV
                     KELCFLTDTKEKDFLDYLEKNSTL"
     gene            complement(3587..4510)
                     /locus_tag="JAM15_13105"
     CDS             complement(3587..4510)
                     /locus_tag="JAM15_13105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799192.1"
                     /translation="MNDELLKKVYTSSFSSASRALKDLTIINTKSLIDDKTQRCVYID
                     ENRLRDELIYYRFYGEKIGNINFLNILLPLILSNTNIQKSEDEVIKLIKKYVIYFKKE
                     ELLFDYLLGSVVYNSIMHNLINNSKIEYVELLQSIKDKIIGFSIELDKSDVVKFQMAR
                     IKAIQLIDKYIDLKSEDYDEESILLNVLNVLYDVYMEDRTVENEGINSIKKSILSILG
                     EDSKLNEDNIDFIFSMSEYVVKLRKYKIGVKAYNKSIDPRSLIRLEEGNTIIDPIFNQ
                     ITVMSKTFNDNILSIKINSKSGIYILKFKKV"
     gene            complement(4763..6463)
                     /locus_tag="JAM15_13110"
     CDS             complement(4763..6463)
                     /locus_tag="JAM15_13110"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007286376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HAT6799193.1"
                     /translation="MQDFKVAISNCLKEKIEDLSKEEIEALIEVPPNKDMGDYAFPCF
                     KLAKVFRKAPNMIASELAESIEPSGEITKVIQLGGYVNFFVNKSQLAETVIKKVLDEK
                     ENYGHSDFGKDKTVIVEYSSPNIAKPFHIGHIRTTVIGNALYKIYDSQGYKTIRINHL
                     GDYGTQFGKLIVAFKKWGEKEVVESNPIPELLKLYVRFHDEAEQHPEMEDEARAWFNK
                     LENGDEEAQELWQWFRNESLKEFNRVYKLLDIEFDSLAGESFYSDKMNRVIELLEEKN
                     LLKESKGARIVDLEEYKMPPALITKNDGSTLYMTRDLAAAIYRKETYDFDKCIYVVGS
                     QQNLHFQQWFKVIELMGYDWAKDLIHVGFGMVALEEGTMSTRKGRVVFLEDALNQAID
                     KTKEIILAKNPNAKNVDEISKQVGVGAVVFQELSNSRIKDYTFSWERTLSFDGETGPY
                     VQYTHARCCAVLRKAEVEVTSDIDYSLLADEDSAEVLRVIESFNKNILLALKKNEPHI
                     VTRFMLDLAQAFNKFYHDNPILVENLEIRKARLALVLATKQTLENSLKLLGMHAPERM
                     "
     gene            complement(6824..7237)
                     /locus_tag="JAM15_13115"
     CDS             complement(6824..7237)
                     /locus_tag="JAM15_13115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HAT6799194.1"
                     /translation="MILVSACLIGINCKYSGDNNENEKVKEYLKGKEFTLVCPEQLGG
                     LSTPRPPAEIVDGKVITKDNKDVTENFVRGANETLKIANLYVCSEAILKEGSPSCGCN
                     LIYDGSFSGKKIPGKGITARLLEEEGIKVKSEKDL"
     gene            complement(7305..9683)
                     /locus_tag="JAM15_13120"
     CDS             complement(7305..9683)
                     /locus_tag="JAM15_13120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HAT6799195.1"
                     /translation="MNEKSLRVLEYNKIIDLLKKKASSSLGLKYIENLVPNTDFVEVK
                     SMLEETSEAQSIIIKRGSVGLEGIHDIEDKVKRAYIGASLDPGSLIMIADTLRVARRL
                     RNSLSSSDEEDFNYPIIQSLSNSLYVYKDIEDQIYNAIISEVEISDNASSTLRDIRRR
                     IAQKNQSIRSKLNSIISSTTYQKYLQDAIISLRGDRFVVPVKSEYRSQVAGIVHDQSS
                     SGATLFIEPMTIVEMNNELRQLKLGEQEEIERILSELSAMVGKVSEDLISNQEILGRL
                     DFAFSKGKLSIQMRGIEPTLNEDKYLNIKNGRHPLLDKKKVVANTIYLGRDFHTLVIT
                     GPNTGGKTVTIKTVGLFALMTQSGLHIPADYGSSMCVYDNVFADIGDEQSIEQSLSTF
                     SSHMTNIVSILQNVTADSLVIFDELGAGTDPVEGAALAIAVLEDINSVGAKCIATTHY
                     SELKNYALTKPGVENAAVEFDIETLSPTYKLLIGVPGKSNAFEISRKLGLSDYVISRA
                     KEYINTENIALEDVLQNVEKNRIKAVEDREEAERLKEEIEKLKVEYDEKLEKLVSQRD
                     KMIEKAKSEAFSIIRQAKEEVDIIIKELRNLEQERASKEKNRKIEELRKELTSSMGSL
                     QPTVKSMIVPKVSNKEIKDLKPGEEVKVITLNQNGSVVSVDKKRKEAVVQIGIMKMTL
                     PFKSLQKTRKDVSTNVTKSTRNIIRSKSGSVKNEVDLRGLNLEEAIMEVEKYLDDAYV
                     AGLESVTVIHGIGTGVLKAGLQDILRRNRHVKSQRGGQYGEGGAGVTIVKLK"
     gene            10001..11452
                     /locus_tag="JAM15_13125"
     CDS             10001..11452
                     /locus_tag="JAM15_13125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-histidine dipeptidase"
                     /protein_id="HAT6799196.1"
                     /translation="MGNVLEGLKPESVFKNFEKISQIPRGSGNEKGISDFLLSFGKNL
                     GLETIQDESLNIIIRKPATKGYENCPGVVLQGHMDMVCEKEKNVEHDFLKDPIKLRID
                     GDMIYATGTTLGADNGIAVAMGMAILEDNTLEHPALEVLVTVNEEDGMNGADALDPSL
                     IKGQYILNMDSEEEGYLLVSCAGGKTCVVSLPVEYKKVEGDKQGLLVEVTGLLGGHSG
                     MEIVLQRANANKAIARVLSVLNVDYELASVDGGTKHNAIPREAKCVIAVNKADVESAK
                     KQINDILTAFKHEFTTSDPGMTYSVAETSVDKVLTKDCKEKVVQMSCLTPHGVQSVSL
                     DIEGLVESSTNFAIIETKESTIEFLTSVRSSVMSIRDEIADRIRLLAQALGANYDLIA
                     QYPAWEFKKGSKLEKICSETYEKLTGKVPTVMALHAGLECGLLLDKLPHAEAISIGPD
                     MFDVHTPNEHVSIPSVANVWDYVIEILKSMNQY"
     gene            complement(11656..14169)
                     /locus_tag="JAM15_13130"
     CDS             complement(11656..14169)
                     /locus_tag="JAM15_13130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HAT6799197.1"
                     /translation="MEDCVVNLKKLLLLIIVITSIFTSCIFSFGINAIGNDNRTIRVA
                     YPIQKGLTEIDEQGNYFGYTYEYLLEIAQYTGWNYEFVQVPGEINESITKLMKMLENG
                     EIDIMGGMLYNEPMQKIYNYAGNSYGVANTVLQALYENTDIDNIMSSQDVKKIRIAVI
                     ENSDTRLKELDEYCKMNLMSPELVYCKTSDEQLEVLKSGKADVLLNVSMNPIEGVRTV
                     AKFSSKPFYFITPKGSTDLTQKLNSAINNIEQKDPYFSTTLYEKYFTPENNQMFLSDE
                     ETNYIKDTEKLKVGVLLNKPPFQNADKDTGELRGISIDLLNHICDKTGLEFELVPVKS
                     QEDLEDMAKKHEIDIVAGMIYDYEYSREHNIAMSRPFLSTQYTMMINNKLNENSLNGK
                     RIALAKGIDYYGQFEENIVWYDNLEECIEAVNKGYADYTYGEGYSMQYYMNQPKYKNV
                     RLVPQTYEAKSICFGIIKKDKQELLNIFNKAIISISSEKMQSIVYQNTTYRQDFSLLY
                     IMQQNPIETIFIVASLLICIIGFMAFGLHTRTSMNEKISLELKKHTQLYEMTSEYFFE
                     YDYKQDKLIISMPEKGIETYYGLDKSDKESENGNIENERDKIRREYNKKFFDVIKSQE
                     NGTTEMYSIMLDDTFHWIRITSKIIYNDRKIPMYVIGKIANIDSEKEEKNRLLDKVQR
                     DSLTNIYNAAYIRKLTTQNLLNLSTEKNGALLIIDIDYFKSINDTYGHLVGDKVLIDV
                     AKVLDESFAKDDIVGRLGGDEFSVYINDIINKEELINKCNDVYNHIHLIKLPNGESLS
                     ISMGVVITKRGQEYDELYQIADNALYDSKRQGRNRFKIV"
     gene            complement(14392..15213)
                     /locus_tag="JAM15_13135"
     CDS             complement(14392..15213)
                     /locus_tag="JAM15_13135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HAT6799198.1"
                     /translation="MIDINLEKCVGCGMCESDCLVNAIKVKDDKAKVKNILCINCGHC
                     MAICPTDAIEMQGFDKNEVIEYNRESFELEPEKLLNFIKFRRSIRQYKDIEVEEEKIK
                     KIVEAGRYTPTGGNRQPIRYILVKEKLKEVKELAIQGLYNLALDTDDNDPVRSIYKNT
                     FKKMYKRYKENGNDSLFYDAPLLMIVVGDMSLGGSAYVDGGLAASNMELMAYSQGLGI
                     CYNGFFVMASNVEPKIKELLGMSENEAVITSFILGYPDVKYKRTVNRNTAKFEMR"
     gene            complement(15731..16207)
                     /locus_tag="JAM15_13140"
     CDS             complement(15731..16207)
                     /locus_tag="JAM15_13140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HAT6799199.1"
                     /translation="MKLTTICYIEKDDKTLMLYRNKKKDDIHEGKYVGVGGKFEQGET
                     PEECVIREVKEETGLTLKSLTYKGLITFPKFKDEEDWYMFLYFSDEFEGELSEKDLND
                     CKEGNLIWVDNDKIFDLNMWEGDRLFLNWAKTGNIFSAKIVYDNGKLKDYNVSFLD"
     gene            complement(16241..16819)
                     /locus_tag="JAM15_13145"
     CDS             complement(16241..16819)
                     /locus_tag="JAM15_13145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAT6799200.1"
                     /translation="MREEALEILFKYLETDRMRKHCYAVEAVMRELAKRLEPEKEEEW
                     AVAGLLHDLDSDIVGRKPGEICEGHATTTVELLKKENFGDEEMYRAILGHHDGMGVTR
                     TSLMEKAIYAADPITGFITAIALVYPDKKLTSVKTKSVIKRMKETRFASNVNRDAMRS
                     IEDIGIPFDEFAELSLNAMKNISDVLESAENN"
     gene            complement(16923..19505)
                     /locus_tag="JAM15_13150"
     CDS             complement(16923..19505)
                     /locus_tag="JAM15_13150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HAT6799201.1"
                     /translation="MKKIELLAPVGSFDSLKAAVQNGANAVYLGGKDFSARASANNFD
                     RNELIDAVKYSHIRGVQVFVTVNTLIKQYEIEDFVEYVKFLYDIDIDALIVQDIGMAR
                     LIKKLLPDFELHASTQMVAHSLEDVKYLQSVGFDRVVLARELNVDEIKWICENTTVDI
                     EVFVHGALCVCYSGQCLMSSMIGNRSGNRGRCAQPCRQKYELIDINTGEVVKSDGDYL
                     LSPRDLSTIEELDKIIEAGVLSLKIEGRMKKPEYVATVVSGYREAINEFVDKNKISIS
                     DEIINNLYTIFNRKFTKGYILGEVGKDVMNSNRPNNQGLYVGKVLDYNRRSKRLRVIL
                     ENTLKKGDGINLGGGTIGRIIKDGEITTIAHKGDLIELDFVGEAKRNQLIFKTSDSEL
                     MDRVQATFQQDKELIKTNIRAKVSIKLGKKPELFISDFCGNKSVVEGEKIVEKAIKVA
                     LSKEKIETQIQKLGNTPYKLKEIEIDLDEGVSMPISVLNQMRRDCIELLDEERIKIKG
                     RKFKKNRLKYQPNRVNKQKKLDTVPKIRVKVKNLEQLEAVLNYNVDLIYYEDINTLSK
                     ALQMVSSISIDSSISMDLDTYSSLGIPKELMGSNTNNIDTLSNTSKIDTLNKNHSNIV
                     VTDKKLIYSAPRIIRNKEYKQFEILDNIKGINKVQIGNWGSMEYFKKKDLNIDCYLNA
                     FNSESINHFKEEGASTVCLSQELNLNEIKQTLKYTDVEIEAVIYGYAPMMVTEYCPMG
                     VVVRDCKKDKRVAKCKESSYALRDFTDASYRITQDIFCRSTIYNSKVTCMLDNLYELE
                     EIGIDVFRIDFTVEDSEMVKKVIEAHIEVLSNNYKLGKKATDLYKKLDEIGTVAGHYY
                     KGVE"
     gene            complement(19665..20345)
                     /locus_tag="JAM15_13155"
     CDS             complement(19665..20345)
                     /locus_tag="JAM15_13155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HAT6799202.1"
                     /translation="MTSQSQMSESFFLCSLLAITGGFLDIYTYVVRGKVFANAQTGNI
                     VLLGLNIAEGNIKKSFYYLIPILAFMLGVFIAEKIRKYFKDNSKIHWRQVIIIIEMIT
                     ILVVSFVPRGQFNMFVNVAISFICSMQVESFRKVNGNSFATTMCTGNLRSATETLFHY
                     IQTKNIFMIKKSLQYYAIIVFFISGAILGTFFTKIFVEKSILVCFFILAVVFGVMFIN
                     KDDSFNEN"
     gene            complement(20507..21097)
                     /gene="zapA"
                     /locus_tag="JAM15_13160"
     CDS             complement(20507..21097)
                     /gene="zapA"
                     /locus_tag="JAM15_13160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HAT6799203.1"
                     /translation="MNKVMVKIHGAEYPMVGDKSEKFMISIADFVDKEMDKITRQNPK
                     LSLSVAAILTALNISDLLFECSDENEKLIKANEELSKKVGASNEELQLEIKSLKLTIA
                     EKEAESRETEAKMKELIDIIENKKQEIFELSNTTEGSRAELDAYKSKIEELSAQLEEA
                     NERATIAENLASEFQNKAYDLQLKCTGLNNDEKNVK"
     gene            complement(21122..23515)
                     /locus_tag="JAM15_13165"
     CDS             complement(21122..23515)
                     /locus_tag="JAM15_13165"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HAT6799204.1"
                     /translation="MLVSLKWLRDYVDIDMDVKEFADKMTMTGTKVETIDYYGEEIEN
                     ILVGKILEIKQHPNADKLVVTKVDIGDKVVQIVTGATNISEGDYIPVAINGSKLPGGV
                     EIKQTDFRGELSDGMMCSAAELGIDEHYIEEYKRGGIYILDHEDSYELGKDIKDVLGL
                     KDALIDFELTSNRPDCKCMMGIAREAAATIGTKVKYPEIKVKESDEEIDFKVEIDNPD
                     LCRRYVARMVTDVKIEPSPYWMQRRLTEAGVRPISNIVDITNFVMLELGQPLHAFDIN
                     QVETGRIVVRNAKDGEKLVTLDDVERTLDKDMLVITNGEKSLGLAGVMGGANSEITSN
                     TKTVLFESANFKPENIRMTAKKVGIRSEASSRNEKDLDPNLAEIAANRAAQLVEMLGA
                     GKVLKGVVDVYPNKPEPKKLVVNPQRINHLLGVDVPMEQFVGILESLEFKCNLVANDK
                     LEIDVPSFRTDMEQEADVWEEIARIYGFENIPSVQLEGNTTAGIKTSKQKFMDALKDN
                     STAVGLNEILTYSFVSPKGVDKIRVPEGNAKRNFVKLLNPLGEETSVMRTTLIPNMLD
                     VLSTNVSHKIEEVSAFECGHIFIPQDSELPKEENRMCVGMYGKDVDFFALKGTIETIL
                     VNVGFKGYEIEPQDNNTTFHPGRCAKIVYNNKYVGTLGELHPDVIENYNLGQRVYVAE
                     IDIDFVFDNSDRTKNYVPLPKYPSTSRDIALIVKDDVFVKQIEDIIKENGQGLVESYK
                     LFDVYKGSQIEAGYKSIAYSITYRSKDKTLTDEDVAKVHDKILSELSEKLNANLRSN"
     gene            complement(23532..24551)
                     /gene="pheS"
                     /locus_tag="JAM15_13170"
     CDS             complement(23532..24551)
                     /gene="pheS"
                     /locus_tag="JAM15_13170"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002842815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HAT6799205.1"
                     /translation="MQEKLLALREAALAEIKEAQSIESVESLRVKYLGKKGEITAILK
                     EMGKLSAEERPVVGKVANEVRENIELSINSKKEEINAIEKERKLKEEVIDVTQPGKVL
                     KVGKKHPITQIIDEVTDIFIGMGFSIAEGPEVETVENNFDALNAPKDHPSRDMSDTFY
                     INDGVLLRTQTSPVQVRTMRSQELPIKVIAPGRCFRSDSPDATHSPMFHQIEGLVVGK
                     DVTMAEFKGTMDIFVEKLFGSDIKTKFRPHNFPFTEPSAEVDVTCFKCGGKGCPMCKY
                     EGWIEILGSGMVHPNVLRNCGIDPEVYSGFAFGVGVERLAMLKYEIDDIRLLFENDMR
                     FLNQF"
     misc_binding    complement(24601..24835)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
BASE COUNT         7717 a         4608 c         2731 g         9855 t
ORIGIN      
        1 ataatggtat tatacaatct atgtcccgaa ggggcaactg ctgggataat gctcctatag
       61 aaagtttttt cagtcatttt aaatctgaat taatatattt aattgatact acagatccaa
      121 aggaaatgat tagtctaata aatgattata tttattttta taataatgaa agaatacaat
      181 taaaaaacgg aatgagtccg attgaatatc gaactcattc cgcataaaga tagccttttt
      241 taagtctgtc tacttgacag ggacatatcc aattttgaga tagccccact taaccgataa
      301 aattaaatac aacctaacaa tatccttact tatttattcc aagttctctt agacaagcaa
      361 tagtaatttc atcttgtgga tttaattcat aagctctttc tatataataa gttgcatcat
      421 caatatcacc attatttaaa taagccatcc ctaaattaca aagtatctct gggtcttcct
      481 ttatcttagc agcttgttca aaatattcta ttgctttatc taaattattt ttataagcct
      541 cacaaagccc taattccact atagcatcca cttgctcagg ctttattatc aatatcttct
      601 ccaaatacat ctcagcctgt tctatctcgc ccataccctt atatccaagt gctatcatga
      661 acaacaagtt ccaccaatcc atatgttctt cttctaatgg cagtagtttc tctaatcctt
      721 ctttaaattt accttggaat acaagcgtat atccttcttc atactgaact ttaaagtcca
      781 tctttcctaa gttatcttgt atctcagcta ccaaatcagc atctagccca agtcttaatg
      841 catcttccca agttagctta gtctttagat attgaccttg attataataa tggtagccta
      901 agtgataata acctaatgca aaattctcat caacatcaat taccttttca agcttagcca
      961 tggcttcaag taagaatgca ttcattgcct tatcatccat atctttttga tactgtttag
     1021 ctatctcttg gcaaacaatc gcatagttat acattgcatc taaatcatct ggatacattg
     1081 ttataaatgc ttttatatat attaaagaat ctgtatgttc accaatctca aagtattttc
     1141 tcgacatata tcccatatac gatttcaaat ccaaatcaat atcttttgat aaagcattta
     1201 aaaacttctc atactctgca ttgtttttaa acttactatc tattccaatt atatatatca
     1261 ttgcatctgc tatagacatt gaatttaact tatcttgagc agtcttttct tttatccctt
     1321 ttactaatac ctcatttttt ataggtacat ctaatccacc ttttggcact ttatagcttt
     1381 ttaatttaaa ctctccacca tgttttatag ttataaaagc taattcttct gcttttttta
     1441 gcaaatattt ttctatctta aaatccattt tatcctccta aatacttaaa tctctacttt
     1501 atgagtttta gatttctcaa atattttttt atcatcatac tcaaataaga ctacattttc
     1561 tacttctctt atttctgtat ttatatcatt ttttaaatcc acaacattaa atctaaatgg
     1621 ctcaaaatga acatatttta ttatatgttt agctggttta tcaacaaaac taggtaaata
     1681 tgttgataag ttatcattat cttgtaaaaa tacatggcat ctattcttaa aatcatccac
     1741 atctagctta ttaaaaaact gtggtatatt tgatgtttta cccagtgata tatagtcata
     1801 ttttaatata tcattgaata catcattatc tatgttgatt ttttcattat agaaatccat
     1861 caatatttta tataactgat tctttccttg tgccaaatca aagtagccat tttcatcaaa
     1921 atacttggca aaaacctcaa agaatttaaa agggctttgt ttataaaatc tgcctataat
     1981 atatctcata gataacacaa agtttttaga attatagtat ctctccagta tatcttctat
     2041 atcctttagc ttcaaagttt cttcatagct tatataatta ttgtataaaa actcatatgg
     2101 agcataatcc ttatatttaa aaccatgctc atctgcaact tttctcatac ctgtcccttt
     2161 aatcatcttt aaaaagccta attgcagatg ctctatacct agattaaata catcattaaa
     2221 agaattttca aagctcttat aatcttcata aggcagtcct gcaattaagt ctaagtgctg
     2281 atgtatattt ctataagatg ctacagtttg tacaacatga gacaactttt taaaatcatc
     2341 ccttctacct actgcatcaa gtgttttttc attcgttgac tgaaccccta tttcaaattg
     2401 aaaaagacct tctttacaat cagccaaaaa ctcaagcatc ttatcatcta tcaaatacgc
     2461 tgtaacttca aaatgataag ttgtatatcc attatcattt ttcataagga aatccatgat
     2521 ttccatagcc acttttctat ttgcattgaa tgtcctatct ataaacttta tctgtgatac
     2581 tcttgcatct attaaagctt ttaaatcact ctttatcctg tctaaactaa aataccttag
     2641 acctggaata gtagatgata aacagtactg gcagttaaaa gggcaacctc ttgatgattc
     2701 ataatacact attctatttt catattcttt tggattcaag ttttcataag gactaggaat
     2761 ctcatccaaa tcttgaagta attccatagg cttattcact attatctcat tgccttgtct
     2821 atatacaagt ccatttacat catttatttt catctttcct tgcaagtgaa gtactaagtc
     2881 tctaaaaatt aattctccct ctccataaag tatataatcc acaaaatcat actttttcat
     2941 tgcctcataa ctatcataac tcacttccgg tccgcccaaa gctattttag tattaggtct
     3001 aatttttttt agattatcac aaagtttaac tatatctccc acattccaga tatatgttga
     3061 gaataatatt atatcatatt catttttata tatatccttt aaaatatagt ccaaatcgtt
     3121 gtttatcgtg tattctttca tattaacttc tatcaaatct cttacaaatt cttttagata
     3181 tcttatagcc aaatttgtat gaataaactt ggaatttaat gttgttaata aaattttcaa
     3241 atatttctca cctcttttta agattatact gtctttttgt accccttata ggttaaaata
     3301 gtatatgtaa agtctaaata atatctatat aattaattta ttaatttcaa gtaatgtgag
     3361 gaaaggaagt tttttatgga attaattgaa aaagtatcta tcaactcttt atcaaaaaga
     3421 gatttactac ttattataaa gtctcttgaa tacactaatg aaaatactca aattagtgat
     3481 ttcattgacc ttaggaataa tatagtaaag gaattatgtt ttttaactga cactaaggaa
     3541 aaagattttt tagattatct agaaaaaaat agcacactct aataacctaa acctttttaa
     3601 actttaatat ataaatacct gatttagaat ttatttttat gcttaatata ttatcattaa
     3661 aggttttcga cataactgtt atttgattaa atatagggtc tattatagta ttaccttctt
     3721 caagtcttat aagacttctt gggtctatgc ttttattata tgccttaact ccaattttat
     3781 attttctcaa tttaacaaca tattcggaca tagaaaaaat aaaatctata ttatcttcat
     3841 ttaatttact atcttcaccc aaaatggata atatagattt ttttatgcta ttaattcctt
     3901 cattttctac agttctatct tccatatata catcatatag aacatttaaa acatttaata
     3961 aaatactttc ttcatcataa tcttcagatt tcaaatcaat gtacttatca attaattgta
     4021 ttgctttaat ccttgccatc tgaaacttta caacatctga tttgtctaat tctatagaaa
     4081 atcctattat cttgtcttta atactctgta gtaattcgac atactctatt ttactattat
     4141 ttataagatt gtgcataatg gaattataca ctacagaacc taataaataa tcaaataaaa
     4201 gttcttcttt tttaaaataa ataacatact tttttattag tttaataacc tcatcttcgc
     4261 ttttttgaat attagtattt gataaaatta gtggtaataa aatatttaaa aaattgatat
     4321 ttcctatttt ttctccataa aatctatagt aaataagttc atctctcagt ctattttcgt
     4381 ctatatacac acatctttgc gttttatcat ctattaagga ttttgtattt attatagtta
     4441 aatctttaag agccctactt gcactactaa aagaagatgt gtagactttt tttagtaatt
     4501 cgtcattcat aaatatatcc tttctgaaaa attgaatgta aataaattgt tattaaaaaa
     4561 aaagagacag cccgtttaag aagctgtcat atataggggg atagtagtgt acaaaaatca
     4621 ttgtaatcta ctatctatat attattatac gatactactt tttatatgta aagcatcagt
     4681 tttcgacatc cctatatttt acagttatac aaattgcgta ctaagttcaa ttttattctt
     4741 tttatttcaa cattttatca tgctacattc tttccggagc gtgcattccc aacaatttca
     4801 gagaattttc taaagtttgt tttgttgcta aaactaatgc aagtcttgct tttcttattt
     4861 ccaaattttc tactaaaatt ggattgtcat gataaaattt attaaacgct tgagctaaat
     4921 ctaacataaa tctagtcact atatgtggct catttttctt tagagcaagt aaaatattct
     4981 tattgaatga ttctataact ctaagaactt ctgcactatc ttcatcagct aatagactat
     5041 aatctatatc agaagtcact tctacttctg cttttcttaa aactgcacag catctagcat
     5101 gtgtatactg aacatatggt ccagtctcac catcaaaact aagcgttctt tcccaagaga
     5161 aggtatagtc tttaattcta ctgttagata actcttggaa tactactgcc ccaacaccta
     5221 cttgcttaga tatttcatcc acatttttag catttgggtt tttagctagt ataatttcct
     5281 tagttttatc tatagcttga tttaaagcat cttctaaaaa tactactctt ccttttctag
     5341 tcgacatagt accttcttca agtgcaacca taccaaatcc aacatgaatt aaatcttttg
     5401 cccaatcata tcccataagc tcaattacct taaaccattg ttggaaatgt aagttttgtt
     5461 gagaaccaac tacatatata cacttgtcaa aatcataagt ctcttttcta tatattgcag
     5521 cagctaaatc tcttgtcata tataacgttg aaccatcatt cttagtaata agtgctggtg
     5581 gcattttata ctcttctaaa tcaacaattc ttgctccttt agactctttt aaaagatttt
     5641 tctcttctaa tagttcgata actctgttca ttttatcaga ataaaaactc tctcctgcta
     5701 aagaatcaaa ttctatatct aaaagtttat acactctgtt aaactctttt aaactctcat
     5761 ttctaaacca ttgccataat tcttgtgctt cttcgtcacc attttctaat ttattaaacc
     5821 atgctcttgc ttcatcttcc atttctgggt gttgttcagc ttcatcatgg aatcttacgt
     5881 ataattttag taattctgga attggattag actctactac ttctttttct ccccactttt
     5941 taaaggccac tattaactta ccaaactgag ttccatagtc acctaaatga tttattctta
     6001 tagtcttgta tccttgcgaa tcatatatct tatataaagc attacctata actgtggttc
     6061 ttatgtgccc tatatggaaa ggttttgcta tatttggaga agaatattca actattacag
     6121 ttttatcttt tccaaaatca ctatgtccgt aattttcttt ttcatctaaa acttttttaa
     6181 ttacagtttc tgctaattga gatttattta caaagaaatt tacatatccg cctaattgta
     6241 ttacttttgt tatctctcca cttggttcta tactttccgc caattcactt gctatcatgt
     6301 ttggagcttt tctaaacact ttggctaatt taaagcatgg aaaagcatag tcccccatat
     6361 ccttatttgg tggaacttct ataagtgcct ctatctcttc tttcgataaa tcttctattt
     6421 tttctttaag gcaatttgat attgccacct taaaatcttg cattctgttg ctcctctcta
     6481 cattgttcct ggtttatatt gtgcttatct ctttatgtta aatcaaattt cgtgtttttt
     6541 caagtatttc attacagtgt aaaacacttt aataattatg ttttctgtat atattaaaaa
     6601 tactataatt gcagttttta atcacactat tattgatttt ttataagact tttttctatt
     6661 ttattgtttc ttgtactatc cagttgactt tatatacttt ttttaatctt ttatcaattt
     6721 tcagacatca atattaattt tatatacatt tattttgctc ttttatctat ttttatacat
     6781 caatattagc tttatatact ttttttactc ttttatctat tttctataaa tctttttcac
     6841 tcttaacttt tattccttct tcttctaaca gccttgctgt tatacctttc cctggtatct
     6901 ttttacctga aaaactacca tcatatatta gattacatcc acaagagggg ctaccctctt
     6961 ttagtattgc ttcgctacat acatataaat ttgctatttt tagagtttca ttagcccctc
     7021 ttacaaagtt ttctgttaca tccttattat ctttagtaat tacttttcca tcaactatct
     7081 cagcaggtgg tcttggtgta gatagaccac ctaactgctc tgggcataca agtgtaaatt
     7141 ctttgccttt taaatattcc ttgacttttt cattttcatt attatcgcca ctatatttac
     7201 aatttattcc tattaaacat gcagatacca atatcataaa aatgtgctcc tatacaaatt
     7261 cttaatatat tcttatacaa attactaatg tattcttata caaattattt taatttaaca
     7321 attgttactc ctgctccacc ttctccatat tgaccacctc tttgtgattt tacatgtcta
     7381 tttcttctta aaatgtcttg tagccctgct tttaatactc ctgtacctat tccatgtatt
     7441 actgttacag actctaaacc tgccacatat gcatcatcaa gatacttttc tacttccatt
     7501 atagcttctt ctaggtttaa ccctctaagg tcaacttcat tttttacact accagatttt
     7561 gaccttataa tgtttctcgt tgatttagtt acatttgttg aaacatcttt gcgtgttttt
     7621 tgtaaagatt taaaaggtag agtcatcttc attataccaa tttgcactac tgcttctttt
     7681 ctctttttat ctactgaaac tacactacca ttttgattta aagttattac cttaacttct
     7741 tcacctggct ttaagtcttt tatctcctta tttgatacct ttggaactat catacttttt
     7801 actgttggct gaagacttcc catagagctg gtcaattctt ttctaagttc ttctatctta
     7861 cgattctttt cttttgaagc tctttcttgt tcaagatttc taagttcttt tattataata
     7921 tctacttctt ctttagcttg tcttataatt gaaaatgctt ctgatttagc tttttcaatc
     7981 atcttatctc tttgactgac caatttttca agtttttcgt catactctac tttcagtttt
     8041 tcaatctctt cttttaatct ttcagcttct tctctatctt ctactgcttt gattctattc
     8101 ttttcaacat tctgtaacac atcttctaaa gctatgtttt ctgtatttat atattcttta
     8161 gcacgtgaaa tcacataatc acttagccca agttttctag aaatctcaaa cgcatttgat
     8221 tttccgggaa cacctataag taacttatat gttgggctta aagtttctat atcaaattca
     8281 actgctgcat tttctacacc tggtttagta agagcataat ttttaagctc actatagtga
     8341 gtggtagcta tacatttagc tcctacagaa tttatatctt ctaatactgc tattgcaagg
     8401 gcagctcctt caacagggtc tgttcctgct cctaactcgt caaatataac taaagagtct
     8461 gctgttacgt tttgtaatat agatactata ttcgtcatat gagatgaaaa tgttgataga
     8521 ctctgttcaa tactctgttc atctcctata tctgcaaata cattatcata tacacacata
     8581 ctacttccat aatcagcagg tatatgaagt ccactttgtg tcataagtgc aaatagacct
     8641 acagttttta ttgtaacagt cttaccacct gtgtttggac ctgttatcac caatgtatgg
     8701 aagtctcttc ctaaataaat tgtatttgct actaccttct ttttgtccag cagtggatgt
     8761 cttccatttt ttatgtttaa atatttatcc tcatttaaag ttggttctat tcctctcatc
     8821 tgtatagaaa gttttccctt tgaaaatgca aagtccaatc ttccaagtat ctcttgatta
     8881 gagattaaat cttcgctcac ttttccaacc atagcagaaa gctctgataa aattctttct
     8941 atttcctctt gctctcctag tttcaactgc ctcaattcat tgttcatctc tactatagtc
     9001 attggctcta taaaaagtgt cgcaccagaa gatgactggt catgcactat accagctact
     9061 tgcgacctat attcagattt tacaggtact acaaatctat cacctcttag agaaattatt
     9121 gcatcttgta agtacttttg ataagtagtt gaacttatta ttgaatttaa ttttgaccta
     9181 atggattgat ttttttgggc tattcttctt ctgatatctc taagtgtact tgaagcattg
     9241 tcagatattt ctacttcact aattatagca ttgtatatct ggtcttctat gtccttgtat
     9301 acatatagag aatttgatag agattgtatt attggataat taaaatcttc ttcatcacta
     9361 ctagataagc tatttcttaa tcttctagct actcttaagg tatctgctat cataatcaga
     9421 cttcctgggt caagagaagc acctatataa gctctcttta ccttatcttc tatatcatga
     9481 ataccttcca accctactga acctctcttt ataataattg attgagcttc actagtttct
     9541 tctagcatag atttaacttc tacaaaatca gtatttggta ctaaattttc tatatatttt
     9601 agacctaaag aagatgaggc tttcttcttt aacaaatcta ttattttatt gtattctaga
     9661 actcttaacg atttctcatt cattttctat attcaccatc ctcgatattt taactttttt
     9721 atttaatttt aaaaatgtat gttttcaagc atttccaata aaaaatgcaa gttttatttc
     9781 tttttcattt ctaaaattat tatatttttt ctcttttaga tatattttac acatattttg
     9841 tattatacta tgtatgtagc tatctatata ttatacataa acatgcttta tttgtaatat
     9901 aatctgttaa aaaatcttct ttaatatttt taaaggagtt tattttagct tataaaaaaa
     9961 atagctactt atatagataa attaaggagg aacatgagtc atgggaaacg tattagaagg
    10021 attaaaacca gaaagtgttt ttaaaaactt tgagaaaata tctcaaattc ctagaggttc
    10081 tggaaatgaa aaaggcataa gtgatttttt acttagcttt ggtaaaaatt taggtcttga
    10141 aactattcag gatgaaagct taaacataat aataagaaag cctgctacaa aaggatatga
    10201 aaattgtcca ggtgtagttc ttcaaggaca tatggatatg gtttgcgaaa aagaaaagaa
    10261 tgttgaacat gattttctta aagaccctat aaaattaaga attgatggtg acatgatata
    10321 tgctactgga actactctag gagctgacaa tggtatagct gttgctatgg gtatggctat
    10381 attagaagat aatactttag agcatcctgc actagaagtt ttagttactg ttaatgaaga
    10441 agatggtatg aatggtgcag atgcactaga ccctagctta attaaaggtc aatatatcct
    10501 aaatatggac tccgaggagg aaggatactt attagttagc tgtgctggtg gtaaaacttg
    10561 tgttgttagt ttacctgttg aatacaaaaa agtggaaggt gacaaacaag gattattagt
    10621 tgaggttact ggactattag gtggacactc tggtatggaa attgttttac aaagagcaaa
    10681 tgctaacaaa gcaatagcta gagtattaag tgtattgaat gttgattatg aattagcttc
    10741 tgttgatggt ggtactaagc acaatgctat acctcgtgaa gctaaatgtg taatagctgt
    10801 taataaagct gatgttgaat ctgctaaaaa acaaataaat gacattttaa ctgcatttaa
    10861 acatgagttt actacttctg accctggcat gacttactca gtagctgaaa cttctgtaga
    10921 caaagttctt actaaagatt gtaaagaaaa agttgttcaa atgtcttgct taactcctca
    10981 tggagttcaa tcagtaagtc ttgatataga aggattagtt gaaagttcta ctaacttcgc
    11041 tataattgaa actaaagaat ctactattga atttttaact tctgttagaa gttctgttat
    11101 gtctattaga gatgaaatcg ctgatagaat aagacttttg gctcaagctt taggtgctaa
    11161 ttacgacctt atagctcaat acccagcttg ggaatttaaa aaaggctcaa aattagaaaa
    11221 aatatgcagt gaaacttatg agaaattaac tggtaaagtt cctactgtta tggctctaca
    11281 tgctggtctt gagtgtggat tattacttga taaacttccg catgctgaag ctatctctat
    11341 aggaccagat atgtttgatg ttcatactcc aaatgaacat gttagtatcc cttctgtagc
    11401 taatgtttgg gattatgtta ttgaaatatt aaaatctatg aaccaatatt aaatttaagt
    11461 tttgattcta aatagatttt aattttaagt aatctatata aaattaactc tgtaaattaa
    11521 tactactgtt agtataatat ttactttcaa tattaactta tagaaataaa gcctaatgat
    11581 agataataac atgtatcatt aggctttatt gtaatttaaa tattattaaa ctttattctg
    11641 ttttaaaatt aattcttata ctattttaaa tctatttctt ccttgtctct tagaatcata
    11701 aagagcatta tctgctattt gatacagttc atcatactct tgaccacgct ttgttataac
    11761 tacccccata ctaatagata aactttctcc atttggcaac ttaatgagat gaatatgatt
    11821 gtatacatca ttacatttat tgataagttc ttccttattt attatatcat ttatataaac
    11881 actaaattca tctccaccta aacgacctac tatatcatct tttgcaaaac tttcatcaag
    11941 tacctttgca acatcaatca gtactttatc tcctaccagg tgaccataag tatcattaat
    12001 tgacttaaaa taatcaatat ctataatcaa taaagctcca tttttttcag ttgataaatt
    12061 taataaattt tgtgtagtta attttctaat atatgctgca ttataaatat ttgttaaact
    12121 atccctttga actttatcca acaatctatt cttttcctct ttttcagaat caatattagc
    12181 tattttccca attacataca ttggtatttt tctatcatta taaattattt ttgaagtaat
    12241 tctaatccaa tgaaaagtat catcaagcat gatagaatac atttcagtag tcccattttc
    12301 ttgtgatttt attacatcaa aaaacttttt attatattct cttcttattt tatctctttc
    12361 attttctata ttgccatttt cactttcctt atcactttta tccaaaccat aataagtctc
    12421 aatacccttt tctggcatag aaattatcaa tttatcttgc ttataatcat actcaaaaaa
    12481 gtattcactt gtcatttcat acaactgagt atgttttttg agttccaaag atatcttttc
    12541 gttcatactt gtacgagtat gtaaaccaaa tgccataaat ccaataatac aaattaataa
    12601 acttgctaca ataaaaatag tctcaattgg attttgttgc ataatataaa gcaacgagaa
    12661 atcttgtcta tatgtagtat tttggtagac aattgattgc attttttctg atgaaatact
    12721 tataatagct ttattaaata tattcaataa ttcttgttta tcttttttaa ttatgccaaa
    12781 acaaatactc tttgcttcat aagtttgagg aactaggcgc acatttttat acttaggttg
    12841 attcatatag tactgcatag aataaccttc tccataagtg taatctgcat agcctttatt
    12901 aacagcttct atacactctt ctaaattatc ataccaaact atattttctt caaactgacc
    12961 ataataatca atacctttgg ctagagctat acgctttcca tttagactat tctcatttaa
    13021 tttattatta atcatcatag tatattgagt agaaagaaaa ggccgagaca tagctatatt
    13081 atgttcacga gagtactcat aatcataaat cattcctgct acaatatcaa tttcatgttt
    13141 tttagccata tcttccaaat cttcttgaga ttttacaggc acaagttcaa attccaaacc
    13201 tgttttatca catatatgat ttaacaaatc aattgatata cctcttaatt ctcctgtatc
    13261 tttatctgca ttttgaaacg gtggtttgtt taaaagtact cctactttta atttttctgt
    13321 atctttaatg taattagttt cttcatcaga taaaaacatt tgattattct ctggcgtaaa
    13381 gtatttctca tataaagtag ttgaaaaata tgggtccttc tgttcaatat tattaattgc
    13441 tgaattaagc ttttgagtta agtctgtact gccttttgga gtaatgaaat aaaatggctt
    13501 tgatgagaat tttgctacag tacgcacacc ttctattggg ttcatactaa cattaagaag
    13561 tacatctgct ttaccactct ttagtacttc taattgctcg tcacttgttt tacaatatac
    13621 caattcaggt gacataagat tcattttaca atactcatct aattctttaa gcctagtatc
    13681 agaattttct attacagcaa tacgaatttt tttcacatct tgcgaactca ttatgttatc
    13741 aatatctgta ttttcatata atgcttgtag tactgtattt gctactccat aactgtttcc
    13801 cgcataatta tatatttttt gcattggctc attgtataac atacctccca ttatatcaat
    13861 ttcaccattt tctaacatct tcattaattt tgtaatagat tcatttatct ctccaggaac
    13921 ttgaacaaat tcataattcc atccagtata ctgtgcaatt tctagcaaat attcatatgt
    13981 atacccaaaa tagttacctt gctcatctat ttcagttaaa cctttttgaa taggataagc
    14041 aacacgaatg gtacgattat cattacctat agcattgata ccaaaagaaa atatgcaaga
    14101 agtgaatata gatgtaatta caataattaa taaaagtaat ttttttaaat tcactacaca
    14161 atcctccata tagttaagat ttacagtata aattactgca taaacttgta gacatgaaaa
    14221 aatagattag tatataaaag gatatataaa tctacttaga aatttaaata tccttaatat
    14281 atacaatata tttaaattat aactcattta tatatctatt acaacaaatt taccctgcta
    14341 aatacctact ctatatccca taattttaca agttgtaatg aagtttaagt tctatctcat
    14401 ttcaaattta gcagtgtttc tatttacagt tcttttatat ttcacatctg gataacccaa
    14461 tataaatgaa gtgataactg cttcgttctc gctcattcct aacagttctt ttatctttgg
    14521 ctctacattt gatgccataa caaaaaatcc attataacaa attcctaatc cttgagaata
    14581 ggccataagt tccatattag atgcagccaa tcctccatct acataagcac ttccacctag
    14641 agacatatca cctacaacta tcataagtag tggggcatca taaaataaag aatcatttcc
    14701 gttctcttta tatcttttgt acattttctt aaatgtattt ttatagatag aacgtacagg
    14761 gtcattgtca tcagtatcta atgccaaatt ataaagacct tgtattgcca gttctttcac
    14821 ttcttttagc ttttctttta ctaatatgta tcttataggc tgtctattac cacctgttgg
    14881 tgtgtatcta ccagcttcca ctattttttt tattttttct tcttctacct ctatatcttt
    14941 atattgtctt atacttcttc taaatttaat aaaattcaat aacttttcgg gttctaattc
    15001 aaaactttca cgattgtatt ctattacttc atttttatca aatccttgca tttctattgc
    15061 atctgttggg caaattgcca tacagtgacc acagttaata cagagaatat ttttaacctt
    15121 tgctttatca tccttaactt ttattgcatt tacaagacag tctgattcac acatcccaca
    15181 gcctacacat ttttctaaat ttatgtctat cattccaaat tattcctcct tttaaaaaat
    15241 ttactttagt ataaaacaaa tagttgtcta agtcaatttt tattttttta acaatatact
    15301 aaccttaact acactttaat ggagaaaaat atacataaat tggaacttaa attagaactt
    15361 attcaaagta aaagataaaa gaagtagatg tctaaaagtg aactttttag ttaattagat
    15421 attctttatt gtatgaaatc aagtggatat ttatcatttc aacaataaaa aaggcttacc
    15481 tctattttgg atatgtcctt gttaagtaga cagactaaaa aaggctatct ttatgcactg
    15541 agatagcccc ttttcccaac tactattgtt tattttaata ttatatcaat aaatttaatt
    15601 tgctataacc tgtaagttac attttaattt gatgtaactt taaattacat ttttaagtaa
    15661 tatctttaaa ttatattctt aaaatatatc attaaactac attttaatta atctaaaaac
    15721 tatatcttaa ttaatctaag aaacttacat tataatcttt tagtttccca ttatcatata
    15781 caatctttgc actaaagata tttccagtct tagcccaatt taagaacaac ctgtcacctt
    15841 cccacatatt taaatcgaat attttatcat tatcaaccca aattaaattt ccttctttac
    15901 aatcatttaa atctttttca gacaattcac cttcaaactc atctgagaaa tacaaaaaca
    15961 tataccaatc ttcttcatct ttaaattttg gaaaagttat caacccttta tatgtcaatg
    16021 atttaagagt aagaccagtc tcttctttta cttccctaat tacacattct tctggagtct
    16081 ctccttgctc aaactttcct ccaactccta catacttacc ttcatgtata tcatctttct
    16141 ttttatttct gtacaacatc aaagtcttgt catctttttc tatataacaa atagttgtaa
    16201 gtttcatgta tctcgcctta ctttctcttt atattctcaa ttaattattt tcagcacttt
    16261 caagcacatc acttatattc ttcattgcat taagagaaag ttctgcaaat tcatcaaatg
    16321 gaatccctat atcttctata cttctcattg catctctatt tacatttgaa gcaaatctcg
    16381 tttctttcat tcttttaata acagacttag tctttacact agtaagtttt ttatctggat
    16441 aaactaaagc tatagcagtt ataaacccag ttatagggtc tgctgcatat attgcttttt
    16501 ccattaagct agttcttgta actcccattc catcatgatg accaagtatt gctctataca
    16561 tttcttcgtc accgaagttt tcttttttaa gcagttctac tgttgttgta gcatgtcctt
    16621 cacatatttc tcctggcttt cttccaacta tatctgaatc caaatcatgt aaaagacctg
    16681 ccactgccca ctcttcttct ttttctggct ctagtctttt ggctaattct ctcataacag
    16741 cttcaacagc ataacaatgt tttctcattc tatcagtttc taaatactta aataaaattt
    16801 ctaaagcttc ttctctcatt ttcaccaatc cccctgtttt ttcacatata tgatattttt
    16861 atatattaat acacataaat tcaagtcttt atatatattc atgtatattt ttcatgttat
    16921 atctattcta cacctttata gtagtgtcct gcaactgttc caatttcatc taatttctta
    16981 tacaagtctg tagccttttt tccaagttta taattattac tcaatacctc aatgtgagct
    17041 tcaataacct ttttaaccat ctcactatct tcaactgtaa aatctatcct aaatacatct
    17101 attccaattt cctctaactc atatagattg tccaacatac aagtaacctt cgaattgtaa
    17161 attgtacttc tacagaatat atcttgtgtt atcctataac ttgcatccgt aaagtctctt
    17221 aaagcataac tactttcctt acatttagca actctcttgt cctttttaca atccctaaca
    17281 actactccca taggacagta ttctgtaacc atcataggag catatccata tattactgct
    17341 tcaatttcta catctgtata ttttaaagtt tgtttaattt catttaagtt tagttcttgt
    17401 gacaaacaaa ctgtacttgc tccctcttct ttgaagtggt ttatactttc actattgaat
    17461 gcatttaagt agcaatctat atttaagtct tttttcttaa agtattccat agagccccag
    17521 ttaccaattt gaaccttatt aattcctttt atattatcca atatctcaaa ttgcttgtac
    17581 tctttatttc taataatcct tggtgctgaa tagattaatt ttttgtcagt gactactata
    17641 ttagagtggt tcttattcaa agtatctatt ttacttgtat ttgacaaagt atctatgtta
    17701 tttgtatttg aacccattag ttctttagga atacctaaag acgaataagt atctaaatcc
    17761 atagaaatac ttgaatctat agaaatactt gagaccattt gtaaagcttt tgataatgta
    17821 tttatatctt cataatagat taaatccaca ttataattta atactgcttc taattgctcc
    17881 aagttcttaa ctttaactct aatcttagga actgtatcaa gttttttctg tttatttact
    17941 ctatttggct ggtattttaa tctattcttc ttaaattttc taccttttat ctttattctt
    18001 tcttcatcta aaagctcaat acaatccctt ctcatttgat ttaacacact tataggcata
    18061 cttacacctt catccaggtc aatttctatc tcttttaact tatatggtgt atttccaagc
    18121 ttttgaattt gtgtttctat tttttcttta cttaaagcca cctttatagc tttttcaact
    18181 attttttctc cttctaccac cgatttattt ccacaaaaat cacttataaa aagctctggc
    18241 tttttaccta gtttaatact cacttttgca cgtatattag tttttattaa ctctttatct
    18301 tgttggaatg tagcttgtac tctatccatt aactcactat ctgaagtctt aaatataagc
    18361 tgatttctct ttgcttcgcc aacaaaatct aattctatca aatcgccttt atgtgctatt
    18421 gtagttatct ctccatcttt tattatcctt ccaatagtac ctccacctag attgattcca
    18481 tcaccttttt taagtgtgtt ttctaatatg actctaagcc ttttgcttct tctattgtaa
    18541 tctaaaactt ttccaacata tagaccttga ttattaggtc tattagagtt cattacatcc
    18601 ttaccaactt cacctagtat atatcctttt gtaaactttc tattaaatat agtatacaaa
    18661 ttatttatta tttcatcaga aatacttatt ttattcttat ctacaaattc attaattgct
    18721 tctctatatc ctgaaactac agtagctaca tattcaggct ttttcattct tccttctatt
    18781 tttagagata atacacctgc ctcaattatt ttatctaatt cctctatagt acttaaatct
    18841 ctaggactca acaaataatc tccatcactc tttactactt cacctgtatt tatatctatc
    18901 aactcatatt tttgtctaca tggttgtgca cacctacctc tatttccaga cctattgcct
    18961 atcatactac tcatcagaca ttgacccgag taacatacac ataaagctcc atgtacaaaa
    19021 acttctatat ctacagttgt attttcacaa atccatttta tctcatcaac atttaattct
    19081 cttgctaaaa caactctatc aaaccctaca ctctgaaggt attttacatc ttctaaggaa
    19141 tgtgctacca tttgagtgct tgcatgtagt tcaaagtcag gtaatagttt ttttataagt
    19201 cttgccattc ctatatcttg tactattaaa gcatcaatat ctatatcata taaaaatttt
    19261 acatattcta caaaatcctc tatttcatac tgttttatca gtgtattcac tgtgacaaaa
    19321 acttgcactc cccttatatg agagtattta acagcatcaa ttagctcatt tctatcaaag
    19381 ttgtttgcag atgctcttgc actaaagtct ttaccaccta agtacacagc atttgctcca
    19441 ttttgtactg ctgcttttaa tgaatcaaaa gagccaactg gtgcaagtaa ttctattttt
    19501 ttcatatttt tctcctctat ttatacttat tagattaata taattatcta taacacacac
    19561 acttacatta aatttataca ctacttacta tatctaaatt gatatactat ttaccatata
    19621 cagtatatca aataataact ctttttttat caatttacac taagttagtt ttcgttaaat
    19681 gaatcatcct tattgataaa cataactcca aagactactg ccaaaataaa gaaacatact
    19741 aggattgact tttccacaaa aatctttgta aaaaaagttc ctaaaatagc cccagatata
    19801 aagaatacaa taattgcata atactgcaaa ctctttttta tcataaaaat attcttagtc
    19861 tgtatataat gaaataatgt ttctgtagca cttcttaaat ttccagtaca cattgtagtt
    19921 gcaaaactgt ttccatttac ttttctaaaa ctctctacct gcattgaaca aataaaagat
    19981 atagcaacat ttacaaacat attaaattgt cctctaggta caaaagaaac tacaagtatt
    20041 gtaatcattt caattataat aataacttga cgccaatgaa tcttagaatt atctttaaag
    20101 tactttctta tcttctctgc tataaataca cctaacataa atgccaaaat aggaatcaag
    20161 taataaaaag atttttttat attcccttct gctatattaa gccctaataa aactatgttt
    20221 ccagtctgtg cattggcgaa gacctttcct cttactacat aagtataaat atctaaaaat
    20281 cctcctgtta ttgccaataa agaacataag aagaatgatt cagacatctg gctctggctt
    20341 gtcatatata aaacatctca ctttctaatg atagatacca aatcaaaatt attttagata
    20401 ctatttttta ttaatattaa aaaaactttt atctgtataa atatttgtat ttatacatta
    20461 aaagaagctg tctcaacaaa caatagagac agcaaatctt ttaattttat ttcacatttt
    20521 tttcatcatt atttaaccct gtacatttta gctgtaaatc ataagctttg ttttgaaact
    20581 cagaagctaa attctcagct attgtagctc tctcatttgc ctcttcaagt tgagcactta
    20641 gttcctcaat cttgctttta taagcatcta actcggctct agaaccttct gtcgtattac
    20701 taagttcgaa tatttcttgc tttttatttt ctataatatc aattaactct ttcatcttag
    20761 cctcagtttc acggctttct gcttcttttt ctgctattgt aagctttaga gacttgattt
    20821 ctaattgaag ttcttcatta gatgccccaa cttttttact caattcttca ttagctttaa
    20881 tcaacttttc attctcatct gaacattcaa ataaaaggtc tgatatattt aatgcagtta
    20941 gtatcgcagc aactgataag ctcaatttcg ggttttggcg tgttatttta tccatttctt
    21001 tgtctacaaa atcagcaata ctaatcataa acttctctga tttgtctcca accattggat
    21061 attcagcgcc atggatttta accattactt tgttcatcct aacctccccc gacattagtt
    21121 gttaatttga tcttaagtta gcatttaatt tttcgcttaa ttcacttaat atcttatcat
    21181 gcaccttagc tacatcttca tctgttagag ttttatcttt acttctataa gttattgaat
    21241 atgcaattga cttgtatcca gcttctattt gagaaccttt gtaaacatca aataacttgt
    21301 agctttctac taatccttga ccattttcct ttattatatc ttctatttgt tttacaaata
    21361 catcatcttt aacaataaga gctatatctc ttgatgtaga tggatatttt ggtaatggca
    21421 cataattctt tgttctatca gaattatcaa atacaaagtc aatatctatt tcagcgacat
    21481 aaactctttg acctagattg tagttttcta taacatctgg atgcaattca cctaatgtac
    21541 ctacatattt attattatac actattttag cacatctacc agggtggaag gtagtattat
    21601 tatcttgagg ttcaatttca taacctttaa atccgacatt tacaagtata gtttctatag
    21661 ttccttttag tgcaaagaag tcaacatctt taccatacat acctacacac attctatttt
    21721 cttctttagg taattctgaa tcttgtggga tgaatatatg tccacactca aatgcagata
    21781 cttcttctat tttatgagat acattagttg ataaaacatc taacatattt ggtattaaag
    21841 tagttctcat tacagaagtt tcttctccta atgggttaag taatttaaca aagtttctct
    21901 tagcattacc ttctggtact cttatcttat cgactccctt agggcttaca aatgaatatg
    21961 ttaatatttc atttaatcct acagcagttg aattatcttt taaagcatcc atgaattttt
    22021 gttttgaagt tttaattcct gctgtcgtat ttccttctaa ttgtacagaa ggtatattct
    22081 caaatccata aattctagct atttcttccc atacatcagc ttcttgttcc atatctgttc
    22141 taaagcttgg tacatctatt tctaatttat cattagctac caaattacat ttaaactcta
    22201 atgattctaa aattcctaca aactgctcca ttggtacatc tacacctaat aggtggttaa
    22261 ttctttgagg atttactacc aattttttag gttctggttt atttggatat acatctacaa
    22321 caccttttaa aacttttcct gctcctaaca tttcaacaag ttgtgcagct ctatttgctg
    22381 ctatctctgc aagattaggg tctaagtctt tttcatttct tgaagatgct tctgacctaa
    22441 taccaacttt tttagctgtc attcttatgt tttctggttt gaaattggca ctttcaaaaa
    22501 gtacagtctt cgtattagaa gttatttctg agttagcacc acccattaca ccagctaaac
    22561 caagtgattt ttctccattt gttataacta gcatatcttt atctaatgtt ctctcaacat
    22621 catctaatgt tacaagtttc tctccatctt tagcatttct tactactatt cttccagtct
    22681 ctacttgatt tatatcaaaa gcatgaagtg gttgaccaag ctctaacatt acgaagtttg
    22741 ttatatcgac tatgttactt ataggtctta ctcctgcttc tgtaagtctt ctttgcatcc
    22801 aatatggaga aggttctatt tttacatctg taaccattct agcaacatat cttctacata
    22861 aatctggatt atctatctca actttgaaat ctatctcttc gtcactttct tttactttga
    22921 tttcaggata ttttactttt gttcctatag ttgcagctgc ttctctagct atacccatca
    22981 tgcatttaca atcaggtctg tttgaagtta attcaaaatc tattaaagca tcttttaatc
    23041 ctaaaacatc ttttatatct tttcctaatt cataagaatc ttcgtggtct aaaatatata
    23101 taccacctct tttatactcc tcaatgtaat gttcatctat acctagttca gctgctgaac
    23161 acatcatacc atctgataat tcacctctga aatcagtctg tttgatttca actcctccag
    23221 gtaacttaga accatttata gctactggaa tataatctcc ttctgatata tttgtagctc
    23281 ctgtaactat ttgaacaact ttatctccaa tatctacttt agttacaacc aacttatcag
    23341 catttggatg ttgttttatt tctaaaatct ttccaaccaa tatattttct atttcttcac
    23401 cataataatc tattgtttca actttagttc ctgtcattgt cattttatca gcgaactctt
    23461 ttacatccat gtctatatca acatagtctc taagccattt taaagatact aacatctaca
    23521 taccctccta attaaaattg atttaagaat ctcatatcat tttcgaataa taatctaata
    23581 tcatctattt cgtatttaag cattgcaagt ctttcaaccc caactccaaa tgcaaatcca
    23641 ctgtaaactt ctgggtctat tccacaattt ctaagcacat ttggatgaac catacctgaa
    23701 cctaatattt ctatccaacc ttcatattta cacattgggc aacctttacc accacatttg
    23761 aaacaagtaa catcaacctc tgcacttggt tctgtaaatg ggaagttgtg aggtctaaac
    23821 ttagttttga tatcagaacc aaacaatttt tcaacgaaga tatccatagt tcctttaaat
    23881 tctgccatag taacatcttt tccaacaaca agcccttcta tctgatggaa cattggtgag
    23941 tgtgtagcat ctggcgagtc tgacctaaaa catctacctg gtgcaattac ttttattggt
    24001 aactcttgac ttctcatagt tcttacttga actggagatg tttgagttct aagtaatacc
    24061 ccatcattga tatagaatgt atcgctcata tctcttgatg gatggtcttt aggagcgttt
    24121 aatgcgtcaa agttgttttc aacagtctca acttctggcc cttctgctat agagaatccc
    24181 attccgataa atatatctgt tacttcatct ataatttgag ttattggatg cttcttccca
    24241 acctttaaaa cttttcctgg ttgagtaaca tctatcactt cctcttttaa ttttctttct
    24301 ttttcaatag catttatttc ttctttttta gaatttatgc taagttcaat gttttctctt
    24361 acctcattgg caaccttacc aactactggt ctttcttcag cagataattt acccatttct
    24421 ttaagtatgg cagttatctc accttttttt cctaagtact taactcttaa actttctaca
    24481 ctttctatgc tttgtgcttc ttttatttca gccaaagctg cttcacgtaa agcaagtaat
    24541 ttttcttgca cacatatcac cctttcgttt ttttgtataa aaaaagcccc tcaatccctg
    24601 tctagggacg aaaggctata gtttcgcggt accaccctag tagtttaaca atttaaaaat
    24661 catcaaacca cctctaacaa acttaacgcg tttttgacgt caaagcctac tgtaaaattt
    24721 cagctctgtt actccagagg gaacttctca tgacctctta gaaaacactc ccagcctagg
    24781 tgtttatctc tttactaagt ttaatcaaaa tactttcctc tttcattgca tttacaatat
    24841 tatattgttt attttagtat tatatcattt ccattcaaat tatgtgacta tttttaatat
    24901 atatccaata c
//
LOCUS       DACTZW010000064        24787 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.064, whole genome shotgun sequence.
ACCESSION   DACTZW010000064 DACTZW010000000
VERSION     DACTZW010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24787
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.064"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            <1..689
                     /gene="vanR"
                     /locus_tag="JAM15_13175"
     CDS             <1..689
                     /gene="vanR"
                     /locus_tag="JAM15_13175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="VanR-ABDEGLN family DNA-binding response
                     regulator"
                     /protein_id="HAT6799206.1"
                     /translation="ILVVDDERDIADLIEVYLTNENYIVYKFYSGLDALNCINLNEFD
                     LAILDVMLPGVNGFSLCQKIREKYTYPIIMLTAKDEETDKITGLTLGADDYVTKPFRP
                     LELVARVKAQIRRYKKYSGSLQSGEELSHIFSFLGLELNTQTYECHLNGKALSLTPTE
                     FSILHVLLKNKGSVVNSENLFHAIWKDEYYNKSNNTITVHIRHLREKLGDTVDEAKYI
                     KTIWGVGYKI"
     gene            725..1840
                     /locus_tag="JAM15_13180"
     CDS             725..1840
                     /locus_tag="JAM15_13180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAT6799207.1"
                     /translation="MKKINNFTYRKLRDKYKFIKREKNTEAYLKYKLYIMLAIYTGIV
                     LVLMFMADYTFSNFSNPLVKWLKLRRDVLFFLVFIIGYITIFNFYWKKPWNYLREIIN
                     ATHTIYQQNDELVELSKPLKEIEQQMNQIKMSVLLSQQAVKEAENKKNNLVMYLAHDI
                     RTPLTSVIGYLSLLKEIPNMDNSQKSKYTEVALDKAQYLEKLINELFEITRYNSNQIK
                     INFEKVDLYYMLLQLKDEFYPLLSEKGNRAILKANESLTIKADSEKLARVFNNILKNA
                     IAYSYPNTEIIISAVHKDSKVDIAFRNYGQTIPEEQLSAIFEKFNRLDEARKSDMGGA
                     GLGLSIAKEIINLHGGDITVQSKDEVTTFTISLPTST"
     gene            1985..2872
                     /locus_tag="JAM15_13185"
     CDS             1985..2872
                     /locus_tag="JAM15_13185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6799208.1"
                     /translation="MELKIEHVTKKFKDKIAVEDVCLTLTPGVWGFLGANGAGKTTLM
                     RIITDIMKPTNGKILYNGKNIYIMGAEYRNLLGFLPQEFGFPQDFSVKDYLEYIAALK
                     DVPPREVKGKINNLLEILTLSDVKNKKIIKLSGGMKRRVGIAQAMLNDPKILIMDEPT
                     AGLDPGERVRFRNFISEFSHNRVVLISTHIVSDIEYISTQNAIMKSGKILDVGTTDKL
                     VKKVEGKVWECLISNRDISKYEMNLRIINQRSEKNNQVSIRYLAEKSQIDNSIAVEPR
                     LEDLYLWLFPEAVYSKEGK"
     gene            2873..4108
                     /locus_tag="JAM15_13190"
     CDS             2873..4108
                     /locus_tag="JAM15_13190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6799209.1"
                     /translation="MRIFYLEIKRVLHSRRTLILLLLALVLSALMAFLPITYEGINYL
                     DDNGKVVELSGLDAIKYKKTIYANNSEISSGVVTPKKLKHALNIWKKTEEKYGKVGSE
                     DFPLDIYSKSILPIRPLLNRLPEAFANSETGFATELSEINTNDLDSFYEQCKTHLNDI
                     MKIERQTSSAQMKAQELYRKVDTPFEIYPGYSKDAFDYIIFYIFILLIICVAITAPTF
                     SGEYQTQSDSILRCTKHGHTRLAFTKILVLFSIFIVMFVVCISIHLAISDLAFGTECL
                     KTSFQMLFSVISLVNINLLQAQILIAIGGLISILAMVSLTLFLSAKCKDSLTSMLIAF
                     SICLIPMGIGVSWIGYLLPPGGIGLKISLLYQMTSFNFLHLGGMSFWTPHIILFFSVI
                     EIPIFIFLAIRTYCKHQVS"
     gene            4490..5407
                     /gene="pstC"
                     /locus_tag="JAM15_13195"
     CDS             4490..5407
                     /gene="pstC"
                     /locus_tag="JAM15_13195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HAT6799210.1"
                     /translation="MIVKSRLVGLEKNDNNGNKTKYVIEKVAKNIFLLSALVAVASLL
                     LIIGFVFYKGLRPFIFEGYSFIDFLTGADWVPSANKFGISSMIVASIFATLGALVIGV
                     PVGILTSVFIAEVAPKRLAKIMSPAVELLAGIPSVLYGVFGLAVIVPTIQSIFNLPKG
                     QSLLAIVIVLAVMMLPTIISVSETAIRAVPKAYKEGSLALGASKIETIFKVVLPAAKS
                     GVLAAVVLGVGRALGETMAVILVAGNSPVMPTAITDSVRPLTTNIALEMGYAFGTHQE
                     MLFATGVVLFTFILILNLVLNKLSNKAVN"
     gene            5409..6233
                     /gene="pstA"
                     /locus_tag="JAM15_13200"
     CDS             5409..6233
                     /gene="pstA"
                     /locus_tag="JAM15_13200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003460575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HAT6799211.1"
                     /translation="MRKFKENLLKSLVYLSALFTIVSLVIIVGFIFIKGIGNMNFNFL
                     FSNYSASGDGGILPMIITTLYTVVVSIVVATPIGILAAIYLQEYAKKGKAVTAIRFAT
                     ESLSGIPSIVYGLFGGIFFVVTLKMGYSIVAGSLTVAIIILPVIIRTTEEALKTVPQA
                     YRESSLALGATKFQTLYKVVLPSAIPGILSGVILSVGRIIGESAAILLTAGTVAKMPG
                     GIFDSARTLTVHSYLLTKESGDIATAASIGIVLIVIVLALNMLARFVAKKLNKANY"
     gene            6252..7016
                     /gene="pstB"
                     /locus_tag="JAM15_13205"
     CDS             6252..7016
                     /gene="pstB"
                     /locus_tag="JAM15_13205"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HAT6799212.1"
                     /translation="MELIDKIKMSVKDLDLFYGDKQALKKINMDIKENKVTALIGPSG
                     CGKSTFIRTLNRMNDLIEDVTIKGNISVDGEDIYTSDDVINLRTKVGMVFQKPNPFPM
                     SIYDNVAYGPRTHGLRDKKQLDKIVEESLKGAAIWDEVKDRLKSSALGLSGGQQQRIC
                     IARAIAMRPEVILMDEPTSALDPISTLKVEELIEDLKKDYTIVIVTHNMQQAARISDE
                     TAFFLNGEVIEFSDTKTMFTTPVDKRTEDYITGRFG"
     gene            7044..7697
                     /gene="phoU"
                     /locus_tag="JAM15_13210"
     CDS             7044..7697
                     /gene="phoU"
                     /locus_tag="JAM15_13210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HAT6799213.1"
                     /translation="MVNNSLDISIDTLKEQTVLMMEKCEEAIEKSVTCMIEKDLEGAR
                     KVVEDDEEINKLREEIRDKSIELIVLKQPMARDLRFIYSLGNISIELERIGDYAANIA
                     REMLKIGGEAYIKELIDIPKMAKECKSMMSQTREALILFDASIAYDVGTKDDIVDGLY
                     EQVQIDCLKIMHENSNTIDQGVKLLLIGRYLERIGDHITNVCEKIIFAIEGKMVEIG"
     gene            7855..8724
                     /locus_tag="JAM15_13215"
     CDS             7855..8724
                     /locus_tag="JAM15_13215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799214.1"
                     /translation="MKLQKMGMRTIKTGISVTLCMILGDYLVENMFYSLVACIISVQD
                     TVKGSLKTGINRVEGTILGGIIGFIFAIIKAGDPFLCGLGVMCSIYLCNLFKIKSVVV
                     ACVTFLAIHLGVGNSDPVYYSLHRVLDTSVGVLFGVLVNYYVARPNYLNSVIDEFKKI
                     EELSMLLIEDKILRKENLNVEKFEEEVEKLEEIYSKLIDELDYSLSETNIEKIENALR
                     ICREIHFHMQSIELLENKLYLKEHTYKYLKKTYNVDKLDWNIDEEKSPVFNYHLMKIM
                     IEIELLRKLNKSY"
     gene            8811..10247
                     /locus_tag="JAM15_13220"
     CDS             8811..10247
                     /locus_tag="JAM15_13220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase"
                     /protein_id="HAT6799215.1"
                     /translation="MNTRNDNSKILEIYKMKLFGELVKAVWNDDIEDIENLPNKILNE
                     DLKDNLNNYFSGKFDKDTMVNLIRVTMGLDVTEDTDKNLKESLHEAVNLDEVKRPIIS
                     VISDACKYCDENNKEDESCKIRSKHINCNEEDVCSACGDCVSRCKLGAISDKIEFIPM
                     IKLLKDIKSPVYAIVAPAFVGQFGKDVSPGKLRTALKKIGFEDMIEVALAADMLTAKE
                     AYDYYEHMKKDEEGCFITSCCCPIWVSLIQNSFPQILENVSPSVSPMIACGRAVKILN
                     PDAKVVFIGPCMAKKKEAMLEDIKDAVDFVLTFKELQEIFDALELNPAIMDESNRVEA
                     SLSGRVYARTGGVSKAVKLSVRRIDKNIKFEEKAFEGTKECMDGLKKVLNKEIEATFI
                     EGMGCVGGCVGGPKRILSVEEGTKNVDEYSESTNMETPFDNLNVLQFLTSLGIKRVES
                     LGEKEEEKVKKIFSRDIKSNKKENKYKK"
     gene            10295..11122
                     /locus_tag="JAM15_13225"
     CDS             10295..11122
                     /locus_tag="JAM15_13225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HAT6799216.1"
                     /translation="MKIKDNKAVFHVFIRIFLIAVLILTGTLLEEKINNVPVENISSK
                     GENTLELLSQSNTLGEIIYKASQEETKGPGATSEKVAYITIDDGPSKYTNALLDILKE
                     NDVKATFFMLNQNMKNHKEEVRRVLEEENSIGFHSVSHDIHKLYKSPEVTVGEFNTCN
                     NTLQEITGQSSKLIRLPYGSKPYMPEGSYNKLMANDYLIWDWNLDTQDWKSSTSQIVS
                     NILYYGRKRDELVVLIHEKEQSLNALNNIIRILKERGYTILPITENITPKNFWQENL"
     misc_binding    11423..11685
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            11761..14427
                     /locus_tag="JAM15_13230"
     CDS             11761..14427
                     /locus_tag="JAM15_13230"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HAT6799217.1"
                     /translation="MENTNLSKTYNPKDFEARLYKKWMDEGYFKSKPNPDKKPFTIMM
                     PPPNITGQLHMGHALDHTLQDILIRWKRMDGYEAFWLPGTDHASIATEVKVVERIKKQ
                     EGKTKYEIGREEFLKRAWEWKDEFGGKISNQLKQLGDSCDWDKERFTMDEGCNEAVIE
                     FFVSLYEKGHIYRGNRIINWCPDCKTTLSDAEVEHEEHDGNFYHIKYPLKDSEDFLEI
                     ATTRPETMIGDTGIAVNPEDDRYKHLIGKTAILPLVGRELPIVADSYVDLEFGTGAVK
                     MTPAHDPNDFEVGLRHNLEQLNTMNEDGTMNEVCGKYEGMDRFECRKAIVADLKEQGY
                     LIKIKAHNHNVGTCYRCHTVVEPRLSEQWFVKMEELAKPAIDILKKGELEFVPDKFDK
                     TYLQWLENIRDWCISRQLWWGHQIPAYYCQECGEIVVARKMPDKCPKCGSTHFKQDED
                     ALDTWFSSALWPFSTLGWPNKTEALDYYYPTSVLVTGYDIIFFWVVRMAFAGMFCMNE
                     KPFDHVLVHGLVRDSQGRKMSKSLGNGIDPLEIIEQYGADALRFTLTTGNSPGNDMRF
                     YMERVEFARNFANKLWNASRFVFMNIDEDIIKNMTRESVKEDLTLADKWIISRANNIV
                     KEATNNMDKFDLGIALQKIYDFTWSEYCDWYIEMVKPRLYGEDANAKSAALYTLTYVL
                     EKILKLLHPYMPFITEEIYTHLPTVEGCIIVSEWPKYNEEDNMAEEEDMMNLLMEGIR
                     SIRNVRAEMNVPPSKKAKLIIIPSEEKIEAIELGKDYFITLASASNVEIAKDKSNVPE
                     DAVGVVIDGVEIFIPLNELVDFEKEIERLSKEKKKLEGEIKRVNGKLANQGFLAKAPE
                     SLIEEEKVKKEKFEEMIKSVEERLTNLESKIK"
     gene            14852..15562
                     /gene="rgaR"
                     /locus_tag="JAM15_13235"
     CDS             14852..15562
                     /gene="rgaR"
                     /locus_tag="JAM15_13235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgaR"
                     /protein_id="HAT6799218.1"
                     /translation="MFRVVICDDEKIQRSILKEFTEKLLSERCLNYQILEFSCGEDLI
                     SKYPEKIDIIFLDIQMKDINGIEVAKKIRKFDEKVEIIFTTAFSEYAPQGYEVRAYRY
                     LVKPIEYSNFAMGVNLCIDNLQRKKERYIVLNSKKGFNRILIDSILYVETVKRDLVVH
                     TIGRDYKANMSMKQAEKLLCENGFFRCHTSFIVNLRRIEDLRDNMITINEQFIPISKY
                     RLKDLKVALTSLLCDIMY"
     gene            16626..17639
                     /locus_tag="JAM15_13240"
     CDS             16626..17639
                     /locus_tag="JAM15_13240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HAT6799219.1"
                     /translation="MNNKVKVAVLDTGIDKEHDYLKDNLVGGIAFECMHDYIFISDKF
                     DDEDGHGTACASIIKKEYEDVELFVIKILRKDGITNIKVLEEALRYLLDTNIRLINLS
                     LSVIGVESVKGLFEVCYELFRKGKIIVCSLANDFDLSYPAMFNNVIGVRGFTLDGDDS
                     FWYNKKYDVQCVMDSNSYISCDINNSYRLPPKCNSYLSAKLTGKIAKILSEKPGITIS
                     DLNDKLESLATRNHWDSCDFDECSRIVNFKLDLYDKENALLMKVADVVRDCLDIEDNN
                     EKLFKGSLFNKEIGLVYDNCFNLLKKLEHRFDIKFNYMDISKYDLVSIYTLTELVERY
                     KNL"
     gene            17772..19070
                     /locus_tag="JAM15_13245"
     CDS             17772..19070
                     /locus_tag="JAM15_13245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HAT6799220.1"
                     /translation="MKYEEALEYISQTNKFGIRLGLENIGKLLELLGNPQETLNIIHV
                     AGTNGKGSVCSFVSNILRECGYKVGLYTSPYLETFTERIRVNGQNIPQNDVARIIELI
                     KEKIEIMVKEGYAYPTEFEVVTAMAFYYYSEQKVDFVALEVGLGGRYDATNIITKSLV
                     SVIVSISLDHTGILGDTIEKIAYEKAGIIKENGVVLVYDQTDEAKDVIKSVCKEKKAK
                     YIEVDFDDINIKKSDINSQIYDCTVMKETYRDLEIKLIGEHQINNSILAISVIKYLKD
                     INKLANINEESIRKGLINTKWPGRIEKIKENPIFIIDGAHNEDGAKSLAKALDKNFKG
                     RKLTLLIGMLEDKDIDSVLEILLPHFNKVITTTPNNPRAINSDILREKVLKYVDDVTS
                     KHEIEDAVNYTLETSSEDDIIISAGSLYMIGTVRTLVKKL"
     gene            complement(19184..19429)
                     /locus_tag="JAM15_13250"
     CDS             complement(19184..19429)
                     /locus_tag="JAM15_13250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HAT6799221.1"
                     /translation="MKVTFNPSGVCCREMIFEVDENNVIVDAEFIGGCNGNLSGLRSL
                     IIGQNALEVADKLNGIDCGGKGTSCPDQLSKAIRQSI"
     gene            19577..20443
                     /locus_tag="JAM15_13255"
     CDS             19577..20443
                     /locus_tag="JAM15_13255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncE family protein"
                     /protein_id="HAT6799222.1"
                     /translation="MKIYISNYLSKSISIVDYSTLELEKEIVLEDNIYPHHFCIEKEK
                     NLIYIPSSSNGILYVLDLSNDKIIDTVSIGGSLSQVVLSDNELFVANEDSNSIYVLDK
                     NTLNPIGIIGVDNMPHGFDFDRESKKLYVPCINSIVCIDTINKNIQKKINMDFRAWHI
                     ELDKQKKEMYISTLDGKLIIIDEVSMDIKKVLYEFLLPVEIRFNYSGKKVYVADLGYN
                     NVRILDYTTSRYIGNIEINGIPQGLEISKDEKLLFVSDTQENSVKVYETANNKLIKEI
                     KVGKEPTTIICL"
     gene            complement(20447..20983)
                     /locus_tag="JAM15_13260"
     CDS             complement(20447..20983)
                     /locus_tag="JAM15_13260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4364 family protein"
                     /protein_id="HAT6799223.1"
                     /translation="MFENSSEELAYHKLLILYILEKIKMDLTNSQITQVVLETEMMNY
                     FSLQQLLSQLMESKFLTTYKDSDREYYALTQRGVESLEYFFNRIPTSVTEKIDKYIDS
                     NKENLLADTQVKSSFVKQSDNEFIVNLRVIENQSNLIDLNLNVSSEKQAKLICNNWKN
                     NASYMYAEVIDLLIRDIH"
     gene            complement(21173..21376)
                     /locus_tag="JAM15_13265"
     CDS             complement(21173..21376)
                     /locus_tag="JAM15_13265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HAT6799224.1"
                     /translation="MSNSNRTVVPEAKAALNQMKLEIANEIGLSNYENIDKGNLTARE
                     NGYVGGYMTKKLVEMAERQMAGK"
     gene            21667..22431
                     /locus_tag="JAM15_13270"
     CDS             21667..22431
                     /locus_tag="JAM15_13270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HAT6799225.1"
                     /translation="MKREVKRTKALIYSVLFFSLLLVLIFVFVYGIKYICSKSDNSKM
                     PIYKVDTNEKKIALSFDVAWGTDNMDDILKILDKHNVKATFFLVGSWVDDNEEIVKAI
                     DEKGHEIGNHSNTHANLKEISKEDITKEIETTSEKIYNITGKKTNLFRPPFGDVNNKA
                     MDICSDLGYKVIKWDVDSIDWKELGPNHVIEKVIKESQPGSIVLFHANINDVDNYLDT
                     IISRLKKDGYSLVKISDLLYKDNYVVDSNGVQKTKN"
     gene            22819..24132
                     /gene="prdC"
                     /locus_tag="JAM15_13275"
     CDS             22819..24132
                     /gene="prdC"
                     /locus_tag="JAM15_13275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase-associated electron transfer
                     protein PrdC"
                     /protein_id="HAT6799226.1"
                     /translation="MNKLYSILLKQHVGGPDKPVVSVGDVVKKGTLIAEPTGLGANIY
                     ASVSGKISEINDQAIVIEADEVQEDTFEPLKGEGILDLIKEAGVVGMGGAGFPTHVKL
                     NIDLNGGTILANAAECEPLLAHNIKEIEERPEIVYQGIKYAMEVTNAGKGMLAIKSKH
                     PKAIEAFKKVIKPGDNIEVAELVDMYPMGEERAIVRDVLGKLLEPTQLPSEANAVVIN
                     VETLTRIVEAVEQKRPVISKNITVVGQLNSGKESIVFEDVPIGTTVGELIERAGGIKG
                     EYGEIILGGPFTGKATTLDAPITKTSGGIIVTMPFVNEKRKMGLLVCACGPNEERMRD
                     IATKMGVTDIVSVQKCKQAQEIKGALKCENPGHCPGQAQKCIEFKKAGAEVILIGNCT
                     DCSNTVMGSAPKLKLGVYHITDHVMRTVNHPLIRRIKGDVRLKIK"
BASE COUNT         9806 a         2627 c         4325 g         8029 t
ORIGIN      
        1 aaattttagt tgtagatgac gaacgtgata tagctgattt aatagaagtc taccttacaa
       61 atgaaaacta tattgtttat aaattttatt ctggtcttga tgcactaaac tgcattaatt
      121 taaatgaatt tgaccttgca attttagatg ttatgttgcc aggagtaaat ggattttctt
      181 tatgccaaaa aatccgagaa aaatatactt atccaatcat tatgttaaca gctaaggatg
      241 aagaaacaga caagattaca ggcttaactt taggtgcaga tgattatgtt actaaacctt
      301 tccgaccttt ggaacttgtt gctagagtga aggcacagat tagaagatat aagaaataca
      361 gtggaagttt acaatctggt gaagaacttt cacatatttt ttctttttta ggtctggaat
      421 tgaataccca aacatatgaa tgccatttaa atggtaaagc tctttcactt actccaacag
      481 agttttctat tctacatgta ttattgaaaa ataaaggctc tgtggtaaat tcagaaaatc
      541 tttttcatgc tatctggaaa gatgaatatt acaataaaag taacaatact ataacagttc
      601 atattcgcca tcttcgtgaa aaattaggtg atactgtaga tgaagcaaaa tatataaaaa
      661 caatttgggg tgttggttac aagatttgac acctattttt cttgtcaaga agggatgtag
      721 tattatgaaa aagattaata attttactta taggaaacta agagataaat ataaatttat
      781 aaaaagagaa aaaaatacag aggcgtattt aaagtataaa ttatatataa tgttagctat
      841 ctatacaggt atagtattgg ttttaatgtt tatggctgat tatacgtttt caaatttttc
      901 aaatcctctt gttaaatggc ttaagttgag aagagatgta ttattttttt tggtttttat
      961 aattggatat atcactattt tcaattttta ttggaaaaaa ccatggaatt atttaagaga
     1021 aatcatcaat gcaacacata ctatttatca acaaaatgat gaattggttg aactatctaa
     1081 gccattaaag gaaatagagc aacaaatgaa ccaaattaag atgtctgttt tgttaagtca
     1141 acaagcagtg aaagaggctg aaaataaaaa gaataacctt gtgatgtatc tagcacatga
     1201 tataaggaca ccacttactt cagttattgg gtatttgagc ttattaaaag aaatacctaa
     1261 tatggataat tctcaaaaat ctaagtatac tgaagttgca cttgacaaag cacaatattt
     1321 agaaaaactt atcaatgaac tttttgaaat aacacgatat aattctaatc aaatcaaaat
     1381 taatttcgaa aaagtagacc tatattatat gttacttcaa ttaaaggatg aattttaccc
     1441 attgctgtct gaaaaaggaa atagagccat tctaaaagca aatgaaagtt taacaataaa
     1501 agcagattct gaaaaacttg caagagtatt taataatatc ttgaaaaatg ctattgctta
     1561 cagctatcct aatacagaaa ttattatctc agcggttcat aaagacagca aggtagatat
     1621 tgcttttaga aattatggac agacaattcc ggaagaacaa ctttctgcta tatttgaaaa
     1681 gttcaatcgt ttagatgaag ctagaaaatc tgatatgggt ggtgcaggtt tagggctttc
     1741 tatagctaag gaaattataa atttgcatgg tggtgatatt actgttcaaa gtaaagatga
     1801 agtcacaaca tttactatat cgcttcctac atctacttag taaaatataa atcaaatatt
     1861 aggattttct taagaaatta tctatttaat attaaaatta tgagtgcctt tgtttagtaa
     1921 aataaatact gagcaagaca cttttgtttt tgcaggtaag tagataaaga gaggagtttc
     1981 aaatatggaa ttaaaaattg aacatgtgac aaaaaaattt aaggataaaa ttgctgtaga
     2041 agatgtttgc cttaccttaa caccaggtgt gtggggattt ctaggagcaa acggagcagg
     2101 taaaactacc ttgatgagaa ttattacaga cattatgaaa cctaccaatg gcaaaattct
     2161 gtataatgga aaaaatattt atataatggg tgctgagtac agaaatttac tgggattttt
     2221 accacaagaa tttggtttcc cacaggattt ttctgtaaaa gattatttag aatatatagc
     2281 agcattgaaa gatgtaccac caagagaagt aaaaggaaaa attaataatc tattggaaat
     2341 tcttacatta tctgatgtaa aaaataaaaa gattattaaa ttatctggtg gaatgaaacg
     2401 acgagtggga attgcacaag ccatgttaaa tgaccctaaa atccttataa tggatgaacc
     2461 aacagcaggg cttgaccctg gtgagcgagt gagatttcgt aattttattt cagaattttc
     2521 tcataatcgt gttgtcctaa tatctactca cattgtatct gatattgagt acatatcaac
     2581 tcaaaatgct attatgaaaa gtggaaaaat tcttgatgtg ggaacaaccg ataaactggt
     2641 taagaaagta gagggcaaag tatgggaatg tcttatatca aatagagata tttcaaaata
     2701 tgaaatgaat ttacgtataa tcaatcagcg tagtgaaaaa aacaatcaag tatctattcg
     2761 ttacttggca gaaaagtcac aaattgataa ctctattgct gttgaaccac gactagaaga
     2821 tttatattta tggttatttc cagaagcagt ttatagtaag gaggggaaat aaatgcgtat
     2881 tttttatttg gaaattaaac gagtgttgca ctcacgtcgt acattaattt tattattgtt
     2941 ggcattggtt ttatctgcat tgatggcttt tcttccaatt acttacgagg gtatcaatta
     3001 tttagatgat aatggcaagg tagttgaatt gagtggttta gatgctatta aatataaaaa
     3061 aacaatttat gctaataata gtgaaattag tagtggagtt gtaacaccaa aaaaattaaa
     3121 gcatgcttta aatatatgga aaaaaacaga agaaaagtat ggtaaagtag gtagtgaaga
     3181 ttttccacta gatatttatt ctaaaagtat tttaccaata cgcccattgt tgaatagact
     3241 tcctgaagca tttgctaatt cagaaacagg atttgcaaca gaattatcag aaataaatac
     3301 aaatgattta gattcttttt atgaacaatg caaaactcat ttaaatgata ttatgaagat
     3361 tgaacgacaa acttccagtg cacaaatgaa agctcaagaa ctttatagaa aagtagatac
     3421 tccatttgag atatacccag gttattctaa agatgctttc gattatataa tattttacat
     3481 ttttatatta ttaattatat gtgttgcaat tactgcacct actttttctg gtgagtatca
     3541 gacacaatca gatagcatcc ttcgttgtac gaaacatgga catactcgtc tagcgtttac
     3601 taaaatatta gttctatttt ctatatttat agtaatgttt gttgtatgta tttctatcca
     3661 tttggcaatt tctgatttag cttttggtac tgaatgtttg aaaacctcat ttcaaatgtt
     3721 gttttctgtc attagtctag taaatataaa tttactacaa gcacagattc ttatagctat
     3781 tggtggtcta atttcaatac ttgcaatggt tagtttaaca ttatttttat ctgcaaaatg
     3841 taaggattct cttacttcta tgctgattgc tttttctatt tgcttaattc ctatgggaat
     3901 aggtgttagt tggattggat acctattacc accaggggga attggtctta agattagttt
     3961 attatatcaa atgacatcat ttaatttctt acacttagga ggtatgagtt tttggacacc
     4021 acacattata ctgtttttct cagtgataga aatacctatt tttatatttt tggctattcg
     4081 tacctattgc aaacatcaag tatcataaca atttgataga aataatagtg atataaacta
     4141 gaggatacaa taattatata tgtagtataa aagttaaatt tagttaacaa atcttaatag
     4201 cagatatagg taataaatta tacataaact gtattattat ctatatctgc tattttaata
     4261 tagagaaaca acagtatatt gtaaagtaaa tgtcaaatat agttttaaaa gtaaaattaa
     4321 tgttaaaaaa gtaaatataa ttttacactt gcttaactta atcctaatat agatttaact
     4381 taaaaaaagt agaataaaag tacaggaaat ttgatgaaga cgaattataa aaaattaaat
     4441 tttgaataca gaacgaaaat cgataagtat attttaatgg gagggtatta tgatagtaaa
     4501 atctagatta gtaggtttag aaaaaaatga caataatggc aataagacaa aatacgtaat
     4561 tgaaaaagta gcaaaaaata tttttctact tagtgcttta gtagcagttg caagtttact
     4621 tttgataata ggattcgtat tttataaagg cttaagacca tttatatttg aaggatattc
     4681 atttatagac tttttaactg gtgcagattg ggttccttct gccaataaat ttggaatatc
     4741 atctatgata gtagcatcaa tatttgcaac acttggagca cttgtgatag gagtacctgt
     4801 tggtatatta acctctgtat ttatagcaga agtagcacct aaaagattag caaaaataat
     4861 gtcaccagca gttgaacttt tagcaggtat accttcagta ttatatggtg tatttggtct
     4921 tgcagtgata gttccaacta tacaaagtat atttaatctt ccaaaaggtc aaagtttgtt
     4981 agcaatagta atagtattag cagtaatgat gttaccgaca ataatatctg tatcagaaac
     5041 agcaataaga gcagtaccaa aagcatacaa agaaggttca ttagcacttg gtgcatcaaa
     5101 aatagaaaca atattcaaag ttgtactacc tgctgcgaaa tctggagtat tagctgcagt
     5161 agtattagga gtaggaagag ctttaggtga aacaatggca gtaatacttg ttgcaggaaa
     5221 ctcaccagtt atgccaactg caataacaga tagtgtaaga ccacttacaa ctaatatagc
     5281 acttgaaatg ggatacgcat ttggtacaca tcaagaaatg ttatttgcaa ctggagtagt
     5341 attgtttaca tttatattaa ttttaaactt agttttaaat aaactttcaa ataaggcggt
     5401 aaattaagat gagaaagttc aaagagaatc tattgaagtc attagtatat ctatcagcac
     5461 tatttacaat agtatcatta gtcattatag tgggatttat atttataaag ggaattggca
     5521 acatgaattt taatttctta tttagcaatt attcagcatc aggtgatggt ggtatacttc
     5581 caatgataat tacaacatta tatacagtag tagtttctat agttgtagca actcctatag
     5641 gaatattggc tgctatatat ttacaagaat atgctaaaaa aggaaaagca gttacagcta
     5701 taagatttgc aactgaaagt ttatcaggga taccatctat agtatatgga ttatttggag
     5761 gaattttctt tgtagttaca ttaaaaatgg gatattccat agttgcaggt tcacttacag
     5821 ttgcaataat aatattacca gtaataattc gtacaacaga agaagcttta aaaacagttc
     5881 ctcaagctta tagagaatca tcattggcat taggagctac aaaatttcaa actttatata
     5941 aggtagtact tccaagtgca ataccaggaa tcttatctgg agtaatctta tcagttggtc
     6001 gtataattgg agaatcagct gcaatattac ttacagcagg tactgtagcc aagatgccag
     6061 gtggaatatt tgatagtgca agaacattaa ctgtacactc atacttactg actaaagaga
     6121 gtggagatat agcaacagca gccagtatag gaattgtttt aatagtaatt gtattagcac
     6181 taaacatgct agcaagattt gttgctaaga aattaaataa agctaattat taaatttaag
     6241 aggtgtgaat aatggaatta atcgataaga taaaaatgag tgtaaaagat ttggatttat
     6301 tttatggtga taagcaagca ttaaagaaaa taaatatgga tataaaagag aataaggtta
     6361 ctgctttaat aggtccatct ggatgcggaa aatcaacttt tataagaacg ttaaatagaa
     6421 tgaatgactt aatcgaagat gtaacaatta aaggaaacat ttctgttgat ggagaggaca
     6481 tatatacctc agatgatgtt ataaatcttc gtactaaagt aggaatggta tttcaaaaac
     6541 caaatccatt tcctatgagt atatatgata atgtggcata tggtcctcgt acacatggac
     6601 taagagataa gaagcaatta gataaaattg tagaagaaag cttaaaaggt gcagctattt
     6661 gggatgaggt taaagacagg cttaaatcat ctgcactagg actttctggt ggtcaacaac
     6721 agcgtatatg tatagcaaga gcaattgcta tgagaccaga agttattctt atggatgaac
     6781 ctacatctgc tttagaccca atttcaacat taaaagtaga ggaacttata gaggatttaa
     6841 aaaaagacta cacaatagtc atagttacac ataatatgca acaagctgct cgtatatcag
     6901 atgaaacagc ttttttctta aatggagagg ttatagaatt tagcgataca aaaactatgt
     6961 ttaccactcc tgtagataaa agaacagaag actatataac aggtagattt ggttaaaata
     7021 tataactata aaggagttag acaatggtca ataatagttt agatataagt attgatactt
     7081 taaaagaaca aacagtactt atgatggaaa aatgtgaaga agcaatagaa aagtctgtga
     7141 cttgtatgat agagaaggat ttagagggtg caagaaaagt agtagaagat gatgaagaaa
     7201 taaataaatt aagagaagaa ataagagata agagtataga gctaatagta ttaaagcaac
     7261 caatggcaag ggacttaaga tttatttatt cattaggtaa tatatcgata gagttggaaa
     7321 gaataggaga ttatgcagca aatatagcta gagaaatgtt gaagataggt ggagaggctt
     7381 atataaaaga gctgatagat attcctaaga tggcaaaaga atgtaagtct atgatgtctc
     7441 agactagaga agctttaatc ttatttgatg caagtatagc ttatgatgtt ggaactaaag
     7501 atgatattgt agatggattg tatgaacaag tacaaattga ttgtttaaaa ataatgcatg
     7561 aaaattcaaa tactatagac caaggagtaa aacttctact tataggaaga taccttgaaa
     7621 gaattggaga ccatataaca aatgtatgtg agaagataat ttttgcaatt gagggtaaaa
     7681 tggttgagat aggataaaaa actgctttaa agcagttttt ttattgtcta aattaagaaa
     7741 gaattgataa aaaaatatga ttaatgggta aatttaaaaa attgtgatat actaggaaca
     7801 tattaaatat gaggatgcgt attttatata aggtgctttt taggaggtgg aactttgaaa
     7861 cttcaaaaga tgggtatgag gactataaaa acaggaatta gtgtcacttt atgtatgatt
     7921 cttggtgact atctagtaga gaatatgttt tattctctag tagcatgtat aatttctgtt
     7981 caagatacgg taaaaggttc tttaaagaca ggaatcaata gagtggaagg tactatttta
     8041 ggtggtataa taggattcat atttgccatc attaaagctg gagacccttt tttatgtggt
     8101 ctaggagtaa tgtgctcaat atatttatgc aatctgttta aaataaagtc agtagtagtt
     8161 gcctgtgtaa cctttctggc tatacatcta ggtgtaggaa atagtgaccc tgtgtattat
     8221 tctttacata gagtgttaga tacatctgta ggtgttttgt ttggagtact tgttaattat
     8281 tatgtggcta gaccaaatta tctaaatagt gttatagatg aatttaaaaa gatagaagaa
     8341 ctttcaatgt tacttattga agataaaatt cttagaaaag aaaatttaaa tgtagagaaa
     8401 tttgaagaag aagtagaaaa attagaagaa atatattcaa aacttattga tgagttggat
     8461 tatagtttga gtgaaactaa tatagaaaaa attgagaatg ccttaaggat atgtagagaa
     8521 atacattttc atatgcagtc tatagagtta cttgaaaata aactttattt gaaagagcat
     8581 acatataaat accttaagaa aacatataat gtggataagc tagactggaa tatagatgaa
     8641 gaaaaaagcc ccgtattcaa ctatcatcta atgaaaataa tgattgaaat agagttgttg
     8701 agaaagctaa ataaatcata ttaataatag tagttaaata ataaataaaa aatagtatct
     8761 ttgtaaatat taaacatata taagtttaat ttatggaggt actatttttt atgaatacta
     8821 gaaatgacaa ttctaaaata ctagaaatat ataaaatgaa gctttttggt gaacttgtaa
     8881 aagcagtgtg gaatgatgat atagaggata ttgaaaactt acctaataaa attttaaatg
     8941 aagatttaaa ggataattta aataattatt ttagtggaaa atttgataaa gatactatgg
     9001 taaatttaat tagggtaact atgggattgg atgtgacaga agatacagat aaaaatttaa
     9061 aagagtcact acatgaagct gtaaatttag atgaagtcaa aagaccaata atatctgtaa
     9121 tatcagatgc ttgcaaatat tgtgatgaaa ataataagga agatgagtca tgtaagataa
     9181 gaagtaagca tattaattgt aatgaggaag atgtatgtag tgcttgtggt gattgtgtat
     9241 caagatgtaa gttgggtgca atttcagata aaatagaatt tataccaatg ataaaattgt
     9301 taaaagatat aaagagccct gtatatgcaa tagttgcacc agcttttgta ggacagtttg
     9361 ggaaagatgt aagccctggt aaattaagaa ctgcattaaa aaagatagga tttgaagata
     9421 tgatagaagt tgctttggca gcagatatgc ttactgcaaa agaagcatat gattattatg
     9481 aacatatgaa aaaggacgaa gaaggatgct ttataactag ttgttgctgt cctatttggg
     9541 ttagtttgat acaaaatagt tttcctcaga tattggagaa tgtatcacca tccgtttctc
     9601 ctatgattgc ttgtgggaga gctgtaaaaa ttttaaatcc agatgctaaa gttgtattca
     9661 taggtccttg tatggcaaaa aagaaagaag caatgttaga agatataaaa gatgcagttg
     9721 attttgtgct tacatttaaa gagttgcaag aaatatttga tgcattagag ttaaatccag
     9781 caataatgga tgagagtaat agagtagagg cgtccctttc aggtagagtt tatgctagaa
     9841 caggaggtgt aagtaaagca gttaagttat cagttagaag aattgacaaa aatataaaat
     9901 ttgaagaaaa ggcatttgaa ggaacaaaag agtgcatgga cggtctaaag aaagttctaa
     9961 ataaagaaat agaagctaca tttatagaag gaatggggtg tgtaggaggc tgtgtaggag
    10021 gtccgaagcg tattttaagt gtggaagaag gtactaagaa tgttgatgaa tatagtgaaa
    10081 gtacgaatat ggaaactcca tttgataatt taaatgtatt acaattttta acttctttgg
    10141 gaatcaaaag agtagaatct ttaggagaaa aagaagaaga aaaggttaaa aaaatattta
    10201 gtagagatat aaaaagtaat aagaaagaga ataaatataa aaaataactt tttaagtctt
    10261 aaacttatgc ttttataaaa gggagatatg ggggatgaaa attaaagata ataaggctgt
    10321 ttttcatgta tttataagga tatttcttat agctgtttta attttaactg gaacattatt
    10381 ggaggaaaaa attaataatg ttccagttga aaatataagt tcaaaaggtg aaaatacact
    10441 ggaactgctt tctcaaagta atactttagg agaaatcata tacaaagcat ctcaagaaga
    10501 aacaaaaggt ccaggggcta cttctgaaaa agtagcatac ataacaatag atgatggtcc
    10561 atcaaaatat acaaatgcac tacttgatat tttaaaagaa aatgatgtca aagcgacatt
    10621 ttttatgctt aatcaaaata tgaaaaatca caaggaagaa gtaaggagag tcttggaaga
    10681 ggaaaactca ataggttttc atagtgtaag tcatgatata cataagttat ataaaagccc
    10741 agaagtaaca gttggggaat ttaatacatg caataatact ctacaagaaa taactggtca
    10801 gagttcaaaa ttaataagat taccatacgg aagtaaacca tatatgccag aaggttcata
    10861 taataaactt atggcaaatg attatttaat ttgggactgg aatttggata cacaggattg
    10921 gaagtcttct acaagtcaga tagtaagtaa tatattatat tatggaagaa aaagagatga
    10981 attagtagta ttaattcatg agaaagagca aagtttaaat gctttaaata atattataag
    11041 aatcttaaaa gagagaggat atacaatatt gccaattaca gaaaatataa cacctaaaaa
    11101 tttctggcaa gaaaacttat aataaattta aatatagtaa aagataaagt aaattattta
    11161 taaaataaaa catataatat aaaaaatacg aataagaggt atactgtaag gataatataa
    11221 tataaaatta atgagaaagc attaaaatta aaataaaata atcttgcaat tattgacatt
    11281 ataagacaga ataactgtaa aaacatattt taaaatataa caactatata aaagagaata
    11341 gacataatta agaaaattca gaaaaaataa aataaaaata attgacaaag agaataatat
    11401 ttgtatataa taatatgtaa tattaaagac tgagaagaag aggagtaagt aaatactact
    11461 aaaagagagg aaaattcact ggctgtaaga ttttctaagt ataagattta ctgaatgtag
    11521 ctttggagtt tctaaactga actataagta agtttagacg gttagaaccg ttaaattctt
    11581 tgagagtcaa agttgataaa ataacattaa ctaataattt aattatatgt taatgtattt
    11641 taagctttgg aattaaggtg gtaacgcgag cttttcgtcc tttttaaaga ggatgaagag
    11701 ctctttttta tttctaaaga tatttaaaaa atttatttat aaaatacagg aggcaggaca
    11761 atggaaaata cgaatttatc aaaaacttat aacccaaaag attttgaggc taggctatat
    11821 aaaaaatgga tggatgaagg gtattttaaa tctaaaccaa atccagataa aaaaccattt
    11881 acaataatga tgccaccacc aaatataaca gggcaattgc atatgggaca cgctcttgac
    11941 catacacttc aagatatatt aatcagatgg aaacgtatgg atggatatga agctttttgg
    12001 cttccaggaa ctgaccatgc ttctatagca acagaagtta aagttgttga aagaataaaa
    12061 aaacaagaag gcaagacaaa gtatgaaata ggtagagaag aatttttaaa gagagcctgg
    12121 gaatggaaag atgaatttgg aggaaaaata tctaatcagc ttaaacaact aggtgattct
    12181 tgtgattggg ataaagaaag atttactatg gatgaagggt gtaatgaagc agttatagaa
    12241 ttttttgtaa gcctatatga aaaaggtcac atatacagag gaaatagaat aataaactgg
    12301 tgcccagatt gcaaaactac tttatcagat gcagaagttg aacatgaaga acacgacgga
    12361 aacttttatc atataaagta cccactaaaa gatagtgaag actttttaga aatagctaca
    12421 actagacctg agacaatgat aggagatact ggtatagcag taaatccaga agatgataga
    12481 tataaacatt taataggaaa aacagcaata cttccattag taggaagaga acttccaata
    12541 gttgcagata gttatgttga tttagagttt ggaactggtg cagttaagat gactccagca
    12601 catgacccta atgattttga agtaggatta agacataatc ttgagcagtt aaatactatg
    12661 aatgaagatg gaactatgaa tgaagtttgt ggaaaatatg aaggtatgga tagatttgag
    12721 tgtagaaaag ctatcgtagc agacttaaaa gaacaaggtt acctaattaa gataaaagcg
    12781 cataatcata atgtaggaac ttgttataga tgccatacag tagttgagcc tagattatca
    12841 gagcaatggt ttgttaagat ggaagaactt gcaaaaccag ctatagatat tcttaaaaaa
    12901 ggagaattag aatttgttcc agataaattt gataaaactt atttacaatg gctagaaaat
    12961 ataagagatt ggtgtatatc aagacaatta tggtggggtc atcaaatacc agcttattat
    13021 tgtcaagagt gtggagaaat agtagttgct agaaaaatgc cagataagtg tcctaaatgt
    13081 ggaagcactc attttaaaca agatgaagat gccttagata cttggttcag ttctgcatta
    13141 tggcctttct ctactctagg atggccaaat aagactgaag ctttagatta ttattatcca
    13201 acaagtgtac ttgttacagg atacgatata atattcttct gggtagttag aatggcattt
    13261 gcaggtatgt tctgtatgaa tgaaaagcca tttgaccatg ttttggttca tggattagta
    13321 agagattctc aaggtagaaa aatgagtaaa tctttaggaa atggtataga cccattggag
    13381 ataatcgagc aatatggagc tgatgcccta agatttacat taacaactgg aaattcccca
    13441 ggaaatgata tgagattcta tatggaaaga gtagaatttg ctagaaactt tgcaaataag
    13501 ttgtggaatg catcaagatt tgtatttatg aatattgatg aagatataat taaaaacatg
    13561 actagagaaa gtgttaaaga ggacttaact ctagctgata aatggataat atcaagagca
    13621 aataatattg taaaagaagc aactaataac atggataagt ttgatttagg aatagcactt
    13681 caaaagatat acgattttac ttggtcagaa tactgtgact ggtatattga aatggttaaa
    13741 cctagattat atggggaaga tgcaaatgct aaatctgcag cattatatac attaacttat
    13801 gttcttgaaa aaatattaaa attattacat ccatacatgc catttataac agaggaaata
    13861 tatactcatc ttcctactgt tgaaggatgt ataatagtat ctgaatggcc aaaatataat
    13921 gaagaagata acatggctga agaagaagat atgatgaact tattgatgga aggtataaga
    13981 agtataagaa atgtgagagc agaaatgaat gtaccacctt ctaagaaagc taaattgata
    14041 ataatcccaa gtgaagaaaa aatagaagct attgagcttg gtaaagacta ttttataact
    14101 ctagcatctg cttcaaatgt agagatagca aaagataaat ctaatgttcc agaagatgca
    14161 gttggagtag ttattgatgg tgttgaaata tttatacctc ttaatgaatt agttgatttt
    14221 gaaaaagaaa ttgagagatt gtctaaagaa aagaaaaagt tagaaggcga aataaagaga
    14281 gttaatggaa agcttgcaaa tcaaggtttc ttagcaaaag ctcctgaaag tttaattgaa
    14341 gaagaaaaag taaaaaaaga aaaatttgaa gagatgatta aatctgttga ggaaagatta
    14401 acaaatttag aatctaaaat aaaataaata taagaattag taaaaacata caaaaagtat
    14461 atattctata ctttttgtat gtttttcttt atatatatac aaatatgatg ttataattct
    14521 ttacagatgt gttatatttt tattttatgt tgtgaatata tgaattttat gtcttaaaat
    14581 ttataagcaa taaaaatttg atatattatg atgtttaata tagggtaata aatacatatt
    14641 atatttattt tactatattt ttttacataa tatatctaga aaagtatagg aatttatcgt
    14701 aatttaagtt taaatattaa agagaatttc tataagtagt ttaatcgaca acttaaattt
    14761 ataaagaaat ttaaatttga aagctagtga gtacagtttg gaaattgaaa taaagtaaac
    14821 taaatgatat tttagatttg gaggtgatat tatgttcagg gtagttatat gtgatgacga
    14881 aaaaatacaa agaagcatac taaaagagtt tacagaaaaa cttttgtctg aaagatgtct
    14941 aaattatcaa atactggaat tttcctgtgg agaagattta atatccaaat acccagaaaa
    15001 aattgatatt atatttttag atatccaaat gaaagatatc aatggaattg aggtggctaa
    15061 aaaaataaga aagtttgatg aaaaagtaga aattatattt acaacagctt tttcagagta
    15121 tgccccccaa ggttatgagg ttcgtgctta tagatattta gtaaagccta tagagtatag
    15181 taactttgca atgggtgtaa atctttgtat tgataacctt caaagaaaga aggagcgtta
    15241 tatagtttta aatagtaaaa aaggatttaa tagaatactg atagattcta ttttatatgt
    15301 tgaaactgta aagagagatt tagttgtaca tacaataggt agagattata aagctaatat
    15361 gagcatgaaa caagcagaaa aattactgtg tgaaaatggc ttttttagat gtcatacaag
    15421 ttttattgtt aatttaagaa gaatagaaga tcttagggat aatatgatta ctattaatga
    15481 acaatttata cctataagta agtatagact taaagattta aaagtagcat taacaagctt
    15541 gttatgtgat ataatgtatt aattttaaaa aggtaattga aaatatcgta aaaaagattt
    15601 aatgtcatca cagggctatt gattaaaact gtcttaatat ataaaatgtt atttatatta
    15661 agacagtttt attatgcaaa atatcagttt atagactttt aatattgttt aatatgtata
    15721 tgtagagttt ccattacagt agcatgatta ttaattagta gcctgattat taatatacta
    15781 ttattgattt ttatatgcat tatatgtatt tttagaatat gattaccttt ttaaaataat
    15841 gactatttat aaaactctat agatatttgt ttcatttagc tatgcatact ttaattaatt
    15901 atattaatat ttaatggagt ataatataaa tattaaagcg acatcttata gtttattgaa
    15961 cctatagtaa tgaattaata aatggtttaa ttctatgaaa agatttcctt ttatgcaatt
    16021 tatttattga aatatgatat aatatataaa ggtgtaagta ttagttgtta aaataatatt
    16081 tatattagtt tttatgcata cttggtataa gtttttcata tattgattaa aattgatgtt
    16141 gatttattat ttttagtatt ttttcacctt ttgattcata ctttgtagaa tggtgtattt
    16201 tctaaaactg attataagac aagttcattc aaattagcat ttttatatca tataaataat
    16261 tgttccccct aaataagatt tagatgtata gtattaaaat caaaaagtat aaaataaaat
    16321 tgatgcttaa tcatagataa atattaataa aatatacaag gggattgtct aataaaaaga
    16381 taatctcctt ttttacaaat aatcctaaat tgtgatataa atctaaaaat tttatcttaa
    16441 catttaacca tttaatgata ataattgata taataaatat aaattaaata tatggtgtac
    16501 ttattttatg tttttagcaa gaaatatagc atttaaaaga taaattgtgc aacttaaatc
    16561 aaagtttaag atgaactatt aacatagata tattaaaaac ttttgtaatg gagaatatat
    16621 gtgatatgaa taataaagtt aaggttgcag tattagatac aggaatagac aaagaacatg
    16681 attacttaaa agataattta gttggaggaa ttgcttttga atgtatgcat gattatatct
    16741 ttatatcaga taaatttgat gatgaagatg gtcatggaac tgcttgtgca tcaataataa
    16801 agaaagagta tgaagatgta gagctatttg taataaaaat tttgagaaaa gatggtatta
    16861 caaatataaa agttcttgaa gaagcattaa gatacctttt agacactaac ataagattaa
    16921 ttaatttaag tttatcagtc ataggagtag agagtgttaa gggcttattt gaagtttgtt
    16981 acgaattgtt tagaaaagga aaaataatag tatgttcact cgctaatgat tttgatttaa
    17041 gttatccagc tatgtttaac aatgttatag gtgtaagagg atttacttta gatggagatg
    17101 attcattttg gtacaacaaa aaatatgatg ttcaatgtgt tatggatagc aattcatata
    17161 taagttgtga tataaataat tcctatagat taccaccaaa atgtaatagt tatttatcag
    17221 caaagcttac tggtaaaata gctaagatat tatcagaaaa accaggcata acaatatctg
    17281 atttaaatga taagcttgaa tcattagcaa ctagaaatca ttgggatagt tgtgattttg
    17341 atgagtgtag tagaattgta aactttaaat tggatttgta tgacaaagaa aatgctcttc
    17401 ttatgaaagt tgctgacgtt gttagggatt gtttagatat tgaagataat aatgaaaaac
    17461 tctttaaggg tagccttttt aataaggaga taggtttggt ttatgataat tgttttaatc
    17521 tgttgaaaaa gctagagcat agatttgaca taaagtttaa ttatatggac atctcaaaat
    17581 atgacttagt ttcaatatat acactgactg aattagtgga aagatataaa aacttataaa
    17641 taaagatttg tagctaaatt taatgtagaa gatattaaat tatatgtatt ctttgtcggt
    17701 agattaaaag taaaaaatat actataatta gatagcataa gagaaaatgc caatacaggg
    17761 ggagttagat aatgaaatat gaagaagcat tagagtacat atcacaaact aataaattcg
    17821 gtataagatt aggattagaa aatatcggaa agttattaga attattagga aatccacaag
    17881 aaactttgaa tataatacat gtagctggaa ctaatggaaa aggttctgtg tgttcttttg
    17941 tttctaatat actaagagag tgtggatata aagttggttt atatacatct ccatatttag
    18001 aaacttttac tgagcgtata agagtaaatg gacaaaatat accacagaat gatgttgcta
    18061 gaataattga gttaataaaa gaaaaaatag agattatggt aaaagaaggc tatgcatatc
    18121 caacagaatt tgaagtggtt actgcaatgg cattttatta ctattcagaa caaaaggtag
    18181 actttgtggc attagaagtt ggtttaggtg gcagatatga tgctacaaat ataataacaa
    18241 aatcacttgt aagtgtgata gtatctataa gtttggacca tacaggtata cttggagata
    18301 caatagaaaa aatagcgtac gaaaaggctg gaataataaa ggaaaatgga gtagtactag
    18361 tatatgacca gactgatgaa gcgaaggatg ttataaagtc agtttgtaaa gagaaaaaag
    18421 ctaaatatat agaagttgat tttgatgata taaacataaa aaaatcagat ataaattctc
    18481 aaatatacga ttgtactgta atgaaagaaa cttatagaga ccttgaaata aaattgatag
    18541 gtgaacatca aataaacaat tctatcttgg caattagtgt aataaaatat ctaaaagaca
    18601 taaataaatt agcaaatata aatgaagaat ctataagaaa aggacttata aatactaaat
    18661 ggccaggaag aatagaaaag ataaaagaaa atccaatttt tataatagat ggtgcacata
    18721 atgaagatgg agcaaaatct ttggcaaaag cacttgataa gaattttaaa ggtagaaaat
    18781 taaccttatt aataggtatg ttagaagata aagatattga tagtgtttta gagatattgt
    18841 tgccacattt taataaggta ataacaacaa caccaaataa cccaagggcc ataaattcag
    18901 atatattaag agaaaaagta ttaaaatatg tagatgatgt aacatcaaag catgagatag
    18961 aggatgcagt aaattataca ttagaaacat caagtgagga tgatattata ataagtgcag
    19021 gttcattata tatgattggt acagtgagaa ctttagtaaa gaaattataa ttttataaaa
    19081 taaatataca aataaagata taaaaaagag ttgtctaaaa aatggacaac tctttttata
    19141 taaagtaagt ttttaataat tttactgatg tttatataag taattatata gattgacgta
    19201 tagctttaga taattggtct gggcaagaag taccttttcc accacagtca ataccgttta
    19261 atttatcagc aacttcaaga gcattttggc cgattattaa gcttctaagt cctgataaat
    19321 taccattaca tcctcctata aactcagcat caacaatcac attattttca tcaacttcaa
    19381 aaatcatttc tctacaacat acaccacttg gattaaatgt tactttcatt aaaaagacct
    19441 ccattaaata ttatttcttt ttttaacatt aataataata ccaaatatat gcgtaataat
    19501 gcaactataa agcataatac aagctaatga aataatatat tattgtagta tatgtattgt
    19561 agagaggagg ggttatatga aaatctatat ttctaactac ttatcaaaga gtattagcat
    19621 agttgattat tctacacttg aactagaaaa agaaatagta ttagaagata atatatatcc
    19681 acaccatttt tgcatagaaa aagaaaaaaa tttaatatac atacctagtt caagtaatgg
    19741 gatactttat gtcttagatt taagtaatga taaaataatt gatactgtct ctataggagg
    19801 aagtcttagt caagttgtac ttagtgataa tgaattgttt gtggcaaatg aagattctaa
    19861 tagtatatat gtactagata aaaacacatt aaatccaata ggaattattg gagttgataa
    19921 tatgccacat ggatttgact ttgatagaga aagtaaaaaa ttatatgtac cgtgtataaa
    19981 ctcgatagta tgtatagata caattaataa aaatatacaa aagaaaataa atatggactt
    20041 tagagcttgg catatagagc ttgataaaca aaagaaagaa atgtatatat caacacttga
    20101 tggaaagctt ataataatag atgaagtaag catggatata aaaaaggtat tatatgaatt
    20161 tttattacca gtagaaataa gatttaatta tagtggcaaa aaagtttatg ttgctgattt
    20221 gggttataat aatgtaagaa ttttagatta tacaacgagt agatacattg gaaatattga
    20281 aataaatggg attcctcaag gcttagaaat atctaaagat gaaaagctac tatttgtatc
    20341 agatacacaa gaaaattcag taaaagttta tgaaactgca aacaataaat taataaaaga
    20401 aatcaaggta ggaaaagagc ctacaactat aatttgtttg taggctttaa tgtatgtctc
    20461 ttataagtaa atcgataact tctgcataca tataagatgc attatttttc cagttattgc
    20521 aaataagttt tgcttgtttc tctgatgaaa catttagatt taaatctatt aagttagact
    20581 gattttctat gactctaagg ttgacaataa attcattatc actttgtttt acaaaactag
    20641 actttacttg agtatctgct agtagatttt ctttgttaga atctatatac ttgtctattt
    20701 tttcagtaac actagtaggt attcgattaa agaagtattc tagactttct acgcctcttt
    20761 gagtaagagc ataatattct ctgtcagagt ctttatatgt agtcaaaaac ttagattcca
    20821 taagctgaga taaaagctgt tgtaatgaaa aataattcat catctcagtc tctaatacta
    20881 cttgagttat ttgagaatta gttaaatcca ttttaatttt ttctaatata tataaaatta
    20941 aaagtttgtg ataggctaat tcttcagacg agttttcaaa cataaatatc atcctccgtc
    21001 aaactatttc tatatataat atattaaact aatttgtaca aaattaaaag aacaatttgt
    21061 attgtattat taatctttaa taattcatat aaaacaattt tataaataaa tatagagaaa
    21121 cagggctgct aattagcagc cctgttgata cccaggtgtc aaaatttact atttattttc
    21181 cagccatttg tctttcagcc atttcaacta atttcttagt catatatcca ccaacatatc
    21241 cattttctct agctgttaag ttacctttat ctatgttttc atagttagat aaacctattt
    21301 cgttagctat ttctaatttc atttggttta aagcagcttt tgcttctgga actactgttc
    21361 tgtttgaatt tgacatagta aatttcctcc tcaaataatt agtttatgat gtctaacaac
    21421 acttttattt atgtgatgtt aatactaatt tctccaaaat aaaaataata tatacagaaa
    21481 aataaaggta aaaatgtaaa aaatataaaa aaattaaata aatgagtatt ttagagagtt
    21541 taattaggtc aatataggtt ttattttttt agttattgtc ttataaatta aatattacag
    21601 tacttttttg agctgaaaaa aaataaattt taaatataga agaaattatt tcaaaggggg
    21661 aatagtatga aaagagaagt taaaaggact aaagctttga tatatagtgt tttatttttt
    21721 tcattattat tagtgttaat atttgttttt gtttatggaa taaaatacat atgttctaaa
    21781 tctgacaatt caaaaatgcc tatatataaa gttgatacaa atgagaaaaa aatagctttg
    21841 agttttgatg tagcatgggg aactgataat atggatgata ttttaaaaat tttagataaa
    21901 cataatgtaa aagcgacctt ctttttagtt ggtagttggg tggatgataa tgaagaaatt
    21961 gtaaaagcta tagatgaaaa aggacatgaa attggaaatc attcaaacac tcatgccaat
    22021 ttgaaggaaa tatcaaaaga agacataaca aaagagatag aaactacatc agaaaaaata
    22081 tataatataa caggaaaaaa gactaattta tttagacctc cttttgggga cgtaaacaat
    22141 aaagctatgg acatttgtag tgatttaggt tataaagtaa ttaagtggga tgtagattct
    22201 atagattgga aggagcttgg accaaatcat gtaattgaga aagtaataaa agaatctcaa
    22261 cctggttcaa tagttttatt ccatgctaat ataaatgatg tagataacta tttggatact
    22321 ataataagtc gactaaaaaa agatggatac agtctagtca aaatatctga tttgttgtat
    22381 aaagataatt atgtagttga ttccaatgga gtgcaaaaaa ctaagaatta ataagtaata
    22441 aatgtatatt ttaagtaaag ttgtgataaa ttatatagta tatgttagaa aagtgtcgat
    22501 aaaaagacgg tgtctatttt ttgacacttt ttatacatgt atgcaatatc aataattata
    22561 gattaaattg attaaaaaag tgtctaataa ttgacttttt ttgatggatt taaaaattta
    22621 gaagaattaa tgaatgctgt aagacagtat ttccaaaggg tataagtttg tttaaaagtt
    22681 ggcatagaaa ttgctttgtt aataagcgat atgttctata gaaataaaca atatgttaag
    22741 accttataat agaaaaatag cattaacatt atttgaacag cttataaaaa aattaatata
    22801 cttaaggggg cgtactagtt gaacaaacta tattctattt tattaaaaca acacgttggt
    22861 ggtccagata agccagtagt aagtgttgga gatgtagtaa aaaaaggaac tctaatcgca
    22921 gaaccaactg gattaggggc aaatatttat gccagtgtta gtggaaaaat aagtgaaata
    22981 aatgaccaag cgatagtaat tgaagctgat gaagtacaag aagatacttt tgaaccatta
    23041 aaaggagaag gtatacttga cttaattaaa gaagctggag tagtaggaat gggtggagca
    23101 ggattcccta cccatgtaaa attaaacata gatttaaatg gtggaacaat attagcaaat
    23161 gcagctgaat gtgaaccttt attagctcat aatataaaag aaatagaaga aagaccagaa
    23221 atagtttatc aaggtataaa atatgctatg gaagttacta atgctggaaa aggtatgcta
    23281 gcaataaaaa gcaagcatcc aaaagcaata gaagctttca aaaaagtaat aaagccagga
    23341 gacaacatag aagttgcaga actagttgat atgtacccaa tgggagaaga gagagcaata
    23401 gtaagagacg ttctaggaaa attacttgag ccaactcaat taccttcaga ggctaatgca
    23461 gtagtaataa acgtagaaac actaactaga atagtagagg ctgttgagca aaaaagacca
    23521 gttatatcta aaaatataac tgtagttggt caattaaaca gtggaaaaga gtctatagta
    23581 tttgaagatg tgccaattgg aacaactgtc ggagaattaa ttgaaagagc tggtggaata
    23641 aaaggtgaat atggtgaaat aatcctagga ggacctttca ctggtaaagc tactacttta
    23701 gatgctccaa taactaaaac tagtggtggt ataatagtta ctatgccatt tgttaatgaa
    23761 aagagaaaaa tgggtctttt agtctgtgca tgtggaccta atgaagagag aatgagagat
    23821 atagcaacta aaatgggagt tactgatata gtatcagttc aaaaatgtaa acaagctcaa
    23881 gaaattaaag gtgcattaaa atgtgaaaat ccaggacact gtccaggaca agctcaaaaa
    23941 tgtattgaat ttaagaaagc tggagcagaa gttatattaa taggaaactg tactgactgt
    24001 agtaacacag taatgggttc tgcaccaaaa ttaaagttag gtgtatatca tattactgac
    24061 catgtaatga gaacagttaa tcacccatta ataagaagaa taaaaggtga cgtaagatta
    24121 aaaataaaat aatagataaa tagaagttag acatctttag aagtaaaact taaaaattac
    24181 ttctaaggat gttttttaat gtattttgag ggcaatatat agctttaaaa gaaatcaaaa
    24241 aagtgccaaa tgtaaaacta attaaaccat atatatttaa gaagggattg aattggagtt
    24301 gtgaattatg ttagtagaaa ccattctaag tgtttgttat tggtacattt gatatttgta
    24361 tgtaaataca gaaaaaactt tttgctaaga tggatacttt gctttcagtg taggaaatgt
    24421 ttctaaagaa atgattgaaa aatacataca aagtaaggga taggtttaca tccaccaacc
    24481 taaaggtata gtggttttac gccttaattt ataaaaagaa attaatttat attattatta
    24541 agtttaaaat aaaaagtctc aaattgattt ataagtcatt ttgggacttt tttatgtaaa
    24601 tataatatgc aaatatagtt tgtttaaaaa tatctatttt aattatattc ttaaatttat
    24661 gattggatac aggcattcat taattgtttg atgaatagaa aaatgttttg aaggtgaaaa
    24721 tagtattgaa aaaataatat actaagggta taattcattt gatttcattt gtataaattt
    24781 aattata
//
LOCUS       DACTZW010000065        24122 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.065, whole genome shotgun sequence.
ACCESSION   DACTZW010000065 DACTZW010000000
VERSION     DACTZW010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24122)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24122)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24122
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.065"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(244..753)
                     /locus_tag="JAM15_13280"
     CDS             complement(244..753)
                     /locus_tag="JAM15_13280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside recognition protein"
                     /protein_id="HAT6799227.1"
                     /translation="MSQQNTGNTIVNSKPKKTAVEIFMGGAKKGFYIGVEQILPAMIM
                     GYVIVQFLQLTGLVDILGNIFGPVMGIFGLPGESVVVLIAAFFAKAAGAATAANLFAQ
                     GLITAPQATILIMPCMLMGTLVGHYARIVLVANASTKYRMLLLAVPIFDAIVGMLIVR
                     VLLTVMGLM"
     gene            complement(755..1402)
                     /locus_tag="JAM15_13285"
     CDS             complement(755..1402)
                     /locus_tag="JAM15_13285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799228.1"
                     /translation="MDVTAGDNKVTWKGYLSLFVLIVLFSGVFKDSQGFLKALDFANL
                     TGSFGTIADGVDFMGKGGTGAKDGFLFALTLIPTVCFAVGLIDVVESMGGMKAASKIF
                     NPLLRPLLGIPGIAGIAFVSSFTSSDVASIMTKELFESGEITDDERTIFVAYQYAGSA
                     VILNTINTQAPLLPIALLALGPIILIEIFCKILGANLVRLIIGVRNKKNKAKEAV"
     gene            complement(1416..2588)
                     /locus_tag="JAM15_13290"
     CDS             complement(1416..2588)
                     /locus_tag="JAM15_13290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HAT6799229.1"
                     /translation="MNTYLNEISKFVDENREEIVSLWKEIVNIESYTHCKESVNKLAE
                     RLKLEFEKEGLDCELVDVGENGNTLIGTLGSNIDKKPIIFSGHMDTVFETGTFGENPF
                     KIIEGKAYGPGVLDMKGGIIISLYVIKALNKIGYKERPIKIVFSGDEEIGHKDSTGAD
                     VILREAKGALCAFNMETGLVDNSLCIGRKGRIGCNIHVKGVETHAGNDFEGGRNAIEE
                     MANKILRIQKLTNLDVGTTVSVSVIKGGRVENSIPEDCSIKVDLRFEKVEEMENVKEQ
                     VREICKETYIEGTSTEVNFISEMMPFETTEEVMRFHTFVNEVSRENGFGELNAKRLGG
                     SSDASYLTIANVPTICSFGVRGEWNHTSREYAVVDSMFERVKLISTVILNLDKFEV"
     gene            2856..4232
                     /locus_tag="JAM15_13295"
     CDS             2856..4232
                     /locus_tag="JAM15_13295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799230.1"
                     /translation="MKYKIGFLTTSYFMSDKFKQALKELNDTCEITFIELKGENPFNN
                     LPNIYYEQVDNFDGFVCSGIVPYSELIINIKDIKVPLNFLKLDERDFYKYLFKLLNSQ
                     KDIDFTKSFMDFLREDNNYYDIYSLIDSNKCPYTIKDFNIPQPVYDFKKLNDKLLEIH
                     LDLLRDNKINLSFTRNYIISCELNKLGYDCIYMVPSTESILNTFKSLVNEITLQNLDK
                     NKSATCIVTVNSSEYINEDLIFKNDEIQNQIYNTILNSLSRHGFYGVQVKKNDMKIEI
                     HTTKEILNNMTNNYTDFFISEDLKEIKYSLNIGWGIGNTNIHAEQNARQANGKSASLN
                     GNCTFIVNDTNDTIGPLYSNKNSNNIEDSSIANKVASFIPLSNTNVSKIMCMINDRNS
                     NNVSAEILADYMNITLRSANRILSILYKAGIATIVNTKLDNQRGRPKKIYKVDFLSFL
                     NKMQKLNS"
     gene            complement(4483..5316)
                     /locus_tag="JAM15_13300"
     CDS             complement(4483..5316)
                     /locus_tag="JAM15_13300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAT6799231.1"
                     /translation="MTIKEVEEKTGLTRSNIRFYENENLIKPLRNERNGYREYSDENV
                     EDIKKIAYLRTLGITIDDIRNIILQKVSLVEVVEKQEKVLETKISDLENAKTMCNKML
                     ESDELSYLNLKVEQYITELPEYWNKNKPVFKLDSVSFLYIWGGKITWGIITIACLLIA
                     ITVFPKLPPQIPIQWNNGVANYVDKKFIYAYPVICVVFRILLRPFIWRWLQIHAFYSD
                     TIADYLTNFMCFVALSIEIFSILFIYNIARHVTIIIFIDILVFIVLLIIGVYKLFKKY
                     N"
     gene            complement(5645..6175)
                     /locus_tag="JAM15_13305"
     CDS             complement(5645..6175)
                     /locus_tag="JAM15_13305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HAT6799232.1"
                     /translation="MKSLVLYSSLTGNTKKIAYAIYDEIQEEKDIKDVNELVDYGIDY
                     ENYDIVFLGYWVDKGICDKNSKQVLENIHNKKIALFGTMGASKKGSYGASIIEKIESI
                     IPKDNEILGSFICQGKIAEGLKAKYKEMLKLSPDNEHIRQQLNNHEESQSHPDEQEIY
                     EASIFAKNMMIKASIV"
     gene            complement(6263..7357)
                     /locus_tag="JAM15_13310"
     CDS             complement(6263..7357)
                     /locus_tag="JAM15_13310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:flavin oxidoreductase"
                     /protein_id="HAT6799233.1"
                     /translation="MYCNLLKPIKIGNLELKNRVSFAPTSMGLKLEEKIKKFSDIAKS
                     GVALITLGDVSIRPSFHKVAISLSDEDGVIKYKKIVDEIHNSGAKVSAQLFCSDYDVN
                     LIKDTMKMGITSHDEIKKIMNDGVKDYITNMPKEEIKNIINLFKVTALNAKKAGFDMI
                     QIHGDRLVGSFSSSIFNNRNDEYGGTCDNRSRFASEIISSIRDEVKDIPIDYKFAIRQ
                     ENPHYGNAGVLLSEVEYFVKKFESLGVNSFHVTLANHSKLEDTIPTNNHPYFKDEGCF
                     LYLADEVKKHTNLPVCGVGKLSSPDFIESIISNNRVDMVSMSRQLLADSNWLQKVKDG
                     RVDEIKKCCYCNKKCADALQTRSQFGCILD"
     gene            complement(7359..7805)
                     /locus_tag="JAM15_13315"
     CDS             complement(7359..7805)
                     /locus_tag="JAM15_13315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HAT6799234.1"
                     /translation="MDFKNLQYESLSYIICNLQKNFKLYCEKCLKPYKLTNGLYFYLI
                     YINKNRNCSLNDVSTEFEVDKAHTTRTISRLEQDGYIEKIQNPNDSRAFQLRVTDKGE
                     EVLGDIKNIFSKWDNHIKKEFSDTEYKELVKNLHVVKDIKTAVEEE"
     gene            8111..9301
                     /locus_tag="JAM15_13320"
     CDS             8111..9301
                     /locus_tag="JAM15_13320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008429242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAT6799235.1"
                     /translation="MISNKMQTLVANSSVIRAMFEEGKKLSDIYGEENVFDFSIGNPS
                     VEPPETIKAVINDILNEESPNLVHGYMNNSGYEDVRDAIAEHINKKDGLNLTRENLIM
                     TCGAAGGLNIILKTLLNPGDEVIAFAPYFGEYKNYTENYDGKLIEVPTNIETFEPDLD
                     ALKNAITPKTRALIINTPNNPTGVIYSEELLKNLGELLDSKQKEFNTSIYLISDEPYR
                     EIIYDGAKVPCVLKYYRNSFIGYSYSKSLSLPGERIGYIVANGQMDDFDDVMSSLNVA
                     NRILGFVNAPSLFQRVIARSLDAEVDVNIYKKNFDLLYNSLIDMGYSCVKPNGTFYLF
                     PKAPIEDDKKFCNDAKQFNLLLVPGSSFGCPGHFRVSYCVSYDKVKSSLPAFEKLAKL
                     YNLK"
     gene            9471..10433
                     /locus_tag="JAM15_13325"
     CDS             9471..10433
                     /locus_tag="JAM15_13325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HAT6799236.1"
                     /translation="MKKGYVYIILTTLFFSSMEISLKTVTNDFNPLQITLSRFFVGGL
                     VLLPFAVKRLRALSLSITKSDLKYFAFLGFMCVVVSMSLYQLAVLNTKASVVAVLFSC
                     NPVFVMLLAYLILKEKIYRHNVISLILEVLGIIVIINPLHTKLTLSGIFLTLSSAIIF
                     SMYTVFGKRKTLKFGGIVVTCFSFIFGSLEMLILVLLTKINFIADILNKNKLHIFANI
                     PIFSGYTLHNMPIMIYVFVFVTGVGYALYFMAMEATSTSLTSLVFFFKPVLSPILALL
                     ILKEIIPINMVIGILLIVIGSIISIIPTIITQMHNKHVEALYKE"
     gene            complement(10554..11216)
                     /locus_tag="JAM15_13330"
     CDS             complement(10554..11216)
                     /locus_tag="JAM15_13330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease Zmp1"
                     /protein_id="HAT6799237.1"
                     /translation="MRPSKKLLIAIISIFLISSVPVSAHAYSTTIQQNKDTLSQIVVF
                     PTGNYNKNEANAMVNRLANIDGKYLNVLKQNNLKIKLLSGKLTDEKEYAYLKGVVPKG
                     WEGTGKTWDDVPGLGGSTVALRIGFSNKGKGHDAINLELHETAHAIDHIVLNDISKSA
                     QFKQIFAKEGRSLGNVNYLGVYPEEFFAEAFAYYYLNQDTNSKLKSACPQTYSFLQNL
                     AK"
     regulatory      complement(11316..11401)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(11587..14541)
                     /locus_tag="JAM15_13335"
     CDS             complement(11587..14541)
                     /locus_tag="JAM15_13335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021362860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HAT6799238.1"
                     /translation="MKKGNKKALLISLIMILSMVVSTIYPTVSYASELGENSQIQSGS
                     TNSSTGEEKESDNKKPEQTPEKDKATDNKKPEQTPEEDNSTDNKKPEQTSEEDKSTDN
                     KKPEKTPEGEKPIDNKKPEKTPEGEKSIDNKKPEQIPEEDKSTDNKKSEQALEDEKPL
                     DNKNTEKTPEEDNLLEDENLLKVLEEELNEDYGFVVKINNNTIETESMKKISFNLTYT
                     PTSKGIQAGDSITFKVPDVFNKVNLDYTSECFDKTESNGEYTLTFRELPNGQSVMQGK
                     IGLEAYVKKVDEDTNAKIHIETTGKIESGSGDIDVEIKPGDKTDVPDAKGTLKKLVEG
                     KKSTTVFMPVKNKDINYSIQVNEKQEELKDIILYDELPEGLTLINGSVSVVTSDGKEV
                     SDFNIEQSKNSISVNFGNIDKSYTVKYKARISDKNAKHGNKYKNVARIESDGKKIQED
                     DATVSIFDRGDNYLLTKGHSGATNITQVGQVINYQISINDDKSPISNVVITDNIPEGM
                     RLTTSGEDGHDFRVVEIPMNGSWTPWSKEKIANNISYKVEEKRNESGQVDKVITGFTI
                     NLSKEEVESKFFIAYTLKVISIEDSYINRAVLDANNSEIDKNDEINFKKNSGLISAKK
                     EVDKKVLNSSDNQIVKYKINMSTYGVYDAGQVNLLDEVNPSLKISNIKYSDNLELKKE
                     AGDGKNTIRLVNKYEFKQIKEGEPVQSWVTFDANFTNVKVGETIQNVAQINGSSPPGV
                     ETTKQGYAFEAKKVDALDKNVLSGAKFNLEDAFGNIVVKDLVSDEDGIIQSSVKKPGI
                     YYLVEVMAPSGYEKLKDKIKVEIGNKDIGRIVDIGNIENIRQENPPVNPPVPPNTDEP
                     IVNPPVPPSTDKPRKPSNPSDTEDTIVINPPVPPSEDIINPPIPEILNPPVPPSEEVI
                     ETPVKQIIPIPEVVKPSVSEEKNNKAKDDTLVNPPVPPKTGDSTTIIGEILLVIGAIV
                     GLVVLRRNKNTN"
     regulatory      complement(14654..14739)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            complement(14865..16043)
                     /locus_tag="JAM15_13340"
     CDS             complement(14865..16043)
                     /locus_tag="JAM15_13340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAT6799239.1"
                     /translation="MFSKILVKTFIRDSENVQNTDVRNKYGYVAGVVGILSNLLLFVI
                     KVFIGMFTSSIAIMADAFNNLSDMASSAITMIGFKLASKPADKEHPFGHGRIEYLSAL
                     IVAFMVMLVGLQFVKSSIERIVNPIPVKFEVIPLILSIVSIMIKIWLSRFNKFVGNKI
                     DSSALKAVSLDALGDVFTSSCVVISFIVARFTNFPIDGYVGIVVSLVILYAGFSLVKD
                     TINPLLGEAPDEEMVNSIIELLLSYKYIIGTHDLIIHNYGVGRCIASIHAEIPSNIDI
                     MEIHEIIDTAEREISEKLDIYLVIHMDPICLEDKEVMSAKKELEEILKKNSLVKSMHD
                     FRIVGKGSKKNLIFDIVVNPSEFSKDMSEDDLKEDITKLVKEINPEYNCVIVVDKDFI
                     "
     gene            16415..16954
                     /locus_tag="JAM15_13345"
                     /pseudo
     CDS             16415..16954
                     /locus_tag="JAM15_13345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007062553.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
     gene            complement(17026..19800)
                     /locus_tag="JAM15_13350"
     CDS             complement(17026..19800)
                     /locus_tag="JAM15_13350"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HAT6799240.1"
                     /translation="MRYYNKPTKEVLKYLKTNPEIGLDDNEVEERKLRYGLNEFTIKE
                     GRTFWDELGESLTEPMILILIGAAVISSFVGELHDALGILGAIFIGISIGIITEGKSK
                     KAAHALSKLTENIEVKVLRNGKIIKISKNDLVPGDIVYIETGDMIPADGRLIQSINLK
                     LREDMLTGESDDVAKNADAVLDMEVVYSKTEIIEQDAIPAKQVNMVFGGTLVAYGRGI
                     MVVTHTGDKTEMGKIAQNLSNEDQQTPLQIKLGKLGAKIAGISGVIATLLCMFMIIQM
                     QRKGMLILDTSSVLSFLQSLEPAKNAYMVCIALIVATVPEGLPTMINITLAITMQKMA
                     KINALVTKKEACETIGSVSVICSDKTGTLTQNKMMVEVAYVDGKYISGGEYQSNSYFE
                     QNCIVNSTADIEKEDNSFKYIGSATECALLLYHNDKNYNEMRKQTYLISQIPFSSEEK
                     KMSTLIRQEDSDILLSKGAPEVLLKKCSYVQQGKNIVPITPKVEKSILDEIKKLQIKS
                     MRTLGFAYKKMSNSKTEVAMTSEGELNLIGNSRSYMKEDNLVFSGFVGIVDPLREGVK
                     DSIDKAFNAGVDVKMLTGDNINTATAIGNELGLLNDGKKAVEATYIDVLTDKELREEI
                     KGISIVARSKPDTKMRIVSALQKSGEVVAVTGDGINDAPALSQADVGIAMGISGTEVS
                     KNAADIILTDDSFSTIVEGIKWGRGIYENFQRFIQFQLTVNIVAFIIAIISQLTGKDM
                     PFTTIQLLWVNIIMDGPPALALGLEPVRDYVLKRKPINRHSGIIARSMFVNIIINAIL
                     IITIVFTQSAFNILGATSEEQGTVIFSLFAFSALFNALNCREFGLNSTIPNFFKNKLA
                     LQIIVVTGIIQIIFTQVFQSFFNSVSLDFDMWIKIILLASTILLSNEFVKLILRTMKN
                     SRTMNFNSKN"
     gene            complement(19971..21227)
                     /locus_tag="JAM15_13355"
     CDS             complement(19971..21227)
                     /locus_tag="JAM15_13355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HAT6799241.1"
                     /translation="MLKTTKISDPELYKIVADELVRQEHNIEMIASESTAPTEVLELS
                     GCVFTNKTEEGYPGARFQAGSEEADKLETLAIKRAKEVFGAEHVNVQPYSGSTANYCV
                     YSSILKPNDTVLSMRLDQGGHLTHGSTVNFLHDIYKYEFYGVDPNTGRIDYDALEAKA
                     KECRPKLIIAGASSYPRLIDYERISKVAKEVGAYFMVDMAHVAGLVAAKVIPSPVPYA
                     DFVSSSTTKTFCGPRSGIVLCKAEHAKKLDKGVFPGTLGSIHLNTVAAKAFSLLYLST
                     DKFKKIMEQVVVNAQTLASELISHGFSIVSGGTDNHIVMVDLRSKNLTGKQFEKALEY
                     VGITVNKNVIPDDPQSPFVTSGVRIGLTSISQRGLKEKEVIQIAGIMNKVAENIDNKE
                     VLDECKAEAQELISKFPLYPEGYFED"
     gene            complement(21299..22849)
                     /locus_tag="JAM15_13360"
     CDS             complement(21299..22849)
                     /locus_tag="JAM15_13360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HAT6799242.1"
                     /translation="MRKINSQEKNKDSGLLMRALNVVERAGNKLPDPVTIFLLLCIIV
                     VILSAVISNLGVEEIHPSTKEVVKVVNLLEKEQIQSYLGSIVTNFQSFAPLGLVLVTM
                     LGAGVAEKSGFMEVLMKKGISKVPQKLVTVAIVFAGMLSHTAADVGFIILPPLAALVF
                     LGIGRHPLVGMFAAFAGVAGGFAANVMLSTTDVLLAGFTIPAAQMMDPSYQGNPAMNL
                     YFAFISAIVLTFAGAFVTEKFIAPRFTKYNDSTNDKDIQELSELENKGIKYALLSLLV
                     VVVVIVALCIGDNAFMKDPETGSILSSNAPLMKGIVPIITIIFLTPGLVYGKVSKKIK
                     SDKDLVSMMGSSMSDMGGYIVLAFIASQFINLFNLSNLGTILSITGAKLLAESGIPSY
                     GLIIGFILLSGFINLFVGSASAKWAILAPIFVPMFMLLDFNPALTQIAYRIGDASTNP
                     ISPLFPYFPVILAFARRYDKDIGIGTVISNMIPYSVVFTLIEIIILLLFMGIGIPLGP
                     GGGISYVL"
     gene            complement(22892..24082)
                     /locus_tag="JAM15_13365"
     CDS             complement(22892..24082)
                     /locus_tag="JAM15_13365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HAT6799243.1"
                     /translation="MHELILISEKYKEDILDFFTDIHMHPELSFKEFRTTKAIKDLLV
                     SLDIEILDLGMETGVVGLLKGKYDGPTVALRGDIDALPIYEEVDIEYKSRYDGIMHAC
                     GHDIHTSCLVGCAYVLSHIRDSLHGNVKFIFQPAEEVNKGAKMLVERGVMENPKVDAI
                     FGLHNHPDIPCGKIGVKLGGLMAAVDTIKIEVNGFGGHGGIPNRTIDPIVASSAIIMG
                     IQTIVSRNISPLESAVISIGTINGGTANNVISEKVDMTGTCRSFSNEVRKKISENLEN
                     IVCEIARGYQATAKLDYLFDLPAVINSKEMYTIACKSVCDLYSEDAIVDPIPSTGGED
                     FSIFMEKAPGFFYWLGVGNKEQDCIYQWHNPKFKADKNSILVGTNVLCQSVINYMDKL
                     KNKI"
BASE COUNT         7807 a         4152 c         2809 g         9354 t
ORIGIN      
        1 ggattatact aaaatagaga taagcctctc tttcattgtt gaaattatga aaatatactt
       61 gatttaatac caaaagagta tctcatgaac taaaaagttc attttgagat actctcttct
      121 tttttaatta atatacatat taattactat attagtttat tactatatat caattactat
      181 tcattaatta ctattcatca attcttatat atcatttata attaggttat aattttatgt
      241 tatttacatt aatcccataa cagtgagtaa aactcttact atcaacatcc ccactattgc
      301 atcaaatata ggaactgcca acagtaacat tctatactta gtactggcat ttgctacaag
      361 cactattctg gcataatgac caactagagt acccattaac atacatggca taattaatat
      421 ggttgcttgt ggtgcagtga ttagaccttg tgcaaataag tttgcagctg tagctgctcc
      481 tgctgcctta gcaaagaatg ctgctatcaa aactacaaca gattccccag gtagtccaaa
      541 aatacccatt actgggccaa aaatatttcc taaaatatca actaaaccag ttaattgtaa
      601 aaactgcact attacataac ccattatcat ggctggtaat atctgttcaa cacctatgta
      661 aaaacctttt tttgctcccc ccataaatat ctcaacagca gttttcttag gtttactatt
      721 tacaattgta tttccagtat tttgttgact catactacac agcctcctta gccttattct
      781 ttttatttct tacacctatg attaatctaa ctagattagc accaagtatt ttacagaata
      841 tctctataag gattattgga cctaatgcca ataatgctat tggtaaaagt ggagcttgag
      901 tatttattgt gttcagtata acagctgaac cagcatattg atatgctaca aatatagttc
      961 tttcatcatc tgttatttcc ccactttcaa ataattcttt cgtcattatt gaggctacat
     1021 ctgaactagt aaatgaagat acaaatgcta ttcctgctat tccaggtata ccaagcagag
     1081 gtctaagtaa tggattaaat atctttgatg ctgctttcat tcctcccata gattcaacta
     1141 catctataag acctacagca aaacagacag ttggaatcaa agtcagagca aataagaaac
     1201 catcttttgc tcccgttcct cctttaccca taaagtctac accatctgca atagtaccaa
     1261 atgaacctgt cagattagca aaatctaatg ctttaaggaa gccttgacta tctttaaata
     1321 ctcctgaaaa taatactatc aatacaaata aagataaata ccctttccat gttaccttat
     1381 tatctccagc tgttacatcc atataaaatc cccctttata cctcaaattt atctaagttt
     1441 aaaataactg tagaaattaa tttcaccctc tcaaacatag aatctactac tgcatattct
     1501 cttgatgtgt ggttccattc tcctcttaca ccaaatgaac agattgtagg aacgtttgca
     1561 atagttaaat aacttgcatc tgaactacct ccaagtctct tagcatttaa ttctccaaat
     1621 ccattttctc ttgacacttc atttacaaat gtatgaaatc tcataacttc ttctgtagtt
     1681 tcaaatggca tcatttcact tataaaatta acttctgtag aagttccttc tatgtaagtt
     1741 tctttacata tctctctaac ttgttcttta acattctcca tttcttctac tttttcaaat
     1801 ctaaggtcta cttttatact acaatcttct ggaatagaat tttccactct tccaccctta
     1861 atcacactta cacttactgt agttccaaca tctaaattag tcaatttttg tatgcgtagt
     1921 atcttattag ccatttcttc tatagcattt cttccacctt caaaatcatt acctgcatgt
     1981 gtttctacac cttttacatg tatattacat cctattcttc cttttctacc tatacataaa
     2041 ctattatcta ctaatccagt ttccatatta aaagcacaaa gagcaccttt tgcttccctc
     2101 aatataacat ctgcaccagt tgaatcttta tgacctatct cttcatctcc agaaaatact
     2161 atttttattg gtctttcttt gtatcctatt ttatttaaag ctttaataac gtataaagag
     2221 attattatac cccccttcat atctaaaaca cctgggccat atgcttttcc ttctattatt
     2281 ttaaatggat tctctccaaa tgtacctgtt tcaaagacag tatccatgtg tcctgaaaaa
     2341 attatcggct ttttatctat attagaacca agtgtaccta tcaatgtatt accattttcc
     2401 ccaacatcta ctagttcaca atccaaacct tctttttcaa attcaagctt taatctctca
     2461 gctaacttgt ttacactttc tttacaatgt gtataacttt ctatattaac aatctctttc
     2521 cataatgaaa ctatttcttc tctattctca tcaacaaact tagaaatttc atttaaatat
     2581 gtattcataa tcttctcctt tattttcaaa taaaatgtat ttctttccta aaatctaagt
     2641 ttattttagg aaatcttaaa agactagtcc ttaattacaa aatagcacaa ttattcttgc
     2701 cagtcaacat atttttcagt cttttttata ttttctgatt tttctttcaa ttatcctttt
     2761 gtaaaataaa ttgacgcgtt ttatctacta ttataaaatg aggttataaa ttgattgatt
     2821 agttacaata ctctcgaaat tttaaaggag gttttatgaa atataaaatt ggttttttga
     2881 caacatctta ttttatgtca gataagttta aacaagctct taaagaatta aatgatactt
     2941 gtgaaattac atttattgag cttaaagggg agaatccttt taataattta cctaatatat
     3001 actatgagca agtagataat tttgatggat ttgtatgcag tggtatagtt ccatatagtg
     3061 aacttataat aaatataaaa gacataaaag ttccattaaa ttttttaaag cttgatgaaa
     3121 gagattttta taaatactta ttcaaattat taaatagcca aaaagatatt gactttacaa
     3181 aatcatttat ggatttttta agagaggaca acaattatta tgatatatat tcattaatag
     3241 actctaataa atgtccatat acaattaaag attttaatat ccctcaacct gtatatgact
     3301 ttaaaaaatt aaatgataaa ttattggaaa tacatttaga cttattgcga gataataaga
     3361 ttaacctttc ttttactaga aattacatca ttagttgtga acttaataag cttggatatg
     3421 attgtattta catggttcca tctacagaat caatcctgaa tacatttaaa tctctggtga
     3481 atgaaataac attacaaaac ttagacaaaa ataaatctgc aacttgtata gttacagtaa
     3541 atagttcaga gtacataaat gaagatttga tatttaaaaa tgatgagata caaaatcaaa
     3601 tatataacac tatattaaat tctctatcaa gacatggatt ctatggagtt caggtcaaaa
     3661 aaaatgatat gaaaatagag atacacacta ctaaagaaat attaaacaat atgaccaata
     3721 actatacaga tttttttatt tcagaagatt taaaagaaat taaatatagc ttaaatatag
     3781 gttggggcat tggaaataca aatattcatg cagagcaaaa tgctcgtcaa gctaatggta
     3841 aatctgcttc tttgaatgga aactgtactt ttatagtaaa tgatactaat gatacaatag
     3901 gccctttata ttcaaataaa aattctaata atattgaaga tagctcaata gccaataaag
     3961 ttgcttcttt tatacctcta tctaatacaa atgtatctaa aatcatgtgt atgattaatg
     4021 atagaaattc aaataatgtg tcagcagaaa tattagcaga ctatatgaac ataactctta
     4081 gaagtgctaa tagaatattg agtatcttat ataaagcagg aattgcaact attgtaaata
     4141 caaaactcga taatcaaaga ggaaggccaa aaaaaatata taaagttgat ttcttatctt
     4201 ttctaaataa gatgcagaaa ttaaattctt aatatttaat tttttaataa aagcaatgta
     4261 ttttctctaa ttttaaagaa tcaaaatgtt taaattttat tagaatatac aactttttac
     4321 tttaaaatac ctaaaccttt tatcagtgaa ataaaccata atatatcgta gcttattaga
     4381 aaaacaaaat aatttcatat acaaataata aaatagccac tacaatccat aatttgcagt
     4441 ggctactttt tacactatca cttattactt aatttttaaa aattaattgt attttttaaa
     4501 taatttatac acacctatta tcagtaaaac aataaataca agtatatcta taaaaataat
     4561 tattgtaaca tgtctggcaa tattgtaaat aaaaagtata gagaatattt ctatagacaa
     4621 cgctacaaaa cacataaaat tcgttaaata atctgcaata gtatcactat aaaaagcatg
     4681 tatttgtaac catctccata taaatggacg taaaaggatt ctgaatacaa cacaaatgac
     4741 agggtaggca taaataaatt ttttatctac ataattagct acaccattat tccattggat
     4801 aggaatttga ggtggcaact ttggaaatac tgttattgca atcaacaaac aagcaatagt
     4861 aataattccc caggtaattt tccctcccca tatatataag aaacttacag agtcaagttt
     4921 aaaaacaggt ttgtttttat tccagtattc tggcaactca gttatgtatt gctctacttt
     4981 caaattcaaa taacttagct catcagattc taacatttta ttacacatag tttttgcatt
     5041 ttctaagtct gatattttag tttcgagaac tttctcctgt ttctctacaa cttcaactaa
     5101 agatactttc tgtaatataa tattacggat atcatcaata gtaattccta atgtacgtaa
     5161 atatgcaatt tttttgatgt cctctacatt ttcatctgaa tattctctat agccattacg
     5221 ctcattacga aggggtttaa ttaaattctc gttctcataa aaacgaatat tagagcgtgt
     5281 caatcctgtt ttttcttcaa cttctttaat tgtcatttta aacactacct ctctattctg
     5341 ttaatttata actataatat agtcttaaat attttcactc tataaaatag tatatttatt
     5401 atgtcttaaa atcaagttaa ttatctttta taaattttca tacaataata tctcctttca
     5461 ataatatctc tttttctata tttaaaacta tcttattttc tataaaataa tgtataaaca
     5521 aggtttacag tcaagtattt ttattatgtt tttgatttca taaaaaaaag catagcaaat
     5581 catttgctat acttttttac taaattattt attctatgtc ttatatgaac ttattgttta
     5641 actactacac aatactagct ttaatcatca tattttttgc aaatatacta gcttcatata
     5701 tttcttgttc atctggatga ctttgagatt cctcatggtt atttaattgt tggcgaatat
     5761 gttcgttgtc aggagaaagt tttaacatct ctttatattt tgctttcaat ccttctgcta
     5821 tcttaccttg acatatgaat gaacctaata tttcattatc ttttgggata attgattcta
     5881 tcttttctat tatactagct ccataacttc cttttttact tgctcccatt gttccaaata
     5941 gtgctatctt tttattgtga atattttcaa gcacttgttt tgaattttta tcacaaattc
     6001 ccttgtccac ccaatagcct aagaatacta tatcataatt ttcatagtca ataccataat
     6061 caactaattc atttacatct ttaatgtctt tttcttcttg aatttcatca tatatagcat
     6121 aagcaatctt tttagtattt ccagttaaac ttgaatataa aactaaactt ttcatgatgt
     6181 ctcctcctct ttatctaaat acttatctaa atcaccaaaa atatattaac cttaacaaat
     6241 tatttatttt tataaagata ttctaatcta gtatacatcc aaactgagag cgtgtttgta
     6301 aagcatctgc acacttctta ttacaataac agcacttttt aatctcatct actcttccat
     6361 cttttacttt ctgtaaccaa ttactatctg ctagtaattg tcttgacata gaaaccatat
     6421 ctactctatt atttgaaata atactttcta taaaatctgg gctagacaat tttccaaccc
     6481 cacatactgg aagatttgtg tgtttcttta cttcatcagc taaatataaa aaacagcctt
     6541 catctttaaa gtaaggatga ttattggttg gtatagtatc ttctaatttt gaatgatttg
     6601 caagtgttac atgaaaactg tttacaccta gggattcaaa ttttttaaca aaatactcaa
     6661 cttccgaaag taaaactcct gcatttccat aatgaggatt ttcttgtctt attgcaaatt
     6721 tatagtctat tggaatgtcc ttaacttcat ctcggatact actaattatt tcgcttgcaa
     6781 atctacttct attatcacac gttccaccat attcatcatt tctattatta aatatacttg
     6841 atgaaaaact tcctacaagc ctatcaccat gaatttgaat catatcaaaa cctgcttttt
     6901 ttgcattcaa tgctgttact ttaaataaat ttataatatt tttaatttct tctttgggca
     6961 tatttgttat gtaatctttt actccgtcat tcattatttt ttttatctca tcatgtgaag
     7021 taattcccat cttcatagta tctttaatta aattaacatc ataatctgaa caaaatagtt
     7081 gtgctgatac ctttgcacca gaattgtgta tttcatctac aattttcttg tatttaatga
     7141 ctccatcttc atccgatagg cttatagcta ccttatgaaa actaggtcta atagatacat
     7201 ctcctagagt aatcagagct actcctgact tagcaatatc agaaaacttt ttaatttttt
     7261 cttccaattt aagacccatg cttgtaggtg caaaagatac tctatttttt aattccaaat
     7321 ttccaatttt aattggtttt aataaattac aatacatcct attcttcctc cacagctgtt
     7381 tttatatcct ttaccacatg taaattcttt accagttctt tatattctgt atctgagaac
     7441 tcttttttta tgtggttatc ccactttgaa aatatgtttt ttatatcccc taatacttcc
     7501 tcacccttat ctgttactct caactgaaaa gctctactat cattagggtt ttggattttt
     7561 tctatgtatc catcttgttc taacctagat atagttcttg ttgtatgagc tttatcaact
     7621 tcaaattctg tagaaacatc attcaaagaa caattcctat ttttattaat ataaattaaa
     7681 tagaaatata gaccattcgt aagtttatat ggttttaaac atttttcaca ataaagttta
     7741 aagttttttt gcaagttaca aataatatat gacaaacttt catactgtaa atttttaaaa
     7801 tccatcttaa atttcccttc tataattata atatgtttga ctatatcaac tatattatat
     7861 taaacaatta atatagtcaa gaatatttta ttctctaaat ctatgtttta ttaattcttt
     7921 aaaaaactat tatataaaat aatcatgata aaattagaaa ttggaatttt taatatgcac
     7981 tgtacataaa tatattttat ataaaagttt atattttcaa acaagtaatt tttcgaaaat
     8041 tgtctaaatt cagtaaaaat atggtaatat atacataagc aatataaatc tataaaaagg
     8101 agtgttacat atgatatcta ataaaatgca aactttagtt gcaaatagtt ctgttataag
     8161 agctatgttt gaagaaggaa agaaactttc tgatatttat ggtgaggaaa atgtttttga
     8221 ttttagtata ggaaatccaa gtgttgaacc tccagagact attaaagcag ttataaatga
     8281 tattttaaat gaagaatctc caaatttagt tcatggatat atgaacaact caggatatga
     8341 ggatgtaaga gatgctattg ctgaacacat aaataaaaaa gatggattaa atcttacaag
     8401 agaaaattta attatgactt gtggtgctgc tggtggtcta aatattattt taaaaactct
     8461 tttaaatcct ggtgatgaag ttattgcttt tgcaccgtat tttggtgagt ataaaaatta
     8521 tacagaaaac tatgatggaa aattaataga agttcctaca aatatagaga cttttgaacc
     8581 agatttagat gctctaaaaa atgctattac tccaaaaaca agagctttaa taataaacac
     8641 tccaaataat cctactggtg tcatatattc tgaagaatta ttaaaaaatc ttggagaatt
     8701 attggattca aaacaaaaag aatttaatac aagcatatat ctaatttctg atgagccata
     8761 tagagaaata atttatgatg gtgccaaagt tccttgtgta ctaaaatact atagaaattc
     8821 atttataggg tactcttata gtaaatcatt atctctacct ggtgaacgta taggatatat
     8881 tgttgctaat gggcaaatgg atgattttga tgatgttatg tcttcattaa atgttgcaaa
     8941 tagaatactt ggatttgtaa atgctccttc tctttttcaa agggttattg caagaagttt
     9001 agatgcagaa gttgatgtaa atatttataa aaagaatttt gaccttctat ataatagttt
     9061 aatcgatatg ggatattctt gtgttaaacc taatggtaca ttctatttgt tcccaaaagc
     9121 tccaattgaa gatgataaaa aattctgcaa tgatgcaaaa caatttaatt tattattagt
     9181 accaggttct tcttttggtt gtccaggtca ttttagagta tcatattgtg tatcttatga
     9241 taaagttaaa agttctttac cagcatttga aaaattagcc aaattatata atttaaaata
     9301 actaaatcaa agtaattcaa ataattaact accttagtat agaatactta cattctatat
     9361 taaggtagtt tataatttta tgtactatat tttatacata ccatattatt ccaatatgct
     9421 tgaatattct tatctatagt actaatataa attacaagga ggtgtttgac ttgaaaaaag
     9481 gttatgttta tataatactg actaccttat tttttagttc aatggaaatt agtctaaaaa
     9541 ctgtcactaa tgactttaat cccttacaaa taactttatc aagatttttt gttggcggtt
     9601 tagtcttact accttttgct gtaaaaagat taagagctct tagtctttct attacaaaat
     9661 cagacttaaa atactttgca tttttaggtt ttatgtgtgt agtagtaagt atgtcattgt
     9721 atcaactggc tgttctaaac acaaaggctt ctgtagttgc tgttttgttc agttgtaatc
     9781 cagtctttgt aatgctttta gcttacttaa ttttgaagga aaaaatatat aggcacaatg
     9841 taatttcact tatattagaa gttcttggaa ttatagttat aataaatcca ttgcatacaa
     9901 aactaactct tagtggaata ttcttaacat tatcttctgc tattattttt tcaatgtata
     9961 ctgtatttgg taaaagaaaa accttaaaat ttggtggaat agttgtaact tgctttagct
    10021 ttatatttgg tagtttggaa atgttgatat tggttttact cactaaaatt aattttatcg
    10081 cagatatatt aaataaaaat aaacttcata tatttgcaaa tatccctatt tttagtggat
    10141 ataccttaca caatatgccc attatgattt atgtattcgt atttgttaca ggtgttggtt
    10201 atgcacttta ctttatggca atggaagcta catctactag tcttacatct ttagtattct
    10261 tctttaaacc agtactatct ccaatactag cattattaat acttaaagaa attatcccta
    10321 taaacatggt tataggaatt ttattgatag taattggttc aataatttct attataccta
    10381 cgataattac tcaaatgcat aataaacacg ttgaagcctt gtataaggag tagtaattga
    10441 taatctatca agttatacat aagacaaaat ttattagatt taaacgcaat ataaaagaga
    10501 tgctattata atagcatctc ttaatttata tttattttaa atttattaaa gctctattta
    10561 gctaaatttt gcaaaaagct ataagtttgt ggacaagctg attttaactt actatttgta
    10621 tcttgattta aatagtaata tgcaaatgct tctgcaaaaa attcttctgg atatacacct
    10681 aagtagttta cattacctaa agaacgacct tctttagcaa atatttgttt gaattgtgct
    10741 gatttagata tatcatttaa tactatatgg tctattgcat gtgctgtttc atgtaattct
    10801 aaatttattg catcatgccc tttacctttg ttactaaatc ctattctaag agctactgta
    10861 cttccaccta agcctggaac atcatcccaa gtttttccag taccttccca tcccttagga
    10921 actacacctt ttaaataagc atattctttt tcatctgtta actttccact taataatttt
    10981 atttttaagt tattttgctt taatacattt aaatactttc catctatatt agctaatcta
    11041 tttaccatag cattagcttc gtttttattg taatttccag ttggaaaaac tactatttga
    11101 ctaagtgtgt ctttattttg ttgtatagta gtactatatg catgtgcact tactggaact
    11161 gaacttatta agaatattga tattatagct attaataatt ttttacttgg tctcatatta
    11221 ttccctcctt tgagttaggc cgggagtaat aaatttcaaa ataaaaaaga tacccaagag
    11281 tatctttgta tatacaaaaa gaaattttta ctcttttcgg caactggctg gcatggttta
    11341 ctaaacttta gcccctatag ctttgcgtga ctaggtttcc ctagttttgc ctcatttaat
    11401 tttatatcta tattatagct tatatctttt taattgtcta tatccctttg gaactttttt
    11461 ctaaaaagtt attatttttt tacataaatc ttcaaaaaaa aatatcttct aacaatattt
    11521 tcattattaa atattgtttt agaagatatt ttttaatata acttatattt tttataatgt
    11581 tagggtctaa tttgtatttt tatttcttct taatacgaca agtcctacaa tagctcctat
    11641 aactaaaagt atttctccaa taattgtagt actatcccct gtttttggtg gtactggtgg
    11701 atttaccaaa gtatcatctt tagctttatt atttttttct tctgacactg atggctttac
    11761 cacttctggt attggaataa tctgtttaac aggagtttct atcacctctt ctgatggtgg
    11821 tactggtgga ttcaatatct ctggtattgg aggatttatt atatcttctg acggtggtac
    11881 tggtggattt ataactatag tatcctctgt atcagatgga tttgatggtt tccttggttt
    11941 atctgtgctt ggtggcactg gtggatttac tattggttca tctgtatttg gcggtacagg
    12001 tggatttact ggtggatttt cttgtcttat gttttctata tttccaatat ctactattct
    12061 accaatatct ttattaccaa tttcaacctt aattttatcc ttcagttttt catatccact
    12121 tggagccatc acttctacta aataatatat tcctggtttt tttacactag attgaattat
    12181 accatcttca tcactaacta aatccttaac tactatattt ccaaatgcat cttctaaatt
    12241 gaacttagca cctgaaagta catttttatc taaagcatcc acttttttag cttcaaaagc
    12301 ataaccttgc ttagtagtct ctactcccgg aggacttgaa ccattaatct gagccacatt
    12361 ttgtatagtc tccccaactt ttacatttgt gaagtttgca tcaaatgtaa cccaactttg
    12421 cacaggttcc ccttctttta tctgtttaaa ttcgtattta tttactaatc ttattgtatt
    12481 ttttccatct ccagcttctt ttttaagttc aagattatca gaatatttta tattagatat
    12541 ttttagagat gggtttactt catccaaaag atttacttgt cctgcatcat aaaccccata
    12601 agttgacata ttgattttgt atttaacaat ctggttatca ctactattta aaaccttttt
    12661 atcaacttct ttttttgcgc ttattaatcc agaatttttc ttaaagttta tctcatcatt
    12721 tttatcaatt tcactattat ttgcatcaag gacagctcta tttatataac tatcttcaat
    12781 actaattacc tttaatgtat aagctataaa aaactttgat tctacttctt ctttactgag
    12841 attaattgta aatccagtta taactttatc tacttgccca ctttcatttc ttttttcttc
    12901 tactttatat gaaatattat tggcaatttt ttctttactc caaggagtcc agctcccatt
    12961 cattggaatt tctacaactc taaaatcatg cccatcttct cctgaagtag tcaatctcat
    13021 accttctggt atattatctg ttataacaac attacttatt ggtgatttat catcatttat
    13081 tgaaatctga tagtttatta cttgaccaac ttgagtaata tttgttgctc ctgaatgtcc
    13141 tttagtaaga agataattat ctcctctatc aaatatactt acagtagcat catcttcttg
    13201 tatcttctta ccatcagatt caatcctagc tacattctta tatttattac catgttttgc
    13261 atttttgtca ctgattctag ccttatactt aacagtatac gatttatcta tatttccaaa
    13321 attaactgaa atagaatttt tactctgttc aatattaaaa tcactaactt cttttccatc
    13381 acttgttact acacttacag aaccatttat caatgtcaat ccttcaggaa gctcatcata
    13441 caaaataata tcttttaact cttcctgctt ttcatttact tgtatactgt aatttatatc
    13501 tttattttta actggcataa atacagtagt tgattttttt ccttcaacaa gctttttaag
    13561 tgttccttta gcatctggaa catccgtttt atctccaggt tttatttcta catctatatc
    13621 tccacttcca ctttctattt ttccagtggt ttcaatatgt atttttgcat tagtatcttc
    13681 atcaaccttt ttaacatatg cttccaaacc tattttacct tgcattacac tttggccatt
    13741 aggtaattct ctaaatgtaa gtgtatactc tccattactt tctgttttat caaagcattc
    13801 acttgtataa tctaaattaa ctttattgaa tacatctggc accttaaaag ttattgaatc
    13861 tcctgcttgt attccttttg atgttggagt ataagttaaa ttaaatgata tttttttcat
    13921 tgattccgtt tctattgtat tgttattaat ttttacaaca aatccatagt cttcattaag
    13981 ttcttcttct aaaactttca ataaattttc atcttctaat agattatctt cctctggagt
    14041 tttttctgta tttttattgt ctagtggttt ttcatcttct aaagcttgtt ctgacttttt
    14101 attatctgtt gacttatctt cttctggtat ttgctctggc tttttattat ctattgactt
    14161 ttctccttct ggagttttct ctggcttttt attatctatt ggcttttctc cttctggagt
    14221 tttctctggc tttttattat ctgttgactt atcttcttct gaagtctgtt ctggtttttt
    14281 attatctgtt gaattatctt cctctggggt ctgttctggt tttttattat ctgttgcctt
    14341 atctttctct ggagtctgtt ctggtttttt attgtcgctt tccttctcct ctccagttga
    14401 tgaattagtt gaaccacttt gaatctgact attctctcct aattctgaag cataagatac
    14461 agttggatat attgtagaca ccaccatact taaaatcata attaaactaa ttaataatgc
    14521 ctttttattt cctttcttca tataaatttt ccccctctag gttatctata gtttataatc
    14581 ttccattaat atcgtatata aattaatttt tactaaaaaa ttatataaaa aaagctatga
    14641 aaataaataa atttatattc atagccggtt gcaccactga ctcagtatat ccataaggtg
    14701 cccaataata gaatatactt caacatctct ataatatttc ataaaaacaa ttaaaattgc
    14761 tttatttata ttaaaaatac aattatatac ttctattata ttatgcctct atactattgt
    14821 ctatcttttt tacatttttt accttttatg agattaatta ataattaaat aaaatcctta
    14881 tctacaacaa ttacacaatt atattcagga tttatctcct taactaattt tgttatatct
    14941 tcttttaagt catcctctga catgtctttg gaaaattcgg aaggattaac tactatatca
    15001 aatattaaat tcttcttgct tccttttcca actattctaa aatcatgcat agattttaca
    15061 agactatttt tcttaagtat ttcttcaagt tcttttttgg ctgacataac ttctttatct
    15121 tcaagacata ttgggtccat gtgaattact agatatatat ctaatttttc agatatttct
    15181 ctctctgcag tatctataat ttcatgtatt tccattatat ctatgttgga tggaatttct
    15241 gcatgtatag atgcaataca tctaccaact ccatagttat gaataattaa atcatgtgta
    15301 cctattatat atttataaga taacaatagc tctataatag aatttaccat ttcttcatcc
    15361 ggtgcttctc ctaaaagagg atttatagta tcttttacaa gagagaaacc agcataaagt
    15421 atcactaatg atactacgat accaacatat ccatctatag gaaaattagt aaatctagct
    15481 acaataaatg atataactac acaacttgaa gtaaatacat ctcctaaagc atcaagtgaa
    15541 actgctttta aggctgaaga atcaatttta tttcccacaa atttattaaa acgactcaac
    15601 cagattttaa tcattataga tacaattgaa agtataagtg gtattacttc aaattttaca
    15661 ggaattggat ttactatcct ttctatagat gactttacaa attgaagtcc aaccaacatc
    15721 accataaatg ctactattaa tgctgataaa tactctattc ttccatgacc aaaaggatgt
    15781 tctttgtcag ctggcttact tgctaattta aaacctatca tagttattgc tgaagatgcc
    15841 atatcagaaa gattattaaa tgcatcagcc attatagcta tactagatgt gaacattcct
    15901 atgaatacct ttatcacaaa taaaagtaaa ttggacaata tacctactac accagctaca
    15961 taaccatact tatttctaac atctgtattt tgaacgtttt cgctatctct gataaatgtt
    16021 ttgactagga ttttggaaaa catgaaactt acctccctgc cctttatttt attaacaaat
    16081 tttataatct atatctttat ttatgataac ataatttata tataaaattc ttaaaaatca
    16141 ctctacttca gtaaaatatt attctatata tctatttaga tacaaatttt atatttcgta
    16201 aagtttttat ggcttagtgt ctgtttaata gattctatat aagtttttac aaagattatt
    16261 tattatgata atatcatttt tcccaagtat tacttagaat atgatttttt tgttttgtct
    16321 ttacatattt taaatttata ctatatttat gtttttataa ccttatgata cactataact
    16381 ataagatttt aaacggaaag gaatgaaata aatcatgttt tttatcagtg atatttacac
    16441 aaaatcacct attaaatttg atactccatt gcaaaaatag gtatacaaaa tattacaaaa
    16501 gttagatatt gactttgaac gtgttgacac agatgaagca attacaatgg aagattgtgt
    16561 tcagattaat aaaaaattaa atatgaaaat ggtaaagact ctgtttcttt gcaatagaca
    16621 aaaaactact ttttatctat ttatcatgcc aggtgataaa ccttttaaat caactaattt
    16681 tagcaatgca ttagggatat ccagagtttc ttttgctcct gttgaactca tggaaaaaat
    16741 gttaggaact aaaatcggtg cagcgactat tttcagtgca atacttgata gtgataatgc
    16801 tgtacaaatt gtttttgaca aagatgttgt caatgaagaa tggtatggat gtagtgatgg
    16861 cactactact agttatatga aaattaaaac aaaacaaatt attcgtgatt tcttatcttt
    16921 tgtaggtcat acaccatcta taattgaatt gtaatataaa acaacattaa acaaacacaa
    16981 accgcaaagt cacaatatat atggtacttt gcggtttcat aagaattaat ttttactatt
    17041 aaagttcata gttctactat ttttcattgt tctaagaatt agctttacaa attcatttga
    17101 caataatata gtggatgcaa gtagtattat ttttatccac atatcaaagt ccaaagaaac
    17161 agaattaaag aaactctgga acacttgtgt aaatattatt tgaattatcc ctgtaactac
    17221 tattatttgc aatgccagtt tatttttaaa gaaatttggt attgtactat ttaaaccaaa
    17281 ctctctacaa tttaatgcat taaaaagggc actgaatgca aataaagaaa atataacagt
    17341 accttgttct tctgatgtag ctcccaatat attaaaagct gattgagtaa atacaattgt
    17401 aattataaga atagcattta taataatatt tacaaacata gacctagcta ttattccaga
    17461 atgtctattt attggttttc ttttcaatac ataatctcta acaggttcta atcctaatgc
    17521 tagggctgga ggaccatcca ttattatatt tacccataat aattgtattg tagtaaatgg
    17581 catatcctta ccagtaagtt gagatattat agcaattata aatgctacta tatttacagt
    17641 aagctgaaac tgtataaatc tttgaaagtt ctcatatata cctcttcccc attttattcc
    17701 ctctactata gtactaaagc tatcatcagt caatattata tctgctgcat ttttagatac
    17761 ttctgttcct gaaataccca ttgcaattcc aacatctgct tgactaagtg ctggggcatc
    17821 atttatacca tcacctgtta cagctacaac ttcaccactt ttttgaagtg ctgaaactat
    17881 tctcattttt gtatctggtt tacttcttgc aacaatagat attcctttga tttcttctct
    17941 caattcttta tctgtcaata catctatata tgttgcttca actgcctttt tcccatcatt
    18001 taataatcct aattcatttc caatagccgt tgctgtattt atattatctc ctgtaagcat
    18061 ttttacatct actcctgcat taaatgcttt atcaatggaa tctttgaccc cttctctcaa
    18121 tgggtccact attcctacaa atccactaaa aactaaatta tcttccttca tataacttct
    18181 tgaatttcct attaaattca attcaccttc tgaagtcatt gcaacttctg ttttagaatt
    18241 actcattttt ttataagcaa atcctaatgt tctcatagat ttaatttgta acttcttaat
    18301 ctcatctaaa atactttttt ctacttttgg agttattgga acaatatttt ttccttgttg
    18361 tacataagaa cattttttta ataatacttc tggagcacct tttgaaagta atatatctga
    18421 atcctcttga cgaattaatg ttgacatctt cttttcttct gaactaaatg gtatttgtga
    18481 tatcaaatac gtttgttttc tcatttcatt atagttctta tcattatgat ataaaagtaa
    18541 tgcacactct gttgcgcttc ctatatattt aaatgaatta tcttcttttt ctatatctgc
    18601 agttgaattt actatacagt tttgttcaaa atagctatta ctttgatact ctcctccact
    18661 tatatattta ccatcaacat atgctacctc taccatcatt ttgttttgtg ttaaagtccc
    18721 tgttttgtca gaacatatta cagaaacaga acctatagtt tcacaggctt ctttctttgt
    18781 tactaatgca tttatctttg ccatcttttg cattgttata gctaaggtaa tatttatcat
    18841 agttggcaaa ccttctggaa cagttgcaac tattaatgca atacaaacca tatatgcatt
    18901 tttagcaggt tctaatgatt gtaagaaaga taatacactg cttgtatcta aaattaacat
    18961 accttttctc tgcatctgta taatcataaa catacacaat aaagtagcta ttacgcctga
    19021 tattcctgct attttagcac ccaacttccc taatttaatt tgaagtggag tttgctggtc
    19081 ttcatttgat aaattctgtg ctatcttacc catctctgtc ttatcaccag tatgagtgac
    19141 aaccattatg cccctaccat atgctacaag agtccctcca aataccatat tgacttgctt
    19201 tgcaggtatt gcatcctgtt cgattatttc tgttttagaa taaactactt ccatatctaa
    19261 tacagcatca gcattcttag ctacatcatc agattctcct gttagcatat cttctctaag
    19321 tttcaaattt atagactgta taagtcttcc atctgctggt atcatatccc cagtttctat
    19381 atatacaata tctcctggta ctaaatcatt ttttgatatt ttaattatct tcccatttct
    19441 aagcaccttt acttctatat tttctgttaa ttttgacagg gcatgagctg cttttttaga
    19501 ttttccttca gttattatgc ctatagaaat tccaataaaa atagccccta aaatacctaa
    19561 tgcatcatgt aattctccca caaaagaact tattactgct gctcctatga gaattaatat
    19621 cataggttct gtcaaacttt ctcccaactc atcccaaaat gttctacctt cttttatagt
    19681 aaattcattt aatccatatc taagcttcct ttcttctacc tcattatcat caagtccaat
    19741 ttctggattt gtttttaagt attttaatac ttctttggta ggtttattat aatacctcat
    19801 aactttatcc cccttgttaa ttatctataa ggaattatat gcttatgata gcttgtatat
    19861 tacttttcaa aaaaataagg tgttgattaa tcaacacctt atagtggtta tatattatta
    19921 aattttatgt tacaggcttt ataaattgtg agctatacaa atcaaaatat ttaatcttca
    19981 aaataccctt ctggatataa tgggaactta gatataagtt cttgtgcctc tgctttacat
    20041 tcatctaata cttctttatt atcaatattt tctgctacct tattcattat ccctgctatc
    20101 tgtataactt ctttttcttt cagacctctt tgagatattg atgtaagacc tatacgaaca
    20161 ccactagtta caaatggtga ttgtgggtcg tcaggtataa catttttatt aactgttatt
    20221 cctacatatt caagagcttt ttcaaattgt tttcctgtaa gattcttact tcttaagtca
    20281 accattacta tatgattatc agtacctcca cttacaatac taaaaccatg tgaaatcagt
    20341 tcagaagcta gagtctgagc atttactaca acttgctcca ttatcttttt aaatttatct
    20401 gtacttaaat ataatagtga aaaggctttt gctgcaactg tattaagatg tatagaacct
    20461 aatgttcctg gaaaaacacc tttatcgagt ttctttgcat gttctgcttt acaaagtaca
    20521 ataccacttc ttggtccaca gaaagtcttt gtcgtagatg aagaaacaaa atctgcataa
    20581 ggtacaggac taggtattac tttcgctgcg actaatcctg caacatgtgc catatctacc
    20641 ataaagtaag ctcctacttc ttttgcaacc tttgatattc tttcataatc tattaatctt
    20701 ggatatgaac ttgcccctgc aattataagt tttggtctac attcttttgc ctttgcttca
    20761 agagcatcat aatctatacg tccagtattt gggtctaccc cataaaattc atatttataa
    20821 atatcatgta aaaaattaac tgtgctacca tgtgtcaagt gtccaccttg gtcaagacgc
    20881 atacttaaaa cagtgtcatt tggttttaat attgatgaat atacacaata gttagctgta
    20941 gaacctgaat acggttgtac gtttacatgt tctgctccaa atacttcttt tgcacgtttt
    21001 attgctaggg tttcaagttt atctgcttct tcagaacctg cttgaaaacg agcccctgga
    21061 tagccttctt ctgttttatt tgtaaataca catccactta attcaagtac ttctgttggt
    21121 gctgtacttt cagaagctat catctcaata ttgtgttctt gtctaaccaa ctcatcagct
    21181 acaatcttgt ataactctgg gtctgaaatt tttgttgttt ttaacataat aatcctcctc
    21241 ttaattaaag aatatatttt attagtttaa tcttcattga taaatttatt ataacggtct
    21301 ataaaacgta agatattcct ccaccaggtc ctaatggtat gccaataccc atgaatagta
    21361 acaatattat tatttctatt aatgtaaata ccactgagta tggaatcata ttcgatatga
    21421 cagtacctat acctatatct ttatcatatc ttctggcaaa ggccaatata actggaaaat
    21481 acggaaaaag tggacttatt ggatttgttg aagcatctcc aatacgataa gctatttgag
    21541 ttaatgctgg attaaagtct agtagcataa acatgggaac aaatataggt gctaaaatcg
    21601 cccattttgc agaagcactt cctacaaata aattgataaa tccagatagc aatataaatc
    21661 ctattatcaa tccatagcta ggtatccccg actctgctag taattttgct cctgttattg
    21721 ataaaattgt tcctaagtta ctaagattaa ataaattaat aaactgggat gctataaatg
    21781 ctaggactat atatccaccc atatcactca tactactacc catcatagat actaaatctt
    21841 tgtcactttt tatcttctta cttacttttc catacactaa tcctggagtt aaaaatataa
    21901 tagtgattat aggaactata cctttcatta aaggtgcatt actagatagt atagaaccag
    21961 tctctggatc tttcataaat gcattgtcac ctatacataa ggcaactatc actactacta
    22021 caactaacaa tgataataaa gcgtatttta tacccttatt ttcaagttca ctcaattcct
    22081 gtatatcctt atcatttgtt gaatcattat attttgtaaa acgaggagct ataaattttt
    22141 cagttacaaa tgctcctgca aaagttaaaa ctatcgctga tataaaagca aaataaagat
    22201 tcattgctgg attgccttgg taagatgggt ccatcatttg agctgctggt attgtaaatc
    22261 cagctaacaa tacatctgta gtactaagca taacatttgc tgcaaatccc cctgcaacac
    22321 ctgcaaaagc tgcaaacata cctacaagag gatgtcttcc aattcctaaa aacacaagtg
    22381 ctgcaagtgg tggtaatatt ataaatccta catctgctgc tgtatgtgat aacatacctg
    22441 caaatacgat tgctacagtt acaagttttt gtggaacttt acttataccc tttttcatta
    22501 acacttccat aaatccagat ttctcagcaa cacctgctcc aagcattgta accagtacta
    22561 atcctaaagg agcaaatgac tggaagtttg taactatgct acctaaatat gattgaatct
    22621 gctctttctc tagtagattt actaccttta caacttcttt tgtagaagga tgtatttctt
    22681 ctactcctaa attagatata actgctgaca atattacaac aattatacat agtaataaaa
    22741 atatggttac tgggtctgga agtttatttc ctgctctctc tacaacattt agtgccctca
    22801 tcaataatcc actatctttg tttttttcct gtgaattaat tttcctcaaa ctaatacccc
    22861 ctcataaact ttatctccag aatgctctat cttaaatttt attttttagt ttatccatat
    22921 aatttataac agactgacat agtacatttg tacctaccaa tatagaattt ttatcagctt
    22981 taaatttagg attatgccac tgatatatac aatcttgttc tttattgcct acccctaacc
    23041 agtaaaaaaa tcctggggct ttttccataa atatagaaaa atcttctcct cctgtagaag
    23101 gtattggatc aactatagca tcttctgaat acaaatcaca cacagattta caagctattg
    23161 tgtacatctc tttactattt ataacagctg gtaaatcaaa taaataatct agctttgcag
    23221 ttgcttgata tccacgagct atctcacaaa ctatattttc taaattttct gatattttct
    23281 ttcgtacttc attactaaag cttctacatg tacctgtcat atctaccttt tctgaaatta
    23341 cattatttgc agtccctcca tttatagtac ctattgatat aacagctgat tctaatggac
    23401 ttatgtttct gcttactatg gtttgaatac ccattataat tgcacttgat gctactatag
    23461 ggtctattgt tctgtttggt atacctccgt gacctccaaa tccatttact tctatcttaa
    23521 tagtgtctac tgctgccatt aacccaccta acttaacacc tatttttcca caaggtatat
    23581 ctggatgatt atgaagtcca aatatagcat caacttttgg attttccatt actcctcgtt
    23641 ccactagcat cttcgcacct ttattgactt cttcggctgg ttgaaatata aactttacat
    23701 ttccatgaag actatctcta atatgagaca atacatatgc acatcctaca aggcaagatg
    23761 tgtgtatatc atgcccacat gcatgcatta taccatcata tctggattta tactcaatat
    23821 caacctcttc atatattggc aatgcatcaa tatctcctct cagtgctact gtgggaccat
    23881 catacttccc ttttaataat ccaacaactc ctgtttccat tcctaaatct aatatttcta
    23941 tgtctaaact tactaataaa tcttttatag cttttgtagt cctaaattct ttaaaactta
    24001 attcggggtg catatgaata tctgtaaaaa aatctaaaat atcttcttta tacttttctg
    24061 agattaaaat aagttcatgc atactaacac ctctccaaaa ttttattttt ttatttttta
    24121 ta
//
LOCUS       DACTZW010000066        23942 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.066, whole genome shotgun sequence.
ACCESSION   DACTZW010000066 DACTZW010000000
VERSION     DACTZW010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23942)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23942)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23942
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.066"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            119..826
                     /locus_tag="JAM15_13370"
     CDS             119..826
                     /locus_tag="JAM15_13370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA threonylcarbamoyladenosine dehydratase"
                     /protein_id="HAT6799244.1"
                     /translation="MENNFTTRTSFLVGDDGIEKLNNSNIIVFGVGGVGSFTVEALAR
                     AGVGNITIVDFDDVDITNINRQIPALHSTVGRYKVDVMEERILDINPNINIKKIRSLY
                     NKDTSDEILTERYDYVVDAIDMVSSKIHLIETCEKKGLKIISSMGMGNKLDPTKIVVT
                     DIHKTSTCPLAKVMRKELRDRGIKKLKVVYSTEQPIELKKKVMNGRKVTPGSVSFVPS
                     VGGLIIASVIVNELLGQ"
     gene            complement(968..1804)
                     /locus_tag="JAM15_13375"
     CDS             complement(968..1804)
                     /locus_tag="JAM15_13375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAT6799245.1"
                     /translation="MRNKIFLSILIIISLLIGCDKKSLLSIHIIDVGQGDSILVQTPT
                     NKNILIDGGDEDSENIIISYLRQKRIKTIDIIIATHPDSDHIGSLDNVIKKFNVNSIY
                     MPEQSTDSEAYQNLINSCTDKNLSIQHLYKNDVLNIDNNINIYVLSPSYIQEESNLNS
                     IVFKLTFNDNSFLFMGDAEEENEKEILHSFKLNNINFIKIGHHGSNSSSSLEFIKKIS
                     PDIAAISCGYKNQYGHPHREVINNLKQNHVSIYRTDRIGDIVFYSDGEIIFTKYNYEI
                     DT"
     gene            1992..2897
                     /locus_tag="JAM15_13380"
     CDS             1992..2897
                     /locus_tag="JAM15_13380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2156 domain-containing protein"
                     /protein_id="HAT6799246.1"
                     /translation="MFFKDIELNSKKELDPYFDLVDYEACEYCFSTLYMWQHVYKTGY
                     YIGEDFAVLVGEYEGDSFSILPLAKKDKLPEVVDFVLEYFSKNNKKIYLRGITTEVVE
                     FLKEKYPGRFEYIEERDLFDYIYDAESLRTLAGKKNQKKRNHINYFLKEYAGRYEAKL
                     LDKENFDECLVLMKEWESNKEENNEFDESMDDELIGIKKIFNHYDILKDKVKVFGVYV
                     DGKLEAFSIGELLNPNMALIHIEKANPDIRGLYPFINQQFLVSEFKDVEFVNREEDLG
                     IEGLRKAKLSYHPCRFVEKYSVREA"
     gene            2906..4090
                     /locus_tag="JAM15_13385"
     CDS             2906..4090
                     /locus_tag="JAM15_13385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAT6799247.1"
                     /translation="MEIRYAKEEEIESIKEIWSYCFNDTESFMKYYFNDKYKSENTVV
                     ALDEGKIISSLQLNQYKLLLNSKVYNTSYVVGVSTLPEGRGTGYMSKVMKFTLNELYK
                     KGQLVSILMPIDYRLYRRFGYEHCYDQIEYTINTDDLKNFKSSGKMIKSNLSQIDDLI
                     RIDRAFLNEVNGNVLKDEHYYENLFKEIQSEDGFLYIHEGNEKDGYIVYFLQEDKMFV
                     RELFYKNIDALKSMLKFIYNHNTQCKIVTISTPTIDKIRFILDNPKDSDIKIKPFMMG
                     RVINVKKFIEDIDIEKDINSSFNLLIEDKFIDENNGLFKISIQNKKVSVEQLDKKGAE
                     KPQEDFDIKLDINTLTQLSFSYIDVNEAIFLNDIKDVSEETLETLNCIFSKKNNYINE
                     YI"
     gene            4205..5506
                     /locus_tag="JAM15_13390"
     CDS             4205..5506
                     /locus_tag="JAM15_13390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC/Rec2 family competence protein"
                     /protein_id="HAT6799248.1"
                     /translation="MGVIIIQIRRPLLIILMFVVAISFIITNNTKNDEELNDKIITIQ
                     GVVKGKIEKKRYNQYKVGVFLINDYTKNKNLKIGQKVNITGKFKSLDKMKYDDFDYGR
                     YIKSTGYKGIVYINNYKIIDKTKLYSLIGEIKFYISKTYRYLYKKNSDFINSILLAEV
                     ENLTEEQKEIFTRTGTSHVISISGLHTGILCVIISFLLRGINKLYKLLILSIFITLYC
                     IMVGASPSIIRSIAFVMIFYLSIFIDRKKDGISALSLIGIILIMNNPYVIYNVSFQLS
                     FLATLSILIFYNKINSIIKLSMVSLTISSNILTLPVIYYTFKGIPLLSIIGNLIIVPF
                     VGVIMYLSIASLIVFKVSVVIAKIISFFNSILIESIFFLLEKISNLSFAYINIENPKF
                     YIVVIYYIGVFFYIFYIEGKEIKEQENELQGYYKECKREKL"
     gene            5460..6503
                     /gene="holA"
                     /locus_tag="JAM15_13395"
     CDS             5460..6503
                     /gene="holA"
                     /locus_tag="JAM15_13395"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HAT6799249.1"
                     /translation="MNYKDIIRNVKEKNFEKMYLFYGREYYLIENAIKAFKDSLNEGM
                     LDFNLDIIDGKEIVLNQLISSIETLPFMDDRKIVIIKDFELLKGKKKNFTDSDEKYLI
                     EHLDNIPDTTTIVFVVYGDVDKRKSLVKKIGNNGIVFDCDKLSDMDLFKWIKKSFALN
                     DVIIDNSQIMYFIEQEGYRDKSSEKTLSDLENEINKISSFVGKGNNVTNEVIDKLSQK
                     KVENDIFKLIDYIGEQNASNAMKILNDMIQEGESVLGIFSMIARQFKIIMQVRQLQLD
                     GYSTKLIADKLKMHQFVVGKALKQTKNFSDDIIVEILNYILESDYKIKTGLIRDTLAV
                     EMLVSRYCKREAI"
     gene            complement(6690..6956)
                     /gene="rpsT"
                     /locus_tag="JAM15_13400"
     CDS             complement(6690..6956)
                     /gene="rpsT"
                     /locus_tag="JAM15_13400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002842653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HAT6799250.1"
                     /translation="MANIKSAKKRISVIEKKTALNRVRKSQIKTAIRRFEDAVAAGNR
                     EDAVAKFQYAQKRIYQVASKGTIHKNAAARKVAKLAQKLNGMNA"
     gene            7555..8076
                     /locus_tag="JAM15_13405"
     CDS             7555..8076
                     /locus_tag="JAM15_13405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAT6799251.1"
                     /translation="MDIAKLILNPARLRILQYIRLHGSVRTSDIVKYLNDIPRATVYH
                     HVKILEENNMIEVIKENRVRGTIEKVYALKEYTTSMEGETFVALSTAFYVGLMQEMNE
                     YFSRKEQDHKKDNVFFSSALLYMSDNEYENLLKSIADLLKPYIEQKPKSNLKLRKLSI
                     ISSPPVADNDKTK"
     gene            8110..8886
                     /locus_tag="JAM15_13410"
     CDS             8110..8886
                     /locus_tag="JAM15_13410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAT6799252.1"
                     /translation="MKFHEFGNKNRPHIMLIHGGGNAWWNYLRQAEVLSNNYHVILPT
                     LDGHGEEYETTYISTEDTADKLISYIDENCSGHLFALCGVSLGGQIVMELLSRKPNIT
                     KKAIIDGSICYPRPLMARFCIAGIRFFGGLLFSEKACRFQIAMMPKLLPENMQYPDEI
                     KAYYMTDMPHVRKETFYNMYRTYMMNYILKENVKKTTAQVMYWYGEKEMKCVKKSAKM
                     FQSYVPSCEIYEAKGYNHGYLSLYLPNEWLEIAEPFFQKE"
     gene            9231..10184
                     /locus_tag="JAM15_13415"
     CDS             9231..10184
                     /locus_tag="JAM15_13415"
                     /EC_number="3.4.24.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPR endopeptidase"
                     /protein_id="HAT6799253.1"
                     /translation="MISVRTDLALEASEMCEKSQEGSSIPGVKIETKELENCIVTKVE
                     VIDRQGAEIMNKDIGKYITLESNLMKFDDDESREEMISYLKEELVDIFGQDKNKKTLV
                     IGLGNRNITSDALGPKSVSKTLVTRHLFKNYNKDYDDDFTEVSALSPGVMGVTGIETS
                     EIVKSLVEKVKPDRVVAIDALASRKMERVNSTIQISTAGISPGGGVGNTRKSLTKETL
                     GVDVIAIGVPTVVDAATLTIDVLDMAIDNLIAQSEETESFYEMLKKLKEEEKYHLIKD
                     SLDPYDKNLIVTPKDIDDTIENLSIIISEGLNRSLHPGRLV"
     gene            10202..11221
                     /locus_tag="JAM15_13420"
     CDS             10202..11221
                     /locus_tag="JAM15_13420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein P"
                     /protein_id="HAT6799254.1"
                     /translation="MFKKCIKVVTLTFILVCILPGKSLALNQDDFLKFLVNSSYPEAK
                     VEGNDTENKKNNKNKETSKENKEKSKEENTKSKDASKVDNKKESEKEYIKLYVGKENV
                     PDIESKNSDTTETNTTSSSDYKDDLRVTKENPRILIYHTHGCETYSNSPDGNYHSRDK
                     KNSVMEVGSALTSALDSKGWGVVHTTKYHDYPSYNNSYASSLKTIQSILPKYNSVDIA
                     IDLHRDARDLTNPATKEKDHLKYTTMINGERVSKFFFVVGGKNTNRKQLRALAEDITA
                     FAEKKYPGLVSPIVEKDYARFNQFAVKNHMLVEIGNNATSVEESKATTKYLAEILDEY
                     FKQKN"
     gene            11252..11503
                     /locus_tag="JAM15_13425"
     CDS             11252..11503
                     /locus_tag="JAM15_13425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799255.1"
                     /translation="MSRLEKNIESKSKLRKYKYIMRILFLITMIIGTSVCVFIVDSNA
                     KSMLGMKQYDFPSIKFDITKFDFDIPNFDIHEIIKKFNK"
     gene            11785..13590
                     /gene="lepA"
                     /locus_tag="JAM15_13430"
     CDS             11785..13590
                     /gene="lepA"
                     /locus_tag="JAM15_13430"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002842651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HAT6799256.1"
                     /translation="MDNKQSRTRNFSIIAHIDHGKSTLADRLIQQTGLVSERDMKSQL
                     LDNMDLERERGITIKLQNIRLMYKAKDGNEYYLNLIDTPGHVDFNYEVSRSLAACEGA
                     LLVVDAAQGVEAQTLANVYLAIDQDLEILPIINKIDLPSARPEEVKNEIEDLIGLDSS
                     EAPLISAKTGLNIEDVLEDIVKNVPPPKGDNEAPLKALIFDSYYDAYKGVVAYVRVFE
                     GTVKKGMTIKMMNTNKKFEVTEVGVMAPGQTELSELSAGDVGYIAASIKDIRSCRVGD
                     TITDSNNPTEEPLPGYKKATPMVYCGIYPGEGEKYENVRDALEKLQVNDAALEYEAET
                     SAALGFGFRCGFLGLLHMEIMQERLEREFNLDIITTAPSVIYRVTKMDGEVVMIQNPA
                     NLPEPSEIKMIEEPIVKGDIIVPKDYVGVVMELCQERRGNMLNMEYIDERRVMLHYDL
                     PLNEVVYDFFDALKSRTRGYGSLDYEVKGYVASTLVKLDILINKEQVDALSFIVHETR
                     AFPRGKAMCEKLKGEIPRHQFAIPIQAAVGNKVIARETISALRKDVLAKCYGGDISRK
                     KKLLEKQKEGKKRMRQIGSVEVPQKAFMSVLKLDE"
     gene            13741..15078
                     /locus_tag="JAM15_13435"
     CDS             13741..15078
                     /locus_tag="JAM15_13435"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HAT6799257.1"
                     /translation="MINIEIPKKVDYIIKELETNGYEAYIVGGCVRDCLLERVPNDWD
                     ITTSARPEVVVELFEKTIPTGIQHGTVTVMIEHEPFEVTTYRIDGNYSDGRHPDSIEF
                     TNNIVKDLSRRDFTINSIAYNSKAGLVDPFNGYEDIQNKYIRCVGNPVDRFEEDALRM
                     LRAVRFSAQLNFKIAEGTKQSIHKKADLIKNVSIERIQTEFNKILVSDSSKLNLLKST
                     GLLKFIIPEICELEDVTQHNPYHIYDVQKHTLIATEVIEDELYLKLTMLFHDLGKKVT
                     KTTDKNGVDHFYTHSKESVKIAKKILKRLKYDNYTINKVLILIQYHDYRIEPKRKIIK
                     KLLNKLEDVELFEDLIKVNWADTLAKNPKYAKQKILNLIECEKEFKHIINQKECFNLK
                     DLAINGKDLISIGIKPGKDIGHILNKMLEIVINNPELNEKEILKEKALNIYTF"
     gene            15311..16624
                     /locus_tag="JAM15_13440"
     CDS             15311..16624
                     /locus_tag="JAM15_13440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAT6799258.1"
                     /translation="MHTQLQKTIGLSAALSTVVGMVIGSGVFFKPQAIYTTTNGAPGL
                     GIIAWILGGFITITAGLTATEISAAIPKTGGMMIYIEEIYGEKLGFLTGWMQTVLFFP
                     GTSAALGVIFAQQASELLGMSPNNMTNVLPIAIGVILFLALLNIIGSSLGGKVQTVAT
                     IGKMIPLILIIVFGFIKGQSSEVLNPFVGDSVNASNALGQVLIATLFAYDGWINVGAI
                     SGEMKSPEKDLPRAIVGGLSLVMAVYIIINIAYLWVVPASELAKVTSPATLVATRLFG
                     NIGGKVITVGILISVFGTLNGYLLTGSRIPYTLAEMGTLPASKTLLKVNSGGSPVNSI
                     LLITVLACVYALSGQFNLLTDLTIFSIWVFYVLTFIGVMRLRRQKPDLHRPYKVPLYP
                     IIPIIAILGGLFVIINQILTSTVISLGGIFITLLGLPVYYYMKKR"
     gene            16797..17972
                     /locus_tag="JAM15_13445"
     CDS             16797..17972
                     /locus_tag="JAM15_13445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HAT6799259.1"
                     /translation="MLGLYVHIPFCVKKCKYCDFNSYKMDIDSKKRYIEDLKIEMKLY
                     SNKLYKDNKYKNKECCSLNKNDKITSIFVGGGTPSILTSDEIREVFISIKEMFDIDEN
                     AEITIECNPGTLTLEKLKTMKEIGINRLSIGLQAIQEKHLNFIGRIHTYEEFEKNYKD
                     ALSVGFKNINVDLMYSLPNQTLCDWKETLEKVVHLNPTHISAYSLILEEGTELYNMYE
                     SNKFELIDENVDIEMYEYTINYLKSKGYNQYEISNYSKEGYNCEHNILYWECEYYIGI
                     GAGASGYINENRYNNVESLEDYHLSLVKREKPIQENEILSEKDMIEEKIFMGLRMNKG
                     IKFEDFKKKFGIDFRDKYNKQIEMLLARKLINQNFEGIQLTQKGREISNSVFIEFME"
     gene            18075..19094
                     /gene="hrcA"
                     /locus_tag="JAM15_13450"
     CDS             18075..19094
                     /gene="hrcA"
                     /locus_tag="JAM15_13450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcription repressor HrcA"
                     /protein_id="HAT6799260.1"
                     /translation="MELNERKLNILKAIVKDYIETAEAIGSRTISKRHDLGVSAATIR
                     NEMADLEELGYLIQPHTSAGRVPSEKGYKLYVNSLMSKSELDDNDKILIEQCMNHNIN
                     HIKELIHETSKLLSQLTNYTTVAVTKSLINQSVIKHIQLVAMNDNNILLIVVTDKGDL
                     KKANLTTNVYLDQSKLNLISDNLTRKLLGKSITDLDDNLIAFIKYEISEYSGLIDELL
                     NALNSNMKEEDFSLSLNGATNIFSYPEFNDVLKAKSFLNMLEKKETIADIIKSKGIQK
                     DNLNIIIGSDNDCELAQDCSIVTATYNVDRDLVGRISFIGPTRMDYARIYSIINYMSL
                     LINRK"
     gene            19124..19744
                     /gene="grpE"
                     /locus_tag="JAM15_13455"
     CDS             19124..19744
                     /gene="grpE"
                     /locus_tag="JAM15_13455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HAT6799261.1"
                     /translation="MDKKNEQQEVREENDTSINQESETQVELEEEVVNEECETSSEKT
                     DEKEVDDENVTDINSKLAEKKLQDELDELNDKYQRLQAEYANYRRRTQQEKETIGVFA
                     NEKIITELIPVIDSMERALDACEDKEDTMYKGISLVHKQLIDTLVKFGVEEIEAESKE
                     FDPNLHLAVMQESVDGVEANQIVMVLQKGYKLGTKVVRPSMVKVSC"
     gene            19836..21683
                     /gene="dnaK"
                     /locus_tag="JAM15_13460"
     CDS             19836..21683
                     /gene="dnaK"
                     /locus_tag="JAM15_13460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005365412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HAT6799262.1"
                     /translation="MGKIIGIDLGTTNSCVAVLEGGEAQIIANSEGMRTTPSVVAFTK
                     DGERIVGEPAKRQAVTNADKTITSIKTHMGTDYKVNIDGKSYTPQEISAIILQKLKSD
                     AESYLGQTITEAVITVPAYFTDAQRQATKDAGRIAGLDVKRIINEPTAAALAYGMDKL
                     DQEKKILVFDLGGGTFDVSILEIGDGTFEVLATAGNNRLGGDDFDQIVIDYLADEFKK
                     AEGVDLRNDKMALQRLKEAAEKAKKELSSTMSSNINLPFITATAEGPKHLNIDLSRAK
                     FEELTRGLVEKTMEPTKTALQDAGLSTGDIDDVLLVGGSTRIPAVQEAVKKFIGKEPH
                     KGINPDECVAAGASIQAGVLAGDVKDLLLLDVTPLSLGIETMGNVMTKIIERNTTIPT
                     KKSQIFSTAADNQTAVDIHVLQGERSMAYDNTTLGRFQLTDIPPAQRGIPQIEVTFDI
                     DANGIVNVSAKDLGTGKEQKITITSNTNLSEAEIEQKIKEAEMNAEADKQKKEKIEAF
                     NQAESTIYQTEKTLNELGDKISSGEKEDIEKAIADLKAVKDNQDATAEELKKATDEVM
                     TKFQKVSQEMYQKAAQEQQAAQGAEQAQDNGPKDDNVVDADFKEVDEDK"
     gene            21894..23048
                     /gene="dnaJ"
                     /locus_tag="JAM15_13465"
     CDS             21894..23048
                     /gene="dnaJ"
                     /locus_tag="JAM15_13465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HAT6799263.1"
                     /translation="MSTKRDYYEVLGISKDAEAQEIKKAYRKLAMKYHPDRNPGDKEA
                     EEKFKEINEAYEVLSDDTKRKTYDQFGHDGLNGQGGFGGQGGFGGQGFGGFEDMFGDI
                     FGDMFGGSFGGGRARRRGPQRGADIRQSVTISFEEAAFGKKMSIKVNRSEECEECNGT
                     GAKPGTSKKTCSTCNGTGQVRTVQRTPFGNIASSRPCSACNGTGEVIESPCSKCHGTG
                     NTRKVKTIEVDIPAGIDDGQMIKLSGQGEVGEKGAPRGDLYIVVNVKSHPLFTRDGND
                     IYFEMPITFVQATLGDEIEVPTLDGKVKYSVPEGTQTGTVFRLKEKGIPRIRGNSRGD
                     QYVKVVVEIPKKLNDKQKELLREFAKECGSNVHEKKKTFGQKIEDMFKKK"
BASE COUNT         9610 a         2520 c         4124 g         7688 t
ORIGIN      
        1 cctttttaaa tttattttaa gataatttat ttttaataat atataatgtt ttgtattata
       61 taatgtaaat tttctaatac tattatatat ttagataaaa atctaggagt gtggaaagat
      121 ggaaaataat tttacaacga gaactagttt tctagttgga gatgatggga tagaaaaact
      181 taataattca aatataatag tatttggagt tggaggagtt ggtagtttta ctgttgaagc
      241 tttagcaaga gctggagtag gcaatattac tattgtagat tttgatgatg tagatataac
      301 caatataaat agacaaatac cagccctaca ttcaactgta ggaaggtaca aagttgatgt
      361 catggaagaa agaatattag atataaatcc taatatcaat ataaaaaaaa taagaagtct
      421 ttataataaa gatactagtg acgaaatact aactgaaaga tatgattatg ttgtggatgc
      481 gatagacatg gtaagttcca aaatacatct aattgaaact tgtgaaaaaa aagggttgaa
      541 aataataagt tctatgggta tgggaaataa attagaccca actaaaatag tcgttacaga
      601 tatacacaaa acaagtactt gtcctctagc taaagttatg aggaaagaac ttagggatag
      661 aggtatcaaa aagttaaaag tagtatattc tactgaacaa ccaatagaac ttaagaagaa
      721 agtaatgaat ggtagaaaag taacacctgg tagtgtatca tttgtcccat ctgtaggagg
      781 tttaataatc gcatctgtaa tagtaaatga actattagga caataagttt taaatatttt
      841 aatttataaa ttttatatac aaatttgaag gctagaagca tgaatataaa gcaattttat
      901 attcatactt ttagcctaat tattttatat taccttattt tatgtagttg tagttttatt
      961 ttttagatta tgtatctatt tcataattat attttgtaaa tataatttct ccatcactat
     1021 aaaaaacaat atctcctatt ctatctgttc tataaattga tacatggttt tgttttagat
     1081 tattaataac ctccctatgt ggatgaccat attgattttt atatccacat gatattgcag
     1141 ctatatctgg actaattttt tttataaatt ctaaagatga agaagaatta cttccatgat
     1201 gacctatttt tataaaatta atattattta atttaaaaga atgtaaaatt tctttttcat
     1261 tttcttcttc agcatcaccc ataaataaaa aagaattatc gttaaaagtt aatttgaaaa
     1321 ctatagaatt taaattagat tcttcttgta tatatgatgg acttaataca tatatattta
     1381 tattgttatc tatgtttaaa acatcatttt tatagagatg ctgaatagat aagtttttat
     1441 ccgtacaaga atttattaga ttttgataag cctcactatc agttgattgt tcaggcatat
     1501 atatggagtt tacattaaat ttttttataa cattatcaag acttcctatg tggtctgaat
     1561 ctggatgagt tgctattata atatcaatag tttttattct tttttgtcta agataactaa
     1621 taattatatt ttcgctatct tcatcacctc catcaattaa tatattctta tttgtgggtg
     1681 tttgaactaa aatactatca ccttgtccaa catcaattat atgtatagat agtagagatt
     1741 ttttgtcaca gccgattaaa agtgatatta taataagtat tgataaaaaa attttatttc
     1801 tcaataaaaa atcactccat tcattacatg tttatataaa tttatgatgg gtaatataag
     1861 atatatatga cttattatat tttatatttt aaacaatata aatgaaatta ataccataat
     1921 aaatttggag ttttttatat atacaaaata aaatttttaa aattaagcaa taaaaaaggt
     1981 aggaggattt tatgtttttc aaagatattg aactaaattc aaaaaaagag ttagacccat
     2041 attttgattt agtagattat gaagcttgtg agtactgttt tagtacttta tatatgtggc
     2101 aacatgttta taagacagga tattatatag gtgaagattt tgccgtttta gttggggaat
     2161 acgaaggaga tagtttctca atattaccac ttgctaaaaa agataaactt ccagaagttg
     2221 tagattttgt ccttgaatat ttttctaaaa ataataaaaa aatatactta agaggtatta
     2281 ctactgaagt agtagagttt ttaaaagaaa aatatccagg tagatttgag tatatagaag
     2341 aaagagattt atttgactat atttatgatg cagaaagttt aagaactcta gctggtaaaa
     2401 agaatcaaaa gaagagaaac catataaact atttcttaaa agagtatgca ggtagatatg
     2461 aagctaaatt attagataaa gaaaactttg acgagtgttt agtactaatg aaggaatggg
     2521 aaagtaataa ggaagaaaat aatgaatttg atgaaagtat ggatgacgaa ttaataggta
     2581 tcaaaaagat atttaaccat tatgacatat taaaagataa ggtaaaagtg tttggtgttt
     2641 atgtggatgg aaaattagag gcttttagta taggagaact tttaaatcca aatatggcat
     2701 tgattcatat agaaaaagct aatcccgata taagaggtct gtatccattt ataaatcaac
     2761 aatttttggt aagtgaattt aaggacgttg agtttgtaaa tagagaagaa gatttaggta
     2821 ttgaaggatt aagaaaagct aaactttctt atcatccttg cagatttgtt gaaaagtaca
     2881 gtgttaggga ggcttaatag actatatgga gattaggtat gctaaagaag aagagataga
     2941 aagtataaaa gagatttgga gttattgttt taacgatacg gagagtttta tgaagtacta
     3001 ttttaatgat aaatataaat ctgaaaatac tgtagtagct ttagatgaag gaaaaattat
     3061 ttcttctctt cagctaaatc agtataagtt attactaaat agcaaggtat ataatacatc
     3121 atatgtagta ggagtttcta cacttccaga gggaagagga actggatata tgagcaaagt
     3181 aatgaaattt actttaaacg aattgtataa aaaagggcaa ttagtttcta tattgatgcc
     3241 tattgactat agactttata gaagatttgg atatgagcat tgttacgacc agattgaata
     3301 tactattaac acagatgatt taaaaaattt taagtcaagt ggaaaaatga taaagtctaa
     3361 tttatcacaa attgatgatt tgatacgaat agatagagct tttttaaatg aggttaatgg
     3421 taatgtgtta aaagatgaac attattatga aaacttattt aaagagattc aaagtgaaga
     3481 tggattttta tacattcatg aaggaaatga aaaagatgga tatatagttt attttcttca
     3541 ggaagataaa atgtttgtca gagagttatt ttataaaaat atagatgccc ttaaatcaat
     3601 gcttaaattt atatataatc acaatactca atgtaagata gttactatat ctactcctac
     3661 aatagataag ataagattta tattagacaa ccctaaagat agtgatataa aaataaaacc
     3721 ttttatgatg ggaagagtta taaatgtaaa gaagtttatt gaagatatag atattgagaa
     3781 ggatattaat agctcattta atttattaat agaagacaag tttatagatg aaaataatgg
     3841 tctatttaaa atttctatac agaataagaa ggtatctgta gagcagttag ataaaaaagg
     3901 tgcagaaaag cctcaagaag attttgatat taaattagat ataaatacct taacacagtt
     3961 atcattttct tatatagatg taaatgaagc tattttctta aatgatataa aagatgtttc
     4021 agaagaaaca ctagaaacac ttaattgtat tttttctaaa aaaaataact atataaatga
     4081 atatatatag gtagagtacg ttaaaagatt ttaaaaatct tttgacgtat ttttttgttt
     4141 agataataat ttatcttgtt taaaaatttt ctatttgaaa ataatctaaa taatatactt
     4201 ttatatggga gtgattataa ttcaaataag aagaccttta ttaatcatat taatgtttgt
     4261 ggtagctata tcatttatca ttacaaataa cacaaaaaac gacgaagaac ttaatgataa
     4321 gataataact atacaaggag ttgtcaaagg aaaaattgaa aagaaaagat acaatcagta
     4381 taaggtagga gtttttctaa taaatgatta tacaaaaaat aaaaatttga agattggtca
     4441 gaaagttaat attacaggta aatttaaaag tttagataaa atgaagtatg atgattttga
     4501 ttatggaagg tatataaaaa gtactggata taaaggtata gtgtatataa ataactataa
     4561 aattattgat aaaactaaac tttactcttt aataggggaa ataaagtttt atattagtaa
     4621 aacttatagg tacttatata agaaaaactc agattttata aattctatac tattagcaga
     4681 agttgaaaat ttgactgagg aacaaaaaga aatttttacc agaactggaa ctagtcatgt
     4741 aatatctata tcaggtcttc atacaggaat attatgtgta attatatcct ttctattaag
     4801 aggtataaat aaattgtata aattattaat actgtcgatt tttataactt tatattgtat
     4861 aatggtaggt gcgtctccat ccataattag gtctatagca tttgttatga ttttttattt
     4921 atcaatattt attgatagaa agaaagatgg aatatcggca ttgtctctaa ttgggataat
     4981 tttaattatg aataacccct atgttatata taatgtaagt tttcaattgt cttttttagc
     5041 tacactttct atattaatat tctataataa aataaatagt attataaaat taagtatggt
     5101 atcattgaca atatcatcaa atatattaac tttacctgta atttattata catttaaagg
     5161 tataccattg ctttcaatta taggaaattt aattatagta ccatttgtgg gagtaataat
     5221 gtatttaagt attgcaagtt taatcgtatt taaagtaagt gtagtaatag ctaaaattat
     5281 atcttttttt aatagtatat tgatagaaag catatttttt ttactagaaa aaatcagcaa
     5341 tttaagtttt gcatacatta atatagaaaa tcctaaattt tatattgttg ttatttatta
     5401 cataggagtg tttttttaca tattttacat agaaggaaaa gagataaagg agcaagagaa
     5461 tgaattacaa ggatattata aggaatgtaa aagagaaaaa ctttgaaaaa atgtatcttt
     5521 tttatggaag agagtattat ttaattgaga atgcaataaa agcatttaaa gatagtctaa
     5581 acgaaggaat gcttgatttt aatttagata taatagatgg gaaggaaata gtcttaaatc
     5641 agcttataag ctctatagaa acacttccat ttatggatga tagaaagata gtaataataa
     5701 aagacttcga actattaaaa ggaaagaaaa agaattttac agatagtgat gagaaatact
     5761 taatagagca tttagataat attccagaca ctacaactat agtttttgtt gtatatggag
     5821 atgtagacaa aagaaaatca ttagttaaga aaatagggaa caatggaatt gtttttgatt
     5881 gtgataagct ttctgatatg gatttattta aatggataaa aaaatctttt gctttaaatg
     5941 atgttataat agataattct caaatcatgt attttattga acaagaagga tacagagata
     6001 agagcagtga aaagacatta tctgatttag aaaatgaaat aaataaaata agttcctttg
     6061 ttggtaaagg gaataatgta accaatgagg taattgataa attatctcaa aaaaaagttg
     6121 agaatgatat attcaaatta atcgattata ttggagaaca aaatgcttct aatgcaatga
     6181 aaatattaaa tgatatgata caagaaggcg aatctgtatt aggtatattt tctatgatag
     6241 caagacaatt taaaataatt atgcaagtaa gacagttaca acttgatgga tattcaacaa
     6301 aacttatagc tgataaatta aaaatgcatc aatttgttgt aggaaaagca ttaaagcaaa
     6361 ctaaaaattt ttctgatgat ataattgtgg aaatattaaa ctatatatta gaaagtgatt
     6421 ataaaataaa aacaggtctt ataagagata ctttagcagt tgaaatgtta gttagtagat
     6481 actgtaaaag agaagcaatt taaaaaatct atatattaat aaaaaataaa tagcaagata
     6541 tgttatagtt cagagtagat gtaagctaaa ttaagtttga tatacaatca actataatat
     6601 gtctaactat ttatttttta ttgtataaat ttacaaaata aaaaacccct acataggggt
     6661 tattatatat aagaaatata aactggtaat taagcgttca taccgtttaa tttttgagct
     6721 aatttagcta cttttctagc tgcagcattc ttatgtatag ttcctttaga agctacttgg
     6781 tatattcttt tttgagcgta ttggaactta gcaacagcat cctctctgtt tccagctgca
     6841 acagcatctt cgaatcttct tattgcagtt tttatttgag attttctaac tctatttaaa
     6901 gcagttttct tttcgataac acttattctt ttcttagctg attttatatt tgccaccgtg
     6961 ttcacctccc tgtatttttt tatcatattc atcgtcaaca tattagattt taacagaaat
     7021 aaatctaaaa atcaaggatt attatttata tattttaata atgtttttta ttttgatttt
     7081 ttagactgta gactgtgtat aaataatttg caatatcttg tttttaaatt ggtatatttt
     7141 atgttttaaa tattttgaca tatataaatt aatattttat ttttgtaaca aatattttga
     7201 gataatacaa actattaaca tacattttga tagtatttcc aataattata agaaaataca
     7261 agaaattact catttttgta aatttaatga aaaattataa aaatataaat ttatatactt
     7321 aattaagata atttttccaa taatcaagat aatttttttc attagtatgt atgatagatg
     7381 catcaaacaa tataactaat atgttagaag gttatatgta attaatgtca gtgtttatat
     7441 agaatagcat ttgtagcatt tattatagtt gtaattacta cttatatcat agacttgaat
     7501 agtctaaaaa aatagactat aatattttta tagactaaag aaagggctga taagatggac
     7561 atagcaaaac taattttaaa tcctgcaagg cttcgtatct tacaatatat tcgacttcat
     7621 ggcagtgttc gcacatctga tattgtaaag tatttaaatg atattcctcg tgcaacagtt
     7681 tatcaccatg taaaaatttt agaagagaac aatatgattg aagtaattaa agaaaatcgt
     7741 gtgcgtggta ctattgaaaa ggtttatgca ctaaaggaat atacaacatc tatggaagga
     7801 gagaccttcg ttgcactttc tacagcattt tatgtaggtc tgatgcagga aatgaatgaa
     7861 tactttagca gaaaagagca agaccataaa aaggataatg tatttttctc ttcagcatta
     7921 ctatatatga gtgataatga atatgaaaat cttcttaaaa gtatagctga tttattgaaa
     7981 ccatatatag aacaaaaacc taaatcaaat ctaaaactta gaaaactttc aattatatct
     8041 tctccacctg tagctgataa tgataaaaca aaataacatg catcccattt ttataaaagg
     8101 aggttatata tgaaatttca tgagtttgga aataaaaaca gaccacatat tatgttgatt
     8161 catgggggag ggaatgcatg gtggaactat ttgcgacaag cagaagtttt gtctaacaac
     8221 tatcatgtga tacttcctac attggatggt catggagaag aatatgaaac aacatacatt
     8281 tctacagagg atacagcaga taagttgata tcatatatag atgaaaattg cagtgggcat
     8341 cttttcgctt tgtgtggggt atcacttggt ggtcaaattg tcatggaact tttatctcga
     8401 aaacctaata ttactaaaaa agcaattatt gatggtagta tttgctaccc aagacctctt
     8461 atggcaaggt tttgtattgc tggtattcga ttttttggag gacttttgtt tagtgagaag
     8521 gcttgtcgct ttcaaattgc tatgatgcca aaattgttac ctgaaaatat gcaatatcca
     8581 gatgagataa aagcatatta tatgacagat atgccacatg taagaaaaga aacattttat
     8641 aatatgtatc gtacttacat gatgaactat atacttaagg agaatgttaa aaaaaccaca
     8701 gcacaagtaa tgtactggta tggagaaaaa gaaatgaagt gcgttaaaaa atctgcaaaa
     8761 atgtttcagt cttatgtacc ctcttgtgag atttatgaag ctaagggcta taatcatgga
     8821 tatttatcgc tttaccttcc aaatgaatgg ttggaaattg cggaaccctt tttccaaaag
     8881 gaataaaggt gttaggtgat tattgtataa ttattgctgt ttttttaata tagtaaataa
     8941 atcaggtata aatataaaaa aattatttta gtcaatatat tagtgaaagc ttaataggaa
     9001 aatttataaa tagattaaag gtagcgccta tataaatagt tgctaccttt ttctgtttgt
     9061 aaataaatga tagataagaa agtttactga caaattactg actaaaccca attttcttac
     9121 attgaaagcc ttaattttac ttgttttaaa taaatttaca atttcttgtt ataaaatact
     9181 aaattttgtt aacaattata attagcattt aatttatact ggaggtttat atgattagtg
     9241 taagaacaga tttagcttta gaagctagtg aaatgtgtga aaagtctcaa gaaggaagta
     9301 gtattcctgg tgtaaaaata gaaactaaag aattagaaaa ttgcattgta actaaagttg
     9361 aagtaataga caggcaaggc gcagagataa tgaataaaga tataggaaag tatataactc
     9421 tggaaagtaa tcttatgaag tttgatgatg atgagtcgag agaagaaatg ataagttatt
     9481 taaaagagga gttagtagat atatttggcc aagacaaaaa taaaaaaacc ctggtaattg
     9541 gtcttggaaa tagaaatatt acttctgatg cgttaggacc aaagagtgta tcaaaaacac
     9601 ttgtaactag acatcttttt aaaaattata ataaagacta tgatgatgat ttcactgagg
     9661 tatcagcttt aagcccagga gttatgggtg ttactggaat agaaactagt gaaatagtaa
     9721 agtcattggt tgaaaaagta aaaccagata gagtagtagc aatagacgca ttggcttcaa
     9781 gaaaaatgga aagagtaaac tctactatac agatatcaac agcaggaata tcacctggtg
     9841 gaggtgttgg caatactaga aaatctctaa ctaaagaaac tttaggcgtg gatgttattg
     9901 caataggcgt tccaacggtg gttgatgcag caactcttac aatagatgtc ttagatatgg
     9961 caatagacaa tttaatagct caatcagaag aaacagaaag tttttatgaa atgttgaaaa
    10021 aacttaaaga agaagaaaaa tatcatctaa taaaagattc gttagaccca tatgacaaga
    10081 acttaatagt aacaccaaag gatatagatg atacaatcga aaatctatct ataataataa
    10141 gtgaaggctt aaataggtct ttacatccag gtagattggt ataaaataag gaggagcaat
    10201 tatgtttaaa aaatgcatta aagtagtaac cttgactttt atattagtat gcattttacc
    10261 aggaaaatca ttagctttga atcaggatga ttttttaaag tttttagtaa attcatctta
    10321 tccagaagct aaagtcgaag gaaatgatac agaaaataaa aagaataata aaaataaaga
    10381 aacaagcaaa gaaaataagg aaaaaagtaa agaagaaaac actaaatcta aagatgcaag
    10441 taaagttgat aataaaaaag agagtgaaaa agaatatata aaactttatg ttggtaaaga
    10501 aaatgttcca gatattgagt caaaaaattc agacacaact gaaactaaca caacatctag
    10561 ttcagattat aaggatgatt taagagtaac caaagaaaat ccaagaattt tgatatatca
    10621 tactcatgga tgtgagactt attcaaattc acctgatgga aattatcatt caagagataa
    10681 gaaaaattca gtaatggaag taggaagtgc attaactagt gctttagata gcaaaggatg
    10741 gggtgtagtc catactacta aataccatga ctatccatct tataataact cttatgcaag
    10801 tagcttaaaa acaatacaaa gtatattacc taaatataac tcagtggata tagcgataga
    10861 cttacataga gatgctaggg atttaactaa cccagccact aaggaaaaag accatttaaa
    10921 atatacaact atgataaatg gagagagagt atcaaagttc ttctttgttg taggaggtaa
    10981 aaatacaaat agaaaacaac ttagagcttt agcagaagat ataactgctt ttgctgagaa
    11041 aaagtatcct ggtctagtat ctccaatagt agaaaaagac tatgctagat tcaatcagtt
    11101 tgcagttaag aatcatatgt tagtagaaat agggaataac gcaacaagtg tagaagaatc
    11161 taaggctact acaaagtatt tagccgagat tttggatgaa tattttaaac aaaaaaatta
    11221 gagctttaag ttataattag gagcatgtta aatgagccga ttagaaaaaa atatagaaag
    11281 taaaagtaaa ctaagaaaat acaagtatat tatgagaatc ttatttttga ttactatgat
    11341 tataggtaca tcagtttgtg tatttatagt ggacagtaat gcaaaaagta tgctaggaat
    11401 gaaacaatat gattttccaa gtattaaatt tgatataaca aaatttgatt ttgacatacc
    11461 aaattttgat atacatgaaa tcataaaaaa atttaataag tagtaataag tgaataaggt
    11521 ttattgatta aaataagcct tattttagtt atatattttt aatgtataaa ataaaaattc
    11581 attaactgta ttttatagga tttactttaa gtttacgata ttatataata tttagtgtta
    11641 gacttgataa tccacatata atgtggataa ttttgtttag tgccaattag tttatattca
    11701 aaaattttaa atttggtata taaagagttt ttagataatg taaaataata actataagaa
    11761 taatcaagag gagggaattt taaggtggac aataaacaaa gtagaactag aaattttagt
    11821 ataattgcac atatagacca tggaaagtct accttagctg atagattaat acaacaaact
    11881 gggcttgtta gtgaaagaga catgaaaagt caattacttg acaatatgga ccttgaaaga
    11941 gaaagaggaa tcactataaa gcttcaaaac ataagattaa tgtataaagc gaaggatgga
    12001 aatgaatatt atttaaatct tatagataca cctggacatg tagactttaa ctatgaggta
    12061 tcaagaagtt tagctgcatg tgaaggagca ctattagtag ttgatgcagc tcaaggtgtt
    12121 gaggcacaaa ctttagccaa tgtttatctt gctatagacc aagatttaga aatattacca
    12181 ataataaata aaatagattt accaagtgca agaccagagg aagtaaaaaa tgaaatagaa
    12241 gatttaatag ggcttgattc aagtgaagct cctcttattt cagctaaaac tggtttaaac
    12301 atagaagatg ttttagaaga cattgtaaaa aatgttcctc cacctaaggg agataatgaa
    12361 gctccattaa aggcattaat attcgattct tactatgatg cttacaaagg tgttgtagct
    12421 tatgttagag tatttgaagg aactgttaaa aagggtatga caataaaaat gatgaatacc
    12481 aataaaaagt ttgaggtaac tgaagttggt gttatggctc caggtcaaac tgaacttagt
    12541 gaattatcag caggtgatgt tggttatatt gctgctagta taaaagatat aagaagttgt
    12601 cgtgttggtg atacaataac agattcaaat aatcctacag aagaaccttt accaggatac
    12661 aaaaaagcta ctccaatggt atattgtggt atatatccag gagaaggaga aaagtatgag
    12721 aatgttagag atgctcttga aaagcttcaa gtaaatgatg cagcacttga atatgaagct
    12781 gagacttcag cagcactagg atttggtttt agatgtggtt tcttaggtct tttacatatg
    12841 gagataatgc aagaaagact tgagagagaa tttaaccttg atataattac tacagctcca
    12901 tctgttatat atagagttac aaaaatggat ggagaggttg taatgataca aaatcctgca
    12961 aacttaccag aaccatctga gataaagatg atagaagagc ccatagtaaa aggagatata
    13021 atagttccta aagactatgt tggtgttgtt atggagcttt gccaggaaag acgtggaaat
    13081 atgttaaata tggaatatat agatgagaga agagtaatgc ttcactatga ccttcctctc
    13141 aatgaagttg tttatgattt ctttgatgct ttaaaatcaa gaactagagg ttatggttct
    13201 cttgattatg aggttaaagg ttatgtagca tctacacttg taaaacttga tatattaatc
    13261 aataaagaac aagtggatgc acttagtttt attgtccatg agacacgtgc tttccctaga
    13321 ggaaaggcaa tgtgtgagaa attaaaagga gaaattccaa gacatcagtt tgctatacct
    13381 atacaagctg ctgttggtaa taaggttatt gcaagagaaa caataagtgc tctaagaaaa
    13441 gatgttcttg ctaaatgtta tggtggggat atatctcgta agaagaaact tcttgaaaaa
    13501 caaaaagaag gtaagaagcg tatgagacaa attggttctg ttgaagttcc tcaaaaagca
    13561 tttatgtctg tacttaaact agatgaataa attcttataa atttagataa atatatttaa
    13621 aagctagagt gattttagaa ttatttctaa attaatctag cttttttgtg gtatatttta
    13681 agtaaactca tagagaatat aagtaagaat atattaaaga agaataaaaa ggtgatattt
    13741 atgattaata tagaaattcc taaaaaagta gactatataa ttaaagaatt agaaacgaat
    13801 ggttatgaag cttatatagt tggaggatgc gttagagatt gtttattaga aagagttcca
    13861 aacgattggg atataacaac tagtgctaga ccagaagtgg tagtagaatt atttgaaaaa
    13921 acaattccaa ctggtataca acatgggact gtaacagtta tgattgaaca tgaaccattt
    13981 gaagtgacaa cttatagaat tgatggaaat tatagtgatg gtagacatcc agattcaata
    14041 gaatttacaa ataacatagt taaggacttg tcaagaagag attttactat caattcaatt
    14101 gcatacaact caaaggcagg attagtcgac ccatttaatg gctatgaaga tatacaaaat
    14161 aagtatatac gttgtgttgg aaatccagta gatagatttg aagaagatgc acttagaatg
    14221 cttagagcag ttagattttc agcacaactc aattttaaaa tagctgaagg tactaagcaa
    14281 agtattcata aaaaagcaga tttgataaaa aatgtttcta ttgaaagaat ccagacagag
    14341 tttaataaaa tattagtatc tgattcatct aaattaaact tattaaaatc aacaggtttg
    14401 ttgaaattta taattcctga aatatgtgaa ttagaagatg ttactcaaca caatccatat
    14461 catatctatg atgtacaaaa acatacttta atagctacag aagtaattga agatgaactg
    14521 tatttaaaac ttacaatgtt gtttcatgat ttaggtaaaa aagtaactaa aacaactgat
    14581 aaaaatggcg ttgaccattt ttatactcat agtaaagaat ctgtaaagat tgcaaagaag
    14641 attttgaaaa gacttaagta tgataattat actattaata aagttttaat attaatacaa
    14701 tatcatgatt atagaataga acctaaaagg aagataatta aaaagttatt aaataaactt
    14761 gaagatgttg aattatttga agatttaata aaagttaatt gggctgatac acttgccaaa
    14821 aatccaaagt atgcaaaaca aaagatatta aatcttattg agtgtgaaaa agaatttaaa
    14881 catataataa atcaaaagga gtgctttaat cttaaagatt tagctattaa tggaaaagat
    14941 ttgatatcta taggtataaa accaggtaaa gatataggac atattttaaa taagatgctt
    15001 gaaatagtca taaataatcc agagctaaat gaaaaagaaa tactaaaaga aaaagcatta
    15061 aatatatata cattttagat tcaaatataa aaaatttaat tattttaaaa aacatagaat
    15121 aaaatactta tttagataaa ataaataatt ttttgagaat attttagaag ttacgatttt
    15181 atgattttta aatgcatagg catttactct aggactatag actaatataa aaaaaaactt
    15241 tgggaatact aaaaccataa atttataaaa ttaatatttt atatactgta aaacagtgag
    15301 gagggacagt atgcatactc aactacaaaa gactattggt ctttcagcag ctctttctac
    15361 tgttgtaggt atggttatag gttcgggagt tttttttaag ccacaagcaa tatacactac
    15421 aactaatgga gctccaggtt taggtattat agcgtggatt ttaggtggtt ttataacaat
    15481 aactgctggg cttacagcta cagaaatttc agctgctata ccaaaaactg gtggtatgat
    15541 gatttatatc gaagaaatat atggagaaaa gttaggtttt ttaactggat ggatgcaaac
    15601 tgtattattt ttcccaggta catcagcagc attaggagta atatttgctc aacaagcatc
    15661 tgaactttta ggaatgagcc caaataatat gacaaatgta cttcctatag caattggagt
    15721 tatactattt ttagcattat taaatataat aggttcatcc ttaggaggaa aagttcagac
    15781 agtagccact attggaaaga tgataccttt aattttaata atagtctttg gatttattaa
    15841 aggtcaaagt agtgaagtat taaatccatt tgtaggagat agtgtaaatg catcaaatgc
    15901 acttggacaa gtattaatag ctactttgtt tgcatatgat ggttggataa atgttggagc
    15961 tatatcagga gaaatgaagt ctccagagaa agatttacca agagcaatag ttggtggttt
    16021 atcattagtt atggcagttt atattataat aaatatagct tatctttggg tagtaccagc
    16081 aagtgaatta gcaaaagtta cttccccagc tacattagta gcaacaagat tgtttggaaa
    16141 tataggtgga aaagtaataa ctgtgggtat attaatatca gtatttggga cattgaatgg
    16201 atatttatta acaggttcaa ggatacctta tacattagct gaaatgggaa ctttaccagc
    16261 atctaaaact cttttaaaag taaattctgg aggttctcct gtaaattcaa tactacttat
    16321 aactgtgtta gcctgtgtat atgcattatc tggtcaattt aatcttttga cagacttaac
    16381 tatattttca atatgggtat tttatgtatt gacttttata ggtgttatga ggcttagaag
    16441 acaaaagcca gatttacaca gaccatataa agtcccttta tatccaataa taccaattat
    16501 agctatatta ggtggactgt ttgtaataat aaatcaaata ttgacttcaa cagtcatatc
    16561 tttaggcgga atatttataa cactattagg tttaccagtt tattattata tgaaaaaaag
    16621 ataactactt aatttaagtt agataaattt gggtaaaggt gaaaattaac ttttatccaa
    16681 attttttata ctgttataca ataataagta ttatatatta cttgatgtgt tattttgttt
    16741 gatttataat ttagtaattg atgttttaag ataatttaag aaatgaggaa taaaaaatgc
    16801 taggacttta tgtacatatt ccattttgtg tgaaaaaatg taagtattgt gattttaatt
    16861 cttataaaat ggacatagat tcaaaaaaaa gatatataga agacttaaaa atagaaatga
    16921 aattatatag taataaatta tataaagata ataaatataa aaataaagaa tgctgtagtc
    16981 taaataaaaa tgacaaaata acgagtatat ttgtaggggg aggtacacct agtatactaa
    17041 catctgatga aataagagaa gtatttataa gtataaaaga aatgtttgat atagatgaga
    17101 atgcagaaat aactatagag tgtaatcctg ggacattaac attagaaaaa ttaaaaacta
    17161 tgaaagagat tggcataaat agacttagta tagggctaca agccattcaa gaaaagcatt
    17221 tgaattttat aggaagaata catacttatg aagaatttga gaaaaactat aaagatgcat
    17281 taagtgtagg ttttaaaaat attaatgtag atttaatgta cagtcttcca aatcaaactc
    17341 tatgtgactg gaaggaaact cttgaaaaag ttgtacactt aaatccaaca catatatcag
    17401 cgtattccct tatactagaa gaaggaactg aactatataa tatgtatgaa agtaataaat
    17461 ttgagcttat agatgaaaat gtagatatag aaatgtatga gtatacaata aactacttaa
    17521 agtcaaaagg atataatcaa tatgaaatat caaattactc aaaagaaggc tataattgtg
    17581 agcataatat tttatattgg gaatgtgaat attatatagg gattggagca ggagcttctg
    17641 gctatattaa tgagaacaga tacaataatg tagaatcttt agaagattat catttaagtt
    17701 tggtaaaaag agaaaaacca atacaagaaa atgaaattct ttccgaaaaa gatatgatag
    17761 aagaaaagat atttatgggg cttagaatga ataaaggcat aaaatttgaa gattttaaaa
    17821 aaaaatttgg aatagatttt agagataagt ataataagca aatagaaatg ctattagcta
    17881 gaaagcttat aaatcagaac tttgaaggta tacaattaac tcaaaaagga agagaaatat
    17941 ctaatagtgt atttatagaa tttatggaat aatttttaag gtgttgacaa aataaattta
    18001 taatggtata taatatatat aatcttttta gcactcgaac ttagtgagtg ctaacagcta
    18061 ggaggtataa taatatggaa ttaaatgaaa gaaaattaaa tatcctcaaa gctatagtta
    18121 aagattatat agaaacagct gaagctatag gttctagaac aatatctaaa agacatgatt
    18181 taggtgttag tgctgctacc ataagaaatg aaatggctga ccttgaagaa ttagggtatt
    18241 taattcagcc tcatacttct gcgggtagag ttccatctga aaaaggctat aagttatatg
    18301 taaactctct tatgagtaaa agcgaattgg atgataatga taagattctt attgaacaat
    18361 gtatgaatca taatataaat catataaaag aattgattca tgaaacctct aagctattat
    18421 cgcaactaac aaactataca actgtagcag ttactaagag tttaataaat caaagtgtta
    18481 taaagcacat acagttggtt gctatgaatg acaataatat tttacttata gttgtaacag
    18541 ataaagggga cttaaaaaaa gctaacctta caactaatgt atatttagat caatctaagt
    18601 taaatttgat ttctgataat cttacaagga agcttttagg taaaagtata acagatttgg
    18661 atgataatct aattgctttt attaaatacg aaataagtga gtattctgga cttatagatg
    18721 agcttttaaa tgctttgaac tcaaatatga aagaagaaga tttttctcta tcattaaatg
    18781 gagctactaa catatttagt tatccagaat ttaatgatgt attaaaagca aagtcatttt
    18841 taaatatgtt ggaaaaaaag gaaacaatag ctgacataat taaatcaaag ggaatacaaa
    18901 aagacaatct aaatataata attggtagtg ataatgattg tgaactggca caggattgta
    18961 gtatagttac agcaacttat aatgtagata gagacttggt tgggcgaata agctttatag
    19021 gccctaccag aatggattat gctagaattt actctataat aaattatatg agtttattaa
    19081 ttaatagaaa gtaaagaaat tttaaattgc gaggtgtaaa gtcttggata aaaaaaatga
    19141 gcaacaggaa gtaagagaag aaaatgatac ttctattaac caagaatcgg aaactcaagt
    19201 agagttagaa gaggaagttg ttaatgaaga atgtgaaaca tcaagtgaaa aaactgatga
    19261 aaaagaagtt gatgatgaaa atgtaacaga tataaattct aagttagcag aaaaaaaatt
    19321 gcaggatgag ttggatgaat taaatgataa atatcaaaga cttcaagccg aatatgcaaa
    19381 ctacagaaga agaactcaac aagagaaaga gacaataggc gtatttgcaa atgaaaaaat
    19441 aataactgag ttgataccag ttatagatag tatggaaaga gccttagatg catgtgaaga
    19501 taaggaagat actatgtata agggtataag ccttgtacat aaacaattaa tagacacttt
    19561 ggtaaaattt ggagtagaag aaatagaagc agaatctaag gaatttgacc ctaatctaca
    19621 tctagcagtt atgcaagaaa gtgtagatgg agttgaagca aatcaaatag taatggtact
    19681 tcaaaaagga tataagctag gaactaaagt tgtaagacct tcaatggtta aagtttcttg
    19741 ctaagtataa attaaaggtt aaattattta acctaatata aaatattaaa ataagtaaaa
    19801 cttaattata taattactcg aggaggattt tagtcatggg aaaaataata ggaatagatt
    19861 taggaacaac aaattcatgt gttgcagtgt tagaaggtgg agaagcacaa ataatagcaa
    19921 atagtgaagg tatgagaact actccatcag tagtagcatt tacaaaagat ggtgagagaa
    19981 tagttggaga acctgcaaaa agacaagcag ttacaaatgc agataaaaca ataacttcta
    20041 taaaaactca tatgggaact gattataaag taaatataga tggaaaatca tatactccac
    20101 aagaaatatc agcaataata ttacaaaaat taaaatcaga tgcagaaagt tacttaggac
    20161 aaacaataac agaagcagtt ataacagtac cagcttactt tacagatgct caaagacaag
    20221 caactaaaga tgctggtaga atagcagggc ttgatgttaa gagaataata aatgagccaa
    20281 cagcagcagc tcttgcttat ggtatggata aattagacca agaaaagaaa atattagtat
    20341 ttgacttagg tggaggaact tttgacgtat ctatacttga aataggagat ggaacttttg
    20401 aagttttagc tacagctggt aacaatagat taggtggaga tgactttgac caaatagtaa
    20461 tagattattt agcagatgaa tttaaaaaag ctgaaggtgt agatttaaga aatgataaaa
    20521 tggctcttca aagattaaaa gaagcagcag aaaaggctaa gaaagaatta tcatcaacaa
    20581 tgagttcaaa cataaactta cctttcataa ctgctacagc agaaggacca aaacacttaa
    20641 atatagattt atcaagagct aaatttgaag aattaactag aggtttagtt gaaaaaacta
    20701 tggaaccaac taagacagct ttacaagatg caggactttc tacaggtgat atagatgatg
    20761 tattattagt aggtggttct acaagaatac cagcagtaca agaagctgtt aagaagttta
    20821 taggaaaaga acctcataaa ggtataaacc cagatgagtg tgttgcagca ggtgcttcta
    20881 tacaagctgg agttttagca ggggatgtta aagatttatt attactagat gttactccat
    20941 tatctcttgg tatagaaact atgggtaatg taatgactaa gataatagaa agaaatacta
    21001 caataccaac taagaagtct caaatattct caactgctgc tgataaccaa acagctgttg
    21061 atatacatgt tcttcaaggt gaaagaagta tggcttatga caatacaact ttaggaagat
    21121 tccaattaac agatatacca ccagcacaaa gaggaatacc tcaaatagaa gttacttttg
    21181 atatagatgc aaatggtata gttaatgttt cagctaaaga tttaggtaca ggaaaagagc
    21241 aaaaaataac tataacatca aacactaatt tatcagaagc agaaatagag caaaagataa
    21301 aagaagcaga aatgaatgca gaagctgaca aacaaaagaa agaaaaaata gaagcattca
    21361 atcaagctga atctactata tatcaaactg aaaaaacttt aaatgaactt ggagataaaa
    21421 taagttcagg tgaaaaagag gatatagaaa aagctatagc agacttaaaa gctgtaaaag
    21481 ataatcaaga tgctacagca gaagaactta agaaagctac agatgaagta atgactaagt
    21541 tccaaaaagt atctcaagaa atgtaccaaa aagcagctca agaacaacaa gcggcacaag
    21601 gtgcagaaca agcacaagac aatggaccta aagatgacaa tgtagtagat gctgacttta
    21661 aagaagtaga tgaagataaa taagctatat aatatgtaac actaaatgat aattggaaca
    21721 tatatgattt gtgaaaatca tatagatgtt aaagatatat ggacaatata catcataaag
    21781 aatataatat atcatagatt atataactta aagtagaata taagaattaa tgatagcttg
    21841 tagtttatta ttctacaagc tatcgttttg taaaatgaag gtggtgtcaa tttttgagta
    21901 caaaaaggga ttattatgaa gtcttaggta tcagtaaaga tgcagaagct caagagataa
    21961 aaaaagctta tagaaaatta gcaatgaagt accatccaga tagaaatcct ggagataaag
    22021 aggcggaaga aaaatttaaa gagataaatg aagcttatga agttctatct gatgatacaa
    22081 agagaaaaac ttatgatcag tttggacatg atggactaaa tggtcaaggt ggttttggtg
    22141 gtcaaggagg atttggcggt caaggctttg gtggttttga agatatgttc ggagatatat
    22201 ttggtgacat gtttggagga agcttcggag gtggaagagc aagaagaaga gggcctcaac
    22261 gtggtgcaga tataagacag agtgttacta tatcttttga agaagctgca tttggtaaaa
    22321 agatgtctat aaaagtaaat agaagtgaag agtgtgaaga atgtaatgga actggagcaa
    22381 aaccaggaac atcaaagaaa acttgttcaa cttgtaatgg aactggtcaa gttagaactg
    22441 ttcaaagaac tccatttggt aatatagcaa gttcaagacc atgtagtgct tgtaatggaa
    22501 ctggagaagt gattgaatct ccatgtagta aatgtcatgg aactggaaat acaagaaaag
    22561 ttaagactat agaagtagat atacctgctg gtatagatga tggtcaaatg ataaaacttt
    22621 ctggtcaagg tgaagtagga gaaaaaggtg ctccaagagg agacttatat attgtagtta
    22681 atgttaagtc acatccacta tttactagag atggaaatga tatttatttt gaaatgccaa
    22741 ttacatttgt tcaagcaact ttaggtgatg agatagaagt acctactttg gatggaaaag
    22801 ttaaatatag tgtgccagag gggacacaaa ctggaactgt atttagactt aaagagaaag
    22861 gaatccctag aattagaggt aattcaagag gagaccaata tgttaaggtt gtagttgaaa
    22921 ttcctaaaaa attaaacgat aagcaaaaag aactattgag agaatttgcg aaggagtgtg
    22981 ggtcgaacgt ccacgaaaag aagaaaacct tcggacaaaa gatagaagat atgtttaaga
    23041 aaaagtagtt aaagtagcca atatataatc atatttttga aatcttagtt atttataaga
    23101 ttgtcaaagg agatattatg atttttatat tggctatttt tgtataaaaa ataaatgtgc
    23161 ataaaataaa actgaatata aataattttc tgaaaaatac ttgtcctaaa atatataata
    23221 tgctataata taatcaaata aaagaaaggg gtgattccag tgggaacgga tgtggcactg
    23281 ccaaatgatg aagaaaactt tattgtaata tacaaaataa aattagatac ttttagtgct
    23341 agattaagta ctggaaaaac tcatgagctg ggataattat tgtaattacc tagactcaaa
    23401 cttttagtag taaaatagta atattatata gacaaggtat ctaattttta aatcttttgt
    23461 atgagttaaa atttttataa agggtatatc tgattagaat gtaattaggg aaacctagtt
    23521 gtgaattact tttagtatat acatgtgtaa agaaatatgt atatggtatt ggttattgtg
    23581 ctagatgtgt atgtaaagga atatgtgtct agttgggtat atgtaaagaa atatacttat
    23641 aatctatgaa aaatttttag tataaattgc taaaacattg agattgtttt ttatagaaag
    23701 ttagtttata ccaactaaaa atgtgcttaa gatttgtttg atgtttaatt ataaataagg
    23761 ttgtagataa aaaaataagt aaagacaaag gtttaaaata cttgctttaa atatagtttg
    23821 ttttgaacac ttgccaaatt aaaataatta ataaaataga catcttctca tagtaaaata
    23881 tactgtgaga ggatgttttt gctttgttca taaactttta tgaaaaattt gcatagtgtc
    23941 ac
//
LOCUS       DACTZW010000067        23400 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.067, whole genome shotgun sequence.
ACCESSION   DACTZW010000067 DACTZW010000000
VERSION     DACTZW010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23400
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.067"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            147..1055
                     /locus_tag="JAM15_13470"
     CDS             147..1055
                     /locus_tag="JAM15_13470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HAT6799264.1"
                     /translation="MNPLVINLQKCSIHDGPGIRSTVFFKGCPLECVWCHNPESQTYT
                     KQVLYNEERCSKCEACINICPHKAIYKGETKICLDQDKCEFCETCLDYCVNNAREIVG
                     QEYSVRDLVKEIEKDRIFYEESGGGVTLSGGEVMAQDMDFICGVINMCKSKGIHVAID
                     TCGYAKSENYERVAKCADLFLYDIKLIDEDKHIKFTGKSNDLILKNVKILSELGANIN
                     IRIPLIVGVNVDDENLEVKKMIEFLKPLNIQAVSLLPYHNIGKHKYDKIYKKYEGEEL
                     QRPSEEKLEEIKRLFEASNFNTKIGG"
     gene            1060..3429
                     /locus_tag="JAM15_13475"
     CDS             1060..3429
                     /locus_tag="JAM15_13475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016440066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HAT6799265.1"
                     /translation="MARGTFERTKKLREESINAEPHISIERAVLMTEAYKKYEGSVEI
                     PVLRALSFKHYIENRTLSINDGELIVGEKGDSPNGAPTYPEICCHTMEDLEVMHNRDI
                     INFSVSEEARKIHKEEIIPFWKKRQTRDKIINAMTPEWLAAYEAGMFTEFMEQRAPGH
                     TVCGDTIYKKGFLDLKKDIEARLKELDFLNDLDAYNKKADLEAMAIACDAMVILGKRY
                     AEKARQMAEEETDEAKKKDLLLIAETCDVVPAHKPETYHQAIQMYWFVHIGVTTELNI
                     WDAFTPGRLDQHLNPFYERDVENGILDRDRAQELLECLWVKFNNQPAPPKVGITLKES
                     STYTDFANINTGGINPDGQDGVNEVSYIILDVMDEMKLIQPSSNVQISKKTPQKFLKR
                     ACEISRKGWGQPAFYNTEAIVQELMEAGKTIEDARLGGTSGCVETGCFGKEAYVLTGY
                     MNIPKILELTLNNGYDPISKKQIGIETGDPRNFQSYEELFEAFKKQLHYMIDIKIEGN
                     AVIENICAKHMPCPLMSTIVDDCIEKGKDYQRGGARYNTRYIQGVGIGTITDSLTAIK
                     YNVFDKKKFDMDTLLKALDANFEGYEAILNLVSNKTPKYGNDDDYADEIMQEIFNAYY
                     NEVTGRPTVCGGEYRVDMLPTTCHIYFGEIMGASPNGRLCAKPVSEGISPEKGGDTNG
                     PTAVIKSCAKMDHIKTGGTLLNQRFAPSVVQGEKGLDNMANLVRAYFNMDGHHIQFNV
                     FDKNVLLEAQKNPKDYKDLIVRVAGYSDHFNNLSRTLQDEIIGRTEQTF"
     gene            3754..4557
                     /gene="proC"
                     /locus_tag="JAM15_13480"
     CDS             3754..4557
                     /gene="proC"
                     /locus_tag="JAM15_13480"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002846102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HAT6799266.1"
                     /translation="MKTLGFIGSGNMGSAMIGGIVQSGLVKAEDITVSDLSQVALDKV
                     KEEFGVNTTTDSKVAVTNSDVVIVALKPNICEKALTPLKELIDANKIIVSIAAGKTIE
                     SLESFIGSDKKIVRVMPNTPALVGEGMSALCKNSNVTDEELNMIKALFESFGEAEIVS
                     EYLMDTVTGISGSSPAYVFMFIEAMADAAVLAGMPRQQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPAGTTIEAVKVLEEEGFRAAVIKSIVACIDKSKDMSK"
     gene            5155..7911
                     /locus_tag="JAM15_13485"
     CDS             5155..7911
                     /locus_tag="JAM15_13485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017212699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAT6799267.1"
                     /translation="MRDEILSFVNECVLFNNFDELKKESGIITEDIVKKFNLSRTQSS
                     RLLNDLVKSDNLIKINSRPVIFLPKNKINDVVGPTKKSIYENLDELKNECKLLKQETV
                     FNSIIGYDNSLKEVIEQIKTAVLYPNGGLTIMLTGESGVGKTFLAKIIYKYSVSSNVL
                     EKNSPYNVLNCAQYYNNLELLSSLLFGHVKGAYTGANESRAGLIEQSDGGVLFLDEVH
                     RLNSEGQEKLFTFMDTGTFSRIGENGVIRKARVRLIFATTESLSKFLQTFLRRIPINI
                     YVPNIEERGTIEKRKIVEHFIYEESKVLGLPIEITQITLNTILKIKFKGNIGECKNVI
                     KYACGRAYAKNQRRNGNIFVTLQDLPRNLYIENVDIFQFQSGKSKSIIFSPKQFSIEM
                     SNGRNKRNIIYQSFIKCLDYFDRLEKNEITKEKFSKKSSNLMIRLMDNLVFSNNDENN
                     NVLMELIISIMQDIFRNLEVNNNIKYDGNNVLAFSSYLYLKDESYQLSDEYKALESKL
                     LIYLKKESYKEYSIISKISTLITNRLDMYLNNVDTIIMIIFIKSTIIRMKFNQVNATI
                     IAHGYATASSMANVCNRMLGKNIFTAIDMPIDATIADVSKQMSRYLEGDRIKNGLIVL
                     FDMGSLNLIYEDLKNKINSPMLFIDQISTISVLEVGNLLMQGKNIEEIAEIMDEETKP
                     NIQLYYPQKNKEYAIISSCFTGIGTAIKIQHLLSESLIGIVDVKIIPYDYDSLVSMGD
                     KEPVFEMYDVMAIVGTANPNVNGVDFILLEDIISGKGEDDVFRIFSRVVENEKIKNIN
                     DSIVKNFSLIRVIDSLTILDSKKIIERIEEGINAIENIQKKKLSNDKKISLYVHLSCM
                     IERLVRQTEIEEYTDMDLLIKNHHSEVKLIKNAFSVLEKSYSVQIPISEIGYIYNIIY
                     GLPQ"
     gene            8043..8522
                     /locus_tag="JAM15_13490"
     CDS             8043..8522
                     /locus_tag="JAM15_13490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011968307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAT6799268.1"
                     /translation="MVSLMRIDDRLIHGQVAYGWATSLGINVILVANDEAKNDQMKAM
                     SLNLAKPSNVTLYIRGVEESGEIVEKFASSKKSNVLVLVKNTRDALVVAKNSGGVLKE
                     INVGGLRYEEGKKKLTDLVAVDDDDINNFKEIGDLGIDIELRMLPRDKKKQLSDLIK"
     gene            8538..8960
                     /locus_tag="JAM15_13495"
     CDS             8538..8960
                     /locus_tag="JAM15_13495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HAT6799269.1"
                     /translation="MKKFLIATHGELSRELVDTSKLIIGSLANIEYFCMTKDKSADDA
                     EKEIRSILSNNKDSEEFVVLTDVFGGSVANICTNLLLQGFKFELLTGVNLPMLLSILL
                     LVEEDTKLIVKSGLEEAKNGIVYVNELLENRNKIKNVM"
     gene            9000..9791
                     /locus_tag="JAM15_13500"
     CDS             9000..9791
                     /locus_tag="JAM15_13500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011968308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAT6799270.1"
                     /translation="MLVQATMLAIIAGVGILDGRIFGQSMFDRPIVTGMLVGLVLGDI
                     KSGIMIGAQLELIWMGIAGIGAATPPDVVTGGVLGTAFAILSGNGAEVALAVAVPVAV
                     LAQSLGVLVRIINSYFSQKAVFYAKQADFKKVTIMMWLPVILFFLSTSVPTFLAIMIG
                     ADKVTTLINAIPKVILDGLGVAGTLLPAVGFALLMDMLLSKKMSVFFFIGFLLASYGG
                     LDITAIALFGVCVAFVLNFYINNKENNQNPQLAMNTLTEGEIDFE"
     gene            9784..10584
                     /locus_tag="JAM15_13505"
     CDS             9784..10584
                     /locus_tag="JAM15_13505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017212703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAT6799271.1"
                     /translation="MNKLTKKELRSMFWRSFALQGAFNYERMQNLGYCYSMLPAIKKL
                     YNKKENQAKAIERHLEIFNTTTVVVPAILGITAAMEEENANNPEFDESSISAVKTALM
                     GPLAGIGDSLFWGTFRIIAAGVGVSLAKEGNIFGPLLFLLLYNIPAFALRIFGLKYGY
                     KVGVNSLERIQREGLMEKIMSMATTVGLFVVGGMVATMLSITTPLKFNLNGAEVILQD
                     ILDKIIPNMLPLTFAFLIYYMLKRKVSVTKLTIGTIVTGIALHAIGLL"
     gene            10632..11687
                     /locus_tag="JAM15_13510"
     CDS             10632..11687
                     /locus_tag="JAM15_13510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011968310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAT6799272.1"
                     /translation="MTIQDYMLETPVRMREIISNADSLFNEVKRANLKKIIITGSGTS
                     YHSGVQVQPYLQNLLDIDVVKMYPFMITEDTFKFDNENTLVVGVSQGGSSYSTYNAMK
                     LAEDKGCKIASMAGCKNALIDEISDYILTVNCGEEKSGAKTKGYYCTKLNLMLLGLQI
                     AREKGTISSEKYNEEINKILDAINRFEAVYKLSKQWIERNKEKLVNSKEIRIIGHSDI
                     YGDTLEAALKLLETMRIPVTGYEFEEFIHGIYNAINSDSTIFILDTGKEPRVTKMIDV
                     LSGWTENVFAIGRDVTENDKNLKIDITDNPYYQTFNFIVPIQLICGEIPTLRGVDPSV
                     PKDTRFHMKLGSKKLNK"
     gene            complement(11847..13793)
                     /gene="feoB"
                     /locus_tag="JAM15_13515"
     CDS             complement(11847..13793)
                     /gene="feoB"
                     /locus_tag="JAM15_13515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HAT6799273.1"
                     /translation="MINVALLGNPNVGKTTVFNLLTGSNQYVGNWPGVTIEKKEGFLG
                     KEIKVVDLPGIYAMDTFSNEEKVSKSYLENEDVDVIVNVVDASNLSRNLYLTTQLMQF
                     NKPIVILLNMLDIAESKGVNIDAKKLSEELGVIVVPIIAKKKNGVDRIEEEIKGATQK
                     AFIYQKNFGSETETYKKLESILSRCTKTTYTQKKSISDKIDNIVLNPILAYPIFIGVL
                     FLLFKFTFDWVGGPLQEGFASLIEAYISAPVSDMLSNSSPWFKSLIVDGIIGGVGGTL
                     PFFPLIFTLFFGISLFEDSGYMSRTAFLMDKVMRKVGLSGKAFIPIVMGMGCSSPAIM
                     ATRTLESEKDRRVTALIAPLMTCGAKLPIYALFVAIFFPHNAALVTTSLYLVGIVMAI
                     VVALFLNKTAFKTEAEPFILELPEYRIPTIDALIKNTWNKSKGFLIRVVTVMFAMSVV
                     IWGLSSFNVFGYTEDINVSFLATLGHIISPIFKPLGFDDWRTSVAILSGLGAKEIVVN
                     SLNILYGNLTVVLPTIFNGVTAYTFLIFTALYTPCIAALATMKKEYGNKMMFTSFAYQ
                     FILAWIMAFIVKSIGGVLFMGNSIMEALIGGIIIVLALFILFNKFKSTKNGNVCSGCS
                     ICSGCPSANSCSSKEDSNKKSNTH"
     gene            complement(13811..14029)
                     /locus_tag="JAM15_13520"
     CDS             complement(13811..14029)
                     /locus_tag="JAM15_13520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HAT6799274.1"
                     /translation="MTVYDLKIGEKGFINSIDGDIKLSKRLLALGCINSTEIEVKKVA
                     PLGDPIIIRFRGFDLAIRKSDAKNISLQ"
     gene            14235..14744
                     /locus_tag="JAM15_13525"
     CDS             14235..14744
                     /locus_tag="JAM15_13525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HAT6799275.1"
                     /translation="MKTRKMTFLGLMIGYSLALYVLETYIPNPLIVIFPGAKLGLSNI
                     ITLISLMLLGVKDTVIIVTIRVILSSIFAGPLSYLLFSIGGAYLSLLFMYLASKIKDL
                     SLIGISIIGAIGHNIGQLIVASLIIENILAIGYLPFMLMASLVTGMFVGLVSRYTIPK
                     LKHFYSKFY"
     gene            14822..14983
                     /locus_tag="JAM15_13530"
     CDS             14822..14983
                     /locus_tag="JAM15_13530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="HAT6799276.1"
                     /translation="MANNELEALKNEIEAVREEINTYIEYPEIFQEELVESSKKIDIL
                     INKYMYLSK"
     gene            15134..15799
                     /locus_tag="JAM15_13535"
     CDS             15134..15799
                     /locus_tag="JAM15_13535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HAT6799277.1"
                     /translation="MIDIGSKEIAIRLLLALIIGGIIGLEREKIRQFAGFRTHILIAI
                     GSCIVSITSIQLFFDYNLYTNADPARMPAQVLSGIGFLGAGAILKNKGGVKGLTTAAG
                     MWATACIGIAVGYGYYELAILGGLFVMIALFVLRIINTFLFSQEKNVLILKLSNLDSI
                     PFLYDKFEKNQLIVRNMEIECRNEEYWKVNFFVSYAKRIHLHDVMKEINMIEGVINVD
                     YLD"
     gene            15865..17649
                     /gene="pepF"
                     /locus_tag="JAM15_13540"
     CDS             15865..17649
                     /gene="pepF"
                     /locus_tag="JAM15_13540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HAT6799278.1"
                     /translation="MGTDRSTIEEKYKWKIDKMYSSKEEIEKDISKVKNLIQEVKEYK
                     GKLSESKENLYKVLNISENASRIVQNLYVYTHMKQHEDTRINDNQGRATKTEMLSTDL
                     GVATSYIVPEILAIEENKLSEYLKDEKLSFYTKYIKDILRDKPHTLSEREEEILAATS
                     ELSTIPENVYDMLAYADMEFPEIEDEEGNKVKLSHSNYSLFIKSKNSRVRKDAFEGEF
                     STYEKYKNTFASTLYGGIKSEIFYAKTRKYNSAIEASLFSDDVSLDVYNNLISAIDKS
                     IPNLNKYVELKKKFLGLNEIHMYDLYVPLTDKFDMDIPYDKAQDIILEALKPLGEEYL
                     KVIKSAFDEGWIDVYDNEGKKGGAYSWGSYDSHPYILMSYKNDLNSLFTLIHELGHSV
                     HSHYSRTSQPFLYSDYKIFVAEVASTLNELLLINYLLENSKSKDETIYLLNYYLEQFR
                     TTVHRQTMFAEFEKIVHQRVESGEPLTADEFTNIYYKLNEKYYGKSAIVDKQIGIEWA
                     RIPHFYSNFYVYKYATGFSAASALSQQILSEGSTAVDRYINFLKSGGSEYPLEQLKSA
                     GVDMTKKESIEEALNVFAELVNKLEKEL"
     gene            17901..18743
                     /locus_tag="JAM15_13545"
     CDS             17901..18743
                     /locus_tag="JAM15_13545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAT6799279.1"
                     /translation="MFKKKIGVLLASTMLVGALAVGCGSNTGGSGDSGDSSKVSVSGS
                     TSIGPLMETIGEKFQEKNQGVSVEVQQIGSSGGIKNAIEGTSEIGMSSRDLKDEEKSA
                     GLKETKIAIDGIALITNTANSVKNLTMDQVKGIYTGKITNWKEVGGNDAPIVIVSREE
                     GSGTRDGFQEIVGFDSEELTKDAQISDGSGNIKTTVEGNENAIGYISFGYVDEKVNSL
                     KINDVEATDANVIANKYPISRPFILVNKEDGLSEKGKALIDYILSDEGQALVSEKGFI
                     KVNQ"
     regulatory      18976..19059
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            19638..20315
                     /locus_tag="JAM15_13550"
     CDS             19638..20315
                     /locus_tag="JAM15_13550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6799280.1"
                     /translation="MYNLLVVDDDVDILNINQIYFSNIGFNVYTSETAKDAMDIVERI
                     VLDCIILDISLPDIDGYKMCNDIKEKVNIPIIFLSNYEHEEEKVRGFLAGGDDYITKP
                     YSLKELELRIYARMRQYKNITSVPNVLKFSALVINVNSRKVTFDGESIDLTTMEFEIL
                     LFLAENKEQVFSKIEIYNQVWKMPDIGDQHTVQVHIAQMRKKINSLSREHQYIQTVWG
                     KGYKFVP"
     gene            20387..22402
                     /locus_tag="JAM15_13555"
     CDS             20387..22402
                     /locus_tag="JAM15_13555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HAT6799281.1"
                     /translation="MKKYNILKGTLIVLIVSLLAITGLNLLYKYDNKYTYKSIRASNG
                     ILTIDNDTFTKGKLVFLIDDWEFYNHKIFKPNDFTEQDIKPEYVFIGQYPDFSMRKGN
                     QSPYGNATYRMRIKNEGEDKLLSLELPEIFSASEVWINGEIVSKLGDVGTEKYRPKIK
                     NSVVSFIAKKDTEIIINVSNFSHYYSGLYYPPALGETKDISNMMFYRLLFYSIICFTT
                     FAIAIFSLSVWFLSNKSKLYLYFGCMCVFFAIHVSYPFVHLLGLPLVSFTYAVEDSSY
                     FMVVLCIICINGSISKIEEDKVYRFLILPLGITMSIISIVIPIILLPYDMYFVNIYGK
                     LIDIYKYIVFIYILMSSLVSIYKKTCSEHISSYILVSVNTVFGISILFDAVTSNRFEP
                     IFTGWQTEYCGFIIVILFSLMMINRNRIIIKENEKLTRNLEHEVEVRTNELTTLLNER
                     KKFLADVAHDLKAPVSAIQSFIDLIKVGNIHVDEETRTYLYAINQKSNEVQNRVRSLQ
                     EFTSQDKSIGISEKICLNDFIKEIYENNLPDTQACGVNFETYILEKKIYAKINKEMLT
                     RAFENLIYNALTFTPFDGKIILSMDKEDGFAIIKVSDNGKGIPPENIPKVFDRFFTER
                     DNNEPKGQGLGLYIVKSIIREHGGEIFVDSELGKGTVFTIKLSLCFL"
     gene            22452..23132
                     /locus_tag="JAM15_13560"
     CDS             22452..23132
                     /locus_tag="JAM15_13560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6799282.1"
                     /translation="MQTKILIIDGDKDNCQKLKGFLEEKEISIDLAYNCEEAIGKIFS
                     NKYDLIFLEIILTDGDGWTLCKKIRNVTTCPIVYMTYINEEQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRMNSYVNNNENNTKLEEYNRTSGVIKLEDKIIKLTPTENKLL
                     NFFIENPEKTLTTKEIYEHVWMNEYLEDNYSVVVAVNGLRKKIEKDYKNPQKIITIRG
                     AGYYFNKE"
BASE COUNT         9231 a         2565 c         4085 g         7519 t
ORIGIN      
        1 tttaatatta ctaaaaatat atagacaaaa taataacaaa tatagtatta tgtaattgta
       61 gaaatgcttt tcataggtat attctatgaa gatgaattgc ataaaaatga aaaaatggaa
      121 tggatattat ttaggggtga aaaatcatga atccattagt tataaactta caaaaatgta
      181 gcatacatga tggaccaggg ataagaagta cagtattttt taaagggtgt ccacttgaat
      241 gtgtttggtg tcataatcca gagagtcaaa catatacaaa acaagttttg tataatgaag
      301 aaagatgttc aaaatgtgaa gcatgtataa atatatgccc tcataaggca atttacaaag
      361 gtgaaacaaa aatatgctta gaccaagata agtgtgagtt ttgtgaaact tgcttagact
      421 attgtgtaaa caatgcaaga gagattgttg gtcaagagta ttctgtaaga gacttggtta
      481 aagagataga gaaggataga attttctatg aagaatcggg tggtggagta acactatcag
      541 gtggagaagt aatggctcaa gatatggact tcatttgtgg agtaataaac atgtgcaaat
      601 caaagggaat ccatgtagca attgatacat gtggctatgc aaagtcagaa aattatgaaa
      661 gagttgctaa atgtgcagat ttgtttttat atgatattaa gcttattgat gaggataagc
      721 acataaaatt tacaggaaaa tcaaatgact taatactgaa aaatgttaag attttaagtg
      781 aattaggggc taacataaat ataagaatac cattaattgt aggagtaaat gtagatgatg
      841 aaaatttaga ggttaaaaaa atgatagagt ttttaaagcc tttgaatata caagcagtaa
      901 gtcttcttcc atatcataat attggtaaac acaagtatga taaaatttat aaaaagtatg
      961 aaggagaaga actacaaaga ccatcagaag aaaaattaga ggaaataaaa agactgtttg
     1021 aagcaagtaa tttcaatact aagattggag ggtaataaaa tggcaagagg aacttttgag
     1081 agaactaaaa aattaagaga agaaagtatt aatgcagaac cacacatatc tattgaaaga
     1141 gcagtactta tgacagaagc ttataaaaaa tatgagggaa gtgtagagat tcctgtactt
     1201 cgtgctttat catttaagca ttatattgag aatagaactc ttagcataaa tgatggagaa
     1261 ttaatagtag gtgaaaaagg tgattctcct aatggagcac caacatatcc agaaatttgt
     1321 tgtcacacaa tggaagattt agaagtaatg cacaatagag atataataaa ttttagcgta
     1381 tcagaagaag ctagaaaaat acataaagaa gaaataattc ctttttggaa aaagagacaa
     1441 acaagagata agataataaa tgcaatgaca cctgagtggt tagcagcata tgaagcaggt
     1501 atgtttacag aatttatgga acaaagagcc ccaggacata cagtttgtgg agatacaata
     1561 tataaaaaag gatttttaga tttaaagaaa gacatagaag caagattaaa agagctagat
     1621 tttcttaatg atttagatgc atataataaa aaagcagatt tagaagctat ggcaatagct
     1681 tgtgatgcaa tggttatatt aggtaaaaga tatgctgaga aagcaagaca aatggcagaa
     1741 gaagaaacag atgaagctaa gaaaaaagat ttattactaa ttgctgaaac ttgtgatgtt
     1801 gtaccagctc acaaaccaga aacttatcat caagctatac aaatgtattg gtttgttcat
     1861 ataggggtta ctactgaact taatatatgg gatgctttta ctccaggaag acttgaccaa
     1921 catctaaatc ctttctatga aagagatgta gaaaatggaa tactagatag agatagagca
     1981 caagaattac ttgaatgttt atgggttaaa tttaacaatc agccagcacc accaaaagtt
     2041 ggtataacat taaaagaaag tagcacatat acagattttg caaatataaa cactggtgga
     2101 ataaatccag atggtcaaga tggtgttaat gaagttagtt atataatact tgatgttatg
     2161 gatgaaatga aattgataca acctagttca aatgttcaaa taagtaaaaa gactcctcaa
     2221 aaattcttaa agagagcttg tgaaatatca agaaaaggat ggggtcaacc agcattttat
     2281 aatactgaag caatagttca agagcttatg gaagctggaa aaactataga agatgcaaga
     2341 cttggtggaa ccagtggttg tgttgaaact ggatgttttg gtaaagaagc atatgttcta
     2401 actggatata tgaacattcc aaaaatactt gaattaacat taaataatgg atatgaccca
     2461 attagtaaaa aacaaatagg tattgaaact ggagacccta gaaatttcca atcttatgag
     2521 gaactatttg aagcatttaa aaagcaatta cattatatga ttgacataaa aatagaagga
     2581 aatgctgtga tagaaaatat atgtgcaaaa cacatgcctt gtccacttat gtctacaata
     2641 gttgatgatt gtatagaaaa aggcaaggat taccaaagag gtggagcaag atacaacact
     2701 agatatatac aaggtgttgg tataggaact ataacagata gtttaacagc aataaaatat
     2761 aatgtatttg ataagaaaaa attcgatatg gatacattgc ttaaagcact tgatgctaat
     2821 tttgaaggat atgaagctat acttaattta gtttcaaata agactcctaa atatggaaat
     2881 gatgatgatt atgctgatga aataatgcaa gagatattca atgcatatta caatgaggta
     2941 actggtagac caactgtttg tggtggagaa tacagagtag atatgttacc aacaacttgt
     3001 catatatact ttggagaaat tatgggagca agtccaaatg gtagactttg tgcaaaacca
     3061 gtttcagagg gaatttcacc tgaaaaaggt ggagatacta atggacctac agcagttata
     3121 aaatcttgtg ctaagatgga ccacataaaa actggtggaa cattattaaa tcaaagattt
     3181 gcaccatcag tagttcaagg agaaaaaggg ttagataata tggctaatct agtaagagca
     3241 tactttaata tggatggtca tcatatacaa tttaatgtat ttgataaaaa tgtactgtta
     3301 gaggctcaaa agaatcctaa ggattataaa gacttaatag ttagagttgc aggatatagt
     3361 gaccatttca ataatttaag tagaacacta caagatgaga taataggaag aactgagcaa
     3421 acattctagg tttgcttgta aataaaactt cttactatat aaaatcgtaa ctgatataat
     3481 aaagtataaa tggtttgatt ccatttttaa aattttagat taattatgag ctaactttct
     3541 agataggaag ttagctcgtt aagtttaatg aaaaaatcgt taaatttata tttagtaaat
     3601 catacacata ttagtaagta atacatacaa aagaataatt tattatagtt ataataaggt
     3661 tatattttat aaaaataaga taattttaag cagttaaaat aaagtcaatt tagctacttt
     3721 aaaataaaac taatagaaaa aaggagattt gatatgaaaa ctttaggatt tattggttca
     3781 gggaatatgg gaagtgcaat gataggtggc atagtacagt caggattagt aaaggcagaa
     3841 gatataactg tatcagattt aagccaagtt gccttagata aagtaaaaga agaatttgga
     3901 gtaaatacta caactgattc aaaggtagct gttacaaatt ctgatgtggt aatagtagca
     3961 cttaaaccta atatatgcga aaaggcttta actccactta aagaattaat agatgcaaat
     4021 aaaataatag tatctatagc agcaggtaaa actatagaaa gtctggaaag ttttataggt
     4081 tcagataaaa aaatagtaag agtaatgcct aatactccag cccttgttgg cgaaggaatg
     4141 tcagctcttt gtaaaaatag taatgtaaca gatgaagagt taaatatgat taaggctctg
     4201 tttgaatctt ttggtgaggc agaaatagta tcagaatatt taatggatac agttacaggt
     4261 attagtggtt cttctcctgc atatgtattt atgtttatag aagctatggc agatgcagca
     4321 gtattagctg gaatgccaag acaacaagct tataaatttg catctcaagc agtaatgggg
     4381 tcagctaaga tggttcttga aactggaaaa catccaggtg aattaaaaga tatggtttgt
     4441 tctccagcag gaactactat agaagctgtt aaggtattag aagaagaagg ctttagagca
     4501 gcagttataa aatctattgt tgcttgtata gataagtcta aagatatgag caaataacag
     4561 atgtaattaa gtttactata tggtttcttg aattgttttt ttagtactta tttatatcta
     4621 tacataaatg tatttggtat aagtaaaata agagtaattt actataaaaa ggaatttaat
     4681 gattgagtga gaatttatta cttaaatatt aataattaaa tagatatatt tttaactata
     4741 tttgagatat atcattgtga aaaaataaaa tttataagta ttattgtgag gttataagta
     4801 gatttattta aaaataaatt tatttatagc ctttttaaat ttgaaataat attcataagg
     4861 taataaaagt tacaaatatt ttcttcgcta ataagtttta aaatacctat aatgttttac
     4921 tttttattat aataaataca ataaatatat tcttatataa attctatgtc agatatatgg
     4981 aaagataaga accttgagat tatgttaaaa aatctagatt ttatacttat aaaaagtttg
     5041 attttacaat cttacaaaag agaatcaaga taggaatata attatctttt tcataaatat
     5101 ataaatgata tactaatatt atagtattat tgatatttgt attggaggtt gaacatgagg
     5161 gatgaaattt taagttttgt aaatgaatgt gtattattta acaactttga tgaacttaaa
     5221 aaagaaagtg gcataataac agaagatata gtaaaaaagt ttaatttaag tagaactcaa
     5281 tcaagtagat tattaaatga cttagtaaaa tctgataatc ttataaagat aaacagtaga
     5341 cctgttattt ttttacctaa aaataaaata aatgatgtag taggacctac aaaaaaaagt
     5401 atttatgaaa atttagatga acttaaaaat gagtgtaaat tattaaagca agagactgtg
     5461 tttaatagta tcataggata tgataatagc ttaaaagaag taatcgaaca aataaaaacc
     5521 gctgtacttt atccaaatgg cggacttaca ataatgctga caggtgaaag tggagtagga
     5581 aaaacttttt tagccaagat aatatacaaa tatagtgtaa gcagtaatgt attagaaaaa
     5641 aattctccat acaatgtgtt aaactgtgcg cagtattata ataatttgga gttattgtct
     5701 agtctattat ttgggcatgt aaaaggagca tatactggag caaatgaatc tagagcaggt
     5761 ctaatagaac aatcagatgg tggtgtttta tttttagatg aagtacatag attaaatagt
     5821 gaaggtcagg aaaagttatt tacatttatg gatacaggta ccttttctag aattggagag
     5881 aatggagtaa ttagaaaagc tagggtaaga ttaatatttg caacaacaga aagtctatct
     5941 aaatttttgc aaactttttt aagaagaata cccataaata tttatgttcc caatatagaa
     6001 gaaagaggga ctattgaaaa aagaaagatt gtagaacatt ttatttatga agaaagtaag
     6061 gtacttggct tgcctataga gataactcaa attacattaa atacgatttt aaagataaaa
     6121 ttcaagggga atataggtga atgtaaaaat gtaataaaat atgcatgtgg acgagcttat
     6181 gcaaaaaatc aaagaagaaa tggaaatatt tttgttactc ttcaagacct tcctagaaat
     6241 ctttatatag aaaatgtaga tatatttcaa ttccaaagtg gtaaaagcaa aagcattatc
     6301 ttttctccta aacaatttag tattgaaatg tcaaatggaa gaaataaaag aaatataatc
     6361 tatcaaagtt tcataaaatg tttagactac tttgatagac tagaaaaaaa tgaaataaca
     6421 aaggaaaaat ttagtaaaaa gagttctaat ctaatgatta gactaatgga caatttagtc
     6481 ttttcaaata atgatgaaaa taataacgta cttatggagc ttataatatc gataatgcag
     6541 gatatattta gaaatttaga agttaataac aatataaaat acgatgggaa taatgtattg
     6601 gcattttcgt cttatcttta tttgaaggac gaatcttatc aattatctga tgagtataaa
     6661 gctttagaaa gtaaattact aatatattta aaaaaagaga gttacaaaga atactctata
     6721 ataagtaaaa tatcaacatt aataacgaat agattggata tgtatcttaa taatgtagat
     6781 acaatcataa tgattatatt tattaaatca acaattataa gaatgaaatt taatcaagtt
     6841 aatgcgacta ttatagcaca tggatatgct actgccagta gtatggcgaa tgtatgtaat
     6901 cggatgttgg gtaaaaatat atttacagct attgatatgc ctatagatgc taccattgct
     6961 gatgtatcaa aacaaatgtc tagataccta gaaggagata ggataaagaa tggtttaatt
     7021 gtgttatttg atatgggctc tcttaatctt atctatgaag atttaaagaa taagataaat
     7081 agcccaatgt tatttataga ccaaatatcc actatttctg tactagaagt aggaaattta
     7141 ttaatgcaag gtaaaaacat tgaagagatt gcagaaatta tggatgaaga aactaaacct
     7201 aatatacaat tgtattatcc tcaaaaaaat aaagaatatg ctataatatc atcttgtttt
     7261 acagggatag gtactgctat aaaaatccaa catctacttt ccgaaagttt aattgggata
     7321 gttgatgtca aaataatacc ttatgattat gatagtcttg tttctatggg agataaagaa
     7381 ccagtttttg aaatgtatga tgtgatggct atagtaggaa ctgccaatcc aaatgtgaat
     7441 ggggtagatt ttatattatt agaggatata atatcaggaa aaggagaaga tgatgttttt
     7501 agaatattta gcagagtagt agaaaatgaa aaaataaaga acataaatga ttctattgta
     7561 aagaattttt cattaattag agtaatagat agtctaacta ttttagattc aaaaaagata
     7621 atagagagaa tagaagaagg aattaatgct atagaaaata ttcaaaagaa aaaactttca
     7681 aatgataaaa agatttcttt atatgttcac ttaagttgta tgattgaaag attagttaga
     7741 caaactgaaa ttgaagagta tactgatatg gatttgttaa tcaaaaacca tcatagtgaa
     7801 gtaaaactaa taaaaaatgc atttagtgtg ctagaaaaga gttatagtgt gcaaatacca
     7861 atttcagaga taggatatat ttataatatt atctatggtc taccacagta aaatacaaga
     7921 ttacaaaata agtgaatgaa atttaaaaaa gtatgccagt atttggcata ctttttgctt
     7981 ttatagataa atgagagtat aaacaataaa aattttaata tatgatggag gatttgggga
     8041 aaatggtatc tttgatgaga attgatgaca gattgataca tggtcaggtt gcatatggat
     8101 gggcaacatc actaggtata aatgtaatac tagttgcaaa tgatgaagca aaaaatgacc
     8161 aaatgaaagc tatgtcactg aacttagcga aacctagcaa tgtaacttta tatataaggg
     8221 gggtagagga atctggagaa atagtagaaa aatttgcttc ttcaaagaaa agcaatgtat
     8281 tagtgttagt aaaaaatacc agagatgctt tagttgtagc taaaaattca ggaggagtat
     8341 taaaagaaat aaatgtagga gggttaagat atgaagaagg aaaaaagaaa cttacagatt
     8401 tagttgctgt tgatgatgat gatataaata actttaaaga aataggtgat ttaggaattg
     8461 atatagaact tagaatgtta cctagagaca aaaagaaaca actatcagat ttaataaaat
     8521 aatttaggag aaagagaatg aaaaaatttc taattgcaac acatggagaa ttgtctagag
     8581 aacttgttga cacaagtaaa ttaataattg gttcattagc taatattgag tatttttgta
     8641 tgacaaaaga taaatcagca gatgatgctg agaaagaaat tagaagtata ttatcaaata
     8701 ataaagatag tgaagaattt gttgttttaa cagatgtgtt tggtggaagt gtggcaaata
     8761 tatgtacaaa cttacttttg caagggttca aatttgaatt gttgacagga gtaaatttac
     8821 caatgctttt atctatactc ttattagttg aggaggatac aaaactaata gttaaatcag
     8881 gcttagagga agcaaaaaat ggaattgttt atgtaaatga gttattagaa aatcgaaata
     8941 aaatcaaaaa tgtaatgtaa tttaatgtaa attaaactaa gttaaaatgg aggttcaata
     9001 tgttagtaca agctactatg ttagctatta tagcaggagt tggtatacta gatgggcgta
     9061 tatttggtca atctatgttt gataggccaa tagttacagg tatgttagtt ggattagttt
     9121 taggagacat aaaatcagga attatgattg gtgcacagct tgaattaatt tggatgggaa
     9181 ttgcagggat aggtgcagct actcctccag acgtagtaac aggaggtgta ttgggtacag
     9241 cttttgctat attatcaggt aatggtgcag aagttgcttt agcagtggca gtgccagtag
     9301 cagtattagc acaatctctt ggagtattag ttagaataat aaattcgtac ttttctcaaa
     9361 aggcagtttt ctatgctaaa caggctgatt ttaagaaagt taccataatg atgtggttgc
     9421 cagtaatatt attcttttta agtacatcag ttccaacctt tttagcaatt atgattggtg
     9481 ctgataaagt tacaacattg ataaatgcaa tacctaaagt tatattagac ggattgggtg
     9541 ttgcaggaac attgttgcca gcagtaggtt ttgcattgct tatggatatg ttgctttcaa
     9601 aaaagatgtc tgtatttttc tttatagggt ttttgttagc atcttatggt ggattagata
     9661 taactgctat agctttattt ggagtatgtg tagcatttgt actaaacttt tatatcaata
     9721 acaaagaaaa taatcaaaat cctcaattag caatgaatac tttaacggaa ggagagattg
     9781 actttgaata aattaacaaa aaaagaatta agaagtatgt tttggcgttc atttgctctt
     9841 caaggtgcat ttaattacga aagaatgcaa aacttaggtt attgttattc aatgttacct
     9901 gcaataaaga agctatataa taagaaagaa aatcaagcaa aagcaataga aaggcatttg
     9961 gagattttta atacaacgac agtggtagtt cctgctatat taggtataac agcagctatg
    10021 gaagaagaaa atgctaataa tccagaattt gatgaaagtt caattagtgc tgttaaaaca
    10081 gctcttatgg gacctcttgc aggaattggt gattcattat tctggggaac atttaggatt
    10141 atagcagcag gagtaggagt atcacttgca aaagaaggca atatctttgg accactatta
    10201 ttcttattat tatacaatat accagcattt gcccttagaa tatttggact taagtatggt
    10261 tataaagtag gggtaaattc tcttgaaaga atacaaagag agggacttat ggagaagata
    10321 atgtctatgg ctacaactgt cggtttattc gttgtaggag gaatggttgc aactatgttg
    10381 agtataacta ctcctttgaa atttaactta aatggtgcag aagtaatttt acaagatata
    10441 ctagataaaa taatacctaa tatgttacct ttaacctttg catttttaat atattacatg
    10501 ttgaagagaa aggtaagtgt aacaaaatta actataggca ctatagtaac aggaatcgct
    10561 ttacatgcta taggtttgtt atagaaatta attataattt attgaatata tagataagga
    10621 aggtgtataa aatgacaata caagattata tgttagaaac accagttaga atgagagaaa
    10681 ttatatctaa tgcagatagc ttatttaatg aagttaagag agcaaatcta aaaaagatta
    10741 taataacagg ttcaggtact agctatcact caggagtgca agtgcaacca tatttacaaa
    10801 atttattaga tatagatgtt gtgaaaatgt atccatttat gataactgaa gatacattca
    10861 agtttgataa tgaaaatacc ctagtagtag gtgtatctca aggtgggagt agttattcta
    10921 catacaacgc tatgaagtta gctgaagata agggttgtaa aatagcatct atggcaggtt
    10981 gtaagaatgc tttaatagat gagatttctg attatatatt aacagtaaat tgtggtgaag
    11041 aaaaatctgg agctaaaaca aaaggatatt attgtacaaa gttaaactta atgttattag
    11101 gtcttcaaat agctagagaa aaaggtacaa tatctagtga aaagtacaat gaggaaataa
    11161 ataagatatt agatgcaatt aatagatttg aagcagtgta taagctctct aaacaatgga
    11221 ttgaaagaaa caaagaaaag ttagttaatt ctaaagaaat aagaataata ggtcactctg
    11281 atatatatgg agatacatta gaagcagcat taaaattatt ggaaacaatg agaatacctg
    11341 taactgggta tgagtttgaa gagtttatac acggtatata taatgctata aatagtgatt
    11401 ctactatatt tatactagat acaggaaaag aacctagagt aactaagatg attgatgtac
    11461 tttctggttg gacggaaaat gtatttgcta taggtagaga tgttacagaa aatgataaaa
    11521 atttaaagat tgatatcaca gataatcctt actatcaaac atttaatttt atagtaccta
    11581 tacaactaat atgtggggaa atacctacat taagaggcgt agacccaagt gttccaaaag
    11641 atactaggtt ccacatgaag ttaggtagca agaaactgaa taagtaacaa aaaaagaggt
    11701 tgtctcaaaa tagagataag cctctttttg actgttgaaa tgatgaaaat atatttgatt
    11761 ttatataaaa aagagtgcct catgaactaa aaagttaatt ttgagacacc cacttttatc
    11821 ttattttaaa ctaaaatatt tatatattag tgtgtattac tttttttatt gctgtcttcc
    11881 ttacttgagc aagaattagc acttggacat ccagagcaaa tagaacatcc actacagaca
    11941 tttccgtttt ttgtagactt gaatttatta aacagaataa agagtgcaag gactataatt
    12001 attccaccta tcaaagcttc cattattgaa ttacccataa atagtactcc acctatactt
    12061 ttaactataa aagccattat ccatgctagt ataaattgat atgcaaatga tgtaaacatc
    12121 attttattgc catattcttt tttcatagtc gcaagtgcag ctatacatgg agtatataaa
    12181 gcagtaaata tcaagaatgt atatgcagta actccattaa atattgttgg taagacaaca
    12241 gttagattac catatagtat atttaaagag tttactacga tttcttttgc tccaagacca
    12301 cttaaaatag caactgaagt tctccaatca tcaaaaccaa gaggtttgaa tataggagat
    12361 ataatatgac ctagagtagc caagaagctt acatttatat cttctgtata tccaaaaaca
    12421 ttgaatgaag aaagtcccca aattacgact gacattgcaa acatgacagt aacaactctt
    12481 atcaagaaac cttttgattt attccaagta tttttaataa gtgcatctat agtagggatt
    12541 ctatattctg gtaattctaa tataaatggt tcagcctctg ttttaaaggc tgttttattt
    12601 aagaataatg caactacaat tgccataact atacccacca aatacagtga cgtagttact
    12661 aaagcagcat tatgtggaaa gaatatagct acaaatagtg catatatagg tagctttgct
    12721 ccacaagtca taagtggtgc aataagagct gtaactcttc tatctttttc gctttccaat
    12781 gttctagttg ccattatagc tggagaagaa catcccatac ccataactat aggtataaaa
    12841 gctttaccag atagaccaac ctttctcata actttatcca ttaaaaatgc tgttcttgac
    12901 atgtatccac tatcttcaaa caacgatata ccaaagaata atgtaaatat taaagggaag
    12961 aatggtaaag taccaccaac acctccaatt attccatcaa ctataagtga tttaaaccat
    13021 gggctagagt tagataacat atcactaaca ggtgcagaaa tataagcctc tataagacta
    13081 gcaaatccct cttgtagtgg tcctccgacc cagtcaaagg taaatttaaa taagaggaac
    13141 aatacaccaa taaatatcgg atatgctaat ataggattca agactatatt gtctatctta
    13201 tcactgatag atttcttttg tgtatatgta gtttttgtac atctcgataa aatggattct
    13261 aattttttat atgtttctgt ttcacttcca aagtttttct gatatataaa agctttttgc
    13321 gtagctccct taatctcttc ttctatccta tcaacaccat ttttcttttt tgctataatt
    13381 ggaacaacaa ttactccaag ttcttcactt aattttttgg catctatatt aactccttta
    13441 gattctgcaa tgtctaacat attaagcaat ataactatag gcttgttaaa ttgcataagt
    13501 tgagttgtta agtaaaggtt tcttgataaa ttagaagcat caactacatt tactattaca
    13561 tcaacatctt cattttctaa atatgattta gaaacctttt cttcatttga gaaagtatcc
    13621 attgcatata taccaggtaa atcgacaacc tttatctctt ttccaagaaa tccttctttt
    13681 ttttctatag taacaccagg ccagttacct acatattgat ttgaacctgt aagtagatta
    13741 aaaacagtag ttttaccaac atttgggttt cctaataatg ctacattaat cacgggtagc
    13801 tcctcctcta ttattgtaaa gaaatatttt tagcatcaga ttttctaatc gcaaggtcaa
    13861 agcctctaaa tctaattata attgggtctc caagtggggc aaccttttta acttctattt
    13921 cagtactatt tatacatcca agtgcaagca atcttttaga taatttaata tctccatcta
    13981 tactattaat aaatcctttt tctcctattt ttaaatcgta aacagtcatt attaacacct
    14041 cctaatgaaa ttcattatca ttaaaattgt aacaagtatg atacaaaaag tcaagattta
    14101 tagaggtaat tgcacattga aataactaat atttattcta aatagattaa aaatatttta
    14161 gtctaaatta ggtgttttta tatattttgt attataatgt aagatgatag ataaaatttg
    14221 gaggagttaa cttaatgaaa actagaaaaa tgacattttt aggtcttatg atagggtata
    14281 gtttagcttt atatgtacta gagacatata taccaaatcc tcttatagtt atatttccag
    14341 gggcaaaatt gggtttgagc aatattataa ctttaatttc attaatgttg ttaggtgtca
    14401 aagatactgt tataattgtt actatcaggg taattttgtc atcaatattt gcaggccctt
    14461 tatcatatct actatttagt ataggaggag cttatctgag tcttttattt atgtatttag
    14521 cgagtaaaat aaaagattta tcactaatag ggataagcat tataggtgca atagggcata
    14581 atataggtca attaatagtt gcaagtttaa tcatagaaaa tatacttgct atagggtact
    14641 taccatttat gttaatggca tcattagtaa ctggtatgtt tgtaggctta gtatccaggt
    14701 atacaatacc taaattaaag catttttata gtaagtttta ttgacataat attgacaaaa
    14761 tataatattg tttgataaaa tgtatataaa aatatacaaa tttgtaatag tggtgattat
    14821 tatggcgaac aatgaattag aagcgttaaa aaatgagatt gaagcagtta gggaagagat
    14881 aaatacatac atagaatatc cagaaatatt tcaagaagag ttagtagaat caagtaagaa
    14941 aatagatata ttaataaata aatacatgta cctaagcaaa tagcccacag ttgtgggttt
    15001 ttttgtatca aaaattaaca gatggctata ttttacatat attaataata atattaagat
    15061 ataaaatagt atttctgatg tgtaaattat ctgtaggaca taagttgtaa ttaagtcagg
    15121 agggttttat attatgattg atataggaag taaggagata gcaataaggt tactattagc
    15181 actaataata ggaggaataa taggcttaga gagagaaaaa ataagacagt ttgcaggatt
    15241 taggacacat atactaattg caataggttc ttgtattgtt tcaataactt cgattcaatt
    15301 attctttgat tataatttgt atacaaatgc tgacccagca agaatgcctg ctcaagtatt
    15361 atctggaatt ggttttttag gtgcaggagc aattttaaaa aataaaggtg gagtaaaagg
    15421 gcttactaca gctgctggga tgtgggcaac tgcatgtatt ggtatagcag ttggatatgg
    15481 ttattatgaa ttggcaattc taggtggatt atttgtaatg atagcattat ttgtgcttag
    15541 gataatcaat acgtttttat ttagccaaga aaagaatgta ttgatattaa aattaagcaa
    15601 tttggactct ataccttttt tatatgataa atttgaaaaa aatcaactta tcgtaagaaa
    15661 tatggaaata gaatgtcgta atgaagaata ctggaaggtt aatttttttg tatcttatgc
    15721 taagagaata cacttacacg acgttatgaa agaaataaat atgatagaag gagtaataaa
    15781 tgtagattat ttggactaaa atatatacaa tatattttgt aaagtgaata aaatataaaa
    15841 caaattaaaa tagaggtgta tgatatggga actgatagaa gtacaataga agaaaagtac
    15901 aaatggaaga tagataagat gtactccagt aaagaggaaa ttgaaaaaga cataagtaaa
    15961 gtaaaaaatc ttatccaaga agtaaaagaa tataaaggga agctttctga gagtaaggag
    16021 aacttatata aagtattaaa tatctctgaa aatgcatcta ggattgttca aaatttatat
    16081 gtatatactc atatgaaaca acatgaagat actagaatta atgataatca aggaagagcc
    16141 actaagacag aaatgttatc tactgattta ggtgtggcta cttcttatat agttccagaa
    16201 atactggcga tagaagagaa taagttaagt gaatacttaa aagatgagaa gctatccttt
    16261 tatacaaaat atataaagga tatattgaga gataaaccac atactttgag tgaacgagag
    16321 gaagaaatac ttgcagctac atcagaatta tcgacaattc cagaaaatgt atacgatatg
    16381 ttagcatatg cagatatgga atttcctgag atagaagatg aggaggggaa taaggttaag
    16441 ctttctcatt caaactactc tttatttata aaaagtaaga atagtagagt tagaaaagac
    16501 gcttttgaag gtgaattttc aacatatgag aaatataaaa atacatttgc ctcaacgctt
    16561 tatggtggaa taaaatcaga gatattttac gcaaaaacta gaaagtataa ttcagcaata
    16621 gaagcgtctt tattttcaga tgatgtaagt ttagatgttt acaataatct tatatcagct
    16681 atagataaaa gtattcctaa tctaaataaa tatgttgagc ttaaaaagaa atttttagga
    16741 ttgaatgaaa tacacatgta tgatttgtat gttcctttga cagataaatt tgacatggat
    16801 ataccatatg ataaagcaca ggatatcata ttagaggcac ttaaaccttt aggagaagaa
    16861 tacttgaagg tcataaaaag tgcttttgat gaagggtgga ttgatgtata tgataatgaa
    16921 ggtaaaaaag gaggagctta ttcttgggga agttatgatt cacatcctta tatattaatg
    16981 agctataaaa atgaccttaa ttctctattc actttaattc atgaattagg gcactctgtt
    17041 cacagtcatt attcaagaac aagtcaacca tttttatatt cagactataa gatattcgtt
    17101 gcagaagttg catctacatt aaatgaatta cttcttataa attatttatt agaaaattct
    17161 aagtctaagg atgaaactat atacttatta aattattatt tagaacaatt tagaactaca
    17221 gttcatagac aaactatgtt tgctgaattt gaaaaaattg tacatcaaag ggtagagagt
    17281 ggagaaccac ttactgctga tgaatttact aatatatact acaaattaaa tgaaaagtat
    17341 tacggaaaat ctgcaatagt agataaacaa ataggaatag aatgggcgag aatccctcat
    17401 ttttattcaa atttctatgt atataagtat gccacagggt tttctgctgc aagtgcttta
    17461 agtcaacaga tactttcaga aggaagtaca gcagtagata gatatataaa cttcttaaaa
    17521 agtggagggt cagaataccc actagaacaa ttaaaatctg ctggtgtaga tatgacgaaa
    17581 aaagaatcta tagaggaagc cttgaatgta tttgctgaat tagttaataa actagaaaaa
    17641 gagttatagg atgtgataag ttgatagctt caatgaagac ttctaataat atgagttgta
    17701 ttatgtttat atctgcctaa agtaacttta aaaagttaat ctaattaaga ataaatcata
    17761 taaaattaag tttttacatg tatttaacaa tatttacatt tacttaaccc tgctctaata
    17821 ttcatttaac aaagaatctg tattattaaa atatagaaaa atgacaacaa aaaattaaaa
    17881 tataagcggg ggtaagtaaa atgtttaaaa agaaaatagg cgttctttta gctagtacaa
    17941 tgttagttgg agctttagca gtaggatgtg gctctaacac aggaggttca ggagattcag
    18001 gagattcaag caaagtttct gtttcaggtt caacttcaat aggtcctctt atggaaacta
    18061 tcggagaaaa gtttcaagaa aaaaatcaag gtgttagtgt agaagtacaa cagattggtt
    18121 cttctggagg tataaaaaat gccatagaag gaacatctga aataggaatg agttcaagag
    18181 atttaaaaga tgaagaaaaa agtgctggat taaaggaaac taaaatagca atagatggta
    18241 tagcattgat aactaatact gcaaactcag taaaaaacct gacaatggac caagttaaag
    18301 gtatatatac aggaaagatt actaactgga aagaagtagg aggaaatgat gcaccaatag
    18361 taatagtatc aagagaagaa ggttcaggaa ctagagatgg attccaagaa attgtagggt
    18421 ttgattcaga agaactaact aaagatgcac aaataagtga tggttcagga aatataaaaa
    18481 ctacagttga aggaaatgaa aatgctatag gatatatatc attcggatat gttgatgaga
    18541 aagtaaatag tttaaaaata aatgatgttg aagcaactga tgcaaatgta atagctaata
    18601 aatatccaat atcaagacca tttatattag ttaataaaga agatggtttg tcagaaaaag
    18661 ggaaagcttt aatagattat atattaagtg atgaaggaca agcacttgtt tcagaaaaag
    18721 gatttattaa agttaatcaa taacatgaat tataatataa agtaaacata taataccctg
    18781 tgagataagc tcataaaaat gatgctttaa cttgcagggt attgtctatt attgaatgta
    18841 gaaatataaa tatctttaga taaaataggt attttagtat cttatatcta aaaatatgga
    18901 aatattgaca aaataatatt acaatgttag aataaaaaag aaatttatga aaatatataa
    18961 aagattttta ataaaaatat tttagaaact gagaagtata tcttattatt gggcatctgg
    19021 agatatatgg agttagtggt gcaaccggct atgaatataa tttttatatt gcatagtctt
    19081 tttttgtttt aaaattaaca aaaatattgc aaaatttgaa aataagagta ttagtcgtta
    19141 agatttttat tgataggtga aattttagct tttaaagtag ccatttgttg gaaaagggaa
    19201 attttttaaa aagtataata ctattataat aagaaaataa agtttttata aacattgaga
    19261 tgcagaatat aaaccttttg taacaatata tttaccaaaa taatacaatt tattttatat
    19321 tataaccata taaatcatat aaatcaatac tcaaactagc caatagacaa gtttctagaa
    19381 aaataataaa ttttaagtga aaatgacttt aagctccatt ctccaacaat cggagacttt
    19441 aattagtatt taatgatgaa tcttaatgtt caatacaata ttcaagaatt attcaaaaat
    19501 acttaagtat tatagtctag tttgtaaaga tattataaaa taataatact agttatatat
    19561 gaaaataaaa cattataact tgtaataatt ataaaacttg agattatgat taaaatacct
    19621 ttgaatggag tggtgtaatg tataatttac tggttgtaga tgatgatgtt gatattttaa
    19681 acataaatca aatttatttt tctaatatag gttttaatgt atatacatca gagactgcta
    19741 aagatgctat ggatatagta gagcgtatag ttttagactg tataattttg gatatttcat
    19801 tgccagatat agatggatat aaaatgtgca atgatataaa agaaaaggtt aacataccta
    19861 taatattttt atctaattat gagcatgaag aagaaaaagt tcggggattt ttagctgggg
    19921 gggatgatta tataacaaaa ccttatagtt taaaagaact tgaacttaga atatatgctc
    19981 gtatgaggca gtacaaaaat attacatcag ttcctaatgt gttaaagttt tcagcgttag
    20041 taataaatgt aaattcaaga aaagtaactt ttgatggaga aagtatagat ttaactacta
    20101 tggaatttga aatattattg tttctagctg aaaacaaaga acaagtattt tcgaagatag
    20161 agatatataa ccaagtttgg aaaatgcctg atattggaga tcaacataca gtgcaggttc
    20221 atattgcaca gatgagaaaa aaaattaatt ctttaagcag ggagcatcaa tacattcaaa
    20281 ccgtatgggg aaaaggatat aagtttgtac cataagtgag atactgtaat taataaatag
    20341 ttcttgtttt atttaatact actatgaaag agatgtggtt gatgcaatga aaaagtataa
    20401 tatactaaaa ggaactctca ttgtattgat agtctctctg ttggcaataa caggattaaa
    20461 tcttctgtat aaatatgata ataaatatac atataagtct attagagcaa gtaatggaat
    20521 tttaactata gataatgata ctttcactaa aggtaaactt gtctttttga tagatgactg
    20581 ggagttttat aatcataaaa tatttaaacc gaatgatttt acagagcaag atataaaacc
    20641 agaatatgtt tttataggtc aatatccaga tttttctatg agaaaaggga atcagtcacc
    20701 atatgggaat gctacttatc gtatgagaat aaaaaatgaa ggtgaggata agctactaag
    20761 tttagagctt cctgagattt tttccgcaag tgaagtatgg ataaatggag aaatagtttc
    20821 taaattagga gatgtaggaa cagaaaaata tagacccaaa attaaaaatt cagtagtaag
    20881 ttttattgca aagaaagata cagaaattat aatcaatgta tcgaattttt cacattatta
    20941 tagtggtttg tattatccgc ctgcattagg agaaacaaag gacataagta atatgatgtt
    21001 ttatcgatta cttttttata gtataatttg cttcacaact tttgcaatag ctatattttc
    21061 gttgtctgta tggtttcttt caaacaaaag taaactttac ttatattttg gatgtatgtg
    21121 tgttttcttt gccatccatg tatcctatcc ctttgtacat ttgttaggac tgcctttggt
    21181 aagctttaca tatgcggttg aagattcgtc ctattttatg gtagttttat gtattatttg
    21241 tataaatgga agtatatcca aaatagaaga agataaagtg tatagatttt taattttacc
    21301 attaggaatt acaatgagta tcatatctat agtgatacca attattcttc ttccatatga
    21361 tatgtacttt gtcaacatat atgggaaatt aatagacata tataaatata ttgtatttat
    21421 atatatatta atgtcttcgc tggtttcaat atataaaaag acatgctctg agcatataag
    21481 ttcttatatt ttagtttcag taaacactgt ttttggaatt agcatattat ttgatgcagt
    21541 tactagtaat agatttgagc ctatatttac agggtggcaa acagaatatt gtggatttat
    21601 aattgttatt ttattttctc ttatgatgat aaacaggaat agaataataa taaaagagaa
    21661 tgaaaaactt acaaggaatc ttgaacatga agttgaagtg agaactaatg aacttacaac
    21721 attgttaaat gaacgtaaaa aattcttggc agatgtggca catgatttaa aggcacctgt
    21781 ttcagctata caatcattta tagacttgat aaaggttggt aatattcatg tagatgaaga
    21841 gacaagaacc tatctttatg ctataaatca aaagtcaaat gaagtacaaa atagagtacg
    21901 tagtttgcaa gaatttacat cacaagataa aagcattggt attagtgaaa aaatatgtct
    21961 aaatgatttt attaaagaga tatatgaaaa taacttgcca gatacacaag catgtggtgt
    22021 aaactttgaa acttacatat tggagaaaaa aatatatgca aagataaata aagagatgct
    22081 tacaagagca tttgagaatt taatttataa tgctttgaca tttactccat ttgatggaaa
    22141 gataatttta tcaatggata aagaagatgg atttgcaatt attaaagttt ctgataatgg
    22201 aaaaggtata cctccagaaa atataccaaa ggtatttgac agattcttta cagaaagaga
    22261 taataatgag ccaaaagggc aagggctagg gttatatatt gtcaaatcca ttataagaga
    22321 gcatggcgga gaaatctttg tagattcaga actaggaaaa ggaactgttt ttacaataaa
    22381 attaagtcta tgttttttat aataatagct tatttaatat aaaagaataa tgatatttgg
    22441 gagtgattat aatgcaaact aagatattga taatagatgg agacaaggat aattgccaga
    22501 agctaaaagg atttctggag gaaaaagaaa taagtataga tttagcatat aattgtgaag
    22561 aagctattgg aaaaatattt agcaataaat atgatttaat atttttagaa ataattctaa
    22621 ctgatggtga tggatggact ctttgtaaaa aaattagaaa tgtaactact tgtccaattg
    22681 tttatatgac ttatataaat gaagaacaaa gcattttaaa tgctttaaat tctggcggag
    22741 atgattactt aataaagcct ctaaatttag aaatattata tgcaaaagta aaagctattt
    22801 taagaagaat gaactcatat gtaaataata atgaaaataa tacaaaatta gaggaatata
    22861 atagaactag tggagtaata aagttagaag acaaaataat aaaattgact ccaacagaaa
    22921 ataagctgtt aaactttttt atagagaatc ctgaaaagac tctgactact aaagagatat
    22981 atgaacatgt atggatgaat gagtacttag aggataacta tagtgtggta gttgcagtga
    23041 atggattaag aaagaaaata gagaaagatt ataaaaatcc tcagaaaatt ataacaataa
    23101 gaggagcagg atattatttt aataaagaat aataaatata ttaatctcat taataattgt
    23161 tataaatgtg aaatgctaac gatatctaaa ctaaattatt ataaaatagc tgactgtaat
    23221 ttaattgata aagcctattc ttctaggctt tgccagttaa attacagtca gttttattat
    23281 atgaaaaaat gcgtaacaga actattattt tatagattat atttgaaaag atagataaat
    23341 tgtatatcta aatctatata tattcatttt tatctttaat atatgttaaa taataaaata
//
LOCUS       DACTZW010000068        22632 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.068, whole genome shotgun sequence.
ACCESSION   DACTZW010000068 DACTZW010000000
VERSION     DACTZW010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22632
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.068"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(11..724)
                     /locus_tag="JAM15_13565"
     CDS             complement(11..724)
                     /locus_tag="JAM15_13565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2140 domain-containing protein"
                     /protein_id="HAT6799283.1"
                     /translation="MGKVAKILLSLIVIVLVLAGIVVYILTPKERYDVSSQNNKIIDE
                     EYLSKGSYINSMEVVKNPLRMVGKISVSEEEFKNLIYTLMQKHGINELENNFVEMKNG
                     KIKVAGPYKVFGLVNSQYELELRPTLKDGNLVVSLENVKIGKFKLSDKMLEKILSNYN
                     KKVPFEVNGNKITLEKSYLYPITLKNISIKKGNVDLDMEVEIDLKSQINGALGYLKDS
                     GKVQDILNHLINLKKTSVG"
     gene            1016..2680
                     /locus_tag="JAM15_13570"
     CDS             1016..2680
                     /locus_tag="JAM15_13570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase/YqeY domain fusion
                     protein"
                     /protein_id="HAT6799284.1"
                     /translation="MSNETNSSNFIKNIIINDLETGKHDSIITRFPPEPNGYLHIGHA
                     KSICLNFGLAKEFNGKANLRFDDTNPLKEDVEYVESIKEDVKWLGFDWNELNFASNYF
                     DEMYKRALILIKKGKAYVCDLTQEEMREYRGTLTEPGKESPHRNRTIEENLDLFERMK
                     NGEFKDGEKTLRAKIDMSSPNINLRDPIIYRISHSTHHNTGDKWCIYPMYAFAHPIED
                     AIEGITHSICTLEFEDQRPLYDWFVKECEMENIPRQIEFARLNINNTVMSKRKLKQLV
                     DEGIVDGWDDPRVPTISGIRRKGYTAEALRNFCSEIGVSKVNSTVDSQMLDYFLRENL
                     QPKAPLTMGVLRPLKLIITNYPEDKIEMLEIENNAKDESQGKRLVPFSRELYIEQDDF
                     MEEPVKKYFRFFPGNEVRLKGAYFVKCTDVIKDENGNVVEIHGTYDPETKSGSGFTGR
                     KVKSTIHWVDAKSAIPCEFRLFEPLILDDIPENEGKHFLEQINPNSLEILQGFVEPTQ
                     IKDAKPFDKFQFVRNGFFSIDNKYTTDEKFVFNRIVPLKSSFKPGK"
     gene            complement(2787..3686)
                     /locus_tag="JAM15_13575"
     CDS             complement(2787..3686)
                     /locus_tag="JAM15_13575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HAT6799285.1"
                     /translation="MKKVKLIYNPNSGEKKILSNLDTIIELYQEKNYLLIPYRLTIKE
                     PVKNAFKEVDSSYEHILIAGGDGTVDLVVNAMKELDIKIPIGILPTGTANDFSNALQI
                     SFDIKEAINEIINSKPKKIDIGKVNNKYFINVASAGMFTDVSQRINTDLKNSFGRISY
                     YIKGIEEALYMRKFKIKVSSEEMYYDGDMYLMLIFNGKTAGNINLAYKAEIDDGYLDV
                     IIFKGMPIPKSIPVLISVLRGDYLDQYNGNEILYFKTKKVHIECEDSLITDIDGEKGP
                     DFPLNIECIKDGIEVMGICSEKS"
     gene            complement(3713..4351)
                     /locus_tag="JAM15_13580"
     CDS             complement(3713..4351)
                     /locus_tag="JAM15_13580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016207911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HAT6799286.1"
                     /translation="MDQNLNWLNEKRIEKTIKSLENNNMKGYLVSNKEELLKKIEEIV
                     KVGSLVGCGGSMTLFETGVIDFIREKYNFLDRYAKDIKPEEMKEIYRKSFSADAYFTS
                     TNAITEDGELYNLDGNGNRVAAMIYGPDKVIVIAGVNKIVKDVDEAIKRTKTIAAPAN
                     CKRLSTNTGCKTTGICIDCSSPGRICCSYTLIKRQLTPERIHVIFLNEDFGY"
     gene            complement(4688..5686)
                     /locus_tag="JAM15_13585"
     CDS             complement(4688..5686)
                     /locus_tag="JAM15_13585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4003 domain-containing protein"
                     /protein_id="HAT6799287.1"
                     /translation="MEQSFINGKVNLLIENYKALNEVKGSWQMGLIQHSCALAFTLKN
                     KRISPRLVEERIELIKKNTGLFSNFRGYNMFYMATLLSFESNPESSFKMILDIYKELK
                     SEKFWGDTYLPLTASIVYENREKMDYLTCISKMKIIYDYMRKKHPFLTSSDDYCNIAL
                     IAIHSKNLDEDLEYIEKCYEFLNENGFYKGNDLQALSQILLFSDDRTMLKCKKTIELK
                     KAFKENDCKMNYYGYPIIGAISLLDYREDEIIEEIKNVSNKLKEEKGFGNWSLGKSNR
                     VMISSAIVASIYADLIRNENNIGSITNNIFLNIVVAIQIACVMAATSAAIASSSSN"
     gene            complement(5784..6359)
                     /locus_tag="JAM15_13590"
     CDS             complement(5784..6359)
                     /locus_tag="JAM15_13590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799288.1"
                     /translation="MKLKEALITCVVCSVCLTPLLVNGETKIDADHCKESIVNIDTIV
                     KSGKSFNSKYNQGMEDYKNSDEYKLKVQKEKLQNQLGIKIKNLVPITFEVSYYTSLNQ
                     ENGYGAITATGDDLEDGFVANNHLSFGTKIIVDGKLKTVMDRGSSKYFSNSNAIDVFV
                     PKWSNESESEYYDRVNNMGRHYKKGYIIVEE"
     gene            6675..6938
                     /locus_tag="JAM15_13595"
     CDS             6675..6938
                     /locus_tag="JAM15_13595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799289.1"
                     /translation="MIKNTKQITVEVNEILLQEISKITNDENNILTDLINESIVNYIL
                     ENKKHNIENKDLEEVIKFYKKENTEKPKSAARAIAEAKTHTLY"
     gene            complement(7367..7744)
                     /locus_tag="JAM15_13600"
     CDS             complement(7367..7744)
                     /locus_tag="JAM15_13600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HAT6799290.1"
                     /translation="MTITKIPPAELKVMKFIWSSDFTVASKDVIEAMEKLYNWKQTTT
                     LTLLSRLVNKQFLSARKIDRHTHYTVLIGEEEYLHFETKTFLDNMHGSSIESFMKSLF
                     KKGVNEEELNSVEKWVKDIKKDE"
     gene            8085..9197
                     /locus_tag="JAM15_13605"
     CDS             8085..9197
                     /locus_tag="JAM15_13605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAT6799291.1"
                     /translation="MNAFIRKRNKNYVVYLEFEDEKTGKRKQKNMGTFDKKREASKRL
                     NEVKESLYNDGFLVPSEITVSEFLLDFLNKYSENISLATYNNYVSICKNYINPSIGKY
                     KIQDLHPVHIQNYIDKLSYKLNPQSIKIHINILKLAIKRAYRLKLIKENVMDSIEAPR
                     YKKFKNEIYDREQMIKLLDLAKNTEMELPINLAIGLGLRISEVLGLTWDNIDFEENTI
                     TVNKITSRINGSVILKEPKTESSVRKISSPKELMSLLKEYKIKQNKNLLKSSIRNNNN
                     LLFFNKKCEPIAEDVMSKKFKRFLEKNELPHIRFHDLRHSHVTLLINSKVPIKVISER
                     VGHSNISTTLSVYSHVLKEMDKEASDKISESLFNAN"
     gene            complement(9405..9881)
                     /locus_tag="JAM15_13610"
     CDS             complement(9405..9881)
                     /locus_tag="JAM15_13610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799292.1"
                     /translation="MVKKRLVAVVLSLAMISVGNFSYAHSGGHNSSGGHHNKNKSELT
                     RYYCGGHSAHQPNKGFCPYASTKENSGVTISSVHNEKNHKNYFAEKGYNKGYEDGCKG
                     LYNLSVTEAKSDNLYEKEILKSSYEKGYLIGYNEYKAKKVDDVMKKMLDIPMLASI"
     gene            complement(10080..11705)
                     /locus_tag="JAM15_13615"
     CDS             complement(10080..11705)
                     /locus_tag="JAM15_13615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAT6799293.1"
                     /translation="MLQVTGVGLRFGDKELFKDVNLKFTKGNCYGIIGANGAGKSTFL
                     KILSGEIEPNTGSISITDKERMSVLKQDHFEYEEETVLNVVIRGHERLWNIMKEKDAL
                     YMKEDFNEEDGIKAAELEGEFAELDGWDAETNAEKILMGLGITKDMHYKQMKELVGGE
                     KVKVLLAQSLFGKPEILLMDEPTNHLDFKSINWLNNFIMDLEESIVIIVSHDRHFLNQ
                     ICTNIVDVDFGKIQMYVGNYDFWYESSQLALQLAKDQNKKTEEKIAQLKEFIARFSSN
                     ASKAKQATSRKKQLEKLEVEDIQPSRRRYPYVGFTPAREIGNEVLEVHNLTKTIDGVK
                     VLDNVSFRLDRDDKVVFMGDEIATTALFNIVMGELEPDSGEYKWGVTTSQDYLPKNHN
                     KFFDGVEYSLVDWLRQFSEEKSESFIRGFLGRMLFSGEEALKEAQVISGGEKVRCMLS
                     KLMLSNANVLVLDDPTNHLDLESITSVNKGLEKFPGVLLFTSHDHEFISTIANRIIEI
                     TPNGIMDRKMDFDEYLESKEIQDQLAKMYGKDK"
     gene            complement(12043..13062)
                     /locus_tag="JAM15_13620"
     CDS             complement(12043..13062)
                     /locus_tag="JAM15_13620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-binding protein"
                     /protein_id="HAT6799294.1"
                     /translation="MKLIKTIDAVGQVLCHDITQIIPGEFKGRKFKKGHIVKEEDIPV
                     LLSLGKDNLYVWEKSEGMVHENEGALFLKELTAGENLDFSEIKEGKIDFIAACDGLLK
                     IDVDALFDLNCVGEIMMATLHNNFIVNKGLKVAGTRVIPLVIDEKKLEDAKKVVGNRK
                     IVNVVPFKPKKVGIVTTGNEVFYSRIVDKFGPVIEEKVKGFGCEVIGQTICPDDKEII
                     KSAIKEFISQGAELICCTGGMSVDPDDVTPTAIKETGADLVTYGSPILPGAMFLLAYY
                     GEVPIMGIPGCAMYHKTTVFDIVLSRVLIDEKLDKYDIARYGHGGLCMNCDVCTYPAC
                     NFAKI"
     gene            complement(13059..13628)
                     /gene="mocA"
                     /locus_tag="JAM15_13625"
     CDS             complement(13059..13628)
                     /gene="mocA"
                     /locus_tag="JAM15_13625"
                     /EC_number="2.7.7.76"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor cytidylyltransferase"
                     /protein_id="HAT6799295.1"
                     /translation="MINAVIMASGFARRMGANKLLLNYKGCSIIEHVFREVSKIDFHQ
                     VVVVSQYEEVLLLCNKYGFEYIDNKNANIGQSESIKLGVLNSSKCDGYMFFVGDQPFI
                     DNLYIDKIINTFKLDRDFIVIPRYKDMCGNPVIFPYSKKEELLALKEDEKGKTILKNS
                     SKIKYVEVPKEMLFDIDTKMDYERIGGKL"
     gene            complement(13735..14457)
                     /gene="yqeC"
                     /locus_tag="JAM15_13630"
     CDS             complement(13735..14457)
                     /gene="yqeC"
                     /locus_tag="JAM15_13630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenium-dependent hydroxylase
                     accessory protein YqeC"
                     /protein_id="HAT6799296.1"
                     /translation="MELSNIIEKNEIITVVGAGGKTSFINYFANFYRDKLKVLLTTTT
                     KIYVPNDYDNIIITIDGTVIPSICHGITVCGSYINNENKLVSIDSSILDEIVDQFDLV
                     LIEGDGSKRKKLKGWNAKEPVVYHKTTKTIGILDITSFGMNINEENIHRVEIFKKIAN
                     LDTSSINSSSTVSIENLKNIVLNPNGLFKNYSGKRVLFINKVENEKYKNLAIKLIENI
                     KEYESEIEIFYGSVKQKFCVRY"
     gene            complement(14640..15917)
                     /gene="tnpB"
                     /locus_tag="JAM15_13635"
     CDS             complement(14640..15917)
                     /gene="tnpB"
                     /locus_tag="JAM15_13635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family element transposase accessory
                     protein TnpB"
                     /protein_id="HAT6799297.1"
                     /translation="MSNRIKNIHYGTQRQQLKNLTKKEYQALREMCFLAKNLYNVGTY
                     NVRQHYFNQGEHLNYEANYHVCKENENYKLLNSNIAQQILKEVDSSFRSFFGLIKLAK
                     EGKYDFRGIKSPKYLDKEGFFSIIIGQIRIKEDGILNVPMSPAFKKLYGKVSIKVPQN
                     ILEKKIKEIRIIPKHKARFFEIQYCYEIPKSEEVSNQKNALAIDLGLENLCTCVTNLG
                     DSFIIDGKRLKSVNQWANKQNDKIESLKLKKNITAITRKQFKVWNKRNNQVKDYVNKT
                     CFYIIDYCVKNNIGNLIVGYNAKLEKSDNMERKIYRNFIRIPFGEIKGKLEYLCKIKN
                     INFIRQEESYTSKSDFFADDFLPDINVDNVKKYDFKGERITRGQYKSSVGIIINADVN
                     ASLNILKKSQVVNLSNLQNNPQILKQPQRVRIS"
     gene            complement(16056..18362)
                     /locus_tag="JAM15_13640"
     CDS             complement(16056..18362)
                     /locus_tag="JAM15_13640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HAT6799298.1"
                     /translation="MINKGIRKIDSTAIVTGKPLYTEDLIMHKDVLTLKLLRSPHAHA
                     KIKNIDTSKAEKIPGVVGIYTYKDVPQVRYCVPGQTEPEASPYDRVLLEDTVRFIGDE
                     VALVAAEDEKTALKALKMIKVDYEVLKPVFDAREAEGNEVVIHPEKDIVEPYPFGLDA
                     KNNIVSKEFFEFGDVEAKLKESDFVVESSYKTQSQSHCMMETHRSYSYKDINDRIVVV
                     SSLQSPHNVKRIIRKVLGIPSSKIRVIKPRIGGGFGGKNIAATDIFTAFVTMKTGRPA
                     KFVFTRSETFVGSNSRHEMFFDVKVGADKEGNLKAIELKSLNNTGAYGGNGVSVSSES
                     GHNTLPIYNDIDAVRFNARTVYTNRLPAGALRGYGATQGIFAIDSAIDELAHKIGMDP
                     LEFRIKNIIDRYTNGKAAEDEILSCELRQCIEKGKKLINWDDKYPCKDIGNNKVRAVG
                     MAVANHGSGIPRVDMATVTIRMDEDGTYKLLSGLADLGQGADTIQAQIAAEALNTTVD
                     RISIYTGDSDLCPYDTGAFASCTTTVTGNATIKTANKLKDILLSVAESKLGFKKEDLE
                     LGKDRVFVKNDNSKFVLLEELGRESVGGIGFASDDVPVVLEATESFGMLKKIKPFIAG
                     FAEIELDKNTGEYKVINFACVPDCGTVINPTLARIQVEGGVMMCIGFAMYEDPIFDKD
                     GRLLTDSFLQYKVPTKKEVGNILVDFAENFDPGGPYGAKSLGEIVIHTPAPAIANAIF
                     NATGVRLRELPMTFEKVYMGMKNNNKQL"
     gene            complement(18355..19149)
                     /locus_tag="JAM15_13645"
     CDS             complement(18355..19149)
                     /locus_tag="JAM15_13645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HAT6799299.1"
                     /translation="MVTIKEYSIPQSLEEAYKILISKKNNVILGGCGFIKLSNKNIGT
                     AIDLKDINLNYIKEDEKNILIGADTSLRSLEIDKTIKNYCSGILSSAVSNIVGVQFRQ
                     GARIGASVFSKYGFSDLIPALLVVGAKVRLYNKGILELSEFLDSELSRDILVEVILPK
                     KDAIAVFDSIRKCTGDFSVLNSAMLKENDTYKIAIGARPQKARLALEASNILNKEKDI
                     DKASIVASKELTYGSNMRASKEYRKDMASALVKRMYNAIEEGMYND"
     gene            complement(19255..20613)
                     /locus_tag="JAM15_13650"
     CDS             complement(19255..20613)
                     /locus_tag="JAM15_13650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine permease"
                     /protein_id="HAT6799300.1"
                     /translation="MKAKSTSKFELDGIPPLKEAIPLGLQHLMAMVIGSCLPAILIAN
                     AAGLNHKMSTLLIQATLVFAGLSTLLQLYPIPLFKGFKLGGGIPVIMGATAVFIGAGV
                     SVASKYGLPVLFGSQIIAGIVIIIIGFGLKKIRFIFTPAVSGTIVACMGLGLFPIAIK
                     NLAGGMGNETFGNPINFIVGISVSLMILGLNKYGKGLFKDASILVSIIFGYILSLILG
                     IVNFSSIQEFTLVALPKPLAFGLDIRLEVVVMFSIIYLVEIADIMGACTLSAVGGLNR
                     QVTDEELSSAVLGNGVLSTIGALFSATPMGMFGQNSAIVSNTKVVSKFVLAIGGIGLF
                     LAGISPLLANLIRTIPPCVVGGATLVIFSTLTTSGLRLVSMDGFNQENSMILGLSMAS
                     GIGFMVAPQVLEKFPKFIETLLADSSVVSGAMVAIIIQALYMVKFPGNKSDKVEDKNK
                     SL"
     gene            complement(21961..>22632)
                     /locus_tag="JAM15_13655"
     CDS             complement(21961..>22632)
                     /locus_tag="JAM15_13655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799301.1"
                     /translation="EVRQEINIMKEDISEVRQEMTVMKEDMSEVKQEINVLKEDMSEV
                     RQEINIMKEDMFEVRQEMTVMKEDTSEVKQEINVMKKDMSEVRQEITVMKEDVSEVKS
                     EVNFMQNKINNINEDMNGIKDEVSIANEKLYGIEIKIDSLECEDKSMKEIQIEQNNIL
                     GSLLHNSEINKATHDNIEHNIAYIKGDTNSIKEDIAEIRRDLNLVELATSKNWSDIVK
                     LKSVK"
BASE COUNT         7527 a         3823 c         2359 g         8923 t
ORIGIN      
        1 ttctatattt ttaaccaaca gatgttttct tcaaattaat cagatgattt agtatatctt
       61 gaacctttcc agagtccttt aaatatccta atgccccatt tatttgtgat tttaaatcta
      121 tttctacttc catatccaaa tcaacatttc ctttttttat agatatattt ttaagtgtta
      181 ttgggtaaag ataacttttt tccaaagtaa tcttatttcc attaacctca aatggaactt
      241 ttttattgta gttacttaat attttttcta gcattttatc acttagttta aattttccaa
      301 ttttcacatt ctcaagactt acaactaagt ttccatcctt taaagtaggt ctcaattcaa
      361 gttcatattg actatttacc aaaccaaata ccttatatgg tcctgctacc tttattttac
      421 catttttcat ttcaacaaaa ttattttcaa gttcattaat tccatgcttc tgcatcaatg
      481 tatatattaa atttttaaac tcttcctctg aaacagatat ttttccaacc attctaagtg
      541 gattttttac tacctccata gaatttatat atgagccttt tgataaatat tcttcatcta
      601 tgattttatt attttgtgaa ctaacatcat atctttcttt tggtgtcaag atatatacaa
      661 caattcctgc aagtactaaa acaataacaa ttaaacttaa caaaatcttt gcaacctttc
      721 ccataatcgt ctcctttaca aatctgtcat cagatttaaa ataaatttag ataactaact
      781 tcacataata ttcttaacaa tatacatact ataatacagt cttttaaaaa ttaattcaac
      841 caatctaatg ttttgtaaat aaactgtaaa aacatgtttt tagtataaaa gttaatattt
      901 tgcataatac tcttaattac acctttattt ttttctaatc ttggattaaa attaatatta
      961 tgcaatacag tgtagtgttc tgtattataa tcaaattaaa taggaggtat agaatatgtc
     1021 aaatgaaacg aactcatcta actttataaa gaatattatt ataaacgact tagaaacagg
     1081 aaaacatgac agtatcataa ctcgttttcc acctgagcca aacggatatt tacatattgg
     1141 tcatgcaaaa agtatatgtc ttaattttgg attagctaag gagtttaatg gaaaagctaa
     1201 tttaagattt gatgatacaa acccattaaa agaggatgtt gaatatgtag agtccataaa
     1261 agaagatgta aagtggttag gatttgattg gaacgagtta aattttgcat ctaactactt
     1321 tgatgaaatg tataagagag ctttaatact aataaaaaag ggtaaagctt atgtatgtga
     1381 tttgacacaa gaggaaatga gagaatatcg tggtactcta actgaaccag gaaaagaaag
     1441 tcctcataga aacagaacta ttgaagaaaa ccttgattta tttgaaagaa tgaaaaatgg
     1501 tgaatttaaa gatggtgaaa aaacattaag agccaaaata gatatgtctt ctccaaatat
     1561 aaaccttaga gacccaatta tatatagaat atctcattca acacaccata atacaggaga
     1621 taaatggtgc atatatccta tgtatgcttt tgctcatcca attgaagatg caattgaagg
     1681 aataactcac tctatatgta ctttagagtt tgaagaccaa agacctcttt atgattggtt
     1741 tgttaaagaa tgtgagatgg aaaatatacc tagacaaata gaatttgcta gacttaatat
     1801 aaataatact gtcatgagta aaaggaaatt aaaacaactt gtagatgagg gtattgttga
     1861 tggttgggat gaccctcgtg ttcctacaat atccggaatc agacgtaagg gatatactgc
     1921 agaagcattg cgcaatttct gtagtgaaat aggggtatca aaagttaact ctacggtaga
     1981 tagtcaaatg cttgattatt tcctaagaga aaacttacaa ccaaaggctc ctcttactat
     2041 gggagtttta agacctttaa aacttattat aactaattac ccagaagata agattgagat
     2101 gcttgaaata gagaataatg ctaaagatga atctcaagga aagagattag ttcctttctc
     2161 tagagaattg tatatagaac aagatgattt tatggaagaa cctgttaaga aatattttag
     2221 atttttccca ggaaatgaag tccgtttaaa aggtgcttat tttgtaaaat gtactgatgt
     2281 aattaaggat gaaaatggaa atgtagttga aatacatggt acttatgacc ctgaaactaa
     2341 gagtggctct ggctttacag gacgtaaggt aaaatctaca atacattggg ttgatgctaa
     2401 atcagctata ccatgtgaat ttagattatt tgaaccatta attcttgatg atatacctga
     2461 aaatgaaggt aaacatttct tagaacaaat aaatcctaat tcattggaaa tattacaagg
     2521 ttttgttgaa cctacacaga taaaagatgc taaacctttt gataaattcc aatttgttag
     2581 aaatggattc tttagtatag ataataaata tacaactgac gaaaaatttg tatttaatag
     2641 aatagttcct ctaaaaagtt cttttaaacc aggtaaataa tcttacaatc aaaaaatgaa
     2701 gacttaaaat ataaattact tctactataa ataaacttag ttagaagtaa ttttttattt
     2761 gagtcttcat catttacttt aaatgattaa cttttttcac tacagattcc cataacttct
     2821 attccatctt ttatgcattc tatgttaaga ggaaaatctg gtcctttttc tccgtcaata
     2881 tctgttataa gtgaatcttc acattctata tgcacctttt tagttttaaa gtatagtatt
     2941 tcatttccat tatattgatc taaataatca cctctaagca cacttatcaa aactggtatt
     3001 gattttggta ttggcattcc tttaaaaata attacatcca aatatccatc atctatttca
     3061 gccttatatg ctagatttat atttcctgct gttttgccat taaaaatcaa cataagatac
     3121 atatctccat cataatacat ttcctcagaa gatactttta tcttaaattt cctcatatac
     3181 aatgcttctt ctattccctt tatataataa gaaattcttc caaatgaatt ttttaagtct
     3241 gtgtttatcc tttgtgatac atctgtaaac ataccagcac ttgcaacatt tataaagtac
     3301 ttattattga ctttccctat gtctattttc tttggttttg aatttatgat ttcatttata
     3361 gcttctttta tatcaaatga aatttgaaga gcatttgaaa aatcatttgc agttcctgta
     3421 ggcaaaattc caattggaat ttttatgtct aattctttca ttgcatttac tactaaatct
     3481 acagtaccat ctccaccagc tatcaatatg tgttcataag aactatcaac ttccttaaat
     3541 gcattcttta caggttcttt aatagttaat ctatagggta tcaataaata atttttttct
     3601 tgatataatt ctatgatagt gtctaaattt gataatatct ttttttcacc tgaattagga
     3661 ttgtatataa gttttacttt tttcattatt tctccttact cattttattc ttttagtatc
     3721 caaaatcttc atttaaaaaa atcacatgta ttctttctgg tgttaattgt ctttttataa
     3781 gtgtataact acagcatatt cttcctggac ttgaacagtc tatacatata ccagtagtct
     3841 tacatccagt atttgtactt aatcttttac aattagctgg agcagctatt gtttttgttc
     3901 tttttatagc ttcatctaca tctttaacta ttttatttac tcctgctata actattactt
     3961 tatcaggtcc atatatcata gcagcaactc tattcccatt cccatctaaa ttgtaaagtt
     4021 ctccatcctc tgttatcgca ttagtacttg taaaataagc atctgcagaa aatgactttc
     4081 tatatatttc tttcatttct tctggtttga tatcttttgc atatctatca agaaaattat
     4141 atttttctct tataaaatca atcactcctg tttcaaataa ggtcatagaa cctccacatc
     4201 ctactagaga acctacttta actatttctt caattttttt aagaagctct tctttgttac
     4261 ttactaaata ccctttcata ttattgtttt ccagagattt tattgttttt tctattcttt
     4321 tttcattaag ccaatttaaa ttttgatcca ttttaacttc ccccttattt ttaatatgta
     4381 cttaattatt tataaacttt attgtcttta taagtttatt ttagtacatc taaaaaaaaa
     4441 tacaatataa aacttaaata gttttacata attttttcca aaataactta ctcaatcaaa
     4501 aaaggaaagt agatgtacta ttctactttc cctatattgt atgtagtatt tattgcctaa
     4561 aatctatata ttaattatat gtttcatatt atataatatc acagttaatt aaaatgtaat
     4621 actatcttct ttttaaacat ataaattgta ttattaaatt taatatatcc aacttcaata
     4681 aatcttatta atttgatgaa gaagatgcta tagctgcact tgttgctgcc attacacatg
     4741 caatttgaat agcaacaaca atatttaaaa atatattatt agttatagag cctatattat
     4801 tctcatttcg tatcaaatct gcataaattg aagctacaat agcagaacta atcattactc
     4861 tattactttt tcctaaagac caatttccaa agcctttttc ttctttaagt ttatttgaaa
     4921 cattttttat ctcttctatt atttcatctt ctctataatc taataatgaa attgctccta
     4981 ttattggata tccataataa ttcattttac aatcattttc tttaaatgct tttttaagtt
     5041 caatagtctt tttacattta agcatagttc tatcatcact aaataaaaga atttgggata
     5101 atgcttgtaa atcatttcct ttataaaaac cattttcatt tagaaattca taacattttt
     5161 ctatgtattc taaatcttca tctaaatttt ttgaatgaat tgcaataagt gctatattac
     5221 aatagtcatc actagaagtt agaaatggat gttttttcct catgtaatca tatattattt
     5281 tcatttttga tatacatgta agataatcca ttttctctct attttcataa actattgatg
     5341 ctgtaagtgg taaatatgta tcgccccaaa acttttcact tttaagttct ttgtatatat
     5401 ctaaaatcat cttaaaacta ctttctggat ttgattcaaa cgaaagtagt gttgccatat
     5461 aaaacatatt atatcctcta aaattagaga ataatccagt atttttttta ataagctcta
     5521 ttcgttcttc cactaatcta ggacttattc tcttgttctt aagagtaaat gcaagtgcac
     5581 aactatgttg tatcaatccc atttgccaag aacctttaac ttcatttaat gctttgtaat
     5641 tttctattaa taagtttact tttccattta taaacgattg ttccatattg ccctcctagt
     5701 aatatatctc attgtactaa tagttttata tttattatat atatattaaa tactacaatc
     5761 aatacatatt acttcaaaga acatcattct tcaacaataa tgtagccttt tttgtaatgt
     5821 cttcccatat tattgactct atcatagtac tctgattcac tttcattact ccatttgggc
     5881 acaaatacat ctattgcatt agaattacta aaatacttac tagaccccct atccataaca
     5941 gtttttaatt ttccatctac aataatctta gttccaaaac tcaagtgatt gtttgctaca
     6001 aaaccatctt ctaaatcatc tcctgtagca gttatcgctc catatccatt ttcttgatta
     6061 agacttgtgt aataactaac ttcaaaagtt ataggtacta aattctttat tttaatacct
     6121 aactgatttt gtagtttctc cttttgtact ttcaacttat actcatcact atttttataa
     6181 tcttccatac cttgattata cttggaatta aagcttttac ctgactttac tatagtatct
     6241 atatttacta tagattcttt acaatgatct gcatctattt ttgtttctcc atttaccaat
     6301 aatggagtta aacatacact acatacaaca catgtaatca atgcttcttt aagcttcata
     6361 aattcccccc ttattatttt gatatattag catatttaat attatatgtc tatatttaga
     6421 tttaaatgcc acacccattt actttaagaa gttgtcttat atttaattca ccttaaacac
     6481 ttataaatcc tctatcttag aatcatatag aataaagctt ttatcgttaa atatttttta
     6541 ttaatctttt aaaatctaaa gctactttat ttaattttct cttttttaga atttaagaat
     6601 taaaattcta taattttaaa acatattgaa tttatttttt tgagatgata taattttctt
     6661 aagaggtggt tgatatgata aaaaatacaa aacaaattac agtagaagtt aatgaaattt
     6721 tattacaaga aatatctaag ataactaatg acgaaaataa tattttgaca gatttgataa
     6781 atgaatcaat tgtaaattat attcttgaaa acaaaaaaca taacattgaa aataaagatt
     6841 tagaagaagt gattaaattt tacaaaaaag aaaatactga aaaacctaaa agtgcagcaa
     6901 gagctatagc tgaagcaaaa actcataccc tgtattaatc aaataaaaaa gttcctaaaa
     6961 actaggaact tttttatatt aataattatt aatatatctc aatatttatc tcaaatttat
     7021 caatataagc atgtttaata caatctattg tatacttatc ttaccctaga aataatcaaa
     7081 acaaaaatta tgccctttat atctaacaat taatttacat gattaatata caaaaattct
     7141 gacttttaaa ttcgtataca atatcaaact aaaataatat taatgacaaa cccaatataa
     7201 attaaattca aacaggtttg attttacatc aaacttattg tattaatatt aaataacaag
     7261 acaaaatatt tataaaaatt acaaatttta cataaaactt tatattttat tcatttaact
     7321 aattattgta aaaactattt attttatgat aattaactac accaaattat tcatcttttt
     7381 taatatcttt aacccatttt tcaacagagt tcaattcttc ttcatttacc ccctttttga
     7441 acaaggattt cataaaactc tcaatagaac ttccatgcat attatctaaa aaagtttttg
     7501 tttcaaaatg taaatactct tcttctccaa taagaactgt ataatgtgta tgtctatcaa
     7561 tctttcttgc acttaagaat tgcttattta ctaatcttga taaaagtgtt agtgttgtag
     7621 tttgcttcca attatatagt ttttccatag cttcaatgac atcttttgat gctactgtaa
     7681 aatctgaact ccaaataaat ttcatgactt ttaattctgc tggtggtatc ttagtaatag
     7741 tcatatgatt ttacactcct ctcaaacttc tacataatta aatactatat taatagactt
     7801 ttcgagtcaa aggttttatt taaaatatct catccaaatt tattaataca aaaaatttat
     7861 atttttattc aaaattaaac acacaatcta ttaatataaa gataaatatc tattctataa
     7921 gtataacaga ttatcaaatt aaaattctaa tatttgacat aatatataca ttttttaaat
     7981 aaatatatac aatgtattaa aatgtatgca actctatttc aaaattattt tgtgatatat
     8041 atatgttata ataaatgtat aaaattttga ttggtgggtt atatatgaat gcatttatta
     8101 gaaaaagaaa taaaaactat gttgtttacc tggaatttga agatgaaaag acaggtaaaa
     8161 gaaaacaaaa aaatatgggt acttttgata aaaaaaggga agcaagtaaa agactaaatg
     8221 aggtaaaaga aagcttatat aatgatggtt ttttagtacc aagcgaaatt acagtgtcag
     8281 aatttctatt agattttcta aataaatata gtgaaaatat atctttagct acatataata
     8341 attatgttag tatttgtaaa aattacatta atccatctat tggaaaatat aaaatacaag
     8401 acttacatcc ggttcacata caaaactaca tagataaact atcttataaa ctaaatcctc
     8461 aatcaattaa gattcatata aatatattga aacttgcaat aaaaagagct tatagactca
     8521 aattaataaa agaaaatgtt atggatagta tagaggctcc aagatataaa aaatttaaaa
     8581 atgagattta tgatagagaa caaatgataa aattattaga tttagcaaaa aatacagaaa
     8641 tggaattacc tattaatttg gctattggat taggtcttag aatttcagaa gttttaggtc
     8701 taacttggga taatattgat tttgaagaaa atacaataac agtaaataag ataacttccc
     8761 gaattaatgg ttctgttatt ctcaaagagc caaagacaga aagctctgtt agaaaaatat
     8821 cttctcccaa agaattaatg tctttattaa aagaatataa aataaaacag aataaaaatt
     8881 tattaaaatc ttccattaga aataataata atttgttgtt tttcaataag aaatgtgaac
     8941 ctattgctga agatgttatg agtaaaaaat ttaaaagatt tttagaaaag aatgaattac
     9001 ctcatattag attccatgat ttaagacact cacatgttac tttacttata aattctaaag
     9061 tacctataaa ggttatatcc gagagagtag gacactcaaa tataagtact actctaagcg
     9121 tttattctca tgtacttaaa gaaatggata aagaggcttc tgacaaaatt tctgaaagtt
     9181 tatttaatgc taattaatat taatttatct tagctttaaa ttagcttagc ttattgagat
     9241 agattcatta atattaaatg tatctatctc aaattaataa ctacttaaat aatctgtttt
     9301 attttaattt atcgcctcag ttattacact tttttacgaa aaattatact ttacaataaa
     9361 aaagatattt ccttatagaa agtatctttt taaatactat tttattatat acttgctaac
     9421 attggaatat ctaacatctt cttcattaca tcatctactt tttttgcttt atattcattg
     9481 tatccaatta aatatccttt ttcatatgaa ctttttaaaa tctctttttc atataaatta
     9541 tcagatttgg cttctgtgac acttaaatta taaagccctt tacacccatc ttcataacct
     9601 ttattatacc ctttttctgc aaaatagttt ttatgatttt tttcgttatg tactgaagat
     9661 attgttactc cagaattttc ttttgtacta gcataaggac aaaaaccttt atttggttga
     9721 tgtgctgaat gtcctccaca ataataacgt gttaactctg atttattttt attatgatga
     9781 cctcctgatg aattatgccc tcctgagtga gcatatgaaa aattccctac actaatcata
     9841 gctaaactca atactacagc tactaacctt ttcttaacca taatctattc cccccaaaat
     9901 gttatatatt tttattatat catctactat attatattta aattcttaat atacaaaata
     9961 ttactctatt ctgctaataa acatatttaa acaacataaa aaacctccta atatttgatt
    10021 aaaaatttac acactcatgc atagcatgta tcaaatatta aaaggtttta tactaataat
    10081 tatttatctt ttccatacat tttagctaat tggtcttgta tctctttact ttctaaatac
    10141 tcatcaaagt ccatttttct atccattatt ccatttggag ttatctctat aattctattt
    10201 gctatagtag atataaattc atggtcatga gaagtaaata aaagcactcc tgggaacttt
    10261 tcaagtcctt tatttacaga agttatactt tctaggtcta agtggttagt agggtcatct
    10321 aatacaagta catttgcatt tgaaagcatt aacttactaa gcatacatct aaccttttct
    10381 cctccagata taacttgagc ttcttttaat gcttcttcac ctgagaataa cattctacct
    10441 aaaaatcctc ttataaaact ttcacttttt tcttcagaga actgtctaag ccagtcaacc
    10501 aaagaatatt ctactccgtc aaaaaactta ttatgatttt ttggaagata atcttgagaa
    10561 gtagttactc cccatttata ctctccactg tctggttcaa gttctcccat aactatgttg
    10621 aaaagtgcag tagtagctat ttcatctccc ataaatacta ctttatcatc tctatccaat
    10681 ctaaatgaca cattatcaag aaccttaacc ccatctatag ttttagttaa attgtgtact
    10741 tctaaaactt cattcccaat ttctcttgca ggtgtaaatc ctacatatgg atatcttctt
    10801 cttgatggtt gtatatcttc aacttctaat ttctctaact gtttctttct tgatgttgct
    10861 tgtttagcct ttgaagcatt agaactaaat ctagctataa attcctttaa ttgagctatc
    10921 ttttcttcag tctttttatt ttggtcctta gccagttgta aagccaattg acttgactca
    10981 taccagaaat catagtttcc aacgtacatt tgtattttac caaaatctac gtcaactata
    11041 ttagtacata tttgatttag gaaatgtcta tcatgtgata ctattataac tatagactct
    11101 tctaaatcca ttataaaatt atttaaccag tttattgatt taaaatctaa gtggtttgta
    11161 ggttcgtcca ttaatagtat ttcaggctta ccaaaaagtg attgtgctaa caatacctta
    11221 accttttccc caccaactag ttccttcatt tgtttgtaat gcatatcttt cgttatgcca
    11281 agacccataa gtattttctc agcattagtt tctgcatccc atccgtcaag ctctgcaaac
    11341 tcaccttcaa gttcggcagc ttttatccca tcttcttcat taaagtcttc cttcatatac
    11401 aatgcatctt tttctttcat tatgttccaa agtctctcat gacctcttat aacaacattt
    11461 aaaacagttt cttcttcata ttcaaagtgg tcctgtttta aaactgacat tctttcttta
    11521 tcagttatag atatactacc tgtattaggc tctatttctc ctgataatat ttttaaaaaa
    11581 gtagattttc ccgcaccatt agctcctatt attccatagc aattaccttt agtgaatttt
    11641 aagttaacat ctttaaatag ttccttatca ccaaatctaa gtccaacacc tgtaacttgt
    11701 aacattaata tattttcctt tctttttgct cataatttat tttatcataa aactttgata
    11761 acatttttat tatatattat cacgtaaata gtatattttt tatactaaat ttgtgaaata
    11821 tttattaaaa taatactaaa aattgtaaat ttataaaaat taacaatctc ttatattata
    11881 cttataaaga aatcaaattg caactttatt cattctttta cacattgaaa ataagttatt
    11941 ataatttcta aataaatatg cttttcttaa aacatcattc tagctgtttt gtttcatatt
    12001 taaaaagagt acttaatttg taaatactct tttttaataa ctttatattt tagcaaaatt
    12061 acatgcagga taagtacata catcacagtt catacaaagg ccaccatgac catatctagc
    12121 tatatcatac ttatcaagct tttcatcaat taaaacccta gataaaacta tatcaaatac
    12181 tgtagttttg tgatacattg cgcatcctgg tatacccata attggaactt ctccataata
    12241 agcaagtaaa aacatagctc ctggtaatat tggtgaacca tatgtcacta aatcagctcc
    12301 agtttctttt atagctgttg gcgtaacatc atctgggtct acactcatcc cgccagtaca
    12361 acagataagt tctgctcctt gacttataaa ttcttttatt gcactcttta taatttcttt
    12421 atcatctggg catatagtct gtcctataac ttcacaacca aagcctttta ctttttcttc
    12481 tattactggt ccaaatttat caacaattct gctataaaac acttcatttc ctgtagtaac
    12541 aattcctact ttcttaggtt taaaaggtac tacatttact atttttctat taccaactac
    12601 tttttttgca tcttctaatt ttttctcatc tataaccaaa ggtatcactc ttgttccagc
    12661 tacttttaaa cctttattta ctataaaatt attatgaaga gtagccatca ttatttctcc
    12721 aacacaattc aaatcaaaaa gtgcatcaac atctatcttt aatagaccat cacatgctgc
    12781 tataaaatct atttttcctt cttttatttc actaaaatct aaattttctc cagcagttag
    12841 ttcttttaaa aacaatgcgc cttcattttc atgaaccatt ccttctgact tttcccatac
    12901 atacaaatta tctttaccaa gagataataa cactggaata tcttcttctt ttactatgtg
    12961 acccttttta aattttcttc ctttaaattc tccaggtatt atttgagtta tgtcgtgaca
    13021 taaaacttgt ccaacagcat ctatagtttt tattagcttc ataatttacc cccgattctc
    13081 tcatagtcca tttttgtatc gatatcaaat aacatttctt taggaacttc tacatacttt
    13141 atttttgatg aattttttaa aatggtttta cctttttcat cttctttaag tgccaacaat
    13201 tcttctttct tactatatgg gaatatgact ggatttccac acatatcttt gtatcttgga
    13261 attactataa aatctctatc taatttaaaa gtatttataa ttttatctat atataagtta
    13321 tcaataaatg gctggtctcc tacaaagaac atataaccat cacattttga gctatttaaa
    13381 actcctaatt ttatagattc actttgacct atatttgcat ttttattatc tatatattca
    13441 aaaccatatt tattacacaa taacaaaacc tcttcatatt gacttactac tacaacttga
    13501 tgaaaatcaa tcttgctaac ttctctaaat acatgttcta ttatagaaca gcctttataa
    13561 tttaataaaa gtttatttgc tcccattctt ctggcaaagc ctgatgccat tatcactgca
    13621 tttatcatat atatcatcct tggtatttat aatatattga tagttctatg atttttataa
    13681 tatctctatt gatattatct atatatataa tatcatataa actattttaa tacttcaata
    13741 tcttacacaa aatttttgtt ttacgcttcc ataaaatatc tctatttcac tttcatattc
    13801 tttaatattt tctattaatt ttatagctaa atttttatat ttttcatttt caactttatt
    13861 aataaataat actctttttc cagaataatt tttaaataat ccatttggat ttaatactat
    13921 attttttaag ttttcaatac ttactgtaga actactatta atactacttg tatctaaatt
    13981 tgctattttt ttaaatattt ctactctatg tatattctct tcattaatat tcattccaaa
    14041 tgatgttata tctaatatcc ctatggtttt tgtagtttta tgatatacta ctggttcttt
    14101 agcattccaa cctttaagtt tttttctctt tgagccatct ccctctatta aaactaaatc
    14161 aaactggtct acaatttcat ccaaaataga ggaatcaata cttactaatt tattttcatt
    14221 atttatataa ctgccacaca ctgttattcc atgacaaata gatggaataa cagttccatc
    14281 tattgtaata attatattgt cataatcgtt tggtacatat attttagttg ttgttgtaag
    14341 aagaactttc aatttatctc tataaaaatt tgcaaaatag tttataaacg aagtttttcc
    14401 tcctgctcca actacagtta ttatttcatt cttttctatt atatttgata gttccacact
    14461 ttcacctctt ataaccagtt ttctaatctc ttaattatta tagttagacc tttttagtaa
    14521 aagtgatttt tgaaattcca taaactcgaa agtaaataga ttctgttgta aacaacaagg
    14581 cggatccaat tcgccgctaa gctgtaagct tacgctatca gtttatcttt taaatataat
    14641 taagatattc ttactctctg tggttgcttt aatatttgag gattattctg taaattagat
    14701 aaattaacta cttgtgattt ttttagtata ttaagactcg catttacatc tgcatttata
    14761 atgattccaa cactggattt gtactgtcca cgtgttattc tttccccttt aaagtcatat
    14821 tttttaacat tgtccacatt gatatcaggt agaaaatcat cagcaaaaaa atcagactta
    14881 ctagtatagc tttcttcttg cctaataaaa ttgatatttt ttattttaca tagatattct
    14941 aattttcctt ttatctctcc aaatgggatt cttataaaat ttctatatat ttttctttcc
    15001 atattatcac ttttttctaa cttagcatta tatcctacaa ttaaatttcc aatattattt
    15061 tttacacaat aatcaattat ataaaaacag gttttattta catagtcttt aacttgatta
    15121 tttctcttat tccaaacttt aaattgtttt cttgttattg cagttatatt cttttttaat
    15181 tttaaggatt ctattttatc attctgtttg tttgcccact gattcacaga ttttagcctt
    15241 tttccatcta tgataaaact atcacctaaa ttggtaacac atgtacataa attttctaaa
    15301 cccaagtcta tagctagtgc atttttttga tttgaaactt cctctgattt cggtatttca
    15361 taacaatact gaatttcaaa gaacctagct ttatgtttag gtattattct tatttcttta
    15421 atttttttct ctagtatatt ttgtggaact tttatactta ctttcccata tagtttttta
    15481 aatgctggag acataggtac atttaaaatc ccatcttctt tgattcttat ttgacctatt
    15541 attatgctaa aaaatccttc tttatctaaa tatttaggtg attttatccc tctaaagtca
    15601 tatttccctt ctttggctaa tttaattaac ccaaaaaatg acctaaacga actgtctact
    15661 tcttttaata tttgttgcgc tatattacta ttgagaagct tatagttctc attttctttg
    15721 catacatgat aattagcttc atagttaaga tgttctcctt gattgaaata atgctgtctt
    15781 acattatatg taccaacatt atataagttc ttagctaaga agcacatctc tcgtagagct
    15841 tgatattctt ttttagttaa gttttttaat tgttgtctct gagttccata gtgtatattt
    15901 tttattctgt ttgacatgaa ctcacctcct ttagaatata ctctactaga cattatatac
    15961 ggtattttta caaaacacca tatataatgt ccatttaatt actttatttt acaaaataat
    16021 ttaaatttac ttgattttat acaccttatt atttattata attgtttatt attatttttc
    16081 atacccatat aaactttttc aaaagtcata ggaagctctc ttaaacgaac tcctgtagca
    16141 ttaaatattg catttgctat agctggcgct ggtgtatgta taactatttc tcctaatgat
    16201 ttagcaccat aaggacctcc tgggtcgaaa ttctcagcaa aatctaccaa tatatttcca
    16261 acttcttttt ttgtaggaac tttatactgt aggaaactat ctgttaataa tctcccatct
    16321 ttatcaaata tagggtcttc atacattgca aaccctatac acatcatcac accaccttct
    16381 acttgtattc tagctaaagt tggatttata actgttccac aatcaggtac acatgcaaaa
    16441 tttatgacct tatattcgcc tgtattttta tctaattcta tctctgcaaa tcctgctata
    16501 aatggtttta tttttttcaa catgccaaaa gattctgttg cttccaaaac tactggtaca
    16561 tcatcactag caaatcctat tcctccaaca gattctctac ccaattcctc taatagaaca
    16621 aacttgctat tatcgttttt aacaaaaacc ctgtcttttc ccaactctaa atcttctttt
    16681 ttaaatccta gctttgactc tgcaactgaa agtaatatat cttttaattt atttgctgtc
    16741 tttattgttg catttcctgt aaccgttgtt gtacaagaag caaatgctcc tgtatcatag
    16801 ggacataaat ctgaatcacc tgtataaata gaaattctat ctacagtagt atttaaagct
    16861 tccgcagcaa tttgcgcttg aattgtatca gccccttgac ctaagtcagc aagaccagat
    16921 aatagtttat atgtgccatc ttcatccatt cttatagtga ctgttgccat atctacacgc
    16981 ggtataccag aaccatgatt tgccactgcc atacctacgg ctcttacttt gttatttcct
    17041 atatctttac atggatattt atcgtcccaa ttaattaatt tcttgccctt ttctatacat
    17101 tgtctcagct cacaacttaa tatttcgtct tcagctgctt ttccattggt atacctatct
    17161 attatatttt taattctaaa ttcaagtggg tccattccaa tcttatgtgc caattcatca
    17221 atagcactat ctattgcaaa tattccctgt gtagcaccat accctctaag tgctcctgct
    17281 ggtaacctat tagtatatac tgttctagca ttaaatctaa cagcatcaat atcattatat
    17341 attggtaagg tattgtgtcc agattcggaa gaaacagaga caccattccc accataagca
    17401 cctgtattgt ttaatgactt tagctctatt gcttttaaat ttccttcttt atctgcacca
    17461 actttaacat caaaaaacat ttcatgtcta ctattagaac ctacaaaagt ttcacttctt
    17521 gtaaatacaa attttgctgg tctaccagtt ttcatagtaa caaatgcagt aaatatatct
    17581 gttgctgcta tattctttcc tccaaatcca ccacctattc taggtttaat tactcttatt
    17641 tttgaagatg gtatacccaa tacttttcta attattctct ttacattgtg tggtgattgt
    17701 aatgacgaaa ctacaacaat tctatcattt atatctttat atgaatatga cctatgagtt
    17761 tccatcatgc aatgcgattg actttgggtt ttgtatgaag attcaaccac aaaatcactt
    17821 tctttaagct tagcttcaac atctccaaat tcaaaaaatt cttttgatac tatattattt
    17881 tttgcatcca atccaaaagg gtatggctct actatgtctt tttctggatg tataacaact
    17941 tcatttcctt ctgcttctct tgcatcaaac acaggcttta aaacctcata atctaccttt
    18001 atcattttta aggctttaag tgctgttttc tcatcttcag cagccactaa agctacttca
    18061 tctccaataa atctaactgt atcttcaagt aaaactctat cataaggtga tgcttctggt
    18121 tctgtttgac ctggcacaca atatctgacc tgtggtacat ctttatacgt ataaataccc
    18181 acaacccctg gaattttttc ggcttttgat gtatctatat tctttatctt agcatgagca
    18241 tgtggacttc taagtagttt taatgtcaaa acatctttat gcataatgag gtcttcagta
    18301 tatagaggtt ttcctgtgac aattgctgta ctatctatct ttcttatccc cttattaatc
    18361 attatacatt ccctcctcaa tagcattata catcctttta actaatgcac ttgccatatc
    18421 ctttctgtac tctttactag ctctcatatt acttccataa gtaagttcct tactagcaac
    18481 aatagatgcc ttatctatat ctttttcttt atttaatata ttactcgctt caagtgctaa
    18541 tctagctttt tgaggtcttg ccccaattgc tattttgtaa gtatcatttt cttttagcat
    18601 tgctgaattt aatacagaaa aatctcctgt gcattttctt attgagtcaa aaacagctat
    18661 cgcatctttt tttggtagta ttacttcgac caatatatcc ctacttaatt cactatccaa
    18721 aaactcactt aactctagta ttcctttatt gtataatctc accttcgctc caacaaccaa
    18781 aagcgctggt attaagtcag aaaagccata ctttgaaaat acacttgcac caattctagc
    18841 cccttgtcta aattgaacac caactatatt agaaacagcg cttgaaagta ttccactaca
    18901 gtaatttttt atagttttat caatttctaa acttctaagt gaagtatctg cacctatcaa
    18961 aatatttttt tcatcctctt ttatataatt tagatttata tcttttaaat ctatcgctgt
    19021 tcctatattt ttattactta attttataaa tccacatcca cctaaaataa cattattttt
    19081 tttagaaatt aaaattttat atgcttcttc taaactctgt ggaattgaat attcctttat
    19141 agtaaccatc ttatccccca tcattaactt attaaaacat aaaagttttt aataaatctt
    19201 ttatttatat ttataattgt agtatattta attcacatat attaaacctt tacattataa
    19261 acttttattt ttatcctcaa ccttatcact tttatttcca ggaaatttta ccatatataa
    19321 agcttgaatt attatggcta ccattgctcc tgaaactaca cttgaatctg caagtaatgt
    19381 ctctataaat tttggaaatt tttcaagaac ttgaggagct accatgaatc caataccaga
    19441 agccatagaa agacctaata tcatgctatt ttcttgatta aatccatcca tactaacaag
    19501 tcttaaacca gatgttgtaa gagttgaaaa tataacgagt gttgctcctc caaccacaca
    19561 gggaggaatt gttcttatta aattagctaa taatggcgat attcctgcca aaaataatcc
    19621 aattcctcca atagctagta caaatttact tacaaccttt gtattggaaa cgattgcaga
    19681 attttgtcca aacatcccca ttggagttgc agaaaataat gcacctattg tagagagtac
    19741 tccatttcct aaaacagcag aagaaagttc ttcatctgtt acttgtctat taagccctcc
    19801 taccgcagaa agtgtacaag cacccattat atcagctatc tcaactaaat atattattga
    19861 aaacattaca acaacttcaa gtcttatatc tagcccaaaa gcaagtggtt ttggaagcgc
    19921 aaccaaagta aactcctgaa ttgaagaaaa atttactata cccaaaatta atgataaaat
    19981 gtatccaaaa attatgctaa ctaatattga tgcatcttta aataatcctt ttccatactt
    20041 atttaatcct aatatcataa gagatacaga tattccaact ataaaattaa ttggattccc
    20101 aaaagtctca ttgcccatac ccccagctaa gttttttata gctattggaa aaagtccaag
    20161 acccatacat gcaactattg ttcctgatac agctggagta aatataaatc gtattttttt
    20221 aagaccaaaa ccaattataa ttattactat accagctatt atttgagagc caaataatac
    20281 tggtagtcca tacttacttg caacagatac cccagctcct ataaacacag ctgtagctcc
    20341 cattataact ggtattcctc ctcctaattt aaaaccttta aacaaaggta ttggatataa
    20401 ttgtaataaa gttgatagtc ctgcaaaaac taatgtggct tgaatcaata atgttgacat
    20461 cttatgatta agtccagctg catttgcaat caatatcgct ggtaaacaac tacctattac
    20521 cattgccatt aagtgttgta accccaaagg tattgcttcc tttagtggtg gtattccgtc
    20581 taattcaaat tttgatgtac tttttgcttt cataataaaa actcccgtta cataaaactt
    20641 attgaattat ataaatactt aaaaatctaa tatattaaat taatgatgtt cataaatatc
    20701 aactatactc caacatatat ttaagttttt agtcttaaaa aacagatgca ataaatttaa
    20761 ttattaacaa ataaacgtat tctttaattt tgtatacatt atataccatg ctttacaaat
    20821 ataagagtat tatagctatg aatttttaat tttttatagt aaatttaatt caatttaaat
    20881 ctttcaatct taatcattat aagttataag ttttcataag tatttacatg tttcaagttt
    20941 taaacattta cctataaacg ctactttata gatgtcactt caaatctagt gacctcatac
    21001 tttcatatga gcgtagacta tttcttcatc ttcagcatta cctgctaaga gcaacccgtt
    21061 tccactatca atcgcttata gtgtactctc tctcgagata gtcgtttgac cttcctattt
    21121 ctaggcttgg cgaccaaatg tccattttta agtacttagg ctctcaccat ataccatcct
    21181 cactattgtt tctggttttc accacattca taaaagtttc tttctatctt ttattgtagt
    21241 tgcaaggctt taggatttac tggttttaaa gttgtgtcct acatagattt ctctatgtac
    21301 ggggccaaaa gtacaattta tttaacatac tttgctttac cccctgtaaa taatattatt
    21361 tactctttca ctgtttttgt tattaaatta attaaatatc aattaatcta agcataaaat
    21421 aattatttaa tttaaactca aaatatttat gaatatttta taatataatt ctcataagac
    21481 agaaaaactt aataagctat gtatctcagt tgtaccaatg tactctcctt tactatattt
    21541 gtatctgcaa cataaaatat acaagtttct atctatttat agatatatat atctataagc
    21601 aaaatagtaa tattattttt aatagtaaaa attttattca tattactatt tataattttt
    21661 atagagcaat tttagtgcca atatttgcat atatttgtat agtataaaat ttttatgttc
    21721 tcattgataa aattttactt atttcaagcg ttttattcga ttttatcatc taaattttag
    21781 gttttatttt tataaattaa ttgtatttac ataaaaaaaa agacctaaaa acaaattttt
    21841 aacggtcttt tctcaatttt ttattttcat ttctaaaatt tataataaat agtaagaaca
    21901 ctataaattc ttttatataa aattcttagt ttgtggatga taaattagtg aattaaaata
    21961 ctactttact gattttagtt tgacaatatc actccaattt ttactagtgg ctaactctac
    22021 taaatttaag tctcttctta tttcagctat atcctctttt atagaattag tgtcaccttt
    22081 tatatatgct atgttatgtt ctatattatc atgagtagct ttatttattt cagaattatg
    22141 taataaactt cctaaaatat tattctgttc tatctgtatc tctttcattg atttatcttc
    22201 acattctaga ctatcaatct taatttcaat tccatataat ttttcatttg ctatggatac
    22261 ctcgtcctta attccattca tatcttcatt aatgttattt attttatttt gcataaagtt
    22321 tacttctgat ttaacttcgg aaacatcttc tttcattaca gttatttctt gtcttacttc
    22381 tgacatgtct tttttcatta catttatctc ttgttttacc tctgatgtat cttctttcat
    22441 tacagtcatt tcttgtctta cttcgaacat atcttctttc attatattta tctcttgtct
    22501 tacttcggac atatcttctt ttaatacatt tatctcctgt tttacttccg acatatcttc
    22561 tttcattaca gtcatttctt gtcttacttc ggatatatcc tctttcatta tatttatctc
    22621 ttgtcttacc tc
//
LOCUS       DACTZW010000069        22510 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.069, whole genome shotgun sequence.
ACCESSION   DACTZW010000069 DACTZW010000000
VERSION     DACTZW010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22510
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.069"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            111..227
                     /gene="rrf"
                     /locus_tag="JAM15_13660"
     rRNA            111..227
                     /gene="rrf"
                     /locus_tag="JAM15_13660"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            681..1751
                     /locus_tag="JAM15_13665"
     CDS             681..1751
                     /locus_tag="JAM15_13665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6799302.1"
                     /translation="MADIRLENVTKSYNKKNTVIENLNLTIEDGSFTVLVGPSGCGKS
                     TTLRMIAGLEDITSGKLKIEENDVTKTDASKRDIAMVFQNYALYPHMTVRENIEFGLK
                     NKKVEKEKREKLITEVIDVVGLREYLNVKPGNLSGGQRQRVALARAMVKNPKVFLMDE
                     PLSNLDAKLRNQMRTELIQLHQKLKSTFVYVTHDQVEAMSMADKIVIMNKGKIMQIGS
                     PKKIYQNPKNLFVAQFIGSPCMNILDIKNDIKFGFRPEKATLESINIDGKNDDVFSLF
                     GKVVTKEVLGNETIYCLSVLNREIRVKTENDIFDIGRTLRISVLEKDLYYFDKNGERI
                     EDVKVCKSIYSKIKGDIYEKAI"
     gene            1735..2604
                     /locus_tag="JAM15_13670"
     CDS             1735..2604
                     /locus_tag="JAM15_13670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAT6799303.1"
                     /translation="MKKQFNKAYLYITPAIIGTLLFIVYPIIKTISLSFKSGSLLSST
                     FENVGLNNYTELLKNPEFIQTITNTAIYTFFMVTISISLAIVLAVWLNKNSIIHNLTQ
                     SIIFTPHVISLVSVAVLWLWIMEPQYGFLNWILSTLHLPTSKWLSSESSALMSLILIG
                     IWKTLGYNILIVLSGLKSIPNYIYEASKLDNANKITNFFKVTLPLLSPTIFFLMITTT
                     TASFQVFDEISIMTQGGPVGSTNMLSYYIYESGFIYYDIGQASAASMFLLAIVMIATY
                     ANFRLLSKKVHYQ"
     gene            2648..3508
                     /locus_tag="JAM15_13675"
     CDS             2648..3508
                     /locus_tag="JAM15_13675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAT6799304.1"
                     /translation="MDIIQPIKKDKVDIKKIASKSMEILILLLLSAIFIFPFIWMLST
                     SFKNPQEMMQLPPTIIPNDIVLENYSTAWHSGPFFRYLLNSVFVTGSVLIVQFLVMVP
                     AAYAFSKIKFKGEKMLFGLLLVGLMIPPQVTFLPVYMMMSKFGFINTYVPLIIPFMTS
                     SFGIFLLRQNFMQISDEIIEAAKLDNASDLKIMFRIMVPMAKPAVITFILFNFIYHWN
                     NYFWPLVMTNTDAIRTLPIGVALLKSSEGITAWNVIMAGNIILILPIILVYIFANKKV
                     KEAFMYSGIK"
     gene            3539..4843
                     /locus_tag="JAM15_13680"
     CDS             3539..4843
                     /locus_tag="JAM15_13680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAT6799305.1"
                     /translation="MKLKRKLATGLAITLLLGSLVGCSNSNDANASKGEKTDSNITKI
                     DFWAPLGGTNGETAQKMVDQFNSEHKDVQVNMLKQKDYYENATKLQAALTSKDQPDVT
                     LLEITQTGTFASAGALVDMSKYFDKTYQERFFSGLLTNSYYEDKFVGMPFNRSTPILY
                     INRDMATKAGLDPSGPKSWEELKDYASKMTNKSEDTYGFETPIDIWFYEAMVMQSGGE
                     ITNGKKVAFNNEAGQAPVKFWQDMMKAGIMKMPPGEDYNAWDVAKQDFVNGKVGMIFT
                     STADLAGLMQQTEGKFEISTAFLPKNQKYATPTGGANLVMLEGGTDKEKEASAEFIEW
                     MTQTDKIVQFSSSTGYLPTTEDATNSEKLQTLYKEKPQYKVATDQLQYAVALPMLNGY
                     KEATDKLMDEIKKGLTDLNANPKDVVSKGTSAMQAVIDKTNK"
     gene            4906..6168
                     /locus_tag="JAM15_13685"
     CDS             4906..6168
                     /locus_tag="JAM15_13685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HAT6799306.1"
                     /translation="MTKVIVLSVDSLFEKDLEFVKNLPNFKSILENCSIVKNINCVYP
                     TLTYPCHTSMVTGVYPKKHGIYHNEKFDPNKENKDWYWYSKDIKVKTIIDVAKENNLT
                     TSSVLWPVMGANPNIDYNIAEIWAPSREDDPRETFERSSSKVIMDGIYNRHCHYIDWK
                     LEPNMDLFGVNCSVDIIKEYKPDLMLIHLATLDHTRHNYGLFNDEVDKALKMNDKWLG
                     DIIQATKDAGTYKDTNFIILGDHGHLRVDKVINPNVLLKSNGFIKVENGEVKDFDAYV
                     NSSGISAQIIVNNLDRLTELRELLEEFKEELFIENIFTKEEASNLGLEGDFEMVIEGL
                     EGISFGNDFEGSIIKDSDIKDYKFAVATHGHLPTKGNRPPFIAFGPNIKGGVVIEEGD
                     LRAHAATILKMFDLKLDGVEKEAFDFIM"
     gene            6355..8325
                     /gene="uvrB"
                     /locus_tag="JAM15_13690"
     CDS             6355..8325
                     /gene="uvrB"
                     /locus_tag="JAM15_13690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HAT6799307.1"
                     /translation="MDFKIKSDFKPTGDQPEAIKSIVDSINRNEKFSTLLGVTGSGKT
                     FTMANIIQQVKKPTLIMAHNKTLAAQLYSEFKEFFPDNAVEYFVSYYDYYQPEAYVAH
                     SDTYIEKDASINDEIDKLRHSATASILERRDTIIISSVSCIYGLGDPKDYKELMLSIR
                     PGMQRDRDDVIKRLIEIQYERNDINFTRGTFRVRGDILEIFPASNDEKAIRIEFFGDE
                     VDRITEIDYVTGKIVGTRNHVVIFPASHYVTTPERIEKAIVEIENELQEQIKFFKEND
                     RLLEAQRIEQRTKYDIEMLKEIGFCQGIENYSRHITGRSEGERPYTLMDFFPDDYLII
                     VDEAHVTIPQVRGMYAGDRSRKTSLIENGFRLPSALDNRPLNFQEFEGNINQMLFVSA
                     TPGPYEIQHSETIAEQIIRPTGLLDPIVEVRPINNQIDDLVGEITKTIEKNERVLITT
                     LTKKMSEDLTNYLKEIGIKVKYLHSDIVTLERTEIIRDLRLGKFDVLVGINLLREGLD
                     IPEVSLIAILDADKEGFLRSETALIQTIGRAARNENGRVIMYADRITDSMQNAIDETK
                     RRRDIQNLYNEEHNIIPKTIQKNIRDSIEATKVAEEEVVYGISDTDDKDEIRANIDKL
                     KSEMMEAAQNLQFERAAELRDKVKQLEEKLEK"
     gene            8344..11169
                     /gene="uvrA"
                     /locus_tag="JAM15_13695"
     CDS             8344..11169
                     /gene="uvrA"
                     /locus_tag="JAM15_13695"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HAT6799308.1"
                     /translation="MEDKIIIRGAKEHNLKNIDLELPRDKFIVFTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGQMEKPNVEYIEGLSPAISIDQKTTSKNPRSTVGTV
                     TEIYDYLRLLFARVGDVYCPTCGEKISQMTIQEIVDKMLDFPDRTKLQILSPIVRGQK
                     GTHKKVFDNIKKEGFVRVRVNGENYEVSDDIILNKNQKHNIEVVVDRIVIKDGIESRL
                     ADSIETAVKLSDGLVIAQIIDGEEILFSTKFACPEHGIGIEELSPRMFSFNAPFGACD
                     VCNGLGESKEVDPELVVPNKDLSIKQGAVAAWGSTGVNDDTYYSKMIKSLAEHFNVSL
                     TTPFKDLPDDFVEELLYGKDNIIVEFTYESKFGGTRNYKSYFEGVIVNLERRYRETNS
                     DYMRDKIEEYMAERPCPKCKGMRLKKEVLSVLVDGKNIMEVTNLSVNELIDFMENINL
                     TEKQRFIAHEIIKEIKGRAMFLRDVGLDYLNLSRKAGTLSGGEAQRIRLATQIGSALV
                     GVLYVLDEPSIGLHQRDNDRLITTLRHLTDLGNTLIVVEHDEDTMREADYVIDIGPGA
                     GIHGGEIVAQGTLDEIIENENSITGQYLSGKKQILLPETTREGNGSFIEIVKASENNL
                     KNIDVKFPLGKFTCITGVSGSGKSTLINDILYKGVASKVNRLKQRAGKHKEIKGIESI
                     DKVINIDQSPIGRTPRSNPATYTGVFDFIRDIFASTNEAKARGYKKGRFSFNVKGGRC
                     EACKGDGIIKIEMHFLPDVYVPCEICKGERYNRETLQVKYKDKTISDILDMNVEEAVE
                     FFENIPNIKRKLETLMDVGLSYIKLGQPSTQLSGGEAQRIKLATELSKRPTGKTLYIL
                     DEPTTGLHMADVDKLIQVLQRLADTGNTIIVIEHNLDVIKTCDYVIDLGPEGGDKGGT
                     IVATGTPKEVSKVDGSYTGQFLKKYFS"
     gene            11428..13245
                     /gene="uvrC"
                     /locus_tag="JAM15_13700"
     CDS             11428..13245
                     /gene="uvrC"
                     /locus_tag="JAM15_13700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HAT6799309.1"
                     /translation="MFDIQEHLKKLPSEPGVYLMKDKYDHIIYVGKAISLKNRVRQYF
                     QSSKNHTSKVKSMVKNIYKFEYIITDSELEALILECNLIKRYRPKYNVVLRDDKTYPY
                     IKVTTNEDYPRILKVRRVLKDKAKYFGPYTNITAVNDTLELISSTYPIRSCKIDIDKA
                     IKNKTRPCLNLHINKCLGPCTGNVSKEEYGKMIEEIIMCLSGKEEKLMELLKEKMNES
                     SMNFRFEEAAVYRDKIKSLEEMIQKQKIDATVSDLNQDVVAMARAHNEACVQVFFIRN
                     GKIVGREHFILEGVMDSPRASILSSFVKQFYNEQEYIPKELIIEDEIEDSSILEEWLS
                     SKKGQKVTIRVPQKGEKKSLVEMVRKNAVEYLEKFSDMNKRKYEKSIGALEELKQILN
                     LEKLPIRIEAYDISNIQGVDSIGSMVVYTNAKKDKKEYRRYKIKTVIGPNDYDSMAEI
                     VDRRLKHGNLPDLILLDGGKGQVSAVKKVLELNDVDIPLWGMYKDDKHRTKGLICKEK
                     EIELDKTTNLYRFIASIQEEVHNYAITYHRSLRNKALTKSILDDIQGIGEKRKKSLLN
                     HFKDVEAIKKATMEEILEVDGMNKSIADNVYNFFRKEEN"
     gene            13245..14174
                     /locus_tag="JAM15_13705"
     CDS             13245..14174
                     /locus_tag="JAM15_13705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HAT6799310.1"
                     /translation="METSNKVSIREIIKELKLKVVYMPDDVDYYVYSQDINRPGLQFA
                     GYFDYFAYERIQIVGKTEYNFFGLMDSHIREEVLDRFFSYEIPALIISRDLEIKPDVI
                     EKAKKYKRILLSTNRNTTRLINRLSNYLDNKLAPHTTIHGVLVDIYGIGVLIKGESSI
                     GKSETALELIQRGNRLVADDAVEIRKLDESMLVGQSPELIRHFLEIRGIGIIDVRSLY
                     GVGAIKNSKMIDLVVHLEAWDETKYYDRLGLDKEYEEILGVNVEKLVVPVKPGRNTAM
                     ILEVAAMNFRQRGMGYDAAQEFTKKLSKLIDTK"
     gene            14388..16184
                     /locus_tag="JAM15_13710"
     CDS             14388..16184
                     /locus_tag="JAM15_13710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate oxidoreductase"
                     /protein_id="HAT6799311.1"
                     /translation="MGIEYFSKLLESSTEKELLLSKKSNNISTARLISFLIVIAGLAI
                     GFYNKNIVGIFVGVLSIIIFIALLVIHSKVKEEETYFKSKSEVLNKYIKRFGDGWKEF
                     KIDGKEYLKDENSQAKDLDLFGRASLYQYICVANTSYGKNFLAKYLWNENPDENVILE
                     RQRAIKELLSKDDFSIHIQILSNIIGKEQKNNSDSSIESFIEYGENKNVYIPKWMHIF
                     TWGLPTATILSFIFCMLGFLPVLPVFLLFIIQLGFSGFGYPRLMQTLSPLFSFSRSIQ
                     VYEKMFEVLEKETFESAYLKELQDKLSKGSGVSRGVKQLNSIGNAVNLRYNQILYIIA
                     CGVLMWNYHCAEALERWKGIYGNQIRDWFESIGEFEALISLTVISHVKENTCFPVIKY
                     EDTPRLKVEEVYHPLIAEKSVIANSIQLNSQTCIITGSNMSGKTTFLRSIGVNLVLAY
                     AGAPVCAKSFDATCMAIFTSMRIQDDVSQGISTFYAEILRIKSMIQYSLKELPMLVLV
                     DEIFKGTNSADRIIGASEAVKKLSKPWVISMVTTHDFELCDLSGSGDVEVVNYHFSEY
                     YVDDKIHFDYKIKDGRCKTTNAKQLMRMAGIL"
     gene            complement(16324..18105)
                     /locus_tag="JAM15_13715"
     CDS             complement(16324..18105)
                     /locus_tag="JAM15_13715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:ubiquinone oxidoreductase"
                     /protein_id="HAT6799312.1"
                     /translation="MSLVNLTINGKHVSAPSGTSILDAAKLINIKIHNLCHLHMNEID
                     KLDTCASCRVCMVETERGLVPACGTVIKEGMKVQTNSAKALNARRTIVELLLSDHPQD
                     CFVCEKNGDCELQTIAADLGVRKIRYQGSKSFAGKDTSTKSLVKDHSKCILCRRCETV
                     CNDIQTVGALSGVNRGFNTLVSTFFNSDMVETECTFCGQCISVCPTGALTEVDNVPKL
                     WDVLNKKEKTIVVQVAPAVRVAIGEEFGLEPGSISTGKMVAALKALGFEHVFDTNFGA
                     DFTIMEEATEFIERIQKGENLPILTSCCPAWVNFLEHNYPDKLNLASSCKSPQGMFGS
                     IAKNYYAPKILGINPEELYVVSVMPCVAKKYEASREELSESGILDVDLSITTRELAKM
                     IKEAAIDLPNLQDQDFDNPLGKSTGAASIFGASGGVLEAALRTSYEKITNKTLDNVNF
                     TNVRGLKGIREASIDVDGTTVNVCIVNTLKNARKIMDKVRSGECKYHIIEVMACPGGC
                     VGGAGQPYHHGNTEIVDRRANALYEIDRNKAIRKSHENPDLQAIYKDFFGEPNSDVAH
                     KYLHTHYFDKSCVYGECPQECACEEAK"
     gene            complement(18128..20014)
                     /locus_tag="JAM15_13720"
     CDS             complement(18128..20014)
                     /locus_tag="JAM15_13720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoF"
                     /protein_id="HAT6799313.1"
                     /translation="MRKVNSFDELKVLADELKPNLSLRKNYSKENVLRRELLVCCDTG
                     CTSSNSLEIVSELENEIKKSGIQDKVSVRLTGCFGFCAQGPIVKVYPDNVFYVKVEPS
                     DAEKIVQSHLIRNTVVEELLYEEESLSKKVEEQEEMSFYKKQLRIALKNCGLIDPDSI
                     EEYIANDGYLALGKCLTSLTPQEVIAEVKTSGLRGRGGAGFPTGSKWEAASKNPAGPT
                     DKKFVVCNADEGDPGAFMDRSVLEGDPHSVLEAMAICGYAIGSDTGYIYIRAEYPKSI
                     ERLKVAIAQAEKYGLLGENILGTGFNFKLELKYGAGAFVCGEGTALMHSIEGRRGEPR
                     MKTYSSSKSGLWKSPTCLNNVETFANIPAIILKGGDWFANLGTEDSSGTKVFALGGKV
                     ENVGLVEVPMGTTLRDIVFEIGGGIPEGKKFKAVQTGGPSGGCIPTEHLDTPIDFGSL
                     SSIGSMMGSGGMLVLDESDCMVDIAKFFLEFTVEESCGKCTPCRIGTTRLLEILTKIT
                     EGNGTLQDLDDLENLAETIQTASLCGLGKAAPNPVLSTLQYFKDEYIAHVVDKKCPAG
                     KCQNLLSYFITDDCKGCTKCSRVCPAGCITGSVKEQHTIDTSKCLKCGACIDNCTFNA
                     IIKK"
     gene            complement(20031..20528)
                     /locus_tag="JAM15_13725"
     CDS             complement(20031..20528)
                     /locus_tag="JAM15_13725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase subunit E"
                     /protein_id="HAT6799314.1"
                     /translation="MCDFISHNKQLFDELDIFIDSLATKEGALIQVLHEAQGIFGYLP
                     KEVQLHVARKLGVAPAKVYGVVTFYSYFTTEPVGKYKISVCLGTVCFVKGADKILSAF
                     EKQLGIKVGETTSDFKFSLEGLRCLGACGLAPVVTVNGKVYGKVKPDQVSEILDTYRE
                     LELNC"
     gene            complement(20846..22327)
                     /gene="cls"
                     /locus_tag="JAM15_13730"
     CDS             complement(20846..22327)
                     /gene="cls"
                     /locus_tag="JAM15_13730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HAT6799315.1"
                     /translation="MFDISFFEMSIYEIAVTTIYIINFMVILNLIFREKRNINTTLTW
                     LLILVLIPALGFILYIAFGRNISKNNMFRLKEKDDKIIKSNILDTQVKLQSTSEIDSD
                     IHQHKDMIYALANSNNAHYTNNNDVWIYAESSQFFNSLLEELKKAKKYINIQFYIFKD
                     DKIGTEIIDILIDKAKEGVEVRLLFDAVGGRTLKNSTLSRLKESGVKVGSFFPSFLKI
                     VNFNLNYRNHRKIVVIDGKVGFVGGYNVGDEYLGRNPKFGLWRDTHTKLTGDCVIDLN
                     MRFILDWRYTTKEDLDLEKYFIEEDTNSNHPSENIGIQIVSSGPDISELDEIKYGYLK
                     MIQKARKYIYIQSPYLILDSTFIDTLKIACLSGVDVRVMIPSKPDHPFVYWASYSYAG
                     ELLKFGAKIYTYGQNAFLHAKTIVIDDSICSIGTANMDIRSFELNFEVNAFMYSSKKA
                     LEQRIIFENDILNSKEITLDIYNSRSTYIKIKESISRLLSAVL"
BASE COUNT         8675 a         3004 c         3750 g         7081 t
ORIGIN      
        1 ttcattaaga tatatgtgta gtttttagag tgttaactct aaagaaacta gtattactag
       61 gttctataaa cttattaaaa acttaataga aatattaagc ataaagatta tgtggttaca
      121 atagcagaga ggatacacct gttcccattc cgaacacaga agttaagttc tctagcgctg
      181 atggtacttg gtgggaaact gcctgggaga gtaggacgta gccacgtaat ttttttgggt
      241 aaatttataa aaattaaaaa agttttattt tttatgttta aaccttgtaa atttgggaca
      301 taatataatt gtaaaactta atatagcaaa aataaattac tcaatctccc ccacttaaag
      361 acctctatcc cccatagagg tcttttttat tttcaaacca aattatataa aaaataaata
      421 gttttatatg actcttcata aattaaaatc acattgtgat agcaaaccat gaatatgaaa
      481 aatatagaaa attatagcta acataagctg tatatcatct taacttcagt atatttaaca
      541 aaaaatgttt ataatttaac ctttatttta ataagtttac tatatattca ctttgtctta
      601 atatatcctt tacaaattaa gagtattatt aatctataag taaatcgtag aattaaatta
      661 aatattttgg gaggataaaa atggcagata taagactaga aaatgtaaca aaatcttata
      721 ataaaaaaaa tacagttata gaaaatttaa atcttactat agaagatggt tcttttacag
      781 tattggtagg tccaagtgga tgtggtaaat ctactacatt aagaatgatt gcaggtcttg
      841 aagatataac ttcaggcaag ttaaaaattg aagaaaatga cgttacaaaa acggatgcta
      901 gtaaaaggga tatagctatg gtatttcaaa attatgcatt atatccacat atgactgtta
      961 gagaaaacat agaatttggt cttaaaaaca aaaaagtaga aaaagaaaaa agagaaaaac
     1021 ttataacaga agttattgat gtagtaggat tgagagaata tttaaatgtg aaaccaggca
     1081 acttatctgg aggtcaaaga caaagagtgg cacttgctag agctatggtt aaaaatccaa
     1141 aggtattttt aatggatgaa ccattgtcaa atttagatgc taaattaaga aatcaaatga
     1201 gaacagaatt aatacaatta catcaaaaac taaagtctac atttgtttat gtaactcatg
     1261 accaggttga ggcaatgtcg atggcagata agatagttat aatgaacaaa ggaaagataa
     1321 tgcaaatagg ttctccaaag aagatatatc aaaatcctaa aaatttattt gtagctcaat
     1381 ttatagggag tccttgtatg aacatactag atataaaaaa tgatattaaa tttggattca
     1441 gaccagaaaa agcaacacta gagagtataa acatagatgg aaaaaatgat gatgtattta
     1501 gtctatttgg aaaagttgta actaaagaag tgttgggaaa tgaaactata tattgtttat
     1561 ctgttcttaa tagagagata agagtcaaaa cggaaaatga tatatttgat attggaagaa
     1621 ctttaagaat aagtgtatta gaaaaagatt tatattattt tgataaaaat ggagaaagaa
     1681 tagaagatgt aaaagtatgt aaaagtatat attctaaaat taaaggagat atttatgaaa
     1741 aagcaattta ataaagcata tttatatata acacctgcta ttataggaac tttattgttt
     1801 atagtctatc caataattaa gacgatatct ctaagcttca aatctggtag tcttcttagt
     1861 tcaacctttg aaaatgtagg cttaaacaat tatacagaac ttttaaagaa tccagagttt
     1921 atacaaacta taacgaacac tgcaatttat acttttttta tggtgactat atctatatca
     1981 ctagccatag tacttgctgt ttggctaaat aaaaattcta taatacacaa tttaacgcaa
     2041 agtataatct ttacaccaca tgtaatttca ctagtatctg tagctgtatt gtggctttgg
     2101 attatggagc cacaatatgg ctttttaaac tggatactat cgacattaca tttaccaaca
     2161 tcaaagtggc tttcaagtga aagttcagct ttaatgtcac taattctaat aggaatatgg
     2221 aagactcttg gatacaatat cttaatagta ttatcaggtc ttaaatccat accaaactat
     2281 atatatgaag catctaaatt agataatgca aacaaaataa cgaatttctt taaagtgaca
     2341 ttgccgctat tatcaccaac aatatttttt cttatgataa caacaacaac tgcatctttt
     2401 caagtatttg atgagataag tataatgaca caaggtgggc cagtgggttc aactaacatg
     2461 ttatcttatt atatatatga gtctggattt atatactatg acatagggca agcgagtgca
     2521 gcgagtatgt ttttgttagc tatagttatg attgctacat atgctaactt tagactctta
     2581 tcaaagaaag ttcattatca ataaagaaaa agtagatatt ataagattta tccaaaagga
     2641 ggagacaatg gatattatac aacctatcaa aaaagacaaa gttgatataa aaaaaatagc
     2701 atcaaaatca atggaaatat taattctatt acttttatct gcaatattta tattcccttt
     2761 tatatggatg ctatcgacat cctttaaaaa tccacaagaa atgatgcaat taccacctac
     2821 tattatacca aatgatatag tgttagaaaa ttatagtaca gcatggcatt caggtccatt
     2881 ttttagatat ttactaaaca gtgtatttgt aacaggaagt gttttaattg tacaattttt
     2941 agttatggtt ccagcagcat atgcattttc taagattaaa tttaaaggtg aaaaaatgtt
     3001 atttgggctt ttgcttgtag gacttatgat tccaccacaa gtaacttttc taccagtcta
     3061 tatgatgatg agtaagtttg gatttataaa tacttatgtt ccacttataa ttccatttat
     3121 gacatcttca tttgggatat ttctgcttag acagaatttt atgcagattt cagatgaaat
     3181 tattgaagca gctaaactag ataatgcttc tgacttaaaa ataatgttta gaataatggt
     3241 tcctatggca aaaccagcag taataacatt tatattattt aattttatat accattggaa
     3301 taattatttc tggcccttag taatgacaaa tacagatgca ataagaactt taccaatagg
     3361 agttgcgctc cttaaatctt cagaaggaat tactgcatgg aatgtaataa tggcaggaaa
     3421 tataattcta attttaccaa taattcttgt ttatatattt gcgaataaaa aagtaaaaga
     3481 agcttttatg tattcaggaa taaaataaaa aattaaagac taaatttgga ggatgaaaat
     3541 gaagcttaaa agaaaattag caacaggatt agcaataaca ttattattag gttctttagt
     3601 tgggtgttca aattctaatg atgcaaatgc atctaaagga gaaaagactg atagcaatat
     3661 tacgaagata gatttctggg ctcctttagg tggaactaat ggagaaactg ctcaaaaaat
     3721 ggttgaccaa tttaatagtg aacataagga tgtacaagta aatatgttaa aacagaaaga
     3781 ttactatgaa aatgcaacaa aactacaggc agccttaaca tctaaagacc aaccagatgt
     3841 aacattatta gaaataactc aaacaggtac attcgcatca gcaggtgctt tagtagatat
     3901 gagtaaatat tttgataaaa catatcaaga aagattcttt tctggtcttt taacaaattc
     3961 atattatgag gataagtttg ttggtatgcc atttaataga agtacaccaa tattatacat
     4021 aaatagagat atggcaacta aagcaggtct tgacccttca ggtccaaaat catgggaaga
     4081 gcttaaggat tacgctagta aaatgacaaa taaatcagaa gatacttatg gttttgaaac
     4141 accaatagat atttggttct atgaagctat ggtaatgcaa agtggaggag aaataactaa
     4201 tggtaaaaaa gtagcattta ataatgaggc aggacaagca ccagttaaat tctggcaaga
     4261 tatgatgaaa gctggaataa tgaaaatgcc tcctggagaa gattataatg cctgggacgt
     4321 agcaaaacaa gattttgtaa atggtaaagt aggtatgata tttacatcaa cagcagattt
     4381 agcaggactt atgcaacaaa cagaaggtaa gtttgaaata tcaacagcat tcctaccaaa
     4441 aaatcaaaaa tacgcaactc ctacaggtgg agctaatcta gttatgcttg aaggtggaac
     4501 agataaagaa aaagaagcaa gtgcagaatt tatagaatgg atgacacaaa cagataaaat
     4561 cgttcagttt agttcatcaa caggatactt accaacaact gaagatgcaa caaactcaga
     4621 aaagttacaa acattatata aagaaaaacc tcaatataag gttgcaactg accaattaca
     4681 atatgctgtt gcacttccaa tgttaaatgg atacaaggaa gcaactgata agctaatgga
     4741 tgagattaaa aaggggctta ctgatttaaa tgcaaatcca aaagatgtag taagcaaagg
     4801 aacttctgca atgcaagcag taatagataa aacaaataaa taattatata gacttgtaag
     4861 ttgattaaaa gtattcaata atatataaat gaagaggtaa tgtaaatgac aaaggttata
     4921 gtattatcag tagattcttt atttgaaaaa gacttggaat ttgtaaaaaa tctaccaaac
     4981 tttaaatcta tactagaaaa ttgctccata gtaaaaaata taaattgtgt ttatcccact
     5041 ctgacatatc cgtgtcatac tagtatggtt acaggagtat atcctaaaaa acatggtata
     5101 tatcataatg aaaaatttga cccaaataaa gaaaataaag actggtactg gtattcaaag
     5161 gacataaaag taaaaactat tatagatgta gcaaaagaaa ataatctaac tacctctagt
     5221 gtattatggc ctgtaatggg agcaaatcca aatatagatt ataatattgc agaaatatgg
     5281 gctcctagta gagaagatga cccaagagaa acttttgaac gaagctccag taaggttata
     5341 atggacggta tttacaatag acattgtcat tatattgatt ggaaattaga acccaacatg
     5401 gatttatttg gagtaaactg ttcagtagat ataataaagg aatataaacc agatttaatg
     5461 ctaatacatt tagctacatt ggaccataca cgacataatt atggcttatt taatgacgaa
     5521 gtagataaag cattaaaaat gaatgataaa tggctaggag atattattca ggctacaaag
     5581 gatgcaggta catacaaaga tacaaatttt ataatacttg gggaccatgg tcatcttaga
     5641 gttgataaag ttataaatcc aaatgtcttg cttaaatcaa atggatttat aaaagttgaa
     5701 aatggagaag ttaaggattt tgatgcctat gtaaattctt ctggaatatc agctcaaata
     5761 atagtaaata acttagatag gttaacagaa ttaagagaac tgcttgaaga atttaaagaa
     5821 gaattattca tagagaatat ttttaccaaa gaggaagcat ctaaccttgg tcttgaaggt
     5881 gattttgaaa tggtgattga aggtcttgaa ggaatttcat ttggaaatga tttcgaagga
     5941 agtattataa aagattcaga tataaaagat tacaagtttg ctgttgcgac acatggtcat
     6001 ttacctacta aaggtaatag acctccattt atagcttttg gaccaaatat taaaggtggt
     6061 gtggttatag aagaaggaga cctgagagca catgcagcaa ctatattaaa aatgtttgat
     6121 ttaaaattag atggagttga aaaagaagca tttgatttta ttatgtaagt tgaataaagt
     6181 atttattttc catgaattat agacttctat tgcaaagata gaagtctttt tttatgtttt
     6241 agatttaagt aaaatttaaa tgggtaaaat atttaaaata acttaaacaa ttttataaag
     6301 gtatgatata ataatacatg tcaggaacta atgttcgaaa aaaggagtga tactatggat
     6361 tttaaaataa aatcagactt caaacctaca ggtgaccaac cagaagctat taaatcaata
     6421 gtggattcta taaatagaaa tgagaaattt tcgacattat taggtgtaac gggttcagga
     6481 aaaacattca caatggcaaa tatcattcaa caagttaaga aacctaccct aataatggct
     6541 cataataaaa ctctagcagc acaactttac agtgagttta aagaattttt cccagacaat
     6601 gcagttgaat actttgtaag ttactatgat tattatcaac cagaagcata tgtagctcac
     6661 agtgacactt atatagaaaa agatgcaagc ataaatgatg aaatagataa acttcgacat
     6721 tctgctacag catctatttt agagagaaga gatactataa taatatcatc tgtatcttgt
     6781 atatatggac ttggtgaccc aaaagactat aaagaactta tgttatctat aagaccaggt
     6841 atgcaaagag acagagatga tgtaataaaa aggttaatag agatacaata cgaaagaaat
     6901 gacataaact ttacacgagg tacctttaga gttagaggag atatactaga aatattccca
     6961 gctagtaatg atgaaaaagc aataagaata gaattttttg gtgatgaggt agatagaata
     7021 acagaaattg attatgtaac agggaagatt gttggtacta gaaatcatgt tgttatattc
     7081 ccagcatctc actatgtaac aacgccagaa agaattgaaa aggcaattgt agaaatagaa
     7141 aacgagcttc aagaacaaat taaatttttc aaggaaaatg ataggctatt agaagcacaa
     7201 agaattgaac aaagaactaa gtatgatata gaaatgttaa aggaaatagg attttgtcag
     7261 gggatagaga actattctag acatattaca ggaaggtcag aaggagaaag accatatact
     7321 ttaatggatt tcttcccaga tgattatttg ataattgtag atgaggcaca tgtcactata
     7381 ccacaagtaa gaggtatgta tgcaggagac aggtctagaa aaacatcact tatagagaat
     7441 ggttttagat taccttctgc acttgacaat agaccattaa attttcaaga atttgaagga
     7501 aatataaatc aaatgttgtt tgtaagtgct acaccaggac cttatgaaat tcaacactca
     7561 gagacaatag cagaacagat aataagacca actggccttt tagacccaat tgtagaagta
     7621 agacctataa ataatcaaat agatgatttg gtaggagaaa taactaaaac tatagaaaaa
     7681 aatgaaagag tgcttataac cactttaact aaaaaaatga gtgaggactt gactaactat
     7741 cttaaagaaa tagggataaa agttaaatat ttacactcag atatagttac attagaaaga
     7801 acagaaataa taagagattt aagattaggg aagtttgatg tacttgtagg aataaactta
     7861 cttagagaag gattggatat accagaagtt tcacttatag caattttaga tgcagacaaa
     7921 gaaggtttct tacgttccga aacagcttta atacagacta ttggacgtgc agctagaaat
     7981 gaaaatggaa gagtaattat gtatgcagac aggataactg actcaatgca aaatgctatt
     8041 gatgaaacaa agagaagaag agatatacaa aatttatata atgaagagca caatataatt
     8101 cctaaaacta tacagaaaaa tataagagat agtatagaag ctactaaggt tgcagaggaa
     8161 gaagttgtat atggaatatc tgatacagat gataaagacg aaataagagc taatatagat
     8221 aaattaaaat cagagatgat ggaagctgct caaaacttac aatttgaaag agcagcagaa
     8281 cttagagata aagtgaaaca attagaagaa aaattggaaa aatagaaagg taaaaacaac
     8341 attatggaag ataaaattat aataagagga gcaaaagaac ataatttaaa aaatatagat
     8401 ttagaattac caagagataa atttattgtt tttacaggtt tgtcagggtc tgggaagtct
     8461 tctttggcat ttgatacaat atatgcagaa gggcagagaa gatatgtaga aagtctatct
     8521 gcttatgcaa gacaattttt aggtcagatg gaaaagccaa atgtagaata tatagagggt
     8581 ttatcaccag ctatctcaat tgaccagaag actacctcaa aaaacccacg ttctactgtt
     8641 ggaacagtaa cagaaatata tgattatttg agactattat ttgcaagagt aggagatgtg
     8701 tattgcccta catgtggtga aaaaataagt cagatgacta ttcaagaaat agttgataaa
     8761 atgctagatt ttccagatag aacgaaatta caaattcttt caccaattgt tagaggacaa
     8821 aaaggtacac ataaaaaagt ctttgataat atcaaaaaag aaggatttgt aagagttaga
     8881 gttaatggtg agaactatga agttagtgat gatataatct taaataaaaa tcaaaaacat
     8941 aatatagaag ttgtagtgga cagaatagta attaaagatg gaatagaatc aagactagca
     9001 gattcaattg aaactgcagt taagctatct gatggtcttg taatagccca aataatagat
     9061 ggagaagaaa ttcttttttc aactaaattt gcatgcccag aacatggaat tggcatagaa
     9121 gaattatctc caaggatgtt ttcatttaat gctccctttg gtgcttgtga tgtttgtaat
     9181 ggtcttgggg aaagtaaaga agttgaccca gaattagtag taccaaacaa agatttatca
     9241 ataaaacaag gtgcagtggc agcatggggt tcaacaggtg ttaatgatga cacttattac
     9301 agtaaaatga taaaaagttt agcagagcat tttaatgtat ctttgacaac accgtttaaa
     9361 gatttaccag atgattttgt ggaggaatta ctttatggta aagataatat aattgtagag
     9421 tttacttatg agtcaaaatt tggaggaact agaaattata aatcatactt tgaaggtgta
     9481 atagtaaact tagagagaag atatagagaa actaattcag attacatgag agataagatt
     9541 gaagaataca tggcagagag accatgtcca aagtgtaaag ggatgagact taaaaaggaa
     9601 gttttatctg ttttagttga tggaaaaaat ataatggaag ttacaaactt atctgtaaat
     9661 gaattgattg actttatgga aaatataaat cttacagaaa aacagagatt tatagctcat
     9721 gagattataa aagagataaa aggaagagct atgttcttaa gagatgtagg tcttgattat
     9781 ttaaatttat caagaaaagc tggaacttta tcaggaggag aagcgcaacg tataagatta
     9841 gctactcaaa taggttctgc attggttgga gttttatatg tacttgatga gccaagtata
     9901 gggcttcacc aaagagataa tgataggctt ataactactc ttagacatct aacagattta
     9961 ggaaatacct taatcgttgt agagcatgat gaagacacaa tgagagaagc tgattatgtt
    10021 atagacattg gtccaggtgc aggtatacat ggtggtgaaa tagttgcaca gggtacttta
    10081 gatgaaataa ttgaaaatga gaactcaata acgggtcaat atttaagtgg taaaaaacaa
    10141 atattgcttc ctgagactac tagagaagga aatggaagtt ttatagaaat agttaaagca
    10201 tcagaaaata atctgaaaaa tattgatgta aagttcccat taggtaagtt tacatgcata
    10261 acaggtgttt caggttctgg aaaaagtaca ttaataaacg atatacttta caaaggtgtt
    10321 gcaagtaaag tgaatagact taagcaaaga gctggtaagc ataaggagat aaaaggaatt
    10381 gaaagtatag ataaagttat aaatatagac caaagtccta ttggaagaac acctcgttca
    10441 aatcctgcta cttatacagg tgtatttgat tttataagag atatttttgc atctactaat
    10501 gaagctaaag caagaggtta taaaaaaggt agatttagtt ttaatgtaaa aggtggtaga
    10561 tgtgaagctt gtaagggtga tggaataata aaaatagaaa tgcatttctt accagatgta
    10621 tatgttcctt gtgaaatttg taaaggtgaa agatacaata gagaaacatt gcaagtaaaa
    10681 tacaaagata aaactatatc tgatatatta gatatgaatg tggaagaagc tgttgagttt
    10741 ttcgaaaata taccaaatat aaaaagaaaa ttagaaactt taatggatgt aggactttca
    10801 tatattaaat taggacagcc ttcaactcaa ttatcaggag gagaagcaca acgtataaaa
    10861 ttagctactg aacttagtaa aagaccaaca ggaaagactt tgtatatatt agatgaacct
    10921 actactggac ttcatatggc agatgtagac aagctaatcc aagtattaca aagactagca
    10981 gatacaggaa atacaattat agtcatagaa cataatttag atgttataaa gacttgtgat
    11041 tatgtaatag acttaggacc agaaggcgga gataagggtg gaactatagt tgcaactgga
    11101 acaccaaaag aagtatctaa agttgatggt tcttatacag gtcaattctt aaagaaatat
    11161 ttttcttaag ttatataaat tgtgaaaaat tttagagcag atatacgata aactgttttg
    11221 ttataagtaa attagtcaaa tataagttgt aaatagtaat acaaagtaaa gtccatatta
    11281 ctcttcatgg ttaaaattgt tttcaaatca attatagaag ggaatatgga ctttaacttg
    11341 tctaaagcac tggaaattgt ataacttttt aaaattcata ttttagggta taattttagt
    11401 ataaaattta atgttttgga gggcgagatg tttgatatac aagagcattt aaaaaaatta
    11461 ccttctgagc ccggagtata tttaatgaaa gacaaatacg accatataat atatgtggga
    11521 aaagccatat ctctaaaaaa tagggtaagg cagtattttc aatcttcaaa aaaccataca
    11581 tctaaagtaa aatctatggt taagaatata tataagtttg agtatattat aacggattca
    11641 gagttagagg cattaatact tgaatgtaat ttaataaaaa ggtacagacc aaagtataat
    11701 gtagtgctta gagatgataa aacttatcca tatataaaag taactacgaa tgaagattat
    11761 ccaagaatct taaaagttag aagagttctt aaagataagg caaagtattt tgggccctat
    11821 accaatataa ctgctgtgaa tgataccttg gagcttataa gtagtacgta tccaataaga
    11881 agctgtaaaa tagatataga taaagcaata aagaataaga caagaccttg tttaaatcta
    11941 cacataaata aatgtttagg accttgtaca ggaaatgttt ctaaagaaga gtatggaaaa
    12001 atgatagaag agattataat gtgtttatct ggtaaagaag aaaaattgat ggaactttta
    12061 aaggaaaaaa tgaatgagag ttctatgaac tttagatttg aagaggctgc tgtatatagg
    12121 gataagataa agagccttga agagatgata cagaaacaaa aaatagatgc tactgtaagt
    12181 gacttaaacc aagatgtggt tgcaatggca agagctcata atgaagcttg tgtccaggta
    12241 ttttttataa gaaatggtaa gattgtaggt agggaacatt ttatattaga aggtgtaatg
    12301 gatagtccaa gagcttctat attaagttca tttgtaaaac aattttataa tgaacaagag
    12361 tatataccta aagaattaat tatagaagat gagatagaag atagttctat attagaagaa
    12421 tggctgtcat ctaaaaaggg gcaaaaagta acaataagag ttcctcaaaa gggagagaag
    12481 aaaagcttag ttgaaatggt taggaaaaat gctgtagaat atcttgaaaa attttctgat
    12541 atgaataaaa gaaaatatga aaaaagtatt ggagcattgg aagaattaaa acaaatatta
    12601 aatctagaaa agttgccaat aagaatagag gcttatgata tatcaaatat acaaggtgta
    12661 gattcgattg gttctatggt agtgtatacg aatgctaaaa aagataagaa ggaatatagg
    12721 agatataaaa taaagacagt tattggacct aatgattatg attctatggc tgaaattgta
    12781 gatagaagat taaaacatgg aaatttacct gacttgatat tgttggatgg tggaaaagga
    12841 caagttagtg cagtaaaaaa agtactagaa ctcaatgatg tagatatacc tctttgggga
    12901 atgtacaaag atgataagca tagaactaaa ggattgatat gcaaagaaaa agaaatagaa
    12961 ctagataaaa caactaattt atatagattt attgctagta tacaagaaga agttcataat
    13021 tatgcaataa catatcatag aagtctaaga aataaagctt tgacaaaatc tatcttagat
    13081 gatatacaag gaataggtga aaaaagaaag aaatcattat taaatcactt taaagatgta
    13141 gaggctataa aaaaagctac tatggaagaa attttagaag tagatggaat gaataaaagc
    13201 attgcagata atgtttataa tttttttaga aaggaagaaa attaatggaa actagcaata
    13261 aagtatcaat aagagagata ataaaagagt tgaagttaaa agtagtatac atgcctgatg
    13321 atgtagatta ttatgtctac tctcaagata taaatagacc aggattacag tttgcaggat
    13381 attttgatta ttttgcatat gaaagaatac aaatagttgg aaagacagaa tataattttt
    13441 ttggattaat ggatagtcat attcgagaag aagtattaga tagatttttc tcatatgaaa
    13501 taccagcgtt aataatttct agagacttgg aaatcaagcc agatgtaatt gaaaaggcta
    13561 aaaaatataa aagaatactt ttgagcacaa atagaaatac cactagactt ataaatagac
    13621 tgtcaaacta tttggataat aagttagcac cacacacaac aattcacggg gtgctagtag
    13681 atatttatgg tataggtgta ctgataaaag gtgaaagtag tataggaaag tcggaaacag
    13741 cattagaact gattcaaagg ggtaatagat tagttgcaga tgatgctgta gaaataagaa
    13801 aattagatga aagtatgctt gtgggtcagt cacctgaact aataagacat tttcttgaga
    13861 taagaggaat aggaataata gatgttagaa gtttatatgg agtaggggca atcaaaaatt
    13921 ctaaaatgat agatttagta gttcatttag aagcttggga tgaaactaag tattatgata
    13981 gactaggact ggataaagaa tatgaagaaa tacttggtgt taatgtagag aaattagttg
    14041 tacctgttaa acctggaaga aatactgcta tgatattaga agtagcagca atgaatttta
    14101 gacaaagagg aatgggatac gatgcagctc aagaatttac taaaaaatta tcaaaattaa
    14161 tcgatactaa gtagtactga ataatagtga actacacatc atttaattaa atattgatta
    14221 ggattatgtc ctacacctta taaattaaaa tcaagttgta tatatataat gtttattaat
    14281 aagatatatt atataaggat aatttaaagt acagtgttag attataataa tactagatta
    14341 attttatatt tgagtttcat tatataacaa gaaagttgga attttttatg ggaatagaat
    14401 attttagtaa acttttagaa agtagtactg aaaaagaatt gctcttaagt aaaaagtcaa
    14461 ataacataag tacagcaaga ttaatatctt ttttgatagt gatagcaggg cttgctattg
    14521 gattttacaa taaaaatata gtaggtattt ttgttggagt tttatcaata ataatattta
    14581 tagcactctt agttattcat agtaaagtaa aagaagaaga aacatatttt aaaagtaaga
    14641 gcgaagtatt aaataagtat attaagagat ttggagatgg ttggaaggaa tttaaaatag
    14701 atggtaaaga atacttaaaa gatgaaaatt cgcaagcaaa agatttagac ttatttggaa
    14761 gagcatcatt gtatcaatat atctgtgtag ctaatacatc ttatgggaaa aattttttag
    14821 ccaaatattt gtggaatgaa aatccagatg agaatgtaat cttagaaaga cagagggcta
    14881 taaaagaact tttatcaaaa gatgattttt ctattcatat tcaaatactc agtaatataa
    14941 ttggtaaaga gcaaaaaaat aattcagata gtagtataga atcgtttata gagtatggag
    15001 aaaataagaa tgtgtatata ccaaaatgga tgcatatttt tacttggggt ctaccaactg
    15061 caacaatctt atcttttata ttttgtatgt taggattttt acctgtttta cctgtttttt
    15121 tactttttat aatccagtta gggtttagtg gttttggata tccaagactt atgcaaactc
    15181 tttctccatt attttcattt agtagaagta tacaagtata tgaaaaaatg tttgaggttt
    15241 tagaaaaaga gacgtttgag agtgcatatt tgaaagaatt acaagataaa ctttctaagg
    15301 gaagtggagt ttcaagaggt gttaaacaat taaattcaat aggaaatgct gtaaacctaa
    15361 ggtataatca gatactatat ataattgcct gtggtgtttt gatgtggaac tatcattgtg
    15421 cagaagcttt ggagcgatgg aaaggtatat atggaaatca aattagagat tggtttgaat
    15481 ctattggaga atttgaagct ctaataagtt taacagttat ttctcatgta aaggaaaata
    15541 catgttttcc agtaataaaa tatgaagata ctccaagatt gaaagttgaa gaggtatacc
    15601 acccattaat agcagaaaaa agtgtcatag caaattcgat acaattaaat tctcagactt
    15661 gtattatcac aggttcaaat atgtctggaa agacaacatt tttaagaagt atcggtgtaa
    15721 acttagtgct ggcatatgca ggtgctccag tatgcgctaa gagttttgat gcgacctgta
    15781 tggctatatt tacttctatg agaatacaag atgatgtaag tcaaggaata tcaactttct
    15841 atgctgagat tcttagaata aaatcaatga ttcaatatag tttaaaagaa ctgccaatgt
    15901 tggttctagt agatgaaatt tttaagggaa ctaactctgc tgatagaatt attggagcaa
    15961 gtgaggcagt aaagaaatta tcaaaaccct gggttataag tatggtgaca acacatgact
    16021 ttgagctatg tgacctttca ggtagtggag atgttgaagt tgtaaactat catttctcag
    16081 agtactatgt agacgataaa attcattttg actataagat aaaagatgga agatgtaaaa
    16141 ctacaaatgc aaaacaactt atgagaatgg caggtattct ttaattaata gataggttaa
    16201 ttaaagaata agtctattta gaaatataat ttaatttgtg aaattaataa ggattgtctt
    16261 aaattacgta aaagtatttt aagacaatcc ttttttaaga ataaatttta tactttgtta
    16321 tgactactta gcttcttcac aagcacattc ttgtggacac tctccataga cacaactctt
    16381 atcaaagtaa tgagtatgaa ggtatttatg ggctacatca ctatttggtt ctccaaagaa
    16441 gtctttataa atagcttgta aatcaggatt ctcatgagat ttacgaatag ccttatttct
    16501 atctatttca tataacgcat ttgcacgtct atcaactatt tcagtattac catggtgata
    16561 aggttgacca gcacctccaa cacatccacc aggacatgcc ataacttcta tgatatggta
    16621 tttacattct ccacttctga ccttatccat aatctttcta gcatttttaa gtgtatttac
    16681 aatacacaca ttaactgtag ttccatcaac atctatactt gcttccctaa ttcctttaag
    16741 acctctaaca ttagtgaagt ttacattatc taaagtctta ttagttatct tctcatatga
    16801 agtacgtagg gcagcttcta aaactccacc acttgctcca aatatagatg cagcacctgt
    16861 agattttcct agaggattat caaaatcttg gtcttgaaga ttaggtaaat cgatagcagc
    16921 ttcttttatc attttagcta actctctagt agttatagaa aggtcaacat ctagtattcc
    16981 agattcactt aattcttctc ttgaagcttc atatttttta gccacacaag gcattacaga
    17041 tacaacataa agttcttcag gattgattcc taatatttta ggtgcatagt agtttttagc
    17101 tatagaacca aacatacctt gaggagactt acagctagat gctaagttta acttgtctgg
    17161 ataattgtgt tctaagaagt ttacccatgc aggacaacaa cttgttaata taggaagatt
    17221 ttcacctttt tggattcttt ctataaattc agtagcttct tccattatag taaaatctgc
    17281 accaaagttt gtatcaaata catgttcaaa tccaagtgct tttaaagcag ctaccatttt
    17341 tcctgtagag attgaccctg gttctaatcc aaactcttca ccaatagcaa ctcttacagc
    17401 aggagcaact tgcactacta tagtcttttc ttttttattt aaaacatccc aaagtttagg
    17461 tacattatct acttctgtta atgctccagt tggacagaca gatatacatt gaccacagaa
    17521 tgtacactct gtttcaacca tatcagagtt aaagaatgta ctaactaaag tattaaatcc
    17581 acgattaact ccagataatg ctcctactgt ttgtatgtca ttacatacag tctcacatct
    17641 tctacataat atacacttag aatggtcttt aactaaagat ttagtagaag tatctttacc
    17701 tgcaaaagat ttggaacctt gatatcttat ttttcttact cctaaatcag cagctatagt
    17761 ctgtaattca caatctccat ttttttcaca gacaaaacaa tcttgtggat ggtctgataa
    17821 caataattca acaatagttc tacgagcatt taatgcttta gcactattag tctgaacttt
    17881 cataccttcc tttataactg ttccacaagc tggaactaat cctctctctg tctcaaccat
    17941 acaaacacga caagaagcac aagtgtcaag cttatctatt tcattcatat gtaagtgaca
    18001 aaggttgtgt atttttatat ttattaattt cgcagcatct aagatagaag ttccactagg
    18061 tgctgaaacg tgtttgccat taatagttaa attaactaaa ctcattgtta ttcctcctcc
    18121 aaataagtta tttcttgatt atagcgttaa atgtacaatt atctatacaa gcaccacatt
    18181 ttagacactt agaagtatct attgtatgtt gttccttaac agaacctgtt atacaaccag
    18241 caggacacac tctagaacat tttgtacaac ccttacagtc atctgttata aagtaagaaa
    18301 gtaagttctg acatttacca gcaggacatt tcttatctac aacatgagct atatactcat
    18361 ctttgaaata ttgaagagta cttaaaacag ggtttggagc agctttacca agaccacata
    18421 atgaagcagt ttgtatagtt tcagcaaggt tttctaggtc atctaaatct tgtagagtac
    18481 cattaccttc tgtaatttta gttaatattt ctaataatct tgtagtacct atacgacaag
    18541 gtgtacattt accacaagat tcttcaacag taaactcaag gaagaacttg gctatatcta
    18601 ccatacagtc agattcatca agaacaagca taccaccaga gcccatcatt gaaccgatag
    18661 aacttaatga accaaagtct ataggagtgt ctaaatgttc agttggtata catccaccag
    18721 atggtccacc tgtttgaaca gccttaaatt tcttaccttc agggattccc ccaccaattt
    18781 caaatacaat atctcttaaa gtagtaccca ttggaacttc aacaagtcct acattttcta
    18841 cttttccacc aagagcaaag actttagtac cactagaatc ttcagtacct aagttggcaa
    18901 accaatctcc acccttaagt ataattgcag gtatgttagc aaaagtctca acgttattta
    18961 agcaagtagg agatttccat agaccactct tagaagaact ataagttttc attctaggtt
    19021 caccacgtct accttcaatt gaatgcatta gcgctgtacc ttcaccacaa acgaaagcac
    19081 ctgcaccata ttttaattct aatttaaagt taaatccagt gcctaaaata ttttcgccaa
    19141 gtaaaccgta tttttcagct tgagctatgg ctacttttaa tctttctata gattttggat
    19201 attctgctct tatgtatatg tatcctgtat cagaacctat agcgtatcca catattgcca
    19261 tagcttctag tacactatga gggtcacctt caagtacaga tcgatccata aatgcacctg
    19321 ggtcaccttc atcagcatta catacaacaa actttttatc tgttggacca gctggatttt
    19381 ttgaagcagc ttcccattta gagccagtag ggaaacctgc accacctcta ccacgaaggc
    19441 cagaagtttt tacctctgca ataacttctt gaggagtaag agaagttaaa catttgccta
    19501 gagctaaata accatcattg gcaatatatt cttctatact atctgggtct ataagaccac
    19561 aattttttaa agctatacgt aactgttttt tgtagaaaga catttcttct tgttcttcaa
    19621 cttttttact taaagattct tcctcatata ataattcctc gacaactgta tttctaatta
    19681 agtggctttg aactatcttt tcagcatcag atggctcaac ttttacgtag aaaacgttat
    19741 caggataaac ttttacaata ggaccttgag cacagaaacc aaaacaacct gtcaaacgaa
    19801 cactaacttt atcttggatt cctgatttct ttatttcatt ttctaattca ctaactattt
    19861 ctagactgtt tgaagaggta catccagtat cacaacaaac aagtaattct cttcttaata
    19921 cattttcctt agaataattt tttcttaagc taagattagg tttcagctca tcagctaaaa
    19981 cttttaattc atcaaatgaa tttactttac gcattattta ttcacccctc ttaacaattc
    20041 aattctaatt ctctataagt atctaatatt tcgcttactt ggtcaggttt cactttacca
    20101 taaactttac catttacagt aacaactgga gctaaaccac atgcccccaa acatcttaaa
    20161 ccttctaaag aaaatttaaa atcactagta gtttctccaa cttttatgcc aagctgtttt
    20221 tcaaaagcac ttaagatttt gtcagcacct tttacaaaac atacagttcc tagacagaca
    20281 ctgattttat acttacctac aggttctgta gtaaaataag aatagaatgt aacaacccca
    20341 tatacctttg caggagctac tccaagtttt ctagcaacat gaagttgaac ttcttttgga
    20401 agatatccaa atataccttg ggcttcatgt agaacttgta ttaacgcacc ttcctttgtt
    20461 gcaagagagt caataaatat atctagttcg tcaaataatt gcttgttgtg tgaaataaaa
    20521 tcgcacataa caaatccccc ttttcttttt aaagttatta tttttcataa aataattaac
    20581 catgagttga ccccaacatt atgtgggtga acaaaaccaa aacaataaag aaagaataat
    20641 atacaacaat ttctttattt ataaaaacaa tgcaaaaaag ttacctatta aaaataaaaa
    20701 ctatactagt ctattataat ataaaataat tcagaatagt taaaaaaaat aaaaaaaatg
    20761 agctaaattc aataaaaaaa aaataataca tataaaaaac tttaaaaaat aaaccaaaat
    20821 gtaaaatttt tataaaataa aagatttata aaactgctga taatagtctt gaaattgatt
    20881 ccttgatttt tatataagta gacctagaat tatatatatc taatgttatt tccttagaat
    20941 ttaaaatatc attttcaaat ataattcttt gttccaatgc tttttttgaa gagtacataa
    21001 atgcattaac ttcgaaatta agctcaaaac ttctgatatc catattagct gttcctatag
    21061 agcatataga gtcatctata actattgtct tagcatgtaa aaatgcattt tgaccataag
    21121 tgtagatttt agctccaaac tttaaaagtt ctccagcata tgaatatgat gcccagtata
    21181 caaagggatg gtcaggttta gaaggaatca taactctcac atcaacacca gataaacaag
    21241 ctatttttaa agtatctata aaagttgagt caagtattaa ataaggactc tgtatgtata
    21301 tatactttct agctttctga atcattttaa gataaccata tttaatctca tcaagttctg
    21361 atatatctgg accacttgat actatctgaa tcccaatatt ttcagaagga tgattagaat
    21421 ttgtatcttc ttctataaag tacttttcta aatctaaatc ttctttagtt gtatatctcc
    21481 aatcaaggat gaatctcata tttaggtcaa ttacgcaatc accagtaagc ttagtatgtg
    21541 tatctctcca tagaccaaat tttggatttc tacctaaata ttcatcacca acattatatc
    21601 cacctacaaa tcctacctta ccatcaatga caacaatttt tcggtgattt ctatagttta
    21661 agttaaagtt tacaattttc aagaatgatg ggaagaagct tccaacttta acaccacttt
    21721 ctttaagtct ggaaagtgta ctatttttta gtgttctacc accaactgca tcaaataaaa
    21781 gtcttacttc aacaccttct ttagctttgt ctataagaat gtctattatt tcagttccga
    21841 ttttgtcatc tttgaaaatg taaaattgta tgtttatata ttttttagct tttttaagtt
    21901 cttcaagaag actgttaaaa aattgactag attcagcata aatccacaca tcgttattat
    21961 tggtataatg agcattattt gaattagcca atgcataaat catatcctta tgttgatgta
    22021 tatctgaatc aatttcagat gtagattgga gtttaacctg agtatctagt atattacttt
    22081 tgattatctt atcatccttt tctttcaatc taaacatatt gttttttgaa atatttctgc
    22141 caaaagctat ataaagtatg aatccaagag caggaatcaa tactaatata agaagccatg
    22201 ttaaagttgt atttatgttt cttttttctc taaagataag gtttagtata accatgaaat
    22261 taattatata tattgtagta actgctattt catatattga catttcgaaa aatgatatat
    22321 caaacataaa attccctcct tcaaatattt attaaaataa gtaattatat ataataacac
    22381 aaacatatat ctattatata taatacctca ataattaaaa agtaaaataa ataatcaaaa
    22441 ggtaaatttt tcaaattcaa tataaattat ttcgaaatta acaaagttgt tatataataa
    22501 atagtataat
//
LOCUS       DACTZW010000070        22498 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.070, whole genome shotgun sequence.
ACCESSION   DACTZW010000070 DACTZW010000000
VERSION     DACTZW010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22498
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.070"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     regulatory      60..145
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            269..6232
                     /locus_tag="JAM15_13735"
     CDS             269..6232
                     /locus_tag="JAM15_13735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-binding adhesion protein"
                     /protein_id="HAT6799316.1"
                     /translation="MKKAISCVLAVSMCSAPLNVFAEPILEGKLRAVEKSVTEKLRGS
                     LEVDLNFSLPIKNSESESMTNMQLRLKDDSNNSGIIKLGEKDSGTVNVGTDNIEYTIK
                     KLSASRSEIKNKDENVSYYNIVFNNLPVGKYNVEVSGAGFKNKEIKDIDISSYSQRVL
                     LSNRASVDNKNKPLNYELFLMGDVNGDGKVDKSDYNKVLENIDSNKREFDLNRDGKVD
                     IVDLDYVQKNLGQSEDAKSLESIVSTNPIVDTSKVELKGNSDVDINGNVENLFSGENN
                     GVTISSKNDEISEEKPAVMDIALSEALNMEVINIKAPEGTAPAKGIVEVTDEDGNVQQ
                     IPYENKEYMKNLKDKEQQEEVNNEQEEVNQEEVNNKDENKNQTDNNSNNKDENNDKQQ
                     ENSDKQEVNSNTNQDKNNDKENSSMDKPNSDEDTPKEGDNISKDDNSTTSTYSRAALE
                     TYADVQNSDIVINLGKQVAVKKITIKITATTANDRNLAEISKVEFLNNVYKEIPKPEM
                     NIPKINKISTSTAVGNEKVSFYWNNEVNVSAYELILDKIDSKGKVLSTKKLQTSKNTI
                     EVRDIEAYGLYRVSIQSLNGDWSSGYKDATPENLDGVPENVDLNYKPIQFSPDSILEF
                     QVVPDTKPEPPEGINVKGKFKSLDVSWKNHKQAKDFDLYYKEKGSNGSWIKYNDKLIR
                     GTSSKIEGLKDNTTYEVRMTATNHLGTSGMSKTYIGTTESIDAPTTPNYRLINTPKEN
                     GGFGIPTNHIVDVVYPAGYDKSEYSDKNPFDKFNVVDGDFTTHWTFPTYNAAEGTNRG
                     PIITFDKSYTMDTFMATPRFDVSDKTINDFEVRYWDENGQLHNLGDVPFETKTDPVNN
                     NKYVMVRLKEPITATKIQVSVCSSYSYKSNISELKFYEYDSIEDDVRNLFMDDLQVEL
                     KEDVTQEKITELKDRLNTPDKASGEYHPYKTVIDRELKLAQDLYNDRATLTDVTTVNQ
                     EINKSGKYKDKNGQYTVNSNNLGMQNDWQALGVAARAGDEITVYVGSKSGKTPKLIYT
                     QYYGESGAYKSGEINLKTGKNVIQLSKLHSLDIECGGSLYIRYPEDAPSGGDIKVRVA
                     GATKIPHLNLNGTINDKSPAGVSESKKKIKAYIEELAKYKDAVKGEPYYPGTNIGNSY
                     EYSEKTGVLNTTDIESDKVTLNVPATAVYQGISEGNADLNTQVDRLYNSMLAWEQIMD
                     LVYSERGVFKTQDLDGNGTVDDNEFNLTKNDMAPKSRMNIKYQRMFIGAFMYASGLHV
                     GVEYGSVPGLMNGVPFQIDDSGKATGGNLFGWGIGHEIGHVTDIGKMTYSETSNNVLA
                     LLAQTFDDKTHSRLEGSTMDKIYEHVTSNSLGIPSNVFERLGMLWQLHLAYDDDFTGS
                     MLKNNSDADLSNDTFYAKISRKYRVLSSSDPINSLPKDQMLVAMASSVVEKDLRDYFK
                     AWGVEITPELNSIMDSKNYEKESRKIQYVNDEARRKILNENIASMAKDTKVSASFSDG
                     IQSGSLVKSNKISIDLDVDKDKDKILGYEIIRSDGNYLDGENGTQVKYRTVGFVDAKG
                     NSKAKFTDNISPLNNRAFTYKVVAYDYHLNPTEEFEVGTVKLSDEGKINKSAWSFITN
                     TVSDGDVRTENDSHGPLQNPEIDNIKDNDASTTYKGKIISKAEWNKDPQKDPDINVEE
                     NPYIIVDMKETLPIVGLKYTKPETEARKFSLKGLFNFRKNTSTTYNPLTNYKIQVSND
                     KKNWEDVSQGTFEYGQDLVGGGKDQDNEARVTFNKDGKLWTYQARYVKLISNNKSNIE
                     VAELDIIGPPGDNIEIGTMNNVDQTRTNGIGKLAEDYVYQSDDPSTSEDETGKIPAGS
                     IIITGEYSGNPAFNLPLLIDKNNKTISGEALLFAEVPEKGELGEISKGTWVYYMPKEN
                     FDSLSDKVKAELYRYNDLQGDTPVGQRFVSDTMYVPVGAKNYDELKTISLTDSNSKAR
                     KATRNAIDVSNKKVITVSNKVKGNIVRDK"
     gene            6442..8322
                     /locus_tag="JAM15_13740"
     CDS             6442..8322
                     /locus_tag="JAM15_13740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp10"
                     /protein_id="HAT6799317.1"
                     /translation="MSKRKSFIRTIAVSTMAVAVTGSATCAYAAPVLQGRKTYEKVNT
                     IDISVDSVENIVYSFQASIKVQGEVEVVDNEQKEKITWSDNIKSQIKSGNANATCRAE
                     YNKSSNTTTLDIYVTSNEDLLDGNRLNIGRISVKKSGSNSNADYKVLGKGTSDKPALK
                     IVTYNNKTVDYENINSDEGLIFTLINESEVKPIGGTGSSKNDPEKYKVEKSEALEYLL
                     NNIRINYSIVSKETQESGSNVILKLGLAQKTTKGRKTTINKYVEVTLPKSLEYIVENE
                     LSKPDELPPDNGNGGNNGAGSNSGGSSSGGSSGGGSSSNSTSNVTVKKLKGADRFETA
                     TKISQSGWTKSDTVVIVNGEDKSMVDGLTATPLASVKNSPILLSSNEKLPQKTVEELK
                     RLNPSKVIVIGGNNSMPNSVVEAIKAVNSKISVQRIGGDTRYQTSINIAKEIDKTNNV
                     SKLYIGAGNGEADSLSIASLAGKEKTPIVLTQKDGVDNEAVQFIKSNKVSNIYFIGGI
                     EKISNKAIEQVGKIVNKDISNNRVAGQTRQETNAKVIDKFYSQSKLDGVVVANQDKLI
                     DALAVGPLAAKNNSPVILATNMLDKSQESSLKGKNSSKLFEVGGGIASSVIDKIKSLI
                     EK"
     gene            8689..10290
                     /locus_tag="JAM15_13745"
     CDS             8689..10290
                     /locus_tag="JAM15_13745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp11"
                     /protein_id="HAT6799318.1"
                     /translation="MKMNKKILSLGLAVSLILVNFKSVNASSVVEKIYGKDRYETAAK
                     IADKQTYETVILVNTEKSLADGLSASGLSGATKAPILFTQKNKIPADTNRCLKNIKKA
                     YIIGTEDTISKSVEKELDSKNIEVKRIGGEDRLKTSYLIAKEIATIKKVDKVLLTNAY
                     SGEADAMSVSSVATRDGAPIILTDGKSVPFDVKNIQSYCIGSEEIMSNPLVKNTNSVR
                     IEGTDRFETNKNVIDYFFNSADGFYVSDGYQLVDAIAAAPLTKNSPMVLVNDGSDKTV
                     LEGAKNITSVGEINEKVIQQCINASKSNGQPPTITVGSTEIYKGEKFDTGKLNIVAKD
                     NTGKVLPIEVDGFIDTNRVGTYILTLKATDEWGKSTGKRIEIKVLDDKSYDYNSPEFK
                     KMVSTEMYNLINSYRKEKGKEPLVVSSRLEGMANAWSKYMMDKKVFAHYIDGKNAPQV
                     FSEFGMRSEENIAYIYIDSKNVQTTQDAKDLAKAIFEVWKKSPEYNANMLSNEFYSTG
                     FGLYILSDGQVHATQEFLNGNEGSL"
     gene            10509..12107
                     /locus_tag="JAM15_13750"
     CDS             10509..12107
                     /locus_tag="JAM15_13750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HAT6799319.1"
                     /translation="MKVNKRVLSIGLAISLIMAGAPNINALSSIEKIQGKDRYETSAL
                     IADKQIYDTVILVNTDNSIVDGLSASGLSGVVKAPIMLVQRDKIPTDVEKRLKDVKNA
                     YVIGTEDTIGKSVENQLKNKGIEVKRIGGEDRIKTSYLIAKEISAIKPVNDGDKVFLV
                     NGYTGEADAMSVSSVAARDGVPVILTDGKSIPFKADGVQCYSLGSEEIMSNELVSKTN
                     SVRIAGKDRFETNKKVIQRFYKGTNKFYVSQGYKLVDAVAGSPLAKNRPIVLVDDRSD
                     KSILKGAVEVTSLGGMDKKVIEQCIDYASDKNTLPTITANNIEIFVGDSFNNSMLNIV
                     ATDYHGNELIPNIQGKVDTKKAGAYILNIYAIDSLGQKCEVSVNVKVIVNTSTKDPNS
                     YEFKAMVTNEIYNLVNSYRTEKGKKVLKESKSLSGMANAWSKYMDEKKVFAHEIDGKN
                     AAEVFFGFGARSDENIAYLPMNVKSVYTSKDAKEIAKSIFDLWKKSSKYNESMLKDEF
                     YSFGFGMHVSSQGEVNATMEFLNS"
     gene            12395..14593
                     /gene="slpA"
                     /locus_tag="JAM15_13755"
     CDS             12395..14593
                     /gene="slpA"
                     /locus_tag="JAM15_13755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein SlpA"
                     /protein_id="HAT6799320.1"
                     /translation="MNKKNLAMAMAAVTVIGSAAPIFADGTAVKEEGYTVVQDKYEKL
                     LKELKAKINDGTITSVGVEFDGSSIGTVAPTSDSTADKKTAADKLETLTKNQLKGLGD
                     GKYVDFKITYGAKAEVPAATLSAEDIQKYADQINASTTKLVDVAGSEAGIATFDSANS
                     KIVPGAAPLTIKDAVKATVSESGGKKLLTITAADTLVNFKYGELKGSGANGSEIEAIT
                     LGTSDLTVTEGDNKKIDVDKSFAFDKSTKKLAGLSLTTTEKTPADPGSTITVRVIKAV
                     EKTIDVSSSSTTKAKDLAKQYVFTDVSDTDPESLSYMLKNINDGKVAVKNSDGDWEVT
                     IFPEGKRLNTLSASSTKTILGDKDTPAKIVLKASTTKKIADYIDDLITYNNSYSNVQT
                     VAGSDRIETAIELSRKYYNSTDKNALYENPVDNVVLVGSQAIVDGLVASPLAAEKGAP
                     LLLSSKDKLDSATRAEIKRVMDLNSSTGIKNNKEVYLAGGVNSISKEVENELKDMGLK
                     VTRLSGDDRYETSLAIADEIDINDKAYVVGGTGLADAMSIAPVASQIKDGEATPIVVV
                     DGKADKLSKEAEDFLDDAQVDIIGGENSVSAKMEDYIDDATGKSPERISGADRQATNA
                     EVIKEYFDKDKVSNYFLAKDGSTKEDQLVDALAAAAVAGNYGSKHNADGAITTEASPA
                     PIILATDNLSAEQHVAVSKTATTSGAKNLVQVGQGIADSVVSKLKDLLDM"
     gene            14839..17181
                     /gene="secA"
                     /locus_tag="JAM15_13760"
     CDS             14839..17181
                     /gene="secA"
                     /locus_tag="JAM15_13760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002842775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HAT6799321.1"
                     /translation="MSVLDVILDKKDELEIKKLNNIVDKIDELENEIQVLDDEALKNM
                     TNVFKDRLNKGETLDDILPEAFAVVREVSRRILGMRQYRVQLIGGIVLHQGKIAEMRT
                     GEGKTLVGVAPVYLNALTGKGVHVITVNDYLAQRDKELMQPVYEFLGLTVGVIINGQE
                     PVERKLQYQCDITYGTNNEYGFDYLRDNMVTREIDKVQRELNFAIVDEVDSILIDEAR
                     TPLIIAGEGDEGTKLYELANAFIKTIKDEDFEMDRKDKTIALTASGLSKAEKFFGIEN
                     ITHIDNIEIFHHVNQSLRAHKLMDIDVEYVVRDNEILIVDEFTGRIMDGRRFTDGLHQ
                     AIEAKEGVKINDESKTMATVTFQNFFRLYSKLSGMTGTAKTEESEFEDTYKINVVQIP
                     TNKPVIRADLHDKVFKTERAKYNAVVEEIIRINATKQPVLVGTVSIEKSEKLSKLLKK
                     KGVKHEVLNAKQHDKEAEIISKAGKLGSVTIATNMAGRGTDISLGAGDKIEEEKVKEL
                     GGLYVIGTERHETRRIDNQLRGRSGRQGDPGTSRFFVSLEDEVIKLYGGKSIEKILKR
                     MNANEDEALESKSLNRAIERAQKGIEGKNFEQRKNVLKYDDTINEQRKVIYNERNKVL
                     SGSDIEDEIQKMVMDIISDAAEKYLKKNRDYHGYFKYLYNTFMPADTLLIPNLDEKSV
                     EEIISQTYQISKRVYDLKKMMVGIEELAQLEKRVLLQVVDTYWVDHIDAMDQLRQYIG
                     LKSYAQKDPFKEYAIEGYDMFEALNKNIRVTTVQYLYKFN"
     gene            17599..19470
                     /locus_tag="JAM15_13765"
     CDS             17599..19470
                     /locus_tag="JAM15_13765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HAT6799322.1"
                     /translation="MNRKGLSVIIAAAMVSTSVAPIFAAETTQVKKQTITKKEATELV
                     SKVRELMAQRYTGGSQVGQPIYEIKVGENSSKLKVITNIDELEKLVNALGENKELIVT
                     ISDKGHVTNSANEVVAEAIEKYENSADLSAEANSITEKAKAEANGIYGVATVEASYDS
                     TRDKLVITLKDKTDVITSKTLEIGIGDEKVDLTVNPVDIAGTNLDTSAEGFRVNKINK
                     LGVAGAKNIDDIQLAEITIKNSDLNTVSPQDLYDGYRLTVQGNTIANIAGKLISDISA
                     KDSETGKYKFTVKYTDTSGKAIELTVESTNEKELKDVKAALDGNTKVNLIAGEDRYST
                     AVAIAKQTKYTDNVVIVNSNKLVDGLAATPLAQSKKAPILLASDNEIPKVTLDYIKEI
                     IKKSPSAKIYIVGGESAVSNTAKKQLESVTKNVERLAGDDRHTTSVAVAKAMGSFKDA
                     FVVGAKGEADAMSIAAKAAELKAPIIVNGWNDLSAEAIQLMDGKEIGIVGGSNNVSSQ
                     IENQLIDIDKDRKVQRVEGETRHDTNAKVIETYYDKLDKLYIAKDGYGNNGMLVDALA
                     AGPLAAGKGPILLAKTDITDSQKNALDKKLNLGAEVTQIGNGVELTVVQKIGKILGW"
     gene            19580..20287
                     /locus_tag="JAM15_13770"
     CDS             19580..20287
                     /locus_tag="JAM15_13770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HAT6799323.1"
                     /translation="MIEATLFFSPHQDDETLSMGSAIIEHVEKSDTHVILCTDGSKSI
                     IRKVLDDGGTCSYHIKDVHKYSLSESDFSKNRDEEFKDSCKAMGVKENNIHIENNRAH
                     DGELSKEKARDIILKYLEKYPDAKVKTVTPYKALGIHEDHRALGEAALELYKEGKIKD
                     LRFYVEPYDYNDFKKVNPNVRVWKVLSSQEEKLLNAMDAYKKWNPENGNYAIGYHSVK
                     SHFDELKSNKIQYVHAP"
     gene            20320..22452
                     /locus_tag="JAM15_13775"
     CDS             20320..22452
                     /locus_tag="JAM15_13775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HAT6799324.1"
                     /translation="MKISKRIMSLLTATFFIFALSINIADASSKESLVGSGRWETAIK
                     ISQNGWKEATNAILVNDNSIADALSATPFAKLKDAPILLTQSDKLDSRTKAELKRLGV
                     KNVYLIGGMNTLSTNIEKQLKSENMTFERISGNSRYETSLKLAERLDKEKSVSNIVVV
                     NGEKGLADAVSVGSIAAQENMPIILSDPNNGIKVANNFISSKNIKKSYIIGGTYSVSS
                     SIEQSLPNAKRLSGNNRNETNAKVVEEFYKDTDLKNAYITKDGMKKQSDLIDSLAVGV
                     LAAKNSSPVVLVGNALDSSQYDVLNTKSFDNIVQVGGNGNEDAVKDILDLQEETIYRV
                     KTADELAVALRKADANDIITFKPDDNKKITSSFSIETKKAITVELEGLYTQTITVNMP
                     NGELTNKGTLDGTVKIMDIKNGTFINEGEINDIDLYDSNGSKIENKSGGDIWVLTISS
                     SAKDVNIENKGDISKITNNSTSVIIKNSGNIDTLGGISTPSISGNKPRVDDTDKDEKR
                     ASGIYPTSEPLSSPKPGYINVKIFTKPEDTNYKIYYRVVSSRPSALYIGDRIDTSDWT
                     AVPSSVLPFTIKAENGYYIEAVEINSDTKKVSRWGKSDYIDDGFYLKSETAKGLSADI
                     DFDGDYVKLTATGADSGCTVYYRIVSKKPASMNVGDKITISNWDEITTNRVKIEAKDV
                     KEKYIELVELDDSTNKVTRWGVSDKVVE"
BASE COUNT         9365 a         2494 c         4226 g         6413 t
ORIGIN      
        1 atgtaaaaaa attgtattaa aaagtttaaa tatagtataa aatgggtaag aaagtagtga
       61 aaattaaatg gcaaaattag ggaaatctaa tgacgcaaaa ctatagggat taaagctttt
      121 aaagccatat cagccagttg ctaaaaagag taaagtcttt ttattttata attaagattc
      181 tctttgagtg tcttttttta ttgtctgaaa cttatagtat ttaaattcat gaaaaattag
      241 atatttatta agggaggatt gttatttcat gaaaaaggca atatcttgtg tactagcagt
      301 atctatgtgt agtgcaccac taaacgtttt tgcagaacct atattagagg ggaagctaag
      361 ggcagttgaa aaatcagtta cagaaaagtt aagggggagt cttgaagtag atttaaattt
      421 ctcactgcca ataaaaaata gcgagtcaga aagtatgact aatatgcagt tacgattaaa
      481 agatgatagt aacaatagtg gaataataaa gcttggagaa aaagattcag gaacagtaaa
      541 tgttgggaca gataatatag aatatactat aaaaaaatta tctgcaagta gaagtgaaat
      601 aaaaaataaa gatgagaatg tatcatatta taatattgta tttaataatt tacctgttgg
      661 aaaatacaat gtagaagtct ctggagctgg atttaagaac aaagaaatta aagacattga
      721 tatatcaagt tattcacaaa gagtcttatt aagcaataga gcaagtgtag ataataaaaa
      781 taaaccttta aattatgaat tattcttaat gggtgatgta aatggagacg gtaaagtaga
      841 taagagtgat tataataagg ttttagagaa tatagattca aataaaagag aatttgattt
      901 aaatagagat ggaaaggtag atattgttga cttagattat gtacagaaaa atttaggaca
      961 aagtgaagat gcaaaaagcc tagaaagtat agtatctacc aatcctatag tagatacaag
     1021 taaggttgaa ttaaaaggaa atagtgatgt agatattaat ggtaatgtag aaaatttatt
     1081 tagtggagaa aataatggag ttacaatatc ttcaaaaaat gatgaaatat ctgaggaaaa
     1141 accagcagta atggatatag ctttatcaga agcacttaat atggaagtca tcaatataaa
     1201 agccccagaa ggtactgctc cagcaaaagg aatagttgag gttactgacg aagatggtaa
     1261 tgttcaacag attccttatg aaaataaaga atatatgaaa aacttaaaag ataaggagca
     1321 acaagaggaa gtaaataacg aacaagaaga agtaaatcaa gaagaagtaa ataataaaga
     1381 tgaaaataaa aatcagactg ataataattc aaataataaa gatgaaaata atgataaaca
     1441 acaggaaaat agcgataaac aagaagtaaa ctctaatacc aatcaagata aaaataatga
     1501 taaagaaaat tcatcaatgg ataaacctaa ttcagatgaa gatactccaa aagaagggga
     1561 taatatcagt aaagatgata actctacaac atctacatat agtagggcag cattagaaac
     1621 atatgcagat gttcaaaata gcgatatagt aataaatctt ggtaaacaag tagcagtaaa
     1681 aaagataact ataaaaataa cagctacaac agcaaacgat agaaatcttg cagaaatatc
     1741 aaaagttgaa tttttaaaca atgtatataa agaaatacca aagccagaga tgaacatacc
     1801 taaaataaat aaaatatcga ctagcactgc tgttggaaat gaaaaagtat ctttttattg
     1861 gaataatgaa gtaaatgtat cagcatacga acttatacta gacaaaattg atagtaaggg
     1921 aaaagtatta tctactaaaa aattacaaac tagtaaaaat acaatagaag ttagagatat
     1981 agaagcatat ggactatata gagttagcat acagtcttta aatggagatt ggtctagtgg
     2041 ttataaagat gcaacgccag aaaacttaga tggagtacca gaaaatgtag atttaaacta
     2101 taaacctata caatttagcc cagatagtat attagaattt caagttgttc cagacacaaa
     2161 accagaacca ccagaaggta taaatgttaa aggtaaattt aaatctcttg atgtaagctg
     2221 gaaaaatcat aaacaagcta aagactttga cttgtactat aaagaaaaag gttctaatgg
     2281 gtcttggata aaatacaatg ataagcttat tcgtgggaca agttcaaaga tagaaggtct
     2341 taaggataat acaacatatg aagttagaat gacagctact aaccacttgg gaactagtgg
     2401 aatgtctaaa acatatatag gtacaactga aagcatagat gcaccaacaa cacctaacta
     2461 tagattaatt aatactccta aggagaatgg tggatttgga ataccaacaa atcacattgt
     2521 agatgttgtt tatccagcag gatatgacaa aagtgaatat agtgataaaa atccatttga
     2581 taaattcaat gtagtagatg gggacttcac aacacattgg acattcccaa catataatgc
     2641 agctgaggga acgaatagag ggccaataat aacttttgat aaatcttata ctatggatac
     2701 ttttatggct acacctcgtt ttgatgtttc tgataagaca ataaatgact ttgaggtacg
     2761 atattgggat gaaaatggtc aattacacaa tctgggggat gttccttttg aaacaaagac
     2821 agaccctgta aataataata agtatgtaat ggttagatta aaagaaccaa taactgctac
     2881 taagatacaa gtaagtgttt gttcatctta ttcatataag tctaatatat cagaacttaa
     2941 gttttatgag tatgacagta tagaagatga tgtaagaaat ctatttatgg atgacctaca
     3001 agttgaatta aaagaagatg taactcaaga aaaaataact gaattaaaag atagattaaa
     3061 tactccagat aaagctagtg gagaatatca tccatataag acagttattg atagagaatt
     3121 aaaattagct caagacttat ataatgatag agccacactt actgatgtaa ctactgtaaa
     3181 tcaagaaata aataaatcag gaaaatataa agataaaaac ggacagtata ctgtaaattc
     3241 caataattta ggcatgcaaa atgactggca ggcattagga gtagctgcta gagcaggaga
     3301 tgaaataaca gtatatgttg gaagtaaaag tggaaaaact cctaagttga tatatacaca
     3361 gtactatgga gaatctggtg catataagag tggagaaata aatcttaaaa ctggaaaaaa
     3421 tgtaattcaa ttaagcaaac ttcatagtct agatatagaa tgtggaggaa gtttatacat
     3481 aagataccct gaagatgctc caagtggagg agatataaaa gtacgtgtag caggagctac
     3541 taagatacca catcttaatc taaatggaac aataaatgat aagagtcctg cgggagtttc
     3601 tgaatctaag aaaaagataa aagcatatat agaagaatta gctaaatata aagatgctgt
     3661 aaaaggagaa ccatattatc caggaacaaa tattggtaat tcatatgaat attcagaaaa
     3721 aactggtgtg ttaaacacta cagatattga aagtgataaa gtaacattaa atgttcctgc
     3781 aacagctgta tatcaaggaa tatcagaagg aaatgctgat ttaaatacac aagtagatag
     3841 attatataat agtatgcttg catgggaaca aataatggat ttagtttact cagaaagagg
     3901 agtatttaaa acacaagatt tagatggtaa tggaactgta gatgataatg aatttaattt
     3961 aactaaaaat gatatggctc caaaatctcg tatgaacata aaataccaaa gaatgtttat
     4021 tggagcattt atgtatgctt ctggattaca tgtaggagta gaatacggtt cagttccagg
     4081 gcttatgaat ggagtacctt tccaaataga tgatagtgga aaagctacag gaggaaactt
     4141 atttggatgg ggaataggtc atgagatagg acatgttaca gatatcggaa agatgacata
     4201 tagcgaaact agtaacaatg tacttgcttt acttgctcag acctttgatg ataagacaca
     4261 ttcaagactt gaaggttcaa caatggataa gatatatgag catgtaactt caaatagctt
     4321 aggtatacca agcaatgtat ttgaaaggct tggaatgtta tggcaattac atctagctta
     4381 tgatgatgat tttacgggtt caatgttaaa gaataactca gatgctgatt taagtaatga
     4441 cacattctat gcaaagattt caagaaaata cagagtactt tcaagtagtg acccaattaa
     4501 tagtttacca aaagaccaaa tgctagtagc aatggcatca agtgttgttg aaaaagattt
     4561 aagagattac tttaaggcat ggggagtaga aattacacca gaattaaaca gtataatgga
     4621 tagtaagaac tatgaaaaag aatcaagaaa gatacaatat gtaaatgacg aagctagaag
     4681 aaagatttta aatgaaaata tagctagtat ggcaaaagat actaaagtaa gtgctagttt
     4741 ttctgatgga atacaaagtg gttctctagt taaatctaat aaaatatcta tagacctaga
     4801 tgtagataag gataaagata agatactagg atacgaaata ataagaagtg atggaaatta
     4861 tttagatggt gaaaatggaa cacaggtaaa atacagaaca gttggatttg tggatgcaaa
     4921 aggaaatagt aaagctaaat ttactgataa tatatctcct cttaataata gagcatttac
     4981 atataaggta gttgcatatg attatcacct aaatccaaca gaagaatttg aagttggtac
     5041 tgtaaaatta tcagatgaag ggaaaataaa taaatcagca tggtcattca taacaaatac
     5101 tgtttctgac ggtgatgtta gaactgaaaa tgactcacat ggaccattac aaaatcctga
     5161 aattgataat ataaaagata atgatgcaag tactacatat aaaggaaaaa taataagtaa
     5221 agcagagtgg aacaaagacc ctcaaaaaga ccctgatata aatgtagaag aaaatccata
     5281 tataatagta gacatgaaag aaacattacc tatagtagga ctaaaatata caaaaccaga
     5341 gacagaagct agaaagttct cattaaaagg attatttaac tttagaaaga atactagcac
     5401 aacatacaat cctttaacta attacaagat acaagtaagt aatgataaaa agaactggga
     5461 agatgtaagt caaggaactt ttgaatatgg acaagattta gttggtggag gaaaagacca
     5521 agataatgaa gctagagtta catttaataa agatggtaaa ctttggacat accaagctag
     5581 atatgtaaaa ctaatctcaa ataataagtc taatatagaa gttgcagaat tagatataat
     5641 aggacctcca ggtgataata tagaaattgg cacaatgaat aatgtagacc aaactcgtac
     5701 taatggaatt ggaaagttag cagaagatta tgtatatcaa agtgatgacc ctagcacaag
     5761 tgaagacgaa acaggtaaga ttccagcagg ttcaataatt attacaggtg aatacagtgg
     5821 aaatccagca tttaatttac cactacttat agataaaaac aataagacta tatctggaga
     5881 agcactttta tttgcagaag ttccagaaaa aggtgaatta ggtgaaatca gtaaaggtac
     5941 atgggtttac tatatgccaa aagaaaactt tgattcttta agtgataagg ttaaggctga
     6001 actatataga tacaatgacc ttcaaggaga tactccagta ggtcaaagat ttgtaagtga
     6061 tacaatgtat gtacctgtag gagctaagaa ttatgatgag ttaaagacaa taagtcttac
     6121 tgatagtaat agtaaagcta gaaaagctac aagaaatgct attgatgtca gtaataagaa
     6181 ggttataact gtaagcaata aagtaaaggg taatattgtt agagataaat agtaggtgga
     6241 actctaaaaa cgtaaaaata ctaatactaa cattgtatat ctaatatgat taggtactag
     6301 aatagtttta aaatagtaga tattaaaagc aaagtatata aatgtaacta taagtttagg
     6361 gtaatttata aattaaatat aaaagctagg tggataagta aatttatcca cttagttaat
     6421 gatagataag gacgggtgtt aatgagtaaa agaaaatctt ttataagaac tatagcagta
     6481 tcaactatgg cagtagctgt aactggtagt gctacatgtg catatgcagc tccagtttta
     6541 caaggaagaa aaacgtatga gaaagtaaat actatagata tatctgtgga ctcagtagaa
     6601 aacatagtat attcatttca agccagtata aaagtacaag gtgaggttga agtagtagat
     6661 aatgagcaga aagaaaagat tacttggtct gataatataa aatctcagat aaaaagtgga
     6721 aatgcaaatg ctacttgtag agcagaatac aacaaatcaa gcaatacaac tacattagat
     6781 atatatgtta catcaaatga agatttatta gacggaaata gattgaatat aggaagaata
     6841 tctgtaaaaa aatctggcag taactcaaat gctgactata aagttttagg aaaaggaaca
     6901 agtgataaac cagctttaaa aattgtaaca tataacaaca aaacagtgga ttatgaaaat
     6961 ataaactctg atgaaggatt aatatttacc cttattaatg agagtgaagt aaaaccgatt
     7021 ggtggaactg gttctagtaa aaatgaccct gaaaagtata aggtagagaa aagtgaagca
     7081 cttgaatatt tattaaacaa tattaggata aactattcta ttgttagtaa agaaacacaa
     7141 gaaagtggtt ccaatgtaat attaaaactt ggattagcac aaaaaacaac taagggaaga
     7201 aaaactacaa taaacaaata tgttgaagtt acacttccaa aaagtttaga atacatagtt
     7261 gaaaatgaat tatcaaaacc ggatgaatta ccaccagata atggcaatgg tggaaataat
     7321 ggtgctggaa gtaattcagg cggttcgtct agtggtggaa gttctggagg aggaagttca
     7381 agtaattcta catctaatgt cacagtcaaa aaattaaaag gtgctgatag atttgagaca
     7441 gctaccaaaa tatctcaaag tggttggaca aaatcagata cagttgtaat agtaaatgga
     7501 gaagataaaa gtatggtgga tgggcttaca gctacaccac ttgctagtgt aaaaaactca
     7561 ccgattcttt tatcatcaaa tgaaaagctt cctcaaaaaa ctgtagaaga attgaaaagg
     7621 ctaaatccat caaaagtaat tgtgataggt ggaaacaact caatgccaaa ttcagttgtt
     7681 gaagctatca aagctgtaaa ttcaaaaata tcagtacaaa gaataggtgg agatacaaga
     7741 tatcaaactt ctattaatat agcaaaagaa atagataaga cgaataatgt aagcaagttg
     7801 tatatagggg caggaaatgg agaagctgat tcattatcaa tagcatcact ggctggtaaa
     7861 gaaaaaactc caatagtact tacacaaaaa gatggtgtag ataatgaagc tgtacaattt
     7921 attaaatcaa ataaggtgtc aaatatatac tttattggtg gaatagaaaa aatatctaac
     7981 aaggctattg aacaagttgg aaaaatagta aacaaagata tatcaaacaa tagggtggca
     8041 ggtcaaacta gacaagagac gaatgccaaa gtaatagata aattctactc tcaatctaaa
     8101 ctagatggag ttgtggttgc aaatcaagat aaacttatag acgctttagc agttggacca
     8161 ttagcagcta aaaacaattc accagttata cttgctacaa atatgttaga taaatcacaa
     8221 gaatcgtcat taaaaggtaa aaattcatca aagttgtttg aagtaggtgg aggaatagcc
     8281 tcatctgtaa tagataagat taagagttta attgaaaaat aaatattaag taaatagaaa
     8341 ataagaatgt atttagatat aaagttatat atttagatgc attcttattt tattttcatt
     8401 atcttaacaa tttaataata ttgaggttaa aatgtataat aatttgagct atattaagtt
     8461 taattttaaa taaagcagat atcttttata tatataaata taaattcaat tttgaatatg
     8521 tttaaaaaga agttaaaaat aattttttaa atttaataaa ataaaacact aatatataga
     8581 cgagatatat tcatatcata tatactctat aatatatgga aaataaagag aaaataaatg
     8641 gaaaataatc gcaatataaa tataaaatat aaaaatcatc agggggatat gaaaatgaac
     8701 aaaaaaatat tatcattagg tctagcagta tcattaatct tagtaaactt caaaagtgta
     8761 aatgcatcat cagtagtaga aaaaatatac ggtaaagata gatatgaaac agcagcaaag
     8821 atagctgata aacagactta tgaaacagta attttagtaa atacagaaaa atcacttgca
     8881 gatggattaa gtgcaagtgg attatcagga gctacaaaag ctccaatact atttacacaa
     8941 aaaaataaga taccagcaga cacaaataga tgtctaaaaa atatcaaaaa agcatatata
     9001 ataggtacag aagatactat aagtaaatca gtagaaaaag aactagattc taaaaatata
     9061 gaagtcaaaa gaattggtgg agaagataga ctaaaaacaa gctatttaat agctaaagaa
     9121 atagcaacta taaaaaaagt ggataaagta ctattaacta acgcatatag tggagaagca
     9181 gacgcaatga gtgtatcatc agtagctact agagatggag ctccaatcat acttacagat
     9241 ggaaagagtg tgccttttga tgtaaaaaac attcaatcat attgtatagg ttcagaggag
     9301 ataatgagta accctctagt taaaaataca aactcagtaa gaatagaagg aactgaccga
     9361 tttgaaacta acaaaaatgt aatagactac ttttttaata gtgcagatgg attctatgta
     9421 tcagatggat accaattagt agatgcaata gcagctgcac cacttactaa aaactctcca
     9481 atggtactag taaatgatgg aagcgataaa actgtattag aaggagctaa gaatataact
     9541 tctgtaggtg aaataaatga gaaggtaata caacagtgta taaatgcttc aaagtcaaat
     9601 ggacaaccac caacaattac agttggaagt acagagatat ataagggtga aaagtttgac
     9661 actggcaagt taaatatagt ggctaaagat aacactggga aggtattacc aatagaagtt
     9721 gatgggttta tagatacaaa tagagtaggt acatacatat tgacattaaa agctacagac
     9781 gaatggggaa aaagtacagg aaaaagaata gaaataaaag tgttggatga taaatcttat
     9841 gattacaaca gcccagaatt taaaaaaatg gtatctactg aaatgtataa cttaatcaat
     9901 tcctatagaa aagaaaaagg caaagagcct ttggtagtat ctagtaggct agaaggtatg
     9961 gcaaatgcat ggtctaagta tatgatggat aaaaaagtat ttgcacatta tatagatgga
    10021 aaaaatgctc cacaagtatt ttctgagttt ggaatgagaa gtgaggaaaa tatagcatat
    10081 atttatatag attctaagaa cgttcaaacc acacaagatg caaaagactt ggcaaaggct
    10141 atatttgaag tgtggaagaa atctccagaa tacaatgcaa acatgcttag taatgagttt
    10201 tatagtactg gatttgggct ttatatatta tctgatggtc aagtgcatgc tactcaagag
    10261 tttttaaatg gcaatgaagg tagcttgtaa aaaattccat aaatcttgtt tttttgttaa
    10321 tttactgata ttataaaatg aaaatcacat ctaaagtact ttttgtaatc tgttttgtta
    10381 ttgctttaca ggttatggta ttttaggtgt tttttgtttt agtagtttat aaattttgag
    10441 ggaatcacta ctgaggatgt aatttatgat tagctgaatt atataaaaaa attagtagga
    10501 ggagttcgat gaaggtaaat aagagagtat tatcaatagg attggcaata tcattaataa
    10561 tggcaggagc accaaatatc aatgcacttt cgagtataga aaagatacaa gggaaagata
    10621 gatatgagac ttctgcattg atagcagata aacaaatata tgatacagtc atattagtaa
    10681 atactgataa ttctatagta gatggattaa gtgcaagtgg attatctgga gttgtaaaag
    10741 ctcctataat gttggtgcaa agagataaga taccaacaga tgttgaaaaa agactaaagg
    10801 atgttaagaa tgcttatgtt ataggtacag aggatacaat aggtaaatct gtagaaaatc
    10861 aacttaagaa taaagggatt gaagttaaaa gaattggtgg ggaagataga ataaagacta
    10921 gctatcttat agctaaggag atttcagcta ttaaaccagt aaatgatggt gataaggttt
    10981 tccttgtaaa tggatacaca ggtgaggctg atgcaatgag tgtatcttct gtagctgcta
    11041 gagatggagt tcctgttata cttactgatg gaaagagtat accatttaag gctgatggcg
    11101 ttcaatgtta ttctcttggg tcagaggaga taatgagtaa tgaacttgtg agtaagacta
    11161 attctgttag gattgctggt aaggataggt ttgagactaa taagaaggtt atacaacgct
    11221 tttataaagg aacaaataaa ttttatgttt ctcaaggata taaattagta gacgctgtag
    11281 caggttctcc attagctaaa aatagaccta tagtacttgt tgatgataga agtgataaga
    11341 gtatacttaa aggagcagta gaagttactt ctttaggagg gatggataaa aaggttattg
    11401 aacaatgtat tgattatgca tctgataaga atacattgcc tacaataact gctaataata
    11461 ttgaaatatt tgtaggagat agttttaata atagcatgtt gaatatagtt gctactgatt
    11521 atcatgggaa tgaattaatt cctaatattc aagggaaggt tgatacaaag aaagcaggtg
    11581 catatatttt aaatatatat gctatagata gtttaggtca gaagtgtgaa gttagtgtaa
    11641 atgtaaaggt tattgtaaat acaagtacaa aagaccctaa tagttatgag tttaaggcta
    11701 tggtgaccaa tgagatatat aatttagtta attcgtatag aacagaaaaa ggcaaaaagg
    11761 ttttaaaaga atcaaaatca ttatctggaa tggcaaatgc atggtctaag tatatggatg
    11821 agaagaaagt atttgctcat gagattgacg gaaaaaatgc agcggaagtg ttttttgggt
    11881 ttggagcaag aagtgatgaa aatattgcat atttacctat gaatgttaag tctgtttata
    11941 cttctaaaga tgcaaaagaa atagctaaat ctatttttga tttatggaag aagtcttcta
    12001 agtacaatga gagtatgcta aaagatgagt tttatagctt tggatttggc atgcatgttt
    12061 ctagtcaagg tgaagttaat gcgacgatgg agtttttgaa tagttagatt ttatattagt
    12121 atctatgata ataaggtttc aaagttaact taaacactta gtaaaattaa aaattcgtga
    12181 tattttgtaa aaatgatttt aaaaaaataa aattagcaaa aaaacagata atttgttgga
    12241 aaaaacttca attaattttg cataaattat tgaaattata ttttatatag tctatcataa
    12301 gagtgtgaga aatatttgga ttatatgaac atggaaattt aatgtacata attaaagaga
    12361 tgtaattaat ataatgttgg gaggaattta agaaatgaat aagaaaaatt tagcaatggc
    12421 aatggcagct gttactgtta taggttctgc tgctccaata tttgctgatg gtactgctgt
    12481 taaagaagaa ggatatacgg tagttcaaga caaatatgaa aaattactta aagaattaaa
    12541 agcaaaaata aacgatggaa ctattacatc agttggtgtt gaattcgatg gaagttcaat
    12601 tggaactgtt gctcctacta gtgacagtac tgcagataaa aaaacagctg ctgacaagtt
    12661 agaaacactt actaaaaacc aacttaaagg tttaggtgat ggaaagtacg tagatttcaa
    12721 aattacttat ggcgctaaag ctgaggttcc agctgctaca ttaagtgcag aggatataca
    12781 aaaatatgca gatcaaataa atgcttctac tacaaaatta gttgatgtag ctgggagtga
    12841 agctggtata gctacatttg atagtgctaa ctctaaaata gtaccaggag ctgctcctct
    12901 tactattaaa gatgcagtaa aggctacagt tagtgaaagt ggtggtaaga aacttcttac
    12961 aataacagct gcagatacat tagttaattt taaatatggt gaacttaagg gatctggtgc
    13021 aaatggaagt gaaatagaag caataactct tggaacttca gatttaacag taacagaagg
    13081 cgataataaa aaaatagatg tagataaatc atttgcattt gacaaatcta ctaaaaaatt
    13141 agctggttta agcttaacaa ctacagaaaa aactcctgca gatccaggtt ctacaattac
    13201 tgttagagta ataaaagctg tagaaaaaac aatagatgta agttcaagtt caactacaaa
    13261 agctaaagat ttagctaaac aatatgtatt cacagatgtt agtgatactg atccagaaag
    13321 tttaagttat atgcttaaaa atataaatga tggaaaagta gctgtgaaaa attctgatgg
    13381 agattgggaa gtaactatat tcccagaagg aaaaagatta aatactttat ctgcatcttc
    13441 aacaaaaact attttaggag acaaagatac tccagcaaaa atagttttaa aagcttcaac
    13501 aacaaaaaaa atagcagact atatagatga tttaataact tataacaata gttattcaaa
    13561 tgtacaaact gtagcaggta gtgatagaat agaaactgct atagaattaa gccgtaaata
    13621 ctataactct actgataaaa atgctttata tgaaaatcct gtagataacg ttgtattagt
    13681 aggttctcaa gctatagttg atggattagt agcatctcct ttagcagcag aaaaaggtgc
    13741 tcctctatta ttaagttcta aagataaatt agactcagca acaagagctg aaataaaaag
    13801 agttatggat ttaaattctt caactggaat aaaaaataac aaagaagttt atttagctgg
    13861 tggagtaaat tctatatcta aagaagttga aaatgaatta aaagatatgg ggcttaaagt
    13921 aactagatta tcaggtgatg atagatatga aacttcatta gctatagctg atgaaataga
    13981 cataaatgat aaagcttatg tagttggtgg aacaggatta gcagatgcta tgagtattgc
    14041 accagttgca tctcaaataa aagatggtga agctacacca atagtagttg tagatggaaa
    14101 agctgacaag ttatctaaag aagctgaaga tttcttagat gatgcacaag tagatataat
    14161 aggtggagaa aacagtgttt ctgctaagat ggaagattat atagatgatg ctactggaaa
    14221 atctccagaa agaattagtg gtgctgatag acaagcaact aatgctgaag ttataaaaga
    14281 atactttgat aaagataaag tttcaaatta tttcttagca aaagatggtt caactaaaga
    14341 agatcaatta gttgatgctc tagcagctgc agcagtagct ggaaactatg gctctaaaca
    14401 taatgcagat ggagctataa ctacagaggc ttctcctgct ccaattattt tagcaactga
    14461 taatttatca gctgaacaac atgtagctgt aagcaagact gctactacta gtggtgctaa
    14521 gaatttagta caagtaggtc aaggaatagc tgattcagtt gttagtaaat taaaagattt
    14581 attagatatg taatataaat tttatatatt gaataaaaag gtttctcttt tgagagacct
    14641 ttttttattt gagtgtaaat tttataaata aaaaagaggc taaattagcc tcttttcagt
    14701 gtgagaaata cttaaaaaat aagatgtaat tatttattta agtatcatca ttatactata
    14761 ccttaaaata aatgtctact attccattat tttaaggtat aatagtaagt ggaaaataaa
    14821 ttaggaggta aattaattat gtcagtttta gatgtaatac tagacaaaaa agatgaatta
    14881 gaaattaaaa aattaaataa tatagtagat aaaatagacg aattagaaaa tgaaatacaa
    14941 gtattagatg atgaagcatt aaaaaatatg acaaatgtgt ttaaggatag gttaaataaa
    15001 ggagaaactt tagatgatat attgccagaa gcttttgctg ttgtaagaga agtatcaaga
    15061 agaatattag gtatgcgcca atatagagtt caattaattg gtggtattgt gttacatcaa
    15121 ggaaaaatag cagaaatgag aaccggagaa ggaaaaactc tagtgggagt agctccagtt
    15181 tatttaaatg cattgacagg taaaggtgta catgttatca ctgttaatga ttacttagct
    15241 caacgtgata aagaacttat gcagccagtg tatgaatttt tagggttaac agtaggagta
    15301 attattaatg gacaagaacc agtagaacga aaattgcaat accaatgtga tattacttat
    15361 ggtacaaaca atgagtatgg atttgattat ctaagagata atatggtaac aagagagata
    15421 gataaagttc aaagagaact aaactttgct atagttgatg aagttgactc aatacttata
    15481 gatgaagcta gaactccact tataattgct ggagaaggtg atgaaggtac taagctgtat
    15541 gaacttgcaa atgcttttat aaaaactata aaagatgaag attttgaaat ggatagaaaa
    15601 gataaaacaa tagcacttac tgcaagtggt cttagcaaag cagaaaaatt ttttggaata
    15661 gaaaatataa ctcacataga taatatagag atatttcatc atgtaaatca gtctttaaga
    15721 gcacataaat taatggacat agatgttgaa tatgttgtta gagataatga aatattaatt
    15781 gtagacgaat ttacaggaag aataatggat ggaagaaggt ttacagatgg tcttcaccaa
    15841 gcaattgaag ctaaagaagg tgtaaaaata aatgatgaat caaagactat ggcaactgta
    15901 acttttcaaa atttctttag gctatattct aaattatcag gtatgacagg tacagcgaag
    15961 actgaagaaa gtgaatttga agatacatat aagattaatg ttgttcagat acctactaat
    16021 aagcctgtta taagagctga tttgcatgat aaagtgttta aaacagaacg tgcaaaatac
    16081 aatgctgttg tagaagaaat aataagaata aatgcaacta aacaaccagt acttgtaggg
    16141 acagtttcaa ttgaaaaatc tgaaaaacta tctaaactgc ttaaaaagaa aggtgtaaaa
    16201 catgaagtct taaatgctaa acaacatgat aaagaagctg aaataatatc taaagctggt
    16261 aaattaggtt ctgttacaat tgctactaat atggcaggta gaggaacaga tatatcactt
    16321 ggagctggag ataaaataga agaagaaaag gtgaaagaat taggtggatt atatgttata
    16381 ggtactgaaa gacatgagac aagaaggata gataatcagc ttagagggcg ttcagggaga
    16441 caaggagacc ctggaacttc tagattcttt gtaagtttag aagatgaagt aataaaatta
    16501 tatggtggaa aaagtataga aaagatatta aagagaatga atgcaaatga agatgaagca
    16561 ctagagagta agtctttaaa tcgagctata gaaagagctc aaaaaggtat tgaaggtaaa
    16621 aactttgaac aaagaaaaaa tgttcttaaa tatgatgata ccattaatga acaaagaaaa
    16681 gtaatatata atgaaagaaa taaggtattg agtggctcag atattgaaga tgagatacaa
    16741 aaaatggtta tggatatcat ctcagatgct gccgaaaaat atctgaaaaa aaatagagat
    16801 tatcatggat attttaaata tctatataat acttttatgc cagcagatac actattaatc
    16861 ccaaatttag atgaaaagag tgttgaggaa ataataagtc aaacttatca aatttcaaaa
    16921 cgtgtttatg accttaaaaa aatgatggtt ggaattgaag aattagcaca attagaaaaa
    16981 agagtattac ttcaagttgt ggatacttat tgggttgatc acatagatgc tatggaccaa
    17041 ttaagacagt atataggtct taagtcctat gcacagaaag atccttttaa agaatatgct
    17101 atagaaggtt atgatatgtt tgaagcttta aataagaata tcagagtaac tacagtgcaa
    17161 tatctatata aatttaacta aaaaagtgac cttctaggtc acttttcata tattaatatc
    17221 atagtataat ttattttata attatagcac ttgtaaataa aaatttatat taatgaaaaa
    17281 gaggctgaac gtcagcctct ttttctgtgt gagaaatacg gaaaaaagag atgcttgaaa
    17341 tttctttctt ccatttaata ttatactata aagataataa aaagtctatg agttatatat
    17401 atgattaaaa aaaaaattta caattttgtt actttttagt atacaaaaat aaatttaact
    17461 taatatttat caattatact taatgaaata tctaaatatt acaatatcta cagtttattg
    17521 aaataatatg taaattatat tataattggt aaataaggaa aaaatgatga aaaactgaat
    17581 tttttagggg gaaaatgtat gaatagaaaa ggtctttctg taattatagc agctgcaatg
    17641 gtaagtacat cagtagctcc aatttttgct gcagaaacta cacaagtaaa gaaacaaaca
    17701 ataactaaaa aggaagcaac agaattagtt tcaaaagtta gagaactaat ggctcagaga
    17761 tatacaggag gttctcaagt tggacagcca atatatgaaa taaaagttgg cgagaattca
    17821 tcaaaattaa aagtaataac taacatagat gaattagaga aattagtaaa tgctctagga
    17881 gaaaataaag agcttattgt tactatctca gacaaagggc atgtaacaaa tagtgcaaat
    17941 gaggtagttg ctgaagcaat tgaaaaatat gaaaattcag cagatctttc agctgaagct
    18001 aattcaataa cagaaaaggc taaagctgaa gctaatggaa tttatggtgt ggcaactgta
    18061 gaagcttcat atgatagtac aagagataag ttagtaataa ctttaaaaga taagacagat
    18121 gtaataactt ctaaaacact agaaataggt attggtgatg aaaaggttga tttaacagta
    18181 aatccagttg atatagcagg aacaaattta gacacttctg cagaaggatt tagagtaaat
    18241 aaaattaata aattaggtgt agctggggct aaaaatattg atgatattca attagctgag
    18301 ataactataa aaaatagtga tttaaataca gtttcaccac aagatttata tgatggatat
    18361 agattaactg ttcaaggtaa tacaatagca aatattgcag gaaaattaat tagtgatatt
    18421 tcagcaaaag attcagaaac aggaaagtat aaatttactg ttaaatatac tgatacatct
    18481 ggaaaagcga tagaacttac tgtagaaagt actaacgaga aagagttaaa agatgttaaa
    18541 gctgcattag atggaaatac aaaagttaat ctaatagctg gagaagatag atattcaact
    18601 gctgtagcta tagcgaaaca aacaaaatac actgataatg tggttatagt taattcaaat
    18661 aaactagttg atggattagc agcaacacca ctagcacaat ctaaaaaagc acctatatta
    18721 ttagcatctg ataatgaaat accaaaagta actttagatt atataaaaga aataattaag
    18781 aaaagtccat cagctaaaat atatatagtt ggaggagaat cagcagtatc aaatacagct
    18841 aaaaagcaat tagaatcagt aactaaaaat gttgaaagac tagctggaga tgatagacat
    18901 acaacttctg tagcagtagc aaaagctatg ggttctttta aagatgcatt tgtagtaggt
    18961 gcgaaaggtg aagctgatgc tatgagtata gctgctaaag ctgctgaact taaggctcct
    19021 ataatagtaa atggctggaa tgatctctca gcagaagcta tccaattgat ggatggaaaa
    19081 gagattggca tagttggtgg ttctaacaat gtatctagtc aaattgaaaa tcaacttatt
    19141 gatattgata aagatagaaa agttcaaaga gttgaaggag aaacaagaca cgatactaat
    19201 gctaaagtta tagaaacata ttatgacaaa ttagataagt tatatatagc aaaagatggg
    19261 tatggaaata atggtatgct agtagatgca ttagcagctg ggcctctagc agcaggaaaa
    19321 ggaccaatac ttctagctaa aactgatata acagattcac aaaagaatgc tcttgataaa
    19381 aaattaaatc ttggtgcaga agtaactcaa ataggtaatg gggttgaatt gactgtagta
    19441 caaaaaatag gcaaaatact aggatggtaa taatcaacaa tgtagaaaag gattccttat
    19501 tatattatag gaatcttttt ctatcgacat aatatacttt aaagtataac atgttcttga
    19561 cagataggag gatataatag tgatagaagc aacattgttt ttttccccac accaagatga
    19621 tgaaacatta agtatgggta gtgcaataat tgaacatgta gaaaaaagtg atacacatgt
    19681 tatattatgt actgatggta gtaagtcaat aataagaaaa gttttagatg atggaggtac
    19741 atgttcttat catattaaag atgtgcataa atattctcta tcagaaagtg atttttcaaa
    19801 aaatagagat gaagaattta aagatagttg taaagcaatg ggagtcaaag aaaataatat
    19861 acatatagag aataacagag ctcatgatgg agaattaagt aaagaaaaag caagagatat
    19921 aatactaaaa tatttagaaa aatatcctga tgctaaagtg aagacagtta caccatataa
    19981 agctcttgga atacatgaag atcatagagc attaggtgaa gctgcattag aattgtataa
    20041 agaaggaaaa ataaaagatt taagatttta tgtagaacca tatgattata atgatttcaa
    20101 aaaagttaat ccaaatgtta gagtatggaa ggttttgagt agtcaagaag agaaattatt
    20161 aaatgctatg gatgcataca aaaaatggaa ccctgaaaat gggaactacg caattggata
    20221 tcattctgtt aaatctcact ttgatgaatt aaaatccaat aaaattcaat atgtacatgc
    20281 tccataaaca ttaatataaa aactaggagg atatagttaa tgaaaatatc aaagagaata
    20341 atgtcattgt tgacagcaac tttttttatc tttgcattat ctattaatat agctgatgct
    20401 tcatcaaaag agagtctagt aggttctggt agatgggaaa ctgcaataaa aattagccaa
    20461 aatggatgga aagaagctac taatgctata ctagtaaatg ataattctat agctgatgca
    20521 ttatctgcaa ctccatttgc taaattaaaa gatgcgccta ttttattaac tcaaagtgat
    20581 aaattggata gtagaactaa agcagaatta aaaagactag gtgtaaaaaa tgtgtattta
    20641 attggaggaa tgaatactct aagtactaat attgaaaagc aactaaaatc agaaaatatg
    20701 acatttgaaa gaatttcagg aaatagtaga tatgaaacat ctttaaaatt agctgaaaga
    20761 ctagataaag aaaagagtgt ttctaatata gttgtggtta atggagagaa agggttagct
    20821 gatgcagtaa gtgttggttc tattgctgca caagaaaata tgccaattat actttcagat
    20881 cctaataatg gaataaaagt tgcaaataac tttatcagca gtaaaaatat aaagaaatct
    20941 tatataattg gtggtacata ttctgtatct agctctattg aacagagctt acctaatgca
    21001 aaaagattat ctggaaataa tagaaatgaa actaacgcaa aggttgtaga agaattttat
    21061 aaagatacag atttaaaaaa tgcttatata actaaagatg gtatgaaaaa acaaagcgat
    21121 ttgatagatt ctctagctgt aggtgtatta gcagctaaaa atagctcacc agttgtatta
    21181 gtaggaaatg cacttgattc tagccaatat gatgtgttaa atactaaaag ttttgataat
    21241 attgtgcaag taggtggaaa tggaaatgaa gatgctgtaa aggatatact tgatttacaa
    21301 gaagaaacta tatatagagt taagacagca gatgaattag ctgttgctct aagaaaagca
    21361 gatgctaatg atattataac atttaagcct gatgataata aaaaaatcac tagttcattt
    21421 agcatagaaa caaaaaaagc tataactgta gaacttgaag ggctgtatac acaaacaata
    21481 actgtaaata tgccaaatgg agaattaact aataagggta cattagatgg aactgtaaaa
    21541 ataatggata taaaaaatgg tacatttatc aatgaaggtg agataaatga tattgacctt
    21601 tatgattcaa atggatctaa aatagagaat aaaagtggtg gagatatatg ggttttaact
    21661 atatctagta gtgctaaaga tgtaaatata gaaaataaag gtgatataag taaaattaca
    21721 aataattcca ctagtgttat aataaaaaat tcaggaaata ttgatacttt aggtgggatt
    21781 agcacaccat caataagtgg aaataagcct agagttgatg atacagataa agatgaaaaa
    21841 agggcaagtg gaatatatcc tacttcagag cctttatcat ctccaaaacc aggctatata
    21901 aacgtaaaaa tatttactaa acctgaagat acaaattaca aaatttatta cagagtagta
    21961 agtagtagac catctgcatt atatattgga gatagaatag atacaagtga ctggactgct
    22021 gtgccatctt ctgttttacc atttactatt aaagcagaaa atggatatta tatagaagct
    22081 gttgaaataa attctgatac taagaaagta tctagatggg gaaaatctga ctatatagat
    22141 gatggttttt atttaaagtc agaaactgca aaaggactaa gtgcagatat agattttgat
    22201 ggtgattatg taaagctgac agcaacaggt gctgattctg gatgtacagt ttattataga
    22261 atagtatcaa aaaagccagc atcaatgaat gttggagata aaatcactat atctaactgg
    22321 gatgaaatta caactaatag agtaaagata gaagcaaagg atgtaaaaga aaaatatata
    22381 gaattagttg aattagatga ttctactaat aaagttacta gatggggagt aagtgataag
    22441 gtagtagaat aggatgttta acataaaaaa taaaaacaga ctgtatctta attgatta
//
LOCUS       DACTZW010000071        22012 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.071, whole genome shotgun sequence.
ACCESSION   DACTZW010000071 DACTZW010000000
VERSION     DACTZW010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22012)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22012)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22012
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.071"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            277..1317
                     /locus_tag="JAM15_13780"
     CDS             277..1317
                     /locus_tag="JAM15_13780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAT6799325.1"
                     /translation="MDKHSDSVMYGGMEVYNIWGTTTVDSIIGESDVMRALKNRICKI
                     GNSDSTVAITGESGTGKELIARAIHLAGNRGNKTFVAINCAAIPEPLLESELFGYTKG
                     AFSGADSKGKIGKFELANGGVVFLDEIGDMPIQLQSKLLRVLQEKKFTRIGSNELIDI
                     DVRIISATNRDLFELVKENKFREDLYYRLNVIPLEVPPLRERGDDIQILINNFIDKYS
                     RKMKKNVYHIEPDVEQMLLKYPWPGNIRELENTIELALNLLEEDGIIHKGIINRKILE
                     YFKLNNINIKLLEESDYEISMEQDILTLEEFERAYIKKVLKFYGNDTKSKKLAAKKLG
                     ISLATLYRKIDV"
     gene            1646..2995
                     /locus_tag="JAM15_13785"
     CDS             1646..2995
                     /locus_tag="JAM15_13785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HAT6799326.1"
                     /translation="MSKYQKNVSMFDIDGRPPILKCLPLSMQHILAMIVGTVTVPIVV
                     GGAVGVSPTQITLLVQYALIIAGISTLIQLYPIGNIGSRLPIIFGVGFTYVPTLVAVG
                     GNYGLASILGAQLIGGVATVLIGIFIKKIRKFFPNIVAGTVVFTIGLSLYPIAINYMA
                     GGVNSPTYASMQNWAVAAITLVVVIGLSQFAKGYAKLAAIFLGIIVGYCVSLVLGIIN
                     FDPIREATWFAIPKPLEFGMEFDMPVIISVVIVSIINAVQAIGDLSATTMGGMDRNIT
                     DKELSSGVIGSGICTMIGALFGGLPPSSYSQNVGMVAMNKVISRFVLGIAGIFMLLSG
                     FVPKFGALMTTIPYSVLGGATISIFSMITMTGIKLIITEELSSRNITIVGLAIALGMG
                     ITSVPAAQEAFPSFVKLVFGESPIVIATLVAFVLNLIIPNKSLEDEAKERAVMEETN"
     gene            3293..4654
                     /locus_tag="JAM15_13790"
     CDS             3293..4654
                     /locus_tag="JAM15_13790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine permease"
                     /protein_id="HAT6799327.1"
                     /translation="MKTRNTSKYDVDGIPPLKESIPLALQHLLAMIVGNMVPAILIAN
                     VVGLNQGQATMLIQGSMLAAGLATFLQLYPIPLFKGFKLGSRLPVMMGMSYVFLGACL
                     SVAAKDGLAALFGAQIAAGVIVFFVGFGVKKIRHIFTPIVSGTIIACMGLGLFATAIK
                     NLAGGEGTQTFGSPINFTVGVIVAFVIIMINKYGKGLVKNSSILIGILVGYAISLILG
                     LVDFSAVQGAAIVSLPTPAAFGLEFRPELIVMFTIIYIIGIADMMGACTIATVGAMDR
                     EVTDEELASVVLGNSITSIISSLFAALPTGVFSQNTVIVSMNKVTSRFVIALGALVLL
                     LAGISPALGAIMTTIPSCVVGGATLVVFSSIAMSGFSIMSMDGFTEENNLIAGVSIAT
                     SMGLTTAPQVLDQFPETIGTVLGGSSIVSGAIIAILLQTLFKLKSRKSAENVTSNLEE
                     NIG"
     gene            4727..6121
                     /locus_tag="JAM15_13795"
     CDS             4727..6121
                     /locus_tag="JAM15_13795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HAT6799328.1"
                     /translation="MIDILIKNAIIVTVNKDRDVIFDGAIAIQGDRILDIGNTVDIEP
                     KYLDAKKVIDANGKVIFPGFINTHNHLFQVLLKGLGDDMALHEWLNTMMFPSAKFLTE
                     QDTYDAAMLGCMEGLKSGITTMVDYMHTHNRPGLTDGIVKAYKDLGIRGVVGRGCIDL
                     GIHKELIEDVETVEKDLRRVFEKYHNSENGRIKICVAPSSMWAISEEMGKMLWNIVKE
                     YDSYFTVHISETEFARTATKDIHGEIDIKLLEKWGIVGPEVVAVHCVCITDEDMEMLK
                     KYDIKVSHNVASNMYLASGVAPVPEMLKKGINVSLGLDGAASNNAQDMVELMKLTALQ
                     HKVNNCDPLAISAEKVLEMATIEGARTLRMEDEIGSLEIGKKADLVIFNSMLSPKSIP
                     LHNPVSTLVYSASMHNVESVLVDGNVILENGKVTTIESEEQVLLNAQHAAEELCKRAN
                     VTNRMEGHKWNSLY"
     gene            6183..6653
                     /locus_tag="JAM15_13800"
     CDS             6183..6653
                     /locus_tag="JAM15_13800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="HAT6799329.1"
                     /translation="MEKIKLNINDYMYEIEVEKNETLLHVLREKLNLTGAKQGCNSGS
                     CGACKVLIDGVDMKSCKLLAKNCEGKVIYTIESFANGENLHPIQEAFIEVGAVQCGYC
                     TPGMIITTQALLNRNASPNEDEIKEAFKENLCRCTGYVKIIEAVKLSAARLGGR"
     gene            6656..8872
                     /locus_tag="JAM15_13805"
     CDS             6656..8872
                     /locus_tag="JAM15_13805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HAT6799330.1"
                     /translation="MEKVIGKSYPLKDAALKVTGQMKYVADMKPQNVLYAKMLLSPVA
                     HAKIKSIDTSEAEKVVGVRAIATYLNTSQRKYNGSLRFYEHNIPENEVIFSDTVRFVG
                     DRVAAVAAETPEIAEKAVKLIKVEYEELPAVFTIQDAIKEDAICIHGDSNIVSQNNIN
                     GGDVEKGFKECDYIFEDEYSTPAIHHSAIENHSVIAHYDYNDKLTVHTPCQNTFGFRI
                     ILSQIFGMSLNKVRVIRPAIGGSFGGKLELTIEPVAAALSKMTRRPVKMVLTRKESMI
                     STRTRHGSFVKLKTGVNKDGEVIAQDIKIYTNTGAYASSALNVIGALSHKVFKVYKIP
                     NIKFTGMPVYTNTPIAGAMRGYGSPQIFMAQQAQFAKIAKEIGMDLVDFQNKNAVEPD
                     DVDIIFRGSLGNPRVLDCIEQGKKMFKWDEKKKLPKEEGKYLRGIGMAIGAHGNGVFG
                     AHRDVVTLTLKLNEDGTLTLLTGAHDMGNGVVTMQTMMVAEVLGITPDKVDTFETDTD
                     ACTFNLGDYASRGVFVEGGGAKKTAEKLKNLILEEAEKLLETSKEDLYLDNGCVISKL
                     DENVKASLSDIAVYSQSKSLRELTVVEDYSSPAGLTSYGVHFAEVLVDKETKDIKVVD
                     FVAVHDVGRVINPLNLEGQLEGGIHMGLGYALSEELAFDEQGRPKATDFKTYKLFRTV
                     DMPKCQVAFVNSYEKAGPFGGKSIGECAVVPVAPAVANAVYNATDVEIHSLPIKLK"
     gene            8955..9626
                     /locus_tag="JAM15_13810"
     CDS             8955..9626
                     /locus_tag="JAM15_13810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020612977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HAT6799331.1"
                     /translation="MAKILGICGSPRKGATEYAVLEALKEAETIPGIETEYWSVRGKK
                     ISPCVHCDACIRKETMCIIKDDIQELEQKILEADGIIVGSPVYDMNITAQLTAVFNRL
                     RPMYLVHPGKLQNKVGAAITTGGTRYGGQELTKLPIINFFLMHEMLVSGGLGGCYIGG
                     TIWSKDGKAKGAQEDETGMDTVKRLGKGAAEAVMVSKFGLEKWNVVKEELDVKKDEKS
                     PLRDH"
     gene            9989..11203
                     /gene="dpaL"
                     /locus_tag="JAM15_13815"
     CDS             9989..11203
                     /gene="dpaL"
                     /locus_tag="JAM15_13815"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HAT6799332.1"
                     /translation="MLKEIKWKVNNLPKGDKENCIKFLNEEEITKVRNFHKSFPQYKE
                     TPLANLEGLAKKLGVAGVYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLDTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAQEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNHAAAFVSAPDWVSAKGMRTLGNP
                     LNGDEKVISGESGAVTTGLLVAAMEREDLADLRKDLKLDENSRILLISTEGDTDPDKY
                     RSIVWDGEYPSI"
     gene            11330..12517
                     /locus_tag="JAM15_13820"
     CDS             11330..12517
                     /locus_tag="JAM15_13820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgeY family selenium metabolism-linked
                     hydrolase"
                     /protein_id="HAT6799333.1"
                     /translation="MLNEQRKQEVTEICQKLIQNPSSSGNEEGVVKAIEESFEKLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEGKIVDGKIYGRG
                     TSDMKGQYTAMMSAVAYFAKDTNRDFAGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKGVNAVYKMANVIQKIQQLVPPT
                     HPVLGDGILVLTDIKSSPYPGASVVPDYCKATFDRRLLVGETREGVLAPIQALLDEMM
                     KEDPELNAKVSYAVEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYKGLKEAGIDSE
                     ITQYSFCTNGSHYAGEAGIKTIGFGPSKENLAHTIDEYIEQEQLFIGTEGYYGILKSV
                     YGK"
     gene            12650..14020
                     /gene="hydA"
                     /locus_tag="JAM15_13825"
     CDS             12650..14020
                     /gene="hydA"
                     /locus_tag="JAM15_13825"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HAT6799334.1"
                     /translation="MGTILRGGTIITSDKTYISDLRIEDEKIVEIGNNLEINGDKVID
                     ATGKIVIPGGIDTHTHFDMNAGSITTADNFETGTRAAIAGGTTTILDFAEANEGENLL
                     QGVEAYHKKASGNCYCDYGFHMTITCLNKDTFNHMEKLISDGIVSFKMYMAYDGMKVD
                     DGTIYRVLKKARDLGCIVGFHCENGDLLDVLIEENIQNGNLEPKYHPLTRPNIVEKES
                     VSRLADITKLSNSKSYVVHLSCRESLETVKMAREKNIDMIVETCPQYLLLEDNLYNKD
                     KFEGAKYVMSPPLRKKEDINYLWEGLSSGDIQTVGTDHCSFNFKGQKDLGIDDFSKIP
                     NGAPGVEHRLALLYTYGVLENRISVNKFVEVTSTNAAKIFGMYPKKGEIAVGSDADIV
                     ILNINKEETISYKTQKQNVDYTPYEGFKVKCKVEDVFLRGNHVVQSCNVKEHPTGQYI
                     KRKITK"
     gene            14038..15444
                     /locus_tag="JAM15_13830"
     CDS             14038..15444
                     /locus_tag="JAM15_13830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HAT6799335.1"
                     /translation="MMDILIKNAIIVTVNKEREVIFDGALVVKDNKIADIGNSKEIES
                     KYTDVKKIIDAKGKVLFPGFINTHNHLFQTLLKGLGDDMVLKDWLETMTFPAANYLEP
                     KDTYDAAMLGCIEGLRSGITTMVDYMYPHSKPGLCDGIIDAYKELGIRGILGRGCMNT
                     GAQFGVHPGIMQDVETVEKDVRRLFEKHHNTENGRIKIGVAPAAIWSNSQEMLEMLWR
                     VVKEYDDALFTVHISETPFDREAAKELHGQYDIDVLEKLGILGPNVLMVHCVYLTEKD
                     MELTKKYDMKVSHNTASNMYLSSGVAPVPEMLKKGITVSLGVDGAASNNSQDMLELMK
                     LTALQHKVNKCDPLAMSAEKVLELATIDGARAIGMEDEIGSLEIGKKADLLIFNPMLS
                     PKAIPMHNPVSTLVYSSSMKNIESVIVDGNIIMEDSKILTANEEKALKDAQDTAERLC
                     VRGTIKNRMEGHKWNSLY"
     gene            15516..15962
                     /locus_tag="JAM15_13835"
     CDS             15516..15962
                     /locus_tag="JAM15_13835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HAT6799336.1"
                     /translation="MIIKCTINNKEKELSIRPDDFLADTLRENGYVSVKKGCDTGSCG
                     LCTVMVNDKAVLSCNYLTARVDGQHITTLEGVLDEAKKFGDFLADEGADQCGFCAPGF
                     IMMVLAMKRELQNPTEEEVIDYVNGNLCRCTGYKGQLRAIHKYLNT"
     gene            16001..16795
                     /locus_tag="JAM15_13840"
     CDS             16001..16795
                     /locus_tag="JAM15_13840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HAT6799337.1"
                     /translation="MITIKEYVVPKSLDEAYELLISRKNNIILGGCGFLKLGSKNIGS
                     AIDLKDLALDYINETDDSILIGADTSLRTLELNKVIKNYCNGVISNAVSNIVGVQFRS
                     GARVGASVFAKYGFSDLIPSLLVVDAKVKLYKKGVMNLADFLESELEKDILIEVILPK
                     KDAIGVFDSIRKCTGDFAVLNGAMLKEGSIYKIAIGARPRRAKIAYKASEILSLENDI
                     EKAGEVSSEELSFGSNIRGSKEYRKDMAKALVVRMYNSIGGECDGK"
     gene            16785..19076
                     /locus_tag="JAM15_13845"
     CDS             16785..19076
                     /locus_tag="JAM15_13845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HAT6799338.1"
                     /translation="MVNKEVRKIDSEAIVTGKPIYTEDLIFHKDVLTIKLLRSPHAFA
                     KIKNIDTKNALKVKGVVNIFTYKDVPNYRYSMVGESYPEASPHDQLILEDVVRYVGDE
                     VAIIAAEDERAAIKAMKLIKVEYEVMIPILDARESEGNKILIHEEDDLFCPFDFGLDA
                     TKNIVSREKMGKGDVEKEFKESDVIVEHSYMTQSQAHCMMETHRAYTYIDTNGRLVVT
                     SANQSAYHMRRQVSKALGIPLSKVRVIKPRIGGGFGGKNIAVTEIYASFVTWMTKRPA
                     KLIYTREETFAMTNTRHQMFFDIKIGADKEGNIKAIDMKALNNTGAYGDNGPSVCSES
                     GHNVLPTYNNVPAIKFDGRTVYTNLVPGGALRGYGATQGTFALDCAIDELAHKLNMDP
                     TEIKLKNIIKKQTEGGIMNFPIRSCALDECIIRGKKLIGWDEKYPVRDIGNNKVRAVG
                     MSVGTHGSGIANIDMAIVNMRMDEDGTYKLFSGSSDLGTGSDTILAQIAAKALNTSID
                     RISVYTGDTDMCPYDTGAYASCTTYVTGNATIKSAESLKQKILKVAQKKLDLPIDDLI
                     LYEDRVCYSEDVEKFVLLSELGKESVGGGNQEVLYSSESYGIQESAKPFLAGFAEIEL
                     DKTTGEFKVINYACSTDCGTVMNPALARIQVEGGVTQGIGLAMYEDPRHGSDGKLQTS
                     NLLQYKVPTKKDIGNIIVDFVDNYEPTGPYGAKSLGEIVIHTPAPAIANAIYNATGVR
                     IRELPITSEKVYMAMKKLNQGGK"
     gene            19077..20390
                     /locus_tag="JAM15_13850"
     CDS             19077..20390
                     /locus_tag="JAM15_13850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HAT6799339.1"
                     /translation="MIAIKSKYLISSADEIYTNSAVVVENDIIKDILPNEEVEIKYKN
                     IEEIIDKSDAIIMPGFVNGHMHQYGVLSRGIPANVHFTDFEGFLNDYWWPFIENRIGL
                     KEVKATTKASAIELIESGVVAFCDTLEAPNTEEGTLIEQGKILEEIGMKAILSLESCE
                     RISFENGLRCLDENSNLIKWSRENSKLINGIMCTHTSFTCSDRFIKKAKEDAKKLNAP
                     MQFHLCESIYEPNYAEKHFGKKAVDYYNDLDILDETVLASQCVKVNDEEIDILKEKGV
                     KVVHMPLSNCEVGGGFSPVPKMIKKGIKVALGTDGYINDFFEVMRGAFLMHKSVEEDA
                     SVMPANLVFRMATEHGAYVLGLQNSGKIVVGNKADIIVMEDEFKTPVTLDNIFDQIVV
                     QGKKEFISNVYIDGRHILKEKQLVDLDKKAIVKEMKEVACEFWKF"
     gene            20426..21511
                     /locus_tag="JAM15_13855"
     CDS             20426..21511
                     /locus_tag="JAM15_13855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HAT6799340.1"
                     /translation="MYNFLGKELKSPLIIGSGPLTYSAAGCKILSDAGAGAVVTKTIR
                     KERAINPAPHMVRNTTNALLNNEKWTDFEPEQWIDFEIPQMKRDGTVCIASVGHTIEE
                     SSELVEKVANAGADFIELVSYDYRDLIPMLKDAKERVNIPVIVKLPPMIDEIGDFAKK
                     LEEAGADAITACDSVGPAFRIDIETGQPLLGGNGIGYLSGETIKPITLQRIYEIKKQV
                     NIPIIGLGGCVSGDDALEMIMAGADFVGICSVVILKGAQVISKIHDDLKSNLNRLGYN
                     TIENACGIVHNHMGDVNERLSFEFTYDEEKCTKCKMCERVCAYQARKLNDKMELNEEE
                     CRYCGLCISVCKPKALGRKISCSELNV"
     gene            21741..>22012
                     /locus_tag="JAM15_13860"
     CDS             21741..>22012
                     /locus_tag="JAM15_13860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799341.1"
                     /translation="MVMQVQEKILELLYTINEDVVSIKNDMSEVKQEINVLKEDMSEV
                     KQEMTVMKEDMSEVKQEINVLKGDMSEVKQEMTVMKEDISEVKQEMT"
BASE COUNT         8500 a         2449 c         4469 g         6594 t
ORIGIN      
        1 tacgagtagt ataaaaaatt taataagaac ttaaattaaa aattttaaaa attatttcca
       61 tataaaatat ggcattgtaa ttgcttattt aatagaggat ttttgtaaaa tgaagaaagt
      121 atatctatca aattaaaact aagtagatat actttttatt aagttttgtt ttaaaataat
      181 attattaaat tataactaag cttttctgtt atgatataat taaatagata atgtgaatga
      241 ttattatata gaatacttat ttggagttga tattttatgg acaaacacag tgattcagta
      301 atgtatggtg gaatggaagt atataatatt tggggaacaa caacagtaga ctccataatt
      361 ggagagtctg atgtaatgcg tgctcttaag aatagaattt gcaaaattgg aaatagtgat
      421 tctactgtag ctataactgg agaaagtggc actggaaaag aattaatagc aagagccatt
      481 catctcgcag gaaacagagg gaataaaaca ttcgttgcta taaactgtgc tgctatacca
      541 gaacctttac tagaaagtga actttttgga tatacaaaag gagcttttag tggagcagat
      601 tcaaaaggta aaattggtaa gtttgaattg gccaatggag gggttgtatt tttagatgag
      661 ataggagata tgccaattca actacaatca aagttattga gggtattaca ggaaaagaag
      721 tttacgagaa taggttcaaa tgaactaatt gatatagatg ttagaatcat atcagctact
      781 aatagagatt tatttgagtt ggttaaggaa aataaattta gagaagactt atactataga
      841 ttgaatgtaa tacctttaga agtgcctcca cttagagaaa gaggagacga tatacaaata
      901 ttaataaaca attttataga caaatattcg agaaagatga agaaaaacgt gtaccatata
      961 gagccagatg tggaacaaat gttgcttaag tatccttggc caggaaatat tagagagttg
     1021 gaaaatacta tagaactggc attaaacctt cttgaggaag atggaataat acataaaggc
     1081 ataataaata gaaagatact tgaatatttt aagttaaata atataaatat aaagttactt
     1141 gaggaaagtg actatgagat aagtatggaa caagacatac ttacacttga agagtttgaa
     1201 agagcctata taaagaaagt gttgaagttt tacggaaatg atactaagtc taaaaaactg
     1261 gctgccaaaa aacttggaat atcactagct acattgtaca gaaaaataga tgtataataa
     1321 ttaggctttt tattctcaat tctaaaattt gaaattataa aattgataaa aaacacttgg
     1381 agaactattt tctaagtgtt tttttgtgta atagcatttt attatccaaa aataaaaaaa
     1441 atttaaaaga atttaaaaaa ataaatgctt taataaatta tcaaatacta acaaatataa
     1501 taaaaattat atatgtaaaa caattatgtt aaaaaattgg cattataatt gcttcatatt
     1561 aagttgagat gacaaaataa aaaaagaaag gatgttgtgt gagataataa taactgtcat
     1621 taaaaaatag ttgggagtga taaccttgag taaatatcaa aagaatgttt ctatgtttga
     1681 tattgatgga aggccaccaa ttttaaagtg tttgccacta tcaatgcaac atatactagc
     1741 aatgatagtt ggaactgtta cagtacctat agtcgtagga ggagctgtgg gtgttagccc
     1801 tacacaaata acacttttag tgcaatatgc attaataata gctggtatat caacacttat
     1861 acaactatat ccaataggaa atattggttc aagattgcct ataatttttg gagttggttt
     1921 tacttatgta ccaacacttg tagcagtcgg aggaaattat ggattagcaa gcattttggg
     1981 tgcacaatta atagggggag tggctacagt attaataggg atattcataa aaaagataag
     2041 aaaatttttt ccgaatatag ttgcaggaac agtggttttt acaattggat tatctttgta
     2101 tcctatagca ataaattata tggcaggtgg tgtaaatagt cctacttatg cctctatgca
     2161 aaactgggca gtagcggcta taacattagt ggtagttata ggtcttagtc aatttgcaaa
     2221 aggatatgca aaattggcag caatattttt gggaattata gttggatatt gtgtatcttt
     2281 agttctgggt ataataaatt ttgaccctat tagagaggca acttggtttg cgatacctaa
     2341 accgcttgaa tttgggatgg aatttgatat gcctgtaata atctcagtag taattgtaag
     2401 tataatcaat gctgttcaag caattggaga tttatcagct actacaatgg gaggcatgga
     2461 taggaatatc acagataagg aattatcaag tggagtaata ggaagtggaa tttgtactat
     2521 gataggagct ttgtttggag gtttaccacc atcatcatat agccaaaacg tggggatggt
     2581 agctatgaac aaagtaataa gtagatttgt gcttggaata gctggtatat ttatgttatt
     2641 gtcggggttt gtgcctaaat ttggtgcatt aatgactact ataccatatt ctgttttagg
     2701 aggagctaca atatctatat ttagtatgat aacaatgaca ggtataaagt taattattac
     2761 agaagagttg tcatcaagaa atattaccat tgttggtttg gcaattgcct taggcatggg
     2821 aataacatca gtaccagcag cccaagaggc atttccttca tttgtaaagt tagtatttgg
     2881 agaatctcca atagtaattg caacattggt tgcattcgtt ttaaatctaa taataccaaa
     2941 taaaagtcta gaggatgagg ctaaagaaag agctgttatg gaagagacta attaagatat
     3001 aataatttaa aagaattgtt taaattattt agtatgagat tgttagatta tttttgatag
     3061 ctattcattt taataaaaaa tttaacaaat aaatatatac caggtaatta atgtttcatt
     3121 taagttgaaa atcggggagg gaatatttag aaatttgtta attttttata aaaatagctc
     3181 agtttagctg tgtttatcgg ttgagcaata aattcatggt cataaaaata tttatagaaa
     3241 ataattataa aaatatttag tcaagatatt tatgtatggg aggatttatt ttatgaaaac
     3301 acgtaatact tcaaaatatg atgtcgatgg gataccacca ctaaaggaat caataccttt
     3361 ggccttacaa catctgttag caatgatagt aggaaatatg gtacctgcga tattaatagc
     3421 aaacgtggta ggacttaacc aggggcaagc aacaatgttg attcagggtt ctatgttagc
     3481 agcaggttta gcaacgtttt tacagttata tccaatacct ttatttaaag gatttaagtt
     3541 aggttcaaga ttacctgtaa tgatgggaat gagttatgta tttttaggag cttgtctttc
     3601 agtagcagct aaagatggtt tagcagctct atttggagca cagattgctg ctggggtaat
     3661 cgtattcttt gtaggatttg gagttaagaa aattagacat atattcactc caatagtttc
     3721 tggaactata atagcatgta tgggacttgg actattcgca acagctataa agaatttagc
     3781 tggaggagaa ggcacacaaa catttggaag cccaataaac ttcacagtag gagttatagt
     3841 tgcttttgta ataataatga taaataaata cggtaaaggt ttagtaaaaa attcttcaat
     3901 attaatagga atattagtag gttatgctat atctttaatt ttaggattgg ttgatttctc
     3961 agccgttcaa ggagcagcta tagtatcttt accaacacca gcagcttttg gattagaatt
     4021 tagaccagag ttaatagtaa tgtttactat tatttacata ataggtatag ctgatatgat
     4081 gggtgcctgt acaatagcta cagtaggagc aatggataga gaggtaactg acgaagaatt
     4141 agcatcagtt gttttaggaa attctataac ttctataatt tcatcactat ttgcagctct
     4201 tccaactgga gtatttagcc aaaatacagt aattgtatct atgaacaaag ttacaagtag
     4261 atttgtaata gcactagggg cacttgtatt attactagca gggatatctc cagcattggg
     4321 tgcaataatg acaactatac catcttgtgt tgttggtgga gcaactttag tagttttctc
     4381 atcaatagca atgtctggtt tctctattat gagtatggat ggattcactg aagaaaacaa
     4441 tcttatagca ggtgtatcta tagcaacaag tatgggtctt acaactgctc cacaagtttt
     4501 agaccaattc ccagaaacaa ttggaactgt ccttggaggg tcaagtatag tttctggagc
     4561 aataatagct atattacttc aaacattatt taaattaaag tcacgtaaaa gtgctgaaaa
     4621 cgttacttca aatcttgagg aaaatattgg ataaatgtat tagatataat atgagaaaac
     4681 catatggtaa aatgttgtaa tgaaagtatt caaaggggga tttaagatga ttgatatact
     4741 aataaaaaat gcaataattg ttacagttaa taaagacaga gatgttatat ttgatggagc
     4801 aatagctatt caaggtgaca gaatcttgga tataggaaat acagttgata ttgagcctaa
     4861 gtatcttgat gctaaaaaag ttatagatgc taatggaaaa gtaatattcc ctggctttat
     4921 aaatactcat aatcacctgt tccaagtgtt attaaaaggt ttaggtgatg atatggcact
     4981 tcatgagtgg ttaaatacaa tgatgtttcc atcagcaaaa ttcttaacag aacaagatac
     5041 ttatgatgct gcaatgcttg gatgtatgga aggtttaaaa agtggtataa ctacaatggt
     5101 tgattatatg catactcaca atagaccagg acttacagat ggaatagtaa aggcatataa
     5161 agatttaggt ataagagggg ttgtaggtag aggttgtata gatttaggta ttcacaaaga
     5221 gcttatagaa gatgtggaaa cggttgaaaa agatttgaga agggtattcg aaaaatatca
     5281 taattcagaa aatggaagaa taaaaatctg tgtagctcct tcttcaatgt gggctatatc
     5341 tgaagaaatg ggtaagatgc tttggaatat agttaaagaa tatgattcat attttacagt
     5401 tcatatatct gaaacagaat ttgcaagaac agcaacaaag gatatacatg gagaaataga
     5461 tataaaatta cttgaaaaat ggggtatagt aggtccagaa gttgtagcag tacattgtgt
     5521 atgtataact gatgaagaca tggaaatgct taaaaagtat gacataaaag tttctcataa
     5581 tgtagcaagt aatatgtatc ttgcttctgg tgttgcacct gtgccagaaa tgttaaaaaa
     5641 aggtataaat gtgagtttag gtcttgacgg tgcagcaagt aataacgcac aagatatggt
     5701 agagcttatg aaattaacag ctttacaaca caaagtaaat aattgtgacc ctctggcaat
     5761 ttctgcagag aaagttcttg aaatggctac aattgaggga gcaagaactc ttagaatgga
     5821 agatgaaata ggttctttgg agattgggaa aaaagctgac ctagtaatat ttaactcaat
     5881 gctttctcca aaatcaatac ctcttcacaa tcctgtatca actttggtat actcagctag
     5941 tatgcacaat gtagagagtg ttttagttga tggaaatgta atacttgaaa atggaaaagt
     6001 aactacaatt gaaagtgaag aacaagtgtt gctcaatgca caacatgcag cagaagaatt
     6061 atgtaagaga gctaatgtaa ctaatagaat ggaaggacat aagtggaata gcttatacta
     6121 atattaaaat aagattgtaa taatattcta ttacaacatt agtttatctg taggaggaga
     6181 aaatggaaaa aataaaatta aatattaatg attacatgta tgaaatagaa gttgaaaaga
     6241 atgaaactct tttgcatgta cttcgtgaaa aattaaatct aactggagcg aaacaaggtt
     6301 gtaatagtgg cagttgtgga gcatgtaaag ttttgataga tggagttgac atgaaatctt
     6361 gtaaacttct tgcaaaaaac tgcgaaggta aagttatata cactatagaa agttttgcta
     6421 atggagaaaa tcttcatcca atacaagaag cttttataga agttggagct gtacaatgtg
     6481 gatattgtac tcctggtatg attataacaa cacaagctct tttaaataga aatgcatctc
     6541 ctaatgaaga tgaaattaaa gaagctttta aagaaaatct ctgtagatgc acaggatatg
     6601 taaagattat agaagctgta aaattatctg cagctagatt agggggtaga taattatgga
     6661 aaaggtaata ggaaaatcat accctctaaa agatgcagct ttaaaagtta ctggtcaaat
     6721 gaaatacgtg gctgatatga aaccacaaaa tgtactttac gctaagatgc ttttaagtcc
     6781 tgtagcacat gcaaaaataa aaagtataga tacaagtgaa gctgagaaag tagtaggtgt
     6841 tagagctata gctacttatc tcaatacatc acaaagaaaa tacaatggtt cattaagatt
     6901 ttatgagcac aatatacctg aaaatgaagt tatattttca gatacagtta gatttgttgg
     6961 tgaccgtgtt gcagcagtag ctgcagagac tccagaaata gcagagaaag ctgtaaaact
     7021 tataaaagtt gaatatgaag aattgccagc tgtatttact atacaagatg caataaaaga
     7081 agatgctatc tgcatacatg gagattcaaa tatagtttct caaaacaaca taaatggggg
     7141 agatgtagaa aaaggcttca aggaatgtga ctatatattt gaagatgaat actctactcc
     7201 agcaatacat catagtgcaa tagagaatca tagtgtaatt gcacactatg attataatga
     7261 taaattaact gtacatacac cttgccaaaa tacatttgga tttagaataa tactatctca
     7321 aatttttggg atgtcattaa ataaagtaag agttataaga cctgctattg gaggctcatt
     7381 tggtggaaaa ttagaactta caattgaacc agtagcagcc gcattatcaa aaatgacaag
     7441 aagaccagtt aaaatggttc ttacaagaaa ggaatctatg atatcaacaa gaactcgtca
     7501 tgggtctttt gtaaaattaa aaactggtgt aaataaagat ggtgaagtaa tagcacaaga
     7561 tataaaaata tatacaaata caggagcata tgcatcaagt gctttaaatg ttataggagc
     7621 acttagtcat aaagtattta aagtttataa aataccaaat ataaagttta ctgggatgcc
     7681 tgtatataca aatacaccaa tagcaggagc tatgagaggc tatgggtcac ctcaaatatt
     7741 tatggctcaa caggctcaat ttgcgaaaat agccaaggaa ataggtatgg atttagtcga
     7801 ttttcaaaat aaaaatgcag tagagccaga tgatgtcgat ataatcttcc gtggttctct
     7861 tggaaatcct agagtattgg attgtataga gcaaggtaag aagatgttta agtgggatga
     7921 aaagaaaaaa cttccaaaag aagaaggaaa atatttaaga ggtataggta tggcaatagg
     7981 tgcacatggt aatggagttt ttggtgcaca tagagatgtt gttacattga ctcttaaatt
     8041 aaatgaagat ggtacattga cactactaac aggagcacat gatatgggta atggtgtcgt
     8101 aactatgcaa acaatgatgg tagctgaagt tttaggaata acacctgata aagttgatac
     8161 atttgaaact gatacggatg catgtacatt caaccttggt gactatgcaa gtagaggggt
     8221 atttgtagaa ggtggaggag ctaaaaagac agcagagaaa ttgaaaaatc ttatattaga
     8281 agaagcagaa aaattacttg aaacatcaaa agaagattta tatctagaca atggatgtgt
     8341 aattagtaaa cttgatgaaa atgtaaaagc atcactttct gatatcgcag tatatagtca
     8401 aagtaaatca ttaagagagt taactgttgt tgaagattat tcttcaccag ctggacttac
     8461 ttcttatggt gtacattttg ctgaagtttt agtagataaa gaaactaagg atataaaagt
     8521 agttgatttt gtagctgtac atgatgttgg tagagttata aatcctttaa atttagaagg
     8581 tcaattagaa ggtgggattc atatgggtct aggatacgca ttgagtgaag aattggcatt
     8641 tgatgaacaa ggtagaccta aagctactga ttttaaaaca tataaattat ttagaactgt
     8701 agatatgcca aaatgtcaag ttgcatttgt aaatagttat gaaaaagctg gaccttttgg
     8761 tggtaagagt attggagaat gtgctgttgt accagttgcg ccagctgttg caaatgcagt
     8821 atataatgca actgatgtag aaatacattc attgccaata aaattaaaat agtagaaatt
     8881 aaagcacaaa caacaattta ttgtatttgt aaatagataa taaaaataga tttatttggt
     8941 gaggagatat tattatggca aagatattag gtatttgtgg aagtccacgt aaaggagcaa
     9001 cagaatatgc agtgttagaa gctttgaaag aagcagaaac tatacctggt atagaaactg
     9061 agtattggtc agttagaggg aaaaaaataa gtccttgtgt acattgtgat gcatgtataa
     9121 gaaaagaaac tatgtgtatt ataaaagatg atatccaaga attagagcaa aaaatattgg
     9181 aggcagatgg aattatagta ggttctccag tttatgatat gaatataact gctcaactta
     9241 cagcagtatt taatagactt cgtccaatgt atttagttca tccaggaaaa cttcaaaata
     9301 aggttggtgc agctataact actggtggaa ctagatatgg tggccaagaa ttgacaaaac
     9361 ttcctataat aaatttcttc ctaatgcatg aaatgttagt atctggaggt ttaggtggat
     9421 gctatatagg tggtacaata tggagtaaag atggaaaagc aaaaggtgcc caagaggatg
     9481 agacaggtat ggacacagta aaaagacttg gaaaaggtgc agcagaggca gttatggttt
     9541 ctaagtttgg tcttgaaaaa tggaatgtcg taaaagaaga attagatgtt aaaaaagatg
     9601 aaaaatcgcc tcttagagac cactaaagat ttattatatt attgaatata tacaaatagt
     9661 gatgtaatag attattgcat cactatttta tgttttaatt tagattttat agattttata
     9721 ttaaaaaata tagaaacaaa gtgttttgag atttattttt aaattttaaa aatgagaatt
     9781 aaaaagtgag aagatagaaa aggtttttta gttattaaat tctacataca ttgtatgaac
     9841 taaagataga aaagaaaaaa taataaaagc attgcaattt ctatactaaa gagtcataga
     9901 aaaatatcta gtatatattt agtgttggca tgttaattgc ttatatatta aagtataaaa
     9961 atttaacaat aatttggagg tattttagat gttaaaagaa attaaatgga aagtaaataa
    10021 tttgccaaag ggcgataagg aaaattgtat caaattttta aatgaagaag aaataactaa
    10081 ggttagaaat tttcacaaaa gctttcctca atataaagaa actccattag caaacctaga
    10141 aggtttagca aaaaaattag gtgttgcagg agtatatgta aaagatgaat cttatagatt
    10201 tggattaaat gcatttaaag tattaggtgg ttcttattct atgggtagat acttagctca
    10261 aagattagat acagatatat ctgagttagg gtatgacaaa ttgacttcga aagaaataaa
    10321 agaaaaatta ggagaaataa ctttctttac agctacagat ggaaatcacg gtagaggagt
    10381 tgcttggaca gctaataaat taggtcaaaa atctgttgta ttaatgccaa aaggttcttc
    10441 tgaatttaga ttaaataaaa tcaaaggaga aggtgcagat gctagtataa cagacttaaa
    10501 ttatgatgat gcagtaagat tagctaatga ttatgcagaa gctgatgacc atggagtaat
    10561 ggttcaagat acagcatggg acggatatga agaaatacca gcgtggataa tgcaaggata
    10621 tggaactatg gctcaagaag ctatagagca attaaaagaa tatggagtag atagaccaac
    10681 acacgtattt gttcaagcag gagttggttc acttgctggt gcagttcaag ggtatgttgc
    10741 ttcaatatat gatgaatgcc caataacagt agtagtagag gctgatgaag ctgattgtta
    10801 ctataaatca gcagaagctg gagatggaaa accaagattt gttggaggag atatgccaac
    10861 tataatggca gggcttgctt gtggagaacc aaatactata ggatttgaag tattaaaaaa
    10921 tcatgcagca gcatttgttt cagcaccaga ctgggtttct gctaaaggta tgagaacatt
    10981 aggtaatcct ttaaatggtg atgaaaaagt aatttctgga gaatctggag cagttacaac
    11041 tggtctttta gtagcagcta tggaaagaga agatttagca gatttaagaa aagatttaaa
    11101 attagatgaa aattcaagaa tacttttaat aagcacagaa ggagatactg accctgacaa
    11161 atatagaagt atagtttggg atggagaata tccaagtata taaggaatta ctaaaatgca
    11221 attattagat attggtttac atatttagaa gatatataag ttctaaaatt tagaaaatat
    11281 ataagtatat aaaatacata cattataaaa aatctagggg gataatgaaa tgttaaacga
    11341 acaaagaaaa caagaagtaa ctgaaatatg ccaaaaatta attcaaaatc ctagttcttc
    11401 tggaaatgaa gaaggtgttg taaaagcaat agaagagtct tttgaaaaat taggttttga
    11461 tagttggtca agagatagat atggaaatat agtaggatgt ataaaaggta acaagccagg
    11521 taagaaaata ttatttgatg gacatataga tacagttcca gttccagatg caagtaaatg
    11581 gagtgttcct ccttttgaag gaaaaatagt tgatggaaag atatatggta gaggaacttc
    11641 tgacatgaaa ggtcaatata ctgcaatgat gtctgctgta gcgtattttg ctaaagacac
    11701 taatagagat tttgctggag aactatatgt agcaggtgtt gttcatgaag aaatatttga
    11761 aggtgtttcg gctagagaga taagtaaggc tgttcaacct gactatgttg taataggtga
    11821 gtcttcagag ttaaacttaa agattggtca gagaggtaga ggagaaatag tagtagaaac
    11881 ttttggtaaa ccagctcact ctgctaatcc agaaaaaggt gtaaatgcag tttataaaat
    11941 ggctaatgta atccaaaaga tacaacaatt agtacctcca actcatccag ttttaggtga
    12001 tggaatatta gttttaacag atataaaatc ttctccatat ccaggagcat cagtagtgcc
    12061 agattattgc aaagctactt ttgatagaag attattagtt ggagaaacaa gagaaggcgt
    12121 attagctcca atacaagctt tattagatga aatgatgaaa gaagacccag aattaaatgc
    12181 aaaagtttct tatgcggttg aaaaagctga ttgctataca ggaaatacta tagaaagtga
    12241 aagattcttc ccaggttggt tatatgacga agaagatgaa tttgttcaag cagcatataa
    12301 gggattaaaa gaagctggaa tagattcaga aataactcaa tactcattct gtacgaatgg
    12361 aagtcactat gcaggtgaag ctggaataaa aactatagga tttggtcctt ctaaggaaaa
    12421 tcttgctcac acaatagatg agtatataga gcaagaacag ttatttatag gaacagaagg
    12481 ttactatgga atattaaaat ctgtatacgg aaaataatat ttagttcaca ataaattatt
    12541 taaatatagt ctagaggtgc tgaatatagc acctttagaa aatacaattt taaataaagt
    12601 tttacaatac ttagaaaata ctttaaagct taaaagttag gaggtatata tgggaacaat
    12661 actaagaggt ggaactataa ttacctctga taagacttat ataagtgatt taaggataga
    12721 agatgaaaag atagttgaaa taggaaataa tttagaaata aatggtgata aggttattga
    12781 tgctacaggt aaaattgtaa ttcctggtgg aatagacaca catactcatt ttgatatgaa
    12841 tgcaggttct attacaactg cagataattt tgaaacagga acaagagcag ctatagctgg
    12901 aggaactact acaatactag attttgcaga agccaatgag ggggaaaacc tactgcaagg
    12961 tgtagaagca tatcataaaa aagcaagtgg aaattgttat tgtgattatg gttttcatat
    13021 gacaattaca tgtttaaata aagatacatt taatcatatg gaaaaactta tttcggatgg
    13081 gatagtatct tttaagatgt atatggcata tgatggcatg aaagtagatg atggaacaat
    13141 atacagggtt ttaaagaaag caagggattt aggttgtata gttggatttc attgtgaaaa
    13201 tggggattta ctagatgtat tgatagaaga aaatatacaa aatggtaatt tagagccaaa
    13261 atatcatcca cttacaagac ctaacatagt tgagaaagag tctgtttcaa gacttgctga
    13321 tataactaaa ttatctaatt caaaatccta tgtagtccac ttaagttgta gggagtcact
    13381 tgaaactgta aaaatggcta gagaaaaaaa tatagatatg atagtagaaa catgcccaca
    13441 gtatctatta ttagaagaca atttatataa taaggataaa tttgagggtg ctaagtatgt
    13501 aatgtctcct cctttaagaa aaaaagaaga cataaattac ctttgggaag gattgtctag
    13561 tggagatatt caaacagttg gcacagacca ctgttcattt aattttaagg ggcaaaaaga
    13621 cttgggaatt gatgatttta gtaagatacc aaatggagca cctggtgttg aacataggct
    13681 agccctttta tatacatatg gggtcttaga aaatagaata agtgtaaata agtttgtgga
    13741 agttacttct acgaatgctg caaaaatatt tggaatgtat cctaaaaaag gtgagatagc
    13801 tgtaggaagt gatgcagata tagtcatttt aaatatcaat aaagaagaaa caattagtta
    13861 taaaactcaa aaacaaaatg tagattatac tccatatgaa ggatttaagg ttaaatgtaa
    13921 agttgaagat gtatttttga gaggaaatca tgtagtacaa agttgtaatg ttaaagaaca
    13981 tccaacaggt caatatatta aaagaaaaat tactaaataa tgcgggggga aataagaatg
    14041 atggatatac ttattaagaa tgccataata gtaactgtga ataaagagag agaagttatt
    14101 tttgatgggg cattagtagt aaaagataac aagattgctg atattggaaa ttctaaagag
    14161 atagaaagta aatatactga tgttaaaaaa attatagatg ctaaaggtaa agttttattc
    14221 ccaggtttta taaatacaca taatcattta ttccaaactt tattaaaagg attgggagat
    14281 gatatggtac ttaaagactg gttagaaact atgacatttc cagcagctaa ctatttagaa
    14341 ccaaaagata cttatgatgc tgcaatgctt ggatgtattg aaggacttag aagtggtata
    14401 acaacaatgg ttgactacat gtatcctcat agtaagccag gtctttgtga tggaataata
    14461 gatgcttata aagaattagg aataagagga atacttggaa gaggatgtat gaatacagga
    14521 gctcaatttg gagttcatcc tggaataatg caagatgtag aaacggttga aaaagatgta
    14581 agaagattgt ttgaaaaaca ccataataca gaaaatggaa gaatcaaaat aggagtagct
    14641 cctgcagcaa tatggtcaaa ttctcaagaa atgcttgaaa tgctatggag agtggtaaaa
    14701 gaatatgatg atgctttatt tacagtacat atatcagaga ctccttttga tagagaagca
    14761 gcaaaagaat tgcatgggca atatgacata gatgttttag aaaaattagg aatacttgga
    14821 ccaaatgtgc ttatggtaca ttgtgtgtat ctaactgaaa aagatatgga acttactaaa
    14881 aaatacgata tgaaagtgtc tcataataca gcaagtaata tgtacttatc ttcaggtgtt
    14941 gcaccagtgc cagaaatgct taaaaaagga ataacagtta gtttaggagt agatggagcc
    15001 gctagtaata actctcaaga tatgcttgaa cttatgaaat taacagcact tcaacataaa
    15061 gttaataagt gtgacccatt agcaatgtcg gcagaaaaag ttcttgagtt ggcaactata
    15121 gatggagcaa gagctattgg aatggaagat gagataggtt cattggagat aggtaaaaaa
    15181 gcagacttac taatatttaa tccaatgctt tcaccaaaag cgatacctat gcataatccg
    15241 gtatctacat tagtatattc ttctagtatg aaaaatatag agagtgttat agtagatgga
    15301 aatataataa tggaagattc aaaaatattg acagctaatg aagagaaagc attaaaagat
    15361 gctcaagata cagctgagag actttgtgta agaggaacta taaaaaatag aatggaaggt
    15421 cataaatgga atagccttta ttaataaatg taatttattc atagaaaagt atagtaaaac
    15481 tttagcttaa aaatatgagt tttgaggtga tttatttgat tatcaaatgt accataaata
    15541 ataaagaaaa agaattaagt ataagaccag atgatttttt agcagataca ttaagagaaa
    15601 atggatatgt aagtgttaaa aaagggtgtg atacaggctc atgtgggtta tgtacagtga
    15661 tggtaaatga caaggccgtg ctttcatgta attatcttac tgctagagta gatggtcagc
    15721 atattacaac acttgagggg gtcttggatg aagcaaagaa gtttggagat tttcttgcag
    15781 acgaaggggc tgaccagtgt ggattttgtg ctcctggatt tataatgatg gttttggcaa
    15841 tgaaaagaga gcttcaaaat ccaacagaag aagaagttat agattatgta aatggtaacc
    15901 tttgtagatg tacaggatat aaaggtcaat taagagcaat acataaatat ttaaacactt
    15961 agacttttaa gtgaaaatta agttgatatg gggagagagt atgataacta taaaggaata
    16021 tgtagttcca aaaagtttag atgaagctta tgaactgcta atatcaagaa aaaacaacat
    16081 aatacttgga ggatgtggat ttttaaaact aggtagtaaa aatattggct cagcaataga
    16141 tttaaaagac ttagctttag attatataaa tgaaactgat gatagcatat taattggagc
    16201 agacacaagt ttaagaactt tagaattaaa taaggttatt aaaaattact gtaatggggt
    16261 aatttcaaac gctgtttcta atatagtagg agttcaattt agaagtggag ccagagtagg
    16321 agctagcgta tttgctaagt atggattttc agatttaata ccttcattac tagtggtaga
    16381 tgcaaaggtt aagttatata aaaaaggggt tatgaactta gctgattttt tagaaagtga
    16441 gcttgaaaaa gatatattaa tagaagttat attacctaaa aaagatgcta taggtgtatt
    16501 tgattctata agaaaatgta caggtgattt tgcagtatta aatggagcaa tgttaaaaga
    16561 aggaagtatt tataaaattg cgataggcgc tagaccaaga agagcaaaaa ttgcctataa
    16621 agcaagtgaa atattaagtt tagaaaatga tatagaaaaa gctggtgaag tatcaagtga
    16681 agaactttca tttggaagta atataagagg aagtaaagaa tacagaaaag atatggcaaa
    16741 agccttagta gtgagaatgt ataatagtat tggaggtgag tgtgatggta aataaagagg
    16801 taagaaaaat agatagtgaa gccattgtta ctggaaaacc aatatataca gaagatttaa
    16861 tttttcataa agatgtttta acaattaagc ttcttagaag tccgcatgct tttgcgaaga
    16921 taaaaaacat agatacaaaa aatgcattaa aggtaaaagg tgtagtaaac atattcactt
    16981 acaaagatgt tccaaattat agatattcaa tggttggaga gtcatatcca gaagcatcac
    17041 ctcatgacca attaatactt gaagacgtag ttagatatgt aggagatgaa gttgctataa
    17101 tagccgctga agatgaaagg gctgctatta aagctatgaa acttataaaa gttgaatatg
    17161 aagtaatgat tcctatattg gatgcaagag aatcggaagg aaataaaatt ttaatccatg
    17221 aagaagatga tttgttttgt ccatttgatt ttggattgga tgctacaaaa aatattgtat
    17281 cgagagaaaa aatgggtaaa ggggatgtag aaaaagagtt taaagaaagt gatgtaatag
    17341 tagaacattc ttatatgact caatcacaag cccattgtat gatggaaact catagagctt
    17401 atacgtatat agatacgaat ggcagattag tagtaacttc tgcaaaccaa tcagcttatc
    17461 atatgagaag acaggtttct aaagcactgg gaatacctct ttcaaaagtt agagtaataa
    17521 aaccaagaat aggtggaggt tttggtggaa aaaacatagc tgtaacagag atatatgcat
    17581 catttgtaac ttggatgaca aaaagaccag caaaactaat ttatactaga gaagaaactt
    17641 ttgcaatgac taatactaga catcagatgt tttttgatat aaaaattggc gcagataaag
    17701 aaggaaacat aaaagctata gatatgaaag cattgaataa tacaggcgct tatggtgata
    17761 atggaccttc agtttgctct gaatcaggtc ataatgtact tccaacatat aataatgtac
    17821 ctgcaataaa atttgatggg agaactgtat atactaattt agttccagga ggagcattaa
    17881 gaggatatgg agcaacacaa ggtacatttg cacttgattg tgcaattgat gaattagcgc
    17941 ataaacttaa tatggaccca acagaaataa agttaaagaa tattataaaa aaacaaactg
    18001 aaggcggaat aatgaatttt ccaataagaa gttgtgcact tgatgaatgt ataattagag
    18061 gtaaaaaact tattggatgg gatgaaaagt accctgttag ggatattgga aacaataagg
    18121 tgagggctgt tggaatgtct gtgggaactc atggttctgg tatagccaac atagacatgg
    18181 caatagtaaa tatgaggatg gatgaagatg gaacttataa gttgttttct gggtcttcag
    18241 acttaggaac tggttctgac acaatacttg cacaaatagc tgcaaaagca ttgaatacat
    18301 ctattgatag aatttccgtt tatacaggag atacagatat gtgtccatat gatactggtg
    18361 catacgcttc ttgtactact tatgtaactg gaaatgctac aataaaatct gctgaaagtt
    18421 taaaacaaaa gatattaaaa gtagcacaga agaaactcga tttaccaata gatgatttaa
    18481 tactatatga agacagagtt tgttatagtg aagatgtaga gaagtttgtt ttgttaagtg
    18541 aattaggaaa agaatctgtt ggtggtggaa atcaagaagt tttatattca tctgaatctt
    18601 atggtataca agagagtgct aaaccattct tagcaggatt tgctgaaata gagttagata
    18661 aaacaacagg ggagtttaaa gtaataaatt atgcttgttc tacagattgt ggtacagtta
    18721 tgaatcctgc acttgctaga atacaagttg aaggtggtgt aactcaaggt atagggcttg
    18781 caatgtatga agaccctaga catggttctg atggaaagct tcaaacttct aatctattac
    18841 aatacaaagt tccaacaaaa aaagatatag gaaacataat tgttgatttt gtagataatt
    18901 atgagccaac aggtccatat ggagctaaat ctttaggaga aatagttatt catacacctg
    18961 caccagcaat agcaaatgca atatacaatg ccacaggagt tcgtataaga gaacttccta
    19021 taacttctga gaaagtttat atggccatga aaaaattaaa tcagggaggt aaataaatga
    19081 ttgctattaa aagtaaatac ttaatatctt ctgctgatga aatatataca aattctgctg
    19141 ttgtagtaga aaatgacatt ataaaagata tattgccaaa tgaagaagtt gaaataaaat
    19201 ataaaaatat tgaagaaata atagataaat cagatgctat aataatgcca ggattcgtca
    19261 atggtcatat gcatcaatat ggagttcttt ctaggggaat accggcaaat gtacatttta
    19321 ctgactttga aggtttttta aatgactatt ggtggccatt tatagaaaat agaattggat
    19381 tgaaagaagt gaaggcaaca actaaagcat cagcaataga acttatagaa tctggtgtgg
    19441 tagctttttg tgatacccta gaagctccaa atacagaaga aggaacttta attgagcaag
    19501 gaaaaatact agaagaaata ggcatgaaag cgattttatc cttagaaagt tgtgaaagaa
    19561 taagctttga aaatggactt agatgtttag atgaaaattc taatttaata aagtggagta
    19621 gagaaaatag taaattaata aatggaataa tgtgtacaca tacaagcttc acatgttctg
    19681 atagatttat taagaaagct aaagaagatg caaaaaaatt aaatgcacca atgcaatttc
    19741 atttatgtga gagtatatat gagccaaact atgctgaaaa acattttggc aaaaaagcag
    19801 ttgactacta taatgattta gatatattgg atgaaactgt attagcatct cagtgtgtaa
    19861 aagtaaatga tgaagaaata gatatattaa aagaaaaagg tgtaaaagtg gttcatatgc
    19921 ctcttagcaa ctgtgaagta ggtggaggtt tttctccagt accaaaaatg attaaaaaag
    19981 gcataaaagt ggcactgggt actgatggat atataaatga tttttttgaa gttatgagag
    20041 gtgcattttt aatgcataaa tcagttgaag aagatgcatc agtaatgcca gcaaatttag
    20101 tatttagaat ggcaacagag catggtgctt atgtattagg acttcaaaat tctggtaaaa
    20161 tagtagttgg taataaggct gatataatag ttatggaaga tgaatttaaa actcctgtga
    20221 ctcttgataa tatatttgac cagatagtag ttcagggtaa aaaagaattt atatcaaatg
    20281 tatacataga tggtagacat attttaaaag aaaaacagtt agttgattta gataaaaaag
    20341 ctattgttaa agaaatgaaa gaagttgctt gtgaattttg gaaattttaa cgaatgtaaa
    20401 tatatatgaa aaggggaagc agataatgta taatttttta ggtaaagaat taaaatcacc
    20461 acttataata ggttcaggac cattaacata tagtgcagct ggatgcaaga tattaagtga
    20521 tgcaggagca ggggcagttg tgactaagac tataagaaaa gaaagagcta taaatccagc
    20581 accacatatg gttagaaata caactaatgc tcttttaaat aatgaaaaat ggacagattt
    20641 tgagccagag caatggatag attttgaaat accacaaatg aaaagagatg ggactgtctg
    20701 tatagcttca gtaggtcata caattgaaga aagtagcgaa ttagtagaga aagttgcaaa
    20761 tgcaggagct gactttattg aattagtatc ttatgactat agagatttga taccaatgct
    20821 taaagatgca aaggaaagag taaatatacc tgtaatagtt aaacttcctc ctatgataga
    20881 tgagataggc gattttgcta aaaaattaga agaagcagga gcagatgcaa taactgcttg
    20941 tgactctgta ggaccagcat ttagaataga catagaaaca gggcaacctt tattaggtgg
    21001 aaatggaata ggatatttaa gtggagaaac tattaagcca ataactttac agagaatata
    21061 tgaaataaaa aaacaagtta atataccaat aattggctta ggtggatgcg taagtggaga
    21121 tgatgcctta gaaatgatta tggcaggtgc tgactttgtt ggtatatgtt cagtagtaat
    21181 tttaaaaggc gcacaagtaa tatctaaaat acatgatgat ttaaaatcta atcttaatag
    21241 attaggatat aatactatag aaaatgcttg tggtatagta cataatcata tgggagatgt
    21301 taatgaaaga cttagctttg agtttactta tgatgaagaa aaatgtacta aatgtaagat
    21361 gtgcgagaga gtttgtgcat atcaagcgag aaaattgaat gataagatgg aattgaatga
    21421 agaagagtgt agatattgtg gactttgtat atcagtttgt aaaccaaaag cacttggaag
    21481 aaaaatttca tgttcagagc tgaatgtata gattatttta taaaaaacaa agttttaaat
    21541 aaaaataaga aaggctatct caaagagata agcctttttt gttgttgacc ttatttttgt
    21601 ttatttgtag ttattttaga tattaattag ttttgaagta ataaagtgaa tcaattttgt
    21661 ttaattaaaa ttttaataat tctgatatat atgttaacat tgtatagcat ttgtgtaaaa
    21721 tgttataata attaataggg atggtgatgc aagtgcaaga gaagatttta gagttattat
    21781 atactataaa tgaagatgta gttagcataa aaaatgatat gtcggaagta aaacaagaaa
    21841 taaatgtgtt aaaagaagat atgtcggaag taaaacaaga aatgactgta atgaaagaag
    21901 atatgtcgga agtaaaacag gagataaatg tattaaaagg agatatgtcg gaagtaaaac
    21961 aagaaatgac tgtaatgaaa gaagatatat cagaagtaaa acaagaaatg ac
//
LOCUS       DACTZW010000072        21942 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.072, whole genome shotgun sequence.
ACCESSION   DACTZW010000072 DACTZW010000000
VERSION     DACTZW010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21942)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21942)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21942
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.072"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            370..681
                     /gene="rpsJ"
                     /locus_tag="JAM15_13865"
     CDS             370..681
                     /gene="rpsJ"
                     /locus_tag="JAM15_13865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008908582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HAT6799342.1"
                     /translation="MAKNEKIRIRLKSYDHKLLDFSAGKIVETAKKAGSQVSGPVPLP
                     TEKQVVTILRAVHKYKDSREQFEIRTHKRLIDIANPTPKTVDSLMRLDLPAGVDIEIK
                     L"
     gene            773..1402
                     /gene="rplC"
                     /locus_tag="JAM15_13870"
     CDS             773..1402
                     /gene="rplC"
                     /locus_tag="JAM15_13870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HAT6799343.1"
                     /translation="MKGILGKKVGMTQIFTDKGVVIPVTAVEAGPMVVTQIKTVDKDG
                     YNAIQIGFEDAKEKALNKPKKGHLAAANVLKKHLKEFRVDSVEGYTVGQEIKADVFEA
                     GAKIDVTGISKGKGFQGPIKRHGQSRGPETHGSRYHRRPGSMGACSYPGRVFKNKKLA
                     GHMGSVKVTVQNLEVVKVDADKNLILVKGAIPGAKGSVVTIKEAIKVSK"
     gene            1432..2055
                     /gene="rplD"
                     /locus_tag="JAM15_13875"
     CDS             1432..2055
                     /gene="rplD"
                     /locus_tag="JAM15_13875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HAT6799344.1"
                     /translation="MPKLNVLNVSGQNVGEIELSDSIFGVEVNGHVLYEVVKNQLANK
                     RQGTQSAKTRAEVRGGGRKPWKQKGTGRARQGSTRSVQWVGGGVAFAPKPRSYKYTLP
                     KKVRRLAMKSALSSKVQNSEVIVLDALNMDAPKTKEFAQILNNINAAKKALVVIADKN
                     DNVIKSARNIEGVQTALVNTMNVYDILKYDSFIITTDAVKKVEEVYA"
     gene            2055..2345
                     /gene="rplW"
                     /locus_tag="JAM15_13880"
     CDS             2055..2345
                     /gene="rplW"
                     /locus_tag="JAM15_13880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007791436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HAT6799345.1"
                     /translation="MTNPHDVIIRPVVTEHSMAEMGEKKYTFVVAKDANKTEIKKAVE
                     KVFGVSVDKVNTLNYDGKVKRMGRTQGRTSSFKKAVVKLTADSKEIEFFQGM"
     gene            2375..3205
                     /gene="rplB"
                     /locus_tag="JAM15_13885"
     CDS             2375..3205
                     /gene="rplB"
                     /locus_tag="JAM15_13885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HAT6799346.1"
                     /translation="MAIKKFRPTSPALRQMTVLVSDEITCNQPEKSLLVNLKKNAGRN
                     VHGRITVRHRGGGQKRKYRIIDFKRDKDGIPAKVATIEYDPNRTANIALLNYADGEKR
                     YILAPVGINVGDTILSGLGADIKPGNCLALKDMPVGTIIHNIELKPGKGAQLVRSAGV
                     SAQLMAKEGKNALLRLPSGEMRLVSINCKATIGQVGNIEHGNVVIGKAGRKRHMGIRP
                     TVRGSVMNPNDHPHGGGEGRSPIGRPSPVTPWGKPALGYKTRKKNKASNKLIVSRRTK
                     "
     gene            3240..3521
                     /gene="rpsS"
                     /locus_tag="JAM15_13890"
     CDS             3240..3521
                     /gene="rpsS"
                     /locus_tag="JAM15_13890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HAT6799347.1"
                     /translation="MSRSTKKGPFVHARLLKKIEAMNASGNKEVIKTWSRSSTVFPQM
                     VENTIAVHDGRKHVPVYITEDMVGHKLGEFVPTRTFKGHKDDEKSNKRK"
     gene            3553..3888
                     /gene="rplV"
                     /locus_tag="JAM15_13895"
     CDS             3553..3888
                     /gene="rplV"
                     /locus_tag="JAM15_13895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019595385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HAT6799348.1"
                     /translation="MEAKATAKYVRVSPRKAGQICDLVRGKNVDEALAILKFTPRGAA
                     SIIAKVVKSAKANAENNHEMDTEKLYIASIVANQGPTMKRFMPRAMGRATTIRKRTSH
                     IEVVVKEKK"
     gene            3911..4726
                     /gene="rpsC"
                     /locus_tag="JAM15_13900"
     CDS             3911..4726
                     /gene="rpsC"
                     /locus_tag="JAM15_13900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HAT6799349.1"
                     /translation="MGQKVNPHGLRVGVIKDWDSRWFATDKKEFGNLLLEDHNIRKFL
                     KKRLYSAGVAKIEIERSANKIKMDLHVAKPGVVIGRAGAGIEALKAELEKMTKKTIIV
                     NIVEVRSTDKNAQLVAENIALAIERRVAFRRAMKQAIQRAMKSGAKGIKVSASGRLGG
                     AEMARTEGYSEGNVPLQTLRADIDYGFAEADTTYGKIGIKVWICNGEVLPTRDGVNPR
                     EESRKSDRRDNKRDNRRNDRRGNDRRGNDNRGNYRGQRPQGGSRPQRTENKGN"
     gene            4762..5193
                     /gene="rplP"
                     /locus_tag="JAM15_13905"
     CDS             4762..5193
                     /gene="rplP"
                     /locus_tag="JAM15_13905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007791551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HAT6799350.1"
                     /translation="MLMPKRVKRRRVHRGSMAGQAHKGNKVTYGEFGLVALEASWITS
                     NQIEAARIAMTRYIKRGGKVWIKIFPHKPVTRKPAETRMGAGKGSPEYWVAVVKPGRV
                     MFELAGVSEDKAREAMRLAAHKLPIKCKFVKKEDLEVKGGE"
     gene            5195..5398
                     /gene="rpmC"
                     /locus_tag="JAM15_13910"
     CDS             5195..5398
                     /gene="rpmC"
                     /locus_tag="JAM15_13910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HAT6799351.1"
                     /translation="MKAKELRDLTSEELMNKLNDFKSELFSLRFQLATGQLENTARIK
                     FVKKDIAKVKTVLAERKLYETRA"
     gene            5422..5676
                     /gene="rpsQ"
                     /locus_tag="JAM15_13915"
     CDS             5422..5676
                     /gene="rpsQ"
                     /locus_tag="JAM15_13915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HAT6799352.1"
                     /translation="MERGRRKVRIGRVVSDKMDKTIVVAVEEFVRHPLYNKRVKRTKK
                     FKAHDEKNICNIGDRVKIMETRPLSKDKRFRLVEVVEKVK"
     gene            5702..6070
                     /gene="rplN"
                     /locus_tag="JAM15_13920"
     CDS             5702..6070
                     /gene="rplN"
                     /locus_tag="JAM15_13920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002598892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HAT6799353.1"
                     /translation="MIQQESRLRVADNSGAKELLCIRVLGGSKRRYGNIGDVIVATVK
                     SATPGGVVKKGKVVKAVIVRSKQGVRRNDGSYISFDENAAVIIKDDKTPVGTRIFGPV
                     ARELRDNEFMKIVSLAPEVL"
     gene            6094..6399
                     /gene="rplX"
                     /locus_tag="JAM15_13925"
     CDS             6094..6399
                     /gene="rplX"
                     /locus_tag="JAM15_13925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HAT6799354.1"
                     /translation="MRVKKGDTVVVIAGKDKGKKGSVLKVYPKTSKVLVEGVNVITKH
                     QKPSAMNQQGGIINKEAPIHISNVMPFDPETGKGVRVRYEVKDGNKVRVSAKSGKEL"
     gene            6429..6971
                     /gene="rplE"
                     /locus_tag="JAM15_13930"
     CDS             6429..6971
                     /gene="rplE"
                     /locus_tag="JAM15_13930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HAT6799355.1"
                     /translation="MASRLQEKYMKEVAPALMEKFGYKNVMEIPKLNKIVINMGIGDA
                     RENPKGLEKGVEELEMISGQKPVITKARKSVANFKLREGMPIGTKVTLRADKMFYFMD
                     KLVSVSLPRVRDFRGVNPNAFDGRGNYALGVKEQLIFPEIEYDKIDKVRGMDIIFVTT
                     AKTDEEARELLKLLGMPFSK"
     gene            6989..7174
                     /locus_tag="JAM15_13935"
     CDS             6989..7174
                     /locus_tag="JAM15_13935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003022786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HAT6799356.1"
                     /translation="MARKAMVVKQQRKQKYATREYTRCTICGRPHSVLKKFGICRICF
                     RELAYKGQIPGVRKASW"
     gene            7207..7605
                     /gene="rpsH"
                     /locus_tag="JAM15_13940"
     CDS             7207..7605
                     /gene="rpsH"
                     /locus_tag="JAM15_13940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HAT6799357.1"
                     /translation="MTMTDPIADMLTRIRNANVVKHETVDVPASNMKKELARILLEEG
                     FIRGYDVIEDGKQGIIRIQLKYGQEGERVITGLKKISKPGMRVYAANHEIPKVLNGLG
                     ISVISTSKGILTDKQARKENVGGEVICYVW"
     gene            7636..8178
                     /gene="rplF"
                     /locus_tag="JAM15_13945"
     CDS             7636..8178
                     /gene="rplF"
                     /locus_tag="JAM15_13945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HAT6799358.1"
                     /translation="MSRIGVKPIIIPAGVEVTIAEGNLVTVKGPKGTLTKQLSAELNI
                     KKEENTIMVERPTDNKKHRSLHGLTRTLLDNMVVGVNTGFEKKLELKGVGYRAQKQGK
                     KLVMNLGFSHPVEMEDPEGITVEAPNQTELIVKGIDKQLVGNYAAKIRAWRKPEPYKG
                     KGIKYVDEVIRRKEGKTGKK"
     gene            8214..8582
                     /gene="rplR"
                     /locus_tag="JAM15_13950"
     CDS             8214..8582
                     /gene="rplR"
                     /locus_tag="JAM15_13950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HAT6799359.1"
                     /translation="MLKKADKNANRLQRHKRVRRKISGTSQRPRLCVFRSANNIYAQI
                     IDDTKRVTLVAASSLEAEVKSAVNHTGNKEAAKKVGELVAKKAVEKGITEVVFDRGGY
                     LYHGRIQELAEGAREAGLKF"
     gene            8603..9112
                     /gene="rpsE"
                     /locus_tag="JAM15_13955"
     CDS             8603..9112
                     /gene="rpsE"
                     /locus_tag="JAM15_13955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009524366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HAT6799360.1"
                     /translation="MLRRKPIDAGQLDLQEKVVEVRRVTKVVKGGRNFRFAALVVVGD
                     ENGHVGIGAGKAMEVPDAIKKAVEDAKKNLIVVPIVGTTIPHEVRGHFGAGNILIMPA
                     VEGTGVIAGGPARAVLELAGLKDVRAKSLGSNNPRNMVNATIEGLNSLKTVEDIAKLR
                     GKKVEELLG"
     gene            9127..9312
                     /gene="rpmD"
                     /locus_tag="JAM15_13960"
     CDS             9127..9312
                     /gene="rpmD"
                     /locus_tag="JAM15_13960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HAT6799361.1"
                     /translation="MAKLQIKLVRSVIGTTPNQKKNVEALGLRKREQVVVKEDNAQTR
                     GMINKVSHLLEVTEIAE"
     gene            9345..9788
                     /gene="rplO"
                     /locus_tag="JAM15_13965"
     CDS             9345..9788
                     /gene="rplO"
                     /locus_tag="JAM15_13965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HAT6799362.1"
                     /translation="MKLHELKPAEGAVRAKRRLGRGTATGQGKTAGRGQKGQWSRSGG
                     GVRVGFEGGQMPLARRLPKRGFNNIFKKVYTEVNVEVLNRFENGTEITAELLKSTKTI
                     SKIGKDGIKILGEGNLEKALTVKAAKFTASAQEKIEKAGGKAELV"
     gene            9832..11100
                     /gene="secY"
                     /locus_tag="JAM15_13970"
     CDS             9832..11100
                     /gene="secY"
                     /locus_tag="JAM15_13970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002844191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HAT6799363.1"
                     /translation="MLSKLKQAWKIKAVRKKVMYTLMMIVIFRIGTTIPVPGIDTSII
                     QKMVGGNSLLSLYNMFTGGAFSNFSLFALGISPYITASIIIQLLTVGFESLAELQKSG
                     EEGKKKINKYTKYTALALAVVQALGITLGIVRSALISNSVFFITTVVITLVSASMLVM
                     WIGDKITEKGIGNGSSVIIFAGIISRIPTDVIKISQQVKSGEVAPWVIVILAVVILLT
                     VTGVTFIQEATRKIPVQYAKRVVGRKMYGGQSSHIPMKVNQSGVMPIIFASSLLAFPQ
                     TIAMFMGPNAQAFVQKYLSMATEQGFWTYRSIEILLIIFFSYFYTTVSFNTEDISKNM
                     KNNGGFIPGIRPGEPTMDYLNRILTRLTLAGATFLAIIAMVPALTTHYMKVNMSLAGT
                     SLLIVVGVALELKRQLESNLVMRSYQGFLK"
     gene            11117..11767
                     /locus_tag="JAM15_13975"
     CDS             11117..11767
                     /locus_tag="JAM15_13975"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HAT6799364.1"
                     /translation="MRIILLGPPGAGKGTQAAGIVEKYNIPHISTGDIFRKNIKEGTE
                     LGKKAKEYMDQGLLVPDELTVGLVTDRISQEDCKNGFMLDGFPRNVAQGEHLDIFLKN
                     AGISLDKVVNIEVDKSILVSRAVGRRICKSCGATYHVEFNPPKVEGVCDVCQGELYQR
                     ADDNEETVSKRIQVYLDETKPLVDYYSKQGIIADIKGDQAIDKVFEDIVAALGSGK"
     gene            11768..12514
                     /gene="map"
                     /locus_tag="JAM15_13980"
     CDS             11768..12514
                     /gene="map"
                     /locus_tag="JAM15_13980"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005367749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HAT6799365.1"
                     /translation="MIILKSKKEIELLREAGKIVADTHEVLRKAISPGISTLELDKIA
                     EENIRKYNAEPSFKGYGGFPGSICTSINREVVHGIPGETILQEGDIVSLDIGAYYKGY
                     HGDSAKTHGVGMISEEDRKLIEVTRESFYEGIKFAKLGYRLSDISHAVQTHVEKHGFS
                     VVRDLVGHGVGANLHEDPQVPNYGLPGKGPRLREGMVIAIEPMVNAGRYHVKTLSDGW
                     TTVTIDGKKSAHYEHTIAITEHEPLILTKL"
     gene            12536..12805
                     /locus_tag="JAM15_13985"
     CDS             12536..12805
                     /locus_tag="JAM15_13985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KOW domain-containing protein"
                     /protein_id="HAT6799366.1"
                     /translation="MLSDNLSIGQVVKVSLGRDKGNLFFVVKIINNEYVLIADGKKRK
                     LDKPKLKKVKHLKKYNFINDEVRKRVVSGQEITDSFLRAELTKLN"
     gene            12843..13061
                     /gene="infA"
                     /locus_tag="JAM15_13990"
     CDS             12843..13061
                     /gene="infA"
                     /locus_tag="JAM15_13990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HAT6799367.1"
                     /translation="MAKKDVIELEGTVSEALPNAMFKVKLENGHEILCHISGKLRMNF
                     IRILEGDKVNVELSPYDLTRGRITWRKK"
     gene            13097..13210
                     /gene="rpmJ"
                     /locus_tag="JAM15_13995"
     CDS             13097..13210
                     /gene="rpmJ"
                     /locus_tag="JAM15_13995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HAT6799368.1"
                     /translation="MKVRPSVKPICEKCKVIKRKGKVMVICENPKHKQKQG"
     gene            13363..13734
                     /gene="rpsM"
                     /locus_tag="JAM15_14000"
     CDS             13363..13734
                     /gene="rpsM"
                     /locus_tag="JAM15_14000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002844190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HAT6799369.1"
                     /translation="MARIAGVDLPREKRAEIGLTYIYGIGKATANEILAKAEINPDTR
                     IKDLSEDQVNELRKVIDDDFLVEGDLRREIALNIKRLRDIKCYRGIRHAKGLPLRGQR
                     TKTNARTRKGPRKTVSRKKKK"
     gene            13770..14168
                     /gene="rpsK"
                     /locus_tag="JAM15_14005"
     CDS             13770..14168
                     /gene="rpsK"
                     /locus_tag="JAM15_14005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007791581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HAT6799370.1"
                     /translation="MAKPKKKVTRIRRRERKNIERGHAHIQSTFNNTIITLTDVHGNA
                     ISWASSGQLGFKGSRKSTPFASQMAAETAAKAAMEHGLKSVEVFVKGPGSGREAAIRA
                     LQATGLEVTMIKDVTPIPHNGCRPPKRRRV"
     gene            14200..14823
                     /gene="rpsD"
                     /locus_tag="JAM15_14010"
     CDS             14200..14823
                     /gene="rpsD"
                     /locus_tag="JAM15_14010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HAT6799371.1"
                     /translation="MARYTGASCRQCRREGMKLFLKGDRCYTDKCAIVKRNYAPGQHG
                     QGRKKVSNYGLQLREKQKVKRIYGVLETQFRNLYERAENMPGKAGENLLSLLERRLDN
                     VVYRMGLASSRKEARQLVTHGHFTLNGNKVDIPSLIVKVGDVIEVKEKSRSSAKFKNL
                     VEVNSRIAPKWLEANVEGMTAKVVGVPTREDIDLEIAEHLIIELYSK"
     gene            14901..15848
                     /locus_tag="JAM15_14015"
     CDS             14901..15848
                     /locus_tag="JAM15_14015"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HAT6799372.1"
                     /translation="MIEIEKPKVDIVELSEDYRYGKFVIEPLERGYGITIGNALRRIL
                     LSSLPGVAVNAIKIDGVLHEFSTIPGVKEDVTEIILTLKELSATIDGEGSRTLKIEAQ
                     GPCSITGADIICPPDVEILSKDLAIATLDDNAKLNMEIFVDKGRGYVSAEENKTENVP
                     IGVLPVDSIYTPVEKVSYHVENTRVGQKTDYDKLVLEVWTNGSINPQEGISLAAKVLV
                     EHLNLFIDLTEHVSSVEIMVEKEEDQKEKVLEMTIEELDLSVRSYNCLKRAGINTVEE
                     LANKSEDDMMKVRNLGKKSLEEVIQKLEELGLGLKPSEE"
     gene            15869..16210
                     /gene="rplQ"
                     /locus_tag="JAM15_14020"
     CDS             15869..16210
                     /gene="rplQ"
                     /locus_tag="JAM15_14020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007791394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HAT6799373.1"
                     /translation="MAKYRKLGRETAHRNLMLRNLVTCLLRSGRIETTVTRAKETRRM
                     AEKMITLAKRGDLHARRQVLAYVMDETVVNNLFTDLAPKYAERNGGYTRIIKIGPRKG
                     DAAEMAFIELV"
     gene            16330..17163
                     /locus_tag="JAM15_14025"
     CDS             16330..17163
                     /locus_tag="JAM15_14025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HAT6799374.1"
                     /translation="MDNIVKVNNISFEYITDEAKLKAIDNLSLDVKKGEFVAIIGHNG
                     SGKSTLSKNLNAILMPTEGNILIDDMDTKEEERLWDIRQTAGMVFQNPDNQIVATIVE
                     EDVAFGPENLGIEPKEIRRIVEESLKSVGMYDLRDRQPHLLSGGQKQRVAIAGIIAMR
                     PKCIIFDEATAMLDPSGRKEVMKTIKRLNKEENITVIHITHFMEEAVEADRVVVMEKG
                     KKILEGTPREVFSKIKMLKEIGLDVPCMTELSSLLIEEGINISSDILTVDEMVMELCQ
                     L"
     gene            17151..18017
                     /locus_tag="JAM15_14030"
     CDS             17151..18017
                     /locus_tag="JAM15_14030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HAT6799375.1"
                     /translation="MSIIVKNLTHIYNEGMPFASKALDDVSFEIKDRDFVGLIGHTGS
                     GKSTLIQHLNGLLKPSSGEIFINDFNITDKNLNLTEIRKRVGVVFQYPEYQLFEETID
                     KDIAFGPSNLGLEESEIHNRVKASMEAVGLDYEGFKDKSPFELSGGQKRRVAIAGVIA
                     MNPEVLILDEPTAGLDPGGRDEIFNLIKDLHEKKNMTIILSSHSMDDMAKLAKTLIVM
                     NHGSVEFMGTPREVFKSNASKLKDIGLDIPQVLELALKLREKGFDISEDILTLEEAKQ
                     EILKVVRGRGLC"
     gene            18011..18814
                     /locus_tag="JAM15_14035"
     CDS             18011..18814
                     /locus_tag="JAM15_14035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HAT6799376.1"
                     /translation="MLKDITIGQYYPTSSAIHKLDPRIKLVATIVFMVSIFVVNKFWP
                     YIVVLLCLLAMIKLANIPVKYIVKGVKPLKWIILFTFLINIFFLPGDEIWSFGFLAIT
                     KQGLRQAIFMAIRLIFLVVGTSLLTLTTSPIELTDGIERLLNPFKKIGLPVHELAMMM
                     TIALRFIPTLLDETDKIMKAQMSRGADFESKNLINRAKNLVPLLVPLFVSAFRRADEL
                     AMAMEARCYRGGHNRTKMRESVISRRDYMACVFQVVYLGAIIATRFIAI"
     gene            18846..19577
                     /gene="truA"
                     /locus_tag="JAM15_14040"
     CDS             18846..19577
                     /gene="truA"
                     /locus_tag="JAM15_14040"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HAT6799377.1"
                     /translation="MRNIKIKIQYNGKNYCGWQKQPDSLGIQGTIERAIYDITKEETS
                     LIGSGRTDSGVHAIGQIANFKINSGISIESIPMALNAKLPKDISVIEACEVNDDFHSR
                     YSAKGKTYKYLVYNSKFRNPILSEISYQVKYELDFDKMCSEAKSLLGTHDFKGFMSSG
                     SSVKDTVRTIYDIGISKKDDLITFEISGNGFLYNMVRIIVGTLVDMGRGRINEPFLDI
                     IQSKTRSRCGHTAPAQGLFLKKVHY"
     gene            19697..20128
                     /gene="rplM"
                     /locus_tag="JAM15_14045"
     CDS             19697..20128
                     /gene="rplM"
                     /locus_tag="JAM15_14045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HAT6799378.1"
                     /translation="MKSYIAKPADVQRKWYLVDAEGKTLGRLATEIATVLRGKHKPTF
                     TPHVDGGDFVVVVNAEKIVLSGKKLDQKYYRYHTGYVGGLKEISYRDMMDKKPEEVIS
                     HAVSGMLPKNKLRSRMMTRLRVFAGAEHTHAAQNPEVLNFK"
     gene            20157..20549
                     /gene="rpsI"
                     /locus_tag="JAM15_14050"
     CDS             20157..20549
                     /gene="rpsI"
                     /locus_tag="JAM15_14050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HAT6799379.1"
                     /translation="MANVQYYGTGRRKSSVARVRLVAGEGNILVNGRALENYFNYETL
                     IRDVKQPLVLTGNENKYDVIVKVEGGGFTGQAGAIRHGISRALLKADLDLRPALKKEG
                     FLTRDARMKERKKYGLKAARRAPQFSKR"
     gene            21008..21760
                     /gene="cwlD"
                     /locus_tag="JAM15_14055"
     CDS             21008..21760
                     /gene="cwlD"
                     /locus_tag="JAM15_14055"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase CwlD"
                     /protein_id="HAT6799380.1"
                     /translation="MEYYSVFISIHIQGDVVRKYIKHIIFSFAMICLVVVSIFEIKNI
                     SEDVIKYMPVTNKTIILDAGHGGIDPGALNKDKSTSEKDINLAITLKLRELIESSGGL
                     VILTREDDSSLYKEENNKTTRQKYNENLKNRKEIISNSNANMFVSIHLNAFEQSKYYG
                     AQTFYPKDKQDSKELSKCIQEELKRVVDKTNNREVKPRDDIYLLKENNIPSVLIECGF
                     LSNEKECKLLTDETYQEKIAWAIYIGIQKYLS"
BASE COUNT         8814 a         2567 c         4496 g         6065 t
ORIGIN      
        1 ctttactaaa ctaatggatt taatataaaa aaagaggggg gtaactcctc tcttttttgt
       61 tttttgttga caagtagcgc taaagcatat atactaaact agtgccttga gacagattaa
      121 caatcaagtt taaggttatg atgttgtaat agaaaataaa attgaaaaaa acagaaaaaa
      181 aacttgaaaa aatgtaacag atgatataaa atataatagt gtgcttgaga gattaagaaa
      241 ataataatta aatcctagtg aaatacgaac tgatatcgat ttaaaagtta caacacaccc
      301 ggagcagtgt atcggtattg gttgtacgca acttgaaaat taaacacgtg ataaaggagg
      361 gaaaacaaaa tggctaagaa tgaaaaaata agaataagat taaaatcata tgatcacaaa
      421 ttattagatt tttcagcagg taaaatagtt gaaactgcta aaaaggctgg atcacaagtt
      481 tcaggacctg tgcctctacc aacagaaaaa caagttgtaa ctatattaag agctgtacat
      541 aagtacaaag actctagaga acaatttgaa ataagaactc ataaaagact aatcgacata
      601 gctaatccaa cacctaagac agttgactca ttaatgagat tagacttacc agcaggtgta
      661 gatatagaaa taaaattata agaaccccta agatattatc ctatagatga ttatcttaga
      721 atgattactc taaaagatgt aatccgctgt aagaattata ggaggtgcta atatgaaagg
      781 aatattaggc aaaaaagttg gtatgactca aatattcact gataaaggtg tagttatacc
      841 tgtaacagct gttgaagcag ggcctatggt cgttactcaa ataaaaacag ttgataaaga
      901 tggatacaat gctatacaaa taggttttga agatgctaaa gaaaaagctt taaacaaacc
      961 taaaaaagga catttagctg ctgctaatgt tttaaagaaa catttaaaag aatttagagt
     1021 agattctgta gaaggataca cagtaggaca agaaataaaa gctgatgtat ttgaagcagg
     1081 tgcaaaaata gatgttactg gaataagtaa aggtaaggga ttccaaggtc caataaaaag
     1141 acatggacaa agtagaggtc ctgaaactca cggttctaga taccacagaa gaccaggttc
     1201 aatgggagct tgttcttacc caggtagagt atttaaaaac aaaaaattag ctggacatat
     1261 gggaagcgta aaggtaacag ttcaaaactt agaggttgtt aaagtagatg ctgacaagaa
     1321 ccttatatta gttaaaggag ctataccagg agctaaaggt tcagtagtaa ctataaaaga
     1381 agctataaag gtttctaaat aatgactaac ctagagaaag gaggaataac aatgccaaaa
     1441 ttaaatgtac taaatgttag tggacaaaac gttggagaaa tagaattatc agattctata
     1501 tttggcgtag aagttaatgg acatgtttta tacgaagttg taaaaaatca attagcaaat
     1561 aagagacaag gaactcaatc tgctaaaact agagcagaag ttagaggtgg cggaagaaaa
     1621 ccttggaaac aaaaaggaac aggtagagca agacaaggtt ctacaagatc tgtacaatgg
     1681 gtaggaggag gagttgcttt tgcacctaaa ccaagaagct acaaatatac attacctaag
     1741 aaggtaagaa gattagctat gaagagtgct ttatcttcaa aagttcaaaa tagtgaagtt
     1801 atagtattag atgcattaaa catggatgct cctaagacta aagaatttgc tcaaatatta
     1861 aacaatataa atgctgctaa aaaagcttta gtagttatag ctgacaaaaa cgataacgta
     1921 ataaaatcag ctagaaatat agaaggtgtt caaactgcat tagttaatac tatgaatgta
     1981 tatgatatat taaaatacga ttcatttata ataactacag atgctgttaa aaaagtggag
     2041 gaggtgtacg cataatgact aatccacatg atgtaataat aagaccagtt gtaactgagc
     2101 acagtatggc tgaaatgggt gaaaaaaaat acacttttgt tgtggctaaa gatgcgaaca
     2161 aaactgaaat aaaaaaagca gtagaaaaag tattcggagt tagtgttgat aaagtaaata
     2221 ctttaaacta cgatggaaaa gttaaaagaa tgggtagaac tcaaggaaga acatcaagct
     2281 ttaagaaagc agtagttaaa ttaactgctg atagtaaaga aatagaattc ttccaaggaa
     2341 tgtagtatta taacaaacga aggagggaaa acagatggct ataaaaaagt ttagaccaac
     2401 ttctcctgcc ttaagacaaa tgacagtttt agtttctgat gaaataacat gtaatcaacc
     2461 agaaaaatct cttttagtta acttaaagaa aaatgctggt agaaacgtac atggtagaat
     2521 aactgttcgt catagaggtg gaggacaaaa aagaaaatat agaataatag attttaaaag
     2581 agataaagat ggtatacctg ctaaggttgc tactatagaa tatgatccaa acagaactgc
     2641 aaatatcgca ttattaaact atgctgatgg agaaaaaaga tatatattag ctccagttgg
     2701 aattaacgtt ggagatacta tattatcagg attaggtgct gatataaaac caggaaactg
     2761 tttagcatta aaagatatgc cagttggtac tatcattcat aatatagaat taaagccagg
     2821 aaaaggagct caattagtta gatctgctgg agtttctgca caattaatgg ctaaagaagg
     2881 aaaaaatgct ttattaagat taccatcagg tgagatgaga ttagtaagca taaactgtaa
     2941 agctactata ggtcaagttg gaaatataga gcatggtaac gtagttatcg gtaaagcagg
     3001 tagaaaaaga catatgggaa taagacctac tgtaagaggt tctgtaatga accctaatga
     3061 ccatccacac ggtggagggg aaggtagatc tccaataggt agaccatctc ctgttactcc
     3121 atggggtaaa ccagctcttg gatacaaaac tagaaagaaa aataaagctt caaataaact
     3181 aatagtatca agaagaacta agtagtaaat ttatttttgc tcggaaagga ggaatataaa
     3241 tgtcaagatc aactaaaaaa gggccttttg tccatgcaag acttttaaag aagatagaag
     3301 ctatgaatgc tagtggaaat aaagaagtta taaaaacttg gtcaagatct tcaactgtat
     3361 ttccacaaat ggtagaaaac actatagctg ttcatgatgg aagaaaacat gttccagtat
     3421 atataacaga agatatggtt ggacataaat taggtgagtt cgttcctact agaactttca
     3481 aaggacataa ggatgacgaa aaatctaata agagaaaata attaaattat gactaagaaa
     3541 ggaggaataa caatggaagc aaaagctact gctaaatacg tacgtgtatc accaagaaaa
     3601 gcaggccaaa tatgtgacct tgttagagga aagaatgttg atgaagcatt agcaatatta
     3661 aagtttactc caagaggagc agcttcaata atagctaagg ttgtaaaatc agctaaagct
     3721 aacgcagaaa acaatcacga aatggatact gaaaaattat atatagcatc aatagttgct
     3781 aatcaaggac caacaatgaa gagattcatg cctagagcta tgggtcgtgc aactacaata
     3841 agaaaaagaa cttctcatat agaggttgtt gttaaagaaa aaaaataatt aatagatagg
     3901 agggaaagta atgggtcaaa aggttaatcc acacggctta agggtcggtg ttataaaaga
     3961 ttgggactca agatggttcg ctactgataa aaaagagttc ggaaacttat tattagaaga
     4021 ccataatata cgtaaattct taaagaaaag attatactca gctggagttg ctaagataga
     4081 aatagaaaga tcagctaaca aaataaaaat ggacttacac gttgctaagc ctggtgtagt
     4141 tataggaaga gctggtgcag gaatcgaagc attaaaagct gaattagaaa aaatgacaaa
     4201 gaaaactata atagttaata tagtagaagt aagaagtaca gataaaaatg ctcaattagt
     4261 agctgagaat atagctttag ctatagagag aagggttgct ttcagaagag caatgaaaca
     4321 agctatacaa agagcaatga aatctggtgc taaagggata aaagtttctg cttcaggaag
     4381 attaggtgga gctgaaatgg ctagaactga aggttatagt gaaggaaatg tgccactaca
     4441 aactttaaga gcagatatag attatggttt cgctgaagct gatacaactt atggaaaaat
     4501 cggtataaaa gtttggatat gtaatggtga agttttacca actagagacg gtgtaaatcc
     4561 aagagaagaa agcagaaaga gcgatagaag agacaacaag agagataata gaagaaacga
     4621 tagaagagga aatgacagaa gaggaaatga taacagagga aactacagag gacaaagacc
     4681 tcaaggtgga tcaagacctc aaagaactga aaacaaagga aattaataat agttaggttc
     4741 aaggaaggag gaaaaatact catgttaatg ccaaaaagag taaagcgtcg tagagttcat
     4801 agaggaagca tggctgggca agctcataag ggtaataaag ttacttatgg tgagtttgga
     4861 ttagtagcat tagaagcttc ttggataact tctaatcaaa tagaagctgc cagaatcgcg
     4921 atgactagat atataaaaag agggggaaag gtttggataa aaatattccc tcataaacca
     4981 gtaacaagaa aaccagcaga gactcgtatg ggtgcaggga aaggttctcc agaatattgg
     5041 gtagctgtag ttaagccagg aagagttatg tttgaattag caggtgtttc tgaagataaa
     5101 gcaagagaag ctatgagact tgctgcacat aaattaccaa tcaaatgtaa atttgttaaa
     5161 aaagaagatt tagaagtaaa gggtggtgaa taggatgaaa gctaaagaat taagagattt
     5221 aacaagcgaa gagctaatga acaaattaaa cgacttcaaa agtgaattat ttagcttaag
     5281 attccaatta gctactggtc aattagaaaa tacagctaga ataaagtttg ttaagaagga
     5341 tatagcaaaa gttaaaactg ttcttgctga aagaaagtta tacgaaacta gagcttaatt
     5401 tggaaaggag gctttttaaa catggaaaga ggaagaagaa aagttagaat aggccgtgtt
     5461 gttagtgata agatggataa aacaatagta gtagctgttg aagaattcgt acgtcatcca
     5521 ctatataata aacgtgttaa gagaactaag aaattcaagg ctcatgatga aaagaatata
     5581 tgtaacatcg gagatagagt taaaataatg gaaactagac cattatctaa agataagaga
     5641 ttcagactag ttgaagttgt tgagaaagtt aagtagtttt tgaagaagga gggattacga
     5701 tatgatacaa caagaatcac gtctaagagt tgctgataac tcaggagcta aagaactttt
     5761 atgtatacgt gttctaggcg gaagtaaaag aagatatggt aacataggcg acgttatagt
     5821 tgctactgtt aaaagtgcaa cacctggtgg agttgtaaaa aaaggtaagg ttgttaaagc
     5881 tgttatagta agaagcaaac aaggcgtaag acgtaatgac ggaagctata tatcttttga
     5941 tgaaaatgct gctgttataa taaaggacga taaaactcca gtaggaactc gtatattcgg
     6001 gcctgttgct agagagttaa gagacaatga attcatgaaa atagtttctc ttgctccaga
     6061 agtactataa ttaaggaggt gcaataggac atgatgcgtg ttaaaaaagg tgacactgtt
     6121 gtagttatag caggtaaaga taaaggtaaa aaaggttcag ttttaaaggt atatcctaaa
     6181 actagcaaag tgttagttga aggtgtaaat gtaataacta aacatcaaaa accaagtgct
     6241 atgaaccaac aaggtggaat aataaataaa gaagccccaa tacacatatc taatgtaatg
     6301 ccatttgatc ctgaaacagg aaaaggcgtt agagtaagat atgaagtaaa agatgggaac
     6361 aaagtaagag tatcagcaaa gagcggaaaa gaattataat aaatattgct tgaaaggagg
     6421 gaccttaaat ggcttctaga ttacaagaaa aatacatgaa agaagttgct cctgctttaa
     6481 tggagaaatt tggatacaaa aacgtaatgg agatacctaa gttaaataaa atagttatta
     6541 acatgggtat aggtgacgct agagaaaatc caaaaggatt agaaaaaggc gttgaagaat
     6601 tagaaatgat atcaggacaa aagcctgtta taactaaagc tagaaaatct gttgctaact
     6661 tcaaattaag agaaggaatg ccaataggaa caaaagttac attaagagct gacaaaatgt
     6721 tctacttcat ggacaaatta gtttcagttt ctttaccaag agttagagac tttagaggag
     6781 ttaaccctaa tgcttttgat ggtagaggaa attatgcttt aggagttaaa gaacaattaa
     6841 tattccctga aatagaatat gataaaatag ataaagtaag aggaatggat ataatatttg
     6901 ttactacagc aaaaactgac gaagaagctc gtgaattatt aaaattatta ggaatgccat
     6961 tttctaagta agcaaaggag ggattcccgt ggctagaaaa gcgatggttg ttaagcaaca
     7021 aagaaagcaa aagtacgcta ctagagaata cactagatgt actatatgcg gaagaccgca
     7081 ttcagttttg aaaaaatttg gtatatgccg tatatgcttt agagaattag cttataaagg
     7141 tcaaatacct ggtgttagaa aagcaagctg gtagaagctt gattagaatg gaaggagggc
     7201 aacaaaatga caatgacaga tccaattgca gatatgctta ctcgtataag aaatgctaat
     7261 gttgttaagc atgaaactgt agatgttcca gcttctaata tgaagaaaga attagctaga
     7321 atcttattag aagaaggttt cataagaggt tatgatgtta tagaagatgg aaaacaaggt
     7381 atcataagaa tacaattaaa gtacggacaa gaaggcgaaa gagttataac aggtcttaag
     7441 aaaatatcta agcctggaat gagagtttac gctgctaacc atgagatacc aaaagtatta
     7501 aacggattag gaatatcagt tatatctact tcaaaaggaa tattaactga caagcaagct
     7561 agaaaagaaa atgttggtgg agaagtaatc tgctacgttt ggtaattaat atgaacaatg
     7621 taaggaggtg cgaccatgtc aagaataggt gttaagccaa taataatacc agcaggtgtt
     7681 gaagttacta tagctgaagg aaatttagtt acagtaaaag gtccaaaagg aactttaact
     7741 aaacaattaa gtgctgagtt aaacataaaa aaagaagaaa atacaataat ggttgaaaga
     7801 ccaactgata ataaaaaaca tagatcttta cacggactaa ctagaacttt attagataat
     7861 atggttgtag gtgtaaatac tggtttcgaa aagaaattag aattaaaagg tgttggatat
     7921 agagctcaaa aacaaggaaa gaaattagtt atgaacttag gtttctctca tccagttgag
     7981 atggaagatc cagaaggaat aactgttgaa gctccaaacc aaacagagtt aatagtaaaa
     8041 ggtatagaca agcaattagt agggaattat gctgctaaga taagagcttg gagaaagcca
     8101 gagccataca aaggtaaagg tataaaatac gttgatgaag taatcagacg taaagaagga
     8161 aaaactggta aaaaataata ccaaaactta aacgctagaa aggagtgagc taggtgttaa
     8221 aaaaggctga taaaaatgct aatagacttc aaagacataa gagagttcgt agaaaaataa
     8281 gcggtacttc tcaaagacca agattatgtg tatttagaag tgctaacaat atatatgctc
     8341 aaataataga tgacacaaaa agagtaactc tagttgctgc atcttcttta gaagcagaag
     8401 ttaagagtgc tgtcaatcat acaggaaaca aggaagcagc taagaaagtt ggagaattag
     8461 ttgctaaaaa agctgttgaa aaaggaatca ctgaagttgt atttgacaga ggtggatact
     8521 tatatcatgg aagaattcaa gaattagctg aaggtgctag agaagctggt cttaagttct
     8581 aatacgaagg agggaaaaat acatgctacg tcgtaagccg atagatgcag gacaacttga
     8641 cttacaagaa aaagttgttg aagtaagacg tgttactaag gttgtaaaag gtggtagaaa
     8701 tttcagattt gcagcattag tagttgttgg agatgaaaac ggacacgttg gtataggtgc
     8761 tgggaaagca atggaagtac cagacgctat aaaaaaagca gttgaagatg ctaagaaaaa
     8821 tctaatagta gtgccaatag ttgggactac aattcctcac gaagtacgcg gacactttgg
     8881 tgctggaaat atattaataa tgcctgctgt agaaggtaca ggagtaatag ctgggggacc
     8941 tgctagagcc gtacttgagc tagctggact aaaagacgtt agagctaaat ctttagggtc
     9001 taacaatcca agaaatatgg taaatgctac aatagaagga cttaattctc taaaaacagt
     9061 tgaagatata gctaaactta gaggtaaaaa agttgaagaa cttctagggt aaggaggtag
     9121 tgtaaaatgg ctaaattaca aataaagtta gttagaagtg ttataggaac tactcctaac
     9181 caaaaaaaga atgttgaagc gttaggatta agaaaaagag aacaagttgt tgtaaaagaa
     9241 gacaatgctc aaacaagagg tatgataaat aaagtaagtc acttattaga agtaactgaa
     9301 atagctgaat aatttttata aagtagtgca aggaggtgca atccatgaag ttacatgagt
     9361 taaaacctgc tgaaggtgca gtaagagcta agagaagatt aggtagaggt actgcaactg
     9421 gacaaggtaa aactgcagga cgtggacaaa aaggtcaatg gtctcgttct ggtggtggag
     9481 taagagtagg atttgaaggt ggacaaatgc cactagctag aagacttcct aagagaggtt
     9541 tcaataacat atttaagaaa gtttacacag aagttaatgt tgaagtttta aacagatttg
     9601 aaaatggaac agaaataact gcagaattat taaaatctac taaaactata agcaaaatag
     9661 gtaaagacgg aattaaaatc ttaggtgaag gtaatttaga gaaagcttta actgttaaag
     9721 ctgctaaatt tacagcttca gctcaagaaa aaatagaaaa agctggtgga aaagcagagt
     9781 tagtataata acctgctaat ctcctagcca gtacaggcgg ggtgaattag cgtgctgtca
     9841 aaattaaaac aagcttggaa gattaaagca gtaagaaaaa aagtaatgta tacacttatg
     9901 atgatcgtga tattcagaat aggtactact ataccagttc caggcataga cactagtatt
     9961 atacaaaaga tggtaggcgg caatagtcta ctttctctgt ataatatgtt tactggtgga
    10021 gcatttagta acttttcact atttgcttta ggtataagtc catatatcac tgcatcaatc
    10081 ataatacaac ttctaacagt aggttttgaa agtttagcag aacttcaaaa atctggtgaa
    10141 gaaggaaaga aaaaaatcaa taagtacact aaatatacag cactagctct agcagttgta
    10201 caagctttgg gaattacatt aggaattgta agaagtgctt taatatcaaa tagtgtgttt
    10261 tttatcacaa ctgttgtaat aacattagtt tcagcaagta tgttagtaat gtggattggg
    10321 gacaaaatta ctgaaaaagg aatcggtaat ggtagttcag taataatatt tgcaggtata
    10381 atatcaagaa tacctacaga tgttattaaa atatcgcaac aagttaaatc tggcgaagtt
    10441 gcaccttggg ttatagtgat tctagctgta gttatattac ttacagtaac aggagttaca
    10501 tttatacaag aagcaactag aaagatacct gtacaatatg ctaaaagagt tgttggaaga
    10561 aaaatgtatg gaggacaaag ttctcatata ccaatgaaag ttaaccagtc aggagttatg
    10621 cctataattt ttgctagttc acttttagct ttccctcaaa caatagctat gtttatgggt
    10681 ccaaatgctc aggcttttgt tcaaaaatac ttaagtatgg caacagaaca aggattttgg
    10741 acatatagat caattgagat tctacttata attttcttct catattttta tacaactgta
    10801 tcatttaata cagaagacat atctaaaaat atgaaaaata atggtggatt tataccaggt
    10861 ataagaccag gtgagcctac tatggattat ttaaatagaa ttttaactag attaacttta
    10921 gctggagcta ctttcttagc aataattgct atggtgccag ctcttacaac acattatatg
    10981 aaagtaaata tgagtctagc tgggacttca ttgctaatcg ttgttggagt tgctttggag
    11041 cttaagagac agttagagtc aaacttagtt atgagaagct atcaaggttt cttaaaataa
    11101 aatggagatg gataatatga gaataatatt acttggacct ccaggtgctg gtaaaggtac
    11161 tcaggcggca ggaatagtag aaaaatacaa tatacctcat atatcaacag gagatatatt
    11221 cagaaagaat ataaaagagg gaacagaact tggaaaaaaa gctaaagaat acatggacca
    11281 aggtttatta gtaccagatg agttaactgt aggtttagtt actgatagaa tatctcaaga
    11341 agattgtaaa aatggattta tgttagatgg atttccaaga aatgtagcac aaggagaaca
    11401 tttagatatc ttcttaaaaa atgctggtat atcactagat aaagttgtca atattgaagt
    11461 tgataagagt atattagtgt ctagagcagt tggtagaaga atatgtaagt cttgtggagc
    11521 tacttaccat gttgagttta atcctcctaa agtagaaggt gtatgtgatg tatgccaagg
    11581 agaattatat caaagagctg atgataatga agaaactgta tctaagagaa tacaagttta
    11641 tctagatgaa actaagcctt tagtagatta ttatagcaaa caaggtataa tagcagatat
    11701 aaaaggtgat caagcaatag ataaagtatt tgaagatatt gtcgcagcct taggaagtgg
    11761 aaaataaatg attatcttga aatcaaaaaa agaaatagaa cttttaagag aagcaggtaa
    11821 aatagttgct gacactcatg aagttttaag aaaagctatt tctccgggaa tatctacttt
    11881 agaattagat aaaatagctg aagagaatat aagaaaatac aatgcagaac cttcttttaa
    11941 aggatatgga ggttttccag gaagtatatg tacttctatc aatagagagg tagtacatgg
    12001 tattccagga gaaactatat tacaagaagg tgacattgta agtttggata taggagccta
    12061 ttataaagga tatcatggtg attctgcgaa aactcacgga gtaggcatga tatctgaaga
    12121 agataggaaa ttgatagaag taactagaga aagcttctat gaaggaataa aatttgctaa
    12181 attaggatat agactttcag atatctcaca cgcagtacaa acacacgttg agaaacatgg
    12241 tttctcggta gttagagatt tagtgggtca tggagttgga gcaaatcttc atgaagaccc
    12301 acaagtacct aattatggac tcccaggaaa aggaccaaga cttagagaag gaatggttat
    12361 tgctatagag ccaatggtta atgcaggtcg ttatcatgta aagactctat cagatgggtg
    12421 gacgactgtt acaatagatg gaaaaaaatc agctcattat gagcatacga tagcaattac
    12481 tgaacatgaa cctttgatat tgacaaagtt gtaatttaaa aagtaggtga aaaaagtgct
    12541 atcagataat ttaagtatag gtcaagttgt taaagtttca ttaggacgag ataaaggaaa
    12601 tttattcttt gtagtcaaaa taattaataa tgaatatgta ttaatagctg atggaaaaaa
    12661 gagaaaactt gacaaaccta agttaaagaa agtgaagcac ttaaaaaaat ataattttat
    12721 taatgatgaa gttagaaaaa gagtagtatc tggacaagag attacagatt cttttttaag
    12781 agctgaactt actaagttaa attagataat ttaacttatt gaaatggagg gctggttagt
    12841 taatggccaa aaaagatgtt atagaattag aaggtacagt ttcagaagct ttacctaatg
    12901 ctatgttcaa agttaaacta gaaaatggac atgagatatt atgccacatt tctggaaagc
    12961 taagaatgaa cttcataaga attcttgaag gtgacaaggt gaatgttgaa ctttctccat
    13021 atgaccttac aagaggaaga attacttggc gtaagaagta gactatatta atatttagtc
    13081 taaggaggga ttaataatga aggttagacc atcagtaaaa ccaatatgtg aaaaatgtaa
    13141 agtaataaaa agaaaaggaa aagtaatggt tatctgtgaa aatccaaagc ataagcaaaa
    13201 gcaaggataa gaaattatta ctagcatttt gttaaatttt atagtataat actatattgt
    13261 gatattaaca aaagaacgtt aaaatcgttg aacaatctgg cgtaggattg gcatatgatg
    13321 tgaagtttta aacactaaaa actatgtgta ggaggtgcga tcatggcaag aatagctggg
    13381 gtagatttac ctagagaaaa aagagcggag ataggcttaa cttatatata tggtataggt
    13441 aaagcaactg ctaacgaaat attagctaag gctgagataa atccagatac tagaataaaa
    13501 gatttatcag aagatcaagt taatgagtta agaaaagtta tagatgacga tttcttagtt
    13561 gaaggtgact taagaagaga aattgcttta aacataaaga gattaagaga tataaaatgt
    13621 tatagaggaa taagacacgc taaaggtctt ccattaagag gacaaagaac taagactaat
    13681 gctagaacta gaaaaggtcc tagaaaaaca gtatctcgta aaaagaaaaa ataaataaat
    13741 aataactaga tgaaggaggg aaaaggaaaa tggctaaacc aaaaaagaaa gttacacgta
    13801 ttagaagaag agaacgtaaa aatatagaac gtggtcatgc tcatatacaa tcaactttca
    13861 ataatacaat aataacttta actgacgttc acggaaatgc tatatcttgg gcaagttctg
    13921 gacaattagg attcaaagga tcaagaaaat caactccatt tgcatctcaa atggctgctg
    13981 aaacagctgc aaaagctgcg atggaacacg gactaaaaag tgttgaggta ttcgtaaagg
    14041 ggccaggttc aggaagagaa gctgcaataa gagctttaca agcaactgga ctagaagtaa
    14101 ctatgataaa agacgttact ccaatcccac ataacggatg cagaccacca aagagaagaa
    14161 gagtgtaatt aataagagta caataggagg tgtagataaa tggcaagata tacaggtgca
    14221 tcatgtagac aatgccgtag agagggaatg aaattattcc ttaaaggtga tagatgttat
    14281 acagacaaat gtgctatagt aaaaagaaac tatgctccag gtcaacatgg ccaaggaaga
    14341 aagaaagttt ctaactatgg attacaatta agagaaaaac aaaaagttaa aagaatatat
    14401 ggagttttag agactcaatt tagaaattta tatgaacgtg ctgaaaatat gcctggtaaa
    14461 gcaggtgaga acttattaag tttattagag agaagattag ataatgtagt ttacagaatg
    14521 ggactagcat cttctagaaa agaagctaga caattagtga ctcatggtca tttcacttta
    14581 aatggaaata aagtagacat accttcatta atagttaagg ttggagatgt tatagaagtt
    14641 aaagagaaat caagatcttc tgcaaaattc aaaaatttag tagaagttaa ctcaagaata
    14701 gctcctaagt ggttagaagc taatgtagaa ggaatgacag caaaagtagt tggtgttcca
    14761 acaagagaag atatagatct tgagatagca gagcacttaa tcatagaact ttactctaaa
    14821 taataagcac acttttaaaa attattttaa aattttgttt accctcagtg gattactgaa
    14881 ttttaaggag ggttttgtcc atgatagaaa tagaaaagcc aaaagtagat atagttgagc
    14941 ttagcgaaga ctatagatat ggtaagtttg ttatagagcc tctagaaaga ggatatggaa
    15001 taactatagg taacgcatta agaagaatat tattatcatc attaccaggt gtagcagtga
    15061 atgctataaa aatagatgga gttcttcatg aattttcaac aatacctggt gttaaagaag
    15121 atgttactga gataatatta actttaaaag agctttcagc aactatagat ggtgaaggaa
    15181 gtagaacact taaaatagaa gctcaaggac catgctctat cacaggtgca gatataatct
    15241 gtcctccaga tgttgaaata ttaagtaaag atttagcaat agctacatta gatgataatg
    15301 ctaaacttaa tatggagata tttgtagata aaggtagagg ttatgtttct gctgaagaaa
    15361 ataaaacaga gaatgttcca ataggtgttt tacctgtgga ttcaatatat actcctgttg
    15421 agaaggttag ttatcatgtg gaaaacacaa gagttggtca aaaaacagat tatgataaat
    15481 tagtactaga agtttggact aatggtagta taaatcctca agagggaata tcattagctg
    15541 caaaggtatt agttgagcat ttaaacttat ttatagactt aactgaacat gtaagtagtg
    15601 ttgaaatcat ggtagaaaaa gaagaagatc aaaaagaaaa agttcttgaa atgactatag
    15661 aagaattaga tttatcagtt agatcatata actgtttaaa gagagcggga attaatacag
    15721 ttgaagaatt agctaataaa tctgaggatg atatgatgaa ggttagaaac ctaggtaaga
    15781 agtcattaga agaggtaata caaaaactag aagaacttgg attgggatta aaaccaagtg
    15841 aagaatagcg agcaaaggag ggataagaat ggctaagtac cgtaaattag gacgtgaaac
    15901 agctcacaga aaccttatgt taagaaactt agtaacttgc ttactaagaa gtggaagaat
    15961 agaaactaca gtgactagag cgaaagaaac tcgtagaatg gctgaaaaga tgataactct
    16021 tgctaagaga ggagatcttc atgctagaag acaagtttta gcttatgtta tggatgaaac
    16081 agtagttaat aacttattca cagatttagc tccaaaatat gctgagagaa atggtggata
    16141 cactagaata ataaaaatag ggccaagaaa aggcgatgct gctgaaatgg cttttataga
    16201 attagtatag taaggaaagg attaggcttg atggcttaat ctttttttta tttttttgac
    16261 taaggtatga tataataatg tgtaaaatga tttttataag ttattgctta ctaaaaggag
    16321 tatgagttaa tggataatat agtaaaggta aataatattt cgtttgagta tattacagat
    16381 gaagcaaaac ttaaagcaat agataattta agcctagatg ttaaaaaagg agaatttgtt
    16441 gcgataatag gacataatgg ttctggtaag tctactttat ctaaaaactt aaatgctatt
    16501 cttatgccca ctgaaggaaa tattcttatt gatgatatgg atactaaaga agaagaaaga
    16561 ttatgggata taagacaaac tgcaggcatg gtatttcaaa atccagataa tcaaatagtt
    16621 gctactatag tagaagaaga cgttgcattt ggacctgaga acttaggtat agaaccaaaa
    16681 gaaataagac gaattgtaga ggagtcttta aaaagtgtag gtatgtatga tttaagagat
    16741 agacagcctc atttgttatc aggaggtcaa aagcaaagag ttgcaatagc aggaattatt
    16801 gctatgaggc ctaaatgtat aatctttgat gaagcaacag caatgttaga tccatctgga
    16861 agaaaagaag ttatgaaaac aataaaaaga cttaataagg aagaaaatat aactgttata
    16921 catataacgc actttatgga agaagcagta gaagctgata gagttgtagt tatggaaaaa
    16981 ggaaagaaaa tcttagaggg aactcctaga gaagtattca gtaaaataaa gatgttaaag
    17041 gaaatcggtt tagatgtacc ttgtatgaca gagttatcta gtttattaat agaagaaggt
    17101 ataaatatta gtagtgatat attaactgtg gatgagatgg tgatggaatt atgtcaatta
    17161 tagtaaagaa tttaacacat atatataatg aagggatgcc ttttgcaagt aaggcacttg
    17221 atgatgtttc ttttgagatt aaagatagag attttgttgg tcttataggt catacaggct
    17281 caggaaaatc tacattaata caacatttaa atggattact aaagccttcc tcaggagaaa
    17341 tatttataaa tgattttaat ataacagata aaaacttgaa tttaactgag attagaaaaa
    17401 gagtaggggt tgtatttcaa tatccagaat accaattgtt tgaagaaacg attgataaag
    17461 acatagcttt tggaccctct aatttaggct tagaggagtc tgagatacat aacagggtaa
    17521 aagcatcaat ggaagctgta ggacttgatt atgagggatt taaagacaaa tctccttttg
    17581 aattatctgg gggacaaaag cgtagagtag caattgctgg agttatagcc atgaacccag
    17641 aagttctcat attggatgaa ccaactgctg gtcttgaccc tggtggaaga gatgaaattt
    17701 ttaacttaat aaaagactta catgaaaaaa agaatatgac tataatacta tcatcacata
    17761 gtatggatga tatggcaaag ttagcaaaaa ctttaattgt tatgaatcat ggtagcgtag
    17821 aatttatggg aactcctaga gaagtattta aatcaaatgc tagtaaatta aaagatatag
    17881 gattagatat tccacaagtt ttagagcttg cattgaaatt gagagaaaaa ggctttgaca
    17941 tcagtgagga tatattgact ttagaagaag caaaacagga aatattaaaa gttgtgagag
    18001 gacgaggatt atgttaaaag atataactat agggcaatac tacccaacaa gttctgctat
    18061 tcataaatta gatccaagga taaagcttgt agcgacaatt gtatttatgg tatctatatt
    18121 tgtagtaaat aaattttggc cttatatagt agttttatta tgtttattag ctatgataaa
    18181 attggctaat ataccagtca aatatattgt taagggtgtt aaacctctta aatggattat
    18241 tttgtttaca tttcttataa atattttttt cttaccaggt gatgaaatat ggtcatttgg
    18301 atttttagct attacaaaac agggtctaag acaagcaatt tttatggcaa taagattaat
    18361 atttttagta gttggtacat cattgcttac tttaacaact tcaccaatag aattaactga
    18421 tggaatagag agattgttga atccatttaa gaaaattggt ttgccagttc atgaacttgc
    18481 aatgatgatg acaattgctt tacgttttat tcctacattg ttagatgaga cagacaaaat
    18541 aatgaaggct cagatgtcta gaggtgcaga ttttgaaagt aagaatctta taaatagagc
    18601 aaagaattta gtaccacttt tggtaccttt atttgtaagt gcatttagaa gagctgatga
    18661 attggctatg gccatggagg ccagatgtta cagaggtgga cataatagga ctaagatgag
    18721 agagtctgtt atatcaagaa gggattatat ggcatgtgta tttcaggttg tttatctggg
    18781 agcaattata gctactagat ttatagcaat ttaattaata agttatagat ataatgaggt
    18841 aaagtatgag aaatataaaa attaaaatcc aatacaatgg taagaattat tgtggatggc
    18901 aaaagcaacc tgattcttta gggatacaag gtacaattga aagggctata tatgatataa
    18961 caaaagaaga aaccagtctt atagggtctg gtagaactga ttcaggagtt catgctattg
    19021 gtcagattgc aaattttaaa attaattcag gtataagtat agaaagtata ccaatggcac
    19081 taaatgccaa gttgccaaaa gacatatcag ttatagaagc atgtgaagta aatgatgatt
    19141 ttcactccag atacagtgca aaaggtaaaa catataaata tttagtatat aatagcaagt
    19201 ttagaaatcc aatacttagt gagatatcat atcaagtaaa atatgaactt gattttgata
    19261 aaatgtgttc agaagcaaaa agtttattag gaacacatga ttttaaaggt tttatgagtt
    19321 ctggttcatc tgtaaaagat acagttagaa cgatatatga tattggtata agtaaaaaag
    19381 atgacttgat tacttttgag attagtggta atggtttttt atataacatg gtgaggatta
    19441 ttgttggaac acttgttgat atgggtcgtg gtagaattaa cgaaccattt ttagatataa
    19501 tacaatcaaa aactaggtca agatgtggac atacagctcc agcacaagga ttatttctca
    19561 aaaaagttca ttattaactt gacacaccag gctacatgta ttaaaatata tgagaatgtg
    19621 ttaataagtc cacttgcccc ggacttgaca taaacggtaa aaaaatttta tgaaaagtag
    19681 ttaaggaggg acagttatga aaagttatat agctaagcca gctgatgtac aaagaaaatg
    19741 gtacttagtt gatgctgaag gaaaaacatt aggtcgttta gcaacagaaa ttgcgacagt
    19801 attgagaggt aaacataaac caacatttac tcctcacgtt gatggtggag attttgttgt
    19861 tgtagtaaat gcagaaaaaa tagttttaag tggtaagaaa ttagatcaaa aatattacag
    19921 ataccatact ggttatgtag gtggattaaa agaaatatct tacagagata tgatggataa
    19981 gaaaccagaa gaagttatat cacatgctgt aagcggtatg ttacctaaaa ataaattaag
    20041 aagcagaatg atgactagat taagagtatt tgcaggtgct gagcacactc atgcagctca
    20101 aaatccagaa gttttaaact ttaaataaga ttaataggtg aaaggaggag tttataatgg
    20161 ctaacgttca atattatgga actggaagaa gaaaaagttc tgttgctaga gtaagactag
    20221 ttgcaggtga aggaaatata ttagtaaatg gaagagcatt agaaaattat tttaattatg
    20281 agacattaat aagagatgtt aaacaaccat tagttttaac tggtaatgaa aataaatatg
    20341 atgttatagt aaaagttgaa ggtggaggat tcactggaca agctggagct ataagacatg
    20401 gaatatctag agctttatta aaagctgatt tagatttaag acctgcttta aagaaagaag
    20461 gtttcttaac tagagatgca agaatgaagg aaagaaagaa atacggatta aaagcagcaa
    20521 gaagagctcc acaattctca aaaagataat tacttatttt tttggaaaag caaaatcctt
    20581 tatttactgt tattcagaaa gtattggtat tttaaaaatg ttgggttaag ttaattattg
    20641 atatataata aaataataag atatcttatt aggatgtttt tcattaagaa gaacatcctt
    20701 tttattttga ctatttaata aaaaacatat gctaataaca tttaaatttt atttttataa
    20761 tattgtaatt taaaagttta tataaggtta tatattttaa gatattattt aacaatataa
    20821 attctgaata tacgttatca aagtttataa tataaactaa gtataattta ttgtatagta
    20881 ttgaatgtta gataaacata gtgaattaaa tagggacaga aatataatat cattacataa
    20941 taatatatta ataccaataa ataaagatat atcaatatta aaaaaattta aatgtttgta
    21001 ctaatatatg gaatattata gtgtttttat aagtatacat atacagggtg atgttgtgag
    21061 aaagtacata aaacatataa tttttagttt tgcaatgata tgtctagtag tagtatccat
    21121 atttgaaatt aaaaatattt ctgaagatgt tatcaagtat atgccagtaa caaacaaaac
    21181 tataatttta gatgctggtc atggaggcat tgatccaggt gcattaaata aggataagag
    21241 tacatctgaa aaggatatta acctagcaat aacacttaag cttagagagc ttatagaatc
    21301 aagtggtggc cttgtaatat taactcgaga agatgacagt agcctttata aagaagaaaa
    21361 taataaaact acaagacaaa aatataatga gaatttgaaa aatagaaaag aaataatatc
    21421 taattctaat gccaatatgt ttgtctctat acatcttaat gcatttgaac aatcaaaata
    21481 ctatggagct caaacttttt atcctaaaga caaacaagac agtaaagaat tatcgaagtg
    21541 tattcaagaa gaacttaaaa gagtagtaga taagacaaac aacagagaag tcaaaccaag
    21601 ggatgatata tatcttttga aagaaaataa tattccatca gtactgatag aatgtggttt
    21661 tttatcaaat gaaaaagagt gtaaactctt aactgatgaa acatatcaag aaaaaatagc
    21721 atgggcaatc tacataggaa tacaaaaata tttaagttga aataactata aaaataggtc
    21781 taaatatgta aatagcttgt attaaagcag ttaaaatgca ttaatatagg ctatttttat
    21841 tttgacaaaa aaatatttaa aataaaagtt aaaaagttgt tgacttagaa taatatagat
    21901 gatattatat atgagtgccc aaaaggagca ccaaaataag ac
//
LOCUS       DACTZW010000073        21787 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.073, whole genome shotgun sequence.
ACCESSION   DACTZW010000073 DACTZW010000000
VERSION     DACTZW010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21787
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.073"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            167..1618
                     /locus_tag="JAM15_14060"
     CDS             167..1618
                     /locus_tag="JAM15_14060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HAT6799381.1"
                     /translation="MDFFNGILTSINNAVVFVNNYLWSYILIIMLVVIGIYFTIKTNF
                     VQFRYFIEMFRLLGDGTANKNAKKEGKISSFQAFCISTSSRVGTGNIAGIAIAVVAGG
                     PGAVFWMWLIALIGSASSFVESTLAQIYKVKDGQAFRGGPAYYMEQGLNKKWMGILFS
                     ILITICYGFVFNAVQANTVSLAFNNAFGISKMAMGIGLGILTAIVIFGGVHRVAKVSE
                     IIVPVFAGLYILVALAIVVMNITEIPSVIALIVESAFDFKGMAIGTFMGVVMTGVKRG
                     LFSNEAGMGSAPNAAATAHVTHPVKQGLIQSLGVFTDTIIICSCTAFMVLLYSGYSSS
                     GATGIELAQEALTHHIGPVGNIFIAVCIFLFAFSSIVGNYYYGESNMEFMSGSKTKLN
                     VFRVFVVGMVLFGSLTQVDVVWNLADLFMALMAIINLIAIALLGKYAFIALKDYTSQK
                     KSGIKDPVFIADEIEGLEKVSEWHRELSEEHLG"
     gene            complement(1838..2299)
                     /locus_tag="JAM15_14065"
     CDS             complement(1838..2299)
                     /locus_tag="JAM15_14065"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HAT6799382.1"
                     /translation="MIYEGKLIGKDLKIGIINSRFNEFITSKLLSGAEDCLLRHDVSP
                     ENIEIVWVPGAFEIPLVAQKMAKSGKYDAIICLGCVIRGATSHYDYVCSEVSKGIAKV
                     SLDSELPVIFGIVTTENIEQAIERAGTKAGNKGYDCAMNALEMANLFKSLN"
     gene            complement(2405..3598)
                     /locus_tag="JAM15_14070"
     CDS             complement(2405..3598)
                     /locus_tag="JAM15_14070"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HAT6799383.1"
                     /translation="MFNTIEEAIEDIKNGKMVIVVDDESRENEGDLLMAAEMATPESI
                     NFMATYGRGLICLPATEKKFKSLNIPLMVRENTDTFQTAFTVTIDGADTLTGISAYER
                     AETVKLFCDENSTSKDFKTPGHIFPLIAKTGGVLVRDGHTEASVDLARLAGFKEIGLI
                     CEIMKDDGTMARVDDLMIFKEKHNLKIITIKDLIEYRKINETTIEKVSSAFLPTKYGN
                     FEIIGYRDTYSNEEHIALTYGNINIENTLVRLHSECLTGDVFHSLKCDCGLQLESSMK
                     KIVENGSGVLIYMKQEGRGIGLLNKIKAYKLQEEGYDTVEANLMLGFEEDMRDFYMAA
                     QILKNLNIKSINLLSNNPDKINQLEKYGIKIENRIPINEEINDFNKLYLKTKKDKMGH
                     LLDII"
     gene            complement(3621..4286)
                     /locus_tag="JAM15_14075"
     CDS             complement(3621..4286)
                     /locus_tag="JAM15_14075"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HAT6799384.1"
                     /translation="MFTGIVEEVGILRKITANGKSGKVTILSNKILDGTNLGDSIAVN
                     GVCLTVSNLGKNEFTADVMMETIRSTNLGLLNANDKVNLERAMSLSSRFGGHIVTGHV
                     DGKGTICKFEKDENAVLVSIRPNKKLLSSMILKGSVAIDGVSLTISYLDDEIFKVSII
                     PHTKINTILLTKNVGDFVNLESDVIGKYVNNFMANNYKELNSNSSNHKSNIDKDFLFK
                     NGF"
     gene            complement(4320..5423)
                     /gene="ribD"
                     /locus_tag="JAM15_14080"
     CDS             complement(4320..5423)
                     /gene="ribD"
                     /locus_tag="JAM15_14080"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HAT6799385.1"
                     /translation="MNQKEKDIYYMKKAIELAKNGEGFVNPNPLVGCVIVKDSNIIGK
                     GYHEKFGSNHAEVNAINSAKQSLKDSTLYVNLEPCSHYGKTPPCVDKIIQNKIKRVVI
                     STLDPNPLVCGNGVKKLKDNNIDVTVGILEDEARDLNEAFFYHIKNKRPLCIVKSAVS
                     LDGKIATKSLESKWISNESSRYLTHKYRNKYQSIMVGINTVLNDNPLLTCRLNQEKVS
                     HPTRIVIDTHLKLPLNSNLVKDKTSKTIVFTCCKESIKLSMLKENNVETIISPSKNNL
                     VDLEFVMYKLGELNIDSVLVEGGATLNDSLFRNKLVDKVKLFLSPKIIGGKDAPTFVS
                     GEGINHLSDSTQLTINNVTLIDGDILIESDVLN"
     regulatory      complement(5555..5676)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            5865..8348
                     /gene="recQ"
                     /locus_tag="JAM15_14085"
     CDS             5865..8348
                     /gene="recQ"
                     /locus_tag="JAM15_14085"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HAT6799386.1"
                     /translation="MNKKLLEILSKYYGYTSFRKGQESIINSILSEKDVLAIMPTGGG
                     KSICYQIPALILDGMTIVISPLISLMKDQVDALKTMGISAAFINSSLSSKEFNEILNN
                     IRKNNYKILYIAPERLDAQEFIELINNNNVSQVAIDEAHCVSQWGHDFRLSYRRISDF
                     IKNLPKRPIVTAFTATASEEVRTDIINLLCLENPDYYITGFDRENLSINIVKSSSKNK
                     YILDYIQNHKNESGIIYVATRKEVENIYNGLSKRNISVSKYHAGLSKNERSKNQEDFI
                     NDNVDIMVATNAFGMGIDKPNIRWVIHYNMPQSIENYYQEIGRAGRDGEKSECVLLFS
                     PGDVHIQKYLIDIGVENPERKLFQHKKLQYMIDLVYSNSCYRKTILSYFGENYIDNCN
                     NCSNCLVEGEIVDKTIDAQKVISCVARMKRSYGVTTIVDVLRGSKNKKILQLGLNTLS
                     TYNIMRDYSSEDLKNFVNTLVSHGFLDLVETLGNGNRGSFPTIRLNEMSMKVLKGEVK
                     VEFKEIVMTKSLEVEDELYNALRELRHSIASEERIAPYMVFGDGTLRAMSSSYPINKE
                     EMLDISGVGEIKYQKYGRDFEAVIKEYVEKNNINKKIDEKNVDLKNVNSDFLEVNTDK
                     VLYEKLLVIREEYATKEKLPAYMILANKALKEISGRYPLDEEQLKDISGIGGVKFEKY
                     GASILAEVNKYVKENNINVIWEKKGKRKLILDGESRKNNEIALDLLNQGKDIQSISQE
                     IEVSLSTIIGYVHDYVKDGHSISFELGLENFYNEDKKKMILEVCEKVGYDNLNNIKRK
                     LPDSIKYENIRAVILDSYLENLKKNIIAE"
     regulatory      8437..8548
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            8690..9991
                     /gene="thiC"
                     /locus_tag="JAM15_14090"
     CDS             8690..9991
                     /gene="thiC"
                     /locus_tag="JAM15_14090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010074607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HAT6799387.1"
                     /translation="MNYTTQMDAARKGIITKEMEIVSQKEQVDVNELRELIANGQVVI
                     PANKNHKSLSAEGVGKNLRTKINVNLGISRDCKDIEKELEKVRVAIDMKAEAIMDLSN
                     YGKTREFREKVVEMSPAMIGSVPMYDAVGYLEKELKDITEEEFLNVIRQHAIDGVDFI
                     TIHAGLTRSVCQKIKNHERLTHIVSRGGSLLFAWMELNNKENPIYTNFDKILDICEEY
                     DVTLSLGDACRPGCIKDSTDGVQIQELVVLGELTKRAWERNVQVMIEGPGHMAIDEIE
                     ANVVLEKRLCHGAPFYVLGPLVTDIAPGYDHITSAIGGALACAKGVDFLCYVTPAEHL
                     RLPNLDDMKEGIIAAKIAAHAGDIAKNVKGAREWDNKMSKARADLDWCEMFRLAIDPE
                     KAKRYRDESTPTHEDSCTMCGKMCSMRTVKKILNNEELNLI"
     gene            10045..10239
                     /gene="thiS"
                     /locus_tag="JAM15_14095"
     CDS             10045..10239
                     /gene="thiS"
                     /locus_tag="JAM15_14095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HAT6799388.1"
                     /translation="MKVNGKEIEFEKDLTVIDLLNKYNLKSDRVVVEVNLEIIEESNY
                     NTYVLKDEDIVELISFIGGG"
     gene            10226..11035
                     /gene="thiF"
                     /locus_tag="JAM15_14100"
     CDS             10226..11035
                     /gene="thiF"
                     /locus_tag="JAM15_14100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine biosynthesis protein ThiF"
                     /protein_id="HAT6799389.1"
                     /translation="MEVVKIKIFVNELLTDVEENTTAYKVRDSYNNKCDVLVLNGYPI
                     KTDMPLCENDKLTLIQKGVKPSLDELESLLIARHTPNIHNKLKKGKVAILGLGGLGSN
                     IAISLARIGVGELLLIDYDVVEPSNLNRQQYFIDDIGKLKTDAMIENIKKINPFIKLN
                     KRDIFLNKNNMDTIKDSDLIIEAFDDASCKAQVCNYVLINLKDKYLIASSGMAGYYDS
                     NIITTKKIKDRFYICGDFVNEAKFGEGLMAPRVAICANHMANLATQILIDM"
     gene            11098..11868
                     /locus_tag="JAM15_14105"
     CDS             11098..11868
                     /locus_tag="JAM15_14105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="HAT6799390.1"
                     /translation="MDKLVLGGHEFNSRLLVGTGKYGSNNILPEVIKESGSEIITMAL
                     RRVDLDNKQENILTYIPKEMTILPNTSGATNAEEAVRIARISRKMGCGDFIKIEVISD
                     TRYLLPDNEETIKATKILANEGFIVLPYMTPDLYAGRRLIEANAAAVMPLGAPIGSNR
                     GLQMKEMIRIMIDELDIPIIVDAGIGKPSQAMEAMEMGADAVLVNTAIASAGDPVQMA
                     RAFKLAVEGGREAYIAKTGNVSEFANASSPLTGFLGNL"
     gene            11885..12988
                     /gene="thiH"
                     /locus_tag="JAM15_14110"
     CDS             11885..12988
                     /gene="thiH"
                     /locus_tag="JAM15_14110"
                     /EC_number="4.1.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminoacetate synthase ThiH"
                     /protein_id="HAT6799391.1"
                     /translation="MSFYDVIEKYRDFDFDGYLNNVTDNDVLRSLSKDKLEDFDILNL
                     LSKTAVKHLEDMAQKAHKLSVQYFGKTVCLYTPMYIANYCVNQCVYCSYNIKSGIKRK
                     KLTMDEIREEGEAISKEGFKHLLVLTGESSFHSSVEYIGEAIEILREKFPSIGIEVYP
                     MEVEEYKYIVDKGVEGLTVYQETYDEEIYKRVHIKGPKSNYKFRLDAPERGAKAGMRT
                     LSIGALLGLNDFRKETFFTILHGKYLKTKYPHIELSYSTPRMRPFKGCFEELVDISDT
                     DLVQAMVCMRLFDPHAAINISTRENLEMRSHIIPLGVTKLSAGVSTDVGGHSQDEHDT
                     AQFKINDESTVKDVEKMLNSIGYQHVFKDWERF"
     gene            12989..13678
                     /locus_tag="JAM15_14115"
     CDS             12989..13678
                     /locus_tag="JAM15_14115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HAT6799392.1"
                     /translation="MYLITNRKLCSEERYLEVIKESILSGVENIIIREKDLEYQELRK
                     LYMKIKTKINCIDFQEQISDESLKTNINQKECRNKFKVNFIINSNIEFFEKVDCQGIH
                     LPFKLFLNLIENKYNFNENKILGLSLHKVEEVDYLEKLIRNQNIKIDYITLSHIYETK
                     CKEGLNPKGIELLKEAKKITDIKIIALGGILPSNVKETLKYCDDFAIMSTIMRSKDIK
                     KTISNYNEKLN"
     gene            13866..15260
                     /gene="yfcC"
                     /locus_tag="JAM15_14120"
     CDS             13866..15260
                     /gene="yfcC"
                     /locus_tag="JAM15_14120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HAT6799393.1"
                     /translation="MTDSKKKRFIIPHTFTIIFLLIVLMAILTWIVPSGEFSREDVEG
                     RMVVVPGTYQSVESNPQGFADVFKAPIEGFIDSAEVVGFVLIVGGAFGIVNRTGAIEA
                     GIASVISKFKGKELLIIPISMILFGLGGTTFGMAEETLPFYMIFVPLMTSLGYDSLTA
                     IAIVFIGAAAGAAASTINPFSVGIAQALAQLAPGSGVTYRVVIFIAYILISIAFVMYY
                     AKKVKENPESSIVYEIDKNNKSILNQTSTEIKEFTFKEVSVLAIFGIGMAIMIWGVLS
                     QGWYIPEISMCFAAIGVLSGLVGRLSQIEISESFIDGAKDLASAALAIALARGIVIIA
                     QNGFIIDTILNSAAAFLGGLPKVIFVYLSFFLEAALAFLIPSSSGLASLTVPVLAPLG
                     DLVNISAQVIVTAYQFGVGLTNFITPTSGVLMGALAVAHIPFSKWVRFIMPILLILTV
                     VSLVFLTIGIYIGF"
     gene            15777..17144
                     /locus_tag="JAM15_14125"
     CDS             15777..17144
                     /locus_tag="JAM15_14125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HAT6799394.1"
                     /translation="MGLKEFDFIEESIDMLRTMSPTLETISDEIEEYFENILDEKNQE
                     YINVTSRIKSESSLREKIIRNRYLKKYGEASNLIHNVSDLIGLRIECRFIEDENKIYR
                     LLRRYFNKTDDKINYYNKENKNIKLKLSERQPNKQKNGFEIYKIDGVFAYLDREVKFE
                     LQIKSLVNVFWSEIEHKIIYKNNTYLLADKFIKDMMDSIKNNLTMIDNQLLSIYKNFH
                     SGKSFNMKVSKKEIEKLFAKLVYDAFSEKMNKSIGFVVDFKKPCETILNYSFNKQDIS
                     DEVLGNFMLDEFARLNEIVNKDIDFNEQIEFEREPTFDDKFCKDLGNHFRSRLNTEFP
                     WNLFFRILFEIEPYNNTKDFENFVEFIKENVLLEENREQLLCQFEEDSKLIIEDIYDC
                     IFNSISEIDSVEILYNYNLEKINFTSSEIINCICREYECYGEYLEEKEKLMNTFKEKL
                     IQIFE"
     gene            17169..17777
                     /locus_tag="JAM15_14130"
     CDS             17169..17777
                     /locus_tag="JAM15_14130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase"
                     /protein_id="HAT6799395.1"
                     /translation="MRHFSNIYELSKIILEEAICIEKTGVILAGGKNSRMGRDKAFLE
                     LHDKLFIEIAIEAFKNFDELIIISNNEELYSKYDIKVYNDIVKDVGPIGGIYTALEYA
                     KYDIVTIACDMPYLNNQIVERIANKMNDKSVISVTNGKLQPLCSGYKKSIINKVSLCI
                     RENDLKLRSFIDKIDKSYIHFDEEDLFLNVNTVDEYEKLTKV"
     gene            17825..18196
                     /locus_tag="JAM15_14135"
     CDS             17825..18196
                     /locus_tag="JAM15_14135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HAT6799396.1"
                     /translation="MNLLKCDSWAVILNNSDKESKAYKILDELKRNMYKVVAIDEEKK
                     TIEGIDVYECLKDVPHNIDVVAIIDKQSKMDVILEEVELLDIQNMWFEKGSFSEMMIK
                     KTKDLKLNIEYNLSLYDELTR"
     gene            18375..18713
                     /locus_tag="JAM15_14140"
     CDS             18375..18713
                     /locus_tag="JAM15_14140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HAT6799397.1"
                     /translation="MLIVTTEKVEGKKISKVLGLVRGSTIRAKHVGKDIGASFKNLVG
                     GELTGYNEMLTEARQIAIGRMVEDAEAKGANAVIAFRLSSASVMQGAAEMLAYGTAVV
                     LEDDNSILEK"
     gene            19180..19683
                     /locus_tag="JAM15_14145"
     CDS             19180..19683
                     /locus_tag="JAM15_14145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MogA/MoaB family molybdenum cofactor
                     biosynthesis protein"
                     /protein_id="HAT6799398.1"
                     /translation="MFNVAIITLSDKGYEGKREDITGKKLTEFVENTGAYKVTEYVLI
                     KDDKEMLKENIIRLCNSNKIDLILTNGGTGFSKRDITPEATKEVLEKEIPGLSEYMRM
                     KSTEITKKAILSRGVSGIRNNSIIINLPGSPKGAVENLSFIIDVLDHGIEVLRGEATE
                     CATKKSE"
     gene            19730..20689
                     /gene="moaA"
                     /locus_tag="JAM15_14150"
     CDS             19730..20689
                     /gene="moaA"
                     /locus_tag="JAM15_14150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HAT6799399.1"
                     /translation="MIDKYGRKIDYLRISLTDKCNLRCVYCMPPDVKFDKNYINENLS
                     FEDYKFIIKAMAEQGITKIRFTGGEPLLYPKLNELIKFTKEECGINNIGMTTNAIGLS
                     DRIFELEKCGLNKVNISLDSLKEYKYKSVTRGGNLKDVLKSIESCLNLGIKVKLNCVA
                     ISGFNDDELKDFMFLTVKSPIDVRFIELMPLGEANRVYKKGYFNVKEMIEKIYGLYKV
                     KNDEKSTAEYYMFKGAKGRIGIITPLSCSFCNTCNRIRLTSSGAIKLCLHSKEEIDIK
                     PFLHKPLLFRESMKDIIKQKPEKHHLIENKCSDTNRRMYEIGG"
     gene            20693..21163
                     /gene="moaC"
                     /locus_tag="JAM15_14155"
     CDS             20693..21163
                     /gene="moaC"
                     /locus_tag="JAM15_14155"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HAT6799400.1"
                     /translation="MLTHINEKGYAKMVDISEKDDTKRTAIATATITLSKEALEKVKN
                     GQIKKGDVLSVAQVAGIMGAKNTSSNIPMCHQIKLVGCDLEFDVDDYMSAIKIYATCK
                     SLGKTGVEMEALNACSLAALTIYDMCKAVDKKMVISNIHLVEKTGGKSGDFKFE"
     gene            21199..21630
                     /locus_tag="JAM15_14160"
     CDS             21199..21630
                     /locus_tag="JAM15_14160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MOSC domain-containing protein"
                     /protein_id="HAT6799401.1"
                     /translation="MAKVVSINISEKKGVIKVPVPCAELKINHGIVGDAHAGNWHRQI
                     SLLGKESIDKMKMKGFDQLKYGDFAENVTTEGIEVFSLPVGTKLRIGQCEVEVTQIGK
                     KCHNGCEIKKLTGDCVMPREGIFVKVLKEGIINVNDSIDVI"
BASE COUNT         8399 a         2344 c         3763 g         7281 t
ORIGIN      
        1 gaatataaaa ctgcaatata ttaaaaaaat tattcatttt aaaccttgta atttgatttt
       61 ataaatatta taattaaatt aatgaatttt taacaaggaa ttattcattt ttttgatttt
      121 aagatttatt gagaaaacaa aactaaatag gggggtaatt aatataatgg attttttcaa
      181 tggtatttta acgagtatta acaatgcagt agtatttgta aacaattact tatggtcgta
      241 tatcttaatt ataatgttag ttgtaattgg tatttacttt actattaaaa caaattttgt
      301 acaattcaga tattttatag aaatgtttag acttctgggt gatggtacag cgaataaaaa
      361 tgcaaaaaag gaaggaaaaa tctcttcatt tcaagcattt tgtataagta catcttcaag
      421 agttggaact ggaaatatag ctggaatagc aattgcagtg gtagcagggg gacctggtgc
      481 tgtattttgg atgtggctta tagcattaat tggttctgca tcaagctttg ttgagagtac
      541 attagctcag atttacaaag tgaaagatgg tcaagctttt agaggtggac cagcgtatta
      601 tatggaacaa ggtctaaata aaaaatggat gggtatttta ttctcaatac ttataactat
      661 atgttatggt tttgtattta atgcagttca agcaaatact gtttcacttg catttaataa
      721 tgcatttgga ataagtaaaa tggctatggg aataggtctt ggaattttaa ctgcaatagt
      781 tatttttggt ggagtgcata gagttgcaaa agtttctgaa ataatagttc ctgtatttgc
      841 aggattatat atattagttg ctttggctat agttgtaatg aatataacag agataccaag
      901 tgttatagca ttgatagttg aaagtgcatt tgattttaaa ggaatggcga ttggtacatt
      961 tatgggagtt gtaatgactg gagtgaagag aggtctattt tctaatgaag caggtatggg
     1021 tagtgctcct aatgctgctg caacagcaca tgtaactcat cctgtaaaac aaggtttaat
     1081 tcaatcttta ggtgttttta cagatactat aataatatgt agttgtacag cattcatggt
     1141 attattatat tcaggttata gtagtagtgg agcaactgga attgaattag ctcaagaagc
     1201 tttaactcat catataggac cagttggaaa tatatttata gcagtttgta tattcttgtt
     1261 tgcatttagt tctatagttg gtaattacta ttatggtgaa tcaaatatgg agtttatgag
     1321 tggaagtaag actaaactta atgtatttag agtttttgtt gtaggcatgg ttttatttgg
     1381 ttcacttact caagtagatg tagtttggaa tcttgcagac ttatttatgg cattgatggc
     1441 gataataaac ttaatagcaa tagcactttt aggaaaatat gcatttattg ctttaaaaga
     1501 ttatacaagt caaaaaaaat caggaataaa agaccctgtg tttattgcag atgaaataga
     1561 aggcctagaa aaggtatcag agtggcatag ggaattatct gaggaacatt taggataaaa
     1621 aatagtataa aattataaaa ccattttgaa agactagagt atgtatatgc tttatatgaa
     1681 tataatattg aattaattta tattactgga atttttaatt ccagtaatat ttttttatta
     1741 tataatttag ctttattaaa agtttttatt attaaaaata gcttatttat cgtaaagtga
     1801 atgatattgg ttttttaatt attatgaatg ttggtattta atttaaagac ttaaataaat
     1861 ttgccatttc tagcgcattc atagcacaat cataaccttt atttccagct tttgtacctg
     1921 ctctttcaat agcttgttca atattttctg tagttacgat tccaaatata acaggtaatt
     1981 cactgtctaa agatactttt gctatccctt tagagacttc actacataca taatcataat
     2041 gagaagtagc ccctcttata acacagccta aacagattat agcatcatac ttaccacttt
     2101 tagccatttt ttgagcaaca agaggaatct caaaagctcc aggtacccaa actatttcta
     2161 tattttctgg agaaacgtca tgtcttaaaa gacagtcttc agctcctgat aaaagttttg
     2221 atgttataaa ttcattaaaa cgagaattta ttatacctat ttttaaatct tttccaataa
     2281 gttttccttc atatatcatt tttatttcct ccaattttat ttatgttata gatttatatt
     2341 tataaatatc tttaatttta attataaaaa actacttagt agaaaaatat catcatataa
     2401 tcatttatat aatatctaaa agatgtccca ttttatcttt tttagttttt aaatatagct
     2461 tattaaagtc attaatttct tcattaatag ggattctatt ttcgattttt attccatatt
     2521 tctctaattg atttatttta tccgggttat tacttaaaag atttatactt tttatgttta
     2581 aattttttaa tatttgagca gccatataga aatctctcat atcttcttca aatccaagca
     2641 ttaaatttgc ttcaacagta tcgtaacctt cttcttgaag tttataagcc ttaattttat
     2701 ttaaaaggcc aatacctcta ccttcttgct tcatataaat taaaactcca cttccatttt
     2761 ccacaatttt cttcatagaa gattctagct gtaatccaca atcacatttt agagagtgga
     2821 acacatctcc tgttaaacat tcagaatgaa gtctaactag agtattttct atatttatat
     2881 ttccataagt aagggcaatg tgttcttcat ttgaataagt atctctatat cctatgattt
     2941 caaaatttcc atattttgtt ggaaggaaag cactagatac tttttctata gtagtttcat
     3001 ttattttgcg gtattctata aggtctttta tagtgatgat ttttaaatta tgcttttctt
     3061 tgaaaatcat taaatcatca actcttgcca ttgtaccatc atctttcatt atttcacaga
     3121 taagaccaat ctctttaaaa cctgcaagtc tagcaagatc tactgaggct tctgtatgtc
     3181 catccctgac aagaactcca ccagtttttg ctattaaagg aaatatgtga ccaggcgttt
     3241 tgaaatcttt acttgtagaa ttttcatcac agaacaattt tacagtttca gctctttcat
     3301 atgcagatat accagttaga gtatctgctc catctatagt aacagtaaag gctgtttgaa
     3361 atgtatctgt attttctcta accataagag gtatattaag acttttaaat tttttttcag
     3421 tggcaggtag acaaattaga cctctaccat atgtagccat aaaatttatt gattcaggag
     3481 tagccatttc agctgccatc aataaatctc cttcattctc tctactttca tcatcaacta
     3541 cgattaccat tttcccattt tttatatctt caatagcttc ttcaatagta ttaaacatgt
     3601 aattcactcc tttattattt ttaaaaacca tttttaaata aaaaatcttt atctatattt
     3661 gatttatggt tactactatt agaatttaat tccttgtagt tattagccat aaaattatta
     3721 acatactttc caattacatc gctttctaaa ttaacaaaat ctccaacatt ctttgtcaag
     3781 agaatagtgt taattttagt atgaggtata atagaaacct taaatatttc atcatctaaa
     3841 tatgatatag ttaaacttac accatcaata gcaacagaac ctttgagtat cattgaagat
     3901 aaaagttttt tattaggtcg tatacttact aaaactgcat tttcatcttt ttcaaatttg
     3961 cagatagttc ctttaccatc aacatgacct gttactatat gaccaccaaa tcttgaagaa
     4021 agactcatag ctctttcaag atttaccttg tcatttgcat ttaataaacc taaatttgtg
     4081 gaacgaattg tctccatcat aacatcggct gtaaattcat tttttccgag gtttgaaaca
     4141 gttagacaaa ctccatttac ggctatacta tctccaagat ttgtgccatc taatatttta
     4201 tttgatagta tggttacttt tccactctta ccattagcag taatttttct aagtattcca
     4261 acttcttcta ctatgccagt aaacatccta acctcctata tgaatgtatt aacaaaaatt
     4321 taatttaaaa catctgattc tataagaata tcgccatcta tcaaagttac attattgatt
     4381 gttaactgtg ttgaatctga caaatgattt attccttctc cagaaacgaa tgtaggtgca
     4441 tctttaccac ctataatctt gggtgataga aataatttga ctttatcaac taacttattt
     4501 ctaaagagac tgtcattgag agtagcacca ccttcaacta gaacagaatc aatgtttaac
     4561 tctcctaatt tatacattac aaattccaaa tctactaagt tgttttttga aggagaaatt
     4621 attgtttcaa cattattttc ttttaacata gataatttta tactttcttt gcaacatgtg
     4681 aaaactatag ttttactggt tttatcttta accaaattac tattaagtgg caactttagg
     4741 tgtgtatcta ttactattct tgtaggatga gacacttttt cttgattgag cctgcaagtt
     4801 agtaaaggat tatcgttcaa aactgtattt atgccaacca ttatactttg gtatttattt
     4861 ctgtatttat gagttagata ccttgatgat tcattagata tccattttga ttctagtgat
     4921 tttgtagcaa ttttaccatc tagacttact gctgatttta caatacaaag aggtcttttg
     4981 ttttttatat gataaaaaaa tgcctcattt aaatctcttg cttcatcttc taatattccc
     5041 acagtaacat caatattgtt atcttttaat ttttttactc cattaccaca aacaagtgga
     5101 tttgggtcta atgtagatat tacaactctc ttaatcttat tttgtataat tttatctaca
     5161 caaggaggcg ttttcccata atgagaacat ggttctaagt ttacataaag agtagagtct
     5221 tttagacttt gtttagcact gtttatagca tttacttcag catgattaga gccaaatttc
     5281 tcatgatatc ctttgcctat tatattacta tctttaacaa ttacacaccc aactaatgga
     5341 tttggattta caaagccttc tccattttta gccaattcaa tagccttttt catataataa
     5401 atatcttttt ctttttgatt cacaatatgt acacctcctg tttaattgga taatttttaa
     5461 acaaaaaacc ctgagaatta actcagggtt tagaataatc tacaataaat gtttaataaa
     5521 agtagaagaa aattgctcta caaaaacact cattaaatat cttcttccat ccagacttta
     5581 ctgtcggctt tggaatttaa ccaaatcaac caagttttac cttggctcgc gggctatacc
     5641 gccgattggg aatttcaccc taccccgaag attaagtatt aaatttatat ttagaatgta
     5701 tcataaatta ttttactttg caaactattt ttttaaaaaa tatatgttaa tatataatat
     5761 agaatgtcta taaactttga aataccacga ttgtgaatat aaaaataaaa atttgaacat
     5821 aatcaggaaa gaagtctaat taatttaaat taggagagta atatatgaat aaaaaacttt
     5881 tagaaatact atcaaaatac tatggatata caagttttag aaaaggtcag gaatctataa
     5941 taaattctat cttaagcgaa aaagatgtgt tagctattat gccaacagga gggggaaaat
     6001 caatatgtta tcaaattcca gctttgattt tagatggaat gacaatagta atttctccac
     6061 ttatatcact tatgaaagac caagtagatg ccttaaagac tatgggaatt agtgctgctt
     6121 ttataaatag ttcattaagc agcaaagaat ttaatgaaat attaaataat attagaaaaa
     6181 ataattataa aatactctat attgctccag agagattaga tgcacaagag tttattgagc
     6241 taataaataa taacaatgta agtcaagttg cgatagatga agcacattgt gtatctcaat
     6301 gggggcatga ttttaggttg agttatagaa ggatttctga ttttataaaa aatttgccta
     6361 aaagacctat agttacagca tttactgcaa cagcttcaga agaggtaaga actgatataa
     6421 taaatttact gtgtttagaa aatccagatt attatataac tggatttgat agagagaatt
     6481 tatcaataaa tatagtaaaa tcatctagta aaaataagta tattttagat tatattcaaa
     6541 atcataaaaa tgagtctgga attatatatg ttgcaactag aaaggaagtt gaaaatatat
     6601 ataatggttt atctaagaga aatatatctg tatcaaaata tcatgcaggt ttatctaaaa
     6661 atgaaagaag taaaaatcaa gaagatttta taaatgataa tgtggatata atggtagcaa
     6721 caaatgcatt tggaatgggt attgataaac ctaatataag atgggttata cattacaata
     6781 tgcctcaaag tatagaaaac tactatcaag aaataggtag agctggtagg gatggagaaa
     6841 aaagtgagtg tgtactttta ttttctccag gagatgtaca tatacaaaaa tatttaattg
     6901 atattggagt tgaaaatcct gaaagaaaat tatttcagca taagaagctt caatacatga
     6961 ttgacttagt ttacagtaat tcatgctata gaaagacaat attgagttat tttggagaaa
     7021 attatataga caattgcaat aattgtagca attgtttagt agagggtgaa atagtagata
     7081 aaactataga tgcacaaaaa gtcatttcat gtgtagctag aatgaaaaga agttatggtg
     7141 ttactactat tgtagatgta cttagaggtt ctaagaataa aaagatttta cagcttggat
     7201 taaatacttt gtctacatat aacattatga gagattattc tagtgaagac ttaaagaatt
     7261 ttgtaaatac attggtttct catggttttt tagatttagt tgagactcta ggcaatggaa
     7321 atagaggtag ttttcctact ataagattaa atgagatgtc tatgaaagtt ttaaaaggtg
     7381 aagtgaaagt agagtttaaa gaaattgtta tgacaaaatc attggaagta gaggatgagt
     7441 tatataatgc tttaagagaa cttagacatt caattgcaag tgaagaaagg atagctccat
     7501 atatggtatt tggagatggt acacttagag ccatgtctag tagttatcca attaataaag
     7561 aagaaatgct agatatctct ggagtaggag aaattaaata tcaaaaatat ggtagagatt
     7621 ttgaagcagt aattaaagaa tatgtcgaaa aaaataatat aaataaaaaa atagatgaaa
     7681 aaaatgtcga tttaaagaac gttaatagtg atttcttaga ggttaataca gataaagttt
     7741 tatatgaaaa actgttagtc attagagaag aatatgcaac aaaggaaaaa ttacctgcat
     7801 atatgatttt agccaataag gctttgaaag aaataagtgg aagatatcca cttgatgaag
     7861 aacaattaaa agatatttct ggcataggtg gagtaaaatt tgaaaaatat ggagctagta
     7921 ttttggcaga ggttaataaa tatgtaaaag aaaataatat taatgttatt tgggagaaaa
     7981 agggcaaaag gaagttaata ttagatggag aaagtagaaa aaataatgaa atagcattag
     8041 atttgctaaa tcaaggaaaa gatatacaaa gtatcagtca agaaatagaa gtttcactgt
     8101 caaccattat tggatatgtg catgactatg taaaggatgg acatagtata tcatttgaat
     8161 taggactaga aaatttttat aatgaagata aaaagaagat gattttagaa gtttgcgaaa
     8221 aagttggcta tgataattta aataacataa aaagaaaact tccagattca ataaagtatg
     8281 aaaatataag agctgtgata cttgattctt atcttgaaaa cttaaaaaaa aatattatag
     8341 cagagtaatt tttaacttaa taaaaaataa aatttgtatt attgtgttga actaataatt
     8401 ttgctgtgtt atactgaatt tgtaaaaata atgaaaaatt agagctaggg gcgctagaat
     8461 tggctagctg agagataaag ccgtaactta caaaccctaa taacctgatc aagataatgc
     8521 ttgcgaaggg aagcttttta atataatttt attatataaa taggcaaatt attcaatgtt
     8581 aggagaaatt tgtctaagtg tatatacgat tataagagtg ctttccaaac gaggaaaagc
     8641 acttttttta ttttcaaaaa ctataacttt aatcttggag gattgtaata tgaactatac
     8701 aacacaaatg gatgctgcta gaaaaggcat aataactaaa gaaatggaaa tcgtttctca
     8761 aaaagaacag gtagatgtaa atgaattaag agaattaata gcaaatggac aagttgttat
     8821 accagctaat aaaaatcata aatctttaag tgcagaaggt gtaggtaaaa atttaagaac
     8881 aaaaataaat gtaaatctag gaatttcaag agattgtaag gatatagaaa aagaacttga
     8941 aaaagttaga gtagcaatag acatgaaagc tgaagctata atggatttaa gtaattatgg
     9001 caaaactaga gaatttagag aaaaggttgt tgaaatgtca cctgcaatga taggttcagt
     9061 acctatgtat gatgcagtag gatatttgga aaaagaatta aaagatataa cagaagaaga
     9121 gtttttaaat gtaataagac aacatgctat tgatggagta gactttatta ctatacatgc
     9181 aggtcttaca agaagtgttt gccaaaaaat aaaaaatcat gagagattga ctcatatagt
     9241 atctcgtgga ggttctttat tgtttgcatg gatggaatta aataataagg aaaatcctat
     9301 ttatactaat tttgataaaa tattggatat atgtgaagaa tatgatgtta cattgagttt
     9361 aggagatgct tgtagaccag gttgtataaa agattctact gatggtgttc aaattcaaga
     9421 acttgtagta ttaggtgaac ttactaaaag agcatgggaa agaaatgtac aagtaatgat
     9481 agaaggtcct ggacacatgg ctattgatga aatagaagca aatgtagtat tagaaaagag
     9541 attatgccat ggagcacctt tttatgttct tggaccattg gttacagata tagcaccagg
     9601 ttatgaccat ataacaagtg caataggagg agctttagca tgtgctaaag gagtagattt
     9661 tttatgttat gtaactccag cagaacattt aagattgcct aatttagatg atatgaaaga
     9721 gggtataata gctgcaaaga tagctgctca tgcaggagat atagctaaaa atgttaaagg
     9781 tgctcgtgaa tgggataata agatgagtaa agctagagct gatttagact ggtgtgagat
     9841 gtttagactt gcaatagacc ctgaaaaagc taagagatac agagatgaat caactcctac
     9901 tcatgaggat agttgtacta tgtgtggaaa aatgtgctca atgagaacag ttaagaaaat
     9961 attaaacaat gaggaactta atctaatata atttttggct agtatgactg gaataaaaag
    10021 aagctgaaaa gaggaggtga tttagtgaag gttaatggga aggaaattga atttgaaaaa
    10081 gatttgactg ttatagattt attaaataaa tataatttaa aaagtgatag agttgtagtt
    10141 gaagtgaatt tagagataat tgaagaatct aactacaata catatgtatt aaaagacgag
    10201 gacattgtag agcttattag ctttattgga ggtggttaaa ataaaaatat ttgtaaatga
    10261 attattaaca gatgttgagg aaaatacaac tgcttataaa gttagagata gctataacaa
    10321 taaatgtgat gtattggtgt taaatggata tccaattaaa acagatatgc ccctttgtga
    10381 aaatgataaa ttaacactta tacaaaaagg agttaagcca tcacttgatg aattggaaag
    10441 cttgttgatt gctagacata ctccaaatat acataataaa ttaaaaaaag ggaaagttgc
    10501 tatattggga ttggggggac ttggttccaa tatagctatc tctttagcta gaataggagt
    10561 gggagaactt ttacttatag attatgatgt tgtagaacca tctaatttaa atagacagca
    10621 gtattttata gatgatatag gaaaactaaa aactgatgcc atgatagaaa atataaaaaa
    10681 aataaatcca tttataaaat taaataaacg agatattttt ttaaacaaga acaatatgga
    10741 tactattaag gattcagatt taataattga ggcctttgat gatgcttcat gtaaagcaca
    10801 ggtatgtaat tatgtattaa taaatttaaa agataaatat ttaatagcat catctggtat
    10861 ggcaggttac tatgattcaa atataataac tactaagaag ataaaagaca ggttttatat
    10921 atgtggggat tttgtgaatg aagctaaatt tggtgaaggg cttatggctc caagggttgc
    10981 catctgcgca aatcatatgg caaatttggc aacgcaaata cttatagata tgtaaatatt
    11041 aaaattagat ataaaaaaga ttgaatatta aaaaaattta acgtggaggg aaataatatg
    11101 gataaattgg tacttggtgg acatgaattt aatagcagat tattggttgg aacaggtaaa
    11161 tatggttcaa ataatatatt gcctgaggta ataaaagaaa gtggaagtga aataataaca
    11221 atggcactta gaagagtgga tttagacaat aaacaagaaa acatattaac gtatattcca
    11281 aaagagatga caatacttcc aaatacatca ggagctacta atgcagaaga agctgtaaga
    11341 atagctagaa tatctagaaa aatgggatgt ggagatttta taaaaataga agtaatatca
    11401 gatactagat atttacttcc tgataatgaa gaaactataa aagctacaaa gatacttgct
    11461 aatgaggggt ttatagttct tccatatatg acaccagacc tttatgctgg aagaagactt
    11521 atagaagcta atgcagcggc agttatgcca cttggagctc caattggttc aaatagaggt
    11581 cttcaaatga aagaaatgat aagaataatg atagatgagt tggatatacc aataatagta
    11641 gatgcaggta ttggaaaacc atctcaagct atggaggcta tggaaatggg agctgatgca
    11701 gtacttgtca acactgctat agcttcagca ggagaccctg tacaaatggc tagagcattt
    11761 aaattagctg tagaaggtgg aagagaagca tatattgcaa aaacaggaaa tgtgtcagaa
    11821 tttgcaaatg catcttctcc tttaacaggt tttttaggca atttatagaa agtggtgatt
    11881 ggtgatgagt ttttatgatg taatagaaaa atatagggat tttgattttg atggatattt
    11941 aaataatgtt actgataatg atgttttaag aagtttatca aaagacaagc ttgaagattt
    12001 tgatatatta aatttgcttt ctaaaactgc agtaaaacat ttagaagata tggcacaaaa
    12061 agcacataaa ttaagtgttc aatactttgg taaaacagta tgtttatata caccaatgta
    12121 tatagcaaat tattgtgtta atcaatgtgt ttattgtagc tataatataa agagtggaat
    12181 aaaaagaaaa aaattaacta tggatgaaat tagagaagag ggagaagcaa tttcaaaaga
    12241 aggtttcaaa catctacttg ttttgactgg agaaagtagt tttcactcaa gtgtagaata
    12301 tataggtgag gctatagaaa tattaagaga gaaatttccc tctataggta tagaagttta
    12361 tccaatggaa gtagaagaat ataagtacat tgtagataaa ggtgttgaag gattaacagt
    12421 atatcaagaa acttatgacg aggaaatata taagagagta catataaaag gcccaaaatc
    12481 aaattataaa tttagattag atgctcctga aagaggggca aaagcaggta tgaggacttt
    12541 atcaataggt gcacttttag ggctaaatga ttttagaaaa gaaacttttt ttacaatatt
    12601 gcatgggaaa tacttaaaaa cgaaatatcc tcatattgag ctttcatatt caacaccaag
    12661 aatgagacct tttaaagggt gttttgagga attggtagat ataagtgata ctgatttagt
    12721 tcaagctatg gtatgtatga gattatttga ccctcatgca gctataaata tatccactag
    12781 agaaaattta gaaatgagaa gtcatataat acctttagga gtaactaaat tgagcgcagg
    12841 tgtatctact gatgtaggag gtcattctca agatgaacat gatactgctc aatttaagat
    12901 aaatgatgaa agtactgtta aagatgtgga gaaaatgcta aactcaattg gttatcagca
    12961 tgtgtttaaa gattgggaaa gattttaaat gtatctgata acaaacagaa aattatgtag
    13021 tgaggaacga tatttagaag ttattaaaga gtctatattg agtggtgtag aaaatataat
    13081 aataagagaa aaggatttgg aatatcaaga gctaagaaaa ttatatatga aaataaaaac
    13141 taaaatcaat tgtatagatt ttcaagagca aatatcagat gaaagtttga aaactaatat
    13201 aaatcaaaaa gagtgtagaa ataaattcaa ggttaatttt ataataaata gtaacattga
    13261 attttttgaa aaagtggatt gtcaaggtat ccatcttcct tttaaattat tcttgaattt
    13321 aattgaaaat aagtataatt ttaatgaaaa taaaatacta ggattatctt tacataaagt
    13381 agaggaagta gattatttag aaaaattaat aagaaatcaa aatataaaaa tagattacat
    13441 aacattatca catatatatg aaactaaatg taaagaagga ttaaatccaa aaggaattga
    13501 gcttttaaaa gaagctaaaa agattactga tattaaaata attgcacttg ggggaatttt
    13561 accatctaat gtcaaagaaa cattaaaata ctgtgatgat tttgctataa tgtcaactat
    13621 aatgaggtct aaagatatta aaaaaaccat atcaaattat aatgaaaagt tgaattagta
    13681 aatatagtat attgaatttt taacttaaat aaaaataaaa aagttatctt ttaaatttta
    13741 aaaggtagct tttttatttt atatctttgc taataaaaaa ttgtaaaaag ggaaaacttt
    13801 agtcagagag attaaacaat atcctagaaa gatttaaaat ttagtaaagt atggaggaca
    13861 ttataatgac tgacagtaaa aagaaacgat ttattatacc acacactttt acaataatat
    13921 ttttactaat agtcttaatg gcaatattga cttggatagt accaagtggt gaatttagta
    13981 gagaagatgt agaaggtaga atggtagttg taccagggac ttatcaaagt gtagaaagta
    14041 atcctcaagg atttgcagat gtttttaaag caccaataga aggctttatc gattcagctg
    14101 aagttgtagg ttttgtttta atagttggag gtgcttttgg tattgtaaat aggactggag
    14161 ctatagaagc aggaatagct tcggttatct ctaagtttaa gggaaaagaa cttcttataa
    14221 ttccaatatc aatgatttta tttggacttg gaggtacaac atttgggatg gcagaagaga
    14281 cattaccatt ttatatgata tttgttccac tcatgacatc cttgggatat gattctctaa
    14341 cagcaatagc aattgtattt ataggagcag cagcaggagc cgccgcttca acaataaatc
    14401 cattttcagt tggtattgca caggcactag ctcaacttgc tcctggttca ggagtaactt
    14461 acagagtagt tatttttata gcatatatac taataagtat agcatttgtt atgtactatg
    14521 ctaagaaggt aaaggaaaat cctgaaagtt caatagtata tgaaatagat aaaaataata
    14581 aatcaatact taatcaaact tcaacagaaa taaaagaatt tacttttaaa gaagtatctg
    14641 ttcttgctat atttggaata gggatggcaa taatgatttg gggtgtttta agtcaaggat
    14701 ggtacattcc agaaatatca atgtgttttg ctgcaatagg tgtgctttct ggattggttg
    14761 gtagattatc tcaaattgaa atctcagaaa gttttataga tggagcaaaa gatttagcat
    14821 ctgcagctct tgctatagct ttggctcgtg gaatcgtaat aattgctcaa aatggattta
    14881 taatagatac tatattaaat tccgcagcag cctttctagg tgggcttcca aaggttatat
    14941 ttgtatattt atcatttttc ttggaagctg cattggcatt tttaattcca tcatcttcag
    15001 gtcttgcttc acttacagta cctgtacttg ctcctcttgg tgatttggtt aatatatcgg
    15061 ctcaagtgat agtaaccgct tatcaatttg gtgtgggtct tacaaacttt ataactccaa
    15121 cttcaggagt actgatggga gcacttgcag tagcccatat tccattttca aaatgggtaa
    15181 gatttataat gcctatcttg ttgattttga cagttgtatc tctagtcttt ttaacaatag
    15241 gtatttatat agggttttaa ttaagtgtag ttttatttaa gatatttagt aatggtataa
    15301 aatgataata tgttttcaat aaattgccac taatttaatt agtggtaatt tgttttttgt
    15361 atttaaaaat aaatgtattt acttgtattt tgaattaata tctacttaga cattgtttta
    15421 attgttatat tttcatttaa ttaagcattg atttatcgtt ttttatattt catataacaa
    15481 tgcaaaaaat aatttttata tagtaaatga caaaagttta caataaatgt atattttctt
    15541 actcattcct taaaattact catttagttt aataactctc atttcatatg taaagttggt
    15601 aaaaaaatta aaattaaaag taaaaaacta aataaattaa tgttaatttg aaatatatat
    15661 gaaggttttt ggagaatact tacttatgat aggaaaaaat gttaaaataa taatgtaatc
    15721 aaatataaag gactgaaata attaacagtt attaaatatt aggagtgtaa aaatttatgg
    15781 gattaaaaga atttgatttt attgaagagt ctattgatat gttgaggaca atgtcaccaa
    15841 cattagaaac tatatcagat gaaatagaag agtattttga aaatatcttg gatgaaaaga
    15901 atcaagaata tataaatgta acctctagaa taaaatcaga atcaagttta agagaaaaga
    15961 taattagaaa tagatattta aaaaaatatg gagaagcaag taatcttatt cataatgttt
    16021 ctgacttaat aggcctaaga attgagtgta gatttattga ggatgaaaac aaaatatata
    16081 gacttttgag aagatatttt aataaaacag atgacaaaat aaactattat aataaagaga
    16141 ataagaatat taaattaaaa ctatctgaga ggcaacccaa taagcaaaaa aatggatttg
    16201 aaatatataa aatagatgga gtttttgcgt atttagatag agaagtaaaa tttgaacttc
    16261 aaattaaatc tcttgtaaat gtgttttgga gtgaaataga acataaaata atttataaaa
    16321 acaatacata tttacttgct gataaattta taaaggatat gatggactct ataaagaata
    16381 atcttactat gatagataat cagcttttaa gtatttataa aaactttcat tcagggaagt
    16441 cttttaatat gaaagtaagt aaaaaagaaa ttgaaaaatt atttgcgaaa ctagtctatg
    16501 acgctttttc tgaaaagatg aataaaagta taggttttgt tgtagatttt aaaaaaccat
    16561 gtgaaactat attgaactat tcttttaata aacaagatat aagtgatgaa gttttaggta
    16621 attttatgct tgatgagttt gcaagattaa atgaaattgt aaacaaggat atagatttta
    16681 atgagcaaat agaatttgaa agagaaccaa catttgatga taagttttgt aaagacctag
    16741 gaaatcattt tagaagtaga ttaaacacag aatttccatg gaacctattt tttagaatat
    16801 tatttgaaat agagccatat aacaatacca aagactttga aaactttgta gagtttataa
    16861 aagaaaatgt gctactagaa gaaaataggg agcaattatt atgccaattt gaagaagata
    16921 gcaagcttat aattgaagat atatatgatt gtatatttaa tagtataagt gagattgata
    16981 gtgttgaaat tttatataac tataatcttg aaaaaataaa ctttacatca agtgaaatca
    17041 taaattgtat atgtagagaa tatgagtgtt atggtgaata cttagaagaa aaagaaaagc
    17101 ttatgaatac atttaaagaa aagcttattc aaatctttga gtaataggtc aatgctgaag
    17161 tggcgctaat gcgccatttt tcaaatatat atgaattaag taaaattatt ttggaggagg
    17221 cgatttgtat agagaaaaca ggtgtaattt tggcaggggg aaaaaattct agaatgggta
    17281 gagataaagc ctttttagag ttacatgata agctttttat tgaaattgca atagaagcat
    17341 ttaaaaactt tgatgagttg ataataatat ctaataatga agaattatat tctaaatacg
    17401 atattaaagt ttataatgat atagtaaaag atgttggtcc aattggagga atatatactg
    17461 ctcttgaata tgcaaagtat gatatagtta caattgcatg tgatatgcca tatctaaata
    17521 atcaaatagt cgaaagaata gctaataaaa tgaatgataa aagtgtgatt tcagtgacaa
    17581 atggaaagtt acaaccattg tgttctggat ataaaaagag tataataaat aaagtatctt
    17641 tatgtataag ggaaaatgat ttaaagctca gaagctttat agataaaata gataaaagtt
    17701 atatacactt tgatgaagaa gatttatttt taaatgtaaa cactgttgat gagtatgaaa
    17761 aattaactaa agtttaatta gctatggttg taaaatagag taggatttat atggaggaga
    17821 gtttatgaat ttacttaaat gcgattcttg ggcagtaata ttaaataata gcgataaaga
    17881 aagtaaagca tataaaatat tagatgaact taaaaggaat atgtacaaag ttgttgctat
    17941 agatgaagag aaaaaaacta ttgaaggaat agatgtgtat gaatgtttaa aagatgttcc
    18001 acacaatatt gatgttgtag ctattattga taaacaatct aagatggatg tgattttaga
    18061 agaagtagag cttttggata tacaaaatat gtggtttgaa aaaggaagct ttagtgaaat
    18121 gatgattaaa aagactaaag atttaaaatt aaatatagaa tataatttaa gtttatatga
    18181 tgagttgact agataaaatt atatttctta ataataaaaa tataattagt taataaaaca
    18241 tattatttta tagtatagat tggttaataa aagtacagat tggttaatga aacattaaat
    18301 tacaatattt gttaaaaaaa ttgtgagtta catgatataa tgtattaaat aggatactaa
    18361 ggagttgata tattatgtta atagtaacta cagaaaaagt agaaggtaaa aagatatcaa
    18421 aggttttagg attagtgaga ggaagtacaa taagagcaaa acatgttgga aaagatatag
    18481 gagcaagttt taagaatctt gttggaggag aacttactgg atataatgaa atgctcactg
    18541 aagcaagaca aattgccata ggtagaatgg ttgaagatgc agaagctaaa ggtgcaaacg
    18601 cagtaatagc atttaggctg tcttcagctt cagttatgca aggggcagca gaaatgcttg
    18661 cttatggaac agcagttgtt ttagaagatg ataatagtat tcttgaaaaa taaaatataa
    18721 atagttaaaa agaggcatct tttaaaaatt ttatggatgc ctttttttat ttgaaaaaac
    18781 taatttgaga agaaatttta actattatga caataaaatt agggtgatat tatataaata
    18841 agtaaaatta tattatataa tgtatggtat agactttaaa aattttattt gtagagaaaa
    18901 atatggacaa tgttataata attatagaaa ttaaaagtac ttacattcat tatgtatgtg
    18961 acatgtataa ttagttttat atttaataca gttttgaagt aatatcttca ttttgagaac
    19021 gttggaataa taaaaaatgt atgtattata ggtgatataa ataaaaaata aatataatat
    19081 gttatattgc tgatagaaaa gagaataaaa gaaaagaggt tttattaaaa gagattttta
    19141 tttataggac ttaatcaatg tatagagggg tgagaacata tgtttaatgt tgcaattata
    19201 acacttagtg ataaaggata tgaaggaaaa agagaagata taacaggaaa aaagttaact
    19261 gaatttgttg aaaatacagg agcttataaa gttactgagt atgtacttat aaaagatgat
    19321 aaggaaatgc taaaggaaaa tattataaga ctttgtaata gtaataaaat agatttaatt
    19381 cttacaaatg gaggtactgg tttttcaaaa agagatataa ccccagaagc aactaaggaa
    19441 gtgttggaaa aagaaatacc aggtctgagc gaatatatga gaatgaaatc cacagaaatt
    19501 actaaaaagg ccatactaag taggggtgtg agtggaataa gaaataattc tataataata
    19561 aatttacctg gaagtcctaa aggtgcagtt gaaaatctaa gttttataat tgatgtttta
    19621 gaccatggca tagaagtttt aagaggagaa gctacagaat gtgccactaa aaaaagtgaa
    19681 tagtatataa tctagataga taaaaaatag acaaagaggt agataaagta tgattgataa
    19741 gtatggaaga aaaatagact accttcgtat ttcacttaca gataagtgta atttaaggtg
    19801 tgtctattgt atgccaccag atgtaaaatt tgataaaaat tatataaatg aaaatctaag
    19861 ctttgaagac tacaagttta ttataaaggc tatggctgaa caaggtataa caaaaattag
    19921 atttactgga ggagaacctc ttttatatcc taaattaaat gagcttataa aatttacaaa
    19981 agaagaatgt ggaataaata acataggaat gactactaat gctattgggc tttctgatag
    20041 aatttttgag cttgaaaaat gtggcttaaa taaagttaat ataagtttag attctttgaa
    20101 ggaatataag tataaatccg taacaagagg aggaaactta aaagatgtct taaaatcgat
    20161 tgaatcttgt ttaaacttag gtataaaagt aaagttaaat tgcgttgcta taagtgggtt
    20221 taatgatgat gagcttaaag attttatgtt tttaacagtt aaatcaccaa ttgatgtaag
    20281 atttatagag cttatgccat taggtgaggc taatagagtt tataagaagg gttattttaa
    20341 tgtaaaagaa atgattgaaa aaatatatgg tttatataaa gtcaaaaatg atgaaaaaag
    20401 tacagcagaa tattatatgt ttaaaggagc taaaggaaga ataggaatta taactccatt
    20461 aagctgttca ttttgtaaca cttgtaatcg tattagactt acttctagtg gtgcaataaa
    20521 attatgtcta cattcaaaag aagaaataga tataaaacca tttttacata aaccattgtt
    20581 atttagagaa tctatgaaag atataataaa acaaaaacca gaaaaacatc atttaataga
    20641 aaataaatgt agtgatacaa ataggcgtat gtatgaaatt ggaggataag taatgttaac
    20701 acatataaat gaaaaagggt atgccaagat ggtggacata agtgaaaaag atgatactaa
    20761 aagaacggcc atagctacag ctacaattac tcttagtaag gaagcattag aaaaagtaaa
    20821 aaatggtcag ataaaaaaag gagacgtatt gtctgtagct caagttgcag gtataatggg
    20881 agctaaaaat acatcttcaa acataccaat gtgccatcag attaaattag ttggatgtga
    20941 tttagaattt gatgtagatg attatatgtc tgctattaag atatacgcaa cctgtaaatc
    21001 tcttgggaaa actggagtag aaatggaagc tttaaatgca tgttctttag cagcacttac
    21061 aatttatgat atgtgtaaag cagttgataa aaaaatggtt ataagtaata tccatcttgt
    21121 ggagaagact ggtggaaaat caggagattt taagttcgag taaattaata atatattggg
    21181 ttaaaatttg gaggaaatat ggcgaaggta gtgtcaataa atataagtga gaaaaagggt
    21241 gtaattaaag ttcctgtacc atgtgcagag ctaaaaataa atcatgggat agttggagat
    21301 gcacatgcag gaaactggca tcgtcagata agcttacttg gaaaagaaag catagataaa
    21361 atgaaaatga aaggctttga ccaattaaaa tatggagatt ttgctgaaaa tgtaactaca
    21421 gaagggatag aagttttttc cctgcctgtt ggtacaaagt taagaatagg gcaatgtgaa
    21481 gttgaagtaa ctcaaatagg gaaaaaatgt cacaatggat gtgaaattaa gaaattgaca
    21541 ggtgactgtg tgatgccacg agaaggaatt tttgtaaagg ttctaaaaga aggaattata
    21601 aatgtgaatg attcaataga tgtaatctaa tgaagtcact attaaaatat aattataagt
    21661 aaatactatt aagatttaaa tatatatttt aagagagaat taatttaaat aaaatatttt
    21721 agttataaat tggaatattg gttatataaa gctatgaatg taaaatcata gctttttgtt
    21781 tttgaat
//
LOCUS       DACTZW010000074        21179 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.074, whole genome shotgun sequence.
ACCESSION   DACTZW010000074 DACTZW010000000
VERSION     DACTZW010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21179)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21179)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21179
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.074"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            709..1398
                     /locus_tag="JAM15_14165"
     CDS             709..1398
                     /locus_tag="JAM15_14165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6799402.1"
                     /translation="MDILLVEDDKNIREMVYDFLISENYFVKTAVDGNTAIEIFKNYS
                     FDIILLDLMLPKSSGFEVLKYIRSVSVVPVIITTAKDSDTDKMLGLNLGADDYITKPF
                     SIVELLARIKANIRRATVYSSSRNSEDMVIQYKDLIINISKYVVSKNGIDLNLTHTEF
                     EIVKLLATNQGRAFSKEQLYNTIWKEPYYGNENVLNTHINRLRNKLSDGIEKNNYIKT
                     LWGIGYKMEEE"
     gene            1398..2315
                     /locus_tag="JAM15_14170"
     CDS             1398..2315
                     /locus_tag="JAM15_14170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAT6799403.1"
                     /translation="MELFLVVISIVLFAFYLKERNKSKKMESDYKYINSRLRDITNDD
                     EINYILVPSDISIVKETAVDINKLLEKFYSRQINYNRSEKAILQIFTNISHDLRTPIT
                     VLKGYIEMLYLQSQKEELSSSMRATLEKMQTNSNELVNSINNLFNMAKIQSGDMILNL
                     QKSNLTQLCHEIILEFYDLLDKENFNVEVNIEDRPIYANVDTEALQRILKNLIDNAIK
                     YGSDGRFLGISLYEKEKHVFIDIEDKGSGISETEKEHIFTRAYTADRKKGNGLGLAIS
                     QGLANSMGGSIYVNSRPNVKTVFTVKLKS"
     gene            2388..3314
                     /locus_tag="JAM15_14175"
     CDS             2388..3314
                     /locus_tag="JAM15_14175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6799404.1"
                     /translation="MNYIIETHQLKKIYKDKAVVNAVNIHVKKGEIYGFVGPNGAGKS
                     TVMKMLLNLVNPNSGEIVMFGKKVAETDFEILKKIGTIIENPYLYENLTAKQNLDLHC
                     EYMGYYNKEHISEVLECVGLSKQSNKKVSKYSLGMKQRLAIARAILTKPELLILDEPI
                     NALDPEGIREMRELFRKLNTDYGITIFISSHILSEVEQIADTIGIIQDGKLIKEISMS
                     DIHKYQTDYVEVDVDNVELAGYLLEKEFGIKDFKITSESCIEIYDLRKDVKEISKIFI
                     QNQIGINSIGRKQSSLEDYFFQTTGTGGKETL"
     gene            3311..3991
                     /locus_tag="JAM15_14180"
     CDS             3311..3991
                     /locus_tag="JAM15_14180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAT6799405.1"
                     /translation="MIHLMKLELKKVGLKRYFLFSILGIFLCMFFVFTGLNDKSTSIY
                     DYDVTFRTISLFFCFYYIILFAVLNVAYIINEYTNKTILILFFYPLDRKKLILSKLLL
                     ITTLMISSMIVGYICCFTFVVVLDKYFNLVIGDFHISILSYWIPGAIKSIIIFCSLGI
                     WTFVVGMIRKSIPVTLVSSIIFINLRQFILAGTNTTQDSLISVFIIVGITVIGIYYIL
                     NHKVTEID"
     gene            4089..4424
                     /locus_tag="JAM15_14185"
                     /pseudo
     CDS             4089..4424
                     /locus_tag="JAM15_14185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427885.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
     gene            5288..5938
                     /locus_tag="JAM15_14190"
     CDS             5288..5938
                     /locus_tag="JAM15_14190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAT6799406.1"
                     /translation="MKVKSNLDEILYHKIIESLIRGEYSVGQKILLNDLCEKFEVSRT
                     PVVQAVKMLNKDGVLTIMTNGKVYVPEYEYDMVKQVCETRTLIETYALEKMMQEEEEV
                     FQQKLDVIKRYSDKCEEYYRQEKSVELALADLELHKAIVEGANNEILNDVYVGIQGRF
                     IVVNYLIRPLKNRNYEGTVQDHFEILKFIEDRDTKKAVDKLRNHIQGTIKRFCEDE"
     gene            6282..8348
                     /locus_tag="JAM15_14195"
     CDS             6282..8348
                     /locus_tag="JAM15_14195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HAT6799407.1"
                     /translation="MKEVVGSLKKITKERIENTMKKLFTSETFLEYQFISDCQISPDG
                     GYTAFIVKKADIKENGYTSQVYILNNKTGELKQITSINSVGAYVWEDENTILFPALRN
                     EKVKEAVKNGKQCMSYYALSLNGGEAEELFRLPIKGGKLNHIGKGLYAVIDSYDNDRP
                     IVEGLSEEEQQKKINAYNKRHYEHFKEIPYAVNGEGYISRKRKRLYIYDSNINELKAI
                     TAPMFNVVGMKISDGKILYIGQEFKDVKGLKNGVYVFDTNTNTNICILEKDKYIIKGF
                     ELYQNQVILNLTDALSYGNGENGDFYTIDIDTKEMKLLSGHQHHCIGNTVTSDVKMGA
                     GQTTKLDGEYIYYTSTVDMDCIIERIHIPTGKQEKVTQTGSVDFIDVKDGNIVCVGCL
                     GNGLPEVYTVENGTLCKKTHLNDHILEEYKISVPEYIESKGSSKWEIQGYVYKPVDYE
                     VGKKYPAVLAIHGGPRLTYGPYFMHEIQVFTSAGYFVFFCNPRGSEGRGNAFADIRKQ
                     FGDIDYIDFMEFTDTVLEKYTDIDKTKLAVEGGSYGGFMTNWIIGHTNRFAVACAQRS
                     IANWSGMEGTTDIGYYFCKGQTGASHMENHELQWKQSPLAYADKCVTPTLFLHGEKDY
                     RCYMQEAFQMFSALKIHGCPTKLCLFEGENHELSRSGRPKQRLQRLVEMLDWFSVYIK
                     KDNIGQ"
     gene            8365..10320
                     /locus_tag="JAM15_14200"
     CDS             8365..10320
                     /locus_tag="JAM15_14200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HAT6799408.1"
                     /translation="MEKIKIESSDIFEYIFPHDISCSPDGKHIAYIISNINEEKDCYE
                     HDLYVMDIKTEKQIHMTQTKDVTSFSWISNTELLFTSKRNKPKAGTTDFYTISIEGGE
                     AKEAFSIPKACSVPVSLGNKLWLLTTKNPTDSKKSEPDRAVEGVDYWTFTDKPFIRDG
                     ENFSQRRRVTLELYQEGENITKAITPKFCEVAGIDVSSDKNRILYTGQIYEDCATPFS
                     GLWEYHIDSGETKELVPQGKYQISLAKYIGKDKVMLQASTLERSITQNHDIFILDLST
                     SEINMIASPDGMYATLLDVDAVYGGGRSNKVIGDKFIGARICRTMTEFNEFDTKTGNI
                     RIITKVDAFTSFDIYDNTMYTVMLKDYELAEIYSIDMTTGTMKKMTAFSKPYLDTHKV
                     SLPEKLTFVAKNKEEVDGFVIPPIDAKEGEKYPAVLFIHGGPKWAYGYMFTHLKQCVT
                     SKGMYVIYCNPHGGDGYGEKFLEMVERWGYVDYEHLMEFVDTCIEKYPGIDADRLGVA
                     GGSYGGYMTNWIIGHTDRFKAAVSQRGISNLITASLIIDFGDRIMKQTCGDKTPWNHE
                     EVLWNHSPIKYVKNVKTPTLFLHSDRDYRCFMGDTFQMFTALKQLGVDTEMYLFHGDT
                     HGLSRNGRPSNRIARANAIVDWFERYL"
     gene            10336..11526
                     /locus_tag="JAM15_14205"
     CDS             10336..11526
                     /locus_tag="JAM15_14205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HAT6799409.1"
                     /translation="MSDMLLWFSVVLVLFAIGDLIASKTKAKVSAVFVTLLLFLILFV
                     TKAIPADIIEKAGMTAAASWSVPMIMFSMGTMLNVKQFIDEWRTVLTAWLGIVAVIVC
                     VSLCIPLFGKSTVLTSIPVINGALPATTIMTQAALEKGLTLAAATATVVFAIQKFIGT
                     PIASRAALQEANRLLVEYHEAKSKDIDLANVDTDKKEAENTGTKVKQAFCEKYDKYYS
                     TNVCIFFIALFSYLGYELSEIIHVNYSIVCLVVGVIVTRIGIVPKDILEKGKIKGFIN
                     MVVFAAVIPSLAKVSLTDLISLFVPIVGMFAASIIGIFLMMKVLPGWKIIGSKPLAFG
                     VGFCQMLGFPTTYLISNEVCNAVGETEEERAYLMSKIMPKLVVGGMACMISIVVAGLM
                     VPML"
     gene            12660..13034
                     /locus_tag="JAM15_14210"
     CDS             12660..13034
                     /locus_tag="JAM15_14210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAT6799410.1"
                     /translation="MKVLISNTSDKPLYQQIKEQIKEAIFTEELKEGDAMPSIRNFAN
                     DLKVSILTIRRVYEELENEGFLTRQVGIGTFISTGNLEILRDSKRRIVEQKMADMIKD
                     AKALGITQIELQEMMDILYEED"
     gene            13036..13893
                     /locus_tag="JAM15_14215"
     CDS             13036..13893
                     /locus_tag="JAM15_14215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6799411.1"
                     /translation="MENILEVYNLNKTYTNFSLSNISFVLPEDCITGFIGVNGAGKTT
                     TIRSILDVVKRDSGKIKIFGKDFDGNEKELKNRIGVVFDDSYFYEELSMSEMKSIIAP
                     SYDNWCEEDYQQNMKRFNLNPKQKIDTLSKGMKMKFALALALSHKAEFLIMDEPTSGL
                     DPLIRSQILDILTEYMKKCGRGVFFSTHITSDLDKIADMIVMIDNGRIILEREKDTLL
                     DEHRKVKGDIQFLNDEIKKLFLNLETTGYGFVGITSKINEVQKNMPDILIERPTIEDI
                     MLAYIERRE"
     gene            13896..14534
                     /locus_tag="JAM15_14220"
     CDS             13896..14534
                     /locus_tag="JAM15_14220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HAT6799412.1"
                     /translation="MLIHLVKKDILIVKKYVLLILFIAIGIPLFILWRLPPFAQILGF
                     VLSIIFSEFMLCQYLLLKESQYSKASVLLCSTPYPRRGLVQSKYVLFAMVFIYCTLVY
                     WIENLLIPQIGTFDLTYILIVLLISSIIYGVYMPIQYKLGYETTKFFFVMIIMASSFV
                     LPLTIAHSNFEIPFIYQYPSMIVNIVLFLLSLIILLASMFISIKIFSNKELV"
     gene            15544..16278
                     /locus_tag="JAM15_14225"
     CDS             15544..16278
                     /locus_tag="JAM15_14225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAT6799413.1"
                     /translation="MNLAKGLDVLKISSNVFGEDKVMYIPVIYTEDDATLIDTGLPGQ
                     GDLIIDALNKSNTSFDRLKNIIITHHDIDHIGNINYLREKSKNNIKVYAYKSEVSYIT
                     GEETPFKLYMLEQMVAKIDDKMLSMLNVMRLGFKSSYTKVDVSLDNHEKLNLGEEIEV
                     IHTGGHTRGHICLYLKESKVLIAGDLLQVENGELTPVDVMHSNKQELKDAIKNISNYD
                     IETIVFSHGGLYQRDIIGTLKNLIIE"
     gene            17457..18713
                     /locus_tag="JAM15_14230"
     CDS             17457..18713
                     /locus_tag="JAM15_14230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel protein"
                     /protein_id="HAT6799414.1"
                     /translation="MIEKFKTLIWIKMIIRIKSVYKTYGGLFLLGLIGIPVGAIIGLI
                     DTIFGTVLLKVTDIRETYPMYLIPFLAVVGVVIAYCYFKFGGKSSKGMNLIFEVGHGE
                     EEIIPLRLVPFIISGTWLTHLFGGSAGREGVAVQIGATFSHWLGKRLPIKNDSSIFLV
                     TGMAAGFAGLFETPIAAILFAMEVLVAGSLEYQSLFPAFTASFTASAVSKALGLEKFS
                     FALSSKVVFDLSIFWKLIALGIVFGMVGGAFAWCLKLSKRKIGNRLKNPMIRIAVIGV
                     CLSVLFLLFYKGRYSGLGTNLIQNSFYGGEIYSFDWLLKFILTILTLSAGFQGGEVTP
                     LFSIGASLGVLLAGFFNLPIELVAALGYASVFGSATNTFFAPVFIGAEVFGYSYLPYF
                     FVVCAISYIFNMDKSIYSLQKISTKQ"
     gene            18776..19969
                     /locus_tag="JAM15_14235"
                     /pseudo
     CDS             18776..19969
                     /locus_tag="JAM15_14235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895690.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
     gene            20176..20556
                     /locus_tag="JAM15_14240"
     CDS             20176..20556
                     /locus_tag="JAM15_14240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HAT6799415.1"
                     /translation="MYLKKLSKLELVIMKFIWNLDIKTNSYEIIDYMKEEHNLPEKVA
                     LKTLSKLSKKRFLYVQETGKCMYYTVAIKEKTYLEFISRSVQNLLKNNFIRNLLVSFH
                     EEELTEEKIKSLENWVVNWEEAYI"
BASE COUNT         7914 a         2284 c         3603 g         7378 t
ORIGIN      
        1 tagcatgatt atggaagttg taggagtact atttatagct attggattaa tcttgacatt
       61 cattgaaata aaaggaaatt tcccttcttt ttatggtttt ggtcaaaatt ctatagggaa
      121 aaatgctgta ggtattatag cagcaggaat tgctttaatt ttctttagaa atggcataga
      181 tagcatagat tctatagcta cttatggtgt atttttagca atagaacttg ttgtaatagt
      241 tgcatatttc ttaataagaa aaaaatttac taaagaagat aaacatttaa gaactaatta
      301 actaaattat ctactataaa attggaaaat taaaaacaaa taaaagtttg tttttaatta
      361 tttaaaatcc aaatttgatt atttttaaag aaactatatt ctgtataaaa ctagaatgtg
      421 gtttcttttt tatgtataaa atatttttta gcaaaagtta aaaggtgttt tataatataa
      481 aatagttaat tgtagatgtt aataaaagaa aattatgtat atttcagata aagataagag
      541 agtatactat attttaatta ttttttcaat aaagcttatt gaaaagaact ttaacttaga
      601 agcgtatcac caaattgcag atacaatatc ataagcagtt atttattgac aacccttttt
      661 aataaatata tcatttgaag tatactgacg aaaaggagtt gaataataat ggacatctta
      721 ttggttgaag atgataagaa tattcgagaa atggtatacg attttctgat tagtgagaat
      781 tattttgtta aaactgccgt tgacggaaat acagctattg aaatatttaa aaattattca
      841 tttgatatta ttttactgga cttgatgtta ccaaagtcta gtggttttga agtattaaaa
      901 tatatacgaa gtgtgagtgt tgttcctgtt attattacta ctgcgaaaga tagtgacaca
      961 gataaaatgc tagggcttaa tcttggtgca gatgattata ttacaaagcc tttttcaatc
     1021 gtagaattgc ttgcaagaat taaagctaat attagacgtg caacggtgta tagcagttca
     1081 agaaactctg aagatatggt tattcagtat aaagatttga ttataaacat atcaaaatat
     1141 gtagtttcaa agaatggaat tgacttaaac ttaacacata cagaatttga aattgttaaa
     1201 ttactagcga ctaatcaagg acgtgctttt tcaaaggaac aattatacaa cactatttgg
     1261 aaagaacctt attatggaaa tgaaaatgtg ctaaatactc atattaacag gttaagaaat
     1321 aaattgtctg atggtataga aaaaaataat tatattaaaa ctctttgggg aattggctac
     1381 aaaatggagg aagaataatg gagttatttt tagttgtaat ttcgattgta ctatttgctt
     1441 tctacttaaa agaacgaaat aagtcaaaga aaatggaaag tgattataag tatatcaatt
     1501 caagacttcg tgatataaca aatgatgatg aaattaatta tattttagta ccatctgata
     1561 tttcgattgt aaaagaaaca gcagtagata taaataaact tcttgaaaag ttttacagta
     1621 ggcaaattaa ttataataga agtgaaaaag cgatattgca aatatttaca aacatatcac
     1681 acgatttacg aactcccatc acagtattaa agggttatat tgaaatgcta tatcttcaaa
     1741 gtcaaaaaga agaattatct tcttcaatga gagcaacttt ggaaaaaatg caaacaaatt
     1801 caaatgagct tgttaattca ataaataacc tgtttaatat ggcaaaaatc caatctggag
     1861 atatgatatt aaatcttcaa aaatccaatc taacacaatt atgtcatgag attattttag
     1921 agttttatga tttactagat aaagaaaact ttaatgttga agttaatatt gaagatagac
     1981 ctatatatgc aaatgttgat acagaagcat tacaacgtat actcaaaaat ttaattgata
     2041 atgctataaa atatggttca gatggtagat ttttagggat ttcactatat gaaaaggaaa
     2101 aacatgtttt tatagatatt gaggataaag gttcaggtat ttctgaaact gaaaaagagc
     2161 atattttcac aagagcttat actgctgaca gaaaaaaagg caatggttta ggtttggcta
     2221 tttctcaagg gcttgcaaac tctatgggag gttcaattta tgtaaatagt agacctaatg
     2281 taaaaacagt ttttacagta aaattgaaaa gttagaaaaa agttagattt aaaagagaga
     2341 aaagataatt ttattttgta tactgttttt agaaaggagg gagtatgatg aactatatca
     2401 tagagaccca tcaattaaag aaaatatata aagataaagc tgttgttaat gctgttaata
     2461 ttcatgtgaa aaagggagaa atttatggat ttgttggacc aaatggagca ggtaaaagta
     2521 cagtaatgaa aatgttgcta aatcttgtta atccaaattc tggagaaata gttatgttcg
     2581 gtaagaaagt ggcagaaact gattttgaaa tattaaaaaa gattggtact attattgaaa
     2641 atccgtattt atatgagaat ttgactgcta aacagaatct tgatttacac tgtgaatata
     2701 tgggttatta taacaaagaa catatatcag aggtattgga atgtgtcgga ttgtcaaagc
     2761 aatcaaacaa gaaagtttca aaatattctt tagggatgaa acaacgtctt gcaatagcta
     2821 gagcaattct tactaaacca gaattattga ttcttgatga acctataaat gcactcgacc
     2881 cagaggggat aagagaaatg cgagaattat tccgtaagtt aaatacagat tatggaataa
     2941 ctatatttat ttctagtcat attctttcag aggtagaaca aattgcggac actattggaa
     3001 ttattcaaga tggtaaactt attaaagaaa tttctatgtc agatatacac aaatatcaaa
     3061 cagattatgt tgaagtagat gtagataatg tggaacttgc tggatacttg ttagaaaaag
     3121 aatttggaat aaaagacttt aaaattactt cggaaagttg tattgaaata tatgatttac
     3181 gaaaagatgt aaaagaaata tccaaaatat ttattcaaaa tcaaattggt ataaatagca
     3241 ttggacgtaa acaaagttct ttagaagatt acttcttcca aactacaggt acaggaggta
     3301 aagaaacact atgatacatt taatgaaact agagctaaaa aaagttgggc taaaaagata
     3361 ttttttattt tcaatactgg ggattttctt atgtatgttt tttgtcttta ctggattgaa
     3421 tgataaatct acttcaatat atgattatga tgttacattt aggacaatca gtttattttt
     3481 ctgtttttac tatattatat tatttgctgt gttgaatgtg gcatatataa taaatgaata
     3541 tacaaataaa acaatcttga ttttattctt ttatccactt gaccgtaaaa aacttatttt
     3601 atcaaagtta cttttgatta cgactcttat gatatcatca atgatagttg gatatatctg
     3661 ttgttttaca ttcgttgttg tgttggataa gtattttaat ttagttattg gagattttca
     3721 tatttcaatt ttatcttatt ggataccagg agcaattaaa agtattatta tattttgctc
     3781 attaggtata tggacattcg ttgttggaat gataagaaaa tcaatacctg ttacccttgt
     3841 cagttcaatt atttttatca atttaagaca atttatttta gctggtacaa atacaactca
     3901 agacagtttg atttctgttt ttattatagt tggtataact gtgattggta tatattatat
     3961 actaaatcat aaagttactg aaattgacta gatactgtgg ctaggaaggt agttattaat
     4021 tgtatcttct tgggataata atgatttgct attatatcag ctattattaa tattattaga
     4081 gttttaataa tattgcacaa ccatttgaag ttgagccaaa gcttgatgaa ttaattgaat
     4141 ggtactatag tcagagtgaa gtgtctatta aagttatagc tgaatttcat tatagatttg
     4201 aattgataca tccatttcaa gatggtaatg gtcgcatagg tagatttgtt atgctaaaac
     4261 agatgttaga aaataatctt cctataaaaa ttgtatcttg ggatagtgag gacttgtata
     4321 gaaactcctt aaattcttgt agtttaggta attatgtccc tttaattgaa tatttatcaa
     4381 gtttagaaga ttttagagaa gtatataaaa tgttatggaa ataattgttt gtagcaaaaa
     4441 aagtttttat ataaatatat ttttaactat gctatttaac gttgatttct tagttattct
     4501 tagcttggac tatacccact attttaacta tataaaatag tggatatagt ttaactatct
     4561 ctttataact atttttatgt atcttagttg tttcttaata ttgggacagt tcataaaact
     4621 aaaagtgatt tttaatttta tcatttataa tttaccatta catcagaaaa atgcttatca
     4681 ttagaatttt cataaaaggt acctattttc ttcaattaac taaatcaatt ctattagtct
     4741 taatctttcg tatttcaaat tgataataca agaaaataaa aaataaaaaa ttttaaattt
     4801 tttatttatt gcgaaaaaaa taaaaaggtg ctatactttt tgtaacatat tattcaaatt
     4861 attaagagat agtaaatatt tatagtttaa tttgtagtac actagcatga tttgcagaac
     4921 aatgaattaa tctatagtat aatagtttaa tttgaagtac aacgatttaa tctatagtac
     4981 actagcatga tttgaagtat aacgatttaa tctatagtac aataacttga tttgcaatac
     5041 aataatttaa tctatagtat aatagtttaa tttgaagtac aacgatttaa tctatagtac
     5101 aataacttga tttgcaatac aatgatttaa tctatagtat aagagcatga tttacagtac
     5161 aataatttaa attgtagtac aaaagtacta tcaaataaga atttctactt taaaaatatt
     5221 actaaaagta attaaaatcc aataattcaa tataatatgg caaaagaata gaaataaggt
     5281 gagagtagtg aaagtaaagt caaatttaga tgaaatttta tatcataaga ttattgaaag
     5341 tcttattcgt ggtgaatact ctgtaggtca aaaaatatta ctaaatgacc tttgtgaaaa
     5401 atttgaagta agcagaacac cagttgtaca agcagtaaaa atgctaaata aagatggagt
     5461 gcttactatt atgacaaatg gtaaagtgta cgtaccagag tatgaatatg atatggtaaa
     5521 acaagtttgt gaaacgagaa cactgattga aacatatgct ttagaaaaaa tgatgcaaga
     5581 agaggaagag gtttttcaac aaaagctaga tgtaataaaa agatactctg ataaatgcga
     5641 ggagtactat cgtcaagaaa aatctgtaga acttgcacta gcagatttgg aattacataa
     5701 agccattgta gaaggggcaa ataatgagat tttaaatgat gtatatgttg gtatacaagg
     5761 aagatttata gtagtgaact atttaattcg accattaaaa aatcgtaatt atgaaggaac
     5821 agtacaagac cattttgaaa tattaaaatt cattgaagac agagatacaa aaaaagcagt
     5881 agataaacta agaaatcata ttcaaggaac tattaaaaga ttctgtgaag atgaataata
     5941 agttttgaag ttactatata tacttatcta ttaagttgct aaatgtagtc taagtataat
     6001 ctaattatag tttaaacata atctaaatat aatctaataa atataatcta ataaatataa
     6061 tctaataaat ataatctaaa tatagtgtaa ataagtctaa gtatgaatta aatatagatt
     6121 aagtatggac taagtataga ttaagtatga attaagcatg gattaaatat actttaaatt
     6181 acaaatatta caaggaagcc agaaggcttc ctaaaaaaat aacctttata aaatttttta
     6241 ttttaaattt aaaatttttt attttaaatt taaaataaaa aatgaaagag gtggtaggga
     6301 gtttgaaaaa aattactaaa gaaaggatag aaaatactat gaaaaagcta tttacgagtg
     6361 aaacattttt ggaatatcaa tttataagtg attgccaaat atcaccagat ggaggatata
     6421 cagcatttat tgtaaaaaaa gctgatatca aagagaatgg ttacacaagc caagtttata
     6481 tattaaacaa taaaactggc gaattaaaac aaataacgtc tataaactct gttggagcat
     6541 atgtctggga agatgaaaat actatcttgt tccctgcttt gcgaaatgaa aaagtaaaag
     6601 aagctgtcaa aaacggtaag caatgcatga gttattatgc tttatcttta aatggtggag
     6661 aagcagaaga actttttaga ctccctatca aaggtggtaa attgaatcat ataggaaaag
     6721 gtttgtatgc agttattgat tcttatgaca atgaccgacc tattgtagag ggattgtcag
     6781 aagaagaaca acagaaaaaa ataaatgctt ataacaaaag acattatgaa catttcaaag
     6841 aaattcctta tgctgtcaat ggggagggat atattagcag aaaaagaaaa cgcctatata
     6901 tatacgacag taatataaat gagttgaagg caattacagc acctatgttt aatgttgtag
     6961 gtatgaaaat aagtgatgga aaaatcttat atatagggca agagtttaaa gatgtaaaag
     7021 gtttgaaaaa tggggtctat gtatttgata caaacacaaa cacaaatatc tgtatattag
     7081 aaaaagataa gtatattata aaaggttttg aattatatca aaatcaagtg atactaaacc
     7141 taactgatgc tttatcttat ggaaatggag aaaatggaga tttttatact attgatattg
     7201 atacgaaaga aatgaaactt ctttcagggc atcaacatca ttgtattgga aatacagtaa
     7261 catctgatgt taaaatgggt gctggtcaga caacaaagtt agatggagaa tatatttatt
     7321 acacttctac agtagatatg gactgcatta ttgaaagaat acatattcca acaggaaaac
     7381 aggaaaaagt aacacagaca ggttcagttg attttataga tgtaaaagat ggcaatattg
     7441 tatgtgtggg ttgtttagga aatggattac cagaagttta tacagtagag aatggaacat
     7501 tgtgtaagaa aacacattta aatgaccata ttttagagga atataaaatt tctgtgccag
     7561 aatacataga gtcaaaagga agttctaaat gggaaataca aggatacgta tataaaccag
     7621 tagattatga ggtggggaaa aaatatccag ctgtattggc gattcatgga ggaccaagat
     7681 tgacatatgg accatatttt atgcatgaga tacaggtatt tacaagtgca ggttactttg
     7741 tattcttctg taacccaagg gggtctgaag gtcgtggcaa tgcttttgca gatattagga
     7801 aacagtttgg agatattgat tatatagatt ttatggaatt tacagatact gtacttgaaa
     7861 aatatacaga cattgataaa acaaaattgg ctgttgaagg tggaagttat ggtggattta
     7921 tgacgaattg gataattggt catacaaacc gttttgctgt tgcttgtgct cagcgttcta
     7981 ttgcaaactg gagtggcatg gagggtacaa cagacattgg ttattatttc tgcaaaggac
     8041 aaacaggtgc ttctcatatg gaaaaccacg agcttcaatg gaaacagtca cctcttgctt
     8101 atgctgataa atgtgttaca ccgactttat ttttacatgg tgaaaaagac tatagatgct
     8161 atatgcaaga agcattccag atgttttcag cattgaaaat tcatgggtgt cctacaaaac
     8221 tttgtctatt tgaaggggaa aaccatgaac tgtctcgttc tggtagacca aaacaaaggc
     8281 tacaaagatt agttgaaatg ctagattggt tttctgtgta cataaaaaaa gataacatag
     8341 gacagtagaa aggagaatat aaaaatggaa aaaataaaga ttgaaagttc agatattttt
     8401 gaatatatat tccctcatga tatttcttgt tcacctgatg gaaagcatat tgcttatatt
     8461 atatcaaata tcaacgagga aaaagactgc tatgaacatg acttatatgt gatggacatc
     8521 aaaacagaaa aacaaataca tatgactcaa acaaaagatg taacatcatt tagttggatt
     8581 tctaatacag aactactttt tacatctaaa agaaataagc caaaagcagg tacaacagat
     8641 ttttacacta tttctataga aggaggagaa gcaaaagaag cattttctat tccaaaagct
     8701 tgtagtgtac ctgtatcact tggaaataaa ttgtggttat tgacaacaaa aaatccaacg
     8761 gattctaaaa aatcagaacc agatagggca gtagagggtg tagattattg gacatttaca
     8821 gataaacctt ttataagaga tggagaaaat ttttctcaaa gaagacgtgt aacattagaa
     8881 ttatatcaag aaggtgaaaa tataacaaaa gccattacac caaaattttg tgaagtagca
     8941 ggtatagacg tttcttctga taaaaacaga attttatata ctggtcagat ttatgaagat
     9001 tgtgcaactc ctttttctgg actttgggag tatcatatag acagtggtga aaccaaagaa
     9061 cttgtaccac aaggaaagta ccaaataagt ttggcaaaat atattggcaa agataaagta
     9121 atgttgcaag cttcaacatt agaacgttct atcacacaga atcatgatat ttttatactt
     9181 gatttgagta ctagtgaaat aaatatgatt gctagtccag atggtatgta tgctacatta
     9241 ctggatgtag atgcagtata tggtggtgga cgtagtaata aagttatagg agataaattt
     9301 attggtgcaa gaatttgcag aactatgaca gaatttaatg agtttgatac aaagacaggt
     9361 aatatacgta tcatcacaaa agtagatgct tttacatctt ttgatattta cgacaacacc
     9421 atgtacacag taatgttgaa agattatgag ttagcagaaa tatatagcat tgatatgact
     9481 acaggtacaa tgaaaaaaat gactgctttt tctaaaccat atttagatac tcataaggtt
     9541 tcattacctg aaaaattgac gtttgtagca aaaaataaag aagaagttga tggttttgtt
     9601 ataccaccta tagatgctaa agaaggcgaa aaatatcctg ctgtattgtt cattcatggt
     9661 ggacctaaat gggcatatgg ctatatgttt acacacttga agcagtgtgt aacatcaaag
     9721 ggaatgtatg tgatttattg taaccctcat ggtggtgacg gttatggtga aaaattctta
     9781 gaaatggtag aaagatgggg gtatgttgac tatgagcatc ttatggaatt tgtagatact
     9841 tgtattgaaa aatatcctgg gattgatgca gaccgcttag gggttgcagg gggaagttac
     9901 ggtggttata tgacaaactg gataattggc catacagacc gtttcaaagc agcagtttct
     9961 caaagaggta ttagtaactt gattacagct tctttaatta ttgactttgg ggatagaatt
    10021 atgaagcaga cttgtggaga taagacgcct tggaatcatg aggaggttct ttggaatcat
    10081 tcacctatta aatatgtgaa aaatgttaag acaccaacat tgttcttaca tagtgatagg
    10141 gattatagat gttttatggg ggatactttc caaatgttta cagcattaaa acagcttggt
    10201 gtagatacag aaatgtattt gttccatgga gatacacatg gattgtctag aaatggaaga
    10261 ccatctaata gaattgcacg agcaaatgct attgtagatt ggtttgaaag atatttataa
    10321 taagggggtt attctatgag tgatatgtta ttatggttta gtgtcgtatt agttttattt
    10381 gctattgggg atttaattgc aagcaaaaca aaagcaaaag tatcagctgt atttgttaca
    10441 ctacttttat ttttgatttt atttgtcaca aaagcaatac cagccgatat tattgaaaaa
    10501 gcaggtatga ccgcagcagc tagttggagt gttccaatga ttatgtttag tatgggaaca
    10561 atgttgaatg ttaaacaatt tatagacgaa tggagaacag tattgacagc atggcttgga
    10621 attgtagcag ttatagtctg tgtctcatta tgtattcctt tgtttggaaa atcaacagta
    10681 ttgacaagca taccagttat aaatggagct ttacctgcta ctactattat gacacaagca
    10741 gcactagaaa aaggactgac acttgcagca gctacagcaa cagttgtatt tgcaattcag
    10801 aagtttattg gtacaccaat agcttcaaga gcagcgttac aagaggcaaa ccgtctttta
    10861 gtagaatatc atgaagcaaa atcaaaagac attgatttag caaatgttga tactgataag
    10921 aaagaagcag agaatacagg cacaaaagta aaacaagctt tctgtgaaaa atacgataaa
    10981 tattattcta caaatgtttg tatatttttt atagcactat tctcttatct agggtatgaa
    11041 ctttcagaga ttattcatgt aaattattct attgtatgtc ttgttgttgg tgttattgta
    11101 acacgtattg gtattgtacc aaaagacatt ttggaaaaag gaaaaatcaa gggatttatt
    11161 aacatggttg tgtttgcagc tgttattcct tctttagcaa aagtttcttt gacagattta
    11221 attagtcttt ttgtaccaat tgtgggtatg tttgcagctt ctatcattgg tatattcctt
    11281 atgatgaagg tgttaccagg ttggaaaatt atcggttcta aacctcttgc ttttggagta
    11341 gggttttgtc agatgttggg attcccaact acatatttaa tttcaaatga agtgtgtaat
    11401 gctgttggag aaacggaaga agaaagagca tatttgatgt ctaagattat gcctaagctg
    11461 gtagttggtg gtatggcttg tatgatttct attgtagtag ctggtcttat ggtaccaatg
    11521 ttgtagatag gtttcatagt taaaaagtgg tgttaattta taggagaagc taaaaagtag
    11581 tattaattta taaaatagtt ttatattagt taatttgtta taagaatatt ttctttttat
    11641 gattataatt ttgattttat aagagagcag attttttatt tgctatgcta atagttataa
    11701 tttgttttta tttgctaaaa tgcaacttta atttgattta tgtataatat agggtattta
    11761 ataatatttt tgaagaattt ttataaaaaa ttaaaaagag gagaaaaaag ggagtgccac
    11821 aaagtgaact ttttagttct aaggcactct tttttgtacg aaatcgaata tattttcagc
    11881 gttttaaaag tgagaaagag acttatctct agtttgagat agccaaattt aattattaaa
    11941 attatttttt gttttattta tcaaagagta ttcgtgtttt agaagttagt attttttatt
    12001 ttatatatcc aaggttttcc gtttctaatg ttttcttttt taaaataatt agggtattca
    12061 attatagtaa aaggtggatg gtattttgga atgatattat ttaaagcaca gtattgaatg
    12121 ttgaaatcct cacattttag agtattatct tttgtaatca aaaaaatctt ctatacttat
    12181 agcaaggtta cttctgcaaa tattccatgc atcataatat ccaaatttaa atttttttaa
    12241 tatagagttt acctctagtc tacactcttg aataactctt tcctctatcc aaattcttat
    12301 aaattcatcc catttattac tatctattta ttactatcta aattttttag tatgtttgta
    12361 attggaaatg gatttattcc tttatgtttt ttataaatag tttataactt aatttattat
    12421 taaacaaatc attcatacag aattactttt tcttttagat attcaattct tacttttaat
    12481 aaatatttaa tacattctat cttatgtggt tttaaaaagt gtttatggct atcaataatc
    12541 tctaatattt cattcatatt tattttgtca tagtaatatt ttacatcttt tatattgaca
    12601 aaaaagtgct ctaagtgtat agtgtgtata taataacatc acactggagg tgataaaaaa
    12661 tgaaagtgct catttctaac acatcagata agccattata ccaacaaatt aaagagcaaa
    12721 ttaaagaagc aatatttact gaagaactga aagaagggga tgcaatgccc tcaataagaa
    12781 attttgctaa tgatttaaaa gttagtattt tgactattag acgagtgtat gaagaacttg
    12841 aaaatgaagg ttttcttaca cgccaagttg gaataggaac atttatttca actggaaatt
    12901 tagaaatact aagagactca aagagacgta tagttgaaca aaaaatggca gatatgatta
    12961 aggatgcaaa agcactagga attacacaga tagagttaca agaaatgatg gatattctat
    13021 atgaggagga ttaatatgga aaatatttta gaagtttata acttaaataa gacttatacc
    13081 aatttttcat tatctaatat aagctttgta ttaccagaag attgtataac tggatttata
    13141 ggtgttaatg gagcaggaaa aacaacaaca attcgttcga tattggatgt cgtaaagcgt
    13201 gatagtggaa aaataaaaat ctttggtaaa gatttcgatg gaaatgagaa ggaattaaaa
    13261 aatcgaattg gagttgtatt tgatgattca tatttctatg aggagttgtc aatgtcagaa
    13321 atgaaaagta ttattgcacc ttcatatgat aattggtgtg aagaagatta tcaacaaaat
    13381 atgaagcgtt ttaatcttaa tccaaaacaa aagattgata cactttcaaa aggaatgaaa
    13441 atgaaatttg ctttagcatt agcattatcg cataaagctg agtttttaat tatggatgag
    13501 cctacaagtg gtttagaccc actaatccgt agtcagatac ttgacatact aacagaatat
    13561 atgaagaaat gtggtcgtgg tgttttcttt tccactcata taacatctga tttagacaaa
    13621 atagcagata tgattgttat gattgacaat ggacgtatta tattagagcg tgaaaaagat
    13681 actctattgg atgaacatag aaaagtaaaa ggggatattc aatttctaaa tgatgaaatc
    13741 aaaaaattat ttttaaattt agaaactaca ggttatggtt ttgtagggat tacctcaaaa
    13801 attaatgaag tgcaaaaaaa tatgccagat attttaatag agcgtcctac aattgaagat
    13861 attatgcttg catatattga aaggagagag taattatgtt gattcattta gttaaaaaag
    13921 atattctgat tgtaaaaaaa tatgtattgt tgatattgtt tattgcaata ggaatcccat
    13981 tatttatatt gtggcgttta cctccatttg cacaaatatt gggatttgta ctatcaatta
    14041 tattttcaga atttatgctg tgccagtatc tcttattaaa ggagagtcaa tattcaaaag
    14101 catctgtatt actttgttca actccttatc ctagacgtgg cttagttcaa tctaagtatg
    14161 ttttatttgc aatggtattt atctattgta cattagttta ctggattgaa aatttactta
    14221 ttccacaaat aggaactttt gacttaacat atattttgat tgttttatta ataagttcta
    14281 ttatttatgg agtttatatg cctattcaat acaaattagg atatgaaaca acaaaattct
    14341 ttttcgtgat gataatcatg gcttcatcat ttgtattacc attaactata gctcacagca
    14401 attttgaaat tccatttata tatcagtatc catccatgat agtgaatatt gtattgttcc
    14461 ttttaagttt aattatactg ctagcttcaa tgtttatttc tattaaaatt tttagtaata
    14521 aggagcttgt ataaggtaag ggggaatttt atatgccaca tttgccagat tgggctgttt
    14581 tactttgtat cttacttcca atagtatata aagcttgtca gatatttaaa agtaaaaaat
    14641 agagtacata tttatattgc catttttatt gagtgaagtt agatggtatg aatttaaaag
    14701 gttacttgaa aataaagtta cttggtgtgg gagagtaaca tcataatatt atagattata
    14761 tgtttcttgt gaatcaattt gtatttttta atagataata tccagtaatt ttattttcca
    14821 ttgattattt tcaattatga gtatgattgt gtgtattgta taccatcttt taaggtgttt
    14881 ttaaaaaatt atatcgtcaa aatataaatc taaggaatcc tataaataaa gcttttcaat
    14941 tttagaaaac taataaaaag taggaagtta ataaaaagaa gctgtctcaa aatagagata
    15001 agcttctttt tcattgctga aatgacgaaa atataattga tttaatataa aaaagagtgc
    15061 tttatgaact atttattttg aacagtagat acacttgcac tcaatttagt tactcctaag
    15121 ctttatgaac taaaagttta ttttgaagcc tatttttatt aaaagagatt ttatttttct
    15181 aaataatcat ctatatacag tattgcgttt cttttattta ttcataattt attttcttat
    15241 taaagttttt ctatattcat attttctata ttactttact tttaatttta tacgaattat
    15301 caaaaataaa atagttatta gaaaaaaata aaagtaattg caaagattgc aattacttac
    15361 ttctatatta attactatac cataaaataa caaaaaaatc aagtcgagta atccttcaac
    15421 ttaagtgata tactaggtat taataatttt taattaataa aatataacta gaggaaaatc
    15481 tacattttct caatttcttt aattaaattg acctctaatt aagtaattat aaggagaaaa
    15541 attatgaatt tagcaaaggg attagatgtt ttaaaaattt catcaaatgt attcggtgaa
    15601 gataaagtta tgtatattcc tgtaatctac acagaagatg atgcaacact tattgacaca
    15661 ggtcttccgg gtcaaggtga tttaataatt gatgctctta ataaaagtaa cacgagcttt
    15721 gataggttaa aaaatataat aattactcat catgatatag accatatagg aaacataaat
    15781 tatctaagag aaaaatctaa gaataatatc aaagtatatg catacaaaag tgaagtcagt
    15841 tatataacag gagaagaaac tccttttaaa ctttatatgt tggaacaaat ggtagctaaa
    15901 attgatgata agatgcttag tatgctaaat gttatgagac ttggatttaa atcatcatat
    15961 actaaagtag atgtgtcatt agataaccat gaaaaattga atctaggtga ggaaatagaa
    16021 gttatacata caggaggtca cactagaggt cacatatgtc tttatttaaa agagtctaaa
    16081 gtacttattg ctggagattt gttacaggta gaaaatggag aacttacgcc tgttgatgta
    16141 atgcacagca acaaacaaga gttaaaagat gctattaaaa atataagtaa ttatgatata
    16201 gaaacgatag tttttagtca tggtggatta tatcaaagag acataattgg aacattgaaa
    16261 aacctaatta ttgaatagta ctatatgatt tacaataatt tcttaaatta cttaaaatta
    16321 tatctaaaga tgtagaatca aaattaaata taagtaataa gaattttgct ttaaaattat
    16381 aattaagtgt taagtatgat acgtagtatt acaagtattt tagaatataa ttttttatag
    16441 taattttaag gttctacaat acttcagttg aaaaatattt aacagcatag tataatagga
    16501 aagaaaatat tttaaataaa ctttagtata caaagtgaag aaaaatattt aaattatata
    16561 taatattgta gagtgaggta aaatatttaa gttatatatc ataatacaga gtgaagaaaa
    16621 atatttagat aatgtaccat aatacaaggt gagtaaaaat atttaaagca tgtataataa
    16681 tgcaaagcga agaaaaatat ttaaataatg taccataatg caaagcgaag aaaaatattt
    16741 aaataatgta ccataatgca gagtgagtaa aaatatttaa ataatgtgtt ataatacaaa
    16801 gcgaataaga ttatttaaag catgtattat aatataaagt gagtaaaaat atttaaatca
    16861 tgtatcataa tataagcaga gtgaagaaaa atatttaaat aatatatcat aatgtagagt
    16921 gaggtaaaat atttaagtta tgtatcataa tacaaagtaa agaaaatcat ttaaattata
    16981 tatcataaaa ataatatgaa atattgaaca ctcataatat tggaggcttt aatattttaa
    17041 ttgataggtt acattattta taacattaaa aatacaattt acataaaata gacatatgaa
    17101 aaataaaaaa ttatataata attatgggaa tgaggttctc ccttggatga taatatccta
    17161 aactgccaat gagctgatga cttctatgat atcatagatg ccaccagctt ttttgttgtt
    17221 taaatcgata aaatggaggt gaattactta ctaaattttt attttttaaa tttgaagaaa
    17281 tatttgatta atagaaaaaa cagtagatta tatgttaatt attttatcaa gaatgggtta
    17341 agagtatacc tatatcctat caatttaaaa aacaattatg atagtcatta cattgactac
    17401 agttgatgca ataaaacttt caaaaaatct tatgatgcaa atagaaagga attaaaatga
    17461 tagaaaaatt taaaacttta atatggatta aaatgataat aagaattaaa agcgtttata
    17521 aaacatatgg tggactattt ttgttaggac tcataggtat accagttggt gcaattatag
    17581 gtcttataga caccatattt ggaacggttc ttctaaaagt tacagatatt cgagaaacat
    17641 atccaatgta tctgatacca tttttagcag tagtaggagt tgttattgct tattgctatt
    17701 ttaaatttgg aggaaaaagt agtaaaggaa tgaatctaat atttgaggta gggcatggag
    17761 aagaagaaat tattccttta agattggttc catttataat atcaggtaca tggttaaccc
    17821 atttatttgg tggtagtgca ggacgagaag gagttgctgt tcagattggt gcaacttttt
    17881 cacattggtt aggtaaaagg ttgcctataa aaaatgattc tagtattttt ctagtaactg
    17941 gtatggcagc tggttttgca ggattatttg agacaccaat agcagcaata ctatttgcta
    18001 tggaggtttt ggtagctggt tcactggagt atcaatcgct ttttcctgcg tttactgctt
    18061 cttttacagc aagtgcagta tcaaaagctt tagggttaga gaaattttct tttgcacttt
    18121 cttctaaagt tgtatttgac ttatcaatat tttggaagct tattgctttg ggaattgttt
    18181 ttggaatggt tggaggagca tttgcatggt gcctgaaatt gtcaaaaaga aaaataggta
    18241 atagattaaa aaatcctatg ataaggattg ctgttattgg agtttgtctt agtgtattat
    18301 tccttttatt ttataaagga agatattcag gtttagggac aaatttaatt caaaatagtt
    18361 tttatggtgg agaaatttat tcatttgact ggctgttaaa gtttatactt acaatactga
    18421 ctttgtcagc aggttttcaa ggaggagagg ttacaccttt gttttccatt ggagctagtc
    18481 ttggtgtatt gttagcagga ttttttaatt tgccaattga attagttgca gcgcttggct
    18541 atgctagcgt ctttggcagt gctacaaata ctttttttgc acctgtattt ataggggcag
    18601 aagtttttgg atacagctat ttaccttatt tctttgtagt atgcgctatt tcatatatat
    18661 ttaatatgga taaatctatt tattcactac aaaaaatttc aacaaaacaa taaataaaac
    18721 aacataatgt atgattagaa gagaaagaat attagagaaa ggatagggta ggaatatgtt
    18781 gacaagttta gctttgattt ttttattagg aatggcctcg ggaggtattt ttaagaggat
    18841 aaaattacct aacttattgg gaatgttact tacaggaatc atattaggtc catatgtttt
    18901 aaatttgatt gataattcaa tactagatat ttcttctgac cttagaaaga ttgcattgat
    18961 tattatatta acaagggctg gattatcttt agatataaac gatttgaaga aagtgggaag
    19021 acctgctgta cttatgtgat ttattccagc tacttttgaa attatcggaa tgatagtttt
    19081 agcaccaaaa ttactaggcg tttctatatt ggaagcagca gtcatgggtg cagtagtagg
    19141 agcagtttct cctgcaatta ttgtacctaa aatgcttaaa ttaatggaag aaggttatgg
    19201 tacagaaaaa agtattccac agatgctttt agcaggaact tctatagacg atattttcgt
    19261 aattgtgatg tttacagtat tcacaggatt ggcacaagga aatagtatat cagctattag
    19321 ttttttacaa attccagtat caattatatt aggtgcaata gctggagcag tgattggaat
    19381 ctgtttagcg gtatttttta agaaggttca tatgagagat tctgctaaag gggtgttgct
    19441 tttaagtatc tcatttttaa tgataagttt ggagactgct ttagagggta ttgtgccatt
    19501 ttctggatta ttagcagtta tgaatattgg gattttcctt cagataaaat atcgtgtagt
    19561 tgcaagaaga ttgtctgtaa agtattcaaa actatgggtt ggtgctgaaa ttctcttgtt
    19621 tgttttggta ggggcaacag tagatataag ttatgcattt aaagcaggaa ttggagctgt
    19681 aattttaata tttggagttc ttttattccg tatggtagga gtattcttct gccttattaa
    19741 gacaaatttg acaataaaag aaagattgtt ctgtatgatt ggctatattc caaaggctac
    19801 agtacaggca gcaataggag gtgtaccact tgcaatgggg atggcatctg gacaacttat
    19861 tttgacgtta gcggttctcg ctatacttat aactgcacct cttggagctt ttggaattga
    19921 tgtaacttat aaaaaattat taacttctgt agaaggtaag agtaagtaag aataaaaata
    19981 aagattattt taagtgataa attatatttt ggaaaaaact atattattga gtacaatgtt
    20041 agaaaatcat ttgagtgatt acagaaggta gaagtttata tcggatttta aggcatgtga
    20101 tgattattag aattgatttt gtgaaattgt tattgtaata tttaattata tagataaaga
    20161 agcggagtga taactatgta tttaaaaaaa ttatcaaaat tagagttagt tattatgaaa
    20221 tttatttgga atttagatat aaaaaccaat tcatatgaga ttattgatta tatgaaagaa
    20281 gaacataatt taccagaaaa agtagcttta aaaactttat caaaactatc aaagaaaaga
    20341 ttcttatatg ttcaagaaac aggcaagtgt atgtattata cagttgcaat aaaagaaaag
    20401 acatatttag agtttatatc aagaagtgta caaaatcttt tgaagaataa ttttataagg
    20461 aatttattag tatcatttca cgaagaggag ctaacagagg aaaagataaa atcgttagaa
    20521 aactgggtag taaattggga agaagcttat atataaatgt tattattttt attacaattt
    20581 agataatttt ggttttgtaa gctctgcaac tatttttaga tggttgcagg gcttattttt
    20641 attttttatt ccattaggta atacttaaaa gtaaatgtct ttatatttac taacttcaat
    20701 aactcttaat acttagatta ctttttaaaa atattttgat atgtcatctc tatagtaatc
    20761 taaaacttgt ttctattctt tatataaagt ttttaattat tagagatgat tagatttaaa
    20821 ctaaattatc ctaacttatt agacttgtat ttaaaacata tttgtcttaa attttaaatt
    20881 tttacataga ctaaaaaagt ttttatgaat gatatatata atattcgttc atttaattaa
    20941 aaataacaaa atattaaaca attctactct ggtagcgtgt taaaaaaata ataaaaaata
    21001 ttaataaaca aacaaaaatt atcttaagag aggaaaatat tctaaaatat aaaaagattt
    21061 ctagatttca taaaagatac tattttagtc ttgaaaatat ttaatttgga aaaattttaa
    21121 tttaatgatt gattaagtta agagtgtgta tgtaataaat tttattttat ttattgaat
//
LOCUS       DACTZW010000075        20718 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.075, whole genome shotgun sequence.
ACCESSION   DACTZW010000075 DACTZW010000000
VERSION     DACTZW010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20718
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.075"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            353..3400
                     /locus_tag="JAM15_14245"
     CDS             353..3400
                     /locus_tag="JAM15_14245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009757279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HAT6799416.1"
                     /translation="MKKILKRLCTGFLAFATVVTALPSSTVHASNTQYWTESKERVGI
                     VEQVMNDGSISSTFNEGHLTVEGEDAYCIDINTAFKNGYKTKADASTRMSADQIADVA
                     LSIEYVKQYTDSHSGISSKHAYLLRQLVVWQRLSVQLDWQCDNVRASYDEIPKAVQDE
                     VFAGAKAFVKENKGRYDCGGYIYSGEGQELGQFWAKLAVGNTKLQKTSTNANITDGNG
                     IYSIAGATYGVYSDKDCTKQLATLTTDTSGNTEAVEVRATIVYIKELSAPAGFKIDKT
                     VYSLSVEVGKTATLKVSDTPKVTDTLIELFKIDMETQKSNPQGNASLEGAEFTWNFYA
                     GYYNKNNLPAQPTRTWVTKTIAEKDSDGAIHYITRLADKYKVSGDSFYTQDGKNVLPL
                     GTLTVEETKSPSGYLLEGTYMQADGSEEQIKGMYLTQITEDDDLAVLSGSNQYHVSDK
                     VIRGGVKIQKRDLETKDTKAQGGATLKDTAFEIISLNENAVLVEGKLYKKNEVLKTIH
                     TDIEGIASTSADLLPYGKYRLSEQKPPEGYLTDGAKPIDFEITENGKIVDLTDEAHSI
                     YNQIKRGDIEGVKIGAGSHKRLADVPFRITSKTTGESHVVVTDDNGQFSTASDWASHK
                     HNTNAGKTSEDGVWFGTSEPDDSKGALLYDTYIIEELRCESNKGFKLIPPFEIVISRN
                     KVVVDLGTLTDEYEKEITIHTTSTSKDGEKTILAGKDVTITDTVKLDGLTKGTKYQLK
                     GWQMLKEENAELIINNKRVENDYTFVADDEAMKVEIAYTFNASALGGKNLVTFEELYD
                     LSNPEEPVKVAEHKDIDDDGQTVLITERIIKIHTIATDKDGKKEIEAGKDVTIVDTVK
                     LEGLEVGTKYQLVGWQMLKEENAELIINNKHVENDYIFTADSETMEVKIEFTFDASTL
                     GGKQLVTFEELYDLSNPDKPIKVTEHNDIEDDGQTVAIKELPETPTPEEPEKPTTPDT
                     PTKTDSPKTGDNTNILAFAIMMFVSAGGLAGTYFFKHRKMKKS"
     gene            3413..3601
                     /locus_tag="JAM15_14250"
                     /pseudo
     CDS             3413..3601
                     /locus_tag="JAM15_14250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843347.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3625..3948
                     /locus_tag="JAM15_14255"
     CDS             3625..3948
                     /locus_tag="JAM15_14255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014080830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAT6799417.1"
                     /translation="MELKYIVPNVAQTFGNLEFAGENKVDQQRINGRYTLVSRSYNLY
                     SDIQRADDIIVVLPAKAGEKHFKPEQKVKLINPRITAEGYNVKGRGFTNYILMADDML
                     PAESK"
     gene            3963..4346
                     /locus_tag="JAM15_14260"
     CDS             3963..4346
                     /locus_tag="JAM15_14260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005611082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAT6799418.1"
                     /translation="MRLANGIVLDNEKTFGVLKFSALRHEVRVENEDGTTSDEIKRRT
                     YDLKCSVQERMIQVSIPADVPVKDFPYNAEVELINPVADTVANANFRGTTVDWYIKAD
                     DIVLKNKGGQAGNPQNNAPQGQQKK"
     gene            4442..4855
                     /locus_tag="JAM15_14265"
     CDS             4442..4855
                     /locus_tag="JAM15_14265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HAT6799419.1"
                     /translation="MLDKIPNAEEMTALVGQSLYSVWNELCALIDEKYEMECLWNKGG
                     KAWNYEYKYRRGGKTLCALYARENCVGFMIILGKDERLKFDTYRDNYSKEVQRIYDET
                     KTYHDGKWLMFEPTDTTLFDDFVKLLRIKRKPNRK"
     gene            4962..5420
                     /locus_tag="JAM15_14270"
     CDS             4962..5420
                     /locus_tag="JAM15_14270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAT6799420.1"
                     /translation="MKLKNPMLVVTDIDKSVGFYKKVFGLYVIMDFGANKTLTGGLAL
                     QTSETYKEFIGTSDISFGGNNFEVYFEEEDFDKFADRLKEYDIEYVHPIIEHSWGQRV
                     VRFYDPDKHIIEVGENMKIVCKRFLNSGMTPEQVAERMDVPMKFINACMR"
     gene            5445..5987
                     /locus_tag="JAM15_14275"
     CDS             5445..5987
                     /locus_tag="JAM15_14275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HAT6799421.1"
                     /translation="MKGFERKNQLFSLCGLNCGLCPMLLGNYCGGCGNGNQSCRIAKC
                     SLEHGQIEYCYECKQYPCEKYQHIDDYDSFITHKRRKADLERAKNIGIEQYNLEQQEK
                     TQILSYLLSNYNDGRRKTFFCVAVNLLELSELQEAMKQIQSNDELTLLPFKAQCLYVV
                     EVFQKIAERRNIKLKLFKKK"
     gene            6044..6550
                     /locus_tag="JAM15_14280"
     CDS             6044..6550
                     /locus_tag="JAM15_14280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcxB family protein"
                     /protein_id="HAT6799422.1"
                     /translation="METVELRFQYTQSEYIKAERQYLISSKTIHKYDIALVAVFLLLS
                     VFYMLFSSFSVFSILIFGLIIVVTALGSYLYILMPILKFKQTAKYHEEYTLVFSKENI
                     KFKTQSIDSEVKWDIYSALWESHDFYYLIQAPRLYTLIPKRVFKDLNEKQLFEEIAQS
                     RVKTTKHI"
     gene            6660..8054
                     /locus_tag="JAM15_14285"
     CDS             6660..8054
                     /locus_tag="JAM15_14285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008977183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAT6799423.1"
                     /translation="MRMILNKGHRIRARDKNLVYHFSIGTLLFVFVAVLLLLNIKQLM
                     RTDWEHFSLLDNGLTLSPYNFITILIATGICALVAFLYYRFCYDSFKKLLHRQKLARM
                     ILENKWYEADTVQDSGFFTDLQSRSREKIVWFPKIYYQMENGLLHIHCEITLGKYQDQ
                     LLRLEDKLESGLYCELTDKTLHDGYIEYTLLYDMIANRISIDEVKAENGCLRLMKNLV
                     WEYDVLPHALIAGGTGGGKTYFLLTLIEALLHTNAVLYILDPKNADLADLGTVMGNVY
                     HTKEDMIDCVNAFYEGMVQRSEEMKQHPDYKTGENYAYLGLPPCFLIFDEYVAFFEML
                     GTKESVSLLSQLKKIVMLGRQAGYFLIVACQRPDAKYFSDGIRDNFNFRVGLGRISEL
                     GYGMLFGSDVKKQFFQKRIKGRGYCDVGTSVISEFYTPLVPKGHDFLQTIGSLAFVRQ
                     DGTATCEAKGDGTD"
     gene            8334..9455
                     /locus_tag="JAM15_14290"
                     /pseudo
     CDS             8334..9455
                     /locus_tag="JAM15_14290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436855.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
     gene            9462..9596
                     /locus_tag="JAM15_14295"
     CDS             9462..9596
                     /locus_tag="JAM15_14295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HAT6799424.1"
                     /translation="MWELIKDLLLVSLGMGIGVVLMCIMSVGKEADRHMIELKESEEK
                     "
     gene            9597..9818
                     /locus_tag="JAM15_14300"
     CDS             9597..9818
                     /locus_tag="JAM15_14300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799425.1"
                     /translation="MNFGQNLYTWFLSNAQSLVLMAIVVIGIYLGFKREFSKLIGFLV
                     VALVAVGLVFNTGGVKDVLLELFNKIIGA"
     gene            10138..10776
                     /locus_tag="JAM15_14305"
     CDS             10138..10776
                     /locus_tag="JAM15_14305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloramphenicol acetyltransferase CAT"
                     /protein_id="HAT6799426.1"
                     /translation="MEYKYTKIDLNKWNRGKLFQSYIDNMRIVMSLTVDIDVTKFIEF
                     SKKHDLKFYPAMIWAVSKVVNEHDEFKYSWDNNGNLIKWDYISPSYTEFHKEDENFTK
                     IVTDFSDSIFEFHKRFILDREKYKTERAFVENQSLNFFDVSCLPWVKYNHFDVHVFDE
                     GKFLAPVITWGKYELEQERYIMPLTMNIHHAVADGFHLSRFFNEVQELINSI"
     gene            10864..11052
                     /locus_tag="JAM15_14310"
     CDS             10864..11052
                     /locus_tag="JAM15_14310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799427.1"
                     /translation="MKDIFSDMQASIGCTYISDLPHHKRMVWQEMKRLNLADYPQKQL
                     EDFAGYVFGVPYTSIAEA"
     gene            11073..11570
                     /locus_tag="JAM15_14315"
     CDS             11073..11570
                     /locus_tag="JAM15_14315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAT6799428.1"
                     /translation="MNEMRVCIESRLHTSEEIRSAWFTLPIDEEELEEQIGVPIDSED
                     YHIVEKELPFADEVGEDATIEKLNDLYHTFESLPADLQEDYGELMCYFTSLDELHQHR
                     HDVIHYSWCKNMADVARHLLDNDPAFSAIEERLTRYFDYEAYGQYLDDNGKFIETDHG
                     IYELP"
     gene            11586..12089
                     /locus_tag="JAM15_14320"
     CDS             11586..12089
                     /locus_tag="JAM15_14320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAT6799429.1"
                     /translation="MVEDMRVYIANLGKYNEGYLVGDWFSFPIDEEDVAERIGLNERY
                     EEYAVHDTENFPIEIGEYISIEELNEMYEMICELPDYITDSLDEFVSNYGSLEELCDH
                     RDDMILYAGCEDMTDVAYYFIDELQALGDIPPSLQNYIDYEAYGRDLSFEGTFIETRY
                     GMCEIPW"
     gene            12052..12192
                     /locus_tag="JAM15_14325"
     CDS             12052..12192
                     /locus_tag="JAM15_14325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006857179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799430.1"
                     /translation="MKQDTVCVRYRGKKLEDQRQALLLLTAFSIGDSLKNGCPFLLYE
                     RS"
     gene            12202..12591
                     /locus_tag="JAM15_14330"
     CDS             12202..12591
                     /locus_tag="JAM15_14330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAT6799431.1"
                     /translation="MKKIKSYTGIWNVEKVLYAINDFNLPFPVTFTQITWFVITEFII
                     ILFGDLPPLSMIEGAFLKYFGIPVALTWFMSQKIFDGKKPYSFLKSQITFALRPKITY
                     AGKAVKLDKQVLHEAITAVRSVSYVPD"
     gene            12578..15028
                     /locus_tag="JAM15_14335"
     CDS             12578..15028
                     /locus_tag="JAM15_14335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAT6799432.1"
                     /translation="MFPIKYIDNNLVWNKDNEVFAYYELIPYNYSFLSAEQKFIVHDS
                     FRQLIAQSREGKIHALQIATESSSRSIQEQSKKLVTGRLKDVAYQKIDEQTEALVSMI
                     GDNQVDYRFFLGFKLMVTDQSMNLKSVKQSAFLTFKEFIHEVNHTLMNDFVSMPNDEI
                     NRYMKMEKLLENKISRRFKVRRLDKNDFGYLIEHIYGRDGVAYEDYEYSLPKKKLKKE
                     TLITHYDLIRPTRCLVEESQRHLRLEHEDSESYVSYFTVNAIVGELDFPSSEIFYFQQ
                     QQFTFPVDTSMNVEIVENRKALSTVRNKKKELKDLDNHAYQSGSETSSNVVDALDSVD
                     ELETDLDQSKESMYKLSYVIRVSAPDLDELKRRCDEVKDFYDDLNVKLVRPAGDMLGL
                     HSEFLPASKRYINDYVQYVKSDFLAGLGFGATQQLGENTGIYIGYSVDTGRNVYLQPS
                     LASQGVKGTVTNALASAFVGSLGGGKSFCNNLLVYYSVLFGGQAVILDPKSERGNWKE
                     TLPEIAHEINIVNLTSDRENAGLLDPFVIMQNVKDAESLAIDILTFLTGISSRDGEKF
                     PVLRKAVRAVTQSDQRGLLHVIEELRKEDTPISCNIADHIDSFTDYDFAHLLFSDGTV
                     QNAISLDNQLNIIQVADLVLPDKDTTFEEYTTIELLSVSMLIVISTFALDFIHSDRSV
                     FKIVDLDEAWAFLNVAQGETLSNKLVRAGRAMNAGVYFVTQSSGDVSKESLKNNIGLK
                     SAFRSTDINEIKQTLEFFSIDKEDENNQKRLRDLENGQCLLQDLYGRVGVVQIHPVFE
                     ELLHAFDTRPPIQRNEVE"
     gene            15028..17161
                     /locus_tag="JAM15_14340"
                     /pseudo
     CDS             15028..17161
                     /locus_tag="JAM15_14340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323347.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
     gene            17158..18165
                     /locus_tag="JAM15_14345"
     CDS             17158..18165
                     /locus_tag="JAM15_14345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HAT6799433.1"
                     /translation="MKLRHIAIVGSLFSILFSLVLFFGVLISAEDDDGGNGYSSNYVG
                     MNLSAEVLKHQPMVEKYAKENGISEYVNVLLVIIQVESGGTAEDVMQSSESLGLPPNS
                     LDTESSIKQGCKYFASLLSSCKNQGISDINVVIQSYNYGGGYVGYVAGNGKKHMFNLA
                     ENFARDKSGGQKVTYTNPIAVAKNGGWRYGYGNMFYVELVNQYLVVNQVSGELAQKVM
                     NEALKYQGWKYVYGGSNPNTSFDCSGLVQWCYNKAGVSLPRTAQNQYDATQHIPLSQA
                     KAGDLVFFHSTYNAGSYVTHVGIYVGNTQMYHAGDPIGYADLNNAYWQQHLICAGRIK
                     Q"
     gene            18181..19074
                     /locus_tag="JAM15_14350"
     CDS             18181..19074
                     /locus_tag="JAM15_14350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAT6799434.1"
                     /translation="MFKKKEKPVKETKVRTMKVGTHKKSVIALWVVLIASVSFGVYKN
                     FTAIDMHTVHETETIQLRLNDTNGVENFVKNFCKSYYTWDNSKEAIEARTQAISNYLT
                     KELQDLNLDTIRTDIPTSSTVTNVLIWDIKQSGTNDFIATYEVDQQIKEGEQTSNVKA
                     TYTVKVHVDKDGDMVIVQNPTIAPAIEKSDYEPKAQEADASVDADTVNDATAFLETFF
                     KLYPTATEKELAYYVAGNVLEPIGKDYLYSELVNPVFTADGDNVKVKVAVRFIDNQTK
                     ATQVSQFELMLHKDSNWKIIM"
     gene            19287..20144
                     /locus_tag="JAM15_14355"
     CDS             19287..20144
                     /locus_tag="JAM15_14355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAT6799435.1"
                     /translation="MYKEVGISSNNVPITLSIWYTERSSPTIVFLPGTMSHPLMYENF
                     LCGLSERGFNIIGIHYLSHGKSPKIKKNYTMEDLLHNVYDATTYGIENFGENIAVMGS
                     SQGGILAAMAAGRDTRLKAVFPHNIMLTTLKETMSLTKYPAWSHRFMGLIQLGFRVGG
                     KLLPNYKVPGDAYLDYDRVFYSEQAKQDCLNDPMLLPYYPLRFVASLFNADLSCLENG
                     AIQCPVILITAKGDPLFSFDYTNKVFDLIHVPKKELLTLELNRHMIFNEDTDTTINAL
                     EPTLHKYLG"
     gene            20216..>20718
                     /locus_tag="JAM15_14360"
     CDS             20216..>20718
                     /locus_tag="JAM15_14360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAT6799436.1"
                     /translation="MSLPRFTEQEKEIISSKLLIEGEKLFALHGLKKVTVDDLVAAVN
                     ISKGSFYAFYPSKEHLYVDINFRLQKELFTSIETTVKKKKYKNHRDLAKDVIMLSLTG
                     VITSPILSQIDLSLMDYLQRKISSDIFENHMYSDISILEILEGLGVVFLVPHTVIIKS
                     LYSVLSC"
BASE COUNT         6696 a         3797 c         4605 g         5620 t
ORIGIN      
        1 atacaattat ttataaaatc tttgataaaa atttataaat agagcatctt tagaaaacta
       61 ttaacagaaa aacacactaa aaatttgatt atccgctaaa acactgtatc tatcggcatt
      121 atcaaggagc taaacacatc aaaatactac taatttacta cgattgaatg agccttgata
      181 cgtcctattt cccagatatg caaagatacg gtacagcaca tcagtattga aacaagaaaa
      241 attgaatact tcatagacta cggaacgcac aatatcagcg ttccttttct atttccagcc
      301 gttcctagtg gacggctatt ttactaccaa aatgaaagga gcatttagag ttatgaaaaa
      361 gatattaaaa cgattgtgta caggctttct tgcctttgca actgtcgtta ccgctttacc
      421 gagttcaacg gttcatgcgt ctaatacaca gtattggacg gaaagtaaag agcgtgtcgg
      481 tatcgtagaa caagtaatga atgacggttc tatcagttct acctttaatg agggacattt
      541 aaccgttgag ggcgaggacg cttattgtat cgacatcaac acagccttta aaaacggcta
      601 taagaccaaa gctgacgcaa gtacccgtat gagtgccgac cagatagctg acgtcgcctt
      661 atctattgag tatgtgaaac agtacacaga cagccacagc ggaataagca gtaaacacgc
      721 ctacctatta agacagcttg ttgtctggca gagattaagt gttcagcttg actggcaatg
      781 cgataatgtg cgagcttcct atgatgaaat cccaaaagcc gtacaagatg aagtattcgc
      841 aggagcaaaa gcctttgtga aagaaaacaa aggacgttat gactgtggcg gatatatcta
      901 ctctggcgag ggtcaagagt tagggcaatt ctgggcgaag ttagctgtcg gaaataccaa
      961 acttcaaaag acttccacca atgccaatat tacagacggc aacgggattt attcaatcgc
     1021 tggtgcaaca tacggtgtgt attctgataa agactgcacg aaacagcttg ccacccttac
     1081 gactgatact agcggaaata cagaagccgt tgaagtaaga gccactatag tatatatcaa
     1141 ggaactttct gcaccagcag gatttaaaat tgataaaaca gtttactctt tatctgtgga
     1201 agttggaaaa acagcgactt taaaagtatc tgatacacca aaagtaacag ataccttgat
     1261 tgagctattc aagattgaca tggaaacaca gaaatccaat ccgcagggaa acgcttcttt
     1321 agagggagca gagtttacat ggaacttcta cgctggatat tacaacaaaa acaatcttcc
     1381 agcacagcct acaagaacat gggtaacaaa gactatcgct gaaaaagaca gcgacggtgc
     1441 tatccattac attactcgtt tagctgacaa atataaagta tctggggaca gcttctatac
     1501 gcaggacggt aaaaacgtac ttccattagg aacactaact gttgaggaaa caaaaagtcc
     1561 gtcgggttac ttgttagagg gtacatatat gcaggctgac ggtagcgaag aacagataaa
     1621 aggaatgtat ctgacacaga ttacagagga cgacgacctt gccgtattat ctggaagcaa
     1681 tcaataccat gtttctgata aagtcattcg tggcggtgtg aaaatccaga aacgagattt
     1741 agaaaccaaa gacacgaaag ctcaaggcgg tgcgactttg aaagataccg cctttgaaat
     1801 catttcctta aatgagaatg ccgtcttagt tgagggcaag ttatacaaga aaaatgaagt
     1861 gttaaagaca atccataccg acattgaggg tatcgcttct acttctgctg acctattacc
     1921 ttacggaaaa tacagattgt ctgaacaaaa accgccagag ggatatttga ctgacggtgc
     1981 aaagccgatt gattttgaaa tcacagaaaa tggaaaaatc gttgatttga ctgacgaagc
     2041 ccactctatc tataaccaga ttaaacgtgg cgatattgag ggcgtaaaaa ttggtgcagg
     2101 ttcgcacaag cgtcttgcag atgttccgtt taggatcaca agcaagacga cgggcgaaag
     2161 tcatgttgtt gtaactgatg ataacggaca attctctact gcttctgatt gggcttccca
     2221 caagcacaat accaatgcag gaaaaacaag cgaggacggt gtgtggtttg gtacttctga
     2281 accagacgac agcaaaggtg cgttgcttta tgatacttac atcattgaag aattacgttg
     2341 tgaaagcaac aaaggtttca aacttattcc accgtttgag attgtcattt ccagaaataa
     2401 ggttgtggtt gatttaggta cgctgactga tgaatacgaa aaagaaatca ctatccatac
     2461 tacctctacc agcaaggacg gcgaaaagac tattcttgct gggaaagacg taactatcac
     2521 tgatacagtt aaattagacg gtcttaccaa agggacaaaa tatcagttga aaggctggca
     2581 gatgttaaaa gaagaaaatg cagagctaat catcaataac aagcgtgtgg aaaatgacta
     2641 tacttttgtt gctgatgatg aagctatgaa agtggaaatc gcttatactt tcaatgcgtc
     2701 tgctcttggc ggtaagaacc ttgtaacctt tgaggaatta tacgatttaa gcaatccaga
     2761 agaacccgta aaagttgcgg aacacaagga cattgatgac gacggacaga cagtgcttat
     2821 cacagagcgt atcatcaaaa ttcatacgat agctacggat aaagacggca agaaagagat
     2881 tgaagctgga aaagacgtaa ctatcgttga tacagtcaag ttagagggtt tagaagtcgg
     2941 tacgaaatat cagcttgtgg gctggcagat gttaaaagaa gaaaatgcag agcttatcat
     3001 caataataaa catgttgaaa atgactacat ctttacggct gacagcgaaa ctatggaagt
     3061 taaaatcgag tttacctttg acgcttccac tcttggcggt aaacagcttg taacttttga
     3121 ggaattatac gatttaagca atccagacaa acctatcaaa gttacggagc ataatgacat
     3181 tgaggacgac ggacagacag ttgctatcaa ggaactacca gaaacaccta ccccagaaga
     3241 accagagaag ccaaccacac cagatacacc tacgaaaaca gacagcccca aaacgggcga
     3301 caatacaaat atccttgcct ttgcaattat gatgtttgtt tctgctggtg ggctggctgg
     3361 tacatacttt ttcaaacacc gtaagatgaa gaaatcataa ggcggtagct gtatgagaaa
     3421 agaaaaatca cgctctccgc catagcttag ataggcagac tatacctatt ctggcttgtc
     3481 tgccgattac ctgcaagaac acggatagtc aagggtgtgt tagcatttat ttacccttta
     3541 ctatctgggg gcttgctggc actttcctaa atgccagaat acacacatca atcaaactta
     3601 aagtaagaaa cgaggtaaaa taatatggaa ttaaaatata tcgtgccgaa tgtggcacag
     3661 acttttggaa acttggaatt tgcaggggaa aacaaagtag accagcaacg tatcaatggg
     3721 cgttacactc tcgtatcaag aagttacaac ttgtattcgg atattcagag agccgacgac
     3781 attatcgttg tattgcctgc aaaagctggc gagaagcatt ttaagccaga gcagaaagta
     3841 aaactgatta acccacgcat taccgcagag ggttacaacg tcaaaggacg tggatttaca
     3901 aactacattt taatggctga tgatatgtta ccagcagaaa gcaaataagg gggtatttga
     3961 ttatgagatt agcaaatgga attgtattag ataacgaaaa aacttttgga gtattgaaat
     4021 tctctgcact tcgacatgag gtgcgtgtag aaaatgagga cggaacgaca agtgatgaaa
     4081 ttaagcgtcg tacttatgat ttgaaatgta gtgtgcagga acgcatgata caagtgtcaa
     4141 tccccgctga tgttcccgta aaggactttc cttataatgc ggaagtggag ttaatcaatc
     4201 ccgtagctga tacggtggca aatgccaact ttagagggac tacggttgat tggtacatca
     4261 aagctgatga tattgtattg aagaacaaag gcggtcaagc tggaaatccg cagaacaacg
     4321 ctccgcaggg acagcagaaa aagtaagctg acaaactagt ttttcattgt aggagatata
     4381 aacaactgtt ataatatgga tgtggaaaca gttaatttag acttataaag gagaaatgtg
     4441 tatgctagat aaaataccta atgcagagga aatgactgct ttggtcggac aatcattata
     4501 tagtgtatgg aatgaattgt gtgccttgat tgatgaaaag tatgaaatgg aatgtctatg
     4561 gaataaaggt ggcaaagcat ggaattatga atataagtat cgtcgaggtg gcaaaacatt
     4621 atgtgcctta tatgctagag aaaactgtgt gggatttatg attatcttag gtaaagatga
     4681 acggttaaaa ttcgatacat atagagataa ttattcaaaa gaagttcaga gaatttatga
     4741 tgaaacaaaa acttaccatg acggaaaatg gctgatgttt gagccaacag atacaacttt
     4801 gtttgacgat tttgttaaac ttttgaggat aaaaagaaaa ccaaatagaa agtagtttat
     4861 taccacacca ttagcaaatg gatagtttct tataatagcg gatatatgaa aatgctgtca
     4921 tgtggacata aagaaaattg gaagttgtgg aggtagcaaa aatgaaatta aaaaacccta
     4981 tgttggtagt aactgatata gataaatcag ttgggtttta taaaaaggtt tttggacttt
     5041 atgtcattat ggattttggg gcaaataaaa ctttaacagg tggattagcc ttacagacaa
     5101 gtgaaacata caaagagttt atcggtacaa gtgatatttc ttttggtggt aacaattttg
     5161 aagtctattt tgaagaagaa gattttgata aatttgctga taggctgaaa gaatatgata
     5221 ttgaatatgt ccaccctatt atagaacatt catggggaca gcgtgtagtc cgcttttatg
     5281 acccagataa acatattatc gaagttggag aaaacatgaa gatagtgtgc aagcgtttct
     5341 taaatagtgg aatgacacca gaacaagttg cagaacgtat ggatgtacct atgaaattta
     5401 taaatgcttg tatgcgataa attgaaagtt aggagactaa tactatgaaa ggatttgaac
     5461 gcaaaaatca attattttct ctttgcggat tgaattgcgg actatgccct atgcttttgg
     5521 gaaattactg tggcggttgt ggcaatggta atcaatcatg cagaattgca aaatgtagtc
     5581 ttgaacatgg acagattgaa tattgctatg aatgcaaaca atatccatgc gaaaaatatc
     5641 aacacattga tgattatgat tctttcatca cgcataaacg gcgaaaagca gatttagaaa
     5701 gagcaaaaaa cataggcatt gagcaatata atcttgaaca gcaggaaaaa acacaaattc
     5761 tttcttactt actttctaac tataatgacg ggcgtagaaa gactttcttt tgtgtggcag
     5821 tcaatttatt agaactttca gaattacaag aagcaatgaa acaaatacaa tccaatgacg
     5881 aattgacctt actaccattt aaggcacaat gcttgtatgt ggtggaggtg tttcagaaga
     5941 ttgctgaaag gagaaatata aaactgaaac ttttcaagaa aaagtgattt tcaaatttga
     6001 aattgtaaca aagattattt atatgacgaa tgggggaata cctttggaaa cagtagagtt
     6061 aagatttcaa tatactcaaa gtgaatatat aaaagcagaa aggcaatatt taatttctag
     6121 taaaactata cataaatatg atattgcttt agtcgctgta tttttgttgc tgtcagtctt
     6181 ttatatgctg ttctcctctt ttagcgtatt tagtatttta atatttggat tgataattgt
     6241 tgtaactgca ttgggaagct atttatatat cctaatgcct atactgaaat tcaaacaaac
     6301 tgcaaaatat catgaggaat atacgctggt attttctaag gaaaacatta aatttaaaac
     6361 acaaagcatt gactcagaag tgaagtggga catttactct gcactatggg aaagccatga
     6421 tttttattac ttaattcaag caccacgatt atatacgtta attcccaaaa gagtttttaa
     6481 agacctaaac gaaaaacagc tatttgaaga aattgcacaa tcaagagtta aaacaacaaa
     6541 gcatatataa tgaacatacc ctacaatgta acaacttcat attcatacac acaaagcggt
     6601 tagtctttta agattgactg cttttttcat acttaaatta agattggagt gattgattta
     6661 tgcgaatgat tttgaataaa ggacaccgta tcagagccag agacaagaac cttgtctacc
     6721 acttttccat agggacgctt ctgtttgtat ttgtggcggt tctcctgcta ctgaatatca
     6781 aacagctcat gcgtaccgac tgggaacatt tcagcttatt ggacaatggc ttgacgcttt
     6841 ccccctacaa cttcataacc atattgatag cgactggtat ttgtgcattg gtcgcttttc
     6901 tgtattaccg cttctgttat gacagtttca aaaagctcct gcaccgtcaa aagctggcac
     6961 gaatgatact ggaaaacaag tggtatgaag cagataccgt acaagacagc ggttttttta
     7021 ctgacctgca aagcagatca agggaaaaaa tcgtctggtt tccaaagatt tattatcaaa
     7081 tggaaaacgg attgcttcat attcactgtg aaatcacatt aggaaaatat caagaccagc
     7141 ttttgcgatt agaggataag ctggaaagcg gtttgtactg tgagctgacc gacaagacct
     7201 tgcatgacgg ctatattgag tacacgcttt tatatgacat gatagcgaac cgtatttcca
     7261 ttgacgaagt gaaagcagaa aacggctgtc ttaggctgat gaaaaatctt gtctgggaat
     7321 atgacgtact ccctcacgct ctgatagctg gtgggactgg tggcggtaag acctactttc
     7381 tgctgacgct tattgaagct ctgctacata cgaatgctgt cctttacatc ttagacccaa
     7441 agaacgctga ccttgcagac ttaggtacag ttatgggaaa tgtgtatcat accaaagaag
     7501 atatgattga ttgtgtcaat gccttttatg agggcatggt acaaagaagc gaagaaatga
     7561 agcaacaccc agactataaa acgggcgaaa actacgccta tcttggttta ccgccctgct
     7621 ttcttatctt tgatgaatat gtggcgtttt ttgaaatgct ggggacaaag gaaagcgtaa
     7681 gtttacttag ccagttaaag aaaatcgtta tgttgggacg acaagctgga tatttcctta
     7741 ttgttgcctg ccagcgtcca gacgcaaaat atttctcgga cggtatcaga gataatttca
     7801 atttccgtgt tggattgggg cgtatcagcg aattgggtta cggtatgctc tttggttctg
     7861 atgtgaaaaa acagtttttc cagaagcgta tcaaggggcg tggctattgt gatgtgggaa
     7921 caagtgtcat aagtgagttt tacacgcctt tagtcccgaa aggacatgat tttttgcaga
     7981 ccataggctc tcttgcattc gtaaggcagg acgggacggc gacgtgcgaa gcgaaaggcg
     8041 acggcacgga ctagccgttg ctggtgtggc gttagccacg ccagcagata taagcccctc
     8101 attatctaac agaggggcac aattacgctg gaaactggct caaaaacctt gaaaagtccg
     8161 ctaggaataa ggattttctt agtttttagc tagttgtgat aatcacttga aaatatcaca
     8221 aaatcacaac aatatcacga ttgggggtat gacaactgaa tgatactgat tttctgaaca
     8281 ccttgaaagc aaaacgcagt gattatggcg tatcgcagac aaggcttgca atcatggctg
     8341 gtatcagccg tgaacatcta agccgtatcg aagctgggaa ggtagcactg accgaggata
     8401 tgaagcacaa actactggaa gcggtggaaa aattcaatcc cgacgctccc atgttcctgc
     8461 tctttgatta tgtgcgtatc cgatttccca cgctggatat acagcacgtt atcaaggaca
     8521 ttctaaagct gaatatagat tatatgcttc acgaagattt cgggcattac aagtacaccg
     8581 agcattacta tatcggggac gtgttcgttt acacttcaca agacaaggaa aaaggtgtcc
     8641 tgctggaact gaaaggaaaa ggctgtcgtc agtttgaaag ctatctgctg gcacaggaaa
     8701 gaagctggta tgacttcctc atggacgcat tagttgatgg cggtgtgatg aagcgtatcg
     8761 acctagctat caacgacaga acgggcttac tggatattcc agaactgata gagaaatgca
     8821 agaacgagga atgtatttct aaattccgta gcttcaagaa ctatggttct ggggagctgg
     8881 taaaacacaa cgaagccaac aaggacggca tgggacatac gctttacatt ggttcattta
     8941 ccagtgaagt gtacttctgt gtctatgaaa agaattatga acaatcctca aaattaggga
     9001 taccgattga ggaagtcccc attaaaaacc gatttgagat acgtttgaaa aatgagcacg
     9061 cctactatgc cgttagagaa ctgctgaccc actacgacgc agagctgacg gcattttcta
     9121 ttatcaacca gtatatccgc tttgccgata aggaagccaa caagcgaaaa agcgactgga
     9181 aaaccaacgc ccgctggtct tgattcattg gcgagggacg accgcccgtg aagctgacga
     9241 caaagccaga gccttacact ctgcaaagga cgctgaactg gttacaaaga caggttgcac
     9301 cgaccttgaa aatgctgaaa cagatagacg ctggcaatca gatggactat ctcaagacca
     9361 ttgaacagca ggcaaagctg acagataagc acaagcagat aatcagacag cagacggctt
     9421 cggtggacga actgatagaa aaagaaaagg agtgattgat gatgtgggaa ttgattaagg
     9481 acttactgct ggtatcactt ggcatgggta tcggcgtggt tctgatgtgt attatgagtg
     9541 tcggaaagga agctgaccga cacatgattg aattaaaaga aagcgaggaa aaataaatga
     9601 atttcgggca aaatttatat acatggtttt taagcaacgc ccagagctta gtgcttatgg
     9661 cgattgtggt tattggtatc tacttagggt ttaaacgtga gttttcaaaa cttatcggct
     9721 tcttggtggt tgccttagtt gctgttggat tggtattcaa tacaggcggt gtcaaagacg
     9781 tactcttaga actattcaat aagattatcg gcgcatagcc gtactttttc attatggttt
     9841 gcggatacgc aaacatacct ttcccacttt gggagtgggc taaggggaaa aggggtaacg
     9901 gaatggtaca cagataaaaa tacagcataa tgaatttcat tgcttggctc aaacatagtt
     9961 gatataataa agatatgaaa ataataaacg aaagtttttt tgataaggag tgatattgtg
    10021 aaattgtgta ttgttttatc tccatataag gcttaatgga atagacttgt atggagtgaa
    10081 atgttatcca gagagcctta cattttatca aatttcaaaa tgtaaaggag aatgggcatg
    10141 gaatataaat atacaaaaat tgatttgaat aaatggaata gaggtaaatt gtttcaaagc
    10201 tacattgata atatgcgtat tgttatgagc ttaaccgtag atattgatgt aacaaagttt
    10261 attgaatttt caaagaagca tgatttaaaa ttttatccag ctatgatatg ggctgtttca
    10321 aaggttgtta atgaacatga tgagttcaaa tatagttggg ataataatgg gaatttaatt
    10381 aagtgggatt atatttctcc gtcctatact gaatttcata aagaagatga aaatttcaca
    10441 aagatagtta cagatttttc tgatagcata tttgaatttc ataaacgttt tatattagat
    10501 agggagaagt ataaaacaga acgtgcattt gtggaaaatc aatctttgaa cttttttgat
    10561 gtatcttgtt taccgtgggt aaaatataat cattttgatg ttcatgtttt tgacgaggga
    10621 aaatttcttg caccagttat tacttggggc aaatatgaat tagagcaaga aagatatata
    10681 atgcctctta caatgaatat acatcatgcc gtagcagatg gattccattt atccagattt
    10741 tttaatgaag tacaagaatt gataaactca atttaacagc tatatatcag atatatacaa
    10801 agcagttagt ctatacgatt gactgctttt tttcatacct aaatttaaga ttggagtgat
    10861 tgcttgaaag atatattttc ggatatgcag gcaagtatcg gctgtaccta catttcagat
    10921 ttaccacatc ataaacgtat ggtgtggcag gaaatgaagc gactgaacct tgccgattat
    10981 ccgcagaaac aattagaaga ttttgcaggc tatgtctttg gtgtccctta cactagcata
    11041 gctgaagcat gaaagaaagg acgtgaaaac ctatgaatga aatgcgtgtc tgtatcgaaa
    11101 gccgactaca cacttctgaa gaaatccgtt ccgcatggtt cacacttccc attgacgagg
    11161 aagaactgga agaacagata ggcgttccta tcgacagtga agattaccat atcgttgaaa
    11221 aggaactgcc ctttgctgat gaagtcggcg aagatgcgac cattgaaaaa ctgaatgacc
    11281 tttaccatac ctttgaaagt ctgcctgccg atttacaaga ggactacggg gagctgatgt
    11341 gttactttac cagccttgac gaactgcacc agcaccgcca tgatgtgata cattattcat
    11401 ggtgtaaaaa catggctgat gtggcaaggc atttgttgga caatgaccct gctttttctg
    11461 ccattgagga acgcctgacc cgttactttg attatgaagc ctacggacag tatcttgatg
    11521 ataacggaaa atttatagaa acagaccacg gtatctatga actgccgtag aagtgaggtg
    11581 tttctatggt agaggatatg cgtgtatata tcgctaatct tgggaaatac aatgaggggt
    11641 atctggtcgg cgactggttc tcttttccga ttgacgaaga agatgttgcc gagcgtatcg
    11701 gcttgaatga acggtacgaa gaatacgccg tacatgatac ggaaaacttt cccattgaga
    11761 ttggcgaata tatctcgatt gaagaactca atgaaatgta tgaaatgata tgtgagcttc
    11821 ccgactacat cacggacagt ttggacgaat ttgtatcaaa ttatggaagt ttggaggaac
    11881 tgtgcgacca tagggacgat atgattttat acgctggctg tgaggatatg accgacgttg
    11941 cctattactt cattgatgaa ttgcaggcac ttggcgatat tccccctagt ttgcagaact
    12001 atattgacta tgaagcatac ggcagggatt tatcctttga gggaactttt attgaaacaa
    12061 gatacggtat gtgtgagata ccgtggtaag aagctggaag atcagcgaca agcattgttg
    12121 cttctgacag ctttttctat tggggacagt ctgaaaaacg gctgtccttt tctattatac
    12181 gaaaggagtt gaaacaaaaa cgtgaaaaag attaaaagct acacgggtat ctggaacgtg
    12241 gaaaaagtct tgtatgcaat caatgacttt aacctgccct ttcctgttac ctttacacag
    12301 attacatggt ttgtgataac cgagtttatc atcattctgt ttggggactt accgccctta
    12361 tccatgattg agggggcatt tttaaaatac ttcggtattc ccgtagctct cacatggttc
    12421 atgtcgcaaa agatctttga cggcaagaag ccgtacagct ttttgaaatc acagataacc
    12481 tttgccctac gaccaaagat tacttatgca ggaaaagccg tgaaactgga taagcaggta
    12541 ctacatgaag ctattacggc agtaaggagt gtgagctatg ttcccgatta aatatatcga
    12601 caacaacctt gtctggaaca aggacaatga ggtgttcgcc tactatgagc tgatacctta
    12661 caattacagt tttctatccg ctgaacagaa attcattgtg catgacagct tccgacagct
    12721 aatcgcacaa tcccgtgagg gcaagataca cgctttgcag attgccacag aaagctcaag
    12781 ccgaagcata caagaacagt caaagaagct ggttacggga cgactaaaag acgttgccta
    12841 tcagaagata gacgaacaga ccgaagcgtt agtatctatg attggggaca atcaagtgga
    12901 ctaccgcttt tttcttggct tcaagctcat ggtaacagac cagagcatga acctaaagag
    12961 cgtgaagcaa tcggcgtttc tcacattcaa ggagtttatc catgaagtga accacacgct
    13021 gatgaatgac tttgtttcca tgccaaatga tgaaatcaac cgctacatga aaatggaaaa
    13081 gctgttggaa aataaaatca gccgacgctt caaagtaaga cgcttagata aaaatgactt
    13141 cggctatctg attgaacaca tctacggcag ggacggtgtc gcctatgaag attatgagta
    13201 tagcttaccg aagaagaaac tgaaaaagga aacgctgata acgcattatg acttgatacg
    13261 tccgacccgt tgccttgtgg aagaaagcca gcgacattta cgcttggaac atgaggacag
    13321 cgaaagctac gtttcctact ttactgtcaa tgcgattgtc ggcgagcttg attttccgtc
    13381 cagtgaaatc ttctatttcc agcaacagca gtttactttt cccgttgata ccagcatgaa
    13441 tgtagaaatc gtggaaaacc gaaaagcgtt atcgacggtt cgcaacaaga aaaaagagct
    13501 gaaagattta gacaatcatg cataccagtc tggcagtgaa accagctcaa atgtggtaga
    13561 cgcattagac agtgtggacg agctggaaac ggatttagac cagtccaaag aaagtatgta
    13621 taagctctct tatgttatcc gtgtatctgc tccagacctt gacgagttga aaagacgctg
    13681 tgatgaagtc aaagacttct acgacgattt gaacgtcaag ctggtacgcc ctgctggcga
    13741 tatgctgggg cttcactctg aatttcttcc tgccagcaag cgatacatca acgattatgt
    13801 gcagtatgtc aaaagtgatt ttctagctgg gctgggcttt ggtgcgacac agcagttagg
    13861 ggaaaacacg ggtatctata tcggctattc tgtcgatacg ggacgcaatg tttatctaca
    13921 accgtccctt gccagtcaag gcgtaaaagg tacggttact aatgctcttg cttctgcctt
    13981 tgtaggaagt cttggcggtg gaaaatcatt ctgtaacaac ctgcttgtct actactctgt
    14041 gctgtttggc ggtcaagcgg taatcttaga cccaaaatcc gagcgtggca actggaaaga
    14101 aacgctccca gaaatcgccc atgaaatcaa tatcgtgaac cttaccagcg acagagaaaa
    14161 tgcagggctt cttgacccgt tcgtgattat gcagaatgtg aaagacgctg aaagtctggc
    14221 aatcgacata ctcacattcc ttacgggcat ttcttcaagg gacggcgaga agttccccgt
    14281 acttagaaag gcagtgcgtg ccgttaccca gagcgaccag cgaggattgc tccatgtgat
    14341 tgaggaatta agaaaagaag atacacctat ctcttgcaat attgccgacc atatcgacag
    14401 cttcacggac tacgactttg cacatctgct gttctcggac ggtacggtgc aaaatgcaat
    14461 cagcttagac aaccagctca atatcattca agtagccgac ttagtgctac ccgataagga
    14521 cacgaccttt gaggaataca cgaccattga attactgtcc gtttccatgc tgattgtgat
    14581 tagtaccttt gcgttagatt ttatccactc ggatagaagt gttttcaaga ttgtagacct
    14641 tgacgaagca tgggcgttct taaatgtggc acaaggcgaa acgctctcta acaagctggt
    14701 tcgtgctgga cgtgccatga acgcaggcgt ttattttgtt acacagtcct ctggcgacgt
    14761 gtcaaaggaa agtctgaaaa acaatatcgg tttgaaatct gcctttagaa gcaccgatat
    14821 taacgaaata aaacagaccc ttgaattttt cagcattgac aaagaggacg agaacaacca
    14881 gaagcgattg cgtgatttgg aaaacgggca atgcttgctt caagatttat acggacgtgt
    14941 gggcgtggtg cagatacacc cagtctttga agaattactg cacgcctttg ataccagacc
    15001 gccgatacag cgaaatgagg tggagtgatg aaagaaagga taaaaagtgt gttcacaaga
    15061 aaaaagatat tccgctttct caaaatggct ctgtttgtcg tggcactttc ccttatcctg
    15121 ctttcacttt tgggaacggt ggcacacgca acgggacttg tggacgacac tatcaacacc
    15181 gagaaccttt attccaaata tccgctgtcg aattatcagc ttgatttcta tgcatataat
    15241 aactgggcgt ggttgccgtg gaactggctg gacgggattg gaaaaagtgt gcaatatggg
    15301 ctttactgta ttaccaactt tgtctggacg ataagcctat atctaagcaa tgcaacgggc
    15361 tatgtagtgc aggaagccta caagctggac tttatcaacg atatggcaga cagtatcgga
    15421 aaaagcatac agacccttgc aggcgtaatt caaaatggtt tttctacttc gggcttttat
    15481 gtgggatttc ttctgctgat tatcttagtc gtaggtatct atgttgccta tacgggactg
    15541 ataaaacggg aaaccagtgg cactacacgc cgttatcaac tttgttgtgg tgttcgtatt
    15601 atcggcttct tttatcgcct atgctcctga ctacatcaag aaagtgaatg acttttcatc
    15661 agacatcagt accgcttcac tggacttggg aacaaaaatc atgcttcccg acagcgacag
    15721 caagggcaag gacagcgtgg acttgataag ggatagccta ttttccatac aagtacaaca
    15781 gccgtggcta ctgcttcaat ttggtaattc ggatatagag gaaatcgagg cagaccgtgt
    15841 cgaagctctc gtatcggcaa gcccagagga cgaggacggc aagaccagag aggaagtcgt
    15901 gaaaacagaa atcgaggaca acgacaacaa caatctgacg ataccgcaag tggtaaaccg
    15961 tttaggtatg gtgttcttcc tcttgttctt caacttgggt atcacgatat ttgtattctt
    16021 gcttacgggt atgatgttgt tcagccagat actttttatc attttcgcta tgtttctgcc
    16081 tatcagcttt ctattaagta tgataccgag ctatgagagc atggcaaaac aagccatagt
    16141 ccgtgtgttt aatacgatta tgacaagggc aggtattaca ctgattgtca cggtagcctt
    16201 tagtatttcc agtatgttct acaacatatc gacggactac ccgttcttta tggtggcgtt
    16261 cttgcagata gtgtgttttg caagtatcta catgaagctg ggcgatttaa tgagtatgtt
    16321 ctctttaaac gctggcgaca gtcaaagcat gggacggcga atattccgca gaccgtatct
    16381 gttcatgcga catagggcta gacgtatgga acataggctt gcaagagctg ttagtgctgg
    16441 tggtgtcgct ggtgcggtgg ctggtggtgt cgttgccagt tcaaaatcta cacgccagaa
    16501 tggaacaaag aacaatcgtg gaaatacaag ctccagcatg gggcagaaag caggttcagc
    16561 cgtgggagct gtccttgata caaagaataa ggtcaaggac aaggcaactg ctgtcaaaga
    16621 aaatatcaaa gatatgccga cacagactgc ctatgcggtt cactctgcta aggaaaaggc
    16681 gacgtccagt gtgtctgatt tcaagcgtgg cgtggtgcag gaaaaggaaa accgccagtc
    16741 tggacgctta aagaagcaac agctacatag acagaatatc gctgacaagc gtatggaact
    16801 tcaaaaggca caagaagcaa ggcaggcagg taagaaaacg gacggatcag cgacaagcgg
    16861 agctacccgt ccccatgaaa gaccagctac cacttctaag gttaatgtag aaaaacagca
    16921 ggaagtcaaa cgccctgcca tagcttcaac cgtgaagaat gatgaaccta tcaagaaaaa
    16981 tgttgtcaag gaacgtccac tatcttctgg cgatacatca gcaaagaccg tcaatcaaga
    17041 aaccacaaga cagaattaca agactgaccg tgttacgaaa acaaccgttc agaagcatac
    17101 acagcagaat accgagaaga acaaacgaac cgtattcaag aaaggacaaa agaagaaatg
    17161 aaactaagac atatcgctat tgttggcagt ctgttttcta tcctcttttc tctcgtatta
    17221 ttctttgggg ttctgattag tgccgaggac gacgacgggg gcaatggtta ttcctctaat
    17281 tatgtaggta tgaacctatc tgccgaagtc ttgaaacatc agcctatggt agaaaagtat
    17341 gccaaagaaa acggtatttc cgagtatgtc aatgtgttgc tggtaatcat acaagtggaa
    17401 agtggcggta cagccgagga cgttatgcaa agctctgaaa gtctgggact accacccaac
    17461 tcactagata cggaaagctc aatcaagcag gggtgtaaat attttgcgtc cctgctttct
    17521 tcctgcaaaa atcaaggtat cagtgatata aatgttgtga tacagtccta taactatggc
    17581 ggtggctatg ttggctatgt ggcaggaaac ggaaaaaagc atatgttcaa ccttgcggaa
    17641 aacttcgcaa gggataagtc gggcggtcaa aaagtaacct atacgaaccc tatcgccgtg
    17701 gcaaaaaatg gtggctggcg ttatggctat ggaaatatgt tctatgtgga gcttgtgaac
    17761 cagtaccttg ttgtcaatca agtatcgggc gagctggcac aaaaggttat gaatgaagcc
    17821 ttaaaatatc aaggttggaa gtatgtatat ggtggcagta acccgaacac ttcttttgat
    17881 tgttcgggac tggtacagtg gtgctacaac aaagctggcg tatctttacc gagaaccgca
    17941 caaaatcagt atgacgcaac ccagcatatc ccactatcgc aggcaaaggc aggcgatttg
    18001 gtctttttcc acagtaccta caatgcagga agctatgtaa cccacgtcgg tatctatgta
    18061 ggaaacactc agatgtatca tgcaggcgac cctatcggat atgccgattt aaacaatgct
    18121 tattggcaac agcacttgat ttgtgctgga agaataaaac agtagaaagg attggaaacc
    18181 atgtttaaaa agaaagaaaa accagtaaaa gaaacgaaag tccgcactat gaaagtaggc
    18241 acacataaga aatctgtgat tgctctgtgg gtggtgctta tcgccagcgt atcatttggc
    18301 gtgtataaga actttaccgc cattgatatg cacacggtac atgaaacgga aaccattcag
    18361 ttaagactaa atgacaccaa cggagttgaa aattttgtga agaacttctg taagtcctac
    18421 tacacatggg acaacagcaa ggaagctatc gaagcaagga cgcaggcaat cagcaactat
    18481 ctgacaaagg agttgcagga cttgaacctt gataccatta ggacggatat accgacaagc
    18541 tccactgtta caaatgtact gatttgggat ataaaacagt ctggaacgaa cgattttatc
    18601 gctacctacg aagtagatca gcagataaaa gagggagaac agacaagcaa tgtcaaagca
    18661 acctataccg tcaaagtcca tgtggataaa gacggcgata tggttatcgt acagaaccca
    18721 accattgcac cagcgattga aaaatcagac tatgagccaa aggcacaaga agccgacgca
    18781 agcgtggacg cagataccgt caatgacgct accgcatttt tggaaacttt ctttaagctg
    18841 tatccgacag caacagaaaa agaacttgct tactatgtag ctggcaatgt gcttgaacct
    18901 atcggcaagg actacctcta ttcagaatta gtcaatcccg tgtttacggc tgacggcgac
    18961 aatgtgaaag tcaaggttgc cgtgagattc attgataatc agacaaaggc aacgcaggta
    19021 tcacagtttg agcttatgct acataaggat agtaactgga aaattattat gtaagatatt
    19081 ttgttggcag gctctatttt cggatatagt ctgccttttc tgtagcaaat gtgctgcact
    19141 aacaagcgat ttcattgtat tttaagcaat taaatctttc ttgacaattt tatcttaaat
    19201 catatattta tggatattga ctttctgctt acaataagtt ataatatgac tataaaacca
    19261 aattagtcac atgggaggta tgtggtatgt ataaagaagt tggtatttct tcaaataatg
    19321 ttccgataac actttctatc tggtatacag aaagaagtag tcctaccatt gtttttttgc
    19381 cgggtactat gtcacaccct ctcatgtatg agaattttct atgtggtttg agtgaaagag
    19441 gatttaatat aataggcatt cactatcttt cacacggaaa aagccctaaa atcaaaaaaa
    19501 attatacaat ggaagatttg ctgcataatg tatatgacgc aacaacttac ggaatagaaa
    19561 attttggtga aaacatagct gtcatgggtt ccagtcaagg cgggatttta gctgcaatgg
    19621 cggcgggtag ggacacaagg ttaaaagccg tttttccaca taatatcatg ctgactacat
    19681 taaaagaaac tatgagctta acaaaatatc ccgcatggtc acaccgtttt atggggctga
    19741 tacagttggg ctttcgtgta ggtggaaaat tgctgcctaa ctataaggtt ccaggagacg
    19801 cttatttaga ctatgacaga gtattttata gtgaacaggc aaaacaagat tgcttaaatg
    19861 accctatgct tttaccctat tatcctttaa gatttgtcgc cagcttattt aatgctgact
    19921 tatcgtgctt ggagaatggg gctatacaat gtcctgttat tttaattact gctaaaggcg
    19981 atccgctttt tagctttgat tataccaaca aagtatttga tttaattcat gtaccgaaaa
    20041 aggaattact tactttagag cttaatcgtc acatgatttt taatgaggac acggacacta
    20101 caataaacgc attggaacct acattgcata aatatcttgg atagtatatt gattatataa
    20161 tcagtaaatg ttatactttc catgacgata aaaacatttt agtcataagg gggttatgag
    20221 tttgccacga tttacggaac aagagaaaga gatcatcagc agtaaacttt tgatagaggg
    20281 agaaaagctg tttgcattac acggtttgaa aaaagtaacg gttgatgatt tagtagccgc
    20341 cgtaaacata tcaaaaggtt ctttctatgc tttttatccc agtaaagaac atctatacgt
    20401 ggacatcaat tttcgcttac aaaaagagtt atttacaagt atagaaacaa ccgttaaaaa
    20461 gaaaaagtat aagaaccata gagatttagc aaaggacgtt attatgctaa gtttaacggg
    20521 ggtgattact tcgcctattc tttcacagat tgatttatct ttaatggact atctgcaaag
    20581 aaaaatatcg tcagatattt ttgaaaatca tatgtacagt gatattagta tattggagat
    20641 actggaaggt ttaggggttg tatttttggt tccgcatacg gttatcataa aatccctgta
    20701 ctctgtttta tcctgttt
//
LOCUS       DACTZW010000076        20500 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.076, whole genome shotgun sequence.
ACCESSION   DACTZW010000076 DACTZW010000000
VERSION     DACTZW010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20500
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.076"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(556..996)
                     /locus_tag="JAM15_14365"
     CDS             complement(556..996)
                     /locus_tag="JAM15_14365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufBD protein"
                     /protein_id="HAT6799437.1"
                     /translation="MENLNLLINKLYSKNHNEAYKTFLFLENESLKSNITYCFFDSFL
                     EMIDNENSYIRTRGLLLISANAQWDIDNKIEINIDSILSHITDKKPSVSRMFIKSIPN
                     ITKYKKNLINLIKMELSNADISIYNNNMKPLVEKDISDTLSNLS"
     gene            complement(1202..1579)
                     /locus_tag="JAM15_14370"
     CDS             complement(1202..1579)
                     /locus_tag="JAM15_14370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monooxygenase"
                     /protein_id="HAT6799438.1"
                     /translation="MCDKVIASKYHEKGFNCAESVIKAYNEEFNTDIPVCLGSGLGSG
                     CGVASLCGAVNASNIIIGYVKGRNHEDESTKAKVYAKDLTTTVRKEYGSELCIDLKKD
                     LVACREIMDFAYDSLKETLKKEL"
     gene            complement(1695..2189)
                     /locus_tag="JAM15_14375"
     CDS             complement(1695..2189)
                     /locus_tag="JAM15_14375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HAT6799439.1"
                     /translation="MSLVYDVYKSKLGNLYILSEDGFIVSVYIGDEKFNNLKNECIKK
                     GIDIKRSKEDLKEAISQIDDYFNGKRKVFNLNIRIEGTEFQKSVYREMLKIPYGETLC
                     YSDIARNINNPKSVRAIGQASKSNKIPIIVPCHRVVGKKDIGGYMGNHSDLKEILLNL
                     ERQS"
     gene            complement(2338..6591)
                     /locus_tag="JAM15_14380"
     CDS             complement(2338..6591)
                     /locus_tag="JAM15_14380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HAT6799440.1"
                     /translation="MDELFHIGIDVGSTTVKVVVLNNSNNIVHKEYRRHYSDVKKSVK
                     EVLNGIYEKLGDINTTIIITGSGGIGISKKLGVKFVQEVISSTKSIEYFHPETDVVIE
                     LGGEDAKITYLSGGIDQRMNGICAGGTGAFIDQMASLLKTDASGLNELAKGYNVIYPI
                     ASRCGVFAKTDIQPLINDGANQTDIAMSIFNAVVVQTVSVLSCGRKIEGNVAFLGGPL
                     YFLSELREAFKRVLDLKDENIIFPENAQLYIAIGAGLLSVDEDNIQLKSLIEKLDSIK
                     NIEDGEVNLLEPLFKDKNEYEEFSRRHEKEKISYVDINSIKSNCYLGIDAGSTTTKAA
                     LIDEDGRLVYSYYNSNEGNPLKTTIKVINEVYDILPKNIKILSSTVTGYGEGLIKKAL
                     KIDNGEIETIAHYKAAKFFNKDVDFILDIGGQDMKCLKIKDGVIDNIILNEACSSGCG
                     SFLETFASSLSMTIEEFAHEGIYSQNPVDLGSRCTVFMNSRVKQAQKEGASVGDISAG
                     LSYSVIKNALFKVIKIRDLNEIGNNIVVQGGTFYNDLVLRSFEKLIGKNVIRPNISGI
                     MGAFGSALIAKEKYESGYKTSLLSKEELNNIKLEASVTRCKGCSNHCLLTINKFSDNE
                     IFISGNRCEKGEAIYGDKKIGLEKKKPINLFKYKYNRIFRYKPLEKEEAKNGEIGIPR
                     VLNMYEDYPFWFTFFNAMGFRVVLSDRSSKQLYETGITSIASETVCYPGKLVHGHIEN
                     LIAKGIKNIFYPSVTNENKEDSNADNYYNCPVVISYSEVIKNNVENIRNKNINYINPF
                     ISLNDKEKLKKRLYDELSRHFSDIKITKEEVNHAVDKATDEQNLFKMEIQAAGERALK
                     EIKERNMKGIVLCGRPYHIDPEINHGMPELINSLDMAVLTEDSICHLANVQRPLRVVD
                     QWVYHSRLYKAASFVRDKNYLELVQLNSFGCGLDAVTTDQVQEILNEKSKIYTIIKID
                     EGNNLGAAKIRMRSLKAAMFERESKNIDVKNIKVNRIQYAKNNQITNKHTILAPQMSP
                     IHFQFLEKAVNLSGYNIEILKDTDSSVIEEGLRYVNNDACYPAIIVVGQLITALKSGK
                     YDLNNTSVTITQTGGGCRATNYIGFLRKAIYDAGFKDVPVIALSVNGIEDSGIMDNIS
                     LKLINRLFMSVVYGDLLMKVLYRVRPYEKVTGSANALYEKWVDICKTSLVKAKISVFT
                     RNIKDIVKEFDNLEILDVKKPKVGLVGEILVKFHPIANNNLVDILEREGAEAVVPDLT
                     NFFLSCAFNTIYKHTHLEGSRKSRMIGEAFIYITGIYQRVYKKALDKSERFYAPANIK
                     NVAKSTEPVVSLGNQTGEGWLLTGEMVELLNEGVENIICMQPFGCLPNHIIGKGSIKE
                     LKRLYKNANIIPIDYDPSASEVNQLNRIKLMLSKAFKNI"
     gene            complement(6972..8141)
                     /locus_tag="JAM15_14385"
     CDS             complement(6972..8141)
                     /locus_tag="JAM15_14385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799441.1"
                     /translation="MEKLTDRRQVKAVSMETFIFLILLVVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLETVFLIMAMAVLAGALSALLSEFGVIALINKIFAVFMKPLYGLPGASIA
                     GAITTYLSDNPAIIPFAKDKTFTQYFKQYQVPALCNLGTAFGMGLILTTFMISQGTEY
                     VLPALIGNLGAIIGSVISVRIMLTFTKKFYKYNPEEDKATGTLEKKDEFREIREGNVF
                     QRALDAILEGGKMGVDMGMAIIPGVLVVCTLVMLLTFGPSTDPVTGQEVYTGAAYEGI
                     KLLPVIGDKLGFILEPLFGFTSPEAIAFPITSLGAVGAAMSLVPEFIKSGAITPNDIA
                     VFTAMGMCWSGYLSTHIGMMDALNARQLAGKAILSHTIGGLCAGAAAHFIFTLVG"
     gene            complement(8535..9551)
                     /gene="gap"
                     /locus_tag="JAM15_14390"
     CDS             complement(8535..9551)
                     /gene="gap"
                     /locus_tag="JAM15_14390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007063445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HAT6799442.1"
                     /translation="MKIKVGMNGFGRIGRAVLRIAQEELGDNIEIVAINARATTESLA
                     HLFTYDSCYGTFRGEVEAKDEDTLVVNSKEIKILRYNDPEELPWKELGVDIVIESTGL
                     FTQREKAAKHIKAGAKKVIITAPGKNEDITIVIGVNEKEYDNEKHNIISNASCTTNCL
                     APFAKVLDEKFGIVKGLMTTVHSYTNDQRILDKSHKDLRRARAAAESIIPTTTGAAKA
                     VSRVLPQLEGKLNGFSLRVPTPTVSLVDLVCELKENVTSEQVNSVLKGAAEGELKGVL
                     GYCDKPLVSIDYKGDSRSSIIDALSTMVIEDNMVKVVSWYDNEWGYSSRTVDLVKYVA
                     EKLK"
     gene            complement(10187..10651)
                     /locus_tag="JAM15_14395"
     CDS             complement(10187..10651)
                     /locus_tag="JAM15_14395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4624 domain-containing lipoprotein"
                     /protein_id="HAT6799443.1"
                     /translation="MKKLVIILISIISVVSLTACKKSNESKYNNLNNKESGQTTIEMD
                     LDKNYDTSDPFVNARLFCVSNDIDVLDTEISFKMDGDSGIVEIKDNKTDETLWSNTWH
                     GSVDNDTFTISLSNIQKEKEYAICFTGIKINHAVVKVTFESNLVKEKEKPSK"
     gene            complement(10975..11583)
                     /locus_tag="JAM15_14400"
     CDS             complement(10975..11583)
                     /locus_tag="JAM15_14400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HAT6799444.1"
                     /translation="MKKTIIKNVNPMIENKFIGLFEIEYKNKLDEDKVWMVASRKSSE
                     QLKNIYLKNEEDSVDAVVIVGLHKSSKKLILIRQFRVPINGYIYELPAGLVDEGESID
                     ISVERELREETGLTLLEIKKNKSIDKVYLSPGMSDESVAFVYCICDGDITDEFLEPDE
                     EIEALLISQEDAKEILQSNHKMDTKAFLILQMFVSLGAKLFE"
     gene            complement(11665..12366)
                     /locus_tag="JAM15_14405"
     CDS             complement(11665..12366)
                     /locus_tag="JAM15_14405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799445.1"
                     /translation="MKFIVEKEVFDKLENVCFGVVVAKGIDNTKEIERISNLLDISID
                     RVEDYFKDKKVKESEEIIPYREAFRSLGMNPNKFMSSIEAMTTRVAKNKKLPHINPIV
                     DLGNSISLKYLLPMGAHDMDFRNDDVYVRFSKKGDKFVPFGETDVELMEEGELIYSVG
                     DMVKTRRWIWRQGEEGKITNSSKNIFFPIDGFTDANLDKVMSAREELAKLLKEIFNCE
                     IKVGFVDKDNPEMEI"
     gene            12593..12859
                     /locus_tag="JAM15_14410"
     CDS             12593..12859
                     /locus_tag="JAM15_14410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HAT6799446.1"
                     /translation="MKNFILIYFIVINSIAFFSMYIDKKRAIRNEWRIKEATLMSIAV
                     IGGSIGSMIGMYSFRHKTKHIKFTFGIPFILFLQFLLVYFYILK"
     gene            complement(12962..13381)
                     /locus_tag="JAM15_14415"
     CDS             complement(12962..13381)
                     /locus_tag="JAM15_14415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjdF family protein"
                     /protein_id="HAT6799447.1"
                     /translation="MDKISGKLTVLFEEPFWVGIFERQDGKKYEACRVVFGAEPKEVE
                     VYEFILERFFSLDFGSIKLEKNVTKDKIGYKRMQRKVKKEQEKETIGTKAQNALNLQY
                     EERKQDRKNLAKNRKEEEKERLFNLKQEKRKAKHKGH"
     gene            complement(13648..14430)
                     /locus_tag="JAM15_14420"
                     /pseudo
     CDS             complement(13648..14430)
                     /locus_tag="JAM15_14420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430254.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
     gene            complement(14495..15256)
                     /locus_tag="JAM15_14425"
     CDS             complement(14495..15256)
                     /locus_tag="JAM15_14425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur protein"
                     /protein_id="HAT6799448.1"
                     /translation="MIGIYFSGTGNSRYCVEKFLQEYDITANSYSIEDNELLQHINNH
                     ENIIFSYPVQYSNVPKILKDFIINHSTLWNGKRVFIIATMALFSGDGSGVLSRILKKY
                     GAITVGGLHVKMPDSIGDEKVLKHSLEYNKKLVIKAEKKVTKAAKKLKHGSPPKEGLG
                     FLSHIVGLFGQRLYFINKTNMYTDKLKINTEECIVCGKCVNLCPMKNLVIKNCMIVAN
                     GQCTMCYRCVNNCAKKAITLLGKKVVEQSNIKKYM"
     gene            complement(15761..15895)
                     /locus_tag="JAM15_14430"
     CDS             complement(15761..15895)
                     /locus_tag="JAM15_14430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RtcB family protein"
                     /protein_id="HAT6799449.1"
                     /translation="MDLINTIDKVQQAHKPIDEIIKTTRDIVDIIKILEPIYNFKSNQ
                     "
     gene            complement(16305..17135)
                     /locus_tag="JAM15_14435"
     CDS             complement(16305..17135)
                     /locus_tag="JAM15_14435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAT6799450.1"
                     /translation="MLNKLCMYLERPELYKQSEINFWDDEYISKQLLKAHLDTNFEGA
                     SRNFNFIEDSVNWIVTVANPVNYPKLLDLGCGPGLYAEKFAQKGYKVTGIDFSKRSIN
                     YAQNRNKETNLNINYLFQSYLNMNYNEEFDLSTLIYCDYGALSTENRRLLMEKIYDSL
                     KPGGKLILDVFTINKYNNFEEIKYWEINEDGGFWSNEKYMCLQDNCKYNDYNTLEQTL
                     VITEKDENVFYVWNHYFSKESFLLEVENIGFKSIEFFSNVKGEAYSDDSMTMGLVLQK
                     "
     gene            complement(17488..18390)
                     /locus_tag="JAM15_14440"
     CDS             complement(17488..18390)
                     /locus_tag="JAM15_14440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HAT6799451.1"
                     /translation="MYNKIKYIPINCEIACNKLKRSMPYKWDLNIYRGCEHGCKYCYA
                     IYSHKYINSNNYFEEIYVKTNIVEKLERQLKSSKWKKEVINIGGVTDSYQPIEADYKI
                     MPEILNLLIKYKTPAIISTKSDLILRDYDLIDKLSRITYINVASTITTVNEDTQRLIE
                     PNGVDSMRRFKMLKEFRKTNASVGLHIMPIIPYITDDFDNINSLFRHAKECNVHYVLP
                     GTLYLRGITRGVFFDFVKKELPELFDKLSILYSAGSLNREYKNQLYKMVNELRYKYSL
                     SSSYSKIMKEKLKNSGDVQISFFD"
     gene            complement(18440..18901)
                     /locus_tag="JAM15_14445"
     CDS             complement(18440..18901)
                     /locus_tag="JAM15_14445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799452.1"
                     /translation="MRLWHKDLIDVLPKNQLVSQWRELLAIKGSIDKKGTPNHLLVNK
                     VLNYSIDEFKFYTKIVHDEMLKRNYKPNELKYTSILKWKNRNFANDISNEHSLNLENL
                     YDDWHNKMYLKQCLYNLEEKATCGGIPINEWNILLCKYSKDYELWSGNIMF"
     gene            complement(18953..19408)
                     /gene="def"
                     /locus_tag="JAM15_14450"
     CDS             complement(18953..19408)
                     /gene="def"
                     /locus_tag="JAM15_14450"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HAT6799453.1"
                     /translation="MAIRKIRTFDDEILRKKSKYVENVDNKIREILNDMAETMYNTPN
                     GGGLAACQVGVLKRLVVIDLGEGLIKLVNPEIIKQEGEQIVVEGCLSFPEVWGKLKRP
                     KKVTVQALNEYGEKIEIKGSGFMAKCLCHEIDHLNGIVFTDKIIEHVKL"
     gene            complement(19380..19643)
                     /locus_tag="JAM15_14455"
     CDS             complement(19380..19643)
                     /locus_tag="JAM15_14455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6799454.1"
                     /translation="MKNKIKILREKLGLTQEQLGRLVGTSRQAINAIETGKNEPSIWL
                     AYDISRIFNEPIESVFLFEESERKSRAQISRGEYYGYKKDKNI"
     gene            complement(19740..20456)
                     /locus_tag="JAM15_14460"
     CDS             complement(19740..20456)
                     /locus_tag="JAM15_14460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6799455.1"
                     /translation="MIKIINAFKQEFEQIKRDAMLFIVCVSPILCGVFIKFGIPLIQN
                     ISLNKFYYQLNLEPYFLMFDLLLAFITPFMFFFASTMVILGEIDDSISRYLIVTPLGK
                     TGYLISRFGIPGTLAFIITMILLIFFSLTKISFLLNLSISLLVLLQGVIISILVISLS
                     SNKLEGMVITKFSGVFMMGILAPFFILNKAQYILFFLPTFWISKAFKEDNYIYMFISI
                     VISLIWILLLFKKFSKKIVK"
BASE COUNT         6701 a         3491 c         1954 g         8354 t
ORIGIN      
        1 acctcaataa atttctataa aaatagtatc attttagtat catcatttat ttaatacatt
       61 atgtattccg tttagattta gttattcgaa aacttagata actaacttgt aatttctaca
      121 gattattaca tactttattg taattatatc ataatgttat aattacatat tatcaaatta
      181 cacactagct tttattcata tagatattat catccttgtg tatatattgt caaagaaaac
      241 atttaattta caacatattt tatatcatat catccaaatt attatataca cagtatctaa
      301 ttaacacatt aacactattg tactttttct aaaaattttt aaataaaaat gacagcttta
      361 atttattatt ttaaaactgc cattaaactg taaatattcc cttttagtat acaaaatttt
      421 acctttatgt taatatattt tacttatata aatttttcat aattaattta tacatataaa
      481 ttagcactat tgctgtttta ttatcttagt tataaataat tgtaattaga taatattcaa
      541 tttctatatt aatatttaac taagattaga taatgtatcg cttatatcct tttctactaa
      601 tggtttcata ttattattat aaatacttat atctgcatta cttaattcca tttttatgag
      661 attaataaga ttttttttat actttgtaat attaggtatg gatttaataa acattcttga
      721 tacagaaggt tttttatctg tgatatgact tagtatacta tctatattta tttcaatttt
      781 attatcaata tcccattgag catttgcaga gattaataac aatccccttg ttcgaatgta
      841 tgagttttca ttatcaatca tttctaggaa tgagtcaaaa aaacaatatg taatatttga
      901 ttttaagctt tcattttcta agaataaaaa agttttatat gcttcattat gattttttga
      961 atataattta ttaataagta aattgagatt ctccaatctt ctcatctccc tcattacaaa
     1021 tatttattta aacaaagtat aacatattca aaaataaata taaataaaaa ctatattaaa
     1081 taaaaatcct aaaattattt gctgtttatt tacaaataat aattctaaaa tatatttgat
     1141 ttatttagta tcgactataa aaataagcta tcaaataatt tatacttgat agcttatttt
     1201 tttataattc tttttttaaa gtttccttta gactatcata tgcgaaatcc attatttctc
     1261 tacaagcaac taaatctttt tttaggtcta tacataactc tgaaccatac tcttttctta
     1321 ctgttgtagt taaatcttta gcatatactt tagctttagt actttcatct tcgtggtttc
     1381 tgccttttac gtatccaatt attatatttg atgcatttac tgcaccacat aaactagcaa
     1441 ccccacaccc tgaacccagt ccacttccta aacaaactgg tatatctgta ttaaattcct
     1501 cattatatgc ttttataact gattctgcac aattaaatcc cttctcatga tattttgatg
     1561 ctataacttt atcacacatt aaaattcccc ctcatttttg taaattaaaa taaattcttc
     1621 attgtttttg taaaaaatac ttctttttac tattattata tcaaatatta acaataaaaa
     1681 catttctttc taagttaact ctgtctttct aaatttaata gtatctcttt caaatcagaa
     1741 tgattcccca tatatccacc aatatctttt ttgccaacta ctctatgaca aggtactatt
     1801 attggaattt tattactttt acttgcttgt cctattgctc ttactgattt tggattgttt
     1861 atatttcttg ctatatctga ataacacaat gtttctccat aaggtatttt taacatttcc
     1921 ctataaactg atttttgaaa ttcagtccct tcaatacgaa tatttaaatt aaagactttt
     1981 ctttttccat taaagtaatc atctatctgg cttattgctt cctttaaatc ttccttactt
     2041 ctctttatat caattccttt tttaatacat tcatttttta aattattaaa tttttcatct
     2101 cctatgtata cactaactat aaaaccatct tcacttaata tgtacaaatt tcctaatttt
     2161 gatttataaa catcatatac taaactcata ttacttcccc cctttaatat cagtatacat
     2221 ataatttttt aactaataaa gagttaccct aaaaaatagg ataactcttt tttatagata
     2281 cttaatatag agtatatttt taaattcatt aacttttaac atatcaaaat ataaatctta
     2341 tatattttta aaagccttag aaagcataag ttttatcctg ttaagttgat ttacctcact
     2401 tgcagaaggg tcataatcaa taggtattat atttgcattt ttatacaacc tctttaattc
     2461 ttttatagaa cccttaccaa ttatgtgatt aggtaaacat ccaaaaggtt gcatacaaat
     2521 aatgttttct acaccttcat ttaataattc aaccatctca cctgttaaaa gccaaccttc
     2581 tccagtttga ttacctaatg acactactgg ttctgtactt ttagcaacat tttttatatt
     2641 ggctggagca taaaatctct cactcttatc aagtgctttt ttatatactc tttgatatat
     2701 tccagttatg tatataaatg cttctcctat cattctactc tttctacttc cttctaaatg
     2761 agtgtgtttg tatatagtat taaaggcaca acttaagaag aaatttgtaa ggtctggcac
     2821 gactgcttca gcaccttctc gctctaatat atctactaaa ttattatttg caattggatg
     2881 gaatttcacc aatatttctc caaccaaacc tacttttggt tttttgacat ctagtatctc
     2941 taaattatca aattctttta ctatatcttt tatatttcta gtaaatacag aaatttttgc
     3001 tttaacaaga gaagttttgc atatatcaac ccatttttca tatagagcat ttgcacttcc
     3061 agtaactttt tcatatggtc ttactctata tagtactttc atcagcaaat caccataaac
     3121 aacagacata aagagtctat tgattaattt tagtgatata ttatccatta taccactatc
     3181 ttctattcca tttacactaa gtgcaatgac aggaacatct ttaaatccag catcatatat
     3241 agcctttctt aagaatccaa tataatttgt agctctacaa cctccaccag tctgagttat
     3301 agtaacagaa gtattattta aatcatattt gccagatttt aatgctgtta ttagctgacc
     3361 tacaactatt atagctggat aacatgcatc attatttaca tatcttaacc cttcttcaat
     3421 tacactacta tcagtatctt ttagaatttc tatattataa ccacttaagt taacagcttt
     3481 ttcaaggaat tggaaatgta ttggagacat ttgtggtgct aatatagtat gtttgttcgt
     3541 tatctgatta tttttagcat actgtatcct gtttaccttt atatttttta catctatatt
     3601 tttgctttct ctctcaaaca tagctgcttt taaggacctc atccttatct tagctgctcc
     3661 taaattgttg ccttcgtcaa tctttataat agtatatatc ttcgattttt cattaagtat
     3721 ttcttgaacc tggtctgtag ttactgcatc taatccacag ccaaatgaat taagttgaac
     3781 aagttccaaa tagtttttat ctcttacaaa actagctgct ttatacaatc ttgaatgata
     3841 tacccattgg tctacaactc taagtggtct ttgtacattg gctaaatgac atatagagtc
     3901 ttcagtaagc actgccatat ctaatgaatt tataagctct ggcattccat gatttatttc
     3961 tgggtctata tgatatggtc ttccacataa cacaatcccc ttcatatttc tttcttttat
     4021 ttctttaagt gctctttcac ctgctgcttg tatctccatt ttaaataaat tctgttcatc
     4081 agtagcttta tcaactgcat gattaacttc ttctttagtt atttttatat cagaaaaatg
     4141 tcttgataat tcatcatata gtcttttctt caatttttcc ttatcattta gacttataaa
     4201 tggatttata taatttatgt tcttatttct tatattctct acattgtttt ttattacttc
     4261 agaatatgat attacaacag gacaattata ataattatct gcatttgaat cctctttatt
     4321 ttcatttgtt acacttggat aaaatatatt ttttatacct tttgcaatta aattttctat
     4381 atgtccatga actaattttc ctggataaca aactgtttca gatgcaatac tagttatacc
     4441 agtttcatat aactgttttg atgacctatc tgaaagtaca actctaaagc ccatagcatt
     4501 gaaaaaagta aaccaaaatg gataatcttc atacatattt aatactcttg gtatccctat
     4561 ttccccattt tttgcttctt ctttttccaa tggtttgtat ctaaaaattc tattgtattt
     4621 gtacttaaat aaatttattg gttttttctt ttctaatcct atttttttat caccataaat
     4681 agcttcaccc ttctcacatc tattacctga aataaaaatt tcattatcag aaaatttatt
     4741 tattgtaaga agacaatgat ttgaacaacc tttacatcta gttacacttg cttctagctt
     4801 gatattattc aactcttcct tagataacaa ggatgttttg tatccacttt catatttttc
     4861 tttagctata agtgctgaac caaaagctcc cataattcct gaaatattag gtctaattac
     4921 attttttcca attagttttt caaagcttct aagcaccaaa tcattataaa aggttccacc
     4981 ttgtacaaca atattattac caatctcatt taaatctcta atctttatta ctttaaataa
     5041 agcatttttt attactgaat aagatagccc tgctgatata tctccaacac ttgcaccttc
     5101 tttttgagct tgttttactc tagaattcat aaatacagta catcttgaac ctaaatctac
     5161 aggattttga gaataaatac cttcatgtgc aaattcttct attgtcatag ataaagaact
     5221 tgcaaatgtc tctaaaaatg agccacaacc tgatgaacaa gcctcattta atattatatt
     5281 atcaattact ccatctttta tttttaggca cttcatatct tgaccaccaa tatcaagtat
     5341 aaaatctaca tctttattga aaaatttagc agctttgtaa tgtgctatag tctctatctc
     5401 tccgttatcg attttaagag cttttttaat aagaccttct ccatatccag ttacagttga
     5461 actcaatatt ttaatatttt ttggtaatat atcatatact tcatttataa ctttaatggt
     5521 tgtttttaat ggatttcctt cattgctatt ataataagaa tatacaagtc ttccatcctc
     5581 atcaataagt gctgctttag ttgtagttga gcctgcatca attcctaaat aacaattgct
     5641 ttttattgaa tttatgtcca cataacttat tttttctttt tcatgtcttc ttgaaaattc
     5701 ttcatactca tttttatctt taaataaagg ttctaataaa tttacttctc catcttcaat
     5761 attctttata ctatccaatt tttctattag agattttagt tgtatattat cttcatctac
     5821 tgataataat cctgctccaa tagcaatata aagttgtgca ttttctggga agattatgtt
     5881 ttcatctttt aaatccaata ctcttttaaa tgcttctcta agttcagata aaaagtacaa
     5941 tggaccaccc aaaaacgcaa catttccttc tatttttctt ccacaagaaa ggacactcac
     6001 agtttgtacg acaactgcat tgaaaatact cattgctata tcagtctgat tggctccatc
     6061 atttataaga ggttgaatat ctgttttagc aaaaacacca catcttgaag ctataggata
     6121 tataacatta taccctttag caagttcatt taatccactg gcatctgtct ttaaaagtga
     6181 tgccatttgg tctatgaatg ctccagtgcc acctgcacat attccattca ttctttggtc
     6241 tattcctcca cttagatatg ttatctttgc atcttcaccc ccaagttcta tgacaacatc
     6301 agtttcagga tgaaaatact ctattgattt tgtactagat ataacttcct gaacaaattt
     6361 tacacctaat ttttttgata ttccaattcc acctgaacca gttattataa tggtagtatt
     6421 tatatctccc aatttttcat atataccatt tagtacttct ttaactgatt tttttacatc
     6481 agaataatgt cttctatatt ctttatgaac tatattatta ctattattaa gtaccacaac
     6541 cttcaccgtt gtagaaccta catcaattcc tatatgaaat aattcatcca ttgtacccct
     6601 ccatatttat atgctttttt aatttttgta agttctatgg ctttatttta agtaagttat
     6661 ttataatctt tatgactaat atttttattt tatgattctt ttattaatca aagcttactc
     6721 tactaggtaa ttcctaattc taaccttaaa ttttaaataa gaacatatag ttagtgtact
     6781 aaattttgtc ataaatttct acagattttt gttacttttt acataaatat aacttaagtc
     6841 taatatccac ttaatgttta tgtattataa attatcttta gtcagaaaaa aatggttgtt
     6901 gatatgtaaa ttcttattac atatcaacaa ccattttttt gtatattatt ttttatctta
     6961 gctgattaca tttatcctac gagtgtaaat ataaagtgag cagctgctcc tgcacataaa
     7021 ccacctattg tatgagaaag aatagcttta cctgccaact gtctagcatt taatgcatcc
     7081 atcataccaa tatgtgtact taaatatcca ctccaacaca tacccatagc tgtaaatact
     7141 gctatatcat taggagttat agctcctgac tttataaact ctggaactag agacattgct
     7201 gcaccaacag ctcccaatga agttataggg aatgctattg cctctggtga tgtaaatcca
     7261 aataatggtt ctaatataaa tccaagttta tctccaataa ctggaagtaa ttttattcct
     7321 tcatatgcag ctcctgtata aacttcttga cctgtaacag ggtctgtaga tggtccaaaa
     7381 gttaataaca tcaccaatgt acatactact aggactccag gaattatagc cattcccata
     7441 tctaccccca ttttaccacc ttcaagaatt gcatctaaag ctctttgaaa tacatttcct
     7501 tctctgattt ctctaaattc atcctttttc tctaatgttc ctgttgcttt atcttcttcc
     7561 ggattgtatt tataaaactt cttagtaaat gtcaacatta ttctaacact tatgacgcta
     7621 cctataattg cacctaaatt accaattaat gctggaagta catattctgt accttgagaa
     7681 atcataaatg ttgttaagat aagtcccata ccaaaggctg ttcctaagtt acataatgct
     7741 ggaacttggt attgtttaaa atactgtgtg aatgttttat ctttagcaaa aggtataata
     7801 gctggattat ctgataaata agttgttata gctcctgcta tactagcacc aggtagtcca
     7861 tataaaggct tcataaatac agcgaaaatt ttattaatta acgctattac tccaaactct
     7921 gaaagtagtg cgcttaatgc gcctgcaaga actgccatag ccataattaa gaaaactgtc
     7981 tccaatagta aagcatgtgc tgtactcatt attactttga acatcattcc tgctcccata
     8041 atactaccaa catacccaaa accaactact agtaatatta ggaaaatgaa ggtttccatg
     8101 cttactgcct taacctgtct cctgtctgtt aacttctcca ttttgaatca tcccttcttt
     8161 tttcgttata aagtttaaca aaaccttttc tcttttttaa ttatacttat aagtattact
     8221 atttgcaact ttatttgtca tttttttatc atttttaaaa tgaaaatcag tattttaata
     8281 ataaaaattt ttcagattta tgcaagtttt cgacatctta tctttcattt tataaaaagt
     8341 atgattcctt actaaatata tatatacttc tctaacgacc taatatacaa atataagttg
     8401 taacttgtat ctttttgcat gaaagaaaaa agattatgaa aaaatttttc cttcaatatt
     8461 tttcataatc ttttttttag ttttatataa ttttttttaa aaattttttt aaaatttgtt
     8521 ttaataaata tatattattt taatttttca gctacatatt ttactaagtc aacagttctt
     8581 gaagaatatc cccattcatt atcataccaa gaaactacct taaccatatt gtcttctata
     8641 accattgtgg atagagcgtc tataatagat gatcttgaat ctcctttata atctatagaa
     8701 acaagtggct tgtcacaata tcctaaaaca ccttttaatt ctccttcagc agcacctttt
     8761 aacacagagt taacttgctc agatgtaacg ttttctttaa gttcacacac taaatcaaca
     8821 agtgaaactg ttggtgttgg tactctaagt gaaaaaccat ttaattttcc ttctaattgt
     8881 ggtaatactc ttgacacagc ttttgctgct cctgtagtgg taggtattat agattcagcc
     8941 gctgctcttg ctcttctcaa atctttatgg cttttatcta atattctttg atcgttagta
     9001 tatgaatgta ctgtagtcat taaccctttt actataccaa atttttcgtc caatacttta
     9061 gcaaaaggag ctagacaatt tgtagtacaa gatgcatttg aaattatatt gtgcttttca
     9121 ttatcatatt ctttctcatt aactccgata actatagtta tatcttcatt ttttcctgga
     9181 gctgttataa ttactttttt tgctcctgct ttaatatgct ttgctgcctt ttctctttgt
     9241 gtaaataatc ctgttgattc tattactata tcaaccccca gttctttcca tggtaattct
     9301 tctgggtcat tatatcttaa tatttttatc tctttagagt ttactactag agtatcttca
     9361 tcctttgcct ctacttcacc tctaaaagtt ccatagcatg aatcatatgt aaataaatgt
     9421 gccaaagatt ctgttgttgc tcttgcattt atggctacaa tttctatatt atctcctaat
     9481 tcttcttgag ctattcttaa tacagctctt cctattcttc caaatccgtt cattcctacc
     9541 ttaattttca ttatgaaatg tctccctcca ttactatgtt tttacatgat tattgtacac
     9601 taaataaatc atttgttcaa tactttttct tgattaaata atcaaattcc atgttttttt
     9661 attatcaaaa gacaattagt atatcatttt ctttatttca cccctcattt agtatgtact
     9721 ttttagtgta aataagctga aatcatttat tttactcaat gtcccttggg acatattttg
     9781 ccatcttttt tttgaatttt taaactatac ttatttttaa aaataatata tcttcaagaa
     9841 tctcctctaa tttaaaataa taaaaacaaa tttttattta gttcaaaaaa tatatgattt
     9901 tttaaaattt gccacaatta ttatttatat atcaaaatat aaataataat tagcttattg
     9961 ttaactaaat tatggaaata tacttaattg aaaacttaaa tttatttcct tgtgttatca
    10021 agatttcatg cttaccattt ccaatatcat gctcaccaac ttttgatgtg cataaactat
    10081 ttcaagtaaa aatgcacaac ctatcctttt tgatatgaaa aagcagtcaa tcataaatat
    10141 caactgcttt tatgtactga atatcaagtt atagacaagc tggaatttat tttgagggtt
    10201 tttctttctc cttaactaaa ttgctttcaa aagtaacctt tacaactgca tgatttattt
    10261 taattccggt aaagcatata gcatactctt tctctttttg tatattagaa agagaaattg
    10321 tgaatgtatc attatcaacg cttccatgcc atgtattact ccataaagtt tcatctgttt
    10381 tattgtcctt tatttccaca ataccactat ctccatccat tttaaaagaa atctctgtgt
    10441 ctaaaacatc tatatcatta gacacacaaa acaaacgtgc attaacaaat gggtctgaag
    10501 tatcataatt tttatctaag tccatttcaa tggttgtttg tcctgattct ttgttgttta
    10561 aattattata tttactttca ttgctttttt tacaagctgt caagctaacc acactaatga
    10621 tactaattaa aataataact aattttttca tagaatttat ctcctttaca atttctaatt
    10681 tttaacccta caaactataa tattaaacta atctactatt ttacatcaaa tttttcaatc
    10741 attcagcctt taccttttct cattttaatt gcaaatatgt taaataattt tggaatttta
    10801 attattgtag tatcttaaat tggtttataa catattatga aaatttaaga gtcaagtaac
    10861 ttatttaaaa atacacaaaa ttatacttta ttgtataaaa aaagagatta taatttatac
    10921 aagtaaaata aactttatta ttttactctt ctatataacc tcttttctat atatctattc
    10981 aaataattta gcccctaaac tcacaaacat ttgtaaaatc aaaaatgctt ttgtgtccat
    11041 cttatgatta ctttgtaaaa tctcttttgc atcttcttgc gaaattaaaa gcgcttcaat
    11101 ctcttcatct ggttctaaaa attcatctgt tatatcacca tcacatatac aataaacaaa
    11161 ggcaacagat tcatcactca ttccaggaga taaataaact ttatcaatac ttttattttt
    11221 tttaatttct aaaagagtaa gtcctgtttc ttctctaagt tctctttcaa cagaaatatc
    11281 tatagactct ccttcatcaa caagacctgc tggtaactcg tatatatatc cattaatagg
    11341 tactctaaat tgtcttatta aaattaattt tttactactt ttatgaagcc caactattac
    11401 aactgcatct acactatctt cttcattctt caaataaata ttttttaatt gctcactact
    11461 ttttcttgat gctaccatcc aaaccttatc ttcatctaat ttgtttttat actctatttc
    11521 aaaaagtcct ataaacttat tttcaatcat tggatttaca ttctttatta tagttttttt
    11581 caaatttact acgacctttc ttttttaata cctttttaac atcattaagt aaatataata
    11641 tcttaacaag tattcaacaa cttattatat ttccatttca ggattatctt tatctacaaa
    11701 acctactttg atttcacaat taaatatttc ctttaacaat tttgctaatt cttctcttgc
    11761 actcattacc ttatctaaat tagcatcagt aaaaccatct ataggaaaaa atatattttt
    11821 tgagctatta gtaatttttc cttcctctcc ttgtctccat atccatcttc tagtttttac
    11881 catgtctcca actgaataaa ttaattctcc ttcttccatt aattcaacat cagtttctcc
    11941 aaatggtaca aatttatccc cttttttaga aaatctaaca tatacatcat catttctaaa
    12001 atccatatca tgagcaccca ttggaagtaa atattttaaa gaaatagagt ttcctaaatc
    12061 tacaatagga tttatatgag gaagtttctt attcttagca acccttgttg tcattgcttc
    12121 tatcgaactc ataaatttat ttgggttcat gcctagactt ctaaatgcct ctctatatgg
    12181 tataatttct tctgattcct ttactttttt atctttgaag taatcttcta ctctatctat
    12241 acttatatct aaaaggttgc ttattctttc tatttcttta gtattatcta ttccttttgc
    12301 aactactaca ccaaagcata cattttctaa tttatcaaaa acttcttttt ctactataaa
    12361 tttcattttg ctttatcctc ctgttatttt acattatttt ctaaatagat tttatcactt
    12421 tgtgtcttat aaatataccc cctatttgct aattgtttaa tttttttaaa ttttccaatt
    12481 aatattatat ttgttcttat caaatatttt atatgtacta attacaaatt taactttcca
    12541 aaacaaatat cttgttttat aatgtataat atatttttat ggaggcaaga ctgtgaaaaa
    12601 ttttattcta atatatttta tagtgattaa ttctattgct ttcttttcaa tgtacataga
    12661 taagaaaaga gcaattagaa acgaatggag aataaaagaa gctactctta tgtctatagc
    12721 agtaattgga ggtagtatag gttctatgat tggaatgtat tcttttagac ataaaactaa
    12781 acacattaaa tttacatttg gtataccatt tatactattt ttacaatttt tattagtata
    12841 tttttatatt ttaaagtaat tgaaatataa aaccttattc ttttcaataa attaaggtgt
    12901 ataaaattaa aaactttata cacctttttc tagcaattat taaaaagata tttaattaaa
    12961 attaatgacc cttatgttta gcttttctct tttcttgttt caaattaaat agtctttctt
    13021 tttcttcttc ttttctattt ttagctaggt tttttctatc ctgttttctt tcttcatatt
    13081 gaagattaag agcattttga gccttagtcc ctatagtttc tttttcttgt tcctttttta
    13141 cttttctctg cattcttttg tatccaattt tgtctttagt cacatttttt tctaatttaa
    13201 tgctaccaaa atctaatgag aaaaatcttt caagtataaa ttcatacact tctacttctt
    13261 taggttctgc tccaaaaact accctacatg cttcatattt tttaccatct tgtctttcaa
    13321 atatacctac ccaaaatggt tcttcaaata agactgttaa ttttccacta attttgtcca
    13381 ttgctagttc ctccttaaat tactttctaa agaacggaca accaaggagg caggttactg
    13441 acagctattg ctgcgtctgg actaccaacc agactgtgtt tttatcttta tagattaaat
    13501 attatctttt ttaatcatgc ttgtcaatct tagtatcaac atctatcata ttgatttaag
    13561 tgaaatcaag ctttttaact ctactttatt attgttaaca ctaagaaaat taattatttt
    13621 tcataataaa ttagttatta tacttattta aatatcaatc tttattgttc cctgcataaa
    13681 caagactgct tcaccagaaa tttttacagt attatccttc aacacttcac actgaattat
    13741 accaccacga ttagaaagtt gagcagctac cattttgtgt tttcccaact tttcagacca
    13801 gtatggaata agattacaat gtaatgaacc agtaacaggg tcttctgaat ctaattctgg
    13861 acaaaaatat cttgatacaa aatctgtatt acttccttgt gctgtgatta ttatacctaa
    13921 ccagtctgtc aatttacgca attgtgcgta attaggttta taatttataa cttcttgttc
    13981 actgtttagc aataagatta aatctcttga agaataaaca gcacttggta cacagcctat
    14041 caaattagct tgttatggtg ataactctat ttcaataggc attatttctg gaaatatcat
    14101 ttcatataga tttccatttc gtgtaacttc aagctttcca ctttgagtaa agaaatctat
    14161 cttttttaca ttaacatcaa taaaatttga tattacataa gctgctgcta aagttgcatg
    14221 accacataaa tcaatttctg ctttaggagt aaaccatcgt aattcataat ttcctttacc
    14281 tttaactaca aatgctgttt ctggtaaatt gttttcttct gctattttct gcattaactc
    14341 taaaggtatt cttctgtcaa gaacacaaac tccagcagga tttcctttaa atagtttagt
    14401 tgcaaatgaa tcaactatgt agtattccat tatttgacct ctctttccaa cataaaatat
    14461 acattaattt acattcaata aaactttaaa tttcttacat atatttttta atattgctct
    14521 gctcaacaac ttttttacct aacaatgtaa ttgctttttt tgcacaatta tttacacaac
    14581 gataacacat tgtacattgc ccatttgcaa caatcataca atttttaatt actagattct
    14641 tcattggaca taaattaaca catttaccac atacaataca ttcctcagta ttaattttta
    14701 gtttatctgt atacatattt gttttattga taaaatacaa tcgttgtcca aataacccta
    14761 caatatgact caaaaaacct aacccttctt ttggtggtga cccatgtttc agttttttag
    14821 cagctttagt tactttcttt tctgctttta ttacaagctt tttattatac tctaaagaat
    14881 gttttaatac cttttcatct cctatactat ctggcatctt cacatgtaat ccaccaacag
    14941 ttatagcacc gtattttttt aatattctag ataacacacc agagccatct ccactaaata
    15001 gagccatagt tgcaataata aaaacacgtt taccattcca caaagttgaa tgatttatta
    15061 taaaatcttt caatattttt ggcacattac tatattgcac aggataacta aaaataatat
    15121 tctcatgatt attgatgtgc tgtaaaagtt cattatcttc aatagaataa gaatttgctg
    15181 ttatatcata ttcttgtaaa aatttttcta cacagtatct tgaatttcct gttccactaa
    15241 aatatattcc tatcatagta cttctcctaa tagctaagat tatatagctc tattcttaaa
    15301 attctgactt tttatattat ctaaattaag tagtttattt aaataatata aacttaattc
    15361 aacaagttac ctactgaacc tcccatgact aaagtcatag ggttcctgct tgatagaatt
    15421 ttgcataatc aatttactaa atacttgtct aattcttttt ttatcatttt aaatatacat
    15481 tttaataata ttagtaagct atacttcctt aaacatatat tttccctaaa gtaaaactat
    15541 tgatgattat tccattatat aacttaatta taaatttagt aagttcatca catactatac
    15601 ccttaattct caattataaa gttccctaaa aaatatttga aaatttaact atgaaaaaat
    15661 ttcctattgc ctaatatgta taagtaagga gtactatata gtactcctta tattgtactc
    15721 ttataacatt gatgtcttaa tattatttta atcttaatca ttattgattt gatttaaaat
    15781 tataaatagg ttccaatatt ttaattatgt caactatatc tcttgtagtt ttaataatct
    15841 catcaattgg tttatgtgct tgttgcactt tatcaatagt attaattaaa tccatttaca
    15901 catctagcac ctgtatggca atttagcatt atttttatct tatactttgt tgtaaattct
    15961 tgattacata attctattat ctaacttata gctgtgcaat ctacattatc tgtaaatatc
    16021 tttgctttat atattttccc tgaacctcta acattaatat aacagccttt ttgctataca
    16081 cttttaacta tatacttaat tttaataaca ttacttgttt ataaaaatat actatagata
    16141 aatttcacat aaaaataata attcaagtat tgatttttat ataagcaaat ttgtaatgta
    16201 ctaaaaataa cataaaagtt tccatctttc aatatgtaag cttttattat gttattttat
    16261 tgttaaaggt ttcaagtttt tatttattca ttttaaaaaa attattattt ttgtaaaact
    16321 aatcccatag tcatactatc gtcagaatat gcttcaccct taacattact aaaaaactca
    16381 atggacttaa atccaatatt ttcaacttct aataagaaac tttcttttga aaaatagtga
    16441 ttccaaacat aaaatacatt ttcatctttt tcggttatta caagagtttg ttctaatgta
    16501 ttataatcat tgtatttaca attatcttgt agacacatat atttttcatt actccaaaat
    16561 cctccatctt catttatttc ccaatattta atttcctcaa aattattgta tttatttatt
    16621 gtaaatacat ctaatattaa ttttcctcca ggttttaaac tatcataaat tttttccatt
    16681 aataaccttc tattttcagt tgacaaagct ccataatcac aataaattaa agtagacaaa
    16741 tcaaattcct cattatagtt catatttaaa taactttgaa acaagtaatt tatgtttaaa
    16801 ttagtctcct tatttctatt ttgtgcatag ttaatagaac gttttgagaa atcaattcca
    16861 gttaccttat aacctttttg tgcaaatttc tctgcatata aacctggacc acaacctaaa
    16921 tcaagtaatt taggataatt aactggattt gcaactgtaa ctatccaatt tacagaatcc
    16981 tcgataaagt taaaatttct acttgctcct tcaaaattag tgtctaagtg tgcttttaat
    17041 aattgctttg aaatatactc atcatcccaa aaattaattt cactttgttt ataaagctct
    17101 ggtctttcta aatacataca taatttgttt aacaaaacat accactcctt aaaatttatt
    17161 tttaaaataa aaaaaccaca gagtttactc tgtggtttaa cttcaaaaag atgagtttaa
    17221 ataagagtaa aatagaacca aatattttta agcacaacaa taaaactata gctttacttt
    17281 gtttgcttat taaatttgat tttattcact cttttccagc aatacttata tcaacgattt
    17341 tatgatatca aatatcaccg aacaacatca tcctttcata tttttatttt atgaatcaat
    17401 tatatattta aattttatat ttgtcaataa attttaattt taataaattt taatcatcat
    17461 agtaaaaaaa atttttttta tataaaacta atcaaaaaaa gatatctgta catctcctga
    17521 gttttttaac ttttccttca ttattttaga gtaactgctt gatagagaat atttatatct
    17581 aagttcatta accattttat acaattgatt tttatactcc ctattaagtg aacctgcact
    17641 atatagtatt gataatttat caaataattc aggaagctct tttttaacaa agtcaaaaaa
    17701 aacacctcta gttatacccc ttaagtataa agtcccaggt aaaacataat gtacattaca
    17761 ttcttttgca tgtctaaata gcgaatttat attatcaaaa tcatctgtaa tatatggtat
    17821 aattggcata atatgtagac caactgatgc gttagttttt ctaaattctt ttaacatttt
    17881 aaatcgtctc attgaatcca caccatttgg ctcaataagc ctttgtgtat cttcatttac
    17941 tgtggtaatt gtagatgcta cattgatata tgtaatccta gatagcttat caattaaatc
    18001 gtaatctctt aaaattaaat ctgactttgt agaaataata gctggtgtct tgtattttat
    18061 cagcaggttt aatatttctg gcataatttt atagtcagct tctattggtt gataactatc
    18121 tgtaactcct cctatattga ttacttcttt cttccattta ctgcttttaa gttgtctctc
    18181 aagtttttct actatatttg tttttacata aatctcttca aaataattat tggagttaat
    18241 gtacttatga gagtaaatag cataacaata tttacatcca tgctcacatc cacgataaat
    18301 atttaaatcc catttatatg gcatactcct ttttaattta ttacaagcta tttcacaatt
    18361 tattggaata tattttattt tattatacaa ataatcacct ctttatatac aataatacta
    18421 taatgttaat ctatagtaat taaaacatga tatttccaga ccacaattca taatctttgc
    18481 tatatttaca aagtaatata ttccattcat ttattggtat tcctccacat gttgcttttt
    18541 cttctaaatt atataagcat tgctttaaat acattttatt atgccaatca tcatataaat
    18601 tttctaaatt taaactatgt tcattagata tatcatttgc aaaatttcta tttttccatt
    18661 ttaatatact tgtatattta agttcattag gtttataatt tctttttaac atttcatcat
    18721 gtacaatttt tgtataaaat ttaaattcat ctatactata attcaatact ttattcacta
    18781 atagatggtt tggagtacct tttttatcta tagaaccttt tatagcaagt agctctctcc
    18841 attgacttac taattgattt ttaggtaata catcaattaa atccttatgc cataatctca
    18901 taatttaact ccttactata aaatatttta taaattcaat aaccaatcta tcttacaatt
    18961 ttacatgttc aataatttta tctgtaaaaa ctataccatt taaatggtct atctcatgac
    19021 aaagacattt tgccataaaa cctgaacctt taatttctat tttctcaccg tattcgttta
    19081 gagcttgcac tgtaactttt tttggtcttt ttaatttacc ccatacttct ggaaaactta
    19141 aacatccttc aacaacaatt tgttcccctt cttgtttaat aatttcagga ttaacaagct
    19201 taataagtcc ttctcctaaa tctataacaa ctaatcgctt taatactcct acttggcatg
    19261 cagctaatcc tcctccattt ggagtattgt acatggtctc tgccatgtca tttaatattt
    19321 ctcttatctt attatctacg ttttctacat acttactctt ttttcttaaa atttcatcat
    19381 caaatgttct tatctttctt atagccataa tattctcccc tacttatctg tgctcttgat
    19441 tttctttcac tttcttcaaa taaaaataca ctttcaattg gttcattaaa aattcttgaa
    19501 atatcatatg ccaaccatat tgaaggttca tttttaccag tttctatagc atttatagcc
    19561 tgtctagatg ttccaactaa tcttcctagt tgttcttgtg tcaatcctaa tttttctctt
    19621 aatatcttta ttttattttt catatttgct ccattcatgt aaggttaact ttacatctta
    19681 aatgtaacat ttttcaacat tactgtcaag tcaaccttac atttatatat taaattttct
    19741 tatttaacta tttttttact aaacttttta aataataata aaatccatat taatgatata
    19801 acaattgaaa taaacatata gatataatta tcttccttaa atgccttcga tatccaaaaa
    19861 gttggtaaga agaacagaat atattgtgct ttatttaaaa taaaaaatgg tgctaaaata
    19921 cccatcataa aaacacctga gaatttcgta attaccattc cttctagttt atttgatgat
    19981 aaagaaatca ctaatattga tataataact ccttgtaata aaactaataa agaaattgat
    20041 aagtttaaca agaaagaaat tttagttaga gaaaaaaaga taagtagaat catagtaata
    20101 ataaatgcta aggtacctgg tattccaaat cgtgaaataa gataaccagt tttaccaagc
    20161 ggagttacta ttaaatatct tgaaatgctg tcatcaattt ctcccaatat gaccattgta
    20221 gaagcaaaaa agaacataaa aggtgtaata aaagctaaaa gtaaatcaaa catcaagaaa
    20281 tacggctcta aatttaattg ataataaaac ttgttaagtg atatattctg tattaatggt
    20341 attccaaatt ttataaatac tccacataat attggagaaa cacatactat aaaaagcata
    20401 gcatctctct taatttgttc aaactcttgt ttaaacgcat ttataatctt tatcatagtt
    20461 ttactccacc tacctttttc caactgctac aaataaaata
//
LOCUS       DACTZW010000077        20342 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.077, whole genome shotgun sequence.
ACCESSION   DACTZW010000077 DACTZW010000000
VERSION     DACTZW010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20342
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.077"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(101..727)
                     /locus_tag="JAM15_14465"
     CDS             complement(101..727)
                     /locus_tag="JAM15_14465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799456.1"
                     /translation="MKINIKSKLSEFIKQNNLFDDNRIISYLPNITIETDKIKTIMIN
                     EVVPTNTNDDFYSVDKDADYLKTTIPLFDSAGIEVSNINDILDMGIYITNAVKLPKSE
                     YTITRDTIKLHMPILEEEIKLFKNLEVVMLMGDVAKKSFNMITKKHIKKNVIPSISTY
                     KLRNNELYYDNLRVFPSYIMTGGNILIEKSKFEMASEDIKKMFEIING"
     gene            complement(870..1127)
                     /locus_tag="JAM15_14470"
     CDS             complement(870..1127)
                     /locus_tag="JAM15_14470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799457.1"
                     /translation="MILNRTELFRGYSLNRFNEICNILSVNKIKYKYKVKNNAYSKKP
                     FFNEITLGNLGQKEDFSYEYLIYVHKDDYEQAESLINSKLR"
     gene            1453..1965
                     /locus_tag="JAM15_14475"
     CDS             1453..1965
                     /locus_tag="JAM15_14475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799458.1"
                     /translation="MKKISQEKISTHIQEVPQEKIEQWKSLYEKYKSILKVNSKSVLE
                     IIEFLKQKYVIVEETSEEFKHVVINNIKLNKPFSQKISSDKELKPIVFTIPNEGNAKK
                     LYDTQEETYSGCKIIVGMEFETGCVFVEGSDELNDEITSFKGLDKYDISNYYLVANYI
                     RCLKKYKLID"
     gene            2220..2924
                     /locus_tag="JAM15_14480"
     CDS             2220..2924
                     /locus_tag="JAM15_14480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006525683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HAT6799459.1"
                     /translation="MKDLILETKNLSKRYGEQMAVNNVSLQIERNSIYGLLGPNGAGK
                     STTLKMLVGLLRPTDGRIIFDRKPWKRESLAKIGSLIESPALYGNLTAEENLLVHTKI
                     LGIPKDKIYEVLEIVNLKNTGKKRASQFSMGMKQRLGIAIALLSDPELLILDEPTNGL
                     DPFGIQELRELIASFPKKGITVILSSHILSEVAQVVDNIGIINGGRLLFQGMPDPNEN
                     LEEFFTDVILKGGQNR"
     gene            2921..3691
                     /locus_tag="JAM15_14485"
     CDS             2921..3691
                     /locus_tag="JAM15_14485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HAT6799460.1"
                     /translation="MNALQSELLKYKRTFMGKLIVFFPVSFAAYAFIMQSTLMQNPLS
                     QTTSWAWQSLLALIFNWWSFLFLPIGFALFATLVAFQEKKAGNYRALRTHNVSPMTLW
                     INKVIAMAVYSFISTLVLIFVTIITGLILKAGPVPFGQIIGASIVCWVVSLAILPLQL
                     WLATWKGMFLSMGVGALGMIFGVLAATKPFWIAVPWSWAVRMVCPIINIHPNGTVLEA
                     GDPLLNTSVIPIGIVVSLVVFIVLTALTAAWFNRRDDK"
     gene            3688..4464
                     /locus_tag="JAM15_14490"
     CDS             3688..4464
                     /locus_tag="JAM15_14490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HAT6799461.1"
                     /translation="MIKLLSSEWLRAKRTAVQGLTLCMPIIFSLCVVAYLTIKSGSTQ
                     EFAFEGFFTVWTVFIIPIGVGILAGFIVQEEELAGNFNGFLCVGISRVRLYLGKFLFL
                     LFCLTICTFIATLILCIGMSIAVPSGATIWLFLSAAGLVVIGTLPLLAIHLWVSFAWG
                     MGASIGISIGGILMAAILGLTSVGEKVWAFVPWTWPVKLGMLPGIYFIKEAETISTEA
                     FYSKVMQTASIELIVVAIGLIIFLIGGVIWFKMWEGRKSY"
     gene            4519..5211
                     /locus_tag="JAM15_14495"
     CDS             4519..5211
                     /locus_tag="JAM15_14495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008754589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6799462.1"
                     /translation="MSKILIIDDEMDLVMLLEDELKAKGHEVLIAYDGQAGIELSKQE
                     PDLIILDIMMPKMNGFEVCQAIRDDVLCPIIFLSAKQSETDKIKGLTFGGDDYVTKPF
                     GLRELMARIEANLRREKRSQYINEENKRSTLYFGKLCLYMKERAIKIDGKNIDLTKIE
                     YDIVELLALHAGQVFSREQIYEKVWGCDSEGDSSTVVERVKKIRAKFSAVTPEKEYIS
                     TVWGIGYKWNKM"
     gene            5230..6654
                     /locus_tag="JAM15_14500"
     CDS             5230..6654
                     /locus_tag="JAM15_14500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAT6799463.1"
                     /translation="MKNQSLIAQFRHTFIFIIIASIVATVITYVFAIYLYIYSLNKDI
                     YPPNYYERQVPRIEKYINEKNIALLSQSNEEGLKRTIRGDDMLYQVVDNNGNILYGTN
                     PKKLFKTKEELFNNFINKTVRKGGYIHTVPIKGDNGKIEGAVILFYQVKITFANSRGR
                     FVFAVIIMALFSPFLYIVGFTRWLSKRFVKNINQPLHLLIDASKKIKEKDLDFEIDYY
                     SDNELGKLCSAFSEMKDELKGSLSAQWKMEQERVEMVEALAHDLKSPLSIILGYTDAL
                     IGNNTDDNEKLHRYLTVIRENTEKSVALVQKMQYTSDLEKSNIQLNLVPINLPEFLRQ
                     KVQDYELQAHQKEVELILKMQGNIQSPIQIDVDRLTRIFDNIISNSLQYTPSGGNISI
                     TVKDEKNCISYEICDSGRGFSSKDLKKALDKFYRGDEARQTKGGHSGLGLYIVKQLVE
                     QLGGSVKIENSKSGGACVKFWHSI"
     gene            complement(6894..9362)
                     /locus_tag="JAM15_14505"
     CDS             complement(6894..9362)
                     /locus_tag="JAM15_14505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6799464.1"
                     /translation="MKNYLSLSIKELKSQKLMTTFIIIAIVLSTIMTTVVGQSIGILQ
                     NLRIEQARSFNGDRHVSFHQLTKNQVDDIKKDDRVYQAGTSITIGSSKIKDSGISVLV
                     KEYDKTGLSNYPKLMKLKSGHLPKDKNEIALDENTLKLMGIKPRLGVTIPMNLDISLL
                     NDTIPPYNYTANFKLSGILEDDYTGYVSGIVNGIVGKGTSENLLPKRYILSSLDFKIK
                     QQEKFQEIVNQLAKKINLSHNSIQYNWIYLNALKIQFEKDENSSNSDGISMIILVSLF
                     VALLVLLASGLVIYNILKISVTKKIKEYGCLRAIGAEPNQIYKIVILQILILCTVAIP
                     IGAVIGIISSKGITGMVTNILNPDILLANDNKEITELIHKNTTAYMFPLVLSTNVSLI
                     FSFISALPSAIYASRVSPKIAMAGSTTKIKRKIKREKAIKNFERHLAWLNLKRNKGRT
                     IITILSLFMSITVFVALSEFSNVLDVSRSVSNLKEGDFSLTNEISGFDKSTLDKIDKM
                     KNVNRTSFIKYSEYKQGEIDTDINFENSGEMLKIIGIDEQTLKDLMPSITDSILEDFK
                     NGSICFIKNPIAISTPGVKTRHTNLKPKDSITINKKQLDIYSTVDKMFFLQGNGWING
                     VDVIVYDSVYNTLTNKNKFNQINIYAKDKSKLEQIRLSIEQICENNPGSHWISYIESD
                     KQLKESFKQIEFLAWAVILFVGLIGTLNIINTTHTNINTRTNEIGVKRAIGMSNISLY
                     KMFLWEGVYYGIFAAIFGSIAGYASAIIINMATIEKLDFTNIPITSILQATIISVLAC
                     IIATLIPLRKVKKMNIIDCIDINL"
     gene            complement(9365..10033)
                     /locus_tag="JAM15_14510"
     CDS             complement(9365..10033)
                     /locus_tag="JAM15_14510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6799465.1"
                     /translation="MIIKAKQLSKIYGSNNNKVIALNNVNLEINSGEFVSIIGPSGSG
                     KSTLLHILSGLDNPTSGQVLLDDKDIYKHTEKELSSLRRKSFGFVFQQFNLLPVLTAS
                     ENISMPVLLDKKQPDKDYLNEISSLLRIADRLNHLPHELSGGQQQRVAIARALIAKPD
                     IIFADEPTGNLDSKSGSEVMNLLIKTSKQFGKTLVVITHDDRIAKLADRKISIIDGVL
                     MEVK"
     gene            complement(10319..10846)
                     /locus_tag="JAM15_14515"
     CDS             complement(10319..10846)
                     /locus_tag="JAM15_14515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014118918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HAT6799466.1"
                     /translation="MKSFANNITFSRIVFALLMLSSTFCSLPFWICYFWCGISDILDG
                     LIARKLRQQSGIGAKLDSIADFIFAVTILVTVGKNIALPMYLWWCIVAIALLRLISYS
                     IGFFKYHTFSSLHTLMNKITGISIFAFPLLYICFGLDVAGIMICIVAFLSSFEEIAIM
                     IKSKELNRDIKSIFM"
     gene            complement(11063..12223)
                     /locus_tag="JAM15_14520"
     CDS             complement(11063..12223)
                     /locus_tag="JAM15_14520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAT6799467.1"
                     /translation="MDKINNMSLKKAFFVLTLSSLIIASVLTTFAYILLNNLYNSIQD
                     KYLKTPINTGIITIVQNNVNQFSDYDKTLLNIINILQLVLPLIFFIGLLLLADIIFYK
                     VKLKTPIEILNKGAMEISNNNLDFCLEYNNNDELGNLCNAFEKMRSELNKNNINMWTM
                     INDRKQLNAAFSHDLRNPLTVLKGYSNYLTKYIPTGKLSDEKILSTTQLMSEHINRIE
                     YYVENMSNAQRLEDLVVSKSMSNINKFIENLDENISIIAKQEGKSFTLKSQINNINLF
                     FDENIILRVVENIISNAFRYARNNVSILIYLEQELLTFVIEDDGIGFSKESLKLALRP
                     FYRDKTLNDSNPHFGMGLYISKILCEKHGGSISIENNSTNSAKITAKFSTRN"
     gene            complement(12211..12885)
                     /locus_tag="JAM15_14525"
     CDS             complement(12211..12885)
                     /locus_tag="JAM15_14525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6799468.1"
                     /translation="MNNKILVVDDEEGIITLLKDYFEMNGYEVYTAQSGKDSLKKISK
                     NPDIILLDINMPEIDGIEVCNRIRDYVSCPILFLTARIENTDKINGFRAGADDYIVKP
                     FDLDELGARVSAHLRREQRKSNQTKIKFYNDLTIDYEKRLICIYNNQISLSKKEFDIV
                     ELLSMNPGQVFDKEKIYDRVWGYNSNGNSDVIMEHIRKIRIKLSKHTLENYIETVWGV
                     GYKWIK"
     gene            complement(13699..14526)
                     /locus_tag="JAM15_14530"
     CDS             complement(13699..14526)
                     /locus_tag="JAM15_14530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HAT6799469.1"
                     /translation="MNFYKIAVCQMMTTENKIENINHAVDMVTEAAINGAKIVVLPEM
                     FNCPYENKYFPKFAEEYPGETTTILSKLAEKHGIYLVSGSIPELEYGKIYNTCYVFDK
                     NGALIGKHRKMHLFDIEVTGKVSFKESDTLTAGNDVTVIDTEYGKVGIAICYDIRFPE
                     LSRLMALKGVEIVILPAAFNMTTGPAHWELSIRMRALDNQIFYVGAAPARNMNASYIA
                     FGNSRISDPWGRIIAQADEKECIIYADIDRDLIPDIRQQLPLLKHRRTDLYELNTLK"
     gene            14908..15228
                     /gene="sugE"
                     /locus_tag="JAM15_14535"
     CDS             14908..15228
                     /gene="sugE"
                     /locus_tag="JAM15_14535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010073336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HAT6799470.1"
                     /translation="MKWLFLFVAGLFEVFWAFQLKNSHGFSKLTPSILTVVGMIVSFY
                     FLSLALKHLPLGTSYAIWTGIGTVGTAIVGMAILNEPISISRIACIGFIVVGIVGLKL
                     LSTN"
     gene            complement(15361..16041)
                     /locus_tag="JAM15_14540"
     CDS             complement(15361..16041)
                     /locus_tag="JAM15_14540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004614648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HAT6799471.1"
                     /translation="MKKVYQGKTKDVFELDNGNYLLKFKDDVTGKDGVFDPGENSVGL
                     SIDGIGRANLETSVKFFEILNNAGIKTHYVSANLEEATMEVLPAKVFGNGLEVICRYR
                     AVGSFLRRYGSCVEEGAKLDCYVEATLKDDDRCDPLITSEGLEALNIMTQAQFDSMKS
                     MTQKISNIVRDTIAEKGLELYDIKFEFGFYNDEVILIDEIASGNMRVYKDGVIVDPMD
                     LTALLLDK"
     gene            16437..17489
                     /locus_tag="JAM15_14545"
     CDS             16437..17489
                     /locus_tag="JAM15_14545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HAT6799472.1"
                     /translation="MKSVRFYGIRDTRVEDVDVPKILEKDDVIIKVKVAGICGSDISK
                     YSKTGPHMVGEILGHEFSGEVAQVGKEVRSFKIGDRVAVCPAMPCFECDECKKGLYSR
                     CNNVAIIGNKELGGCFAEYTKVKERNLIKIPDEISYETAAALEPVCIAGHGLFRSEAK
                     VGDTVVVLGTGTIGLFSIQWAKIFGSTKIIAVDVFDEKLDLAKELGADICINAKEKNI
                     VEEIKRLTDGDGADIVIESAGTPMTCGQVLLLAKKGGTVLYAGVPYGDVALTREQFEK
                     IVRSELTVKGTWFGNSFPFPGKEWSAGLYHMQKGDMNVEKLVTHRINLEEVPAYFEKV
                     YKRDIFFGKIMINIDN"
     gene            17536..17952
                     /locus_tag="JAM15_14550"
     CDS             17536..17952
                     /locus_tag="JAM15_14550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAT6799473.1"
                     /translation="MIHMTGIIIATHGNMAKAMLESAELIVGKQENVETLGLNHGDSI
                     DEFSRRLEDRIEKYKDEGVLVLLDFYGGTPFNTSAIIINKFAKVCELECLTGVNLPML
                     LELFLNRDTMKLKDLKNLCEEVGISGIKDVKTVLKL"
     gene            17981..18454
                     /locus_tag="JAM15_14555"
     CDS             17981..18454
                     /locus_tag="JAM15_14555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAT6799474.1"
                     /translation="MSNIALTRIDDRLIHGQVITAWCKITSAKRIVIVDDLVVKDPFI
                     VQVLQMAAPSTVKVEVHDVESGAEVLKSHNGDEHLIVLVKYPKTVLGLVNSGVDLKEL
                     NVGGMGAGLGRKSFYKNISVSDEEKEIFRELISKDVKCFIQIVPDAKKIDVGTLL"
     gene            18501..19259
                     /locus_tag="JAM15_14560"
     CDS             18501..19259
                     /locus_tag="JAM15_14560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAT6799475.1"
                     /translation="MHISLIQAVLIAIFYYLSWSPWLTYVGFFTWNRPLLAGFVTGII
                     LGDPVQGAIIGAGINMIYLGFISAGGAQMGDPAFAGYVGTALAIASKLDVSTAMAIAV
                     PLGTVATVLWIGKMTVNSFFAHWADREVQKGNVDRVAFINIVPPQILLFAMSFIPALL
                     VVYFGPNAIDGMLEVMNENVLHVFNVIGAMLPALGIAMNLKLIGNKFTMPFFILGILM
                     AVYFKVDIIVISVIGVILALTITSIKYGKDSATS"
     gene            19283..20122
                     /locus_tag="JAM15_14565"
     CDS             19283..20122
                     /locus_tag="JAM15_14565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAT6799476.1"
                     /translation="MSDIKNEVSKKTLSKKDVIKSWLRWFFFAQSNYNYERLQSTAFS
                     HSMLPVLKKLYPDKEELKQEVETHLAFFNTEPICGCVIHGITIAMEEEKANGADEISG
                     DGMNAIKTGLMGPLAGIGDTLTQGVITPIVLAVCIGLTEGGASIAGPILFVIAQYIIM
                     TSISFGMWTNGYKYGKKAVESILQGGIVNKVIEGASILGTLVMGGLVGRFINLSTPIS
                     YTSGDFKFSLQTDLLDKIFPGLIPLVLTLLVLFALKKGLSPIKIMFILIVVGAITGIL
                     GLF"
BASE COUNT         7144 a         2621 c         3349 g         7228 t
ORIGIN      
        1 tagtatatag ttacactaat ataaaataaa agtgcctcat aaatagaagt ttttgaggca
       61 cttattattt ggctaaatta gtttttatta ttttgtaata tcaaccgttt ataatctcga
      121 acattttttt tatatcttct gatgccattt caaattttga tttttcaatc agtatgtttc
      181 caccagtcat aatatatgat ggaaatactc ttaaattatc ataataaagt tcattattac
      241 gaagtttata tgttgaaatg gaagggatga cattcttttt tatatgcttt ttagtaatca
      301 tattaaaaga tttttttgca acatctccca ttaacattac tacctctagg tttttaaata
      361 atttaatttc ttcttctaaa ataggcatat gtaatttaat tgtatcacga gttattgtat
      421 attctgattt aggaagtttt actgcattag ttatatagat acccatatct aggatatcat
      481 ttatgttaga tacttctatt cctgcactgt caaataaagg aatagtagtt tttaaataat
      541 cagcatcttt atctacacta taaaaatcgt cattggtgtt agttgggaca acctcattaa
      601 tcattatagt ttttattttg tctgtttcta ttgttatatt aggaaggtag gatattattc
      661 tgttgtcatc aaaaagattg ttctgtttaa taaattcact taactttgat tttatattta
      721 ttttcatata acgagtctcc ttagttttaa gctttaaatt actataaaaa gctagtttta
      781 aagcacacaa ttttgaaaat atagtagcat atttgaaagt ataataacat ataaaacatg
      841 acaacagaat gtcatgtttt ataaataatc tatcgcaact tagaatttat tagagactct
      901 gcctgttcat aatcgtcttt atgaacataa attaagtact cataagagaa atcttccttt
      961 tgacctaaat tgccaagtgt tatttcatta aaaaaaggtt ttttagagta agcattattt
     1021 ttcactttat acttatattt aattttattt actgataata tattgcatat ctcgttaaat
     1081 ctatttaaag aatatcctcg gaaaagctca gttctattta aaatcataag gaaaacctcc
     1141 ttttaaaagt aatatattga aaagcatagg agaaatgtac tataagttgt tataaataaa
     1201 aggtagcaaa tttaaattga tttgtaaagt ttttaagagt attatattag tgataaaata
     1261 aataattttt ataatctaac taataacaat ttaaaatagg taacttatgt aagaatcgta
     1321 gggactacgg agatatcctg tagagaatta ataagacata tttaagtatg caaaattcta
     1381 ttaagtagga accttgtaac tttagtcatg tgagatttat aaggatattt aagtattgaa
     1441 aggagagttt aattgaaaaa aatatctcaa gaaaaaataa gtacacatat ccaagaagta
     1501 ccacaggaaa aaattgaaca gtggaaatct ttatatgaaa aatataaaag tattttaaaa
     1561 gtaaattcta agtctgtttt agaaataata gagtttttaa agcaaaaata tgtaatagta
     1621 gaagaaactt cagaggaatt taaacatgta gttatcaata atattaagtt aaacaagcct
     1681 ttttcacaaa agatttccag tgataaagaa ttaaaaccta ttgtatttac aattccaaat
     1741 gaaggaaatg caaaaaaatt gtacgatact caagaggaaa cttatagtgg ctgtaagatt
     1801 attgtaggta tggaatttga aacaggttgt gtttttgtag aaggtagtga tgagcttaat
     1861 gatgaaataa cttcttttaa aggattagat aaatatgata taagtaatta ttatttagta
     1921 gcaaactata ttagatgtct aaagaaatat aaattaatag attagtgttt gattaataaa
     1981 ttagtgcttg atttaaggat tatagagtaa atttgaagtt agtgtgataa tgaaactaag
     2041 cttaaatcta atataactgt aaaacataaa cttaaataga gttgccaaaa taaaattggt
     2101 aactctattt tttattttaa tttttattaa aattagtagg tgttatagaa ttgttatttt
     2161 ttcatgttag tattctctta gtaatagatt taaggtatta caagaaggga gaaattaata
     2221 tgaaagattt aattcttgaa acaaaaaact tatcaaaaag atatggagaa caaatggcag
     2281 ttaacaatgt ttctctacaa attgaacgaa atagtatata tggactttta ggaccaaatg
     2341 gagcaggaaa gtccacaaca cttaaaatgc ttgttggtct tcttcgccca acagatggtc
     2401 gtattatttt tgatagaaag ccttggaaac gagaatctct tgcaaaaata ggttctttaa
     2461 tagaatcccc tgcattgtat ggaaacctta cagcagagga aaatttgtta gtacatacaa
     2521 aaatattggg aatacctaaa gataaaattt atgaagtgtt ggaaatagta aatttgaaaa
     2581 atacaggtaa aaagagagct tcacaatttt ctatgggtat gaaacaaagg ttaggaatag
     2641 ctattgcact tttgagtgac ccagagttgt taatactaga tgaaccaacc aatggtcttg
     2701 acccctttgg cattcaagaa ttgcgtgaat tgattgcttc ttttccaaaa aaaggtataa
     2761 ctgtaattct ttctagccat attctatcag aggttgctca agttgtagat aatataggaa
     2821 ttataaatgg aggacgacta ctatttcaag gaatgcctga ccctaatgaa aatctagaag
     2881 aattttttac agatgttatt cttaaaggag gacaaaacag atgaatgctt tacaatcaga
     2941 acttttaaag tataaaagaa catttatggg taaacttatt gtttttttcc cagtgtcttt
     3001 tgcagcatat gcatttataa tgcaatcaac actcatgcaa aatccattat ctcaaacaac
     3061 ttcttgggcg tggcaaagtc ttttagcatt aatttttaac tggtggtcat ttttatttct
     3121 gcctattgga tttgcattgt ttgctacttt ggtagctttc caggaaaaaa aagctggaaa
     3181 ttatcgtgct ttacgtacac acaatgtgtc tcctatgaca ctttggatta ataaagttat
     3241 agctatggca gtctacagtt ttatttcaac gctagtttta atattcgtaa caattataac
     3301 tggtttaata ttgaaagctg gtccagttcc ttttggacag attatagggg caagtattgt
     3361 atgctgggtt gtttctcttg ctatacttcc acttcagcta tggctagcta catggaaagg
     3421 tatgttccta agtatgggag ttggagcttt aggcatgata tttggtgtcc ttgctgcgac
     3481 aaaaccattt tggattgcag taccttggag ttgggcagtt agaatggtat gcccaatcat
     3541 caacatacat cctaacggta ctgtattaga agctggagac ccacttttga atacttcagt
     3601 gattcctatt gggattgttg tttctttggt tgtgtttata gtattaacag cacttactgc
     3661 agcttggttc aataggaggg atgacaaatg ataaaactat tatcatcaga atggcttcga
     3721 gcaaagagga cagctgtcca agggcttact ctttgtatgc ctattatttt ttcattatgt
     3781 gtggttgctt atctcacaat taaatctgga agtacacaag aatttgcttt tgaaggattt
     3841 tttacagtat ggactgtatt catcattcct attggagtag gtattttagc aggatttata
     3901 gtgcaggagg aagagcttgc tggaaatttt aatggttttt tatgtgtagg tatttctcgt
     3961 gttagattat atctgggaaa atttcttttt cttctgtttt gcctaactat atgcacattt
     4021 attgctacgt tgatactctg cataggaatg agtattgcag tgccatctgg agcaacaata
     4081 tggttattcc tgtcagcagc aggacttgtg gtgattggga cacttccact attagctatt
     4141 catctttggg tgagttttgc atggggtatg ggtgcatcta ttggtattag tatcggtgga
     4201 attttgatgg cagcaatact tggattaact agcgttggtg aaaaagtatg ggcatttgtt
     4261 ccatggacat ggccagtaaa actaggtatg cttccaggga tttattttat taaagaagct
     4321 gaaactattt caactgaggc attttactct aaagtgatgc aaacagctag tatagagctt
     4381 atagtagtag caataggttt gattatattc ttgataggag gcgttatttg gtttaaaatg
     4441 tgggagggaa ggaaaagtta ttagtagaca aatattgttt taatactgac cttcccataa
     4501 gagaaaggtg gtgttatatt gagtaaaata ttgattattg atgatgaaat ggacctagta
     4561 atgctacttg aggacgaatt gaaggcaaaa ggacatgaag tgttgatagc ttatgatggt
     4621 caggcaggta tagagttatc aaaacaggag cctgacctta ttatactgga tattatgatg
     4681 cctaaaatga atggatttga ggtatgtcag gcaattagag atgatgtttt atgcccaatt
     4741 atatttttaa gtgcaaagca atcagaaact gacaaaatca aagggttgac ctttggaggg
     4801 gatgattatg taacaaagcc atttggactg cgtgaactta tggcaaggat tgaagctaat
     4861 ctgcgtaggg aaaagcgttc acagtatatc aatgaagaga acaagagatc tactttgtat
     4921 tttgggaagt tatgcttata tatgaaggaa cgtgcaatta aaattgatgg taagaatatt
     4981 gatttaacaa aaatagagta tgatattgtt gaattactag cactccatgc aggacaagtt
     5041 ttctcaagag aacaaatcta tgaaaaagta tgggggtgtg attctgaagg tgattcctca
     5101 actgttgttg aacgagtaaa aaaaatacga gctaagtttt ctgctgtgac accagaaaaa
     5161 gaatatattt ccacagtttg gggtattggg tataagtgga ataaaatgta aagagagaga
     5221 ggttattaaa tgaaaaatca atcccttatt gcccaattta gacatacttt tatttttatt
     5281 ataatagcca gtatagttgc cacagtgatt acttatgtat ttgctattta tttgtatatt
     5341 tattccttaa ataaggatat ctatccacca aactattatg agcgacaagt tcctagaatt
     5401 gaaaaataca tcaatgaaaa aaacatagct ttgttatcac aatcgaatga agaaggttta
     5461 aaaagaacga ttcgtgggga tgatatgcta tatcaagttg tggataataa tggcaatatt
     5521 ctatatggta ctaatcccaa aaaactattt aaaacaaaag aagaattatt taataatttt
     5581 atcaataaaa ctgttcgtaa aggtggttat atccatactg ttccaatcaa aggggataat
     5641 ggaaagattg agggagctgt tattctattc tatcaagtca aaataacctt tgcaaatagt
     5701 agagggagat ttgtatttgc agttattata atggctctgt tttctccatt tctatatatc
     5761 gtgggtttta ctagatggct ttctaagcgc tttgtaaaga atatcaatca accattacat
     5821 ctattgattg atgcgtccaa gaagataaaa gaaaaggacc ttgattttga aatcgactat
     5881 tattcagata atgaactcgg taaactttgt agtgcctttt ctgaaatgaa agacgaatta
     5941 aaaggttctt tatctgcgca gtggaagatg gagcaggaac gtgttgaaat ggtggaagct
     6001 ctagcacatg atttaaaatc tcctctttct attattttgg gatatacaga tgcacttatt
     6061 ggtaataata cagatgacaa tgaaaaactt cataggtatc ttacagtgat aagagaaaat
     6121 acagaaaaaa gtgttgctct tgtccaaaag atgcaatata cgtctgactt agaaaagtca
     6181 aatatacaat taaatcttgt tcctataaat ttacctgaat ttttgaggca aaaggtgcaa
     6241 gactatgaat tacaggctca tcaaaaggaa gttgaactta tattgaaaat gcaggggaat
     6301 atacaatccc caattcaaat cgacgtggat aggttgacac gaatttttga taatatcata
     6361 tccaacagtc tgcaatacac tccatcaggt ggtaatatta gtattactgt aaaggatgaa
     6421 aaaaattgta tttcttatga gatttgtgat tctggtagag ggtttagctc taaagattta
     6481 aaaaaggctc ttgataagtt ttatcgagga gatgaagcta ggcagacaaa aggtggacat
     6541 tctggtcttg ggctttacat tgtcaaacaa ttagtggaac agcttggagg ttctgttaaa
     6601 atagaaaatt caaaatcagg tggagcatgt gtgaaatttt ggcatagcat ttaactatat
     6661 attttaaatt aaaggggagt gtctcaaagc gaaattttta attcgtgagg cactcttttt
     6721 ttgtgaagtt aaatatattt tcattattcc gacaatgaaa aaaggcttat ctctattttg
     6781 agacaggcct tttttaaagc ttatattata gttaaaaaga tttattagtt agatttgaaa
     6841 gaaaatagag acagtcattg ataatttaat ttatattatt atctgtaaaa tagttataaa
     6901 ttgatatcta tacagtcaat tatattcatc tttttaactt ttcttaacgg aataagagta
     6961 gctataatac atgcaagtac agaaataata gtagcttgta aaattgaagt aattggtata
     7021 ttagtgaaat caagcttttc tatagttgcc atgtttataa taatagcact ggcataccca
     7081 gcaattgaac caaatatagc agcaaaaatt ccataataaa caccttccca taaaaacatt
     7141 ttatataagc taatattact cataccaata gctcttttaa ctccaatctc attagtccta
     7201 gtatttatat ttgtatgagt tgtgttaatg atgtttaaag taccaatcaa tcccacaaat
     7261 aatataactg cccatgctag aaattctatt tgtttaaaac tctctttaag ttgcttatct
     7321 gattcaatat atgatatcca atgagagcca ggattatttt cacaaatctg ttcaatagat
     7381 aatcttattt gttctaattt tgatttatct ttagcataaa tatttatctg gttgaacttg
     7441 tttttatttg tcaaggtgtt ataaacagaa tcatatacaa taacatcaac accatttatc
     7501 cagccattac cttgtaaaaa gaacatttta tctactgtac tatatatatc tagttgtttt
     7561 ttgttgattg tgatactatc tttaggtttt aaatttgtat gtctagtttt tacacctggt
     7621 gtagaaatag caatcggatt ttttataaaa cagatagaac catttttaaa gtcttctagt
     7681 atagaatctg taatagaagg cattaaatct tttaaagtct gctcgtcaat tccaatgatt
     7741 tttaacatct caccactatt ttcaaaattt atatctgtat ctatttcacc ctgtttgtat
     7801 tcagagtact ttataaagga agtgcgattg acgtttttca ttttatctat tttatctagt
     7861 gttgatttat caaaaccaga tatttcattt gttaaggaaa aatctccttc ttttaaattg
     7921 cttactgacc tagatacatc taatacatta gagaactcac tcaatgcaac gaatactgtt
     7981 atactcataa ataatgatag tatagttatt atagttcttc ctttatttct ttttaagttt
     8041 agccatgcta gatgtctttc aaagtttttt attgcttttt ctcttttaat ttttcttttg
     8101 attttggtag tactaccagc catagcaatt ttgggagaga cacgtgaagc atatattgct
     8161 gatggtaatg ctgaaataaa tgaaaaaatc aaagatacat tagtgcttaa tactaatggg
     8221 aacatatatg ctgttgtatt tttatgtata agctcagtaa tttctttatt atcatttgct
     8281 agaagtatat ctggatttaa gatattagtg accattccag ttatgccttt agaagagata
     8341 attccaatta cagctccaat aggtatggca acagtacata aaattaagat ttgtaaaata
     8401 actatcttat atatctggtt tggttcagct cctattgctc ttaaacatcc atactcttta
     8461 attttctttg taacagagat ttttaaaata ttatagatta caagtccaga agccagtaaa
     8521 accaataagg caacaaataa agataccaat ataatcatag atataccatc actattagaa
     8581 ctattttcat ctttttcaaa ctgtatctta agagcattta agtaaatcca attatattga
     8641 attgaattgt gagaaagatt tattttttta gctaattgat ttactatttc ttgaaacttt
     8701 tcttgctgtt ttattttaaa atccaaagag gataaaatat atctcttagg taatagattt
     8761 tctgatgtac ctttacctac aataccattt actataccac ttacatatcc tgtataatca
     8821 tcctctaaaa tgccactcaa tttaaagtta gctgtgtaat tatatggtgg tatggtatca
     8881 tttaaaagtg aaatatctaa attcataggt atagtcactc ctagtcttgg ttttataccc
     8941 ataagcttta gagtgttttc atctaaggct atttcgtttt tatctttagg caaatgtcca
     9001 gattttaatt tcattaattt tgggtagtta gaaagtcctg ttttatcata ctcttttaca
     9061 agtacagaga taccagaatc ctttatttta ctactgccaa tagttattga agtaccagct
     9121 tgataaactc tatcatcttt ctttatgtca tcaacttgat ttttagtaag ttggtgaaag
     9181 gatacatgtc tatcaccatt aaaagaacgg gcttgttcaa ttcttaaatt ttgtaggata
     9241 ccaattgact gtccaaccac agttgtcata atagttgata gtactattgc tataatgatg
     9301 aatgtagtca taagtttctg gctttttaat tcttttattg aaagtgaaag gtaattcttc
     9361 atttctattt cacctccata agaacaccat caataattga aatttttcta tcagcaagtt
     9421 ttgcaattct atcatcatga gtaattacca ctaaagtctt tccaaactgt tttgaagttt
     9481 ttataagaag attcataact tcactgccac ttttactgtc caagtttcct gtaggctcat
     9541 cagcaaatat tatatctggt tttgcaataa gtgctctagc aattgcaact ctttgttgct
     9601 gaccgcctga aagttcatgg ggaagatgat tgagtctatc tgcaattcta agtaatgatg
     9661 aaatttcatt taaatagtct ttatcaggtt gttttttatc tagaagtaca ggcattgaaa
     9721 tattttcaga tgccgtaaga acaggtaaaa gattaaactg ttgaaagacg aatccaaagg
     9781 attttcttct aagtgaagat agttcttttt cagtgtgttt atatatatct ttatcatcaa
     9841 gtaacacttg tccagaggta ggattatcta atccacttaa aatatgtaaa agtgtgcttt
     9901 ttccacttcc agaaggtcca attatagaaa caaattcacc tgagtttatt tctaaattta
     9961 cattattaag tgcgataact ttattgttat tagaaccata tatttttgat aattgttttg
    10021 cttttataat cataaaaaac actctccttt tctatataag aagagtgtaa gttttaaaac
    10081 tcaatttttt cccaattttt aatttaaatc taaaaagtct tcactattta cggataattc
    10141 gcagtgctga taagcagttt cagtatcatt tttaatttaa aatgtaattt atgcactaaa
    10201 ggctttacaa tacaactcta ttgctttaaa actattttac acataaactt gtggataatt
    10261 ttttatgttt tacttcctca ttattatata aattattttt gtcacaaatt ctaagttgtc
    10321 acataaatat actttttata tcacgattta attcttttga ttttatcata attgctattt
    10381 cttcaaaaga agaaagaaaa gccacgatac atatcataat tcctgcaaca tcaagaccaa
    10441 agcaaatata gagtaatgga aaagcaaaga tagaaattcc agtgatttta ttcattaaag
    10501 tatgaagcga tgaaaatgtg tgatacttaa aaaaaccaat actgtaacta atcaaccgta
    10561 ataatgctat tgcaacaata caccaccata gatacatggg aagagcaata ttttttccga
    10621 cagtaaccaa aattgtaacc gcaaaaatga aatcagcaat actatctaac tttgcaccta
    10681 ttccactttg ttgtctcaac tttcgggcaa taagaccatc aagtatatca ctaattccac
    10741 accaaaaata acatatccag aaaggcagtg aacagaatgt agaactaagc attagcaatg
    10801 caaacacaat acgagagaat gtaatattat tagcaaaact tttaatataa tcacctccaa
    10861 aattctaatt tcatactatt ctacatattt aaatatatat ttctattatt gtttcaaatg
    10921 ccttttgcca aaatattata attgaagcaa ctcttacaac ttctacaaaa tagtatatat
    10981 attggttgta aattgaaata cattttataa attctaaact aacaaagctt atataagaac
    11041 aatgaaagct tacaaaatca ttttaatttc ttgttgagaa tttagcagta attttagcac
    11101 tgttagtaga attattttca atagaaatag agccaccatg tttttcacat aatatttttg
    11161 agatataaag acccatacca aagtgtggat tgctgtcatt taaagtctta tctctataga
    11221 aaggtcttaa agctaatttt agagattcct tactaaatcc tataccatca tcttcaatta
    11281 caaaggtaag gagttcttgt tcaagatata taagtatgga tacattattt ctagcatatc
    11341 taaaagcatt cgatattata ttttcgacga ctctaagaat gatattttca tcaaaaaata
    11401 gatttatatt atttatttga cttttaagtg taaaagattt tccttcttgt ttagcaatga
    11461 tagatatatt ttcatctaag ttttctataa acttgtttat attcgacata gattttgaaa
    11521 caactaaatc ttctaatcgt tgagcattac tcatattttc tacatagtat tcaattctgt
    11581 taatatgctc agacataagt tgtgtggttg ataaaatctt ctcatcacta agtttacctg
    11641 ttggtatgta ttttgttaaa tagtttgagt aaccttttag aactgttagg ggatttctta
    11701 aatcatgaga aaaagcagca ttaagttgtt ttctatcatt aatcatagtc cacatattta
    11761 tgttgttttt atttagttca gacctcattt tttcaaaagc attacataga ttacctaatt
    11821 catcattatt attatattct aagcaaaagt ctaaattgtt gttggatatt tccattgcac
    11881 ctttattgag gatttctatg ggtgttttta attttacctt gtaaaaaatt atatcagcta
    11941 ataataaaag tcctataaaa aatataagtg gaagtacaag ctgaagtatg ttgattatat
    12001 taagtaatgt tttatcataa tcactaaatt ggttcacatt gttttgaact atggttataa
    12061 tacctgtatt tataggtgtt tttaaatact tatcttgtat agaattatat agattattaa
    12121 gtaaaatgta tgcgaaagta gtaagtactg atgctataat tagtgaagat aaagtaagaa
    12181 caaagaaagc tttttttaat gacatattat ttattttatc catttataac caactcccca
    12241 gactgtttct atataatttt caagagtatg ttttgatagt ttgattcgta tttttctaat
    12301 gtgttccatt ataacatcac tatttccatt gctattgtat ccccagactc tatcatatat
    12361 tttttcttta tcaaatacct gtccaggatt catagagaga agctctacta tatcaaattc
    12421 cttttttgaa agtgaaatct gattattata tatacaaatt aacctttttt cgtaatctat
    12481 tgttaaatca ttataaaatt taattttagt ttgatttgac ttcctttgtt cacgtcttaa
    12541 atgtgcagat actctagctc caagttcgtc taaatcaaaa ggttttacaa tataatcatc
    12601 agcaccagca cgaaaaccat ttatcttgtc agtattttca attctggctg taagaaatag
    12661 aatagggcat gatacataat ctctaattct attacaaact tcaattccat ctatttcagg
    12721 catgtttata tcaagtagaa tgatatctgg atttttggat atttttttta atgagtcttt
    12781 tccactttga gcagtgtaaa cctcataacc attcatttca aagtaatctt ttaagagtgt
    12841 tattatacct tcctcatcat ctacgacgag tattttattg ttcataagaa tgctcccttc
    12901 taaattaagt ttgtatagta tttatatttt agtataaaaa tctcaataaa ttctcaaatt
    12961 cttagttata tttcaaaact taatcattaa agttagtata tttttatata ttaaataaat
    13021 caaggatgaa attattagaa attttaatag aatatatatt taatatttat tggaatgcaa
    13081 aaacacagct gatgaaatct tataatttaa gttgaaaatg gataaataga aaggaaggat
    13141 tttaattaaa aaggtagatt aattaaaaag tatataaatt ataaaaatga attaatctac
    13201 attaattagt tgatatatca attattatta ttttttcagt tgcttaaaat atacttgata
    13261 tatcaactaa tgttgttttt taattaaaag aaattttagg aaagataata ttaactagga
    13321 gagataatat caacattgaa gaaggtagag caatattttt acataattgt gaacattatc
    13381 tggcatgtgt gcattggtgt tttaagcaag caattcaata gaaagatgtg actaaaaata
    13441 gaaagaaata ccataatcca catgtaaagc tagaagacat aataagtaaa aaaagtaaag
    13501 atatttaata aaagaaataa ctaatagtga ttaaattagt aaatgctgac aattagcata
    13561 atcattagta attattagta ttatttaatt aaattaattt tagcattatt tttattaaat
    13621 taattttaaa tcaaattaat gagaacccca taaatttttt taacacttaa tttatgattt
    13681 atggggttat gttctgtttt atttcaaagt attaagttca tataaatcag ttcttctgtg
    13741 cttaagaagt ggtaactgtt gtcttatgtc aggaattaaa tctctatcaa tgtcagcata
    13801 aataatacat tctttttcat cagcttgagc aattattctt ccccaagggt ctgaaattct
    13861 tgaatttcca aaagctatat aagaagcatt catatttcta gcaggtgcag caccaacata
    13921 gaatatctga ttatctaaag cacgcattct tatagataac tcccaatggg cgggaccagt
    13981 agtcatatta aatgcagcag gtaagataac gatttcaaca cctttaagag ccattaaacg
    14041 tgataactca gggaaacgaa tatcatagca aatagctata ccaacttttc catattcagt
    14101 atctattaca gtgacatcat ttccagctgt aagagtatct gattctttaa aactaacttt
    14161 tcctgtaact tcaatgtcaa ataagtgcat tttacgatgt tttccaatta gagctccatt
    14221 tttatcaaat acatagcaag tattatagat ttttccatat tctaactcag gaatactacc
    14281 agaaactaga taaattccat gtttctcagc taatttactc aatatcgttg ttgtttcacc
    14341 tggatattct tcagcaaatt taggaaaata tttattttca tatgggcagt taaacatttc
    14401 tggcaaaact acaattttag ctccattgat ggcagcttct gttaccatat ctacagcatg
    14461 attgatattt tcaattttat tttctgtggt catcatctga catactgcaa ttttatagaa
    14521 attcatagaa attactcctt tcaatatttt tatgttatta taacatatta aataaaaatt
    14581 agatattctt agatttacct aaatgggtat ggagagaagt gaataagaat attaaaaggt
    14641 atataaaagt tatttttatt atagatggaa cccatatatt gacttttttt atatatgttg
    14701 atagtattat tatagataaa atagaataat taatagagtt ttatagggtt ttgcaattat
    14761 taatgattgg cctggtccga gataaaaccc acaacatagt ttttgttgtg aacacggaag
    14821 gacaaaaacc tgggagatat tttataatat ttctcaggtt attttattgg aaaaataaga
    14881 gatacatttg aaaagaggga tgagtttatg aaatggttat ttttgtttgt tgcaggtttg
    14941 tttgaagtgt tttgggcttt tcaactaaaa aattcacatg gattttctaa attaactcca
    15001 agtatactta ctgttgttgg aatgattgta agtttttatt ttttgtcatt agcactaaaa
    15061 catcttccac ttggaacttc atatgcaata tggactggaa ttggtaccgt cggtacagct
    15121 attgtaggca tggctatctt aaatgagcct attagtatat caagaattgc atgtataggc
    15181 tttattgtgg tgggaattgt agggttaaag ctattatcta ctaattagag tatattaatt
    15241 taaataagct atgaaattaa aggcgagaaa atgtttaaaa ataatcaaca tttaaaaagt
    15301 ctttacttca tagcttatct tatttataag tttattatat ttgaaaatta tatgtatata
    15361 ctatttatct aataaaagag cagttaaatc catagggtca actattacac catctttata
    15421 aacacgcata tttccagatg ctatttcatc tattaagatt acttcatcat tgtagaatcc
    15481 aaattcaaat ttgatatcat aaagttcaag acctttttca gctatagtat cacgaactat
    15541 attagaaatt ttttgagtca tgcttttcat tgaatcaaat tgagcttgag tcataatgtt
    15601 taaagcttct aaaccttcag atgttataag agggtcacaa cggtcatcat cttttaaagt
    15661 tgcttctaca tagcaatcta gtttagcacc ttcttcaaca catgaaccat aacgacgtaa
    15721 gaaactacca acagctctat aacgacaaat aacttctaat ccattaccaa aaacttttgc
    15781 tggtagaact tccatagttg cttcttctaa attagcactt acataatgag ttttaattcc
    15841 agcattgttt agaatttcaa agaacttaac agatgtctct aaattagctc taccaattcc
    15901 atctatactt agacctacac tattttcgcc tgggtcaaat actccatctt taccagttac
    15961 atcgtcttta aatttaagta agtaatttcc attatctaat tcaaaaacat ctttagtctt
    16021 tccttgatac acttttttca taaacaacct ccaaaaagtt aaattattat attgaataag
    16081 gcattagtgt caaaaaagtt ctgatattcg catgaaaatt tatattgata ccttatattt
    16141 aatattatat cacaaataga agggaaattt ccgaacaatt ttataaaaat aacaaaaaaa
    16201 gtacatttta taaaacttat aataagagaa ctaatataaa atgttagtgt cgtttatatt
    16261 gacacacata agttttaata taagaaactt ttgacacact ttgacacaca tttaatgata
    16321 attttataaa atgcatgaat acaatgctta catatattgg catgaaagtt gctttagata
    16381 tttaacatat aaacaataag tatatattct caaataaaaa gtaggggtgg ttaatagtga
    16441 agtcagttag attctatggt ataagagaca caagagtgga ggatgtggat gtaccaaaaa
    16501 tattagaaaa agatgatgta ataattaaag taaaagtagc tggaatatgt ggttctgata
    16561 tatcaaaata ttcaaagaca ggtccacata tggttggaga aattttaggg catgaatttt
    16621 ctggagaagt ggcacaggtt ggtaaagaag taaggagttt taaaatagga gatagagttg
    16681 ctgtttgtcc agctatgcca tgttttgaat gtgatgaatg taaaaaagga ttgtattcaa
    16741 gatgtaataa tgtagcaata ataggaaata aagaacttgg aggttgtttt gcagagtata
    16801 caaaggtgaa agagaggaat ttaataaaaa taccagatga gataagttat gagactgccg
    16861 ctgcgctaga accagtatgt atagcagggc atggtctttt tagatcagaa gctaaagttg
    16921 gagatactgt tgtagtactt ggtacaggta caataggatt attttcaata caatgggcaa
    16981 agatatttgg ctctacaaaa ataatagctg tagatgtatt tgatgagaag ttagacttgg
    17041 cgaaagagtt aggggcagat atttgtataa atgcaaaaga aaagaatatt gtagaagaaa
    17101 taaaaaggtt aactgatgga gatggtgcag atattgttat tgaatcggct ggtactccaa
    17161 tgacatgtgg gcaagtattg ttgttagcta aaaagggagg gacagtattg tatgcaggtg
    17221 taccatatgg ggatgtagct ttgactagag aacaatttga aaagatagta agaagtgaat
    17281 taactgtcaa gggaacttgg tttggaaact cctttccatt cccaggaaaa gaatggagtg
    17341 ctggattgta tcatatgcaa aagggtgata tgaatgttga aaaattagta acacatagaa
    17401 taaatttaga agaagtacca gcttattttg aaaaagtata caaaagggat attttctttg
    17461 gtaagataat gattaatata gataattaga ttagagtact aaataataat ccatataaac
    17521 aaggttaaga aaggtatgat tcatatgaca gggataatta tagccacaca tggaaatatg
    17581 gctaaagcaa tgttagaaag tgctgaatta atagtaggca aacaggaaaa tgtagaaact
    17641 ttaggattaa accatggtga cagcatagat gagtttagta gaaggttaga agatagaatt
    17701 gagaaatata aggatgaagg ggttttagta ttgcttgatt tttatggcgg gactccattt
    17761 aatacatctg ctattataat aaataaattt gctaaggtat gtgagttaga atgtttgaca
    17821 ggtgtaaatt tacctatgct tttagagcta tttttaaaca gagatactat gaagttaaaa
    17881 gacttgaaga atttatgtga ggaagttggg atatcaggaa tcaaagatgt taaaactgtt
    17941 ttaaagttgt aaaataaatt aaaaatctgg aggaataatt atgagtaata tagcattaac
    18001 aagaattgat gatagattaa tacatgggca agttattact gcttggtgta agattacatc
    18061 ggcaaaaagg atagtaatcg tggatgattt agtagtaaag gacccattta tagttcaagt
    18121 tttacaaatg gcagctccat caactgttaa ggttgaagta catgatgtag aatcaggtgc
    18181 tgaagtttta aaatcacata atggagatga acatttaata gtattggtca aataccctaa
    18241 aactgtctta ggtttagtaa atagtggggt agatttaaag gaattgaatg ttggaggtat
    18301 gggagcaggg cttggtagaa aaagttttta taaaaatata tctgtgtcag atgaagaaaa
    18361 agaaatattt agagaactaa tatcaaaaga tgttaaatgc tttatacaaa tagtaccaga
    18421 tgcaaagaaa attgatgtag gaacattatt ataaaaaaga ctatcttgta aatctttaaa
    18481 agaaaatagg gaggaagaat atgcacattt cactaattca agcagtatta atagcaattt
    18541 tttattatct ttcttggagt ccgtggttga cctatgttgg attttttaca tggaatagac
    18601 ctctattggc tggatttgta acgggaatta tattaggaga ccctgttcaa ggagcaatta
    18661 taggagcagg tataaatatg atatatctag gttttatatc agcaggggga gctcagatgg
    18721 gggacccagc ttttgcagga tatgtaggta ctgctttagc tatagcatct aagctagatg
    18781 taagtactgc aatggcaata gctgtaccat tgggaactgt tgcaactgta ctttggattg
    18841 gaaagatgac agtaaattct ttttttgcac attgggctga tagagaggtt caaaaaggga
    18901 atgttgatag agtagcattt ataaatatag taccaccaca gatactgtta tttgcaatga
    18961 gttttatacc agcattatta gttgtttatt ttggtccaaa tgcgatagat ggtatgttgg
    19021 aagtaatgaa tgagaatgtg ttacatgtat ttaatgtaat tggggctatg ttgccagcac
    19081 ttgggattgc tatgaattta aaattgattg gaaacaagtt tactatgccc tttttcatat
    19141 taggaatact aatggctgtt tattttaaag tagatataat agtaatatct gttattggag
    19201 taatacttgc tcttacaatt acttcaatta agtacggaaa agatagtgct acatcttaaa
    19261 tacatgtgag ggggaaaata ttatgtcaga tataaaaaat gaagtatcta agaaaacgtt
    19321 aagcaaaaaa gatgtaataa aatcatggtt aagatggttt ttctttgcgc aatctaatta
    19381 caattatgaa agattgcaat caacagcttt ctcacattca atgttgccag tacttaaaaa
    19441 attatatcca gataaggaag agttaaaaca agaagtggag actcatttag cattttttaa
    19501 cacagaacct atatgtggat gtgttataca tggaataaca atagctatgg aagaagaaaa
    19561 agctaatgga gcagatgaaa taagtggaga tggtatgaat gctatcaaaa caggcttgat
    19621 gggtccacta gcaggaattg gtgatacttt aactcaagga gttataactc ctatagtgtt
    19681 agctgtttgt attggtttaa ctgagggagg agcatcaatt gcaggtccta tattatttgt
    19741 aatagctcaa tatataataa tgacttcaat ttcttttgga atgtggacaa atggatataa
    19801 gtatgggaaa aaagctgttg aaagtatact tcaaggtgga atagtaaata aggttataga
    19861 aggggcttct atattaggta ctttagtcat ggggggactt gtaggtaggt ttattaattt
    19921 atctacacca ataagttata ctagtggtga ttttaaattt agtcttcaaa cggatttact
    19981 tgataagata tttccaggat taattccttt ggtacttact ttattagtac tctttgcttt
    20041 aaaaaaaggc ctttctccaa taaaaataat gtttatactg atagtagtgg gagctattac
    20101 aggtattttg ggactatttt aaataaatat atatgttggt gtgtaaatta ggattctata
    20161 tctattgatt atatttgtaa gatgttggaa aatttatatt aaaaagttta gcaattaggg
    20221 taattttata atagattaaa ttttaaactt atataagcta tatatagtat ttaatatttt
    20281 aaaaagtatc tcagaaagat ttttaatcag aatgaggtgc tttttcattt gcatataaaa
    20341 ta
//
LOCUS       DACTZW010000078        19341 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.078, whole genome shotgun sequence.
ACCESSION   DACTZW010000078 DACTZW010000000
VERSION     DACTZW010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19341
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.078"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            299..688
                     /locus_tag="JAM15_14570"
     CDS             299..688
                     /locus_tag="JAM15_14570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HAT6799477.1"
                     /translation="MKINKLPHAELKLMKYIWGVDDVLASRDIIETMKLKYDWKKSTT
                     LTFLKNLVDKGFLTTDKVDRCTHYTIAIKEKDYLKVETKSFFSFMHNNSFKSFISALH
                     DDEVLDSKSLDKLEEYFKNLKEEDIDD"
     gene            1010..1519
                     /gene="vanZ1"
                     /locus_tag="JAM15_14575"
     CDS             1010..1519
                     /gene="vanZ1"
                     /locus_tag="JAM15_14575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ1"
                     /protein_id="HAT6799478.1"
                     /translation="MKSRKHNITKGLFIVYIIVLTWIILFKLQFDISSLETMNLRSIN
                     LVPFAGSLIINNRVDISEIILNVVIFVPFGIYVCMLKEKWSFIKKVIPIFITSLAFET
                     LQYIFALGASDITDLIGNTLGGIIGIAVFMLLSKIFKNNAIKIINVLALIVTIIVVLF
                     LGLVIFANL"
     gene            complement(1621..1815)
                     /locus_tag="JAM15_14580"
     CDS             complement(1621..1815)
                     /locus_tag="JAM15_14580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase"
                     /protein_id="HAT6799479.1"
                     /translation="MSVIVMCSRCGKEIDKYRNKYITYYEKNTNAEIKVCINCALDLL
                     EKTRENQELNIQEFQDTIIL"
     gene            complement(2335..2727)
                     /locus_tag="JAM15_14585"
     CDS             complement(2335..2727)
                     /locus_tag="JAM15_14585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAT6799480.1"
                     /translation="MAALKSFEKPLTPEEEIEYLTKFKIENDKSAKDTLIERNMRLVA
                     YIAKKYNNSTEDQDDLISIGTIGLIKAIETYNIDKGTRLATYASRCIENEILMNIRSN
                     KKNKTQVSLQDPIGTDKEGNEINATFYM"
     gene            3295..3657
                     /locus_tag="JAM15_14590"
     CDS             3295..3657
                     /locus_tag="JAM15_14590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799481.1"
                     /translation="MKIRKSGFISIECIISIAILYVAVYLVSTSLYNCYSFISRNISD
                     REMLSTAKKYIEDEKYRIQNSKYELIEDKIEKNYINGYEINSRIEQILDYYQCYEINI
                     EIKNEFKKLRFNSYVTRK"
     gene            3641..4357
                     /locus_tag="JAM15_14595"
     CDS             3641..4357
                     /locus_tag="JAM15_14595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799482.1"
                     /translation="MLLENKGSILIITLIIFSIISTVCIMCIGLIYTHNNMFELGYKD
                     IQLKEISLSGIEISVSNVLSCVEEAIDVSNNEDEFREYFLGNNMIECIKKIKDTSYSS
                     LEELSLKVENNTIYDRGDFFEFDIESNVREKEFLKAIKVRVKIKNPWIGIDIEDYMDK
                     SNNNKIDDKTFNNYKASENNEILNQFKNESENIRNQEVVEFTEEDEEYEEELKQNIIE
                     NIKKNFDEKKLVQVYKYRGV"
     gene            4377..4796
                     /locus_tag="JAM15_14600"
     CDS             4377..4796
                     /locus_tag="JAM15_14600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799483.1"
                     /translation="MTVIELIVSISIILLIVTLSFPKDNLENHKINLFARQLCSDIRY
                     VRRINMFSNYNTYIYYINQGKYEGYVLRKDGKNIKSIMLPKNAKIARSIEIIKFKSDG
                     SPQKASTIEIYNNRLRKTITITPVSGRVLLKEGKYET"
     gene            4786..5310
                     /locus_tag="JAM15_14605"
     CDS             4786..5310
                     /locus_tag="JAM15_14605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799484.1"
                     /translation="MKHKYGYLLLESVVSLSSMVIIILVLYSIFLSTINLKLKVEDKI
                     ELQQQSLEIIKSMEGIISNSMGIMNVSNYEETFKKTTSIKCRYVDENNNEESISNKEI
                     ILNERRNKLFVNSLNGESSQAGGYEIGDYVDEMYVLITNNGQYVNIKLKLSKRSQKYE
                     TDFKIKVWNFSESI"
     gene            5622..6179
                     /gene="efp"
                     /locus_tag="JAM15_14610"
     CDS             5622..6179
                     /gene="efp"
                     /locus_tag="JAM15_14610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007287307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HAT6799485.1"
                     /translation="MVSAGDFRKGVTFEKDGQPCLVVDFQHVKPGKGAAFVRTKYKNL
                     KTGAIREESFNPSEKFPKAVIDTRQMQYLYNDGELYYFMDQENFEQIPLNYEQVEDAI
                     KFLKENEVATIRFYQGQPFQVEAPNFAELEVTDTEPGIKGDTASNVTKAATVETGAVV
                     QVPLFINTGDKVKIDTRTGEYLSRV"
     gene            6271..6726
                     /locus_tag="JAM15_14615"
     CDS             6271..6726
                     /locus_tag="JAM15_14615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HAT6799486.1"
                     /translation="MKHLYEEVAYLKGLAEGLEISAESKEGKMIHKIVDALEVFADAI
                     VTLDEEQEELQDFVESIDEDLADLEEDIADMEEDLYEEDDDEDDEDFSYIEMECPNCG
                     ELVEIDEDLLYDDEVDVVCPDCKAVILSSEDDCDDDCTCGGCSSCDDRE"
     gene            6889..7599
                     /locus_tag="JAM15_14620"
     CDS             6889..7599
                     /locus_tag="JAM15_14620"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HAT6799487.1"
                     /translation="MKISKKLLDNIQRFENVINYKFKNKEYILEALTHSSYSNENKKY
                     NFNERLEFLGDSVLGIVISDYLFNEEANLPEGELTKLRANIVCEDSLSEVANDINLGI
                     HMLLGRGEEATGGRHRTSILADAFEAVIAAIYLDGGFESARQFILHHMENIIYDSRKG
                     NIFRDYKTHLQEVLQGNGENNIWYRLIEEKGPDHNKRFVMEVGINDDVLGIGEGKSKK
                     EAEQLAAKIALKKKLWEK"
     gene            7653..8723
                     /locus_tag="JAM15_14625"
     CDS             7653..8723
                     /locus_tag="JAM15_14625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HAT6799488.1"
                     /translation="MKKRIIPIFVPHKGCPHDCIFCNQKKITGVSTDVTSEDARNIIE
                     ECLETIDKDADVEIAFFGGSFTAIDIDIQKSLLSVAKEYVEKGLVKDIRMSTRPDCID
                     EDILSMLKEYKTSVIELGVQSLDEKVLLDSIRGHQSEIVYKSSKMIKNSGIKLGLQMM
                     IGLPADTEEKCIFTAKKFVELKPDCVRVYPTLVVKDTGLEKLMEQNKYNPFTLEESVN
                     IVKKVLVLFYVNNINVIRVGLQATDDIQIGKAVLAGPYHPAFRELVEADMIKDYLEFV
                     ILQNKNIKQMLVKSNKKNISKIIGNKKTNVKYMEEKFGVLLKTQESDLDINQLEIVLD
                     GKSLISANMRDIHRKLYDIYDL"
     gene            8751..12305
                     /gene="smc"
                     /locus_tag="JAM15_14630"
     CDS             8751..12305
                     /gene="smc"
                     /locus_tag="JAM15_14630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HAT6799489.1"
                     /translation="MYLKRLELKGFKSFPVKTDIIFKEGITAIVGPNGSGKSNISDAV
                     RWVLGEQSIKSLRGDKLEDVIFAGTDTKKPMNYCEVALTIDNSENQLELDFTEVTIRR
                     RAYRNGESEFFLNNKSCRLKDIKEVFLDTGIGKDGYSIIEQGKVDEILSNNPLSRRKV
                     FDEACGISKYRYKKQEAERNLSNTKENLERIDDVYIEIENQLKPLFNQQTKAKKYLEI
                     SEKLKILEVNSFIREIEGIEKELSEVNEHRKVIEKELNEKEEQKNVVEKKQEDINKEV
                     EVLQDVIEKSVDYINSIKGVISKKESQINLIKERIRNFTNEISRKNLEINDIKEKLNE
                     NKQYIKELESNKLSGSEELSTLQENIKVLEASKDKQKIKLESLNNEIELLKESIIDIL
                     NKKQEFSNKLSTLNANKENMNIRDENINSEITELNKNIEIKSSELDTINKEFNMQNEN
                     LKNVNNRHKELSINLQDSISEHNKLEDEIQKSKYNLNGYNSKLNVYIDMENHYEGFNR
                     GVKEVLKNKNLKGVHGALGQIINVPEKYEKSIEAALGAYMQNIITDNEFSAKSAINYL
                     KQNNLGRVTFLPLNIIKSNKVSLGNLKANTKFIGIASDLITFDEKYRNIIENILGRTI
                     LINNIDEGIKFAKETGHRFKIVTLDGEILNPGGSLTGGSLKTNGNILSRKRYINEYTE
                     KISNIKNEISHLELKRESLDKDVKNIKNEIDSHESKIKDLEKSIIIKSTSIKNVESEI
                     ESLKGSITKLENEKNDLNSNLNYTLEKSDDVRKDMEELDDLYNKNKEKIDALNEEIKR
                     YNDLYDKEKSEFDELNLSLVKKTEAYNSIVRDIKRISGENCELEEKNKQLEESLNYEE
                     HEIIKLQDSIATEEKEKENLTKQLGDSNRNLETRKIAKDDLKNSFDEINKELKTIDRQ
                     HIELKESLFKVGGRLERLKTSQDTYINKLFEQYDMTLVQALEIKDEDLDIDRKFLESL
                     KREIRSLGNINIDSIKEYEEIKERYDFYSEQKQDLEESMEEIEKLIHTLEENMKSEFE
                     IKFEEISKNFKYVYKRLFGGGCGELTILDKENLLESDILITAQPPGKKMKNLNLLSGG
                     EKALTAISILFAILITKPTPFCILDEIEAPLDDANIFRFGEFLKDLSKETQFISVTHR
                     RGTMEAADYIYGVTMQEKAISKVISLKLKEAQEITDII"
     gene            12332..13612
                     /gene="ftsY"
                     /locus_tag="JAM15_14635"
     CDS             12332..13612
                     /gene="ftsY"
                     /locus_tag="JAM15_14635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HAT6799490.1"
                     /translation="MLKKLFGFGKDKEKEIEKKDAEEEIEVEDSVDSLENLEETIFSG
                     LEEEVIDKVEDIEEKTEESVNNEGTEEIENFEKIEVEMDSNAKEVENISNNDSQEEII
                     EELENYDEIESKEIEDKEDKKVNLFERLKQGLTKAKQGITDRIDEVLKSYTKIDEELL
                     EDLEEILITADVGVNTTMDIIERLRDKIKQKGITEPIKVREELKSIVEDILTNENSTL
                     DIEPAPCIILMVGVNGVGKTTTIGKLANRYKKDGKKVLLAAADTFRAAATEQLEIWAN
                     RTNVDIIKHQEGADPGAVVFDAIKAAKARKTDVLICDTAGRLHNKANLMNELGKVFKI
                     VDREFPEAKREVLLVVDATTGQNAVVQAKTFKEVADITGIVLTKLDGTAKGGVVLAVK
                     SEVDVPVKLIGVGESVEDLQDFNAKSFSDALFGN"
     gene            13715..14083
                     /locus_tag="JAM15_14640"
     CDS             13715..14083
                     /locus_tag="JAM15_14640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HAT6799491.1"
                     /translation="MNIEKMVEIGLLFEQYKELLTDKQKEIVALYYEEDYSLGEISEN
                     LNVSRQGVYDTLKRSEKILRDYEEKLHLVSKIQEQEKNIKIIKDKIIDIKEDLLHNRD
                     CANLIPKLENIEDVCREMIK"
     gene            14080..15432
                     /gene="ffh"
                     /locus_tag="JAM15_14645"
     CDS             14080..15432
                     /gene="ffh"
                     /locus_tag="JAM15_14645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HAT6799492.1"
                     /translation="MIFEGLSDKLQGAFSKLKSKGKLTEVDVKNAMREVKLALLEADV
                     NFKVVKDFIKKVQERCVGQEVMQSLTPAQHVIKIVNEELTSLMGDVQSKVMISSKPPT
                     ILMMVGLQGAGKTTTAGKLGGYFKKQGKKPLLVACDIYRPAAIKQLQVVGEKLDIPVF
                     NMGDKENPVNIAKAGLSHAIKNANDLVIIDTAGRLHIDEVLMDELKSIKSEVKPHEIL
                     LVVDSMTGQDAVNVAESFNEALGVDGVVLTKLDGDTRGGAALSIRAVTQKPIKFMGMG
                     EKLDDIEPFHPDRMASRILGMGDVLSLIEKAQENIDLEKAKELEQKIKKQELDFEDFL
                     QQMEQIQNMGPLDKILGMIPGMGNVKDQLGDVDLNGKEMKRTKAIIQSMTTYERRNPG
                     VLNASRKKRIAKGSGTSVQDVNRLIKQLNEMKKMMKMFAGSQKSMKKRGGLGGLPFFK
                     "
     gene            15470..15742
                     /gene="rpsP"
                     /locus_tag="JAM15_14650"
     CDS             15470..15742
                     /gene="rpsP"
                     /locus_tag="JAM15_14650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HAT6799493.1"
                     /translation="MAVKIRLKRMGANKKPFYRIVVADSRAPRDGKFIEEIGYYNPIS
                     EPKQVRINDEKAIKWLATGAQPTEVVKKLLVKNGVIEKFEASKQAK"
     gene            15807..16034
                     /locus_tag="JAM15_14655"
     CDS             15807..16034
                     /locus_tag="JAM15_14655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016290937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HAT6799494.1"
                     /translation="MKELVVDIAKALVDNPDSVVVEEFEDNDGIVLKLTVAQEDMGKV
                     IGKQGRIAKAIRTVVRSVANRENIKVSLEIV"
     gene            16142..16657
                     /gene="rimM"
                     /locus_tag="JAM15_14660"
     CDS             16142..16657
                     /gene="rimM"
                     /locus_tag="JAM15_14660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA processing protein RimM"
                     /protein_id="HAT6799495.1"
                     /translation="MKEKLTHFKVGQIVNTQGLKGEVRVYPLTDDIERFDELKDFYLG
                     KDLNNKLAVEKVRYKGSMVIMKIKDIDSIEKAEKLKNKFMYVSREDSRELEEGEFFIA
                     DMIGMEVLTVDGKYVGILEDVLQYSANDVYVVKGEEDKEFMIPAIKKFVPTIDIDERK
                     MIIDPIKGMID"
     gene            16666..17361
                     /gene="trmD"
                     /locus_tag="JAM15_14665"
     CDS             16666..17361
                     /gene="trmD"
                     /locus_tag="JAM15_14665"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HAT6799496.1"
                     /translation="MRFHIMTLFPEIFNSYMDESIMKRAVEKGIIEVHIYNIRDFSNN
                     KHKKVDDYPFGGGAGMVMTPQPIYDTYKYIITTHNINNPSVIYLTPKGKVYNQSMAKQ
                     MSLKEDIILLCGHYEGIDERIIDLIVTDEISIGDYVLTGGELPALIMIDSISRLIPGV
                     LNQEESFEEESFKDNLLEYPHYTRPRDFEGLKVPEVLLSGNHKKIDEWRREESIRITK
                     ERRFDLYKKSNEK"
     gene            17546..17896
                     /gene="rplS"
                     /locus_tag="JAM15_14670"
     CDS             17546..17896
                     /gene="rplS"
                     /locus_tag="JAM15_14670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HAT6799497.1"
                     /translation="MNEMLRAIEQEQLKNEVPNFGPGDTVKVHVRIIEGKRERIQVFE
                     GVVLKRQGGGARETFTVRKMSFNVGVERTFPVHSPKIEKIEVTRKGKVRRAKLNYLRG
                     RVGKAAKIKEARNK"
     gene            18244..19113
                     /gene="ylqF"
                     /locus_tag="JAM15_14675"
     CDS             18244..19113
                     /gene="ylqF"
                     /locus_tag="JAM15_14675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006310803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HAT6799498.1"
                     /translation="MNDNLHINWYPGHMKKTKELVKNNLKLIDVVIELLDARIPFSSK
                     NPDIDRLVGDKPRVVVLNKSDMADRDKLNQWIEYYKKINIKAIPVDTIKGVGINKIIE
                     ECKNVTREKMSSLKDKGRKERAIRIMIVGVPNVGKSSLINKLTGRKSTQTGDKPGVTK
                     GKQWVRLKGNLELLDTPGILWPKFEDQEVALNLAFSRAIKDEILDTETLALRLIEKLM
                     KIEPEKLKARYKLDCLGETPIETMDMIGHKRGFITGKKELDYTRIATTVLNEFRDGKI
                     GNITLEVPENVKR"
BASE COUNT         8262 a         1754 c         3465 g         5860 t
ORIGIN      
        1 aagtatatga aataaatatc ctgtatttaa gcttatagat tataatgaaa tataatacat
       61 attataataa caaaacgaac taaaattatc acactaaagc ataaaacata ttctaatcat
      121 gttagataaa tttttgaata tataatccaa aagtactttc taaagtagag tacttctttt
      181 ttattaatta tttttatata gaataaattg gaatttatat ttattccaat ctaattgatt
      241 acatacactt attgttataa agtttagtta tacataaatt ggtaagaggt gtaaactaat
      301 gaagattaat aaattaccac atgcggaact aaaactaatg aagtatattt ggggagtaga
      361 tgatgtatta gcctcaagag atatcataga aacaatgaag ttgaaatacg attggaaaaa
      421 gagcacaaca ttgacatttt taaaaaattt agtagataag ggctttttaa ctactgataa
      481 ggtagataga tgtacgcatt atactatagc tataaaagag aaagattatt taaaagttga
      541 gacaaagagt ttctttagtt ttatgcataa caattcattt aagagtttta tttcagcatt
      601 acatgatgat gaagttttag atagtaaaag cttggacaaa ttagaagaat actttaaaaa
      661 tttgaaagaa gaagatattg atgactaata aagctatcag tatcttttta gtttgagaca
      721 attgagagta gcgttttgat ttaatgttag tgttatgtga tggtagaaaa ttatataaag
      781 aaaagtgatt atttccttag tatttgatag taaaaaatat agaaaataat accaactaaa
      841 ttttaaagaa agatatgaaa tactacaata gcttaaatca tgcaaatatg ataaagaaat
      901 tgaaattata aaaggaatat aattttagaa gaaatagttg acagataaat taccttacta
      961 tattattgta ttaataaaat aatacaataa tatagtaagg aggtaataaa tgaaatctag
     1021 aaaacataat attacaaaag gattatttat agtttacata attgttttaa catggataat
     1081 actattcaag ttgcaatttg atatttcatc ccttgaaacc atgaatctta gaagcataaa
     1141 cttagtacct tttgctgggt cacttataat taataataga gtagatatat cagagattat
     1201 attaaatgtg gttatatttg taccatttgg gatatatgtg tgtatgctaa aagaaaaatg
     1261 gagctttata aaaaaagtta tacctatttt tataactagt ttagcatttg aaacacttca
     1321 atatatattt gcactaggtg caagtgatat aacggatttg ataggaaata cactaggagg
     1381 aatcatagga atagctgttt ttatgctatt atcgaaaata tttaagaata atgccataaa
     1441 aattatcaat gtattggcat tgattgtgac aattattgtt gtattatttt taggattagt
     1501 tatttttgca aacttataga aataagtata tatgtttagc ttaaaataaa atgtaagata
     1561 caattacata taaaattatt tacacataaa aagcacctat acaggtgctt tcctaaatta
     1621 ttaaagaatt attgtatctt gaaactcttg tatgttcaat tcttgatttt ctcttgtttt
     1681 ttctaataaa tctaacgcac aatttataca aactttaatt tctgcattgg tatttttctc
     1741 ataataagtt atatatttat ttctatattt atctatttct tttccacaac gactacacat
     1801 tacaattacg ctcatatctt agttcctcca tctctaatta ttcttaatat attcaatagt
     1861 atcacttttc tgaaaataat gattgttaaa actgtatcaa atttagattt actttttatt
     1921 ataatgcatt ttaataaaaa aataaaggtt atgagtaaaa tatttataga aaaaagtata
     1981 ttattgaata gattataaaa ttttattatt ttttatcagt cttaaataca cattaatatc
     2041 tataaaatga caaaataaaa aatactattt aaatagatat taaaaaagtg ataccaagta
     2101 tttgtttgct atatgaataa caatttattt aggagcttta ctttgacact gtataataat
     2161 aaagtaattg ctaaaaacgt tggatgattt ggatgtattt ttagaaatta gaaaaatata
     2221 tacttactga ctaatgataa tcttatatgt attttagttt gagtgattta agaaaagtgt
     2281 tttgaaaagg gattatttta tagagtaaat aaatatatat atatggtaga aaaattacat
     2341 ataaaaagta gcgtttattt cattaccttc tttatctgtt ccgatggggt cttgtagaga
     2401 tacttgagtt ttattttttt tgttagatct aatattcatt aaaatctcat tttcaataca
     2461 tctagaagca tatgttgcta atcgagttcc tttatctatg ttataagttt ctatagcttt
     2521 aattaatcct attgtaccta tggatattaa atcatcctga tcttccgttg aattattata
     2581 tttctttgct atataagcta ctaatctcat gtttctttca attaatgtat cttttgcact
     2641 tttatcgttt tctattttaa atttagttaa atactcaatc tcttcttcag gggttaaggg
     2701 tttttcaaaa gatttaagag ctgccaatag gtcaccccct tttcaacggt cactttaaat
     2761 tatatgaagg agacttatcc aagttgactg ttatctaata aaataatatg catattttta
     2821 gaatttaaaa catatatttg caaacttttg aatggaatat gacataaaga gtgggaattt
     2881 aaatttaagt ttttgttgta tatatatgaa acaaggcgaa gaaattattg atttataaag
     2941 tataaattgg aattgaggtg tcaataaata taaaaggaaa tagtatttat atatgttttg
     3001 gtgttgaggt aaaagattaa tgcaaagcat tagagtctat aaaaatatga atataggagg
     3061 tgtaatttta caatacttaa aaaagtaaat gtaattaatt gtttgtataa agttgattac
     3121 aagcaaaaag tatcagtcat agttaattct gttaaggatg aaggtggtgt gttaatttat
     3181 atatgtatgg gaagaaattt tgattacaat gaaaaaactt acaaaagata tttatgaaaa
     3241 aacttatagt taaatgttta tatataaaat attatttagg ggttgttttt attattgaaa
     3301 ataagaaaga gtggttttat atcaatcgaa tgtataataa gtattgctat attatatgtg
     3361 gctgtttatt tagtttctac atcattgtat aattgttata gttttatcag tagaaatata
     3421 tctgacagag aaatgttaag tacagcaaaa aaatatatag aagatgagaa gtatagaata
     3481 caaaatagta agtatgagtt aattgaagat aagatagaaa aaaattacat aaatggatat
     3541 gaaattaaca gtagaataga gcaaatttta gattattatc aatgctatga aataaatata
     3601 gagataaaaa atgaatttaa aaaactgagg tttaatagct atgttactag aaaataaagg
     3661 ctctatatta ataataacat tgataatatt ttctattata agtactgtgt gcattatgtg
     3721 tataggttta atttatacac ataataatat gtttgagtta ggatacaagg acattcaact
     3781 aaaagaaatt tctttaagtg gaatagaaat atcagtaagt aatgtacttt cttgtgttga
     3841 ggaagctatt gatgtatcta ataatgaaga cgaatttaga gaatatttct taggaaataa
     3901 tatgattgaa tgtataaaaa aaataaaaga tacatcttat agtagtttag aagaactttc
     3961 tttaaaagta gaaaataata ctatttatga cagaggagat ttttttgaat ttgatataga
     4021 aagtaatgtt agagaaaaag aatttttaaa agcaataaaa gtaagagtga aaatcaaaaa
     4081 tccatggata ggaattgaca ttgaagatta tatggataaa tctaataaca ataaaattga
     4141 tgacaaaaca ttcaataatt ataaagcatc tgaaaataat gaaattctaa atcaatttaa
     4201 aaatgaaagt gaaaatataa ggaatcaaga ggttgttgaa tttacagaag aagatgaaga
     4261 atatgaagaa gaacttaaac aaaacataat tgaaaatata aagaagaatt ttgatgaaaa
     4321 aaaactagta caggtatata agtatagggg tgtataactt tgaaaaaaga aggaatgtga
     4381 ctgtaataga attaatagta tctatcagta taatactctt gatagttaca ttatcttttc
     4441 caaaggataa tcttgaaaat cataaaataa atttatttgc acgtcaactt tgttcagata
     4501 taaggtatgt taggcgaatt aatatgttta gcaactacaa tacatatata tattatataa
     4561 atcaaggtaa atacgaaggt tatgtattga gaaaagatgg taaaaacatt aaatcaataa
     4621 tgctacctaa aaatgcaaaa atagctagaa gtattgaaat aataaagttt aaatctgatg
     4681 ggtcgcctca aaaggcgtct acaatagaaa tatataataa tagattaaga aaaactataa
     4741 caataacacc tgtaagtgga agagtacttc tgaaagaggg aaaatatgaa acataaatat
     4801 ggttacttgc ttttggaaag tgtagtatca ttgtcttcaa tggtgataat tatactagtt
     4861 ttatattcta tatttttgtc tacaataaac ttaaagttaa aagtagaaga taagatagaa
     4921 ctacaacaac aaagtcttga aatcataaaa tctatggaag gaattattag caattctatg
     4981 ggaataatga atgtatctaa ttatgaagaa acatttaaaa agacaacgtc tataaaatgt
     5041 agatatgtag atgaaaataa taatgaagaa agcataagta ataaagaaat tatattgaat
     5101 gaaagacgaa ataagttatt tgtaaattct ttaaatggcg aaagtagtca agcaggtggt
     5161 tatgaaattg gagattatgt agatgagatg tatgtattaa ttactaataa tggtcaatat
     5221 gttaatatta aattgaaatt atcaaaacgt agtcaaaaat atgagactga tttcaaaata
     5281 aaagtatgga attttagtga aagtatataa aaatacataa atttaagata aagaaatgac
     5341 atcaataagt catataaaat ataattattg agaactatat aactaaataa tatcaatatg
     5401 taaagtgtat agattaagaa tatagaggat aataataaaa atatagaata agtaatttgc
     5461 caaatacttg tttatattgt ataacttatg atattatgat attagtaaaa atttgtaatc
     5521 ctgacttgac agaattcaag taagagatat aattttaaag gcatagtaat gtaaaattta
     5581 ctaaaaaata agaaatttat tttaatatgg aggaacaaaa aatggtatca gcaggtgatt
     5641 ttagaaaagg tgttacattt gaaaaagatg gacaaccatg tttagtagtt gattttcaac
     5701 acgttaagcc aggtaaagga gctgctttcg ttagaactaa atacaaaaac ttaaaaacag
     5761 gagctataag agaagaaagt ttcaatccaa gtgaaaaatt ccctaaggct gttatagata
     5821 caagacaaat gcaatatcta tacaatgatg gtgagttata ttattttatg gatcaagaaa
     5881 attttgaaca aataccatta aactatgagc aagttgaaga tgcaattaag ttcttaaaag
     5941 aaaatgaagt tgctacaata agattttacc aaggacaacc attccaagtg gaagcgccaa
     6001 actttgcaga gctagaagtt acagatacag agccaggtat aaaaggtgat acagcaagta
     6061 atgtaactaa agcagctaca gttgaaactg gagcagttgt tcaagttcca ttatttataa
     6121 atactggaga taaagtaaag atagatacta gaacaggtga atatttatca agagtataaa
     6181 aatttatgta tataaaagct tatatgtctt aataatataa gatatatgag cttttagttt
     6241 atatataaaa aagaaagcga ggggtgttac atgaaacatt tatatgaaga agttgcatac
     6301 ttaaaaggcc tagcagaagg actagaaata agtgctgaaa gtaaagaagg gaaaatgata
     6361 cataaaatag ttgatgcatt agaagtattt gcagatgcta ttgtaacatt ggatgaagaa
     6421 caagaagaac ttcaagattt tgttgaatct atagatgaag atttagcaga tttagaagaa
     6481 gatattgctg acatggaaga agatctttat gaagaagatg acgatgagga tgatgaggac
     6541 ttcagctata tagaaatgga atgcccaaat tgtggagagt tagtagaaat agacgaagat
     6601 ttgttatatg atgatgaagt agatgttgtt tgtcctgatt gtaaggctgt gatattatca
     6661 tcagaagatg attgtgatga tgattgtaca tgtggtggtt gttcaagttg tgatgataga
     6721 gagtaaaaat tcataagaat taaaactgcc tatgatgcct atgagatatt ttgcttcata
     6781 ggtagtttta tttttatgag gaagggtatt atgtattttg gttttgcaat acttggacaa
     6841 aaatagtaca ctagaattta tagaatagga ttttggaggg atgtaaatat gaaaataagt
     6901 aaaaaattac tagataatat acaaagattt gaaaatgtta taaattataa atttaaaaat
     6961 aaagaatata tactagaagc tcttactcat agttcatatt ctaatgaaaa taaaaaatat
     7021 aattttaacg aaaggttgga atttttaggg gattcggttt taggcatagt gataagtgat
     7081 tatttattta atgaagaagc taatctgccc gaaggggaac taactaaact tagagcaaat
     7141 atagtttgtg aagattcgtt aagtgaagta gctaatgata taaatttagg tattcacatg
     7201 ttattaggta gaggagaaga agcaacagga ggaagacata ggacttcaat attagcagac
     7261 gcatttgaag ctgtaatagc tgctatatat cttgatggag gttttgaaag tgcaagacag
     7321 tttatacttc atcatatgga aaatataatt tatgattcaa gaaaaggaaa tatatttaga
     7381 gactacaaaa cgcatcttca agaagtgtta caagggaatg gagaaaataa tatctggtac
     7441 aggcttatag aagaaaaagg accagaccat aataaaagat ttgtaatgga agttggaatt
     7501 aatgacgatg tattgggtat aggagaagga aagagtaaaa aagaagctga acagttagct
     7561 gctaaaatag ctttaaagaa aaaattatgg gaaaaataaa tataatatgt aaaaatataa
     7621 aaagaaatat ttatattaga aggatgttgt agatgaaaaa gagaattata cctatatttg
     7681 ttcctcacaa aggatgtcct catgattgca tattttgtaa tcaaaaaaaa ataacaggtg
     7741 tgagtactga tgttactagt gaagatgcaa gaaatataat tgaggaatgt ttagagacta
     7801 tagataaaga tgcagatgta gaaatagcat tttttggtgg tagctttact gctatagata
     7861 ttgatataca aaaaagttta ttatcagttg ctaaagaata tgtagaaaaa ggtcttgtaa
     7921 aagatattag aatgtctaca agaccagatt gtattgatga agatatatta agtatgctaa
     7981 aagaatataa gacaagtgta attgaactag gagtacaatc cttagatgaa aaagtattat
     8041 tagatagtat aagaggtcat caatctgaaa ttgtatacaa gagttcaaag atgataaaaa
     8101 atagtggaat caaacttgga ttacagatga tgattggtct tccagctgac acagaagaaa
     8161 agtgtatatt tacagcaaaa aaatttgtag agctaaaacc agattgtgtt agagtctatc
     8221 caactttggt agtaaaagat acaggtcttg aaaagttaat ggaacaaaat aaatataatc
     8281 catttactct tgaagagagt gtaaatatag taaaaaaagt tcttgtactg ttttatgtta
     8341 ataatatcaa tgtaataaga gttgggcttc aagctactga tgatatacaa attggaaaag
     8401 ctgttttagc aggaccatat catcctgcat ttagagagtt ggtagaagca gatatgataa
     8461 aagattattt agaatttgtt attttgcaaa ataaaaatat aaagcaaatg ttggtcaaat
     8521 ctaataaaaa gaatatttct aaaatcatag gaaataaaaa aacaaatgtt aaatatatgg
     8581 aagaaaaatt tggtgtgctt ttaaaaacac aagaatccga tttagatata aatcaattag
     8641 aaattgtgtt agatgggaaa agtttaatta gtgctaatat gagagacatt catagaaaat
     8701 tgtatgacat ttatgacctt tagttttaat aatgaaggga gagaaaagat ttgtatttaa
     8761 aaagactaga gttaaaggga tttaaatcct ttccagtaaa aacagatatt atttttaaag
     8821 aaggaataac agccatagta ggaccaaatg ggagtggaaa aagtaatata tctgatgctg
     8881 taagatgggt attaggagaa cagagtatta agagtcttag aggtgataaa ctcgaagatg
     8941 taatatttgc aggtacagat acaaaaaaac ctatgaatta ttgtgaagtg gctcttacta
     9001 ttgataattc tgaaaatcaa ttggaattag attttacaga agtaactata agaagaaggg
     9061 cttatagaaa tggtgaaagt gaattttttc taaataataa aagttgtaga ttaaaagata
     9121 taaaagaagt ctttttagat actggtattg gaaaagatgg ttattcaatc atagaacaag
     9181 gaaaagtaga tgaaatatta agtaataatc ctttaagcag aagaaaagtt tttgatgaag
     9241 cttgtggcat atcaaaatat agatataaaa aacaggaagc agaaaggaat ttaagtaata
     9301 caaaggaaaa tttagaaaga atagatgatg tatatataga aattgaaaat caattaaagc
     9361 ctctttttaa tcaacagaca aaggcaaaaa agtacttgga aataagtgaa aaattaaaga
     9421 tacttgaagt aaatagcttt ataagagaaa ttgaaggaat agaaaaagaa ttaagtgagg
     9481 ttaatgaaca tcgtaaggtt attgaaaagg agctcaatga aaaagaagaa caaaaaaatg
     9541 ttgtagagaa aaagcaagaa gatattaata aagaggtaga ggtattacaa gatgtaattg
     9601 aaaaatctgt agattatata aattcaatta aaggagttat atcaaaaaaa gagtcccaaa
     9661 taaatttaat taaggaaaga ataagaaatt ttacgaatga aattagtaga aaaaatttag
     9721 aaataaatga tataaaagag aagctaaatg aaaataagca atacataaaa gaattagaaa
     9781 gtaataaatt atcaggtagt gaagaactat ctaccttgca ggaaaatata aaagtattgg
     9841 aggcaagtaa agataaacaa aaaattaagt tagaatccct aaataatgag atagaattat
     9901 tgaaagaaag tataattgat atattaaata agaaacaaga gtttagtaat aagctgtcca
     9961 ctttaaacgc aaataaagaa aatatgaata tcagagatga aaatataaat tcagagataa
    10021 cagagttaaa caaaaatatt gaaataaaat catctgaatt agatactata aataaagaat
    10081 ttaatatgca aaatgaaaat ttaaagaatg taaataatag acataaagaa ttatcaatta
    10141 atttgcagga ttcaattagt gaacacaata aactagaaga tgaaatacag aaaagtaaat
    10201 ataatttaaa tggatataat tcaaagttaa atgtctatat agatatggaa aatcattatg
    10261 aaggatttaa tagaggagta aaagaagtac taaaaaataa aaatttaaaa ggagttcatg
    10321 gagcattagg acagattata aatgtacctg aaaaatatga gaaatctata gaagcagctc
    10381 ttggtgctta tatgcaaaat ataataactg ataatgagtt tagtgctaag tctgcaataa
    10441 actatctaaa acagaataat ttaggtagag taacatttct tccattaaat ataattaaat
    10501 caaataaagt aagtctagga aatttaaaag caaatactaa gttcatagga atagcaagtg
    10561 atttaattac atttgatgaa aagtatagaa atataattga aaatatactt ggaagaacaa
    10621 tacttataaa taatatagat gagggcataa aatttgcaaa agaaactggt cataggttta
    10681 aaatagtaac tttagatggt gaaatcttaa atccaggagg ttctttgact gggggaagtc
    10741 taaaaactaa tggtaatata ctatcgagaa aaagatacat taatgaatat acagaaaaga
    10801 taagtaatat caagaatgaa atttcacatc tagaattaaa aagagaatct ttagacaaag
    10861 atgtgaaaaa tatcaaaaat gaaattgatt cacatgaaag taaaataaaa gatttagaaa
    10921 aaagtataat aataaaaagt acaagtataa agaatgttga atctgaaatt gaatcgttaa
    10981 aaggtagtat tactaaatta gaaaatgaga agaatgattt aaattctaat ctaaattata
    11041 cacttgaaaa aagcgatgat gttagaaaag atatggaaga gttagatgat ttatacaata
    11101 aaaataaaga aaaaattgat gcattgaatg aggaaataaa aagatacaat gatttatatg
    11161 ataaagaaaa atctgaattt gatgaattga acttaagttt agtgaagaaa acagaagctt
    11221 acaatagtat agttagagat ataaaaagaa tatctggtga aaattgtgag ctagaagaaa
    11281 agaataaaca attagaagag tcattaaatt atgaagaaca tgaaataatt aaattacaag
    11341 attctatagc cactgaagaa aaagaaaaag aaaatttaac aaaacaacta ggggatagta
    11401 atagaaatct tgaaactaga aaaatagcaa aagatgattt aaaaaatagt tttgatgaaa
    11461 ttaataaaga attaaaaact atagatagac agcatataga gcttaaagaa agtttattta
    11521 aagttggtgg aagattagaa agattaaaaa ctagtcaaga cacatatata aataagttgt
    11581 ttgagcaata tgatatgact ttagtacaag cattggaaat taaagatgaa gatttggata
    11641 tagatagaaa attcttagaa agtctaaaga gagaaataag aagtcttgga aatataaata
    11701 tagactctat aaaggaatat gaggaaataa aagaaagata cgatttttat agcgaacaaa
    11761 agcaagattt agaagagtct atggaagaga tagaaaaact tatacacact ttagaagaaa
    11821 atatgaaatc tgaatttgaa attaagtttg aagaaataag taaaaatttt aaatatgtat
    11881 ataagagatt atttggtgga ggttgtggag aattaactat tttagataaa gaaaatttat
    11941 tagaaagtga tatactaata acagctcaac ctccagggaa aaaaatgaaa aatttaaatc
    12001 tattatctgg tggagagaaa gctttaacag caataagtat attatttgct atattgatta
    12061 caaagccaac accattttgt atattagatg agattgaagc gccacttgat gatgcaaata
    12121 tatttagatt tggagaattt ttgaaggatt tatctaaaga gactcaattt atatcagtaa
    12181 ctcataggag aggaactatg gaagctgctg attatatcta tggagttaca atgcaagaaa
    12241 aagccatttc aaaagttatt agcttaaaat taaaagaagc tcaggaaata acagatatta
    12301 tataacttag attgacatag gaggaataac agtgttaaaa aaattatttg gttttggaaa
    12361 agacaaggaa aaagaaatag aaaaaaaaga tgctgaagaa gaaatagaag ttgaagacag
    12421 tgttgatagt ttagaaaact tggaagaaac cattttttca ggacttgaag aagaagtgat
    12481 agataaagtg gaagatattg aagaaaaaac tgaggaaagt gtcaataatg aaggtactga
    12541 agaaatcgaa aactttgaaa aaatagaagt tgagatggat agtaatgcaa aagaagtaga
    12601 aaatatttca aataatgatt ctcaagaaga gataatcgaa gaattagaaa attatgatga
    12661 aattgagtct aaagagatag aagataaaga agataagaaa gttaacttgt ttgaaagact
    12721 aaaacaagga ttgacaaaag caaagcaagg aataactgat agaatagatg aagttttaaa
    12781 atcatataca aaaatagatg aagaattact tgaagattta gaggaaattt taataacagc
    12841 agatgttggt gtaaatacaa ctatggatat aattgaaaga ctaagagata aaataaagca
    12901 aaaaggtatt actgaaccaa taaaggtaag agaagaactt aaatctatag ttgaagatat
    12961 tcttacaaat gaaaactcta cactagatat agaaccagca ccatgtataa tattaatggt
    13021 gggtgtaaat ggggtcggta agactactac aataggtaaa ctagcaaata gatacaaaaa
    13081 agatggtaaa aaagttttat tagcagcagc agatacattt agagcagcag caacagagca
    13141 attagaaatt tgggcaaata gaaccaatgt agacataata aaacatcaag agggagcaga
    13201 ccctggagct gtagtatttg atgctataaa agctgcaaaa gctagaaaaa cagatgtatt
    13261 aatatgtgat acagcaggaa gattacacaa taaggctaat cttatgaatg aacttggaaa
    13321 agtatttaaa atagtagata gagaatttcc agaagcaaaa cgtgaagtac ttcttgtggt
    13381 ggatgctaca acaggtcaaa atgcagttgt tcaagcaaag acatttaaag aagttgcaga
    13441 tataacaggt atagtactta caaaacttga tggaactgca aaaggtggag tagtccttgc
    13501 agtaaaatca gaagtagatg tacctgtaaa acttattgga gttggagaaa gtgtagaaga
    13561 cctacaagat ttcaatgcaa aatcattttc agatgcatta tttggtaact aatgttcttt
    13621 taaaaataat ggttgacaag agtgttgtta tgatataaaa tacaatagtg taaagtaaat
    13681 aacctttaca gtatactgct aggaagtgta agatatgaat atagaaaaaa tggtcgaaat
    13741 tggattgtta tttgaacagt ataaagaatt attaactgac aagcagaaag aaatagttgc
    13801 tctatactat gaagaagatt attctttagg tgaaattagt gaaaatctga atgtatcaag
    13861 acaaggtgtt tatgatacct taaagcgttc agaaaaaata ctaagagatt atgaagaaaa
    13921 gttacactta gtatcaaaga ttcaagagca ggaaaaaaat attaagatta taaaagataa
    13981 aattattgac attaaagaag atttattgca caatagagat tgtgctaatt taatccctaa
    14041 gctagaaaat atagaagatg tatgtaggga gatgataaaa tgatatttga aggattgtct
    14101 gataaactac aaggggcatt tagtaagtta aaatctaaag gaaaacttac agaagtagat
    14161 gtaaaaaatg ctatgagaga agttaaactt gctcttcttg aggcagatgt taactttaaa
    14221 gtagttaaag atttcataaa aaaagttcaa gagagatgtg ttggacaaga agttatgcaa
    14281 agcttaactc cagctcagca tgtaatcaaa attgtaaatg aagagcttac aagtttaatg
    14341 ggagatgtac aaagtaaagt aatgatttcc tcaaagcctc ctacaatttt aatgatggtt
    14401 ggattgcaag gtgcaggtaa gactactaca gcaggaaaac ttggaggata ttttaaaaag
    14461 caaggtaaaa aacctctatt agtagcttgt gatatttata gaccggcagc tataaagcaa
    14521 cttcaagttg ttggagaaaa attggatata cctgtattca atatgggaga taaagaaaat
    14581 ccagtaaata ttgcgaaagc aggtttaagc catgcgatta aaaatgctaa tgatttagtt
    14641 attatagata cagctggtag acttcatata gatgaagtac ttatggatga gttaaagtct
    14701 attaaatcag aagttaagcc acatgagata cttttggttg tagattctat gacaggtcaa
    14761 gatgctgtaa atgttgcaga aagcttcaat gaggcacttg gtgttgatgg agtagtatta
    14821 actaaattgg atggagatac tagaggtggt gctgcacttt caataagagc agttacacaa
    14881 aagcctataa aatttatggg gatgggagaa aagctagatg atatagaacc tttccaccca
    14941 gatagaatgg catcaagaat attaggtatg ggagatgtct taagtttaat agaaaaagca
    15001 caagaaaata tagacttaga gaaagctaaa gaattagagc aaaaaattaa aaaacaagag
    15061 cttgattttg aagatttctt acaacaaatg gaacaaatac aaaatatggg acctcttgac
    15121 aagatacttg gtatgatacc tggtatggga aatgtaaaag accaacttgg agatgtagat
    15181 ttgaatggca aagaaatgaa gagaacaaaa gccataattc agtcaatgac tacatatgag
    15241 agaagaaacc caggagtatt aaatgcttca agaaagaaaa gaatagctaa aggcagtgga
    15301 actagtgtac aagatgtaaa tagacttata aaacaactta atgaaatgaa aaaaatgatg
    15361 aagatgtttg ctggttcaca aaagagtatg aagaaaaggg gcggcttagg cggtttacct
    15421 ttttttaaat aaaatataaa aaagtaaaaa ttattcggag gtgactgtaa tggcagttaa
    15481 aataagatta aaaagaatgg gagctaacaa aaaacctttc tacagaatag tagtagctga
    15541 ttcaagagct ccaagagatg gaaaatttat agaagaaata ggatactata atccaatttc
    15601 tgaacctaaa caagtaagaa taaatgatga aaaagctata aaatggttag ctactggtgc
    15661 tcagccaaca gaagtagtta aaaaattact tgtaaaaaac ggagtaatag aaaaattcga
    15721 agcttctaaa caagcaaaat aattttttct tggcaattag tttaagtaag ggctcattgc
    15781 taaggttact ttaggagatg aaatatatga aagagctagt tgtagatata gctaaggctc
    15841 tagttgataa tcctgactca gttgttgttg aggaatttga agataatgat ggtatcgtct
    15901 taaagcttac agttgctcaa gaggatatgg gtaaggttat tgggaagcag ggaagaatag
    15961 ctaaagctat aagaactgtc gtaagatctg ttgcaaatag agaaaatata aaagtttctc
    16021 ttgagatagt ataaaatagg aggattaggt ataatgccta gtccttttta tataaatgcg
    16081 tagtttaaga ttttatgatg atatgaccac ataagattaa attttttaag aaggtgataa
    16141 catgaaagaa aaattaactc attttaaggt aggtcaaata gtaaatacac aaggtttaaa
    16201 aggtgaagta agagtttatc cgcttactga tgatatagag aggtttgatg aattaaaaga
    16261 tttctatctg ggaaaagatt taaataataa attggctgtt gaaaaagtaa gatacaaagg
    16321 ttctatggtt ataatgaaga taaaagacat agacagcata gagaaagcag agaaactaaa
    16381 aaataagttt atgtatgtat ctagggaaga tagcagagaa cttgaagaag gtgaattttt
    16441 tatagcagat atgattggaa tggaagtttt aactgtagat ggaaaatatg taggaatact
    16501 agaagatgtt cttcaatact cagcaaatga tgtttatgta gtaaaaggtg aggaagataa
    16561 agaatttatg ataccagcta taaaaaaatt tgtacctaca atagatattg atgaaagaaa
    16621 aatgattata gaccctatta agggaatgat agattaggtg gtaatatgag atttcatata
    16681 atgacacttt ttccagaaat atttaattcg tacatggatg aaagtataat gaagagagca
    16741 gttgaaaaag gtataattga ggttcatata tataatataa gggatttttc taataataaa
    16801 cataaaaaag tagatgatta tccatttgga ggaggagcgg ggatggtaat gactcctcaa
    16861 cctatatatg acacatataa gtatataata acaactcata atataaataa cccaagtgta
    16921 atttatctta ctccaaaagg taaggtatac aatcaatcta tggcaaagca gatgtcttta
    16981 aaagaagata taatactact atgtggtcat tatgaaggaa tagatgagag aatcattgat
    17041 ttaatagtta ctgatgaaat ttcaattgga gattatgtat taactggggg agagctccca
    17101 gcacttataa tgatagattc tatatcgaga ttaataccag gtgtattaaa ccaagaagaa
    17161 tcatttgaag aagaatcatt taaagataac ttattggaat atcctcatta cactagacct
    17221 agagattttg aaggattaaa agtaccagaa gtgcttttat cagggaatca taagaagata
    17281 gatgagtgga gaagagaaga atctataagg ataaccaaag aaagacgatt tgatttatat
    17341 aaaaagtcta atgaaaaata aaaatataat gaaaaattaa tatatatgta tacaataaag
    17401 tacctataaa tggaattaaa aacataaaag tgcttgtaat aactattgaa gtatagtata
    17461 atataaaatg ttgaaaatac gggcgttcct ctgtttacac tggtcgggta gttaagaacg
    17521 tctatgatat ctaggaggaa gaaagatgaa tgaaatgcta agagcaattg agcaagaaca
    17581 attaaaaaat gaagttccta attttggacc tggggacaca gttaaagtac acgttagaat
    17641 tatagaagga aaaagagaaa gaatacaagt attcgaaggt gtagtattaa agagacaagg
    17701 tggaggagca agagaaactt tcacagttag aaaaatgtct ttcaatgttg gtgtagaaag
    17761 aactttccca gttcactctc caaaaataga aaaaatagaa gttactagaa aaggtaaagt
    17821 aagaagagct aaactaaact acttaagagg tagagtaggt aaagctgcta agataaaaga
    17881 agctagaaat aaataattaa aaactttact tataaatggg gggctgattt atcagtcctc
    17941 tttctatttt aatgaaaatt acagcaaata attatactag aaataaatag aaatatttgt
    18001 tgaaaatata cattatttat ctatgaattt atagctttta aaatgaaaaa taaaattggt
    18061 aaatattgga ttatgttttg taacgatatt aaaaataaga gaacagtatt atgtaaagta
    18121 tgacgttaaa aagatgacaa tattatagtt tgttaagata gattttttaa gtggaattag
    18181 gatataataa tataatatta ataaggagtg atacatgtgt caaatgaata cgaagagtat
    18241 cttatgaatg acaatctaca tataaactgg tatccaggtc atatgaaaaa aactaaggag
    18301 ttagtaaaaa ataacttaaa attgattgat gtagtaattg aacttttgga tgctagaatc
    18361 ccgtttagta gtaaaaatcc agacatagac aggcttgtag gagataagcc aagagttgtc
    18421 gtacttaata agagtgatat ggcagatagg gataaattga atcaatggat tgaatactat
    18481 aagaaaatta atatcaaagc tataccagta gatacaataa aaggcgttgg tataaataag
    18541 ataatcgaag aatgtaaaaa tgtaactaga gaaaaaatga gttctttaaa agacaaaggg
    18601 agaaaagaaa gagctatacg aataatgata gttggagttc caaacgttgg taaatcgtct
    18661 cttataaaca aattaacagg tagaaaaagc actcaaactg gagataagcc aggagtaacg
    18721 aaagggaaac aatgggttag attaaaggga aatcttgaac ttttagatac acctggaata
    18781 ctttggccta agtttgaaga ccaagaagtt gcattaaatt tagcatttag tagagctata
    18841 aaggatgaga ttttagatac tgagactttg gctttaagac ttatagaaaa acttatgaaa
    18901 atagaacctg agaagttgaa agccagatat aagttagatt gtctaggaga aactccaatt
    18961 gaaactatgg atatgattgg ccataaaaga gggtttataa caggtaaaaa agaactagat
    19021 tatacacgca tagccacaac tgtattaaat gaatttagag atggaaaaat aggaaatata
    19081 acattggaag ttccagaaaa tgttaaaaga tagattttaa aacaaaatca aaaatttaat
    19141 gttaaaaatt taaaaaagcc ttttagcaaa ggctttttta tttttttgaa atatagacaa
    19201 atatctccat ataaaagtat aaattaggtt agaaaacctt taaaaatatt aatttaagac
    19261 aaatatacct aatattttga aaattaaaat gaatgtgatt atttaaaatt ttagcatatt
    19321 gacttgcttg tttcgtataa t
//
LOCUS       DACTZW010000079        19191 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.079, whole genome shotgun sequence.
ACCESSION   DACTZW010000079 DACTZW010000000
VERSION     DACTZW010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19191)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19191)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19191
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.079"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(313..1209)
                     /locus_tag="JAM15_14680"
     CDS             complement(313..1209)
                     /locus_tag="JAM15_14680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAT6799499.1"
                     /translation="MKDKNTYFNRKGQENFIDIFLKDDIKKGANFKRHWHEHLQIYYF
                     IDGIAYLECGLDNFKVVPGNIVIANSNELHYLESLSDNLKFYSIRIEPTFLFSNQVDL
                     LQTKYLAPLALNHIVFNNLIQNDFLILKCITTILDEYHNKEVGYELSIKANIYQLIVL
                     LLRSHIDKIYSEDEFIKRKYSLEKFECIFDLIEEKYMDKITLKELASRVNLSAHHFCR
                     TFKQITGKTTIDFINGIRLDKAIYYLKETDLNMTEIAMRCGFDSINYFSRLFKRNYNI
                     SPTKYRNEHREVSNVILKEDMK"
     gene            1351..2778
                     /locus_tag="JAM15_14685"
     CDS             1351..2778
                     /locus_tag="JAM15_14685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAT6799500.1"
                     /translation="MTNSFKKDDNRKKITVLFVVIAMTFMATLDSSIINVALPVLASK
                     LNVSLASIEWVIASYSIIICSTLLFFGRLGDIIGKSRVFQVGTILFTSASLLCGLSNS
                     LTLLIVCRFIQGIGASAYMANNHGIITELFPKESRGKALGILVTAVAIGNMVGPSVGG
                     FILSIFDWNVIFFINIPIGLIVIFLNTKFLPNSKKSSENMDKTGAILQFLGTTLFFSA
                     LISAQQTGLLNPYILIALLLSIIFIILFLILEKKHPQPLLDLEIFRNFKFSLNLICAL
                     TSFICIASSSILIPFYLQSTMKLPPIQAGLFMILSPLILAIFSPIFGNISDKIKSEKI
                     ILIGLLVMSFGFFLMSRLKESSALILFVIYISIISIGQAIFQPANNALIMSSCSRSKL
                     GVVGSINSLVRNLGQVIGITISTTLLYNFMSIKAGYRVNDYVINNDKIFVFGMRNVYI
                     IVTLVCLIGAILIGFYLFKYNKNEQ"
     gene            complement(2975..5569)
                     /gene="clpB"
                     /locus_tag="JAM15_14690"
     CDS             complement(2975..5569)
                     /gene="clpB"
                     /locus_tag="JAM15_14690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HAT6799501.1"
                     /translation="MDVEKMTLRVQKSLNEAYNEAVKNHNQQVDVIHLFSALINQEDG
                     LIPNIIEKMNIPIDSLRNTVNFEIDKLPKVYGEGADSQGVSATRKINEVLIKAESISK
                     EFKDSYISVEHVMLAMMETESKSAVGKILKQYNINKNDFLNILSQVRGSQRVETQDPE
                     GTYDALARYGTNLVDLAKKNKLDPVIGRDEEIRRIIRILSRRTKNNPVLIGEPGVGKT
                     AIVEGLAERIVRGDVPEGLKDKIVFSLDMGALIAGAKYRGEFEERLKAVLKEVQSSDG
                     KIILFIDEIHTIVGAGKTEGSMDAGNLIKPMLARGELNCIGATTFDEYRKYIEKDKAL
                     ERRFQPVIAEEPTVEDTISILRGLKERFEIHHGVRIHDNAIVAAAKLSHRYIQDRFLP
                     DKAIDLIDEAGAMIRSEIDSLPTELDVVRRKLFTLETEREALLKENDDKSKSRLDDIQ
                     KEIAELKSKNDEMTAKYEKEKSQILDIKNLKAQLDEAKGKAEKYEREYDFNKAAEVKY
                     GEIPKLEEQIKQYEENMNDGSENSLLKEEVTEEEISSIVSKWTGIPVTKLVEGEREKL
                     LKLEDELHKRVIGQDEAVTAVSNAVIRARAGLKDERKPIGSFIFLGPTGVGKTELAKT
                     LARNLFDSDDNIIRIDMSEYMEKHAVSRLVGPPPGYVGYEEGGQLTEAVRRAPYSVIL
                     FDEIEKAHEDVFNMFLQILDDGRLTDNKGKTVDFKNTLIIMTSNIGSNYLLEAGGNIT
                     ETTNNLVMNEMKHRFKPEFLNRVDDIIMFKPLDQENIKKIIDIFMKDLKNRLKEKDIT
                     IEVTNSAKDVMVREGYDPVYGARPLKRYIGNTLETIIAKKLIAGDVYNGCTIVIDGKD
                     ENIEVLVK"
     gene            complement(5606..6202)
                     /locus_tag="JAM15_14695"
     CDS             complement(5606..6202)
                     /locus_tag="JAM15_14695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799502.1"
                     /translation="MSLKLDRNVLQWFDYVFENEKTSLRHYNFNCTLKEISSTSLNKV
                     AFILEKNNSKYWKLYFEIPAEVTLKLKQNIHPLFREYIYEQISLYNNNQIYNFVNSNI
                     LKVFNNIAIYQYNILENLYTIDFKKSFIDKCQYLLIGEKRLIDEDLYLIAKSKEVFDF
                     FNSDGTFNLTLSFDIQKNENLLDSLLELRKSIIINERI"
     gene            complement(6219..6623)
                     /locus_tag="JAM15_14700"
     CDS             complement(6219..6623)
                     /locus_tag="JAM15_14700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid replication protein"
                     /protein_id="HAT6799503.1"
                     /translation="MDKTLKKDLNQEYTESKSLVMNKSKYMNICFKNYIKVVEGMYTK
                     RDLIPLKLINSMDKNNKIRKTLYELSCEFEYPKTSLSSLFTELKKMDFLQRVKNGEYM
                     INPHIAYKGSRADKESLLAEYNQIKRPNKVSK"
     gene            6990..7364
                     /locus_tag="JAM15_14705"
     CDS             6990..7364
                     /locus_tag="JAM15_14705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014793690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAT6799504.1"
                     /translation="MNIVISNSSGKPIYEQITTQIKSMIISGELPEGSALPSMRLLAK
                     ELRISVITTKRAYSDLERDGFIETVTGKGSFVSSKNMDFVKEEQFRLIEEYLQKAVDT
                     AKSSDITYDELKDILFLLYKGE"
     gene            7370..8224
                     /locus_tag="JAM15_14710"
     CDS             7370..8224
                     /locus_tag="JAM15_14710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6799505.1"
                     /translation="MDAITIKNLNKTYKDFSLQDISFSVPKGSVMGFVGENGAGKTTT
                     LKAILNLISYDSGNIEIFGLDSKKNEKEIKEQIGVVFEGSNFHENLNTDHVSKIMSKI
                     YKNWNDTLFKDYLKKLRVPDNKLIKEFSKGNKMKLSIAVALSHKPKLLILDEATSSLD
                     PIVREEILDIFLDFIQDEEHSIILSSHITSDLDKIADYITFIHKGKIVFSENKDELID
                     TMGVLKCKPSDFDNLSREDYSYYRKSQFGYEVLLKDKHRFISRNPNCIVDNTSIEEIM
                     LFYVRGDK"
     gene            8224..8862
                     /locus_tag="JAM15_14715"
     CDS             8224..8862
                     /locus_tag="JAM15_14715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HAT6799506.1"
                     /translation="MKGLILKDLLNLKGNVKFILLFIIMFGFMSSLGDGNVNNFIGVI
                     IVLCTTMIVSTFSYDDLNKWDSYVLTMPINRNDIVLSKYLTMLIFSFIGVLVSLIVSV
                     TIGYFKNTLILNETLLINALILSISVCFGSLILPLIYKFGTERARLLMILCFLVPTLA
                     LLVFKSILENISSPISIEIILNTLVYSLPFVAILLFVISYFISSKIYSKKEV"
     gene            9355..9768
                     /locus_tag="JAM15_14720"
     CDS             9355..9768
                     /locus_tag="JAM15_14720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017353736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAT6799507.1"
                     /translation="MELEITEKIEKQDEDTIFQGLLKYNLARLEDKNPVDLGIYIRDK
                     AGKIVAGFIGVTHGNWLSIKYLWVSEKLRYKGTGSQLLYKAEKIAKERGCKYVFLDTF
                     SFQAPKFYDKFGYHKVFSLENYPLTGKRYYFRKIL"
     gene            9959..10804
                     /locus_tag="JAM15_14725"
                     /pseudo
     CDS             9959..10804
                     /locus_tag="JAM15_14725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428929.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallo-hydrolase"
     gene            complement(10995..11381)
                     /locus_tag="JAM15_14730"
     CDS             complement(10995..11381)
                     /locus_tag="JAM15_14730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HAT6799508.1"
                     /translation="MKISKLPEAELKVMRYIWESDKILTSREITEAMEQKYEWKDTTT
                     FTVLKRLQRREFLETEKIDKRTHYNVLVKEKQYQRFETREFIKNIHKNSIKSLISALH
                     KDDEKVDEKKLDELEEYFNNLEENEK"
     gene            complement(11486..11863)
                     /locus_tag="JAM15_14735"
     CDS             complement(11486..11863)
                     /locus_tag="JAM15_14735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HAT6799509.1"
                     /translation="MKEEVLIEKLLRAELIVMEYLWKKDYLMPKKEIVKEMRQVCGWH
                     KSTIKILLKRLVEKGYLARDIIKFQSHYKIIIDNEEYYAFKKKVLKSSKSRKIMRSLT
                     TTHKNVSKEKLDSLEEYYKNLKE"
     regulatory      12072..12168
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(12892..13098)
                     /locus_tag="JAM15_14740"
     CDS             complement(12892..13098)
                     /locus_tag="JAM15_14740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAT6799510.1"
                     /translation="MISYNRLWKLLIDKKIKKMEFKEMTGLGSSSISKLKEDKVVSMA
                     TMEKICLALDCNIEDIVEIKKDGE"
     gene            13267..13710
                     /locus_tag="JAM15_14745"
     CDS             13267..13710
                     /locus_tag="JAM15_14745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424162.1,RefSeq:WP_009905657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799511.1"
                     /translation="MIKFEVGKTYATRSICDHDCVYTIEVIRRTNKTLTYQESNNIKR
                     VKIRFTEDSEYIKLGNYSMAPVFYANKKSIEEKKKSVSNVENKTIVEKYFVISRYYNS
                     GKTIAFIEINSTKYKTEYIRNFDQYVDEFSTLEEAEKCLQECLSA"
     gene            13723..13929
                     /locus_tag="JAM15_14750"
     CDS             13723..13929
                     /locus_tag="JAM15_14750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799512.1"
                     /translation="MCFKTYVLKRLVNNKQLEITRSFDLDNLICTATEILKDNEIDLI
                     IIDEKNEVVWKSKKSIPYDRKCSL"
     gene            complement(14221..14649)
                     /locus_tag="JAM15_14755"
     CDS             complement(14221..14649)
                     /locus_tag="JAM15_14755"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799513.1"
                     /translation="METKKIDKDYIESLLKKLIDEYHINENIISNLLEIETEKLKSYK
                     KYEKEFTVDLDIWSKWINFVLQLEYIIDVDSDSRLRGILSLLINVYEINIEFIARTAH
                     IEEKYLIDFINGEDYLSTEIKYKICATVMSLSLLFKNTEK"
     gene            complement(14668..15174)
                     /locus_tag="JAM15_14760"
     CDS             complement(14668..15174)
                     /locus_tag="JAM15_14760"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799514.1"
                     /translation="MSKVFKKLTGILSAVLLVASMSITSFAYDSETQEKEYVVNVAGK
                     EIKLKEGEEIVIPLVDPNVDPNKISTREIFEGNTGKLSLTAGSKTVNYKITMFIPAAR
                     FSGAVNVTNVSHGGSSSSNRVTGFSGSVPYRALSGCRYSAIVTGAAYDLGGKVVARVV
                     PNLITWVR"
     gene            15421..15885
                     /locus_tag="JAM15_14765"
     CDS             15421..15885
                     /locus_tag="JAM15_14765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799515.1"
                     /translation="MDFGEVKQDLSNKYLEDNKENLNKYKKYYLKVYKHYSEMDSIKS
                     IRDIEIEQARLKGQLQKNNNPIFALYISIMAVVFSTIINLTFDLSDIANYFIKSAMTF
                     ALIVILTILVNKGIVPIAIPYRNNIQFYTTALEVLESMKNEKLRERKYKKRR"
     misc_feature    complement(15478..15536)
                     /note="possible 23S ribosomal RNA but 16S or 23S rRNA
                     prediction is too short"
     gene            complement(15914..16711)
                     /locus_tag="JAM15_14770"
     CDS             complement(15914..16711)
                     /locus_tag="JAM15_14770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAT6799516.1"
                     /translation="MKIAIVPGHTLSGKGTGATGYIDEGKENRILTDLIVKWLKQGGA
                     TVYTGKVDKSNDYLAEQCQIANKQDVDLAVQIHFNANKTTLNPIGTETIYKTNNGKVY
                     ANRVNDKLATVFKNRGAKSDVRGLYWLSHTKAPAILIETCFVDSKADTDYYIRHKDTV
                     AKLIAEGILNKKIDNIEVKQMYKHTVVYEGEVDKVLAQIISWNYKENECRVCDIKDYV
                     PGQTENLYIIGGGACNKIGSITKERYTMIKGNDRFDTLYKALDFINR"
     gene            complement(16711..16968)
                     /locus_tag="JAM15_14775"
     CDS             complement(16711..16968)
                     /locus_tag="JAM15_14775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin"
                     /protein_id="HAT6799517.1"
                     /translation="MDNLISFIPEQLLILVAALSIIGKGCKKYKQLDNKYIPIILLVL
                     GIGFSIWMLGFSPNAVLQGVICWGISIGINQTYKQLKDGEK"
     gene            complement(16972..17262)
                     /locus_tag="JAM15_14780"
     CDS             complement(16972..17262)
                     /locus_tag="JAM15_14780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799518.1"
                     /translation="MEEISINLLCAVAGVIISYLAFRNNSNRKIQDETETTTKLEQQI
                     TFLCENVRDIKHDVAKFNTSFLDISERVAKVEASTKQAHLRIDEIINRIGGK"
     gene            complement(17316..17993)
                     /locus_tag="JAM15_14785"
     CDS             complement(17316..17993)
                     /locus_tag="JAM15_14785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799519.1"
                     /translation="MTFKELVNKVRNLVLEAKNVTIEDTENKFTSENVEGALKECIDR
                     ADEAFQEADSGKILLSTAIGSPATSEQTFQEYADYITEFKGTISTLTTKLESASNKLT
                     DPYITKVSNKGVPSTFTVDFRMYYPSSSFTRRSTCIYVDATFIHYTTPGDMSTGVHKS
                     VKCVKTDTKDLNSYQIFYDGGGILDLTYEDDSVRVIIQGGYTSSPGRKRSDVYSYNVR
                     MVNTYWD"
     gene            complement(18027..18209)
                     /locus_tag="JAM15_14790"
     CDS             complement(18027..18209)
                     /locus_tag="JAM15_14790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799520.1"
                     /translation="MNINNIVVRILADRILNGGLNPLKNREFQLDDVTNTEYRKAVED
                     YIIKNSGVVEGAEPTI"
     gene            complement(18209..18514)
                     /locus_tag="JAM15_14795"
     CDS             complement(18209..18514)
                     /locus_tag="JAM15_14795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799521.1"
                     /translation="MNDYIEVGRRIFFDEEGEIIFYEGQSKGNVPERKNIKKIEYIDL
                     EYDYVDYDKYKIKGINIETKQPILEEIPIYMSEEEKRIQELENQILIAENEKVGGLL"
     gene            complement(18526..19137)
                     /locus_tag="JAM15_14800"
     CDS             complement(18526..19137)
                     /locus_tag="JAM15_14800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799522.1"
                     /translation="MIEKLNENASLSDLITTFENSTKELKASKDNFTNLLGNPFLEST
                     KFTEFEGKMQNLMNTFKENLKSKGVNSGNTESLLSLINKVDNIHIPTPIYTASGECII
                     DSKGTCKRYTISTNGDVYYVRINLNFYPKLVVMYNTGGASKYFTTSYFCSYVPFIAST
                     VESYTTYLLDKSDSNIQVQKGTCILPIVYSKYGSSSFYFYAIG"
BASE COUNT         6429 a         2842 c         2271 g         7649 t
ORIGIN      
        1 atcatactat tttagctgtt tacttgctta tttgatagtt ttatttcttt gattaaatat
       61 ctttcagaat ctaagccaga tgtctcaaaa aaactgattt ataatataat cattttttct
      121 gctattctta tttttccaat tttagtttca tattaaaata tacttttcat agacactaca
      181 ttctttcata ctcattttca catttaacta tataagtagt cttactcatt tatgtactat
      241 actttattaa tatttattaa gaaaaactca aagatttaaa aatatatatt ttctataaag
      301 tatatttatg aattatttca tatcttcttt taaaataaca ttactaactt ctctatgttc
      361 atttctatac ttagttggag atatattata attcctttta aataagcgac taaaataatt
      421 tatgctatca aagccacatc tcatagcaat ttctgtcata tttaaatctg tttcctttaa
      481 ataatatata gctttatcaa gcctgattcc atttataaaa tcgattgtag tcttacctgt
      541 tatttgctta aatgttctac aaaagtgatg tgcactcaag ttcacacgac tagcaagttc
      601 ttttaatgta attttatcca tatatttttc ttctatcaag tcaaagatac attcaaattt
      661 ttctaaagaa tactttcttt ttataaattc atcttcagaa tatattttat caatatgact
      721 tcttaataag agtactatta attgatagat attagctttt atagataact catatccaac
      781 ttctttattg tgatattcat caagtatagt tgtaatacat tttaaaatca gaaaatcatt
      841 ttgaattaaa ttattaaata caatatgatt taaagccaat ggtgctaagt acttagtttg
      901 taacaaatca acttgattac taaaaaggaa tgtgggctca atacgaatac tatagaattt
      961 taaattatct gataagcttt ctaaataatg taattcatta ctgtttgcta ttacaatatt
     1021 tccaggcact accttaaaat tatccaatcc acattcaaga tatgctatac catcaataaa
     1081 ataatatatt tgtagatgct catgccaatg tcttttaaag tttgctcctt ttttaatgtc
     1141 atcctttaaa aaaatatcta taaagttttc ttgacctttc ctattaaaat atgtattttt
     1201 atccttcatt attcccccct catcaaaata gtgctaatta taagcaatat agttattgta
     1261 ttcattattt catatcgcta ttatataaaa tgtaactatc attgtaaaca ttaacataat
     1321 gccagtcatt ataataagga ggtaataaaa atgacaaact cttttaaaaa agatgataat
     1381 agaaaaaaaa tcacagtttt atttgtagtc attgccatga cttttatggc aacattagat
     1441 tcgagtatta taaatgttgc tctcccagtt cttgcaagca aactaaatgt atctctagca
     1501 tctattgaat gggtaatagc aagttactca attattattt gttcaacact attatttttt
     1561 ggaagacttg gagatattat tggtaaatca agagtattcc aagtaggtac tattctcttt
     1621 acatcagctt cattactatg tggattaagt aattctttaa ctttacttat agtttgccgc
     1681 tttattcaag gaataggcgc ttctgcctac atggcaaaca atcatggaat tatcacagaa
     1741 ctatttccaa aagaaagcag aggaaaagcc ctagggattc tagttactgc agttgctatt
     1801 ggaaatatgg ttggaccatc tgtgggagga tttattttgt caatatttga ttggaatgtt
     1861 atatttttta taaatattcc aatcggtctt attgtaatct ttttaaatac aaaatttctt
     1921 cctaatagta aaaaatcttc agaaaatatg gataaaactg gtgctatact tcaattttta
     1981 ggaacaacat tattttttag tgctctaatt agtgctcaac aaacaggatt actaaatcca
     2041 tatatattaa ttgcactatt attatcaatt atttttatta tattattttt gatattagaa
     2101 aaaaaacatc ctcaaccgct tcttgatctt gaaattttta gaaattttaa attttcattg
     2161 aatttaattt gtgctcttac atcattcatt tgtattgcat catcaagtat tttaattcca
     2221 ttttatttac aaagtactat gaaacttccc cctattcaag caggtttatt tatgatacta
     2281 tcacctttga ttttagccat tttttcacct atatttggga atatatcaga taaaatcaag
     2341 tcagaaaaaa ttattttaat tggtcttctt gttatgagtt ttggattctt tctaatgtca
     2401 agattgaaag aaagttctgc ccttatttta tttgtaattt atatatcgat aatatcaata
     2461 ggacaagcta tatttcaacc tgctaacaat gctttgataa tgtcaagctg ttctagaagt
     2521 aagctaggag ttgtaggaag cataaattcc cttgtaagaa atttaggaca agttataggt
     2581 attactattt ctacaacact tttatataat tttatgagta ttaaagctgg atatagggtc
     2641 aatgattatg tgattaataa tgataaaata tttgtatttg gaatgagaaa tgtttatatt
     2701 attgttacac ttgtttgctt aataggtgca atattaattg gcttttattt atttaaatat
     2761 aataaaaatg aacaatagtt ttttataatt atattcaaat tatgattata ttataagaaa
     2821 cttactaaaa tacttccttt gagttaaatt taatttggac atattgactt aaaaatgttt
     2881 tattaatttg ataaaatatt tcttttccta tagtttataa ataaaaatca gctgagcaaa
     2941 atatttagta tattatgctc aactgattct tttattattt aactaaaact tcaatatttt
     3001 catcttttcc atctataact atagtacatc cattatacac atctccagca ataagtttct
     3061 ttgcaattat agtttctaat gtatttccta tatatctctt aagaggtctt gctccatata
     3121 cagggtcata tccttctctc accataacat cttttgctga atttgtaact tcaatagtaa
     3181 tatctttttc ttttaatcta ttttttaaat ctttcataaa tatatctata attttcttga
     3241 tattttcttg gtctaaaggc ttaaacatta taatatcatc tactctgttt aaaaactcag
     3301 gtttaaatct atgcttcatt tcattcatta ctaaattgtt agtagtctct gttatatttc
     3361 ctcctgcttc taatagataa ttacttccta tattagaagt cattattata agagtatttt
     3421 taaagtctac tgtcttacct ttattatcag taagtctacc atcatctaat atctgtaaga
     3481 acatgttaaa tacatcctca tgtgcttttt ctatctcatc aaatagtatt acagaataag
     3541 gagcacgtct aactgcttct gtaagttgac caccctcttc atatcccacg taccctggag
     3601 gaggtccaac tagtcttgat acagcatgtt tttccatgta ttcagacata tctattctta
     3661 ttatattatc gtcactatcg aataaatttc tagcaagagt ttttgcaagt tcagttttac
     3721 caacacctgt agggcctaag aaaataaatg aaccaattgg ttttctttca tcttttaatc
     3781 ctgctcttgc acgtattact gcatttgaaa ctgctgtaac tgcttcatct tgtccaataa
     3841 ctcttttatg aagttcatct tctagtttaa gtaatttttc tctttctcct tcaactagtt
     3901 tagttactgg tatacctgtc cactttgata caatgctaga tatttcttct tcagtaactt
     3961 cttcttttaa aagagaattt tcagaaccat cattcatatt ttcttcgtac tgctttattt
     4021 gttcttctaa cttaggtatt tcaccatatt taacctctgc tgctttgttg aaatcatatt
     4081 ctctttcata cttttcagct ttacctttag cttcgtctaa ttgagccttt aagtttttaa
     4141 tatctaatat ttgactcttt tctttttcat attttgctgt catttcatca tttttagatt
     4201 ttaactctgc tatttctttt tgaatatcat ccaatcttga tttgctttta tcatcatttt
     4261 ctttaagtaa tgcttctctt tcagtttcta atgtaaataa ctttcttcta acaacatcta
     4321 attctgttgg caatgaatct atttcactac gaatcatagc tccagcttca tcaattaaat
     4381 caattgcttt atctggtaaa aatctatctt gtatatatct atgagaaagt tttgctgctg
     4441 ctacaatagc attatcatgt attcttactc catgatgtat ctcaaatctt tcttttaaac
     4501 ctctaagtat agatattgtg tcttcaacag taggttcttc tgcaattaca ggctgaaaac
     4561 gtctttcaag agccttatct ttttctatat actttctata ttcatcaaaa gtagttgcac
     4621 caatacagtt caattcacct cttgcaagca taggtttaat aagattacct gcatccattg
     4681 aaccttctgt tttaccagct ccaacgatag tatgaatctc atctataaac agtataatct
     4741 ttccatcaga actttgaact tcttttaaaa ctgcctttaa tctttcttca aattcacctc
     4801 tatattttgc accagcaatt aaagctccca tatcaagtga gaatacaatc ttatctttta
     4861 aaccttctgg gacatctcct cttactattc tctctgctaa cccttctaca attgcagttt
     4921 tacctacacc tggctcacca atcaatacag gattattttt tgttcttctt gataaaattc
     4981 ttataatcct tcttatttct tcatctctcc caattacagg gtctaattta tttttcttgg
     5041 ctaaatctac taagtttgtt ccatatctag caagtgcatc atatgtgcct tctgggtctt
     5101 gtgtttctac tctttgacta cctctcactt gtgataaaat atttaaaaag tcattcttat
     5161 ttatattata ttgttttaat attttaccaa cagctgattt tgattctgtt tccatcattg
     5221 caagcataac atgctctaca cttatatatg aatctttaaa ttctttagaa atactctctg
     5281 cctttataag cacctcattt atttttctag tagctgatac tccttgtgag tcagcacctt
     5341 ctccatatac ttttggaagc ttatcaattt caaagtttac agtatttctc aaagaatcaa
     5401 ttggtatatt cattttttcg attatatttg gtatcaatcc atcctcttga ttaataagtg
     5461 ctgagaaaag atgaattaca tctacttgtt ggttatgatt ttttactgct tcgttataag
     5521 cctcatttaa acttttttga actcttaaag tcattttttc tacgtccata taaatccctc
     5581 cattttaata ttatatccaa ataaattaaa ttctctcatt tataattatt gattttctaa
     5641 gctctaaaag actatcaagt aaattctcgt ttttttgtat atcgaaactt aatgttaaat
     5701 taaatgttcc atctgaatta aaaaaatcga atacttcttt tgattttgct attaaataca
     5761 agtcttcatc tataagtctt ttttcaccta ttaataaata ctgacattta tctataaaac
     5821 tctttttaaa atcaatagtg tatagatttt ctaaaatatt atattgataa atagcaatat
     5881 tattaaacac ttttaatatg tttgaattta caaaattgta aatttgatta ttgttataca
     5941 gtgatatttg ttcgtatata tattccctaa ataaaggatg aatgttttgc ttaagtttta
     6001 aagtaacttc agctggtatt tcaaaataaa gcttccagta cttagagtta tttttttcta
     6061 aaataaaagc tactttgttc aaactggtag aactaatctc ctttagtgta caattaaaat
     6121 tatagtgtct caaactagtt ttttcattct caaatacata gtcaaaccac tgtagaacat
     6181 ttctatcaag ttttaaactc atataaaaac cttcttcctt atttactaac cttattaggt
     6241 ctttttatct gattatattc tgctaataaa ctttctttat cagctctact acctttatat
     6301 gctatatgtg gatttatcat atactcacca tttttcactc tttgtaaaaa atccattttt
     6361 ttcagctccg taaacaatga agataaagaa gtttttggat attcaaattc acaagataat
     6421 tcatataatg tttttctaat cttattattt ttatccatag agtttattaa ttttaatgga
     6481 attaaatccc tcttagtata cattccttct actactttaa tataattctt aaaacaaata
     6541 ttcatatact tacttttatt cataactaaa cttttgctct ctgtatattc ctgatttaaa
     6601 tcctttttta atgtcttatc caaattaaat atctcttctc actctcctta tctctaattg
     6661 ataatataaa tatattacaa aaaaatatgt atgtcaaaac tgaaaatgca aaaagtttac
     6721 cttataagta aacttttatt tagctataag ctaaacttca ttattttttt aatttagtat
     6781 ttccaattta ttggcaggat ttttgaataa tatttataaa ttttttaaaa aaatttaaat
     6841 ctatttaata tggcagcctt tcataaaata cattacattt attaaatgta taatattggt
     6901 aattagtttt ttctaaaatc agttgacata ttatatatat atttatataa tgtgtatata
     6961 ctatatatac aatttaagga ggtgacttat tgaatatagt tattagtaat tcgagtggga
     7021 agccaatata tgaacagatt actacacaaa ttaaaagtat gattataagt ggagagttac
     7081 cagaaggctc agctcttcca agtatgagac tattggcaaa ggaacttaga ataagtgtaa
     7141 ttactacaaa acgagcatat agcgatttag aacgagacgg atttattgag acagttactg
     7201 gtaaaggcag ttttgtatct agtaaaaaca tggattttgt caaagaagaa caatttcgtt
     7261 taattgaaga atacctacaa aaagcagttg atacagcaaa aagtagtgat attacatatg
     7321 acgaattaaa agatatttta tttttattat ataaaggaga atgataagta tggatgcaat
     7381 aactataaaa aatttaaata aaacttataa agattttagc ctacaagata tatctttttc
     7441 agtaccaaaa ggaagtgtaa tgggctttgt aggtgaaaat ggtgcaggaa aaacaactac
     7501 attaaaagca attttaaatt taatatctta tgatagtgga aatatagaaa tctttggtct
     7561 tgatagtaaa aaaaatgaaa aagaaattaa agagcaaatt ggggttgtat ttgagggaag
     7621 caactttcat gaaaatttaa acactgacca tgtttcaaaa atcatgagta aaatctataa
     7681 aaattggaat gacacattat ttaaagacta cttaaaaaaa ttgagagtac cagacaataa
     7741 attaattaag gagttttcaa aggggaataa gatgaaactt agtattgctg tagccttatc
     7801 tcataaacca aaattattaa tactagatga ggcaactagt tcacttgatc ctatcgttcg
     7861 tgaagaaata ctagatatat ttttagattt tatacaagat gaagaacact ctattatctt
     7921 atcttcacat attacaagtg atttagataa gatagcagac tatattacat ttatacataa
     7981 aggaaaaatt gtatttagtg aaaataagga tgaattaatt gatactatgg gagttttaaa
     8041 atgtaaacct agtgattttg ataacctttc aagagaggat tattcatatt atcgtaaaag
     8101 ccaatttgga tatgaagtac ttcttaaaga taaacataga tttatatcaa gaaatccaaa
     8161 ttgtattgtt gataatacgt ctatagaaga aattatgtta ttttatgtga gaggtgataa
     8221 ataatgaaag gtttaatttt aaaagattta cttaatttga aaggaaatgt aaagtttata
     8281 cttttattca tcattatgtt tgggtttatg tcttctttag gagatggaaa tgttaataac
     8341 tttataggtg ttattatagt tttatgtact acaatgattg tttcaacatt ttcatatgat
     8401 gatttaaata aatgggatag ttatgtactt acaatgccta ttaatcgcaa tgatattgta
     8461 ttaagtaaat atttaactat gttaatattt agctttatag gtgttcttgt ttcacttatt
     8521 gttagtgtaa ctattggtta ttttaaaaat acacttatat taaatgaaac actacttatt
     8581 aatgcactaa tcttatcaat ttcagtatgt tttggtagcc ttattctacc acttatttat
     8641 aaatttggta cagaaagagc tcgtttatta atgattttat gctttttagt tccaacacta
     8701 gctttattag tttttaaaag tattttagaa aatattagtt cacctatttc tatagaaatt
     8761 atacttaata cactagtata ttctcttcca tttgttgcta ttttactatt tgtgatttca
     8821 tattttatat catcaaaaat ctatagtaaa aaagaagtat aaaatatact atacatgtct
     8881 ctgtatttaa gtattttaaa taaaatacta tcaagtttat tttggtagta ttttattttt
     8941 ttattattaa tatctactag gtatttattg ttttattact tatatttaat aagactattt
     9001 actactttct aatcttattt atataattta ttcattttat aaattgaact actaatgata
     9061 ttattgaaca tagcaataga ataacatcta aaatagtttt tatgtattaa attaacttat
     9121 tttaatattc aacaatttag gtttactaaa tttattgatg atttcttttt atataactta
     9181 aactacattt ttattttaaa aaatttaata tcaacaatat aaaattaaga ataagtatta
     9241 ttagtttgac attagcataa atgcctatta gaataatgtt aaactatatt ctttctactg
     9301 attttattaa aaaataccaa tatacaaaag attatacaag gagaaagttc aaatatggaa
     9361 ttagaaatta cagaaaaaat agaaaaacaa gatgaagata ctatttttca aggattatta
     9421 aaatataatc ttgctagact tgaagataaa aacccagtgg atttaggaat atatattcga
     9481 gataaagcag gtaaaattgt tgcaggtttt ataggtgtta ctcatggtaa ttggctttct
     9541 ataaaatact tatgggttag tgagaagctt agatataaag gtactggaag tcaactttta
     9601 tataaggctg aaaaaattgc taaagaacga ggttgtaaat atgttttttt agatacattc
     9661 agttttcaag cacctaaatt ttatgataaa tttggatacc ataaagtatt ttcacttgaa
     9721 aattatcctc taactggaaa gagatattat tttagaaaaa tactataata ataaaaatca
     9781 tattttatat ttttaactta aaacttctgc tcttcgtcta cagactttat gttcttatat
     9841 cattattaat actaaaatag tattttacta tacatacaaa attatttgaa agttcaaaaa
     9901 ttataagtat aaaagctaat cttagcttaa ataaaaatta tatttttagg aggtaaatat
     9961 gttaggaaaa aaatgtatgg attatctaca aacattagga aaaataagtt caacaacaaa
    10021 tggtcttaca agacttatct tgactcaaga acataaaaaa tctattgatt taattagttc
    10081 atggatggaa ggtttaaatc ttgatattga aattgatgac attggaaacg ttataggtac
    10141 atataaatca agctttccaa atgctcccac attagtagtt gcatctcatc aagatagtgt
    10201 aaagtgtgga ggtatatttg atggtatgtt aggtataata gtgcctctag ttggtcttga
    10261 agaagcaaaa cacaataata ggtcttatcc tttcaatatt aagctaattg ctttcgctga
    10321 agaggaagga actagatttg aaacttcttt aatgggaagt aaagtttttg ctggtacttt
    10381 taaagaggaa cttcttaaat ctgttgatga aaatggaatt acacttgaag aagctgtaac
    10441 aaagtttgga tttaatacaa aaaacttaac aaatttgcat cctagaaaag atgtagatgc
    10501 atatttagaa tttcatatcg agcagggtcc tgttttagaa aatgaatctc ttcctgctgg
    10561 aattgtatca agtattacag gatttaaaag ttttaagata tcagtaaatg gtaagtctgg
    10621 acatgctggt acacttccaa tgaatatgag acttgatgct ggatgttgtg cctgtgaatg
    10681 tgtattagct atcgaaaaag tagctaaaac gactgctgat ttggttgcta ctgtaggaaa
    10741 gatgaatttc tatccatctt catcaaatgt ggtacctgaa agagctgaat ttacactcga
    10801 aattctcata ttttctttat gcttatttat atttatttat gtttttatga atacatctat
    10861 tttcaattca tctaaaacga tttctttatt ttattttctt tatgcttctt tatttgtatt
    10921 ttattttatt aaaccagttt ggtggcaaat gggtggcaaa aacaatttgc cacccatttt
    10981 ttctttgtaa aattttattt ctcgttttct tctaaattat tgaaatactc ttctagttca
    11041 tctaattttt tttcatctac tttctcatca tctttatgta atgctgaaat caaactttta
    11101 attgaatttt tatgtatatt ttttataaat tctcttgttt caaatctctg atattgtttt
    11161 tcttttacta atacattata gtgtgtacgc ttatctattt tctctgtttc taaaaactct
    11221 cttctttgca atctttttaa tactgtaaat gtagttgtat ctttccattc atatttttgc
    11281 tccatagcct cagtgatttc tcttgatgtt aatatcttgt ctgattccca aatatatctc
    11341 ataactttta attccgcttc tggtaattta ctaattttca tagtctacac ccctttaccg
    11401 atttatgtat atgttaaatt ctatatcaat aaagttttac aaacaagaga attaagataa
    11461 ataattccat ccaattttta ccaaatcatt cttttaagtt tttatagtac tcttctaatg
    11521 agtctaactt ctctttactt acatttttat gcgtagtggt aagtgaacgc attatttttc
    11581 tacttttact agattttagt acctttttct taaaagcata atattcttca ttatctatta
    11641 ttattttata atgagattga aattttataa tatctctagc caaataacct ttttcaacta
    11701 gcctttttag cagtattttt attgtacttt tatgccatcc acaaacctgt ctcatttctt
    11761 ttacaatttc ttttttaggc attagataat cttttttcca taaatactcc attactatta
    11821 attctgctct taataatttt tctattagta cttcttcttt caatttatgt cacttcctta
    11881 attcgtctaa cttaaattaa taataggagc tttttaagac aaaaactaga ggtaagtttt
    11941 accaaatatt ctactctttt agtttgtttt cttagaagaa aaataacttt catatctata
    12001 aaattattca actttcaaac tatcctgttg aataataact aattctattg tattatttta
    12061 gttgtagaat aaaactaaat cggcaaaact agagaaattt agtgacgcaa agctataggg
    12121 actaagactt atagagcatc ttatgagtta tgtcagccag ttgccaaaaa gatatattct
    12181 ttttgttttt atgaaagttt tttaggggga taataatata tatgtttaga gataaaatgg
    12241 atagatgtac acacatgttg actgcttata ttggtagttc atatgattat tgtgatttta
    12301 tagatacaca actagatgat tttatactag agtatggaga aaatgtagta gagtcttgct
    12361 tacatcaagt gatggtattg gtaagtaagt ataattagat agatattgtt ttctagaaca
    12421 ccctttttag ttttatctac atttaaagat tattatgtta aaaaattaaa atatatttat
    12481 aatattcata gttttatttt ttgttaaaat gcgatataat aaagatgtaa aatcgtatca
    12541 aaaataaaaa agaaactaca atctattagc ctagagcgaa gtttcaaatt caaaataatt
    12601 taagtaatga tttattcatt gaaatcgtct tgattgccgt caggacgatt tcttagttta
    12661 tgtaaagatt cttttaattt acttatagaa tctaataatc ttgttataga ctttactgtt
    12721 gttgtaatag attttattat aatagtaata taatacgcta taacaagtat aaacataagt
    12781 gttttcatat actcacccct tttcatacga aggtgatttc tgaaaacttt cgcccttaga
    12841 ttgtagcctc ttgcatttta attataacat aattttacaa ttatcaaata tctattctcc
    12901 atctttttta atctcaacaa tatcctctat gttgcaatct aatgctaaac atatcttttc
    12961 cattgttgcc attgaaacaa ctttatcctc ttttaatttg ctgatacttg aacttcctag
    13021 tcctgtcatt tctttaaatt ccattttttt tattttttta tcaattaata atttccataa
    13081 tcggttgtat gaaatcatgt tatcaactcc ttataattat tttatcataa ttaacctgtt
    13141 aagggcaata tttctctttt atagttaatt tcgcttgact ttattcttaa atagtagtat
    13201 tattttatta accttaaaag gttaatatta actatttaag aaaaataatt aaaggagtgt
    13261 attaaaatga taaaatttga agtaggtaaa acttatgcaa caagaagtat atgcgaccat
    13321 gattgcgtat acactataga ggttatcaga agaactaata aaactctaac ttatcaagag
    13381 tctaacaata ttaaacgtgt taaaattcga tttactgaag actctgaata cataaaatta
    13441 ggtaactata gcatggctcc tgttttctat gctaataaaa agagcataga ggaaaagaaa
    13501 aaaagcgttt ctaatgttga aaataaaact attgtagaaa aatattttgt gataagtaga
    13561 tattataata gcggaaaaac tattgctttt atagaaataa atagcactaa atataagact
    13621 gaatatatta gaaactttga ccagtatgta gacgaatttt ctacattaga agaagcagaa
    13681 aaatgcttac aagaatgtct tagtgcttaa gaggtgatat aaatgtgttt caagacttac
    13741 gtactaaaaa gacttgtaaa taacaaacaa ctagagataa ctcgaagttt tgacttagat
    13801 aatctcattt gtactgcaac agaaatattg aaagataatg agattgattt gataattatt
    13861 gatgaaaaaa atgaggttgt ttggaaaagt aaaaagagca tcccttacga cagaaaatgc
    13921 tctctttaat atggttaact tagtaaagat ggattggatg ttcatcttta ctttttttat
    13981 tatatcatat aatttactct atgaaaaaga cctatttaaa tcgtttctaa gatatgttga
    14041 gtaaggttat tgataagttt ttatacattt aatgtatttc aaaaaataag cactcttttt
    14101 ataagagtgc tttggtgtat gttaatgtat atatctgata caatttttct tatgttttag
    14161 tatgataatt ttcgttcgtt ttattattat aacttatact ataagttttt aactatccat
    14221 ttacttttct gtatttttaa acaataaact caaactcatg acagtagcac atatcttata
    14281 ctttatttct gttgatagat aatcttctcc atttataaag tctattagat atttttcttc
    14341 aatatgtgca gtcctagcta taaactcgat attaatttca tatacattga ttaaaagact
    14401 taagatacct ctgagtctag agtcagaatc aacatctata atatattcaa gttgcagaac
    14461 aaaatttatc catttagacc atatatctaa atctactgta aattcttttt catacttttt
    14521 atagcttttc aatttttctg tttctatctc aagtaaattg gatataatat tttcatttat
    14581 atgatattca tctattaatt tcttaagaag agactctatg taatccttat ctattttttt
    14641 tgtttccatc aaattctcct ctttaaatta acgaacccat gtaattaaat taggaactac
    14701 tcttgcaact actttaccac ctaaatcata agcagcgcca gttactattg cactatatct
    14761 acacccagaa agtgctctat atggtacaga accactaaat ccagttactc tattgcttga
    14821 agaagaacca ccatgagaaa cattagttac atttacagct ccagaaaatc tagcagccgg
    14881 tataaacatt gttattttat aattgacagt tttagaacca gctgttaaac ttaatttccc
    14941 tgtatttcct tcaaatatct cgcgagtaga tattttattt ggatcaacat tagggtcaac
    15001 taaaggaata actatttctt cgccttcttt tagttttatt tcctttcctg ctacattaac
    15061 tacatattct ttttcttgtg tctctgaatc atatgcaaaa gaagttatag acatagatgc
    15121 aactaataaa actgctgata atattcctgt taatttttta aatacttttg acataaaaac
    15181 ctcctatgat ttaaattaat tatttttgaa atcgatttct tctttattct attataatag
    15241 agtttataag tcaacacatt attctatgag gatagaataa tgtgttatgt acaagctttt
    15301 aaaatacttg cattaagtct aaatattttt tcatctaaaa tcgttcgaca aattgctgat
    15361 ataagttctt aaatatgcta taaattaaag tatactatat aacaatctag gaggaatagt
    15421 atggattttg gagaggttaa acaagattta agtaacaaat atcttgaaga taacaaagaa
    15481 aacttaaata agtataaaaa atattattta aaggtttata agcattatag tgaaatggat
    15541 tctataaaaa gtattcgaga tatagaaata gaacaagcta gacttaaggg tcaattacaa
    15601 aaaaataata atcctatatt cgctttgtat atatctataa tggctgttgt tttttctaca
    15661 ataattaatt taacgtttga tttatcggat atagctaatt attttattaa atcagcgatg
    15721 accttcgcac ttattgtgat tcttactatt ttagttaata aaggaatagt tccaatagct
    15781 ataccttata gaaataatat acaattttat acaacagctc tagaagtact agaaagtatg
    15841 aaaaatgaaa aactcagaga aagaaaatat aaaaaaagaa ggtaacaact aactctagtt
    15901 gctacctttt aatctatcta ttaataaaat ccaatgcttt ataaagtgta tcaaacctat
    15961 catttccctt tatcatagta tatctttctt tagttataga acctatctta ttacatgctc
    16021 ctccacctat aatgtataaa ttctctgtct gacctggtac ataatctttt atatcacata
    16081 ctctacattc attttctttg tagttccagc taattatttg tgctaatacc ttgtcaactt
    16141 ctccctcgta aactactgta tgcttataca tttgtttcac ctcaatatta tctattttct
    16201 tatttaatat accctcagct attagttttg caactgtatc tttatgtcta atataataat
    16261 ctgtatcagc cttactatct acaaaacaag tttcaattaa tattgctggt gcttttgtat
    16321 gactaagcca atacaagccc cttacatctg attttgcacc tctattttta aatactgtcg
    16381 ctaatttatc atttactcta tttgcataca ctttgccatt attagttttg taaattgttt
    16441 ctgtacctat tggatttaag gttgttttgt tggcattaaa atgtatttgt acagctaagt
    16501 ctacatcttg tttattagct atttgacatt gttctgctag atagtcgtta gatttatcta
    16561 ctttcccagt atatacagta gctccacctt gtttcaacca ttttacaatt aaatcagtta
    16621 aaattctgtt ttcttttcct tcgtctatat agccagttgc tcctgttcct tttccactta
    16681 aagtgtgtcc tggtactatt gctattttca ttacttttca ccatccttca actgtttgta
    16741 agtttgattt atacctattg atattcccca acaaattaca ccttgtaaga ctgcgttagg
    16801 actaaaccct agcatccaaa tggaaaatcc gattcccaac acaagtaata taattggaat
    16861 atatttgtta tctagttgtt tatatttttt gcaaccttta cctataatag agagagcagc
    16921 cactaaaatt agcaactgct cgggtatgaa acttattaaa ttatccatct tttattttcc
    16981 tccaattcta tttataattt catcaattct aagatgtgct tgttttgtac ttgcttctac
    17041 ttttgcaact cgttcactga tatctaagaa acttgtatta aactttgcta catcatgctt
    17101 tatatctctt acattctcac ataaaaaagt tatttgttgt tctaattttg tagttgtttc
    17161 tgtttcatct tgtatctttc tgtttgagtt atttctaaat gctaagtagg atattatcac
    17221 tcctgctact gcacataata gatttatgct tatttcttcc atacatcctc ctattttgta
    17281 ttaaaaaaac tatgctatat ttttcaatat ctttatcaat cccaataagt atttaccata
    17341 cgaacattat aagaatatac atcagacctc tttcttccag gtgaacttgt atatccgcct
    17401 tgtataataa ctctcacaga atcatcttca taagttaaat caagaattcc gccaccatca
    17461 taaaatattt gataactatt caaatcttta gtatcagttt taacacattt aacactttta
    17521 tgaacacctg tgctcatatc ccctggtgta gtatagtgaa taaaagtagc atcaacatag
    17581 atacaagtac ttctacgagt gaatgatgat gatggataat acatgcgaaa atcaactgta
    17641 aaagtacttg gaacaccttt gttacttact tttgtaatat aagggtctgt cagtttattg
    17701 ctagcacttt caagtttagt agtcaatgta cttatagtac ctttaaattc tgttatataa
    17761 tcagcatact cttgaaatgt ttgttctgat gtagcaggag agccgatagc agttgataaa
    17821 agtattttac cactatcggc ttcttgaaaa gcctcatctg ctctatctat acattctttc
    17881 aatgctcctt ctacattttc actagtgaat ttattttctg tatcttctat agttacattc
    17941 tttgcttcta atacaagatt tctaacttta ttaaccaact ctttaaaagt catttagtca
    18001 ccttctttca ataaaaaaag aaccctctat atagttggtt ctgctccttc tactactcca
    18061 ctatttttta taatataatc ctctacagct tttctgtact ctgtattagt cacgtcatct
    18121 aactgaaatt ctctattttt caatgggttt aaccctccgt ttaatattct atctgctaat
    18181 attcttacta caatattatt tatattcatt ataataatcc tcctactttt tcattttctg
    18241 caatcaatat ttgattttct aattcttgta ttctcttttc ttcttcactc atatagattg
    18301 gtatttcttc taaaattggc tgtttagtct ctatatttat accttttatt ttgtacttat
    18361 cataatcaac ataatcgtat tccaaatcta tatattctat ttttttaata ttttttcgct
    18421 ctggaacatt tcctttcgat tgtccttcat agaatattat ttcgccttct tcatcaaaaa
    18481 atattcttct tcctacttct atataatcat tcataaaatc accccttaac ctatagcgta
    18541 aaaataaaaa ctagaactac catatttact gtaaactata ggtaaaatac atgttccttt
    18601 ttgaacttgt atattactat cgcttttatc aagtaaataa gtcgtataac tttctactgt
    18661 tgaagcaata aaaggaacat aactacaaaa atagctagtt gtaaaatatt tactagctcc
    18721 gccagtatta tacataacga cgagtttcgg ataaaaattt aagttaattc taacgtagta
    18781 aacatctcca ttagtactaa ttgtatatct tttgcatgta cctttactat caataataca
    18841 ctcgccactt gctgtatata ttggcgtagg tatatgtatg ttgtcaactt tattaattaa
    18901 agacaataaa gactctgtat taccactatt tacgccttta ctttttaaat tttctttaaa
    18961 agtgttcata agattttgca ttttaccctc aaactctgta aatttagtac tttccaaaaa
    19021 tggattgcct aacaaatttg taaaattatc tttacttgct tttaattctt ttgtactatt
    19081 ttcaaaagtg gttattaagt cacttagact agcattttcg tttaattttt ctatcataaa
    19141 aaatatcacc tttctacttt cttagtaacc atttgtcaag aaagagttac t
//
LOCUS       DACTZW010000080        18946 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.080, whole genome shotgun sequence.
ACCESSION   DACTZW010000080 DACTZW010000000
VERSION     DACTZW010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18946)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18946)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18946
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.080"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(1..395)
                     /gene="tnpA"
                     /locus_tag="JAM15_14805"
                     /pseudo
     CDS             complement(1..395)
                     /gene="tnpA"
                     /locus_tag="JAM15_14805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439244.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(963..1166)
                     /locus_tag="JAM15_14810"
                     /pseudo
     CDS             complement(963..1166)
                     /locus_tag="JAM15_14810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860778.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
     gene            complement(1166..1495)
                     /locus_tag="JAM15_14815"
     CDS             complement(1166..1495)
                     /locus_tag="JAM15_14815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1904 domain-containing protein"
                     /protein_id="HAT6799523.1"
                     /translation="MPQIKIRGINENDICKISEKMINDLVEAVKCPRDYFEIECIKSV
                     AIRDGKIADVYPFVEVAWFDRGQEVQDIVARIITDSIRNNLDVESMDLAFTVFEKEKY
                     YENGEHF"
     gene            1825..2751
                     /gene="fba"
                     /locus_tag="JAM15_14820"
     CDS             1825..2751
                     /gene="fba"
                     /locus_tag="JAM15_14820"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-1,6-bisphosphate aldolase"
                     /protein_id="HAT6799524.1"
                     /translation="MALITTKEMFKKAYEGGFAIGAFNISDLEQLQGVLKAAKAKNSY
                     VMIQASMSAVKYAGPHTLVEMVKAASDEIGVDVALHLDHGPNMDAIKTCIDAGFSSVM
                     IDGSHFDFEENVRITKEAVEYAHSKGVVVEAELGVLAGTEDDVTSDVHKYTQPAEAVE
                     FVERTGVDSLAIAIGTSHGAFKFKGEAKLRFDILEEIQSKLPGFPIVLHGASAVDQNA
                     VATCNEFGGNIAGAKGVPVDMLRKASSMAVCKINMDTDLRLAMTAAIRKFLAENPKEF
                     DPRKYIGAGRDAIQAVVESKIDDVLGSANSIN"
     gene            complement(2886..4517)
                     /locus_tag="JAM15_14825"
     CDS             complement(2886..4517)
                     /locus_tag="JAM15_14825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HAT6799525.1"
                     /translation="MDNNLIGLIEHVENPAILCKESGEIIYCNHLIDSIFSFLDIKKP
                     RNINELDSNFDKTEILTDSKKKIAFRELRMTAHIYNMKDNNNENNIVYLFEKSLISDK
                     VIEDIIEHIDEVVVVFNKDGVIEKMNTVSDEILPFKRTEVLGRNITDLVRQGLVEEPI
                     ILNMLKVKKKIYRNIVYPDGKLIAYTAVPRWDSKGKLTGGVLTGRDISRVIKLESQIK
                     YSDISEDTEYISQSKIMDNIKKVVKRAAASDSSIFINGESGVGKEIIARTIYKYSSRR
                     DKPFIAINCGAIPNELLESEFFGYEEGSFTGAKKKGKKGLFEEANGGTIFLDEIGELP
                     MQMQKKLLRVIQENTITRIGGSKPIKIDVRYISATNISHEDLRNNLKFRQDLYYRLSV
                     IPVKIPPLRERKEDIVPLVNYFLKLYNEKYNREVEVSPKVIELLEEYSWPGNIRELKN
                     IIERFVVLSAKNVIGEDEFNMLINLDMIDNETDDLSPIVVNGIMNLNDAYKIVDQIMI
                     SKAINKYGSITKAAEVIGIYPSTIHRKIKSGHIHV"
     gene            complement(5000..6037)
                     /locus_tag="JAM15_14830"
     CDS             complement(5000..6037)
                     /locus_tag="JAM15_14830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HAT6799526.1"
                     /translation="MNDIKDLSSYKNVWIFAEQREGKIAPVVIELLGEGRKLAKEVDA
                     ELCAILLGKDVDGLAKELITFGADKVYVADDALLEKYTTDAYTKVIKDAIDEIKPEIM
                     LFGATHIGRDLAPRIASRVGTGLTADCTKLEIDPEDKKIKQTRPAFGGNIMATIICPN
                     HRPQMSTVRPGVMDKAEKDETRTGEVIALDYKITQDDIRTTVLETVKTKKDLVSLTDA
                     NVIVSGGLGLGGPEGFEMLKKLADKLGGVVGSSRAAVDAGWIDHSHQVGQTGTTVKPN
                     LYIACGISGAIQHLAGMQSSDFIIAINKNPAAPILEIADYGVVGDLHEIVPMLIEKLD
                     SVDDLLEAIKA"
     gene            complement(6056..6841)
                     /locus_tag="JAM15_14835"
     CDS             complement(6056..6841)
                     /locus_tag="JAM15_14835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005367473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HAT6799527.1"
                     /translation="MKILVCVKQVPDTNEVRINKETGTLIRDGVPSILNPDDANALEE
                     ALKIKDEHDDVTITVITMGPPQADFMLRECLAMGADDAILLSDRAFGGADTWATSNTI
                     AAGISKVGDYDIIFAGRQAIDGDTAQVGPQIAEKLDIPQVTYVQDFKIEGKDIIVQRQ
                     LEDGYELIKVSTPVLLTAVKELNTPRYMSVDKIVKAYKHDVKVWTIDDLDVNKEEVGL
                     KASPTKVFRSFTPEPRGKGEILEGKADEIASKIIIGLKQKHII"
     gene            complement(6874..8007)
                     /locus_tag="JAM15_14840"
     CDS             complement(6874..8007)
                     /locus_tag="JAM15_14840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009081804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HAT6799528.1"
                     /translation="MLYNKEQELLRKAVRDFVSKELDTLPAEMDKTGVMPKELIKKLA
                     DAKFISSNIPEEYGGGGAGYVSYAIVMEEIARRCASTATFVTAGSSLASLPILYNGTE
                     EQKQKYLKGIATGELIGAFGLTEPGAGSDAGGQQTTAELVGDHYILNGRKTFITNGPF
                     CDVAIVIAVTDRSKGLRGTSAFIVESKWDGFSTGAHEDKMGIRGTETSDLIFENVKVP
                     KENLLGKEGQGFKIAMGTLEVGRIGVAALALGIAQGALDEAVKYTKQRVQFGKPIAKF
                     QNTQFTIADMETKVCAARGLVYDAAQKRDAGMRVAQESAMAKYYASEIANEVAYKALQ
                     LHGGYGFIKDYEIERMYRDARIVSIYEGTSEVQKMVISSNVLK"
     gene            complement(8055..9182)
                     /gene="hadC"
                     /locus_tag="JAM15_14845"
     CDS             complement(8055..9182)
                     /gene="hadC"
                     /locus_tag="JAM15_14845"
                     /EC_number="4.2.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     beta"
                     /protein_id="HAT6799529.1"
                     /translation="MEAILSKMKEVVENPNAAVKKYKSETGKKAIGCFPVYCPEEIIH
                     AAGMLPVGIWGGQTELDLAKQYFPAFACSIMQSCLEYGLKGAYDELSGVIIPGMCDTL
                     ICLGQNWKSAVPHIKYISLVHPQNRKLEAGVKYLISEYKGVKRELEEICGYEIEEAKI
                     HESIEVYNEHRKTMRDFVEVAYKHSNTIKPSIRSLVIKSGFFMRKEEHTELVKDLIAK
                     LNAMPEEVCSGKKVLLTGILADSKDILDILEDNNISVVADDLAQETRQFRTDVPAGDD
                     ALERLARQWSNIEGCSLAYDPKKKRGSLIVDEVKKKDIDGVIFCMMKFCDPEEYDYPL
                     VRKDIEDSGIPTLYVEIDQQTQNNEQARTRIQTFAEMMSLA"
     gene            complement(9182..10408)
                     /gene="hadB"
                     /locus_tag="JAM15_14850"
     CDS             complement(9182..10408)
                     /gene="hadB"
                     /locus_tag="JAM15_14850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     HadB"
                     /protein_id="HAT6799530.1"
                     /translation="MSEKKEARVVINDLLAEQYANAFKAKEEGRPVGWSTSVFPQELA
                     EVFDLNVLYPENQAAGVAAKKGSLELCEIAESKGYSIDLCAYARTNFGLLENGGCEAL
                     DMPAPDFLLCCNNICNQVIKWYENISRELDIPLIMIDTTFNNEDEVTQSRIDYIKAQF
                     EEAIKQLEIISGKKFDPKKFEEVMKISAENGRLWKYSMSLPADSSPSPMNGFDLFTYM
                     AVIVCARGKKETTEAFKLLIEELEDNMKTGKSSFRGEEKYRIMMEGIPCWPYIGYKMK
                     TLAKFGVNMTGSVYPHAWALQYEVNDLDGMAVAYSTMFNNVNLDRMTKYRVDSLVEGK
                     CDGAFYHMNRSCKLMSLIQYEMQRRAAEETGLPYAGFDGDQADPRAFTNAQFETRIQG
                     LVEVMEERKKLNRGEI"
     gene            complement(10423..11223)
                     /gene="hadI"
                     /locus_tag="JAM15_14855"
     CDS             complement(10423..11223)
                     /gene="hadI"
                     /locus_tag="JAM15_14855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyisocaproyl-CoA dehydratase activator
                     HadI"
                     /protein_id="HAT6799531.1"
                     /translation="MYTMGLDIGSTASKGVILKNGEDIVASETISSGTGTTGPSRVLE
                     KLYGKTGLAREDIKKVVVTGYGRMNYSDADKQISELSCHARGVNFIIPETRTIIDIGG
                     QDAKVLKLDNNGRLLNFLMNDKCAAGTGRFLDVMAKIIEVDVSELGSISMNSQNEVSI
                     SSTCTVFAESEVISHLSENAKIEDIVAGIHTSVAKRVSSLVKRIGVQRNVVMVGGVAR
                     NSGIVRAMAREINTEIIVPDIPQLTGALGAALYAFDEAKESQKEVKNI"
     gene            complement(11262..12461)
                     /gene="hadA"
                     /locus_tag="JAM15_14860"
     CDS             complement(11262..12461)
                     /gene="hadA"
                     /locus_tag="JAM15_14860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocaprenoyl-CoA:2-hydroxyisocaproate
                     CoA-transferase HadA"
                     /protein_id="HAT6799532.1"
                     /translation="MLLEGVKVVELSSFIAAPCCAKMLGDWGAEVIKIEPIEGDGIRV
                     MGGTFKSPASDDENPMFELENGNKKGVSINVKSKEGVEILHKLLSEADIFVTNVRVQA
                     LEKMGIAYDQIKDKYPGLIFSQILGYGEKGPLKDKPGFDYTAYFARGGVSQSVMEKGT
                     SPANTAAGFGDHYAGLALAAGSLAALHKKAQTGKGERVTVSLFHTAIYGMGTMITTAQ
                     YGNEMPLSRENPNSPLMTTYKCKDGRWIQLALIQYNKWLGKFCKVINREYILEDDRYN
                     NIDSMVNHVEDLVKIVGEAMLEKTLDEWSALLEEADLPFEKIQSCEDLLDDEQAWAND
                     FLFKKTYDSGNTGVLVNTPVMFRNEGIKEYTPAPKVGQHTVEVLKSLGYDEEKINNFK
                     DSKVVRY"
     gene            13138..14136
                     /locus_tag="JAM15_14865"
     CDS             13138..14136
                     /locus_tag="JAM15_14865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-2-hydroxyacid dehydrogenase"
                     /protein_id="HAT6799533.1"
                     /translation="MKILVFGARDYEEPVIKKWSEEHKDVQVDIYPENMTEENVVKAK
                     GYDGISIQQTNYIDNPYIYETLKDAGVKVIASRTAGVDMIHFDLVNENGLIVTNVPSY
                     SPNAIAELAVTQAMNLLRKTPLVKKKVCEGDYRWIAELLGTEVRSITVGVIGTGKIGA
                     TSAKLFKGLGANVIAFDQYPNSDLNDILTYKDSLEDLLKEADLITLHTPLLEGTKHMI
                     NKDTLAIMKDGAYIVNTGRGGLINTGDLIEALESGKIRAAALDTFETEGLFLNKKMNP
                     GELTDPEINKLLSMEQVIFTHHLGFFTSTAIENIVYSSLSSAVEVIKTGTATNRVN"
     gene            14498..15025
                     /locus_tag="JAM15_14870"
     CDS             14498..15025
                     /locus_tag="JAM15_14870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04002 family protein"
                     /protein_id="HAT6799534.1"
                     /translation="MEKMNKVTSKKTTYIVTSALFASIICLTIAYILHIPVGGNNGYV
                     HIGDAFIYLAATILPTNYAIAASAIGAGLADLSTGAAIWVIPTIIIKPILVLFFTSKS
                     DKIINKRNIVASVVAGIVGLVLYMFAEGIIIGSFTSAFVMSLLGLLQPIGSFIVFIIL
                     GMALDKLDFKKRYFN"
     gene            15052..15648
                     /locus_tag="JAM15_14875"
     CDS             15052..15648
                     /locus_tag="JAM15_14875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04100 family radical SAM protein"
                     /protein_id="HAT6799535.1"
                     /translation="MNILYTIENSIYVNITNTCPCSCVFCIRNEKDEVANSGSLWLEH
                     EPSVDEVKEAFNKYNLDDYDEIVFCGYGEPLMRINELIEVAKFIKEKSSIKIRINTNG
                     LSDLIHNKKTAILLKDVIDAVSISLNAPNKEAYNRVTQPKFGEKSFDYMLDFARDCKK
                     YIKEVAFSVVDEISPEEIEESKQLAKKLDIPLRVRHKN"
     gene            complement(15713..17251)
                     /gene="asnB"
                     /locus_tag="JAM15_14880"
     CDS             complement(15713..17251)
                     /gene="asnB"
                     /locus_tag="JAM15_14880"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009003644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HAT6799536.1"
                     /translation="MIKILEYNGHIRNWKVLCEELGIDSSLCRDERERAILVEAYKTW
                     GYDMANHMHGMFAFALWDTVEKKLFCLRDQFGVKPFYYYETENGKLLYGSSIRKIMEQ
                     PGFVKELNEDMLQIYMSFTYVAGENTFFRGVKKLMPGHYLVYQNKTVCIGRYWKPEFH
                     PDHSKSIEEWTDEIHTTLQKIMPEVKSENETAELFLSGGVDSSYILAMSDIEKTGSCG
                     YEEDRFDESKLAQQTANILGCKNSRYIITPEEYFASVPYVMYHMEQPTGDASAIVFAI
                     GCKAAAENTNICYSGEGADEFFGGYNIYHKAECYGENLKTFYIGNTNIMNEGEKRKIL
                     KKYNPDVLPIEVVKGIYEETEELDTLTNMSNVDIQIWLEGDIYFNIDKMSTAVGLEVR
                     MPLTDTRIFDIASRIPSEYKVKGKENKIAFRTAASKTLPEEIAFRNKLGFIVPIRIWM
                     ADDQYNKDIRDKFNSEIADKFFNIDEINEIFNDYISGNSDNWRKIWMIYTFLVWYEIY
                     FVKC"
     gene            complement(17862..18698)
                     /locus_tag="JAM15_14885"
     CDS             complement(17862..18698)
                     /locus_tag="JAM15_14885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAT6799537.1"
                     /translation="MNYIIKKVLNSSVVLVHDAKYNEFILLGKGIGYGKKTGEYICGS
                     NDNQMFVPVENTKSKQFLELMDDIPVDILKITQEIIVEAEKLLNSSFNKNLYLILADH
                     FNFAIERMRKGIKITNRVFWEIKNYYPNEFKVGMVAIYMVEERLGIQLPEEEAANIAF
                     HFANAMASDGNSYDTIKYAKVIGEIINIFVFSLNRTLDKKSMHYMRFITHIKFFVERF
                     FSDSMLSSGDDLLFNQMKRSNPKEMLIALKVRDFLEKKYGKKLTNEEIAFLVVHIARV
                     KQ"
     gene            complement(18722..18877)
                     /locus_tag="JAM15_14890"
                     /pseudo
     CDS             complement(18722..18877)
                     /locus_tag="JAM15_14890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008690640.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
BASE COUNT         5875 a         3380 c         2338 g         7353 t
ORIGIN      
        1 tttttctgat tattaatata ttttcttatc tgttcttctg tattttctga tacagtagca
       61 acgaaataac taggattcca aagatgttct ccccataatt tctttttcaa ctgttctcca
      121 tgttttttca ttaacaacct tgtcgataca cattttaatg cttttatcat atctggtata
      181 tagtgttgtg gtgaacaatt tattagtaaa tgtatgtggt ctttgtcact attacattct
      241 aatatttgaa atttattatc tttagctatt ttgtttaata tattaattaa atcttcttca
      301 atttcatttg ttaatactgg atgtctatat tttacacacc atactatatg gtattatact
      361 aaatacacat accctctacc atgagtcact tccatttttc atcacctagc ataatattaa
      421 catagtaatt acttaaaaca agtattctta aggtttttat atttattttt aaataacata
      481 tgtaagaact ataagtctta acttttatca tttttgaggt tgtcgttcac ataagttcgc
      541 tactacctat gcagttctct tatgaacttc ttacactttc atgcaagcac agactatatc
      601 ttatccttcg gcattatccg ttaaggtcta cccacttcca ctaccgataa cttgtagtgt
      661 acttccctca agaggaatag tcgttgaagt ttctcctatt cggagtttac ctgctgattg
      721 cccattttaa agtacttagg gtttaacctt ataccatcta accaattttt tctactttcg
      781 taactttcac acttaggttt atttcatcct tatgttttag tttggttagc tttaggggtt
      841 tccagcaatt caagtagtat tggataggct ctatcctatc tctacatata agtttcccta
      901 tatgctgact attttagcta ctaactcatg actaaagtca cgagtgtacg tagctatttt
      961 ttaatcaaat atatatattc tctatatata atttcttctc cattaaataa tatctcatca
     1021 ttttcagtgt ctacttgagt tcctggattt gaaacttcac ttccatttac tactacagac
     1081 ccttgtttac aatacttctt tatttcactt ctacttccat aacctaaatt tgaaagaatt
     1141 ttatctatac gttgcttttt agccattaaa aatgctctcc attctcataa tatttttctt
     1201 tttcaaatac tgtaaatgct aaatccatac tttctacatc taaattattt cttatactat
     1261 cagttattat tcttgctact atatcttgta cttcttgtcc tctatcaaac caagctactt
     1321 caacaaaagg atatacatct gctattttac catctcttat tgcaactgac tttatacatt
     1381 ctatttcaaa gtagtctctt ggacatttta cagcttcaac taaatcattt atcatttttt
     1441 cacttatttt acatatatca ttttcattaa ttcctcttat ttttatctgt ggcatagttt
     1501 atctccttta ttttaaattt ttagtgaatt atcatccact taattccctt cgataacgtt
     1561 tgaagtggta acttcttggt caagacaact attgttatca gtatctccaa actaataagg
     1621 tagttcctac ccttatagtt agcattatat agctaatttt cctaaattgt ttatattctt
     1681 tattatttta tttaatccta ttgtcttcta tttaacatta tacttgtaat ttatagttat
     1741 tacaatttac tatatacttt ttttgattta acgttataat ataagtgatg ggtaaatttt
     1801 aaaagttaat aggaggagtt taaaatggca ttaattacta caaaagaaat gtttaaaaaa
     1861 gcttacgaag gtggatttgc tataggtgca tttaacataa gtgacttaga acaattacaa
     1921 ggtgttttaa aagctgctaa agctaaaaat tcttatgtta tgatacaagc ttctatgtca
     1981 gctgttaaat atgctggacc tcatacatta gttgaaatgg ttaaggctgc ttctgatgaa
     2041 ataggtgtag atgtagctct tcacttagac catggtccaa atatggatgc tattaaaact
     2101 tgtattgatg ctggtttctc ttcagttatg atagatggtt ctcattttga ctttgaagaa
     2161 aatgttagaa taactaaaga agctgttgaa tatgcacact ctaaaggtgt tgttgttgaa
     2221 gcagaacttg gtgttctagc tggaacagaa gatgatgtta cttctgatgt tcacaagtat
     2281 actcaaccag ctgaggcagt tgagttcgtt gaaagaacag gtgttgattc attagcaata
     2341 gctattggaa cttctcatgg tgctttcaaa ttcaaaggag aagctaaatt aagatttgat
     2401 atactagaag aaatccaaag caaattacca ggtttcccaa tagttcttca tggtgcatct
     2461 gctgttgacc aaaacgctgt tgctacatgt aatgaatttg gtggaaatat agctggtgct
     2521 aaaggtgtac ctgtagatat gttaagaaaa gcatcttcta tggctgtttg taaaataaac
     2581 atggatactg acttaagact agctatgact gctgctatca gaaaattctt agctgaaaat
     2641 ccaaaagaat ttgacccaag aaaatacatt ggtgctggta gagatgctat acaagctgta
     2701 gttgaaagca agatagatga tgttttaggt tctgctaact ctataaacta atataacttt
     2761 taaatattta taaaagaaaa gagatgactt aaagtaatta aatttatttt taagccatct
     2821 cttttaagtt gtatcaatta tgtatcttat aatattttaa ttatattgtc tttttaaact
     2881 gacagctaaa cgtgaatatg tccactcttt atctttctat ggatggtaga aggatatata
     2941 cctataactt cagcagcctt tgttattgaa ccatacttat ttatagcctt acttatcatt
     3001 atttggtcca ctattttata tgcatcatta agattcataa ttccatttac cactattggt
     3061 gataaatcat ctgtttcatt atcaatcata tctaaattta tcagcatgtt aaattcatct
     3121 tctccaatta catttttagc tgataatact acaaatcttt caatgatgtt ttttaattct
     3181 cttatgtttc ctggccaaga atattcttct aataactcaa taactttagg tgaaacttct
     3241 acttctctat tgtacttttc attgtaaagt tttaagaaat aatttactaa tggtactata
     3301 tcctcttttc tttctctaag aggaggtatt tttactggaa taacacttaa tctatagtac
     3361 aaatcttgtc taaatttaag gttatttcta aggtcttcat gagaaatatt agtagcactt
     3421 atatatctaa catctatttt tataggctta ctaccaccta ttctagtaat agtattttct
     3481 tgtataaccc taagtaattt tttttgcatc tgcattggta actcacctat ctcatccaag
     3541 aaaatagttc caccattcgc ctcttcaaaa agtccctttt tacctttttt cttagctcca
     3601 gtaaaagaac cttcttcata tccaaaaaac tctgactcta ataattcatt tggtatagct
     3661 ccacagttta tagctataaa aggtttgtct ctccttgaac tatacttata tattgttctt
     3721 gctattattt cttttcctac acctgattct ccatttataa atatagaaga atctgaggct
     3781 gcagctctct taacaacttt ttttatattg tccataatct tactttgact tatatactct
     3841 gtgtcttctg atatatcact atattttatc tgagattcaa gcttaataac ccttgaaata
     3901 tctctccctg ttagtactcc tcctgtaagc tttcccttag aatcccatct tggaactgcc
     3961 gtatatgcaa taagcttccc atctgggtaa acgatatttc tataaatctt tttcttcact
     4021 ttaagcatgt ttaatattat tggttcttca actaatcctt gtctcacaag gtctgttata
     4081 tttctaccaa gtacctcagt tcttttaaaa ggtaatatct catcactgac agtgttcatc
     4141 ttttcaatta ccccatcttt gttaaacaca acaacaactt catctatatg ctctattata
     4201 tcttcaatta ctttatcaga tattagagac ttctcaaata aataaactat attattttca
     4261 ttattattat ctttcatatt gtatatatgt gcagtcatcc ttaactctct gaaagctatt
     4321 ttctttttac tatctgtcag tatttctgtt ttgtcaaaat ttgaatctaa ttcatttata
     4381 tttctaggct tttttatatc tagaaaacta aaaatactat ctattagatg attacagtat
     4441 attatttcgc ctgattcttt acataaaatg gctggatttt ctacatgttc tataagccct
     4501 attaaattat tatccattaa tattcgcacc tttcattaag taatttattg aactacatac
     4561 aaaatttatt gtttgcttac aataaatacc atcagcacat ataatcaact ccttataata
     4621 ttcgtctttt caagtagttt atttcattaa aacgtaacta agatataatt ttaatgatta
     4681 tagtttgtta aaaatttcat tttgctttta attgtatttt atcacatatt tagtaattat
     4741 ttgtctattt aatacaattt aattaaattt aagatttatt taaaaaaaca aagataatcc
     4801 ttacagaata taactcacaa tttgtaagca atatacatat aaggattatc cagattatct
     4861 tgtattataa aattttattc aaacagactt tttaataact gacaaataca cactagcaat
     4921 aacttatcaa agggttaata attatgttac taactaataa gacttattca atcagtaata
     4981 tttatatagt ttgtatctat taagctttta tagcttctaa taaatcatca acgctatcta
     5041 atttttctat aagcattgga actatttcat gtaagtctcc aactactcca tagtcagcga
     5101 tttctaaaat tggagctgct gggtttttgt ttatagcaat tatgaaatct gatgattgca
     5161 tacctgctaa atgttgtatt gctcctgata taccacaagc tatatatagg tttggtttaa
     5221 cagtagttcc tgtttgacct acttggtgag aatggtctat ccatccagca tcaacagccg
     5281 cacgagaaga accaactact ccacctaatt tgtcagctaa tttcttaagc atttcaaatc
     5341 cttctggtcc acctaatcct aaaccacctg atactataac atttgcatct gtaagagata
     5401 ctaaatcttt cttagtttta actgtttcta aaacagtagt tcttatatca tcttgagtta
     5461 ttttgtagtc taatgctata acttcaccag ttcttgtttc gtctttttca gctttatcca
     5521 taacaccagg tctaactgta gacatttgag gtctatggtt tggacaaatg attgtagcca
     5581 ttatgtttcc accaaatgct ggacgagttt gttttatttt cttatcttct gggtctattt
     5641 ctaacttagt acagtcagct gttaatccag ttccaactct tgaagctatt ctaggtgcta
     5701 agtctctacc tatatgagtt gctccgaaaa gcattatttc tggttttatt tcatctattg
     5761 catcttttat tacttttgta tatgcatcag ttgtatattt ttctaaaaga gcatcatctg
     5821 caacataaac tttgtcagct ccaaaagtga ttaattcttt agctaatcca tcaacatctt
     5881 ttcctaataa tattgcacaa agttctgcat ctacttcttt agctaatttt cttccttctc
     5941 ctaataattc tataactact ggagctattt ttccttctct ttgttctgca aatatccata
     6001 cgtttttata agaacttaaa tcttttatat cattcatagt ttgtactcct ccaacttata
     6061 taatgtgctt ttgttttaga ccgattatta ttttactagc tatttcatca gctttacctt
     6121 ctaagatttc tccttttcct cttggttcag gagtaaatga tctaaatact ttagttggtg
     6181 atgcttttaa accaacttct tctttattta catctaaatc atcaattgtc caaactttta
     6241 catcatgttt atatgctttt actattttat caacagacat gtatctaggt gtatttaact
     6301 cttttactgc tgttaaaagt acaggtgtac ttacttttat taattcgtat ccatcttcta
     6361 attgtctttg aactattata tcttttcctt ctattttgaa atcttgtaca tatgtaactt
     6421 gaggaatgtc taatttctct gcaatttgtg gtccaacttg tgcagtatct ccatctattg
     6481 cttgtcttcc tgcaaatatt atgtcatagt cacctacttt agatattccc gctgcaatag
     6541 tatttgatgt agcccaagta tcagctcctc caaatgctct atcacttaat aatattgcat
     6601 catcagcacc catagctaaa cactctctta gcataaagtc tgcttgagga ggtcccattg
     6661 ttataactgt tatagttaca tcatcatgct catctttaat ttttaaagct tcctctaatg
     6721 catttgcatc atctgggttt aatatacttg gaactccatc tcttataaga gtacctgttt
     6781 ctttatttat tcttacttcg ttagtatctg gaacttgttt tacgcaaact aatattttca
     6841 aagtctatac ctccaatttc attagattat ttattatttt aatacgtttg atgaaattac
     6901 cattttttga acttctgatg ttccttcgta tattgatacg attctagcat ctctgtacat
     6961 tctttcgatt tcataatctt ttataaatcc atatccaccg tgaagttgta atgctttata
     7021 agcaacttca tttgcaattt ctgatgcata gtatttagcc atagcagatt cttgagcaac
     7081 tctcattcct gcatctctct tttgtgctgc atcataaact aatcctctag ctgcacaaac
     7141 ttttgtttcc atgtcagcta tagtaaattg agtattttgg aatttagcta taggcttacc
     7201 aaattgaact ctttgttttg tatatttaac agcttcatct aaagcgcctt gagctattcc
     7261 tagagctaag gcagcaacac ctattctacc aacttctaga gtacccattg ctatcttaaa
     7321 tccttgacct tcttttccaa gtaagttttc ttttggaact ttaacgtttt caaatattaa
     7381 gtcagaagtt tcagttcctc ttatacccat cttatcttca tgagctcctg ttgagaaacc
     7441 atcccattta ctttctacta taaacgctga tgttcctcta agtcctttac ttctatctgt
     7501 aactgctatt actatagcta catcacagaa tggtccatta gttatgaaag tttttctacc
     7561 atttaatata tagtggtctc caactaattc tgctgttgtt tgttgtccac ctgcatcaga
     7621 accagctcct ggctcagtta acccaaatgc tcctattaat tcacctgttg ctataccttt
     7681 taagtatttt tgtttttgct cttcagtacc attgtaaagt attggtaatg aagcaagaga
     7741 agaaccagct gtaacaaaag tagctgttga agcacatctt ctagctattt cttccattac
     7801 tatagcgtaa gaaacatatc ctgctccccc accaccatat tcttctggga tattactgct
     7861 tataaatttt gcatcagcta attttttgat taattcctta ggcattacac ctgttttatc
     7921 catttctgct ggtaaagtat ctaattcttt actaacaaaa tctcttactg cttttcttaa
     7981 aagttcttgt tctttgttat ataacatagc ttcctccaat tttcatattt tatagtaaat
     8041 ttattttaat gaacttacgc taaactcatc atctcagcaa aagtttgaat acgagttctg
     8101 gcttgttcat tattctgagt ttgttggtcg atttcaacat ataaagtagg tattccacta
     8161 tcttctatat cttttctaac taaaggataa tcgtattctt ctgggtcaca gaatttcatc
     8221 atacagaaga taacaccatc tatatctttc tttttaactt catctactat aagtgaccca
     8281 cgttttttct tagggtcata agctaatgaa catccttcta tgtttgacca ttgtcttgct
     8341 aatctctcta acgcatcatc acctgctggt acatctgttc tgaattgtct tgtttcttgt
     8401 gctaagtcgt cagctacaac tgatatattg ttgtcttcta aaatgtctaa tatatcttta
     8461 gaatcagcta atatacctgt taataaaact ttttttccag aacagacttc ttctggcata
     8521 gcatttaatt ttgctattaa atctttcact agctcagtat gttcttcttt tctcataaag
     8581 aacccactct taattactaa gcttcttatt gatggtttta tagtattaga atgtttataa
     8641 gctacttcaa caaagtctct catagttttt ctatgttcat tgtaaacttc tatactttca
     8701 tgaatttttg cttcttctat ttcatatcca caaatttctt caagttctct ttttacacct
     8761 ttgtactcac tgattaagta ttttacacca gcttcaagtt ttctattttg tgggtgtact
     8821 aatgatatat attttatatg aggtactgct gatttccagt tttgtcctaa acaaattagt
     8881 gtatcacaca tacctggtat aataactcca gataattcat cataagcacc ttttaatcca
     8941 tattctaaac atgattgcat tattgaacat gcaaatgcag ggaaatattg tttagctaaa
     9001 tctaattctg tttgtcctcc ccatatacca actggaagca ttccagctgc atgtataatt
     9061 tcttctgggc aataaactgg gaaacaacct atagcttttt taccagtttc acttttatat
     9121 ttttttacag ccgcatttgg attttcaact acttctttca ttttagataa aatagcttcc
     9181 attatatctc acctctatta agtttttttc tttcttccat tacttcaact aaaccttgaa
     9241 ttcttgtttc aaattgagca ttagtgaaag ctctagggtc tgcttggtca ccatcaaatc
     9301 cagcatatgg taatccagtt tcttcagctg ctcttctttg catttcatat tgtattaaac
     9361 tcataagttt acagcttctg ttcatatgat agaatgctcc atcacattta ccctctacta
     9421 aagaatcaac tctatatttt gtcatacggt ctaggtttac attgttaaac atagtactat
     9481 atgctactgc cattccatct aaatcattaa cttcatattg taacgcccaa gcatgtgggt
     9541 aaacactacc tgtcatgtta actccaaatt tagctaatgt tttcatcttg tatcctatat
     9601 atggccaaca aggtatacct tccatcatta ttctgtattt ttcttcccct ctgaaagaag
     9661 atttaccagt tttcatgttg tcctctaatt cttctataag taacttaaat gcttctgtag
     9721 tttctttttt acctctagca caaactatta cagccatgta agtaaataag tcaaatccat
     9781 tcattggaga aggagaagaa tctgctggta aactcataga atacttccat agtcttccgt
     9841 tttcagctga tattttcatt acttcttcaa acttcttagg gtcaaatttc tttcctgata
     9901 taatttctag ttgttttata gcttcttcaa attgagcttt aatataatct attcttgatt
     9961 gagtaacttc gtcttcatta ttgaaagttg tatcaatcat tattaaaggt atatctaatt
    10021 ctcttgaaat attttcatac cattttataa cttggttaca tatattgtta cagcaaagta
    10081 ggaaatctgg agctggcata tccaaagctt cacatccacc attttctaaa agaccaaaat
    10141 ttgttcttgc atatgcacat aggtcaatag aatatccttt agattcagct atttcacata
    10201 attctaaaga acctttttta gctgctactc cagctgcttg gttttctgga tataatacgt
    10261 ttaagtcaaa tacttctgct aactcttgag gaaatactga tgttgaccaa cctacaggtc
    10321 ttccttcttc tttagcttta aatgcatttg catattgttc agctaataaa tcattaatta
    10381 ctactctagc ttcttttttt tcagacattt tcatccctct ttttatatat ttttcacttc
    10441 tttttgtgat tcttttgctt catcaaaagc atataacgct gctcctaaag caccagttaa
    10501 ttgaggtata tcaggtacaa taatttctgt gttgatttct cttgccatag ctcttacaat
    10561 accactattt ctagcaactc caccaaccat aactacattt ctttgtactc ctattctttt
    10621 tactaggcta gaaactctct ttgctactga agtatgaata cctgccacta tatcttcaat
    10681 ttttgcattt tcagataaat gtgatataac ctcagactct gcaaatactg tacatgtact
    10741 gcttattgat acttcatttt gagaattcat agatatactt ccgagttcag atacatcaac
    10801 ctctattatt tttgccatta catctaaaaa tcttcctgta cctgcagcgc atttgtcatt
    10861 cataagaaag tttaatagtc ttccattatt atctaatttt aatacctttg catcttgacc
    10921 gcctatgtca ataatggttc ttgtctctgg aattatgaaa tttacccctc tagcatgaca
    10981 gcttaattca cttatttgct tatcagcatc tgaatagttc attcttccat atcctgtaac
    11041 tacaactttt ttaatatctt ctcttgcaag acctgtcttg ccatataatt tttctaaaac
    11101 tcttgatggt ccagtagtcc cagtaccaga ggatattgtt tcagaagcta caatatcttc
    11161 cccattcttt aagattactc cctttgatgc agttgaacct atatctaatc ccattgtgta
    11221 catctttagc attctccttt taaaaaatct agaattacta attaatatct tacaacttta
    11281 ctatctttaa agttatttat tttctcttca tcgtagccta aagattttaa tacttctaca
    11341 gtatgttgac ctacttttgg tgctggtgta tattctttaa ttccttcatt tctaaacata
    11401 actggagtat taactaagac acctgtattt ccgctatcgt atgttttctt aaataagaag
    11461 tcatttgccc aagcttgttc gtcatctaat aaatcttcac agctttgaat tttttcaaat
    11521 ggtaagtctg cttcttctaa taaagctgac cactcgtcta atgttttttc taacatagct
    11581 tctccaacta tcttaactaa atcttcaaca tgattaacca ttgaatctat gttattatat
    11641 ctatcatctt ctaatatata ttctctattt ataaccttac agaatttgcc taaccacttg
    11701 ttgtattgta ttaaagctaa ttgaatccat cttccatctt tacatttata tgtagtcatt
    11761 aatgggctgt ttggattttc tcttgataaa ggcatttcat ttccgtattg tgctgttgtt
    11821 atcattgttc ccattccata tatagctgta tggaaaagac ttactgttac tctctcacct
    11881 ttaccagttt gagctttttt atgtaatgct gctaaacttc ctgctgctag tgctagacct
    11941 gcatagtggt caccaaatcc tgctgctgta tttgctggag atgttccttt ttccataaca
    12001 gattggctaa ctcctcctct tgcgaagtat gcagtatagt caaatcctgg tttatctttt
    12061 aaaggtcctt tttcaccata tcctaatatt tgagagaata ttaatcctgg atacttatct
    12121 tttatttggt cataagctat acccattttt tctaatgctt gaactctaac attagttaca
    12181 aatatgtctg cttctgataa taatttatgt aatatttcta ctccttcttt tgattttaca
    12241 ttaatactta cacccttttt atttccattt tctaattcaa acatagggtt ttcatcatct
    12301 gatgctggag atttaaatgt tccacccata actcttattc catcaccttc tataggttca
    12361 atcttaataa cctctgcacc ccagtcacct aacatttttg cacaacatgg tgctgcgatg
    12421 aaacttgaaa gttctactac tttaactcct tctaaaagca taacgttttc ctccttaata
    12481 gtatcaatta taaaatttcg attaaatcac tcataaaata cttttttctg atattaactg
    12541 tctgatgtca aagttcctaa tcttatctaa aataacttaa aaattattaa aattattttt
    12601 tattgtttta ttgtcttaca cctatattgt taagcattta tcgtgccaac tttatattta
    12661 atcaaaatat cgcttgattt gaatgttttt taacaatatg caattgaata atctttttca
    12721 tatcgtggca tcttgccact atccattgca ttttgctatt ctttctatgc ttataaaagt
    12781 tttttttata tattttttta tgaaaaagct tgacatttca aaaaaagttt tcattgctaa
    12841 actcaaaaac acatgttatc attgtaatta atcagcaagt tagttaacta atttcaaact
    12901 tagataattt tttaataata tttaatctaa aaaataacaa tttctttgat aaattttaga
    12961 gtaattatta cattaaataa aaaattacta aatatcaaaa taacacaggg aaaacaattt
    13021 caaaactaaa tttttaacct taaaaatttt gtataaaaaa tataacctta tatgctacat
    13081 attatttcta aatgaaaaat taccataata atttaataat tacaggaggg tattgatatg
    13141 aaaatactag tatttggagc acgcgattat gaagaaccag taataaaaaa atggtctgaa
    13201 gaacataagg atgttcaagt ggatatttat cctgaaaaca tgactgaaga aaatgtagtt
    13261 aaagctaaag ggtatgatgg tatatctata caacaaacta actatataga taatccttat
    13321 atttatgaaa ctttaaaaga tgctggggtt aaagttatag cttcaagaac tgcaggggtt
    13381 gacatgatac attttgattt agttaatgaa aatggactta tcgttacaaa cgttccttct
    13441 tattcaccta atgcaatagc tgaattagct gttactcaag ctatgaacct tttaagaaag
    13501 actcctctag taaagaaaaa agtctgtgaa ggtgattacc gttggatagc tgaacttctt
    13561 ggaacagaag ttagatctat tacagttggt gttataggta caggaaaaat aggtgctact
    13621 tctgcaaaat tattcaaagg cctaggagct aatgtaattg catttgacca atatccaaat
    13681 agtgatttaa acgatatatt aacttacaaa gattctttag aagaccttct aaaagaagct
    13741 gaccttataa cattacatac tcctttactt gaaggaacaa aacatatgat aaataaagat
    13801 actctagcta taatgaagga tggagcttac atagtaaata ctggtcgtgg tggtttaatt
    13861 aatacagggg atttaataga agcactagag tcaggaaaaa ttagagctgc tgcccttgat
    13921 acatttgaaa ctgaaggatt gttcttaaac aaaaaaatga atcctggaga attaactgac
    13981 ccagaaataa ataaacttct ttctatggaa caagttatat tcactcatca ccttggtttc
    14041 ttcactagta cagcgattga aaatatagtt tattctagtt taagtagtgc tgtagaagtt
    14101 ataaaaacag gaactgctac taatagagta aattagtatt ttataaatat attttttcat
    14161 taattagcta ttatctaaca aaatagcctt taatttccca aatataagag agtcagctca
    14221 gtatatattg agtagactct cttatattat tttttatatt aaacttgtac tcctcttatt
    14281 catatcaaat taaatttata ttaacttact ctaactactc ctactctata cattttacct
    14341 atttttactt ttctaattat atacatttga atgggtacaa tctgtatttt acaaaaaaaa
    14401 cacctaacaa actatgaaaa ttgtatgatt aatattaata tatttataag aaaacataac
    14461 aattatgtta gctctggatt tttagggagg gagtatattg gaaaaaatga ataaagttac
    14521 ttctaaaaaa actacctata ttgttacttc agcattattt gcatccataa tatgcctgac
    14581 aatagcatat atattacata ttccagttgg tggaaacaat ggatatgttc atataggaga
    14641 tgcttttatt tatctagctg caactatttt gccaacaaac tatgctatag ctgcttctgc
    14701 aattggtgct ggtctagctg atttatctac aggtgctgct atctgggtaa taccaactat
    14761 aatcataaaa ccaatacttg tattattttt cacttctaaa agtgacaaga taataaataa
    14821 gagaaatata gttgcttcag ttgtagcagg tatagtagga ttagttttat acatgtttgc
    14881 tgaaggtata attattggaa gttttacaag tgcatttgta atgagcttac ttggcttatt
    14941 acagccaata ggaagtttta ttgtttttat aatcttaggt atggcacttg ataaacttga
    15001 ttttaaaaaa cgttatttta attaagaatt taaatttatg gagggaaaat tatgaatatc
    15061 ttatatacaa ttgaaaatag tatctatgta aatataacta atacatgtcc atgtagttgt
    15121 gttttttgta taagaaacga aaaagatgaa gttgcaaata gtggtagttt atggttggag
    15181 catgagccaa gtgtagatga agtaaaagaa gccttcaata aatacaattt agacgactat
    15241 gatgaaatcg tattttgtgg atatggcgaa ccattaatga gaataaatga attgatagag
    15301 gtagcaaagt ttataaaaga aaaaagtagc ataaaaataa gaataaatac aaatggtcta
    15361 agtgatttaa tacataacaa aaaaacagct attctgttaa aagatgttat agatgcagta
    15421 tcaataagtc ttaatgcccc aaataaagaa gcttataata gagttactca accaaagttt
    15481 ggagaaaaat catttgacta tatgttagat tttgcaagag attgcaaaaa atatataaaa
    15541 gaagtagctt tttcagtagt agatgaaata tctccagaag aaatagaaga atctaaacaa
    15601 ctggcaaaaa aacttgatat accattaaga gttagacata agaattagca agtaaaatta
    15661 taaaacatta agaatcacct gaatggtctt tcaggtgatt cttcctcttg tattaacatt
    15721 ttacaaaata gatttcatac cacactagga atgtgtaaat catccaaatc tttctccaat
    15781 tatcagagtt tccactaatg tagtcattaa aaatctcatt aatctcatct atgttaaaga
    15841 atttatctgc tatctcacta ttgaatttat ctcggatatc cttattatat tggtcatcag
    15901 ccatccatat acgaattggc acaataaatc ctaatttatt tctaaaagca atctcttctg
    15961 gtaatgtttt tgatgcagct gtacgaaagg caattttatt ctcttttcct ttcactttat
    16021 attctgatgg tattctggat gcaatatcaa atattcttgt atctgtaaga ggcattctga
    16081 cttccaatcc aactgcagta ctcattttat ctatattaaa ataaatatct ccttccaacc
    16141 atatttgaat atctacattt gacatgttag taagtgtatc tagttcttct gtttcttcat
    16201 aaattccttt taccacttca ataggaagca catcaggatt gtatttctta agaatttttc
    16261 ttttctcacc ctcattcata atgtttgtat ttccaatata aaatgtcttc aaattctctc
    16321 cataacactc tgccttatgg tatatattat atccaccaaa aaactcatct gctccttctc
    16381 cagagtaaca gatatttgtg ttttcagctg ctgccttgca tccaatagca aaaacgatag
    16441 cagatgcatc tccagttggt tgctccatat ggtacattac ataaggtact gacgcaaaat
    16501 actcttcagg tgtaattata tatctcgaat ttttacaccc aagaatatta gctgtctgtt
    16561 gtgctaattt tgattcatca aaacgatctt cctcataacc acatgaacct gttttttcta
    16621 tatctgacat tgccaatata taagatgaat caacacctcc tgataggaat aactctgcag
    16681 tttcattctc tgattttacc tctggcataa ttttctgaag tgttgtatga atttcatccg
    16741 tccattcctc aatagacttg ctgtggtcag gatgaaattc aggtttccaa taacgaccaa
    16801 tacatactgt tttattctga tagacaaggt aatgtcctgg cataagcttc tttactccac
    16861 ggaagaatgt attttcacct gctacatatg tgaaagacat ataaatctgt aacatgtctt
    16921 catttaactc tttcacaaat cctggttgct ccataatctt acgaatagat gaaccataga
    16981 gaagcttccc attttcagtc tcataataat agaaaggttt tactccaaac tggtctctta
    17041 ggcagaagag tttcttttcc acagtatccc ataatgcaaa ggcaaacatt ccatgcatgt
    17101 gatttgccat atcatatccc catgtcttat atgcttccac taaaattgct cgttcacgct
    17161 catctctaca taatgaagaa tcgattccaa gttcttcaca gagaactttc cagtttcgaa
    17221 tatgtccatt gtattctaga atttttatca tatatgtgtc ttttcgtgtt aaatactttt
    17281 cttctaaatt tatcatatgt gtatcctttc gtattaaaac atttaacttc taaatttatt
    17341 aaatgtttat atatatttat tcacttataa tcactgaaaa atcgactttt ttcaaagtaa
    17401 attatttttg aattagtact aatctgctct ttattaatgg cataaatatg attatcaagt
    17461 attatcagtg ttataacatt gaatttttta ttcttcataa atattgcccc ctttatatta
    17521 ccaactaaat ataatatatc ttatgttact tacatattct ttaagaaatt ctgaagattt
    17581 tataaagttt tctatattat aattaattaa aaataaaatt ctagttataa aacatatttt
    17641 ccattaaaca aaaaaatagt taaaataaat tcataaccac ataaacttat tttaactatt
    17701 tgtatatttt aattataaat attaacttaa atttttaaca ggatacactc ataaaataaa
    17761 cataatgaac aacaaaataa tatgtctcag tttctttata tactttacct tctttcaatt
    17821 ttctaccatg tagacgtata agataatatt agtaattcac tctattgctt aactcgtgcg
    17881 atatggacaa ccaagaaagc tatttcctca tttgttaact tttttccata tttcttttct
    17941 aaaaaatctc taacttttaa tgcaattaac atttcttttg gatttgacct tttcatttga
    18001 ttaaataata aatcatcacc actgcttaac atactatctg aaaaaaatct ttccacaaaa
    18061 aattttatat gtgttataaa tctcatataa tgcatactct ttttatctaa ggttctattc
    18121 aaagaaaaaa caaaaatatt aattatttct ccaattactt tggcatactt aatcgtatca
    18181 tatgaatttc catctgaagc catagcattt gcaaaatgga aagcaatgtt agctgcttct
    18241 tcctctggta attgaatgcc caatctctcc tctaccatat aaattgccac cattccaacc
    18301 ttaaactcat ttggataata attttttatt tcccaaaata ctcgatttgt aatttttatt
    18361 cctttacgca tcctttcaat tgcaaagtta aaatggtctg ctaatattaa gtataagttt
    18421 ttattaaaag atgagttcaa taacttttct gcctctacta ttatttcctg tgttatcttt
    18481 aaaatgtcga caggaatatc atccattaat tctaaaaatt gttttgattt tgtattttca
    18541 acagggacaa acatttgatt atcattggaa ccacaaatat attctcctgt ttttttacca
    18601 tatccaattc ctttccctag caaaataaat tcattatact ttgcatcatg aactaaaaca
    18661 acgctcgagt tcaaaacttt ctttattatg tagttcattt tatttgctca ccttctattg
    18721 gtcatttaaa atctatacta ttattttcaa ttaccttttt ataccaataa aaactatctt
    18781 tcttatatcg attatatgtc ccctttccat aatcatcagc atccacataa atatatccat
    18841 aacgttttga catttgtttc gttgattcac ttaccaactg aacctcccat gactaaagtc
    18901 acagggttcc tgcttcatag aattttgcat actaaaatat gtctta
//
LOCUS       DACTZW010000081        18846 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.081, whole genome shotgun sequence.
ACCESSION   DACTZW010000081 DACTZW010000000
VERSION     DACTZW010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18846)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18846)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18846
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.081"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            557..1987
                     /locus_tag="JAM15_14895"
     CDS             557..1987
                     /locus_tag="JAM15_14895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAT6799538.1"
                     /translation="MSSQESKPKGNLISNFRDDMRDPKKRAIYTYSSSINLAYNFIGY
                     FVSTVTNIFLTDVAKLGVIMAGGMQIIQSFIKIAVAPITGTVFDKQPFKKGKYYPWLR
                     YAPAALALTYGIFFIVPLMKISPALLLPLMTALLLIASCAQQVVFTIIYAIYPVVAKT
                     PRDRVIGSTTTNIFKEVGKFLVGFSYPLLLVLFADVLGGEGMGYLGTYLFFAAGCLLV
                     FWFSSTEIIKSGAEEEVLQKEEKPKIKASEMAKALFTNVPLMMAFCLEFLICIRSIGL
                     GPLAPYYFKYVIEDERGLAVFLSIMPLVSVAFMFFAPVFIKICREQKLASIISFSICA
                     LCHLLVAWTPWGKTTLGVTMLLAIGGGFSNVVSIINLNFFAGSCDYGHWKSGKDLPGL
                     SMSLYPVAIQVGVLLATTIRTVLMNSMGYQADMVVTEAVKSGFINMISYSMAIPLIIA
                     VVIAILYPVSDKKLNQIREELNQRNA"
     gene            2090..3193
                     /locus_tag="JAM15_14900"
     CDS             2090..3193
                     /locus_tag="JAM15_14900"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HAT6799539.1"
                     /translation="MIEKLLRNTVKELHQYVPGEPIEKVKEKYGVKEIIKLASNENPL
                     GPSPKAIEAMIEMLKQGQLYPEPEANELRRKLAEKLDLKPENFIVANGADNVITLIGE
                     AFINRGDEVIYCNPTFPSYRTATIKNEGIPVEVPLTEDYKYDLQGILDKITDKTKLIC
                     VCNPNNPTGTIVDDKELEEFLKKVPENIITILDEAYIEFLTVPNYVDGLKYVRENYNV
                     IVTRTFSKIYGLAGLRVGYGIAKDEIIRTLFTVKEPFSANRVAISGATAALDDEEFIK
                     ETYELNRVGMAYFKEEFTKMGFDVVDSQSNFLYVDMKTDIPKLFEDLKKRGFVIRPSA
                     THARVSIGTMEENKKFVAVLKEILNIKGEPSIG"
     gene            3208..3444
                     /locus_tag="JAM15_14905"
     CDS             3208..3444
                     /locus_tag="JAM15_14905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HAT6799540.1"
                     /translation="MKRGVDMNLKINAERCKSCEYCVISCKKGALKISSKINKEGYAH
                     VEVDESKCILCGICYQVCPDNVFEIIKEKACQEA"
     gene            3461..4510
                     /gene="vorB"
                     /locus_tag="JAM15_14910"
     CDS             3461..4510
                     /gene="vorB"
                     /locus_tag="JAM15_14910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HAT6799541.1"
                     /translation="MKKMWKGNHAIAEAALRGGCEFYAGYPITPQTEVMEFLSHRMSE
                     LGRTFIQSENEMAAIYMVYGAYASGMRSMTSSSGPGISLKQEGISYLCANHYPCVIVN
                     VQRWGPGLGSLDSAQTDYLRDTRGGGNGDYHLIVYAPNSIQETVDLMYNSFDVAEKYR
                     VPVEILTEAALGQMMEPVEFPEFKKREGDLGWTYDGSNRDHAKVADNQKPTFCMEKRM
                     RITENEQQWEDYQVEDAEYVFVAFGIPSRTTMNAVRRLREQGEKVGIIRPITVWPFPY
                     KAFEKVSKDVKGFISVESTDTGQLVEDVALASKKVCKENVPVYGLFSGNHIPKTLQVM
                     DTYSKIKSGEIKEVF"
     gene            4512..5252
                     /locus_tag="JAM15_14915"
     CDS             4512..5252
                     /locus_tag="JAM15_14915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HAT6799542.1"
                     /translation="MATEKLTPSVVSIPNKFCPGCGHGIVNRIIAEVIEEHGYEKNHV
                     LTLGVGCVCNMNFSWNGDKMQTAHGRASSTAIGVKVALPDTLVMTYQGDGDAYVIGLS
                     ETLNTAYRNHNVTVFVINNNNFAMTGGQMSWTTMPGQVTTTSVNGRDIKTTGSPLKVP
                     EMVANFFDVAYVARGSVHSPKEIINLKKYIKNAIEAQLNGEGYSLVEILAPCPTNWGV
                     SLEKSIKWMEEEIVPYYALGEFKQRDGE"
     gene            5255..5794
                     /locus_tag="JAM15_14920"
     CDS             5255..5794
                     /locus_tag="JAM15_14920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HAT6799543.1"
                     /translation="MEKELVFAGFGGQGVLTLGLIVAESALELGKQVTWMPAYGPTMR
                     GGKAYSVVKFSDESIGGPDMEEIDVLVAMNKPSLDYINLVKEGGTVVINTSAIDENVT
                     LREDISVVKINCQELAQKVNNPKAANIVVLGALIAKTGLFEKELALKTMCDFFEEKGK
                     GKFNVQNEAAFMEGYNNAI"
     gene            5918..8017
                     /locus_tag="JAM15_14925"
     CDS             5918..8017
                     /locus_tag="JAM15_14925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase family protein"
                     /protein_id="HAT6799544.1"
                     /translation="MSLEKLIRPKSIAIVGVTDKLGFGRSAALSIVKSKETDRVYYVN
                     PKREELFGRKCYKTIQEVPEVVDCVVVCTPRNVVPSVLKDSGELGTKAAVVYASGFAE
                     EGTEEGTDLENQLIEISNTYDMKILGPNCMGLLNCIDKVNLWAGGSKWDLDTKKPGIG
                     IVGQSGFITAEIVSSDYFNISYGFSTGNGNIVTLEDAVDFLVDDNYASVIAIYLEGLK
                     NPQKFIDVLKRAAQKRKPVIILKSGRSEKGAISAASHTGNLAGSSKAFESIFEKYGVI
                     SVENLEQFMCLAQAFSVLDGNLPANSNFAAINFSGGENTICADLAEENGVELAEISSE
                     TKEEMKKYLPGFATPKNPLDATTALFHEKDMIVGLLHTFEKDDSVGFTMVGANIRDEE
                     NEMHETLCKAVSEAREQGLKKPVFAVPTLEGNRYLDYRTRLEDNQVPIMSSVGTTFTC
                     FNKMAKFIDYDYSKRTLEFKAVKKRESNNVVALSELDSKIEMKKYGVPVPGQGNAKSI
                     DELDEILKYIKYPVVLKINSSEILHKSDVGGVKIGIKNRDEAVDAYNEILTNVKKAKP
                     DANIDGILVQEMVESGIEIIIGITNDDQFGPMLLVGLGGVFVEVFKDTTLYPLPINHD
                     EAIMMLKKLKSFKLLNGYRGSEPCDIDALADMMVKLGKYAYENKDEVKEIDLNPVFVY
                     PKGKGVCAVDALIVKYK"
     gene            complement(8284..8799)
                     /locus_tag="JAM15_14930"
     CDS             complement(8284..8799)
                     /locus_tag="JAM15_14930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin"
                     /protein_id="HAT6799545.1"
                     /translation="MISAKIEKLLNEQINHELYSAYLYLSMSSYLEAEGLKGFSNWFY
                     VQYKEETDHAMFFYKYLHNVGGKVQLDSIPMPDSDFTSAMDILERTLAHEKKVTALIN
                     NLAAVANSESDFRTSQFLLWFISEQAEEETNCEDNIKRVKLAGEGGLFFVDQEFANRT
                     YAAPTNPPVTI"
     gene            complement(8891..10102)
                     /locus_tag="JAM15_14935"
     CDS             complement(8891..10102)
                     /locus_tag="JAM15_14935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HAT6799546.1"
                     /translation="MSNKQGSNIKDVKIKNKLIILKLLSTNTPMSRVDLAKSTGLTKM
                     TLSNLVTELINENMIREIESSTLNAHSSGRKPILLDISNISPCICGILIRRNICKVII
                     SDLKGNIVKQLSETYPKCLSNDVLKDIIKRMFTKIMKINKRDIIGIGISSIGPVDDIN
                     GTILNPPDFGNVSNLNIVDFIKEMSDFPIFLINDANSGALAEKMYGLGKNISNYIYLH
                     IMNGIGAGLVLENKLHTGNLGQSGEIGHTSINFSGPLCSCGNNGCLDYYTSVSNLIKR
                     IESLSHIYPNSPLINCKDFSLVKLIDEANNKDSLAMFLLDEFCTYVSYALVNTLTLID
                     CSSIIIGYDFNIPGTFIENTLLKKLTASASFSRYKKISVRHSNFGANAPLIGSIAIVS
                     YNFFNGSINFY"
     gene            10778..12220
                     /locus_tag="JAM15_14940"
     CDS             10778..12220
                     /locus_tag="JAM15_14940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HAT6799547.1"
                     /translation="MRTIRRVLALGLTLAIFLINVPNVDALTSDTIKGNNIYETAGLI
                     ADKKSYDTAIMVNMDNSIADGLSASGLAGAVDAPILLAQKNKIPNETKQRLKNVKKIY
                     IIGKELSISKSVETELKNTGAQVTRLGGDDRIKTSYSVAKEVNGIKKVDEVILTNAYK
                     GEADTISAAPVSVRDIAPIVLTDGKSVPFSTSNVKTYAVGGSISMSTSLVNKTNAKRL
                     GGSDRYDTNKKVIKEFYPDASEFYLSDGYDLVNALTGSTIAKENPIVLVSESSDKSIL
                     AGADKITRLGSISDSVYNKCVSAAQNNGDSSTKGESPMKNETSILGQPTASLEACLKW
                     AKSKKANDLFIELIPILYDTAVQEGVNPVLAVAQSAKETGFCNFGGVLDASFKNPCGL
                     KTSVGGSDTDKNAHSRFDTWEEGILAQIQHLCLYAGQDGYPLSNPVDPRHEKSLFGKA
                     KTVESLSNNWAGGQYGQDLVRMMGEIEATK"
     gene            12262..12615
                     /locus_tag="JAM15_14945"
     CDS             12262..12615
                     /locus_tag="JAM15_14945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799548.1"
                     /translation="MKKSNIFSIIFPTIIMVLMFLTFATDIFNIPDIQSKSIFVVGMV
                     LIFPISFLIQGIICVLNKTNWILSLIVSLVTYIVLMYIFLNDSAYIYVLLYTAFYMIG
                     HITAKLYYKIKTFKN"
     gene            12806..13627
                     /locus_tag="JAM15_14950"
     CDS             12806..13627
                     /locus_tag="JAM15_14950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HAT6799549.1"
                     /translation="MNLIDNHIHTNFSSDGKDSMEDTIKKAISIGVRYLTFTDHLEHD
                     EDRGFCINYNDYVPVFNKFKEKYKKDIELLLGVEVGYRKHLKNEIEEIINSNPFDFVL
                     CSTHTIDNVPVPSKAYFKGLSKEDAYYKYFNSILETNREFGDYNIYGHLDYISRYGIY
                     SDNRVIYNDFKDVIDEVLKSIINNGSGIELNTSGYRYGLNAIHPNEDILKRYKELGGF
                     IVTVGSDSHRVEDICKDFDVAYDMLKYLDFKYVSLFKERETYFVNIEKVKSNNIA"
     gene            13885..15768
                     /locus_tag="JAM15_14955"
     CDS             13885..15768
                     /locus_tag="JAM15_14955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HAT6799550.1"
                     /translation="MFNKNKENITLSNQIKGTIQNSLTKEAILHIPMSNYAYGYDRET
                     LHIRLRTKKNEAKRVILRIGDQYVWDKGGAGGGNLNASGVGWSGGTNIVMNKEVETEL
                     FDYWIAKCKPLNKRSRYGFIIEGQEEKLLFTEKRIIELGNENDEKELCEIGNFFGYPY
                     LNYIDIPKVPNWVKDTVWYQIFPDRFANGDPSINPEGVDKWGAIPTRDNFTGGDLQGV
                     IEHLDYLSDLGINGIYFCPITIGKTNHRYDTVDYMEVDPTLGDKETLKKLIEEAHKRN
                     IKIMLDAVFNHIGYYSKQWQDVVQNKENSRYKNWFYIKDMSKIDTPIEQIDEKNIPYE
                     TFGCEKYMPKLNTENSEVIKYLLDVGKYWIQEFDIDAWRLDVSNEVDHVFWRKFREEV
                     KKVKPDIYILGEIWHGSLPWLMGDQFDSVMNYLMSEAMKKFFCTDEINAEEFKYMIND
                     VMVSYPIQVSEVIFNLLGSHDTTRILTYANGNIDRFKLAYMFMFVQTGCPCIYYGDEI
                     GMEGELSSISEGQRKCMEWNEEKWNKDIFDFMKKIIRLRKENKELRSISNEWVLADKE
                     NRTIILKKESISIIINNSSKNIILTLPDYLANKKVKDLYEEEIVDLKEELMLEKYKFI
                     ILK"
     gene            15992..16672
                     /gene="pgmB"
                     /locus_tag="JAM15_14960"
     CDS             15992..16672
                     /gene="pgmB"
                     /locus_tag="JAM15_14960"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HAT6799551.1"
                     /translation="MIEAFIFDLDGVITDTAYYHYMAWRKLAHKVGIDIDTKFNESLK
                     GISRMESLDRILEFGNKKYSFSEEEKVRMAEEKNNYYVSLIDEITSNDILPGIESLLI
                     DVKSNNIKIGLSSASKNAINVLNHLGISDKFDFIADAGKCKNNKPHPEIFLMSAKGLN
                     VNPQNCIGIEDASAGIDAINSANMFSVGVGNYENLKKANLVVDSTNQLKFEYIQEKYN
                     EYIVRRII"
     gene            16669..>18846
                     /locus_tag="JAM15_14965"
     CDS             16669..>18846
                     /locus_tag="JAM15_14965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HAT6799552.1"
                     /translation="MKCLFSNVDEWKIIQDKIEIKENRLAESIMSIGNGYMGMRGNYE
                     ENYSGDTHKGSYIAGVWFPDKTRVGWWKNGYPEYFGKIPNSVNYIGVRIFIDDVELDL
                     AKCKVEDFYRELDMKNGILNRRFIVNINDKKFEVRVTRFLSISVKELAVIKYSIKSLN
                     SNTKIKFVPYLDSNIKNEDSNYEEKFWNGISSSSLEYKGSILSRTKENAFNTPVFTVG
                     SMMYIKTNGDVEAVSHESDYNYCENSITMDVLKNEVASIEKYVSITSTRDYKESELLR
                     KCEDILNRELSKSYDDILNEHTKLWNKRWESADVKINGDKSSQQGIRYNLFQLFSTYY
                     GEDSRLNIGPKGFTGEKYGGATYWDTEAFCVPVYLGVADKEVTRNLLEYRYNQLEQAK
                     DNAKKLGLKGALYPMVTFDGVECHNEWEITFEEIHRNGSIVYAIYNYTNYTGDYKYIK
                     EKGIDVIIEIARFWASRVHLSTKKDLYMIHGVTGPNEYENNINNNWYTNCIAKWCLDY
                     AVENILRLEKECNECIDRNNVTREEVEFWKIISNKMYLPYDEELQIIIQNDNFLDKEF
                     VEVKDLPKENFPLNQNWSWDKILRSCFIKQADVLQGIYYFGNRFTKEEKKRNFDFYEK
                     YTVHESSLSSSIYSIIASEIDNLEKAYELYSRTARLDLDNYNNDTNDGLHITSMSGSW
                     LSIVHGFAGMRTWNETLSFDPKLPKEWKNYSFNINYRDNIINVD"
BASE COUNT         7357 a         2055 c         3407 g         6027 t
ORIGIN      
        1 ttaatatagc tataataatt tatgatatta gatggaaatt acgtaaaaat agaaaattga
       61 aaattctgaa atttttgcat attgatattt atctcataga ttcttttttg taattgtaac
      121 acgcttttat ttttaaatca atagtacatg tataaaaata aaaggaatct aaataagaaa
      181 aagatatttt taatatctgg atgtagtata gaaatatctt gaataaatta ttcttgaata
      241 aaattataaa aatttaaaat cactagaaat atgataaaat aatttaaaat acgcatttca
      301 atgacatttc aagacaagaa aataataaaa aacaaatcta aattaagcct aaatagcttt
      361 ttagttaatt ttagtagtaa aaaataaaac ttaaaaagtg tttgacaatt atgaatttta
      421 agaatataat taaattaaaa ttatacacat ataaaaatat actcctgaat caagaatgag
      481 atatttaaga ttcaaaatat atattattat acgtgaataa taaaaagtaa gaaaatttta
      541 taagggaggg gtagatgtga gtagtcaaga aagcaaacca aaaggaaatc ttatatcaaa
      601 ttttagagat gatatgagag accctaagaa aagagcaata tacacatatt caagttctat
      661 aaacttagcg tacaatttta taggttactt tgtatcaact gttacaaata tttttttaac
      721 tgatgtggca aaacttggtg taattatggc aggtggtatg caaattatac aatctttcat
      781 aaaaattgct gtagctccta taacaggtac agtatttgac aaacaaccat tcaaaaaagg
      841 aaagtattat ccatggctta gatatgcacc agcagcgtta gcattaacat atggaatatt
      901 tttcatagtt ccattaatga aaataagtcc agcattactt ttacctttga tgacagcttt
      961 attattaata gcatcttgtg ctcagcaagt agttttcact ataatttatg ctatttaccc
     1021 tgtagttgct aagacaccta gagaccgagt tataggctca actactacta atatatttaa
     1081 agaagttggt aaattcttag taggtttttc atatccgtta ttattagttt tatttgcaga
     1141 tgtattaggt ggagaaggaa tgggttattt aggtacctac ttattctttg cagcaggatg
     1201 ccttttagta ttttggtttt cttcaacaga gataataaaa tctggagcag aagaagaagt
     1261 tcttcaaaaa gaagagaagc caaagattaa agcaagtgaa atggcaaaag ctctattcac
     1321 taatgtacca cttatgatgg cattttgttt agaatttctt atatgtataa gatctatagg
     1381 attaggacct ttggctccat attattttaa atatgtaata gaagatgaac gtggattagc
     1441 agtattttta tcaatcatgc ctttggtaag tgtagcattc atgtttttcg caccagtgtt
     1501 tataaaaatc tgtagagagc aaaaactagc ttcaataatt tctttttcta tatgtgcact
     1561 atgccactta ttggttgcat ggactccttg ggggaaaact accttaggag taactatgtt
     1621 gctggcaatt ggtggaggtt tttcaaatgt agtatcaata ataaatctta atttctttgc
     1681 tggttcttgt gattatgggc attggaaatc aggaaaagac ttacctggct taagcatgtc
     1741 actatatcca gttgcaatac aagtaggagt attacttgca actactataa gaacagtttt
     1801 aatgaactca atgggatatc aagctgatat ggtagtcaca gaagcagtta aatcaggttt
     1861 tataaatatg atttcttatt ctatggcaat acctttaata atagctgttg ttatagcaat
     1921 actatatcca gtaagtgaca agaaattaaa ccaaataaga gaagagttaa atcaaagaaa
     1981 tgcttagtta aaagaaagtt aagtagatgg ttaatttaag ctattaaagt aagtagacgc
     2041 aatagcgttt atataaatga aaatacatat acagaggggg cttttaaaaa tgatagaaaa
     2101 attattgaga aataccgtaa aagaattaca tcaatatgtt ccaggtgaac caatagaaaa
     2161 agttaaggaa aaatatggtg taaaagaaat aataaaatta gcttcaaatg aaaatcctct
     2221 aggaccatca ccaaaagcaa tagaagctat gattgaaatg ttaaaacaag gtcaacttta
     2281 tccagagcca gaagctaacg aacttagaag aaaattagct gaaaagctag atttaaaacc
     2341 agaaaatttt attgttgcta atggtgcaga taacgttatc actctaatag gtgaggcttt
     2401 tataaataga ggagatgaag ttatatattg taacccaaca tttccatcat atagaactgc
     2461 aactataaaa aatgaaggga taccagtaga agtaccttta acagaagatt ataagtatga
     2521 tttacaaggt atattagata agattacaga taaaacaaaa ttaatatgtg tatgtaaccc
     2581 taataatcca acaggaacaa ttgtggatga taaagagtta gaagaatttt taaagaaagt
     2641 ccctgaaaat attataacta tattggatga agcatatata gaatttttaa cagttcctaa
     2701 ttatgtggat ggacttaagt atgtaaggga aaattataac gttatagtaa caagaacttt
     2761 ctctaaaata tatggtcttg cagggcttag agtaggatat ggtattgcta aagatgagat
     2821 aataagaact ttatttacag taaaagagcc tttctctgca aatcgtgttg ctataagtgg
     2881 agcaacagca gcacttgatg atgaagagtt tataaaagaa acatatgaat taaatagagt
     2941 tggaatggct tactttaaag aagagtttac aaaaatgggg tttgatgttg tagattcaca
     3001 atcaaatttc ctttatgtag atatgaaaac agatatacct aagttatttg aagacttgaa
     3061 aaaaagaggg tttgtaataa gaccaagtgc tacacatgca cgtgtaagta ttggaactat
     3121 ggaagaaaat aagaaatttg tagcagtttt aaaggaaata ttaaatatta aaggagagcc
     3181 aagtattgga taatagatag aaatattatg aaacggggtg tagatatgaa cttaaaaata
     3241 aacgcagaga gatgtaaaag ttgtgaatac tgcgttatat cttgtaaaaa aggagcatta
     3301 aaaatatcaa gtaagataaa taaagaaggt tatgctcatg tagaagttga tgagagtaaa
     3361 tgcatacttt gtggaatttg ctatcaggtg tgtccagata atgtttttga aataattaaa
     3421 gaaaaagcat gtcaagaggc ttagaaggag ttgggataat atgaaaaaga tgtggaaggg
     3481 gaaccacgcc attgcagaag cagccctaag aggaggttgt gaattttatg caggatatcc
     3541 aattacacca caaacagagg taatggaatt tttatcacat agaatgtctg aacttggaag
     3601 aacttttata cagtccgaaa atgagatggc tgctatatat atggtatatg gagcatatgc
     3661 aagtggaatg aggtctatga cgagttcttc aggaccagga atatctttaa aacaagaagg
     3721 gatttcttac ttatgtgcaa atcattaccc ttgtgtaatc gtaaatgtac agagatgggg
     3781 gcctggtctt ggctcattgg actcagcaca gacagactat ctaagagata ctagaggggg
     3841 aggaaatgga gattatcatt tgatagttta tgcaccaaac agtattcaag agactgtaga
     3901 tttgatgtat aactcatttg atgtagcgga aaaatacaga gtgcctgtcg aaattttgac
     3961 agaagcagct ttaggtcaaa tgatggaacc agtagaattt ccagagttta agaagagaga
     4021 aggcgattta ggttggactt atgatggaag taatagagac catgcaaagg ttgcagataa
     4081 ccaaaagcca actttttgta tggagaaacg tatgagaata actgaaaatg aacaacaatg
     4141 ggaagattat caagtagaag atgcagaata tgtgtttgta gcgttcggta taccatcaag
     4201 aacaactatg aatgctgtta gaagacttag agaacaaggt gaaaaagttg gaataataag
     4261 accaataaca gtatggcctt tcccatataa agcatttgaa aaggtaagta aagatgtaaa
     4321 aggatttatc tcagtagaat caacagacac aggtcaatta gtagaagatg ttgctttagc
     4381 ctcaaagaaa gtatgtaaag aaaatgtacc tgtgtatggt ttatttagtg gaaatcatat
     4441 accaaaaaca ttgcaagtaa tggacactta tagcaaaata aaatctggcg aaatcaagga
     4501 ggtgttctaa tatggctaca gaaaaattaa cacctagcgt tgtttcaata ccaaacaagt
     4561 tttgcccagg ttgtggtcat ggaatagtaa atcgtataat agcagaggta atagaagaac
     4621 atggatatga aaaaaatcat gtattaacat taggagttgg ttgtgtctgc aatatgaatt
     4681 ttagctggaa tggtgataag atgcaaactg cacatggtag agcttcatct acagctatag
     4741 gagttaaagt agcacttcca gatacattag taatgactta ccaaggtgat ggagatgctt
     4801 atgttatagg tctttctgaa actttaaata cagcatatag aaatcataat gtgactgtat
     4861 ttgtaataaa caataataat tttgcaatga ctggtggaca aatgtcatgg accactatgc
     4921 cgggtcaagt cacaacaaca agtgtaaatg gaagagatat aaagactact ggtagtccac
     4981 tgaaagttcc tgagatggtg gcaaacttct ttgatgtagc atatgtagca agaggttcag
     5041 ttcatagtcc aaaggaaata attaatctaa aaaaatatat aaaaaatgca atagaagctc
     5101 aattaaatgg agagggatat tccttagttg aaatattagc accttgccca actaactggg
     5161 gtgtatcact agagaaatct atcaaatgga tggaagaaga aatagtgcca tattatgctc
     5221 ttggcgaatt taagcaaagg gatggtgaat agttatggaa aaagagctag tatttgcagg
     5281 gtttggtggt caaggagttt taactcttgg tctgattgta gctgagtcag cacttgaatt
     5341 ggggaaacaa gtaacttgga tgcctgcata tggtccaact atgagaggtg gaaaagccta
     5401 tagtgtagta aagttttctg atgagagtat aggtgggcct gatatggaag aaatagatgt
     5461 tttagtagca atgaataaac catctttaga ttatataaat ttagttaaag aaggtggaac
     5521 agtagttatt aatacatctg caatagatga gaatgtaaca ttaagagaag atataagtgt
     5581 agttaaaata aattgtcagg aattagctca aaaagtaaac aatccaaaag cagcaaatat
     5641 agtagtactt ggagcattaa ttgctaaaac tgggttattt gaaaaagaat tagctttaaa
     5701 aactatgtgt gatttctttg aggaaaaagg aaaaggaaag tttaatgttc aaaatgaagc
     5761 agcattcatg gaaggctata ataacgccat ttgataaatt acccttatct taagtgattt
     5821 atctcaagat ttaataatct ttagtgccaa gagaaacttc atcttgagat aaaattcact
     5881 taaaatcaca actataaaca tataggagcg tgaatttatg agtttggaaa aacttattag
     5941 accaaaaagt attgctatag taggagtgac tgataaactt ggttttggaa gaagtgcagc
     6001 acttagtata gtaaaaagta aggaaacaga tagagtatat tatgttaatc ccaaaagaga
     6061 agaattgttt gggagaaaat gttataagac gatacaagaa gttccagaag tagtagactg
     6121 tgtagtagta tgtacgccta gaaatgtagt tccatctgta ttaaaagatt ctggagagtt
     6181 aggaacaaag gcagcagtgg tatatgctag tggatttgca gaggaaggta cagaggaagg
     6241 tacagattta gaaaatcaac ttatagaaat atcaaataca tacgatatga aaatattggg
     6301 tccaaactgc atggggttgc taaattgtat agataaggtt aatctatggg caggaggttc
     6361 taaatgggat ttagatacta aaaaacctgg tataggaatt gtaggtcaaa gtggatttat
     6421 aactgctgaa attgtttcaa gtgattattt taatatatct tatggttttt caacaggaaa
     6481 tggaaatata gttacactag aagatgcagt agatttcctt gtagatgata attatgcatc
     6541 agtaatagca atttaccttg aaggtttaaa aaatcctcaa aaatttatag atgttttaaa
     6601 aagggcagca caaaaaagaa agccagtaat aatattgaaa tcaggaaggt cagaaaaagg
     6661 tgctatttct gctgcctctc atacaggaaa tttagctggt tcgagtaaag cttttgaaag
     6721 tatttttgaa aaatatggag taatttctgt ggaaaattta gaacagttta tgtgtttagc
     6781 acaagctttt agtgttttag atggtaattt acctgcaaat tctaattttg cagcaataaa
     6841 cttctcagga ggagaaaata ctatttgtgc agatttagca gaagaaaatg gtgtagaact
     6901 tgcagaaata tcttctgaaa ctaaagaaga aatgaaaaaa tatcttccag gatttgcaac
     6961 acctaaaaat ccactagatg ctacaacagc attattccat gaaaaggata tgatagtagg
     7021 tttattacat acctttgaaa aggatgatag tgttggattt actatggtag gtgcaaatat
     7081 aagagatgaa gaaaatgaaa tgcatgaaac cctttgtaaa gctgtaagtg aagctagaga
     7141 acaaggattg aaaaaacctg tgtttgcagt tcctacactt gaaggaaata gatatttaga
     7201 ttataggact agattagaag ataatcaagt gcctataatg tcatcagttg gaactacatt
     7261 tacttgtttt aataaaatgg ctaagtttat agattatgat tattcaaaaa gaactttaga
     7321 atttaaagct gttaagaaaa gagagtcaaa taatgtagta gcattatcag aattagatag
     7381 taagattgag atgaaaaaat atggagtacc agttccagga caaggtaatg caaaaagtat
     7441 tgatgaatta gatgaaatct taaaatatat taagtatcct gttgttttaa aaataaattc
     7501 ttctgaaata ttgcacaaat ctgatgttgg aggagttaaa ataggaatta agaatagaga
     7561 tgaggcagta gatgcatata atgagatttt aactaatgta aaaaaagcaa aaccagatgc
     7621 taatattgat ggtatattag ttcaagaaat ggtagaaagt ggtatagaaa ttattattgg
     7681 tataactaat gatgaccaat ttggaccaat gttattagtc ggtttaggag gagtatttgt
     7741 agaggtattt aaagatacta cattatatcc attacctata aatcatgatg aagctattat
     7801 gatgcttaaa aaactaaaat catttaagct tttaaatggc tatagaggaa gtgagccttg
     7861 tgatattgat gctcttgcag atatgatggt caaattagga aaatatgctt atgaaaataa
     7921 ggatgaagtc aaggaaatag acttaaatcc agtgtttgta tatcctaaag gaaaaggcgt
     7981 atgtgcagta gatgccttaa tagttaaata taaatagttt ataagttttg gtattcaacc
     8041 ataattaaag caccgactga aaatcacatt ttgtaagtta gatagtgtga ttttcagtca
     8101 ccccaaattt aatttaaaaa tattttaaaa tgaaagtata gttttaagtt taattgtgaa
     8161 atagcactgt ataaacaata aaatactacg tataaaacga ataataaaag gtgttttaat
     8221 gataagaatc aatcttgatt ttcattaaaa caccttcttt attatattaa aaatttttaa
     8281 acgttatatt gtcacaggtg ggtttgttgg agctgcatat gtacgattag caaattcttg
     8341 gtcaacaaag aatagaccac cctctccagc aagtttaaca cgttttatat tgtcttcaca
     8401 atttgtttct tcttctgctt gttcagatat aaaccaaagt aagaattgag aagttctaaa
     8461 gtctgattca gagtttgcta cagctgctaa gttgtttatt aaagctgtaa cctttttttc
     8521 atgagctaac gtacgctcaa gaatatccat tgcagaagta aagtctgaat ctggcattgg
     8581 gatagaatca agctgaacct ttcctcctac attatgtaag tatttgtaaa aaaacatagc
     8641 gtggtctgtc tcttctttat attgaacata aaaccaatta gaaaatcctt taagtccttc
     8701 tgcttcaagg taagaagaca tagaaagata aagatacgca gaatataatt catggttaat
     8761 ctgctcatta agtaattttt caattttagc tgaaatcatt tttatacctc caaattttaa
     8821 atgctcttat aaaatataat aatattaaat ggaaaaatat tcaataaaag tgtttaaata
     8881 ttttacatat ttaataaaaa tttatactac cattaaaaaa attataactt acaatggcta
     8941 tagagccaat taatggtgca tttgctccaa aatttgaatg ccttacactt atttttttat
     9001 atctagaaaa acttgctgaa gcagtcaatt tttttaataa tgtattttct ataaatgtac
     9061 caggtatatt aaagtcatag cctattatta tagaactaca atcaatcaat gtaagtgtat
     9121 taactaatgc atatgatacg tatgtacaaa attcatcaag caaaaacatg gcaagactat
     9181 ctttattatt tgcctcatct attaacttga ctaaagaaaa atctttacag ttaattaatg
     9241 gggagttagg ataaatatgg ctcaatgatt caattctttt aattagatta ctgacacttg
     9301 tataataatc taaacatcca ttgttaccac aactgcacaa tggtccacta aaattaattg
     9361 atgtatgtcc tatttctcca ctttgtccta ggttgccagt atgaagttta ttttctagaa
     9421 ctagaccagc tccaatacca ttcattatgt gtaggtatat ataatttgat atatttttac
     9481 ctaaaccata cattttttct gctaatgcac ccgaattagc atcatttatc aaaaatattg
     9541 gaaaatcaga catttctttt ataaaatcta ctatatttag gtttgataca tttccaaagt
     9601 ctgggggatt tagtatggta ccatttatat catctactgg acctattgaa gaaataccaa
     9661 ttccaattat atctctcttg ttgattttca ttattttagt aaacattctt tttattatat
     9721 cttttaaaac atcatttgat agacatttag ggtaagtttc agaaagttgt tttacaatat
     9781 taccttttaa atctgaaata attaccttac atatatttct tcttattagg attccacaaa
     9841 tacaaggcga tatattagaa atatctaata aaataggttt acgacctgat gaatgtgcat
     9901 ttaaagttga tgactctatt tccctaatca tattttcatt aataagttca gtaactagat
     9961 ttgataaagt cattttagta agtcctgtag acttagctaa atcaactctg gacataggtg
    10021 tatttgtaga aagtaatttc aatattatta acttattttt aatttttaca tctttgatgt
    10081 tagaaccttg tttgttactc atcataaatc tccttaaata aagttaagtg ttttatttat
    10141 tttcaagtat actatcacct tataatagag taacattttt ttacttgaaa atatcattaa
    10201 ttagaatata tcacattata tatcataaaa catataaaaa aatgttagaa ttaaattaaa
    10261 agtgaaaagt agattgatat ataaatagta aatacttaat taaaaaaaga taatgatagc
    10321 aataattatt gttaccaaga atctactact tcaagtgtta ccttaggtat ttaagttgat
    10381 agtggtttgc acgtaataaa cttgatgtaa tatatattct taataatatc gataaaagat
    10441 ttacttaaaa ataatataga ttatgtaaac atataatcta tttattgtat acaataaaat
    10501 ttcattttgt aaaacagtga attaaatatg taatatagat atcgattttt attacaaatt
    10561 gttactaaat ataggtacat tagaacaaaa atctagtaaa ttgtaactaa aatgtaaatt
    10621 tttcctttaa tctatacaat attatggaaa ctttttgtaa tttatgatat aataacaaat
    10681 atataattat taaattataa taaatgacta tagcgtagat gtaatactat gttatagtca
    10741 tttttgaatt aaacttgata tatcaagggg gaagaatatg agaacaatta gaagagtttt
    10801 agcattaggt ttaacattag ctatatttct aataaatgta cctaatgtag atgcattaac
    10861 atcagataca attaaaggta acaatatata tgagacggct ggattaatag cagataaaaa
    10921 gagttatgat acagcaatta tggtaaatat ggataattct atagcagatg gtctttcagc
    10981 aagtggtctt gcaggtgctg ttgatgctcc aattttgctt gcacaaaaaa ataagatacc
    11041 aaatgaaaca aaacaaagat taaaaaatgt taaaaagata tacataatag gtaaagaatt
    11101 atcaataagt aagtcagtag aaactgaact aaaaaacacc ggggcacagg taactagatt
    11161 gggtggagat gacagaataa agactagtta tagtgttgct aaagaggtaa atggtatcaa
    11221 aaaagttgat gaagtgatat taactaatgc atataaagga gaagcagata caataagtgc
    11281 tgcacccgta tcagtaagag atatagctcc tatagtactt acagatggaa agagtgtgcc
    11341 tttttcaaca agcaatgtaa aaacatatgc agtaggtggg agtatatcaa tgagcactag
    11401 tttagttaat aaaactaatg ctaaaagact tggtggttca gatagatatg atacaaataa
    11461 gaaagttata aaagagtttt atccagatgc atcagaattt tatttgagtg atggatatga
    11521 tttagtaaat gcacttacag gttctacaat tgctaaggaa aatccaattg tattggtgtc
    11581 agaaagtagt gataagtcta tattagcagg agcagataag attactagat taggttcaat
    11641 aagtgacagt gtgtataata agtgtgtctc tgctgcacaa aataatggcg attcgtctac
    11701 aaaaggtgag tcacctatga aaaatgagac aagcatatta ggtcagccaa cagctagttt
    11761 agaagcgtgc ttaaaatggg caaaatctaa aaaagctaat gatttattta tagagttaat
    11821 accaatatta tatgatactg ctgttcagga aggtgttaat cctgttttgg cagtagctca
    11881 atctgcaaaa gaaactggtt tttgtaattt tggtggagta ttagatgcat catttaagaa
    11941 tccttgtgga cttaaaactt ctgtaggtgg ttctgatact gataagaatg cccattcaag
    12001 atttgatact tgggaagaag gaatattagc tcaaattcaa catttatgct tatatgcagg
    12061 acaagatggt tacccacttt caaatccagt agaccctaga catgaaaaat ctttatttgg
    12121 taaggctaaa acggttgaaa gtttatctaa taattgggct ggaggtcaat atggacaaga
    12181 tttagtaaga atgatgggag aaattgaggc aacaaaataa ttgaagatta tcaaatatcc
    12241 aataaataag gattgattat tatgaaaaag agtaatattt ttagtatcat atttcctaca
    12301 atcataatgg tgctaatgtt tttaactttt gctacagata tatttaatat tccagatatt
    12361 caatctaaaa gtatttttgt tgtgggaatg gttttgattt ttccaatttc ttttttaata
    12421 caagggataa tttgtgtatt aaataagact aattggattt tatctcttat tgtgtcttta
    12481 gtaacttata tagtattaat gtatatattt ttaaatgatt ctgcatatat atatgtttta
    12541 ctttatacag ctttttatat gattggacat ataacagcta aactctatta caaaattaag
    12601 acttttaaaa attaaattga agtatataaa agtaacatta agagaagtat ccttaatgat
    12661 tttctaaaat cagaaatagg tgcttctctt ttttgtaaaa ataaaagtat gtaaataaaa
    12721 tttaaccatt ataattttct tttaacaaat gtatacaata aacttgttgt ataattaaga
    12781 tagataaaat aaagggaggg ataatatgaa tttaatagat aatcatattc atactaattt
    12841 ttcaagtgat ggaaaggatt ccatggaaga tacaataaaa aaagctataa gtattggtgt
    12901 tagatatttg acttttacag accatttaga acatgatgaa gatagaggat tttgcataaa
    12961 ttataatgac tatgttccag tatttaataa gtttaaagaa aaatataaaa aggatataga
    13021 gttattacta ggtgttgaag tgggttacag aaaacatcta aaaaatgaaa tagaagaaat
    13081 aataaattct aatccttttg attttgtatt gtgctcaact catacaattg acaatgtacc
    13141 tgttccatca aaggcgtatt ttaaaggtct tagcaaagaa gatgcgtatt ataaatattt
    13201 taatagcata cttgaaacta atcgtgaatt tggagattac aatatatatg gtcatttgga
    13261 ttatatatct aggtatggaa tatattcaga taatagagtt atatataatg actttaaaga
    13321 tgttattgat gaggttttaa agtcaataat caataatggg agtggtatag agctaaatac
    13381 ttctggttat agatatggac taaatgctat acatccaaat gaagatattc taaaaagata
    13441 taaagaactt ggaggattta tagttactgt aggttctgat tctcataggg tagaagatat
    13501 atgcaaagat tttgatgtgg cctatgatat gcttaagtat cttgacttta aatatgtatc
    13561 tttatttaaa gaaagagaaa cttattttgt aaatatagaa aaagttaaat ctaacaatat
    13621 agcttagagt atgttttgaa gtaaattaat ggatagttaa aaagttaata gttataatat
    13681 tgtatcctct agaaaaatac tagaggtttt tattttgcta aaataactaa atagaattaa
    13741 atttaaatag tatagtttat tttaaattga atagtttatt gttgatatat tttactatta
    13801 tatattttta ttgtgatata atagtaaaat atattaacct atctttagat tatataaatt
    13861 attataaagg agggaaattt taaaatgttt aataaaaata aagaaaatat aactttaagt
    13921 aatcaaatca aaggaacaat tcaaaatagt ttaacaaaag aagctatatt acatatacca
    13981 atgagcaatt atgcctatgg ttatgataga gaaacactac atataagact tagaactaaa
    14041 aaaaatgaag cgaaaagagt aattttacga ataggagacc aatatgtgtg ggataaagga
    14101 ggtgcaggag gaggaaattt aaatgcatct ggagttggtt ggtctggtgg aacaaatata
    14161 gtaatgaata aagaagtaga aactgaatta tttgactatt ggatagctaa gtgtaagcct
    14221 ttaaataaac gctcacgata tggttttata atagaaggtc aagaagaaaa acttttattt
    14281 acagaaaaaa gaataataga gttgggaaat gaaaatgatg aaaaggaatt atgtgaaata
    14341 ggtaattttt ttggatatcc atatttaaat tatatagata tacctaaagt gccaaattgg
    14401 gtgaaagata ctgtttggta tcagatattt ccagatagat ttgcaaatgg tgacccgtct
    14461 ataaacccag aaggagtaga taaatgggga gctattccaa ccagagataa ttttacaggt
    14521 ggagatttac aaggtgtgat agaacactta gattatttga gtgatttggg aataaacgga
    14581 atttactttt gccctattac aattggaaaa accaatcata gatatgatac ggtagattat
    14641 atggaggtag accctacatt aggagataaa gagactttaa aaaaactaat agaagaagcg
    14701 cataagagaa atataaaaat aatgttggat gctgttttta atcatatagg atattattct
    14761 aaacagtggc aagatgtagt tcaaaataag gaaaattctc gatataaaaa ctggttttat
    14821 ataaaagata tgagtaaaat tgatactcca atagaacaga tagatgaaaa aaatatacct
    14881 tatgaaacct ttgggtgtga aaaatatatg cctaaactta atacagaaaa ttcagaagta
    14941 ataaaatatt tattggatgt aggcaagtac tggatacagg aatttgatat agatgcatgg
    15001 agattagatg tttcaaatga agtagaccat gttttttgga gaaagtttag agaagaagtc
    15061 aaaaaagtaa aaccagacat ttatatattg ggagaaattt ggcatggtag tttaccatgg
    15121 ctaatgggtg accaatttga ttcagttatg aattacttga tgtcagaagc catgaaaaaa
    15181 ttcttttgta cagatgagat aaacgccgaa gaatttaagt atatgataaa tgatgtaatg
    15241 gtaagttatc caatacaagt tagtgaagtt atttttaatt tacttggaag tcacgatact
    15301 acaagaatat tgacttatgc taatggaaat attgatagat ttaaacttgc atatatgttt
    15361 atgtttgtac aaacaggatg tccttgtata tactatggtg atgaaatcgg aatggaagga
    15421 gaattaagtt caatatctga aggtcaaaga aaatgtatgg aatggaatga agaaaaatgg
    15481 aataaggata tatttgattt tatgaagaag attattagac ttcgtaaaga aaataaagaa
    15541 cttaggtcta tatcaaatga atgggtgtta gcagataagg aaaatagaac gattatattg
    15601 aaaaaagaat ctatttctat aataataaat aattcatcta aaaatataat tttgacgtta
    15661 ccagattatt tagcaaataa aaaagtaaaa gatttatatg aagaagaaat agttgattta
    15721 aaagaagaac taatgttaga gaaatacaag ttcattattt taaaataata caaaaagtat
    15781 ttattttaga tttcatgtta aattattata cagtttaaac aagtctttat aaaacataaa
    15841 aaaatatggt ctacaagtga gtgaattgaa agtagatttt aaattaaaga ctgagttaga
    15901 gtagataatt ttataaataa tatcttaaat acaagataga aaataaattg attattagtc
    15961 taaaaatttc ttgtagaaag aggaaataag aatgattgaa gcatttatat ttgatttaga
    16021 tggtgtaatt acagatactg catattatca ctatatggct tggagaaaac tagcccataa
    16081 agttgggata gatatagaca caaaatttaa tgaatcttta aaaggcataa gtagaatgga
    16141 gtcattggac aggatattag aatttggaaa taagaaatat tcattttcag aagaagaaaa
    16201 agtgagaatg gctgaagaaa aaaataatta ctatgtatca ttgatagatg agataacttc
    16261 aaatgatatt ttgccaggca tagaaagctt gttaattgat gtaaaatcta ataatataaa
    16321 gataggtcta tcttctgcaa gtaagaatgc aataaatgta ttaaatcatt tgggtataag
    16381 tgacaaattt gattttatag ctgatgcagg aaaatgtaaa aacaataaac cacatccaga
    16441 gatatttctt atgtcagcga aagggcttaa tgtaaatcca caaaattgta tagggataga
    16501 ggatgcaagt gcaggtatag acgctataaa ctcagctaat atgttttctg ttggtgttgg
    16561 aaattatgaa aacttaaaaa aagcaaattt agttgtagat tcaacaaatc aattaaagtt
    16621 tgaatatata caagaaaagt ataatgagta tatagttagg agaattatat gaaatgttta
    16681 tttagtaatg tagatgagtg gaagattata caagataaga ttgaaatcaa agaaaataga
    16741 ttagcagagt ccataatgag tataggcaat ggatatatgg gtatgagagg aaactatgag
    16801 gaaaattata gtggagatac acacaagggg tcttatatag ctggagtatg gtttccagat
    16861 aaaactcgtg ttggttggtg gaaaaatggg tatccagaat actttggtaa aattcctaat
    16921 tcagtcaact atataggtgt aagaattttc atagatgatg tagaattaga tttagcaaaa
    16981 tgtaaagtag aagattttta tagagaatta gatatgaaaa atggtatttt aaatcgtagg
    17041 tttattgtaa atataaatga taaaaaattt gaagttaggg ttactaggtt tttaagtata
    17101 tctgttaagg aacttgcagt aattaaatac agtataaaat cattaaattc taatactaaa
    17161 ataaaatttg taccatattt agattcaaat ataaaaaatg aagattcaaa ctatgaggaa
    17221 aagttttgga atggaatttc ttcaagttct ttagaatata aaggtagtat tctttctcga
    17281 acaaaggaga atgcatttaa tacaccagta ttcactgtgg gttcaatgat gtatattaag
    17341 acaaatggtg atgtagaagc tgtatctcat gagagtgatt ataattactg tgaaaattcg
    17401 ataacaatgg atgttttaaa aaatgaggtt gcaagtatag aaaaatatgt atctataact
    17461 tcaactagag attataagga aagtgagcta ttaagaaaat gtgaagacat tttaaataga
    17521 gaactatcta aaagttatga tgatatatta aatgaacata caaagttatg gaataaaaga
    17581 tgggaaagtg cagatgtaaa aataaatgga gataaaagta gccaacaagg tataagatat
    17641 aatttattcc aactattttc aacatattat ggagaagatt cgcgattaaa tataggtcca
    17701 aaaggattta ctggtgaaaa gtatggagga gctacttatt gggatacaga agcattttgt
    17761 gttccagtat atctaggtgt agcagataag gaggtaacta gaaatctttt agaatatagg
    17821 tacaatcagt tagaacaggc aaaggataat gcaaaaaaac tagggcttaa aggtgcttta
    17881 tatccaatgg taacatttga tggagtagaa tgtcataatg aatgggagat aacatttgag
    17941 gaaatccacc gaaatggaag tatagtatat gcaatatata actatacaaa ttatacaggt
    18001 gactataaat atataaaaga aaaaggaata gatgtaataa tagaaatagc tagattttgg
    18061 gcaagtagag ttcatttgtc tacaaaaaaa gatttgtata tgatacatgg agtaacaggt
    18121 ccaaacgagt atgaaaacaa tatcaataat aattggtata ctaattgtat agctaaatgg
    18181 tgtttagatt atgctgtaga aaatatctta cgattagaga aagagtgtaa tgaatgtatt
    18241 gacagaaata atgtgactag ggaagaagtt gagttttgga aaataatatc aaataaaatg
    18301 tatctgccgt atgatgagga actacaaata ataattcaaa atgataattt tttagataaa
    18361 gaatttgtag aagtaaagga tttaccaaaa gaaaattttc ctcttaatca aaattggtct
    18421 tgggataaga ttcttaggtc gtgttttata aaacaagcag atgtattaca gggaatttac
    18481 tattttggaa atagatttac taaagaagaa aaaaagagaa attttgactt ctatgaaaaa
    18541 tatactgtcc atgaatcttc tttatcttct agtatttatt ctattattgc ctcagaaata
    18601 gataacctag aaaaggctta tgaattatac tcaagaacag ctaggcttga tttagataat
    18661 tacaataatg atacaaatga tggactgcac ataacttcaa tgtctggttc atggctttcc
    18721 attgtacatg gatttgcagg catgagaaca tggaatgaaa ctctatcttt tgaccctaag
    18781 ttgccaaaag agtggaaaaa ttattctttc aatataaatt atagagataa tattattaat
    18841 gtagat
//
LOCUS       DACTZW010000082        18728 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.082, whole genome shotgun sequence.
ACCESSION   DACTZW010000082 DACTZW010000000
VERSION     DACTZW010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18728)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18728)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18728
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.082"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(348..1619)
                     /gene="sleC"
                     /locus_tag="JAM15_14970"
     CDS             complement(348..1619)
                     /gene="sleC"
                     /locus_tag="JAM15_14970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore cortex-lytic protein SleC"
                     /protein_id="HAT6799553.1"
                     /translation="MQDGFLTVSIIDATNNRPIQNAVVNIYSMSNGSQSSSTLYQNLR
                     SNESGQVTGLVLPAPDVDYSLQPSDVRPYSQYIVEAIADGYETVVIEGTQLLATIVAR
                     QGVPMSPRTRSKRSFSRQSELIFDIGEHTLYGTYPPKIPESNLKPLPPPTGFVVLDNP
                     VVPEFIVVHDGLPEDSSAPNYWIPFKEYIKNIASSEIYSTWPEQTIYANVIAIISFTL
                     NRVFTEWYRNKGYNFTITSTTAYDHKFINNRNLFEPINVVVDAIFNTFIKRPPTSRQP
                     LLAQYCDGQKSQCPDQMTQWGSKDLGDQGYDYESILRYFYGDEIVFERAPIVSGVPVS
                     FPGTTLQVGSSGQYVRTIQNQLNAISNSYPAVPKVIEDGIYGTDTENAVKIFQGIFGL
                     PQSGVVDFKTWYEISRVYVATTRIASLNPLI"
     gene            1864..2580
                     /locus_tag="JAM15_14975"
     CDS             1864..2580
                     /locus_tag="JAM15_14975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HAT6799554.1"
                     /translation="MKLDLFLLAIVPILIGMFWIRSKDRYCREPLIHLIKFFLIGAFL
                     SVIIILLENLLMKFNVFEEYSELIYVSFVVAGLVEEGVKALILIPALIKEKHFTEKLD
                     GIIYSVFLALGFATIENMVYIFSESRNLALQVGINRAVISIPAHVMFAITMGYYISKY
                     KFEGNKNKRREYLFMAVLIPILLHGVFDFILMIEYRWAIILLIVYVIILWKINLDKLE
                     KYMNHSKKVFFGNLRKKKKK"
     gene            2659..3969
                     /locus_tag="JAM15_14980"
     CDS             2659..3969
                     /locus_tag="JAM15_14980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylase"
                     /protein_id="HAT6799555.1"
                     /translation="MTELPKEFLEDIEEILKDEYDDFIKSYEESKTTGLRINTLKIDK
                     KKLFDLELFDLNQIPWAEEGFYYDDKIDRPGRNPLHEAGAYYLQEPSAMSVIPKADIK
                     EGEKVLDMCAAPGGKSTYILSKLNDTGLLVSNEINASRIKALGENLERFGARNCIITN
                     TDSNSLRKTFNGYFDKVIIDAPCSGQGMFRKDEVAISDWSYAKVVECQSIQKEIIRDG
                     YKMLKKDGILIYSTCTFSREENEHVINEFISEYPHAELIEMERLWPHKIKGEGHFVAK
                     IKKLEEEECNVKELKIKNLDKEIKDYREFEKKFLKVDFYSNKKNKFYLRGENLYLLPE
                     IYPDTKKLKVLRYGLHLGVLKKNRFEPSHALSHYLKVEDVKNVENFSVQSESILKYLK
                     GDVVNSNDSRGWVLVSVEGIPLGWGKESSGVIKNHYPKGLRKVF"
     gene            4069..4605
                     /gene="lepB"
                     /locus_tag="JAM15_14985"
     CDS             4069..4605
                     /gene="lepB"
                     /locus_tag="JAM15_14985"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAT6799556.1"
                     /translation="MGEAVKKEVVEWIKVIVIALVLAFAITRFIVPTIVKGESMYPTL
                     VERDYLIVNRIAYKVGEPKYKDIIVFKTDLTEENGKKKDLVKRVIGVPGDHVKIQDSK
                     VYVNDKLLDETSYIHNNRTDGDIDIVVPEGKLFAMGDNREKSLDSRYDEVGLVDEHTI
                     LGKVLVRLYPFSKIGTID"
     gene            4771..5307
                     /gene="lepB"
                     /locus_tag="JAM15_14990"
     CDS             4771..5307
                     /gene="lepB"
                     /locus_tag="JAM15_14990"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAT6799557.1"
                     /translation="MNETIKEEIVEWIKIIITALFFAFIITRFIKPTLVNGESMYPTL
                     KSHDYLVANRMTYKLSEPKCGDIMIFKTDLLQENGRKKELVKRVIGVPGDHLKIKDSK
                     VYINGKLLNEVSYIHDNYTEGDIDMVIPKGKVFAMGDNREVSLDSRYKEVGLVDEENI
                     KGKVILRVFPFTDIGIFE"
     gene            5317..6072
                     /locus_tag="JAM15_14995"
     CDS             5317..6072
                     /locus_tag="JAM15_14995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM barrel protein"
                     /protein_id="HAT6799558.1"
                     /translation="MAVGIASLLFNIEEALNICESIKQITHLEIGIDNISECSELCKY
                     KERISKLGLSIGIHLPMELNTCENIEYIRNSWINFIEKIEFELKGFDIRYFNLHLGYV
                     MTNRVRKNRDKYLGNSVDFLDKLNTNSYVCIENTYSKGGDFSNIGNISYDFEYIFKRI
                     KNSKICFCYDTGHCLIDEDTYVKNLKDKIRLIHLSDNDGINDTHVGIGRGILSEEGIK
                     EVLTLDAEYLVLEINYEDIEDTISKLNNIVREG"
     gene            6146..7813
                     /locus_tag="JAM15_15000"
     CDS             6146..7813
                     /locus_tag="JAM15_15000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside kinase"
                     /protein_id="HAT6799559.1"
                     /translation="MKKINLKIEGKDKEYSLEENSPGIRLGDIAKEFCDEHKGYITLA
                     VVDNKLKELNCRVKKDCEINFLDTTNEDGERVYFRVMSFIFVMACREIFWDSRVTIEH
                     SLSDGLYCEVHIDRKLKEADVENIKNKMKEIVNNDYVIEKIEVTRNEAISIFENNEMY
                     EKAELLKYKEYDSAKVYKCRNYIDHFYGYMLPSTGYIKSFDIKLYNGGVIILGPSEED
                     KTLPMKFVPQPKLSSVYYEAEEWSRLMGIDKVVSLNKIIENNEYGDIIRTFEALHEKK
                     LSQIADMIKDGNKRVILIAAPSSSGKTSFAHRLSIHLRVNNLNPISISLDDYFIDRKH
                     TPLDEYGNYDFESIYAIDLEKFNLDLKKLLAGEEIDDIRFNFKEGKREYTGKKIKIDS
                     NQPIILEGIHGLNPILTSSIPDEDKFKIYISALTQINLDDHNRIPTADLRMIRRIVRD
                     YNFRGYSADNTILQWASVRRGEKKNIFPYQEEADAIFNSACVYELAVLKRFAKPLLEE
                     IKEDNPAHIEATRLLKFLQYFVELDDTSDIPGISILREFIGGSKIVD"
     gene            8330..9259
                     /gene="glsA"
                     /locus_tag="JAM15_15005"
     CDS             8330..9259
                     /gene="glsA"
                     /locus_tag="JAM15_15005"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HAT6799560.1"
                     /translation="MNTLDETLLKEIISSNKKYTNYGQVASYIPELKNARRNDLGICI
                     IDSENNLYSAGNCSTKFTIQSISKPIVLAMALMDNDWEDVFSNVGMEPSGDPFNSIMK
                     LEINDTKKPCNPMINAGAIVTTSLINGSCLEEKEERMLSFFRKLAKNDNIGINYDVYK
                     SEKMTGDRNRAMAYLLKSDGFIRGNVEDVLDLYFKQCSIEIDSVDLARIGINLANYGV
                     DIENGEHLMSEMVSRIVKTFMMTCGMYDASGEFAIKVGIPAKSGVGGGIMASVPGRMG
                     IGVYGPALDKKGNSVAGVKVLEELSNKLKLNIF"
     gene            9357..9920
                     /locus_tag="JAM15_15010"
     CDS             9357..9920
                     /locus_tag="JAM15_15010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6799561.1"
                     /translation="MKEVLVLRDLECIKAIAHPRRIDILKAFDKSPLSAKQLSQLLEE
                     PHAKINYHIKMLYKVGILELVEEKIKSGIVEKYYYPSAKNVVIGNRILNFSLDNGEEK
                     EELYISKFENMSEVFYKAAEEDVLENENIVDYHDISLTHDELVELSDTMKSKIDEILN
                     KRQHNVEGSKYDIAMVIVPTLEEECPS"
     gene            10410..11246
                     /locus_tag="JAM15_15015"
     CDS             10410..11246
                     /locus_tag="JAM15_15015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HAT6799562.1"
                     /translation="MIKLGTHLSIAKGFANAAETAVYIGANTFQFFSRNPRGGNAKEF
                     DEKDIIKFQEIRKENNFAPLLAHAPYTMNLGGTKDDVYEFATRVIDEDIRRMDSLGIE
                     YMCFHPGSHIGGGVDFGIDRIVKGLNNAIKGDENITILLETMSGKGTEIGFKFEQLKS
                     IIDKIEHKEKIGVCLDTCHIFSAGYDIVNDLDGVLEEFDKVIGIERLKTVHLNDSMMP
                     FGDKKDRHAPIGEGKIGLKALIDFMEHPSLKHLPFFLETPFDDEGHKRELKMIKEILS
                     SK"
     gene            11530..12525
                     /locus_tag="JAM15_15020"
     CDS             11530..12525
                     /locus_tag="JAM15_15020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HAT6799563.1"
                     /translation="MRNLGNTNMKIKRVGFGGIPIQRITQDDTNLVINELEKQGINFI
                     DSARGYTISEEAIGIAIEGKRDKFFLATKSMSRDYDSMKRDVEISLNNFKTDFIDLYQ
                     FHNVKEEEYDNLFKDKMAYSALLEAKEQGKIKHIGITSHNLNTIEKAIEDGKFDTIQF
                     PYNIVEGQADEVFKKAHEKGIGIIVMKPLAGGALDNATLAIKYILSKDYIDVVIPGME
                     SVEQVRQNVAVLENLVLDEKDNKEIEEIRNSLGKKFCRRCEYCMPCAVGINIPLSFLC
                     EGYYTRYGLKEWAKEKYEVMDVKPTECIDCGLCESRCPYELPIREMLKTVVEKLG"
     gene            complement(12782..13186)
                     /locus_tag="JAM15_15025"
     CDS             complement(12782..13186)
                     /locus_tag="JAM15_15025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HAT6799564.1"
                     /translation="MIKITIPGRPISKSNFKLHNINGQAWMPSKGKYSKYLAYENMIA
                     GFINQQYQGETVEENLITVLKLFFPNKRMGDLHNYPKSICDGIEKSGIIKNDKQLKPV
                     FLFDFIDKDNPRVEIELYPVSKYDISYNIFEK"
     gene            14025..14939
                     /gene="queG"
                     /locus_tag="JAM15_15030"
     CDS             14025..14939
                     /gene="queG"
                     /locus_tag="JAM15_15030"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HAT6799565.1"
                     /translation="MDNKELKAFCNLIGLNCVGVAGVDKYDNLEKILKDRQQKGYLTG
                     MEEPIIENRINPRHIMKDANSIIVCAFPYHINRQEKNKNSNLSKYCHGKDYHIVVKDF
                     LQQICDYISKTVTDFKYKLFADNGPLVDRYLAYLSGIGYFGINNNIITDEYGSYVFIG
                     YIVNNYKFEEDKPLEKSCFKCGKCVKYCPGNAILGNYDMNPQKCLSYITQKKGDLSEK
                     EKVVLKNGKKVFGCDICQEVCPHNVEISTTHILEFKENIIDYLDYDEIQNISNKEFKR
                     RYGDRAFSWRGRNIIKRNMEIILDKYDD"
     gene            15045..17282
                     /locus_tag="JAM15_15035"
     CDS             15045..17282
                     /locus_tag="JAM15_15035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAT6799566.1"
                     /translation="MKYNNTSEINPLDYILGQERAVEAMELGLKINNPAYNIYIAGEP
                     GTGKSTYALKVLNEYASKKNTHKDWCYIYNFENPREPIIVELEKGFGRELKKDMEKLI
                     ESLLEDFKNAFESENFEIEKNKLLDEYEIEKDMLLKQIKKYGEEKGFKLKQSKMGIVF
                     IPLKEEEDESDESDEEFYKAKRELENMAIQVVYKIRNLEEIAEKAVLELEEEIAKLVV
                     EPHIKRLCEKYENYDKIQTYLENIKKDIIEYMYLFYLDEEELKDKYDKEHFIKYKINL
                     FVDNGSSKNKESAPVVVEINPSPANLFGKAEYDYANGNIKTDFTKLLSGAFHRANGGY
                     LVLYADQLLKYTMSWEILKKTLQTKKVILETQTAIKPENMPLDVKLVLIGSHYIYDIL
                     YRYDEDFEKYFKVFVDFDSEMDKNEDNEEGIARFIAYQCDKNNLRHFTKSAVEEVIKF
                     STRLSGDLEKLSTKFNKIMEVVIEGSAYAEFRNSEYTEQCDVKKAISEKRKRINRVET
                     HMDESIENGFTLIETEGRKVGVINGLSVLSTGEYSFGRASRITATTSPGSKGIVNIER
                     EVNMSGSIHNKGVLILGGYLSENFAQDLLLSLNAYVCFEQNYGGIDGDSASSAELYVL
                     LSSLSGVSIKQNIAVTGSINQKGDIQVVGGISEKIEGFYSICKTKGLNGEQGVIIPRK
                     NQRNLVLSDEVNDAVRDGKFKIYTVERVEEAIEILTDVKFEEIKKLVKEKLISFSKIQ
                     TVSKE"
     gene            17991..18647
                     /gene="nth"
                     /locus_tag="JAM15_15040"
     CDS             17991..18647
                     /gene="nth"
                     /locus_tag="JAM15_15040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007286415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HAT6799567.1"
                     /translation="MKNESANKKDVNKILDELEKLYPDAKCELNYGTAFELLIATILS
                     AQCTDVRVNKVTSELFKKYNTARDFANLSIEEISKEIKSCGLYKSKSQKIKDTSEQLC
                     ELYDGEVPDSLEKLIKLPGVGRKTAGVVLSNAFNHPAIAVDTHVFRVSNRIGIVDEPN
                     PQKTEFALMEAIPKERWSHSHHVLIFHGRRMCKARNPECASCPIKEDCNYYKELNETK
                     "
BASE COUNT         7446 a         1809 c         3487 g         5986 t
ORIGIN      
        1 ttaaataata aggagtaata ttctaagtga gaagtagcat tttaaataat aagtgagatt
       61 ttaaataaaa agtaagcttt tcgttagaat agcattttat taaacttaaa aataaatata
      121 atattttaaa gaaatctaag ttgctaagca ctgtttttaa gaagcttaaa atcccccatt
      181 taaagtttta aggttctaaa aaaacaagtt ataactaaaa aatggctgtt aagactacaa
      241 tacttataag taaaaatact tatggtatat attagttcat aacagccatt tttattttaa
      301 attaataatt ttattcaata atttgagttt atgttctaaa tcaagcttta aattaaagga
      361 tttaaagaag ctattctagt tgtagctaca taaactctgg atatttcata ccatgtttta
      421 aaatctacta ctccgctttg aggtaaacca aagattcctt ggaatatctt aacagcgttt
      481 tctgtatctg ttccatagat accatcttct ataacttttg gtacagctgg ataagaatta
      541 gatatagcat ttaactgatt ttgtatggtt ctaacatact gcccagaaga accaacttgt
      601 agtgtagtac cagggaatga cactggtaca ccacttacta taggtgctct ttcaaatact
      661 atctcatctc catagaaata tcttagtata ctctcatagt catatccttg gtcacctaag
      721 tctttactgc cccattgagt catttggtca ggacattggg atttttgtcc atcacaatat
      781 tgtgctaata gtggctgtct tgatgtagga ggtcttttta taaaagtatt aaaaatagca
      841 tctacaacta cgttaattgg ttcaaataag tttctattat ttataaactt atggtcgtat
      901 gctgttgttg aagttattgt aaagttatat cctttatttc tataccattc agtaaagact
      961 ctatttaaag taaatgatat tatagctatt acatttgcat agattgtctg ttcaggccaa
     1021 gttgaatata tttcagatga cgctatgttt ttaatgtact ctttaaatgg aatccaatag
     1081 tttggagctg atgaatcttc tggcaaacca tcatgaacta ctataaattc aggcactaca
     1141 gggttatcta atacaacgaa accagtagga ggtggtaatg gttttaagtt actttctgga
     1201 atcttaggag gataagtacc atatagagta tgttctccta tgtcaaaaat caactcactt
     1261 tgtcttgaga aagaacgctt acttcttgtt ctaggagaca tgggaactcc ttgtcttgct
     1321 acaattgtag ctaacaactg cgttccttct atgacaactg tctcatatcc atctgctatg
     1381 gcttccacta tatactggct ataaggtcta acatcagatg gttgtagaga gtaatctaca
     1441 tctggtgctg gtaatactaa accagtcact tgaccagatt cattacttct taggttttgg
     1501 tataaagttg atgagctttg gctaccatta gacattgaat atatgtttac tactgcattt
     1561 tgaataggtc tattgttagt agcatcaatt atgcttactg ttaagaaacc atcttgcatc
     1621 aaatcaccct ttctttaaat gaatttagtt cccttatatt tcaagatatg aatatagctt
     1681 gaaatttgtt aaataatata gatataaatt taaatttttt tgagtatttg agtatatttg
     1741 tatttaaata atttaaaata atttaatgta tattttagta tgtatttaaa acacaaataa
     1801 gctaaaaata agtagatgat ataaatcata aataaatcaa aaattttgaa aggaaaataa
     1861 tctatgaagc tagatttatt tttattagca atagttccta tattgatagg gatgttttgg
     1921 ataaggtcta aagatagata ttgtagagaa cccctaatcc atctaattaa atttttttta
     1981 ataggtgctt ttctaagtgt tataattata cttttagaaa atttactgat gaagtttaat
     2041 gtatttgaag agtattcaga actaatatat gtatcatttg tagttgcagg acttgtagaa
     2101 gaaggtgtaa aagctctgat actgattcct gccctaatta aagaaaaaca ctttactgaa
     2161 aagttagatg gtattattta ctctgtattt ttagctttag gatttgcaac aattgaaaat
     2221 atggtttata ttttttctga aagtagaaat ctagcactgc aagttggtat taatagggca
     2281 gttatctcta taccagctca tgtaatgttt gcaattacta tgggctacta tatttctaag
     2341 tataaatttg agggaaataa aaataaaaga cgtgagtatt tgtttatggc agtgttaatt
     2401 ccaattttat tacatggagt ttttgatttc atattgatga tagaatatag atgggctatt
     2461 atattactta tagtttatgt aataattttg tggaagataa atcttgataa acttgagaaa
     2521 tatatgaatc actctaaaaa agtgtttttc ggtaatctta ggaaaaagaa gaagaaataa
     2581 aatttaaagg aaagacataa ataattaaag tataataaat gacacacaag taaagcagat
     2641 tgaaggggga ttatagattt gacagaatta ccaaaggaat ttttagaaga tattgaagaa
     2701 atactaaaag atgaatatga tgattttata aaaagttatg aggaaagtaa gactactggg
     2761 cttagaataa atactttaaa aattgacaag aaaaaattat ttgatttgga gttgtttgat
     2821 ttgaatcaaa taccatgggc agaagaaggt ttttattatg atgataaaat tgacagacct
     2881 ggtagaaatc cactgcatga ggctggagca tactatttgc aagagccttc tgcaatgagt
     2941 gtaataccaa aggcagatat taaagagggt gaaaaagttc tcgatatgtg tgctgctcct
     3001 ggtggaaaat ctacatatat actatctaag ctaaacgata caggtttatt ggtttctaat
     3061 gaaattaatg ctagtagaat taaggctcta ggggaaaatt tagagcgatt tggagcgaga
     3121 aattgtatta taacaaacac cgattctaat agcttaagaa agacgtttaa tgggtatttt
     3181 gataaggtta ttatagatgc accttgttct gggcaaggta tgtttaggaa ggatgaggtt
     3241 gccatatcag attggagtta tgcaaaggta gtagaatgtc aatccatcca aaaagagatt
     3301 atcagagatg gatataaaat gttaaagaag gatggcattt taatttactc aacttgtact
     3361 ttttcaaggg aggaaaatga gcatgttata aatgagttta tcagtgaata tccacatgca
     3421 gaacttattg aaatggaaag attatggcct cataagataa agggagaagg tcattttgtt
     3481 gccaaaataa aaaaattaga agaagaagaa tgtaatgtca aagaattaaa aataaaaaat
     3541 ttagataaag aaataaagga ttatagggag tttgaaaaga aatttttaaa ggttgatttt
     3601 tatagtaata aaaaaaataa attttattta agaggagaaa atttgtacct acttcctgaa
     3661 atatatccag atacgaaaaa actaaaagta ttgagatacg gtttgcattt aggggtttta
     3721 aagaagaata gatttgagcc ttctcatgca ctatctcatt acttaaaagt tgaagatgta
     3781 aaaaatgttg aaaacttcag tgtacagagt gaatcaattc ttaaatattt aaaaggggat
     3841 gttgtgaatt ctaatgatag tagaggatgg gttttggttt cggttgaagg aataccttta
     3901 ggttggggaa aagaatcttc tggtgtaatt aagaatcatt atcctaaagg tcttagaaaa
     3961 gtattttaaa ctattagaaa aaagaagtat aatatttata ttgtaggttt atggtagatt
     4021 attttgctgt agattgactt aatatttaac acagaggaga cgattttagt gggtgaagca
     4081 gttaaaaaag aagttgtaga atggataaaa gtgattgtca tagctcttgt tttggcattt
     4141 gcaataactc gttttatagt gccaacaata gtcaaaggag aatcaatgta tcctacatta
     4201 gttgaacgtg attatttgat agttaacaga attgcgtaca aggtaggaga gccaaaatac
     4261 aaagatataa tagtatttaa aaccgactta acagaggaaa atggaaagaa aaaagattta
     4321 gtaaaaagag ttatcggggt tcctggtgac catgtaaaaa tacaagactc caaggtatat
     4381 gtaaatgata agttgttaga tgagacttcc tatatacata ataatcgtac tgatggagat
     4441 attgatatcg tagttccaga aggaaaatta tttgcaatgg gagataatag agaaaaaagt
     4501 ttagatagta gatacgatga ggttggattg gtcgacgagc ataccatttt aggaaaggtt
     4561 ctagtcagat tgtatccatt ttctaagata ggaactattg actaaacata taaaatttgg
     4621 agcaatcgct gattagctga aatcaccaga ccatacacaa tagttgtcta tataaaaaag
     4681 acaacacctt atttagtaga cttatctaaa agatagtgtt taagagacat tatcaataaa
     4741 gataatataa ctataaagga gaatttgtga atgaatgaaa ctattaaaga agagattgta
     4801 gagtggataa aaataattat tactgcactt ttttttgcat ttattataac tcgttttata
     4861 aaaccaacac tagtaaatgg agaatcaatg tacccgacac ttaaatcaca tgattatttg
     4921 gtagcaaata ggatgacata taagttatca gaaccaaaat gtggagatat aatgatattt
     4981 aagactgatt tattacaaga gaatggaagg aaaaaagagc ttgtaaaaag ggttataggt
     5041 gttcctggtg accatctaaa aattaaggat tctaaggttt atataaatgg taagttatta
     5101 aatgaagttt catatataca tgataattat actgaaggcg atattgatat ggtgattcct
     5161 aagggaaaag tatttgcgat gggagacaat agagaagtta gtttagacag tagatataaa
     5221 gaagtgggat tggtagatga agaaaatatt aaaggaaaag ttattttaag agtatttcct
     5281 tttacagata taggtatttt tgagtaggtg atttgtatgg cagttggtat agcgtcctta
     5341 ctgtttaata ttgaggaggc tttaaacatt tgtgagagta taaagcaaat aactcattta
     5401 gagattggaa ttgacaatat atctgaatgt agtgagttat gtaaatataa agagagaatt
     5461 tctaagttag gattatctat agggatacac ttgcctatgg aattaaatac ttgcgaaaac
     5521 atagagtata tacgaaattc atggataaat tttattgaga agatagaatt tgaactaaaa
     5581 ggatttgata taaggtattt taaccttcat ttgggatatg ttatgacaaa tagagttaga
     5641 aagaatagag acaaatattt aggaaatagt gtggattttt tagataaatt aaatacaaat
     5701 tcatatgtat gtatagagaa tacttattca aaaggtggtg atttttcaaa tattggaaat
     5761 atatcttatg attttgaata tatatttaag aggattaaaa attctaagat ttgtttttgt
     5821 tacgatactg gacactgttt aattgatgag gatacttatg taaagaactt aaaggataaa
     5881 ataagactga tacacttaag tgataatgat ggtatcaatg atacacatgt tggtatagga
     5941 agaggaattt tatctgaaga ggggattaaa gaggtcttaa cattagatgc agaatattta
     6001 gtattagaaa taaattacga agacattgaa gatactataa gtaaattgaa taatattgta
     6061 agagagggtt aaatacctct ctttatcttg ttgatatgcc tcattaacta aaatttatat
     6121 tcatcaaaag gaaggagatg ttgaagtgaa aaaaataaac ttaaaaatag aaggaaaaga
     6181 taaggaatat tcattagaag aaaattcccc tggaatcaga ttgggagata tagcgaaaga
     6241 attttgtgat gagcataagg gttatataac acttgcagtt gtagacaata aactaaaaga
     6301 gctaaattgt agagttaaga aggattgtga gataaatttt ttagacacta ctaatgaaga
     6361 tggagagaga gtttacttta gagtcatgtc atttatattt gtaatggctt gtagagaaat
     6421 cttttgggat agcagagtta caatagaaca ttcactatca gatgggctat attgtgaagt
     6481 tcatatagat agaaagctta aagaagcaga tgttgaaaat ataaaaaaca agatgaaaga
     6541 gatagtaaac aacgattatg ttatagaaaa aattgaagtt acaagaaatg aagctatttc
     6601 tatatttgaa aataatgaaa tgtatgaaaa ggcagagctt ttgaaataca aagagtatga
     6661 tagtgctaaa gtatataagt gtagaaacta tatagaccat ttttatggtt atatgttgcc
     6721 atcaactggt tatataaaat catttgatat taagctttat aatggaggcg ttataatttt
     6781 agggcctagt gaagaagata agactcttcc tatgaagttt gtacctcaac ctaagctatc
     6841 aagtgtatat tatgaagcag aagaatggtc aagacttatg ggaattgaca aggtagtatc
     6901 tcttaacaaa ataatagaaa acaatgaata tggagatata ataaggacat ttgaagcatt
     6961 gcatgaaaag aagttatccc aaatagcgga tatgataaag gatggcaata agagagtaat
     7021 tttaatagca gctccatctt catctggaaa aacaagtttt gctcacagat tatcaataca
     7081 tcttagagta aataatttaa atcctatttc aatttcttta gatgattatt ttatagatag
     7141 aaaacatact cctttagatg aatatggaaa ttatgatttt gaatcaattt atgcaataga
     7201 tttagagaag tttaacttag acttaaagaa acttttagct ggtgaagaaa ttgatgatat
     7261 aagattcaat tttaaagaag gtaagagaga atacactggt aaaaaaataa agatagattc
     7321 aaatcagcca attatattag aaggtataca tgggctaaat cctattttaa catcatctat
     7381 accagatgaa gataaattta agatatacat aagtgccctt actcaaataa atttggatga
     7441 ccataatcga atccctactg ctgatttgag aatgataaga agaattgtta gagactataa
     7501 ttttagagga tatagtgctg ataatactat tttacaatgg gcatcagtta gaagaggaga
     7561 aaagaagaat atattcccgt accaagagga ggcagatgct atatttaact ctgcttgtgt
     7621 atatgaattg gcagttttaa aacgatttgc gaaacctttg ttggaagaga taaaggaaga
     7681 taatcctgca catattgaag ctactagatt actaaagttt ttgcagtatt ttgttgaatt
     7741 ggacgatact tctgacatac caggtatttc aattcttagg gaatttattg gaggaagtaa
     7801 aatagttgat taatatgtgt attatagatt gttttatgaa gattaaatgg catagcaagt
     7861 agtgtgattg gtttatgtta agtatattaa gtgtaaagtg gagaattaaa ttgatacaga
     7921 ttttaaagtt tgagttgata tataaaaagg cttgttttat acttttgtat gaagcaagct
     7981 ttttatttta aattttactt ttttgtttaa tattttgtta gtttatgtga taatttttta
     8041 aaagagtaaa agagtaaaag agtaaaagag taaaagagta aaagagtaaa agagtaaaag
     8101 atgttaggtt agaaattttt gacgttataa gaatttaaat tactggatta ttagattact
     8161 aaattactag attattaaat tattaagcta tttaaactgt ttaaattgtt tgaaaaatga
     8221 attgattctt gtagaaaata gttttaaagt ataatttttt ttaacactgt tttattatag
     8281 tacaaacttg tgctaaaata gaatatataa cataatataa gaggtgcata tgaatacgtt
     8341 agatgagaca ttattaaaag aaattataag ttctaataag aagtatacta attatgggca
     8401 agtcgctagt tacataccag aattaaaaaa cgctagaaga aatgatttag gaatttgtat
     8461 catagatagc gaaaataatc tttatagtgc tggaaactgt agcacaaagt ttactataca
     8521 aagtatttca aaaccaattg tgcttgctat ggcacttatg gataatgatt gggaagacgt
     8581 tttttcaaac gttggaatgg agccaagtgg ggacccattt aattcaataa tgaaacttga
     8641 aattaatgac acaaaaaaac cctgtaatcc aatgataaat gcaggggcta tagtaactac
     8701 ttcccttata aatgggagtt gtttagaaga aaaagaagaa agaatgctta gtttctttag
     8761 aaagttagca aaaaatgata atataggaat aaactatgat gtctataagt ctgaaaaaat
     8821 gactggagat agaaacagag ctatggctta cttattgaaa agtgatggat ttatcagagg
     8881 gaatgtagaa gatgttctag acctttattt taaacaatgc tcaattgaga tagattctgt
     8941 agatttagcg agaattggaa taaatcttgc aaattatgga gtagatatag aaaatggtga
     9001 gcatttaatg agtgaaatgg tttctaggat tgtcaagaca tttatgatga cttgtggaat
     9061 gtatgatgct tctggggaat ttgctattaa agttggcatt cctgcaaaat ctggagttgg
     9121 gggtggtata atggcttctg tgccgggacg catggggatt ggtgtttatg gacctgcgct
     9181 tgacaaaaaa ggtaacagcg tcgcaggagt taaagtttta gaggagttgt caaataaact
     9241 caaattaaat attttttaaa atattaagaa aggatttttt tgacaacaac atataattta
     9301 atatataatt aaattgtaaa gaaatatgaa ttaaataaat tttttaggag gggtcaatga
     9361 aagaggtatt ggtattacga gatttggagt gcataaaggc tattgcgcat ccacgtagaa
     9421 tagatattct aaaagcattt gacaaatcgc cattgtcagc aaaacaatta tctcaattat
     9481 tggaagaacc tcatgcaaaa ataaactacc atataaaaat gttatacaaa gttggtattt
     9541 tagaattagt tgaggaaaaa ataaagtcgg ggattgtgga aaagtactat tatccaagtg
     9601 caaaaaatgt ggttataggg aataggatac ttaatttttc tttagacaat ggggaagaaa
     9661 aagaagaatt gtacatatca aaatttgaaa atatgagtga agttttttat aaggcagcag
     9721 aggaagatgt tttagaaaat gaaaatatag ttgattatca tgatatttct cttactcatg
     9781 atgaattagt tgaacttagt gacactatga agtcaaagat agatgaaatt ttaaataaaa
     9841 gacaacacaa tgttgaaggt tctaagtatg atatagctat ggttatagtt cctactcttg
     9901 aggaggaatg tcctagttag agaattaatt atggattaat taaagatata atattagaga
     9961 ttgaacatca aaatttactt aataatcaaa aaatagtttt tggtatgggt aaaacaatga
    10021 tttttaatct ctattttttt gttttcttat acacctattg tatttgtaaa taatatgtat
    10081 agtgtaagat gtatacacta tctgagaagt gcttagataa tatacaaagt atgtaagatt
    10141 ataatatttg aaattgatta aaatgggtat aattaaagtg taaatattaa aattaaaaat
    10201 taatataaat taaatcaatg ctagaaatat gttaaaagag gaatgagatt agttgggata
    10261 gaacatccct tagagcttat gaatttttag tgaaaaagta ctatcaaata ggaatctcca
    10321 tcttcatatg ttggctaaat atagttaagg tggagtagtt caaaattaaa attgagtaca
    10381 agtcgtagta caaataaaag gagattaata tgattaaatt aggaacacat ctttcaatag
    10441 caaaaggatt tgctaatgcg gctgagacag ctgtatatat tggtgcaaat acatttcaat
    10501 tttttagtag aaatccaaga ggaggaaatg ctaaagaatt tgatgaaaaa gatataatta
    10561 aatttcaaga aattagaaaa gaaaataatt ttgcgccact gcttgcacat gcaccatata
    10621 ctatgaatct gggtggtaca aaggatgatg tatacgaatt tgcaacaagg gtgatagatg
    10681 aggatataag aaggatggac tcattaggaa ttgaatacat gtgttttcat cctggaagtc
    10741 atataggtgg tggtgtagat tttggtatag atagaatagt aaaaggattg aacaatgcca
    10801 taaagggtga tgaaaatata actatacttc ttgaaactat gtcgggaaag ggaactgaaa
    10861 taggttttaa atttgagcaa ttaaaaagta taatagacaa aattgagcat aaagaaaaaa
    10921 taggtgtgtg tcttgataca tgtcatattt tttcagccgg ttatgatata gtgaatgatt
    10981 tagatggggt tttggaagaa tttgataagg ttataggcat agaaagattg aaaactgtcc
    11041 atctaaatga tagtatgatg ccatttggag acaaaaaaga cagacatgct cctatagggg
    11101 aaggaaagat aggattaaaa gcattaattg attttatgga acatcctagt ctaaaacatt
    11161 taccattttt cttggaaact ccttttgatg atgaaggtca caagagagag cttaaaatga
    11221 taaaagaaat actatctagt aaataaacct ttattaaaaa tatgtgaaat actctgccct
    11281 caacataatt agggtggaga tacaatcatg aaatgtgata atttaaatta atggatagga
    11341 ataacaaaaa ttgtatacaa attaactggg tataaagtat gattatatta tgaatagact
    11401 gatataaaat ataattatat tatgaatagt atgtaaatat attgcaaaga ttctcataat
    11461 ttgttgtata attaaaggtg acatatttat attatataaa aaattattaa aagttaggtg
    11521 gggaaagata tgagaaattt aggcaatact aacatgaaaa taaagagagt tggctttggg
    11581 ggcattccaa tacaaaggat tactcaagat gatactaact tagttataaa tgagttagaa
    11641 aaacaaggaa taaactttat tgacagtgca agagggtata caataagtga ggaagcaatc
    11701 ggaattgcca ttgaaggaaa aagagataaa tttttcttag ctactaaaag tatgtccaga
    11761 gattatgatt caatgaagag agatgttgaa ataagtttaa ataattttaa aactgatttt
    11821 atagatttat atcaattcca taatgttaaa gaagaggagt atgataatct ttttaaagat
    11881 aaaatggctt atagtgccct tttagaggca aaggagcaag gtaagataaa acatattggt
    11941 ataactagtc acaatttaaa tactatagaa aaagctatag aagatggaaa atttgacact
    12001 atacaattcc cttacaatat agttgaagga caagcagatg aagtgtttaa aaaagctcat
    12061 gaaaaaggaa ttgggataat agtaatgaaa cctttagctg gaggtgcttt agacaatgca
    12121 acactggcta ttaaatatat actatctaaa gattacatag atgtagttat accaggtatg
    12181 gagagtgttg aacaggttag acaaaatgtc gctgtacttg aaaatcttgt gctagatgaa
    12241 aaagataata aggaaattga agaaataaga aattctttag gtaaaaaatt ctgtagaaga
    12301 tgtgaatatt gtatgccttg tgctgtagga ataaatatac cattgagttt tttatgtgaa
    12361 ggttattata ctagatatgg attaaaagag tgggctaaag aaaaatatga ggttatggat
    12421 gttaaaccta ctgagtgtat tgactgtggg ctttgcgaga gtagatgtcc atatgaactt
    12481 cctataagag aaatgcttaa gactgttgtt gaaaagctag gatagatttt atttattgaa
    12541 atcggtgtat taaatttact ccgatttctt tttattagat gtggtcttat atacaaatat
    12601 taaatttaca tagttatagc tattatataa atttaatatt tgtttaatac ttattaaata
    12661 tttgcttaat gctttttaaa aacatttgtt tgagtataga cataacacaa ttattattgt
    12721 tgtattagta tagtttcaaa tactggagta tcaatataat gtcgaataac acataaaatc
    12781 tttatttttc aaaaatatta taggatatat cgtatttaga tactggataa agttcaattt
    12841 caaccctagg gttatcttta tctataaaat caaataaaaa tactggctta agttgtttat
    12901 cattttttat tattccactt ttttcaatac catcacaaat actttttgga taattatgta
    12961 aatcccccat tctcttattt gggaagaata atttcaagac tgttattaga ttttcttcaa
    13021 cagtttcccc ttgatactgt tggtttataa aacctgcaat catgttttcg tatgcaagat
    13081 acttagaata ttttcccttt gaaggcatcc atgcttgacc atttatgtta tgaagcttaa
    13141 aattagattt actaataggt ctacctggaa ttgttatttt aatcaaattt ttcaccatcc
    13201 ttatacagta tttattataa tctgtatatg atttaaaagc aaattgttat ttaaagtgtt
    13261 tttacagggc ttgtttgtaa aattttccac tttagatgta gtaatataag ataagtattt
    13321 tgcttacaaa ttttaaaatt tgatatatga tggacatatt catattagac tattataaga
    13381 ccttcataat attaataagt ataagtttag taaagagagt aaaaagaaat ccatataagc
    13441 caagtaaaga cttaataaat ggcaatgtaa atgggatatt aattataaga aaaaatcaat
    13501 ctttttgcat taactatagg aagaatgtca aaatataact aatgatattt gaagttttag
    13561 agtttatatt aaaaggtaag aaggttaagt gggtaaaaaa ggttgaatag attaaaaagg
    13621 ctaagtatct aaaagagtta agtaggtaaa aaagttaaat aagtaaatga aaaagacgaa
    13681 gtatctaaaa gagttagtaa ataaaaaagt taaataagta aataaaaaag atgaagtatc
    13741 taaaagagtt agtaggtaaa aaactaaata ggtaaaaaga cgaagtatct aaaagagtta
    13801 gtaggtaaaa aaattaaata gataaaaaga cgaagtatct aaaagattta agtaggtaaa
    13861 aaaattgaat agctaaaaag attaagtatt taaaagagtt ataaaaaagt taaataaata
    13921 aaaaagacga agtatttaaa agagttagta gctagaaaag gttaaaaaaa ctaaaaaaat
    13981 taaataaatt taaaaagtca attagattaa aaaggaataa ttttatggat aataaggaat
    14041 taaaagcatt ttgtaattta ataggattaa actgtgtagg agtagcaggg gtagataagt
    14101 atgataattt agaaaagata cttaaggaca gacaacaaaa aggttattta actggtatgg
    14161 aagaaccaat aattgagaac agaattaacc caagacatat aatgaaggat gctaactcta
    14221 taatagtctg tgcatttcca tatcatataa atagacaaga aaagaataaa aattcaaatt
    14281 tatcaaaata ttgtcatgga aaggattatc acattgtagt aaaggacttt ttacaacaaa
    14341 tttgcgatta tatttctaaa acagtaacag attttaaata caagttattt gctgataatg
    14401 gaccattagt tgacaggtat ttagcttatt tatcaggaat aggatatttt ggaataaata
    14461 ataatatcat aactgatgaa tatggttctt acgtatttat agggtatata gtaaataatt
    14521 ataaatttga agaagataaa ccactagaaa aaagttgttt taaatgtggt aagtgtgtaa
    14581 aatattgtcc gggaaatgct atattgggaa attatgatat gaacccccaa aaatgtttat
    14641 catatataac tcaaaaaaaa ggagatttgt cagagaaaga aaaagttgtt ttaaagaatg
    14701 gcaaaaaggt atttggatgc gatatttgtc aagaagtatg tccacataat gttgaaatat
    14761 caacaactca tattttggaa tttaaagaaa atataataga ttatttggat tatgatgaga
    14821 tacaaaatat ttcaaataaa gaatttaaaa ggagatatgg agatagagct tttagctgga
    14881 gagggagaaa tataataaag agaaatatgg aaataatttt agataagtat gatgactaat
    14941 aataagagtc tgtttcatat actttaatgt gtatttactt taacacttgt tgtataaaag
    15001 tcatattata tcattaaagt taaatatggg gaggaggggg aatattgaaa tataataata
    15061 catctgaaat aaatccacta gattatatat tgggtcaaga aagagctgta gaagctatgg
    15121 aattagggtt gaaaataaat aatccagcgt acaacatata tatagctggt gaacctggaa
    15181 ctggtaaaag tacttatgcc ttaaaggttt taaatgaata tgcatccaaa aaaaatacgc
    15241 ataaagattg gtgttatata tataattttg aaaaccctag agagcctatt atagttgaat
    15301 tagaaaaggg gtttggaaga gaacttaaga aagatatgga gaaattaatt gaaagtcttt
    15361 tagaagattt taaaaatgcg tttgaaagtg aaaattttga aatagaaaaa aataaacttc
    15421 tggatgaata tgaaatagaa aaagatatgc ttttgaagca aattaagaaa tatggagaag
    15481 aaaaaggatt taaattaaaa cagagtaaaa tgggaatagt ttttatccct ttgaaagaag
    15541 aggaagatga aagtgatgag tctgatgaag agttttacaa agctaaaaga gaactagaaa
    15601 atatggcgat acaggtcgta tataaaatta gaaacttaga agaaatagct gaaaaagcag
    15661 tgttagagct tgaagaagag atagctaaac ttgtagtaga acctcacatc aagagattgt
    15721 gtgaaaaata tgaaaattat gataagattc aaacttatct ggaaaatata aagaaagata
    15781 taatagaata tatgtatttg ttctatttag atgaagagga gttaaaagat aagtatgata
    15841 aagagcattt tattaaatac aaaattaacc tatttgtaga caatggaagc tcaaagaata
    15901 aagaatcagc acctgttgta gtagagataa acccaagtcc agcaaatcta tttggaaagg
    15961 cagagtatga ttatgcaaat ggaaatataa agactgattt cacaaaacta ttatcaggag
    16021 catttcatag ggctaatggt ggttatttag tactttatgc agaccaatta ctaaaatata
    16081 caatgtcttg ggaaattctt aaaaagactt tgcagactaa aaaagtaata ttggaaacac
    16141 aaacagcaat taaaccagaa aatatgccat tggatgttaa attagtactg attggaagcc
    16201 actatatata tgatatttta tatagatatg atgaagattt tgaaaaatat tttaaagtat
    16261 ttgtagactt tgatagtgaa atggataaaa atgaagataa tgaagaagga atagcaagat
    16321 ttatagcata ccaatgtgat aagaataatt taaggcattt tactaaatca gcagttgaag
    16381 aggttattaa atttagcact agattatctg gtgatttaga aaaactatca actaagttta
    16441 ataaaataat ggaagttgta atagaaggaa gtgcttatgc agagtttaga aattcggagt
    16501 atacagagca gtgtgatgtt aaaaaagcaa taagtgaaaa gagaaaaaga atcaatagag
    16561 tggaaacaca tatggatgaa tcaattgaaa atggatttac tctaatagaa acagagggac
    16621 gaaaagtagg agtgataaat ggtctgtcag tcttaagtac aggagaatac tcttttggta
    16681 gagcttcaag gattacagcg accactagcc caggaagtaa aggcatagta aatatagaaa
    16741 gagaagtaaa tatgagtggc tctatacata acaaaggagt acttatatta ggtggatatc
    16801 tttctgagaa ttttgcacag gatttactat tgtcactaaa tgcatatgtt tgttttgaac
    16861 aaaattatgg tggaatagat ggagatagtg catcttctgc agaattatat gtactattat
    16921 catctcttag tggagtatca attaaacaaa atattgctgt tacaggttct ataaatcaaa
    16981 agggtgatat acaagtagtt ggtggtataa gtgaaaagat agaaggattt tattctatat
    17041 gtaaaactaa agggttaaat ggtgagcaag gcgttataat tcctagaaaa aatcaaagaa
    17101 atctcgtttt atcagatgaa gttaatgatg cagtgcgaga tggaaaattt aagatatata
    17161 ctgttgaaag agtagaagag gctatagaga tattgacaga tgttaaattt gaagaaataa
    17221 agaaattggt aaaagaaaaa ttaatatctt tcagcaagat acaaactgtg tcaaaagaat
    17281 aagtttatta tagaatttaa tgggtattta tgtataataa aaagcaagaa ctttaatagg
    17341 tttttgcttt ttttgtaaat atatataaat taaattctta tttatatgtt ttatatattg
    17401 atgtttattt tttgttgata tgattaaact atttataaat agcgttttat aaattggtat
    17461 tttgaagggg gataattatg aaaaatgtaa atctaaaaga gataaatgaa aaagatgtaa
    17521 ttgtggaaga agagataaat aaaaaaggaa tggataagaa agatataatt gtagaagaag
    17581 agataaataa aaaaggaatg gataagaaaa atataattga gaaggaagag ataaataaaa
    17641 aaggaataga taagaaagat ataattgaga agaaagagat aaataaaaaa ggaatggata
    17701 agaaagatat aattgagaag gaagagataa ataaaaaagg aatgaataag aaagatataa
    17761 ttgagaagga agagataaat gaaaaagaaa tagataaaat gattagtgaa aaagatgaga
    17821 taattgatga gaaagatata gagaatttta ggtatattga agaagataaa aaaagtatca
    17881 aagtaagtaa aaaaagtact aaaaaaggtg aaacggagaa aaaaacaaag aaaagtagtt
    17941 ctagtaaggc tacacaaaaa caaagcaaag aagttaaaag taagtctaaa attaaaaatg
    18001 aatcagccaa taaaaaagat gtaaataaga ttttagatga gttggaaaaa ttgtacccag
    18061 atgctaaatg tgagttaaat tatgggacag cctttgaact tttaatagca actattttat
    18121 cagcacaatg tactgatgta agagtgaata aagttacttc agagttgttt aaaaagtaca
    18181 acacagctag agactttgct aatttgagca ttgaagaaat tagtaaagag ataaagagtt
    18241 gtggtcttta caaaagcaag tctcaaaaaa taaaggatac atctgaacag ctatgtgaat
    18301 tatatgatgg tgaagtacct gatagcttag aaaagcttat aaaattacct ggtgttggaa
    18361 gaaaaacggc aggggttgta cttagtaacg cttttaatca tccagcaata gctgtagata
    18421 ctcatgtatt tagagttagc aatagaatag gaatagtgga cgagccaaat cctcaaaaaa
    18481 cagaatttgc acttatggaa gctataccaa aagaaagatg gtcgcactca catcatgtat
    18541 taatttttca tggaagaaga atgtgtaaag ctagaaatcc agaatgtgca agttgcccaa
    18601 taaaagaaga ttgtaattat tataaagaac ttaatgaaac gaaataactt ttagaaagta
    18661 agttgtacaa gagggatttt ctgatataat aatacttgtg aaaatgttag ataaaaaact
    18721 attatata
//
LOCUS       DACTZW010000083        18607 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.083, whole genome shotgun sequence.
ACCESSION   DACTZW010000083 DACTZW010000000
VERSION     DACTZW010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18607
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.083"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(253..1032)
                     /locus_tag="JAM15_15045"
     CDS             complement(253..1032)
                     /locus_tag="JAM15_15045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HAT6799568.1"
                     /translation="MLTRIIASLALVPLFLFVVYGGIPLYIAETAIVYIALHEFYKAF
                     KIKDVHPIFIIGYLFSIYLAVKNIFNLPLEYIYAVIFILFLASIIYMLMGKNNVIDVS
                     ITFLGIFYIGVFLDFIIITINGFEKGSIYVWLIFVISFMTDIFAYFSGYLLGKHKLIP
                     KVSPKKTIEGAIGGIIGSTLCCILFGYLFGIDLLQLAIIGSIGSVIAQLGDLFASSIK
                     RYVGIKDYGKIIPGHGGILDRFDSVILVAPFVYSAIKFFIR"
     gene            complement(1045..1779)
                     /locus_tag="JAM15_15050"
     CDS             complement(1045..1779)
                     /locus_tag="JAM15_15050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HAT6799569.1"
                     /translation="MNNNIIYDIDLNNIPTHIAIIMDGNGRWAKARFLPRTAGHKAGV
                     ETIRDIVKECSKLGVKHLTLYAFSTENWKRPKLEVDTLMNLLSTYLRNEIAELHQNNV
                     KVTAIGDISALPKTCIRELNSAKELTKNNTGVNLNLALNYGSRADIKNALIDIVKNCE
                     SGKIDINNIDEDIIKNYLSTKSIPDPDLVIRTSGEQRLSNFLLWEVAYSEFYFTDIHW
                     PDFKKEELQKAIYVYQRRDRRFGGLK"
     gene            complement(1808..2011)
                     /locus_tag="JAM15_15055"
     CDS             complement(1808..2011)
                     /locus_tag="JAM15_15055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799570.1"
                     /translation="MKKYYNLLGLHVDEVKQYFDEQNINYTIKSIEGKKDKEKLVVPR
                     VIKISEIGDSVELIITYFSDSLV"
     gene            complement(2014..2571)
                     /gene="frr"
                     /locus_tag="JAM15_15060"
     CDS             complement(2014..2571)
                     /gene="frr"
                     /locus_tag="JAM15_15060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002844086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HAT6799571.1"
                     /translation="MKLEIHKQLEEKMNGTIDALKFEFGTIRAGRANAQMLDKIRVDY
                     YGTPTPINQIGAISVPEPRILMISPWDKSAMHEIEKAIANSDLGLNPSNDGEVIRLSV
                     PALTEERRKELAKKASKAAEEFKVRIRNERRDANEKIKKMEKGGELTEDELKKAQDEV
                     QKMTDKFIKEIDTLLSKKEKDIMEV"
     gene            complement(2597..3301)
                     /locus_tag="JAM15_15065"
     CDS             complement(2597..3301)
                     /locus_tag="JAM15_15065"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HAT6799572.1"
                     /translation="MDKPIYKRVLLKLSGEALAGERGFGINNDVVNDIAIAIKKIQEI
                     GVEVAVVVGGGNFWRGRTSEGMDRTTADYIGMLATVMNAMALQDALENIDVATRVQTA
                     IDMRQIAEPYIRRRAVRHLEKERVVIFGAGTGNPYFTTDTTAALRAAEMEAEVILLAK
                     NVDAVYDKDPKVHADAKKFTELSYMEVIQKELKVMDSTATSLCMDNKIPIKVFELTTE
                     NIIRAVKGENIGTTVK"
     gene            complement(3386..4297)
                     /locus_tag="JAM15_15070"
     CDS             complement(3386..4297)
                     /locus_tag="JAM15_15070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HAT6799573.1"
                     /translation="MANITAQMVKELRESTGAGMMDCKKALQEAEGNMEKAVDLLREK
                     GLSKAAKKAGRVAAEGLVAIEMNDDNTVASMVEVNSETDFVAKNEDFKVFVKDAACMA
                     LATDKEDIASLLGETHKEGITLQEVLNNRVAKIGEKLDFRRFAKVVTNGQVAGYIHGG
                     GKIGVLVEMETEARDAKVLELGKDVAMQVAAMNPKYVSRDEVDAEYIAHETEVLTQQA
                     LNEGKPANIVEKMVKGRLEKELKEVCLLEQTFVKNPDITVKQLVADVAKAVGSDIKVV
                     KVVRFEVGEGIQKREENFAEEVAKQLK"
     gene            complement(4376..5089)
                     /gene="rpsB"
                     /locus_tag="JAM15_15075"
     CDS             complement(4376..5089)
                     /gene="rpsB"
                     /locus_tag="JAM15_15075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002844082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HAT6799574.1"
                     /translation="MSVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIYIIDLQ
                     KTVKKVEEAYKFTKEVAETGKPILFVGTKKQAQDAIKDEAERCGMYFVNERWLGGMLT
                     NHKTIKTRINKLRELEKMEEEGVFNVLPKKEVIKLRAEKEKLEKYLGGIKDMPELPGA
                     MFVVDPRKENIAIQEAHRLGIPVVGIVDTNCDPEQLDFAIPGNDDAIRAVKLITGAMA
                     TAVIEGRQGAEEEVAEDQE"
     gene            complement(5296..6480)
                     /locus_tag="JAM15_15080"
     CDS             complement(5296..6480)
                     /locus_tag="JAM15_15080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HAT6799575.1"
                     /translation="MKNALKKIISLAMILVFIIPNYSYADGKSVDKYSKTSILIDQET
                     GRVLYSKEPDMKVPLASLSKMMTFLLAIEAIENKEVKETDKVKIDKSIASVKGSSYKL
                     KDGEEVPLIELMRGLMIVSGNDAAIAIAKHICKTKEAFVDRMNKKAKEIGMSNTHFLN
                     PNGLPIYDLSNPKKPAKENISTAKDIAILGKYMFDHYEKQVTAITDMETYTNSDRSFE
                     KSNTNALLRIIPEVDGIKTGYTGNAGYCLSFSMVVNKNEKNEKKRRVIGVVLGTNHKN
                     KRTSASLALLKYGKENFNMKKVIDKDSFIGKKYIKGMKELEVTLKAKDELYTILKDDE
                     SIKSEVKIKNIEYPVKKGDTMGIIKYYTSSGDLLGSVDIVSNNSIDNVSLKTKLKMKF
                     AN"
     gene            complement(6584..7642)
                     /locus_tag="JAM15_15085"
     CDS             complement(6584..7642)
                     /locus_tag="JAM15_15085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HAT6799576.1"
                     /translation="MNCKWISKIDERKKCHREADSSGCCIFHKENKSDEEIQLMMDTI
                     HKEEISEFNGFVFENEFNAEEILTYNYKILDFSESIFKQKANFKKYIFKKNIIFNYTE
                     FRDKVLFNGCIFLENCDFNRTIFSKNYINDRIFEKVKFKGPDLVVNKVENFPRMDGII
                     FSMCTKFVLKNVEYGKSEYEHGKINYRIARNQATKIGEYEMIGFYYYKERIYSSKIMK
                     RSNYPTFSDYLVEKFFDQIARYTTGYGEKPWNILLVIIAIISVFALLYLFVGIESSNS
                     TLVALDINNIGDYSLSEIFKMYMDLWYFSMATFSTVGYGDMVATSLIGKALAGIEVFF
                     GVTIGAIWASVIIKRMIR"
     gene            complement(7856..8500)
                     /locus_tag="JAM15_15090"
     CDS             complement(7856..8500)
                     /locus_tag="JAM15_15090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAT6799577.1"
                     /translation="MEQHNKVGNFGDLLKVLLDEKELSMGELSKKSGIDKSTISRIAN
                     NKQRPNINHLEKMAIHLNINLEELLKASGYEFRNSNNQIFNADSDFSNFDDILGFANL
                     INDKNFNGNIEKELSKCKLYVQTDEGKKLLFDNFNKKIDSIEKQGQFTDRLRQMYADF
                     CTDGLTIKKYLLIGSMLLYFVISTDVIPDFVFPIGFMDDLVALNIVTKLLKNDK"
     gene            8685..9308
                     /gene="ytaF"
                     /locus_tag="JAM15_15095"
     CDS             8685..9308
                     /gene="ytaF"
                     /locus_tag="JAM15_15095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation membrane protein YtaF"
                     /protein_id="HAT6799578.1"
                     /translation="MIESILLVTSLCIDAFVTSFGYGVNKVKVPLYSNIIISVVCSAI
                     LAISLFAGTIVRDFLPQNITMLICFFILFLLGSARLIESFFKSYFKKKSIHSKNYNFN
                     MLDLELNFNVSIEPDVLDTSKSKVLKSAEAFTLALALSLDGLAIGFGSGLVGVNYIQV
                     ILFSLISNIIAVLLGCLLGNMFVKNVNLNLSWLSGLILLIIGFMKIC"
     gene            complement(9371..11281)
                     /locus_tag="JAM15_15100"
     CDS             complement(9371..11281)
                     /locus_tag="JAM15_15100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HAT6799579.1"
                     /translation="MNSNTFERLQLNEVKDLIKIHCVSSLGKNLIDKLTPSGNIGVVR
                     RKLAENKEARKIIENSNHIPLEGLFNAGSTIDKIEKGMIIEPVELVNIEDFLRGCRKM
                     KAFMLEKEFYSPTLSSYALNITECKSIEDEINYCIKSNKVDSNASKELKKIRRNIEIT
                     EGKIKDRLNKFITSTVNKKYIQEFIISKRNDRYVIPIKSSYKNEVNGTILDTSSKGNT
                     VFIEPISVSNLSTELTMLKADETIEEYKILSYLTELIFEKISQIKLNIEILSEYDMVF
                     AKAKYSQKIKGITPKINNNGYIKIIKGKHPLLTRDAVPLDFEIGKNYRSLIITGPNAG
                     GKTVTLKTVGLLTLMVQCGFDISAKEGSEFSVFEKVFVDIGDNQSIENALSTFSSHIK
                     NIAEIMSLSNNSTLVLFDEIGSGTEPNEGAGLAISLLEEFYKMGCITIASTHYGEIKK
                     FATLHPEFENAGMMFDKETLEPLYKLTIGKSEDSNALFISKKMGIKNRVLDRAKEYVI
                     DRNYNLDLVKRSKLQSNIEDKNSSEVILNYTDYNVGDKVKLLDEDDFGIVYKPMDKFN
                     NVEVLFNDNFISVNIKRLQLSIKASELYPEGYDLDVLFTSFKERKLEKDIQRGSKKAL
                     KKIQKEIRENRK"
     gene            complement(11815..12882)
                     /locus_tag="JAM15_15105"
     CDS             complement(11815..12882)
                     /locus_tag="JAM15_15105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA ligase RtcB family protein"
                     /protein_id="HAT6799580.1"
                     /translation="MSNIKIIASNKCWIEDIARKQLEDISKLNGTLRVVGLPDLHTGK
                     IPVGLAVETKNIIYPHIIGNDIGCGMTLFKTGVLKKKFKKDKWIKSLSKIKDLSDIEI
                     KNTYKEECPILNLGTIGSGNHFVEIQCISEIYNKEQFEQLKFSSDDIMMLVHCGSRNY
                     GEDILKKFYDKDGLEVESEKAIDYIKKHDNALMWAERNREAISKKIMQSIGTSGDVET
                     IFSINHNFIEKREDKFIHRKGAVSSERGAVIIPGSRGSLSYIVMPTENTEISLYSLSH
                     GAGRKWSRSVCKSRLKSKYSKDTIKQTKFKSQIICNDVNLLFQEAPEAYKNIEQIIES
                     LIEYELIQVVATMKPLITYKG"
     gene            complement(13128..14102)
                     /locus_tag="JAM15_15110"
     CDS             complement(13128..14102)
                     /locus_tag="JAM15_15110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HAT6799581.1"
                     /translation="MNFIGNRYEVVNSDDVLEINKIYKARDVFYRRNVLIKVIKHNNY
                     ICEDFVSNLIDESTALDEINSPYILKIIDVGIHCTEETTLYYVVSEDFNGIGLDELIL
                     GNYLHLEAIVNIMIQVLKALEMIHRNHSYHGSLKSSSIIVDTEYNIKICDFGITKANN
                     GVNTRSYGNRRYLCPHQLCINYTDKESDFFATGLILFESIFKKLPFGESNSEEKMLQS
                     IDKGLDWNSIKAINGNTELINVIKRLLGRNNKYTRANDIIIDLSKVMYEKAYIEVEDE
                     KEEEQKQDKVIQVKKEYKSKMRKKLHKKLVVAGLAIVMISMIIISSII"
     gene            complement(14382..15641)
                     /locus_tag="JAM15_15115"
     CDS             complement(14382..15641)
                     /locus_tag="JAM15_15115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance protein"
                     /protein_id="HAT6799582.1"
                     /translation="MGRRATRVSRLGKEKKRSVLIVLAALVLIMGGFTYFFNSKFLYN
                     GKIAKNVYIEGVNVSDMTKAEALKAITDKYTPEDLNLTYDGKKYTISPKDIDLKYDTE
                     DVVKDAYESTKKGSYFQNLKKYIDIRVNKANMKIKAEYDEAKLSSKVSSIADSINVKM
                     KNASISVGSGGLSYTDSVVGREFDLAANKESIYNMIKNKEHKTLELKVNLQKPDITTE
                     QVKTVNSVIGQYSTTYSQAVEGRSYNVGLSARKTSDVLLMPGEEFSYNKLTGPSNKAN
                     GYKDAPVIVYGKLEQSAGGGVCQTSSTVYNAALLSGMEITQVTNHSSASTYVPKGRDA
                     TVSDGGLNLKFKNPYKHPVYIKNYAGGGSVSSVIYGNSGDKPNISIEVKQTGQNKYST
                     YRIFKDSSGKVIKKEHISNSSYKELKK"
     gene            complement(15881..16510)
                     /locus_tag="JAM15_15120"
     CDS             complement(15881..16510)
                     /locus_tag="JAM15_15120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease"
                     /protein_id="HAT6799583.1"
                     /translation="MKIVTYNIHKGMDSNNRLTLTKMGLYLKQLDCDVICLQEVLYPQ
                     FLALKAVLNMDGVFATNVKKVNMIYGICTFTTSKMLNSNHFFLTSKKEQRGALCITID
                     AYGRIINVINTHLGLDRQERAKQLDEIIDYRNRLVGIVILCGDFNEKNVFLSMFNDMA
                     ISLNKSYLPTFEKSNSRIDYIFVNKNTELKGYTVEKIYLSDHYPVIGYI"
     gene            complement(17208..18368)
                     /locus_tag="JAM15_15125"
     CDS             complement(17208..18368)
                     /locus_tag="JAM15_15125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HAT6799584.1"
                     /translation="MIETGFVYCSFLVVFVGVIFFMVDKLKWKVFDVINPMLLIYLGS
                     AILGSFGLFAQNEDVGTYQNIITVNFLPLMLVFLLIQCDLRKILKMGPKMLLSFFCAT
                     FTFMLGFVIAFIIFKNSMGADSWKILGAASGSWIGGSSNMIAAANALGVAEEGLSYAI
                     LMGSIGYTVWMSVCLMSVKFGPKFNKWTKCDTSFIDEVTSKLEKENKDNTSPTFVELM
                     ILLSVGFGVASFAQIVSKILPTSGILNETMWVVLVASTVSILLGMTKISKLKGSTLVG
                     NVFMYLLLAATGSKANFFGLSEAPVYIMFGLVVVLVHAISFIGLAKLFKLDLFTCEVG
                     SIANIGGVTTAPMIAGVHNPVLIPVGVLMGLLGNIIGTYCALMVTQILHMLA"
BASE COUNT         5874 a         3228 c         1855 g         7650 t
ORIGIN      
        1 aaatatcgaa attattaaac aaaaaaatat tttttaatga tagttatagt ataaaaaata
       61 tactcactac aaatatagta tactattata aagtaatacc tattcttata caattcccca
      121 aggtcttcta aatttttgaa caatgaaaat agccatgtaa ctaataactg cagaatatct
      181 ctgcatttaa aagttacata gctattttca ttactagcaa ttatagattg ctcttttaaa
      241 tccaaccaat ctttatctaa taaaaaattt aatcgcacta tatacaaaag gtgcaactaa
      301 tataacacta tcaaatctat ctaatatacc cccatgacca ggtattatct ttccataatc
      361 ctttatccct acatatctct ttatagaaga tgcaaataaa tctcctaatt gagctattac
      421 acttcctata cttcctatta tcgctaattg aagcaaatca atgccaaata aatatccaaa
      481 taaaatacaa caaagtgtac ttcctattat tcctccaata gctccttcta tagtcttttt
      541 aggactaact ttaggaatta gcttatgttt tccaagtaaa taaccactaa aatatgcaaa
      601 tatatctgtc ataaaagata tcacaaatat aagccataca tatatactac ctttttcaaa
      661 tccatttata gttataatta taaaatctaa aaatactcct atataaaaaa ttcctaaaaa
      721 cgtaatcgaa acatctataa cattgttttt gcccatcaac atataaatta tacttgctaa
      781 aaataaaata aaaattactg cataaatata ttctaatggt aaattaaaaa tattttttac
      841 agctaaataa atagaaaata aatatcctat aatgaatatt ggatgtacat cttttatttt
      901 aaatgcctta taaaactcat gcaatgcaat ataaactatt gctgtctcag ctatatatag
      961 aggaatacct ccatatacaa caaatagaaa taatggaacc agagctagtg aagcaataat
     1021 tcttgtaagc ataaaataat ctccttactt aagtcctcca aatcttctat cccttctttg
     1081 atatacgtat atagccttct gtagttcttc ttttttaaaa tcaggccaat gtatatcagt
     1141 aaagtaaaac tcagaataag caacttccca aagtaaaaag ttactcaatc tttgttcacc
     1201 acttgttctt attaccaagt ctggatctgg tatagacttt gtgcttaaat agttttttat
     1261 aatatcttca tcaatattgt ttatatctat tttaccactt tcacaatttt ttactatatc
     1321 tataagagca ttttttatat ctgctctact tccgtagttt aatgctaaat ttaagttaac
     1381 tcctgtattg ttttttgtca gttccttagc tgagtttaat tctcttatac aagtttttgg
     1441 taaagcactt atatctccta tagcggttac ttttacattg ttttggtgaa gttcagctat
     1501 ttcatttctt aagtatgtag ataataagtt cataagtgtg tcaacttcaa gtttcggtct
     1561 tttccagttt tctgttgaaa atgcatataa tgttaagtgc ttaacaccta attttgagca
     1621 ttcttttact atatctctta tagtttctac tccagcctta tgtcctgcag ttcttggaag
     1681 aaatctagct tttgcccatc ttccatttcc atccattata atagcaatat gagtaggtat
     1741 gttatttaag tctatatcat atataatgtt gttattcata ttttgcctcc aatattgttc
     1801 tgactcctta aactaaggag tcagaaaagt atgtgattat cagttctaca ctatcaccta
     1861 tctcagatat ttttataact ctaggaacta caagtttttc tttatccttt ttaccttcaa
     1921 tagattttat ggtataattt atattttgct catcaaaata ttgttttacc tcatctacat
     1981 gaagacctaa aaggttataa tattttttca atattatacc tccattatgt ccttttcttt
     2041 tttagataat aatgtatcta tttcttttat aaatttatca gtcatttttt gaacttcatc
     2101 ttgtgctttt tttaattcat cttcagttaa ttctccgcct ttttccatct ttttaatttt
     2161 ctcattggcg tctcttcttt catttcttat tctaacttta aattcttctg cagctttact
     2221 agctttttta gctaattctt ttcttctttc ttctgttaaa gcaggtacag aaagtcttat
     2281 aacctcacca tcatttgatg gatttaatcc taagtctgag ttagctatcg ctttttctat
     2341 ttcatgcata gcagatttat cccaaggaga tatcattaat attcttggtt ctggtacaga
     2401 tatagcacct atttgattta ttggagttgg agttccataa taatcaactc ttattttgtc
     2461 tagcatttgt gcattagctc ttcctgctct tatagttcca aattcaaact ttaaagcatc
     2521 aattgtccca ttcattttct cttctaattg cttatgtatt tccagtttca taattttact
     2581 cctccttcat tcttcattat tttacagtag ttcctatatt ttcgcctttt actgctctta
     2641 ttatattctc tgttgtaagc tcaaatacct ttattggaat tttattatcc atacataaag
     2701 atgtagcagt agaatccatt acttttaatt ctttctgtat aacttccatg taacttaatt
     2761 ctgtaaattt cttagcatct gcatgtactt ttggatcctt gtcatatact gcatcaacat
     2821 ttttagctaa caatataact tctgcttcca tctcagcagc acgtaaagca gcagttgtat
     2881 ctgttgtaaa gtaagggttt cctgttcctg caccaaatat aacaactctt tccttctcta
     2941 agtgtctaac tgctcttctt cttatatatg gttctgcaat ttgtctcatg tctatagcag
     3001 tttgaactct tgtagcaaca tctatatttt ctagtgcatc ctgtagcgcc attgcattca
     3061 taactgtagc taacattcct atatagtcag cagtagttct gtccattcct tcactggttc
     3121 tgcctctcca gaagtttcct ccacctacta ctacagctac ttcaacacct atttcttgta
     3181 ttttttttat agcaatagca atatcattaa ctacatcatt atttatacca aaacctcttt
     3241 ctcctgctaa tgcttctcca cttaatttta acaataccct tttgtatatt ggtttatcca
     3301 tcagaaacct cctatttcaa tccttcatat ccaatttttt ctatttttta aaaaagagaa
     3361 cacctgcgtg ttctctcttt ggttattact taagttgctt agcaacttct tctgcaaagt
     3421 tttcttctct cttttgtata ccttcaccaa cttcgaatct cacaacttta acaactttta
     3481 tatcagaacc tactgcctta gcaacatcag caactaattg tttaacagtt atatctggat
     3541 ttttaacgaa agtttgctct aataaacaaa cctcttttaa ttctttttct aatcttcctt
     3601 taaccatttt ttcaactata ttagctggtt ttccttcatt taaagcttgt tgagttaata
     3661 cttctgtttc atgtgctatg tattcagcat ctacttcatc tcttgaaaca tacttaggat
     3721 tcatagcagc aacttgcata gctacatctt tacctaattc taaaacttta gcatctctag
     3781 cttctgtttc catttcaaca agaacaccta tttttccacc accgtgaatg tatccagcaa
     3841 cttgtccatt agttacaact ttagcaaatc ttctaaagtc taatttctca cctatttttg
     3901 caactctatt atttaaaact tcttgtaaag ttattccctc tttatgagtt tcacctaata
     3961 aagaagctat atcttcttta tcagtagcta atgccataca agcagcatct ttaacgaaca
     4021 ctttgaagtc ttcgttttta gcaacgaaat ctgtctctga gttaacttct accatagaag
     4081 caactgtatt atcatcattc atttctattg caactagacc ttcagcagca actctaccag
     4141 cttttttagc agcttttgat aatccttttt ctcttaataa atctactgct ttttccatgt
     4201 ttccttcagc ttcttgtaaa gctttcttgc agtccatcat tcctgcgcct gtactttctc
     4261 ttaactcttt taccatttga gcagttatat tagccatttt ttaagtttcc tcctacttat
     4321 tctattccat attataaatg gtaagggcga cccttaccat ttaattgtca aattattatt
     4381 cttggtcttc agctacttct tcctcagcac cttgtctacc ttcaattaca gctgttgcca
     4441 tagcaccagt tattaatttt acggctctta tagcgtcatc atttcctggt atagcaaagt
     4501 ctaattgttc tgggtcacag ttagtatcaa ctataccaac tactggtata cctaatctat
     4561 gagcttcttg aatagctatg ttttcttttc ttgggtcaac tacgaacatt gcacctggta
     4621 attcaggcat gtcttttatt ccacctaagt atttttctag tttttctttt tcagctctta
     4681 attttataac ttctttttta ggaagaacat taaatacgcc ttcttcttcc attttttcta
     4741 attctcttaa tttatttatt cttgttttta tagttttgtg gtttgttaac attccaccta
     4801 accatctttc attaacaaag tacattccac atctttcagc ttcatctttt atcgcatctt
     4861 gagcttgttt tttagttcct acgaataaga ttggctttcc tgtttcagct acttctttag
     4921 tgaacttgta agcttcttca acttttttaa ctgttttttg taagtcgatt atatatattc
     4981 catttctctc tgtgaatata tacttagcca ttttagggtt ccatcttctt gtttggtgac
     5041 caaagtgaac acctgcttct aataattgtt tcattgatat tactgacata tcttacctcc
     5101 tggttttata cctccagctt gatcttctcc ctaaaaaacc atgtaatagg caccttttaa
     5161 ggatcccaat gctgtgtgtg atttatttta ttttttcacc tctagtagta tatcacagag
     5221 gtgaagaaat aacaatattt tttccatatt ttctattttt atattttttt gtgtatttta
     5281 taccattttt tgaatttaat ttgcaaattt catttttaat tttgttttta atgatacgtt
     5341 atctatacta ttattactta ctatatctac acttccaagt aagtcacctg aactagtata
     5401 atattttata atacccatag tatcaccttt tttaacaggg tactctatat ttttaatctt
     5461 aacttctgat tttatacttt catcatcttt taatattgta taaagttcat cttttgcttt
     5521 taatgtaacc tctaactctt tcattccttt tatatatttc ttaccaataa agctatcttt
     5581 atcaattact tttttcatat tgaaattttc ttttccatat ttcagtagag ctaatgaagc
     5641 agaagttctt ttatttttat ggttagtacc taatacaacc cctattactc tacgtttttt
     5701 ctcatttttc tcatttttat ttacaaccat agaaaatgat aagcaatatc cagcattgcc
     5761 agtatatcca gtttttatac catctacttc tggtataatt cttaataatg catttgtatt
     5821 gcttttttca aaacttctat ctgaatttgt atatgtctcc atatcagtta tagctgttac
     5881 ttgtttttca taatggtcaa acatgtattt tccaagaata gctatatctt ttgcagtaga
     5941 gatattttct tttgctggtt ttttggggtt gcttaaatcg tatattggaa gaccatttgg
     6001 atttagaaaa tgtgtattac tcattcctat ttcttttgct tttttattca ttctatctac
     6061 aaatgcttct ttcgttttac aaatatgttt tgctatagca attgccgcat catttcctga
     6121 tacaatcata agacctctca taagctctat aagtggcact tcttcaccat ctttaagttt
     6181 ataacttgac ccttttactg atgcaataga tttgtctatt tttaccttat cagtttcttt
     6241 tacttcttta ttttcaatag cttctattgc aagtaaaaaa gtcatcatct tacttaaact
     6301 agctaatggt accttcatat caggttcttt actatataaa actctacctg tttcttggtc
     6361 tataagtata gatgtttttg aatacttgtc tacagattta ccatctgcat atgaataatt
     6421 tggtattata aaaactagaa tcatggctaa tgatataatt ttttttagtg catttttcaa
     6481 atttttcacc ttcttggatt attaagtata tttatattta aattttccct atttagtcca
     6541 atttatatct agtaattaat acctatccat atttacacaa atattacctt atcattcttt
     6601 taataatcac agatgcccaa attgctccta ttgtaactcc aaaaaatact tctatacctg
     6661 ccaatgcttt cccaatcaaa cttgtagcaa ccatatctcc atatcctact gtactaaatg
     6721 tagccatgct aaaataccat aaatccatat acattttgaa aatctcactt agtgagtaat
     6781 cacctatatt gtttatatct aaagctacaa gtgtgctatt tgaactttct atgcctacaa
     6841 ataagtataa taaagcaaaa acacttatta ttgctataat cactaataat atattccatg
     6901 gcttttctcc ataacctgtt gtgtaacgtg ctatttggtc aaaaaatttt tcaactaaat
     6961 aatcactgaa agtaggataa ttagaacgtt tcattatttt actactataa attctttcct
     7021 tataatagta aaatcctatc atctcatatt ctccaatttt tgttgcttga tttctagcta
     7081 ttctataatt tatcttgcca tgctcatact cactttttcc atattcaaca ttctttaaca
     7141 caaattttgt acacatgcta aaaattattc catccattcg tggaaaattt tctactttat
     7201 taactaccaa atcaggtcct ttaaatttca ctttttcaaa tatacggtca tttatatagt
     7261 ttttactaaa tatggttcta ttaaaatcac agttttctaa gaatatacaa ccattaaata
     7321 aaactttatc tctaaattct gtatagttaa aaataatatt ctttttaaaa atatattttt
     7381 taaaatttgc tttttgttta aatatggatt cagaaaaatc cagtatttta taattgtaag
     7441 ttaatatttc ttccgcatta aattcatttt caaaaacaaa tccattaaat tcacttatct
     7501 cttctttatg aatagtatcc atcatcaact gtatctcttc atcagactta ttttctttat
     7561 gaaagataca acatccagaa gaatctgctt ctctatgaca tttttttctc tcatctattt
     7621 tagatatcca tttacaattc ataaatatat atcctccaat acaaaacaat tattactatt
     7681 ttgtattagt ttggatatta ttttatttta tatacttaaa tagttacaaa atatatatta
     7741 gattcttagt tttaaatttt taatctactt cattgtgctt ttaatttgtt tcatataaaa
     7801 aataataaat tttatatact ttgatttatt tatatattaa atatgattct aaaacttact
     7861 tatcattttt aagtaatttt gtaactatat ttaatgctac taaatcatcc ataaatccta
     7921 ttgggaacac gaagtctgga atcacatctg ttgatataac aaagtaaagt agcatacttc
     7981 caatcaataa atatttcttt attgtaagtc catctgtaca aaaatcagca tacatttgtc
     8041 ttaatctatc tgtaaattga ccttgttttt caatagaatc tattttttta ttaaaattat
     8101 caaaaagtaa ttttttacct tcatctgttt ggacatataa cttacactta cttaactctt
     8161 tttcaatatt tccattaaag ttcttatcat tgattaaatt tgcaaatcca agaatatcat
     8221 caaagttact aaaatcacta tctgcattaa atatttgatt attgctgttt ctaaattcat
     8281 atcctgaagc tttcaacagt tcttctaggt taatatttaa atgtattgcc atcttttcta
     8341 aatgatttat atttggcctt tgtttattat tagctatacg agatatagta gatttatcaa
     8401 ttccactttt tttacttagt tctcccattg ataattcttt ttcatctaat aaaactttca
     8461 acaaatcacc gaaattccca accttattat gttgttccat tattttcacc tgctttatta
     8521 tgattggttt tatattatat gatatgattc ttttgttatt taggtgttgt atgatgttga
     8581 aattttatca acaatttatt ggattatctg taacaattta tccattttta caatactata
     8641 actaatataa gtacaaaatt taagagaaag gatgttaatc tactgtgatt gaatcaattt
     8701 tattagttac ttctctttgt atagatgcct ttgtgacaag ctttggatat ggcgtaaata
     8761 aagttaaagt tcccttatat tcaaatataa ttatcagcgt agtttgttca gctattttag
     8821 caatatcgct ttttgcaggt acaatagtta gagatttttt acctcaaaat ataacaatgt
     8881 taatatgttt ctttatttta tttttattag gaagtgctag actaattgaa agttttttta
     8941 aatcttattt taagaaaaaa tctatacact caaagaatta taattttaat atgttagacc
     9001 ttgaattaaa ttttaatgta agtatcgaac ctgatgtctt agatacaagt aaatctaaag
     9061 tgcttaaatc tgctgaagca tttacacttg cacttgcttt aagtttagat ggattagcta
     9121 tcggttttgg tagtggcctt gtaggtgtga attatataca agttattcta ttttctttaa
     9181 tatcaaatat aattgcagta ttacttggtt gtttactagg aaatatgttt gttaaaaacg
     9241 taaatttaaa cttatcttgg ttaagtggtt taatcttgtt aatcattgga tttatgaaga
     9301 tatgttaata agaaagcaat ctaaagataa acttttctct ttggattgct ttcttttgtg
     9361 ctttttatat ttattttcta ttctctctaa tttctttctg aatcttttta agagcttttt
     9421 ttgaacctct ttgaatatct ttttctaatt ttctttcttt aaaactagta aataatacat
     9481 ctaaatcata cccttctgga tacaattctg atgcttttat gctaagttgt aatcttttta
     9541 tatttactga aataaaatta tcattaaaca atacttctac attattaaac ttgtccatag
     9601 gcttatatac aattccaaaa tcatcttcat ctagtaattt taccttatcc cctacattat
     9661 aatctgtata gtttaaaatg acttcagaac tatttttatc ttcaatatta gattgtagct
     9721 tacttctttt aactaaatct aaattgtagt ttctatcaat tacatattct ttagctctat
     9781 ctaaaactct attttttatt cccatttttt tagaaataaa aagagcatta ctatcttcag
     9841 attttccaat agttaactta tacaatggtt ctaacgtttc tttatcaaac atcataccag
     9901 cattttcaaa ttctggatgc aatgtagcaa acttttttat ctctccataa tgagttgatg
     9961 ctatagttat acatcccatt ttgtaaaact cttctaataa tgatattgct aaaccagctc
    10021 cttcattagg ttcagttcca cttcctattt catcaaacag aacaagagta gaattatttg
    10081 ataaactcat aatctctgca atatttttta tatgtgatga aaaagtactt aaggcatttt
    10141 caatactttg attatcccct atatctacaa aaactttttc aaatacacta aattcactac
    10201 cttcttttgc agaaatatca aatccacatt gaaccattaa agttagtaaa ccaacagtct
    10261 taagggttac agtttttcct cctgcattag gacctgttat tataagactt ctataatttt
    10321 tgcctatttc aaaatctaaa ggtactgcat ctcttgttag aagtggatgt ttacctttaa
    10381 ttatttttat atagccatta ttatttattt ttggagtaat tccttttatt ttttgactat
    10441 acttagcttt tgcaaatacc atatcgtatt ctgaaagtat ctctatattt aattttatct
    10501 gacttatctt ctcaaatata agttctgtta aataagataa tattttgtat tcttcaatag
    10561 tttcatcagc ttttagcata gttaactctg tacttaaatt tgaaacacta ataggttcaa
    10621 taaatacagt atttcctttt gatgatgtat ctaatatagt accattaact tcatttttat
    10681 aagaagattt aattggtatt acatatctat catttctttt acttattata aactcttgta
    10741 tatacttttt atttacagtt gatgttataa atttatttaa tctatctttt atctttcctt
    10801 ctgtaatttc tatatttcgt cttatctttt ttaattcttt actagcatta gaatcaactt
    10861 tattagattt tatacagtaa tttatctcat cttctatact tttacattct gttatattta
    10921 aagcataaga acttaatgta ggtgaataaa attctttttc taacataaaa gctttcatct
    10981 tcctacaacc tcttaaaaaa tcttcaatat ttacaagttc aacaggttct attatcattc
    11041 ctttttcaat tttatctatt gtagaacctg cattaaacaa tccttcaagt ggtatgtgat
    11101 tactattttc aattatcttt ctagcttctt tattttctgc taatttcctt cttactactc
    11161 caatattccc actaggagtt aatttatcta ttaaattttt tcctagcgaa cttacacaat
    11221 gtatttttat taagtcttta acttcattta gttgtaatct ttcaaatgta ttactattca
    11281 ttattttttc tcctttattt ataagtcatc gtcttttaaa tcaccctatc atttactttg
    11341 ataatagtta ttttgcgaac aacttaataa ataaggagtt attatatatc aaactcctta
    11401 tttattaaga agtttaactc cggactcatt aatgttagta ttttttttca taaaacactt
    11461 ctccttttct attcttattt aaacacttat atcagtgcat ctaatattat tccataaatt
    11521 atatatttat gtcaataaaa ataatgttat taatgttttt gtacagtgaa aatttttata
    11581 gtgaaaataa gcttatactt tcatttatat ttgggaatca cttatattgt catcaattca
    11641 tgtatgtgca gtttccaata cagtctaact ttgtaatcat tatatatcaa agaatttagc
    11701 tctataaatt atcgtctcta caaaataaaa aaatagctaa taataaaaca cttttaaatg
    11761 ttccataaaa ttagctattt ataatataat tttaatcttt tttaacttta aaaattatcc
    11821 tttataagta atcaatggct tcatagttgc cactacttga ataagttcat attctatcaa
    11881 actttcaata atctgctcta tattcttata tgcctctgga gcttcttgaa ataataaatt
    11941 tacatcatta catataatct gacttttaaa tttagtttgt tttatagtat ctttactata
    12001 cttactttta aggcgcgatt tacaaactga acgagaccat tttctacctg ctccatgtga
    12061 tagagaatat aaagatatct ctgtattttc agtaggcata actatatatg atagactgcc
    12121 tcttgaacct ggtataatca cagctcctct ttcacttgaa acagcacctt ttctatgtat
    12181 aaatttatct tcccttttct ctataaagtt atgatttata gagaatattg tttcaacatc
    12241 tccagatgta cctattgact gcataatttt tttactgata gcttcacgat tacgctctgc
    12301 ccacattaaa gcattatcat gttttttaat ataatctatt gctttctcac tttcaacttc
    12361 aagtccatct ttatcataaa atttttttaa aatatcttct ccataatttc ttgacccaca
    12421 gtgaactaac atcataatat catcagatga aaattttaat tgttcaaatt gttctttatt
    12481 ataaatttca cttatacatt gaatttctac aaaatgattt ccactcccta tagttcctaa
    12541 atttaaaatt ggacattctt ctttatatgt gttttttatt tctatatcgg acaaatcttt
    12601 aatcttacta agtgacttaa tccatttgtc ttttttaaat ttctttttta gaaccccagt
    12661 tttaaataaa gtcattccgc atcctatatc atttccaatt atatgtggat aaataatatt
    12721 tttagtctca actgctaaac ctacaggtat tttacctgta tgtaagtcag gtaatcctac
    12781 tactcttaaa gttccattta actttgaaat atcttcaagt tgtttccttg ctatatcttc
    12841 aatccaacat ttattacttg ctattatttt tatattactc ataatttgct cctttttaat
    12901 attctcctgc ctttaaaaag tagcaaaaaa ctgtgacctt tagccacagc ttttttattc
    12961 taaactgtaa aagcaggtgg ctatttgtta aaatactcct agacgtttaa tacctcatta
    13021 ttttttgtta acataataac cacttccttt cataatttaa gactacacta aaatttctat
    13081 gtatatcatt tatagacatt gattttaaaa tacttaatat acaattttta tattatggaa
    13141 ctaataataa tcattgaaat catgactata gctagaccgg caacaacaag ttttttatgt
    13201 aatttttttc tcattttact tttatattct tttttaactt gtataacttt gtcttgtttc
    13261 tgttcttctt ctttctcatc ttcaacttct atatatgctt tttcatacat tactttactt
    13321 aaatcaataa taatatcatt ggctctggta tacttattat ttcttccaag aagccttttt
    13381 ataacattta taagttcagt atttccatta attgctttta tactattcca atctaatccc
    13441 ttatcaatag attgtagcat tttttcttct gaatttgatt ctccaaaagg caatttttta
    13501 aatatagatt caaatagaat aagacctgtt gcaaaaaaat cactttcttt atcagtataa
    13561 tttatacata gttgatgtgg gcataaatat ctcctgtttc catagcttct tgtattaacc
    13621 ccattatttg cttttgtaat tccaaaatca caaattttta tattgtattc tgtatctact
    13681 attatactac tcgattttaa actaccatga tatgaatgat tcctatgtat catttctaaa
    13741 gcttttaaaa cttgtatcat tatgtttaca attgcttcta aatgaagata attacctaga
    13801 attaattcat ctagtccgat accattaaag tcttcactta caacataata taatgttgtt
    13861 tcttctgtac agtgaatccc aacatctatt atttttagta tataaggaga gtttatctca
    13921 tctaaagcag tactttcatc aattaaattt gaaacaaaat cttcacaaat ataattattg
    13981 tgctttataa cttttattaa cacatttctc ctgtaaaaaa catctctagc tttatagatt
    14041 ttgttaattt ctaaaacgtc atcagaattt actacctcat atctattgcc tataaaattc
    14101 aaccatgtca cctcctcata cattttatat aactaaatct atttacaatt ataccaatat
    14161 ataggaatat tttctatata ttaatgattg taatattaaa acaagaacta atagtgttaa
    14221 tttttacaaa aaaggctgtc tcaaaataga gatacgcttc ttttgtattg ttgaaatgat
    14281 gaaaatatat ttgatttcac ataaaaagag tgtctcataa actaaaaagt tcattttgag
    14341 acactccctt ttatattaca aatatttctc taaaaaatta tctatttttt taattcttta
    14401 taagaactat ttgatatatg ttcttttttt atgacctttc cacttgaatc tttaaatatt
    14461 cgatatgtag aatatttatt ctgaccagtt tgttttacct ctatagatat atttggtttg
    14521 tcaccagaat taccatagat tactgatgat acacttcctc cacctgcata atttttaata
    14581 tatacaggat gcttatatgg atttttaaac tttaagttta atcctccatc gctcacagta
    14641 gcatctcttc ctttaggcac ataagtagat gcagatgaat gatttgtaac ttgagttatc
    14701 tccatacccg aaagaagagc cgcattataa actgttgaag atgtttgaca aacacctcct
    14761 cctgctgatt gttctagctt accataaact ataacaggtg catctttgta accatttgct
    14821 ttattactag gtcctgtaag tttattgtat gaaaattctt cacctggcat taataataca
    14881 tcactagttt ttcttgctga taatcctaca ttatatgacc taccctctac agcttgtgaa
    14941 taagtagttg aatattgacc tataacagaa tttacagttt ttacttgttc agttgttata
    15001 tctggttttt gaagatttac tttaagttct aaagttttat gctctttatt ttttatcata
    15061 ttatatatag actctttatt tgctgccaaa tcaaattctc tacctacaac agagtctgta
    15121 taacttagtc caccacttcc aacactaata gaagcatttt tcatcttaac atttatacta
    15181 tctgctatag aagacacttt ggaactaagt tttgcctcat catattcagc ttttatcttc
    15241 atatttgcct tattcactct tatatcaata tattttttta agttttgaaa ataggaccct
    15301 ttttttgtac tttcataagc atcttttaca acatcttctg tatcatattt taaatcaata
    15361 tcttttggtg atattgtata ttttttccca tcataagtaa gatttaagtc ttctggagta
    15421 tacttatctg ttatagcttt taatgcctct gctttagtca tatcagatac atttactcct
    15481 tctatatata catttttagc gattttccca ttgtacagaa atttactgtt aaaaaaataa
    15541 gtaaatccac ccattattag aactaaagct gccaatacaa ttaaaacact tcgttttttt
    15601 tctttaccta atcttgaaac tcttgttgct cttctgccca taacttcacc tcattttaac
    15661 actagcttaa atttgcataa tagagttccc atttcaaaac taccttagat tatatttgaa
    15721 tagcttttgt taaacaagga atttaatcaa atgtaacttt attgtaaatt tatgtcttat
    15781 aattagtttt atttttgata ttttttatta tatttctttt actatttctt aacaaaaaaa
    15841 ttgtttattt tataacaact aatttcattt atattgaaat ttaaatgtaa cctattacag
    15901 gataatggtc tgacaggtaa attttttcta ctgtgtatcc ttttagttca gtatttttat
    15961 taacaaaaat gtaatctatt ctagagtttg atttttcaaa tgttggtaag taagacttgt
    16021 ttagtgaaat agccatatca ttaaacatac ttaaaaagac atttttctca ttaaaatcac
    16081 cacataaaat aactatcccc actaatctgt tcctatagtc tattatttcg tctaattgtt
    16141 ttgctctctc ctgcctatca agtcccaagt gagtatttat tacatttata attcttccat
    16201 atgcatctat agttatacaa agagctcccc gttgttcttt tttgctagtt aagaaaaaat
    16261 gattactgtt taacatttta gatgttgtaa atgtacaaat accatatatc atatttactt
    16321 tttttacatt tgtagcaaag acaccatcca tatttaaaac agcttttaaa gctaaaaatt
    16381 gaggatataa tacttcttgc aaacaaatta catcacaatc caattgtttt aaatataacc
    16441 ccattttagt tagagttaat ctattatttg aatccatacc tttatgaata ttgtaggtta
    16501 ctattttcat aataatatca cctcttatgc aatataatac ttactaaaat ttaaacttat
    16561 ttacttttca cttaagacca ttatttatct tataaaattg agtacttata aactttatca
    16621 caaaaaaaac ctaacttaag tatttatatt ctacataagt taggttttat aaactattat
    16681 aatatttatt atttcattca tttctaatga tgattctcct tttttatctt tttcaatttg
    16741 ccttcactaa caacaaataa aaatcccatc ttcttgtata tttcatccaa ttcaattaaa
    16801 gttacttcac cattttttaa atttgttaat gttatatctt gtattcttct tgatggaatt
    16861 atcataagtt atcaacactc ctttaaattc ttcttaatct ttatatttaa atatatttat
    16921 gcattctgat atatattcat aaattattaa aataaattca aaaaacaccc gttctgcaaa
    16981 cattcgttct gtatatttat tatacatcat acagacgttc gattcaatat aaaaattaaa
    17041 tatatctcgt ttttagtaaa ttttacaata ttatacacta aatatgtcaa aacatcttct
    17101 tgaaatagat tatcttgtca aacaaaaaaa gccatttcag taaaagcttc tgcttaaatt
    17161 gaaatgactt ttcttattta aattattaat tttataccat atttttatta agctaacata
    17221 tgtaatattt gagttaccat aagagcacaa taagtcccta taatatttcc tagaagcccc
    17281 ataagtacac ctactggtat taatacagga ttgtgaaccc cagcaatcat tggagctgta
    17341 gttactcctc ctatattagc tatacttcct acttcacaag taaataaatc aagtttaaat
    17401 agtttagcaa gccctataaa tgaaatagca tgtacaagga ctactaccaa tccaaacatt
    17461 atgtaaacag gtgcttctga caatccaaag aaatttgctt tactacctgt agctgcaagg
    17521 agtaaataca taaacacatt tcctaccagt gtactccctt taagctttga tatttttgtc
    17581 atacccaata atattgatac tgtagatgca acaagtacta cccacatagt ttcattaagt
    17641 atacctgaag ttggaagtat cttggataca atttgtgcaa aagacgcaac tccaaaccca
    17701 acagaaagta aaatcataag ttctacaaac gtaggtgacg tattatcttt attttctttt
    17761 tcaagttttg atgtaacctc atctataaaa cttgtatcgc actttgtcca tttgttaaat
    17821 ttaggtccaa atttcacaga cattagacaa acagacatcc atactgtata tcctatagaa
    17881 cccataagta ttgcataact aagtccttct tctgcaactc ctagagcatt agctgctgca
    17941 atcatatttg atgagccacc tatccatgaa ccagatgctg ccccaagaat tttccatgaa
    18001 tctgcaccca ttgaattttt aaaaattatg aatgctataa caaatccaag cataaatgta
    18061 aatgtagcac agaaaaatga taataacatt ttaggcccca tctttaatat ttttcttaaa
    18121 tcacattgaa ttaacaaaaa cactaacatt aatggaagga agttcactgt tattatgttt
    18181 tgatacgttc caacatcttc attctgtgca aataaaccaa atgatccaag tatagctgaa
    18241 cctaagtata ttaaaagcat tggattaata acatcaaata ccttccattt caatttatca
    18301 accataaaaa aaattacacc tacgaataca accaagaaac tacaatatac aaatccagtc
    18361 tcaatcacat tatacacacc ctttcttttc ctaattaatt tgatttttat gatttctaag
    18421 taaagacttt ttcagataat agacaattaa aataaatact tttatctata tcatgctaat
    18481 taaatacata tatacctaac tattgacata tattaataaa gatttgcaca ttaattactt
    18541 tagaaatgaa taatctgaat ttaaaatctt tttcaacaat tattttatta ctaaaatttt
    18601 tatttgt
//
LOCUS       DACTZW010000084        17581 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.084, whole genome shotgun sequence.
ACCESSION   DACTZW010000084 DACTZW010000000
VERSION     DACTZW010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17581
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.084"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(214..597)
                     /locus_tag="JAM15_15130"
                     /pseudo
     CDS             complement(214..597)
                     /locus_tag="JAM15_15130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     regulatory      823..920
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            1377..1577
                     /locus_tag="JAM15_15135"
     CDS             1377..1577
                     /locus_tag="JAM15_15135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013859190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAT6799585.1"
                     /translation="MNNGIVKWFNNEKGFGFISMEGRDDVFAHFSAIQTSGFKSLEEG
                     QQVSFDIVKGARGPQAENITIL"
     repeat_region   1940..2170
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=2006..2035
                     /rpt_unit_seq="actttacataccacatagttgatataaaac"
     gene            2397..2579
                     /locus_tag="JAM15_15140"
     CDS             2397..2579
                     /locus_tag="JAM15_15140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HAT6799586.1"
                     /translation="MFKFYNNATLMFLSGTNIKTISERLGHADIKITMNSYSQFLEEM
                     DREAFENLSKILFIVF"
     gene            2650..3495
                     /locus_tag="JAM15_15145"
     CDS             2650..3495
                     /locus_tag="JAM15_15145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799587.1"
                     /translation="MNIIKSITLLLTLLIVILMTGCSPRESASEVAKKYIDKMNSGDY
                     ETAYSLLSKDSKKKISIENLEEFQNILVSTKRIISYKIGKEKIIKKYKHDGKEYKNVV
                     KLEETFNIKNLLYKKDDSLKVNRYFVVENNKYKLLLYESFKKEFGINSMDLAQLKLND
                     FGLKYFKEVDLILKKAIAINPTDSKLYYAQACNYMNFDGFPGYSDTTYNALDSINNSL
                     KYLDKNDSDYKKNASNIYNLKGVILMFHKRFDEAQQYLNKALYFNKDNEDPKYNLNTI
                     KKHLN"
     gene            complement(4425..4757)
                     /locus_tag="JAM15_15150"
     CDS             complement(4425..4757)
                     /locus_tag="JAM15_15150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HAT6799588.1"
                     /translation="MNTREMKEYRGFYNKKLSETDEFFRVFGSLDDKTYSEGAISKKN
                     KELMGLAISILSRCDECICYHIEGCINSGASKDEIIEAIKIGVIGGGSITYPNARFAI
                     KILEEFNI"
     gene            complement(5001..5642)
                     /locus_tag="JAM15_15155"
     CDS             complement(5001..5642)
                     /locus_tag="JAM15_15155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HAT6799589.1"
                     /translation="MKKAINKQFILSTLICFIPFIVSIYFYNRLPNEVAIHFDNYGNP
                     DNYAPKVIAAFGVPLLMLCIHLYTWFRLENEPKKANFSNVIQNLSKWGVAILSVILQI
                     LMVLYSTGVSLESNFYTGLILGIIVILFGNYLPKCKQNYSVGIILPWTLDDEDNWNKT
                     HHLAGWIWLIGGILLIINAFINIPFYNIFVIFVIVILPFIYSYLMYKISGKNN"
     gene            complement(5623..5916)
                     /locus_tag="JAM15_15160"
     CDS             complement(5623..5916)
                     /locus_tag="JAM15_15160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HAT6799590.1"
                     /translation="MGFPETFKALSDPIRREILVMLRENKMSAGEISEKFNMTNATIS
                     YHLSQLKKAGLIFETKYKNFIFYEINISVFEEVMLWFSQFMEKGEKDNEKSDK"
     gene            6310..6369
                     /locus_tag="JAM15_15165"
     CDS             6310..6369
                     /locus_tag="JAM15_15165"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799591.1"
                     /translation="MIEYIYYYNNKRIKKINLA"
     gene            complement(6885..7637)
                     /locus_tag="JAM15_15170"
     CDS             complement(6885..7637)
                     /locus_tag="JAM15_15170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HAT6799592.1"
                     /translation="MFSVIFLCIGGFLAAFVDSIAGGGGLISMPVLMAIGVPVHLAIG
                     TNKFAASAGCISSAYRYAKSGKINNDLLKKLVPFTIIGSVLGVRCVLSISEEILNVLV
                     VVMILIVAIYTFISKNLGQEDNFEAVNKKNLRLGMLMALIMGFYDGFFGPGTGTFLTF
                     GFIKIYGYDFLHASANTKILNLTSNITSLLLFMINGQVDYKIAIVFALVMIMGAYVGA
                     KVAIKKGSKMIKPIFLVMALFMVVKLVYQTLV"
     gene            complement(7696..9351)
                     /locus_tag="JAM15_15175"
     CDS             complement(7696..9351)
                     /locus_tag="JAM15_15175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAT6799593.1"
                     /translation="MVDFIESNNEVQKFDWGEVMWIHEPSKTQFNRLSAGIVRFFPGN
                     CQEKHFHLSEEQLLYVIQGEGIQMIDGKKVNIKETSIVYCPPYSEHEIINTGKIDLVI
                     LITYVPHKFSSLRQIPIVFSENNIQELVNVNIIENLANQISNILKLRISVYDLKYRGI
                     FETKKENKFCDICKNIKPCTKKLVKSINNDNFEKVYHCEYGVSSLEIPIVLEENIVGY
                     IECGNFIVYKSIDIDKNLSELSSSSGIDIKYINKIYNEFPLNPKSRLYVLKENLLMMS
                     EFIQEIAKRNFFENQLSIKDEEILKSRKENIRLEEALKKANSRLLEEEYIINPIDMFN
                     NSSKEYPFELELYIEKEIKNMNLEGVYNLIDTNKLRYNDVRDTIQEMIFVLSRTVLRD
                     LEDLKLISYLRNKYNKKISLVDSDEDLWNVLFEFSKECIDKNRAFWRKDKGNLIENIN
                     EYIKKYYKENINLNSISDVFFISPNYLSSIFNERNKVSITEYINLLRIEESKKYLLDR
                     SMSISDICKKVGFNNSSYFSQIFKKFNSITPNEYRKNMLDNKY"
     gene            complement(9580..9948)
                     /locus_tag="JAM15_15180"
     CDS             complement(9580..9948)
                     /locus_tag="JAM15_15180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAT6799594.1"
                     /translation="MKYSITDVSKITKISSSAIRFYEEKGLLLPINRKPSGVRYFSEE
                     DVERLIFIKELKNTGLSIKDIHECFHFCDMGDGTIDKRIQLFQQHKQNIKNKIHELES
                     CMNKIDEKIYYLKEKKMCKK"
     gene            10097..10891
                     /locus_tag="JAM15_15185"
     CDS             10097..10891
                     /locus_tag="JAM15_15185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase"
                     /protein_id="HAT6799595.1"
                     /translation="MEKYATMIKEKLNEGKVLCGVAVSLSDSVVSELIGISGYDFIWI
                     EGEHSALDRKDIQQHMIAAHAGGAASLVRLVNSDPDLVKPIMDMGTDIICFPFINTVE
                     DAQKAVAACTYPPNGIRGYNPQRASYYGNMNYFDYVKNTNNETLKMMLIEQKAGYDNL
                     EEIVKVEGIDIIALGPGDLSLDMGFSGYMNRIEIKDMISHAAEICKKYKMPFIIFPTI
                     EKKSIEEWVNIGANMLCFAQDTTFITYVINQLLSFYNEIVPIQKQH"
     gene            complement(11044..11472)
                     /locus_tag="JAM15_15190"
     CDS             complement(11044..11472)
                     /locus_tag="JAM15_15190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HAT6799596.1"
                     /translation="MSKIYIVYWSGTGNTEKMANFVAEGVKLKGKTPEVLDVSLLKPS
                     DLKEEDKFALGCPSMGAEQLEEGYMEPFVSELESMVSGKQIGLFGSYGWGNCEWMRDW
                     EERMQNAGATIIGGEGITAMEDPNEEAKDECIELGKTLAE"
     gene            complement(11948..12886)
                     /locus_tag="JAM15_15195"
     CDS             complement(11948..12886)
                     /locus_tag="JAM15_15195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HAT6799597.1"
                     /translation="MNKRMKLIPYEINENLRGAKNKFPYGIKQMNARGMWDEGYTGKN
                     IVVGIIDTGCDISHPLLKGKIIGGANFSDDSNGNKNIYEDFNGHGTHVAGIIAASNYN
                     NEVMGVAPDCKLLIAKALNKDGTGTYQSIINAINFAVNNKVDIISMSLGGNKDDKNLK
                     NAVMQAVKNNISVVCAAGNNGDGDSSTSEYSYPASYAEVIEVGAINENYLVEKFSNSN
                     TTIDLVAPGRNIISTYMDNKLAIMSGTSMSAPYVSGSLALIKEWAREEFERDLDEAEL
                     YAQLIKCTRALGIPRTEQGNGYLYLNLYKYKNNSKR"
     gene            complement(13399..14211)
                     /locus_tag="JAM15_15200"
     CDS             complement(13399..14211)
                     /locus_tag="JAM15_15200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAT6799598.1"
                     /translation="MFYNAKSCQMMIGSNTVNYIEFGSGKKTLIILPGLGDGLFPLHG
                     KIQAIAFAFKYKQFTKDYKVYVFSRKNQITEKYSTRDMAKDQADIMKKLGIMKAEVMG
                     VSQGGMIAQYLAIDYPELVEKLVLAVTSSKQNDTIQNVICSWIDMAKKQNYNGLMIDT
                     AKKSYSERYLKKYQLFIPFLGKVGKPKDFKRFIIQATSCIEHNAFSELNKITCPTLII
                     GGANDKIVGNNASFHLAEKIKKSEIFIYEGLGHATYEEAQDFNERVLEFLNK"
     gene            complement(14237..14866)
                     /locus_tag="JAM15_15205"
     CDS             complement(14237..14866)
                     /locus_tag="JAM15_15205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAT6799599.1"
                     /translation="MNREEKSKNSKEKIIQSAFSLFSSKGYDSTSTQDIINLSGLSRG
                     AMYHHFKTKEDILRSVTKELYSQMNNFLEHLVADDTLTANEKIIELVVHSANDYTRRK
                     MVHCSWLEKIPFALIEEVRNLNNVVAPNIAKIIKQGVENKEFSCEYPEELAEMLVFSI
                     DILLDPVLFKREYSEVCNRLDFLLFMLKKMDIPLIGECGIQKFKDLFKQ"
     gene            complement(15211..16866)
                     /gene="ilvD"
                     /locus_tag="JAM15_15210"
     CDS             complement(15211..16866)
                     /gene="ilvD"
                     /locus_tag="JAM15_15210"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007060838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HAT6799600.1"
                     /translation="MRSDIKKGIEGAPKRALMYGMGLTKEEIERPLIGIVNAQNEVIP
                     GHLHLDEIAEAAKNGVRMSGGLPLEFPAIGVCDGIAMGHVGMNYSLASRELIADSIEA
                     MTMAHGFDALVLIPNCDKIVPGMLMAAARLNIPSIVVSGGPMLPGKKNGKVYDFNSAM
                     EGVGACKDGTVSEEELEELAMNSCPGCGSCSGLFTANSMNCLTEALGMGIPYNGTAAS
                     HSGERKRIAKYAGMYVMELLKNDIKPRDILTIDAFKNAIAVDMAMAGSTNTVLHLPAI
                     AYESGIEFNLDFFDEISEKTPCLTKLSPSGKHHIEDLHMAGGIPAIMNELSKINGINL
                     DCKTVTGKTIGENIRNCEIENEEVIHTLKNPYSNQGGLAILKGNLALNGAVVKKSAVA
                     EEMLVHEGPARVFNSEEEAVNAIFGKKINKGDVIVIRYEGPKGGPGMKEMLSPTSAVA
                     GMGLDKHVALLTDGRFSGATRGASIGHISPEAMEGGLIGLVEEGDIISINIPDKKLEL
                     KVDEVEIENRKLKFKPLEPKIKHGYLSRYAKLVTSANTGAVLK"
     gene            complement(17190..17489)
                     /locus_tag="JAM15_15215"
     CDS             complement(17190..17489)
                     /locus_tag="JAM15_15215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799601.1"
                     /translation="MKWIKWYSITCICIFIVVAFYMFIFPNKIETIDTSSAYSFVEKK
                     VPNSAVYQGYKKNPVDGTTTIYYSYDNSTHIVRLSHPEDYSRKINWDKVSNIRFD"
BASE COUNT         6121 a         2768 c         1842 g         6850 t
ORIGIN      
        1 acagtaattt atctatagtg ttacttatat tttatatata tggctatttt tcaacatttt
       61 acaatatata taacatttat ttttttaact tttgtcagta aaatgtcagc aaaacacttt
      121 atccacaatt ttcatataag ttttccacaa attatcccca gtattatcca cataaaaaag
      181 gtagcactta tattattagc taccttttat ttattaatct tcatatttcc agctttttat
      241 ccaacttcct atttctatta ttttttcttc agttatttct tctccatcgt gtaattttga
      301 aattaattct gataaaggat tgttatgtaa acctctaaaa actctttttc cctctatttt
      361 gagatattct ctctctttta ttaatactgt atagtgtaca tgcctcccaa ttctctatga
      421 tattaaaaaa ccttttttgg ttaatctagc taaaagtata attgtagttg tatgcttcca
      481 accatatgtt ttttctattt catctgcaac atcttttgat attacagttt tataaccagt
      541 attccatatg catttcataa tttttaattc tgtatctggt aattttttat ttagcataat
      601 atattccttc tttcaattta tgtcacttct tcaaatttat ctagcttaaa ttataatagg
      661 agctttttag aacaaaaact atatttaatt tttaccaggt actctacgtg tttagtctgt
      721 ttttaagtgt aaaataatgt tcatatctat aaatttattt aactttcaaa caatcctgtt
      781 gaataataac taattctatt gtattatttt agttgtagaa taaaactaaa tcggcaaaac
      841 tagagaaatt tagtgacgca aagctatagg gactaagact tatataaata tcttatgagt
      901 tatgtcagcc agttgccaaa gagatagtgt tctttttgtt tttatgaaag ttttttaggg
      961 ggataataat ttatatgttt ggaaataaaa tggataaatg tacacatgta ttgactgctt
     1021 atattagcgg ttcgtatgat tattgtaatt ttttagatac acaattagat gattttatat
     1081 tagagtacgg agaaagtgta gtagagtctt gtttgcacca agtgatggta ttggtaagta
     1141 agtataatta gatagacatt gatttctaga gaaccctttt tagttttatc tacatttata
     1201 ttaatatata gcaatgtaaa acgcttaaat atatttttaa tattaagaat aactaaaatg
     1261 ttgactaaaa aatataatta agtagacatt tctattaatc tatgatacaa tagtatttgt
     1321 ggtaatacac aattaaatca agtatatctt gatataggtt aataggagta tttttaatga
     1381 ataatggaat agtgaaatgg tttaataatg aaaaaggatt cggttttata tcaatggaag
     1441 gtagagatga tgtgtttgct catttctcag ctatacaaac ttcaggattt aaatcattag
     1501 aagaaggtca acaagtaagc tttgatatag ttaaaggtgc tagaggtcct caagcagaaa
     1561 atataactat attataatat atagattttt cgggaaagac tctttttaga gtcttttttt
     1621 attgttagta tatgtaagat aatcattggt gaagtaaata aggtatattg agtaatgttc
     1681 ttgatagttt atatgctaat gaatttcaaa aaaataagca ctcctataaa aagagtgctc
     1741 ttaatgtaaa tataagcctt cattggtcca gcctaatacc ccgtattctc caagttctaa
     1801 ctctttttta tatacattat cactttcagc catatctaac acaatcattt cttctttaga
     1861 atcaatttgt aaaatatgag gactgtgtgt tgtgacaatt atttgtgttt ttaggagaat
     1921 tgcttttaat gtaataaaaa gtttacatac aacatagtta atataaaaca aaattatttt
     1981 tgagaatgag ctaaataaaa tcttaacttt acataccaca tagttgatat aaaacgaagt
     2041 tattatagct tcttcaatag gtctgtatct cgtctttaca taccacatag ttgatataaa
     2101 actttctaga ggtcttttac aagttggaca ctctgtttgt actttacata ccacatagtt
     2161 gatataaaac cccaaaataa acttagcatc tccaatgttt acacatatac aatgctctta
     2221 aaattgcagt gaacacgcaa tagtgcaatt gataatactt atcatatatt ctcaatacct
     2281 tatatttcaa ctgctaaacc tcaatttgtc acaaatatcg ctcactgcaa aatttctata
     2341 tttttattat atcatagcat ataattaata ttttcaatta atttttacat ttaattatgt
     2401 ttaaattcta taataatgca actttaatgt ttctttctgg aactaatata aaaactattt
     2461 cagaaagatt aggtcatgca gatataaaaa taactatgaa tagctactct cagtttttag
     2521 aagagatgga cagagaagca tttgaaaatt tgagcaaaat actatttatt gtattttaaa
     2581 gaagatgact tattcaatat ttgatgctag aatataatta ataaaaattt aattataggt
     2641 gattgtatta tgaacattat taaaagcata actttactct taacattatt aattgtgata
     2701 ttaatgacag gatgttcccc aagagaaagt gctagtgaag ttgcaaaaaa atatattgat
     2761 aagatgaact ctggtgacta tgaaacagca tatagtttat taagtaaaga tagtaaaaaa
     2821 aaaattagta tagaaaatct tgaagaattt caaaatattt tagttagtac aaaaagaata
     2881 attagttata aaataggtaa agaaaaaatc ataaaaaaat ataaacatga tggaaaagaa
     2941 tataaaaatg ttgttaaatt agaagaaact tttaatataa aaaaccttct ttataaaaaa
     3001 gatgattctc taaaagtaaa tagatatttt gtagttgaaa ataacaaata caagctatta
     3061 ttgtatgaaa gtttcaaaaa agaatttggt attaatagta tggaccttgc tcaacttaag
     3121 cttaatgatt ttggactaaa atactttaaa gaagttgacc ttatactaaa aaaagctatt
     3181 gctattaatc ctactgattc aaaactttat tatgcccaag catgtaatta tatgaatttt
     3241 gatggatttc ctggttattc agatacaaca tataatgctt tagattcaat taataattct
     3301 ttaaagtatt tagataaaaa tgattctgac tacaaaaaaa atgcaagtaa tatatataac
     3361 ttaaaaggag ttattcttat gtttcacaaa agatttgatg aagcacaaca atatttaaat
     3421 aaagccttat actttaacaa agataatgaa gacccaaaat ataatctaaa tacaataaaa
     3481 aaacatctaa actagatatt taatttttga atttataaaa tattttttta tgtataattc
     3541 agcactgaat cataatctct actaaactaa ttacaagttt aaattataaa gacttatttc
     3601 tatataaata ttactctata acaataagtt tcttatttaa attttaaaat attatctaaa
     3661 aatcataaaa aagaaggtat aaagagctac cctcaagctc aatatacctt ataaatatct
     3721 aaacttcatt ttttactaat ttttctatat ctttgataat atgttcttta gatttttttc
     3781 cagctatggc atcaaaaatt gcaacagcct ttttctctcc aaacttttct gctacatcat
     3841 taaagtctaa aaatctaaca ctttcttttg gtttaccaaa catataacac ctctcataca
     3901 tttttatata tttattataa cttctataga cttatttttc accaataaac gttagacaaa
     3961 ttagtccctt tattttttta aactagcttt accttcaaaa ttcttaacaa aaacagttta
     4021 ttctactcta taaataaaaa tagacaattt aatttgtagg aaactgataa tagaatacag
     4081 taaataaaac tttgtttaat ctatctgaaa aagttatcta ttaaaactgc tatgaattta
     4141 taaagaatat tctagttcat aaaaatacaa atatgtaaat ataatcacct taatattcaa
     4201 tttatttaaa ataaaaaatg tataaaagat ttaataatga caatatacta ttctcaatac
     4261 aatctatgat gtaaataatt taaaactact atattattta aaaatttata tttatatatg
     4321 caattctaaa aacttaataa gaagtgaact tagaaaataa agcttaattt caaagactta
     4381 aatagaatat tattattagt ctaaataaac tacgtgtatc aaaattatat attaaattct
     4441 tctaaaattt ttattgcaaa tcttgcgttt ggatatgtaa tagacccgcc accaattaca
     4501 cctattttta tagcttctat aatttcatct ttacttgctc cagaattaat acaaccctca
     4561 atatgataac aaatacactc atcacatcgg cttaaaattg aaatagctag tcccattaat
     4621 tccttatttt ttttacttat agccccttct gaataagtct tatcatcaag acttccaaat
     4681 actctaaaaa actcatctgt ttcacttaat tttttattgt aaaatcctct atattctttc
     4741 atttctctag tattcatctt ctacctccta tgtttttctt ataagagtat cacactgtac
     4801 ttatattttc aatattaaat acaaattttc attttatgtt cattagccta atttatatta
     4861 ttttttgaaa tctcaataag ttatcatata agtaagattt tttcagaact aaaatagaaa
     4921 tcttagtaat ttctttatta tctatctcag ttctgaaata tattattctt atccaaacat
     4981 tattatagtg attaattata ttagttattt ttacctgaaa ttttatacat caaataagaa
     5041 tatataaatg gtagtattac aattacaaag attacaaaga tattataaaa aggaatatta
     5101 ataaatgcat taataattaa taatattcca ccaataagcc aaatccatcc agctaaatgg
     5161 tgtgtcttat tccaattatc ttcatcatca agagtccatg gcaaaattat tcctactgag
     5221 taattttgtt tacatttagg aagatagttt ccaaataaaa taactattat tcctaaaatt
     5281 aatcctgtat aaaaattaga ctccaaacta actcctgttg aatataaaac catcagtatt
     5341 tgtagaatta ctgaaagtat agcaactccc cattttgata aattttgtat aacatttgaa
     5401 aaattagctt ttttaggctc attctcaagt ctaaaccatg tatacaaatg gatacatagc
     5461 attaacaatg gtacaccaaa agctgctata acctttggag cataattatc tggatttcca
     5521 taattatcaa aatgaattgc aacttcattt ggtaatctat tataaaaata tattgataca
     5581 ataaatggta taaaacatat taaagtagat aaaataaatt gtttatttat cgcttttttc
     5641 attatctttt tctcccttct ccataaattg tgaaaaccaa agcataacct cttcgaaaac
     5701 tgaaatattt atttcgtaga aaataaagtt cttatacttt gtttcaaata tgagtcctgc
     5761 cttttttagt tgagatagat gataagaaat tgtagcattc gtcatattaa atttttcact
     5821 aatttctcct gctgacattt tattctccct caacataacc aatatttctc ttcttatagg
     5881 gtctgaaaga gctttgaatg tttctggaaa ccccaacacc atcacctcgc tatttagaat
     5941 ttcatctaaa tagaatataa cataacatcc attttatttc aataactatt tagaaaaatt
     6001 tctaaatagt tatttctaaa tatttattga aaattttcat attaagattc tcaatttact
     6061 taagtcgctt ttatataatc ttattttatc taattttttt aatttaacaa aagtgtattg
     6121 caccacaatt gttaaagcaa aaacctaatg actgatatac ttatatatat tacatatact
     6181 tttaatttca aattaaaagt agctaaatcc aatttaaaaa gtagttaagt cctatttaaa
     6241 tagaaaagaa tgaaataaga aatatactgt ataaaaatgc ataaaaacct ctactaatta
     6301 gatacaacta taatagaata tatttattat tataataaca aaagaattaa aaaaattaat
     6361 ttagcataac cttgttaaat atagatttga atatgaattt aaagttatgt aaaattaaaa
     6421 atacaggaat gaaaattcca ttcctgtata aaatctaact tttgagtctc agtacaatct
     6481 tattttgaga caatcttttt tgttttatat tttcttatat ttaaaatata acgcatatct
     6541 tatgcaacat attcatattt ttctttatat tctttcatcg catcattcca agcgtcttgt
     6601 actgttacac ctcttttatt agcaattttt tgtgccagtt caattatctt catagctctt
     6661 cttgatatgt tcataaacat tcctcctaca aattaccata tatttcatat atataaatca
     6721 aggttatatt tttatgatat ataatccttc tattgtaaga ttacaattta tatgtgtatt
     6781 atatatgaac tatattagaa gataattaga atttttataa agctatacga ttagattaaa
     6841 tataaaagct ttacaattac ttataaattt aaaaagtcta taaactaaac taatgtttga
     6901 tataccaatt ttacgaccat aaataatgcc attactaaaa atattggttt tatcatcttt
     6961 gaacctttct ttatagcaac tttagcacct acataagctc ccattatcat cactaatgca
     7021 aacactatag caattttata atctacttga ccatttatca tgaataataa caatgaagtt
     7081 atattacttg ttaagtttaa tatttttgta tttgcagaag catgtaaaaa atcatatcca
     7141 tatattttta taaatccaaa agttaaaaaa gttcctgtac ctggaccaaa aaaaccatca
     7201 taaaaaccca ttataagagc cataagcatc cctagtctta aatttttctt attaacagct
     7261 tcaaaattat cttcttgacc taaattttta gaaataaagg tgtaaatagc cactattaaa
     7321 atcataacca caaccaaaac atttaatatc tcttcactta ttgataatac acatctcaca
     7381 cctagaacac taccaataat agtaaatggt actaattttt ttaaaagatc gttattaatt
     7441 tttccagact ttgcatatct ataggcacta cttatacatc ctgctgatgc tgcaaattta
     7501 tttgtaccaa tggcaagatg tactggcact ccaattgcca taagaacagg catgcttata
     7561 agtcctcctc ctcctgctat agaatctaca aaagcagcta aaaatccccc tatacataaa
     7621 aaaataactg aaaacataaa attcctccat cattctcttt caatttttct tacaatatat
     7681 attatataat cttatttaat acttattatc cagcatattc tttctatatt catttggagt
     7741 tatactatta aacttcttaa atatttgtga aaaataacta ctgttattaa aacctacttt
     7801 cttacaaata tcactaatac tcatgcttct atctaacaga tattttttag attcttctat
     7861 cctaagaaga tttatatact cagttattga aactttattt ctttcattaa aaatagaact
     7921 caaataattt ggacttataa aaaaaacatc tgatatacta ttcaaattta tattttcttt
     7981 ataatatttt tttatatatt cgtttatatt ttcaattaga tttcctttat cttttctcca
     8041 aaatgctcta ttcttatcaa tacactcttt ggaaaattca aataatacat tccataaatc
     8101 ttcatcactg tctacaagtg atattttttt attatattta tttcttaaat aagatataag
     8161 ttttaaatcc tctaaatctc taagcactgt tctagacaat acaaatatca tttcctgaat
     8221 agtatctcta acatcattat atcttaattt gtttgtatct attagattat aaacaccttc
     8281 taaattcata tttttaattt ctttttcaat ataaagttct aattcaaagg gatattcttt
     8341 tgaagaatta ttgaacatat ctatcggatt aataatatac tcttcttcta ataatctact
     8401 atttgctttt ttaagtgcct cttcaagtct tatattttct tttctactct ttaatatctc
     8461 ctcatctttt atactaagtt gattttcaaa aaaattcctc ttagctattt cctgaataaa
     8521 ttcagacatc attaataaat tttcttttaa tacatataat ctacttttag gatttaatgg
     8581 aaattcattg taaattttgt ttatgtattt tatatcaata ccagaactac ttgataattc
     8641 agataaattt ttatctatat caatagactt atatactata aaattaccac attctatata
     8701 tccaactata ttttcttcta atactatagg tatctctaaa ctggaaacac catactcaca
     8761 atggtacact ttttcaaagt tatcattatt tatgctttta acaagttttt tagtacacgg
     8821 ttttatattt ttacaaatat cgcaaaattt attttctttc ttagtctcaa atattcctct
     8881 atactttaag tcatatacag atattctaag cttcaatata ttagatattt gatttgcaag
     8941 attttcaatt atgtttacat taactaactc ttgtatattg ttttcagaaa atactatagg
     9001 tatttgtctc aaactcgaaa atttatgagg aacataagta attaatatta ctaaatcaat
     9061 tttaccagtg tttataattt catgttctga atatggtggg caataaacta tagatgtttc
     9121 ctttatattg acctttttac catcaatcat ttgtattcct tctccctgaa tcacatataa
     9181 aagctgttct tcacttaaat gaaaatgctt ttcttggcag tttcccggaa aaaatcttac
     9241 aattccagca ctaagtctat tgaattgtgt ttttgatggt tcgtgtatcc acataacctc
     9301 tccccaatca aatttttgta cttcattatt tgactcaata aaatccacca taaactcacc
     9361 tcgtagtttt tatctaaata tttttttatt cctttaaata tcttcttata atatacatta
     9421 tcataatttt cttttttatt gtatagataa atagttatat agaacattgt ccaattcttc
     9481 ctaaaaatat gttgtaaaaa atctttcctc aaatgtttcc aattgaattt actctttata
     9541 ttagaaaaat caaaaaatta tttctttatt ctataaggat tattttttac acatcttttt
     9601 ttcttttaag taatatattt tctcatctat tttattcata caactttcta gttcatgtat
     9661 tttattttta atgttttgct tatgttgttg aaataattgg attcttttat ctattgtacc
     9721 atctcccata tcacaaaaat gaaagcattc atggatatct ttaatagata aaccagtatt
     9781 ttttaattct ttgataaata ttagacgctc tacatcttct tcagagaaat agcgaacacc
     9841 acttggtttt ctattgatag gaagtaataa acctttttct tcataaaatc gaatagcaga
     9901 tgaagaaatt tttgttattt ttgatacatc agttatagaa tatttcataa tctctacctc
     9961 cctaaatttt atatgaataa gaatattata aaaatacctt atacagtagt caacaaaaaa
    10021 gtattgactt caagttaggt tgaagttgta ctctttgaag tgtaaaagaa aacttacaaa
    10081 agagaggatg atataaatgg aaaaatatgc aactatgatt aaagaaaagc taaatgaagg
    10141 aaaggtctta tgtggagtag ctgtttcact gtctgattca gttgtaagtg agttaatcgg
    10201 tatatctgga tatgatttta tttggattga aggagaacat agtgctttag accgtaaaga
    10261 cattcagcaa catatgatag ctgcccatgc tggtggtgct gcttctttgg tacgattagt
    10321 aaacagtgac cctgaccttg ttaagcccat aatggatatg ggaacagata ttatttgttt
    10381 cccatttatt aatacagtag aagatgcaca aaaagccgta gcagcttgta cttatcctcc
    10441 aaacggtata agaggatata atcctcaaag agcctcttat tatgggaata tgaattattt
    10501 tgactatgtc aaaaacacaa acaatgaaac attaaaaatg atgttaattg aacagaaagc
    10561 aggttatgat aatcttgaag aaatagtaaa agtcgagggt attgatatta tagcattagg
    10621 ccctggtgac ttatctttag acatgggttt ttccggatat atgaatagaa ttgaaataaa
    10681 agatatgatt tctcatgctg ctgaaatatg caaaaaatat aagatgccct ttattatttt
    10741 tcctacaata gaaaagaaaa gtattgaaga atgggttaat attggagcaa atatgctttg
    10801 ttttgcacaa gatactacct ttatcactta tgttatcaat caattattat ctttttataa
    10861 tgagattgta ccaattcaaa aacaacatta aattataaat ctaattttat attaaaagag
    10921 actaatattt tatctatctc tattaaggat attttcttat gtatcataat attagtctct
    10981 cttattatta tatactgcta tcatcattag ttgctattta tactattttt ataatataca
    11041 aatttattca gctaacgttt tgcctaattc tatacactca tcttttgctt cttcatttgg
    11101 gtcttccatt gctgtaattc cttctccacc aataattgta gcaccagcat tttgcatacg
    11161 ttcttcccag tctctcatcc attcacaatt tccccatcca tatgaaccaa ataatccaat
    11221 ctgtttacct gataccatag attctaattc tgaaacaaat ggctccatat acccctcttc
    11281 tagttgctct gctcccatag atgggcaacc taatgcaaat ttatcttctt cttttaaatc
    11341 acttggtttc agtaagctca catctaaaac ttctggtgtc ttacctttta acttcacacc
    11401 ttcagccaca aaatttgcca ttttttcagt atttcctgtt ccactccaat aaacaatata
    11461 tattttactc atttttacct cctgtagtat tttttaatta atcaatagtt agttatagct
    11521 aactaacatc taaaaaacaa aagatttctt tatctgaaat ctctttattt ttctaaatat
    11581 agaatatcat agttgatttt gaaattcaat acttattgat aatatttatc atttatattt
    11641 tatattcatt ttataatatc aaaacactgt atcgtatttc taatctttca tagaaaaatt
    11701 tctaacttat agtacttttg catctcttat aaatctttta tatgtataag tacatagaaa
    11761 aacacacctt ttccagatgt gctatctata atatcgtata tttatttttc aattctaact
    11821 agctaatatg tttataaatt ttatcactta atacctttat acattgatgt aaaatcttac
    11881 acctaagtaa tttttattat ttgtctcgac tctatataat atagctattt tatcatcaaa
    11941 tcaaaaatta tcttttgcta ttattcttgt atttataaag atttaaatat aagtatccat
    12001 ttccttgttc cgttctaggt attccaagcg ctctcgtaca ttttattaat tgtgcataca
    12061 gttcagcttc atctaaatct ctttcaaact cctctcttgc ccattcttta attagtgcta
    12121 atgaacctga tacgtatggt gcactcatac tggtaccact cataatagca agtttattat
    12181 ccatataagt cgatataata tttcttcctg gagccaccaa atctattgta gtatttgaat
    12241 tactaaactt ttcaaccaaa tagttttcat ttattgcacc tacttctatt acctcagcat
    12301 aactggctgg ataactatac tcacttgtac tagaatcacc atctccatta ttacctgctg
    12361 cacacactac agaaatatta ttttttactg cttgcatgac agcatttttt aaattcttat
    12421 catctttgtt tcccccaaga gacatagata taatatcaac cttgttattt acagcaaagt
    12481 taatagcatt aattatactt tgatatgttc cggtaccatc tttatttaat gcttttgcta
    12541 ttaataattt acaatctgga gctactccca taacttcatt attatagtta gatgcagcta
    12601 taatacccgc cacatgagtt ccatggccat taaaatcctc atatatattt ttatttccat
    12661 tactgtcatc actaaaattt gcaccaccaa ttatttttcc ttttaaaaga ggatgagata
    12721 tatcacaacc tgtatctatt ataccaacta caatattttt accagtataa ccttcatccc
    12781 acattcccct agcattcatt tgttttattc catatgggaa tttatttttt gcacctctta
    12841 gattttcatt tatttcatac ggaattagtt tcattctttt attcatcata tatcctccta
    12901 aaaattttat tgcttataaa aatcatgaat tttattttat aataggttta taaatcaaat
    12961 taaaacctat atctacttat ttatatttat gatatatttt ttatttttag gagtcatatt
    13021 tttttgtata taaaataata tttagataac tatattaaaa aatacatgtt tgcttatata
    13081 caaaacttac taaaatatct ttaatatttt tgtatacaaa cagtatattt ttatataaaa
    13141 agctcataaa aattttgatt atatttttat aagttaacaa atgttgatat aatctgaatt
    13201 tacaaaattc ctctgtttgt ataagtgctt taccaataca ccaacatata atcacattga
    13261 agctatattt gtatttatag tagataatgt atcaaaaatt ggttaggtat agtaaaaata
    13321 ccagttaagc atattttcat gtttctattt ttaatattaa atttccaatg ttcatatgta
    13381 tatttttaac aaaggtgttt acttatttaa aaactctaaa actctttcat taaaatcctg
    13441 tgcttcttca tatgtagcgt gtcccaatcc ctcatatata aatatttcgc tttttttaat
    13501 tttttctgct aaatgaaaag aagcattatt tccaacaatt ttatcattag cacctcctat
    13561 aattaaggtt ggacatgtta ttttatttaa ttcggaaaag gcattatgtt ctatgcaaga
    13621 ggtcgcttga ataataaatc gtttaaaatc ctttggttta cctacttttc ctaaaaaagg
    13681 aataaataat tggtattttt ttaaatatct ttcagaatag gatttctttg ctgtgtcaat
    13741 cattaaacca ttgtaattct gcttcttcgc catatcaatc caactacaaa taacattttg
    13801 gatagtatca ttttgcttag aagaagtaac tgccaacaca agtttctcaa ctaactcagg
    13861 ataatcaatt gccagatatt gagctatcat tccaccttga gaaacaccca ttacttccgc
    13921 tttcataatt ccaagttttt tcattatatc tgcttggtct ttagccatat cccttgtgga
    13981 atatttttct gtaatttgat tttttctact gaacacataa accttataat cttttgtaaa
    14041 ttgcttatat ttaaaagcaa aagcaattgc ctgtattttt ccatgtaaag gaaataaacc
    14101 atctcctaat cctggtaaaa taattagtgt cttcttacca ctaccaaatt caatatagtt
    14161 caccgtatta ctgcctatca tcatttgaca actttttgca ttataaaaca tagtctattc
    14221 ctcacttttc ctattatcat tgtttaaata aatctttaaa tttttgaata ccacactcac
    14281 caattagagg aatatccatt tttttcaaca tgaacaataa aaaatccaac ctattacata
    14341 cttcactgta ttcacgttta aataatacag ggtcaagtaa aatatcaata ctaaaaacga
    14401 gcatttcagc taattcctct ggatattcac aagaaaattc tttattttca acaccttgtt
    14461 taattatctt agcaatattg ggtgcaacta cattgttgag attacgaact tcctctatta
    14521 aagcgaatgg gattttttct aaccagctac aatgtaccat ttttctacgt gtataatcat
    14581 tcgcactatg aacaactaat tctattattt tttcatttgc tgtaagggtg tcatcagcaa
    14641 caagatgctc taaaaaatta ttcatttgtg agtaaagttc ctttgtgaca cttctaagta
    14701 tatcttcttt agttttaaag tgatgataca ttgcacctct agataaacca gataaattga
    14761 taatatcttg tgtagatgtt gaatcatatc ctttagacga aaatagtgaa aatgctgatt
    14821 ggataatttt ttctttacta tttttacttt tttcttctct attcatattc ccctcctaaa
    14881 aaacagattg tctgtttgtt ttttattata tattttaata tttattatgt caagaattaa
    14941 ctgactttca atttcttcat agttcagatg gaacgaaaag cattccacat caaactttta
    15001 aaaagttgta ttacctcaac aaggtctaaa agatacatct ctatgctgta ctcgtattcc
    15061 ttataataga gatgtattgt tttcaaagat aatcaagatt ttgctgtgtt tttcatacaa
    15121 aataaaaagg atacctcatt agtgctataa cacctaagat atccaattaa tattttctta
    15181 actttttcta atttacataa atatagtcta ctattttaaa actgctcctg tatttgctga
    15241 tgttaccagt ttagcatatc tacttaagta tccatgcttt attttcggtt ctaaaggttt
    15301 aaattttaat tttctatttt ctatttcaac ttcatctact tttaactcta attttttgtc
    15361 tggtatgttt atagaaatta tatctccttc ttcaactagt ccgattaaac caccttccat
    15421 agcttctgga gaaatatggc ctatagatgc tcctctagtt gctcctgaaa aacgaccatc
    15481 agtaagaagt gctacatgct tatcaagtcc cattcctgca actgctgatg taggagatag
    15541 catttctttc attcctggac caccctttgg accttcatat cttataacta taacatcacc
    15601 tttgtttatt tttttaccaa aaatagcatt tacagcttct tcttctgaat taaaaactct
    15661 tgctggtcct tcatgaacta acatttcttc tgcaactgct gactttttta caacagctcc
    15721 atttagagca agatttcctt tcaatattgc aagcccacct tggttactat atggattctt
    15781 taatgtatgt attacttctt cattttctat ttcacaattt cttatatttt cccctatagt
    15841 cttgcctgtt acggttttgc aatctaaatt tattccattt atctttgaaa gttcgttcat
    15901 tatagctggt attcctcctg ccatatgtaa atcttcaata tgatgttttc cacttggact
    15961 taattttgtt aaacaaggag ttttttcact tatttcatca aaaaaatcta agttaaactc
    16021 tattcctgat tcataagcta ttgcaggtaa gtgaagtact gtatttgtag aaccagccat
    16081 tgccatatca acagctatag catttttaaa agcatctatt gttaaaatat ctctaggttt
    16141 tatgtcgttc ttaagtaact ccataacata catacctgca tattttgcta ttctttttct
    16201 ttctccagaa tgtgacgcag cagtaccatt atatggtata cccatgccta aagcttctgt
    16261 taaacaattc atgctatttg ctgtgaaaag tccagagcat gaaccacatc caggacaaga
    16321 gttcatggct aactcttcta attcttcttc acttactgtt ccatctttac atgctccaac
    16381 accctccatt gcagagttaa aatcatatac ttttccattt tttttacctg gaagcatagg
    16441 ccctccactc acaacaatac ttggtatatt aagtcttgca gcagccatta acatacctgg
    16501 cactatcttg tcacaattag gtataagtac caaagcatca aaaccatgtg ccatagtcat
    16561 agcttctatt gaatctgcta ttaattctct tgaagccagg gaataattca ttccgacatg
    16621 ccccatagct ataccatcac atacccctat agcaggaaat tctaatggca aaccaccact
    16681 cattcttact ccattttttg cagcttctgc tatttcatca agatgcagat gaccaggaat
    16741 cacctcattt tgtgcattta ctatacctat taatggtctt tcaatttctt ctttagtaag
    16801 acccattcca tacattaacg ctctctttgg agctccttct attccttttt ttatatcact
    16861 tctcataata ttacctcttt cttacttttt taaattttca taatattatt ataatatatt
    16921 tttctattaa ttaattacga aaattgtaaa aaaatattag catatactaa tgaaaattta
    16981 ttacgatttt ttatcaatat cttacacaat cgtattatat aatattatct tttcaatata
    17041 ttttataaac taatatattt tacaaattct tgagtaatat tttatgatat aaatcagaag
    17101 aagcacttct ataatagaaa gtgctcaact atgaataaga ttaataatat atttgcctta
    17161 gatatataga cttttataaa tattaaagat taatcaaatc tgatgtttga aactttatcc
    17221 caattaatct tccttgaata gtcttctgga tgtgataatc taactatatg agttgaatta
    17281 tcatagctgt aataaattgt agtagtacca tcaactggat tctttttgta tccttgatat
    17341 acagcactat ttggtacttt cttttcaaca aagctatatg cagatgaagt atcaatagtt
    17401 tctattttat taggaaatat aaacatataa aaagctacta ctataaaaat acatatgcat
    17461 gtaatactat accatttaat ccatttcata aaattcctcc tactttacca aaatatacta
    17521 ttattatttc catatattta taatatttat acatacgata aaatttttat atacctaact
    17581 a
//
LOCUS       DACTZW010000085        17448 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.085, whole genome shotgun sequence.
ACCESSION   DACTZW010000085 DACTZW010000000
VERSION     DACTZW010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17448)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17448)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17448
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.085"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(204..728)
                     /locus_tag="JAM15_15220"
     CDS             complement(204..728)
                     /locus_tag="JAM15_15220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAT6799602.1"
                     /translation="MENKNPIVTIEMENGKEIKIELYPNIAPNTVKNFVSLVNEGYYN
                     GIIFHRVIPGFMIQGGCPNGTGMGGPGHSIKGEFSGNGFTNNLKHERGVISMARTMAP
                     NSAGSQFFIMHKNSPHLDGQYAGFGRVIEGMDTVDEIASVRTDSADKPQTPQIMKSVT
                     VETFGIDYSDVEKN"
     gene            complement(793..1545)
                     /locus_tag="JAM15_15225"
     CDS             complement(793..1545)
                     /locus_tag="JAM15_15225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase"
                     /protein_id="HAT6799603.1"
                     /translation="MKLGLCLEGGGAKGAYQAGVVKALYDGGINKFYSISGTSIGAIN
                     GYYLYTGNVDNLEKMWTNIKDIQNGNVKIVNNTVDNSPAIDNLRELDDSNIEEMNFYV
                     NYVEVDNKVVSEKIVDVSKMPRNEAIISISYSGLLPSNPNATLGFKEQFVKDVQEGIY
                     DGFKLDGGLIRSALIEPLIGDNVDKIILISTKYNYELPEDIKKVYDEDKIIVVRPNTQ
                     FAPKDTLNFDDEFCKTIYQEGYEIGKNILDRL"
     gene            complement(1576..2874)
                     /locus_tag="JAM15_15230"
     CDS             complement(1576..2874)
                     /locus_tag="JAM15_15230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M18 family aminopeptidase"
                     /protein_id="HAT6799604.1"
                     /translation="MDSINFAKNLIDFIYDSPSSFHAVESTKEILDKNGFEELVLNQR
                     WNLRVGGKYYVTKNLSAIVAFVVNSEDIERDGFRIIGSHSDSPTFSIKPNAEIEAEKS
                     YLKLNTECYGGAILSTWLDRPLGIAGRVVLKGDSILKPNERLIDFKKPICIIPNLAIH
                     LNRSINDGHSYNKQKDMLPLVGMLNDTLEKDNFLIKQIASNLDVNMEDIIDFDLFLYE
                     FEKGSLIGANDEFISIGRQDNLAMVHASLNALVNTKGQHGVNVMAVFDNEEVGSSTKQ
                     GADSNMLLNILERICISMGKDREGFFESIYSSFMISSDLAHAIHPNIPEKHDPTNKPI
                     MGKGPVIKINASQAYTSDGYSIAIYKNICREANVEYQEFVNRSDERGGSTIGPISSTH
                     IDIPSVDVGSPILAMHSIRELGNVEDHYSIYKTFSKFFEI"
     gene            complement(2891..5155)
                     /locus_tag="JAM15_15235"
     CDS             complement(2891..5155)
                     /locus_tag="JAM15_15235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002845909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3553 domain-containing protein"
                     /protein_id="HAT6799605.1"
                     /translation="MNLDTLNPAQREAVEKTEGPVLILAGAGSGKTKVLTTRIAYLIE
                     DKGVQAPNILAITFTNKAANEMRERVEQNIGPETKDMWISTFHSCCVRILRKDINKIG
                     YNRSFVIYDSADQVTLVKDCLKELNLSDKVFEPKAVISAISGAKDKLYTPKQFKDINM
                     ADNRMVKIADIYALYQDRLKRNSALDFDDLILKTVELFKANDEVLAYYRSRFRYIMVD
                     EYQDTSKAQYELIKLLAREHQNICVVGDDDQSIYGWRGADIRNILEFEKDYDNVHVVK
                     LEQNYRSTQVILDAANKVISNNIERKRKKLWSEKKEGELIKIQLTGSEIEEADFIADS
                     IAQIARKENRPYKDFAVLYRANAQARPVEDALNRSQIPYNIYGGTKFYERKEIKDLLA
                     YLRVIQNPQDDISIKRIINVPRRGIGLRTIEKIEDRANLKQESIYSVLIDIETNSDIS
                     TKARASISGFVDIIGTLRTIKEVYPVSKLIEKVLDTTGYMDELVEIRNKNEKDLTGKG
                     EEAQDRIDNLREFISIALEFESSNDDTYENKDLETFLTSIALTSESNDEEDNDRVSLM
                     TIHTSKGLEFPVVFLTGMEEGLFPISRAIKSMSDSQIEEERRLCYVGITRAKEELYMS
                     LTEKRTLYGKTNVAIASRFMEELPEECIERLYKVKKELSYSKASYNMLDKYTKKYMST
                     ISKSKVADKVNATIKDSNKETNPDDIKLGSKVHHPKFGVGTVVSIIGTDVTIAFDQQG
                     IKKINKEYTTLNIL"
     gene            complement(5410..6228)
                     /locus_tag="JAM15_15240"
     CDS             complement(5410..6228)
                     /locus_tag="JAM15_15240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAT6799606.1"
                     /translation="MFKINNLTYQYEKNTNALLNINMDFSKGNVIGIIGSNGSGKSTL
                     FMNLMGILKPTSGEILFKEEKLKYDKRSLYNLRKNVGIVFQDPEKQIFYSKVYDDIAF
                     AMRNIGMDEKTIKERINKALVAVNGIDFIDRPVHFLSYGQKKRVAIASVIAMENEIVL
                     LDEPTAGLDPVSTRSIVDIIKGLNKNNIKIVISSHDMNLMYEICDYIYVLDKGILIDE
                     GKAENVFINENNIIQAGLESPWLVKVHRNMNLPLFKKEEDLYKYWKERELNTNK"
     gene            complement(6221..6919)
                     /gene="cbiQ"
                     /locus_tag="JAM15_15245"
     CDS             complement(6221..6919)
                     /gene="cbiQ"
                     /locus_tag="JAM15_15245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter T component CbiQ"
                     /protein_id="HAT6799607.1"
                     /translation="MLIIDKYAYTNRLSKVNPNKKVAIGVIFLIASMVIQNIFILSGI
                     MILMSILVVCVAGIDLKNYLKLLRIPMYFLFLSIGITLVNISFNKADLLYSFEFFSFN
                     VGISKASIDMSIHVLFRAMSCLTCVYFCILTTPFNQLIFFFKKLHLPDTFVELSMLIY
                     RFIFIFLEEFSEIYKSQELRFGYINLKTSYKSLGILGSMLYKRLMTRYDDMCISLDIK
                     LYDGKFHIVGDNDV"
     gene            complement(6922..7206)
                     /locus_tag="JAM15_15250"
     CDS             complement(6922..7206)
                     /locus_tag="JAM15_15250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     substrate-binding protein"
                     /protein_id="HAT6799608.1"
                     /translation="MSAKTKTKTNILLLLLVVALIIFPLLVNSGAEYGGADGQAESEI
                     TKINPNYKPWFNSPYEPPSGEIESLLFSAQAALGAGVIGYILGLQKGKRS"
     gene            complement(7196..7948)
                     /locus_tag="JAM15_15255"
     CDS             complement(7196..7948)
                     /locus_tag="JAM15_15255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HAT6799609.1"
                     /translation="MKQNIKLGVIAALMLIILTPATSNAMHIMEGYLPVKWSIAWGVI
                     FIPFFLFGLKSIGKIVKQDPKKKVLLALCGAFVFVLSALKIPSVTGSCSHPTGVGLGA
                     IMFGPSVMFVLGTIVLIFQALLLAHGGITTLGANAFSMAIIGPIVSFLIFKALKKKDG
                     NNAIPVFLAAAIGDLATYTITSIQLALAFPDPSGGVMASAIKFLGIFFMTQIPIAIAE
                     GILTVIVYNLITENGEKSILENNDKGVKANEC"
     regulatory      complement(8130..8322)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            complement(8454..10226)
                     /locus_tag="JAM15_15260"
     CDS             complement(8454..10226)
                     /locus_tag="JAM15_15260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase activation-like protein"
                     /protein_id="HAT6799610.1"
                     /translation="MKWIYDDYEFENRANNLSWTIAGDYNESIDISEKDYSSKEIGLY
                     FAIIAGARRKYVDWDIVKKYLTNRIRKGYNKDIILGLIQVILNTIVEEKVIKDRPGIE
                     DIRRNAYKDIVSRFTKIHNDNIMDKIKYTFVLYNMDKHPALDSMTRRIVNDIRNIDTN
                     QDMMEILKALDVIYLTYFEYILNGEENSLIDENNVESVEVNFDTFADFMYEELYSDEE
                     ENIIESDIDSISSSMLVEGVGDFDDSKCSNSADRVIYVDEDTANKIYSKIEHYYGKTY
                     LSKGEIKKIETQNCRNVHEGCRIHFTDGVLRSECNNVFQLKYVTRQKENNLGKFREHA
                     RMYRQQIKRLKESLSRILIEENAKSRVYSDCGTILANRAWRVGRSNNNKIFYKDIENE
                     KGKYVIDILLDASGSQSRNQGNVAIQAYIIANALTEVGIPNRVMGFSSFLDYTILKRF
                     KDYDDSIKNSENIFEYFCAGNNRDGLAIKSICSGLINRDEENKILIVLSDGRPNDVKI
                     GKSSERTLRGEKAYRGIVGLRDTANEVRKARKQNILVLGVFTGKESELEAERLIYGND
                     FIYSRDITRFSDVVSMYLKKIIRN"
     gene            complement(10240..11169)
                     /locus_tag="JAM15_15265"
     CDS             complement(10240..11169)
                     /locus_tag="JAM15_15265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAT6799611.1"
                     /translation="MDIIDNLRVQGVDEKLIEDVLYFRNYYGLEKDLEYRVTKSKTYF
                     YGKDILSMCIAAILEEENILLSGPKATGKNLLADNLGEIFNRPQWNTSFHINTDSSTL
                     IGTDTFIDNEVKLRRGSVYECAINGGFGVFDEINMAKNDAIVVVHSALDYRRIIDVPG
                     YERVNLHPATRFIGTMNYEYAGTKELNEALVSRFMVIDIPPIEEDKLMMILKNEFSDA
                     DEEKLIHFAGIFLDLQLKSQNGEISSKAIDLRGLMASLKTIRRGLKPTLAINMGLTGK
                     TFDVYEKEMVGDVIKTRIPNKWESIDVFPISHI"
     gene            11398..11586
                     /locus_tag="JAM15_15270"
     CDS             11398..11586
                     /locus_tag="JAM15_15270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAT6799612.1"
                     /translation="MEYMSCPEVAKKWGISERRVQKLCEESRIPGVSKLGYMWLIPKN
                     AEKPVDGRAKRRKEVQYE"
     gene            11579..12280
                     /locus_tag="JAM15_15275"
     CDS             11579..12280
                     /locus_tag="JAM15_15275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004069670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6799613.1"
                     /translation="MNSVLIIDDDKELCALMKKCVEQENLSAITAHCGAEGLHLLDKN
                     RHTLSLVILDIMMPDIDGFQVLKKIRETSNIPVIMLTAKNDEDDKVSGLRLGADDYLT
                     KPFSINELMARVNSLIRRYTMLNPAFITDTDCIIINGMIIDKTNRIVSINNIPVQLTS
                     KEFDLLAFLASNKGRVFTKKQIYTQVWEEEYAFDDSNIMSFISKLRKKIEPDPNHPFY
                     ILTVRGVGYRFNKEA"
     gene            12282..13205
                     /locus_tag="JAM15_15280"
     CDS             12282..13205
                     /locus_tag="JAM15_15280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015524239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAT6799614.1"
                     /translation="MNTSVYLLLILALSLIIIAYLVSVLLRVRIQLTLIKDALEDIKN
                     GNLNRRILTDENDITKQICYDINEIAINSQFQLIQQKQSEQAYKQLMTSLSHDVKTPL
                     ASLVGYLEAVESKIVVGEEKDEYIHVASNKAHYLKNFVENLFEWVKLDSKEQVFHFDI
                     FDLNELSRNIISDWIPVLESSHFEYEFDIPEIEYFLRIDANAYTRIINNLLQNIITHS
                     SGNKMTLRIFENKEQAQIIITDNGKGISSDNLPHIFERLYQCDHSRASKGNGLGLAIA
                     KELINAHKGNITANSTPGMGTEFTILLPKAL"
     gene            13362..14285
                     /locus_tag="JAM15_15285"
     CDS             13362..14285
                     /locus_tag="JAM15_15285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6799615.1"
                     /translation="MNDFVIETKQLTKIYGNQTVVDKVNLHVKKGRIYGLLGRNGAGK
                     TTIMKMILGLTSITYGEVDVFGENIKGCEKRVYPRIGAIIETPGFYPNLTGTENLEIF
                     AKLRGTAAPNSVKRALEIVGLPYKNKKLFSKYSLGMKQRLGIANAILHDPELLVLDEP
                     TNGLDPIGIAEMRKFIRDLSVEHGKTILISSHILSEISLLADDIGIIDHGVLLEESSM
                     SELEKKNSKYILLQVSDIPKTSLILERQFNTKDYSVQDDHTLRLYNTTLDMGEINKAL
                     VMQNVTVISSQLCNDTLEDYFKKITGGEGIA"
     gene            14278..15015
                     /locus_tag="JAM15_15290"
     CDS             14278..15015
                     /locus_tag="JAM15_15290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005945158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6799616.1"
                     /translation="MLKLIQTEFLKLRRRKLIWLMLLSALIMPFFALLYFNYFGKTGV
                     EPTKFYKWSAFGYTLWIILPVVLGIFCTMLIHEENQYDMLKQLWIVPISKMGYFFSKF
                     FVVLIYSICFMLITAVASVLFSVLSGYVVFSWASILYLLKKCLEIGVITAFVMLPILA
                     IATSQKGYILPICITLVYAFSGFVIMTINMYLHPLSSMGVIIMRNKDIPGLIFSQEIN
                     VPLAFLCICIWSIVSVLFANIALGRRK"
     gene            15026..15799
                     /locus_tag="JAM15_15295"
     CDS             15026..15799
                     /locus_tag="JAM15_15295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007060964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6799617.1"
                     /translation="MWKLLWAECQKIRRSKIVWITVFASIMIAVIVFAGGQDVYNDPD
                     LHYGLKSVYDGSRYIDNAGWYMDAVQPWSTFFVLPAVIALLGSYIICREEEEDTIKSL
                     RLIPINETKLTIAKMIITFIFSILLYLLLFTITFLTESVLHFSDLSTKLVLSCMKEYF
                     LDGIGVFFAISPIIALVSRMKKGYWLALAFTEVYSIAGLFAGMSNVLQTFFPIAAIFN
                     ISGYYITTGEKIMGSIISLLLCACLSAFILKGLKHNEKN"
     gene            complement(16340..16948)
                     /locus_tag="JAM15_15300"
     CDS             complement(16340..16948)
                     /locus_tag="JAM15_15300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HAT6799618.1"
                     /translation="MSVINSFILQYGLISVFVLIMIEYACFPLPSEVVLPLCGAIAAR
                     NHFGFLTILILSIIAGILGSIFCYTVGNWGGKSIINKIIEICPKAKKGIFASQDYFNK
                     YSSISVCVCRLIPLCRTYISFIAGIAGQNIITFVISSIVGITIWNTSLISIGYIFSES
                     WVRIMSHYNDYKFLVLIIPISIIFIGFVIKSFIHKKHHKIRL"
     gene            complement(17126..17242)
                     /gene="rrf"
                     /locus_tag="JAM15_15305"
     rRNA            complement(17126..17242)
                     /gene="rrf"
                     /locus_tag="JAM15_15305"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(17362..>17448)
                     /locus_tag="JAM15_15310"
     rRNA            complement(17362..>17448)
                     /locus_tag="JAM15_15310"
                     /product="23S ribosomal RNA"
BASE COUNT         5620 a         3040 c         2205 g         6583 t
ORIGIN      
        1 ataaacaatc ataataaaat ttttttaata aaactttatt ttttagttaa aatcatacaa
       61 tatatagctt tccacaatac aaataaatta aaaagtgaaa tgtatttgtc taaaaacata
      121 ataacatttc actttatcct catttttaag taatatatat ttttaatttt tatttataac
      181 taaatctagt ttttatataa gttttagttt ttttctacat ctgagtaatc tattccaaaa
      241 gtttctacag taacagactt cataatttgt ggagtttgtg gcttatcagc tgaatctgtt
      301 ctaactgatg ctatttcatc aactgtatcc ataccttcta tcactctacc aaaacctgca
      361 tactgaccat ctaagtgtgg tgagttttta tgcattatga aaaattgaga accagctgaa
      421 ttaggtgcca tagttctagc cattgatatg actcctcttt catgttttaa attgttagta
      481 aatccattac cactaaattc accttttatt gagtgacctg ggccacccat tcctgtacca
      541 tttgggcatc ctccttgtat cataaatcct ggtattactc tatgaaatat tattccattg
      601 taatatcctt catttactaa tgatacaaag tttttaactg tatttggagc tatatttgga
      661 tataactcaa ttttgatttc ttttccattt tccatttcta tagttactat aggattttta
      721 ttttccataa tttattacct tccttttcat tagttaaatt acataattac atttattata
      781 ttatactcta aattaaagtc tatcaagtat attttttcct atttcgtatc cttcttgata
      841 aatagtttta caaaactcat catcaaagtt aagcgtatct ttaggagcaa attgagtatt
      901 aggtctaact actattattt tatcttcatc atatactttt ttaatatcct ctggcaactc
      961 ataattatat tttgtggata ttaaaataat tttatccaca ttatccccaa ttaatggttc
     1021 aattaatgca ctcctaatta aacctccatc taatttgaaa ccatcataaa ttccttcttg
     1081 cacatctttc acaaattgtt ctttaaatcc aagagttgcg tttggatttg atggtaacaa
     1141 cccactgtat gaaatgctga taatggcttc attacgaggc atttttgata cgtcaacaat
     1201 cttttctgat actactttat tatcaacttc aacataatta acataaaagt tcatttcttc
     1261 tatattacta tcatctagtt cccttaggtt gtctatagca ggagaattat ccacagtatt
     1321 atttactatt tttacatttc cattctggat atcttttata tttgtccaca ttttctccaa
     1381 gttatcaaca ttccctgtgt acaaataata tccatttatt gctcctattg atgtccctga
     1441 aatcgaataa aatttattta ttcctccatc atacaaggct ttaactactc ctgcttgata
     1501 agcccctttt gctcctccac cttctaaaca taatcctaat ttcatagtct catctccaaa
     1561 ttgtttatct tatatttata tttcaaaaaa cttactaaat gttttatata tactatagtg
     1621 gtcctcaaca tttcctaatt ctcttataga gtgcattgct aaaattggac ttcccacatc
     1681 cacagatggt atatctatat gagtagaaga tattggacct atagtacttc ctcctctttc
     1741 atctgaccta ttaacaaatt cttgatactc aacattagct tctctacata tatttttata
     1801 aatagctata gaatatccat cactagtata tgcctgacta gcatttatct ttataactgg
     1861 accttttccc attattggtt tattagttgg gtcatgcttt tctggaatgt ttggatgaat
     1921 agcatgagct aaatctgatg atatcataaa agatgaataa atagactcaa agaatccctc
     1981 tctatcctta cccattgata tgcaaattct ctccaatata tttaacaaca tgtttgaatc
     2041 tgcaccttgt ttagtagagc taccaacttc ttcattgtca aatacagcca ttacatttac
     2101 accatgttga cctttagtat taacaagagc attcaaacta gcatgtacca ttgcaagatt
     2161 atcttgtctc ccaatagata taaattcatc attagcccct attaaacttc ctttttcaaa
     2221 ttcatataaa aataaatcaa aatctataat atcttccata tttacatcta agttagatgc
     2281 tatttgcttt ataagaaaat tatctttttc taatgtatca tttaacatcc caactaaagg
     2341 taacatatct ttttgcttat tatatgaatg accatcattt atacttctat ttaaatgtat
     2401 tgctagattt ggtattatac aaattggctt tttaaagtct ataagccttt catttggttt
     2461 taatatacta tcacctttta aaactactct accagctatc ccaagaggtc tatccaacca
     2521 tgtacttaat attgctcctc catagcattc tgtatttaac ttcaaataag atttttcagc
     2581 ttctatttct gcatttggtt taatactaaa tgtaggagaa tctgaatgag agcctattat
     2641 tctaaatcca tctctttcta tatcttctga atttactaca aaagctacta tagctgatag
     2701 attcttagta acataatact ttccaccaac tcttagattc catctttgat tcaaaactaa
     2761 ttcttcaaat ccatttttat ctaagatttc cttagtactc tcgactgcat gaaaagacga
     2821 cggactatca tatatgaagt ctattaagtt tttagcaaag tttatactat ccattcctca
     2881 tttacctcca ttataaaata tttagtgttg tatattcttt atttattttt ttaattccct
     2941 gttggtcaaa agctatagta acatctgtac caattataga aaccactgtc ccaaccccaa
     3001 atttaggatg atgtacctta gaaccaagtt ttatatcatc tggattagtt tctttattag
     3061 aatcttttat tgtagcatta actttatctg caactttaga tttgcttata gtactcatat
     3121 actttttagt atatttatct aacatattat aacttgcttt agaatagctt agttcttttt
     3181 ttactttgta caatctttct atacattctt ctggcagttc ttccataaat cttgaagcta
     3241 ttgcaacatt tgttttacca tataatgttc tcttctctgt caatgacata tatagctctt
     3301 ctttagctct agttatacca acataacaaa gtcttctctc ttcttctatt tgtgaatcac
     3361 tcatagattt tatagctctt gatataggaa ataacccttc ttccatacct gttaaaaaca
     3421 caacagggaa ctctaaacct ttggatgtat gaattgtcat aagcgaaacc ctatcattgt
     3481 cttcttcatc atttgattca gatgtaagtg ctatacttgt taggaatgtc tctaagtctt
     3541 tattttcata agtatcatca ttactacttt caaactccaa agctatagaa ataaattctc
     3601 tcaaattatc aattctgtct tgagcttctt cacctttgcc tgttaaatct ttttcatttt
     3661 tatttcttat ctctacaagc tcgtccatat atcctgtagt atccaagact ttttctataa
     3721 gtttgctaac aggataaact tcttttatag ttctaagagt ccctataata tcaacaaatc
     3781 cacttatact tgcccttgcc ttagtagata tatctgaatt tgtttctata tcaattaata
     3841 ctgagtatat actttcctgt tttaagttag ctctatcttc aattttttct atagttctaa
     3901 gccctatacc tcttctagga acatttataa tcctttttat agatatatca tcttgtggat
     3961 tttgaataac tcttaaatac gccaacaaat cctttatttc ttttctctca tagaattttg
     4021 taccaccata tatattgtat ggaatttgac ttctatttaa agcgtcctct acaggtcttg
     4081 cctgtgcatt tgctctataa agtactgcaa aatccttata aggtctattt tcttttctag
     4141 ctatttgtgc aattgaatca gcaatgaaat cagcctcttc tatttcgcta ccagttaatt
     4201 gtatctttat aagttctcct tctttttttt cactccaaag cttttttctt tttctttcta
     4261 tattattaga tataacttta ttagctgcat ctaatatcac ttgtgtagac ctataatttt
     4321 gttctaactt tacaacatgt acattgtcat aatctttctc aaattcaagt atgtttctta
     4381 tatctgcgcc tctccatcca taaatacttt ggtcatcatc tccaacaaca caaatatttt
     4441 gatgttctct tgctaataat tttatcaatt catattgagc tttacttgta tcttggtact
     4501 catctaccat tatgtatcta aatctacttc tgtaatatgc taatacttca tcattagcct
     4561 tgaaaagttc tacagtttta agtattaaat catcaaagtc aagtgcacta tttcttttta
     4621 aacggtcttg atataacgca taaatatctg caatcttaac cattctatta tctgccatgt
     4681 tgatatcttt aaactgcttt ggagtataaa gtttgtcttt tgctcctgaa attgcactta
     4741 taactgcttt tggttcaaac actttatcac ttaaatttaa ttcttttaga cagtctttaa
     4801 ccaatgtaac ttggtctgct gaatcataaa ttacaaaact tctattgtaa ccaatcttat
     4861 ttatatcttt tcttagtata cgaacacagc aagaatggaa tgtacttatc cacatatcct
     4921 tagtttcagg acctatattt tgttcaactc tctctctcat ttcatttgca gctttgtttg
     4981 taaatgttat agctaatata tttggtgctt gtacaccttt atcttctata agatatgcta
     5041 ttcttgttgt taatacctta gttttacctg aaccagcacc agccagtata agtactggac
     5101 cttcagtctt ttctactgct tctctttgag caggatttaa tgtatctaaa ttcatatttc
     5161 tcctcctgtt aacagccata aatatatttt aatctaaaat atgaattact tcaaattata
     5221 attatgtatt atattaatag attatttcca atatattaca attaaataac atttttccat
     5281 ataatttatt tcattgttta ataaaaaaaa taaccttatg atttggggaa tcataaggca
     5341 cctttaaggg gtctaggtta agggttatta tatataaatc tattttttta aaataggttt
     5401 agggcttaat tatttatttg tattaagttc tctttccttc cagtacttat acaaatcttc
     5461 ttctttctta aataagggta aattcatatt tctatgtact tttactaacc atggggattc
     5521 tagaccagct tgtataatat tattttcatt tataaacaca ttttctgcct ttccttcatc
     5581 aatcaaaatc cccttatcca atacatatat gtaatcacat atttcataca ttaaattcat
     5641 atcatgactg gatattacta tttttatatt atttttattt aatcccttta ttatatctac
     5701 aatagaccta gtacttactg ggtctaaacc agctgtaggt tcatcaagta atacaatttc
     5761 attttccatt gctataactg atgctattgc cactcttttt ttctgtccat agctaagaaa
     5821 atgtactggc ctgtctataa aatctattcc attaacagct actagagctt tgtttattct
     5881 ctctttaatt gttttttcat ccataccaat gtttctcatt gcaaaggcta tatcatcata
     5941 tacttttgaa taaaaaattt gtttttctgg gtcttggaac acaataccta cattttttct
     6001 aaggttgtat aaacttctct tatcatattt taacttttct tctttaaaaa gaatttctcc
     6061 agatgtaggc tttaatatac ccattaaatt cataaataat gttgattttc ctgaaccatt
     6121 tgaacctatt atacctataa catttccctt tgaaaaatcc atattaatat ttaatagtgc
     6181 attggtattt ttttcatatt gatacgttaa attatttatt ttaaacatca ttatccccta
     6241 ctatgtgaaa tttaccatca tacaatttta tgtctaatga tatacacata tcatcatacc
     6301 ttgtcataag tcttttgtac agcatacttc caagaatacc taaggattta tatgaagttt
     6361 ttaaatttat atacccaaat cttagctctt gtgacttgta tatttctgaa aattcttcta
     6421 aaaatatgaa tataaaccta tatattaaca ttgatagctc gacaaaagtg tcaggtaaat
     6481 gaagtttttt aaaaaagaat attaattgat taaaaggtgt tgtaagtata caaaaataca
     6541 cacaagtcaa acaagacatc gctctaaata acacatgaat agacatgtca atagacgcct
     6601 ttgatattcc tacattaaaa ctaaaaaatt caaaactata taataaatct gctttattaa
     6661 aagatatatt tacaagagtt attcctatac tgagaaataa aaagtacatt ggtattctaa
     6721 gtaattttaa ataatttttt aaatctattc cagccacaca aacaaccaaa atactcatta
     6781 aaatcataat tccacttaaa ataaatatat tttgtattac catagaagca atcagaaaaa
     6841 ttactcctat ggctactttt ttgtttggat ttactttact caatctattt gtatatgcat
     6901 atttatcaat tataagcatg attaacttct ctttcctttt tgaagaccta atatgtatcc
     6961 tattacacca gcccctaaag ctgcttgtgc agagaataat aaactttcta tttctccact
     7021 tggtggctca tatggactgt taaaccatgg tttgtaattt ggatttatct tagtaatttc
     7081 actttcagct tgaccatctg ctcctccata ttcagcacct gagttgacaa gtagtgggaa
     7141 tataataaga gctactacta ataaaagtaa taatatgtta gtttttgttt ttgttttagc
     7201 actcattagc tttaactcct ttatcattat tttctagtat gcttttttct ccgttttctg
     7261 taattaaatt atatacaatt acagtaagaa taccctctgc tattgctatt ggtatttgag
     7321 tcataaagaa aattcctaaa aatttaattg ctgaagccat taccccacct gatgggtctg
     7381 ggaaagccag tgctaattgt attgaagtta ttgtatatgt ggctaagtct cctattgctg
     7441 ctgcaagaaa tactggaata gcattatttc catctttttt ctttaaagcc ttaaatatta
     7501 ggaatgatac gattggtcct attatcgcca ttgaaaaagc attagctcct aaagtagtta
     7561 ttcctccatg tgctaataac aatgcttgga atattaaaac tatagttcca agaacaaaca
     7621 ttacgcttgg tccaaacatt attgctccaa gacctacacc agtaggatgt gaacaacttc
     7681 ctgttactga aggtattttt agtgctgata atacaaatac aaatgctcca cataaagcta
     7741 ataatacttt ctttttaggg tcttgcttta ctattttacc tattgatttt aatccgaata
     7801 agaaaaatgg tataaatata actccccatg ctatagacca ttttactggt aagtaacctt
     7861 ccattatatg cattgcattt gatgtagctg gagttaaaat gattaacata agtgcagcta
     7921 taacccctaa tttaatattc tgtttcatct tagtatccct ctctcccttt ctaataatta
     7981 aaacataata atacatgtct gatttattta ataaaataaa aaagcctaac tcgatggtta
     8041 ggcttctaat tttccacaat ctaaatacaa acacataaaa caaacatatc tgtataatta
     8101 ttataagaaa ctttctccat ccccgaagaa attactttaa tattttaggc aggtctcctg
     8161 acttagcttc ttcctactcc tcttccttcc catgagatat aaaaaatatc atcatagtgg
     8221 ctaacaaaag tttcgtctgc atcacagtag cgggggctgt aaaggaattt aacctttttc
     8281 cctattaatc ttgcttaaag aacctataat attatatatt taatttttaa attattctta
     8341 aatcattttc tatataaatc attgtatacc ttttctgtga aaatttctac attttttata
     8401 aattttattc atttttatat ttttatgtat ataaattctt ttttgtaagt ttattaattt
     8461 ctaattatct tctttaaata cattgaaact acatcagaaa atctagttat atctcttgaa
     8521 tatataaaat catttccata tattaatctt tcagcttcaa gttctgattc ttttcctgta
     8581 aatactccta gtactaatat attttgcttt ctagcttttc tcacttcatt ggctgtatct
     8641 ctcaaaccaa ctatacccct ataagccttt tctcctctta atgttctctc actacttttt
     8701 cctatcttta catcatttgg tcttccatcg ctgagaacta tcaggatttt attttcttca
     8761 tctctattta ttagaccact acatatagat tttattgcca aaccatctct attattacca
     8821 gcacaaaaat attcaaatat attttcacta ttttttatac tatcatcata atctttaaat
     8881 ctttttaata ttgtatagtc taaaaaacta gaaaatccca tcactctatt tggtatgcca
     8941 acttctgtta gagcatttgc aattatgtaa gcttgaattg ccacatttcc ctgatttcta
     9001 ctttgagagc cacttgcatc caataatata tcaataacgt atttcccttt ttcattttct
     9061 atatctttat aaaatatttt attattatta cttctaccaa ctctccaagc tctatttgct
     9121 aatatagtac cacaatcaga atatactcta cttttagcat tttcttctat taaaattctt
     9181 gacagacttt cttttaatct ctttatttgc tgtctataca ttctagcatg ttctctaaat
     9241 tttcctaaat tattttcttt ttgtcttgtt acatatttta gttgaaatac attattacac
     9301 tcacttctaa gaactccatc tgtaaagtgt attctacaac cttcatgaac atttctacaa
     9361 ttttgtgtct caattttttt aatttcacct ttactcaaat aagtttttcc ataataatgt
     9421 tctatttttg aatatatctt atttgcagtg tcttcatcaa catatataac tcggtctgct
     9481 gaattgctac atttagaatc atcaaaatcc cctacacctt ctacaagcat ggatgaagat
     9541 attgaatcta tatcactttc aataatattt tcttcttcat cactataaag ttcttcatac
     9601 atgaaatcag caaatgtatc aaaatttact tctacacttt ctacattatt ttcatcaata
     9661 agactatttt cttctccatt taatatgtat tcgaaataag ttaaatatat aacatctaat
     9721 gcttttaaaa tctccatcat atcttgattg gtatctatat ttcttatatc attaactatt
     9781 cttctagtca tactatctaa tgctgggtgc ttgtccatat tataaagtac aaatgtgtat
     9841 ttaattttat ccataatatt atcattgtgt attttggtaa aacgtgaaac aatatcttta
     9901 taagcatttc ttcttatgtc ttctatccct ggcctatctt taatgacctt ttcttcaact
     9961 attgtattta atataacttg aattagaccc agtataatat ctttgttgta tccttttctt
    10021 attctatttg taagatattt tttaactata tcccaatcta catactttct tctagcacct
    10081 gcaattattg caaaatatag acctatttct tttgaagagt aatctttttc tgatatatct
    10141 atactttcat tgtaatcacc agctattgtc catgataagt tattagctct attttcaaat
    10201 tcataatcat catatatcca tttcataatc tcacctatat taaatatgac ttattggaaa
    10261 tacatctata ctctcccatt tattaggtat tctagtttta attacatctc caaccatttc
    10321 tttctcatat acatcaaaag tctttcctgt aagtcccata ttaattgcaa gagttggttt
    10381 taatcctctt cttatagtct taagagatgc cataagacca cgtaaatcaa tagctttact
    10441 agatatctct ccattttgag acttcaattg taaatctaaa aatattcctg caaagtgtat
    10501 taatttttct tcatcagcat ctgaaaattc attttttaaa atcatcatta acttatcttc
    10561 ttctatagga ggaatatcta ttaccataaa tctagatacc agtgcttcat taagttcttt
    10621 tgttcctgca tattcataat tcatagtccc aataaatctt gttgctggat gtagattgac
    10681 tctctcatac ccaggtacat caattattct tctatagtct aaagctgaat gtaccacaac
    10741 tatagcatca ttttttgcca tattaatttc atcaaatacc ccaaaacctc cattaatagc
    10801 acactcataa actgagcctc ttctaagttt aacttcattg tctataaatg tatctgtacc
    10861 tataagtgtt gaactgtctg tatttatatg aaatgatgta ttccactgag gtctattaaa
    10921 tatttcccct agattatcag caagtaaatt ttttcccgtt gcctttggtc ccgataataa
    10981 tatattttct tcttctaaaa tagctgctat acacatagac aagatatctt taccataaaa
    11041 ataagtttta gactttgtta ctctgtattc taaatctttt tctaaaccat aataatttct
    11101 aaaatacagt acatcttcaa taagtttttc atctacccct tgcaccctta gattatctat
    11161 tatatccata tttttacccc ttttatataa atagtatttg tttcatttct tatcaccatt
    11221 ttagcataaa aggatataag ctaaaattga ttttttaatc tcccccattt taagtaaaac
    11281 catgcaccat tttatcacta caaaattaag agtactactt actgatattt cttgattttg
    11341 ttcgtctata cgtatataat atatgctgat aaattatgag gaaaggatga ttgaaatatg
    11401 gaatatatgt cttgcccaga agtagcaaaa aaatggggca tttctgaaag aagagtacaa
    11461 aaactatgtg aagaaagtcg cataccagga gtttcaaaac tcgggtatat gtggctgata
    11521 ccaaagaacg cagaaaagcc tgttgatggt agagcaaaaa gaagaaagga agtacaatat
    11581 gaatagcgtt ttgattatag atgatgacaa agaactttgt gctcttatga aaaaatgtgt
    11641 tgagcaagaa aatttatctg ctattactgc acattgtggt gcagaaggtc tacatttgct
    11701 cgataaaaat agacacacac tctctcttgt aattttagac ataatgatgc cagatataga
    11761 cggttttcaa gttctgaaaa aaattagaga aacaagtaat attccagtaa ttatgcttac
    11821 tgctaaaaat gacgaggatg ataaagtttc cggactacgt ttaggtgctg acgattacct
    11881 aacaaaaccg ttcagcataa acgaacttat ggctcgtgtc aattctctta ttcgtcggta
    11941 tactatgtta aaccctgctt ttataacaga cacagattgc ataataataa atggcatgat
    12001 tattgacaag acaaaccgaa ttgtttctat caataatatt cctgttcaac ttacaagcaa
    12061 agaatttgat ttacttgctt ttctggcttc taataaggga cgggtattta ccaaaaaaca
    12121 gatttataca caagtatggg aagaagaata tgcttttgac gatagtaaca tcatgtcttt
    12181 catcagtaaa ttgagaaaaa agattgaacc agaccccaac catccatttt atattttgac
    12241 agttcgtggt gtcggttatc gttttaataa ggaggcttaa catgaataca agtgtctatc
    12301 tacttttgat attggctctt agcctgatta ttatagcgta ccttgtttct gtcctgctac
    12361 gtgtccgaat acaacttaca cttataaaag atgctttaga ggatataaaa aatggaaacc
    12421 ttaatcgccg tattttaaca gatgaaaacg acattacaaa acaaatttgc tatgatatta
    12481 acgaaatagc aatcaatagc caatttcaac ttattcagca aaaacaatca gaacaagcct
    12541 acaaacagct aatgacaagt ctctcccatg atgtaaaaac tccactcgct tctttggtcg
    12601 gttatttgga agcagtagaa agtaaaattg ttgtaggaga ggaaaaagac gagtatatcc
    12661 atgttgcgtc taataaggct cattacttaa agaattttgt agaaaatcta tttgaatggg
    12721 taaaattgga ttctaaggaa caagtttttc attttgatat ttttgacttg aatgaattat
    12781 cccgtaatat tatatctgat tggatacctg ttttagaaag cagtcatttt gaatatgaat
    12841 ttgatatacc agaaatagag tacttcttac gtatagacgc aaatgcatat acccgtatca
    12901 ttaataacct attacaaaat attattaccc atagtagtgg caacaaaatg acattgagaa
    12961 tttttgaaaa caaagagcaa gctcaaatta taataacaga taatgggaaa ggtatatctt
    13021 cagacaatct cccacatatt tttgaaaggt tgtaccaatg cgaccattca cgagcttcaa
    13081 agggaaatgg tttaggcttg gcgattgcaa aggaacttat taacgctcat aagggaaata
    13141 ttaccgccaa cagcactccc ggtatgggaa cagaatttac aatattgctt cctaaagccc
    13201 tgtaaaagta cgaggctttc ttactctaaa acaagataaa agcaagatta tggcaaggtt
    13261 ttggcaaggt tcatgtttta taattctaat tgtagttgat tttgacgttg tatcaactat
    13321 cttttgtaga aacaaattta ttaaaagtga ggaaattata tatgaatgat tttgtgattg
    13381 aaacaaagca acttacaaaa atttatggga atcaaacagt agttgacaaa gtcaatctcc
    13441 atgtaaaaaa aggccgaata tatggtctgt taggacgcaa cggagctggg aaaaccacaa
    13501 ttatgaaaat gattttagga ttgacttcaa tcacgtatgg cgaggtagat gtatttggag
    13561 agaatattaa gggatgtgaa aaacgagtat atccccgtat cggtgcaatt atcgaaacgc
    13621 caggatttta tcctaatctg acaggaacgg agaacttgga gatttttgca aaacttcgtg
    13681 gtacagccgc ccctaattct gtaaaaagag cattggagat tgtaggctta ccttataaaa
    13741 ataaaaagct gtttagtaaa tattcacttg gcatgaaaca gcgacttggt attgccaacg
    13801 ctatcctgca tgacccggaa ctgttagttt tagatgagcc aaccaatgga cttgacccta
    13861 ttggtattgc ggagatgaga aagtttatta gggacttgag cgttgagcat ggaaagacaa
    13921 ttcttatctc cagtcatatt ctttcagaaa tctcattgtt ggctgatgat attggaatta
    13981 tcgaccacgg tgttcttttg gaagaaagta gtatgagtga actagaaaag aaaaacagta
    14041 aatatatcct gctacaagtt tcagatattc caaagacatc acttatttta gagcgtcaat
    14101 ttaacacgaa ggattattcc gttcaagatg accacacttt acgcctttat aacactactc
    14161 tggatatggg tgaaatcaat aaagcacttg taatgcagaa tgtaactgtt attagttctc
    14221 aactttgtaa tgatacttta gaggactact ttaaaaaaat cacaggagga gagggcattg
    14281 cttaaactta ttcaaacaga atttcttaaa ctgcgtcgta ggaaacttat ttggctgatg
    14341 ttgttgtctg ctctcattat gccgtttttc gcactactat acttcaatta ttttggtaaa
    14401 acaggtgttg agccaacaaa gttttataaa tggtctgcat ttggttatac actttggatt
    14461 attttgcccg ttgttttggg tatattttgc accatgctta tacacgaaga aaaccagtat
    14521 gatatgctca aacagctttg gattgtacct attagtaaaa tgggatactt ttttagtaaa
    14581 tttttcgttg ttttgattta ctctatttgt tttatgctga ttacagccgt tgcttctgtg
    14641 ttatttagtg tactttctgg atatgtcgta tttagctggg caagcatttt atatttgttg
    14701 aaaaaatgtt tagaaattgg tgtaatcact gcttttgtaa tgttgccgat tttggcaatc
    14761 gctacatctc aaaaaggata cattctccca atttgtatca cattggtata tgccttttcc
    14821 ggttttgtta taatgacaat aaatatgtat ttacacccat tatccagtat gggagttatt
    14881 atcatgagaa ataaagacat tccaggtctt atattttcac aggaaattaa tgtcccatta
    14941 gcatttcttt gtatttgtat ttggagtatt gtatcagtat tgtttgcaaa cattgcacta
    15001 ggaagaagaa agtgaggtgt atataatgtg gaaattactt tgggctgaat gtcaaaaaat
    15061 tcgtcgttca aaaattgttt ggattacagt ttttgcatcc attatgatag cagtcatagt
    15121 ttttgcagga gggcaggatg tatataatga cccagattta cattatggct taaagagcgt
    15181 ttatgacggt tcacggtata tagacaatgc aggttggtat atggacgcgg tacaaccttg
    15241 gtcaactttt tttgttcttc ctgctgtcat tgccctatta ggaagctata ttatttgtcg
    15301 tgaagaagag gaggacacta ttaaatccct gcgtcttatt cccataaatg aaacaaaatt
    15361 aaccatagca aaaatgatta ttacttttat attcagtata cttctttatt tgttactctt
    15421 tactataaca tttttgactg aatccgtttt acatttttcc gatttatcga caaaactggt
    15481 tttaagttgc atgaaagagt attttcttga tggcataggt gtattctttg caatttctcc
    15541 cattattgcc ttggtatcgc gcatgaaaaa aggatattgg cttgcattag cattcacaga
    15601 agtttattct attgctggac tatttgcggg tatgtcaaat gtcttacaaa ccttttttcc
    15661 tattgcagca atatttaata tttctggata ctatataact actggagaaa aaattatggg
    15721 gagtatcata agtttattac tttgtgcctg cctttctgca tttatactga aagggctaaa
    15781 acacaatgaa aaaaattgaa ataggtatat caaaatgaaa aagataaaaa aactgattat
    15841 tctaattgta ttcttgtttc tttttggcat gttacactgt tatactgaat ggaaattcaa
    15901 caatgaccca cctaaagggg taatagaaag aataaatgag tggactgata agattggact
    15961 ggattagtaa cttatgttaa ttatagtgaa tgtaatatta gcaagttatt gtttcgtatt
    16021 ttaatactat aactttaaat atttgatttt aatcttccga acgaatataa aaaaactgtc
    16081 acagaggcaa catatttttg aatatttata aagtggtagt tttgattttc aaagctgccg
    16141 ccttttcttc tatataagca aacttatcct caacaaagtg taaaacatgg tacattttaa
    16201 gaaaaaagta ccacagacac aagcaataaa agaaacgccg agaacctaca aaaacgtagt
    16261 gcttatgcag atttacgacg ccttctattt tctcaaccgt cttaatgacc ttgtacaaaa
    16321 gaaatttttc taatattttt tataatctta tcttgtgatg ttttttatgt ataaatgact
    16381 taataacaaa tccaataaaa attatggata ttggtataat tagaacgagg aatttataat
    16441 cattataatg tgacattatt cttacccaac tctcagaaaa aatatatcct atactgatta
    16501 atgaagtatt ccatatggtt attcccacga tagatgatat tacaaaagtt ataatatttt
    16561 gacctgctat acctgctata aaagatatgt atgttctaca taaagggatt aatctacata
    16621 cacaaacaga aatagaagag tatttattaa aataatcttg agatgcaaat attcctttct
    16681 ttgcctttgg acatatctct attattttat ttatgataga tttacctccc caatttccca
    16741 ctgtataaca aaatatcgaa ccaagtatac ctgcaattat acttaaaatt aaaattgtca
    16801 gaaatccaaa atgatttctt gcagcaattg ctccacataa aggtaaaaca acttcgctag
    16861 gtaatggaaa acaagcatac tcaatcataa ttaatacaaa tacagagatt aatccatatt
    16921 gtaaaataaa actattgatt acagacactt acttatctat ctcctttctt atttaaaggt
    16981 tttaagggta catattctaa ggattctcac cctatattta aagaatcaat ctctttaaac
    17041 tattatatgt atttacacaa agcatttata acatacttta aaaatagtac cttaaaataa
    17101 gaaacttaat aaataaaaaa agattacgtg gctacgtcct actctcccag gcagtttccc
    17161 accaagtacc atcagcgcta gagagcttaa cttctgtgtt cggaatggga acaggtgtat
    17221 cctctctgct attgtaacca cataatcttt atgcttaata tttctattaa gtttttaata
    17281 agtttataga acctagtaat actagtttct ttagagttag cactctaaaa actacacata
    17341 tatcttaatg aatgaacatc aaataaatgt tggtcaagtc ctcgacctat tagtatcgat
    17401 aagctaaata cattgctgca cttacacctt cgacctatca accagata
//
LOCUS       DACTZW010000086        17348 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.086, whole genome shotgun sequence.
ACCESSION   DACTZW010000086 DACTZW010000000
VERSION     DACTZW010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17348
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.086"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            50..460
                     /locus_tag="JAM15_15315"
     CDS             50..460
                     /locus_tag="JAM15_15315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAT6799619.1"
                     /translation="MNKKKILVPIDGTERSMHSLEFIKGIFKKDEVEVEIMNVKELVF
                     IDGISLAEEIKNSENLGRRILDKAAEIMGEYDVKVHFTFGYPGDEIIRKAKEDNVDFI
                     VMTKSTKKGLTRMIGSVTASVVKQAKCIVMIVPE"
     gene            482..784
                     /locus_tag="JAM15_15320"
     CDS             482..784
                     /locus_tag="JAM15_15320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIBC"
                     /protein_id="HAT6799620.1"
                     /translation="MNKKIVAVCESERSLNSLKTAANDLGFDLVYEIQENDNIKNELS
                     IYDIEDVSIVLFVTSDSIESIEKIDRFIDREFYEVDPKYIIEDAKSIVSEILIDLN"
     gene            complement(1000..1692)
                     /locus_tag="JAM15_15325"
     CDS             complement(1000..1692)
                     /locus_tag="JAM15_15325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HAT6799621.1"
                     /translation="MKSLNATEKIIDYIKLNILNGTFKINSKLPSERKIADLFNISRI
                     PVRNAINILCKEGILRAVPYSSPIVEGFKKVDLFDDGEIYKNHNIQEFYVESLRARQL
                     IESEATKLAILNATSKELQKIKYTYLKSIEELDKVSHGLIEECYDADLQFHKEIILAS
                     HNPIFIKYYELIPKTVSSNQYFGFKYRNSLKDMISHHNKIMMAFDSKDSYLGYTSMYN
                     HLEDVIQLFQHD"
     gene            complement(1718..2905)
                     /locus_tag="JAM15_15330"
     CDS             complement(1718..2905)
                     /locus_tag="JAM15_15330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAT6799622.1"
                     /translation="MKKISNQKLLLLSIVTFFWFSQYVYIPFQNPYLSACNVSTNMIG
                     IIIGAYGISQCLLRLPVGVFADSINKHKIFILSGIFFAGLASLIRVFSPGGNGFLIAN
                     ILSGISSSTWISYMVHYTNFFSTEHQQKATSTIILVNNLGMLIGFVMSTLFYEKLGMT
                     ALCIMSVLSSVIGTILALNIKNHNSKKIPEKISIKKYLSICKDKRLVFFSFMALIQQG
                     IQMSTTMSFTTQILKNLGSSSTLIGLSSISYMVCAVASSGFASTKFCTKYGPKFWIPL
                     VFILVSAYCFLVPTIKNINIIFVLQVLPGISTGILLSYLTSESMKNVPKHQKSTAMGF
                     FQAIYAIGMSVFPMIVGKISEYTSIQYGYFILAIIAILASILSYTYYKKVDLTLNYDI
                     IQS"
     gene            3240..5117
                     /locus_tag="JAM15_15335"
     CDS             3240..5117
                     /locus_tag="JAM15_15335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAT6799623.1"
                     /translation="MDYKNIAQEILLNVGGKENVNEVTHCMTRLRFKVKSASKVNKDK
                     LSKTEGVITVVESMGQIQVVIGNKVKKVYDEVIKIVPQSNNVGKKNESQEKQGIINSI
                     LSAVAGIFTPTIPAIAGVGMIKGILSVLAMYYMNKNGVDIKETQSYIILNAMADSIFY
                     FMPIILGYTAAKVFNANKIISMVLGATLCYPTFTALMAGEESVRFLGLAVTKATYTSS
                     VIPIIIAIWALSYVEKVLEKYIPEVIKIIMVPTLSLVVMLPATLFLFGPIGIYIGNVI
                     NFSYKYIYELSPALCGAFVGGLWCVLVIFGAHRALLPIGISDVAQTGRQNLLAFAGAA
                     NFSQAGAALGVFFKTKNQGLKTISMSATITALFGITEPAIYGANLRLKKPMVCAVICG
                     AFGGAIMGMGGAYGNAFANQGVLTIPVYAEAGALGFLSYLGGCAIAFFGSAISTYLVG
                     FEDLEESSNKENSFIKVETKDGVIDITSPVEGECIELSEVKDDVFASKAMGEGIAVLP
                     TKGVITAPTDCEVASLFPTLHAIGLKLDNGAEMLIHVGINTVELNGKYFTKHVNQGDL
                     VKKGDKLISFDIDKIKKAGYDVTTPVIVNNTFDFGQVVSCKSSYVSTNDNIISLVLAG
                     N"
     gene            5429..6835
                     /locus_tag="JAM15_15340"
     CDS             5429..6835
                     /locus_tag="JAM15_15340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAT6799624.1"
                     /translation="MNTGFPKDFLWGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHL
                     QADTKVASDFYHNYEEDIELMKELGMKTYRFSISWARIIPDGEGEINQKGLDFYNKII
                     DKLIECDIEPFVTLYHFDLPFKLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQ
                     PHNEQNLIVRVEERINIYDETDSWKIDKMRAQMDYNLCLAHALAVNACHEMIKESKIG
                     AAVSSSVTYPLTSKPEDVYAARMNDNFKVYYMLDMHHYGEYPGYYMKYLEKRNTVPHM
                     EDGDKEILKKAKMDFIAVNYYRTNCAEALPEDSQHPFGLREGTVDFSMYGLFKMSMNP
                     NLEASEYGAAIDPSGLRVALNEYWQRYHLPVIITENGLGAKDILEDGKIHDDYRIDYL
                     RSHINACKLAIEDGVEMIGYCPWSFTDLLSSSQGFNKRYGLVYINRTDHEVLDLKRIK
                     KDSFYWYKEVIENNGIVK"
     gene            6863..7711
                     /locus_tag="JAM15_15345"
     CDS             6863..7711
                     /locus_tag="JAM15_15345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAT6799625.1"
                     /translation="MYITKVLNNSLLLAKDDNDEEIILMGKGIGHNYKAGSELNKKDI
                     EKIFVLHDENIKKSIIQLATEIDAEYFGIAQMIIAYGIEKYNLKLMNHIYLALTDHIA
                     FAVRRFKEGIMIENHYLFEIKEFNPKEYDIGKYAITVFKEVLGLDLPEEEIGNIAGHF
                     INAQQDNPYSDRNKRSAKIVNAILQIVHYHFSIVYNKESFYYRRFVMHLKAFSQRFLA
                     NEPSREKIDFIYEQVQKNCKEEYECVKKVGAYMYKEYSRELPRQEELYLMIHIHKILG
                     ELCENS"
     gene            8372..9064
                     /locus_tag="JAM15_15350"
     CDS             8372..9064
                     /locus_tag="JAM15_15350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003020373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6799626.1"
                     /translation="MNKVLIIDDDKDLCILLKKSISIEQIEANYCHSGRDGLVELSKQ
                     DYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTSKSDNYSKVHGLRAGADDYLTKP
                     FEITEFTARVLSLIRRYTRFNPKNEEPQQLSFKGLLIDLDQHTVTTNGEPMLLPPKEF
                     GVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQT
                     IKGIGYQFNTEV"
     gene            9061..9996
                     /locus_tag="JAM15_15355"
     CDS             9061..9996
                     /locus_tag="JAM15_15355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAT6799627.1"
                     /translation="MKMDEQTIILFLFLLSIGLLFLSIFAFSKLGHIHKRLKDIEEIL
                     ADVQIGNENRKILIKPCDVMAPLVYQLNEIVYDYENKLLSLKKSDKASKQLMTSLSHD
                     VRTPLTTLIGYLDAVHSGIVIGQEREEYLEIARRRAYDLKDYIDVLFDWFRLNSDEFT
                     LSIESVEIAELSRNILKDWIPIFHEKKLNFEIDIPENRLMVNLDPDGYSRVVNNLVQN
                     VLAHSKARQIKITMSEDSRMVLLRVDDDGVGIARENLPHIFERLYKCDKGRSEKGSGL
                     GLSIVSQMVERMGGQISVESEIGKYTVFTVSLPLI"
     gene            10144..11067
                     /locus_tag="JAM15_15360"
     CDS             10144..11067
                     /locus_tag="JAM15_15360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6799628.1"
                     /translation="MNNLIIETKNLTKQYGAQKSVSNLNIHVQKGRIYGLLGRNGAGK
                     TTTMKMLLGLTKPTTGEIKIFGQDIHNNEKKLLPRIGCLIESPGFYPNLTGTENLKIF
                     ARLRGIPKKNAVESALDVVGLPNNDKKLFSQYSLGMKQRLAIALAIMHDPQLLILDEP
                     INGLDPIGIAEVRKFIRDLCTERGKTILISSHILSEIALLADDIGIIDHGILLEEESL
                     AQLEEKNSKYIHFAVSDAAHAARLLETQLNLKNFKVADNYNIMLYDTDVSVAEINRAF
                     ILNNIEVSESHLCEDTLEDYFKKVTGGEGIA"
     gene            11060..11821
                     /locus_tag="JAM15_15365"
     CDS             11060..11821
                     /locus_tag="JAM15_15365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6799629.1"
                     /translation="MLDIISCEFSKLKRLKFILISILGACLFPIPATILIAKDNLPFE
                     QLFKLVVNFGYFLLLPIVLSIVASQLFFIERDNDVLKNLATVPVPKGKLALAKLAVLL
                     FISLFYSVAGLGATIIGGFIVGIVEGVTVKLGMSIAFGIMFFVTVLPVVVLIVYFNRS
                     YIFSIILSFVYAIFNFSISLNIINFEPNNPLLSVLPAPVIMRWWMAFWGDPTGEYTAL
                     RQPYLLSTPACVGILCLITIIAVLLICMIYKKQEN"
     gene            11831..12613
                     /locus_tag="JAM15_15370"
     CDS             11831..12613
                     /locus_tag="JAM15_15370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6799630.1"
                     /translation="MLDIITTEFQKIKRYNILWIGVVAVLFSALLAVFQVVSSHGSDP
                     LTYESFANGVIWNNFSLSFPFGITLIGGYLINREYTDQTLKNILTVPISLRKLLVGKL
                     IAVGGIAVLLSLFSFLCTFILGLLFCNINISVTLIVKSLVQILSVNLYCYVAVLPIIA
                     YFGRKQNAFLTGVGIAFVYGFCGVFVAGRNLTDFYPITAGLGLVGYNNGAGTVYQPLI
                     GAMTLIVILILTTILLVFTPNYDKVMTISKKKGIKHKKYSHK"
     gene            12987..13526
                     /locus_tag="JAM15_15375"
     CDS             12987..13526
                     /locus_tag="JAM15_15375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004617814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HAT6799631.1"
                     /translation="MMNLKGTKTEKNLMAGFAGESEARNKYTYYASKARKEGYNQIAA
                     IFEETANNEKEHAKLWFKLLHDGMPSTEENLKDAAAGENYEWTDMYAKFAKEAREEGF
                     DKIAYLFEAVGKIEKEHEERYLKLLENLNEGKIFKRDEEVVWQCQNCGHVYVGTEAPE
                     KCPVCDHPKAYFNIKAENY"
     gene            13558..13947
                     /locus_tag="JAM15_15380"
     CDS             13558..13947
                     /locus_tag="JAM15_15380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAT6799632.1"
                     /translation="MKFSKQRELILNEILNNPVHPTADYLYENLKKDNPNLSLGTVYR
                     NLAQLTEHGFIRKVSIPGYPDRFDGRIDNHYHIICEVCGEVYDLESEVLNNLQELISE
                     ETDIKITSYNISFKGICNNCKRCSQVG"
     gene            13984..14370
                     /locus_tag="JAM15_15385"
     CDS             13984..14370
                     /locus_tag="JAM15_15385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="desulfoferrodoxin"
                     /protein_id="HAT6799633.1"
                     /translation="MCSEQKFFICETCGNLVGMIQSGGVPIFCCGKPMKELVPNTTDA
                     AVEKHVPVIEVDGNNVTVKVSSTTHPMTKEHHIAWVYLMTEQGGQRKCLAVDGEPVVK
                     FALNDDDKVISAYAYCNLHGLWKAEL"
     gene            14497..15939
                     /locus_tag="JAM15_15390"
     CDS             14497..15939
                     /locus_tag="JAM15_15390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding glutamate synthase family protein"
                     /protein_id="HAT6799634.1"
                     /translation="MSIYKCSVCGYIYDESKNDKTWDELSEDWECPVCTKGRSYFGKI
                     STVYYEEDEKIAEDIVENESKLNTEKEGDLNYLSTYLRRDDEVEKHMDIIHEMAVTGK
                     SIIEPMRTKLPVISWDDILIMGAQLNPLPLNEHDEVNTTTIIGKKAKKPMIIENPVYI
                     SHMSFGALSKELKIALAKGAAQNKTAMCSGEGGILPEEKEASYKYIFEYVPNKYSVTE
                     ENLKNSDAIEIKIGQGTKPGMGGHLPGEKVTEEIAKVRNKPVGQDVISPSCFEEIQSK
                     EDLKKLIDELREVSEGRPIGVKISAGHIEKDMEFIAYAKPDFVTIDGRGGATGASPKL
                     LKDATSIPTIFALYRARKYIDTHGLDIDLVITGGLRISTDFAKAIAMGADAVAIASSA
                     LMAAACQQYRICGSGKCPVGVATQDEELRKRLHIENSANRVANFLNVSLEELKTFARI
                     SGHKDIHDLSVDDLYTVNSEISNYTNIQHV"
     gene            16236..17051
                     /locus_tag="JAM15_15395"
     CDS             16236..17051
                     /locus_tag="JAM15_15395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAT6799635.1"
                     /translation="MERLKIQVLVDNNTYIDRYFVGEPAVSYYIEIDGNRILFDSGYS
                     DVFISNAEKLNIDLGNLTHVVFSHGHNDHTRGIQFLENRYDLSTVELISHPNCFIPRK
                     HGEKSIGAPFSAEEIKNIFMYNPKDKPFNLSKNCVFLGEIPSINNFEKRAKIGKCKIG
                     DLWEDDYVLDDSAIVCKTDKGIFIVTGCSHSGICNIVEYAKRVCGDDRVIGILGGFHL
                     FELNNRLDSTIQYLDKEEIRMLYPCHCVSFKVKAKMNEILNINEVGVGLTISI"
BASE COUNT         6328 a         2104 c         3174 g         5742 t
ORIGIN      
        1 tttattatat tttatttaat tatcctaaag tgagaaagga agatgtgaca tgaataaaaa
       61 gaaaatatta gtgccaattg atgggacaga aagaagtatg cattctttgg aatttataaa
      121 aggaatattt aaaaaagatg aagttgaagt agaaataatg aatgtaaaag aactagtatt
      181 tattgatggc atatccctgg ctgaagagat aaaaaattct gaaaatttag gaagaagaat
      241 cttggataaa gcagcagaga taatgggaga gtatgatgtt aaagtacatt ttacttttgg
      301 atatccagga gatgagataa ttagaaaagc aaaagaagat aatgtagatt ttatagttat
      361 gacaaaatct actaaaaaag gtcttacaag aatgataggt tcagtaacag caagtgtagt
      421 taaacaagca aaatgtatag tgatgattgt accggagtag aattagaaag gtatttgaaa
      481 tatgaataaa aagatagtag cagtttgtga aagtgaaaga agtttaaatt ctcttaagac
      541 agctgcaaat gatttaggat ttgatttagt ttatgaaatt caagaaaatg ataatataaa
      601 aaatgaactt tctatttatg atatagaaga tgtatctata gtgttatttg ttacaagtga
      661 ttctatagaa agcatagaga agattgatag atttatagat agagaatttt atgaagttga
      721 tccaaagtat ataatagagg atgcaaaatc tatagtaagt gaaattttaa tagacttaaa
      781 ttaatcgtgg gtgtcgcact aagaatagag cgacgccttt ttacatattt tacataagaa
      841 ataaagggct gtctcaaact atagataaga ctctttttca ttgttgaaat gatgaaaata
      901 tatttgattt catacaaaaa agagtgcctc ataactaaaa agttcacttt gagacactcc
      961 atttttatat gttagttgca tttaaggtaa aatagaagtt taatcatgtt gaaataactg
     1021 aattacatct tctaaatgat tgtacattga tgtataacct aagtaagagt ctttactatc
     1081 aaatgccatc attatcttgt tatggtggct aatcatatcc ttaagagaat ttctatattt
     1141 aaaaccgaag tattggttag aagaaactgt tttaggtatt aactcataat attttataaa
     1201 aattggatta tgagaagcta aaattatctc tttgtgaaat tgtaagtcag catcataaca
     1261 ttcttctatc aaaccatgag aaaccttatc caattcctct attgacttta ggtaagtata
     1321 ttttattttt tgaagttctt tagatgtagc atttaaaatt gctagtttag tagcttcact
     1381 ttcgataagt tgtcttgctc ttaaagattc tacataaaat tcttgtatgt tatgattttt
     1441 atagatttca ccatcatcaa ataggtcaac ttttttaaat ccttcaacta taggacttga
     1501 gtaaggcaca gctctaagta ttccttcctt acagagtata tttatggcat ttcttacagg
     1561 tattctactt atgttaaata ggtcagcaat ctttctctca cttggtaatt tactattaat
     1621 tttaaaagtt ccatttagaa tgtttaattt aatataatca ataatttttt cagtggcatt
     1681 taagcttttc ataaaaactc ctaaacatat aattttttta tgattgtatt atatcatagt
     1741 taagagttaa atctactttt ttataatatg tataagacag gatagaggcc aaaatagcta
     1801 taatagccaa gataaagtat ccatattgta ttgaagtata ttccgatatt ttaccaacta
     1861 tcattggaaa tacagacatt cctatagcat aaattgcttg aaaaaaaccc attgcagtag
     1921 atttctgatg ttttggtaca tttttcatag actcgctagt aaggtaagaa aggagtatac
     1981 ctgtagatat acctggtagc acttgtagta caaatattat attaatattt tttattgttg
     2041 gaactaaaaa gcaataggct gaaactaaaa taaaaactaa aggaatccaa aattttggcc
     2101 catacttagt acaaaattta gtagaagcaa agccagaaga agcaacagca cacaccatgt
     2161 aagatataga agatagacct atgagggtag aactagaacc taagttttta agaatttgag
     2221 tagtaaatga cattgttgta gacatttgaa taccctgttg aattaatgcc ataaaggaaa
     2281 aaaatacaag tcttttatct ttgcagatag ataaatattt tttaattgat attttttcag
     2341 gtattttttt tgaattatga ttttttatat ttaaggctag aatcgttcca ataactgaag
     2401 acaatacact catgatacat aaggctgtca ttcctaattt ttcataaaat aaagtactca
     2461 taacaaatcc aatcaacatt cctagattgt ttaccaatat tatcgtactc gtagcttttt
     2521 gttgatgttc tgtagaaaaa aagttggtat agtgaaccat gtaagaaatc caagttgatg
     2581 atgatattcc agataaaatg ttagctataa gaaaaccatt gcctccagga gaaaagactc
     2641 ttataagaga tgctaaacca gcaaagaaaa ttccagacag tataaatatt ttatgtttat
     2701 ttatagaatc agcaaatact ccaacaggaa gccttaataa acattgtgag attccatatg
     2761 cacctattat tataccaatc atatttgtag atacattaca tgcacttaaa tatggatttt
     2821 ggaaaggtat atatacatat tgtgaaaacc agaaaaatgt aacaatagaa agtaaaagta
     2881 atttttgatt agatattttt ttcatattat cctccgtatg gtatttttat aatgcaaata
     2941 atataccatt tagatttttt aatcaagtac tttctctatt aaaaaaaatt taaatatata
     3001 attattattt acaaaaaatt atactttata gttgaattaa gaaaacgctt atgatactat
     3061 aaagttaaca aatttgaata tataacagta gacgtgttac tggtaatgca ggcaagatcg
     3121 aatcaatttt tatagattat ctatagagta ctatgggtat aatctattta tttggttcga
     3181 tttttttgtt taattggcca taaaacaaaa agcctatagt tgaaaatgga ggatttttta
     3241 tggattataa aaatatagct caagaaattc tactaaatgt aggaggaaaa gagaatgtaa
     3301 atgaagtgac tcattgtatg acaagactta gatttaaagt caaaagcgct tctaaagtga
     3361 ataaggataa attatctaaa actgaaggag taataactgt tgttgagagt atgggtcaaa
     3421 tacaagttgt aattggaaat aaagtaaaaa aagtatatga tgaggttata aaaattgtac
     3481 ctcaatcaaa taatgtaggt aaaaagaatg aaagtcaaga aaagcaaggt ataattaatt
     3541 ctatattatc agcagtagct ggtatattta cacctacaat acctgctata gcaggggttg
     3601 gtatgattaa aggtatttta tcagttcttg ctatgtatta tatgaataaa aatggagtag
     3661 atataaaaga aacgcaaagc tatattatct taaatgccat ggccgattct atattctatt
     3721 ttatgcctat tatactagga tatactgcgg ctaaagtatt taatgcaaat aaaataatat
     3781 ctatggtatt aggagctaca ctttgttatc caacttttac tgctttgatg gcaggtgaag
     3841 aatctgttag atttttagga ttggcagtaa caaaagctac gtatacatca tctgttattc
     3901 caataattat tgctatatgg gctctttcat acgttgaaaa agtattagaa aagtatatac
     3961 ctgaggtaat taaaataata atggttccaa ctttatcatt ggttgtaatg ttacctgcaa
     4021 cattattttt atttggacca atcggaattt atataggaaa tgtcataaac ttttcttata
     4081 agtatattta tgaattaagc ccagcgttgt gtggagcatt tgtaggtggg ttatggtgtg
     4141 tgttggttat atttggtgct catagagcat tattaccaat aggtataagt gatgttgctc
     4201 aaacaggaag acagaattta ttggcatttg caggagctgc aaacttttca caagcagggg
     4261 ctgctctagg agtattcttt aaaactaaaa atcaaggact aaaaacaatt tctatgtctg
     4321 caactataac agctttattt ggtataactg aacctgcaat atacggtgcc aatcttagat
     4381 taaaaaaacc tatggtatgt gccgtaatat gtggtgcatt tggaggtgcg ataatgggaa
     4441 tgggtggagc ttatggtaat gcatttgcaa accaaggtgt tttaactata cctgtatatg
     4501 ctgaagcagg tgcattaggt ttcttaagtt atctaggtgg ttgtgctata gcattttttg
     4561 gttcagctat ttcaacttat ctagttggat ttgaagattt ggaagagtct tctaataagg
     4621 aaaattcatt tataaaagta gaaacgaagg atggtgttat tgatataact tcacctgtag
     4681 agggcgaatg tatagaattg tcagaagtaa aggatgatgt atttgcttca aaagctatgg
     4741 gagaaggtat agctgtgtta cctacaaaag gagtaataac agcccctact gattgtgaag
     4801 tagcttcttt atttccaaca ttacatgcaa taggattaaa attagataat ggagcagaaa
     4861 tgttaataca tgttggaatc aatacagtag agttaaatgg taaatacttt acaaaacatg
     4921 ttaatcaagg agatttagtg aaaaaaggtg ataaacttat atcgtttgat atagataaaa
     4981 taaaaaaggc tggttatgat gtaactacgc cagttatagt aaacaataca tttgattttg
     5041 ggcaagtagt ttcttgtaaa tctagttatg tttcaaccaa tgataatata atttcattag
     5101 tattagctgg taattaagtt aatttgacta gagataagta aattgattta aaaggaaata
     5161 agtaaatcaa caattaaata catctaaaag taagtttatt gcaatgaatt gttaaagaaa
     5221 ataattaata tggagtaaag ctattgcaat gaagtaacaa agaaaataat taatatagag
     5281 taagtttatt gtaatgaatt gttaaagaaa ataattaata tagggtaaat ctatctcaat
     5341 gaaataacaa agaaaagagt taatatagag tgaacttatt gcaatgaatc aacaaaaaaa
     5401 ataatcaata taaaaaggag aaatatttat gaatacagga tttccaaaag actttttatg
     5461 gggagcatca tcttctgcat ttcaagtgga aggagcttgg gataaagaca ataaaggaaa
     5521 aaccgtagcc gactataatt cttttaaaaa gtctcattta caggcagata ctaaagttgc
     5581 atcagacttt taccataatt atgaagaaga tattgaatta atgaaagaat tagggatgaa
     5641 aacatatcgt ttttcaattt catgggcaag gataatacca gatggtgaag gagagataaa
     5701 ccagaaaggt ttagactttt ataataagat aatagacaaa ctaatagagt gtgatattga
     5761 gccattcgta actttatacc attttgacct tccatttaaa ttagtagaga aatataatgg
     5821 ttgggaaagt agagaaactg tctatgcttt tgaaagattt gctaaaatat gctttaagca
     5881 ttttggagat agggtaaagt attggcaacc tcataatgaa cagaatttaa ttgttagagt
     5941 ggaggagaga attaatatat atgatgaaac agattcatgg aagatagata aaatgcgtgc
     6001 tcagatggat tataatcttt gcttagcaca tgcattagca gtcaatgcat gtcatgagat
     6061 gataaaagaa agtaaaattg gagcagcagt atcatcatct gtaacatatc ctcttacttc
     6121 taagccagaa gatgtatatg cagctagaat gaatgataat tttaaagtgt actatatgct
     6181 tgatatgcat cattatggag aatatccagg gtattatatg aagtatcttg aaaaaagaaa
     6241 tacagttcct cacatggaag atggggataa agagatactt aaaaaagcta aaatggattt
     6301 tatagctgta aattattata ggacaaattg tgcagaagct ttacctgaag attcacaaca
     6361 tccatttgga ttaagagaag gaactgttga ttttagtatg tatggactat ttaaaatgtc
     6421 aatgaatcct aacttagagg cttctgagta tggagcagca atagacccat caggtcttag
     6481 agttgcctta aatgaatatt ggcaaagata tcacttacct gttataataa cagaaaatgg
     6541 tctaggagct aaagatatat tagaagatgg aaaaattcat gatgactatc gtatagacta
     6601 tttaagaagt catataaatg catgtaaact agctattgaa gatggtgtag agatgattgg
     6661 atattgtcca tggtcattta cagacctttt aagttcttct caaggtttta ataagcgtta
     6721 tggacttgtt tatataaata gaactgacca tgaagtttta gatttaaaaa gaatcaagaa
     6781 agatagtttt tactggtata aagaagttat agagaacaat ggaatagtaa aataaacata
     6841 aatatatatt gagggtttta gtatgtacat tacaaaggta ttaaataatt cgttgctact
     6901 tgcaaaggat gataatgatg aagaaataat attgatgggg aaaggcattg gccataatta
     6961 taaggccggg tctgagttaa ataaaaaaga tatagaaaag atttttgttc ttcatgatga
     7021 aaatataaaa aagagtatta tacaattggc aacagaaata gatgcagaat attttggtat
     7081 agctcaaatg ataattgcat atggaataga aaaatataac ttaaaactta tgaaccatat
     7141 atatttggcc ttaactgacc acattgcctt tgcagtgaga cgctttaaag aaggtataat
     7201 gattgaaaat cactatttgt tcgaaatcaa ggaatttaat ccaaaagagt atgatatagg
     7261 aaaatatgct attactgttt ttaaggaggt tcttggttta gacctaccag aagaagagat
     7321 tggtaatata gcaggccatt ttataaatgc acaacaagat aatccttata gtgatagaaa
     7381 taagagaagt gctaaaattg taaatgctat tttgcaaata gttcattatc acttttctat
     7441 tgtatataat aaagagtcat tttattatag gagatttgta atgcatctaa aggccttttc
     7501 acaaagattt ctggctaatg aaccatcaag agaaaaaata gattttatat atgagcaagt
     7561 tcaaaaaaat tgtaaggaag agtatgaatg tgtgaaaaag gtaggagctt atatgtataa
     7621 ggaatactcc agagaattac caagacaaga ggagttatat ttgatgattc atattcataa
     7681 gattttagga gaattatgcg aaaatagtta gaatatctta atatgctagt aatattataa
     7741 aaaattaaaa attaactaca ctttaaatat gaacaattgc attacttaag ggggttgtct
     7801 taaaattgat ttttttaatt aaatttgaag ctcaactcct tttttaaacc tttatatcat
     7861 tacaacttta atgtttatac gcctgtactt tagatgtata tctacttttt acatttctca
     7921 acatgcaaac ctaccatttt ttgcagtatg ttaattgaaa taaaccattg agttaaccct
     7981 aaatttattc tggacttata ggaatagttc caaagatact ttaaaatatt ttctggaata
     8041 attgcttatt tcacatatgt tttattgtga tgttttgatt taataaattc ttcaactctg
     8101 tatatagtaa atgtattatc atgtttgttt tattcaagca cacttataat acgcttgatt
     8161 ttttcacaat gatgaaatat actaatgggt gttataggta taagaatcga attacacttg
     8221 aagaagtaag tgataaatga gatataaatc ctcatatgat aaactactat ttcattgagg
     8281 aacatattct aagtgatgtc aagatactac aatatgacta aattcctagt gataaaaaag
     8341 tctacgaatg agtgtagaaa ggggaactaa gatgaataaa gttttaatta tagatgatga
     8401 taaagatctt tgtattttgt taaaaaagag tatttcaatt gaacagattg aagcaaacta
     8461 ttgccattct gggagagatg gactggttga actttcaaaa caagattatc agttagtagt
     8521 tctagacgtg atgatgccag gtatggatgg ttttgaaact atggaacaaa tacgaaaata
     8581 tagcagtatt cccatcttaa tgctgacatc aaaaagcgat aattacagca aagtgcatgg
     8641 attgcgagct ggtgcagatg actatctaac caaaccattt gaaattacag aatttactgc
     8701 tcgtgtactg tctttaatcc gacgttacac ccgttttaat ccaaaaaatg aggaaccaca
     8761 gcaactttct ttcaaaggtt tgttgattga ccttgaccag catacagtga ctaccaatgg
     8821 cgaacctatg ttgcttccac ccaaggaatt tggtgtgctt ctttactgtg caaggcatca
     8881 gggtaagatt ttgacaaaac agcagattta tgaagctgtg tggggtgagc catatgtata
     8941 tgatgacagc aatatcatgg ctattatcag tcgcctaaga aaaaaaattg aactagaccc
     9001 atcatctccc atctatttgc aaacaataaa aggaattggg tatcaattca acacggaggt
     9061 atgaaaatgg atgaacaaac gataattctt ttcttattct tgctgtcgat tggtctactt
     9121 tttctttcca tatttgcttt ttccaagctt gggcatattc acaaacgcct aaaagatata
     9181 gaggagatac tggctgatgt acaaattgga aacgaaaatc gcaaaatact aattaagcca
     9241 tgtgatgtta tggctccatt ggtttatcag cttaatgaga ttgtctacga ttatgaaaat
     9301 aagttacttt ctctgaaaaa gtcggataaa gctagcaaac aacttatgac aagtctatct
     9361 catgatgttc gtacaccatt aacaactctg attggttatc tggatgctgt acacagtggt
     9421 atagttatcg gacaagaacg ggaggaatac cttgaaatcg ctaggcgtag agcctacgac
     9481 ctcaaggatt acattgatgt tctttttgac tggtttcggt tgaactctga tgaatttacg
     9541 ctgtcaatag aatctgtgga aattgcagag ttgtcacgca atattttgaa agactggatt
     9601 cctatattcc atgaaaagaa actgaatttt gaaattgata ttccagaaaa tcgactaatg
     9661 gtaaatctcg acccagatgg atattcccgt gtggttaata atctggttca aaatgttctt
     9721 gctcacagta aggctcggca aatcaagatt accatgagtg aggattccag aatggtatta
     9781 ctccgtgttg atgatgatgg tgttgggatt gccagagaaa atttaccaca tatttttgag
     9841 cgactgtata agtgtgataa aggacgttca gaaaaaggaa gtggtcttgg tctatctatt
     9901 gtcagtcaaa tggtggagcg aatgggtggt cagatttccg tagaaagtga gattggaaag
     9961 tataccgtat ttacagtgag cttaccatta atataaaatt gtttttcccc catgtgacat
    10021 gtatacacag ggggattttt tgtaagttat aaagttgcaa ggttaataca aggttgttgc
    10081 aaggttaatg taagattgag gtggtatgat agctttaata aacaaaggag gattttatta
    10141 tttatgaata atttaattat tgaaacaaaa aatctcacta agcaatatgg tgctcaaaag
    10201 agcgtttcta atttgaatat tcacgttcag aaaggtcgca tttacggatt gctaggaaga
    10261 aacggtgcgg gtaagacgac aactatgaaa atgttattgg gtctaacaaa accaactact
    10321 ggagaaatta aaatatttgg tcaggacatt cacaataacg agaagaagct tcttcctcga
    10381 attggatgtt tgattgaatc accagggttt tatcctaatc tgacaggaac agaaaatctc
    10441 aaaatctttg caaggcttag aggaatacca aaaaaaaatg cagtagaatc agcactggat
    10501 gtagtcggtt tgccaaacaa tgacaaaaag ttattttctc aatactctct tggtatgaaa
    10561 cagaggttgg cgattgctct tgccattatg catgacccac aactgttgat tttggacgag
    10621 cctatcaatg gacttgatcc tattggtatt gcagaagtaa gaaagtttat tcgtgatctc
    10681 tgcacagaac gaggtaaaac tattttgatt tccagtcaca ttctttctga aattgccttg
    10741 ttggcagatg acattggtat tattgaccat ggtattttgt tggaggaaga aagtcttgcc
    10801 caattagaag aaaaaaacag taaatacata cattttgctg tatctgatgc agcacatgca
    10861 gcaaggcttc tggaaaccca acttaacctg aaaaatttca aagtagcaga taattacaat
    10921 attatgctat atgatacaga tgtttctgtt gcagaaataa atcgtgcttt cattctaaac
    10981 aacattgagg tatcagaatc tcatttatgc gaagatactc ttgaagatta cttcaagaaa
    11041 gtaacagggg gtgaaggaat tgcttgatat aatttcatgt gaattttcaa aactcaagcg
    11101 gttaaaattt atactgattt ctattttagg tgcttgctta tttccaattc ccgcaacaat
    11161 tttgattgca aaggacaact tgccctttga gcaattgttc aaattagttg tcaattttgg
    11221 atattttttg ctattaccaa ttgtattaag tattgttgct agccaactat tttttataga
    11281 aagagataac gatgtattaa aaaatcttgc aacagtgcca gtgccaaaag gaaaactggc
    11341 tctggcaaaa ttggctgtgt tgctgtttat atcattgttc tactccgttg cagggttagg
    11401 agctactatc attggaggtt tcattgttgg aatagtagag ggggttactg taaaattagg
    11461 aatgagcatt gcttttggaa ttatgttttt tgttactgta cttcctgttg tggtactcat
    11521 tgtatatttc aatcgcagct atattttttc tattatactt tcttttgtat atgctatttt
    11581 caattttagt atatccttaa atattatcaa ttttgaacca aataacccac tattaagcgt
    11641 attacctgct cctgttataa tgcgttggtg gatggcattt tggggagatc ccactggcga
    11701 atacacggca cttagacagc catatttgct ctcaactcct gcttgtgtag gtattttatg
    11761 tttgataacc attatagcag tcctgctgat ttgtatgata tacaaaaagc aggagaatta
    11821 ggaggtatct atgcttgata taattactac agaatttcaa aaaataaaaa gatataatat
    11881 tctatggatt ggtgttgttg ctgttctgtt ttcagcacta ttggcagttt ttcaggttgt
    11941 aagttcacac ggcagtgacc ctctaacgta tgagagcttt gcaaacggag ttatctggaa
    12001 taatttcagt cttagttttc catttgggat tacacttatt ggaggatatc ttattaaccg
    12061 tgaatataca gaccaaacct taaaaaacat cctaactgtt cctatttcat tacgcaaatt
    12121 gctagtggga aaattaattg cggttggagg aattgctgta ttgttaagtc ttttcagctt
    12181 cttatgcaca tttattttgg ggttgttatt ttgcaatatc aatatatctg ttacactcat
    12241 tgtaaaatcc ttagttcaga ttttgtctgt taatctgtat tgttatgttg ctgttttgcc
    12301 gattattgct tattttggtc gtaaacaaaa tgcatttctg acgggtgtag ggattgcatt
    12361 tgtatacggt ttttgtggtg tgtttgttgc tggaagaaat ctgacagact tttatccaat
    12421 cacagcaggt cttggtctag ttggatacaa caatggtgct ggtactgttt atcagccact
    12481 tatcggtgct atgactttga ttgtaattct aatcttgaca actattctac ttgtatttac
    12541 acctaattat gataaagtta tgaccatatc taagaaaaaa gggataaagc ataaaaagta
    12601 ttctcataaa taacataaat attgtttcta ttatttaagt tgctagacag tgaaaagaaa
    12661 aaatctgtcg tacagtggct atatgctcat gtattcaaga agctacagtt ttgatttttc
    12721 ataactgtag cttctttttg tatttattaa atcacggcta tcataatact tgcaataggt
    12781 atagcgacaa gagagagtac tgtcatgtgt gttttatata ttacattaag tatattctaa
    12841 aatatatgtt ttaaataata tatttgaaaa taggaatatt taaataaaaa aaataatatt
    12901 atatatagtt gacaaaaatt ggcaaatgat ataatatata aatatagaaa tagtaatcat
    12961 tactattatt aaaaagggag gaattaatta tgaacttaaa aggaactaaa acagaaaaga
    13021 atttaatggc aggatttgca ggagagtcag aagcaagaaa taaatataca tactacgctt
    13081 caaaagcaag aaaagaaggt tataatcaaa tagctgctat atttgaagaa actgctaaca
    13141 atgaaaagga acatgctaaa ttatggttta aacttttaca tgatggtatg ccttcaacag
    13201 aggaaaattt aaaggatgca gcagcaggtg aaaactatga atggactgat atgtatgcaa
    13261 aatttgctaa agaagctaga gaagaaggat ttgacaagat agcttattta tttgaagctg
    13321 ttggaaaaat agagaaagag catgaagaaa gatacttaaa gcttttagaa aacttaaatg
    13381 aaggaaaaat atttaaaaga gatgaagaag ttgtttggca atgtcaaaac tgtggtcatg
    13441 tgtatgtagg tactgaagca ccagaaaaat gcccagtatg tgaccatcca aaagcgtatt
    13501 tcaatataaa agctgaaaat tattaaaaat tatcattatt aaaaaggaat gttaactatg
    13561 aaattttcta aacaacgaga actgatttta aatgaaatat taaataatcc ggttcatcct
    13621 actgcggatt acctatatga aaacttaaaa aaagataatc caaatttaag cttaggaact
    13681 gtttatagaa atttagctca gctaacggaa catggcttta taagaaaggt tagtattcca
    13741 gggtatccag atagatttga tggtcgaata gataatcact atcatatcat atgtgaagta
    13801 tgtggagagg tatacgattt agaatccgaa gttcttaata atttacaaga attaatatct
    13861 gaggagacag acataaaaat aacatcttat aacataagtt ttaaagggat ttgtaataat
    13921 tgtaaaaggt gtagccaagt aggttagttt tcaaattcta aaaataatta atgaggtgag
    13981 tttatgtgta gtgaacaaaa attttttata tgtgagactt gtggaaacct tgtaggaatg
    14041 atacaaagtg gtggtgtacc tattttctgt tgtggaaaac ctatgaagga acttgttcct
    14101 aatacaacag atgcagcagt tgaaaaacat gtacctgtaa ttgaagtgga tggaaataat
    14161 gttactgtta aagtaagtag cacaactcat ccaatgacta aagaacatca tatagcatgg
    14221 gtgtatctta tgactgaaca aggtggtcaa cgcaaatgtc tagcagtaga tggagaacct
    14281 gtagttaaat ttgctttgaa tgatgatgat aaagtgattt ctgcctatgc ttactgtaat
    14341 ttacatggat tatggaaggc tgaactgtaa tatttaaata aattgagtca aagaggaggc
    14401 tataaatgta ttttcataca aatagcctcc tataaattta tataaattca agttttaatt
    14461 ttgtttaatg tcaatataat ataaggagaa aataatatgt caatttataa atgtagtgtt
    14521 tgtggatata tttatgatga atctaagaat gataaaacat gggatgaatt aagtgaagat
    14581 tgggaatgcc ctgtatgtac aaaaggtcgt agttattttg gaaagataag cactgtttac
    14641 tatgaagaag atgaaaagat agcagaagac atagttgaaa atgaatctaa attaaatact
    14701 gaaaaagagg gagatttaaa ttacttaagt acatatttaa gaagagatga tgaagttgag
    14761 aaacatatgg atataattca cgaaatggct gttacaggaa aatctataat agaacctatg
    14821 agaactaaac taccagtaat ttcttgggat gatattttaa ttatgggtgc tcaattaaat
    14881 ccattacctt taaatgagca tgatgaagta aatacaacaa caataatagg aaaaaaagca
    14941 aagaaaccta tgattataga aaatccagtt tatatttccc acatgtcatt tggagctttg
    15001 tctaaagaac taaaaatagc tttagcaaag ggtgcagccc aaaataagac agctatgtgt
    15061 agtggtgaag gaggtatatt accagaagag aaggaagctt catacaagta tatttttgag
    15121 tatgtaccaa ataaatatag tgtaactgaa gaaaatctta aaaattctga tgctatagag
    15181 ataaaaattg gtcaaggaac aaaacctggt atgggaggtc atcttcctgg cgaaaaagta
    15241 actgaagaaa tagcaaaagt aagaaataag cctgtaggtc aagatgtaat aagtccatct
    15301 tgttttgagg aaatacaatc caaagaggat ttaaagaaac ttatagatga acttagagaa
    15361 gtttcagaag ggcgtccaat aggtgttaaa atttcagcag gtcatattga aaaagatatg
    15421 gaatttatag cttatgctaa acctgatttt gtaactattg atggtcgtgg tggagctact
    15481 ggagcaagtc caaagttgct taaagatgca acttcaattc caacaatatt tgctctttat
    15541 cgtgctagaa aatacataga tacacatgga ttagatatag atttggttat aacaggtggg
    15601 cttcgtatat ctactgattt tgctaaggca attgctatgg gggctgatgc agttgctatt
    15661 gcaagttctg ctcttatggc agcggcgtgt caacaatatc gtatatgtgg ttctggtaag
    15721 tgtcctgtag gagtagctac tcaggatgag gaattgagaa aaagattaca tatagaaaat
    15781 agtgctaata gagtggcaaa ctttttaaat gtaagtttag aagaacttaa gacttttgct
    15841 agaatttctg gtcataaaga tatacatgat ttaagtgttg atgatttata tactgttaac
    15901 tctgaaatat caaattatac aaacatacag catgtataga ttgaagtttg aaactattag
    15961 attttagata gctataaaag taaatgataa atatatttta taaaagagag tgtcttaaaa
    16021 tgaacttttt agttcataag tcactctttt ttgtatgaag ccaaatatat ttatcatttt
    16081 agcaatgaaa aagaatctta tctctttatt ttgagataga ctccttctat ttatgaaaat
    16141 taaagatatt aaattgtaaa atattctgtg atgtcgtact attaaactaa agattctgta
    16201 ctttaaagta aataaaaatt taaggagtgc ttattatgga aagattgaag atacaagttt
    16261 tagttgacaa taatacttat attgatagat actttgttgg agaaccagca gtaagctatt
    16321 atattgagat tgatggaaat aggattttgt ttgattcggg atattcagat gtattcatat
    16381 caaacgctga aaaattaaat atagatttag gaaatttaac tcatgttgtt ttttctcatg
    16441 gacataatga ccatacaaga ggtatccagt ttttagaaaa taggtatgat ttatctacag
    16501 ttgaacttat ttcacatcct aactgtttta tacctagaaa acatggagag aaaagcatag
    16561 gagctccatt ttctgctgag gaaattaaaa atatttttat gtataatcct aaggataagc
    16621 catttaatct aagtaagaat tgtgtgtttt taggtgaaat accttctata aataattttg
    16681 aaaaaagagc taaaattggt aaatgtaaaa taggagattt gtgggaagat gattatgttt
    16741 tagatgattc tgctatagtt tgtaaaactg ataaaggtat ttttattgtt acaggatgtt
    16801 ctcatagtgg aatttgtaat atagtagagt atgctaaaag ggtatgtgga gatgatagag
    16861 ttattggtat actaggtggt tttcatcttt ttgaattgaa taataggtta gatagtacaa
    16921 tacaatattt ggataaagaa gaaataagaa tgttgtaccc ttgtcactgt gtttctttta
    16981 aggtaaaagc taagatgaat gaaatattga atataaatga agttggagta gggctgacca
    17041 taagtatata gtatttgaaa gtatataaga tttaagttga aggttaaaaa gatattttct
    17101 atagaaagta tcttttttgt tacgtttatt ttaagagaaa tcaatatact tttatatgaa
    17161 atattgtaaa aaaatttatt tttaatgaga atatattttc attaataaac aattttatta
    17221 tgtattaata atgctagaat aaatataaat aaatcaaagt tacttacatt aaagtatatt
    17281 ttttcacaaa atatattgat ttattctttt aaagtttgat aattccaatg aatgtaataa
    17341 aagaaggg
//
LOCUS       DACTZW010000087        16804 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.087, whole genome shotgun sequence.
ACCESSION   DACTZW010000087 DACTZW010000000
VERSION     DACTZW010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16804
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.087"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(78..1076)
                     /locus_tag="JAM15_15400"
     CDS             complement(78..1076)
                     /locus_tag="JAM15_15400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhdH/YhfP family quinone oxidoreductase"
                     /protein_id="HAT6799636.1"
                     /translation="MNKKFKSLYITEEEGNFRRNIVERELDTLPEGEVLIKVKYSSLN
                     YKDALSANGNKGVTRKYPHTPGIDASGIVESSSCDDFKIGEEVLVTGYDLGMNTSGGF
                     SEYIRVPSSWVVKLPKNLSLKEAMDYGTAGFTAALSVYKFIDSVDKNMGDVLVTGGTG
                     GVAVIATKILIKLGYSVVVSTGKLEEQKEVLLNLGVKDVIHRSEVDDNSGRPLLRPRW
                     AGVIDTVGGNTLATAIKTTNYCGAVTTCGNAGGVDFTSSVYPFILKGITLYGIDSVDC
                     PMNLRLKIWDLLSNEWKLDDLDDMVNVVSLEELNDSIDSIMTGKHVGRTVVDLEKI"
     gene            1180..1617
                     /locus_tag="JAM15_15405"
     CDS             1180..1617
                     /locus_tag="JAM15_15405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAT6799637.1"
                     /translation="MEDKYIVHFISKTKANMIKFIENKLSKNGLGELIPTHGNILTAL
                     YENNGILTMKEIAVKIGKDKSTVTVLVNKLINLGYLERQKCTNDKRITYIKLTKKALL
                     IEDTFNSISTQVKETAYHNITENEKQEFLRILKKINDNFKNAD"
     gene            1703..2290
                     /locus_tag="JAM15_15410"
     CDS             1703..2290
                     /locus_tag="JAM15_15410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HAT6799638.1"
                     /translation="MNLKDSKTKENLLRAFAGESQARNRYNISASVAKKEGLYTIESL
                     FNYTADQEKSHAKQFFSKLKEFAGENISISGAYPVDLYDKTAQHLKAAQHNELQEWDD
                     VYKNFGKTAREEGFESIAKLFENIAEIEKVHGDRFGRYATDLEEGTLFRRNEDIQWIC
                     THCGHIHVGKEAPKACPVCLHPQGYFLDFKNSLFE"
     gene            complement(2590..3210)
                     /locus_tag="JAM15_15415"
     CDS             complement(2590..3210)
                     /locus_tag="JAM15_15415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbD family protein"
                     /protein_id="HAT6799639.1"
                     /translation="MEELISKKDLLSKTNISYGQLYRWKRKNIIPEEWFIKKSAFTGQ
                     ETFFPRDKILERIELILSMKEETSLDDIANMFMKKDINKEFDIDFILSKEVICNYTKE
                     IFQNLYKKEQSIGKKELLILSIIEKFLVKSIITFEELKLIVNIIEENFVSIYNENGKI
                     YLFRKFGVPFVVGCLDYKKVKFEKDVVKIIEIDLTKEINDISIKLS"
     gene            complement(3218..3985)
                     /locus_tag="JAM15_15420"
     CDS             complement(3218..3985)
                     /locus_tag="JAM15_15420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymer-forming cytoskeletal protein"
                     /protein_id="HAT6799640.1"
                     /translation="MENGSIKILGEGFISSGEYESIKIVGSSKSKGNVKSNEVKVLGD
                     SKFEGDINIKNFVVNGKTIIRGNLKAERVRVNGQLNIEGDAEIDDLVITAQQKVDGKL
                     KCNNVTIRGQLSVNENMYAQDIKIYGEMRNKSNIECEDIKVYGVIKCDGLLNGENIYI
                     YSGGGSYCKEIGATNIKIGRSKDAFSLIKIINIFSGKFKCNLIEGDTIELEDASIKDI
                     RGKSISLVDNCDVGNIEYSDNLSVSDNSTVKNSIKVG"
     gene            complement(4026..4847)
                     /locus_tag="JAM15_15425"
     CDS             complement(4026..4847)
                     /locus_tag="JAM15_15425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799641.1"
                     /translation="MNEELSSLRFDGVGKCKGGIFDNVNISGTGKIEGSVKCSKFDSS
                     GSAKVFGTTECNEFFTSGLSKVEGNILASKVEISGLLRCTGNINSVEIDTNGIINVEG
                     SIKSDIIHGEGYLKANENIDCENVNLSGILECNGFLNCEEVNINLNGISNFNEVGASS
                     VNIKKGHGDYCKKFRMLEKKHINFEKVSSNLISLGLLSIRKYTESKLFANIIEADEIS
                     LENSEVKVVRGKNIKIGKGCYVESLEYSESIEIDEDSIVGEIKNISEKVKLEKDK"
     gene            complement(5204..7114)
                     /gene="phnW"
                     /locus_tag="JAM15_15430"
     CDS             complement(5204..7114)
                     /gene="phnW"
                     /locus_tag="JAM15_15430"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HAT6799642.1"
                     /translation="MKKIYGEKIKAVVFDWAGTTVDYGCFAPLNVFIEIFKRRGIDVT
                     MEEARKPMGKLKIDHIREMCEMDRIKNIWSDKFGKVPTEDDVNELYAEFEPMLFETLE
                     EYTTPIPHVVETIEKLRKNGLKIGSTTGYTREMMNIVEPSAAKKGYSPDFLVTPSEVS
                     QGRPYPWMCYKNAEALGVSPMSSMVKVGDTISDVKEGVNAGMWSVAVIKGSSELGLTQ
                     EEVENMDKEELKAKMSIVSKKFKEAGAHFVIETMAELEDILIKIENETIKSDFVPEND
                     YILLTPGPLSTTKSVRASMLKDWCTWDVEYNNLVQDVRRRLVSLATQNTDKYTSVLMQ
                     GSGTFSVEAIIGSTISKDGKLLVIANGAYGKRIKDICNYLNIEFVDCTFKDIEAVDLN
                     VVENLLKENKDITHISMVHCETTTGRLNPIQEVGKLAKEYNKIYIVDAMSSFGGIEID
                     VEDFNIDFLVSSSNKCIQGVPGFGFIIANKEELSKCKGIAKSLSLDVYAQWETMEKNN
                     GKWRFTSPTHVVRAFYQALLELEEEGSVEKRYARYKENQFTIASRLKSLGFDTLVNDN
                     AQSPVITTFLYPKNAKFEFMEFYTYLKENGFVIYPGKLTDIDTFRIGSIGEVYPTDME
                     RLADVIEKFINR"
     gene            complement(7393..8178)
                     /locus_tag="JAM15_15435"
     CDS             complement(7393..8178)
                     /locus_tag="JAM15_15435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAT6799643.1"
                     /translation="MSLNSIDRKKEILKLLDSKGKVNTKELVKRLEVSSETIRRYLEE
                     LENENKLKKVYGGAIKINYGVIEPEHIKRNNTNLDKKQSIAKYAAKFVNDNESIIIDE
                     GTTNLQIVDYIISVNNLKIITNSYPVLSKLISYENQGLFDGEVIFIGGKVNLKHQRTA
                     CPMSIDTMKNLYVDKAFISSEGILDSFGISSIDQNKALLSKEYIKNSKESFVLCDSSK
                     IGIASMYKIADLEELDFVICDVEPPNEWKDKLNEINITWIEAK"
     gene            complement(8395..8625)
                     /gene="dltC"
                     /locus_tag="JAM15_15440"
     CDS             complement(8395..8625)
                     /gene="dltC"
                     /locus_tag="JAM15_15440"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008428447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HAT6799644.1"
                     /translation="MQETVIEIFEDVLGTDEIREDLDLNLFETELLDSLAIIEVLLEI
                     ENRLGIELQPTDLERKDMSTVNNLVKFLETRK"
     gene            complement(8644..9792)
                     /gene="dltB"
                     /locus_tag="JAM15_15445"
     CDS             complement(8644..9792)
                     /gene="dltB"
                     /locus_tag="JAM15_15445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HAT6799645.1"
                     /translation="MIFSQYGDYFYLYILLLTSIPAVILGLMGKNIKYYGMLASLFML
                     FLIVGIDVQLKYLVIFIILEVIIVKGYEYVRRKTKNKYIYWGFLFASMLPIIINKISP
                     VTSFGIIGFIGISYLNFRTIQMVIEIYDGAIKEVKISKMLYFMLFFPTLSSGPIDRSR
                     RFEQDLEKHISRKEYIEEYLLPGIKNIVMGVGYKFVIAFLINTYWVSRIPKDMSFINI
                     LSYMYAYSLYLFFDFAGYSLFAIGTGYIFGIQVPINFDKPFISKDMKEFWTRWHISLS
                     RWFGDYIFSRFVMSSMRKKRFKKRTTAAHVAQMITMITMGFWHGLTWYYVAYGVYQGL
                     ALVLTDIYQRKSKFYKKHKKDKWFERVQIFITFHIVCFGLLIFSGYLA"
     gene            complement(9792..11306)
                     /locus_tag="JAM15_15450"
     CDS             complement(9792..11306)
                     /locus_tag="JAM15_15450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase"
                     /protein_id="HAT6799646.1"
                     /translation="MKIIEGIKKYSNTDRTALMCNGDKLSYKDLNEYSDAISVFLKDV
                     YKEEDTPIVIYGNKENMIMACMIGALKSGRAYVPLDISFPIDRVFEVTKEIKPKVIFN
                     FSDERNFGDINVIDMDKLNDIINEYQGKSLDKENWVKDDENAYILFTSGSTGKPKGVQ
                     ISSNNLDSFSDWISPYLNIDGSEKVIMNQPAYSFDLSVTTIYPGLIHGATLFSISKDV
                     LADYKELFRQFSISDIAVWVSTPSFAGVCITEKEFNSKMLPNLESMIFIGEALSKNLT
                     KELMSRFSNTRIINGYGPTEATVGVSVNDMTQKAIDDEKSLPVGYPMSNCKIKILDED
                     GNELKENEKGEIIIIGPSVSKGYFNNKEKTDEVFFYDEIDGVKWRAYKTGDMGYLLDG
                     NIYYCGRKDFQIKLNGFRIEIEDIENNLRKVHNVKNAVVLPVYKDEKIAYLKGIVELN
                     EKNDLSNIKNGMIIKKELGKYIPSYMIPRNISIISEFPTNINGKIDRKKLMEEI"
     gene            complement(11427..12617)
                     /gene="dltD"
                     /locus_tag="JAM15_15455"
     CDS             complement(11427..12617)
                     /gene="dltD"
                     /locus_tag="JAM15_15455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HAT6799647.1"
                     /translation="MRKLIYFITPFIIGVVFLFGLDKFLDSKTDELLREKNLLPIMDD
                     TLSDIKDKGVTANNHFLREKDIMILGSSELSNSTKQHPKYYFNTNRSKNKVFAIGRAY
                     TQTLQDAAILGSMNPNIDNKKVVLLISMQWFMEKDGVTSHHYQSRFSPIQFYRFLDNP
                     KISKQNKIEYAKKSSKLLWGSDEYKAEALYAKLYEPKTFPEKAEKVLLEPYFQGRKYC
                     IALKEKGILYKRLIKLDKKRATKRKRPINWSYERKKAIEDAKKRVGKNPLNIDKYYYK
                     EHFKDGIEQYKGRDKDVNLLTSKEFENYKLMLNVCTDLGIKPVVVLIPSMDKFYNLTG
                     ISEKERNQYYDKAQKIAESKGFEVLNLKDKGSDKYYLRDVMHLGTKGWVDVCERLFKI
                     FKEQ"
     gene            complement(12905..13921)
                     /locus_tag="JAM15_15460"
     CDS             complement(12905..13921)
                     /locus_tag="JAM15_15460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAT6799648.1"
                     /translation="MGKIRFGIVGTSNIANIFLRAASRVKDFELVAVYSRNLEKAREF
                     GTLHGASIFFDDLEQMAKSKDIDAVYIASPNALHSKQAITCLKHKKHVLCEKSLASNL
                     KEVKSMIKTAKDNNVLLMEAMRITCVPNFKAVKENLYKIGKIRRFFGSYCQYSSRYDK
                     YKNGIIENAFKKELSNGALMDIGVYCIHPMVNLFGAPKTVKAVSHILQTGVDGEGSAV
                     FQYDDMDAIIQYSKVADSYIPSEIQGEEGSIIIEKLNLFEKAIIKYRDGREEDISIPK
                     EKAEEKPREIEGMYYELVEFISLINNNKIESNINSHENSIIVMEIMDEIRRQSSIVYP
                     ADSI"
     gene            complement(14100..14639)
                     /locus_tag="JAM15_15465"
     CDS             complement(14100..14639)
                     /locus_tag="JAM15_15465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease"
                     /protein_id="HAT6799649.1"
                     /translation="MDNVGSLLYFLFNFFLYGFIGWIIENLYSYYKQGHFQEDGFLNG
                     PFKPMYAIAMSIIIEVSRFIDPNNIFALLLLCLVVPTVVEYITGILMKVYFNKVYWDY
                     SDYKYNSRGIVCLKFSVYWTILTFIGVRYFQVYIVDSLYSLIIPYWPILVTILLVTLF
                     VDEILTIKFLRGNKDIVER"
     gene            complement(14740..15420)
                     /locus_tag="JAM15_15470"
     CDS             complement(14740..15420)
                     /locus_tag="JAM15_15470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAT6799650.1"
                     /translation="MQKVEGIIFDMDGVLFDSERISLEFWMETFEKYGYTMTKEIYTS
                     VMGRNRKGIIEGLTDIYDSSVPIIDLYDEKTKNMIEFMERKGAPIKLGVNELISFLKE
                     NGYKMAVATSTKRERAVKRLAKANLKDYFDAIVCGDDVVNSKPNPEIFLKAAKKINVN
                     PQNCIVIEDSPMGVEAAYNGGIRCINVPDLKEPDEQIKSQSHKILENLLEVREYLKSL
                     NSKECHNL"
     gene            complement(15449..16738)
                     /locus_tag="JAM15_15475"
     CDS             complement(15449..16738)
                     /locus_tag="JAM15_15475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HAT6799651.1"
                     /translation="MRELLKVTLIVMLVLINAFFVACEFAMVKLRSSRIDTMITEGNN
                     NAKRCKIIKDNLNSYLSACQLGITLCSLALGWMGESTVKELILPIVSVFNLSESIIYT
                     ISISISFLIITMMEVVIGELVPKALALYNTEKIMLSTSFLLVGFYKLTYPIIYFFNLS
                     TDLFLKPFGYSQADEVDEPHTGDEIRLLVEESYKSGLIDESEQRLVDNIFEFEEKKIR
                     KIMVPRTDMVCIYESDSEEKILAILKEEGVTRYPVCRKNKDDILGFVHIRDLYNQKIN
                     ENKIELEEILRDIIYISENLTIDKALERIRKEKLQLAIVVDEYGGTSGVVTIEDILEE
                     IVGEIQDEFDKEETHIKKIGAGSYLVDGTESINYINKYFGLDIEHDGFDSIGGWISYM
                     LGSNIKVNQSVTFENYNFTILELDKLRVVKLIIKSVI"
BASE COUNT         5525 a         2990 c         1629 g         6660 t
ORIGIN      
        1 aatgagatac tcataagtaa atttcaagta tctcattttt gcttaaaacc tataatccta
       61 attataaatt tattcgccta tattttttct aaatcaacta ctgttcttcc aacatgtttt
      121 cctgtcatta tcgaatctat actatcattt aactcttcca atgatactac atttaccata
      181 tcatctaaat catctaattt ccattcattt gataataaat cccatatttt taatcttaag
      241 ttcattgggc aatccacaga atctatacca tataaagtaa ttccctttaa tataaatgga
      301 tatactgaac ttgtaaaatc aactcctcct gcattaccac aagttgttac tgctccacaa
      361 taattagttg tctttattgc tgttgctaga gtatttcctc ctactgtatc tattactcca
      421 gcccatcttg gtctaagcag aggtcttcct gagttatcat ccacttctga cctatgtata
      481 acatctttaa cacctaagtt tagtaatact tctttttgtt cttctaattt tcctgttgaa
      541 actacaactg aataacctaa tttaatcaat attttagttg caattacagc aactcctcca
      601 gtaccaccag tgactaatac atctcccata ttcttatcta cagaatctat aaatttatac
      661 acagataaag ctgctgtaaa ccctgctgta ccataatcca ttgcttcttt tagtgaaaga
      721 tttttaggaa gtttaactac ccaactagaa ggaactctta tgtattctga aaaaccacca
      781 gaagtattca ttcccaagtc ataacctgtt actaaaactt cttctccaat tttaaaatca
      841 tcacaactac tagattctac tataccagat gcatcaattc ctggtgtatg aggatacttt
      901 ctcgtaacac ccttattacc atttgcagaa agtgcatcct tgtaatttag agaagaatat
      961 tttactttta ttaaaacttc gccttctggc aatgtatcca attctctttc aactatattt
     1021 cttctaaaat ttccttcttc ttctgtaata tatagtgatt taaatttttt attcataaat
     1081 ttcctcccaa tacatttagt tttatgttaa actaattata gtttataaat agttttatgt
     1141 caaactaatt taaatagatt aaagattgga gaataattta tggaagataa atatattgta
     1201 catttcataa gtaaaacaaa ggctaatatg attaaattca ttgaaaataa actcagtaaa
     1261 aatggtttag gtgagttaat acctactcat ggaaatattt taactgcact ttatgaaaat
     1321 aatggaatac ttacaatgaa agaaattgca gttaaaatag gaaaagataa atccactgtt
     1381 acagtgttgg ttaataaact tataaaccta ggatatttag aaagacaaaa atgtacaaat
     1441 gacaaacgta tcacgtatat aaagcttaca aaaaaggcac tgcttataga agatactttt
     1501 aatagcatct caacacaagt taaagagacg gcataccata atattacaga aaatgaaaaa
     1561 caagaatttc ttagaatttt aaaaaaaatt aatgataatt ttaaaaatgc tgactaaatt
     1621 gagcataatt atatctccta ttggaataat aaataaaaag aatcaaatat tgtaaaaatt
     1681 tattgtgata gagaggtaga atatgaattt aaaagatagt aaaactaaag aaaatttatt
     1741 aagagctttt gcaggtgaga gtcaagctag aaatagatac aatatttctg catctgtagc
     1801 aaaaaaagaa ggattatata caatagagtc tttatttaat tacactgctg accaagaaaa
     1861 atcacatgca aaacaattct tttctaaatt aaaagaattt gctggtgaaa atataagtat
     1921 atcaggagca taccctgtag atttatatga caagacagca caacacctta aagctgcaca
     1981 acataatgag cttcaagagt gggatgatgt atataaaaac tttggaaaaa cagcacgtga
     2041 agaaggattt gaatctatag ctaaactatt tgaaaatata gctgaaatag aaaaagttca
     2101 tggtgataga tttggtagat atgctactga tttagaagaa ggtactttat tcagaagaaa
     2161 tgaagatata caatggatat gtacacattg tgggcatata catgtaggta aagaagctcc
     2221 aaaagcttgt cctgtatgtc ttcatccaca aggatatttc ttagatttta aaaactcatt
     2281 atttgaataa actaaggtaa tcattgtatt taaacaattt actatattta tatcaagtat
     2341 ttttataaat actgtattat cttaataaca ataaaatgaa ccattgatat tactataagt
     2401 agaaaatgta gtttaaatac aatttatagt agttcatcat ggttcatttt attgtttact
     2461 aatccctata acttacttaa atctatcttt aacttttaca tactcacata aaacctcatc
     2521 tttaaactaa atatttaaat aaagtgtatt ttaagtagat tattataata cattatataa
     2581 gataatacac tatgataact ttatacttat atcatttatt tcttttgtca agtcaatctc
     2641 aataatctta actacatctt tttcaaactt tactttttta taatccagac atcctactac
     2701 gaatggaact ccaaactttc taaacaaata aatctttcca ttttcattgt atattgatac
     2761 aaaattttct tctattatat tcactatcaa ttttaactct tcaaaagtta ttatagattt
     2821 aactaaaaac ttctctatta tgctcaatat aagcagttct tttttaccta tgctttgctc
     2881 ttttttatat aaattttgaa atatttcttt ggtataatta catataactt ctttactgag
     2941 aataaaatca atgtcaaact ccttattaat atcctttttc ataaacatat ttgcaatatc
     3001 atcaagagaa gtctcttctt tcatagacaa tattaactct attctttcta gtattttatc
     3061 tcttggaaag aaagtctctt gacctgtaaa agctgatttt tttataaacc attcctctgg
     3121 tattatgttt tttcttttcc atctatataa ttgaccataa gatatattag ttttgctcaa
     3181 taaatctttc ttagatatta attcttccat aacttttcta gcccaccttt atactgtttt
     3241 ttacagtaga attatctgaa actgataaat tatcactgta ttcaatattt ccaacgtcac
     3301 aattatctac tagagatatg cttttacctc gtatatcttt tattgatgca tcttctaatt
     3361 caatagtatc tccctctatc aaattacatt taaactttcc tgaaaaaata ttaatgattt
     3421 taattaatga aaaagcatct ttgcttcttc ctatttttat attagttgcc cctatctctt
     3481 tacaataaga acctcctcct gaataaatat atatattttc tccatttaaa agaccatcac
     3541 attttattac tccatatacc tttatatctt cacattctat atttgattta tttctcattt
     3601 cgccatagat ttttatatct tgtgcataca tattttcatt tacacttaat tgtcctctta
     3661 ttgtaacatt attacattta agtttgccat ccactttctg ttgagcagtt ataactaagt
     3721 catctatttc tgcatctccc tctatattaa gttgaccatt cactcttaca cgctctgctt
     3781 taagattgcc tcttataata gtttttccgt taacaacaaa attttttata ttgatgtcac
     3841 cttcaaattt tgaatctcca aggactttta cttcgttact tttaacattt ccttttgatt
     3901 tagaacttcc cacgattttt atactttcat actcaccact acttataaag ccttctccaa
     3961 gtatttttat agacccgttt tccatattat tacctcattt taaattttat ttttaaacct
     4021 acttattact tatccttctc taattttact ttttcactta tattctttat ttcaccaact
     4081 attgaatctt catcaatctc tatactttca ctgtactcca aactttctac ataacatccc
     4141 ttgcctattt taatattttt tcctcttaca actttgactt cactattttc taagcttatt
     4201 tcatctgctt ctataatatt tgcaaacaat ttactttctg tatactttct aattgataat
     4261 agacctaaac ttattaaatt tgaagacact ttttcaaagt tgatatgctt tttttctagc
     4321 atacgaaatt ttttgcaata atctccatgc ccctttttta tatttacact acttgctcca
     4381 acttcattaa aattagaaat tccatttaaa ttaatattaa cttcttcaca attcaaaaat
     4441 ccattacact ccaagattcc acttaaattg acattttcac aatctatatt ctcatttgct
     4501 tttaaatatc cttctccatg aataatatcc gattttatac ttccttctac attaataatt
     4561 ccattagtat caatttcaac agaattaata tttcctgtac atctaagaag tcccgatatc
     4621 tcaacttttg atgccagtat gtttccttct actttactta aaccagatgt aaaaaattca
     4681 ttacattctg ttgtcccaaa aacttttgct gaaccagaag aatcaaattt actacatttt
     4741 acacttcctt ctattttgcc tgttcctgat atattaacat tgtcaaaaat tccaccttta
     4801 cattttccaa caccatcaaa tcttagtgaa cttaattctt cattcataat gatatccttt
     4861 ctttaccgta ttttatcttt aaactcaata taacaaaaca ttgttacgtt gtcaagtgtg
     4921 ataataatac ttaataaagc aactatcatt tattttctat aaataggcat aaaaataata
     4981 gggaaatgct ttatttaaac tataaatcta atttcttaga ttttgattta aataaaatat
     5041 atccctatta ctcaatcttt atatattcat tgtataaact tctaaaatat aagtctttaa
     5101 attctactgt caatactttt tatacactgt ttgtgctatc atctcacacc taaaggagtg
     5161 ggctttccgc actattctgt aacctacaag acactatctt cttctatctg ttaataaatt
     5221 tttctattac atcagctaat ctctccatat cagttggata aacttcacct atgctaccta
     5281 ttctaaatgt atctatatca gtcaatttac ctggatagat aacaaatcca ttctctttta
     5341 aataagtata aaattccata aattcaaact ttgcattttt aggatataag aaagttgtta
     5401 ttacaggtga ttgagcatta tcattcacca aagtatcaaa gcctaaagat tttaatcttg
     5461 aagctattgt aaactgattt tctttatatc tagcatatct tttttcaaca gaaccttctt
     5521 cttccaattc taataaagct tgataaaaag ctcttacaac atgtgtaggt gaagtaaatc
     5581 tccatttacc attatttttc tccatagtct cccattgcgc atacacatca agagataatg
     5641 atttagctat acctttacat ttagataatt cctctttatt agctattata aaaccaaatc
     5701 caggtactcc ttgtatacat ttgttagaac tactaactaa aaaatctata ttaaaatctt
     5761 caacatcaat ctcaattccc ccaaaactac tcatagcatc aactatataa attttgttat
     5821 attcttttgc aagtttccct acctcttgta taggatttaa tctacctgta gtagtttcac
     5881 agtgaaccat tgatatatgt gttatatcct tgttttcttt taataaattt tctactacat
     5941 ttaaatccac tgcttctata tctttaaatg tgcagtcaac aaattctatg ttaagataat
     6001 tacatatatc ttttattctc tttccgtatg ctccatttgc aattacaaga agtttaccat
     6061 cttttgaaat agtacttcct attatagctt ctactgaaaa agtcccactt ccttgcatta
     6121 atacacttgt gtatttatct gtattttggg ttgctagaga tactaatctt cttctaacat
     6181 cttgtactag gttattatat tcaacatccc aagtacacca atcttttaac atagatgctc
     6241 ttactgattt agtagtagat agtggtcctg gtgtaagtaa tatgtaatca ttttctggta
     6301 caaaatctga tttaatagtt tcattctcta tttttattag tatatcttct aactcagcca
     6361 tagtttctat tacaaaatgt gcacctgcct ctttaaattt ctttgaaact atactcatct
     6421 tagcttttaa ttcttcctta tccatgttct ctacttcttc ttgtgtaagc cctaactcac
     6481 ttgaaccttt tattacagca acactccaca ttcctgcatt tacgccttct tttacatcac
     6541 ttattgtatc tcctactttt accatagaac tcataggaga cacccctaaa gcttcagcat
     6601 ttttatagca catccaagga taaggtcttc cttgagatac ttctgatggt gttacaagaa
     6661 aatcgggtga gtatcctttc tttgctgcac ttggttcaac tatgttcatc atctctcttg
     6721 tataacccgt tgtagaacct atttttaatc cattttttct caacttttca atagtttcaa
     6781 caacatgagg aattggagtc gtatactctt ctaatgtctc aaataacatt ggctcaaatt
     6841 cagcataaag ttcatttaca tcatcttcag ttggcacttt accaaactta tctgaccaaa
     6901 tattctttat tctatccatt tcacacattt ctcttatatg gtctattttt aattttccca
     6961 taggttttct tgcttcttcc attgttacat ctatacctct tcttttaaat atctctataa
     7021 atacattaag aggtgcaaaa catccataat ctactgttgt tccagcccaa tcgaatacta
     7081 ctgcttttat tttttctcca tatatctttt tcatatttat agcctccata gattcatttt
     7141 agaatttttg tgtttttaat tgtttttact tttaaagtat aactttcata tgttaattat
     7201 acatcatatt taggttaaat atatattaaa tttctgtttt tagttgtatt taattgtttt
     7261 tattttgtat catatttcca taaaatccta agttacaatc taaaatttac tttctaatct
     7321 taatctatga actgactata ttttatgaat ttagttgtat taagcatagt tgtattatat
     7381 aaaactaagg gtttattttg cttctatcca tgttatattt atctcattta acttatcctt
     7441 ccattcattc ggaggttcta catcacaaat aacaaaatct aattcctcta aatctgctat
     7501 cttatacata ctagcaattc ctattttaga actatcacat aatacaaaac tttcctttga
     7561 attttttata tattcttttg acaacaatgc cttattttgg tctatactac taattccaaa
     7621 actatcaagt ataccttcac tagatataaa agctttatct acgtataagt ttttcatagt
     7681 atctattgac attggacatg ctgtcctttg gtgttttaaa tttacttttc caccaataaa
     7741 tataacttct ccatcaaaca aaccttgatt ctcataagaa atcaattttg atagaactgg
     7801 ataagagttt gtaataattt ttaaattgtt tacagatatt atataatcta caatctgcaa
     7861 attggtagta ccttcatcta tgataattga ctcattgtca tttacaaact tagctgcgta
     7921 tttagcaata ctttgttttt tatctaggtt agtattgttt ctctttatat gttctggttc
     7981 aatcactcca taatttattt ttatagcacc accatatacc ttttttaatt tattttcatt
     8041 ttctaattct tccaaatatc ttcttattgt ttctgatgat acttctaatc tttttactaa
     8101 ttctttagta tttaccttcc cttttgaatc taataattta agtatttctt tttttctatc
     8161 tatcgaattt aaagacattc attttcctcc taaatataat atatttttct cctataatat
     8221 tacaatgata cctaagattt atgaaatcat atttatgtat taaatttttt acttaattaa
     8281 agttattttc aaaagacttt gtattatcat taaaaaagtc catcaaatat tagtatcaga
     8341 tggactttgt aaaattttat tttataaatt aatatttaaa gtctaactac taatttattt
     8401 tcttgtctcc aagaatttta ctaaattatt tacagtagac atatcttttc tctctaaatc
     8461 agttggttga agctctatcc ctaatctatt ttcaatttca agtaaaactt caattatagc
     8521 taatgagtct aaaagttccg tctcaaataa attaaggtct aaatcttctc ttatctcatc
     8581 agtccctaat acatcttcaa atatttctat aactgtttct tgcataaatt ttcctcctta
     8641 aaattaagct aaataacctg agaatatcag caatccaaaa cacacaatat ggaatgtaat
     8701 gaaaatctgc actctctcaa accatttatc ttttttatgt tttttataaa atttagattt
     8761 tcgctgatat atatcagtta acacaagtgc caatccttgg tatacaccat aagcaacata
     8821 ataccaagtt agaccatgcc aaaatcccat tgttatcatg gttatcatct gagccacatg
     8881 agcagcagta gtccttttct taaatctttt ctttctcatt gatgacataa caaatctaga
     8941 aaaaatataa tctccaaacc atcttgaaag acttatatgc catcttgtcc agaactcttt
     9001 catatcttta ctgataaatg gcttgtcaaa gtttataggt acttgtattc caaatatgta
     9061 ccctgtacct atagcaaata aactatatcc tgcaaaatca aagaacaggt ataaactata
     9121 tgcgtacata taacttaaaa tatttataaa actcatatct ttaggtattc ttgataccca
     9181 atatgtattt atcaaaaatg ctataacaaa cttataacct actcccatga caatattttt
     9241 tattcctggc agtaagtatt cttctatata ctcttttcta gagatgtgtt tttccaagtc
     9301 ctgttcaaat cttcttgacc tatcaatagg tccagaactt aaagttggaa aaaataacat
     9361 aaaataaagc atctttgaaa ttttaacttc ttttatagct ccatcataaa tttcaataac
     9421 catttgtata gttctgaaat ttaagtatga tattccaata aatccaatta ttccaaaaga
     9481 agtaactgga gatattttat ttattattat tgggagcatt gatgcaaaca agaatcccca
     9541 atatatgtat ttatttttag tttttcttct tacatattca tatcctttaa ctattattac
     9601 ttcaagaata ataaatatta ccaaatactt tagttggaca tcaattccta ctattaagaa
     9661 tagcataaac aaacttgcca acataccata atactttata ttcttgccca ttagacctaa
     9721 aattactgct ggtattgatg ttaataataa tatataaaga taaaaataat ctccatactg
     9781 tgaaaaaatc attaaatttc ctccataagt ttctttctgt ctattttacc attgatattt
     9841 gttggaaact cagagattat tgaaatattt cttggaatca tatatgaagg tatatacttt
     9901 ccaagttcct tttttattat catcccattt ttaatattac ttaaatcatt cttttcattt
     9961 aactcaacaa taccttttaa gtaagcaatt ttttcgtcct tatatactgg taaaactact
    10021 gcatttttta cattatgtac ttttctcaaa ttattttcta tatcttctat ttcaattcta
    10081 aatccattta atttaatctg aaaatctttt cttccacaat aatatatatt tccatctaaa
    10141 agatatccca tatctccagt tttataagct ctccacttta caccatctat ttcatcatag
    10201 aaaaatactt catcagtctt ttctttatta ttgaagtaac ctttagaaac tgatggtcca
    10261 attattataa tttcaccctt ttcattttct ttaagttcat ttccatcttc atcaagtatt
    10321 tttattttac aatttgacat agggtatcca actggaagac ttttttcatc atctatagct
    10381 ttttgagtca tatcatttac acttacacca acagtagcct cggttggtcc atatccattg
    10441 ataattcttg tgtttgaaaa tctactcata agttctttag taagattttt tgaaagtgct
    10501 tctcctatga atatcattga ctcaaggtta ggaagcattt tactattaaa ctctttttca
    10561 gttatacata ctcctgcaaa agaaggagtt gacacccata cagctatatc tgagatacta
    10621 aattgtctaa atagttcttt atagtctgct aatacatctt ttgatattga aaataatgta
    10681 gctccatgga taagaccagg gtatattgtt gtaactgaaa ggtcaaaaga atatgctggt
    10741 tggttcatta ttactttttc acttccatct atgtttagat atgggcttat ccaatctgaa
    10801 aagctatcta aattgtttga acttatttga accccttttg gctttcctgt acttcctgaa
    10861 gtaaatagta tatatgcatt ttcatcatct tttacccagt tttctttatc taatgatttt
    10921 ccctgatatt catttattat atcatttaat ttatccatat caattacatt gatatctcca
    10981 aaatttcttt catcactaaa attaaatatt acttttggtt ttatctcttt agtgacttca
    11041 aaaactctat caattggaaa actaatatca agaggcacat acgctctacc tgattttaaa
    11101 gctcctatca tacatgccat tatcatgttt tctttatttc cataaattac tataggagta
    11161 tcttcttctt tgtatacatc ctttagaaat actgatatag catctgaata ttcatttaaa
    11221 tctttataag aaagtttatc tccattacac attagtgctg ttctatctgt atttgaatat
    11281 ttttttattc cttcaataat tttcatataa gaatgctcct ttaaaatccg ttataaataa
    11341 atggcaattc tttaaatgga gtaaatgtta gaactcctat cgccaatatt ataaccatag
    11401 ttaaacaaat actagttaac aaatctttat tgttctttaa atattttaaa taatctctca
    11461 cagacatcta cccatccttt cgtaccaaga tgcattacat cccttaaata atacttatct
    11521 gaccctttat ctttaaggtt tagaacttca aagcctttgc tttctgctat tttttgtgct
    11581 ttatcgtagt actgatttct ttctttttca gaaataccag tcaaattata gaatttatcc
    11641 atacttggga ttaatacaac aactggctta atacctaagt cagtacatac atttagcatc
    11701 agtttataat tttcaaactc cttagatgtt aataaattta catctttgtc tcttcctttg
    11761 tattgctcta taccatcttt aaaatgctct ttataatagt acttatcaat atttagtgga
    11821 tttttaccaa ctcttttttt agcatcttca atggctttct ttctctcata tgaccaattt
    11881 attggtcttt ttctttttgt tgctctcttt ttatctagct taattaatcg tttataaaga
    11941 ataccctttt ctttaagagc tatacagtac tttcttcctt gaaaataagg ctctaaaagc
    12001 accttttcag ctttttcagg aaatgtctta ggttcatata gcttagcata taatgcttct
    12061 gctttatact catcacttcc ccataatagc ttacttgatt tttttgcata ttcaatctta
    12121 ttttgtttag atatttttgg attatctaaa aatcgataaa attgtattgg tgaaaatcta
    12181 gactgataat ggtgacttgt gactccgtct ttttccataa accattgcat agaaattaac
    12241 aagacaactt tcttattatc aatattagga ttcatacttc ctaatattgc agcatcttgt
    12301 aatgtctgag tataggctct cccaattgca aacaccttat ttttactcct atttgtatta
    12361 aaatagtact ttggatgttg ttttgttgaa ttactaagtt ctgatgaccc caaaatcata
    12421 atatcctttt ctcttaaaaa atgattattt gctgtaaccc ctttatcttt tatatcactt
    12481 aaagtatcat ccataattgg aagtagattt ttctccctca aaagttcatc agttttagaa
    12541 tcaagaaatt tgtctaaccc aaataaaaat actacgccta ttataaaagg tgtaataaag
    12601 tatatcaatt ttctcatatt ttctctcctc taaaaatatt caaatttatg ttattattaa
    12661 tcatattagt tttgatatgt atattcaact acaaaattgt aataaaatcg tcaaaacttt
    12721 ttttgatact gttacaaaat tgtaaaaaaa aagaaaaaaa caccaaaaat aaatttcttt
    12781 ttatcacttt ttcatactta taatttgaca ttttaacact tggctaagta tacaccttgc
    12841 cttaacttaa aattaaattt atttaagaat atatattata aattcttata ttttctaata
    12901 taagctatat actatcagct ggataaacaa tactactttg tcttcttatc tcatccataa
    12961 tttccattac tattattgaa ttttcatgag aatttatatt tgattctatt ttattgttat
    13021 ttataagact tataaactct acaagttcat aatacattcc ttctatttct ctaggctttt
    13081 cctctgcttt ttcttttgga atagatatat cttcttctct tccatctctg tatttaataa
    13141 tagctttttc aaatagatta agcttttcaa ttattatact tccctcttct ccttgtattt
    13201 cagatggtat ataagaatca gctactttag aatactgaat tatcgcatcc atatcatcat
    13261 attgaaatac agctgaacct tctccatcca ctccagtttg aagtatatga gaaactgcct
    13321 ttacagtttt tggagcacca aataaattca ccataggatg tatacaatac actcctatat
    13381 ccattaaagc tccatttgac aactcttttt taaaggcatt ttctataatt ccatttttat
    13441 atttatcata tcttgaagaa tactgacaat agcttccaaa aaatcttctt attttcccta
    13501 ttttatacaa gttttcttta actgctttaa agtttggaac acatgtaatt ctcatagctt
    13561 ccataagcaa tacattatta tctttggctg tttttatcat tgatttgact tcttttaaat
    13621 tagatgctaa cgacttttca caaagcacat gttttttgtg ttttaaacaa gtaatggctt
    13681 gctttgaatg taatgcattt ggagaagcta tatatacagc atctatatcc ttcgatttag
    13741 ccatttgttc taaatcatca aaaaaaatac ttgctccatg tagagttcca aattctctag
    13801 ctttttctaa atttctagaa tatacagcaa ccaattcaaa atctttaacc ctagatgcag
    13861 ctcttagaaa tatatttgct atattgcttg tcccaacaat accaaatctt attttaccca
    13921 tcataaatca ctccccattt tctacacttt attttaattt taataaaaaa ctttacaact
    13981 tatagatata ttataaaata attttatcaa ataaaaaaga aagctaattt taaatgattt
    14041 caccatttta acatagcttt cttttaacta caatctaaat tcaacttata tttttaaagt
    14101 tatctttcta ctatatcttt atttcccctc aaaaatttta tagtaagaat ttcatccaca
    14161 aacaatgtta ctaaaagtat agttacaaga attggccaat aaggtattat aagactatat
    14221 aaactatcaa ctatatacac ttgaaaatat ctaactccaa taaatgtcaa tatagtccaa
    14281 tatacagaaa actttagaca tactattcct ctactattgt acttataatc tgaataatcc
    14341 caatagacct tattaaaata tactttcata agtattcctg taatatattc tactactgtc
    14401 ggcactacta gacataataa aagcaatgca aatatattat tggggtcaat aaatcttgag
    14461 acctctatta taatcgacat tgcaattgca tacattggtt taaatggacc atttaaaaat
    14521 ccatcttctt gaaaatgccc ttgtttataa taactatata agttttcaat tatccaacct
    14581 ataaaaccat acaagaaaaa attaaataaa aaatataata gagaacctac attatccatg
    14641 aatattcctc ctagctgttt atacttattt tttctcatat tcatggattt attctaaatc
    14701 aaagaaatta tatttaattt atttaattaa tactttatat tatagattgt gacattcttt
    14761 agagttcaaa ctttttaggt attctctaac ttccagtaaa ttttcaagta tcttatgtga
    14821 ttgtgattta atttgctcat ctggctcttt taaatctggt acatttatac atcttatccc
    14881 accattgtat gcagcttcaa ctcccatagg cgaatcctct atgacaatac aattttgggg
    14941 attaacattt atctttttag ctgcttttaa gaatatctca gggtttggtt tagagtttac
    15001 aacatcatct ccacaaacta tagcatcaaa gtaatctttt aaatttgcct tagctaatct
    15061 ctttactgct ctttctctct ttgttgatgt tgcaacagcc attttgtatc cattttcctt
    15121 taaaaaagag attagttcat tgactcctaa tttgatagga gctcccttcc tctccataaa
    15181 ttcaatcata tttttagttt tttcgtcata taaatctatt attggtacag aactatcgta
    15241 tatatctgta agaccttcta ttattccttt acgatttctt cccataactg atgtataaat
    15301 ttccttagtc atagtatatc catacttttc aaacgtctcc atccaaaatt caagagaaat
    15361 tctctctgag tcaaacaaaa ctccatccat gtcaaaaata attccttcta ctttttgcat
    15421 acaattcctc caatattttt tgatataatt atattacact ttttatgatt aattttacaa
    15481 ccctcaattt atccaattct aatattgtaa aattgtaatt ttcaaaagtt acgctttggt
    15541 ttactttaat atttgaacca agcatatagg atatccaccc acctatactg tcaaatccat
    15601 catgctctat atcaagtcca aaatacttat taatatagtt gatagattca gttccatcaa
    15661 ctaagtaaga acctgctcct attttcttaa tatgagtctc ttctttgtca aattcatctt
    15721 gaatttctcc aactatctct tctagtatat cttctattgt taccacacca gatgtaccac
    15781 catattcatc cacaactata gcaagttgaa gtttttcctt tcttattctc tcaagagctt
    15841 tatctatagt taaattttca gatatatata taatatctct caatatttct tctagttcaa
    15901 ttttattttc atttatcttt tgattgtata aatctcttat atgtacaaaa cctaatatat
    15961 catctttatt ttttctgcat actggatatc ttgtaacacc ttcctctttt aaaatagcta
    16021 atatcttttc ttcagaatca ctttcatata tacataccat atcagttcta ggaaccatta
    16081 tctttctaat tttcttttct tcaaattcaa aaatattatc aactaatctt tgctctgatt
    16141 catctataag tccactttta taactttctt ctactaatag tcttatttcg tcacctgtat
    16201 ggggttcatc aacctcatca gcttgtgaat atccaaatgg tttaagaaat aaatcagtac
    16261 ttaagttgaa aaaatatatt attggatatg ttaacttata aaatcctact aataaaaaag
    16321 atgtactcaa cattattttt tctgtattat aaagtgctaa agctttagga accaactctc
    16381 ctattacaac ctccatcatt gttataatta aaaaagaaat ggaaattgat atagtatata
    16441 taatactttc actaagatta aatacactta ctattggtaa aattaactct ttaactgtag
    16501 attctcccat ccaacctaat gcaagtgaac aaagtgttat accaagttga catgcagaaa
    16561 gataggaatt taagttgtct tttattattt tacatctttt tgcattatta ttaccttcag
    16621 ttatcatggt atcaatccta gaactacgaa gttttaccat agcaaattca caagctacaa
    16681 aaaaagcatt tatcaaaaca agcattacta taagtgttac ttttaataac tcccgcataa
    16741 agtattggtt cttataatgt aagaaatcta taagaactca aagttccccc cttatattta
    16801 taaa
//
LOCUS       DACTZW010000088        16684 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.088, whole genome shotgun sequence.
ACCESSION   DACTZW010000088 DACTZW010000000
VERSION     DACTZW010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16684)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16684)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16684
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.088"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(18..1094)
                     /locus_tag="JAM15_15480"
     CDS             complement(18..1094)
                     /locus_tag="JAM15_15480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HAT6799652.1"
                     /translation="MSKKLFIPGPIDVKEEVLQKMATPMIGHRGKDASMLQKSISEKM
                     QKLFYTNNTILLSTSSGTGLMEGSIRSCTSKKAAVFSCGSFGDRWYKMAVANNVPADI
                     FKVELGEATTPEMVDKVLSTGEYDLITVTHNETSTGIRNPIEEIGEVVKKYEDVIYCV
                     DTVSSAGGIKVEVDKIGIDICITSVQKALGLPPGMSICTFSQKAIDRAKQVPFRGVYL
                     DLLAMYEYLIKKNYQYPSTPSLSHMFALDFQLDNILDEGLDNRFNRHEDMANLVRNWA
                     KKHFQIFTNENHLSNTLTVIENTQGISVSNLNSKLQERGFQIANGYGDLKEKTFRISH
                     MGDYTVEDVQELLDNIDDILGFNK"
     gene            complement(1467..1982)
                     /locus_tag="JAM15_15485"
     CDS             complement(1467..1982)
                     /locus_tag="JAM15_15485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HAT6799653.1"
                     /translation="MDFLAKYKVLKKQNSSKSCLVCGTQNELGLKADFYELENGELVS
                     ICNTKDWHQSYPGRVHGGMSAAILDETIGRAVSINDDQIWGVTVSLELKYKKPVPTDA
                     TIKVVGRITKENRKLFEGTGEIILPNGDIAVTATGKYMKMPIGQIAEGDFSNEEWFFE
                     ESKEKVEYIEL"
     gene            complement(2345..3415)
                     /gene="leuB"
                     /locus_tag="JAM15_15490"
     CDS             complement(2345..3415)
                     /gene="leuB"
                     /locus_tag="JAM15_15490"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015390422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HAT6799654.1"
                     /translation="MNCNIAVIKGDGVGPEIIDEGIKVLNKICCKFNHRFDCEYVLAG
                     GCAIDEIGEPLPNKTVETCRKNEAVLLGAVGGPKWDKCKGDKRPESGLLKLRESLGLF
                     ANLRPATMYESIKEASPLRTDIVEKGIDFVVVRELTGGIYFGERGRKIIDGIENAYDV
                     EIYNENEIRRIGKRAFEIARNRNKKLISVDKANVLESSRLWRSIMEDLAKEFEDVELS
                     HMYVDNAAMQVVKDPSQFDVIVTNNIFGDIISDEASMITGSIGMLPSASLREDSFGMY
                     EPIHGSAPDIAGKDIVNPIATILSVSMMLRHSFNLEEEAKCIEDAVQSVLNKGYRTID
                     IYNGVGNVVGTRAMGELIVNEI"
     gene            complement(3422..3913)
                     /gene="leuD"
                     /locus_tag="JAM15_15495"
     CDS             complement(3422..3913)
                     /gene="leuD"
                     /locus_tag="JAM15_15495"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020005769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HAT6799655.1"
                     /translation="MIANGSVFKFGDNIDTDVIIPARYLNIADYKELATHCMEDIDDK
                     FISKVKKGDIIVATKNFGCGSSREHAPIVIKESGVSCVIASTFARIFFRNSINIGLPI
                     LECEEAANNIDEGDNIEVDFSTGVIKNITKEKEYKAEPFPEFMQNIILNEGLINSIKA
                     NRG"
     gene            complement(3928..5205)
                     /gene="leuC"
                     /locus_tag="JAM15_15500"
     CDS             complement(3928..5205)
                     /gene="leuC"
                     /locus_tag="JAM15_15500"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HAT6799656.1"
                     /translation="MGMTMTQKILAKHAKLNEVKKGQLIEADLDVVLGNDITSPVAIR
                     EFEKLGIEDVYDKTKVVMVLDHFTPNKDIKSAEQCKFTRSFAKSKGVVNFFDVGDMGI
                     EHVLLPEKGIVTAGDVIIGADSHTCTYGALGAFSTGVGSTDMGAGMATGKCWFKVPGA
                     IKFVLKNKPNKWISGKDIILHIIGEIGVDGALYKSMEFCGDGVEYLSMDDRFTICNMA
                     IEAGAKNGIFPVDDKTMEYINSHKCSTITKDVNIYEADEDAVYDEVYEIDLAELKETV
                     AFPHLPENTRTVDEIDKDIKIDQVVIGSCTNGRISDLEVVAEIMKGKKVADGVRVMIF
                     PGTQKVYLEAIEKGYITTFIEAGAAVSTPTCGPCLGGHMGILAAGEKSISTTNRNFVG
                     RMGHVDSEVYLASPAVAAASAITGKISKPSEII"
     gene            complement(5162..6904)
                     /gene="leuA"
                     /locus_tag="JAM15_15505"
     CDS             complement(5162..6904)
                     /gene="leuA"
                     /locus_tag="JAM15_15505"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HAT6799657.1"
                     /translation="MKCGKYKKYDKMQIVNRKWPDNEIFKAPIWCSVDLRDGNQSLPT
                     PMSVNEKVRMFKMLIDTGFKEIEVGFPSASNTEYTFLRKLIDENMIPDDVTIQVLTQS
                     RAHLIEKTFESIKGCKKAIIHLYNSTSVLQRDVVFNMSKQEIIDIAVEGAKLFNEEVK
                     KYPETEFTFEYSPESFTGTEMDYALEICEAVIDVWKPTPQKKVIINLPSTVEMATPNV
                     YADQIEWFCKNISCRDSIILSLHTHNDRGTCTAASELGLLAGADRLEGTLFGNGERTG
                     NMDIVNVGLNLYTQGIDPELDFSNIDKIIGIYEDCTKLMVHDRHPYAGNLVHCAFSGS
                     HQDAIRKGMIAMKNRDNDYWEVPYLPIDPHDIGREYKEIIRINSQSGKGGAVYIMETD
                     YGFMIPKNMHSDFGNVVKMESDRIGEELSSEAIFNLFKKEYIEVESPYKVKKYKIKSM
                     DELNYENDDSNDTNMIEMTARISYMGNEQRIVGIGNGPVDSFNNALKQCGMKDYKFRY
                     YWEHALEEGSHSRGVAYVGIEHNNEVYFGVSISENINTAAINALMNAINKSYIEEEIK
                     NGDDYDAENISQTC"
     misc_binding    complement(7029..7275)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(7423..7869)
                     /locus_tag="JAM15_15510"
     CDS             complement(7423..7869)
                     /locus_tag="JAM15_15510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799658.1"
                     /translation="MSKNKFIYMNYYDNGYFKKGMTIYMVLALIILATIFIYSTTILY
                     ILCIITAVFLFKQGRDFSNKYEGKVYITLDNHSILINNQCIFSIKSKQSQKFNYKIIE
                     KIEVVKNILNIYTDESNYKIRLRALSLEDEKKLLNIIDEKMKKFKA"
     gene            complement(7890..8609)
                     /locus_tag="JAM15_15515"
     CDS             complement(7890..8609)
                     /locus_tag="JAM15_15515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HAT6799659.1"
                     /translation="MKKSIMDVHCHTLISGHAHSTFKENVEEASKKNIKYLGISDHGP
                     NMPGGPHPFYFYNLHLLPREVQGVKILRGIEGNIMDYSGNLDVQEDMLQHLDYIIASL
                     HRPCIASGTKEENTNAILKVMDKPKVKIIGHPDDSRYPLDYEPIVKKAKDKNILLEIN
                     NSSLSSNSHRTGTWENVSHMLTLCKTYGARVILGTDSHICYSIGEFENAEKVLEAVDF
                     PDELVINYHEDEIIEFFDINF"
     gene            complement(8727..10001)
                     /locus_tag="JAM15_15520"
     CDS             complement(8727..10001)
                     /locus_tag="JAM15_15520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HAT6799660.1"
                     /translation="MFIMENDLTMQELLDQQEQVFSKVKVGELTTGKITAVRNDEVQL
                     GLDYGFDGIIPISELNIEKNQYIEDIYHMGDEITAVITKVSQKDGTITLSKLQLDKRN
                     DFAELQKAYDEHRIITVNVEKNIDKGVFANYNTYTFFIPISQLDTKFITDTSKFVGLN
                     LEVYIKELDVRKNRLVASHRDVLQERINKEREERRAQIKAEKEAERARIKQEREEEKA
                     RIKAAKEDLFNSLEVGQKRDGKVTKIMPYGAFVDIGGIEGLAHINNLAWTRVESVEDV
                     VSEGQEVEVYVLDVNKETKKIALALKDINNDPWDLIAKEVQIDDVVNAKVLRIIEKGA
                     FVQIKEGVDAYLPISELSDTRVAKVTNVVNIGDEVKVKILDFKPKTKRMLVSIKEATR
                     EPEEDITEYLEVEESLGSIGELFKDKFKDLEV"
     gene            complement(10201..11568)
                     /locus_tag="JAM15_15525"
     CDS             complement(10201..11568)
                     /locus_tag="JAM15_15525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HAT6799661.1"
                     /translation="MENSNTNLGSESVGKLLFKLATPAIIAQIVNVLYNIVDRIFIGR
                     MENGEVAMAGVGVAFPIIIIITACSYLIGMGGGPLAAIKMGEQNNDEAEKIMSNSFSV
                     LVILAILLTIGFKIGKEPLLWMFGASESTIRYSMDYLNIYLIGTVFVQISMGMNTFIN
                     TQGFATTGMMTVAIGALINIILDPIFIFGFNMGVKGAALATIIAQGVSAIWVLMFLFG
                     KKSILKIKKKYMIPKASIILPVLGLGISPFIMQSTESLVLIALNSKLQMYGGDLAVGS
                     MAIMSSIMQILMLPNMGVTQGAQPIISYNYGSGQLDRVKKTFKLCLLSCFTYSTILWL
                     LLMIFPAFFVSIFNKNPQLLSMTSWSIKIYFAGAFMFGIQIACQQTFLALGKATISLV
                     LALLRKIVLLIPLIFILPTFFNEKLFAVILAEPVADITAATITAISFFIFYKCFLSKP
                     KAIKE"
     gene            complement(11818..12255)
                     /locus_tag="JAM15_15530"
     CDS             complement(11818..12255)
                     /locus_tag="JAM15_15530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small multi-drug export protein"
                     /protein_id="HAT6799662.1"
                     /translation="MGYLHILILSMVPVTELRGAIPIGIAMGLNPIWVYVFSVIGSTL
                     VSIPLILTFRHVLQFLRGKKLFKGIADVIDRKINSRMKKLKSVSIIGIILFVGIPLPT
                     TGTWTASAIASILKMRIKDAFMGVFLGNLLSGVIVSALSLHII"
     gene            complement(12287..12916)
                     /locus_tag="JAM15_15535"
     CDS             complement(12287..12916)
                     /locus_tag="JAM15_15535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HAT6799663.1"
                     /translation="MKKSVLLLDVDYTVINTDSMIDFFIYSLKNKTFKTIIKLPYIIF
                     ILFMYLIRMIPLKKAKEAIFYPIVDFSEEDLKKFFDDCIMKKINESMKKVIYKNKEED
                     NVIIMITASPYAYMKYFKYYGLADEVIGTEFFYENSRYKNQFIGENCKGIEKVKRIKA
                     VLGKLGIEIDYENSYAYSDSKSDLPMLSLTKNAFLVSKKDGEVIEQINS"
     gene            complement(12950..13837)
                     /locus_tag="JAM15_15540"
     CDS             complement(12950..13837)
                     /locus_tag="JAM15_15540"
                     /EC_number="2.4.2.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decaprenyl-phosphate phosphoribosyltransferase"
                     /protein_id="HAT6799664.1"
                     /translation="MKQTNTSIRLLTKISDYIKLMRIKQYIKNFFVFSAIIFSNNILN
                     INLFLNTFIAFVCFCLMSSSVYALNDAIDMDKDKKHPKKCNRPVASGRISKKSANILF
                     VVLALISVCLSTVVSFNLSIILSLYLINNILYSLKLKNIILLDVFSISLGFILRVYAG
                     CVAISVSLSNWIILCTFFLSLYLALGKRKKEIETLRDDAVEHRKILEDYDIENLNQMM
                     IVILSSTIVCYALYSTSNPEKPHMIFTTIFVVYGVLRYNYIINTTNENNPTDIVLKDN
                     ALKINVILWIITCLIILIF"
     gene            complement(13866..15104)
                     /locus_tag="JAM15_15545"
     CDS             complement(13866..15104)
                     /locus_tag="JAM15_15545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799665.1"
                     /translation="MDGDILMSKILKYKNEMFLFILVVITYLIITKIFFSKTTIFYDL
                     NNTYDVLLDTDTGVLFNLNVFAISQDNSKHILFSAIISIFAYPIYLFCTSIANPGTTD
                     FNSAYGFGLICLQIITSAMSITLVFNHIKKIKMQRLTLILLTMIMIFSFPQLFMTLNV
                     ERFIYSQFSLIFFIVIANKMKGKNSYLVELAAIPLFGITISNIYLYFFNMIFEFKLKI
                     GKMLKHLITFILMAYICVVSTKSYESFMNLGNVIQYDTKFISGEPILEKIAMIIERLL
                     YSVFYFPGASIKKGLFLQNGEVATIPVILTLLALCFCVLSVIENSEKRVPKLCMGIII
                     FNLTLHGIVGYNLVNSSIMAINFSFAVIILLAYFTKALRKNEKNMYNIFLSLLLVTIV
                     ISNVNGFIEILNIGIKSYPV"
     gene            complement(15488..16630)
                     /locus_tag="JAM15_15550"
     CDS             complement(15488..16630)
                     /locus_tag="JAM15_15550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HAT6799666.1"
                     /translation="MRYVEYGKTGKMVSVVGYGGLRFDLEKSNQENADLVKYAYEKGI
                     NYFDTAPGYCDDRSEDIFGLAFRQMIKEGKTDFYVSTKEKPKACDTSEKAIEAVKKSI
                     ERLGVSKINFYHVWNIRKMEHYELAMRPGGQYEGLLKCKEEGLIDHIVFSSHQPGDEV
                     IDILSENKFEGVTMGINILNFPYRLKGAKYAVDNGYGVVAMNPLSGGTIPKYNKELSF
                     LSKDGESTIESALRFNIGISQISISLIGFNKKQDIDDACKIADENRIYSDEDIHDIET
                     RLNKNMNEICTGCGYCKVCPKGINTPAYMLFYNEKQMFKKSDEEMTKLVYGLGHWNYT
                     MNSKAKAKECISCGKCEVECTQHLPIIDRLKEIKKWEEDGANSVKV"
BASE COUNT         5407 a         3041 c         1739 g         6497 t
ORIGIN      
        1 tacatatttt tacaatatta tttattaaaa cctaatatat catcaatatt atctaataat
       61 tcttgtacat cttcgacagt atagtcaccc atatgtgaaa ttctaaaagt tttttctttt
      121 aaatctccat agccatttgc tatttggaat cctcgttctt gtaattttga atttaaattt
      181 gatacactaa taccttgagt attttctata acagtaagtg tattggataa gtgattttca
      241 ttggtaaaaa tttggaagtg ttttttagcc cagtttctaa ctaagtttgc catgtcttca
      301 tgtctgttga atctgttatc taggccttca tctaatatat tatctaattg gaaatctaaa
      361 gcgaacatgt gagaaagaga tggtgttgaa gggtattggt agtttttctt gattaagtat
      421 tcatacattg ctaacaaatc aagatatact cctctaaaag gtacttgctt agctctatcg
      481 attgcttttt gagaaaatgt gcaaatagac attcctggtg gtaatcccag tgctttttgt
      541 actgatgtta tacaaatatc tattccaatc ttatcaacct cgacttttat tccaccggct
      601 gaacttacag tatctacaca gtagattaca tcttcatact ttttaacaac ttctccaatt
      661 tcttctattg gatttcttat tccagttgaa gtttcattgt gagttacagt tattaaatcg
      721 tattctccgg tagaaagcac cttatcaacc atttctggcg ttgttgcctc tcctaattca
      781 actttaaata tatccgctgg gacattatta gccactgcca ttttgtacca tctatcacca
      841 aaggatccac aggaaaatac tgctgccttt ttggatgtac aggaacgaat ggagccttcc
      901 attaaaccag ttccggatga cgtggataaa agtatcgtgt tgtttgtata gaatagtttt
      961 tgcatctttt cacttatact cttttggagc atagatgcat cttttcctct atgtcctatc
     1021 attggtgtag ccatcttttg caagacttct tctttaacat caataggacc aggaataaat
     1081 aatttcttac tcattataat tccccccttt ttagtttgta atatggatag cgtttttact
     1141 gtccttattt ttaataacta taatatcaag ctgaattaac tatgtcaaca taaaatttat
     1201 tttttacata taatttattt tatatatttt atgaaaacat tcattttcta cattttcacg
     1261 agtctgaatt ttctgaatta ttctctcaaa aaaaatatac tttttatcta tataaattaa
     1321 tttttttagt atgtaaattt gacgctatta cgataaatct ttttagtata actaatttat
     1381 ttttatcttg tatttttatt gtatttttaa attttatttt ttctaaatat aaaatttatg
     1441 ttttaaaata taaaattttt atttaatcaa agttcaatat attccacttt ttctttcgat
     1501 tcttcaaaaa accattcttc attagaaaaa tcaccttctg caatttgtcc aataggcatt
     1561 ttcatatact ttccagttgc tgtcactgct atatctccat ttggtagaat tatttctcct
     1621 gtaccttcaa ataattttct gttttcttta gttattcttc caacaacttt tatagtagca
     1681 tctgttggta ctggtttctt atatttcaac tctaaagata ctgttactcc ccatatttgg
     1741 tcatcattta tacttacagc tcttccaata gtctcatcta atattgcagc agacatacct
     1801 ccatgaactc tcccaggata actttgatgc caatcctttg tattacaaat tgatacaagc
     1861 tctccatttt caagttcata aaaatctgct ttaagtccta gctcattttg tgttccacaa
     1921 actaaacaag atttactact attttgcttc ttcaaaactt tatactttgc caaaaaatcc
     1981 atctcctaac cgacattagt agtcgcttaa tattaaataa ttctaaaata tattatataa
     2041 tattaataaa atccctgcaa acttctaata ataaaaatag gctacttcaa tatgataagt
     2101 ttaatttaaa gtattatttt ccaaaaaata actttatcaa aatagaaact caaagtagat
     2161 ataagcctct ttttcgttat taaaatagta aaaatatatt tgacttaata taaaaaagag
     2221 tgtctcatta actaataaag tttattttga gacacccctc ataaaacaaa ttatactaca
     2281 atagattttt actaattcta caagttatat atttaaatta tattattcaa attaaactat
     2341 aattctaaat ttcatttact attaattcgc ccattgctct tgttcctaca acatttccca
     2401 caccattata gatatcaata gttctataac ctttattgag tacactttgt acagcatctt
     2461 caatacactt agcttcttct tctaagttaa aactatgtct taacatcatg cttacagata
     2521 gaatagttgc aattggattt acaatatctt ttccagctat atcaggcgca cttccatgta
     2581 ttggttcata cataccaaaa ctatcttctc taagtgatgc tgatggtaac atacctatag
     2641 aacccgtaat catagatgct tcatcagata ttatatctcc aaatatatta ttagtcacta
     2701 ttacatcaaa ttggctaggg tcttttacaa cttgcatagc agcattatca acatacatat
     2761 gtgacagttc tacatcctca aactctttag ctaagtcttc cattatactt ctccaaagtc
     2821 ttgaactctc aagcacattt gccttatcta cacttataag ttttttattt ctatttctgg
     2881 ctatttcaaa agctctctta ccaattcttc ttatttcatt ttcgttatat atttctacat
     2941 cataagcatt ttcgatacca tcaatgattt ttcttccacg ttctccaaaa taaatgcccc
     3001 ctgttaattc tcttacaaca acaaaatcaa tgcctttctc aactatatcc gttctaagtg
     3061 gtgaagcttc ttttatactt tcatacattg tagctggtct taaatttgca aataaaccca
     3121 atgactctct taattttaaa agaccagact ctggtctttt atctccctta catttatccc
     3181 actttggtcc tccaacagca ccaagcaata cagcttcgtt ttttcgacaa gtttcaacag
     3241 ttttattagg tagaggttct ccaatttcat caatcgcgca tcctccagct aatacatatt
     3301 cacaatcgaa tctatgatta aatttacaac aaattttatt tagaaccttt ataccttcat
     3361 ctataatttc cggtccaaca ccatcacctt ttatgactgc tatattacaa ttcatactcc
     3421 actaccccct atttgctttt attgagttaa ttaagccttc atttaatata atattttgca
     3481 taaactcagg aaatggttct gctttatatt ctttttcttt tgttatattt tttatcacac
     3541 ctgtagaaaa atctacttct atattatccc cttcatctat gttattggca gcttcttcac
     3601 attcaagtat aggaagccct atatttatag agtttctaaa aaatattcta gcaaaagtag
     3661 aagcaatcac acaggatact ccactttctt ttattacaat tggtgcatgt tctcttgatg
     3721 aaccacaacc aaagttttta gttgcaacta taatatctcc tttttttacc ttagaaataa
     3781 atttatcatc aatatcctcc atacaatgcg ttgctagttc tttataatca gctatattta
     3841 aatatctagc tggtattatt acatctgtat ctatattgtc accgaattta aaaacacttc
     3901 cattggcaat cataaatttt acctccctta aattatttct gatggttttg atatttttcc
     3961 agttatagct gatgctgctg ctacagctgg gcttgcaaga tacacctctg aatcaacatg
     4021 ccccattctt cctacgaaat tcctatttgt tgttgaaatg gatttttctc ctgctgcaag
     4081 tatacccata tgtcccccta gacatggacc acaagttggt gtagaaactg ctgctcctgc
     4141 ctctataaaa gtggtaatat accctttttc tatagcttca agatatactt tttgagttcc
     4201 aggaaatatc ataactctaa ctccatctgc tacttttttg cctttcatta tctcagctac
     4261 tacttcaagg tctgatattc ttccatttgt acaagaacct attacaactt ggtctatctt
     4321 tatatcctta tctatctcat ctactgttct agtattttca ggaagatgag gaaaggctac
     4381 tgtttctttt agttcggcta aatctatttc gtatacttca tcatagactg catcttcatc
     4441 tgcttcatat atatttacat cttttgttat agttgaacac ttatgtgaat ttatatattc
     4501 catagtctta tcgtctactg gaaagattcc attttttgct cctgcttcta ttgccatatt
     4561 acaaatagta aatctatcat ccatagataa gtattctact ccatctccac aaaattccat
     4621 cgacttgtaa agtgctccat caacacctat ctcccctatt atatgaagta ttatatcttt
     4681 accacttatc catttatttg gtttattctt caaaacaaat tttattgctc caggaacctt
     4741 aaaccaacat tttcctgtag ccatacctgc tcccatatca gttgaaccta caccagtaga
     4801 aaatgctcct aatgctccat atgtgcaagt atgagagtca gcacctataa ttacatctcc
     4861 agcagttact ataccttttt caggaagaag aacatgctct attcccatat ctcctacatc
     4921 aaaaaaattt acaactcctt ttgattttgc gaaacttctt gtaaatttac attgttctgc
     4981 actctttata tctttattag gtgtaaagtg gtctaaaacc atcactactt tagtcttatc
     5041 ataaacatct tcaattccta atttttcaaa ttctctaatg gctactggtg atgttatatc
     5101 attacctaaa actacatcta aatctgcttc gattaattgc cctttcttaa cttcatttaa
     5161 tttagcatgt ttggctaata ttttctgcgt catagtcatc cccatttttt atttcctcct
     5221 caatataact tttatttatt gcattcataa gtgcattaat agctgctgta tttatgtttt
     5281 ccgatatact tacaccaaaa tagacttcat tattgtgctc tattcctaca taagctaccc
     5341 ctcttgaatg tgacccttcc tctaatgcat gttcccagta atatctaaat ttataatctt
     5401 tcatgccaca ttgctttagt gcattattaa atgaatctac aggtccattt cctataccaa
     5461 caatcctttg ttcatttccc atataactta ttcttgcagt catctcaatc atgttagtat
     5521 cattagaatc atcattttca tagtttaatt catccattga ttttatttta tacttcttaa
     5581 ctttataagg gctctcaact tcaatatatt ctttcttaaa taaattaaat attgcttcac
     5641 tactaagttc ttccccaatt ctatcagatt ccattttgac tacatttcca aaatcagaat
     5701 gcatattctt aggtatcata aatccataat ctgtttccat tatataaaca gctcctcctt
     5761 ttccagattg gctatttatc cttataattt ctttgtattc tcttccaata tcatgagggt
     5821 ctattggtaa atatggaact tcccagtaat cattatctct gtttttcatt gctatcatgc
     5881 cttttctaat agcatcttga tgtgaacctg aaaaagcaca atgtacaaga ttacctgcat
     5941 atggatgtct atcatgtacc ataagttttg tacagtcttc atatatacca attatcttat
     6001 ctatattgct aaaatctagc tctgggtcta ttccttgtgt ataaagatta agtcccacat
     6061 ttactatatc catatttcca gttctttcac catttccaaa tagtgttcct tcaagtctat
     6121 cggcaccagc caataatcca agttcacttg cagccgtaca agttcctcta tcattgtgag
     6181 tatgcaaact tagtataata gaatccctac aacttatatt tttacaaaac cattctattt
     6241 ggtctgcata tacgtttggt gttgccattt ccactgttga tggaagattt attattactt
     6301 ttttttgagg agttggtttc caaacatcta tcactgcctc acatatttca agtgcataat
     6361 ccatctctgt tcctgtaaaa ctctctggtg aatattcaaa agtaaattct gtttctggat
     6421 atttttttac ttcttcatta aataattttg ctccttcaac tgctatatct attatttctt
     6481 gtttactcat attaaaaacc acatctcttt gaagaacaga tgtagagtta tataaatgta
     6541 taattgcttt tttacatccc tttattgatt caaatgtttt ttctataaga tgagccctag
     6601 attgtgtaag tacttgtata gttacatcat ctggaatcat attctcatct attaattttc
     6661 ttaaaaatgt atactctgta tttgatgctg atggaaatcc tacctctatt tctttaaatc
     6721 ctgtatcaat aagcattttg aacattctga ctttttcatt tacactcata ggtgttggca
     6781 gtgactgatt tccgtctctt aaatcgacac tacaccaaat tggagcctta aatatttcat
     6841 tatctggcca tttacgattt actatttgca ttttatcata ttttttatac tttccacact
     6901 tcatgttatt tccccctttt tctgtttttt tgtattcagt atacatcata tcgacgcaat
     6961 cctgcacaat tcataaggat aaatgtcaat tttatcatta gaataaaaaa aacctcatct
     7021 ctaataaaat tagagacgag gttttgctcg cggtaccact ctatttagct ttctaaaaag
     7081 ctcccttagt aatagccaat acaataatta taatgactat atttcctata acgtggaatt
     7141 actccgatta ttctaagatt taaatcttag aaaacagctc ctagacaagt tcagaactat
     7201 caactactaa atcacaccat cctttagctc tctgaaagtt tcattgttct tactacttct
     7261 attcatcact tttttaatca tttaaatttt ctaaatattt tgatttaata gttattatat
     7321 acacattaaa atgtattgtc aacagaaaaa ataattatct caatttttta tttttgataa
     7381 gcaattctat aaaacatgct aactattgaa aacagtatga tattatgcct taaacttttt
     7441 catcttttca tctatgatat tcaataattt tttttcatct tccaaactca atgcccttaa
     7501 tctaatttta taattagatt cgtcagtgta tatatttaat atatttttta ctacttctat
     7561 tttttctatt atcttataat taaacttttg actttgttta gattttatac tgaatataca
     7621 ttgattattt attaatattg aatgattatc gagagtaata tatacttttc cctcatattt
     7681 atttgaaaaa tcacgacctt gtttaaatag aaaaactgct gttattatac ataaaatata
     7741 taatattgtc gttgaatata taaaaattgt agctaaaatt ataagtgcta aaaccatata
     7801 tatagtcatt ccttttttaa aataaccatt gtcataataa ttcatataga taaacttatt
     7861 tttactcaaa ttttttcact cccaagattc taaaaattta tatcaaaaaa ttctataatt
     7921 tcatcttcat gataatttat gactaattca tctggaaaat ctactgcttc taaaactttt
     7981 tctgcatttt caaattctcc tatagaataa catatatgag agtcagtacc aagaattact
     8041 cttgcaccat atgttttaca caatgtcaac atatgactta cattttccca agtacccgtt
     8101 ctatgagagt ttgaacttaa tgatgaatta tttatttcta aaaggatatt tttatcttta
     8161 gcttttttta ctataggttc ataatctaaa ggatacctac tgtcatctgg atgtccaatt
     8221 atttttacct taggtttatc cataactttt aaaatagcat ttgtattttc ttcttttgta
     8281 ccagaagcta tacaaggtct atgcaaactt gcgattatat aatccaaatg ttgcaacata
     8341 tcttcttgaa catctaaatt accactataa tccattatat ttccttctat tcccctaaga
     8401 atctttacac cttgcacttc acgtggaagc aaatgcaaat tataaaaata gaatggatgt
     8461 ggtcctcctg gcatattagg tccgtggtct gatattccta agtattttat attcttctta
     8521 ctcgcctctt cgacattttc cttgaaagta ctatgtgcat gtccacttat tagagtgtga
     8581 caatgtacat ccataataga ctttttcatt aaatttcctc ctaatatttt acataaattc
     8641 gtgaaaatag ctaaagggct atttcaaaac taaagctgtc ataatagaca gtgtaacgtt
     8701 ttaaaacagc cccattttca attattttac acttctaaat ctttaaattt atctttaaat
     8761 aattctccaa tacttcctaa agattcctct acttctaggt attctgttat atcctcttct
     8821 ggctctctag ttgcttcttt tattgaaacc aacattcttt tagtctttgg tttaaaatca
     8881 agaatcttaa ctttaacctc atctccaata ttaacaacat tagtaacttt agccactcta
     8941 gtatcactca attcagatat tggtaaatac gcatctacac cttctttaat ttgaacaaaa
     9001 gccccttttt ctattattct aagaacttta gcattgacaa catcatcaat ttgtacttct
     9061 tttgctatta aatcccaagg gtcattattt atgtctttta atgccaaggc aattttttta
     9121 gtctctttat ttacatccaa cacataaact tctacttctt gtccctctga aacaacatct
     9181 tcaacacttt caactcttgt ccaagctaaa ttatttatat gtgctaatcc ttcaatccca
     9241 ccaatatcca caaatgcacc ataaggcatt atctttgtca ccttaccatc tcttttttgt
     9301 ccaacttcaa gagaattaaa taagtcttct ttagctgctt tgatacgagc tttttcttct
     9361 tctctttctt gcttaattct tgctctttca gcttcttttt ctgccttaat ttgagctctt
     9421 ctttcttctc tctctttatt tatacgctct tgtaatacat ctctatgaga tgctacaagt
     9481 ctattttttc taacatccaa ttcttttata taaacttcta agttaagacc aacaaattta
     9541 gatgtatctg taataaattt tgtatcaagt tgagaaattg gtataaaaaa tgtatatgta
     9601 ttgtaattag caaatacacc tttatctata ttcttttcaa catttacagt tattattcta
     9661 tgttcatcat aagccttttg taactcggca aaatcatttc ttttgtcaag ttgtaattta
     9721 gataaagtta ttgtaccatc tttttgagat acttttgtta ttacagcagt tatttcatca
     9781 cccatgtggt atatatcttc tatatattga tttttttcta tgttcaattc acttataggt
     9841 attattccat caaacccata gtctaatcct aattgtactt catcatttct cactgcagtt
     9901 atttttccag ttgtcaattc tccaactttc actttgctga atacttgttc ttgctggtca
     9961 agtaattctt gcattgttaa atcattttcc attataaaca tcctttcctc ttattgatta
    10021 tcatatctgt aaatattata ccattaatat tgcaaatact tacatttttc ttactataat
    10081 ttttaaaata aattcaactt catatattta tacattatag aaaatatctt attaaattaa
    10141 aatacaaatt ctaattttta tctaataaaa tattttcata aaaaatttat attgtatgtc
    10201 ttattctttt attgctttag gttttgatag aaaacattta taaaatataa agaaagaaat
    10261 tgctgttata gtagcagctg ttatatctgc aactggctct gctaaaatta ctgcaaaaag
    10321 tttttcatta aagaatgttg ggagtataaa tattaaaggt attaaaagta caatctttct
    10381 aagtagagct aaaaccaaag atattgttgc ttttccaagt gctaaaaatg tctgttgaca
    10441 agctatttga atcccaaaca taaaagcacc agcaaaatat atttttatac tccaactagt
    10501 catactaagt aactgcggat tcttattaaa tatactaaca aaaaatgcag gaaatatcat
    10561 taataaaagc cataaaatag tagaatatgt aaaacatgac aataaacaca acttaaatgt
    10621 cttttttact ctatcaagtt gacctgaacc ataattataa cttattattg gttgtgctcc
    10681 ttgtgtaacc cccatattag gaagcataag aatttgcatt atactgctca ttatggccat
    10741 tgaacctact gctaaatctc ctccatacat ttgtaattta ctatttaagg ctataagtac
    10801 taaactttct gtagattgca ttataaatgg agagattccc aagccaagca ctggtaagat
    10861 gatacttgct tttggtatca tatacttctt ttttatttta agtatacttt tctttccaaa
    10921 gagaaacata agtacccaaa tagcagaaac gccttgtgca attatagtag ctaatgcagc
    10981 tccttttaca cccatattaa agccaaatat aaaaatcggg tcaagtatta tgtttattaa
    11041 agcacctata gcaactgtca tcattccagt tgtagcaaac ccttgggtat ttataaaagt
    11101 attcataccc attgaaatct gaacaaacac tgtacctatt aaataaatat ttaaatagtc
    11161 cattgaatat ctaattgtag attcacttgc tccaaacatc caaagtaaag gctcttttcc
    11221 aatcttaaaa cctatagtca aaagtattgc taaaatcacc agtacagaaa aactgttact
    11281 cattattttc tctgcctcat cattgttttg ctcacccatt tttatagcag ctaatggacc
    11341 tcctcccata ccgattaaat aactacatgc agttattata attattattg gaaaggccac
    11401 tccaacacca gccatagcaa cttctccatt ttccattcta ccaataaaaa tcctatcgac
    11461 tatgttgtat aaaacattta caatttgtgc aataatagca ggtgtagcaa gtttaaataa
    11521 taatttaccc acactttcac tgcctaagtt agtgtttgaa ttttccattt taaaacctcc
    11581 tcaatccaat aattaaaatg tatcactaaa attttattct atataaaaat ttcattttat
    11641 cagcagacaa atttagagta ctttccctac aagtaatact atactatatt tcttttgcca
    11701 tagtaaacat tttagaacta actgaattta aatactttat ctcatttttt atttattatt
    11761 aaaaattttt cacatgtact cataaaaaaa ctatccaagt atattactta gatagtttta
    11821 tattatatgt aaagaaagag ctgaaactat aacccctgat aacaaattgc caagaaatac
    11881 tcccataaaa gcatctttta ttctcatttt taatatggaa gctatagcag atgcagtcca
    11941 tgttcctgta gttggcagtg gtatacctac aaatagtatt ataccaatta tcgaaacact
    12001 ttttaatttc ttcattcttg agtttatttt tctatcaatt acatcagcaa tccctttaaa
    12061 tagtttcttc cctcttaaaa attgtaatac atgtctgaat gtcaatatca agggaatcga
    12121 taccaatgta gaacctatta cactaaatac ataaacccat ataggattta agcccattgc
    12181 aatacctata ggaatggctc ccctcaattc tgttacagga accatagata aaattaatat
    12241 gtgtaaatat cccaaactat tccctcctat tctaagtgac attaagttat gaatttattt
    12301 gctctataac ctcaccatcc tttttactaa ctaaaaatgc atttttagtc aatgaaagca
    12361 ttggtaaatc actcttagag tctgaatatg catatgaatt ttcataatca atctctatcc
    12421 caagtttacc taatacagcc tttattcttt ttactttttc aattccctta cagttttctc
    12481 caatgaattg atttttatat cttgaatttt cataaaaaaa ctccgtgcct ataacctcgt
    12541 ctgcaagacc ataatactta aaatatttca tatatgcata tggagatgca gttatcataa
    12601 ttataacatt atcttcttct ttatttttgt aaatgacctt tttcatagat tcgttaattt
    12661 ttttcattat gcaatcatca aaaaactttt ttaaatcttc ttcactaaaa tctactattg
    12721 gataaaagat tgcctctttt gccttcttca agggtatcat tctaattaaa tacataaata
    12781 gaataaaaat aatgtatggc aactttataa tagttttaaa ggttttattt tttaaagagt
    12841 aaataaaaaa atctatcatg ctatcagtat ttataacagt ataatctaca tcaagtaata
    12901 atacactttt tttcataagt atttccccat cctatcacta aaaatatcac taaaaaatca
    12961 atattattaa acatgtaatt atccataaga ttacgtttat ttttaaagca ttatctttta
    13021 ggacaatatc agtaggatta ttttcatttg tagtgttaat tatataatta tatctaagta
    13081 caccataaac tacaaatatt gttgtaaata tcatatgtgg cttttctgga ttacttgtag
    13141 aatacaatgc ataacataca attgtagaac ttaatataac tatcatcatt tgatttagat
    13201 tttctatgtc ataatcttcc aatatttttc tatgttcaac tgcatcatct cttagagttt
    13261 ctatttcttt tttacgtttt ccaagagcta agtacagaga taagaaaaat gtacataaaa
    13321 ttatccaatt tgataaacta acacttatgg ctacacatcc tgcataaacc ctaagtataa
    13381 aaccaagaga tattgaaaac acatctaata gtattatatt ctttagttta agagaatata
    13441 atatattgtt tatcaaatag agactaagaa ttatagaaag attaaaacta acaactgttg
    13501 ataaacagac tgaaattaaa gctaatacta caaatagtat attagcactt tttttgctta
    13561 ttcttccact tgccactggt ctattacatt ttttaggatg ttttttatct ttatccatgt
    13621 ctatagcatc attcagtgca tatactgatg atgacattag gcaaaaacac acaaacgcaa
    13681 taaacgtatt taaaaataaa tttatattta gtatgttgtt tgaaaaaatt atagctgaaa
    13741 atacaaagaa attctttata tattgcttta ttctcattaa ctttatataa tctgaaattt
    13801 tagtaagaag ccttatactt gtattggtct gtttcataaa cttactaccc tttcaatatt
    13861 attttttaaa caggatatga ttttatccct atgtttaaaa tttctataaa tccattgaca
    13921 ttactgatta ctatagtaac caataacagc gatagaaata tattatacat attcttttca
    13981 ttttttctaa gcgctttcgt aaagtaagcc aataaaatta taactgcaaa actaaaattt
    14041 atagccataa tacttgaatt gactagatta tatcctacta taccatgtaa agttagattg
    14101 aatataatta ttcccataca tagcttagga actctttttt ctgaattttc aataactgat
    14161 aaaacacaaa aacataaagc taataatgta agaattactg gtattgtagc aacttctcca
    14221 ttttgcaaaa ataacccttt tttaatactt gctccaggaa aataaaaaac cgaatacaat
    14281 aatctctcta taatcattgc aatcttttcc aaaattggtt ctccacttat aaatttcgta
    14341 tcatactgta ttacatttcc aaggttcata aaactctcat aagacttcgt tgaaactaca
    14401 caaatatatg ccattaggat aaatgtaatt aaatgtttta acatttttcc tatttttaat
    14461 ttaaactcaa atatcatatt aaaaaaatac aaatatatat tactaatagt tattccaaat
    14521 agaggaatag ctgctaattc tactaaataa gaattttttc ctttcatctt atttgcaata
    14581 actatgaaaa atattaatga aaattggcta tatataaatc tctctacatt taaagtcata
    14641 aataactgtg gaaaagaaaa tatcattatc atagtaagta aaattaaagt taatctctgc
    14701 atttttatct ttttaatatg attaaagact aaagttattg acatagcact agttattatt
    14761 tgtagacaaa ttagtccaaa cccataggca ctattaaaat ctgttgtccc aggatttgct
    14821 attgaagtac aaaataggta tattggatat gcaaaaattg atataattgc tgaaaataat
    14881 atgtgcttac tattgtcttg acttatagca aatacattta aattgaataa tacccctgta
    14941 tctgtatcta acaatacatc ataagtattg tttaaatcat aaaatatagt agtcttagaa
    15001 aaaaatatct tagttattat taagtaagtt attacaacta atataaacaa aaacatctcg
    15061 tttttatatt ttaatatttt actcatcaat atatcaccat ccattcatta tataggattt
    15121 gctgacacct acaatttatt ccttatattt aatagccatc ttcataatgt tcttacttgt
    15181 tttattgtaa ttgaataact ctttatttac aaccacaata tttactttat tgatgttata
    15241 atcagtcaag tattgtttat ataacataga ttagtgttgt ataaaatgag aatttgtaag
    15301 caatattaat gtaaaatatt tgaaaaactt tatataaaaa tatacaatgt tacttatgga
    15361 attaaactat aacaaattaa agcataattt aaggagacaa aattataatc tgtctcctta
    15421 aatattaaaa ctatatttta aaacattact aaatactata caaatttcaa atatagtata
    15481 aaattaatta gactttaaca ctattagctc catcttcttc ccatttttta atttctttta
    15541 atctatctat tataggtaaa tgctgagtac attcaacttc acattttcca caagatatac
    15601 attctttagc ttttgcctta ctattcattg tgtaattcca atgtcctaaa ccataaacta
    15661 actttgtcat ttcttcatca ctctttttaa acatctgctt ttcattataa aaaagcatat
    15721 aggctggggt attaatacct tttggacata ctttacaata accacaacct gtacatattt
    15781 cgttcatatt cttatttaat ctagtctcaa tatcatgtat atcctcatct gaataaattc
    15841 tattttcgtc tgcaatttta catgcatcat ctatatcttg ttttttatta aaccctatca
    15901 aagatatact tatttgtgaa attcctatgt tgaatcttaa agctgattct atagtacttt
    15961 cgccatcttt tgatagaaaa gaaagttctt tattatactt tggaatagtt ccaccactta
    16021 atggattcat tgccacaaca ccatatccat tatcaacagc atatttggca ccttttagcc
    16081 tatatggaaa gtttaatata tttattccca tagttacacc ttcaaactta ttttcactta
    16141 gaatatctat aacctcatct cctggttgat gagatgaaaa tactatatgg tctatcaatc
    16201 cttcttcttt acatttcaat aatccttcat attgacctcc aggtctcatt gctagttcgt
    16261 aatgttccat ctttctaata ttccaaacat gataaaaatt tattttagat acgcctaatc
    16321 gttctattga tttttttaca gcctctatag ctttttctga tgtatcacat gcttttggct
    16381 tttctttagt tgatacataa aaatcggtct taccttcctt tatcatttgt ctaaaggcta
    16441 gtccaaatat atcttcactt ctgtcatcac aataccctgg tgctgtatca aagtaattaa
    16501 tacctttttc atacgcatat ttgactaaat cagcattttc ttgattactt ttttctaaat
    16561 caaaccttaa tcctccatag ccaactactg aaaccatttt ccctgtcttt ccatattcaa
    16621 cgtatctcat tgtaaattcc tccttagata tattaagact taatttcttt ataaaaaata
    16681 ttat
//
LOCUS       DACTZW010000089        16634 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.089, whole genome shotgun sequence.
ACCESSION   DACTZW010000089 DACTZW010000000
VERSION     DACTZW010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16634
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.089"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            185..2044
                     /locus_tag="JAM15_15555"
     CDS             185..2044
                     /locus_tag="JAM15_15555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HAT6799667.1"
                     /translation="MKRFLRRIILVLFILLIFISFISIKLIHNVGDYGKLINYVGIVR
                     GASQRLTKLEMNHQPNDELIEYIDEILQELITGHGDYGLVITDCNEYNEDLLLLEKKW
                     EDLNIEIKKVRMKEQNNQLLSISEEFFSLANDTVFKIENFSKEKSNYLMTLIIIISII
                     GILACIILILQYSKKMIRLEKLNVDLKNIAYKDELTGVNTIEKFKLDANQNICMHKDK
                     KFAVFYIDFENFKYINDIFGYDYGDMILKRYANLMMNDIGKYEIFAREIADRFVALRC
                     YVDKEDLVVRQRDVDNELINITNEIKNKHSITVVSGICCIEDVNEKLSIDGLINRANF
                     AQKTIKNKPGTNYAFYNDSIRKKMIEENTIKSRIHEAIEKREFIVYLQPKVNLHSQKI
                     NCAEALVRWLTPDKGIISPAIFIPVLEKNFFIALVDKYVFEEVCKWIRKRLDENKPFV
                     QISVNVSRIQFYNTKFVETYSNIQNKYRIPKNTIEIEFTESVAFENQKHLLEIIHDLH
                     ENGFTCSLDDFGKGYSSLSVLKDLPFDVLKLDSMFFKASLDKDKEKIVIKNIVYMLKE
                     LNITTVAEGIECKEQVEFLRDIGCDLVQGFVFYKPMPILEFEEILDKEFVYNS"
     gene            complement(2336..2935)
                     /locus_tag="JAM15_15560"
     CDS             complement(2336..2935)
                     /locus_tag="JAM15_15560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tellurium resistance"
                     /protein_id="HAT6799668.1"
                     /translation="MAIELKKGQKINLTKKENSDLGEILVNLNWNQKVQKKGFFGSLR
                     SSNIDLDLGCLFEMKNGVKGAVQALGNAFGSLDNPPFAQLDGDDRTGSNAQGENLRIN
                     GNKIKDIKRILIYAFIYEGVANWSEADGIVTIKQKQDSDLVVKLDEHKNGYNMCSIAL
                     IENVNDETFSVEKVVKYFKGHREMDTEFHWGLKWVAGRK"
     gene            complement(3038..3835)
                     /locus_tag="JAM15_15565"
     CDS             complement(3038..3835)
                     /locus_tag="JAM15_15565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HAT6799669.1"
                     /translation="MKFKKLLCLLLCLVLTLAVVGCSKAKDDKKIVVGATLVPGGELL
                     EELKPLIKEKGYTLEVKNFDDYILPNEALNNGEIDANLFQHEPYLKEAVKAKGYKIMA
                     GKKLYVCPAILYSYKIKSVDEFKKGDTIAISNNPSSCSKNLRYLESIGLLTLPKGDGL
                     VSPKDIIENPKGIQFKELDIAQIPSSLPDVTAAFIDTTYAVPAGLDAKKNGIYTAPIN
                     DEYANLLAFRTEDKDSEKIKVLQDVLTSDKARSLIEEKYKGIVIPTF"
     regulatory      complement(3948..4053)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(4145..5131)
                     /locus_tag="JAM15_15570"
     CDS             complement(4145..5131)
                     /locus_tag="JAM15_15570"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HAT6799670.1"
                     /translation="MLLIYNEKTNPYFNLAMEEYLLKNFDEDLFILWRNEPSIIVGKN
                     QNTLSEINLEYIKEYSIPVVRRQSGGGAVFHDLGNINFTFIACNNNNFSDFRRFTQPI
                     IDLLKTLDVNAEFSGRNDLLIDGKKFSGNAQYNYKNKVMHHGTLLFSSEINDLSKALK
                     VKPIKFEGKGIKSVKSRVTNISEHLHSKMDILEFKDAIMDYLSKTNTDNTNYCLNEHD
                     IKQIEKLTKSKYETWDWNFGNSPKYTLSNELKYSGGNVEFNLNVDKGIITSIKFFGDF
                     FGKCDVAFVENILIGIRHEENALRNTLDSIEINDYFLGADTDILVSGILGVK"
     gene            5615..7345
                     /locus_tag="JAM15_15575"
     CDS             5615..7345
                     /locus_tag="JAM15_15575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC family protein"
                     /protein_id="HAT6799671.1"
                     /translation="MRNKKINIIFLTTIMFIMSTVMVFAEEDIDTIALANAEKFGILT
                     LIPPLVAIILAFITKNVIISLLIGILSGSFIIKASGINVFATFIQAFLDLVDRALVSL
                     ADPWNAGIILQVLAIGGVINLVAKMGGAKAIAEALAKRAKSAKGTQLITWFLGLLVFF
                     DDYANSLIVGPMMRPVADKMKISREKLAFIIDATAAPVAGLAIISTWIGLEVGLIHDA
                     FESISIDVDAFGIFLNTIPFRFYNILILAFIVISALLLKEFGPMRKAEIKSRSRKISI
                     DLDEGVEELDDLAPKNGVKLSVWNAIIPIGTLIIVALASFYYSGYTSIMGGDDKALIQ
                     LFTNSPYSFEAIKEAFSASDASRALFQSALVASLVAIIMAVVKKIFTISEAIDVWIDG
                     MKSLVITGVILILAWSLSSVIKELGTAKFLIHLLSGSLPPFLLPSLIFGLGAIISFAT
                     GTAYGTMGILMPLAIPLAYSLNPDMSYVIVSTSAVLTGAIFGDHCSPISDTTILSSMG
                     AGCNHIDHVNTQMPYAIFTAVITIVFGYIPAGLGLPIYIVLPVAIAAIFVGIQIIGKK
                     VDEAEIELVE"
     gene            7455..7535
                     /locus_tag="JAM15_15580"
     tRNA            7455..7535
                     /locus_tag="JAM15_15580"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7489..7491,aa:Leu,seq:tag)
     gene            7870..8385
                     /locus_tag="JAM15_15585"
     CDS             7870..8385
                     /locus_tag="JAM15_15585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HXXEE domain-containing protein"
                     /protein_id="HAT6799672.1"
                     /translation="MEKYIWLFPLLFIFHDMEEIIGFGIWLKKNKSMLDKKYPFISKV
                     YENYSTEGMAFAVFEEFILCIIFCILTVITENQYVYLLWLGSFIAYTLHLVIHIGQSI
                     IIRKYIPSLITSIICLPISIWCISKSIYIVDCEMSTTILYSIIGIIIVALNLKFAQSL
                     IGKFTKWMSNI"
     regulatory      8877..8981
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            9191..11665
                     /locus_tag="JAM15_15590"
     CDS             9191..11665
                     /locus_tag="JAM15_15590"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPA"
                     /protein_id="HAT6799673.1"
                     /translation="MNELKRVSLYNIHKELGAKLVEFAGWEMPLEYEGINKEHEKVRK
                     SAGIFDVSHMGEVQIKGAESEKFIQNLVTNNISTLKINDIIYTPMCYENGGVVDDLLI
                     YKFGEEDYLLVINAGNIDKDVAWIIKQSEGYNVDIKNISSEVSQLAIQGPKAEEILQK
                     ITDIDLNSIKFYKSIPSTKVCGCPCLVSRTGYTGEDGFEIYCKNKYVEIIWNEVLKVG
                     GEDICPAGLGCRDTLRFEAALPLYGHEINEHISPIEGGLSIFVKTNKESFIGKSILSK
                     EKESGAKRKLVGFEMQGKGMPRNGYDIRIGDKTVGFVTTGCASPTTGKILGMGIIDSE
                     YAKVGNEIGIAIRKKVVPAVIVKKPFYKKQYKKDNIILNKENKFSYIPATSEDKSKML
                     KVVGLNSVDELFSDIPEEVKLKRDLNLEIGKSELEVSKIVKRLSEENLSLEDLTCFLG
                     AGAYDHYIPSIIKHITSRSEFYTAYTPYQAEISQGTLQVVFEFQSMIAEITGMEIANA
                     SMYDGATAAIEACIMAMNQTRKSKIVVSKTIHPETLSVLRTYLQYKDCEIVEIDFCNE
                     YGTTDIEKLKASVDKDTACVLIQTPNFFGIIEEMEEIEKITHENKAMLIMSVDPISLG
                     VLKTPGEIGADIVVGEAQSLGNPLNFGGPYVGFLASKSKYTRKMPGRIVGQSLDVEGK
                     IAYVLTLQTREQHVRREKATSNICSNQALNALVASIYMATMGKEGFKEVGMQSMKKAH
                     YTYNKLVQTGKYKPIFKGKFFKEFAVQGNLNIETINDKLLEENILGGYNLEYNYPELK
                     NSTLLCVTEKRSKEEIDKLVGIMEGL"
     gene            11665..13122
                     /locus_tag="JAM15_15595"
     CDS             11665..13122
                     /locus_tag="JAM15_15595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007060573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine dehydrogenase subunit 2"
                     /protein_id="HAT6799674.1"
                     /translation="MKEYNSLLIDISKKGRKAYSLPKLDIDDIKIEDMIDPDMARQSE
                     LNLPEVGELELVRHYTLLSNKNFGVDTGFYPLGSCTMKYNPKINEDMAALPNFTGMHP
                     YQSSDTAQGSLSLMYDLSRRLAEITGMDEVTLQPSAGSHGEFTGLMIIKAYHENRDDH
                     KRTKVIIPDSAHGTNPASAAMANFDVIQIASDKNGAVDINALKEVLNDEVAALMLTNP
                     STLGLFEKNIKEIATLVHEAGGLLYYDGANMNAIMGITRPGDMGFDVVHLNLHKTFST
                     PHGGGGPGAGPVGVKKELVPFLPIPVIERKEDKYVLNYDREKSIGKIKNFYGNFGVLV
                     RAYTYILTMGRDGLKEASEMAVLNANYIKESIKDDYILPIDTLCKHEFVLGGLPRGEA
                     NIKTIDIAKRLLDYGYHPPTMYFPLIINEALMIEPTESESIETVDSFIEAMKSVAKEA
                     KEEPELLKTAPHNTLVKRVDDARAVKKPILTWSQR"
     gene            13545..15902
                     /locus_tag="JAM15_15600"
     CDS             13545..15902
                     /locus_tag="JAM15_15600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HAT6799675.1"
                     /translation="MDKVNLERYSCDINVGLNKNQLQSRIDDNLINAFDNGKTKTYKQ
                     IFKDNIFTLFNLINIVLVCLLVSVGSFKNTLFIFIAVINTIIGVIQEIRAKRLLDNLS
                     VIVSNKVSVIREKEKKEIDVQELVLDDIMILKTGNQICADSKVLNGKLEVNESLVTGE
                     SDIIIKNKGDFLYSGSFVVSGEAFVRVENIGKDNYANKIANDAKISKKHNSQLRNSLN
                     AILKIVGIIIIPLGIILFAKQHFGNGDSIATSVVGTVAAVNGMIPEGLTLLTSIALAV
                     GTIKLASHKTLVQELYCVETLARVDTLCLDKTGTITEGKMQVDDIVMLEEVDINEIMG
                     NICNSLKDDNATLNAIRDKYNVLDTYKAKNLIPFSSERKYSGVTFENKGTYLLGAFEF
                     IFKEKNKKLRIEVERYSKKGNRVIVLAHSDSYMEDDNIPEDIKPLAFILILDKIRDEA
                     KETLEFFYNEGVDIKIISGDNPITVSEVARKAGLKTASNFIDATTLKNDSDIYKAVDK
                     YSVFGRVSPQQKKQMILALKKQNHTVAMTGDGVNDVLALKEADCSIAMASGSDVTKNV
                     SNLVLLDSNFASMPKVVMEGRKVINNIQRASSLFLVKTIFSFFLSLLTLFFFSRQYPF
                     VPIQLSLIGAVTVGIPSFFLALEANKSRISGNFLLNILKNALPGALCVTVNVIIVYNI
                     VEYLGYSSSVFSTMCAILTGVCGLLILRQQCLPFNKERLFLIVSMTIAFVIGILFLGG
                     LFSFVALSRELILITMALAILMPIMIKVMLFVLDEILETIVPDLN"
     gene            complement(15988..16305)
                     /locus_tag="JAM15_15605"
     CDS             complement(15988..16305)
                     /locus_tag="JAM15_15605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015393588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine/purine nucleoside phosphorylase"
                     /protein_id="HAT6799676.1"
                     /translation="MSEFKNVTAVKKANVYFDGKVSSRVIILPNGERKTLGLMLPGEY
                     TFSTREEEIMEMLAGSMDVKLPGSNEFVTYKEGQKFNVPSDSSFDLKVNEVVDYCCSY
                     IAD"
BASE COUNT         6290 a         1932 c         2717 g         5695 t
ORIGIN      
        1 ttgtatatat agaggactct aaagatgaac tatataaaac aaggtttata tattctatta
       61 tatattctat tatatattct aatagtatag aaaattttat tgtaaacgca tgtatattat
      121 tagaaaaaat agtttgaagg tattcaataa acataaaaaa caatataggg gataaaggtg
      181 ttttatgaag agatttttga ggagaattat cttagtttta tttattttgt tgatttttat
      241 aagttttatt tctattaaat taattcataa tgttggagat tatggaaaat taattaatta
      301 tgttgggatt gttcgtggag ctagccaacg tctaactaaa ctagagatga atcatcaacc
      361 aaatgatgaa ttaatagaat atattgatga aatcctacag gagttgatta cagggcatgg
      421 agattatggt ttagtaatca ctgattgtaa tgaatacaat gaggacttac ttttattaga
      481 aaaaaagtgg gaagatttaa atattgaaat taaaaaagta agaatgaaag aacagaataa
      541 ccagttatta agtataagtg aagagttttt ttctcttgca aatgatacag tgtttaaaat
      601 agaaaacttt tctaaagaaa aaagtaatta cttaatgact ttaataataa ttatatctat
      661 tataggtata ttagcatgta tcatattgat tttacaatat agtaaaaaaa tgattagact
      721 ggaaaaatta aatgtagatt taaaaaatat tgcatataaa gatgaactaa caggagtaaa
      781 tactatagaa aaatttaaat tggatgcaaa tcaaaatatt tgtatgcata aggataagaa
      841 atttgctgta ttctatattg attttgaaaa ctttaaatac attaatgata tatttggata
      901 tgattatggt gacatgatac tgaaaagata tgctaatctt atgatgaatg acatagggaa
      961 atatgaaata tttgcaagag aaattgcaga tagatttgtt gcgttaagat gctatgtaga
     1021 taaggaagat ttagtagtaa gacaacgaga tgtagacaat gaactaatta atataacaaa
     1081 tgaaattaaa aataaacata gtattactgt tgttagtgga atttgttgta ttgaagatgt
     1141 aaatgaaaaa ttaagtatag atggtttaat aaatagagca aattttgcac aaaaaactat
     1201 taagaataaa ccaggtacta attatgcttt ttataatgac agtattcgta aaaaaatgat
     1261 tgaagaaaat actatcaaga gtagaataca tgaagctatt gaaaaaagag aatttatagt
     1321 ttatttacag cctaaagtta atttacatag tcaaaaaata aattgtgcag aagctttagt
     1381 tcgttggctt actccggata aaggtattat atctccagca atatttattc cagtacttga
     1441 gaagaatttt tttattgcct tagtagataa gtatgttttt gaggaggttt gtaaatggat
     1501 tagaaagagg ttagatgaaa ataaaccttt tgttcagata tcagttaatg tttcaagaat
     1561 acaattttat aacactaaat ttgtagaaac ttattccaat atacaaaata aatataggat
     1621 acctaaaaat actatagaaa ttgaatttac agagagtgtt gcttttgaga atcaaaaaca
     1681 tcttttggaa attatacatg atttgcatga aaatggattt acttgttctt tagatgattt
     1741 tggaaaaggt tattcgtctt taagtgtttt aaaagattta ccatttgatg ttttaaagct
     1801 tgactctatg tttttcaagg ctagtttaga taaagataaa gagaaaatag taataaaaaa
     1861 tattgtatat atgttaaaag agcttaatat cacaactgtt gctgagggca ttgaatgcaa
     1921 ggaacaagtt gaatttctta gggatattgg gtgtgattta gttcagggat ttgtatttta
     1981 taaaccaatg ccaatattag aatttgaaga aatattggat aaagagtttg tttataatag
     2041 ctaaaatgta ctttataaaa tatgaactaa ttaagtaaaa ttattttgta ctgaataaat
     2101 ttttacttta tttacagaat agtgattatt tacagaaaag ggcgaaaagt gtattccttt
     2161 aagtgtggga tggatagcac aaatagggga gaaaaaatat tggccatata agaatgcata
     2221 ataatataaa tatttgaaag gtcagcatta tataaaaatt aaaaagaaaa taaataattt
     2281 ttctataaaa aagagactat gagaaaagtt actcatagtc tcctaaataa tgtatttatt
     2341 ttcttcctgc aacccatttt aagccccaat gaaattcagt atccatttct ctatgacctt
     2401 tgaagtattt aactactttt tcaacactga atgtctcatc atttacattt tctatcaatg
     2461 ctattgaaca catattatag ccatttttat gttcatcaag tttgacaact aagtctgaat
     2521 cttgtttttg tttgattgtt acaattccat cagcttcaga ccagttagct acaccttcgt
     2581 atataaaagc ataaataagt attcttttta tatcttttat tttattacca tttattctta
     2641 aattttctcc ttgtgcatta cttcctgttc tgtcatctcc atctaattga gcaaaaggtg
     2701 gattgtctaa actaccaaaa gcatttccta atgcttgaac agcacctttt acaccatttt
     2761 tcatctcaaa taggcaaccc aaatctaaat ctatattact gcttcttaaa gagccaaaaa
     2821 aacccttttt ttgtactttt tgattccaat ttaaattaac taagatttca cctaaatcgc
     2881 tattttcctt ttttgtaagg tttatttttt gtcccttttt taattctata gccatagtaa
     2941 ttttcctcca caaacataga tttatttaaa tggtagcact taataagtca atattcaaca
     3001 agattagaat aataatatta aaactatact aaatatacta aaaagtagga atcacaatac
     3061 ctttgtattt ttcttcaatt aagcttcttg ctttatctga tgtaagaaca tcttgtagaa
     3121 ctttaatctt ttcactgtct ttatcttcag ttctaaatgc taaaagattt gcatactcgt
     3181 catttatagg agctgtataa attccgtttt tcttggcatc aagaccagca ggtacagcat
     3241 aagtagtatc tataaatgca gcagtaacat ctggaagaga agatggaatt tgagcaatat
     3301 ctaactcttt gaattgtatt ccctttggat tttctattat gtccttagga ctaactaatc
     3361 catccccttt aggtaacgtt aaaagtccaa tactttcaag gtatctaagg ttcttagagc
     3421 aagaagatgg gttattgctt attgcaattg tatctccttt tttaaattca tcaacagatt
     3481 ttatcttata agagtaaagt attgctgggc atacatatag ttttttacca gccattattt
     3541 tgtaaccttt ggccttaaca gcttctttta gataaggttc atgttgaaat agatttgcat
     3601 caatttcacc attatttaaa gcttcgtttg gaagtatgta atcatcaaag tttttaactt
     3661 ctaaagtata tcctttttct ttaataagtg gttttaattc ttctaataac tctcctcctg
     3721 gaactaaagt agcaccaaca acaatttttt tatcatcttt agctttagaa catccaacca
     3781 cagctaaagt taatactaga cataataaca aacataataa ttttttgaat ttcatataaa
     3841 ttccctcctg aatataattg attagttaaa aataaaatac cattctttat cacactgcaa
     3901 aataaaaata agcctgagtt taaactcagg ctttaaaagc taatttagac tcatctttca
     3961 gtataatact gcaggattta gcaccaatgt atataaaaat atactggttg ctgggtttca
     4021 tagggccagt cccttcacca ctctggataa gaagtatcaa tttttaatta tgttataaat
     4081 attatcatga ttttttacgt ctgtaaacat aattttataa atattttaaa atctttaatg
     4141 tattttattt aacacctaaa attccagaaa ctagaatatc agtatcagca cctaagaaat
     4201 agtcatttat ttcaatagaa tccagagtat ttctcaaagc attttcttca tgccttatac
     4261 caataagtat attttctaca aatgcaacat cacattttcc aaaaaaatct ccaaaaaatt
     4321 ttatactagt tattatgcct ttatcaacat tcaaattaaa ctcaacattt ccaccagaat
     4381 attttaattc atttgaaaga gtatattttg gtgaattacc aaaattccaa tcccaagttt
     4441 cgtattttga tttagtaagc ttttctattt gttttatatc atgctcattc aaacaataat
     4501 tagtattatc agtatttgtt ttagaaagat aatccattat agcatcttta aattctaata
     4561 tgtccatttt tgaatgtaaa tgttcactta tattggttac acgagatttt acagatttta
     4621 ttccttttcc ttcaaatttt ataggtttaa cctttaatgc ttttgagagg tcatttattt
     4681 cagatgaaaa taaaagagta ccatgatgca ttactttgtt tttgtagttg tattgagcat
     4741 ttccagaaaa tttcttgcca tctataagaa ggtcatttct tccagaaaat tcggcattga
     4801 catctagtgt tttaagtaaa tctattatgg gctgagtgaa tcttctgaaa tcactaaaat
     4861 tattattgtt acaagctata aatgtaaaat ttatatttcc caaatcatga aatacagctc
     4921 caccaccaga ctgtctccta acgacaggta tagaatattc ttttatatat tctaaattta
     4981 tttcagaaag tgtgttttgg ttttttccaa caattataga aggttcattc ctccataaaa
     5041 taaataagtc ttcatcaaaa ttttttagaa gatattcttc cattgctaaa ttaaaataag
     5101 ggtttgtttt ttcattataa attaataaca ttaaagtagt tcctccagag aattgataaa
     5161 atttttatta tgaatacaat taattttata attcgacaat aatataaaaa ctcctttaaa
     5221 ttagaaattt taaaaactac cttgcaaagt ttaaataaat aatatatact caaaatatgt
     5281 ttaataaaag tgaatagaag ggtagaggcg caataatcta tcagtactaa taaggagtta
     5341 agcacagaga gttattagga aaggagatat tgccgaagtt ttataatcga tgctttaaga
     5401 ttatattgct gggggtacat agaaaatatg tacaactgtc acaggtttat ttgtggtgag
     5461 ctatcattta aggaattata ttatatttat ttttactatt gttgatatat tgtaatgttt
     5521 aagccttgag tgtttaccac tcaaggcttt tttagtttta ttgtaacata ataccctgta
     5581 cagttcacaa aattaaaagg agagggagat ttatatgagg aacaaaaaaa ttaatattat
     5641 ttttctgacg acaatcatgt tcataatgtc aacagtaatg gtttttgcag aagaagatat
     5701 agacactatt gcactagcca atgcagaaaa atttgggatt ttaactttaa taccaccatt
     5761 agttgctata atacttgcat ttataactaa aaacgtaata atttctttac ttataggtat
     5821 tctttctggt agttttataa ttaaagctag tggtattaat gtttttgcga catttataca
     5881 ggcattttta gatttagtag atagagcttt agtatcttta gcagaccctt ggaatgcagg
     5941 gataatacta caggttttgg caattggagg agtaataaat cttgttgcta aaatgggagg
     6001 agctaaagct atagctgaag cacttgctaa aagagcaaag tcagcaaaag ggacacagct
     6061 tataacatgg tttttggggc ttttagtatt ctttgatgat tatgccaatt cactaatagt
     6121 aggtcctatg atgagacctg ttgcagataa aatgaaaata tcgagagaaa agctagcatt
     6181 tataatagat gccacagcag caccagttgc tggtttagct ataatatcta catggatagg
     6241 tcttgaggtt ggtttaatac atgatgcttt tgaaagtata agtatagatg tagatgcatt
     6301 tggtatattt ttaaatacaa taccatttag attttacaat atattaatat tagctttcat
     6361 tgtaatatca gcattattat taaaagaatt tggtccaatg agaaaagctg agataaaatc
     6421 tagaagtaga aaaattagta tagaccttga tgaaggcgta gaagagttgg atgatttagc
     6481 tccaaaaaat ggagtaaaat tgagtgtatg gaatgctata atcccaatag gaacattgat
     6541 aatagttgca ttagcatcat tttattatag tggatataca tctataatgg gaggagacga
     6601 taaggctctg atacaactat ttacaaattc tccatattct tttgaagcaa taaaagaagc
     6661 atttagtgca tctgatgcat ctagagcatt attccagtct gcacttgttg caagtttagt
     6721 tgctattata atggctgtag taaaaaagat ttttacaata tcagaagcaa ttgatgtttg
     6781 gatagatgga atgaaaagtt tagtaatcac tggtgtaata ttaatacttg catggtcatt
     6841 aagttcagta ataaaagagt taggtacagc taaattttta atacacctat tatcaggttc
     6901 actaccacca ttcttattac caagtttaat atttggttta ggagcaataa tatcttttgc
     6961 tactggaaca gcttatggaa caatgggtat acttatgcca cttgcaattc cattagcata
     7021 ctcattaaat cctgatatgt cttatgtaat agtaagtact agtgcagttt taacaggtgc
     7081 aatatttgga gaccattgtt ctccaatttc agatacaaca atactttctt caatgggagc
     7141 tggctgtaat catatagacc atgttaacac tcaaatgcca tatgctatat ttacagcagt
     7201 aatcactatt gtatttgggt atataccagc tggacttgga ttgccaatat atatagtatt
     7261 accagtggca atagctgcta tatttgtagg tattcaaata attggtaaga aagttgatga
     7321 agcggaaata gaacttgtag aataaagata taaataagtt tcacctttta ttatcactat
     7381 tttgttagtt tttagataat tttaaaaagt tattgaaaat aatggtgaaa tatagtaaaa
     7441 taaaagagtg ataagcggat gtggcggaat tggcagacgc actagactta ggatctagcg
     7501 ccattggcgt gggggttcga ctcccttcat ccgcacttta cagtacttaa ttgtactgaa
     7561 aaaaactggg gttgctggct ttcggagtgg gctatcccgt ttttattttt ttgtatatat
     7621 aatagattgg cactttagta taaggtgctt tttttatagg caaaaacagt acatttattt
     7681 ctgttttatt atcattcatc tattagaata tactttagtt aagaatgtgt taataagcag
     7741 tgttcacatt cttgataaaa tgtggaataa tatgtatttt tactaagaca gaaatgaaat
     7801 aactaaacca ttaaataata ttataagatt atgaataagt agataaatca aattttgtag
     7861 gaggatatta tggaaaaata tatatggttg tttccattac tttttatttt tcatgatatg
     7921 gaagagataa taggttttgg aatatggctt aaaaaaaata aatcaatgct tgataagaag
     7981 tatccattta tcagtaaagt ttatgaaaat tatagtactg aaggcatggc atttgctgtg
     8041 tttgaagaat ttattttatg cattattttc tgtatactta cagttataac agagaatcag
     8101 tatgtatatc tactatggtt aggtagtttt atagcatata ccttacattt ggtaattcat
     8161 atagggcagt caatcataat aagaaaatat ataccttcac ttattaccag tatcatatgc
     8221 ttaccaataa gcatttggtg tataagtaag agtatttata tagttgattg tgaaatgagt
     8281 acaacaattc tgtacagtat aattggcatt ataattgtag cattgaattt aaagtttgca
     8341 cagtcgctga ttggaaaatt tacaaagtgg atgtcaaaca tataaatttt agtttattgg
     8401 acagttcaag gaatcagaaa ttggaatttt atagtattaa tattttatag tattaatata
     8461 atgtataaaa ttttatagca atgtatttca taagtataaa gtgactagaa ttttaagaaa
     8521 tatacaaatt ctataaaaac taaataattt caagtatatt ttaaaaatct tatttttcac
     8581 aagtttaaaa ttgtaaacga tttcatcaag tctatgaata tacttttaac atgttatagt
     8641 aaatctcaat ataaatttac atttggttct ttgtgtgtta ttttaataat aaattaagtg
     8701 aaaatgttat tttacattaa tatataatat ctttgcataa gagtgaataa tataaaagag
     8761 aaataattga taataaaaac ttaacaaaaa aattaataca taaaaaaaaa taaatataat
     8821 gtgttgacat ttaattgaaa tattcataca ataaaattga aaataaatat ttccaaatga
     8881 gattagcgag agagtccttt atacgaaaag gcgccgaaga agaaatttaa gaaatgccaa
     8941 tttttagaga agctttcagg caaaaatatc gctaattgat gggactctgg agagacttaa
     9001 gttaagatac tataagtcac cgaagaagca aaataatatt aaattattaa atctttcagg
     9061 tatacaaaca gggatatata ggctaggatt attttccatg ctgatatatc ttttttttat
     9121 gaaaaagtac aggaaataat atcaaagtta cttaaataca gtaggtctaa ttttctaggg
     9181 agggttatat atgaatgaat tgaaaagagt atctttgtac aatatacaca aagagcttgg
     9241 agcaaaactt gttgaatttg ctggttggga aatgccttta gaatatgagg gtataaataa
     9301 agagcatgag aaggtcagaa aaagtgcagg tatatttgat gtatctcata tgggagaggt
     9361 acagataaag ggagcagagt cagaaaaatt tatacaaaac ctagttacaa ataatataag
     9421 cacattaaag ataaatgaca ttatatatac acctatgtgt tatgaaaatg gtggagtagt
     9481 tgatgattta ttaatatata aatttggtga agaagattat ttattagtaa taaatgcagg
     9541 taatatagat aaagatgtag catggataat aaaacaaagt gaaggataca atgtagatat
     9601 aaaaaatata tctagtgaag tgagtcaatt agcaattcaa ggacctaaag cagaagaaat
     9661 tcttcaaaaa atcacagata tagacttaaa ctcaataaaa ttttataagt caattccatc
     9721 aacaaaagta tgtggttgtc cttgtttagt ttcaagaaca ggatatactg gggaagatgg
     9781 gtttgagata tactgtaaaa ataaatatgt agaaataatt tggaatgaag ttctaaaggt
     9841 tggaggagaa gatatatgtc cagctggtct aggttgtagg gatactttga gatttgaagc
     9901 agctctacct ctatatggac atgaaataaa tgaacacata tctccaattg aaggtggttt
     9961 atctatcttt gtgaaaacaa ataaagaatc atttattggc aaatcaattt tatcaaaaga
    10021 aaaagaaagt ggagctaaaa gaaagttagt aggatttgaa atgcaaggta aaggaatgcc
    10081 tagaaatgga tatgatataa ggattggtga taaaacagtt ggatttgtaa caacaggatg
    10141 tgcatctcca acgacaggaa aaattttagg tatgggaatt atagattctg aatatgcaaa
    10201 agtaggaaat gaaataggta tagcaatcag aaaaaaagtt gttcctgctg tgatagttaa
    10261 gaaacctttt tataaaaaac aatataaaaa agataatatt atattaaaca aagaaaataa
    10321 attttcatat atacctgcta caagtgaaga taaatcaaaa atgttaaaag tagttggatt
    10381 aaattcagtt gatgaattat tttcagatat accagaagaa gtaaaattaa aaagagattt
    10441 aaatttggaa attggaaaat ctgaattaga ggtaagcaaa atagtaaaaa gattgtcaga
    10501 agaaaattta agtttagaag acttgacttg ttttcttggt gctggtgcat atgaccatta
    10561 tataccatca attataaaac atataacttc aagatctgaa ttttatacag catatacccc
    10621 atatcaagct gaaataagtc agggaacttt acaagtagtt tttgaatttc aatctatgat
    10681 tgcagaaatt acaggtatgg aaattgcaaa tgcatcaatg tatgatggag caactgctgc
    10741 aatagaagca tgtataatgg caatgaatca gactagaaaa agtaaaatag tagtgtcaaa
    10801 aactattcat cctgaaactc tgtcagtatt aagaacttac ttacaatata aagattgtga
    10861 gatagtagaa attgactttt gtaatgaata tgggactaca gatatagaaa aattaaaagc
    10921 ttctgtagac aaagatacag catgtgttct tatacaaact cctaatttct ttggaattat
    10981 tgaagaaatg gaagaaatag aaaagataac tcatgaaaat aaggctatgt taattatgag
    11041 tgtagaccca atatcattag gagttttaaa aacaccaggt gagataggtg cagatattgt
    11101 tgttggagaa gctcaatcac ttggaaaccc tcttaatttt ggaggtcctt atgtaggatt
    11161 tttagctagc aaatctaaat atactagaaa aatgccagga agaatagttg ggcaaagttt
    11221 agatgtagaa ggtaaaattg catatgtatt aactttacaa actagagaac agcatgtaag
    11281 aagagaaaaa gcaacttcta atatatgttc aaatcaagct ttaaatgctc ttgtagcttc
    11341 aatatatatg gctactatgg gtaaagaagg atttaaagag gttggtatgc agtctatgaa
    11401 aaaagcacat tatacctaca ataaacttgt acaaactgga aaatataagc caatatttaa
    11461 aggtaagttt ttcaaagaat ttgctgtaca aggaaatctt aatatagaaa ctataaatga
    11521 taaactctta gaagaaaata tattaggagg ttataattta gaatacaatt atccagaatt
    11581 aaaaaattca actttgcttt gtgtgactga gaaaagaagc aaagaggaaa tagataagtt
    11641 agttggaata atggagggat tataatgaaa gaatacaata gtttgttgat agatatatct
    11701 aaaaaaggta ggaaagcata ctcacttcca aagttagata tagatgatat aaaaatagaa
    11761 gatatgattg acccagatat ggcaagacaa agtgagttga atttgccaga agttggtgaa
    11821 ttagaattag ttagacatta tacattatta tcaaataaaa actttggagt tgatacaggt
    11881 ttttatcctt tgggttcttg tactatgaaa tataatccta aaataaatga agatatggca
    11941 gcacttccaa actttactgg aatgcatcca taccaatctt cggatacagc tcaaggttct
    12001 ctttctttga tgtatgattt atcaagaaga cttgcagaaa ttacaggtat ggatgaagtt
    12061 acactacaac cttcagcagg ttctcatggt gagtttacag ggcttatgat tataaaagca
    12121 tatcatgaaa atagagatga ccataagaga accaaagtga taattccaga ttctgcacat
    12181 ggaacaaatc cagcaagtgc agctatggca aactttgatg tgattcaaat agcatctgat
    12241 aaaaatggag ctgtagacat aaatgcatta aaagaggttt tgaatgatga agtagcagct
    12301 cttatgctta ctaatccaag tactcttggt ttatttgaaa aaaatataaa agaaatagct
    12361 actcttgtac atgaagcagg aggacttttg tactatgatg gtgcaaacat gaacgctatt
    12421 atggggataa caagacctgg agatatgggg tttgatgtgg ttcatcttaa tcttcataag
    12481 actttttcaa ctcctcatgg aggtggaggt ccaggagctg gtcctgttgg agttaaaaaa
    12541 gaattagtac cttttttacc aataccagta attgaaagaa aagaagataa gtatgtacta
    12601 aattatgata gagaaaaatc tattgggaaa attaaaaatt tctatggtaa ttttggagtt
    12661 cttgtaagag cttacacata tatactaact atgggaaggg atggacttaa agaggctagt
    12721 gaaatggcag ttttaaatgc taattatata aaggaaagta taaaagatga ttatattttg
    12781 ccaatagata ccttgtgtaa gcatgagttt gtattaggtg gattgccaag aggagaggcc
    12841 aatataaaaa ctatcgatat tgcaaaaaga ctactagatt atggatacca tcctccaaca
    12901 atgtactttc ctcttattat aaatgaggca cttatgatag aacctacaga aagtgagagt
    12961 atagagacag tagatagttt tatagaagct atgaaaagtg ttgctaaaga ggcaaaggaa
    13021 gaaccagaac tattgaaaac tgccccacat aatactttgg tcaaaagagt agatgatgca
    13081 agggcagtaa agaaacctat actaacatgg tcacaaagat aaatagttaa aaagtagaga
    13141 tttaaagtat aaagagaatt aaatttataa gaaaaagcta tctaacttaa tctagtttag
    13201 atagcttttt tgtatattag tatatatggt atttcctata taaagtttta aattatatta
    13261 gtgcttatat agaatattga tatgatgatt atgtatagat attaataaga attgttgaat
    13321 ttatcttgcc ttaactttat ttactctttt atattaagaa aaacttaact aaaatatagc
    13381 gaaattcata aaaatttagg aaatcttaag aattataata tttaaatctt tagatttata
    13441 ttttattata taaactatag aataataaaa taaaaaaatt gagaatttta taatatattt
    13501 gtagatttga gtataaaaaa gtgctaagtt gaaaggagta aaatatggat aaggttaatt
    13561 tagaaaggta tagttgtgat ataaatgttg gtttaaataa aaatcaactt caaagtagaa
    13621 tagatgataa tttaattaat gcatttgata atggaaaaac caaaacatat aaacaaattt
    13681 ttaaagacaa tatatttaca ctttttaatc tcataaatat tgttttagtc tgtttattag
    13741 tttcagttgg ttcttttaaa aataccttat ttatatttat tgctgtaatt aatactatta
    13801 taggagtaat acaagagata agagctaaaa gattattgga caatctatct gttatagttt
    13861 caaataaggt atctgtcata agagaaaaag agaaaaaaga gattgatgta caagaattag
    13921 tattagatga tattatgatt ttaaaaacag gtaatcaaat ttgtgcagat tcaaaagttt
    13981 taaatggaaa attagaggta aatgagtctt tggttacagg tgaatctgat attattataa
    14041 aaaataaagg cgatttttta tattctggaa gttttgtagt ttctggagaa gcttttgtaa
    14101 gagttgaaaa tataggaaaa gataactatg caaataagat agctaatgat gcaaagattt
    14161 ctaaaaaaca taattctcaa cttagaaatt cattaaatgc aatattaaaa attgtaggta
    14221 taataataat tcctctagga attatattgt ttgcaaaaca acattttgga aatggagatt
    14281 ctatagctac atctgtagta ggtacagtgg cagctgtaaa tggtatgata ccagagggat
    14341 taacattact tacgagcatt gctctagctg taggaactat aaaacttgct agtcataaaa
    14401 ctttagtgca agaactgtac tgtgtagaga ctcttgctag agttgataca ctatgtcttg
    14461 ataagacagg tacaattaca gaaggtaaaa tgcaagttga tgatatagta atgttggaag
    14521 aagtggatat taatgaaata atggggaata tatgtaattc tctcaaagat gataatgcaa
    14581 cactaaatgc aataagagat aagtataatg ttttagatac gtataaagct aagaatttaa
    14641 taccattttc ttcagaaaga aaatacagtg gggttacctt tgaaaataaa ggtacatatt
    14701 tattaggtgc atttgagttt atatttaagg aaaaaaataa aaaacttagg atagaagttg
    14761 aaagatattc taaaaaagga aacagagtaa tagttttagc tcatagtgat tcttatatgg
    14821 aagatgataa tattcctgaa gatataaagc cactagcttt tatattgata ttggataaaa
    14881 ttagagatga agctaaggaa actttagaat ttttttacaa tgaaggtgta gatataaaaa
    14941 ttatatctgg tgacaatcct ataacagtaa gtgaggtagc tagaaaagca ggtcttaaaa
    15001 cagctagtaa ttttattgat gcaacaacac ttaaaaatga tagtgatata tacaaagcag
    15061 ttgataaata cagtgttttt ggaagggtaa gcccacaaca gaaaaaacaa atgattttag
    15121 cattaaaaaa acaaaatcat acagtagcta tgactggaga tggtgtaaat gatgtgctag
    15181 cacttaaaga agcggattgt agcattgcca tggcatctgg aagtgatgtt actaagaatg
    15241 tgtctaattt agtcttatta gattcaaact ttgcatcaat gccaaaggtt gttatggagg
    15301 gaagaaaagt aattaataac attcaaagag catcttcttt gtttttagta aagacaattt
    15361 tttcattctt cttgtcgtta ttaacattat tcttcttcag tagacagtat ccatttgttc
    15421 ctatacaatt atcactcatt ggggctgtaa cagtgggtat accatcattc ttcttagctc
    15481 ttgaagcaaa caaaagtaga atttcaggaa attttttact caatatatta aaaaatgctt
    15541 taccaggagc actatgtgtg acagtaaatg taattattgt ttacaatata gttgaatatt
    15601 taggttatag ttcaagtgta ttttccacaa tgtgtgctat attaactggt gtatgtggtc
    15661 ttttaatatt aagacaacaa tgtttgccat ttaataaaga aagattattt ttaatagtaa
    15721 gtatgactat tgcatttgtt attgggattc tatttttagg tggattattc tcatttgtag
    15781 cattgagtag agaattaatt ctcataacta tggcattagc aatattaatg ccaattatga
    15841 taaaagttat gttatttgtc ttagatgaga tattagagac aattgttcca gatttaaatt
    15901 aattttaaaa tgatataaat aagagcagtt ttagttgaac tgctcttttt agatgtgttt
    15961 aattttatgt aagaatatgt atttttatta atcagctata tatgagcaac agtagtcaac
    16021 aacttcatta acctttaagt caaaacttga atcactagga acattaaatt tttgcccttc
    16081 tttataagtt acaaactcat tgcttccagg cagttttaca tccatacttc cagcaagcat
    16141 ctccattatt tcttcttctc tagtagaaaa agtgtattct cctggcaaca ttaatcctaa
    16201 agtttttctt tctccattag gcagtattat tactctgcta cttaccttac catcaaaata
    16261 aacgtttgcc ttctttactg cagtaacatt cttaaattca ctcattagat aaaacctcca
    16321 aaattatttg tacatatata ttatataaaa ataatgtaaa aaatgctata tatttacaaa
    16381 aaaatttagt atttattaaa aaaattaata agaataaaaa agagatgaaa ttgcttaaat
    16441 tgataaaaaa tataaaataa attgcaaagt aagcaagaaa agaataagtt gaagagttat
    16501 atattataaa tattaaaaat tttagtatta ataaaaaaga tattacatta atatgaaaat
    16561 ataggagatt agaagtgttt gattaaaaaa tagctacaca cacttgtgac tttagtcatg
    16621 agttagtagc taaa
//
LOCUS       DACTZW010000090        16292 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.090, whole genome shotgun sequence.
ACCESSION   DACTZW010000090 DACTZW010000000
VERSION     DACTZW010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16292
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.090"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(148..1029)
                     /locus_tag="JAM15_15610"
     CDS             complement(148..1029)
                     /locus_tag="JAM15_15610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HAT6799677.1"
                     /translation="MKKRLIIMILSVVLVLSSILTIFAYSNIKYNNNKLIYSNMIDKK
                     TQNSVKEILKENKINEKDIDTFIKAVNNYNKLQVKILQNNINISKSGYSSINAKQVPY
                     NLEKLQDNWVKKFPDYMDVNCRITAFRLFKDFINSNKKFTGDSIDLNVDLDTIMNNKD
                     AKFSTKDVEKFINFFSAIPAKDTDDTIKIAEQIKNEWKKRKISFKNNKNISIINGFLR
                     YPETKNVFIGHTGICIKTKNGILFLEKYGVTSPYQVTKFKNKEDVKNYMFNRLKMSEG
                     EIELPDPIIMENDKLMK"
     gene            1582..2094
                     /locus_tag="JAM15_15615"
     CDS             1582..2094
                     /locus_tag="JAM15_15615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799678.1"
                     /translation="MKVKKFKSGIVMALTVMAIGASLTNVSAMELNKSKEFETKYNEM
                     KRDFQEDYGKEDKFNITLDDEFTKEEVNGAKGIIKTTNKMNNEVVVLNYFDEMKSGIE
                     FELKPKAEKNAILRDEFQQGYGKEDKFKVVLDDEFTKEEVNGAKGIIKTTDKETGEVI
                     VYNYFDELEK"
     gene            complement(2732..3283)
                     /locus_tag="JAM15_15620"
                     /pseudo
     CDS             complement(2732..3283)
                     /locus_tag="JAM15_15620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418382.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
     gene            3491..3581
                     /locus_tag="JAM15_15625"
     tRNA            3491..3581
                     /locus_tag="JAM15_15625"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3525..3527,aa:Ser,seq:gct)
     gene            3669..4457
                     /locus_tag="JAM15_15630"
     CDS             3669..4457
                     /locus_tag="JAM15_15630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein"
                     /protein_id="HAT6799679.1"
                     /translation="MTTLIFFIVGIASLVVAFVIDGGHVGALFVFSSALVVFGGTIGA
                     VGASTPFPVFKKSIKIMLLAFKNKKPNNIENIIYFKEIATKARKEGLLSIDKEISEND
                     ELDPFIRKGLELMVDGVDAVTIRNILESQIQITSKRHKEGIAIFDSAGGYAPTLGIIG
                     TVMGLVHILGNLSSNPDALGPQISVAFLATLYGVGSANLIWLPIASKLKAINQQEVSE
                     RLLVIEAILSILEGDNSNLMTEKLKIFLNSKELIELEEIGGRAE"
     gene            4478..5218
                     /locus_tag="JAM15_15635"
     CDS             4478..5218
                     /locus_tag="JAM15_15635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HAT6799680.1"
                     /translation="MLYDEDEKEENNERWLLTYSDLITLLMIFFVIMYSMSNVDAEKY
                     KQLSQSLNSAFGGSSGVIEGGNSKIEPVVEPGSNDLDTLQNAKFKKVGEEIQKYLNEN
                     GMANSVSLRVQDRGLVISLKDTILFDTGKAVVKDNSRDKIIQIGKMLNEMNSYMRVEG
                     HTDNMSIKNSEFKSNWDLSVMRATNVVQLLIDNAGIAPDKLSAVGYGEFRPIAENSSE
                     EGRSKNRRVDIVLVDSKYDNVENVSKDK"
     gene            5396..5770
                     /locus_tag="JAM15_15640"
     CDS             5396..5770
                     /locus_tag="JAM15_15640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799681.1"
                     /translation="MGNKNKNTKYKDKTRERYNKKVENLNKEKLNKDNKQSKKVDKID
                     DIINKSSIVLCVLLVVFSLLYLFKLVQLNIIMILLVITVAIQQGLVSFGAFRNKNYVK
                     ALFSIFVIVCFLIAFKYVVNPV"
     gene            5862..7322
                     /locus_tag="JAM15_15645"
     CDS             5862..7322
                     /locus_tag="JAM15_15645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAT6799682.1"
                     /translation="MNRCKFAKLIITSMIVLLLTGCSLKKEDNYKLDPENPTSIQIWH
                     YYNGQQKMAFDKLVKEFNDTIGAEKGIIVEAFSQGNVVDLSEKVLDSANKKVGSEDVP
                     NIFAAYSDTAYEMDKLGLLVDMDKYISKEELNEYIDEYVEEGRINSKDEFKLFPIAKS
                     TEILMLNKTDWDKFAKATNSNINDIKTIEGLVETSKKYYEWTDSLTKEPNDGKAFFGR
                     DALANYIIIGSKQLGVEIFSVKDGKVTLNIEEKVMKKLWDNFYVPYINGYFASYGKFR
                     SDDAKTGDILALVGSSSGAAYFPDRVMLNDNESYNIETSVFQAPRFKGEGKYAVQQGA
                     GMAVTKSTKEEEYASVEFLKWFTDKEPNIKFSIASGYLPVKKKTNDLNVIKEVMKKDN
                     LSLSDKVEGSIASSIEQINSCNLYTNKAFDGGTKARQILEYSMLDKAKEDSNKINELV
                     KSGTSKKDAVAQFNNDKNFETWFESFKAELENAIKK"
     gene            7375..10404
                     /locus_tag="JAM15_15650"
     CDS             7375..10404
                     /locus_tag="JAM15_15650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HAT6799683.1"
                     /translation="MENNLRKNNSIMKKMIFPLIIVMLIQTSLFCATILWGGTIKKLN
                     DNSFDILNERVINRKNYIQNEMLQRWSNTSETEATINSSVKKILNEKNALIEDVGNNE
                     EINKDIIKSISNDLIYLLRKNSVTGAFIILNDKNINDKPIDSKGEISRTGLYIRDLDP
                     KFNPNDNSDLLIERGSSDIARSFGISMDSYWEPKFSFKSENEQEGDDFFYKPFRAAID
                     NPNVSSSNLGYWGSKFLLTNAGDRLMTYTVPLIYEDGTVYGVLGIDLSVNYLRELLPY
                     SEINGNKKGNYILGVDRNNDMAFENVISNGYSLKEKFWDGLHSNLEQKESYKNIYKIK
                     NKDNECGNGNIYASVQYLDLYNSNTPFENERWALLGIIEEKSLLSFSKRIEKLVIISI
                     AISLLIGLIGIYIASRLFTKPIVLLANKVRNSNPSKPVNLDKINISEIDELSSAIELL
                     SANVADSSSKLSQIIEMVDMPIGAFELYKNAENVFCTKEFFSVFTTESKFEEYGYMEK
                     NKFLKNLRGLDKYLQESYETENTYIYKFESKDKKLKWIRMNIFEDELKVLGVVVDVTK
                     EFIEKRKIEYERDFDILTNLLNRRAFHSQIQEKFKNKDELKIAAFIMWDLDNLKYIND
                     TYGHDAGDEYIRCAADILKKFISWNGIVSRLSGDEFYVFIYGYESKDSIRDIINSVKK
                     QMNNTLLKLHDGTEFKIRASAGISWYPDDSTNYDELMRYADFAMYQIKNTIKGEVSEF
                     DINIYNKDSFLLSNREELNKLIDGQLVEYAFQPIVDCKGKVFAYEALMRPKIKTFSSP
                     IDVIRLARSQSKLYQIERITWFKALKSFKKYKEKFGDCKLFLNSIPNNNLSKVDFEEI
                     EDLYGEYLNRVVLEITENDKINEDFIEKKKAYIDHWNIEIALDDFGTGYNGDAVLLYI
                     MPDYVKIDMSIVRGIDKDENRQKILKNLISYSNERNIKVISEGVETKGEMETLINLGV
                     DYMQGYYISKPSFIPEDISDKIKKELKICHENRNDVV"
     gene            10481..12547
                     /locus_tag="JAM15_15655"
     CDS             10481..12547
                     /locus_tag="JAM15_15655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAT6799684.1"
                     /translation="MVELIITTNIDIRKLNENQLEAVEHIDGPCMILAGPGSGKTRVI
                     TYRIANMVVNKNIAPTRILAISFTKASSIEMKNRALNLSDDIRLNKVTYGTFHSVFFK
                     ILRYFERYNLDSIFDEKSKRMTIKAILKSLNIENADDDENIGQVINEISYVKNELMDK
                     NEFNSEVLTKDEFLKVYNLYEEQKSKVNKIDFDDMLIRTYYLLLNNKSALEMVRNVYK
                     YILIDEFQDINKVQFEVLKLICSPLNNIFAVGDEDQSIYGFRGARPDFLLEFEQYFNN
                     TKKIILDINYRSKSEIVYTANRLIDKNKNRYEKVIKCSQGDGGSVTYISPHDSEEEAL
                     YIAKEIIDEIQKDYVEYSDFAVIYRTNIQSRALVDVFMDMRIPFVVKDSVITIYDHWA
                     SQDILAYLRIGINPKSNKDWLRIINKPFRYISKDSINMVKDEKDFITALINKCNLHPK
                     QVKTINDLEIDLSYLNTLNPKNAISYIRTSLDYDRYVLDYCSNRKKKTNGLVEILNEL
                     ESSATNFNTVTEFLEHIDRVKTELTENNKNKQTEGVIFTTMHSAKGLEFRNVYIIGVN
                     EGTIPHEKSYDICKEEKKEEQLEEERRLMYVAITRAEEKLCISSTLNKYGKKVDKSLF
                     INDIKSPTKKEIDSIGVGDKVYHKKFHEGEIIKKDGIMFTIKFKDRERILDLKTCLLK
                     NIIYTI"
     misc_binding    13180..13390
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            13616..14431
                     /locus_tag="JAM15_15660"
     CDS             13616..14431
                     /locus_tag="JAM15_15660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HAT6799685.1"
                     /translation="MKVFKKLLSLGLVLGLTLSLVGCSGGGEKTKLEQIKDNGKLVVG
                     TSAEFPPFEFHKVVDGKDSIKGFDIMLAEEFAKELGVKVEIKDMSFDGLIGALNADQV
                     DIVLAGMSPTPEREKSVDFSELYYLSRNAVIVKDADIDKVKTEDDLKKLRVGVQAGSI
                     QEEYVVNTLKMTTTKSLKAIPDLITELKNGNIDAVVTNEAVSLINVKKYDGIKMANTE
                     VGKDVTEGMAAAIKKSDNNKDFIELLNKKIKELQDGKKIEEFLNEASTEAASN"
     gene            14459..15136
                     /locus_tag="JAM15_15665"
     CDS             14459..15136
                     /locus_tag="JAM15_15665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAT6799686.1"
                     /translation="MSLDFSFLSRFGTSFLEGTGVTVSISLVALCFGFIIGIIICMAK
                     ISKSKVLRAISSIYIEVLRGTPLLVQIYIVWFGLPQLGIRFPMLFGIPSEFIASAFAL
                     SVNSGAYVAEILRSGIQSVDNGQMEASRSLGLNYWSTMRYIIIPQAIKNILPSLANEF
                     ITLVKESSIISVIGVVEIMRTADIVKNAAFRALEPLIVAAAIYFVITFTLSRLVGLLE
                     KKLSVSN"
     gene            15195..15917
                     /locus_tag="JAM15_15670"
     CDS             15195..15917
                     /locus_tag="JAM15_15670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004398740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAT6799687.1"
                     /translation="MITIKNLSKSFGDLNVLKNIDLEIAKGEIMVIVGPSGSGKSTLL
                     RCMNLLEIPTGGEIIFEGKNLVDKKTNIDEVRQNIGMVFQNFNLFPHKTILDNITLAP
                     IKLKKMTKEEAEKKAEILLSRVGLLDKKDSYPSQLSGGQKQRIAIARALAMEPDMMLF
                     DEPTSALDPEMVNEVLDVIKELAKEGMTMAIVTHEMGFAKEVADRVIFIDGGSILEDN
                     TPEEVFGNPKHERTKAFLAKVL"
BASE COUNT         6568 a         1593 c         2772 g         5359 t
ORIGIN      
        1 agaataatag gacttagaat taatctatct tatttatata aacattctta tataagattg
       61 tagataagct tgtatttaca caaatctata gaccttctct attatattga cttagtaatt
      121 ataaatacta ttttgcgttt aaagttatta tttcataagt ttatcgtttt ccattattat
      181 agggtcaggc aattcaattt caccttctga catcttcaat ctattaaaca tataattttt
      241 tacatcttct ttatttttaa atttagtaac ttgataaggt gatgtaacac catatttttc
      301 taaaaataga atgccatttt tagttttaat acatatgcct gtatgaccta taaatacgtt
      361 tttagtttct ggataacgaa gaaatccatt tataatagat atatttttat tatttttaaa
      421 agatattttt ctttttttcc attcattttt tatttgttct gcaattttga ttgtatcatc
      481 tgtatcttta gctggtattg cagaaaagaa gttgataaat ttttctacat ctttggtgct
      541 aaatttagca tctttattat tcattatagt gtctaagtcg acattcaaat caatagagtc
      601 tccagtaaat ttcttatttg aatttataaa atctttaaaa agtctaaaag cagttattct
      661 acaatttaca tccatataat cagggaattt tttcacccaa ttatcttgca atttttctag
      721 gttatatgga acttgttttg cattgattga agaatatcca gatttagata tatttatatt
      781 attttgaagt attttaactt gcaatttatt ataattgttg actgctttaa taaatgtatc
      841 tatgtctttt tcattaattt tattttcttt taggatttcc tttacactat tttgagtttt
      901 tttatctatc atattagaat atatcaattt attattatta tatttaatat ttgaatatgc
      961 aaatatcgta agtatacttg atagtactaa gacaacagac aatatcatta ttattaatct
     1021 ttttttcata tttagttctc ctttttaaat ttattgtgtc gacatattta tagtatatag
     1081 tacctttaaa tttaccttca atatgttttt aattacaaaa ctgttgtaaa aaatataact
     1141 ttatttaaaa ctttttttta atatataaat atatatacta atagggggta cttattttta
     1201 gaatattcag taaaataatt ttgatatact ctatatattt tgtatgttaa aagtaaataa
     1261 attattgtta aagaaggtaa agacttttaa attttttatc acaggatttt aagtaaataa
     1321 gaaggattgg agtaattaaa aatttttatt ttgcaaaaat aagtatttat ttatatggat
     1381 aaatttgatt ttaaatctat caatatagat aaaatcttat tatttaactt caactattcc
     1441 ttaaaaaagc aacttttaag gaatagttga aacaaaaagt ttggttacat aatagtaatt
     1501 ttagttacaa gaatgaaact gtaaaactta ggattttctt tatataattt cattgagaac
     1561 atttaattta ggaggtaagg tatgaaagta aaaaaattta aaagtggtat agtaatggca
     1621 ttaacagtaa tggcaattgg agcatcattg acaaatgtat cagctatgga attaaacaag
     1681 agtaaagagt ttgaaactaa atacaatgaa atgaagaggg attttcaaga ggattatgga
     1741 aaagaagaca aatttaatat aacattggat gatgaattta caaaagaaga agtaaatgga
     1801 gctaaaggga ttataaagac aactaataaa atgaataatg aggttgtagt attaaattat
     1861 tttgatgaaa tgaaatctgg gattgaattt gagttgaagc caaaagcaga aaaaaatgca
     1921 attttgagag atgaatttca acaaggttat ggaaaggaag ataaattcaa agttgtgtta
     1981 gatgatgaat ttacaaaaga agaggtaaat ggagctaagg gcattataaa gactacagat
     2041 aaagagacag gtgaggttat cgtatataat tactttgatg agcttgaaaa ataatgctta
     2101 aagattactt tgattgaatg aaaaggtaat tgtgttgaga atattaaatg actgaataaa
     2161 aacagttgta tcaaaacaaa caataataga atgtaagaat gattgtgtcg aaaatataaa
     2221 atgactaaat aaaaaacgat tgcgtcaaaa ataaacaata atagaatgta agaataattg
     2281 tgtcgaaaat ataaaatgac tgaataaaaa cagttgtatc aaaacaaaca ataatagaat
     2341 gtaagaatga ttgtgtcgaa aatataaaat gactgaataa aaaacgattg tgtcaaaaac
     2401 aaaaaataat taagtgtaag aatgattgta tcaagaatat aaaatgattc aacaaaaaac
     2461 gattgtgtca aaaacaaaaa ataattaagt gtaagaatga ttgtatcaag aatataaaat
     2521 gattgaataa aaaacgattg cgtcaaaaat ataaaataaa ttaaaagaaa aagattatat
     2581 tgaaggaaaa agacttgaag taggggtgaa ctttacatat tatagttcac ccttatacaa
     2641 aaatataaaa tataatttat tataggaaaa tttaaaaaaa tcagtctatt taatttatac
     2701 tgatatattg taggatttta caaacaaact gttatataac tttttttatc tccaattttg
     2761 attttaagat atctaagaat ttataacaat cttctggata tatttctccc atatttgcta
     2821 cttggaatat attagcatct aggaatttgc cttttcctgg atagacaaca tagccacttt
     2881 ccctttctag ccctaatata aactcattta cattgatttc tttaggtaga aatacagatg
     2941 ttactgtatt agacatatac ttatctggaa gtaaaaatgt tagacccaat tcttccatac
     3001 cattccttaa aatagcagaa cattctttgt atctttctat tttactgtca tcttccaaaa
     3061 actcagttaa agcttcatta agggcaaata ttaaagtaac attaggtgta tttggtgttt
     3121 gagaagatga tttagcaact ttatagtgtt tataaagatt aagatacaca ttcttacatt
     3181 gattttcttt aatattttgt aaaatactct ctttagcaca aaggtatgca gaacctggaa
     3241 atgctccaag agctttacca ccaacacctg ttattatatc tattaagtca gagtttaggt
     3301 atatttgtta atgtatgtat atttatcaaa taatattata agtgttatgc aagataattt
     3361 taccatattt aaaacttaca tttaagcaaa aaaataaaaa tagatgttta ataattcaaa
     3421 ataactcaaa ttttataaaa caattgacta aaatatgatt ttattatata atttactagt
     3481 atagagatat ggagaagtac tcaagtggct caagaggatc ccctgctaag ggattaggct
     3541 gggtaaccgg tgcgagggtt cgaatccctc cttctccgcc aattattaaa ggctattttt
     3601 attaaagata gtctttttat aatgtcataa atgattagat atgtataact aaagaaagga
     3661 gggaatagat gacaacttta atttttttca tagtggggat agcatctttg gtagttgctt
     3721 ttgttattga tgggggacat gttggagcat tatttgtatt ttcatcagca cttgttgtgt
     3781 ttggtggaac tataggagct gttggagctt cgactccatt ccctgtgttt aaaaagtcta
     3841 taaagataat gttattagct tttaaaaata aaaagcctaa taacatagaa aatataatct
     3901 atttcaaaga aattgcaaca aaggctagga aagaggggct tcttagtatt gacaaagaaa
     3961 taagtgagaa tgatgaatta gaccctttta ttagaaaagg gcttgaactt atggtagatg
     4021 gagtggatgc agttactata agaaatatat tggaatcaca gatacagata acatcaaaac
     4081 gacataaaga aggaatagca atttttgatt cagcaggtgg atatgcacct acactgggga
     4141 taataggtac agttatggga ttagtacata ttttaggtaa tctttcaagt aatccagatg
     4201 cattaggacc tcaaatttct gttgcatttt tggctacttt gtatggtgtt ggttctgcca
     4261 atttaatatg gttaccaata gcatcaaaac ttaaggctat aaatcaacaa gaagtaagtg
     4321 aaagactttt ggtgatagaa gcaatattat ccatacttga gggtgataat tctaatttaa
     4381 tgacagaaaa attaaaaata tttttaaatt caaaagaact aattgaactt gaagaaattg
     4441 gtggtagagc tgaataatat aaaaggatgg aatgtttatg ttgtatgatg aagatgaaaa
     4501 agaagaaaac aatgagcgat ggcttttaac ttattcagac ctcataacat tacttatgat
     4561 tttctttgta ataatgtatt ctatgagtaa tgttgatgcg gagaaatata aacaattatc
     4621 tcaatctcta aattctgctt ttggtggttc ttctggagtt attgaaggtg gtaatagcaa
     4681 gatagaacca gtagttgaac caggaagtaa tgatttagat actttacaaa atgctaagtt
     4741 taaaaaagtt ggtgaagaaa tccagaagta tttaaatgaa aatggtatgg ctaattcagt
     4801 atcattaaga gttcaagata gaggattagt aataagcctt aaagatacaa tactatttga
     4861 tacaggaaaa gcagttgtaa aggataattc tagagataag attattcaaa taggtaagat
     4921 gttaaatgaa atgaatagtt acatgagagt agaaggtcat acagacaata tgtctataaa
     4981 aaattcagag tttaagtcaa attgggattt atcagttatg agagcaacca atgttgttca
     5041 acttcttatt gacaatgcag gtatagcacc agataaattg tctgctgtag gatatggtga
     5101 gtttagacca atagcagaaa attcatctga agaaggtagg tcaaaaaata gaagagttga
     5161 tatagtttta gttgatagta aatatgataa tgtagaaaat gtttcaaagg ataaatagtt
     5221 aaattagctg tctcaataca gaattaattc taaaggagat ggctttttta tgcgaaaatt
     5281 aaaaatagat acatagtaag ttaccttttt gtaggaatat atggtatctt aaatatataa
     5341 tatttaaata atatataagc tcaattaaaa aaattttata gaggatggga aataaatggg
     5401 aaataaaaat aaaaatacga aatataaaga taaaacaaga gaaagatata ataaaaaagt
     5461 tgagaattta aataaagaaa aattaaataa agataataaa cagtctaaga aggtagataa
     5521 gattgatgat attattaata aatctagtat tgtattatgt gtacttctag tagtgttttc
     5581 attactttac ttatttaaat tggttcaact taatataata atgatacttt tagtaattac
     5641 agtagctatt caacaaggat tggtgtcatt tggtgcattt agaaataaaa attatgtaaa
     5701 agctttattt tctatatttg taatagtatg tttcttaatt gcttttaaat atgttgtaaa
     5761 tcctgtttaa atatatcaat aaacgttcta taattaatat aaatagtgaa gttacagttt
     5821 taatgctatt ataaatttta taatttgaag gagtagattt tatgaatagg tgtaagtttg
     5881 caaaattaat tatcacatca atgattgttt tattacttac aggatgtagt ttaaaaaagg
     5941 aagataatta taagttagac ccagaaaatc cgacatcaat acaaatttgg cattattata
     6001 atggacagca aaaaatggct tttgataagc ttgttaagga atttaatgac actataggtg
     6061 ctgaaaaagg aattattgtt gaagcgttta gtcaaggtaa tgtagttgat ttatcagaga
     6121 aagttttaga ttctgcaaat aaaaaagttg gatctgaaga tgtgccaaat atatttgcag
     6181 catactcaga tactgcatat gaaatggata aattagggtt actagtagat atggataagt
     6241 acataagtaa agaagaatta aatgaataca tagacgaata tgtagaagaa ggcagaataa
     6301 attctaagga tgagtttaaa cttttcccaa ttgcaaaatc aactgaaatt ttgatgttaa
     6361 ataaaactga ttgggataaa tttgcaaaag ctacaaattc aaatataaat gatataaaaa
     6421 caattgaagg attagtagag acatcaaaaa aatattatga atggacagat agtttaacga
     6481 aagagcctaa tgatggtaaa gcattttttg ggagagatgc tttagcaaat tatattatta
     6541 taggaagtaa acaactagga gtagaaattt tttctgttaa agatggtaaa gttacactaa
     6601 atattgaaga aaaagttatg aaaaagctat gggataattt ctatgtacca tatataaatg
     6661 gatattttgc ttcttatggt aagtttcgtt ctgatgatgc aaaaacaggt gatatattag
     6721 ctcttgtagg ctctagttca ggagcagcat actttccaga tagagtaatg ctaaatgata
     6781 atgagagtta taatattgaa acatctgttt ttcaagcacc acgttttaaa ggagaaggaa
     6841 aatatgctgt acaacaaggt gcaggaatgg ctgtaacaaa atctactaaa gaagaagaat
     6901 atgcatcagt agaattttta aaatggttta cagataaaga gcctaatata aaattctcta
     6961 ttgcttctgg atatttacca gtaaagaaaa aaacgaatga tttgaatgtt ataaaagaag
     7021 ttatgaagaa agataatttg agtttatctg ataaagttga aggttcaata gcctcatcta
     7081 ttgaacaaat taacagttgt aatttataca ctaataaagc atttgatggt ggaactaaag
     7141 ctagacaaat acttgaatat tcaatgcttg ataaagctaa agaagattca aataaaataa
     7201 atgaattagt aaaaagtgga acttctaaga aggatgcggt agcacaattt aataatgata
     7261 agaattttga aacttggttt gaaagtttta aggctgagct tgaaaatgct ataaaaaaat
     7321 agatgaattg gcagttagtg tgtagacaag cacaaaggta taggtggaat aagtatggaa
     7381 aacaatctaa gaaaaaacaa ttcaataatg aaaaagatga tatttcccct aattattgtt
     7441 atgctaattc aaacaagttt attttgtgcc acaattttat ggggaggaac tattaagaaa
     7501 ttaaatgata attcgtttga catcttaaat gaaagagtaa ttaatcgtaa aaattatata
     7561 caaaatgaaa tgttacaaag atggtcaaat acaagtgaaa cggaagctac aattaattcc
     7621 tctgtaaaaa aaatattaaa tgaaaaaaat gccttaattg aggatgtagg caacaatgaa
     7681 gaaattaaca aagatattat aaaaagcata tcaaatgatt taatatatct tttgagaaaa
     7741 aactctgtta caggagcttt tataattcta aatgacaaaa atattaacga taagccaata
     7801 gatagtaaag gtgaaataag taggactgga ttgtatataa gggatttaga ccctaagttt
     7861 aatccaaatg ataattctga tttgttaatt gagagaggtt catcagatat agcaagaagt
     7921 tttggaatat ctatggacag ttattgggaa cctaaatttt catttaaaag tgaaaatgag
     7981 caagagggag atgatttttt ttataaacca tttagagctg caattgataa tccaaacgta
     8041 tcaagttcta atttgggata ctggggaagt aagtttttat tgacaaatgc aggtgatagg
     8101 cttatgacat atacagttcc ccttatttat gaagatggaa ctgtatatgg agtacttgga
     8161 atagatttaa gtgtaaatta tttaagagaa ttacttccat actcagagat aaatggaaat
     8221 aaaaaaggta attatatttt aggtgtagat agaaataatg atatggcctt tgaaaatgta
     8281 atttcaaatg gatactcatt aaaagaaaaa ttttgggatg gtttacattc taatttagag
     8341 cagaaggaat cgtataaaaa tatatataag attaaaaata aagataatga atgtggtaat
     8401 ggcaacattt atgctagtgt acaatactta gatttatata actccaatac tccatttgaa
     8461 aatgaacgtt gggctctttt gggtattatt gaagaaaaaa gtcttttgtc attttcaaaa
     8521 aggatagaga aattagttat aatatctata gcaatttctt tattaatagg tctaataggt
     8581 atttacattg catcaagatt atttacaaaa ccaattgttc ttttagccaa caaagttaga
     8641 aacagtaatc catcaaaacc agtaaatctt gataagataa atatatctga aatagatgaa
     8701 ttatcttcag ctatagagtt actcagtgca aatgttgcag attcttcatc aaaattatca
     8761 cagattattg aaatggtaga tatgccaatc ggggcttttg agttatacaa aaacgcagag
     8821 aatgtttttt gtacaaaaga attttttagc gtgtttacta ctgaaagcaa atttgaagaa
     8881 tatggctata tggaaaaaaa taagttcctt aaaaatttaa ggggactaga taaatatttg
     8941 caagaaagtt atgaaacaga aaatacatat atatataagt ttgaatctaa agataaaaaa
     9001 cttaagtgga taagaatgaa tatctttgaa gatgagctaa aggttcttgg tgttgttgtt
     9061 gatgtcacaa aagaatttat tgagaaaagg aagatagaat atgaaagaga ttttgatatt
     9121 ttaacgaatc ttttaaatag gagagctttt cattcacaga tacaagaaaa atttaagaat
     9181 aaagatgaac ttaagatagc agcatttatt atgtgggatt tagataatct aaaatatatt
     9241 aatgatacat atggacatga tgctggtgat gaatatatta ggtgcgctgc agacatactt
     9301 aagaagttta tatcatggaa tggtatagta tctagacttt caggtgatga gttttatgta
     9361 tttatatatg gatatgaaag taaagatagt ataagagata ttattaattc tgttaagaaa
     9421 cagatgaata ataccttatt aaaacttcat gatggaacag aatttaaaat aagggcatca
     9481 gcaggaattt cctggtaccc tgatgattca accaactatg atgaattaat gagatacgca
     9541 gattttgcta tgtatcaaat taaaaataca atcaaggggg aagttagtga atttgatatt
     9601 aatatatata ataaggattc attcttattg agtaatagag aagaattaaa caagttaatt
     9661 gatggtcaat tagttgagta tgcatttcag cctattgtag attgtaaagg taaagtattt
     9721 gcatatgagg cacttatgag acctaaaata aaaactttta gttcaccaat agatgtaatt
     9781 agattagctc gttcacagtc taaattatat caaattgagc gtattacatg gtttaaagca
     9841 cttaaatcat ttaaaaaata caaagaaaaa tttggcgatt gcaaactgtt cttaaattct
     9901 attcctaata ataatttatc aaaagtagat tttgaggaaa ttgaagattt atatggtgaa
     9961 tatttaaata gagtagtatt agaaataaca gagaatgata agattaatga agattttatt
    10021 gagaaaaaga aagcatatat agaccattgg aatatagaaa ttgctttaga tgactttggg
    10081 acaggttaca acggagatgc tgtactatta tatataatgc cagactatgt aaagattgat
    10141 atgtctattg taagaggtat tgataaagat gaaaacagac agaaaatatt aaaaaatctt
    10201 atctcatatt ctaacgaaag aaatattaaa gtgatatcag aaggtgtaga aacaaaaggt
    10261 gaaatggaaa cactgattaa tcttggagta gattatatgc agggttacta tattagtaaa
    10321 ccatcattta tacctgaaga tataagtgac aaaattaaaa aagagctcaa gatatgtcat
    10381 gaaaatagga atgatgtggt ttaatagagg aaaaattaaa tttattttta tgaactttta
    10441 gtttataatt aaaaagaaaa taatataatt ataaattaag gtggtggagc taataatcac
    10501 aacaaacata gatataagaa agttaaatga aaatcaatta gaagcagttg aacatataga
    10561 tgggccttgc atgatacttg cagggcctgg ttcaggtaag accagagtaa ttacatatag
    10621 aatagccaat atggttgtaa acaaaaatat agcaccaaca agaatcttgg caataagttt
    10681 taccaaggca tcttcaatag aaatgaaaaa tagagctttg aatttaagtg atgatataag
    10741 acttaataag gtaacctatg gtacttttca ctctgtattt tttaaaattc taagatactt
    10801 tgaaagatac aatttagaca gtatatttga tgaaaagtca aagcgaatga caatcaaggc
    10861 aatcctaaaa agtttaaata tagagaatgc tgatgatgat gagaatatag gacaagttat
    10921 aaatgaaatt tcctatgtaa aaaatgaact tatggataaa aatgaattta attcagaagt
    10981 attaacaaaa gatgagtttt taaaagtata caacttatac gaagaacaaa aatctaaagt
    11041 taacaaaata gattttgatg atatgcttat aagaacttat tatttacttt tgaacaataa
    11101 gtctgcacta gaaatggtta gaaatgtgta taaatatata ttgatagatg aatttcaaga
    11161 tataaataaa gtacagtttg aagttttaaa gttaatttgt agcccattaa acaatatatt
    11221 tgcagttgga gatgaagacc aaagtatata tggatttaga ggtgctagac cagatttttt
    11281 gcttgaattt gaacaatact ttaataatac taaaaaaata atattagata taaattatag
    11341 gtctaaaagt gagatagtgt atactgcaaa tagacttatc gacaaaaata aaaatagata
    11401 tgaaaaagtc attaagtgta gtcaggggga tggaggaagt gttacctaca tttctccaca
    11461 tgattcagag gaagaagcct tatatattgc caaggaaata attgacgaaa tacaaaaaga
    11521 ttatgtagag tattcagatt ttgcagtaat ttatagaaca aatatacagt caagagcatt
    11581 agtagatgta tttatggata tgaggattcc atttgtagta aaagactcag taattacaat
    11641 atatgaccat tgggcaagtc aagatatact agcttattta agaataggta ttaatccaaa
    11701 atcaaataaa gattggttga gaattataaa caagcctttt agatatatat ccaaagacag
    11761 tataaatatg gttaaggatg aaaaagactt tataacagca ttaataaata agtgtaatct
    11821 tcatcctaaa caagttaaaa caataaatga tttggaaata gatttaagtt atttaaatac
    11881 tttaaatcct aaaaatgcaa tatcttatat tagaactagt cttgattatg atagatacgt
    11941 tttagattat tgtagcaaca gaaagaaaaa aactaatgga cttgtagaga tattaaatga
    12001 acttgagagt tcagcaacta attttaatac tgttacagag tttttagagc atattgatag
    12061 agtaaagact gagttaacgg aaaataacaa gaataagcag actgagggtg tcatatttac
    12121 aactatgcat agtgcaaaag gattagaatt tagaaatgtt tatattatag gtgtaaatga
    12181 aggaacaata cctcatgaaa aatcatatga tatttgtaag gaagagaaaa aagaagaaca
    12241 attagaagaa gaaagaagac ttatgtatgt tgctattaca agagctgaag aaaagttatg
    12301 tataagctct actttaaata agtatggtaa gaaagttgat aaatcattat ttattaatga
    12361 tataaaatct ccaacgaaaa aagaaattga cagtattggt gtaggggata aggtatacca
    12421 taaaaaattt catgaaggag aaataattaa aaaagatgga attatgttta caataaagtt
    12481 taaagataga gagcgaatct tggatttgaa aacttgttta ttgaagaata taatttatac
    12541 tatttaattt agaatctaaa tttagataga aatataatgt attatttatt atgtgcaaga
    12601 caaatagata tgtgtaaaat gtattattta acttattaga aaaagaaata aggatttaat
    12661 atattattta tagttgttta gaaaaagcaa caatgtggaa aatattattt agtattatta
    12721 aagaaaagca acaatgtgga aaatattatt tagtattatt aaagaaaagc aacaatgtga
    12781 aagatattat ttagtgtaat ttaagaaaaa gcaacaatgt gaaagatatt atttagtatt
    12841 attaaagaaa gagcaacagt gtgaaagata ctatttagta ttattaaaga aaaagcaaca
    12901 gtgtgaaaga tattatttag tgtaatttaa gaaaagcaac aatgtgaaag atattattta
    12961 gtattgttta agaaaaagca acaatgtgaa agatattatt tagtattatt taagaaatag
    13021 ctaaaaatat gaaatatact atttataatt acaaaaataa tatcaataaa tataaacagt
    13081 agtatttaga taatttacaa gtaaaaatta ttaaaaaaat aaaaaactta ttgacaaaaa
    13141 tattataagg aagtacaatt gtattaacaa tttaaggaaa caaatccaat gatagagaaa
    13201 gtagcatata tggatttaca gcgagttagg ggttggtgta agcctagcaa tgaagtctat
    13261 gtgaagagag ctctggagga gattatcaga aactttagta tgataattgg tttacccgcc
    13321 ttaagggatt gagaggataa gtacttactt atcaaaaaga gtggtaacgc ggatataatt
    13381 cgtctcttag ctgtaaagct aagggacttt tttgatttaa aaataaaaat atccatacag
    13441 cttaaatgct aacagtcaca aattttgaaa gtaatataag tatttatcaa taagagtggt
    13501 aacgcggtaa agtcgtctct tagtcattaa agactgagag actttttttg taactcgaaa
    13561 catttaagta ttaaaatctg agggaaatta taattaaaag agaggggtag ttaaaatgaa
    13621 agtatttaaa aaattattaa gtttaggatt agtattagga ttgacattat cgctagtagg
    13681 atgtagtggt ggaggagaaa aaacaaagtt agaacaaata aaagacaatg gaaaattagt
    13741 tgttggtact agtgcagaat ttcctccatt tgaatttcat aaggtagtag atggaaaaga
    13801 ttcaataaaa ggattcgata taatgttggc tgaagaattt gcaaaagagc ttggtgtaaa
    13861 ggttgaaatt aaggatatgt catttgatgg attaataggt gctttaaatg cagaccaagt
    13921 tgatattgtt cttgcaggta tgtctccaac accagagaga gaaaagagtg ttgatttttc
    13981 agaattatat tatttaagta gaaatgcagt tatagttaaa gatgcagata tagacaaagt
    14041 aaaaactgaa gatgatttaa agaaacttag agttggagtt caagcaggaa gtatccaaga
    14101 agaatatgta gttaacactt taaaaatgac aactacaaaa tctttaaaag caatacctga
    14161 tttaattaca gaattaaaaa atggaaacat agatgcagtt gttactaatg aagcagtttc
    14221 tttaataaat gttaaaaaat atgatggaat aaaaatggca aatactgaag ttggtaaaga
    14281 tgtaacagaa ggtatggcag cagcaatcaa aaaatctgac aataacaaag attttataga
    14341 attattaaac aaaaagataa aagaattaca agatggtaag aagatagaag aatttttaaa
    14401 tgaagcatct actgaagctg cttcaaatta gtaagaaagt tatgtgggag atgaaattat
    14461 gagtttagat tttagttttt taagtagatt tgggacttct tttttggaag gaacaggtgt
    14521 gacagtatca atttctcttg tggcattatg ctttggattt ataataggta taattatctg
    14581 tatggcaaaa atatcaaaga gcaaagtatt aagagcaata tcatcaattt atattgaggt
    14641 tttaagaggg acaccattat tagtacagat atatatagta tggtttggtt tacctcaatt
    14701 aggaataaga ttccctatgt tgtttggtat accaagtgaa tttatagcta gtgcatttgc
    14761 attatcagta aactctggtg catacgtggc agagatactt agatcaggta tacaatcagt
    14821 tgataatgga caaatggaag caagtagatc attaggatta aattattggt caactatgag
    14881 atatataata atacctcaag ctataaaaaa tatattacct tcattagcaa atgagtttat
    14941 tacacttgta aaagaatctt caataatatc tgtaatagga gttgttgaga taatgcgtac
    15001 tgctgatata gtaaaaaatg cagcatttag agcattagag ccattaatag tagcagcagc
    15061 aatttacttt gttataacat ttactctatc aagattagtt ggattattag aaaagaaact
    15121 atctgtgtct aactagatga gagcatgttt agcatttagg gaaaacatag aatagtaaaa
    15181 aggaaagtga taatatgatt acaataaaaa atttaagtaa atcttttgga gatttaaatg
    15241 tattaaaaaa tatagactta gaaatcgcta aaggcgaaat aatggttata gtaggtccaa
    15301 gtggttctgg taaaagtaca cttcttagat gtatgaattt actagaaata cctacaggtg
    15361 gagaaataat atttgaagga aaaaatttgg tcgataaaaa aactaatatt gatgaggtta
    15421 gacaaaatat aggtatggtg tttcaaaact ttaatttatt cccacataag actattttag
    15481 ataatataac attagcacca attaaattaa aaaagatgac taaggaagaa gcagaaaaaa
    15541 aagcagaaat tttgttgagt agagttggtc ttttagataa aaaagattca tatccatcac
    15601 aattatctgg aggacaaaag caaagaatag caatagctag agcacttgct atggaaccag
    15661 atatgatgtt gtttgatgag ccgacatctg ctcttgaccc agaaatggta aacgaagttt
    15721 tggatgttat aaaagaactt gctaaagaag gtatgacaat ggcaattgta actcatgaga
    15781 tgggatttgc taaggaagtt gcagatagag ttatttttat agatggagga agtatacttg
    15841 aagataatac tccagaagaa gttttcggaa atccaaaaca tgaaagaaca aaagcatttt
    15901 tagcaaaagt gctataatat ataaaaagga tgttattgat attagaaatt caatacatcc
    15961 ttttttagtg atggttaata ttaattttaa aattaaagtt atattaatat taactttatt
    16021 tttacgattt tttgcagaaa aaaaaagagc tcggggtaag ctcttttttt ccaccgaatt
    16081 aatttccgtt actaatccga tttttaataa atataaaata tatccttatg aaagggtatt
    16141 gggaatagat atattaacta actagggtta ccagggggat aaccttaatt tattataaca
    16201 aaatgcgaca caaaaatcaa tatttttttt gaaataaatt ataaaagtta tttttataac
    16261 aagtaagctt ataaatttaa cttttatagt aa
//
LOCUS       DACTZW010000091        16277 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.091, whole genome shotgun sequence.
ACCESSION   DACTZW010000091 DACTZW010000000
VERSION     DACTZW010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16277
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.091"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(84..995)
                     /locus_tag="JAM15_15675"
     CDS             complement(84..995)
                     /locus_tag="JAM15_15675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HAT6799688.1"
                     /translation="MSRAERLIELMITINAKRSFTAGELAEEFSVSKRTILRDLQVLE
                     SIGFPLYSKVGAAGGYHVLKERILPPIAFSESEVKSIFFAYQSLEYYNDLPFEQETIS
                     VLKKFLNCIPNDIQYNIENIRRKFVFWTPDRHCSTPLLKELFNIVMNESTIKIEYSSK
                     QKNSVRTIVPIGLYAMNGLWYCPAYCIKSESIKEFRVDRIVKILSIENLSSKKYKVLS
                     SIHDYLKNMEVGTDYHIKINLTDEGVKRCETEFLLARGLKILSKGGYIDMYIPKSTLN
                     WVAEYFLTFGKNATIIEPIELKHLIKK"
     gene            1110..1577
                     /locus_tag="JAM15_15680"
     CDS             1110..1577
                     /locus_tag="JAM15_15680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799689.1"
                     /translation="MENNTIKADDIINYCLSNLDDVLLMNSWGERAIYYNPNGILKRG
                     VYVLTIKEKDSNHDKGSLVSRPNVYRVNIGLKKETFIEMFGYIPKRPGVGQIVDMDFD
                     FTKLDTIMPHPIYSWMGWICVLSPTKKTFENFKTLIGESYNFAKQKFKKRKNK"
     gene            complement(1747..2346)
                     /locus_tag="JAM15_15685"
     CDS             complement(1747..2346)
                     /locus_tag="JAM15_15685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799690.1"
                     /translation="MKLKRTLFVGLALVLAIGITACTKNNEKPSENTGKNPNESVNNN
                     EGYMNYYSTSYNDYIAGLNRYSIYDTPESINNQFKDKEYPGNEKYLSDVKAAYKDSRD
                     KIQSFVTSLKKDGKTEDTELKKMNDDLIAEGERLVKDIDKRIEKLDKVSDEDMKKGQN
                     DFINLVHGTEDVGNDIGSGFRKMIKDMNDRLGITGNNKK"
     gene            2592..3188
                     /locus_tag="JAM15_15690"
     CDS             2592..3188
                     /locus_tag="JAM15_15690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3793 family protein"
                     /protein_id="HAT6799691.1"
                     /translation="MSCCNSQFCCKNKIESSYIKWLLEVLGPVFLGSKPAEIINISFT
                     DVNREEKINDIYKYLYKCKKIDFIVIDKEKKGLKILFVNKKALSEKLKCKKTVNFLKF
                     LGYKQNTNVNAYLEHLVNKLKSDVFPDEIGIFLGYPLKDVIGFMGYSNYEVSMIKYWK
                     VYGDTKQSEDTYSKFLLHRKKMRKLLDYISVDKIVSCF"
     gene            complement(3286..4245)
                     /locus_tag="JAM15_15695"
     CDS             complement(3286..4245)
                     /locus_tag="JAM15_15695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aliphatic sulfonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HAT6799692.1"
                     /translation="MTSLIMVLVGTVGCSTTNDKKDEPAKKEASLPKEINLTYVKSPL
                     NVPSILEKKYDLFGKEFKKDNIKVNFHELTTGPEQTQALAAGELDFLHALGGTSAIIA
                     ASNGVGLKITNIYSRSPKGYMLITNNDNIKSIKDLKGKKIVGPKGTILHQLLIATLAK
                     EGYTIDDVEYVNMDIPSAASALESKSADVAMLAGPVALKTINSGAKMIVNGEGLVSGI
                     IVTAVSDDFAEKYPELVKRFMKVHEETLKYMNENKDEVMDVVSKEVGLSLDETKEMYS
                     WYDFSSKITDKDIKELEDTQEFLMSNGMQQKKINIKDMLYNQN"
     gene            complement(4279..5010)
                     /locus_tag="JAM15_15700"
     CDS             complement(4279..5010)
                     /locus_tag="JAM15_15700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6799693.1"
                     /translation="MVRSGFLLENIYKKYLVDNKEHLVLDNISLNISSEEITVILGES
                     GCGKTTLLRILAGLENATSGNIYFFNNDKKCTPKVGMVFQESRLMPWLNVSENILLHT
                     EKDNRNKVDLDKYLKMMKLEKFKNSYPNELSGGMVHRVSIARALSFNPDILLMDEPFA
                     ALDYFTRRKMQKEVVNIHKNTKKGVVFVTHNIEEAMEIAKKIIVFSKNKRIKQFSVED
                     EYNRDLTKNYYINLKKEILRELGEF"
     gene            complement(5003..5773)
                     /locus_tag="JAM15_15705"
     CDS             complement(5003..5773)
                     /locus_tag="JAM15_15705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6799694.1"
                     /translation="MFEKIHKRFKGYYIFLIILILWKIVCVLGIWSSYILPPPEIVLD
                     TFIKMIYDGSIFLNVYASVRRILIGFLISSLMAIPLGVVFGVNKKMYEYFKPLFEFMR
                     STPPLALVPMLILWFGIGEESKIIIIILASFFPIFLNTLKGIKNCDNKLIEVGKSFNL
                     SKKRIFYKIIIPNSMLDIVVGLSLGLGYSFRAIIGAELIAASSGLGYLISDGKDMSRT
                     DVVLVGIFVIGFLGILSDYLFSKIITKFSKGKQVDLNG"
     gene            complement(5858..6568)
                     /locus_tag="JAM15_15710"
     CDS             complement(5858..6568)
                     /locus_tag="JAM15_15710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HAT6799695.1"
                     /translation="MFKFDVTNELMCIARGSGKFFAKKGAMVAFKGNFNFEKLLLGPS
                     NGGGLGRALLGHVQRSLTGEQMPIMVVEGEGEIYLAQNAYHVDVISIDPGDSIYVESE
                     NLLAFSEQLNYSVKLIGSGVISQKGLFTTHLVNKTGQNQDVAIITDGNPLILEGPCCV
                     DPDALVAWTGREPYPKVSKLSWKTFIGQTSGESYHMEFVEPGQIVIIQPSERLSGLKT
                     DSTPSDRMSSGGLRLGID"
     gene            complement(6748..6900)
                     /locus_tag="JAM15_15715"
     CDS             complement(6748..6900)
                     /locus_tag="JAM15_15715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HAT6799696.1"
                     /translation="MATFIIAAIVVVLMALAVMYMVKNSKKNGSSCGCGCSGCSSSKS
                     CHSAKR"
     gene            complement(6926..9082)
                     /gene="feoB"
                     /locus_tag="JAM15_15720"
     CDS             complement(6926..9082)
                     /gene="feoB"
                     /locus_tag="JAM15_15720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HAT6799697.1"
                     /translation="MSIKIGLIGNPNCGKTTMFNGLTGSSQYVGNWPGVTVEKKGGKL
                     KGNKDVEIVDLPGIYSLSPYTLEEVVTRNFMLDDKPDAVINIVDASNIERNLYLTTQV
                     LELGIPTIIALNMMDIVNKNGDKINIKELSEVIGCPVVEVTAVKGQGIMEAAEKAVEL
                     ASSNNKLNFKLPFVDESKDAIEKIEKIIEEKTPYIDVETRWLAIKLFERDENVIQKLD
                     ISKTILNSIEEITRNCEDELDDDSESIITANRYEFISSIISSIIKKNRKGKETVSDKI
                     DKIVTNRILALPIFALIMWGVYYIAVSSLGTIATNWTNKVLFGEIIKGNVSNFLASLN
                     VAEWLQGLVVDGLVGGVGSVLGFVPQIMLLFLLLSILEDCGYMSRVAFIMDRIFRKFG
                     LSGKSFIPMLISSGCGVPGVMSTRTIENDRDRKMTIMLTTFIPCGAKIPIIALFAGAL
                     FGGASWVAPSMYFLGIAMIIICGIILKKTSLFAGEPSPFVMELPQYHVPSAKGVLIHM
                     WDRGKAFIIKAGTIIFVACGVIWFLQSFNWSLQMVDAGDSILASLGNIVAPIFAPLGF
                     GNWQSSVATVTGLVAKENVVGTFGVLFGISDATEQDPTLLASVASMFTVASAFAFMAF
                     NMLCAPCFAAIGAIKREMGSWKWTWITLGFQTLTAYIIALLINQVGSLVLGTGGSIAG
                     AIISIFIAVAVVFVVLTYSNKNMKKEKMGKLSYMKN"
     gene            complement(9182..9403)
                     /locus_tag="JAM15_15725"
     CDS             complement(9182..9403)
                     /locus_tag="JAM15_15725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015391815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HAT6799698.1"
                     /translation="MNRLKDIKCGETVKVKKLEGEGATRRRIMDMGITRGVNIFIRKV
                     APLGDPIEVTVRDYELSIRKSDAEKIIVE"
     gene            complement(9416..9625)
                     /locus_tag="JAM15_15730"
     CDS             complement(9416..9625)
                     /locus_tag="JAM15_15730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012060355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HAT6799699.1"
                     /translation="MPLILSNTGEEVVIKKISGSDKTRTFLNSIGFVVGTNVKIVSKI
                     DGNLIIDVKDTRVALDKKMASRIII"
     gene            complement(10152..10760)
                     /locus_tag="JAM15_15735"
     CDS             complement(10152..10760)
                     /locus_tag="JAM15_15735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HAT6799700.1"
                     /translation="MVDNLIKYIHKSNIAIVVLHEIYGVNNFIKDVCQKYYKGGYDVF
                     CPELLGEKRVFSYLKAQEAYDFFINNVKFDIYKKVEKLINGLKSEYKHVFVVGYSIGA
                     TIAWRCSENSLCDGIICCYGSRIRDYMDVIPTCPILLVFAKYDSFDVDYVSSQLSRRQ
                     NIQIEILDANHGFIDTYSKNYSNAQTEVFNIKEKNFLSKCLG"
     gene            complement(10880..11308)
                     /locus_tag="JAM15_15740"
     CDS             complement(10880..11308)
                     /locus_tag="JAM15_15740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAT6799701.1"
                     /translation="MYGVIGATVLVIFVILTAGIMQGKKVDFQLPTVFMIVTFIVSAI
                     SEEIVFRGYIQTRLTGLIKNSVLSSCINAFLFLSTHYPVKWISSGDFSFAILSGFYVI
                     CLILLNFSCDLVYRKTNCLWGAWLLHILYNIGTGVLIFTT"
     gene            complement(11327..11587)
                     /locus_tag="JAM15_15745"
     CDS             complement(11327..11587)
                     /locus_tag="JAM15_15745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799702.1"
                     /translation="MFKTVFEDKEYVLLCKNYSKSDGVKAIFIYLISMLLLFFQGYLY
                     TTNLSSTILTNSQMILSILILLIGLGFVLLSKEKLNTIGITM"
     gene            complement(11861..12406)
                     /locus_tag="JAM15_15750"
     CDS             complement(11861..12406)
                     /locus_tag="JAM15_15750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010075074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HAT6799703.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEKNWADE
                     HRIGVAQGVDEEIIEGLRANFVGECTEVGMYLAMSRQADREGYPEVGEAYKRIALEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKKAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRYFGK"
     gene            complement(12523..14346)
                     /locus_tag="JAM15_15755"
     CDS             complement(12523..14346)
                     /locus_tag="JAM15_15755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6799704.1"
                     /translation="MNLSTGNQKVSRLKKKEKPKDFKKTFKRIFMYFKKDKKITRFIF
                     LLVIIDSIISTVIPYTIGKVVDIIDIDTYSKSIFLKGIIILLSFYIIEFSVKLSKGIC
                     TARLSQSIVKEMRSNLFLKFKNLPITFFDKSSTGDIMSRVTNDVDNISTGISNSLVQL
                     ITGILNILMTFIMMFVLSPILTFCSVILIPIVMFVSNFIAKRTRVFFKQQQVELGKLN
                     AHIEEMISNINVVKSFNYERKSVNDFKEVNDRLLNISLKSQIYTSLLMPIMNVISNIG
                     FATICIIGGVLASKDIITIGVIASFLSYVRQFTRPLNELANLFNTLLSAIAGCERVFE
                     IIDEQEEQEVDNVFKSEINDNKNGNLNSHFVKGEIELKDVSFSYDSKKKILDNINLKI
                     KAGTSNAIIGETGSGKTTIINLITNFYHIDEGSIFLDGKDIYSINRNYLRTCFGVVPQ
                     EGYIFNDTVMENIRYGNLEATDEEVIYASKIANAHKFIVKMREGYSTVLSDRGEDLSE
                     GQKQLISIARAVLKNAPILILDEATSNIDIATEAKIQEAINNLTYGKTSIIIAHRLST
                     ISNCDNIIVLENGRIVESGNHKELIKLKGHYYRNILLTQGK"
     gene            complement(14359..16134)
                     /locus_tag="JAM15_15760"
     CDS             complement(14359..16134)
                     /locus_tag="JAM15_15760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6799705.1"
                     /translation="MKYFKKYIKKYIVLFLTAVFFLTLEAFCDLAQPTIMAKIIDIGV
                     SNKNLDYILSTGAIMIGITFLGAVFAIIRSVISARVSQHFSYDLRQDVFEKINTYSLK
                     QIDKFGRASLITRITNDINQMQQFVNGMMRVFIKSPIMCIGSLIIAIKLNLKMSIIIL
                     IAVLIIFIIILLNMKIGYRLFKNVQESTDKVNSKLRQFLSGIKVVKLFCRYDYENQSF
                     EELNDELFKNSRKATTMMSFFRPTITIIINVSIIIILLIGRHLIYSGEIKIGIIVAYV
                     NYMTRILTSLIMISHVFNVFVRAKASYERISEVLVDENEEVIEREESLDVGEKDLKFV
                     NCDIIFENVDFSYNKNTDEKILKNVSFKIEEGQNIGVIGQTGSGKTSLVNLIQKLYII
                     DKGDIKIGGRSIYSISEESLREKIGVVFQNSSVFGKSILENIVMGNEGISREDVIKSC
                     EIANANQFITKLENSYDEVLFQRGKNLSGGQRQRITIARAIAKKPQILILDDCFSAMD
                     INTETIIRKNIKEYISNLREKESKKCTVITISQKISSIIDCDKILVLDEGEVVGFATH
                     EDLLVSSPIYKKIFALQNLVSEDVN"
BASE COUNT         5497 a         2854 c         1639 g         6287 t
ORIGIN      
        1 ttatcctatc tctacatata agtttcccta tatgctgact aatttagcta ctaactcatg
       61 actaaagtca caagtgtgcg tagctatttt ttaatcaaat gtttaagttc tataggttct
      121 attattgtag cattttttcc aaaagttaaa aaatattcag ccacccaatt aagtgtagat
      181 tttggtatat acatatctat gtatccaccc ttagacaaaa ttttcaatcc tcttgccaac
      241 aaaaattctg tttcacaacg ttttactccc tcatctgtca aattaatttt aatatgataa
      301 tctgtaccta cttccatatt cttaagataa tcatgtatag aagataaaac cttatatttc
      361 ttacttgata agttttctat actcaaaatc ttcacaattc tgtctacacg aaattcctta
      421 atagattctg attttataca gtaagctgga caataccaaa gtccattcat ggcatacaaa
      481 ccaataggaa caatggtacg tacactattt ttttgctttg atgaatattc aattttaatt
      541 gtagattcat tcattactat attaaacaat tctttcaata atggtgttga acagtgccta
      601 tctggtgtcc aaaaaacaaa tttacgcctt atattctcaa tattatattg aatatcattt
      661 ggtatacaat ttaaaaattt ttttaaaaca gaaatagttt cttgctcaaa tggcaaatca
      721 ttataatatt ctagtgactg atatgcaaag aatatagatt ttacctcact ttctgaaaat
      781 gcaatcggtg gaagtatacg ctctttaagt acatgatatc caccagccgc tccaactttt
      841 gaatataatg gaaatccaat actctccagc acctgtaaat ctcttagtat agtacgtttt
      901 gatacagaaa attcttctgc taattctcct gctgtaaaac ttctttttgc atttattgtt
      961 atcatcagtt caattaaacg ctcagctctt gacatattta tactcctaat ttaaatatag
     1021 tgacaataat tgtcactatt atatgataag atattcttac atttaaagca ataataatag
     1081 taaagaaaga aagaaaggac tgatacttta tggaaaataa tactattaag gctgatgata
     1141 ttatcaatta ttgtctatca aacttagatg atgttttatt aatgaatagt tggggggaac
     1201 gagcaattta ctacaatcct aatggtattt taaaacgagg agtatatgtt cttaccatta
     1261 aagaaaaaga cagtaatcat gataaaggtt cgttggttag tcgtccaaat gtataccgtg
     1321 tgaatatagg attaaaaaaa gaaactttta ttgaaatgtt tggatatatt ccaaagcgtc
     1381 caggtgtagg tcaaatagtt gatatggatt ttgattttac aaaattggac acaatcatgc
     1441 cacatcctat ctactcatgg atgggatgga tatgcgtcct aagccctact aaaaagacat
     1501 ttgagaactt taaaacttta ataggagaat cttacaattt tgcaaaacaa aaatttaaaa
     1561 agagaaaaaa caagtaaaaa catatgaaaa taatccctaa ataaatcata ataaaaatat
     1621 taaggttaca agataaaaat taatatctta ataacatgca aaaaagcgaa gccaaaaaat
     1681 gtattattta taaggcttcg ctatatctca aataatttat ttcaaatttc aaaactattt
     1741 attctattat ttcttattat ttcctgttat tcctaatcta tcattcatat cttttatcat
     1801 ttttctaaaa ccactaccta tatcatttcc aacatcttca gttccatgaa ctaaatttat
     1861 aaagtcattt tgaccttttt tcatatcttc atcagatacc ttatctaatt tttctattct
     1921 cttatctata tcttttacta atctttcccc ttcagcgatt aggtcatcat tcattttctt
     1981 taactctgta tcttctgttt taccatcttt tttaagagat gttacaaatg attgtatttt
     2041 atctctacta tctttatatg cagcctttac atcacttaga tatttttcat ttcctggata
     2101 ttctttatct ttaaactgat tatttatact ttctggagta tcataaatag aatatctatt
     2161 tagacctgct atataatcat tatagcttgt tgaataataa ttcatatatc cttcattatt
     2221 atttacagat tcattaggat tttttcctgt attttcactt ggtttttcat tatttttagt
     2281 acatgcagtt atacctatag ctaatactag tgctaatcct acaaataaag ttctttttaa
     2341 tttcattttt attaccctcc tagatgtttt atactataaa aaattttaat aattttcttt
     2401 cttaatttag tatttctata tttttatatt ttatttacta aaattaaaca agttataatt
     2461 tatttttttg gaaatcataa tgaataaata attaaataaa aaaattataa ttttattatt
     2521 gatattgatt atcattcata gtataatcta attacttgat attaattttc atttgaagga
     2581 ggttatcttt tatgtcttgt tgtaattcac aattttgttg taaaaataaa attgaatcat
     2641 catatataaa atggctttta gaggttttag gtccagtctt tttaggctct aaacctgctg
     2701 aaataataaa tatttcgttt actgatgtaa atagagagga aaaaattaat gatatttata
     2761 aatatctata taaatgtaag aaaatagatt ttatagttat tgataaagaa aaaaagggat
     2821 taaaaatctt atttgtaaat aaaaaagcat tatcagaaaa attaaaatgt aaaaaaacag
     2881 taaacttttt aaagttttta ggatacaaac aaaatacgaa tgttaatgct tatttagagc
     2941 atttagtaaa taaacttaag agtgatgttt ttcctgatga aataggtatt tttttaggat
     3001 atcctcttaa agatgtgatt ggatttatgg gatatagtaa ttatgaagtt tctatgatta
     3061 aatattggaa agtttatggt gacacaaaac aatccgagga cacatattcg aagtttttac
     3121 ttcaccgtaa gaaaatgaga aaattactag actacataag tgtagataaa atagtaagtt
     3181 gtttttaatt gtatttttgt ataataataa aaatacaccc tcttttacca tacagtttcc
     3241 ataataaata agggtgtatt ttccacttta atattttaaa gtattctaat tttgattgta
     3301 caacatatct ttaatattta ttttcttttg ttgcattcca ttagacatca aaaattcctg
     3361 tgtatcttct aattctttta tatccttgtc cgttatttta gaactaaagt cataccaaga
     3421 atacatttct tttgtttcat ctaaagataa accaacttct ttagatacaa catccatcac
     3481 ttcatccttg ttttcattca tatattttaa agtttcttca tgaaccttca taaatctttt
     3541 tactaattca ggatattttt cagcaaagtc atcacttaca gcagtgacta ttattccact
     3601 tactaatcct tctccattta caatcatttt ggcacctgaa tttatcgttt tcaatgccac
     3661 tggacctgca agcattgcta catcagcact tttactttct aatgcagaag cagcactagg
     3721 aatatccata tttacatatt caacatcatc tatagtatag ccttctttag caagtgtagc
     3781 aatcaacagt tgatgaagta tagtcccttt tggacctaca atttttttac cttttaagtc
     3841 ttttatagat ttaatattat cattattagt tataagcata tatccttttg gtgaacggct
     3901 ataaatattc gtaattttaa gaccaacacc atttgatgca gctattattg cagacgttcc
     3961 tcctaatgca tgtaaaaagt ctagctcacc tgctgctaat gcttgagttt gctctggtcc
     4021 tgttgtcaat tcatggaagt tgacttttat attgtccttt ttaaattcct ttccaaataa
     4081 atcatacttt ttttctaata tactaggaac attaagtggt gattttacat aagttaaatt
     4141 tatttcctta ggtaaactag cctctttttt tgcaggttca tctttcttat catttgttgt
     4201 tgaacatcct acagtcccaa ccaacaccat tattaaagat gtcattactg ctaaaatctt
     4261 tttgtttctt ttaatcaatt aaaactcccc caattccctt aatatttctt ttttcaagtt
     4321 tatataatag tttttagtta aatctctatt atattcatct tcgacactaa attgtttaat
     4381 ccttttattt ttactaaaaa caattatttt ctttgctatt tccatagctt cttcaatatt
     4441 gtgagttaca aatactacac cttttttagt atttttatgg atatttacaa cttctttttg
     4501 catttttctt cttgtgaagt aatctagtgc tgcaaatggt tcgtccatca gcaaaatatc
     4561 gggattgaag gaaagtgctc ttgctatact tactctgtga accattcctc ctgataattc
     4621 atttggatat gagtttttaa acttttcaag cttcatcatt tttaaatact tgtctaaatc
     4681 aactttattt ctattatctt tttcagtatg taaaagtata ttttcactta cattcagcca
     4741 tggcataagt ctactttctt gaaataccat tcctactttt ggagtacact ttttatcatt
     4801 attaaaaaaa tatatgtttc cactagtagc attttcaagc cctgctaaaa ttctaagtag
     4861 cgttgttttc ccacatccac tttcacctaa tataacagtt atctcttcac tagatatatt
     4921 taaagatata ttatcaagaa ctaaatgctc tttattatca actaaatatt tcttatatat
     4981 attctctagc aaaaatccac ttctaaccat ttaaatcaac ctgcttccct ttgctaaatt
     5041 ttgttattat ctttgaaaat agataatctg aaagtatacc taaaaatcca ataacaaaaa
     5101 ttcctaccaa tacaacatca gttctagaca tatcttttcc atcagaaatc aaatatccta
     5161 gtcctgaaga agctgcaata agctctgctc caattatagc cctaaaacta tacccaagcc
     5221 ctaaactaag tccaacaaca atatccagca tagaattagg gattattatt ttataaaaaa
     5281 ttctcttttt agataaatta aaagatttac ctacttctat taatttattg tcacaatttt
     5341 ttataccttt caatgtattt aaaaatattg gaaaaaagga tgccaaaata ataattataa
     5401 ttttagattc ttcacctata ccaaaccata aaataagcat tggcaccaaa gctagtggag
     5461 gtgtacttcg cataaattca aatagtggtt tgaaatattc atacattttt ttatttactc
     5521 caaatacaac tccaagtggt atagccatca atgaacttat taaaaaacct attaatatcc
     5581 ttcttacact ggcataaaca tttaagaaaa tagaaccgtc atatatcatt tttataaaag
     5641 tatctaagac tatttcagga ggaggcagaa tatagctact ccatataccc aaaacacata
     5701 ctatcttcca taaaattaaa attattaaaa aaatataata tcctttaaac cttttatgaa
     5761 ttttctcaaa catataaaac tccttttaac atatctatcc ctgctaccct ttttattttt
     5821 taatatctta aataataatt aagctatatc ataagattta atctatgcca agtcttaatc
     5881 cacctgaact cattctatca gaaggtgtag aatctgtttt taagccagac aatctttcag
     5941 atggttgtat aatgactatt tgtccaggtt caacaaattc catatgataa gattctcctg
     6001 aagtctgacc aataaaagtc ttccatgata gttttgatac tttaggatat ggttctcttc
     6061 cagtccaagc tactaatgca tctgggtcaa cacaacaagg tccttcaaga attagaggat
     6121 taccatctgt tattatagca acatcttgat tttgacctgt tttatttact aaatgtgtag
     6181 taaaaagacc tttttgagat attacccctg aaccaatcaa ttttacactg taatttaatt
     6241 gttcagaaaa tgccaataag ttttcactct caacataaat ggaatcacct gggtcaattg
     6301 atattacatc tacatggtaa gcattttgag ctaggtaaat ttcaccttca ccttcaacca
     6361 ccattattgg catttgttct cctgtcaatg acctctgaac atgacctaat aatgctcttc
     6421 ccaatccacc gccattactt ggacctaaca gcaatttttc aaaattaaaa tttcctttaa
     6481 aggctaccat agcacctttt tttgcaaaaa atttaccact tccccttgct atacacataa
     6541 gctcgtttgt aacatcaaat ttaaacataa tattcactta tattgcttaa tttagcaata
     6601 atccctccta atcatatatt tatatataat tatacagtaa aattacagca tagtctaacc
     6661 tacttcaaat atgaaatttg ttatttatat aaaaaataag aacctgataa taaagcaatt
     6721 taacttttta tcaggctctt atcctattta tctcttagcg ctatgacaac tcttactact
     6781 tgagcatcca gaacaaccac atccacaact gctaccattc ttttttgaat ttttaaccat
     6841 atacattaca gctagtgcca ttaatactac tacaatagct gctataataa atgtagccat
     6901 attcatcact ccttatttat atgaattaat ttttcatata acttaattta cccatttttt
     6961 cttttttcat atttttattt gaataagtta aaactacaaa gactactgct actgctataa
     7021 atatagatat tattgcccca gcaatacttc ctccagtacc taaaactaaa cttccaactt
     7081 gatttataag aagagcaatt atatacgctg ttaaagtttg gaatcctaat gtaatccatg
     7141 tccatttcca tgaacccatt tctcttttta tggctccaat agctgcaaaa caaggtgcac
     7201 aaagcatatt aaatgccata aatgcaaacg cactagctac tgtaaacata cttgcaactg
     7261 aagcaagaag tgttgggtct tgctctgttg catctgatat accaaataaa actccaaatg
     7321 ttccaactac attttcctta gctactagac ctgtaactgt tgctactgat gattgccaat
     7381 ttccaaatcc aagaggagca aatattggtg caactatatt tcctaagcta gctaatatac
     7441 tatctccagc atctaccatt tgtaatgacc aattaaatga ttgtaagaac cagattactc
     7501 cacaagcaac aaatataatt gttcctgctt tgattataaa tgcttttcct ctatcccaca
     7561 tatgtattaa aacacctttt gcacttggaa catgatattg aggtaattcc ataacaaatg
     7621 gagatggttc tcctgcaaat aaactagttt tctttaatat aattccacaa atgattatca
     7681 ttgcaatacc taagaaatac attgatggag ctacccatga agcacctcca aataatgccc
     7741 ctgcaaataa tgctattatt ggaatcttag ctccacatgg aatgaatgta gttaacataa
     7801 tagtcatttt tctatctcta tcattctcta tagtacgagt tgacataact cctggaactc
     7861 cacaacctga acttataagc attggtataa atgattttcc tgaaagacca aacttacgga
     7921 aaattctatc cattataaaa gctacacgtg acatataccc acaatcttct aatattgaca
     7981 ataataagaa taaaagcatg atttgtggta caaatcctag tactgatcca actccaccaa
     8041 ctagaccatc aactacaagt ccttgtaacc actctgctac atttaaagaa gctagaaaat
     8101 tacttacatt gcctttaata atttctccaa acagtacctt atttgtccaa ttagttgcta
     8161 tagtacccaa tgaacttact gctatatagt aaactcccca cattataagt gcaaaaatag
     8221 gtaatgctag tatacgattt gttacaatct tatctatctt atctgataca gtttccttac
     8281 cttttcgatt cttctttatt atacttgaaa ttattgaact aataaattca taacgattgg
     8341 ctgttattat actttcacta tcatcatcca attcatcttc acaatttcta gttatttctt
     8401 caatactatt caatattgtt ttagaaatat caagtttttg tataacattt tcatctctct
     8461 caaatagctt tatagctaac cagcgtgttt ctacatctat atatggagtc ttttcttcta
     8521 ttattttttc aattttttct attgcatcct tactttcatc aacaaaaggt aatttgaaat
     8581 ttaatttatt gttactactt gcaagttcaa ctgccttttc agcagcctcc ataattcctt
     8641 gacctttaac tgctgttact tctaccactg ggcaacctat aacttcagat agttctttaa
     8701 tatttatctt atcaccattc ttatttacaa tatccatcat attaagagct ataatggtcg
     8761 gtatacctag ctctaaaact tgagttgtaa gatataaatt tctctctata tttgatgcgt
     8821 ctacaatatt tattactgca tccggcttat catctagcat aaaattacgt gtaactactt
     8881 cttctaatgt atatggagat aaagaataaa tacctggtaa atctactatt tccacatctt
     8941 tatttccttt taattttcca cctttttttt caactgttac tcctggccag ttaccaacat
     9001 attgcgatga gcctgtaagc ccattgaaca ttgttgtctt accacagtta ggatttccta
     9061 tgagacctat ttttattgac atttccattc cctccattat tatttaaata catcactgtt
     9121 tgtgatacag aaaatcattc tcattatata attacattaa ccctactcta attaatcttt
     9181 attattccac aataattttt tctgcatctg acttacgaat tgatagttca taatctctga
     9241 ctgttacctc aattgggtca ccaagaggag ctacttttct tataaatata ttaacacctc
     9301 ttgtaatccc catatccatt atacgtcttc gtgtagctcc ttctccttct aactttttga
     9361 cttttacagt ctctccacac ttaatatcct tcagtctgtt catgtcatta cctccctata
     9421 ttattattct acttgccatt tttttatcta atgcaactct agtatctttt acgtctatta
     9481 ttaagttacc atctatctta gaaactattt taacatttgt acctactaca aaacctatac
     9541 tatttaaaaa agtcctcgtc ttatcacttc ccgaaatttt ctttataact acttcttcac
     9601 ctgtatttga taatatcaat ggcatcatat aatattcctc ctcttcaacc aatttaaatt
     9661 tacaaacaac ctctatctta tatataaatc acaatttctt aaattttgac tcgttaaaat
     9721 aattacttat ctttttcctt attcttacaa ttcctaattt tgatttaagt ctatcacaat
     9781 agcatatttt ttgcaagtga ttattgtatt cttttgattt tttttctcat ttgatttatt
     9841 gtattaataa aatctataaa aattcatact gctatcctat atattttgag atttctctta
     9901 gatactcata accatattct gcataagaat gttcttttga taaagatatt attctatagt
     9961 aatgattttt ttcttttcaa tgtaatttaa atattaatct aatacaatca taaaaacata
    10021 attaattcta tgattctact gactatctct atctcaaaaa atataatgac actactaata
    10081 ttttttaaca ttagtagtgt cattatgttt ttcaaattga ttaaattttc tatattttat
    10141 aataaaacat attagcctaa acatttagat agaaagtttt tttctttaat attaaaaact
    10201 tctgtttgag cattagaata gttttttgag tatgtatcaa taaaaccatg atttgcgtct
    10261 aaaatttcaa tttgaatatt ttgccttcta gaaagttgag aagaaacata atcaacatcg
    10321 aatgaatcgt attttgcaaa cactagcaaa ataggacatg ttggaattac atccatataa
    10381 tctctaattc gggagccata acaacaaatt ataccatcac acaaagagtt ttcactacat
    10441 ctccatgcaa tagttgcacc tatactatac ccaactacaa atacatgttt atactccgat
    10501 tttaaaccat ttataagttt ttctactttt ttataaatat caaacttaac attatttata
    10561 aaaaaatcat atgcttcttg agcttttaag tatgaaaaaa ctcttttttc tcctaagagt
    10621 tctggacaaa acacatcata cccaccttta taatactttt gacaaacatc ttttataaaa
    10681 ttattaactc cataaatttc atgcagtaca acaatagcta tattactttt atgtatatac
    10741 ttaatcagat tgtccaccac ctgtcgatat tttttacatc tagtttaaat tattttaagt
    10801 atgtcaattt actagctcta aaatttgact tataaaataa tccgtttctt acgataaact
    10861 ttctgcaaag taaaattgac taagtagtaa aaatcagcac tcctgtgcca atgttataca
    10921 agatatgcag tagccatgcc ccccacagac agttagtttt tcgatatact aaatcacatg
    10981 aaaagttaag taatataagg catatcacat aaaatccaga tagaattgca aatgaaaaat
    11041 ctccacttga aatccatttt acagggtaat gtgtagatag aaaaagaaaa gcattaatac
    11101 aagatgaaag tacactattt tttattaatc cagttaacct tgtttgaata taccctctaa
    11161 aaacaatttc ttctgaaata gcagaaacaa taaatgtaac aatcataaaa acagtaggta
    11221 attgaaaatc aacttttttt ccttgcataa ttccagctgt taaaataacg aaaattacga
    11281 gtacagtagc accaataact ccatacaaaa gacttttatt taaatttcac attgtaatcc
    11341 caatcgtatt tagtttttcc ttcgaaagta gtacaaatcc cagccctata agtaaaatca
    11401 agattgacaa tatcatttgt gagttagtta aaattgttga acttaaattt gttgtataca
    11461 aataaccttg gaaaaataat agtaacatag atatcaaata aataaatatt gcttttactc
    11521 catcactttt agaataattc ttacataata aaacatattc tttatcttca aatacagttt
    11581 taaacactat aaatactcct ttctaattaa attcttattt atttctcata ttttatcata
    11641 aatatatgtt taaatcaaat taattctatt tattacataa atcagagata ataaaactaa
    11701 aaaattaatt tcattaaaac tatatttata atgatttaaa tatttacaag attatagcta
    11761 taaaaaatat aaaatacaac tattaaaaag gagcatatca ttataatttt aaaaatcata
    11821 aatgatatac tcctaaaaat ctacttaact tatattaaat ttattttcca aaatatctat
    11881 ttaataatcc taagaatgct ttaccatgtc tagcttcatc tttacacatt tcatgtactg
    11941 tatcgtgtat agcatctagt cctaattctt tagctttttt agctaatttt aattttccat
    12001 cagttgcacc atactcagca tcaactctaa ctcttaagtt ttcttttgta tctgcaacta
    12061 caacttctcc aagaagttct gcaaatttag cagcatgttc agcttcttca agagctattc
    12121 tcttataagc ttctcctact tctggataac cttctctatc agcttgtcta ctcattgcta
    12181 aatacattcc tacttctgta cactcaccaa caaagttagc tcttaatcct tcgattattt
    12241 cttcatctac accttgagct actcctattc tgtgctcatc agcccaattt ttttcgcctt
    12301 tcatttcttc aaatttatca gctccaactt tacatactgg acattgtgct ggtgcagcat
    12361 ctccttcatg tatatatcca catactgtac aaacaaattt cttcataatt actttcctcc
    12421 taaattttat atatcaaatt aaatttttta tttattaagt tagtctatat atacccgcac
    12481 catatacctt taaacaattt ttttaaagtt ttttctaaat acttattttc cctgtgtcaa
    12541 taatatgttt ctataataat gtccttttaa ttttatcaat tctttatgat ttcctgattc
    12601 cacaattcta ccattttcta aaactattat attatcacaa tttgatatgg tacttaatct
    12661 atgagctata attatacttg tctttccata agttaaatta tttattgctt cttgaatttt
    12721 agcttctgtt gctatatcta tgttacttgt agcctcatcc aaaataagta ttggagcatt
    12781 ttttaatact gctctagcaa tacttattaa ttgtttttga ccttcactta aatcttcacc
    12841 cctatccgat aatacagtac tatatccttc acgcatttta actataaatt tatgtgcatt
    12901 tgctatttta ctagcatata taacttcttc atcagtagcc tccagatttc cataccttat
    12961 attttccata actgtatcat tgaatatata accttcttgt ggaactactc caaaacaagt
    13021 tctcaaatag tttctgttaa tagagtatat atccttacca tctaaaaata tacttccttc
    13081 atctatatga taaaaatttg taattagatt tataattgtt gtttttccac ttcccgtctc
    13141 tcctatgatg gcatttgatg tgccagcttt gatttttagg tttatattat ctaaaatttt
    13201 cttttttgaa tcataagaaa aacttacatc tttaagctca atttctccct ttacaaaatg
    13261 agagtttaaa ttaccatttt tattatcgtt aatctcactt ttaaacacgt tatccacttc
    13321 ttgttcttct tgttcatcta taatttcaaa aactctttca catccagcta tggctgaaag
    13381 taatgtatta aatagatttg ctaattcatt taaaggtctt gtaaattgtc ttacataact
    13441 taaaaaacta gctataaccc ctatggttat aatatcttta gatgcaagaa cacctcctat
    13501 aatacatata gttgcaaatc ctatattact aatcacattc ataataggca ttaaaagaga
    13561 agtgtaaatt tgcgatttaa gggaaatatt tagaagtcta tcattgactt ctttaaaatc
    13621 atttacagat tttctttcat aattaaaaga ttttactaca tttatgtttg atatcatttc
    13681 ttcaatatgt gcatttagtt ttcccaactc aacttgttgt tgcttaaaaa aaactctagt
    13741 tctctttgca ataaaattac tcacaaacat tactatcggt attaatatta cactgcaaaa
    13801 tgttaaaatt gggcttaata caaacatcat aataaaagtc atcaatatgt ttaagattcc
    13861 tgtaattaac tgtactaatg aatttgatat tcctgtactg atattatcaa catcatttgt
    13921 cactctactc ataatatctc cagtagaact tttatcaaaa aaggttattg gtagattttt
    13981 aaattttaaa aataaattac ttctcatttc tttgactata ctttgagata atctagctgt
    14041 acatatcccc ttagacagtt taactgaaaa ctcaattata taaaatgaaa gtaaaataat
    14101 tattcctttt aagaaaatgg attttgaata agtatcgata tctattatgt caactacctt
    14161 tccaatagta tatggtatta cagttgatat aattgaatca attattacta gcaaaaaaat
    14221 aaatctagta atcttcttat cttttttaaa gtacataaaa attcttttaa acgttttttt
    14281 aaaatcttta ggcttttctt ttttctttaa tctactgacc ttttgatttc cagtacttaa
    14341 gttcaatata cttcctcctt aatttacatc ttcacttact aaattctgca acgcaaaaat
    14401 ttttttataa attggagaac taaccagtaa atcttcatgt gtagcaaatc caaccacctc
    14461 accctcatcc aagactaaaa tcttatcaca gtcaattata gaactaatct tttgtgaaat
    14521 agttattaca gtacatttct tactttcctt ttctcttaaa ttacttatat actcttttat
    14581 attctttctt ataattgtct ctgtattaat atccattgca ctaaaacaat catcaagaat
    14641 taatatttgt ggttttttgg ctatagctct agctatagta attctttgtc tctgtcctcc
    14701 tgataaattt ttaccccttt gaaataaaac ctcatcataa gaattttcga gtttagttat
    14761 aaattgattt gcatttgcta tctcacatga ttttataaca tcttctctac ttataccctc
    14821 atttcccata actatatttt ctagtatact ttttccaaac acactgctat tttgaaatac
    14881 tacacctatt ttttccctta aactttcttc agaaatactg tatatactac gtcctccaat
    14941 cttaatatca cctttatcaa ttatatataa tttttgaatt aaatttacta aagaagtctt
    15001 tcctgaacca gtttgaccaa tcacaccaat attttgacct tcttctattt taaaggatac
    15061 gttttttaat attttttcat ctgtattttt gttatacgaa aaatctacat tttcaaaaat
    15121 tatatcacaa tttacaaact ttaaatcttt ttctccaaca tctaaacttt cttctctctc
    15181 aattacttct tcattctcat caaccaaaac ctcacttatt ctctcataag atgcttttgc
    15241 cctaacaaaa acattaaaaa catgtgaaat cattataaga gatgttaata ttctagtcat
    15301 atagtttaca taagcaacta taatcccaat tttaatttct cctgaataaa ttaaatgcct
    15361 tccaatcagt aatattatta ttatggaaac attaatgatt attgtaattg tcggtctaaa
    15421 aaatgacatc atagttgtag cttttctact atttttaaaa agttcatcat ttaactcttc
    15481 aaagctttgg ttctcataat cgtatctaca aaatagttta actactttta ttccacttaa
    15541 aaactgtctt aattttgaat ttactttatc tgtactttct tgtacatttt taaataatct
    15601 ataccctatc ttcatattaa gcaatattat aataaatata attaaaactg caattagaat
    15661 aattattgac atctttaaat ttaattttat agctataatt aaacttccta tacacattat
    15721 tggtgacttt ataaaaactc tcatcattcc attaacgaat tgttgcattt gattgatatc
    15781 attagtaatt cttgttatta acgaagctct accaaattta tctatttgtt ttaatgagta
    15841 tgtatttatc ttttcaaata catcctgtct taaatcataa gaaaaatgct gagaaactct
    15901 tgccgagatt acacttctta ttattgcaaa tactgcacct aaaaaagtta tacctatcat
    15961 tatagctcct gttgatagta tgtagtctag gttcttattt gaaaccccta tatctattat
    16021 ttttgccatt atagttggtt gagctaaatc acaaaaagct tccaatgtta aaaaaaatac
    16081 tgctgttaga aataatacta tatatttttt tatgtatttt ttaaaatact tcattcaatc
    16141 atcccttcat agaattttct cattaccaaa agtatatcat aatggctaat ttaattgatt
    16201 atatcaatta taaatatttg atttattatt aatttttata ccatatattt tataaattat
    16261 ttgtttttat ttcctat
//
LOCUS       DACTZW010000092        16091 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.092, whole genome shotgun sequence.
ACCESSION   DACTZW010000092 DACTZW010000000
VERSION     DACTZW010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16091
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.092"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(128..862)
                     /locus_tag="JAM15_15765"
     CDS             complement(128..862)
                     /locus_tag="JAM15_15765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine biosynthesis protein TtcA"
                     /protein_id="HAT6799706.1"
                     /translation="MSIQKLLSKARKAIQDFDMIQENDKIAVGLSGGKDSLTLLHILK
                     SYQRFSPQNFELIAITLNTGGVDNSPLDKLCKEINVPFYEFQTDIKEIVFDIRQEKNP
                     CALCANLRRGALNDNAKKLGCNKVALGHHKDDAIETFLMSMFYEGRVNCFSPKTYLDR
                     QDLTVIRPMIYIEEYMTKKISKDSNYPIITNPCPANGHTRREYIKNLIANLNKEMPDF
                     KRNVFGALNNSEKLFIWDKEKIKNFK"
     gene            988..1704
                     /locus_tag="JAM15_15770"
     CDS             988..1704
                     /locus_tag="JAM15_15770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HAT6799707.1"
                     /translation="MKKFKLIGAIILVVFISVFISKDRLLKKDKDPIVAAQHDSEQDV
                     EVNSQNKNHSNSISNILLVNKTNGISKNYTPENITKVNIPFVEEATEEEKQMAGEPAK
                     AVEDLVKQANSEGIQFLGSSAYRSYDTQLDTYTRRVKSQGREKADAYVAKPGYSEHQT
                     GLCIDLTNPERWFVGSTKEAKWLAENAHKFGFIIRYPEGKEDITGTAYEPWHIRYVGK
                     DAAEEIYSKGLTLEEYLQNK"
     gene            1838..2530
                     /locus_tag="JAM15_15775"
     CDS             1838..2530
                     /locus_tag="JAM15_15775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010296823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6799708.1"
                     /translation="MNNTVLVVDDEKEIRDLIEIYLLNSGYNVIKAEDGKEALDILKN
                     ENIHLMILDIMMPKMDGIEVCRKVRESLNIPILMLSAKSEDMDKIQGIMTGADDYLTK
                     PFNPLELTVRVKSLIRRAYYFSGANNEDKDVIKVGVVIIDKEKHSVTVAGNEIILTSR
                     EFDILYLLANNKGRVYSTEEIFEKVWKEKYYQSNNTVMVHMSRIRDKIEKYTDGEKII
                     HTVWGVGYKIEK"
     gene            2520..3701
                     /locus_tag="JAM15_15780"
     CDS             2520..3701
                     /locus_tag="JAM15_15780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HAT6799709.1"
                     /translation="MKNKSLLNHMFRPILDLIISCALTSMLILTSMYIIKSLYFNSEI
                     SVINQLVYQLRDFRSLIGESLFYPFLFTITSLAIYSMISYKRNKQIVDFIRKTNRKNQ
                     KLEIIKSAVNLMDEGNLEKSIDIEYDLDILKDKEKDDIDELAHKINNIVHQLRNITIE
                     ERQAQQTKTDLITNVSHDLRTPLTSIMGYLGVIEEGKYKDEVQMMYYVDIAYEKSKNL
                     NVLINDLFELTKMQNNTIKLNKIEINLVELLSQVVSQFEIYFKQEFMVSRINFNEEKL
                     IVKADPNKLVRAFENLITNAVKYGKDGHYVDIVTEKMEDMAVVKVINYGEPIPVLDLP
                     NIFDRFYRVEKSRNRNVGGSGLGLAITKNIVNLHDGEITVSSDKYQTVFEVQLPIIQS
                     A"
     gene            3983..4438
                     /locus_tag="JAM15_15785"
     CDS             3983..4438
                     /locus_tag="JAM15_15785"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012423319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HAT6799710.1"
                     /translation="MEKVESFKLDHTKVKAPFVRKCSVLDGVKGDKVTKFDLRFLQPN
                     VESFGTAAMHGLEHLLATYLRDTLDGVIDLSPMGCRTGFYLILWGDVDAKTVKIGLEE
                     ALKKVLESDKMPAATAIECGNYRDLSLFGAKEYAKDVLDKGFSLNIYGE"
     gene            4428..5153
                     /locus_tag="JAM15_15790"
     CDS             4428..5153
                     /locus_tag="JAM15_15790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Vitamin B12 dependent methionine synthase,
                     activation domain protein"
                     /protein_id="HAT6799711.1"
                     /translation="MENNLIGREDISINQSEVLRYLQYRGQEIDKDLKYTIDECVAIT
                     KNKINPRYLSRIYPIRINKDNVVELEGTNLTLESKDVYELLKECNECVIMAATIGIDI
                     EKEIRRHSYSNLTKGLIIDSCGTTAIEEVCDIVQNNLEKVFLKQDKFITMRYSPGYGD
                     LPIEKNIDILNVLNAQKQIGLTITSNGIMIPRKSVVAIIGISNTRINKSKKEKSCENC
                     KNYRNCTYRKGANSCGNKTISEK"
     gene            5125..7506
                     /locus_tag="JAM15_15795"
     CDS             5125..7506
                     /locus_tag="JAM15_15795"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HAT6799712.1"
                     /translation="MEIRQYLKNNILIFDGAMGTMLQQKGLKLGENPEVFGLQNPDKL
                     IEIHTAYLEAGSNVILTNTFGCNELKLDSKYTVEEVIDNAVLVAKKAIENVDNTKPRY
                     VALDIGPIGEMLEPMGTLSFDNAYEIFKRQVLQGVKSGVDVIVIETMMDLYEAKVAVL
                     AAKENSDLPIFCTMTFDEGGRSFTGCMPECMVATIEGLGVDAIGVNCSLGPKQLLPIV
                     EKIASRATVPVMVQANAGLPNIVDGEAIYDVDAKEFFEGVKKFVEVGATIIGGCCGTN
                     PSFIKEISENINSVTKGCIEKIDKCVVCSPSKFVEVQSPTVVGERLNPTGRKSLQEAL
                     KNENVDYAISLGLEQVNAGAQILGVNVGLPEIDEKKLMPKLIREIQAVVDTPLQVDSS
                     NVEALEQGLRYYNGRTIVNSVNGKEESLESILPIVKKYGSCVVGLTLDEKGIPKKAEE
                     RFEIAKRIVNRAVSYGIKPKDIFIDCLSLTVSAQQEEAIETIKAITMVKTLGVKTILG
                     VSNISFGLPNRKALNASFLTLALGAGLDLAIINPNEYSMMEAINSFKILNNTDKGCIN
                     YINQYSNINNSKKSDSSTKIDKDLPLDILVERGLKDEAKNITLNLLKEKDENYILDEI
                     LIPALDKVGKRYDSGDIFLPQLIQSAETVKVSLNTIKETLLNKSSNNVSKGKIIVATV
                     KGDIHDIGKNIVKIMLENYGYEVIDLGKDVPIEEVVEVAKKRNIKLVGLSALMTTTVQ
                     SMKDTIQALRDNEINAKVFVGGAVLTEEYAEEMGADYYSKDAKSAVEIAKLNF"
     gene            complement(7711..8940)
                     /locus_tag="JAM15_15800"
     CDS             complement(7711..8940)
                     /locus_tag="JAM15_15800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HAT6799713.1"
                     /translation="MNLNRNLEKYAELAIKVGVNIQPGQILLIKSPIECADFARNALK
                     EAYKCGAKNVYIEWSDEESTLIKYLYAPDEAFHEFPKWTAEQYVDIAKEGGAFLSVYT
                     QNPDLLKDVDPERVANFQKASGKALKEWRSYTLTDKCKWSIVSVPTKDWAKKVFPNLS
                     EDKAIEKLWDAIFKCSRVDGQDPIKAWEEHNENLKSKMDFLNKNNFKTLKYKSSKTDL
                     TLDLPKGHVWLSGASKDPNGISFNPNIPTEEIFGMPHKFKVNGTVYSTKPLVYGGNII
                     DNFFLTFKDGKIIDFSAEKGLDTLEKLIETDEGSHYLGEVALVPYNSPISNTDIIFYN
                     TLYDENASCHFAIGSAYKTCLEGGNNLKDEELDEHGINDSLTHVDFMIGSADMDIIGE
                     TYGGKQIQIFKNGNWAF"
     gene            9541..10455
                     /locus_tag="JAM15_15805"
     CDS             9541..10455
                     /locus_tag="JAM15_15805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799714.1"
                     /translation="MELYEAIFYRKSVRNFSSKKIKKPLMEEIKRSCKNLEYLNEDLN
                     IKAHVVDRGHIIHFLMGKECKVKAPHYIVVTSDKGEDYLQNIGFATEGVVLRLTTLGI
                     ATCWLEGNLKREDILEFVDIGNKNFEEDDEDDLDYLAGIKTEEDDENKIENPYIIIAF
                     GYPAKNEELFRTRYARPDRKPVKDMINKINRNRKWKDILELTRRAPSVKNSQPWYFHK
                     DERGLHLFEKRPKKHCEDMNKVSLGVALRHFDIACIKNKIDVSYEKLPIRNKIGKSYF
                     ITVVEHVKPEEETQEENVTLEKEESQDE"
     gene            10479..11114
                     /locus_tag="JAM15_15810"
     CDS             10479..11114
                     /locus_tag="JAM15_15810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1847 domain-containing protein"
                     /protein_id="HAT6799715.1"
                     /translation="MYKCGKCNLRGCSNGNMDKLMKICPTREIELQQKAKQLYEEEEN
                     RKIAYNAGLVEAEGYCQYTRLKEIIEFAKKCGYKKIGIAFCIGLKREMQTVQKIFEHH
                     GFEVFSVICKNGAMPKSTIGLEASQTISKCSDEVMCNPIGQALFLNEAKVDLNVILGL
                     CVGHDTLAMKYMEAPITTLVVKDRVTGHNPVAAIYNAESYFEKKLFDKDEE"
     gene            11490..12206
                     /gene="pyrF"
                     /locus_tag="JAM15_15815"
     CDS             11490..12206
                     /gene="pyrF"
                     /locus_tag="JAM15_15815"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HAT6799716.1"
                     /translation="MINGKEKLIVAIDTDEFDKAKELIDRLEDSVDIFKVGLEQYVAT
                     KGKTIDYLKEKGKKIFLDLKFHDIPNTMKSAVRAAVRDNVWLMTIHVSDMEGMRQCAL
                     IAREEAERLNIEKPLVVGVTVLTSLSNQDLQDIGCNMTTEELAIKRAKLAKESGIDGV
                     VCSAQEVDKIVEACGTDFITVCPGIRPKSAEVGDQKRVVTPSDAIKKGAHYLVVGRPI
                     TKAENPRESAINIVREIENA"
     gene            12232..13275
                     /gene="carA"
                     /locus_tag="JAM15_15820"
     CDS             12232..13275
                     /gene="carA"
                     /locus_tag="JAM15_15820"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HAT6799717.1"
                     /translation="MKGKLILEDGTVFEGKAFGYLKEAIGEVVFNTSMAGYGEILTDA
                     TYYGQIVTMTYPLIGNYGINLEDVESNKVQVKGLIVREKSDNPNNFRCEMDIDTYLKQ
                     NKVIGLEGIDTRALTKIIRNNGTKRGIITLENVSLQDVQSKLEEHCNKDSVKNVTRKE
                     IENIKGTGAKVVVIDFGVKNSVLESLKACNCDITIAPAMTTVEEILNINPDLILLSNG
                     PGNPEDINDIVENIKKLIGKKPLTGIGLGHQILALALGGKTSKLVFGHRGGNHPVKCL
                     ETGKVFITSQNHGYNVSEMPENTEVTHINLNDNTIEGMRHKELPIYSVQYIPEYTTKE
                     DLDCIFNKFLALI"
     gene            13328..>16091
                     /gene="carB"
                     /locus_tag="JAM15_15825"
     CDS             13328..>16091
                     /gene="carB"
                     /locus_tag="JAM15_15825"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002844223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HAT6799718.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQSLKEEGIEV
                     VLINSNPATIMTDKEVADKIYIEPLTIEFIEKIIEKERPDSLLAGMGGQTGLNLAVEL
                     YEKGILDKYGVKIIGTSVESIKKGEDRDIFREVMKEINQPVIVSDIVTDLQAGLDYAL
                     TIGYPVVVRPAYTLGGTGGGIADNEEELREILSHGLQLSPVGQVLIEKSIKGWKEIEY
                     EVIRDSKGNCIVVCNMENIDPVGVHTGDSIVVAPTQTLSNKECAMLKKASLDILNAVE
                     VQGGCNVQFALNPHSFEYAVIEINPRVSRSSALASKATGYPIAKVSSKIALGYTLDEI
                     ENAVTKKTYACFEPTIDYVVAKIPKWPFDKFKKANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHTPSEERSIEELKKRVVVPDDERLFDLAEMIRRGYKVEMIEQ
                     ITGIDKWFINKFKWIVEQEEKLKVMKIEDLTKDYLLELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIKPAYKMVDTCAGEIDAISPYYYSTYEQYDEVVVSDKKKVIVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMDIETIIINNNPETVSTDFDTSDKLYFEPLTEEEVLSI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFDDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWSLNEGIEVANELGYPVLVRPSYVLGGQGMEITYNEEKLSQYLQDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGDSTTMYPSQNISDE
                     IKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNPRASRTVPYISKVSGVPIV
                     DLATKCMLGAKLKDLGYGTGVYKEPKLVSVKVPVFSMSKLSKVEVSLGPEMKSTGEVL
                     GVGENLE"
BASE COUNT         6480 a         1773 c         2911 g         4927 t
ORIGIN      
        1 taagaactat taaaatatag attaaagata ataacatata ataaataaaa aagtaagatt
       61 gtgtagatta tataaagatt atttacaatt aatacaatct tgctttttta tttaaaaatt
      121 ttaattatta tttaaaattt tttatcttct ctttatccca tataaacaat ttctcagaat
      181 tatttaaagc gccaaataca tttcttttaa aatcaggcat ctctttattt aaattagcaa
      241 taagattttt tatgtactct ctcctagtat gaccatttgc agggcaggga tttgtgataa
      301 taggatagtt agaatctttt gaaattttct tagtcatata ctcttctatg taaatcatag
      361 gtcttataac tgttaaatcc tgtctgtcta ggtatgtctt tggggaaaaa caatttactc
      421 taccctcata aaacatagac attaaaaatg tctcaattgc atcatcttta tgatgaccaa
      481 gagccacttt attacatcca agttttttag cattatcgtt caaagcacct cttcttaaat
      541 tagcacataa tgcacaagga ttcttttctt gtcttatatc aaatacaatt tcttttatgt
      601 cagtttgaaa ttcataaaaa ggaacattta tttctttaca caatttatct agtggagaat
      661 tatcaacacc tccagtattt aatgttatgg ctatcaattc aaagttttgt ggagaaaatc
      721 tttgataact tttaagtata tgaagtagag ttaaactatc ttttccacca gaaagtccaa
      781 ccgcaatttt atcattttct tgtatcatat caaaatcttg tatagcctta cgagctttac
      841 ttagaagttt ttgtatagac attttatcac catcctttaa aaatattaaa tttaagattt
      901 atttaagatt tacttataaa atacttaagt cttatactct aaaattaaca ttatagacaa
      961 acataacaaa aaggagaaga tttaattatg aaaaaattta aattaatagg agccattatt
     1021 ttagtagtat ttataagtgt atttatatct aaagatagat tacttaagaa agataaagat
     1081 ccaatagtag ctgctcaaca tgattcagaa caagatgttg aggtaaattc tcaaaataaa
     1141 aatcactcaa atagtatatc aaatatatta ttggtaaaca agacaaatgg aattagcaaa
     1201 aactatactc ctgaaaatat tactaaggta aacatacctt ttgttgaaga agcaacagag
     1261 gaagaaaaac aaatggcagg agaacctgca aaggcagttg aagatttagt taagcaagct
     1321 aattcagaag gaatacagtt tttagggtct tcagcataca gatcttatga tactcaactg
     1381 gatacttata caagaagggt aaaatctcag gggcgagaaa aggcagatgc atatgtagca
     1441 aagcctggtt acagtgagca ccaaactgga ctttgtattg atttaacaaa tccagaaaga
     1501 tggtttgttg gaagtacaaa agaagctaaa tggttggcag aaaatgctca caagtttgga
     1561 tttataataa gatatcctga aggtaaagaa gatataacag gtacagcata tgaaccatgg
     1621 catattagat atgttggtaa ggatgccgcc gaggaaattt attcaaaagg attaacttta
     1681 gaagaatatt tacaaaataa ataatataaa tgtgtaaata atttgtatta tattggaaat
     1741 ttagaaatga ataaatttat agattacact aactaaaata tagtataatt ttatatgaat
     1801 aaagctatat acaaagatta agttaggatg tgtaaaaatg aataatacag ttcttgttgt
     1861 ggatgatgaa aaggaaataa gagaccttat agagatatat cttttaaata gtggatataa
     1921 tgtaattaaa gctgaagatg gaaaagaggc tctagatatt ttaaaaaatg aaaatattca
     1981 tttaatgata ttggatataa tgatgcctaa aatggatggg atagaagttt gtagaaaagt
     2041 tagagaaagt ttgaatatac caatacttat gttaagtgca aaatcagaag acatggataa
     2101 aatacaaggg ataatgactg gtgcagatga ttatttgaca aaaccattta acccacttga
     2161 acttactgtg agagtgaaat cactgattag aagagcatat tattttagtg gtgctaataa
     2221 tgaagataaa gatgtcataa aggttggagt agtaattata gataaggaaa aacatagtgt
     2281 aacagtggct ggaaatgaaa taattttgac atcaagagaa tttgatatat tatatttact
     2341 agcaaataat aaaggcagag tatatagtac agaagaaata tttgaaaagg tatggaaaga
     2401 gaaatattac caatctaata atactgtaat ggttcatatg agcagaataa gggataaaat
     2461 tgaaaaatat acagatggag aaaaaataat tcatactgta tggggagtag gatataaaat
     2521 tgaaaaataa aagtttatta aatcatatgt ttcgacccat attagatctt ataataagct
     2581 gtgctttaac ttcaatgctt attttaacaa gtatgtatat aataaaatca ttatatttca
     2641 atagtgagat atctgtaatt aatcaacttg tatatcagtt aagagatttc agaagtctta
     2701 taggggagag tttattttat ccatttttat ttacaatcac atcattagca atttattcca
     2761 tgatatcgta caagagaaat aagcaaattg tagattttat aagaaagact aatagaaaaa
     2821 atcaaaaatt agaaatcatt aaaagtgctg taaatttaat ggatgaaggt aacttagaaa
     2881 aaagtataga tattgagtat gatttagata tattaaagga taaagaaaag gatgatattg
     2941 atgaactagc acataaaatc aataatatag tccatcaact tagaaatata actattgaag
     3001 agagacaagc tcagcagaca aaaacagatt taataacaaa tgtgtcacat gacttaagaa
     3061 cacctttgac atccataatg ggttatttag gagtgataga agaaggtaag tataaagatg
     3121 aagttcagat gatgtattat gttgatattg catatgaaaa atcgaaaaat ttaaatgttc
     3181 ttataaatga tttgttcgaa ttgactaaaa tgcaaaataa tacaataaaa ctaaacaaaa
     3241 tagaaataaa tttagtagag ttattaagtc aagtagtatc tcaatttgaa atttatttta
     3301 aacaagaatt tatggttagt agaattaatt ttaatgaaga aaaattaatt gtgaaagctg
     3361 atccaaataa attggtaaga gcatttgaaa atcttataac taatgctgtg aaatatggaa
     3421 aagatgggca ttatgtagat atagtcacag agaaaatgga agatatggcg gttgtaaaag
     3481 tgataaatta tggagaacca attccagtgt tagatttacc aaatatattt gatagatttt
     3541 atagagttga aaaatcgaga aatagaaatg ttggaggttc tggattgggt cttgcgatta
     3601 caaaaaatat tgtaaattta catgatggag aaattactgt ttcaagcgat aaatatcaaa
     3661 ctgtgtttga ggtacaactg ccaataatac aatcagctta gttataaaat aaaagtatga
     3721 ttatgtgata taaatattat aacaataaag tgtttacaaa aataaaaaag taatatataa
     3781 tttaagtcag tttaataaga tacttatcaa gagttagggg agagagttag ctcagtgatc
     3841 ctataccaac cttttatcag gtggtcctgc taacaacgat gagatgactt gaaataatat
     3901 actcttctta tcaataatag ataggaagag ttttttttag aattaatgta acaaatttta
     3961 aagtataatg gaggattaaa taatggaaaa agtagaaagt tttaagctag accatacaaa
     4021 agtaaaagct ccttttgtaa gaaagtgtag tgtacttgat ggagtaaagg gagataaagt
     4081 aactaaattt gacttgagat ttttacagcc aaatgtagaa agttttggaa ctgctgctat
     4141 gcacggttta gagcatcttt tagctactta tttaagagat acattagatg gtgtaataga
     4201 cttatctcca atgggatgta gaacaggatt ttatttaata ctatggggag atgtagatgc
     4261 caaaacagtt aagattggtt tagaagaagc attaaaaaaa gttcttgaat cagataaaat
     4321 gccagcagct acagccatag aatgtggaaa ctacagagac ttatctttat ttggggcaaa
     4381 ggaatatgcg aaagatgttt tagataaagg attttcttta aatatatatg gagaataatt
     4441 taattggaag agaagatata agcataaatc aaagtgaagt tttaagatat ttacaataca
     4501 gaggtcaaga gatagataaa gaccttaaat atactattga tgaatgtgta gctataacta
     4561 aaaataaaat aaatcctaga tatttatcta ggatttatcc tattagaata aataaagata
     4621 atgttgtaga attagaggga acaaatttaa cattagagag taaagatgta tatgaacttt
     4681 taaaagaatg taatgagtgt gtaattatgg cagctactat agggatagat atagaaaaag
     4741 aaataagacg acactcttat tcaaatttaa caaaaggact aataattgat tcatgtggaa
     4801 caacagcaat agaagaagtg tgtgacattg ttcaaaataa tttagaaaag gtttttttaa
     4861 agcaagataa atttataact atgcgatata gcccaggata tggagattta ccaatagaaa
     4921 aaaatataga tatattaaac gttttgaatg ctcaaaaaca aataggtcta acaattactt
     4981 ctaatggaat tatgataccg agaaagtcag tagtggctat tataggtatt tctaatacaa
     5041 gaataaataa atctaagaaa gaaaagtcgt gtgaaaattg taaaaactat agaaactgta
     5101 catatagaaa aggagcgaac tcttgtggaa ataagacaat atctgaaaaa taatatatta
     5161 atatttgatg gtgcaatggg aacaatgctt caacaaaaag ggttaaagtt aggtgaaaat
     5221 ccagaagtat ttggtcttca aaatccagat aaacttatag aaatacatac agcatactta
     5281 gaggcaggtt cgaatgtaat tcttacaaat acttttggat gtaatgaact aaaattagat
     5341 agtaagtata ctgtagaaga agtgattgac aatgctgttt tggtggctaa aaaagctata
     5401 gaaaatgtag ataatactaa accaagatat gtagctttag atattggtcc tataggagaa
     5461 atgctagagc ctatgggtac tttaagtttt gataatgcat atgaaatatt taaaagacaa
     5521 gtactacaag gcgttaaatc tggagttgat gtaatagtaa tagagactat gatggattta
     5581 tatgaagcta aagtagctgt attagcagca aaagaaaact ctgatttacc tattttctgt
     5641 actatgacat ttgatgaagg tggaagaagt tttactggat gtatgccaga atgtatggtg
     5701 gctactatag aaggtctagg tgtagatgca ataggagtta attgttcatt aggacctaaa
     5761 caacttttac caatagttga aaaaatagca tcaagagcta cagtccctgt tatggttcaa
     5821 gcaaatgcag gtcttccaaa tatagttgat ggagaggcta tatatgatgt tgatgcaaaa
     5881 gaattttttg aaggggttaa aaagttcgtt gaagttggtg ctactataat aggtggatgt
     5941 tgtggtacga atccaagttt tataaaagaa atatctgaga atataaattc tgttacaaag
     6001 ggatgtatag agaaaattga taaatgtgta gtctgttcac catcaaaatt tgtggaagta
     6061 caatcgccta cagttgttgg agaaagattg aatcccacag gtagaaaatc tctacaagaa
     6121 gcattaaaaa atgaaaatgt tgattatgct ataagtttag gcttagaaca agtaaatgct
     6181 ggagcacaaa tacttggagt aaatgttggt cttccagaga ttgatgaaaa aaaactaatg
     6241 ccaaaattaa taagagagat tcaagcagta gtagatacac ctttacaagt tgattcttcc
     6301 aatgtagagg ccttagagca aggacttaga tattataatg gtagaacaat agtaaactct
     6361 gtaaatggca aagaggagtc tttagaaagt atattaccaa tagttaaaaa gtatggttca
     6421 tgtgtggttg gacttacact tgatgaaaag gggataccta aaaaggctga agaaagattt
     6481 gaaatagcaa aaaggatagt caatagagca gtttcttatg ggataaaacc aaaagatata
     6541 tttatagact gtttatcatt aactgtttca gcacaacaag aagaagcaat agaaactata
     6601 aaagctataa caatggtaaa gacactagga gtaaaaacta tattaggtgt ttcaaatatt
     6661 tcatttggtc ttccaaatag gaaagcactt aatgcttctt ttctaacatt agctttaggg
     6721 gcagggcttg atttagcaat tataaatcca aatgaatata gtatgatgga agctatcaat
     6781 tcttttaaaa tattaaataa cacagataaa ggatgtataa actatataaa tcaatatagt
     6841 aatataaata attcaaaaaa atcggattca tctacaaaga ttgacaaaga tttgcccttg
     6901 gatattttag ttgaaagagg attaaaagat gaagcaaaaa atataacact gaatctttta
     6961 aaagagaagg atgaaaatta catattagat gagattttaa ttcctgctct tgataaagta
     7021 ggaaaaagat atgatagcgg agatatattt ttaccacaat tgattcaatc agcagaaacg
     7081 gtaaaagttt cattaaatac aataaaggaa actttattaa ataaaagtag caataatgta
     7141 tctaaaggaa aaataatagt tgctacagta aaaggtgata tacatgatat tgggaaaaat
     7201 atagtaaaaa taatgctaga aaattatgga tatgaggtta tagatttagg taaagatgtc
     7261 cctattgaag aagtagtgga agttgctaaa aagagaaata taaaattagt aggattaagt
     7321 gcacttatga ctacgactgt tcaaagtatg aaagatacaa ttcaggcact gagagataat
     7381 gagataaatg caaaggtatt tgtaggaggt gcagttttga cagaagaata cgctgaagaa
     7441 atgggtgctg attattattc aaaggatgca aagtctgctg ttgaaatagc aaagttaaat
     7501 ttttagcata taaattaaaa taaaggtttt actaaatagg atattttata tataatataa
     7561 atataagttt tagatactta tgtttaaaac aataggaatt aatctataat aatgagatta
     7621 attaatataa aaaatattta tcatcaacat taaaaagggc tgggaagtct ggtataactt
     7681 ccatcagccc tttttagtta aaatcatatg ttaaaaagcc caattaccat ttttaaaaat
     7741 ctgtatttgc tttccaccat aagtctcacc aataatatcc atatcagcag aaccaatcat
     7801 aaaatctaca tgtgttaaac tgtcatttat accatgttca tctaattctt catcttttaa
     7861 attgtttcca ccttccagac aagtcttata agcagaacca attgcaaagt ggcaagaagc
     7921 attttcatca tatagagtat tataaaaaat tatatccgta ttggatattg gtgagttgta
     7981 tggaacaaga gcaacttctc ctaaataatg agagccttca tccgtttcaa taagtttttc
     8041 tagtgtatct aatccctttt cagcagagaa atctattatt ttaccatctt taaatgttaa
     8101 gaagaaattg tcaattatgt ttccaccata aacaagaggt tttgtactat aaacagtccc
     8161 atttacttta aacttatgtg gcattccaaa aatctcttca gttggaatat tcggattaaa
     8221 acttattcca ttagggtctt tggatgctcc acttagccaa acatgaccct ttggcaagtc
     8281 tagagtcaaa tcagtttttg aggatttata ttttaaggtt ttaaagttat ttttatttag
     8341 aaagtccatt ttagatttaa gattttcatt atgttcttcc catgctttta tagggtcctg
     8401 accatctact cttgaacatt taaatatagc atcccacagt ttttctattg ctttatcttc
     8461 tgataaattt ggaaacactt tttttgccca atcttttgtt ggcacagaga ctatactcca
     8521 tttacattta tcagttagag tgtaagaacg ccattctttt aaagcttttc cagatgcctt
     8581 ctgaaaattt gcaactcttt cagggtcaac atcttttaat aaatctggat tttgggtata
     8641 gactgataaa aatgccccac cttcttttgc tatatctaca tattgttctg ctgtccattt
     8701 ggggaactca tgaaatgctt catctggagc atataagtat ttaataagag tactttcttc
     8761 atcagaccac tctatataaa catttttagc accacattta tatgcttctt taagtgcatt
     8821 tcttgcaaaa tcagcacatt ctattggtga ttttataagt agaatttgac ctggctgtat
     8881 gttaactcca acttttattg ctaattcagc gtatttttct aaatttctat ttaaattcat
     8941 atttatcctc ctatattttt aatattgaat aacttataaa gtattataac attacttatg
     9001 tttttaatat tgaacaactt ataaaatatt ataactttac ttagattttg ggtcatattc
     9061 aaaatattta tactttatag attgagaaat aaaaaaaata ttttaattaa aacagattat
     9121 gaggataaca aacttattta agcagtatgt tttttgttga taataatatt aaagtagaaa
     9181 taaaaatact tttttagtga aaagctatac aagaataccg aaaaaaactt ataatataat
     9241 aatgagatag atatttataa atgaaaaaaa atttttctgg caaagcttaa ttaaaaaggt
     9301 aatagctagt gttgttattt aaattagcat agaaaatcaa ataaaaaaat tatgctaatg
     9361 tatagacatt gataaggtag aatttaagcc ttttgaatgc tatattaaac tagagtagat
     9421 attcttatga atttcaaaat agggcaggag gaaaaaggaa ataaaactat aaaaaatata
     9481 aagtatttat ataaatttat agagtttata cgtcagaaga tttcagttag gagggcataa
     9541 atggagcttt atgaagccat tttttataga aaatctgtaa gaaatttttc cagtaagaag
     9601 ataaaaaagc cattgatgga agaaataaaa agaagttgta aaaatttaga atacttaaat
     9661 gaagatttaa atattaaagc acatgttgtt gatagaggtc atataataca ttttttgatg
     9721 ggtaaggaat gtaaagtaaa ggcacctcat tatatagtag ttacatcaga caaaggtgag
     9781 gactatttac agaatatagg atttgctaca gaaggtgtag ttttgcgcct tacaacattg
     9841 ggaatagcta cttgctggtt ggaaggaaac ttaaagagag aagatatctt ggaatttgta
     9901 gatattggga ataagaattt tgaagaagat gatgaagatg atttagatta tctagctgga
     9961 ataaaaacag aagaagatga tgaaaacaaa atagaaaatc cttatataat aatagcattt
    10021 ggatatccag caaaaaatga agagttgttt aggacgagat atgctagacc tgatagaaag
    10081 ccagtaaaag atatgataaa taagataaat aggaatagaa agtggaaaga tatcttagaa
    10141 ttgacaagaa gagctccatc tgtaaaaaat tctcaaccgt ggtatttcca taaggatgaa
    10201 cgaggtcttc atttatttga aaagagacct aagaaacact gtgaagatat gaataaggtt
    10261 agcttaggtg tagccttaag acattttgat atagcttgta taaaaaataa aatagatgtt
    10321 tcatatgaaa aacttcctat aaggaataaa ataggaaaat catattttat aactgtagtc
    10381 gagcatgtga aaccagaaga agaaacccaa gaagaaaatg taactctaga aaaagaagaa
    10441 tcacaagatg aataaaattt tggaagggga tattggatat gtataagtgt ggaaaatgta
    10501 atcttagagg ctgttctaat ggaaatatgg ataaattaat gaagatatgt ccaactagag
    10561 aaattgaact acaacaaaaa gcaaagcaac tttatgaaga agaagagaat agaaaaatag
    10621 cttataatgc tggattagtt gaagcagagg ggtattgtca atatactaga ctaaaagaga
    10681 ttatagagtt tgctaaaaag tgtggttata aaaagattgg catagcattt tgtattggac
    10741 taaaaagaga aatgcaaaca gtgcaaaaaa tatttgaaca tcatgggttt gaagtatttt
    10801 ctgttatatg taaaaatggg gcaatgccta agagtacaat tgggctagaa gcatctcaaa
    10861 caatatcaaa gtgttcagat gaggtaatgt gcaatccaat aggacaagct ttatttttaa
    10921 atgaagctaa ggttgacctt aatgtaattc ttggattatg tgttggtcac gatactttag
    10981 ccatgaaata tatggaagct cctataacaa ctttagttgt caaagataga gtaactgggc
    11041 ataatccagt tgctgcaata tataatgcag aatcatattt tgagaaaaaa ttgtttgata
    11101 aagatgaaga ataattcaaa gacttattga cataaaaagc aattagtggt ttaattataa
    11161 aaaagataaa actttaaatt atcctataga tacataaagt tatataaata aagaaagata
    11221 ttacagctaa attccttaaa gtagtccaga gagactaaag ggttatagat aatgttagta
    11281 tataacctct agtaaatctt ctagaggttt ttgatgagta taaaataaaa atttaaatat
    11341 aataaagtct tttaaactag tccagagaga ctgggaaaga tatctcatag ctaatgaata
    11401 gagttatgta tagataaaat ccttatgcct cttttggtgt gaggattttt ttatgattat
    11461 ttaggcttta ttaaaaagga gatgtaaaaa tgataaatgg taaagaaaaa ttgatagttg
    11521 caattgatac tgacgaattt gataaagcta aagaactaat agacagatta gaagatagtg
    11581 tagacatatt taaggtaggg ctagagcaat acgttgccac aaaaggtaaa acaatagatt
    11641 atcttaaaga aaaagggaaa aaaatatttt tagaccttaa attccatgat ataccaaata
    11701 ctatgaaaag tgcagtgaga gctgcagtga gagataatgt ttggttaatg acaatacatg
    11761 tatcagatat ggaaggaatg agacaatgtg cactaattgc tagggaagaa gcagaaagat
    11821 taaatataga aaagccatta gtagttggag taacagtttt aacttcatta agtaaccaag
    11881 atttacagga cataggatgt aatatgacaa cagaagagtt agctataaag agagctaaac
    11941 tggcaaaaga atcaggcata gatggggttg tttgttcagc gcaagaagta gataaaatag
    12001 tagaagcatg tggaactgat tttataacag tttgcccagg aataagacct aaatcagcag
    12061 aggttggaga ccaaaaaaga gttgtaactc catcagatgc aataaaaaaa ggtgctcatt
    12121 atttagttgt tggaagacct ataacaaaag cagaaaatcc aagagaatca gctattaata
    12181 ttgtaagaga aatagaaaat gcttagataa aatatttggg aggtagctta catgaagggg
    12241 aaattaattt tagaagatgg aacagtattt gaaggaaaag catttggata tctaaaggaa
    12301 gctattggag aagttgtatt taatacttca atggctgggt atggagaaat attgacagac
    12361 gcaacttatt atggacaaat agttactatg acttatccac ttataggaaa ctatggaata
    12421 aatttagaag atgttgaatc aaataaggtg caagtaaaag gacttattgt aagagaaaaa
    12481 agtgataacc caaataattt tagatgtgaa atggatatag acacatatct aaagcaaaat
    12541 aaggtaatag gacttgaagg aatagataca agagcattaa ctaaaattat tagaaacaat
    12601 ggaactaaga gaggaattat aactttagaa aatgtatcat tacaagatgt tcagtctaaa
    12661 ttagaagagc attgtaacaa agattcagta aaaaatgtta caagaaaaga aattgaaaat
    12721 ataaaaggta ctggagctaa agttgtagtt atagactttg gtgttaaaaa tagtgtacta
    12781 gagtctctta aagcttgtaa ctgtgatata actatagcac cagcaatgac tacagtagaa
    12841 gaaattttaa atataaatcc tgacttaatc ttattatcta atggaccagg aaatccagag
    12901 gatataaatg atatagttga aaatataaaa aaattaatag gcaaaaagcc attgacagga
    12961 ataggtttag gacatcaaat tttagcattg gcattaggag gaaagacttc aaagcttgta
    13021 tttggacata gaggaggtaa tcacccagtt aaatgtttag aaactggaaa ggtatttata
    13081 acttctcaaa atcatggata taatgtttca gaaatgccag aaaatacaga ggtaactcac
    13141 ataaatttaa atgacaatac tatagaagga atgagacata aggaattacc aatatatagt
    13201 gttcagtaca ttccagaata cacaacaaaa gaagatttag attgtatatt taataaattc
    13261 ttagcattaa tatagattta gtattattta cagatagtaa aaaccattta gataaggaga
    13321 aaaatttatg cctaaattag atagtataaa gaaaacttta gtattagggt caggaccaat
    13381 aataataggt caagctgcag agtttgacta ttcaggaaca caagcttgcc agtctttgaa
    13441 agaggaaggg attgaagttg tattaataaa tagtaatcca gctactataa tgactgataa
    13501 agaagtggca gataaaatat atatagaacc attaacaata gaatttatag aaaaaataat
    13561 agaaaaagaa agaccagaca gtttacttgc aggtatgggt ggacaaacag ggctaaatct
    13621 agcagttgaa ctttatgaaa aaggcatact agataaatat ggagtaaaga taataggtac
    13681 ttcagtagaa tctatcaaaa aaggtgaaga tagagatata tttagagaag taatgaaaga
    13741 aataaatcag cctgtaatag ttagtgatat agttacagat ttacaagcag gtcttgatta
    13801 tgcacttaca attggttatc cagtagttgt aagaccagca tacacactag gtggaactgg
    13861 tgggggtata gctgataatg aggaagaatt aagagaaata ctttcacatg gtctacaatt
    13921 aagtcctgtt ggacaagtat taattgaaaa gagtataaaa ggttggaaag aaatagaata
    13981 tgaggtaata agagattcaa agggaaattg tatagttgta tgtaacatgg aaaatataga
    14041 cccagtcgga gttcatacag gagacagtat agttgttgct ccaactcaaa ctttaagtaa
    14101 caaagaatgt gcaatgctta aaaaagcatc tttagatata ttaaatgcag tagaagttca
    14161 aggtggttgt aacgttcaat ttgcacttaa tccacatagt tttgaatatg cagttataga
    14221 gataaatcca agagttagta gatcatcagc tttagcatca aaagctacag gatatccaat
    14281 agctaaagtt tcatcaaaaa tagctttagg ttatacttta gatgagatag aaaatgcagt
    14341 aactaaaaaa acttatgctt gttttgaacc aactatagat tatgtggtgg caaaaatacc
    14401 aaaatggcct tttgataaat ttaaaaaagc aaatagaaaa ttaggaacta agatgatggc
    14461 aactggtgaa attatgagta taggaagtaa ctttgaggct gctattctta aagggataag
    14521 atcacttgaa acaggaaaat attcattagt tcacacacca tctgaggaga gaagcattga
    14581 ggaattaaag aaaagagtag tagtacctga tgatgagaga ctatttgact tagctgaaat
    14641 gataagaaga ggctataaag tagaaatgat agaacaaatt acaggtatag ataaatggtt
    14701 tataaataaa tttaaatgga tagtagagca agaagaaaaa ttaaaagtta tgaaaattga
    14761 agatttaact aaagactatc ttcttgaatt aaagaaaaag ggattctctg ataaaggtat
    14821 atctgaccta atgaagataa gtccagaaaa attatatgaa ttgagaagtc tatacaatat
    14881 caaaccagca tataaaatgg ttgatacttg tgcaggtgag atagatgcta tatctcctta
    14941 ctattattca acttatgagc aatatgatga ggtagttgtt agtgataaga aaaaggtgat
    15001 agtattaggt tctggtccaa taagaatagg tcaaggtata gaatttgact attgttcagt
    15061 tcattgtgta aaatctttaa gaaaaatgga catagaaact ataatcataa acaataaccc
    15121 tgaaactgta agtacagact ttgatacatc agataagctg tattttgaac cattaacaga
    15181 agaagaagtt ttaagtataa tagaaaaaga aaagccagaa ggtgtaatac tacagtttgg
    15241 tgggcaaaca gctataaaat tggctaagtt tttacatgaa aaaaatatac ctatattggg
    15301 aactgatttt gatgatatag atgcagcaga agatagagaa aaatttgatg atttactaga
    15361 gagactagat ataaatagac caaaaggaaa gggtgtatgg tcacttaacg aaggcattga
    15421 agttgctaat gagttaggtt atccagtatt agttagacca tcttatgtac ttggtggtca
    15481 aggtatggaa ataacttata acgaagaaaa attatctcaa tacctacaag atgcatttga
    15541 tagagaccat aaaaatccag tacttataga taaatatcta actggtagag aaatagaagt
    15601 agatgctata tgtgataagg aagatatatt gatacctggt ataatggaac atttagaaag
    15661 agctggagtt cactctggag atagtacaac aatgtatcca agtcaaaata tatctgatga
    15721 aataaaagaa aagatagtag aatacactaa aaaaatagct ttagacctta atgtgcttgg
    15781 tatggttaat atacagttta tagaatttca aaatgaatta tatataattg aggttaaccc
    15841 tagagctagt agaacagttc cgtatataag taaagtaagt ggagtaccaa tagttgactt
    15901 ggctactaag tgtatgttag gagctaaatt aaaggattta ggatatggta caggagttta
    15961 caaagagcca aaattagtat cagtaaaagt accagtattc tcaatgtcta aattatctaa
    16021 agttgaagta agtctaggac ctgaaatgaa gtctacagga gaagttctag gtgtaggaga
    16081 aaatttagaa g
//
LOCUS       DACTZW010000093        15972 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.093, whole genome shotgun sequence.
ACCESSION   DACTZW010000093 DACTZW010000000
VERSION     DACTZW010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15972)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15972)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15972
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.093"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            248..397
                     /gene="rpmG"
                     /locus_tag="JAM15_15830"
     CDS             248..397
                     /gene="rpmG"
                     /locus_tag="JAM15_15830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAT6799719.1"
                     /translation="MRVKVTLACTECKQRNYNTTKNKKNNPDRIELQKYCRFCKKHTT
                     HKETK"
     gene            423..644
                     /gene="secE"
                     /locus_tag="JAM15_15835"
     CDS             423..644
                     /gene="secE"
                     /locus_tag="JAM15_15835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HAT6799720.1"
                     /translation="MAAQKNDGAKTKKRFSLFGYLKETKQELKRVTWPTKKELFKNTS
                     IVLTVVISCTILVWGIDTILSGALALLLK"
     gene            664..1206
                     /gene="nusG"
                     /locus_tag="JAM15_15840"
     CDS             664..1206
                     /gene="nusG"
                     /locus_tag="JAM15_15840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination factor
                     NusG"
                     /protein_id="HAT6799721.1"
                     /translation="MSELQEASWYVVHTYSGHENKVKATIEKAVKTRGMEDCIRQVVV
                     PTEEVVETTKTGKEKTRQRKVYPSYVLVKMIITDESWYVVRNTKGVTGFVGPGSKPVP
                     LSEDEVKAMGIDTTDPKVVNSDIDFEIGDTVKVSQGPFSGQIGNIEEIDLENREVKVC
                     INAFGKRTLFVIELEGIEKI"
     gene            1242..1667
                     /gene="rplK"
                     /locus_tag="JAM15_15845"
     CDS             1242..1667
                     /gene="rplK"
                     /locus_tag="JAM15_15845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HAT6799722.1"
                     /translation="MAKKVIGQIKLQIPAGKATPAPPVGPALGQHGVNIMGFTKEFNA
                     KTADQAGMIIPVVITVYQDRSFSFITKTPPAAVLIKKALNLKSGSGEPNKKKVAKMTS
                     AQVREIAELKMPDLNAASVEAAMSMIAGTARSMGVVIED"
     gene            1737..2435
                     /gene="rplA"
                     /locus_tag="JAM15_15850"
     CDS             1737..2435
                     /gene="rplA"
                     /locus_tag="JAM15_15850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002846502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HAT6799723.1"
                     /translation="MAKKGKRYAGALQKVDRTKFYDASEALTLVSDIAGAKFDETVEA
                     HIKLGVDSRHADQQVRGAVVLPHGTGKTKRVLVFAKGEKAKEAEQAGADFVGAEELVQ
                     KIQGENWFDFDIVVATPDMMGVVGRLGRVLGPKGLMPNPKSGTVTFDVAKAIDEIKAG
                     KVEYRLDKTNIIHVPVGKVSFGGEKLTENFTALMDAIIKAKPAAAKGQYLRSITVASS
                     MGPGVKINPARTAE"
     misc_feature    2487..2615
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            2658..3164
                     /locus_tag="JAM15_15855"
     CDS             2658..3164
                     /locus_tag="JAM15_15855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HAT6799724.1"
                     /translation="MRKAIEIKSEVVSEIVEKLQKSSAAVVVDYKGLTVEEVTELRKQ
                     MREAGVDYKVYKNTLVRRAAKEVGIEQFNDELLVGTNAIAFGYDDPVAPARILKGFMD
                     SHPKMKLKMGIVEGAFYDESKIVEMANIPSREVLIAKLLGSLKAPVSNFAYLIDAIAK
                     KAEGQEEA"
     gene            3222..3587
                     /gene="rplL"
                     /locus_tag="JAM15_15860"
     CDS             3222..3587
                     /gene="rplL"
                     /locus_tag="JAM15_15860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002842856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HAT6799725.1"
                     /translation="MTIEQILEAIENMKVLELNELVKAAEEKFGVSASAPVMVAGAAV
                     GGPAAEEKTEFDVVLTDVGSSKVGVIKAVREITGLGLKEAKEVVDNAPKTVKEGASKE
                     EADQIKEKLEAAGAKVEVK"
     gene            3979..4767
                     /locus_tag="JAM15_15865"
     CDS             3979..4767
                     /locus_tag="JAM15_15865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAT6799726.1"
                     /translation="MEKLQGKIAVVTAATKGIGLASAEILAKNGATVYLAARSEELAN
                     EVINKISAEGGCAKFVYFNAREEETFTSMIEEVVKKEGKIDILVNNFGSTNPSLDKDL
                     VTGDTDNFFDTVNTNLKSVYLPCKAAIPHMIKNGKGSIVNISSIGSVLPDLSRIAYCV
                     SKAAINSLTQNIATQYAKDNVRCNAVLPGLIATKAALDNMSPEFIKEFLKHVPLNRIG
                     EPDDIAKAVLFYASDDSSFITGDLLEVAGGFGLPTPQFADNILG"
     gene            5238..8954
                     /locus_tag="JAM15_15870"
     CDS             5238..8954
                     /locus_tag="JAM15_15870"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HAT6799727.1"
                     /translation="MPHPVTIGKRTRMSFSKIKEIADVPNLIEIQVDSYEWFLKEGLK
                     EVFDDISPIEDYTGNLILEFVDYSLDDKPKYDIEECKERDATYCAPLKVKVRLINKET
                     GEIKEQEVFMGDFPLMTERGTFVINGAERVIVSQLVRSPGVYYAEERDKTGKRLISST
                     VIPNRGAWLEYETDSNDVISVRVDRTRKQPVTVLLRALGIGTDAEIIDLLGEDERLSA
                     TLEKDNTKTVEEGLVEIYKKLRPGEPPTVESASSLLNALFFDPKRYDLAKVGRYKFNK
                     KLALCYRIMNKISAEDIINPETGEVFVKAGEKISYDLAKAIQNAGINVVNLLMDDDKK
                     VRVIGNNFVDIKSHIDFDIDDLNIKEKVHYPTLKEILDGYSDEEEIKEAIKSRIKELI
                     PKHILLDDIIASISYEFNIFYNIGNIDDIDHLGNRRIRSVGELLQNQVRIGLSRMERV
                     IKERMTVQDMEAITPQALVNIRPVSAAIKEFFGSSQLSQFMDQTNPLSELTHKRRLSA
                     LGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLGTYAKINEFGFIESP
                     YRKFDKETSTVTDEIHYLTADEEDLFVRAQANEPLTEDGKFVNHRVVCRTVNGAVEMV
                     PESRVDYMDISPKQVVSVATAMIPFLENDDANRALMGANMQRQAVPLVRREAPIIGTG
                     IEYRAAKDSGAVVVARNSGIAERVTADEIIIKREDGNRDRYNLLKFKRSNSGTCINQT
                     PIINKGDQIIKGDVIADGPATDLGEVALGRNCLIAFMTWEGYNYEDAILINERLVKED
                     RLSTIHIEEYECEARDTKLGPEEITRDIPNVGDSAIKNLDDRGIIRIGAEVDSGDILV
                     GKVTPKGETELTAEERLLRAIFGEKAREVRDTSLKVPHGESGIIVDVKVFTRENGDDL
                     SPGVNELVRCYIAKKRKIKVGDKMAGRHGNKGVISRVLPEEDMPFMENGTPLDIILNP
                     QGIPSRMNIGQVLEVHLGLAAKTLGWYVATSVFDGANEYDIMDALEEAGYPRDGKLTL
                     YDGRTGQSFDNRITVGYMYYLKLHHLVDEKLHARSTGPYSLVTQQPLGGKAQFGGQRF
                     GEMEVWALEAYGAAHILQEILTVKSDDVVGRVRTYEAIVKGENIPEPGIPESFKVLIK
                     ELQSLCLDVKVLTEEDQEIEVRESVDEDDTIGEFELDVVNHMGEVEESNIIEEIEDDF
                     AENAEDEDIENLEEFTEDDLFEEEIDFDSDDFDM"
     gene            8996..12481
                     /gene="rpoC"
                     /locus_tag="JAM15_15875"
     CDS             8996..12481
                     /gene="rpoC"
                     /locus_tag="JAM15_15875"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HAT6799728.1"
                     /translation="MFELNNFESIKIALASPEKIRQWSRGEVKKPETINYRTLKPEKD
                     GLFCERIFGPQKDWECHCGKYRRVRYKGVVCDRCGVEVTKSKVRRERMGHIELAAPMS
                     HIWYFKGIPSRMGLLLDMSPRSLEKILYFASYVVVDPGETGLNEKQLLTEKEYRTALE
                     KYGYTFTVGMGAEAVKTLLQNIDLEQQSKDLRAELKDSTGQKKVRTIRRLEVVEAFKK
                     SGNKPEWMILDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLELGA
                     PDIIVRNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPELKFYQCGLPKKMALELFKPFVMDKLVKEGYAHNIKSAKSIVEK
                     VKPEVWDVLEDVIKSHPVLLNRAPTLHRLGIQAFEPILVEGKAIKLHPLVCTAYNADF
                     DGDQMAVHVPLSVEAQAEARFLMLSVNNILAPKDGSPITTPSQDMVLGCYYLTIEAQD
                     GAKGTGMVFKDFNELLLAYYNKSVHLHALVKLKVTLEDGRSSLVESTVGRFIFNENIP
                     QDLGFVDRKENPFALEVDFLADKKSLGKIIDKCFRKHGNTETAELLDYIKALGFKYST
                     LGGITVAVDDMSVPEEKKVFIAEAEAKVDKYEKAYRRGLISDEERYEKVIETWTETTD
                     KVTDALMGGLDRLNNIYIMAHSGARGSKNQIRQLAGMRGLMANASGKTVEIPVKSNFR
                     EGLSVLEYFTSSHGARKGLADTAIRTAESGYLTRRLVDVSQDVIVREIDCGTEDTTEI
                     YAIKEGNEVIEEIYDRIVGRYTIDPILNPETGEVLVEADSMIQEDEAETIVALGIEKI
                     RIRTVLNCKTNHGVCSKCYGRNLATGKEVNIGEAVGIIAAQSIGEPGTQLTMRTFHTG
                     GVAGADITQGLPRVEELFEARKPKGLAVITEVSGRVEIDETGKRKEVNVIPEEGETQT
                     YVIPYGSRLKVKQGQMLEAGDPLTQGFINPHDIVRVNGVKGVQEYIVKEVQRVYRLQG
                     VDVNDKHIEVIVRQMLSKVKVEDPGDTDLLPGGYEDVLTFNECNKDAIDKGLRPAVAK
                     RVLLGITKASLATDSFLSAASFQETTRVLTEAAIKGKEDHLIGLKENVILGKLIPAGT
                     GMKKYRNIAVEKIED"
     gene            12770..13192
                     /gene="rpsL"
                     /locus_tag="JAM15_15880"
     CDS             12770..13192
                     /gene="rpsL"
                     /locus_tag="JAM15_15880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HAT6799729.1"
                     /translation="MPTINQLVRKSRKALEKKSTAPALQKGYNSLNKKVTDASAPQKR
                     GVCTSVKTVTPKKPNSALRKVARVRLTNGIEVSAYIPGEGHNLQEHSVVLIRGGRVKD
                     LPGVRYHILRGTLDTAGVDKRRQSRSKYGAKRPKEAKK"
     gene            13315..13785
                     /gene="rpsG"
                     /locus_tag="JAM15_15885"
     CDS             13315..13785
                     /gene="rpsG"
                     /locus_tag="JAM15_15885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007788527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HAT6799730.1"
                     /translation="MPRKGNIPKREVLPDPMYGSKVVTKLINNLMVDGKKGKSQRIVY
                     DAFAIVAEKTGEEALEVFNKAMDNIMPVLEVKARRVGGANYQVPIEVRPERRQTLGLR
                     WLVKYTRARGEKGMVEKLAKEIMDAANNTGASVKKKEDTHKMAEANKAFAHYRW"
     gene            13834..15900
                     /gene="fusA"
                     /locus_tag="JAM15_15890"
     CDS             13834..15900
                     /gene="fusA"
                     /locus_tag="JAM15_15890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009527607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HAT6799731.1"
                     /translation="MARKFPLEKTRNIGIMAHIDAGKTTTTERILFYTGQTHKIGETH
                     EGASQMDWMEQEKERGITITSAATTASWKDHRINIIDTPGHVDFTVEVERSLRVLDGS
                     VAVFCAKGGVEPQSENVWRQAETYGVPRIAFINKMDILGADFYNVISMMKSRLNSNAV
                     PMQLPIGKEDSFIGIIDLLKMDAVIYKDDLGVEMEETDIPEDMKELAAEWREKLVESV
                     AETDEELMMKYLEGEELTIDELKVAIRKATIACEMNPVFCGTAYRNKGVQLVIDAVLD
                     YLPAPTDIPAIKGILADGEEAERHSSDEEPFSALAFKIMTDPFVGKLAFFRVYSGTLE
                     SGSYVLNATKNKRERIGRILQMHANTREEITKVYAGDIAAAVGLKDTTTGDTLCDPAN
                     PIILESMEFPEPVISVAIEPSSKAAQEKMGIALQKLAEEDPTFTVKTDQETGQTIISG
                     MGELHLEIIVDRLLREFKVEAKVGAPQVAYRETITQPVDVEYKYSKQSGGRGQYGHVK
                     IRVAPQEPGEGYKFTNKTVGGSVPKEYVGPVDMGIQGAMQSGIVAGYPVVDVAVELYD
                     GSYHEVDSSEMAFKMAGSMAFKDAMKKGNAVLLEPYFKVEVVTPEDYMGDVMGDLNSR
                     RGLIQGMEARSGAQVINAFVPLSEMFGYSTDLRSSTQGRATYTMIFDHYEQVPASVAK
                     KIAEGK"
BASE COUNT         6252 a         1987 c         3252 g         4481 t
ORIGIN      
        1 ctttactaaa ctgatggatt aaaaggaata acaaaaagag gggttaggct cctctttttt
       61 taacatagaa atacaaaaac attgacacag cataggattt tgtgataact tatacaaggt
      121 aatgattata ggaagttaat aatatcttga atactgtaga tttttaataa atacatattt
      181 taaagatatt atattcacat atattaacaa tatatattat tgtattacaa agttggaggt
      241 gtatcagatg agagttaaag taactttagc atgtacagag tgtaagcaaa gaaactacaa
      301 cactactaag aataagaaaa ataatccaga cagaatagaa ttacaaaaat attgtagatt
      361 ctgtaaaaag catacaactc ataaagaaac aaaatagttt tttataagga tgtgagtatg
      421 gaatggctgc ccaaaaaaat gacggtgcaa aaactaaaaa aaggtttagt ttatttggat
      481 atttaaaaga aactaagcaa gaattaaaaa gagttacatg gccgacaaaa aaggaactgt
      541 ttaaaaacac aagtatagtt ttaactgtag ttatttcatg cactatatta gtatggggta
      601 tagacactat attatctggt gcactagcgt tattactaaa atagacgaaa agaggtaagt
      661 taaatgtcag aattacaaga agcaagttgg tatgtagttc atacctattc gggacatgaa
      721 aataaagtta aagctacaat tgagaaagca gttaaaacaa gaggtatgga agactgcata
      781 agacaagtag ttgttccaac agaagaggta gtggaaacta ctaaaactgg aaaagaaaaa
      841 actagacaac gtaaagttta tccaagttat gtcttggtta aaatgataat aactgatgaa
      901 tcttggtatg tagtaagaaa tactaaggga gttacaggtt tcgttggacc tggttcaaaa
      961 ccagtaccat taagtgaaga tgaagtcaaa gctatgggga tagatacaac agaccctaaa
     1021 gtagtaaata gcgatattga ttttgaaata ggagacacag taaaagtatc tcaaggacca
     1081 tttagtggac aaataggtaa catagaagaa attgacttag aaaatagaga agtcaaagta
     1141 tgcataaatg catttggtaa aaggactcta tttgtaatag agcttgaagg tatagaaaaa
     1201 atctaatact atatagaaaa atctgaggag gtgcgctcaa aatggctaaa aaagttatag
     1261 gtcaaataaa attacaaata cctgcaggaa aggctactcc agcgccacca gttggaccag
     1321 cattaggaca acatggtgtt aatataatgg gattcacaaa agaatttaat gctaaaactg
     1381 cagatcaagc tggaatgata ataccagttg ttataactgt atatcaagat agatcattca
     1441 gttttataac aaaaactcca ccagctgcag ttttaattaa aaaagcatta aacttaaaat
     1501 caggttctgg agaaccaaac aaaaagaaag ttgctaaaat gacttcagct caagtaagag
     1561 aaatagctga gttaaaaatg cctgacttaa atgctgcatc agtagaagct gctatgagta
     1621 tgatagctgg tactgctaga agcatgggtg ttgtaatcga agactaatta aaagatacac
     1681 tttttttata aagtgggagg cgagaagccg aaattaacca caaggaggaa aataaaatgg
     1741 ctaaaaaagg taaaagatat gcaggtgcat tacaaaaagt agatagaact aaattttatg
     1801 atgcatcaga agcattaaca ttagtttcag atatagctgg agctaaattt gatgagacag
     1861 tagaagcaca cattaaatta ggtgttgact caagacatgc tgaccaacaa gtaagaggtg
     1921 cagttgtatt acctcatgga actggtaaaa caaaaagagt tttagttttt gctaaaggtg
     1981 aaaaagctaa agaagctgaa caagctggtg ctgactttgt aggagctgaa gaattagttc
     2041 aaaaaataca aggtgaaaac tggtttgact ttgatatagt agttgctact ccagatatga
     2101 tgggtgtagt aggtagatta ggtagagtat taggacctaa aggtttaatg ccaaacccta
     2161 aatcaggaac agttacattt gatgtagcta aagctataga tgaaataaaa gctggtaaag
     2221 ttgaatacag attagacaaa actaacataa tacacgttcc agtaggaaaa gtatcatttg
     2281 gtggagaaaa attaactgaa aactttactg cattaatgga tgctataata aaagctaaac
     2341 cagctgctgc taaaggacaa tatttaagaa gtataacagt agcttcttca atgggacctg
     2401 gagttaaaat aaacccagca agaacagctg aataataaaa ctgttgacac aggttgacaa
     2461 aaatgttatt atatcacttg tcaatgtaaa aaagaataga tttgccgtag atagtgggtg
     2521 cgaaagctta atatcccgcc gaggttttag ataaattgag attactaaag cttttgatgt
     2581 ctacttttgg caacaaaagc tttttataat gttgcggtaa atactaagcc tatttggtga
     2641 aggaggtgca catctatatg agaaaagcta tagaaattaa atcagaagtt gtttctgaga
     2701 tagttgaaaa gttacaaaaa tcttctgctg ctgttgttgt agattacaaa ggattaacag
     2761 ttgaagaagt aactgagtta agaaaacaaa tgagagaagc tggtgtagat tacaaagtat
     2821 acaaaaatac tttagttaga agagcagcta aagaagttgg tatagagcaa tttaatgatg
     2881 aattattagt tggaactaat gccatagcat ttggatatga tgatccagtt gctccagcta
     2941 gaatattaaa aggattcatg gattctcatc caaaaatgaa attaaagatg ggtattgtgg
     3001 aaggtgcatt ctatgatgaa tctaagattg ttgaaatggc taacatacca tcaagagaag
     3061 ttcttatcgc taaattactt ggtagcttaa aagctccagt atcaaacttc gcatacttaa
     3121 tagatgcaat agcgaaaaag gcagaaggtc aagaagaagc ttaattgctt aactaaaaaa
     3181 ttataaatat taatttgaaa taaaattcgg aggtgctaaa aatgacaata gaacaaatat
     3241 tagaagctat agaaaatatg aaagttttag aattaaatga attagttaaa gctgctgaag
     3301 aaaaattcgg tgtatcagct tcagctccag taatggtagc tggtgcagct gttggtggac
     3361 cagctgctga agaaaaaact gagtttgatg tagtattaac tgacgttggt tcttcaaaag
     3421 ttggagttat aaaagcagtt agagaaataa caggattagg attaaaagaa gctaaagaag
     3481 tagttgacaa tgctcctaag acagttaaag aaggagcttc taaagaagaa gctgatcaaa
     3541 taaaagagaa attagaagct gctggagcta aagtagaagt taagtagttt ctttaaaaag
     3601 atacccattg ggtatctttt tttatttata aaaaactata aagaaagtat ttggaattat
     3661 aaagaaagtg tttttataaa ataaaaaaaa attatataat agtactaaat taagggtatc
     3721 atatatggtg taatggtgtt ttaatttaac attattatca aattaaaata taaacaattg
     3781 ttgtaatgtc tgtatataaa gtatataatt aaactaaaat gtaaaatttt acattttagt
     3841 ttaaaaaaat acacgagtgt tttataaata aaatgtaata aataattaat taacaaatat
     3901 aaattttaaa ataagttaga tatttagaaa aatcgaaatt tgtaggattt aaaggacata
     3961 ttcaaggagg agttaataat ggaaaaatta caaggaaaaa ttgcagtagt tactgcagca
     4021 acaaaaggta ttggattagc atcagcagag atattagcaa aaaatggagc aactgtgtac
     4081 ttagcagctc gttcagaaga attagctaat gaagttataa ataaaataag tgcagaaggt
     4141 ggttgtgcta agtttgttta ctttaatgct cgtgaagaag agacctttac ctcaatgata
     4201 gaagaggtag ttaaaaaaga aggtaagata gatatacttg taaacaattt tggttcaaca
     4261 aacccttctc ttgacaaaga ccttgtaact ggggatacag ataatttctt tgacacagta
     4321 aatactaatt taaaaagtgt gtatttacca tgtaaagcag caattcctca tatgataaag
     4381 aatggaaaag gaagtatagt aaatatatca agtataggtt cagtattacc tgatttatct
     4441 agaatagctt actgtgtatc aaaagcagca atcaactcat taactcaaaa catagctaca
     4501 caatatgcta aagacaatgt tagatgtaat gctgtacttc cagggcttat tgcaactaaa
     4561 gcagcattag acaatatgtc tccagagttc ataaaagaat ttttaaagca tgttccttta
     4621 aatcgtatag gggaaccaga tgatatagca aaagctgttc tattctatgc tagtgatgac
     4681 tcatcattta taacagggga tttacttgaa gttgcaggag gatttggttt acctactcca
     4741 caatttgcag ataatatatt aggataatta aattactaat atgcaatgaa agcttatgca
     4801 ttagttatag tagaaatgat atttttataa aggccataga tataatttat attggaaagg
     4861 tttgaggttc aaaattccaa gttaaattta tttatggtct ttattttgta tattttaata
     4921 aattgtatat atttgtataa atgtaattat ttacaatcat tttaatatgg aattataatt
     4981 aaataggggg gatggtactt gtataaaatt ttttatagaa aattagacct ataaatgaaa
     5041 aatatggatt ttatattgga aaattgtaca taatacataa tatatgctta aaataattta
     5101 caaaaaatca aaaataatgc atagtttaca tataagataa aaaatatatt gaaaaatact
     5161 tgacattatg ctaaaattat tagatgcgtt agaatgaact attgttttat ttttaattat
     5221 tgagaggtga aaagtgaatg ccacatcctg tcacgatagg taaaagaact agaatgagct
     5281 tttctaaaat taaggaaata gctgatgtgc caaatcttat agaaattcaa gtagattcct
     5341 atgagtggtt tttaaaagaa ggtttaaaag aagtgtttga tgatatttca ccaatagaag
     5401 attatactgg taatcttata ttggaatttg tcgactattc tctagatgat aaaccaaagt
     5461 acgatataga agagtgtaaa gagagagatg ctacatattg tgcacctcta aaggttaagg
     5521 taagacttat aaataaagaa acaggtgaga taaaagaaca agaagtgttt atgggtgact
     5581 tccctttaat gacagaaaga ggaactttcg ttataaatgg agcagaaaga gttatagtaa
     5641 gtcaattagt tagatctcct ggtgtttact atgcggaaga aagagataaa acaggtaaga
     5701 gattgatttc atctactgta attcctaata gaggagcatg gttagaatat gaaacagatt
     5761 ctaatgatgt aatatctgta agagttgata gaacaagaaa acaaccagtt acagttttac
     5821 ttagagcttt aggaatagga acagatgcag agataattga ccttttagga gaagatgaga
     5881 gattatctgc tacattagaa aaagataata ctaagacagt agaagaaggt cttgtagaga
     5941 tatacaaaaa attaagacca ggtgaacctc ctactgtaga aagtgcatca tctttattaa
     6001 atgctttatt ctttgaccca aaaagatatg acctagcaaa agttggtaga tataaattca
     6061 ataagaaact tgctttatgt tatagaataa tgaataaaat ttcagcagaa gacataataa
     6121 atccagaaac tggagaagta tttgtaaaag ctggagaaaa aataagctat gatttggcta
     6181 aagccataca aaatgcaggt ataaatgtag taaatctact aatggatgat gataaaaaag
     6241 ttagagttat aggaaataat tttgtggata ttaagtctca cattgatttt gacatagatg
     6301 atttaaacat aaaagaaaaa gtacattatc caactttaaa agaaatttta gatggatata
     6361 gtgatgaaga agaaataaaa gaggctataa aatcaagaat taaagaactt ataccaaaac
     6421 atatattatt agatgatata atagcttcaa taagttatga gttcaatata ttctataata
     6481 taggaaatat tgatgatata gatcacctag gaaacagaag aataagatct gtaggtgaat
     6541 tgttacaaaa tcaagttaga attggtcttt caagaatgga aagagttata aaagaaagaa
     6601 tgacggttca agatatggaa gctataacgc ctcaagcgtt agttaacata agaccagttt
     6661 cagctgcaat aaaagaattt tttggtagtt ctcagttatc tcagttcatg gatcaaacaa
     6721 atcctctatc tgagttaacg cataagagaa gattatcagc ccttgggcct ggaggtcttt
     6781 caagagaaag agctggattc gaagtgcgtg acgttcacca ttcacactat ggtagaatgt
     6841 gtccaataga gactccagag ggaccaaata tcggtcttat aaactctcta ggaacttatg
     6901 caaaaataaa tgaatttgga tttatagaat caccatatag aaaatttgat aaagaaacat
     6961 caacagttac tgatgaaata cattatttaa ctgctgacga agaagattta ttcgtaagag
     7021 ctcaggcaaa tgagccatta acagaagatg gtaaattcgt aaaccataga gttgtttgta
     7081 gaactgtaaa tggtgctgtt gaaatggttc ctgaaagtag agtagattac atggatatat
     7141 ctcctaagca ggttgtatct gttgccactg ctatgatacc tttcttagaa aatgatgatg
     7201 ccaaccgtgc ccttatggga gcgaacatgc agcgtcaggc agtgcctcta gttagaagag
     7261 aagcaccaat tataggaact ggtatagaat acagagcagc aaaagactct ggagcagttg
     7321 ttgttgctag aaattctggt atagcagaaa gagtaacagc agatgaaata attataaaaa
     7381 gagaagatgg aaacagagat agatataatc tacttaagtt taaacgttca aactcaggta
     7441 cttgtataaa tcaaacacct ataataaata agggtgacca gataataaaa ggtgatgtta
     7501 tagcagatgg tccagcaact gatttaggag aagttgcact tggaagaaac tgtcttatag
     7561 cattcatgac ttgggaaggt tataactacg aggatgctat attaataaat gaaagattag
     7621 ttaaagaaga tagattatca acaattcata tagaagaata tgaatgtgaa gctagagata
     7681 caaaactagg gccagaggaa ataactagag atatacctaa tgttggagat agtgcaatca
     7741 aaaacttaga tgatagaggt ataataagaa taggtgcaga agtagactca ggtgatatat
     7801 tagttggtaa ggtaactcca aaaggagaaa ctgaacttac tgctgaggaa agattacttc
     7861 gtgcgatatt cggagaaaaa gccagggaag ttagagatac ttcacttaaa gtacctcatg
     7921 gtgaatctgg tataatagtt gatgtaaaag tatttactag agaaaatgga gatgatttat
     7981 ctccaggagt aaatgaatta gtaagatgtt atatagctaa aaagagaaag ataaaagttg
     8041 gagataagat ggctggtcgt catggtaata aaggggttat ctcgagagta ttacctgaag
     8101 aagatatgcc attcatggaa aatggaacgc cattagatat aatacttaac ccacaaggta
     8161 taccatcacg tatgaacatc ggtcaggttc tagaagttca tttaggactt gctgctaaga
     8221 cattaggatg gtatgtagca acatcagtat tcgatggtgc taatgagtat gacataatgg
     8281 atgctcttga agaagctgga tatcctagag atggtaaatt aactttatat gatggtagaa
     8341 caggtcaatc ttttgacaat agaataactg ttggatatat gtattacttg aaactacatc
     8401 acttagtaga tgaaaaacta catgcaagaa gtactggacc atactcatta gttactcaac
     8461 agccactagg tggtaaagca caatttggtg gacaaagatt tggagagatg gaggtttggg
     8521 ctctggaagc atatggagct gctcacatac ttcaagaaat acttactgtt aagtctgatg
     8581 acgttgtagg tcgtgttaga acatatgaag ctatagttaa aggtgaaaat atacctgaac
     8641 caggaatccc agaatcattt aaggttctta taaaagaact tcaaagttta tgcttagatg
     8701 taaaagtatt gacagaggaa gaccaagaaa tagaagtaag agaatctgtg gatgaagatg
     8761 atacaatagg tgaatttgag ctagatgttg taaatcatat gggagaagtt gaagaaagta
     8821 atataataga agaaattgaa gatgattttg cagaaaatgc agaagatgag gatatagaga
     8881 atttagaaga attcactgaa gatgatttat ttgaagaaga aatagatttt gatagtgatg
     8941 actttgatat gtaaatttaa ttaatgtaaa tctcaaatag aagggagaga actccttgtt
     9001 tgaattaaac aatttcgagt cgataaaaat agcattggct tctccagaaa aaataagaca
     9061 atggtctagg ggagaagtta aaaagccaga aactataaat taccgtactt taaaaccaga
     9121 aaaagatggt cttttctgtg aaagaatatt tggaccacaa aaagactggg agtgccactg
     9181 tggtaaatat agaagagtta gatataaagg tgtagtttgt gatagatgtg gagtagaagt
     9241 aactaaatca aaagtaagaa gagagagaat gggacatata gagctagctg ctcctatgtc
     9301 tcacatctgg tacttcaaag gtataccaag tagaatggga cttttacttg atatgtcacc
     9361 aagatcgtta gaaaaaatat tatactttgc ctcatatgtg gtagttgatc caggagagac
     9421 tggattaaac gaaaaacaat tgcttacaga aaaagaatac agaactgctc ttgaaaagta
     9481 tggatatact tttactgtag gaatgggtgc tgaagctgta aagacattac tacaaaatat
     9541 agatttagag caacaaagta aagacctaag agcggagtta aaagatagta cagggcaaaa
     9601 gaaagttaga acaataagaa gattagaagt tgtagaggca tttaaaaagt ctggaaataa
     9661 accagaatgg atgattttag atgcaatacc agtaatacca ccagatttaa gaccaatggt
     9721 acaacttgat ggtggaagat ttgcgacttc agacctaaat gatttatata gaagagttat
     9781 aaatagaaac aatagactta aaagattatt agagcttgga gctccagata taattgtaag
     9841 aaatgaaaaa agaatgcttc aagaagctgt tgatgcattg atagataatg gtagaagagg
     9901 tagacctgta acaggacctg gaaatagacc acttaaatct ttatcagata tgttaaaagg
     9961 taagcaaggt cgtttccgtc aaaacttact tggtaagcgt gttgactact caggacgttc
    10021 tgttatagtt gttggaccag aacttaaatt ttatcaatgt ggacttccaa agaagatggc
    10081 attagaatta ttcaagccat ttgttatgga taaattagtt aaagagggtt atgcacataa
    10141 tataaaaagt gcgaaatcta tagtagaaaa agttaagcca gaagtttggg atgttttaga
    10201 agatgttata aaaagtcatc cagttcttct taaccgtgca ccgactctac atagattagg
    10261 tatacaagca tttgaaccaa tcttagttga gggtaaggct ataaaactac atcctcttgt
    10321 atgtacagct tataatgcag actttgatgg tgaccaaatg gcagtccatg tacctttatc
    10381 agtagaagca caagcagaag caagattctt aatgctttct gtaaataata tacttgctcc
    10441 taaagatggt tcacctataa ctactccatc tcaggatatg gttttaggtt gctattatct
    10501 aacaatagaa gcccaagatg gagctaaagg aacaggtatg gtatttaaag actttaatga
    10561 actattactt gcttattaca ataaatcagt tcatctacat gcattagtga aactgaaggt
    10621 aacacttgaa gatggaagaa gttcattggt tgaaagtact gttggtagat ttatatttaa
    10681 tgaaaatata cctcaagact taggttttgt agatagaaaa gaaaatccat ttgcacttga
    10741 agttgatttc ttagcagata aaaaatctct tggtaaaata atagataaat gctttagaaa
    10801 acacggaaat acagaaacag ctgaattact agattatata aaagctctag gatttaaata
    10861 ttctacatta ggtggtataa cagttgctgt tgatgatatg agtgtcccag aagaaaagaa
    10921 agtatttata gctgaggcag aagctaaagt tgataagtat gaaaaagcat acagaagagg
    10981 tctaatctct gatgaagaaa gatatgaaaa agttatagag acatggacag aaacaactga
    11041 taaagttact gatgctctta tgggtggact agatagatta aataatatat atataatggc
    11101 acattcagga gccagaggtt ctaaaaacca aattagacag ctggcaggta tgcgtggtct
    11161 tatggcaaat gcatctggta aaacagttga gataccagtt aaatctaatt tccgtgaagg
    11221 tttatcagta ctagaatact ttacatcttc acatggtgcc agaaaaggtc ttgccgatac
    11281 agctatacgt acagctgaat ctggatattt aacaagaaga cttgttgatg taagtcaaga
    11341 tgttattgta agggaaatag attgtggaac agaagatact acagagattt atgctataaa
    11401 agaaggaaat gaagttatag aagagatata tgatagaatt gtaggaagat atactataga
    11461 ccctatatta aatcctgaaa ctggagaagt tctagttgag gctgattcaa tgatacaaga
    11521 agatgaagca gaaactatag tagctttagg aattgaaaaa attaggataa gaacagttct
    11581 taactgtaaa actaatcatg gagtttgttc taagtgttat ggtagaaact tggcaacagg
    11641 aaaagaagtt aatataggtg aagcagttgg tataatagca gctcaatcta tcggtgagcc
    11701 gggtactcag cttacaatgc gtacattcca tactggagga gttgcaggag ctgatataac
    11761 tcaaggtcta ccaagggttg aagaattatt tgaagctaga aaaccaaaag gattagctgt
    11821 aataactgaa gtatctggta gagttgaaat tgatgaaaca ggaaagagaa aagaagtaaa
    11881 tgtaatacca gaagaaggcg agactcaaac atatgtaatt ccatatggtt ctagattaaa
    11941 agttaagcaa ggtcaaatgc tagaggctgg agaccctcta acacaaggat ttataaatcc
    12001 tcatgatata gtaagagtaa atggtgttaa gggagttcaa gaatatatag ttaaagaagt
    12061 tcaaagagtg tatagacttc aaggggttga tgttaatgat aagcatatag aagttatagt
    12121 aagacaaatg ctatctaaag taaaagttga agacccagga gatacagatt tattgccagg
    12181 tggatatgaa gatgtattaa cattcaatga atgtaataaa gatgctatag ataaaggtct
    12241 aagaccagca gttgctaaaa gagttttact tggtataact aaagcatctc ttgcaactga
    12301 ttcattctta tcagcagctt ctttccaaga aacaacaaga gtattaacag aggcagcaat
    12361 aaaaggtaaa gaagaccact taataggact taaagaaaat gttatattag gtaagttaat
    12421 accagcagga acaggaatga agaaatatag aaatatagct gttgaaaaaa ttgaagatta
    12481 atagcatata gagtaaagaa atcttgacaa ccattatttg tggtgttaaa atagtaaagt
    12541 gtgttgttta aaagtacact aagggcttga acaagttctt agtgactttt agatggcaat
    12601 aaatgagaac taaaaagcat caagctagaa aagtgctaat atcacatatt tatgtgttat
    12661 agacattaaa ttgtaagtaa cgaatgttac aatcagtcag tatgaatatt catattgatg
    12721 tagttggcgg tcactgataa gatcgaaaat ttggaaggag gtgcagatga tgccaacaat
    12781 taaccaatta gttcgtaaaa gtagaaaagc gctagagaag aaatctactg ctccagcatt
    12841 acaaaaaggt tacaactctt taaataagaa agtaactgac gctagtgccc cacaaaaaag
    12901 aggggtttgt acttcagtaa aaacagttac tcctaagaag cctaactcag ctttaagaaa
    12961 agttgccaga gttagattaa ctaatggtat agaagtttct gcttatatac caggagaagg
    13021 acacaactta caagagcata gtgttgttct tataagagga ggaagagtaa aagaccttcc
    13081 aggggttaga taccatatac taagaggtac tctagataca gcaggtgttg ataagagaag
    13141 acaatcaaga tctaaatacg gtgcgaagag acctaaagaa gctaaaaaat aaaacaatta
    13201 atgattgatt atagttcggt gctttaaata tatatatatt tacggcatca cggcattaaa
    13261 tgatttatgt cgagtaccta tgatttaagt taaataatta aggagggaag cgaaatgcca
    13321 agaaaaggta atattccaaa aagagaagtt ttaccagatc ctatgtatgg gagtaaggta
    13381 gttactaaat taataaataa tctaatggta gacggaaaaa aaggaaagtc tcaaagaata
    13441 gtttatgatg ctttcgcaat tgttgctgaa aagacaggag aagaagcttt agaagtattt
    13501 aataaagcaa tggataatat aatgcctgtt ttagaagtaa aagcaagaag agttggtgga
    13561 gcaaactacc aagtgccaat cgaagttaga cctgaaagaa gacaaacatt aggtttaaga
    13621 tggctagtaa aatatactag agctcgtgga gaaaaaggaa tggttgaaaa gctagctaaa
    13681 gagataatgg acgcagctaa caacactgga gcttcagtta agaaaaaaga agatactcat
    13741 aaaatggcag aagctaataa agcatttgct cattacagat ggtaggatat atagatatct
    13801 tataaattca aggatatcat aaggaggata accatggcta gaaagtttcc tttggaaaaa
    13861 actaggaata taggaatcat ggctcatata gatgcaggaa agactactac tacagaaaga
    13921 atcctgtttt atactgggca aactcataaa ataggagaaa ctcatgaagg agcttctcaa
    13981 atggactgga tggagcaaga aaaggaaaga ggtataacaa taacttctgc cgctactact
    14041 gcttcatgga aagaccatag aataaacata atagatactc ctggacacgt ggacttcaca
    14101 gttgaggttg aaagatctct aagagttctt gatggttcag ttgctgtatt ctgtgcaaaa
    14161 ggtggggttg agcctcaatc tgaaaatgta tggagacaag ctgaaactta tggagtacct
    14221 agaatagctt ttataaacaa aatggatata ttaggtgcag atttctacaa tgttataagc
    14281 atgatgaaat ctagattaaa ttctaatgca gttcctatgc aattaccaat aggtaaagaa
    14341 gattcattta taggtataat agacttatta aaaatggatg ctgttatata caaagacgac
    14401 ctaggggttg aaatggaaga aacagatata ccagaagata tgaaagaatt agctgctgag
    14461 tggagagaaa aattagttga atcagtagct gaaactgatg aagaattaat gatgaaatac
    14521 cttgaaggtg aagaacttac tatagatgaa ttaaaagttg ctataagaaa agctactata
    14581 gcttgtgaaa tgaacccagt tttctgtggt acagcttata gaaacaaagg tgttcagtta
    14641 gtaatagatg cagttttaga ttacttacca gcaccaactg atataccagc tataaaaggt
    14701 atattagcag atggagaaga agctgaaaga cattcttctg atgaagagcc attctctgca
    14761 ttagcattca aaataatgac tgacccattc gttggaaaac tagcgttctt cagagtttat
    14821 tctggaacat tagaatcagg ttcttatgtt ttaaatgcaa ctaagaataa gagagaaaga
    14881 attggtcgta tattacaaat gcatgctaat acaagagaag aaataactaa agtgtatgct
    14941 ggagatatag cagcagcagt aggattaaaa gatactacta ctggagacac attatgtgac
    15001 cctgctaatc caataatact tgaatctatg gaattccctg agccagttat atctgttgct
    15061 atagaaccaa gttctaaagc agctcaagaa aaaatgggta tagctcttca aaaattagct
    15121 gaagaagacc caactttcac agttaagact gaccaagaaa caggacaaac tataatatct
    15181 ggtatgggtg aattacactt agagataata gtagatagat tattaagaga atttaaagta
    15241 gaagctaaag ttggtgcacc acaagttgca tatagagaga ctataactca accagttgat
    15301 gttgaataca agtactctaa gcaatcaggt ggtagaggac aatacggtca cgttaagatt
    15361 agagttgctc ctcaagagcc aggtgaagga tacaagttca caaacaaaac tgttggtgga
    15421 tcagtaccaa aagaatatgt tggtccagtt gacatgggta tacaaggagc tatgcaatct
    15481 ggtatagttg ctggatatcc agttgtagac gttgctgttg agttatatga tggttcttac
    15541 catgaggttg actcttctga gatggcgttt aagatggctg gttcaatggc attcaaagat
    15601 gctatgaaga aaggtaatgc agttctttta gagccttact tcaaagtaga agttgttact
    15661 ccagaagatt acatgggaga tgttatgggt gacttaaact caagaagagg attaatccaa
    15721 ggtatggaag ctagaagtgg tgcacaagtt ataaatgcat tcgttccact ttcagaaatg
    15781 tttggatact caacagacct aagatcttca actcaaggtc gtgcaactta cacaatgata
    15841 ttcgatcact atgagcaagt tccagcttca gttgctaaga aaatagctga aggaaaataa
    15901 tttaaaaata attaataata taaatataaa aaataatcag ctagatgaga tatatctcat
    15961 ctagcacaag at
//
LOCUS       DACTZW010000094        15713 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.094, whole genome shotgun sequence.
ACCESSION   DACTZW010000094 DACTZW010000000
VERSION     DACTZW010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15713
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.094"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            64..1020
                     /locus_tag="JAM15_15895"
     CDS             64..1020
                     /locus_tag="JAM15_15895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAT6799732.1"
                     /translation="MYILNLNTRETIEDFRDKFYVAENSYLILSAPKNLKLLKETLDI
                     DEITFNDCLKFDEITKLDLFDNYDFLSLNTFELRDGEAVIEEVNMYLSDNFILVVVNE
                     EHFLFEFVKNIILKNSQLEKNPVINLFKINYLILREVIKNGFESLEKVEELILQIEDE
                     MMDNINKNHVSRISDVRGLTRIIVKNTRPLLYIGDRIVKENIRYLKYSNVKKYNLENF
                     QGIDFGIDKLYNFALSTRELADKLLDIYSSRVGEKTNNLITKLTLLTAISAPLTIITG
                     IYGMNFRYMPELNWIYGYPATLFFMLCIIFVGIIIFKIKKLL"
     gene            1482..2495
                     /gene="aroF"
                     /locus_tag="JAM15_15900"
     CDS             1482..2495
                     /gene="aroF"
                     /locus_tag="JAM15_15900"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008680408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HAT6799733.1"
                     /translation="MIVVLKMGADKNEVKKLIEAIGREGVEVNPIDGTELTVLGLVGD
                     TSKIDAKRIEANKIVEKVMHVVEPFKKANRKFHPEPSIINVNGMEIGSKKIAMIAGPC
                     SVETEDQIVSIAKDVKKSGAGFLRGGAFKPRTSPYAFQGLKYDGLDLLKKAKEKTGLP
                     IVTEIMSTQDIDIFEENVDVIQVGARNMQNFDLLKELGKTNKTILLKRGLSATIEEWL
                     MSAEYIMAGGNENVVLCERGIRTFETYTRNTLDLSAILAVKKLSHLPVIVDPSHAAGK
                     SWMVDSLSKAAIAVGADGLIIEVHNDPAHALCDGKQSIKPNEYDELISELKTIASAVG
                     REI"
     gene            2517..3581
                     /locus_tag="JAM15_15905"
     CDS             2517..3581
                     /locus_tag="JAM15_15905"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HAT6799734.1"
                     /translation="MEEKLLVNLKENSYNIFIKKNILKNIGEEIKKIYFGNKIFIVTD
                     ENIAKLYLDKVKNNLSESGFEIKSLILKSGEETKSFNTLPKIYDSLLDFKLTRKDLII
                     TLGGGVIGDLGGFAAATFLRGISFIQIPTSLLAQVDSSVGGKVGVDLERGKNLVGSFY
                     QPKAVFIDPNVLLSLPEKFYRDGMAEVIKYGCIKDKTFFNKLLSLKNREEVMQHIEYI
                     IHKCCFIKKTVVEADEKDFGDRMLLNFGHTLGHAIEKYYNFTGYTHGEAVAIGMYKIT
                     LESEKIGITKKGTSELIKSILMNYNLPYEIELRDNKSIVDAISLDKKNLGDTLKIILL
                     KDIGESIIYNTTSKFFQEVR"
     gene            3581..4894
                     /gene="aroA"
                     /locus_tag="JAM15_15910"
     CDS             3581..4894
                     /gene="aroA"
                     /locus_tag="JAM15_15910"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008421733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HAT6799735.1"
                     /translation="MGSLKIYPSKLSGDVKIPPSKSMAHRAVICSSLSNGKSRISNID
                     FSDDIIATIRAMTSLGAIIEKKEDTLEISGIFSKEGILNRENQLNQPKLTIDCNESGS
                     TLRFLVPISLAFDGVKRFIGRGNLGKRPLDTYYEIFDRQNIKYSYKENQLDLIISGKL
                     KPDEFRVKGNISSQFITGLLFILPTLESDSKIIITTELESKGYLDLTLSTIKDFGVEI
                     INNNYKEFIIKGNQTYKARDYKVEGDYSQGAFYLSADAIGEDISILDLKEDSLQGDSE
                     VVEILSRMGMEILREGNKIKGITNGLNSTLIDASQCPDIIPVLSVVASLSIGRTTIIN
                     AGRLRIKECDRLHAINVELSKLGANIEEKEDSLIIEGVSKLNGGVEVWSHKDHRIAMT
                     LAIASCRCDKPIILKDFECVSKSYPHFFKDFKMLGGRIDEWNMGK"
     gene            4872..5951
                     /gene="aroC"
                     /locus_tag="JAM15_15915"
     CDS             4872..5951
                     /gene="aroC"
                     /locus_tag="JAM15_15915"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HAT6799736.1"
                     /translation="MSGIWGNNLKVSIFGESHGNAIGINIDGLPSGIELDLDKIDKEM
                     KRRAPGKNSISTSRNESDIPEILSGYFNGRTTGTPLCAIIRNSDTRSKDYGELKNLMR
                     PGHADFTGNVRYSGFNDYRGGGHFSGRITAPLVFCGAICKQVLSQKGIEIGAHIKKIK
                     NIEDMSFDYVNISKQQLSNLQTLELPLLDLSKEEAMKNTIIDAKNQRDSVGGIIECAV
                     VGINVGLGNPFFDSVESTLSHLLFSVPAVKGVEFGLGFELADMYGSQSNDEMYYEGNQ
                     VKSKTNNNGGIIGGITTGMPIIFKVAIKPTPSISRQQNTVNIKDKKDDILYIKGRHDP
                     CIVQRAIPVIEAVTAIGIFDLMKGR"
     gene            5954..7150
                     /gene="pheA"
                     /locus_tag="JAM15_15920"
     CDS             5954..7150
                     /gene="pheA"
                     /locus_tag="JAM15_15920"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HAT6799737.1"
                     /translation="MEDLTRYRNEIDNIDKELIQLFEKRMNTVLEIARHKMKNNTTIL
                     QKDREEKVLSRAVDNLDNKAYSQETVQFFNSIMEISRGLQKRLIDNDGEQKIEFSLDS
                     SNKKFDLSNVNKYKSLKDELNKKNILVGFPGKSGSFTEEALNKFFNKTISKKQFKEFE
                     DVFIALKNKEINYGIIPIENSSTGAISETYDLLRKYGFYIVGEECIKIDQNLIGIKDT
                     KLEDIKEIYSHPQGIGQCSEFLKQNSTWKLIPFNNTATSAELVRKLQDKTKAAIASKK
                     AASIYELEIISPCINDIANNYTRFVVISNQIHIEEESNKMSVVFSVEHEAGKLYKVLG
                     YFAENNINMTKIESRPMKNASWRYFFYIDFECSIYNSKVYDLLELIEHNTAYFKFMGV
                     YKNKTE"
     gene            7197..8006
                     /gene="aroE"
                     /locus_tag="JAM15_15925"
     CDS             7197..8006
                     /gene="aroE"
                     /locus_tag="JAM15_15925"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HAT6799738.1"
                     /translation="MNFFGLVGEKLSHSVSPQIHKRIFEILNIESAYKNFEIPKEDIS
                     KLDGAIKLLGIQGVNVTVPYKERIMKYLDFISPEAKRIGAVNTILLRENMLYGYNTDY
                     FGLDSMFKMANIDVQGKVAVILGTGGASKAALTYFIDSGIEKLYVSTRKKDDKKLLNS
                     KAILIDYEELKHIKGDIILNATPVGMYPNVGISPVSKSIIQNFDILIDLIYNPGETEF
                     LRIGNSMGKKTCDGLYMLVGQAIKSQEIWQDTKIDNSILDVIYNELKLEFL"
     gene            8018..8551
                     /locus_tag="JAM15_15930"
     CDS             8018..8551
                     /locus_tag="JAM15_15930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HAT6799739.1"
                     /translation="MINKTKEKLILIGMPGSGKTTIGKLLAKEYNCSFCDMDDYIIQI
                     SQKSIAELFSEGEDIFRNYETQACRELSISDKTVISTGGGVIKKDVNMEILKETGIII
                     FIDRPIQKILEDININSRPLLKNGKNRLYNLYNERINLYKKFSDIEILNDKSLNNAVY
                     NITNAVSENFKFDFKEK"
     gene            8572..9411
                     /locus_tag="JAM15_15935"
     CDS             8572..9411
                     /locus_tag="JAM15_15935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HAT6799740.1"
                     /translation="MNIVIVGLGVIGGSFAKALKKAGYENVFGVDVDLETLKKAEKAK
                     IIKKGCTTGKELFKKADLIILSIYPRLVVDFLNNNKNFFKKGTIITDTTGIKETLIND
                     VLQIIPDDIDFIFGHPMAGREKKGIDFASEQVFNGANYIITPTGRNNIKNLELVENLI
                     LEVGFKRVKKLTSQKHDEIIAFTSQLPHVMAVALINSDEEGRDTGKFIGDSYRDLTRI
                     ANMNEDLWSELFLGNRDNLLKVIENFESEVNLVKEAIFNNDKNKLIEYFKKSSIRREA
                     LEK"
     gene            9679..11160
                     /locus_tag="JAM15_15940"
     CDS             9679..11160
                     /locus_tag="JAM15_15940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HAT6799741.1"
                     /translation="MKKNRLIAKNISIAFIVLFFFSVFTFFYVGNINRVLEYETNDII
                     TVTIAGWIILSFLFLGIIIYILYSKANSQKTIEKVAYTDFVTGYSNWRKFELDVTNLL
                     KKTSQNNKYAMVIFDIDKFKAINDIYGHKKGNLILKDIADTLNELTNINETFARVSAD
                     NFNILLTYNKKEDIINIIKKIMANNELVNLSFGIYEIKDKDLSVSVYSDRASLAKSSI
                     KNNSDVNFAFFNDKLREKLLLEDKIEKEMEYALESGQFVMYLQPKYNIKLDKFCGSEA
                     LVRWQYTEKEVIYPSDFIPIFEKNGFIRKIDMYILEQACKEIQSLFDKGISPLPISVN
                     FSRVDFFKKDFIENIVNICDRYKIPYSLIEIEITESSMFGDTDTLFNVSRNLQDIGFI
                     VAMDDFGSGYSSVNMLKNIPLNVIKLDRGFFVDDKDVDKSQIVIKSIVSLIKQLGIRV
                     VAEGIETRSQIEMLKKTNCDIVQGYYFSKPLPIKEFEKLVYKI"
     gene            11193..14630
                     /locus_tag="JAM15_15945"
     CDS             11193..14630
                     /locus_tag="JAM15_15945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HAT6799742.1"
                     /translation="MIRAKSLKNVLSIVLIFLFTIISFSDFAFKTNVQEEENSKINLR
                     EISLQSSNAIKIKLDNSLSFIKSVANMVSYFNTIDNSKIVPLLANISKESDFQRISIV
                     SPDGISHTSDGKIINVSNYQYFKKAIKGESNISEVVKSPIDGKDIFVIATPVFNKNNK
                     IIGVLYGSYYNDKLAEFIDITSFNSEGYIDIFESSGQFVLKSSHTNKLIKSSSNIYDI
                     FKKASFDDGYSYKKIYEDTKNNKSGFTSYEYKGENRYATYTPIGVNDWYVISVIPQYT
                     VRRNIDKINQLAFSLIFKVFLLFIILIIYIIYKNNKSQKDILKANKEISSITNSIPGG
                     VQKCTLGETCNINFLSDGFIELFGYTREEIKTLFNNDFYSLIHKDDVERIKKEISKQL
                     YKNKTIELEYRIITKNGNTVWVLDKGELITEPDGEEYFCCVTVDITRTKQLEQEMEQK
                     NLELEMISENILGGIIITEFNDDFTIKYTNSGYLSMIGYTREQLENELKYKASNLVFY
                     EDRKKALESIQHQLNTKRIAVYQHRIRKRDGNIIWVSIKGRLIIDDDGIEKGIWILND
                     ITDLKNAEQKLKINEERFRVALKQTSNTIFEYDIKTKSLLNTSKELDKYNIYKITKNV
                     PYSLVESGVIHKDFSDDFINMYENVTNGAKKASCVVKMKLPDENYIWNKVTLTTIFDE
                     YGNPVRAIGIQEDISKQKEAEIRYNQEGKYHSAILSEAMITYEINVSKDTFIKGNENW
                     QKPFGIKPDNNYSQMVKIISNTIVHKDDKETFLNTFLCENLLDAYKNNVTEIKLEYRR
                     MNQENKMIWVVCTMHLIKDSVTNDIKALAYVKDIDKQKNEEIRLKLKAERDTLTGLYN
                     KGTTEKLINDFLNSEEASLGMHAFLIVDIDNFKSVNDNLGHVFGDKVLFEVSKNLKPI
                     FRIDDIVGRIGGDEFIVFLKNIQSFENAKKKAEKICDIFRNSYTENKKTYKISGTVGI
                     SFVPEHGTVFEELYKKADIALYYAKSKGKDKYALYNDCIYQNELENNISDNNIKLADK
                     CEKSKPVLKEILDSIDNYIYIVNPNTYELLFVNNKVSRLDLEIKLGETCYKSLLKSDR
                     PCNNCPLNGLEENKHSKFKIETNTFGKNISIASWINCIDGEYNCLIECIDSSLYKNK"
     gene            14648..15394
                     /locus_tag="JAM15_15950"
     CDS             14648..15394
                     /locus_tag="JAM15_15950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HAT6799743.1"
                     /translation="MLNSITLILGIIFTIYYFYLKIVFGGISFSEIFLVVGIVLIIYQ
                     IFKKKIKEKKVFYRVLKIIISIFLIVFVVTESLIIFYPKNSLESKSDYLLILGASVKK
                     TTPSTTLKGRLDTALKYLKINDNCYVVVSGGKGSREKITEAKAMKDYLIKNGIDKNRI
                     IEEDKSTNTYENFKYSKLKIEEHSQRKLSDLKVKIVTTDFHVLRSKILAYRNGYKNTS
                     FYASKSKLSFVPTYYTREFFALWKTIIFDR"
     gene            complement(15343..15663)
                     /locus_tag="JAM15_15955"
     CDS             complement(15343..15663)
                     /locus_tag="JAM15_15955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799744.1"
                     /translation="MKKIMNFLKENSTFYFATVEDNKPRVRPFGFIMDYEGKLYFGIV
                     KYKTSYKQLLVNPNVEISTTSKVGKWIRIKGIEKTRYEFISSLFIYYLSKMIVFHNAK
                     NSLV"
BASE COUNT         6506 a         1533 c         2596 g         5078 t
ORIGIN      
        1 aataattaca gtaatgatta taaaaaattt ttagaatgta aattgaaatt taggagtaga
       61 tgtatgtata tactgaattt aaatacaaga gagactattg aagattttag agataaattt
      121 tatgtagcag aaaattctta tcttatatta agtgctccaa aaaatttaaa attgcttaag
      181 gaaactttgg atatagatga aataactttt aatgattgtc ttaaatttga tgaaataacc
      241 aaacttgatt tatttgataa ttacgatttt ttaagcctaa atacatttga actaagagat
      301 ggagaagctg ttatagaaga ggtaaatatg tatttatcag ataattttat attggttgta
      361 gtgaatgaag aacacttttt atttgaattt gtaaaaaata ttattttgaa gaactctcaa
      421 cttgaaaaaa atccagttat taatctattt aagataaact acttgattct tagagaagtt
      481 ataaaaaatg gttttgagtc tttggaaaaa gttgaagagt taattcttca aatagaagat
      541 gaaatgatgg acaacattaa taagaatcat gtatctagaa taagtgatgt aagaggatta
      601 acaagaatta tagttaagaa tactagacct cttttgtata ttggggatag aatagttaag
      661 gaaaatataa gatatttaaa atattcaaat gtaaaaaaat ataatttaga aaattttcaa
      721 ggtatagatt ttggaattga caaattatac aatttcgcat tgtcaacacg agagttagca
      781 gataaattat tagatattta ttcttccaga gtaggtgaga aaacaaataa cttaattaca
      841 aaattaacct tgttaacagc catatcagca ccacttacaa ttataactgg tatatatgga
      901 atgaacttta gatatatgcc agaattaaac tggatttatg gatatccagc aactttattt
      961 tttatgctat gtataatttt tgttggaatt ataatattta aaataaaaaa attattgtaa
     1021 attacagatg atgtttaatt gattttataa aaatacatca attgagaagc tgatttaagt
     1081 aaataaaaaa atattttaaa ttgaaaatat ttatagaaaa tattgacaat tatattttct
     1141 ttgttataat tattaaacaa gaagaataat aaattataaa aatggaggat aatactatga
     1201 aaggaatatt aaaagaacta acagcaaaac tttatagctt tttttacttt atgttctggg
     1261 gcttttattt tagcgctggc tatttctttt acaaaaatat atgtacttcc tttctggtga
     1321 ggccttattt tagtgatttt gagcataagt aaattttata aaaatgatta ttttatatat
     1381 ttatataaga tttagtgctt gatagattat tttagagaac tcattagtga gttctctttt
     1441 ttattttaaa tataaaatta taatattggg aggtagtaaa aatgatagta gtattaaaaa
     1501 tgggagcaga taaaaatgaa gttaaaaaat taattgaggc tattgggaga gaaggagtag
     1561 aagttaatcc catagatgga acagaattaa ctgttttagg tttagttgga gatactagta
     1621 aaatagatgc caaaagaata gaagcaaata agatagttga aaaagttatg catgtagtag
     1681 agccttttaa aaaggccaat agaaaatttc atccagaacc ttcaatcata aatgttaatg
     1741 gaatggaaat tggttcaaag aaaattgcta tgatagctgg gccttgttct gttgaaacag
     1801 aagaccaaat agtatctata gctaaagatg tgaaaaaatc aggtgcagga tttttgagag
     1861 gtggagcatt taaaccaaga acatcaccat acgctttcca aggattgaaa tatgatggat
     1921 tggatttatt aaaaaaagca aaagaaaaaa cagggcttcc tatagttaca gaaataatgt
     1981 caacacaaga tatagatata tttgaagaaa atgtagatgt aattcaagtt ggagctagaa
     2041 acatgcagaa ctttgattta ttaaaagaat taggtaaaac aaataaaaca atacttttaa
     2101 aaagaggatt atctgctaca attgaagagt ggctaatgtc agcagagtat ataatggctg
     2161 gaggaaatga aaatgtagtt ctttgtgaaa gaggtataag aacttttgaa acatatacta
     2221 gaaatacttt ggatttaagt gcaattttag ctgtgaagaa acttagtcat ttaccagtta
     2281 tagttgaccc aagtcatgca gcaggtaaat catggatggt tgactcttta tctaaggcag
     2341 caattgcagt tggagcagat ggtctaataa tagaagttca taatgaccca gcacatgcac
     2401 tttgtgatgg aaaacaatcg attaagccaa atgaatatga tgaattgata agtgaattaa
     2461 agactatcgc atcagcagtt ggtagagaaa tataatctat aaaaggatgg ttaaacgtgg
     2521 aagaaaaact attagtaaat ttaaaagaaa atagctacaa tatatttatt aaaaaaaata
     2581 tactaaagaa tataggagaa gaaataaaaa aaatatattt tggaaataag atttttattg
     2641 taactgatga aaatatagca aaattatact tggataaagt aaaaaataat ttaagtgaat
     2701 ctggatttga aattaaatct ttaatattaa aatctggtga agaaacaaaa tcatttaata
     2761 ctcttcctaa aatatacgat agtttacttg actttaagtt aactagaaaa gatttgatta
     2821 ttactttagg aggaggggta ataggtgatt taggtggatt tgcagcagca acttttttaa
     2881 gaggtataag ttttattcaa attccaacat ctttattagc acaagttgat agttctgtag
     2941 gtggaaaagt tggagttgac cttgagagag gcaaaaattt agtgggaagc ttttaccaac
     3001 caaaagctgt gtttatcgac ccaaatgtat tattatcact tccagaaaaa ttctatagag
     3061 atggaatggc agaagttata aaatatggat gtataaaaga caaaactttt ttcaataaac
     3121 ttttaagttt aaaaaataga gaagaagtaa tgcaacatat agaatacatt atacataaat
     3181 gttgctttat taaaaaaact gtagttgaag ctgatgaaaa agactttgga gatagaatgc
     3241 ttctaaactt tggccataca ttaggtcatg ctattgagaa atactacaat tttacgggtt
     3301 atacccatgg agaagctgtt gccataggaa tgtataagat aactttagaa agtgaaaaga
     3361 taggaattac aaaaaaaggt acatcagaac ttataaaatc aattttaatg aattataatt
     3421 tgccttatga gattgaatta agagataata aatctatagt agatgctata tctcttgata
     3481 aaaaaaatct aggtgataca ttaaaaataa tacttttaaa agatattgga gagagtatta
     3541 tatataatac tacttctaaa ttttttcagg aggtaagata atgggaagtc taaaaatata
     3601 tccaagtaaa ttatctggag atgtaaaaat accaccatca aaaagtatgg cacatagggc
     3661 agttatttgt tcatctctaa gcaatggaaa aagtagaatt tctaatatag atttttctga
     3721 tgatataata gctactataa gagcaatgac atcattagga gctattatag aaaagaaaga
     3781 agatacttta gaaatttcgg gaattttttc taaagaaggt attttaaata gagagaatca
     3841 gttgaatcaa cctaaattga caatagattg taatgaatca ggctctacat taagattttt
     3901 agtacctata tctttagcat ttgatggtgt aaaaaggttt ataggtagag gtaatcttgg
     3961 aaaaagacca cttgatactt attatgagat atttgacaga cagaatataa aatatagtta
     4021 caaagaaaat cagttagatt tgattatatc aggtaagctt aaaccagatg aatttagagt
     4081 aaaaggaaat ataagttctc agtttatcac aggtctattg tttatattgc ctacactaga
     4141 gagtgattca aagataataa ttactactga gctagaatct aaaggatatt tagatttaac
     4201 tctttcaacg ataaaagatt ttggggtaga aattataaac aataactata aagaatttat
     4261 tataaaagga aatcaaacgt ataaagcgag agattataaa gtagaaggag attattctca
     4321 aggagcattt tatttatcag cagatgctat aggagaagat attagcatat tagaccttaa
     4381 agaagattct cttcaagggg atagtgaagt agttgaaatt ttatctagga tgggaatgga
     4441 aatattaaga gaaggcaaca aaataaaagg aataacaaat ggtttaaata gtactttgat
     4501 agatgcatct caatgcccag atataatacc tgtattatct gtagtagcat ccttaagtat
     4561 agggaggact acaataatta atgctggtag gcttagaatt aaagaatgtg atagacttca
     4621 tgcaataaat gttgagttaa gtaaacttgg agcaaatata gaggagaaag aggatagttt
     4681 gataatcgaa ggagtaagca agttaaatgg tggagtagag gtgtggagtc acaaagacca
     4741 tagaattgct atgacacttg caattgcttc ttgtagatgt gataaaccaa taatattaaa
     4801 agattttgag tgtgtatcaa aatcttatcc acattttttt aaagatttta agatgttagg
     4861 aggtcgaatt gatgagtgga atatggggaa ataatttaaa agtatcaatt tttggagaat
     4921 ctcatggaaa tgctataggt ataaatatag atggtcttcc ttcagggatt gaacttgacc
     4981 ttgataagat tgataaagaa atgaagagaa gagcacctgg aaaaaattct atatctactt
     5041 caagaaatga aagtgatata ccagaaattc taagtggata ttttaatgga agaactacag
     5101 gaacgccatt atgtgcaatc ataagaaata gtgatactcg ttcaaaagat tatggagagc
     5161 ttaaaaattt aatgagacca ggacatgcag atttcacagg taatgtgaga tattctggat
     5221 ttaatgacta tagaggggga ggtcattttt caggtaggat aacagctcca ttagtatttt
     5281 gtggggctat atgtaaacaa gttttatcac aaaaaggaat agagatagga gcacacataa
     5341 aaaaaattaa aaatatagaa gatatgagtt ttgattatgt aaatatttca aaacaacagt
     5401 tatcaaattt gcaaactttg gaactacctt tacttgattt atcaaaggaa gaagccatga
     5461 aaaatacgat tatagatgca aaaaatcaaa gagattcagt tggtggtata attgaatgtg
     5521 cagtagtagg tattaatgta gggcttggaa atccattttt tgactctgtt gaatctactt
     5581 tatcacattt attgttttct gttcctgccg taaaaggtgt agagtttggt ttaggttttg
     5641 aacttgcaga tatgtatggc tctcaaagta atgatgaaat gtattatgaa ggaaatcaag
     5701 ttaagagcaa aacaaataac aatggaggga ttataggagg gattactact ggaatgccaa
     5761 taattttcaa agtggcaatt aagccaactc cttcaattag cagacaacaa aacacagtta
     5821 atataaaaga taaaaaggac gatattttat atattaaagg cagacatgac ccttgtatag
     5881 ttcaaagggc tatacctgta atagaagcag taacagccat tggaattttt gatttgatga
     5941 aaggacgata ataatggagg atttaacgag atatagaaat gagattgaca atatagataa
     6001 agagcttatt caattatttg aaaagagaat gaatacagtt cttgaaattg ccagacataa
     6061 aatgaaaaat aacactacta tacttcaaaa agatagagaa gaaaaagtac taagtagagc
     6121 cgtagataat ttagataata aagcatattc acaagaaacg gtacagtttt ttaattctat
     6181 aatggaaatt agtagaggat tacaaaaaag attgatagat aatgatggtg agcagaaaat
     6241 cgagtttagt ttagattcat caaataagaa atttgatttg tcaaatgtaa ataaatataa
     6301 gtctttaaaa gatgaattaa ataaaaaaaa tatcctagta gggtttccag gaaaatcagg
     6361 ttcatttaca gaagaagcac taaataaatt cttcaacaaa acaatatcaa aaaaacaatt
     6421 taaagaattt gaagatgttt tcatagcact taaaaataaa gaaataaact atggaataat
     6481 ccccatagaa aattcatcta caggagctat ctctgaaact tatgaccttt tgagaaagta
     6541 cggtttttat atagttggag aagaatgtat aaaaatagac caaaatttaa tagggataaa
     6601 agacacaaaa cttgaagata taaaagaaat atattctcat ccacaaggta taggacaatg
     6661 tagtgaattt ttaaaacaaa atagtacatg gaaattgata ccatttaata acacagcaac
     6721 aagtgcagaa cttgtaagaa aacttcaaga taaaacaaaa gcagcaattg caagcaaaaa
     6781 agctgcaagt atttatgaat tagaaataat aagtccttgt ataaatgata ttgcaaacaa
     6841 ctatacaaga tttgtagtaa tcagtaatca aatacacatt gaagaagaat caaataaaat
     6901 gagtgtagta ttttctgttg aacatgaagc aggaaaactt tataaagtac ttggatactt
     6961 tgctgaaaat aatataaata tgacaaaaat agaatcaaga cctatgaaaa atgcctcatg
     7021 gagatatttc ttttatatag attttgagtg ttctatatac aattctaaag tgtacgactt
     7081 attagaattg atagaacata atacagcata ttttaaattt atgggagtat ataaaaataa
     7141 aactgaatag ataatataaa tttttattta atttataatt attaggaggt gtaagtatga
     7201 attttttcgg tctagtaggt gaaaaactct ctcacagtgt ttcacctcaa atccacaaga
     7261 gaatattcga gatattgaat attgaaagtg cttataaaaa ctttgaaatt ccaaaagaag
     7321 atatatctaa gctagacggt gctataaaat tattaggaat acaaggagta aatgttactg
     7381 taccatataa ggagcgtatt atgaaatatc ttgattttat atcaccagag gcaaaacgta
     7441 taggagcagt taatacaatt ttactcagag aaaatatgtt atatggttac aatacagatt
     7501 actttggtct tgatagtatg tttaaaatgg ctaatattga tgttcaagga aaagtagcag
     7561 ttatattagg aactggaggt gcttctaaag ctgctcttac atattttatt gattctggta
     7621 tagaaaagct ttatgtttca actagaaaaa aggatgataa aaaattatta aatagtaaag
     7681 ctatattaat agattatgaa gaacttaaac atataaaagg agatataata ttaaatgcta
     7741 caccagtagg tatgtaccct aatgtaggaa tttcaccagt gtcaaaatct attatacaaa
     7801 attttgatat attaatagat ttaatttaca atcctggaga aacagagttt ttaagaattg
     7861 gtaatagtat gggtaaaaaa acttgtgatg gattatatat gctggtaggg caagcaataa
     7921 aatctcagga aatttggcaa gatactaaaa tagataatag tattttagat gttatatata
     7981 atgaactaaa attagaattt ttgtaaggga gattgttatg ataaataaaa caaaagaaaa
     8041 attgatatta ataggtatgc caggtagtgg aaaaactaca attggtaaac ttttggccaa
     8101 agaatataat tgtagtttct gtgatatgga tgattatata attcaaatat ctcaaaaaag
     8161 tatagcagag ttgttttcag aaggagaaga tatctttagg aactatgaga ctcaagcatg
     8221 tagagaactt tctataagtg ataaaacagt gatatctaca ggtggaggtg taataaaaaa
     8281 ggatgttaat atggaaatac taaaagaaac aggtataata atttttattg atagacctat
     8341 acaaaagatt ttggaagata taaatattaa ttcaagacca ttattaaaaa acggaaaaaa
     8401 tagattgtat aatctttata atgagagaat aaatctttat aaaaaatttt cagatataga
     8461 gattttaaat gataaatcat taaataatgc tgtatataat attacaaatg cagtcagtga
     8521 aaattttaaa tttgacttta aagaaaaata atctaggggg aaataaaaat aatgaatatt
     8581 gttattgtag gactaggagt tataggaggc tcttttgcta aagcattaaa aaaagctgga
     8641 tatgaaaatg tatttggagt agatgtagat ttagaaactt taaaaaaagc agaaaaagca
     8701 aaaatcataa aaaaaggatg tactacaggt aaagagttat ttaaaaaagc tgatttaatt
     8761 atactatcta tatatcctag attagttgta gattttctaa ataataataa aaactttttt
     8821 aaaaaaggga ctataattac tgatactaca ggaataaaag aaacacttat caatgatgtg
     8881 ttgcaaatta ttccagatga tatagatttt atatttggac atccaatggc aggtagggaa
     8941 aaaaagggta ttgattttgc aagtgaacaa gtttttaatg gcgcaaatta tataattact
     9001 ccaactggca gaaacaacat aaaaaattta gagttagttg aaaatttaat tttagaggtt
     9061 ggatttaaaa gagtaaaaaa gttaacttca caaaaacatg atgagattat agcttttact
     9121 tctcagttac ctcatgttat ggcagttgct cttataaata gtgatgaaga aggtagagat
     9181 acgggtaaat ttattggaga tagttataga gatttaacta gaattgcaaa tatgaatgaa
     9241 gacttatgga gtgaactttt tttaggaaat agagataatt tactaaaagt tatagaaaac
     9301 tttgaatcag aagtaaattt agtaaaagaa gctatattta acaatgataa aaataaatta
     9361 atagagtatt ttaaaaaatc atcaataaga agagaagctt tagaaaaata aatattaata
     9421 tttaagctat atatagatgg gtataaatat aagcgatagt gtatttaatt gtattaataa
     9481 atatggattc aatataatta aatatgctat tgatatattt gtacccttaa ctattgttat
     9541 cttttaaatg ataatgatat ttatttaaat actctttatt aacaatttat aaaacttaat
     9601 tgtaaaaaat acttattaat agtaaaataa agtgaatcaa ttatattata attgctaaag
     9661 agagtgaggt gtagctattt gaaaaaaaat agattaatag caaagaatat atcaatagca
     9721 tttatagtac tattcttttt tagtgtattt acattctttt atgtaggtaa tattaataga
     9781 gtgttagaat atgaaacaaa tgacataata acagttacaa ttgctggatg gattatactt
     9841 tcatttttat ttttaggtat tataatttac atattatatt caaaagcaaa tagtcaaaaa
     9901 actatagaaa aagtagcata tacggatttt gtaacaggtt attccaactg gagaaagttt
     9961 gaattagatg ttacaaattt attaaagaaa acatcacaaa ataataaata tgcaatggtc
    10021 atattcgata ttgataaatt taaagcaatt aatgatatat atggccataa aaagggaaat
    10081 ttaatattaa aagatattgc agatacttta aatgaattga ctaatatcaa tgaaactttt
    10141 gctcgtgtaa gtgctgataa ttttaatata ttattaacat ataacaaaaa agaggatata
    10201 ataaatatta tcaaaaagat tatggcaaat aatgaacttg taaacttatc ttttggaatt
    10261 tatgaaatca aagataagga tttatctgta agtgtatata gtgatagagc ttcacttgca
    10321 aaatcatcaa taaaaaataa tagtgatgta aattttgcat tttttaatga taaattaaga
    10381 gagaaattat tacttgaaga taagatagaa aaagaaatgg aatatgctct tgaaagtggg
    10441 caattcgtaa tgtatttaca accaaaatac aatattaaat tagataagtt ttgtggaagt
    10501 gaagccctag tcagatggca atacacagaa aaagaggtca tatatccaag tgattttatt
    10561 cctatatttg aaaaaaatgg atttattaga aagattgata tgtacatatt agaacaagct
    10621 tgtaaagaaa tccagtcttt atttgataaa ggaatttcac ctttacctat atctgtaaac
    10681 ttctcaagag ttgatttttt taaaaaagat tttattgaaa acatagtaaa tatatgtgat
    10741 agatataaaa taccatatag tttaatagaa attgaaatta ctgaatctag tatgtttgga
    10801 gatactgata ctctatttaa tgttagtaga aacctacagg atattggctt tatagttgca
    10861 atggatgatt ttggctcagg atattcttct gtaaatatgc ttaaaaatat accattaaat
    10921 gtaataaaat tagatagagg attttttgtt gatgataaag atgttgataa gagtcaaatt
    10981 gttataaaaa gcatagtttc tctcattaag caattaggaa taagggttgt tgctgaagga
    11041 attgaaacaa gaagtcaaat agaaatgtta aaaaaaacaa attgtgatat tgttcaagga
    11101 tattattttt caaaaccatt accaattaaa gaatttgaaa aattagtcta taaaatatag
    11161 tcagtgagtc ttaaatggga ggtggtgatt aagtgataag agcaaaatcg ttaaaaaatg
    11221 tactgagtat tgttttaata tttttattta caataatttc tttttctgat tttgcattta
    11281 aaactaatgt ccaggaagaa gaaaatagta aaattaattt aagggaaata tccctacaaa
    11341 gttccaatgc tataaaaata aaattagata attctctatc ctttattaaa agtgtggcaa
    11401 atatggtttc ttattttaat actatagata actcaaaaat agttccatta ttagctaata
    11461 tatcaaaaga atctgatttt caaagaatat ctattgtatc tcctgatgga ataagtcata
    11521 ccagtgatgg caaaattatc aatgtgtcaa attatcaata ttttaagaaa gctattaaag
    11581 gagaaagtaa tatatctgaa gttgtaaaat ctccaattga tggaaaagat atttttgtta
    11641 tagctactcc tgtatttaat aagaataaca aaataattgg tgttttatac ggttcttact
    11701 acaatgataa attagctgaa tttatagata taacaagttt taatagtgaa gggtacatag
    11761 atatatttga atctagtggt caatttgttt taaaatcttc acatacaaac aaactgatta
    11821 agtcaagtag taacatatat gatatattta aaaaagcttc ttttgatgat ggttatagct
    11881 ataaaaaaat atatgaagat acaaaaaata acaagagtgg ctttacctca tatgaataca
    11941 aaggagaaaa tcgttatgct acttatacac ctattggtgt aaatgactgg tatgtaattt
    12001 ctgtgatacc acaatatact gtaagaagaa acattgataa aataaatcaa ttagcatttt
    12061 ctcttatttt caaggtattc ttattgttta ttatacttat aatatatatt atttataaaa
    12121 ataataaatc tcagaaagat atactaaaag ctaacaaaga aatttcatct attacaaata
    12181 gcattcctgg aggagtgcaa aagtgtaccc tgggtgaaac atgcaatatt aattttttaa
    12241 gtgatggatt tatagagttg tttggttata caagagaaga aataaaaaca ttgtttaata
    12301 atgattttta tagtttaata cataaagatg atgttgaaag aataaaaaaa gaaatttcta
    12361 aacaacttta caaaaataaa actattgaat tagaatatag aattataaca aaaaatggta
    12421 atacagtatg ggttttagat aagggagagc ttataacaga acctgatgga gaagagtatt
    12481 tttgttgtgt aactgtagat attactagaa caaaacaatt agaacaagag atggaacaaa
    12541 aaaatctaga acttgaaatg atatcagaaa atattttagg tggtataatt ataacagaat
    12601 ttaatgatga ttttactata aaatacacta actctggtta tctttcaatg attggatata
    12661 cacgtgaaca attagaaaat gaacttaaat acaaagctag taatcttgtt ttttatgagg
    12721 atagaaagaa ggctcttgaa agtatacaac atcaattaaa cacaaaaaga atagctgtat
    12781 atcaacatag aataagaaaa agagatggta atattatctg ggtttctata aaaggaaggc
    12841 ttattattga tgatgatggt attgaaaaag gtatttggat tctaaatgac ataacagatt
    12901 taaaaaatgc agaacaaaaa cttaaaataa atgaagaaag atttagagtt gcattaaagc
    12961 aaacatcaaa cactatattt gagtatgata taaaaacaaa atcactttta aatactagta
    13021 aagagcttga taaatataat atttataaaa ttactaaaaa tgttccatat tctttagtag
    13081 aatcaggagt tattcataaa gattttagtg atgattttat aaatatgtat gaaaatgtaa
    13141 caaatggagc aaaaaaagca agttgtgtag ttaagatgaa acttccagat gaaaattata
    13201 tatggaataa agttaccttg actactattt ttgatgaata tggtaatcct gtaagagcaa
    13261 ttgggataca ggaagatata agcaaacaaa aggaagcaga aataagatac aatcaagaag
    13321 gtaagtatca ttcagctata ttgtcggaag caatgataac ttatgaaata aatgtatcaa
    13381 aggatacttt tatcaaagga aatgaaaatt ggcaaaaacc atttggaatt aagcccgaca
    13441 ataactattc tcaaatggta aaaattatat caaatactat tgtacataaa gacgataaag
    13501 aaacattttt aaatacattt ttatgtgaaa acctattgga tgcatataaa aataatgtaa
    13561 ctgaaataaa attagaatat cgaagaatga atcaagaaaa taaaatgatt tgggtcgttt
    13621 gtacaatgca cttaataaaa gattctgtta cgaacgatat aaaagcactt gcttatgtta
    13681 aagatattga caagcaaaaa aatgaagaaa ttagattaaa attaaaagct gaaagagata
    13741 ctcttacagg attatataat aaaggtacta cagaaaaatt gattaatgat ttcttgaact
    13801 ctgaggaagc aagcttagga atgcatgcat ttttaattgt tgatatagat aattttaaat
    13861 ctgtgaacga taatttagga catgtatttg gagataaagt attatttgaa gtttctaaaa
    13921 acctaaaacc tatatttaga atagatgata tagtaggtcg aattggtgga gatgaattta
    13981 tagtattctt aaaaaatatt cagtcttttg aaaatgccaa aaagaaagca gaaaaaatat
    14041 gtgatatatt tagaaattct tatacggaaa ataaaaagac atataaaata tctggaacag
    14101 ttggaatttc atttgtacca gaacatggaa ctgtatttga agaactttat aaaaaagcag
    14161 acatagcact ttattatgca aagagcaaag gaaaagataa gtatgcactt tataatgatt
    14221 gtatctacca aaatgaactt gaaaataata taagtgataa taatataaaa ttagcagata
    14281 aatgtgagaa atccaaacca gtacttaaag aaattcttga ttctattgat aattatatct
    14341 atatagtgaa tccaaatact tatgaacttc tttttgtcaa taataaggtg tctcgtttgg
    14401 atttagagat aaaattagga gaaacctgtt ataaatcact attaaaatct gatagaccat
    14461 gtaataattg ccctcttaac gggttagaag aaaataagca ttcaaaattc aaaatagaga
    14521 caaatacatt tggtaaaaat atcagtatag caagttggat taattgcata gatggagaat
    14581 ataactgtct tatagagtgt atagattctt ctttatacaa aaataaataa aaaaggacta
    14641 tgaaggtatg ttaaatagta taactttgat acttggtata atatttacga tttactattt
    14701 ttatctcaaa atagtttttg gaggaatttc atttagtgag attttcttag ttgtaggaat
    14761 tgtactaatt atatatcaaa tatttaagaa aaaaatcaaa gaaaagaagg ttttttatag
    14821 agtgttaaaa ataataatca gcattttttt aatagtattt gtagttactg agagtctaat
    14881 tattttttat cctaaaaata gtttagaatc aaaaagtgat tatctcttaa ttttaggagc
    14941 ttctgtaaaa aagactacac caagtacaac cctgaagggt aggttagaca ctgcattgaa
    15001 atacctaaaa attaatgata attgttatgt ggtagtatct ggtggtaaag gaagtagaga
    15061 aaaaataact gaggcaaaag ctatgaaaga ttatcttata aaaaatggta tagataaaaa
    15121 taggataata gaagaggata aatccacgaa tacttatgag aattttaaat attcaaaatt
    15181 gaagatagaa gaacatagtc aaagaaaact aagcgattta aaagtaaaaa tagtaacaac
    15241 agattttcat gttctcagaa gtaaaatatt agcatataga aatggatata aaaatacgtc
    15301 tttttatgct agtaaatcaa aactttcatt tgtaccaact tactatacaa gagaattttt
    15361 tgcattatgg aaaacaatca tttttgatag ataataaata aaaagactag atataaactc
    15421 atatctagtc ttttctattc ccttaattct aatccatttt ccaactttac ttgttgtaga
    15481 aatttcaaca ttgggattta caagtaattg cttataagaa gttttatatt ttacgattcc
    15541 aaaatataat tttccttcat aatccattat aaatccgaat ggtcttactc ttggtttatt
    15601 atcttcaact gtagcaaaat agaatgttga gttttctttt aaaaaattca ttattttttt
    15661 catgattaaa tcctctttgt atcttatact aatataatga atataaataa aat
//
LOCUS       DACTZW010000095        15621 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.095, whole genome shotgun sequence.
ACCESSION   DACTZW010000095 DACTZW010000000
VERSION     DACTZW010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15621
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.095"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(27..2051)
                     /locus_tag="JAM15_15960"
     CDS             complement(27..2051)
                     /locus_tag="JAM15_15960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAT6799745.1"
                     /translation="MDKKKLILITYDKLNSDHYKEELTNFFGDEIIIETQNILDGIKE
                     NLEGEVVLSLSPLTSNFLIKHFKEDIEIIHGTKALSKLGYEKMMKLPPGTKSLLMTTN
                     KTSAFEMATYLYKIGINHIDFVPTYPDCDEIYDLDTAITPGQIRFIPKYIKNIVDLGW
                     RKISLDTYMSLLVVLKLKNEKFIEKLYKLSKETLSHDFLNTSLDNISKLKTILYMTID
                     EIGDGLIFFNTFNKVTFVNKSLLNMLELDEKLIKSPSLMEYMPKSFLDKITKNLNIDN
                     MIIYIDEIDKKFILSKKPFYLYKNIEGCLITLKDVNNIEILEQKIRSDSVKRGYVAKY
                     KFNNIIGNSSIIKDCIKKAKKMALTDNPILITGETGTGKEAFTQSIHNHSNRKNKPFV
                     AINCASLPSELLESELFGYEDGSFTGAKKGGKKGLFELAHTGTIFLDEIGDMPHDLQV
                     KLLRVLQEKEIRKIGGTSIIPIDVRILAATNKDLEKLIIENKFRMDLFYRISMFTLDL
                     PPLRKRLEDIPLLLESFLKELPYKNIKLDKSLLEALNSYTWMGNIRELRNCVEYMAYM
                     GSNYLTINDLPQNISSKLNNNHMSSNMSIFNDLSQYDKNICISILKSLHMKPMGRTKL
                     MKFMEYNVTEYEVRNMLEYLTRNGYLISSKGRKGSSITEKGIKIIKNNII"
     gene            2441..3109
                     /locus_tag="JAM15_15965"
     CDS             2441..3109
                     /locus_tag="JAM15_15965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799746.1"
                     /translation="MSKLESTTEKVEVKWYGYVALILGALFFSGIFKDAPGPLKVLDF
                     NNVLGSFGTLGTINDGVGTLASNFRGDGGTGPRDGWLYALTLIPSVMFALGVVRVIDH
                     LDGMKAAQKLLSPLLKPLLGLPGFAGLTLIASLQSTDAAASMTKELKDDGYIDEKQKA
                     VFCAFQFSGASAITNFFASGAALFPFIGDVPIFIPLALILIMKFVGANLLRLYLNKFD
                     KGEA"
     gene            3111..3596
                     /locus_tag="JAM15_15970"
     CDS             3111..3596
                     /locus_tag="JAM15_15970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799747.1"
                     /translation="MSEVAKKEVKVKKGNVIDAFIGGARNGFQISTNSMAPNVIFGFA
                     IISVFNLTGLLDVIGTIFTPVMSIFGLPGVAATAIMTIFISMGGASGVIAGLFTAGQI
                     SQAHVAILLPMLLLSGAQIQFMGRLLGTAELKTKYYPHMFVIATLNGCIAMLIMNYFV
                     V"
     gene            3657..4778
                     /locus_tag="JAM15_15975"
     CDS             3657..4778
                     /locus_tag="JAM15_15975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HAT6799748.1"
                     /translation="MGTNKDYIEYVHKVYDYLHTIPEKGFEEYKTSEFVLKELEKMGF
                     ENINKGAAGTGIIVTIDSKKEGPVFAIRADMDALEFIIDGEKKMIHACGHDGHTSMLL
                     TAAKLIKERNLVKRGKLKILFQPGEEKLYGALRVIDSGLLDDVEEMVGMHLRPGQDCR
                     LGKAIPAMYHCASCIMQFTIKGITCHGSKPHLGVNAVDAVCLAVNAINAIRVNPAIPN
                     SIKVTNISVKGETYNNIPDEAFMALDIRAESNDIIEELKEKAIHAVKTAVSSINAEAV
                     LISKDGVPAAEFDEELVNLAEETIKDVLGADASIGIFKNSGGEDFHYYTQKLKCKTTY
                     IGLGADATPGFHNPNVTFDTKALEYGVDIWCRLVEKRLG"
     gene            5058..6248
                     /locus_tag="JAM15_15980"
     CDS             5058..6248
                     /locus_tag="JAM15_15980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAT6799749.1"
                     /translation="MSKYNFDRVIDRVGTDCVKWDFRTNCSTKAQKDGLPFWIADMDF
                     ECAEPIIEALRKKVEHKIFGYSSNDSDKYFNAVCDWYKRRFNWEINRKDIIFSPGVVP
                     AVAILVRILTNSNEGVIVQKPVYYPFEAKIKSNNRDVVNNPLIYENGTYRMDYDDLEE
                     KAKCSNNKVLILCSPHNPVGRVWREDELKKVVEICKKYDLWIIADEIHSDLVRKGFKH
                     TPLQSLCPEYKDKIITCIAPSKTFNLAGMQLSNIIVNNDELKKKYQEEVTAVGVATSP
                     NPFAIVATIAAYNESEDWLNELNDYLDNNIQFIDEYLKENLPKVKLVYPEGTYLAWLD
                     FTAYGLNEVELEDLMFKKANVLFDEGYIFGKEGIGFERINVACPQSLLKECMDRLKTI
                     FENL"
     misc_binding    6382..6637
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6696..7697
                     /locus_tag="JAM15_15985"
     CDS             6696..7697
                     /locus_tag="JAM15_15985"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HAT6799750.1"
                     /translation="MSTIIPKDYKSSLNVIDTQIAIKKLKDFFEMRLSNELNLIRVSS
                     PLFVLPETGANDNLNGEKAVSFDIPFMNKNAEIVQSLAKWKRLALKKYGFEVGSGLYT
                     DMNAIRKNEELDNIHSLYVDQWDWELVIDKSCRNEKTLKDVVKRLYGVFKDTEIFVCS
                     MYEGIKEILPEEITFITSQELEDMYPELSPKEREDKIVKEKKAVFITQIGKTLISGEK
                     HDGRSPDYDDWELNGDILFYNPVLDSALELSSMGIRVDEESLDRQLKLAGCEERKEFD
                     YHKMLLNGELPYTIGGGIGQSRICMYFLQKAHIGEVQVGVWPQDMIQNCSSAGIELL"
     gene            7801..8190
                     /locus_tag="JAM15_15990"
     CDS             7801..8190
                     /locus_tag="JAM15_15990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1232 domain-containing protein"
                     /protein_id="HAT6799751.1"
                     /translation="MEFLKIIINIVLDILKKILVRFKNAKFGLVFVFDLLKLPDFMTD
                     KRINIVDKIKVISVLIFTISYFVSGVDIIPEMIAGAFGFIDDAIVLIWSIGIVNEEIN
                     KYRVIIKKDKHSNIIENVEFSIKDEEE"
     gene            complement(8346..9464)
                     /locus_tag="JAM15_15995"
     CDS             complement(8346..9464)
                     /locus_tag="JAM15_15995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAT6799752.1"
                     /translation="MNIKSAFIRKRGEKFHVYVEYVEEETGKKKQKSYGSYEKKKDAE
                     KHLIEIKSTINNNKFVAPNSVTLVERCYIYLEEKKDDFSPYTLRNRRSVIRNHIEPFF
                     GDMKLIDISPNILQTYVNKIYKKYSLNSAKNSISFLTALLHEAYRLREIQEDVSSFVI
                     TPNKKDTSVTNFYTKEEAQLLLERCLDTDLAIPIYFMLGLGLRFGEAVGVRWCDVQLN
                     EGIINVKQTMVHVDGKVTFKSPKTNKSKRRLTAPTELIILLKEEKLRQNKLKLQGILK
                     NELDLICLNKKFQPWTQQKFFKPFKRLLESNNLRYIKLHELRHTNATLMLLSGTNIKT
                     ISERLGHTDIKITMNKYSHVLEEMDKEASENLSKILFK"
     gene            complement(9532..9933)
                     /locus_tag="JAM15_16000"
     CDS             complement(9532..9933)
                     /locus_tag="JAM15_16000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HAT6799753.1"
                     /translation="MKKDIYVYPAILSYDADGISVEFPDLPGCYTCADSTEEALKMAK
                     EALGLHLYGMEEDNDIIPNSTTIDKLNLEKNQIPTLIEIYMPIHRKAIENYSVKKTLT
                     IPQWLNREAEKHKVNFSQILQEALKNHLNIH"
     gene            complement(10388..12052)
                     /locus_tag="JAM15_16005"
     CDS             complement(10388..12052)
                     /locus_tag="JAM15_16005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HAT6799754.1"
                     /translation="MNNENEQLKSDLLINDEKIKNLNFKIPWYYSLWTISILILSTFS
                     TYSISFIVAIIFLFKRNKIMKKHKDSISILLSDVEKINNKYILLNDEIKMKEKHFEDL
                     CESNENKLKELSNLLDKKKVEIDKFDSENQDKFKLIEELKIEKERLDNLIKDKNILKD
                     NINTLNSHLEELKNEREELRDINTTLKNKKEELKRLSEELIQTEDEVLLQSFGLYNPK
                     YDFENSDEYMKKLKEIREMQKLLIRNKTGVKYSDSWTVDGSVQKGRTMTNQNIKTALK
                     LFNSECDIAMSKVSFKNIDSIEKRIRKAFTDTNKLNTSNKVSIKENYLNLKIDELYLY
                     YEYLQMKEEEKEEQRALREQMKEEALVQKEIENQKRKLKKEELQFKNELLRLKSTIPE
                     DEKDKLEWEQKINSIEEKLALLSKDLDDVLNREQNTRAGHVYIISNIGSFGENIYKIG
                     VTRRLDPTERINELSSASVPFKYDIHATIFSEDAPKLESALHKAFDNKRVNKVNNRKE
                     FFKVTLDEIRTEVEKNFDKTVEYTKLAEAQEYRQTLKIQELNNKLA"
     gene            complement(12693..13058)
                     /locus_tag="JAM15_16010"
     CDS             complement(12693..13058)
                     /locus_tag="JAM15_16010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6799755.1"
                     /translation="MIGYRIKELRKEKDITQKELATFLGLTPKMISFYEKEERFPPHD
                     IILKLSDFFNVSTDYLLGKVNVKNVDNLSELELIESLNFSDDIKEALKMISELSPSSQ
                     EKMFKIAKVFLEEEINEKK"
     gene            13203..13439
                     /locus_tag="JAM15_16015"
     CDS             13203..13439
                     /locus_tag="JAM15_16015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6799756.1"
                     /translation="MNKLKDFRIQKGLSRNQLGAELGLTSRYIAFLENDERVPSLNTA
                     VKIATYFNTSIEYIFLKNNCTKSTFKEKGVEKYE"
     gene            13432..14199
                     /locus_tag="JAM15_16020"
     CDS             13432..14199
                     /locus_tag="JAM15_16020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012720713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor Ant"
                     /protein_id="HAT6799757.1"
                     /translation="MNNLMIFEGKQVEVFEFNEKVLFNPYDCGKCLGISNEGVRKAIT
                     RMNKNQVIKLNNSIVTDSHIRKLHNTGENFLTESGVYKLIFKSKKEEAEKFQDWVTDE
                     VLPSIRKTGGYIHTTEDMSDDEIMARALQVAQRKIESKNRELEEKNRFINQIASSKNS
                     LLVREVAKVISKSNGIIIGEKRLYEKLRLWGLVFKNSTEPKQFAVEKGYLETVEGTRE
                     TSTGVFTYRTTRVTGKGQEYILKRLLKEEEEQLSMLS"
     gene            14254..14484
                     /locus_tag="JAM15_16025"
     CDS             14254..14484
                     /locus_tag="JAM15_16025"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799758.1"
                     /translation="MNKDIKLTKKELHCVVRHLQIYLKIENGEQVSLLPCQICNYVRV
                     CGDCNTVDKWSALKKIANMADLEINEFLEFNL"
     gene            complement(14474..14677)
                     /locus_tag="JAM15_16030"
     CDS             complement(14474..14677)
                     /locus_tag="JAM15_16030"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799759.1"
                     /translation="MTTKINSDIIEGYCPYVDDYHCITYTYKTFPLLGCKNEIRGSYS
                     FNCKFANKCNFRNDCPLKKQVKD"
     gene            14906..15235
                     /locus_tag="JAM15_16035"
     CDS             14906..15235
                     /locus_tag="JAM15_16035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAT6799760.1"
                     /translation="MSTALQFIETKDLVQELMNRDDTTDIIKMFLDREGIRRMNLVTV
                     KEFREYLKVSDSTARNMIREAMAQNHYTVIPLGSSYRIDLISFEEYVMKNAMKDRNVM
                     KKRKGVI"
     gene            15334..15552
                     /locus_tag="JAM15_16040"
     CDS             15334..15552
                     /locus_tag="JAM15_16040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799761.1"
                     /translation="MVMVFNLEKFKVGNAVRISCEKFGFEVDCIVVVATEEELNLAYF
                     DKERGCIEYQALIPEDLRYDDYILQRLG"
BASE COUNT         5686 a         1815 c         2445 g         5675 t
ORIGIN      
        1 taaagtaaag atgaattact ataggtttaa attatattat tttttattat ttttatgcct
       61 ttctcagtta ttgatgagcc ttttcttcct ttactagaaa ttaagtatcc attgcgtgtc
      121 aaatattcta gcatatttct tacttcgtat tctgtgacat tatattccat aaatttcatt
      181 aactttgtcc tccccattgg tttcatgtgc aatgatttta ggatagaaat gcatatgttt
      241 ttgtcatatt ggcttaaatc attgaatatg gacatattac ttgacatatg attattattt
      301 aattttgaag atatgttttg aggtaaatca tttattgtaa gataattgga acccatgtaa
      361 gccatgtatt caacacaatt tctcagttct ctaatattcc ccatccaagt gtatgaattt
      421 aaagcttcta aaagactctt atcgagtttt atgtttttat agggaagttc ttttaaaaat
      481 gattctaaaa gaagaggtat atcttctaat ctctttctaa gaggaggtaa atctaaagtg
      541 aacatactta tcctataaaa taaatccatc ctaaatttat tttctataat taatttttct
      601 aaatctttat ttgtggcagc taatattctc acatcaattg gaataatact tgtaccacca
      661 atttttctaa tttctttttc ttgtaagact cttaaaagtt taacctgtaa atcatgtggc
      721 atatctccta tctcatctaa aaatatagtg ccagtatgag ctaattcgaa taatcctttt
      781 tttccacctt tttttgctcc agtaaaagaa ccatcttcat atccaaatag ttcactttca
      841 agtaattcac ttggtaatga agcacaattt attgctacaa aaggtttatt ttttctgttt
      901 gaatgattgt gtattgactg agtaaaggct tctttacctg ttcctgtttc acctgttatt
      961 aatataggat tatctgtaag agccattttt tttgcctttt taatacaatc ttttataata
     1021 gaactatttc caataatatt attaaattta tatttagcta cataacctct tttgacagaa
     1081 tcacttctta ttttttgttc taatatttct atattgttta catcttttaa tgtaattaag
     1141 caaccctcta tatttttata aagataaaat ggttttttag aaagtatgaa ttttttatct
     1201 atttcgtcta tgtatataat catattatcg atgtttaagt tctttgtaat tttatctaag
     1261 aaactctttg gcatatattc cattaaggaa ggtgatttta taagtttttc atctagttcc
     1321 aacatattaa gtaaagactt atttacaaaa gtaaccttgt taaaggtgtt gaaaaatatt
     1381 agaccatcac ctatttcatc aatggtcatg taaagtatag tttttaattt agatatatta
     1441 tctaatgacg tatttaagaa atcatgactt agtgtctcct tggacaattt gtatagtttt
     1501 tctataaatt tctcattttt tagttttaat actactaata atgacatata tgtatctaat
     1561 gagatttttc tccaacctaa atcaacaata ttttttatgt attttggtat aaatctaatc
     1621 tgacctggtg ttatagctgt atctaaatca tatatttcat cacaatctgg atatgtcggt
     1681 acaaaatcta tatgatttat accaatttta tatagataag tagccatctc aaatgctgaa
     1741 gttttattgg ttgtcataag taacgatttt gtacctggag gtagtttcat cattttttca
     1801 tatccaagtt ttgaaagtgc tttcgttcca tgaataattt caatatcttc cttaaaatgt
     1861 tttattaaaa aattactagt taaaggtgat agagaaagca ctacctctcc ctctaaattt
     1921 tcttttattc catcaagtat attttgtgtt tctatgatta tttcgtctcc aaaaaagttt
     1981 gttaattctt ctttgtagtg gtcactattt aatttatcat atgttataag gattaacttc
     2041 tttttatcca ttttatttct cctaacaaaa tagtatttat ttttaaagta tttaaagtat
     2101 aaggtaagtt atattataca acaaatagta gtataaattt atatatttga ttaaataata
     2161 ggttttttta ggattttatc ctataaaaac ctattttaaa attatttttg caagataagg
     2221 aaaatagctt tttatattgt aatgtatatt ttaaatagtt aataaaaaaa tattatattt
     2281 ttaaacttga aaagtaagta attataagct atttaatcgc tggaataaat ttacaataaa
     2341 aaaataaata caaaggcttt atcattaagg tattggcata agttttgctt attaaacaag
     2401 tatactaata aaattcattt aaacaggagg gagaatttat atgagtaaat tagaatcaac
     2461 aacagaaaaa gttgaggtaa aatggtatgg gtatgtagca ttaatattgg gagcattatt
     2521 tttttcagga atatttaaag atgcaccagg accattaaaa gtattggatt ttaacaatgt
     2581 attaggttct tttggaacat tgggaacaat taatgatggt gtaggtacat tagcttcaaa
     2641 ctttagaggt gatggaggta ctggccctcg agatggatgg ctatatgcat tgacattaat
     2701 accatcagtt atgtttgcac ttggagtagt tagagttata gaccacttag atggaatgaa
     2761 ggcagctcaa aagcttctta gtccactatt aaagccatta ttagggttac ctggatttgc
     2821 aggattaact ttgatagcta gtttacagtc tacagatgca gctgcatcta tgactaaaga
     2881 acttaaagat gatgggtata tagatgaaaa acaaaaagct gtattttgtg catttcaatt
     2941 ttcaggtgcc tctgcaatta cgaatttctt tgcttctgga gcagcactat ttccatttat
     3001 aggagatgta ccaatattta taccacttgc tttaatatta attatgaagt ttgttggggc
     3061 gaacttactt agattatatt taaataaatt tgacaagggg gaagcttaac atgagtgagg
     3121 tagcaaaaaa agaggtaaaa gttaaaaaag gaaatgtgat agatgcgttt attggaggag
     3181 ctagaaatgg attccaaata agtacaaatt caatggcccc aaatgtcatc ttcggttttg
     3241 ctataatttc tgtgttcaat ttaacaggtc ttttggatgt aatagggaca atatttacac
     3301 ctgtaatgag tatatttgga cttccaggtg ttgcagcaac agctataatg acaatattta
     3361 tatcaatggg aggagcatct ggagtaatcg caggtttatt tacagcaggt caaataagtc
     3421 aagcacatgt tgcaattcta ttgccaatgt tattgctttc aggagcgcag atacaattta
     3481 tggggagact tttaggaaca gctgagttaa aaactaaata ttatccacat atgtttgtta
     3541 tagcaacttt aaatggttgt attgcaatgc ttataatgaa ttatttcgta gtataggtaa
     3601 ttataataaa aatttaatat aaatggaaag tttaaatttt aaggaggagc tagattatgg
     3661 gaactaacaa agattatatt gagtatgtac ataaagtgta tgattatcta cacactatac
     3721 cagaaaaagg atttgaagaa tataagacat cagagtttgt tttaaaagag cttgaaaaaa
     3781 tggggtttga aaatattaat aaaggagctg caggaactgg tattatagta actatagatt
     3841 ctaaaaaaga aggaccagta tttgctataa gagcagatat ggatgcattg gaatttatca
     3901 tagatggaga aaagaaaatg atacatgctt gtggtcatga tggtcatact tctatgcttt
     3961 taacagctgc aaagttaata aaagagagaa atttagtaaa aagaggtaag ttaaaaatac
     4021 tttttcaacc aggtgaagaa aaattatatg gagcattaag agtaattgat tctggtttgt
     4081 tggatgatgt agaagaaatg gtggggatgc atttaagacc tggacaagat tgtaggttgg
     4141 gaaaggcgat acctgcaatg taccattgtg ctagctgtat aatgcaattt acgattaaag
     4201 gtatcacttg tcatggttct aaaccacatt taggagtaaa tgcagtagat gctgtctgtt
     4261 tagcagtgaa tgcaataaat gcaataagag taaatccagc tataccaaat tctataaaag
     4321 taacaaatat atcagttaag ggagaaactt ataataatat accagatgaa gcatttatgg
     4381 ctttagatat aagggcagaa agtaatgata taatagaaga attaaaagaa aaagcaatac
     4441 atgctgtaaa aactgctgta agttctataa atgcagaagc tgtactaatt tccaaagatg
     4501 gagtaccagc agcagaattt gatgaagaac ttgtaaactt ggctgaagaa actataaaag
     4561 atgtattggg agctgatgca tctataggta tatttaaaaa ttctggtgga gaagatttcc
     4621 attattatac acaaaaacta aaatgtaaaa ctacatatat tggattagga gctgatgcta
     4681 caccaggatt tcataatcca aatgtaacat ttgatacgaa agctttagaa tatggtgtag
     4741 atatatggtg tagattggtt gaaaagagat tgggataata tccaaactaa taattctaca
     4801 tttaaaatta taattataga agttatagaa aaagattgct tatgttaatt agaaaataat
     4861 taatatgagc aatcttattt tgatataatg aaactgattt tggaatattg aaaaaatatg
     4921 atggaaaagt aattatattt taaatctatt ggacaaaaaa gtgatattat tataatatta
     4981 agaattgtaa aatactacta aattgcatct agtaatggac ttaacaatta taaaaatttt
     5041 attcttagga gggaaaaatg agtaagtata attttgacag agtaatagat agagtaggaa
     5101 cagattgtgt aaaatgggat tttagaacta attgttcaac aaaagcacaa aaagatggtt
     5161 tgcctttttg gattgctgat atggattttg aatgtgcaga accaataata gaagcattac
     5221 gtaaaaaagt tgaacataaa atatttggat atagttcaaa tgatagtgat aaatacttta
     5281 atgcagtttg tgattggtat aaaaggagat ttaactggga aataaataga aaagatatta
     5341 tttttagtcc tggtgttgta cctgctgttg ctattttagt aagaatatta actaattcta
     5401 atgaaggtgt aatagtccaa aaaccagtgt attacccatt tgaagctaag ataaagagca
     5461 ataataggga cgttgtaaac aatcctctaa tatatgagaa tggtacttat aggatggatt
     5521 atgatgattt agaagaaaaa gctaagtgta gcaacaataa agtactgata ctttgtagtc
     5581 ctcacaaccc tgttggaaga gtttggagag aagatgaatt aaagaaggtt gtagaaatat
     5641 gtaaaaaata tgacctatgg ataatagctg atgagataca ttctgattta gttagaaaag
     5701 gatttaaaca tactccttta cagtcattat gcccagagta caaggataaa ataattacat
     5761 gtatagctcc aagtaaaaca tttaatctgg caggaatgca gttgtctaat ataatagtga
     5821 ataatgatga actaaaaaag aaatatcaag aagaggttac agctgttgga gttgcaactt
     5881 caccaaatcc ctttgctatt gtagctacaa tagcagcata taatgaaagt gaagactggc
     5941 ttaatgaatt aaatgattac ttagataata atatacaatt tattgatgaa tacttaaaag
     6001 aaaacctacc aaaagtaaaa cttgtttatc cagaaggaac atatctagca tggttagatt
     6061 ttactgctta tggattaaat gaagtagaac ttgaggattt aatgtttaaa aaagctaatg
     6121 tattatttga tgaaggttat atatttggaa aagaaggaat aggatttgaa agaataaatg
     6181 tagcttgtcc acagtcttta ttaaaagaat gtatggacag attaaagact atatttgaaa
     6241 atttataaag tataggtaaa aatttataaa gtgtttaaaa ataaaaaaat aataaacttg
     6301 acaaatttta actaatcact tatcatacta ttatgaataa atagaaaaca taagagagct
     6361 aaattttatt gaattaaact cttaaagact ttgaaaggaa gagtagttat agaatgtaat
     6421 taaagcgagt tggtgatggt gtgagaccaa tatgaagtct ataatgaaga acatcctgga
     6481 gttgctaacc gaaattttaa aagagtaggc ttagtcggaa ccaaaccgtt atcatattgg
     6541 ggtgtatcga gtaatatctg tacattgtga gctgggtttg aatttatttc aaactaatca
     6601 gggtggtacc gcggaaaagc aacctttcgt cccttttata tagggatgaa gggttttttt
     6661 aatggaaaaa tatataaata tagggagtga atgatatgag cacaataata ccaaaggatt
     6721 ataaaagtag tttgaacgta attgatacac aaatagctat aaaaaaatta aaagattttt
     6781 ttgaaatgag actaagtaat gaattaaatc ttataagagt ttcttctccg ttatttgtat
     6841 tgccagaaac aggtgcaaat gataatttaa atggagaaaa ggctgtaagc tttgatatac
     6901 catttatgaa taaaaatgca gaaattgttc aatcacttgc aaaatggaaa agattagccc
     6961 ttaaaaaata tgggtttgaa gttggtagtg gtttatatac agatatgaat gcaataagaa
     7021 aaaatgaaga attagacaat atacattctc tttatgtaga ccaatgggat tgggaattgg
     7081 ttatagataa aagttgtaga aatgaaaaga ctctaaaaga tgttgtaaaa agattgtatg
     7141 gagtatttaa agatactgaa atttttgtat gtagtatgta tgaaggtata aaagaaatat
     7201 taccagaaga aataactttt ataacatcac aagagttaga agatatgtat ccagaattat
     7261 caccgaagga aagagaagat aaaattgtaa aagagaagaa agcagtattt ataactcaaa
     7321 taggaaaaac attaatatca ggagaaaaac atgatggaag aagccctgat tatgatgatt
     7381 gggaattgaa tggggatata ttattttaca atcctgtttt agattcagca ttagaattat
     7441 cttcaatggg aattagagtt gatgaagaat ctcttgatag acaattgaaa cttgctggat
     7501 gtgaagagag aaaagagttt gactatcata agatgctttt aaatggcgaa cttccgtata
     7561 caattggtgg aggaattggt cagtcaagaa tatgtatgta tttcttacaa aaagctcata
     7621 taggagaagt acaagttgga gtatggccac aggatatgat tcaaaattgt agtagtgcag
     7681 gaattgaatt attataattt aaatataaac taattgataa aatttatatc taatatgttc
     7741 atcaaattaa ttatatcggt tataatgtag aataacctat aattataaga ggtgataaat
     7801 atggagtttt taaaaataat cattaatata gttttagata ttttaaaaaa aattttggtc
     7861 agatttaaaa atgctaaatt tggtttggtt tttgtatttg atttacttaa actacctgat
     7921 tttatgacag ataaaagaat caatatagtt gataaaataa aggtaatttc tgtattaatt
     7981 tttactatat cctactttgt atctggggtt gatataattc cagagatgat tgcaggggca
     8041 tttggtttta tagatgatgc tatagtttta atttggagta taggtatagt gaatgaagaa
     8101 attaataagt atagagttat tataaaaaaa gataaacatt caaatataat tgaaaatgta
     8161 gaattttcta taaaagatga agaagaataa caatttatat gtgttatgct tagatattat
     8221 ataatactaa gtactactag atagtagtta aatactagct tttgctacta tctagtaata
     8281 aatatttgac tgacatttaa ctgacaaata aaaaaatatg tgattaactg acataaaact
     8341 gaccattatt taaatagtat tttgctcaaa ttttcagatg cttctttgtc catttcttca
     8401 agtacatggg agtatttatt catagttatt tttatatctg tatgccccaa tctttctgaa
     8461 atagttttta tattagttcc agaaagcaac attaaagttg catttgtatg tctaagctcg
     8521 tgcaatttta tgtatctaag attgttactc tctaataatc ttttaaaagg tttgaaaaat
     8581 ttttgttgtg tccaaggctg aaatttttta tttaagcata ttaaatctaa ttcgtttttt
     8641 agtatgcctt gtaattttaa tttgttttgt cttaactttt cttcttttaa tagtattatt
     8701 agctcagttg gtgctgttaa tcttctctta gatttgtttg ttttaggaga tttaaaagtt
     8761 acttttccat caacatgtac cattgtttgt ttcacattta taattccttc attaagttga
     8821 acatcacacc atctaactcc tacggcttca ccaaagcgta gaccaagtcc taacataaaa
     8881 tagataggta tagctaaatc agtgtcaaga catctttcta atagaagctg agcttcctct
     8941 ttagtataaa aattagttac agatgtatct tttttatttg gagttattac aaaactagaa
     9001 acatcttctt gtatttctct aagtctataa gcttcatgta ataaagcagt taaaaaacta
     9061 atagaatttt ttgcagaatt taaggaatat tttttatata tcttattaac atacgtttgt
     9121 aaaatatttg gactaatatc aattaatttc atatctccaa aaaaaggttc aatgtgattt
     9181 ctaattacac ttcttctatt tctcaaagta taaggtgaaa agtcgtcttt tttttcttca
     9241 aggtatatat aacatctttc tacaagagtc acactatttg gagcaacaaa cttattattg
     9301 tttatagtag actttatttc aattaaatgt ttttcagcat cctttttctt ttcatagctt
     9361 ccataacttt tttgtttctt tttgccagtt tcttcttcca catattccac atatacatga
     9421 aatttttccc ctctttttct tataaaagct gatttgatat tcatatatgt acgccccttt
     9481 ataagtttat atattttata taaaagagca gttaaactgc tctaattata tctaatgaat
     9541 gttaaggtga ttttttaaag cttcttgaag tatttgagag aaattaacct tatgcttctc
     9601 agcttctcga ttaagccact gagggatagt cagcgttttt ttaacagagt aattttctat
     9661 agcttttctg tgaattggca tatatatttc tatcaaagta ggtatttgat ttttctctaa
     9721 gtttaattta tctatagttg ttgaatttgg tattatgtca ttatcttctt ccatgccata
     9781 taaatgtagc cctagagctt cttttgccat ttttaatgct tcctctgttg agtctgcaca
     9841 tgtgtaacag cctggtaaat cgggaaattc tacagagata ccatctgcat cataacttag
     9901 tatagcagga tatacatata tatctttttt cattttatca accccttaca gttacattat
     9961 aaaacgtact tacatacgtg taaataagaa gaacaaacta taatagaaat ttaaatgtaa
    10021 tatataggta aaatatgtaa gaattatatg atataataat tgtagcaagg aaaataaaat
    10081 cgaaaagcta agggtgattt tctcatataa acgccaaatt ccaatatagg aaggaggtga
    10141 atttatatgt taattaactt tttattgagt atagtagctg gtattgtatc agctttcata
    10201 tatgacaaaa taaaaaatca cccaaacgcc aataagggtg atttaaagaa ataactttta
    10261 aattctaatc aattagagaa attcaccttt tacaaagtaa attttatctc cttgctatta
    10321 ttatatcaca aattggtata gatattcaaa aataatattt tattaaagta taattgtttg
    10381 aatatattta agctaattta ttatttaatt cttgtatttt taatgtttgt ctatattctt
    10441 gtgcttctgc caattttgta tattccacag tcttatcgaa atttttctca acttctgttc
    10501 ttatttcatc aagcgtaact ttgaaaaatt cttttctatt atttaccttg ttaactctct
    10561 tattatcaaa agctttatgt aaagctgatt ctaatttagg tgcatcttca ctaaatatag
    10621 tcgcatgtat atcatatttg aaaggaactg atgcactact taattcattt attctctcag
    10681 ttgggtctaa tcttctagtt actcctattt tatatatatt ttctccaaaa ctaccaatat
    10741 tagagattat gtatacatgt cctgctcttg tattttgttc tctatttaat acatcatcta
    10801 aatcttttga tagtaaagct agtttttctt ctatagaatt gattttttgt tcccattcta
    10861 atttgtcttt ttcatcttct ggtatagttg attttagtct aagtaattca ttcttgaatt
    10921 gtaattcttc tttttttagt tttcttttct gattttctat ttctttttga acaagagctt
    10981 cttctttcat ttgttctctc aaagctcttt gttcttcttt ttcctcttct ttcatttgaa
    11041 ggtattcata atataaataa agctcatcta ttttcaaatt aagatagttt tcttttatag
    11101 aaaccttatt tgaagtattt aatttatttg tatcagtaaa tgcttttcgt attctttttt
    11161 ctatagaatc aatattttta aaactaactt ttgacatagc aatgtcgcac tcactattga
    11221 agagtttaag agctgtttta atattttgat tagtcatagt tctacctttt tgaacacttc
    11281 catcaacagt ccaagaatca gaatatttta cacctgtttt atttcttatt aatagttttt
    11341 gcatttctct tatttctttt aattttttca tatattcatc agagttttca aaatcatatt
    11401 ttggattata taatccaaat gattgaagca gaacctcatc ttcagtctgt attaattctt
    11461 ctgataatct ttttagctct tcttttttat tttttaaagt tgtgtttata tctctaagct
    11521 cttccctttc attttttaat tcttctaaat gagaatttaa agtattaata ttatctttaa
    11581 gtatattttt atcttttata agattatcaa gtctttcttt ttctattttt agttcttcga
    11641 taagtttaaa tttatcttgg ttttctgaat caaatttatc aatttcaact ttctttttgt
    11701 ctaatagatt ggataattct tttaacttat tttcatttga ttcacataaa tcttcaaagt
    11761 gtttttcttt cattttaatt tcatcattta ataaaatata tttattattg attttttcga
    11821 catcagataa tagtatacta atgctatctt tatgtttttt cattatctta tttcttttaa
    11881 ataagaatat tattgcaact ataaatgata tagagtatgt tgaaaacgta gaaagaatta
    11941 gtatggatat agtccataaa gaataatacc agggtatctt gaaattaaga tttttgattt
    12001 tttcatcgtt gatgagtaaa tcacttttta actgttcatt ttcattgttc atatcaaaac
    12061 tcctttttta tttttgttct actttgtgac aataacaatt taagtatata aaactttccg
    12121 tataaatgct atgtatatta ggaaaaaaca taggattaaa tagttttgaa aagaatacta
    12181 tatttatatg gtataaaaag taaaacgaaa atttttaaat taaataataa aaaaaattat
    12241 ataaacaaga aaatacaaaa aattataatt aaaaatacga ttaataatat ataggaatgg
    12301 aaaaaactac caactctcta caaatttcga tttttttatt acaattacac tttttttatt
    12361 gcatttggaa aataaaagta ttattatgta agtaagataa ttatcaaaga caattctgaa
    12421 taatcgaaaa acgtttctag aaatgaaaaa ggtataatta catagttttt attaaaaatt
    12481 gttgggagtt tttaactaaa aataagaaca taagttcttg tgataggggg aaagtatgtg
    12541 gaaaaatcaa aaaaaatact aatcgataca ggggatgtat taaacgaaat aaaaataatt
    12601 agtgatgaga aacttgaaaa atacatagag ttgctaaaag aatattgtaa tcaagaaaat
    12661 aaaaaagaaa gagagtgatt ttctcctctt tcttattttt tctcattaat ttcttcttca
    12721 aggaaaactt ttgctatttt aaacattttt tcttgactag aagggcttaa ctcgctaatc
    12781 attttcaaag cttcttttat gtcatcagag aaatttagac tttcaattaa ttctaattcg
    12841 ctgaggttgt ctacattttt tacattcact ttaccaagta aataatctgt agatacatta
    12901 aaaaaatctg atagttttaa aattatgtca tgaggaggaa atctttcttc cttctcgtaa
    12961 aaagaaatca ttttaggagt aagccctaaa aaagttgcaa gctctttttg agtaatatct
    13021 ttttcttttc ttaattcttt tattctatat ccaatcatgt tatttagcca ccttttacaa
    13081 ttatattgaa ctattagttc ttaattatca attatagctc atttttttta aaaaagctat
    13141 tgacaatgta ctaatagtac tgtactatta gtacataaga taaaacaaaa gaaggtgaaa
    13201 aaatgaataa actaaaagat ttcagaatac aaaagggatt gagcagaaac caactaggtg
    13261 ctgaattagg tctcacaagt aggtatatag ctttcttaga gaatgacgag agagtaccat
    13321 ctttaaatac agctgtaaaa atagcaactt atttcaatac ttcaatagag tatatttttt
    13381 tgaaaaataa ctgtactaaa agtacattta aagaaaaagg agttgaaaaa tatgaataat
    13441 ttaatgatat ttgaaggtaa gcaagtagaa gtatttgagt ttaatgaaaa agttttgttt
    13501 aatccatatg attgtggaaa gtgtttagga attagtaatg aaggagttag aaaagcaatt
    13561 actagaatga ataagaatca agtgattaag ttaaataatt caattgtgac agatagtcac
    13621 attagaaaat tgcacaacac aggagaaaat tttcttactg aaagtggagt atataaacta
    13681 atattcaaat ctaaaaaaga agaagctgag aaatttcaag attgggttac tgatgaagtt
    13741 ttaccaagta taagaaaaac tggtggttat atacatacaa cagaagatat gtcagatgat
    13801 gaaataatgg caagagcatt acaagtagct caaaggaaaa tagaaagtaa aaatagagaa
    13861 ctggaagaaa aaaatagatt tattaatcaa atagcatcat caaaaaatag tttacttgta
    13921 agagaagtag ctaaggtgat ttcaaaaagt aatggaataa taattggtga gaaaaggcta
    13981 tatgaaaaat taagattatg gggtttggta tttaaaaatt caactgaacc aaagcaattt
    14041 gcagtggaaa aaggttattt agaaactgtg gaaggtacta gagagacatc aacaggtgta
    14101 tttacttata gaacaacaag agttacagga aaaggtcaag agtacattct aaaaagatta
    14161 ttaaaggaag aagaagaaca attatcaatg ttaagttaaa gcatgacagt accttgaaaa
    14221 ctaaatacag aatattcaaa aagaggtgag aggatgaata aagatataaa acttacaaaa
    14281 aaagaattgc attgtgttgt cagacatctt caaatttatt taaaaataga aaatggcgaa
    14341 caagtttctc ttttaccatg ccaaatttgt aattatgtaa gagtttgtgg agattgtaat
    14401 acagtagata aatggtctgc cttaaaaaaa atagctaata tggcagacct tgaaataaat
    14461 gaatttctag aatttaatct ttaacttgtt ttttaagagg gcagtcattt ctaaagttac
    14521 atttgttagc aaatttacaa ttaaaactgt atgagcctct tatttcattt ttacaaccta
    14581 ataaaggaaa ggttttatat gtataagtta tacagtgata atcatcaaca tatgggcagt
    14641 atccctctat tatatctgag tttattttag ttgtcataaa ttcacacctt ctttcttaat
    14701 taatttaaga cgtatccacc aatacatctt aaattaatta tagcatgatg ggttaaaagt
    14761 tagttaggag ataggaatga aaaataaaga aaaagcatta ttacttagag cagttctaat
    14821 tttaattttc tattttttag gaattgaatt tagcaaagtt ttctttaaat aataagtcta
    14881 catatacaga aagggtgaga taaaaatgag tacagcatta caattcatag aaacaaaaga
    14941 cttagttcaa gaattaatga atagagacga tacaacagac atcattaaga tgtttttaga
    15001 tagagaagga attagaagaa tgaatttagt cacagtaaag gagttccgtg agtacctaaa
    15061 agtgtctgat tcaactgcaa gaaacatgat aagagaagca atggcacaaa atcattatac
    15121 tgtaattcct ttgggtagtt catataggat agatttgatt tcttttgaag aatatgtaat
    15181 gaaaaatgca atgaaagata ggaatgtaat gaaaaaaaga aagggggtga tttaattgaa
    15241 tgtaaaggtg ctaatagctt atgtacaata ttgtaagcaa tataataaaa aagcaagttt
    15301 tgaaggtctt aaaaaataca acgaggaggt ctaattgtta tggtatttaa tttagagaaa
    15361 ttcaaagtag gcaatgcagt aagaataagt tgtgaaaaat ttggttttga agttgattgc
    15421 attgtagtag tagcaactga ggaggaacta aatctagctt actttgataa agaaagaggt
    15481 tgcatagagt atcaagcatt gataccagaa gaccttagat atgatgatta tattcttcaa
    15541 agattaggtt aggaggaaat gaaatggcag ttttaataat ggtaggttta tttgcaatat
    15601 gtttagcagg attatttcaa t
//
LOCUS       DACTZW010000096        15429 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.096, whole genome shotgun sequence.
ACCESSION   DACTZW010000096 DACTZW010000000
VERSION     DACTZW010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15429
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.096"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(<1..469)
                     /locus_tag="JAM15_16045"
     CDS             complement(<1..469)
                     /locus_tag="JAM15_16045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HAT6799762.1"
                     /translation="MAALNYAKEYSNVLAQAYPYTLNFGDLYATENNGRYRWTGSKTI
                     EIPTISTTGRVDSNRDTIAVAQRNYDNAWEPKVLTNQRKWSTLVHPADIDQTNHVASI
                     GNITQVYNEEQKFPEMDAYCISKIYADWTSLGKVADTTVITTANVLEIFDMMME"
     gene            complement(481..1044)
                     /locus_tag="JAM15_16050"
     CDS             complement(481..1044)
                     /locus_tag="JAM15_16050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="scaffolding protein"
                     /protein_id="HAT6799763.1"
                     /translation="MDWLKELLEGIKIEDNKIDIASLQKSIEKKIKETTVTQEDYVNL
                     ETQLNTANETIKKFEGGMTKEDVDNLKTTYETDKKTLEETYKKEIEEKDFNYWLGDAF
                     KSVKCRDEIALKAHLDMEALRNSKDRQKAFEEQINPLKQDKDYLFNATLEGEEPKIDT
                     ITPGQEPKITDFGFNFTGVRPHENNNK"
     gene            complement(1107..1403)
                     /locus_tag="JAM15_16055"
     CDS             complement(1107..1403)
                     /locus_tag="JAM15_16055"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799764.1"
                     /translation="MFKKDTRGYIKRHIGKPNKSSVRDIISVLIIIVGIALGFIVGLS
                     IIISNVLDVANMIDTNTFTCMKLVFNLAGMIAGYLVGRIICFVLSLTGVFIGSK"
     gene            complement(1423..1911)
                     /locus_tag="JAM15_16060"
     CDS             complement(1423..1911)
                     /locus_tag="JAM15_16060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799765.1"
                     /translation="MAKFKKKPVEVEAFKLGYDVEPKWFIENDRVCNFIQEKCIGGNV
                     SCDLETLEGTMRANKGDYIIQGVKGEIYPCKADIFEMTYQKVEYRGKNKLSTEMTLDS
                     TNFQENIKNAAKELEFFIETLEKADDKIDKLTEKMNKYACKVDVDKIVKQLVKHLREG
                     IE"
     gene            complement(1911..2306)
                     /locus_tag="JAM15_16065"
     CDS             complement(1911..2306)
                     /locus_tag="JAM15_16065"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799766.1"
                     /translation="MSKFKKKSEEVEAFKWILGSPNTPKWFYQAFEKGTIWLDESLNS
                     MNRKGEVKKTICIKYKNGVIRATNGDFIIKDSEGKIYSCTCGEFEKYYKDLDDEKTKF
                     SDKDLECLRRIPLKDAKFTFELIGIKEDE"
     gene            complement(2631..2879)
                     /locus_tag="JAM15_16070"
     CDS             complement(2631..2879)
                     /locus_tag="JAM15_16070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799767.1"
                     /translation="MDNKFKNLQHLINSIDLGLDIEFDLYSKPYNISIGDDDTRFITL
                     CPDGDTKYYKNGKDMVDNYNIDGKLLKDLWKDIQIVNM"
     gene            complement(2881..4416)
                     /locus_tag="JAM15_16075"
     CDS             complement(2881..4416)
                     /locus_tag="JAM15_16075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HAT6799768.1"
                     /translation="MKHKDYWRKRFEQLEEVQNNKSVKYYLELEKQYKLAMNSIEKDI
                     LSWYNRFAENEGISLLEAKKLLNTRELEEFKWSVEEYIKYGKENAINQKWMKELENAS
                     ARVHITRLEALKLQIQQQVEVLYGNELDSIDRLMKDIYTSGYNHTAFNIQQGVGVGWS
                     LMSLDANRINKVISKPWTSDGLNFSERIWGKHRPALVNELHTKLTQSIIRGENPKNLV
                     NDFAKRFNVSKSQAKNLIMTESAFFASASRKDCFNDLDVEKYEIVATLDLRTSNICRE
                     LDGKVFDMKDYQVGITAPPFHCRCRTTIAPWFEDEEGYRAAKGEDGKTYDVPSSMKYN
                     EWYKKYIEDRLGKEKADTLRKMQLNESKDRKQFKEYKKVLGNEIPSKFDEYQHMKYND
                     TIRYEEAKKLYKDVNWQVKNQRNLTSGSVHSVPFESKPNSVFDNYKDGKLIQRRYYGN
                     TGKPRLDLDLTDHRNPKQHKIVPHKHDWLADENNHDRVKREKDMELTKAHKIANKDIL
                     KGE"
     gene            complement(4406..5848)
                     /locus_tag="JAM15_16080"
     CDS             complement(4406..5848)
                     /locus_tag="JAM15_16080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAT6799769.1"
                     /translation="MLNIYISETDLIKAQLKKESTFNLAKVIEHYILKHRPEKYKQGE
                     EYYYGNTDINNKRRYYFLDGAKVDDFTKVNNKAINNYHKLLVDQKVGYSVGNPIVFNA
                     DDDNFTKLLNDLLGEEFDDTITELYLNASNKGIEWLHPYINRKGEFKYVIIPAEEAIP
                     IWDSKRQKELVAFIRFYYIEDIDGNKIKRVEYYTENDVTYFIERGNSFVQELLYDEYG
                     KLTEIQEGHFKVNNKEQGWGKVPFIPFKNNEKCVSDLTFYKSLIDIYDNNISTLADNL
                     DEIQEFIYVLKEYPGTSLQEFIDNIRYYKSVKVDDGGGVDKLEISIPIEAKKELLDRL
                     EKNIIIFGQGVNPESQNTGDKSGVALKFLYSLLDLKCSKTEKKFKKAIRELLWFVCEY
                     LKISSSKSYDYKSVQITFNHSMIINESEKIDMASESIGIISDETIVSNHPWVEDVNDE
                     LERLKKQEETQKEYDDLIPTNNQEGVIDET"
     gene            complement(5854..7107)
                     /locus_tag="JAM15_16085"
     CDS             complement(5854..7107)
                     /locus_tag="JAM15_16085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HAT6799770.1"
                     /translation="MVIEMIVRINFNPDFKEANFTKKRYRAMKGSAGSGKSVNVAQDY
                     ILKLGDKKYQGANLLVVRKSEATHKYSTYAELTGAINRIYGKQADKYWKTTLNPLEIK
                     SKVTGNSIIFRGVNDAKQREKLKSINFSKGKLTWVWCEEATELMESDIDILDDRLRGI
                     LTNPNLYYQMTFTFNPVSATHWIKRKYFDYKNDDIFTHHSTYLQNRFIDEAYYRRMQM
                     RKEQDPEGYKVYGLGEWGETGGAILKNYVIHEFPTEFEYFDNMRLSQDFGFNHANAIL
                     RIGFKDGELYICNEIYVHEMDTSEIIKIANSRGLEKTLFMYCDSAEPDRIKMWKSAGY
                     KAKGVKKGPGSVKAQIDYLKQLRIHVHPSCINTIKEMQQWKWKQDERTGLYLDEPIEF
                     MDDAMAALRYSIDNKLKNNGISFLK"
     gene            complement(7085..7774)
                     /locus_tag="JAM15_16090"
     CDS             complement(7085..7774)
                     /locus_tag="JAM15_16090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017697483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799771.1"
                     /translation="MNEKADLAHEDYLKGLKYKEIAEKHNVSLSTVKSWATRYWKQKG
                     CNQPKKVATKKRGAPIGNKNATGPPGNKNAEKFGFFSKYLPEETRELIQEISIKDKFD
                     ILWEQITIQYAAIIRAQKIMYVKDKEEMIKELKKHESTENGEKIEYEFQFAWDRQASF
                     LNAQSRAMSELRSLIKQYDEMIHKDWNLATEEQKTRVEKLKCEVANLNKDDIGDDELK
                     ISVDYGDRNDS"
     gene            complement(7831..9864)
                     /locus_tag="JAM15_16095"
     CDS             complement(7831..9864)
                     /locus_tag="JAM15_16095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012102269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799772.1"
                     /translation="METELCVQAIVTASKVVKATGADEMIKNLVEKFLSNKVGEVLGK
                     QRSKKELKLIENKFNEYMERSYKNYIYMNTIVFRNQQKTIDDLYIPLTVSKRNVFDSS
                     YEEDEICISINSYKDDFLPKYKKVLLIDQAGMGKSTIAKYLYLSSINESKGIPILIEL
                     RRLSQEKDIIDFIMNEINGISEHFDKEGVLKLIERGDFIFFFDGYDEINKEYKTQVTE
                     KLQNFVDKAGNNTFLMTSREEDELLSFGNFQSFYIYPLKKEEAYNLIKKYNDDNEEVS
                     KLLIKKIEEDKNFEIIKEFLENPLMVSLLCESFKYKQSIPHKKDAFYRQVYDALFEKH
                     DYSKRAGYYREKKSGLNLEEFHKILRTIGFITLTKGVSYSKEELINIIYNSKRKNIGL
                     EFNENDLLYDLIHNVPVFVKDGIEYRWSHKSFQEYFAASYICYDSDEKSMLLKKMSEG
                     NRINKYYNVLDFCYDIDYKSFMRSIILPTIKDLDKFFYEKYHNDVYNDFDKGELSLRK
                     AILFNYEKVYIYILSENKINYFKNKKGARLERNAYIRDKFPIEKNSNASGIIFNGIFS
                     VMGLRKENITNLLKLLKRKESNLVCHVRYDSLSNDELIYNISHGLYVFEDNIDNELNK
                     KEYFKFANDILYKYLKSLFVEAGTVIFNYEECINIKREIEKEIEEEQNDIDFL"
     gene            complement(9983..10549)
                     /locus_tag="JAM15_16100"
     CDS             complement(9983..10549)
                     /locus_tag="JAM15_16100"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799773.1"
                     /translation="MLNQFNEFLGNYINIISVIASFASIAALIISIIAFMESNKQAKL
                     ILKYRRNNEDNMAGDYYENGNGYIRLDLNKIDDKSNVYAEIRSNNLVDFVIENKSKIV
                     AKSPILSLKFINMEVDIEENNNFEQINSELRWHPKDNTTIHKGINFRIEQFNFKNCVM
                     LKKEAYIEVVLSADNMETKEFSIPIKAY"
     gene            complement(10982..11659)
                     /locus_tag="JAM15_16105"
     CDS             complement(10982..11659)
                     /locus_tag="JAM15_16105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRO family protein"
                     /protein_id="HAT6799774.1"
                     /translation="MLKILQEKNVKMIWSKDGEEVWFHAGDVGEELGIVNIHDTLRNI
                     DREYKKKFKDSDVGVSYNRNFKVKLNNRGEVFVTEEAVYNMSFRSNKAEAKLFTKWVT
                     KTLKQIRIHGYYIATEKDQEWLDIRTEGKKVRKDFTDEIQEFVYYATGQGSNKPQMYY
                     KHFTELVRKKLGIPKGVKRDELNQSELFDIQALERIISMKLPKLIDKDMNYKEVYKKI
                     KELIEMI"
     gene            complement(12002..13144)
                     /locus_tag="JAM15_16110"
     CDS             complement(12002..13144)
                     /locus_tag="JAM15_16110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAT6799775.1"
                     /translation="MNDFNGERLKKARIYREMTVVELAQKMKCERQVISMYENNKLKP
                     SDNIIKRIAKELYFPSKFFLEKEKKIIQGSSYFRALLTTNKKYRKKQVERMEFLSQIY
                     FFLQDYIEFPTLNLPNCFYKTPEEAALLLREAWGLGLKPINNLIYEVEKHGIIVTGFP
                     TSIDYIDTFSQMIDIEGKTMYLIGYSNNNTSASRLHFDIAHELGHICLHEWSEDVEAL
                     EKQEFKDRESEANRFASAFLLPEETFKIDAKRTPLRIPNYTELKRKWKVSIQAMIRRS
                     YSLGIISMDEYQSMIRTLQRRGLRKSEPLDDELLTSLPALLKTAVLMLLNEKIFTSKE
                     FMNELSFSYNFSLDPKELENILDLPNNTLNSSKILYLSDVNRLGRA"
     gene            complement(13310..13816)
                     /locus_tag="JAM15_16115"
     CDS             complement(13310..13816)
                     /locus_tag="JAM15_16115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799776.1"
                     /translation="MSKTKKEFFNATKKQLSNYKQLNANIIKLKNEIQMLKDNSVGDL
                     TKAISYDSVKTGKTNKTSNMIEDAIVNVSDLITEKEIELYESEIIKSTIDLAIRNLKP
                     IHKQIITYKYIEGLEWSLIVDKVYLEERQLRERANQAINSISIALFGKKALIEQEPLF
                     ELLDYRLN"
     gene            complement(14207..14572)
                     /locus_tag="JAM15_16120"
     CDS             complement(14207..14572)
                     /locus_tag="JAM15_16120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HAT6799777.1"
                     /translation="MKINFTIDGEPIGKERPRFNLSTKRTYTPNKTRDYEDLIKCLYQ
                     SKVKHHFDGYIKMTLRCYYSIAKSNSKKVKEQKRNNVLRPSKKPDIDNVIKAVADSLN
                     EIAYKDDTQIVEVVLEDIV"
     gene            complement(14562..14957)
                     /locus_tag="JAM15_16125"
     CDS             complement(14562..14957)
                     /locus_tag="JAM15_16125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799778.1"
                     /translation="MKDVWLYSWDDEYFASDEYESKEEAIEAAKEELKRFGEFGRLVY
                     VGKKEEVNIPNIDAEKALERVQDRIDDEFGGYGEDWFENIHVEDILILENRISEVFKK
                     WIDEFGYKPYWFVVRDTEEIELNEVANEN"
     gene            complement(15100..>15429)
                     /locus_tag="JAM15_16130"
     CDS             complement(15100..>15429)
                     /locus_tag="JAM15_16130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor-like protein"
                     /protein_id="HAT6799779.1"
                     /translation="ENYNCKNYFEDMCMLERIEINNLKVCESYIEGKNELYELEKGYT
                     MHPKDLKILFAKGEDYSVEVTHIQSGITVKCCSENSFLKNKNKCLEILEEELIKINSC
                     LELKDLR"
BASE COUNT         4714 a         2781 c         1506 g         6428 t
ORIGIN      
        1 tttccatcat catatcaaat atttctaaga catttgcagt tgtaataact gttgtatctg
       61 ctactttgcc tagtgatgtc caatcagcat atattttaga tatacaataa gcgtccattt
      121 cagggaactt ttgttcttca ttgtatactt gagttatatt acctattgaa gctacatgat
      181 tagtttggtc aatatccgct ggatgaacta atgttgacca ttttctttgg ttagttaata
      241 ccttgggttc ccaagcatta tcatagtttc tttgagctac tgctattgta tctctgtttg
      301 aatctaccct tccagttgta gatatagttg gtatttctat tgttttagac ccagtccatc
      361 tatatcttcc attattttct gtagcataca aatccccgaa gtttaaagta taaggatatg
      421 cttgtgctaa aacatttgaa tattcttttg cataatttag tgctgccatt ttatttcctc
      481 ctatttatta ttattttcat gaggtcttac cccagtaaaa ttaaaaccaa aatcagttat
      541 tttaggttct tgacctggtg ttatcgtatc tattttaggt tcttcacctt ctagtgttgc
      601 attaaacaaa taatctttat cctgtttcaa agggtttatt tgctcttcaa aagccttttg
      661 tctatcttta ctatttctta gtgcttccat gtctaaatga gcttttaatg ctatttcatc
      721 cctacattta acagacttaa aagcatcacc taaccagtaa ttaaagtctt tttcttcaat
      781 ttcttttttg taagtttctt ctaaagtttt cttatcagtt tcataagttg tttttaagtt
      841 atctacatct tcttttgtca tacctccttc aaacttttta atagtttcat tagccgtatt
      901 aagttgtgtt tcaagattta cataatcttc ttgagtaact gtagtctctt ttattttctt
      961 ttctatagac ttttgaagag aagctatatc aatcttgtta tcctctattt ttattccttc
     1021 cagtagttct tttaaccaat ccatttttaa tatctccttt catttttttc aaaataaaaa
     1081 agcctcttaa aagactttta aataatttat ttactaccaa taaaaacacc tgttaatgat
     1141 aatacaaaac agattattct tcctactaaa taacctgcta tcatgcctgc taaattaaaa
     1201 acaagcttca tacaagtaaa cgtgttagta tctatcatat tagctacatc taatacattt
     1261 gatataatta tacttaaacc tacaataaaa cccaaagcta tcccaacaat tataataaga
     1321 actgatataa tatctctaac acttgattta tttggctttc caatgtgtct ttttatatat
     1381 cctcttgtat cttttttaaa catatttcca tcccctcaaa acttattcaa tgccttctct
     1441 taggtgtttc actaactgtt ttacaatctt atctacatca actttacaag catatttatt
     1501 cattttttct gttagtttat caattttatc atctgctttt tctaaggttt ctataaaaaa
     1561 ctctaattcc tttgcggcat ttttaatatt ttcttgaaag tttgttgaat ctaaagtcat
     1621 ctctgttgat aatttatttt ttcctctata ttctactttt tgatatgtca tttcaaatat
     1681 atctgcttta catggatata tttctccttt tacaccttgt ataatataat cccctttatt
     1741 agctctcata gtaccttcta atgtttctaa gtcacaactc acattaccac caatacattt
     1801 ttcttgtata aaattacaga ctctatcatt ctcaataaac cattttggtt ctacatcata
     1861 acctagttta aaagcttcta cttcaactgg tttcttctta aatttagcca ttattcatcc
     1921 tccttaattc ctataagttc aaatgtaaat tttgcgtcct ttaatggtat tcttcttaaa
     1981 cattctaaat ctttatcaga aaactttgtt ttttcatcat ctaaatcctt ataatacttt
     2041 tcaaattccc cacatgtaca agaatagatt ttaccttcac tatcttttat aataaaatct
     2101 ccattagttg ctctaataac tccattttta tactttatac agatagtttt ctttacttca
     2161 cctttacgat tcatagagtt taaagattca tcaagccata tagttccttt ctcaaaggct
     2221 tgataaaacc atttaggagt attagggctt cctaatatcc atttaaatgc ttctacttcc
     2281 tcagatttct ttttaaattt agacatttta cttattcccc cttaaatttt taatcatatc
     2341 ttcattgcta actagtaaag aacatatgat aaatatcaca cctaaaataa aattaagtag
     2401 tggaaataaa gctagaaaaa taaaattata tttttttctt tttctgatat tcatactttt
     2461 aagtaattca attaattcct tattactatc aatcttcatt ttgaataaat aaacccctgt
     2521 gaaaaacaca attattgata aaatatataa tttaagcatt tcaaatcacc ctctcaacta
     2581 aatttttaca taataaaagc acctactaat taatcattta gcaagtgctt ttacatattt
     2641 actatctgta tatctttcca taaatccttt agtaatttgc catcaatgtt gtaattatca
     2701 accatatcct taccattttt ataatacttt gtatctccat caggacaaag agtaataaat
     2761 cttgtatcat catctccgat agatatatta tatggtttgc tatataagtc aaattctata
     2821 tctaatccta aatcaataga attaattaaa tgttgcaaat tcttaaattt attatccatt
     2881 ttattctcct ttcaaaatat ctttgttagc tattttatga gcctttgtaa gctccatatc
     2941 cttctctctt tttaccctat catggttatt ttcatcagct aaccaatcat gtttatgagg
     3001 tacaattttg tgttgctttg ggtttctatg gtcagttaaa tctaaatcta atctaggttt
     3061 tcctgtatta ccatagtatc ttctttgaat taatttacca tctttgtaat tatcaaatac
     3121 actatttggt tttgattcaa atggcactga atgaacactt ccactagtta aatttctctg
     3181 attcttaact tgccaattta catctttata aagcttttta gcttcctcat accttatagt
     3241 atcattatac ttcatatgtt ggtattcatc aaatttagaa ggtatttcat ttcctaatac
     3301 ttttttatat tccttaaatt gttttctatc tttactctca tttagttgca tttttctaag
     3361 agtatcagct ttttcttttc caagtctatc ttcaatatat ttcttatacc actcattata
     3421 cttcatacta gatggtacat catatgtttt tccatcttct ccttttgctg ctctgtaacc
     3481 ttcttcgtcc tcaaaccaag gagctattgt tgtccgacaa cgacaatgaa atggtggagc
     3541 tgttatccca acttgataat ctttcatatc aaatacttta ccatctaatt ctctacatat
     3601 atttgaggtt cttaaatcta atgtggcaac tatctcatat ttttctacat ctaaatcgtt
     3661 gaaacaatct ttcctagaag ctgatgcaaa gaaagctgat tcagtcatta ttaaattctt
     3721 agcttgagat ttagatacat taaatctctt agcaaagtca tttactagat tctttggatt
     3781 ttcacctcta ataatacttt gagttaattt agtgtgtagt tcatttacta aagcaggtct
     3841 atgtttaccc caaattcttt ctgagaaatt taacccatca ctggtccatg gcttagaaat
     3901 aactttattt attctgttag catcaagact cattaaactc catccaacac caacaccttg
     3961 ttgaatgtta aaagctgtat gattatatcc acttgtataa atatctttca ttaacctatc
     4021 aatgctatca agttcatttc cataaagcac ttccacttgt tgttgtattt gcagttttaa
     4081 agcttcaagc ctcgttatat gaacccttgc actagcattt tctaactctt tcatccactt
     4141 ttgattaata gcattttctt tgccatattt aatatattcc tcaacactcc acttaaactc
     4201 ttccaactct cttgtgttaa gtagtttctt agcttctaac aaagaaatac cttcattttc
     4261 agcaaatctg ttataccatg ataatatatc tttttctata ctattcatag ctaatttgta
     4321 ttgcttttct aattcaagat aatattttac acttttattg ttttgaactt cttctaattg
     4381 ttcaaatctc ttcctccaat aatctttatg tttcatctat aacaccctct tgattattag
     4441 taggaattaa atcatcatat tctttttggg tttcttcctg ttttttaagt ctttcaagtt
     4501 cgtcattaac atcttcaacc caaggatgat tactaacaat agtttcatct gatataattc
     4561 caattgattc agaagccata tctatttttt cagactcatt tattatcata gaatgattaa
     4621 atgttatttg aactgactta taatcatagc tcttactact acttatcttt aaatactcac
     4681 atacaaacca taaaagctct ctaattgctt ttttaaactt cttttcagtc ttagaacatt
     4741 ttaaatcaag tagtgaatat aaaaatttaa gtgctacacc cgatttatca cctgtgtttt
     4801 gagactcagg attaactcct tgaccaaaaa taattatatt tttttctaat ctgtcaagaa
     4861 gttccttttt agcttcaata ggtatactta tttctaattt atcaactcca cctccatcat
     4921 ctactttaac cgatttatag tatcttatat tatctataaa ctcctgtaga cttgtgcctg
     4981 gatactcttt taatacataa ataaactctt gtatctcatc taaattatct gctagtgtag
     5041 aaatattatt gtcatatata tctattaatg atttatagaa agttaaatct gagacacact
     5101 tttcattatt tttgaaaggt ataaatggaa ctttacccca tccttgctct ttattattta
     5161 ctttgaaatg tccttcttgt atctctgtta attttccata ttcatcatat aaaagctctt
     5221 gaacaaaact attacctctt tcaataaagt aagttacgtc attttctgta taatattcaa
     5281 ctctttttat cttgttacca tctatatctt caatgtagta aaacctaata aatgcaacta
     5341 attctttttg cctcttacta tcccaaatag gaatagcttc ctcagcaggt attattacat
     5401 atttaaactc accttttcta ttaatatatg gatgtaacca ttcaatccct ttattactag
     5461 cattaaggta tagttctgtt attgtatcgt caaattcttc ccctagcagg tcatttaaaa
     5521 gcttagtgaa attgtcatca tctgcattaa atactattgg atttccaaca ctatagccca
     5581 ccttttggtc aactaaaagt ttatggtagt tattaattgc cttattatta actttagtaa
     5641 aatcatcaac cttagctcca tctaagaaat aatatcttct cttattgttt atatcagtat
     5701 taccataata gtattcttct ccttgcttat acttctctgg tctatgcttt aaaatataat
     5761 gctctataac ttttgctaga ttaaaagtac tctctttttt tagttgagct tttattaaat
     5821 ctgtttcact tatataaata ttcaacacct cctttacttc aagaagctta ttccattatt
     5881 tttaagttta ttatctatag aatatctaag agcagccatt gcatcatcca taaattcaat
     5941 tggttcatca agatataatc cagttctttc atcttgtttc catttccatt gttgcatttc
     6001 ttttattgta tttatacaac taggatgtac atgtattctt aattgtttca aataatctat
     6061 ttgagcttta acacttcctg gtcctttttt aactccttta gctttatatc ctgcactttt
     6121 ccacatctta attctatctg gttcagcact atcacagtac ataaatagag tcttttctaa
     6181 acctctacta tttgcaattt ttatgatttc tgaggtatcc atttcatgta catatatttc
     6241 attacatata tataactctc catccttaaa accaattcta agtattgcat ttgcatgatt
     6301 aaagccaaag tcttgtgaca gtctcatatt gtcaaagtat tcaaattctg tgggaaattc
     6361 atgtataaca taatttttaa gtattgctcc accagtttct ccccattctc caagaccata
     6421 tactttgtac ccttctgggt cttgctcttt tctcatttgc attcttctgt agtaagcttc
     6481 atctatgaat ctattttgta gataagtact atgatgagta aatatatcat catttttata
     6541 gtcaaaatac tttcttttta tccaatgagt ggctgaaacc ggattaaatg taaatgtcat
     6601 ttgataatac aagttaggat tagttaaaat acctcttaaa cggtcatcta gtatatctat
     6661 atcactttcc ataagttctg tagcttcttc acaccaaacc catgttaatt ttcctttcga
     6721 gaagttaatt gattttaatt tttctctttg ttttgcatca ttaactcctc tgaaaattat
     6781 agagttacca gtaactttac tcttaatttc taaaggattt aaagtagttt tccaatactt
     6841 atcagcttgt ttaccataaa tacgatttat agctcctgta agctctgcat acgttgaata
     6901 cttatgtgta gcttctgact ttctaactac taatagatta gctccttgat acttcttatc
     6961 tcctaacttt aatatatagt cttgtgctac attaacagat tttccactcc ctgctgaacc
     7021 tttcattgct ctgtatcttt ttttagtaaa attagcttcc ttgaaatctg gattaaaatt
     7081 tattctaact atcatttcta tcaccataat ctacacttat tttcaactca tcatctccaa
     7141 tatcatcttt atttaggtta gcaacctcac atttcaactt ctcaactctt gttttctgct
     7201 cctctgtagc taaattccaa tccttatgaa tcatttcatc atactgcttt ataagactcc
     7261 ttaactcact cattgcccta ctctgtgcat taagaaaaga tgcttgccta tcccatgcaa
     7321 attgaaattc atattctatc ttctcgccat tttctgtact ttcatgtttc ttaagttcct
     7381 taatcatttc ttccttatct ttaacataca ttatcttctg tgctcttatt attgctgcat
     7441 attgaattgt tatctgttcc caaagaatat caaatttatc ttttatagat atttcttgta
     7501 tcaattccct agtttcttcg ggtagatatt ttgaaaagaa accaaacttt tcagcatttt
     7561 tattacctgg tggaccagta gcgtttttat tacctatggg tgcacctctc tttttggttg
     7621 caactttttt tggttggttg caaccttttt gtttccagta tctagttgcc catgatttta
     7681 cagtcgataa acttacatta tgtttttcag ctatttcctt gtacttaagc ccttttaagt
     7741 aatcttcatg ggctaaatct gccttttcat tcatatcacc acctcgtttt tgtcgttttg
     7801 ggaataaaaa aagaactctt gttagagttc ttataggaag tctatgtcat tttgttcttc
     7861 ttctatttct ttctctatct ctcttttaat attaatacat tcttcataat taaaaattac
     7921 agttccagct tctacaaata aagattttaa atatttatat agaatatcat tggcgaattt
     7981 aaaatattct tttttattta attcattatc aatattatct tcaaaaacat aaagaccatg
     8041 gctaatattg tatattaatt cgtcattaga aagagaatca taccttacat gacaaacaag
     8101 gttagactct tttcttttta ataatttcaa taaatttgtt atattttctt ttctaagccc
     8161 cattactgaa aatattccat taaaaattat accactagca ttactatttt tctctatagg
     8221 aaatttatct ctaatatagg cattcctttc aagtcttgcc ccttttttat tcttaaaata
     8281 atttatttta ttttcactca atatataaat atatactttt tcataattga acaatatagc
     8341 ttttcttagt gataattcac ctttatcaaa atcattgtat acatcattat gatatttttc
     8401 atagaagaat ttatctaaat cttttattgt tggaagtatt atacttcgca taaaactctt
     8461 atagtctata tcatagcaaa aatccaaaac attataatat ttatttattc tgtttccctc
     8521 agacattttc tttagtaaca tagatttttc atctgagtca taacaaatat aactagctgc
     8581 aaaatactct tgaaaagact tatgagacca tctatattca ataccatctt taacaaaaac
     8641 aggaacatta tgaattaaat cataaagtaa atcattttca ttaaattcaa gacctatatt
     8701 ttttcttttt gaattataga ttatattaat aagctcttct ttagaataac taacaccttt
     8761 agttaatgtt ataaatccaa tagttcttaa tattttatgg aattcttcta gatttaaacc
     8821 actcttcttt tctctataat atccagctct ttttgagtaa tcatgttttt caaatagtgc
     8881 atcataaact tgtctataaa aagcatcttt tttatgagga attgattgtt tgtatttgaa
     8941 agattcacat aataaagaaa ccattaaagg attttctaaa aactctttaa ttatttcaaa
     9001 atttttatct tcttcaatct tcttaattaa taattttgaa acttcttcat tatcatcatt
     9061 atacttttta attaaattat atgcctcttc tttttttagt ggatatatat aaaaactttg
     9121 aaaattacca aaagatagaa gttcatcctc ttctcttgat gtcattaaaa aagtattatt
     9181 tccagctttg tcaacaaaat tttggagttt ttcagtaact tgcgttttat attctttatt
     9241 tatttcatca taaccatcaa agaaaaatat aaaatcacct ctttcaatta attttaaaac
     9301 tccttcttta tcgaagtgtt cacttattcc attaatttca ttcattataa aatctattat
     9361 atctttttct tgcgataatc ttcttaattc tattaatata ggtattcctt tagattcatt
     9421 tattgagctt aaatataaat atttagctat agttgatttt cccatacctg cttggtctat
     9481 taataaaacc tttttgtact ttggtaaaaa atcatcctta taactattaa ttgaaataca
     9541 aatttcatcc tcttcataag aagaatcaaa aacattacgt tttgatactg ttaatggtat
     9601 atataaatca tcaattgttt tttgttgatt tctaaatact atagtattca tgtaaatata
     9661 atttttataa cttctttcca tatattcgtt aaatttattt tctattaatt ttaattcttt
     9721 tttactcctt tgttttccaa gtacttctcc tactttatta cttaaaaatt tttcaactaa
     9781 attttttatc atttcatcgg caccagttgc ctttacaact ttgcttgctg taacaattgc
     9841 ttgtacacat aattctgttt ccatatatat cccctccaaa gtataaaatt caacttcaaa
     9901 ggtcaatatc cttcaaaaac tattcgacaa ctacaaaata ataaaatttt cactaaaaaa
     9961 agaactcttg ttattgagtt ctttaatacg cttttattgg tatactaaat tcttttgttt
    10021 ccatattatc agctgataat actacttcta tataagcttc ttttttaagc ataacacaat
    10081 ttttaaaatt aaattgctct attctaaaat ttattccttt atgaattgta gtattatctt
    10141 ttggatgcca tctaagttca ctatttattt gttcaaagtt attattttct tcaatatcta
    10201 cttccatgtt aataaatttc aaacttaata taggactttt tgcaacaatc ttacttttgt
    10261 tttctattac aaaatcaact aaattattac tacgaatttc agcataaaca ttagatttat
    10321 catctatctt atttaaatca agcctaatat atccattgcc attttcataa taatcaccag
    10381 ccatattatc ctcattattt cttctatatt ttaatatcaa tttagcttgt ttattagatt
    10441 ccataaaagc tataattgat ataatcaagg ctgctattga tgcaaatgat gcaattacag
    10501 aaattatatt tatatagtta ccaagaaatt cattaaactg attgagcata tctttttctc
    10561 cttaaaaaca ttaccttatt ttattatatt tgtataatat tttttacatt tacttttaat
    10621 ttattacaca aacttcttac ataaaaaaag accatctata aagatgattc tctagactaa
    10681 gtatctatgt ttttgtttat actctgtaac agcatcattt catgcttctt gctctcttat
    10741 tcctttttct ctagcaatcc tttgtgctat ctttctaact aattcagcac tttttaatat
    10801 tcctatacta accacttcct tatctctatt ttatattata ccacataata aagaataaag
    10861 ctaattccta ctaagttcta ttactctgtt tcataagttc aaaaccttaa tcccataaca
    10921 catttaccat tctcctttta atttatttta taaaaataga ccatccatca agatagtcac
    10981 tttaaatcat ttctattaat tctttaatct ttttatatac ttctttataa ttcatatctt
    11041 tgtctatcaa cttaggtaac ttcatagata taattctttc aagtgcttgt atatcaaaca
    11101 gttcactttg atttaactca tctcttttca caccttttgg tatacctaat ttctttctca
    11161 caagttcagt aaaatgttta taatacatct gaggtttatt acttccttga ccagtagcat
    11221 aataaacaaa ctcttgtatt tcatctgtaa aatcttttct aaccttttta ccttctgttc
    11281 ttatatctag ccattcttgg tctttttctg tagcaatata ataaccatgt attctaattt
    11341 gtttaagcgt ttttgtaacc cattttgtaa ataattttgc ttctgcttta ttacttctaa
    11401 atgacatatt atacacagct tcttctgtaa caaatacttc tccacgatta ttcaacttaa
    11461 ctttaaaatt tcggttatag gaaactccga catctgaatc cttaaatttc tttttatatt
    11521 ccctatctat atttcttaat gtatcatgaa tatttactat gcctaattcc tctcctacat
    11581 ctccagcatg aaaccaaact tcttctccat cttttgacca tatcatcttt acatttttct
    11641 cttgtaaaat tttcaacata ctactacctc ctaaattagt tattaataaa gaatattcaa
    11701 tttgaatacc tttattttcg ccccctcaat atgagggaca taaaaaaatc gcattaaaaa
    11761 agacctagaa gttaatctaa gtctttttag tgggggatac atattattta agggagcaag
    11821 ttctaggaat cgaacctaga ttaaaccact acttgcatgg tgagtgaggt taccaagccc
    11881 cactcgattt tagactctga attaagatac aaaattgtat gagattttag tcttaattca
    11941 aatacttaat atagtgtatc aatagatttt gaacatagtt agaattgaac taacaacatc
    12001 ctcatgccct gcctagtctg ttcacatctg ataaatacaa aattttacta gaatttaatg
    12061 tattgtttgg taaatctaat atattttcta gctcttttgg atctaaacta aagttatagg
    12121 agaatgaaag ttcattcata aattcttttg aagtaaatat tttttcattc aataacatca
    12181 aaactgctgt ttttaacaat gctggtagag aagttaataa ttcatcatct aatggttctg
    12241 attttcttag tcccctacgt tgtaaagtac gaatcataga ctggtattca tccatactga
    12301 taattcctaa agaatatgaa cgacgaatca ttgcttgtat agaaactttc catttacgtt
    12361 tcaattctgt atagtttggg atacgtaaag gagttctctt agcatcaatt ttaaaagtct
    12421 cttctggtaa taagaatgca gatgcaaatc tattagcttc tgattctctg tctttaaatt
    12481 cttgtttttc taaagcttct acatcctcgc tccactcatg taagcatata tgacctaatt
    12541 catgagctat atcaaaatgt agtctagaag cagaagtgtt attgtttgaa tacccaatca
    12601 aatacatagt ttttccttca atatctatca tctgactaaa tgtatctata taatctattg
    12661 aagtaggaaa tcctgtaaca attattccat gtttttctac ctcataaatt aaattattaa
    12721 taggttttaa tcccaacccc caagcttctc ttaaaagtag agcggcttct tcgggtgtct
    12781 tataaaagca gtttggtaaa tttaatgttg gaaactcaat ataatcttgc aagaagaaat
    12841 atatttgaga taaaaattcc attctttcaa cttgcttttt tctatatttt ttatttgtag
    12901 tcaacaatgc tctaaaataa gatgaaccct gtataatttt cttttctttt tctaaaaaaa
    12961 atttagatgg aaaatacaat tctttcgcta tccttttgat tatattatcg ctaggtttta
    13021 atttattatt ttcatacata gaaatgactt gtctttcaca tttcattttt tgagctaatt
    13081 caactactgt catttctctg tatatacgag ctttctttag acgttctcca ttaaaatcat
    13141 tcatatttaa tactccattc aaaatcttta tatgttggct agagtgcaga taatcccaac
    13201 tctagccaac tatttaattt tgagagggaa atctttcatt tccacaatac tattatctca
    13261 tgtctaaaat taaaaaaacg gcacattttc ggcaattaaa attcatagtc taatttagtc
    13321 tgtaatctaa caattcaaaa agtggttcct gctctattaa tgctttcttt ccaaataatg
    13381 ctattgatat tgaatttata gcttgattag ctctttctct caattgtctt tcttctaaat
    13441 ataccttatc aactattaaa ctccattcta agccttcaat atatttgtat gttatgattt
    13501 gtttgtgtat aggttttaaa ttccttatag ctaaatctat ggtagattta attatttctg
    13561 actcatataa ctctatttct ttttctgtta ttaagtctga tacattaaca atagcatcct
    13621 caatcatatt actagttttg tttgtttttc ctgttttgac actatcataa cttatagctt
    13681 ttgttaaatc tccaactgaa ttatctttca acatttgtat ttcatttttt aattttatta
    13741 tatttgcatt taattgtttg taattagaaa gttgtttctt agttgcatta aaaaactctt
    13801 ttttagtttt agacatactc acacactcct atcaattatt tatgttataa taatatttgt
    13861 atataaaagt tttatatttt tgacaagtgg agtgtgaaag cactcctttt ttcttttgaa
    13921 taattcattt caatttattt acaattctaa aaaatctatt gttattatta atatctcata
    13981 gtatcctaac cttatatcat ctaaccttag gaggatttta tgagagatat aatagttttc
    14041 ttaataagac tttgtattta ttttttactg gcatttgctg cacaaaaact caataagaca
    14101 tatccattca aaaagcatat ctttatatgg atttgtttaa ttttattgat atcgtttttt
    14161 atagaataca ttaataagtt tattgtgact tttgtttaga ttctttttat acaatatcct
    14221 ctagtacaac ctcaactatc tgtgtatcat ctttataagc tatctcattg agtgaatcag
    14281 ctaccgcttt gataacattg tcaatatcag gtttcttact gggtcttaac acattatttc
    14341 ttttctgctc tttaaccttt ttactgttac ttttagctat agaataatag caccttaaag
    14401 tcatttttat gtatccatca aagtgatgtt tgactttaga ttgatataga cattttatta
    14461 ggtcctcata atctctagtc ttattagggg tataggttct tttagtagac aaattaaatc
    14521 taggtctttc ttttccgatt ggttctccat ctattgtaaa attaattttc atttgcgacc
    14581 tcatttagtt ctatttcttc cgtatctcta acaacaaacc aatatggttt atatccaaat
    14641 tcatctatcc attttttaaa tacttcactt atcctattct ctagtatcaa tatatcttca
    14701 acatgtatat tttcaaacca atcttcacca tatcctccaa attcatcatc aattctatct
    14761 tgaacacgct ctaacgcttt ttctgcatct atgttaggta tattaacctc ttctttttta
    14821 ccaacataaa ccaatctacc gaactcccca aaccttttaa gttcttcctt agctgcttca
    14881 atagcttcct ctttactttc gtattcatca cttgcaaaat attcatcatc ccagctatat
    14941 agccacacat ctttcatata aattcctcct ctatttattt ttcttcttag ctttctttct
    15001 acaatcctta caacaataaa tatccttaga tttttcctta atataaaata attttccaca
    15061 ccaactgcat cttcttcgtt tcatagaatc acttcctatt tagcgtaaat cttttagctc
    15121 taagcaagag tttattttta tcaattcttc ttccaaaatt tccagacact tgtttttatt
    15181 ttttaaaaag ctattttcgg aacaacattt tactgtgata ccactttgaa tatgagtaac
    15241 ttcaacagaa taatcttcac ctttcgcaaa aagtattttc aaatctttag gatgcatagt
    15301 atatcctttt tctaattcat atagctcatt tttaccttca atgtaacttt cacacacttt
    15361 caagttatta atttcaattc tttcaagcat acacatatct tcaaagtaat ttttacaatt
    15421 ataattttc
//
LOCUS       DACTZW010000097        14942 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.097, whole genome shotgun sequence.
ACCESSION   DACTZW010000097 DACTZW010000000
VERSION     DACTZW010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14942)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14942)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14942
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.097"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            26..1531
                     /gene="ade"
                     /locus_tag="JAM15_16135"
     CDS             26..1531
                     /gene="ade"
                     /locus_tag="JAM15_16135"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HAT6799780.1"
                     /translation="MSPGFIDAHMHIESTMVMPIELSKKLLKSGTTTIIADPHELVNV
                     KGASAIDFLLESTKDIPLNVYIMVPSSVPATSFETNGVGKFSAKDMESYVNNPRILGL
                     GEVMCFNDVINSENEILDKLELFKNKVVDGHAPNINGKSLQTYVCAGIENDHECITFD
                     EVYEKLRAGLKILIREGSAAKNLKSIVSGMLKHNLPIEEFMFCTDDKHLDDIEKQGHI
                     RWNIKCAIDLGMEPVRAIKVATYNSAKAYGLRKIGAIGAGYKADIVVLNDLDKMEVDS
                     VYKDGNLVNEEMFSNYNYEIKDKELLNTVKFKYINKEKIQLKVSEKNYVMEIVPYQIL
                     TNKVYESLPCADGYFVPNKEYSKLCVVERHRMTGNVAIAPLKGFGIKNGAIATTVAHD
                     SHNIIVAGDNDDDILVAINYLKEIQGGYVIVSNGKVLAYLSLQVAGLISTFTAEEVQE
                     ITDNMLEIARKMGVPEYVDPFITLSFMALPVVPQIRLTDLGLFDVEEFKFI"
     gene            1883..2347
                     /gene="bcp"
                     /locus_tag="JAM15_16140"
     CDS             1883..2347
                     /gene="bcp"
                     /locus_tag="JAM15_16140"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent thiol peroxidase"
                     /protein_id="HAT6799781.1"
                     /translation="MLSIGTKAPEFTLEDKDGNKVSMSDFKGKKVIVYFYPKDNTPGC
                     TRQACAFRNAYDGFKKEDIQVIGISKDSIKSHQKFAEKHELPFILLSDPDLVAIKAFD
                     VWKEKKMYGKTALGVVRATYIIDENGIIEKVFEKAKPDTNAQEILEYLEKQE"
     gene            2357..3100
                     /gene="yaaA"
                     /locus_tag="JAM15_16145"
     CDS             2357..3100
                     /gene="yaaA"
                     /locus_tag="JAM15_16145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HAT6799782.1"
                     /translation="MIIMLSPAKNMKNIEVFDRDLSLPCFIDNTKEIVENIKTFGIED
                     FKNKMKINEKLAVLNKNRFESIKFDRLGNPAILTYDGIQYKNIEAENFTRKDEEFANS
                     CIRIISGLYGVVKPYDSIYEYRLEMQTKLRVGEFKNLYEYWENRIYKELIKEKTAIVN
                     LSSNEYSKSIEKFIKDSDTYITCTFKVNKNGILKVESTQAKKARGMMAKYIVKNRIRD
                     IEELKKFNLEGYKYKENLSNNSEYIFVKE"
     gene            3228..5918
                     /locus_tag="JAM15_16150"
     CDS             3228..5918
                     /locus_tag="JAM15_16150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006771590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAT6799783.1"
                     /translation="MENHKQMPWHSRATHEILESLDSSEEGLTDTEAEKRLKENGLNE
                     LRKKPPRTTLQMLWSQITDAMVMILIGAAILSLIFGEFTEAFVILIIVTVNAVIGIVQ
                     EKKAESSLEALKNMNSPTARVMRDGEENVIPASNLVVGDIVFLEDGAMVPADLRLIET
                     SSLKIQEASLTGESVPSEKDADTILPKECVLGDRSNMAYTSSIVTYGRGVGVVVATGM
                     DTEVGNIAHLLDSQDDFDTPIKRKLNTVGKTLSVIGIIVCVVIFAIGAFYQRPLLPMF
                     MIAISLAISIIPEGLPATATIVMALGVQRMAKRNALIRKLPAVETLGGATVICCDKTG
                     TLTLNKMTVTHIAVNGDFESGKVTSIDTASEKHPLVYKEIVYAGALCNDACINPDKTD
                     EILGDPTEGALIFMAKKFGIDQEALEEEYPRVFEQPFDSDRKCMTTVHNIDEKIIAYT
                     KGAVDEILDLCTKILTSKGERNITEVDKKNIHELCLNMSKDALRVLGFAKREISSIPK
                     EDSENIEYDLTFIGMVGMIDPPRTEVIDAVSTCKEAGIRTIMITGDHKVTATTIAHEL
                     GIWSEENTVISGDELDNLSDYELDEAVKNTTVFARVSPFDKLRIIQSLKRIGEVPAMT
                     GDGVNDSPALKSADIGIAMGISGTDVAKDSSDMILMDDSFTTIAYAIKEGRRVYRNIQ
                     KVIQFLLVGNIAEILTLFVAILLNWDTPLLAVHILWVNLATATLPALALGVDPPSRNI
                     MKHQPVKSTTLFEKNLIQRVVTQGIFVAIMTILAYKIGLNIENHSVGQTMAFCVLAFS
                     QMLRAFSQRSNTDSMFNRNNGKNPFLLISFLTSAFLIAVILFVPVFRNAFNLTVLNNL
                     EWLITIVLAIMSVIQVEVGKIIKRKKEKNKKIVDKIRKNI"
     regulatory      5946..6048
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            6158..7423
                     /locus_tag="JAM15_16155"
     CDS             6158..7423
                     /locus_tag="JAM15_16155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HAT6799784.1"
                     /translation="MYNKETICVQGNYKPGNGEPRVLPLYQSTTFKYSSIDQLAELFD
                     LKVDGHIYSRISNPTIQAFEEKISLLEGGVSSVAVSSGQSANMLAVLNICKSGDSILC
                     SSKVYGGTFNLLGPSLKKFGIDLISFDLDSSEDEIVELAKENTKVVFAETLANPTLEV
                     IDFEKIANVAKRINVPFIVDNSLASPVLCNPLKYGANIVTHSTTKYLDGHASSVGGII
                     VDGGNFNWDNGKFPELVEPDPTYHGISYTQKFGNAAYATKARVQLLRDYGNCLSPFNA
                     YLTNLNVETLHLRMERHSENALKIARFLEKHENVDWINYPGLEDNKYYENAKKYLSRG
                     CSGVLSFGVRGGLENAKKFVEKLQIASLVTHVSDVRTCVIHPASTTHRQLTEEQLIAS
                     GVLPSLIRLSVGIENVEDLIADLNQALNF"
     gene            7453..8343
                     /gene="metA"
                     /locus_tag="JAM15_16160"
     CDS             7453..8343
                     /gene="metA"
                     /locus_tag="JAM15_16160"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HAT6799785.1"
                     /translation="MALILPKGLPVINKLLDEGIDVIYKEDFKKELKYEENIDTKIAI
                     LNLMPIKIDTELDLLRRIDKTGFNVSVEFIKISTRESKRSCNEYVKEFYKTFDEAKGE
                     YFDGFIITGAPVEQMEFEEVDYWNELEEIMDYSKRKTKSTLYICWAAQASLYKYYNVK
                     KLPLRQKCFGVFKHKVDKDSKIVDGFENEFFAPHSRHTTVNIEALKESKELSIVSHSK
                     EAGPYIITNSRDVFVMGHSEYDKYTLDKEYKRDINKGDKISIPQNYYINDDPSEEPTV
                     KWKKHSELLFRNWIKNYLIQ"
     gene            8834..9277
                     /locus_tag="JAM15_16165"
     CDS             8834..9277
                     /locus_tag="JAM15_16165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAT6799786.1"
                     /translation="MDEMSFKKELLELTRDINMKFTTLLSDFYQPLGITAVQALILSE
                     LCEHGEKKISDLGKNLNMTNSNVSVICQRLEKNGFLNRIRDIEDQRIVKVKVTNKSLD
                     IQEHISSSIFDSYFENMTSEKLQDMEDIIEGLEKLNKLLTYIDCK"
     gene            9308..11125
                     /gene="hflB"
                     /locus_tag="JAM15_16170"
     CDS             9308..11125
                     /gene="hflB"
                     /locus_tag="JAM15_16170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HAT6799787.1"
                     /translation="MDEHKPQKRSALYYYTVIIIVVMFLNALIFPSLMDKKMVEIDYG
                     KFLTMLDTGKVKSVEIENNRIAINPSSSKDKNIYITGRMDDPELVDRLKNAKVEFTKV
                     IPKENSPLLSILLTWIIPIGILMLFGNLMMKSMQKRMGGNAMQFGKSNAKMYVSAQSG
                     KRFNDVAGQDEAKEALTEIVDFLHNPEKYKKIGAQMPKGALLVGPPGTGKTLLAKAVA
                     GEANVPFFSISGSEFVEMFVGMGASRIRDLFKQAKEKAPCIVFIDEIDTIGKKRDNGS
                     GLGGNDEREQTLNQLLSEMDGFDGGIGVVILAATNRPDSLDKALLRPGRFDRRIPVEL
                     PDLGGREAILKVHAQNVNVSSDIDYNAIARSTSGASGAELANIVNEAALLAVKSGRDI
                     VEQQDFDESVETVIAGYQRKGAVISDKEKKIIAYHEIGHALVAAMQKHSAPVHKITII
                     PRTSGALGYTMQVAEDESVLMSKEEAIDKITTFTGGRAAEEVIFNTCTSGASNDIEQA
                     TKIARAMVTRLGMSEEFDMVALETVSNQYLGGDTSLACSSDTAAKIDEEVFKIVKACH
                     KNAIEILENNIDKLHELANYLLEKETITGDEFMEILNLN"
     gene            11303..14005
                     /locus_tag="JAM15_16175"
     CDS             11303..14005
                     /locus_tag="JAM15_16175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase KdpD"
                     /protein_id="HAT6799788.1"
                     /translation="MDRPNPDILLEKIKNEEEKLSRGQLKIFFGYAAGVGKTYSMLES
                     AQNLKKVGVDVVVGYIEPHTRPETLALLDGLEILPVKEIEYKSIKLKEFDLDAALARK
                     PEVILVDEFAHSNVAGLRHTKRWQDIEELLLAGINVYTTVNVQHLESLNDIVEVITNV
                     SVKETIPDKFLDTNTQLELIDVEPDVLLERFNEGKIYKKEQATRAKNNFFIKDNLVAL
                     REIALRKTAERVNKEVQMTRLSKGDVTVIPTSDTLLACISPSPSSAKVIRTASRISDS
                     TFAKWIALYVETPNTARLPFDEQKQLQNNLKLAKKLGGEIIVLHGENIIEQILRIAKL
                     RNVTKIVIGRNHSSNKRFSKRFKKDIVDKLIDEVDYIDIHIIPYKFASDVKYRPKKDK
                     SSIKSKFKISKVDFIKLIFITLMISILAYAVQSMGFIRENILLIYMLGVVLVSMWTKG
                     YSTGIISSVFNIVLLNYFFTAPLYTLSIADSNYIVTLVVFSIVGIITSTLTSKIQHEA
                     ETAAKREENTKMIYQIIKGFLRLSNKDDIVNKGIELLSLSLSRDVICYLNVDKHNKSK
                     LYKKNTNNKDKNDLDSEDEKAVASWVLSNSTVAGNDTDTLPGSKGYYIPIVGMNLTLG
                     VVGISCIDSKLDTEDISLIETIIAQMAIALDREILSEAKENTNLEIERERLRSNLLRA
                     VSHDLRTPLAGISGAVSTIIKNKGTIGQDIIDELLSGVYEDTQWLIRLVENLLSMTKI
                     DEGKLEVKKHSELVEEIISEALQKIKKRIENALIDINIPEQILFVPMDAKLIEQVLIN
                     LIDNSLKYSKEDCKIEINVYEKDDYVWFEVSDNGPGISKELKKHIFDRFFTGEEGAKD
                     SRKGVGLGLSICKSIIQAHKGEIMVENNKDKGSTFKFSLPKENE"
     gene            14039..14737
                     /locus_tag="JAM15_16180"
     CDS             14039..14737
                     /locus_tag="JAM15_16180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6799789.1"
                     /translation="MSKKLILLVEDDKTIRKFISTALLTQDYDVKEAITGKEGISIAV
                     SYSPDVVLLDLGLEDMDGIEVIKAIRQFSNIPIIVVSAREQDRDKVEVFDAGADDYLT
                     KPFSIVELLARVRVAFRHSQVEAQQKDDVKSMFEVDKLLIDFDKRKVIVDDVEVHLTP
                     IEYNILSLLAKHHGKVLTHNFIIKEIWGSVIGNETKSLRVFMATLRRKIEKQPANPRY
                     IITEVGVGYRLNDE"
BASE COUNT         5855 a         1706 c         2734 g         4647 t
ORIGIN      
        1 ggaggttcag tgtagcaaca aatatatatc acctggtttt attgatgcac atatgcatat
       61 tgaatctaca atggtaatgc caattgaatt atcgaaaaaa ttattaaaat caggtacgac
      121 aactatcata gccgacccac atgagttggt caatgtaaaa ggagctagtg caatagattt
      181 tttattagaa tcgacaaagg atataccact taatgtatat attatggtgc cttcatccgt
      241 acctgcaaca agttttgaaa ctaatggagt tggtaaattt agtgcaaaag acatggagag
      301 ttatgtaaat aatcctagaa ttttaggttt aggagaggta atgtgtttta atgatgttat
      361 aaattctgaa aatgaaatct tggataaact agagcttttt aaaaataaag ttgtagatgg
      421 acatgcacct aatataaatg gtaaatcact tcagacatat gtatgtgcag gaatagaaaa
      481 tgaccatgaa tgtataactt ttgatgaagt atatgaaaaa ttgagagcag gattaaaaat
      541 tttaataaga gaaggaagcg cagcaaaaaa tttaaagtct atagtaagtg gtatgctaaa
      601 gcataacttg ccaattgaag aatttatgtt ttgcacagat gataagcact tagatgatat
      661 agaaaaacaa ggtcacataa gatggaatat aaaatgtgcg attgatttag gtatggaacc
      721 tgttagggct ataaaagttg caacttataa ttctgcaaaa gcatatgggt taaggaaaat
      781 tggagcaata ggtgcgggtt ataaggcaga tattgttgta ttgaatgatt tagacaaaat
      841 ggaagtggat agtgtatata aagatggtaa tttggtaaac gaagagatgt tttctaatta
      901 caattatgag attaaagata aagaattgct taatacagtc aagtttaagt atattaataa
      961 agaaaaaata cagttaaaag taagtgaaaa aaattatgta atggagattg taccttatca
     1021 aattttgaca aataaggtat atgaatcttt accatgtgca gatggatatt ttgttccaaa
     1081 taaagagtat tcaaaacttt gtgttgttga gagacataga atgactggaa atgtagcaat
     1141 tgctccacta aaaggatttg gcataaaaaa tggagcaatt gctactactg tggctcatga
     1201 ttctcataat attatagttg caggggataa tgatgatgat attctagtag ccataaatta
     1261 cttaaaggaa atacaaggtg gttatgtaat tgtatcaaat ggaaaagttc ttgcatacct
     1321 aagtcttcaa gtagctggat taattagtac ttttacagct gaagaagtac aagaaattac
     1381 tgataatatg ttggagatag caagaaaaat gggagttcca gagtatgtag acccttttat
     1441 tacactttct tttatggcac ttccagttgt tccacaaata agacttacag atttaggtct
     1501 atttgatgtt gaggaattta aatttatata gataatataa aagtaataat aaatgaggct
     1561 ttctcaaaat agggataagt ctctttttat tgttggaatg atgaaaatat atttgatttc
     1621 atacaaaaaa gagcgtctca tgaactaaaa attttatttt tagatatcct tattttaatt
     1681 aatctatcat ttaaccttat tttaagcata gatatcttaa taaaactatt ttcagtctat
     1741 tttaacatat aaatacatga aaattatata tttatgaaac tttatacata aaaaataaaa
     1801 tattttattt atatatagat ttatagggta ataatataag catagtataa aattattaat
     1861 aaaaacaaaa ggagagatat ttatgttgag tataggaaca aaagcaccag aatttacact
     1921 agaagataaa gatggaaata aggtaagtat gtcagatttt aaaggcaaaa aagtaatagt
     1981 atatttttat cctaaagata atacaccagg atgtacacgt caagcttgtg cttttagaaa
     2041 tgcatatgat ggatttaaaa aggaagatat acaagttatt gggataagta aagatagtat
     2101 aaaatcacat caaaaatttg cagaaaagca tgaacttcct tttattttac tttctgaccc
     2161 tgacttagtt gctataaaag cttttgatgt atggaaagag aaaaaaatgt atggaaaaac
     2221 tgcattggga gttgtacgtg cgacatatat tatagatgaa aatggaatta ttgaaaaagt
     2281 ctttgaaaaa gcaaaaccag acacaaatgc acaagagatt cttgaatatt tggaaaaaca
     2341 ggagtgataa gaatttatga ttataatgtt atcaccagct aaaaatatga agaatataga
     2401 agtatttgat agagatttga gtttgccttg ttttatagat aacacaaaag aaatagtgga
     2461 aaatataaag acatttggta tagaagattt taaaaataaa atgaaaatta atgaaaaatt
     2521 agctgtatta aataaaaata gatttgaaag cattaaattt gatagattag gaaaccctgc
     2581 aatcttaact tatgatggaa tacaatataa aaatatagaa gcagaaaatt ttacaaggaa
     2641 agatgaagag tttgcaaata gctgtattcg aatcataagt ggattgtatg gtgttgtaaa
     2701 accatatgat agtatatatg aatatagatt agaaatgcag acaaaattac gagtaggtga
     2761 gtttaagaat ttatacgaat attgggaaaa tcgtatatat aaagaactaa tcaaagaaaa
     2821 aacagctatc gttaatcttt catcaaatga atacagcaaa tccatagaaa aatttattaa
     2881 agatagtgat acatatatta catgtacttt taaagtaaat aaaaatggca tattgaaagt
     2941 ggaatctaca caagcaaaga aagctagagg tatgatggca aaatacattg taaaaaatag
     3001 gataagagat attgaagaac tgaaaaagtt taatttagaa ggttataagt ataaagaaaa
     3061 cttatctaac aatagtgaat acatatttgt aaaagagtag aagttttgtt aaatattaaa
     3121 tggcattgtt aaatttaggt aaaatatact tagtgtgtat tgaattgaac ttgattttaa
     3181 aatataatta ttcttaaatt aaaaaaagaa aggagtggtc ttccaaaatg gaaaatcaca
     3241 aacagatgcc ttggcattca agagcaacgc atgaaatttt agaaagtcta gattcatcag
     3301 aggaggggct caccgatacc gaggcggaaa aacggcttaa agagaatggc ttaaatgaac
     3361 ttagaaaaaa accacctaga acaactttac aaatgctttg gagtcaaatt acagatgcta
     3421 tggttatgat actaatagga gcagcaatat tatctttgat atttggcgaa tttacagaag
     3481 cttttgtaat actaataatt gtaacagtaa atgcagttat tggaattgtt caagagaaaa
     3541 aagcagaatc atcattagaa gcattaaaaa atatgaactc acctacagct cgtgttatgc
     3601 gtgatggtga agaaaatgtt attccagcaa gtaatcttgt agtaggagat attgtttttt
     3661 tagaagatgg agctatggtt ccagcagacc ttcgtttaat agaaacatca agtttaaaaa
     3721 ttcaagaggc ttctttaaca ggagaatctg ttccatcaga aaaagatgca gatacaatct
     3781 tacctaaaga atgtgtatta ggagaccgta gcaatatggc gtatacatct tcaatagtca
     3841 catatggtag aggtgtaggt gttgtagtag caactggtat ggatacagaa gtgggtaaca
     3901 tagcacatct tttagattca caagatgatt ttgatactcc tataaaacgt aaacttaata
     3961 ctgttggaaa gacattaagt gtcataggta ttattgtatg cgttgttata tttgcaatag
     4021 gtgcatttta tcagagacct ctcttgccaa tgtttatgat tgcaatttcc cttgccatat
     4081 caattattcc agagggatta cctgcaacag ctactattgt aatggcttta ggcgtacagc
     4141 gtatggctaa aagaaatgct ttaattagaa aattacctgc tgttgaaaca ttaggaggag
     4201 ctacagtaat atgttgtgat aaaactggta cattaacctt aaataaaatg actgttacac
     4261 atattgctgt caatggagat tttgaatctg gaaaagtgac atcaatagat actgcatctg
     4321 aaaaacatcc attagtgtat aaagagattg tttatgctgg tgcactttgt aatgatgcat
     4381 gtattaatcc agataaaaca gatgaaatat taggtgaccc aacagagggc gcattaattt
     4441 ttatggccaa aaaatttgga atagatcaag aagctcttga agaagaatat ccacgtgtat
     4501 ttgaacagcc ttttgattca gatagaaaat gtatgacaac tgttcataat atagatgaaa
     4561 agattattgc ttatactaaa ggagcagtag acgaaattct cgacctatgt actaaaatat
     4621 taacttcaaa aggtgaaaga aacattaccg aagtggataa aaagaatata cacgaattat
     4681 gtcttaacat gtctaaagat gcattgcgtg tacttggttt tgctaagcgt gagatttcat
     4741 ctataccaaa agaagatagt gaaaatatag aatatgattt gacatttata ggtatggttg
     4801 gtatgattga cccaccaaga actgaggtaa ttgatgcagt aagtacttgt aaagaagcag
     4861 gtataagaac cataatgata acaggtgacc ataaagttac tgccacaaca atcgctcatg
     4921 agttaggaat atggagtgaa gaaaatactg tgatatctgg tgatgaactt gataatttga
     4981 gtgattatga actagatgaa gctgttaaaa atactacagt atttgctcgt gtgtccccat
     5041 ttgataaact tagaattata caatctctaa aaagaattgg agaagtacca gcaatgactg
     5101 gggatggtgt aaatgactct cctgccttaa agtctgctga tattggtata gccatgggta
     5161 taagtggtac agatgttgca aaagattctt ctgacatgat tttaatggac gatagtttta
     5221 caacaattgc ttatgcaata aaagaaggta gacgtgtata tagaaacata caaaaagtta
     5281 tacaattttt gcttgttggt aatatagcag agatacttac gttgtttgta gcaatattat
     5341 taaattggga tactccgctt cttgctgtcc atattctatg ggtaaacctt gcaactgcta
     5401 cgcttccagc ccttgctctt ggagttgacc caccaagcag aaatataatg aagcaccagc
     5461 cagtgaaatc aaccactttg tttgaaaaaa atcttataca aagagttgtt acccaaggta
     5521 tatttgtggc aataatgact attttagcat ataaaattgg tcttaatata gaaaatcatt
     5581 ctgtaggtca aacaatggca ttttgtgtat tagcattttc acagatgtta cgagcattta
     5641 gtcagcgttc aaatacagat tcaatgttta atagaaataa tggtaaaaat ccatttcttt
     5701 taatctcatt tttaacttct gcatttttaa tagcagtaat actgtttgta cctgttttta
     5761 gaaatgcttt taacttaaca gttttaaata acttagagtg gcttataacg attgttttag
     5821 ccataatgtc tgtaattcaa gtagaggttg ggaaaattat taaaagaaaa aaagaaaaaa
     5881 ataaaaaaat agttgacaaa attaggaaaa atatataaga tataaaacat agaaaaatta
     5941 aataaatctt atccagagag gtggagggac tggccctatg aaacccggca accagtatat
     6001 ttatatacat tggtgctaaa tcctgcggcg aaagctgaga gatgagtata attaagctta
     6061 tacagagcct gagttatata ctcaggcttt atttatttta actctcatct gataaatagt
     6121 ttaatttttt ttactaaaat ctaaggggga tacaagaatg tataataaag aaacaatatg
     6181 tgtgcaagga aattataaac caggtaatgg agaaccaaga gtattacctt tatatcaaag
     6241 tacaactttt aaatatagca gtatagacca acttgctgaa ttatttgatt taaaagttga
     6301 tggacatata tattcaagaa taagcaatcc tactattcaa gcttttgaag aaaaaataag
     6361 tttactagag ggtggagtat cttctgtagc tgtatcatca gggcaatctg caaatatgtt
     6421 ggcagtttta aatatatgta aatcaggaga tagtatactt tgttcttcaa aagtatatgg
     6481 aggaacattc aatttactag gacctagtct taaaaaattt ggtatagatt taatatcgtt
     6541 tgacttagat tcaagtgaag atgagatagt agaacttgca aaggaaaata ctaaggttgt
     6601 atttgcagaa acacttgcaa atccgactct tgaagtcata gattttgaaa aaatagcaaa
     6661 tgtagctaag agaattaatg ttccatttat tgttgataat tcattagcat ctccagtgct
     6721 ttgtaaccct ttaaagtatg gagcaaatat agttactcat tctaccacaa aatatttaga
     6781 tgggcatgct tcaagtgttg gaggaattat agtggatggt ggaaacttta actgggataa
     6841 tggaaaattt ccagaattag ttgagccaga cccaacatat catggaataa gctatactca
     6901 aaaatttgga aatgccgcat atgcaactaa agcaagagtt cagttgctta gagactatgg
     6961 aaattgttta agcccattca atgcgtatct tactaattta aatgttgaaa cactacatct
     7021 tagaatggag agacatagtg aaaatgcact taaaatagct agatttttag aaaaacatga
     7081 aaatgtagat tggattaatt acccaggact tgaagataac aagtattatg agaatgccaa
     7141 aaagtattta tcaagaggat gtagtggtgt tttatcattt ggagtaagag gtgggttaga
     7201 aaatgccaaa aaatttgtgg aaaaattaca gatagcatct ttggttacac atgtttcaga
     7261 tgtaagaact tgtgttatac atccagcttc aactactcat agacaattaa cagaagaaca
     7321 attaattgca tctggagtat tgccttcact aataagatta tctgttggaa tagaaaatgt
     7381 agaggattta atagctgatt taaatcaagc tttaaatttc taatattcta agagaaagag
     7441 aagtgaaaag atatggcttt aatactacca aagggattac ctgttattaa taaattatta
     7501 gatgaaggaa tagatgtaat ttataaagaa gattttaaaa aggaattaaa gtatgaagaa
     7561 aacatagaca ctaaaatagc tatactaaat ctaatgccta taaagataga tacagaatta
     7621 gatttactaa gaaggataga taaaacagga ttcaacgtgt ctgtggaatt tattaaaatt
     7681 tcaacaagag aaagtaaaag aagttgtaat gaatatgtta aagaatttta taaaacattt
     7741 gatgaagcca aaggagagta ttttgatggc tttataataa caggagctcc agttgaacaa
     7801 atggagtttg aagaagttga ttattggaat gaactagaag aaattatgga ttattctaag
     7861 agaaaaacta aatctacatt atatatatgt tgggcagctc aagcaagtct ttacaaatac
     7921 tacaatgtaa aaaaacttcc actaaggcaa aaatgttttg gagtatttaa gcataaggta
     7981 gataaagata gtaaaatagt agatggattt gaaaatgaat tttttgctcc acattcaaga
     8041 catactactg taaatattga agctttgaaa gagagtaaag agttgagcat tgtgagtcat
     8101 tctaaagaag ctggtcccta tataattaca aattcaagag atgtgttcgt aatgggtcat
     8161 agcgagtatg acaaatacac tcttgataaa gaatataaga gggatataaa taaaggagat
     8221 aaaatatcta tacctcaaaa ttactatatt aatgatgacc cttcagaaga gccaactgta
     8281 aaatggaaaa aacattcaga attgttgttt agaaattgga taaaaaacta tttgatacaa
     8341 taaattttaa gagtatataa atgttaacta aaaaaacata gaaatttata ggtataaagt
     8401 taatcttaat gatactttat accttatttt tttaaaattt gaccttataa tagtagtttt
     8461 atattttaag aaaatcactt taggtgtatg tagatagagg tggttttaat tttatatatg
     8521 gtgagataat gggagactaa acctttatag tatcaataaa tttgtatttt aacttttaaa
     8581 agagattaaa aagggagaaa tcagtgtaaa atatatatat cgatttttta ttaaatttta
     8641 ttaaaaatat cctgtataaa attaaatatc aataagataa caaaattcca attgaagtta
     8701 caatattgta attgacaata aatacttaat actataatat ttaatacatt aaacattata
     8761 gtattaagta tttatttaca gtatgcactt cagcctaaat ttgaaataaa gtattttcgt
     8821 agggagcgtt tgtatggatg agatgagttt taagaaagag ctactagagt tgactagaga
     8881 tataaatatg aaatttacaa ctttattaag tgatttttat cagccacttg gtattacagc
     8941 agtgcaagct ttgattttat ctgagttatg tgaacatgga gagaaaaaaa taagcgattt
     9001 agggaagaac ttaaacatga caaatagtaa tgtatcagta atctgtcaaa ggcttgaaaa
     9061 aaatggcttt ttaaatcgca taagagatat agaagaccaa cgaattgtaa aagtaaaagt
     9121 tacaaataaa tcattggata tacaagaaca tatttcaagt agtatttttg atagttattt
     9181 tgaaaatatg accagtgaaa aattgcaaga tatggaagat ataatagaag gtttagagaa
     9241 attaaataaa cttttaactt acattgattg caaataacat aaaaataatt taaaggagaa
     9301 taaaattatg gatgaacata aaccccaaaa aaggtcagca ctctattatt atacagttat
     9361 aataatagta gtaatgtttt taaatgcttt aatatttcca agtttaatgg ataaaaaaat
     9421 ggttgagatt gactatggaa agtttctcac aatgttggat acaggaaagg ttaaatctgt
     9481 tgagatagaa aataatagaa tagcaataaa tccatctagt agcaaggata agaatatata
     9541 cataactggt agaatggatg acccagaatt ggtagataga ctaaaaaatg caaaagtaga
     9601 atttactaag gttattccta aggaaaattc acctctttta agtattttac ttacatggat
     9661 aatacctata ggtattctta tgctatttgg taacttaatg atgaagtcta tgcaaaagcg
     9721 aatgggtggt aatgctatgc aatttggaaa aagcaacgcc aaaatgtatg tatctgctca
     9781 aagtggaaaa agatttaatg atgtagctgg tcaagatgag gcaaaagaag ctttaactga
     9841 aatagtagat ttcttacaca atccagaaaa gtataaaaag ataggagcac aaatgcctaa
     9901 aggagcactt ttagtaggac ctccaggtac aggaaaaaca ctccttgcaa aagctgtagc
     9961 aggtgaagca aatgtaccat ttttctcaat atctggttct gagtttgttg agatgtttgt
    10021 aggaatggga gcttctagga ttcgtgattt atttaaacaa gcaaaagaaa aagctccatg
    10081 tatagtgttt atagatgaga ttgatactat tggtaaaaag cgtgataatg gaagtggact
    10141 aggtggaaat gatgaacgtg aacaaacttt aaatcagttg ctgagtgaga tggatggttt
    10201 tgatggtgga attggagtag taatacttgc tgctacaaat agacctgaca gtcttgacaa
    10261 agcattactt cgtccaggaa gatttgatag acgtatacca gttgaacttc cagaccttgg
    10321 aggacgtgaa gctatattaa aggtacatgc tcaaaatgta aatgtaagct cagatataga
    10381 ttataatgca attgcaaggt ctacatcagg agcatcaggt gcagaacttg caaatattgt
    10441 aaacgaagca gcacttttag cagttaagtc tggcagagat atagtagaac aacaggattt
    10501 tgatgaatct gttgaaactg taattgctgg gtatcaacgt aaaggagctg taatttcaga
    10561 caaggaaaag aaaattatag catatcatga aataggtcat gcacttgttg ctgctatgca
    10621 aaaacattct gcacctgtcc ataagattac tataatacct agaacttcag gagcattggg
    10681 atatactatg caagttgctg aagatgagag tgtacttatg tctaaagaag aagcaattga
    10741 taaaataact acttttacag gtggtcgtgc tgctgaagag gttatcttta acacttgtac
    10801 atcaggagca tcaaatgata tagaacaagc tactaaaatt gcaagagcta tggttactcg
    10861 ccttggtatg agtgaagagt ttgatatggt cgctcttgaa actgtaagca atcaatattt
    10921 aggaggagat acttctcttg cttgttcttc cgacactgct gctaaaatag atgaagaggt
    10981 atttaaaata gtaaaggctt gtcacaaaaa tgcaattgaa atcttagaaa ataatattga
    11041 taaattgcat gaacttgcta attatttatt agaaaaagaa actattacag gtgatgagtt
    11101 tatggaaata cttaacttaa actaaaatga ttatacacaa gataaaaatg cctattgtta
    11161 ggcattttta ttttacaact aaattgttta aattcatatt taaatcttta cataatctta
    11221 atcattaaaa atacatctta actacaattt tatatcggaa ttgatattat aatagtaatg
    11281 aatggtgtaa ggaggttttt taatggatag acctaatcct gatattctat tagaaaaaat
    11341 taaaaatgaa gaagaaaaac taagtagagg tcaattaaaa atattctttg gttatgcagc
    11401 tggagtagga aaaacctact ctatgttgga atctgcacaa aatttaaaaa aagtgggtgt
    11461 agatgtagta gttggatata ttgaaccaca cactagacca gaaacattgg ctttacttga
    11521 tggcttggaa attcttcctg taaaggagat agaatataaa tctataaaac taaaagaatt
    11581 tgatttagat gctgctttag caagaaaacc agaagttata ttagtagatg aatttgccca
    11641 ttctaatgtt gctgggttaa ggcatacaaa aagatggcaa gatatagaag aattgctgtt
    11701 agcaggcata aatgtctaca ctactgtaaa tgtacaacat ttagaaagtc taaatgacat
    11761 tgttgaggta attacaaacg tatcagttaa agagactata ccagataagt ttttggatac
    11821 aaatacacag ttagaactta tagatgttga acctgatgta cttcttgaaa ggttcaatga
    11881 aggtaagata tataagaaag aacaagctac tagagcaaaa aataattttt ttataaaaga
    11941 taacctggtt gcacttagag aaatcgcact tagaaaaaca gcagagagag ttaataaaga
    12001 agttcaaatg accagactat caaagggtga tgtaactgta atacctacat cagatacact
    12061 tcttgcatgt ataagtccat ctccatcttc agcaaaagtt attagaactg catccagaat
    12121 atcagacagt acatttgcaa aatggatagc tttatatgtt gaaactccaa acacagcaag
    12181 acttccattt gatgaacaaa aacaactaca aaataaccta aaattagcta agaaattagg
    12241 tggagaaata attgttttac atggtgaaaa tataatagag caaatactta gaattgcaaa
    12301 actgagaaat gtaacaaaaa ttgtaatagg tagaaatcat tcaagtaata aaagatttag
    12361 taaaagattt aaaaaagata tagttgacaa attaattgat gaagttgatt atatagatat
    12421 acatataatt ccatataaat ttgcctcaga tgttaaatac agacctaaaa aggataaatc
    12481 atcaataaaa tctaaattta aaattagcaa agttgatttt ataaaactta tatttattac
    12541 tttgatgata agtattttag catatgcagt acaaagcatg ggatttataa gagaaaatat
    12601 attgttaata tatatgttgg gtgtagtttt agtttctatg tggactaaag ggtatagtac
    12661 aggtataata agttctgtat ttaatatagt tcttttaaat tattttttta cagcaccatt
    12721 atatacatta tctatagcag attcaaacta tatagtaaca ctggttgtat tctcaatagt
    12781 aggtataata actagcactc ttacgtctaa gatacagcat gaagcagaaa ctgctgctaa
    12841 aagagaagaa aatacaaaaa tgatatatca aataattaag ggatttttaa gattatcaaa
    12901 taaagatgat atagtaaaca aaggtataga acttttgtct cttagcttaa gtagagatgt
    12961 aatttgttat ttaaatgtag ataagcataa taaatcaaaa ctttacaaaa aaaatactaa
    13021 taataaggat aaaaatgatt tggatagtga agatgaaaaa gctgttgcaa gttgggtttt
    13081 atccaattca acagtggcag gaaatgacac ggatacactt cctggttcaa agggatacta
    13141 tataccaatt gtaggaatga atttaacttt aggagtagta ggaatatcat gtattgattc
    13201 aaaattggat acagaagata taagcttaat tgaaacaata attgctcaaa tggcaatagc
    13261 gcttgataga gaaatcttgt cagaagctaa agaaaatacc aatcttgaga ttgaaaggga
    13321 aagattaaga agtaatcttt taagagcagt ttcgcatgac cttagaactc cactagcagg
    13381 aatatctggt gcagtaagta caattataaa aaacaagggt actataggtc aagatataat
    13441 agatgaatta cttagtggtg tatatgaaga tactcagtgg ttaataagac ttgttgaaaa
    13501 tttacttagt atgaccaaga tagatgaagg gaaattggaa gttaaaaaac attctgaact
    13561 ggttgaggaa attatatcag aagcgttaca aaaaataaaa aaaagaattg aaaatgcact
    13621 tatagatatt aatataccag aacagatatt atttgttcct atggatgcaa aattaataga
    13681 acaagtttta attaatttaa tagataattc tttgaaatat tcaaaggaag attgtaagat
    13741 agagataaat gtatacgaga aagatgatta tgtttggttt gaagtatctg ataatggtcc
    13801 tggtatatca aaggaactta aaaagcatat ctttgacaga ttttttactg gagaagaagg
    13861 agctaaagat tccagaaagg gtgttggact tggattatca atttgtaaat ctataattca
    13921 agctcataaa ggtgaaatta tggtagaaaa caataaagat aagggttcaa cttttaagtt
    13981 tagtttgcct aaggaaaatg aatagtttta aattttaaaa ttagttttgg aggaagaaat
    14041 gagtaaaaaa cttatattgt tagtagagga tgataagaca ataagaaaat ttatatctac
    14101 tgcactttta acacaggatt atgatgtcaa ggaggctata actggaaaag aaggtatatc
    14161 tattgctgtc tcatattctc cagatgttgt tcttttagat ttaggcttag aagatatgga
    14221 tggaatagag gtaataaaag ctatcagaca attttcaaat ataccaataa ttgtagtttc
    14281 agctagagag caagatagag ataaggtaga agtatttgat gcaggggcag atgattactt
    14341 aacaaaacca ttctccatag tagagttatt agcaagagta agagtcgcat ttagacattc
    14401 acaagtagaa gctcaacaaa aagatgatgt taaatctatg tttgaagtag ataaattatt
    14461 gattgatttt gataaaagaa aagttattgt tgatgatgtt gaagtccatt tgacacctat
    14521 tgaatataat attctttcat tacttgcaaa gcatcatgga aaagtgctta ctcataattt
    14581 tataataaaa gaaatatggg gtagtgttat agggaatgag actaagtctt taagggtctt
    14641 tatggcaaca ttaagacgaa aaatagaaaa acaacctgca aacccaagat atataattac
    14701 agaagttggt gtaggataca gattaaatga tgaatagttg taatatatta attattagat
    14761 tatgtgctta ttaatatata ttaaaattat atagtttagt taaaataaga atgaagtgta
    14821 tgtgcttgtt gtcagtttag cacatgcatt ttatttttta gcttttttag tatcaataat
    14881 atgaaatatg ttttaaaata agtatatagt gtaatctgta ataaaaactt tggttaaata
    14941 at
//
LOCUS       DACTZW010000098        14863 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.098, whole genome shotgun sequence.
ACCESSION   DACTZW010000098 DACTZW010000000
VERSION     DACTZW010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14863
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.098"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            46..612
                     /locus_tag="JAM15_16185"
     CDS             46..612
                     /locus_tag="JAM15_16185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HAT6799790.1"
                     /translation="MRKLEEILEYNKSFVENKEYEQYVTSKHPNKKIVVLSCMDTRLT
                     ELLPKAMNLKNGDVKLIKNAGATIMHPFGSIMRSVLVAIYEFDVDEVMVVGHHGCGMC
                     NVDTDKLLGKILDRGISNDVILTLRSAGIDTKQWLHGFDSAEESVKDSIDLIKGHPLI
                     PDGIIVHGLIISPETGKLDVVINGYEDK"
     gene            917..1378
                     /locus_tag="JAM15_16190"
     CDS             917..1378
                     /locus_tag="JAM15_16190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAT6799791.1"
                     /translation="MNSNSEEKLNDVFLQLMRIYFIRTHFYFDKLGLYHGQPQILFSL
                     KMKDGQSQKELADKRKVKASTTTVMIKRMEKAGLVERKQDEKDQRVSRIFLTDKGLEI
                     CNKVEEFNKELEREFFLGFSEEEKIVLRRLLMQVRDNLKAGCHKHEDEKYF"
     gene            1446..3692
                     /locus_tag="JAM15_16195"
     CDS             1446..3692
                     /locus_tag="JAM15_16195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6799792.1"
                     /translation="MFKLIKYLKKSALSIVIIVCLLVIQAVCDLSLPEYTSNIVNVGI
                     QQGGVENSVPSVIRESELNKITLFMDKSSKDKVLDNYTLLNKKDYVKYKDKYPGLKDE
                     SLYELNTKDKDTIDDLNVIFGKAILIVSGLEGDSKEVKAMKAQLMSKLPPQATQSGDV
                     DIFKLLSAMPKEQLDTLTKEMSKGFESMPESMITQSSVSYVRSEYEKIGIDTEKTQNN
                     YILFTGAKMLGIAMISMVATITVGFLAARVAASVGRNLRSGVFRKVMSFSNTEMNEFS
                     TASLITRSTNDIQQIQMLMVMLLRIVFYAPIMAIGGVIKVLNTNTSMAWIIAVAVVAI
                     LSLIVVLFSVVMPKFKLVQKLVDKLNLVSREIITGIPVIRAFSTEKHEEERFDKANKN
                     LTKTNLFVNRVMTCMMPAMMLIMNLITVLIVWRGAYSVDSGAMQVGDMMAFIQYTMQI
                     IMSFLMISMVSIMLPRASVSATRIDEVLVSDISIKDPEKSEAQEFKEDKKGLVEFKNV
                     SFMYPDAEEPILTNISFTAKPGETTAFIGSTGSGKSTLINLIPRFFDVTEGEILLGGV
                     NIKNVSQHDLREKIGYVPQKGVLFSGTIESNLKYGRKDATDEEMRTAAEIAQATEFID
                     SKPEAFKTEISQGGTNVSGGQKQRLSIARAIAKNPEVYIFDDSFSALDLKTDAALRKA
                     LKSKTAESTVLIVAQRISTILNAEQIIVLNEGEIVGIGTHKELLKNCEVYEQIALSQL
                     SKEELANE"
     gene            3685..5517
                     /locus_tag="JAM15_16200"
     CDS             3685..5517
                     /locus_tag="JAM15_16200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6799793.1"
                     /translation="MSRMGRGPMGKSMGAGQKANDFKGTMRKLIAYLSKFKISIILVI
                     VFAIGSASFSIVGPKILGKATTKIFEGLVSKVSGGNVGIDFNAIGKILTFLLFLYLIS
                     ALFSFIQGFIMSGISQKVSYNLRKEISAKLDRLPMKYFDTKTHGEILSRITNDIDTLN
                     QSLNQSMTQLITSVTTMIGVLIMMLSISGIMTLVAVLILPISMFVISRIIKKSQKYFR
                     YQQEYLGNVNGQVEETYSGQTIVKAFNREDEVIEEFDKLNDSLYNSAWKSQFLSGIMQ
                     PLMMFIGNLGYVMVSILGGWLAIKKTIEVGDIQSFIQYVRNFTQPMTQIAQVANLLQS
                     TAAASERVFEFLEEEEEVQIVENAVSIDGLEGKIDFENVNFGYNPNKTIINDFSVNVK
                     PGQKVAIVGPTGAGKTTIVKLLMRFYDVNSGSILIDGHNIKDFNRSELREMFGMVLQD
                     TWLFSGSIMENIRYGKLNATDEEVIEAAKSAHVHRFIKTLPDGYKMKLNEEASNVSQG
                     QKQLLTIARAILADPKILILDEATSSVDTRTEVLIQKAMDNLMEGRTSFVIAHRLSTI
                     RDADMILVMNEGDIVEQGNHEELLKKGGFYANLYNSQFEEDEAM"
     gene            6242..7513
                     /gene="hflX"
                     /locus_tag="JAM15_16205"
     CDS             6242..7513
                     /gene="hflX"
                     /locus_tag="JAM15_16205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HAT6799794.1"
                     /translation="MAKKGITVGLNINNKSEDFNELMIELENLCSACDIDVVGSITQN
                     AKQVNRAFYIGTGKVEEILNLIKKENIEIVIFYNELSTSQLKNLEEKLNCEIIDRTAL
                     ILDIFAQRAKTREAKLQVEVASLKYMLPRLIGSNENLGRQSGGVGTKNRGSGEKKLEL
                     DRRRIEEKITSLNRELDDLKFQRETQRSMRRKSNLPNVALVGYTNAGKSSIMNKLVDI
                     FKNSEEKKVFEKNMLFATLETSVRNIVLANNKEFLLSDTVGFVSNLPHDLVKAFRSTL
                     EEACEADVLLHVIDISNPSYKSHIKVTEDTLKQIGADGIPMIHVYNKIDLIDVEVLDR
                     ILDSIDKEGIFVSVKKDINIDKMIKCICDSIFKDCVRCKFLIPYDKGHVVSYFNENTS
                     IINTEYREDGAILDVECSNIEYNKYKKYALE"
     gene            7746..8243
                     /locus_tag="JAM15_16210"
     CDS             7746..8243
                     /locus_tag="JAM15_16210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAT6799795.1"
                     /translation="MDAETLMKKYMVDDDSRKQAIFASIFVMQNKLQTTCDKLDPELT
                     MKQWLLLAIADSVDETLTLTKLGELMGCSRQNVKKLAIALEKKGFIQIEQNEKDSRAI
                     CLVTKDRVQEYSKKVRGIQEKVLQLLFEDFTEKKVEQLFFGIMKLSIGIENVKNYVEN
                     NDVGE"
     gene            8293..8817
                     /locus_tag="JAM15_16215"
     CDS             8293..8817
                     /locus_tag="JAM15_16215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HAT6799796.1"
                     /translation="MKSVVVIYKSKYGSTKKYAKWLSELLSCDIFETKNINIEKVMKY
                     DTIILGGGLYACNIAGISFLKKNYKDLQKKNLVVFGVGAAPYDDEVIKKLREVNFKDE
                     LNKVPCFYCRGAWDETKMSFIDYTLCSFFKKSIAKKERQGLKPAEAPLLSGEAFDWCN
                     KENLTPILDYIRKL"
     gene            9129..10493
                     /locus_tag="JAM15_16220"
     CDS             9129..10493
                     /locus_tag="JAM15_16220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HAT6799797.1"
                     /translation="MDIKELVKMQRKYYNTGKTRDISFRIEQLKKLKLVVSQNEEKIL
                     LALKKDLNKSDFEGFMTEVGMFYSELNFAIKNIRKWSKIKRVKSSMVNFPSISKVVPQ
                     PYGVTLIMSPWNYPFQLALIPLVWSLAAGNCVILKPSEYSVSTSSVVKDIVEDTFSKE
                     YVAVVQGSQEESEKLLLERFDYIFFTGSSNIGKIIMKSASEHLTPITLELGGKSPCII
                     LKDANIDLTAKRLTWGKLINAGQTCVAPDYVLVHEDRKNELIEKIKYYTNKYFGDNPC
                     NNEQFPKIINQRHFNRILSLIDKDKIVYGGNYNKETLKIEPTIVDNVNWDDNIMKEEI
                     FGPIFPILTYKDLDEVIQKIIQMPNPLALYIFTKNKYLENKLLEMIPAGGCCINDTVT
                     HIATNYLPFGGIGESGMGSYHGKAGFDTFTHYKSVLKKLNLDVPIRYAPYDNKLIKVL
                     KKIM"
     gene            10632..11798
                     /locus_tag="JAM15_16225"
     CDS             10632..11798
                     /locus_tag="JAM15_16225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAT6799798.1"
                     /translation="MKINWNTKYTTIAIYTFIIAASSIIFYLVSSQIDVFSNNLDAIF
                     TTLQPFIIGFAIAYLLNFILKFYEDRIFIKSEKLKKLKQSSKRGLGLLLTYATATLIL
                     YLFMHFVLPQVIESIVGLANDIPMYVNNATKLIDKLMTDLNLDEQYFNLAVDKWNEFV
                     TYIIKFVTDLIPILGSMLKNVASSIWNIVLGLIVSVYLLIDKEKFYGLSKKITYAVFT
                     EKQAARILELTHRSNYTFGRFLGGKILDSFIIGILTFVILTLVKMPYTLLISVIIGIT
                     NIIPFFGPLFGAIPSTLIVMFVSPIKAFWLLLIILIIQQIDGNIIGPKILGDSIGISA
                     FWILFSLLVAGKLLGFIGMVIGVPMFAVIYSIIKDIVESKLDKKGLPTDTSDYM"
     gene            11915..12697
                     /locus_tag="JAM15_16230"
     CDS             11915..12697
                     /locus_tag="JAM15_16230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HAT6799799.1"
                     /translation="MAFIECKFKSKYTGGETDIIVILPVANGKELFSGKEIYDFEGKF
                     KTLYLFHGLEDDQSSWIRYTNVEHYAKNKNIALVIPRVETSFYTDMAYGHQYFTFVSE
                     ELPKFVRAIFPLSDKREDNFVAGMSMGGYGALKLALSKPKEFSAVASFSGSPDMIHEL
                     ENQQIETNADILFHDFGRPEDARNSENDLLYILKNLKERNEDIPKIYQFCGDRDFLYK
                     NNQMFKKYAESLGVDVEYEECVGGHEWRLWNLWIKKFIDIIG"
     gene            complement(12816..13469)
                     /locus_tag="JAM15_16235"
     CDS             complement(12816..13469)
                     /locus_tag="JAM15_16235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAT6799800.1"
                     /translation="MSKSEKGKETKASIISAARELFFEQGYHKTTTRQIAERANINLG
                     LISYYFSSKSEIGAIIYEDIRNEMQSLIYNYHEEGTMMMFFLAMNADLCFLLKNEAYR
                     NFYLDIAYEEAILSYQRSVTEMVMKRYVNDKESIEHDELILSCIGILAMKPEIIRVYT
                     SHKYDISSQAVIKHFTKQFLINLGHSTDLCEEILEELSKYYIDIVDNFTPIITRVRT"
     gene            complement(13493..14857)
                     /locus_tag="JAM15_16240"
     CDS             complement(13493..14857)
                     /locus_tag="JAM15_16240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HAT6799801.1"
                     /translation="MLLLIVTCAIYIWIGFYFSKKVKTASDFLIAGRNLPLPILAATI
                     AATSFGGGCLVGGVQWGAERGLWVGMYSTIGAALACFINAFFAGKLRSLSCDITPADY
                     IETRYGHSVFLRAYQSLVTPISILAIMGSQLISFGSVSTAFGIPYDIAVIIGVIVIII
                     YTYTSGMWGVAVSAFIQLAICIVFLPIVAYISLKLVGDNPLLMLQSMVKEPFFPGNKS
                     ISDFMYTVLPLVLGSIFSYESFLRYQCADNAKNAVKSSVIAGFILLFLAFPIGIIGAI
                     GGSLFPNISSVQVLPQMISTTLPPLISVLFLAAILAAIMSTADSLMTSMSAIISRDIY
                     NKLLHPNIEFNDLKNTLKYSQIASALTAIIGAIIALKFDSLLELLFWPAPLCTGVIFA
                     PFVIGLCWKGATKKGAIYAVIVSVILALLNMIGILTVFDRILVPIIGGSITIFIVSKF
                     SKKD"
BASE COUNT         5766 a         1651 c         2529 g         4917 t
ORIGIN      
        1 agtgatataa taataaaaaa atttttaaag agggtgatat tacatatgag aaaacttgaa
       61 gagatactag agtataataa atcatttgta gagaacaaag aatatgaaca atatgtgaca
      121 tcaaaacatc caaataaaaa aatagtagtc ttatcttgta tggatacaag attaactgag
      181 cttttgccca aggctatgaa tttgaaaaat ggagatgtga aactaataaa aaatgcagga
      241 gctactataa tgcatccttt tggaagtatt atgagaagtg ttttagttgc aatttacgaa
      301 tttgatgtag atgaggttat ggttgtaggt catcatggat gtggtatgtg taatgttgat
      361 acggataagt tacttggtaa aattttagat agaggaatat ctaatgatgt aatacttaca
      421 cttcgtagtg ctggaattga tacaaaacaa tggttacatg gattcgattc tgcagaagaa
      481 tctgtaaaag atagtattga tttaataaaa gggcatcctt taattccaga tggtattatt
      541 gtacatggtc taattatatc accagaaact gggaagttag atgttgttat aaatggatat
      601 gaagataaat agagtattgt aatgttatat aatcaagata ctgttgagta agatgttgtt
      661 tcaaaattta ttttgggaca acttttttat ttgaaaatat atgaaaaggt ttattttaag
      721 ctttacaata aaaaatataa gtagctgact aattaaaaat cttactatta tttattaaaa
      781 ttataactat atgatataaa aatatttaat aaatgaaatt tatatgaatt ttttataaat
      841 atattgaaaa aatgcatgca gtatagtaaa ataatgctta gccgactaag taatataaaa
      901 aataaggagg gcaagtatga atagcaattc tgaagaaaaa ttaaatgatg ttttcttgca
      961 attaatgcga atatatttta taagaactca tttttatttt gataaattag gcttatatca
     1021 tggtcaaccc caaatacttt tttctttaaa gatgaaagat gggcaaagtc aaaaagaatt
     1081 agcagataaa aggaaagtaa aagcatctac aactacagtt atgataaaga ggatggaaaa
     1141 agctggactt gtggaaagaa aacaagatga aaaggaccaa agagtatcta ggattttttt
     1201 gacagacaaa ggtttagaaa tatgtaataa agttgaagaa tttaacaagg aattggaaag
     1261 agagtttttt ttaggattta gtgaagaaga aaaaatagta cttagaagac ttctaatgca
     1321 agtacgagat aatttaaaag caggatgtca taagcatgaa gatgaaaaat atttttaaag
     1381 tttaaaataa tgtttttcaa tttaatgtta ttagactaat taatattaca gaagggaaga
     1441 aatgtatgtt taaattaatt aaatatttaa agaaatcggc attatcaata gtaataatag
     1501 tctgtctatt ggtaattcaa gcggtatgtg acctttcttt accagaatac acatccaata
     1561 tagtaaatgt aggtatacaa caaggtggag tagaaaactc tgttccatct gtgattagag
     1621 agagtgaatt aaataaaatt actttattta tggataaaag tagtaaggat aaagtactag
     1681 ataattatac tttgctgaat aaaaaggatt atgttaagta taaagataag tacccaggtc
     1741 taaaagatga atctctttat gagttaaata ctaaagacaa agacactata gatgatttaa
     1801 atgttatttt tggtaaagct attttaatag tatcagggct tgagggcgat agtaaagagg
     1861 taaaagctat gaaagctcag ttaatgagta aacttccacc acaagctact caaagtggag
     1921 atgttgatat atttaaattg ttatcagcaa tgccaaagga acagttagat acattgacta
     1981 aagagatgag caaaggcttt gaaagtatgc cagagagtat gataacacaa agctctgttt
     2041 catatgtaag gtcagaatat gagaaaatag gtattgatac agaaaaaact caaaataatt
     2101 atatattatt tactggtgct aaaatgcttg gtatagcaat gattagtatg gtagctacaa
     2161 taacagtagg atttttagca gcaagagtag cagcaagtgt aggtagaaat ttaagaagtg
     2221 gagtatttag aaaagttatg tcattttcaa atactgaaat gaatgaattt tctacagctt
     2281 cattaattac tcgtagtaca aatgatattc aacagataca aatgttgatg gttatgttgc
     2341 ttagaatagt attctatgca cctataatgg ctataggtgg agtgataaag gttttaaaca
     2401 caaatacttc aatggcctgg attatagcag tagcagtagt tgctatctta tcattaattg
     2461 tagtgttatt ctcagtggtt atgcctaagt ttaaactggt tcaaaagctt gttgataagt
     2521 taaacttagt aagccgtgaa ataattactg gtattccagt tatcagagct tttagtactg
     2581 aaaaacatga agaagaaaga tttgataaag caaataaaaa tttaactaaa acaaatcttt
     2641 ttgtaaatag agttatgaca tgtatgatgc ctgctatgat gcttataatg aaccttatca
     2701 cagttcttat agtttggaga ggtgcataca gtgttgattc tggagcaatg caagttggag
     2761 atatgatggc atttatacaa tatacaatgc aaataataat gtcattctta atgatatcaa
     2821 tggtatctat tatgcttcca agagcatccg tttcagctac acgtatagat gaagtattag
     2881 tgtcagatat aagcataaaa gacccagaaa aatcagaggc acaagagttt aaggaagata
     2941 aaaagggtct tgttgaattt aaaaatgttt cgttcatgta tccagacgca gaagaaccta
     3001 tattaacaaa tatatctttt acagcaaagc caggagaaac aactgccttt ataggaagta
     3061 ctggtagtgg taagtcaact cttataaatt taattcctcg tttctttgat gttactgaag
     3121 gagaaatatt acttggtgga gttaatataa aaaatgtttc tcaacatgat ttaagggaaa
     3181 aaattggata tgtacctcaa aagggagtat tgttttctgg tactatagaa tccaacttaa
     3241 aatatggtag aaaagacgca acagatgaag aaatgagaac agcagctgaa atagctcaag
     3301 ctacagaatt tatagattct aaaccggaag cttttaaaac tgaaatttct caaggtggaa
     3361 caaatgtatc tggaggtcaa aaacaaagac tttctattgc aagagcaata gcaaaaaatc
     3421 cagaagttta tatatttgat gatagttttt cagcacttga cttaaaaact gatgcagctc
     3481 ttcgtaaggc tttaaaatca aaaactgctg aaagtacagt tctaatagtt gcacaaagaa
     3541 ttagtactat cttaaatgca gaacagataa ttgttttaaa tgagggagaa atagttggaa
     3601 taggaacaca taaagagctt ctaaaaaatt gcgaagttta tgagcaaata gctttatcac
     3661 aactttcaaa ggaggagcta gctaatgagt agaatgggaa gaggtcctat gggaaaatct
     3721 atgggagcag gacaaaaagc aaatgacttt aaagggacta tgcgaaaact aattgcatat
     3781 ttatctaaat ttaaaatatc aataatttta gtaattgtat ttgctattgg tagtgcatcg
     3841 ttttctatag taggtccaaa aattttagga aaggcaacta caaagatatt tgaagggtta
     3901 gtgagtaaag tttctggagg aaacgtaggt atagatttta atgcaattgg aaaaatctta
     3961 acctttttac ttttccttta tttgataagt gcactgttct cttttataca aggatttata
     4021 atgagtggaa tttctcaaaa agtatcctat aatttaagaa aagagatttc agcaaaattg
     4081 gatagattac caatgaagta ttttgatact aagacgcatg gtgaaatatt atcgagaatt
     4141 acgaatgata tagatacttt aaatcagagt ttaaatcaaa gtatgacaca gcttataaca
     4201 tcagtaacaa ctatgatagg tgttttgata atgatgttat ctataagtgg aattatgaca
     4261 ttagtggcag ttttaatatt accaatatca atgtttgtaa tttcaagaat aataaagaaa
     4321 tcacaaaaat actttagata tcaacaagaa tatttaggaa atgtaaatgg tcaagttgag
     4381 gaaacttata gtggccaaac aatagtgaaa gcatttaatc gtgaagatga agtaattgaa
     4441 gagtttgata aactaaatga tagcctgtat aattcagcgt ggaaatctca atttttatca
     4501 ggtataatgc aaccacttat gatgtttatt ggaaacttgg gatatgtaat ggtatcaatc
     4561 ctaggaggtt ggcttgcaat taagaaaaca attgaggttg gtgacataca gtcatttata
     4621 caatatgtaa gaaactttac acagccaatg actcagattg cacaggttgc caatttattg
     4681 caatcaacag cagcagcttc tgaaagagta tttgagtttt tagaagagga agaagaagtc
     4741 caaattgttg aaaatgcagt ttcaatagat ggtttagaag gtaaaattga ttttgaaaat
     4801 gtcaactttg gatataaccc aaacaagact ataataaatg atttctcagt aaatgttaaa
     4861 cctggtcaaa aagttgctat tgttggacct acaggagcag gtaaaactac aatagttaaa
     4921 ctgttaatga gattttatga tgttaatagc ggttcaatac tgattgatgg tcataatatt
     4981 aaagatttta atcgtagtga gcttagagaa atgtttggta tggttcttca agatacatgg
     5041 ttatttagtg gttcaattat ggaaaatata agatatggta agttgaatgc tacagatgaa
     5101 gaagttatag aggctgctaa atctgcacat gttcatagat ttattaagac attaccagat
     5161 ggatataaga tgaaattaaa tgaagaagca agtaatgttt ctcaaggtca aaaacaatta
     5221 ttgactatag ctcgtgctat tttagctgat cctaaaattt taatattaga tgaagctaca
     5281 agttctgtcg atactagaac agaagtattg attcaaaaag ctatggataa tcttatggaa
     5341 ggtagaacaa gttttgttat agcccacaga ttatcaacta tacgtgatgc tgatatgatt
     5401 cttgtaatga atgaaggaga tatagttgaa caaggaaatc atgaagaact tctaaagaaa
     5461 ggcggattct atgccaatct ttacaattct caatttgaag aagatgaagc aatgtaacaa
     5521 aaaactatct tagcatagac atgtaattaa taagataaaa taaatgaggg tgccttaaaa
     5581 tgaacttttt agttcataag gcactctttt gtgtatgaaa taaaatgtat ttttatcatt
     5641 ttaacaatga aaaagaggat tctctatatt ttgagatagc cacataattt tatgccttta
     5701 caaagtgttt attttattat aatatgtagt aaggaaaatg ttggaggtga ttatcaaaat
     5761 gtatatttaa ttttattctt taaattttat tataaataga atttaatttt aatagttgat
     5821 gattatattg aagtatatgt ttttattact tttattaatc atgcaaataa ctacttaaat
     5881 ttaagaatag ggttaaatat aaaatgataa ttacatataa gttaattaaa ctaatgtatt
     5941 tttaatatat atttagaatt ttaatccttc ttatgatata agtagcttgt tttgtattac
     6001 ttagatttgt aaggagtttt tttattgaaa aaactgcata atatatttgg gaggaggtgt
     6061 aagaaagtga ttttttatat aagattgaga aaataatgca cgattatggt tattataata
     6121 gtaaataaga agtgtcattt aaggataaga taaaaagcaa aattcttgat gaatttaatt
     6181 atagagccat aatcttgtgc tatagattaa ataaaaaata gcagataagg agaatatgga
     6241 tatggcgaaa aaaggaataa cagtaggatt aaacataaat aataaatctg aggactttaa
     6301 tgaactaatg attgaacttg aaaacttatg ttcagcatgt gatattgatg ttgtagggag
     6361 tataactcaa aatgcaaagc aggttaatag agcattttac attgggacag gtaaagttga
     6421 ggaaatatta aacttaataa agaaagaaaa catagagata gttatatttt acaatgaact
     6481 ttctacatca caactaaaaa atcttgaaga aaagcttaat tgtgaaatta tagatagaac
     6541 agcattgata cttgatatat ttgcacaaag ggcaaaaact agagaagcta aacttcaagt
     6601 agaagtagca agtttaaaat atatgttacc aagacttata ggttcaaatg aaaatttagg
     6661 acgtcaaagt ggtggagttg gtactaaaaa tagaggttct ggtgagaaaa aattagaact
     6721 tgaccgtaga agaatagaag aaaagataac atctttaaat agggagttgg atgatttaaa
     6781 attccaaaga gaaactcaaa gaagtatgag aagaaaatca aatcttccaa atgtagctct
     6841 agtcgggtat acaaatgctg gtaaatcttc aataatgaat aaactagtag atatatttaa
     6901 aaactctgaa gaaaagaaag tgtttgagaa aaacatgtta tttgctacac ttgaaacttc
     6961 tgtcagaaat atagttcttg caaataacaa agaattttta ttatctgata ctgttggttt
     7021 tgtaagtaat ctaccacatg acttagtaaa agcatttagg tcaacattag aagaagcatg
     7081 tgaggcagac gtactgttac atgttattga tatttcaaat ccaagctata aaagtcatat
     7141 taaagtgaca gaagatactt taaaacaaat aggtgcagat ggtataccta tgatacatgt
     7201 gtataataaa attgatttaa tagatgtaga agtattggat agaattttag atagtatcga
     7261 taaagaaggt atatttgttt cagttaaaaa agatataaat atagataaaa tgataaaatg
     7321 tatttgtgat agcatattta aagattgtgt aagatgtaag ttcttaattc catatgataa
     7381 aggtcatgta gtttcttatt ttaacgaaaa tacgagcatt ataaatacag aatacagaga
     7441 agatggagct attttagatg tagaatgtag caatatagaa tataataagt ataaaaagta
     7501 tgctttagag taaattttga aaaacttatt atagcctaaa atatatttaa tttataattt
     7561 attataaatt gattgtaaat atgattttat gaaacggtat agctataatg ctatgccgtt
     7621 ttgccattta taataaaaat aaatttattg acacaatagt aactaattac tataatataa
     7681 agtaactagt tactatttaa aattatcaaa aaattaaaat ctaagataaa gagaagtgta
     7741 taataatgga tgcagaaact ttaatgaaaa aatatatggt agatgatgat agtagaaaac
     7801 aagctatatt tgcaagtata tttgtaatgc aaaataaact tcaaactaca tgtgataaat
     7861 tagacccaga attaacaatg aaacaatggt tacttttagc tattgcggac tctgtagatg
     7921 aaactcttac attaaccaaa cttggagaat taatggggtg ctcaagacaa aatgtaaaaa
     7981 aactagctat tgctttagaa aagaaaggtt ttatacaaat tgagcaaaat gaaaaagatt
     8041 caagagctat ctgtcttgtg acaaaagata gagtgcaaga gtattctaaa aaagtaagag
     8101 gtatacagga aaaagtatta cagcttttat ttgaagattt tacagagaaa aaagtggaac
     8161 agttattttt tggaattatg aaattaagta taggaattga aaatgtgaaa aattatgtag
     8221 aaaataatga cgttggagaa taagcaagta tcaaatcaac tttgtatgac atcagagagg
     8281 ggggtaattt atatgaaaag tgtagtagtg atttataaga gtaagtatgg ttcaacaaaa
     8341 aaatatgcta aatggctttc agaattattg tcttgtgata tttttgaaac taagaatatt
     8401 aatatagaaa aggttatgaa gtatgatacg attattttag gaggaggtct ttatgcttgt
     8461 aatatagcgg gaatttcttt cttaaaaaaa aattataaag atttgcagaa aaaaaattta
     8521 gtagtatttg gcgtaggagc tgctccatat gatgatgaag taataaagaa attaagagaa
     8581 gtaaacttta aggatgaatt aaacaaagtt ccttgctttt attgtcgtgg ggcatgggat
     8641 gagacaaaaa tgtcttttat agattatact ctttgtagtt tttttaaaaa atctatagct
     8701 aaaaaagaac gtcaaggtct taaaccagca gaagcacctt tattgtctgg agaagccttt
     8761 gattggtgta ataaagaaaa tttaactcca atacttgatt atataagaaa actttaagag
     8821 gtatatattt ataattattt attatctaaa gttagatttc atagaaactt actagacatt
     8881 atttataaaa taatattatt aaagatggat aatttaattg tttcaataag gttataattt
     8941 taaaaaatgt ttattttaaa ataaactatt ttataagctt acttatactt aataaggggc
     9001 tttttttatt ggaagattta tgttatattg agatgaattt attatgatat aaaaaataat
     9061 gttaggataa atttaaatct ttttctaaaa atgtattagt ataattctta aagaaaggat
     9121 ttttaacaat ggatataaaa gagttagtta aaatgcaaag aaaatattat aatacaggta
     9181 aaacaagaga tatatcgttt cgtatagaac agttgaagaa acttaagtta gttgtatcac
     9241 aaaatgaaga aaaaatactt ttagcactaa agaaagattt aaataaatcg gattttgaag
     9301 gttttatgac agaggtaggc atgttttata gtgaattaaa ctttgctata aagaatataa
     9361 gaaaatggag caaaataaaa agagttaaat caagtatggt taattttcca tctatatcca
     9421 aagttgttcc acaaccttat ggtgttactc tcataatgtc accttggaat tatccatttc
     9481 aattagcact tataccatta gtttggtcat tagcagcagg gaattgtgtt atattaaaac
     9541 cttctgaata ttctgtgtca acatctagtg tagttaaaga catagttgaa gatacttttt
     9601 caaaagaata tgttgcagtt gttcaaggaa gtcaagaaga aagtgaaaag ttactattgg
     9661 aaagatttga ttatatattt tttacaggaa gtagtaatat tggtaaaata atcatgaaat
     9721 cagcatcaga gcatttaact cctattactt tagaacttgg aggaaaaagt ccttgtatca
     9781 ttttaaaaga tgctaatata gaccttactg ccaaaagact tacttgggga aaactaataa
     9841 atgcaggaca aacctgcgtg gctccagatt atgttttagt gcatgaagat agaaaaaatg
     9901 agttaataga gaaaataaaa tattatacta ataagtattt tggggataat ccatgtaata
     9961 atgagcaatt tcctaaaatc ataaatcaga gacattttaa tcggatatta tctcttattg
    10021 ataaagataa gatagtctat ggtggaaatt ataataagga gacattaaag atagagccaa
    10081 ctatagtaga caatgttaat tgggatgata atataatgaa ggaagaaata tttgggccta
    10141 tatttcccat tttaacatat aaagatttag atgaagtaat acaaaaaatt atacaaatgc
    10201 caaatccatt ggcactttat atttttacaa aaaataagta cctagaaaat aaacttttag
    10261 aaatgattcc agcaggcgga tgttgtatca atgatacagt tactcatata gctacgaatt
    10321 acttaccttt tggtggtatt ggtgaaagtg gtatgggctc atatcatgga aaagctggat
    10381 tcgatacatt tactcactat aagagtgtgt taaaaaaatt aaatttggat gtccctatta
    10441 gatatgctcc atacgataat aaattaatta aggttcttaa aaagataatg taggttatat
    10501 tgtagaataa taaatataaa taaaattgag tatttgtatt ctgaatatat tttattttta
    10561 atttggtata tttgttataa aagtagtgat tttgtgataa aatttaatta tatagaaata
    10621 aggaggaaaa aatgaaaatt aattggaata caaaatacac aacaatagca atttatacat
    10681 ttataatagc tgctagtagt attatatttt atctagtatc atcacaaatt gatgtatttt
    10741 ctaataattt agatgctata tttacaacat tacaaccttt tataatagga tttgctattg
    10801 catatcttct taattttatt ttaaagtttt atgaagacag aatttttata aaaagtgaga
    10861 aattaaaaaa actaaaacaa agttcaaaaa gaggcttggg tcttttatta acatatgcaa
    10921 cagctacatt gatactttac ttatttatgc atttcgtatt gccacaagta attgagagta
    10981 ttgttggact agcaaatgat atacctatgt atgtaaacaa tgcaactaag cttattgata
    11041 aattaatgac tgatttaaat cttgatgagc aatactttaa tttggcagtt gataagtgga
    11101 atgagtttgt tacatatatt ataaagtttg taacagattt aatcccaata ttaggaagta
    11161 tgttaaagaa tgtagcctct agtatatgga atattgtact aggattaatt gtttcagtat
    11221 acttattaat tgataaagaa aaattctatg gattaagcaa aaaaataact tatgcagtat
    11281 ttacagaaaa acaagctgcc agaattttag aattaactca tagaagtaac tatacatttg
    11341 gaagattttt aggtggcaaa atattagatt cattcattat aggtattcta acatttgtaa
    11401 tacttacatt agttaaaatg ccatatacat tattaatatc agttataatt ggtattacaa
    11461 atattatacc tttctttgga cctttatttg gagctatacc atctactcta atagtgatgt
    11521 ttgtatctcc tataaaagct ttctggttat tgttgattat attaataata caacagatag
    11581 atggaaatat tataggacct aaaatacttg gagattcaat tggtatatct gcattttgga
    11641 ttttgttctc cttattggtt gcaggaaaat tattaggttt tattggaatg gttataggag
    11701 ttccaatgtt tgcagtaatt tattctataa ttaaggatat tgttgaaagt aaattggaca
    11761 aaaagggatt accgacagat acttccgatt atatgtagct aaaaaatatt atgtataatt
    11821 aaaaatatat aaattaagca atatttaaag cactgagaaa gttaaactct tggtgctttt
    11881 tagatataaa attattatag aagaggtgtt ttttgtggca tttatagaat gtaaatttaa
    11941 atctaaatat actggaggag aaactgatat aattgtaatt ttgcctgtag caaatggaaa
    12001 agaacttttt agtggtaaag agatatatga ttttgaaggt aaatttaaaa cattatactt
    12061 atttcatggt ttagaagatg accaaagctc atggattaga tatactaatg tagagcatta
    12121 tgctaaaaat aaaaatatag ccctagtaat accaagagta gaaactagtt tttatacaga
    12181 tatggcgtat ggacaccaat attttacttt tgtaagcgag gaattaccta aatttgttag
    12241 agctatattt cctttatcag ataaaaggga agataacttt gtagctggta tgtctatggg
    12301 gggatatgga gctttaaaat tagcactttc aaaaccaaaa gagttttcgg cagttgcaag
    12361 tttttctggt tcgcctgata tgattcatga gttagaaaat caacaaatag aaaccaatgc
    12421 agacatttta tttcacgatt ttggtagacc agaagacgct agaaatagtg agaatgattt
    12481 actttacata cttaagaacc ttaaagaaag aaatgaagat attcctaaaa tttatcaatt
    12541 ttgtggtgat agagattttt tatataaaaa taatcagatg tttaaaaaat atgcagagtc
    12601 tctgggtgta gatgttgaat atgaagagtg tgtagggggg catgaatggc gtctttggaa
    12661 tttatggata aagaaattta tagatataat tgggtagtac acttatggta ttaacaggta
    12721 tactataaaa tatctttaaa tatgataaag actgaaatcc taaaatcaaa ttatgatttt
    12781 aaaatttcag tctataagaa tttaataaaa ttttattaag ttcttacacg agttattatt
    12841 ggagtaaaat tgtcaactat atctatatag tatttactca attcctctaa aatctcttcg
    12901 cataaatccg tactatgacc aagattaata agaaactgtt ttgtaaaatg ctttattaca
    12961 gcttgagaag atatatcgta cttgtgtgaa gtataaactc taattatttc aggtttcata
    13021 gcaagtatac caatacaaga aagtattaat tcatcatgtt ctatagattc tttatcatta
    13081 acatatcttt tcatgaccat ttcggttaca cttctttgat agcttaaaat agcttcttca
    13141 taagctatat ccaaataaaa atttctatat gcttcgtttt ttagaaggaa acaaaggtca
    13201 gcattcatag caagaaagaa catcatcata gtaccttctt catggtagtt atagattaaa
    13261 gactgcattt catttcttat atcttcatat attatagctc ctatttcgct tttacttgag
    13321 aagtaatagc ttattagacc taaatttata ttagctcttt ctgcaatttg cctagttgtt
    13381 gtcttatgat aaccttgctc aaaaaataat tctctagcag cacttataat actagctttt
    13441 gtttctttgc ccttttctga ttttgacata tttactgtgt atacctctct tttcaatctt
    13501 tttttgaaaa tttgctaact ataaatattg taatagaacc acctattata ggaaccaaaa
    13561 ttctgtcaaa tacagtaaga ataccaatca tatttaataa tgccaatata acacttacta
    13621 taacagcata gatagctcct ttttttgtag cgcctttcca gcaaagacca attacaaatg
    13681 gtgcaaatat tacacctgta cataatggag ccggccaaaa caataattct aataaactat
    13741 caaatttaag tgctatgatt gcacctatta tagctgtcaa agctgatgca atttgagaat
    13801 actttagagt attttttaaa tcattaaatt ctatattagg atgtaataat ttgttataaa
    13861 tatctcttga tataatagca ctcattgagg tcattaatga atcggcagta gacattatgg
    13921 cagccaatat agcagctaag aataatacag atattaaagg tggcaaagta gtcgatatca
    13981 tttgaggtaa aacctgaaca gatgatatgt ttggaaataa actaccacca atagctccaa
    14041 ttattcctat agggaaggca agaaataata gtataaatcc tgcaattaca ctacttttaa
    14101 ctgcattttt agcattatca gcacattgat atcttaaaaa actttcataa gaaaatattg
    14161 agcctaaaac taatggtaaa actgtataca taaaatcact aatcgattta tttcctggaa
    14221 agaatggttc ttttaccatt gattgtaaca taagtaaagg gttgtcgcca actaatttta
    14281 agcttatata agctactatt ggcaaaaaca ctatacaaat agcaagttga ataaatgctg
    14341 atactgcaac tccccacatt cctgatgtat aagtatatat aattataact ataactccta
    14401 taattacagc tatatcataa ggaataccaa atgcagtaga tacagaacca aaagaaatta
    14461 attgactacc cataatagct agtatagata ttggtgttac aagactttga taagctctta
    14521 aaaatacact atgaccatat ctagtttcaa tataatcagc aggtgttata tcacaagata
    14581 agcttcttaa ttttcctgcg aaaaaggcat ttataaagca agctaaagct gcacctatag
    14641 tagaatacat tccaacccaa agtcctcttt cagctcccca ttgaactcca ccaactaagc
    14701 accctcctcc aaaagatgta gcagcaatgg ttgcagctag tataggcaaa ggcagatttc
    14761 tacctgcgat taggaaatcg gatgctgttt taactttttt tgaaaaataa aaaccaatcc
    14821 atatgtatat tgcacacgta acaattaaaa gtaacatagt ctt
//
LOCUS       DACTZW010000099        14336 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.099, whole genome shotgun sequence.
ACCESSION   DACTZW010000099 DACTZW010000000
VERSION     DACTZW010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14336
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.099"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(121..657)
                     /locus_tag="JAM15_16245"
     CDS             complement(121..657)
                     /locus_tag="JAM15_16245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HAT6799802.1"
                     /translation="MEYKSPVYGIIAVPIEKIESNDYNPNAVAPPEMQLLYKSIKEDG
                     YTMPIVCYYNEEKDKYIIVDGFHRYRVMLENEDIYDRENGLLPVSVIDKSLDERMAST
                     IRHNRARGSHNVDLMSKIITELCEIGKSDEWISKHLGMEVDEILRLKQITGLAYLFKD
                     KEFGNAWIPFGSDIEEEN"
     gene            complement(675..1988)
                     /locus_tag="JAM15_16250"
     CDS             complement(675..1988)
                     /locus_tag="JAM15_16250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3440 domain-containing protein"
                     /protein_id="HAT6799803.1"
                     /translation="MDKRYLESDVFEAFQERLSYLFNEFDYIYVSFSGGKDSGLLLNL
                     VLDYKRKNNISSKIGVFHQDFEAQYSLTTEYVEKVFEENIEDIEPYWVCLPMATRTAV
                     GNYEMYWYPWDDEKEELWVREMPVKEYIINQKNNPFTYYKYKMRQESLAKQFGRWIRD
                     IHEGAKVVCLLGTRAAESLQRYCSIVNKQHGYKGKCWITKEFKNVWTASPIYDWEIED
                     IWLAHYKFDYDYNKIYDLFYKAGVAPRKMRVASPFNDSAKESLNLYRILDPDVWVKLV
                     ARVQGVNFTSIYGKTKAMGYRSVKLPYGHTWKSFTYFLLDTLPENIRNSYIKKFSTSI
                     EFWQNTGGGLSEIVIRELLRKGYKIELNGVSNHTKDKKSRVIFLDDIPDDTDDIKFTK
                     DIPSWKRMCYCILKNDHMCRFMGFGPTKEQRIRTEYIKKKYEKIH"
     gene            2324..2764
                     /locus_tag="JAM15_16255"
     CDS             2324..2764
                     /locus_tag="JAM15_16255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HAT6799804.1"
                     /translation="MYERMLDKSNKPCLSQIIEYIGKDGYARLCKLETYLETQYNLSR
                     ELRFPFGNNYGWGYKYSHKSFHLFYAFFEKGAFTVLIQIGDKQVPAVEKTLVSLTPKA
                     KELWVTRYTCGNNGGWIKYRILEDADLLDIIQYIRAKKSPPKQN"
     gene            complement(2949..3137)
                     /locus_tag="JAM15_16260"
     CDS             complement(2949..3137)
                     /locus_tag="JAM15_16260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799805.1"
                     /translation="MNKNNNLVIICMFIGMILGMAIGCAIGISKGNVGITMCYGLIFG
                     MIIGICIGTVIKNSNKKE"
     gene            4052..4447
                     /locus_tag="JAM15_16265"
     CDS             4052..4447
                     /locus_tag="JAM15_16265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799806.1"
                     /translation="MNILKMKKTGIFLGGVLFGTVGVKILSSDCVKKTCTRATAGALK
                     VKDSVLETTTKIQENVEDILAEAKEINEQEDLSTSKVNVVQDTLKCEQEVLKTETIKT
                     VEDTNSNNIKCEEIKDNVIEEKNNTCTTE"
     gene            4490..6589
                     /locus_tag="JAM15_16270"
     CDS             4490..6589
                     /locus_tag="JAM15_16270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HAT6799807.1"
                     /translation="MNFYIKHEIRGRIRFDLQLGKLNNKQSDTLLYYLTSINGITKAK
                     VYDRTGDAVIYYTGEREYIIREITKFSFNNSKIENLVPEHTSRELNNYYRDKLANKLL
                     VKSISKIFFPKSLRFFLIGLHSIKYFKKGLSSLLNKKIEISVLDATAIGISIFRKDIN
                     TAGSVMFLLGIGELLEEWTRKKSIDDLAQSMSLNIEKVWLKKDATEILVPISEIKEGD
                     LVSVTMGNMIPLDGVIVSGEAMVNQASLTGESLAVNKKEGSYIYAGTGIEQGNIVMCV
                     KEKAGTTRFQKIVTMIEESEKLKSSVESKFEHLADTLVPYSFLGSILTYAITRNPIKS
                     LSILMVDFSCALKLSIPISVLSAMRECNNHSIAVKGGKFLEGVACADTIVFDKTGTLT
                     KAQPTVSDIITFQNYNKKDMLRLAACLEEHFPHSIANAVVYEAEKQGLSHKEMHTEVE
                     YIIAHGISTKVDDKKVVIGSKHFVFEDEKCTIPDGEEDKYNNLSDEYSHLFMAISGKL
                     SAVICINDPLRKEAKYVISNLREYGIKKIVMMTGDSEKTAKSIASKVGVDEYYSEVLP
                     EDKANFVKSEKLKGRKVIMIGDGINDSPAISESDVGIAMSEGAEIAREISDITISADN
                     LNNLIVLKQISNKLMKRVDLSSKFIIGFNLGLILLGVSGFVRPSTSAFLHNASTVGIS
                     LNSMTNLLENTNTYNYY"
     gene            complement(6814..12024)
                     /locus_tag="JAM15_16275"
     CDS             complement(6814..12024)
                     /locus_tag="JAM15_16275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799808.1"
                     /translation="MANKLYSEIVNLLEEGRDELRKYDLKEKSILLFLGASGVGKSTC
                     INYLKGCVMEEKTDEETGQIYITAKDSAVEIGNGVYSKTLCPEVVDIANRNFSLCDCP
                     GFFDNRGAEYMIAGAMLVRETISTSSKVKGMVVILDYQSLLDSRHTLLIETGKNLKDM
                     LGDYAKYKENFFFLINKIPKTLIGNVTEEKIRNILEKAKEDLDSQEKDYDGCKELVYL
                     LNVALSDGVSIKLCNPLDKQPEKLLDEMKNLPETFEKTDLGLMLTASCKIEIQKAVDV
                     TYKDLEKLLVPYIESVKKGMEDSISILSSINSLKDKKTQLDKMYTDLCSRTNNMKELM
                     EFVQELSYGDGVQKVNILEETRLLLELNSYCSETHIVGLSELLKSLLKNTLEDTLKDI
                     KYWIAEEEYREEEAKKLEDAEYRIEKIQSCTYIKSYEKENVLSIYIPIPKVNLSDLTK
                     IISGYQLNILSSIYMYGDCELKIDCNMEKEVFSGKNIVLLTEKLCIPEGIYSINVSGK
                     DAEKLVGEGSIYDGMNGRNGNNAGTSGDILLSFKEIEKRGELKLYVDGGRGGNGQDGK
                     RGDTGITGEAGENAKIGSKKESKEFANVKGTKYYVVKAEKGKQGGTGGTGGNGGNAGL
                     GSKSGQVYLLGKASLLKGAISKKDGNHGLAGKGGSGGAGGAGGLGGIRGIYEETIRYI
                     GTSAPIDDSDRNYYYFDRYVFNHASNENQVADDGEKLNALYEKHKDWTISKREDSGLV
                     GAEGKDGRSGDALKEKELLKQEYSLSIDTFFYEFFERFGFSGIKGYRNLRLLCAVGIL
                     EADILELSHIYEIFHAVEKIEMQLNREILQKYYSFEKKNKAVLSLDDMNIKKEFYKEA
                     KEIYEYLINKLMQSDRIESFIGEKKNFSEWSMILFALEQKTAFYVQMIEESEIGGNRV
                     TDIRSLTDYLDKTLRELEQGKKDELKEGYFNTYKESILTQIESGNQQIEVLKNELENK
                     MLSVNAKMNLLIQEIIKMKEDEQEDIEELKKKQAKLEEQMKTQLILSGIQSALSLLTA
                     FSGVGQACLGAFDSAKSLKENLSAKEEEYKWTNRMVDFSDFKLDSDGMRFVLGEQLSE
                     DRKNALDKMTYNLAGVDEERRTKFDQIKEIIVKSIDDDNYADKADDIQRAKEGLSESE
                     YKEIYTKIQKKEIGMLEANYNNKQQKDKLAALEKSKQAIERQQKTSKIKNALSIGSSA
                     CSLINTAISGVNNCLNVKSSFESKIEVVKEAIKDKENNIKKLDELNTQMVEFKDKTLK
                     ESVIPFVEKFDSTVKNQDIFENEISKLKMKEVLTELSTKFESLKMENSEDISIIFKKV
                     QDMMETQIIITDKIDKKKDNLAMGELIYQMSGSGNQMNEYQKKLIHQIELNQVRYLCQ
                     VEAAAFQLWTFPFGSNIVNILNRCHVGITEDENEVINQAKEQNRQIREFLDQDAYQWQ
                     KTDNHILKVALTGSLDGKSRVGFENTYSLYDCNEEEVKKLLTGDEISFEVPLNQNFDA
                     IKYVTMYANIPNLRRNILEDSLKVKVHIHLYDSGYFSLYDDKKDVYYQYVFPQNYIDI
                     THGLDVKYNDSDSINSIWSSVEDKGIEKFKNAGLNSGRSPYSMAKISLKAHFNKKLSY
                     DSLTNEQKKKLESYFDKPSKYAWSESIDILKSLGYIDLKGILSKSWYEIKKDIDSDGE
                     IMKHFSILQVDLLERIIYEQTSILKENIPNLTIELVGCGIYVESEFNYLKQNDLKCYE
                     ERLVENTIIC"
     gene            complement(12039..14162)
                     /locus_tag="JAM15_16280"
     CDS             complement(12039..14162)
                     /locus_tag="JAM15_16280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAT6799809.1"
                     /translation="MQNSVKQEPCDFSHGRFRPEADILDSRLTKVLDLFQQLNMCLHK
                     DNFRGSITFFISKSFLGRTEKQIYNVIKRKYEQLCENLDSNIEEKAWLFEELLKDNGK
                     NIHLCKPLESDEREGLLKQVLELDEVKDKTSAFQYPISADARLVLDTLIKEIQNNIVS
                     SLEDYVKAYTEDFISIIGSITMIQEIAKYDEVVKVFKNWLESTTTLTIERFINVLAKQ
                     SGLFLQDSCMELQNKIKGNLDIIDALSKYTEHGTGEILLPSVHMEFIIEKASKKIMEQ
                     NFIIIRKNLEKVLVSYEVQKQVFTLPNREKLMEVANKKDYVYSVSDFNSILTNVTVTQ
                     NEELEDSITRLSAYGEEGNEIIREFIGKYILNPFIVKTININDKKGIEIRALIPNLVI
                     SSVLEYFKNRKVDDNVSTFMFFAKDTIYMDDNLGMDFASEKNIILACNNLDVGSNVKI
                     NVSGKSGELVDSSMYGKNGEDGRDAGNIYLYIKEEIRNYRLTLIANGGNGSKGIDGKN
                     GETGDSGSNGADAGYTSSFHGQMFKGYFAKGTSGKKGDKGGAGGNAGRGGNAGNKGNI
                     YFISDSEEQKNRIINHCDITVKDGEAGPNGRPGSGGYGGSGGYHGYNTLSFSPSGIDK
                     TVYYTGYFTSWDYKLDSIIKYHIEFSGGSWNEGKTGPAREYAEYGDRGDDGGFNAPNT
                     KLSTAVSKVEENLIKEKYQGYCSEI"
BASE COUNT         4683 a         2621 c         1613 g         5419 t
ORIGIN      
        1 gaataggata tttttcctac tcttttttct gtgcttatat ataatattaa agctctttat
       61 tttcaatata tattttaaat tttctctttt taatatatct ttttctttta ataaatctct
      121 ttaattttct tcttctatat cagagccaaa gggaatccat gcattaccaa actctttatc
      181 tttaaataaa taagctaatc cagttatttg cttcaatcta agaatttcat caacttccat
      241 acccaggtgc tttgatatcc attcatcaga ttttccaatt tcacaaagtt cagttataat
      301 tttactcatt aaatccacat tatgagaacc tcttgcacga ttgtgtcgaa tagtacttgc
      361 cattctttca tcaagagatt tatcaattac tgaaacagga agaagtccgt tttctctatc
      421 atatatatcc tcattttcaa gcattactct atatctatga aaaccatcta caataatata
      481 cttatccttt tcctcattat aataacagac aattggcatt gtatacccat cttcttttat
      541 acttttatac aacaactgca tttctggtgg ggctactgca tttggattat agtcgttaga
      601 ttctatcttt tcgattggca ctgcgatgat tccatataca ggacttttat attccatagc
      661 atcttaactc ctatctaatg aattttttca tatttcttct taatatattc cgttctaatt
      721 ctctgttctt ttgtaggacc aaatcccata aatctacaca tatggtcatt ttttaaaata
      781 caataacaca ttcttttcca acttggtata tctttggtaa atttaatatc atccgtatca
      841 tcaggtatat catccaaaaa tatgactcta ctctttttat cttttgtatg atttgaaact
      901 ccatttaatt ctattttata gccttttctc aacaattcac gtataactat ttctgacaaa
      961 ccaccacctg tattctgcca aaactcaata gatgttgaaa attttttaat atagctattc
     1021 cttatatttt caggtaaggt atcaagcaaa aaatatgtga aacttttcca tgtgtgtcca
     1081 tatggcaatt taacactacg atatcccata gcttttgttt tgccataaat agaagtaaaa
     1141 ttaactcctt gtactctagc aaccaatttc acccatacat ctggatccaa tattctgtat
     1201 aaatttaaac tctcttttgc tgaatcatta aaaggtgatg ccactctcat ttttcttgga
     1261 gctactccag ctttatagaa taagtcataa attttattat agtcataatc aaatttatag
     1321 tgggctaacc atatatcttc tatttcccaa tcatatatag gagatgccgt ccagacattt
     1381 ttaaattcct tagttatcca gcactttcct ttatatccat gctgtttatt cacaatagaa
     1441 caataacgtt gtagagattc tgctgctcgt gttcctaata agcaaacaac ttttgcacct
     1501 tcatgtatat ctctaatcca tctaccaaat tgctttgcca aactttcttg tctcatttta
     1561 tacttataat aagtaaaagg attatttttt tgatttatta tgtattcttt gactggcatt
     1621 tctcttaccc ataattcttc tttctcatca tcccatggat accaatacat ttcataattt
     1681 cctacagcag ttcttgtagc cattggtaaa cacacccaat atggttcaat atcttcaata
     1741 ttctcttcaa atactttttc aacatattca gtagtcaaac tatattgagc ctcaaaatct
     1801 tgatgaaata ctcctatttt ggaacttata ttattctttc tcttataatc caaaactaaa
     1861 tttagcagta agccactatc ttttcctcca ctaaaagata catagatata atcaaattca
     1921 ttaaaaagat aagaaagtct ttcttgaaaa gcttcaaata catcggattc taaatatctc
     1981 ttatccattt gaattatccc ctttcaatta gaagtttata aaaccttaca atacaatatt
     2041 attatgcttt tttagcagta atcagcataa attatacatt atttaaatac acaaatccaa
     2101 ctaaacacat ataattataa tgtaattata cttttgtatt ataaactata ttttatcatt
     2161 attttacatt tttttccaat atatataaat atcatatttt tctattagct aaaaataatt
     2221 actttatatt tttacatgtt agtataataa gacataaaaa cttgacatac tgttgtcata
     2281 attactttgc tataattaaa agtaaaaatg gaggtaaatt ataatgtatg aacgtatgct
     2341 tgataaaagc aataaaccct gtttgtctca aataatagaa tatataggta aagatggata
     2401 tgcacgattg tgtaagttgg aaacttactt ggaaactcaa tataatttat caagagaact
     2461 tcgatttcct tttggaaaca attatggttg gggttacaaa tatagccata aatcttttca
     2521 tttattttat gctttttttg aaaaaggtgc atttactgtt ctgattcaga taggtgacaa
     2581 gcaagtccca gcagtagaaa aaacgttggt atctttgaca ccaaaagcta aagaactctg
     2641 ggtcactcgt tatacttgtg gcaataatgg aggttggatt aagtatcgta ttttagaaga
     2701 tgcagactta cttgatatta ttcaatatat aagagcaaaa aaatctccac ctaaacaaaa
     2761 ttaactttta ttttttgtga tttaaatata gtgtatataa attccattct ttccatatta
     2821 aaaaaataat ataaaaaata tctattagta tatcttattt agtatgtctt attctacttt
     2881 ttacagataa ttaaaaagtt ttatcataaa taaatcataa ctaaacatcc tagtaaatca
     2941 aaattcattt attctttttt attagaattt ttgataacag tccctataca tatgccaatt
     3001 atcattccaa aaattagacc ataacacatt gtgataccca catttccttt agaaatacct
     3061 atagcacaac ctatagccat tccaagtatc atgcctataa acatacatat aataactaaa
     3121 ttgttgtttt tattcatagt ttttctccat tcaatatatt ttaaattgcc tagctcgcct
     3181 tcttagctta aaacaaagaa atataaatta actttctttc attctaatat ctgcttgtat
     3241 aaatgtcaaa caacacattt cttgtcataa cctcctcttt ttgaagtaag tacaatctcc
     3301 cagacacaat aatatcaatt tcctaaaacc atttaagtaa cttttatatt tacataatat
     3361 ttacaatcat aaactatatt gttattcatt tatacatcat aaacactccc tcctaatcat
     3421 tattatactt aaaataatgt tcatttataa taatatatct aacgcacttt aattgaaaaa
     3481 actaaaactt tgcctttcat tcccatatat aaataagtat actttttgat gctctattac
     3541 aaatcaacta aattaattga tataaattat cattttctgt tgaaaatacc attcgcacat
     3601 gctatactta attgcataaa tggtaataaa tgtcatatga ttttacaaat ctattaataa
     3661 caattattac ttttactgta ttttaaagtt tttggactaa atatcaagaa ctttctaaaa
     3721 tacaaagtac aaaaaattta tataagttat aaatttatat gaactagata agctcaaaca
     3781 atatgttatg tataaactgt gtagtattcg gttataaatt tatataaatt atataagcta
     3841 tataaagtat tacctcaact atataagcta gataagaatt atttcaacta cacaaactac
     3901 atatgtaaaa ttcatgtaaa tttactaata taaatcaaat aaaattacta aactctctaa
     3961 actaattttg taaaacatac tctattttta acatttgtta ccttatacat aagtataaac
     4021 aaaatctaac taaatgaaag gataatgtaa aatgaatatt ttaaaaatga aaaaaacagg
     4081 aatattttta ggaggagtac tttttggtac tgtaggtgtt aagatacttt caagtgactg
     4141 tgtaaaaaaa acttgcactc gtgcaacagc aggagcattg aaagttaaag attctgttct
     4201 tgaaacaact acgaaaattc aagaaaatgt agaagatatt ttagctgaag caaaagaaat
     4261 caacgagcaa gaagacttat ctacatctaa ggtaaacgtt gtacaagata ctcttaaatg
     4321 cgaacaagaa gttcttaaaa ctgaaactat aaaaactgta gaagatacta attctaataa
     4381 cattaaatgt gaagaaatca aagataacgt aattgaagaa aaaaataata cttgtacaac
     4441 agaataaatt taatgattat tatgattaat aatatcagga ggaagtaaat tgaattttta
     4501 tataaaacac gaaataagag gtcgtatacg ctttgactta caacttggca aattaaacaa
     4561 caagcagtcc gatactctct tatattattt aacttctata aatggtatta ccaaagcaaa
     4621 agtttacgat agaactggtg atgcagtcat ttattacact ggtgaaagag aatacataat
     4681 aagagaaatc actaaattca gttttaacaa tagcaaaata gaaaacctag ttcctgaaca
     4741 taccagcagg gaattaaaca attattatag agacaaatta gcaaataaac tgctagtcaa
     4801 aagtatctcc aaaatatttt ttccaaagtc cttaagattt tttttaattg gacttcattc
     4861 tataaaatat tttaaaaaag gtctctcttc cctactaaat aaaaaaatag aaatttctgt
     4921 tttagatgcc actgctatag gtatttctat ttttagaaaa gatatcaata cggctggttc
     4981 agttatgttt cttcttggta tcggtgagtt attagaagaa tggactagaa aaaaatctat
     5041 agacgacttg gctcaaagta tgtcactaaa cattgaaaaa gtatggttaa aaaaagatgc
     5101 cactgaaata ctagttccaa tttcagagat aaaggaagga gatttagtca gtgtaactat
     5161 gggaaatatg attccattgg atggagttat agtatcagga gaagcaatgg tcaatcaggc
     5221 atcacttaca ggtgaatccc ttgcagttaa caaaaaagaa ggctcttaca tatatgctgg
     5281 aactggaata gagcaaggca atattgttat gtgcgtcaag gaaaaagctg gtactactag
     5341 attccagaaa atagtaacta tgattgaaga atctgaaaaa ctaaaatctt ctgtagagag
     5401 taaatttgaa catctagcag atacattagt tccatacagc tttttaggaa gtatattaac
     5461 ctatgcaatt actagaaacc ctataaaatc actctctata ttgatggtag atttctcttg
     5521 tgcattaaaa ctctctatcc ctatttcagt actatcagcc atgagagaat gtaacaatca
     5581 cagcattgct gtaaaaggtg gaaaattcct tgaaggtgtt gcatgtgcag atactattgt
     5641 atttgataag acaggcacat taacaaaagc tcaaccaact gtttcagata taattacatt
     5701 ccaaaattat aataagaagg atatgttaag acttgcagct tgcttagaag aacacttccc
     5761 acactccata gcaaatgcag tagtttatga agctgaaaaa caagggctta gtcacaaaga
     5821 aatgcataca gaggtagaat atattattgc tcatggcatt tcaacaaagg tcgatgataa
     5881 aaaggttgta ataggtagca aacattttgt atttgaagat gagaagtgta ctatcccaga
     5941 cggtgaggag gataagtaca acaatctatc agatgagtat tctcacctat ttatggcaat
     6001 atcgggtaaa ttatcagcag ttatttgcat aaatgaccct ttacgaaaag aagcaaaata
     6061 tgtaatttca aatttaagag aatatggaat aaaaaagatt gtgatgatga ctggagatag
     6121 cgaaaaaaca gctaaatcta tagcaagtaa agttggtgtt gatgaatatt attcagaagt
     6181 cttaccagaa gacaaagcca attttgttaa aagtgaaaaa ctaaaaggtc gcaaagtaat
     6241 tatgattggt gatggaatca atgattctcc tgctatttca gaatcagatg tcggaattgc
     6301 aatgagtgaa ggtgctgaaa tagcaagaga gatttcagat attaccatat cagcagataa
     6361 tttgaataat ttaatcgttt taaagcagat tagtaataag cttatgaaaa gagttgattt
     6421 aagttctaag tttattatcg gctttaattt aggtctgatt ttacttggcg taagtggatt
     6481 tgttagacca agtacatctg cctttttaca caacgcatct actgttggaa taagtttaaa
     6541 cagtatgaca aatttattgg aaaacaccaa tacttataac tactattaat ccccattata
     6601 taaaacatat gtatataaaa aatttataat tcatctttta aaaagaaact gtcttaaaag
     6661 gagctttttt ctaatcaaaa ttatataaaa catattttac aaattttaaa ctcaacttat
     6721 ttctattttt tacaaaaagg agatgattca aattttcatt ttgaaacatc cccttttgta
     6781 aatttcttta aaacttatat attaattata ttttcaacaa ataattgtat tttcaaccaa
     6841 tctttcttca tagcatttta aatcattttg ctttagataa ttaaattcag actctacata
     6901 aataccacag cctaccaatt caattgtcaa attaggtata ttttccttta gtatactagt
     6961 ctgctcataa ataattcttt ccaataaatc aacttgtaat atagaaaaat gcttcataat
     7021 ctccccatca ctatctatat ctttcttgat ttcataccaa ctctttgaca aaattccctt
     7081 caaatcaata taccctagac tcttcaatat atctatactc tcgctccatg catacttact
     7141 aggtttatca aagtatgatt ctagtttctt cttctgctca tttgtaagtg aatcataaga
     7201 aagcttctta ttaaaatgtg ccttcaaaga aatcttagcc atagaatatg gacttctacc
     7261 agagtttaat cctgcatttt tgaacttttc aattccttta tcttctactg aagaccatat
     7321 tgagtttatt gaatctgaat cattgtattt aacatcaaga ccatgtgtaa tatctatata
     7381 gttttgtgga aatacatatt gataatagac atctttttta tcatcatata gggagaagta
     7441 tccactatca tataaatgaa tatgcacctt tacttttaaa ctatcctcta aaatatttcg
     7501 tctaaggttc gggatatttg catacatggt tacatatttt atggcatcaa agttttgatt
     7561 taatggaact tcaaaactaa tttcatctcc tgtcaaaagc tttttcactt cttcttcatt
     7621 acaatcatat agagaatatg tattttcaaa tcccacacgt gatttcccat ctaaacttcc
     7681 tgttaatgct accttcaaaa tatggttatc cgttttttgc cattggtaag catcttggtc
     7741 aagaaactct ctaatctgtc tattttgctc tttcgcctga tttataacct cgttttcatc
     7801 ttctgtaatc cctacatggc atctatttaa tatatttact atattgcttc caaatgggaa
     7861 tgtccatagt tgaaaagctg ctgcctcaac ctgacacaaa tatctaacct gatttaattc
     7921 aatttgatgg ataagttttt tctgatattc attcatctga ttaccactac ctgacatttg
     7981 ataaatcaat tctcccattg caagattatc ttttttctta tcaatcttat cagtaatgat
     8041 aatttgagtt tccatcatat cctgtacttt tttaaatatt atagaaatat cctctgaatt
     8101 ttccattttt aagctttcaa actttgtgct taattcagtt aaaacttcct tcatctttaa
     8161 tttacttatc tcattttcaa aaatatcttg atttttaact gtactatcaa atttttctac
     8221 aaatggtata acagattctt tcaaagtttt atctttaaat tccaccattt gagtattcaa
     8281 ttcatctaat ttcttaatat tattttcttt atccttaatt gcctctttaa ctacctctat
     8341 tttactctca aaactagatt ttacattaag acaattatta acaccactaa tcgcagtatt
     8401 tataagagaa caagcagaac ttccaatact caatgcgttt ttaattttag atgtcttttg
     8461 ctgtctttca atagcttgtt tacttttctc tagtgcagct aacttatctt tttgctgttt
     8521 attattgtaa tttgcctcca acatacctat ttcttttttc tggatttttg tgtaaatttc
     8581 cttatactcg ctttcactta acccctcttt tgctctttga atatcgtcag ctttgtctgc
     8641 atagttatca tcatctatag acttaactat aatctcctta atttggtcaa atttagttct
     8701 tctttcttca tcaacacctg ccaaattata agtcatttta tctaaagcat tttttctatc
     8761 ttcacttagc tgttctccaa gtacaaatct cataccatca gaatccaatt taaaatctga
     8821 aaaatcaacc atcctgttag tccatttgta ttcctcttct ttagctgaaa gattttcctt
     8881 caaagatttt gcactgtcaa atgcccctag acaagcttga ccaacaccac taaatgcagt
     8941 cagtaaactc aatgcgcttt gtattccaga aagaattaac tgtgttttca tttgttcctc
     9001 aagttttgcc tgtttctttt ttagttcctc tatgtcttct tgttcatctt ctttcatctt
     9061 tataatttct tgaatcaaca ggttcatctt tgcattaaca gaaagcattt tattctcaag
     9121 ttcatttttt aaaacctcta tttgttgatt tccagattca atttgagtta ggatactttc
     9181 cttataagta ttgaaatatc cttcttttaa ctcatctttc tttccttgtt ccaattctct
     9241 taaggtcttg tccagataat ctgtcaaaga acgaatatct gtaacacgat ttcctccaat
     9301 ttcactttct tcaatcatct gcacataaaa tgctgttttt tgttcaagtg caaataaaat
     9361 catactccat tcgctaaaat tcttcttttc tcctataaaa gattctattc tatcagactg
     9421 catcaattta tttataaggt attcatagat ttcctttgcc tccttataaa attctttctt
     9481 tatattcata tcatccagag aaagcactgc tttatttttc ttctcaaaac tatagtactt
     9541 ctgaagtatt tctctattta attgcatctc tattttctca actgcatgaa aaatttcata
     9601 aatatgtgaa agttctaaaa tatcagcttc taaaattcct actgcacaca acagtctaag
     9661 atttctataa cctttaattc cagaaaaacc aaatctctcg aaaaattcat agaagaaggt
     9721 atctattgac aaagaatact cctgctttaa caattccttt tcttttaatg catctccaga
     9781 gcgaccatct tttccctctg ctccgactaa acctgaatct tcacgtttgc taattgtcca
     9841 gtccttatgt ttttcataaa gagcatttaa tttctctcca tcatccgcta cttggttctc
     9901 atttgaagca tgattaaaca catatctatc aaaataatag taatttctat cactgtcatc
     9961 tattggagca gaggtaccta tatatcttat tgtttcttca tatatacctc taattccacc
    10021 aagacctcct gcaccaccag ctcctccaga gcctcctttt cctgctagac catgatttcc
    10081 atctttttta cttatagcac cttttaataa agaagctttt ccaaggagat aaacctgtcc
    10141 agacttgctc ccaagacctg catttccacc attacctcct gtgcctccag ttccaccttg
    10201 ttttcctttt tctgctttta ccacatagta ttttgtacct ttaacattag caaattcttt
    10261 tgactctttt ttagaaccta ttttagcatt ttccccagct tctccagtta tccctgtatc
    10321 tcctcttttt ccatcttgtc catttccacc acgtccacca tctacgtaaa gtttaagttc
    10381 tcctcttttt tctatttctt taaaagataa taaaatatca cctgaagtac ctgcattatt
    10441 gccatttctt ccattcattc cgtcgtaaat agaaccttct ccaaccaatt tttctgcatc
    10501 cttaccagat acgttgattg aataaatccc ttctggtata cataattttt ctgtaagtag
    10561 tacaatattc ttacctgaga agacttcttt ctccatatta cagtcaattt tcaactcaca
    10621 atctccatac atatatatag atgacaaaat attaagttga taaccagata ttattttagt
    10681 caaatccgat aaattcactt taggtatagg aatatatata gaaagtacat tttctttctc
    10741 atatgatttt atatatgtac aactttgaat cttctctatc ctatactctg catcttcaag
    10801 ctttttggct tcttcttccc tatattcttc ttctgctatc caatatttga tatcttttaa
    10861 tgtatcttct aaagtatttt ttagcaatga ttttaacaac tcacttagac caacaatatg
    10921 agtctcacta cagtagctat ttaactctaa aagaagacgt gtttcttcta atatattcac
    10981 tttctgtacg ccatcaccat atgaaagttc ttgtacaaac tccataagct ctttcatatt
    11041 attagtccta ctacataaat ctgtatacat cttatctaat tgagtctttt tatcctttag
    11101 actatttata gaagatagaa tggaaataga atcttccata ccttttttga cactttctat
    11161 ataaggaact aaaagttttt ctaggtcttt ataggttaca tcaacggctt tttgtatttc
    11221 tattttacaa gaagcagtaa gcatcaatcc caaatctgtt ttttcaaatg tttcaggtag
    11281 atttttcatt tcatccaaca acttttctgg ctgtttatct agtggattac ataatttaat
    11341 agatacacca tctgataatg ctacatttaa taagtacact aattccttac aaccgtcgta
    11401 atctttctct tgactatcca ggtcttcttt tgctttttcc aatatattcc ttattttttc
    11461 ttctgttaca ttaccgatta gtgttttagg tattttattg ataagaaaga agaaattttc
    11521 tttatacttt gcataatcac caagcatatc tttcaaattt ttgcctgttt ctatcaataa
    11581 tgtatgtcta gagtccagta aggattgata gtctaaaata actaccatcc ctttcacctt
    11641 tgaagatgta gaaatagttt cccttacaag catagcacca gcaatcatat actctgctcc
    11701 acggttatca aaaaaacctg ggcaatcaca taatgaaaaa tttctatttg caatatctac
    11761 aacttctgga cataaagtct tagaatatac accatttcca atttcgacag ctgaatcttt
    11821 tgcagttata tatatttgtc cagtctcttc atccgttttt tcttccatca cgcaaccttt
    11881 taaataattt atacaggtac tctttccaac gcctgaagca cctaagaata acaaaattga
    11941 cttttctttt aagtcatatt ttctaagctc gtctcttcct tcttccaaaa ggtttacgat
    12001 ttcactataa agtttatttg ccatacatcc atccctttct atatttcgga acaatagcct
    12061 tgatattttt ctttaataag attctcttct acctttgaaa cagctgttga taacttagta
    12121 tttggagcat taaatcctcc gtcgtctcct ctatctccat attcagcgta ttctcttgct
    12181 ggtcctgttt tgccttcatt ccaacttccg ccactaaatt ctatatgata tttaattata
    12241 ctatctaact tataatccca acttgtaaaa tatcctgtat agtacacagt cttatctata
    12301 ccacttggag aaaatgaaag tgtattatat ccgtgatagc caccacttcc tccatatcca
    12361 cctgaacctg gtctaccatt tggacctgct tctccatctt tcactgttat atcacaatga
    12421 ttaattattc tatttttttg ttcctctgag tctgaaatga agtaaatatt acctttatta
    12481 ccagcatttc cacctcttcc ggcatttcca ccagctccac ctttgtcacc ttttttacca
    12541 cttgtacctt ttgcaaaata ccctttaaac atctgtccat ggaaactact tgtatatcct
    12601 gcatcagctc cattacttcc agaatctcct gtttcaccat ttttcccatc tattccttta
    12661 gaaccatttc ctccatttgc aatcagtgtt aaacgataat ttctaatttc ttctttaata
    12721 tataagtaaa tattacctgc atctctacca tcttcaccat ttttcccata catagaacta
    12781 tctacaagtt ctccgctctt tccacttaca ttaattttta cattactacc tacatcaaga
    12841 ttgttacaag caagaataat atttttctct gatgcaaagt ccattccaag gttatcatcc
    12901 atataaatag tatctttggc aaagaacata aatgtagaaa cattgtcatc tacttttcta
    12961 tttttgaaat attccaatac actactaatt actaagtttg gaattaatgc tcttatttca
    13021 atacctttct tatcattaat attaattgtt tttactataa atggatttaa aatgtattta
    13081 ccaataaatt ctctaattat ctcattacct tcttctccat atgcacttaa tcttgttata
    13141 ctgtcttcta actcttcatt ttgtgtaact gtaacatttg tcaaaattga attaaaatca
    13201 cttacactat atacataatc ctttttattt gcaacttcca ttaatttttc tctatttggt
    13261 aatgtaaata cctgtttttg tacttcataa gaaactaaaa ctttttctaa attctttctt
    13321 attataatga agttttgttc cattatcttc ttacttgcct tttctataat aaattccata
    13381 tgtacagaag gtaataaaat ttccccagtt ccatgttctg tatatttact taaagcatca
    13441 attatatcta agtttccttt tatcttattt tgtaattcca tgcaactatc ttgtaagaat
    13501 aagccacttt gtttggctaa tacgttgata aatctctcta tagtaagagt tgttgtactt
    13561 tccaaccagt ttttaaatac ttttacaacc tcatcatatt ttgctatttc ttgaatcatt
    13621 gttatacttc caataatact gataaaatct tctgtatacg ccttaacata atcttctagg
    13681 ctagatacga tattgttttg aatttctttt atcaacgtat ctaaaactaa tcttgcatct
    13741 gcactaattg gatattggaa tgctgatgtc ttatctttaa cttcatctaa ttctagtact
    13801 tgctttaata agccttccct ctcgtctgat tcaagtggct tacaaagatg aatattttta
    13861 ccattatctt ttagcaattc ttcaaataac caagcttttt cctctatatt actatctaaa
    13921 ttttcacata attgttcata ttttcttttt ataacattat atatttgttt ttctgttctt
    13981 cctaagaaac tttttgaaat gaaaaaagtt atactgcccc taaaattgtc tttatgaaga
    14041 cacatattta actgttgaaa caggtctagt acttttgtaa gtctagaatc taatatatct
    14101 gcttctggtc tgaacctccc atgactaaag tcacagggtt cctgcttcac agaattttgc
    14161 atactaaaat atgtcttact aattctccac aggccatccc cgtagttcct acggttctta
    14221 cataagttat ttattttgaa ttgttgttag tcttaatcct tcttttaata tatttatgct
    14281 tgcatttata tctctttgta atttagcaag tttgtttaat gacttcttaa gatact
//
LOCUS       DACTZW010000100        14094 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.100, whole genome shotgun sequence.
ACCESSION   DACTZW010000100 DACTZW010000000
VERSION     DACTZW010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14094
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.100"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            167..1060
                     /locus_tag="JAM15_16285"
     CDS             167..1060
                     /locus_tag="JAM15_16285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAT6799810.1"
                     /translation="MQLYNTPFNTNKHLIYFFTSTLVLNWIFSLTPALLGITNTILGE
                     IIFYLAYTSPAIVGLFFISTIYPQSAKQDFIYRYLSFKEIGIKWILLTILFFALTFIT
                     SLIIGNYFNVKTSDIDWIHIAVFRPSKIAYMLLASFILSILSQEAGWRGYAIDKLLVR
                     FGFIGSSIILGLVCGIWYLGSYFTPNQIPYNLAQYSLFDAFLFIPNIVLLNFIINYIY
                     INTSRSILSAGLVHMMYYFFNIQLLLHYPIKLCVIAQYVQIIFGLIFLVYMISSNKFK
                     QKVNSEIEQIKSDDFEFELDW"
     gene            1238..2062
                     /locus_tag="JAM15_16290"
     CDS             1238..2062
                     /locus_tag="JAM15_16290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAT6799811.1"
                     /translation="MFKIGEVSKLTQISIRMLRYYDELGILKPAEIDKYTGHRLYSVE
                     QISILQRIVLLRDSKFSVAEIANIVHNWNDEFVIKELNRKKNEIQKEIKHEQQRINKI
                     DKFIEAINCDKDEIHYNVVFKKIPSYKIISLREVVPDYQSEGILWEKLSKFIKEEHIE
                     VSRQPNNNIAFYHDEEVKDNGVDIEVGMVVKKIGKNKSGFIYRETEEIDMMACTMVYG
                     PYENIAGAYESFCYWLDKNSDYQISGINRQIGHKGEHNEINPENYLTEIQIPLIKV"
     gene            2188..2769
                     /locus_tag="JAM15_16295"
     CDS             2188..2769
                     /locus_tag="JAM15_16295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAT6799812.1"
                     /translation="MKADSTKEQLINATIQLLSSHRDVSSITAREIVAKANVNLAMIN
                     YYFKSKEELINISIKKFLKRHMDEYKATHDTKNLAPKQQLREILIAFFDFIGEHSQFI
                     KISVPYILIQEEIVYPFEILPLIKAHYENQNNKKTEAEYRTIAYQITSFIQLLFLRSN
                     AFFKYSGIDILNVEQRNGLIDFQLDLLLVDITK"
     gene            4345..5097
                     /locus_tag="JAM15_16300"
     CDS             4345..5097
                     /locus_tag="JAM15_16300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6799813.1"
                     /translation="MLKVNQLCKSYKTGNKTYPVLKNISFEINKGEFVAIMGSSGSGK
                     TTLLNCISCFIPIDNGEIILGNNNIRNLKEKELSEVRNQQLGFVFQDFMLFDGLSVFE
                     NICVPQIIKGSQVLQMENRAINLCELFGIEHIRKKYPAEISGGEKQRTAVARALMNNP
                     DLILADEPTGNLDSKSCRTVIESFLKAKQELDATILMVTHDSFAASFCDRVIVLKDGI
                     IYKEVVKSNSRHKFLDELLEVLKEMGGAQDDN"
     gene            5087..7198
                     /locus_tag="JAM15_16305"
     CDS             5087..7198
                     /locus_tag="JAM15_16305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAT6799814.1"
                     /translation="MTINKLYSKLRAYNWKNYTTLFFCIILSVVLVTSYALIYFSPTI
                     QNILPTGGDSRKQATMIFSVAILGCAVFTTYASSLFLKFKSKEIGIFMALGTDKKKLK
                     KLLFSEILLISIVCCFLGLILSIPVSFGIWKIFQLVIIDTREMTYHFGTQGFIYGFIF
                     SVFVTLCIFILSVKFINRTNIIDILNDQRISEPIQDVKDWYGILGIIFIILGIFLGYI
                     VPSLTINKLNYRLPSVWSFTYLLSLIGIYMIMTYIVVHAKRGKHPEKYYKNIISTSMM
                     RFMGRQTVKNMCVISFLIAGALFAVFYVPNMVAGIYDTLKNNPIDYTFTYNQRDKQVS
                     KKDIEQLADKHNIKIQNYMEIPSIELIVDGVESIYHKDGTIERVYMKKSSYDMFFNSK
                     DFSKLIDKPITIKNGEYLAVVNKGNENQDYKYTKFISSPVTEKEIPFRYAGKIIFNGS
                     FFQNRSMNAYVLNDEDYKSFTKDLSIKNYNNSILFNVDKDTYAFANDLKKEIIKRTSK
                     EMGMFRGYDEYVKKRYESTGRKYFMDEEYPSGEGHLKLDPNNNQLYLNWKYYPNFKIL
                     QSQDMIKNMAVFLMLFIYVAIICFTAVGIIAYTRGVTIAINHKQVFMDLNRLGANNDY
                     IKFCIRNQLKKVFSYPLIAGSFLIYLFNFMIMLNNDGRIVNSEVNALLINLGFIGICG
                     VYMYLIYLLTYKKFKKIIGIL"
     gene            7813..8523
                     /locus_tag="JAM15_16310"
     CDS             7813..8523
                     /locus_tag="JAM15_16310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6799815.1"
                     /translation="MTSICICDDEKQQRNMLNKIITREMDLWGYPYQIKEYSNGESLV
                     YNLEHENYYIDIIFLDIELGKSNGVDIAKTIRKHSKDTIIIFVTGFSDYVFHGYDVGA
                     LNYILKPYKTEKICKVLKEALKKLEQWKENFITVQIGTNLCKINTKDILYFKSELRKL
                     TVVTFDKTLEYYGKLNDMETVLPSNFIRTHQRYIVNLNHVDSITQTYAKVQNEKIPIS
                     RKKYQEVVGKFTRYMLEP"
     gene            8963..10300
                     /locus_tag="JAM15_16315"
     CDS             8963..10300
                     /locus_tag="JAM15_16315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAT6799816.1"
                     /translation="MDTYSLISTSINFILILINIFIAFFLYKLTSYFIDFRNHWIFKI
                     ILILGYSIISQMIIWLSDPVNILFTLFGYFILLIICSKSKLIPIISVVMILYPIIIGL
                     NFLFINNPIYEELIHSKEYILILSIVQIISALIKLLFWFLIHIFLKNRLVNIKQYLSN
                     KIWIFIDMVCISSFLSILIAIILPPTNLIPMGSNKNIILGNLPYGTYLIILSAILANI
                     GVILLLQPLIENVKMKIEKQANHLKEKYYNLLENQQIQIRKMRHDMNNHFQMIESYLE
                     IEDIAGAKKYFNQLKIGIGTLSGKQFCKNQALNSILNLRHTSLEENGVDVHFNIDIDN
                     HLGIEPIDLCTIFSNSLDNAIEASLKIPDLSNRKVVLKARCEKEYFSYLLTNNKVNPI
                     NRKQELFISDKKDSNSHGYGIENIREIVNKYNGKLDISYTENEFSLFLYIRLF"
     gene            complement(10637..11206)
                     /locus_tag="JAM15_16320"
     CDS             complement(10637..11206)
                     /locus_tag="JAM15_16320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HAT6799817.1"
                     /translation="MKKKLEDMTLEELWNLFPIFLTTHKECWKNWFKEEQYRLTGILP
                     MQKIVRISHIGSTSVSTIYAKPIVDILIEIIPDYNMKDIKDLIESNGYICMSESSSRL
                     SLNKGYTVDGFEERVFHLHIRYVGDNDELFFRDYLIDHPDVAKEYEKLKLDLWKKYEH
                     NRDAYTDSKLDFVREFTEKAKVLYSNRYN"
     gene            complement(11562..12575)
                     /locus_tag="JAM15_16325"
     CDS             complement(11562..12575)
                     /locus_tag="JAM15_16325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HAT6799818.1"
                     /translation="MVSSFLNDIFRTILVSCIFIVILLVFRITLFKTFSKKFNYYIWL
                     IVIIKLSLPFMNYTFIFNESKYNGNINKISLGNFNSISIVYSTVLVSVWIAITIFYLV
                     YTLLKYIKLKNMINDLSYDVEDDKIKNLYENLLKELKINKKIRLKYSYEVESPVFFNS
                     CVILPPCDYTLKELNWIFRHELMHFKSKDLYIKYLVIFLKCVYWFNPFVYIMEKFIDL
                     DCEFYCDERVLKNCTIEEKQDYALTIISAMRKGSNSSNKFVAGLHKESDIKKRVFSMF
                     NEKYRNGILIAVILCLLSSITYFEIDLITTKSIFYPLSKQTPIENRTNSKPTYQINVY
                     IDN"
     gene            complement(13184..14086)
                     /locus_tag="JAM15_16330"
     CDS             complement(13184..14086)
                     /locus_tag="JAM15_16330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HAT6799819.1"
                     /translation="MLPQDYYGLIVILGVILGVMGAFYNWFTLYVQSLYKKIPKIATF
                     GKLLIPFIMAGILGIVMPDVLGSGHNLVEELTSHEYIFGMVVLIFVIRFIFSAVSFGS
                     GAPGGIFFPLLVLGAFIGGIFGMVGVKVFGMNPDYVNNFVLLAMAGYFTAIVRAPLTG
                     IILIFEMTGSVSQMLSLSVISIVAYIVATLMKSKPIYESLLERLLEKNGEPVHKERGE
                     KILDQFSVMFGSPVANKAIQDVQWPENCLLVAIQRGGEEIIPRGKTILRPSDIIVTMT
                     DERDSGAVYDKMENLCKEHTAHIF"
BASE COUNT         5253 a         1969 c         1680 g         5192 t
ORIGIN      
        1 atactaatta attatattta gtgtaaaaat aattaatcaa aatataaaaa ataggatatt
       61 attataggca ataactaaca tcaagcgata acttaataca tataaaaata aataaacaat
      121 taataaaaat taaaacttca ttataaaacg gaaggatagt gaaaaaatgc aactatataa
      181 cacccccttt aatacaaaca aacacttaat ctatttcttt acatctacgc tagtattgaa
      241 ctggatattc agtcttacac ctgcgttact cggaattaca aatacaatac ttggagaaat
      301 cattttttat cttgcatata catcaccagc tattgtaggt ctatttttta tttctacaat
      361 ctatccacaa agtgcaaaac aagattttat ttatagatac ctaagcttta aagaaatcgg
      421 aataaaatgg atattattaa caatattatt ttttgcttta acttttatta cttcgttaat
      481 aatcggaaat tactttaatg taaaaacttc tgatatagat tggatacaca tagcagtgtt
      541 tagaccttct aaaatagctt atatgctatt agcaagtttt atattgagta tacttagtca
      601 agaagctgga tggagaggat acgccattga caaattatta gttagatttg gatttatagg
      661 ctcttcaatt attttagggc ttgtttgtgg aatctggtat ctagggtcgt attttacacc
      721 taatcaaata ccatataatt tggcacaata ctccctattt gatgcttttt tatttatacc
      781 aaacattgta cttttaaact ttataattaa ttatatatat atcaatacaa gtagaagcat
      841 tttatcagct ggattagttc atatgatgta ctattttttc aacattcaat tacttctaca
      901 ctaccctatt aaattatgtg taatagctca atatgtacaa ataatatttg gtttaatatt
      961 tcttgtatat atgatttctt ctaataaatt taaacagaag gtaaattctg aaattgaaca
     1021 gataaagtcg gatgattttg aatttgagtt agactggtaa ttttaatatg aattataaat
     1081 taagataatc tatgatttga tacgattact acttaaatat aatttactct ctataattta
     1141 ttgcaacatc tggaaaataa ttgtatttcc acaatcgctt gaagtatata aaaacaaaat
     1201 atatactaat tataagtgaa aaggaggtca tattttcatg tttaaaatag gagaggtttc
     1261 aaaactaaca caaatttcta ttcgtatgtt gcgttattat gatgaacttg gtattttaaa
     1321 gcctgcagaa atagacaaat atacaggtca tagattatac tcagttgaac agatttcaat
     1381 attacaaaga attgtattat tgagagattc aaaatttagc gttgcagaaa tagcaaatat
     1441 cgtacataat tggaatgatg aatttgtaat taaagaattg aatagaaaaa agaatgaaat
     1501 acaaaaggaa ataaagcacg aacaacaaag aataaataaa attgataaat ttatagaagc
     1561 tataaactgt gataaagatg aaattcatta caatgttgtc tttaaaaaga ttccaagtta
     1621 taaaatcata tcacttagag aggtagtccc agactaccaa tctgaaggta tactctggga
     1681 aaagttatct aaatttatta aagaagaaca tatagaagta tcacgtcaac ccaacaataa
     1741 tatagctttt taccatgatg aagaagtcaa agataatggt gtagatattg aagttggaat
     1801 ggttgtaaag aagattggaa agaacaaatc tggatttata tatcgtgaga cagaagaaat
     1861 tgatatgatg gcatgtacta tggtttatgg tccatatgaa aatatagctg gtgcatatga
     1921 atcgttctgt tattggttag ataaaaatag tgattatcaa atatcaggta taaatagaca
     1981 aatcggtcat aagggtgagc ataatgaaat aaatcctgaa aattatctta cagaaattca
     2041 aatccccctt ataaaagtct aatcgattag tacttaaata cttaagtact aatcacccat
     2101 tgacatccca aaattttcat gatagtatct aaacgtgtat taaacatgtt taattttttt
     2161 atggaaaaac ttttaagggg aaaaattatg aaagcagatt caacaaagga acaattaatt
     2221 aatgccacaa tccagttact atcttcacat agagatgttt caagcattac ggctagagaa
     2281 attgtagcta aagcaaatgt caatttagct atgattaatt attattttaa atctaaagag
     2341 gagttaatta atatttctat taaaaaattt ttaaagcgtc atatggatga atataaggct
     2401 acacatgata ctaaaaattt agcacctaaa cagcaattaa gggaaatact aattgcattt
     2461 tttgatttta taggtgaaca tagccaattt ataaagattt ctgtacccta tatattgata
     2521 caagaagaaa ttgtttatcc atttgagata ctacctttaa ttaaggctca ctatgaaaat
     2581 cagaataaca aaaaaactga agctgaatac agaactattg cgtatcaaat aacttcattt
     2641 attcagttgc tttttcttcg ttctaatgct tttttcaagt atagtggtat tgatattctt
     2701 aatgttgaac agagaaatgg tttaatagat tttcaattag atttattatt ggtagatatt
     2761 acaaaataat actatattaa ttttttatgt acattttttt attttatggt aacgtttgaa
     2821 aatattctca ttgactaaaa atacttgcat taaataaggg ggaggaattt taatgttttt
     2881 tacatttata ggagtaatat cagcaatttt attgttgtgt acaattatat gtggtttatg
     2941 gataaaactt aataatcgta ataatgactc taattctcac tttacttttt caatactttc
     3001 aattgctttt tcactgttaa ttgtggtggc ctttttagta agaaattaat gtctttgtta
     3061 tgctggggtt tattattata gatttttatt attgcatgat ttttactata ttatagtatt
     3121 tttattatat tacagggtct tatttattat agtgttttgt tattacagca ttttattata
     3181 ttacagagtc ctatttatta taggattttt attatattgt aaaatcttat ttattatagg
     3241 attttgttat attacagact tttgttatat tacaatctct tatttattgc agtgttttgt
     3301 tattacagta tttctattat attgcaaact cttatttatt atggtgtttt gttattgcaa
     3361 catttctatt atattataaa gtcttattta ttacagttct ttgttatact acagactttt
     3421 attattacag catttatatt acaatctctt atttattaca gttctttgct atactacaga
     3481 cctttattat tgcaacattt ctattacatt gcaaagtctt atttattaca gttctttatt
     3541 atactacaga cttttattat tacaacattt ctattatatt acaatctctt atttattaca
     3601 gttctttatt atactacaga cttttattat tacagcattt ctattacatt gcaaagtctt
     3661 atttattaca gttctttatt atactacaaa cctttattat tacaacattt tattatttta
     3721 acgtctttac tataatatag taatatttta atatctcaaa atcatatcaa tcacttttca
     3781 gcatagtcta aaatacttcc actttctaaa attatctatc atacctatac taataatact
     3841 ttttaacctt tttattatac atttcaattg tttttaacga cctatttatt tccaaaactc
     3901 caatatattt tctcaattac attgtgttaa taacccctaa atcctttcaa attatttaca
     3961 atacattcca ttaaataatc ttactgctct ataattcttt ttttcttttt aaccctacta
     4021 tacattattt acatcatttt tttcaataca acattcgtta ttctataacc tttttacttt
     4081 tactatatac cttttttcta actacacctt caatgttcca catcatatta ctttagcaca
     4141 acaattaata cctaaaaata accctctaaa tcctccaata atataatcaa tttaactata
     4201 ataataacct ctcacactat ccaaacaata tattttcaaa cattacaaaa aaacatccaa
     4261 ctattacaat attgctcata tccctcctcc cctttcaaat gctatcattg acctacaaga
     4321 taaatgaaag tgaggatgat atatatgctt aaagtaaacc aattatgtaa atcatataaa
     4381 acaggcaata aaacatatcc tgtattaaaa aatatttctt ttgaaatcaa caaaggagag
     4441 tttgtcgcaa tcatgggttc atcaggaagt ggaaaaacta ctcttttaaa ttgtatttca
     4501 tgttttatcc caattgataa tggggaaata attcttggaa ataataatat aagaaattta
     4561 aaagaaaagg aactttcaga agttagaaac caacaactag gatttgtatt ccaagatttc
     4621 atgctatttg atggtcttag tgtctttgaa aatatatgtg ttccacaaat tatcaaaggt
     4681 agtcaagtct tacaaatgga aaaccgtgca attaatctat gcgagctatt tggtattgaa
     4741 catatcagaa aaaaataccc tgccgaaata tctggtggag aaaaacagcg tacagcagta
     4801 gcaagagcac tcatgaacaa cccagattta atattagcag atgaaccaac tggtaacctt
     4861 gatagtaagt cttgtcgtac agtcattgaa tcatttttaa aagcaaagca agaattagat
     4921 gctactatac tcatggttac acacgatagc tttgcagcaa gcttctgcga ccgagttatt
     4981 gtgcttaaag atggaataat ttataaagaa gttgtaaaat caaattcaag acataaattc
     5041 ctagatgaat tactagaagt tttaaaagaa atgggaggcg ctcaagatga caattaataa
     5101 attatacagc aaacttcgag cctataattg gaagaactat acaactttat tcttttgtat
     5161 aatactttct gtggtattag taacttcata tgctctaatt tattttagcc caacaataca
     5221 aaacatactt ccaactggtg gagatagcag aaaacaggct acaatgatat tctcagttgc
     5281 tatattagga tgcgctgtct ttactacata cgcttcttcc ctctttttaa aatttaaaag
     5341 caaggaaatt ggtattttca tggctctagg aacagataag aagaaattaa aaaaacttct
     5401 attttcagag atattgttaa tttcaatagt atgctgtttt ttaggtctta tattaagtat
     5461 tcctgtatct tttggtatat ggaaaatatt tcaattagtg attattgata ccagagaaat
     5521 gacatatcat tttggaactc aaggattcat atatggattt atatttagtg tatttgtgac
     5581 attatgcata tttatacttt ctgtaaaatt tattaatcgt acaaatataa ttgatatatt
     5641 aaatgaccag agaatatctg aaccaataca ggatgtaaag gactggtatg gtatattagg
     5701 tataattttt attatactag gtatttttct aggatatatc gtaccttcac taactataaa
     5761 caaattaaat tatagactac catctgtatg gagctttact tatctactct ctcttattgg
     5821 aatatatatg attatgacat acatagttgt acatgctaaa agaggaaaac atccagaaaa
     5881 atactataaa aacatcatat caactagcat gatgagattt atgggaagac aaacagtaaa
     5941 aaacatgtgt gttatttcat ttttgattgc aggagcatta tttgctgtat tctatgttcc
     6001 taatatggtt gcaggtatct atgatactct taaaaataac cctatagatt atacttttac
     6061 ctacaatcaa agagataaac aggtatcaaa aaaagatatt gaacaattag cagataaaca
     6121 caatataaaa attcaaaact atatggaaat tccttctata gaattaattg ttgatggtgt
     6181 agaatcaata tatcataaag atggaactat cgaaagggta tatatgaaaa aaagctccta
     6241 tgatatgttc tttaattcta aagatttttc caagctaatt gacaaaccaa taactataaa
     6301 aaatggtgaa tatcttgctg ttgtaaataa aggaaatgaa aatcaagatt ataaatatac
     6361 caaatttata tcaagcccag tcacagaaaa agaaatcccc tttagatatg ctggaaaaat
     6421 aatatttaat ggttcttttt ttcaaaatag aagtatgaac gcctatgtcc ttaatgatga
     6481 ggattataaa tcatttacta aagatttatc cataaaaaat tacaataatt ctatactatt
     6541 taatgtagat aaagatacct atgcttttgc caatgactta aagaaagaaa ttataaaaag
     6601 aacatctaag gaaatgggca tgttcagggg ttatgatgaa tacgtaaaaa aacgttatga
     6661 atcaactgga agaaaatatt ttatggatga agaatatcca agtggtgaag gtcatttaaa
     6721 actagaccca aacaacaatc agttgtatct taattggaaa tactatccta actttaaaat
     6781 tttacaaagc caagatatga taaaaaacat ggcagtcttc ttaatgttat tcatatatgt
     6841 ggcaatcata tgttttacag cagtaggaat cattgcatat acaaggggtg ttactatagc
     6901 tataaatcac aagcaggtct ttatggattt aaatcgatta ggagcaaaca atgattatat
     6961 aaagttctgt attagaaatc aattaaagaa agtattttca taccctctta ttgcaggaag
     7021 ttttttaatt tatctgttta attttatgat tatgttaaat aatgatggta gaatcgtcaa
     7081 tagtgaggtc aatgctcttt tgataaactt aggttttata gggatttgtg gagtttatat
     7141 gtaccttata tatctattaa cttataagaa attcaaaaaa attattggta ttttataatt
     7201 aaggaaggtt gttagatttt taaagtaata aaatcattac tttttataat aagaaaagca
     7261 ttagcatttt aaattaaaaa aggttattag atttttatga tatgaaaagt cattgtattt
     7321 ttatagtaag ataattattt gctttttata atatgaaaat ccattatatt tttatagtaa
     7381 gataattatt tgctttttat aatatgaaaa gtcattgtat ttttatagta agataattat
     7441 ttgcttttta tagtattaaa agtcattgca tttttatagt aagataatta tttgcttttt
     7501 atagtattaa aagtcattat atttttatag taagataatc atttgctttt tataatatga
     7561 aaagtcatta catttttata ataataaaag cattggtatt ttataataag aaaggttatt
     7621 agatttttta ataagaaaat cattagcact tcagaataag tttaatagaa tagttttaag
     7681 tgtaagtata ctaatataaa aaattttatt ttgctatctg gatataattg ttatttcatt
     7741 ttatatatct aggtagcaaa atatattata tacttaacta tataaatata aaacttgaaa
     7801 ggagataaaa aattgacttc gatttgtatt tgtgatgatg aaaaacaaca aagaaacatg
     7861 ctgaataaaa tcattacaag agaaatggat ttgtggggct acccctacca aataaaagaa
     7921 tattcaaatg gagaaagtct agtatacaat ctagaacacg aaaattatta catagatatt
     7981 atttttttag atattgaact tggaaaaagt aatggcgttg acatagcaaa aactatacga
     8041 aaacattcaa aagatactat aatcatcttt gtcacaggtt tttctgacta tgtatttcat
     8101 gggtatgatg taggagcttt gaactacatc ttaaaacctt ataaaactga aaaaatatgt
     8161 aaagtattaa aagaagcact aaaaaaatta gaacaatgga aagaaaactt tattacagtt
     8221 cagattggaa ctaatctttg taaaattaat acaaaagata tcctctactt taaaagtgag
     8281 ctaagaaaat taactgtagt tacctttgat aaaacattag aatactacgg aaaattaaat
     8341 gatatggaaa ctgttcttcc ctctaatttt atacgtacgc atcaaaggta tattgtcaat
     8401 ctaaaccatg tagatagtat aactcaaact tatgccaaag ttcagaatga aaaaattcct
     8461 ataagccgta aaaaatatca agaggttgta ggaaaattta caaggtatat gttagaacct
     8521 taatttttga agttcaatct ctagaatttt atttttgaaa cttaattttt taaagctcag
     8581 tttttagagt tttgtttttt caaatttaat tttttgaagc ttaatttcta gaatttcaat
     8641 ctttcaaaat ttaatttttt gaagcttagt ttttagagtt tttttgaaac ttaatttttt
     8701 aaagcttagt ttctagaatt tcaatctttc aaaatttaat tttttgaagc ttagttttta
     8761 gagttttgtt tcaaatttaa ttttttgaaa cttaattttt aaaatttcaa tctttcaaaa
     8821 ctcaattttt tgaagcttaa tttctagaat tttatttttc aaaatcaatt ctttgaaatc
     8881 taatttccag aattttaatt tttaagattt aattttttaa aacttagttt ccagaatctt
     8941 aattaataga aaggtatatt aaatggacac ttattcttta atctctacaa gcataaattt
     9001 tattctaata ttaatcaata ttttcatagc cttttttctt tataagttga cttcctattt
     9061 tatagacttt aggaatcatt ggattttcaa aatcatattg attttgggct actctattat
     9121 tagtcaaatg ataatatggc tttccgaccc cgtaaatatt ttgtttacac tattcggata
     9181 ttttatacta cttataatat gtagcaaaag caaattaatt cctataatat cagttgtcat
     9241 gatactttat cctattataa ttgggcttaa ttttcttttt ataaacaacc ctatatatga
     9301 ggaacttata cactcaaaag agtatatttt aatactttca atagtccaga taatttctgc
     9361 tctaattaaa ttattatttt ggtttttaat acatattttc ctaaagaata gattggtcaa
     9421 tataaaacaa tacttatcaa ataaaatatg gatttttatt gatatggtat gtatatcttc
     9481 atttttatca atattaattg ctattattct gccacctact aatttaatcc ctatgggtag
     9541 taataagaat attatcttag gcaacttacc ttatggcact tatctaatca tcttgtcagc
     9601 aattctggca aatatcggtg tgatacttct tttacagcca ttgattgaaa atgtaaagat
     9661 gaagatagaa aaacaagcaa atcacctaaa agaaaaatac tataacttac tagaaaatca
     9721 acaaattcaa atacgcaaaa tgcgacatga tatgaataat cactttcaaa tgattgaatc
     9781 gtatttagaa attgaagata ttgctggagc taaaaagtat tttaatcagt taaaaatagg
     9841 tataggtact cttagtggca aacaattttg caaaaaccaa gctcttaact caattttaaa
     9901 tcttcgtcat acaagtttgg aagaaaatgg tgttgatgtg cactttaata tagatataga
     9961 caatcacttg ggtatagaac ctatagattt atgtactatt ttttcaaatt ctttagataa
    10021 cgctatagaa gcatctttga aaattcctga tttgtcaaat agaaaagtgg tattaaaggc
    10081 acgttgtgag aaggagtatt ttagctattt attgacaaac aacaaggtaa atcctatcaa
    10141 tagaaaacaa gaactattta tttcagataa aaaagatagt aattctcacg gatatggtat
    10201 tgagaatatt agagaaattg ttaataagta caatggaaaa ttggatatct cttatactga
    10261 gaatgaattt tctctatttc tttatattag attattttag tctaaaatta gattatctta
    10321 tataatacaa attagattgt tttatactat gtaaaattat aataacttat aattaaatat
    10381 ttacacatat attcattaac ttaaaattta atcaaatgtg atatttttat ttaccttaat
    10441 aaaaatgtgt gtgtctcaaa ataaactttt tagttgatga ggcactcttt tttacatgaa
    10501 atcaaatata tttttatcat ttcaacaatg aaaaagggat ttatctctcc attttgaaac
    10561 aacccctttt tctattaatt actttcttaa aaaatataat acgatatata agataaatat
    10621 ctaattgtac ctatttctaa ttatatctat tagaatacaa cacctttgcc ttttcagtaa
    10681 actccctaac aaaatctagt ttactatctg tataagcatc acgattatgc tcatacttct
    10741 tccaaaggtc caacttaagt ttttcatact cctttgcaac atctgggtgg tcaattaagt
    10801 aatctctaaa aaacaactca tcattatcac ctacatacct tatatgcaaa tgaaaaactc
    10861 gttcttcaaa cccatctact gtataccctt tattaagtga aagcctacta ctgctctcag
    10921 acatacaaat atatccattc gactcaatca aatctttaat atctttcata ttataatcag
    10981 gaattatctc aatcagtatg tcaacaatgg gcttggcata aatcgtactc acagaagtac
    11041 ttccaatatg acttattcta acaatttttt gcattggcaa tattccagtt agtctatatt
    11101 gttcttcttt aaaccaattt ttccaacatt ctttgtgagt agtcaaaaat ataggaaaca
    11161 agttccataa ctcctctaaa gtcatatctt ccaacttctt tttcattagt tacctccttt
    11221 taaatttgta ctttatattt tttctttttc aaatttactt agttaatatt taactttatt
    11281 ttttatcaaa tcatttttct aattatgtaa atttttctaa atttagtttt taatgtatta
    11341 taacagattt ttacccttct tacacttttg catttcttta aatattagaa tattttttaa
    11401 tttacaattg tagtaaaaga tttttcttta cctgtattta ctggcattgg agcttctaaa
    11461 gaataattca ttggctttaa tataattaaa gtaaatttaa catatgtgaa agatacttat
    11521 taaaattatt tatattaatc tcttgttaaa ctttgtattt tttaattatc tatataaaca
    11581 ttaatctgat atgtaggttt tgaattagtt ctattttcaa taggtgtttg ttttgaaagt
    11641 ggataaaata ttgatttagt agtaattaaa tcaatttcaa aatatgtaat agaagataat
    11701 aaacataaaa taactgctat caaaatacca tttctgtact tttcattaaa catactaaac
    11761 actctttttt taatatctga ctccttatgt aatccagcca caaatttatt tgaactattt
    11821 gaaccttttc tcattgcact aattattgtc aatgcataat cctgcttctc ttctatcgta
    11881 caattcttca aaactctttc atcacaataa aattcacaat ccaaatctat aaacttctcc
    11941 attatataca caaaaggatt aaaccaataa acacatttta aaaatatcac caaatactta
    12001 atgtaaaggt ctttactctt aaaatgcatc aactcatgcc taaatatcca gtttaactct
    12061 tttaatgtat aatcacatgg tggtaaaatg acacacgaat taaaaaatac tggactttca
    12121 acttcatatg aatatttaag ccgtattttt ttatttatct taagctcttt taataaattt
    12181 tcataaagat tttttatctt atcatcctca acatcataag acaaatcatt tatcatattt
    12241 ttaagcttaa tatatttcaa taaagtataa actaaataaa atatcgtaat agcaatccaa
    12301 acagagacta aaacagtact atatacaata gaaatactat taaaattgcc taaacttatc
    12361 ttattaatat taccattata ttttgactca ttaaatataa aagtataatt cataaatggt
    12421 aatgatagct taataatcac aataagccat atatagtaat taaatttttt actgaaagtc
    12481 ttaaataaag ttattctaaa gactaataaa ataactataa aaatacaact tactaaaatt
    12541 gttctaaaga tatcatttaa aaatgaacta accacagata ctcacctttc ttatactttt
    12601 atatttatat aatcatctac acgaatacta aattgatatg taggttttta attaactttg
    12661 ttttcaatag gtgattgtct tgaaagtgtt ttaaaagttg atagaataat gatttaggag
    12721 tgataaggtc aattttaaaa tatgtaataa aatataataa gcataaaaca actgctatca
    12781 agataccatt tccaaactct ataagcaaaa ggggctaata caaccttaac cccttttaat
    12841 tattttcatt tataaataaa ttctattctt cccaaaatat cgcaattaaa atatattaat
    12901 taaaatatcc caataagaat atctgaaaaa tcttctacct attttttcaa accctttatt
    12961 cacattcctc atacaatagt gcaactttta gcacagtata aatataccat tagtccatat
    13021 aatctcatta acaaatatat acaattattt tcttcaaact cttttacatc taagatatca
    13081 cattttcatt ttctattaat tccttaactc tctttcaaat taccaatttt ttaatcaaat
    13141 cttcattaaa tattctatca ctattaaaca ttcatcatta tccctaaaaa atatgtgccg
    13201 tatgttcttt acacaaattt tccatcttat catacacagc accactatct ctctcatctg
    13261 tcatagtcac aattatatca cttggtctaa gaattgtctt acctctagga ataatttctt
    13321 ctccacctct ttgaattgct accaaaagac aattttcagg ccactgtaca tcctgaattg
    13381 ccttgttcgc aacaggagag ccaaacataa cagagaactg gtctagtatc ttttcgcccc
    13441 tctctttatg tacaggttct ccattttttt caagtaacct ctcaagaaga ctttcataaa
    13501 taggtttaga cttcataagt gtagccacaa tatatgccac aattgaaatt actgatagtg
    13561 aaagcatttg actaacagaa cctgtcattt caaaaattaa tatgatacca gtcaaagggg
    13621 cacgcacaat agctgtaaaa tatcctgcca tagccaaaag cacaaagtta tttacataat
    13681 cgggattcat tccaaaaact ttaacaccta ccataccaaa tattccacct ataaatgctc
    13741 ctaaaacaag caatggaaaa aatattcccc ctggtgcacc tgacccaaaa ctaacagccg
    13801 aaaatataaa acgtataaca aaaatcaaaa caaccattcc aaaaatatat tcatgacttg
    13861 taagttcttc aactaaattg tgtccactcc ccagaacatc aggcataaca atcccaagaa
    13921 taccagccat tataaatgga atcaacagtt ttccaaaggt agcaatttta ggaatcttct
    13981 tgtataaaga ctgcacatat agagtaaacc agttgtaaaa tgcccccata actccaagaa
    14041 taacacctaa aatcactatt aatccataat aatcttgtgg caacacattt ccaa
//
LOCUS       DACTZW010000101        14018 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.101, whole genome shotgun sequence.
ACCESSION   DACTZW010000101 DACTZW010000000
VERSION     DACTZW010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14018)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14018)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14018
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.101"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(102..1058)
                     /locus_tag="JAM15_16335"
     CDS             complement(102..1058)
                     /locus_tag="JAM15_16335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HAT6799820.1"
                     /translation="MSGLKKFVIFLALLVIAFPVSIYGYVFTKLKTIQDDSINTEALS
                     SNDYKNEENITNILLLGTDARPGEEVSRSDAMMILTIDNKNKSLKLTSLNRDTYVNIP
                     GRGEQKLTHAYVYGQANLLIETIEENFQLDIQNYAVVDFFSFMDIVDALGGVTVTVDK
                     SEIRELNKFIPETYKWNKNDNKGSLKYIRNSGEQKLNGYQTLAFSRIRKNDSTDERDR
                     RQRSVIQSLINGVKDLPVTKYPNLVNTILPYVKTNMNPNEIISLGKELLSIGNLNLKS
                     MEFPLSTENGRKIGNAGYVIPFEEYELDAMHDFIFKDIMVED"
     gene            1426..2214
                     /locus_tag="JAM15_16340"
     CDS             1426..2214
                     /locus_tag="JAM15_16340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAT6799821.1"
                     /translation="MIKLIATDLDGTLLDEKSEINPEFYKVFKKLRERGIMFSAASGR
                     QYQNLIKKFEDIKDDMMFISENGTLVVYKGKEILSNPLNKELVNEIIETTRSIKGKKI
                     VMSGKKYAYIESKDEAFIQEVSTYYAKFKVVEDLTKVEGDILKIAVFDFKGAEHNNNI
                     YFEKFSDRAQVCISGVEWLDLTAKGANKGSAIKKVQKMLDIKYEETMVFGDQLNDVEM
                     MKSAYHSYAMENANEHLKQIARFRAKRNTENGVVDKIKEVIKIG"
     gene            complement(2337..2807)
                     /locus_tag="JAM15_16345"
     CDS             complement(2337..2807)
                     /locus_tag="JAM15_16345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4358 domain-containing protein"
                     /protein_id="HAT6799822.1"
                     /translation="MKKILILFFSIILSLGMVSCSSSGDYKNVSTSKIKKALKSSDLL
                     IKESKIFDAKDFNYFNDVEEDIIQGFVINSSEKLSLEDIIVIKTDEVDKIYKTLENYK
                     KDMIQAPFGEGHGEKINSEIANNTIIEKAGRYVYLISAENATQIENKILNIIKK"
     gene            2946..3590
                     /gene="uppS"
                     /locus_tag="JAM15_16350"
     CDS             2946..3590
                     /gene="uppS"
                     /locus_tag="JAM15_16350"
                     /EC_number="2.5.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010077023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="di-trans,poly-cis-decaprenylcistransferase"
                     /protein_id="HAT6799823.1"
                     /translation="MRIPKHVGIIPDGNRRWASQNGMTKDKGYESGIDPGLESYRLCR
                     DLGCEEVTFYGFTTDNTRRPSVQTKAFTKACIDAANILIDEGAALLVVGNTKSPMFPE
                     ELLPYTNRIKAKEGQIKANLLVNYGWYWDLNNISGVENVNKNNIQDYIQSFDVSRLDL
                     IIRWGGRRRLSGFLPVQSIYADFYVIDNYWPDFKSDDIKDAFSWYDTQDVTLGG"
     gene            3633..4538
                     /locus_tag="JAM15_16355"
     CDS             3633..4538
                     /locus_tag="JAM15_16355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAT6799824.1"
                     /translation="MKKKLLDGKITLIICKSVKIYTKKGEEMSKGNNNNNSRNKSKKT
                     SHLNRKKRKLNKKKLAVLICFTVLFLFIAFKATQGVVALVKSMDKSNKTSQQQNVNSE
                     QFDLGNEEENKKKKYTVFIDPGHGGNDKGTESKTSNRYEKDLNLQIAKKLANKLSKQK
                     DIQVVVSRTDDTYISLKDRAILANNSSADVLVSIHLNAEKNGNTATGIETWYRNKATD
                     GSKELAQTVQSTIVSYVKVRDRGIVENNFEVLRESNMPAILIECGFLTTPSEEQKIIN
                     EKYQDQLAEGIVQGVLSYLDSKGSK"
     gene            4853..6400
                     /locus_tag="JAM15_16360"
     CDS             4853..6400
                     /locus_tag="JAM15_16360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HAT6799825.1"
                     /translation="MNKNSMTKIYSLNKIIFIIIGILGIVLLTRHVGVDIKILILILL
                     TLFSINVFISYLKIKLYEDKINLGLINNSDKFINITKDENFLKHVQNYIISNEKENCV
                     MACFDLCRLKLINDIYGYELGDEVLNNILSNLKYYFGKEAIYGKLKSDVFVLIIKLEN
                     REQKIPYLVNLIKNKIMILSQIDSFKMDINIEASIGIYKFNNNEIDIKKAIDNADMAR
                     LKSKGLKHIEYVEFDNAMEEEIQSIMKIERDLFLAIKNKEFVIHYQPKVDSSTGNIIG
                     SEALIRWLHPSLGMVGPNKFIPIAEKNGLINNIGRWLIQEVFITINKWISEGINVLPV
                     SINLSRVELYKNDLVDFFKLMFNTYNIPKELIELEITETTALRDVKFISERLYEIKSL
                     GMNISLDDFGVGNSNFINLKGIPLDIIKIDRSLILDIVTNTKTKFMVKAIINLSHDLN
                     VTVICEGVEDMHQVKVLSELGCNFIQGYVFFKPLDEMNYKKLLTDGSYINLKDTLLDK
                     CMTVEEE"
     gene            6403..6801
                     /locus_tag="JAM15_16365"
     CDS             6403..6801
                     /locus_tag="JAM15_16365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HAT6799826.1"
                     /translation="MISEDVDYSIRIIRAIFNNGEDKPIDAKMILKSEDIPILTLYRL
                     LRKLCVNNILTFNKEDGKTYMLNVSLDTISLRTIVEVIDGKIYINKCTRYVSNCSNCL
                     KGCKVNRELLEIEKEIYKLLSRKSIRQILE"
     gene            6841..8574
                     /locus_tag="JAM15_16370"
     CDS             6841..8574
                     /locus_tag="JAM15_16370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HAT6799827.1"
                     /translation="MDDISQDNFLLSKEYENSLDVDTKKASGIYYTPKIIVDYIVKKT
                     LKNHDIIKNPYPRILDISCGCGNFLLEVYDILYDLFEENIYELKKKYDENYWTVDNIH
                     RHILNYCIYGADIDEKAISILKDSLTNKKVVNDLDESDIKINLFCCDSLKKKWRYKFD
                     YIVGNPPYIGHKKLEKKYKKFLLEKYSEVYKDKADLYFCFYKKIIDILKQGGVGSVIT
                     PRYFLESLSGKDLREYIKSNVNVQEIVDFLGANIFKNIGVSSCILTFDKKKTKETYID
                     VFKINNEDICINKFETLEELLKSSKFEHFNINQRLLSDEWILVNKDDETFYNKIQEKC
                     KYSLEDIAISFQGIITGCDKAFILSKDDVKLNLVDDKFLKCWIKSKNINKYIVDKSEY
                     RLIYSNDIDNENTNKKILDEIIGLYKTKLENRRECKSGIRKWYELQWGREKLFFERKK
                     IMYPYKSNENRFAIDYDNNFSSADVYSFFIKEEYLDKFSYEYLVGILNSSVYDKYFKI
                     TAKKMSKNIYDYYPNKVMKIRIFRDNNYEEIENLSKQIISILLNKSIDKGKVEKLQIK
                     MDNLIMDSLGI"
     gene            8806..10017
                     /locus_tag="JAM15_16375"
     CDS             8806..10017
                     /locus_tag="JAM15_16375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HAT6799828.1"
                     /translation="MKGLVLEGGGTKGAYQIGAYKALRELGIEFQGVTGTSIGALNGA
                     YIIQNDIEVMEDIWLNYDYTHFMNIDRETYERFKNVDFTTKNLNAVFELINKARKNEG
                     IDISPLRQLMETTLNEDIIRKSKKDFGLVTVWWDKKINPYPLYIEDIPKGRLIDYLIA
                     SSSLPIFQTNMMDDKLYLDGMFCDNMPIGLLEDKGYEDVVVIRLIDDFIGKMNLNRHQ
                     NINIKTIIPSEYLGGSLNKDRDNVEKNIRLGYLDTMKAYERCTGIKYYFDVEYKYNEE
                     YCFDKFRSMSNETIQYICNLLNIKRDASLRTVMESVIPKLGEVLGLPKDFSYKDLFYC
                     IYEKKLEENNINRIKLYDFNKVIDVVNTNIDSNRNLASNFEVRPKISIKKNKNTKLLT
                     NCIIKDIKNQS"
     gene            10209..10469
                     /locus_tag="JAM15_16380"
     CDS             10209..10469
                     /locus_tag="JAM15_16380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002845223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HAT6799829.1"
                     /translation="MEKVVSIKNASGLHARPAGMFVKKAAEFKSTVEVVAKDKTVNAK
                     SIMGIMSLGLAQGEELKLVVNGEDEEVALAAMVELVESGFGE"
     gene            10822..12534
                     /gene="ptsP"
                     /locus_tag="JAM15_16385"
     CDS             10822..12534
                     /gene="ptsP"
                     /locus_tag="JAM15_16385"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HAT6799830.1"
                     /translation="MAYKGIGASPGVALGKALVVEHSELVIEKKSIDNVEAEIAKLED
                     AVAVSKEELVKVKEKASEELGAEEAEIFEAHLLVLEDPELIGSAIDKIKTESVNAEYA
                     LNEIKEMFVSMFESMDNEYMKERAADIKDVTNRILRHILGIKVVDLSALSEEVVLIAH
                     DLTPSDTATMNKKMVLGFLTDIGGRTSHTAIMSRTLEIAAIVGLNDITSKVKDGDFVV
                     FNGDTGEVIVNPDEETINKYTELKAKYEDERKALQLLKGKPSVTLDGKHVELAGNIGT
                     PNDIEGLIKNDAEGVGLYRTEFLYMDRDSFPTEEIQYEAYKAVLEGMDGKPIVIRTLD
                     IGGDKELSYLSMEPEMNPFLGYRAIRLCLDRKDIFKTQLRALYRASIHGRLRIMFPMI
                     SSLEELLQAKEVVKEVLAELDSEGVAYAKDVEIGMMIEVPSAAVISDVLAKHVDFFSI
                     GTNDLIQYTCAVDRMNQKISYLYNQFNPAVLRLIKTVIDNAHKEGKWAGMCGESAGDQ
                     KMIPILLGMGLDEFSMSPISILPARKLITSVKESDMKKLADEVLNMGTAEEIKSYIEK
                     TFNI"
     gene            complement(13326..13991)
                     /locus_tag="JAM15_16390"
     CDS             complement(13326..13991)
                     /locus_tag="JAM15_16390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799831.1"
                     /translation="MKGNIVQYNFADIEEEVYSLDYAIAWNTDEENVNIIPFTNKFCK
                     ESIESFCLGKINNFVEILNEGFVENHHYVHLDKMISVPKKKVNLVYQQDTHGYLLRDD
                     NDNLIPAKITSEQSKSISSKMELFCAGEEKCLINILLKADPSYILDVDSIKDKNILNL
                     GYESIDRYKEYNFDDDKILIFFINKKRYSVIMKKTNNSDNDLVSRNNAIKELFTNKAG
                     NLN"
BASE COUNT         5630 a         1380 c         2273 g         4735 t
ORIGIN      
        1 taatttatat tttaaaataa aaacacaccc cataaataca aagcaatttg catttaagag
       61 gtatgtattt atcatcaaat tattggtttg ttttggaatt tctaatcttc aaccataata
      121 tctttaaata tgaaatcatg cattgcatct agttcatatt cctcaaaagg tattacatag
      181 cctgcattac ctatttttct accattttca gtagaaagag gaaactccat agatttcaaa
      241 tttaaatttc ctatacttaa aagttctttt cctaaagata ttatttcatt aggattcata
      301 ttagttttta catacggaag tattgtgtta actagattag gatatttagt gactggtaaa
      361 tccttaacac catttattaa actctgtata acacttcttt gtcttctatc tctttcatct
      421 gtactatcat tttttcttat acgagaaaat gcaagtgtct gatatccatt taatttttgc
      481 tcaccagaat ttcttatata tttaagagaa cctttattgt catttttatt ccatttataa
      541 gtttcaggaa taaatttatt taattctctt atttcactct tatcaacagt aacagtaact
      601 ccacctaaag catcaactat atccataaaa gagaaaaagt caactacggc gtagttttgt
      661 atatcaagtt ggaagttttc ttctatagtt tctattaata agttagcttg tccatatacg
      721 taggcatgtg ttaatttttg ttctccacgt cctggtatat taacataagt atctctattt
      781 aatgaagtta gcttaagact tttattttta ttatcaatag taagtatcat catggcatca
      841 gaacgagaaa cttcttctcc tggtcttgca tctgtaccta acaataatat gtttgtgata
      901 ttttcttcgt ttttatagtc attactacta agcgcctctg tatttatact atcatcttgt
      961 atagttttta atttagtaaa aacatatcca tatatactaa caggaaatgc tataactaaa
     1021 agggctagaa atataacgaa ctttttgagt cctgacaata atatccccta ctttctaaat
     1081 tttttaatta cacatagtta attatattaa aaatttgtta cataagcaat aaaaaacaca
     1141 ataaattagc ataagtttgt cataatataa ttatttttat agtattttat agaagaaagt
     1201 gtgtagttat tattgatttt attggaatat aattgtatga agacttaaat ttttataaac
     1261 tgatgtgtat attgaaaaaa atattttcct gaatgtagtt atagcatctt atgaaaggtg
     1321 caaattgtaa tttaaaattt ttagtgtata ataagaattg aaaattcaaa ccgataaaaa
     1381 ttaataaaaa ataattataa attaataatt tgggggagga aatgtatgat aaaattaata
     1441 gcaacagatt tagatggaac tttgttagat gaaaagagcg aaataaatcc agagttttat
     1501 aaagtattta aaaaattaag agagagaggg ataatgtttt ctgctgctag tggcaggcag
     1561 tatcaaaatc ttataaaaaa atttgaagat ataaaagatg atatgatgtt tatatcagaa
     1621 aatggaacac tagtagtata taaaggaaaa gaaatattat caaatccttt aaataaagaa
     1681 ttagtaaatg aaatcataga gacaacaaga agtataaaag ggaaaaaaat tgtaatgagt
     1741 gggaaaaaat acgcttatat agaaagtaaa gatgaagcgt ttatacaaga ggttagtact
     1801 tattatgcaa agtttaaagt tgtagaagat ttgacgaaag tagaaggcga tatattgaag
     1861 atagctgtat ttgacttcaa aggtgcagaa cataataata atatctactt tgaaaagttt
     1921 tctgatagag ctcaagtatg tatttctgga gtggagtggc ttgatttaac tgcaaaaggt
     1981 gcaaataaag ggagtgccat aaaaaaagta caaaaaatgt tagatataaa atatgaagaa
     2041 actatggtat ttggtgacca gttaaatgat gtggaaatga tgaaaagtgc ttatcatagt
     2101 tatgccatgg aaaatgcaaa tgaacatttg aaacaaattg ctagatttag agcaaaaaga
     2161 aatactgaaa atggcgttgt agataagata aaagaggtca taaaaattgg atagtcatat
     2221 gtatagatga aaaagattat tttgaagaaa tcaaaaaaat atcaatgtaa ttttgataaa
     2281 taagtttatt tatgctaaaa ttacattgat atttaataaa catcaataat agatatttat
     2341 ttttttatga tattcagtat tttgttttct atttgagttg cattttcagc agaaattaaa
     2401 taaacatatc tacctgcttt ctcaattata gtattatttg ctatttcaga attgattttt
     2461 tctccatgtc cttctccaaa aggtgcttgt atcatatctt ttttataatt ttctagagtt
     2521 ttatatattt tatctacctc gtcagttttt ataacgataa tatcttctag agataatttt
     2581 tcagaagaat taattacaaa accttgaatt atgtcttcct ctacatcatt aaaatagtta
     2641 aagtcctttg catcaaagat ttttgattct tttataagta aatcagaaga ttttaatgct
     2701 ttttttattt ttgatgtaga aacgtttttg taatcaccac ttgaagaaca actaaccatt
     2761 cctaatgata agattatcga aaaaaacaat attaaaattt ttttcatgat aaacctccaa
     2821 gttttttaaa ctctgtctta aattagttta ctacataatt atataaaaat aaatgtattt
     2881 aatgttacag ttttgattaa taatgtaata ttttgataat aatacctatt gagaggtgat
     2941 tagaaatgag aataccaaaa catgtaggaa ttataccgga tggaaataga aggtgggcaa
     3001 gtcaaaatgg tatgacaaaa gataaaggat atgaaagtgg aatagaccct ggattagagt
     3061 cttatagatt atgtagagat ttaggctgtg aagaggtgac tttttatgga tttacaactg
     3121 ataatacaag acgtccatca gtgcagacaa aagcttttac aaaagcatgt attgatgctg
     3181 caaatatatt aatagatgaa ggtgctgctt tattagttgt aggaaataca aaatctccaa
     3241 tgtttccaga agaattatta ccatatacta atagaattaa agccaaagaa ggtcaaataa
     3301 aagcaaatct tctggtaaat tatgggtggt attgggactt aaataatata tcaggagtag
     3361 aaaatgtaaa taaaaataat atacaggatt acatacagtc atttgatgta tccagactag
     3421 atttaataat cagatggggt ggaagaagga gattaagtgg tttccttcct gtacaatcaa
     3481 tttatgcaga tttttatgtt atagataatt attggccaga ttttaagagt gacgatataa
     3541 aggacgcatt tagttggtat gatacacaag atgtcacttt aggtggataa ttaaaaatat
     3601 tctgatttaa ggttgtagag tgttttaaat tattgaaaaa aaaacttctt gatggtaaaa
     3661 taacactaat aatatgtaaa agtgtaaaaa tttataccaa gaagggtgaa gaaatgtcaa
     3721 aaggcaataa taacaataat tcaagaaaca aatctaaaaa aaccagtcat ctgaatagaa
     3781 aaaagcgaaa attaaataag aaaaagttag cagtgttgat ttgctttaca gttttatttt
     3841 tatttattgc atttaaggct actcaaggtg tagtagcttt ggtaaaaagt atggataaaa
     3901 gtaataaaac tagtcaacaa caaaatgtta actcagaaca atttgacctt ggtaatgaag
     3961 aggaaaataa aaagaaaaaa tatactgtat ttatagaccc aggtcatgga ggcaatgata
     4021 aaggaactga aagcaagacc agtaatagat atgaaaaaga cctaaatcta caaattgcaa
     4081 aaaaattagc aaataaatta tctaaacaaa aggatattca agtagtagta tccagaactg
     4141 atgatacata tatatcatta aaggatagag ctatcttagc aaataatagt tctgctgatg
     4201 tgcttgtttc tattcattta aatgcagaga aaaatggtaa tacagcaaca ggtatagaaa
     4261 cttggtatag gaataaagct acagatggtt caaaagaact tgcacagaca gtacaaagta
     4321 ctatagtatc ctatgttaaa gttagagata ggggaatagt tgaaaataac tttgaagtac
     4381 ttagagaatc aaatatgcct gctatattaa tagagtgtgg ttttttaaca acaccttcag
     4441 aggaacaaaa aataataaat gaaaaatatc aagaccaact tgcggaagga attgttcaag
     4501 gtgtactttc atacctagat tctaaaggga gtaagtaagt taagtttact ttaatgtgag
     4561 gataaattta aaagtttaac tgtgtaaatt gtattaactt tatttcgtaa tgttggaaac
     4621 attgtttgaa tttagaaact atgaaattag aaattatttt atctatatct aatttcatag
     4681 ttttttttgc aaaaaattta tagttataaa atttaaaaaa ataaatttag tataatgtaa
     4741 tgtagttatt tatatgtgat tttaacttgc attgatttgc tatcaattgt gctttataat
     4801 tagtatatat aaagtttaac tgtaagataa tttaaaaaat aggggaattt atatgaataa
     4861 aaatagcatg acaaaaattt acagtttaaa taaaataatt tttattataa ttggaatttt
     4921 aggaatagtt ttacttacaa gacatgttgg ggtagatatt aaaattttaa ttttaatttt
     4981 attaactttg tttagtataa atgtatttat ttcatatctt aaaattaagt tgtatgagga
     5041 taaaattaat ttaggattga taaataattc agataagttt ataaatatta ctaaagatga
     5101 gaacttccta aaacatgttc aaaattatat tatcagtaat gaaaaagaaa actgtgtaat
     5161 ggcttgtttt gatttatgta gactcaaact tataaatgat atatatggtt atgagctagg
     5221 ggatgaagtg ttaaataata ttttaagtaa cttaaaatat tattttggaa aagaagctat
     5281 ttatggaaag ttaaaaagtg atgtttttgt attaataata aagcttgaaa atagggaaca
     5341 gaagattcct tatttagtaa atcttattaa gaataaaatt atgatattaa gtcagattga
     5401 cagttttaaa atggatataa atattgaggc ttctattgga atttataaat ttaacaataa
     5461 tgaaattgat ataaaaaaag ctatagataa tgctgatatg gcaaggctta aatcaaaagg
     5521 actaaagcac atagagtatg tagaatttga taatgctatg gaagaagaaa tacaatcaat
     5581 tatgaaaata gagagagatt tattcttggc tattaaaaat aaagagtttg taattcacta
     5641 tcaacctaaa gttgattcaa gtacaggtaa cattataggt tcagaggcat tgataagatg
     5701 gttgcaccca tcattaggca tggttggacc aaataagttt atacctatag ctgaaaaaaa
     5761 tggtctgata aacaatattg gtagatggct aattcaagaa gtttttatta ccattaacaa
     5821 gtggatttca gaaggtataa atgtcttacc agtctcaata aatctttcta gagtagaact
     5881 atataaaaat gatttagttg atttttttaa actgatgttt aatacatata atattccaaa
     5941 agaacttata gaattagaaa ttacagaaac gacagcgcta agagatgtaa aatttataag
     6001 tgaaaggctt tatgagatta aatctttagg tatgaatata tcattagatg attttggagt
     6061 aggtaattca aattttatca atcttaaggg gataccacta gatattataa aaattgatag
     6121 gtcacttata ttggatatag ttacaaatac aaaaacaaag tttatggtga aagcaattat
     6181 taacctttca catgatttaa acgtaactgt tatatgtgaa ggggtagagg atatgcatca
     6241 ggtcaaagtc ttaagtgaac tgggatgtaa tttcatacaa ggttatgtat tttttaaacc
     6301 tttggatgag atgaattata aaaaacttct tactgacgga agttatataa atctgaaaga
     6361 tactctttta gataaatgca tgacagttga ggaggagtaa ggatgatttc agaagatgta
     6421 gattattcaa taagaatcat aagagctata tttaataatg gagaagataa accaatagat
     6481 gctaaaatga tattaaaaag tgaagatata ccaatactaa cactatacag actgcttaga
     6541 aagctttgtg taaacaatat tcttactttt aacaaagaag atggcaagac atacatgtta
     6601 aatgtgtcat tggatacaat aagtctaaga actattgtag aagtaatcga tggaaaaata
     6661 tatataaata aatgtacgag atatgtatct aattgcagta attgcttaaa aggttgtaaa
     6721 gtaaatcgtg aattgctaga aatagaaaaa gaaatttata aacttttatc gagaaaatct
     6781 ataagacaaa tactagaata aaaaattttc agctatgata ataattggag gttttcggtt
     6841 atggatgata tatctcaaga taattttcta ctgtctaaag agtatgagaa tagcttagat
     6901 gtagatacta aaaaagcaag tggaatatat tatactccta aaataattgt agattatatt
     6961 gtaaaaaaaa ctttaaaaaa tcacgatata attaaaaatc catatccacg aatacttgat
     7021 atttcctgtg ggtgtggaaa ttttctttta gaagtatatg atattttata tgacttattt
     7081 gaggaaaata tatatgaatt gaaaaagaag tatgatgaaa attattggac tgttgataac
     7141 atacaccgtc atatattaaa ctattgtata tatggtgctg atattgatga aaaagctata
     7201 agtatattaa aagatagctt aacaaataaa aaggtagtaa atgatttaga tgaatctgat
     7261 ataaagatta atctattttg ttgtgatagt cttaaaaaga aatggcgata taagtttgat
     7321 tacatagtgg gtaatccacc ctatattggt cataaaaaac ttgaaaagaa atataaaaaa
     7381 tttctcctag aaaaatatag tgaagtttat aaggataaag ctgacttata tttttgtttt
     7441 tataaaaaaa ttatagatat tttaaagcaa ggaggggttg gcagtgttat aactccaaga
     7501 tatttcttag aaagtctatc aggtaaagat ttaagagaat atattaaatc aaatgtcaat
     7561 gttcaagaaa tagtggattt tttaggtgca aatatattta aaaacatagg ggtatctagt
     7621 tgtattctaa cttttgataa gaaaaaaaca aaagagacat atatagatgt atttaaaatc
     7681 aacaatgagg atatatgtat aaataaattt gaaacattgg aagaacttct aaagagtagc
     7741 aaatttgaac attttaatat aaatcagaga ttgctatctg acgaatggat acttgtaaat
     7801 aaagatgatg aaacttttta taataagata caagaaaaat gtaaatatag cttggaagat
     7861 atagcaataa gttttcaagg aataattaca gggtgtgata aagcgtttat tttaagtaaa
     7921 gatgatgtaa agttgaacct tgtagatgat aaatttttaa aatgttggat aaaaagtaag
     7981 aatataaata aatatatagt agataaaagt gaatataggc taatatactc aaatgatata
     8041 gataatgaga atacaaataa aaagatacta gatgaaatta tagggctata taaaacaaaa
     8101 ttagaaaaca gaagagaatg taaaagtgga ataaggaaat ggtatgaact tcaatggggt
     8161 agagaaaagc ttttctttga aagaaaaaag ataatgtatc cttataaatc aaatgaaaat
     8221 agatttgcta tagattatga taacaatttt tcaagtgcag atgtatattc tttttttata
     8281 aaagaagagt atttagataa attttcatat gaatatctag ttggaatttt aaattccagt
     8341 gtttatgata aatactttaa aataactgct aaaaaaatga gtaaaaatat atatgattac
     8401 tatcctaata aggttatgaa gataaggatt tttagggata ataattatga agagatagag
     8461 aatttatcaa agcaaataat atcaatttta ttaaataagt ctatagataa aggaaaagta
     8521 gaaaaattgc agataaaaat ggataacttg ataatggatt ctttaggtat ataagcagtt
     8581 gtaagtatta aaaaattata atcctttaat tgtttattta aatttagaaa taaaaagtta
     8641 gccatataaa aaatattaaa aatatatact tttcaatatt tttttgataa aataagaatg
     8701 aatttgtgca attttatttt tctccaataa ctaaaaatag ttttttgaat taatatttgc
     8761 ttaagaataa aaatcagaaa cgtttttgat atagtaggtg ataatatgaa aggattagtt
     8821 ttagaaggtg gaggaacaaa aggagcctac caaataggtg catataaagc tttaagagag
     8881 cttggtatag agtttcaagg agtaactggc acatcaattg gtgctttaaa tggagcatat
     8941 ataattcaaa atgatattga agtaatggaa gatatttggt taaattatga ctatactcat
     9001 tttatgaata ttgatagaga aacctatgag aggtttaaaa atgtagattt cactactaaa
     9061 aatctcaatg cagtgtttga gcttataaat aaagctagaa aaaatgaagg tatagatata
     9121 agcccattaa gacaactaat ggagacaaca ttaaatgaag acataataag gaaatcaaaa
     9181 aaagactttg gacttgttac tgtctggtgg gataaaaaaa ttaatccata tccattgtat
     9241 atcgaagata tacctaaagg aagattgatt gattatttaa ttgctagttc cagtttgcct
     9301 atttttcaaa cgaacatgat ggatgataag ttgtatcttg atggaatgtt ttgtgataac
     9361 atgccaatag gactcttgga agacaaaggt tatgaagatg ttgttgtaat taggttgatt
     9421 gatgatttta ttgggaaaat gaatctaaat cgacatcaaa atataaatat aaaaactata
     9481 ataccatcag aatatctagg aggttctctt aataaagata gagataatgt agaaaaaaac
     9541 atccgactag gttacttaga tactatgaaa gcatatgaaa gatgcactgg aattaagtat
     9601 tattttgatg tagagtataa atataatgaa gaatattgtt ttgataaatt tagaagtatg
     9661 agcaatgaaa caatacaata tatctgtaat ttattgaata taaaaagaga tgcttcactt
     9721 agaactgtta tggaaagtgt aataccaaag cttggtgagg tgcttggatt gccaaaggac
     9781 ttttcatata aagatttgtt ttactgtata tatgaaaaga aacttgaaga aaataatata
     9841 aacaggataa aattatatga ttttaacaag gttatagatg ttgtaaatac aaatattgat
     9901 tctaatagaa atttagcttc taattttgaa gttagaccta aaattagtat taaaaagaac
     9961 aaaaacacaa aattattgac aaattgtatt ataaaagaca taaaaaatca aagttaaata
    10021 aaaaacaaaa aaaaatttgt aattatactc gaaaaaagtg tatattagta gtataatatt
    10081 tttgtagcac tagtgggaac aaaaaatgac cataggacaa aaaagtacca cttagtacca
    10141 ttagagtaaa aaacaggaaa acaattttaa aaaatataaa atgtaaagtt tataggagga
    10201 tttaaaaaat ggaaaaagta gttagtatca aaaatgcaag tggattacat gctagaccag
    10261 caggaatgtt tgttaagaag gcagctgaat ttaaatcaac agtagaggtt gtagcaaaag
    10321 acaaaactgt aaatgcaaaa tcaataatgg gaataatgag tttaggttta gctcaaggag
    10381 aagaattaaa gttagttgta aatggagaag atgaagaagt agctttagct gcaatggttg
    10441 aattagttga aagtggattt ggagaataga tataataatt ttttaaaatt tgatatttag
    10501 aatctaatat tacttaaagt aaagtaacag agaagtatta aacatataca gaccaacatt
    10561 tgtagatatt taatttcttt gttactttca tgtttattta atcagaagat taagactatt
    10621 gttaattgga tataaaaata taaatatttt agaaaatgaa ataagatatt tttaatcata
    10681 aattcagagt aaaaatacag taacaaacag tttataaaat ttaataaaaa attataagta
    10741 aataaaacta taaaaatgta aattatttat ataaatttat agagtttatg tgctagatga
    10801 tattttttag gaggtagggt tatggcttac aaaggaatag gtgcttctcc tggtgttgct
    10861 ttagggaaag cgttagtagt tgaacatagt gaattagtaa ttgaaaaaaa atctatagat
    10921 aatgttgaag ctgaaattgc taaattagaa gatgcagttg cagtttctaa agaagaatta
    10981 gtaaaagtta aggaaaaggc ttctgaagaa ttaggagcag aggaagcaga aatatttgaa
    11041 gcacatttat tagttttaga agacccagag ttaattggtt ctgcaataga taaaattaaa
    11101 actgaaagtg taaatgcaga gtatgcttta aatgaaataa aagagatgtt tgttagcatg
    11161 tttgagtcta tggacaatga gtacatgaaa gaaagagcgg cagatataaa agatgttaca
    11221 aatagaatac ttagacatat attaggaatt aaagttgttg atttatctgc tttaagcgaa
    11281 gaagttgtat taatagcaca tgatttaact ccatcagaca cagcaactat gaataaaaaa
    11341 atggttttag gatttttaac tgatataggt ggaagaactt ctcatactgc tatcatgtct
    11401 agaactttag aaatagctgc aatcgttgga ttaaatgata taacttcaaa agttaaggat
    11461 ggagattttg tagttttcaa tggagacaca ggtgaagtaa ttgtgaatcc tgatgaagag
    11521 actataaata aatatactga attaaaagct aagtatgaag atgagagaaa agcattacag
    11581 ctattaaaag gaaaaccatc tgtaacttta gatggaaaac atgtggaatt agctggtaac
    11641 ataggaacac ctaacgatat agaaggtcta ataaagaatg atgctgaagg tgttggtctt
    11701 tatagaacag aatttttata catggataga gattctttcc caacagaaga aatacaatat
    11761 gaagcataca aagctgtatt agaaggaatg gatggaaagc ctatagttat aagaacattg
    11821 gatataggtg gagataaaga attaagttat ttaagtatgg aacctgaaat gaatccattc
    11881 ttaggttaca gagcaataag actttgccta gatagaaaag atatatttaa gactcaattg
    11941 agagctttat atagagctag tattcatgga agattaagaa tcatgttccc aatgatttca
    12001 tctttagaag agttgttaca agctaaagaa gttgtaaaag aagttttagc agaacttgat
    12061 tctgaaggtg tggcttatgc taaagatgta gaaattggta tgatgataga agttccatct
    12121 gctgctgtaa tatctgatgt attggctaaa cacgtagatt tcttctctat aggaactaat
    12181 gatttaattc aatacacttg tgcagttgat agaatgaatc aaaagataag ttatctttac
    12241 aatcaattta atccagctgt tttaagactt ataaagactg ttatagacaa tgcacataaa
    12301 gaaggaaaat gggcaggtat gtgtggagaa tctgccggag accaaaaaat gataccaata
    12361 cttttaggta tgggattaga cgagttctct atgtctccaa tatcaatact tcctgctaga
    12421 aagttaataa cttcagttaa agagtcagat atgaaaaaat tagctgatga ggtacttaat
    12481 atgggtactg cagaagaaat aaaaagctat atagaaaaga cttttaatat ataattaatg
    12541 ttatatagtt actaaaattc atttttctaa ataacaaaat tatattttac gaattaaaaa
    12601 ggagatgttt caaaataaaa atttgaagca tctctttttt ataaaagatt attaagaatt
    12661 acttaatctt tgtaatagtc attttgtgaa aaagcaaaac tgcattgtga ctatagtata
    12721 tatggatgtt attatcaata aaagtactat taaaatgaag attcattctc aaatggcatc
    12781 aaaagtagtt gtgatggagt aagataatat tttgtgattt aatagtaaaa attaaaaaaa
    12841 tatggtattg aaaaataatt aaaagtattt aataatagaa ttagggaaga ataagtttat
    12901 aattaaaaat aattgattag tagttaataa aataaatgtg atatccaaat aaatcctaaa
    12961 tctaatttga gttttaatat agatagtcta aagtttgatt attaaagatt taattgtaag
    13021 ttgttacagt tgatgatatt gattagagat taaagtttag agtagaaagt taccttaaat
    13081 ttaaaaatgc aagataaccc aatctaaaaa ttataatcac tcgataggtt taaggattta
    13141 tttgtttatt ataaatagga gggtgtctca aaatgaactt tttagtttat gaggcactct
    13201 cttttatata gaattaaata tattttatta tttcaacaat gaaaaagaag cttatctcta
    13261 ttttgagaca gcctctttgt atactattat taatttaatc aataatataa tttaaaatta
    13321 taatattagt taagatttcc tgctttatta gtaaataatt ctttaatagc attgtttctg
    13381 gaaactaaat cgttatcaga gttgtttgtt tttttcataa tcactgaata acgtttttta
    13441 tttataaaaa atattaaaat cttatcatca tcaaaattgt attctttata tctgtcaata
    13501 gactcataac ctagatttag aatgtttttg tcttttatac tatctacatc taaaatatat
    13561 gatgggtcag cctttagtaa tatattaatt aaacattttt cttcaccagc acagaataac
    13621 tccatcttac ttgatataga tttagattgc tctgaagtta tttttgcagg aataaggttg
    13681 tcattatcat ctcttagaag ataaccatgt gtgtcttgtt gatatactaa attaaccttt
    13741 ttcttaggaa cactaatcat tttatctaaa tgtacataat gatgattttc aacaaaacct
    13801 tcatttaata tttcaacaaa gttattaatt ttacctaggc aaaaagattc tatagattct
    13861 ttacagaatt tatttgtaaa tggtattatg tttacgtttt cctcgtctgt attccatgct
    13921 atagcataat ccaacgaata tacttcttcc tctatatctg caaaattata ttgtactatg
    13981 tttcctttca aaattactcg acctccatct tataatat
//
LOCUS       DACTZW010000102        13938 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.102, whole genome shotgun sequence.
ACCESSION   DACTZW010000102 DACTZW010000000
VERSION     DACTZW010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13938
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.102"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            339..950
                     /locus_tag="JAM15_16395"
     CDS             339..950
                     /locus_tag="JAM15_16395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799832.1"
                     /translation="MNIKRINLLLSTVMAAVIISLPLAVTANAMEKTESDNNVKIELS
                     DKEVEELHNYWPEDKIFSDEKIDEILIKTGQFTQKELDKINQEVDDSAKKVNQNSRVK
                     YINGYNKYRTFTKNGKNYLYIYVSGKTLKKIKAGTDLASTFGGFLPKIWVELDVVAIG
                     KIITINMDGINTNYGIVLSYIENKWNFQGVTYTYRYDHWFYQT"
     gene            978..1160
                     /locus_tag="JAM15_16400"
     CDS             978..1160
                     /locus_tag="JAM15_16400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799833.1"
                     /translation="MKKRLYKVFLKTIPNLIIVILSLALSFYTNTFDIDLKILLLIPL
                     AYVLLFIYYYIKTKKD"
     gene            1400..1942
                     /locus_tag="JAM15_16405"
     CDS             1400..1942
                     /locus_tag="JAM15_16405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAT6799834.1"
                     /translation="MLIYLAILELEEDKIKFEKVYEKYRQIMFYVANKILKDDHLSED
                     AVHNAFLRIIKNIDKIDEVDSPRTKAFIVIIVERIAIDFYRKRKREKVSDIEEEYKNR
                     EINFSIEDKVCESNLAIALAKLNESYFQVLSLKFQYGFSNKEIANALNLGEENVYKRI
                     QRARKKLKEILEEMEVGNIE"
     gene            1974..2636
                     /locus_tag="JAM15_16410"
     CDS             1974..2636
                     /locus_tag="JAM15_16410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4367 domain-containing protein"
                     /protein_id="HAT6799835.1"
                     /translation="MLRESIPIATKIIIDDLPSDDELNHVFSKGFERKMKKLIKQQKR
                     SSLTNKIIFYSKQTAIVFLIVLASLFTITMSSEALRSRFFRLVIRVYEDLTSFVFSTN
                     EEDNLSLKNKEPEYIPKGFKEVDRIDDFVITYRNDENIEIQYVTDKISSNSIILDTEN
                     AKVKDIFVNGHKAKYIVKGTFLQLFWNDNNFIYLLNVDYQNSGESEFYEDILIKIAKS
                     IK"
     gene            2826..3143
                     /locus_tag="JAM15_16415"
     CDS             2826..3143
                     /locus_tag="JAM15_16415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799836.1"
                     /translation="MKSDLYLCKSNKLYRDNEVLEKFMEDLSFLIDDYKFSLETISIL
                     CKINIEKLTNFYAGKGYILYEEMSLIESVLAPFLSAIDIAKHNYDVVIKSRESDKPLI
                     FEN"
     gene            3165..3608
                     /locus_tag="JAM15_16420"
     CDS             3165..3608
                     /locus_tag="JAM15_16420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799837.1"
                     /translation="MKRLFALLLTLSLVILPSTLVFANEKAENDSIYAEAPLVFQSNE
                     KASTHGSGGTAYIGYMSSKHLNWRITSSKGIVILFSGTVEIRNSKNMLVASYPISGGG
                     SSTISGQIDVKYLKKGDYKAILKGTGTTGGGVLVVKSGLVQMFTI"
     gene            3826..4269
                     /locus_tag="JAM15_16425"
     CDS             3826..4269
                     /locus_tag="JAM15_16425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799838.1"
                     /translation="MNLRKTVISGMCALVCSSAVAIPAFADEYQDKNIEQYSAVNYID
                     DTMVKMSYIKSGTCNLSISGSTAKVTCFVRGASNVTSTSIIARLQKSNDNGKTWSTIQ
                     TWNASGNISCSLSKSKTIGKGYYRVHSTIKANSESKNIISSTKKY"
     gene            complement(4400..4820)
                     /locus_tag="JAM15_16430"
                     /pseudo
     CDS             complement(4400..4820)
                     /locus_tag="JAM15_16430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894307.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(4798..6075)
                     /locus_tag="JAM15_16435"
                     /pseudo
     CDS             complement(4798..6075)
                     /locus_tag="JAM15_16435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899679.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
     gene            complement(6098..6640)
                     /locus_tag="JAM15_16440"
     CDS             complement(6098..6640)
                     /locus_tag="JAM15_16440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799839.1"
                     /translation="MLLCDPASAGGSKHDYSAFLVGSESENGLLCGRLAELAKINART
                     DFDKYILHMIYLLKVYPDITHVYIEKNTFNGTAANQLELKIKNDDVLYYRDIEIINEH
                     QKKNKDDKISTLIPVLNKGQMIFAEEDKAFIQQILNFTGQKYSLHDDAPDISAEFINR
                     IFNIKVNESITLLDRRNLGL"
     gene            complement(6680..6898)
                     /locus_tag="JAM15_16445"
     CDS             complement(6680..6898)
                     /locus_tag="JAM15_16445"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799840.1"
                     /translation="MLFDFKNTNHLEDAKEFYWENEKEIKFPILWPSFWNCLDMALSY
                     YENPTSFKQEVQNDVNSIGEKWFKTIRT"
     gene            complement(7094..7837)
                     /locus_tag="JAM15_16450"
     CDS             complement(7094..7837)
                     /locus_tag="JAM15_16450"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799841.1"
                     /translation="MDNLERNIQLIFSYMAKTFIRNGATIREAEKEANEIIKTNSSNL
                     WGVNGLAYQLGKINLEFFCMYFIQDTYLPKEDNVATPIAKVHHELWEDIQESIIGDGS
                     QQLGRIYPRGTGKSAFGDLATTVWSHCYKHKTYTLIYSDIGSTAEKFVKDIKNALLEN
                     EYIKKAFGVLLNDNDRKYICNSTQLELTNKTFIEAISSSSPMRGKKYNNNRPDLIILD
                     DYQSEENVRTEDAREKKFKRFSDDVKYAA"
     gene            complement(8137..8694)
                     /locus_tag="JAM15_16455"
     CDS             complement(8137..8694)
                     /locus_tag="JAM15_16455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAT6799842.1"
                     /translation="MVVGYMRVSTAEQNEDRQLVTMKKHNVEKMYQEKISAKDTKRSK
                     LNAMLDFVREGDTIIVHDFSRLARSTKDLLEIVELLEKKHVKLISDKENLDTSTPTGK
                     LMLTMLGAIYEFERTNMLERQREGISIAKEQGKYKGRKEVKIDNFGSYYDRYKTRELN
                     KTQLAKELGVSRPTLDRLIKSHESN"
     gene            complement(8889..9077)
                     /locus_tag="JAM15_16460"
     CDS             complement(8889..9077)
                     /locus_tag="JAM15_16460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799843.1"
                     /translation="MNNKKKSFLISGTINVILLIIVFALFSYNIIENSTRNMIITVIL
                     IFIFEIIKIKILEKYYNL"
     gene            complement(9088..9663)
                     /locus_tag="JAM15_16465"
     CDS             complement(9088..9663)
                     /locus_tag="JAM15_16465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799844.1"
                     /translation="MLKKKIISFLMAGIFVLSSGYNLVYASTFEENEYKQELVNENEF
                     TIINSNENEMIVDKKGNNTYVSTKVTPGSWKNVKYLGQKSRKLSSPYTRERIIQTIQW
                     GLGYLSGGSSFLLGLAESIYREKVYDITKYGGVYTKTYYRRQITDIRNSHANVPVPYR
                     YEYVTYFYSSSNFKKVVYTERVGDGIKLANN"
     gene            complement(9996..11135)
                     /locus_tag="JAM15_16470"
     CDS             complement(9996..11135)
                     /locus_tag="JAM15_16470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HAT6799845.1"
                     /translation="MVIKLTIEEYKNKYSTGDKIILSLKSFDNKELYYHETDNILNSK
                     DEIDRLTSSKIFKIIEDKNDLALESYYSSVIEGAFSTRKIAKSIIRGKMKPSNKSEYM
                     IYNNHRALEYGLDNLDKLYSHKFIYNLHHILGENCLDSEEYEYRTEKVYVCDSKGEII
                     HTGLDPLKIYNFMDELIIFMENSKVNDLVKSTIIHFYFVYVHPFSDGNGRTSRALSYL
                     YLINKGYDTFKEFSISYIISKNRTKYYKAILDVENKGYNLTVFIEFMLKSIIQSINEM
                     RDMHDRKSLESILKEELFENDITLSATEEHILKYICSKDNYSMTLENYIKKNKGRYLK
                     AGIKEIELVDQLMEVFNNLEEIEILSREKDVYKVNEKYLNMLEIS"
     gene            11472..12725
                     /locus_tag="JAM15_16475"
     CDS             11472..12725
                     /locus_tag="JAM15_16475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799846.1"
                     /translation="MLNKKNISSIIMTMILSLSTTVFVFADENTNVKGQDITKYNEEM
                     VSKNLEDLSIEQLIDIRDKAIDKNLEGLRKFGEDSVKERKDSILNFEFGLVAFVNKNY
                     SNLTEKEKLIRQINIVEYENSINDIMDPSGDFFKVTNQSYQINEFVLKNGKNYKEWSY
                     EYVEFLIEHLEDLCNFVDFDAKYVIEMLDPSIKPDLSDNQKKSLNNELIKMYSSNTLS
                     TNIKDEIENWENNLNINEKNSNEPLPRVSPSSYRQQALAYAKKHGYTNGYYGSTNRKN
                     NAPSPYYNFQKDGYGDCANFVSQCLHEAGVTFWTNNNPWYYYSTSNRSPSWAGAREFK
                     IHWMNRIAYQTLTVSNSLSFLRPATPVSILNSSGVATHTLISTDKHSNGYNFSYAAHS
                     DEGARTNLLKKLEGKKISYYKVYWE"
     gene            13059..13790
                     /locus_tag="JAM15_16480"
     CDS             13059..13790
                     /locus_tag="JAM15_16480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799847.1"
                     /translation="MLNKKNVSLIVLVIVLSLFTAIFVFNNRNTNDKSKEIAKNNEEI
                     VPKNLEALSIEQLTKIRDKAIDKNLEGLREFGEDSVKQRKDSILNFEFGLVAFVNKNY
                     SNLTEKEKLIRQINIVNYENSINDIMDPSGSFFELANQSYEINEFMLKNKKNYKEWSY
                     EYIEFLIDHLDELCKFVDFDIKDVIDIIDPTIKTDLSEEQKKSLNDKLKKVSSSDTLS
                     EDIKKEIKNWENNLNSLNMNKNNSN"
BASE COUNT         5122 a         1783 c         1741 g         5292 t
ORIGIN      
        1 taaattttta ttcaaagaat acacataaat atttccagac tcacttattt gtataagtta
       61 tattctattt tgtatgaagt caattaaaaa ctgaactata ttaaaattaa ttttataaat
      121 aacaaatata aataattaca aaaccttaac tgcgttaagt ttgaaatata ataatattaa
      181 aaacacttct ctcaaatcaa gtatcttttg ttatattttc ataagtttta aaaatataaa
      241 ttttttaaaa cttgtgtcca aaaaacaaaa ttaaatatgt tatatatgta aagggttaat
      301 tttaaaacct taaatttctt atagttaggg ggatttaaat gaatatcaaa agaattaatc
      361 tccttttatc aacagtgatg gcagctgtga taatatcttt accacttgct gttacagcaa
      421 atgcaatgga aaaaacagaa tcagataata atgtgaaaat agagttgtct gacaaagaag
      481 tagaggaatt acataattac tggcctgagg ataaaatttt ttcagatgaa aagattgatg
      541 aaatcttaat taaaacaggt caatttactc aaaaggaatt ggataaaatc aatcaagaag
      601 tggatgattc tgctaagaaa gtaaatcaaa attctcgtgt gaaatatata aatgggtata
      661 acaaatacag aacttttact aaaaatggta aaaactattt atatatttat gtaagtggaa
      721 agacattaaa gaaaataaaa gctggaacag atcttgcatc tacttttgga ggttttttac
      781 caaaaatttg ggtagagctt gatgtagtgg caattggaaa gataataaca attaacatgg
      841 atggtataaa tactaattat gggattgttt tatcatatat agagaataag tggaattttc
      901 agggtgtaac atatacttat agatatgatc attggttcta tcaaacttaa aagacatgct
      961 tttttaggag gaataatatg aaaaaaaggc tttataaggt ttttttaaaa acaattccaa
     1021 acctgataat tgtgatatta tcacttgcat tatcatttta tactaataca tttgatattg
     1081 atttaaaaat attgctttta atacctttag catatgtact tttgtttata tactattaca
     1141 tcaaaacaaa aaaagattaa tttttatgga attagatata tacgaaaata attaatttaa
     1201 aaatttaact ttgagaatta tttgtagagt taaggccctt ataatcccga aaatggattt
     1261 gaagggcctt tttactagat atctttaaaa agcttgttaa gcatagttat attctattta
     1321 agtagagtta attatatatt tatgttataa ttgaacttta aaatattaat tcagaatttt
     1381 tatattggag gaattctaaa tgttaattta tctagctata cttgaactcg aagaagataa
     1441 aataaagttt gaaaaggtat atgaaaagta tagacaaata atgttttatg tagccaataa
     1501 aatattaaag gatgatcatt tatcagaaga tgcagtacat aatgcttttt taagaataat
     1561 taaaaatata gataaaattg atgaggtaga cagtccaaga acgaaggctt ttatcgttat
     1621 aatagtagaa aggattgcta tagactttta cagaaagaga aaaagagaaa aggtatctga
     1681 tattgaagaa gagtataaaa acagggagat aaatttttct atagaagata aagtatgtga
     1741 aagcaattta gctatagcac ttgcaaaact taatgaaagt tactttcaag tgctttcctt
     1801 aaagttccag tatggttttt caaataaaga aatagcaaat gcattaaatt taggggagga
     1861 aaatgtatat aagagaattc agcgtgctag aaaaaaatta aaagaaatat tagaagaaat
     1921 ggaggttgga aatattgagt aataaaaaag atgattttga tattacggat gatatgctta
     1981 gagaaagtat cccaatagcg acaaaaatta ttattgatga ccttccttca gatgatgaat
     2041 taaatcatgt tttttcaaaa ggttttgagc gaaaaatgaa aaaactcatt aagcaacaaa
     2101 aaagaagtag tcttacaaat aaaatcattt tttattcaaa acaaacagct attgtatttt
     2161 taatagtttt agctagttta tttactatta ctatgagtag tgaggcattg cgttcacgtt
     2221 tctttagatt agtaataaga gtatatgaag acttaacttc atttgttttt tcaactaatg
     2281 aagaagataa tcttagttta aaaaataaag aacctgagta tataccaaaa ggatttaaag
     2341 aagttgatag aattgatgat tttgttatta catatagaaa tgatgaaaat attgagatac
     2401 aatatgtaac agataaaatt agttcaaatt ctattatatt agatacagaa aatgcaaaag
     2461 ttaaagatat atttgtaaat gggcataaag caaaatatat agtaaaagga actttcttac
     2521 agttattttg gaatgacaac aactttatat atttattaaa tgtagattat caaaatagtg
     2581 gagaatctga attttatgaa gatattttga taaaaatagc gaaaagtata aaataatttt
     2641 tttaagtgtc caagggtagc ctcttcattc gttatacaag tatatatgaa aatgtgaggt
     2701 gatttttatg gttttaaaat ctacatttac ctgagcgtta aaaatattgt tataggaaaa
     2761 attaatacat tatagttata acatgcttgc aataggaata aaactttaaa attgaggtgt
     2821 aaaaaatgaa atcagattta tatttatgta aaagtaataa attgtataga gacaacgaag
     2881 ttctagaaaa atttatggaa gatttaagtt ttcttataga cgattataaa ttctcgttag
     2941 aaacaatatc tattctatgc aaaataaata ttgagaaatt aactaatttc tatgcaggaa
     3001 aaggatatat actgtatgaa gaaatgtctc ttattgaaag tgtacttgca ccttttttaa
     3061 gtgcaattga tattgctaaa cataattatg atgttgtcat taaatcgagg gaaagcgata
     3121 aacctttgat attcgaaaat taatttaaaa ctgggggaat acacatgaaa agattatttg
     3181 cgttattact tactttaagt ttagttatat taccatcaac tttagtattt gctaatgaaa
     3241 aagctgaaaa tgattcaatt tatgctgagg cgccattagt gtttcaaagt aatgaaaaag
     3301 catctacaca tggtagtgga ggaactgcat atataggtta tatgtcaagt aaacatctta
     3361 attggaggat aacatcttca aaaggaatag ttatactatt ttcaggaact gttgagatta
     3421 gaaattcaaa aaatatgctt gtagcatcat atccaataag tggtggagga tcttcaacta
     3481 tatctggaca aatagatgtt aaatatctta aaaaagggga ttataaagct atattgaaag
     3541 gtacaggtac aacaggaggc ggagtcttag tagtaaaatc tggtctagtt cagatgttta
     3601 caatttaata ttataagtaa aataaaaatc atgaatttat tgggggatag tcacaataca
     3661 tattatttac agatattcat aactattata gttaaagaca ttctattata aagaaaatgt
     3721 ataatttaaa attataataa aaaaaattat cattagtgtc caaaaatcac ttcttcattc
     3781 gttatataag ttatataaat agaaaacaaa tgaagaggtg attttatgaa tcttagaaaa
     3841 acggttataa gtggtatgtg tgctttagta tgttcatcag cagttgcaat acctgcattt
     3901 gctgatgaat atcaagataa gaatattgaa caatattcag cagtaaacta tatagatgat
     3961 actatggtga aaatgtctta tattaagtct ggtacttgca atttaagtat ttcaggaagt
     4021 acagctaaag taacatgctt tgttagagga gcatcaaatg ttacaagcac atcaattatt
     4081 gctagattac agaaaagcaa tgataatggg aaaacatggt caacaatcca aacatggaat
     4141 gcttcaggaa atatttcatg ttctctttct aagtcaaaaa ctataggaaa aggatattac
     4201 agagttcatt ccacaataaa agctaactct gaaagtaaaa atataataag tagtacaaag
     4261 aaatattaaa aatagatatt gtatttatga gttgtagtaa acaagaataa tagtttttta
     4321 aaagcaaata taattaattt taaatagagt gccaatataa aataggtgta taacatttat
     4381 acttttttat attggcactc tattttataa aataagttat tatagaaaat gaaacataat
     4441 ttatatataa attttctgtt tgacctggta tataatcttt tatatcacat atcagtattt
     4501 tcccatcatt ataaccccaa ccaatcacag ttgcaggtat catatcagct tctccatcat
     4561 aaatgattgt atgtttatac atgatttttc cctcgctatt atctatagtt ttattcaaaa
     4621 taccttctgc tattaattta gcaactatgt ctttaatagt ctgtatctgc tttactgtct
     4681 acaaaacata cttcaattaa tatcgctgga gcttttgtat gactaagcca atacaattcc
     4741 cttacgtccg attttgcacc tctattttca gcagatttat atatatcttc agtcaattta
     4801 gttataatct tttgattcat ctaataaaat ctctccctct gaaactattt cctgttcttt
     4861 tttagccttt tccatttctg cgtgaggatt atcaataaaa cttagttgag ataatccggt
     4921 ttcagtagat aatttatctc caagttgact taatatattt gctacaacta aatcattatg
     4981 tggtatctta ggggtaaatt tagccttaat atctttataa tcatagtcaa aaccatattt
     5041 tttattaagc caaatgcaca ataatttgta cctattaaat aaagtatctg caatactatc
     5101 attattttgg ctacaaatcc attctgtact gattaatctt gctacaactg ctaaacttga
     5161 tgtattactt tgcatttttt cattgtgatt tatatgagat gtaatttcat acatgttttc
     5221 ttttattgaa gatagtgtat tttgaacaaa tgtatcattc atgtctttaa taagccattc
     5281 tatttttcca tctccattaa cttgaagtat tccaagttct ttcatccttg gcaaatcatc
     5341 ttctttaata ttacattcag agaaggttaa ataagcattt ctaaaatcac taatttcatt
     5401 acttatatca cttaaattag tttcataagc atcttgtaat ccttttatat cattgaatat
     5461 tgtatctttt cctagttctt cacttctttt acaaattgat attggaacat taccattaaa
     5521 tatattattt actgtaggtt tttctatctc tttaaaattt gaatcaaaat gatatatgta
     5581 ttctttatca tatacatcta tataaatatc atctttaaaa tcttttttaa attctctaaa
     5641 aaaatagatg atctctccat cttcattttc ataatggcag ccatctgttg gttttattat
     5701 tcttactttc atttcattgt tttttacata gtaaagttca tagcaaaatc caaataatag
     5761 tgtatatctc aataaatctg aatcatgctt tttactccaa tggcaagtat agtattctaa
     5821 atcatttata atcttctcat cacctaatct acttgtatag gtgattttat ttgcaagaga
     5881 ataagcgacc tcttcattaa taaacttttt taagaaatta gtgtttatct tattattaga
     5941 cctcttggta accattttat agttactaat agcatctgtt tcacctttat aatacttata
     6001 catagtgttg tattcttgct tttttaaact ctagccttca tatatttctc ttaataaact
     6061 taaatctatt tccatttaat gcatcacctc catacaatca aagacctaaa tttcttctat
     6121 ctaatagtgt aatactttca tttactttaa tattaaaaat cctatttata aattctgctg
     6181 atatatctgg tgcatcatca tgtagagagt acttttgtcc tgtaaaatta aggatttgct
     6241 gtataaatgc cttatcctct tctgcaaaaa tcatttgacc tttatttaaa acaggtatta
     6301 aagtagagat tttatcatct ttatttttct tttggtgctc attaatgatt tctatatctc
     6361 tgtagtaaag aacatcatca ttttttattt taagttctaa ttgattagca gctgtaccat
     6421 taaatgtatt tttttctata taaacatgtg ttatatctgg atacactttt aataaataaa
     6481 tcatatgcaa tatatattta tcaaaatcag ttctagcatt tattttggct agttctgcca
     6541 atctgccaca tagtaaacca ttttctgatt cacttccaac aagaaaagca ctatagtcat
     6601 gtttagaacc acctgcagat gctgggtcac ataataacat tgtctttttg aatgtatgag
     6661 tttctataca ttctctagat taagttctga ttgttttaaa ccatttctca cctattgaat
     6721 ttacatcatt ttgtacctct tgtttaaaag atgttgggtt ttcgtaataa cttaaagcca
     6781 tgtctaaaca attccaaaaa cttggccata atataggaaa tttaatttct ttttcatttt
     6841 cccagtaaaa ttctttagca tcttcaagat gatttgtgtt tttgaaatca aataacaact
     6901 ctttgaaatt aagccataaa ccagaattaa ataattcatc tacattatca actaaaactc
     6961 ctttttcaca tttaaatttc caagttggta aattctttag cctactatag aaacattctt
     7021 tatgttgtaa ggttcctaat gctataaaag ttgttcctct ttttataatc ttaccatttc
     7081 ttattactgg tttttaagca gcatatttta catcatcaga aaatctttta aattttttct
     7141 ctctagcatc ttctgttcta acattttctt ctgactgata atcatcaagt atgataagat
     7201 ctggacgatt attattgtat ttttttcctc tcattggtga tgaagatgat attgcttcaa
     7261 taaaggtttt attagttaat tctaattgag tactattgca aatatatttt ctatcattat
     7321 catttaagag aactccaaat gcttttttaa tatactcatt ttcaagtaat gcatttttta
     7381 tatcttttac gaatttttct gctgtagagc ctatatcaga gtaaatcaaa gtatatgtct
     7441 tatgtttata acaatgtgac catacagttg ttgctaaatc tccaaatgca cttttacctg
     7501 ttcctcttgg ataaattctt cctaattgct gtgaaccatc tccaattata gactcttgta
     7561 tatcttccca taactcatga tgaactttag ctataggagt agcaacatta tcttcttttg
     7621 gtaaatatgt gtcttgtata aaatacatac agaaaaattc taaatttatt tttccaagct
     7681 gataagctag gccattaact ccccaaagat tgcttgaatt agtttttata atctcatttg
     7741 cttctttttc agcttctctt atagttgctc catttcttat aaaggtcttt gccatataac
     7801 taaatattaa ttgtatattt ctttctaaat tatccactcg tatttacttc ctcttaattc
     7861 ttctattttt ttaggttcag tgagtaatac aattaataaa ataaacaatg caaatttttt
     7921 tctaataaaa tcaccctctt tgaaatatgt ctctggtttt taatttttgc tagaaaattt
     7981 ctagaactca ttttctataa ataatacttt tttgaaatag aaggataccc cctatactga
     8041 aaaacagtta tttataatta ttttaaacat aattaaaggg cataattcta tgaatttgcc
     8101 ccactaaaat taacttaagc atatatattg ctcttcttag ttactctcat ggctctttat
     8161 taatctatct aatgttggtc tacttactcc caattcttta gccaattgag tcttattaag
     8221 ttctctagtt ttatatctat cataataact accaaagttg tctatcttaa cttctttacg
     8281 tcctttatat ttaccctgtt ctttagctat agagatacct tctcgttgtc tttctaacat
     8341 gtttgttctc tcaaattcat atattgcgcc aagcattgta agcataagtt ttcctgtagg
     8401 tgtacttgta tctaaatttt ctttatcact aattaacttt acatgtttct tttctaagag
     8461 ctcaactatt tctaataagt ctttagtact tctagcaagt ctactaaagt catgtacaat
     8521 tattgtatct ccttctctta caaaatctaa cattgcgttt agttttgatc ttttagtatc
     8581 tttggcactt attttctcct gatacatttt ttctacatta tgctttttca ttgtaactaa
     8641 ttgtctatct tcattttgtt ctgctgttga aactctcata taacctacta ccatctttga
     8701 tacctccacc tatgtttact ctataaataa tattatagca taaatgtaaa actagagtta
     8761 aagatttgcc atgctttttg taaattaatt ggagttttga ttttattttt acatcagaat
     8821 agatagtttg taatgtaaat ttgtaccagc atactttaca atatgctctt aggaaagata
     8881 tttcttgttt atagattata atatttctct agtatcttta tttttataat ttcaaaaata
     8941 aaaattaaaa ttacagttat tatcatattt cgtgtactat tttctataat attataacta
     9001 aacaatgcaa aaacaatgat taataaaatt acgtttatag tgccagaaat caagaatgat
     9061 tttttcttat tattcatata tttcctccta gttatttgct agttttatac catctcctac
     9121 tctttcagta tatacaactt ttttaaagtt agatgagcta taaaaatatg taacatattc
     9181 atatctgtat ggaacaggaa cattagcatg actgtttcta atatcagtta tttgtctcct
     9241 atagtatgtt tttgtatata cgcctccata tttagtaatg tcatatactt tttctctata
     9301 aatactctca gctaaaccta ataaaaaaga tgaccctcca gaaagataac ctaatcccca
     9361 ttgaatagtt tgtataattc tttctcttgt ataaggagaa cttaatttgc gtgatttttg
     9421 acctagatat ttaacatttt tccaactacc aggtgtaact tttgttgaaa cataagtgtt
     9481 attgcctttt ttatccacaa tcatttcatt ttcattgcta ttaataatag taaattcgtt
     9541 ttcattaaca agttcttgtt tatattcatt ttcttcaaaa gtagatgcat aaaccaaatt
     9601 atatccacta gataaaacaa atattcctgc cattaaaaaa cttattattt ttttctttaa
     9661 cataatattt tactaccttt acttaaatat ttattctaca aacactgtca tataacctgt
     9721 tagttatatt aaaaataatc tttttatata acttcacaat caaaccttgt cttatttcat
     9781 aatagtttta tttaatatca tataatttag acctccttat aagattattt atatatataa
     9841 cgaataataa aagtaatttt ggacaaaata aaaatctttt tattttaaga atgaaacatt
     9901 taaccctcta agaaaactca attaagagcg attcatagag ggcttattat tatattatat
     9961 aactttatat actttttatt tttatatgct tcaatttaac ttatttcaag catattcaag
    10021 tacttctcat taactttata tacatccttt tctctagata aaatctctat ttcttcaaga
    10081 ttattaaaca cttccatcaa ctggtcaact aattcgattt cttttattcc agcctttaag
    10141 tatctacctt tattcttttt gatatagttc tctaatgtca tagaataatt atctttacta
    10201 cagatatatt ttaatatatg ttcttctgtt gctgatagag ttatatcatt ttcaaataat
    10261 tcctctttta atatactctc taaagacttc ctatcatgca tatcacgcat ttcattgata
    10321 gattgtatta tagactttag catgaactct ataaatacag ttaaattata tcctttattc
    10381 tctacatcta gtatagcctt ataatactta gttctgtttt tagatattat atatgatatt
    10441 gaaaactctt taaaagtatc atatccttta ttaattaaat atagatatga taaggctctt
    10501 gatgttcttc cattaccatc actaaaagga tgaacatata caaagtaaaa atgaattatt
    10561 gtactcttta ctaaatcatt tactttacta ttttccataa aaattattaa ttcatccata
    10621 aagttatata ttttcaaagg atcaagtcct gtatgtataa tctcaccttt tgaatcacat
    10681 acatatactt tttcagttct atattcatat tcttctgaat ctaaacagtt ttcacccaat
    10741 atatgatgta aattatatat aaatttgtga ctatataatt tatctaaatt atctaatcca
    10801 tattctaagg ctctatgatt attgtaaatc atatactcac ttttattact tggtttcatc
    10861 tttcctctaa ttatagattt tgcaatcttt ctagttgaaa aggcaccttc tattacacta
    10921 gaataataag actctaaggc taaatcattt ttatcttcta ttattttaaa tatcttgctt
    10981 gatgttaatc tatctatttc atcttttgaa tttaatatgt tatcagtttc atgatagtat
    11041 agttctttat tatcaaaact ctttaaggaa agtataattt tatctccagt agagtattta
    11101 tttttgtatt cttctattgt cagtttaatc accaccttag tttatcttta tctattaata
    11161 ttaacaaaaa gtattagttt ttacactatt tttgattgtt tattttatat attatgattc
    11221 tactcttgat aattaaatct tacttaaaaa ttaattcttg ataattaata aaaaaattta
    11281 tatataagtg tctaaaaaac gattctttat tcgttatata tataaataat actagaaagg
    11341 gaggattata ttatgatatt tagtaaacgc tcttttagaa aaaaacggtg ataaacttgt
    11401 tttaaatttt agtagaatat gatttttgtt ttggcaagta ttaatacata tattaaagag
    11461 ggaggtttaa tatgttaaat aaaaaaaata taagttcaat tattatgaca atgattttaa
    11521 gcttatcaac tactgtattt gttttcgctg atgaaaatac taatgtgaaa ggacaagata
    11581 taaccaaata taatgaagaa atggtctcta aaaacttaga agatttaagt atagaacaat
    11641 taatagatat tagagataaa gctattgata aaaatttaga aggtcttaga aaatttggag
    11701 aagattcagt gaaagaacgt aaagattcaa ttttaaactt tgaatttgga ttagtagctt
    11761 ttgttaacaa aaattatagt aacttaacag aaaaagagaa attaataaga caaatcaata
    11821 ttgttgagta tgaaaattct ataaatgata taatggatcc ttcaggcgat tttttcaaag
    11881 taacaaacca aagttatcag attaatgaat ttgtattaaa aaatggaaaa aactataaag
    11941 agtggtcgta tgaatatgta gagtttttga ttgagcattt agaggattta tgtaattttg
    12001 tagattttga tgcaaaatat gtaatagaaa tgcttgatcc ttcaataaaa ccagatcttt
    12061 cagataatca aaagaaatct ctaaataatg aattaataaa aatgtattca agtaatactc
    12121 taagtacaaa tataaaagat gaaatagaaa actgggaaaa taatttaaat attaatgaga
    12181 aaaattcaaa tgaaccttta ccaagagtaa gcccttctag ttatagacaa caagcattag
    12241 cttatgctaa aaaacatggc tatactaatg gttattatgg tagtacaaat agaaaaaata
    12301 atgcaccttc tccatattat aattttcaaa aagatggata tggagattgt gctaactttg
    12361 tttcacaatg cttacatgaa gctggagtaa cattctggac gaataataat ccatggtatt
    12421 attattctac tagtaataga tcaccttctt gggctggagc aagagaattt aaaatacatt
    12481 ggatgaatcg aattgcatat caaacactta ctgtatcaaa ctctttaagt tttttaagac
    12541 cagcaacacc tgtaagtata ttgaatagta gtggagtagc aactcataca ctaatatcta
    12601 cagataagca ttcaaatgga tataattttt catatgctgc acattcagat gaaggtgcaa
    12661 gaacaaattt gttaaaaaaa cttgaaggaa agaaaatttc ttattacaaa gtttattggg
    12721 aataaataaa aatttatact tttaattaaa tgaaaattga aaagaataaa tatctatttc
    12781 aagatccaat aagtatttag ttgaagcagc tattaaattt tattacataa tcataaaaaa
    12841 gagactagtg gaatttagtc tcttttttat gatttaaaaa tttaataaaa gaattatata
    12901 aatttgtcta aaaattagtt tatcattcgt tataattata taaactatat caaaaaagtg
    12961 ttctattgta ttctttagaa taatcagtaa taaaggttat tctaataaac tgagttattt
    13021 tttcacaaat aaaatactta ttaaaaagga gatttgatat gttaaacaaa aaaaatgtaa
    13081 gtttaattgt tttagtaata gttttaagtt tattcactgc tatatttgtt ttcaataata
    13141 gaaatacaaa tgataaatca aaagaaattg ctaaaaataa tgaagaaata gtgcctaaaa
    13201 acttagaagc tttaagtata gaacaattaa caaaaattag agataaggct attgataaaa
    13261 atttagaagg tcttagagaa tttggagaag attcagtaaa acagcgtaaa gattcaattt
    13321 taaattttga atttggatta gttgcttttg ttaacaaaaa ttatagtaac ttaacagaaa
    13381 aagagaaatt aataagacaa attaatattg ttaactatga aaactctata aatgacataa
    13441 tggatccttc aggttcattc tttgaattag caaatcaaag ttatgaaatt aatgagttca
    13501 tgttaaaaaa caaaaaaaat tataaagaat ggtcatatga atatatagaa ttcttaattg
    13561 atcatttaga tgaattatgc aaatttgttg attttgatat aaaagatgta atagatatta
    13621 ttgatcctac aataaaaaca gatctttcag aagaacaaaa gaaatctttg aatgataaat
    13681 taaagaaagt gtcttcaagt gatactttaa gtgaagacat taagaaggag ataaaaaact
    13741 gggaaaacaa tttgaatagt ttaaatatga ataaaaataa ttctaattaa ctgatagtgt
    13801 aaaatgtaca taattataaa taaaataggg atgtcttaaa attgattatt ttctaatcta
    13861 aatattttag gcctatctaa aaacataaga ttatggtcta aaatttgaaa ttttagacca
    13921 tgctttattt ttacaata
//
LOCUS       DACTZW010000103        13778 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.104, whole genome shotgun sequence.
ACCESSION   DACTZW010000103 DACTZW010000000
VERSION     DACTZW010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13778
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.104"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(<1..874)
                     /gene="speB"
                     /locus_tag="JAM15_16485"
     CDS             complement(<1..874)
                     /gene="speB"
                     /locus_tag="JAM15_16485"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HAT6799848.1"
                     /translation="MKNNFYHMNTFMSMDKNYEESNLIVFGVGFDGTTSNRPGARFAS
                     SSMRKEFYGLETYSPFLDLDLEDYNICDYGDLEISVGSTEQVLKEIYQETYKIVRDSK
                     VPFMIGGEHLVTLPAFKAVHEKYNDIYVIHFDAHTDLREEYNNSKNSHATVIKRIWDI
                     VGDNKIFQFGIRSGTKEEFKFATEEKHTYMEIGGIDTFENIVNMLNGKNIYLTIDLDV
                     LDASVFPGTGTPEPGGVNYREFQEIFKIIKNSNINIVGCDIVELSPDYDTTGVSTVIA
                     CKILRELCLIISDKI"
     gene            complement(864..1715)
                     /gene="speE"
                     /locus_tag="JAM15_16490"
     CDS             complement(864..1715)
                     /gene="speE"
                     /locus_tag="JAM15_16490"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HAT6799849.1"
                     /translation="MELWYTEEWTENVRFSIKVNKHLFEGKSQFQRIDVFDSDEFGKF
                     LTIDGLMMVTYKDEFIYHEMITHVPMATNLNIKKVLVIGGGDGGTVRELSRYPQIEKI
                     DMVEIDKMVVDVSKEYMDICSCKLDDKRVSLYFEDGVNFVKCAHDKSYDLIIVDSTDP
                     IGPGEGLFSTNFYKDCYRILTDDGILVNQSESPYFDFNAKEMKRANKKLKQIFPISEV
                     YQAHIPTYPSGHWLFGFASKKLNPVKNQDRNGWEKLSLKTKYYNSDIHLGSFMLPQYV
                     KEMLDEE"
     gene            complement(1745..2158)
                     /gene="speD"
                     /locus_tag="JAM15_16495"
     CDS             complement(1745..2158)
                     /gene="speD"
                     /locus_tag="JAM15_16495"
                     /EC_number="4.1.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine decarboxylase"
                     /protein_id="HAT6799850.1"
                     /translation="MKFETLGRHILVEYYNCDENVLKDPRLIENFMNDSALNAKATIV
                     DSVFHHFNPWGVSGAVIIAESHLTIHTWPEYGYAAADFFTCGDIDPWKSFELLEQLLK
                     SERSESTEIPRGLTTKIKKYSKKDLGKITHKPEAV"
     gene            complement(2245..3720)
                     /locus_tag="JAM15_16500"
     CDS             complement(2245..3720)
                     /locus_tag="JAM15_16500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HAT6799851.1"
                     /translation="MDSEFANAVELSYECAPLLESLKEYSEKDIACFDVPGHVKNRGV
                     AILNKYLGESLMKMDINSSPTMDNVSAPNGIIKNAQDLLAQAYMADEAFFITNGTTQA
                     IHAMILSVIKPGEKVLLPRNIHKSVINALILCGGIPIFIQPEFDEKLGISLNITLEKV
                     RTEIEKDCNIKALFFLNPTYYGVCADLESIIELCHKNNVLVLVDEAHGAHFPFHLDLP
                     PSAISLGADMVAVSIHKTGGALTQSSALLLNRDNVSFEKVLQSINMLQSTSASYLLMA
                     SIDGARVNLVENGEKQLSKALNLSRYAKSKLNKIDGIKVLSTEILKQKGVKFIDETKL
                     CINVKELNLTGFEVYDLLYKNFSIQVELGDSYNILALVSIGTNKSDIDRLVKALSIIA
                     KIYRKESTLNEFNMVQINPIIKLNPREAFYAPKESVEINSCIDRICGESIMAYPPGIP
                     IIAPGELITEEIMEYIIFLKNSNAYLTDVQDKNLDRILVIK"
     gene            complement(4358..5011)
                     /locus_tag="JAM15_16505"
     CDS             complement(4358..5011)
                     /locus_tag="JAM15_16505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAT6799852.1"
                     /translation="MKVDPLTTQVYDYISKKIQNGEYEANQRITESEICKSIGVSRTP
                     AREALTRLAGENLLEKIPNKGFVVKEFQEKEKLDTYSVIGVLDALAGSSALQNLTESD
                     LVKMEELTEMMAVSIKYKNYNSYLKLSNEFHDIYITKSDNQVLVNLLNSLRYNFMSKS
                     YTSDNEDELYKMLTYSNNQHIEVVKFMRENDLENVERVLREHWKTIPIAEMKKEKLL"
     gene            complement(5256..7121)
                     /locus_tag="JAM15_16510"
     CDS             complement(5256..7121)
                     /locus_tag="JAM15_16510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HAT6799853.1"
                     /translation="MQSVIEYNSWDKNFKAPFGALKFDEELTICVKVKEGYNIKSISL
                     EINREEEMRTITLNEELDNDKLGKCFCGKIEKFDGTGVYFYYFKVDVEMDGQIKTLFY
                     GKNRDNGYSCEYNYSDINKYQITVYKDFKVPTWYKEGILYHIFVDRFNNGNRSGKVDN
                     PKKNSFIYGNWEDIPMYIKDSQGDVIRWDFHGGNLRGIINKLGYLKKLGVSILYLSPI
                     FEASSNHKYDTGDYKKIDPMFGDEDTFKELIDKAKEKGISIVLDGVFSHTGADSKYFN
                     MYGNYNSLGAYQSKESPYYSWYMFEEFPQKYKSWWDVKTLPNINELEHSYMDYIIYDN
                     DSVINKWVNMGVKGWRLDVADELPTKFIRELKKELKNADEDSILIGEVWEDASNKISY
                     GQRRSYLLGEELDSVMGYPFRNNMFSFLKGEINSYELCNRYMQIKENYPKESFRSNLN
                     LIGTHDVTRAKTELNDDVDLVKLAVAIQMTFEGVPYIYYGDEAGLCGGVDPDNRRTYP
                     WKNEDEDMLNFYRDVIKIRNKNKLLSSGNTEFIYTNNDSVFSFIRVDANNDRMLILVN
                     RSENVESISLCIESSFIEEIPIKYSLKNANSTIQIENNELKVDLDSKSFRIFRVN"
     gene            complement(7126..9546)
                     /locus_tag="JAM15_16515"
     CDS             complement(7126..9546)
                     /locus_tag="JAM15_16515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HAT6799854.1"
                     /translation="MVTISKKKFKQKFEVKMYSLYAQSIKEATDEQLLNVLCSLLKDE
                     IAKKWVATKLDKKKEVYYFSLEFLIGRQLKSNLLNLNIEEEVREGLSELGINLDDLIE
                     AEVDPALGNGGLGRLAACFLDSMASLNISGQGYGIRYKYGLFEQKFVNGYQVEVPDNW
                     LTEGRYAWEIVRPNEATMVKFGGEVELIKEGSHLKVIHKNYLPVMAMPYDIPIIGYQN
                     QCINTLRLFKSEIPKRDFGELTSNALNYSGSYEEALKHKYYTEEISQVLYPDDSNYAG
                     KLLRLKQEYFFVSAGIQDIIRKYKKNKLNIDNLFDKVAIHINDTHPTLCIPELMRILL
                     DEENLSWDEAWEITKKTVSYTNHTIMSEAMEKWSVSMMKELLPRIYMIIEEINRRYVE
                     ELNNKGYEQDRIKRMSIIDCDNINMANLCIVTSHSVNGVAKLHTHILETEVLKDFYQD
                     EPNKFNNKTNGIAHRRWLISSNPQLSNLITDLIGDSWKKDTLQLKNIEKFKNDSSVLQ
                     RLDDIKYNNKANLAKFIKDKYDLNVDPSSIFDVQVKRLHAYKRQLLNIFNVLHMYHEL
                     LDNPNLNLDPRTFIFGAKAAPGYYLAKCIIKFINSVASTINNDVRVKDKLKVVFLENY
                     GVSLAEIIIPAANVSEQISTTTKEASGTSNMKFMMNGAITLATLDGANVEICEQVGKE
                     NMFLFGLSAEQVLNYNKYGGYSSLDLYHSNMDIKRVVDDLINGFIPNLGEEGRSIYNS
                     LTTYNDEYFVLRDFENYGQAQADINRLYRDKEKWNKMSLVNIANSGFFSSDRTISEYA
                     KDIWFKRV"
     gene            complement(9560..11002)
                     /gene="glgA"
                     /locus_tag="JAM15_16520"
     CDS             complement(9560..11002)
                     /gene="glgA"
                     /locus_tag="JAM15_16520"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HAT6799855.1"
                     /translation="MKVFYVTAECWPFAKTGGLGDVSYALPKELKKEGVDVRVIMPKY
                     STIPSYLKDQLKEIAVFSVRVGWRNQYCGLLEMELDGVKFYFIDNEFYFRREDERKSI
                     YGYGDDAERYTFFTDAVLEAISRIDFYPDVIHINDWHTGMLPLILKERYATLEGYKNI
                     KTMYTIHNLQYQGVFDKHVLYDILDLPQKYFDNGDIEYYGSINFMKAGINFADKIITV
                     SPTYANEIQTSFYGEQLDGLLRKESGKLKGILNGIDYDLNDPVKDKDIFVHYDVDSID
                     KKVENKLRLQDILGLKKDSSIPLIGIVSRLVSQKGFDLIAYMMPELMREDLQIVVLGT
                     GEHQYQSMFNYYDSNFSDKVSARITFNASLAQQIYAASDMFLMPSLFEPCGIGQMLAM
                     RYGSLPVVRETGGLRDTVIPYNKFTGEGNGFSFKNYNAHEMFFCLKNAIKVFKDKEKW
                     IKLVENAMKTDNSWKKSAKEYIETYRDICD"
     gene            complement(11031..12161)
                     /gene="glgD"
                     /locus_tag="JAM15_16525"
     CDS             complement(11031..12161)
                     /gene="glgD"
                     /locus_tag="JAM15_16525"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HAT6799856.1"
                     /translation="MRNECLGIINLNKKGDPAINKLNYGRPIASTPIAGRYRIIDFAL
                     SNMINSGITKVGIFAKEKYRSLTDHIGSGKDWDLSRKKGGLSIFSPENTKYRNTYSHR
                     EGDIYTILANLDYIEKSEEEYILIAPSYMLCNLNYSQALEYHKKSHNDITIIYKNVNN
                     ANKDFAGNLTLNLDSNNRVINVGNNLGKFPRANICMETYIMKREDFVECIYNIVNKGS
                     YCYLEEFIIEEAENMKIGAYEYTGYLKCVNSVESYFEMSKDLLNLEVADELLYSERKI
                     FTKEKNESPTIYTDSAKVENSFIASGCLIEGTVKDSIIFRKVNVEKGTVIENSIVMQN
                     CVIKSNAKLYNAILDKNTSVSNGKELRGDEKYPLVVEKNTNI"
     gene            complement(12163..13323)
                     /locus_tag="JAM15_16530"
     CDS             complement(12163..13323)
                     /locus_tag="JAM15_16530"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HAT6799857.1"
                     /translation="MKKEMLAMILAGGQGSRLGVFTKRIAKPAVSFGGKYRIIDFVLS
                     NCSNSGIDTVGVLTQYRPLILNSHIGMGSHWDLDRINGGVYVLQPFMNEKEGNWYNGT
                     AHAIYQNMDFVDTYNPEYVLILSGDHIYKMDYSKMLKFHKEKGSKATIAVIEVPWDEA
                     SRFGIMNTNEDSSIYEFEEKPSEPKSNLASMGVYIFDWKMLRNYFKEAEKNPEINYDD
                     FGKNLIPKMLEDNVGMYAYPFKGYWRDVGTIQSLWDANMDIIKSPETLDLADPKWKIY
                     TNTMAMPPQYIGKNANVHRSMIADGCRILGEVGNSVLSHGVVVGKGSKVIDSVIMPNV
                     VIGENVTIEKAMIGECATINDNVQIKNVNNEINVVSEYENIEPRCVLIEGGL"
BASE COUNT         4358 a         2476 c         1374 g         5570 t
ORIGIN      
        1 taattttatc agatattatt aagcataact ctcttaagat tttacaagct ataactgtcg
       61 atacacctgt tgtatcgtaa tcagggctta actctacaat atcacaacca actatattta
      121 tattagagtt ttttataatc ttaaaaatct cttgaaactc tctataattt acaccaccag
      181 gttctggtgt acctgttccc ggaaacacag atgcatccaa tacatctaaa tctatagtta
      241 gataaatatt ctttccattt agcatattaa ctatattttc aaacgtatct attcctccta
      301 tttccatgta tgtgtgtttt tcttctgtag caaatttaaa ttcttctttt gtcccagacc
      361 ttataccaaa ttgaaatatt ttattatcac ctacaatatc ccatattctt ttaattactg
      421 ttgcatgaga atttttacta ttattatatt cttccctcaa atcagtatgg gcatcaaaat
      481 gaattacata tatatcattg tacttttcat gtactgcttt aaaggctggt aatgtaacta
      541 aatgctctcc tccaatcata aagggtacct ttgaatctct aacaatctta tatgtctctt
      601 gatagatttc ttttaagact tgttctgtac ttccaacact aatttctaaa tctccataat
      661 cacatatatt ataatcctct aagtccaaat ctaaaaaagg actatatgtc tcaagaccgt
      721 aaaattcttt tctcatagag ctacttgcaa atctagcccc aggtctgtta gaagtagttc
      781 catcaaatcc aacaccaaat actataagat tagattcttc ataatttttg tccatactca
      841 taaaagtgtt catatgatag aaattattct tcatctagca tctccttcac gtattgaggt
      901 aacataaacg aacctaaatg tatatcacta ttataatatt tagtttttaa acttaatttc
      961 tcccatccat ttctatcttg attttttact ggattaagtt tttttgaagc aaatccaaac
     1021 aaccagtgac cagatggata tgttggtata tgtgcttgat aaacttctga tattggaaat
     1081 atctgtttta attttttatt agctcttttc atctctttag cattaaagtc aaaatacgga
     1141 ctttcacttt gatttactaa aattccatca tcagtcagta ttctataaca atccttataa
     1201 aaattagttg agaaaagccc ttcgcccggt cctattgggt cagttgaatc tactattatc
     1261 aggtcatatg atttatcatg tgcacactta acaaaattaa caccatcttc aaaatataaa
     1321 ctcactcttt tatcatctaa tttacatgag catatatcca tatactcctt agatacatct
     1381 acaaccattt tatctatttc aaccatgtca atcttttcta tttgaggata acggcttaat
     1441 tctcttactg tacctccatc acctccacct atgactaata ctttctttat gtttaaattt
     1501 gtagccatag gaacatgagt tatcatctca tggtatataa attcatcttt atatgttacc
     1561 atcattaatc catctattgt tagaaatttt ccaaattcat cactatcaaa tacatctatc
     1621 ctttgaaatt gagactttcc ttcaaataga tgtttattta cttttataga aaatcttaca
     1681 ttttctgtcc attcttctgt ataccaaagt tccatataat aatcctcact ttctcttgta
     1741 tgttttatac tgcttctggt ttatgagtaa tcttacctaa atcttttttt gaatattttt
     1801 taatttttgt agttaagcct cttggaattt ctgtagactc gcttctttca gactttaaaa
     1861 gttgctctaa taattcaaaa cttttccatg ggtctatatc accacaagta aaaaaatctg
     1921 ctgctgcata accatattca ggccatgtat gtattgtcaa atgagattca gcaattataa
     1981 cagctcctga aaccccccaa ggattaaaat ggtggaatac agaatccaca attgtcgctt
     2041 ttgcatttaa tgctgaatca ttcataaaat tttctataag acgtgggtct ttaagtacgt
     2101 tttcatcaca attatagtat tctactagta tatgtcttcc tagtgtttca aatttcattt
     2161 caaccccaac tcctttatac ttttaataag ttctatttga taaactctac ttaacaaaca
     2221 cttgcccttg caaaataaag taatttattt tattactagt attctatcta agtttttatc
     2281 ttgtacatca gtaagatacg cattgctatt ttttaagaaa ataatatact ccataatttc
     2341 ttctgttatc aattctcctg gagcaataat cggtatacct ggtggatatg ccattattga
     2401 ttctccacaa attctatcta tacatgaatt gatttctaca ctttcctttg gtgcataaaa
     2461 agcttctctt ggattaagtt taataattgg atttatttga accatattaa attcatttaa
     2521 tgttgattct tttctataaa tctttgcaat tatagaaagt gcttttacta atctatctat
     2581 atctgattta tttgttccaa tggacacaag tgccagtata ttatatgaat ctcccaattc
     2641 tacttgaatt gaaaaatttt tatataataa atcgtatact tcaaatccag tcaaatttaa
     2701 ttcttttaca tttatacaca attttgtttc atctataaat ttaacacctt tttgtttcaa
     2761 tatttctgta gataaaactt ttattccatc aattttgttc aatttagatt ttgcatacct
     2821 agatagattt aatgcttttg acagttgctt ttcaccattc tcaactagat taactctagc
     2881 accatctata cttgccataa gcaaataaga tgctgatgtt gattgtagca tattgattga
     2941 ttgaagaacc ttttcaaaac ttacattatc tctattcaat aagagtgctg aagattgtgt
     3001 caatgctcct ccagttttat gtatacttac agctaccatg tcagctccca aacttattgc
     3061 agaaggaggt aaatctaaat gaaatggaaa atgtgcacca tgagcttcat caactaacac
     3121 taaaacatta tttttatggc atagttctat aatactctca aggtctgcac aaactccata
     3181 gtaagttgga ttaaggaaaa ataatgcttt tatattacaa tctttttcta tctctgttct
     3241 aactttttca agagtaatat ttaaacttat acctagtttt tcatcaaatt ctggctgtat
     3301 aaatattggt attcctccac aaagtattaa cgcatttatt actgatttat gtatatttct
     3361 tggaagtaat actttttcac ctggttttat aacactcaaa atcattgcat gtattgcttg
     3421 agttgtgcca ttcgttataa agaatgcctc atcagccata tatgcttgtg ctagcaaatc
     3481 ttgtgcattt tttataatcc catttggcgc agatacatta tccatagttg gtgatgaatt
     3541 tatatccatt ttcatgagac tttcacctag atatttattt aatatagcta cacctctatt
     3601 ttttacatgt ccaggaacat caaaacaagc tatatctttc tctgagtatt cctttaacga
     3661 ctctaataat ggagcacact catagcttaa ttcaactgca tttgcaaact cgctatccat
     3721 gatttcaaat tcatctcctc tctatattca aatattttta atatttatta tttattattt
     3781 ctatttttta tttttacttt tattaaactc atgatattta ttatattaac attccagcat
     3841 ttttacaagt gtttttttga agttactcaa aaacatatac attagttata tcaatattta
     3901 taaacttttt atttttttgt tgtttacatt aattttttta aaacttagta tttataaact
     3961 ttcttatttt ttattatttt gcttttttta cttttttgag ttttagtaag cttttgagtt
     4021 tactattttt aatttataag tattttatta ctaaactttt atattattct tatttcatat
     4081 atcaaaattc ttggtttagt tggactaaat aattttccta tttttgtatt ttaattttaa
     4141 tataaaattt attaaatttt ttaattgata aaataaattc tatatttatg atactaaaat
     4201 tctataagtt cattgattta tatatgttga tttaaatata ttattctatc gtagtgcctt
     4261 agagttttta tttgtattta aagttaaatt tattcttgtt tttcctttaa tatttaatag
     4321 taaaataaca aaattataaa aaaaataaag agaaacttta taaaagcttc tcttttttca
     4381 tctctgctat aggtatcgtt ttccaatgct ctctcaaaac tctttcaaca ttttctaaat
     4441 cattctccct cataaatttt actacttcaa tatgttgatt attgctgtat gtcaacattt
     4501 tatataactc atcttcatta tcactagtat atgactttga cataaaatta tatcttaaag
     4561 agttcaatag atttactaac acctgattat ctgatttagt tatgtatata tcgtgaaatt
     4621 cattacttaa ttttaaatag ctattgtaat ttttatactt tatagagacc gccatcattt
     4681 ctgttaattc ttccattttt actaggtctg attcagttaa attttgtaat gctgaagaac
     4741 cggctaacgc atccaatact ccaattacgg aataggtgtc taatttctcc ttttcctgaa
     4801 attcttttac tacaaatccc ttattaggta ttttttctag taaattttca cctgctaacc
     4861 tagttaatgc ttctctagct ggtgttctac taactccgat agatttacaa atctcagatt
     4921 cagtaattct ctgattagct tcatactctc cattttggat tttctttgat atatagtcat
     4981 atacttgagt tgtaagtgga tctaccttca taagacgttc ctccatatta agattataaa
     5041 agttaaatct ccctacaact ttggtagaga gttcagtttt atcttactaa tttatataat
     5101 atcacaatta tgatattttt tatacttctt tgtaatattt tgaaacacta aaattcttat
     5161 gataatttat acaaaaaaag tagaaaaagt tttgataaaa caaaactctt tctacattca
     5221 ccttattttc tatttatttt tctaaaaaag gatatttaat ttactctaaa aattctaaat
     5281 gatttagagt ctaaatctac tttcaactca ttattttcaa tttgtatagt actatttgca
     5341 tttttaagac tatactttat aggtatttcc tcaataaaac tactctctat acataatgat
     5401 atactttcca cattttcact tctatttact aaaattaaca ttctatcatt atttgcatca
     5461 actctaataa aagaaaatac agaatcatta ttagtatata taaattctgt atttccagaa
     5521 cttaaaagtt tattcttatt tctaattttt ataacatctc tataaaaatt aagcatatct
     5581 tcgtcttcat ttttccatgg ataagttctt ctattatctg ggtcaacacc tccacaaaga
     5641 cctgcttcat ctccataata tatatatggt actccttcaa atgtcatctg tatagctaca
     5701 gcaagcttca ctaaatctac atcatcattt aattccgttt tagctcttgt aacatcatgt
     5761 gttccaatta aatttaaatt agacctaaat gattcttttg gataattttc tttaatctgc
     5821 atatatctat tacaaagttc atatgaatta atttctcctt ttaagaaaga aaacatgtta
     5881 tttctaaaag gataacccat aacagaatct aattcttcac ctaataaata acttcttctc
     5941 tgaccatagc taatcttatt tgatgcatct tcccatactt cacctataag aattgagtcc
     6001 tcatctgcat tttttaattc cttttttaac tctcttataa acttagttgg taattcgtct
     6061 gcaacatcta gtctccagcc cttaacaccc atatttaccc atttatttat aacgctatca
     6121 ttgtcatata ttatataatc catatagcta tgttctaatt catttatatt tggcaatgtc
     6181 ttaacatccc accaactttt atacttttga ggaaattctt caaacatata ccatgaataa
     6241 tatggagatt ctttagattg atatgcccct aaactattat agtttccata catattaaaa
     6301 tatttactat ctgctccagt atgactaaaa actccatcta atactattga tatacctttt
     6361 tcttttgctt tatcaataag ttctttaaat gtatcttcat ccccaaacat tgggtcaatt
     6421 tttttatagt cacctgtgtc atacttatga ttactagagg cttcaaatat agggcttaga
     6481 tatagtatac ttacacctaa tttttttaaa tatccaagtt tattgattat ccctcttaaa
     6541 tttccaccat ggaaatccca tcttataaca tccccttgac tatcctttat gtacataggt
     6601 atatcttccc aatttccata tatgaaacta ttttttttag gattatcaac cttaccacta
     6661 cgatttccat tattgaatct atctacaaat atatgataaa gtattccttc tttgtaccat
     6721 gttggtactt taaaatcttt gtaaacagtg atttgatatt tattaatatc actataatta
     6781 tattcacaag aatatccatt atctctgttt tttccataaa ataaagtctt tatctgacca
     6841 tccatttcaa catcaacttt aaagtaataa aaataaacac ctgtaccatc aaacttttca
     6901 atcttaccac aaaagcactt tccaagttta tcattatcta attcttcatt taaagttatt
     6961 gttctcattt cctcttctct atttatttct agggaaatag acttgatatt gtatccctcc
     7021 tttactttaa cacaaatggt caattcctca tcaaatttta aagctccaaa cggagcctta
     7081 aaatttttat cccaagagtt atattctatt acactttgca tttaatcaca cccttttaaa
     7141 ccaaatgtct tttgcatact cagaaattgt tctatcagaa gaaaaaaatc cagagttagc
     7201 tatattaact aaagacattt tattccattt ttctttatct ctatataacc tgtttatatc
     7261 tgcttgagct tgaccataat tttcaaaatc tctcaataca aaatactcat cattgtaagt
     7321 agtgagtgaa ttataaatac ttcttccttc ttcgccaaga ttaggaataa atccatttat
     7381 taaatcatct actacccttt ttatatccat attagaatga tataggtcaa gtgaagaata
     7441 tccaccatat ttattataat ttagtacttg ttctgcacta agtccaaata aaaacatatt
     7501 ttctttacca acctgttcac atatctctac atttgcgccg tcaagtgtag ccaaagttat
     7561 agcaccattc atcataaact tcatattact tgttccagat gcttccttag ttgtagttga
     7621 aatttgctca ctaacatttg ctgctggtat tattatttct gctaatgata ctccataatt
     7681 ctctaaaaat actactttta acttgtcctt tactctaaca tcattattta tagtacttgc
     7741 aacagaattt ataaatttaa ttatacattt agccaaataa tatcctggtg ctgcttttgc
     7801 gccaaatata aaagttcttg ggtcaagatt caaattagga ttatcaagta attcatgata
     7861 catatgaagt acattaaata tattcagtaa ctgtctttta tacgcatgca atctcttaac
     7921 ttgaacatca aatatcgaac ttgggtctac atttaaatcg tatttatctt ttataaactt
     7981 tgctagattt gctttattat tgtattttat atcatcaagt ctttgtaaaa cagaggaatc
     8041 atttttaaat ttttcaatat tttttaattg taaggtatct ttcttccatg aatcaccaat
     8101 taaatctgta attaaattgc taagttgagg atttgaactt ataagccatc gcctatgtgc
     8161 aattccatta gtcttattat taaatttatt tggttcatct tgatagaaat cttttaatac
     8221 ctctgtttca agaatatgag tatgaagctt agcaactcca tttacactat gacttgtgac
     8281 aatacataag tttgccatat tgatattgtc acagtctatt atactcattc tttttattct
     8341 atcctgctca tatcctttat tatttaattc ctctacatat cttctattta tttcttctat
     8401 tatcatataa attcttggta atagttcttt catcatactt acagaccatt tttccattgc
     8461 ttctgacatt atagtatgat tagtatagga cactgttttt ttagttattt cccatgcttc
     8521 atcccaagat aaattttctt catcaagcaa aattctcata agttctggta tgcataaggt
     8581 aggatgtgta tcatttatat gaattgctac cttatcgaat aaattatcaa tatttaattt
     8641 gttcttttta tattttctta ttatatcttg tatccctgca cttacaaaaa agtattcttg
     8701 tttcaacctc aacaacttac ctgcatagtt tgaatcatca ggatataata cctgtgatat
     8761 ttcctcagta taatacttat gttttaaagc ctcttcatag ctaccagaat aatttagagc
     8821 atttgaggta agttcaccaa aatctctctt tggtatttca ctcttaaaca atcttaaagt
     8881 atttatacat tggttttggt atccgattat tggtatatca taaggcattg ccattacagg
     8941 aaggtagttt ttatgaatta cttttaaatg actaccttcc ttgattaatt ctacctcacc
     9001 accaaacttc accattgttg cttcatttgg tcttacaatt tcccatgcat atcgtccttc
     9061 tgtaagccag ttatcaggca cttctacctg ataaccattt acaaattttt gttcaaacag
     9121 accatattta tatcttattc catatccttg accacttatg ttcaaagatg ccatagaatc
     9181 taaaaagcaa gctgctaatc taccaagtcc accatttcct aaggctgggt ctacttcagc
     9241 ttcaattaaa tcatccaagt tgattcctaa ttcagataaa ccttctctaa cttcttcttc
     9301 aatatttaaa tttaataaat tagattttaa ttgtctccct attaaaaatt ctaaactaaa
     9361 ataataaact tcttttttct tatctaactt tgtagcaacc catttttttg ctatctcatc
     9421 tttcaataga ctacataata catttaacaa ttgttcatca gtagcttcct tgatagattg
     9481 tgcatataag ctatacattt ttacttcaaa tttttgcttg aatttctttt tgcttattgt
     9541 taccaaaaaa accactcctt taatcacata tgtctctata tgtttctata tactccttag
     9601 ctgatttttt ccaactatta tctgttttca ttgcattttc aactaattta atccattttt
     9661 ctttgtcctt aaacactttg attgcatttt tcaaacagaa aaacatctca tgagcattgt
     9721 aatttttaaa actaaatcca ttgccttctc cagtaaattt attataaggt attactgtat
     9781 ccctaagtcc tccagtctct ctaactactg gtaaagaacc atatctcata gctaacattt
     9841 gacctatacc acaaggctca aataatgatg gcattaagaa catatcactt gcagcatata
     9901 tctgttgagc caatgatgca ttaaaagtaa ttctagctga tactttatct gaaaaattag
     9961 aatcataata attgaacatt gattgatatt gatgttctcc agttcctaaa acgacaatct
    10021 gtaagtcttc tctcataagt tctggcatca tgtatgctat taaatcaaat cctttttgag
    10081 aaactaatct cgaaactata cctatcaacg gaatagatga atctttttta agtcccaata
    10141 tatcttgtaa tctcaattta ttttctactt ttttgtcaat tgagtctaca tcataatgaa
    10201 caaatatatc tttatctttt acagggtcat ttaaatcata atctatacca tttaatatac
    10261 cttttaattt tcctgactct tttctaagta atccatctaa ttgttcacca taaaaagatg
    10321 tttgtatttc atttgcataa gtaggactaa cagttataat tttatctgca aaatttatac
    10381 cagctttcat aaaatttatt gagccataat actctatatc tccattatca aagtattttt
    10441 gtggtaagtc caatatatca tataaaacat gcttatcaaa tacaccttga tattggagat
    10501 tatgtatagt atacatagtt tttatatttt tatacccctc aagggttgca tatctttctt
    10561 ttagaattaa tggtaacatc cctgtatgcc aatcatttat atgtattaca tctggataaa
    10621 aatcaattct acttatagct tctaaaactg catctgtaaa gaaagtatat ctttctgcat
    10681 catctccata tccatagata ctctttcttt catcttctct tctaaaataa aattcattat
    10741 ctataaagta aaattttaca ccatccaatt ccatttctaa aagaccacag tattgatttc
    10801 tccatccaac acgtacacta aacacagcta tttcttttag ttgatctttt aaataacttg
    10861 gtatagttga atatttgggc attattaccc ttacatctac accttctttt tttaattctt
    10921 taggcaatgc ataagaaaca tctcctaatc ctccagtttt tgcaaagggc caacactctg
    10981 ctgttacata aaaaaccttc attagtcatt cccccttcta aaaaatttat ttatatattt
    11041 gtattctttt ccactacaag aggatatttt tcatctcctc ttaattcttt cccatttgat
    11101 acactcgtat ttttatctaa tattgcatta tatagttttg catttgactt tattacacaa
    11161 ttttgcatta ctattgagtt ctctataact gttccttttt caacatttac ctttctaaat
    11221 atgatactat cttttacagt accttctatt aaacaaccag atgctataaa gctattttct
    11281 actttagcac tatctgtata aattgtaggt gattcattct tttcttttgt aaatatcttt
    11341 ctttcagagt ataataattc atctgcaact tctaaattta ataaatcttt gctcatttca
    11401 aaatatgatt caacagaatt tacacatttt agatatcctg tatattcata agctcctatt
    11461 ttcatatttt ctgcttcttc aataataaat tcttctaaat aacaataact gcctttattt
    11521 acaatgttat atatacattc aacaaaatct tcacgcttca taatatatgt ctccatacat
    11581 atgtttgctc tagggaattt gcctaaatta tttcctacat ttattaccct attgttacta
    11641 tctaaattta gtgttaagtt accagcaaaa tctttatttg cattatttac atttttatat
    11701 attatagtta tatcattatg agatttttta tggtattcca atgcttgaga ataatttaaa
    11761 ttgcatagca tatagcttgg agctattaaa atatattctt cttcactctt ttctatataa
    11821 tctagattag ctaagatagt atatatatca ccttctctat gtgagtaagt atttctatac
    11881 ttagtgtttt ctggactaaa aattgatagg ccaccttttt ttctacttaa atcccaatct
    11941 ttaccactac ctatatggtc tgtcaatgat ctgtattttt cttttgcgaa tattccaact
    12001 ttagtgattc ctgaatttat catattagat aaagcaaagt ctattattct atatcttcca
    12061 gctattggtg tagatgctat tggtcttcca tagttaagtt tgtttattgc tgggtctcct
    12121 tttttgttta aatttattat ccctaaacat tcatttctca tcttaaagac ctccttctat
    12181 taatacgcat ctaggttcga tattttcata ctcagaaact acatttattt cattatttac
    12241 attctttatc tgaacattat catttatagt tgcacactca cctatcatag ctttttctat
    12301 agttacattt tcacctatta caacatttgg cattattact gaatcaatta ctttacttcc
    12361 tttaccaaca acaactccat gtgataatac agagttgcct acttcaccta aaattctaca
    12421 accatcagct atcattgatc tatgaacatt tgcattttta cctatatatt gtggaggcat
    12481 tgccatagta tttgtatata tcttccattt agggtctgct aaatcaagtg tttctggaga
    12541 ttttattata tccatattag catcccatag actttgtata gttcctacat ctctccagta
    12601 tcctttaaat ggataagcat acattccaac attatcttct aacattttag gtattaaatt
    12661 ttttccaaaa tcatcataat ttatttctgg atttttttct gcttccttaa aataatttct
    12721 caacattttc caatcaaata tgtatactcc catagatgcc aaattgctct taggttcact
    12781 tggtttttct tcaaattcat agatacttga atcttcattt gtattcatta tcccaaatct
    12841 tgaagcttca tcccaaggaa cttcaatcac tgctattgta gctttagagc ctttttcctt
    12901 atgaaatttt aacattttgc tataatccat cttgtatata tggtcaccag ataatatcaa
    12961 tacatattct ggattatagg tatctacaaa gtccatattt tgatatatcg catgtgctgt
    13021 accattatac caattccctt ctttttcatt cataaatggt tgtaaaacat agacaccacc
    13081 atttattctg tccaaatccc aatgacttcc catacctata tgtgaattta atatcaacgg
    13141 tctatattga gttaaaacac ctacagtatc aataccagag tttgaacaat tacttaacac
    13201 aaaatctata attctatact tacctccaaa tgatacagct ggtttggcaa ttctttttgt
    13261 aaaaacacct aatcttgaac cttgccctcc tgccaaaatc atagctaaca tctctttttt
    13321 catttaatga cactcccctc atctagtaat taatatttat aattgcattt ttacttttat
    13381 aaactttatc agtcaataaa tgttgtgtat aaatgttgct taaataatac cttaataaaa
    13441 ataaaataat atcaactata aaattgatat aatgtatacc ccataatgga cttaccgaca
    13501 tatacattat tttccataag tactatagta tttattaata ttcaattatc ggttaaaaaa
    13561 taatacaaat tttattttat aaatataaaa acatttttta tgaatctctt gtgtcataca
    13621 aacatgctta ttttttaatt tgtcaaattt gtgataacaa aatataatct aatatttgtt
    13681 aaataattat ccaaagaaaa ttaagtaaat attaatcaac tttatttttg aattgatatt
    13741 tctttgtcta tcatttaaac aagaggatat aaactttt
//
LOCUS       DACTZW010000104        13757 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.105, whole genome shotgun sequence.
ACCESSION   DACTZW010000104 DACTZW010000000
VERSION     DACTZW010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13757
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.105"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            <1..987
                     /locus_tag="JAM15_16535"
     CDS             <1..987
                     /locus_tag="JAM15_16535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HAT6799858.1"
                     /translation="VSDELDMTSNKTDYISNELYNLSNKSIKDNIPIKMAVITKSNML
                     NQLPDLVELERVFSKIEFKVCFDMFMTDTATLCDMFIPCTNTLESEDIIYSSMTNPYI
                     TYNERAVKPAHKLMDEYYFFMELAKKMGLNDYPFVEKRTYLEKVIEPLKRFDKNLDIE
                     KLKNNYFTIHNLVAWEDKKFETPSGKYELYSESIKNLGINPTPVYISNKYKEIEDKNI
                     SFRLLTNHHADTLFSQHFMDKKSIAQAYINQRMAKKVGIEDKDIVILRSKKAKINVQI
                     NIDDGVGNYIVKMYVGWWKKHGNPNSLTDTGISDFGGQVTYNESMVEIIRQN"
     gene            1075..1410
                     /gene="spoIIAA"
                     /locus_tag="JAM15_16540"
     CDS             1075..1410
                     /gene="spoIIAA"
                     /locus_tag="JAM15_16540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor antagonist"
                     /protein_id="HAT6799859.1"
                     /translation="MVNYSLEHKNLYIEFMCSELDHHVANEIREEIDNLLSVNQVKNV
                     VFNFENINFMDSSGIGVIIGRYKKISNEGGRVSVINISSRVKKIFDLSGLNKIIGIYD
                     TYEEALSSL"
     gene            1424..1852
                     /locus_tag="JAM15_16545"
     CDS             1424..1852
                     /locus_tag="JAM15_16545"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor"
                     /protein_id="HAT6799860.1"
                     /translation="MNNIMEVKFSAISENESLARVIVASFAAKLDPTVDELVDIKTAV
                     SEAVTNAIIHGYEEDSSKFVFLRCEIEGNTIKIIVEDEGYGIENVEKAMEPLYTSKPE
                     LDRSGMGFTVMKSFMDDVEVSSVKDNGTRIEMTKKINVPK"
     gene            1875..2639
                     /gene="sigF"
                     /locus_tag="JAM15_16550"
     CDS             1875..2639
                     /gene="sigF"
                     /locus_tag="JAM15_16550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigF"
                     /protein_id="HAT6799861.1"
                     /translation="MEVTVAREEKKPLLSHEETLELIEKVQNGDEEAKEILISSNLGL
                     VRSVVSRFLNIGYDREDLFQLGSIGLIKSIYKFDPKFNVKFSTYAVPMILGEIKRYLR
                     DDGMIKVSRSLKQIAVKAKMESEALTKKLGREPSIEELAKAIDVEKEDLVMAMEANFN
                     VEYLQGVIHEEEGSPICLIDKISMKGESEEEKVVDNILLKDILGRLDKRERQIIVLRY
                     FEDMTQSEIGEMLNISQVQVSRIEKKVLSKLKEYIS"
     gene            2919..3356
                     /gene="spoVAC"
                     /locus_tag="JAM15_16555"
     CDS             2919..3356
                     /gene="spoVAC"
                     /locus_tag="JAM15_16555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AC"
                     /protein_id="HAT6799862.1"
                     /translation="MDKNYKKYVDQISPKPTYLKNYTLAFIVGGIICMIGQAINDLYM
                     KVGGLDKLGASSATSITLIFIGAFLTGLGVYDLIGKRAGAGSIIPITGFANSIVSPAM
                     EYKREGYVLGVGANLFKIAGPVLVYGIGSSILCGIIYYIFKMF"
     gene            3510..4523
                     /gene="spoVAD"
                     /locus_tag="JAM15_16560"
     CDS             3510..4523
                     /gene="spoVAD"
                     /locus_tag="JAM15_16560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AD"
                     /protein_id="HAT6799863.1"
                     /translation="MKNKRIGKRTVKLENKPTIISTGTIVGPKEGEGPLKDYFDMIMT
                     DDLYGEKTWELAESKMVETASQQAIQKAGKKLSDVNYMLGGDLINQIVPASFAARELA
                     IPFLGIYGACSTMAEGLCIGSMLIDGGFADLVLSGTSSHYCTAERQFRFPLELGNQKP
                     MTAQWTVTGAGSVLLAPNGDGPKVKYVTVGKVIDEGIDDGNNMGPAMAPAAIDTIYSY
                     FEDTNDDPNSFDIIATGDLGTLGKQIAEDFLKEKGVDISKVYTDCGIEMFNLKEQDVH
                     CGGSGCGCSATVFAGYIYDKLRKKEFNKVMLVSTGALLSPTSTLQKQTIPCVAHAVVI
                     VNE"
     gene            4537..4899
                     /gene="spoVAE"
                     /locus_tag="JAM15_16565"
     CDS             4537..4899
                     /gene="spoVAE"
                     /locus_tag="JAM15_16565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AE"
                     /protein_id="HAT6799864.1"
                     /translation="MLMDYVRVFIVGGIICLIAQVMMDYFKMQTPYVMVTYVTTGVVL
                     TFLGLYEPLVKFAAAGATVPIIGFGYSLATGVIKSIQSDGFLGIFLGGTTATAGGIAA
                     AIFFGYIMSVVFTPKAKP"
     gene            5090..6106
                     /locus_tag="JAM15_16570"
     CDS             5090..6106
                     /locus_tag="JAM15_16570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAT6799865.1"
                     /translation="MVTIKDIARNLGISYSTVSRCLNNNPNVSEKTKKKVVEEANRLG
                     FHFNVNARNLAKKETNRIGVIFSNNFNHQDTRKFFSDIMDSSINSIETNKYDFIIQPN
                     NNISGDSNVYKMVNGQMVDGLVIVSQSIKKEEYDFLKDNNFPHVFIYFKPSFIGEVDN
                     FFWDDNVYGGYIATKHLIDHGHKDIITVTSDDKSSKMHEDRTKGYLNAMEEANLKTEV
                     IKSKMDFESQVEFLEKYIDKIKKASAIFVQQDVPAISIIQELKTTYGINVPEDISIIG
                     YNNIELISYFRSHLSTIDDPREQVIKNGVDSLVNIINKKSTEHIPRKLYPRLIIRNSV
                     KRIK"
     gene            6481..7323
                     /locus_tag="JAM15_16575"
     CDS             6481..7323
                     /locus_tag="JAM15_16575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HAT6799866.1"
                     /translation="MKEKAGIRNAIIAAFIITILAELIGPISFKVMGINVTLLSILWA
                     IFIGMAVSPHLLGRVIPALKKFIGDNEINVSPYLLSLTLYPLGIMFGINAGPKVGILL
                     QAGPALLLQEFGHMGTMLIALPVGVALGLGRSALGGTFSLCRDTALGIIGDKYGLNSP
                     EGIGTLGTYISGSIFGTLLFSFLAPVGVLLGFHPYALAMASGMGSGSMMGAATASLMN
                     TVPQMSEQILAYSATSGLITAVTGIYIELFLSLPVANYYYSKVAPVIERFRGRKTRRT
                     SNKL"
     gene            7338..7802
                     /locus_tag="JAM15_16580"
     CDS             7338..7802
                     /locus_tag="JAM15_16580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799867.1"
                     /translation="MEKTFKTIMEQIKIVLFIYIIICFGQMIALKTQAQDLLIGSVSG
                     FLLVIIAIIIKNFVKKPNLPGFAWATLVAFVLSLPISPVGDIIATNVGKINFMSTVTP
                     LLAFAGISVGNQLDILKTLSWKLVVISFIVMTSTYFGSAFISQTVLRLNGML"
     gene            7816..8961
                     /locus_tag="JAM15_16585"
     CDS             7816..8961
                     /locus_tag="JAM15_16585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HAT6799868.1"
                     /translation="MNELKAKIKEEIKLLSEEKKTSFEKVSDYLFSNPELAFEEYKSQ
                     KALCDLLEENEFNVTKGVGGLETSFEAVYSNGTNGKTVAFLAEYDALPGMGHACGHNI
                     IGTSSVGAGIILKEIMKKHNIEGTVKVFGTPAEERVGGKITMIKEGVFNNVDAALILH
                     PSDASMPDDISFAQVNLKFDFTGKASHAAAFPWEGKSALSGVIALFNSVNSMRLHLKD
                     YARVHGIITDGGSIHNIIPEKSTAIFNVRALSIEYLNEICEMLKNCAKGAAISTRTNV
                     EIVQLDEIYKEIKNDSELVNIVRQNFEVLGEDYVERDLSQGIGSTDTGNLTHEIPAIQ
                     AYIKLKENTATHTDEFAVAAGGEEGKVALIKAIKVLAMCGVDILYSK"
     gene            9005..9940
                     /locus_tag="JAM15_16590"
     CDS             9005..9940
                     /locus_tag="JAM15_16590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1177 domain-containing protein"
                     /protein_id="HAT6799869.1"
                     /translation="MILKQVIEVYDILDKANANGEEVKTYLQGYGEVDVTVKELSSSK
                     GSTDLVKLTIPGKNGKLKGGDAPTLGILGRLGGIGARPEVIGFVSDGDGALVAIAVAA
                     KLLDMQRKGDILDGDVVISTHICPDAPTKEHYPTPFMDSPIDMMTMNENEVDSSCDAI
                     LSIDTTKGNRVINTRGFAISPTVKEGYILKTSDNLLDIMQTVTGKSPFVFPLSIQDIT
                     PYGNNLYHLNSILQPAVATDAPIVGVAITTEMPVAGCATGATNFSDLDSAGRFAIEVA
                     KLFGRNKCDFYDKEEWEMLIKRYGKLNRFQTFGIQ"
     gene            complement(10213..12906)
                     /locus_tag="JAM15_16595"
     CDS             complement(10213..12906)
                     /locus_tag="JAM15_16595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HAT6799870.1"
                     /translation="MNNDNDKNGNKIRRKKVSSSGNTNKPINRTSANKTRSTKNKKKS
                     KKSDKFKKLRVFGIVFLVLLVVGTAGTAGLVFASLRDVTPVTEAVLDKQTNQTTTIKY
                     ANGKTLSTAPSVNKKTPVPLDKISPYLQHAVIAIEDERFYEHKGVDIKGLFRSVLKTL
                     TGTKQGGSTIPMQVSKMLLTTKQQTIPRKIKDIYYAHEMSKTVSKDKILETYLNNFFV
                     GRGLAGAEAGARGYFDKSAADLTLAESALLAGSTKNPSRFSAYKTSKLEGNETKEDLE
                     NKLLFFVNTTDDDLDDPTQVDFDMIEKIKSWELISNDTYRQLKAGTLVVRKAVSNPEA
                     KKRQEIVLKKMLELKYIKQSEYDEAIKAKIEIKLPQSSDKVSSSVEDLIESEVINALM
                     EQGHTNDEAQNLFYNGGLIVNTTIDPKMQDALEEEFDRNSNFPGHMVGPDGVSQPQAA
                     MVILDYKNGEIKALAGGRNISGRKTLNRATNPHQPGSSIKPLAIYTPAIDTLKITQAT
                     ALSDSRGGYKFKENNEWNPRTTTAGHGSMSLRKALAKSSNTIAVKTAEMLGDSYDECV
                     DIMMDYLKNFGITTLKNNHSGSSEASDRKFPSLTLGGMANGITPLQMAAAYGTLANQG
                     VYVEPSIFTTITTFDGQLLVKNAPEEHKVVDPEVAYVVTDMLESVITEGTGGVAALPN
                     GMPVAGKTGTTNSAYDAWFVGYTPYYVGATYIGDDAGRKDDSGNTIKRREVPHGSTST
                     AKLWEKIMEKIHANLTVTEFEVPKNVYFTKINLEDGGKQSSGSKAAFIEGTAPTKVSS
                     QPSSEDTKKPDNNQQQENNNNNNNTGDNGGGSTPPDNNGNNGGGSTTPPDNGGNNGGG
                     STTPPDNGGNNGGGSTTPPDNGGNNGGGSTTPPDGGGTPAT"
     gene            13120..>13757
                     /gene="yunB"
                     /locus_tag="JAM15_16600"
     CDS             13120..>13757
                     /gene="yunB"
                     /locus_tag="JAM15_16600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YunB"
                     /protein_id="HAT6799871.1"
                     /translation="MNRIVDRKTKNEFRKIIAIFLVILFLSVFIGSFIYIDKTLRPTI
                     TVLAETKALELANRSINKAVAEMVEGKINYEDLMDIQLDNNGKITMIQANTIMMNEIA
                     SAIALEIQDELKKDKTASSYIPIGTALGSPILAKYGPKLEVSIEPIGTVSVNFKTEFE
                     SSGINQTRHRIYLEAQTQVKVVIPLITSTKQIKAQIPICETIIVGDVPESYV"
BASE COUNT         5087 a         1707 c         2449 g         4514 t
ORIGIN      
        1 gtatcagatg aacttgatat gacatcaaat aaaacagatt atatatcaaa tgaattgtat
       61 aatttatcta ataagtcaat caaagataat attcctataa agatggctgt gataactaaa
      121 agtaatatgc tgaatcaact gccagattta gtagaattgg agagggtgtt ttcaaaaatt
      181 gaatttaaag tatgttttga tatgtttatg actgatacag ctactttatg tgacatgttt
      241 ataccgtgta caaatacact agagagtgaa gatataattt atagctcaat gaccaatcca
      301 tatataacct ataatgaaag agctgtaaag ccagcacata aattgatgga tgaatattat
      361 ttctttatgg agctagctaa aaaaatggga ttaaatgatt atccttttgt agaaaagaga
      421 acttatttag aaaaagtgat tgaaccactt aagcgttttg acaaaaatct ggatatagaa
      481 aaacttaaaa acaattactt tactatacat aaccttgttg cttgggaaga taagaagttt
      541 gagactccat ctggaaaata cgagctttat tcagaaagta taaaaaactt gggaataaat
      601 ccaacacctg tatatataag caataaatat aaagaaatag aagataaaaa tatttctttt
      661 agattattaa ctaatcatca tgcagatact ttatttagtc agcattttat ggacaaaaaa
      721 tctatagctc aagcatatat aaatcagaga atggctaaaa aagtaggtat tgaggacaaa
      781 gatattgtga tattgaggtc aaaaaaggca aaaataaatg tacaaataaa tatagatgat
      841 ggagtaggta attatatagt aaaaatgtat gttggttggt ggaagaaaca tggaaatcct
      901 aatagtttaa cagacactgg tatatcagat tttggaggtc aggtaacata taatgaaagt
      961 atggtagaaa taatacgaca aaactagtta aatttcattg aaggaataaa aatataatta
     1021 tagaattgat taaaagttac tatttttata aaactattga aggagggatt tttgatggta
     1081 aattattcct tagaacataa gaatctatac atagaattta tgtgctcaga actagaccac
     1141 catgtagcca atgaaataag ggaagaaata gataacttat taagtgtaaa tcaagtaaaa
     1201 aatgttgtat ttaattttga aaatattaat tttatggatt cttcaggtat aggcgtcatc
     1261 ataggtagat ataaaaagat ttctaatgaa gggggacgag tttcagtaat taatataagt
     1321 tcacgagtta agaagatttt tgatttatct gggttaaata aaattattgg catttatgat
     1381 acgtatgaag aagctctaag ttctttgtag ggaggagtat gtgatgaata atattatgga
     1441 agttaaattt tcggcaatat ctgaaaatga aagtttagca agagttatag tagcatcctt
     1501 tgcagctaag ttagacccaa cagtagatga gttagtagat ataaaaactg ctgtctctga
     1561 ggctgttacg aatgctataa tacatggata tgaagaagac agttctaagt ttgttttctt
     1621 aagatgtgag atagaaggaa atactataaa gattatagtt gaagatgaag ggtatggaat
     1681 agaaaatgtg gagaaggcaa tggaaccact ttatacatca aaaccagaac ttgatagatc
     1741 aggaatggga ttcacagtaa tgaaaagctt tatggacgat gtagaggtaa gttctgtaaa
     1801 agataatggg actagaattg aaatgactaa aaaaataaat gtgcctaaat aaagtccaaa
     1861 agtgaggttt tattatggaa gtaactgttg ccagagaaga aaaaaaacct cttcttagtc
     1921 atgaagagac tctagaactt attgaaaaag ttcaaaatgg agatgaagag gcaaaagaaa
     1981 tattaatatc aagcaattta ggtctagtta ggagcgttgt atctagattt ttaaatatag
     2041 gatatgatag agaagattta tttcagttag gttctatagg cttaataaaa tcaatatata
     2101 aatttgaccc aaaatttaat gtaaaattct ctacttatgc agtaccaatg attttaggtg
     2161 aaataaagag atacttaaga gatgatggta tgataaaagt atcaaggtcg ttaaagcaaa
     2221 tagctgtaaa ggcaaagatg gaaagtgaag ctttaactaa aaaattaggt agagagccga
     2281 gtatagaaga attagctaaa gcaatagatg tagaaaaaga agatttagta atggctatgg
     2341 aagctaattt caatgttgag tatttgcaag gcgttattca tgaagaggaa ggttctccaa
     2401 tatgccttat tgataaaata agcatgaaag gagaaagtga agaagaaaaa gtagtggata
     2461 acatattgtt aaaagacata cttggaagat tggataagag agagcgtcaa ataatagttc
     2521 tcagatactt tgaagacatg actcaaagtg aaataggaga gatgctcaat atatcacaag
     2581 ttcaagtatc taggatagag aagaaagtat tgtctaagtt aaaagaatat atatcgtgat
     2641 aatacttatg atatgtagaa taacaaaata taataaatat attactaaaa taaaatgtaa
     2701 taacttttta tgttaagttt ttaaattatt aaaagatatt aaaataataa aaagcattaa
     2761 aaaaataaaa atataaaaac aaggtgtctt tatggaaaaa tagatttttt ctttattaga
     2821 catctttttt attttttgac caaactttag atagtcaaaa taaataatag gtttattttt
     2881 ttaaaattaa caaataatac tttagagagg tgtttagtat ggataaaaat tataaaaaat
     2941 atgtagacca aataagccca aaacctacat atttaaaaaa ttatacactt gcatttattg
     3001 taggtggaat tatttgtatg atagggcaag caataaatga tttgtatatg aaagttggag
     3061 gtcttgataa actaggtgct agttctgcaa catcaataac attaatattt ataggggcat
     3121 ttttaactgg attaggagtt tacgacctaa taggaaaaag agctggagct ggttctataa
     3181 ttccaataac aggttttgct aactcaatag tatctccagc aatggagtat aaaagagaag
     3241 gctatgtatt aggtgtaggt gcaaacctat ttaaaattgc aggaccagtt ttagtttatg
     3301 gtataggttc ttctatttta tgtggaatta tttattatat ttttaagatg ttttagatga
     3361 tttttattta atttaaattt tattaattat gaagaaggta taaaatctga aaatagctac
     3421 taaagtaact aattgagaaa taattgtgca gatttaatta atattaaaaa attgaatagt
     3481 aaaatgcaaa attaaaaagg tgtgaaaata tgaaaaataa aagaattgga aaaagaacag
     3541 tcaagttaga aaataaacca acaataatat cgactggaac tatagtaggt cctaaggaag
     3601 gtgaaggacc actaaaggac tattttgata tgattatgac cgacgattta tatggtgaaa
     3661 agacttggga attagctgaa agtaaaatgg tagagactgc atcccaacaa gctatccaaa
     3721 aggcaggtaa aaaattgtca gatgtaaatt atatgctagg tggcgattta ataaatcaaa
     3781 tagtgccagc atcatttgca gcaagagaac tggctattcc atttttaggt atatatggag
     3841 cttgctctac aatggcagaa ggtctttgta taggttctat gcttatagat ggtggttttg
     3901 ctgatttagt actgtcaggt acatcaagtc actattgtac agcagaaaga caatttagat
     3961 tcccacttga acttggaaat caaaaaccaa tgacagctca gtggacagtt acaggagcag
     4021 gaagtgtatt attagctcct aatggagacg gtccaaaagt aaagtatgtt actgttggta
     4081 aagtaataga tgagggtatt gatgatggta ataatatggg accagctatg gctccagcag
     4141 caatagatac catctattct tactttgaag atactaatga tgacccaaat agctttgata
     4201 taattgctac tggagattta ggtactcttg gaaaacagat agcagaagac tttctaaaag
     4261 aaaaaggtgt agatatatca aaagtttaca ctgactgtgg tatagagatg tttaacctta
     4321 aagaacaaga tgtccactgt ggtggaagtg gatgtgggtg ttcagctaca gtgtttgcag
     4381 gatatatata tgataagttg agaaaaaaag aatttaacaa agtaatgctt gtatcaacag
     4441 gagcactact ttcaccgaca agtacactac aaaagcagac aataccatgt gttgcacatg
     4501 cagtagtaat agtaaatgag taggaagtga tataatatgt taatggacta tgtaagagta
     4561 tttattgtag gtggaattat atgtttaata gcccaagtaa tgatggatta tttcaaaatg
     4621 caaactccat atgttatggt aacatatgta acaactggtg tagttttaac ttttctagga
     4681 ctttatgagc cattagttaa gtttgcagca gcaggtgcaa cagttcctat aataggattt
     4741 ggatattcac ttgctacagg agtaataaaa tcaattcaaa gtgatggttt tttaggtatt
     4801 tttttaggag gtacaactgc tacagctggt ggaatagcag cagctatatt ctttggatat
     4861 attatgtcag tagtatttac tccaaaagca aaaccataaa tctttattaa aagaataata
     4921 agtttttgaa ataataactt tttataaagc aggtggatat cttttagatt ccacctattt
     4981 tttatatttt tatataaaga agcgtttaca taattgaagt tgacaattat ttacaacata
     5041 gtgtagtatt atattatcaa aataaaatga agtgaagtag gggataaaga tggtaactat
     5101 taaagatatt gcaaggaatc taggtatcag ttattcaacc gtttctaggt gcttaaacaa
     5161 taatcctaat gtatctgaaa aaacaaaaaa gaaagtagta gaagaggcaa atagactagg
     5221 gttccatttt aatgtaaatg caagaaattt agcaaaaaaa gaaactaaca ggataggggt
     5281 aatcttttca aataatttta atcatcaaga tactagaaag ttttttagtg atataatgga
     5341 tagttctata aattctattg agactaataa atacgatttc ataatacagc ctaataataa
     5401 cattagtggt gatagtaatg tatataaaat ggtaaatgga caaatggttg acggattagt
     5461 aattgtgtct caatcaataa aaaaagaaga gtatgatttt ttaaaagaca ataattttcc
     5521 acatgtattt atatatttta aaccatcttt tataggagaa gtagacaatt tcttttggga
     5581 cgataacgtg tatggaggtt atatagctac caagcattta attgaccatg gtcataaaga
     5641 tataataaca gtaacttcag atgataagag ttcaaaaatg catgaagata gaaccaaggg
     5701 atatttgaat gctatggaag aggcaaattt aaagaccgaa gtcattaaat ctaaaatgga
     5761 ttttgaatct caagttgaat ttttagaaaa atacattgat aaaataaaaa aagcttcagc
     5821 tatatttgta caacaggatg taccagcgat ttctataata caagagttaa aaactactta
     5881 tggtataaat gtaccagaag atatttccat aatagggtat aataatattg aattaatatc
     5941 atattttagg tcgcatttat caacaataga tgacccaaga gagcaagtta taaaaaatgg
     6001 agtagatagt ttagtaaata taataaataa aaagagtaca gaacacattc caagaaaatt
     6061 atatccaagg ttaataatac gaaatagcgt taaaagaata aagtagtaag cttttaagta
     6121 tcaaaagttt attaaaaata ttatagatta tgtgaagttt tttaacaaat aatataaata
     6181 aaaattaaaa ggagtaggtg tatataagta cattgtactc ctttatttat tgagatagtt
     6241 tttataatat gaatgaataa ttttattcaa ttatttgaaa atccgttatt ttaacaatat
     6301 aaattaataa attatttgta ttttatatca tgaatctata atattttttt gattcataac
     6361 taaaagtata taaaaatgat gaataaatat atattataca ttatcaatga taggttatat
     6421 aataaaatca ctaacaatta tattataaga aaattataaa aattacaagg aggtatagaa
     6481 atgaaagaaa aagcagggat tagaaatgcc ataatagcag cctttataat cacaatattg
     6541 gcagaattaa ttggacctat ttcatttaaa gttatgggaa ttaatgtaac tttacttagt
     6601 atactatggg ctatattcat aggaatggct gtttctcctc atttattagg gagagttata
     6661 ccagccttaa aaaaatttat aggggataat gaaataaatg tatctccata tttattatct
     6721 ttgacactat atccattagg gataatgttt ggaattaatg cagggcctaa agttggtata
     6781 ttacttcaag caggaccagc acttttatta caagaatttg gtcatatggg tacaatgttg
     6841 atagcattac ctgttggagt agcattgggt cttggaagaa gtgcattagg tggtactttt
     6901 tcattatgtc gtgacacagc actaggaatt attggagata agtatggatt aaactcacca
     6961 gaaggtatag gaacactagg aacttacata agtggtagta tatttggaac attattattt
     7021 tcatttttag caccagtggg tgtactttta ggatttcatc catatgcttt agcaatggca
     7081 tcaggaatgg gtagtggttc aatgatggga gctgcaacag catcattaat gaatacggtt
     7141 ccacaaatgt cagagcagat tttagcatat tcagctacta gtggattgat tacagctgtt
     7201 actggaatat atatagaatt attcttatct ttaccagtag ccaactacta ttatagcaaa
     7261 gtagctccag ttattgaaag atttagagga agaaaaacaa gaagaacaag taataaattg
     7321 taaaggagga tatatatatg gaaaaaactt ttaagactat tatggagcag ataaaaatag
     7381 tattgtttat atatattatt atttgctttg gacaaatgat agcacttaag actcaggctc
     7441 aagatttgtt gattggaagt gtatctgggt ttttgttagt gataattgct attataataa
     7501 agaattttgt taaaaaacct aatttaccag gttttgcatg ggctacatta gttgcattcg
     7561 ttttatcgct tccaatatct ccagtggggg atatcatagc aacaaatgta gggaaaatca
     7621 attttatgtc tacagtaaca ccattattag cttttgcagg aatctctgta ggtaaccaat
     7681 tagatatact aaagactttg agttggaagt tagtagttat atcatttata gttatgacat
     7741 ctacttactt tggttctgct tttatatctc aaacagtttt aagattaaat ggaatgcttt
     7801 aaggaggtag taaatatgaa tgaattaaaa gcaaaaatta aagaggaaat aaagttatta
     7861 tctgaagaga aaaagacatc atttgaaaaa gtttctgact atttattttc aaatccagaa
     7921 ttagcatttg aggagtataa gtcacaaaaa gcattatgtg atttgttaga agaaaatgaa
     7981 tttaatgtaa ctaaaggtgt aggaggatta gaaacatctt ttgaagctgt gtattcaaat
     8041 ggaactaatg ggaaaacagt tgctttttta gctgaatatg atgcacttcc aggaatggga
     8101 catgcatgtg ggcacaatat catagggaca agttctgttg gtgcaggtat catattaaaa
     8161 gaaatcatga aaaaacataa tatagaaggg actgtaaagg tttttggaac acctgcagaa
     8221 gaaagagtag gtggaaaaat aactatgatt aaagaaggtg tatttaataa tgtagatgct
     8281 gcattaattt tacatccaag tgatgcttca atgcctgatg atatatcatt tgctcaagtt
     8341 aatttaaaat ttgattttac tggtaaggca tcacatgctg ctgcttttcc ttgggaaggg
     8401 aaaagtgcct taagtggagt aatagcacta tttaacagtg taaatagcat gagattacat
     8461 cttaaagatt atgcaagagt acatggaatt ataactgatg gaggtagcat acataatata
     8521 attcctgaaa aatctacagc tatatttaat gtaagagcct taagcataga atatttaaat
     8581 gagatttgtg aaatgcttaa aaattgtgct aaaggagctg caatttctac tagaactaat
     8641 gtagaaatag ttcaattaga tgaaatatac aaagagatta agaatgattc tgaattagtg
     8701 aatatagtta gacaaaattt tgaagttttg ggtgaagact atgttgaaag agatttaagt
     8761 caaggtatag gttcaactga tacaggaaat ttaactcatg agatacctgc aatacaagca
     8821 tatataaaat taaaagaaaa tactgcaact catacagatg aatttgctgt tgcagctggt
     8881 ggtgaagaag gcaaagtagc acttataaaa gcaattaagg tgctagcaat gtgtggagta
     8941 gatattttgt atagtaaata atatataatt taaaaatata ttaagaaagg aaatcggatt
     9001 agacatgata ttaaaacaag taatagaggt ttatgacatt ttagataaag caaatgctaa
     9061 tggggaagaa gtaaaaactt acttacaagg ttatggtgaa gtagatgtaa ctgtaaaaga
     9121 attgtcttca agtaaaggtt caacagattt agtaaagctt acaattcctg gtaaaaatgg
     9181 aaaattaaaa ggtggagatg ctcccactct tggtatttta ggtagactag gagggattgg
     9241 agcaagacca gaagttatag gttttgtctc agatggtgat ggagcattgg tagcaattgc
     9301 agtggctgct aaacttttgg atatgcaacg aaaaggggat atattagatg gtgatgttgt
     9361 aatttcaact catatttgcc cagatgctcc aactaaagaa cactatccta ctccttttat
     9421 ggattctcca attgatatga tgactatgaa tgaaaatgaa gttgatagta gttgtgatgc
     9481 aatactttct atagatacta ctaaaggaaa tagagtaatc aatactagag gatttgcaat
     9541 atcgccaact gttaaagaag gctacatatt aaaaactagt gataaccttt tagatattat
     9601 gcagactgta acagggaaat ctccatttgt attccctttg tctattcaag atataacacc
     9661 atatggaaac aatctgtatc acttaaatag tattttacaa ccagcagtag ctacagatgc
     9721 accaatagta ggagtagcaa ttacaacaga gatgcctgtt gctggatgtg ctacaggtgc
     9781 aactaatttt agtgatttag attcagctgg gagatttgca attgaagttg ctaagctatt
     9841 tggtagaaat aagtgtgatt tctatgataa agaagagtgg gaaatgctta ttaagagata
     9901 tggcaaatta aatagatttc aaacatttgg tatacagtaa ttagaaaaat attaagttta
     9961 tataatttgt gatataacta tttaagaata tataaacaat taggaataaa attaagaata
    10021 aagcacttag ttaaaaactt taaaaataaa atatttattt gcttatataa aaaggaggat
    10081 tctggttatg tggattctct tttttatgaa cataaataat atgttgtaat tgtaaaaaag
    10141 gagtgtttca aagtgatttt tttaatcacc ttgatacaac tccttatatt tttatttaaa
    10201 ttctattttt tattaagttg ctggagttcc accaccatca ggaggagtgg tagagccacc
    10261 accattattt ccaccattat caggaggagt agtagagcca ccaccattgt ttccaccatt
    10321 atcaggagga gtagtagagc caccaccatt gtttccgcca ttatcaggag gagtagtaga
    10381 gccaccacca ttgtttccat tattatcagg aggtgtagaa ccaccaccat tatcacctgt
    10441 attattattg ttattattat tttcttgttg ttggttattg tctggttttt ttgtatcttc
    10501 agatgatggt tgagaactta ctttagtagg agcagtacct tcaataaatg ctgctttaga
    10561 gccagaagat tgctttcctc catcctctaa attaattttt gtaaaatata catttttagg
    10621 aacttcaaat tcagtaaccg ttaaattagc atgtattttt tccataattt tttcccatag
    10681 ttttgcagta ctagtacttc catgtggtac ttctctacgt tttatagtgt taccagaatc
    10741 atcttttcta ccagcatcat ctccaatata agttgcacca acataataag gagtgtaacc
    10801 gacaaaccaa gcatcatatg cactatttgt agtacctgtt ttacctgcta caggcattcc
    10861 atttggaagt gcagcaacac caccagtacc ttcagtaatt acactttcta acatatctgt
    10921 aacaacataa gctacttcag ggtctacaac tttatgttct tcaggagcat ttttaactaa
    10981 taattgacca tcaaaggtag ttatagtagt aaaaatagaa ggttctacat aaacaccttg
    11041 atttgccaat gtaccataag cagcagccat ttgaagtgga gtaataccat tcgccatacc
    11101 acctagtgtc aatgatggga attttctatc acttgcttca gatgaacctg agtgattatt
    11161 ctttaaagtt gttataccaa agttctttaa gtaatccatc attatatcta cacattcatc
    11221 ataagagtct ccaagcattt cagcagtttt gacagctatc gtgtttgaag atttagcaag
    11281 tgctttacgt aaactcatag aaccatgacc agcagtagta gttcttggat tccattcatt
    11341 attttcttta aacttatatc ctcctcgaga atcacttaga gcagttgctt gtgttatttt
    11401 tagagtatca atagctggcg tatatattgc taaaggtttt atagaagaac ctggctgatg
    11461 agggttagta gcacgattta aagtttttct accacttata tttcttcctc cagctagtgc
    11521 ttttatttca ccatttttat aatctaagat taccattgca gcttgcggtt ggctaactcc
    11581 atcagggccg accatatgtc ctgggaaatt gctatttcta tcaaattctt cttctaaagc
    11641 atcttgcatt ttagggtcta tagttgtgtt tacaattaga ccaccattgt agaataagtt
    11701 ttgagcttca tcatttgtat gtccttgttc cattaaagca tttataactt cactttcgat
    11761 aaggtcttct acagatgaag aaactttatc tgatgattga ggcaatttta tttctatttt
    11821 agctttgatt gcttcatcat attcactttg ttttatatat ttcaattcta acattttctt
    11881 taaaacaatt tcttgtcttt ttttagcttc agggttactt acagcctttc taacaactaa
    11941 tgtacctgct tttaattgtc tataagtatc attagatata agctcccaag attttatttt
    12001 ttcaatcata tcaaagtcca cttgagtagg gtcatctaaa tcatcatcag ttgtgttaac
    12061 aaaaaataat aatttatttt ctaaatcctc cttagtttca tttccctcta acttagaagt
    12121 tttataggct gaaaatcttg atggattttt agttgaacca gcaagaagtg ctgactctgc
    12181 tagagtgagg tcagctgcag acttatcaaa ataaccacgt gcaccagcct cagcacctgc
    12241 tagacctcta ccaacgaaga agttatttaa ataagtttct agtattttat ctttacttac
    12301 tgttttactc atctcatgtg catagtaaat atcctttatt ttacgaggta tagtttgctg
    12361 tttagttgtt aacagcattt tggatacctg cataggaata gtactaccac cttgcttagt
    12421 acctgtaagg gtctttaata ctgacctaaa taaaccttta atatcgacac ccttatgctc
    12481 ataaaaacgc tcatcttcta ttgcaattac agcatgttga agataagggg aaatcttatc
    12541 taatggaacg ggtgtctttt tatttacact tggagctgta gacaatgttt ttccattagc
    12601 gtatttaata gtagttgttt ggttcgtctg tttatctaaa acagcttctg taactggagt
    12661 tacatctctt agtgacgcaa atactagacc agcagtacct gctgtaccaa caactagtaa
    12721 aactaaaaat actatcccaa atactcttag ttttttaaat ttatcgcttt ttttagattt
    12781 tttcttgttt tttgttgaac gagtcttgtt agctgaagtt ctattaattg gtttatttgt
    12841 attaccagat gagctaactt tttttctcct gattttattt ccatttttat cattatcgtt
    12901 attcataaga ttttaacctc cttacttaat gcaatattat aacacaaata ggagtagttt
    12961 tgtaattaat agaaaaaatg aatttgctat aatattctgt acattgtata tgtataaacg
    13021 taatatatta aaaagtctat atttttattt tatttatttt tgacaaatat tataaaaatt
    13081 atgccaaagc tacatataaa taaataggag gggataattt tgaatagaat agtagataga
    13141 aaaacaaaaa atgaatttag aaaaatcata gctatttttt tagtaattct tttcttgtct
    13201 gtatttatag gcagttttat atatatagat aaaactttaa gaccgacaat aacagtttta
    13261 gcagagacta aagctcttga actagcaaat aggtcgataa ataaagctgt tgctgagatg
    13321 gtagaaggaa aaataaatta tgaagattta atggatatac aacttgataa taatggtaaa
    13381 ataactatga tacaagcaaa cactataatg atgaatgaaa ttgcatctgc aatagcttta
    13441 gaaatacaag atgaattaaa aaaggataag acagcaagtt cttacatacc tataggaaca
    13501 gcattaggaa gtcctatatt agctaaatac ggtcctaaac ttgaagtgtc tattgaacct
    13561 ataggaacag tatcagtaaa ctttaaaacg gaatttgagt cttcaggtat aaatcaaact
    13621 agacatagaa tatatttaga agctcaaaca caagttaaag tagtaatacc acttataact
    13681 tcaacaaaac aaattaaagc tcaaatacct atttgtgaaa ctataatagt aggtgatgtt
    13741 ccagaaagtt atgtaaa
//
LOCUS       DACTZW010000105        13052 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.106, whole genome shotgun sequence.
ACCESSION   DACTZW010000105 DACTZW010000000
VERSION     DACTZW010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13052
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.106"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            106..669
                     /locus_tag="JAM15_16605"
     CDS             106..669
                     /locus_tag="JAM15_16605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799872.1"
                     /translation="MNKVYIVTTYTGTILSYLIRNISKKLYTHVSISLNENLKPMYSF
                     GRLNPRNPFIGGFVEENINQGLYAIRKNTVCRVYSLEVDNLQYENLYKNIKLISDYRE
                     DYYYDTMALIYLLMNIQRQSEYKYVCSNFVADMLEKSEIDILNKQAFEVTPNDFYNLS
                     GLTLEYEGLLSEYNSRQHSYVSKIANI"
     gene            1066..2766
                     /locus_tag="JAM15_16610"
     CDS             1066..2766
                     /locus_tag="JAM15_16610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799873.1"
                     /translation="MKRYLKTYGVALIIVIIYAFIKLPVLRLDFTSLFSVGIIFFVVA
                     GILDMMLDRNERASKMAKYNFSIAIALLVYIVVVPFITSTPVLHAKSYRELLGKVTES
                     KFTDDISPVSVNDIRLVDEDMAMKLGDKKLGEVPAIGSVSKLGKFHIQNVDGELYWVA
                     PLVHRDIIKWITSLSGTSGYVKVSASNPQDVQLVQEIDGKPIKIVYQPEAYLHQDLQR
                     HLYIHGIVNVGMTDFTLEINDEGRPYWVVSLYEHKIGYGGANATGIATVDAETGKINV
                     YDVKNTPKWVDRIQPQSFVTDQIKDWGVYVNGFLNSVISEKGVLVPTEGTSLVYGNDN
                     RSYWYTGITSSGGDESTIGFMLVDSRTKEARLYKQPGATETAAMKSAEGNVQEKNYEA
                     TFPVMYNILGQPTYVSSLKDKAGLVKRVAFVSVEDYNVLGIGEDKNEALRNYKDALES
                     KGNDLKLDNDLKDEVLEGTVTRISPDVRGGNTNYYVTLDSNKDIIFRATSKVSSELPL
                     TQVGDKVKISYSKEESGVIEMSEFDNLNIANFEDKKAKEKTGTDENTDSKDSENQGNV
                     "
     gene            2936..3553
                     /locus_tag="JAM15_16615"
     CDS             2936..3553
                     /locus_tag="JAM15_16615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799874.1"
                     /translation="MTNMEKEILLLISRVRCVTESQFRKIYGDQKRYNKKNFKKTLRK
                     MCSEYTLKKYPCDVDYYNYKDLSYVYYLNGSKLFKGDDLIKALVGSELVVRINTAGCD
                     VKRFYRNVSVDDVKYDLFIEYTDQFDNIKQVLVDVDLNNEIDISKYENLSKKIDKSTI
                     PFFKVPNVLVVTPDNLSELNDLERYDNEYSINFIDLGLNKLFNCI"
     gene            3914..5107
                     /locus_tag="JAM15_16620"
     CDS             3914..5107
                     /locus_tag="JAM15_16620"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HAT6799875.1"
                     /translation="MSIIVQKYGGSSVADTEKIKSIAENIIERRKENPQMVIVVSAMG
                     KSTDEYITLAKELSNEPSKRELDALMSTGEMISASLLSIALNALGCKAISYNAYQLNI
                     KTSGLHGKSQIDDINVNRIKNSLDEGNVVIVTGFQGINEDGDVTTLGRGGSDTSAVAL
                     AVKLNGKCEIYTDVDGIYFTDPRKYSKASKLDEIEYEEMLELASLGAQVMHSRSIELA
                     QKYGVEIYVGRTCGTEKGTYIRGGKDMKLEDKVITGLATSDDDSSITIKDFKAENISS
                     LFEDIATIGISVDMISQTAPILDKISVSFTVPKEELGECKKIVSKYTDEEHVVIDNNI
                     TKFSLVGLGMKNTSGVAAKVFKIFNENGIMIKLITTSEIRITCAINSDDKQVAIEKIA
                     EVFNI"
     gene            5125..6417
                     /gene="lysA"
                     /locus_tag="JAM15_16625"
     CDS             5125..6417
                     /gene="lysA"
                     /locus_tag="JAM15_16625"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006784782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HAT6799876.1"
                     /translation="MKLHGTMTVNNDELYIGGVSCLELSKKYQTPLYVFDEALVRQNC
                     REYIEYFKAREGKNKVAYAGKAFLPLYMCNLINEEQMCLDVVSGGELYTAYKSNFPME
                     KVFFHGNNKTKEEINMGLDLGVGKFVVDNFYELDLLEALCEDKGKTQEIYFRITPGIE
                     AHTHDYIKTGQIDSKFGFALVNGDLFRAIEKLSEYKNIKLVGLHAHIGSQIFDVEPYI
                     DTVDIMMNLVKEIKEKFNIQLTEIDLGGGVGVYYSEGDKPKTIKEFCETIITKAETSC
                     KELGIEVPTLVIEPGRSIVANAGSTLYTVGSIKDIKDVRVYVSVDGGMTDNVRPSLYQ
                     ASYECSIVNKINHEAMNHVTIAGKCCESGDILIGDINIMDIKSGDILITTSTGAYGYS
                     MSSNYNKIPRAAVVSVFDGNDKIICKRQSYEDLLALEI"
     gene            6634..7293
                     /locus_tag="JAM15_16630"
     CDS             6634..7293
                     /locus_tag="JAM15_16630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HAT6799877.1"
                     /translation="MRGRVILLISILSIFLVGCSFNKKDEINLVEQGKTYLEKHNYKK
                     AMESLSSALEEDSTNENARAMYMQAMRMSNMTEFEELKNYEGAIKELKLIEKIKNGSS
                     VIKEEATKKKEELTKLEKEQNEAEEQRKKKAKDTAGEDRYRVESDARKSSYSGSSKNN
                     KSSSKNNDKKSDSNKSDNNNSSSQNQEKPNNSNPTPAPTPQDTTGGSDSGGNSQNSNN
                     Q"
     gene            complement(7448..8533)
                     /locus_tag="JAM15_16635"
     CDS             complement(7448..8533)
                     /locus_tag="JAM15_16635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAT6799878.1"
                     /translation="MIIISKENIKYYLIVVFIGILFFKFINTPSNFISSIEGFLKFFS
                     PFLLAILLALLLNPLVMLFEVKFKAHRLLAIFLSYIFIGFILAFAIRLLIPSIANTLN
                     RLINEMPMYTDYIDSFIEKNMSNIDFLKTLIPHIQHSLDNLLKEASNFVGKIPKNFLI
                     YTLSISSMLFNMTMGFILSIYIIYDKEKIALGFKRFLYSSTARNKADNIIEFFRTTHD
                     IFYDYLLGRILDSLIIGIIAFLGFQFVIRIENALFLASIIFLGNIIPYFGPFIGAIPP
                     IAMTILYSPQKTIWVIAFLFILQQLDGNFIEPKVMGNQVGIGAIWVISAILVGQSLFG
                     FIGVFLSVPIAAVVKTYVDKYIDNRLQ"
     gene            8724..9440
                     /locus_tag="JAM15_16640"
     CDS             8724..9440
                     /locus_tag="JAM15_16640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HAT6799879.1"
                     /translation="MRINKYIASCGIASRRKSEEIILGGRIKVNGSVVKELSFNIDEE
                     KDIVEFDNKKVKPSENYIYIVLNKPEGYITTVKDQFNRPSVIDILKDVRERVYPIGRL
                     DYETSGLLILTNDGDLTYKLTHPKHEIDKTYVASVKGIISDDEIRQFETGLKIEDYTT
                     APAKIRVTKENKEKNYSVCEITIHEGRNRQVRKMCKAINHPVLNLRRISVGKIVLKDT
                     KVGEYRYLTEDEIKYLKSIK"
     gene            9498..10076
                     /locus_tag="JAM15_16645"
     CDS             9498..10076
                     /locus_tag="JAM15_16645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAT6799880.1"
                     /translation="MAYAKYLTKITDINKFYLENIINEGDIVIDATMGNGYDTRYLAE
                     KVGEKGFVYAFDIQEEAIKSTRKKLEKEGYTDRVKLIFDGHEKMNQYIKEEVSCVLFN
                     LGYLPRAKHSIITKPDTTLKAIKLSLEMLKENGVISIAIYTGHDGGQEEKDCIYNLVN
                     NLNQDEFNVLESKFLNQVNNPPQLILIEKKKA"
     gene            10476..11348
                     /locus_tag="JAM15_16650"
     CDS             10476..11348
                     /locus_tag="JAM15_16650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAT6799881.1"
                     /translation="MEETNEMKDSKHLISNIQSQYTRLSKGQKLIAQYILNNYDKVAF
                     MTACKLGETVGVSESTVVRFANALGYSGYPKLQAALQELIKNKLTTVQRVEMAHDYSD
                     DFAILNKVLKSDIDNIRSTLEEIDERAFKEASNKLLRARKIYILGMRSSFVVAQYLGF
                     YLDIILDNVHIIRMDMGDAFEQIVRINEEDVIVAISFPRYSKKSYQIVNYAKEKGAHV
                     ISLTDSLFAPVASLADNTLLVKSNMASFVDSLVPALSISNALAISVGMKEKEDIKQHF
                     DDLEQIWKRYSVYE"
     repeat_region   12179..12518
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=12179..12197
                     /rpt_unit_seq="gttttatattaactatatg"
     gene            12639..12923
                     /locus_tag="JAM15_16655"
     CDS             12639..12923
                     /locus_tag="JAM15_16655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799882.1"
                     /translation="MLVYNKSFYPNDIFPRLDFSKIKKQLKLIDNDLSDFGSICIIEK
                     EHYTISVNSIGEINVYYDLEYENKVYRIVYEIEKLFKSQVGRFSISTYRN"
BASE COUNT         5365 a         1295 c         2227 g         4165 t
ORIGIN      
        1 ccttaaaatc aaaatttgta aaaccacatt tattatgtta gaatatctta tgatattaaa
       61 ttgtaagtgt ataatattat ttagttacta gattgggggg aaatgatgaa taaagtctat
      121 attgtaacaa catatacagg aactatatta tcttacttaa taaggaatat aagtaaaaag
      181 ctgtatacac atgtgtcaat atcattaaat gaaaatctaa aaccaatgta ttcttttgga
      241 aggctaaatc caaggaatcc atttattgga ggatttgttg aagaaaatat aaatcaagga
      301 ttatatgcta taagaaaaaa cactgtgtgt agggtatatt cgttagaagt agataattta
      361 caatatgaaa atctatataa aaatataaaa ttaattagtg attatagaga agattactat
      421 tacgatacaa tggcattaat atatttacta atgaatattc agagacaatc tgaatataaa
      481 tatgtatgtt caaattttgt tgctgacatg ttagaaaaaa gtgagataga cattttaaat
      541 aaacaagcat ttgaagtaac gccaaatgat ttttataatt tatctggctt aaccttagag
      601 tatgaaggtt tattatcaga atataattct agacaacatt cttatgtatc aaaaatcgca
      661 aacatttaaa aacttgattt agagtttttc atataaaaaa atattgctag ataattaggc
      721 tgaagatagt agtttaactt cgataggatt aagaatttgt aaatcttagt tagaatactt
      781 tcttcagttt ttaaatttct gctaatattt gtatttttat aatatttttg gatatatata
      841 atacagaata gtgcaaaaat cccactcctt taggtgcggg atggatagca caaacagtgt
      901 ataaaaagta tttatacata cacgtataat gttaaatata gttgaataag cagaactata
      961 aatatataaa gatatcttaa tatataataa atatgataaa tatttatttt ttgtaaatat
     1021 atggatataa tagtaataat aacatttttt agagaggagt attaaatgaa acgatatctt
     1081 aaaacatatg gagttgcatt aataattgta ataatttatg catttattaa attacctgta
     1141 ctaagattag attttacatc tttattttca gtaggaataa ttttctttgt tgtagcagga
     1201 atactagata tgatgttaga tagaaatgaa agagcatcta aaatggctaa atataatttt
     1261 tcaatagcaa tagctttgct tgtgtatatt gtagtagttc cctttataac ttctacacct
     1321 gtacttcatg caaaatcata tagagaacta ttgggaaaag taactgaaag taaatttact
     1381 gatgacatta gccctgtcag tgtaaatgac attcgtcttg tagatgaaga tatggcaatg
     1441 aaattaggtg acaaaaagct tggagaagtt cctgcaatag ggagtgtatc caaattagga
     1501 aaatttcata tacaaaatgt agatggagag ttgtactggg tagcgcctct tgttcacaga
     1561 gacataatta aatggataac atctctaagt ggtacaagtg gttatgtaaa agtatcagct
     1621 agtaatcctc aagacgtcca attagttcaa gaaatagatg gaaagccaat aaagatagtt
     1681 taccaaccag aagcctactt acatcaggat ttacaaagac atttatacat acatggtatt
     1741 gtaaatgttg gtatgacaga tttcactctt gaaataaatg atgaaggaag accttattgg
     1801 gttgtaagtt tatatgaaca taaaattggc tatggaggag caaatgcaac aggaatagcc
     1861 actgttgatg cagaaactgg aaaaataaat gtttatgatg ttaaaaacac acctaaatgg
     1921 gtggatagaa tacaaccaca aagctttgta acagaccaga ttaaagactg gggtgtttat
     1981 gttaatggat ttttaaactc tgttatatca gaaaagggag ttttagtacc aacagaaggt
     2041 acatcattag tttatggcaa tgataacagg tcttattggt atacaggtat aacatcttca
     2101 ggtggagatg aatctacaat tggatttatg ttagttgatt ctagaacaaa agaagctaga
     2161 ttatataaac aaccaggagc tactgaaacg gctgcaatga aatcagctga aggtaatgtt
     2221 caagaaaaaa attatgaagc gacgttccct gtaatgtata atatattggg tcagccaaca
     2281 tatgtatcat cattaaaaga taaggctggt cttgttaaga gagttgcatt tgtatctgtt
     2341 gaagattata atgtacttgg aataggtgaa gataagaatg aagcattaag aaactataag
     2401 gatgcattag aatctaaggg taatgattta aaacttgata atgatttaaa agatgaggta
     2461 ttagaaggca cagtgacaag aataagccca gatgtgcgag gtggtaacac taattattat
     2521 gtaactttag attcaaataa agatataata tttagggcta cttcaaaagt atctagcgaa
     2581 ttgccattga ctcaggttgg tgataaagtc aaaatatcgt attcaaaaga agaatctggt
     2641 gtaatagaaa tgtcagaatt tgataaccta aatattgcaa actttgaaga taaaaaagca
     2701 aaagaaaaaa caggaactga tgaaaataca gattccaaag attctgaaaa tcaaggtaat
     2761 gtataattta aataaaaaga ttgataatag tatttaacat agtgatagct aatttttata
     2821 gaatttaatt ctataaaaat tagctatttt attttaattc tttgtaaatt taatgtcata
     2881 aaattaatat aatattagta caactttgca aataatactt caaggagaat gtactatgac
     2941 gaatatggaa aaagagattt tacttttaat tagcagggtt agatgtgtta cagagtctca
     3001 atttagaaaa atttatggag accaaaaaag atacaataaa aaaaatttta aaaaaacttt
     3061 gagaaaaatg tgtagtgaat atacactaaa aaaatatcct tgtgatgtgg attattataa
     3121 ttataaagac ctctcttatg tatactattt aaacggtagt aaacttttta agggagatga
     3181 tttaataaag gctctagtag gatcagaatt agttgttaga atcaatactg caggttgtga
     3241 tgtaaaaaga ttttaccgaa atgttagtgt agatgatgtg aaatacgatt tatttattga
     3301 atatacagac caatttgata atataaagca agttttagtt gatgttgact taaataatga
     3361 aatagacatt tctaaatacg aaaatctttc taaaaaaata gataaatcta caattccatt
     3421 ttttaaagta ccaaacgttt tggtagttac accagataat ctatccgaat taaatgattt
     3481 agagagatat gataatgagt atagcataaa ttttatagat ttaggattaa ataaactatt
     3541 taattgtata taagctaact ttagaaaaga aaactatcga tttgccacat tttgtaaaat
     3601 aattgttgca atattatata gaatatgata aaactatatt aataaattaa ttaaaaataa
     3661 tgagcctagg gtagaggtag ctgtattcaa tagtattcaa taggagctgg taagcgttga
     3721 taattgatga aagggtatat agccgaagaa attttgttga cggacaaatt ttctggactt
     3781 atgcagaaca tgcataaggc tgtcactttt aaagtggtga gctacaaggt tacttggtct
     3841 atgaaattta cacgtccaaa gtataccttt gggcgttttt atttatcaaa atttagcttg
     3901 agggggagaa agcatgagta taattgttca aaaatatggt ggaagttcag tagcagatac
     3961 tgaaaaaata aaatcaatag cagaaaatat aatagaacga agaaaagaaa atccacaaat
     4021 ggtaatagtt gtgtctgcta tgggaaaatc cactgatgaa tatataactt tagcaaagga
     4081 attgagtaat gaacctagta agagggaatt agatgcttta atgtctactg gtgaaatgat
     4141 ttcagcatct ttattatcaa tagcattaaa tgcacttgga tgtaaagcta taagttataa
     4201 tgcttaccag ttaaatataa aaacgagtgg tcttcatgga aagtctcaaa ttgatgatat
     4261 aaacgtaaac agaattaaaa atagtttaga tgaaggaaat gtcgttatag taactggatt
     4321 tcagggaatc aacgaagatg gtgatgtaac cactcttgga agaggtggtt cagatacatc
     4381 tgctgtagct cttgcggtta aattaaatgg aaaatgtgag atatatacag atgttgatgg
     4441 aatttatttt acagacccaa gaaaatattc aaaggctagt aaacttgatg agattgaata
     4501 tgaagaaatg cttgagttag cgagtttagg agcacaagta atgcattcaa gaagtataga
     4561 gcttgcacaa aaatatggtg ttgaaatcta tgtcggacgt acatgtggta cagaaaaagg
     4621 aacatatata agagggggaa aagacatgaa attagaggat aaagtaataa caggattagc
     4681 tactagtgat gatgacagtt ctataacaat aaaagatttt aaagctgaaa atatatctag
     4741 cttatttgaa gatatagcaa ctataggtat aagtgtagat atgataagcc aaactgcacc
     4801 tattttagat aagataagtg tatcatttac agttccaaaa gaagagctgg gagaatgtaa
     4861 aaagatagta tctaaatata cagatgaaga acatgtagtg attgataata atatcactaa
     4921 attttcttta gtaggtcttg gtatgaaaaa tacttctgga gttgctgcta aagtatttaa
     4981 gatattcaat gaaaatggta taatgataaa acttataact acatcagaga ttcgtataac
     5041 ttgtgctata aattctgatg ataagcaagt agctatagaa aaaatagcag aagtatttaa
     5101 tatataaaat ttggggaggc tattatgaaa cttcatggaa ctatgactgt aaataatgat
     5161 gaattatata ttggaggagt gagttgttta gaacttagta aaaaatatca aactccactt
     5221 tatgtatttg atgaagcttt agttagacaa aattgtagag aatatataga atattttaag
     5281 gctagagagg gaaaaaataa ggttgcttat gcagggaaag cttttttacc tctttacatg
     5341 tgtaatctta taaatgaaga acaaatgtgt ttagatgtag tttcaggagg cgagttatat
     5401 acagcttata aatcaaattt tcctatggaa aaagttttct ttcatggaaa caataagact
     5461 aaagaagaaa taaacatggg attagattta ggtgtaggta aatttgtagt ggataatttt
     5521 tatgaattag atttgcttga agcattatgt gaagataaag gtaaaactca agagatatac
     5581 tttagaataa ctcctggtat agaagctcat acacatgatt atataaaaac tggacagata
     5641 gattctaaat ttggatttgc tttagtaaat ggagatttat ttagagcaat agaaaaatta
     5701 agtgaatata aaaatattaa acttgtaggt cttcacgctc atatagggtc acaaatattt
     5761 gatgtagaac catacataga tacagtggat ataatgatga acttggtaaa agaaataaaa
     5821 gaaaaattca acatacaact aacagaaatt gacctaggtg gaggagttgg cgtttattat
     5881 agcgaaggag ataaacctaa aactataaaa gagttttgtg aaaccataat cactaaagca
     5941 gaaacttcat gtaaagagct tggaatagaa gtacctacat tggtaataga accaggaaga
     6001 tcaatagttg caaatgcagg aagtacattg tatacagtag gttctataaa agatataaaa
     6061 gatgttaggg tttatgtaag tgtagatgga ggtatgacag ataatgtaag accttcgttg
     6121 taccaagcta gttatgagtg tagtattgtg aataaaatta atcatgaggc tatgaatcat
     6181 gtaacaatag ctggaaaatg ttgtgagagt ggagatatat taattggaga tataaacata
     6241 atggatatta aaagtggaga tatacttata acaacatcaa ctggtgcata tggatattca
     6301 atgtcttcaa attataataa aataccaaga gcagcagtag tatcagtatt tgatggaaat
     6361 gataagataa tttgtaagag acaaagctat gaggacttat tagctttaga gatataaaat
     6421 ggagaagtat ataataaaaa ttaaatatta aagtttatta tgagcagatt tgctaggata
     6481 tgtatctcta aattaatttt tggtttattg tatcgttcgt agcatatctg cttatttttt
     6541 gttttactaa caaatttctt gtaataaata taaaatattt taaaaacttt ataattatga
     6601 taaaatttaa agtatatgac aaggagggat ttaatgagag gaagagtaat tttattaata
     6661 tcgatattat ctatatttct tgtaggatgt tcatttaata aaaaagatga aataaattta
     6721 gtagagcaag gaaaaacata tttagaaaaa cataactata aaaaagctat ggaatcatta
     6781 tcctctgcac tggaagaaga tagtactaat gagaatgcaa gagctatgta tatgcaagct
     6841 atgagaatgt caaatatgac ggagtttgaa gaattaaaaa attatgaggg tgcaatcaag
     6901 gaacttaaac ttatagagaa aatcaaaaat ggttcctctg ttattaaaga agaggcaact
     6961 aaaaagaaag aagagttaac taaattagaa aaagaacaaa acgaagcaga ggaacaaaga
     7021 aagaaaaagg caaaagatac ggctggagaa gataggtata gagttgaatc agatgcaagg
     7081 aaatcttctt atagtggaag tagtaaaaat aataaatcta gttctaaaaa taatgataaa
     7141 aaatcagata gtaataagtc tgacaataat aacagttctt ctcaaaatca agaaaagcca
     7201 aataatagta atccaacacc agcaccaact ccacaagata ctactggtgg ttcagatagt
     7261 ggtggaaatt ctcaaaactc aaataatcaa taagtataaa atatatgcat aaatttaatg
     7321 aacaaattat atattataaa aaatatctct tagcaatttt ttcttactaa gagatatttt
     7381 ttgagaaata atttaataaa taacagttaa attttaaact aaaaattaaa gtcacagtag
     7441 agataagcta ttgtaaacga ttatctatat atttatcaac ataagttttt acaacagcag
     7501 ctattggtac tgaaagaaaa actcctatga aaccaaatag agattgtccc accaaaatag
     7561 cagatattac ccatatagct cctataccaa cttgattacc cataactttt ggttctataa
     7621 aatttccatc taattgttgc aatataaata gaaatgcaat gacccatata gttttttgtg
     7681 gactatataa tatagtcatg gctattggag ggattgcacc aataaaagga ccaaaatagg
     7741 gaattatatt acctaagaat attattgaag ctaaaaataa agcattttct attctgataa
     7801 caaattgaaa tcctaaaaat gcaattatac caataataag agagtctaat attctaccaa
     7861 gtaaataatc atagaaaata tcatgagtag tcctaaaaaa ttctataatg ttatctgcct
     7921 tgtttctagc agtagaagaa tatagaaatc tcttaaatcc caatgcaatt ttttctttgt
     7981 catatataat gtatatggat agtataaatc ccattgtcat attaaatagc atagaagata
     8041 tactaagtgt atagattaag aagtttttag gaattttacc aacaaaatta cttgcttctt
     8101 ttaataaatt atctaaacta tgttgtatat gaggaattaa agtttttaga aaatctatgt
     8161 ttgacatatt tttttctata aaactatcta tataatcagt atacataggc atttcattta
     8221 tcaatctatt taatgtatta gctattgatg gaattaatag cctaatggca aaggctaaaa
     8281 taaaacctat aaatatataa gataaaaaaa tggctaaaag tctatgtgct ttgaatttta
     8341 cctcaaaaag catcacaagt ggatttaaaa gtaaagcaag taaaatagct aataaaaatg
     8401 ggctaaaaaa ctttaagaat ccttcaatac tagatataaa gtttgatgga gtattaataa
     8461 atttaaaaaa taaaattcca ataaacacga ctattaaata atattttata ttttcctttg
     8521 aaataataat cacttcctta aaatagtgtt tagtcaacta ttacatatta atagtatgtg
     8581 aaaagaaatt acaattattt aggaaaatta aataattttt ttgcttgttt ttaattaagg
     8641 tctagtatag tataataatg tagcaaaatt aacattgata aaaatattaa acacacataa
     8701 tttaagataa ggaaggatta agtatgagaa ttaataagta tatagcttct tgtggaatag
     8761 catcaagaag aaaatcagaa gaaataattc ttggaggaag aataaaggta aatggaagtg
     8821 tagtaaaaga gttatctttt aatattgatg aagaaaaaga catagtagaa tttgataata
     8881 aaaaagtaaa accaagtgaa aattatatat atatagtatt aaataaacca gagggatata
     8941 taactacagt aaaagaccaa ttcaatagac ccagtgtaat agacatactt aaagatgtaa
     9001 gggaaagagt atatccaata gggagattag attatgaaac tagtggttta ttaatactta
     9061 ctaatgatgg cgatttaaca tataagctta cccatccaaa gcatgaaatt gataaaacgt
     9121 atgtggcaag tgtgaaggga attataagtg atgatgagat aagacaattc gaaacaggac
     9181 taaaaataga agattacaca acggcacctg ccaaaataag ggtaactaaa gaaaataaag
     9241 aaaaaaatta ttcagtgtgt gaaataacta tacatgaggg tagaaataga caagtaagaa
     9301 aaatgtgcaa agctataaat catccagttt taaatttaag aaggatttct gtggggaaaa
     9361 tagtattaaa agacaccaaa gttggagaat atagatacct aacagaagat gaaataaaat
     9421 atttaaaatc aataaaataa gataaaaata aattgagaaa aaatgaaata aagttaatag
     9481 tagggagaaa tagtattatg gcatatgcaa agtatttaac taaaattaca gatataaata
     9541 aattttattt agaaaatatt ataaatgaag gggacatagt aattgatgct actatgggaa
     9601 atgggtatga tacaaggtat ctagctgaga aggttggaga aaagggcttt gtatatgctt
     9661 ttgatataca agaagaagca ataaagtcta caagaaagaa actagagaaa gaaggatata
     9721 cagatagagt aaaattgata tttgatgggc atgaaaaaat gaatcaatat ataaaagaag
     9781 aagtttcatg tgttttattt aatttgggtt atcttccaag agcgaaacat tcaattataa
     9841 ccaaaccaga tacaacttta aaggctataa agttaagttt agaaatgtta aaagaaaatg
     9901 gagtaataag cattgccata tatacagggc atgatggagg tcaagaagaa aaagattgca
     9961 tatataacct tgtcaataat ttaaatcaag atgaatttaa tgttttagaa tctaagtttt
    10021 taaatcaagt caataaccca ccacaattga ttttaattga aaagaaaaaa gcataataaa
    10081 tactaaaaaa cttgacaaga ttctattaag agttaatata tatagtgtga cctattaaaa
    10141 atactttaaa taataagtat acaacagctt attctcaaaa caaaatatac atctaaatat
    10201 gcaaaataag atagataact tttaaatgag taaaaattga aaaatttaaa agaaatattg
    10261 gataaatatt aaaaaatgca aggaaagatg gtataataaa tttaatcgaa aatactatgt
    10321 gaagtataag tataaggtac agaaaagtta gaattttatg agtttaagaa gctatgataa
    10381 aaactaagat gaaattgaga taaaaaataa aatttttaga gaaaaagaca gtgttaataa
    10441 aacaaaatag tttatataac taaaaggaga aaaaaatgga agaaacaaat gaaatgaagg
    10501 acagtaaaca tttgatatca aatatacaat ctcaatatac gagattgagt aagggtcaaa
    10561 aacttatagc acaatacatt ttaaataatt atgataaagt tgcatttatg actgcatgta
    10621 aattgggtga aaccgtagga gtaagtgagt ctacagttgt aagatttgca aatgcattag
    10681 gttatagtgg atatcctaaa ttacaagctg cacttcaaga actcataaaa aataaactaa
    10741 ctacagtaca aagagttgaa atggcacatg attattccga tgattttgca atactaaaca
    10801 aagttttaaa aagtgatata gataatataa ggtctacact agaagaaatt gacgagagag
    10861 cgtttaaaga agcttctaac aaacttttaa gagcgagaaa aatatatata cttggaatga
    10921 ggagttcttt tgtagtagct caatatttag gtttttactt agatataata cttgacaatg
    10981 ttcatataat tagaatggat atgggagatg cttttgagca gattgtcaga ataaatgaag
    11041 aagatgtaat agttgctatt agtttccctc gttattctaa gaaatcttat caaattgtca
    11101 attatgctaa ggaaaaagga gcccatgtaa tatcattaac agatagctta tttgcgccag
    11161 tagcatcact tgcagataac actcttctag ttaagagtaa tatggcttca tttgtagatt
    11221 ctctagttcc agctcttagt atttcaaatg cccttgctat atctgttgga atgaaggaaa
    11281 aagaagatat taaacagcat tttgatgatt tagagcaaat ttggaaaaga tattctgtgt
    11341 atgagtaaag tttgtatatt aataagtatt attaattatt aaaatgttca aatatagtga
    11401 tgtttggata aaatatataa aatagctgac tggcatttaa ctgacagtca gtttttttat
    11461 ttaaacaata ttttgcttaa attttaagga atatctttgt ctatttcttc taaatgagag
    11521 tatttattca tagttatttt catttattat gtttcttgtt gatgatatat ttttttatag
    11581 aaaagaaaat agttatggtt ttgtatctgt tatttttgca cttattcaat ttatttttgt
    11641 gaaacctgga aagataaaac tttaatagca gataataacc ttgagattgt aaagtaacaa
    11701 agtgaaaatg tagaaagaga aaaagaaatg gaaggaagaa aagtatatag ataaagagat
    11761 ataacacgta ttttgattta actgtataag atgaaaaatt tgatgatttt gaatagttta
    11821 aaaaattgtt aatgaaaata aaagacttgt tgagctaaag tgcgattaca taggaaggat
    11881 gcaataaaaa gaaaaaggaa tcattggaat agagaatata ataaatactt ataagaatgt
    11941 agatgctttt agtttgtaaa attatcccat ttttatttta tagtatgagt tttatgatat
    12001 aataaaaata taaaagtttt gcagtgagcg atttttgtga taaagtaggg tttaatagtt
    12061 gaaatataaa gcgttgagag tgtatgataa ctgttatcaa ttgcactatt gctcgctcac
    12121 tgcaagttta ggagaattgt atatgtataa gtattggaaa tacttaattt attttggggt
    12181 tttatattaa ctatatggaa tgtaaagaaa aaatttacta attcagtata atatttatta
    12241 tctgagtttt atattaacta tatggaatgt aaagacgtgt agagtagaca atacaggttt
    12301 ttgggtagag ttttatatta actatatgga atgtaaagtc tagttttttc tctttagaaa
    12361 aaataaaaac aactgtttta tattaactat atggaatgta aattaaaatt gtgttttctc
    12421 tttcatacac ccacttcatt agttttatat taactatatg taatataaat gttttttctt
    12481 attaaataaa gattgagtca ctttatattt aataatacat attctaaatt gattttgttt
    12541 ttatataaga gaatttgaat aatatggaaa aagatgatta ataaattatt aattagggta
    12601 taaaatgata taaatagaat aaataagggg tggatgaaat gcttgtatat aataaaagtt
    12661 tttatcctaa tgacatattt ccaagattag atttttcaaa aataaaaaaa cagttaaaat
    12721 tgatagataa tgacctgtca gattttggaa gcatatgtat aatagaaaaa gaacattata
    12781 cgataagtgt aaacagtata ggtgaaataa atgtgtatta tgatttagag tacgaaaata
    12841 aggtgtatag aatagtttat gagattgaaa agttatttaa atctcaagtt ggaaggttta
    12901 gtatatctac atacagaaat tgataattaa aaaagtagaa attaaaaaac ttaatactaa
    12961 agatatagat aaatatataa ggtaacagct agagagagtt gttacccttt ttaaatacta
    13021 agtatatatt attcttatta attttttgta aa
//
LOCUS       DACTZW010000106        12716 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.107, whole genome shotgun sequence.
ACCESSION   DACTZW010000106 DACTZW010000000
VERSION     DACTZW010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12716
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.107"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            124..525
                     /locus_tag="JAM15_16660"
     CDS             124..525
                     /locus_tag="JAM15_16660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799883.1"
                     /translation="MKKCLYCNRDIKSPNNKLAIKYDDNMNIYPCRAECKEKIEEYIA
                     KKPTYKFINILEVLLGVGGIFCFLSKWTIAAQVVLGIDALVIFLFPLAGFKMNGKLSM
                     EQTKNQSRSIAISILAFIVIITVLYFKQVGK"
     gene            568..861
                     /locus_tag="JAM15_16665"
     CDS             568..861
                     /locus_tag="JAM15_16665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HAT6799884.1"
                     /translation="MEERKLAPNNEREALIKRLKRIEGQVKGIQKMVEQERYCVDILV
                     QISAIRSAINRVGTIILENHIKGCVAESIKHDAADKTEEMIKELMDTINKFTK"
     gene            876..1316
                     /locus_tag="JAM15_16670"
     CDS             876..1316
                     /locus_tag="JAM15_16670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SoxR reducing system RseC family protein"
                     /protein_id="HAT6799885.1"
                     /translation="MNQQGFIMEIVDDRTAKLKMQRHSACAACGKCATTNSAESKEIL
                     VEVDNTIGAKVGDHVEVSMDNMNVLKAAVMAYIIPLIALLVGTIGTYYILGAIGMTTG
                     VEAISGLVGICLTIICYLYLKKNDKKFRDSREFIPVITRILIDL"
     gene            complement(1408..1881)
                     /locus_tag="JAM15_16675"
     CDS             complement(1408..1881)
                     /locus_tag="JAM15_16675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter"
                     /protein_id="HAT6799886.1"
                     /translation="MTDMSMILHFLFSGVATAGFAVFFNAPLYLLLPAGVTGGIGWIV
                     YVYLFNFTTNAVFAGFIAAALVSACSETLARKLKQPAIVFVIPGILPLIPGIGLYNTM
                     LSLIQKNYSLAMSKGTDALFLSAAIALGVLVVTSFVRTLNLLKIRKNFIPYRKSK"
     gene            complement(1881..2669)
                     /locus_tag="JAM15_16680"
     CDS             complement(1881..2669)
                     /locus_tag="JAM15_16680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HAT6799887.1"
                     /translation="MNQNEELEYKKNILKLALFVGELMIKNGAETSRVEDSVLRICRS
                     RGFYHVNIFTTPTVIIISDEKFDGFSFMKTIQSRGINLNKISLLNSFSREFVSDKEYD
                     IDNAIARLYEIQDVKPYPLWLFYSCTGIASACFACLLGGNYVLNFILTFIIAIFAAIT
                     YDKTMKISAISAFSCLVSSFLIALSGVLLVEIGILDDPKMLIVGAIMPLLPGVAFIKA
                     IRDLISGNLISGISRAFDAAMIIIAIASGVGFVLDTWYRIGGPF"
     gene            2997..4241
                     /locus_tag="JAM15_16685"
     CDS             2997..4241
                     /locus_tag="JAM15_16685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HAT6799888.1"
                     /translation="MFENLKKADPEIYESMKRELKRQQRNIELIASENIVSVPVMETM
                     GSHLTNKYAEGYSGKRYYGGCEYIDEVETLAIDRIKKIFGAEHANVQPHSGANANIGV
                     YFAMLKPGDVVMGMNLSQGGHLTHGAPVNISGQYYKFYEYGIDKDSGLIDFDEVRKIA
                     HEVKPKMIVAGASAYPREIDFKKFREIADEVGALLMVDMAHIAGLVAAGIHQNPCEVA
                     DFVTTTTHKTLRGPRGGVILCKEKYAKDIDKAIFPGIQGGPLEHIIASKAVCFKEALS
                     DEFKEYQVQVAKNAKALAEELIKRDFKLISGGTDNHLILLDLTNKNITGKAAEKRLDD
                     AYITANKNTIPFDPNGALVTSGIRLGTPAVTTRGMKEEDMAIIAEAIDLCLTYDEESK
                     ARTLVVGLTEKYPLYEEYNIMD"
     gene            4564..5661
                     /locus_tag="JAM15_16690"
     CDS             4564..5661
                     /locus_tag="JAM15_16690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-diphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HAT6799889.1"
                     /translation="MKVLILTGKFGMGHYSASNSLSEDIKAKFDNSEITIKDIFEYIM
                     PNYSDKMYKTFSILVNRGSSLYNLFYKCAENGKKDIKFTFSDYFLNKLDTLLHEVQPT
                     VVISTFPFCSQLVSRYKEKYNSNLPLITCITDISSHSEWISKNTDCYLVASKSTKEEL
                     VFKGIDESKIKVNGIPVKKEFKRIEHVNHSTKKNILIMGGGLGLLPKSEQFYKELNSL
                     EGVKTTVITGNNKKMYYKLYGRYENIEVVGYTNEVYKYMKDSDLIISKPGGITLFETI
                     YSELPILAFNPFLQQEIDNASFILNNEIGRILGKNKKYYVDEIKDLIYDDATLKEMSS
                     NMKELKKQFDNNILENILFSLDEQGACRECM"
     gene            5652..6350
                     /locus_tag="JAM15_16695"
     CDS             5652..6350
                     /locus_tag="JAM15_16695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HAT6799890.1"
                     /translation="MYVVGLIIVVALIFLVHSIIPTYYNKLLNKEVLKNMAGENEIAL
                     TFDDGPDKRYTEKLLDVLKENDIQAMFFVVAKNAEKEPEIIKRMLRENHIVGLHSLEH
                     RNAWLYSYSYVKKDFIESTNIMKNLGVDVNYYRPPWGHTNIFSNSFVKKYNLKMTLWD
                     VMAEDWEKDSTVDIIINKLMSRTKENSIICLHDAGENSGGAVGAPERTIEALKIAIPK
                     LKASGLKFVTPERM"
     gene            6353..7417
                     /locus_tag="JAM15_16700"
     CDS             6353..7417
                     /locus_tag="JAM15_16700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HAT6799891.1"
                     /translation="MISKTEKKNKCLGSVAFLVLLMGITGYFVFRGQSVESLIKSLKG
                     ASPMFILIGFAMMFIYVACEGINIYLGMKALNQKTTLLKCMGYAFIGFYFSSITPSAS
                     GGQPAQVYYMKKDDINISYSSLILLVIVVIHQVVILAYSGIMFIMEREFILNNVSGMN
                     ILLIYGVITNVALVIGVIAIIFSKKLVNNFIISITNLLGKLRIIKDVESSRKVIISQI
                     EEYVKGAQYIKQNPKLVVQILVITIVQITAMFLVPFFVYKAFHLSTYTVFEILAIQSL
                     LNIAVSSLPLPGAVGASENSFMTLFKIFFPGHLLVPAMLLSRGISFYAFVAISGLICI
                     VVHVKSSEKVKAVKKVAYVR"
     gene            7600..8304
                     /locus_tag="JAM15_16705"
     CDS             7600..8304
                     /locus_tag="JAM15_16705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6799892.1"
                     /translation="MNKEIPKKILVADDNPEIREIVEILLTGEGYEVIMATNGEEAVN
                     LVDSTIDLIILDVVMPVKTGFVACNEIREKTTAPILFLTAKTQDSDKVIGFSAGGDDY
                     LSKPFSYSELISRVKSLLRRYYIYQGKEKEREPNILKTKELCVNLDTQDVTLNGEPVF
                     LTTIEYSILILMLKNRKKVFSSENLYETIWDEQYFYTANNTIMVHIRNLRKKLEKDQK
                     NPQYIKTAWGKGYYID"
     gene            8297..9619
                     /locus_tag="JAM15_16710"
     CDS             8297..9619
                     /locus_tag="JAM15_16710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAT6799893.1"
                     /translation="MINKIKPSKLGVILLIYVVISAAVAFILNIPFYSAVESIVKDVS
                     EGKVYFKREVNQLMDNFQTYVNNNGIRADDGDDIAKWNSDNWFVSMKIYKGNKVFYDT
                     LYYPNEVPDKSEENEFYSSPMARNYEIQFSDIKANIIVVALFRFRFQNFIEAIFITFM
                     ALTFIITFLLLFSRKIKYLRKIEMGIKIVESGSLKYRIPVKGNDELSSLASSINEMSH
                     TLENQLIKEREMKNKNKDIVTSISHDVRTPLTSVICYLDLIKDHKYNSPEQLEQYIKN
                     VRSKAYQIKDLTDDLFTHFVNSGEEVSKGYEKINANEFIFQLLLDSSYTLEEKGFHIT
                     IENELYNQYHIYVDVTQFRRIFDNLCSNIIKYARKDKPIVFLIKVEDSKLLIIQKNRV
                     SNFSKNVESFGIGIKNCEKIVAYHNGSINVNSDDKEFAIEISIPAKES"
     gene            9806..11179
                     /locus_tag="JAM15_16715"
     CDS             9806..11179
                     /locus_tag="JAM15_16715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799894.1"
                     /translation="MVLTGAHYIYILFMVIILITMIMKKDTIVPCILGVFFMGLFFEK
                     NIFGAITAVFNSFIISLNELGPIILIIAIMVALSKALEANNAIQYMVRPFSRVIKNSN
                     TAFFVTGFVMLVLSWFFWPTPAVALVGAVFLPVAMRAGLPAIGVAVALNLFGHGLALS
                     TDFVIQGAPSITAGAAGVAVSYVINDGMILFWVMGIVTISMAFYTLKRDINKGMFREE
                     LKGFESEEVEEFNGKSKIATILVALGFLADIIVMYIFDLKGGDASALLGGTAVFLIII
                     INVINFGKDSLENVCENIIDGFVFGIKIFGAIIPIAAFFYMGEVAPLTGVFGKVLAPG
                     SQGLLSDIGIALSQTIPLNKFAVSGIETVVGAITGLDGSGFSGISLVGSLASVFGTAI
                     NASVGALAALGQISGIWVGGGCLVPWGLISAAAICGVSPIELAKRNFVPVITGLVVTT
                     IVAMFII"
     gene            complement(11539..12477)
                     /gene="pdaA"
                     /locus_tag="JAM15_16720"
     CDS             complement(11539..12477)
                     /gene="pdaA"
                     /locus_tag="JAM15_16720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HAT6799895.1"
                     /translation="MFRKVLHYLTLLSISIFFIVGCSNSQNNQNENQNKETQLQEDKE
                     KIDGGKDTSNVIVSDGTDKPSKATTNNDNNKLDVSSLDNTTLDWFYIPNNKHKTPEVN
                     TDIEFKFSDYDALYNGPTKDGQKTLYLTFDEGYENGYTTKILDTLKQNQVKAVFFVTA
                     PYIKENKDLVKRMVSEGHIVGNHSKTHPSMPTKTSNLKNFNDELYDVEKLYKDVTGKD
                     MVKFFRPPMGKYSEKSLAMTKNLGYKTVFWSFAYRDWDTDKQPSHEEATQKIMDNLHD
                     GSILLLHAVSKTSTEILNDFISNARKLGYEFELLEY"
BASE COUNT         4764 a         1480 c         2144 g         4328 t
ORIGIN      
        1 gtaaaagaag tagctaaaat tattcctttt atttttgttt tttgtatcta tttggtataa
       61 tagtattaga gcgtataata atttaggcaa aattttttaa ggaagactag aggagaatat
      121 aaaatgaaaa aatgtcttta ctgtaatagg gatataaagt caccaaataa taaattagct
      181 ataaaatatg atgacaatat gaatatatat ccatgtcgtg cagaatgtaa ggaaaaaatt
      241 gaagaatata tagcaaaaaa acctacatat aagtttataa atatattaga ggttctttta
      301 ggtgtgggcg gaatattttg ctttttgagt aaatggacta ttgcagccca agttgtactt
      361 ggaattgatg cactggttat atttttattc ccattggcag gatttaagat gaatggaaag
      421 ttaagtatgg aacaaactaa gaatcaaagt aggtctattg caatatcaat tttggcattt
      481 atagtaataa taactgtatt atattttaaa caagttggta agtagagcat aattgtataa
      541 gacatcatta gagtatgagg tgagtttatg gaagaaagaa aattagcacc aaacaatgag
      601 agggaagctc tcataaaaag attaaaaaga atagaaggtc aagttaaggg gatacaaaag
      661 atggtggaac aagaacgtta ttgtgttgat atattggttc aaatatctgc tataaggtct
      721 gctataaata gagtaggcac aattatctta gagaatcata taaaaggatg tgtagcagaa
      781 agcattaaac atgatgctgc tgataaaact gaagagatga taaaagagct tatggatact
      841 ataaataaat ttacaaaata aggaggcggt tagttatgaa tcaacaagga tttattatgg
      901 aaattgttga tgatagaact gcaaagttaa aaatgcaaag acattcagct tgtgctgctt
      961 gtggaaaatg tgctactaca aattcagcag agtcaaaaga aatattagta gaagtagaca
     1021 acacaattgg tgcaaaagtt ggtgaccatg tagaagtgag tatggataat atgaatgtat
     1081 taaaagcagc tgtaatggct tatataatac ctcttatagc acttcttgta ggaacaatag
     1141 ggacttatta tatattgggg gcaattggaa tgacaactgg agttgaagcc ataagtggat
     1201 tagttggaat ttgtcttaca ataatctgtt atttatactt aaagaagaat gacaaaaaat
     1261 ttagagacag tagagaattt ataccagtaa taacaagaat attaattgac ctttaagata
     1321 attataatta aaaaatagca atgtgctttt taaataaata ctcaatacgt atttgtagag
     1381 tttaagtaca ttgctatttt tatattttta ttttgatttt ctgtaaggaa taaagttttt
     1441 tctgattttc aaaagattca atgttcttac aaaagaagtt acaactaata caccaagtgc
     1501 tattgcagca cttagaaata gcgcatctgt accttttgac atagccaaag aataattttt
     1561 ctgaatcaaa gacaacattg tattatatag cccaattcct ggtattagag gaagaatacc
     1621 tggaattacg aacacaatag ctggttgctt tagttttctt gctaaagtct cactgcacgc
     1681 tgagaccaaa gcagcagcga taaaacctgc aaaaactgca tttgtagtaa aattaaataa
     1741 ataaacatat acaatccaac caattccgcc agttactcca gctggaagaa gtagatatag
     1801 tggagcatta aagaaaacag caaatccagc agttgcaaca cctgaaaata aaaaatgcaa
     1861 aatcatagac atatcagtca ttagaaagga cctcctattc tataccatgt atcaaggaca
     1921 aaaccaactc cagaagcaat tgcaataata atcatagcag catcaaaagc acgagaaatt
     1981 cctgatatta aattccctga tattaaatct ctaatagctt ttataaaagc aactcctggg
     2041 agtagtggca ttatagcgcc gactataagc attttagggt catctaaaat gcctatttca
     2101 actagtagaa ctcctgaaag tgcaattaaa aaagaagata ctaaacagga aaatgcagat
     2161 attgcactta tcttcatcgt tttatcataa gtaattgcag caaagattgc tattataaac
     2221 gtaagtataa aatttaatac ataattccct ccaagcaaac aagcaaaaca agcagatgca
     2281 attcctgtac aagagtaaaa taaccataaa ggataaggtt ttacatcttg gatttcataa
     2341 agacgtgcaa tggcattatc aatatcatac tctttgtcac taacaaattc tcgagaaaaa
     2401 ctgtttaata aagaaatctt gtttaagttt atacctcttg attgaatcgt tttcataaac
     2461 gaaaagccat caaatttctc atctgaaata attattactg taggagttgt aaaaatattt
     2521 acatgataaa accctcttga cctgcatatt ctaaggacac tgtcttcaac cctagatgtt
     2581 tcagctccat tttttatcat cagttcccct acaaatagag ctagttttag aatatttttc
     2641 ttatattcaa gttcctcatt ttgattcata aatacacctc caaattaaaa aacgtaatat
     2701 tgaaattata tcaaattttt aagtaatatt ccttaatatc tatataaata tattatcttt
     2761 tttttgtttc aaaatagtca catttaaatt atatccaatt aaaagaatta gacaatatta
     2821 tttattatat tttaacttaa aaataaagaa agtaactatg ttaaatatgg aaaaatggca
     2881 aaacacttga ctattaattg gtaaaggact ataataataa attatcatat tgataaaaac
     2941 gaaaattatg aaatgtctgt aaaaataaaa tttaaataat aactaggagg agtaatatgt
     3001 ttgagaactt gaaaaaagcg gaccctgaga tttatgaaag tatgaaaaga gagttaaaaa
     3061 gacaacaaag aaatattgaa ttaatagcat ctgaaaacat agtatcagtt ccagtaatgg
     3121 aaactatggg aagtcatctt acaaataagt atgcagaagg ttactcaggc aaaagatatt
     3181 atggtggatg tgaatacata gatgaagttg aaactcttgc aatagataga atcaaaaaaa
     3241 tatttggagc agaacatgct aatgttcaac ctcactctgg agcaaatgca aatattggtg
     3301 tatattttgc tatgttaaaa ccaggtgatg ttgttatggg aatgaattta tctcaaggtg
     3361 gacatttaac tcatggtgct ccagttaata tttctggtca atattataaa ttttatgaat
     3421 atggtataga taaagacagt ggacttatag attttgatga agttagaaag atagcacatg
     3481 aagtaaaacc taaaatgata gttgcaggag caagtgcata tcctagagaa atagatttta
     3541 aaaagtttag agagatagct gatgaggttg gagcattgct tatggtagat atggctcata
     3601 tagcaggtct tgtggctgct ggtattcacc aaaatccatg tgaagtggct gattttgtta
     3661 caacaacaac tcacaaaact ttaagaggac ctcgtggggg tgttattctt tgtaaagaaa
     3721 aatatgctaa agacatagac aaagcaatat tccctggtat tcaaggtgga cctcttgaac
     3781 atataattgc ttctaaggca gtttgcttta aagaagcttt aagtgatgag tttaaagaat
     3841 atcaggtaca agttgctaaa aatgcaaaag ccttagctga agaacttatt aaaagagatt
     3901 ttaaattgat ttctggaggt acagataatc atttaatact attagatttg actaataaaa
     3961 atataactgg taaagcagca gaaaagagat tggatgatgc ttatataaca gctaataaaa
     4021 atacaattcc atttgatcca aatggtgctc ttgttacaag tggaataaga cttggtactc
     4081 cagctgtaac tactagaggt atgaaagaag aagatatggc aataatcgct gaggctatag
     4141 acctatgttt aacttatgat gaagaatcta aggctagaac attggttgtt ggtttaactg
     4201 aaaaatatcc tttatatgaa gaatataata ttatggatta attataaaga acaactaaat
     4261 aaaatacatt taaataatta caatgattgt gtatgtattt gaatatattt agatataaaa
     4321 aaggtgtctc aaaatgaact ttttagttta tgaggcactt ttttgtatgg aatcgaacat
     4381 atttgtgtta tttaaataat aaaaaatatg gttatctcta tttttagatg gtctctttgt
     4441 attttttaat taaaacttta agatttctta agaattatac taggtttttc taaagattta
     4501 aagtctatac ttataagtat agtaatcata tgaaaagaaa agctttaacg aggagggaat
     4561 cttatgaagg tattaattct tacaggaaaa tttggtatgg gtcattactc agcatcaaat
     4621 tctttaagtg aagatataaa agcaaaattt gataattcag aaataacaat taaagatata
     4681 tttgaataca ttatgcctaa ctattcagat aaaatgtaca agactttttc tattcttgta
     4741 aatcggggaa gtagtcttta taatttgttt tataaatgtg ctgaaaatgg aaagaaagat
     4801 ataaaattta ctttttcaga ttatttttta aataaattag atacattact tcatgaagta
     4861 caaccaacag tagttatttc aacttttcca ttttgttctc aattagtatc aagatataag
     4921 gaaaaatata actcaaatct tcctttaata acatgcataa ctgatataag tagtcactca
     4981 gaatggatta gtaaaaatac agactgttat ttagtagcta gtaaatctac taaggaagaa
     5041 cttgttttta aaggaataga tgaatctaag attaaagtta atggtattcc agtaaaaaaa
     5101 gaatttaaaa gaatagaaca tgtaaatcat tcaactaaaa aaaatattct tataatgggt
     5161 ggaggattag gattactgcc taaatcagaa caattttaca aagaattaaa tagtttagaa
     5221 ggagtaaaaa ctactgtaat aactggtaat aataaaaaaa tgtactataa actatatggt
     5281 agatatgaaa atatagaggt agtaggttac accaatgaag tatataaata tatgaaagat
     5341 tctgacctta ttatttctaa accaggtgga ataacactat ttgaaacaat ttattcagaa
     5401 cttccaatat tggcatttaa tccattttta caacaagaga tagataatgc tagttttata
     5461 ttaaataatg aaattgggag aatacttggt aaaaataaaa aatactatgt agatgagata
     5521 aaagatttaa tttatgatga tgctactctt aaagaaatga gcagtaacat gaaagaatta
     5581 aaaaaacaat ttgacaataa tatcttagag aatattttat tttcacttga tgaacaagga
     5641 gcgtgtagag aatgtatgta gtaggtttaa ttatcgttgt tgcattgatt tttttagtcc
     5701 attcaattat acctacatac tataataaac tattaaataa agaggtatta aaaaatatgg
     5761 ctggagaaaa tgaaattgca cttacatttg atgatggtcc agataagaga tatacagaaa
     5821 aattactaga tgtgttaaaa gaaaatgata tacaagctat gttttttgta gtagcaaaga
     5881 atgctgaaaa agagcctgaa attataaaaa gaatgttgag agaaaatcat atagttggtt
     5941 tacattcatt ggaacacaga aatgcatggc tttatagtta tagttatgtt aaaaaagatt
     6001 ttattgaaag tacaaatata atgaaaaatt taggtgtaga tgtaaactac tatcgtccac
     6061 catggggtca tactaatata ttttcaaatt catttgttaa aaaatataat ctaaaaatga
     6121 ctttgtggga tgtaatggca gaagattggg agaaagatag tacagtagac attattataa
     6181 acaagttaat gagtagaaca aaagaaaatt ctataatttg tttacatgat gcaggtgaaa
     6241 attcaggtgg tgcagtaggt gcacctgagc gtactattga agctttaaag atagctattc
     6301 caaaacttaa agccagtggt ttaaagttcg taacaccaga aaggatgtag ttatgataag
     6361 taaaactgaa aagaaaaata aatgcctagg tagtgtagct tttttagttt tactaatggg
     6421 cataacagga tattttgttt ttagagggca gtcagttgaa tcattgataa aatcattaaa
     6481 aggtgcaagc cctatgttta tactaattgg atttgcaatg atgtttatat atgttgcctg
     6541 tgaaggtata aatatatact taggtatgaa agctttaaac caaaaaacta ctcttttaaa
     6601 atgtatggga tatgctttta ttggatttta ttttagttct attacgcctt cagcatcagg
     6661 tggtcaacca gcacaagttt attatatgaa aaaagacgat ataaatatat catattcttc
     6721 acttatacta ttagtcattg ttgttattca ccaagtagtt atactggcat atagtggaat
     6781 aatgttcatt atggaacgtg agtttatatt aaataatgta agtggtatga acattttact
     6841 aatatatggt gtaataacaa atgttgctct tgtcattgga gtaattgcaa ttatattttc
     6901 aaaaaaactt gtaaacaatt ttataatatc aataacaaat ttattaggta agttaagaat
     6961 aataaaagat gttgaaagtt caagaaaagt tataatatct caaattgaag agtatgttaa
     7021 aggtgctcaa tatataaagc agaatccaaa acttgtagtc caaattttag tcataactat
     7081 tgtacaaata acagctatgt ttttagttcc tttctttgta tacaaagctt ttcatctatc
     7141 aacatatact gtatttgaga tattagcgat acaatccttg cttaatattg ctgtttcttc
     7201 attaccattg ccaggggctg ttggagcttc tgaaaatagt tttatgacat tatttaagat
     7261 atttttccct ggtcacttat tagttccggc aatgttactt agtaggggaa taagttttta
     7321 tgcatttgta gctataagtg gattgatatg tatagtagta catgtaaaat cttctgaaaa
     7381 agtaaaagca gtgaaaaaag ttgcttatgt aagataatat tatatagatt atttttatta
     7441 atatgtcaat ttgtgtgtac attttaatta agttttaaac atgtttacag gagtataaac
     7501 tattaaaaca tgtgacattg ctaagctttt gctaataaag tataatattt tatatagttt
     7561 gaaatattta agaaatatag caaaaaaagg agcttggtga tgaataaaga gattccaaaa
     7621 aaaattttag tagctgatga taatcctgag attagggaaa tcgtagaaat acttttaact
     7681 ggtgaaggtt atgaagttat tatggcaacg aatggagaag aagctgtaaa cttagtagat
     7741 agtacgattg atttgattat tttggatgtt gtaatgcctg taaaaacagg atttgttgca
     7801 tgtaatgaaa ttagagaaaa aacgacagca ccaatattat ttttaactgc aaaaactcaa
     7861 gactctgata aagttattgg attttcagca ggaggagatg actatttatc aaagcctttt
     7921 tcatattctg aactaatttc aagggttaaa tcgctactta gacgttatta tatataccag
     7981 ggaaaggaaa aggaaagaga gccaaatata ttaaaaacaa aagagttatg tgtcaattta
     8041 gatactcaag atgttacact aaatggagaa cctgtgtttt tgacaactat agaatatagt
     8101 atattaattc ttatgttgaa aaatagaaaa aaagtttttt cgtctgaaaa tttatatgaa
     8161 actatttggg atgagcagta tttttatacg gcaaataata caataatggt tcatattaga
     8221 aatttaagaa aaaagttaga aaaagaccaa aaaaatccac aatatataaa aaccgcatgg
     8281 ggaaaggggt attatattga ttaacaaaat taagccatct aagttgggag ttatactatt
     8341 gatatatgta gtaatctcag ctgcagtggc tttcatttta aatataccat tttactctgc
     8401 tgttgaatct atagtaaaag atgtatcaga agggaaagta tattttaaaa gagaagtaaa
     8461 tcaacttatg gataattttc aaacttatgt gaataacaat ggtataagag cagatgatgg
     8521 agatgatata gcaaaatgga atagtgataa ttggtttgtt tctatgaaga tatataaagg
     8581 aaataaggtt ttttatgata cattatacta tcctaatgaa gtacctgata agagtgagga
     8641 aaatgagttt tatagcagtc ccatggctag aaactatgag atacaatttt ctgatattaa
     8701 agctaatata attgtagtag ctttatttag atttagattt caaaatttta tagaagcaat
     8761 ttttattaca tttatggcac ttacatttat tataacattt ttactgttgt ttagtagaaa
     8821 gataaagtac ctaaggaaaa tagaaatggg tataaagata gtagagagtg gcagtttaaa
     8881 gtatagaatc ccagtaaaag gtaatgatga attatcatca cttgcatcta gtattaatga
     8941 gatgagtcat acattggaga atcaacttat aaaagaaagg gagatgaaga ataaaaataa
     9001 agatatagta acttcgatat cacatgatgt tagaactcca ttaacgtcag taatttgtta
     9061 tttagatttg atcaaagacc ataaatacaa tagtcctgag caattggaac aatacataaa
     9121 aaatgtaagg tctaaagcat atcaaataaa agatttaaca gatgaccttt ttacgcattt
     9181 tgttaattct ggagaggaag tttcaaaagg gtatgaaaaa ataaatgcta atgaatttat
     9241 ttttcaatta cttttagata gttcatatac attggaggag aaaggatttc atataacaat
     9301 agaaaatgaa ctttataacc aatatcatat ttatgtagat gttacacaat ttagaaggat
     9361 atttgataat ttatgttcta atataataaa atatgctagg aaagataagc ctatagtatt
     9421 tttaattaaa gtagaggatt ctaaattact aattatacaa aaaaatagag taagtaattt
     9481 ttctaagaat gtagaaagtt ttggaattgg tataaagaat tgtgagaaaa tagttgcata
     9541 tcataatgga agcataaatg taaattcaga tgataaagaa tttgctattg aaatatctat
     9601 tccagcaaaa gaatcataaa aatttaaatt atatattgtg taattgctat tatatattgt
     9661 gtaattgctt atgtaaaatt ctatgaagca ggaagcatgt gactttagtt atgggatgtt
     9721 caatattgtg tacctctagg caagtaacaa gtttacttac aagaccatat aatattatta
     9781 tcttaaaaaa aggggacata ataatatggt tttgacagga gcacattata tttacattct
     9841 atttatggta attatattaa ttactatgat tatgaaaaag gatacaatag taccatgtat
     9901 attaggtgtt ttttttatgg gattgttctt tgaaaaaaac atttttggtg ctataacagc
     9961 agtgtttaac tcttttatta tatctttaaa tgagttgggt ccaattatct tgattatagc
    10021 tattatggtt gcattatcta aagccctaga agccaataat gctatacagt atatggtgag
    10081 accattttcg agagttataa aaaattctaa tacagcattt tttgtaactg gatttgttat
    10141 gttagttctt tcttggtttt tctggccaac tccagctgtt gccttagttg gagctgtgtt
    10201 tttacctgtt gctatgagag ctgggctacc agcaattggt gttgcagtag cattaaattt
    10261 atttggtcat ggtcttgcct tgtctacaga ctttgttatt caaggagctc caagtataac
    10321 agctggtgca gcaggtgttg cagtatcata tgttataaat gatggtatga ttttgttttg
    10381 ggtgatggga atcgtaacca tatctatggc attttataca ttaaaaagag atattaacaa
    10441 aggaatgttt agagaagaac taaaaggttt tgaaagtgaa gaagtagaag agtttaatgg
    10501 aaaatctaaa atagcaacta ttttagtagc tctgggattt cttgctgata taattgttat
    10561 gtatatattt gacctaaaag gaggagatgc atcagctctt ttgggtggaa cagcagtatt
    10621 tttaataata attataaatg ttataaattt tggcaaagat agtcttgaaa atgtatgtga
    10681 gaatataatt gatggttttg tgtttgggat aaaaatattt ggagcaatta taccaatagc
    10741 agcatttttc tatatgggtg aagttgcgcc cttgacaggt gtatttggaa aagtattagc
    10801 accaggttca caaggtttat tatcagatat aggcatagct ctttctcaaa caataccact
    10861 taataaattt gccgtatcag gtatagaaac tgtagtgggg gcaataactg ggcttgatgg
    10921 ttctggattt tctgggattt cattagttgg ttcacttgcc tctgtatttg gaactgctat
    10981 aaatgcaagt gttggtgcat tagctgcatt aggacaaatc agtggtatat gggtaggtgg
    11041 aggctgtcta gttccttggg gtcttatttc agcagcggca atttgtgggg ttagtccaat
    11101 agaattggca aagcgaaact ttgtcccagt tataaccgga ttggttgtaa caaccatagt
    11161 agcaatgttt attatttaat aaatcgaata aatctttaat tgtacaaatt aaaaatagat
    11221 gtgtagctat aatttattat aattgtttta ctaattttaa gccatacatc tatttttatt
    11281 gatattttta ttagtattct ttaataaaat aatatttttc attatactat acataacatc
    11341 taaaatactg ttatctatgt ttaatatctt gccaaatttt ttgatgtttt attaccctgt
    11401 cccaccaaca tatataagct atcgcaagtt ttttacctat actatcacca aacaaaaatt
    11461 ttaattttaa tttattattt tataatctat attatattaa ctatattagt ttgtagactt
    11521 tagatgtaat tctaaatatt aatactccaa gagttcaaat tcatatccta gttttcttgc
    11581 atttgatata aaatcattta aaatttctgt actagttttg gaaactgcat gtagtaacaa
    11641 gatagaacca tcatgtagat tatccattat tttttgcgtt gcttcttcat gtgatggttg
    11701 tttatcagta tcccagtctc tgtatgcaaa actccaaaat acagtcttgt atcctaaatt
    11761 tttagtcatt gccaagcttt tttctgagta ttttcccata ggaggtctaa aaaatttaac
    11821 catatctttc ccagttacat ctttatataa cttttcaaca tcatataatt cgtcattaaa
    11881 gttttttaga ttgcttgttt ttgttggcat agatggatgg gttttactat gatttccaac
    11941 tatatgtccc tcagaaacca ttctttttac taaatcttta ttttctttta tatatggagc
    12001 tgtaacaaaa aaaactgctt taacctggtt ttgttttaga gtgtcgagta tctttgtagt
    12061 gtatccattt tcataacctt catcaaatgt aagatatagt gttttttgac catcttttgt
    12121 aggtccattg tatagggcat catagtcaga aaatttaaat tcaatgtccg tatttacttc
    12181 tggtgtttta tgcttattgt ttggtatata aaaccaatca agagtagtgt tatctaaaga
    12241 agatacatct aatttattat tatcattatt agtagtggct tttgatggtt tatctgttcc
    12301 gtctgaaact attacattgg aagtatcctt accaccatct attttttcct tatcttcttg
    12361 taactgtgtt tccttatttt gattttcgtt ttgattgttt tgtgaatttg aacatccaac
    12421 aataaaaaaa atagaaatag aaagtagtgt taaataatgc aatacttttc taaacatttt
    12481 gaagctcctt tctaaattaa taataattgc atatagtatt attataattg gaaattacta
    12541 ttaataatag ttatatcttt aaaaataaag tcacaatagt atgacaaagg gtgaataatc
    12601 aataaattta aaaaaaaatg aaaaaaatag ttgaccatat tatgagaaga tgttattata
    12661 ataaatgtgc tcaacaagaa gtaacaaaat aacaagcaca aagaagttaa ttgaat
//
LOCUS       DACTZW010000107        12332 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.108, whole genome shotgun sequence.
ACCESSION   DACTZW010000107 DACTZW010000000
VERSION     DACTZW010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12332)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12332)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12332
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.108"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            240..1067
                     /locus_tag="JAM15_16725"
     CDS             240..1067
                     /locus_tag="JAM15_16725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HAT6799896.1"
                     /translation="MDLSKKVKILENASDGKSEFEILEFEKLEGASSPLMAMGLYFAR
                     EAGLKARQIKIKLNNSSIKTEAGALYYYKGNISSETKIGGVGGLFKKGISGALTNESM
                     MKPVYKGTGEVYLEPSFRHYLFMSLDNDSIIVDKGLFYCCSDTIEVKAFTQKNFSSAL
                     LGGEGFFQIELSGTGVIVLECVVPQSEIVEYELKNGEELKVDGNFAIARTSGVNFSVT
                     KSDKSLIGSALNGEGFLNTFTGNGTVWLAPTQVMYEKLSFGAMPTNDNMNNKVSKQK"
     gene            2065..2529
                     /locus_tag="JAM15_16730"
     CDS             2065..2529
                     /locus_tag="JAM15_16730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAT6799897.1"
                     /translation="MNLNKVKFTEEHAIEVTNWKYEGKYSIYNLPPWEEIKKKNFSLS
                     KEDKRKNFISFINDNKELIGFINLLDEGSYVFFGIGIKPDYCGMGIGKEIISLGLQEC
                     RNKYSTKPIVLNVRTWNMRAVKCYKSQGFKIVETQVQKTHLGDGEFFVMRYQ"
     gene            complement(2796..3440)
                     /locus_tag="JAM15_16735"
     CDS             complement(2796..3440)
                     /locus_tag="JAM15_16735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6799898.1"
                     /translation="MFGQSFQNCLVLIKENFKLSTLTNLICSIILLCMIPLIQGVANL
                     DRISTAICLENYVAIIGIVMLVPVFSLEQSKEIDEIVSSKSLSQVIVQLIRILMSIIG
                     IVVLIIGFVNVLIYLGCNFPVVEYIIGSFASAMFIGSLGMFFSNLFNNTIIGYMISIG
                     YLILNMMTKGKYVGKFFIMSMSQGSFDEKYWLILGSVVLIIASLLIKPIKRKIR"
     gene            complement(3370..4659)
                     /locus_tag="JAM15_16740"
     CDS             complement(3370..4659)
                     /locus_tag="JAM15_16740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6799899.1"
                     /translation="MNLFIKECKNILKSMVYYIFIVVLVFFYISQLGSSVSNDVSKNI
                     PNDGNPLVAPQKVENIDEYYSVHNQYPYGQKESMKTEKVIPNATINLIREYQKNTYTT
                     YPTGVVKYIKLDQNKTKTIEKYIEEITGKSISEINLIWKTDESIKIDYSKVSLERFEE
                     IMQRVDDILGGGSAYAFDKLQRFGVVPVTYDEAMKNYNYTIQKDKVSNGYARIFCDYI
                     GIVLSIFPVFVAVFMSLKDKRSRMREIIYSKQVSSCKIVLSRYFALVFMMILPVLILG
                     MKDLLPLIFFAKDKGISIDNLAFIKYTLWWILPTLMIVTAVGMSITILTDTPVAIIVQ
                     LIWWLYSINSTGLKGDYSTMGLMIRHNSVLNGDIIIQNFNQIMINRIVISLGALVLVL
                     LAIFLYEQKRRGNLDVWAKFSKLFSSNKRKLQIKHFN"
     gene            complement(4656..5528)
                     /locus_tag="JAM15_16745"
     CDS             complement(4656..5528)
                     /locus_tag="JAM15_16745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6799900.1"
                     /translation="MEMKIAVSNLSKRFGKKQALDNINLEIDSGMFGLLGRNGAGKTT
                     FMRILATLLSKTEGSIHMCGVPIENTKEIRNMVGYLPQDFSMYPNMTVYKAMDYLAVL
                     SDIPLRKRRKIIAKLLSKVNLTNYQNVKVKSLSGGMNRRLGIAQALIHNPRVLIVDEP
                     TAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEATCENVAILDSGKVIYNGSTEA
                     LAKLAEGKVYSIEVDKKDIENIKSRFIVIGMLIHGGKAILRIISDDKPFETAVNCNPT
                     IEDGYMLIMGGDNI"
     gene            complement(6058..6549)
                     /locus_tag="JAM15_16750"
     CDS             complement(6058..6549)
                     /locus_tag="JAM15_16750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbM family protein"
                     /protein_id="HAT6799901.1"
                     /translation="MGMIGCYTKISEENVFKLQQAEENLQDFVFEDANENSTINIDKA
                     WHAIHFTLTGCPFGGDDENIFSKLVLSGNILMEIDGEFPVMLITANDVKKLSKAMNSL
                     EEQAFRKRFNINEMLENNIYPVMNDESEDDFFEYVWANLIELKKFIQEASDDGLAVIF
                     FIM"
     gene            complement(7600..9741)
                     /gene="rnr"
                     /locus_tag="JAM15_16755"
     CDS             complement(7600..9741)
                     /gene="rnr"
                     /locus_tag="JAM15_16755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HAT6799902.1"
                     /translation="MIPGLKESLLGLINESAYNPLKKEELAEIFDIHSSEMPMFYNFL
                     NELEEDGYICFTKKGKIVSPNQMGYFVGKFVSHKKGFGFVESDVEYTQDLFISSDNIN
                     GAMHNDRVMAEIVVPATEEKRAEGRIVKVIKREITRIVGTFQSSKTFGFVTPDNKKFT
                     KDIYIPKKHFSGAVDNDKVVCEITVWPQEDRKPEGKIIEILGQKGERGVEIDSIIREH
                     GLPEEFPKKVLQEAEAEAVAVEIPQEEIKRRRDLRDLNIFTIDGDDAKDLDDAISIEV
                     LPNGNFKLGVHIADVTHYVREKNKLDKEALKRATSVYLVDKVIPMLPKTLSNGVCSLN
                     PFEDKLTLSIFMEIDHKGNVVKHEICESVINSKARMTYTEVSDILEKDDEKLKKTFEH
                     VVEDFKNAEILAKILMSRREKRGAIDFNFPEAKIILNGKGEVVDIKPYERRISNKIIE
                     EFMLISNETIAEHFYWMGIPFVYRIHETPSLEKMEELSKFISTFGYIIKGDKEEVHPK
                     ALQGIIEKIKGKKEEGAISTIMLRSLKQAKYSPECSGHFGLAAKFYCHFTSPIRRYPD
                     LQIHRIIKESLNNKISGKRQEQLTTIVDYASVQSSEKERKAELAERDVHDFYKALYMK
                     DKVGQEFEGVVSSVTSFGIFVELDNTIEGLIRLANMNDDYYIYDESSYSVLGERTKKS
                     YKIGDLVKIKVESVNVDFKEIDFEIVEKIEE"
     gene            10337..10951
                     /locus_tag="JAM15_16760"
     CDS             10337..10951
                     /locus_tag="JAM15_16760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HAT6799903.1"
                     /translation="MEEVIAKIITIENGFKEIENIAKKIVKNNDSKKCYYLSIYLYRS
                     EYYQVRELAVFILGFISVTISEALLFLKDNVSKDENWRVQEILAKSFDYYCSEVGYEK
                     ALPVIKEWLNSDSPNIKRAVTEGLRIWTSRDYFKSNPDVAISLLSSLKEDDSEYLRKS
                     VGNALRDISKKYPDLVKKELDSWDISNKKVEFVYKLASKCILAK"
     gene            10969..11331
                     /locus_tag="JAM15_16765"
     CDS             10969..11331
                     /locus_tag="JAM15_16765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6799904.1"
                     /translation="MKLRDEYTCPLELTHDMIKGKWKSIILWRLRIGPTSLSKLEKEI
                     NGINQKMLLEQLKELIEFGLVDKKTYKGYPLKVEYSLTPIRGKQILDALAIMQDIGIS
                     FMLDNGMEDILKEKGVLK"
     gene            11437..11934
                     /locus_tag="JAM15_16770"
     CDS             11437..11934
                     /locus_tag="JAM15_16770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006785857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhB/YbcL family Raf kinase inhibitor-like
                     protein"
                     /protein_id="HAT6799905.1"
                     /translation="MKVTSTGIVNGVIEDKYGKRGTQFNEGGMPTYSLPLKFEDAPKN
                     TVSFAVFLEDKDSVPVCGFAWIHWLAVNITKDELNENESVTATDFVQGTTSWHGKLGG
                     LDRLEASVYGGMAPPDRPHVYEIHVFALDTILDLEKGFYMNEFFKAIEGHILDTFTLK
                     GSYSN"
BASE COUNT         4342 a         1743 c         1443 g         4804 t
ORIGIN      
        1 ataattttaa catgcccata aaatataata cccacaaatg ataaataata ctcaaaatat
       61 ctattgaaat aactatacat ccttaaataa cttaacttaa atctaaacat ttcaaaaact
      121 tcttaaaaat atgtaaaaat ttgatgataa agtagcgatt ttttcaaaaa aaatgtaata
      181 tagagttata tcttataata ttttagagat aaattttatc atagcgggga gaaatttgta
      241 tggatttaag caaaaaagta aaaattttag aaaatgcatc agatggcaaa agcgaatttg
      301 aaatattaga atttgaaaaa cttgagggag cttctagccc attaatggca atgggattat
      361 attttgctag agaagctggt ttgaaagcta gacaaattaa gataaaatta aataattcat
      421 caataaaaac agaagctggt gcattatact attataaagg aaatatatct tctgaaacta
      481 agattggtgg tgttggaggt ctttttaaaa aaggaatatc aggagcactt actaatgaat
      541 caatgatgaa acctgtatac aaaggtactg gagaagttta tttggaacct tcttttagac
      601 attatttatt tatgagtctt gataatgatt ctataattgt tgataaagga ttattctatt
      661 gttgctctga tacaatagaa gtaaaagcat ttacacaaaa gaacttctca tctgctttac
      721 ttggtggtga aggcttcttc caaatagaat taagtggtac tggtgtaatc gttctggaat
      781 gtgttgtacc tcaaagtgaa attgtagagt atgaattgaa aaatggtgaa gaattaaagg
      841 tggatggtaa ctttgcaata gcaagaacat ctggtgttaa tttttctgtt acaaaatcag
      901 ataaatcttt aattggttct gctttaaatg gtgaaggttt cttaaataca tttactggta
      961 atggtacagt ttggctagct ccaactcaag taatgtatga aaaactaagt tttggagcaa
     1021 tgcctactaa tgataatatg aataataaag tttctaagca aaaatagttg ttttataaat
     1081 atttattaaa tcattattga ttttataagg tcactataaa ttttattaga ttattattat
     1141 aaaatcagag tgtggaaatg tttatgtgta ttctttaaat aaaaatttcc acattctgta
     1201 aggttattat acttgatata taaaattcaa tttaggaaca tagtctaaca tttataaaca
     1261 tattaaggta atgatttctc ttggtaatta ttctcatatc ttattctttg attatattta
     1321 tcttattcct agcccttatg tcatattata tttcttatct tattatttat aattagcatt
     1381 aacttatcta aaatcttgta tttttttaat agtaaagttt acatctatat taatttcata
     1441 aaacaatcaa ggtagtcaag agattcaact ttatttgatt ttaaaaattt aagtgaattt
     1501 gttcttatac acatcttttt aaaattatat ctgtagaaaa tatcatttag agctataatt
     1561 aaattattaa attttagaaa atttattaaa aaatataagt taaattaata tttttaaaga
     1621 ttctttttta taactactag aatactaatt tagtagttat tgtatctcta aagtttaagc
     1681 atggatagat atacatttga taatttgcct ataatttacc tactacttgg agtattggag
     1741 caaatacaat atattaataa taagttccta aaaccaataa attaactaat acacataaag
     1801 atattgatgt tgattataca actataataa acagatttaa cagaatttaa tcaagctaag
     1861 aaattacata tatcgtgatg tttttgaatt agaaggtaat tcaaaattag tttatagtct
     1921 tctgtgaatc caataaaaag tacagggtac aagaattgtt agtaaaattt ttaaagattt
     1981 tatggataga tataaatagt tttacttatt ttgtaaaatt ttaaaatacc attaattacc
     2041 ttaaatattt taataggagg acatatgaat ttaaataaag ttaaatttac tgaagaacat
     2101 gctattgaag ttactaattg gaaatatgaa ggtaaatatt caatatacaa cctacctcca
     2161 tgggaggaaa ttaaaaagaa gaatttttca ctatcaaaag aagataaaag aaaaaatttt
     2221 ataagtttta taaatgacaa taaagaattg ataggtttta taaacttatt ggatgaagga
     2281 agttatgtat tctttggtat tggtataaaa ccagattatt gtggaatggg aattggcaaa
     2341 gaaataatta gcctaggatt acaagaatgt agaaataaat atagtactaa accaattgta
     2401 ttaaatgtaa gaacctggaa catgagagct gtaaaatgtt ataagtctca aggatttaaa
     2461 atagttgaga ctcaggtaca gaaaacgcat ttaggggatg gagaattttt tgttatgagg
     2521 tatcaatagt ttataacact agtcatattg ctaatatgac aattaaaatg aaaaaataca
     2581 tgtgtgtatg tcatagcaat aagtgtcttt gaaatataaa tttgagagcc tttgataaaa
     2641 ttcggtatac atatatattt tatactacgg atatataaat ctatctacat acataaagag
     2701 attgtaagta ggtttgtgta tataaaaata aatttatatt tcataaatgt actttttatt
     2761 tgtattacct ttattttatc taagctctca ttttattacc taatcttcct ttttattggt
     2821 tttattaaga gagatgcaat tatcaacaca acacttccaa gtatcagcca atatttctca
     2881 tcaaaactac cttgactcat agacattata aaaaattttc caacatactt gcctttagtc
     2941 atcatattta aaattaaata tcctatagat atcatgtaac ctatgattgt attattaaat
     3001 aaatttgaga aaaacattcc taaacttcct ataaacatag ctgatgcgaa acttccaata
     3061 atatactcaa ctactggaaa attacatcca agatatatta aaacatttac aaaacctatg
     3121 attaatacca ctatacctat aattgacatc agtatcctaa ttaattgtac aataacttga
     3181 gataatgatt ttgaagatac tatctcatca atttcttttg attgctctag cgaaaataca
     3241 ggtaccaaca ttactatccc tattattgca acataatttt ctaaacatat agctgttgaa
     3301 attctgtcta aattagctac tccttgtatt agaggaatca tacatagcaa tataattgaa
     3361 catattaaat tagttaaagt gcttaatttg aagttttctt ttattagaac taaacagttt
     3421 tgaaaacttt gcccaaacat caagattccc ccttcttttt tgctcatata agaatatagc
     3481 taacaaaaca agcaccaatg ctcccaagct tatcacaatt ctattaatca taatttgatt
     3541 gaagttttgt ataataatat ccccatttaa tacactatta tgtcttatca ttagccccat
     3601 tgttgaataa tcacctttga gtcctgtaga atttatactg taaagccacc aaattaattg
     3661 cacaataatt gctactggtg tatctgttaa tatagtaata ctcattccta cagctgtaac
     3721 tatcataaga gttggtagta tccaccataa tgtatatttt ataaatgcta agttatcaat
     3781 agatatacct ttatctttag caaagaaaat caaaggaagt aaatctttca tacctaaaat
     3841 taatacaggc aatatcatca taaagacaag tgcaaaatat cttgataaaa ctattttgca
     3901 tgaagatact tgttttgaat aaataatctc tctcattctt gaacgcttat ctttaagtga
     3961 cataaaaact gccacaaata ctggaaatat acttaaaact atacctatat aatcgcaaaa
     4021 aattcttgca tacccattac taactttatc tttttgtatt gtatagttgt aattcttcat
     4081 agcttcatca taggtaactg gaactactcc aaatctttgt aacttgtcaa aagcatatgc
     4141 agaccctcct cctaaaatgt cgtctactct ttgcattatt tcttcaaatc tttcaagaga
     4201 tactttagaa taatctattt ttatactttc atcagttttc caaattaaat ttatttcgct
     4261 aatactttta ccagttattt cttctatata tttttctatg gtcttcgttt tattttggtc
     4321 taattttata tacttaacta cccctgttgg atacgttgta tatgtgtttt tttgatattc
     4381 tctaattagg tttatagttg catttggaat gaccttttct gttttcatag attctttttg
     4441 accatatgga tattgattgt gtacagagta atattcgtca atattctcta ctttttgtgg
     4501 agcaactaat ggatttccat cattaggaat atttttactt acatcatttg aaactgaact
     4561 tccaagttga gaaatataga aaaaaactaa aactacaata aaaatataat ataccatact
     4621 ctttaatata tttttacatt cttttataaa tagattcata tattatctcc tcccattata
     4681 agcatatagc catcttcaat agttggatta caatttactg ctgtctcaaa aggtttatca
     4741 tctgatataa tcctaagtat agcctttcca ccatgaatca acattcctat aactataaat
     4801 ctacttttta tattttcaat gtctttttta tctacttcaa tactatatac tttcccttca
     4861 gctagttttg ctaatgcttc tgttgagcca ttgtatatga cttttccact atccaatata
     4921 gctacgtttt cacatgtagc ttctatatct ccaacaatat gtgtagataa aataacgatt
     4981 ctatcatttg caatttcgca tagtaaattt ctaaatctta tacgttcttc tgggtcaaga
     5041 cctgctgtcg gctcatccac tattaaaact ctgggattat gaattaatgc ttgtgctatc
     5101 ccaagccttc tattcatacc tccagataaa gattttactt tcacattttg ataattagta
     5161 aggtttactt tgcttaataa ctttgctata atttttcttc tttttcttag tggtatatcc
     5221 gataaaactg ctaaataatc cattgcttta tatactgtca tgttaggata cattgaaaaa
     5281 tcttgtggca aataaccaac catatttcta atttccttag tattctcaat aggaactcca
     5341 cacatatgta ttgaaccttc tgtttttgat aataaagtgg ctaaaattct cataaatgtg
     5401 gtttttcctg ctccatttct tcctaaaaga ccaaacatac cactgtcgat ttcaagattt
     5461 atattatcaa gagcttgttt tttcccaaat cttttactaa gattggatac tgctattttc
     5521 atttccatat ataaatacac ccccagaaat aattttatag aattttattt ttataaattt
     5581 ttactgtatt ttcataataa attctaaaac ttaagatatt atttataaat ttctaaattt
     5641 tttctaaaga ttttaatttt tctgttttta attaaattaa agtatctttg tttctgaaat
     5701 tttttaagtt tatgaagcta taatttaata tatatttatt ttatttgtga gtctattttt
     5761 atatataatg aaaaatgtga taagtatcca aaagaattac tggatataat aagatagggt
     5821 atttagcctt ttaagataaa taaaaatatc tgcaactata tattgcaaaa atttaaaact
     5881 aatttatata tgctaatata aatatttata aagacataag acaaatttac ctacagattt
     5941 aaatttaact tatatatttt aaaaggctaa tataatatgt attttcttct atacaatcaa
     6001 aaggcttcat atctaagata tgttatgaca ctaatattca caatttttta gtaattatca
     6061 cattataaaa aatattacag ctagtccatc atcagatgct tcttgtataa actttttaag
     6121 ttcaattaga tttgcccata catattcaaa aaaatcatct tcactctcat cattcataac
     6181 aggataaata ttattttcta acatctcatt aatattaaat ctttttctaa atgcttgttc
     6241 ttccaaactg ttcattgctt ttgatagttt ttttacatca tttgctgtaa tcaacatgac
     6301 aggaaattct ccatcaattt ccataagtat gtttccactt agtactaatt tgctaaatat
     6361 attctcatca tctccaccaa aaggacaacc tgtcaaagta aagtgaatgg catgccatgc
     6421 tttatcaata ttgatagtac tattttcgtt ggcatcttca aaaacaaaat cttgtaaatt
     6481 ttcttctgct tgctgtaatt taaaaacatt ctcttcactt attttagtat aacatcctat
     6541 catccccata attacattcc tcctaagtag cgttttttta attgtaactt ataattaaac
     6601 ttagttacaa taaaatatat tgagaaaagt attatttcat cttaaattta aatacctata
     6661 ttatcaacta aaattctgtg tttatagcgt aagtattatt attttttcct aaaaattaaa
     6721 tgaatcagaa gttctatagg caatattgac tataaataag aactattact tttaaaaaaa
     6781 atttaagaaa ttatactgta gaatcatgct ctacttatta gcttcaaata aaaaataaat
     6841 catgttctca aattaaataa taaataacaa taaatttaaa ttttaaacta taagagtttc
     6901 tgaagtgtta ataagcatac caataattat atgtgtaaga atttgattta atagatatga
     6961 ataattttta cattaattat aaatatatta acctattatt ataaattcta taaaaagaaa
     7021 agttatctta aataaaaaat aagtgtatct taaattttaa atgatacact tatttttata
     7081 ttgaaattat attttttaat atctattctt aattaggtat ttttaaatta tctgtttaca
     7141 ttaaatatct cttaattact tatctttcag ctagcttctt ctattaaatg tttctcaaat
     7201 acttattttt caattagcca cttctattaa acatttctta attacttatt tttcaattag
     7261 ccacttctat taaacatttc ttaattactt atttttcaat tagtcacttc cattaaacat
     7321 ttcttaatta tttatttttc agttggcttt ttctattaaa tgtttcttaa ttacttatct
     7381 ttcagttagc tctttctatt aaacatttct caattactta tttttcaatt agctactttc
     7441 attaaatatt tcttaattat ttatctttca gttaactatt tccattagat atttcttaat
     7501 tacctatttt tatcatttat tttatagagt attgtgcact atatatttat acatatcata
     7561 aatactacaa cttgttatct cttattttag ctgttttatc tactcctcta ttttttcaac
     7621 tatctcaaag tcaatttctt taaaatctac attaacactt tcaaccttta tcttaacaag
     7681 gtctcctatc ttatatgact tcttagttct ttctcctaaa acactataag aactctcatc
     7741 ataaatatag taatcatcat tcatatttgc aagtcttatc aatccttcta tagtattatc
     7801 taactcaaca aatattccaa atgaagttac gctagataca acaccctcaa attcttgacc
     7861 aactttatcc ttcatataaa gagccttata gaaatcatgt acatctcttt cagctaactc
     7921 tgcctttctt tctttctcgg atgattgaac agatgcataa tccactatag tagtaagctg
     7981 ttcttgtctt tttccactta ttttattatt taaagattct tttattattc tatgaatttg
     8041 aaggtcagga tatcttctta ttggtgaagt aaagtgacag tagaatttag ctgctaatcc
     8101 aaaatgtcca ctacattctg gtgagtactt agcttgtttt aaagaacgaa gcattatagt
     8161 actgatagct ccttcttctt ttttgccctt tattttctct attatacctt gtaatgcttt
     8221 tggatgtact tcctctttat caccttttat tatatatcca aatgtagata taaacttact
     8281 caattcttcc attttttcca aagatggtgt ctcatgtatt ctatacacaa acggtattcc
     8341 catccagtaa aaatgttcgg caattgtctc attacttata agcataaatt cttctattat
     8401 cttattagat attcttcttt catatggctt tatatctaca acttcgcctt ttccatttag
     8461 aattatcttt gcctctggga aattgaagtc tatagctcct cttttttccc ttcttgacat
     8521 aagaatctta gctaaaattt cagcattttt aaaatcttca acaacatgtt caaaagtctt
     8581 tttaagtttt tcatcatcct tttctaatat atcagatact tctgtataag tcattctagc
     8641 ttttgaattt attacagatt cacatatttc atgtttaacc acatttcctt tatggtctat
     8701 ttccataaat atagaaagag ttaacttatc ttcaaatgga tttaagctac atactccatt
     8761 tgaaagagtt tttggcaaca ttggaattac tttatctact aaataaactg atgtagctct
     8821 ttttaaggct tccttatcaa gtttattttt ctctcttaca taatgtgtaa catcagctat
     8881 gtgaactcct agtttgaagt ttccattagg taatacttct attgatatgg catcatctaa
     8941 gtcttttgcg tcatctccat ctatagtaaa tatgtttaaa tctcttaaat ctcttcttct
     9001 ttttatctct tcttgaggaa tctcaacagc tacagcttct gcttctgctt cttgcaatac
     9061 tttctttgga aattcttctg gaagaccatg ttctcttatt atagaatcta tttctacgcc
     9121 tctttcacct ttttgaccta gtatctctat aattttgcct tctggttttc tatcctcttg
     9181 tggccatact gtaatttcac atactacctt atcattatct actgctccac taaaatgttt
     9241 tttaggtata tatatatctt tagtaaattt cttgttgtct ggtgttacaa atccaaaagt
     9301 tttacttgat tggaaagtac ctactattct agttatttct ctctttatta cttttactat
     9361 tcttccttct gctctctttt cttcagttgc aggtactact atttctgcca taactctatc
     9421 gttatgcata gcaccattta tattgtcact tgagataaat aaatcctgtg tatattcaac
     9481 atcagattct acaaatccaa aacccttttt gtgtgataca aattttccaa caaagtatcc
     9541 catttgattg ggagatacta tttttccttt tttagtaaag cagatataac catcttcttc
     9601 taattcattt aaaaaattat aaaacattgg catttctgat gaatgtatat caaatatttc
     9661 tgctaattct tcttttttta gaggattata tgcactttca tttattaatc ctagcaaact
     9721 ttctttaagt cctggtatca tttttccctc ctgttttact tttcattata ttattattta
     9781 tattgtcttt tatatttctt cagataaaac attttttact tatcacataa ttttctatat
     9841 tttcttatta tcattacaag ttaaaattac ttatttatat ttttgattta atgtaagctt
     9901 tgtcatacta acttcaaaca aattatgatg ttttataaat tatttgtaaa tatcattata
     9961 attacttaag ttattcttta tcataattgc ttaaattact ctttatctca taattataca
    10021 ccatcaaata ggattggtaa aatattcatc tcatataagt attactatat aataatttat
    10081 tctattagta tactcaaatc atgtaaaatt tatataactc aattaatttt ttaaatacaa
    10141 ctttataata taaaacttat aataaaagta aatttatatg ttaaatgagg ttgatttttt
    10201 attatttttt atttatgcta gtactaaaga cttgcaaacg ttttttgaca agtctttatt
    10261 ttgtctaaat taaacaaact tttttacaaa taaatacata aaatttaaac taatctattt
    10321 attggaggag ataaaattgg aagaagtaat tgcaaaaatt attactatag aaaatggatt
    10381 caaagaaatt gaaaacattg ctaaaaaaat tgtaaaaaat aatgactcaa aaaagtgtta
    10441 ttatctatca atctacttat ataggtcaga atattatcaa gtaagagaat tggctgtgtt
    10501 tatacttggt tttatatcag taactatttc tgaagctttg ttatttttaa aagacaatgt
    10561 gagtaaagat gaaaactgga gagtacaaga aatactagct aaatcatttg attattattg
    10621 cagtgaagta ggatatgaaa aggcacttcc tgttataaaa gaatggctta attctgatag
    10681 tccaaacata aaaagggctg tgacagaagg tcttagaatt tggactagta gagactattt
    10741 taaatctaat cctgacgttg ctatatcact actttctagt ttaaaagaag atgatagcga
    10801 atacttgaga aagtctgtag gtaatgctct tagagatata agtaaaaaat atccagattt
    10861 agtaaaaaaa gaattagatt catgggatat atcaaataaa aaagttgagt ttgtatataa
    10921 gcttgcttca aaatgtatct tggcaaagta aaatggaggt gaacttattt gaaacttcgt
    10981 gatgagtata cttgcccatt agaactaaca catgatatga taaaaggcaa atggaaatct
    11041 attatattat ggagattacg cataggacca acctccttat caaaacttga aaaggaaatc
    11101 aatggtatta atcaaaagat gttacttgaa caacttaaag aattaattga atttggtctt
    11161 gtagataaaa agacatataa aggttaccca cttaaagttg aatactcact tacacctatt
    11221 cgagggaaac aaatattgga tgctttggct ataatgcaag atataggaat tagctttatg
    11281 ttggataatg gtatggaaga tattcttaag gaaaaaggtg ttttaaagta aatagatacc
    11341 cacaaaaaag taagtaattt accattattt tcaactggta tataattaaa ttatagatat
    11401 attctattaa tttattataa taggaggtaa attattatga aagtaactag tacaggtata
    11461 gtaaatggtg ttatagaaga taaatatggt aaaagaggaa ctcagttcaa tgaaggtggt
    11521 atgcctacat attcactacc tctaaagttt gaagatgctc caaagaatac agtatccttt
    11581 gctgtatttt tagaagataa agactctgtt cctgtatgtg ggtttgcatg gatacattgg
    11641 ttagctgtaa atataacaaa agatgagtta aatgaaaatg aaagtgtaac agctactgat
    11701 tttgtacaag ggactactag ttggcatggc aaactaggag gtcttgacag attagaggcc
    11761 agtgtatatg gtggaatggc tcctccagac agacctcatg tctatgaaat acatgtattt
    11821 gcacttgata ctatccttga ccttgaaaaa ggattctata tgaatgaatt tttcaaagct
    11881 attgaagggc atattttaga tacatttaca ctaaaaggaa gttattctaa ttaattaggt
    11941 tgactatagc taatcattaa ttaaatgcta catttaattg atgattagct taattgttat
    12001 tagaatattt tctgcacttt atcttaatat atattttagt tgactggtat tttaatttct
    12061 attagattat tatcaattta tataaattga ttttagctta aaacttactt atctatttca
    12121 gtttctatta gaattattat tagactcatt aaaataaaag cattaatata actaataata
    12181 tatgttaaat tcattaactc tacataaagt tttataatct aaatgaaata caataatctg
    12241 cataaaattc aatagcttat ataaaattta ataatttata taaacattat caatctatat
    12301 aaaatttagt aatttatata aatattatca ac
//
LOCUS       DACTZW010000108        12296 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.109, whole genome shotgun sequence.
ACCESSION   DACTZW010000108 DACTZW010000000
VERSION     DACTZW010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12296
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.109"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(148..927)
                     /locus_tag="JAM15_16775"
     CDS             complement(148..927)
                     /locus_tag="JAM15_16775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur protein"
                     /protein_id="HAT6799906.1"
                     /translation="MNSKIYYFSGTGNSLVVSKILKETLNGSKEVIPLAIHRKENNID
                     INEDILVIVFPVYFADVPDIVKSFVEKLNFNINTHIYAIATCNGVAGHSLFTIDKLLK
                     KRGKKLSAGFLINMPGNALITPPDVEEERLKNQTNRVAEIAKCINNLEIGNIEGKNNL
                     KSHIDSVVLRLVGKNMQIATTKFFTENKCNGCGTCKRVCPVENISIVDKKPKWGNECE
                     RCLACFHWCPKEAINVKKSFLTNRKKYHHPDITVKDIFLDK"
     gene            complement(995..1456)
                     /locus_tag="JAM15_16780"
     CDS             complement(995..1456)
                     /locus_tag="JAM15_16780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAT6799907.1"
                     /translation="MGGARDYLNGGKMKDFEKLYEATTKLVSTSLKVKDDLKKMFKQN
                     GYDITTDHYALLRFLWEQDGISQIDLCEKSCKDKSNTTRILDVMKNKGLIVRKVDVKD
                     RRKFQIFLTDLGRELEEPLNEIASIYATETFKSISDEELPLFTNILDRIGK"
     gene            complement(1432..2109)
                     /locus_tag="JAM15_16785"
     CDS             complement(1432..2109)
                     /locus_tag="JAM15_16785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HAT6799908.1"
                     /translation="MIITVINGSPRKNGATSKVLTYLYKDIERLIPDVKINYFDLSEV
                     NPSYCIGCLNCYKMGKCINQNDKVEYIHDIITKSDGVIFGSPTYGSSVTGLFKVFTDR
                     AHMMLERLLYRKPCIAVTTYENARGSKAISFIKSMVLDSGGYVCGSLSIKTGFNQNPI
                     TEKVESKIRKVSKKFIYCIEERKNPPVLSQIYNFIAINAVLKPMAFKDIEQYKGIIDR
                     WEEQGII"
     gene            2342..2728
                     /locus_tag="JAM15_16790"
     CDS             2342..2728
                     /locus_tag="JAM15_16790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HAT6799909.1"
                     /translation="MKKLPHISEAEYQVMKIIWRYAPISTTEVIEKLVETSTWSPKTI
                     QTMLLRLVKKGALTYEKNSRVFVYTPLVKEEEYVAKESSSFLNRFYNGTLNSMVLNFL
                     ENDKLSEDDIEELREILNKRTTKGDK"
     gene            2731..4530
                     /gene="blaR1"
                     /locus_tag="JAM15_16795"
     CDS             2731..4530
                     /gene="blaR1"
                     /locus_tag="JAM15_16795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaR1 family beta-lactam sensor/signal
                     transducer"
                     /protein_id="HAT6799910.1"
                     /translation="MYAPFFIRFLLSTLTLSILIVVILLAKKVFKNHISAKYQYNIGF
                     ILLIMLIIPFVPLKYINLGNVFNYLYTFNQLGSSTNRTSMIKNSPNSIINNSNALNDF
                     SVSLNQVNFDSLNILLLISWIIGILIMIAITIHCNIKIKNIKKSIQILRDEEIVFIFE
                     KCKKDIGINKDFILCKSPIINTPITFGYFKPHIILPDKSISKLSLKDIKYILLHELQH
                     FKNKDILINYIMCFLQILYWFNPLVWYAFKEMRIDREIACDISVLKKLDKDSHIEYGQ
                     TLINFVDNISRPSNLTLTSDIGGSKKQIKKRLLKIMDFHNESNTLKFKSILIFTLIAL
                     IVFGNIPKLSIMADINEKYRPTNEQTVYEDLSQYFKGFDGSFVMYDLKSKQYHIYNKE
                     KSKTRISPNSTYKIYSALLGLENGIITRNNSHIPWDGKHHSNSSWNEDQDLFSAMENS
                     VNWYFQTLDKKTGLKNIQTYLKQIGYGNYDVSGGISNFWLESSLKISPIEQVELLESF
                     YTNKFKFEDKNIETVKDSLLISKKDGVSLFGKTGTANINGKDVNGWFIGYVEKNENTY
                     FFATNIQSKNYSNGSSASKITLSILNDKKIYNP"
     gene            complement(4885..6759)
                     /locus_tag="JAM15_16800"
     CDS             complement(4885..6759)
                     /locus_tag="JAM15_16800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAT6799911.1"
                     /translation="MNKYNKIANELIEIIGENNIISITHCATRLRVMVKDREIINDKK
                     VEKVNEVKGVFFTSGQYQIILGTGIVNKVYAEVEKMGLKTLSKKEQDELVKNNETGFK
                     KVMRTLADIFVPIIPVIAATGLFLGLKGCLFNDNVLGLFGMSSANIPLYIQTLVSVLT
                     ETAFAFLPAIIVWSAFKVFGGTPVIGLVIGLMLVSPILPNAYSVADPSNEVEAIMAFG
                     FIPIVGCQGSVLTAIVTAFIGANLEKWFRKHMPNVLDLIFTPFFVMLITMLVILLGVG
                     PIMHTIELKMVDIISLLIGLPLGIGGFIIGFTYPLAVITGLHHTYVMIETSLLANTGF
                     NALITLCAMYGFANIGTCLAFMKKSKNNQVKQTAVGAMLSQLFGISEPVLFGIQLRYN
                     LKPLIIMCASSGLGAAILSILHIQSNSYGLAVLPSYLMYIYDGYNLITYLLVSIFVVA
                     FCFIVTCLFGVPKEAINEDEDEELVFNENNENFVSPAKGKIVALENVPDETFSKKMLG
                     DGFAIDIIDGKIVSPISGKLETVFSSGHAFGIKGTNGEVLIHVGIDTVTLNGDGFDIA
                     VKQGDMVKQGDVLVNVDLKRIHELGKSTLTMVLFPDGKKVNILDINKDVKIGQRICVE
                     "
     gene            complement(6764..8428)
                     /locus_tag="JAM15_16805"
     CDS             complement(6764..8428)
                     /locus_tag="JAM15_16805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HAT6799912.1"
                     /translation="MEKKWWQKEIVYQIYPRSFQDSNNDGIGDLQGIISRLDYLKDLG
                     ITSLWLCPIFKSPMDDNGYDISDYLDIASEFGSMEDLKELIKKSKDRGIKIILDLVLN
                     HTSDEHPWFQEALKNPESPYHDYYIFKKGNDLPNNWRSVFGGSVWEKVENRDEYYFHS
                     FGKKQPDLNWENPILRSELYQMINTWSQMGVAGFRVDAITFIKKNLSFQSLESDGVDG
                     LVKCTKTVRNQPGIEKMLYELKENTFKKYDCMTVAEAAGISYDQLGDFIGEDGFFSMV
                     FDFKHADLDVASGSEWFKRISWTIPDLRKCILDSQMYVQEHGWAANFIENHDQPRATT
                     KYLLQYERNDDAVKMLGAMYFFLRGTPFIYQGQELGMTNFKRDTINDFNDLSSIDQYY
                     RSIDEGYSEEEALEFVNLRSRDNARTPFPWADKENAGFSDATPWLKVIENYKDINAQS
                     QINNSESILEFYKKMIKLRQDSEYSDCLIYGSIEPIDIESDNVIAYRRQLDLVVIDCY
                     YNFSDKPVEIKTEEKYDIVFQNLDDINLLNKTVSLKPFQAVLLKVR"
     gene            complement(8442..9257)
                     /locus_tag="JAM15_16810"
     CDS             complement(8442..9257)
                     /locus_tag="JAM15_16810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAT6799913.1"
                     /translation="MYKLLILDIDGTLRDEVYGIPESAKHAIRLCQKNHCSVVICTGR
                     SIGTIQDDVLSLGVDGYIAGGGNYIQYHGELLYNQSFNQRLIKEVVCLLKKREVAFSI
                     ESQEKVFMNQKAKEIFETMNQLKGTNSCINKQHIQEKITYENNIEEYKSQDVHKICLW
                     SNEKVFDEVKDILQDKMELAQRDISSQYYEIIQKDFHKGKAIKRLQERLGVTQKETIC
                     FGDGQNDIVMFQASDVTIAMKNSHQQLKDIATSICEDIFDNGIYKELKRRNII"
     gene            complement(9362..10126)
                     /locus_tag="JAM15_16815"
     CDS             complement(9362..10126)
                     /locus_tag="JAM15_16815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAT6799914.1"
                     /translation="MKIEGLFNKYYNSFTANDKYICECILNHKEDCIKLSIDEFADKY
                     HISTSALSRFAQKLQLPGYSELRVIIRLNETEVEYKNQSKHQLMDCYNKVIDDIEKKD
                     CSIMFERMKKANRIIVFGEGYSQERVVKEMKRIFLPTGKIIYDVYGYDMIQALNHFIK
                     TDDMIFFISLNGDASTIIDFAKEMRMKGTYMVSITKMISNPLARLCDENLYIQSISIS
                     VDKQLDYDVTTPYFILIELLYIKYKMYLESEHIPRK"
     gene            complement(10123..10872)
                     /locus_tag="JAM15_16820"
     CDS             complement(10123..10872)
                     /locus_tag="JAM15_16820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAT6799915.1"
                     /translation="MRLESLVNQSYNSLNENDKIIIKQILICQREYRNFSCEKIANEC
                     NVSRATLLRLCRKIGLDSFSDLKYLLKNNQLEFVNNDNNFHDVCENYRLLMNELQKIS
                     FQDICKIIYDAETIYIYGTGNEQKSLAQEIKRIFLSVGKCVIDLFDIGEIEFMRESFQ
                     KSDLFIIISLSGETKAGIEIAKFINNHIHTISLTRLDNNTIATLCEYNLYVETQKLDT
                     LQAISYEVVGAFYALLDLLHMNYIEYRRRKE"
     gene            complement(11376..11981)
                     /locus_tag="JAM15_16825"
     CDS             complement(11376..11981)
                     /locus_tag="JAM15_16825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAT6799916.1"
                     /translation="MKIKENVLMLDSTRGSNCFIVFDKEIILIDTGLPFMGKNIIKEL
                     KTLGIKLTDIKHILLTHHDVDHISNIKLLKEKTGAKVWAHVEDIPFIIGEKDRPGFKK
                     FIGKAISRRLIKDVEPYGENMKIGNIKIIHTPGHTPGHVCMIFEDVLFAGDLVKNKNG
                     NIVPYPNPWNWDYKKMVKSIRELDNLKYEWICMSHGTPCVK"
     gene            12160..12258
                     /locus_tag="JAM15_16830"
     CDS             12160..12258
                     /locus_tag="JAM15_16830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HAT6799917.1"
                     /translation="MSELSKRDKEKIQRENEIIDKAEKLFCLNGFD"
BASE COUNT         4329 a         2052 c         1315 g         4600 t
ORIGIN      
        1 aacataattt attatttata ttgttctttt taatctctat tccatttagt ctaggtaaca
       61 ttactcttta caagattact ttatatttct tttatatctc taacgttttt atttaataaa
      121 acaattatta atacaagtca aatatatcta tttatctaaa aatatatctt ttacagtaat
      181 atctggatgg tgatacttct tcctattcgt taaaaaagat ttttttacat taatagcctc
      241 ttttggacac cagtgaaaac aagctaggca tctttcacac tcattacccc actttggctt
      301 tttatcaact atacttatat tctctacagg acaaaccctt ttacatgtcc cacatccatt
      361 acatttattt tctgtaaaaa atttagtagt tgcaatttgc atattcttac ctactaaacg
      421 aagtacaaca ctatctatat gtgactttaa attgtttttt ccttctatat ttccaatctc
      481 caagttattg atacattttg caatctcagc taccctatta gtctgatttt tcaatctttc
      541 ttcttcaaca tctggaggtg ttatcaaagc atttccaggc atattgatta aaaaaccagc
      601 agataatttt ttcccccttt ttttaagtaa cttatctata gtaaataaac tatgtccagc
      661 taccccatta caagtggcaa tggcatatat atgagtatta atattaaaat ttaatttctc
      721 tacaaaagac tttactatat caggaacgtc agcaaaataa acaggaaaaa caattaccaa
      781 tatatcttca tttatgtcta tattattttc ttttctatgt atagctaaag gtataacttc
      841 tttacttcca tttaacgttt cttttaaaat ctttgaaact actagcgaat ttcctgttcc
      901 agaaaaataa taaatcttac tattcattct tatccctctt tctatatttc tacatcatca
      961 atagttaaaa agtctcttaa aataggattt atatttactt tccaattcta tccaaaatat
     1021 tagtaaacaa aggcaattct tcatcagaga tagatttaaa tgtctctgtt gcatatatac
     1081 ttgcaatttc atttaatggt tcttctaatt ctctacctaa atctgttagg aatatttgaa
     1141 acttacgtct atctttaaca tctactttac ggacaattaa tcccttattt ttcataacat
     1201 ctaagattct tgtcgtatta gatttatcct tacatgattt ttcacataaa tctatctgag
     1261 aaattccatc ttgctcccat agaaacctta ataacgcata atggtcagtt gttatatcat
     1321 atccattttg tttaaacatc ttttttaaat catcttttac ttttaacgaa gtacttacta
     1381 acttagttgt agcttcatat agtttctcaa aatctttcat tttacctcca tttaaataat
     1441 cccttgctcc tcccatctat caattattcc cttatattgc tcaatatctt taaaagccat
     1501 tggctttaaa acagcattta tagcaataaa attatagatt tgagaaagta caggtggatt
     1561 tttcctttcc tctatgcaat aaataaattt tttagatacc tttcgtatct ttgattctac
     1621 tttttcagtt ataggatttt gattaaatcc agtttttata gataaactac cacaaacata
     1681 acctcccgaa tctaagacca tggattttat aaaagaaatt gcttttgaac cacgtgcatt
     1741 ttcatatgta gtaactgcta tacatggctt acgatacaat aatctttcaa gcatcatatg
     1801 tgctctatct gtaaacacct tgaaaagtcc agttacacta cttccatagg ttgggctacc
     1861 aaatataaca ccatcactct tagtaattat atcatgaata tactctactt tatcattttg
     1921 attgatacac ttgcccattt tataacaatt taaacaacca atacaatatg atggattgac
     1981 ctcacttaaa tcaaaataat taatttttac atctggtatt aatctttcta tatctttata
     2041 caagtaagtc aaaacttttg atgtagctcc attttttcta gggcttccat ttataactgt
     2101 aattatcatt tctatatctc ctttttagtt gttatatcaa caataagtat atcaactata
     2161 tttttaactg tcaatatgaa ccatttattt aaagctatac ttacacagct taaataaaag
     2221 ttttatttaa ctacatgtgc ttatttaatc aactataaat gaattatttt taataattga
     2281 caaactaaat taatgataat atactttatg tattacaaat gtaagtagaa ggaggtatag
     2341 tatgaaaaag ctaccacata tttcagaagc agaatatcaa gttatgaaaa ttatttggag
     2401 atatgctcct atcagcacta ctgaagtaat tgaaaagttg gtagaaacaa gtacatggag
     2461 tcctaaaaca attcaaacaa tgttattgag attagttaaa aaaggagctt taacatatga
     2521 aaaaaatagc agagtattcg tttatactcc acttgttaaa gaagaagaat acgtagctaa
     2581 agaaagtagt tcttttttaa atcgttttta taatggtact cttaattcta tggtactaaa
     2641 ctttttagaa aatgataaac tatctgaaga tgatattgag gaactgagag aaatcttaaa
     2701 taaaaggacg actaaggggg ataaataaat atgtatgccc cattctttat acgattttta
     2761 ctcagtacat taaccttatc aatattaatt gttgtaattt tacttgccaa aaaagtattt
     2821 aaaaaccata tttctgcaaa gtaccaatac aatattggat ttatattgct tataatgtta
     2881 ataattccat ttgtccctct taaatatatt aatcttggaa atgtatttaa ctatttatat
     2941 acttttaatc aacttggaag cagtactaat aggacttcta tgataaaaaa tagtccaaat
     3001 tctataatta ataactcaaa tgcattaaac gatttttcag tatccctaaa ccaagttaat
     3061 tttgatagtt taaatatttt attactaata tcatggataa ttggaatttt aatcatgata
     3121 gctattacta ttcattgcaa cattaaaata aaaaatataa aaaaatcaat acaaatttta
     3181 agagatgagg agatagtatt tatatttgaa aagtgtaaaa aagatattgg tataaataag
     3241 gattttatac tatgcaaatc acctattata aatacaccta ttacatttgg atactttaaa
     3301 ccacacatta tattaccaga taagtctata tctaaattat ctttaaaaga tataaaatat
     3361 atcttacttc atgaattaca acattttaaa aataaagata tactgataaa ttatataatg
     3421 tgctttcttc aaatattata ttggtttaat cctcttgtat ggtatgcatt taaggaaatg
     3481 cgtatagacc gtgaaattgc atgtgatatt tcagttttaa aaaagcttga taaagatagt
     3541 catatagaat atggacaaac tctaataaac tttgtggata atatttcaag accatcaaat
     3601 cttacactta catcagatat tggtgggtca aaaaaacaaa taaaaaagcg actattgaag
     3661 ataatggatt ttcataatga atcaaatacg ttaaaattca aaagcatttt aatttttaca
     3721 ttgatagctt taattgtatt tggaaatatt cccaaactat ctattatggc agatatcaac
     3781 gaaaaatata gacctacaaa tgaacaaact gtgtacgagg acttaagtca gtattttaaa
     3841 ggttttgatg gaagttttgt tatgtatgat ttaaaatcca agcaatatca tatttacaat
     3901 aaagaaaaaa gtaaaacaag aatttctcca aattctactt ataagattta tagtgcctta
     3961 ttgggattgg aaaatgggat aataacaaga aataattcac atatcccttg ggatggaaag
     4021 catcattcta atagttcttg gaatgaagac caagacttat tttctgctat ggaaaactcc
     4081 gtaaactggt actttcagac tctagataaa aaaacagggc taaaaaacat acaaacttat
     4141 cttaagcaaa ttggatatgg caactatgat gtttcaggtg gtatctcaaa cttttggcta
     4201 gaatcttcat taaaaatatc acctattgaa caggtagaat tacttgaaag tttttataca
     4261 aataagttta aatttgaaga taaaaatata gaaacagtaa aagattcatt gttaatatca
     4321 aaaaaggatg gggtatcact ttttggtaaa acaggcactg ctaatataaa tggaaaagat
     4381 gtaaatggtt ggtttatagg ttatgtggaa aaaaatgaaa atacttattt ctttgctaca
     4441 aatattcaaa gcaaaaatta ttctaatggt agttcagcat ctaagataac attatctata
     4501 ttaaatgaca aaaaaatcta taatccttaa tatatttact gtacattcta aaaaattcac
     4561 ataattttca tattaattat cgattaaatt catatacaag gcttattata taaacataga
     4621 agatagtaaa actagcttaa aaacataata taatacccta tacaaatagt ggcaactctc
     4681 cctcacatcc tcaattgttg ccactattta attttttgta tgaagttaaa tatattttca
     4741 tcatttcaac aatttgggtg cagtacaatc tctattttga aacaacctct ttaattgttt
     4801 tagagtttat gaattatttc tcatacttta aaaagattga attactcttg ataatcttct
     4861 tttgtagtca ttacatatca cctactactc aacacatatt ctttgaccta tttttacatc
     4921 cttgtttata tccaaaatat ttaccttctt accatctgga aacaatacca ttgtcaaagt
     4981 agactttcct aattcatgta ttctctttaa atcaacatta acaagaacat ctccctgttt
     5041 aaccatatct ccttgtttaa cagcaatatc aaagccatct ccatttaatg taactgtatc
     5101 aattccaaca tgaattaata cttctccatt agttccttta atcccaaatg catgtccact
     5161 tgaaaatact gtttctaatt tacctgaaat aggagaaaca atttttccat ctataatatc
     5221 aatagcaaaa ccatcaccta acattttttt agaaaatgtt tcatctggta cattttctaa
     5281 tgcaacaatt ttccccttag ctggagacac aaagttttca ttattttcat taaacactaa
     5341 ttcttcgtct tcatcttcat ttatagcttc tttaggcact ccaaataaac atgttacaat
     5401 aaagcagaat gcaaccacaa atattgatac taataagtat gtgattaaat tatatccatc
     5461 atagatatac attaaataag aaggtaaaac tgctaatcca tatgaattag attgaatatg
     5521 taaaattgat aatattgctg ctcctaaacc tgaagatgca cacataataa tcaaaggctt
     5581 taaattatat cgaagctgaa tcccaaataa aacaggctca cttataccaa aaagttgaga
     5641 tagcattgct ccaactgcag tttgtttaac ttgattattt ttagattttt tcataaatgc
     5701 tagacatgtt ccaatattcg caaatccata cattgcacaa agagtaataa gtgcattaaa
     5761 tcctgtattt gctaatagtg atgtttcaat cattacataa gtatgatgta agccagtaat
     5821 aacagctaat ggatatgtaa atccaataat aaatcctcca attcctaaag gtaaaccaat
     5881 caataagctg atgatatcaa ccatttttaa ttctattgta tgcattatag gccctacacc
     5941 taacaaaata actaacattg ttattagcat aacaaagaat ggtgtgaaaa taaggtctaa
     6001 tacattaggc atatgtttac ggaaccattt ttcaagatta gctccaataa atgctgtaac
     6061 aatagctgtt aaaacacttc cttgacagcc tacaatagga ataaatccaa atgccataat
     6121 tgcttcaact tcatttgatg ggtcagcaac agaatatgca ttaggaagta ttggagaaac
     6181 taacataagt ccaataacaa gtccaataac aggtgttcct ccaaatacct taaatgctga
     6241 ccatacaata attgctggta aaaaagcaaa tgctgtttct gtaagaaccg aaacaagtgt
     6301 ctgaatatac aatggaatat ttgcagaaga cattccaaat aatccaagta cattatcatt
     6361 aaacaaacaa ccctttaatc ccaagaataa tcctgttgcc gcaataactg gaataatagg
     6421 aacaaatata tctgctagag ttctcataac tttcttaaat ccagtttcat tatttttaac
     6481 taattcatct tgttcttttt ttgataaagt tttcaatccc attttttcaa cttctgcata
     6541 aactttattg actattcccg ttcctagaat aatttgatac tgtccagaag taaagaaaac
     6601 acctttaacc tcattaacct tttccacttt cttatcatta ataatttctc tatctttaac
     6661 catcaccctt aatcttgtgg cacaatgtgt aatagaaata atattatttt caccaataat
     6721 ttcaataagc tcatttgcta ttttattata tttattcatt tttctacctc actttcaata
     6781 atactgcttg aaatggtttc aaactcactg ttttatttag tagatttata tcatctaaat
     6841 tttggaatac aatatcatat ttttcttctg tttttatttc tacaggttta tcagaaaaat
     6901 tataataaca atcaataact accaaatcta attgccttct atacgcaata acattgtcac
     6961 tttctatatc aataggttct attgaaccat aaatcaaaca atcagaatac tcactatctt
     7021 gtctcaactt tatcatcttt ttataaaatt ctaaaatact ttctgaattg ttaatctgac
     7081 tctgtgcatt aatatcttta taattttcaa taacctttaa ccatggtgtt gcatctgaaa
     7141 aacctgcatt ttctttatct gcccatggaa atggcgttct tgcattatct cggcttctta
     7201 aattcacaaa ttctaacgct tcttcttctg agtaaccttc atctattgaa cgatagtatt
     7261 ggtcaatgct agataaatca ttaaaatcat ttatggtatc tcttttaaaa tttgtcattc
     7321 ctaattcctg tccctgataa ataaatggtg ttcctcttaa aaagaaatac attgctccca
     7381 acatttttac tgcatcatca ttcctttcgt attgcaaaag atactttgtt gtagctcttg
     7441 gttggtcatg attttcaata aaattagctg cccatccatg ttcctgaaca tacatttggc
     7501 tatctaaaat gcattttctt aaatctggaa ttgtccatga aattctttta aaccactcac
     7561 taccagaagc aacatctaag tcagcatgtt taaagtcaaa gaccattgaa aagaaaccat
     7621 cttctccaat aaaatcacct agctggtcat agctaatacc tgctgcttca gcaacagtca
     7681 tacaatcata ttttttaaac gtattttctt ttaattcata aagcattttt tctattccag
     7741 gctgatttct aactgttttt gtacatttaa caagaccatc aacaccatca ctttctaaac
     7801 tttgaaaact taaattcttt ttgatgaatg taatagcatc aactctaaat cctgccactc
     7861 ccatttgaga ccaggtatta atcatttggt aaagttcact tcttaatatt ggattttccc
     7921 aattaaggtc aggttgtttt ttaccaaaag aatgaaaata atattcgtct ctattctcta
     7981 ccttttccca aacacttcca ccaaaaacag acctccagtt atttggtaaa tcgtttcctt
     8041 ttttaaaaat ataataatca tgataaggac tttctggatt ttttaatgct tcttgaaacc
     8101 aaggatgttc atcacttgta tgattaagaa ctaaatctaa tataatcttg attcctctat
     8161 ctttactttt tttaattaac tcttttaaat cttccatact tccaaattca cttgcaatat
     8221 ccaaataatc actaatatca tacccattat cgtccatagg tgatttaaaa attggacata
     8281 accacaatga tgtaatacct aaatctttta aataatctaa acgagaaata attccctgta
     8341 aatctccaat tccatcatta ttactatctt gaaagcttct tggataaatt tgataaacga
     8401 tttctttttg ccaccatttc ttttccataa attactcctt tttatatgat atttcttctt
     8461 tttaattctt tataaattcc attatcgaat atgtcctcac atatagatgt cgctatatct
     8521 ttaagttgtt gatgactatt tttcattgca attgtaacgt ctgatgcttg aaacatgaca
     8581 atatcatttt gaccatcacc aaaacatatg gtttcttttt gagttacccc taatctttct
     8641 tgtaatctct taattgcttt gcccttatga aaatcttttt gaataatttc ataatactga
     8701 ctagaaatat ctctctgtgc taattccatt ttatcttgta gtatatcttt cacttcgtca
     8761 aatacctttt catttgacca taaacaaatt ttatgtacat cttgtgactt atactcttca
     8821 atgttatttt catatgttat tttttcttgg atatgttgtt tatttataca agaattagtt
     8881 cctttcaact gattcattgt ttcaaatatt tctttggctt tttgattcat gaaaactttt
     8941 tcctgactct caatcgaaaa agcaacttct ctctttttta acaaacaaac aacttccttt
     9001 atcaatcttt gattaaaaga ttgattataa agtaattcac catgatattg aatgtaatta
     9061 cctcctcctg caatatatcc atcaacccct aatgataaaa catcatcttg tattgtacct
     9121 atacttcttc cagtacaaat aacaacactg caatgattct tttgacataa acgtatagcg
     9181 tgctttgcag attctgggat tccatatacc tcatctctaa gcgtaccatc tatatcaagt
     9241 attaataatt tgtacaattt catcttcctt tcttactatc aaaatcataa tagcattcaa
     9301 aaaaaaagat atcaatattt tgatatcttt taaaaaatat gttcattttt agcacaaatt
     9361 tttactttcg gggaatatgt tcactttcta aatacatctt gtatttaata taaagcagtt
     9421 caattaaaat aaaataaggt gttgttacat cgtagtccag ttgtttatct acagaaatag
     9481 atatagattg aatatacagg ttttcatcac ataatcttgc taaaggatta cttatcattt
     9541 ttgtaataga aaccatataa gttcctttca ttctcatttc tttagcaaaa tcaataattg
     9601 tagatgcatc tccattcaat gagataaaga aaatcatatc atctgttttt ataaaatgat
     9661 taagcgcctg aatcatatca taaccataaa catcatatat aattttccct gttggtaaga
     9721 aaatcctttt catctcttta acaactcttt cctgagaata accttctcca aagacgatta
     9781 tacgatttgc ctttttcatt ctttcaaaca taatcgaaca atccttcttc tctatatcat
     9841 ctatcacctt attataacaa tccattaatt ggtgtttact ttgattttta tattctactt
     9901 ctgtttcatt taagcgtata ataactctta attcactata tccaggtaat tgtagttttt
     9961 gagcaaaacg agaaagtgca cttgtagata tatggtattt gtctgcaaat tcatctatag
    10021 aaagtttaat acaatcttct ttatgattaa gaatacactc acagatatac ttatcatttg
    10081 ctgtaaatga attataatat ttattgaaaa gtccttcaat tttcattctt ttctccttct
    10141 atactctatg taattcatat gaagcaaatc taatagagca taaaatgctc ctacgacttc
    10201 ataagatata gcttgtaatg tatcaagttt ttgcgtttca acatacagat tatactcaca
    10261 aagtgttgca attgtattat tatcaagcct agttaaagaa atcgtatgta tatgattgtt
    10321 gataaatttt gcaatttcaa ttcctgcttt tgtttctcca gacaaagaaa tgataataaa
    10381 taaatcactt ttttgaaatg attctctcat aaattcaatt tcacctatat caaataaatc
    10441 aataacacac ttacctactg aaagaaatat tctctttatt tcttgagcta aacttttctg
    10501 ttcattacct gtcccataaa tataaattgt ttctgcatca tatattattt tacaaatatc
    10561 ttgaaatgat attttttgta attcattcat taatagtcga taattctcgc aaacatcatg
    10621 aaaattatta tcattattaa caaattctag ttgattattt ttaagtaaat actttaaatc
    10681 agagaatgaa tctaatccaa tttttctaca aagccttaat aaagtagctc tagaaacatt
    10741 acattcattt gcaatttttt cacacgaaaa attacggtat tctctttgac aaatcaatat
    10801 ttgtttaata ataattttat cattttcatt taaactatta taactttggt taactaacga
    10861 ttctaatctc attttttcca ctccctaaat attattttaa tatacattag ttgctttttc
    10921 tagtgaagag tcttaaataa taaggataaa ataatcattt gattttattt ttattaaaat
    10981 aaaaataacc tgctaaaaac aggcaccaaa aagtacttat cctttcgaac atgtacttta
    11041 gatattgctt tcttcggaag cttcatctct tcatactcta aaatagagtt ttttctaact
    11101 caaaagtatt ttccatggta gaaattactt taattcatct gccatttatt ttttatctta
    11161 tttaataatt actattactt gaatatttac ttctttaagt aaatttcata gttaacaaag
    11221 ctaaaactat tattatagat gttaaaatac aaaattgtaa gtattgttat aaatatgctt
    11281 acaactacaa atatacatga tatattaaaa agaagctgta aattattatc atacatacaa
    11341 gcaactatgc ctctattaat ccatgttaat ttttattatt taacacaagg agttccatga
    11401 gacatacata tccattcata ttttaaatta tccaattctc ttatagattt caccatcttt
    11461 ttataatccc aattccatgg attaggataa ggaactatat ttccattctt atttttgact
    11521 aaatcacctg caaataatac atcttcaaaa atcatgcaga catgccctgg agtatgacca
    11581 ggagtatgga taatttttat attcccaatc ttcatattct ctccataagg ttcaacatcc
    11641 ttaatgagcc ttctggaaat tgcctttcca ataaacttct taaacccagg tctatccttc
    11701 tctcctataa taaaaggtat atcctctaca tgagcccata cctttgctcc tgttttctct
    11761 ttcaataatt taatattaga tatatgatca acatcatgat gagttaataa aatatgctta
    11821 atatctgtaa gtttaatgcc aagtgttttt aattctttaa ttatattttt ccccataaaa
    11881 ggaagacctg tgtctataag aataatttct ttatcaaaca caataaaaca atttgaacca
    11941 cgagtactat ctaacattaa tacattttct tttatcttca taaataaatt ccccttattt
    12001 ggtattttac ctatataatt aattaataaa gttataaata gttataatac ttgatattaa
    12061 ttttattttt tattaaagta tactataggt atacaaatat tatatttaca taaatatacc
    12121 atcagtatac ttttttatca atagaaagga ataatttata tgtcagaatt atcaaaaaga
    12181 gataaagaaa aaatacaaag agaaaatgag attattgata aggcagaaaa attattttgt
    12241 cttaatggat ttgattaaaa aatagctacg cacactcgtg actttagtca tgagtt
//
LOCUS       DACTZW010000109        11720 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.110, whole genome shotgun sequence.
ACCESSION   DACTZW010000109 DACTZW010000000
VERSION     DACTZW010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11720
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.110"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            231..2243
                     /locus_tag="JAM15_16835"
                     /pseudo
     CDS             231..2243
                     /locus_tag="JAM15_16835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888014.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
     gene            2612..3832
                     /locus_tag="JAM15_16840"
     CDS             2612..3832
                     /locus_tag="JAM15_16840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HAT6799918.1"
                     /translation="MQQALKLKYQTKELGKDFVIESCNSIKPWLINIRRELHKIPELA
                     LEENLTKQKVISYLKEIGIDYMEFTKHNGIMAYILKESADKTICIRADMDALPIEEEN
                     NIPYKSIHSGKMHACGHDAHTTMLLGACKVLHSIKDKLNVNVKFLFQPAEEGFGGAKF
                     LVEDGCLENPKVDYIFGLHVMPHIETGFIETKYDTLNASVDTIKICVKGKRAHGAYPE
                     NGIDAIVTASQIVTSLQTIISRNLEPNNAAVLTIGKIYGGDAHNVICEDVKLEGTLRT
                     LNSKTRNFMIDKISKIVEDTASAFGCVGTLHVSDENYPAVINEKELVDTVISSTKELL
                     GEEKFILRANPSLGGEDFSFYTEHCKGAFFHLGCKNEEKGLISPLHTSSFNIDEDCLP
                     IGVMMHVMNTLYFN"
     gene            3869..5218
                     /locus_tag="JAM15_16845"
     CDS             3869..5218
                     /locus_tag="JAM15_16845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAT6799919.1"
                     /translation="MEKAKKLGLFSMILLGINSIIGSGIFLLPGKVYNLAGQNSMFIY
                     IFATLLVLSILLCFAEVGSMFDKNGGAYLYSKKAFGDFIGFEVGTMSWVIRIISWSTL
                     AVGFATALGSFWPESATEYKGCIAAILVTLLSINSLFGIKSTKIMNNVITIAKLVPLI
                     VFVIVGIFFIKFVNIVPSGNVVNSSMGPAIILVFYAFTGFESFIVASGEMENPKKNLP
                     IALITTIFICAIIYILIQIVCMGILGDRLFENSIPIADASSVFLGNYGKVFISVATLI
                     SIFGINIGSSIVTPKCGSSLAEEGSLPAFIGKTNKYGAPYVAIIISLICCIPLVLTGS
                     FEQLAVMSVIARFAQYIPTCLSVIVLRKRTDVKASFKIPFGPVIPMVAILGSLWLLQQ
                     AWAEDISKPITQNRVLIGLGAMLLIAPLYIFMKKNKEIEHKNKSEDSKLYISREKIQ"
     gene            complement(5646..8152)
                     /locus_tag="JAM15_16850"
                     /pseudo
     CDS             complement(5646..8152)
                     /locus_tag="JAM15_16850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901674.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
     gene            complement(8161..8823)
                     /locus_tag="JAM15_16855"
     CDS             complement(8161..8823)
                     /locus_tag="JAM15_16855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6799920.1"
                     /translation="MSILEIKNLNKIYGKSETEVKALSQINLKINSGEFVVIVGKSGS
                     GKSTLLHIMAGLETPTNGDVIIDNINISSLDEKKRSALRKEKLGLIFQSYNLIPVLTV
                     EENIKLPTINIKNKDEAYINELMELLGIKDRRMYLPNQLSGGQQQRVAIARALVNKPS
                     IVFADEPTGNLDTKTESDVLSLLKESQKKYNQTIIMITHNIDITKYADRVIEIEDGFI
                     RE"
     gene            complement(10287..10754)
                     /locus_tag="JAM15_16860"
     CDS             complement(10287..10754)
                     /locus_tag="JAM15_16860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAT6799921.1"
                     /translation="MKFLNVLIVVEDIEKSKKFYYDILGLKVICDFGENVVLEGNISL
                     QEKKLWLEFINKSDSEVKFNGNDAELYFEEDNFDTFVERLSTMKDIDYVHLAIEHRWG
                     QRAIRFYDLDGHIIEVGETMSSVCRRFLDSGLSIDEVAKRMDVTVEYIESVLE"
BASE COUNT         4345 a         1509 c         1330 g         4536 t
ORIGIN      
        1 taatttaatc gaatagaaat gaaaaatata catacagttt aagttttaag caacaattag
       61 ggggatttgg tgacaagatt tttaattata agaaagaaag tgtcttaatg caacttttat
      121 aaagtcatta tagacacttt cttttttatt tgataaattt aaattatcaa aattatattg
      181 ctttatacaa ctattttgtt ggaaactatt tattatataa ggagaaataa atgaaaaaat
      241 cagtagctct ggtaaatgat agtagaaaag atttaataga ctttttagaa aataatttga
      301 aattagtttt tggagattct ataaatatta atagatactt cataaatgaa ataaatgata
      361 atgatattat aaatgatgat gtgatattag taatgtcagt agaaagatta gacaaaatta
      421 taaataatat actagataag aaaaaagtga ttgtggtaag aagaactttt aggtaagata
      481 aaatttataa tctactatct ttaccacagg gtacaaacgt tctaatcgta aatgattctg
      541 atgaaactac tctagaaact ataagtttat tttataaaat tggagtgact aatattagac
      601 caattccata tatgaatgat aataactata aaaatataaa aatagctata actccaggag
      661 ttccagaaaa agtacctagc tttatctcag atatatttga tttaggtcac agatatatag
      721 atatctctac atttatagaa ataataaatt tattacaaat tgattcaaag gaaatacaat
      781 ctaatctagt taaatactca gaagaaataa taagtttaga tactggtata aaagataaat
      841 ataaggaatt atttttaaaa atagaagaat tagatacaat attgaattta tcaaaagatg
      901 gtatattatt tacttcaaaa gatggtgaaa taaatacata taatagtaaa gtaaaagata
      961 ttttagacat aaatgaggat atatatggaa aatacattga ggatatattt gtagatagtt
     1021 taaaagtttt attgagtgag aaagagatac tagataaagt tgtcgtattc aataagaaat
     1081 atataaatgt aaataaaaaa aacatataca atagagatga aaaaatgggc acatattata
     1141 gtttacaaga aataacatac ataaaaaaat tagaacaaaa tctcactaaa aaattaagag
     1201 aaaaagggca aatagcaaaa tatacattta aggatataaa aacaaatagt cctaaaatgt
     1261 ttgaatgtat agatttagct aagaaggttt ctaaatctga cttaagcata cttatcagag
     1321 gtgaaagtgg aactggtaaa gaactcatag ctcagtctat acataacaac tcaaatagaa
     1381 aaaatcaacc ctttatagca gtaaattgtg cagccgttcc tgaaaattta ttagaaagcc
     1441 agctattcgg atatgacaag ggaactttta ctggaggtct aaaagatgga aaacaaggat
     1501 tatttgaact tgctaataat ggaacaatat tcttagatga aataggcgat atgcctttag
     1561 aattacaaac aaaactactt agagttcttc aagaaaagca gataatgcct gttgggtctc
     1621 acaatgtaat taatatagat gttagaatca tatctgctac aaataagaat ttagaacaaa
     1681 tgattgataa tagccaattt agagaggatt tatattatcg attaaataca attccaataa
     1741 atatacctcc tctaagagaa agaaaagaag acatattaat tattatggaa gatttaatta
     1801 ataagaaatt agtaatcaca ccagaagcaa aaaaacttat acaaaactat atgtggaaag
     1861 gtaatataag agaactccaa aatgttacat cctatttaaa cattatgtgt gaagatattg
     1921 tattagagaa agatttacct ccaaacttaa ggtcttcaga taacaaaaat acatcattaa
     1981 aactaaaata tagtaagaat gatatattga atatattaga gatactaatt ttaaataagg
     2041 aatcagatgt tggtattggt aggggattaa ttttaaaagc actactcgat aagaaccttc
     2101 aaattacaga aggaaaaatt aaaaaaatat ttgaatatct aaaaaaagaa gaacttataa
     2161 tttgtagttc aggaagatat ggaagtaaaa taactcaaaa aggagaagat ttttacaata
     2221 aattaaaata taaaggtcta taaaattata atttatcaaa caaagaaatc tattcaggat
     2281 taaagtactc cttcaatagt tttttttatt tttcaagtac cctaaaatta taacttattt
     2341 tgtacataaa taataggaat taataggaat aggataattt ttttatttcc tatttttttt
     2401 atataaacta gcatataaaa tatattttct tcaaaataat attttttact gaaaattgaa
     2461 actatgcaat cattttttat actatacata tagataaatg attatattta ttcaatattc
     2521 ttataaaaaa caaaattctc catcgaaaat tatggcataa taattgctta ttatattaat
     2581 aaaacaataa aaagcaattg gaggaataaa aatgcaacag gctttgaaat taaaatatca
     2641 aaccaaagaa ttaggaaaag attttgtaat agaaagttgt aattctataa aaccatggct
     2701 tataaacata agaagagaat tacataaaat tccagaatta gctcttgaag aaaatcttac
     2761 taaacagaag gtaatttctt atttaaaaga aatcggaatt gattatatgg aatttacaaa
     2821 acacaatgga attatggcat atattttaaa agaaagtgca gataaaacga tttgtataag
     2881 agcagatatg gatgctcttc ctattgaaga agaaaacaac ataccttata aatcaataca
     2941 ctctggaaaa atgcatgctt gtggtcacga tgcacataca accatgctac ttggagcatg
     3001 taaagtttta cattcaataa aagataaact taatgtaaat gtaaaattct tatttcaacc
     3061 agcagaagaa ggttttggag gagcaaaatt cttagttgaa gatggatgtt tagaaaatcc
     3121 taaggtcgat tatatattcg gacttcatgt tatgccacat atcgaaacag gatttatcga
     3181 aacaaaatat gatacattaa atgctagtgt cgatactata aaaatttgtg tcaaaggtaa
     3241 aagagctcat ggtgcatatc ctgaaaatgg tattgatgca atagttacag cttcacaaat
     3301 tgttacatca ttacaaacta taataagtag aaacttagaa ccaaataatg ctgctgtttt
     3361 gactataggt aaaatatatg gtggtgatgc acacaatgta atatgtgaag atgtaaaatt
     3421 agaaggcacc ttaagaacct taaatagcaa aacaagaaac tttatgattg ataagatatc
     3481 taaaattgtt gaggatactg catctgcatt tggttgtgtt ggaactttgc atgtaagtga
     3541 tgaaaattat cctgctgtta taaatgaaaa agaattagta gacacagtta tatcaagtac
     3601 taaagaatta cttggagagg aaaaatttat attgagagca aacccttctt tgggtggtga
     3661 agatttttct ttttacacag aacattgcaa aggggcgttc ttccatttag gatgtaaaaa
     3721 tgaggaaaag ggcttaattt cacctcttca tacctctagc tttaatatag atgaagattg
     3781 tttaccaata ggtgttatga tgcatgtaat gaatactttg tattttaatt agtacagtaa
     3841 ttaataaaag aataggagat aaattaatat ggaaaaagct aagaaattag gtctatttag
     3901 tatgatatta ttagggatta atagcataat aggttcaggt atattcttac taccaggtaa
     3961 agtttataat ctagcaggtc aaaacagtat gtttatatac atttttgcta cactcttagt
     4021 tctatcaata cttttatgtt ttgcagaagt tggaagcatg tttgataaga atggaggagc
     4081 atatctatac tccaaaaaag cttttggaga ttttatagga tttgaagttg gtacaatgtc
     4141 ttgggttatt agaattatat catggtctac tctagcagta ggatttgcaa cagctttagg
     4201 ttcattttgg ccagaatctg ccactgaata caaaggttgt atagctgcaa tactcgtaac
     4261 actactttca ataaatagct tatttggaat taaaagcaca aagataatga ataatgtaat
     4321 aactatagct aaattagtac cattaatagt ttttgtaata gttggaatat tctttataaa
     4381 atttgtaaat attgttcctt caggaaatgt agttaactct agtatgggtc cagccattat
     4441 attagtattt tacgcattta ccggctttga atcatttatt gtggcaagtg gagaaatgga
     4501 aaatcctaaa aaaaatcttc caatcgcatt aataaccaca atatttatat gtgcaataat
     4561 ttatatatta attcaaattg tctgtatggg tatacttgga gatagactat ttgaaaacag
     4621 tattccaatt gcagatgctt caagtgtatt tttaggcaat tatggtaaag ttttcatatc
     4681 tgtagcaaca ttaatatcta tatttggtat aaatataggt tcatcaatag taactcctaa
     4741 atgtggttct tctctagcag aagaaggttc tcttcctgca tttataggaa aaacaaataa
     4801 atatggtgct ccatatgtag caataataat atctttaatt tgttgtatac cacttgtgct
     4861 aactggaagt tttgaacaac ttgcagtaat gagtgtaatt gcaagatttg ctcagtacat
     4921 accaacttgt ttatcagtaa tagttttaag aaaaagaaca gatgttaagg cctcttttaa
     4981 gattccattt ggtcctgtta taccaatggt agctatttta ggtagcttat ggttgttaca
     5041 acaagcttgg gcagaagata tttcaaaacc tataactcaa aatagagttt taataggatt
     5101 aggggcaatg ttgttaatag ctcctctata tatatttatg aaaaaaaata aggaaatcga
     5161 gcataaaaat aaatcagaag attctaaatt atatatttcg agagaaaaaa ttcaataata
     5221 ttttacaaac tatttaaaaa ttatttttct aatactatag aaataattag aaatgaccta
     5281 agttttatta tttatataaa acttagatca tttttttcaa gtaactgtta aatattttaa
     5341 tataacttac tatctttaca acacttaata tttgttattt atcataaaca aggttattgt
     5401 attatcaata atttttaggt tacacttatt attagtcttg tgttaaaacg acagtagact
     5461 taagagtaga gttttattaa gccaatattt atatttgcta tacattgtac ccctattaca
     5521 ccatacatat aacttggata acttatttta tttttatttc taaattattt aaaatcaata
     5581 tctacaccat tatcgataat tgcaattaaa ttcatataaa acctctttaa tttataggct
     5641 gttcactata aagtctttat ttcttccata aaattttcat tttgaatttt attcaatgtt
     5701 tttagtgtag ttatcatgat tataggtact aaaataaata ctattaggat aatagcccct
     5761 ataaatttcc aatttattaa attgatactt tcaaaaggtt ttattattat acttcttaca
     5821 attaaaatag gtattataga tatacaaaag cttactataa tatatatata actttccaat
     5881 ttaacaattt tatttatttc atgttttgat attcctattc ctctaaatag tgcaaattcc
     5941 ctacttctgc tattaatact agtaactata gtattgcaac aattaaataa agataatata
     6001 actataattc cagttactaa taccataatt agtgtttttt gattatcaat tttttcatat
     6061 tcagctgttt cagctttgta tggaattaaa attcctttat ttgttttttc tgttatttta
     6121 tttaactcac tttcaacata tttatcattg gctagtttac tcgtccatat gtcaaatctt
     6181 tcataagatg atattcctgt aaacttatta aattgatttg ttgatattac tccgccaaat
     6241 tcagctccca cttgtgaggt tactggtaat gtagttacaa ttccacatac tataaattct
     6301 tgagatattg ttttggtaaa attgtttgtt tttgaatcta taatatcaaa gtatactttt
     6361 attctatctc ctttttttat attaagtgaa tcactggatt tctttgttat atacagatat
     6421 ggttgtttac taaattcatc tatattttcc tttccattta tcaagaaatc ctctagtata
     6481 tctgtatctt ctattcctaa aaattcaaaa gaattattat ataccttaat tccatctttt
     6541 acttctgatc tagcttcaat attatcttta ttttttttcc aataatcaga gttcttattt
     6601 atacttttat catcaatttt tatattaaac cacttatgcc tatatgagtt tacttttgtt
     6661 acaccatcaa tggcctttat ctcttgtagt acatttttat cataaccttt attatttgaa
     6721 cgtatagtac ttatatcaat attatgtaat aaataatctc cttgtatcca atattttaat
     6781 acaccatcac ttaaaaagtt actagtagac tttgtatata ttgttgccat taagaaaaat
     6841 ataattacca ttgatgctat agataaattt gtacgtttct tatttctttg tatatttttt
     6901 gatgctatgt taccatagtc tttgaaaagt tttatcataa atttatttat aaaggaattt
     6961 tgttttatat ccactttttc attatttctt cttatacaaa tcattggatc agttttaact
     7021 gataacataa gaggttttga aactgatatt attatagttc ctaaacttaa taatatagaa
     7081 attatgtatg tgtttatata gttctggttt tttatagaat ttatatagtt gacattgtat
     7141 attactccta taacatactc ccttgataaa ctagctatta tcccacctaa aattagacct
     7201 atagaaatac ttataataga gtatatagat acttctaaaa tcattatttt aaaaatatca
     7261 tttggattaa accctaaagc cctaaatatc ccaaaatcct ttattctatt tgatactaat
     7321 atataaaaaa tattataaat taataatata gttgctagtg ctagtactat attaactatt
     7381 atataaggta tttttaaatt catactatca gatatagcta ttaataattc attattaaaa
     7441 taaatgttat tctcattcaa atttccattt ttaataagtt tttgtgattg tctctgtata
     7501 ttttttcctt tttaaaagta aacataactt gatcatattt atttttagta ggaatattct
     7561 tgatagcaca atcgttactt ataaggccaa ttgatgtccc ttgagctttt aaaataggat
     7621 tactatttaa gataccagtt attttaaatt ctttttcccc agtatataaa tcttcttgat
     7681 ctatcccttg tcttctataa tctaatgtta tcctttttcc tatagggttt tttatctttt
     7741 tttgtttaat ataccatgaa tctatagcga tttcattttc atctactggt aatttacctt
     7801 tttctagtgt ataaatatca tttagttctt cagcaacttt atcctgagat agaatttgta
     7861 gtgtttgacc tttaccaata tcactaattc ctaaaagcat tgattttcca actttatcta
     7921 tacttgtgtt attttctata tattttattt cttcgtcttt tggattgata tattgtgcat
     7981 gttttaatgt aaatttattt ttagcttgat ttatcattaa gtttgtcgca tcttcactta
     8041 ttatattcat aattaaaaac aacgctgttg aaattacaat acttacaatt attaataatg
     8101 tatttttctt atttcccatt atatattttt ttacaatata attaagtttc ataaatctac
     8161 ctactctctt ataaatccat cttctatttc tataactcta tcagcatatt ttgttatatc
     8221 tatattatgt gttatcatta ttattgtctg attatatttt ttttgagatt cttttaataa
     8281 acttaataca tctgactctg tctttgtgtc taaatttcca gtaggttcat cagcaaatac
     8341 aattgatggt ttatttacaa gagcccttgc tattgctact ctttgttgtt gtccacctga
     8401 taattgattt ggcaaataca ttcttctatc ttttattcct agtaactcca tcaattcatt
     8461 aatataagct tcatctttat tttttatatt tatagttggt agttttatat tttcttcaac
     8521 agttaaaact ggaatcaaat tatatgattg aaatattaat cccaactttt ctttacgtaa
     8581 tgcagatctt ttcttttcat caagagatga tatatttata ttatcaataa tcacatcacc
     8641 atttgttgga gtttcaagtc ctgccattat gtgtagtaaa gtacttttcc cacttccact
     8701 tttacctact atcacaacaa attctccact atttattttt agatttattt gacttaacgc
     8761 tttcacctct gtttctgatt taccatatat tttatttagg ttttttatct ctaaaatact
     8821 cataatttac tccttgtctt acatgttatt tacacttatc aattttatag ctttacactt
     8881 gtatatgcgt ctataagctt atctttataa catccttttt tgttgtgtgt cttttatttc
     8941 ctattcaaat ccaaaatcag ctaaacagtt ttcatattgt ccatttactt ctaatatttc
     9001 taccttttta ctatatatac aatctgatat gttacctata ttataatttt ttagacctac
     9061 agcaaatgta cgcaaataaa tcttctatta tgtttagtgt aacattcact ctacaccttg
     9121 aatgttcaaa tattgagttc attttatgtg cagttttaat agctttatca aataatccta
     9181 tattattttt ataaattcga tttttgctat ggattttgca atctctatct atacttattg
     9241 atatgtagca acagaaacta tttttataat tttcaaaaaa ttcttccgcc tattcactcc
     9301 atatagtgcc tttagttatc ataccatatc ttataattga attttatttc ttatatctct
     9361 tttaccaacc tttttattta ggaaaagttc ttcaccatga aattgtacag tatataccta
     9421 tttctttgat tatataatta agctttttat ttagtaacct attttctaca tcctaactta
     9481 tatttcctgt ttcctcattt tcatatttat aacaatagtt acaatctaaa ttactacttt
     9541 tagttaccca gactttactt tacatgcttt gcctctaaac tgctgatgtt aatatcttct
     9601 taattttttc acacctatct tcaaatataa aatctttatc taaaagatta ttgtattcag
     9661 ctagacataa ccaacaaaat gatttcatta aatattcttt acattcatta ttacataact
     9721 ttaagttgaa aaactcatta tatccaaaat tcgttgatac ccatattatt aatataactt
     9781 acaatgtctt tttgaatatc taaaaaaata cttttataac ttattttata tatcatacac
     9841 tatattattg ctttcataat ctataaaggt ttcatatgat acaaacttct aagatgggat
     9901 ttttggtctt taataacgat tataataata tttatttata tttctgattt aaacattatt
     9961 ttacttgaaa tgtttattaa ataaatgaat taaaactaaa ctttcattat atttttaatt
    10021 tattcaatta aattttagca tagttatata aaatagtata tataattata caagataata
    10081 gtaaatataa ctatctttta tatatttttt ctaaatttaa actttagtat aaatatataa
    10141 gaaatatcat aatattttta aaaactcaaa taaagctaaa caagtattat attctttatt
    10201 ttagaaaaat aaaaactgta agcaaatttg ttttcacaca agtttactta cagccttcac
    10261 ctcaatttta ctttaatata atccatctat tctaaaactg attcaatata ttcgacagtt
    10321 acatccattc ttttagctac ctcatctatt gaaagaccac tatctaaaaa acgtctacac
    10381 acagatgaca tagtttctcc aacctcaata atatgcccat ctaaatcata aaatctaatt
    10441 gctctttgac cccacctatg ctctatagct agatgaacat aatctatatc tttcattgta
    10501 ctcaatcttt caacaaaagt atcaaaatta tcttcctcaa aatataactc agcatcattt
    10561 ccattgaact taacttcact gtcactctta ttaataaatt ctaaccaaag ctttttttct
    10621 tgtaatgata tattaccttc taatacaaca ttttctccaa aatcacagat tacctttaac
    10681 cccaaaatat cataataaaa cttttttgat ttctcaatat cttcaactac tattaaaaca
    10741 tttaaaaact tcatattacc tccttaatat acacatactt tatttataat atataattag
    10801 aattaaacta taaaggtttc aataaggtct agtataaaga aaaaaattat aagtcttatt
    10861 gaaatagtta agttaattta attttatcat ataatataaa ttttaatctt gtaaaaaaca
    10921 gacatgttca tacttttagg tttaaatcta tatgtattct tattaatttt gctaaaactg
    10981 ttatttttgt agactatttt agattactga aatatctatg tttttttaat ttcaagggaa
    11041 tattaatata cactaataat attaatatca cctttaaata ttacaagtat atgcatttta
    11101 tatgattaaa aagattattc aaatattata attaataaaa atatagtttt tagttcttct
    11161 aatttagttt tcataatctt tctaattatt gatattttat tacaaatact atatatatta
    11221 ctaataatta tatttactct ttaataataa ataaaatttt aattttaaat aaatttattt
    11281 ttgatattta tatttatttt tttgatatta acattacaaa ttcatcctaa tttttataaa
    11341 taaaataata aactaacttt ttaataaatt ttttgtatta ttttgtatat aggaaattat
    11401 tgaaatcata aaaaatcaac gttatattat aatcatatag taaattaaaa tcatttgatt
    11461 tatttaatta ttatttatta accagacgaa tgtaataatt attaaatata caatattaaa
    11521 atcaaagaga ataataaatg taatattaaa actcaataat aaatttatat tcataagttt
    11581 aatttcttca ttaattttat caactatgcc tctactgcct attaatttaa tgcaataaat
    11641 aataaatctt ttacaaaaag ataataaaaa tatagaaaaa tattttttat tgtccttttg
    11701 cttatggtaa accacattct
//
LOCUS       DACTZW010000110        11632 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.111, whole genome shotgun sequence.
ACCESSION   DACTZW010000110 DACTZW010000000
VERSION     DACTZW010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11632
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.111"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            355..537
                     /locus_tag="JAM15_16865"
     CDS             355..537
                     /locus_tag="JAM15_16865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799922.1"
                     /translation="MFKDKIDECVHIMTAYIASLKEYYSFIETQIGDFIKKYGEDVVE
                     LCLHRVMILLCECGLA"
     gene            1369..2283
                     /locus_tag="JAM15_16870"
     CDS             1369..2283
                     /locus_tag="JAM15_16870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2935 domain-containing protein"
                     /protein_id="HAT6799923.1"
                     /translation="MIDNQKYVILSLELHLFFSRIMKEHALFLEAGFTNKNYNLAMEA
                     DHYKKQFEDLLSYTVSASNGIIRPDILYSEELVTTLTSVAEQKTEEFTGIEINKNITT
                     RELNLQSGVNPQVGQDLVNYVAQLNSDAIRLLDGLINFKERVLDGVLSCTIFTSNYPL
                     LLEHIIHEANLYRSYVVDLENKIDIESKNAKEIELFWDHIMMEHALFMRGLLDPSEGE
                     LINTSNDFAIKFNELIEKTNEMTDSNIKNITEETLNETVEFKDFKEAGASGIEQCKIK
                     SIILPLLADHVLREANHYIRILESYKNM"
     gene            2673..3320
                     /locus_tag="JAM15_16875"
     CDS             2673..3320
                     /locus_tag="JAM15_16875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018999023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HAT6799924.1"
                     /translation="MIRQTPLEKRYDKLGPHIVTALKKRYFDAYYCKTRNEALQQILD
                     LIPQNHVVSWGGSETLKEMDVQTAVREKGFKVIDRDLAKTPEERTEIMRQALLCDTFL
                     MSSNAISEDGQLFNIDGNGNRVAAMIFGPKNVIVVAGMNKIVKNIDDAIQRTRTIASP
                     AVVQRFQDVNTPCYINGSCIDCTSPESICAYMVTTRISRPAKKIKVILVGENLGL"
     gene            complement(3487..4056)
                     /locus_tag="JAM15_16880"
     CDS             complement(3487..4056)
                     /locus_tag="JAM15_16880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799925.1"
                     /translation="MKKLIICIIMFAISVLVLAGCSNDNKIKNEVDSMFNAIKTQDAD
                     TVDKYFPKSGLGNLIYEDKEGFKMYSKNMTWEISDIKNNKDKVTVDLKINNTDMVSIL
                     KKNPPKLGEMMPNPTMKDIDSAKKKEFNITLELVKSGDNYVCKVNQESAMKLLNVITG
                     GGIDYLADYNKDYYKQLDEEQKNYENKNS"
     gene            complement(4061..4960)
                     /locus_tag="JAM15_16885"
     CDS             complement(4061..4960)
                     /locus_tag="JAM15_16885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HAT6799926.1"
                     /translation="MKLLSKVNNNIRLITQVAFTALTNGYVNGFLEGTIYGGESKKLC
                     VPGLNCYSCPGALGACPIGSLQAVLSSREYKFSFYVVGFLMAFGAFFGRFVCGWLCPF
                     GLVQDLLHKVPFPVKIKKVYGDKYLKYLKYIVLVMFVIILPVAIVNVAGGGNPWFCKW
                     ICPSGTLLGGIPLILGNENLRESIGFLFSWKLSILLLILLMSIITYRPFCKYICPLGA
                     IYGFFNPISIYRFKIDKDKCTNCTACQTKCKLDIPIYKDVNSPDCIRCGECIKVCPQN
                     AITTTFSKDKKENNICAKKYRGI"
     gene            complement(5113..5697)
                     /locus_tag="JAM15_16890"
     CDS             complement(5113..5697)
                     /locus_tag="JAM15_16890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HAT6799927.1"
                     /translation="MKKFFMVVLGCIFVLGVISGCSKKESKPVEKNKSNSEWFSNLDT
                     EDVDGNKVTKEIFSNKELTLINVWTTWCGPCVGEMPELEALSKEYESNNSNVAIKGLV
                     VEVDKTDMRTGLSNEEKNLVKNIMKKSDATYQQLTVSEELKKTDFKRVMEFPTTYFVD
                     KKGNFVGEKVVGANSKEEWKKIIDERLKMVKANE"
     gene            6119..7444
                     /gene="cdeA"
                     /locus_tag="JAM15_16895"
     CDS             6119..7444
                     /gene="cdeA"
                     /locus_tag="JAM15_16895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MATE transporter CdeA"
                     /protein_id="HAT6799928.1"
                     /translation="MENLFTRKFTTFEFLKFVSPAIISMIFISLYTIIDGIFVSTLVG
                     SDALASINIVLPIINLVCGFGIMMATGGGAIVSIRMGENRQDEANSTFSFIVLFSLIV
                     GILFTVISYFFIKEISILLGATDKLLPYCITYGKVMILCTPFYILKFIFEYFARTDGN
                     SKFSLFLSVIGGVTNIILDYVFIKYFGMGLLGAAVATAIGIILTCVLGIIYFLSNKST
                     LKLRKPKTDFRLIRDTMINGSSEMVTELSTGITTFLFNVVALKLAGENGLAALTIVLY
                     AHFLMTSVYLGFAAGVSPLISYNFGAENSDKLKETFKHSLKFIFVSSLLVFIIALVFA
                     PFIVRVFVSPDNTVFKLALQGLKIFAFAFLFVGINIFASGFFTAFHNGKISAIISFSR
                     AFVFIIIGIIILPPMLNMTGLWLTVPFAEVITIFISILFIKKYKGRYKY"
     gene            complement(7539..8333)
                     /locus_tag="JAM15_16900"
     CDS             complement(7539..8333)
                     /locus_tag="JAM15_16900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6799929.1"
                     /translation="MNELKPYIKFFNKNTKLYIIIFMIVGIVMNILPVFILKIFGEAS
                     KTNLSTIVNPILTYITILLFVYGVNIANKDFSGALSIRADRKSCIKAIVIDLIILSFV
                     ISILGIVLIFLSKLFIEIITGYSIELSVLLKRDMIWTSISALIDPSTSSMPLTYLNYF
                     VQICINEICIGFIGVLLGAFTYRVRKVTSITILIGLPILMVIYIVNFATKNMHKMLLY
                     LEKIIYSFQNPFILFGTKVGIIVICIIFIILLLRKAPIKEYANDLL"
     gene            complement(8334..9209)
                     /locus_tag="JAM15_16905"
     CDS             complement(8334..9209)
                     /locus_tag="JAM15_16905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6799930.1"
                     /translation="MSSSIKIENLSHSFKKQNIFNNMSLNFEKNKIYGLLGKNGAGKT
                     TLLNIMVNQLIQNEGEIEILGKNPKEDIKVLEEVCIVREKEFYSPDFKVGQIFEFSSS
                     FYKSYDKGLEKELCKYFDLNTKKKYKQLSRGMKTILSNIIGICSNSAITIFDEPTIGL
                     DAVNRQEFYNIILDSYIKNPRTIIISTHLIDEIDDLLEHVIILNEGKIIIDEEIDVIK
                     QKAHYITGNKEELEKLECIKNIKPKKAFGNAVAYFYYGDFSENDEKILKNSNIDVGYI
                     GLQDMFVNMTKKEEL"
     gene            complement(9213..9581)
                     /locus_tag="JAM15_16910"
     CDS             complement(9213..9581)
                     /locus_tag="JAM15_16910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAT6799931.1"
                     /translation="MKLVLNNEEPIFIQIARAIEDEILSNGIKEEEQVPSTTELSKLY
                     KINPATVLKGINILVDKNILYKKRGIGMFVSDGAKTIIKEARKENFKHNFVKNLLQEA
                     NKLEINREELVDIIINFKED"
     gene            complement(9764..10423)
                     /gene="deoC"
                     /locus_tag="JAM15_16915"
     CDS             complement(9764..10423)
                     /gene="deoC"
                     /locus_tag="JAM15_16915"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HAT6799932.1"
                     /translation="MKHILKTVDHTILKATTTWEDIKILCDEAVDMSVASVCIPPSYV
                     KRASEYLKGKIKICTVIGFPLGYQTTATKVFEAKDAIENGADEVDMVVNISDIKNKDY
                     DNIGKEIKEIKKAIGDKVLKVIIETCYLDEDEKIKMCEIVTMSGSDFIKTSTGMGTGG
                     ATLEDIKLMKEHVGKNVKIKAAGGVKSISDAEKFIEAGAERLGTSSICKILKNEDTTD
                     Y"
     gene            complement(10459..>11632)
                     /gene="murJ"
                     /locus_tag="JAM15_16920"
     CDS             complement(10459..>11632)
                     /gene="murJ"
                     /locus_tag="JAM15_16920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HAT6799933.1"
                     /translation="CDFSHGRFRTGIIFIGITSVMSAFLQIKENFIVVGFGSIPYNIV
                     IIISIMLSTIFGPYILPIGAVVAMVVQLLFYMFFVKKTNYKYLYYLNFKDDSLIKLLA
                     LLSPVFIGVAVNQVNSLVDTTLASTLVKGSIPALTYADRLNGFVTGTFTASIVSVMYP
                     MLSKLSAENNQKKFTSSVKSSINMIIISMIPISVASIFFATPVVRIIFERGAFDARAT
                     QMTATALIFYAVGMTAFGLRDILGKVFYSLQDTKTPMVNGIISVVVNIVLDLVLIKPM
                     AHGGLALATSSSSIACILLLFLNLKRKVGYFGQDKIIKATLKSVVASLIMGVLSYFTY
                     KFIFGILGVGTFNEFVSLAISVIVGGGIYTLLMIIFKVEEVDMILNIAKRKLHLKK"
BASE COUNT         4102 a         1766 c         1300 g         4464 t
ORIGIN      
        1 atacctaaaa aataataaat tgcttagaaa ataatagatt acaataacta aaattttaaa
       61 attaaattcc ttaaaagtat gattaattat aattatataa gtatattctt attacactta
      121 tattaattta tattaaatat ctactaactc aaatattcat aattaaactt taaactggat
      181 aaattttctt ttaagaatga aagtttatcc agttttgcga ttataataac cagttttaca
      241 tatccacttg taaaatatat ctaagcaata tatcatacta tatagattta tgagtgaaat
      301 aatatctgct atttactgaa tatttttatt tttcgttttt tagggggatt agttgtgttt
      361 aaagataaga ttgatgaatg tgttcatata atgactgcat atattgctag tttaaaagaa
      421 tactattcat tcatagaaac tcaaattggt gattttatta aaaaatatgg agaagatgtt
      481 gtagagttat gtctccatag agtgatgatt ctactatgcg aatgtggttt ggcataaaat
      541 taaatttatt aaaatgggta agaagaatcc tatataatat tcttcttacc cattttaata
      601 tatcaatttc atagcttatc gtttaaaata ttttacctcc attactagac aactttacat
      661 tctcttttta attctagtat atttaaatca ttttagttgc tccttattta ttcttattac
      721 ttgttttatt ttataaataa aataattctt tttaataatg ttttttgttg atattcctat
      781 cacacatcca attatttatc attgtcttga aattgtttgc atacttaatt taatccaatt
      841 gaaacacccc agcatagaat cccctgtaaa atagaagttg gattaaatcc taacatccat
      901 acagaaaata ctactccaag cacaagcaat ataatggaat atatttatca cttaattttt
      961 tatacttttt aaatcccata cctaaaacat taagtgcagc tattagaatt aataattgtt
     1021 gtggtataaa attatgattg cttcatattt attcattttt tgctataaaa gttcttgttt
     1081 cacaaaaaat atttgttttg tatcaaaata atacttataa attacataat tctcataaaa
     1141 atttctagta ttacttgtgc tcttaataaa taatagccaa caagtacctt aaatcattat
     1201 atctatatct aataagaaac acagtaagat aattttttcg cccataactt aataaaaact
     1261 gttgatatta gtagcaattg aatttagtta atttatttat aatatacata aatttaaata
     1321 ttacgaataa agtattataa ataggatact ttctaaaggg aggaaattat gatagataat
     1381 caaaaatatg ttattttatc actagaatta catttatttt tttcaagaat tatgaaagag
     1441 catgctcttt ttttagaagc aggattcaca aataaaaatt ataatcttgc tatggaagct
     1501 gaccactata aaaagcaatt tgaagattta ttatcataca ctgttagtgc tagtaatggt
     1561 ataattagac ctgatatatt atattcagaa gagcttgtaa ctactctcac atcagttgca
     1621 gaacaaaaaa cagaagagtt tacagggata gaaataaaca aaaacatcac tacaagagaa
     1681 ttaaatctac aaagtggtgt aaacccacaa gttggtcaag acttagtgaa ctatgtagct
     1741 caacttaact ctgatgcaat aagattactt gatgggctta ttaattttaa agaaagagtc
     1801 ttagatggtg tactatcatg tactatattt acatcaaact accctctact tcttgaacat
     1861 ataatacatg aagcaaattt atatcgttct tatgtagttg accttgaaaa taaaatagat
     1921 attgagtcaa aaaacgctaa agaaatagaa ttattctggg accatattat gatggaacat
     1981 gctctgttta tgagaggatt actagacccc tcagaaggtg aactaataaa tacttcaaat
     2041 gattttgcta taaaatttaa tgaattaatt gaaaaaacaa acgaaatgac tgattctaat
     2101 atcaagaaca ttacagaaga aactctaaat gaaactgttg agtttaaaga ttttaaagaa
     2161 gcaggagcat caggaataga acagtgtaag ataaaatcta taatattacc acttttagca
     2221 gaccatgttt taagagaggc aaatcattat attagaatat tggagagtta taaaaacatg
     2281 taattaaaaa ttacttttaa aataatcttt gcatatttag ataaaataaa ggtacagtta
     2341 actgtacctt tattttttat aaacttataa aatttaaaca agttattcat aaaataaaat
     2401 aatcatcatc tataacccac aactttattt tatattaaat aaaaagtatt agtgattatg
     2461 ttttataagt atttctttat tcagttattt gttaaaaact aatagtaaat cttatactaa
     2521 tcgtatattt atgttataac tatattgtaa ctattttcgt aatcttagga aaagattact
     2581 tataaaatta accttataca ataatatatc gtataatctt aattagcata atagttacaa
     2641 tattaaaatt taaatatggg agtgatttta gtatgataag acaaacacca ttagagaaac
     2701 gatatgacaa gctaggtcct catattgtaa cagcactcaa aaaacgttat tttgatgctt
     2761 attactgtaa aactagaaat gaagctttgc aacaaatttt agatttaatt cctcaaaatc
     2821 atgtagtatc atggggagga tctgaaacac ttaaagaaat ggacgtacaa actgctgtta
     2881 gagagaaagg atttaaagtt attgatagag atttagcaaa aactccagaa gaaagaactg
     2941 aaattatgcg tcaagcactt ctatgcgata cttttttgat gagtagcaat gcaattagtg
     3001 aagatggaca actctttaat attgatggaa atggcaatcg tgtagctgca atgatatttg
     3061 gtccaaaaaa tgttatagtt gtagctggta tgaataaaat tgtaaaaaac attgatgatg
     3121 caatacaaag aactagaaca attgcatctc cagcagttgt tcagcgtttt caagatgtca
     3181 atacaccatg ctatattaat ggaagttgta tagattgcac aagtcctgaa agcatttgtg
     3241 catacatggt tactacaaga atcagtcgtc cagcaaaaaa aataaaggta atattggtag
     3301 gagaaaatct tggtctataa aatatacata catgtaaata gctctataaa taataaaatc
     3361 atatgaaata acttatttct aaaagtggta gaataaaagc ttctacaaga ctttcattct
     3421 accactttta tattctttta atttgtgttt ctatattatt aattgctcca attttcatat
     3481 atattactaa ctatttttat tttcataatt tttttgttct tcatcaagct gtttataata
     3541 atctttatta tagtcagcta gataatctat accacctcct gtaatcacat ttaataattt
     3601 cattgcagat tcttgattaa ctttacaaac ataattatca ccagatttaa caagctctaa
     3661 tgtaatatta aattcttttt tctttgcaga atcaatatct ttcatagttg gatttggcat
     3721 catttctcct agtttaggag gattcttttt taaaatagaa accatatcag tattgttaat
     3781 ttttaaatct acagtcactt tatccttatt attctttata tctgaaattt cccaagtcat
     3841 atttttagaa tacattttaa atccttcttt atcttcgtat ataagattac ctaaccctga
     3901 ttttgggaaa tacttatcaa cagtatctgc atcttgtgtt tttattgcat taaacatact
     3961 atccacttca ttttttatct tattatcatt actacaacca gctaacacca gtactgatat
     4021 tgcaaacatt ataatacata taataagttt cttcattaaa ttatatcccc ctatactttt
     4081 ttgcacaaat attattttct tttttatctt ttgaaaaagt tgtagtaatt gcattttgtg
     4141 gacaaacttt tatacattca ccacacctaa tacagtctgg actatttaca tctttatata
     4201 ttggtatatc aagcttacat tttgtttgac atgctgtgca attcgtacat ttatctttat
     4261 caattttaaa tctatatatt gaaataggat taaaaaaacc atagattgct cctaaagggc
     4321 atatatactt gcaaaatggc ctataagtaa tgattgacat caataatatc aatagcaaaa
     4381 tacttaactt ccagctaaat aaaaatccta ttgattctct taaattctca tttcctaaaa
     4441 taagtggtat tcctcccaaa agtgttcctg aagggcaaat ccatttacaa aaccaaggat
     4501 ttccaccccc tgctacattt acaatagcaa ctggcaaaat aattacaaac attactaaga
     4561 ctatatactt tagatatttt agatatttat caccataaac tttttttatc tttactggaa
     4621 agggtacttt atgtagtaaa tcttgtacaa gtccaaaggg acaaagccaa ccacaaacaa
     4681 atctgccaaa aaaagcacca aatgccatta aaaaaccaac aacataaaat gagaatttat
     4741 actctctgct tgataaaact gcttgtaatg aacctattgg acatgctcca agtgcacctg
     4801 gacatgaata acaattcaat ccaggtacac ataatttttt actttctcct ccatatatag
     4861 ttccttctaa aaatccattt acatatccat ttgttaatgc tgtaaatgca acttgagtaa
     4921 taagtcttat attattattt accttagata ataacttcat tcctcttctc ctaaccaata
     4981 ccaatacact caagacaaat cataattgct ttagttaata ctgtatttgt ttctccacga
     5041 tatgtaccta atgcaataaa tataatacta attgcaataa tagaaatgcc ttttttatta
     5101 tctttaataa agttactcat tggcttttac catttttagt ctttcatcta taattttttt
     5161 ccactcttcc ttactatttg cacctacaac cttctcaccc acaaagtttc ctttcttgtc
     5221 tacaaaataa gttgttggaa actccataac tcttttaaaa tcagtttttt taagttcttc
     5281 agatacagtc aattgttggt aagttgcatc tgactttttc ataatgtttt taactaaatt
     5341 tttctcttca tttgaaagac cagttctcat atcagtttta tcaacttcta caactaatcc
     5401 ctttatagct acattggaat tattactctc atattctttt gataatgctt caagctctgg
     5461 catttcaccc acacatggtc cacaccaagt agtccagaca ttaataagag taagttcttt
     5521 atttgaaaat atctcttttg ttaccttatt tccatcaaca tcctccgtat ctaaattact
     5581 aaaccattca ctattactct tgtttttttc tactggctta gattcttttt tgctacatcc
     5641 agaaatcaca cctaaaacaa aaatacatcc taaaactacc ataaaaaact ttttcatatc
     5701 tcacactcct agaatttata tagtatataa aatggctgct tgaaataaaa ataacttctc
     5761 ttctatatta aaacattata tttaataaat aagaactaat ttaaaataag ttgtataaaa
     5821 gatatatagt taaaatctat ttcttttcag acaaaatctt atatatatat aataacttat
     5881 aaagcttaag attatataca tatatttcta aaaattttct taagaaacag ttattcctta
     5941 ctaatgcaat atacctattt ttactaatat aagtttatta attagcatta tactaattta
     6001 tcttaatatg attttttgtt gattttaagc tgtttatcgt ataaataaaa tttttcttga
     6061 ctatatagtt actatatagc ttattataga tagagagtaa taaaaggagg taaaatttat
     6121 ggaaaattta tttacaagaa aattcactac ttttgaattt ctaaaatttg tttctcctgc
     6181 aattatatcc atgatattta tatctttgta cacaataata gatggcatct ttgtatcaac
     6241 attagttggt tctgatgctc ttgctagtat aaatattgta ctacctataa ttaaccttgt
     6301 ttgtggattt ggaataatga tggcaacggg tggaggtgct atcgtttcta tacgtatggg
     6361 tgaaaataga caggatgaag ccaactctac attttctttt atagttttgt tttcattgat
     6421 tgttgggatt ttattcacag taatctcata tttctttatc aaagaaatat ctattttgct
     6481 tggtgcaaca gataagttat taccatattg tataacttat ggtaaagtta tgattttatg
     6541 tacaccattt tatattttaa aatttatatt tgagtacttt gcaagaactg atggaaattc
     6601 taaatttagt ttatttctat cagtcattgg tggtgtaaca aatataatat tggattatgt
     6661 atttattaaa tattttggaa tgggtctttt aggagctgca gttgcaactg ctataggtat
     6721 tattttaact tgtgttttag gtattattta cttcttatct aataaatcta cactcaaatt
     6781 aagaaaacca aaaaccgatt ttagacttat aagagatact atgataaacg gttcttctga
     6841 aatggttaca gaattatcta caggaattac aacattctta tttaatgtag tagctttaaa
     6901 attagcagga gaaaatggac ttgctgctct tactatagta ttgtatgctc attttttaat
     6961 gacatcagtc tatctaggat tcgctgctgg agtgtctcca ttaataagct ataattttgg
     7021 tgctgaaaac agtgataaat taaaagaaac atttaaacat tctctaaaat ttatatttgt
     7081 ttcttctctt ttagtgttta ttattgcttt agtatttgca ccatttattg ttagggtctt
     7141 tgtaagtcca gataacacag tatttaaact agccttacaa ggattaaaaa tatttgcatt
     7201 tgcttttttg tttgttggta taaatatatt tgcatcagga ttttttacag catttcacaa
     7261 tggaaaaatt tcagctatta tatcttttag tcgtgccttt gtttttataa tcataggaat
     7321 cataattctt cctcctatgt taaacatgac tggattatgg cttacagttc catttgctga
     7381 ggttataacc atatttatat ctattctatt tataaaaaaa tataaaggta gatataagta
     7441 ttaaaaatta atgcttaaaa tcaacattta ttaaaactaa taaacctgct ttaaaataca
     7501 aatttacaaa tttgattttt aagcaggttt tattttagtt ataataagtc atttgcatac
     7561 tctttaattg gtgcttttct aagtaataaa attataaata ttatgcaaat aactataatt
     7621 cctacctttg ttccaaataa aataaaagga ttctgaaatg aataaataat tttttctaaa
     7681 tacaatagca ttttatgcat atttttagtt gcaaaattaa ctatataaat taccattaat
     7741 attggtaatc ctatcaatat agtaatacta gtaacttttc taactctata tgtaaaagct
     7801 ccaagtaaca ctcctataaa acctatacat atttcattta tacatatttg tacaaaataa
     7861 tttaaataag ttagtggcat acttgatgtt gaaggatcta tcagtgctga tatagatgtc
     7921 caaatcatat ctctctttag taaaactgat agttctatac tgtaacctgt tataatttct
     7981 ataaataact tcgataaaaa aatcaaaact atacctaaaa tagaaatcac aaagcttaaa
     8041 ataattaaat ctatgacaat agcttttata caactttttc tatctgctct tatacttaaa
     8101 gctcctgaaa agtctttatt tgctatattt actccataca caaatagcag tatagttata
     8161 tatgttaaaa taggattcac aatcgtggat aaattagttt tagatgcttc tccaaaaatc
     8221 ttgaggataa acactggcaa aatattcata acaattccca caatcataaa tataattata
     8281 tataatttag tatttttatt aaaaaatttt atatatggct ttaattcatt caattacaat
     8341 tcctccttct tagtcatgtt aacaaacata tcttgtagcc ctatgtatcc tacatcaata
     8401 tttgaatttt taagtatttt ttcatcattt tcactaaaat caccatagta aaaataagca
     8461 actgcatttc caaatgcctt tttaggtttt atatttttta tacattctaa tttttctaac
     8521 tcttctttat ttccagtaat ataatgagct ttttgtttta tgacatcaat ttcttcatct
     8581 ataataattt ttccctcatt taatattatt acatgctcca gtaaatcatc tatttcatca
     8641 atcaaatgag ttgatattat tattgtcctt ggatttttta tataactatc taaaattatg
     8701 ttataaaact cttgtctatt tactgcatcc agaccaattg ttggctcatc aaatatggtg
     8761 atagctgaat tagaacaaat acctattata tttgaaagta tagttttcat acctcttgac
     8821 agttgtttat actttttttt agtatttaaa tcaaaatatt tgcataattc tttttctaag
     8881 cctttatcat aacttttata aaaactagaa gaaaattcaa atatctgacc tactttaaaa
     8941 tctggactat aaaattcttt ttccctgaca atacaaactt cttccaaaac ttttatatct
     9001 tcttttgggt tctttcctaa tatttctatc tcaccttcat tttgaattaa ctgatttacc
     9061 attatattta ataatgttgt ttttccagct ccattcttac ctaataaacc atatatctta
     9121 tttttttcaa agtttagaga catattatta aaaatatttt gcttcttaaa actgtgagat
     9181 aaattttcta tcttaataga actactcata tattaatcct ccttgaaatt aattataata
     9241 tcaaccaatt cttctctatt tatttctaat ttgttagctt cttgaagtaa gttttttaca
     9301 aaattatgtt taaaattttc ttttctagct tcttttataa tagtttttgc accatctgat
     9361 acaaacatcc ctatccccct cttcttatat aaaatatttt tatcaaccaa tatatttata
     9421 ccttttaata ctgtagctgg attaatttta taaagctttg aaagctctgt tgttgatgga
     9481 acctgttctt cttcttttat tccatttgat agtatctcat cttcaattgc tcgtgctatc
     9541 tgaataaata taggttcttc attatttaat actaatttca taggttcctc ctttctccat
     9601 tagttagtta ctcaactaat taactatata acttataata tcttgaaaaa tattttctgt
     9661 caatactaaa taaaaaacag agggaaaatt ccctctgttt tttgttcttt atatttataa
     9721 ttaaattttg atttttgtaa tcctatccca taagttaaaa actttaataa tctgttgtat
     9781 cttcattttt taatatttta catattgagc tagttcctaa cctttctgct cctgcctcta
     9841 taaatttttc tgcatcagaa attgatttaa ctccccctgc agcttttatt tttacatttt
     9901 ttccaacatg ctctttcata agctttatat cttctaaagt agctccacct gttcccattc
     9961 cagtagatgt ttttataaaa tctgaacctg acattgttac tatttcacac atttttattt
    10021 tttcatcttc atctaaataa catgtctcta taatgacttt taatacttta tctcctatag
    10081 ctttttttat ttcttttatt tcttttccta tattatcata atctttattt tttatatctg
    10141 aaatgtttac aaccatatca acttcatctg ctccattttc aatagcatct tttgcttcaa
    10201 atacttttgt agcagtagtt tgatatccca aagggaaccc tatcactgta catatcttta
    10261 ttttaccttt tagatattct gatgctcttt tcacatatga tggtggtatg caaactgatg
    10321 ctacactcat atctacagct tcatcacata aaattttaat atcttcccat gtagttgtag
    10381 cttttaaaat agtatggtct actgttttta atatatgttt cataaaatcc tcctaaattt
    10441 ataattaata taattagatt acttttttaa atgcaatttt ctctttgcaa tgtttagtat
    10501 catatcaacc tcttcaactt taaaaataat cattagtagt gtataaattc cacctccaac
    10561 tataactgaa atagctagtg atacaaactc attaaatgtt cctactccca aaattccaaa
    10621 tataaattta tacgtaaagt atgataaaac acccataatt aaagatgcaa ctaccgattt
    10681 caaagttgct tttattattt tatcttgtcc aaaatatcca acttttctct ttaggttcaa
    10741 aaagagtaac aatatacatg caattgatga tgaactagtt gcaagagcaa gaccaccatg
    10801 agccattggt tttattaaaa ctaagtccaa tactatattt accactacag atataatccc
    10861 atttaccata ggtgtttttg tgtcttgtaa tgaataaaaa acctttccca aaatatctct
    10921 taagccaaat gcagtcatac caactgcata aaaaattaag gcagttgctg tcatttgggt
    10981 tgccctcgca tcaaaagcac ctctctcaaa aatgattcta acaacaggag ttgcaaaaaa
    11041 aatagaagca actgaaatag gaatcataga aattattatc atatttatac tagatttaac
    11101 tgaactagta aacttctttt gattattttc tgcacttaac ttagataaca taggatacat
    11161 aacagatact attgaagctg taaatgtccc tgtaacaaaa ccatttaatc tatctgcata
    11221 agtaagtgct ggaatgcttc ctttaactaa tgttgaggct aaagttgtat ctaccaatga
    11281 gttcacttga ttaacagcaa cacctataaa tactggtgaa agtaatgcta gtaatttaat
    11341 aaggctatca tctttaaagt ttaagtagta taagtatttg tagttcgttt ttttaacaaa
    11401 aaacatgtaa aagagcagtt gaactaccat agcaaccaca gcaccaattg gaagtatgta
    11461 tggtccaaat atggtactta acattattga aataattatt actatattat agggtatact
    11521 tccaaatcca actacaataa agttctcttt aatttgtaaa aatgctgaca taacacttgt
    11581 aatacctatg aatattattc ctgttctgaa cctcccatga ctaaagtcac ag
//
LOCUS       DACTZW010000111        11590 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.112, whole genome shotgun sequence.
ACCESSION   DACTZW010000111 DACTZW010000000
VERSION     DACTZW010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11590
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.112"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            30..1034
                     /locus_tag="JAM15_16925"
     CDS             30..1034
                     /locus_tag="JAM15_16925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HAT6799934.1"
                     /translation="MRFKRILILMLTVAMIAGMLVGCANNPSNNPSSSKDNKSDISDK
                     SNSKKSVSMILDIEGTNNEAMNNAALLALNNAQKKLNIDTNKVESDDSSTFSNSIDIL
                     CNDNYDLIIAVGARFAKPLEMVAKKYPKQQFAIIDYEYDKQPSNITSISYEDNKSGYL
                     AGLIAGKMTESDKVGFIGGIKSSSRDKFESGFREGVKFSNSSIKDISVEYADVFKDSK
                     SVESIAKKMMDNGVDIIFSTTEDDSKAVIDAVRAKNKKVIATNKDQHELAPENVISSI
                     VKDFENPTYNLIQSFVKGNYKGGKVIENTVKSGSTGLAQNSSQNIPPDVLEYVNKNNK
                     "
     gene            1180..2271
                     /locus_tag="JAM15_16930"
     CDS             1180..2271
                     /locus_tag="JAM15_16930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HAT6799935.1"
                     /translation="MACFVVVFTIFILAICNFDFGFDKVNKNNSNIDSAKSKQSESKS
                     VPTSAEKDKLNSKSKNEEDDTEDDSYVRKTIGVLLDTENLNNESYNNNVLSALKRADE
                     DFDVRIKLEKPKTSKSFKESIEKLHKYEPDLIIAVGARFAEPIKEAATKYPKQQFAIV
                     DYTYKVQPANVISVSFQDNVTGYLAGLIAGKMTDTGKVGFIGGVEGSSRDKYESGFRK
                     GLKTSNKDAELLVKYSNIFENPESARTIAKEMRDSDRDVVFSATEDDSKRAIQVAREN
                     GGKVIAINKDQYDMAPDNVISSIIKDVEQPVYELIKNVAKDGFKGSKVMEFKIKDGEL
                     GLTSKSSRNIPPDVLEYIKKEYNKVKDTY"
     gene            2694..3455
                     /locus_tag="JAM15_16935"
     CDS             2694..3455
                     /locus_tag="JAM15_16935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799936.1"
                     /translation="MEFTREPFILDDDLCLALVDKRISYLMENELKLRNIEIIKTIEC
                     KELYESIKYHPDICICNLGKGDIIVAPNVYNQYKELLSRYKFNIIKGEANLLNRYPYD
                     IPYNIAIVGDYAIHNFKYTDKAILDYIENNKLKKINIEQGYSKCSICIVDRTSIITSD
                     KGIWKSMKNTEIECLLIEKGHINLFEMNYGFIGGCTGLISKDKLAFCGDVKKHPDYER
                     IKSFVESKNKEIVTLSCENLLDIGSIVPLMTRKER"
     gene            3458..4276
                     /locus_tag="JAM15_16940"
     CDS             3458..4276
                     /locus_tag="JAM15_16940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799937.1"
                     /translation="MVEKDNISSMKFLRNNNVNDRLIYTNDIVEVVIDSAKQEVLNKK
                     ILNGTKAEQRALNIDEISTEITSMIISIMKEKLLKEYILKCYGRTYPEDKNNIYIYSL
                     NIFAKKEIFMRETVFTRVRNYIEENDFINVEGFIRFRMREFMKYISAIGDIAVEEYLI
                     KKDQDEFIRVLKYFIDTQEEKIDLLKVHIMEDNTFVLYDKNGNKIDSIDDEEIINMVI
                     RENLNYEDFLISTLLTLCPKKIEILDLLNNNCSKEIIDTVEAIFENKVSIIMEN"
     gene            4456..5058
                     /locus_tag="JAM15_16945"
     CDS             4456..5058
                     /locus_tag="JAM15_16945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF445 family protein"
                     /protein_id="HAT6799938.1"
                     /translation="MDNLIRILILAVIGGFIGYVTNVVAIRLIFRPIEPIKIPILNIE
                     IVGLIPKRRAEIAANVGEIIQEEFLSMDEILANIITDEDKEEVVRYIKARVKIIIHEK
                     VSFIPSGIKNMIQDYLGEIIESEVKQSIDELSKNIINKANERIDIQKMVEDKINELDL
                     YELEEIIIRIAKKELKHIEFLGLVLGFLIGIAQGLITMFI"
     misc_binding    5619..5851
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5915..7834
                     /gene="thrS"
                     /locus_tag="JAM15_16950"
     CDS             5915..7834
                     /gene="thrS"
                     /locus_tag="JAM15_16950"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HAT6799939.1"
                     /translation="MIKVALKDGSIKEFENAISVMDVAKSISEGLARNVVAASVNGEV
                     VGLDHIIDTDCDLNLFKFEDKEGKEVFRHTSAHILAQAIKRLYPEAKLAIGPSIENGF
                     YYDIDLDHRLVPEDLEKIEAEMKKIAKEDLKIERFELPRNEALELMKEQGEDYKVELI
                     SDLPESEIISFYKQGDFTDLCRGPHLPSTKKVKAVKLQSVAGAYWRGDENNKMLQRIY
                     GTSFEKNKDLEEYLHLLEEAKKRDHRKLGKELGLFMIPEEGPGFPMFLPKGMELKNEL
                     LKFWREIHRKAGYIEIESPIILNRKLWETSGHWYHYKENMYTVKIDDEDYAIKPMNCP
                     GGLIYYNSQLHSYRDFPMRVAELGRVHRHELSGALQGLMRVRAFTQDDSHIFMLPEQI
                     KDEIKGVANLIDGIYKTFGFEYNLELSTRPENSMGSDEEWEAAENGLREALEELGLPY
                     TINEGDGAFYGPKIDFHLKDCLGRTWQCGTIQLDMQLPRQFDNTYIGQDGEKHRPVMI
                     HRVAFGSIERFIGILIEHYAGKFPVWLSPTQVKILPISDKFMDYANEVKKELFDKGIR
                     VELDDRAEKIGFKIREAQLEKVPYMLIVGEKEVADNNVSVRSRDKGEIGSIKLDEFIA
                     SISKEIESRESIIQD"
     gene            complement(8321..8530)
                     /locus_tag="JAM15_16955"
                     /pseudo
     CDS             complement(8321..8530)
                     /locus_tag="JAM15_16955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888362.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(8523..9209)
                     /locus_tag="JAM15_16960"
     CDS             complement(8523..9209)
                     /locus_tag="JAM15_16960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799940.1"
                     /translation="MLDKIRTYIDSSFTGVNETKKVKELKDELFENLKEKYNDQIQDG
                     KTEQEAYNSVISGIGDLSELIESVKEPYSLPSELIEEKKKRALRASIAVTLFIISPFL
                     FVVSVVSFGIEPTIAILLMLILIALGVGLLVYNQMTRTNYALYNDNLSNKFKESEDFE
                     ENYNHINPVYKSFMNAYWIIIVSIYLITSILFNIWSFSWILFIIGVAGINIVKGIIQL
                     KGYKEEDKYE"
     gene            complement(9221..9541)
                     /locus_tag="JAM15_16965"
     CDS             complement(9221..9541)
                     /locus_tag="JAM15_16965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017751824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6799941.1"
                     /translation="MIIASDMIRGHTETIILKHLLEKDSYGYEINKSILEKTKGLYEL
                     KEATLYTAFRRLEQSGAITSYWGDEVTGARRKYYSITSIGKEKYIKSREEWNNTKALI
                     DILI"
     gene            9902..11242
                     /locus_tag="JAM15_16970"
     CDS             9902..11242
                     /locus_tag="JAM15_16970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAT6799942.1"
                     /translation="MIKSSLFWNIFIAISFMIEWFLCKKMLDYTSEKRISNKKINFCM
                     VGIIVFADIIYFFDVPPNIRVIISMIITIAFYKISYDVGFIKSVLISLIYWMLLIATD
                     ALSISLTVWLNSINDMSSMGTGDIYRIESIILGKILLIVSLFLYRALKIKLNIEINKR
                     TLFYIVIPIVANIASFFVIFEYIFNPGSGSLIHNFQFVMISVVLLISSITLVLIAKKL
                     QQYNTLVVENNMIKNTLKYENEYYEDIEKKYLKTRLLSHDMKNHILCINAMIKKGIDV
                     TSYLNNLQVEIQSNDLLFNTGNFILDAILSEKKEVCDKNDIELKIGINFSCCEAVELV
                     DICHIFSNILDNAIEACNKIDSGNRVICVKGDVMQNFYLIRVENTKINKIITKNGDIL
                     TDKKGSLHGLGIKSVKNSVNKYGGNVVIEYDDKKFVVKIAIPLRNVKKAVNHVI"
BASE COUNT         4570 a         1152 c         1975 g         3893 t
ORIGIN      
        1 tatcgtaaat gtatgaggag tgaaatttaa tgcgtttcaa aagaatattg atattgatgt
       61 taactgtagc aatgatagct ggaatgttgg ttgggtgtgc taataaccca agcaataatc
      121 ctagctctag caaagataat aaaagtgata taagcgataa aagtaattca aaaaaatctg
      181 tatcaatgat actagatatt gaaggaacaa ataatgaagc tatgaataat gcagctttat
      241 tagcattaaa caatgctcaa aagaaactta atatagatac aaacaaagtg gaatcagatg
      301 attcctcaac tttttctaat agtatagata ttttatgtaa tgacaattac gatttaatta
      361 tagctgtagg agctagattt gcaaaaccat tggagatggt agccaagaaa tatccaaagc
      421 aacaatttgc aattatagac tatgagtatg acaagcaacc ttctaatata acttcaattt
      481 cttatgaaga taataaatct ggatacctag ctggattaat tgctggaaaa atgactgaaa
      541 gcgataaggt tggttttata ggaggaataa agagttctag tagggataaa tttgaatcag
      601 gttttagaga gggtgttaaa ttttctaata gtagtataaa ggatatttca gttgagtatg
      661 cagatgtttt taaagatagc aaatcagtag aatctatagc taaaaaaatg atggataatg
      721 gagtggatat tattttttct actactgaag atgattcaaa agctgtaata gatgcagtaa
      781 gggcaaaaaa taaaaaagtt atagcaacga ataaagacca acatgagtta gctccagaaa
      841 atgttataag ttctattgta aaagattttg agaatcctac ttataatctg atacaaagtt
      901 ttgtaaaagg aaattataaa ggcggaaaag ttatagaaaa cacagttaag tctggaagta
      961 ctgggcttgc ccaaaatagt tctcaaaata ttcctccaga tgtgttagaa tatgttaata
     1021 agaacaataa ataatctact ataatatcca agaatactta tgactttagt tatgaggtga
     1081 attggatgtt ataatagaca tatatagaaa gacgtatgca gaggtaggca gacctatcta
     1141 aatcagggag tgaattttgt gaaaataaaa aggatattga tggcttgctt tgtagtagtt
     1201 tttacaattt ttatattagc tatatgtaac tttgattttg gatttgataa agtaaataag
     1261 aataattcta atatagatag tgctaaatcg aaacagagtg agtctaaaag tgtaccaact
     1321 tcagcagaaa aggataaatt aaatagtaaa agtaagaatg aagaagatga cacagaagat
     1381 gattcatatg taagaaaaac tattggagta ttgttagata ccgaaaactt aaataacgaa
     1441 tcatataata ataatgtact atcagcctta aaaagggctg atgaagattt tgatgttagg
     1501 ataaaacttg aaaaaccaaa gacttctaaa agttttaaag agagtataga aaaactacat
     1561 aagtatgaac cagatttgat aatagcagtt ggagctagat ttgcagagcc aattaaagaa
     1621 gctgctacta aatatcccaa acagcaattt gcaatagttg actatactta taaagttcag
     1681 ccagctaatg taatttctgt atcatttcaa gataatgtta ctggatattt agcagggctt
     1741 attgcaggta aaatgactga tactgggaaa gtcggtttta taggcggagt tgagggttct
     1801 agtagagata agtatgaatc tggatttaga aaggggctta aaacttcaaa taaagatgct
     1861 gagttactag ttaagtattc aaatatattt gaaaaccctg aatcagctag aactattgca
     1921 aaggaaatga gagattctga tagagatgtt gtattttcag ctacagaaga tgatagtaaa
     1981 agagctattc aggtagcaag agaaaatggt ggtaaagtta tagctattaa taaagaccaa
     2041 tacgatatgg ctccagataa tgtaataagt tcaattataa aagatgtaga acaacctgtc
     2101 tatgaactga taaagaacgt tgcaaaagat ggttttaagg gaagtaaagt aatggaattt
     2161 aaaataaaag atggagaact tggcttgact tcaaagagca gtagaaatat accaccagat
     2221 gttttggaat acataaaaaa agagtataac aaagtgaaag atacatatta attattgatg
     2281 tagaagatta taaaaatata ctgtttaagt ttagattagc aataaaaaga tatatttatt
     2341 aaatttgtgc taactgtaca aaatatattg attaagttta gattggtgat aaaaagatat
     2401 atttattaaa tttagtctaa ctgtacaaaa tatattgatt gagtttagat tagcaataaa
     2461 aagatatatt tattaaattt gtgctaactg tacggaatat actgcttaag tttagattag
     2521 tgataaaaag atatatttat taaatttgaa ccaactgtac aaagctatac taattaagct
     2581 tagattaact atataaaatt ataacaataa gtgtgtgggc agaaaaattc tgctacacac
     2641 tttatttata ttcatataaa aaaattatca aaaaaaagaa aaaggagtaa aaaatggaat
     2701 ttacaagaga accatttata ctagatgacg atttgtgtct agctttggtg gacaaaagaa
     2761 ttagttatct aatggaaaat gaattaaaat taagaaatat agagataata aaaacaatag
     2821 aatgtaaaga attatatgaa agcataaaat atcacccgga tatatgtatt tgtaatttag
     2881 gaaaaggaga tataattgtt gcgccgaatg tatataatca atacaaagag ttattaagta
     2941 gatataaatt taatataatt aagggagaag ctaatttatt aaatagatac ccttatgata
     3001 taccttacaa tattgcgata gttggtgact atgctataca caattttaag tatactgaca
     3061 aagcaatatt agattatatt gaaaataata aacttaaaaa gataaatata gagcagggct
     3121 attctaaatg ctcaatctgt atagtagata gaacgtctat aataacatca gataaaggta
     3181 tttggaaaag tatgaagaat acagaaatag agtgtttatt gatagaaaaa ggtcacataa
     3241 atttatttga gatgaattat ggatttatag gtggatgtac agggttgatt tctaaggata
     3301 aactagcttt ttgtggagat gttaaaaaac atcctgacta tgaacgtata aaaagttttg
     3361 tagaaagtaa aaacaaggag atagttacac ttagctgtga aaatttacta gatataggtt
     3421 ctatagttcc tctcatgaca agaaaggagc gataactttg gttgagaagg ataatatttc
     3481 ttccatgaaa tttttgagga ataataatgt aaacgataga ttaatatata cgaatgacat
     3541 tgtagaagta gtgatagatt ctgcaaagca agaagtgtta aataaaaaaa tacttaatgg
     3601 tactaaagct gaacaaagag ctttaaatat tgatgagata tcaacggaaa taactagtat
     3661 gataataagt ataatgaaag agaaactttt gaaagaatac attctaaaat gctatgggcg
     3721 tacatatcct gaagataaaa ataatatata catatattca ctgaacatat ttgctaaaaa
     3781 agagattttt atgagagaaa cagtatttac tagggtgaga aattatatag aagaaaatga
     3841 ttttataaat gtagaaggtt ttattagatt tagaatgaga gaatttatga aatatatttc
     3901 tgctataggt gatattgcag ttgaggagta tttaataaag aaagaccaag atgaatttat
     3961 aagagtttta aaatacttta tagatactca agaagaaaag attgatttgc ttaaagttca
     4021 tataatggaa gataatacat ttgttttata cgataaaaat ggaaataaga tagacagtat
     4081 agatgatgaa gaaattataa atatggtaat aagagaaaat ttaaattatg aggacttttt
     4141 aataagtacc ttattaactc tatgtcccaa aaaaatagaa atattggatt tgttaaataa
     4201 taattgctca aaggaaatta tagatactgt agaagcaatt tttgaaaata aagttagtat
     4261 aattatggaa aactagaatc taagcatata aaagctagcc atataaaatt aaaaaaattc
     4321 tttttaaatc gacacaaaag acttataatt gtatataaag ctatagtata actagagtta
     4381 ttaagtataa agaatatcta cttgattaat gcaatatagc tggcaaatat acaattgata
     4441 aggagtaatt ttataatgga taatttaatt aggatactga tattagctgt tattggtgga
     4501 tttataggtt atgttacgaa tgtagttgct ataagactga tatttagacc aatagagcct
     4561 attaaaatac ctattttaaa tatagaaata gtaggtctta taccaaagag aagagcagaa
     4621 atagcagcaa atgtaggaga aataattcaa gaagaatttc tttctatgga cgaaatactt
     4681 gcaaatatca ttactgacga agataaggaa gaagttgtaa gatacataaa agcaagggta
     4741 aaaattataa tacatgagaa agtttcattt atcccgagtg gtataaaaaa catgatacaa
     4801 gattatctag gagagataat tgagtctgaa gttaagcaaa gtatagatga attgagtaaa
     4861 aatataataa ataaagcaaa tgaacgtata gatatacaaa aaatggtcga agataagatt
     4921 aatgaactag atttatatga attggaagag ataataataa gaatagctaa gaaagaatta
     4981 aaacatatag agtttttggg gcttgtctta gggtttttaa taggtatagc tcaagggtta
     5041 attactatgt ttatttaaat atatgagaag tagcatttat ttaagtacta attatattta
     5101 cctatttgag tgaattactt attaatagta tttagatatt aattgtattt acctatttga
     5161 gtgaattact tattaatagt atttagatat taattgtatt tacctatttg agtgaattac
     5221 ttattaatag catttagata ttaattgtat ttatttattt gattgtgtta cttattaata
     5281 gtatttaagt atttactgta ctacttatta actatattaa gtattgattg tatttaagta
     5341 tacaaaacct aaaaagagta caaaaattag aagttagttt taataaaaat tagttttagt
     5401 atttatctag tcatatctat catgcatgtg gatacgtttt aaaaatttta aatttatgaa
     5461 aatattataa tatcactata aatcaagaga ttaatttaat ataaaaatat aagaatattg
     5521 gtttacagct gattgagatg aaaaataatg ggtaattaat atattacatt aatgttgatt
     5581 gatgtataac tatctgttat aatgaaaata tattaaaaat catagtgttg aagaggaaga
     5641 gtagagtaga aaccattctc agagaatttg ggtctatggc tgagagccca tgtaataggt
     5701 ctatttgaaa actaccttgg agctgagctt attagcagta tttgtactat acgtgaaagt
     5761 gctcgggtga cgaccttata gtcatcaaga gggttgtata tacttgtata cgccaacttg
     5821 ggtggaaccg cgaattaata tcgtcccaaa catatttggg gcgatttttt attacaaaaa
     5881 atctaaaaat tatttcaata aggaggaaaa aacaatgatt aaagttgctt taaaagatgg
     5941 ctcaataaaa gaatttgaaa atgctatttc tgttatggat gtagctaaat ccattagtga
     6001 aggattagct agaaatgtgg tagcagcgtc tgtgaacgga gaggttgtag gtctggacca
     6061 cattatagat actgattgtg acttgaattt atttaagttt gaagataaag aaggtaagga
     6121 agtttttaga catacatcag cacatatatt agctcaagct ataaaaagac tttacccaga
     6181 agcaaagctt gctataggac caagtataga aaatggattc tactatgata tagatttaga
     6241 ccatagatta gttccagagg acctagagaa aatagaagct gaaatgaaaa aaatagctaa
     6301 agaagattta aaaatagaaa gatttgaact tcctagaaat gaagctttag agcttatgaa
     6361 agaacaagga gaagactata aggtagaact tatatctgat ttacctgaaa gtgaaataat
     6421 atctttctac aagcaaggtg attttactga tttatgtaga ggaccacatt taccatctac
     6481 taaaaaggta aaagctgtta aattacaaag tgtagcaggt gcatattggc gtggtgacga
     6541 aaataataag atgcttcaaa gaatatatgg aacttctttt gagaaaaaca aagacttaga
     6601 agagtactta catttactag aagaagctaa aaagagagac cacagaaaat taggtaaaga
     6661 attaggatta tttatgatac ctgaagaagg tccaggattc cctatgtttt taccaaaagg
     6721 tatggaactt aaaaatgaat tattaaaatt ctggagagaa atacacagaa aagctggata
     6781 tattgagata gaatctccaa tcatattaaa tagaaaatta tgggagactt caggacactg
     6841 gtatcattac aaagaaaata tgtatacagt taaaatagat gatgaggatt atgctataaa
     6901 acctatgaac tgtcctggtg gattaattta ctataactct caactacatt catatagaga
     6961 tttcccaatg agagttgcag agcttggtag agttcataga catgagttat ctggtgcatt
     7021 acaaggatta atgagagtta gagcatttac tcaagacgat tcacatatat tcatgttacc
     7081 agagcaaatt aaggacgaaa taaaaggagt agctaactta atagatggta tctacaaaac
     7141 ttttggattt gaatataatt tagaattatc tacaagacca gagaactcta tgggaagcga
     7201 cgaagagtgg gaagcagcag aaaatggatt aagagaagct ttagaagagt taggtctacc
     7261 atatactatt aatgagggtg atggagcatt ctatggtcct aagatagact tccatctaaa
     7321 agattgttta ggaagaactt ggcaatgtgg tactatccaa ttagatatgc aacttccaag
     7381 acaatttgat aatacttata ttggtcaaga tggtgaaaag catagaccag ttatgattca
     7441 tagggttgct tttggtagta tagaaagatt tataggtata ttaatagagc attatgctgg
     7501 taaattccca gtttggttat ctccaactca agttaagata cttcctatat ctgataaatt
     7561 tatggattat gcaaatgaag ttaagaaaga gttatttgat aagggtataa gagttgaatt
     7621 agatgataga gctgaaaaaa ttggatttaa gataagagaa gctcagcttg aaaaagtgcc
     7681 atacatgtta atagtaggtg aaaaagaagt agctgataat aatgtttctg ttagatcaag
     7741 agataaaggt gaaataggta gtattaaatt agatgaattt atagctagta tttcaaaaga
     7801 aattgaatca agagaaagta ttattcaaga ctaatatata atatattagt agctaagata
     7861 ttgttatata agataagttt aatcaatatg ttgatatgtt gatacatagt gattaaattt
     7921 atgaaaagat gagtataatt agaggtacag ttaatcatat ttttatgatt aatgtgcctc
     7981 tagttttttg tatggtagat ttattaataa atatatcata gaagtgtttt gaacatggaa
     8041 atatttatgt gcattcttta aataaaagtt tattttttga atgataatta agtgcttgtt
     8101 ggtaaggtta tggctgtaaa aatcataact ttattttcat atttgttcca ttttcataaa
     8161 aattattata cctttaagaa aatttcttaa tcctcttgaa atatttcctt tttagtctaa
     8221 agttaaattt ctttcttcaa aatgaatatt taaatgaact aaaatttaag tacattttct
     8281 aatcttatga gtctattttt catagataat tgccctataa tagattaatg tcatttattt
     8341 tatctgaaaa actttcattt ttagccacta tatagttatc ataattgtat ttaggattaa
     8401 gagtattaaa agggaaatta aaagaatgtg aaattatagt tcctataagg agtgagacaa
     8461 atacaataga aagtgatatt gccaggatac tccagatgaa aatctttgcc tttataagct
     8521 ttttattcat atttatcctc ctccttgtag ccttttagtt gtataattcc tttgacaatg
     8581 ttgataccag caacacctat tataaatagt atccacgaaa aggaccaaat attaaatagt
     8641 atgcttgtga ttagatatat agaaactatt ataatccaat atgcattcat aaatgattta
     8701 taaactggat ttatatgatt ataattttcc tcaaaatcct cagattcttt gaatttattt
     8761 gataaattat cattgtatag agcatagttt gtccttgtca tttgattata gactaataaa
     8821 cctactccaa gtgctattaa tatgagcatt aaaagaatag ctatagttgg ttctatgcca
     8881 aaacttacaa ctgagactac aaataggaaa gggcttatta taaaaagagt aactgctatt
     8941 gatgctctta aggctctttt ctttttttct tcaattaatt cagaaggtag agaatatggt
     9001 tccttaacac tttcaattaa ctcagataaa tcaccaattc ctgagattac tgagttatat
     9061 gcttcttgtt ctgttttacc atcttgtatt tggtcgttat acttttcttt tagattttca
     9121 aataattcat ctttaagttc tttgactttt tttgtctcat taactcctgt aaagctactg
     9181 tcaatataag tacgtatttt gtctaacata ttttcacctc ctaaattaat atatctatca
     9241 atgcttttgt attattccat tcttcacggc tttttatata tttctcttta cctatgcttg
     9301 ttattgaata atactttctt ctagctccag taacttcatc accccaataa gaggttattg
     9361 caccagattg ttcaagtcta cgaaatgctg tatacaaagt agcttctttc aactcataca
     9421 atcctttggt tttttcaagt atagatttat taatctcata accataactg tctttttcaa
     9481 gtaaatgttt taagataatt gtttctgtat gacctcttat catgtcagat gcgattatca
     9541 tgaacatcac ctccaattaa atatataata ctttgatata cttcgcctgt caaggtatat
     9601 catgagaaaa gacattttat tgtaatattt ataagatttt atatagaaat aatgtaaaaa
     9661 ctttataaat aatatatttt atacctagtt atagataact ttatatagtt attattaaaa
     9721 aaagcaataa aaagtttaat tcaatttagc aaatttagtg atataattaa aaaagaaaag
     9781 aaatatggac ttatttggaa taattttgac aatctattta ctacacgtgt agagtcgtat
     9841 ataattaaat tatacataaa atataaaaaa ataatttagt aatacgttag gagaaagtat
     9901 tatgataaag tcaagcttat tttggaatat tttcattgcg atatccttta tgatagaatg
     9961 gtttctttgt aagaaaatgc tagattatac aagtgagaaa aggatttcta acaaaaaaat
    10021 aaacttttgt atggtaggta ttattgtttt tgctgacata atatattttt ttgatgtacc
    10081 tccaaatata agagtaatta tatctatgat aattactatt gcattttata aaatctcata
    10141 tgatgtggga tttataaagt ctgtattaat atccttaatt tattggatgt tactaatcgc
    10201 cacagatgct ttgagtatat ctttaacagt ttggcttaat tctataaatg acatgagtag
    10261 tatggggacg ggagatatat acagaattga gtctataata ttgggaaaga tacttttgat
    10321 tgtgtctttg tttttatata gagccttaaa gataaaactt aatatagaaa taaataaaag
    10381 gacattattt tatatagtta ttcctatagt cgctaatata gcatcttttt ttgtaatttt
    10441 tgaatacata tttaatccag ggtctggtag cttaatacat aatttccaat tcgttatgat
    10501 ttctgttgta ttgcttatat caagtatcac tttagtttta attgctaaaa aattacagca
    10561 atataatact ttagttgtag aaaacaatat gattaaaaat actttgaagt atgaaaatga
    10621 gtattatgaa gatatagaaa agaaatattt aaaaactaga ttactaagtc atgatatgaa
    10681 aaatcacata ctgtgtataa atgctatgat taaaaaaggt attgatgtta cttcttattt
    10741 aaataatttg caggtagaaa ttcagagtaa tgacttgtta tttaatactg gtaattttat
    10801 attagatgct atattaagtg aaaagaaaga ggtttgtgat aagaatgata tagaactaaa
    10861 aataggaata aattttagtt gttgtgaagc tgttgaatta gtggatatat gtcatatatt
    10921 ttcaaatatt ttagacaatg caattgaggc atgtaataaa attgatagtg gaaatagagt
    10981 tatttgtgtt aaaggtgatg ttatgcaaaa tttttattta ataagagttg aaaatactaa
    11041 gataaataag attattacta aaaatggaga tattttgaca gacaaaaaag gttctcttca
    11101 tggacttgga ataaaaagtg taaaaaactc tgtaaataag tatggtggta atgttgtaat
    11161 tgaatatgat gataaaaaat ttgtagttaa aattgctatt ccacttagaa atgtgaagaa
    11221 agcagttaat catgtgattt aaatgtatat aaatttgatg tgtagaagtt taatatataa
    11281 gaattaatgt ataaaagtga tgtataggag tttaatatat aagaattaat gtataaaagt
    11341 gatgtataga agtttaatat ataagaatta atgtataaaa gtgatgtata gaagtttaat
    11401 atataggaat taatgtataa aagtgatgta tagaagttta atatataaga attaatgtat
    11461 aaaagtgatg cataaaagtt taatatatag gaatttaata tgtataaaag tgatgcatag
    11521 aaatttaata tataagaatt taatatgtat aaatgtggtg catagaagtt taatgtaaaa
    11581 atttggtgta
//
LOCUS       DACTZW010000112        11332 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.113, whole genome shotgun sequence.
ACCESSION   DACTZW010000112 DACTZW010000000
VERSION     DACTZW010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11332)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11332)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11332
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.113"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(94..519)
                     /locus_tag="JAM15_16975"
                     /pseudo
     CDS             complement(94..519)
                     /locus_tag="JAM15_16975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902013.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(992..1279)
                     /locus_tag="JAM15_16980"
     CDS             complement(992..1279)
                     /locus_tag="JAM15_16980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799943.1"
                     /translation="MRLNVTKQNTIEVENSRKEDVYFVIVDNVFFERQGDVFNSITNN
                     NLNNYDVKILPTDNVFLELKITSTKDLEPVFIVVEDRQYNHGSIMFKPVLV"
     gene            complement(1299..1574)
                     /locus_tag="JAM15_16985"
     CDS             complement(1299..1574)
                     /locus_tag="JAM15_16985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799944.1"
                     /translation="MSLFVGGWSKFRAVEEEDLKVFNEAVGMIKGVDYEPLIVATQVV
                     AGTNFKFICNATSVTNPPHDYLAEIIVFKPLPCDEHNATITSINIIK"
     gene            1762..2581
                     /locus_tag="JAM15_16990"
                     /pseudo
     CDS             1762..2581
                     /locus_tag="JAM15_16990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418025.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
     gene            complement(2840..5407)
                     /locus_tag="JAM15_16995"
     CDS             complement(2840..5407)
                     /locus_tag="JAM15_16995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002602373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HAT6799945.1"
                     /translation="MIYYVLPLEHKQATIEIVGGKGMSLSKLLTAGIPVPDGFHVTTA
                     SYQIFVETNHIQSRINKLLDGIDSNNTSQLEDVSKKIGELFHNGEMPQEVSDAIKTAY
                     AGLGNISVAVRSSATAEDLPDASFAGQQETYLNIQGEDKVIDAVKRCWASLWTARAIA
                     YRVKNNIKHEIVALAVVVQKLAFSDSSGIMFTLNPINGRRSEMIINAAWGLGEAVVSS
                     LVTPDTIVVDKDSERIISYEVANKEIMTVRTSEGTEETMVPKRLRKKYALTRNQVMQL
                     IQLGKKIEKYYQMPMDVEWALEKDKLYIVQARPITVLPPEWVLPEQDVVYTKGSLAEH
                     LPNPVTPLFATLGLEIVNRASELLWIDMFGKSAKKLLPKNGAYTVINGYVYLSAKSKP
                     LLIAIKSLSPRSLRRTLMNSVARWETARKGYEDAIKQWEEKPLHTMNAHQIMDGIQTI
                     FYAACIYFTRIQLTLPAASISETLFTKLFQGAVRRAGITDTSVFLLGFDTIALQSEKE
                     LWGLSEWVKQNNSINLYLQNSPAIKIAEDFMSSVMPVGVSQEVWIEWKNRINKYFKEF
                     GRTAYEFDFAYSTPQETLTPTFESVKTFVEGKGESPFLRQTTFEKRRKHAEEEILQHI
                     SGLRKKLFFKLLHWAQETSPMRENAIYLMGMGHPLIRCMFQEISERFIRGGAISHLDD
                     IYWLTKSELEVLIEQLDKNKSLSDMNGIIPVRKAELKKYMGYVSPSKLPEKNKKTISQ
                     APQKQKDGKIVLTGIGTSTGVVTAPACVLNSPADFESFQPGSVLVAVTTTPAWTPLFS
                     SASAIVTDIGGPLSHSSIVAREYGIPAVMATHIATRTIKSGQMITVDGLAGTVTFDE"
     gene            complement(5410..6015)
                     /locus_tag="JAM15_17000"
     CDS             complement(5410..6015)
                     /locus_tag="JAM15_17000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002591427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAT6799946.1"
                     /translation="MPKGIVLTPEQQAERREKIVAVALSLMAENGFQKTSMREIAVLA
                     NMGKSSLYDFFKTKDEIVVYAVEKEIEKTIQQVHRIIDGEPSPQQCLRKIMLNHLRFP
                     EQYRTVLMWLNTESDYLEEEYRKRLKDARYAYQDIIKSIIDNGVTTGIFRKTDTALVT
                     RLLINSMLSISYTSRPSDSSEKMLDETMNIFLHGIMNDGGE"
     gene            complement(6401..7861)
                     /locus_tag="JAM15_17005"
     CDS             complement(6401..7861)
                     /locus_tag="JAM15_17005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HAT6799947.1"
                     /translation="MFNELKTKENVYKNLINGKWVESNSRKPIEIYSPIDNSLVGKVQ
                     SMTKHEVDEVIKNTKESIKVWAEMPVYKRANIFHKAADLLLENIDEIANILVLEIAKD
                     IKSARAEVERTADFLRYTADVGKNMEGEAISGDNFPGGTRNKMSYVSRVPLGTVLAIS
                     PFNYPVNLSMSKIAPALIGGNAVVLKPATQGAISALHVVEIMRKAGIPDGVLNTITGR
                     GSEIGDYVVTHKGINFINFTGSTEVGQHISKISGMVPLLLELGGKDAAIVLEDADLDF
                     AAKNIVSGAYSYSGQRCTAVKRILVQESVADKLVGKIKPLVEKLTIGNPMDEVVITPL
                     IDNKATDFVQGLVDDALHKGAKLITGNVRKNNLFYPTLLDNVNVDMKIAWEEPFGPVL
                     PIIRVKDINQAIEIANQSEYGLQSSVFTSDIDRAFYIADKLEVGTVQINNKTERGPDH
                     FPFLGVKASGMGTQGVKYSIEAMTRPKAVVVNVREL"
     gene            8248..8826
                     /locus_tag="JAM15_17010"
     CDS             8248..8826
                     /locus_tag="JAM15_17010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAT6799948.1"
                     /translation="MAKSFTEIEKDNIRKRLISECEINWSKYGYKKTNIDELCSKSGI
                     AKGSFYTFFDSKEKLFFEVLNGIQNRLISSVDEILSNMPPKEGFAKSLKMLYRLYDKN
                     PFLYSPNNPDFISLINKLPQDMFLQLESNNIQSFYDLIERHNLKLKIEKEKAFGVCNS
                     LLSSLLVKENIEYNYIEVFDFMVDNLVEHILE"
     gene            9118..10368
                     /locus_tag="JAM15_17015"
     CDS             9118..10368
                     /locus_tag="JAM15_17015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAT6799949.1"
                     /translation="MVKSSNTFNKNFNLMILGQIISLFGASILKFALSLYILDITGKA
                     EIFATILAVSSIPIIVFSPIGGAIADIFNRRNLMVIFDFSSSLTVLILAVFLFNNNGS
                     ILLVGIIMTILSVISTMYQPTVQSSTPLLVDNEHLMNANGIVAGVASLTNIAGPVLGG
                     VLYGVIGINAIIVISCVSFFLSAIMEIFIQIPFIKQEQNSNIIKTIFTDIKDGIVHIC
                     KENRFILKILFLAIAINLFLSSMLIVGIPYIVKITMGASNFLYGLAEGAISFSSLVAA
                     VSIGIFSKHLKITNLHISFIICAVMFIPMAVSVYPFILNTGFPVPFLIFIVSSMLIFF
                     TTTLISIYVITVTQLKTPNELLGKVMSILFAGTAIAMPLGQVMYGKLFDLLSDRVYII
                     ILGVGFITLLIAFVSKITLRNENL"
     gene            10529..11098
                     /locus_tag="JAM15_17020"
     CDS             10529..11098
                     /locus_tag="JAM15_17020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HAT6799950.1"
                     /translation="MSYMPTLEQAWEILRKYNKEEFHIRHAQIVSGVMRYYAKEYDPE
                     RVDFWEIVGLLHDLDFEMYPDEHCVKQRELMTELDLDKSIIDSTISHGYGLTGSDVKP
                     EQFMEKVLFAVDELTGLIGAAAIMRPSKSVSDLELKSVKKKFKDKSFAAGCSRDVIRS
                     GAEMLGWELDKLIQTTIEAMRSLIPEMAI"
BASE COUNT         3744 a         1978 c         1582 g         4028 t
ORIGIN      
        1 tctatcctat ctctacatat aggtttccct atatgctgac tattttagct actaactcat
       61 gactaaagtc acgagtgtgc gtagctattt tttaatcaat acaattactg cacatataga
      121 tgcagaattt ttaaatactt cacctaatga aactgctgca ctaatatcat gggctactcc
      181 cctattgtcg ctaaaacctg cagtatcaca taattttgca tccattcctt ctattggttt
      241 tctcatattt acaatgttcg ggtataaagt ttgagaaaca gctcctgaac caatctctgc
      301 cacagggtct aagcaatcaa tatatgatat accagtatct tcatcttcta cttccatcat
      361 tacacatcct gcaagatagt taattgcagt acttttgcca catcctgtcc caccaagaat
      421 tagaattaaa ttttgatttt cagccttatt tattgctact tttccttcat ttaataagag
      481 tgttatttct tctaaaagtt gattgttatt ttctggcatt tattttcccc cttggttata
      541 tattttattt aaataaagtt taatccctta agtagattac aaagttttta gactatattt
      601 aaatttgttt tttattttta ataaatttgc attttcactc aataattatt cttctttgtt
      661 tattaaaata actgtgttgt ataatataat ttttaccaac acagttattt tatttaatgc
      721 gcttatttta ttgtatttta tgtaatacag ttgttttttt atattatatg tccactattt
      781 tcctatggtt attacatata gatttttaat tatatttgta ccattaattt aaacattcct
      841 atactactgc ttaagtttta cacctatacc agcttgaata ttttattttt atttgcttaa
      901 atagttcaac tatactggtt taataggttt cctttagttt aaatagttca cctataccta
      961 cttgaatagt tcacttttat ttgcttaaat tctataccaa tactggctta aacattatac
     1021 taccatgatt gtattgtcta tcttcaacta caataaaaac aggttctaaa tctttagtag
     1081 atgttatttt taattctaaa aaaacattat cagttggtaa tatttttaca tcataattat
     1141 ttaaattatt attcgtgata ctattaaata catcaccttg acgttcaaaa aaaacattat
     1201 caactattac aaaataaaca tcttcttttc tactattttc aacctctata gtattttgtt
     1261 tagttacatt tagtctcatc ttccacctcc tattaatatt acttaattat attaatactt
     1321 gtaattgttg cattatgttc atcacaagga agaggtttaa aaacaattat ctctgctaaa
     1381 taatcatgtg gaggatttgt aactgaagta gcattgcaaa taaatttaaa atttgttcct
     1441 gctacaactt gagtagcaac aataagtggt tcataatcaa ccccttttat cattcctaca
     1501 gcttcattaa atacttttaa atcttcttct tcgacagccc taaattttga ccatccacca
     1561 acaaaaagac tcatataaaa acctcctata tatatatatt tatttatata atagtaccaa
     1621 ttttcttaat attcaatata ttgcgtgtaa ctggtcaata aaaatgcata actggataaa
     1681 aagacttata aaatagctta actttacata ttataagatt gttctaaaat atgagacaca
     1741 tcttgctttg aatatattct atacaacaat tttccaggcc tcattgccaa atttaaggta
     1801 actgacttta gattccaact tcttgatgct aataaaaaat attttgatat gttcaaagat
     1861 aatgtaaatt ttctattaga tgatataaat ttagaaggtt atcttaacaa tgtgtataaa
     1921 tatcataatg attttaaagc tgggagatgc gtttgttttt ctatttctcc acaaactatt
     1981 aatggagata tttttcacat gcaagttgta gctgaatgta tagattggga agatgataag
     2041 cctatatatc ttttaatata ttcagatgta acgacattgg taaaacaata tgtctcatta
     2101 tcatttttca tccaagaatt ttatcaagaa atatgataaa atagctaaaa aatatgatat
     2161 tccttctcac cttatagaaa ttgagattac agaaacaatt gtatttgaag atgtcaaagt
     2221 atttagtgaa ataataaatg aaattcataa aaatgacttt aaatgctcta ttgatgattt
     2281 tggaagtggc tattcttcaa tcaatatgct taagggtatt tatgttgata cattaaaatt
     2341 aaatagagca ttttttcaat cagaagattt agattctcaa cgtgaaagaa atataattgt
     2401 atctataatc gaactagcta aaaagttaaa aatgaccact gtagctgaga gaatagagac
     2461 cagttttcaa aaagatttct tgcaagaaat aaactgtgat atgttacaag gatacgtgtt
     2521 ctctagacct ttgcaaataa aagactttga aaaacttatg tttcaaaact cctccaatta
     2581 acagtataaa attgcttatt ataagtgtat tattgtatca acaaataaag gaattgtctc
     2641 aaaattgatt ttttctaatc aaatttttat tttgagacat tctcattttt ttgcataaga
     2701 aaatacccac caagctacgg tttttcttac cgctgttcgg tgggtattag tagtattatg
     2761 aaatctgaaa actttaagta ttactacttc cgctaacgca atcacaaagg tcgaaagctt
     2821 caaagcgaaa ataggctttt tactcatcaa acgtcaccgt acctgccaac ccgtccaccg
     2881 ttatcatttg tccgctctta atagttcgtg tggcaatgtg tgtagccata acggctggga
     2941 tgccatattc acgtgcgaca atgcttgaat ggctaagagg accaccaatg tccgttacaa
     3001 tcgcacttgc agatgaaaat aatggtgtcc atgctggagt tgtggtaact gcaaccaaaa
     3061 cacttccagg ttgaaagctt tcaaaatctg ctggactatt cagtacacaa gctggagccg
     3121 tcacaacacc agtactggta ccaatgcccg tcaacacaat tttcccatct ttctgcttct
     3181 gtggtgcttg tgatatagtt tttttgtttt tctctggcaa cttggacggt gacacataac
     3241 ccatgtattt tttaagttca gcttttcgaa caggtattat cccgttcata tcagatagag
     3301 acttgttttt atccaactgc tctataagta cctccaattc cgattttgtg agccaataaa
     3361 tatcatctaa atgtgaaata gctcctcctc gtatgaatcg ttctgagatt tcctgaaaca
     3421 tacaacgaat cagaggatgt cccattccca tcaaataaat agcattttca cgcataggag
     3481 aggtttcctg tgcccaatgg agcaacttaa aaaatagttt tttacgcaat ccacttatgt
     3541 gttgtaaaat ctcttcttct gcatgttttc tacgcttttc aaacgtggtc tggcgtaaaa
     3601 aaggactttc cccttttcct tccacaaatg tttttacgga ttcaaaagtt ggtgtaagtg
     3661 tttcctgcgg tgtggaatac gcaaaatcaa actcataagc ggtacgacca aactctttaa
     3721 agtacttatt gattcgattt ttccattcta tccatacttc ctgtgaaact ccaacaggca
     3781 taactgaaga catgaaatct tctgctatct ttattgcagg actgttttgc agataaaggt
     3841 tgatgctgtt attttgcttt acccattctg aaagacccca caactccttt tccgattgca
     3901 gagcaatcgt atcaaaccca agcaggaaaa cggaagtatc cgttatacca gcacgtcgaa
     3961 ctgctccttg aaataatttt gtaaataatg tttcactgat agaagcagca ggcaatgtaa
     4021 gctgaatcct tgtgaaataa atacatgcgg cataaaatat tgtctgaata ccatccataa
     4081 tttgatgggc gttcatcgta tgcaggggct tttcttccca ttgtttaata gcatcctcat
     4141 atccttttcg tgccgtttcc cagcgtgcaa cgctgttcat aagtgtccta cgtaaagagc
     4201 gtggggaaag ggatttgata gcaatcaaaa gtggctttga tttagcagaa agataaacat
     4261 atccattaat aaccgtatat gcgccgtttt ttggtaataa ttttttcgca cttttaccaa
     4321 acatatctat ccataaaagc tccgatgcac ggtttacgat ttcaagacca agcgtggcga
     4381 acaaaggtgt aacaggattt ggcaagtgtt ctgccaaact tccctttgtg tatacaacat
     4441 cctgttctgg caatacccat tccggtggca gaacagtaat tggacgagct tgaacaatgt
     4501 acaatttatc tttttccagt gcccactcta catccatagg catttgataa tacttctcaa
     4561 ttttctttcc aagctgtatc agttgcatta cctgattacg agtaagagca tatttttttc
     4621 tcaacctttt aggaaccatg gtttcttctg ttccttctga agtacgaacc gtcataatct
     4681 ctttatttgc cacttcatac gatataattc gttcggaatc cttatccact acgattgtat
     4741 cgggtgtaac taagctagaa accaccgctt caccaagccc ccatgcagcg ttaataatca
     4801 tttcgctacg tctaccattg attgggttta acgtaaacat aataccagat gaatcagaaa
     4861 atgcaagctt ttgtactaca acagcaagtg cgacaatctc gtgctttata ttattcttca
     4921 cacgataagc aatagcacga gctgtccata aggaagccca gcatctcttt acagcgtcaa
     4981 taactttatc ttcaccttgt atgttaagat aagtttcctg ctgacctgca aaagaagcgt
     5041 caggtaaatc ttcagcagtc gcagacgaac ggacagccac cgatatgttc cctaatccgg
     5101 cataagctgt tttaattgcg tccgacactt cctgtggcat ttctccatta tggaaaagct
     5161 cccctatttt cttagataca tcttcaagtt ggctggtatt attggaatca ataccatcta
     5221 gcagtttatt aattcgagac tgaatatggt tcgtctcaac aaagatctgg tatgaagcag
     5281 tcgtaacatg aaaaccgtct ggcacaggga tgcctgctgt caatagtttt gataaagaca
     5341 tcccttttcc accaacaatt tcaatggttg cttgtttatg ttccagtggc aagacataat
     5401 aaatcataat cattcacctc catcattcat aattccgtgc agaaatatat tcattgtttc
     5461 atccaacatt ttttccgaac tatccgatgg tcgtgacgtg tagctgattg ataacatgga
     5521 gttaattaac aaacgtgtca caagagcggt atccgttttg cgaaagatgc ctgtggtcac
     5581 accattatca attatcgatt ttataatatc ttgatatgca taacgagcat ctttaagtct
     5641 ctttcgatac tcttcttcta aataatcaga ttctgtattt aaccacatca gtacagttct
     5701 atactgctct ggaaatctaa gatgattaag catgattttt ctaaggcact gttgtggtga
     5761 aggttcacca tcaataatcc tatgaacttg ttggatagtt ttttctattt ctttctcaac
     5821 tgcatataca acaatctcgt ctttcgtttt gaaaaaatcg tatagacttg actttcccat
     5881 gttggctaaa actgcaattt ctctcattga tgttttttgg aatccatttt cagccatgag
     5941 actcaaagca acagcaacta ttttttctcg gcgttctgct tgttgttcag gtgtaagcac
     6001 aattcctttt ggcatagggc gatacctcct tttagcgacc aatggtcgtt tcttttttat
     6061 ttatcataca gcgaccatcg gtcacttgtc aaggttaatt tttttcattg tatatggtac
     6121 tcgagataaa aatgttcatt ttagaaattg ctctatttaa gtagaaatag gcttcatcat
     6181 tagaaaacaa gaccataaat ttgagatatt tatcatgttc aaatttcatc aatatcaaag
     6241 tttaaaatat taataaaaaa agaattacta agaaataaca tataaagatt caaaaaagga
     6301 gttgaactta aaattcaatt acaaaaaatc aaatttaaga caactccttt attttttatt
     6361 tctattattc tttatctcta ctattcttta tctctattta ttacaattct ctaacattta
     6421 ccactactgc cttaggtcta gtcatagcct cgattgaata cttaacacct tgagttccca
     6481 taccagatgc ctttacacct aaaaatggga agtggtctgg acctctttca gtcttattat
     6541 ttatttgaac agtaccaact tcaagtttat cagctatata aaatgcccta tcaatatcac
     6601 ttgtaaatac tgatgattga agcccatact ctgattgatt agcaatttca attgcttgat
     6661 ttatatcttt aactcttata attggaagta ctggaccaaa tggttcttcc caagcaattt
     6721 tcatatcaac atttacatta tctaacaatg ttggatagaa taaattattt tttctaacat
     6781 tgcctgttat taactttgct cctttatgta atgcatcatc aactaaccct tgaacaaaat
     6841 cagttgcttt attatctata agaggagtga taactacttc atccattgga tttccaattg
     6901 tcaacttctc taccaatggc tttatttttc cgactaattt atccgccaca ctctcttgta
     6961 ctaaaattct ctttactgcc gtacatcttt gtcctgaata tgaatacgct ccagatacta
     7021 tattcttagc tgcaaaatct aagtctgcat cttctaatac tatagccgca tcttttccac
     7081 caagctccaa taatagtggt accattccag atattttaga tatatgctga ccaacttcag
     7141 tactaccagt aaagttaata aaattaattc ctttatgcgt tacaacataa tcccctatct
     7201 cactacccct acctgtaata gtattaagta ctccatctgg tatcccagct tttctcataa
     7261 tttctaccac atgaagtgcg ctaatagccc cttgtgtagc aggttttaat acaactgcat
     7321 ttccaccaat aagcgctgga gcaatctttg acattgataa atttacagga taattaaaag
     7381 gagatatagc taaaacagta cctaatggaa cccttgaaac ataagacatc ttatttcttg
     7441 ttccaccagg gaaattatct ccactaatgg cttcaccctc catatttttt cccacatcag
     7501 ctgtgtatct taaaaaatct gctgttctct caacttctgc ccttgcagat tttatgtctt
     7561 tggctatttc aagtaccagt atattagcta tctcatctat attttctaac aataaatcag
     7621 cagccttatg aaatatattg gctctcttgt atacaggcat ttcagcccat acttttatac
     7681 tctcttttgt gttttttata acctcatcta cctcatgttt tgtcatagat tgtactttcc
     7741 caacaagaga attatctatt ggtgagtaaa tttctattgg ctttctcgaa ttagattcta
     7801 cccattttcc atttattaaa tttttatata cattttcttt tgttttaagt tcattaaaca
     7861 tatttttatt cctctctctg atataacttt gtgtatttaa attatagcca tttattcgtt
     7921 atgtaaacat ttcttttttt cataaacgtt tacctataaa aaaaatttta agttaacgtt
     7981 tttctagatt cttctatttt aataacatac tcgctccaaa tctatatagg tcacacttta
     8041 atatcaatat accaatatac caatatacca atataccaat ataccaatat accaatatac
     8101 caatatacca atataccaat ataccaatat aaatattata aacataaatc acttgacaaa
     8161 tttataagta gacaatatta tatatctatg acttaaaata tttttaaagt catagatatc
     8221 atatacagat agaaaggatt gataaaaatg gctaaaagtt ttacagaaat agaaaaagac
     8281 aatataagaa aaagactaat ttcagaatgt gaaatcaact ggtctaaata tggatacaaa
     8341 aaaactaaca ttgatgaact ttgttcaaaa tcaggaatcg caaagggttc tttctataca
     8401 ttttttgatt caaaagaaaa gttatttttt gaagtactaa atggaatcca aaacagactt
     8461 atatcatcag tagatgaaat tttaagtaac atgcctccaa aagaaggctt tgcaaaatcc
     8521 ttaaaaatgt tatatcgatt atatgataaa aatccatttt tatattcacc aaataatcct
     8581 gatttcatca gcctaataaa taaactacct caagatatgt ttttacaact tgagtccaat
     8641 aacatacaaa gtttttacga cttaattgag agacacaatc tcaagttgaa gatagaaaaa
     8701 gaaaaagcct ttggtgtttg taattctcta ctatcaagtc tattggtaaa agaaaatatt
     8761 gaatataact atattgaagt atttgatttt atggtagata atcttgtaga acacatactt
     8821 gaataacaat ttaaaataat ttttctaaat atttctttat actaaagagg attaatatga
     8881 ttgaattaat gaaaaaaata aacaatatca tttacaaaat aaatgataaa ctaaatatac
     8941 acacaaaact tatagacccc agagttaact cattccactc tactctaagc catctataat
     9001 agttcgtata tttctaataa tattagatat taaagtaaga aaaaaattcc ttataataat
     9061 tgctattata tcaattatta taaatatttt aataatctta gataggtagg tatatatatg
     9121 gtaaaatcct caaacacttt taataaaaac ttcaacttga tgatattagg tcaaataatc
     9181 tcattgtttg gtgcatcaat acttaaattt gctttatctt tatacatact tgatataact
     9241 ggtaaagcag aaatatttgc tactatacta gcagtatctt caatcccaat tatagtattc
     9301 tcccctattg gtggagctat tgcggatata ttcaacagaa gaaacttaat ggttattttt
     9361 gatttttcaa gcagtcttac agtactaatc ttagcagtat tcttattcaa caataatggt
     9421 tcaatattac ttgtaggaat tattatgacc atattatcag ttataagcac aatgtatcaa
     9481 ccaactgttc agtcaagtac acctctttta gttgataatg agcatttaat gaatgcaaat
     9541 ggtattgtag ctggagttgc atctcttaca aatattgcag gacctgtatt aggaggtgtc
     9601 ttgtatggtg tgattggaat taatgcaatt atagttataa gttgtgtaag tttctttcta
     9661 tctgcaatta tggagatatt tatacagatt ccttttatca aacaagagca aaacagcaac
     9721 attataaaaa ctatatttac tgatataaag gatggtattg ttcatatatg taaagaaaat
     9781 agatttatac taaaaatact ttttttagct atagcaataa acttattttt aagctctatg
     9841 ttaatagttg gtatccccta tatagtaaaa atcactatgg gagctagtaa cttcttatat
     9901 ggtctagcag aaggagcaat ttcttttagt tcactggtag ctgctgttag tattggtatt
     9961 ttctcaaaac atctaaaaat cactaatttg cacatttcct ttattatatg tgcagttatg
    10021 ttcataccaa tggcggtttc agtatatcca tttatattaa acacaggatt tccagttcca
    10081 tttttaatct ttatagtatc atctatgcta atatttttta caacgactct tatctcaata
    10141 tatgttataa cagtcacaca attaaaaact ccaaatgaac tcttaggaaa agtaatgtca
    10201 attctttttg caggaacagc aattgcaatg ccccttggtc aggttatgta tggtaaactt
    10261 tttgatttat tatcagatag agtgtacatc attatactag gagttggatt tattacacta
    10321 cttatagcat ttgtgtcaaa gataacattg aggaacgaaa atctttagat acaaagaatt
    10381 tagatataaa gatttaattt tcactaattt ctgaatttaa atgcaaaatt gcgtatcagt
    10441 atgttgacgt tttagaaatt gattgatata atcaatggaa aataaacttt ataaaaattc
    10501 aaaatattca gctagaggag tgataaaaat gagttacatg ccaactttag aacaagcatg
    10561 ggaaatatta agaaaataca ataaggaaga atttcatata agacatgctc aaattgtatc
    10621 tggagttatg agatactatg caaaggagta cgaccctgag agagtagact tttgggaaat
    10681 agttggactt ttacatgatt tagattttga aatgtatcct gatgaacatt gtgttaaaca
    10741 aagagaatta atgacagagc ttgatttaga taaatcaata atcgattcta caataagtca
    10801 tggatatgga ttaactggtt cagatgttaa accagagcaa tttatggaga aagtattatt
    10861 tgctgtggat gaacttactg gtttaattgg tgctgctgca ataatgcgtc cttcaaagag
    10921 cgtttctgat ttagaattaa aatctgttaa gaagaaattt aaagataaat catttgctgc
    10981 tggctgttct cgagacgtta taagaagtgg tgcagaaatg cttggatggg aacttgataa
    11041 gcttatccaa acaactatag aagctatgag aagcttgatt ccagagatgg caatataact
    11101 cctcatacat ataccataga agttacatct ttaaagagca tttctctttt tgatgcaact
    11161 tctttttata ttttgtagaa taaaaagttt aatattttaa actcactata taatctataa
    11221 taaatactat aaataatata atgtataata gtcataaact ttctaacctt aaaagtttct
    11281 aatactcaat aaacaattct aatatacaaa tggcattata tgatttaatt at
//
LOCUS       DACTZW010000113        10758 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.114, whole genome shotgun sequence.
ACCESSION   DACTZW010000113 DACTZW010000000
VERSION     DACTZW010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10758
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.114"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            166..1317
                     /locus_tag="JAM15_17025"
     CDS             166..1317
                     /locus_tag="JAM15_17025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAT6799951.1"
                     /translation="MEIYLDNSATTKPYQEVIDKMVYALNTEYGNPSSVHRKGVEVEK
                     AIKEVRQDIAKSLGAKEKEIYFTSGGTECNNTIIRGITSLNKKRKNHIISTNIEHPSV
                     LNTLKDLEEDGFEVTYLEVGKDGKINIEDLKNAIKSTTCLVSMMHVNNEIGTIQPIGE
                     VGKYLKGLKEKIYFHVDAIQSYGKINFRPSKYNIDFMSVSAHKFHGPKGIGFMYIKEN
                     NRLKPMLTGGGQEIGIRSGTENVPGIYGLGEAVRILNKDLDVVISKVNNLKNILKNEI
                     IDNIEDIKINSPEDGVCHILNVSFRGTKGEVLLHYLEQKGIYVSTGSACSSKKKGSYV
                     LNAIGLTNEEINGTIRFSLSDMNTEEEMLEAVKVLKESICDLRSIMKRK"
     gene            1366..2538
                     /gene="thiI"
                     /locus_tag="JAM15_17030"
     CDS             1366..2538
                     /gene="thiI"
                     /locus_tag="JAM15_17030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HAT6799952.1"
                     /translation="MYNILIVKYGEIGVKGKNRYIFENRLIRNIRNMLKPIGRFNVYK
                     EYGRIYVDLEDYDYEEVIEEVRKVFGIVGVCPGVRAKKDYDTLKEIALKMLEEKIEAG
                     YKTFKVESRRGDKSFGLTSQEMSMDIGGYLLSKVGDRINVDVRNPEVKIKCEYREFHT
                     MVYSDTIPGYGGLPLGTNGRAMSLLSGGIDSPVATWMVAKRGMEVEAVHFHSYPFTSE
                     RSQEKVKDLAKILAKYCGRVRLHKVNILEIQKAIGENCNEEEATILSRRFMMRIAQRL
                     SEKRHCDALITGESIGQVASQTIQGLTCTNAVVDLPVFRPLIAMDKSDIVDIAKKIGT
                     FETSIVPEEDCCSVFSPRKPVTKPRLEKIEKSETALDIEKLVQDAIDKIEVEDIEF"
     gene            2694..3497
                     /locus_tag="JAM15_17035"
     CDS             2694..3497
                     /locus_tag="JAM15_17035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HAT6799953.1"
                     /translation="MNKKGFTLIELLVVISIIGILVIVAVPALFRNIEKSKAVTCLSN
                     RENIKTQIVIAMAEESSKDKNEVIKEVLENKDGKYFETEPKCKSGGIYSATFDDGYDG
                     ITGIESIAKVYVTCTKHPDGIEMARDIHQSMKDLIASFAQDPSIIPGASKGNDDFRKY
                     LLDNKYKNGWPTIPDEFKAKYGLSKDTLYIQPYAYNPTKSDATVVVFANNKTGGNWYT
                     SLVYDYDEGRWYKGKNGISVAGRSWDVDTDSVKSVKTEIHSKEGWGPLN"
     gene            3740..4381
                     /locus_tag="JAM15_17040"
     CDS             3740..4381
                     /locus_tag="JAM15_17040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAT6799954.1"
                     /translation="MNNNFQDNQTINLIQSRRSIRKFTTEQISDEQVNTLLHCAFAAP
                     SGCNKQPWHITVVQDQKLLKEISDDTLSRIHEVSNVEINKNFKLFYGAPTVLFISYDE
                     SSSWAPYDIGILTGNITTAAQALGLGSCIIGMVRGLFTPVEQGDIEGLVSVLDKEDVK
                     ESESIKMKFDTNKKYRELLDIPEGYSVPFGIAVGIPDGNLPNAREVVYKVSRV"
     gene            5795..7465
                     /locus_tag="JAM15_17045"
     CDS             5795..7465
                     /locus_tag="JAM15_17045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HAT6799955.1"
                     /translation="MREESNSLSLDHIEIFFELLSQSTEDYIFFWDINRNKFKISSAI
                     FDEFNLSKEIESDLVNCWSKIVYPDDVQIWKDDIQELLHGKKGEHNLEYRLINKYKEI
                     VWISCRGKVYVADDPKTIFLVGRIKNIGEKNKFDSITGTWNREQFEHRMNYLIKEKIY
                     KNGAMFIMDIDNFKNINEKYGHSYGDKVLRAIATEVLEYLPKDVRLYRLDGDEFAFFY
                     PMCTKETIEKIYEKIQMYTNTQHEIESNKYYCTVTAGVAMYPEDGDNYLDLFKHADIA
                     LDIAKISGKNRIKFFSQELYENKLKVISMQQKLRECVENNFNDFKLFFQPQVNAVTKE
                     VIGAEVLLRWHSSTYGEVSPVEFIPILEQSNLIIPVGKWIIKEAVKQCKEWHKINPDF
                     KISVNVSYIQLKEDFFRDFIVECLVEYQLRPEFLILELTENCWIPDINLLNDKFISLK
                     GIGVYIAIDDFGTGYSSLNYLKELSVNIIKIERSFVKNITYNSYEYTFLEYIIKLAHI
                     INLKVCVEGIESYEEYDIVKSLGVDIIQGFLFGRPVSASEFYKFQLSK"
     gene            complement(7587..8321)
                     /gene="pflA"
                     /locus_tag="JAM15_17050"
     CDS             complement(7587..8321)
                     /gene="pflA"
                     /locus_tag="JAM15_17050"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HAT6799956.1"
                     /translation="MINGKIHSIETFGTVDGPGIRYILFFQGCPLRCKYCHNRDTWDI
                     KSGKEYTVDEIITDALKYTSFMKFSGGGITASGGESTLQPEFLSELFKKAKENDIHTC
                     LDTSGFVDIETIDPVLDNTDLVLLDLKHMVEEKSIDLTGVGMDKALKLARHLESRNIP
                     VWIRHVLVPGITDDIDNLEKLGQFVATLKNVERFELLPYHSMGIHKWESLGIDYELKD
                     VPDATKEDVQKASEIISKFGVKVYNS"
     gene            complement(8481..10712)
                     /gene="pflB"
                     /locus_tag="JAM15_17055"
     CDS             complement(8481..10712)
                     /gene="pflB"
                     /locus_tag="JAM15_17055"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HAT6799957.1"
                     /translation="MNAWQGFKTGRWTKEINVREFIQLNYSPYEGNDSFLAGATENTK
                     KLWDEAMVLFKKERENGGTLDVDTKTVSGIAAYAPGYLDKELETIVGLQTDAPLKRAV
                     MPYGGIKMVENSCEAFGYELDPEIKDIFTKYRKTHNQGVFDVYTPEMRAARKSGIITG
                     LPDAYGRGRIIGDYRRVALYGVDALIEDKNEQKKSLEVSCMDEEVIRLREEITEQISA
                     LNELKKMAESYGFDISKPATNSKEAVQWLYFGYLGAVKDQNGAAMSLGRTSTFLDIYF
                     ERDLKAGIVTEEELQEYMDHFVMKLRMVKFLRTPDYNNLFSGDPTWVTECIGGMGIDG
                     RTLVTKNSFRMLNTLYTLGPSPEPNLTVLWSTKLPQGFKDFCSKVSIDTSSVQYENDD
                     LMRAYWGDDYGIACCVSAMRIGKQMQFFGARVNLAKTLLYAINGGVDEKSGVQVGPRF
                     EPITSEYLDYDEVMSKFEPFTDWLATLYVNTLNVIHYMHDKYSYEALEMALHDRDIFR
                     TMACGMAGLSVCADSLSAIKHAKVKTIRNEQGIAVDFEIEGDYPKYGNNDDRVDSIAV
                     ELVESFMNKIRKNKTYRNSYPTQSILTITSNVVYGKKTGNTPDGRRAGAPFAPGANPM
                     HGRDTNGALASLSSVAKLPYEHAQDGISNTFSIVPAALGKDMTERINNLSAMMDGYFA
                     QNAHHLNVNVFDRATLEDAMEHPEEYPQLTIRVSGYAVNFIKLTKEQQLDVINRTFHG
                     KMA"
BASE COUNT         4086 a         1305 c         1766 g         3601 t
ORIGIN      
        1 attttactat aaaaatttgt aataaagtga aaaaactagc ttttcatgaa ataatatttt
       61 ataatttaag attgtctttt taataaagat taacaaaaaa aatactataa ttagtggtat
      121 aatagttaga gttgaagatt ttaaataaag gtaggtgtaa ttaagttgga aatatactta
      181 gacaatagcg caactacaaa accttatcaa gaagttatag ataaaatggt ttatgcactt
      241 aatacggaat atggaaatcc ttcttctgtc catagaaaag gtgtagaagt tgaaaaagct
      301 ataaaagaag taagacaaga tatagctaaa tctctaggag cgaaagaaaa ggagatttat
      361 tttacatcag gtggtacaga gtgtaataat actataataa gaggtattac tagtttaaat
      421 aaaaaaagaa aaaatcacat aatatctact aacatagaac atccttctgt tttaaataca
      481 ttaaaagatt tagaagaaga tggttttgaa gtaacttatt tagaggtcgg aaaagatggg
      541 aaaataaata tagaggattt aaaaaatgcg ataaagtcaa ctacatgctt agtaagcatg
      601 atgcatgtta acaatgaaat aggaactata cagccaatag gtgaagttgg aaagtatttg
      661 aagggtttaa aagaaaaaat ttatttccat gttgatgcta ttcagtcata tggaaaaatt
      721 aattttagac catctaaata caatatagat tttatgagtg taagtgcaca taaatttcat
      781 ggtccaaagg gaattggatt tatgtatata aaagaaaata atcgccttaa gcctatgtta
      841 acaggtggtg gtcaggaaat tggaattagg tcgggaacag aaaatgtacc tggaatatat
      901 ggtcttggag aagctgttag aatactaaac aaagatttag atgttgttat ttcgaaagta
      961 aataacttaa aaaatatatt aaaaaatgaa ataattgata atatagaaga tataaaaatc
     1021 aattctccag aagatggagt atgtcatata ttaaatgtat catttagagg gacaaaagga
     1081 gaagttttac ttcattacct agagcaaaaa ggtatttatg tatcaactgg ctctgcatgt
     1141 tcttctaaaa agaaaggtag ttacgtatta aatgctatag gtcttacaaa tgaagaaata
     1201 aatggaacaa taagatttag tttatctgat atgaatacag aagaagaaat gttagaagct
     1261 gtgaaagttt tgaaagaatc aatttgtgac ttaaggtcaa taatgaaaag aaaataaaga
     1321 atactgtata gatagtgata ataaattagt ttaagaggtg aaatggtgta taatatatta
     1381 atagtaaagt atggagaaat tggagtaaaa ggaaagaata gatatatatt tgagaatagg
     1441 cttataagaa atataagaaa tatgttaaaa ccaattggaa gatttaatgt atataaagag
     1501 tatggaagaa tatatgttga tttagaagac tatgattatg aagaagtaat tgaagaagtt
     1561 agaaaagtat ttgggatagt gggtgtgtgc cctggagtaa gagctaaaaa agattatgat
     1621 acattaaaag aaatagcttt aaaaatgtta gaagaaaaaa tagaggctgg atataaaact
     1681 tttaaggtag agtcaagaag aggagataag tctttcgggt tgacttctca agaaatgagt
     1741 atggatatag gtggatactt attatcaaag gtaggagata ggattaatgt tgatgtaaga
     1801 aatccagaag ttaaaataaa gtgcgaatac agagaatttc atactatggt ctatagtgat
     1861 actatacctg gatatggtgg attgccactt ggaacgaatg gtagagctat gtctctttta
     1921 tcaggaggta tagatagtcc agtagctaca tggatggttg caaaaagagg tatggaggta
     1981 gaggcagttc acttccatag ttatccattt acaagtgaaa ggtcacagga aaaagttaag
     2041 gatttagcta aaatactggc aaaatactgt ggtagagtaa gacttcataa agttaacata
     2101 ttagaaatac aaaaagcaat tggtgagaat tgtaatgaag aagaagctac tattctttca
     2161 agaagattta tgatgaggat agcacagaga ctttctgaaa aaagacattg tgatgcttta
     2221 attacaggtg aaagtattgg gcaggttgca tctcaaacta tacaagggct tacttgtact
     2281 aatgccgttg tagacttacc agtgtttaga ccacttatag caatggataa atcagatata
     2341 gttgatatag ccaaaaaaat agggactttt gaaacatcta tagtgcctga agaagattgt
     2401 tgtagtgtat tttctcctag aaagcctgtc actaaaccta gattagagaa aatagaaaaa
     2461 tctgaaacag cacttgatat tgaaaaatta gtacaggatg ctattgacaa aatagaggta
     2521 gaggatattg agttttagca tacaagttat ttaattacta aattgaatat tgagtatatt
     2581 agtagttctg taagtatatt agtagttctg ttgaaaggat ttatgtagac aatttattaa
     2641 tatatagtat ttaaaaataa gtactataat tttatttaat gggaatgatt attatgaata
     2701 aaaagggttt tacattaatt gaattgttgg tagttatatc tataatagga attttagtta
     2761 tagtagctgt tccagcgtta tttagaaata tagaaaaaag taaggcagtt acatgtcttt
     2821 ctaatagaga aaatataaag actcaaattg ttattgcaat ggctgaggaa tcaagtaaag
     2881 acaagaatga agtcataaaa gaggtattag aaaacaaaga tggtaagtac tttgaaacag
     2941 aaccaaagtg taagtcaggt ggaatatatt cagcaacgtt tgatgatggt tatgatggaa
     3001 taactggaat agaaagcatt gcaaaagtgt atgttacttg tacaaaacat ccagatggta
     3061 ttgaaatggc tagggatata catcaaagta tgaaagattt gattgcatca tttgcacaag
     3121 acccttctat aataccagga gcttcaaagg gcaatgatga ttttagaaaa tatttattag
     3181 acaataaata taaaaatggg tggcctacaa ttccagatga atttaaggca aaatatggat
     3241 taagtaagga tacactatat atacaaccat atgcatataa tcctactaaa tctgatgcta
     3301 ctgtagttgt atttgcaaat aataagactg gaggtaattg gtatacttcc ctagtttacg
     3361 attatgatga aggtagatgg tataaaggta aaaatggtat ttctgttgca ggtaggtcat
     3421 gggatgttga cacagatagt gttaagtctg taaaaacaga gattcattct aaagagggat
     3481 ggggtccttt aaattaatat atcatgtttt attaatctgg tattgattaa actatagaaa
     3541 agagcagttt ctatagatga cgaataccag attttcattt atatgtataa ttaagatata
     3601 ttaaaagtat ttatattttt aagtcttcac atacaagcta aagataatta taataatatt
     3661 gtaaagaaat ttaattataa gattaatttt ctgaagattt agtatttgta ctaagaaata
     3721 cataaaaagg ggaatagata tgaataataa ttttcaagac aaccaaacaa taaatttaat
     3781 acaaagtcgt agaagtatac gaaaatttac aacagaacaa attagtgatg agcaagtaaa
     3841 cacattatta cactgtgcat ttgcagcacc ttcaggatgt aataaacagc cttggcacat
     3901 aactgttgtg caagaccaga aacttttaaa agagattagt gatgatactt tatctaggat
     3961 tcatgaagtg agtaatgttg agataaataa aaactttaag ttattttatg gtgctccaac
     4021 cgttttattt atttcttatg atgaaagtag ttcatgggct ccatatgata taggaatact
     4081 tacagggaat ataacaacag ctgcacaagc actagggctt ggaagttgta taataggaat
     4141 ggttagaggt ttatttacac ctgttgaaca aggggatatt gaaggtcttg tgagtgtatt
     4201 ggataaagaa gatgtaaaag aatcagagtc aataaagatg aagtttgata caaataaaaa
     4261 atacagagaa ctacttgata taccagaagg gtattctgta ccatttggta ttgctgtagg
     4321 tattccagat ggaaatttac caaatgctag agaggtagtt tacaaagttt ccagagttta
     4381 ggataaagta ttgcaagaac caatcagtta cttgaagaat taaaccagta atatacaaat
     4441 aaattgatgg aagaggaagc tatttaaaaa gtagtttaga tttttcgttg taaaataatt
     4501 aaataaagaa taaggtgata agtattttat ttattatctt attctttttt atttttgttt
     4561 tgtagaatga taaaaataag gattaagtgt aataaaatag aaaacaagta tgttaatttt
     4621 aagtatatgc tttaaaattt atccaagtta aaaatttaag atatcttttc agtataatgg
     4681 aaaaaatgtc aaaatattga aatagggaaa aaatagtgat ataataaaaa aaatagagaa
     4741 aaaaagtaac ccttagttgt aaaaaagtta ctatttattg aaaatttaga tatttttcta
     4801 aaaattatct atgttaatag ttaaatttat gaacattttt tgtttttatg ttaggatatt
     4861 tcttagaaat gaaatacttc ttaatttgat ttgatatgta tatttttata gctattttat
     4921 tataaaaaaa aagaaccctt ttacaacaaa tggaaactat gtacgtaata attaaaataa
     4981 aaaatattat tttatattta taaacattga cattctaatt ctgtagtgta atcgtatttt
     5041 ttattaattc ttacaaaatc aatgaaaata aggatatcca ttttaaagta cataaatttg
     5101 aaaaatccag agaaatatac ttaaattatg taagcaaaag aggggttgaa tcggctgaaa
     5161 atgtaatact agtaaatagt acatcaatcc tagataccct gtaagcaact ctattttcat
     5221 gtactaaaaa tgtacctatt ttattaactg aaaagaataa attaaatgta agtacataat
     5281 aagagataaa aaattaaaag caaaaaatat ttatataaat aaatataaaa aatgatataa
     5341 tccctattaa aaaatttata gatgatgaag aaatatcaaa atcttatatt ataggaagag
     5401 gcacttcttt gccaaaatat atagaaaagc aataccaaat ccaaagagaa taggctgaga
     5461 aaaaataaaa caaattcaag agtaatagaa aagctttata gaataaagaa ctgagaactc
     5521 tttatataat aaaaaatgga cttttaagag aaaatgattt aataaatgat ttaacatggt
     5581 gttttagcag gtgaaaataa atcaccagta atgattgtag aaaaattact ttatgaatct
     5641 caaaaaaact tagttaagag taagagattt gataagataa ctaaagttgg ggaaatgtgt
     5701 ttgatgagat aaaaaaatta gtaaaatagt ataatctaaa taagaatatt ttgttgatta
     5761 aactacacta atagtaatat tgtaggggga aaagatgaga gaagaatcga actctttaag
     5821 tttagaccat atagaaattt tctttgaact tttatctcaa agtacagaag attatatatt
     5881 tttttgggat ataaatagga ataaatttaa aatttcttca gcaatttttg atgaatttaa
     5941 cttaagtaaa gagatagaat ctgatttagt caattgttgg agtaaaattg tttatccgga
     6001 tgatgttcaa atatggaaag atgatataca agaattacta catggaaaaa aaggtgagca
     6061 caatttagaa tataggctaa ttaataaata taaagaaata gtatggattt cttgtagagg
     6121 taaagtttat gtggcggatg accccaaaac tatatttcta gttggcagaa taaagaatat
     6181 tggtgaaaaa aataaatttg attctatcac aggaacgtgg aatagagaac aatttgaaca
     6241 tagaatgaat tatcttataa aagagaaaat ttataaaaat ggtgctatgt ttatcatgga
     6301 tattgataat tttaaaaata taaatgaaaa atatggacat tcttatggtg acaaagtatt
     6361 gcgtgcaatt gctactgaag tattagaata tcttccaaaa gatgtaagat tgtataggtt
     6421 agatggagat gaatttgcat ttttttaccc tatgtgtact aaagaaacta tagagaaaat
     6481 atatgaaaag atacagatgt atacaaatac tcagcatgaa attgaatcaa ataagtacta
     6541 ttgcacagtg actgcaggag ttgctatgta tccagaagat ggagataatt atttagattt
     6601 atttaaacat gctgatattg cattggatat agcaaaaatt agtggtaaaa atagaattaa
     6661 gtttttttca caagagctct atgaaaataa actaaaggta atttcaatgc aacaaaaact
     6721 aagagagtgc gttgaaaata attttaatga ctttaagctg ttttttcaac cccaggtaaa
     6781 tgctgttaca aaagaggtaa taggggcaga ggtactttta agatggcatt cgagtactta
     6841 tggagaagta tctcctgttg aatttatacc aatactagaa cagagtaatt taattatacc
     6901 agttgggaag tggattataa aagaagctgt aaaacagtgt aaagaatggc ataaaataaa
     6961 tccagacttt aaaatatctg taaatgtatc gtatattcag ttaaaagaag atttttttag
     7021 agattttata gtagaatgtt tagtagagta tcaattaaga cctgaatttt taattttgga
     7081 attaacagag aattgttgga taccagatat aaatttacta aatgataaat ttattagttt
     7141 aaagggtata ggagtatata ttgcaataga tgactttggt acagggtatt catctttaaa
     7201 ttaccttaaa gaactgtctg ttaatataat aaaaattgaa agaagttttg ttaagaatat
     7261 tacatataat agttatgaat atacttttct tgaatatatt attaaattag ctcatattat
     7321 aaatttaaaa gtttgtgttg agggaataga gtcttatgaa gagtatgata tagtaaaaag
     7381 cttaggtgta gatattattc agggtttttt atttggaaga cctgtaagtg cctctgaatt
     7441 ttataaattt caactatcaa agtgatgtac ataaaatgag atatatagta tataaaaata
     7501 gggcaaagtg gaagttttga agtttattaa aaatttacac tttaccctat tttgttatgt
     7561 cttctataaa ggattaatat actacactaa ctattatata ctttcactcc aaatttagag
     7621 attatttcac tagctttttg gacatcttcc ttagtggcat caggaacatc ttttagttca
     7681 taatcgatac ctaaactttc ccatttgtgt attcccatag aatggtatgg tagcaattca
     7741 aatctttcta catttttcaa tgtagctaca aattgaccta gtttttctaa attatctata
     7801 tcatcagtaa tgccaggaac taaaacatgt cttatccata caggaatatt tcttgattct
     7861 aagtgtctag caagttttaa tgccttatcc ataccaacac cagtcaaatc aatagatttt
     7921 tcctcaacca tatgttttaa atcaagtaaa accaaatcag tattatctaa aactgggtct
     7981 atagtttcta tatctacgaa tccagatgta tccaagcaag tgtgtatatc attttctttt
     8041 gcttttttaa ataattcact taaaaattct ggttgaagag tggattcacc accagaggca
     8101 gttatacctc caccagaaaa cttcataaaa gaagtatact taagagcatc cgttattatt
     8161 tcatcaactg tgtattcttt tcctgattta atatcccatg tatccctgtt atgacagtat
     8221 ttgcatctaa gaggacaccc ctgaaaaaat aatatatatc ttattcctgg tccatctaca
     8281 gtaccaaacg tttctataga atgtatcttt ccattaatca tagagttcac ctcacaatat
     8341 attttaataa ccttatcaat agttataata tttctctaaa aaaggccatc ttataccaga
     8401 aataattcaa atataagata gccttttatt tttatttttt acacagtagt aatcttagtt
     8461 aaagtataaa aatttaaaga ctaagccatt ttaccgtgga atgttctgtt tataacatct
     8521 aattgttgct ctttagttaa ttttatgaag ttaactgcat atccagatac tcttatagtt
     8581 aattgtggat attcttctgg atgttccata gcatcttcta aagtagctct atcaaataca
     8641 tttacattta agtgatgagc attttgagcg aagtatccat ccatcattgc agaaagattg
     8701 tttattcttt cagtcatatc ttttcctaaa gcagcaggta ctatagagaa agtattagat
     8761 ataccatctt gagcatgttc atatggtaat ttagcaactg aagataatga agctaaagca
     8821 ccattagtat ctctaccatg cattgggtta gcaccaggag caaatggagc accagctctt
     8881 ctaccatctg gtgtattacc agttttctta ccataaacaa catttgaagt tattgtaagt
     8941 atagattgag ttggataaga atttctataa gttttattct ttcttatttt attcataaag
     9001 ctttcaacta actctacagc tatactatca actctatcat cattgtttcc gtattttgga
     9061 taatctcctt ctatttcaaa atcaacagct attccttgtt catttctaat agttttaacc
     9121 ttagcatgtt ttatagcaga taatgagtct gcacaaactg ataacccagc cataccacaa
     9181 gccatagttc taaatatatc tctatcatgt aatgccattt ctaatgcttc ataagaatat
     9241 ttatcatgca tataatgtat tacatttaaa gtatttacat ataatgttgc taaccaatca
     9301 gtgaatggtt caaatttact cataacttca tcataatcta agtactcaga agttataggt
     9361 tcaaatcttg gtccaacttg aacaccagat ttctcatcta caccaccatt tatagcgtat
     9421 aataaagttt tagctaagtt aactctagct ccaaagaact gcatttgttt accaattctc
     9481 attgcagata cacaacaagc tataccatag tcatctcccc agtatgctct cattaaatca
     9541 tcattttcat actgtactga acttgtatct atagatactt tagaacagaa atctttgaat
     9601 ccttgaggta atttagttga ccatagaact gttaagtttg gctctggaga aggtcctaat
     9661 gtatatagag tatttaacat tctaaatgag tttttagtaa ctaatgttct accatctatt
     9721 cccatacctc ctatacactc agttacccaa gttgggtctc cagagaatag gttattgtaa
     9781 tcaggagttc ttaggaactt aaccattctt aatttcataa caaaatggtc catatactct
     9841 tgtaattctt cttctgttac gattccagct tttaaatctc tttcaaagta tatatctaag
     9901 aaagtagatg ttctacctaa agacattgca gcaccatttt ggtctttaac agcacctaaa
     9961 taaccaaagt ataaccattg tacagcttct tttgagttag ttgctggttt tgatatatca
    10021 aatccataag attcagccat ttttttaagt tcatttaaag ctgatatttg ctcagttatt
    10081 tcttctctta atctgataac ttcctcatcc atgcaagaaa cttctaatga tttcttttgc
    10141 tcatttttat cttctattaa agcatcaaca ccgtatagag caactcttct gtagtcacca
    10201 attattctac ctctaccata agcatctgga agacctgtta ttataccaga ttttctagca
    10261 gctctcattt ctggagtata aacatcaaaa actccttggt tgtgtgtttt tctgtattta
    10321 gtaaatatat cttttatttc tgggtctaat tcatatccaa aagcttcgca tgaattttca
    10381 accatcttta taccaccata tggcatgaca gctcttttta aaggggcatc cgtttgtaac
    10441 ccaactattg tttctaattc tttatctaaa tatcctggag catatgcagc tattccagaa
    10501 acagtttttg tatcaacatc taaagtacca ccattttctc tttctttttt aaataggacc
    10561 attgcttcgt cccataattt tttagtattt tcagtggcac cagctaagaa agagtcattt
    10621 ccctcatatg gagaatagtt taattgtata aactctctaa catttatttc tttagtccat
    10681 cttcctgttt taaatccttg ccatgcattc attaagtatt tcctccttag atttaaatga
    10741 taaataatac tactaaaa
//
LOCUS       DACTZW010000114        10724 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.115, whole genome shotgun sequence.
ACCESSION   DACTZW010000114 DACTZW010000000
VERSION     DACTZW010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10724)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10724)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10724
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.115"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            210..1394
                     /locus_tag="JAM15_17060"
     CDS             210..1394
                     /locus_tag="JAM15_17060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799958.1"
                     /translation="MQKSVKKAKVTGSMLAIFGVASVLFSSHAGGGFATGNQETQYYV
                     QYGWTAPLMAILAMIILTATMREVIIMYNNNNCRNYKDLFCELWRPYPKLEIIWEIYY
                     YLMVLIAVSAVIAGAAAVFQSIGVNYFVAVFIIGVVLLVFTIFGAMLVSKAATAMTIA
                     ILVCTLTIFIVGIKAKVPEITEILSNRTSFTPGYIKPILNTFIYAGFQSVVIPTLAGC
                     SRPLLKNSKEATKAMIISFVMNAIALGLAVTMLMGWYREIIAAGQTTLPTLYVAGQSG
                     NHTIYIIYNVALFLCLMSTGVTTIFGLVNRFEDHKALSFLSSRMKRRVFTACAIMVVS
                     MLISLTGLSNIVKYGYGYCGYLGLFTIVIPFLTLGHYKNKKFAKENPEAKWPAELNEN
                     VN"
     gene            complement(1771..2880)
                     /locus_tag="JAM15_17065"
     CDS             complement(1771..2880)
                     /locus_tag="JAM15_17065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAT6799959.1"
                     /translation="MDFKSLGISENTINILKKSGITTPTPIQKESIKLIKEGKDVIAE
                     AQTGTGKTLAFLLPIFENISLDINDIQVLILSPTRELAIQITEEAMKLKESKDVSILA
                     AYGGKDIGSQIKKLKGNIHMIIATPGRLLDHLNRKTIDLSKLKTFVLDEADQMLLMGF
                     KNEVEAILKETSNKKQTLCFSATINSQVKKLAYRYTKNPVVVSIQKEEITLNNIKQEV
                     VETTDRKKLDALCKVLDEDNPFMAIIFCRTKRRVDNLEEALAIRGYNCQKLHSDIAQS
                     KRERIMKSFRNLDIQYLIATDVASRGLDISGVSHIYNYDLPETPEDYIHRIGRTGRAG
                     EEGYTCAFIDPKNERMLSEIETAIESKISRRIIEL"
     gene            3343..4536
                     /gene="nifV"
                     /locus_tag="JAM15_17070"
     CDS             3343..4536
                     /gene="nifV"
                     /locus_tag="JAM15_17070"
                     /EC_number="2.3.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocitrate synthase"
                     /protein_id="HAT6799960.1"
                     /translation="MCVISKDRAKEIKIVDTTLRDGEQTAGVVFANREKIMIAEMLSD
                     LGVDQIEVGIPTMGGDEKNVIKHICSRNLKSDIMAWNRAVIKDVEESISCGVDAVAIS
                     ISVSDIHIENKLRTSRGWVLENMAKTVEFAKKNGLYVSVNGEDASRADIDFLTEFINV
                     GKQAGADRFRYCDTVGVMNPFSIKNAIETLYERTNFDIEMHTHNDFGMATANALAGIA
                     AGANYVGVTVNGLGERAGNAALEEVLMALKCVYKCDLNNIDTRKFRGICEYVAQASGR
                     ILPTWKPVVGDNMFIHESGIHADGALKDPHNYEPFDPSEVNLERKIVIGKHSGRAAVI
                     NKLSEYEMYISPENATKLLNAIRATSIRLKRSLMDKEILQLYCDILAHEKGTTEEEAV
                     RGSYI"
     gene            4561..6486
                     /locus_tag="JAM15_17075"
     CDS             4561..6486
                     /locus_tag="JAM15_17075"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase"
                     /protein_id="HAT6799961.1"
                     /translation="MGDNIVYKIIKKHIVDGEAVAGSSIGIKIDQTLTQDSTGTMTYL
                     QLEAMGIDKVKTKRSVAFVDHNMLQQGFENADDHKYIQTVADKYGVYFSKPGNGICHQ
                     VFLERFSTPGDTLLGSDSHTPTAGGVGMMAIGAGGLDVALAMAGGAYYIKAPKVCKVN
                     LVGKLNNMVSSKDIILEVLRKQTVKGGVGKVYEYGGEGVKSLSVPQRATITNMGAELG
                     ATTSIFPSDEKTLEFFKSQGREDAWIELKPDADAVYDEEITINLDELKPLAAKPHSPD
                     NVDEVENIGKIKIDQVAIGSCTNSSYEDLMKVAQILKGNKVHKDVSLVIAPGSRQVME
                     MIARNGALADIISAGARILENSCGPCIGMGQSPGTDSVSLRTFNRNFYGRSGTLSAQV
                     YLVSPEVAAVSAIKGVLTDPREFDIKFTNLDVNEFLIDDSMIIKPADVGSNVEVVRGP
                     NIKPFPLNTELSQSIGGKVILKTEDNITTDHIMPSNAKLLPFRSNIPYLANYCFNTVD
                     TEFPQRAKDNNGGFIVGGDNYGQGSSREHAALAPLYLGVKGVIVKSFARIHKANLINS
                     GIIPMEFCDEKDYENISLLDNLEIPNILDNLGRGILEVKNTTKGTSFKVKVELSAKEV
                     DVLKAGGKLNYTKNQAN"
     gene            6508..7503
                     /locus_tag="JAM15_17080"
     CDS             6508..7503
                     /locus_tag="JAM15_17080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate/isopropylmalate dehydrogenase family
                     protein"
                     /protein_id="HAT6799962.1"
                     /translation="MYKVTLIPGDGIGPEVAKAMKKVVEATGVEIEWEEVNAGEAVIE
                     EYGTPLPEYIIDSIKKNKIAIKGPITTPVGKGFRSVNVTLRQALDLYVNLRPIKSFKG
                     IKSRYEDVDLVVVRENTEDLYAGIEHKIGDYAAESIKIITRSASERIVDFACNYVKDN
                     KRKKVTAIHKANIMKMSDGLFLDVFREVASKHGVEYDDLIVDAAAMNLVLNPENYDVM
                     VMPNLYGDILSDLGAGLVGGLGIIPSANIGKDCAIFEAVHGSAPQIAGQNKANPTALI
                     QSSVMMLRYLGEYENAQKIETALEKVFLEGSKLTVDLGGSASTTEFADEVCKYIV"
     gene            7830..8303
                     /locus_tag="JAM15_17085"
     CDS             7830..8303
                     /locus_tag="JAM15_17085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAT6799963.1"
                     /translation="MVGSVEVCLIKTLDSNILREVGTLSRAVNSINDIKYKELKLQKG
                     QFTFLTRICENPGINLVELSNMLKVDKATTTKAIQKLIKAGYVDKKQDKFDKRGYNLT
                     PTDKSLEVYELIIEEENRSIEICFDNFTDEEKQVVTKLLEKMSKNVENEWFKVKR"
     gene            8337..8831
                     /locus_tag="JAM15_17090"
     CDS             8337..8831
                     /locus_tag="JAM15_17090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAT6799964.1"
                     /translation="MIRKANMNDLESIMKIIKSTVEEMKTYNNTQWDENYPLEKDFVS
                     DIKKQDLYIYEVDGEVVGFICLNYEEPEEYLGLNWSSNKKAMVIHRMAVNPNFRKTGI
                     ASKLVDFAEKLAVENNVSYLKSDTYSINSKMNLLLTKCGFIKIGEMSFLGKEKSFYCY
                     DKIL"
     gene            8928..9449
                     /locus_tag="JAM15_17095"
     CDS             8928..9449
                     /locus_tag="JAM15_17095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H nitroreductase"
                     /protein_id="HAT6799965.1"
                     /translation="MIGFLKKRRSIRKYKDVEVEKEKLDKILKAALLAPSSKGLRTWE
                     FIVVDDKEKLINLSQCRTKGGGFFLKNAPLAIVIIADKEKNDVWIEDASIAASYIQLQ
                     AHELGLGSCWIQVRNRMHDDNIEADKYIREELKVPSKYSVECIISIGYSDEEKKAYSD
                     SDLDYKKVHFNNF"
     gene            9638..9949
                     /locus_tag="JAM15_17100"
     CDS             9638..9949
                     /locus_tag="JAM15_17100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAT6799966.1"
                     /translation="MGIFKTKMDEDWKVNYIKEFNEMRDSYESKLQKKQFEVDSLKSE
                     LDRLRSYKNSLKPKEKQITDDDINNIKSLRRDGLSYKEISNQTSWSKATVSRVLNGLY
                     D"
     gene            9977..10663
                     /locus_tag="JAM15_17105"
     CDS             9977..10663
                     /locus_tag="JAM15_17105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAT6799967.1"
                     /translation="MKYSYKKCIIDSILLMFIVQILRMILNYVLLSQFEFTLENFNII
                     NLISFTLVGLSLILFLKDNSLYNKVRNRKITEAFEENKNNILIEKCKLILFVVVLSLA
                     IIVTYCTKGYVLFNVTMMTLSVLIVPIFEELFFREYIWNYLSNFIKSKSKIICITSIL
                     SGIYNIGYIDVIRNYVILYNNSSYTFEVIISKIMIGTVFGIVLGLVKYRFRDVGFCIL
                     LRSLFAIFIR"
BASE COUNT         4100 a         1170 c         1940 g         3514 t
ORIGIN      
        1 tttcataaaa ttaaaaaaca aagtgaattt gaatactatt taaaaaataa aaaaatatat
       61 aaaaaatatt taatacaaag gtagaaataa gttgaaaatg taaagtcatt ggaaaaatat
      121 ggttgaattt aatgaacaaa aatgttattg ttttatcaat gaagtgttaa aataaaaact
      181 ttcaatatca ttttagggag gatgatttca tgcaaaaaag tgtaaagaaa gcaaaagtaa
      241 cgggatctat gttagccatt tttggtgttg caagcgttct ttttagttca catgcaggag
      301 gaggatttgc tacagggaat caagaaactc agtactatgt gcagtatgga tggacagcac
      361 cacttatggc aattttagca atgattatac ttactgctac catgagagaa gttatcataa
      421 tgtataataa taacaattgt aggaattata aggatttatt ttgtgagctt tggagaccat
      481 atccaaaact tgaaataata tgggagatat attactatct aatggtttta atagctgtaa
      541 gtgctgttat agcaggtgca gcagcagtat ttcaaagtat aggagtaaat tattttgtag
      601 ctgtatttat tattggagtt gtacttcttg tctttactat atttggtgct atgcttgtat
      661 ctaaagcagc tacagcaatg acaatagcta ttctagtatg tactcttact atttttattg
      721 ttggtataaa agctaaagta ccagaaataa ctgaaatatt atcaaataga acgagtttca
      781 cacctggcta tatcaagcca atacttaata cttttattta tgcaggtttt caatcggttg
      841 ttatacctac acttgcagga tgttcaagac cacttcttaa gaactcaaaa gaagctacta
      901 aggcaatgat aatttcattt gttatgaatg caattgcatt aggacttgct gtaactatgc
      961 taatgggatg gtatagagaa attattgctg ctgggcaaac aacactccct actctttatg
     1021 ttgcaggtca atctggaaat catactatat acataattta taatgttgca ttattccttt
     1081 gtttaatgtc tacaggagta actactatat ttggtcttgt aaatagattt gaagaccata
     1141 aagcactttc tttcctttcc tcaagaatga aaagaagggt atttacagct tgtgcaataa
     1201 tggtagtgtc aatgcttata tcacttacag gattaagtaa tattgttaaa tatggatatg
     1261 gatattgtgg ttatcttggt ctattcacta tagtaattcc attccttaca ctaggacatt
     1321 ataagaataa gaagtttgca aaggaaaatc cagaagctaa atggccagcg gaattaaatg
     1381 aaaatgtaaa ttagatgtag tagcaaaaaa tattgctaaa gagaatacta taaataagaa
     1441 tactatagat aatatatctg catgtttatt aagattattt gcaaaatcta atattaaaca
     1501 actataaaca agcaatataa aactaagaat aaaagataaa aagagggtgt ctcaaaatgg
     1561 acttttagtt tataaggcac tcttttttat atgaagtcaa atatattttc attattttga
     1621 caataaaaga gactaatcct actttggata gcctcttttt tctttaatat aaaatagtat
     1681 aacagcaaag tatagattga tacatgtttt ctgtagcttt ctatatatta cagtgtttgt
     1741 gtggcattgg tattttaagc aatctataaa ttataattct ataattcttc tactaatttt
     1801 agattctata gccgtctcta tttcacttaa cattcgttca tttttagggt caataaaagc
     1861 acatgtatag ccttcttcac cagctctacc agttctacca atacggtgga tgtagtcttc
     1921 tggtgtttct ggtaaatcgt aattatatat atgacttact ccagatatat caaggccacg
     1981 agaagctaca tctgtagcta ttaagtattg tatatctaaa tttctaaatg atttcattat
     2041 tctttctcgt tttgattgag caatatcact atgaagtttt tgacaattat atcctcttat
     2101 agcaagagct tcttcaagat tgtcaaccct tctcttagtc ctacaaaata ttattgccat
     2161 aaaaggatta tcttcatcta gtaccttaca taaggcatct aatttttttc tatctgtagt
     2221 ttctactact tcttgtttta tattattaag agtgatttct tctttttgaa tagaaactac
     2281 aacaggattt tttgtgtatc tataagctaa tttttttact tgagaattta tagttgcaga
     2341 aaagcatagt gtttgctttt tgtttgaagt ctcttttaaa atagcttcca cttcgttttt
     2401 aaatcccata agcaacattt ggtctgcttc atctaaaaca aaagtcttta acttactaag
     2461 gtctattgtt tttctattta gatggtctaa aagcctacct ggtgtagcta taatcatatg
     2521 aatatttcct tttagtttct ttatttgaga accaatatct tttcctccat atgctgcaag
     2581 aatacttaca tctttagatt ctttaagttt catagcttct tctgttattt gaatagctag
     2641 ttctcttgta ggagaaagta taagtacttg tatatcattt atatctaatg atatattttc
     2701 aaatatcgga agtaaaaaag ctagtgtttt tcctgttcca gtttgagctt ctgctattac
     2761 atcttttcct tcttttatta gtttaatact ttctttttgt ataggtgtag gtgttgttat
     2821 tcctgatttt tttagaatat ttattgtatt ttcactaatc cctaagcttt tgaaatccat
     2881 tgttatctta cctttcatga aaaattttct tttttattaa ccaattaata atatcatatt
     2941 tgtaagtatt tttagtaaat tttttaatta ttatttatat agcttaaaaa tatattaaga
     3001 tactttaaaa tggaatgtaa cttaaattaa attttagtag gaattttata ggtttatttt
     3061 taaaggtttt ttgaaaataa atctatttaa aaattaaatt aaaatgcaag aaaaacataa
     3121 taactttcat ttttaagaag ttttcacaaa aaagaaaaaa tatagtgcaa taaatgatac
     3181 aaagtaatat aatagattac aagatatgaa aagctaaaaa aataaattgc aaatgaaatt
     3241 aaaatgaata aaaaataaaa aaataatcat aagttagagg tatcaatgaa aaataagact
     3301 taatgttttt aaaattaaaa gtatactaag gggggcatta atatgtgcgt tatatcaaaa
     3361 gatagagcaa aggaaataaa aatagtagat actactttaa gagatggaga gcaaacagct
     3421 ggggttgtat ttgcaaatag agaaaaaata atgattgctg aaatgttaag tgacctaggt
     3481 gttgaccaaa ttgaagttgg tatacctact atgggtggag atgaaaaaaa tgtaataaag
     3541 cacatatgta gtagaaattt aaaatcagat ataatggctt ggaatagagc agtaataaaa
     3601 gatgttgaag aatctatttc ttgtggtgtt gatgcagtag ctatatcaat atcagtatct
     3661 gacattcata tagaaaataa attgagaact tctagaggct gggttttaga aaatatggct
     3721 aaaacagttg aatttgcaaa gaaaaatgga ttatatgttt cagtaaatgg agaagatgct
     3781 tcaagagcag atatagactt cttaactgaa tttataaatg ttggaaaaca agcaggggca
     3841 gatagattta gatactgtga tacagtagga gttatgaatc ctttttctat aaagaatgca
     3901 atagaaactc tttatgaaag aactaatttt gatatagaaa tgcatacaca taatgacttt
     3961 gggatggcaa ctgcaaatgc acttgcagga atagcagcag gagcaaatta tgttggtgtt
     4021 acagtaaatg gattaggtga aagagcagga aatgcagcat tagaagaagt tttaatggca
     4081 cttaagtgtg tttataaatg tgatttaaat aatatagata ctagaaaatt tagaggaata
     4141 tgtgagtatg tagcacaggc atcaggaaga atacttccta catggaaacc agtagttggg
     4201 gataatatgt ttatacatga atctggtata catgcagatg gagctttaaa agacccgcat
     4261 aactatgaac catttgaccc aagtgaagta aatcttgaaa gaaaaatagt aataggtaaa
     4321 cattcaggaa gagctgcagt tataaataag ttgagtgaat atgaaatgta tatttctcca
     4381 gaaaacgcta ccaagctatt aaatgctata agagctacat ctataagatt aaaaagaagt
     4441 ttaatggata aagaaattct tcaattatat tgtgatatac tagcacatga gaaaggcaca
     4501 acagaagaag aagcagttag aggttcatat atttaagata taattgttta ggaggaaaat
     4561 atgggagata atatagttta taaaataatt aaaaaacata tagtagatgg agaagctgtt
     4621 gctggaagtt caattggtat aaaaatagac caaactttaa cacaagattc tactggaaca
     4681 atgacatatc ttcaactaga agctatggga atagataaag taaagactaa aagaagtgtg
     4741 gcatttgtag accataatat gttacaacaa ggatttgaaa atgcagacga ccataagtat
     4801 atacaaacag tggcagataa atatggagtt tatttctcta agccaggaaa tggtatttgt
     4861 catcaagtat ttttagaaag attttcaaca ccaggagata cacttttagg ttctgatagc
     4921 cacacaccta ctgctggagg tgtgggcatg atggctattg gagctggtgg attagatgtt
     4981 gctttagcca tggcaggagg agcatactat ataaaagcac caaaagtctg taaggtgaat
     5041 ctagttggaa aattaaataa tatggtatca tcaaaagata taatattaga agtgttaaga
     5101 aaacaaactg taaaaggtgg agtaggtaaa gtttatgaat atggtggaga aggtgtcaaa
     5161 agcctatctg ttccacaaag agctacaata acaaatatgg gggctgaact tggagcaact
     5221 acttcaatct tcccaagtga tgaaaaaaca ctagaatttt ttaagagtca aggaagagaa
     5281 gacgcatgga tagagttaaa accagatgca gatgcagttt atgatgaaga gattactata
     5341 aacttggatg aattaaaacc attagctgca aaacctcata gcccagacaa tgtagatgaa
     5401 gttgaaaata taggcaagat taaaatagac caagtggcaa taggaagttg tacaaattct
     5461 tcttatgaag acttaatgaa agtagcacaa atcctgaaag gaaataaagt acataaggat
     5521 gtgagtttgg taatagcacc aggttcaaga caagttatgg agatgattgc tagaaatggg
     5581 gctttggcag atataataag tgctggagct agaatactag aaaattcttg tggtccatgt
     5641 attggtatgg gtcaatctcc aggtactgac tctgtgtctt taagaacttt caatagaaat
     5701 ttctatggta gaagtgggac tttgtcagca caagtatatt tagtaagtcc agaagtggca
     5761 gcagtaagtg caatcaaggg agtgcttaca gacccaagag aatttgatat taaatttaca
     5821 aatttagatg taaatgaatt tttgatagat gatagcatga taattaaacc tgctgatgta
     5881 ggaagtaatg tagaagtagt tagaggacct aatataaaac ctttccctct taatacagag
     5941 ctaagtcagt ctataggtgg aaaagttata ttaaagacag aagataatat aactactgac
     6001 catataatgc catcaaatgc taagttactt ccttttagaa gtaatatacc gtatcttgca
     6061 aactattgtt tcaatactgt agatacagaa tttcctcaga gagcaaaaga caataatggt
     6121 ggatttatag ttggtggaga taattatggt caaggttcaa gtagagaaca tgcagcttta
     6181 gcaccattat atctaggtgt taaaggggta atagttaaga gctttgcaag aatccacaag
     6241 gctaacttga taaatagtgg tataattcca atggagtttt gtgatgagaa agattatgaa
     6301 aatatatctc ttttagataa tctggagata ccaaatattt tagacaatct aggtagagga
     6361 attttagaag ttaagaatac aactaaagga acttctttta aggtcaaagt agaattgtca
     6421 gcaaaagaag ttgatgtatt aaaagctggt ggaaaattaa actacactaa aaatcaagct
     6481 aattaatatg aaaagaggga atattgaatg tataaagtga cacttatacc aggagatgga
     6541 ataggaccag aagttgcgaa agctatgaaa aaggtagtag aagctactgg agtagaaata
     6601 gaatgggaag aagttaatgc aggagaggca gttattgaag agtatggtac tccacttcct
     6661 gaatatatta tagatagtat aaaaaagaac aaaatagcta taaaaggccc aattactact
     6721 cctgtaggta aaggatttag gagtgtaaat gtaactttaa gacaggcatt agatttgtat
     6781 gtcaatttaa gacctattaa aagttttaag gggataaaat caagatatga agatgttgat
     6841 ttagtggttg taagagaaaa tacagaagat ttatatgctg gaatagaaca taaaataggt
     6901 gattatgcag ctgaaagtat aaagataata acaagaagtg caagtgaaag aatcgttgat
     6961 tttgcatgta actatgttaa agataataag agaaaaaaag ttacagctat acataaggca
     7021 aatataatga aaatgtctga tggattgttt ttagatgtgt ttagagaagt tgcatcaaaa
     7081 catggtgtag aatatgatga tttgattgta gatgcagcag ctatgaactt agttttaaat
     7141 ccagaaaatt atgatgtaat ggtaatgcca aatctttatg gagatatact atcagattta
     7201 ggtgctgggc ttgttggagg tttaggtata attccaagcg caaatattgg taaagattgt
     7261 gcgatatttg aagctgttca tggaagtgct ccacaaatag caggtcaaaa taaggctaat
     7321 ccaacagcac ttattcaatc atcagtaatg atgcttagat acttaggtga atatgaaaat
     7381 gcacaaaaaa tagaaacagc tttagaaaaa gtatttcttg aaggaagtaa attgactgta
     7441 gatttaggtg gctcagcttc tactacagag tttgcggatg aggtgtgtaa gtatattgta
     7501 tagattttat ttagggaaaa agtaaaatat agattgaagg aaagaggctt tctcaaaata
     7561 gagataagcc tttttttatt ggaatgataa aatatatttg attttataca aaagagagtt
     7621 cctcataaac gaaaaagtta attttgggat atccatttta attttaaaat taattgatta
     7681 atacgcaaag aaagattaaa caaatttatt atttttaatt gaactttcaa ccaaaatatg
     7741 gtaaaattta aaaaagttga actttcaact aaaaataaat atatttatta tgtgaaattc
     7801 tataaaacag aaactatttg actttagtca tggtaggttc agtggaggtg tgtttgatta
     7861 agactttaga tagtaatata ttaagagaag taggtacttt atctagagca gtaaattcaa
     7921 taaatgatat taagtacaag gaattaaagt tacaaaaagg acaatttaca tttttgacaa
     7981 gaatctgtga aaatcctggt ataaatcttg tggaattatc aaatatgtta aaggtagaca
     8041 aggctacaac aaccaaggct atacaaaaat taataaaggc aggatatgta gataaaaagc
     8101 aggataagtt tgataaaaga ggatataatt taactccaac tgataaatct ttggaagttt
     8161 atgagttgat aattgaagaa gagaatagaa gtatagagat atgttttgat aattttacag
     8221 atgaagaaaa acaagtggta actaagttat tagaaaaaat gagcaaaaac gtagaaaatg
     8281 aatggtttaa agtaaagaga tagtaaataa atacattaac ttaaggagat atttttatga
     8341 ttagaaaagc gaatatgaat gatttagaaa gcattatgaa aattataaaa tctacagtgg
     8401 aagaaatgaa gacttataat aatacacaat gggatgaaaa ctatccatta gaaaaagact
     8461 ttgtttcaga tattaagaaa caagatttat atatttatga agtggatgga gaagtagtag
     8521 gatttatatg tcttaattat gaagagccag aagaatattt aggcttaaat tggtcatcta
     8581 ataaaaaagc aatggtaata catagaatgg ctgtaaatcc aaactttaga aagacaggaa
     8641 tagcatctaa gttagttgat tttgctgaaa aattagctgt agaaaacaat gtatcatact
     8701 taaagagcga tacatattca ataaactcaa aaatgaattt attacttaca aagtgtggtt
     8761 ttataaaaat cggagaaatg agttttttag gaaaggagaa atctttctac tgttatgata
     8821 aaatattata aagagcattt ataatacaag gggtaaataa tagattttca gcattagtaa
     8881 gggcataata taacccagta tatgctatta tgaaagggat gatttatatg attggatttc
     8941 taaagaaaag aagaagtatt agaaaataca aggatgttga agtagaaaaa gaaaaattag
     9001 ataaaatatt aaaagctgct cttttagctc catcatcaaa ggggcttaga acatgggaat
     9061 ttatagtggt agatgataaa gaaaagctaa ttaatttatc tcaatgtaga actaagggtg
     9121 gtggattttt cttaaaaaat gcacctttag ctattgtaat tattgcagat aaagaaaaaa
     9181 atgatgtttg gatagaggat gcaagtatag ctgcttcata catacaactt caagctcatg
     9241 aactaggttt aggttcttgt tggatacaag taagaaatag aatgcatgat gataatatag
     9301 aagctgataa gtacattaga gaagaattaa aagtacctag caagtacagt gtagaatgta
     9361 taatttctat aggatattct gatgaagaaa agaaagcata cagtgactct gatttagact
     9421 ataaaaaggt tcattttaac aacttttagt atataatatg ttgtattaag acattatatt
     9481 tttttctatt gttaatatat acttaaaatt gtaaaaatat atctgaattt tactaactta
     9541 tctaggggtt atgtacaagg attttaaaga taaatataga aattaatgtt tataatcgat
     9601 acataacttg agtaacaaaa tttaaggagg ttaaagtatg ggtatattta aaacaaaaat
     9661 ggatgaggac tggaaagtaa actacattaa agagtttaat gaaatgagag attcttatga
     9721 gagtaaactt caaaaaaaac agtttgaggt agatagtttg aaatcagaat tggatagact
     9781 aagaagctat aaaaatagcc ttaagccaaa agaaaaacaa attactgatg atgatataaa
     9841 taatataaag agtttaagaa gagatggctt aagctataaa gaaatttcaa atcaaacaag
     9901 ttggagcaaa gcaactgtaa gtagggtatt aaatggactt tacgattagc atatacatgg
     9961 ggtgatttaa attgggatga agtatagtta caaaaaatgc ataatagatt ctattttatt
    10021 gatgtttata gttcaaatat taaggatgat tttgaattat gtacttctaa gtcaatttga
    10081 atttactctt gaaaatttta atattataaa cttaatttct tttacattag ttggtttatc
    10141 gttaatttta tttttaaaag ataattcttt gtataacaag gttagaaata gaaaaatcac
    10201 agaagctttt gaagaaaata aaaacaatat acttattgaa aagtgtaagc ttatactttt
    10261 tgttgtggtt ttatctttag caataattgt aacttattgt actaagggat atgtactttt
    10321 taatgtaact atgatgactt tgtctgtatt gatagttcca atatttgaag agttattttt
    10381 tagagaatat atatggaact atctaagtaa ttttataaag tcaaagagta aaattatctg
    10441 tataacatct atactatctg gaatttataa tataggatac atagatgtta taagaaatta
    10501 tgtaatattg tataacaatt caagctacac ctttgaagtt attatttcaa aaattatgat
    10561 aggtactgtt tttggtattg tacttggatt agttaagtat aggtttagag atgtagggtt
    10621 ttgtatatta ttgaggagct tatttgctat atttattagg tagatagtat aatcggttta
    10681 taaggttgtt ttaaatttaa ttttaaatca accttatttt attt
//
LOCUS       DACTZW010000115        10722 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.116, whole genome shotgun sequence.
ACCESSION   DACTZW010000115 DACTZW010000000
VERSION     DACTZW010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10722
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.116"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            237..1001
                     /locus_tag="JAM15_17110"
     CDS             237..1001
                     /locus_tag="JAM15_17110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAT6799968.1"
                     /translation="MQIIDININNIDSRHICCSISEKKGENCVFSKKAWMKNNFDKGL
                     AFKRFDVRGKAFIEYIPAENAWCPITADNYIFINCFWISGKFKGQGYSNLLLQECVDD
                     AKSKGKYGLVVLSSSKKMPFLSDAKYLKYKGFCLADTSEPNYELLYFPFTDNAPIPCF
                     KNCVKKRKLNENGIVLYYSNQCPHTEKYAPILKKIANSRGIDVNLIKFETAKEAQNAP
                     APFTTYSLFFNGEFVTNEILSEKKIEKFLDTNIKKI"
     misc_binding    1224..1437
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1691..2725
                     /locus_tag="JAM15_17115"
     CDS             1691..2725
                     /locus_tag="JAM15_17115"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HAT6799969.1"
                     /translation="MNKIKVGIIGATGYVGAELIRLLMNHDKVEVTAIGSNSYVGKNI
                     VDIYPSIGYKNNMICIENEKVIDMCDVVFTALPHGVSEKFVIKAIKSKKKVIDLGADF
                     RIKDEEVYSKWYGVSFIDKILHKKAVYGLSEIYKEDIKDADIIANPGCYPTSISLPLM
                     PLLSSKLIKNNNIIIDSKSGLTGAGRELSISSHFTEVNENITAYKIGKHRHTPEIEQN
                     LSESCKEKVSVVFTPNLIPVNRGILSTIYCTKEDNISINDIHRKLTDYYEFKEFIEVL
                     PLDKVASLKNVRFSNKCVISLHENGDTLIICSAIDNMIKGAAGQAIQNMNIIFGIEEN
                     TGLKNIAPSF"
     gene            2767..3984
                     /gene="argJ"
                     /locus_tag="JAM15_17120"
     CDS             2767..3984
                     /gene="argJ"
                     /locus_tag="JAM15_17120"
                     /EC_number="2.3.1.1"
                     /EC_number="2.3.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate
                     N-acetyltransferase/amino-acid acetyltransferase ArgJ"
                     /protein_id="HAT6799970.1"
                     /translation="MEIIKGGVTVSEGFFASGIHCGLRKNKEKRDLALVYSDVLCDAA
                     AVVTQNKVKGNPVYVTQEHIKNGKAQAIIVNSANANTFNGKEGLINAYKMAKFTSDKL
                     NIKENDVLVASTGVIGKPLNINLIEENMDELVNNLSKQGHIGAREAIMTTDIIKKEIA
                     VAIMYGDKKITIGGMAKGSGMIHPNMATTLGFITTDANIDGVLLKEALKIAVDKSFNR
                     VSVDGDTSTNDMVMILANGKAKNDRINKKDEHYQVFLSALTYVCIELAKLVAKDGEGC
                     TKLIECYINGALSEEHAVKLAKTVISSSLVKTAVFGADANWGRILCALGYAGEEIDME
                     KVDIIFESMKGYIEVCKNGNGLDFNEEKAKKILEDDEISILVDLNMGNARGNAWGCDL
                     SYDYVRINGSYRN"
     gene            3999..4859
                     /gene="argB"
                     /locus_tag="JAM15_17125"
     CDS             3999..4859
                     /gene="argB"
                     /locus_tag="JAM15_17125"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HAT6799971.1"
                     /translation="MINIEKANTLIEALPYIEKHQGKTIVVKYGGSAMKKDGLKESVM
                     EDLVLMSYVGINIVLVHGGGAEINKMLAKVDIESKFVNGLRYTDEETMEIVKMVLAGK
                     VNKDLVNKIHTKGGKAVGLCGIDNNMILCDPYKNYELGFVGEIKKVNVELIESCLKSG
                     YISVIATIGVGDDGETYNINGDTAASAIAKELNADKLILLTDVPGLLREPDEEKSLIT
                     EVILEDVDKLFEEGIITGGMIPKIEGCVDALNNGVNRVHILDGRVPHSIITELFTDSG
                     IGTLIRKENE"
     gene            4889..6076
                     /locus_tag="JAM15_17130"
     CDS             4889..6076
                     /locus_tag="JAM15_17130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase family protein"
                     /protein_id="HAT6799972.1"
                     /translation="MNNNNTISKWNEYFIDTYNQPNFVIDYGEGSCFFDTNGNKYIDF
                     TSGYGVSSLGYSNSNLKNALKEQVDKLLHTSNLYFNEPVLYSGEKIINSSGMAKVYFC
                     NSGTEANETAFKIARKYSSDKYGNGRGTIISLKDSFHGRTMMSLMATGMDKYHKYFYP
                     LPEGFKYIERNNIEDLKNNLDSTVCAIILEAIQGEGGVNVLEKDYVLEIVKICQEKDI
                     VVIFDEVQCGIGRTGKLFGYEYFDVKPDIVTVAKGLGAGIPVGGVLVNKKLSKVLGKG
                     DQGTTFGGNLLAMVAASVVLDEISKDGFYNEVLEKGNYIRKSIESFNNKVVLKTKGIG
                     LMIGIETNIESSIIEEKARKKGLLILTAGKNVLRFLPPLTISYKEIDEALEILKDILL
                     EIN"
     gene            6185..7207
                     /gene="argF"
                     /locus_tag="JAM15_17135"
     CDS             6185..7207
                     /gene="argF"
                     /locus_tag="JAM15_17135"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HAT6799973.1"
                     /translation="MNNISLKGKSFLTLKDFTKEEIRYLLTLSSYLKTKKKVGIKGDL
                     LQGKNIALLFEKTSTRTRCSFEVAAHDEGAYVTYLGPNDCHMGKKESVSDTAKVLGRF
                     YDGIEFRGFKQETVESLAKYSGVPVWNGLTDEYHPTQILADFLTVIENVDKDLNKVKF
                     VYVGDARNNMGNSLMIGCAKMGIHFVALAPKELWPNEELVKEMKEIAKKSKGDIMLTE
                     NIDDVKGADVIYTDVWVSMGEEEQYEARINQLKDYQVNMDMIKKTENENVIFLHCLPA
                     FHDLETKVAQKIYEKFGLSELEVTNEVFNSKYSKVFEEAENRMHTIKAVMVSTMTDVN
                     MNNNLI"
     gene            7334..7951
                     /locus_tag="JAM15_17140"
     CDS             7334..7951
                     /locus_tag="JAM15_17140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4878 domain-containing protein"
                     /protein_id="HAT6799974.1"
                     /translation="MKKIILALTTFLLAISLTACSSAKPEDTIDSFFNSAKKFDFEGM
                     NKVMENNDEKYKDILKELDTKDPNAQYVLDYLKQNASKITYTIKDSEVKGDKATIKVE
                     CKFIDSTPLLQEIVAEAFTKMIGMSFSGQDLTDEKTTEMLVSIMKEKQKSVKETYVTK
                     TVEFECSKKDNKWIISSVNDAVADVLLSNLVTAGQEFSNSMNTLE"
     gene            complement(8171..8869)
                     /locus_tag="JAM15_17145"
     CDS             complement(8171..8869)
                     /locus_tag="JAM15_17145"
                     /EC_number="5.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019227200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid racemase"
                     /protein_id="HAT6799975.1"
                     /translation="MNEKLIGILAGMGPRSTAPFVDLIIDECQSQYGAKYDDEFPKMM
                     IYSLPTPFYIDRPINHELMKETIIDGLQKLESTGVNFIAMPCNSAHIYFKELKESINI
                     PILNIVEETVKKLPTISQKVTLFSTSSTFESTIYQNGIIHNGHEFIFKDEWQIKLNNL
                     IQNIKMDKENPHNIDIWNKLIEDVKNESIENIVIACTDLNVVLEKSYPSINIVDSSKC
                     LAESVVNKYLKLVK"
     gene            complement(9031..9420)
                     /locus_tag="JAM15_17150"
                     /pseudo
     CDS             complement(9031..9420)
                     /locus_tag="JAM15_17150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428929.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallo-hydrolase"
     gene            complement(9526..10692)
                     /locus_tag="JAM15_17155"
     CDS             complement(9526..10692)
                     /locus_tag="JAM15_17155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017752472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAT6799976.1"
                     /translation="MKGGVRKRGKKWYYYFDAGIVNGKRKKVEKVGGETKKEAEKALR
                     DAINEYENAGIVFDETNMSLSNYLDFWYKEYVLLNCKYNTQVNYRNLIKNHIEPELGK
                     YKLKSINPAIIQEFLNNKTKETYTQNGEERRYTRGNLKAIYGVLNSALKSAVYPYKLI
                     KENPAQYTNIPKNIIDTKKDSENKTITLDEFNKILEIYPKNTNIYIPLLIGFHTGMRK
                     GEILGLCWDNIDLDNNIIKVRKNLIKRKVSEFELTSPKTKTSIRDIRIGDTLSKVLKE
                     EKLNQKKQKIKLGKWYTETEYDWVCRKKDGSFVNHNNIDACVRTINKKLNLDFNFHCL
                     RHTHATLLLENGANIKYIQQRLGHSQLSTTMDTYSHVTSKMESETIDILENLVR"
BASE COUNT         4159 a         1136 c         1787 g         3640 t
ORIGIN      
        1 caatacaatt tgttttataa atttagaata ttatgataat atatagttta tatatagtgt
       61 ggttagacct agaatgtatt taattatata tgcaatttga taattcaaat aatctaaaaa
      121 taatattatg taaaataaaa atatatatga catgatgttg ttgtattcaa aatattaaga
      181 taaaaatata tagaatatat ttaaaaatta ttatgtaatt agaaaaggag ataagtatgc
      241 agattattga tataaatata aataatattg acagtagaca tatatgctgt tcaatttctg
      301 aaaaaaaagg agaaaattgt gttttttcta aaaaagcttg gatgaaaaat aattttgata
      361 aaggtctagc ctttaaacga tttgatgtaa gaggtaaagc ttttatagaa tatattccag
      421 cagaaaatgc atggtgtcct attactgcgg acaattatat atttattaac tgtttttgga
      481 tatctggaaa atttaagggt caaggatatt ctaatctatt gctacaagag tgtgttgatg
      541 atgcaaaatc aaaaggtaaa tatggattag ttgtgctttc gtctagtaaa aaaatgcctt
      601 ttttatctga tgctaaatat ctaaaatata agggcttttg tttagcagat acatcagaac
      661 caaattatga gctattatat tttcccttta ctgataatgc tcctattcca tgttttaaga
      721 attgtgtaaa aaaaagaaaa ttaaatgaga acggtatagt tttatattac agtaatcagt
      781 gtccacatac agaaaaatat gctcctattt tgaaaaaaat tgcaaattct agaggtattg
      841 atgtaaatct tataaaattc gaaacagcaa aagaagcaca aaatgctcct gcaccattta
      901 ctacatacag tctttttttt aatggtgaat ttgtaaccaa cgagatactt tctgagaaaa
      961 agattgagaa atttttagat accaacatta aaaaaattta actaaaaata gatgtaaata
     1021 ttgtattttg agattacatt attttataat ccaatatatt ttggaaattt cttaagttga
     1081 tgaatgataa tataaagatt ataactcaat ttagatacaa aatgctggaa attaactata
     1141 tagaaaatat ttccaaaaat ttaaaaatta tattgacaaa gttaaaaaaa taaactatca
     1201 tataaaacaa taagaaaata aattgaaatc ctgtgaaaaa gagagtagca taaagctagt
     1261 tgatagagag ctgggaatgg tggaagccta gtaacgaatt ttattgtgaa tagagctttg
     1321 gaggagatta ccagaagtaa tagtatggta attggtgaat ctcgccttaa gagattagag
     1381 tgggtaagat tatcttatca attagagtgg taacgcgggt gtatattcgt ctcttggtct
     1441 ttgaccaaga ggctttttta attttaaatg tacattttgt agatactttt taatttgagt
     1501 tttaatgatt attgtaattt taccaataag agtggtaccg cggaaaatcg cctcttagta
     1561 tttataatgc taaggggttt tttgttttaa ttagaatatt ttaatctaca tattatcaaa
     1621 tgattatcat atagtaaagt ggaaagatag aattttaata ctatttgaat ataaaaatgg
     1681 agggaacaaa atgaataaaa taaaagttgg tattattggc gcaactggat atgtcggggc
     1741 agagttgatt agattattaa tgaatcatga taaagtcgaa gtgacagcaa taggttcaaa
     1801 ttcgtatgtt ggaaaaaata tagttgatat atatccaagt ataggatata aaaataacat
     1861 gatatgtata gaaaatgaaa aagttataga tatgtgtgat gttgtgttta cagcccttcc
     1921 acatggagtt agtgaaaagt ttgtaataaa agcaattaaa tcgaaaaaga aagttataga
     1981 tttaggtgct gactttagaa taaaagatga agaagtatat agtaaatggt atggagtatc
     2041 ttttatagat aaaatcttac ataaaaaagc tgtatatgga ttaagtgaaa tatacaaaga
     2101 agatataaaa gatgcagata taattgcaaa tcctggatgt tatccaacta gtatttcttt
     2161 accattgatg ccattactaa gttctaaatt gataaaaaat aataatataa taattgattc
     2221 taaatcaggt cttacaggtg ctggtagaga attatcgatt agtagtcact ttacggaggt
     2281 taatgaaaat atcactgcat ataaaatagg gaaacacaga catactccag aaatagaaca
     2341 aaatttaagt gaatcctgca aagaaaaagt aagtgtagtt tttacaccaa acttaatccc
     2401 agtaaatagg ggaatcttat caactatata ttgtacaaaa gaagataata tttctataaa
     2461 tgatatacat agaaaattaa ctgattatta tgaatttaaa gaatttatag aagttctccc
     2521 attagataag gtagcttctt taaagaatgt taggttctca aataaatgtg tcatatcatt
     2581 acatgaaaat ggagatacat tgataatctg ttcagctata gataatatga ttaagggagc
     2641 agcaggtcaa gctatacaaa acatgaatat aatatttggt attgaagaaa atacaggttt
     2701 aaaaaatatt gcaccatcat tttagtaatg aaaaaatact aaactcatat aattaggagg
     2761 ataaatatgg agattataaa gggtggagtt acagtttcag aaggattttt tgcttcaggg
     2821 attcactgtg gcttgagaaa aaataaagaa aaaagagatt tagctttggt ttattcagat
     2881 gttttatgtg atgcagcagc agtagtaact caaaataaag taaagggcaa tcctgtttat
     2941 gttacacagg aacacattaa aaatggaaaa gcacaagcta tcatagtaaa tagtgctaat
     3001 gctaatacct ttaatggaaa agaaggactt ataaatgctt ataaaatggc taaattcact
     3061 agtgataaat taaatattaa agaaaatgat gttttggttg catctacagg tgtcatagga
     3121 aagccattaa atataaattt aatagaagaa aatatggatg aattagtgaa taatctaagt
     3181 aaacaaggtc atattggagc aagagaagct attatgacaa ctgatattat aaaaaaagaa
     3241 atagcagtag caataatgta tggagataaa aaaataacta ttggaggtat ggcaaaaggt
     3301 tctggcatga tacatcctaa tatggcaaca acgttaggat ttataactac agatgcaaat
     3361 attgatggag ttttgctaaa agaagctttg aaaattgctg ttgataaaag ttttaataga
     3421 gttagtgtag atggagatac aagtactaat gatatggtga tgattctagc aaatggaaaa
     3481 gcaaaaaatg atagaataaa caaaaaagat gaacattatc aagtattttt gagtgcactt
     3541 acatatgtct gtatagaact tgctaaactt gttgcaaaag atggagaagg atgtacaaaa
     3601 ctaattgaat gttatataaa tggagcatta agtgaagaac atgcagtaaa attagcaaaa
     3661 acagttatat cttcttcatt agtaaagaca gctgtatttg gagctgacgc aaattggggt
     3721 agaatactgt gtgctttagg ttatgcaggt gaagaaatag atatggaaaa agttgatatt
     3781 atttttgaga gtatgaaagg atatattgaa gtatgtaaaa atggaaatgg attagatttt
     3841 aatgaggaaa aagcaaaaaa aatccttgaa gatgacgaaa taagtatatt agtagattta
     3901 aatatgggca atgccagagg aaatgcatgg ggatgtgatt taagctatga ttatgtaaga
     3961 ataaatggaa gttatagaaa ttaggaggat atactttaat gattaatata gaaaaagcaa
     4021 atacacttat agaagcttta ccatatatag aaaaacatca gggaaagact attgtagtta
     4081 agtatggtgg aagtgcaatg aaaaaagatg gtctaaaaga atctgttatg gaagaccttg
     4141 tattaatgag ttatgttgga atcaatatag ttttagtaca tggtggaggg gcagaaatca
     4201 ataagatgct agcaaaagtg gatatagaaa gtaaatttgt aaatggtctt agatatacag
     4261 atgaagagac catggaaatt gtaaaaatgg tacttgctgg aaaggttaat aaagacctag
     4321 taaataaaat acatacaaaa ggtggaaaag cagtagggct ttgtggaata gataataata
     4381 tgattttatg tgacccatat aaaaattatg aacttggatt tgtaggagaa atcaaaaaag
     4441 taaatgttga gcttatagaa tcttgtctaa agtcaggtta tatttcagta attgcaacta
     4501 taggtgttgg agatgatgga gagacttata atataaatgg tgacacagca gcttctgcta
     4561 tagctaaaga gttaaatgca gataaattga tacttcttac agatgtccct ggtttgttaa
     4621 gagagccaga tgaagaaaaa tcattaataa cagaagttat attagaggat gttgataaat
     4681 tatttgaaga aggtataatt actggaggta tgatacctaa aatagaggga tgcgtagatg
     4741 ccttaaataa cggagtaaat agggtacata ttttggatgg aagagttcca cattctataa
     4801 taacagagct atttactgat agtggaatag gtacattaat aagaaaagaa aatgaataaa
     4861 attataagtt taagagggga gaataagaat gaataacaac aatacaattt caaaatggaa
     4921 tgaatatttt atagatacat ataaccaacc caattttgtc atagattatg gtgaaggaag
     4981 ttgttttttt gatactaatg gcaataaata catagatttt acaagtggat atggagtatc
     5041 ttctcttggg tatagtaata gtaatttaaa gaatgctcta aaagagcaag tagataaatt
     5101 attacatact tcaaatttat attttaatga gccagtgttg tattcaggag agaaaataat
     5161 taattcaagt ggaatggcta aagtatattt ttgtaattct ggaacagaag caaatgaaac
     5221 agcattcaaa atagcaagaa agtatagtag tgacaaatat ggtaatggta gaggaactat
     5281 cataagttta aaagactctt ttcatggtag aacaatgatg tctttaatgg caactggtat
     5341 ggacaaatac cataagtatt tttatcctct tcccgaaggt tttaaatata tagaaagaaa
     5401 taatattgaa gatttaaaaa ataatcttga ttccacagtt tgtgcaataa ttcttgaagc
     5461 gattcaaggc gaaggtggag ttaatgttct tgaaaaagat tatgttttgg aaatagtaaa
     5521 aatatgtcaa gaaaaggata ttgtagtgat ttttgatgaa gtccaatgcg gtataggaag
     5581 aactggtaaa ctttttggct atgaatattt tgatgtaaaa ccagatatag ttaccgtagc
     5641 aaaagggttg ggagcaggaa taccagtagg aggagtattg gtaaataaaa aactttcaaa
     5701 agtactagga aaaggagacc aaggtacaac ttttggaggt aatttattag ctatggtggc
     5761 agcttcagtt gtattagatg agatatctaa agatggtttt tataatgaag tattagaaaa
     5821 aggaaattat ataagaaaat ctattgaaag ttttaataat aaagttgtat taaagacaaa
     5881 aggtattggt ctaatgatag gaattgaaac taatattgaa tctagtatta tagaagagaa
     5941 agctagaaaa aaaggattgc ttattttgac tgctggaaaa aatgtattga gatttttacc
     6001 accattaaca atcagttata aggaaataga tgaggctctt gaaatcctaa aagatatatt
     6061 actagagatt aactaaatat tcaaaaaata gttaattaaa gataaaaatt agaagtaaat
     6121 aaaaaagtaa agtgctaaca agtttaattg aatttaaaaa gtttataaga aggggcgaat
     6181 taatatgaat aatataagtt taaaaggtaa gagttttttg acattaaagg attttacaaa
     6241 agaagagatt agatatttat taactttatc aagttattta aaaactaaga aaaaagttgg
     6301 tataaaaggc gatttgctac aaggaaaaaa tatagcttta ttatttgaga aaacatcaac
     6361 aagaactaga tgttcatttg aagtagcagc tcatgatgaa ggagcatatg taacttatct
     6421 aggtccaaat gattgtcata tgggtaaaaa agagtctgta tcagatacag caaaagttct
     6481 aggaagattc tatgatggaa tagaatttag aggctttaaa caagaaacag ttgaaagtct
     6541 agcaaaatat tctggtgtac ctgtttggaa tggacttaca gatgaatatc atccaacaca
     6601 aatactggca gattttttaa cagtaattga aaatgtagat aaagatttga ataaagttaa
     6661 atttgtatat gttggtgatg ctagaaataa tatgggaaac tcactgatga taggatgtgc
     6721 taaaatggga atacatttcg tagcactagc acctaaggaa ctttggccaa atgaagaatt
     6781 ggttaaggaa atgaaggaaa tagccaagaa atccaaagga gatataatgt tgactgaaaa
     6841 tattgatgat gttaaaggtg cagatgttat atatacagat gtatgggttt ctatgggaga
     6901 agaggagcaa tatgaagcaa gaataaatca acttaaagat tatcaagtaa atatggatat
     6961 gataaagaaa actgaaaatg aaaatgttat atttttacac tgtcttccag catttcatga
     7021 tttagaaact aaggttgctc agaagattta tgaaaagttc ggattatcag aattagaggt
     7081 tacaaacgag gtatttaatt caaaatattc aaaggtattt gaagaagctg aaaatagaat
     7141 gcatacaata aaagctgtta tggtttctac tatgactgat gtaaatatga acaataattt
     7201 aatatagata tgttttaata tagactttac tttaatgaaa atttataaaa tattttaaat
     7261 atattattca aaaactctca ttatatgtta aaataactta tgtatcaaca aattaagagg
     7321 gaggatttga gatatgaaaa aaatcatatt agctttaaca acttttttat tagcaatatc
     7381 tttaacagca tgttcaagtg caaaaccaga agatacaatt gatagttttt ttaacagtgc
     7441 gaaaaagttt gactttgaag gcatgaataa ggtaatggaa aataatgacg aaaaatataa
     7501 ggatatatta aaggaattag atacaaaaga cccaaatgcc caatatgttt tagattatct
     7561 aaaacagaat gcatctaaaa tcacgtatac aataaaagac agcgaggtta aaggtgataa
     7621 ggctacaatc aaagtagaat gtaaatttat agattcaaca ccattacttc aagaaatagt
     7681 agctgaggca tttacaaaga tgattggtat gagtttttca ggacaagact taactgatga
     7741 gaaaacaact gaaatgttag tatcaattat gaaagaaaaa caaaaaagcg ttaaagagac
     7801 ttatgttaca aaaactgtag agtttgaatg ttctaaaaag gataataaat ggataataag
     7861 ttcagtaaat gatgcagtag ctgatgtatt gttatctaat cttgttacag caggacaaga
     7921 attttctaac tctatgaata cacttgaata atattgttta ggtgtagtaa agtaataaat
     7981 atatgattat ttttataaat aaacatataa atatttatga aggataccat ttttggtatc
     8041 ctttttatta atataatgaa atacatggtt aatttctata ttgtcaagaa actatgatat
     8101 atgttataag tctatactat ttaaaataaa cttataacat atatttttta taatatagtg
     8161 catgaaaaat ttatttaact aattttagat atttattgac aactgattca gccaagcatt
     8221 ttgatgaatc aacaatattt attgaaggat atgatttttc taaaactaca tttaaatcag
     8281 tacaagcaat tactatattt tctatagatt catttttaac atcttcgata agtttattcc
     8341 aaatatcaat attgtgtgga ttttctttat ccatttttat attttgaata agattgttta
     8401 attttatttg ccattcatct ttaaatataa attcatgtcc attatgtatt ataccattct
     8461 ggtaaattgt agactcaaaa gttgaactag tcgaaaaaag agttactttt tgtgagatag
     8521 taggtaattt tttaactgtt tcttctacaa tatttaatat tggtatatta atagactctt
     8581 ttaattcttt aaagtatata tgtgctgaat tgcatggcat tgcaataaaa tttacaccag
     8641 ttgattcaag cttttgtaat ccatcaatta tagtttcttt cataagttca tgatttattg
     8701 gacggtcaat ataaaatggg gtaggtaatg aatatatcat catctttgga aattcatcat
     8761 catattttgc tccatattga gattgacact catcaataat taaatcaaca aaaggggctg
     8821 ttgaccttgg acccattcca gccaaaatac caattaattt ttcattcata aaaattatct
     8881 cctttatata taaatatatt tatgtataaa ataaaaatct ataaaagcat aaaattatat
     8941 tttataatag attatattgt acacttgtat aatataaata taaagtgatt ttttagatta
     9001 tatattttaa tatactttct tatataaaaa ttattttaaa tcaagattat ctagtatttt
     9061 taaaaatatt tttacagcag tatccaagtc atctacagaa acactttcat taggattatg
     9121 acttacgccc ccagcacatc ttataaatac cataccaata tcagttatat tatccatttc
     9181 ctgagcatca tggccagcac cactataaat ataaaaagga ttaagattta aatctataaa
     9241 acttttttct atgatttttg ttattttatt agaacatggt acaggaacat tttcaaaagc
     9301 aagttcactt gtataattaa gttttctatt ttcacatata tgtgatattt cattaaatat
     9361 cttttctaca gaattatcaa gaatttcttg tgaacaagag cgtacatcga gtgtaaattc
     9421 gattattcta tataaaatgg ctaaatagct ggatttaagt aaaaaaaata gactttatca
     9481 ttgttttgcc acccatttgc caccgtaatt tttttcggtg gcaaattatc taacaagatt
     9541 ttctaaaata tctattgttt cactttccat tttacttgta acatgtgaat atgtgtccat
     9601 agtagttgat aattgactat gtcctaatct ttgttgtata tattttatat tagctccatt
     9661 ttctaataat aatgtagcat gtgtatgtct taaacaatgg aagttgaagt caaggtttaa
     9721 ttttttgtta attgttctca cacaagcatc aatgttgtta tgatttacaa atgagccatc
     9781 tttttttcta caaacccaat catactcagt ttctgtatac cattttccaa gtttaatttt
     9841 ctgctttttt tggtttaatt tttcttcttt taatacttta gataaagtat cacctattct
     9901 aatatctctt atggatgttt ttgttttagg tgaagttaat tcaaactctg aaacctttct
     9961 ctttattaaa ttttttctaa ctttgattat gttattatct aaatcgatat tgtcccaaca
    10021 aagacctaat atctctcctt ttctcattcc tgtatgaaaa cctataagta gaggaatata
    10081 gatatttgta tttttaggat atatctctag aattttatta aattcatcta atgttatagt
    10141 tttgttttct gaatcttttt ttgtatctat aatatttttg ggtatgttgg tgtattgagc
    10201 aggattttct ttaataagct tgtaaggata aacagcagat tttaaagcag agtttaatac
    10261 accatagatt gctttcaaat tacctcttgt atagcgtctt tcttctccgt tttgagtata
    10321 tgtttctttt gttttattgt tcaggaactc ttgaataata gctggattta tagattttaa
    10381 tttatatttg ccaagttcag gctctatatg gtttttaatt aaatttctat aatttacttg
    10441 agtattatat ttacaattaa gaagtacata ttctttatac caaaagtcta aataattaga
    10501 taaactcata tttgtttcat caaatactat accagcattt tcatattcat ttattgcatc
    10561 tcttaaagct ttttcagctt cctttttagt ttctccacca actttttcta ctttttttct
    10621 cttaccattt acaatacctg catcaaaata gtaataccat ttcttacctc tttttcttac
    10681 tccacccttc ataaaaattt ctcctctcaa aattaaataa tg
//
LOCUS       DACTZW010000116        10632 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.117, whole genome shotgun sequence.
ACCESSION   DACTZW010000116 DACTZW010000000
VERSION     DACTZW010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10632
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.117"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(164..1369)
                     /locus_tag="JAM15_17160"
     CDS             complement(164..1369)
                     /locus_tag="JAM15_17160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014063556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAT6799977.1"
                     /translation="MNTLRKQLVKEIISDGEFIKSGDISSYLRDMFKDILQEMLEQEM
                     ALELGYEKGDSHNKNTTNRRNGYSKKTVKSQFGDLQLDVPRDRDNDFNPVVVPKNIRD
                     ISGIEEKIISLYARGMSTRDIHDQILDLYGIEISADQVSNITNVIIQRAKEWQNRPLE
                     QVYPFVFMDAIHYKVRDDGKIKNKAAYVVLGVNKDGFKDILGIWIGENETSKFWYSVL
                     TDLKNRGVKDVLIFSVDGLNGFKEAIAASYPNSIIQKCIIHQIRNTFKYVSYKDSKAL
                     ISDFKSVYKAVNEQEASSALDKIDEKWGKQYPSAIKIWRNNWDVIAPFFSFPEEIRTI
                     MYTTNIIEGLNRQFRKVTKTKSTFPSDDSLLKILFLASENVMKKWTMRYRNWDSIYNQ
                     LSIFFDNRI"
     gene            complement(1490..2416)
                     /locus_tag="JAM15_17165"
     CDS             complement(1490..2416)
                     /locus_tag="JAM15_17165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HAT6799978.1"
                     /translation="MSKENKNVRIAVVQASPVIMDLEKTVEKALGLIKEAGRKGANIV
                     VFPEAFIPAYPRGLSFGFVVGSRTMEGREDWKRYYDNSVPVPSATTDLLGKAAQEAGV
                     YLSMGITERDGNDINCTLYCTNLFFSPEGKLIGKHRKLKPTGTERCIWGEGDGSTLTV
                     VDTPYGKMGSLICWENYMPLARTALYAKGVKLYIAPTADSREEWQATMKHIALEGRCF
                     VIGCNQYVEKNMYPTDLNYYKELDAEPEIMCPGGSCIVDPFGKYVAGPIFNKEEMLIA
                     DLDLEKIVLSRLDFDSEGHYSRPDVFELIVHE"
     gene            2802..4406
                     /locus_tag="JAM15_17170"
     CDS             2802..4406
                     /locus_tag="JAM15_17170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HAT6799979.1"
                     /translation="MKAKIYYNGNIITMEDSICGDAILIKDKIIKKIGTKEEVFALKN
                     KDTEIIDLQGKTLMPSFIDSHSHLIAFATTLKLVPLEDATSFKDIVKKIQDFKESNNI
                     KKGDWIIGFSYDNNFLEENKHPDKSVLDSASSENPILISHASGHMGVANTLGLKQLGV
                     TNETRDPEGGHIGRVEGGEEPNGYLEENAFFNVASKIKQPSSNEIFNSIEKAQNIYLS
                     YGITTAQEGLMEENQFNILKAMANQNKLKMDVVGYVNLKKSKSVVDNNREFIKKYINR
                     FKIGGYKIFLDGSPQGKTAWLSRPYENSDDGYCGYPIYKDEEVEKFIDISLKEKMQLL
                     THCNGDAAADQLIDAFEKVLNLKEQSSENNIRPVMIHAQTVREDQIDDMKVINMIPSY
                     FVAHTYYWGDIHIKNLGEDRAFKISPLKTTIEKGLIYTLHQDTPVIAPNMLETVWCAV
                     NRITKKGIQIGENEKISPLDALKGVTINAAYQYFEEDKKGSIKEGKLANLIILDENPL
                     TIDPMKIKDIKVLQTIREGEVLYSLK"
     gene            5223..6494
                     /gene="serS"
                     /locus_tag="JAM15_17175"
     CDS             5223..6494
                     /gene="serS"
                     /locus_tag="JAM15_17175"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006441208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HAT6799980.1"
                     /translation="MLDIKRIRENLDCIKKAMERRGEKDFNLDEVVKLDDERRKILQE
                     VEVMKHKLNTASKNIPNLIKEGKDVENEKIKLKELSDKIKVIDQNLKEVEDKMEYLLM
                     RIPNVPHPEVPQGETDEDNVEVRTWGKTTTFDFESKAHWEIGTELGILDFETASKITG
                     SRFTLYKGLGARLERALLNFYLDTNTKVNGYTEVIPPFMANRNSFLGTGQLPKFEEDM
                     FKIEGLDYFMIPTSEVPLTNIHANEILKFEQLPINYTAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVEMVKIVAPEESYNELEKLTNNAETMLQLLNLPYRVVKICTGDLGFTASFK
                     YDVEVWMPSYNRYVEISSCSNCEDFQARRAGIRFKRDKDSKAEYVHTLNGSGLAIGRS
                     VAAILENYQQEDGSVVVPEVLRPYMGVSVIK"
     gene            6862..8367
                     /locus_tag="JAM15_17180"
     CDS             6862..8367
                     /locus_tag="JAM15_17180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HAT6799981.1"
                     /translation="MKIQNTEWGYIEWKHTYDENNPKQAMNIYIAVTMPGKKHFNHVH
                     YGQEQMIYILEGEGLYIINGVWKPFYQGMIFYIESGSTHETINTGDREIKELIVSNNV
                     DDVGESEVIDINPNNYLKKTLINYSESTLNLYAAVESIRGQFIDPFKIPLIIYDDSWN
                     IVLKNPYFPLFCFEKCNPMKFPQNCDCMNQKSSNQFVCEYGITIYNIPILYKSNSIGV
                     IRGGYVLLSDLNLDTEHNNLYDIPEGAARSIKRLLKQISKNIINFCSFNDIRKDLQEK
                     EKTIARTYHYGEQLEMNLKVAQDMVTNLRINHHFLFNTLNSMASIALDDGSYDLYSAI
                     IDLSRMFRYTMRSDLRFVELESEILYIKNYLNLQKLRYGDALKVKYLIPEKLYNLSVP
                     FNFIQPIVENAFTHGFRDIDTEKRIEIIARLDSQYAIIEIHNNGTILDGNNIDKIKAG
                     IRSNNGHGLSLIYTKFTSAYGNNFDMDIKSSDNEGTYIMIKIPIENYKEYV"
     gene            8481..9179
                     /locus_tag="JAM15_17185"
     CDS             8481..9179
                     /locus_tag="JAM15_17185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAT6799982.1"
                     /translation="MRRALIIDDEEAVLKIITHFIEMKDMPIKIVGKATSGDEAVDKI
                     IGLEPDIVFIDIQMPIYNGLEVIEKTSHLSKKINFVVITAFNYFEYAQKALRLNVKDI
                     LLKPLDMKEFTKSVEKIIGYQYTNNDLLNEILEYINLNYSNDLKLNDCARLFLTNPSN
                     ISRIFKSNLNTTFISYLNHIRIEKSIELLENTTKSINEIAEIVGYNSLNNFYKNFKIE
                     KGMTPKVYKLNTKN"
     gene            9464..10552
                     /locus_tag="JAM15_17190"
     CDS             9464..10552
                     /locus_tag="JAM15_17190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799983.1"
                     /translation="MSDKVNMKNIICIAGAYLATAIGSGFATGQEILQFFASQGYMGL
                     IGALISMVLFSFLGAEVITRGRELKLKEPTRIYTFYCGKILGKFYEWFSPIFLFGILI
                     VMISGAGSTLTEYYGINPYLGRVLMAVATLITVSMGLEKLVSILGRIGPVIAVFTIAV
                     GLISLFKHFDGLSMVGEAMKNIEVTKASESPIVSGVIYNTLNIIVMIVFLTGMGASIE
                     SKKDAFWGGLLGGIVFMTAGIVMYLAMISDIGNLYMKEIPSLYLADNISPIVGVCFSV
                     ALILGIYTTAVPLLWSVTNRIVEDEHPKFKLVTTVIAILACIGGFLPFGKLVNILYPY
                     TGYMGLLILVCMVYKAITCRKKSTQSQE"
BASE COUNT         4112 a         1262 c         1612 g         3646 t
ORIGIN      
        1 gataatttct actttatagc aacaattatt tatttactat taatatttcc caatatatga
       61 attttattct aataaattgt aaaaaatata tactgggata tttttaaata tttttgtaaa
      121 ccatatatat tatggcaaat ttttagaata tgatttttta aaattatatt ctattatcaa
      181 agaatataga taactgatta tatatactat cccagtttct atatctcata gtccattttt
      241 tcatcacatt ttcacttgct aagaacaata tttttaatag tgaatcgtct gatggaaaag
      301 tggactttgt ttttgtgact tttctaaact gtctattaag tccttcaatt atatttgtag
      361 tgtacattat agtccttatt tcttcaggaa aactaaaaaa tggtgctata acatcccagt
      421 tatttctcca aattttaatt gccgaaggat actgtttacc ccatttttca tctattttat
      481 ctaaagccga tgaggcttct tgttcattaa ctgctttata tacagattta aaatcactta
      541 ttaatgcttt tgaatctttg tatgaaacat atttaaaagt atttcttatc tgatggatta
      601 tacatttttg tattatagaa ttaggataac ttgcggctat cgcctctttg aagccattta
      661 atccatcaac actaaaaatt agtacatctt taacacctct attttttaaa tcggttaaaa
      721 cactatacca aaactttgaa gtttcgtttt cacctatcca tattcctaaa atatctttga
      781 aaccatcctt atttactcct agaactacat atgcagcttt attttttatt tttccatcat
      841 ctcttacttt gtaatgaatt gcatccataa atacaaaagg ataaacttgt tcaagaggtc
      901 tattttgcca ctctttagct ctttgaatta taacatttgt tatattactt acttgatcag
      961 ctgaaatttc tataccgtat aaatctaata tctggtcatg tatatctctt gttgacatac
     1021 ctcttgcata aagtgatatt attttttctt cgattcctga aatatctcta atatttttag
     1081 gaacgactac tgggttaaag tcattatctc tgtctcttgg aacgtctagt tgtaaatctc
     1141 caaattgtga ttttacagtt tttttgctat atccatttct tctattagtt gtattcttgt
     1201 tatggctgtc gcccttttca taacctagct ctaatgccat ttcttgttct aacatctctt
     1261 gtagtatatc tttgaacata tctcttagat agctacttat atctccagat tttataaatt
     1321 ctccatctga tataatttct ttgactaatt gttttcttaa agtattcata aaaaatctcc
     1381 tttacgacat ttgattatat ttaaatcatt gccataaaga agatttttat taaccttgaa
     1441 gcacaaatta ttttacatta cctctcatgt agatgtttgt gtaaaaagat tattcatgaa
     1501 caattaattc aaatacatct ggtcttgaat agtgaccttc tgaatcaaaa tctagtcgac
     1561 taagtactat tttttctagg tctaaatcag ctattagcat ttcttcttta ttgaaaatag
     1621 gacctgctac atattttcca aaagggtcaa ctatacaact tcctcctgga cacataattt
     1681 ctggttctgc atctagctcc ttatagtagt taaggtcagt tggatacata tttttttcaa
     1741 catattgatt gcatccaatt acaaaacatc ttccttctaa agcaatatgc ttcatagttg
     1801 cttgccactc ttctcttgaa tctgcagtag gggctatgta aagttttaca cccttagcat
     1861 aaagagctgt tctagctaat ggcatataat tttcccaaca aatcaacgaa cccatttttc
     1921 catatggagt atcaactact gtaagagtac ttccatctcc ttctccccaa atacatcttt
     1981 ctgttcctgt aggtttaagt tttctgtgtt taccaattag cttaccttct ggagagaaaa
     2041 ataagtttgt gcaataaagg gtacaattta tatcattacc atctctttct gttataccca
     2101 ttgatagata tactcctgct tcttgtgctg cttttcctaa taaatctgtt gtagcactag
     2161 gaactggtac agaattatca tagtatcttt tccaatcttc tctaccttcc attgttctac
     2221 ttccaacaac aaatccaaat gaaagacctc ttggatatgc aggtatgaat gcttcaggga
     2281 aaactacgat atttgcccct tttctaccag cttctttaat taatcctaat gctttttcaa
     2341 cagttttttc taaatccatt atgactggtg acgcctggac aacagcaatt cttacatttt
     2401 tattttcctt gctcataaaa aacctcctaa aaaatattta aattttttgc attgaataga
     2461 ttacatgaga tgttatttga gaactaagat acttatattg tgaataataa tgtaactgta
     2521 tatttaaaat aatacatcat gatttaaaaa attacaattg tacagatata attgagttta
     2581 gatatttaaa tttaacaact tataatattt tttcaattag tataaagcct attaatttgt
     2641 cttatttaca atgaatagta tttacttctt ggcaaacaat aattaaaaat aaaactttta
     2701 tatgattaaa ctctaaagaa aaagtttata aagaagataa tataattaag cagaaaataa
     2761 tgaaaaaaat ttattaaagt agacaacgta aggagaattt tatgaaagca aaaatttatt
     2821 acaatggaaa tatcatcaca atggaagatt caatatgtgg agatgctatt cttataaaag
     2881 acaaaataat aaaaaagata ggaacaaaag aagaagtatt tgctttgaaa aataaagata
     2941 cagaaattat agatttacaa ggtaagacat tgatgccatc ttttatagat tcacatagtc
     3001 acttgatagc ttttgctact actctaaagc tagttccttt agaagatgca accagtttta
     3061 aagacatagt aaaaaaaata caggatttca aagagtcgaa taatataaaa aaaggagact
     3121 ggataattgg attttcatat gataataatt ttttagaaga aaataagcat ccagataaga
     3181 gtgtacttga tagtgcatct tcagaaaatc caatactaat ttcacatgct tctggtcata
     3241 tgggagttgc aaatacattg gggttaaaac agcttggtgt taccaatgaa acacgtgacc
     3301 cagaaggtgg acatataggt agagtagaag gcggtgaaga accaaatgga tatttagaag
     3361 aaaatgcatt ttttaatgta gcatctaaaa taaaacaacc atcatcaaat gagattttta
     3421 attcaattga aaaagcacag aacatatatc taagctatgg tattacaaca gctcaagaag
     3481 gtttaatgga agaaaatcaa tttaacattt taaaagcaat ggcaaatcaa aataaattaa
     3541 aaatggatgt tgtaggatat gtaaatttga aaaaaagtaa gtctgtagta gataataata
     3601 gggagtttat aaaaaaatat ataaatagat ttaaaatagg aggttataag attttcttag
     3661 atggttctcc acaaggtaag acagcatggt tgagtagacc atatgaaaat tcagatgatg
     3721 gttattgtgg atatcctata tacaaagatg aagaagtaga aaagtttata gatatttcac
     3781 taaaagaaaa gatgcaactc ttaactcatt gtaatggaga tgcagcagca gaccagttga
     3841 tagatgcgtt tgagaaagtt ttaaacttaa aagagcaaag tagtgaaaat aatataagac
     3901 cagttatgat acatgctcaa acagtaagag aagaccagat tgatgatatg aaagtaataa
     3961 atatgatacc ttcatacttt gtagctcaca catattattg gggtgatatt catatcaaaa
     4021 accttggaga agatagagcg tttaagatta gcccacttaa aacaactata gaaaagggat
     4081 taatttacac tcttcatcag gatacaccag taatagcacc taatatgctg gaaacagtat
     4141 ggtgtgctgt aaatagaatt acaaaaaaag gtatacaaat aggagagaat gaaaagataa
     4201 gcccattaga tgctttaaag ggtgttacta taaatgcagc atatcaatat tttgaagaag
     4261 ataaaaaagg ttcaattaaa gaaggtaaat tagctaattt gataatatta gatgaaaacc
     4321 cacttacaat cgaccctatg aaaataaaag atattaaagt attgcagact ataagagaag
     4381 gagaagtatt gtattctttg aagtagatga aagttagata ttttataatc tataaaaaat
     4441 agttttatat aataagttag gtagaattaa ataagattac agttaaatca acaattatat
     4501 tttttattaa attttaatta ttgtattgaa gatttataag tataatttta ttgattctac
     4561 ctttttaaat aactgtcgat ttattaaagt tatctatgta ctatattaaa caattaagta
     4621 gttattaatt gcacttatta gtttattaaa aaactatgta tattactttg cagtaagact
     4681 ttggaactaa atctataata gcaaatttaa atttattaaa tagattacct tataacattt
     4741 catataaaat atattgtgaa tctgagaaaa ttactatttt tctttgagta ttttttataa
     4801 gcagttctaa aagattcaat ttcataccta ttacttgaag cattcattaa aataattcta
     4861 atttaaaaaa taattctatc caaataatag atatatagga ctatgttata atataaaaaa
     4921 atttatataa aagttaataa ctatacaaga ttgataaaga aaaagtcaaa atagataatt
     4981 gattagcaaa atagatataa ttataatgaa gttaaatcta gcaatattct cctaaaatta
     5041 aatttcattt atttaattaa atataatttg acaatggaca aaaaagtgag taaaatataa
     5101 ataaaataaa aataacaggt tcggataaag aaaaaggttt cttaacctca agcataaagt
     5161 atattatcta agttatttga gattaagaga taaatccaat cttaggtact gaggaggaaa
     5221 aaatgcttga tataaaaaga ataagagaaa atttagattg tataaaaaaa gcaatggaaa
     5281 gaaggggcga aaaagacttt aaccttgatg aagtagttaa gttagatgat gaaagaagaa
     5341 agattcttca agaagttgaa gttatgaaac ataaattaaa tacagcatct aaaaatatac
     5401 caaatcttat aaaagaaggt aaagatgtag aaaatgaaaa gattaaacta aaagagttat
     5461 ctgataaaat taaggtaata gaccaaaatc ttaaagaagt agaagataag atggaatacc
     5521 tattaatgag aataccaaat gtaccacatc cagaagtacc acaaggtgaa actgatgaag
     5581 ataatgttga ggtaagaact tggggaaaga ctactacctt tgattttgaa tctaaggctc
     5641 attgggaaat tggaacagaa ttaggtatac ttgattttga aacagcgagt aaaataactg
     5701 gttcaagatt cactctttac aaaggattgg gtgctagatt agagagagca ttattaaatt
     5761 tttacttaga cacgaataca aaagtaaatg gatatacaga agtcattcca ccatttatgg
     5821 caaatagaaa tagtttttta ggtacaggac agttacctaa gtttgaagaa gatatgttta
     5881 aaatagaagg tctggactat tttatgattc caacatcaga agttccttta actaatatac
     5941 atgctaatga aatacttaaa tttgaacaat taccaataaa ttatacagct tatactccat
     6001 gttttaggtc agaagctggt tctgctggaa gagatacaag aggtttagta agacagcatc
     6061 agtttaacaa agtagaaatg gttaaaatag ttgcaccaga agaatcttac aatgagttag
     6121 aaaagcttac taacaatgcg gaaactatgc tacaattatt gaatctgcct tatagagtag
     6181 taaagatatg tacaggtgat ttaggattta cggcttcttt taaatatgat gtagaagttt
     6241 ggatgccaag ttacaatagg tatgttgaga tttcatcttg ttcaaactgc gaagatttcc
     6301 aagctagaag agcaggaata agatttaaaa gagataaaga ttctaaagct gaatatgtac
     6361 acacattaaa tggctctggg ttagctattg gaagaagtgt tgcagctata ttagaaaatt
     6421 atcaacaaga agatggttct gtggttgttc ctgaagtttt aagaccatat atgggagttt
     6481 ctgttattaa ataagagtta aattatgtat ttttaagcaa tacaataata tagaagtaat
     6541 aaaaaataat taatataaaa gtgatacaat aatatagaag taataaaaaa atagttaata
     6601 taaaagtgat acaataatat agaagtaata aaaaatagtt aatataaaag tgatacaata
     6661 atatagaagt aataaaaaaa tagttaatat aaaagtgata caataataat agaagtaata
     6721 aaaaaaaata attaatataa aaatgtgtac aaactaatga atattgatat agtaagctat
     6781 catatgaaag agtatgtaca catttttttt actaattttt cacaatatga acataaataa
     6841 tttacaggaa aggaatcttt tatgaaaatt caaaatactg agtggggata tattgaatgg
     6901 aaacatactt atgatgaaaa taatccaaaa caagctatga atatatacat tgcagtaact
     6961 atgcctggta agaaacattt taatcatgtt cattatggtc aagagcagat gatatatatt
     7021 ttagagggag agggtttgta tattataaat ggagtttgga agccatttta tcaaggtatg
     7081 attttttata tagaatctgg tagcacacat gaaactataa atacaggcga tagagaaata
     7141 aaagaactta ttgtttcaaa taatgtagat gatgtaggag agagtgaagt tatagatatt
     7201 aatcctaata attatttaaa gaagaccttg ataaattata gtgaaagtac attaaatttg
     7261 tatgcagcag tagaatcaat tcgtggtcaa tttatagacc cgtttaaaat tccattaatt
     7321 atatatgatg attcatggaa tatagtttta aaaaaccctt attttccact tttttgtttt
     7381 gaaaaatgta atcctatgaa atttcctcaa aattgtgatt gtatgaatca aaaaagtagc
     7441 aatcaatttg tatgtgaata tgggataact atatataata taccaatact gtacaaaagc
     7501 aatagcatag gtgttataag aggagggtat gtactattat ctgatttaaa tttagataca
     7561 gagcataata atttatatga tattccagag ggagctgcta gaagtataaa acgcctcttg
     7621 aaacaaatat ctaaaaatat aataaatttt tgctctttta atgatataag aaaggattta
     7681 caagaaaaag agaagactat agcaagaaca tatcattatg gagagcaact tgaaatgaat
     7741 ttaaaagtag ctcaagatat ggttactaat ttaagaataa atcatcactt tttatttaat
     7801 acattaaatt caatggcaag catagcacta gatgatggta gttatgattt gtatagtgca
     7861 ataatagatt tatcaagaat gtttagatat acaatgaggt ctgatttaag atttgtagaa
     7921 ttagaatctg aaatattata cattaaaaat tatttgaatt tacagaaatt acgttatgga
     7981 gatgcactta aagtaaaata tcttattcca gagaagttat ataacctttc tgtgcctttt
     8041 aactttattc aacctattgt agagaatgca tttacacatg gatttagaga tattgacaca
     8101 gaaaagcgaa ttgaaataat tgcaagatta gattctcagt atgctattat agagattcat
     8161 aataatggaa ctatcttaga tggaaataat atagacaaaa taaaggcagg tattcgtagt
     8221 aataatggtc atggtttgtc tttaatatat acaaaattca catctgctta tggaaataat
     8281 tttgatatgg atataaagtc gagtgataat gaaggaactt acataatgat taaaattcct
     8341 attgaaaatt ataaggagta tgtatagaac ttgtgaaaaa ttaataagtt ttataaatgt
     8401 taagaaatat attagatgtt tttatgttgt tttatatatc ttactttttt atattattaa
     8461 gctaaaaggg aggtattctc atgagaagag cactaataat agatgatgaa gaagctgttc
     8521 taaaaataat aacacatttt atagaaatga aagatatgcc aataaaaatt gttggtaaag
     8581 caacatctgg tgatgaagca gtagataaaa tcattggttt agagccagac atagttttta
     8641 tagatattca aatgccaata tacaatgggt tagaagtaat agaaaaaaca tctcatttat
     8701 ctaaaaaaat aaactttgta gtaataactg catttaacta ttttgaatat gctcaaaaag
     8761 ctttgagatt aaatgtaaaa gatatactcc ttaaaccatt ggatatgaaa gaatttacta
     8821 agtctgtaga aaaaattatt ggatatcaat ataccaataa tgatttatta aatgagatac
     8881 tggaatatat aaatctaaac tatagcaatg acttaaagtt aaatgattgt gctagattat
     8941 ttttaaccaa tccatctaat atatctagga tttttaaaag taatttaaat acaactttta
     9001 tatcatatct aaatcatata agaatagaaa aatctattga attacttgaa aatactacaa
     9061 aaagtataaa tgagattgca gaaatagttg gatataatag cctaaataac ttttataaaa
     9121 actttaagat agaaaaagga atgactccaa aagtttataa actgaacact aaaaattgaa
     9181 attgataaat aaaaagtcaa tatagataat tgtttgagtg tgtctgaata agtatacttt
     9241 aattatgata aaaattaaag cgctttaaac atatttaata atattaaacc ttataaaagc
     9301 tgtacctatt tatataaaaa aatatatata aataaaaaga aaaagatata caaaataaaa
     9361 aaagtgaatt aaatactgtt tcaaaaagac agaattttca tttaattcac tgagagttta
     9421 tatttcttaa aggaaggtaa ctttataatg gaggtaattt aatatgtcag acaaagtgaa
     9481 tatgaaaaat attatctgta ttgcaggcgc ttatctagca acagcaattg gttctgggtt
     9541 tgctactggt caagaaattc tacaattttt tgcctcacaa gggtatatgg gtttaattgg
     9601 agcattaata tcaatggtat tgttttcatt tcttggtgct gaagttataa ctagaggtag
     9661 agaattaaaa cttaaagaac caacaagaat ttacactttt tattgtggga agattttagg
     9721 aaaattttac gaatggttta gtccaatatt tttatttggg attcttatag taatgatttc
     9781 aggtgcaggc tcaactttaa ctgaatacta tggtataaat ccttacttag gaagagtatt
     9841 gatggctgtt gctactttaa ttacagtgtc tatgggttta gaaaaattag taagcatact
     9901 tggacgtatt ggaccagtga tagcagtatt tacaattgct gttggattaa taagcttgtt
     9961 taagcatttt gatggtttat ctatggttgg agaagctatg aaaaatattg aagttacaaa
    10021 agcatcagaa agtccaatcg tttctggtgt aatatataat acattaaata ttattgtaat
    10081 gattgttttt ttaacaggaa tgggagcttc tattgaaagt aaaaaggatg ctttttgggg
    10141 aggtttatta ggtggaatag tgtttatgac tgctggtata gttatgtatt tggctatgat
    10201 ttcagatata ggaaatttgt atatgaaaga aataccatca ctttatttag cagataatat
    10261 atctcctatt gtaggtgtat gtttttcagt tgcattaata ttaggtatct atacaacagc
    10321 tgttccactt ttatggtctg taaccaatag aattgttgaa gatgaacatc ctaaatttaa
    10381 attggtaaca acagtaatag ctattttggc ttgtatagga ggttttttac cgtttggtaa
    10441 attagtaaac attttatatc catatacagg ttatatgggg cttttaattt tagtctgtat
    10501 ggtgtataaa gcaattacat gtagaaaaaa atcaacacaa agtcaggaat agagccactt
    10561 attaatagtt tttatttaaa gaaatttttt atataatccg aatttaaaaa gtcaaaatag
    10621 ttaaataaat tg
//
LOCUS       DACTZW010000117        10416 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.118, whole genome shotgun sequence.
ACCESSION   DACTZW010000117 DACTZW010000000
VERSION     DACTZW010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10416
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.118"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            139..756
                     /locus_tag="JAM15_17195"
     CDS             139..756
                     /locus_tag="JAM15_17195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HAT6799984.1"
                     /translation="MEIFAIGHSNYPYDKLINMIKKYDINCVVDIRETPYSKYNIQYN
                     KEVFNESLRNSGFVYIYMGKEFGAKRTNKDVYTQEGYADFEKVAKEDIFLNGIERLKK
                     GCQMGYRIVLLGAMQEPIRCHRSILVGKVLNKEGFDVKYIMHEGNLAYQEDIEESLLD
                     KYFSDRKQLSIDNLLGSALTREEMIQEGYKLANKEIGYRTEKLSK"
     gene            complement(913..1365)
                     /locus_tag="JAM15_17200"
     CDS             complement(913..1365)
                     /locus_tag="JAM15_17200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799985.1"
                     /translation="MVNLNANNLNVNMVYPISSTAPIRFRRYTVSYLENMENIYLTIA
                     TYFDTLGLGTLNIDKVYGQWAWFTDNIYDLNLFVFVGNYPYQIAKNRYDTFVNILPVA
                     ITSIVNGDRVFLTSNPCLLNSKITVRFISSHPTLNRTVNYGNIRDFIF"
     gene            1813..3171
                     /locus_tag="JAM15_17205"
     CDS             1813..3171
                     /locus_tag="JAM15_17205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012058627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HAT6799986.1"
                     /translation="MFIRKNVIKLAIPIMIEQTFVMLLGVFNTMMAGHIGEEAVSAVG
                     MVDSINNIFISVFAALSVGATVVVAQQIGKKDSEKVNETIKQALVSGVILSFTITILM
                     WVFRTGVINLFYGSAEELVKSNAKLYIEFTLFTYPFIATQQIANGILRGCGDVKKPMY
                     VTMFMNIVNVTLGYILIYGIDLNPLGINLQTPSYGITGAAISIAIARIIGCIVIIRAL
                     FKGNEFISMGKIFPFKIDVETQKSIFNIGIPAGVEQLLFNAGKLIVQVFIVTMGTSAI
                     ASNAIGMSIASIINVIGNALALSATTLVGQYIGRGDIKGAKSTLLYLTKFATICLFIV
                     GAIFIPIAPWISSMYTQNASVIDISTQLIRSDCLAMVIWPISFVLSAGLKGAGDTRYT
                     MMTAVIGMWIFRIFTGYVLGVVLEFGVLGIWIGMYTDWLVRGTLYCLRLRGTKWLKHK
                     VA"
     gene            3444..3824
                     /locus_tag="JAM15_17210"
     CDS             3444..3824
                     /locus_tag="JAM15_17210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015393264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAT6799987.1"
                     /translation="MINKIGKITLYVNNQEDAKLFWTEKLNFVVTYEKEMGPNMKWVE
                     VAPSKNEFTTFVLYDKNLMMKQNKEINVSHPSIILSTRDINGTYEQMANNEVEVGELM
                     EMPYGRMFSFKDQDGNDYLVREDK"
     gene            3949..4149
                     /locus_tag="JAM15_17215"
     CDS             3949..4149
                     /locus_tag="JAM15_17215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6799988.1"
                     /translation="MFKKMAVLKDIATKIGRKKAYELLEMVEGNDAFVAEVKIKKNGI
                     ESKKEEIMLKDNQKIILEYIEG"
     gene            4345..5073
                     /locus_tag="JAM15_17220"
     CDS             4345..5073
                     /locus_tag="JAM15_17220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAT6799989.1"
                     /translation="MLEIKNLSFNVESNNEELGIINDVSLSFERGKLIVITGPNGGGK
                     STIAKLIMGIEKATSGQIILDGEDITNLSITERAKKGIGYAFQQPPRIKGMTVENLLT
                     LAHGKPLSTDVCCQYLTDVGLCSKDYLNREVDNSLSGGEMKRIEIATLFARDLKVSIF
                     DEPEAGIDLWSFGKLNESFKKIHEESNQTIIIISHQERILELADEIIVLQDGSVKSHG
                     TKEAILPEIMCQVNSSCELMKDMN"
     gene            5095..6012
                     /locus_tag="JAM15_17225"
     CDS             5095..6012
                     /locus_tag="JAM15_17225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufD family Fe-S cluster assembly protein"
                     /protein_id="HAT6799990.1"
                     /translation="MNKIDLNLLEKVAELRGTPLGAYNIRKNGQGVERHSTENVTIIP
                     KTDKPGIDIIVKPNTKGENVHIPVIVTEAGVQDMVYNDFEIGENADVVIIAGCGIHNC
                     GCDDSEHNGIHRFFLRKGARLKYVEKHYGEGDGEGKRILNPVTIVNMDEDSYCEMETI
                     QIKGVDSTKREMDANLGKGAKIVVFEKLLTHGNQVAESNMKVILEGENSSAQVVSRTV
                     GQDNSKQKFNPCVIGDSLCSAHVQCDSIIMGNSQISAIPEIAANHPDALLVHEAAIGK
                     IAGDQILKMMTLGLTEEEAEQQILNCFLK"
     gene            6154..7338
                     /locus_tag="JAM15_17230"
     CDS             6154..7338
                     /locus_tag="JAM15_17230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HAT6799991.1"
                     /translation="MKNLLIRNGIIISPTDGIKFEKRDILVLHGKIYAIGLNLKEKIR
                     KEKLLTNKEFEIINADNMYISPGFIDVHAHCYKRKLPTGMDSDSIGIEKGSTVIFDAG
                     TAGPSNYYDFKKKYMDECKTEVYSFLNVTNEGLNILNESTSLDVINFDKVESVVEKNI
                     EKIKGIKVKASKFQSNESGIDIIKKSKQVAKKLNLPLVVYIGEYPSYIDEVMNILGKG
                     DVVTPVYGNSTNGILKESGTLRKSVINAKNRGVLFDVCHGVDQFDFKVFKKAIKQGLE
                     PDLISTDMHIKNMKDVNYSLLNVINKIMELGISLEKCIEKVTEYPTKIFDLHGNKGRI
                     KIGGEGDFTIFTMEECNDIIKDYNNNELVLNKKLRLQYTVKSWMKSSEVYRHGYENTI
                     IN"
     gene            7445..7633
                     /locus_tag="JAM15_17235"
     CDS             7445..7633
                     /locus_tag="JAM15_17235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HAT6799992.1"
                     /translation="MKAFVDKDVCVACGACIGTCPDVFSMSDEGHSVAIEGEIPADLQ
                     DLCKEAEEGCPVSAITVK"
     gene            7783..8433
                     /locus_tag="JAM15_17240"
     CDS             7783..8433
                     /locus_tag="JAM15_17240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAT6799993.1"
                     /translation="MKKNYEIVLFDLDGTLTDPKEGITKSIQYSLNSFGIKEDLENLD
                     QFIGPPLHDTFKEYYKFEDKKAKEAVEKYREYFADKGIFENKIYENMKEILEMLYKNG
                     KILLVATSKPTVFAETILRYFDIDRYFKYIAGSNLDGTRVNKNEVIQYVLDLCNVKDK
                     DKVIMVGDRKYDIIGAKKIGIDSIGVLYGYGSFEELSESEPTYIVENVESIKDILL"
     gene            8536..9474
                     /locus_tag="JAM15_17245"
     CDS             8536..9474
                     /locus_tag="JAM15_17245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAT6799994.1"
                     /translation="MKSILIMGGSDFIGSALAKRLIKCGYQIDILTNGKKEIDYNGFK
                     EHLICDRKVRKDMENIITGRKYDYIYDMTAYTKEDVSNLIDFISMDNLKKYIVLSAGA
                     VYKDSGRNIKEENEKGENENWGKYGLNKKEAEDFIINSPIPYIIIRPTYIYGENNNLY
                     REYYFFEKIEKNEKIPVPKGKQVSNQFIYIGDLVKVLESIMKNPHVREAYNVTNPQLI
                     SWDDLIYTCGEIIGKEPIIKYVDMEKVEFRERTYFPFRNIDFNLDINKLIEHGLYIPN
                     VLLKEGLTATYKWFSANKPKMHDRKMNKVESVMQIV"
     gene            9500..10351
                     /locus_tag="JAM15_17250"
     CDS             9500..10351
                     /locus_tag="JAM15_17250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HAT6799995.1"
                     /translation="MNSKIKYFLKFFILIFILIFIYSVAIEPSLLIVKKYNISENGAL
                     IKNDTIESKSESVKVVQISDTQIGSFYSTKNLKKVANKINTLNPDIIVFTGDLIDYSN
                     KNPSVDEITTILSSMNARLGKFSVFGNHDYMYKLPRYYRQIMKNSNFNLLVNENKKIK
                     LKDDKYINILGVDEILNGNPNIKYLESQIDNKSFNLLLAHEPDLVDMLSKDTMNLVLS
                     GHSHGGQIRLPIKGALVTPPYGRKYTKGFYDINGNHLYVSSGLGSTKLPFRFFNIPEI
                     IEFNIII"
BASE COUNT         4229 a          992 c         1847 g         3348 t
ORIGIN      
        1 taaggatata aagtaaaaaa atatacagta tcaagaaaaa aagatattgt gtatttaaag
       61 taatacttta tttaatttta agtaaatcgg gtatctacat atatagatac taatttcaaa
      121 gaataggagg gtatttatat ggaaatattc gcaataggac attcaaatta tccatatgat
      181 aagcttatta atatgataaa aaaatatgac ataaattgtg tagttgacat tagagaaact
      241 ccatattcta aatataatat tcaatacaat aaagaggtat ttaacgaatc tcttagaaat
      301 tccggatttg tatatatata catgggaaaa gaatttggag ctaaaagaac taataaagat
      361 gtatatacgc aagaaggcta tgcagatttt gagaaagtag caaaagaaga tattttttta
      421 aacggaatag aaagattaaa aaagggttgt caaatgggtt ataggatagt tttattagga
      481 gctatgcaag aacctataag atgtcataga agtattttgg tgggaaaagt attaaataaa
      541 gaaggtttcg atgtaaaata tataatgcat gaaggaaatt tggcatatca ggaagatata
      601 gaggaatcat tattggataa gtattttagt gatagaaagc aattgagtat tgacaactta
      661 ttagggagtg cattaacgag agaagaaatg atacaagaag gttataagct agctaataaa
      721 gaaataggat atagaactga gaaactaagt aaataaaaat ataaaagtag ataaaataca
      781 gtacttacct taagtaaaat aatattatga atttataata gctaggcatg atgtgccaat
      841 taaaaatatt ctagttattt aataatatca ttaaatttag ggtatttttt aatagcacat
      901 catgttgtag ttttaaaaaa taaaatctct aatattgcca taattaactg ttctattaag
      961 agtaggatga ctagatataa atctaactgt aatttttgaa tttaacaaac aaggatttga
     1021 agttaaaaat actctatctc cattgacaat agaagtaatg gctactggca aaatatttac
     1081 aaatgtatca tatctgtttt tagcaatttg ataaggataa tttcctacaa aaacaaatag
     1141 attcaaatca tatatattat cagtgaacca agcccactga ccataaactt tgtcaatatt
     1201 caatgtgcct aaaccaagtg tatcaaagta tgttgctata gttaaataaa tattttccat
     1261 gttttctaaa tatgaaacag tatatcttct gaaacgtatg ggtgctgtgg aagaaatagg
     1321 ataaaccata tttacattta gattatttgc atttaaatta accaaagtat cacatcctaa
     1381 aattagtcta taaaatacaa tatttaaatg gatgcgattt tgttacattt aaagtgtaat
     1441 attttatata ttgaaaaagt ggtaaaagtt tgaatgatta aataatatta taaaaaatat
     1501 ataaaatgta cttattgtta ttgctacacg atagtgatac aatattaacg aaatatagct
     1561 acttttaata ataactgaaa atatttatat taaattaata aatattttaa atgtggtatc
     1621 cataaaaaat aataaacata agataattat aaagatatac tgtgttcaag tgatattaaa
     1681 caagatttat attatttgaa aacagtatat tataatgcga acaatacaat tctaaacttt
     1741 gcattgtcaa tttacagttc gataaactaa ttaaaaatta aatttatata aagagggaaa
     1801 agaggaatag ggatgtttat aaggaaaaat gttataaagt tagcaattcc tataatgata
     1861 gagcagacgt ttgtcatgct tttaggagta tttaatacaa tgatggcagg tcatattggg
     1921 gaagaagctg tatctgcagt tggaatggtt gattcaataa acaatatatt tatatctgta
     1981 tttgctgcat tatctgttgg agctactgtc gttgtagctc aacaaatagg aaaaaaagat
     2041 agtgaaaagg taaatgaaac tattaagcag gctctagtgt ctggagtaat attatccttt
     2101 acaataacaa tattgatgtg ggtttttaga actggtgtaa ttaatttatt ttatggttca
     2161 gcagaagaat tggtaaaatc aaatgcaaaa ttatacatag agtttacatt atttacgtat
     2221 ccatttattg cgacacaaca aatagcaaat ggtattttaa gagggtgtgg agatgtaaag
     2281 aaacctatgt atgtgactat gtttatgaat atagtaaatg taacattagg atatatactt
     2341 atatatggta ttgatttaaa tcctctagga ataaatttgc aaacaccatc ctatggcata
     2401 acaggtgcag ctatatctat tgctatagct agaataattg gatgtatagt aattataaga
     2461 gctttattta aaggaaatga atttatatct atgggtaaaa tatttccatt taagattgat
     2521 gttgaaactc aaaagtctat atttaatata gggataccag ctggagttga acaactactt
     2581 tttaatgcag gtaaattgat tgttcaagta tttatagtta ctatgggaac atcagcaatt
     2641 gcatctaatg caataggaat gtcaattgca tccataataa atgtaattgg gaatgcttta
     2701 gctttgtctg ctacaacttt ggtgggacag tatataggac gtggagatat taaaggagct
     2761 aagagtactt tattatattt aactaaattt gcaacaattt gtttatttat agtaggagct
     2821 atatttatac caattgcacc ctggatttca agtatgtata ctcaaaatgc tagtgtaatt
     2881 gacatctcaa cacaattaat tcgaagtgat tgtttagcta tggtaatatg gcctatatcc
     2941 tttgtattat cagcagggct aaagggagcc ggtgatacta gatatacaat gatgactgca
     3001 gtaataggta tgtggatttt tagaattttt acaggttacg tattgggggt tgtattagaa
     3061 tttggagtgt taggaatttg gataggtatg tatactgatt ggcttgttag agggacttta
     3121 tattgtttaa gattaagagg aacaaagtgg ctaaaacaca aagttgcata gaatatatga
     3181 aatcactttt agatggataa ctctatttag aagtgatttt ttatgtagtt attatcataa
     3241 ttataagtat gatatataag gttattaaat tacataaata aaggctataa tagtatggat
     3301 attataaatt atatattgag cagaattaca taatttggcg ataaatatta gaaatatata
     3361 tctatagaaa ataatatata tgggtatatt attaaatata aaaaatatta ggtatttatt
     3421 taataataaa ggtgggtatt gttatgataa ataaaatagg aaaaataact ctctatgtaa
     3481 ataatcaaga ggatgcaaag ttgttttgga cagaaaaatt gaactttgta gtaacttatg
     3541 aaaaggaaat gggtccaaat atgaaatggg tggaagtagc accaagtaaa aatgaattta
     3601 caacatttgt gttgtatgat aaaaatctaa tgatgaagca aaacaaagag ataaatgtat
     3661 ctcatccatc aataatttta agtacaagag atattaatgg aacttatgaa caaatggcaa
     3721 ataacgaggt tgaagttggg gaattaatgg agatgccata tggaaggatg ttttctttta
     3781 aagaccaaga tggaaatgat tatttagtca gagaggataa ataattttac aaagtattaa
     3841 atttactcaa tatctgatat aattagagac aataattatt ataaactagt ctaggattag
     3901 aattatataa ttaaaaatta agtgtaaatt ttgagtagag gtgataaaat gtttaagaaa
     3961 atggcagtac taaaagatat agcaactaaa ataggtcgta aaaaagcgta tgaactatta
     4021 gaaatggttg aaggtaatga tgcctttgta gctgaggtaa agataaaaaa gaatggaata
     4081 gaatctaaaa aagaagaaat tatgttaaaa gataatcaaa aaataatatt agagtatata
     4141 gaaggttaaa ttttaaatac atataagttg atatactaaa tttctgagat gagtttacat
     4201 aaaactcatc ttttttactt ttcaataact ttgttttatt atttaatata cattttatct
     4261 gcttagagtt gctgatatat aaaaattact gatataataa aagaatggat attaatgtaa
     4321 tattttatag aaaagagggg tattatgctt gaaataaaaa atctttcctt taatgttgag
     4381 tctaacaatg aggaactagg aataataaat gatgttagcc tttcatttga gaggggaaaa
     4441 cttattgtta tcacaggtcc aaatggtgga ggaaaatcta caattgctaa gcttattatg
     4501 ggaattgaaa aagctacgag tggtcagata attttagatg gagaagatat aacaaatctt
     4561 agtattacag aaagagcaaa aaaaggaata ggatacgcat ttcaacaacc accaagaata
     4621 aaaggtatga cagttgaaaa tttacttaca cttgctcatg gaaaaccatt gtctactgat
     4681 gtatgttgcc aataccttac agatgttgga ttgtgttcaa aagactattt aaatcgtgaa
     4741 gttgataact ctctttctgg aggggaaatg aaaagaattg agatagcaac tctttttgct
     4801 agagatttaa aggtttctat atttgatgaa cctgaagcag ggatagacct ttggagcttt
     4861 ggaaaactca atgaaagttt taagaaaata catgaagagt ctaatcagac tataatcata
     4921 atttctcacc aagaaagaat attagagtta gctgatgaaa taattgttct acaagatggt
     4981 tcagtaaaaa gccatggaac aaaagaggct atattacctg aaatcatgtg tcaagttaat
     5041 tcaagttgtg aattaatgaa agacatgaat taattagaaa ggaaggcaaa ttaaatgaac
     5101 aaaatagatt taaatctttt agaaaaagtt gctgaacttc gtggaactcc attaggagca
     5161 tacaatatac gtaaaaatgg gcaaggagta gagagacatt caactgaaaa tgtaactata
     5221 attcctaaaa ctgataaacc tggaatagat attatagtaa agccaaatac aaaaggagaa
     5281 aatgtacata taccagtaat agtaacagag gctggtgtac aggatatggt atataatgat
     5341 tttgaaattg gagaaaatgc agatgttgtt ataattgctg ggtgtggtat acataactgt
     5401 ggttgtgatg atagtgaaca taatggtata catagatttt tcttacgtaa aggagctcgc
     5461 ctaaaatatg tagaaaaaca ttatggtgaa ggtgatggag aaggaaagag aattttaaat
     5521 ccagttacta ttgtcaatat ggatgaggat tcatattgtg aaatggaaac aattcaaatt
     5581 aagggtgtag attcaactaa aagagaaatg gatgcaaacc taggtaaagg agctaaaata
     5641 gttgtatttg agaaattatt aactcatggt aatcaagttg cagaatctaa tatgaaggtt
     5701 atcttagagg gtgaaaactc ttctgctcaa gtagtttctc gtacagttgg gcaagataat
     5761 tctaagcaaa agtttaatcc ttgtgttatt ggggattccc tttgttctgc acatgttcaa
     5821 tgtgattcaa taattatggg aaactctcaa attagtgcta tacctgaaat tgctgcaaat
     5881 catccagatg ctcttttagt acatgaagca gctattggaa agattgcagg agaccaaata
     5941 ctaaagatga tgacattagg tcttactgaa gaagaagccg agcaacaaat acttaattgc
     6001 ttcttaaagt aaattaaaga ttttatttaa tttaatatga ttaatatagt ataatatagt
     6061 gaataagtct aaaatatttt tatttttagg cttattttct ttatgtaaga aaagctatta
     6121 gagaaattat attgtaatta ggatgtggaa taaatgaaaa atttacttat aagaaatggg
     6181 ataataatat ctccaacaga tggtatcaaa tttgaaaaaa gagatatctt ggttttacat
     6241 gggaaaatat atgctattgg attgaacctt aaagagaaaa taagaaaaga aaaattactt
     6301 acaaataaag agttcgagat aataaatgcc gataatatgt atatttcccc aggatttata
     6361 gatgttcacg cccattgtta taagagaaaa ttacctacag gtatggattc tgattcaatt
     6421 ggaattgaaa aaggttctac agttatattt gatgcaggta cagctggtcc ttcaaactac
     6481 tatgatttta aaaaaaagta tatggatgag tgtaaaacag aagtatattc ttttttaaat
     6541 gttacaaatg agggactaaa tatattgaat gaatcaactt ctttagatgt tataaatttt
     6601 gacaaggttg agtcagttgt agaaaaaaat atagaaaaga taaagggtat aaaagtaaaa
     6661 gcgagtaaat ttcaatctaa tgaaagtggt atagatataa ttaagaaatc aaagcaagtt
     6721 gctaaaaaat taaatttacc cttagtggta tatataggag agtatccatc atatatagat
     6781 gaagtaatga atattttggg aaaaggagat gtggttacac cagtatatgg aaatagtaca
     6841 aatggaatcc ttaaagaatc tggcacatta agaaaatcag taataaatgc aaagaataga
     6901 ggagtattgt ttgatgtatg tcatggagtg gaccaatttg attttaaagt ttttaaaaaa
     6961 gcaataaagc aaggtttaga gcctgaccta ataagtactg atatgcatat aaaaaacatg
     7021 aaagacgtaa actattctct tttaaatgtt ataaataaaa ttatggaact tgggatatcc
     7081 ctagaaaagt gtatagaaaa agtaactgaa tacccaacaa agattttcga tttacatgga
     7141 aataaaggca gaataaagat tggtggagaa ggtgatttta caatattcac aatggaggag
     7201 tgtaatgata ttataaaaga ctacaataat aatgaacttg ttttaaataa aaaattaaga
     7261 ttgcaatata ctgtaaaatc atggatgaaa agcagtgaag tttatagaca tggatacgaa
     7321 aatactataa taaactaaac aatagtgata aaataataaa tatatgttta aattggtata
     7381 tattggataa atatctaagg aaacaacaat taaaaaataa taattttagg ggaggtattt
     7441 tagtatgaaa gcatttgttg ataaggatgt atgtgtagct tgtggagcat gtataggaac
     7501 atgtccagac gtttttagta tgagcgatga agggcattca gtagcaattg aaggagaaat
     7561 accagcagat ttacaagatt tatgtaaaga agccgaagaa ggatgtccag tttcagctat
     7621 aacagttaaa tagagctgtt taaatttatt tttaaaataa atatataaga tttaattggg
     7681 tacttaagct atagtattag aaatttctat tactatagct ttttaaaata gataaactta
     7741 atatgtaaga tattactttt tacaaatatg gaggactgaa atatgaaaaa aaattatgaa
     7801 atagtattat tcgatttaga tggaacactt acagacccta aagaaggaat aacaaagtct
     7861 attcagtatt ctttaaatag ctttggcata aaagaagatt tggaaaactt agaccaattt
     7921 ataggaccac cattacatga tactttcaag gagtattata aatttgaaga taaaaaagct
     7981 aaagaagctg ttgaaaagta tagagaatat tttgctgata aagggatatt tgaaaataaa
     8041 atttatgaga atatgaaaga gatattagaa atgctctata aaaatggtaa aatattatta
     8101 gtagcaactt ctaagccaac agtttttgca gaaactatac ttagatattt tgatatagat
     8161 agatatttta aatatatagc aggtagcaat cttgatggta caagagtgaa taaaaatgaa
     8221 gttatacaat atgtactaga cctatgtaat gtaaaagata aagataaagt tattatggtt
     8281 ggagatagaa agtatgacat aattggagct aaaaaaatag gtatagattc tattggagta
     8341 ttgtatgggt atggttcttt tgaagagctt agtgaaagtg aacctactta tattgtcgaa
     8401 aatgtagagt ctataaaaga tattttgtta taaatatctt ttatagacaa aaatattaca
     8461 aaatggtgtc gcatatttaa aaatatgata ttatagttaa ggaagtcatt taaaaaagag
     8521 gaggatgcac ttaaaatgaa atctatttta attatgggtg gaagcgactt cataggttct
     8581 gcacttgcta agcgcttgat taaatgtggg tatcaaattg atatacttac aaatggtaaa
     8641 aaggaaatag attataatgg ttttaaagaa catctaattt gtgatagaaa agttcgaaaa
     8701 gatatggaaa acattatcac aggaagaaaa tatgattaca tatatgatat gacagcatat
     8761 acaaaagaag atgtaagtaa tctgattgat tttataagca tggataactt aaaaaagtat
     8821 atagtattgt cagcaggagc agtatataaa gatagtggaa gaaatataaa agaagaaaat
     8881 gagaaaggtg aaaatgaaaa ctggggaaaa tatgggttaa ataaaaaaga ggctgaagat
     8941 tttattataa atagccctat accatatata attattagac caacttacat atatggtgaa
     9001 aataataatt tatatagaga gtattatttc tttgaaaaaa tagaaaaaaa tgaaaagata
     9061 ccagtaccaa aaggaaaaca agttagtaat caatttatat atattgggga tttggtaaag
     9121 gtattggaaa gcataatgaa aaatcctcat gtaagagagg cctataatgt gacaaatcca
     9181 cagttaattt cttgggatga ccttatatat acatgtggag aaattattgg caaagaacct
     9241 ataataaaat atgtagatat ggaaaaagta gagtttagag aaagaacgta tttcccattt
     9301 agaaatatag actttaatct tgatataaat aagcttattg aacatgggct ttatatacca
     9361 aacgtgttac taaaagaagg tcttacagca acatataaat ggttttcagc aaataagcca
     9421 aaaatgcatg acagaaaaat gaacaaagtt gagtctgtaa tgcaaatagt ttaaaaaaat
     9481 aaataagtag gtagatattt tgaactcaaa aattaagtat tttttaaaat tttttatctt
     9541 aatatttatt ttgattttta tatactcagt tgcgatagag ccgagtctat taattgtgaa
     9601 aaaatataat ataagtgaaa atggagcatt gataaaaaat gatacaattg agagtaaatc
     9661 tgaaagtgta aaagtagttc aaatttcaga tactcaaata ggtagttttt attcaactaa
     9721 gaatctcaaa aaagtagcta ataagattaa cactttgaat ccagatataa tagtatttac
     9781 tggtgattta attgattact ccaataaaaa tccaagtgta gatgaaatta caactatttt
     9841 atcaagtatg aatgctaggt tgggaaaatt ttcagtattt ggcaatcatg attatatgta
     9901 taaacttcct aggtattata ggcagattat gaaaaattcc aacttcaatc ttttagtaaa
     9961 tgaaaataaa aaaataaaat taaaagatga taaatatatt aatatattag gtgttgatga
    10021 aatattaaat ggaaatccta atataaaata tctggagagt cagatagata ataaaagttt
    10081 taatttattg ttagcacatg aaccagattt agtagatatg cttagtaaag atacaatgaa
    10141 tttagttcta tctgggcata gtcatggtgg tcaaataaga ttacctatta agggagcatt
    10201 agttactcct ccatatggaa ggaaatatac taaagggttt tatgatataa atggaaatca
    10261 tttatatgtg agttcgggtc ttggaagtac aaagttacca tttagatttt ttaatatacc
    10321 agagataata gaatttaata ttataatcta acataaaata tttagaaaat ataattttgc
    10381 tttttataat atgtagatgt atatactgta aaaatg
//
LOCUS       DACTZW010000118         9999 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.119, whole genome shotgun sequence.
ACCESSION   DACTZW010000118 DACTZW010000000
VERSION     DACTZW010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9999
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.119"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            358..1986
                     /gene="aspD"
                     /locus_tag="JAM15_17255"
     CDS             358..1986
                     /gene="aspD"
                     /locus_tag="JAM15_17255"
                     /EC_number="4.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 4-decarboxylase"
                     /protein_id="HAT6799996.1"
                     /translation="MKNHTYKEIKNIYGKISPFEFKDKLIDIAKYTAKENNRELLDAG
                     RGNPNWTCSTAREAFFTFGHFAITETRSNWDLGHLAGMPQKKGIKERFFKFINENIDM
                     PGAYLARDIINFGINELGFDGDEFVHELADGIIGDNYPLPDRMLPHMEKIVHDYLVQE
                     MKYDISGKYGDVEIFAVEGATAAMCYIFDSLMANELLKKGDTIALMTPIFTPYLEIPN
                     LPRYDFKVVNINANEVDEKGAHTWQYTKKELEKLRDKSIKALFVVNPNNPASIAMDET
                     SCNNLIDVIENYNKDLMIISDDVYGTFVEDFSSLMSKLPYNTVGVYSYSKYFGVTGWR
                     LGTFALHKKNVFDKKINDLTGELKKSVDKRYSDMSLNPSSLSFMERVVADSRLVALNH
                     TAGLSTPQQVQMAFFSAFALIDKVDAYKKLNMSICHRRQKLLFEALELPINENKNNAA
                     YYTQFDIEEWAKLNYGEDLSKFISKTASPVDVLYKLANDYSVVLLSGNGFYGPEWSIR
                     ISLANLYDEAYTKIGKAIREILNGYIVEWQKIKK"
     gene            2107..3102
                     /locus_tag="JAM15_17260"
     CDS             2107..3102
                     /locus_tag="JAM15_17260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HAT6799997.1"
                     /translation="MSIKKKVAIVFTGGTISMTVDDKVGAAIPTLSGEQILSMVTNID
                     KVADVEVFNFDEIPGPHITPYRMMELKNYVNDLLARKDITGVVITHGTDSLEETAYFL
                     DLTIDNIKPVIVTGAMRSSSELGYDGSSNLSASVCTAVSKDAMGKGVLVVLNNEVLLA
                     SEATKTNTLSLNTFKSLTSGPLGIIDCNELVLTRDIVNRTIIDTDKVESKVALFKAYV
                     GENADFIRFAVDSGYKGIVIEAMGRGNIPPQMLSGVEYAREKGLPVVIVSRCHSGRVF
                     DSYGYFGSGRDLKNLGCIFGGDLPGQKARIKLILALGKTDNLDEIKDFFEKGIYC"
     gene            complement(3291..3674)
                     /locus_tag="JAM15_17265"
     CDS             complement(3291..3674)
                     /locus_tag="JAM15_17265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HAT6799998.1"
                     /translation="MLNKKLPDAELKIMKYIWNTGYKTVISKDVADEIEKTYAWKHTT
                     TITLLARLTKKGFFISQRIGKHVHYRVLIKEKEYLKIEGKRIFGGLHNNPLSELISKL
                     HDGEEITEEKIIEIGNWIKSWKDED"
     regulatory      3901..3998
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     repeat_region   4140..4762
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=4140..4168
                     /rpt_unit_seq="atttacattccatatagttaatataaaac"
     gene            complement(5565..6935)
                     /locus_tag="JAM15_17270"
     CDS             complement(5565..6935)
                     /locus_tag="JAM15_17270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp29"
                     /protein_id="HAT6799999.1"
                     /translation="MKLKKLLSLGLAVSMFAAGPISANALDTIYTIQGKDKYETAALI
                     ADEQNYTTAILINADSTMADGLSASGLAGATNAPIFLTKKNNIPNATLKRVEKAKKVY
                     IIGGESSIDKATETLLKDKGIEAKRLQGSDRIKTSYNVAKEINSINKVNKVILTNAFK
                     GEPDAMSAAPVAVRDKAAIVLTDGKSVPFNTTGVESYVIGGTSSMSDKLVNDTNSTRL
                     GGVDRYDTNKKIVNKFYNGAKEFYIASGTDLVYALVASPMAKNNPIVLVDIGSNKDIL
                     KNAAKVTGIGNLSDKIMLECENTINNISLPSSNKNIICGLKIDFDSKHIIWQDKGSYL
                     ECYDDNLEYYTEKYKDPTVPINIENTSTQNLDVTKLKVYGEANSTLYMGQYAKIKMDF
                     NSFGVLKPGEKCTIYLDIISLDPSRSMTLTFSYVGDKENYKYEQGLASRILFYNPDGE
                     DFFEYK"
     gene            7132..7374
                     /locus_tag="JAM15_17275"
     CDS             7132..7374
                     /locus_tag="JAM15_17275"
                     /inference="COORDINATES: protein motif:HMM:NF026008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800000.1"
                     /translation="MKGAYIYEYQISFYKKKDAEKHLIEIKSTINNNKFVAPKGMTFV
                     ERCYKYIDMNKNNWSPYTVTNTKSWVKNYIEPFLRI"
     gene            7482..7985
                     /locus_tag="JAM15_17280"
     CDS             7482..7985
                     /locus_tag="JAM15_17280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAT6800001.1"
                     /translation="MREAYRLREIQENSCDFIKLPSKEKYSTNEIYNRKEVLLLIEKL
                     LSNNIEIPILLMLLLGLRMGEATGLRWSDVDLDNNLINVNQILVYSNGKISFKEPKTP
                     KSKRALSAPKELIEKLKIEKLRQSKLKLQGILENKNNLVCLNTNLNPFLPSSLRKTFH
                     NFTKKII"
     gene            7991..8176
                     /locus_tag="JAM15_17285"
     CDS             7991..8176
                     /locus_tag="JAM15_17285"
                     /inference="COORDINATES: protein motif:HMM:NF012798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAT6800002.1"
                     /translation="MRIHDLRHTSATLLLLGGTNMKVVSERLGHTDIKITMNRYSHVL
                     KEMDKEASDNLSELLFK"
     gene            complement(8493..9161)
                     /locus_tag="JAM15_17290"
     CDS             complement(8493..9161)
                     /locus_tag="JAM15_17290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAT6800003.1"
                     /translation="METVTNNQSGVEIQLSLFEAIKDLLLINPIFLLGIILIGIFLVV
                     IFKKNSDIPKVKTSILSLAMYYYLCLTLSHIVGIPTFSEYIRLSQLGETFFNLNINLI
                     PFSDGFSLSFILNILLFVPLGFLCPLISKTFERLRNTFLIGFGLSLFIETIQLFTLHR
                     ATDIDDLLTNVIGTIIGYFCFKLIAKLRIVKLHSDDDSMEQDYTVCIPIAIIIVALIL
                     GFFS"
BASE COUNT         3607 a         1485 c         1318 g         3589 t
ORIGIN      
        1 tttaacatta ttaagattaa taaattaata aaatacatgt cttactaaac aacttcaata
       61 taaaagaaag ttttacttta tttttattca aaattagaaa actatacata tataataaaa
      121 tacaataaaa aaactaaggt gataattaaa ttgaatattt attttatata acaatcattt
      181 tttattaaaa ggtatttttt attttaacat atatttaata aggctaaata gagttattat
      241 tttaatttca tactttactt tttctataaa cctattataa ttaaagtata atcatttttg
      301 caacttgttt attttattat aaaaatgtga aacttattac ataaggagga atttaacatg
      361 aaaaatcata cttataaaga aattaaaaac atatatggaa aaataagccc ttttgaattt
      421 aaggacaaat taatagatat tgcaaaatac actgcaaaag aaaataacag agaattactt
      481 gatgcaggtc gtggaaatcc aaactggact tgttcaactg ctagagaagc cttttttact
      541 tttggtcatt tcgctattac tgaaactcgt tctaattggg atttaggtca tttggctgga
      601 atgcctcaaa aaaagggtat taaagaaaga ttttttaaat ttataaatga aaatatagat
      661 atgcctggag catatttagc tagagatatt ataaactttg gtataaatga acttggattt
      721 gatggagatg aatttgttca tgaactagct gatggaatta ttggtgataa ctatccactt
      781 ccagatagaa tgttacctca tatggaaaaa atagtacacg attacctagt tcaagaaatg
      841 aaatatgata tatcaggtaa atatggtgat gtagaaattt ttgctgttga aggtgctaca
      901 gctgctatgt gctatatatt tgattcatta atggcaaatg aacttctaaa aaaaggagat
      961 accatagcct taatgactcc aatatttaca ccttatcttg aaatacctaa ccttcctcgt
     1021 tacgacttta aagtggtaaa tataaatgct aatgaagttg atgaaaaagg tgctcacaca
     1081 tggcaatata caaaaaaaga attagagaaa cttcgtgaca agtctattaa agctttattc
     1141 gttgttaatc ctaataatcc tgcttctata gctatggatg aaacatcttg taataatcta
     1201 atagatgtaa ttgaaaatta taataaagat ttaatgataa tatcagatga tgtatatgga
     1261 acttttgtag aagatttttc atccttaatg tcaaaactac cttacaacac tgttggagta
     1321 tattcttatt caaaatattt tggagttaca ggatggagac ttggtacatt tgcccttcat
     1381 aagaaaaatg tttttgataa gaaaataaat gatttaactg gagaattaaa aaaatcagta
     1441 gataagcgtt acagtgatat gagtcttaac ccttctagcc tttcatttat ggaaagagtt
     1501 gttgctgata gcagacttgt tgctctcaac catactgctg gtctttctac tccacagcaa
     1561 gtacaaatgg catttttctc tgcttttgca ttgattgaca aagtagatgc ctacaaaaaa
     1621 ctcaatatga gtatctgcca tagacgtcaa aaactattat ttgaagcttt agagcttcca
     1681 attaatgaaa acaaaaacaa tgctgcatat tacactcaat ttgatattga agaatgggct
     1741 aaattaaact acggagaaga cttatctaaa tttataagta aaactgcatc tccagtagat
     1801 gttctttata aattagctaa tgactattca gtagttttac ttagtggaaa tggattctat
     1861 ggccctgaat ggtcaattag aatatctcta gcaaatctat atgatgaagc ttatactaag
     1921 ataggaaaag ccataagaga gatattaaat ggttatatcg ttgaatggca aaaaattaag
     1981 aaataattat attacactga aatatctaaa ttatatgaat aaaagagttt atgtagacct
     2041 taactacttt ttttgatata atcctatcgg aattataaat tttatttatg aaaggcagag
     2101 aatagtatga gtattaagaa aaaagttgcc atagttttta ctggtggaac tatatctatg
     2161 acagtagatg ataaagtcgg agcagctata ccaactttat caggtgaaca aatactatca
     2221 atggttacca acattgataa agttgcagat gttgaagttt ttaattttga tgaaattcca
     2281 ggacctcaca taacacctta tagaatgatg gaattgaaaa attatgtaaa tgatttatta
     2341 gcaagaaaag atattacagg cgttgtaata acacatggta cagatagttt agaggaaaca
     2401 gcttattttc tagaccttac aattgacaac atcaaacctg taatagtcac aggtgctatg
     2461 agaagtagtt ctgaacttgg atatgatggt tcaagtaatt tatctgcatc agtttgtact
     2521 gcagtatcca aagatgctat gggaaaagga gtccttgtag ttttaaacaa tgaagtatta
     2581 ttagcttctg aagctactaa aacaaatact ctttctctaa atacatttaa atctctaact
     2641 agtggcccat tgggaataat tgactgcaac gaacttgtcc ttacaagaga tattgtaaat
     2701 agaacaatta tagatactga taaggtagaa tctaaagttg ctttatttaa agcatatgta
     2761 ggagaaaatg ctgactttat aagatttgct gttgatagtg gttataaagg tatagttatt
     2821 gaggcaatgg gtagaggtaa tattcctcct caaatgcttt ctggagttga atatgctaga
     2881 gaaaaaggac ttcctgtagt tatagtttct agatgtcatt caggtagagt attcgatagt
     2941 tatggttact ttggttctgg tagagattta aaaaatcttg gttgtatatt tggtggggac
     3001 ttgccaggtc aaaaagctag aataaaactt atcttagcac ttggaaaaac tgataacctt
     3061 gatgaaatca aagatttctt tgaaaaagga atctattgct aattctaata acttctattt
     3121 aattatttat tgatatttca acatttttaa atcaaaatct aatacttatg tcagttaaat
     3181 gtcagcaaaa tattttatcc acaattttta cacaagtttt ccacaactta cccccaatat
     3241 tatccacaag aaaaaaggta gcacttatat tagtagctac cttttattta ttaatcttca
     3301 tctttccagc tttttatcca atttcctatt tctattattt tttcttcagt tatttcttct
     3361 ccatcatgca attttgaaat tagttctgat aatggattgt tatgtagacc tccaaaaatt
     3421 ctttttccct ctattttgag atattctttc tcttttatta atactctata gtgtacatgt
     3481 ttcccaattc tctgcgatat gaaaaaacct tttttagtta atctagctaa aagtgtaatt
     3541 gtagttgtat gcttccaagc atatgttttt tctatttcat ctgcaacatc ttttgatatt
     3601 acagttttat aaccagtatt ccatatgtat ttcataattt ttaattctgc atctggtaat
     3661 tttttattca acataatata ttccttcttt caatttatgt cacttcctca aacttatcta
     3721 gcttaaatta ataataggag ctttttatca caaaaactac aggtaaattt ttctatatat
     3781 tctacgtatt tagtctgttt tttaagtgtg aaattacgtt catacctata aatttattca
     3841 attttcaaac aatcttgttg aataataact aattctattg tattatttag ttatagaata
     3901 aaactaaatc ggcaaaacta gagaaatcta gtgacgcaaa gctataggga ctaagactta
     3961 tataaatatc ttatgagtta tgtcagccag ttgccaaaga gatattgttc tttttgtttt
     4021 tatgaaagtt ttttaggggg ataataattt atatgtttag agataaaatg gataaatgta
     4081 cacatatatt gactgcttat attagcagtt cgtatgatta ttgtaatttt ttggatacaa
     4141 tttacattcc atatagttaa tataaaacca gaagaacaac gaacaatgta tttgtcaatg
     4201 ataggattta cattccatat agttaatata aaactatcta catctttgaa ttgttctgaa
     4261 ggctctccta tatttacatt ccatatagtt aatataaaac gttacataag gttaagagac
     4321 tgcatgtaat gctactattt acattccata tagttaatat aaaactttta atgctttttc
     4381 tgcaactcct gttatagcat catttacatt ccatatagtt aatataaaac ccgcaaagtt
     4441 ggaaataaaa cttccaggct atttcaaatt tacattccat atagttaata taaaaccagc
     4501 agatttacac aaggaatatt gcaaagtagc gaacatttac attccatata gttaatataa
     4561 aaccttgaaa aaggcgaaat ggttgtgata agacctatta aaatttacat tccatatagt
     4621 taatataaaa cttttttacg tatggcatta tatgtggcgt tatttctatt tacattccat
     4681 atagttaata taaaacaccg actacttttc ccctgctgtg caaaataaag cggatttaca
     4741 ttccatatag ttaatataaa accccaaaat aaattgagta tttccaatgc ctacacatat
     4801 acaaatctct caaatttgca gtgaaccatg ggtagtgcaa ttgataacac ttatcacaag
     4861 tcctcaatgc cttatatttc aactgttaag ccttaatttc ttcaaaaaat cgaacactgc
     4921 aaaatttcta tgactttatt atatcataaa aatattattt ttgaatatct gtaccaattt
     4981 gtgatataat aaaagcaaga agaactacaa tctattttgc tgtagagtgg agttcataat
     5041 ttagaaatta cttagtttta tggaatctga tttttaaatc aaattcccaa ccactcttag
     5101 ttgccgcttt gagtggtttt ttacgctttc taaatagttt gctagctata taaactatta
     5161 agctagcaga tagacttgct agtatgcctt gtaaaaaatt atccatgtat attcacctcc
     5221 cttcttaacg tcgggaggat aattttttga tacatgaact ccactctata aattgtagat
     5281 tacatcttct tgctaaaaat attataacat ataattctta catattttac ctatttatta
     5341 ctttttacat tataataata ttcttttaat caaaaaaaca cctactatta aagtaaatgt
     5401 ttttaagtat ttttaatttt aagatccata tagttcatat gaaactaaat ataataactc
     5461 aacatatgag caatatcgag acatttacat accacatagt taatataaaa cgaaaataaa
     5521 aaaattaaac ttataaaacc cttattaatt tacataccca ctagttattt atattcaaaa
     5581 aaatcttctc catctgggtt ataaaataat attctacttg ccaatccttg ttcatattta
     5641 taattttctt tatcacctac ataagaaaat gttaatgtca tgcttcttga tggatctaat
     5701 gaaattatat ctaaataaat agtacatttt tctcctggct ttaatacacc gaaactatta
     5761 aaatccattt ttattttagc atattgcccc atatataatg ttgaattagc ttctccataa
     5821 acttttaatt ttgttacatc taaattttgt gtacttgtat tttctatatt tataggaact
     5881 gttgggtctt tatatttttc agtataatat tcaaggttat catcataaca ttcaagataa
     5941 cttcctttat cttgccaaat tatgtgcttt gaatcaaaat caatctttaa tccacatatt
     6001 atatttttat ttgaagacgg aagactaata ttattgatgg tattttcaca ctctagcata
     6061 attttatcac ttagatttcc tatcccagtc acttttgcag catttttaag tatatcttta
     6121 ttacttccaa tatcaactag tacaatagga ttatttttag ccattggtga agcaactaaa
     6181 gcataaacta aatcagtacc actagctata taaaattctt ttgcgccatt atagaactta
     6241 tttactattt ttttattagt atcatatcta tctactccac ctaatctagt tgaattagta
     6301 tcattaacta gtttgtcact cattgatgaa gtaccaccta ttacataact ttctacacca
     6361 gttgtattaa atggaacact ttttccatca gttaatacta tagctgcttt atctctaact
     6421 gctacaggtg cagcactcat tgcatcaggc tctcctttaa aagcattagt caatataact
     6481 ttatttactt tgttaattga gtttatttct tttgcaacat tatagcttgt cttaattcta
     6541 tcactacctt gaagtctttt agcctctatt cctttatctt ttagaagagt ttctgttgct
     6601 ttatcaatag aactttctcc acctattatg tatacctttt tagctttctc tactctttta
     6661 agagttgcat taggtatgtt atttttctta gttaaaaaaa ttggtgcatt tgttgctcct
     6721 gcaagtccac tcgcacttaa tccatcagcc attgtgctgt ctgcattaat taatatagct
     6781 gtagtataat tttgttcatc agctataaga gcagccgttt catatttatc ttttccttga
     6841 atagtataaa ttgtatcaag tgcattagct gatataggac cagcagcaaa cattgacacg
     6901 gctaacccta gtgataataa tttctttaat ttcacaatat ctcccccttt tatatatgaa
     6961 atactatata tcttaataat tctacattaa attttctttt cctcctttaa cgatatttat
     7021 cttcctgtta atttaagtgt atacaaatac gtgttataat gtaactgtaa agaattaaaa
     7081 agataatgac ataattagag cagtccaact gttcttttat aaaactaact tataaaggga
     7141 gcgtacatat atgaatatca aatcagcttt tataagaaaa aggatgctga aaaacattta
     7201 attgaaataa agtctactat aaataataat aagtttgttg ctccaaaagg tatgacattt
     7261 gtagaaagat gttataaata tatagacatg aataaaaata attggtctcc atatactgtt
     7321 acaaatacaa aatcttgggt taaaaattac atagaacctt ttttaagaat ctaaaactca
     7381 cagaagtaaa tcctagttca gtacaagctt ttgtaaatta taactttaat aattctacct
     7441 ttactagtgc taaagtaagg tatagctttc taagttctgt aataagggaa gcatatagat
     7501 taagagaaat acaagaaaat tcatgtgatt ttataaaact tccttctaaa gaaaaatatt
     7561 ctacaaatga aatatacaat agaaaagaag tattattgct aatagaaaag ttacttagta
     7621 ataatataga aatacctatt cttttaatgt tacttctagg tttaagaatg ggagaagcta
     7681 ctgggcttag gtggtcagat gttgacttag ataacaatct gataaatgtt aatcaaattc
     7741 ttgtctattc taatggcaaa atatctttta aagagccaaa aacaccaaaa tcaaaaagag
     7801 ctttatcagc tccaaaagaa ttaattgaaa aattgaaaat tgaaaaacta agacaaagca
     7861 aattaaaatt gcaaggtatc ctggaaaaca aaaataactt agtttgtcta aacaccaatt
     7921 taaatccgtt tctaccttct tcactaagaa aaacgtttca taattttaca aaaaaaataa
     7981 tctaaaaaaa attagaatac atgatttaag acatacaagt gctactctgc tgcttttggg
     8041 aggtactaat atgaaagttg tttctgaaag attgggtcat acagatataa aaataactat
     8101 gaatagatat tctcatgtac ttaaagaaat ggacaaagaa gcttccgaca atctaagcga
     8161 acttctattt aaatagtaaa aactgactgt cagttaaatg tcagttaaac ctaaaaaata
     8221 ggttttgtca gttgattgtc agtcaattat tttataatag tttcacttaa aaacgtctat
     8281 atctacacat tttactattt atttatgctt actaatatct atctgttatt actaattcta
     8341 atagcttcta tttaattatt tagttcagtt tacaagaaaa tacacacaaa ccataaaatg
     8401 agatgttgac aacataacag acagtatgct cctgtaaaag gtaacatact atctattata
     8461 ttgtctggat tcccaaatta gctatttgga acttaactaa aaaatcctaa tataagggca
     8521 actattataa tggcaatcgg aatacatact gtgtaatcct gttccataga gtcatcatct
     8581 gaatgtagtt ttacaattcg caatttagca atcagtttga agcagaaata gcctattatt
     8641 gttccaatta cattcgtgag taagtcgtct atatcggttg ctctgtgtaa cgtaaaaagc
     8701 tgaatagttt cgataaaaag agataatcca aaaccaatca agaatgtatt tctcaaacgt
     8761 tcaaaggttt tgcttataag cggacataaa aaacctaatg ggacaaaaag taaaatattc
     8821 aaaataaaac tcaaactaaa tccatcacta aaaggaataa gatttatgtt tagattaaag
     8881 aacgtttccc ctaactgtga cagtcttata tattcactga atgtagggat accaacaata
     8941 tgcgatagtg ttaaacataa gtagtaatac attgccagtg ataaaataga tgtttttacc
     9001 tttggaatat cactattttt cttgaatatt acaactaaga aaataccaat caagataatt
     9061 cccaacaaga aaataggatt aattaacaat aaatctttga tagcttcaaa cagactgagt
     9121 tgaatttcta cacctgattg attatttgtt acagtctcca tttgtacata cctcctcata
     9181 acatttcaat tatttctaaa aaacaaaata gaagataaat cttaaaatca tcctatcaaa
     9241 atttttaaat ttgcctttat cagtttatac caccagttaa ttcctgtctt acttctgtat
     9301 ggtattcttg ggattctttc atcaaattag acaaaaaaat ggttaccata tcaataaact
     9361 ggttacgctc catatctccc gaagcaacca tcccctgaga ataaatccgt atcaggaatc
     9421 tccacatcta ctgcacctat cacaagttat ttgataacat cctcaaacaa tctcaacttg
     9481 gatatatcag caacacccat tagaatacta ctgctgacca tccttgtttt cctggtgata
     9541 attttaatca actgggaagt tgaaacgcct atcttttttg caagttcctt tttagaaaca
     9601 tggtagctat tatatgaatc tgaatttcgt tgtctgggtg tttcatataa agcatagata
     9661 cgcacctttt ttgcctgttt tcattatata gaaaaaaatt tcaaaataca ataattatat
     9721 ttttttcgtt taagcttaga gcagttcctt gatgaacaac actttggaaa ctgaatgatt
     9781 tacataccac ttaatacatt aactcgattt aacattaatt ataataatat ttaaaacaac
     9841 aattagggta tataagaatg aactttttag ttctttaatc atttttttgt ataaaatcaa
     9901 atctattttt ataatttcaa caattttata atttcaacaa tgaaaaaagg cttatctcta
     9961 ttttagtata atccccttat agtagacatt taaataaaa
//
LOCUS       DACTZW010000119         9751 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.120, whole genome shotgun sequence.
ACCESSION   DACTZW010000119 DACTZW010000000
VERSION     DACTZW010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9751
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.120"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            235..1638
                     /locus_tag="JAM15_17295"
     CDS             235..1638
                     /locus_tag="JAM15_17295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAT6800004.1"
                     /translation="MEKKKIGLWSLVFMNVSALYGIRWIAKSTASSFGLGLGAIPMWL
                     LFSFIYFVPGALICAELASTYQKGDGGLYDWVKEAFGEKYGFLVSWLNWTAKIFWYSS
                     FLTFLAVNVSYTIGNPALADNKMFVLILSLIIFWALSLIATKGISFTKIFTNTGALGS
                     TIPSAILIIFSFVAVFVLKKHDIASTYTIASMTPKLNMDAFVAISAIMFGLAGAETAA
                     NFITEIDKPEKNFPKAILISAGIVASLYVLGSIAITMIIPPDQITASKGVLDALSAVC
                     TSLGIGSWLVQLIAFGIAFSVLGAIVLYIASPIKMLFGSVKKGIFPDSLVEVNEHKIP
                     SKAVILQAIIVTIILLVTTLMPSVDAIYNVLVTMTALTALFPYVLLYASYIKLRKERP
                     DEIRPYTMAKSTSTCLGLAKMVLVVTVVGILLSAAPVMPTFAENVIYEIEMIGGGLLV
                     ILSGLWLWNRYEKKTAK"
     misc_binding    1729..1969
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            2012..2710
                     /locus_tag="JAM15_17300"
     CDS             2012..2710
                     /locus_tag="JAM15_17300"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HAT6800005.1"
                     /translation="MNVIGIIGAMDEEVSILVDLMDIRETIKKASLEFYKGILKGKNV
                     VLVKCGIGKVNSALCAQILISEFKVDAIVNTGVAGALNEKLDVNDIVISTDAIQYDVD
                     TTAFGDPKGVIPRMKTSVFKADERLIDAAYKSSVEEVKTHKVLKGRVVTGDKFINSKE
                     LKEELVNDFGGYCGEMEGGAIAHVCYLNNTPFVIIRAMSDKADGSADVTYDVFVHDAA
                     NNSKDIVLNMLKSI"
     gene            2733..3734
                     /gene="trpS"
                     /locus_tag="JAM15_17305"
     CDS             2733..3734
                     /gene="trpS"
                     /locus_tag="JAM15_17305"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HAT6800006.1"
                     /translation="MSEKKVIFSGAQPSGKMTLGNYLGAIKNWTELQDNYDCYYSIVD
                     LHAITVPQDPKVLRANAIELLAQYIACGLDPEKNTIFIQSHVKEHVELMWVLNTMAYM
                     GELSRMTQFKDKSQKSEANLNAGLFTYPVLMAADILLYQTDLVPVGDDQKQHLELARD
                     LANRFNNRFSPTFVVPEGYYPKGGARVMSLQEPTKKMSKSDSNENAFILLADDSDSIK
                     RKIKRSVTDSLGVVKYNDEQPGIKNLIDIYSNLSKKSVEEIVNMYEGKGYGIFKEDVA
                     EVVSEALRPIREKYVDLLNNKDYLEKIYSMGAEKAEKQARKTLRKVYKKVGFIERRY"
     gene            complement(4386..7016)
                     /gene="cdtB"
                     /locus_tag="JAM15_17310"
     CDS             complement(4386..7016)
                     /gene="cdtB"
                     /locus_tag="JAM15_17310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094607992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylating binary toxin binding subunit
                     CdtB"
                     /protein_id="HAT6800007.1"
                     /translation="MKIQMRNKKVLSFLTLTAIVSQALVYPVYAQTSTSNHSNKKKEI
                     VNEDILPNNGLMGYYFTDEHFKDLKLMAPIKDGNLKFEEKKVDKLLDKDKSDVKSIRW
                     TGRIIPSKDGEYTLSTDRDDVLMQVNTESTISNTLKVNMKKGKEYKVRIELQDKNLGS
                     IDNLSSPNLYWELDGMKKIIPEENLFLRDYSNIEKDDPFIPNNNFFDPKLMSDWEDED
                     LDTDNDNIPDSYERNGYTIKDLIAVKWEDSFAEQGYKKYVSNYLESNTAGDPYTDYEK
                     ASGSFDKAIKTEARDPLVAAYPIVGVGMEKLIISTNEHASTDQGKTVSRATTNSKTES
                     NTAGVSVNVGYQNGFTANVTTNYSHTTDNSTAVQDSNGESWNTGLSINKGESAYINAN
                     VRYYNTGTAPMYKVTPTTNLVLDGDTLSTIKAQENQIGNNLSPGDTYPKKGLSPLALN
                     TMDQFSSRLIPINYDQLKKLDAGKQIKLETTQVSGNFGTKNSSGQIVTEGNSWSDYIS
                     QIDSISASIILDTENESYERRVTAKNLQDPEDKTPELTIGEAIEKAFGATKKDGLLYF
                     NDIPIDESCVELIFDDNTANKIKDSLKTLSDKKIYNVKLERGMNILIKTPTYFTNFDD
                     YNNYPSTWSNVNTTNQDGLQGSANKLNGETKIKIPMSELKPYKRYVFSGYSKDPLTSN
                     SIIVKIKAKEEKTDYLVPEQGYTKFSYEFETTEKDSSNIEITLIGSGTTYLDNLSITE
                     LNSTPEILDEPEVKIPTDQEIMDAHKIYFADLNFNPSTGNTYINGMYFAPTQTNKEAL
                     DYIQKYRVEATLQYSGFKDIGTKDKEMRNYLGDPNQPKTNYVNLRSYFTGGENIMTYK
                     KLRIYAITPDDRELLVLSVD"
     gene            complement(7069..8460)
                     /gene="cdtA"
                     /locus_tag="JAM15_17315"
     CDS             complement(7069..8460)
                     /gene="cdtA"
                     /locus_tag="JAM15_17315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylating binary toxin enzymatic subunit
                     CdtA"
                     /protein_id="HAT6800008.1"
                     /translation="MKKFRKHKRISNCISILLILYLTLGGLLPNNIYAQDLQSYSEKV
                     CNTTYKAPIERPEDFLKDKEKAKEWERKEAERIEQKLERSEKEALESYKKDSVEISKY
                     SQTRNYFYDYQIEANSREKEYKELRNAISKNKIDKPMYVYYFESPEKFAFNKVIRTEN
                     QNEISLEKFNEFKETIQNKLFKQDGFKDISLYEPGKGDEKPTPLLMHLKLPRNTGMLP
                     YTNTNNVSTLIEQGYSIKIDKIVRIVIDGKHYIKAEASVVSSLDFKDDVSKGDSWGKA
                     NYNDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPVNNPNPELDSKITNIENALKR
                     EPIPTNLTVYRRSGPQEFGLTLTSPEYDFNKLENIDAFKSKWEGQALSYPNFISTSIG
                     SVNMSAFAKRKIVLRITIPKGSPGAYLSAIPGYAGEYEVLLNHGSKFKINKIDSYKDG
                     TITKLIVDATLIP"
     gene            complement(8850..9596)
                     /gene="cdtR"
                     /locus_tag="JAM15_17320"
     CDS             complement(8850..9596)
                     /gene="cdtR"
                     /locus_tag="JAM15_17320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family response regulator CdtR"
                     /protein_id="HAT6800009.1"
                     /translation="MDILIFDNDVCFGIKLKEKINNILIKEGFDNDVIRLYYNANLLL
                     KELTEKNKVKIYFIVVDAKYKISNELCDGLWIAQKIRESDYISPIIFLTNHIEMILGI
                     FDYRLEVMDFILKHDMEIAESKIKACIKIAHKRYVKEKNYRSNFFTIYSDSSLWKISF
                     DEVIYFETSAIPHKIKLVTTSRIFEFYKSLRSLSDLDACFIRVHKSFVVNKYHIVSLD
                     LKKNNIKMSNGHICRISNTYRNILKNIIKT"
BASE COUNT         3360 a         1276 c         1406 g         3709 t
ORIGIN      
        1 aaaataatat tgaaacaatt ttaaaaattt agtatcatta gaattaaagt ggtaaaactt
       61 ttaaatttat catttttaat aagatttgat ttcaaagtat ttaaggttta ttattaaaac
      121 tgtttttgaa tatgcaaata ttttgaaaaa tatcagttta ataataatga atctatttta
      181 ttaattttga aattaaattt aaaataatta atagagaggg gaaatgaaat taggatggaa
      241 aagaaaaaaa taggcctatg gagtttggta tttatgaatg tatcagcttt atatggtata
      301 agatggatag ctaaatctac agcatcaagc tttggtttag gattaggtgc aatacctatg
      361 tggttattat tctcatttat atactttgta ccaggagctt taatttgcgc tgaattagct
      421 tctacatatc aaaaaggtga tggaggtctt tacgattggg ttaaggaagc ctttggagaa
      481 aagtatggat ttttagtttc ttggttaaac tggacagcta aaatattttg gtattcttca
      541 tttttaactt tcttagcagt aaatgtttct tatacaatag gaaatccagc tcttgctgat
      601 aataagatgt ttgtacttat attatcttta ataatattct gggcattatc tcttatagca
      661 actaaaggaa taagttttac aaaaatattt actaatacag gtgcattagg ttcaacaata
      721 ccaagtgcta tacttataat attttcattt gtagcagtat ttgtgttgaa aaaacatgat
      781 atagcttcta catatacaat agcttcaatg actccaaaac ttaatatgga tgcatttgtt
      841 gctatatcag ctataatgtt tggtttagca ggagcagaga ctgctgctaa cttcataaca
      901 gaaatagata agcctgaaaa gaacttccct aaggcaatat taatatcagc tggaatagta
      961 gcttcattat atgtattagg ttcaattgca ataacaatga taataccacc agaccaaatt
     1021 actgcttcta aaggtgtatt agatgcactt tctgctgttt gtacgtcttt aggaattggt
     1081 tcttggctgg ttcaattaat agcttttggt atagctttct cagtattagg agcaatagtt
     1141 ctttatatag catcaccaat aaaaatgtta tttggtagtg ttaaaaaagg aatatttcca
     1201 gatagtttag tagaggtaaa tgaacacaag ataccttcta aagcagttat acttcaagca
     1261 ataatagtta ctataatact attggtgact acattaatgc cttctgttga tgctatatac
     1321 aatgttcttg taactatgac agcattaact gcattattcc catatgtatt gttatatgct
     1381 tcttatatta aactaagaaa agagagacca gatgaaatta gaccttatac tatggcaaaa
     1441 tcaacaagta cttgcctagg tttagcaaaa atggttttag ttgtaactgt agtgggtata
     1501 ttattatctg cagcaccagt tatgccgaca tttgctgaaa atgttatata tgagatagag
     1561 atgattggtg gaggtcttct agttatatta tctggtctat ggttatggaa tagatatgaa
     1621 aagaaaacag ctaaataaaa tgtattttaa aaatttcttt tggatattat aatatatagt
     1681 tgacaattta tagtgtaagg aatattataa aataaagaaa ttaataaatt aaatcctgag
     1741 ataagaaata gtaaataaat atatttttgc acagagaatt aaggaggctg agaacttaat
     1801 aaaaagtatt tattgaatgg gtctttgagg agtaaaatga aatgtaattt aagattacag
     1861 agtatttgat atcgtgtatg cacgttatag catatattaa gatatatata ttcagttttg
     1921 agtgtatata aatttaggtg gtaccacgga aaatatatcc gtcctattga tttaggacgg
     1981 attttttaat atagaaaatt taggaggaaa aatgaacgta ataggaatta taggtgcaat
     2041 ggatgaagaa gttagtattt tagttgattt aatggatatt agagagacta taaaaaaagc
     2101 tagcttagaa ttttataagg gaattttgaa aggtaagaat gtagtgttag taaagtgtgg
     2161 tataggtaag gttaactctg ctctttgtgc ccagatacta ataagcgaat ttaaggttga
     2221 tgctattgtt aatacaggtg ttgcaggagc tttaaatgaa aaacttgatg ttaatgatat
     2281 agtaatatca actgatgcta tacagtatga tgtagatact acagcatttg gagaccctaa
     2341 gggagttata ccaagaatga agacttctgt atttaaagca gatgaaagac ttatagatgc
     2401 tgcttacaaa tcttctgtgg aagaagtaaa gactcataaa gtattaaaag gaagagtagt
     2461 tacaggagat aaatttataa attctaaaga attaaaagaa gaattagtaa atgattttgg
     2521 tggatattgt ggagaaatgg aaggtggagc tatagctcat gtatgctatt taaataatac
     2581 tccattcgta ataataagag caatgtctga taaggcagat ggaagtgctg atgttactta
     2641 tgatgtattt gtacatgatg ctgccaataa ctctaaagac atagttttaa atatgttaaa
     2701 atcaatataa atatataagg aggtacaaaa aaatgagtga aaaaaaagtt atatttagtg
     2761 gagcacagcc atcaggcaaa atgactttag gaaattattt aggagctata aaaaactgga
     2821 ctgaacttca agataattat gattgctatt atagtatagt tgatttacat gcaataacag
     2881 tacctcagga ccctaaagtt ttaagagcga atgctataga attacttgct caatatatag
     2941 cttgtggatt agacccagaa aaaaatacta tatttataca atcacatgtc aaagagcatg
     3001 ttgaacttat gtgggtattg aatactatgg cttatatggg tgaattaagt agaatgactc
     3061 aattcaaaga taaatcacaa aagagtgaag caaatctaaa tgcaggttta ttcacatatc
     3121 cagttcttat ggccgctgac atattgttgt atcaaactga cctagttcca gttggagatg
     3181 accaaaaaca acatttagaa ttagctcgtg atttagcaaa taggtttaat aatagatttt
     3241 cacctacttt tgtagttcca gaaggatact acccaaaagg tggagcaaga gtgatgagtt
     3301 tgcaagagcc aactaaaaaa atgagtaaat ccgattcaaa tgaaaatgca tttatactat
     3361 tagcagatga ttcagattct ataaagagaa agataaaaag aagtgttact gattctttag
     3421 gtgttgtaaa atacaatgat gaacaaccag gtattaaaaa tctaattgat atatattcta
     3481 atttaagtaa aaagagtgta gaagagattg taaacatgta tgaaggaaag ggttatggca
     3541 tatttaaaga agatgtggct gaagtagtat cagaagcttt aagacctata agagaaaaat
     3601 atgttgacct tcttaataat aaagattatt tagaaaaaat atatagtatg ggagcagaaa
     3661 aagccgaaaa acaagctaga aaaactctta gaaaagttta taaaaaagtt ggatttatag
     3721 agagaagata ctaattatta gctatcttta cttgataaat aaattttaaa gttattaaaa
     3781 aggtatatga tatgaaagag agagtctcaa agtgaacttt tgttcatgag acactctttt
     3841 ttgtatgaaa taaaatatat tttaatcatt tcaacaatga aaaagaggat tatctctatt
     3901 ttgagacagc atcttttgat aataaaaaaa gatgagcttt tgctcatctc aaaggggtta
     3961 gattattctt actttgggga aagtagaata aaggtaaaag ttaactgatg tcaactttgt
     4021 cttttttgca tatcactact gagcataaaa aaatcagaaa accatagcct tctgaaacaa
     4081 cttctaacat acattgtatt ttatacccaa tatgtaattt atgagttaat tttaactctt
     4141 ataatggaaa ttgtcaataa tatatcaaaa aaatattttt taaatttata taattaaatg
     4201 aatttatgtt tatatatagg tgatatgata cagataatta tctttataat acaatatagt
     4261 tctaaaaaag aatatgttag aagaagagaa tatttaaata aaaaatacct tataaagtta
     4321 attttttagt actttataag gtaaatatat attgtattgt ggggacaaat ttaaatcatt
     4381 tgatactaat caacactaag aactaataac tctctatcgt ctggagtaat tgcatatatt
     4441 cttaatttct tgtatgtcat aatattttct ccacctgtaa aataactcct aagattaaca
     4501 taattagttt taggctgatt tggatctcct aaataattac gcatttcttt atctttagtt
     4561 ccaatatctt taaatccaga atattgtaaa gtagcttcaa ctctatattt ttggatataa
     4621 tcgagagctt ctttattagt ttgtgttggt gcaaaataca taccatttat ataagtattt
     4681 cctgtacttg gattaaaatt taaatctgca aaatatattt tatgtgcatc cattatttct
     4741 tggtcagttg gaattttaac ttctggttca tcaagtattt caggagtact atttagctct
     4801 gtaatagata agttatctaa gtatgttgta ccactaccaa ttaatgttat ctctatatta
     4861 gaagaatctt tttcagtagt ttcaaattca taactaaatt ttgtatatcc ttgttctggt
     4921 accaaataat ccgttttctc ttcttttgct tttatcttta caattattga attagatgtt
     4981 aaaggatcct ttgaatatcc actaaaaaca taacgtttat aaggttttag ctcagacata
     5041 gggattttaa tcttcgtctc accatttaat ttatttgctg agccttgtaa accatcttga
     5101 ttcgtagtat tgacattact ccatgtacta gggtaattat tataatcatc aaaattagta
     5161 aagtaagttg gtgtttttat aagtatattc attcctcttt caagtttaac attatatatc
     5221 tttttatcag acaaagtttt taaactatct ttaatcttgt tggctgtatt atcatcaaat
     5281 atgagttcaa cacaactttc atctattggt atatcattaa aatataacaa accatctttt
     5341 ttagtagcgc caaaagcttt ttcaattgct tctccaattg taagttcagg tgttttatct
     5401 tctggatcct gtaaattttt agcagtaact cttctttcgt aagattcatt ctctgtatct
     5461 aatataatag atgcagaaat actgtcaatt tgacttatat agtctgacca actatttcct
     5521 tctgttacta tttgtccaga actatttttt gtaccaaaat ttccacttac ttgtgttgtt
     5581 tctaatttaa tttgctttcc agcatctaat ttttttaatt gatcataatt tataggaatc
     5641 agtctagagc taaattgatc cattgtgtta agagctagag gtgaaagccc ttttttggga
     5701 taagtatctc caggagatag attattgcca atttgatttt cttgtgcttt gatagttgat
     5761 aatgtatctc catctaacac taaatttgtt gttggtgtca ctttgtacat aggtgcagta
     5821 cctgtgttgt aatatctaac atttgcattt atatatgcag attctccttt gtttatactt
     5881 aatccagtat tccatgattc tccattacta tcttgaacag cagttgaatt atctgttgta
     5941 tgggaataat ttgtagttac attagctgtg aatccatttt gatatcctac attaacagac
     6001 acaccagctg tattagattc agttttactg ttagtagtag ctctggaaac agttttacct
     6061 tgatcagtag aggcatgttc atttgtagat ataattaatt tttccatacc tactccaaca
     6121 attggatatg ctgcaactaa cggatctctt gcttcagtct ttatagcctt gtcaaaagaa
     6181 cctgaagctt tttcataatc tgtatatgga tctccagcag tatttgactc taaataattt
     6241 gatacatatt tcttatagcc ttgttctgca aaactatctt cccacttaac tgcaattaag
     6301 tccttaatag tatatccatt tcgttcatat gaatctggta tattatcatt atctgtatcc
     6361 aaatcttcgt cttcccaatc agacatcaac tttgggtcaa agaaattgtt atttgggata
     6421 aatggatcat ctttttctat attagaataa tctcttaaga ataaattttc ttctggtata
     6481 attttcttca taccatctaa ttcccaataa agattaggtg atgataaatt atctattgaa
     6541 cctaaatttt tatcttgtag ctctattcta actttatatt ctttaccctt tttcatatta
     6601 actttaagtg tatttgatat agtactctca gtatttactt gcattaagac atcatctcta
     6661 tcagttgata atgtatattc accatcctta gaaggaatta ttcttcctgt ccatcgtata
     6721 gattttacat ctgatttgtc tttatccaga agtttatcta ctttcttttc ttcaaatttt
     6781 aaattaccat cttttatggg tgccattaat tttaaatctt taaagtgctc atctgtgaaa
     6841 taatatccca ttaatccatt gtttgggagt atatcttcat ttacaatttc ttttttctta
     6901 ttagaatgat tacttgtact agtttgagca tatacaggat atactagtgc ttgactaact
     6961 atagctgtaa gtgttaaaaa acttaatacc tttttattcc tcatttgtat tttcattgtt
     7021 tctcctcctt aaatttgaaa aatattaaat tatttatgtg aaaaaatatt aaggtatcaa
     7081 tgttgcatca acaattaatt ttgttatagt accatctttg taagaatcaa ttttattgat
     7141 tttaaatttg cttccatgat ttaaaagcac ttcatattca cctgcataac ctggaatagc
     7201 tgatagataa gctccaggag aacctttagg tatagttata cgtagtacta tttttctttt
     7261 agcaaatgca ctcatattca cactaccaat actagtacta ataaagtttg gataagacag
     7321 tgcttgtcct tcccattttg atttaaaagc atctatattt tctagtttgt taaaatcata
     7381 ttcaggggaa gtaagagtta aaccaaattc ttgaggacca gatcttctat atacagttaa
     7441 attagttgga ataggttcac gttttaatgc attttcaatg tttgtgattt tagaatctaa
     7501 ttctgggtta ggattattta ctggaccatt tgatattaaa taattattaa ttgcagtata
     7561 tcctccacgc atataatcat ttacatcagc aagttcatta ggtgttaatt tattactcca
     7621 atcattataa tttgctttac cccaagagtc ccccttactt acatcatctt taaaatcaag
     7681 actacttaca acagatgctt ctgctttaat atagtgcttc ccatctataa ctatacgaac
     7741 aattttatct atttttatac tatatccttg ctctattaat gtacttacat tgttagtatt
     7801 tgtatatggt aacataccag tatttctagg taattttaag tgcataagta atggtgtagg
     7861 tttttcatca ccttttccag gttcatataa agaaatatct ttaaatccat cttgcttaaa
     7921 taatttgttt tgtatagttt ctttaaactc attaaatttt tctaatgaaa tttcgttttg
     7981 attttctgtt cttattactt tattaaatgc aaatttttct ggagattcaa aataatagac
     8041 atacataggt ttatctattt tattttttga tatagcattt cgaagttctt tatattcttt
     8101 ttctcgagaa tttgcttcta tttgataatc ataaaaataa tttcttgtct gagaatattt
     8161 acttatttct acagaatctt ttttatatga ttctaatgct tctttttcag atctttcaag
     8221 tttttgctct attctttctg cttcttttct ttcccattct ttagcctttt ctttatcttt
     8281 aagaaaatct tctggtcttt ctataggagc cttgtaagta gtattgcaaa ctttttcact
     8341 atagctttgt aagtcttgtg cataaatgtt attaggtaac aaaccaccta aagttagata
     8401 taatatcaac aatatagata tacaattact aatcctttta tgtttcctaa attttttcat
     8461 ttattctccc tcccaatatt agtttaatta actcttgaac tttaatttat ttagattata
     8521 taatctaaat aagaattttt tatataaatt tcataaaata tgtaactata tatcataaaa
     8581 atatgtattt atatgatatg tcagtacaaa ataacaactg aatattttaa agagactatt
     8641 tcatactttt atgatttaat gagctatctt gttgaatcat aatctaggaa caatggttgc
     8701 aatgtctaat agaaattgta tatgatatag tcattatgtg ttttttcaca aaacgattat
     8761 tatatagagg attcttagga actacttttt ttgtataaaa aaagagatgg ttcaaattct
     8821 tatcttgaga catctctttt ttctatttat tatgttttaa taatgttctt taaaatattt
     8881 ctatatgtat tagatatacg acatatatgg ccattactca ttttaatatt atttttcttt
     8941 aggtcgagag aaacaatatg atatttatta actacaaaag atttatgtac acgaataaag
     9001 catgcatcta aatctgataa agaccttaaa cttttataga attcaaatat tcttgaagta
     9061 gtcactaatt ttattttatg tggaatagcg cttgtttcaa aatatataac ttcatcaaat
     9121 gaaattttcc atagtgagga atctgagtag atagtaaaaa aattagagcg ataatttttt
     9181 tctttaacgt atcttttatg agcaatttta atacaagctt ttattttact ttcagcaatt
     9241 tccatatcat gttttaatat aaagtccata acttctaacc tataatcgaa gatccctaaa
     9301 atcatttcta tatgatttgt aagaaatatg attggactaa tataatctga ttctctaatt
     9361 ttttgtgcta tccataatcc atcacataat tcattactta tcttgtattt tgcatctaca
     9421 actataaaat atatttttac tttatttttt tcagtaagtt cttttaataa caaatttgca
     9481 ttataatata atcttataac atcgttatca aaaccttctt ttattaaaat attatttatt
     9541 ttttctttta gttttattcc aaaacaaaca tcattatcaa aaattaatat atccactaaa
     9601 taccctccta taaaaaattc aaaagtaaaa aaactaaaag tattttataa aaaatacgta
     9661 aaataacact aggagataaa taaaattaag gatagttaga attaaggtat atttatgctt
     9721 gtttatatag tatatcttat acttatagtt t
//
LOCUS       DACTZW010000120         9683 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.121, whole genome shotgun sequence.
ACCESSION   DACTZW010000120 DACTZW010000000
VERSION     DACTZW010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9683
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.121"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            442..1647
                     /locus_tag="JAM15_17325"
     CDS             442..1647
                     /locus_tag="JAM15_17325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HAT6800010.1"
                     /translation="MSKKVLIMSASTGGGHNRAALAIKEELTSKTLDGEPIECEIIDS
                     LKLVNNTMDKIISRGYEKSAIYTPKAYGSVYRLSETNLLSKNEFKDNLLITFMAKKFK
                     KLIRSEKPDLIIGTHPFPMIALSTLKKNFNLHNNESNAYTEHFYKHYTNTINVPPLIS
                     VLTDYTTHSTWIQNEIDYYIVGHEYVKELLVFDGVEPSKIRTFGIPVEKSFLSHRDKD
                     IVLSELNLSPDKLTVLLMGGSFGAGNIKETLDELLDTDRDFQILVITGKNESLKEKIE
                     KKLMSRYHDKNVCVLGYTDKMNDILASIDVLVSKPGGLTTTEALLKDVPMIVPYYIPG
                     QEEENLDFLSNCGAALRTTKKYNLSILLKVLIDDPSRLEMLKRNIKSIRKSNSAQNIA
                     NLILNIISG"
     gene            complement(1718..1939)
                     /locus_tag="JAM15_17330"
     CDS             complement(1718..1939)
                     /locus_tag="JAM15_17330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800011.1"
                     /translation="MKPIMNLEEHNAMKEKRVKKMKSKDKPKYDDFEDISFSNKKKTK
                     KNVRNKNAEFRNNYKNYQYDYEEDFYEPI"
     gene            complement(2080..2679)
                     /gene="recR"
                     /locus_tag="JAM15_17335"
     CDS             complement(2080..2679)
                     /gene="recR"
                     /locus_tag="JAM15_17335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007789149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HAT6800012.1"
                     /translation="MQVYTGPITRLIEEFSKLPGVGRKTAQRLAFHIINMNTNDVEAL
                     SKAIIDAKREIRYCSICCNITDTDPCSMCSNKSRDSSVICVVEDPRDVAAMERTREFK
                     GQYHVLNGVISPMDGIGPDMLKIKELIQRLGNQEVKEIIMATNPTIEGEATAMYIARL
                     VKPMGIKVTRIAHGLPVGGDLEYADEVTISKALEGRREI"
     gene            complement(2692..3042)
                     /locus_tag="JAM15_17340"
     CDS             complement(2692..3042)
                     /locus_tag="JAM15_17340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HAT6800013.1"
                     /translation="MAKKGFGGGMMPGGGNMNNLLKQAQKMQENMQKAQQELESKEVE
                     ASVGGGAVTVKVNGKKEVIDITIKPEVVDPDDIEMLQDLVLSAVNQALRNIDDIQASQ
                     MSKVTGGMNIPGLF"
     gene            complement(3101..4738)
                     /gene="dnaX"
                     /locus_tag="JAM15_17345"
     CDS             complement(3101..4738)
                     /gene="dnaX"
                     /locus_tag="JAM15_17345"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HAT6800014.1"
                     /translation="MHKALYRAYRPQKFEDVIGQDHIIKTLKNQIYSDNIGHAYLFCG
                     TRGTGKTSTAKIFSRAVNCLNKINEEPCNECEICESVLKDNTMDVVEIDAASNNSVDD
                     IRELRESVKYSPANAKYKVYIIDEVHMLSQGAFNALLKTLEEPPSYVIFILATTEPHK
                     IPATILSRCQRYDFKRVTVKDMTLRMKKICEDEGIDIDDKALNLIARNSQGALRDALS
                     ILDQCMSFGESKIDYKDVVELMGSVNIEQLFELSQCIVEQDTKKSLEILNEFVLWGKD
                     IRNLINDLIDHFRNLMVCKVSSELDEIISLPEETIEQLKIQSKNIDINDLIRILNILS
                     ITQDDIKSSSNPRVLVEITIMKIAQPMFDESKEALIKRVENLEKMIELGNFKSEKIGN
                     NKEKEYEVDREIDVKQENVVYEDVKNEDVILIESSWKNILKQIKKDKKMPIYALLSEV
                     KSFNVYSNMLYVIFDDKFDFAKTRLSSQDTINYLEKTIRDVLNRSFNVKIVLTSEVKD
                     INLEVKEKKDIGEEILKNIVSEEILEIKDSIDENESK"
     gene            complement(4815..5079)
                     /gene="ffs"
                     /locus_tag="JAM15_17350"
     ncRNA           complement(4815..5079)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="JAM15_17350"
                     /product="signal recognition particle sRNA large type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01854"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF01854"
     gene            complement(5117..5208)
                     /locus_tag="JAM15_17355"
     tRNA            complement(5117..5208)
                     /locus_tag="JAM15_17355"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5172..5174),aa:Ser,seq:gga)
     gene            complement(5209..5664)
                     /locus_tag="JAM15_17360"
     CDS             complement(5209..5664)
                     /locus_tag="JAM15_17360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HAT6800015.1"
                     /translation="MESSFYMKEALKEAYKAYNKKETPIGAIIVKDNQIIARAHNLTE
                     TLKDSTAHAEILVIKQASEKLGGWRLTDCDLYVTMEPCIMCSGAIVNSRIKKLIIGTR
                     HVKNSYIEKQHEFKLDYFNNNNVKVAFDVLQEECSIILQEFFKALRKRD"
     gene            complement(5985..7256)
                     /gene="serS"
                     /locus_tag="JAM15_17365"
     CDS             complement(5985..7256)
                     /gene="serS"
                     /locus_tag="JAM15_17365"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006441208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HAT6800016.1"
                     /translation="MLDIKRIRENLDDIKKAMERRGEREFDLDAVVELDNKRREILQE
                     VEVMKNELNVNSKKIPQLIKEGKDVTEEKARLKELSDKIKGIDEKVKEVEAKMEYTLM
                     RIPNVPHPEVPQGETDEDNVQIRTWGEPTKFDFEHKAHWDIGTGLGILDFERAGKITG
                     SRFTLYRGLGARLERSLMNFFLNTHTAKHGYTEVLPPFMANRNSFIGTGQLPKFEEDM
                     FKIEGLEYFLIPTAEVPVTNIHANEILDVAELPIKYCAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVELVKFVKPEDSYNELESLTHDAETMLQMLGLPYRVVKICTGDLGFTAAFK
                     YDLEVWMPSYNRYVEISSCSNFEDFQARRAGIRFKRDKKSKAEYVHTLNGSGLAIGRC
                     LAAILENYQQADGSVVVPEELRPYMGVDVIK"
     misc_binding    complement(7382..7587)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(7715..8596)
                     /locus_tag="JAM15_17370"
     CDS             complement(7715..8596)
                     /locus_tag="JAM15_17370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HAT6800017.1"
                     /translation="MNFLSLAKTASTNSNITKRTLENMLDNFSDNIPNIIYAIIVFVI
                     GIYISKIVRRMVSKFLIKYGMSKGVNNFIVYGIYISMLSIISLISLGIIGIQTTSVVA
                     VLGAAGFSIGLAFKEILSNLGSGMIILFFKPFNIGDYIQGSGVEGTVSDIQIFSTVLK
                     TPDNKTIIIPNFQLTSNNIINYTHQNKRRIDFSYNISYDSDIDVVKSILNEIFTNEKR
                     ILNDPKPIIGLNSIGNNTMQIVARPWVKTDDYWDVYFDVMEKVKNKFDENDIKVPFVP
                     SSLLFNNTGNLNTMDKR"
     gene            complement(8608..9117)
                     /locus_tag="JAM15_17375"
     CDS             complement(8608..9117)
                     /locus_tag="JAM15_17375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HAT6800018.1"
                     /translation="MNSNERRSKLIDILKESKHPVKGGTLAELLNVSRQVIVQDIALI
                     RARGFEIIATPQGYIIYNQPYFTKQIKCKNHKDSKEIYDELKIIVDLGGIIKDVIVNH
                     PTYGQITAELNIYSKMDIDNFMKKVETNEFKQLSVLTECSHIHTIEAIKEETIEAIVK
                     ELKDNGILS"
     gene            complement(9244..9360)
                     /gene="rrf"
                     /locus_tag="JAM15_17380"
     rRNA            complement(9244..9360)
                     /gene="rrf"
                     /locus_tag="JAM15_17380"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(9487..>9683)
                     /locus_tag="JAM15_17385"
     rRNA            complement(9487..>9683)
                     /locus_tag="JAM15_17385"
                     /product="23S ribosomal RNA"
BASE COUNT         3078 a         1710 c         1052 g         3843 t
ORIGIN      
        1 atataaatta acctactgtt taattttcaa tgttcgtgtt tatttctttt tccttttttc
       61 aaggacaagt aatactatat catctttatc tattctagtc aatataattt tttacttttt
      121 ttaatttttt tatttatcat gtattcttta tctttaattt ttaaaactta atgctaagta
      181 aacctgttta tttcataaaa ctaatatata ttctatgctc tattttcctt tttattctat
      241 atttaaattt tttatttaca agaatatttt taatataaca tatttgataa aattaattta
      301 catttctttc acttgtaatt tttgcaatct tgtattagat taatattaaa aataatttat
      361 caataacctt attcacaaag acagttttta tatatcaaaa tataatataa atactatgct
      421 acattttagg aggattttat tatgagcaaa aaagtattaa taatgtctgc ttccactggt
      481 ggtgggcata atagggctgc tctagctatt aaagaagaac ttacttccaa aacacttgat
      541 ggagagccaa ttgaatgtga aataatagat agtttgaaat tagttaataa tacaatggat
      601 aaaataattt caagaggata cgaaaaatct gctatatata ctcccaaagc ctatggaagt
      661 gtatatagat tatctgaaac aaatcttttg tcaaaaaatg aatttaaaga taatctacta
      721 ataacattca tggctaaaaa atttaaaaag cttattagaa gcgaaaaacc agacttgatt
      781 ataggaacgc atccttttcc aatgattgct ctaagtacat tgaaaaaaaa ctttaattta
      841 cataataatg aatcaaatgc ttacacagag catttttata aacattatac aaataccatt
      901 aatgttcctc cgcttatttc tgtattaacc gattatacta ctcattctac atggatacaa
      961 aatgaaattg attactatat tgttggtcat gaatatgtaa aagaattatt ggtgtttgat
     1021 ggagttgaac cgagtaaaat tagaacattt ggaatccctg ttgaaaaatc ttttctctct
     1081 cacagagata aagatattgt tctttctgag ttgaatttat ctcctgataa attaactgtt
     1141 ttacttatgg ggggtagctt tggggctgga aatataaaag agacacttga tgaattactg
     1201 gatactgata gagactttca aatacttgta attactggta agaatgaaag cctaaaagaa
     1261 aaaatcgaaa aaaaacttat gtctcgttat catgataaaa atgtatgtgt tcttggatac
     1321 actgataaga tgaatgatat tttagcttcc atagatgtat tagtaagcaa acctggtgga
     1381 cttactacaa ctgaggctct tttaaaagat gtacctatga tagttcctta ttatatacca
     1441 ggtcaggaag aagagaatct tgatttctta tctaattgtg gtgcagcact tagaactaca
     1501 aaaaaatata acttgtcaat attactaaaa gttttaatag atgaccctag cagattagaa
     1561 atgctaaaaa gaaatattaa atcaataaga aagtcaaatt cagcccaaaa tatagctaat
     1621 ttaattttaa atataatttc tggttgataa aataaataaa atccctatag tatatatatt
     1681 atctattagg gattttttat tttctaatta tttaatatta aattggttca taaaagtctt
     1741 cttcataatc atactgataa tttttataat tatttctaaa ttcagcattt ttatttcgta
     1801 catttttttt agtttttttc ttattagaaa aacttatatc ctcaaaatca tcatatttag
     1861 gtttatcttt tgatttcatt tttttaactc ttttttcttt cattgcatta tgttcttcta
     1921 agttcataat tggtttcatg ttgcacccct atcaaaattt ttaaatgatt tatacaacaa
     1981 attatacaat acagaagaaa tttattcaat aaatctaaat caaaattaat ttgaatttaa
     2041 ctcaaaaaac tacaaaaatc gaggtattaa cctcgatttt tatatttctc ttctgccttc
     2101 tagtgctttt gatattgtga cctcatctgc atactctaaa tcgcctccaa caggaagacc
     2161 atgagctatc cgagtgactt tgattcccat tggttttact aacctagcaa tatacatggc
     2221 tgtagcttca ccttcaatag taggatttgt tgccattatt atttctttga cttcctgatt
     2281 gccaagtctt tggataagtt cctttatttt taacatatct ggtccaattc catccattgg
     2341 agaaattact ccatttaata catgatactg tcctttaaac tctctcgttc tctccatagc
     2401 tgctacatct cttggatctt ccacaacaca tataacactt gaatctctac ttttatttga
     2461 acacatgcta catgggtctg tatctgttat attacaacaa attgagcaat atcttatttc
     2521 tctttttgca tctataatcg ctttagataa agcttccaca tcattagtat tcatattaat
     2581 aatatgaaaa gccaatcttt gagcagtctt tcttcctact ccaggaagct ttgaaaattc
     2641 ctctataagt ctcgttatgg gacctgtata aacttgcata aataccacct actagaataa
     2701 cccaggtata ttcatacctc cagttacctt actcatttga cttgcttgta tatcatcaat
     2761 atttctcaat gcttgattta ctgcacttaa aactaaatct tgtagcattt ctatatcatc
     2821 tggatcaact acttctggct tgatagttat atctataact tcttttttac cattaacttt
     2881 tacagtaact gctcctccac caactgaggc ttctacttct ttactttcta actcttgttg
     2941 agctttttgc atattttctt gcattttttg agcctgcttt aacaagttgt tcatatttcc
     3001 accaccaggc atcattccgc ctccaaaacc ttttttagcc ataaacacta ttcctcctaa
     3061 acttattttc attttattat tatatcataa tagtatttta ttatttactc tcattttcat
     3121 caatactatc ttttatttct aatatctctt cactcactat gttctttaat atttcctcac
     3181 caatgtcctt tttctcttta acttcaagat ttatatcttt aacttctgat gtcagtacta
     3241 tttttacatt aaaacttcta tttaaaacat ctcttattgt tttttctaaa taatttattg
     3301 tatcttgaga gctcagtcta gtttttgcaa aatcaaattt atcatcaaat ataacataca
     3361 acatattaga atatacatta aaacttttta cttcacttaa gagtgcgtat attggcattt
     3421 ttttatcttt tttaatttgt ttaagtatat tcttccaaga tgactctata agtataacgt
     3481 cctcattttt tacatcttca taaactacat tttcttgttt tacatctatt tctctatcga
     3541 cctcatactc tttttcttta ttattcccaa ttttttcaga cttaaagttc cccagttcaa
     3601 tcattttttc taagttctca actcttttta taagagcttc tttactttca tcaaacattg
     3661 gttgagcaat tttcattatg gttatttcca ctaaaaccct tggatttgaa gatgacttta
     3721 tatcatcctg agttattgat aatatattta aaatccttat taaatcattt atatctatat
     3781 ttttagactg aattttaagt tgttctatag tttcttctgg taatgaaatt atttcatcca
     3841 attctgatga aaccttacat accattaaat ttctaaaatg atcaattaag tcatttataa
     3901 gatttcttat atctttgccc cataagacaa attcatttaa tatctcaaga gactttttag
     3961 tgtcctgctc tacaatacat tgagacaatt caaataattg ttctatattt acgcttccca
     4021 ttaattcaac aacatcttta taatctatct tactttctcc aaaagacata cattggtcta
     4081 atatactaag tgcatctcta agagctcctt gagaatttct agctattaaa ttaagagctt
     4141 tatcatctat atcaattcct tcatcttcac aaatcttttt cattctaagg gtcatatctt
     4201 taactgtaac tcttttaaaa tcgtatcttt ggcatcttga taaaatggtt gcaggtattt
     4261 tgtgaggctc tgtagttgct aatataaaaa ttacatatga tggaggttcc tctaaggtct
     4321 ttaataatgc attaaaagct ccttgagaca acatatgaac ttcatctatt atatatactt
     4381 tatatttagc attggctgga gaatatttca cactttctct aagctctctt atatcatcta
     4441 cactattatt tgaagctgca tctatttcta caacatccat tgtattatct tttaatacag
     4501 attcgcatat ctcacactca ttacacggtt cttcatttat tttattcaaa cagtttactg
     4561 ctcttgaaaa aatctttgca gtagatgttt taccagtacc tcttgttcca caaaacaaat
     4621 aagcatgtcc tatattatca ctatatattt gattctttaa agtcttaata atatgatctt
     4681 gaccaataac atcttcaaat ttttgtggtc tatatgctct atataatgct ttatgcatct
     4741 ttttacctct ctttagcaaa attaataaaa aaatccctca ttatctaagg gattagtctt
     4801 ttatatatta aatgctgtac accatctatc gacttaattc cataggcgtt accaaaacag
     4861 ttagctcaac ttaggcaccc ccacggcaca caaaagtgat cacttaccgc tgcttccttc
     4921 cggatctgac ggggttcatg agctttcatt gcgcaggacc taagcatcaa caccacttat
     4981 ttagggcggc cctacagaaa ataagccttt agatggaatt caatcctgct atagcggatt
     5041 gcaggttaca gggcaccgct acctccccat ctagtacagc aaaattacaa ccatatttaa
     5101 ttactttcat tgtttctggc ggagagagtg ggatttgaac ccacgataca gttttaccca
     5161 tatactcgct ttccaggcga gcgccttcga ccactcgacc atctctcctt aatctctttt
     5221 tctcaatgcc ttaaaaaatt cttgcaatat gatcgagcat tcttcttgca aaacatcaaa
     5281 agctactttt acattattat tattaaaata atctaattta aactcatgct gtttttctat
     5341 atatgaattt tttacatgtc ttgtccctat tataagcttt tttattctag aattaactat
     5401 tgcgccacta cacattatgc aaggttccat tgtaacatat aaatcacaat cagtcaacct
     5461 ccaaccacct aatttttctg atgcttgttt tatcactaaa atttctgcat gtgctgtaga
     5521 gtcttttaac gtttctgtaa ggttatgagc tctagctatt atttgattat ctttaactat
     5581 aatagcacct attggtgttt cttttttatt atatgcttta tatgcttctt ttaatgcttc
     5641 tttcatataa aatgaacttt ccataattcc tcccaaaact tataacaaac ttatcttatc
     5701 ataattcatt ttataattca acttaatttt attttgttta tttaattatt actatatata
     5761 gctatatttt ttttaaatta gttctaaaat aatttttaga tattcataca agagtgtttt
     5821 ataaaaatat ttagtgtttt atgatgaaaa ttctgctgtg taaattaaaa taaaaaaact
     5881 atgaaattaa tatttataat aatttcatag tttttttatt tattatttac tcataatata
     5941 ttctcttcat caaagcatac tctacatata caattaatat aaatttattt tataacatca
     6001 acacccatat aaggtcttaa ttcttctgga actactacag aaccatctgc ctgctgataa
     6061 ttttctaata tagcagccaa acatcttcct atcgctaatc cagaaccatt taatgtatga
     6121 acatattctg cttttgattt tttatctctt ttaaatctta ttcctgctct tcttgcttgg
     6181 aaatcttcaa aatttgaaca agaagatatt tctacatatc tattgtaact tggcatccaa
     6241 acttctaaat catatttaaa tgcagctgta aatcccaaat ctcctgtaca tatttttaca
     6301 actctatatg gaagacctaa catttgtaac atagtttcag catcatgagt taatgattct
     6361 aattcattat aagaatcttc tggtttaaca aatttaacta attcaacttt attaaattga
     6421 tgttgtctaa ctaaacctct tgtatctctt cctgctgaac ctgcttcaga tctaaaacaa
     6481 ggagtatatg cacagtattt aattggaagc tctgcaacat ctaatatttc attagcatgt
     6541 atattagtaa caggaacttc agctgttggt attaagaaat actctaatcc ttctatttta
     6601 aacatatctt cttcaaattt aggaagttga ccagtcccta taaaactatt tctattggcc
     6661 ataaatggag gtaagacttc cgtatagcca tgcttagctg tatgagtatt taaaaagaaa
     6721 ttcattaaag atctttctaa tctagctcct aatcccctat ataaagtaaa ccttgaccca
     6781 gttattttcc ctgctctttc aaaatctaaa atacctagac ctgtacctat atcccaatgc
     6841 gctttatgct caaaatcaaa tttagtaggt tctccccaag ttcttatttg aacattgtct
     6901 tcatctgttt caccttgtgg tacctctgga tgaggaacat ttggtattct cattaatgta
     6961 tattccattt ttgcttctac ttcttttact ttctcatcaa taccttttat cttatctgat
     7021 aactctttca atcttgcctt ttcttctgtt acatcttttc cttcttttat taattgaggt
     7081 atttttttag aatttacatt taactcattt ttcataactt caacttcttg aagtatttct
     7141 cttcttttat tatctaattc cactacagca tcaaggtcaa attctctttc acctcttctt
     7201 tccatagctt ttttgatatc atctagattt tctcttattc ttttaatatc taacatatta
     7261 attcctccta ataattttga taatataagt tataattcca acttaattta caaacattat
     7321 acttgtaaac tcttagttta aacaaatttt aaaaataaaa aaagacctcc gtttacccta
     7381 taaaagggac gaaaatcttt tatccgcgtt gccaccctaa ttgactatac taaaatgtat
     7441 aatcctctca gacctataac gtaggtaaac gtctagcttt aactagaagc tctagagtag
     7501 attcaaaaac cattgtaatg agttttcacc atccactcat tctctgaata caatctgttt
     7561 tttactattt tccttcacag ctttttaact aattgtttta tttgataatc attatattat
     7621 atatattaac atctttcaat actattattc aaattttttt agaattttct ttaatttttt
     7681 atattaaatt cattttttct atttaattaa gaccttatct tttatccatt gtatttagat
     7741 tacctgtatt attaaataat aatgaagaag gaacaaatgg aacttttata tcattctcat
     7801 caaatttatt ttttaccttt tccattacat caaagtatac atcccagtaa tcatcagttt
     7861 ttacccaagg tctagcaact atttgcatgg tgttatttcc tatagagttt agacctatta
     7921 taggctttgg atcatttaat attctttttt cgtttgtaaa aatttcattt aatatagact
     7981 taactacatc tatatcacta tcatatgaaa tattatatga aaaatctatt cttcttttgt
     8041 tttgatgtgt gtaattaatt atattattac ttgtcagttg aaaattaggt ataattatag
     8101 ttttattatc tggcgtctta agaacagtgc taaatatttg tatgtcagaa actgtacctt
     8161 ctacacctga accttgaata taatcaccta tattaaatgg cttaaaaaat aaaataatca
     8221 taccagagcc taaatttgat aatatttctt taaaagctaa acctatacta aatccagcag
     8281 ctcctaacac agctacaact gatgtagttt gtatccctat aatacctaag cttatcaatg
     8341 atataataga taacatagat atatatattc catatacaat aaaattattt acacctttac
     8401 tcattccata tttgattaga aactttgaaa ccatccttct tactatttta gatatataaa
     8461 tacctatcac aaatacaatt attgcatata taatatttgg tatattatca ctaaaattat
     8521 cgagcatatt ttctaaagtt ctcttagtta tattgctatt tgttgaggca gtcttagcca
     8581 atgataaaaa attcattcaa ctcctcctta tgataatatt ccgttgtcct ttaactcttt
     8641 tactatagct tctatagttt cttcttttat tgcctcaatt gtatgaatat ggctacattc
     8701 tgtcagaacc gataattgtt taaattcatt tgtctcaact ttcttcataa agttgtctat
     8761 atccatttta gaataaatat taagttctgc agttatctga ccatatgttg gatgatttac
     8821 aataacatct tttataatac cacctaaatc cacaattatc tttaattcat cataaatttc
     8881 tttagaatcc ttatgatttt tacactttat ttgttttgta aaatacggtt gattatatat
     8941 tatatatcct tgaggtgtag ctattatttc aaatcctcta gctcttataa gggctatatc
     9001 ttgaactatt acttgcctac ttacatttaa tagttcagct agtgttccac cttttacagg
     9061 atgcttagat tcttttaaaa tatctattaa tttacttctt ctttcattag aattcatatt
     9121 acaccttctt tccaaataaa aactttacct atactatata attttatatt ttatcttatt
     9181 ataaatcaat attgacttta tattctattt aatcttaact tttataataa ataaaaaaag
     9241 actacgtggc tacgtcctac tctcccaggc agtttcccac caagtaccat cagcgctaga
     9301 gagcttaact tctgtgttcg gaatgggaac aggtgtatcc tctctgctat tgtaaccaca
     9361 taatctttat gcttaatatt tctattaagt ttttaataag tttatagaat ctagtaatac
     9421 tagtttcttt agagttagca ctctaaaaac tacacatata tcttaatgaa tgaacatcaa
     9481 ataaatattg gtcaagtcct cgacctatta gtatcgataa gctaaataca ttgctgcact
     9541 tacaccttcg acctatcaac cagatagtct ttctggggtc ttacccttgc ggtgggaaat
     9601 cttatcttga agttggcttc gcgcttagat gctttcagcg cttatccatt ccgtacatag
     9661 ctacccagcc atgcccttgg cag
//
LOCUS       DACTZW010000121         9592 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.122, whole genome shotgun sequence.
ACCESSION   DACTZW010000121 DACTZW010000000
VERSION     DACTZW010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9592
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.122"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            425..763
                     /locus_tag="JAM15_17390"
     CDS             425..763
                     /locus_tag="JAM15_17390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6800019.1"
                     /translation="MANIGKIIGDRIKVYRTKLGYSQEFLAEKAGLHPTYIGQIERAE
                     TNTSINIIMKIATALDIPLELLFANIITTEGVDNSVPLECYEMINKLTEKEQIAMLEL
                     IKCIIKYKEI"
     gene            785..1102
                     /locus_tag="JAM15_17395"
     CDS             785..1102
                     /locus_tag="JAM15_17395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6800020.1"
                     /translation="MNYIGKRLKEERKKANLTSKEFANMVGVSPWYITQIESGKKNPS
                     LKTFIKFVNILNISADVLIKDITSTGKTYLENDINEELKDLNSRELNLISQIIDIIKK
                     NKI"
     gene            1252..1929
                     /locus_tag="JAM15_17400"
     CDS             1252..1929
                     /locus_tag="JAM15_17400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800021.1"
                     /translation="MIVIEGSDKFKIAKEYIDVEYTLFSKVTFRYEKLKFKDNAELEK
                     IKMFKYKNGYIPNKLNLSFGYRFSSYKKQIIRETVDTLRLTEIFSSENIEDIKFIKDG
                     TKKLEISIEKVVKFKRRKKRNYVCCYCPDMYRDIKLDKESINKIYNRKIKIEREVNIF
                     EDEDVIINKKVLKFPKSWTKNMQKYWLSENKYPIHSTVIDDDRYKCCNVQYTKNRVII
                     LYYIYNH"
     gene            complement(2257..3024)
                     /locus_tag="JAM15_17405"
     CDS             complement(2257..3024)
                     /locus_tag="JAM15_17405"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HAT6800022.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKKYIIKEAKELKDACLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYIHDIPLLFTFRSVVEGGEKLISRDYYTTLN
                     KEISNTGLVDLIDVELFMGDEVIDEVVNFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKIAVMPQNEKDVLVLLEATNEMFKIYADRPIITMSMAGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELNSVLNLLHKSIN"
     gene            complement(3644..3844)
                     /locus_tag="JAM15_17410"
                     /pseudo
     CDS             complement(3644..3844)
                     /locus_tag="JAM15_17410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
     gene            3909..4046
                     /locus_tag="JAM15_17415"
     CDS             3909..4046
                     /locus_tag="JAM15_17415"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800023.1"
                     /translation="MVFQPIPFLWAEPCHTGVSLYCGTGYGKTTVPKVIHKSLYSRSL
                     D"
     gene            complement(4234..4464)
                     /locus_tag="JAM15_17420"
     CDS             complement(4234..4464)
                     /locus_tag="JAM15_17420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAT6800024.1"
                     /translation="MKPTKEVLPFTIILLAVHGDVNAINGILKHFEHYIIRLSQKTLF
                     DEYGNPYIHVEEDTKRMLGTKLITAILRFNLS"
     gene            complement(4466..4873)
                     /locus_tag="JAM15_17425"
     CDS             complement(4466..4873)
                     /locus_tag="JAM15_17425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAT6800025.1"
                     /translation="MVDEKTIEHQFDSFCKTVLRNYARDIYDENKRRNDYLVSLESLS
                     LAELSKLSILDDYDSNYICMVSYDYNIRIEDVLMAQAIGKLTKRKQDIILLSFFLNMT
                     NADIATLMDLAENTIHYHKTNALKELKELMEEH"
     gene            complement(5233..5682)
                     /locus_tag="JAM15_17430"
     CDS             complement(5233..5682)
                     /locus_tag="JAM15_17430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAT6800026.1"
                     /translation="MELIEWNYAYITDLVEFANDKEIANNLRDNFPHPYREQNARDFI
                     SFCLATPDVKQLSYAIFYQERAIGSISLTFEEDTSINKNAELGYWLARNYWGKGIATN
                     AVKEICKIAFEKYNLNKIHANVYSYNRESSKVLEKCGFKIEEYCHNS"
     gene            complement(5696..6622)
                     /locus_tag="JAM15_17435"
     CDS             complement(5696..6622)
                     /locus_tag="JAM15_17435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800027.1"
                     /translation="MSDILSRITNKIGDKNIVDKLSALSKSDLNSLLLEVFDRQANTL
                     TATDILKSYQLNRFTIPSSIDPEEIHALESKLLRKAFNMDIKTIMLSPSAPLGSCSVF
                     GSVDQYNVVSALRGTETLADPSNMLAIIIADKLKRKEENNTIPIHMATTARAIRAQNF
                     VGKGLYSHFGLYCMVSSGIDTGSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRN
                     GYKDNDGFFDRMVETIKLIFPNIELSIHNDDVDNNYYKGINFKISVKQGNETVEIVDG
                     GFVDWTYQMLGNKKERCLISGIGLERFLVAVS"
     gene            complement(6747..7529)
                     /locus_tag="JAM15_17440"
     CDS             complement(6747..7529)
                     /locus_tag="JAM15_17440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="HAT6800028.1"
                     /translation="MTKTQQEMIQNVLEFSKRDSRIIGLAISGSYITKSLDEYSDLDF
                     LIVADDKSYEEVIEERLLIVEQFGTLVSAFTGEHVGEPRLIISLYDSPVLHVDFKFTT
                     LDGLLDRVEDSAILYEENNCITEIYSKKEAYFPTPDLQWIEDRFWIWVHYACTKIGRR
                     ELFETIDFLSFLRQSVLSPLIQLLLGKLPRGVRKIELDAPQYIEALEKTVANHEYESC
                     VNALQATINLYLELREELSQSPIVRKVEAERVALQYFQDLIK"
     gene            complement(7685..8311)
                     /locus_tag="JAM15_17445"
     CDS             complement(7685..8311)
                     /locus_tag="JAM15_17445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAT6800029.1"
                     /translation="MNMHLIDFMNEDIKKKLVKKTYKKKETILFAEQENEYVILMIDG
                     IAEAFILNVKGNISTIHLYRSGSFFGEMEQFNDGKKPVEIVAFTDCNVYKLHRDDFLN
                     WLRGDFEATKFLIREISSKLVVNAELIEELSSLSVKERLLRCISLHYYRSELNLLTKK
                     QLASEVNAPIRSINRAINECVQEHLIAYENKRFSVINQREVLKNLPTT"
     gene            complement(8404..9222)
                     /locus_tag="JAM15_17450"
     CDS             complement(8404..9222)
                     /locus_tag="JAM15_17450"
                     /inference="COORDINATES: protein motif:HMM:NF024254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800030.1"
                     /translation="MVIVDPKAERGKWKETLPEIAHEINIVNLTSDDENKGLLDPYVI
                     LSRKKDSESLAIDILTFLTGISSRDSDKFPVLRKAIRNVTQSEQRGLLLVIDELRKED
                     TSISNSIADHIESFVDYDFAHLLFSDGNVKQSISLEKQLNIIQVADLVLPDADTSFEE
                     YTTIELLSVAMLIVISTFALDFIHTDRSIFKIVDLDEAWSFLQVAQGKTLSMKLVRAS
                     QDSQDKRIERLKNYLTENLQQLNTEMVRSYIPTSSIVNSFPSLNLLCRKMTTGK"
     gene            complement(9223..9393)
                     /locus_tag="JAM15_17455"
                     /pseudo
     CDS             complement(9223..9393)
                     /locus_tag="JAM15_17455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897383.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         3363 a         1514 c         1303 g         3412 t
ORIGIN      
        1 tatttcactt ctatataatt agatttaaaa atgtttacct taccaatata atgattaaac
       61 tcaaaaggct tattaaaaaa ttttccatgt acataaattg ttcaatatat gaaatcgaaa
      121 atttttttaa ttttcaaaac atgttgtaca tatctaatat gtaattgcaa taaaaaatgc
      181 tataattaac atattattaa ttcgttttat tattgtagta tggctatgaa attatgaaaa
      241 tatttctcta attaaaaata tgatttatcc atatttgttt attgtagata cagactatac
      301 aaaaataaat agcacttatt tcagtataaa aacatatata gtctatattt agactaaaaa
      361 agtataaata gtctatataa aacaacttaa actatgaata taatctaaag tggagggata
      421 ataattggca aatataggaa aaataatagg agatagaata aaagtctata gaacaaaatt
      481 gggatatagt caagagtttc tagcagaaaa ggcaggttta catccaacat atattggtca
      541 gattgaaaga gctgagacaa atacatctat caatattata atgaaaattg ctactgcttt
      601 agacatacca cttgaattgt tatttgcaaa tattattaca acagaaggcg ttgataactc
      661 tgtaccttta gaatgttatg aaatgattaa taaattaact gaaaaagaac aaattgcaat
      721 gctagagtta ataaagtgca tcattaaata caaagaaata taagtgaggg aaatagtaac
      781 aataatgaat tatataggta aaagacttaa agaagaacgg aaaaaagcaa atttaacttc
      841 aaaagaattt gcaaatatgg ttggagtatc gccttggtat ataactcaaa tcgaaagtgg
      901 taaaaagaat ccaagtctta aaacattcat aaaatttgta aatatattaa atatttctgc
      961 agatgttctt ataaaagata ttacttccac tggaaagaca tatttagaaa atgatataaa
     1021 tgaagagtta aaagacttaa attcaagaga actaaatctg atatcacaga ttatagacat
     1081 cataaaaaag aataaaatat aattctttat attttatata aaaaaaaagg ttatttgaaa
     1141 taaataacct ttttttgtct ttttgtgtta acattgtctt atagtgctaa tgagtactat
     1201 tagaccatgt tctatggcct tattttaata taaaacgatt ggagataggc tatgattgtg
     1261 attgaaggta gcgataaatt taagattgca aaagaatata ttgatgtaga atatactctt
     1321 tttagcaaag taacttttag gtatgaaaag ttgaaattta aagataatgc tgaattggaa
     1381 aaaattaaga tgtttaaata taaaaatggc tacatcccta ataaattaaa cctttctttt
     1441 ggatatagat tctcttctta taaaaagcaa ataattagag aaactgtaga tactttaaga
     1501 ttgacagaaa ttttttcaag cgagaacata gaagatatta aatttataaa agatggtaca
     1561 aaaaaattag aaattagcat agagaaagtt gtgaaattta aacgtcgaaa aaaaagaaat
     1621 tatgtttgtt gctattgccc tgatatgtat agagacataa aactcgacaa agaatctatc
     1681 aataagatat acaacagaaa aataaaaata gaaagagaag ttaatatttt tgaagatgag
     1741 gatgttataa taaacaaaaa agtattgaag tttccaaagt cttggacaaa gaatatgcaa
     1801 aaatattggt taagtgaaaa taagtatccc atacattcta ctgtaattga tgatgataga
     1861 tataaatgtt gtaatgtgca atatacaaaa aatagagtga taatattata ttacatatat
     1921 aaccattaat atacataatt acaaaaaaat aatgacaaat atacataata caaatatatc
     1981 ttctacttta gataaaacag ttattatgaa aacttactat ctataaataa tagaaatgct
     2041 agtataccat ctataatcta atgtctagta ggttttaatg gcatatttta aatatgccat
     2101 agttgattta taagattttc tatatcactt tcaaaataca cactaaatag ttgcttttca
     2161 gatataattg cccaatttaa attttactat ctgaaaagtt ttttatattt aatttatatc
     2221 ttcaaaaata ccgtctaata tttctatata attaatttaa ttaatactct tatgtaatag
     2281 attaagtact gaatttaact ctttaaatga tatttgccct ggtgctgaaa cactttttgc
     2341 agctccaaaa gtcaatgcag aaccaaatat ttcaccacac aatctactta taacacccat
     2401 tcctgccatt gacattgtta ttattggtct atctgcataa attttaaaca tttcatttgt
     2461 agcttcaagt agcactaaca catctttttc attttgcggc ataacagcta ttttgggtaa
     2521 atctgcgccc aattcctgca ttctacataa acgagataca atctcttctt tttttggagt
     2581 tttattaaaa tcatgattag atataattac tttcacttct tttttatgag caaaattaac
     2641 tacttcatct atgacctcat ctcccataaa taactctaca tctattaaat ctactaaacc
     2701 tgtattagaa atttctttat tcaaagtagt ataataatct cttgatatta atttttctcc
     2761 cccttctact acacttctaa atgtgaataa taaagggata tcatgtatat aacttcttaa
     2821 ttcatagaga acttccttaa cttctttaat attttctaca ttctcaaaaa aatcaactcg
     2881 ccactctata atatccaaac atgcatcttt taactcttta gcctctttta taatatattt
     2941 tttatttttc ccaataattg gtacacaaat tttaggtcta ccttctccaa tagtaatatt
     3001 ttttacttga acttttcttt tcatattctc ctccataatc agaaattcta taggacttta
     3061 aattctattt tctgcataat ttaattatac attaaaaata ctatacatta taaaaatact
     3121 aatttaaaaa taatttttat tctaattctt aaaacaatcc cacatatttt agaaaaggta
     3181 ctctataata tacaaacact tcttttttac ctaaatttat tttaacattc tataattttc
     3241 acaatattct ttaaatttta ctcatataaa caatattatt ctggatgcta atagaattaa
     3301 tctataaatc atagtataat tatgcagaaa taactcgaat ttcactactt atgaagagat
     3361 tgaatattaa tgaatctaaa tcatttgcat tacttaagag ttttgactaa agttgaacac
     3421 catacaaaag tagctactca attgtttatg ccccaaccaa gcttaagtaa tgttatatag
     3481 attctcgaaa aagaatttgg tatcttttta tttgaaaaac ttatattaaa tttgattatc
     3541 ttttcataag ttggtaaatg tcgatatatc ctgtatctac aaggagtatc ggcattttct
     3601 ttttggaaga tactttgcat aagttggtat ttaaccgtat aaggataacg tcaagtgtat
     3661 caacgatttt ctcaaattgt tttctcttta tttgaatgcg attgccattc ataatgaccc
     3721 agctagaatc aaggttttca tcagcaagtt tacgtaattt tttctctcca atacgaaagt
     3781 attttgacgc ttcttcaatc gtcaaggtat atttttccca aataggtaca tcagtattgt
     3841 tcatagaatg tatcactcct ttctatgttc gtagttcaga agtagataga tggctttggt
     3901 aagctccatt ggtatttcaa ccaatcccat tcttatgggc agaaccatgt catacaggtg
     3961 tatcattata ctgtggtaca ggttacggca aaacaaccgt tccaaaggtt attcacaaat
     4021 cactatatag tcgctctctt gattaaggtc atggcgtata gtatttgttg gctatctgta
     4081 tcacaaacgt atctatctac tttattcagt tgtcaaagaa cagtcggcat tgatttgcct
     4141 ataaaagatc acaatagctt gtgggctttt atagacaaat aattagtgat tctccatgta
     4201 ccaaatagct tgatacatgg agagagggcg agattaagac aaattaaatc tcaaaatagc
     4261 agtgattagt tttgttccta gcattcgctt tgtgtcttct tctacatgaa tatagggatt
     4321 tccgtattca tcaaataaag ttttctgtga aagacgaatg atatagtgtt caaaatgttt
     4381 aagtattccg tttattgcat ttacatcgcc atgtacagca agtaaaataa ttgtaaaagg
     4441 taatacttct ttagtaggtt tcatttcaat gttcctccat gagttctttc aactctttta
     4501 gtgcatttgt tttgtgataa tgtatggtat tttctgctaa atccatcaat gttgctatgt
     4561 cagcatttgt catgttgaga aagaatgaaa gtagaattat atcttgtttt ctttttgtaa
     4621 gtttcccgat tgcttgcgcc attaatacat cttcaattcg tatgttgtag tcgtaagaaa
     4681 ccatacagat gtagttagaa tcataatcat ctaaaatact caatttactt aattctgcaa
     4741 gtgacaaaga ttcgagagat accaaataat catttctgcg tttattttcg tcataaatat
     4801 ctctagcata gttacgcaaa actgttttac agaaactgtc gaattgatgt tcaattgtct
     4861 tttcatcaac cataagattt caccctcttt ccatcgcaag gagttaaata accttgctta
     4921 ctcctatcac ggtgagaggc cgttaaatct tcgataaatt tcaaaaaaaa gagaaaaaaa
     4981 tacacactct gcctatatgg caaaaatgtg tattctttaa aacgtattta atttatattg
     5041 gttgtaagcc accaccatat tgatgtatgg aaatatgcat tggctagctt ttcataaaaa
     5101 tacaaagatg cataagaaat taatagaggg gaaaaactta ttctgttatt aaaaagtagg
     5161 ttaattctaa taaatgctat tgcggtcgaa ttaaactata tacatggcaa tcaatcatgt
     5221 ttctattctt tattatgaat tgtgacagta ttcttcaatc ttaaaaccac atttttccaa
     5281 tactttactt gactctctat tgtaggaata tacattagca tgaattttgt taaggttgta
     5341 tttttcaaag gcaattttgc atatttcttt tactgcattt gttgctatcc ctttgcccca
     5401 atagttccta gcaagccagt aacctaattc agcattttta ttaatagagg tatcttcttc
     5461 aaatgttagg ctgatacttc caatagccct ttcttgataa aaaatagcat agctaagttg
     5521 tttaacatct ggagttgcca aacaaaaact aataaaatct ctagcgtttt gctccctata
     5581 agggtggggg aagttgtcac gaagattgtt tgcaatttct ttatcattcg caaactcaac
     5641 taaatcggta atataagcat aattccactc tataagttcc atttttcttc tccttttatg
     5701 aaacagctac aagaaatctt tctaagccaa taccacttat caaacagcgt tcttttttat
     5761 ttccaagcat ttgataagtc cagtcaacaa atccaccgtc aactatttca acggtttcat
     5821 ttccttgttt gaccgatatt ttgaaattga tacctttata ataattatta tcaacatcat
     5881 cattatgaat tgataactct atattaggaa aaataagttt gatagtttca accattctgt
     5941 cgaaaaatcc gtcattatct ttgtatccgt ttcttttgcg tagaataata gagaaacgaa
     6001 cattttctat ttcacttaat atatctttat aatagttcaa gtgcttttct aacaacattt
     6061 tttcacaagt gtaagaccct gtatctatac cagatgaaac catacaatat aagccaaaat
     6121 gtgaatataa acctttacct acaaaatttt gtgctcttat tgccctagca gtagtagcca
     6181 tgtggatagg tatggtatta ttttcttctt ttctttttaa tttatcagca ataattattg
     6241 ccaacatatt tgaggggtct gcaagtgttt ctgtccctcg tagagcactt actacgttat
     6301 attgatctac ggagccaaaa acgctacagc tacctaatgg agcagaggga gaaagcataa
     6361 tcgtcttgat atccatattg aatgcttttc tcaataattt tgattccaaa gcatgaattt
     6421 cttctggatc tatactgcta gggatagtaa atctatttag ttggtatgac tttagaatat
     6481 cagttgcagt taaagtattt gcttgtctat caaacacttc taatagaagt gagttcaaat
     6541 ctgattttga tagagctgat aacttatcaa ctatattctt atccccaatt ttatttgtaa
     6601 ttctacttaa aatatcactc atagttatcc tccatactgt tactttcaaa ataattataa
     6661 aatggttata acaactaatc taggtcattt gaccaaaaat gaaaaaacac tgaatattta
     6721 ctattcaata tttttttact ttgggtttat ttgattaaat cttgaaaata ctgtaatgca
     6781 accctttcag cttcaacctt tcggacaata ggactttgtg ataattcctc tcttaactca
     6841 agatacaggt tgatagtagc ctgcaatgca ttaacacagc tttcatattc atggttagca
     6901 accgtctttt ctaatgcttc aatatattgg ggtgcgtcca attcaatttt tctaactcca
     6961 cgaggtaatt tacctaagag aagctgtatt aatggggaaa gtactgattg tcttaaaaaa
     7021 gataaaaaat caattgtttc aaatagttct ctacgtccaa tcttagtgca agcgtaatga
     7081 acccaaatcc aaaatctatc ttcaatccac tgtaagtctg gagttgggaa gtatgcttct
     7141 tttttagaat aaatttctgt tatgcagttg ttttcttcat agagaatagc tgaatcttca
     7201 accctatcta gtaaaccatc taaggttgta aacttaaaat caacatgaag aacaggggaa
     7261 tcatagaggg aaattatcaa tcgaggttct ccaacgtgtt cgccagtaaa agcagaaact
     7321 aatgtcccaa actgttccac aataagtaat ctctcttcga taacttcttc ataggattta
     7381 tcatctgcta caatcagaaa atccaaatca gaatattcat ctaacgattt tgtgatataa
     7441 gaaccgctaa ttgcaagtcc tattatccta ctatctcttt ttgaaaattc taatacgttt
     7501 tgtatcattt cctgttgtgt tttagtcata atataacacc tctcactttc ttttattagc
     7561 tatcaatcca acataattat gcataggagt attatataat gaagaaataa aaaaaaatag
     7621 gtcacttgac ccgaaataaa aaggtattga ataattatta tccaatactt ttttgaaatt
     7681 atacttatgt tgtaggaaga ttctttaata cctctcgctg attaattaca ctaaatcttt
     7741 tgttttcata agcaattaga tgttcttgta cacattcatt tatagcacga ttaatgcttc
     7801 taattggagc gtttacttcg ctagcaagct gttttttggt aagcagattt aattcacttc
     7861 tataatagtg taaggatata cacctcagaa gtcgttcttt aacacttaaa gatgataatt
     7921 cttcaattaa ttcagcattt acaactaatt tactagatat ttctcgaatc agaaattttg
     7981 tagcttcaaa atctcccctt aaccagttta aaaaatcatc tctatgaagt ttatatacat
     8041 tacaatctgt gaaagcgaca atttcaacgg gttttttccc atcattaaat tgttccattt
     8101 ctccaaaaaa actaccactt ctataaagat gaatagttga gatgtttcct ttcacattta
     8161 agatgaatgc ttctgcaata ccatcaatca taagaattac atattcattt tcttgctcag
     8221 caaaaagaat agtctctttc tttttatacg tttttttaac aagcttcttt ttaatatctt
     8281 cattcataaa atcaattaaa tgcatattca tccctcctta ccaaatcttt gattaaatta
     8341 tatcatcttt caattagtta ggtaagataa taaaaatata tttacataga aactattcca
     8401 ttattatttt ccagttgtca tttttctgca aagtaagttc aaactgggaa agctgttgac
     8461 aatagaacta gtaggaatat acgagcgaac catttcagta ttcaactgtt gtaggttttc
     8521 agtcagataa ttcttcaaac gttcaattcg tttgtcctgt gaatcttgcg atgctctaac
     8581 cagtttcata gatagcgttt taccttgtgc cacctgcaaa aaagaccatg cttcgtcaag
     8641 gtcaactatc ttgaagatag agcggtcagt atgaataaag tctaatgcaa aggtactaat
     8701 aacaatcaac atagcaacac taagaagttc tattgttgta tattcttcaa agctagtgtc
     8761 ggcatctggc aatacgaggt cagcaacttg aataatgttc agctgtttct ccaagctgat
     8821 agactgcttc acatttccgt cactaaacag tagatgtgca aaatcatagt ctacaaaact
     8881 ttcgatatgg tcggctatgc tgttactgat agaagtatct tcttttcgta attcatcaat
     8941 gacaagtaat aaccctcgct gttcactttg ggttacattg cggattgctt ttctaagcac
     9001 tgggaactta tcactgtcac gactggagat accagtaagg aatgttagga tatcaatcgc
     9061 taaactttca gaatcctttt tacggctcaa aatgacgtaa gggtcaagca atcctttgtt
     9121 ttcatcatca ctggttaaat tgacaatgtt tatctcatgg gctatttctg gtagcgtttc
     9181 tttccatttg ccacgttctg ctttagggtc aactatgacc acctatccgc cgaatagtac
     9241 cgcatagtaa acaagcatat tgttactgaa tgatttacca ccacccaatg aaccgataaa
     9301 cgcagacgct aacacattgg taatagaacc ctttacccct tgactagcaa gggcaggttt
     9361 tagatagaca ttctttccag tgtccagatt gtatattcta ttgttggagg agtacctgca
     9421 aaaattataa aaaagagatt taataatgat acaatttcaa aattattaga aattaaatgg
     9481 tgggattggc catataaaaa aattcaatca aacattaagc atattcaatc aggaaatatt
     9541 gataaattag tttaatattt tataatttat ttatattaaa ctttacttta at
//
LOCUS       DACTZW010000122         9561 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.123, whole genome shotgun sequence.
ACCESSION   DACTZW010000122 DACTZW010000000
VERSION     DACTZW010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9561)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9561)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9561
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.123"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            230..1309
                     /locus_tag="JAM15_17460"
     CDS             230..1309
                     /locus_tag="JAM15_17460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800031.1"
                     /translation="MPELLKNMYNRESLYEVAVAIQSVYNSFKVDEFIKSTMDETWNN
                     LELKARCRKISMSLGMYLPEDYKEALSILEKSVTGFYFAFFFPDFVEVYGQDEINWDL
                     SISALERNTEYWSSEFAVRAFIIKDEERMMAQMRKWSKHKNEHIRRLASEGCRPQLPW
                     GQAISKFKKDPTPVLPILEQLKTDTSTYVQKSVANNLNDISKTHPDLVISIAKDWYGK
                     NKSTNWIVKHGCRTLLKKGNRDVLALFGYDDTTSINIQDFTLETTSISIGENLTFSFK
                     ILAKKATKTRLEYGIDYMKSNGKRNRKIFKISEVSLKENEKKSYMKKHSFADVSVRRH
                     YPGIHSITIIINGVEKGKLDFELGV"
     gene            1663..2001
                     /locus_tag="JAM15_17465"
     CDS             1663..2001
                     /locus_tag="JAM15_17465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016286587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HAT6800032.1"
                     /translation="MAQDAVKIRKYFHEDAYINWHDTNEHFTLEEFIIANCDYPDKWN
                     GKVERVLEFGNLVITVTHVYAINKPLSFHVVSFISLKDDKIISIDEYWGEDDDVPQWR
                     LDKHIGKPIK"
     gene            2118..2921
                     /locus_tag="JAM15_17470"
     CDS             2118..2921
                     /locus_tag="JAM15_17470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAT6800033.1"
                     /translation="MEEKYILSDRGKVYYWIKESNSVFAKNLIFLPGLTANHHLFDFQ
                     IQYFSKNHNVLVWDAPAHGKSRPYLDFSYSNLVEELKVILDRQNMKKVVLIGQSAGGF
                     VAQSFIVKYPNMVEGLMMIGTCPYGTDYYSKSDIFWLKQTEWMLKLFPDKLLRNIISK
                     MCGATSEGRRSMMKMLEGYEKKELCHLMYLGFAGFIPEIQDLNIHCPVCLVVGDKDKT
                     GKVRKYNEQWHNKTGYPLHIIKNASHNVNVDKPNELNQIMDIFIKQLNI"
     gene            3308..4198
                     /locus_tag="JAM15_17475"
     CDS             3308..4198
                     /locus_tag="JAM15_17475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HAT6800034.1"
                     /translation="MIESIPAKQILQKVKFDNTRWFGIDYNMNLYRGCSHGCIYCDSR
                     STIYNIENFDKIRYKENVIEILSKELRSKRKKGVVGIGAMSDTYNPFEKQLCITKQAL
                     DLISENHFGVSIDTKSSLVVRDIPILQKIKKNNSAIVKLTITTANDELSKKIEPYVNP
                     SSVRFEAVKELNDSGIFCGILLTPMLPFLTDNKDEIRAIVEKAHKANAKFIYCMYGVT
                     MRSGQREFFYEHLRDISPKLVLKYQKTYGLNYVCTVQNKDSCEKLLREECARYGILTD
                     MKDIIKAYKRSESYTQIKFF"
     gene            4912..5355
                     /locus_tag="JAM15_17480"
     CDS             4912..5355
                     /locus_tag="JAM15_17480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAT6800035.1"
                     /translation="MIEIKTIEINKKSQIDLLMLADPCEEMIDKYLNKGTMHALYDNK
                     ELTCIAVVNEISKEICELKNIATYEHFQNMGHASKMIYHLLDVYSKKYSSMVVGTSES
                     GVPFYEKFGFVYSHKIKNFFVDNYPEPIFEGELQCVDMLYLSYNF"
     gene            6070..7191
                     /locus_tag="JAM15_17485"
     CDS             6070..7191
                     /locus_tag="JAM15_17485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HAT6800036.1"
                     /translation="MKEKLEEKSKIIKTSKEYKRTIIEEKDREWTKKLNDILSRGDFS
                     NEKLDKIKDLIPKEILTSENVGEVVTEDGYAKPEYDEVFKSLFTLNNDYDLLANFIND
                     ILKDAPYANRNIKQFTQIKRIIKVETDPTINYIGEKRPRLDILAEDEERNHINIEMQR
                     ALEEDYLERAEYYLSRVHGRKLEEGKEYKEIGKTVGIHILNHVKYNHIEDYVNCLRLT
                     MDGHPDIYSSKTALYFIELPKIRKSSCIANRVLIWGKLIDNPSHIDIRILSKTDYVIK
                     RALDRLKELGSNEDYLLNLKRGAYIMNKSRNFKEEIFQEGIEKGIEKGIEKGIAKGKR
                     EEKFNIIIKLKNKGYNLSEICDIIDDLNKSEVEKVYNQN"
     gene            7396..7884
                     /locus_tag="JAM15_17490"
     CDS             7396..7884
                     /locus_tag="JAM15_17490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3841 domain-containing protein"
                     /protein_id="HAT6800037.1"
                     /translation="MKFYTIQTLEFWNNNKNNKYLSNDYSFILEDFDIPYKWMYSQMT
                     NRIYEFDDSMIWVWTKRPDLRCSGYLEKGKKGVLLEIKISEDNVLLSEFDLWHLPLMD
                     IAVELYEDEQIEKKVSWERIFDLELCSKLNEVNIEDLTLQGVTSKVPLSNVKLIKEFV
                     AK"
     gene            7970..8377
                     /locus_tag="JAM15_17495"
     CDS             7970..8377
                     /locus_tag="JAM15_17495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800038.1"
                     /translation="MSKQQTGIKSTLISEILGISYCIGATLVNKYFFKGSSIEYLPII
                     IWVLAMGAQWVYNKKYDDLIDEASKCILSRVNDIAIKVLFFSVAIVSIFLVTLDINVS
                     NLNIGMSLLVILFIQSLLKLILFIYFDRKGIYN"
     gene            8378..8596
                     /locus_tag="JAM15_17500"
     CDS             8378..8596
                     /locus_tag="JAM15_17500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6800039.1"
                     /translation="MSVLLKTKIKSYREKNLMTQGELAKSVGVRRETIVHLENGRYNP
                     SLKLAMDIAKVFDTTVEELFEFIEENNI"
BASE COUNT         3830 a          926 c         1660 g         3145 t
ORIGIN      
        1 agtaaagtat aaaattctat tactataata aaagatagaa ctagaagtct ttatgaaagt
       61 gggaaaagta tttatataaa taaatttata tggtttatag tttaacagta ggaaatatcg
      121 tatgagtgag aatatcgtat tttacataaa gatttagcaa tatgacacac tgttgtcgtg
      181 ttctgtagga tatgattaat aaatcagata tgaaaggaga gtgagtaata tgccagaatt
      241 actaaaaaat atgtataatc gtgagtcact ttatgaagtt gcagtagcta tccaatcagt
      301 ttacaactca tttaaggtag acgagttcat aaaatctaca atggatgaga catggaataa
      361 cttagaatta aaagccagat gtcgaaagat aagtatgagt ttaggaatgt atttaccaga
      421 agactataag gaagctcttt ccattcttga aaaatcagtt acaggttttt attttgcttt
      481 tttctttcca gattttgttg aagtttatgg gcaggacgaa ataaattggg atttatctat
      541 aagtgcacta gaaagaaata ctgagtattg gtcttcagaa tttgctgtaa gagcatttat
      601 catcaaggat gaagagcgta tgatggcaca gatgcgtaaa tggtctaagc ataaaaacga
      661 acatatacga agacttgcaa gtgaaggctg tcgtccccag ttgccttggg gacaagcaat
      721 atccaaattt aaaaaagacc ctacacctgt actgcctata ttggagcaac ttaaaacaga
      781 tacatcaacg tatgtacaaa agagtgttgc taataatcta aacgatatct caaaaacaca
      841 tccagattta gtcataagca ttgcaaagga ttggtacggt aaaaataaat ccactaactg
      901 gattgtaaag catggttgca gaactctgct aaaaaaagga aatcgtgatg tattagccct
      961 ttttggatat gatgatacta cttcaataaa tattcaggac tttactttag aaacaacgtc
     1021 tatttctatt ggagagaatt taactttttc atttaagatt ttagcaaaaa aagcgacaaa
     1081 aacaaggctc gagtacggaa ttgattatat gaaatctaat ggaaaaagga ataggaagat
     1141 atttaaaata tcggaggttt cattaaaaga aaatgagaaa aagtcatata tgaaaaaaca
     1201 ttcatttgca gatgtaagtg taaggagaca ttatccaggt atccactcga ttactattat
     1261 tattaatggg gtagaaaaag gcaaacttga ttttgaatta ggtgtataat tttactaaca
     1321 gcataaccta tatcagatac tttgctaaac ctatatcgta tactctaata aatctatatt
     1381 aggtagttta ctacttgttt actgaattta aatacaaaga aatacaggtg ttaatccctg
     1441 cccattaaag gaatatgagc ataacacaaa agtagaactt atcaattctg ttacgggtat
     1501 agtagtaaat ccatagaatc acaattagaa gatgaagtgt aaaaaataag ttagtgttga
     1561 ttttagttgc tagtgatatt ggatagttat acaatagcca tataaattag aatttgtaga
     1621 ggagaaatgt aaatggatgt atatagtttt tgaaatgaca ctttggcaca agatgctgtt
     1681 aagataagaa aatattttca tgaagatgct tatattaatt ggcatgatac aaatgagcac
     1741 tttactttag aagaatttat tattgcaaat tgtgattatc ctgataaatg gaatggtaaa
     1801 gtagaaaggg tgctagaatt tggaaattta gtaattacag tgacacatgt ttatgcaata
     1861 aataaaccac tatcatttca tgtcgtttca tttatcagtc ttaaagatga taagattatt
     1921 tctattgatg aatattgggg agaggatgat gatgtgccac agtggagatt agataaacat
     1981 attggaaagc caataaaata gcgtttgttc tgttttataa ctgaaatttt gataacattt
     2041 gatattttga tttgtcattg gtcaacatag tcgttagtgt aataatttaa aaaagtagaa
     2101 tttggagagt gagcactatg gaagaaaaat acatcttatc tgaccgaggt aaagtatatt
     2161 attggataaa agaaagtaat agtgtgtttg caaagaactt aatttttttg ccaggactaa
     2221 cagcaaatca tcatcttttt gatttccaga tacagtactt ttcaaaaaat cataatgtat
     2281 tggtatggga cgctcctgct catggaaaat caagacctta cttagatttc tcatattcta
     2341 acttggtaga agaattgaaa gtaattttag atagacaaaa tatgaaaaag gttgtactta
     2401 tagggcaatc ggcaggggga tttgtggcac agtcctttat tgtaaaatat ccaaatatgg
     2461 tagaaggatt aatgatgatt ggaacttgtc catatggaac tgattattat agtaagtcag
     2521 atattttctg gttaaaacag actgaatgga tgttaaagtt attcccagat aaattgttgc
     2581 gaaacataat atctaagatg tgtggagcta cgtctgaagg cagaaggagt atgatgaaaa
     2641 tgttagaagg ctacgaaaaa aaagaactgt gtcatctcat gtatctggga tttgctgggt
     2701 tcataccaga aattcaagac ttaaatatac attgtccagt ttgtttggtg gttggagata
     2761 aagacaagac gggtaaagtg agaaaatata atgagcagtg gcacaataag actgggtatc
     2821 cattgcacat tataaaaaat gcttcacata atgtaaatgt cgataaacct aatgaactaa
     2881 atcagattat ggatatattt attaagcaat taaatatata aaaattacat acccattagg
     2941 taaattatgt agtatatgtg tttatagatg gttatagaaa taaatatgta ataaactact
     3001 taacacttaa aaagtggatt tgtccagagc ataatacaaa gcatgatata tataaatttt
     3061 taagcgaaat acatcaaaag aaggattaga attagtggag ataaaacagc tattagagat
     3121 tataaataaa tagttttaaa ggtactacga atatagagga aggtaaatca tacgttattc
     3181 aaggattata aatgattagt ttaaaagtac tatcggatag gtctctgcat atttaaacct
     3241 tagtaaaggt agttaaagta gtagtttaaa aactaaaaaa ttatataaag gaattaggta
     3301 taagaaaatg attgagagta taccagcaaa acaaatttta caaaaagtga aatttgacaa
     3361 tacaagatgg tttggaattg actataatat gaatctctat cgtggttgtt ctcatggatg
     3421 tatatattgt gatagccgca gcacaatata caacatagag aattttgaca aaattagata
     3481 taaagaaaat gtgatagaaa ttttaagtaa agaattgcgt tcaaaaagaa aaaaaggggt
     3541 agtaggcatt ggagctatgt ctgacacata taatcctttt gaaaagcaac tttgtattac
     3601 aaagcaggca ctagatttga tttcggaaaa tcattttgga gtgtctattg atactaaaag
     3661 tagtttggtg gttagagata taccgatttt gcagaaaatt aaaaaaaata attctgctat
     3721 tgtaaagttg actataacca ctgcaaatga tgaattatca aagaaaatag aaccttatgt
     3781 aaatccaagt tctgtacgat ttgaggcagt gaaagaactt aatgattctg gaattttttg
     3841 tggtatatta ttgactccta tgcttccatt tttgactgat aataaagatg aaatacgagc
     3901 aattgtagaa aaagcacaca aggctaatgc aaaatttatt tattgcatgt atggtgtaac
     3961 aatgcgtagt ggtcagagag agttttttta tgagcattta agagatatat caccaaaatt
     4021 ggtacttaaa tatcagaaaa catatggttt aaactatgta tgtactgtac aaaataaaga
     4081 ttcttgtgag aagttgttaa gagaagaatg tgcacgttat ggtattttga cggatatgaa
     4141 agatattata aaagcgtaca agaggtcgga gtcatatact caaataaaat ttttttaaga
     4201 taggctttgg atgagatata atagtggtga ttgatgtgtt gatattatag ttgattgtta
     4261 gagaggatat tatagatgaa tattagtatt aatattttag gtaattgcta gagctgatat
     4321 tatagatgaa tattaatatt gatattctag gtaattgcta gagctgatat tatagatgaa
     4381 tattaatatt gatattctag gtaattgcta gagttagtat tatagatgaa tattagtatt
     4441 gatattttag gtaactgcta gagctaatat tatagatgaa tattagtatt gatattctag
     4501 gtaattgcta gagttagtat tatagatgaa tattagtatt gatattctag gtaactgcta
     4561 gagctaatat tatagatgaa tattagtatt gatattctag gtaattgcta gagctaatat
     4621 tatagataaa tattagtatt gatattctag gtaattgcta gagctgatat tataatttat
     4681 tattagtatt gatattctag gtaactgcta gagctgatat tatagatgaa tattagtatt
     4741 gatattctag gtaattgcta gagctgatat tataatttat tattagtatt aatattctag
     4801 ggaattatca ctatatttta aaaaagtaaa aatatatatc aaaatgaatt aaataagtac
     4861 tgtaagaagt ttgttaaatt aaggtttgaa taaagtgagg gtggagaact tatgatagaa
     4921 ataaaaacta tagaaataaa taaaaaaagt caaattgacc ttttaatgtt agccgaccca
     4981 tgtgaagaaa tgattgataa atatctcaat aaaggaacta tgcacgcatt gtatgataat
     5041 aaagaactta cttgtatagc agttgtaaat gaaatttcca aagaaatatg tgaattaaaa
     5101 aacattgcta catatgagca ttttcaaaat atgggtcatg cctcaaagat gatttatcat
     5161 cttttagatg tttatagtaa aaaatattca tcaatggttg ttggtacatc tgaaagcgga
     5221 gttccttttt atgagaagtt tggatttgtt tattcacata aaattaaaaa cttttttgta
     5281 gataattatc cagaaccaat ctttgaagga gaattacaat gtgttgacat gttgtatcta
     5341 tcatataact tttagatagg ataatatttt taggttaata tacataattt attcatataa
     5401 ttatcggaat tataatttat aaattatgta taataagagt ataatttatt tagaagctgt
     5461 tatattgtat tagattcaaa taagatatat aataacttgt ttattttgaa ttttggagga
     5521 ttaattatgg attcaaataa taatactata aaatcaactg ttaaaaaggg tatttctttt
     5581 ggttcttgtt tagcaatgat tatttcttat actgcatgga aatctattcc atgggctatt
     5641 tttcatggct taatgagttg gatatatgta ctttattatt gggttaagta tgcatagatt
     5701 aaattaataa ataagtatgc aatattgtga agtttaagaa acaaaacgta agtgagtgtc
     5761 tcgaagtgaa cttttagttt ataaggcact cttttttgta ttaaataaga tatattttca
     5821 ttacttaaac aatgaaaaag atgagtatct ctattttaat acataccctt atattcattc
     5881 atttatcaac aatagtttta aaaagaaagc tatctaaaat ctattgtaat ctaagtgctt
     5941 ctctttaaag tcttaacttt agtaatgata tataagttta taaggttctt atttcaataa
     6001 tgcaaacttt acttagaagt tcagactttg gtatgaagaa atgggtaata ataaaaaaga
     6061 ggtgttgata tgaaagaaaa attagaagaa aaatctaaga ttattaaaac atcaaaagag
     6121 tataaacgaa ctataattga agaaaaggac agagaatgga ccaaaaaatt aaatgacata
     6181 cttagtagag gtgatttttc taatgaaaaa ttagataaaa tcaaggattt aattccaaaa
     6241 gaaatattga ctagtgaaaa tgttggagaa gttgtaactg aagatgggta tgctaagcct
     6301 gagtatgatg aggtatttaa atcattgttt actttaaata atgattacga tttacttgca
     6361 aattttataa atgatatcct caaagatgct ccatatgcta ataggaatat caaacagttc
     6421 actcaaataa aaagaataat taaggttgaa accgacccaa caattaatta cattggtgag
     6481 aaaagaccta gacttgatat tttggctgaa gatgaagaac gtaaccatat aaatattgag
     6541 atgcaaagag ctcttgaaga ggattatttg gaaagagctg aatattatct tagtcgtgta
     6601 catggtagaa agttagaaga aggtaaagaa tataaagaaa ttggaaaaac tgttggaata
     6661 catatactaa atcatgtaaa atataatcac atagaagatt atgtaaattg cctgagatta
     6721 acaatggacg ggcatccaga tatttattct agtaaaactg cattatattt tatagaactt
     6781 ccaaaaattc gtaaatccag ttgtatagca aacagagttc taatatgggg caaacttatt
     6841 gataatcctt ctcatatcga tattagaata ctatctaaaa cggattatgt tattaaaaga
     6901 gcacttgata gattaaaaga attaggtagt aatgaggact atttattaaa tttaaagaga
     6961 ggtgcgtata ttatgaataa aagtagaaat tttaaagaag aaatttttca agaaggtatt
     7021 gaaaaaggta tcgaaaaagg tatcgaaaaa ggtattgcaa aagggaaaag agaagagaaa
     7081 tttaatatca tcataaaatt aaaaaataaa ggatacaatt tgagtgaaat atgcgatatt
     7141 atagatgatt tgaataaatc agaggttgaa aaagtctata atcaaaacta atactatgat
     7201 tgagatggca ctagataaat acaaagcttc ctcttttaaa tttaaattaa tataaaactt
     7261 tgttatttaa atatggtaga tataaagaga tatataaata ataggtacaa agaggtgtat
     7321 aaataaagga gataattcaa aataaaagtt tgaaccatct ccttcttata gaaaaacaaa
     7381 ggggttgatt tatatatgaa attttatact atacagactt tagaattttg gaataacaat
     7441 aaaaacaata aatatctatc aaatgattat tcttttatat tagaagactt tgatattcca
     7501 tacaaatgga tgtatagtca aatgacaaat agaatatatg aatttgatga tagtatgata
     7561 tgggtttgga cgaagagacc tgatttaaga tgtagtggtt atttagaaaa aggaaaaaaa
     7621 ggtgttttac ttgaaataaa aataagtgaa gacaatgtgt tattatcaga atttgattta
     7681 tggcatttac ctttaatgga tattgctgta gagctttatg aagatgaaca aattgaaaag
     7741 aaggtaagtt gggaaagaat atttgactta gaactgtgtt caaaattaaa tgaagttaat
     7801 atagaagatt tgacattgca aggagtgaca tctaaagtgc ctctatctaa tgtaaaatta
     7861 ataaaagaat ttgttgcaaa ataatatttt tattgaaatt tattcaaaaa agttatatat
     7921 ttataacaag aggtgttata aatacataac tttttaaggg ggattttata tgtctaaaca
     7981 acaaactggt attaaatcaa cacttatttc agaaatattg ggaatttctt attgtattgg
     8041 agctacatta gtaaataagt atttttttaa aggaagtagt attgaatatc ttcctataat
     8101 tatttgggta ttagctatgg gagctcagtg ggtctataat aaaaagtatg atgatttaat
     8161 tgatgaggca tcaaaatgta tactatcaag agttaatgat attgcaataa aagtattgtt
     8221 tttttctgta gctatagtat ctatatttct tgtaactttg gacataaatg tgtcaaattt
     8281 aaatatagga atgtctttat tagtcatttt gtttattcaa tccttgttga agttaattct
     8341 atttatatat tttgacagaa aggggatata caattaggtg tcagtattac taaagacaaa
     8401 aattaaatcc tatagagaaa agaaccttat gacacaaggt gaacttgcaa agtcagtagg
     8461 agtaagacgt gaaactattg tacatttaga aaatggtcgc tacaatcctt ctttaaaact
     8521 ggcaatggat attgctaagg tatttgatac aactgtagaa gagttgtttg aatttattga
     8581 agaaaataat atttaaattt catgtattac ttatgcatta gagaatgaat taatagataa
     8641 aaaattcaag tttatgtatt agagaatgaa ttaattatag gtaaaaaacc aagcttatag
     8701 attagagaat aaatgactta tagatgaaaa accaagctca tagattaaag aatgaatgat
     8761 ttatagatga aaaagaaagc ttatagatta gagaatgaat taattatagg taaaaaacaa
     8821 gctaatagat taaaaaatga atgatttata gattaagaag taagcttata gattagagaa
     8881 taaatgactt ataaataaaa agaaagctta tagattagag aatgaattaa ttataggtaa
     8941 aaaacaagct tatagattag agaataaatg acttataaat aaaaaccaag cttatagatt
     9001 agagaatgaa ttaattataa ataaaaacca agcttataga ttagagaatg aattaattat
     9061 aaataaaaac caagcttata gattagagaa tgaattaatt ataggtaaaa accaagctta
     9121 tagattaaaa aatgaatgat ttatagatga agaactaaac ttatagatta aaaaataaat
     9181 gacttattta tagatgaaaa accaagctta tagattaaaa aatgaatgat ttatagatga
     9241 agaactaaac ttatagatta aaaaataaat gatttataga tgaagaacta aacttataga
     9301 ttaaaaaata aatgacttat agatgaaaaa tcaagctcat agattaaaga ataaataact
     9361 tattagatga aaaaccaagc ttatagataa gaagtccatg cttataagcc agaaaatgaa
     9421 tactttaata gattaaaaaa tacatatttg tgaattatag aatgaataac tccataaact
     9481 agaaaattta taataatatc tatatgaaaa ttagaattat tttatcacaa aaaaattaag
     9541 ttaaataaat atgaaattac t
//
LOCUS       DACTZW010000123         9294 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.124, whole genome shotgun sequence.
ACCESSION   DACTZW010000123 DACTZW010000000
VERSION     DACTZW010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9294
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.124"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            24..1262
                     /locus_tag="JAM15_17505"
     CDS             24..1262
                     /locus_tag="JAM15_17505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800040.1"
                     /translation="MNKGFYKLNSVVLNFDIKNDVNKIRFNHYIMRKENIQRLQGTLP
                     NGQFYMTVRRAATDLQLSISTISRLVKEFLDLGIIRLVSKGVKGNRSVYSYVSIEFNG
                     SLFDDSKYMELDCVCNDEFIDNSGIEFDCDSKDNSFNGDINVETVHCINEYFSDDDVE
                     HNYNNFHNKDTIKDKAISNISTIKKYIDESFDTNKSENSNLQQESINFNFNDTCNEID
                     KRTNNSIENNQNKRPMRLSDISVLSDKGMTNKKNYFNHNHGIQKRNKSATKKKESLNK
                     FNKKNIQQSIINMLNKKSGKNFKIDSPISIKLINERLKEGYVLEDFYKVIEVKVAKWK
                     NTIMEMYIRPETLFSYKFESYVNENISMKSQSNVHPCKEGNSNDSSNYIHSDYTTYDG
                     SVRERKKYENVRYWNPICEI"
     gene            2186..3487
                     /locus_tag="JAM15_17510"
     CDS             2186..3487
                     /locus_tag="JAM15_17510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAT6800041.1"
                     /translation="MGKSKDVEIEKSILGTILLDNKLSYKLDELNENMFMNDICLEIF
                     KIMKELKKENIVIDVATVKSKIDRKSLAIKTSDVTNLITWGQNFGLDGHIKILKENLA
                     RRSINQNCQNLLHSLNLGENIDTCIYKFESNIKEILDKDTYENDDVNSIAGKVLDFLE
                     NKKDIGFKFGIKLLDTTIGGLFKGELTTIAAKSGVGKTALALQIMLNSFKQGKKTLFI
                     SREMTSEQVFMRNICRVTGVSTRNMKSKEIDENDWKLIVNAIGDLSENNLIYINDKID
                     TISAIRKRIRQVKPDLLIVDYVQLLTSQKSMDKREREVATFSRELKNMTLDFNIPVIQ
                     LSQLNDEMKDSRPYGDRPMRDSKAIYHDSNNVVYIHQLKGSDYEEAVRDIGESEEAVR
                     ASEYRGIKMVDLIVAKCRDGQTRHKHFCYFGDKLHFQELNY"
     gene            3563..3838
                     /locus_tag="JAM15_17515"
     CDS             3563..3838
                     /locus_tag="JAM15_17515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAT6800042.1"
                     /translation="MLELTKIIELLEEHKIEVSIPKELHKYSLLEYLELCQQSGGTYF
                     YIKTLEGALKEARNELMIKLFNGKNYMELARMFEMSVINVRHIVRKK"
     gene            4888..5118
                     /locus_tag="JAM15_17520"
     CDS             4888..5118
                     /locus_tag="JAM15_17520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HAT6800043.1"
                     /translation="MSNKKKKYANILANECVACGSCIKACPRSAISVPCGISAKINRD
                     LCVGCGICEKICPASVIEIITILKEEEGKCHE"
     gene            5111..5692
                     /locus_tag="JAM15_17525"
     CDS             5111..5692
                     /locus_tag="JAM15_17525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HAT6800044.1"
                     /translation="MNNKKHWYDYLWIFSSIYLVLGFVNIIFAWIGLICFFVPLAISI
                     VKGNKAYCNKYCGRGQLFNLLGNKLKLSRNRDIPKFIRSKWFRYGFLTFFMVMFANML
                     FSTYLVFEGSRNFKEVVTLLWTIKMPWQWAYHGTLVSPWVVQFAFGFYSVMLTSTVLG
                     LITMILFKPRSWCVYCPMGTMTQMICKAKSKSV"
     gene            complement(6271..6948)
                     /locus_tag="JAM15_17530"
     CDS             complement(6271..6948)
                     /locus_tag="JAM15_17530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAT6800045.1"
                     /translation="MISQNEIDILTHSLPFWDKLTDLQKELLISSANTSHYKKGNPVH
                     CGDSDCIGILIIKSGTIRTYILSDEGREVTLFRLDDGDVCILSASCILKTITFDVYVD
                     AETDCDIIQINSSVFAKLSTENIHAELFSYKLATERFSDVMWAMQQILFMSFDKRLAS
                     FLIDEIAKNGSSTINMTHEQIAKYMGSAREVVSRMLKYFAREGIVSLSRGGIKVLDKD
                     KLRSLTL"
     gene            complement(7137..8501)
                     /locus_tag="JAM15_17535"
     CDS             complement(7137..8501)
                     /locus_tag="JAM15_17535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HAT6800046.1"
                     /translation="MKESNKKIELLGSAPISKALLSMGLPTMIGMMITALYNLVDAYF
                     VGGLGTSQMGAISVAFPLGQLVVGLGLLFGNGAASYIARLLGHGDNEKAGKVVSTSIY
                     SSIIVGTLVIIVIMIFLNPILKLLGATKSIMPYAISYASIYVVSSIFNIFNVTMTNIV
                     TSEGAAKTTMCAMLLGALLNMILDPIFIYTFGLGVRGASIATTISQIASTLVYVGYIL
                     SKKSIFSFRINECCFSKEIFSEILKIGIPTLIFQLLTSLAITLTNMEATKYGDSVIAG
                     MGAVTRITSLGSLIVFGFIKGFQPIAGYNFGSKNYDRLHIAIKTSILWTTIFCVVLGL
                     ILVLFPKSIISQFTSGDILLIENGSKALRANGFSFMLFGFYTVYSTLFLALGKAKEGG
                     FLGMCRQGVCFIPIILIIPVFYGLNGILYAQPIADLMAAIIAGFMSIRLHKELNLLKI
                     NGMH"
     gene            8629..9150
                     /locus_tag="JAM15_17540"
     CDS             8629..9150
                     /locus_tag="JAM15_17540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAT6800047.1"
                     /translation="MATIDLIVLGIVKQQPKSAYDIQKAVEYRNISRWVKISTPSIYK
                     KVIQLEQKGYIESKTVKNGKMPEKAVYSLTELGETHFLDLMFDTSSKPINILLDFNAV
                     IVNLNSLTPEKQKLCLNNIEENVQELKKTIEENISIKTEVPETAKAVLEQQLVLAQAL
                     ETWINSLKDNMGN"
BASE COUNT         3688 a          999 c         1588 g         3019 t
ORIGIN      
        1 tagtagaaat gggggaaata gagatgaata agggatttta caaattaaat tcagtggtat
       61 tgaactttga tattaagaat gatgttaaca agataagatt taatcattat ataatgagaa
      121 aagaaaacat acaaagactt caaggaactc tgccaaacgg acaattttat atgacagtga
      181 gaagagctgc tacagattta caactttcta tttctactat aagtaggctt gtaaaagagt
      241 ttttggattt agggataata agattagtgt ctaagggtgt aaaaggtaat cgttctgtat
      301 atagttacgt aagtatagag tttaatggaa gtttatttga tgatagcaaa tatatggaac
      361 ttgactgtgt atgtaatgat gaatttattg ataatagtgg catagagttt gattgtgata
      421 gcaaagataa ttcttttaat ggagatataa atgtagaaac tgtgcattgc attaatgagt
      481 atttctctga tgatgatgta gagcataatt ataacaattt ccataataaa gatactataa
      541 aggataaagc catttctaat attagcacta tcaaaaaata tattgatgaa tcttttgata
      601 caaataaatc agaaaattct aacttacaac aggagtcaat aaatttcaac tttaatgata
      661 catgcaatga aatagataaa agaacgaata atagtataga aaataatcaa aataaaaggc
      721 ctatgagatt gagtgacatc agtgttttaa gtgataaagg tatgacaaat aaaaagaatt
      781 actttaatca taatcatggt atacaaaaaa ggaataaatc tgcaacaaag aaaaaagaat
      841 ccttaaataa atttaataaa aaaaatatac agcaaagcat tataaatatg ctaaataaaa
      901 aatcaggtaa gaattttaaa atcgattctc caataagcat aaaacttatc aatgaaaggc
      961 taaaggaggg ctatgtctta gaagatttct ataaagttat tgaggtaaaa gtggctaagt
     1021 ggaaaaatac cataatggaa atgtatataa gaccagaaac cttgtttagc tataagtttg
     1081 aatcctatgt aaatgaaaac atatctatga aaagtcaaag taatgttcac ccatgtaaag
     1141 aaggcaatag taatgatagc agtaattata tacattctga ttatacaaca tatgatggca
     1201 gtgtgcgtga gagaaaaaaa tatgagaatg taagatactg gaatcctata tgtgaaattt
     1261 aattagttta agaatgtatt tatgataaat aagatattaa tagagaatag tgagctatag
     1321 caaatgatat atcaataatt ggtagtaagt tatattaagt aagatattac tatcaggtag
     1381 tgaattatat tgaacgatat atcaataatt ggtagtaaat tatattaagt aagatattac
     1441 tatcaggtag tgaattatat tgaacaatat ataaataatt ggtagtaagt tatatcaaat
     1501 aagatattac tatagagtaa tgaattatat tggacgatat atcaataatt ggtagtaaat
     1561 tatattaagt aagatattac tatcaggtag tgaattatat tgaacgatat attaataatt
     1621 ggcagtaaat tatattaaat aagatattac tatagagtaa tgaattatat tgaacgatat
     1681 attaataatt ggcagtaagt tatatcaaat aagatattac tatagagtaa tgaattatat
     1741 tgaacgatat attaataatt ggcagtaagt tatatcaaat aagatattac tatcaagtag
     1801 tgaattatag tgaacgatat attaataatt ggcagtaagt tatatcaaat aagatattac
     1861 tatagagtaa tgaattatat tgaacgatat atcaataatt ggtagtaagt tatatcaaat
     1921 aagatattac tatagagtaa tgaattatat tgaacaatat attaataatt tgtagtaaag
     1981 tatatcaaat aagatattgc tattatgtag taaattatat aaaacaatgt atcagaataa
     2041 atagtatatt aataatttgt agtatatcat gacgaataat acagtcataa caaatagtga
     2101 gtcataacaa ataatgtatt tataattgat aatgtattta aaaatcaaaa tataaaaact
     2161 tataaggaaa gagagattaa tttatatggg taaatcaaaa gatgttgaaa tagagaagtc
     2221 tattttaggc acaattcttt tagacaataa attaagctat aagctagatg aattaaatga
     2281 aaacatgttt atgaatgata tatgtcttga gatatttaaa attatgaaag aacttaaaaa
     2341 agaaaacata gtgattgatg tggccactgt gaaatcaaag atagatagaa aatctctagc
     2401 aataaaaacg agtgatgtga ctaatctaat tacttggggt cagaattttg gtcttgatgg
     2461 tcatattaaa attttaaaag aaaatttagc tagaagaagc ataaatcaaa actgccaaaa
     2521 ccttttacac agcctaaacc ttggagaaaa tatcgatact tgtatttaca aatttgaaag
     2581 taatataaag gagattttgg acaaggatac ttatgaaaat gatgatgtaa atagtatagc
     2641 agggaaggtg cttgattttt tagaaaacaa aaaagatatt ggatttaaat ttggtataaa
     2701 attacttgat actactatag gaggtctttt taaaggagag ctaaccacaa tagcagctaa
     2761 atcgggggtt gggaaaactg ctttggcact tcaaataatg ttaaattcat ttaagcaagg
     2821 taaaaaaact ttatttataa gtagagaaat gaccagtgag caagtattta tgagaaatat
     2881 atgcagagta actggtgtaa gtacaaggaa tatgaaatct aaagaaatag atgaaaatga
     2941 ttggaaactt attgtaaatg ctataggtga tttaagcgaa aataacttaa tttatattaa
     3001 tgataagata gatacaatta gtgcaattag aaagaggata aggcaggtaa agccagattt
     3061 attaatagtg gattatgtgc aactccttac atctcagaaa agcatggata agagagaaag
     3121 ggaggtagct actttttcga gagaacttaa aaatatgact ttagatttta atatacctgt
     3181 aattcaatta agtcagttaa atgatgaaat gaaagattca agaccttatg gagatagacc
     3241 tatgagggat agcaaagcca tctaccacga tagcaacaat gtggtttata tacatcaatt
     3301 aaaagggagt gattatgaag aagcagtgag agatattgga gaaagtgagg aggcagttag
     3361 agcatcagaa tacaggggaa ttaagatggt tgatttaata gttgcgaagt gtagagatgg
     3421 acagactagg cataagcatt tttgttactt tggggataag ttacattttc aagaactaaa
     3481 ttattaggtc aataaagtag taataacaag cttattaaaa gtcgggaaat agcaaataga
     3541 ttataaaata tgaggtgaaa atatgttgga attaacgaaa attatagaat tacttgaaga
     3601 acacaagata gaagtaagta ttccaaagga gttacataag tatagtttat tggaatacct
     3661 tgaattgtgt caacaaagtg ggggaacata tttttatatt aaaacactgg aaggggcatt
     3721 aaaagaggct agaaatgagc ttatgattaa attgtttaat gggaaaaatt atatggaatt
     3781 agcgaggatg tttgaaatga gtgttattaa tgtcaggcat attgttagaa aaaaatagat
     3841 atttttggag aatacaagtg tgatatactt ctgaaataga agttattata gttgaaataa
     3901 aattgtggct aatttgtgta taagtttaag attatagagg agtataagtg tgattaacag
     3961 catgattttg tgaataaaat tgatgatata tatgagttaa atgtgtgatt aataaggtaa
     4021 ggttgtgtat aagattatga gtatttaaaa ggaggggcta taattaatag tgtagagttg
     4081 tatgtttgct taagattata taataattta atagattaaa ctatacgaat aaggtaaaat
     4141 cgtgtgttta gttaaagctt attataaaat cttgacatgc gattaatgat gcaatatgtg
     4201 aataaagtta agattataat aaatttaacc tgtggctaat agaataaaat tgtgaataaa
     4261 gttaagatta taataggttt aatctgtgac taatagagta agagtgtaaa tagagataaa
     4321 cttcaatatg ggtttaacct gtgattaata gagtaagagt gtaaatagag ataaacttca
     4381 atatgggttt aatctgtgat taatagagta aggtgtaact aaagataaac ttcaatatga
     4441 gcttaaccta tgattaatag agtaagaatg taaatagaga taaacttcaa tatgggttta
     4501 acttgtggtt aatagagtaa ggtgtaacta aagataaact tcaatatgag cttaacttgt
     4561 ggctaataga ataagattgt gaataaagtt atagttttag atgggtatta acctgttact
     4621 aatagaatat gattaggtgt aaaattatag agctgtataa gaaaatatta tagatatatt
     4681 aaatattaga taataaatat ttatatagat acacaaaaga aaaggcgata tgaagctaaa
     4741 cttaatgact tcatatcgtt ttttatttga aactcctttg tatttagagt gtgattttta
     4801 atattgaggt tttatgtgat taagtcacag ataaaaagta agtatcttga tataattctt
     4861 atagattaat aatataggga ggttattatg tctaataaaa aaaagaagta tgcaaatatt
     4921 ttagcaaatg agtgcgttgc ttgtggtagc tgtataaaag catgtccaag aagtgctatc
     4981 tcagttccat gtggcattag tgcaaaaatt aatagagatt tatgtgttgg atgtgggatt
     5041 tgtgaaaaga tatgtccagc atctgtaatt gagattataa caatattaaa agaggaagaa
     5101 ggtaagtgtc atgaataata aaaaacattg gtatgactat ttatggattt tttcttcaat
     5161 atatttggta ttgggatttg taaatattat tttcgcttgg attgggctaa tttgtttctt
     5221 tgttccacta gctatttcta ttgttaaggg aaataaagct tactgtaata agtattgtgg
     5281 aagagggcaa ctgtttaatt tgcttggaaa taaattgaag ctgtcaagaa atagagatat
     5341 tcctaaattt attagaagta agtggtttag atatgggttt ttgacatttt ttatggtaat
     5401 gtttgccaat atgctttttt caacttattt agtgtttgaa ggaagtagaa attttaaaga
     5461 agtagtgact ttgttgtgga ctataaaaat gccttggcaa tgggcgtatc atggaacttt
     5521 agtttcacct tgggtggtac agtttgcatt tggtttttat agtgttatgc ttacatcaac
     5581 tgttcttggt ttgattacta tgatattgtt taaacctcgt tcatggtgtg tttattgccc
     5641 tatgggtact atgactcaga tgatatgtaa ggcaaagagt aagtctgtat aggaaggctt
     5701 tatgtgatat ttacagtttt gttcaagtag agatgagtag taggtttgaa tatatatgac
     5761 aaatatatga gtataggggc atagatttag tttgtgtaag gtaaactgat ttatgcttct
     5821 tttttatgtc ttagattatt ggctaagtgg aaacaatgaa tttagatatt aataattatt
     5881 cagttatttg aagaaaatat aataataatt aacattatat taatggatat tcattacata
     5941 taagccagtt aatagcaaga tttatttaat atgaaatagg tcaagtattt aaactaaata
     6001 aggtcatgac aattaatata agtatagata taaaaagatt agaagttata acttataaaa
     6061 ggtattctat ataaatagta tgtggaaaat agtcaaatta acttattaga aacaaaaaat
     6121 atacataaaa aataaatgta aatatcaaat aagatactat ataaaaatag atataagtat
     6181 cttttttatt attgaaatta tgaaaatata tttgatttca cacaaaaaag agtgcctcat
     6241 gaactaaaaa gttcattttg agacacactt ttacagtgtc aaagaacgaa gtttatcctt
     6301 atccaatact tttataccac cacgagataa agacacaata ccttctctag caaaatattt
     6361 caacattctc gatacaactt ctctggcact acccatatac ttagcaattt gctcatgagt
     6421 catatttata gtgctactgc catttttagc tatctcatca attaaaaaag atgccaaacg
     6481 cttatcaaaa ctcataaaaa gaatttgttg catagcccac ataacatcag aaaaacgttc
     6541 ggtagctaat ttatatgaaa ataactctgc atgaatattt tctgtagata attttgcaaa
     6601 aacagaggaa ttaatctgta taatatcgca gtccgtttca gcatctacat agacatcaaa
     6661 agttattgtt tttagaatac aggaagctga taaaatacat acatctccat catcaagtcg
     6721 gaacagtgta acctctcgac cttcatctga aagtatgtat gtacgtattg ttccagactt
     6781 tataatcaaa ataccaatac agtcactatc accacaatgt actggattcc cttttttgta
     6841 atgcgaggta tttgctgaag aaattaataa ttctttttgt aagtcagtaa gtttatccca
     6901 aaaaggcaag ctatgtgtaa gtatatcaat ttcattttgt gaaatcatac aatatctcct
     6961 ttcttaaatt gttataatcc catgatacaa gtgaatagat aaattgacaa gtagtttgtt
     7021 aagaggatta tttagtcaga tagtaatagt atgatttatg tagaaaaaat atgataatat
     7081 agattcttgc tattaatgag aaagtgatat gttttgatga tagtaggttt gtataactaa
     7141 tgcataccgt ttatttttaa aagattaagt tccttatgta accttataga cataaaacca
     7201 gcaattatag cagccatcaa atcagctatt ggttgtgcat ataagatacc atttaaccca
     7261 tagaatacag gaataatcaa aattataggg ataaaacaga cgccttgtct acacatacct
     7321 aaaaatccac cttcctttgc ttttcctagt gctaggaata atgtagaata cactgtatag
     7381 aatccaaata gcataaatga aaacccattt gccctaagag ctttactacc attttctatt
     7441 aatagaatgt caccacttgt aaattgtgaa attatagatt ttgggaaaag caccaatata
     7501 agaccaagca ctacacaaaa tattgtagtc cataatatgg aagtttttat tgctatatgt
     7561 aatctatcgt agttcttcga accaaaatta taaccagcaa ttggttggaa accttttata
     7621 aaaccaaata caataagact acctaaagat gttattcgtg ttacagcacc cattccagct
     7681 atcacagaat caccatactt tgtagcctcc atattagtta atgtaatggc aagactagtc
     7741 agtaattgaa atattaaggt aggtatgcca atttttagga tttctgaaaa aatttctttt
     7801 gaaaaacagc attcgttaat tctaaaacta aatatacttt tcttgcttaa aatatatcct
     7861 acataaacaa gtgttgaagc aatctgtgag atagttgttg caatagaagc accccttacc
     7921 cccagaccaa aagtataaat gaatatcggg tctaaaatca tattaagcaa agcacctaat
     7981 aacatagcac acatagttgt tttagcagct ccttcacttg tgacaatatt agtcatagtg
     8041 acattgaata tattaaaaat agatgacacg acataaatgc tagcataaga tattgcataa
     8101 ggcataatac tttttgtagc tcctaacaat tttaaaattg gattgagaaa aatcataatc
     8161 acaataataa ctaatgtacc cactataata ctactgtaaa tagatgtact taccactttt
     8221 cctgcttttt cattatcacc atggcctaaa agtctggcaa tatatgaagc agctccattt
     8281 ccaaacaata atcctaatcc cacaacaagc tgacctaatg gaaatgcaac ggatatagct
     8341 cccatttgac ttgttccaag tccacccaca aagtatgcat caaccaaatt gtataatgca
     8401 gttatcatca tacctatcat ggtaggtaat cccatagata acaatgcttt tgagattggg
     8461 gcagacccta ataattcaat ttttttgtta ctttctttca tacttaacac tcctcttcta
     8521 ttgacattaa gtctaaatta taatactata aattatagta agtatggaaa atagtactat
     8581 aatttatagt atttgtcaat agtaagaaaa ctaaaggaga tgatttttat ggctacaata
     8641 gatttaattg tattgggaat agtaaagcaa caacccaaga gtgcttatga tattcaaaag
     8701 gcagtggaat acaggaatat atcacgttgg gttaaaataa gtacaccatc aatttataaa
     8761 aaagtaattc aattagaaca aaagggatat attgaaagta aaactgtgaa gaatggaaaa
     8821 atgccagaaa aagcagttta ttcattaact gaattaggtg agacacattt tttagattta
     8881 atgtttgata catctagcaa accaataaat attcttttag attttaatgc tgttatagta
     8941 aatttaaata gccttacacc agaaaaacag aaattatgtc tcaataatat tgaagagaat
     9001 gttcaagagt taaagaaaac tattgaggaa aatataagta taaagacaga agtaccagag
     9061 acagcaaaag cagtgttgga gcaacagttg gtgctagcac aagcattgga aacctggata
     9121 aattctttaa aagataatat ggggaattag aattagagaa gctaacttaa taatcattaa
     9181 acaaaaacca gcatatttaa taatgagata ttagaaaaaa tgaaacaaat gatataaact
     9241 gaaaagtata tttaaaataa agctcactta attgagggag aatgttaaac tttt
//
LOCUS       DACTZW010000124         8764 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.125, whole genome shotgun sequence.
ACCESSION   DACTZW010000124 DACTZW010000000
VERSION     DACTZW010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8764
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.125"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            164..1225
                     /locus_tag="JAM15_17545"
     CDS             164..1225
                     /locus_tag="JAM15_17545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium/sodium antiporter"
                     /protein_id="HAT6800048.1"
                     /translation="MEKRKSIHLHKLNIYLIGGGDRLFITVVLFLVGFLLITKGADIF
                     INCTVEIGRKTNISEIILGATIVSFATTLPEFTVSLLASIDGHTTMSLGNAVGSIICN
                     TGLALGLVVFISPFNVDKKMFFSKSLLLIVSVIVLILLSLDGVITRGDSLLLIIILIF
                     YMVNNYRSVVGKSDTKNRNIKNNTIKDISTKKGKNYRGFSVLEIVKILLLFATGLIMM
                     IIGSQILIESGVIIASFLNIPQGIVSLTIIALGTSLPEIVSSITAIRKNHHEISVGNI
                     LGANILNIVSVIAVSAIPNNIPILSQNRQLDIPFMILLLLIVIIPTLKSNRLSRIQGI
                     LMLFTYFLYISILYFMYII"
     gene            1316..2929
                     /locus_tag="JAM15_17550"
     CDS             1316..2929
                     /locus_tag="JAM15_17550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002845095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAT6800049.1"
                     /translation="MNITKFEDLPISEGIKKAIAEMGFEEPSPIQAQSIPAILSGKDV
                     IGQAQTGTGKTAAFSIPILETIDPNNRSLQAVVLCPTRELAIQVSTEIRKLAKYSHGI
                     KTLPIYGGQPIDRQIKSLKSGVQVVIGTPGRTIDHINRKTLKMDNVKMIILDEADEML
                     DMGFREDIEMILSKIPEERQTTFFSATMPRGILELTKRYQKDPEHIKVVRKELTVSNT
                     KQYYIETRSSNKLEVLCRLVDVYDPKLSVVFCNTKRKADELVGDLQARGYFADALHGD
                     LKQTQRDIVMDKFRNGTIDILVATDVAARGIDVDDVECVFNYDLPQDEEYYVHRIGRT
                     GRAGREGMSFTFVFGKEMRKMKDIERYTKSKLIKHNIPTITDVEEKKVGTFFAQVKQT
                     IEEGHLTKQLQWLEGFCNDEDYAMVDIAAALVKLSLGEEMKEEIIEEKPRRERGDRKG
                     GTGAKDGMIRLFINIGRNQRVQAKDIVGAIAGEVGIPGKVVGTIDIYDKYTFVEIPKK
                     DAKTVIEKMKDIKIKGNKINIEKANKKKK"
     gene            3204..5189
                     /locus_tag="JAM15_17555"
     CDS             3204..5189
                     /locus_tag="JAM15_17555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HAT6800050.1"
                     /translation="MSMTYMDPRVFLILEMVLEEDTNTLEQFSNVLGVSTRTIRNYIN
                     QINRELKGGIAKIVKNEKGTYSIRIEDESKLIEIVNFNRGKLSNFINLNSPDERINYV
                     LDILTMTNNPITIDDLAEEICIGRTTLIKDLKKADRILAEYDLELKRKPNIGMILVGE
                     EMDIRLLILDRLYENYIDVLENVNQINLVKDYDIECLRDELKKLFKKEELYITEQVLR
                     DVERYIIMSVLRNLNGYKFEKIDKRFEVIRCSDEYTLGLKLKALLEKIFNIVLNEKET
                     IFLTMPLIGRKAPSTKLALSSIKINDSVKEVVDEVTSFLLETSGIDFKEDKKLIENLE
                     YHLYFALNRMRFNIRVKNPLLQEIKERYTFPYSVAKIAAMIIEEKFDLKICDHEIGYI
                     ALHFGSYFEKNSRKVLNVNRVAVVCGTGLGTAQLIRIKIGKILGESVEVNTFSDIEAK
                     ANLDLLKYYDLVFTTVDFKTDLDVPIFRVNALFNEESIKKEIENAILLKNSINLKSIK
                     KIEKNIPFIGKLIEEDKFFILNKSTFMENLEDMLEKLVHKGIIDIEFKKKVLKREKKS
                     STALDNYIALPHSVNTNGENLYLSFGILEKPVVWDTKEIRIIILMIIPDKNVDSTDLI
                     IKSYEEVLEVGRDKKMIEELAKVKSFDEFYKIITKRR"
     gene            5194..5628
                     /locus_tag="JAM15_17560"
     CDS             5194..5628
                     /locus_tag="JAM15_17560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAT6800051.1"
                     /translation="MDPVIFIIASLITVYLLNIFLGYLQLKDFNKNYIELKRKGRVAI
                     GRKKGRISSGTIVLILINDDGVIVETRKMQGVTVLARVKSFEGLVGKSLEYIEKSDLT
                     VYNKLLKKAILDAVKQYITFEKNKCEDTNNLSTDEECRMEVV"
     gene            5657..6217
                     /gene="srlA"
                     /locus_tag="JAM15_17565"
     CDS             5657..6217
                     /gene="srlA"
                     /locus_tag="JAM15_17565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012423036.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HAT6800052.1"
                     /translation="MTQFFQVLASGADSFMNLFRAGGQQFVGFVTDIVPLLVALLVTM
                     NAIINFIGTDRVERLAKKCSANIFTRYLILPVLGTFVFANPMTLSLGRFLPEKFKPSY
                     FAAASFSCHTMNGLFPHINPGELFIYLGIANGITTLGFSTADLAVRYLLVGIVANFIK
                     GVVTDYTTKFVEKQQGIALNSDIKIG"
     gene            6281..6649
                     /locus_tag="JAM15_17570"
     CDS             6281..6649
                     /locus_tag="JAM15_17570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sorbose transporter subunit IIB"
                     /protein_id="HAT6800053.1"
                     /translation="MAFNKVKIVKGSGGWGGPLIIEPTEKKNKVVYVTGGAKPETAVK
                     IAELTGCELIDGFSQGVKDDEIACVIINCGGTLRCGIYPQKKIPTINIMKTGKSGPLA
                     MFIKEDIYVSGVKPTNVEQL"
     gene            6674..7240
                     /locus_tag="JAM15_17575"
     CDS             6674..7240
                     /locus_tag="JAM15_17575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HAT6800054.1"
                     /translation="MAYDTKKKISEQSQGIVAKIGIALGNVTSTLFQAGRDTIDTLIH
                     TILPFMAFVAVLIGIINQSGIGNWVANLLTPLIGNVGGLVVLSIICSFPLLSPFLGPG
                     AVIAQIVGVLVGTEIGKGNIPPSLALPALFAINSQAACDFIPVGLGLAEAEPDTVQVG
                     VPSVLYSRFLTGAPTVLLAWLASFGLYK"
     gene            7281..7646
                     /locus_tag="JAM15_17580"
     CDS             7281..7646
                     /locus_tag="JAM15_17580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HAT6800055.1"
                     /translation="MELIYSTQINKIGDNANEFLQHNMFVTFKDNAPQELENYCYIHS
                     ENNLVKEILTNDVLSINNIDYKITSVGELVNQNLSELGHITFKFTGEKDGAIGGTLYL
                     EEKEIAPIGVGTILKIIRK"
     gene            7747..8520
                     /gene="srlD"
                     /locus_tag="JAM15_17585"
     CDS             7747..8520
                     /gene="srlD"
                     /locus_tag="JAM15_17585"
                     /EC_number="1.1.1.140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007930881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sorbitol-6-phosphate dehydrogenase"
                     /protein_id="HAT6800056.1"
                     /translation="MRKVALVVGGGRSLGEYLSKHLAKVGYDVAIADLNEDNAKKVAE
                     EIETEFGCKSVGYGCNAIDERQVISTVKAIENDFDRIDLLVYNAGVAVSKKITDFGYK
                     DFKFIVDVNLNGYFLFAREVSKVMIAKGIEGRIIQINSKSGRVGSKHNSGYSAGKFAG
                     VGLTQSLALDLAEHKITVNALMLGNLLDSDMFESLIPQYAVKLGIPESEVKQVYIDKV
                     PLKRGCRFIDVANMLTFYASKEAEYCTGQSINITGGQVM"
BASE COUNT         3503 a          886 c         1622 g         2753 t
ORIGIN      
        1 tgtatacata aaaaataaaa aattgtcgct ttaaagtata aaacagatta tatgttaata
       61 atgtggtgaa attataccca tatataaata aaataaaaca aataaatagc taattaagga
      121 gaaaatattt tttatttttt gtttaggata aataaatttt attatggaaa aaagaaaaag
      181 catacatctt cacaaattga atatttattt aataggggga ggtgatagat tgtttatcac
      241 agtggtatta tttttagtag gtttcctatt aattactaaa ggcgcagata tctttataaa
      301 ttgcactgta gagataggta gaaaaacgaa tatatcagaa attatacttg gagctactat
      361 agttagtttt gcaacaacat tacctgaatt tacagtgtct ctacttgctt ctattgatgg
      421 tcatactact atgagtttag gaaatgcagt tggttctata atatgtaata caggattagc
      481 attagggttg gttgttttta taagtccatt taatgtagat aaaaaaatgt ttttttctaa
      541 gtctttacta ttaatagtat ccgttatagt tttaatttta ttgagtttag atggagttat
      601 aacaagaggt gattcattat tacttataat aatattaatc ttttatatgg ttaataatta
      661 tagaagtgtc gttggaaaat ctgatactaa aaatagaaat attaaaaata acactattaa
      721 agacatatct actaaaaaag ggaaaaatta tagaggtttt tccgtattag aaattgtaaa
      781 aatactatta ctttttgcta caggattgat aatgatgata ataggttcac aaatccttat
      841 agagagtgga gtaataatag ctagtttttt aaatatacct cagggtatag taagtttaac
      901 tataatagca cttggaactt ctctgccaga gatagtttcg tcgattactg ctataagaaa
      961 aaatcatcat gaaatatcag taggaaatat tttgggtgca aacatattga atatagtatc
     1021 agtaatagct gtatcagcaa taccaaataa cataccaata ctatctcaaa atagacaatt
     1081 ggatatacca ttcatgatat tattattatt aatagtaata ataccaacac ttaaatctaa
     1141 tagacttagt agaatacaag gtatattgat gttattcaca tattttctgt acatatcaat
     1201 tttgtatttc atgtatatta tttaactata ctgtttaaaa tattaattgc agaatatcct
     1261 aaaaaagtat ataatggata ggttaagatt aattgataac ggagaggaat aatatatgaa
     1321 tataacaaag tttgaagatt taccaataag tgagggaata aaaaaagcta tagctgaaat
     1381 ggggtttgaa gaaccatctc ctatacaagc acagtctata cctgcgattt tgtcaggtaa
     1441 agacgttata ggacaagctc aaactggtac gggaaaaaca gctgctttta gtatccctat
     1501 actagaaaca atagacccaa ataatagaag tttacaagct gtagtgcttt gtccaacaag
     1561 agaactggca atacaagtat caacagaaat aagaaagtta gctaagtatt cgcacggaat
     1621 aaagacatta cctatatatg gtggccagcc aatagataga caaataaaat ctctaaagag
     1681 tggtgtgcaa gttgtaatag gtacaccagg acgtacaata gaccatatca atcgtaaaac
     1741 attaaagatg gataatgtaa aaatgattat attagatgaa gcagatgaaa tgctagatat
     1801 gggatttaga gaagatatag aaatgatttt aagtaagatt ccagaagaaa gacaaacaac
     1861 tttcttttca gctactatgc caagaggaat tttggaatta actaagagat atcaaaaaga
     1921 cccagagcat ataaaagttg ttagaaaaga acttacagtt tcaaatacaa agcaatacta
     1981 tatagaaact aggtcatcaa ataaattaga agtattatgt agattagtag atgtatatga
     2041 ccctaaacta tctgttgttt tctgtaatac taagagaaaa gcagatgaat tggtaggaga
     2101 tttacaagca agaggatatt ttgcagatgc attacatggt gacttgaaac agactcaaag
     2161 agatatagta atggataagt ttagaaatgg tacaatagat atacttgttg ctactgatgt
     2221 tgcagctaga ggtatagatg ttgatgatgt tgaatgtgta ttcaactatg acttaccaca
     2281 agatgaagag tattacgttc atagaattgg tagaactggt cgtgctggta gagaaggtat
     2341 gtcatttact tttgtatttg gaaaagaaat gagaaagatg aaagatatag aaagatatac
     2401 taaatctaaa ctaataaagc ataatatacc aacaataact gatgttgaag agaaaaaagt
     2461 aggtactttc tttgcacaag ttaaacaaac tatagaagaa ggtcacttaa ctaaacaatt
     2521 acaatggtta gaaggtttct gtaatgatga agattatgca atggttgata tagctgctgc
     2581 acttgtaaaa ctatctctag gtgaagaaat gaaagaagaa ataatagaag aaaaacctag
     2641 aagagagcgt ggagatagaa aaggtggtac tggagctaaa gatggtatga ttagattatt
     2701 tatcaatatt ggtagaaatc aaagagtaca agcaaaagat atagttggtg ctatagctgg
     2761 agaagttgga ataccaggta aagtagtagg tactatagat atatatgata agtatacttt
     2821 tgttgaaata cctaaaaaag atgcaaaaac agtaattgaa aagatgaaag atattaagat
     2881 aaaaggtaat aagattaata tagaaaaagc aaataagaag aaaaaataac gtatagtata
     2941 caaaactata attagaaaat atataaaata atatattgga tatttaaaaa gcctgatgtg
     3001 ttttcaaaac agatagtaga taatctgtaa gagttaacag cataaggctt ttcttgtttt
     3061 atatgatatt atgattttcc agatcgttgt gaaaaatgta tattagttcc tttttttcaa
     3121 atctgatttg aaaaagagaa tattaattat ctatatagtt tagattataa taaaaaatgt
     3181 aagataacaa aggggagaaa aagatgtcaa tgacttatat ggaccctagg gtttttttga
     3241 ttttagaaat ggtgttagaa gaagacacaa atactctaga acaattttca aatgttttgg
     3301 gtgttagtac taggactatc agaaactata taaaccagat taatcgagaa ttaaaaggtg
     3361 gtattgctaa aatagttaaa aatgaaaaag gtacatatag tataagaatt gaggatgaaa
     3421 gtaaattaat tgagattgta aattttaata gaggaaagct atcaaatttt ataaatttaa
     3481 attcacctga tgaaagaata aattatgttc ttgatatttt aactatgacc aacaatccaa
     3541 ttaccataga tgatttggct gaagagatat gtataggaag aacaacatta ataaaggatt
     3601 taaaaaaagc agacagaatt ttagctgaat atgatttaga attaaaaagg aagccaaata
     3661 taggtatgat tttagttggt gaagaaatgg atataagatt attaatcctt gatagattgt
     3721 atgaaaatta tattgatgtc ttggaaaacg ttaatcagat aaatttagtt aaagattatg
     3781 atattgaatg tcttagagat gaattaaaaa agttgtttaa aaaagaagaa ctctacataa
     3841 cagaacaggt cttgagagat gttgaaagat atataatcat gtctgtctta agaaatctaa
     3901 atgggtacaa atttgaaaag atagataaga gatttgaagt gataagatgt tcagatgaat
     3961 atactttagg attaaagctc aaagctttat tggaaaagat atttaatata gttttaaatg
     4021 aaaaagaaac catatttttg acaatgccat taataggtag aaaagctcct agtacaaaat
     4081 tagcacttag cagtataaag ataaatgata gcgtaaagga agttgtagat gaagtaacta
     4141 gttttttatt agagacctca gggattgatt ttaaagaaga taaaaagctt atagaaaatt
     4201 tggaatatca cttgtatttt gcacttaata gaatgagatt caacataagg gtaaaaaatc
     4261 ctcttttaca agaaataaag gaaagatata catttccata tagtgttgca aagatagctg
     4321 caatgataat tgaggaaaag tttgacttga aaatatgtga ccacgaaata ggatatatag
     4381 cattacattt tggaagttat tttgaaaaaa attcaagaaa agttctaaat gtaaataggg
     4441 tagctgttgt ttgtggaaca ggtcttggga ctgcacaact tattagaata aagataggaa
     4501 aaatacttgg agaaagtgta gaagtaaata ctttttctga tatagaagct aaagctaatt
     4561 tagatttatt aaagtattat gatttagtat ttacaacagt agatttcaaa acagacttag
     4621 atgttccaat ttttagagta aatgcgttat ttaatgaaga aagtataaag aaagagatag
     4681 aaaatgcaat acttttgaaa aatagtataa atcttaagtc tataaaaaag attgaaaaaa
     4741 atatcccttt tataggtaaa ttaattgaag aggataagtt ctttatattg aataagagta
     4801 cgtttatgga aaatttagaa gatatgttag aaaaattagt tcataaagga attattgata
     4861 tagagttcaa aaaaaaggta ttaaaaagag aaaagaaatc ttcaacagca ttagataatt
     4921 atatagcatt gcctcactca gttaatacta atggggaaaa tctttatctg tcatttggaa
     4981 tattagaaaa accagtggtt tgggatacaa aggaaattag aataataata ttgatgataa
     5041 ttccagataa gaatgtagat agtacagacc tgataataaa aagttatgaa gaagtacttg
     5101 aagtagggag agataaaaaa atgatagaag aacttgctaa agtaaaatca tttgatgaat
     5161 tttataaaat aattaccaag aggaggtaat aatatggacc cagtaatttt tattatagca
     5221 tcacttatta cagtgtattt attaaatatt tttcttggat acttacagct taaagatttt
     5281 aataaaaatt atattgaact aaaaagaaaa ggaagagtgg caataggcag aaaaaaagga
     5341 agaatttcat caggtacaat tgtgttgata cttataaatg atgatggtgt gattgtcgaa
     5401 actagaaaaa tgcaaggtgt tacagtattg gcaagagtaa agtcatttga aggtttggta
     5461 ggaaagagct tagagtacat agaaaaatca gatttaactg tttacaataa actacttaaa
     5521 aaagcaatac tagatgcagt caaacagtac ataacatttg agaaaaataa atgtgaagat
     5581 acaaataatc tgagtactga tgaagagtgt aggatggaag tagtttaaaa aaatatattt
     5641 ataaggagga gttaatatga cgcaattttt tcaagtatta gcaagtggtg cagatagttt
     5701 tatgaattta tttagggcag gtgggcaaca atttgtaggt tttgtaacag atatagtacc
     5761 acttttagta gcattattag ttacaatgaa tgcaattatc aactttattg gtacagatag
     5821 agtcgagaga cttgcaaaaa aatgttctgc aaatatattt actagatatt tgatattacc
     5881 agtccttggt acatttgtat ttgcaaaccc aatgacacta tcactaggaa gattcttgcc
     5941 agaaaagttt aaacctagtt actttgcagc agcaagcttt tcatgccata caatgaatgg
     6001 attattccca catatcaatc caggtgaact atttatatat ctaggaattg caaatggtat
     6061 aacaactttg ggattctcaa cagcagattt agcagttaga tatttgttag tgggtatagt
     6121 tgcaaacttt attaaaggtg tagttactga ctatacaaca aaatttgtag agaaacaaca
     6181 aggaatagca ttaaattcag atataaagat tggataatta ctttaaggta taaataaatt
     6241 tttcaaataa aaagatagtg tatagaggag gataaattat atggcattta acaaagttaa
     6301 aatagtaaaa ggttctggag gatggggtgg accattgata atagaaccaa cagaaaagaa
     6361 gaataaggta gtatatgtga ctgggggagc aaagccagaa actgcagtaa aaatagctga
     6421 acttacagga tgtgagttaa tagatggatt ttcacagggt gttaaagatg atgaaatcgc
     6481 atgtgtaata ataaattgtg gtggaacatt gagatgtggt atatatcctc aaaagaaaat
     6541 accgactata aatataatga aaacaggaaa aagtggacca ttagcaatgt ttataaaaga
     6601 agatatatat gtttcagggg taaaaccaac aaatgtagag cagttataat tgaggtagta
     6661 ggagggaaga aatatggctt atgatactaa aaagaagata agtgagcaga gtcaaggaat
     6721 tgttgcaaaa ataggtatag cactaggaaa tgtgacaagt actctttttc aagctggtag
     6781 ggatactata gatacattaa tacatactat actgcctttt atggctttcg ttgcagtcct
     6841 aataggtata ataaatcaat caggtatagg aaattgggta gccaatttac ttactccatt
     6901 aatcggaaat gttggaggtt tagttgtctt atcaataata tgttcatttc cgttgttgtc
     6961 tccgtttctt ggaccaggag ctgttatagc tcagatagtg ggggtattgg ttggtacaga
     7021 aataggaaaa ggaaatattc caccaagttt agcattacca gcattgtttg caataaactc
     7081 acaagcagct tgtgacttta taccagtagg tcttggtctt gcagaagctg aacctgatac
     7141 agttcaagta ggagttccgt cagttttata ttctagattt ttaacaggtg caccaactgt
     7201 tctattagca tggttagcaa gctttgggtt atataaatag aagaatactt tataaataat
     7261 tagagagagg ttcagttgat atggaattaa tatacagtac tcaaataaat aaaataggag
     7321 ataatgcaaa tgaattttta caacataata tgtttgtaac tttcaaagat aatgctcctc
     7381 aagagttaga aaattactgt tatatacatt ctgaaaataa tttagtaaaa gaaatactta
     7441 cgaatgatgt gctatcaata aataatattg attacaaaat tacttctgtt ggtgagttag
     7501 taaaccaaaa tctttcagaa ttaggtcata taacatttaa gtttacaggt gaaaaagatg
     7561 gagcaattgg aggaacctta tatcttgaag aaaaagaaat agcacctatt ggcgtaggta
     7621 ctatactaaa aataattaga aaataaaatt taaaacgaat ctaatcatat tataagtaaa
     7681 ttatagataa aagtcaattt aactaatcaa gttaactttt aatgtgataa aaaaggggaa
     7741 atgaaaatga gaaaagtggc tttagttgtt ggaggaggaa gaagtttagg tgaatattta
     7801 tctaaacatt tagctaaagt aggttatgat gttgctattg cagatttaaa tgaagacaac
     7861 gcaaaaaaag tagctgaaga aatagaaact gaatttggtt gtaaatctgt aggatatggt
     7921 tgtaatgcca tagatgaaag acaggttata agtactgtta aagctattga aaatgatttt
     7981 gatagaatag atttattagt gtacaatgca ggagtggctg taagtaaaaa aataactgat
     8041 tttggataca aagattttaa atttattgta gacgtaaatt taaatgggta ctttctattt
     8101 gcaagagaag tatctaaagt catgatagca aaaggtattg agggtagaat catacagata
     8161 aattcaaaat caggtagagt gggaagcaag cataattcag gatattcagc aggtaaattt
     8221 gctggagtag gacttactca aagtttagcg ctagatttgg cagaacataa gataactgta
     8281 aatgcactga tgctcggtaa tttacttgat tctgatatgt ttgaaagttt aattcctcaa
     8341 tatgcagtaa aattgggaat acctgaatca gaagtcaagc aagtttatat agataaagta
     8401 cctttaaaaa gagggtgtag atttatagat gttgcaaata tgcttacatt ttatgcttca
     8461 aaggaagctg aatactgtac tggtcaatct ataaatatta ctggtggaca agttatgtaa
     8521 ggtttttatg gagtgtctca agatgaactc tttagttcat gaggcacttt ttttgtataa
     8581 aattaaatat attttcatca tttaaacaat gaaaaagagg tttatcttta ttttgagata
     8641 gcctcatttt tgtaattaag aaacatagtg tttaagtaaa catataagat tgttagtttt
     8701 ttaaaagaga attttttaat aatattatat ttatgaagta tttttaaact taatttgatt
     8761 aaaa
//
LOCUS       DACTZW010000125         8684 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.126, whole genome shotgun sequence.
ACCESSION   DACTZW010000125 DACTZW010000000
VERSION     DACTZW010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8684)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8684)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8684
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.126"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            196..546
                     /locus_tag="JAM15_17590"
     CDS             196..546
                     /locus_tag="JAM15_17590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002842710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAT6800057.1"
                     /translation="MSAKVTNQYGNIEIDNQVIAQVVYRAAMESYGLVGLAYKSKGIV
                     ELLKGENATKGVRVEEVEEDAIAIELYVIIQYGTNISTVANNIIDRVKYVVEKMTGVR
                     VTRIDINVQGIRVK"
     gene            565..2208
                     /locus_tag="JAM15_17595"
     CDS             565..2208
                     /locus_tag="JAM15_17595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HAT6800058.1"
                     /translation="MIQYIDGKRLREMFISGANNLQNNKELVDKLNVFPVPDGDTGTN
                     MSLTISYALKELAKVENDNISDIGKALSKGSLMGARGNSGVILSQIIRGIAKSIEGKS
                     KLSTEDLAKAFKNGSDTAYKAVIKPIEGTILTVVRESGEFAIKTAKKEKDVVKFLSML
                     VKESNSSLERTPDLLKNLKEAGVVDSGGKGLVLIYEGMLASIKGDNIETKNVDLDTNI
                     STSMDFAKSTTSTDDIKYCYCTEFILESSKVEDTKIRDIMMAYGDSLAVVGDDGVIKV
                     HVHTNDPGNVLQEALKYGQLLTIKIENMKLQHENTLLDVEEKKENDSEPLEEEKEFGF
                     IATSMGEGLANIFKDFGVDHIIEGGQTMNPSTEDFMNAIKHINAKNIFIFPNNSNIIM
                     AANQAKELSDKNIIVIPTKNTPQGFAALVTFNGELSEDENKEAMMNALNSVKSGQVTF
                     AVRDTVMNEIDVKEGNIIGIAEGNLLSAGDYVDEVTSNLIEKLVDEDTAIITLFFGED
                     VTESQANELRTSLEEKFEDVDVELYYGGQPLYYYLISVE"
     gene            2289..4346
                     /gene="recG"
                     /locus_tag="JAM15_17600"
     CDS             2289..4346
                     /gene="recG"
                     /locus_tag="JAM15_17600"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HAT6800059.1"
                     /translation="MDLYKDVQYVKGIGPKKADKLNKLGIFTLKDLLYYFPRQFEDRN
                     NLKKIAQLEDGEKVTIKAVISSINTFSPKEGMTLTKIDVKDETGSAKLVFFNKSYIKN
                     TFRPGDSILVFGKVKKKFNNLELTSCELEYLTNSPKNTCRFMPVYQLTYGVTNKEIMS
                     IIRTVLEDKELIIQEYMPQRIIEKYRLCSIDFAVRNIHSPSSKESLKIALYRIVFEEL
                     LILQLGLFVFKSGRNKEDGIKFETSKDLKKIISALPFKLTKAQNRALDEIIQDMNLEK
                     IMNRLVQGDVGSGKTVVALLALANCVLNGYQGALMAPTEILAGQHYISLTESLKDFGI
                     NVGLLIGSLTKKQKDTVLEQIKNNEIDILIGTHALIEDKVEFNNIGLVITDEQHRFGV
                     MQRSKLSLKGANPDILVMTATPIPRTLALILYGDLDISIIDELPPGRQPIETIAIEKS
                     KRDRAYNNLVRREVESGRQVYIVCPLVEESEAIEAKSAVELVEELRAEYFHDLRLGLL
                     HGKMKSSEKDEVMRLFKDKEIDILVSTTVIEVGVNVPNATLMIIENAERFGLAQLHQL
                     RGRVGRGSHKSYCVLIYDSKTDVCRQRMAIMEETNDGFKISEKDLEIRGPGEFFGTRQ
                     HGLPELKVANLFKHIKILKLAQQEARYILGEDNNLQLKENMALKKEIIDKFKDTLKEI
                     SLN"
     gene            4405..4959
                     /gene="rsmD"
                     /locus_tag="JAM15_17605"
     CDS             4405..4959
                     /gene="rsmD"
                     /locus_tag="JAM15_17605"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HAT6800060.1"
                     /translation="MRVISGKARGLKLNTPKNEDVRPTTDRVKESLFNMINSYIMESE
                     VLDLFAGTGSLGIECLSRGAKSCTFVDISKESIDIVKSNIKKARVESESIILNLDFKT
                     AIDKLKLQNSKFDIIFMDPPYYKNMFIEAIEKIDNSNLLNEDGIIVVEHDTNDLFPDK
                     ICKLEKTRDKKYGNTTLTFYKMEA"
     gene            4961..5458
                     /gene="coaD"
                     /locus_tag="JAM15_17610"
     CDS             4961..5458
                     /gene="coaD"
                     /locus_tag="JAM15_17610"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HAT6800061.1"
                     /translation="MENKPRKAIFAGSFDPITNGHLDIICRASKLFDELQIGVLNNPN
                     KKGLFSFDERVKLIEKSTSHLNNIKVVTFDGLLINYCQENGIGALVRGVRSGADVDYE
                     LQMAHMNRELNPDIETIILPSCTKYSFISSSLIKEVLLFDADIKNLVPKIVLEELKKK
                     TSGGN"
     gene            5462..5986
                     /locus_tag="JAM15_17615"
     CDS             5462..5986
                     /locus_tag="JAM15_17615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800062.1"
                     /translation="MKIDLEMIELFEQLEEIFRSASTIPFSHKCTVDKDEVLAIINDI
                     RTLIPEEVTQAVWINKERNKIISQAKQDATNIVEQAKKEAERIQQEYQDNIEELKKNS
                     EDVVKAYVESSEPVVQADQRAKDIVDRAERIANEIRIGSIEYAEDVLSSVEYNLREIL
                     EEVKRDKAELRPKK"
     gene            6330..8249
                     /locus_tag="JAM15_17620"
     CDS             6330..8249
                     /locus_tag="JAM15_17620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HAT6800063.1"
                     /translation="MKERAKKILDFIIKNNNVTSQELQERFNVSKRTIYYDILAINEQ
                     LGKSGNIKNVKHKFIFEGNLCDARKIISTEEDKFLDSDYRKTFILNKILLGEKISIEK
                     LTNEMLLSKNTVVQTITDVKKYLQTMGLRLEYKGKYKIIGDEYVIRELFLIIVQENVL
                     EINSISEEVSSFDTKGHIKLTDYSLLNLTKFVEFLNKRIRDGKTLYSYKYLNEAKKIS
                     YFSNCKELLCEEANENEQAYICTYISSLPSLNSEVKEDVVEEYVDKLIDKFEVNTAIK
                     LESKHEFKKNILRHLHSSYNRIRFKFPIRNPMLDETKYKHESLYKIIKSIIENEEEFP
                     VFEGIREEEIGFIAAYFGGYLRGSRDNGLRRNKVLLVCPNGLMVSKSLEIQLYKYIPT
                     IEIVGIVSIKQLKEVNVYYDYIITTIDIQNVNNVIVVNPLLTSSDVQLLMNKLISVKE
                     NEKYFNLELIIQAIRKNGVINNEEALKADLLNIIHKIDEGEMYQPMLKELINAERVNI
                     IKSVRDWKEAIKIASKPLLEDNSIEELYIENMIKSVEKYGPYIVLADRFALPHASSKE
                     GVNKLAMSLLIVEDEVDLLGKPVNIFMVLAAVDNTTHIRALASLSEMMYEEENVKLII
                     NGDKSSILELINKQN"
     gene            8262..8549
                     /locus_tag="JAM15_17625"
     CDS             8262..8549
                     /locus_tag="JAM15_17625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAT6800064.1"
                     /translation="MKILAVCGFGVGSSMVLKMTIQKALKQLGIECEVENTDINSARG
                     ADCDCIFTSQELLNELKGTCNVDVYPVKKYMDLAEVTEVVQTFLSDKNDKK"
BASE COUNT         3604 a          885 c         1605 g         2590 t
ORIGIN      
        1 tatttggaaa ataattatta tttttctttg aatatatata ctatagaaga aattttatcc
       61 aaaaactttt ctaggtttaa attataccat atttatagta tgatatgatt ataattttat
      121 ataataaata agtaaaaata gtaaaaaata aattaagaaa tgtttttaat aaaaataagc
      181 ttaagggggt caaccatgag tgcaaaggta acgaatcaat atggaaatat agaaatagat
      241 aatcaagtaa tagctcaagt cgtatataga gctgcaatgg aaagttatgg cttagtaggt
      301 ttagcatata agtctaaagg aatagtagag ctattaaaag gcgagaacgc aactaaaggt
      361 gtaagagttg aggaagtaga agaagatgcc atagcaatcg aactttatgt tataatacaa
      421 tatggtacaa atatatctac tgttgccaat aatataatag atagagtaaa gtatgtagtt
      481 gaaaaaatga ctggcgtaag agttactaga attgatatta atgtacaagg aataagagtt
      541 aagtaatttc ataggaggaa acaaatgatt caatatatag atggtaaaag gttaagggag
      601 atgtttattt caggtgcaaa caatctccaa aacaataaag agttagttga caagttaaat
      661 gtattccctg taccagatgg agatacagga actaatatgt cattaacaat atcttatgcc
      721 ttaaaagaat tagcaaaagt tgaaaatgat aatatatcag atatcggaaa agcattatct
      781 aaaggttctt taatgggagc tagaggaaac tcaggagtta tactttcaca aataatcaga
      841 ggtatagcta aatctataga aggaaaaagt aaattatcaa cagaagattt agcaaaagct
      901 tttaaaaatg gttcagacac agcatataaa gctgtaataa aaccaattga aggaactata
      961 cttactgtag ttagagaaag tggagagttt gcaataaaaa ctgcgaaaaa agagaaagat
     1021 gtagtaaagt ttttaagtat gcttgtgaag gaatcaaatt cttcattaga aagaactcca
     1081 gaccttctaa agaatctaaa agaagctggt gtagttgact ctggtggaaa gggtcttgta
     1141 cttatatatg aaggaatgtt agcttctata aaaggcgata acatagaaac aaaaaatgtt
     1201 gacctagata ctaatatttc aacaagtatg gattttgcaa agagtactac tagcacagat
     1261 gatataaaat attgctattg tacagaattt attttagaaa gttctaaggt agaagatact
     1321 aaaataagag acataatgat ggcttatggt gatagcctag cagtagttgg agatgatgga
     1381 gtcataaagg tacatgtaca cactaatgac ccaggaaatg tacttcaaga agctctaaag
     1441 tacggccaat tattaactat aaaaatagaa aatatgaagt tacaacatga aaatacatta
     1501 ctggatgtag aagaaaagaa agaaaatgat agtgaacctt tagaagaaga aaaagagttt
     1561 gggtttatag ctacttctat gggtgaaggt ttggcaaata tatttaaaga tttcggagtt
     1621 gaccatataa tagaaggtgg tcaaactatg aatccaagta ctgaagattt tatgaatgct
     1681 ataaagcata taaatgctaa aaatatattt attttcccaa ataacagcaa tataataatg
     1741 gctgctaatc aggcaaaaga attgagtgat aaaaatataa tagttatacc tacaaaaaat
     1801 acgcctcaag gatttgctgc attagtaact tttaatggag aattaagcga agatgaaaat
     1861 aaagaagcta tgatgaatgc tttaaactca gttaaatcag gtcaagtaac ttttgctgtt
     1921 agggatacag tgatgaacga aattgatgtt aaagaaggta atataattgg aattgcagaa
     1981 gggaatttat tatcagcagg agattatgtg gatgaagtaa catcaaacct tattgaaaag
     2041 ttggttgatg aagatactgc tataataaca ttattctttg gtgaagatgt tacagaatct
     2101 caagcaaatg aactacgtac ttctttagaa gaaaagtttg aagatgtaga tgtagagtta
     2161 tattatggag gacaacctct ttattattac ttaatttcag ttgaataatg attataagaa
     2221 cctgtatgac caagtagctt ttataaaatt ggttgtacag gatttttgtg tagtaggtga
     2281 tatatttgtt ggatttatat aaagatgttc aatatgttaa gggaatagga cctaaaaaag
     2341 cagataaatt aaataaactg ggtatattta cactaaaaga cctattgtat tattttccaa
     2401 gacaatttga agatagaaat aatctaaaga aaatagcaca attagaagat ggtgagaaag
     2461 ttacgataaa agcagtaata tcaagtataa atacatttag cccaaaagaa ggtatgactt
     2521 taacaaagat tgatgtaaaa gatgagacag gctcggctaa attagtgttt tttaataaga
     2581 gttatataaa aaatactttt cgtccaggag attcaatatt agtttttggg aaggttaaga
     2641 aaaaatttaa taacttagaa cttacatcat gtgaattaga atatcttact aattcaccta
     2701 agaatacatg tagatttatg cctgtgtacc agcttacata cggtgttaca aataaagaaa
     2761 ttatgagtat aattagaaca gtacttgaag ataaagaatt aattatacaa gaatatatgc
     2821 cacaaagaat tatagaaaaa tataggctat gtagtataga ttttgcagtt agaaacatac
     2881 attcaccaag tagtaaggaa tcattaaaaa tagctttata tagaattgta tttgaagaat
     2941 tacttatact acaactaggg ttgtttgtat ttaaaagtgg cagaaataaa gaagatggaa
     3001 taaagtttga aacaagtaaa gacttaaaaa aaataataag tgctttacca tttaaactga
     3061 ctaaagctca aaacagggca ttagatgaaa ttatacaaga tatgaattta gagaaaataa
     3121 tgaatagatt ggtacaaggt gatgtaggga gtggtaaaac agtagtagct ctcttagcac
     3181 ttgcaaattg tgttttaaat ggttatcagg gcgctttgat ggcacctaca gagatattag
     3241 cagggcaaca ttatatttca cttactgagt ctctaaaaga ttttggaata aatgtaggtc
     3301 tattaatagg tagtcttaca aaaaaacaaa aggatacagt attggaacaa ataaagaata
     3361 atgagattga tatattaata ggtacacatg cactaattga agataaggtt gaatttaata
     3421 atattggttt agttataaca gatgaacaac atagatttgg tgttatgcaa aggagcaaac
     3481 tttcattgaa aggagcaaat cctgatatat tagtaatgac agcaacacca ataccaagaa
     3541 ctttagcact tatactctat ggagatttag atatttctat tatagatgaa cttcctccag
     3601 gaagacagcc aatagaaaca attgctattg aaaaaagtaa gcgagataga gcatataata
     3661 atcttgtaag aagagaggtt gaatcaggaa gacaagtgta cattgtatgt cccttggtag
     3721 aagaaagtga agccatagaa gccaaatcag cagttgaact tgttgaggag ttaagagcgg
     3781 aatattttca cgacttaagg cttgggttgc ttcatggtaa aatgaagtca agtgaaaaag
     3841 atgaagtaat gagacttttt aaagataaag aaatagatat tttagtttca acaacagtaa
     3901 tagaagttgg tgtcaatgtg ccaaatgcaa cattaatgat aatagaaaat gcagaaagat
     3961 ttggacttgc acaattacat cagcttagag ggcgagttgg aagaggtagt cataaatcgt
     4021 attgtgtact aatttatgat tctaaaacag atgtatgtag acaaagaatg gctataatgg
     4081 aagagaccaa tgatggtttt aagatttcag agaaggattt agaaataaga ggacctgggg
     4141 aattttttgg gacaaggcag catggtcttc cagaacttaa ggtagcaaac ttatttaagc
     4201 atataaaaat actgaagtta gcacagcaag aagctcgata tatattgggt gaagataata
     4261 atctacaatt gaaagaaaac atggcactca aaaaagaaat tatagataaa tttaaagata
     4321 cattgaaaga aatttcatta aattaatttt aaattgtgtt aaaatattac taatgtaata
     4381 atgtgctgaa gggagattgt catattgaga gtaatttcag gaaaagcgag aggattaaaa
     4441 ctaaatactc caaaaaatga agatgtaagg ccaactacag atagagtaaa agagtctcta
     4501 tttaatatga taaattcata tataatggaa agtgaagttc tggatttatt tgctgggact
     4561 ggttctttag gaatagagtg cttatctagg ggtgccaagt catgtacttt tgtagatatc
     4621 agtaaggaaa gcatagatat tgttaagtcc aatataaaaa aggcaagagt tgaaagtgaa
     4681 agtattattt taaaccttga ttttaagact gcaatagata aacttaaatt acaaaatagt
     4741 aaatttgaca taatttttat ggaccctccg tattataaaa atatgtttat agaagctatt
     4801 gaaaaaattg ataattctaa tctattgaac gaagatggaa taatagttgt agaacatgat
     4861 acgaatgatt tatttccaga taagatatgt aaattggaga aaactagaga taagaaatat
     4921 ggaaatacta cattaacttt ttataagatg gaggcataat atggaaaata aacctagaaa
     4981 agctatattt gcaggaagtt ttgacccaat tactaatgga catttagata ttatttgcag
     5041 ggcttcgaag ttatttgacg aattacaaat aggagtatta aataatccta ataaaaaggg
     5101 tctatttagc tttgatgaaa gagtaaaact tatagaaaaa agtacaagcc atttaaataa
     5161 tataaaagtt gtgacttttg atggtttatt aataaattac tgtcaggaaa atgggattgg
     5221 agcattagtt agaggtgtga gaagtggtgc tgatgttgat tatgaacttc agatggcaca
     5281 tatgaataga gagcttaatc cagatataga gactataatt ttaccaagtt gtacaaaata
     5341 ttcatttata agttcatctt taataaaaga ggttttgctc tttgatgctg atataaaaaa
     5401 tttggttcca aagattgttt tggaagaatt aaagaaaaaa actagtgggg gtaattgata
     5461 tatgaagata gatttagaaa tgattgaact atttgagcag ttagaggaga tatttagaag
     5521 tgcttctaca atccctttct cacataaatg cacagtggat aaagatgagg ttttagcaat
     5581 aattaatgat ataagaactt taataccaga agaagtaaca caggcagtat ggattaataa
     5641 agaaagaaat aaaataataa gtcaagctaa gcaagatgct acaaatatag ttgaacaagc
     5701 gaaaaaagaa gctgagagaa tacaacaaga atatcaagat aatatagagg aattaaagaa
     5761 aaattctgaa gatgtagtaa aggcatatgt agaatccagc gaacctgttg ttcaagcaga
     5821 ccaaagagca aaagatatag ttgatagagc tgagagaata gccaatgaga taagaattgg
     5881 gtcaattgaa tatgcagagg atgtgctttc tagtgttgag tataatttaa gagaaatatt
     5941 agaagaagta aaaagagata aagctgaact tagacctaaa aaataaattt taaataaata
     6001 aaaatggagc tatcacacaa aaaattccaa tttatgtgtg atagctctct tttaatatag
     6061 caattttttg ttatataatt gtgcttttta gattacttat atcttatttt gatattataa
     6121 tgcagtttaa tcttttattt gttgaaatca acttatttat ttgtataaat aatataggtt
     6181 attttcaaat ttttttaata attttaccac tgtcttcttt tagattagag ttagactgtg
     6241 caaaattata aaataatact aaatcatgtg caattatttg gtatggcact acatgtagaa
     6301 aatatagata ataaaattaa ggaggtagta tgaaggaaag ggctaaaaaa atattagatt
     6361 ttattattaa aaataacaat gtaacatcac aagaactaca agaaaggttt aatgtttcaa
     6421 agagaactat ttattacgat attctagcta taaatgaaca actaggaaaa agtggtaata
     6481 taaaaaatgt aaaacacaaa tttatatttg aaggtaattt atgtgatgca aggaaaataa
     6541 tttcaactga agaagataaa tttttagata gtgattacag aaaaactttt atattaaaca
     6601 agatattact tggcgaaaaa atatcaatag aaaaactaac aaatgaaatg ttactttcaa
     6661 aaaacacagt agtacaaaca ataactgatg taaaaaaata ccttcaaaca atggggttaa
     6721 gattagagta taagggaaag tacaaaatta taggtgatga atacgttatt agagagctgt
     6781 ttctgataat tgttcaagaa aatgtactgg aaattaattc tataagtgag gaagtaagta
     6841 gtttcgatac aaaaggacat ataaaactta ctgattattc tttattaaat ctaactaagt
     6901 ttgtggaatt tctaaataaa aggataagag atgggaaaac attatactca tataaatatc
     6961 taaatgaagc taaaaaaatt agttacttta gtaattgtaa agaactttta tgtgaagaag
     7021 ctaatgaaaa tgaacaagcc tatatatgca cttatataag ttcacttccc agcttaaata
     7081 gtgaagttaa ggaagatgtt gttgaagaat atgtagataa acttatagat aagtttgaag
     7141 taaatacagc aataaaatta gaaagtaagc atgagtttaa gaaaaatatt ttaaggcacc
     7201 tccactcttc ttacaacaga atacgattta agtttcctat tagaaatcca atgttagatg
     7261 agactaagta taaacatgag tcactttata aaattataaa atcaattata gaaaatgaag
     7321 aagagtttcc tgtatttgag gggataagag aagaagagat aggatttata gcagcgtatt
     7381 ttggagggta tttaagaggg tctagggata atggcctaag aagaaataaa gtcttactag
     7441 tttgtcctaa tggtcttatg gtatcaaaga gtttggaaat acaactatat aaatacatac
     7501 caaccataga aatagtaggt atagtgtcca ttaagcaact aaaagaagta aatgtatact
     7561 acgattacat aattacaact atagatatac aaaatgtaaa caatgtaatt gttgtaaatc
     7621 ctcttttaac atcatcagat gttcaattac ttatgaacaa actaataagt gtaaaagaaa
     7681 acgagaagta tttcaatctt gaattaataa tacaagctat aagaaaaaat ggagttatca
     7741 ataatgaaga agcactaaaa gctgatttat taaacataat acacaagata gatgaaggag
     7801 agatgtatca accaatgtta aaggaattaa ttaatgcaga aagggtcaat ataataaaaa
     7861 gtgttagaga ttggaaagaa gcaataaaaa tagcctcaaa gccattgtta gaagataact
     7921 ctatagaaga gttatatata gaaaatatga taaagtcagt tgaaaaatat ggaccatata
     7981 ttgttttagc tgatagattt gctctaccac atgcaagttc taaagaagga gtaaacaagc
     8041 ttgctatgtc tttactaata gtagaagatg aagttgattt attaggaaaa ccagtaaata
     8101 tatttatggt attagctgct gtagataaca ctactcacat tagagcatta gcatcactat
     8161 cagagatgat gtacgaggaa gaaaatgtaa aactaataat taatggtgat aaaagttcaa
     8221 tactagaact tataaataag caaaattagg aggaatgaaa aatgaagata ttagcagtat
     8281 gtggttttgg tgtaggttca tcaatggtat taaaaatgac aatacaaaag gctctaaagc
     8341 agttaggtat agaatgtgaa gtagaaaata cagatataaa ttcagctaga ggtgctgatt
     8401 gtgactgtat attcacaagt caagaattgt taaatgaatt aaaaggaact tgtaatgtag
     8461 atgtatatcc agttaaaaag tacatggatt tagcagaagt cacagaagtt gttcaaactt
     8521 ttttaagtga taaaaatgat aagaaatagt ataagtttta aaaagtaaat ttaagttaat
     8581 cagaataaaa taaaaactta ctaaattcaa aaatagtaag aaagagagga gggatttagt
     8641 ggtagaaaac ttaaacagtt gacctatcac taaaaaatat aatg
//
LOCUS       DACTZW010000126         8183 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.127, whole genome shotgun sequence.
ACCESSION   DACTZW010000126 DACTZW010000000
VERSION     DACTZW010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8183)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8183)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8183
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.127"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            <1..471
                     /locus_tag="JAM15_17630"
     CDS             <1..471
                     /locus_tag="JAM15_17630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAT6800065.1"
                     /translation="ISKYKECYKPSIEQGAVVDMKVKTVLIVSNVNNIELKIDPTIIF
                     ATLKDIQELDTKIDTTKTELTSNIETTKTEINTKIGDTTLLETTDKTNIVSAINEVKT
                     SVDSIETTAEKTSYNNATSNLTATTVQGAIDEVVRKIENFNEININTINNILPI"
     gene            485..2164
                     /locus_tag="JAM15_17635"
     CDS             485..2164
                     /locus_tag="JAM15_17635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800066.1"
                     /translation="MAKVYDFNYIHGEQEVVLPPGKYLLECWGAAGGGGIRIVDFNLR
                     SKGGYSKGELTLRKETTLYVYAGSKGSNYGSTFNGGGKAMMHEGASGGGVLYCNGGGA
                     TDIRLIGGSWDNEQSLLSRIIVAGGGGRNNFETKGGDGGGDAGGDGSKADSKGTQTNG
                     GKGEVGLDGSFGKGGSAVSASSGENYGGGGGGWYGGGSGYNAGGGSGYVLTENSYKPA
                     GYIPTKEYWLENTSMTVGGGIAEENGKARITLLQGLPFLVISSYTSQQAIFTAGHTEE
                     NKLSKIECFIDDVLKETFTTDLYLEKTINYTLEDNALHTLKIVVTDINNITYEQVVTI
                     SKSIMPLPTDANLQDISSKLTEIGESFKNGKTSIINTLALKNIEASLNNTLVELSEKI
                     KVGFDSGDASLQDLMNQLTQANNTITQLNSKYKYASGTTTVLTEVKGIVNRYNVPSIY
                     RFGEFSKWVKVTGLNFVPNIFISFRDFDTDSYHYVNIVISFVGIFSSDFAITALLSFR
                     RTSGETSYKATLCDIVEVNSQDVYVNSSGINLPECVLSNYTTRNWYAIKFK"
     gene            2178..2471
                     /locus_tag="JAM15_17640"
     CDS             2178..2471
                     /locus_tag="JAM15_17640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800067.1"
                     /translation="MNRANRIICNQEGKILLQTGEATGDLLEHDEITELHCIDVPYGS
                     IDYTRNRIIGINIETKQPILEEIPVYITDEEKRIQELENQILLNENEKVGGLL"
     gene            2471..2653
                     /locus_tag="JAM15_17645"
     CDS             2471..2653
                     /locus_tag="JAM15_17645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800068.1"
                     /translation="MNINNVVVRILAERILNRGLNPLKNQEFQLDDVTNIDYRKAVED
                     YIIEHSGVVEGTEPTI"
     gene            2690..3256
                     /locus_tag="JAM15_17650"
     CDS             2690..3256
                     /locus_tag="JAM15_17650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800069.1"
                     /translation="MTFKELVNKVRNLVLEAKKVTIEDTENKFTSENVEGALKECIDR
                     ADSAFQSADSGKILLSTAIGSPATSEQTFQDYANYITGFKSNISNLETQLKSKYSIRY
                     GPIDGYDGNPFSANFGKSASYLIVYVYFRRNVYYYNPSGSSLGSNTGGSERAWITIDS
                     NKTGFSVHSYDTSYEPYPFTGYYIACFA"
     gene            3288..3578
                     /locus_tag="JAM15_17655"
     CDS             3288..3578
                     /locus_tag="JAM15_17655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800070.1"
                     /translation="MEEISINLLCAVAGVVISYLAFRNNSNRKIQDDTETTTKLEQQI
                     TFLCENVRDIKHDVAKFNTSFLDISERVAKIEASTKQAHLRIDEIVNRIGGK"
     gene            3582..3839
                     /locus_tag="JAM15_17660"
     CDS             3582..3839
                     /locus_tag="JAM15_17660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin"
                     /protein_id="HAT6800071.1"
                     /translation="MDNLISFIPEQLLILVAALSIIGKGCKKYKQLDNKYIPVVLLAL
                     GIGFSVWMLGLNPTSVLQGVICWGISIGINQTYKQLKDGEK"
     gene            3839..4645
                     /locus_tag="JAM15_17665"
     CDS             3839..4645
                     /locus_tag="JAM15_17665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAT6800072.1"
                     /translation="MKIAIVPGHTLSGKGTGATGYIDEGKENRILTDLIVKWLKQGGA
                     TVYTGKVDKSNNYLAEQCEIANRQNVDLAVQIHFNANKTTLNPMGTETIYKTNNGKVY
                     AERVNEKLATVFKNRGAKSDARGLYWLSHTKAPAILIEVCFVDSKADTDYYIKNKNTV
                     AKLIAEGILNKNINNKEDEEGKIMYKHTIVFEGEVDKITATILGWGYNDGKILICDIK
                     DYIPGQTENLYVVGGRACNKIGSITKEKYTMIKGNDRFDTLHKALDFIDR"
     gene            5055..5198
                     /locus_tag="JAM15_17670"
     CDS             5055..5198
                     /locus_tag="JAM15_17670"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800073.1"
                     /translation="MMNKELVYGEIDEKKLDVSRISHEELKALFNLMNGKPDSMLRIF
                     QEM"
     gene            5279..6085
                     /locus_tag="JAM15_17675"
     CDS             5279..6085
                     /locus_tag="JAM15_17675"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800074.1"
                     /translation="MNISVKFDNNTFKEFSDWIEFQNCNWSSSHYLENITIKYDFFVD
                     FKEYGVPQRHTLVIRLSSGMKPQQILQLIVSGQIEEIDSIDKSLSPVTCKVDFTNHLL
                     GDELINIIEEWDKSIQKVVSESGKTMKFIRKYRKGISAVIENIIPLFGLIVLVSIVNF
                     NLSHFNIDTLVQLSISHIQKLIMLTLLFSLIYKVIKNIGEFLSNKFLTEIYEYGDTHI
                     FNITNGDKIKREKLDIKNKKHEKGIKSSLSLTILINVICGIVATYICTIF"
     gene            complement(6681..6869)
                     /locus_tag="JAM15_17680"
     CDS             complement(6681..6869)
                     /locus_tag="JAM15_17680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800075.1"
                     /translation="MTKTILCNYCNKGIDKDDNKYITFHKKSHMKTNICINCALNLID
                     KDKLNENIINNQHSYSKK"
     gene            7129..7278
                     /locus_tag="JAM15_17685"
     CDS             7129..7278
                     /locus_tag="JAM15_17685"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800076.1"
                     /translation="MEIVAVYYIAKFLLDIYKVKSHSKSEAKSGFIFNLTINKLIVKI
                     KYKKY"
     gene            7814..>8183
                     /locus_tag="JAM15_17690"
     CDS             7814..>8183
                     /locus_tag="JAM15_17690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HAT6800077.1"
                     /translation="MEQQEVVNKLRRGELMLMEYLWRKKSILSKKEIIEAMKDRYKWR
                     KSTTEILLKRLVKMKTLKKKRIGFELNYEVLVTKKEYLNARKEDRQVTKYDSFFIRMF
                     TTMHKKEKMTEEQIKKYIENM"
BASE COUNT         3307 a          865 c         1370 g         2641 t
ORIGIN      
        1 atctctaaat ataaagaatg ttataaacct tctatagaac aaggtgcagt ggtagacatg
       61 aaggttaaaa ctgtgcttat tgtatctaat gtaaataata tagaactaaa aattgaccct
      121 acaataattt ttgctacact taaagatata caagaattag acactaaaat agatacaact
      181 aaaacagaat taacaagcaa catagaaact actaagacag agattaacac taagataggt
      241 gatacaacat tacttgaaac aacagataaa acaaatatag ttagtgcgat taatgaggta
      301 aaaactagtg tagatagtat agaaacaaca gcagagaaaa caagttataa taatgctact
      361 agtaatctta ctgctactac tgtgcaaggg gcaatagatg aagttgttag aaagatagaa
      421 aattttaatg aaattaatat aaatacaata aataatatat tgcctatata gaaaggagaa
      481 gaagatggct aaggtttatg attttaatta tatacatgga gaacaagaag ttgttttgcc
      541 accaggaaag tatttacttg aatgttgggg agcagctggt ggtggaggca ttagaatagt
      601 tgactttaac ttacgttcaa aaggaggata ttcgaaagga gaattaactt taagaaaaga
      661 aacaacattg tatgtttacg ctggttcgaa aggttcaaat tatggctcta catttaatgg
      721 tggaggaaaa gcaatgatgc atgaaggagc ttctggtgga ggagtactgt attgtaatgg
      781 tggcggagca acagatataa gacttattgg tggttcttgg gataatgaac aaagtctttt
      841 atctagaata attgtagcag gtggaggtgg tagaaataat tttgaaacaa aaggtggaga
      901 tggtggtgga gatgctggag gtgatggttc taaagcagat agcaaaggaa ctcaaactaa
      961 cggtggtaaa ggcgaagtag gattagatgg ctcttttgga aaaggcggaa gtgctgtatc
     1021 agctagttca ggagaaaatt atggcggtgg aggtggagga tggtatggag gtggaagtgg
     1081 ttataatgca ggtggtggaa gtggctatgt tttaacagaa aatagttata aaccagctgg
     1141 atatatacca accaaagaat attggctaga aaatacttct atgactgttg gtggaggtat
     1201 tgcagaagaa aacggaaagg ctagaataac actattgcaa ggtttgcctt ttctcgttat
     1261 tagttcttat acatcgcaac aagctatttt tacagcagga catacagaag aaaataaact
     1321 atctaaaatt gaatgtttta tagatgatgt attaaaagaa acttttacta cagatttata
     1381 cttagaaaaa actattaact atacacttga agataatgca cttcatacac ttaaaatagt
     1441 tgttacagat attaataaca taacttatga gcaagttgtt actataagta agagtataat
     1501 gccacttcca acagatgcta acttacaaga catatcctct aaattaacag agattggaga
     1561 aagttttaag aatgggaaaa caagcattat aaatacttta gcattaaaga atatagaagc
     1621 aagcttaaat aataccttag ttgaattgtc agagaaaatt aaggtaggtt ttgatagtgg
     1681 agatgctagt ttacaagatt tgatgaatca attaacacaa gctaataata ctataactca
     1741 gttaaattca aaatataaat atgcaagtgg tactacaact gttttaacag aagttaaagg
     1801 aattgttaat cgttataatg ttccaagtat ttatagattt ggagaattta gtaagtgggt
     1861 taaagttact ggattgaatt tcgtgcctaa catttttatt tcttttagag attttgatac
     1921 agattcttat cactatgtta atattgtcat ttcttttgtt ggtattttta gttcagattt
     1981 tgccattact gctcttttaa gttttagacg aacttctggt gaaactagtt ataaggctac
     2041 tctttgtgat atagttgaag taaattcaca agatgtttat gttaatagca gtggtatcaa
     2101 tctgcctgaa tgtgttttaa gcaattatac tactcgtaat tggtacgcta taaaatttaa
     2161 ataaacgagg tgataaaatg aatagagcaa atagaattat atgtaaccaa gaaggtaaaa
     2221 tattactcca aacaggagaa gcaacaggtg atttattaga gcatgatgaa ataacagaat
     2281 tacattgtat tgatgttccg tatggaagta tagactatac aagaaataga attataggta
     2341 taaatataga aactaaacaa ccaatcttag aagaaatacc agtatatata acagatgagg
     2401 aaaaaagaat acaagagtta gaaaatcaga ttttactaaa tgaaaatgag aaggtaggag
     2461 gattattata atgaatataa acaatgttgt agtaagaata ttagcagaaa ggatattaaa
     2521 cagaggatta aatcctttga aaaatcaaga atttcaacta gatgatgtaa ctaacataga
     2581 ttacagaaaa gcagtagaag attatattat agagcatagt ggagtagtag aaggaacaga
     2641 accaacaata tagaggttct ttttttattt gtgaaaagag gtgatttaat tgacttttaa
     2701 agagttagtt aataaagtta gaaatcttgt attagaagca aagaaagtaa ctatagaaga
     2761 cacagagaat aaattcacta gtgaaaatgt agaaggagca ttgaaagaat gtatagatag
     2821 agccgactcg gcttttcaaa gtgccgatag tggcaaaata cttttatcga ctgctatcgg
     2881 ctctcctgct acatcagaac aaacatttca agattatgcg aactatatta caggatttaa
     2941 gagcaatata agcaatttag aaactcaatt gaaaagcaaa tattctatta gatatggtcc
     3001 tattgatgga tatgatggta atcctttttc tgctaatttt ggcaagagtg caagttacct
     3061 tattgtctat gtttacttta gaagaaatgt atattattat aatcccagtg gtagttcttt
     3121 aggaagtaat acaggaggct ctgaacgtgc atggattact atagatagta ataaaactgg
     3181 tttttcagtt cattcatatg atactagtta tgagccatat ccttttacag gttattatat
     3241 tgcttgtttc gcataataaa ttatattatt taaaactagg aggatgtatg gaagaaatta
     3301 gcataaatct actatgtgca gtagcaggag ttgtaatatc ctacttagca tttagaaata
     3361 actcaaacag aaagatacaa gatgatacag aaacaactac aaaattagaa caacaaataa
     3421 cttttctgtg tgagaatgta agagatataa agcatgatgt agcaaagttt aatactagtt
     3481 tcttagatat tagtgaacga gttgcaaaaa tagaagcaag tacaaaacaa gcacatctta
     3541 gaattgatga aattgtaaat agaattggag gaaaataaaa gatggataat ttaataagtt
     3601 tcataccaga gcagttgcta attttagtag ctgctctctc tattataggt aaagggtgca
     3661 aaaaatataa acaactagat aataaatata ttccagtagt gttgttagca cttggaatag
     3721 gtttttcagt atggatgtta ggattaaatc caacctcagt attacaaggc gtaatttgtt
     3781 ggggtatatc aataggtata aatcaaactt acaaacagtt gaaggatggt gaaaaataat
     3841 gaaaatagca atagtaccag gacacacttt aagtggaaaa ggaacgggag caactggcta
     3901 tatagatgaa ggaaaagaaa atagaatctt aactgattta atagtaaaat ggttgaaaca
     3961 aggtggagct actgtatata ctggaaaagt agataaatct aataactatt tagcagaaca
     4021 atgtgaaatt gccaataggc aaaatgtaga cttagcagta caaatccatt tcaacgcaaa
     4081 taaaacaact ctaaatccta tgggtacaga gacaatatac aaaactaata atggtaaggt
     4141 atatgctgaa agagtcaacg agaaactagc aacagtattt aaaaatagag gtgcaaaatc
     4201 ggacgcaaga ggtctttact ggcttagtca tacaaaagca ccagcaatat taattgaagt
     4261 atgtttcgta gacagtaaag cagatacaga ttattatatt aaaaataaaa atacagttgc
     4321 aaaattaata gcagagggca tattaaataa aaatatcaat aacaaagaag atgaagaagg
     4381 aaagattatg tacaaacata caatagtttt cgagggagaa gttgacaaaa ttactgcaac
     4441 tatacttggt tggggatata atgatgggaa aatattaata tgtgatataa aagattatat
     4501 accaggtcaa acagaaaatt tatatgttgt aggcggtaga gcatgtaata agataggttc
     4561 tataactaaa gaaaaataca caatgataaa aggtaatgat agatttgata cacttcataa
     4621 agcattagat tttattgata gatagaaata tagatattaa taccttgtac tttatatcta
     4681 tattttattt acagtttgct aactatataa taaacaaaaa atgatatatt agaaatatat
     4741 aagttgcttg caaaaataaa actaagatgg acataagtta taaatttaat tgtaagtata
     4801 aatactacaa aatagaaaat aattagattg aataaattgg ttgcatatgc agaattattt
     4861 attatatgaa aatataaaga tatgctatat ttttataact tactctattt ataaagacag
     4921 tatatggaaa aaattggttg aaaaaagata aaaccaatat tattataata gataagaggg
     4981 tataaatatg atttattgtc atattttaga aattttatta tataaatata atgttttaaa
     5041 aatagaggag ttatatgatg aataaagaat tagtttatgg tgagattgat gaaaaaaaac
     5101 ttgatgtatc aagaataagt catgaagaat tgaaggctct attcaattta atgaacggga
     5161 aacctgatag tatgcttaga attttccaag agatgtaaat gtagaaataa aagatttata
     5221 ttctttacat gaaaaaataa aagaaaaatt acaacattat atagtagcag ctttaatagt
     5281 gaatatatca gttaagtttg ataacaatac tttcaaagag ttttctgatt ggatagaatt
     5341 tcaaaattgt aattggtcta gctcccacta tttagaaaat ataactataa agtatgattt
     5401 ttttgttgat tttaaagaat atggggttcc tcagagacat acattagtaa taagactatc
     5461 ttcaggaatg aaacctcaac agatattaca gctcatagta agtggtcaaa tagaagaaat
     5521 agattctata gataaaagct tatctcctgt tacttgcaaa gttgatttta ctaatcatct
     5581 attaggtgat gaattaataa atataataga agaatgggat aaatcaatac aaaaagtagt
     5641 ttctgaatca ggaaaaacaa tgaaatttat tagaaaatat agaaaaggta tttctgctgt
     5701 tatagaaaat atcataccac tttttggctt aattgttttg gtaagtatag ttaattttaa
     5761 tttgtcgcat tttaatatag atactttagt tcagttaagc ataagtcata tacaaaaatt
     5821 aatcatgctt acattgcttt ttagtcttat ttataaagta ataaaaaata ttggagaatt
     5881 tttatcaaat aagtttttga cagaaattta tgagtatggt gacactcaca tattcaacat
     5941 aacgaatgga gataaaataa aacgagagaa gttagatatc aaaaacaaaa aacatgaaaa
     6001 aggaataaaa agtagcttat cattaacgat tttaattaat gttatttgtg gaattgtggc
     6061 aacttatata tgtactattt tttaatattt gagtataatt ttaatctatt aagttcataa
     6121 ttatataaaa atatatttta aattgtattt atagctacaa aattaggggg tgtgttttat
     6181 gataaaaaaa ataattgtat tttttaaaga aagaaaacaa aaaaaagaat atttagaaga
     6241 acaagctttc tcaaataagt atatttctta tagtgactat aagtatttgt tagaacaaat
     6301 taagtagtaa aattttatga attttaaagt ataaaagcta tagcaatagt ttttatactt
     6361 tttgttttta tgtctatagc tgtaataata aaacgaacga aaattatcat actaaaacat
     6421 aagacatgct ataattgtat tagataaatg tttgaatata taccaaagta ctctttttat
     6481 aagagtgctt atttttttga aatttattaa catataaact atcaagaacc ttattcaaca
     6541 caccttaaaa ttgatttaaa tagctctttt tgatgcacaa aattaatgat ataataaaaa
     6601 agtagatatg caaccccaac gcatatttac tgagtcaaac attattatat agagcattct
     6661 tcgttgtgga gagtgctttt tcatttcttt gaataactat gttgattatt tataatattt
     6721 tcatttaatt tatctttatc tatcaaattt aatgcacaat taatacaaat gttagttttc
     6781 atatgacttt tcttatgaaa agtaatatac ttattatcat ctttatctat tcctttatta
     6841 cagtaattac ataatatagt cttagtcata tttttattcc tttcatttta tattttccat
     6901 aattaagttt aacatattta gtatatacct atgtatatat atatatatat ttaaaacaat
     6961 gttttttatt gcaatataga atatattgta taaataaaaa atatgaagaa tatatatttg
     7021 ataattgtaa aattatgtta taatttatat gtaaggaact aaatatctaa gagtggcagt
     7081 ttccacatta tgctctaacc tactttctaa tgaaaggagg tgggaagtgt ggaaatagta
     7141 gcagtttatt acatagcaaa atttttactt gatatataca aagtaaaaag ccactcaaag
     7201 tcggaagcta agagtggctt tatatttaat ttaactatta ataaactaat agtaaaaatt
     7261 aaatataaaa agtactaatt tttttcggaa actacactct cgacaataga ttatagttcc
     7321 ttatttctaa agaggtaagg gaattacagt tctcttatct ctttttgata cgattttaca
     7381 tctttattat atcgcatttt aacaaaaaat aaaactatga atcctagaaa tatattttat
     7441 tttatatcta aatatatata ttattgccca cctaaaaaac tttcataaaa tcaaaagagt
     7501 atatgttttg ataacttacc aatataactt ataactcatc ttacaagtct tatttaatat
     7561 atatttatgt cactaaattc ctttagtttt accaatttag tattattcta caattaaaac
     7621 aatacaatat aactagttat tattcaacaa gattgtttga aaattgaata attttataga
     7681 tatgaacctt attttacctt ttaaaaaata gactaaatac gtagaatgca tggtaaaact
     7741 tacctgtagt ttttgtccta aaaagctctt attattaact taaattaagt ttaatttagg
     7801 gaagtgacat aaaatggaac aacaagaagt agttaataaa ctgcgcaggg gagaactaat
     7861 gttaatggaa tacttgtgga ggaaaaagtc tattttatct aaaaaagaaa taatagaagc
     7921 aatgaaagat aggtataagt ggaggaaaag cactacagaa attcttttaa aaagattagt
     7981 aaagatgaaa acattaaaaa agaagaggat aggttttgaa ttaaattatg aagtgctagt
     8041 aactaaaaaa gagtatttaa atgctagaaa agaagataga caggtaacta aatatgatag
     8101 tttttttata cgaatgttta ctactatgca taaaaaagaa aagatgacag aagaacagat
     8161 aaaaaaatat atagaaaata tgg
//
LOCUS       DACTZW010000127         8089 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.128, whole genome shotgun sequence.
ACCESSION   DACTZW010000127 DACTZW010000000
VERSION     DACTZW010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8089
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.128"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            42..701
                     /locus_tag="JAM15_17695"
     CDS             42..701
                     /locus_tag="JAM15_17695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HAT6800078.1"
                     /translation="MLDAFITIVSSIIEIWSCKKVFDYTSQTKTDLKKLNMYFLFSVF
                     LIISSLYINIGANSRILICIFVMFVFYKSNYKVNIYKCLVISFFYWLILIGINGLSML
                     LVATVSNLDNMNVLLSGSLYRYEAIFLGKLMLGILLYVYKASFKNFKISKKEIYICIP
                     MIANLLSFFVLYDYIINLVKISPERRTAFLVIVLLLILSNISIFVLIHIILKIKIRKI
                     R"
     gene            995..1336
                     /locus_tag="JAM15_17700"
     CDS             995..1336
                     /locus_tag="JAM15_17700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator"
                     /protein_id="HAT6800079.1"
                     /translation="MKEENFINVEYEDKRFSINSKEVLYIEKQEYEVKIYTESGNYEV
                     GENAPCIRKLLKEENFFKCSNSYIVNLDKCEFYLSNNCIFVNNNFIRILGSERKKKLK
                     KKLEKLYDYED"
     gene            1487..1900
                     /locus_tag="JAM15_17705"
     CDS             1487..1900
                     /locus_tag="JAM15_17705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1653 domain-containing protein"
                     /protein_id="HAT6800080.1"
                     /translation="MLELKNNLGISERKLKYPCIYKHFKGKYYATMGLSKAIDDIENI
                     CEIYGKENLIQNRNKYKLVIRHTEREEDIYVYRDSDGNFYHKKEEDTNDLVLYKTLYD
                     DTGIFARPLDMFLEKVDTDKYVNSIQEYRFEEVYK"
     gene            2102..2743
                     /locus_tag="JAM15_17710"
     CDS             2102..2743
                     /locus_tag="JAM15_17710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAT6800081.1"
                     /translation="MGNTFYIVRHGQTDWNILGKTQGHGNSDLTPQGIEQAKELSEDI
                     GKYSIDYIFSSDLGRAMQTAQILGDKLNIEVQKTEALREMGFGVWEGLLIKEIQKDYS
                     DIYATWRNEPHLVNIPEGETLKIIKERVDAFIKELNEKYDNKNIILVTHSITLRVMLL
                     SFLESGMENIYRIKQDNTALNIVEFKDYGPVIVKMNDTSHIKNHVKINNSALE"
     gene            2767..4020
                     /locus_tag="JAM15_17715"
     CDS             2767..4020
                     /locus_tag="JAM15_17715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAT6800082.1"
                     /translation="MSKVIVVGGGASGMMAALSASKNNNEVILVERNGELGRKLRATG
                     GGRCNFTNNREIEDFFDKVVSNKKFLYSSFYTFTNKDLISYFESRNLEYKIEEENDHK
                     VYTKNDKSIEVIEVLNKDLLNHNVKIMYNKKVIDIITEEIALKDDSNKDKSKYLIKGI
                     ILDNGDKILGDKVIISTGGVSYSKTGSDGSMYKILKKHGHTLNKLYPALVPLTIEEKW
                     IKDLQGISMKNVEISCKIKKRKISKSGDMLFAHFGITGPCVLIMSSYINKIIEKEKVE
                     LNIDFLPNLSTDEISSIIRAFPNKNVLNNLKQILPQNFLKEIFSLLSLVDKKASDLSK
                     ADEIRIIEYIKNMKLTCNGTTGINTGMVTSGGISVKEINSSTMESKLVKNLFFTGEVI
                     DIDAETGGYNLQIAFSTGYLAGISV"
     gene            4066..4716
                     /locus_tag="JAM15_17720"
     CDS             4066..4716
                     /locus_tag="JAM15_17720"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HAT6800083.1"
                     /translation="MGNLVIAVDGPAGAGKSTIAKIVAKKLNINYIDTGAMYRAVTYK
                     CLKSGIDVNNEKEVIQIAENSDIDFKDNNIYLDKEVINEEIRTIEVSNNVSNVAKIKE
                     VRQLMVEVQRKIGMKSSVILDGRDIGSYVFPDADYKFFLVATPEERGNRRYKELCNKG
                     YNTTLEEVIEDIIRRDEIDSNREFAPLVKANDALEIDTTGKTIEEVVEEVVSKINL"
     gene            4767..5363
                     /locus_tag="JAM15_17725"
     CDS             4767..5363
                     /locus_tag="JAM15_17725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HAT6800084.1"
                     /translation="MNFYRFVINIFKGFSKIFFKYEVIGAENIPDRGNIVIASNHKSN
                     LDPIFLAAAIENREIAAIAKKELFKVKPLGFILKKLHVMPINREKPDVSTIKTILRSV
                     RDGYVLGIFPEGTRIKGDSFGKAKAGLSVFTIKSKSKVVPVSIISKYKLFSKVIVYIG
                     EPISFEEHFKEKLSNDDHERISQEILEVIKQNYFKYSK"
     gene            5376..6215
                     /locus_tag="JAM15_17730"
     CDS             5376..6215
                     /locus_tag="JAM15_17730"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HAT6800085.1"
                     /translation="MNIKIAKNAGFCFGVKRAMKMAWDEVEKNDSGIYALGPLIHNKQ
                     AVAKYEEKGLKTVNEIDTIPNHENMIIRSHGVPENIYNEAKDKKLKIVDTTCPFVKKI
                     HTVVSEYHNKGYEIIVIGDMKHPEVIGINGWCENSAIIIKTLEQMENMEFDNSKKYCL
                     VAQTTINPELYISIVNKLSDKLEEIVFNDTICSATKTRQESAKELAKEVDCMIVIGGK
                     HSSNTQKLVKVCEDLVPTFAIETKDELDVNTLKKYKNLGITAGASTPNWIIEEVVTFL
                     ENL"
     gene            6460..7614
                     /locus_tag="JAM15_17735"
     CDS             6460..7614
                     /locus_tag="JAM15_17735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800086.1"
                     /translation="MEMLISASEEAFLHVGSMIGFFILLFGYINYKTSGNFTNIISKN
                     RKFQPLIGALIGAIPGCGGSLAIMPLYINGKLSFGAIIASLIASMGDAAFVLISSNIK
                     MYFFVTIVSTITGIITGQLVDYFKLEEKLGLKNRRKSDKYDISKNNPKENKEQHNHDE
                     IILDTLAKSHGNTNRLAFIITHGKGYKFYIGIIVIGFIFMSLAHSGLNLPIIEKLHSL
                     EEVIAVIGILFSIIYMWCFKKVFKNSNQKEEENKKISLREMLIHSVGEISFVITWIFI
                     AYLIYDLIILILGGDEYLVKLVLSTGVISVFIGAGLGLIPGCGIQIVLMSFYLKGTIP
                     LGAVIANSISQDGDALFPLLAMDKKSSLWAMIITTIPAILVGMIVYAFLG"
BASE COUNT         3330 a          746 c         1360 g         2653 t
ORIGIN      
        1 tttataaaaa atataattta atcatttttg aggatattat tatgttagat gcatttataa
       61 caattgtttc ttctattata gaaatatggt catgtaaaaa agtttttgat tatacgagtc
      121 agacaaagac cgacttaaaa aaactaaata tgtattttct cttttctgtt tttcttatta
      181 tttcttcttt atatataaat ataggagcta atagtagaat cttgatatgt atatttgtaa
      241 tgttcgtttt ctataagtct aactataagg ttaatatata taaatgtctg gtaatctcat
      301 ttttttattg gttaatatta ataggtataa atggattaag tatgttatta gtagcaacag
      361 taagcaattt ggataatatg aatgttttac ttagtggcag tttatataga tatgaagcaa
      421 tattcttggg aaagctaatg ttaggtatat tactttatgt ttataaggct tcttttaaaa
      481 attttaaaat aagtaaaaaa gagatataca tatgtattcc tatgatagca aatttattgt
      541 cattttttgt actttatgat tatattatta atcttgtaaa aatctctcct gaaagaagaa
      601 ctgctttttt agtaatagtt ttactattaa tattatctaa catttcaatc tttgtattaa
      661 tacatataat acttaagatt aaaattagga aaataagata aattttaata cgattcattt
      721 aaattaaaag ttaataatta cttttttatg tataatttta catgaatttc tataaaagtt
      781 attttattaa agatagatat acttatatat gcggatatga ttaaaaaaag tctttttaac
      841 tttaaaaatt aatgttaaaa aataaactta tacactaata ttaataataa ttatttaaat
      901 atcttaagta aatcagtctt acatatattt ccgatagatt atattgataa aaaacactaa
      961 aattaaatta ataaaagtac ttggagggat ggaaatgaaa gaggaaaatt ttattaatgt
     1021 tgaatacgag gataaacgtt tttcaattaa tagtaaagaa gttttgtaca tagaaaagca
     1081 agagtatgaa gtaaagattt atactgaaag tggtaattat gaagttggag aaaatgctcc
     1141 ttgtataaga aaactattga aagaagaaaa ttttttcaaa tgcagtaata gttatattgt
     1201 aaatctagac aagtgtgaat tttatctcag caataattgt atttttgtga ataataattt
     1261 tataagaatt ttaggttcag aaagaaaaaa gaaattaaaa aagaaattag aaaaattata
     1321 tgattatgaa gattaatatt gagaggctgt attttataca gcctctttat ttattgattg
     1381 tattattaat aaattttaaa ttatgataaa atataaaaca agtaacttat ttcagaaaaa
     1441 aatacttttt aaaagaaagg gacgagatat gggagattat aataaaatgc ttgaattaaa
     1501 gaataactta ggtatcagtg aaagaaagtt aaaatatcct tgtatctata aacatttcaa
     1561 agggaaatat tatgctacaa tgggtcttag caaggctatt gatgatatag aaaacatatg
     1621 tgaaatatat ggtaaagaaa atttaatcca aaacagaaat aaatataaat tagttattag
     1681 acatactgaa agagaagaag atatctatgt ttatagggat tcagatggaa acttttatca
     1741 taaaaaagaa gaagatacta atgatttagt tttatacaag accttatatg atgatacagg
     1801 aatatttgca agacctttgg atatgttttt agaaaaagta gatacagata agtatgtcaa
     1861 ttcaattcaa gaatacagat ttgaagaagt atataaataa tataagagaa atatgtttat
     1921 aaatttagaa aaattcttta acagtacaat aatttgcaga aatacaaatg agatttattg
     1981 taaataatat gttagattag attataaaat agaaacaaag taaagtatta tatgatataa
     2041 ttaagttttg agaagtgata atttatattt aataaaaaat aggcatatat taggaggaca
     2101 tatgggaaat actttttata tagtaagaca tggacaaacg gattggaata tattgggaaa
     2161 aacacaaggt catggtaatt ctgaccttac gcctcaaggt atagaacagg caaaagaact
     2221 ttctgaagat attggcaagt attcaattga ttatattttt agtagcgacc ttgggagagc
     2281 aatgcaaaca gctcaaattt taggagataa gctcaatatt gaagttcaaa aaactgaggc
     2341 acttagagaa atgggattcg gagtttggga aggcctttta ataaaagaaa ttcaaaaaga
     2401 ttattcagat atatatgcaa catggagaaa tgaaccacac ttagtaaata taccagaagg
     2461 cgaaactctt aagattataa aggaaagagt agatgctttt ataaaggaac taaatgaaaa
     2521 atatgataat aaaaatataa ttcttgttac acattcaatt acattgaggg ttatgttgtt
     2581 gtcgttttta gaatcaggta tggaaaatat atatagaatt aagcaagata atactgcttt
     2641 aaatatagta gaatttaaag attatggacc tgttatagta aaaatgaatg atacaagtca
     2701 tataaaaaat catgtaaaga taaataattc tgcactggag taggaatcaa ttataaggag
     2761 aaatttatga gtaaagttat agtagttggt ggaggagctt ctggaatgat ggcagctttg
     2821 tcagcttcaa aaaacaataa tgaagtaata ttagttgaga gaaatggaga attaggaaga
     2881 aaacttaggg caactggtgg cggtagatgc aattttacca ataatagaga gatagaagat
     2941 ttttttgata aagttgtcag taataaaaaa tttctctata gtagtttcta tacatttaca
     3001 aataaagacc ttatttcgta ttttgaaagt agaaatttgg aatataagat tgaagaagaa
     3061 aatgaccaca aagtatacac taaaaatgat aaatctatag aagtaataga agtattaaat
     3121 aaagatttac tcaatcacaa tgtaaagata atgtataata aaaaagttat agatattata
     3181 actgaagaaa ttgctctaaa agatgattct aataaggaca agtcaaagta tctaataaaa
     3241 gggattattt tagataatgg agataaaata ctaggagaca aggttattat atcaactgga
     3301 ggagtgagtt attcaaagac gggttcagat ggttcaatgt ataagattct taaaaagcat
     3361 ggacatacat taaacaaact atatcctgct ttagttccac ttacaataga ggaaaaatgg
     3421 attaaagatt tacaaggaat atccatgaag aatgtggaaa tatcttgtaa gattaagaaa
     3481 aggaaaatat caaaatctgg agacatgcta tttgcccatt ttgggataac aggaccttgt
     3541 gttcttataa tgtcttctta tattaacaag attattgaaa aggaaaaggt agaattaaat
     3601 atagatttct taccaaattt aagtactgat gaaatctcta gtataatcag agcatttcca
     3661 aataaaaatg ttctaaataa tcttaagcaa atactacctc aaaatttctt aaaagagatt
     3721 ttttctctat tatctttagt tgataaaaag gcaagtgatt tgtctaaggc agatgaaatt
     3781 agaattattg agtatataaa aaatatgaag ttaacttgta atgggactac aggtataaac
     3841 actggtatgg ttacttctgg tggtatttca gttaaagaaa ttaattcttc tactatggaa
     3901 tctaaattag ttaagaactt attttttaca ggtgaagtaa ttgatataga tgcagaaact
     3961 ggtggatata atttacaaat agcattttca actggatatc ttgcgggtat aagtgtataa
     4021 atataatttt ttaataatta aatatgaata aatagaggtg tatatatggg gaatttagtt
     4081 atagctgtag atggtccagc aggagctgga aaaagtacaa tagccaagat agtagcaaaa
     4141 aagctaaata taaattatat agatacaggt gctatgtaca gagcagttac ttataagtgt
     4201 ttaaaaagtg gtattgatgt caataatgaa aaagaagtta ttcaaatagc tgaaaattcg
     4261 gatatagatt ttaaagataa caatatatat ttggacaaag aagttataaa tgaagaaata
     4321 agaacaatag aagtaagcaa taatgtttct aatgtagcaa aaataaaaga agtaagacag
     4381 ttaatggttg aagttcaacg aaaaatagga atgaaaagtt cagtaatact agatggtaga
     4441 gatataggtt catatgtttt cccagatgca gattacaaat tctttttagt agctactcca
     4501 gaagaaagag gaaatagacg ctataaagaa ctttgtaata aaggatataa tactacttta
     4561 gaagaagtaa ttgaggatat aataagacga gatgaaattg attcaaatag agaatttgca
     4621 ccattggtaa aagctaatga tgcactagaa atagatacta caggaaaaac tatagaagaa
     4681 gttgtagaag aagttgtatc taaaataaat ctttagtttt ttatgcatca taatgaaaat
     4741 aaatgtagtg ttgaagggag ataaacgtga atttttatag atttgtaata aatattttta
     4801 agggtttttc taaaatattt tttaaatatg aagttatagg tgcagagaat attccagata
     4861 gaggaaatat agtaatagca tcaaatcata aatcgaatct tgaccctata ttcttggctg
     4921 ctgccataga aaatagagaa atagctgcaa ttgcaaagaa agaattgttt aaagtaaagc
     4981 cattgggatt tatattaaaa aaattgcatg ttatgcctat aaatagagaa aaaccagatg
     5041 tatctacaat aaaaactatt ttaaggtcag ttagagatgg ttatgtatta ggaatatttc
     5101 cagaaggtac tagaataaaa ggagattctt ttggtaaggc taaggcaggt ctttctgtat
     5161 ttacaataaa aagtaaatct aaagttgttc cagtatcaat aatatctaaa tataaacttt
     5221 ttagtaaagt aattgtatat attggagaac caatatcatt tgaagaacat tttaaggaaa
     5281 aattgagtaa tgatgaccat gaaaggatat cacaagagat tttagaagtg ataaaacaaa
     5341 attactttaa atattcaaaa taagggggta aagttatgaa cataaaaata gcaaaaaatg
     5401 ctggcttttg ttttggagta aaaagagcaa tgaaaatggc atgggatgaa gttgaaaaaa
     5461 atgattctgg catatatgct ttaggtcctc ttattcataa caagcaagca gtagcaaaat
     5521 atgaagaaaa aggtcttaag actgtgaatg aaattgatac aataccaaat catgaaaata
     5581 tgataataag gtctcatgga gttcctgaaa atatatataa tgaagccaaa gataaaaaat
     5641 taaaaattgt ggatactaca tgtccatttg taaagaaaat acatacagta gtaagtgaat
     5701 atcataataa aggctatgaa ataatagtta ttggagatat gaagcatcca gaagttatag
     5761 gtataaatgg atggtgtgaa aattcagcta taataataaa gaccttagaa caaatggaaa
     5821 atatggaatt tgataactcc aaaaaatatt gtcttgttgc acagactaca ataaatccag
     5881 agttgtatat aagtatagtt aataaactat cagataaatt agaagaaata gtatttaatg
     5941 atacaatttg ttcagctaca aaaacaagac aagaatcagc taaagagtta gctaaagaag
     6001 ttgattgtat gatagttata ggaggtaaac acagttcaaa tactcaaaag ttagtaaagg
     6061 tttgtgaaga cttagtacca acttttgcaa tagagactaa agatgaattg gatgtaaata
     6121 cgcttaaaaa atataaaaat ttgggtatta cagcaggggc atctacacct aattggataa
     6181 tagaagaagt tgtaacattc cttgaaaatt tataatttga taggtaataa aaataggtgg
     6241 acattgttat aatttatcat aatatccacc tttgatttca tattacatgt ggtaaataga
     6301 taacctaata tcaaaaagtg tgtatcttaa gatgaaaaac taagagtata agatgcgcac
     6361 tttttaatat tagaaattca aaagaaatat tgatattgat tatcaataga aaatagaata
     6421 taatataatt gttgcaaaat tagtctagga ggtaaattaa tggaaatgtt gatatccgct
     6481 tctgaagagg cgtttttaca tgtaggttct atgattggat tttttatttt gttatttgga
     6541 tatattaatt ataaaactag tggaaatttt actaatatca tatcaaaaaa cagaaaattt
     6601 caacccttaa taggtgcttt aattggagct ataccaggtt gtggcggaag tttggcaata
     6661 atgccattgt atataaatgg aaaattaagc tttggagcaa taattgcaag tttaatagct
     6721 agtatgggag atgcagcatt tgtacttatt tcatcaaata ttaaaatgta tttttttgtc
     6781 actatagtta gtacaattac aggaataata acgggacaat tagtggatta ctttaaacta
     6841 gaagaaaaat tagggttaaa aaaccgtaga aaatcagata aatatgatat aagtaaaaat
     6901 aaccctaaag aaaataaaga acaacataat catgatgaaa taattttaga cactctagct
     6961 aaatctcatg gaaatacaaa tagacttgca tttataataa cacatggaaa gggatataaa
     7021 ttttatatag gaattatagt aatcggtttt atatttatgt cacttgctca ctctggactt
     7081 aatcttccta taattgagaa gttacattca ttggaagaag taatagcagt gattggaata
     7141 ttattttcaa taatttatat gtggtgtttt aaaaaggtat ttaaaaattc taatcaaaaa
     7201 gaggaagaaa ataaaaagat ttctttgcga gaaatgctta tccattctgt tggagaaata
     7261 tcatttgtaa ttacatggat ttttattgca tatcttattt acgatttgat aatattaatt
     7321 ttaggtggag atgaatactt agttaaacta gtattatcaa caggtgtaat aagtgtattt
     7381 ataggtgcag gtcttggact tattccaggt tgtgggatac aaattgtgct tatgtcattt
     7441 tatttgaagg gaactatacc acttggtgca gtgatagcca actctatttc tcaagatgga
     7501 gatgcacttt tcccactttt agcaatggat aaaaaatctt ctttatgggc tatgattatt
     7561 actactatac cagcaatact tgtaggtatg atagtttatg catttttagg ttaaatataa
     7621 ttatgaataa agaagtatta aaaaaataat aaagcacata aatttattta taagaatagt
     7681 gaagattaaa tataaaaata aaaaattcaa tatgaattaa attattgctt aaatattaat
     7741 gagaacatgg gagataatat tattcctcat gttctctcta tttaattaaa ggaattatgg
     7801 aacaaatttc aagtgatact ttctatcaaa actcatatat aatatatatt aataaattaa
     7861 actataatac gtaatacagt cagtatattg atataaaaaa cttaggagga gttgtaaaaa
     7921 tgggtaattt aaaaagacag tgtgatgttt caagtggaag agaaaaagct gacattgtac
     7981 taaaaaatgg gacaatcata aatgtattta cagaagagtt aataacagga gatgtagcaa
     8041 tagtaggaga cactatcgtt ggcattggcg attacaaggg caatgtaga
//
LOCUS       DACTZW010000128         8030 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.130, whole genome shotgun sequence.
ACCESSION   DACTZW010000128 DACTZW010000000
VERSION     DACTZW010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8030
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.130"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            898..1509
                     /locus_tag="JAM15_17740"
     CDS             898..1509
                     /locus_tag="JAM15_17740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAT6800087.1"
                     /translation="MSGYSIVNLSNMLEELEEEEVKKILSSFSCPLNKDVEEFLKNKA
                     IEFSKQGLASTHLVLTSYKGKPVIIGYFSLANKYFTIKRKTLSNSLARKIVKFGQYNE
                     ELRRYIIGAPLIGQIGKNYSNNYNKLIKGDELLKIACDKIKAVQLDMGGKIVYLECED
                     KPKLIEFYKDNGFVDFGKRSLDKDETDSLDGDYLVQMLKYLKK"
     gene            1586..1843
                     /locus_tag="JAM15_17745"
     CDS             1586..1843
                     /locus_tag="JAM15_17745"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800088.1"
                     /translation="MNDYKEKTEPKLNILVQPKVDILCSNNSTMTGVDTSIDIKLSLD
                     NRVIGNLTNEDVKYEIITCFNKCLEGINRKIGSKEVIDKLK"
     gene            1880..2305
                     /locus_tag="JAM15_17750"
     CDS             1880..2305
                     /locus_tag="JAM15_17750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAT6800089.1"
                     /translation="MAKYEYWITEEGLIKIEGWARDGLTDEQIAFNIGINVKTLYDWK
                     KKYSNICNALKKGKEVIDRQVENALLKRALGYEYDEVTYEEGQETKRVTKHVVPDTTA
                     QIFWLKNRKPAEWRDKRDIEHSGNLGDITIKVGDEEYGD"
     gene            2295..3536
                     /locus_tag="JAM15_17755"
     CDS             2295..3536
                     /locus_tag="JAM15_17755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HAT6800090.1"
                     /translation="MAINLEINPDVFNPIYLKHQLNNNNRYQIYFGGSSSGKSFSLAQ
                     RTVLDVFKGNRNYLIVRNVQSTLKRSCLNEITKAISNFKLNEYFQVNKTDMIITCKLN
                     NKQILFCGLDDVEKVKSITPIDGVITDIWVEEATETDYKAVKQLDKRLRGKSKVVKRL
                     TLSFNPILKDHWLYTEYFDIWEDDKQYVEKDNVSILKTTYKDNKFLAEDDIKALENES
                     DKYYYEVYTLGNWGVLGAVIFKNWRVEDFSDIENTFDNFRHGIDWGFADDPFAYVKSH
                     YDRMRRKLYICDEIEAVGLLNREAAPLVSKKANRDLVICDNASPKDIAEFSDLRINAV
                     SARKGAGSIEYGIKFLQGLEIIIHPRCQNFKNEINKYKYKEDKNGNILPIAVDKDNHL
                     IDALRYSLENDMEYGGISFLK"
     gene            3541..4992
                     /locus_tag="JAM15_17760"
     CDS             3541..4992
                     /locus_tag="JAM15_17760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAT6800091.1"
                     /translation="MLNIYISETDLIKAQLNKESTFNLINVIEHYILKHKPEKYQEGE
                     SYYYGNADIKNKRRYYILDGAKVVDFTKVNNKAVNNYHKLLVDQKVGYSVGNPIVFNA
                     DDDNFTKLLNELLGEEFDDTITELYLNASNKGIEWLHPYIDRKGEFKYVIIPAEEAIP
                     VWDNKRQKELVAFIRFYYIEDIDGNKIKRVEYYTENDVTYFIERGNSFVQELLYNEYG
                     TLTDVKEGHFKVNNKEQGWGKVPFIPFKNNEKSVSDLTFYKSLIDIYDNNISTLADNL
                     DEVQEAIYILKEYGGTDLVEFANNVRYYKAIKVGANGGVDKLEINIPVEAKKELLDRL
                     EKNIIIFGQGVNPESQNTGDKSGVALKFLYSLLDLKCSKTEKKFKKAIRELLWFVCEY
                     LKISSSKSYDYKSVQITFNHSMIINESEKIDMASKSTGIISDETIVSNHPWVEDVNDE
                     LKRLKKQKEESIKEYEDAFPTKKKTEEGEPLDE"
     gene            4985..6433
                     /locus_tag="JAM15_17765"
     CDS             4985..6433
                     /locus_tag="JAM15_17765"
                     /inference="COORDINATES: protein motif:HMM:TIGR01641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HAT6800092.1"
                     /translation="MNNIDYWIKTFNQLEEDVHNKGDTFNKELEKQYDIVLYNILREI
                     NNWYIKFAKDNKINMQEAEKLLNLRELAELKLSLEEYIKYGEENVISQKWMKELESAV
                     KRVRISRLEALELKTRHQIEVLYSKEYEDVNTLIADTYQDSYYHTTFETQKGIGIGLM
                     IAMLSMNNINKIVSSPWTTDGITFGNRIWNKHRPRLMSELNKGLKETLINGVSPENLT
                     NKINKNFNTSKEEAKLLVKSELAFFSSLSQRDCFNSLGVETYEIVSASDSRVCEKRCS
                     PLDGKVIEMKYYEIGITAPPFHPRCRCVVVPYFDGEESYRDAREEDGETYYIPSNMKY
                     NEWYSKYVKDSSSSGAISRKRLKDLEIYLREEKHANLYYEEIRKRTSDIKAIARNTGY
                     SEKVIQDIKNHVFMNKYNLYGGYKSFDPSYDMAISWQRLIEGKDIKKCDIILLKHERL
                     EKFLMDRYNYDYKKAHGLVVRKYDYEKALREG"
     gene            6750..6944
                     /locus_tag="JAM15_17770"
     CDS             6750..6944
                     /locus_tag="JAM15_17770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800093.1"
                     /translation="MCILTQVIVVVCVVQIVINCIANLNVSILCNKLKKENKANIDEV
                     SDEILKKVKEELNKSLEKSL"
     gene            6987..7550
                     /locus_tag="JAM15_17775"
     CDS             6987..7550
                     /locus_tag="JAM15_17775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="scaffolding protein"
                     /protein_id="HAT6800094.1"
                     /translation="MDWIKELLEGIKIEDNKIDVASLQKSIEKKIKETTVTQEDYVNL
                     ETQLNTANETIKKFEGGMTKEDVENLKTTYETDKKTLEETYKKEIEEKDFNYWLGDAF
                     KSVKCRDEIALKAHLDMEALRNSKDRQKAFEEQINPLKQDKDYLFNATLEGEEPKIDT
                     ITPGQEPKINDFGFNFTGVRPHENNNK"
     gene            7562..>8030
                     /locus_tag="JAM15_17780"
     CDS             7562..>8030
                     /locus_tag="JAM15_17780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HAT6800095.1"
                     /translation="MAALNYAKEYSNVLAQAYPYTLNFGDLYATENNGRYRWTGSKTI
                     EIPTISTTGRVDSNRDTIAVAQRNYDNAWEPKVLTNQRKWSTLVHPADINQTNYVASI
                     GNITKVYNEEQKFPEMDAYCISKIYADWTALGNTADTTVLTTTNVLEVFDKLME"
BASE COUNT         3339 a          815 c         1483 g         2393 t
ORIGIN      
        1 aaaaattccc actttattcc ctactttctc cccattttga ttaaaaaagc atgagataat
       61 agtattgtgg aaataaagat ttccctctca aaactaaata attgctaggt tagtttaaag
      121 ggctaatcta gcaatatgaa cagactaggc agggcgtgag gatgctgtta gttcaattct
      181 aactatgttc aaatattaat ctaacggata cactaaaaag tagaaaaatt gagggcaaaa
      241 ttttatattt tgtatcttaa ttcagaagtc taaaaaatcg ggtggggctt ggtaacctca
      301 ctcaccatgc aagtactggt ttagtctagg ttcgattcct agaacttgcg acataatatg
      361 tatctcccta ttaaaaagac taagtttggg gtaaacttag ccttttaatt tttaaaaaga
      421 aaaagaaatt tttattgtca taatactatt tgtttaggta tattataatg tgcatactta
      481 aaattaaata cttagcaagt atttgaatta atatacataa aatatatgac ataatttttt
      541 tatagtgtaa gttatttaaa ttaatacaaa taacagtaat tttattatat aaaatgtaca
      601 tattgtgaat aataataata aaatcatgta caaaatgcca actgataatt cctcgaaatg
      661 tattgcacat ttgacgtaac gtcagtataa ttaaattata atagtgaagt ggaaggtggt
      721 acttatggct acaaaaagta ttttaaaaaa tgtagatgta agaaaaaagg catttggaag
      781 aaatctagta tcagctctag aaaatgctaa aaataaacaa gaaaaagaag ttgtattaag
      841 taaaaaatgt tcagaagtac caaaagataa aataaaggat atattcagga gattttaatg
      901 agtggctatt caattgtgaa cttaagtaat atgctagaag agctggagga agaagaagtt
      961 aaaaagattc tctccagttt ttcttgtcct cttaataaag atgtagaaga atttttaaaa
     1021 aacaaagcta ttgaattttc taaacagggt ttagctagta cacatttagt attaacttct
     1081 tataaaggca agcctgttat aattgggtat ttttctttag ctaataagta ttttacgata
     1141 aaaagaaaaa cattatcaaa ctctttagct aggaaaatag tgaagtttgg acaatacaat
     1201 gaagaactaa gaagatatat tattggagca cctttgatag ggcaaatagg aaagaattat
     1261 tcaaataatt ataataaatt aatcaagggc gatgaacttc taaaaattgc atgtgacaaa
     1321 ataaaagcag tacagttaga tatgggtggg aaaatagtat atcttgaatg tgaagacaaa
     1381 cctaaattaa ttgaatttta taaggataat ggatttgtag attttggtaa aagaagtctt
     1441 gataaagatg aaacagattc attggatggg gactatctag ttcaaatgtt aaaatatcta
     1501 aaaaaataaa agtacataaa atctaaaatg actatcttta tagatggtct ttttttatac
     1561 aataaattaa gaaggagaat aaattatgaa tgattataaa gaaaaaactg aaccaaaatt
     1621 aaatatttta gtccagccta aagttgatat cttatgttct aataactcta ctatgactgg
     1681 agtagacact tcaattgata taaaactttc tttagataat agagttattg gcaatttaac
     1741 taatgaagat gtgaaatatg aaataataac atgctttaat aaatgtttag aggggattaa
     1801 tagaaaaatt ggaagcaaag aagtaatcga taaattgaaa taatctttat tcccaaaacg
     1861 acaaaaacga ggtggtgatg tggcaaaata tgaatactgg ataacagaag aaggattaat
     1921 taagattgaa ggatgggcaa gagatggttt aacagatgaa cagatagcat ttaatattgg
     1981 aataaatgtc aaaacactat atgactggaa aaagaagtat agtaatattt gtaatgcctt
     2041 aaaaaaggga aaagaagtaa ttgacaggca ggttgaaaat gctttgctaa aaagagcatt
     2101 aggttatgaa tatgatgagg taacatatga agaaggtcaa gaaactaaaa gagtaactaa
     2161 acatgtggta ccagatacta cagcacagat attctggtta aaaaatagaa aaccagctga
     2221 atggagggat aaaagagata ttgaacatag tggtaatcta ggagatatta caataaaggt
     2281 aggtgatgag gaatatggcg attaatttag aaattaatcc agatgtattt aatccaatat
     2341 atttgaagca tcaacttaat aataacaata ggtatcagat ttactttggt ggttcatcat
     2401 cgggtaaatc tttttcttta gctcaaagaa cagtattaga tgtatttaag gggaatagga
     2461 attatttaat tgttagaaat gttcaaagca ctctaaagag gtcttgttta aatgagataa
     2521 caaaggctat tagtaatttt aagttaaatg agtattttca agtaaataaa accgacatga
     2581 taataacttg taaactaaat aataaacaga tattattttg tggcttagat gatgttgaga
     2641 aagttaaatc aataactcca atagatggtg taataactga tatatgggta gaagaagcaa
     2701 cagagacaga ttataaagcc gtcaaacaac ttgataagag acttagagga aagtctaaag
     2761 tagtaaaaag actaacatta agcttcaatc caatacttaa agaccattgg ctatatacag
     2821 agtattttga tatatgggaa gatgataaac agtatgtaga aaaagataat gtaagtattc
     2881 taaaaactac atataaagat aataaattct tggcagaaga tgatataaaa gctttagaaa
     2941 atgaaagtga taaatattat tatgaagttt acactcttgg aaattggggc gtacttggtg
     3001 ctgtcatatt taagaattgg agagttgaag atttctcaga tattgaaaat acatttgata
     3061 actttagaca tggaattgac tggggatttg ctgatgaccc atttgcgtat gtaaaatcac
     3121 attatgatag gatgagaaga aaactatata tatgtgatga aatagaagca gttggattat
     3181 taaatagaga agctgcacct ttagttagta aaaaagcaaa tagagattta gttatttgcg
     3241 ataatgcaag tccaaaagat atagctgaat ttagtgactt aagaatcaat gcagtttcag
     3301 caagaaaagg agctggttct attgagtatg gtatcaagtt tttacaaggt cttgaaatta
     3361 taatacatcc aagatgccaa aactttaaaa atgaaataaa taagtataaa tataaagagg
     3421 ataagaatgg aaatatctta cctattgcag tagacaaaga taaccattta atagatgcac
     3481 taagatatag cttagaaaat gacatggagt atggaggaat aagcttcttg aagtaaggag
     3541 gtgttaaata tttatataag tgaaacggat ttaataaaag ctcaactaaa caaagagagt
     3601 acttttaatc ttattaatgt tatagagcat tatattttaa aacataaacc agagaagtac
     3661 caagaaggag aatcatacta ttatggtaat gctgatataa aaaataaaag aagatattat
     3721 attttagatg gtgctaaggt tgtagatttt actaaggtta ataataaagc agttaataac
     3781 tatcataagt tattagttga ccagaaagta ggctacagtg ttggaaatcc aatagttttt
     3841 aatgcagatg atgacaattt cactaagctt ttaaatgaac tgctagggga agaatttgat
     3901 gatacaataa cggaactcta tctcaatgct agtaacaaag gtattgaatg gctacatcca
     3961 tatattgaca gaaaaggtga gtttaaatat gtaataatac ctgctgagga agctattcct
     4021 gtgtgggaca acaaaagaca aaaggaatta gttgcattta ttagattcta ctacattgaa
     4081 gatatagatg gtaacaagat aaaaagagtt gaatattata cagaaaatga tgtaacttac
     4141 tttattgaaa gaggtaatag ctttgttcaa gagctattat ataatgagta tggaacatta
     4201 acagatgtaa aagaaggaca tttcaaagta aataacaaag agcaaggatg gggtaaagtt
     4261 ccatttatac catttaaaaa caacgagaaa agcgtgtctg atttaacttt ttacaagtct
     4321 ttaattgata tatatgataa taacatttct actcttgcgg ataacctaga tgaagtgcaa
     4381 gaagcgatat acatactaaa agagtatggg ggtactgatt tagtagagtt tgcaaataat
     4441 gtaagatatt ataaagccat taaagtagga gccaatggtg gagttgataa gttagagata
     4501 aatataccag ttgaggctaa gaaggagctt cttgacagat tagaaaagaa tataattatt
     4561 tttggtcaag gggttaatcc cgaaagtcaa aacacaggtg acaaatcggg tgtagcactt
     4621 aaatttttat attcactact tgatttaaaa tgttctaaga ctgaaaagaa gtttaaaaaa
     4681 gcaattagag agcttttatg gtttgtatgt gagtatttaa agataagtag cagtaaaagc
     4741 tatgattata agtcagttca aataacattt aatcattcta tgataataaa tgagtctgaa
     4801 aaaatagata tggcttctaa atcaactgga attatatcag atgaaactat tgtcagtaat
     4861 catccttggg ttgaagatgt taatgatgaa ttaaagcgac ttaaaaaaca gaaagaagaa
     4921 agtataaaag aatatgaaga tgcttttccg actaaaaaga aaactgaaga aggtgaacct
     4981 ttagatgaat aatatagatt actggataaa gacatttaat cagttagaag aagatgttca
     5041 taataaaggt gataccttta acaaggaatt agaaaagcaa tatgatatag tactttataa
     5101 tattcttaga gaaataaata attggtatat aaaatttgct aaggataata aaataaatat
     5161 gcaagaagct gaaaagttat taaatctaag agaattagct gaacttaaat tatcattaga
     5221 agaatatatc aagtatggag aagaaaatgt aattagtcaa aagtggatga aagaactaga
     5281 aagtgcagtt aaaagagttc gtataagtag actagaagca ttagagttaa aaacaaggca
     5341 tcaaattgag gtattatact caaaagagta tgaggatgta aatacgctta tagcagacac
     5401 ttatcaagat agctattatc atactacatt tgaaactcaa aaaggtattg gaattggatt
     5461 aatgatagcc atgcttagca tgaataatat taacaaaata gttagtagtc cttggaccac
     5521 tgatggaata acatttggta atagaatttg gaataagcat agaccaaggt taatgagtga
     5581 acttaataaa ggattaaaag aaactttaat taatggagta tctcctgaaa acttaacgaa
     5641 taaaattaat aaaaatttta atacaagcaa agaagaagct aagttattag taaaatctga
     5701 gcttgccttt tttagttcat taagtcaaag ggattgtttt aatagtctag gtgttgagac
     5761 atatgaaata gtaagtgcat cagatagtag ggtttgtgag aaaaggtgta gccctcttga
     5821 tggtaaagta attgagatga aatattatga aataggaatt acagctccac catttcatcc
     5881 tagatgtaga tgtgtagtag taccatattt tgatggtgaa gaaagttata gggatgcaag
     5941 agaagaagat ggcgaaactt attatatacc atcaaatatg aagtataatg agtggtattc
     6001 gaagtatgta aaagatagtt cctcaagtgg agcaataagc agaaaaagac taaaggacct
     6061 agaaatatat ctaagagaag aaaaacatgc taatttatat tatgaagaaa taagaaaaag
     6121 aactagtgat attaaagcga tagctagaaa tacaggctat agcgaaaagg taatacaaga
     6181 tataaaaaat catgtgttta tgaataaata taatttatat ggtggatata aaagttttga
     6241 ccctagttat gatatggcta tttcttggca aagattaata gagggaaaag atataaaaaa
     6301 atgtgatata atattattaa agcatgagag attagaaaag tttcttatgg atagatataa
     6361 ttatgattat aagaaagctc atggtttggt tgttagaaag tatgattatg aaaaagcttt
     6421 gagggaggga taaacatagt acttataaag aaaaattata taaaagatga taaagtatct
     6481 tatttttatc aaccagaaga agatggagag tttggagaag ttatacttta tactaaagat
     6541 aaatcttttg atatagtaaa aagagcagaa agagacagtg aagggaatca tttttatatg
     6601 tctcatgttt actgtatgat acgtaaattt atagaagaaa ataattatcc agatgagaaa
     6661 acatcttatt ggtattagaa agcacttgct aagtaataaa ttagtaggtg cttttattat
     6721 gtaaaaattt aaaaaggtag gtgattttaa tgtgtatatt aactcaagtc atagttgtag
     6781 tttgtgtagt acaaatcgtt attaattgta ttgctaatct taatgtaagt attctttgca
     6841 ataaattaaa aaaagaaaat aaagctaata tagacgaagt ttctgatgaa attttaaaga
     6901 aggtaaaaga agagctaaat aaatcattag aaaaaagtct ttaagaggct tttttatttt
     6961 gtaaaaaatg aaaggagata ttagaaatgg attggataaa agaattactg gaaggaataa
     7021 aaatcgagga taacaaaatt gatgtagctt ctcttcaaaa atctatagaa aagaaaataa
     7081 aagagactac agttactcaa gaagattatg taaatcttga aacacagctt aatacagcta
     7141 atgaaactat taaaaagttt gaaggaggta tgacaaaaga agatgtagag aatctaaaaa
     7201 caacttatga aactgataag aaaactttgg aagaaaccta caaaaaagaa attgaagaaa
     7261 aagactttaa ttactggtta ggtgatgctt ttaagtctgt taaatgtagg gatgaaatag
     7321 cattaaaagc tcatttagac atggaagcac taagaaatag taaagataga caaaaagctt
     7381 ttgaagagca aataaaccct ttgaaacagg ataaagatta tttgtttaat gcaacactag
     7441 aaggtgaaga gcctaaaata gatactataa caccagggca agagcctaag ataaatgatt
     7501 ttggttttaa ttttactggg gtaagacctc atgaaaataa taataaatag gaggaaataa
     7561 aatggcagca ctaaattatg caaaagaata ttcaaatgtt ttagcacaag catatcctta
     7621 tactttaaac tttggggatt tatatgctac agaaaataat ggaagatata gatggactgg
     7681 ttctaaaaca atagagatac caactatatc tacaactgga agggtggatt caaacagaga
     7741 tacaatagca gtagctcaaa gaaactatga taatgcttgg gaacctaagg tattaactaa
     7801 tcaaaggaaa tggtcaacat tagttcatcc agctgatata aaccaaacta attatgtggc
     7861 ttcaataggc aatataacaa aagtatataa tgaggaacaa aagtttccag agatggatgc
     7921 ttactgtata tctaaaatat atgctgattg gaccgcatta ggtaacacag cagatacaac
     7981 tgttcttaca acaacaaacg tattagaagt atttgataag ttaatggaaa
//
LOCUS       DACTZW010000129         7888 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.131, whole genome shotgun sequence.
ACCESSION   DACTZW010000129 DACTZW010000000
VERSION     DACTZW010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7888
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.131"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(381..2660)
                     /locus_tag="JAM15_17785"
     CDS             complement(381..2660)
                     /locus_tag="JAM15_17785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HAT6800096.1"
                     /translation="MLSDAKNNRYGLSIIAVISILVITISCLIYGSRLNKTLGEETNQ
                     YLSEIANQSVNVLKKQINGDIKLLESISIFIEGEESFEVDNILSILKRQAINSSFKRM
                     GVILPNGTAYTTDGYIEDFSKRDYFLKSMQGEVVITGKLKDVIEDDKNTNSNINVYSV
                     PIYKDNEVKGVIFATHSTKLYEKILSVPTFNGKGYSYIARSNGNIVLNPSSKNANSTK
                     ENLFSYIGRSDSISKSSINNMKSNIKNFKSGSLSYSMFGKGYYLSYAPIGINDWYLFS
                     EVPKTAISEKSYAIIKLTLSACVVLIIIFTALTIYILFIHKKSKEKLEEFAFKDNVTG
                     IGNSNKFNLEGGKFLSSHEKKNLVLIYFDIDKFKLVNDRFGYEEGDRVLKEIAEIIKN
                     VFKEQSVFSRISNDNFAIIFEKKNNRESIIEICELIRKKLSMIKTSLGVELNLIPSIG
                     VYFVEEGETNISTCLDKAMIAKTTVKRKYLKVYEIYAENLKETLIEERDIEQEMHDAL
                     KNEQFKVYLQPKVDLSTTKIVGAEALVRWQHPKKGLISPGVFIPIFEKNGFITELDMF
                     VFAQVCKNFKRWENENFPTFPISINLSRVHLENPGFISELERITKEYEIEPNLIEIEL
                     TESAIFDNTKILFKIMQTLKSVGFKISMDDFGSGYSSLNMLKDMPIDVLKLDRQFFIT
                     VGNAKKSQIVVSSIVQMAKQLDIKVVSEGVETVEQAEFLRFIGCDMAQGFLFARPMPI
                     EEYEKLILDRYSLNRKETN"
     gene            complement(2931..4385)
                     /locus_tag="JAM15_17790"
     CDS             complement(2931..4385)
                     /locus_tag="JAM15_17790"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HAT6800097.1"
                     /translation="MKLNDIIQGLDIINVKGELNIDINNVQYNSRKVTKGTLFICIKG
                     FVSDGHKYIKDAIEKGASAFLVEEDVEIKGCTFIKVKDTRKDMAKVADNFYNHPSQKF
                     NVIGVTGTNGKTSITTILNEILTLNKNKVGLIGTIKIFDGEKDIVSNSTTPESIDLQY
                     HFNNMLDNGCDYCAMEVSSHSLALNRVDETDFKLGIFTNLTPDHLDFHKDLEDYRKAK
                     EKLFFKTTMANIINIDDEGGKKIYENIKGINVPCYTYGVDTKADFMARDIKSDSDGVS
                     YRLITPSYEEVIFIPVPGMFTVYNTLAVIAACYVLGIPKPIYKEGLRLSNGVSGRFET
                     VPNDKGISVIVDYAHTPDALENVLKTTQQFAEGKIISVFGCGGDRDTEKRPLMGAIGQ
                     KYSDLCIITSDNPRTEEPEAIIKDILEGIDKKKENYHVVVDREQAIAEAISMAKKDDV
                     VIITGKGHETYQIIGKVKHHFDDKEVANECLSKM"
     gene            4549..5418
                     /locus_tag="JAM15_17795"
     CDS             4549..5418
                     /locus_tag="JAM15_17795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAT6800098.1"
                     /translation="MDNKIGYLNDNFKIFNIRDKKDIQFEYHNHDFNKIIIFINGNVT
                     YFVDGIPYKLKPWDILFISNNEIHKPVIDSNVFYERIAIWISPEFMKKNSDATSDLEK
                     CFKIATENKCNRLRLNIHDIESIKSFIEQINISESNTEFGNEILRNALFIQLMIFLNR
                     IFLKNENMESTEDVFYDETIKKVLNYINSNIDDKLSIDSISSEFFISKYYLMRKFKSH
                     TGTSIHNYIVQKRLILAKSLITNGYLMSEVCNKCGFNDYSSFVRAFKKNYGVSPKNYI
                     NNKNPLDITLLDE"
     gene            complement(5632..7704)
                     /locus_tag="JAM15_17800"
     CDS             complement(5632..7704)
                     /locus_tag="JAM15_17800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAT6800099.1"
                     /translation="MKKVFGVLQKVGKSLMLPVALLPAAGILLGVSNALAGDALLSHF
                     PALANPTFQLIISIMESSGQIIFNNLPLIFAVGVAVGLTEGEGVAALAAIVGFLILNT
                     SMGVMAGVTEDMVDNSMYASIVGIPTIQTGVFGGIIIGIVAAYLYKKFYKIELPQYLG
                     FFAGKRFVPIVTSLVAIAIGIILSFIWPPIQEGLLSFSKNVIEANQTLAAFMEGSLER
                     LLIPFGLHHVFHNPFWYQFGEYVNKSGELVMGDQKIFFAQLKDGVNFTAGTFMTGAFP
                     FMMFGLPAAALAMVHEAKPEKKKFVAGIMASAELTSFLTGITEPIEFAFLFVAPVLFA
                     IHCLFSGLSYAIMQLLGVKIGFTFSGGLIDFLLFGVLPNRTPWYLAILVGIGFAVLYY
                     SVFRFMIRKFNLKTPGREDESETNAEVIEMSKNELASEILIALGNKDNLKSLDACITR
                     LRLVVNDINKVDKEKLKLLGAAGVMVIGNNVQAIFGPKSDSIKSDIKDIIEGKTKVES
                     TVTKNVDKNKVKKNMEVANMENALVEKIDSLTNGEILDIEEVPDSVFSSKLMGDGFAI
                     KSSDGLIYSPVDGTIGVIFPTKHAIIIKSKKSGVEILIHLGIETVNLEGNGFEVFVNV
                     GDEVKAGEKLVKMDLEYIEKNCLSTISPVVFTNLEQNQKLSIKKGITTAKEENRVSIL
                     RYDIEKIG"
BASE COUNT         2700 a         1297 c          824 g         3067 t
ORIGIN      
        1 aaaataaaag aagagtattt caaatgattt gtataaatta ttatgaaaaa ctcttttttt
       61 gatataataa aattacttac atatataaca tttaaattta taaattatct ttttattttt
      121 taaaatatgt ataacacacc tatagaaatt actattatta ctatctaaag tattttgcta
      181 taatcccata tactcttacc tcaaaaacat tcaaatggaa aaaatactac atattaataa
      241 actttgccca ataattccta aaataatatc ctaacaatga tttatgtttt tataatagta
      301 tatttttaca taaaaaagtg aacattgatt aacaaagttc acttttttat aaatttttat
      361 gttataattc acaattttat ttaatttgtt tcttttctat ttaaactata tctatctaat
      421 attaattttt catattcttc tattggcatt ggtctagcaa ataaaaatcc ttgggccata
      481 tcacaaccta taaaccttaa aaactctgct tgctctacag tttcaacacc ttctgaaaca
      541 acttttatat caagttgctt tgccatttga acaatacttg aaactacaat ttgactcttt
      601 tttgcatttc ccactgttat aaagaattgc ctatctaatt tcaatacatc aattggcata
      661 tctttaagca tatttaaaga agaataacca gaaccaaaat catccataga aattttaaat
      721 ccaacagatt tcaaagtttg cattatttta aataatattt ttgtattgtc aaatattgca
      781 ctttctgtca attcaatctc aattaaattt ggttcaattt catattcttt tgttattctt
      841 tcaagctcag aaataaaacc tggattctca agatgtactc ttgataaatt tattgatata
      901 ggaaatgtgg ggaaattttc attttcccaa cgtttaaaat ttttacaaac ttgggcaaat
      961 acaaacatat ccaattctgt tataaaacca tttttctcaa aaataggaat aaatacacct
     1021 ggacttatta gacctttttt gggatgttgc caacgtacaa gcgcttcagc acctacaatt
     1081 ttagtagttg ataaatcaac cttaggctgt aaataaactt taaattgttc attttttaaa
     1141 gcatcatgca tttcttgttc aatatcacgt tcttctatga gagtttcttt taaattttca
     1201 gcataaatct cataaacttt taaatatttt ctttttactg tagtttttgc aatcatagct
     1261 ttgtcaagac aggtagaaat atttgtttct ccctcttcaa caaaatatac acctatggat
     1321 ggaattaaat tgagttctac tcccaaactt gtttttatca ttgacaattt tttacgtata
     1381 agttcacata tttctataat tgactctcta ttatttttct tttcaaatat tatagcaaaa
     1441 ttgtcatttg aaattcttga aaatacagat tgttctttaa atacattctt aattatctct
     1501 gctatttcct ttaatactct atctccttct tcatacccaa acctatcatt tactagctta
     1561 aacttatcta tatcaaaata aattaaaact agattctttt tctcatgaga ggataaaaat
     1621 tttccccctt caagattaaa tttatttgaa ttaccaatac ctgtaacgtt atctttaaaa
     1681 gcaaattctt ctaacttttc cttactcttt ttatgtataa atagtatata aattgttaat
     1741 gccgtaaaga ttataatcaa cactacacat gctgataatg taagttttat aatagcgtat
     1801 gatttctcag atatagcagt tttaggaact tcagaaaaaa gataccaatc attgattcct
     1861 attggggcat aacttaaata atatcctttt ccaaacatac tataacttaa tgaacctgat
     1921 ttaaagtttt ttatatttga cttcatatta ttgatactag attttgatat tgaatcactt
     1981 ctgccaatgt aagaaaataa attttcttta gtagagttgg cgtttttgct gcttggattt
     2041 aaaacaatat taccattact tctagctata taagaatatc cttttccatt aaatgtaggt
     2101 acagaaagta ttttttcata caacttcgta ctatgtgtag caaatataac tcctttaacc
     2161 tcattatctt tataaattgg cacagaatat acattaatat tactattggt atttttatca
     2221 tcttctatta catcttttaa ttttcctgtt ataaccactt ctccttgcat tgattttaag
     2281 aaataatctc ttttagagaa gtcttctata taaccatctg tagtgtatgc tgtaccattt
     2341 ggtaaaataa ctcccattct tttaaatgaa ctattaatag cttgtctttt tagtatagaa
     2401 aggatattat ctacttcaaa agactcttct ccctcaataa atattgaaat tgactctagt
     2461 aactttatat ctccattaat ttgttttttt aacacattga cgctttgatt tgctatttct
     2521 gaaagatatt gattcgtttc ttcacctaat gtcttattca accttgaacc ataaatcaaa
     2581 caggaaattg taattactaa gatacttatg acagcaatta tggacaaacc atacctatta
     2641 ttttttgcat cacttaacat tatgcttcct gcctttctcg aatctatgta tgtataatca
     2701 ttatcttatg acaattattg taaacatttt ataataatac ttatttttcc atatttactg
     2761 taattataca aaattataaa ctttattaca acaataaatt aattaatata gatattaggg
     2821 tttatattat tgcattatct attttacaat catttacata taaaaaaatg taatatcaaa
     2881 gtgaaacttg atattacatt tttgttcttg tattttgttt aatttttatg ctacatttta
     2941 cttaaacact catttgcaac ttctttatca tcaaaatgat gcttaacttt acctataatt
     3001 tgataagttt catgtccctt acctgttata attacaacat catccttttt tgccatactt
     3061 atagcttctg ctatagcttg ttctctatca acaacaacat ggtaattttc ttttttcttg
     3121 tcaattcctt caagtatatc ttttattatt gcctctggtt cttcagttct tggattatca
     3181 gaagttataa tacataaatc agaatatttt tgtccaattg ctcccatcaa aggtctcttt
     3241 tcagtatctc tatctccacc acatccaaac acagaaatta tttttccttc tgcaaattgt
     3301 tgagttgtct ttagtacatt ttcaagtgca tcaggagtat gagcatagtc tacaattaca
     3361 cttatacctt tatcatttgg aactgtttca aaccttcctg atactccatt agaaagtcta
     3421 agaccttctt tatatattgg tttaggtatg ccaagtacat agcaagcagc tataactgct
     3481 aaagtattat atactgtaaa cattcctgga actggtataa atattacttc ttcatatgaa
     3541 ggtgttatta atctataaga tactccatcc gaatctgatt ttatatctct agccataaaa
     3601 tcagccttag tatcaacacc ataagtgtaa caaggtacat ttataccttt tatattttca
     3661 tatatctttt ttccaccttc atcatctatg tttattatat ttgccatagt agtcttaaaa
     3721 aataattttt cttttgcttt tctataatcc tctaaatctt tatgaaaatc taaatggtct
     3781 ggtgttaaat ttgtaaatat gcctagttta aagtctgttt catcaactct atttaatgcc
     3841 aatgaatgtg atgaaacttc catcgcacag tagtcacatc cattatccaa catattatta
     3901 aaatgatatt gtaaatctat actttctgga gttgttgaat tggaaacaat gtctttttct
     3961 ccgtcaaaaa tttttatagt tcctataagt ccaactttat tcttatttaa agttaatatc
     4021 tcatttagta tagtagttat actagttttt ccattagtac ctgtaactcc tataacgtta
     4081 aatttctgag atggatgatt ataaaaatta tcagctactt ttgccatatc ttttcttgta
     4141 tcttttacct ttataaatgt acatcctttt atttctacat cttcttcaac aagaaatgca
     4201 cttgctccct tttctatggc atcttttata tacttatgac catctgacac aaatcctttt
     4261 atacatataa ataatgtacc ttttgtaacc tttcttgaat tatattgtac attattaata
     4321 tctatattta attcaccctt gacattgatt atatccaacc cctgtataat atcatttaat
     4381 ttcataaatg ctttcctccc tttaaactct ttctgctaaa attacactac atataatatt
     4441 atattaagaa ttttttacta tgtgaatggt taaaaatgct tgaaacattg caaaaaatgc
     4501 tctataattt tctataatat aactgaggaa aggtcttcta taaaaactat ggataataaa
     4561 atcgggtact taaacgataa ctttaaaata tttaatatta gagataaaaa agatatacaa
     4621 tttgaatacc ataatcatga ttttaataag ataattatat ttataaatgg aaatgtaact
     4681 tattttgttg atggtattcc ctataaacta aagccttggg atatactctt tatcagcaat
     4741 aatgaaatcc ataaaccagt tatagattca aatgtctttt atgagagaat tgcaatatgg
     4801 attagcccag aatttatgaa aaaaaatagt gatgctacta gtgacttaga aaaatgtttt
     4861 aaaatagcta cggagaataa atgcaataga ttgcgtttaa atatacatga tattgaatct
     4921 attaagagtt ttattgagca aataaatatt tccgaatcca atactgaatt tggaaatgaa
     4981 atattgagaa atgcattatt tatacaactt atgatattct taaacagaat tttcctaaaa
     5041 aatgaaaata tggaatcaac agaagacgtt ttttatgatg aaactattaa gaaagtatta
     5101 aactatataa attcaaatat agatgataag ctttcaatag atagcatatc gtctgaattt
     5161 tttataagta agtattatct tatgagaaaa tttaaatctc atactggaac gtctatacac
     5221 aattatatag ttcaaaaaag attaatttta gcaaagtcac taataaccaa tggttacctt
     5281 atgagtgaag tttgtaataa atgtggattc aacgattatt ctagttttgt aagggcattt
     5341 aaaaaaaact acggtgtatc tcctaaaaat tatataaaca ataaaaatcc tttagatatt
     5401 actcttttag atgaatagat aatttatgta aattttattt taataaaaac ttgaagtatt
     5461 agtgtattta tcttactaat acctcaagtt ttttaatgtt ttaaaatata tcaaaatata
     5521 atgatatata tttctattac ttaaaatata tattaaataa attgcatgtt aactgaacct
     5581 atttatatat ttattaaatc tcacataact tttagttata ctatcatata gctatcctat
     5641 tttttcaata tcatatctta atatacttac tctgttctcc tcttttgctg tagttattcc
     5701 ttttttaatg cttaatttct gattttgttc taaattcgta aatactacag gacttattgt
     5761 tgatagacaa tttttttcaa tatattctaa gtccatttta actaattttt ctcctgcttt
     5821 tacttcatct cctacattca caaatacttc aaatccattt ccttctaaat ttacagtttc
     5881 tatccctaaa tgtataagta tttctactcc actttttttg gattttatta ttattgcatg
     5941 cttagttgga aatataactc caatagttcc atcaactggt gaataaatca atccatcact
     6001 agatttaatt gcaaatccat cccccatcag tttacttgaa aatacagaat ctggcacttc
     6061 ttctatatct aatatctctc catttgttaa tgaatcaatc ttttctacta aagcattttc
     6121 catattggca acttccatat tttttttcac tttattttta tcaacatttt tagtaacagt
     6181 actttcaacc tttgtttttc cctctattat atcttttata tcagacttta ttgaatccga
     6241 ttttggtcca aatatagctt gaacattgtt gccaataacc ataacacctg ctgctccaag
     6301 taatttcaat ttttctttat ctactttatt tatatcattt acaaccaatc taagtcttgt
     6361 tatacacgca tctaggctct ttaagttgtc tttatttcct aaagcaatta aaatctctga
     6421 tgctaattca ttcttagaca tttcaatgac ttcagcgtta gtttctgatt catcttctct
     6481 tcctggtgtc tttaaattaa attttcttat cataaatcta aatacactat agtataatac
     6541 tgcaaaacca atacctacca agatagccaa gtaccatgga gttctattag gaagaacacc
     6601 aaataataag aaatctatta atcctcctga aaatgtgaat ccaattttaa ctcctaataa
     6661 ttgcataatt gcgtatgata aacctgaaaa taaacaatgt attgcaaata atactggtgc
     6721 aacaaataaa aacgcaaact ctattggctc ggttattcct gttaaaaaag aggttaattc
     6781 tgctgatgcc attatacctg ctacaaattt tttcttttct ggctttgctt catgcaccat
     6841 agcaagagct gctgctggaa gaccaaacat cataaatgga aatgcacctg tcataaaagt
     6901 acctgctgtg aaatttactc catctttaag ttgagcaaag aatatctttt ggtcacccat
     6961 tacaagctca ccagatttat ttacatattc tccaaattga taccaaaatg gattatggaa
     7021 aacatgatgc aaaccaaatg gtattaatag tctttccaaa gaaccttcca taaatgctgc
     7081 tagtgtttga tttgcttcta taacattttt tgagaaacta agtaatccct cttgtattgg
     7141 aggccaaata aaagacaata taattcctat tgctatagca actaatgaag taacgattgg
     7201 tacaaatctt ttacctgcaa aaaaacctag atactgaggt aattcaattt tataaaactt
     7261 tttataaaga taagcagcca ctatccctat aataatacca ccaaataccc ctgtttgaat
     7321 tgttggtatt ccaacaatac ttgcatacat agaattgtct accatatctt ctgtaacacc
     7381 cgccataaca cccatagatg tattgagaat taaaaaacct actatggctg ccaatgctgc
     7441 aacaccttct ccttcagtta aaccaacagc taccccaact gcaaatataa gtggtaagtt
     7501 attaaatata atttgacctg aactttccat tatacttatt ataagttgaa atgtaggatt
     7561 cgccaaagct ggaaaatgag acaacaatgc gtctcctgct aaagcattac tcacgccaag
     7621 taatatacct gctgcaggaa gtaatgcaac tggtagcatt agagattttc ctactttttg
     7681 taaaacacca aatacttttt tcatttactt ttctctcctt attattttat atttttttaa
     7741 ataaaaaaga cttaagttta taaaaagtta cattagtata cttaattcta aaattaaact
     7801 tatgttaata taaataaacc tatattaacc taatttcaga attaaaaata aactattata
     7861 atttttttat aaacataagt cttgcctg
//
LOCUS       DACTZW010000130         7700 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.132, whole genome shotgun sequence.
ACCESSION   DACTZW010000130 DACTZW010000000
VERSION     DACTZW010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7700
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.132"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            <1..687
                     /locus_tag="JAM15_17805"
     CDS             <1..687
                     /locus_tag="JAM15_17805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAT6800100.1"
                     /translation="ATTTEIKSLFVEFTKRMRDKVGAKFQTVLYKKSDADYEGVVSVE
                     NKIKDAGLLESSLIYWTTGAIAGCDINKSNTNKRYDGEFDVDVNYTQIQLEESLKSGK
                     FIFHKVGDEVHVLEDINTFVSFTDDKNDDFSSNQSVRVLDQIANDIATLFNEKYLGKV
                     PNDKAGRISFWNDVVKHHKELENIRAIEDFKTDDVSVELGNDKKTVIVSDGVKVINAM
                     SKLYMTVSVS"
     gene            708..1184
                     /locus_tag="JAM15_17810"
     CDS             708..1184
                     /locus_tag="JAM15_17810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HAT6800101.1"
                     /translation="MPKNAPMNVKDTISASLAECFVTIEGKRYNFMQAINLEAKMEKT
                     KSEVPILGKTTKGNKTTGSKITGSATFHFNTSIFRELLYRYKETGEDIYFDIQVTNED
                     PTSSVGRQTVILKDCNMDSGIITKFDADGEYLEEDMDFTCEDWELVEKFKTLIGME"
     gene            1238..1495
                     /locus_tag="JAM15_17815"
     CDS             1238..1495
                     /locus_tag="JAM15_17815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800102.1"
                     /translation="MVKIKDKYKMKDSVSFDYSNKRKIEECVGEMYRKAGLFLVDIAD
                     KLALDTIEGSSLKPITITIKLDENGITTIEKQTKYLVMEVE"
     gene            1497..1937
                     /locus_tag="JAM15_17820"
     CDS             1497..1937
                     /locus_tag="JAM15_17820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020815252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAT6800103.1"
                     /translation="MGDLNAFLSQNAIKVENRKYVASNRFINEEGKAIEWEIRALSSE
                     EDAAIRKNCPKREPILNKKGKHTGQYNTVTDYNKYYEELSIACTVFPDLNDSMLQDSY
                     RVMGANQLLKAMLTPGEYTEYVQEVLDINGFDNSFEDKVEEAKN"
     gene            1937..2131
                     /locus_tag="JAM15_17825"
     CDS             1937..2131
                     /locus_tag="JAM15_17825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015390885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800104.1"
                     /translation="MYEGDYDSNIAHYCLHKFKWKPHEYMDLPVDEKAFVAASIDIKV
                     EEEKEEAKKADKDAKRGRRR"
     gene            2203..2763
                     /locus_tag="JAM15_17830"
     CDS             2203..2763
                     /locus_tag="JAM15_17830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800105.1"
                     /translation="MKKKACFLVSIFIVICLAIVGCSNSESLESSNKDNKPKKEEKKD
                     KEVVVGEKIVSDKMEITINKVEFSYDVLPKVKESFYTHYPAESGKVYIDIAADIKNAQ
                     KQELNCSDLLTIEADYNDGYKYSSQTIVEDETTGFTYDNITSIDPLETKGVRFIIDCP
                     DEVKTSDKPVILNFTFDGNKYVYKMK"
     gene            2807..3376
                     /locus_tag="JAM15_17835"
     CDS             2807..3376
                     /locus_tag="JAM15_17835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HAT6800106.1"
                     /translation="MNDTVEYIFCSKCGVKCLKGSKFCSECGNKIDDIKMSNESITKD
                     KEYDLKGVSLQHIMQETNFIKASSIRRLKELTGIDLEDCRKILEEPYQKYYDENAEML
                     EEKRKKEDDMSKIRRAKDEKKEKEKIACCPSCGSTSLSAHKKGFGIGKAVVGASLTGG
                     IGLVAGNLGAKKVRVTCLNCGKQFWAGKK"
     gene            3452..5746
                     /locus_tag="JAM15_17840"
     CDS             3452..5746
                     /locus_tag="JAM15_17840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HAT6800107.1"
                     /translation="MATIQTSIKIFDGMTPAFRNMTTSINTTINSLERLQQRLHNPIN
                     AGNIQTSQQSLNNIENILTRIEQNTGKAGEQQRKFNEEVDKGVGSTDRLLGNVKRLAT
                     TYLGLKTLGGLGGLSDQMTSTNARLAMINDGQLSDGGLNKMIFQSAERSRASYLDTAQ
                     IVSRIGMNAGSAFSSTREIVSFAEQLNKKFIIAGASTQEMNSALLQLTQGLGSGVLRG
                     EELNAVFESAPNIIRSIADYLDVDIGKIRGMASEGMLTADIVKNSLLAAAEQTNAEFE
                     KMPYTFNQIWTSIKNNAIMIFGVIQKKIEQSMSSKGFRTFIDNLIDTLYILGAVGFDI
                     FNGFITLLSSPVFQGFANMMLVSIGIVVQGFGWLLTTVGSVVNFIAQGWSIIQPLLIT
                     SIVLWGLYKAAILAGAIVTAIQVGWTALQAFWTNLLNGSLLTNIMMSIAAAIATDALS
                     GSMILLITTITIVVTVIALVIAAVFVGIAIFNHFARTSISAIGAVAGAISVAAAFIGN
                     LFIATGNLMIDIVALIYNTLAGFAEFFANFLDDPIGSVIRAVSGMANAVLGIIRSIAS
                     AFDTVFGSNLADAVSGWQDTLQGWTDKVAGEAKIKVERMDPNKLHFDRFNYGKAWDAG
                     YKWGDKLETNIKDKFDISKIAEKAKKDLGLDDLWDKKYGLGDSIGSAGLNSPLSDAAK
                     GAKDTAGNTAKMAKTMDKSQEDLKYLRDIAEQETINRYTGVNIKIDMNNTNNISKDTD
                     VDGIVNVLTEKLNDAMVVSAEGIV"
     gene            5763..6452
                     /locus_tag="JAM15_17845"
     CDS             5763..6452
                     /locus_tag="JAM15_17845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAT6800108.1"
                     /translation="MAYDFYLDGVQLPIPPAKLEIKVTNKNKTVDLINTGEVNILKKE
                     GLSEISFEAEFTHNKLPFYRGAFRDVQFFLSKLELLKTDCKPFQFIVSREMGGKVLFN
                     TNMKVSLEEYNIVEDADNGSDTKVAIKLKQYRDYSTKKLVLAPPKNETGRPNVKIEPK
                     RVDSVNATNTKTYTVKAGDSLWSICQKQLGNGSLYKKVYELNKSMMDKANKGKNLSKY
                     TIYKGQVLKLG"
     gene            6445..>7700
                     /locus_tag="JAM15_17850"
     CDS             6445..>7700
                     /locus_tag="JAM15_17850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase"
                     /protein_id="HAT6800109.1"
                     /translation="MADELVLANDRDVRLVIAHWEDFYEPTVLDGITWEIERRGTPSK
                     LEFTIVMDDILQFCEGNSVRLYYKGIGIFYGYIFQKKRDKENHIKIVAYDQLRYFKNK
                     DTYVYSNKTASELVKMLAKDFNLKYNVIEDTKYKISRIEENKTLFDMILTALDDTLRE
                     KKEMYTLYDDFGRITLKNVASMKLDTVMNNDVIEDFDYNSSIDSDTYTKIKLVRDNEE
                     TGKRDVYIAQDSTHMRSWGILQMFDTVDKNMSEAEIKQKCDILLKLYNKKTKSLSLKN
                     VLGDIRVRAGCLVPVFLDLGDIDLQNYMLVEKVKHTFENNSHFMDLTLVDGDEFASYS
                     SSSYSSGNTNNKDEKKNGPEQSIMKKNTGKKVPAIFTAYYPGNNAMEGGKTDCNGKPL
                     DVKSRTVAGPMNREGVKKTWYTDDFL"
BASE COUNT         3069 a          855 c         1537 g         2239 t
ORIGIN      
        1 gctacaacaa cagaaattaa aagtttattt gtagaattta caaagagaat gagagataag
       61 gtaggagcta agtttcaaac agtactatat aagaaaagtg atgcagatta tgaaggtgta
      121 gtatctgtag aaaataaaat aaaagatgct ggactattag agtctagttt aatttattgg
      181 actactggag ctatagctgg atgtgacata aataaatcta atactaataa gcgatatgat
      241 ggcgagtttg atgttgatgt taactatact caaatacaac tcgaagaatc gctaaagagt
      301 ggtaaattta tattccataa agttggagat gaagtccatg tattagagga tataaatact
      361 tttgtatcat ttacagatga taaaaatgac gatttttcaa gtaaccaaag tgttagagta
      421 cttgaccaaa ttgctaatga tattgcaact ttatttaatg aaaagtattt aggtaaagtt
      481 cctaacgata aggcaggaag aataagtttc tggaatgatg ttgttaagca tcataaagaa
      541 ttagaaaata ttagagcaat agaagatttt aaaactgatg atgttagtgt agagcttgga
      601 aatgataaga aaacggtaat agtatctgat ggtgttaaag taattaatgc tatgagtaag
      661 ctttatatga ctgtttcagt tagttaagag aggagtgtga taaatagatg cctaaaaacg
      721 cacctatgaa tgttaaagat acaataagtg catctttagc agaatgtttt gtaacaatag
      781 agggtaaaag atacaatttt atgcaagcta ttaatttaga agctaagatg gaaaaaacaa
      841 aaagtgaagt gccaattcta gggaaaacta caaagggtaa taaaacaaca ggtagtaaaa
      901 ttacaggtag tgcaacattt catttcaata cttctatatt tagagagctt ctctataggt
      961 ataaagaaac tggagaagac atttactttg atatacaagt tactaatgaa gacccaacaa
     1021 gttcagtagg gagacagaca gtaattttaa aagactgtaa tatggattca ggcataatta
     1081 ctaagtttga tgctgatgga gaatatttag aagaagatat ggactttaca tgcgaggatt
     1141 gggaattagt tgagaagttt aaaacattaa tagggatgga ataaaataca catttataaa
     1201 ttatagatgt gtattttata tttatataaa taaggagatg gttaaaatta aagataaata
     1261 caaaatgaaa gactcagttt catttgacta tagtaataaa agaaagatag aagaatgtgt
     1321 aggggagatg tatagaaaag caggattatt tttagtagat attgctgata aactggcact
     1381 tgacacaatt gaaggttcat cattaaaacc aattacaata acaatcaaat tagatgaaaa
     1441 tggtattaca acaatagaaa aacaaacaaa atatttagtt atggaggtag aataatatgg
     1501 gagatttaaa cgctttttta agtcaaaatg caataaaagt agagaataga aagtatgtag
     1561 caagtaatag atttataaat gaagaaggga aagcgataga atgggaaata agagcattat
     1621 cttcagaaga agatgctgca ataagaaaaa actgtccaaa gagagagcca attttaaata
     1681 aaaaaggtaa acatacagga caatacaata ctgtaactga ctacaataaa tattacgaag
     1741 aactaagtat agcctgcaca gtttttcctg atttgaatga ctcaatgtta caagatagtt
     1801 atagagtcat gggggctaat cagctactta aagcaatgtt aactcctggt gaatatacag
     1861 aatatgtcca agaggttttg gatataaatg gatttgataa ttcatttgaa gataaggtag
     1921 aagaagcaaa aaactaattt atgaaggtga ttatgattct aatatagctc attattgcct
     1981 tcataagttt aaatggaaac cgcatgaata tatggattta ccagttgatg aaaaagcatt
     2041 tgttgctgct tctatagata tcaaagtaga agaagaaaaa gaagaagcta aaaaagctga
     2101 caaagatgca aagagaggta gaagaagata atctctggtg taaaaatttt actaatatag
     2161 tataatattg ttaaagaata taatttaggg ggatattata ttatgaagaa aaaagcatgt
     2221 tttttagttt ctatttttat agttatctgt ttggctattg tagggtgttc taattcagaa
     2281 agtctagaga gtagtaacaa agataataaa ccaaaaaaag aagaaaaaaa ggataaagaa
     2341 gtagtcgtag gagaaaaaat tgtttcagat aaaatggaaa tcactattaa taaggttgaa
     2401 ttctcttatg atgtgttacc aaaagttaag gagagtttct atacacatta tcctgctgag
     2461 tcaggtaaag tatatattga tattgctgct gatataaaaa atgctcaaaa acaagagtta
     2521 aattgttcag atttactaac tatcgaagca gactataacg atggatataa atattcatca
     2581 caaacaatag tagaagatga aacaacaggt tttacttatg ataatattac tagtattgac
     2641 cctttagaaa cgaagggagt tagatttata attgattgcc ctgatgaagt aaaaacaagt
     2701 gataagccag tgatattaaa ttttacattt gatgggaata agtatgttta taaaatgaag
     2761 taatttattc aaaaatgaat atattataaa atgaaggaga tattttatga atgatacagt
     2821 agaatatata ttttgtagta agtgtggagt aaagtgttta aaaggaagca agttttgtag
     2881 tgaatgtgga aataaaatag atgatataaa aatgtcaaat gaaagtatta ctaaagataa
     2941 agaatatgac ttaaaaggtg ttagtttaca acatataatg caagaaacta attttataaa
     3001 agcttcgtct ataagaaggt taaaagaatt aactggaata gatttagaag attgtagaaa
     3061 aatattagaa gagccatatc aaaaatatta tgatgaaaat gctgaaatgc ttgaagaaaa
     3121 aagaaaaaaa gaagatgata tgtcaaaaat tagaagggct aaagatgaaa agaaagagaa
     3181 agaaaaaata gcttgttgtc ctagttgtgg ttcaacatct ttatcagcac ataaaaaagg
     3241 ttttggtata ggaaaagcag tagtaggagc aagtctaact ggtggtatag gtttagtagc
     3301 tggaaattta ggagcaaaga aagttagagt tacatgtttg aattgtggaa aacaattttg
     3361 ggcaggtaaa aaataaatat tagagataaa agcatttact tattaagtag atgctttttt
     3421 tataacaaga attagaaagg aggttgaaaa tatggctact atacaaactt caataaaaat
     3481 ttttgatgga atgacaccag ctttccgtaa tatgactaca tctattaaca caacaattaa
     3541 tagtttggag agattacaac aaaggttgca taatcctatt aatgcaggca acatacaaac
     3601 atctcagcag agtttaaata atattgaaaa tattttaact aggatagaac aaaatacagg
     3661 aaaagctggt gagcaacaaa gaaagtttaa tgaagaagtt gacaagggag taggttctac
     3721 agataggtta cttggaaatg tcaaaagatt agctacgact tatttagggt taaaaacttt
     3781 aggaggatta ggtggtttaa gtgaccaaat gaccagtacg aatgcacggt tagcaatgat
     3841 aaatgatggt caattatctg acggaggatt aaataagatg attttccaat ctgctgaaag
     3901 gtctcgtgca tcttatttag acacagcaca aatagtaagc agaatcggaa tgaacgcagg
     3961 aagtgcattt agtagcacta gagagatagt aagtttcgca gagcagctca acaaaaaatt
     4021 cataatcgca ggtgcaagca ctcaagaaat gaattcagca ttactacaat taacgcaagg
     4081 gctaggaagt ggtgtgctaa gaggtgaaga attaaacgct gtatttgagt cagcacctaa
     4141 cattatccgt agtattgcgg attatttgga cgtggatata ggaaaaatta gaggaatggc
     4201 atcagaggga atgttaacag cagacattgt gaaaaactca ttacttgcag cagcggaaca
     4261 gactaatgca gaatttgaaa agatgcctta cacctttaat caaatttgga cttcaattaa
     4321 aaataacgca attatgatat ttggtgttat acagaaaaag atagaacaat ccatgtctag
     4381 taagggattt cggaccttta tagataatct gatagatact ttatatattt taggagctgt
     4441 tgggtttgat atttttaatg gatttattac tctattaagt agcccagttt ttcaaggatt
     4501 cgctaatatg atgctcgttt cgatagggat agttgttcaa ggatttggat ggctattgac
     4561 aactgtagga agtgtcgtta attttattgc gcaaggttgg agtataatac aacctttatt
     4621 aattactagt attgtattat ggggactata caaagctgct attttagcag gtgctatagt
     4681 aacagctatt caagtaggtt ggacagcttt acaagcgttt tggacgaatc tactaaatgg
     4741 ttcattgctt acaaatataa tgatgagtat tgcagctgca atagcaacag atgctttgag
     4801 tggctcaatg atacttttaa tcacaaccat tactattgtt gtaactgtaa tagctttagt
     4861 catagcagca gtttttgtag gcatagctat attcaaccat tttgcgagaa cgagtataag
     4921 tgctattggt gcagtagcag gagcaatatc agttgcagct gcttttatag gaaacttatt
     4981 cattgcaaca gggaatttaa tgatagacat tgtagcttta atatataata ctttagcagg
     5041 ttttgcagag ttctttgcta attttttaga tgacccaatt ggctctgtta taagagcagt
     5101 atctggaatg gctaatgctg tattaggtat tataagaagt atcgcaagtg catttgatac
     5161 agtttttggc tcaaatttgg cagatgcagt aagtggatgg caagatacat tacaaggttg
     5221 gactgacaaa gtagcaggag aagctaagat aaaagttgaa cgaatggacc ctaataaact
     5281 gcattttgac agatttaatt atggaaaagc ttgggatgca ggatataaat ggggagataa
     5341 actagaaact aatataaaag ataaattcga tattagcaaa atagcagaaa aggcaaaaaa
     5401 agatttagga ttagacgacc tttgggacaa aaaatatggt cttggcgatt caataggttc
     5461 agcgggacta aactctccac tcagcgacgc agcaaaagga gcaaaagata cggcaggaaa
     5521 cacagcaaag atggcaaaaa caatggataa aagtcaagaa gaccttaaat atcttagaga
     5581 cattgcagag caagaaacaa tcaatcgata tacaggagta aacattaaaa ttgatatgaa
     5641 caacacaaat aacataagta aagatacgga tgttgacggt atagttaatg tactaacaga
     5701 aaaactgaat gatgctatgg ttgtttcagc cgaaggaata gtttagaaag ggggatatat
     5761 aaatggctta tgacttttat ttagatggag tgcaattacc aatacctcct gcaaaattag
     5821 agattaaagt aacaaataag aataagacag ttgacttaat aaacaccgga gaagtaaaca
     5881 tattaaaaaa agaagggtta tctgaaataa gctttgaagc agagtttaca cataataaat
     5941 taccattcta tcgtggagct tttagggatg tccaattctt tttaagtaaa ctggaattac
     6001 taaagacaga ttgtaagcca tttcaattta ttgtttcaag agaaatgggt ggaaaagtat
     6061 tattcaatac taatatgaaa gtatccttag aggaatataa catagtagaa gatgcagaca
     6121 atggttcaga tacaaaagtt gcaataaagt taaaacaata tagagattac tcaactaaaa
     6181 agttagttct tgcccctcct aaaaatgaga ctggtagacc taatgtaaag atagagccaa
     6241 aacgagttga ttcagtcaat gccacaaaca ctaaaacata tacagtaaaa gcaggggata
     6301 gcctttggtc aatttgtcag aagcaacttg gtaatggttc actatataag aaagtatatg
     6361 aactaaataa atctatgatg gataaggcaa ataagggcaa aaacttaagt aaatatacca
     6421 tttataaagg gcaggtgtta aaacttggct gacgaattag ttttggcgaa tgatagagat
     6481 gtaagattgg ttattgcaca ttgggaagat ttctatgaac caactgtttt agatggaatc
     6541 acatgggaga ttgaaagacg aggaacacct tctaagttag agtttacaat agtcatggat
     6601 gatatactac aattctgtga aggtaactct gtaaggctgt attataaagg aataggtata
     6661 ttttatggat atatatttca gaagaaaaga gataaagaaa atcacattaa aattgttgct
     6721 tacgaccagt taagatattt taaaaataaa gatacttacg tatatagtaa taaaactgca
     6781 agtgaacttg taaaaatgtt agctaaagat tttaatttaa aatacaatgt catagaagac
     6841 actaagtata aaatctctag gatagaggag aataaaactt tatttgatat gatactaact
     6901 gcacttgatg atactttaag agagaaaaaa gaaatgtata ccttgtatga tgattttgga
     6961 agaataacat taaagaatgt tgcatcaatg aaattagata ctgttatgaa caatgatgta
     7021 atagaagatt ttgactataa ttcatcaata gatagtgata cttacacaaa gattaaactt
     7081 gtgagagata atgaagaaac aggaaaaaga gatgtgtata ttgctcaaga ctcaacgcat
     7141 atgaggagtt ggggaatact tcaaatgttt gatacagtag acaaaaacat gagtgaagca
     7201 gagataaaac aaaagtgtga tatacttcta aaactatata ataagaaaac taagtcatta
     7261 agtttaaaaa atgtacttgg tgatattaga gtgagagcag gttgtttagt acctgttttt
     7321 ttagatttag gagatattga tttacaaaat tatatgttag ttgagaaagt aaagcacaca
     7381 tttgaaaata attcgcactt tatggatttg actcttgttg atggagatga atttgcttct
     7441 tattcttcaa gctcatatag tagtggaaat actaataata aagatgaaaa gaaaaatggt
     7501 cctgaacaaa gtattatgaa aaaaaataca ggtaaaaaag ttcctgctat atttactgca
     7561 tattatccag gaaacaatgc aatggaaggt ggaaaaacag attgcaatgg aaagccactt
     7621 gatgtaaaat caagaactgt tgctggtcca atgaatcgag aaggagttaa gaaaacttgg
     7681 tatactgatg attttctaaa
//
LOCUS       DACTZW010000131         7509 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.133, whole genome shotgun sequence.
ACCESSION   DACTZW010000131 DACTZW010000000
VERSION     DACTZW010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7509
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.133"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            127..1686
                     /locus_tag="JAM15_17855"
     CDS             127..1686
                     /locus_tag="JAM15_17855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HAT6800110.1"
                     /translation="MKSKKLLSLGLAMSMFIVACPVSANALDKIDKIQGADKYETAGI
                     IADKQSYTTAILVNADSTMADGLSASGLAGATNAPILLTKKNNIPNATIKRLEKANKV
                     YIIGGESSIDKATENVLKDKNIEVKRLQGSDRIKTSYNVAKEIGAINKVSKVILTNAF
                     KGEPDAMSIASVAVRDKVAIVLTDGKSVPFNTTGVESYVIGGTSSMSDSLVNDTNSTR
                     LGGVDRYDTNKKIVNKFYNGAKEFYIASGTDLVYALVGSTIAKNTPIVLVDDNSNKTA
                     LKGATKITAIGNLNNNAIEQSLNITKNIASPTTGGKYTVKEATERIAYILDEKVFVDY
                     ESAIKAKTDPDECFRYYIKNFTYQGKDYYAIGADDDDFRFLVNMNNLNDILQWYSNDT
                     IKRFDAEGYLKERKAIDMAFEACSSKYGISEDDLILDREEHNISTDFYVVVLYESSGI
                     DSYWVFIDTDTWTVHDIQRLNQNEELVSYHDVNPNTEADKHYNRDVDDVNIIFVPSEN
                     NPFDNDVDGIN"
     repeat_region   1931..3543
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=1931..1959
                     /rpt_unit_seq="gttttatattaactatgtggtatgtaaat"
     gene            complement(3567..3803)
                     /locus_tag="JAM15_17860"
     CDS             complement(3567..3803)
                     /locus_tag="JAM15_17860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6800111.1"
                     /translation="MLRQLRKMRHLTQLELAEKINYNKSYISKLEKGNYKNVTVTTIV
                     DLAIGLEVNYLVIAAIFIMEELKRRKEKNRLAKY"
     gene            complement(4302..4673)
                     /locus_tag="JAM15_17865"
     CDS             complement(4302..4673)
                     /locus_tag="JAM15_17865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAT6800112.1"
                     /translation="MNVSQRIKYLRENMNMSQKELSEKANINTSVMNRIESGERAIRD
                     EELIIFAKIFDVSTDYILGLSDTEKLSIDESYEFIDSLNSDDDIKELIKIALSLDDET
                     RDKMLKIARVFVTEKNKHNDN"
     gene            4839..5042
                     /locus_tag="JAM15_17870"
     CDS             4839..5042
                     /locus_tag="JAM15_17870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007788738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6800113.1"
                     /translation="MKKINHDFIRERRNTLNLSLQNVAVELGFKNASTYFKYETGQYS
                     IRADMLPKLSKILDCDIENFFTN"
     gene            5092..5841
                     /locus_tag="JAM15_17875"
     CDS             5092..5841
                     /locus_tag="JAM15_17875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin Bro"
                     /protein_id="HAT6800114.1"
                     /translation="MIFEGKQVEVFEFNEKILFNPYDCGKCLELTESGVKTALSKMND
                     KQVIKLTNLEVAKYNFRKLNNRGENFLTESGVYKLIFKSQKEEAERFQDWVADEVLPS
                     IRQTGTYNSRKTKDTKDESEIKYMNAQARLKNARAREAKIYLEIAENVDIKEYKQIMY
                     SKATEQLYGEALIPLPVAKKTYSATEIGKILGVSANKVGSLANAYNLKTDEYGIKVWD
                     KAKHSNKQVTTFRYYENVIPIIKKALSSFDN"
     gene            5889..6332
                     /locus_tag="JAM15_17880"
     CDS             5889..6332
                     /locus_tag="JAM15_17880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAT6800115.1"
                     /translation="MSKLGNISNFNLDKQEDKSFNDLDNISICFSEGIRKVVEMNLNN
                     YKNKISKYLNGTSKIELLEPKELTIIVSKGYPDYLMSVEEASKRLKIDKGFGYELIKM
                     GLLKSVDVGATKVSSYELDDFITRNQGKNIKEMLREMKELREGVI"
     gene            6434..6622
                     /locus_tag="JAM15_17885"
     CDS             6434..6622
                     /locus_tag="JAM15_17885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800116.1"
                     /translation="MRIIYKNKIYKVEQDKVLFRITYYDEQKNNRKFNNNKKVKRSVL
                     TRDIELVNLYLPTHLKIK"
     gene            6654..6794
                     /locus_tag="JAM15_17890"
     CDS             6654..6794
                     /locus_tag="JAM15_17890"
                     /inference="COORDINATES: protein motif:HMM:NF015807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Arc family DNA-binding protein"
                     /protein_id="HAT6800117.1"
                     /translation="MQREQTTIRLPKELKEKLEKQASKKGRSFNSILLSILQEFIQNP
                     NV"
     gene            complement(6772..6960)
                     /locus_tag="JAM15_17895"
     CDS             complement(6772..6960)
                     /locus_tag="JAM15_17895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Arc family DNA-binding protein"
                     /protein_id="HAT6800118.1"
                     /translation="MAKMGTYKNPHFAIRIPKEKLDKLKYIAEYNARSANKEIEFLVT
                     KHIEMFEKEHGPIHLDSE"
     gene            7115..7273
                     /locus_tag="JAM15_17900"
     CDS             7115..7273
                     /locus_tag="JAM15_17900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800119.1"
                     /translation="MLANRVRTGLRIPYDLNTKLILIAEERGMSKNSLILQILWDYIK
                     EIENKEVK"
     gene            7273..7500
                     /locus_tag="JAM15_17905"
     CDS             7273..7500
                     /locus_tag="JAM15_17905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800120.1"
                     /translation="MVELVKEFDLQTIKVGNAVKVNCKRFGFEIDCIVVVATEKELNL
                     AYFDEGRGCMEYQALITEDIQDGDYEIKILS"
BASE COUNT         2936 a          759 c         1249 g         2565 t
ORIGIN      
        1 gaaaataatt tattctaatg ttatttaatg tcgttaattg agtggaaata gtttgtgctt
       61 tcgacaacat ataatatatt tttgttatac aatttaattg agtgatatga aaaaggggga
      121 gatgttgtga aatcaaagaa attattatcg ctaggattag ctatgtcaat gtttattgtt
      181 gcttgtcctg tatctgcaaa tgcacttgat aaaattgata aaattcaagg agcagataaa
      241 tatgaaactg ctgggattat tgcagataaa caaagttata ccactgcaat acttgtaaat
      301 gcagatagta caatggctga tgggctaagt gcgagtggac ttgcaggagc tacaaatgca
      361 ccaattcttt tgactaagaa gaataacata ccaaatgcaa ctattaagag attagaaaaa
      421 gctaacaaag tgtacataat tggtggagaa agttctattg ataaagcaac tgaaaatgtt
      481 ttgaaagata agaatataga agttaaaaga cttcaaggta gtgatagaat taagacaagt
      541 tataatgtag caaaagaaat aggagctatt aacaaggtta gtaaagttat attaactaat
      601 gcttttaaag gtgaaccaga tgctatgagt attgcatctg tagctgttag agataaagtg
      661 gctatagtat taactgatgg aaaaagtgtt ccatttaata caactggtgt agaaagttat
      721 gtaataggtg gtacttcatc aatgagtgat agtttagtaa atgatactaa ttcaactcga
      781 ttgggtggag tagatagata tgatactaat aaaaaaatag taaataaatt ctataatgga
      841 gccaaagaat tttatatagc tagtggaaca gatttagtgt atgctcttgt tggctctaca
      901 atagctaaga atactccaat tgtgttagtt gatgacaata gtaataagac tgcgttaaaa
      961 ggtgcaacta aaataacagc aataggaaat ctaaataaca atgctataga acaatctcta
     1021 aacataacaa aaaatattgc cagtccaact actggaggga agtatactgt aaaggaagca
     1081 actgaaagaa tagcttatat tttagatgaa aaagtatttg tagattatga atcagctatt
     1141 aaagcaaaaa cagacccaga tgaatgtttt aggtactata taaaaaactt tacctatcaa
     1201 gggaaagatt attatgcaat tggcgcagat gatgatgatt ttagattttt agtaaatatg
     1261 aataatttga atgatatact acaatggtat tcaaatgata caataaaaag gtttgatgct
     1321 gaaggatatt taaaagagag aaaagcaatc gatatggcat ttgaggcatg ctctagtaaa
     1381 tatggtatta gtgaagatga tttgatacta gatagagaag aacataatat aagcactgat
     1441 ttttatgtgg ttgtattgta tgagagttct ggaatagatt catattgggt ttttatagat
     1501 actgatacat ggactgttca tgatatacag cgtttaaatc aaaatgaaga attagtatca
     1561 tatcatgatg taaacccaaa tacagaagca gataagcatt ataatagaga tgttgatgac
     1621 gttaatatta tatttgttcc atcagaaaat aatccttttg ataatgatgt agatggaata
     1681 aattaaatat ttattataag gagttaaact ataaattgat ataaatattt aaaaataatg
     1741 tatttatgat ataataaaac tatggaaatt ttgcagtgag cgatatttat gataaaatgg
     1801 ggcttagcag ttgaaatata aggtattgag ggtgtatgat aagtgttatc atttgcacta
     1861 ctgcccgctc actgcaaatt taagagagtt gtgtatgcgt aggcattgaa aatactcaac
     1921 ttattttggg gttttatatt aactatgtgg tatgtaaatt aacgtcaccc cttatgagta
     1981 taattataac acttaatgtt ttatattaac tatgtggtat gtaaatgtta caaagactaa
     2041 gaatccactt agtggcttta aaggttttat attaactatg tggtatgtaa atccaactaa
     2101 ggtttaagtt tgttagtaat aaatataagg ttttatatta actatgtggt atgtaaatga
     2161 atataaaata gtgagtatgt caagtcatta tatgacgttt tatattaact atgtggtatg
     2221 taaatagctt ggtacgattt tcgtactgac ctcaaaataa tcgttttata ttaactatgt
     2281 ggtatgtaaa tattgcttac agtttgtttt gttacattaa atattttggt tttatattaa
     2341 ctatgtggta tgtaaattca gctctgtatt cttttgtaga cattgtagcg gtttgtttta
     2401 tattaactat gtggtatgta aataggggac ttttaaaggt ttggaatagt gtttacaatg
     2461 gttttatatt aactatgtgg tatgtaaata aaattggaaa atcaaaagaa ggacaaatag
     2521 gctcagtttt atattaacta tgtggtatgt aaatatctat gaaaaggctt ccttttattt
     2581 tgcaaaaacc tagttttata ttaactatgt ggtatgtaaa ttgctttctt ctttcaagta
     2641 attagtataa gggaggggta gttttatatt aactatgtgg tatgtaaatt actctaaagc
     2701 tttttcatcc caaacataag aaaagaagtt ttatattaac tatgtggtat gtaaatgaga
     2761 aagttatggc tagagcattg attgtagcta atagttttat attaactatg tggtatgtaa
     2821 atttagttcc atgatagaat atcttgtata ttgcgtgtgg ttttatatta actatgtggt
     2881 atgtaaatca caaaaagcta agttagatag cttagaaagt acgcgtttta tattaactat
     2941 gtggtatgta aatgaggcta tcactctttt ttttgatttt ttgtaataag ttttatatta
     3001 actatgtggt atgtaaattt aaatacgccc cctaatttaa aaatacaatc tcatagtttt
     3061 atattaacta tgtggtatgt aaattttgat aatctattaa atctttttgt tgttcttgga
     3121 cgttttatat taactatgtg gtatgtaaat ccaaacaata tagataaatt cccaataact
     3181 ggaggagttt tatattaact atgtggtatg taaatagcta ataacattgc attagaagca
     3241 aaaacagagg tgttttatat taactatgtg gtatgtaaat agagattact gagaaaggca
     3301 ctaaaatttt gacactgttt tatattaact atgtggtatg taaatgtggg attttttgat
     3361 ataactatat aatagtatat tgttttatat taactatgtg gtatgtaaat aatccatacg
     3421 atgcttatca ttccacatac gaggattgtt ttatattaac tatgtggtat gtaaattttc
     3481 aagaatattc tgtatttatt atttatcaag aaaggtttta tattaactat gtggtatgta
     3541 aataattttt aaataataga aatagactag tatttagcta gtctattttt ttcttttctt
     3601 ctttttaatt cttccattat aaatatagct gctataacta aatagttaac ttctaaacca
     3661 attgctaggt caactattgt agtaacagtt acatttttat aattaccttt ttctaattta
     3721 gatatataac ttttgttata attaattttc tctgctaact ctaattgtgt taaatgtctc
     3781 atttttctca gttgtcttaa cataaattta aatcaccttt taatatattt tttagtaaat
     3841 tcagataatt atattatgtg catttttgtg gggaaaagtt tcctattagt cgattttttt
     3901 gttggaaatt tgtgctaaaa tataagcaag aaataactct atctagctag agagaaatta
     3961 aaaattgtag attttgataa gctttgcaat taagtttatg caagtgtgag aactttttta
     4021 aaagataggg gatggttata attaatttca cgaacgtaag ttcttatttt gaaatacata
     4081 agatttataa acaaatacat agtatatggg gatggtgtgt atggaatatt caaaaagatt
     4141 aatattagaa ttagagcatt tgtttaaaaa atttaaagaa gttgaagaag aagaatttaa
     4201 aaaatacgaa aaaatgttaa aagaagaaaa agaaaaaaga gaggattagt tcctctcttc
     4261 taaaaaatgt tatcaacatt tataatacca ttatttcagt tttaattgtc attatgttta
     4321 tttttttctg ttacaaatac tcttgcgatt tttagcattt tatctctagt ttcatcatct
     4381 aaactaagag ctatttttat tagttccttt atgtcatcat cactatttaa gctatctata
     4441 aattcataac tttcatcaat acttagtttt tctgtatctg ataaaccaag aatatagtca
     4501 gtagatacat caaaaatttt agcaaagatt attaactcct catctcttat cgccctttca
     4561 ccagattcta ttctattcat aacactcgta tttatattcg ctttttcaga caattctttt
     4621 tgtgacatat tcatattttc tctaagatat ttaattcttt gacttacatt catctataat
     4681 cacctcgaaa attttctatt atggaaatat aatagcatat ttttctataa tagaaataag
     4741 aaatttctaa aataaatata aaaaagtctt gaatttctat tttagaaatg atattattaa
     4801 aatatagaaa ttgctaaaat agaaattgag gtgaatatat gaaaaagata aaccatgatt
     4861 ttataagaga aagaagaaat acattaaatt tatctttaca aaatgttgca gtagagttag
     4921 gttttaaaaa cgcatcaacc tatttcaaat atgaaacagg tcaatactcg attagagcgg
     4981 atatgttacc taaattatct aagatacttg attgtgatat agaaaatttt tttacgaatt
     5041 aaatttctaa aatagaaata tacaaagggg tagataaaca tgaataactt aatgatattt
     5101 gaaggtaaac aagtagaagt gtttgagttt aatgaaaaaa ttttgtttaa tccatatgat
     5161 tgtggaaagt gtttagaact tacagagagt ggagtaaaaa cagcattaag caaaatgaat
     5221 gataaacaag taataaaact aactaattta gaagttgcta agtacaactt ccgaaagtta
     5281 aacaatagag gcgaaaactt cttaactgaa agtggagtat ataaattaat ctttaaatct
     5341 caaaaagaag aagctgaaag atttcaagat tgggtcgctg atgaagtttt accaagcata
     5401 agacaaacag gcacatacaa tagtagaaaa actaaggata ctaaagatga atcagaaata
     5461 aaatacatga atgctcaagc aagattaaaa aatgcaagag caagagaagc aaagatatat
     5521 ctagagatag cagaaaatgt agacataaaa gaatataaac agattatgta ttctaaagca
     5581 acagaacaac tgtatggaga agcattaata ccattacctg tagcaaaaaa aacttattca
     5641 gctacagaaa taggtaaaat attaggagtt tcagctaata aagttggaag tctagcaaat
     5701 gcttataatt tgaaaacaga tgaatatggc attaaggttt gggataaggc taaacattca
     5761 aataaacaag ttacaacttt tagatattat gaaaatgtga tacctattat aaaaaaagct
     5821 ttaagtagtt ttgataacta gataaaacta acacttcaaa aactaaatac agaatatttt
     5881 gaaaaggagt gagtaaattg ggcaatatat ctaatttcaa tttagataaa caagaagata
     5941 aaagttttaa tgacctagat aatatatcaa tttgtttttc agaaggtatt cgtaaagttg
     6001 tagaaatgaa tttaaataat tataaaaata aaatctcaaa atacttaaac ggaacttcaa
     6061 aaatagaatt attagaaccg aaagaattaa caattatagt aagcaaaggt tatccagatt
     6121 atttaatgtc tgttgaagaa gcaagtaaga gattaaagat agataaaggg tttggatatg
     6181 agttaataaa aatgggactt ttaaaatctg ttgatgtagg agcgactaaa gtttctagtt
     6241 atgaattaga tgattttata actagaaatc aaggaaaaaa catcaaagaa atgcttagag
     6301 aaatgaaaga acttagagag ggggtgattt agttgaatgt aagagttcta atagcttatg
     6361 tacaatattg taagcaatat aataaaaaag caagttttga aggtcttaaa aaatacaaca
     6421 aaggggtaat tgcatgagaa taatttataa aaacaaaatc tacaaagtag aacaagacaa
     6481 agtgttattt agaattacat actatgatga gcagaaaaat aacaggaagt ttaataataa
     6541 taagaaagta aaaagaagtg ttttaacaag agatatagag ttagttaact tgtatttacc
     6601 aacacattta aaaataaagt aagctataaa taattaaaga aaaaggtgat tagatgcaaa
     6661 gagagcagac aacaatacgc ctgcctaaag aacttaaaga aaaattagaa aagcaggcga
     6721 gtaaaaaagg aagaagtttt aatagtattt tattaagcat attacaagaa tttattcaga
     6781 atccaaatgt ataggaccat gttctttttc aaacatttct atatgtttag tgacaagaaa
     6841 ttctatttct ttgttagctg aacgagcatt atactcagct atatatttaa gtttatcaag
     6901 tttttctttt ggtattctaa ttgcaaaatg aggattttta tatgtgccca ttttagccat
     6961 aatatcaact cctttgtgta gtctatttgg caacaattat atcacaaaaa taaatacaaa
     7021 aaatatatag gcaacatata gacaacataa caataaagtg ttatactttg tattaaagat
     7081 aggcaacaca tagataacaa tataggagga aattatgttg gcaaatagag taagaactgg
     7141 attaagaatc ccatatgatt taaatacaaa attaatatta atagcagaag aaagaggaat
     7201 gtcaaaaaat tctttaatat tacaaatact ttgggattac ataaaagaaa tagaaaataa
     7261 ggaggtcaaa taatggttga attggtaaaa gaatttgatt tacaaacaat taaagtagga
     7321 aatgcagtaa aagtaaattg caaaagattt ggttttgaaa ttgattgtat agtagtagta
     7381 gcaacagaaa aagaattaaa tttagcatac tttgatgaag gtagaggctg tatggagtat
     7441 caagccttaa taacagaaga tattcaagat ggtgattatg agattaaaat tttatcttag
     7501 gaggaaata
//
LOCUS       DACTZW010000132         7312 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.134, whole genome shotgun sequence.
ACCESSION   DACTZW010000132 DACTZW010000000
VERSION     DACTZW010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7312
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.134"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            151..1656
                     /locus_tag="JAM15_17910"
     CDS             151..1656
                     /locus_tag="JAM15_17910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HAT6800121.1"
                     /translation="MKVGFDHKKYLEEQSKYILERVNNFDKLYLEFGGKLMGDLHAKR
                     VLPGFDENAKIKVLQHMKEKVEVVICVYAGDIERNKIRGDFGITYDMEVLRLIDDLRG
                     YELDVNSVVITRFEGQPATTVFINKLERRGIKVYKHYPTKGYPSDVETIVSDEGYGAN
                     EYIETTKPIVVVTAPGPNSGKLGTCLSQLYHENKRGNVVGYSKFETFPVWNVPVKHPL
                     NIAYEAATVDLKDVNMIDSFHLETYGEMSVNYNRDLELFPVLKKIIEKITGKESIFQS
                     PTDMGVNRVGFGIIDDEVIRKASIEEIIRRYFKTACEYKKGQVDKGAYDRMKMIMEEL
                     NLKPEDRNVVLPARNYSNKLKESADKNDTCPVVALELEDGTILTGKGSDLMNGTAAVV
                     LNAIKHLANISDDMHLISPVILEPIINLKTKTLASRNVSLSCQEVLTALSICAVTNPT
                     AQFAMEKLALLKGCQAHSTTILNRDDEQTFRKLGIDVTCDPEYPSQNLYYS"
     gene            2046..3143
                     /gene="dinB"
                     /locus_tag="JAM15_17915"
     CDS             2046..3143
                     /gene="dinB"
                     /locus_tag="JAM15_17915"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HAT6800122.1"
                     /translation="MKLHRKIIHIDMDAFYASIEQRDNKKLKGRPVIVGGNPQSRGVV
                     ATCSYEARKFGIHSAMPSAVAYNRCPYAVFVRPRFDVYKSVSEQIRDIFYRYTDLVEP
                     LSLDEAYLDVTKNKKSIDSSIEIAKQIKKDIFREVGLTSSAGVSYNKFLAKIASDLRK
                     PNGLTVITEENAQDFLDKLPVNKFFGVGKVTSNTLKNLGIKTGYDLRCLNLFELENIF
                     KKRGYELYKFARGIDDRPVEPNRVRKSVGAETTLSHNLDIDEEETRNILDELCEEVCH
                     RLKSSEKFGKTLTLKIKYEDFTKITRSLSLEHYIDEYNDIRSGVDNLLRNVEVNGKQI
                     RLLGVTISNLSDKKETYKDITLFEYMDSIQM"
     gene            3406..4542
                     /locus_tag="JAM15_17920"
     CDS             3406..4542
                     /locus_tag="JAM15_17920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437132.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HAT6800123.1"
                     /translation="MIEIRNVTKKIGNNVILDDISLVVETGTLVVLIGSSGCGKTTTL
                     KLINKLIKPTSGEIYINGKPISQENEIELRRKIGYVIQNTGLFPHLTIKENIELIPRL
                     KKEKSVEEIEKRTLQLLEMVGLDSDEFLNKYPSELSGGQQQRIGVARAIATDAEIILM
                     DEPFSALDPITRTSLQEQLFSLQDELKKTIIFVTHDMDEALKIADKICIMKDGRIAQY
                     DTPENILRNPANDFVKDFIGEDRVWDNPEYIKARDIMIKNPIAVNSTRTVTQGIEIMR
                     TSKVDSLLIIDRAKTLKGIVTVKDMKDIDDKSILLADIMSSEPLHVNEGDNLVEILNV
                     MNRNSVGYIPVISDENKLVGLITRSSLLSVLSEQFLEMEVSVLG"
     gene            4535..6082
                     /locus_tag="JAM15_17925"
     CDS             4535..6082
                     /locus_tag="JAM15_17925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAT6800124.1"
                     /translation="MANFFNFILLQKDKIIELLIQHMSLTVTSILIAIIVGVPLGIII
                     SRISSLRKFVLGFVNLVQAVPSMALLGLLVPILGIGSKPAIFMVVVYSLLPIVKNTYI
                     GITSIDPVVLESAKGIGLTRNQTLFKIQFPLALPIIMGGVRISAVTAVGLMTLAAFIG
                     AGGLGYLVFSGVQTVNNNMILAGAIPSCIIALLVDYLFSKIEVAVTPKGLNPKVPKKN
                     YIALKVISVVVVVSMLFVVFSSSFSSKKDTITIGSKDYTEQLILGNVYAELVEKNTNL
                     KVKKNLNLGGSSVAFNAIKSGELDMYVDYTGTLLVNVMKHTPIKDADEAYNVVKDTME
                     KENQLTLLDPLGFNNTYTLAMMPETAEKYGINTISDLTKYGKEFTFSPTLEFENREDG
                     LVGLSRDYGLKFKDVKAMNGSLRYTALDNNESQVIDAFLTDGLIKKFNLKILEDDKNF
                     FVPYYAAPLVREDTLKKYPELEKVMNMLSGKINEETMRELNYQVDELGKSPEDVAHSF
                     LVKEGLV"
     gene            6416..7282
                     /locus_tag="JAM15_17930"
     CDS             6416..7282
                     /locus_tag="JAM15_17930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAT6800125.1"
                     /translation="MDNYKKVKQVLWIILFANFAVALLKIIIGNQIKSYSMTADGFHS
                     LSDGASNIVGLIGIFFASKPKDKNHPYGHKKFEIITSLFISGMLFVIAIKIILSAVLR
                     IANPVVPAITIESLIALIITLFINIFVCMYEYRVGTKLNSYVLISDSLHTRSDIFVSL
                     GVLVTLVGVKLGFPVIIESIVPIIISAFIIYSAYGIFRPSIGILVDRVAVDEDYIKEI
                     VFEFNEVRDVHNIRSRGSKSSIYIDMHVMVDPFISVEQSHDLTHKIEKQIQEEINENA
                     QVIVHIEPFYSF"
BASE COUNT         2778 a          799 c         1302 g         2433 t
ORIGIN      
        1 cataaaacta tcttgaaaaa aattaatctt aattgtataa tattactttg agtgaaaaag
       61 tattaacatt tttttataag atgttttact aaaaaaatat atataaatat actgttatca
      121 acaagaaatt taatttagtg aggtgttaag atgaaagtag gatttgacca caaaaaatat
      181 ttagaagagc agtctaaata catcttagaa agagtaaata attttgacaa actttattta
      241 gagtttggag gaaaattgat gggagacctt catgcaaaaa gagtacttcc agggtttgat
      301 gaaaatgcaa agataaaagt attacaacat atgaaagaaa aagttgaagt tgtaatttgt
      361 gtctatgcag gagatataga aagaaacaaa ataagaggag actttggtat cacttatgat
      421 atggaagttt taagattaat agatgattta agaggttatg aactagatgt aaatagtgta
      481 gtaattacta gatttgaagg acaacctgct acaactgtat ttataaataa attagaacgt
      541 agaggaatta aagtttataa gcattatcca acaaagggat atccgtcaga tgttgagact
      601 atagttagtg atgagggata tggagcaaat gaatatatag aaaccacaaa gccaatagta
      661 gtagtcacag caccaggacc taatagtgga aaacttggta cttgtctaag tcagttgtat
      721 catgaaaata aaagaggtaa tgtagttgga tattctaagt ttgagacatt cccagtttgg
      781 aatgtacctg taaaacatcc tttgaatata gcttatgaag cagctacagt tgatttaaaa
      841 gatgtgaata tgatagattc attccacctt gaaacgtatg gtgaaatgtc agtaaactac
      901 aatagagatt tggaattatt tccagtgctt aaaaaaataa tagaaaagat aactggaaaa
      961 gaatcaattt tccaatctcc aactgatatg ggtgttaata gagttggctt tggaataata
     1021 gatgatgaag taataagaaa agcttctata gaagaaataa taagaagata ctttaaaact
     1081 gcctgtgagt ataaaaaggg acaagttgat aaaggcgctt atgatagaat gaaaatgatt
     1141 atggaagagc ttaacttaaa gccagaagat agaaatgttg tattacctgc tagaaattac
     1201 agtaataaat taaaagaaag tgccgacaag aatgatactt gtcctgtagt tgcattagaa
     1261 ttagaagatg gtacaatatt aactggtaag ggttctgatt taatgaatgg aacagcagca
     1321 gtagtattaa atgccattaa acatttagcc aatatatctg atgatatgca cttaatatca
     1381 cctgtaatat tagaacctat cataaactta aaaacaaaga ctttagctag tagaaatgtt
     1441 tcacttagtt gccaagaggt gttaactgca cttagtattt gtgctgtaac taatccaact
     1501 gcacagtttg ctatggaaaa gttagcatta ttaaaagggt gtcaagctca ttctactact
     1561 atattaaata gagatgatga acaaacattt agaaagcttg gtatagatgt aacttgtgac
     1621 ccagaatatc cttcacaaaa tctttactat agttaaaatt atataaaaaa atatgggctg
     1681 ttttaaagta atagtttgag cagtccatta caattataat aaaatcagta ggctgtcttg
     1741 tataagacag tcttttgttt ttaaaacatc ccataaatta aatatatata ctgttatcca
     1801 taaggaattt taaatttagt tccttggaat acctattgta aagcttttat atagtttttg
     1861 caagtgtttt taaggatttt ttataaatta tattgaagtt aatggattat agatggtttt
     1921 atttatggaa aatatgaata tataaagaaa atgatgaaaa aataccaaaa agaaacataa
     1981 gtttggttta cttaaaaagt aatataaata aaattaatct atttatactt taaaaggtga
     2041 taatgatgaa acttcataga aaaataattc atatagatat ggacgctttt tatgcatcta
     2101 tagaacaaag agataataaa aaattaaaag gaagacctgt tattgtcggt ggaaatccac
     2161 aaagcagagg tgtggttgca acgtgttctt atgaagctag aaaatttgga atccattcag
     2221 ctatgccatc agctgtagct tacaataggt gtccatatgc agtttttgta agacctagat
     2281 ttgatgttta taagagtgtg tcagagcaaa taagagatat attttataga tacacggatt
     2341 tagttgaacc attatcttta gatgaagctt acttagatgt aacaaaaaat aaaaaaagta
     2401 ttgattcatc aattgagata gcaaagcaaa taaaaaaaga tatatttaga gaagttggtc
     2461 ttacttcttc agctggtgtg tcatacaata agtttcttgc taagattgca tcagacttaa
     2521 gaaagccaaa tgggttaact gtaataaccg aagaaaatgc ccaggacttt ttagataaat
     2581 tacctgtgaa taaatttttt ggtgttggaa aagttacttc aaatactctt aaaaatttag
     2641 gtataaaaac tggatatgat ttaaggtgtt taaatttatt tgaacttgaa aatatattca
     2701 aaaaaagagg ttatgaatta tataaatttg ctagaggaat agacgataga ccagtggaac
     2761 caaatagggt tagaaaatct gttggggctg agactacatt aagtcataat ttggatattg
     2821 atgaagaaga aacacgcaac attcttgatg aactttgtga agaagtatgt catagattaa
     2881 aaagctctga gaagtttgga aaaacattaa cattaaaaat taaatatgag gactttacaa
     2941 agataactag aagccttagt ttagaacact atattgacga atataatgat ataagaagcg
     3001 gtgtagataa tttgttgaga aatgttgagg ttaatggaaa acaaattagg ctattgggag
     3061 ttacaatatc aaacttaagt gataaaaaag aaacttataa agatattaca ttatttgaat
     3121 acatggatag tatccaaatg tgagttttgt ttaaatgaaa taacactagc tttaatacta
     3181 tataattgag gttagtgtta ttttatgaat atttttatac tttttgtttt ttgacattat
     3241 atattatata ctatatatag atactttata tttgtagcaa tattcagaca aatagtgacc
     3301 taaaaatcgt actttgttta cataaataaa atagtatgat ataattataa aaacaactta
     3361 taatattgga gaaggttgct tgttcgaaaa aggggatgat aaattatgat agagataaga
     3421 aatgtaacaa aaaaaatagg aaataatgtt atattagatg atatttctct agttgtagaa
     3481 acaggtacat tggtagtttt gattggttca agtggttgtg gaaagactac tactttgaag
     3541 cttataaaca aattaataaa acctacatct ggtgagatat atattaatgg caaaccaatt
     3601 tctcaggaaa atgaaataga acttagaaga aaaataggat atgttataca gaacacaggc
     3661 ctattccctc atcttacaat aaaagaaaat atagagctaa ttccacgcct aaaaaaggaa
     3721 aaatccgttg aagaaattga aaaaagaacg ttgcaactac ttgagatggt aggacttgat
     3781 agtgatgaat ttttgaataa gtatccttca gaacttagtg gtggacagca acaaagaatc
     3841 ggtgttgcaa gagccattgc tactgatgct gaaataatat tgatggatga gccgtttagt
     3901 gctttagacc caataacgag aacatcttta caagaacaat tattttctct tcaagatgaa
     3961 ttgaaaaaaa ctataatatt tgtaactcat gatatggatg aggctttaaa gatagctgat
     4021 aaaatttgta ttatgaagga tggaagaata gcacaatatg atactcccga aaatatactt
     4081 agaaatcctg caaatgactt tgtaaaagat tttatcggag aagatagagt ttgggataat
     4141 ccagaatata taaaagcaag ggatattatg ataaaaaatc ctattgctgt taattctact
     4201 agaactgtaa ctcaaggaat agaaattatg agaacgagta aggttgatag cttactaatt
     4261 atagatagag caaaaacatt aaaaggtatt gttactgtaa aagatatgaa agatattgat
     4321 gataagtcaa tattacttgc tgatattatg tcaagtgagc ctttgcatgt aaatgaaggt
     4381 gataatttag tagaaatact aaatgtaatg aatcgtaatt cggttggata tattccggtt
     4441 atttctgatg aaaataaact ggtagggctt attactagaa gtagtttact ttctgtttta
     4501 agtgaacaat tcttagaaat ggaggtgagt gttcttggct aattttttta actttatact
     4561 attacaaaaa gataagatta tagaactttt aatacaacat atgagtctaa ctgttacatc
     4621 tattttaata gctataatag ttggtgttcc tcttggaata attatttcaa gaatctcatc
     4681 tcttagaaag tttgtacttg gatttgtaaa cttagtccaa gcagttccgt ctatggcact
     4741 tttgggtctt cttgtaccta tacttggtat aggaagtaaa ccagccatat ttatggtagt
     4801 ggtttattca ttactaccaa ttgtaaaaaa tacgtatata ggtataacaa gtattgaccc
     4861 agtagtatta gaatcagcta aaggtattgg tcttacaaga aatcagacat tatttaaaat
     4921 acaattccct ttagcacttc ctataataat gggtggagtt agaatatctg cagttacagc
     4981 tgttggtttg atgactcttg cagcatttat aggtgctggt ggtttaggat atttagtatt
     5041 ttcaggggtt caaactgtaa ataataatat gattttagca ggggcaattc catcatgtat
     5101 aattgcactg ttagttgatt atttatttag taaaattgaa gttgcagtta ctccaaaagg
     5161 attaaatcca aaagtaccta agaaaaatta tatagcactt aaagtaatat ctgtagtggt
     5221 tgttgtttca atgctgttcg ttgtttttag ttctagtttt tcaagtaaaa aagatacaat
     5281 aactattggt tctaaagatt atacagaaca acttatactt ggtaatgttt atgctgaatt
     5341 agtagaaaaa aatacgaatc ttaaagttaa gaagaattta aatctaggtg gttcatctgt
     5401 tgcatttaat gcaattaaat ctggtgaatt agacatgtat gttgactata caggtacact
     5461 tttggtaaat gtaatgaaac atactccgat taaagatgct gatgaagcat ataatgttgt
     5521 aaaagatact atggaaaaag aaaatcagtt aactttactt gaccctcttg gatttaataa
     5581 tacttacaca ttagccatga tgcctgaaac tgctgaaaag tatggaataa atactatttc
     5641 tgatttgact aaatatggta aagaatttac attctcacca actttggagt ttgaaaatag
     5701 agaagatggt cttgtagggc tttctagaga ttatggttta aaattcaaag atgtaaaagc
     5761 aatgaatgga agtttaagat atacagcttt agataataat gaatctcagg ttatagatgc
     5821 atttttaact gatggtctta ttaaaaagtt taatcttaag atattagagg acgataaaaa
     5881 cttctttgta ccatattatg cagcaccatt agtgagagaa gatactttga agaaatatcc
     5941 tgagttagaa aaagttatga atatgctttc aggaaaaata aatgaagaaa ctatgagaga
     6001 acttaactat caagtggatg aacttggtaa atcaccagaa gatgttgctc attcattctt
     6061 agttaaagaa ggcttagtat aaaaaattaa tagtttatat caaaaattta agggagtgtc
     6121 tcaaaatgaa ctttttagtt tatgaggcac tcttttttat atgaaatcaa atatatttta
     6181 tcattttaac aataaaaaag aagtttatct ttattttgag atagcctctt atttttatgt
     6241 ataccaaaac catacctatg atttttattt ataattaagt ttcaaataga atgaacaagt
     6301 acaaccaatt ttgaatataa atatagtaaa tgtgcttata tacgatttta ttgtctggtt
     6361 gattgatatt gatagatagc tttctttatt gaatcgaagg gagggggaat ttgttatgga
     6421 taactataag aaagtgaagc aagtattgtg gataatttta tttgctaatt ttgcagtagc
     6481 attattaaaa atcattattg gtaatcaaat aaaaagctat agtatgacag cagacggatt
     6541 tcattcttta tcagatggag catctaatat agtagggctt ataggtattt tctttgcatc
     6601 taaaccaaaa gataaaaatc atccttatgg acataaaaag tttgaaataa taaccagttt
     6661 atttataagt ggtatgttgt ttgttatagc aattaagata attcttagtg cagtgttaag
     6721 aatagctaac ccagttgtac ctgctataac tatagaaagt ttaattgctt taattattac
     6781 actttttata aatatttttg tatgtatgta tgaatataga gttgggacta aactaaatag
     6841 ttatgttttg atttcggatt cattgcatac aagaagtgat atatttgtgt ctctaggtgt
     6901 attggttact ttggttggtg tcaagttagg atttccagta ataatagaat ctatagttcc
     6961 tattattatt tctgcattca taatttattc ggcttatgga atatttaggc catctattgg
     7021 aattttggtt gatagggtgg ctgtagatga ggattatata aaagaaattg tatttgaatt
     7081 taatgaggta agggatgttc acaatatcag aagtagaggc agcaaaagtt ctatttatat
     7141 tgacatgcat gtaatggtag acccatttat aagtgtagag caatctcatg atttaacaca
     7201 taaaattgag aaacaaatac aagaagaaat taatgaaaat gctcaagtaa tagtccatat
     7261 tgaacctttt tatagttttt aacctagcta tagaatgcaa gttataaaaa at
//
LOCUS       DACTZW010000133         7245 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.135, whole genome shotgun sequence.
ACCESSION   DACTZW010000133 DACTZW010000000
VERSION     DACTZW010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7245
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.135"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            5..655
                     /locus_tag="JAM15_17935"
     CDS             5..655
                     /locus_tag="JAM15_17935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HAT6800126.1"
                     /translation="MKAEKTSIYPIIKNNLNKISIVEYKKGQRFVASDKDLQEVFFII
                     EGVALVECTTRGGNKFLVDIVPENEFIGKISYIYEHNLKCDIFAKTNIKLFRFEKNVF
                     EEFYLKPDFIALFHRKCTRRIYELYKTRMVRELFSCTEVIAYCISNKQENNVCNIKAI
                     RNFSEIYSISRKSRYHSLLKLTEKEIVKKMGNTYEILNYDELHKLAFEVKEFLEDE"
     gene            complement(795..2171)
                     /locus_tag="JAM15_17940"
     CDS             complement(795..2171)
                     /locus_tag="JAM15_17940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HAT6800127.1"
                     /translation="MQELFSLKDENKRFYKILLSLCIPIIIQNLISTSVNVIDTIMIS
                     SLGETSVASVGVANQFFFLFNMSLSGITGGAGVFISQFYGKKDVSNIRKVTGLTCVLA
                     IVLSFVFVIPALLTPKPIIHIFSYDSEVVKLCIDYFSIAVFSYPLIAVSTVFSTGSRG
                     VRNPKLGMICSAFALVTNVILNYGFIFGNFGLPALGVKGAALATVIARICELILMITY
                     VYLYKKDYILKFGLKNLKAIDKIFIKSFSSKSFPIFVNDSVWAIGTVLYSVAYARAGT
                     SAIAASQIATSTGNFFIMTAVCIASGASIMLGNELGADHIKRAIEYAKKFSILVFSAG
                     LILGIILILNIPLLLKMFSVSDSLASDITKIFFIMGILMALKSFNTLVIIGILRSGGD
                     TKYALFLELGCMWLASIPLTFIAAFKGAPIFVLVLLTYSEEVVKFIFGVPRALSKKWA
                     INIVKEID"
     gene            complement(2187..4100)
                     /locus_tag="JAM15_17945"
     CDS             complement(2187..4100)
                     /locus_tag="JAM15_17945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002845767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAT6800128.1"
                     /translation="MIVLSCNNLNKSFGIDSILENISFTVNEGDKIGIIGVNGTGKTT
                     LFKIISGIYGYDSGDIYTSKDCEIGYLEQNTNFYSDNTILEEVLEVFKNLIEMESYLR
                     ELEVKISEESTKTNSPIIEKIMDEYSHKLELFSDLNGYGYKSEAKGVLKGLGFSDNDM
                     DKPISILSGGEKTRVLLGKLLLKKPTLLLLDEPTNHLDSEAIEWLEVFLKQYKGTVML
                     ISHDRYFLDQSVNRVFEVHNKKLKVYNGNYSKFVELSKIEKELELKKFEDQQKEIKKQ
                     EESIERLKAYGREKHLKRARSKEKALDKVDVLDKPEAYRKKARIQFTPSVQSGNDVLQ
                     IRDVSMGYGERILFKDLDLDIYRGEKVALIGANGVGKSTLFKIITNELQPLSGNIKFG
                     TNVHVSYFHQEQKTLNLDNTIIDEIWENNTHLTQTTLRNMLGAFLFVDEEVFKKISTL
                     SGGERARVAILKLILSNANLLLLDEPTNHLDIDSKEVLEEALTNYDGTIFTISHDRYF
                     LNTVVDKILVLDENGITEYLGNYDYYIDKKRQIQEMSIIEEKEEKTRTQIKDEKRKER
                     EQREIEKKNRIKRQNIEKEIEKLEIEIEKLDILLCQEEVYSNPDKAKEVSQEKINLEN
                     NLASLYDEWEEFM"
     gene            4239..4868
                     /locus_tag="JAM15_17950"
     CDS             4239..4868
                     /locus_tag="JAM15_17950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HAT6800129.1"
                     /translation="MGNKNISMAVIRRLPKYHRYLGDLLDRDIQRISSKELSDIIGFT
                     ASQIRQDLNNFGGFGQQGYGYNVEALHTEIGKILGLDRPYNAVLVGAGNLGQAIANYA
                     GFRKAGFEIKALFDANPRMIGLKIREFEVLDSDTLEDFIKNNNIDIAVLCIPKNGAQE
                     VINRVVKAGIKGVWNFAPLDLEVPKGVIVENVNLTESLFTLSYLMKEGK"
     gene            5016..5546
                     /locus_tag="JAM15_17955"
     CDS             5016..5546
                     /locus_tag="JAM15_17955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylmethanofuran dehydrogenase"
                     /protein_id="HAT6800130.1"
                     /translation="MEELWKKAIKFHGHECPGLAIGFKAALAAREYLGCKQSGDEEIV
                     CISENDACGIDGIQVVLSCTMGKGNLLLRMTGKSVYHFFNRENGKSIRIYVKSKPFQM
                     DREGYKKYLLESDFEEIFEITDTKLRLPEKARIFKSLKCEVCGEFASEQYIRIEEGKK
                     VCLDCFNKYERFYEEY"
     gene            complement(5722..5892)
                     /locus_tag="JAM15_17960"
     CDS             complement(5722..5892)
                     /locus_tag="JAM15_17960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009525956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HAT6800131.1"
                     /translation="MAYKITDACISCGACEAECPVSCISAGDDAYVIDAGSCIDCGSC
                     AGACPVDAPQPE"
     gene            6177..7244
                     /locus_tag="JAM15_17965"
     CDS             6177..7244
                     /locus_tag="JAM15_17965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HAT6800132.1"
                     /translation="MKNKLVYICIMSLLLFVVGCSNNPNKESTIKKDSKNNQSQVKEE
                     KREPVKKDITISFAGDVTMGNYKGSSYYGSFDHEFKRQGEDYNYFLKNVKPVFEKDDL
                     TVVNLEGPLTTASNAKEKKFAFKGKPGYVNILKSGSVEAVSIANNHSEDYFEEGMKDT
                     QFILDENKINYFGLGKDAVVDVKGIKVGLLGYNGLSTEYNEKNLKQMEDDIKSLKKKS
                     DVVVVYFHWGIELDYYPDKKQKDFAHYAIDKGADLVMGSHPHVIQGIEKYKNKYIAYS
                     LGNFCFGGNKNPSDTDSYIYQQTFTFSDNKLTSIKEPNIIPTSITSSNSRNNYQPKIL
                     DGSEKDRVLNKLEKISKDLNK"
BASE COUNT         2734 a          966 c         1054 g         2491 t
ORIGIN      
        1 tttgatgaaa gcagaaaaaa caagtatata tccaattatt aaaaataatt taaacaaaat
       61 atcaattgtt gaatataaaa agggtcaaag atttgtagca tcagataaag acttacaaga
      121 agtgttcttt ataatagagg gagttgcatt agtggagtgt actactagag gaggaaataa
      181 atttcttgtt gacattgtac ctgaaaatga atttataggc aaaattagtt acatatatga
      241 acataatttg aaatgtgata tatttgcaaa gactaatata aaattatttc gatttgaaaa
      301 aaatgtattt gaagagtttt atctcaaacc agattttatt gcactatttc acagaaaatg
      361 tacaagaaga atatatgaat tatataaaac cagaatggta agagaactat tttcttgcac
      421 agaagttatt gcctattgta tatcaaataa acaagaaaat aatgtctgca atataaaagc
      481 tattcgtaat ttcagtgaaa tctattcaat tagtagaaaa agtagatacc attctctgct
      541 aaagttaact gaaaaggaga tagtaaaaaa aatgggtaat acatatgaaa ttttaaacta
      601 tgatgaattg cataaattgg catttgaagt aaaagagttt ttggaagatg agtaaaaatt
      661 gttacttaat caaaataaag tataataatt tctgtaaaaa atagagatag tctcactgaa
      721 aatcaaaaat actttagtta ttttcaatga gactgtttag aaatattgta tacttataat
      781 gtatagtata attattaatc aatttccttt actatattaa tagcccattt tttagataat
      841 gctctaggaa caccaaatat aaacttaacc acttcttcac tataagtgag caaaacgagt
      901 acaaatatag gtgcaccttt aaatgcagct ataaaagtta gaggaataga agctaaccac
      961 atacatccta attctagaaa tagagcatat ttagtatctc ctccacttct taaaatacca
     1021 attataacca atgtattaaa agatttaaga gccattagta ttcccattat aaagaatatc
     1081 ttagttatat cagaagctaa gctatcagaa acactaaaca tttttaataa taatggtata
     1141 tttaaaatta aaataattcc aagtattaaa ccagctgaaa atacaagtat agaaaacttt
     1201 ttagcatatt caatggctct tttaatatgg tcagctccaa gttcatttcc aagcataata
     1261 gatgcaccag atgcaataca tacagctgtc attatgaaga aattacctgt actggttgct
     1321 atctggctag ctgctatagc agaagtacca gctcttgcat atgcaacaga atacaggaca
     1381 gttccaattg cccatacaga gtcatttaca aatataggaa agctttttga tgaaaaagat
     1441 tttataaaaa ttttatcaat agcttttaga ttttttagac caaactttaa tatatagtct
     1501 tttttataaa ggtaaacata agtaatcatt aaaattaatt cacatattct agcaataaca
     1561 gtagctagag cagcaccttt tacacccaat gcaggaagac cgaagttacc aaatataaat
     1621 ccataattta aaataacatt tgttacaagt gcaaatgcac tacaaatcat acctaactta
     1681 ggatttctaa cacctcttga accagtacta aatacagtac ttacagcaat taatggataa
     1741 ctaaatactg caatactaaa gtaatctata caaagtttta ccacctcaga atcatacgaa
     1801 aatatgtgta taattggctt tggtgttagt aaagcaggaa taacaaatac aaaacttaaa
     1861 acaattgcca atacacaagt aagacctgtg acttttctta tattactcac atccttcttt
     1921 ccataaaact gtgaaataaa aactccagca cctcctgtga taccagataa ggacatatta
     1981 aaaagaaaga aaaattggtt tgcaactcca actgaagcta cagatgtttc ccccaaacta
     2041 cttatcataa ttgtatctat tacatttaca gaagtagaaa ttaagttctg tatgataata
     2101 ggtatacata aagatagaag tattttataa aatcttttat tttcgtcttt taaagaaaat
     2161 agttcttgca aataatcctc tcctttttac ataaattctt cccactcatc atatagagag
     2221 gcaaggttat tttctaaatt aattttttct tggctaactt ctttagcttt atctggatta
     2281 gagtatactt cttcttgaca taaaagtata tctaattttt caatttcaat ctctaacttt
     2341 tcaatttctt tttctatatt ttgtcttttt attctatttt tcttttctat ttctctttgt
     2401 tctctctctt ttcttttttc atcttttatt tgagttctag ttttttcttc tttttcttct
     2461 ataatactca tctcttggat ttgccttttt ttatctatat aataatcata atttcccaga
     2521 tattcagtaa ttccattttc atctaaaact aaaattttat caacaacagt atttagaaag
     2581 tatctatcat gtgatattgt aaatatagtc ccatcataat tagttaatgc ctcttcaagg
     2641 acttccttag aatcaatatc taggtgatta gtaggctcat ctaataacaa taagtttgca
     2701 tttgatagta taagtttaag tatggcaact ctagctcttt ctccaccact caatgtagaa
     2761 atcttcttaa aaacttcttc atctacaaat aaaaatgccc ctaacatatt tctcaaagta
     2821 gtttgagtaa gatgagtatt attttcccaa atctcatcaa ttattgtgtt atctaaatta
     2881 agagtttttt gttcctgatg gaagtaggaa acatgtacat tagttccaaa tttaatattg
     2941 ccactaagag gttgtagttc attagttatt attttaaata atgtagattt gccaacacca
     3001 tttgcaccta taagtgcaac tttttcccct ctatatatat ctaaatccaa gtctttaaaa
     3061 agtattcttt ctccataacc catagataca tctctaattt gaagaacatc attaccactc
     3121 tggacagaag gcgtaaattg tatacgagct tttttcctat aagcttctgg tttatctaaa
     3181 acgtctacct tgtctaatgc tttttcttta cttcttgcac gctttaggtg tttttctcta
     3241 ccataagctt ttagtctttc aattgattct tcttgctttt ttatttcttt ttgttggtct
     3301 tcaaatttct taagctctag ttctttttct attttagata actcaacaaa tttagagtag
     3361 ttaccattat atactttaag ttttttgttg tgaacttcaa aaactctatt tacggattgg
     3421 tctaagaaat atctatcatg agatattaac atgacagtcc ctttatattg ttttaaaaat
     3481 acttctaacc attctattgc ttcagagtct aagtggttag taggttcatc aagtaacaat
     3541 agagttggtt tcttaagaag taattttcct aaaagaactc tagttttttc accaccagaa
     3601 agtatgctta ttggcttatc catatcattg tcactaaatc ctagtccttt tagaactcct
     3661 ttggcttcag atttatatcc atatccattt aaatctgaaa ataattctag tttatgtgaa
     3721 tattcatcca tgattttttc tataattgga gagtttgttt ttgtactttc ttcagatatt
     3781 ttaacctcca attctcttaa ataggattcc atttctatca aatttttaaa aacttctagt
     3841 acttcttcca aaatagtatt atccgaataa aaattggtat tttgttctaa atatccgatt
     3901 tcacaatctt tagaagtgta aatatctcca ctatcatatc cataaattcc tgaaattatt
     3961 ttaaataaag tagtttttcc agtaccatta acaccgatta taccaatttt atcgccttca
     4021 tttactgtaa aactaatatt ttctaatata gaatctatac caaaactttt atttaagtta
     4081 ttacatgaca aaacaatcat aaatttctac ctccttgaac tatctaaaat tataatgttt
     4141 tgatataata taatcaaggt tatatgtatt agttttgaaa aagaaatatt ttattgtgaa
     4201 tcaaacaaaa aagaggacac ttttaggagg tgaagatgtt gggaaataaa aatatatcaa
     4261 tggcagttat aagaaggctc ccaaaatatc atagatatct tggagactta ttagataggg
     4321 atatacaaag aatatcttct aaagaattga gtgatataat agggtttacc gcttctcaaa
     4381 taagacaaga tttaaacaac tttggtggat ttggacaaca aggatatggt tataatgtag
     4441 aagctcttca tactgagata ggtaaaattc ttgggttgga tcgaccatac aacgcagttc
     4501 ttgtaggagc aggtaactta ggacaagcta tagccaatta tgcaggattt agaaaagctg
     4561 gattcgagat aaaagcttta tttgatgcaa atcctagaat gataggttta aagataagag
     4621 agtttgaagt attagattca gatactttag aagactttat aaaaaacaat aatatagata
     4681 ttgctgtatt atgtatacct aaaaatggag cacaagaagt tattaataga gttgtaaaag
     4741 ctggaatcaa aggtgtatgg aattttgcac ctttagattt agaagttccg aaaggtgtta
     4801 tagttgaaaa tgtaaactta acagaaagtt tatttacctt atcgtattta atgaaagaag
     4861 gaaagtagac aacttaaaca tattaataat gagcagttgt gaagagtatt gagaaagtca
     4921 gaagatttaa tattaaatcc tctggctttt tgaaatatta ggataaaaat ttaaataatg
     4981 tatggaaata aacaatatta aggagagtgg tttttgtgga ggaattatgg aaaaaggcaa
     5041 ttaaatttca tggtcatgaa tgtccaggat tagctatagg atttaaagca gcacttgcag
     5101 caagagaata tttaggatgt aaacagtcag gagatgagga aattgtatgt atttctgaaa
     5161 atgatgcttg tggaatagat ggtatacaag tcgtgctaag ttgcacaatg ggtaaaggaa
     5221 atttactact taggatgact gggaaatcag tatatcattt ctttaatagg gaaaatggaa
     5281 aatctataag aatatatgta aagtcaaagc catttcaaat ggatagagaa ggatacaaaa
     5341 agtacttatt agaaagtgat tttgaagaaa tatttgagat tacagatact aagttaagac
     5401 ttcctgaaaa agcaagaata tttaaatctc ttaaatgtga agtgtgtggt gaatttgcat
     5461 ctgagcaata tataaggatt gaagaaggaa agaaagtatg tcttgattgc tttaataaat
     5521 atgaaagatt ttatgaggag tattaaaatt ataaattaga ttaaagttaa aagtattaga
     5581 tatgtgctaa cagtatttta agatgaatta ggtagcaaca taataaagta tataaataat
     5641 attaattgaa tcatacataa ttaaaaagag gctgattagt atttataaaa taaaatcagt
     5701 ctctttatga ataacgaatt attattctgg ttgaggtgca tctacaggac aagctcctgc
     5761 acaagaacca cagtctatac aagaaccagc atctataaca tatgcgtcgt ctccagctga
     5821 tatacagcta acagggcatt cagcctcaca agcaccacag cttatacaag cgtcagtaat
     5881 tttatatgcc attttgaaat cctccctttt atatgtattg taattcaata acattataac
     5941 aaatattatt gaatataaca attaaattaa ttctacaaca aaaactttat tatgatattc
     6001 ttgttttaaa gttttacaat aaagtttaat ctgcttatat ttttatttat tttaaagaag
     6061 tttattttaa aaataaaatt aaatttaaaa agttatgtat tgattatatt taaaaatgtt
     6121 atactctaaa aaagtatatt ttatttaaaa atttattaat acaaaggaga tttactatga
     6181 aaaataaatt agtttacata tgtattatga gtctattgct atttgtagta ggatgttcta
     6241 ataatccaaa taaggaaagt accattaaaa aagactctaa gaataaccaa agccaagtta
     6301 aagaagaaaa aagagaacct gtgaaaaaag atataactat aagtttcgct ggtgatgtaa
     6361 ctatggggaa ctataaaggt tcatcatatt atggcagttt tgaccatgaa tttaaaagac
     6421 aaggagaaga ttacaattat tttcttaaaa atgtaaaacc tgtatttgaa aaagatgact
     6481 taacagtggt taatttagaa ggtccactta ctacagcgtc aaatgcaaaa gaaaaaaaat
     6541 ttgcatttaa aggaaagcct ggatatgtaa atattttaaa atctggaagt gtagaggcag
     6601 taagtattgc aaataatcat tcagaagatt attttgaaga aggaatgaaa gatacacagt
     6661 ttatattgga cgagaataaa ataaattatt ttggattagg gaaagatgct gttgtagatg
     6721 tcaaaggaat taaagtgggt ctattagggt ataatggatt atcaactgaa tataatgaaa
     6781 aaaatttaaa acaaatggaa gatgatatta agtccttaaa aaagaaatcg gatgttgttg
     6841 tagtgtactt tcattggggg atagaattag attattatcc agataaaaaa caaaaagatt
     6901 ttgctcatta tgctatagac aagggagcag atttagttat ggggtctcac ccgcatgtga
     6961 ttcaaggaat agaaaagtat aaaaataagt atatagctta tagtctaggg aatttttgct
     7021 ttggaggaaa taagaatcct tctgatacag atagttatat atatcaacaa acctttactt
     7081 tttcagataa taaattaact tcaattaaag agccaaatat aataccaact tcaataacat
     7141 ctagtaactc cagaaataat tatcaaccaa aaatattgga tggaagtgag aaggatagag
     7201 ttttaaataa acttgaaaaa ataagcaaag atttaaataa ataaa
//
LOCUS       DACTZW010000134         7173 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.136, whole genome shotgun sequence.
ACCESSION   DACTZW010000134 DACTZW010000000
VERSION     DACTZW010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7173
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.136"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(155..1006)
                     /locus_tag="JAM15_17970"
     CDS             complement(155..1006)
                     /locus_tag="JAM15_17970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HAT6800133.1"
                     /translation="MALVTTTSMLKKAQDEGYAVGAFNVENMEMVIAVIEAAEELNSP
                     VILQTTPSTVKYAGLDYYLANAKVAAERVKIPVAMHLDHGSSFDLAMKALRSGYTSIM
                     IDGSHESFENNISISKSVVKACSPSLIPVEAELGKVGGKEDDLDGGNSNDYTNPKEAK
                     EFVDRTGISSLAIAIGTAHGLYKGEPKIDLDRLSEIKNVVSIPLVLHGGSGIHDDIIK
                     EAIKRGIAKVNYATELRIAYSKGVKKVLNEDSEVIDPKKYGLAGLQSVKDFVKEKIKV
                     CGSVNRV"
     gene            complement(1055..2218)
                     /locus_tag="JAM15_17975"
     CDS             complement(1055..2218)
                     /locus_tag="JAM15_17975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAT6800134.1"
                     /translation="MFKLEEQKLKDLGAIITTNEIKQQPELWLETYEIYKSNKEKLNR
                     FIDTISNNHGQFRVIFTGAGTSAYIGNSILPYLKNKNDIRKYIFEAIPTTDIVSNPYD
                     YLKKDIPTLLISFARSGNSPESLAALNLGNKIVDNFYHLAITCNPQGELAKMTKNDEN
                     NYLLLMPSKSNDEGFAMTGSFSCMMLSAMLIFDSLEDDVEKSYINAIIEMGRNVIDRK
                     DEIHELINKDFDRVVYLGSGGLGGLTQEAQLKLLELTAGKISTVYDSPMGFRHGPKSF
                     IDENTLVFEFVSNCLYTRKYDLDVLEEIKRDKIAKFTCAVSVENENNFSGTKFEFKEK
                     YNKLPDVYLAMPYILFAQTIALFVSVKVGNKPDTPSATGTVNRVVKGVTIYEY"
     gene            2686..3603
                     /locus_tag="JAM15_17980"
     CDS             2686..3603
                     /locus_tag="JAM15_17980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAT6800135.1"
                     /translation="MKNIKMGMIGLGSIAQKAYLPILTKSERFEFVGAFTPNKVKREK
                     ICSDYRIMPFDSIESLAKKCNCIFLHSSTETHYEIIKILLNLGVHVYVDKPLASTVNQ
                     GEELIELSKKKNLNLMVGFNRRFCPMYKEIKNNATEIVSINICKHGLNSLRNVRFDST
                     LIDDYIHVIDTALWLANEDVEISGEDLFLTDNKNLIFVSHKLKGKHFSVNTSMHRDSG
                     TKLEQVEILSKGKIQRVKNLNVLEIEEGGNLTLKQSGAWVNILKQKGFEDISNHFIDC
                     IENNIKPAINGEECIKAQRLLEKIINSVK"
     gene            complement(3732..4661)
                     /gene="pfkB"
                     /locus_tag="JAM15_17985"
     CDS             complement(3732..4661)
                     /gene="pfkB"
                     /locus_tag="JAM15_17985"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HAT6800136.1"
                     /translation="MITVITFNPSIDRMYRVNNINIGEVQRVVSKNATAGGKGLNVAK
                     VCKILKENPLAMGFLGGFNGEFIKNELRKLDIQNKFTKIEQETRNCLNIIEDNKVSTE
                     FLEKGPLVEKSDLERFENDIEEVLKNTKILVASGSYCENMPIDYYEKIGNICRANNIK
                     FILDTSGEALKIALKSKPYLIKPNIDEIRHLLGINIESREEIILSGKKLIEMGAENVC
                     ISLGKDGMVYLNEYNVYDVKVPVVKCINTVGSGDSTVAGFSVGILRGYKIENLLKFAN
                     ACGISNALNMETGFVDLGEIDKYQDLVEVKKLS"
     gene            4930..5655
                     /locus_tag="JAM15_17990"
     CDS             4930..5655
                     /locus_tag="JAM15_17990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAT6800137.1"
                     /translation="MIKRNDKRPIYDQLVEILRTKIENEMEPNDRMLSERKICDEYGV
                     SRTTVRLAMAELEHMGYIYKRHGKGTFVAALSQNSQNLMESYSFTDYMRIQGKKPGTK
                     VLSFEVVESTKYFSEKLGITPGEKMIKIMRLRLADDLPMMLERTYLPMKEFIGLTKEK
                     IEQKPLYEIFREDYGEIIKVADEEFSAGIISDKEAKLLEVPGDSPCLKLLRTTYNDDN
                     IVIEFTLSVARSDKFVYRVRHVR"
     gene            5738..6892
                     /gene="nagA"
                     /locus_tag="JAM15_17995"
     CDS             5738..6892
                     /gene="nagA"
                     /locus_tag="JAM15_17995"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HAT6800138.1"
                     /translation="MKSFIYADKFFMKHGIKEKGYLSIINGKFGEFQQERPNITDNVI
                     DFSGKYIAPGLVDTHIHGLLGADVMDNTFEAINTISKGLLKYGVTSFLPTTLTDSVDT
                     LSDSVENISNSFNRVEGAKIQGIYLEGPFFTEKYKGAQNEKYFKDPDINILKLWQRKS
                     KNLIRKIAIAPERKGSIELTRYATKNNISVSLGHSSATFEQVKQVVNSGAKVFVHTYN
                     GMSPLNHREPGMVGAAMVLKDTYAELICDGHHVSPIAVKIMMDAKSSNNIALITDCMR
                     AGAMEDGKYTLGKFSVNVKNSVARLNSGSLAGSVLTMDKAVRNIVDWNIATLEDAIKM
                     ATYVPALSCNIDNVCGSIHQGMDADFIVTDKDFNIYETYISGICMYKVNK"
BASE COUNT         2521 a         1069 c          932 g         2651 t
ORIGIN      
        1 atattttaat tatatatgta atactttacc aataaaagct gatatttttc atcaattaaa
       61 tgaaaaaaat acaccattta catataatta atataaattt ttcatataac aaatatccta
      121 aacttatcta aaataaattt aggatatttt atttttatac tctatttaca gacccacaca
      181 ctttaatctt ttcttttaca aaatccttta ctgattgaag ccctgctaat ccatactttt
      241 tagggtctat aacctcagaa tcttcattta aaactttttt aaccccttta ctatatgcaa
      301 ttcttaattc agttgcatag ttaacttttg caatacctct ttttatagct tcttttataa
      361 tatcatcatg tattcctgaa cctccatgca atactaaagg tattgaaact acatttttaa
      421 tttctgataa tctatctaaa tctattttag gttcaccctt atacaatcca tgtgcagtac
      481 ctatagcaat agccaatgaa gatattcctg ttctatcgac aaactctttt gcctcttttg
      541 gatttgtata atcattacta ttcccgccat ctaaatcatc ttcttttcca ccaactttcc
      601 caagttctgc ttccactggt ataagagaag gactacatgc ttttactact gatttagata
      661 tagatatatt attttcaaag ctttcatgag aaccatctat cattattgat gtatatccac
      721 ttcttaaagc tttcattgca aggtcaaaac ttgaaccatg gtccagatgc attgctacag
      781 gtatctttac tctttctgca gcaacctttg catttgctag ataataatca agacctgcat
      841 attttacagt agatggagta gtttgtaata ttactggaga gtttaactcc tcagctgctt
      901 ctataacagc aattaccatt tccatatttt ctacattaaa tgctcctact gcatacccct
      961 catcttgtgc ctttttaagc attgatgttg ttgttactaa tgccacattg ataccctccc
     1021 aaattattta gttataatat tttaatctta tcttttaata ttcatatatt gttacacctt
     1081 ttactactct atttactgtt cctgtagctg atggcgtatc tggcttattt ccaaccttta
     1141 ccgatacaaa caatgctata gtttgtgcaa acaatatgta tggcattgca agatacacat
     1201 ctggtaattt attatacttt tctttaaact caaactttgt tcctgagaag ttattttcat
     1261 tttctactga cactgcacaa gtgaatttag caattttatc cctttttatc tcctctaaaa
     1321 catctaaatc atattttctt gtatataaac agttagatac aaattcaaat acaagtgtat
     1381 tttcatcaat aaatgatttt ggtccgtgtc taaaccccat aggagaatca tacaccgtag
     1441 atatttttcc tgctgtaagt tctaaaagtt ttagttgtgc ttcttgtgtc aaaccaccta
     1501 atcctcctga acctaaatat acaactctat cgaaatcttt atttattaac tcatgtattt
     1561 catcttttct atctataaca tttcttccca tttcaattat tgcatttata tatgactttt
     1621 ctacatcatc ttctaaacta tcgaatatta acatagcaga taacatcata cacgaaaaac
     1681 ttcctgtcat agcaaagcct tcatcatttg attttgatgg cattaataac aagtaattat
     1741 tttcgtcgtt tttagtcatt ttagctagtt ctccttgcgg attacaagtt atagctaaat
     1801 gataaaaatt atctacaatc ttattcccta aatttaaagc agccaaactt tcaggactat
     1861 ttccacttct tgcaaatgaa attaataatg ttggtatatc tttttttaag taatcatatg
     1921 ggtttgaaac tatatccgta gtaggtattg cttcaaatat gtattttctt atgtcatttt
     1981 tattcttaag gtaaggaagt attgaatttc ctatgtaagc tgaagttcca gcacctgtaa
     2041 atataactct aaactgccca tgattattac ttattgtatc tatgaatcta tttaattttt
     2101 ctttgttaga tttatatatt tcataagtct ctaaccataa ctcaggttgt tgttttattt
     2161 cattagttgt tattattgca cctaaatctt ttagtttttg ttcttctaat ttaaacattt
     2221 tcattctcct ttcatacttg taacgtttac atttggtaat gaggttataa ccactttaaa
     2281 ctataaaaaa atacactctt ttataatttt ttgcttagat tttttagtac tacttaaact
     2341 cactataaaa tatacgctat agattttaat taattttata gtttatcttt aaaaatttaa
     2401 taaaatcata ctttagtatt tttattttac gataaaaact tgttcagacc aaagtggtaa
     2461 ttaccactaa tccaaatata aattaattta aattttttgt caatacataa aatatttata
     2521 tcaatcaatt ttatagatat cctacaaaat tactttgtca atatttctta tttcgttaat
     2581 ttacttatat aagctttaaa tttatttttt gatacaaagt ttacaaattt atgtgtctga
     2641 attataatca attctgtaaa tataaaaacc ttaggagaaa gtattatgaa aaatataaaa
     2701 atgggaatga taggtcttgg ctccatagct caaaaggcat atttacctat attaactaag
     2761 tctgagagat ttgagtttgt aggagctttt actccaaata aagttaaaag ggaaaaaatc
     2821 tgtagtgatt atagaatcat gccattcgat tctattgaat ccctagctaa aaaatgtaat
     2881 tgtatttttc tacatagctc tacagaaaca cactacgaaa ttataaaaat attattaaat
     2941 ttaggtgttc atgtatatgt agacaagcct cttgcttcaa cagtaaatca aggagaagaa
     3001 cttatcgagt taagtaagaa aaaaaactta aatttaatgg ttggattcaa ccgtagattc
     3061 tgtcctatgt acaaagaaat taaaaataat gctacagaaa tcgtatctat caatatatgt
     3121 aaacatggat taaattcctt aagaaatgtt agattcgaca gtacccttat agatgactat
     3181 atacatgtta ttgacactgc tttatggtta gcaaatgaag atgttgaaat tagtggagaa
     3241 gatttatttt taacagacaa taagaatctt atatttgtaa gtcataaact taaaggtaaa
     3301 catttctctg taaacacctc tatgcataga gattctggaa caaagttaga acaagttgaa
     3361 attctttcaa aaggtaagat tcaaagagtt aagaatctta atgtactgga aatagaagaa
     3421 ggtggaaatc taactttaaa gcaaagtggt gcatgggtaa atatattaaa acaaaagggt
     3481 tttgaggata tatcaaatca ttttattgat tgtatagaaa ataatataaa accagctatt
     3541 aatggagaag agtgtatcaa ggctcaaaga ttactagaga aaattataaa ttcagtaaaa
     3601 tagatattta ttataaaaat aggttaaaaa tgaatttttc taacctattt ttatataaga
     3661 ctatatcttt tatattaaaa ttaaaatcta ttacaacaac attaaattta ttatattccc
     3721 attaaattta tttaacttaa cttttttact tcaactaaat cttgatattt atcaatttct
     3781 cccaaatcta caaatccagt ttccatattt aaagcattac ttataccgca agcatttgca
     3841 aatttaagta aattttctat tttataaccc cttaaaatac ctacactaaa tccagccact
     3901 gtgctatctc cactacctac agtatttata cactttacaa ctggtacttt tacatcatat
     3961 acattatatt cgtttaaata caccatacca tcttttccta aagatataca tacattctct
     4021 gcacccattt caataagttt ttttcctgac aagataattt cctctcttga ttctatattt
     4081 attcctaata aatgtcttat ttcatctata tttggcttta ttaaatatgg ttttgatttt
     4141 aaagctattt ttaatgcttc tcctgatgta tctaatataa attttatatt atttgctcta
     4201 catatatttc ctatcttttc ataataatct atcggcatat tctcacaata actaccagaa
     4261 gctactagta ttttagtatt ttttagtact tcctctatat cattttcaaa tctctctaaa
     4321 tcgctttttt ctactagtgg tcctttttct aaaaattctg tactaacttt attgtcctca
     4381 attatgttta agcaatttct agtttcctgc tctatttttg taaatttatt ttgtatatct
     4441 agttttctaa gttcattttt tataaattct ccattaaatc cgcctagaaa tcccatagct
     4501 aaaggatttt cttttaaaat tttacatacc ttagctacgt ttaatccttt acctccagca
     4561 gttgcattct tacttactac cctttgcacc tcacctatgt ttatattatt cactctatac
     4621 attctatcta tagatgggtt gaatgttatt actgtaatca tactagattc tcctcattat
     4681 taatttttac ttttctaaac aataaattaa tctgtaaaat aaaaaatacc tcatctataa
     4741 tatacccaaa gtggttatta ccaatttgaa tataaattat tttacttgtt ttgtcaatgt
     4801 accataattt tataataaat taataacctt acttattgaa ttttgattaa actttattca
     4861 ttgacataaa taattctata ttctataatc aaattgtggt aataaccact tagaaaggac
     4921 tatattttta tgataaaaag aaatgataaa agaccaatat atgaccagct tgttgagata
     4981 ttaagaacta agattgaaaa tgagatggaa ccaaacgata gaatgctttc tgaaagaaaa
     5041 atttgtgatg aatatggagt aagtagaacc acagttagac tagctatggc tgagttggaa
     5101 catatgggat atatatacaa aagacatgga aaaggaactt ttgttgctgc actaagtcaa
     5161 aattctcaaa acttaatgga aagttatagc tttacagatt atatgagaat acaaggaaaa
     5221 aagccaggta caaaggtatt atcatttgag gtagtagaaa gtacaaagta tttctctgaa
     5281 aaattaggta taactcctgg tgaaaaaatg ataaaaataa tgcgtttaag acttgctgat
     5341 gaccttccta tgatgcttga aagaacatat cttcctatga aagaatttat aggattgaca
     5401 aaagaaaaaa tcgaacaaaa acctttatat gaaatattta gagaagatta tggcgagatt
     5461 attaaagttg ctgatgaaga attttcagct ggaataatct ctgataagga agctaagtta
     5521 ttggaagtac caggagattc accttgtctg aaattacttc gtaccacata taatgatgac
     5581 aatatagtta ttgaatttac tttgagtgtt gctagaagcg ataaatttgt atatagagta
     5641 agacatgtaa gatagtgaat taaatagctt tcaagaaaat agaatgatat tataaacgtc
     5701 aatgccacaa tgatagtata attataagga ggttattttg aaaagtttta tttatgcaga
     5761 taaatttttt atgaaacatg gaatcaaaga aaaaggttac cttagtataa ttaatggcaa
     5821 attcggtgaa tttcaacaag aaagacctaa tattactgat aatgtcatag atttttcagg
     5881 taaatatatt gctcctggat tagttgatac tcacattcac ggtcttttag gtgcagatgt
     5941 catggacaat acatttgaag caataaacac aatttcaaaa ggcttattaa aatatggagt
     6001 aacatctttc ctacctacaa ctttaactga ttctgtagat acactaagtg attctgtaga
     6061 aaatataagc aatagcttca atcgagttga gggtgcaaaa atacaaggga tttatttaga
     6121 aggtccattt tttacagaaa aatataaggg cgctcaaaat gaaaaatatt ttaaagaccc
     6181 tgacatcaat atattaaaat tatggcaaag aaaatcgaaa aatttaataa gaaaaatagc
     6241 aattgctcca gaacgtaaag gttcaataga attaacaaga tatgcaacta aaaataatat
     6301 ctctgtttct cttggccata gttcagctac atttgaacaa gttaaacaag tcgttaattc
     6361 aggtgctaaa gtgtttgtac atacatataa tgggatgagc cctttaaatc atagagaacc
     6421 tggaatggtt ggggctgcta tggtactaaa agatacttat gctgaattaa tttgtgatgg
     6481 tcatcatgta agcccaatag ctgttaaaat aatgatggat gcgaagtcta gtaataacat
     6541 agctttaatt acagattgta tgagggctgg tgctatggag gatggaaaat atactcttgg
     6601 taagtttagt gtaaatgtaa aaaatagtgt tgcaagatta aatagtggga gtttagctgg
     6661 aagtgtatta actatggaca aggctgtgag aaatatagtt gattggaaca tagccacttt
     6721 agaagatgca ataaaaatgg ctacatatgt ccctgcttta agttgtaata ttgataatgt
     6781 ctgtggctcc atacatcaag gtatggatgc agactttata gtaacagata aggactttaa
     6841 tatatacgaa acttatataa gtggtatatg tatgtacaaa gttaataaat agattcaata
     6901 taaagttatg gaggcttcct aaaaatagag ataagtctct ttttcattgt taaaatgatg
     6961 aaaatacatt tgatttcata caaaaagagt gcctcataaa ctaaaaagtt aattttgaga
     7021 cactcctttt attaaggttc tttattttac aatataagtt tataaaatta agaatctgga
     7081 aatatttatg tgtattcttt gaataaaaat ttatttttta gtgataatta aacatttatt
     7141 ggtaaggcta tggctttaaa aatcatagcc tta
//
LOCUS       DACTZW010000135         7132 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.137, whole genome shotgun sequence.
ACCESSION   DACTZW010000135 DACTZW010000000
VERSION     DACTZW010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7132
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.137"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            170..3349
                     /locus_tag="JAM15_18000"
     CDS             170..3349
                     /locus_tag="JAM15_18000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAT6800139.1"
                     /translation="MKIDMIYKLIRRNTEPSRWSRGVKYYTNQLVDYIDIDIDDLQNN
                     LLTFRGGVNSEDNYSFYFNSITIDIKHFKIIENDCSCADCQSKGKSIFICKHIVAIVI
                     KSLKQIKNKRDVPPILIDILGADKDKLSNTNSKTSLDLSKQLLSLLDNTKRERVNLDV
                     LINVDSNKAIAEFKIGIDKMYILKNITEFAYSKLNGYELDFGKKFTYNPNIHYFADED
                     EKLVDIIEEYGTNLSYNFSSSHSKKFMEINASSLKQFLNAIKYKDFTLIFSKEEYHPK
                     ILNDTLPVRFDFKNIEDKIVLYSKDSLPVPLTKKNDVLLYDGNIYLLSHKKAHDYSKI
                     YQILSKTKELKFDKEDSKDVLGLLVPRLKSISQEVYLDDNIKNNITKDFKSEFYFDMI
                     DGNICCDVKYIYDDEDKKFVLPNIQKETTIENKLTSSQFTKENNHYVFKGTDYDLFTF
                     LDLQLESLKEFGDIYYSEKFKLKKIYNASSIQASINQTNQNYLEFNFNISDINPKEYK
                     DILKAFQEKRTFYKLKDGNFIDLSERETKDFFELVENLDIMDKSKNNKIYKNKALYIN
                     DVIRSKNLKFIDGKKELDSICEKFRNFDSINLEIPANLNANLRDYQINGLNWFKVLDY
                     YKFGGILADEMGLGKTIQTIAFLLSLSNKKSLIVTPTSLIYNWKNEFEKFAPDIKVLL
                     IHGNKRDREKCFMELENFDVILTTYGTLRNDLEKYSEIKFDYCILDEAQNIKNPVALV
                     TESVKSINAENKFALTGTPMENNLLELWSIFDFIMPGYLYSKAKFQELFINKEDNVKN
                     LKKLIKPFILRRSKKQVMKELPDKIEKNFFVELNKEQKKIYSVYSKDIQDKMKDKNLK
                     KDKIVIFSYLTKLRQLCLDPSIVVKDYNKKSSKIETCLEILRDSINENHKILLFSQFT
                     SVLKNISKELDKYKIKYHYIDGKTNAKERLELVDEFNNSMDKKVFLISLKAGGTGLNL
                     TSADMVIHFDPWWNPSVENQASDRAHRFGQKNSVQVIKLIAKGTIEEKIIKLQESKKE
                     LINQFINGELSNEGVLKSLSDEEIIDLFN"
     gene            complement(3634..4398)
                     /locus_tag="JAM15_18005"
     CDS             complement(3634..4398)
                     /locus_tag="JAM15_18005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAT6800140.1"
                     /translation="MAYFNYNDKQCYYNEIGDGTPLLFLHGNTASSKMFNDIIDFYKD
                     EYKVILIDFVGHGKSQMVDKFSADLWFDEAMQVICFLEAMNYKKVNIIGSSGGALVAL
                     NVALERPDLVNKVIADSFEGEVPLESFVQNVKIEREASKQDDGAKAFYIYNQGENWEK
                     VVDNDTEAIFEHYKTIGKFFHKPLETMQPEVLLTGSREDEFVSLISSDFFENTFSLLL
                     EKIKNGKMYLFDKGGHPAILSNGLDFSNVAKKFLEE"
     gene            complement(4635..6128)
                     /locus_tag="JAM15_18010"
     CDS             complement(4635..6128)
                     /locus_tag="JAM15_18010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAT6800141.1"
                     /translation="MKYTFEKFKLNEKILKSLKSLGYNIPSRVQREVIPKLLKGQNLV
                     VRSKTGSGKTASFAIPLCENINVDCNNIQALIVVPTRELALQVKDEISDIGRLKKVRC
                     SAIFGKQSIKDQIAELKQRVHIVVATPGRILDHINKGSIKLENVKYLVIDEADKMFNK
                     GFVEQMEKILLNLPKEKIVSLFSATIDEEIKYICEKYMLDYSVINIEENESDTNQKTR
                     QIDDKIIKANGREKYILLKELIYSENPKSVIIFCNTKEKVSKLYNKMSKEGFLIRELH
                     ADLSQERRIFVIKDFKNQKFNILVSSDVASRGIHIDDISLVINYDVPQDKENYIHRIG
                     RTGRKGNSGKAITIVTEKDEKYIENIETYIGYKINELKDIEKSRITHGKILFEEYSKG
                     ILKKVSKRKKVDKNSYKSKDIKLNIESEVVKLYLNAGKKKKIRVLDIVGAFSNIKGIT
                     NDDIGVIEVQDLCSYVDILNYKGDLILKKYKEIPIKKKMVKVKRDIR"
     gene            complement(6453..6995)
                     /locus_tag="JAM15_18015"
     CDS             complement(6453..6995)
                     /locus_tag="JAM15_18015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAT6800142.1"
                     /translation="MKICITVGHSILKGGKSTGVNGIVDEYNYNKKLAPMLAEMLISQ
                     GNTVDVIICPERHFMSEREEFFYRVPKVNSGKYDLLVELHLNKADGTQCGTEVLYYGT
                     EGLEYAKRVSNRLGELFENRGAKKRENLYILRNTNPVAIQIESFFCDNVNDCNKANES
                     GYDYIARLITEGILNKDINM"
BASE COUNT         2632 a          998 c          797 g         2705 t
ORIGIN      
        1 ttcatagttt ataagataat tcaataaaaa tctaatagta aattgttatt tacacatata
       61 ttgtaataga taaaagctat tcatatctgc cttaatttta gtcttaaatt tagagtgtaa
      121 attgaatgca tttagattat aatatataca gtgaggtaag gtgaataata tgaaaataga
      181 tatgatatat aaactaataa gaagaaatac agaaccatca agatggtcaa gaggtgtaaa
      241 atattatact aatcaattag ttgattatat agacatagat attgatgacc tacaaaataa
      301 cctgttgaca tttcgtggtg gagtcaattc tgaagataat tatagctttt attttaattc
      361 aataactata gatataaagc actttaagat aattgaaaat gattgtagtt gcgctgactg
      421 tcaatcaaag ggcaaaagta tttttatatg taagcatata gttgctattg tgataaaaag
      481 cttaaaacaa ataaaaaata aaagagatgt tcctcctatt ctaatagata tattaggtgc
      541 agataaggat aagctttcta atacaaattc taaaacaagc ttagatttaa gcaagcaatt
      601 actttctttg ttagacaata ctaaaagaga aagggttaat ttagatgtat tgataaatgt
      661 ggattcaaat aaagcaattg ctgaatttaa aataggaatt gataaaatgt acattttaaa
      721 aaacattact gaatttgcat attcaaaact taatggatat gaattagatt ttgggaagaa
      781 atttacttac aaccccaaca ttcattattt tgctgatgaa gatgagaagt tagtagatat
      841 tatagaagaa tatgggacaa atctttcata caacttttct tcatcacatt caaaaaaatt
      901 tatggagata aatgcaagct ctttaaaaca atttttaaat gctattaagt acaaggattt
      961 tacccttatt ttttctaaag aggaatatca tccaaagata ttaaatgata ctctacctgt
     1021 aaggtttgat tttaaaaata tagaagataa aatagtctta tattctaaag attcactacc
     1081 tgttccactt actaaaaaaa atgatgtact tttatatgat ggcaatatct atttattatc
     1141 acataaaaaa gctcatgatt attcaaaaat atatcaaata ttatcaaaga ctaaagagtt
     1201 aaaatttgat aaagaggatt ctaaggatgt tttaggattg ctagttccta gattaaaatc
     1261 tatatctcaa gaagtttatt tagatgataa cataaaaaat aatataacaa aagattttaa
     1321 atctgagttc tactttgata tgattgatgg caacatatgt tgtgatgtaa agtatatata
     1381 tgatgatgag gataaaaaat ttgtgctccc caacatacaa aaggaaacta ctattgaaaa
     1441 taaacttact tcttcacaat ttacaaagga aaataatcat tatgtgttta aaggaactga
     1501 ctatgaccta tttacatttt tagatttaca attagaatct ctaaaggaat ttggagatat
     1561 atattattct gagaagttta aattgaaaaa aatatataac gcttcatcaa ttcaagcttc
     1621 aatcaatcag actaaccaga attacctaga atttaatttt aatatatctg atataaatcc
     1681 aaaagagtac aaggatattt tgaaagcttt tcaagaaaaa cgtacttttt ataaacttaa
     1741 agatggaaac tttatagatt tatcagaaag agaaacaaaa gatttttttg aattagttga
     1801 aaatctagat ataatggata aatcaaaaaa taataaaatt tataaaaata aagctctata
     1861 tataaatgat gtaatacgta gtaaaaattt aaagtttata gatggtaaaa aagaactaga
     1921 cagtatatgt gaaaaattta gaaattttga tagcataaat ttagaaattc ccgcaaattt
     1981 aaatgcaaac cttcgtgatt atcaaataaa tggcctcaat tggtttaaag ttttagatta
     2041 ttataaattt ggtggtatat tagctgatga aatgggtctt ggtaaaacaa tacagactat
     2101 tgcattttta ttatcattat ctaataaaaa aagtcttatt gttacaccga catcactcat
     2161 ttataattgg aaaaatgaat ttgaaaagtt tgctccagat ataaaagttt tattgataca
     2221 tgggaataaa agagatagag aaaaatgttt tatggaatta gaaaattttg atgtaatact
     2281 tacaacatat ggtactctta gaaatgattt agaaaaatat agtgaaataa agtttgatta
     2341 ttgtatatta gatgaagctc aaaatataaa aaatccagta gctttagtaa ctgagtctgt
     2401 aaaaagtata aatgcagaaa ataaatttgc actcactggt acacctatgg aaaataatct
     2461 actagaatta tggtctatat ttgattttat aatgcctggc tatctatata gtaaagcaaa
     2521 gtttcaggaa ttgtttataa ataaagagga taatgttaaa aacctgaaaa aattaataaa
     2581 accttttatt cttagaagaa gtaaaaaaca agttatgaaa gaacttccag ataagattga
     2641 aaaaaacttt tttgttgaat tgaataaaga gcagaaaaag atatatagtg tatattcaaa
     2701 agatatacaa gataaaatga aagataaaaa tctaaagaaa gataaaatag ttatattttc
     2761 ttatttaact aaactaagac aactttgttt agacccaagt atagtagtaa aagattacaa
     2821 taaaaaaagt tcaaaaattg aaacatgttt agaaatactt agggatagta taaacgaaaa
     2881 ccacaaaata ttattgtttt cacaatttac ttctgtgctt aagaacataa gtaaggaact
     2941 tgataagtat aaaattaaat accattatat agatggtaaa actaatgcca aagaaagact
     3001 tgaacttgta gatgagttca ataatagtat ggataaaaaa gtttttttaa tatctttaaa
     3061 agcaggcgga actggtttaa atcttacatc tgctgacatg gtaattcact ttgacccatg
     3121 gtggaatcca tcagtagaaa atcaagctag tgatagagct catagatttg gtcaaaaaaa
     3181 ttcagtacaa gttataaaat tgattgctaa agggactata gaagaaaaaa taataaaatt
     3241 acaagaaagt aaaaaagagc ttataaatca atttataaat ggagaacttt ctaatgaagg
     3301 tgtattaaaa agtctatctg atgaagagat aatagactta tttaactaaa ttatttaatc
     3361 ctacagctta actatataaa tttattctaa catttatata gttaagctac aatatctgaa
     3421 taaataaaat ttcatattgt tatttaatcc caactttaca atctaatgat atctctttct
     3481 atacatattg catatacaaa tgtaataact tgactattag aatattttgt tttaacaatc
     3541 ctatttcatc ataataatga agtatatgta cactcacttt tgtaagtttt gcaatccatt
     3601 ttacagtttt cattattgta aattttggtt aaattattcc tctaaaaatt tctttgctac
     3661 atttgaaaaa tctaatccat tcgataaaat tgcaggatga ccacctttat caaacaaata
     3721 cattttacca tttttaatct tttcaagaag taatgaaaaa gtattttcaa aaaaatcact
     3781 agatattaga gatacaaact catcttctct acttcctgtt aaaagcacct ctggttgcat
     3841 agtttctaga ggcttatgaa aaaattttcc tatagtttta taatgttcaa aaatagcttc
     3901 tgtatcatta tctacaactt tttcccagtt ttctccttga ttataaatat aaaaagcttt
     3961 tgcaccatca tcttgctttg atgcctcacg ctctatttta acattttgta caaatgactc
     4021 taaaggaact tctccttcaa aactatctgc aattacctta ttcactaaat caggtctctc
     4081 aagtgcaaca tttaatgcaa caagagctcc tccactacta ccaattatgt ttactttttt
     4141 atagttcatt gcttctaaaa aacatatcac ttgcatagcc tcatcaaacc ataagtcagc
     4201 agaaaattta tcgaccattt gagattttcc atgacctaca aaatcaatta atattacttt
     4261 atattcatct ttataaaaat cgattatatc attaaacatt ttggaagagg ctgtatttcc
     4321 atgtaaaaaa agtaatggtg taccatcccc aatttcatta tagtagcact gtttgtcgtt
     4381 atagttaaaa tatgccatat attacctcct ttaatatccc tataggtata tatttattac
     4441 ttatatttaa aatgactatt gtcataaaca tttaaaaata gtatagctta gaatgtagat
     4501 aaagtcaaca ttcctttcct taacaacttc tattgttttt tgaaacttca tttcgataac
     4561 agaataattc ataaatattg atactcttac ttaaatatat gatttcatca tcagagagag
     4621 cagtaataac taaattatcg tatatctctt ttcactttaa ccattttttt ctttataggt
     4681 atctccttat atttttttaa tatcaaatct cccttataat ttaatatatc tacatatgaa
     4741 cataaatctt gaacttcaat tacacctata tcatcattag ttataccttt tatattacta
     4801 aatgcaccaa ctatatctaa aactcttatt ttcttcttct taccagcatt taaatataat
     4861 ttaacaactt cactttctat atttagtttt atatctttac ttttgtaaga atttttatca
     4921 actttttttc tctttgatac tttttttagg attccttttg aatattcttc aaacaaaatt
     4981 ttgccatgtg taattctact tttttctata tcttttaatt catttatttt atatcctata
     5041 tacgtttcta tattctctat atatttttca tccttttcag ttactatagt aattgccttt
     5101 ccactatttc cttttctccc agttctacct attctatgta tatagttttc tttatcttgt
     5161 ggcacatcat aatttattac taaagaaata tcatcaatat gtattcctct ggacgctaca
     5221 tcactactaa ctaatatatt aaatttttgg tttttaaaat ccttaattac aaaaattctt
     5281 ctttcttgtg ataaatctgc atgtaactct cttattaaaa aaccctcttt actcatctta
     5341 ttatataatt tagatacttt ctctttggta ttacaaaata ttatcacact ctttggattt
     5401 tcgctgtata ttaattcttt taaaaggatg tacttctctc ttccatttgc cttgattatt
     5461 ttgtcatcta tttgtcttgt tttttgatta gtatcgctct cattttcttc tatatttata
     5521 acactgtaat ctagcatata tttttcacat atatatttta tctcttcatc tattgtagct
     5581 gaaaaaagac ttactatttt ctccttaggt aaatttaata atattttttc catttgttca
     5641 acaaaacctt tattaaacat tttatctgcc tcatctatta ctaaatactt tacattttcc
     5701 aacttaatag aacctttatt tatatggtca agtattctgc ctggagtagc tacaacaata
     5761 tgaacccttt gtttcaattc agctatttgg tcttttatag attgtttgcc aaatatagca
     5821 ctacatctca ccttctttag tctccctata tctgatatct catcttttac ttgcaaggct
     5881 aattctcttg ttggaaccac tataagagct tgaatattat tgcaatctac atttatattc
     5941 tcgcataaag gtattgcaaa acttgctgtc tttccacttc ctgtttttga cctaactact
     6001 aagttttgac cttttaataa ttttggaata acttctcttt gtactctaga aggtatatta
     6061 tatcctaaac tcttcaatga cttaagtatc ttttcattta acttaaattt ttcaaatgta
     6121 tatttcatat attaccacct tattatattt atcttatcta tatatttttc tacattatat
     6181 tattataata caaggttcta ctatttttat attatttatt agactgaaga taaaaatata
     6241 tactctataa acctatagtt tagtagcaaa tcaattaaat ttttatattt aaatacctcc
     6301 ttaaatatac tgataaatca atatttagga ggtatctctt gtcaataatc aaactaatct
     6361 atattttgaa agtttaaatt atactaatac attgtatttt tatttatatc taatattaaa
     6421 aggtattaat caatacctaa atcaccataa tctcacatat ttatatcttt attcaatata
     6481 ccttctgtaa tcaatcgtgc tatataatca taacctgatt catttgcttt gttacaatca
     6541 ttcacattat cacagaaaaa actttcaatc tgtattgcaa ctggatttgt atttctcaat
     6601 atatataaat tttctctttt tttagctcct ctattttcaa ataattctcc aagtctatta
     6661 gatactcttt tagcatattc taatccttca gtgccatagt aaagcacttc tgtaccacat
     6721 tgtgttccat cagctttatt taaatgtagc tctactaata aatcgtattt accactgttt
     6781 acttttggaa ctctatagaa aaattcttct ctttctgaca taaagtgcct ttctggacaa
     6841 attattacat ctactgtatt accttgactt ataagcatct cagctaacat aggagctaat
     6901 tttttattat aattgtattc atcaactata ccatttacac ctgtactttt accacctttt
     6961 agtatactat gacctactgt tatgcatatt ttcatttact tttttcacct tcttttaagc
     7021 caatttttat ataatagtaa tataatttta aagttattac taataataat atattaattg
     7081 aagaaggtaa aagttctccg tgattatcat ttttttaaca tatttgtctt at
//
LOCUS       DACTZW010000136         6895 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.138, whole genome shotgun sequence.
ACCESSION   DACTZW010000136 DACTZW010000000
VERSION     DACTZW010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6895
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.138"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(119..727)
                     /locus_tag="JAM15_18020"
     CDS             complement(119..727)
                     /locus_tag="JAM15_18020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HAT6800143.1"
                     /translation="MEKDFFRKNGIDLAKSILGKYLIRKYENKVIVTKIIETEAYMGV
                     NDKGAHVYGNKKTDRTKPLYLDGGHIYVYLIYGMYNCLNLSANIENVPECVLIRGVEP
                     ITSLDEISMNRYNKAYTELSKYQVKNITNGPGKLCKALKIDRSLNSKSIMGEELYISD
                     FYYDDKGKKVFSKDELDIKTSKRINIDYAEEAKDFLWRFYIE"
     gene            complement(836..3574)
                     /locus_tag="JAM15_18025"
     CDS             complement(836..3574)
                     /locus_tag="JAM15_18025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing sensor histidine kinase"
                     /protein_id="HAT6800144.1"
                     /translation="MESKGTLSKNKVYILANGLFLVIALLNINLYTVSINMYRIILLW
                     IFGYSIVYISSFKTDEFINILKVGCLVLVFVSILGVVNLKIQKFQIVLLNLSIINMST
                     FIYLTISKVKKLRISPILIFYSAFVILDYFIRNIFSDINWNIIIVLINVCISMFNLLY
                     LLNKLDSNIEHYKLIKDLTYFVFFTTIICFVAISKINIVDSDRLIGVIYLLLCNHTYY
                     VYVYSLNNRVVYPYYELDSINKKLSKKSEQLGKINLAIEKDMIIQRTLKNYIDQRKEL
                     LRQALDTIPNVWIVTDYDFNISYTNNKFKDEFSKDMNNYYKILTFIKEDEKVAEKLKK
                     FDNDISIIDKLVELNDKIYLLSLSNNKDESNYLISLNDITNEIKIDEEIRNINKDYEN
                     IILNIPSPILVRSAEGGIKKNKVISINKKYEKSFKCVSSDLVDMTLEQYFETFNIDFF
                     DNRKFKRLNLTQEKKAEIVSYNDTANCIVNFVMSDSEGEEHVEEVRVGDYWSDNKLFK
                     LLTFRDITKEINILRTVNEQKIIYEKLLDVIPEAIFLEDLSTSRVLYTNRAFRELFGI
                     SSDVLGVTTQKYRNILVKKYINNLNIGEREKSIHIVNENNHIKEVKMISRTLYFGQKR
                     SRVRIIKDLSVQRESERLKKALIKQRQYDQMKMEFYANISHELKTPLNNIYSSVQLIE
                     NLYKKGKIIDFQDILKEHIKITKQNMFRLLRLIDNIINISQVKSDIYKIKAVNFDIID
                     ITERIVTSISSYAKSKGIDLIFDTDEETVMVGLDPESIERIILNILSNAIKFTLEGGE
                     ILVGIYKKDETVEIIIKDTGVGIDKEKLNDIFNRFKQIENSGISNEFGSGIGLCLTKS
                     LIEIQNGKIYIDSKVGEGTSVKIIFPIKEVVEEVYDNSNYNDNIEKFEIEFFDIYK"
     gene            complement(3722..4513)
                     /locus_tag="JAM15_18030"
     CDS             complement(3722..4513)
                     /locus_tag="JAM15_18030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002844893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HAT6800145.1"
                     /translation="MKLKKLLSVALVSAIAISAVGCSNKEDKKILVGASSNPHAKILE
                     VAKPLLKEKGYDLEVKIFDDYVLPNTALDEGSLDANFFQHIPFLEETVKEKGYKLTYT
                     SKVHIEPMGFYSEKVKSLDELKDGAVIAVPNDATNGARALKLLAKNKLIELKDGELIT
                     KKDITKNPKNIVIKEMNAEQLPTVLKDVDGAVINSNYALTANLNPTKDAIVIESSDSP
                     YVNIIACRENNKDSDKIKALSEAMNSKEVKKFIQDEYKGSIVPAF"
     gene            complement(4549..5205)
                     /locus_tag="JAM15_18035"
     CDS             complement(4549..5205)
                     /locus_tag="JAM15_18035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6800146.1"
                     /translation="MNSLIDFLTTLFPNALLQTLYMVIVPTIVATILGFILAIILVVT
                     KPDGLKPNSTINSALGFIVNIFRSFPFMILIVAMIPITRLIVGTSIGETAAIVPITIG
                     AAPFIARIIESSLNEVDKGLIEAAKSFGATKRQIVFKVMIKEAMPSIVSGITLSIISI
                     LGYTAMAGAVGAGGLGNIALIYGYQRFDTAVMVYTVIALIILVQIIQGVGNLAYKKLK
                     "
     gene            complement(5198..6163)
                     /locus_tag="JAM15_18040"
     CDS             complement(5198..6163)
                     /locus_tag="JAM15_18040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002844318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HAT6800147.1"
                     /translation="MISIKNVNKYYGKIQVLKDVSIEIESGEIFGIIGHSGAGKSTLL
                     RCINGLEEYQEGSVLVSDKEVKSLNEKQMRDLRKELGMIFQHFSLLERKTVFDNVALP
                     LECFGYSKAEIKKRVLELLEVVGISEKKNDKPRNLSGGQKQRVAIARALALNPQVLLC
                     DEATSALDPNTTKSILSLLEDINKKLGITIIVVTHQMEVIKQICGRVAIMENGEVLEV
                     GDTEEIFLRNTKGLRKLIGEESIILPKGTNIKILFPKDISNEAIITTMARELNIDVSI
                     IFGKLEQFKDDILGSLIINISDKSGEQVKQYLTSKGIRWEEMINE"
     regulatory      complement(6269..6375)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
BASE COUNT         2196 a         1158 c          629 g         2912 t
ORIGIN      
        1 ttaaatatgt ttgtaattct ataaagttat ttttatcaaa ctaaaaattc tataaaaaaa
       61 taagatacat acctataaaa taccttccta tagatacata tcttacctat ataaaaactt
      121 attctatata aaaacgccat aaaaaatctt ttgcttcttc tgcataatct atatttatac
      181 gtttactagt ttttatatct aactcatctt tactaaatac tttttttcct ttatcatcat
      241 aataaaaatc acttatatat aattcttcac ccattatact cttactattt agacttctat
      301 ctatttttaa agctttgcaa agttttcctg gtccgttagt aatatttttt acttgatatt
      361 tactcaactc agtgtaagct ttgttgtatc tattcataga tatctcatct aaagaagtta
      421 taggctctac ccctcttatt aatacacact ctggcacatt ttctatattt gcagataaat
      481 ttaagcaatt atacatacca taaattaaat aaacatatat atgtccacca tctaaatata
      541 atggcttagt tctatctgtc tttttattgc catatacatg tgctccttta tcatttacac
      601 ccatgtatgc ttctgtctct atgattttgg taacaattac tttattttca tatttcctta
      661 ttagatattt acctaatatt gatttggcta gatcaattcc attttttcta aaaaaatcct
      721 tttccaaaat ttcacctcat aaaatttatt taaaacgcat caaataaaac taaagtaata
      781 aataaaatta actcttatta atgtgatata tataaacaat aaatttagac atttattatt
      841 tatatatatc aaaaaattct atctcaaact tttcaatatt atcattgtaa tttgaattat
      901 catatacttc ttcaacaacc tctttaattg ggaatataat ttttacacta gttccttctc
      961 ctaccttact atctatgtaa atcttcccat tttgaatttc aatcaatgat tttgtaaggc
     1021 ataaacctat accacttcca aattcatttg atataccact gttttcaatt tgtttaaatc
     1081 gattaaatat atcatttaat ttttctttgt ctatgcccac tccagtatct tttataatta
     1141 tctctactgt ttcatctttt ttatatatac ctacaaggat ttctcctcct tctaaagtaa
     1201 attttatagc atttgataat atatttagta ttattctttc tatagattct gggtcaagcc
     1261 ctaccataac agtttcttca tccgtatcaa aaattaaatc tattccttta gacttagcat
     1321 aactactaat agatgtaact attctttctg ttatgtcaat aatatcaaaa ttaactgctt
     1381 taatcttata tatgtctgac ttaacttgag aaatatttat tatattatct attaatctca
     1441 ataatctaaa catattttgt ttagttattt ttatatgttc ttttagtata tcctgaaaat
     1501 caattatttt tcctttttta taaaggtttt caataagttg aactgaacta tatatattat
     1561 ttaaaggtgt cttaagttca tgagatatat tagcataaaa ctccatcttc atttggtcat
     1621 actgtctttg ttttattaat gcttttttaa gtctttcaga ctctctttgc acacttaaat
     1681 ctttaataat tctcactcta cttcttttct gtccaaagta taatgttctt gatatcattt
     1741 ttacttcttt aatgtgatta ttttcattta ctatatggat actcttctct ctttctccta
     1801 tatttaaatt gtttatgtat ttttttacta atatatttct atatttttgt gttgtaactc
     1861 ctaatacatc actagaaatt ccgaacaact ctctaaaagc tctatttgta tatagtactc
     1921 ttgatgtact taaatcctca agaaaaatag cctctggtat aacatcaagt aatttttcat
     1981 atattatttt ttgttcattt actgttctaa gaatatttat ctctttagtt atatctctaa
     2041 atgtaagcaa tttaaagagt ttattatctg accaatagtc tccaactcta acttcttcaa
     2101 catgttcttc accttctgag tcagacatca caaaattaac tatacagttt gctgtgtcat
     2161 tgtaacttac tatttcagct ttcttttctt gtgttagatt taatctttta aatttcctat
     2221 tgtcaaagaa atctatgtta aaagtttcaa aatattgttc taatgtcata tcgactaaat
     2281 cacttgaaac acatttaaaa ctcttttcat attttttatt tatacttatt accttattct
     2341 tctttatacc accttcagca cttcttacaa gtataggaga tggaatattt agtataatgt
     2401 tttcatagtc tttatttata tttcttattt cttcatctat tttgatttca tttgtaatat
     2461 catttaaact tattaagtaa ttgctttcat ctttattatt acttaaactt aacaaataaa
     2521 ttttatcatt taactctacc agtttatcaa ttatacttat atcgttatca aatttcttca
     2581 atttttcagc aactttttca tcttccttta taaaagttaa tattttataa taattattca
     2641 tatcctttga aaattcatct ttaaatttat tatttgtgta acttatatta aaatcatagt
     2701 ctgttactat ccatacattt ggtattgtat ccagagcttg tctaagtaat tcttttctct
     2761 ggtctatgta gttttttaat gttctttgta taatcatatc cttttctatt gctaaattta
     2821 tctttcctaa ttgctctgac tttttactta attttttatt gattgaatca agttcataat
     2881 atggatacac tactctatta ttaagactgt atacatatac ataataagta tggttacata
     2941 atagtaaata tattactcct attaatctat ctgaatctac tatattaatc ttagaaattg
     3001 ctacaaaaca tataatagtt gtaaaaaaaa caaaatatgt taaatctttt attaacttat
     3061 agtgctcaat gttactatca agtttattca acaaatatag taaattaaac atagatatac
     3121 aaacattaat taatacaata attatattcc agttaatatc actaaaaata tttcttataa
     3181 agtaatctaa tatcacaaaa gcactataaa aaattagtat tgggcttatt cttagttttt
     3241 ttactttaga aatggttaag tatataaaag tagacatatt aattatgctt aagttaagca
     3301 atacaatttg gaatttttga atttttaaat ttactactcc taaaatgctt acaaaaacta
     3361 atacaaggca ccctactttc aatatattta taaattcatc tgttttaaag ctacttatat
     3421 aaactataga atatccaaat atccaaagta aaattattct atacatattt atagaaactg
     3481 tatacaaatt tatatttaaa agtgcaataa ccaaaaataa cccattagct agtatataga
     3541 ccttattctt acttaaagtt cctttagatt ccatattccc caccacttct tcatttttat
     3601 atagttttac ctataaatat gttaccacaa ttcttccaaa aaatttgtca ctttctagtt
     3661 ataaaaaaaa atgagtaaat atttttaatt ttactcattt tgtagatttt gtatattcag
     3721 tttaaaaagc tggaactata cttcctttat attcatcttg tataaatttt ttaacttctt
     3781 tactattcat agcctctgat aaagccttaa tcttatcact atctttatta ttttctctac
     3841 aagctattat atttacatat ggagaatcac ttgattctat tactattgca tccttagtag
     3901 gatttaggtt agctgttaaa gcgtaattag aatttattac tgctccgtca acatctttta
     3961 atactgttgg taattgctct gcattcattt cttttattac tatattttta ggatttttag
     4021 ttatatcttt tttagttata agctctccat cttttaattc tatcaattta ttttttgcta
     4081 ataatttaag tgctctagct ccattagttg catcatttgg cacagctata acagctccat
     4141 cttttaattc atctaatgac ttaacttttt ctgaatagaa tcccattggc tctatatgaa
     4201 ctttagatgt ataagtaagt ttatatcctt tctccttcac agtttcctct aaaaatggaa
     4261 tatgttgaaa gaagttagca tccaaagacc cttcatctaa agctgtattt ggaagtacat
     4321 aatcatcaaa tatttttact tctaaatcat atcctttttc ttttaacaaa ggttttgcaa
     4381 cttccaatat ctttgcatgt ggatttgatg aagctcctac tagtattttt ttatcctctt
     4441 tgtttgaaca acctactgct gatattgcta ttgctgacac caatgctact gataataatt
     4501 tctttaattt catttttact ccccctcttt aaaatgttta taattaattt attttagttt
     4561 cttataagcc agatttccta ctccctggat tatctgaact aatattataa gtgctattac
     4621 agtatatacc attactgctg tatcaaatct ttgatatcca taaataagtg ctatattacc
     4681 taatcctcca gctcctactg cacctgccat agctgtataa ccaagtatag atattattga
     4741 taatgtaatt ccagatacta ttgaaggcat agcttccttt atcataactt taaatactat
     4801 ttgtcttttt gtagctccaa aagattttgc tgcttctatc aatcctttat caacttcatt
     4861 taatgagctt tctataattc tagcgataaa cggtgctgcc ccaatagtta ttggcactat
     4921 tgcagcagtt tcccctatac ttgttccaac gattaatcta gttattggaa tcattgcaac
     4981 tataagtatc ataaatggga aacttctaaa tatatttact ataaatccta atgcactatt
     5041 tattgtgcta tttggtttta atccatctgg ttttgtaact actaatatga ttgctaatat
     5101 aaatcctaat attgttgcca ctatagttgg tactataacc atatacaaag tttgtaacaa
     5161 tgcatttgga aatagtgttg ttaaaaagtc aattaaacta ttcatttatc atttcctccc
     5221 atcttatgcc cttactagtt agatattgtt ttacttgctc tccactttta tctgaaatgt
     5281 ttataataag tgaacctaaa atatcatctt taaattgttc taatttccca aatattatag
     5341 acacatctat atttagttct cttgccatag tcgtaataat agcttcatta gaaatatctt
     5401 tagggaatag tatctttata tttgttcctt ttggcaatat tatactttct tcacctatta
     5461 attttctaag tcctttagta tttcttaaga atatttcttc tgtatctcct acctctaata
     5521 cttctccatt ttccattatt gctactcttc cacaaatctg ctttataact tccatttgat
     5581 gagttacaac tattattgtt attcccaatt ttttatttat atcttcaagc aatgaaagaa
     5641 ttgactttgt agtatttggg tctaatgctg aagttgcttc atcacaaaga agtacttgtg
     5701 ggtttagtgc taaagctcta gcaattgcaa ccctttgttt ttgtccgcca cttagatttc
     5761 tgggtttatc atttttcttt tcagatattc caactacttc taataactct aaaactcttt
     5821 ttttaatttc tgcctttgag tatccaaaac attctaatgg caatgctaca ttatcaaata
     5881 cagtttttct ttcaagcaat gaaaagtgtt gaaaaatcat tcctaactct tttcttaaat
     5941 ccctcatttg cttttcattc aatgacttta cttctttatc agaaacaagt acactgcctt
     6001 cttggtattc ttctaatccg tttatacatc tcagtagtgt tgatttccct gcaccactat
     6061 gacctattat tccaaaaatt tctccagatt ctatttcaat acttacatct ttaagcactt
     6121 gaatctttcc ataatactta ttaacatttt ttatgctaat cataaaattt cctcccatat
     6181 attctgctca gtttttatgt ttatcctctc ttatgtatta caacaaaata aaagcccgag
     6241 tataaactca ggcttagaaa gctatttata ctcatctatc aactatatta gttgcaggat
     6301 ttagcaccaa tgtatataaa atatactggt tgccgggttt caaagggcca gtccctccac
     6361 cactcttgat aagacgttat ttaatttaat tctattatca tttgttgcta tgttatatat
     6421 gatatattca ttaatagtat ttgtcaataa atttatttaa attttttatt ttttattatc
     6481 gttaattaac tatttttaat tagttttcta gctcctaaca ctttatattt taatgtctat
     6541 ataactatag aacatcatta taagaaataa attaaataac atcaatctat ctaaatcatc
     6601 tgtaaagtaa attaagaaaa ttaacatttt atccaaactc tatcctacta ttaaataaaa
     6661 taatttaaat acaatgatga ttatatagct ctagtacttt agactttctg aacctcccat
     6721 gactaaagtc acagggttcc tgcttcatag aattttgcat actaaaatat gtcttactaa
     6781 ttctccacag gccatcccca tagttcctac ggttcttaca taagttattt attttgaatt
     6841 gttattagtc ttaatccttc ttttaatata tttatacttg catttatatc tctat
//
LOCUS       DACTZW010000137         6879 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.139, whole genome shotgun sequence.
ACCESSION   DACTZW010000137 DACTZW010000000
VERSION     DACTZW010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6879)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6879)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6879
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.139"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            <1..588
                     /locus_tag="JAM15_18045"
     CDS             <1..588
                     /locus_tag="JAM15_18045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAT6800148.1"
                     /translation="KKIFSGQYNTLSVSSGIALTAAVLSIVIKEWMYWYTRSAAKHTN
                     SDALMADAWHHRSDALSSVGSLIGILGARLGYAILDPIASVVICGCILKAALDIFKES
                     INKMVDHSCDNATETKIREVVLQQQGVDGIDELKTRMFGAKMYVDIEILADGNLALYD
                     AHRIAEGVHQTIENNFPQCKHCMVHVNTNELLYST"
     gene            1070..1696
                     /locus_tag="JAM15_18050"
     CDS             1070..1696
                     /locus_tag="JAM15_18050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAT6800149.1"
                     /translation="MSDTKENILKIALHLFAVNGYEAVSVSMIAEALGMTKGALYKHY
                     KNKQDIFDCIVERMYQIDNKRAKEYQVPESTIVVTPNAYRNTTIESLTTFTFAQYDFW
                     VTDEFASNFRKMLILEQYRNLKMNMLYQKCLVNGAISYIEDIFNEMVEKGVLQECDTK
                     QLAIEYYAPLFLLISVADAVENCWDLKSQLTTHVNQFVKKYITNEKVK"
     gene            1818..2534
                     /locus_tag="JAM15_18055"
     CDS             1818..2534
                     /locus_tag="JAM15_18055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAT6800150.1"
                     /translation="MEYIRSKKYFTPDLQAKIMGPNPIKLQEELLQNHKIPSGSYVCD
                     LGSGQGLTSVFLAKEYGFVVFAVDLWSEPKENEEFFKKMGLSSAQIKSVKADANELKF
                     EKEFFDAVVSTDSYNYFGRDPIYLDEKLLPFVKKGGFIYITVPGMKKDCHDKLPEELL
                     LSWTPEELDYLHDITYWSNIISHCKKADLISIYEMESNSEVWSDWIKQNNEYAINDRK
                     AIEAGGGDYLNFIAIILQKK"
     gene            2684..2875
                     /locus_tag="JAM15_18060"
     CDS             2684..2875
                     /locus_tag="JAM15_18060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003064779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
                     /protein_id="HAT6800151.1"
                     /translation="MKKYEYVEINYNAKGVVFLCTDKHKEIIDSYAKTGYHYAGFVPT
                     EIDAKGCMRKIDLIFEKED"
     gene            2899..3129
                     /locus_tag="JAM15_18065"
     CDS             2899..3129
                     /locus_tag="JAM15_18065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800152.1"
                     /translation="MIGLKRRDMNYIMKVGAKAQGVSVSEFRAMLQYTIDKTMESTDP
                     DVQANFKRYFGNKRPTPEEYIHTITKKTKVKV"
     gene            3396..3815
                     /locus_tag="JAM15_18070"
     CDS             3396..3815
                     /locus_tag="JAM15_18070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006354941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAT6800153.1"
                     /translation="MKPSDFQKTIQCQFECKLKKIVKGIIWNYRKELKRRKNKEISFS
                     ELPDITVESLATWDDYETNYTIFNVCGIDIKVLDDELAEALKQLPEKKRNNVLMYYFL
                     EMSDTEIADIMNYTRGAVFKHRHRALETMKEILKEKK"
     gene            3818..4072
                     /locus_tag="JAM15_18075"
     CDS             3818..4072
                     /locus_tag="JAM15_18075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAT6800154.1"
                     /translation="MKKKYKHPSYYLISSAMDGDETAIEKLLAFYDPYISKCCLRPLY
                     DEYGNVYIVVDMELKGRIREALIKMILDFEIDIDIETEEE"
     gene            4447..4650
                     /locus_tag="JAM15_18080"
     CDS             4447..4650
                     /locus_tag="JAM15_18080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HAT6800155.1"
                     /translation="MNNTDVPIWEKYTLSIEEASRYFRIGEKKLRRLAEENLDSGWVI
                     VNGNRIQIKRKQFEKIIDTLDEI"
     gene            4728..5918
                     /locus_tag="JAM15_18085"
     CDS             4728..5918
                     /locus_tag="JAM15_18085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006354938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAT6800156.1"
                     /translation="MSKMKRQDSKGRNLRLGESQRKDGRYVYKYTDIFGKPQFVYAWK
                     LVPTDKTPVGKRDDISLREKEKQIKKDLDDGIDTVGGKMTVCQLYEKKNNQRKNIKRN
                     TKIGRQYLMNALENDPLGMRAIDTVKQSDAKEWAIRMNDKGYSYKTIDNYKRSLKASF
                     YMAIQDDCIRKNPFNFKLSDVLEDDTEAKVILTPEQEEKLLAFMETDNVYSKYRDEVI
                     LLLETGLRISELCGLTTHIDMLNRVINIDHQLLRNTEVGYYISTPKTKNGKRELPLTE
                     RAYQALERILKNRGKAQPLVVDGYSNFLFLNREGLPKVAGNYESMVRGLIKKYNKTYK
                     DKLPNITPHSFRHTYCTNMANKGMNPNTLQYIMGHANITMTLGYYAHGTFQSAKAELE
                     RLAS"
     gene            complement(6538..>6879)
                     /locus_tag="JAM15_18090"
     CDS             complement(6538..>6879)
                     /locus_tag="JAM15_18090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800157.1"
                     /translation="MNSNMGMPNNMPNNMNSNMGMPNNVPNNMNSNMGYNMNNTMGIP
                     NFSCNQNMPPNVLMMIPGVICHNTMQGMPVVMPSTMPPNIYPTPYGSSNMSIQGIPQA
                     TNIEEFDEEEM"
BASE COUNT         2435 a         1056 c         1366 g         2022 t
ORIGIN      
        1 aagaaaatct tttcgggaca gtacaatacg ctttctgtct ctagtggaat cgcacttacg
       61 gcggcagtct tatccattgt tataaaagag tggatgtact ggtatacaag aagtgctgca
      121 aagcatacaa attctgacgc acttatggct gacgcatggc atcaccgctc tgatgcactc
      181 tcgtcggttg gttccttaat tggcatttta ggagcacgtt taggctatgc tattctcgac
      241 cctattgcaa gcgttgtgat ttgcggttgt atcttaaaag ctgctttgga tattttcaaa
      301 gaaagcatta acaaaatggt agaccatagt tgtgacaatg ctactgaaac aaagattagg
      361 gaagttgtgc ttcagcagca aggggttgat ggtattgatg aattaaaaac ccgcatgttc
      421 ggagcgaaaa tgtatgtaga tattgaaata ttagctgatg gtaatttagc tctttatgac
      481 gctcatagaa ttgctgaggg agtccatcaa acgattgaaa acaactttcc acaatgtaaa
      541 cattgtatgg tacatgttaa tacgaatgaa cttctctatt ctacatagga cagggaagat
      601 gatttaagac tattgaaagg gaaagggggg aagtaggtta tggaacaata ctggtggatt
      661 atcattgttg tggttttgat tgtcgttggc ttacttaaaa ttgtaattat gaagaagtat
      721 aaccaaagga gaaattctaa caatcgttca aaagatagcg aggacgacaa gatgtattaa
      781 gatttattga aatctgttat gctgtagaat gatgttttta gatactagaa agtgctttaa
      841 gggggctaac gttatggaaa gctttgagta caattctttc caatcaacag tattttgcat
      901 agagaagtgt atgtaggaaa tatggtgcaa ggcataaagc accagcgatc gagagatcaa
      961 cctatgaacc aaaggcacac tacattttat accacttgac aagtaaacga gcgcttacta
     1021 taatggttta cagaagtaaa cgttcgttta ctaaagaagg aggttgtaaa tgtctgacac
     1081 aaaagaaaat atattaaaaa ttgcactaca cttatttgca gtgaatggtt atgaggctgt
     1141 ttctgttagt atgattgcgg aagccttggg aatgacaaaa ggagcattat ataaacatta
     1201 taaaaataag caagatattt ttgactgtat cgtagaacgt atgtatcaaa ttgataataa
     1261 gcgagctaag gaatatcaag taccagaaag cacaatagtg gtaaccccta atgcatacag
     1321 aaatacaact attgaaagtc taacaacatt tacttttgca caatacgatt tttgggtgac
     1381 tgatgaattt gcgtctaatt ttcgcaaaat gttaatacta gagcaatata gaaatttaaa
     1441 aatgaatatg ctttatcaaa aatgtcttgt aaatggtgct atcagttata tagaagatat
     1501 atttaatgaa atggttgaaa aaggtgttct tcaagagtgt gatacaaagc aacttgctat
     1561 tgaatattat gcgccattat ttctgttgat aagtgtagca gacgcagttg aaaattgttg
     1621 ggatttaaaa tctcaattaa ccacacacgt taatcaattt gttaagaaat atattacaaa
     1681 tgagaaagta aaataatcct ttattctatc ctgaatacaa acataacttt ttaatttcag
     1741 cagagaaaca caaaatgaat attgttataa gtcacaaata ttaactatta aaatattaca
     1801 ataatggaga tgagaaaatg gaatatattc gcagtaaaaa atattttaca cccgacttac
     1861 aggcaaaaat tatgggaccg aatcctataa aattacaaga ggaactatta caaaatcata
     1921 aaatcccgtc tggtagctat gtctgtgacc ttggaagtgg acaaggttta acttctgtat
     1981 ttcttgcaaa agaatatgga tttgttgttt ttgcagttga cttatggagt gagccaaaag
     2041 aaaatgaaga atttttcaaa aaaatgggat tatcttctgc acaaattaaa tccgtaaaag
     2101 ctgacgctaa tgaacttaaa tttgagaaag aattttttga cgctgtagta agtacagatt
     2161 catataatta ttttggacgt gaccctatat atttagatga aaaattactt ccatttgtta
     2221 aaaaaggcgg gtttatttat atcacagttc ctggtatgaa gaaagattgc catgacaaac
     2281 ttccagaaga gttattgtta tcatggacac cagaggaact tgattatcta catgatataa
     2341 catattggtc taacataatt agtcattgta aaaaggcaga tttaatttca atatatgaaa
     2401 tggaaagtaa ttcggaagtt tggtcggatt ggataaagca aaataatgaa tatgcaataa
     2461 atgaccgtaa ggcaatagaa gctggcggtg gagattatct gaattttatt gctataattc
     2521 tacaaaaaaa atgaattctt tagaaccaga cactataatt tgcgttctaa tatgtttacc
     2581 gatcggcatc aataatttta tctttgaggg taatgatttg aacatagaag aatacaagaa
     2641 gatacgaaat tgataaatta gaatttgaaa ggagttttga agaatgaaaa aatatgagta
     2701 tgtagaaatt aactataatg cgaaaggagt tgtattcctt tgtactgata aacataaaga
     2761 aattattgac agttacgcaa aaacggggta tcactacgca gggtttgtac ccacagaaat
     2821 tgacgcaaaa ggttgtatgc gaaagataga tttaattttt gaaaaagaag attaacttat
     2881 tttagggagt tggttctaat gataggactt aaaagacgag atatgaatta tattatgaaa
     2941 gttggtgcta aagctcaagg tgtttctgta tctgaattta gggctatgct acaatatacc
     3001 atagacaaaa ctatggaaag tacagaccca gatgtgcagg caaattttaa acgatacttt
     3061 ggaaataagc gcccaacacc agaggaatat attcatacga ttaccaaaaa gacaaaggtt
     3121 aaggtttaaa tgttgtaaag ggggcttgcc gtatgaaacg ctttatgtac aattcagtat
     3181 attcaagccc aatttaacag catactattt acaattaaat acgctatacc agtagctcgt
     3241 acaaaattta tattttgtgc gggctttttt aatacccgaa aagttttttt aattattttc
     3301 atttttttgg aagcaaatca caccttgctg tacagatatg gtgcggaaag agggataaac
     3361 acttttcaat tcatagctgg aaaggaggtg agattatgaa accgtctgac ttccaaaaaa
     3421 caattcagtg tcagtttgaa tgtaagctga aaaaaattgt caaaggtatt atctggaact
     3481 accgtaaaga attaaaacga agaaaaaaca aggaaatatc ttttagcgaa ttaccagaca
     3541 ttacggtaga aagtctggca acatgggacg actacgaaac aaactacaca atttttaatg
     3601 tgtgtggcat agatattaaa gtccttgatg atgaacttgc agaagctctc aaacagctac
     3661 ccgaaaaaaa acgtaacaat gtattgatgt attacttctt ggaaatgagt gatacagaga
     3721 ttgcagatat tatgaattat accagagggg ctgtgttcaa acacagacac cgtgccctag
     3781 aaactatgaa agagatacta aaggagaaga aatagaaatg aagaaaaagt acaagcaccc
     3841 gtcttattat ttgatttcat cagctatgga cggggatgaa actgcgattg agaaattact
     3901 ggcattctat gacccgtaca tatcaaagtg ttgtttacgt cctttatatg atgaatacgg
     3961 caacgtctat attgttgttg atatggaatt aaagggacgt attcgagaag ccttaatcaa
     4021 aatgatttta gactttgaga ttgatataga tatagaaacc gaagaagaat aagcagatac
     4081 cagcagggcg tgattggtta aatcccccct ctttcctgcc ctgctcctgc ttttatacat
     4141 ggaagcctac ggctttcgcc gattgttctt tgacaactta ataaagcaga cagatacgtt
     4201 tgtgatacag cgagccacgg ggactgtacg ccatgacctt tccgacaaga aagtgagcga
     4261 cccacgcagt gatccgagag caacttgtgg aatggtcgct ttgccatgac ctgctatcac
     4321 aggataatga tacgtccgca tggtgcggtt ctgcccacag gaatgggaat agttgagata
     4381 ctaacggagc tttccaaagc cgtctgtctg cttatgaaat gacgcacaga aaggagttgt
     4441 tgcaacatga ataatactga tgtgccgatt tgggaaaaat acacccttag tatagaagaa
     4501 gcatccagat attttcgtat cggggaaaag aagttgcgta ggcttgccga ggaaaatctg
     4561 gactctggct gggttatcgt caatggaaat cgtattcaga taaagcgaaa acagtttgaa
     4621 aaaattattg atacactgga cgaaatctga tgtcttagag ccgtagatat ggtataatat
     4681 tagtagcgta tcacggctca ttccttgacg gaaaggagct ttacactatg tcaaaaatga
     4741 aaagacaaga cagtaaagga cgcaatttgc gtcttggaga gagccagaga aaagacggaa
     4801 gatacgttta taaatatacc gatatattcg ggaagccaca gtttgtatat gcttggaaac
     4861 ttgtacccac agacaaaaca cctgttggaa aacgtgatga tatatcgttg agggaaaaag
     4921 aaaagcagat aaaaaaagac cttgacgacg gtatcgacac agtgggtggt aaaatgacag
     4981 tctgccagct ttacgaaaag aagaacaatc aaagaaagaa catcaagaga aacacaaaaa
     5041 taggacgaca gtatcttatg aacgcactgg aaaatgaccc attgggtatg agggcgattg
     5101 atacggtcaa gcagtccgac gctaaagaat gggctatcag aatgaatgac aaaggttatt
     5161 cctacaaaac gatagataac tataagcgtt ccttaaaggc ttcattctat atggcgatac
     5221 aagacgactg tatcagaaaa aatcctttca atttcaagtt gagtgatgtt ctggaagatg
     5281 atacggaagc aaaggttatc ctaacaccag agcaggaaga aaaactcctt gcctttatgg
     5341 aaacagataa tgtctacagc aagtatcgtg atgaagttat tcttctgctg gaaacgggac
     5401 ttcgtatctc tgaattatgc ggactgacaa cacacattga tatgcttaac cgtgtgatta
     5461 acatagacca ccagctattg cgtaatacag aggtgggtta ctatatttcc acacctaaga
     5521 caaaaaacgg gaagcgtgag cttccattga cagaaagagc atatcaggca cttgaacgaa
     5581 ttttaaagaa ccgaggaaaa gcacaaccgc ttgttgttga cggttacagc aacttcttgt
     5641 tcttgaaccg tgagggattg ccaaaggtgg caggaaatta tgaaagtatg gtgcgtgggc
     5701 tgattaagaa gtacaacaag acgtataagg acaagttgcc aaacatcacg ccccattcat
     5761 tcagacatac ttactgtaca aacatggcaa ataagggaat gaaccctaac accctgcaat
     5821 acatcatggg gcacgcaaac ataaccatga cattagggta ttatgctcac ggtactttcc
     5881 agtctgcaaa ggctgaatta gaaaggctgg cttcttaata tcgaaaatgt atcttactac
     5941 ttatttacta cttttggttg cattttcatg ctggtaaatg ccatcttatg cgaggtatct
     6001 tccaaaagga aaatgccaat aaagcccgaa aatatgggat atatcggcat ttaccaactt
     6061 atgaaaagat aatcagaaat ttagtaagtt tttgttataa taaatttaga cattatttaa
     6121 gcgagattaa ctgaatttaa tctcgcttaa atttatttct ataatattgg gggaatatta
     6181 tgaggaatac atttattatt gtggtcaatt attaaaattt tatacagttt attataaaaa
     6241 atttatactt ttctttatgt tgtttgccaa tattagtctc aaatacgagt accatactat
     6301 tctgacccac caacataaga aagagttttt taaatgaaaa agtcagataa aattaaattt
     6361 tatctgactt tttctatgtt tatcttatta gattatgtta atatctgttg accgaataag
     6421 cgcatactca gtcaactttc tatacctata ataatattgg gggaatatta tgaggaatac
     6481 atttattatt atggtcaatt attaatgttt tatacaactt acttaaaaaa atatatatta
     6541 catttcttcc tcatcaaatt cttcaatatt agtagcctgt ggtatacctt gtatagacat
     6601 attactagaa ccataaggag taggatatat attaggaggc atagtactag gcataactac
     6661 aggcatacct tgcattgtat tatgacatat aactcctggt atcatcataa gtacattagg
     6721 aggcatattt tgattacatg agaagttagg aatacccata gtattattca tattataccc
     6781 catattactg ttcatgttat taggcacatt gttaggcata cccatgttac tattcatatt
     6841 attaggcata ttgttaggca tacccatgtt actattcat
//
LOCUS       DACTZW010000138         6707 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.140, whole genome shotgun sequence.
ACCESSION   DACTZW010000138 DACTZW010000000
VERSION     DACTZW010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6707)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6707)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6707
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.140"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(<1..656)
                     /locus_tag="JAM15_18095"
     CDS             complement(<1..656)
                     /locus_tag="JAM15_18095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016440163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800158.1"
                     /translation="MKKDTSHIIKRAEHFQVILIGEGLMVGAVAGLIVLLYRILLGQA
                     GTWLSQILKFVEGSTIKIIAWFAVLAVLAWIVSKLVDWEPMISGSGIPQLEGEMTGKI
                     KQVWWRVLPTKFIGGFLSLMGGLALGREGPSIQLGAMAGKGISRALDRGKTEEKFLLT
                     CGASAGLSAAFHAPLAGVMFSLEEVHKNFSVSVLISVMTASLTADYISANFLGMESVF
                     "
     gene            complement(843..1352)
                     /locus_tag="JAM15_18100"
     CDS             complement(843..1352)
                     /locus_tag="JAM15_18100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HAT6800159.1"
                     /translation="MIGLKCGMVKLLEHQMIWDKSAKDVIILLKSIWDKTAIDIQHIG
                     STSIPSISAKPIIDIVVGVASLEEAKLYLERLEQCGIVFRGQDVPKQLLFAMGDFEKN
                     TRTHHIHVVEWNSVAWNNYINFRDYLNTFTDKAKLYDSHKQKLALQFEDNRKIYTQRK
                     QELINILLE"
     gene            complement(1427..1840)
                     /locus_tag="JAM15_18105"
     CDS             complement(1427..1840)
                     /locus_tag="JAM15_18105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HAT6800160.1"
                     /translation="MKMPKESIDTIMFAPCGMNCMVCYKHCYHKKPCAGCLNSDTGKP
                     EHCRKCKIKDCVCQKGLFYCFECFNFPCKLIKNLEKSYNKRYQASLMENSKFVQQYGL
                     EKFMQKQKERYTCSKCGGIISIHDRECSECQEKVK"
     gene            2277..2936
                     /locus_tag="JAM15_18110"
     CDS             2277..2936
                     /locus_tag="JAM15_18110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="HAT6800161.1"
                     /translation="MDEKILELLQEIQGNISNMQGSISGIEGTVNGMQGNINYMQGTI
                     GDMQGTISDMQGTISDMQGSINGIEGTISDMQGSINGIEGTISDMQSNINDIEGTISD
                     MQGSISSMDGTINSMQDSITDMQGEIKEVNSRLDNMEPDIKDLKTGQVETSSRLDTIQ
                     SDVTEIKSDVKINRNTLDTVIKHTSSLVEDTSDIKNDLNNIEIVTSKNWNDIAKLKSV
                     K"
     gene            complement(3543..3722)
                     /locus_tag="JAM15_18115"
     CDS             complement(3543..3722)
                     /locus_tag="JAM15_18115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAT6800162.1"
                     /translation="MLQTGKQGADKKYLDNMFFVKGYVEELLFLDNSYDIVFSCIVFH
                     HCTNVQNIFCIFWKW"
     gene            complement(3947..4480)
                     /locus_tag="JAM15_18120"
     CDS             complement(3947..4480)
                     /locus_tag="JAM15_18120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HAT6800163.1"
                     /translation="MQYISYYHSPIGNILLASDNVGLTGLWFENQKYYAYNLDQEHQE
                     KELPIFEQTKKWLDIYFSGEEPNFTPSLHMVGTPFQTTVWKILQQIPYGKTITYGEIA
                     HKVAQQKGISKMSAQAIGGAVGHNGISIIVPCHRVVGTNGSLTGYAGGIDRKIKLLSL
                     EKVSVQHYFIPKKGSAL"
     gene            complement(5298..5870)
                     /locus_tag="JAM15_18125"
     CDS             complement(5298..5870)
                     /locus_tag="JAM15_18125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HAT6800164.1"
                     /translation="MWIYQKTLEHPVNIRQADPRMAKYIMTQLGGPNGELAAATRYLQ
                     QRYTMPTGKSRALLTDIGTEEMAHVEIISSVLYQLIGSCTPEELKAAGLGSNYANFGH
                     GLQPVDSNGVNFTTSYINVFGDSVTDLHEDMAAEQKALATYYQLINLTDDPDLKDILR
                     FLGEREVVHYQRFGEALMDVYEFTECKHQF"
     gene            complement(5932..6195)
                     /locus_tag="JAM15_18130"
     CDS             complement(5932..6195)
                     /locus_tag="JAM15_18130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HAT6800165.1"
                     /translation="MSLNRRELLERISEYQFACIELNLYLDNNPRDKKALDLYNRYCD
                     KFTQAVCDYESKYGALTNFGYESSEYPWSWISEPWPWDKSFYK"
     gene            complement(6195..6416)
                     /locus_tag="JAM15_18135"
     CDS             complement(6195..6416)
                     /locus_tag="JAM15_18135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HAT6800166.1"
                     /translation="MGYLKEDKQDYCCEFARPYINRQIYDDTYNPKTALKRGTLFPEL
                     DLIESNNYNDWLYSNPKNRVRAKKGGNMY"
BASE COUNT         2356 a         1140 c          816 g         2395 t
ORIGIN      
        1 tggaatacag actccattcc taggaaattg gctgaaatat agtctgctgt caaagatgct
       61 gtcatcacag aaattaaaac agatactgaa aagtttttat ggacttcttc aagtgaaaac
      121 ataacacctg ccagtggtgc atgaaaggct gctgataatc cagcacttgc cccacaggtt
      181 aacaggaatt tttcctctgt cttccctcgg tcaagagctc tagaaatacc tttacctgcc
      241 atagcaccaa gctgaatgga aggaccttcc cttcccaaag caagaccacc cataagtgat
      301 aagaatcctc caataaattt tgtgggcaac actcgccacc atacttgttt tattttccct
      361 gtcatttccc cctcaagctg agggatacca cttccagaaa tcattggctc ccagtccacc
      421 aactttgata caatccacgc aagtactgca agtactgcaa accaagctat tatttttatt
      481 gtagaacctt ctacaaattt taaaatttgg ctaagccaag taccagcctg ccctaaaagt
      541 atcctgtata aaagcacaat caaaccagcc acagccccaa ccataagtcc ttcaccaatc
      601 aaaattacct gaaagtgctc tgcccgtttg ataatatgag atgtatcctt tttcatactg
      661 ttcctccttc atccaataat tctacacaat ctgaacctcc aatgactaaa gtcatgagtg
      721 tgtacagata ttttttaatc aacaaaaata gatttttatt tactaaatat aagaaaataa
      781 ttgttcaatt tctcaataaa tgtaaattta ttcttttagg tatttattct ccacagtcgt
      841 gcttattcca gcaaaatatt tattagttct tgctttctct gtgtatagat tttacgattg
      901 tcctcaaact gtaatgctaa tttttgttta tgactatcat agagttttgc tttgtctgta
      961 aaagtattta gataatctcg aaaattgata taattattcc atgcgacact attccattca
     1021 acaacatgaa tatggtgagt acgagtattt ttctcaaaat ctcccatagc aaaaagtaat
     1081 tgttttggta catcctgacc tcgaaaaacg attccacatt gctctaacct ttcgaggtat
     1141 aatttagctt cctctaaaga agcaacacct acaacaatat caataatagg ctttgcgcta
     1201 atactgggaa tagaagtgct tccaatgtgt tgaatatcaa tggcagtctt atcccatata
     1261 cttttcaata atataatgac atcttttgca cttttatccc atatcatctg atgttccaat
     1321 aatttaacca taccacattt taaacctatc actatatacc acctcaatat aatccacctt
     1381 tatatatata ttacaatttt ttctatcttg ataaacagtg atttagctat ttcacttttt
     1441 cttgacactc gctacattcc ctatcatgaa tagatataat tcctccacat ttagaacaag
     1501 tatatctctc cttctgcttt tgcataaact tctctaaacc gtactgctga acaaatttac
     1561 tattttccat aaggcttgct tgatatctct tgttataact tttttcaaga ttttttatga
     1621 gtttacaagg aaaattgaaa cattcaaaac aataaaacaa ccctttttga cagacacaat
     1681 cctttatttt acacttacgg cagtgttctg gctttcctgt atcgctgttc aaacaaccag
     1741 cacatggctt tttgtgataa caatgcttat agcaaaccat acaattcatt ccacaaggag
     1801 caaacataat cgtatcaata ctctcttttg gcattttcat aacattttac tcctttcaaa
     1861 aatccaattt gtcgaattgt tatatattca tattgtaaca taaaaaatag ctaaaaaatt
     1921 catgcacttt cattgccaat aaattttcaa ggaaatatga aagtttaaaa ctaagaataa
     1981 aaagaaataa aaaggaagct actaatcaaa atattcaaac acaagtaatc aattatgata
     2041 ttaccagcag ttttaaatac aaatataacc acatatgcct caaaaacact tattatagta
     2101 tcttagacac ttagacaata cacaagattc attaataaaa aagttctcaa tatagatata
     2161 tttaaccatg ttttgaatag cagataatta tatgattaaa aattaaatat gacatagcgt
     2221 ttgtggaata taacacctaa attatgttat aataataaaa caggagtgtg atagttatgg
     2281 atgaaaaaat attagaatta ttacaggaaa tacaaggtaa tattagtaat atgcaaggta
     2341 gtatcagtgg tatcgaaggt actgttaatg gcatgcaggg taatattaac tatatgcaag
     2401 gtactattgg cgatatgcaa ggtactatta gcgatatgca aggtactatt agcgatatgc
     2461 aaggcagtat caatggtatc gaaggcacta ttagcgatat gcaaggcagt atcaatggta
     2521 tcgaaggcac tattagcgat atgcaaagca atatcaatga tatcgaaggt actattagcg
     2581 atatgcaagg cagtatcagt agtatggatg gcactattaa tagtatgcaa gacagtatta
     2641 ctgatatgca aggtgaaatt aaagaagtca atagtagatt agacaatatg gaacctgata
     2701 ttaaagactt aaaaactgga caagttgaaa ctagtagtag acttgataca attcagagtg
     2761 atgttacaga aattaagtca gatgtaaaaa ttaacagaaa tacattagat acagtgatta
     2821 aacatacctc ttcattagta gaagatacat cagatattaa aaatgattta aacaatatag
     2881 agatagtcac atctaagaat tggaatgata ttgctaaatt aaaatcagtt aaataatata
     2941 ccatagtaaa aaatacctga aaatttcaca tacttcttta aagttatacc aaattttata
     3001 cagaaatact gattatccga caacacactt tacttataaa taatttatta aaaaatactc
     3061 attttatcct aaaattaaca cgactaaatg agtcttgata taataataaa aaataaggga
     3121 gattgaacac taaaaagttg tgtatctccc ttatattcta taatatagtt atataatttt
     3181 tcagcctaaa ataaaagtcc atctttgatt aaaacatatc cccttatcac ttataaaagg
     3241 ataaaatctt gttttcattt ttccatttat atcttcttgc ttaagagtaa taattttttc
     3301 ttttgatact ttaagtgttt ggttaaattt aaccaatcga ctaagtttta ttcaacatct
     3361 atttttcata ttttccaata cttaatctat tttttataaa taattctttt atttctaact
     3421 cacttacatt ttttacataa aacgaagcat ataaatttca accttatctt gtatggttct
     3481 taatacttaa tgagtagctt aagtatcaat cattataaat tttctcctta tatttaacac
     3541 tcttaccatt tccaaaatat acaaaatata ttttgaacat ttgtacaatg atgaaataca
     3601 atacatgaaa atacaatatc ataactgtta tctaaaaata gaagttcttc aacataacct
     3661 ttcacaaaga acatattatc taagtatttt ttgtctgctc cttgttttcc tgtttgtagc
     3721 atataaatta ctgcatctaa acatataact actcacacga aaaaagaaaa taaacttcca
     3781 aaatacaagc tctaaaacta cctctaaagt tatataatgt ttactaggaa taaggttgta
     3841 taacatatag tttaaagaat agttttttaa aattgcaagt tattgctttc aaaattagat
     3901 gtttatatat caaataaatg attaagaatt tctaaattta atggctttat aatgcactcc
     3961 ctttctttgg gataaaataa tgttgcacag atactttttc taaagataac aattttattt
     4021 ttctatcaat tccaccagca taccctgtca aactcccatt tgttcctaca acacgatgac
     4081 atggaacaat aatagagatt ccattatgcc ctactgcacc accgattgct tgtgctgaca
     4141 ttttagatat tcctttttgt tgagcaactt tatgtgcaat ttctccataa gtgattgttt
     4201 taccatatgg tatttgttgt aaaattttcc acactgtagt ctggaaagga gtacctacca
     4261 tatggagtga tggtgtaaaa ttgggctctt ctcccgaaaa ataaatatct agccatttct
     4321 ttgtctgctc gaaaattggc aattcttttt cttgatgttc ttggtcaaga ttataagcat
     4381 aatacttttg attctcaaac caaagaccag ttaacccaac attatctgat gctaaaagaa
     4441 tatttccaat tggactatgg taatagctaa tatattgcat acaattcctc cttatattct
     4501 gaaaacttca ctcaaatcat tagacacttc ttttctatct gccattatgt aaaaacatac
     4561 taatataatt tccttctgac tacactttcg ttataatatc tatcctcata tcatattagt
     4621 tttatattta cctgaatctg ttcatccttt ttttcctttc cctttgatgg atataaaatt
     4681 catacattta agcttcctac tgtattaact tttatagaag tgtatattat aattttatca
     4741 ctaaatagac aaaaaaatat cgatataaca tcaagaaata ttttactgag tttcacttat
     4801 taaaagcaac tgaatttcta aagggtacag atgagctaat aagtgatatt gatataaaag
     4861 ttgtttttca ttaagtaatc tattttagta aatgttttaa agaaaaaacg ggatattctc
     4921 caaaagtgta cagaaatata aaaaaagaga tatgattttt tatttctttt gattatccaa
     4981 agagtaaata aaaaatattg taaaaaactt actaacaacg gcaatgcttt gaactatggt
     5041 aatactttga acttttgatt ggactttttt tgctaaaata atatatttaa atagcaaagt
     5101 aatctgttta atcaataaaa aataagagat aaaagaaatc aactaaaacc tttacctctt
     5161 attttgatag tttatcagag ctaatattta cactcttttt atttttgata cttcattaaa
     5221 aatgatgctt attctctttt catttttaat acttcattaa aattgatgct tactctctgt
     5281 tcacttttaa tacttaatta gaactgatgc ttacactctg taaactcata aacatccatt
     5341 aatgcttcac caaatctttg atagtgaact acttccctct cacccaaaaa tctcaatata
     5401 tctttcaaat cagggtcatc agttaaattt attaattgat agtacgtagc caatgctttt
     5461 tgttcagcag ccatatcctc atgtaaatca gttaccgaat cgccaaagac attaatataa
     5521 cttgtagtaa agtttactcc attagaatct actggttgaa gaccatgtcc aaaattagca
     5581 taattactac caagtccagc agccttaagc tcttccggag tacaactgcc tattaattga
     5641 tataacactg aagaaattat ctcaacatgg gccatttcct ctgtacctat atcagttaaa
     5701 agtgcgcgag attttccagt tggcatagta tatctttgtt gaagatatct agttgcagct
     5761 gccaactcac cattaggtcc tcccaactga gtcatgatat attttgccat tctagggtct
     5821 gcttgtctta tgttaactgg atgttccagt gttttttgat aaatccacat attatcttac
     5881 tcctccttaa tatatattta ataataattc taattttaaa acttaataat tttatttata
     5941 aaatgatttg tcccatggcc aaggttcaga tatccatgac caaggatatt cacttgattc
     6001 atatccaaaa ttagttaatg ctccatattt agattcataa tcacacacag cttgtgtaaa
     6061 tttatcgcag tatctattgt ataaatcaag agctttctta tcccttggat tgttatctaa
     6121 atataaattt aattctatac aggcaaattg atattctgaa attctctcta aaagttctct
     6181 tctatttaat gacattagta catgttaccc ccttttttag ctctaactct atttttagga
     6241 tttgaatata gccaatcatt atagttattt gactctatta aatctaattc aggaaataaa
     6301 gtacctcttt ttaatgctgt ttttggattg tatgtgtcat cataaatttg acgattgatg
     6361 tatggtctag caaattcaca acaatagtct tgtttatcct cttttaaata tcccattaat
     6421 tatcctcctt aatttttaga attttaaaat agcattattt ttaaaaatta tatacttgtt
     6481 ctatattata gtcagtagtt ttaataggtc tttaataaga ttaaataatt aaataagtat
     6541 ctttttttgt tcttatttta cctataaaaa ttttcctaat taatctttca taaatatcta
     6601 ttttaaataa ataatataga gtttatacaa ttttttataa cttaattact atttactata
     6661 tattattcat ttttaaataa aatgtgatta ttttttatta aaaacga
//
LOCUS       DACTZW010000139         6534 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.141, whole genome shotgun sequence.
ACCESSION   DACTZW010000139 DACTZW010000000
VERSION     DACTZW010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6534
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.141"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            <1..303
                     /locus_tag="JAM15_18140"
     CDS             <1..303
                     /locus_tag="JAM15_18140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAT6800167.1"
                     /translation="NDDFSSNQSVRVLDQIANDIAILFNDKYLGKVPNDKAGRISFWN
                     DVVKHHKELENIRAIEDFKTDDVSVELGSDKKTVIVSDAVKIINAMSKLYMTVSVS"
     gene            342..800
                     /locus_tag="JAM15_18145"
     CDS             342..800
                     /locus_tag="JAM15_18145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014315266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HAT6800168.1"
                     /translation="MNVKDTISASLAECFVTIEGKRYNFMQAINLEAKMEKTKSEVPI
                     LGKTTKGNKTTGSKITGSATFHFNTSIFRELLYRYKETGEDIYFDIQVTNEDPTSSVG
                     RQTVILKDCNMDSGIITKFDADGEYLEEDMDFTCEDWELVEKFNIISGME"
     gene            870..1310
                     /locus_tag="JAM15_18150"
     CDS             870..1310
                     /locus_tag="JAM15_18150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAT6800169.1"
                     /translation="MSNLSAFLAQNAIKVDNVKYIASNRFLDEDNKPVEWELRVLSSE
                     EDEALRRKCTNRVKVIGNNGKHTGQYTSEIDYNSYVAELCVASTVFPDLKDAELQNSY
                     GVMGEAQLLKTMLTAGEYVNYTVKVNEVNGFDTSFEDKVEEAKN"
     gene            1574..2137
                     /locus_tag="JAM15_18155"
     CDS             1574..2137
                     /locus_tag="JAM15_18155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HAT6800170.1"
                     /translation="MFCSSCGAEITGVGKFCSSCGAPVEIEIVDNKDIETKQDLIVNV
                     NNTEINMTEIYRKYRKEKVNAIKNVMEISGLNIKEAKKIVDSSFEELKISFIDDTMSN
                     SEKEKIINNQNRKNNIEKAQQESVACCPKCGSTSLSAQKKGFGIGKAVVGASLTGGIG
                     LVAGNLGAKKVRVTCLNCGKQFWAGKK"
     gene            2215..4581
                     /locus_tag="JAM15_18160"
     CDS             2215..4581
                     /locus_tag="JAM15_18160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HAT6800171.1"
                     /translation="MATIQTSIRIFDGMTPAFRHMTTAMNIVLSSFEQLQRTSSNAVN
                     ANSIIRAREELARAEAGFDRLERQIREADEQQKRFNDDVKKGASSTDKLVENAKRLVA
                     TYIGLRSVGGLINLSDQMTNTNARLSMINDGQQSDSGLNKMIFQSAERARASYLDTAK
                     IVSRVGMNAGKAFSSTKEIVAFAEQLNKKFVIAGATTEETNSALLQLTQGLGSGVLRG
                     EELNAVFESAPNIIQSIADYLDVDIGKIRGMASEGMLTADIVKNSLLTAAEQTNAEFE
                     KMPYTFSQIWTSIKNNCIMIFGVIQKKIEQAMSSRGFRTFIDNFIDSLYVLGNVAYNI
                     FNGIINILGSPFFQAFTNTIIVCVSLIAQALGWVITQALNIANVFAQNWSIIAPIVLG
                     VAAAMLVYNNALLLSIANKVKDIALSAKTLAMNFAHIIAESYRAAALVATTIAQDGLN
                     AAMAACPITRILYGIIAIVVAFFVAIAVINKFAGTSYSAIGIIAGALAGLTAFIINSV
                     FFWVNVFISFAEFFTNVLDNPVYSVKKLFFNLATAVLNNLISMTQGCDEFATNLANSI
                     IDGINGALKAWNKFVDVLNKFGGLGDKLGLGKADMVGHTKSITSTLQKAKGDLNKWLG
                     AEPEGYKSFKQLEYKNVGDWAKNGYAFGQNLENKIKDTFDISKIAEKAKKDLGLDDLW
                     DDKYGLGDGIGSAGLNSPLGDAAKGAKDTAGNTAKMAKTMDKSQEDLKYLRDIAEQEV
                     INRYTGVNIKIDMNNTNNISKDTDLDGIVNVLTEKLNDAMVVSAEGIV"
     gene            4597..5286
                     /locus_tag="JAM15_18165"
     CDS             4597..5286
                     /locus_tag="JAM15_18165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAT6800172.1"
                     /translation="MAYDFYLDGVQLPITPGKLEVKIINKNKTVDLINDGEVNILKTP
                     GLSEISFEAEFTHNKLPFYRGQFKDVQFFLSKLELLKTDCKPFQFIVSRQLGNKVLFN
                     TNMKVSLEEYTILEDADNGSDTKVSIKLKQYRDYSTKKLVPATPKSDSGRPNVKIEPK
                     RVDSVNAPNTKTYTVKSGDSLWSICQKQLGNGSLYKKVYELNKSMMDKANKGKKVPKY
                     TVYKGQVLRLG"
     gene            5279..>6534
                     /locus_tag="JAM15_18170"
     CDS             5279..>6534
                     /locus_tag="JAM15_18170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase"
                     /protein_id="HAT6800173.1"
                     /translation="MADELVLANDRDIRLVIAHLEDFYEPVVLDGITWEIERRGIPSK
                     LEFTIVMDKILEFCEGNSVRLYYKGVGIFYGYIFQKKRDKENHIKIVAYDQLRYFKNK
                     DTYVYSNKTASELVKMLSKDFNLKYNVIEDTKYKISRVEENKTLFDMILTALDDTLRE
                     KKEMYVLYDDFGRITLKNVASMKLDTVMNNDVIEDFDYNSSIDSDTYTKIKLVRDNEE
                     SGKRDVYIAQDSTHMRSWGILQMFDTVDKNMSEAEIKQKCDILLKLYNKKTKSLSLKN
                     ALGDIRVRAGCLIPVFLDLGDIELQNYMLVEKVKHTFENNSHFMDLTLVDGDEFASYS
                     SSSYSSGNTNNKDEKKNGPAQSTTKKNTGKKVPAIFTAYYPGNNAMEGGKTDCNGKPL
                     DVKSRTVAGPMNREGVKKTWYTDDFL"
BASE COUNT         2566 a          748 c         1324 g         1896 t
ORIGIN      
        1 aatgacgatt tctcaagtaa tcaaagtgtt agagtattag accaaattgc taatgatata
       61 gcgattttat ttaatgataa atatcttggt aaagtaccta acgataaggc aggaagaata
      121 agtttctgga atgatgttgt taagcatcac aaagaattag aaaacattag agcaatagaa
      181 gattttaaaa ctgatgatgt tagtgtggaa cttggaagcg ataagaaaac tgttatagtg
      241 agtgatgcag ttaagattat taacgctatg agcaagcttt atatgactgt ttctgttagt
      301 taagagagga gtgtgataaa tagatgccta aaaacgcacc tatgaatgtt aaagatacaa
      361 taagtgcatc tttagcagaa tgttttgtaa caatagaggg taaaagatac aattttatgc
      421 aagctattaa tttagaagct aagatggaaa aaacaaaaag tgaagtacca attctaggaa
      481 aaactacaaa gggtaataaa acaacaggta gtaaaattac aggtagcgca acatttcatt
      541 tcaatacttc tatatttaga gagcttctct ataggtataa agaaactgga gaagacattt
      601 actttgatat acaagttact aatgaagacc caacaagttc agtagggaga cagacagtaa
      661 ttttaaaaga ctgtaatatg gacagtggaa taattactaa atttgatgca gatggcgaat
      721 atctagaaga agatatggac tttacatgcg aggattggga attagttgaa aagttcaata
      781 taataagtgg aatggagtaa aatacacatt tataaattat agatgtgtat tttttatgtt
      841 aaaaattaaa ataaaaggag aataagaata tgagtaattt aagtgctttt ttagctcaaa
      901 atgcaataaa ggttgataat gtaaaatata tagctagtaa taggttttta gatgaggata
      961 ataaaccagt tgaatgggaa ttaagagttt tatcttcgga ggaagatgaa gcattaagaa
     1021 gaaagtgtac taatagagtt aaggttatag gtaataatgg taagcacaca gggcaataca
     1081 ctagtgaaat tgactacaac agttatgtag ctgaattatg tgtagcatca acagtatttc
     1141 ctgacttaaa ggatgccgaa ctccaaaata gttatggagt aatgggagaa gctcagttat
     1201 taaagacaat gcttacagca ggtgagtatg tcaattatac agtaaaagtg aatgaagtca
     1261 atggatttga tacatctttt gaggataaag tagaagaagc aaaaaactaa tcagaggtgg
     1321 cgattttgat gctagcatca ctcattattg tattcaaaaa ttaaagtgga agccaagtga
     1381 atatatgaat ttagaagtta atgagagagc gttagcagcc gcctcaatac ttataaagat
     1441 agaggatgaa gaggaagcaa tgaaagaagc tgaaagagag aaaaagagag ggcgaagaag
     1501 ataatgtata atgtaaaaat tttacttata tagtataata atattataaa attattatgc
     1561 tagggggatt attatgtttt gttcaagttg tggagcagaa attacagggg taggtaaatt
     1621 ttgttcgagt tgtggagctc ctgtagaaat tgaaatcgta gataataaag atattgaaac
     1681 aaaacaagat ttaattgtta atgtaaataa tacagaaata aatatgaccg aaatttatag
     1741 aaagtataga aaagaaaaag taaatgcaat aaaaaatgta atggaaataa gtggtttgaa
     1801 cataaaggaa gcaaaaaaaa tagtggattc ttcttttgaa gagttaaaaa ttagttttat
     1861 tgatgatact atgagtaatt cagaaaagga aaaaataata aacaatcaaa atagaaaaaa
     1921 taatattgaa aaagctcaac aagaatcagt tgcttgttgc cctaagtgcg gttcaacatc
     1981 tttgtcagct caaaaaaaag gttttggtat aggaaaagca gtggtaggag cgagtttaac
     2041 tggtggaata ggtttagtag ccggaaattt gggagcaaag aaagttagag ttacatgctt
     2101 aaattgtgga aaacagtttt gggcaggcaa aaaataaatg tattcataat aaaaacactt
     2161 actaatttag taagtgtttt tattatataa attaacagaa aggagagtga aaaaatggct
     2221 acgatacaaa catctataag aattttcgat ggaatgacgc ctgcatttcg gcatatgaca
     2281 actgctatga atatagtact gagttcattt gagcaattac aaagaacttc tagtaatgca
     2341 gtaaatgcta atagcataat aagagctaga gaagaattgg caagagcaga agctggattc
     2401 gatagattag aacgacagat aagagaagct gatgaacaac aaaaaagatt taatgatgat
     2461 gttaaaaaag gagcaagtag tacagacaag ttagtagaaa atgcgaaaag attagtagca
     2521 acttatatcg gattgagaag cgttggtggt ttgattaatt taagtgacca aatgactaac
     2581 actaatgcaa ggcttagcat gataaatgat gggcaacaat cagatagtgg acttaataaa
     2641 atgatatttc aatcagcaga aagagcaagg gcatcttatt tggatactgc aaaaattgta
     2701 agcagggtgg gtatgaatgc aggtaaggca tttagtagta caaaagaaat agtagcattt
     2761 gctgaacaat taaataaaaa attcgtaatt gcaggagcaa cgacagaaga aaccaattca
     2821 gcacttttac agttgactca aggtttgggt tctggtgtgt tgagaggaga agaactgaat
     2881 gctgtatttg agtcagcacc taatattatc caatccatcg cggattacct cgacgtggac
     2941 ataggaaaaa taagaggaat ggcatcagag ggaatgttaa cagcagacat tgtgaaaaat
     3001 tcattactta cagcagcaga gcagactaat gcagaatttg agaagatgcc ttatacattt
     3061 tctcaaattt ggacttcgat taaaaataat tgcatcatga tttttggtgt tatacaaaaa
     3121 aagatagaac aagctatgtc tagccggggt ttccgaacct ttatagataa ttttatagac
     3181 tctttatatg tgcttggaaa tgtcgcttat aacattttta atggaattat aaatatatta
     3241 ggaagtccat tttttcaagc ttttacaaat actattattg tatgtgttag cttaatagca
     3301 caagcattag gctgggtaat aacacaagca ttaaatattg ctaatgtatt tgctcagaac
     3361 tggagtatta ttgcaccaat agtacttgga gttgcagctg ctatgttagt atataacaat
     3421 gcactattac ttagtatagc taataaagta aaagatattg cgttatctgc taaaacttta
     3481 gcgatgaatt ttgctcatat aatagcagag tcttatagag cagcagcatt agtagcaacc
     3541 acaattgcac aggatggatt gaacgcagca atggcagctt gccctatcac tcggatttta
     3601 tatggaatta tagccatagt tgttgccttt tttgtagcta tagctgtaat aaataaattc
     3661 gcaggaacat cttattcagc aattggaatt attgcaggag cattagcagg tttgacggcg
     3721 tttattataa atagtgtgtt tttttgggtt aatgttttta tatcgtttgc tgagtttttt
     3781 acaaatgtat tggacaatcc agtttattca gtgaagaaat tattttttaa tttagctaca
     3841 gcagtattaa ataatcttat atctatgaca caaggatgtg atgaatttgc tactaattta
     3901 gcaaactcta tcatagatgg aatcaacgga gcattgaaag cctggaataa attcgtggat
     3961 gttttaaata aatttggggg acttggagat aagctaggac tcggaaaagc tgatatggtt
     4021 ggtcatacaa agtctattac aagtacacta caaaaagcta aaggtgattt aaataagtgg
     4081 cttggagcag agccagaggg atacaaatcc tttaaacaat tagagtacaa aaatgtcgga
     4141 gattgggcta aaaatggata tgcctttggt caaaacttag aaaataaaat aaaggatact
     4201 tttgacatta gcaagatagc cgaaaaagca aaaaaagatt taggcctaga tgacctttgg
     4261 gatgacaaat atggactagg agacggaatt ggttcagcag ggcttaattc tccacttggg
     4321 gatgctgcca aaggagcgaa agatactgcg ggaaatactg caaagatggc aaaaacaatg
     4381 gataaaagtc aagaagacct taaatatctt agagatattg cagaacagga agtgatcaat
     4441 aggtacacag gagtaaacat taaaattgac atgaacaaca caaataacat aagtaaagat
     4501 actgacttag atggaatagt aaatgtacta actgaaaaat taaatgacgc tatggttgta
     4561 tctgctgagg gaatagttta ggaaggaggt gtttaaatgg cttatgattt ttatttggat
     4621 ggagtacaat taccaattac acctggaaaa ttagaagtaa agataataaa caaaaataag
     4681 acagttgatt taataaatga tggagaagta aacatattaa agactcctgg tctatctgaa
     4741 ataagttttg aagcagaatt tacacataat aaattacctt tttatcgtgg tcaatttaaa
     4801 gatgttcaat tctttttaag taaactagaa ctattaaaaa cagattgtaa gccattccaa
     4861 tttattgtgt ctcgacagct tgggaataaa gtactattta acactaatat gaaagtatcc
     4921 cttgaagaat atacaatctt agaagacgcc gacaatggct cagatacgaa agtttctatt
     4981 aaattaaaac aatatagaga ttattcaact aaaaagttag ttcctgcgac acctaaaagt
     5041 gatagtggga gaccaaacgt aaaaatagaa cctaagaggg tcgattcagt caatgcacca
     5101 aacactaaaa catatacagt taaaagtggt gattctcttt ggtcaatttg tcaaaaacaa
     5161 cttggaaatg gttctttata taaaaaagta tatgagttaa ataaatctat gatggataaa
     5221 gctaacaagg gtaaaaaagt gcctaaatat actgtttaca aggggcaggt gttgaggctt
     5281 ggctgatgaa ttagtattag caaatgatag agatataagg ttagttattg cccacttaga
     5341 agatttctat gaaccagttg ttttggatgg aatcacatgg gaaatagaaa ggcgaggaat
     5401 accaagtaaa ttagaattta caatagttat ggataagata ttagagtttt gtgagggaaa
     5461 ttctgtaaga ttatattaca agggtgtagg catattttat ggatatatat ttcagaagaa
     5521 aagagacaaa gaaaatcata tcaagatagt tgcctatgac cagttaagat attttaaaaa
     5581 taaagatact tatgtatata gtaataaaac tgcaagtgaa cttgtaaaaa tgttgtcaaa
     5641 agattttaat ttaaaataca atgttataga agatactaag tataaaatat caagagttga
     5701 agaaaataaa acactctttg atatgatatt aactgcacta gatgatactc taagagagaa
     5761 aaaggaaatg tatgtactct atgatgattt tggaagaata acattaaaga atgttgcatc
     5821 aatgaaatta gatactgtta tgaataatga tgtaatagaa gattttgact ataactcaag
     5881 cattgatagt gatacttata caaaaattaa acttgtcaga gacaacgagg agtcaggtaa
     5941 aagagatgtg tatattgctc aagattctac acatatgaga agttggggaa tacttcaaat
     6001 gtttgataca gtagacaaaa acatgagtga agcagagata aagcaaaagt gtgatatact
     6061 tctaaaatta tataataaga aaactaagtc attaagttta aaaaatgcac ttggtgatat
     6121 tagagtaaga gcaggttgtt taatacctgt ttttttagat ttaggagata tagagttaca
     6181 aaattatatg ttagttgaga aagtaaaaca tacatttgaa aataattcac atttcatgga
     6241 tttgaccttg gttgatggag acgaatttgc ttcttattct tcatcttcat atagtagtgg
     6301 aaatactaac aataaggatg aaaagaaaaa tggtcctgca caaagtacta cgaaaaaaaa
     6361 tacaggtaaa aaagttcctg ctatatttac tgcatattat ccaggaaaca atgcaatgga
     6421 aggtggaaaa acagattgca atggaaagcc acttgatgta aaatcaagaa ctgttgctgg
     6481 tccaatgaat cgagaaggag ttaagaaaac ttggtatact gatgattttc taaa
//
LOCUS       DACTZW010000140         6317 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.142, whole genome shotgun sequence.
ACCESSION   DACTZW010000140 DACTZW010000000
VERSION     DACTZW010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6317
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.142"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(128..526)
                     /locus_tag="JAM15_18175"
                     /pseudo
     CDS             complement(128..526)
                     /locus_tag="JAM15_18175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427430.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1000..1884)
                     /locus_tag="JAM15_18180"
     CDS             complement(1000..1884)
                     /locus_tag="JAM15_18180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAT6800174.1"
                     /translation="MDTKKENNYENYICVGSSNVSNAMKMYLKEIEEYKMLSAGEEVE
                     LAKEIINSSSVAKEKFINSNYRLVVSIAKRYKRDSIDMLDLIQAGNIGLIKAVEKYDY
                     KKGYKFSTYATWWIKQSITRYIDDCENTIRIPIHLHQRINFVKKKKQELLNVLLREPT
                     IDEIADACGLEVDKVLELLRRDKNVVSLDTPLKEDEDSSLVEFIPSDADFKDVVIHEV
                     EQHNLKEKIEELLTGLGEQEQQVLRMRFGIDDDDPKTLEQIGKVFGVTRERIRQIEAK
                     AIRKLRHPSKLKQLKHFY"
     gene            complement(2175..2651)
                     /locus_tag="JAM15_18185"
     CDS             complement(2175..2651)
                     /locus_tag="JAM15_18185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800175.1"
                     /translation="MSKELVKDRVIKYLIEDLLVPQDMIDTNVELAEFEEGAEGILDI
                     VVNVKDEEDYYAPVMIVQCLDEDVELEGEVLQKQIEFLEEVDNITMSGRLVLTNGDAM
                     MYADWRGEEYDTEAALPTYDIMVKEFHEMEQQVKDLEEHHHHDENCGCGCNHHHEN"
     gene            2918..4093
                     /locus_tag="JAM15_18190"
     CDS             2918..4093
                     /locus_tag="JAM15_18190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HAT6800176.1"
                     /translation="MKFKKQISSIVVSTMLVLGSINLSYADGTNVVTLGANLSESQKQ
                     QMLNYFGVKKDQVLVLDVTNAEERQYLQGVATEGQLGKVTISCSYVEPTKKGNGINVK
                     TANLTWVTSSMIASTLTTAGLEDANVIAAAPYPVSGTGALTGIMKAFEDASGKKLDET
                     KKEIASEELVVTGDLGDDIGQEKATGVMNDIKTEIVKNGTKDTNQIANTINNVVNNYN
                     ITITPEQKEQIKGVMKKIADQNYDYNSMKNTLDNVSDNVNEQLKKLGESVKGSGILDT
                     IGGWFSGIGDWFSGLFSGGDKKDLGILNNTNDESLGSDAVINSTEGVQINPQNNTNSN
                     NDNDTNSSKNDTSSNNENNDSSQTNENNTTNNSENQSNNNDSVGFFEKIKNWLSGLF"
     gene            complement(4174..4977)
                     /gene="proC"
                     /locus_tag="JAM15_18195"
     CDS             complement(4174..4977)
                     /gene="proC"
                     /locus_tag="JAM15_18195"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HAT6800177.1"
                     /translation="MKKIGFIGAGNMASAMIGGIVNSKLVEPNMVIASAYSQETLDRI
                     YANFGINTTKDSKEVTRTSDIVIVAVKPDIYDDILEEIKDFIDDNKIIVTIAAGKSIK
                     DIESIIGEDKKIVRTMPNTPALVNEAMSSLSINKNINNEDLEVVTEVFNSFGNTEVVP
                     EYLIEAVIGASGSAPAYVFLFIEAIADAAVIAGMPRPQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPGGTTIEAVKVLEEEGFRASVIKAICACIEKSKKMSE"
     gene            complement(5017..5601)
                     /locus_tag="JAM15_18200"
     CDS             complement(5017..5601)
                     /locus_tag="JAM15_18200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAT6800178.1"
                     /translation="MNKDIGAKIKQLRTQKQMTLKDMSEKTNLSIGFLSQLERGLTSV
                     ATDSLGKIASVLDVELTYFFMKPKEHKRAVLRSYEKEVFDVENSTFIHYHLSSSLKEK
                     TMLPRLIEILPSKSSEEICCYVHEGEEFVYVLEGTLTVFLGDEQIEMYPGDTIHYNSE
                     KNNHNWVNYTNKVVKILVVSIPNPFEKSDAVKEA"
BASE COUNT         2129 a         1054 c          681 g         2453 t
ORIGIN      
        1 gggtttccag caattcaagt agtattggat aggttctatc ctatctctac atataggttt
       61 ccctatatgc tgactatttt agctactaac tcatgactaa agtcacgagt gtgcgtagct
      121 attttttaat caatatttta gtaaatttta cggtaagtaa aaacctctct ccttcaaatc
      181 ctatagcaaa tatacttaca agttgctttg agaaaataac tcctaatata gctacaacta
      241 tgcatatacc aactattata tttaaaacat tgtttaaaaa ctttagtgct tgcttttcac
      301 cttgtttact acttatatct tgatacattg gaataaaagt agtaactata gcagtaccta
      361 ttgctgcaaa tataatattt ggtatattca tagctgttaa ataactctct gtatataagc
      421 ctgtaccata aattgatgat aatactaatt ctctacccat tccaagaatc ttagagatta
      481 tagtaactat catcaaataa aaagttgctt tagctacctt gctcatttta tcactccact
      541 tctaacatac ctctttttaa tcaagtaaaa tttagctcat tagatataat tctatcaact
      601 aatttgcctt gcttagccct atcaaaatat aattaacacc tatttcttaa tatatcacaa
      661 actacattat tcttcatatt tttttatttc tccaataagt tttacatttt tcctatataa
      721 attgtatagc ttcaattata ttcaaagaaa tggagttgct acccgataac tttaaaagta
      781 aaaaacagat tttattatct ttttaaacta tattctaaca tattttgtcc atattgagaa
      841 attttactaa actattatgt actttattaa ataaataaaa taacagcaca cctataaaat
      901 acaagtgtgc tgttcataaa cagattttat aaaaaaataa ttcctaagta gagattaaca
      961 tgctttctca tactctcata tataatgtgt ctaaaaatat taataaaaat gttttaattg
     1021 ttttaactta cttggatgtc ttaattttct tattgcttta gcttctatct gtcttattcg
     1081 ttctctggta actccaaata cctttccaat ctgttctagt gttttagggt catcatcatc
     1141 aattccaaat ctcattctta aaacttgctg ttcttgctct ccaagacctg taagtagttc
     1201 ttctatcttt tcttttaaat tatgctgttc aacttcgtgt attacaacat ctttaaaatc
     1261 agcatctgat ggtataaatt caactaaact actatcctca tcttctttta atggagtatc
     1321 caaagataca acatttttat ctcttcttaa taattccaac actttgtcaa cttctaagcc
     1381 acatgcatct gcaatctcat ctatagttgg ctctcttaat aatacattta aaagttcttg
     1441 tttctttttc tttacaaaat ttattctctg atgaagatgt ataggtatcc taatagtatt
     1501 ttcgcaatcg tcgatatatc ttgttatact ttgttttatc caccaagttg cataagtgct
     1561 aaatttgtat ccttttttat aatcgtactt ttctacagct tttataagtc ctatatttcc
     1621 tgcttgaatt aaatccaaca tatcaatact atctctttta tatctctttg ctatgctcac
     1681 taccaaccta taatttgaat ttataaattt ttcttttgct actgaagatg agttgattat
     1741 ttccttagcc agctctacct cttctcctgc tgacaacatt ttgtattcct ctatttcctt
     1801 taaatacatt ttcatcgcat ttgatacatt tgatgaaccc acacaaatat aattttcata
     1861 attattttct tttttagtat ccataatcaa accccttcta ttcatagaat ttgctaaaac
     1921 aaaaataaat aatttaaacc tacataatct acaattacat aatatcccat tctttaaatg
     1981 aattgttttg tatattatgt atacaaattt ataaaaacta tacctataat attattctac
     2041 ttctaacagc aatatcctcc ttatatatat aatttatttt attatatgtt gttatattct
     2101 tagttttttg aatgatatat gtctaaaaaa agactgttta ctaaacagtc tttttttata
     2161 tatatgctca atatttaatt ttcatgatga tgattacatc cacatccaca attttcatca
     2221 tggtgatgat gttcttctaa atcttttacc tgttgttcca tttcatgaaa ctcttttacc
     2281 attatatcat aagttggaag agctgcctca gtatcgtatt cttcccctct ccaatcagcg
     2341 tacatcatag catctccatt agttaaaacc aatctacctg acatagttat attatccact
     2401 tcttctaaaa attctatttg tttttgtaaa acttctcctt ctaactctac atcttcatct
     2461 aaacattgca ctatcattac aggtgcataa taatcttctt catctttaac atttacaaca
     2521 atatctaaaa ttccttctgc accttcttca aattctgcca actcaacatt tgtatcaatc
     2581 atatcttgag gtactaataa atcttctatt aaatatttta ttactctatc ttttactaat
     2641 tcttttgaca tttatttttc tccttccgat tctataacat tatcataatc atttctatat
     2701 tatagtatac tacattaatt gttttttcaa tctctcacaa aaattatttt tttattatct
     2761 tccttatatt ccctttttta ttacaaagtt gtaatcgcat tgatttaaaa aatagtttat
     2821 atttagtata atagaaatgt agcacatatt tttattcaat atattaataa aaaaatagat
     2881 tgaaaatgta atgtatgtta aatctaggag gaatattatg aagtttaaaa aacaaattag
     2941 ttctattgtt gtgtctacta tgcttgtact tgggagtata aacctttctt atgcagatgg
     3001 tacaaatgta gttacacttg gagctaactt atcagagtct caaaagcagc aaatgcttaa
     3061 ttactttgga gtaaaaaaag accaagtctt agttttagat gtaacaaatg cagaagaaag
     3121 acagtattta caaggtgttg caacagaggg tcaacttgga aaagttacta tctcttgctc
     3181 atacgttgaa cctactaaaa aaggaaatgg aattaatgtt aaaacagcaa acttaacttg
     3241 ggtaactagt tcaatgattg cttcaaccct tacaacagct ggtcttgaag atgcaaatgt
     3301 tattgctgct gctccatatc ctgtaagtgg tactggagca ttgacaggaa tcatgaaagc
     3361 atttgaggat gcttcaggaa agaaacttga tgaaactaag aaagaaattg cttctgaaga
     3421 attggtagtt acaggtgact taggagatga tatagggcaa gaaaaagcaa caggtgtaat
     3481 gaatgatata aaaacagaaa ttgtaaagaa tggtacaaaa gataccaatc aaatagcaaa
     3541 tacaataaat aatgttgtaa ataattacaa tattactatt acaccagaac aaaaagaaca
     3601 aattaaaggt gtaatgaaaa aaatagctga ccaaaattac gattacaata gcatgaaaaa
     3661 tacactagat aatgtatcag ataatgtaaa tgaacaatta aagaaattag gtgaaagtgt
     3721 taagggttct ggtatactag atactattgg tggatggttt agtggaatag gagactggtt
     3781 ctctggttta ttctcaggcg gagataaaaa agatttggga atcttaaata acactaatga
     3841 tgagtctctt ggctctgatg ctgtaataaa ttctacagaa ggtgttcaaa taaatccaca
     3901 aaataatact aattctaaca atgataatga tacaaatagc tcaaaaaatg atacttcaag
     3961 taataatgaa aataacgata gttctcaaac aaatgaaaac aacacaacaa ataattcaga
     4021 aaatcaatca aataataatg actcagttgg tttctttgaa aaaataaaaa attggctttc
     4081 aggcttattt tagaaattaa acaaataaaa agaattgcct aaaatggaaa ttttctataa
     4141 aaggcaattc tctttattta caataaattt ttattactca ctcatttttt tagatttttc
     4201 tatacatgca catattgctt ttatcacaga agctctaaaa ccttcttctt caagtacttt
     4261 aactgcttct atagtagttc caccaggtga acataccata tcttttaatt caccaggatg
     4321 ttttcctgtc tcaagtacca tttttgcaga acccataaca gcctgtgatg caaacttata
     4381 tgcttgtggt cttggcattc ctgcaattac tgctgcatct gctatagctt ctataaataa
     4441 aaatacatat gctggtgcag aaccacttgc accaattaca gcttctataa gatactctgg
     4501 tactacctca gtatttccaa aagaattaaa tacttctgta actacttcta agtcttcatt
     4561 gtttatattt ttatttatag aaagagaaga catggcttca tttacaagag ctggagtatt
     4621 tggcatagtt ctaactattt ttttatcttc tcctataatt gactctatat cctttataga
     4681 ttttcctgct gctattgtaa ctataatttt attgtcatct ataaaatctt ttatctcttc
     4741 caaaatatca tcatatatat ctggtttaac agccacaatt actatatcag aggttctagt
     4801 tacttccttt gaatcttttg tagtatttat tccaaaattt gcatatattc tatcaagagt
     4861 ttcttgacta tatgctgatg ctataaccat attaggttca actaattttg aatttactat
     4921 tccccctatc atagcgcttg ccatatttcc tgcacctatg aatccaattt ttttcacttt
     4981 agtacctcct tgttaactaa tagtaatcgt taaaatttaa gcttctttaa ctgcatcaga
     5041 cttttcaaat ggatttggta tacttactac caaaattttc actaccttat tagtatagtt
     5101 gacccaatta tgattgttct tttcactatt atagtgtatt gtgtctcctg gatacatttc
     5161 tatttgctca tctcccaaaa acactgtaag agtaccctct aatacataca caaactcctc
     5221 accttcatgt acgtaacaac aaatttcctc actactctta cttggaagaa tttcaattaa
     5281 tcttggtaac attgtttttt cctttaaact agatgataaa tgataatgta taaatgttga
     5341 gttttctaca tcaaatactt ctttttcata acttcttaat acagctcttt tatgctcttt
     5401 tggcttcata aaaaagtaag ttaattctac atctagtaca cttgctatct tgcctaagga
     5461 atctgttgcc acacttgtta atcctctttc aagttgtgat aaaaaaccaa ttgacaagtt
     5521 tgttttttca ctcatatcct tcaacgtcat ttgcttttga gttctgagtt gctttatttt
     5581 tgctcctatg tccttattca aaaccatcac ccctaaataa ttttaatttt ttcataatat
     5641 aaatacaaaa atataaatat aggtactgaa cctatcttta tttcattttt aaaaaatttt
     5701 ataagtatta ctataattta ttagtctttt tttgtctaca tttttacgat tatttacgat
     5761 ttatttttca cacatgcata tttaatttcg ccaactaaat atacattttt tataagcatt
     5821 tactctttat ataataaaac ttaagttatt cacacagtct tctttcactt taattactaa
     5881 aaattcaaat tatatcatta ttatttctac acattattac atactttagt acaattataa
     5941 cataatttta caatttaatg atatctattc aatgtctttt tttactctac aacatatttt
     6001 attttagagt ttaatactat atatattttt tatatacagc cttgtcattt tttagattgt
     6061 caagagttat tgaagtattt tatgtagatt tatattttat tttctaattt ctcatttaac
     6121 aagaattgct tatgataaaa aataatatca tctcaataag attcttgtaa atatatctat
     6181 attctaaata taatttcttt ttttgtcaaa atttcttcat tctttaataa ttaatttatt
     6241 acttataaaa taaactaatt atctatacaa attttataat ttttaataaa atacagaaaa
     6301 aaattaattt ttatagc
//
LOCUS       DACTZW010000141         6072 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.143, whole genome shotgun sequence.
ACCESSION   DACTZW010000141 DACTZW010000000
VERSION     DACTZW010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6072)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6072)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6072
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.143"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            <1..704
                     /locus_tag="JAM15_18205"
     CDS             <1..704
                     /locus_tag="JAM15_18205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009319957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAT6800179.1"
                     /translation="SKSIRQNGTKNNRGNTSSSMGQKAGSAVGAVLDTKNKVKDKATA
                     VKENIKDMPTQTVYAVHSAKEKAKSSMSDFKRGVVQEKENRQSGRLEKQQLHRQNIAD
                     KRMELQKAQEARQAGKKTDGSATSGATRPHERPATATKQNIEKQQEVKRPATASTIKN
                     DEPSKKNAIKERPLSSGGSSAKTVNQEIARQNYKAERVTKTQTTTTQKQTQQQTQQNT
                     EKNKRTLFKKGQKKK"
     gene            701..1708
                     /locus_tag="JAM15_18210"
     CDS             701..1708
                     /locus_tag="JAM15_18210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase P60"
                     /protein_id="HAT6800180.1"
                     /translation="MKLRHIAIVGSLFPILFSIVLFFGVLISAEDDDEGNSYSSNYAG
                     MNLSAEVLKHQPMVEKYAKENGISEYVNVLLAIIQVESGGTAEDVMQSSESLGLPPNS
                     LDTESSIKQGCQYFASLLSSCKNQGISDINVVIQSYNYGGGYVGYVAGNGKKHTFNLA
                     ENFARDKSSGQKVTYTNPIAVAKNGGWRYGYGNMFYVELVNQYLVVNQVSGELAQKIM
                     NEALKYQGWKYVYGGSNPNTSFDCSGLTQWCYGKAGISLPRTAQMQYDATQHIPLSQA
                     KAGDLVFFHSTYNAGSYVTHVGIYVGNNQMYHAGDPIGYTDLNNSYWQQHLIGAGRIK
                     Q"
     gene            1724..2617
                     /locus_tag="JAM15_18215"
     CDS             1724..2617
                     /locus_tag="JAM15_18215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAT6800181.1"
                     /translation="MFKKKEKPVKEKKVRTVKVGTHKKSVIALWVVLIASVSFGVYKN
                     FTAIDMHTVHETETIQLRLNDTNGIENFVKNFCKSYYTWDNSKEAIEARAQAISNYLT
                     KELQDLNLDTIRTDIPTSSIVTNVLIWDIEQSGTDDFIATYEVDQQIKEGEQTTNVKA
                     TYTVKVYVDKDGDMVIVQNPTLAPAMEKSDYEPKAQEADNSVDADTTADATAFLETFF
                     KLYPTATETELAYYVAGNALEPINGDYLYSELVNPVFTADEDNIKVKVAVKFIDNHTK
                     ATQISQYELTLHKDGNWKIIG"
     gene            2750..2989
                     /locus_tag="JAM15_18220"
     CDS             2750..2989
                     /locus_tag="JAM15_18220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008791134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HAT6800182.1"
                     /translation="MPMKKGQHIFGTVKVGEKGQIVIPKEARQIFDIKAGDTLLVLGD
                     EEQGIAIVKADVMKELAVKILKGLGKLSNGIDDEK"
     gene            2979..3596
                     /locus_tag="JAM15_18225"
     CDS             2979..3596
                     /locus_tag="JAM15_18225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005951992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HAT6800183.1"
                     /translation="MKNNIMLILPIAFILDLLIPFILAPTYRGYSHLTQVMSVLGNSK
                     APLHNVYNTWLVIFGMTLAVINFKVYAVVSKGSRLIAIILFIVLLIYAIGGCILSGLF
                     SVGEVKSLNTLSEKIHGYGSVVGFMCLSFAPLLLGIYAYKINDIKFSFFCIGCFILAI
                     LCFSCFVMGDKPNFRNTFLAFEGLWQRLSLLFMYFPLGCLILFET"
     gene            3679..3908
                     /locus_tag="JAM15_18230"
                     /pseudo
     CDS             3679..3908
                     /locus_tag="JAM15_18230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060191.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3924..4394
                     /locus_tag="JAM15_18235"
                     /pseudo
     CDS             3924..4394
                     /locus_tag="JAM15_18235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892232.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            4607..5464
                     /locus_tag="JAM15_18240"
     CDS             4607..5464
                     /locus_tag="JAM15_18240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAT6800184.1"
                     /translation="MYKEVGISSNNVPITLSIWYTERSSPTIVFLPGTMSHPLMYENF
                     LCGLSERGFNIIGIHYLSHGKSPKIKKNYTMEDLLHNVYDATTYGIENFGENIAVMGS
                     SQGGILAAMAAGRDTRLKAVFPHNIMLTTLKETMSLTKYPAWSHRFMGLIQLGFRVGG
                     KLLPNYKVPGDAYLDYDRVFYSEQAKQDCLNDPMLLPYYPLRFVASLFNADLSCLENG
                     AIQCPVILITAKGDPLFSFDYTNKVFDLIHVPKKELLTLELNRHMIFNEDTDTTINAL
                     EATLHKYLG"
     gene            5536..>6072
                     /locus_tag="JAM15_18245"
     CDS             5536..>6072
                     /locus_tag="JAM15_18245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAT6800185.1"
                     /translation="MSLPRFTEQEKEIINSKLLIEGEKLFSLYGLKKVTVDDLAAAVN
                     ISKGSFYAFYPSKEHLYVEINFRLQKELFTSIETTVKKKKYKNHRDLAKDVIMLSLTG
                     VITSPILSQIDLSLMDYLQRKISSDIFENHMYSDIRILEILEGLGVVFLVPHTVIIKS
                     LYSVLSCLEQFKEDEELNM"
BASE COUNT         2061 a         1053 c         1297 g         1661 t
ORIGIN      
        1 gttcaaaatc tatacgccag aatggaacaa agaacaatcg tggaaataca agctccagca
       61 tggggcagaa agcaggttca gccgtgggag ctgtccttga tacaaagaat aaggtcaagg
      121 acaaggcaac tgctgtcaaa gaaaatatca aagatatgcc gacacagacc gtttatgcgg
      181 ttcactctgc taaggaaaag gcgaagtcca gtatgtctga tttcaagcgt ggcgtggtgc
      241 aggaaaagga aaaccgccag tctggacgtt tagagaaaca gcagcttcat agacagaata
      301 tcgctgacaa acgtatggag cttcaaaaag cacaagaagc aaggcaggca ggtaagaaaa
      361 cggacggatc agcgacaagc ggagctaccc gtccccatga aagaccagcc acggctacca
      421 aacagaacat agaaaaacag caggaagtca aacgccctgc cacagcttca acgattaaga
      481 atgatgaacc tagcaagaaa aatgctatca aagaacgtcc gctatcttct ggcggttcat
      541 cagcaaaaac ggtcaatcaa gaaatcgcaa gacagaatta caaggctgaa cgtgttacga
      601 aaacgcagac aactaccaca cagaagcaga cacagcagca gacacagcag aataccgaga
      661 agaacaaacg aaccctattc aagaaaggac aaaagaagaa atgaaactaa gacatatcgc
      721 tattgttggc agtctgtttc ctatcctctt ttctatcgta ttattctttg gggttctgat
      781 tagtgccgag gacgacgacg agggcaacag ctattcttct aattatgcag gaatgaacct
      841 atctgccgag gtattgaaac atcagcctat ggtagaaaaa tatgccaaag aaaacggtat
      901 ttccgagtat gtcaatgtgt tgctggcaat catacaagta gaaagtggcg gtacagccga
      961 ggacgttatg caaagttcgg aaagtttggg actaccgcct aattccttag atacagaaag
     1021 ctcaatcaag caggggtgtc agtattttgc gtccctgctt tcttcctgca aaaatcaagg
     1081 tatcagtgat ataaatgtcg tgatacagtc ctataactat ggcggtggct atgttggtta
     1141 tgtggcagga aacgggaaaa agcatacatt caaccttgcg gaaaacttcg caagggataa
     1201 atcgagcggt cagaaagtaa cctatacgaa ccctatcgct gtggcaaaga acgggggctg
     1261 gcgttatggc tatggaaata tgttctatgt ggagcttgtg aaccagtacc ttgtcgtcaa
     1321 tcaagtatcg ggcgaactgg cacaaaagat aatgaatgaa gcgttgaagt atcaaggttg
     1381 gaaatacgtg tatgggggca gtaacccaaa cacttctttt gattgtagcg gactgaccca
     1441 gtggtgttat ggcaaggctg gtatctcttt accgagaacc gcacaaatgc agtatgacgc
     1501 aacacagcat atcccactgt cgcaggcaaa ggctggcgat ttggtctttt tccacagtac
     1561 ctacaatgca ggaagctatg taacccatgt cggtatctat gtaggaaata atcagatgta
     1621 tcatgcaggc gaccctatcg gatataccga ccttaataat tcgtattggc aacagcactt
     1681 gattggtgct ggaagaataa aacagtagaa aggattggaa accatgttta aaaagaaaga
     1741 aaaaccagta aaagaaaaaa aggtgcgtac tgtcaaggta ggcacacata agaaatctgt
     1801 gattgcatta tgggtagtgc ttatcgcaag tgtgagcttt ggagtttata agaactttac
     1861 cgctattgat atgcacaccg tacatgaaac agaaacgata cagcttagat taaatgacac
     1921 caacgggatt gaaaatttcg tgaagaactt ctgtaagtcc tattacacat gggacaacag
     1981 caaggaagct atcgaagcaa gggcgcaggc aatcagtaac tatctgacaa aggaattgca
     2041 ggacttgaac cttgatacca taagaacaga tataccgacc agctccattg ttacaaatgt
     2101 cttgatttgg gatatagaac agtcgggaac ggacgatttt atcgctacct acgaagtaga
     2161 tcagcagata aaagagggag aacagacaac aaatgtcaaa gcaacctata ccgtcaaagt
     2221 atatgtagat aaagacggcg atatggtaat cgtacagaac ccgacccttg ctcccgctat
     2281 ggaaaaatcg gactatgagc caaaggcaca ggaagcggac aacagcgtgg acgctgatac
     2341 cacggcagac gctacggcgt ttttggaaac attcttcaag ctgtacccta cggctacgga
     2401 aacggagctt gcctactatg tggcgggaaa tgcccttgaa ccgataaacg gggactatct
     2461 ctattccgag cttgtcaatc ctgtatttac ggctgacgag gataacatta aggtaaaggt
     2521 tgctgtgaag tttatcgaca atcatacaaa ggcaacgcag atttcacaat atgagctgac
     2581 gcttcataag gacgggaact ggaaaatcat aggttaatca ataaggcgtg tatatctgca
     2641 aaggggtaca cgcttcctta aatttgacaa actacactcc ttatgttata ctttttttgt
     2701 aagtatgaaa agtataacaa aaataaaaag ttagaattga ggtgtaatta tgccaatgaa
     2761 aaagggacaa cacatatttg gaacggttaa agtaggagaa aaaggacaaa tcgttattcc
     2821 aaaagaagca cgacaaattt ttgatattaa agcaggagat acattattag tgctgggcga
     2881 cgaagaacag ggaatagcta ttgtgaaagc agatgttatg aaagaattag ctgtgaaaat
     2941 attgaaaggg ctgggtaaat taagcaacgg tatagatgat gaaaaataac attatgctta
     3001 tacttccgat agctttcatt ttagatttac ttattccttt tatcttagct cccacatata
     3061 gaggatatag tcatttaaca caggttatga gtgttcttgg aaatagtaaa gccccgttgc
     3121 ataatgtata taatacatgg ctggtaatct ttggaatgac tttagcagta atcaatttta
     3181 aggtatatgc ggttgtttca aaggggtcaa ggctaattgc aataatcctt tttatagtat
     3241 tgctgattta tgcaatcggc ggctgtattc tttctggctt attctctgtt ggagaagtaa
     3301 aaagtcttaa tactctttca gaaaaaatac atggttacgg ctctgttgtt ggatttatgt
     3361 gtttgtcatt tgcaccgctt ctgttaggaa tttatgcgta taaaataaat gacataaaat
     3421 tttcattttt ctgcattggg tgttttatat tagcaatatt gtgtttttca tgttttgtta
     3481 tgggagataa acctaatttt aggaatacgt ttttagcatt tgagggttta tggcaaagat
     3541 tatctttatt atttatgtat ttccctttag ggtgtctgat attgtttgaa acatgacagt
     3601 tttcaatgta taccatatca aaagataaat aaattcagtt atttagccgt agctaaaaaa
     3661 taggattgga gtgataccat gataagacta aaaaagcagg atattaaaaa atgctgaaac
     3721 aaggggcaaa attgagtgat gttccactat cggaaattca agaaaacata gaagccacca
     3781 ttgatgaagc tatgaacagc accgacccag aagtacaggc aaatttcaaa aaatattttg
     3841 gcaacaaaag acccacgcca gaggaatata tttatacaat gacaaagaaa tcaagattta
     3901 aagtatgaga gcctttattt actacctacg aagtagatca gcagataaaa gagggcgaac
     3961 agacaacgaa tgtcaaagca acttataccg ttaaaatcca tgtagataaa gatggcgata
     4021 tggttatcgt tcagaaccct acccttgcac cagcgattga aaaatcagac tatgagccaa
     4081 aggcacaaga agccgacgca agcgtggacg cagataccgt caatgacgct accgcatttt
     4141 tggaaacttt ctttaagctg tatccgacag caacagaaaa agaacttgct tactatgtag
     4201 ctggcaatgt gcttgaacct atcggcaagg actacctcta ttcagaatta gtcaatcccg
     4261 tgtttacggc tgacggggac aatgtgaaag tcaaggttgc cgtgaagttt attgacaatc
     4321 agacaaagac aacgcaggta tcacagttta agcttgtgct acataaggat aacaactgga
     4381 agattattat gtaagatatt ttgttggcag gctctatttt cggatatagt ctgccttttc
     4441 tgtagcaaat gtgctgcact aacaagcgat ttcattgtat tttaagcaat taaatctttc
     4501 ttgacaattt tatcttaaat catatattta tggatattga ctttctgctt acaataagtt
     4561 aaaatatgac tataaaacca aattagtcat ataggaggta tgtggtatgt ataaagaagt
     4621 tggtatttct tcaaataatg ttccgataac actttctatc tggtatacag aaagaagtag
     4681 tcctaccatt gtttttttgc cgggtactat gtcacaccct ctcatgtatg agaattttct
     4741 atgtggtttg agtgaaagag gatttaatat aataggcatt cactatcttt cacacggaaa
     4801 aagccctaaa atcaaaaaaa attatacaat ggaagatttg ctgcataatg tatatgacgc
     4861 aacgacttac ggaatagaaa attttggtga aaacatagct gtcatgggtt ccagtcaagg
     4921 tgggatttta gctgcaatgg cggcgggtag ggacacaagg ttaaaagccg tttttccaca
     4981 taatatcatg ctgactacat taaaagaaac tatgagctta acaaaatacc ccgcatggtc
     5041 acaccgtttt atggggctga tacagttggg ctttcgtgta ggtggaaaat tgctgcctaa
     5101 ctataaggtt ccaggagacg cttatttaga ctatgacaga gtattttata gtgaacaggc
     5161 aaaacaagat tgcttaaatg accctatgct tttaccctat tatcctttaa gatttgtcgc
     5221 cagcttattt aatgctgact tatcgtgctt ggagaatggg gctatacaat gtcctgttat
     5281 tttaattact gccaaaggcg atccgctttt tagctttgat tataccaaca aagtatttga
     5341 tttaattcat gtaccgaaaa aggaattact tactttagag cttaatcgtc acatgatttt
     5401 taatgaggac acggacacta caataaacgc attggaagct accttgcata aatatcttgg
     5461 atagtatatt gattatataa tcagtaaatg ttatactttt catgacgata aaaacatttt
     5521 agtcataagg gggttatgag tttgccacga tttacggaac aagaaaaaga aatcataaac
     5581 agtaaacttt tgatagaggg agaaaagctg ttttcattat acggcttaaa aaaagtaaca
     5641 gttgatgatt tagcagctgc tgtaaacata tcaaaaggtt cattctatgc tttttatccc
     5701 agtaaagaac atctatatgt ggaaatcaat tttcgcttac aaaaagagtt atttacaagt
     5761 atagaaacaa ctgttaaaaa gaaaaagtat aagaaccata gagatttagc aaaggacgtt
     5821 attatgctaa gtttaacggg ggtgattact tcgcctattc tttcacagat tgatttatct
     5881 ttaatggact atctgcaaag aaaaatatcg tcagatattt ttgaaaatca tatgtacagt
     5941 gatattcgta tattggagat actggaaggt ttaggggttg tatttttggt tccgcatacg
     6001 gttatcataa aatccctgta ttctgtttta tcctgtttgg aacaattcaa agaggacgaa
     6061 gaattgaata tg
//
LOCUS       DACTZW010000142         5860 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.145, whole genome shotgun sequence.
ACCESSION   DACTZW010000142 DACTZW010000000
VERSION     DACTZW010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5860
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.145"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            25..1332
                     /locus_tag="JAM15_18250"
     CDS             25..1332
                     /locus_tag="JAM15_18250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800186.1"
                     /translation="MKEIADAITSEYLSYGINEDISIYEGRFCIYLDKKYRCNGKIYY
                     KMTPPISISFKAEIGCVEDIDNEDDNLVLDYDNAILEVHGYKIISITINTLSEFSVEG
                     YINDDCIKSKNSYVEYVDFNIINLDKIPGKLIKYNDKVYAGRIEFDINDYVVTIDKRY
                     DYRKELKSELKSKSGAIITHIGRIRRKDGRIFRTNNIINLLDRISTALSFMCGRYVGF
                     CLAKGYRSGNEVYRIWNENQISPFRYAPTWSDTLSNYHNMEKYISLMCKKLEDFYYGS
                     AIKSVVDWYIESLGSATMENNIISVQIALETLSYVILVEQSKILTDEAFDCNLASKNV
                     RLLLDTCKIPYGKHELNIFDNIIKNKFDDGVDLVIYLRNSIVHPSRKTHRAVLEVEDI
                     WNIISIGTRYIELVLLFILGYRGEYSNRLVERCYGEVEVVPWN"
     misc_binding    1418..1680
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1806..2609
                     /locus_tag="JAM15_18255"
     CDS             1806..2609
                     /locus_tag="JAM15_18255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HAT6800187.1"
                     /translation="MKNILKKVGIFTIMLGLLGGVVGCSKPDNEKDKDASKESKKEVV
                     VGFDNTFVPMGFLDEKGDTVGFDVDLAKETFKRLGMEVKFQPIDWSMKETELNDSKTV
                     DVLWNGYSITDERKKIVSYTEPYLQNKQIIVTLSDSKINSKADLKDKEVGTQQGSTAL
                     DAVEKDKDFMNSLKGGAPVLYDTYDKALRDLEIGRTSAVVGDEVLIRYYMGQKGEDKY
                     KVLKDDFGLEDYVVATSKENPELCEKINKTLKEMKKDGTFDKIYDKWFK"
     gene            2647..3258
                     /locus_tag="JAM15_18260"
     CDS             2647..3258
                     /locus_tag="JAM15_18260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAT6800188.1"
                     /translation="MLQGLEIVIAMFCITLIVSIPLGIGVAFLRLSKNKLVSGITQCY
                     ILIMRGTPLLLQMIVIFYGLPLLGIVFDRFTAGVVAFFLNYAAYFAEIFRGGIQSIDR
                     GQYEASKVLGFDKFTMYKRVIFPQVFKRILAPISNEVITLVKDTSLVYILGLNDILRI
                     SQIAMNREASLLPLFEAGAIYLIFVAILTKGFELLEKKYSYYR"
     gene            3290..3961
                     /locus_tag="JAM15_18265"
     CDS             3290..3961
                     /locus_tag="JAM15_18265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAT6800189.1"
                     /translation="MLKIKNLNKSFKKNRVLKDISFELEEGQIGVLLGKSGAGKTTIL
                     RCINGLEEFDSGEIIIDNEVIKNKRDMAKIRGKIGMVFQNFNLFPHMTVLENIIESPV
                     NVFKVPRKEAEERARELLRLVDLEDKLNSYPFELSGGQQQRVAIARSCALMPKVLCFD
                     EPTSALDIDTIQRVVNIMNRLKDKGMTILIITHDVVFSNNVADKIISIKDGIVENVQI
                     KEKIV"
     gene            4260..4622
                     /locus_tag="JAM15_18270"
     CDS             4260..4622
                     /locus_tag="JAM15_18270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HAT6800190.1"
                     /translation="MIKLYGYTKCSTVKKAKNWLKENNLEFEDIDMVQNPPSKEELKS
                     IYKTSGYDIKKFFNTSGMKYRELGLKDIVKTESDDKLLEILVSDGMLIKRPLLLDGKN
                     VLLGFKEDVWKSTLLKED"
     gene            5058..5759
                     /locus_tag="JAM15_18275"
     CDS             5058..5759
                     /locus_tag="JAM15_18275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4253 domain-containing protein"
                     /protein_id="HAT6800191.1"
                     /translation="MSIEDLYDFECVPLNNEIDIDVLFEKMIEDGKEKEYTPIIVIDE
                     KVGLLRKNIDMITKEYGSLENYREYCLTKYNEIDVNQFFDFRKSEISELLKELIDLED
                     DFYDYKHFRTIMNIDIFHEYNKVYIAKIPTIKPYEVFAYIPIGGFNDCPRDEEHIAIA
                     KYWYEKHGIFPIAIGCDTVQYSVKNLTKDGKKFDDLCIELVFYCEDIIIQGYETLKAL
                     KDVLKRSTIVLFWWD"
BASE COUNT         2346 a          531 c         1030 g         1953 t
ORIGIN      
        1 ataaaagcaa aggtgggaat aaaaatgaaa gaaattgctg atgctataac atcagagtat
       61 ttaagctatg gtatcaatga agatattagt atctatgaag gtagattttg catatattta
      121 gataaaaaat atagatgtaa tgggaaaatt tattataaaa tgacacctcc aatatctata
      181 agttttaaag cagagatagg ttgtgttgaa gatatagaca atgaagatga caatttagtt
      241 ttggattatg ataatgctat tcttgaagtt catggatata aaattatttc tataacaata
      301 aatactttaa gtgaatttag tgtagaaggc tatatcaatg atgactgcat aaaatctaag
      361 aactcctatg ttgaatatgt agattttaat ataataaact tagataaaat acctggaaaa
      421 ctcattaaat acaacgataa agtatacgca ggtagaattg aatttgatat aaatgattat
      481 gttgtaacta tagacaagcg atatgattat agaaaagaat taaaatcaga attaaagtct
      541 aaatctggag caataataac tcatataggt aggattagga gaaaagatgg tagaattttt
      601 agaacaaata atataataaa tcttttagat agaatatcaa cagctttgag ttttatgtgt
      661 ggaagatatg taggattttg tttggccaaa ggatatagaa gtggtaatga agtttataga
      721 atatggaatg aaaatcaaat atctcctttt agatatgcac caacatggtc agatacactt
      781 tcaaattatc ataatatgga aaaatatata agccttatgt gtaaaaagct agaagatttt
      841 tattatggtt ctgctataaa gagtgttgtt gattggtaca tagaatctct tggaagtgct
      901 accatggaaa acaatataat atctgtacaa attgcacttg aaactttgtc atatgtaatt
      961 ctagtggaac aaagtaagat acttacagat gaagcatttg actgtaattt ggcatctaaa
     1021 aatgtaagac tcttacttga tacatgtaag ataccatatg gtaaacatga attaaatata
     1081 tttgataata taataaaaaa taaatttgat gatggagtgg atttagttat ttatttaaga
     1141 aatagcatag ttcatccaag tagaaagact catagagctg tgttagaggt tgaagatatt
     1201 tggaatataa tttcaatagg aacgagatat attgaacttg ttttactctt tattttaggt
     1261 tatagaggag aatattcaaa cagattagta gaaaggtgtt atggtgaagt ggaagttgta
     1321 ccttggaact agatttttat atttatttta aaatatatat tgacatatat tgccttatgc
     1381 tataaaatca atattataat aataattcag aataacatta aatgctaaga aaagaaatag
     1441 taaaggtagt taatcttaaa cagagagttt ccgattggtg agaggagcaa tagattttac
     1501 tttgaacaca tctttgagca ggactctgaa agagtagaaa tactttatta ggagatttcc
     1561 ggaatccttg cacccgttat agtgctagag tataataatt ttattgtact taaagaggtt
     1621 agtgtcgtga ggcattaatg aacagaggtg gaaccacgag agttaactcc cgtcctctag
     1681 cagaagctag aggcgggagt tttttaatat aattttttaa gcgcgcagag aattatattg
     1741 caatagatac actttttaaa aaataatcaa aatattttaa aaattaaaag gcgagggaga
     1801 atattatgaa aaatatatta aaaaaagtag gaatatttac aattatgtta ggtttattag
     1861 gtggagttgt aggttgttca aaaccagata atgaaaaaga taaggatgct tcaaaggaat
     1921 ctaaaaaaga agtagttgta gggtttgata atacgtttgt accaatggga tttttagatg
     1981 aaaagggaga tacagtagga tttgacgtag acttagctaa agaaacattt aaaagacttg
     2041 gaatggaagt taagtttcag cctatagatt ggtcaatgaa ggaaactgaa ttaaatgatt
     2101 caaaaactgt agatgtatta tggaatggat attctataac agacgaaaga aagaaaatag
     2161 tatcatatac agaaccatat ttacaaaata aacagataat agttactcta agtgattcaa
     2221 aaataaattc aaaagctgat ttaaaagata aagaagttgg aacacaacaa ggttcaacag
     2281 cacttgatgc agtggaaaag gataaagatt ttatgaatag cttaaaaggt ggagcaccag
     2341 ttctttatga tacttatgat aaagcactta gagatttaga gataggtaga actagtgcag
     2401 ttgttggtga tgaagtttta attagatatt atatgggaca aaagggtgaa gacaaataca
     2461 aggtattaaa agacgatttt ggattagaag attatgttgt agcaacttct aaagaaaatc
     2521 cagaactttg tgagaaaata aataaaacat taaaagaaat gaaaaaagat ggaacttttg
     2581 acaaaattta tgataagtgg tttaaataga agataagtta gctgttaaga agggggcact
     2641 aaaggcatgt tacaaggttt agagatagtt atagcaatgt tttgtataac attgatagta
     2701 tcaattccat tggggattgg agttgcattt ttaagattat caaagaataa attagtaagt
     2761 ggtattacac aatgttatat attgataatg agaggtacac ctttactttt gcaaatgata
     2821 gtcatatttt acggattacc tcttttagga attgtatttg acagatttac agctggagta
     2881 gtagctttct tcttaaatta tgcagcatat tttgcagaaa tatttagagg tggaatacag
     2941 tcaatcgata gaggacaata tgaagcttca aaagtactag gatttgataa atttactatg
     3001 tataagagag taatctttcc acaagttttt aaaagaatac tagcacctat ttcaaatgaa
     3061 gtaatcacat tagtaaaaga tacatcttta gtatatatat taggattaaa tgatatttta
     3121 agaatatctc aaatagcaat gaacagggaa gcaagtctgt taccattatt tgaggcagga
     3181 gcgatatatc ttatatttgt agctatactt actaagggat ttgaattact tgaaaaaaaa
     3241 tattcttatt atagataaag ttacaatatt ataggaggag gttttttata tgttgaaaat
     3301 caaaaactta aataaatcat ttaaaaaaaa tagagtactt aaagatattt cttttgagtt
     3361 agaagaaggt cagattggag ttttacttgg taagtctggt gcaggaaaga ccacaatatt
     3421 aagatgtata aatggtcttg aagaatttga tagtggagag attataatag ataatgaggt
     3481 aataaaaaat aagagagata tggcaaaaat acgaggaaaa ataggtatgg tttttcaaaa
     3541 tttcaactta tttcctcata tgacagtcct tgaaaatata attgaatccc cagttaatgt
     3601 ttttaaagtt cctagaaaag aggctgaaga gagggctaga gaacttttaa gattagttga
     3661 tttagaagat aaattaaatt cttatccatt tgaattgtca ggaggacagc aacagagagt
     3721 tgctatagct aggtcatgtg cattgatgcc aaaagtcctt tgttttgatg aacctacttc
     3781 tgcacttgat attgatacta ttcaaagagt agtcaatata atgaatagac ttaaagacaa
     3841 aggtatgaca atattaataa ttacacatga tgttgtcttc tcaaataatg ttgcagataa
     3901 aattataagt ataaaagatg gtatagtaga aaatgttcaa ataaaagaaa aaattgttta
     3961 gagttttata aatataaact agggtagaat tttataatat aaataaaggg caagtaaaat
     4021 caaatatact atgccctttt gttatctcaa aatttaatct tatattttat gtttaagtta
     4081 cattataatt tataataaaa ataaaaggac tatttaaata tataatgtga ataaatgttt
     4141 aataatttga aatatgataa ttttttatgt tgaaagctta taatgattat gatataaatt
     4201 gattatagta tacaatttat gggtataaca ataaaaaatt agaaaggaat ttttataaaa
     4261 tgattaaatt atatggatat acaaaatgct ctactgttaa aaaagctaaa aattggctta
     4321 aggaaaataa tttagaattt gaagatatag atatggttca aaaccctcct agtaaagagg
     4381 agttaaaatc aatttataag actagtggat atgatataaa gaaatttttt aatacaagtg
     4441 gtatgaaata tagagaattg ggtcttaaag atattgtaaa aactgaatct gatgataaac
     4501 ttttagaaat attggtaagt gatggtatgc ttattaaaag accattactt ttggatggta
     4561 aaaatgtatt attgggcttt aaagaagatg tatggaaaag tactttgcta aaagaagatt
     4621 aggaagagat aggtgtgttg attaaaatta ttaattaata cacctataaa tttatgtatt
     4681 aaatctaatc tttataaata ttaattagca aattcaaatc aaaaaaattc atatcaacaa
     4741 atatattact tcttattaca aattatatca tatgttttat attaaaatat tataatatta
     4801 caacgaattg ttacaaaatt acttattatt aaccatgaac atttgttttg tgctatcata
     4861 tttatataag ggaattgtca taaaaaatat cttgttcata cagttttata tagaaaaaag
     4921 aaatgaatct tttctttata taagtatatt ttgtaaattg cctctatatt tatagtttaa
     4981 ataatagtgg ttttaaaaat ctgacaacaa aaataaaact ttcaaaaaat taaatctaaa
     5041 aagaatagga gataaatatg agtattgaag atttatatga ttttgaatgt gttcctttga
     5101 acaatgagat tgatattgat gttttatttg aaaagatgat agaagatgga aaagaaaaag
     5161 aatatacacc aattatagtc attgatgaaa aagtagggct attaagaaaa aatatagata
     5221 tgattactaa agagtatggt tctcttgaaa actatagaga gtattgttta acaaaatata
     5281 atgaaattga tgtaaatcaa ttttttgatt ttaggaagag tgagatttca gaattattaa
     5341 aggagctaat tgatttagaa gatgattttt atgattataa acattttaga acaattatga
     5401 atatagatat atttcatgaa tataacaaag tttacatagc taaaattcca acaattaaac
     5461 catatgaagt atttgcatac atacctattg gaggatttaa tgattgtcct agagatgaag
     5521 aacatatagc tattgcaaaa tattggtatg aaaagcatgg aatctttcca atcgcaattg
     5581 gatgtgatac agttcaatat tctgtaaaaa atttaactaa agatggtaaa aaatttgatg
     5641 acttatgtat tgaattagta ttttattgtg aggatattat tatacaaggg tatgaaacct
     5701 taaaggctct taaggatgta ttaaaacgct ctacaatagt gcttttttgg tgggattgat
     5761 attctatcat ttagatagta ttaaattgtt agtcaccaag aatcacttgc tttagttatg
     5821 gggagtgtgt caaactaggt ttttatacac agtgtagcat
//
LOCUS       DACTZW010000143         5779 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.146, whole genome shotgun sequence.
ACCESSION   DACTZW010000143 DACTZW010000000
VERSION     DACTZW010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5779)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5779)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5779
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.146"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            123..1358
                     /locus_tag="JAM15_18280"
     CDS             123..1358
                     /locus_tag="JAM15_18280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HAT6800192.1"
                     /translation="MGLIFIMFFGGFGTNWNMAKPVAIPSILMSSLGVIITAGVTGMF
                     CHMVIGTSLLEGLLIGAIAASTDAASVFAVLRSQKLNLKGSLASLLEVESGSNDPIAY
                     MLTLILLTLMNNSGVELIAPMVIKQIAFGLAIGFILAKLSVYILRHSNFEIEGFYTIF
                     ITAIAILSYAFSEYLGGNGYLSVYISGIIIGNSRIPLKKSLVHFFDGISWIMQIMLFF
                     MLGLLSFPSKLPNVFGIAMAISIFMIVIARPLATFIVLAKFKFSNKEKLFISWVGLRG
                     AASVVFAIYAVTQGVAIENDIFHIIFFIALLSVGIQGSLIPTVARKLDLVDDNTPVLK
                     TFNDYDGEISSKLIEVNVDEGNKWANKSIIDSNIPDDILIVMIKRKEQVLIPKGSTII
                     KTGDILVLSGDRIEELIQL"
     gene            1434..2246
                     /locus_tag="JAM15_18285"
     CDS             1434..2246
                     /locus_tag="JAM15_18285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAT6800193.1"
                     /translation="MFSIGMFSKINKITTKTLRYYEDIGLLKPEYVDEFTKYRYYTTE
                     QLPKLHQIITLKQMGLSLAEIKKAVENPEEVENILMNKEKEMLDVIKSEEYKIIKLRN
                     YLMNLKGEVNMNDVIIKSLPKVKVASMRKVLKGYDELFNLFPNVMAEEMMKTECTCAV
                     PDYCFNIYHDGEYRETDMDVEMCQATNDLKEDTDILKFKELDAVENAVCILHNGPYST
                     LGKTYADAFKWIEDNKYKVVGNPRESYIDGIWNKESEEDWLTEVQIPVKRIL"
     gene            complement(2586..3767)
                     /locus_tag="JAM15_18290"
     CDS             complement(2586..3767)
                     /locus_tag="JAM15_18290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAT6800194.1"
                     /translation="MKRQDSKGRNLRLGESQRKDGRYVYKYTDIFGKPQFVYSWKLVP
                     TDKTPAGKRDDISLREKEKQIKKDLDDGIDTVGGKMTVCQLYEKKNNQRKNIKRNTEL
                     GRQYLVNALESDPLGMRAIDTVKQSDAKEWAIRMNGKGYSYKTIDNYKRSLKASFYMA
                     IQDDCIRKNPFNSKLSDVLEDDTEAKVILTPEQEEKLLAFMETDNVYSKYRDEVILLL
                     ETGLRISELCGLTTHIDMLNRVINIDHQLLRDTEVGYYISKAKTKNGKRELPLTERAY
                     QALKRILKNRGKAQPLVVGGYSNFLFLNREGLPKVAGNYESMVRGLIKKYNKTHKDKL
                     PNITPHSFRHTYCTNMANKGMNPNTLQYIMGHANITMTLGYYAHGTFQSAKAELERLA
                     S"
     gene            complement(3748..3882)
                     /locus_tag="JAM15_18295"
     CDS             complement(3748..3882)
                     /locus_tag="JAM15_18295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAT6800195.1"
                     /translation="MYYFLEMSDTEIADIMNYTRGAVFKHRHRALETMKEILNEKTRQ
                     "
     gene            complement(3882..4172)
                     /locus_tag="JAM15_18300"
     CDS             complement(3882..4172)
                     /locus_tag="JAM15_18300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800196.1"
                     /translation="MKPSDFQKTIQCQFECKLKKVVKGIIWNYRKELRRRKNKEISFS
                     ELPDITVESLATWDDYETNYTIFNVCGIDIKVLDDELAEALKQLPEKNVTMY"
     gene            complement(4439..4669)
                     /locus_tag="JAM15_18305"
     CDS             complement(4439..4669)
                     /locus_tag="JAM15_18305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800197.1"
                     /translation="MIGLKRRDMNYIMKVGAKAQGVSVSEFRAMLQDTIDKTMESTDP
                     DVQANFKRYFGNKRPTPEEYIYTITKKTKVKV"
     gene            complement(4693..4884)
                     /locus_tag="JAM15_18310"
     CDS             complement(4693..4884)
                     /locus_tag="JAM15_18310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003064779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
                     /protein_id="HAT6800198.1"
                     /translation="MKKYEYVEINYNAKGVVFLCTDKHKEIIDSYAKTGYHYAGFVPT
                     EIDAKGCMRKIDLIFEKED"
     gene            complement(5192..>5779)
                     /locus_tag="JAM15_18315"
     CDS             complement(5192..>5779)
                     /locus_tag="JAM15_18315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAT6800199.1"
                     /translation="KKIFSGQYNTLSVSSGIALTAAVLSIVIKEWMYWYTRSAAKHTN
                     SDELMADAWHHRSDALSSVGSLIGILGARLGYAILDPIASIVICGCILKAALDIFKES
                     INKMVDHSCDNATETKIREVVLQQQGVDGIDELKTRMFGAKMYVDIEILADGNLALYD
                     AHRIAEGVHQTIENNFPQCKHCMVHVNTNELPYSP"
BASE COUNT         1791 a          978 c          996 g         2014 t
ORIGIN      
        1 ggggatagcc tgtggagaat tagtaagaca tattttagta tgcaaaattc tatgaagcag
       61 gaatcctgtg actttagtca tgggaggttc agaactatga attaacaaaa caattatgtt
      121 ctattggact aatatttata atgttttttg gagggtttgg aacaaactgg aatatggcta
      181 aacctgttgc tataccttct atattaatgt cttcactggg tgtaataatt acggctgggg
      241 ttacaggtat gttttgccac atggtaatag gaactagttt acttgaaggt ttattaattg
      301 gggcaattgc agcttcaaca gatgctgcat ctgtgtttgc tgtgttgcgt tctcaaaaac
      361 taaacttaaa gggttcactt gcatcattat tagaagttga aagtggaagt aatgacccaa
      421 tagcgtatat gttgacacta attcttttga cattgatgaa taattctggg gtagaactta
      481 ttgcaccaat ggtaataaaa caaatagctt ttgggttagc tataggattt atactagcaa
      541 aattatctgt ttatatttta agacattcaa acttcgagat agaaggattt tatactatat
      601 ttataacagc tattgcaata ctttcttatg catttagcga gtatcttgga ggaaatggat
      661 atttaagtgt ttacatttca ggtattatta taggaaatag taggatacct cttaaaaaaa
      721 gtttggttca tttctttgat ggaatttcat ggattatgca aataatgtta ttctttatgt
      781 taggattgtt atctttccct tctaagttac caaatgtatt tggtatagca atggccatat
      841 ctatattcat gatagttatt gcaagaccat tagcaacatt tatagttcta gcaaaattta
      901 aattctcaaa taaagaaaaa ttattcatat cgtgggtagg tcttagaggt gcggcttcag
      961 tagtttttgc aatttatgct gttactcaag gagtagccat agagaatgac atattccata
     1021 taatattttt tatagcgttg ctttcagtag gaatacaagg ttcattgata ccaactgtag
     1081 ccagaaagtt ggatttagtt gatgataata cacctgtatt aaaaacattt aatgattatg
     1141 atggggaaat tagctctaaa cttatcgaag taaatgttga tgagggtaat aaatgggcta
     1201 ataagagtat aatagattct aatataccag acgatatatt aatagttatg ataaaaagaa
     1261 aggaacaggt tttaatacct aaaggttcaa ccattataaa aacaggggat attttggtat
     1321 tgagtggaga tagaattgaa gaattaatac aattataatt tattttgcat tgactttaac
     1381 ctaaggggaa agtttaaact taaattaatc aaatctaatg cgcaggtgat gagatgtttt
     1441 ctataggaat gttttctaaa ataaataaaa taactacaaa gacattaagg tattatgaag
     1501 atatagggtt gttaaaacca gaatatgtag atgaatttac aaaatatagg tattatacaa
     1561 cagagcaatt acctaaatta catcagataa taactttaaa acaaatgggt ttatcattag
     1621 ctgagataaa aaaagctgta gaaaatcctg aagaagttga aaatatttta atgaataaag
     1681 aaaaagaaat gttggatgta attaaaagtg aagaatataa aataattaaa ctacgtaatt
     1741 accttatgaa tttgaaagga gaagtcaata tgaatgatgt aattattaag tctttaccaa
     1801 aagttaaagt tgcttctatg agaaaagtgt taaagggata tgatgaactt tttaatctat
     1861 ttccaaatgt aatggctgaa gaaatgatga aaacagagtg tacatgtgca gttcctgatt
     1921 attgttttaa tatatatcat gatggtgaat atagagagac tgatatggat gttgaaatgt
     1981 gtcaagctac aaatgattta aaggaagata cggatatatt aaaatttaaa gaattagatg
     2041 cagttgaaaa tgcagtttgt atattacaca atggtccata ttcaacatta ggaaaaactt
     2101 acgcagatgc atttaaatgg atagaggaca ataaatataa ggtggttgga aatcctagag
     2161 aatcttatat agatggtata tggaataaag agagtgaaga agactggttg acagaagttc
     2221 agataccagt gaaacgcata ttataatatg tctacaaagt ataaataaga ataaaaaagg
     2281 tggtgtctca aagtaaactt tttagtttat gagacactct ttttcatatg aaatcaagta
     2341 tatttttata attccgatta tgaaaaaagg cttatctcta tttttggaca gcctcttatt
     2401 tttttattat aaaaacttac taaatttctg attatctttt cataagttgg taaatgccga
     2461 tatatcccgt attttcgggc tgtatgggca ttttcttttt ggaagatacc ttgcataagc
     2521 tggcatttac cagcatgaaa atgcaaccaa aagtagtaaa taagtagtaa gatacatttt
     2581 cgatattaag aagccagcct ttctaactct gcctttgcag actggaaagt accgtgagca
     2641 taatacccta atgtcatggt tatgtttgcg tgtcccatga tgtattgcag ggtgtttggg
     2701 ttcattccct tatttgccat gttcgtacag taagtatgtc tgaatgaatg gggcgtgatg
     2761 tttggtaact tgtccttatg ggtcttgttg tacttcttaa tcaacccacg caccatactt
     2821 tcataatttc ctgctacctt tggcaatccc tcacggttca agaataagaa attgctataa
     2881 ccaccaacaa caagcggttg tgcttttcct cggttcttta aaattcgctt gagtgcttga
     2941 tatgctcttt ctgttaatgg aagctctcgc ttaccgtttt ttgtcttagc tttggaaata
     3001 tagtagccca cctctgtatc acgcaatagc tggtggtcta tgttaatcac acggttaagc
     3061 atatcaatgt gtgttgtcag tccgcataat tcagagatac gaagtcccgt ttccagcaga
     3121 agaataactt catcacgata cttgctgtaa acattatctg tttccataaa ggcaaggagt
     3181 ttttcttcct gctctggtgt taggataacc tttgcttccg tatcatcttc cagaacatca
     3241 ctcaacttgg aattaaaagg attttttctg atacagtcgt cttgtatcgc catatagaat
     3301 gaagccttta gggaacgctt atagttatct atcgtcttgt aagaataacc tttgccattc
     3361 attctgatag cccattcttt agcgtcggac tgcttgaccg tatcaatcgc cctcataccc
     3421 aatgggtcac tttccagtgc gttcacaaga tactgtcgtc ctaattccgt gtttctcttg
     3481 atgttctttc tttgattgtt ctttttttcg taaagctggc agactgtcat tttaccgccc
     3541 accgtgtcga taccgtcgtc aaggtctttt tttatctgct tttctttttc cctcaacgat
     3601 atatcatcac gttttccagc aggtgtcttg tctgtgggta caagcttcca agaatataca
     3661 aactgtggct tcccgaatat atcggtatat ttataaacgt atcttccgtc ttttctctgg
     3721 ctctctccaa gacgcaaatt gcgtccttta ctgtcttgtc ttttcattta gtatctcttt
     3781 catagtttct agtgcacggt gtctgtgttt gaacacagcc cctctggtat aattcataat
     3841 atctgcaatc tctgtatcac tcatttccaa gaagtaatac atcaatacat tgttacgttt
     3901 ttttcgggta gctgtttgag agcttctgca agttcatcat caaggacttt aatatctatg
     3961 ccacacacat taaaaattgt gtagtttgtt tcgtagtcgt cccatgttgc cagactttct
     4021 accgtaatgt ctggtaattc gctaaaagat atttccttgt tttttcttcg tcttaattct
     4081 ttgcggtagt tccagataat acctttgaca acttttttca gcttacattc aaactgacac
     4141 tgaattgttt tttggaagtc agacggtttc ataatctcac ctcctttcca gctatgaatt
     4201 gaaaagtgtt tatccctctt tccgcaccat atctgtacag caaggtgtga tttgcttcca
     4261 aaaaaatgaa aataattaaa aaaacttttc gggtattaaa aaagcccgca caaaatataa
     4321 attttgtacg agctactggt atagcgtatt taattgtaaa tagtatgctg ttaaattggg
     4381 cttgaatata ctgaattgta tttaaagcgt ttcatacggc aagccccctt tacaacattt
     4441 aaaccttaac ctttgtcttt ttggtaatcg tataaatata ttcctctggt gttggccgct
     4501 tatttccaaa gtatcgttta aaatttgcct gcacgtctgg gtctgtactt tccatagttt
     4561 tgtctatggt atcttgtagc atagccctaa attcagatac agaaacacct tgagctttag
     4621 caccaacttt cataatataa ttcatatctc gtcttttaag tcctatcatt agaaccaact
     4681 ccctaaaata agttaatctt ctttttcaaa aattaaatct atctttcgca tacagccttt
     4741 tgcgtcaatt tctgtgggta caaaccctgc gtagtgatac cccgtttttg cataactgtc
     4801 aataatttct ttgtgtttat cagtacaaag gaatacaact cctttcgcat tatagttaat
     4861 ttctacatac tcatattttt tcattcttca aaactccttt caaatacaaa tttatctttg
     4921 gatttattga cttttacaaa ctgggattta tcgttcaaat ttcataggta tatatctcat
     4981 accatcggat aattgctctt aatacatctt gtcatcctcg ctattttttg aacgattgtt
     5041 agaatttctc ctttggttat acttcttcat aattacaatt ttaagtaagc caacgacaat
     5101 caaaaccata acaatgataa tccaccagta ttgttccata acctacttcc cctcctttcc
     5161 ctttcaatag tcttaaatca tcttccctgt cctatggaga atagggaagt tcattcgtat
     5221 taacatgtac catacaatgt ttacattgtg gaaagttgtt ttcaatcgtt tgatggactc
     5281 cctcagcaat tctatgagcg tcataaagag ctaaattacc atcagctaat atttcaatat
     5341 ctacatacat tttcgctcca aacatgcggg tttttaattc atcaatacca tcaacccctt
     5401 gctgctgaag cacaacttcc ctaatctttg tttcagtagc attgtcacaa ctatggtcta
     5461 ccattttgtt aatgctttct ttgaaaatgt ccaaagcagc ttttaagata caaccgcaaa
     5521 tcacaatgct tgcaataggg tcgagaatag catagcctaa acgtgctcct aaaatgccaa
     5581 ttaaggaacc aaccgacgag agtgcatcag agcggtgatg ccatgcgtca gccataagtt
     5641 cgtcagaatt tgtatgcttt gcagcacttc ttgtatacca gtacatccac tcttttataa
     5701 caatggataa gactgccgcc gtaagtgcga ttccactaga gacagaaagc gtattgtact
     5761 gtcctgaaaa gattttctt
//
LOCUS       DACTZW010000144         5699 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.147, whole genome shotgun sequence.
ACCESSION   DACTZW010000144 DACTZW010000000
VERSION     DACTZW010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5699)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5699)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5699
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.147"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            93..962
                     /locus_tag="JAM15_18320"
     CDS             93..962
                     /locus_tag="JAM15_18320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800200.1"
                     /translation="MVIIKAIELYKKLDLEFNIKNINDDWSFMNFENDFITPEFRKKY
                     IGLVLDNAQNINKVYTTTFPDKEIIKQVIDKDEKDILIFSHHAMGYIASDEGFPFHDI
                     PLSYMEEMKNRRISFYVLHSPLDNYSDYSTSVSFAKAMGLEIVKPFCKYDDKIEVGVI
                     CKTSLKSIEEIKELIKKSVGHDVKLYDYGDSVLKDGLVAIAAGGGSYPFVAREVAELG
                     INLYITGFTKPLKHFEPVLEFHQIAKDNLINVIGATHYSTEKFACMGMVDYFKNLGLE
                     SEFLQGKYYLEDL"
     gene            1868..2575
                     /locus_tag="JAM15_18325"
     CDS             1868..2575
                     /locus_tag="JAM15_18325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAT6800201.1"
                     /translation="MIFTKSNKYDKDFLMKNMMGPNCIKILEELTSKIKLEKGMRILD
                     LGCGKGISSIFLAKEFDATVFATDLWIEPTENYKRFKEFKLDDKIFPIQAEAHELPYA
                     EGFFDAVISIDSYHYFGNKEGFLDNHISPLVKEGGILAMAMPGLKEDFVDCIPDELIP
                     FWQDNMNFHSITWWNKLWSESESVIVEKCEALNCHDEAWKDWINCDNSYAINDKKMME
                     VENGKYFNTISLIARTK"
     gene            3187..3687
                     /locus_tag="JAM15_18330"
     CDS             3187..3687
                     /locus_tag="JAM15_18330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAT6800202.1"
                     /translation="MIEGIKFIKAEEKYIYSYWQTFDKIAKERKYLAMDEAFPFEETV
                     EFIKNTINKNLPQLFIIDLESDNCIGWCDVLPKTEKVGYLGMGILKEYREKGIGSSLL
                     KQIIDLSKEYGYEKIELDVFKSNSRAIHVYKSLGFVEVNTISSGFTWNDRPVKEEVIQ
                     MELTLI"
     gene            complement(3937..4716)
                     /locus_tag="JAM15_18335"
     CDS             complement(3937..4716)
                     /locus_tag="JAM15_18335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800203.1"
                     /translation="MNKNILNNSFPEVPESFHNSLNKTLNSLPEREENYKMINNKTHK
                     LPFRKGLVATLAITLILSTTALAVGHIYSLVGKSSIKATYTSIPTTEQVKKDFNFTPN
                     IVSEFSNGYKFKGAYTVNKKALDKENNVLGKSKALSFEYKNGNDEISLDTANNVLGKS
                     SDNLKVVDTYKDINISYEAFAQKFVPEGYKMTEQDKIDEKSGKYTFGVGPNNESDKVE
                     VNEFKFLTWKQDGVYYSFTVQDSNLSMNDLVKMAHEVIDAK"
     gene            complement(4713..5192)
                     /locus_tag="JAM15_18340"
     CDS             complement(4713..5192)
                     /locus_tag="JAM15_18340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAT6800204.1"
                     /translation="MDKTTFTNNILESEQTLYRVSKSILGNDQDCEDAVNNAILKAYE
                     KLDSLKEEQYFKTWLIRIVINECNSLRRKRLKSLSFEDVFKNKKIDEKDDYSDLYTAI
                     QSLPKKIKIPIVLYYIEGYSVDEVKEILDIPQGTVKSRLSRGRTLLKTKLENTEVII"
BASE COUNT         2170 a          578 c          842 g         2109 t
ORIGIN      
        1 ttttaatttg aagtaggaat acttaaacgt ataaagttta ttatcggaaa tttctatatt
       61 aatatgtagt aattcaatat tattataaag gagtggttat tattaaggca attgaacttt
      121 ataaaaaatt agatttagaa tttaatatta aaaatattaa tgatgattgg agttttatga
      181 attttgaaaa tgattttatc actccagaat ttagaaaaaa gtacatagga ttagtattag
      241 ataatgctca aaatattaat aaagtataca caactacttt tcctgataaa gaaataatta
      301 agcaagttat agataaagat gaaaaagata ttttaatttt ttcacatcac gcaatgggat
      361 acatagcatc agatgaaggt tttccatttc acgacatacc actatcttat atggaagaga
      421 tgaaaaatcg tagaatttct ttttatgtat tacattctcc actagacaac tatagtgact
      481 attcaacttc tgttagtttt gcaaaagcta tgggtttaga aatagtcaaa ccattttgta
      541 aatatgacga taaaattgag gtaggagtta tatgtaaaac atcactaaaa tcaatagaag
      601 agattaagga attaattaaa aaatctgttg gtcatgatgt gaaattgtat gattatggag
      661 attctgtatt aaaagatggt ttagttgcta ttgcagcagg gggaggaagt tatccatttg
      721 tagcaagaga agttgctgaa cttggtataa atctatatat tactgggttt actaagcctt
      781 taaaacattt tgaaccagta ttagagttcc atcaaatagc aaaagataat ttaattaatg
      841 ttataggtgc tactcattat tctacagaaa aatttgcgtg tatgggcatg gttgattatt
      901 ttaaaaatct aggtttagaa tcagagtttt tgcaaggaaa atattactta gaggatttat
      961 aggacatatt aaacaataaa aataaacagt tagtaaaaat ttattttact aactgtttat
     1021 ttttttacct atttatccag tgttttgaaa aaatctatct ttatttttta aactaagaaa
     1081 atagactttt aattgttgat tagaagattt agttttgatg tcttttaaat tatttttcga
     1141 tattttttag tttatttttt gatgtatttt agattattat ttaggattga ttagaattta
     1201 taaatattta ttttagatta ttgtaaatat ttatttaaaa aaaatagaat tattatattt
     1261 atgataataa atggtataat aaaaggtaaa gtgtcaaata tgcactaaat taaataagtt
     1321 aattagtata taggttaaag tggaagtaat taaaacttat taagtattag aaaatgactt
     1381 cttattagag taagtatcta aaatgatata aaaattatga ttactcatta aagtgactat
     1441 tatagagtag ataaaattgc ccataaaaat agctataata gagtggataa gattactcat
     1501 taaagcgatt actgtagagt agataaaatt actcactaaa ataactataa tagagtggat
     1561 aagattactc attaaagcga ttactgtgga gtagataaaa ttactcacta aaataactat
     1621 aatagagtag ataagatact tattaaggtg attattgtag agtagataaa attacccatc
     1681 aaagttaatt atcacatatt agataagatt attcattaaa gttactatca tagagtggat
     1741 aaaattacac attaaaattg tctgttaaag aatgaataaa aaagagattg ctcaatataa
     1801 gaagcatata aaaaatcaaa catataaaat ttaataaata ataactgata gggaaaggaa
     1861 agatagaatg atatttacaa aaagcaataa atacgataag gactttctca tgaaaaatat
     1921 gatgggacct aattgtataa aaatattgga agaattaaca agtaagataa aactagaaaa
     1981 gggaatgcgt attttagact taggttgtgg taagggtata tcttcgatat ttttagcaaa
     2041 ggaatttgat gctactgtat ttgcaacaga tttatggata gaaccaactg aaaactataa
     2101 aagatttaaa gagtttaaat tggatgataa aatatttcca atacaggcag aggcacatga
     2161 actaccttat gcagaaggtt tctttgatgc agtgataagt atcgattctt atcactattt
     2221 tggaaacaaa gaaggatttt tagacaatca tatatcacct cttgtaaaag aggggggaat
     2281 acttgctatg gcaatgcctg gattaaaaga agatttcgtg gattgtatac cagatgaact
     2341 cattccattt tggcaagata atatgaactt ccattcaatt acatggtgga ataaactttg
     2401 gtctgaatcg gagtctgtga ttgtagaaaa atgtgaagct ttaaattgtc atgatgaagc
     2461 ttggaaggat tggataaatt gtgataattc atatgctata aatgacaaaa aaatgatgga
     2521 agtagagaat ggaaagtatt ttaatacaat ttctttgata gcgagaacta aataattgtg
     2581 atgaatttat aaaagtataa gataagtaga aatataagtt gaatgagagt ataagaagca
     2641 tagaaatata agttgaatta aagtagaagg taaataaaaa tgtaagttaa ataaagagtt
     2701 tatacaaaaa tgatttttta gattatttat acccaatcga gttgcttagg tcagttgggt
     2761 atttttattt ttttaaagtt aaattgcaaa tattattgtg tgatatatat tttaatacta
     2821 aatgtttgtt ttataagaaa taaactaata gaaaaaatag ttttaacaat gaaagcaaaa
     2881 aaggtattga tgaagattaa aaattttata gtaccatttt atatattttt ttatatattt
     2941 tattatactt taaatcaaat tttaaaatga ttaagtatat atacccaaaa gattaaagaa
     3001 ctatatttat tatactatta aaaattattt taatagagat acaagagata gatatattgg
     3061 ttttaatttt atagaaatat acaaagatat tttaagctaa tatatagtaa tttatatagc
     3121 attataaact agaatcatat aaaataagtt aactacaatc acaaattaaa aaggggaaat
     3181 gttaagttga tagaaggaat aaaatttata aaggcagaag aaaagtatat ttattcgtat
     3241 tggcaaactt ttgataaaat agcaaaagag aggaaatatc tagctatgga tgaagccttt
     3301 ccttttgaag aaacagttga atttataaaa aatactataa ataaaaactt accacaactg
     3361 tttataattg atttagaatc agataactgt attggttggt gtgacgtttt acctaaaact
     3421 gaaaaagttg gttatttagg catgggtatt cttaaggagt atagggaaaa aggtatcgga
     3481 agtagtcttt taaaacaaat tattgattta tcaaaagaat atgggtatga aaaaattgag
     3541 cttgatgtat ttaaaagtaa tagtagagct attcatgttt ataaatcttt agggtttgta
     3601 gaggtaaata caatatctag tggttttaca tggaatgata gacctgtaaa agaagaagta
     3661 attcaaatgg agcttacact tatataaaat aaagttaaag tctttaaaat tccatataca
     3721 cttgtataaa ataaagttaa agcccttaaa attccatata aaagaaatat ttttaagggc
     3781 tttttaataa tggttctttt gaaggtagct aaatatctaa aattttatat attaaattta
     3841 aagaaaatat aaagatggaa gatacaacca tgtttactaa taaaaaaatt aaagtcataa
     3901 ataataaact cataaacaac ttattattac ttatgtttat tttgcatcta ttacttcatg
     3961 agccatttta actaagtcat tcatagataa atttgagtct tgaactgtaa aagaatagta
     4021 aactccatct tgtttccatg tcaaaaactt aaattcatta acttcaactt tgtctgattc
     4081 attatttggc cctacaccaa atgtgtattt gcctgatttt tcatcaattt tatcctgttc
     4141 tgtcatttta taaccttctg gtacaaactt ttgtgcgaat gcttcataag aaatattaat
     4201 atctttgtaa gtatctacaa cttttagatt gtcagaactc ttcccaagta cattatttgc
     4261 tgtgtcaaga gatatttcat cattgccatt tttatattca aaactaagtg cttttgattt
     4321 tcctaaaaca ttattttctt tgtcaagtgc ttttttattt acagtatatg ctcctttaaa
     4381 tttatatcca ttactaaatt cagaaactat attaggggta aagttaaagt ctttttttac
     4441 ttgttctgta gttgggatag atgtataggt agccttaata cttgattttc caactaaact
     4501 atatatatgt cctactgcaa gggctgttgt gctcaatatc aaagtaatgg ctaaagttgc
     4561 aactaaacct tttctaaatg gtaatttgtg tgttttatta ttaatcattt tataattttc
     4621 ctctctttct ggtaaactat ttagtgtttt gtttaaacta ttatgaaaac tttctggaac
     4681 ttctggaaac gaattattta atatattttt attcatatga ttacctccgt gttttctaat
     4741 ttagttttta ataatgttct tcctcttgat aatctacttt ttacagttcc ttgaggtata
     4801 tctaatattt ccttaacttc atctactgaa taaccttcaa tatagtaaag gactattgga
     4861 attttaattt ttttaggtag actttgaata gcagtataca aatcgctata gtcatctttt
     4921 tcatcaattt ttttgttttt gaagacatct tcaaatgata gagattttaa tcgtttgcgt
     4981 cttaatgaat tacattcatt tatgactatt ctaatcagcc atgttttaaa gtattgttct
     5041 tccttaagag aatccaactt ttcatatgct tttaaaatag cattgttgac ggcatcttca
     5101 cagtcttggt cgtttcctag aatagactta gatactcgat acaaagtctg ttctgattca
     5161 agtatattgt ttgtaaatgt agttttatcc aactgagttc cttcccttct atgcaaatcg
     5221 tagcgctact tttttgcctt tcacttatta gataaaattt tactatagat ggttcacttt
     5281 ttttatgatt atttgataaa tttaagtttg aaagttttgc ctattctata caaatattct
     5341 ataatatatt tttttctagt attttcccct catatataaa gccatgtaga tatattaaac
     5401 tttagaagcc atttatatat ttagttttat agtaagtgtt tatattaagt aattataaaa
     5461 tagtaagtat ttgatgttga gtagttagaa aataatgctt ttggattatt tacttcatgt
     5521 atagatttaa aataagtttt ttaattaatg actaaagata acggtatttt gactaaaagt
     5581 aggcttttaa gaaaaaacaa tgaaacttaa atgagaatca agagttagaa atgtcattat
     5641 tttagataga gatgaacata aataaactta aaaaatataa attataaaaa taataattt
//
LOCUS       DACTZW010000145         5664 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.148, whole genome shotgun sequence.
ACCESSION   DACTZW010000145 DACTZW010000000
VERSION     DACTZW010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5664
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.148"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(115..1857)
                     /locus_tag="JAM15_18345"
     CDS             complement(115..1857)
                     /locus_tag="JAM15_18345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HAT6800205.1"
                     /translation="MVKSKKKIFVFLILIAVFIIFASYIRNYTNDTKKDSVRGTIPFE
                     KMEYKRPNIQSICENINKCNDKLLTAKTAKEQLNLFNEVDKIYQDFYSTLTIAKIRNN
                     IDSSDEFYSKEYKYLMSKSVDVDMSYKDFQDRFVTSKFSKELEKELGKDTFNYLKNIG
                     KLNSKEVEGLLKKEQDLVVKYEDLLAKSTVSIDGIEVDFEEALSRPNLSPEEYVKIYS
                     DYLKKYNPIFGDIFLELIQTRTEIASKQGFKNYIDYAYMNLNKDYSQEEAKKFRQDVK
                     DYIVPLYREISSKPSDSSIYIKVYKNRSFRKFDKVLEDISPKLKESFDYMKKYDLYDY
                     SSGKNKSPGGYTTYINKYKAPFLFNTWDNSFLGVTSFAHEFGHFYNYYNSINLNNKMQ
                     PSIDVCEVHSTSLEILFYKYFDDFFGKQSEAIKKEHLSIVLNTIIDACLYDEFQEIIY
                     KNPYMSLNDINKLFFDLEEEYGVSNNILREKNAPFWILVSHNFQVPFYYLSYGLASDV
                     SLQIWQLSQEDYRKAVDVYMDFLNQNTDAGFKDVVEKVNLQLPFQDGNLEEISSTLYD
                     YFGIDNPLELKNAS"
     gene            2286..3662
                     /locus_tag="JAM15_18350"
     CDS             2286..3662
                     /locus_tag="JAM15_18350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HAT6800206.1"
                     /translation="MKTIVRRLILYADGMRPTQIMVSGFAAIIVIGALLLTLPIASQS
                     GESIGLLNALFTATSAVCVTGLVMVDTATYWSLFGQIVIITLIQIGGLGFMTVATMFS
                     LMARKKIQLRERLLIQESLNQADLSGLVRLTRFVLIITITIEGIGALVLSTVFIPQFG
                     LSKGIWYSVFHAISAFCNAGFDLMGSVSGPFTSLNSYVNNFTVSMTVCALIVLGGLGF
                     PVVLDIVRKRRFSKLNVHSKVVLFSTATLIFVGALFIFLIEFNQKATMADLPLKGKVL
                     SAIFQSVTARTAGFNTLDLATLRESSVFVMIILMFIGASPASTGGGIKTTTLAVLIIT
                     VRSFLSGKSDIEAFERRLAPSTIKKSLGIFVISISAVIFGTLIISITQPNFTLVQSAF
                     EVTSALATVGSSLAGTPNLNALGKIIIIIFMFMGRVGSLTLFMAILSGGRRKSQPIRY
                     AEGKIMVG"
     gene            3973..4644
                     /locus_tag="JAM15_18355"
     CDS             3973..4644
                     /locus_tag="JAM15_18355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HAT6800207.1"
                     /translation="MKQYIVIGCGRFGSSVASTMHLLGHQVMAIDKNEDSVQSISDKV
                     THSLIVDVTDEQALRSLGLGNFDVAVVAIGSDIRASIMATLIAKEMGVELIICKAKDE
                     LQAKVLYKIGADRVVFPERDMGVRVAHNLVSDNILDHIELDPEYSIVEIVTPNSWVGK
                     TLIELELRARYEITVLAIKTGKNINVTPSPDEELTAGSILVIIGQNTSITAITSGNKG
                     IIRRR"
     gene            4835..5632
                     /locus_tag="JAM15_18360"
     CDS             4835..5632
                     /locus_tag="JAM15_18360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HAT6800208.1"
                     /translation="MITNINSKDNEKLKYTRALLKSKNRNKESKFIIEGYRIVMLALE
                     CMANLDYVFINEEFENKKEHVKLLEDLDKKNTKIYKTTNKNFKELVDTENTQGIIGVV
                     SFKKKKLSESINKKDKFVLILDRIQDPGNMGTIIRTADSAGVDAIIALKGCVDIYNPK
                     VIRSTMGSIFDMNIIDASQDETVDMLKSLDFNIVSSYLNTENFYDKIDYGSKVALVIG
                     NEANGINEELVSKSDILVKIPIYGKAESLNAAISSAILMYEIKKYLI"
BASE COUNT         2102 a          679 c          916 g         1967 t
ORIGIN      
        1 caagagtctt aaagatttct gatacaattt tattaaacat taattgtgtg tgaaaaaata
       61 tcacttattt caatctaata ctaaatctta agagtgagta taaagtatta gaaattaaga
      121 agcatttttt agttcaagtg gattatctat accaaaataa tcatataaag tagagcttat
      181 ttcctctaaa tttccatctt ggaaaggtaa ttgtaaattt accttttcta ccacatcttt
      241 aaatccagca tcagtatttt gatttaaaaa atccatatat acatcaacag cttttctgta
      301 atcttcttgt gataattgcc atatctgaag tgatacatca gatgcaagac cataactcaa
      361 gtaataaaaa ggaacttgga agttatgaga tacaagtatc caaaaaggag catttttttc
      421 tctaagtata ttattggaaa ctccatattc ttcctctaaa tcaaaaaaca atttattgat
      481 atcatttaga ctcatatatg gattcttgta tataatttct tgaaattcat cataaagaca
      541 agcatcaata atagtattta aaacaatcga taagtgttct ttttttatag cttcagattg
      601 tttaccaaaa aaatcatcaa aatatttata aaatagaatt tctaaagatg ttgaatgaac
      661 ttcacataca tctatacttg gttgcatctt attatttaag ttaatactgt tgtagtaatt
      721 ataaaaatga ccaaactcat gagcaaaact agtaacacct aaaaaagaat tgtcccatgt
      781 attaaacaag aaaggtgctt tatatttatt tatataagta gtatatcctc caggcgattt
      841 gttttttcca gaagaataat cgtacaagtc atattttttc atatagtcga agctctcttt
      901 tagttttgga gatatatctt caagtacttt atcaaacttc ctaaatgagc gatttttata
      961 tactttaata taaatagaag aatcagatgg tttagatgaa atctctctat ataatggaac
     1021 tatgtaatct tttacatctt gtctaaattt tttagcttct tcttgagaat agtctttgtt
     1081 taggttcata taggcataat ctatataatt cttaaatcct tgcttacttg ctatttcagt
     1141 tcttgtctgt ataagttcta agaatatgtc accaaatata ggattgtatt tttttaagta
     1201 atctgaataa attttcacat attcttcagg gctaagattt ggtcttgaca aggcttcttc
     1261 aaagtctacc tctataccat ctattgatac tgtagattta gctaataagt cttcatattt
     1321 tacaactagg tcttgctctt ttttaagcaa accttcaact tctttagaat taagttttcc
     1381 aatgttcttt agataattaa atgtatcctt tccaagttct ttttctaatt ctttagagaa
     1441 tttagaagtt acaaatctat cttgaaagtc tttgtatgac atgtcaacat ctactgattt
     1501 actcataaga tacttatatt ccttagagta aaattcgtct gatgaatcta tgttatttct
     1561 aatttttgct atagtaagtg tactgtaaaa atcctgataa attttatcaa cttcattaaa
     1621 taaatttaat tgttccttag ctgttttagc tgttaaaagt ttgtcgttac acttgttaat
     1681 gttttcgcaa attgactgta tattaggacg cttatattcc attttttcaa aaggaatagt
     1741 tcctctaaca gaatcttttt ttgtatcatt agtataattt cttatgtatg atgcaaatat
     1801 aataaaaact gcaattaaaa ttagaaaaac aaatattttc ttcttggatt taaccataaa
     1861 aatcctccaa tcatggatat agttattaat tattttacta tattaaatat aaaaaatgca
     1921 tgttaagaaa atttaacata aagatataga taagattata aataatataa aaaatttaac
     1981 ttcaaaaaag tatatgaaat ttatactggt aaaatgataa ataaatttta agtacaaaat
     2041 agtaaaagct atgatagttt tagatctatt atatgtaaaa aatatagacg tttttggtgc
     2101 aatttaaatt aaaagatata tataaaaatt taaaatattc caaacagaaa ttataaaaat
     2161 tactatcatt gtctttatgc aatatttata ctataataga ataataattt agaggaaagc
     2221 tctaaaaata aacaaattaa gggtcttaac agtagtgatt ttatgttaag gaggtataaa
     2281 gaaagttgaa aacaatagtt agaagactta ttctctacgc agatggaatg cgtcctactc
     2341 aaataatggt atctgggttt gctgcgatta ttgtaatcgg agcattgttg ttaacactcc
     2401 cgatagcgtc gcagagtgga gagagtatag gcttattaaa tgctctattt acggctactt
     2461 cagcggtttg tgttactggt ctagttatgg tagatacagc aacttattgg agtttatttg
     2521 gacagatagt tataataaca ttgatacaaa ttggtggtct tggatttatg accgtagcca
     2581 caatgttttc acttatggca cgaaaaaaaa tacaactaag agaaagatta ttaatacaag
     2641 agtcattaaa tcaagctgat ttatcaggac ttgtaagact tacaagattt gtattaataa
     2701 taaccataac aatagaggga ataggtgcac tggttttatc aactgtcttt attccacaat
     2761 ttggtttgtc taaagggata tggtatagtg tatttcacgc aatatcagcg ttttgtaatg
     2821 ccggatttga cttgatgggc agtgtaagtg gcccatttac atcgttaaat tcttatgtaa
     2881 acaactttac agtatcaatg actgtttgcg cacttatagt gcttggaggg ctaggattcc
     2941 ctgttgtact tgatattgta agaaaaagaa gattttcaaa attaaatgtg cattctaagg
     3001 ttgtattgtt ttcaactgct acacttattt ttgtgggtgc attatttatt tttcttatag
     3061 aatttaatca aaaagctact atggcggact tgcctttaaa gggaaaagta ctatcagcaa
     3121 tatttcaatc agtaacagca agaactgctg gttttaatac gcttgattta gctactttac
     3181 gagaaagtag tgtatttgta atgataattt tgatgtttat tggagcatca cctgcatcaa
     3241 ctggtggggg tataaaaaca acaacactag ctgttttaat cattacagtt agaagttttc
     3301 tatcaggaaa atcagatata gaagcttttg aaagaagatt agctccatca actataaaaa
     3361 aatctcttgg tatatttgta atcagtatat cagcagttat ttttggaaca ttgattattt
     3421 caataactca gcctaatttt acattagttc aatcagcttt tgaggttaca tcagcacttg
     3481 ctacagttgg ttcaagttta gctggaactc caaacttaaa tgctttaggt aagattataa
     3541 taataatctt tatgtttatg ggtagagttg gttctcttac tttatttatg gctatacttt
     3601 ctggtggtag aagaaagagt caaccaatca gatatgcaga aggtaaaatt atggttggtt
     3661 aagttaccaa ggagtaatat aaatttataa tggatttaga gtagcactgt aaatctgttg
     3721 ataaaataaa tgagcctaga tgtaattata tgaagaaata aaatcgacta atgaacaaaa
     3781 ttaattaatg aaataaaaaa acagggaaat aaaatacaaa taaaaaggta aatcaaaatt
     3841 aaattaatct gtgtatataa aattatatat tgtgtataag ttttgtatgt gtaaagtata
     3901 taagttttgt atgtgtaaac aattaattta agagatatta tataaattgt gtattaggga
     3961 ggaagtttcg agatgaagca atatatagtc attgggtgtg ggagatttgg aagttcagtt
     4021 gcgtctacta tgcatctttt aggacatcaa gtaatggcaa tagacaaaaa tgaagattca
     4081 gttcaaagta tatctgacaa ggtaacccat tcacttatag tggatgttac tgatgagcaa
     4141 gcgttaaggt cattaggttt aggtaacttt gatgtagcag tagttgcaat aggttctgat
     4201 ataagggcat ctataatggc gactcttata gccaaagaaa tgggtgtaga gttgataata
     4261 tgtaaggcaa aggatgaatt acaagctaaa gttctttata aaattggcgc agatagagtt
     4321 gtatttccag aaagagatat gggagtaaga gttgcacaca atttagtttc ggataatata
     4381 ttagaccata ttgaacttga cccagagtat tcaattgttg aaatcgtaac tccaaatagt
     4441 tgggttggca agacacttat agagcttgaa ttaagagcta gatatgagat aactgtactt
     4501 gctataaaaa caggtaaaaa tataaatgtt acaccttctc cagatgagga acttacagcc
     4561 ggaagtatcc tagttataat cggtcaaaat actagtataa cagcgataac atctggaaat
     4621 aaggggataa ttagaagaag ataatttact atttaatata tatttaattg caatgaaagt
     4681 aaagagtatc atataattat gaatagttat atgatactat ttttatttaa tcgaaggtag
     4741 tatttatttg taagattaga taaagagaag ttaaattaaa agtaaggagg ctgtgctaat
     4801 ataaaaattt ataagttatt agcatttaga taaaatgatt acaaatataa acagtaagga
     4861 taatgaaaag ttaaagtata caagagcact attaaaatca aagaatagga ataaagagtc
     4921 aaagttcata atagaaggat acagaatagt aatgcttgca cttgaatgta tggcaaacct
     4981 tgattatgta tttatcaatg aagaatttga aaataagaaa gaacatgtaa aactattaga
     5041 agatttggat aaaaaaaaca caaagatata caagactact aataaaaact ttaaagaatt
     5101 agtggataca gaaaatactc aaggaataat aggtgtagtt tcatttaaga aaaaaaaatt
     5161 aagtgaaagt ataaataaaa aagataaatt tgtattgatt ttagatagaa tacaagaccc
     5221 aggaaatatg gggactataa taaggactgc tgattctgct ggagtagatg ccataatagc
     5281 actaaaggga tgtgtcgata tatacaaccc aaaagtaatt aggtctacta tgggttctat
     5341 ttttgatatg aatataattg atgcttcaca agatgaaact gtggacatgc ttaaatcatt
     5401 ggattttaat atagtttcaa gttacttaaa tacagaaaat ttttatgaca aaatagatta
     5461 tggttcaaaa gtagcattgg tgataggaaa cgaagcaaat ggaataaatg aagaacttgt
     5521 atcaaagtct gatattttgg ttaagatacc tatatatggt aaagccgagt cgttaaatgc
     5581 tgcgataagc tctgctatac tgatgtatga aataaaaaaa tacttaattt aatgtattgt
     5641 aataaatata atgtcatgtt ataa
//
LOCUS       DACTZW010000146         5360 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.149, whole genome shotgun sequence.
ACCESSION   DACTZW010000146 DACTZW010000000
VERSION     DACTZW010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5360
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.149"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(197..1396)
                     /locus_tag="JAM15_18365"
     CDS             complement(197..1396)
                     /locus_tag="JAM15_18365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013361172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAT6800209.1"
                     /translation="MLSKRLNFITPSYTIGISSKVKEMESNGVKVINLSIGEPDFNVP
                     NNAKSYGIDSLNKDYTKYDLVPGLKILREEICKKLIEENNCNYSIDEIVVSSGAKNSI
                     TNTLLALTDEGDEVLLPKPYWVSYPEMIKLVNAVPVFIDTKKENGFKLTKEELEKSIT
                     DKTKILVINNPSNPTGSVYTKDELIEIVDVCIQNKIYILADEIYEKICYTGEFTSIAS
                     LSEEAKDITITINGFSKSAAMTGLRLGYTASNKTIAKAMSSIQGHLISHPSLTAQYIA
                     YGALKDCSIDIDNMVKTYKSRRDLIKSKLDSIDNVGYVNPNGAFYIFIDLSKVSEKFE
                     YKDSFSIEFCNQFLEEYNVAVVPGIAFGMDKYIRISYACSENTFLSGLDKLKEFVYKI
                     MHNNLDE"
     gene            1769..4120
                     /locus_tag="JAM15_18370"
     CDS             1769..4120
                     /locus_tag="JAM15_18370"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside triphosphate reductase"
                     /protein_id="HAT6800210.1"
                     /translation="MVEFVKKRDGRVIPFNEDRITRAIFLAATNVAEREGIVPDYKLS
                     EQLTQEVIKFLNHKYSESVPSVEDIQDSVVKVLIETGHAKTSEEYIIYRTERSRIRNS
                     KTRLMKAIEEITFEDAEDADIKRENANINGNTAMGTMLQYGSTVSKEFCKTHILKPEH
                     SFAHDNGDIHIHDMDFLNMGTLTCCQIDVKKLFNGGFSTGHGFLREPQDIISYGALAA
                     IAIQSNQNDQHGGQSIPFFDYGLAEGVYKTFKKFYIGNLAKALKLFKGIENNDVIKNI
                     VYNTEKETNQKVGLKRDELYLNLEKEKLIQTFDIDDELVNKMQNFAFEESYRETDKKT
                     YQSMEAFIHNLNTMHSRAGAQVPFSSVNFGTDTSEEGRMVTKNLLLSQERGLGNGETP
                     IFPILIFKVKEGINLNPEDPNYDLFKLSCRVSAKRLFPNFSFLDAPFNAKYYKKGEPD
                     TEATYMGCRTRVLSNVCGSETVSGRGNISFTTVNLPRLGIKHGIINNEKANLDGFFEE
                     LDEKINLIIEQLLERLEVQGNKKMKNFPFLMGQGVWKGSDDLGPEDTLKEVIKQGTLT
                     IGFIGLAECLIALIGKHHGESKEAQELGLKIVSHMRHKMDEATDKYKLNFSLMGTPAE
                     GLSGRFTKIDKKVYGEIKGITDKEYYTNSFHVPVYYNISAYDKIEIEAPYHELTNAGH
                     ITYVELDGDPSDNLEAFETVIKAMKDLGIGYGSINHPVDRDPICGFSGVITSNICPVC
                     GRNEDESDIKFERIRRITGYLVGTVDRFNNAKKAEVKDRVKHR"
     gene            4142..4681
                     /gene="nrdG"
                     /locus_tag="JAM15_18375"
     CDS             4142..4681
                     /gene="nrdG"
                     /locus_tag="JAM15_18375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HAT6800211.1"
                     /translation="MKIRMSSTISYDSIVDGPGLRMVIWTQGCIHNCKECHNPQTHDL
                     CGGFYMDTEEIINKIKSLKLQKGITLSGGEPFLQPEPLEEIAREAKINGLDVWSYTGF
                     TFEQLLDKKNRAYFKNLNLLKQIDILVDGKFIAEKKDISLKFRGSSNQRIIDVQKSLK
                     YKQVFLVEQYMKDDLSIAE"
BASE COUNT         2094 a          597 c          854 g         1815 t
ORIGIN      
        1 atttttttgt tataataaat ttagaattta acttatatag tttaatttga taatttgatg
       61 aaaaaaataa aagacttact gatttttaaa tctataggtc ttttattttt tatctaacat
      121 ttaaattaag ttgttgaata tatcttatat tacttaccat atatattaat taccattaat
      181 acattatatc taattactat tcatctaaat tattatgcat tattttatat acaaattctt
      241 ttaatttatc taatccagat aagaaagtat tttcactgca agcataggat atacgaatat
      301 atttatccat accaaatgct atgccaggaa caactgcaac attatattct tctaaaaatt
      361 gattacaaaa ttctatagaa aaactatctt tatattcaaa tttctcagat actttagaaa
      421 gatctataaa tatatagaat gcgccatttg gattcacata tcctacatta tcaatagagt
      481 ctagttttga tttaattaaa tctcttcttg atttatatgt tttaaccata ttgtctatgt
      541 caattgagca atctttcaag gctccatagg ctatgtattg tgctgttaga cttgggtgag
      601 atataagatg tccttgtata gaactcattg ctttagcaat cgttttatta gatgcagtat
      661 atcctaatct taatccagtc attgcagctg acttagaaaa accatttata gttattgtta
      721 tatctttagc ttcttcgctt aatgatgcaa ttgatgtaaa ttcaccagtg tagcatattt
      781 tttcatatat ttcatctgct aaaatatata ttttattttg tatgcataca tctactattt
      841 ctattaattc atcttttgta taaacactac cagtaggatt tgaaggattg tttattacaa
      901 gaatttttgt tttatctgtt atagattttt caagttcttc ttttgttaac ttaaatccat
      961 tttctttttt agtatcaata aaaactggaa cagcattaac taacttaatc atttcaggat
     1021 aactaaccca ataaggcttt ggcaataaga cttcatctcc ttcgtctgtt aaagctagta
     1081 aagtatttgt tattgagttt tttgctccac ttgatacaac tatttcgtct attgaatagt
     1141 tacagttatt ttcttcaata agttttttac agatttcctc tctaagtatt tttaatcctg
     1201 gaactaaatc gtatttagtg taatctttat ttaaagaatc aataccataa gattttgcgt
     1261 tattaggtac attaaaatcg ggttctccta tactaagatt tattacttta actccattac
     1321 tttccatttc tttaacttta gaactaatac ctattgtgta ggatggtgtt ataaagttta
     1381 gtctttttga taacataaaa tgcctccttt taaattatta tttatattat acgacaaatt
     1441 taaagaattt acataaggaa atttgtagat atatacatta atatatataa tagcctacac
     1501 tttttgccta aaattagtgt aaaaaaaaga gaaaaaaatt ttaactttca aagttgttag
     1561 aaacgctact gttcaaaata tccacatagt atttgcaatg atttgcgcaa gtttgactat
     1621 tatgtacaaa tttggtaatc ttaatatagc aattattaag ataatccctt taacttagtt
     1681 gaaggggatt tttttagact taacatacta catatagtgg tatggggatt aataaaatac
     1741 aatatatagt aacaggaggt ttttttaatt ggttgaattc gtaaaaaaaa gagatggaag
     1801 agtaattcca tttaatgaag atagaataac aagagctata tttttagcag caacgaatgt
     1861 tgcagaaaga gaaggaatag tacctgatta taaattatct gagcaattaa ctcaagaagt
     1921 aataaagttt ttaaatcata aatactcaga atcagttcca agtgttgaag atatacaaga
     1981 ttctgtagtt aaggttctta tagaaactgg ccatgcaaaa actagtgaag aatatataat
     2041 atacagaact gaaagaagta gaataagaaa ttcaaaaaca agattgatga aggcaataga
     2101 ggaaattacc tttgaagatg cagaagatgc tgatataaaa agagaaaatg caaatattaa
     2161 tggtaataca gcaatgggaa ctatgttaca atatggaagc actgtatcta aagaattttg
     2221 taaaacacat atattaaaac cagagcattc ttttgctcat gataatggag atatacacat
     2281 acatgatatg gattttttaa atatgggaac attaacttgt tgtcaaatag atgttaaaaa
     2341 actattcaat ggtggatttt caacaggaca tggcttttta agagagccac aagatataat
     2401 aagttatggt gcattagctg caattgctat acaaagcaat caaaacgatc aacatggagg
     2461 tcaaagtata ccatttttcg attatggatt ggctgaaggt gtatataaga catttaagaa
     2521 attctacata ggaaatttag ctaaagcatt gaagttattt aaaggaattg aaaataatga
     2581 tgtgataaag aacatagtat ataatacaga gaaagaaaca aatcaaaaag ttggtcttaa
     2641 gagagatgaa ttgtatctaa acttagagaa agagaaatta atacagactt ttgatataga
     2701 tgatgaactt gtaaataaga tgcaaaactt tgcatttgaa gaatcgtata gagaaactga
     2761 taaaaaaaca tatcaatcta tggaagcatt tatacacaat ctaaatacaa tgcactctag
     2821 agcaggtgca caggtaccat tttcaagtgt aaacttcgga acagatactt ctgaagaagg
     2881 aagaatggta actaagaatc ttctattatc tcaagaaaga ggtttaggta atggagagac
     2941 accaattttt ccaattttaa tatttaaggt caaagaaggc ataaatttaa atcctgaaga
     3001 ccctaattat gatttattta aattatcatg cagagtatca gctaaaagac tattccctaa
     3061 ttttagtttt ttagatgcgc cttttaatgc aaaatattat aaaaaaggtg aaccagatac
     3121 agaggctaca tatatgggtt gtagaacaag agtacttagt aatgtgtgtg gttcagaaac
     3181 agttagtggt agaggaaaca tatcttttac tacagtaaat ttaccaagat tgggtataaa
     3241 acatggtatt ataaacaatg aaaaggctaa tttagatggt ttctttgaag aattagatga
     3301 gaagataaac ttaattatag aacaattatt ggagcgcctt gaggttcaag gaaataaaaa
     3361 gatgaagaat tttccattct taatggggca aggtgtatgg aaaggttctg atgatttagg
     3421 accagaagat acactaaaag aagtaataaa acaaggaaca ttgacaattg gatttatagg
     3481 tttagcagag tgtcttattg ctcttatagg taaacatcat ggagaaagta aagaagctca
     3541 agaattagga ttaaaaatag tgtcacatat gagacataaa atggatgaag caacggacaa
     3601 atataaatta aatttctcct taatgggtac tccagcagaa ggtctttcag gtaggtttac
     3661 taaaatagat aaaaaagttt atggagaaat taaaggtatc acagataaag aatattatac
     3721 taattcattc catgtaccag tttattacaa tataagtgca tatgataaaa ttgagataga
     3781 agctccatac catgaattga ctaatgcagg tcatataaca tatgtagagt tagatggaga
     3841 tccatctgat aatttagaag cttttgaaac tgttataaaa gctatgaaag atttgggtat
     3901 aggatatgga agtataaatc atcctgtaga tagagaccca atatgcggtt tttcaggtgt
     3961 aataacaagt aatatatgtc ctgtatgtgg aagaaatgaa gatgaaagtg acatcaagtt
     4021 cgaaagaata agaagaataa caggatactt agttggtaca gttgatagat ttaataatgc
     4081 taaaaaagca gaagtaaaag atagagtaaa acatagatag ttttatttgg gggaataagt
     4141 tatgaaaata agaatgtcat ctactataag ttatgacagc atagttgatg gaccaggatt
     4201 aagaatggta atatggactc aaggatgtat tcataattgt aaagagtgcc ataatcctca
     4261 gacacatgat ttatgtggag gattttatat ggatacagaa gaaattataa ataaaatcaa
     4321 atcattgaaa ttacaaaaag gcattacgct atcaggagga gaaccatttt tacaaccaga
     4381 accattagaa gaaatagcaa gagaagctaa aataaatggg ttagatgtat ggtcatatac
     4441 tggatttacg tttgaacaac tgttagataa aaaaaataga gcgtatttta aaaatttaaa
     4501 tttactaaag caaattgata ttttagtgga tggaaaattt atagctgaaa aaaaagatat
     4561 aagcttaaag tttagagggt catcaaatca aaggataatt gatgttcaaa aaagtttgaa
     4621 atataaacaa gtgtttttgg ttgagcaata tatgaaggat gatttatcta tagcagaata
     4681 aaatataaat aaacaggatt aaatatatgc atatatttaa tcctgtttat tttcatataa
     4741 tatttcaagc ttgtataatg taacaattaa accaaaagac tcattgtata tttgaaatta
     4801 agttttttat agtttatagg tgttttatgt ggattacgaa tgatatagta ttgatacatt
     4861 atttaataga ttcttatgcc aagaaacaat taatttatag aaattcttaa ttgttacaat
     4921 ataaatatct agataagtta taagatactg ataaataatt tataaagttt attaatctaa
     4981 tattgtgtgt gaatattaag tggtcaagta gtctaaaaaa tgaaaaagat ttaaaaaagt
     5041 gttctaacta aacacataag tgttaaattc atgtataagt ataggttaga tacataagaa
     5101 ataattatgt aatatctatc tttgtaaaaa aatattaaat tttgtaattt gtggataaat
     5161 atgtttataa tgtggataat atttaatgta ataagttaaa gcaatatgaa tcaactgttt
     5221 ataatgtgga taatattata aatgtatgaa taattgcagt atttaaaaac aaaaaaagtt
     5281 aaaaaagttg ttgactctaa aagaaaaagt tggtatagta atacttgtcc tcaagaaaag
     5341 ggcaaacaaa taaagcataa
//
LOCUS       DACTZW010000147         5318 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.150, whole genome shotgun sequence.
ACCESSION   DACTZW010000147 DACTZW010000000
VERSION     DACTZW010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5318
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.150"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            100..1590
                     /locus_tag="JAM15_18380"
     CDS             100..1590
                     /locus_tag="JAM15_18380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008427168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HAT6800212.1"
                     /translation="MFQFETQIHKLRHDVLTAIARLGKEDNLTREAMDNIQYEIIKGE
                     KPTYRCCVYKERAIISERVNVSMGLQPGQDKIDLDTMDIEEDEQIIYILEAACDSCPI
                     NEFTVTDICRGCLAHRCKEACKFGAITHVGGMAYINHELCKACGMCKKACQYDAISEV
                     VRPCKSVCPTNALGFDRENMKAMIHEDKCLNCGACMSACPFGAISDKSLIAPVARKLV
                     QKEKMYAVVAPAITGQVEANVTYGQIKNAIKSLGFVDVLEAACGADAVTVHESLEFAE
                     RMEKGEAFMTNSCCPGFVGYIEKTYPNHVGKISSTVSPMIASGRFIKSHEPDAKVVFI
                     GPCTAKKSEAAKKELKGAVDYVLTFEEIMALFEAFDIDLAKCSNEDIDDASIFGRGFG
                     AAGGLTKAIENYLAEKGIGVNFEPVKISGSREIKKTMTMANLGKLEGNFIEGMMCEGG
                     CINGSGKFLSGAKVKATFDRKNSQSTKKSVLANTKIKDFSNINLEK"
     gene            1848..3344
                     /locus_tag="JAM15_18385"
     CDS             1848..3344
                     /locus_tag="JAM15_18385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008427168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HAT6800213.1"
                     /translation="MFEFETQLKRLKHEVLTAVARLSIEENLTKENIEKIPYEIIKGE
                     KARYRCCVYKEREVVLERAQLALSLTPNSKYGDINPDSVSLDTDEQIIYIVEAACDRC
                     PINEFTVTELCRGCLAHRCKEACKFGAISYINGRAYINHDLCKACGMCKSSCQYDAIS
                     EVVRPCKSVCPTGALDFNRNTMKAMIHEDNCINCGACMSACPFGAISDKSLIAPVAKK
                     LAKKENMYAIVAPAITGQIDSNITYGQLKNAIKSLGFVDMIEASCGADAVTVHESNEL
                     IERIKSGDNYMTNSCCPGFFKYIEKMFPDEKDRISSTVSPMVATGRLVKKIDSDAKVV
                     FIGPCTAKKSEATEKSLKDSVDYVLTFEELMALFEAFNIDLSKCSNEDINDGSIFGRG
                     FGASGGLAKSVQNYIAEKGLSFDFEPIKVSGPRQIKKTMTMAKLGRLEGNFIEGMMCE
                     EGCINGAGKFLSGVKAKNTFDRKNGQSTKKSVLSNDKIKEFEDVNLER"
     gene            3478..4404
                     /locus_tag="JAM15_18390"
     CDS             3478..4404
                     /locus_tag="JAM15_18390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAT6800214.1"
                     /translation="MKKIVLKDILFLVTTLSIIVILLLVTNITTNSKIKSTSESYLKS
                     DKNSVRQNGIQRSTKSSTKNTAFKTTILNTGKSDCILVEIGNKVIMIDTGEDKNGKQI
                     VDRLKEKGINTLDYLILTHLDKDHIGGVDSVLSSVKVKNIIQANYKKDSKQYDEYIDS
                     LKKADIEPVLLKDNMNIVINSAEINIHPASKSKYESSNDYSIITNISYGAHKFLFAGD
                     AEEERLSEFINGNTLKYDFVKMPHHGRYDKLTETFLESTSPQYAVITCSEKKEPEEGV
                     LKILERLNIKTFLTSNGEVAINSDGKTLSVNQ"
     gene            4523..4714
                     /locus_tag="JAM15_18395"
     CDS             4523..4714
                     /locus_tag="JAM15_18395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800215.1"
                     /translation="MLDRFFGEGGFGGCAWWIIILFFLFLAFQDCWVEMDLCAWIPFL
                     ILLLILCECGDVFDGGCGC"
     gene            4937..5287
                     /locus_tag="JAM15_18400"
     CDS             4937..5287
                     /locus_tag="JAM15_18400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800216.1"
                     /translation="MAIVDKIFNEIKLMVARLLLGKKYSEYEEKDLVYNTEEEVILIT
                     LKRLVFQGNVNEAEEILFDKAKTVTSENMQYIAIEFYTMLMEKTDEELEAMNFSKQEV
                     YQGIEDIRKVLNLE"
BASE COUNT         2102 a          536 c         1026 g         1654 t
ORIGIN      
        1 ataaaattta aacatataat attttatgta tatattaata aaaggacata ttgtgttata
       61 atggtatcgt ataaaatcat ttacgggggt ggtattaaaa tgtttcaatt tgaaacacaa
      121 atacacaaat taagacatga tgttttaact gcaatagcta gacttggaaa agaagataac
      181 cttaccagag aagcaatgga taatattcag tatgaaataa taaaaggtga gaaacctaca
      241 tacagatgtt gtgtttataa agaaagagct ataatatctg agagagtaaa tgtaagtatg
      301 gggttacaac caggtcaaga taagatagat ttagatacaa tggatataga agaagatgaa
      361 caaattatat atattttgga agctgcatgt gacagttgtc caataaatga atttacagta
      421 acagatattt gtagaggatg tctagcacat agatgtaaag aagcttgtaa atttggagct
      481 ataacacatg tcggaggaat ggcctatata aatcatgaat tatgtaaggc ttgtggaatg
      541 tgtaaaaaag cttgtcaata tgatgccatc tcagaggttg ttagaccatg taagagtgtt
      601 tgtccaacta atgccttagg atttgataga gaaaatatga aagctatgat acatgaggat
      661 aaatgtttaa actgtggagc atgtatgtca gcatgtccat ttggagcaat atctgataag
      721 agtttgatag ctcctgtagc tagaaagttg gttcaaaaag agaaaatgta tgcggtagta
      781 gctccagcta taacaggtca agttgaagca aatgttacat atggtcaaat aaaaaatgct
      841 ataaaatcac taggatttgt tgatgtatta gaagcagctt gtggagcaga tgcagttaca
      901 gttcatgaaa gcttagaatt tgctgaaaga atggaaaagg gagaggcttt tatgacaaat
      961 tcttgttgtc caggatttgt tggttatata gaaaaaacat acccaaatca tgtaggaaaa
     1021 atatcttcta cagtgtctcc tatgatagct agtggtagat ttataaaaag tcatgaacca
     1081 gatgctaaag ttgtattcat aggaccatgt acagccaaaa agagtgaggc agctaagaaa
     1141 gaattaaaag gagctgttga ttatgtactt acttttgaag aaataatggc attatttgag
     1201 gcatttgata tagacttggc taagtgttca aatgaagata tagatgatgc atcaattttt
     1261 ggaagaggtt ttggagctgc tggtggtctt acaaaagcta tagaaaatta tcttgctgaa
     1321 aaaggtattg gtgttaattt tgaacctgta aagatttctg gttcaagaga aatcaagaaa
     1381 actatgacta tggctaattt aggaaagcta gaaggtaatt ttatagaagg aatgatgtgt
     1441 gaaggtggtt gtataaatgg ttctggtaaa ttcttatcag gtgcaaaggt caaagccact
     1501 tttgatagaa aaaattctca atcaactaag aaaagtgtct tagcaaatac aaagataaaa
     1561 gattttagta atataaattt agaaaaataa agataataca aagtaacaaa aatacatatt
     1621 gttaatagag ttgttctaag ttgaggttta acttttggac aactctattt ttatttatat
     1681 atttaattaa tgaacaacta aaataaaaat tacatatata atattttgta tataacttaa
     1741 caaagtatat gcctatgtta taataattta tagaaataaa taaaaaatac aatatacata
     1801 atagtagaaa tatagtaaaa aggtgtgatt tatagggagg attacttatg tttgaatttg
     1861 aaacgcaact aaaaaggttg aaacatgaag ttttaacagc agtagcaaga ctatctattg
     1921 aagaaaattt aacaaaagaa aatatagaaa aaattccata tgaaataatt aaaggagaaa
     1981 aggcgagata tagatgttgt gtttataaag agagagaagt agttcttgaa agggcgcaac
     2041 ttgcattaag tttaactcca aatagtaaat atggagatat aaatccagat tcagttagtt
     2101 tggacacaga tgagcaaatt atatatatag ttgaagcagc atgtgataga tgtccaataa
     2161 atgaatttac agttacagag ctttgtagag ggtgtttggc tcatagatgt aaggaagcat
     2221 gtaaatttgg ggcaatttct tatataaatg ggagagcata tataaatcat gatttatgta
     2281 aggcttgtgg aatgtgcaaa agttcatgtc aatatgatgc tatatcagaa gttgtaagac
     2341 cttgtaaaag cgtttgtcca acaggagctt tggattttaa tagaaacact atgaaagcaa
     2401 tgatacatga agataattgt ataaattgtg gagcatgtat gtcagcatgt ccttttggag
     2461 caatatctga taagagtttg atagcacctg ttgcaaaaaa acttgcaaag aaagaaaata
     2521 tgtatgcaat agtagctcca gctataacag gtcaaataga tagtaatatt acatatggtc
     2581 agttaaaaaa tgctataaaa tcacttggat ttgtagatat gatagaagct tcttgtggag
     2641 cagatgcagt tacagttcat gaaagcaatg agcttattga aagaataaaa tcaggagata
     2701 attacatgac aaattcatgt tgtccgggat tttttaagta tatagagaag atgttcccag
     2761 atgaaaaaga tagaatatca tctacagtgt ctcctatggt agcaacagga agattagtaa
     2821 aaaaaataga ttctgatgct aaagttgtat ttatagggcc atgtacagct aaaaagagtg
     2881 aggcaacaga gaaaagttta aaagattcag tagattatgt acttactttt gaagaactaa
     2941 tggcattatt tgaagcattt aatatagatt tatcaaaatg ttcaaatgaa gatataaatg
     3001 atggttcgat ttttggaagg ggatttggag cgtctggtgg acttgccaaa tcagtacaga
     3061 actatattgc tgaaaaggga cttagttttg attttgaacc tataaaagta tctggtccaa
     3121 gacaaattaa aaagacaatg acaatggcta aattgggaag attagaaggt aattttatag
     3181 aaggaatgat gtgtgaagaa ggttgtatta atggagcagg taagttttta tcaggtgtaa
     3241 aagctaaaaa tacttttgat agaaaaaatg gacaatctac taaaaagagt gttttatcta
     3301 atgataagat taaagaattt gaagatgtaa atttagaaag ataattgttt tggtacagtc
     3361 atttttttat catgccacaa atatgcctaa aatttgccct ttttatatgt gtattttaca
     3421 gagttaaggt tgctatacta taaatatgta ataaataaaa tttataggag cttttggatg
     3481 aagaaaatag tattaaaaga tatcctgttt ttagttacta cattatctat aatagtaata
     3541 ttattgcttg taacaaatat aactactaat agtaagataa aatcaacaag tgaatcttat
     3601 ttaaaaagtg acaaaaatag tgtgaggcaa aatggtatcc agaggagcac aaagagtagc
     3661 acaaaaaata ctgcatttaa gactactata ctaaacactg gaaagtctga ttgcatattg
     3721 gttgaaatag gtaacaaagt cataatgatt gatacaggag aagataaaaa tggaaaacaa
     3781 atagtggata ggttaaaaga aaaaggaata aatacacttg actatttgat tttaacccat
     3841 ttagataagg accatatagg tggagtagat agtgtgttat ctagtgttaa agtaaagaac
     3901 attatacaag caaattataa gaaagatagt aagcaatatg atgaatatat tgactcactt
     3961 aaaaaagctg atatagaacc agtgctacta aaagataata tgaatattgt aatcaatagt
     4021 gcagaaataa acatacatcc ggcttcaaaa agcaagtacg agagttcaaa tgattattca
     4081 ataatcacta atataagcta tggagcacat aagtttttat ttgcaggaga tgcagaggaa
     4141 gaaagattgt cagagtttat aaatggaaat actttaaaat atgattttgt taaaatgcct
     4201 catcatggaa gatatgacaa attaactgaa acatttttag agtctacttc accccaatat
     4261 gctgttatta catgttcaga gaaaaaagaa ccagaggaag gtgttttaaa aatattggaa
     4321 agattgaata taaaaacatt tttgacttct aatggagagg tagctatcaa tagtgatggt
     4381 aagacattga gtgtgaatca ataatttttt taaaaatatc taaaaaaaat ttaaaaaaat
     4441 cattagcaaa tattacccct taaacatagt atattttagg agctgaaact ccacatacaa
     4501 aatgactagg aggtaacata ttatgttgga tagatttttt ggtgaaggcg gatttggtgg
     4561 atgtgcttgg tggataataa tattattctt cttattctta gcattccaag attgttgggt
     4621 tgaaatggac ttatgtgcat ggataccttt cttaatatta ttattaatac tttgtgaatg
     4681 tggtgacgtt tttgatggag gatgtggatg ctaaaaaaat caatttagat gatttaataa
     4741 agcttatggt gggtataaat aaaataccaa accaatcaca atctagtgtt tgaaggtagt
     4801 cggaaatccc ccgctacctt ctttttttta ttgttaaaat ttatttttga attatttcat
     4861 ttacatataa taatttttac gataaagtct gatataatta aaaagaaaat aaaatttatt
     4921 tataggagat gtaaaaatgg ctatagtgga taagattttc aatgagataa aacttatggt
     4981 tgcaagactt ttattgggaa aaaaatacag tgaatatgaa gaaaaagatt tagtgtataa
     5041 tacagaagaa gaagttatac ttataacttt aaaaagatta gtttttcagg gaaatgtaaa
     5101 cgaagcagaa gaaattttat ttgataaagc taagactgta actagtgaaa atatgcagta
     5161 tatagcaata gaattttata ctatgcttat ggaaaagact gatgaagaat tagaagctat
     5221 gaatttttct aaacaagaag tttatcaagg tatagaagat attagaaaag tattgaattt
     5281 agaataaaag atatatgaaa atattgaaat aaattaat
//
LOCUS       DACTZW010000148         5215 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.151, whole genome shotgun sequence.
ACCESSION   DACTZW010000148 DACTZW010000000
VERSION     DACTZW010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5215
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.151"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(78..803)
                     /locus_tag="JAM15_18405"
     CDS             complement(78..803)
                     /locus_tag="JAM15_18405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HAT6800217.1"
                     /translation="MKTISKQELEKTLEKHYLWLKNNNAGEKADLKELRLENMDLRGY
                     CLSNIDFSWSDLINLNLEKADLENSIFNNSYLSDCSLKNSILKNADLSGANFRFCDLS
                     NSDIRGANLENSNLEHATLNGVISDESTRFFKLYCPETGAFIGYKKCFNFRMVQLLIP
                     SDAKRVSATSNACRCDKAKVLSITSIDGKESFKSARAYADENFIYRVGETIVAEDFNE
                     NRWKESTTGIHFFLTREEAIGYL"
     gene            1281..3380
                     /gene="nrdE"
                     /locus_tag="JAM15_18410"
     CDS             1281..3380
                     /gene="nrdE"
                     /locus_tag="JAM15_18410"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HAT6800218.1"
                     /translation="MNWIELNNQVIIKNEQGKYQLEKDKEALSSYIEEFIQPKLRKFN
                     NLEERLKYLIDEGYYLKEVINQYSIDVIKNIYDMIDKHKFEFQSYMSANKFYQNYALK
                     SNDGKEILETYNDKVLIVALTLGNGDKDLALNLADKIVKQEFQPATPTFLNAGRKRAG
                     EMVSCFLLSVEDSTEGISYAISSSNHLSKIGGGVALNLSKLRASGESIKDIEGAAGGV
                     VGVAKMLEQSFSYFNQMGARQGSGAVYLTVFHPDFELLMDTKKINADEKIRLATLSLG
                     AIIPDKFMELAEKNEVAYAFYPHTVYKKYGVSLDEIEMDEWYDKLVNDSDIRKKEINP
                     RQMLTKIAQMQQESGYPYVVYIDTANREHTLKDVGIIKMSNLCCEIFQYQTPSEIEGY
                     GGKNEWGQDISCNLGSLNIANVMDNKTIESTVETAIRALSFVADSTDIKPVPTVSNSN
                     SKSHSIGLGAMNLHGYLVRENILYTSDDAIDFSNVFFAMVRYYSIKASMKIAIERNQT
                     FEGFDKSEYVKGRNSKVLSKYYEQSYLPKSEKVRALFEGIYIPTKEDWTKLLDEVKEK
                     GIYNAYLMAVAPTQSISYVQNATSSIMPITEPVEVRTYGDSTTIYPMPFLTNDNMLYY
                     QSAYRMDMRKVIDLVATVQNHVDQGISTTLFVTDEKTTRDIARHYIYAYKKGLKSLYY
                     TRTKMTRDTHECLVCSV"
     gene            3393..4364
                     /gene="nrdF"
                     /locus_tag="JAM15_18415"
     CDS             3393..4364
                     /gene="nrdF"
                     /locus_tag="JAM15_18415"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HAT6800219.1"
                     /translation="MTFNLHKIHNAVNWNREEDGFTQAFWEQNVKQFWLPEEISVSKD
                     IKVWNELSNKEKELYKKVLGGLTLLDTKQGNNGIPSMMSLTENLQRKAVLSFMGTMEE
                     IHAKSYSSIFMTLLSNLEIDELFEWIETEPTLQRKADLVLAQYENTTNQEGLYLSMVT
                     SVFLESFLFYSGFFYPLYLSGQGKMVASGEIISLILRDESLHGKYIGLLAQEIYDSFD
                     KMDKKMLEEKMYSILYSLMENEIEYTNVIYRESGLEKEVVNFLKYNANRALENLGFEK
                     LYTVDAINPIVLNGLSTETKTHDFFSTKGNGYQKGVYEELEDEDFII"
     gene            4440..5066
                     /locus_tag="JAM15_18420"
     CDS             4440..5066
                     /locus_tag="JAM15_18420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800220.1"
                     /translation="MKYEWRKRDKELYLPKKNPVIIEIPEQKFIMLKGSGDPNSKEFI
                     EAIGVLYSLAYAIKTMPKKGIVPEGYFDYTVFPLEGIWDKGEKSKGLDVLIKEDLIYT
                     IMIRQPDFVTQDLLDKATDIVKNKKPHNLLEKVRFGSINEGLCVQMLHIGSYDNEPES
                     FDIMNEFCKKNKLIRKSYTHREIYISDARKVSPESLKTVLRFEVEREV"
BASE COUNT         2040 a          600 c          874 g         1701 t
ORIGIN      
        1 atagattata atttttttga aattacaatc tatactcttt tgttattttg tttatatatt
       61 tataaaactt tagcatttta tagataacca atagcttcct ctctagttaa aaaaaagtga
      121 atccctgtag tcgattcttt ccatctattt tcattaaaat cttcagctac aatcgtttct
      181 cctactctat atataaaatt ttcatcagca tatgcacgag cacttttaaa agattcttta
      241 ccatctatac tagtaattga cagtactttt gccttatcac atctacaagc atttgatgta
      301 gcagacactc tttttgcgtc gctgggtatt aataattgta ccattctgaa attaaaacat
      361 tttttatagc ctataaatgc tcctgtttca ggacaataca atttaaaaaa acgggtactt
      421 tcatctgata ttactccatt taaagtagca tgttctaaat tggaattttc taaattagct
      481 cctctaatat ctgagttaga taagtcacaa aatctaaaat ttgcaccact taagtctgca
      541 ttttttaata tagaattttt taatgaacaa tccgaaagat aagaattatt aaaaatagag
      601 ttttctaaat ctgctttttc taaatttaaa ttgataaggt cagaccacga aaagtcaata
      661 ttacttaagc agtatcctct taagtccata ttttctaatc ttaattcttt taaatctgcc
      721 ttttctccag cattattgtt tttaagccat aaataatgtt tctcaagtgt tttttctaat
      781 tcttgtttag aaatagtttt cattaaaatc accttcataa atttattttt atatatgtag
      841 tagcaaaata gtcatatatt taattatata acaataaata aaaaacttct aaataatata
      901 taaaatatca tcttgaaagt acttttttca atatatcaga atatattttt aagctattta
      961 gagataattt aaatttttaa acaggacata ataagcttgt atttttttat atttgagttg
     1021 ataaaaattt ctttaaataa aaataatgtc aattataaag taataaaagt ttagatataa
     1081 aaaaatttgt gtatatacta tatgtagtat ataatagata aagcactgac tatatgtagt
     1141 gcttttgttt ttgaaaaata cttattgcat ttctataatt atagattaat tttgggattt
     1201 caactgataa gtaccaaaag aaataataag caaattaagt gaaattatgg cacaagatta
     1261 tgttaaaagg acggtaaata atgaattgga tagagcttaa caatcaagtg ataattaaaa
     1321 atgaacaagg taagtaccaa ttggaaaagg ataaggaagc cttaagtagt tacatagaag
     1381 aatttataca accaaagttg agaaaattta ataacctaga agaaagattg aagtatttaa
     1441 tagatgaagg ttattattta aaagaagtaa taaatcagta tagcatagat gttattaaaa
     1501 atatatatga tatgattgat aaacataagt ttgaatttca atcatatatg agtgcaaata
     1561 agttttatca aaattatgca ttaaagagca atgatggaaa ggaaatatta gaaacatata
     1621 atgataaagt gttaattgta gctttgacac taggaaatgg cgataaagat ttagctttaa
     1681 acttggcaga taaaatagta aaacaagaat ttcaaccagc tacacctact tttttaaatg
     1741 ctggaagaaa gagggctgga gaaatggtat catgtttttt actatctgta gaagatagta
     1801 cagaaggtat atcatatgct atatcttcat caaatcactt atcaaagatt ggtggaggag
     1861 ttgcactaaa tttatctaaa cttagagcat ctggcgaatc tatcaaagat atagaaggtg
     1921 cagctggagg tgttgttgga gtagctaaaa tgttagaaca atcatttagt tactttaatc
     1981 aaatgggagc tagacaaggt tctggtgcgg tgtaccttac tgtattccat cctgattttg
     2041 aattgttgat ggatactaaa aagataaatg cagatgaaaa aataagactt gctacattat
     2101 cattaggagc tataatacca gataaattta tggagttggc agaaaaaaat gaagtagcat
     2161 atgcatttta tcctcatact gtgtataaga aatatggagt ttctcttgat gagatagaaa
     2221 tggatgagtg gtatgataaa ttggttaatg atagtgatat aagaaaaaaa gaaataaatc
     2281 ctaggcagat gttgacaaaa atagcacaga tgcaacaaga aagtggatat ccatatgtag
     2341 tgtacataga tacagctaat agagaacata cattaaaaga tgttggaatt attaaaatgt
     2401 ctaacttatg ttgtgagata tttcaatatc aaacaccttc agaaatagag gggtatggag
     2461 gaaaaaatga atggggacaa gatataagtt gtaacctagg ttctttaaac atagccaatg
     2521 taatggataa taaaactata gaaagtacag ttgaaacagc aataagagca ctgtcatttg
     2581 tagcagatag cacagatata aaaccagtgc caacggtaag caatagtaac agcaagtctc
     2641 attctatagg attaggagct atgaatttac atggatactt agtaagagaa aatattttat
     2701 atacttcaga tgatgctata gatttttcta atgtattttt tgcaatggtt agatactatt
     2761 caattaaagc ttctatgaaa atagccatag aaagaaatca aacttttgaa ggatttgata
     2821 aatcagaata tgttaaggga agaaatagca aggttttatc aaaatactat gaacaatctt
     2881 atctacctaa gtcagaaaag gtaagagcat tatttgaagg gatttatata ccaacaaaag
     2941 aagattggac aaaattattg gatgaagtaa aagaaaaagg gatatataat gcatatttaa
     3001 tggcagtagc accaactcaa agcattagtt atgttcaaaa tgctacatca agtataatgc
     3061 caattactga gccagtagaa gtaagaacat atggagactc tactacaata tatccaatgc
     3121 catttttaac aaatgataat atgttgtatt atcaatcagc atacaggatg gatatgagaa
     3181 aggtcataga tttagtggca acagttcaaa accatgttga ccaaggtata tcaacaacac
     3241 tgtttgttac agatgaaaag acaactagag atatagctag acattacata tatgcctata
     3301 aaaaaggttt gaaaagttta tattacacaa gaacaaagat gacaagagat actcatgagt
     3361 gtctagtgtg ttcagtatag ggagagaaat atatgacatt taatttacat aaaatacata
     3421 atgcagttaa ctggaataga gaagaagatg gatttacaca agctttttgg gaacaaaatg
     3481 taaaacaatt ttggcttcct gaagaaatat ctgtttctaa agacataaag gtatggaatg
     3541 aactaagtaa taaagaaaag gaattatata aaaaagtatt gggtggttta acattactgg
     3601 atacaaaaca ggggaataat ggaataccat ctatgatgag tttaacagaa aacctacaaa
     3661 gaaaagctgt cttgtctttt atggggacta tggaagaaat acatgcaaaa agttattctt
     3721 ctatatttat gactctactt tctaatttag aaatagatga attatttgaa tggatagaaa
     3781 cagaaccaac attacaaaga aaggctgatt tagttttagc tcaatacgaa aatactacaa
     3841 atcaagaggg attataccta tcaatggtta caagtgtatt tttagagagt ttcttgtttt
     3901 attcaggatt cttttatcca ttgtatctat ctggtcaagg aaagatggta gctagtggag
     3961 aaataatatc gcttattctt agagatgagt ctttacatgg taagtatata ggattgctag
     4021 cacaagaaat atacgattca tttgataaaa tggataagaa gatgttagaa gagaagatgt
     4081 attctatact ttatagcctt atggagaatg agatagagta tacaaatgtt atatacagag
     4141 aaagtgggct tgaaaaagag gttgtgaact ttttaaaata caatgcgaat agagctttag
     4201 aaaatctagg gtttgagaag ctatatactg tagatgctat aaatccaatt gtattaaatg
     4261 gtcttagcac tgaaaccaaa acacatgatt tcttttcaac taagggtaat ggataccaaa
     4321 aaggagtgta tgaggaatta gaggatgaag attttataat ataatttata attatgacac
     4381 actgttgtca cttttagcgt gataatatca atgtataaaa tatatatgga ggtattttta
     4441 tgaaatatga atggagaaaa agagataaag agttatattt acctaaaaag aatcctgtaa
     4501 taattgaaat accagaacag aaatttatca tgttaaaagg gagtggagac ccaaattcta
     4561 aagaatttat tgaagcaata ggagtacttt attctttggc atatgcaata aaaaccatgc
     4621 ctaaaaaagg aattgtacca gaagggtatt ttgactatac ggtttttcct ttagaaggta
     4681 tatgggataa gggagaaaaa agtaaaggct tagatgtact tattaaagaa gatttaattt
     4741 acactataat gatacgtcag ccagattttg ttacacaaga cctgttggat aaagctactg
     4801 atatagtaaa gaataaaaaa cctcataatc ttcttgaaaa agttagattt gggtctatta
     4861 atgaagggct atgtgttcaa atgcttcata taggttcata tgataatgaa ccagaaagct
     4921 ttgacattat gaacgaattt tgcaaaaaaa ataaacttat aagaaaatct tacacacatc
     4981 gtgaaattta tataagtgat gctagaaaag tatcgcctga atcattgaag acggttttac
     5041 gttttgaagt agaaagggaa gtataaatat tttgaataat ttataagagt tataaaaagt
     5101 gaagtctgtt tagacttcat tttttgatgc aattttaaaa ttaaatttga tgtttcataa
     5161 tattttaaaa actttctact tttattagtg tgaataactg ttgctattaa ataat
//
LOCUS       DACTZW010000149         5200 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.152, whole genome shotgun sequence.
ACCESSION   DACTZW010000149 DACTZW010000000
VERSION     DACTZW010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5200)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5200)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5200
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.152"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            163..1056
                     /locus_tag="JAM15_18425"
     CDS             163..1056
                     /locus_tag="JAM15_18425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase"
                     /protein_id="HAT6800221.1"
                     /translation="MKNKKFIVIILIISILIGVLVKEYSSREIKKDDINVSKYIKYAD
                     LASKNNAQVNWKYVASIVAVLNKNNLKNVKDSQIQEVSDLFVKNFSKNNKINKLSDIL
                     DELEFSNRQKRLVDNYIDNLKDYGIKPERLKSDTKYMKFIAEIKTEAIQNYKDYKILP
                     SITIAQAIIESSWGKSTLAKQYNNLFGIKADAYWKGKSVTLETKEHLDTIIDDKFRIY
                     DDKNESIKDHAKFLATNKRYKNNGVFDAKTYIYQAKALEKAGYSTAKDENGNSIYAAR
                     LIELIQQYNLQLIDSEIQSEV"
     gene            1104..3404
                     /locus_tag="JAM15_18430"
     CDS             1104..3404
                     /locus_tag="JAM15_18430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800222.1"
                     /translation="MKKIFSIFISCMVVVTTITGCSSGEVIKNTSPINSVKNLDFSFE
                     VKPEIFEVSVESGGSKEKISEPSKERKVSNFKKNKTEASWTYPDENIDINIKKEDSYL
                     DVNIKSNLEKETSFNWPKVEGESYILPLYEGKFIPSNDKYWKEYLNESTYNVIESFSM
                     QFFAVNKAKYSVIYIIENEFNNVIEFSSKDKINFTFKHEYPSINKNKEYGFKIYLTNK
                     NITDVAKTYKNYIVDKGEFKTLKEKSKENKNIEKLYGAPHIYFGDKSIITINDIEWNK
                     LKENLSDDLTNWMKELLSMKSGNSEFIKVINQIKTQDYIDKYQKNQIVQAFNEVMQMN
                     TFYNEKVFESKDREIKKVLDKGISKLSRVELIEFNKKLLKSKLEESVNDVATWAKYNT
                     TDVINDINKSGIKNAWIGFDDMEEGYISLEMVKRANELGYLVGPYDSYHSIHKPGEEK
                     WSTASFKDKSLYENATIENKKGEKETGFQGEGRKLNPTLSLPSVKERVQSILDEGYEF
                     NSWFIDCDATGEIYDDYSQNHITTQTQDLNARLERMSYIRDHANMVIGSEGGNDFSSS
                     TIAFAHGIETPAFAWVDKDMSKNKGSEYYVGKYYSPTGGVPEIFSKQIPVKERYKKIF
                     IDPIYSLPLFRLVYNDSVISSHQWLWGTLKIKDEVGSRMMKEVLYNTPPMYYIDRTEW
                     EKHKDEIISNNKVWSAFNKKAIKKEMTDFKFISEDRLVQMTEYGEDLKVLVNFSQKDI
                     KYNDEVIKANSLVIYDADSKVIYKPE"
     gene            3638..4129
                     /locus_tag="JAM15_18435"
     CDS             3638..4129
                     /locus_tag="JAM15_18435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800223.1"
                     /translation="MYENNKVIYNFERCEKLENALYLSQFNTYKNFKLTSKKTVINSL
                     DTSTYNMNIHSISLVDTMECISSEDEQMTGKKLILVGDIDTDVTLDYVVNKRNRSFSK
                     KNILKLKIPFSTFIQMPRKIENKDKINLKYLIQDITSSILDDNLFISVTAIISYENSS
                     KIE"
     gene            4157..5104
                     /locus_tag="JAM15_18440"
     CDS             4157..5104
                     /locus_tag="JAM15_18440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800224.1"
                     /translation="MRITKTTFNDVFSNDANGSIIKVEKYVDKKCASVFEILTYTIIV
                     TNTSRYKTGNIFFKDYISKYIEFINNTVKVNGIIKRGLDPQQGFYIGRIDASCKKIIS
                     FKSVVLPNSAHRIIKNSANIYYYYKCNLDKFPTRISIESNRVYTNVNKIVFKQLNISN
                     TLKAPKNLRDILKVNVNSKIFDVKPMKNLINKGSNLKLCNSIVFGCIEVEIDYSCKNR
                     SNFKTVNKFNDIKKDKYYKNDIQNNNENINDCKKQISFGDNKVKKITKTFGFSCFICS
                     PVGIIYEDMKNINIKIEHTSINELNPEELFVNTSLLLYY"
BASE COUNT         2233 a          469 c          844 g         1654 t
ORIGIN      
        1 aactattttg tgtgatagaa aactatatat tataacaata gtagtgcctt taattaaata
       61 tatttcataa atcttcataa aatcttcaaa atttcgtaaa gaatatgtta caaaagtaag
      121 gtatattata ttcagcagat agtataaggg aggacaatat ttatgaagaa taaaaaattc
      181 attgttataa tactgataat atcaatttta ataggtgtat tagtgaagga atattcatct
      241 agagagataa aaaaggatga tataaatgtc agtaagtata taaaatatgc tgatttagca
      301 agtaaaaata atgcacaagt taactggaag tatgtagctt ccattgttgc tgtgttaaat
      361 aaaaataact taaaaaacgt taaggattca cagatacaag aagtatcaga tttatttgtt
      421 aagaattttt ctaaaaataa taaaataaat aagttaagtg atattttgga tgagttagaa
      481 tttagtaata gacaaaaaag attggttgat aattatatag acaatcttaa ggattatggt
      541 ataaaaccag aaagattgaa gtctgataca aaatatatga agtttattgc tgaaattaaa
      601 acagaagcaa tacaaaatta taaggattat aaaatacttc catctataac tattgcacaa
      661 gctataatag aatctagctg gggcaagtca actttggcaa aacaatataa caatctattt
      721 ggtataaagg ctgacgctta ttggaaaggt aagtcagtga ctttagaaac gaaagaacat
      781 ttagatacaa ttatagatga taaatttaga atatatgatg ataaaaatga atctataaaa
      841 gaccatgcaa aatttttagc cacaaataaa aggtataaaa acaatggtgt atttgatgca
      901 aaaacgtata tatatcaagc taaagcatta gaaaaggcag gttatagtac tgcgaaggat
      961 gaaaatggca atagtatata tgcagctcgt ctaatagaat taattcaaca gtataatctt
     1021 caattaatag acagcgaaat tcaaagtgaa gtgtaacttt tatgtaacat aggagtgata
     1081 tatttatcga ggaggtggct tttatgaaaa aaatattctc gatatttata agttgtatgg
     1141 ttgttgtaac tactattact ggatgtagta gtggtgaggt gataaaaaat acatcaccta
     1201 tcaatagtgt taaaaatttg gattttagtt ttgaggtgaa acctgaaata tttgaggtat
     1261 cagttgaatc tggtggttca aaagaaaaga tatctgaacc ctcaaaagaa aggaaagtat
     1321 caaattttaa aaagaataag acagaggcat cgtggacgta tcctgatgaa aatatagaca
     1381 taaatataaa aaaagaggac agctatttag atgtaaatat taaatctaat ttagaaaaag
     1441 aaactagttt taattggccc aaagttgaag gggaaagtta tatactacca ctttatgagg
     1501 gtaagtttat accaagtaat gataagtatt ggaaggagta tctaaatgag tcaacttata
     1561 atgttataga atctttttca atgcaattct ttgcagtaaa caaggcaaag tattctgtga
     1621 tttatattat cgaaaatgaa tttaacaatg taattgaatt tagttctaaa gacaagatta
     1681 attttacatt taaacatgaa tatccaagta tcaataaaaa taaggagtat gggtttaaaa
     1741 tatatttgac taataagaat attacagatg tagcaaaaac ttataaaaat tatatagttg
     1801 ataaaggaga atttaaaaca ttaaaagaaa aatctaagga aaataaaaat attgaaaaac
     1861 tttatggagc accacatatt tattttggag ataagtctat catcacaata aatgatattg
     1921 aatggaataa attaaaagaa aatttatcag atgatttgac taattggatg aaagagcttt
     1981 taagtatgaa gtctggcaat agtgaattta taaaagtaat taatcaaata aaaactcaag
     2041 attatataga taaatatcaa aaaaatcaaa tagtacaagc atttaatgaa gttatgcaga
     2101 tgaatacttt ttataatgaa aaagtttttg aaagcaaaga tagagaaata aaaaaagtat
     2161 tagataaagg tatatctaaa ttaagtaggg tagaacttat agagtttaat aagaaattat
     2221 tgaaatcaaa attggaagag agcgtgaatg atgttgctac atgggcaaaa tataatacaa
     2281 ctgatgtaat taatgatatt aataagtctg gtattaaaaa tgcgtggata ggatttgatg
     2341 atatggagga aggttatata tccttagaga tggttaaaag agctaatgag ttaggttatc
     2401 tcgtagggcc atatgattca taccactcta tacacaaacc aggggaagaa aagtggagta
     2461 cagcatcatt taaagataaa tctctatatg aaaatgctac catagaaaat aaaaaaggtg
     2521 aaaaagaaac tggatttcaa ggagaaggaa gaaaactaaa tcctacattg tctttaccaa
     2581 gtgtaaaaga gagagtacaa agtatattgg atgaaggata tgaatttaat tcttggttta
     2641 tagattgtga tgctacagga gaaatctatg atgattattc tcaaaatcat ataacaacac
     2701 aaacacaaga tttaaatgct agacttgaaa gaatgtcata tataagagac catgcaaata
     2761 tggtcatagg ttcagaaggt ggaaatgatt tttcaagtag tactatagca tttgcacatg
     2821 gtattgagac accagcattt gcttgggtag ataaagatat gagtaagaat aaaggcagtg
     2881 aatattatgt tggtaaatac tattctccaa caggaggagt accagaaata ttttcaaagc
     2941 agatacctgt aaaagaaagg tacaaaaaaa tatttataga cccaatttac tctctacctt
     3001 tatttagatt agtttataat gattctgtga tatcttccca tcagtggtta tggggaactt
     3061 tgaagattaa ggatgaagtt ggaagtagaa tgatgaaaga agtattatat aatacaccac
     3121 ctatgtatta tatagataga actgaatggg aaaaacataa agatgaaata atctcaaaca
     3181 ataaagtatg gtcagcgttt aataagaaag ctattaaaaa agaaatgaca gactttaaat
     3241 ttatttctga ggatagacta gttcaaatga ctgaatatgg agaagattta aaggtattag
     3301 ttaatttttc tcaaaaagac attaagtaca atgatgaagt cataaaagca aattctttgg
     3361 taatatatga tgctgatagt aaagtcatat ataaaccgga ataatagatt taatgaaaat
     3421 aaagattgtt taaatttcaa gtaaaaaata atataatatt catttagttt gtattaaagt
     3481 agtgactata ttaatctgga taattagtat agtcactatt atttatattc tttcctaaaa
     3541 gtaagtagta actgaatcgt gaataatcaa aaatggtaat ttgaaatagt ttttatgaat
     3601 agtattaata tatagatata gggagattga tgtgattatg tatgaaaata ataaggtaat
     3661 atataatttt gaaagatgtg aaaagctaga aaatgctctt tatttatctc aatttaatac
     3721 atataaaaac tttaagttaa cttctaaaaa aactgtaata aactcattag atacatctac
     3781 ttataatatg aatattcata gcataagtct cgttgatact atggaatgta tatcgtcaga
     3841 agatgaacaa atgacaggaa agaagttgat tttagttggc gatatagata ctgatgtaac
     3901 attagattat gtagtcaata aaagaaatag aagttttagt aaaaaaaata tacttaaatt
     3961 aaaaataccc tttagtacat ttatacaaat gcctagaaag atagaaaata aagataaaat
     4021 taatttaaag tatcttatac aagatattac ttcatctatt ttagatgata atttatttat
     4081 tagtgttact gcaattataa gttatgaaaa tagttccaag atagagtaat ctttaaatta
     4141 tagaaaggtg gatgcaatga gaataacgaa aactactttt aatgatgtat tttcaaatga
     4201 tgcaaatgga agtattataa aagtagaaaa atatgttgat aaaaaatgtg catctgtatt
     4261 tgagattttg acctacacta ttattgttac aaatacaagt aggtacaaaa ctggaaatat
     4321 atttttcaaa gattatattt ctaaatatat agagtttata aataatactg taaaagttaa
     4381 tggcattata aaacgtggat tagacccaca gcaaggtttt tacataggga gaatagatgc
     4441 aagttgtaaa aaaataatat cttttaagag tgtagtttta ccaaattctg cacataggat
     4501 tataaagaat agtgctaata tatactatta ttataagtgt aatctagata aattcccaac
     4561 aagaatatca atagaaagta atagagttta tactaatgta aataaaattg tattcaaaca
     4621 attgaatata agtaatactt taaaagctcc taaaaatcta agagatatat taaaagtaaa
     4681 tgtaaatagt aaaatatttg atgttaaacc tatgaaaaat cttataaaca aaggtagtaa
     4741 tttgaaatta tgtaactcga tagtttttgg gtgtatagaa gttgaaatag actatagttg
     4801 taaaaatagg agtaatttta aaacagtaaa taagtttaat gatattaaaa aagataagta
     4861 ttataaaaat gatatacaaa ataacaatga aaatataaac gattgtaaaa agcaaataag
     4921 ttttggtgat aataaggtaa aaaaaataac aaaaactttt ggattttctt gtttcatttg
     4981 ttctccagtt ggaattattt atgaagatat gaaaaatata aatataaaaa ttgaacatac
     5041 atcaataaat gaattaaatc cagaagaatt atttgtaaat acatcacttt tattgtatta
     5101 ttaagtattt taaagctaaa acttaaactt attaaaatag catttggtta aaggaaaata
     5161 gatattgata tatttatcat atatataaat gattaattaa
//
LOCUS       DACTZW010000150         5132 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.153, whole genome shotgun sequence.
ACCESSION   DACTZW010000150 DACTZW010000000
VERSION     DACTZW010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5132
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.153"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(13..408)
                     /locus_tag="JAM15_18445"
     CDS             complement(13..408)
                     /locus_tag="JAM15_18445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HAT6800225.1"
                     /translation="MIFKKHKETILYLFFGAFTTLVNIVSYLFFTRVILFNFMVANAL
                     AWILAVLFAYVTNKFFVFESRRVELKFLFKEFLSFVSFRLISGIIEMIIMYIMIDLLF
                     INDVIVKIFTNIIVIVLNYLFSKMIIFRK"
     gene            640..3051
                     /locus_tag="JAM15_18450"
     CDS             640..3051
                     /locus_tag="JAM15_18450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp84"
                     /protein_id="HAT6800226.1"
                     /translation="MRKYKSKKLSKLLALLTVCFLIVSTVPVSAENNKTLDGVETAEY
                     SESYLQYLEDVKNGDTAKYNGVIPVPHEMEGTILQNKGRSALPSSYKASASYNSINLG
                     LTTPAKNQGDLNTCWAFSGMSTLESYLKLKGYGTYDLSEEHFRWWSTGGTHGWNLTDM
                     TGSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQGATRPSNMDTASTQFNVTDVIRLNK
                     DKNTVKNAIMQYGSVTSGYAHYSTYFNEDETAYNCTNKRATLNHAVAIVGWDDNYSKD
                     NFASDVKPESNGAWLVKSSWGEFNSMKGFFWISYEDQTLLTDTDNYAMKSVSKPDSDK
                     KMYQLEYAGLSKIMSNKVTAANVFDFSRDSEKLDSVMFETDSVGAKYEVYYAPVANGV
                     PQNNSMTKLANGTVSYSGYINVSTNSYNLPKGKGAIVVVIDNTANPNKEKSTLAYETD
                     IDAYYLYEAKANLGESYILQNNKFEDINTYSEFSPCNFVIKAITKTSSGQATSGESLT
                     GADRYETAVKVSQKGWTSSQNAVLVNGDAIVDALTATPFTAAIDSPILLTGKDNLDSK
                     TKAELQRLGTKKVYLIGGENSLSKNVQTQLSNMGISVERISGSDRYKTSISLAQKLNS
                     IKSVSQVAVANGVNGLADAISVGAAAADNNMPIILTNEKSELQGADEFLNSSKITKSY
                     IIGGTATLSSNLESKLSNPTRLAGSNRNETNAKIIDKFYPSSDLKYAFVVKDGSKSQG
                     DLIDGLAVGALGAKTDSPVVLVGNKLDESQKTVLKSKKIETPIRVGGNGNESAFNELN
                     TLLGK"
     gene            3348..4925
                     /locus_tag="JAM15_18455"
     CDS             3348..4925
                     /locus_tag="JAM15_18455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp5"
                     /protein_id="HAT6800227.1"
                     /translation="MKAPKTILTILTIALTLSSISIIPSYALTEEKLIGNGRYETAVK
                     ISQKAYSSSSNVVLVNDNSLADALSATPFAKAKGAPILLTESDKLDDRTEKEIKRLGA
                     KDIYLIGGAVVLNKDIENKLKSNGLNVERINGKDRYETSLILANKLKDIKDIKEVAVV
                     NGEKGLSDAVSVGAPAAQNKMPIILSSPKDGVEAFDKFIRDEKVIKAYVIGGTNSVSR
                     AVEKSLPNAERVSGKDRNETNAKVIEKFYTDTNLSNLYVTKDGSKNENQLIDSLAVGV
                     LAAKNESPVVLVGNKLNTKQRDILSTKKLNTITQVGGNGNEEAFDEIKSLQEKTVFEA
                     KTVEELTDMINIASPNDIINFKPKENTVNEAFRMVTNKPITVNIKGDCSKTLTVDMPN
                     GEVNNYATLVNVIVRNIGEGGFNNHDTITILSVRDKNGRVIENTRNSDIDTLMILASA
                     NDTKLINDGYIGKLIDNSSNSDITNNGTIDKKVNQVENLEAKVDSIEKAIDSISQKVN
                     KIQDILDKIGFLKKFLS"
BASE COUNT         2110 a          652 c          874 g         1496 t
ORIGIN      
        1 ttagtctgtt ttttatttcc taaaaattat catcttacta aataaataat ttaaaactat
       61 aacaattata ttagtaaaaa tcttcactat aacatcattt ataaaaagta aatcaatcat
      121 tatatacata ataatcattt ctataatacc ggaaatcaac ctaaaactaa caaaagacaa
      181 aaactcttta aataaaaact ttaactcaac tcttctgctt tcaaacacaa aaaacttatt
      241 agtaacataa gcaaataaaa cagcaagtat ccatgccaaa gcatttgcaa ccataaaatt
      301 aaataaaata actctagtaa aaaataaata agaaactata tttacaaggg tagtaaatgc
      361 tccaaaaaat aaatataata ttgtctcttt atgtttttta aaaatcaaat ataaccctcc
      421 caaactaatc aaatataact attcttgaag attctaacat actttagtat aacatatcca
      481 ttaattaatg aatcaataca ttataaaata tcataaaaaa taaaattata gcactataca
      541 attagtacac acttataatc catattttat caaaataaaa tatgacctcg atttagaaat
      601 ctgatataat aaaaattaaa tacatacaag ggggtaaata tgagaaagta caaatcaaaa
      661 aaattgtcaa agctactggc attgttgaca gtttgctttt taatagtgtc aacagtacct
      721 gtatcagcag aaaacaataa aacactagat ggagtagaaa ctgcagaata ctctgaaagt
      781 tatcttcaat atctagaaga tgtcaaaaat ggagatacag caaaatataa tggagtaata
      841 ccagttccac atgaaatgga aggtacaata cttcaaaata agggaagaag cgctcttcca
      901 tcatcataca aagcgagtgc atcgtacaat tcaataaact tgggattgac tacaccagca
      961 aaaaatcagg gtgaccttaa tacatgttgg gcattttcag ggatgtcaac tttagagtca
     1021 tacctaaaac taaaaggtta tggaacttat gacctttcag aagagcactt tagatggtgg
     1081 tcaactggag gaacacatgg atggaatcta actgatatga caggaagctc aaatgtaaca
     1141 gctataggat accttacagc atgggcaggt cctaaactag aaaaagatat accatacaac
     1201 cttaaatctg aggcacaagg agcaactaga ccttcaaata tggatactgc atctacacag
     1261 ttcaatgtga cagatgttat acgtcttaat aaagacaaaa acactgtaaa aaatgcaata
     1321 atgcaatatg gttctgttac gtcaggatat gctcattact caacttattt taatgaagat
     1381 gaaacagcat ataactgcac aaataagcgt gcaactttaa atcacgctgt agcaatagta
     1441 ggatgggatg ataattattc aaaagacaac tttgcatctg atgtaaaacc agaatcaaat
     1501 ggagcgtggt tagtaaaaag tagctgggga gaattcaact cgatgaaagg tttcttctgg
     1561 atttcttatg aagatcagac cttgttaaca gatacagata actatgcaat gaaatcagta
     1621 tcaaaaccag atagtgacaa aaaaatgtac caacttgaat atgctggtct tagcaagata
     1681 atgtcaaata aagtaactgc agcaaatgta tttgatttca gtagagactc tgaaaaactt
     1741 gactcagtta tgtttgaaac agactctgta ggagcaaaat acgaagtata ttatgcacca
     1801 gtagcaaatg gagttcctca aaacaactca atgacaaaac ttgcaaatgg aacagtatca
     1861 tactctggat acataaatgt gtctactaac tcttataacc ttccaaaagg taaaggtgca
     1921 atagtagtag ttatagacaa cacagcaaat cctaataaag aaaaatcaac tttagcatat
     1981 gaaactgaca tagatgcata ctatctatat gaagctaaag caaacttagg tgaaagttac
     2041 atacttcaaa acaataaatt tgaagatata aatacataca gtgaattttc tccttgcaac
     2101 tttgttataa aagctataac aaaaacatct tctggacaag ctacttcagg agaatcttta
     2161 actggagcag atagatatga aacggcagtt aaagttagtc aaaaaggatg gacttcttca
     2221 caaaatgcag tattagtaaa tggagacgca atagtggatg ctttaacagc tacaccattt
     2281 acagcagcaa tagactctcc aattcttttg acaggaaaag ataacttaga ttcaaaaact
     2341 aaggcagagt tacaaagatt aggaactaaa aaagtttatc taataggtgg agaaaattct
     2401 ttaagcaaga atgtacaaac tcaacttagt aatatgggta tatcagtaga aagaatttca
     2461 ggtagtgata gatacaagac tagtatatct ctagctcaaa agttaaatag tataaaatct
     2521 gtttcacaag ttgcagtggc aaatggtgta aatggacttg cagatgcaat aagtgttggt
     2581 gcagcagctg ctgataacaa tatgccaata atacttacta atgaaaaaag tgagttgcaa
     2641 ggtgctgatg agtttttaaa ttcatctaaa ataactaagt cttatataat tggtggaaca
     2701 gctactttat catcaaattt agaaagtaag ctttcaaatc caacaagact tgcaggaagt
     2761 aatagaaatg aaactaatgc taagataata gataaattct accctagttc agatttgaaa
     2821 tatgcttttg ttgttaaaga tggttcaaag agtcaaggag acttgataga tggattagca
     2881 gtaggagcat taggtgctaa aactgattca ccggtagttc tagttggaaa taagttagat
     2941 gaaagtcaaa aaactgtact taagtctaag aaaatagaaa ctcctattag agttggtgga
     3001 aatggaaatg aaagtgcttt taatgaacta aatactcttt taggaaaata gtgaatggaa
     3061 agatagtaag gatatacatt ttattattaa aaaatattca atagaagttt ataaatataa
     3121 aataacaaaa aggggtgtct caaaatgaac tttttagttc atgaggcact cttttttgtt
     3181 gttttatatt tttatcattt aaataatgaa aaataggctt gtctatattt ttagatagtt
     3241 ttcttattat tgatgaaaaa tgtaataatt ttaaactgta aaatagtgta aagttatttt
     3301 ataatataaa tatagtaaga ttttaaacaa aataaggggg aataataatg aaagcaccaa
     3361 aaactatttt aacaatactg acaatagcgc ttactttaag tagcatttct ataataccat
     3421 catatgcact tacagaggaa aaattaatag gtaatggtag atatgaaact gctgtaaaga
     3481 taagtcaaaa ggcatacagt tctagttcta atgtagtgct agttaatgac aattcattag
     3541 ctgatgcact ttcagctaca ccatttgcaa aggctaaagg agcaccaata cttttgacag
     3601 aaagtgataa gctagatgat agaactgaaa aagagataaa acgtctagga gctaaagata
     3661 tttatttgat aggaggtgct gttgtactta ataaagatat agagaacaag ttaaaaagta
     3721 atggacttaa tgtagaaaga attaatggta aggatagata tgaaacttca ctgattttgg
     3781 ctaataagct taaggatata aaagatatta aggaagttgc tgtagtaaat ggtgaaaaag
     3841 gattaagtga tgctgttagt gttggagcac cagcagctca aaataagatg cctataattt
     3901 tgtctagtcc taaggacgga gtagaagcat ttgataaatt tataagagat gagaaagtta
     3961 taaaagcata tgtaattgga ggtacaaatt ctgtttcaag agctgtagaa aaaagccttc
     4021 ctaatgcaga aagagtgagt gggaaagata gaaatgagac taatgctaaa gttatagaaa
     4081 agttttacac tgatacaaac ttaagtaatt tatatgtaac taaggatggt agtaaaaatg
     4141 agaatcaact aatagactcg ttagctgttg gagtattggc tgcaaaaaat gagtctcctg
     4201 ttgttttggt tggtaataaa ttaaatacaa aacaaagaga tatacttagt actaaaaaat
     4261 taaatactat aacacaggta ggtggaaatg gaaatgaaga agcttttgat gaaattaaga
     4321 gtttacaaga aaaaactgtg tttgaagcaa aaactgttga ggaattaact gatatgataa
     4381 atatagcaag tcctaatgac attataaact ttaaaccaaa agagaatact gtaaatgaag
     4441 cttttagaat ggtaacaaat aaaccaataa ctgtgaatat aaagggtgat tgttcaaaga
     4501 ctcttacagt agatatgcct aatggtgaag tgaataacta tgctactttg gtaaatgtta
     4561 tagttagaaa tattggagaa ggtggattta ataaccatga tacaatcact atattgtcag
     4621 ttcgtgacaa aaatggtaga gttatagaaa atactagaaa ttcagatata gatacgttga
     4681 tgatattagc ttctgctaat gatacaaaat tgattaatga tggatatata ggaaagctta
     4741 tagataattc atctaatagt gatataacta ataatggtac tatagataaa aaagttaatc
     4801 aagttgagaa tttagaggct aaagtagatt caattgaaaa ggctatagat tctataagtc
     4861 aaaaagtcaa taaaatacaa gatatactag ataagattgg atttctaaag aaatttctta
     4921 gttaagaata tgtatattta agtgaagtgt gtgttgtaat tgttctaaag ttatatagtt
     4981 aaacaggttt atatacaaac agacttatag ataaatatgt agtttagtat atatttgaat
     5041 aagctttggg gaggtaacat ggggattgga attgaatgta acaaaaaaat aaataaaagt
     5101 attgacaaaa ctagaataaa gaaaaataat ct
//
LOCUS       DACTZW010000151         5017 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.154, whole genome shotgun sequence.
ACCESSION   DACTZW010000151 DACTZW010000000
VERSION     DACTZW010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5017
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.154"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            81..692
                     /locus_tag="JAM15_18460"
     CDS             81..692
                     /locus_tag="JAM15_18460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HAT6800228.1"
                     /translation="MINDIKNKFKNYKPYINGYKNMKRASVLIPIVEINNTHYILFEV
                     RSKNLKHQPSEISFPGGKIESGETPYEAVIRETCEELGTFSDNIEVISSLDLLITPVK
                     FIIHPYLGYIKNINNLNINKDEVDHTFLVPIKYLLENPPNTYSNTVKVFPDENLPYGS
                     IPNQKDYKFESGSYPILFYKYKDYVIWGMTAKILENFLNFLSE"
     gene            990..1328
                     /locus_tag="JAM15_18465"
     CDS             990..1328
                     /locus_tag="JAM15_18465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3784 domain-containing protein"
                     /protein_id="HAT6800229.1"
                     /translation="MFAVGFVVIIALAFFILSVLLFNGKASMLLAGYNSMSKKEKARY
                     DKKKLCRSSSIVTFIVSIMLFIMAFLGYRIESGQMDEKKMVPFSIIFIIVILSSVFFN
                     ILYSNKKCKK"
     gene            complement(1735..3171)
                     /gene="miaB"
                     /locus_tag="JAM15_18470"
     CDS             complement(1735..3171)
                     /gene="miaB"
                     /locus_tag="JAM15_18470"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HAT6800230.1"
                     /translation="MSKRKQVTIPIEKIQEQDKYIEQIHRQNEEYFNRTGKRKLVFTQ
                     TFGCQMNEHDSEKLCSMLEEMGYQMSMMVEESDLIIYNTCAVRENAELKVYGNLGQLK
                     HLKGKNPDMKIAVCGCMMQQPHVVEELRKKYKHVDLIFGTHNLYKFPQLLTESINSDK
                     MLVDVWDVDGEVIEGLRSNRKFELKAFVNIMYGCNNFCTYCIVPYTRGRERSRTPEDI
                     INEIKELVANGTKEITLLGQNVDSYGKTLENPVSFSELLRKVNDIEGIERVRFMTSHP
                     KDISDEVIYAIRDCDKVCEFLHLPIQCGSSSLLKKMNRHYTKEYYLEIIEKAKKEVPG
                     IAFSTDLMIGFPGETEEDLLDTLDVVEKVRYDSAFTFIYSKRQGTPAAKMENQIPEDI
                     KHDRFNRVLEAVNRISAEINDGYKDRIVEVLVEGRSKNNENKFAGRTRQNKLVNFEGG
                     NDDLIGKLVMVKITEPRTFSLNGILVNN"
     gene            complement(3419..4855)
                     /locus_tag="JAM15_18475"
     CDS             complement(3419..4855)
                     /locus_tag="JAM15_18475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp28"
                     /protein_id="HAT6800231.1"
                     /translation="MKFYKRILTLTLSISFVFANIQLVDAISSVEKIQGKNKYEIAGK
                     IADKNAYKTAILINTSNSIADGLSASGLAGALNAPILLTEKNTIPTETSARLKNVSKV
                     YIIGGTYSISTSVENSLKSKKMKVVRIKGNDRIKTSYNVAKEINSIKKVNTVMLTNAY
                     KGEADSISIASVAARDKAPIILTNGQSIPFSTSGLKSYVIGGTASMSTTLVNNTKSTR
                     LGGSTRFETNKAIINKFYKDAREFYIAGAYELTNALVGSSLSKHGPMVLVNDGSNKSI
                     LKNAKKITSIGYIDSNIVQQCLNITNGIGDINTGVVKNVKPTTKTIKDGMYKVGKDIS
                     AGEYLITSNSGSYASYYEVTSDSTGNADSILSNDIFSGTRYITLKNGQYIKIEDSTMT
                     LAKYAKAQKAKNGKFGNGMYKIGLEIPAGEYIIMSNSSDAYYEVRNDSLGNAEGIVTN
                     DTFSGRRYITVEEGQYLILNDCYLIENE"
BASE COUNT         1707 a          760 c          542 g         2008 t
ORIGIN      
        1 taattagata aatcataatt atatattatt gttaaaactc aattatataa tttttaataa
       61 tattatttta ggaggtaaaa atgataaacg atattaaaaa taaattcaaa aattacaaac
      121 catatataaa tggatacaag aatatgaaga gagcatctgt tttaattcca atagtagaaa
      181 taaataacac acactatata ttatttgaag ttcgctcaaa aaatttgaag catcaaccta
      241 gcgaaatttc ttttccaggt ggtaaaatag aatcaggtga gactccatat gaagctgtta
      301 ttagagaaac ttgtgaggaa cttggaactt ttagtgacaa tatagaagta atatcaagtc
      361 ttgacctcct tataacacca gtaaagttta tcatacatcc atacttagga tatataaaaa
      421 atattaataa tttaaatata aacaaggatg aagttgacca tacttttttg gttcctataa
      481 aatatctttt agagaatcct ccaaatactt atagtaatac tgtaaaagtt tttccagatg
      541 aaaatctacc atatggttca attccaaacc aaaaagatta taaatttgaa agtggaagtt
      601 atcctattct gttttataaa tataaagatt atgtgatttg gggaatgaca gcaaaaatac
      661 tagaaaactt tttaaatttt ttatcagaat aacactcata ataaatcatc aaaactttta
      721 cataagaaat ttataaaagt ttctaaattt aacaattcta aaatatcaat aactatattt
      781 tgtagcactt ttttatttta ttattgtttg aatatttgat ggttttcaat gcaatttcaa
      841 cataaatact atgtattagt gtatactgtt gatgaattaa agtatgataa tctatttaat
      901 aaagtatgaa gtaaatgatt ttaatgtgtc tttatggtaa aattactaat aagtaataaa
      961 attaattaaa atatatggag gtgcttataa tgtttgctgt aggatttgtt gttataattg
     1021 cacttgcctt tttcatttta agtgtactat tatttaatgg aaaagccagt atgctactag
     1081 caggttataa ctctatgagt aagaaagaaa aagcacgata cgataaaaaa aaattatgta
     1141 gaagttctag cattgttact tttattgtct ctataatgct atttattatg gcatttttgg
     1201 gatatagaat agagagtggt caaatggacg aaaaaaaaat ggttcccttt tctataatat
     1261 ttataatagt catactttcc agtgtatttt ttaatatcct ctactctaac aaaaaatgta
     1321 aaaaataaat agttgtaagt tgagcagtta attataaaag attgactgct ttttcatgta
     1381 tattgactac tcttattaaa tattttaaca tttaaaaatc tatgtaaaaa taatgaatat
     1441 agtacaaact tctaataatg attttacctt tgtggttaca gtccactata tataatttaa
     1501 tatgataaca tggaattact aatgacaact aagtaagctt ttataaaata taataaaaca
     1561 aaaatagatg tacaatgaaa ttatatctta tatcaaattt atttttatta atagcaaaaa
     1621 cttacattag cataacatat gacaaattcg cttaaaataa aaatttttaa tataatttgt
     1681 tctatagtac atctatttcg attagtttac ataattttat tattttgtac aatattaatt
     1741 atttactaat atcccattta atgaaaaagt tctaggttca gtaattttga ccataactaa
     1801 tttaccaatt aaatcatcat ttccaccttc gaaatttacg agtttatttt gtctagttct
     1861 accagcaaac ttattttcat tatttttact tcttccttca actagaactt caactattct
     1921 atctttatat ccatcattta tttctgcaga aatcctattt acagcttcta acaccctatt
     1981 aaatctatca tgctttatat cttctggtat ttgattttcc attttagcag caggagttcc
     2041 ctgtctttta gaataaataa atgtaaaagc tgaatcatat ctaacttttt caaccacatc
     2101 taaagtgtcc aataaatctt cttctgtttc tcctgggaaa ccaatcatta agtctgtaga
     2161 aaaagcaata cctggaactt cctttttagc tttttctatt atttctaaat aatattcctt
     2221 tgtataatgt ctattcattt ttttcaaaag gctactgctt ccacattgta ttggtagatg
     2281 taaaaactca cacaccttat cacaatctct aattgcgtat attacttcat cagatatatc
     2341 ttttggatga gatgtcataa atcgaaccct ttcaattcct tctatatcat tcacttttct
     2401 taaaagttct gagaatgaaa ctggattttc aagtgtctta ccataagaat ctacattttg
     2461 tccaagtaaa gtgatttctt tcgttccatt tgcaacaagc tcttttatct cgttaattat
     2521 atcttcagga gttctacttc tttctcttcc tcttgtgtat gggactatac aatatgtgca
     2581 gaaattattg catccataca ttatatttac aaatgctttt aattcaaatt ttctattact
     2641 tctaagacct tctattactt ctccatccac atcccataca tccactaaca ttttgtcaga
     2701 atttattgat tctgtaagta attgcggaaa tttatataga ttatgtgttc caaatataag
     2761 gtctacatgt ttatattttt ttcttaattc ctctacaaca tgtggttgtt gcatcataca
     2821 tccacataca gctattttca tatctggatt ttttcctttt agatgtttta attgtcctaa
     2881 gttaccatac acttttagct ctgcattttc tctaactgca caggtgttat atattattaa
     2941 atcactttct tcaaccatca ttgacatttg gtatcccatc tcttctaaca ttgaacataa
     3001 tttttctgaa tcatgttcat tcatttgaca cccgaaggtt tgagtaaaca cgagttttct
     3061 ctttccagtc ctgttgaagt attcttcatt ttgtctgtgt atttgttcta tatatttatc
     3121 ttgttcttgt attttctcta taggtattgt tacttgtttt cttttgctca cgtctattcc
     3181 tcctagttaa tttcttatat tacacataac cttaattata tcaaataaga aaaatctttt
     3241 aaagatatta ttatttttct agttgtgttt taatagtaaa tctaatgatt tatatatact
     3301 atatttctaa aatataaaat catataatta ttataataat aaaaagatgt tttaaattaa
     3361 aacttaaaac atctttcctt aaataaaata tatgatttac tattaaatac aattacatct
     3421 attcattttc aattaaataa caatcattta atattaaata ttgaccttcc tcaaccgtta
     3481 tatatcttct tcctgaaaaa gtatcattag taactattcc ctctgcatta cctaagctat
     3541 catttctaac ttcataatat gcatcagaag aatttgacat tataatatat tctccagcag
     3601 gaatttctaa tccaatttta tacataccat ttccaaactt accattcttg gccttctggg
     3661 ctttagcata ctttgctaat gtcattgttg aatcctcaat tttaatatat tgaccattct
     3721 ttaaggtgat atatctagtc ccactaaaaa tatcatttga aagtatacta tcagcattac
     3781 ctgtactatc acttgtaact tcataataag aagcataact tcctgagttt gaagttatta
     3841 agtattcacc tgctgatata tcttttccaa ccttatacat tccatctttt atagtctttg
     3901 tagtaggttt aacatttttt acaaccccag tattaatatc tccaattcca tttgttatat
     3961 ttaaacactg ttgtactata tttgaatcta tatatcctat agaagttatc ttcttagcat
     4021 tttttaaaat gcttttattg ctaccatcat taactaaaac cattggacca tgttttgata
     4081 aagaagatcc tacaagtgca tttgttaatt cataagctcc agctatataa aactctctag
     4141 catccttata aaacttattt attattgctt tattagtttc aaaacgagta ctccccccta
     4201 gtctagtaga tttagtattg tttactaaag tggtactcat tgaagctgtt cctcctatta
     4261 cataagactt taaaccacta gttgaaaaag gtatactttg tccattagta agaattattg
     4321 gtgctttatc tcttgctgct acagatgcaa tacttataga atctgcttct cctttatatg
     4381 cattggttag cataacagta ttgacttttt ttattgaatt tatttctttt gcaacattat
     4441 aacttgtttt tattctgtca tttcccttaa ttcttacaac tttcattttc ttagatttta
     4501 atgaattttc gacagatgta ctaatagaat atgttcctcc aattatataa acttttgata
     4561 cattttttaa tcttgcagat gtctcagttg gtatagtatt tttttcagtt aatagtatag
     4621 gggcatttaa agctcctgct agtccacttg cacttaatcc atctgcaata gagttactag
     4681 tattaattaa tatagcagtt ttatatgcat ttttatctgc tattttacct gcgatttcat
     4741 acttattttt tccttgtatt ttttctacag atgatattgc atctactaat tgaatatttg
     4801 caaatacaaa agaaatactt aaagtcaatg ttaatattct tttatagaat ttcataataa
     4861 aattgtcccc ctcataataa atttttaata tataaataca tattcttaaa ttagttatgt
     4921 acttaacaaa cttatgtaaa attgcaaatt atattaagca tattacaaat aaatattaat
     4981 acaattattc atttagctat aattgtattt acattta
//
LOCUS       DACTZW010000152         4980 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.155, whole genome shotgun sequence.
ACCESSION   DACTZW010000152 DACTZW010000000
VERSION     DACTZW010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4980
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.155"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            708..4850
                     /locus_tag="JAM15_18480"
     CDS             708..4850
                     /locus_tag="JAM15_18480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF11 domain-containing protein"
                     /protein_id="HAT6800232.1"
                     /translation="MATVSGQIVFDRNRSATIDSGDSGIANIPVVLQDIATGVRLVVL
                     TDASGNYVFTNVPNGNYRIVEAFGTTGGVPTPGNFATAIVGPVPIAEMPPISSVTNPP
                     IGSTNLDGTTPNTLLITVAGSDIINQNILNGPVIYTPIENILDSCVSVSNINLITDAD
                     NGTFGFFPPGTPSNTGPEIEPYPNVTPDFTYVVPDPTKFTPLDGEYTVQNIMTNAMSN
                     VIGAWWRIADHTTGNETGRMMVVNGFNPGAVFFKSTVQVTPNTNYLFSTWILNLFKVT
                     GYPPPQLGVRIFDQNNNILYQATLGAQIPVNTNAPEWKEVGTVINSQNNNQLTVEFFS
                     EGESAIGNDYAIDDVSLREIAVPTFTPIKTSNTETANVGDIITYTVTLDNTCDSPLTN
                     VFFRDLIPNGLEFIPGTVTVDGVSVPGVDPNTGFPLPDIGGGIGVEVTFDVVVESIPN
                     PNPTNNIATIDYSYTPVEGGIPNDFSVDSNPVPVEVISADVEVTKLSEPTIVNPGEEL
                     IYTIKVVNNGPFPSENVVLTDDVPASIINPEYSLDGGVTFQPWTGSLNIGTLEVGETR
                     VIIIRGIVNPSTVGIITNTAVVSSTTADPNLNNNTSTIETEVNLLADILVMKTAEPNS
                     AVPGTLLKYTIQVENLGPANAENVILNDDIPASIINPEYSLDGGASFQPWNGSLNIGT
                     LNSGISLTVLIQGTVSLNSSEYIVNTATVSSTTPDPDLSNNISTIITPVNPQAGISII
                     KVADEDVAVPGEEFVYTIEIFNEGPSNATNVVLTDDIPDVILNPEYSLDGGATFQPWN
                     GSLNIGTVAPGQLIRIIIKGLVSSTATGDITNTAEVSADVPEPVTDSSTVTTPIVPSA
                     DIEVIKTSNMDTAVPGETFSYTITVINLGPSAAQSIVLTDDIPDVILNPEYSLDGGVT
                     FQPWNGNFSIGTLDAGEIRSIIIRGTVSQTAVGTIINTATISSTTPDPNPDNNTSTDE
                     TDISPLADISVIKGNEPVAIPGGRFIYGIEIANAGPSFAENVTLTDNIPASILNPEYS
                     IDNGVTFQPWNGSLNIGTLDAGEIRNIIIRGTVSQTAIGTIINTATVSSTTPDPNLNN
                     NTSTSEAEVSSSADISVVKRSNQTVVVPGDVLDYTIEVRNAGPSTAQNVTLTDNIPAS
                     ILSPEYSIDNGVTFQPWNGSLSIGTLDAGEIRNIIIRGIVSQTAIGTIINTATVSSTT
                     PDPNPDNNTSTSEIDISSSADISVIKLANKTEACVGEQIDFVIVVSNAGPENAQNVTL
                     IDNVSDKLKKAVFSLDRGVSFQPWTGSLNIGTLPAGTLRVILLRGIIKSTCLDRLTNI
                     AEVTSTTPDSNLNNNISRVQVEIKQCCCNDCCCNNCSNCCCNDCGCKDYCCNCCKNDF
                     WC"
BASE COUNT         1927 a          726 c          835 g         1492 t
ORIGIN      
        1 aattacaata ttatattgat tattcaaaat tatatataaa attcagaaga acattttagt
       61 ttacataata aaaataaagt aaactaaaat tattgatttt agattaaagt accagattaa
      121 gcatttaagt agattttaag cttaatttga ttagaaaggt acaaactatc accgaaaaaa
      181 attaaaccca tttaaaaagc aatataaaag cttgttattt tcgagaaaaa tagaccctct
      241 aaactcaatt agataaaaat aaaatacaga aaattatatc tctgaatatc tcaagtaatt
      301 aagtttaaat tttacgatat tttgtttgat gatttataat ataaaagcat attcttaatc
      361 ttctcaaatt aaaaagagta aaaaataaca aaaaaatcac tgacatttca ctgacaaatt
      421 gtaattttgt tattataaat acattgaaaa tacttgatta ttgaaaaatg gcataaaata
      481 atacctttta tgccatttac tattgtttga tagtttttaa cttatgacat aagatatttt
      541 ttaacatata caataaaata taaaaaaatt gatattgcaa ataaaaaaaa tacatattag
      601 atgttataga aaaaaagcgc acttataggc ttaaaatgtc acataaaaga gtttcaaaga
      661 ataatatatt atgaacacaa attttgtaat cacaaaggag tgataatatg gcaacagtat
      721 caggacaaat agtttttgat agaaatagaa gtgctaccat tgattctggg gactcaggaa
      781 tagccaatat accagttgta ttacaagata tagcaactgg agttagactt gtggttctca
      841 cagatgcatc aggaaattat gtttttacta atgttccaaa tggtaactat agaattgtag
      901 aagcttttgg aactacagga ggagtaccaa caccagggaa ttttgcaaca gcgatagtag
      961 gtccagttcc aattgcagaa atgccaccta ttagttctgt gacaaatcct cctattggtt
     1021 caacaaactt agatggtaca acacctaaca cactattaat aacagtagca ggttcagata
     1081 taataaatca aaatatatta aatgggcctg tgatttatac acctatagag aatatattgg
     1141 attcttgcgt gtctgtatct aatataaacc ttattacaga tgcagataac ggaacattcg
     1201 gtttttttcc accaggtaca ccaagtaata caggacctga aatagaacct tacccaaatg
     1261 tgacgccaga ttttacgtat gttgtaccag acccaactaa gtttacacct ttagatggag
     1321 aatatacagt acaaaatatt atgacaaatg caatgagtaa tgttatagga gcttggtggc
     1381 gtattgctga ccatactaca ggaaatgaaa caggaagaat gatggtggta aatggtttta
     1441 atcctggagc tgtatttttt aaatcaacag tacaagttac acctaacact aattatttat
     1501 ttagcacttg gattttaaac ctttttaagg taacaggata tccaccacca cagctaggtg
     1561 taagaatatt tgaccaaaat aataatatac tatatcaagc aacattagga gctcaaattc
     1621 cagttaatac aaacgcacca gaatggaaag aagtaggtac tgtgattaat tctcaaaata
     1681 ataatcaact tacagtagaa ttttttagtg aaggagaaag cgccattgga aatgactatg
     1741 ctatagatga tgtttcttta agagaaatag ctgttccaac ctttactcca ataaaaacaa
     1801 gtaacacaga aactgctaat gtaggtgata taatcacata tacagttaca ttagataata
     1861 cttgtgatag ccctttaact aatgtatttt ttagggattt aattccaaat ggtttagagt
     1921 ttatacctgg aactgtaacg gttgatggag tatctgtacc aggagtagac cctaatacag
     1981 gttttccact tccagatatt ggaggaggaa taggggttga agtaactttt gatgttgtgg
     2041 ttgaaagtat tcctaaccca aatcctacta ataatatagc tactatagat tactcctata
     2101 cacctgtaga aggcggtata ccaaatgatt tttcagtaga ttctaatcca gttcctgttg
     2161 aagtaatctc agcagatgtt gaagttacaa aattatctga acctactata gtgaatccag
     2221 gagaggaatt aatatacact ataaaagtag taaataatgg accattccca tctgagaatg
     2281 tggttttaac agatgatgta ccagcttcta ttataaatcc agagtattca ttagatggag
     2341 gagtaacttt tcaaccatgg actggaagtt taaatatagg gacattagaa gtaggagaga
     2401 caagagttat tataattagg ggtattgtaa atccatcaac agtaggaatt ataacaaata
     2461 cagctgtagt atcttcaact acagcagacc caaaccttaa taataataca tctacaatag
     2521 agacagaagt gaatttatta gcagatattt tagtaatgaa aacagcagaa cctaattcag
     2581 ctgttccagg tactttattg aaatatacta ttcaagtaga aaacttagga ccagcaaatg
     2641 ctgaaaatgt aatattaaat gatgatattc cagcctctat tataaatcca gaatattcat
     2701 tggatggagg agcaagtttt caaccatgga atggaagtct taatatagga actttaaact
     2761 ctggaatttc attaacagtt ttaattcaag gaacagttag tttaaattct tcagaatata
     2821 tagtaaatac agcaacagtt tcttcaacta cacctgaccc agatttaagc aacaatatat
     2881 ctaccattat tacaccagtt aacccacaag caggtatttc tattataaaa gtagctgacg
     2941 aggatgtagc tgttccagga gaagaatttg tatatacaat tgaaattttt aatgaaggac
     3001 catctaatgc tacgaatgta gttttaacag atgatatacc agatgttatt ttaaatccag
     3061 aatattcatt ggatggagga gcaactttcc aaccatggaa tggaagtctt aatataggta
     3121 cagttgcacc agggcaatta ataagaatta tcataaaggg attagtaagt tcaactgcta
     3181 caggagatat tactaataca gcagaagtaa gtgcagatgt accagaacca gttacggatt
     3241 catcaacagt gacaactcct atagttccat cagcagatat agaagtaata aaaactagca
     3301 atatggatac agcagttcca ggagaaactt ttagttatac tataacagtt ataaatttag
     3361 gaccatctgc tgcacaaagt atcgttttga cagatgatat accagatgtt attttaaatc
     3421 cagagtattc attggatgga ggagtaactt tccaaccatg gaatggaaat tttagtatag
     3481 gcactttgga tgctggagaa ataagaagta ttataataag aggaacagtg agccagacag
     3541 cagtaggtac aattataaat acagcaacaa taagttcaac tacacctgac ccaaatccag
     3601 ataataatac ttcaacagat gaaacagata taagtccatt agcagatatt tctgtgataa
     3661 aaggcaacga accagttgct ataccagggg gaagatttat ttatggaatt gaaattgcaa
     3721 atgcaggacc atcttttgca gagaacgtaa ctttaacaga taatatacca gcttctattt
     3781 taaatccaga gtactcaata gataatggag tgactttcca accatggaat ggaagcctta
     3841 atataggtac tttagatgct ggagagataa gaaatatcat aataagggga acagtaagtc
     3901 aaacagcaat aggtacaatt ataaatacag caacagtaag ttcaactaca cctgacccaa
     3961 atctaaataa caatacttca acatcagaag cagaggtaag ttcatcagca gatatttctg
     4021 tagtaaaacg aagcaatcag actgttgttg taccaggaga tgtactagac tatacaattg
     4081 aggtgagaaa tgcaggaccg tctactgctc agaacgtaac tttaacagat aatataccag
     4141 cttctatttt aagtccagaa tattcaatag ataatggagt gacttttcaa ccatggaatg
     4201 gaagtcttag tataggcact ttagatgctg gagagataag aaatatcata ataaggggaa
     4261 tagtaagtca aacagcaata ggtacaatta taaatacagc aacagtaagt tcaactacac
     4321 ctgacccaaa tccagataat aatacttcaa catcagaaat agatataagt tcatcagcag
     4381 atatttctgt aataaaatta gcaaataaaa cagaagcatg tgtaggagag caaatagatt
     4441 ttgtaatagt agtatcaaat gcaggaccag aaaatgctca aaatgttact ttaatagaca
     4501 atgtttcaga taagcttaag aaagcagtat tttcacttga tagaggtgta agtttccaac
     4561 catggactgg aagtcttaat ataggtacac taccagctgg aactttaaga gttattctat
     4621 taagaggaat tataaaatca acatgtcttg atagattaac aaatattgca gaagttactt
     4681 caacaacacc agattcaaac cttaacaata atatatcaag agtgcaagta gaaataaaac
     4741 aatgttgttg taatgattgc tgttgtaaca actgtagtaa ttgttgttgt aatgattgtg
     4801 gttgtaaaga ttattgctgt aattgttgta aaaatgactt ttggtgttga ttttataaaa
     4861 taattttgta taccttaaat taaactgaaa taaaaaataa attcacatat gagtaaaata
     4921 ttttataaat attaataaat tttctatctt tgatatggac cacattcgta atactagtta
//
LOCUS       DACTZW010000153         4595 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.156, whole genome shotgun sequence.
ACCESSION   DACTZW010000153 DACTZW010000000
VERSION     DACTZW010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4595
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.156"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            210..1016
                     /locus_tag="JAM15_18485"
     CDS             210..1016
                     /locus_tag="JAM15_18485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAT6800233.1"
                     /translation="MGMILSTLGINLYLAPAKLLSGGVAGICVILYKLFGINQGISSF
                     LMNIPIFIIARKYFDNKFLLISFVNMLLFSLALGLTQDIAKYFPIDDTMLQCIYGGAL
                     TGIGMGLTFKARATAGGLDIIAAIMKRKYDIPMKNTFLFINFFVVCAGAFLFGAKLVM
                     YTLITMYIISFTMDIGKDCFDRKKSILLISNKYDEISKVIMNKMGRGVTFLEAEGAYT
                     QNKKKMIYCIISANEIGKFKDLIYDMDSEAFISVNNVEEVKGGGFKDKFL"
     gene            1143..1415
                     /locus_tag="JAM15_18490"
     CDS             1143..1415
                     /locus_tag="JAM15_18490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800234.1"
                     /translation="MLRERFVVRNHHNPHTSGCCGTGGEGCCGGDNHEHSHQHSHSHG
                     HEHEHVNGVGHDHNHDDGFSGTHEHSHEHTHTHGHEHSDGHTHEHK"
     gene            complement(1578..2150)
                     /locus_tag="JAM15_18495"
     CDS             complement(1578..2150)
                     /locus_tag="JAM15_18495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAT6800235.1"
                     /translation="MKTNNMKQAILSSATNLIAKNGVQNTSLADIAKDVNISKGTLYY
                     HYASKDDIIYDIADTHLEVITSAILNCVKNVKSKNSQIEMVNLILEKISTIESRGRVH
                     MYLICEAITSNNDLKERIRLKYIEWRTTLKSEIVESLEKYNSSENEQDAESFSFLLMS
                     IVDGLVVQSLLKTEKIPYENIASFLVNHWI"
     gene            2334..3176
                     /locus_tag="JAM15_18500"
     CDS             2334..3176
                     /locus_tag="JAM15_18500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAT6800236.1"
                     /translation="MDKIKLIVDSACDLPDDIIEKYNIEVVGLNVSFGEESYISGKEI
                     DNETFYRKMSESKVLPKTSCPSPDKFLEAYHCQEESVLVINISSGLSGTYNSALLAKD
                     MFEKEGNNKKVEVIDSLSGSIGIGQLVLKAAILIKEGKEIEEIVSIINKYKDNPPFFG
                     TLETLENAIKGGRINPIAGKIINTLNFKAIIQVADGVVTPIDKARGEGNSLKKLITLV
                     ESKIKDKEEKVLFIGHANCPEKAQKVREVMEKDVKYKDVVICEIGSVMGTYTSKGAIL
                     ITAI"
     gene            complement(3279..4355)
                     /locus_tag="JAM15_18505"
     CDS             complement(3279..4355)
                     /locus_tag="JAM15_18505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HAT6800237.1"
                     /translation="MKAQRLNAVLEQMKKDDISQMLVSDPTSIFYLTGVLIHPGERLL
                     ALYLNLNGNNKLFINELFPVSEDLGVEMVWFNDTQNPVEIITEHIDKNATMGVDKNWP
                     ARFLLNLIELGGGSKFVNSSYIIDTLRMCKDEEEKELMRIASKLNDKAMEQLKATVSG
                     ELTEKQLVGKLSKIYEDLGTDGFSFDPIIGFGPNGANPHGEPGNALVKPGDAIILDIG
                     CIKDNYCADMTRTVFYKEIPEKGREIFEIVLEANKRAEAIVKPGVRFCDIDAAARDYI
                     TEKGYGQYFTHRTGHSIGLEVHDKGDVSSINTDTVQPGMIFSIEPGIYLPGEFGVRIE
                     DLVLVTEDGCEILNKHDKEICVVG"
BASE COUNT         1677 a          591 c          715 g         1612 t
ORIGIN      
        1 atgcaagcat aaatatatta aaagaaggat taagactaat aacaattcaa aataaataac
       61 ttatgtaaga actgtaggaa ctacggggat agcttgtgga gaattagtaa gacatatttt
      121 agtatgcaaa attctatgaa gcaggaaccc tgtgacttta gtcatgggag gttcagaata
      181 acatattttt acaatatggt ctgattatat tgggtatgat tctatcaacc ttaggaataa
      241 atttatatct agcaccagcc aagttattaa gtggaggagt agctggaatt tgtgttatat
      301 tatacaaatt atttggtata aatcagggaa tatcaagttt cttgatgaac ataccaatat
      361 ttattatagc tagaaagtat tttgataata aatttttgct aataagtttt gtcaatatgt
      421 tactattttc tctagcactg gggctaacac aagatattgc taaatatttc ccaatagatg
      481 atactatgct acagtgtatt tatggtggtg cattaactgg tataggtatg gggttaactt
      541 ttaaagcaag agctactgct ggaggacttg atataatagc agccataatg aaaagaaagt
      601 atgatatacc tatgaaaaat acatttttat ttattaattt ttttgtagta tgtgcaggag
      661 ctttcttatt tggagctaaa ttggtgatgt acactttaat tacaatgtat ataatttctt
      721 ttactatgga tataggaaaa gattgctttg atagaaaaaa atctatactt ttaatatcaa
      781 ataaatatga tgaaatatcc aaagtgataa tgaataaaat gggtagagga gtcacttttt
      841 tggaggcaga aggtgcatat acacaaaata agaaaaagat gatttattgc ataatatctg
      901 caaatgaaat aggtaaattt aaagatttaa tttatgatat ggatagtgaa gcttttattt
      961 ctgtcaataa cgttgaagaa gtaaaaggtg gaggttttaa ggataaattt ctttaagatt
     1021 atatatgtta attatatatg ttaaaaaatg ccatatgtat tgagattata cctagttaga
     1081 tgtatactgt agttaatggg gtacatgaag tactcaataa tatactagga ggtataagaa
     1141 ttatgttaag agagagattt gtagtaagaa atcatcataa tccacataca agtgggtgtt
     1201 gtgggactgg aggagaagga tgctgtggag gagataacca tgaacattca catcaacatt
     1261 ctcacagtca tgggcatgaa catgagcatg taaatggtgt aggtcacgac cataatcatg
     1321 atgatggttt ttcaggtact catgagcata gccatgagca tacacataca catggccatg
     1381 aacattcaga tgggcataca catgaacata aataaaaaca ttttaaattt ataagagatt
     1441 tttattttgt gattccatga aggtttaaat aaaaattgaa tgttttaagt aaaaattatt
     1501 gagaataaat aagaaagtga actgttaaag tagataactt aaatagttca cttttattaa
     1561 ttatttaagt attaagttta aatccaatga ttaactaaaa aagaagctat attttcataa
     1621 ggtatttttt ctgtttttaa taaactttgg acaactaaac catcaactat tgacatgagt
     1681 aaaaaagaaa atgattcagc atcctgttca ttttcgctac tattatattt ttctagtgat
     1741 tcaacaattt cagatttaag agtagttctc cattcaatat attttaatct tattctttcc
     1801 tttaaatcat tatttgaagt aattgcctca caaataagat acatatgtac cctaccacga
     1861 ctttctatag tagatatttt ctctaagatt aagttaacca tttctatttg agaatttttt
     1921 gatttgacat tttttacaca gtttagtata gcactagtta taacttctaa atgagtatcc
     1981 gcaatatcat atataatatc atctttagat gcgtagtgat aatacaaagt acctttactt
     2041 atatttacat cttttgcaat atcagcaagg ctagtatttt gaactccatt tttggctatt
     2101 aaattggttg cagatgataa aatagcctgt ttcatattat ttgttttcat aaaacctacc
     2161 tttccatgta tatttataac aaattaataa cattataagc ttatgaatat ttattgtcaa
     2221 taaagcgaga atctatatct attgactttt tttcattcaa tatataaaat aataattaaa
     2281 tcggtcgtac gaccgactga ataaataaaa taatatctta tagtgaggtt aatatggata
     2341 aaataaaatt gatagtggac agtgcatgtg acttacctga tgatataata gaaaaataca
     2401 acatagaagt tgttggttta aatgtatctt ttggagaaga aagttatata tctggaaagg
     2461 aaatagataa tgaaactttc tatagaaaaa tgagtgagag taaagtacta ccaaaaacat
     2521 catgtccttc tcctgataaa tttttagaag cataccattg tcaggaagaa agtgtattgg
     2581 tgattaatat aagttcagga ttatctggga cttataatag tgcactttta gcaaaagata
     2641 tgtttgaaaa ggaaggaaat aacaaaaaag ttgaggttat agattcactt agtgggtcaa
     2701 ttggaatagg acaattagtg ttaaaagcag caatattaat aaaagaagga aaagaaattg
     2761 aagagattgt ttcaataata aataaatata aagataatcc tccatttttt ggaacacttg
     2821 aaactttaga aaatgctatt aagggtggta gaataaatcc aatagcagga aaaattataa
     2881 ataccttgaa ttttaaggcg ataatacaag ttgcagatgg cgttgtaact cctatagata
     2941 aggcaagagg tgaaggaaac agtttgaaaa agctgattac tttagtagag tcaaaaatta
     3001 aagataaaga agaaaaggtt ttatttatag gacatgctaa ttgcccagaa aaggctcaaa
     3061 aggtaaggga agttatggaa aaggatgtaa aatacaaaga tgttgtaatc tgtgaaattg
     3121 gttcagtgat ggggacatat acttcaaagg gtgcaatctt aataactgca atataaataa
     3181 tggattgaaa taaatcatag attgagaaat taaagccata taaaaatgtt taaaacattt
     3241 ttatatggct ttttaatttt atcaaattga ttttagaatt aaccaactac acatatttct
     3301 ttgtcatgtt tgtttaatat ctcacaacca tcttcagtaa caagtactaa atcttctatt
     3361 ctaactccga actcacctgg taaatatata cctggctcta tagagaatat cattcctggt
     3421 tgtacagtat ctgtatttat agaagataca tctcctttat catgaacttc aagtcctata
     3481 gagtgaccag ttctatgagt gaagtactgt ccatatccct tttcagttat gtagtcacga
     3541 gcagcagcat ctatatcaca gaatctaaca cctggtttta caatagcttc agctctctta
     3601 ttagcttcaa gaactatttc aaatatttct ctaccttttt caggtatttc tttatagaat
     3661 acagttcttg tcatatcagc acaatagtta tcttttatac aacctatatc taatattatt
     3721 gcatctcctg gtttcacaag tgcatttcca ggttcaccat gtggattagc tccattaggt
     3781 ccaaagccta taatagggtc aaatgaaaat ccatcagtac ctaggtcttc atatatttta
     3841 gataatttac caacaagttg tttctctgta agttcaccag aaacagtagc tttaagttgt
     3901 tccatagcct tgtcatttaa ttttgaagct attctcatta actctttttc ttcttcatct
     3961 ttacacattc ttaaagtatc tattatataa gatgaattta caaacttact tcctccacct
     4021 aattctatta agtttaataa gaatctagct ggccagtttt tatcaacacc catagtagca
     4081 tttttgtcta tatgttcagt tattatttct actggatttt gagtatcatt aaaccaaacc
     4141 atttcaacac ctaaatcttc tgaaactggg aataattcat ttataaataa tttattattg
     4201 ccatttaaat ttaagtataa tgctaataat ctttcacctg gatggattag tactcctgta
     4261 agataaaata tagaagtagg gtcacttact aacatttgag aaatatcatc ttttttcatt
     4321 tgttcaagta cagcatttaa tctttgagct ttcataataa tttcctccta atcaaaattc
     4381 aatacaaatc aattttagca ttattaaaca aaaaagagta tacttttctt ctagaaatat
     4441 aaaaaaagtt tgttatatat tttttatatt aagtttaatc tctacttttg cattaaatac
     4501 ggaagtaaaa tgacttttta ttgtgaaaat tctataaaag taataaatta agtctataaa
     4561 gttatgtatt ttatcttttt atatactaat gaaaa
//
LOCUS       DACTZW010000154         4551 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.157, whole genome shotgun sequence.
ACCESSION   DACTZW010000154 DACTZW010000000
VERSION     DACTZW010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4551)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4551)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4551
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.157"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            182..529
                     /locus_tag="JAM15_18510"
     CDS             182..529
                     /locus_tag="JAM15_18510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HAT6800238.1"
                     /translation="MHENKKNLLDGSLAQYNDTAVPKIPVFAGNDITSEVYYFKPNQV
                     LNAHRHPNGEQIFVFLKGEGKMKLGEHECDVKNGDTVFVPTGEWHEITNGSNEEMVAV
                     QITKINAGAEYRG"
     gene            complement(679..1728)
                     /locus_tag="JAM15_18515"
     CDS             complement(679..1728)
                     /locus_tag="JAM15_18515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAT6800239.1"
                     /translation="MFKKIVAIASSIIVSTICLTGCDFNSNDKKDESSSSKNLDKVTI
                     AEVTHSVFYAPQYAAITKGFFEDEGIKIDLINTQGADKTMAALISGEANVGLMGPEAS
                     IYVYNQNKNDYAVNFAQLTKRDGSFLVARKKMPNFSYNDLKGTEILGGRKGGVPLMTF
                     EYVLKEKGLTIGENLKAGNVNVRTDVQFGVMAGAFAGGEGDFTTAFEPTATAMEKEGS
                     GYIVTSIGKDSGEIPFTAYSTTRSYMKNNKDLIQRFTNAVYKGQLWVQQASSKEVAKA
                     MQPFFEDISLEDLTTVVDRYKSIDAWSQNPVLKEEGLKKLMTVMKEAKELDKEAPYKD
                     IVNTEFANNAIKNIK"
     gene            2114..2848
                     /locus_tag="JAM15_18520"
     CDS             2114..2848
                     /locus_tag="JAM15_18520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAT6800240.1"
                     /translation="MKQNKYDDDRFFNKYSKMERSTNGLAGAGEWHVLKKMLPDFKGK
                     RVLDLGCGFGWHCQYAVENGAISAVGVDISEKMLKEARNKTQLDNINYICMPIEDINF
                     PKDSFDVVISSLAFHYIQSFEDICKNISNCLSNKGNFVFSVEHPIFTAYGSQEWYCDK
                     DGNNLHWPVDRYFEEGVRKSNFLGEEVIKYHKTLTTYLNTLMKTGFEILEIIEPQPEE
                     KLLDTIPDMKDELRRPMMLLVSAKKR"
     gene            complement(2991..3482)
                     /locus_tag="JAM15_18525"
     CDS             complement(2991..3482)
                     /locus_tag="JAM15_18525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HAT6800241.1"
                     /translation="MNNQQQEVYKKLDELSIPYEAVNHPPVYTIEEMEELKTLHMEFV
                     VKNLFLRDAKGKEHFLVVLGKDKKADLKDIRQQIDSKPLSFASEERLQKYLKLTKGAV
                     TPFGILNDKEAVVKVVFDKDLLKMDKIGIHPNDNTATVFLKFEDMKKLIEENGNEIYY
                     VEV"
     gene            3831..4214
                     /locus_tag="JAM15_18530"
     CDS             3831..4214
                     /locus_tag="JAM15_18530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800242.1"
                     /translation="MSTDKVVGIIDEETAELAGIEYTGKIYASSGVIKHIKKKHRCQL
                     SKDIFNDIIDTIKMVLKSPEYIGSHPKKPGKSVEFIKKIDDYILVATELDTKKGYLYV
                     SSMYAIKEAKLESRVNSGRVKQYDG"
BASE COUNT         1684 a          574 c          623 g         1670 t
ORIGIN      
        1 ttattatatt atgttaattt ttttatatct tataaggatt atatttttct aactataaaa
       61 atagtattta cttatattta aaaataaaag aattttattc ctattgtgta aagtgagaat
      121 actattttct tatattggta taataatagt aaatctaata tagaaaagag gtatttctag
      181 tatgcatgaa aataaaaaaa atctattaga cggaagctta gctcaatata atgatacagc
      241 agttccaaaa ataccagtat ttgctggtaa cgatataact tcagaagttt attattttaa
      301 acctaatcaa gttcttaatg ctcatagaca ccctaatggt gaacaaatat ttgtgttcct
      361 aaaaggagaa ggtaaaatga aacttggtga gcatgaatgt gatgtaaaaa acggcgatac
      421 tgtatttgta ccaacaggag agtggcatga aattactaat ggaagcaatg aagaaatggt
      481 agccgttcaa attacaaaaa ttaatgctgg agcagaatac agaggataga tatataagta
      541 cagttagtac tttaatatct attttattat ataaacttta atctcaaata taaaaagagt
      601 cttttaaaag gctcttttta tatttttgtt aattttcatt ataaaaacaa gaaaatatct
      661 agctaaaact aatatatttt atttaatatt ttttatagca ttgtttgcaa actcagtatt
      721 tacgatatct ttataaggtg cttccttatc tagttcttta gcttctttca taacagtcat
      781 caatttcttc aaaccttcct cctttaatac aggattttga gaccatgcat ctattgattt
      841 atatctatct acaactgttg ttaaatcttc taaagatata tcttcaaaga aaggttgcat
      901 agccttagct acttctttgc tagatgcttg ttgaacccat aattgacctt tataaacagc
      961 atttgtaaat ctttgaatta aatctttatt gtttttcatg tatgatctcg tagtagagta
     1021 tgctgtaaaa ggtatttctc cagaatcttt tcctatagat gtaactatat atccactacc
     1081 ttctttttcc attgctgttg ctgtaggttc aaatgctgtt gtaaagtcac cctctccacc
     1141 tgcaaaagct ccagccatta caccaaattg tacatcagtt cttacattaa cattgcctgc
     1201 ttttagattt tctccaatag taagaccttt ttcttttaga acatattcaa aagtcattag
     1261 tggaactcca ccttttctac cacctaatat ttctgttcct tttaaatcat tgtaagagaa
     1321 attaggcatt tttttcctag caactagaaa actaccatct ctttttgtca attgagcaaa
     1381 gttcactgca taatcgtttt tgttttgatt atatacatat atagatgctt caggacccat
     1441 taaacctacg tttgcttcac ctgaaatcaa agctgccata gttttatctg caccttgggt
     1501 atttataagg tcaatcttta taccttcatc ttcaaagaat cctttcgtaa tagcagcata
     1561 ctgtggagca taaaaaacag agtgagtaac ttctgctata gttactttat ccagattttt
     1621 agacgaagaa gattcatctt ttttgtcatt agagttaaaa tcacatccag ttagacatat
     1681 tgtacttaca atgatagagc ttgctattgc gactattttt ttaaacataa taaatacctc
     1741 ccataagaca tacgaatagt atatagtatt aaaaatttat tgtagttgtt acaaaaatgt
     1801 atctatgctt ataatatttc tacaaaaact taataataat tttcagtttt atgtttagtt
     1861 tttttagtaa tatgtaatat tggataaatt atattgatta tttataaact aagtaataaa
     1921 attaaaataa tatcactttt ttgcctatta tatataagga aaaatttttt aataatataa
     1981 atcatattca tttatattat taaaaaattt gtttacagaa acttttatta ttttatataa
     2041 aagtgataaa aacttatatt ttgtgtttag tagagtgttg ctaagtgaat atatttaaaa
     2101 tggaggaaac tttatgaaac aaaataaata tgatgatgat agatttttta ataaatacag
     2161 taaaatggaa cgttctacaa atggattagc aggtgctgga gaatggcatg ttttaaaaaa
     2221 aatgttacct gatttcaaag gaaaaagagt tttagattta ggatgtggat ttggatggca
     2281 ttgtcaatat gcagttgaga atggagcaat ttctgctgtt ggagttgata tttcagaaaa
     2341 aatgttaaaa gaagctagaa acaagacgca acttgataat ataaattaca tatgtatgcc
     2401 tattgaagat attaattttc caaaagatag ttttgatgta gttattagtt ccttggcatt
     2461 tcattatatt caatcatttg aagatatatg taagaatata agtaattgtc tttcaaataa
     2521 aggtaatttt gtattttctg ttgaacatcc tatatttact gcatatggaa gtcaagagtg
     2581 gtactgtgat aaagatggca ataatctaca ctggccagta gatagatatt ttgaagaagg
     2641 agtacgtaag tcaaattttc taggagaaga ggttataaaa tatcataaaa cattaacaac
     2701 ttatttaaat acgttaatga aaacaggatt tgaaatatta gaaattattg aacctcaacc
     2761 agaagaaaaa ctgttagata caattcctga tatgaaagat gagctacgta gacctatgat
     2821 gttacttgta tctgcaaaaa aaagataagt aaatataaat aatcattatt gtagaaaaaa
     2881 aattgtagaa aataattaca ctaatggaga tgattatacc agtggtatta attacaccag
     2941 tagtaaggag gcaaaagcat tcgttgcttt tgccattttt taagttgcaa ttatacttct
     3001 acgtagtata tttcgtttcc attttcttct ataagctttt tcatatcttc aaattttaaa
     3061 aatacagtag cagtattatc atttggatgt atacctattt tatccatttt taataaatcc
     3121 ttatcaaata caacttttac aacagcctct ttatcattta atataccaaa aggagtcaca
     3181 gctcctttag taagtttcaa gtatttttga agtctttctt ctgatgcaaa actaagaggt
     3241 ttactatcaa tttgttgacg aatatctttt aaatctgctt ttttgtcttt acctaataca
     3301 actaaaaaat gttcttttcc tttagcatca cgaagaaata ggttttttac aacaaattcc
     3361 atatgtaatg tttttaattc ttccatttct tcaattgtat aaactggtgg atgatttaca
     3421 gcctcataag gtatgcttaa ctcatctaat tttttatata cttcctgttg ttgattgttc
     3481 atgatttcct cccattagaa atttatttta tatataaata atattatcac agaaaacttt
     3541 aaaagaaaac gttttatata atatagacaa tagattatat ttttataaag aagcaagaat
     3601 actcaataaa acttaaagaa attaaacaat ttctaaaaat accttgaaaa tagaacctta
     3661 tttgccattt ataaattata taaaaaggga ttatataaag tcatatatga aaaaactata
     3721 ttatactatc ttttcttttt ggaataaact atactttaaa tatagatatt taatttaaat
     3781 aaattttaca gtattaatag taaattatct tagaaaggaa tgtgctttat atgtctacag
     3841 acaaagttgt tggaatcata gatgaagaaa cggcagaact tgcaggaatt gaatatactg
     3901 gtaaaattta tgcttcttct ggtgttataa aacatataaa gaaaaaacat agatgtcaac
     3961 tgagtaagga tatttttaat gatataatag acactataaa aatggtatta aagtcacctg
     4021 aatatatagg aagtcatcct aaaaaacctg gaaaaagtgt ggagtttata aaaaaaattg
     4081 atgattatat tttagtagct acagaattag atacaaaaaa aggatattta tatgtatctt
     4141 caatgtatgc tataaaagaa gcaaaattag aaagtagagt aaacagtgga agagtaaaac
     4201 aatatgatgg ttaacataat attattaatt ttccccaaaa tattgaaaaa tattattata
     4261 taagttataa tattaatata cacgtagata tttattagtt agatttgagg ttggaaaagg
     4321 cacccaatac gctactatag agtagttaat agagatgcag gatacgccgc cctgccaaat
     4381 ctaattaaat taaaaagaga ggattaattc ctctcttttt gtttttttga gatactaatt
     4441 taatctatat ataaagattg aaggtcattt atactaaaag ttttcagtta tatacattaa
     4501 actaattaaa taagatattt ataatctata tatgatacat attatatatt a
//
LOCUS       DACTZW010000155         4508 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.158, whole genome shotgun sequence.
ACCESSION   DACTZW010000155 DACTZW010000000
VERSION     DACTZW010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4508
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.158"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(432..809)
                     /locus_tag="JAM15_18535"
     CDS             complement(432..809)
                     /locus_tag="JAM15_18535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HAT6800243.1"
                     /translation="MTISKIPQAELKVMKFIWEKNDTVTSKETIEAMERKYGWKQTTT
                     LTLLSRLVKKHFLSAEKIDRYTHYTIVVGHKEYLSVETKDFLSNIHDNSLQSLISALH
                     DDEVVDKDMLDLFESHFKNLEEE"
     gene            complement(996..1967)
                     /locus_tag="JAM15_18540"
     CDS             complement(996..1967)
                     /locus_tag="JAM15_18540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAT6800244.1"
                     /translation="MLLRASIGMGIVIFTMAFVQNVYQLLGLRILQGVFTGYATACTT
                     LIATQTDKNHSGWALGTLATASTTGSLIGPTVGGYIESILGLKSTFIITGGLLFVSFI
                     ISILFVVDNFKPKEIKESISIPKEQLNILPNKFLIASIFVTTFITQLALYSIEPIVTI
                     YISQLTNFASNVALIAGLTFSASGLANLLAAQKLGKMSDKIGPQKVLLISLLWAGIIF
                     IPQAFVKTAWQLMLLRFLLGLSVAGLNPSVNSLLKKIAPEEYVGKIFGYNASAQYIGC
                     SSGAFLGGQISAHLGIRTVFFSTSLLLFMNALWMYKFTGLFIKDKTK"
     gene            complement(2001..2198)
                     /locus_tag="JAM15_18545"
     CDS             complement(2001..2198)
                     /locus_tag="JAM15_18545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAT6800245.1"
                     /translation="MELWKRNLFVCWIGMFFSSIGMSQIAPILPLYIKQLGVTDVSLI
                     QQYSGIIFGCTFVVAAFFSPI"
     gene            complement(2266..3477)
                     /locus_tag="JAM15_18550"
     CDS             complement(2266..3477)
                     /locus_tag="JAM15_18550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HAT6800246.1"
                     /translation="MYSNEDYKFIEENAPCYIYDETNIIEKCKELKNNILGFDFLYSI
                     KTNPYNKIVKSIAEQGFGADASSTNEVMISSECGVSKDDIYYSSPGKTEIDIETVLDK
                     CIIIADSITEIELINKISKKHNQKVKIGIRINPDFTIDDDSAKSSKFGIDIEDMSSVF
                     KMLSMCDYVSVVGIHIHIKSQVLDFEKLGHYYEKCFFIALNLNKSKYINIEFINFGSG
                     LGVAYDNLRENPLNLKELSKLTQKIAFTNSNTLKSRLLIESGRFIVCKSGNYYVKIVD
                     IKVSRGKKYLIVKNGLNGFMRPIISNLIENITCGVELEGQEPLYTSNHAFSLSVLNNL
                     KEEEYVNVVGNLCTSLDVIANNVKLKKANIGDLISISNAGSYSYSLSPLLFSSYEFPK
                     QYYKRKDGYIE"
     gene            3758..4360
                     /locus_tag="JAM15_18555"
     CDS             3758..4360
                     /locus_tag="JAM15_18555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HAT6800247.1"
                     /translation="MEVCILMGSPKKKGNTAAILKPFIEELENYNSNIEVIWLYDCKI
                     EPCIACKKCQDNLFDFGCYCKDDVQKIFKKILMCDLIVFATPIYSWYCTSPMKALLDR
                     LVYGMNKYYGNEKGPALWAGKPVVLITTCGYRPEKGADIWENGMKRYCKHSQLKYIGM
                     LVERDLGKPNFMNKEKEKHSRQFAKQIYYILDNSIEVDNC"
BASE COUNT         1635 a          664 c          518 g         1691 t
ORIGIN      
        1 ataattattt aatattttta acaactttct atagtacatt ttaaaatatt tacagataag
       61 ttaccaataa tgaagtttaa aaatataaaa atcatttctt acttttagtt tacctataat
      121 aacaaaagac aggtttatgt tgtaataatt aaaaataata aaatatattt tgatatggtt
      181 aaatagaaat aatactttag attaatgaat attgacaagt tataaaatta ttttaaattt
      241 taaaaatcac ttcttattta aataagtggt atcatttaac ttgatactcc ctattccaat
      301 tattttaggc attttactaa ttagaaccta tttaatatta ctttatgaat agtgagtagc
      361 tgattaaata ataccattta tggttttcag ccatagatta attaaattct tagagttcta
      421 tcctgatata attactcttc ttctaaattt ttaaaatgac tttcaaataa atccaacata
      481 tctttatcaa caacttcatc atcatgtagt gctgaaatta aactctgtaa agaattgtcg
      541 tgtatattgc ttaaaaaatc ttttgtctca acacttaaat actccttatg tccaacaact
      601 attgtataat gagtgtatct atctattttt tctgcactta aaaaatgttt tttaacaagt
      661 cttgataaaa gtgtcaatgt agttgtttgt ttccaaccat attttcgttc catagcttca
      721 atagtttctt ttgatgttac tgtatcattt ttttcccaaa taaacttcat aacttttaat
      781 tctgcttgtg gtatttttga aattgtcata accttacgcc cctctcaaac ttttattaaa
      841 ttaatactat cgcaatatag tttttaagtc aaagattttg tcgataataa tattttccaa
      901 tttttaccat agggttattt tttatataat tctatgatag attacataaa aaatttttat
      961 tttacatcat aaaattagaa atgtaaatag tatgattatt tagtcttatc tttaataaac
     1021 aatccagtaa atttatacat ccaaagtgca ttcataaata acaataaact tgttgaaaaa
     1081 aatactgttc taatacctaa atgtgctgat atttgtcccc ctaaaaatgc tcctgatgaa
     1141 caacctatat actgggcaga tgcattatat ccaaatattt ttcccacata ttcttctggt
     1201 gcaatttttt taagcaagct gttaacagaa ggattaagcc ctgcaactga caaccctaat
     1261 aaaaatctca acaacatcag ttgccatgca gtttttacaa aagcttgtgg tataaatata
     1321 atcccagccc ataaaagtga aattaacaat actttttgag gacctatttt atccgacatt
     1381 tttccaagtt tttgagctgc taataaattt gctaatcctg atgcagaaaa tgtcaatcca
     1441 gctattaaag ctacatttga tgcaaagttt gtaagttgtg atatatatat ggttacaatt
     1501 ggttctatag agtataaagc tagttgagta atgaatgtgg ttacaaaaat agatgcaatt
     1561 aaaaatttat ttggcaatat atttaattgt tctttaggta tagaaattga ttcttttatt
     1621 tctttaggtt taaaattatc tactacaaat aaaatagaga tgataaatga tacaaacaac
     1681 aatcctcctg ttataataaa tgtactttta agacccaaga ttgattctat atatcctcct
     1741 actgttggac caattaatga gccagtagtt gatgcagttg caagagtacc caaagcccat
     1801 cctgaatgat ttttatctgt ctgtgttgca ataagagtag tacatgcagt agcataaccc
     1861 gtaaaaactc cttgaagtat tcttaatcct aataactgat aaacattttg aacaaacgcc
     1921 atggtaaata taactattcc catcccaata cttgcacgta aaagcattga ttttcttcca
     1981 tatttatcag cagctttccc tcaaattggc gaaaagaatg ctgctactac aaaggtacat
     2041 ccaaaaatta tacctgaata ctgttgtatt aaactaacat cagttacccc caactgttta
     2101 atatataatg gaagtatagg tgctatttgg ctcatcccta tagaactaaa aaacatacct
     2161 atccaacata caaataaatt tcttttccac aattccatat agaattacac cccctgcatt
     2221 ttaaattttt tcaataatac taagtttatt aatttatgct attgtttact caatatatcc
     2281 atcttttctt ttataatatt gtttgggaaa ttcataactc gaaaataata gtggtgataa
     2341 agaataggag taacttccag cattactaat tgaaatcaaa tctcctatat ttgctttttt
     2401 caatttaaca ttatttgcaa ttacatctaa tgatgtacag agattcccaa caacatttac
     2461 atactcttct tcttttaaat tatttaatac tgaaagagaa aaggcatgat ttgatgtata
     2521 taatggctct tgaccttcta attctactcc acaagtaata ttttcaatta aattagaaat
     2581 aataggtctc ataaatccat taagtccatt ttttacaata agatattttt tccctcttga
     2641 tactttaata tctacaattt taacataata attacctgat ttacaaacta tgaaacgtcc
     2701 tgattcaata agaagtcttg atttcagtgt gtttgaatta gtaaaagcaa tcttttgagt
     2761 taattttgaa agctctttaa gattaagtgg attttctcta agattatcat aagctactcc
     2821 aagtccacta ccaaaattta taaattcaat attaatatac ttacttttat ttaaatttaa
     2881 agctataaaa aaacattttt cataataatg tcctaacttt tcaaaatcca atacctgaga
     2941 tttaatatgt atatgaatcc caactacaga tacataatca cacatactta acatcttaaa
     3001 aacactgctc atatcttcta tatctatacc aaatttgctt gatttagcac tatcatcatc
     3061 tatagtaaaa tcaggattta ttcttattcc tattttaact ttctgattat gctttttaga
     3121 tatcttattt ataagttcta tttctgtaat actatctgca ataattatgc atttatctaa
     3181 aacagtttct atatcaatct ctgttttgcc tggtgatgaa taataaatat catctttaga
     3241 aactccacat tctgatgaaa tcataacttc attagttgaa gaagcatctg ctccaaaacc
     3301 ttgctctgca atgcttttta caattttgtt atatggattt gtttttatag aatataaaaa
     3361 atcaaaacct aaaatattat ttttcaattc cttacatttt tcaattatat tagtctcatc
     3421 atatatataa catggtgcat tttcttctat aaatttatag tcttcatttg agtacatatt
     3481 ttttacctcc aagattttaa atataatcat aaattaagca attataatcc tataagataa
     3541 ttttacaata aattaccata gttaactaca cacatatatg taaaaacata cctaaaatat
     3601 ttttaattat agatacattc caacttttat tgataaaaca atttgtttca attttattac
     3661 aaatatacaa agtgtattgt tgttaacgta ttctcatagt atcctaaaac tatattaagc
     3721 actaaaaact attttaaaat actgtggagg tatcaatatg gaagtatgca ttcttatggg
     3781 aagtcctaag aaaaaaggta atactgctgc tattttaaaa ccttttattg aggaattaga
     3841 aaattataat tcaaatattg aagtaatatg gttatatgat tgtaaaatag agccatgtat
     3901 tgcttgtaaa aaatgtcagg ataacttatt tgattttgga tgttattgta aagatgatgt
     3961 tcagaaaatt ttcaagaaaa ttcttatgtg tgatttaatt gtttttgcta ctccaattta
     4021 ttcttggtac tgcacttctc caatgaaagc actacttgac agattggtgt atggaatgaa
     4081 taagtactat ggtaatgaga aaggccccgc tctatgggca ggaaaaccag tagtacttat
     4141 tacaacatgt ggatatagac ctgaaaaggg tgctgatatt tgggaaaatg gtatgaagcg
     4201 ctactgtaag cattcacagt taaaatatat aggaatgctt gttgaacgtg atttaggtaa
     4261 acctaatttt atgaataaag aaaaagaaaa acattctcgt caatttgcaa aacaaattta
     4321 ttatatttta gataattcaa ttgaagtaga taactgctaa agacataata ctccaagtaa
     4381 agtattgata atataaataa atcttacata atttgcttat ttaaaataag atatatattc
     4441 ttctaaaaag taacaataat taaaatattt tttatcattt caacaatgat aaagaggctt
     4501 atatctat
//
LOCUS       DACTZW010000156         4463 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.159, whole genome shotgun sequence.
ACCESSION   DACTZW010000156 DACTZW010000000
VERSION     DACTZW010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4463
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.159"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            156..803
                     /locus_tag="JAM15_18560"
     CDS             156..803
                     /locus_tag="JAM15_18560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6800248.1"
                     /translation="MNILIADDEISMLKILCAYFKKENFNVFTAKNGEEALDIFYENK
                     IDLAILDWMMPIIDGIEVCKEIKENSNTKVLMLTAKSQSEDEIEALNIGADEYIKKPF
                     DPRVLIIRAKKLINYKNTINIKDLKIDFGSSKVFKGDKELLLTKKELELIRCLINNKG
                     MVLSREKLLDLVWGLDYEGDFRTVDTHIRRLRVKIGEDIIKTYRGLGYSLEDFND"
     gene            796..2190
                     /locus_tag="JAM15_18565"
     CDS             796..2190
                     /locus_tag="JAM15_18565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAT6800249.1"
                     /translation="MTKLNKKLSISISIVVVVVYIISIIINSMFIHRYYLHEKRNILD
                     NVENEIKDKDIDKLKSDITLIEEKNNIDIVYIELDKNHKDKGNIDKINQDLLNAFWKK
                     GLSLNKFWIEENSLNNIDKKSINKIYNQGKTKYSLLVKFIKKDNYLFAISIPIEHSEE
                     TIGIVNRFNIIMGIFSVVIITILTFILSNRVIKPMERLKFLSKDISELNFRTEDIKTN
                     DEIEELAYSINIMSEKLEKAHNELNKRNENLKTFISDASHEMKTPIALIKAYAIGMKD
                     GLDDGTYTDTIIEQAENMTNTINSLLYWAKYEKKERSLCLVDLKERLYKSLKNYELLI
                     ERGSISVKCSVDDKELIISSDKDSIDMVFNNLISNAIKYTNNNEIEINLFEENERIIL
                     SIKNGIDYNMGDDIENMWKPFYVLEKSRSKELSGTGLGLTIVRTILEENNFRYRVEIC
                     DGIIEFYIIFIKVI"
     gene            2615..>4463
                     /locus_tag="JAM15_18570"
     CDS             2615..>4463
                     /locus_tag="JAM15_18570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HAT6800250.1"
                     /translation="MKIPKKIAAMLTVTMIAGSSTAGIASAQTVATNLTGQERYETAV
                     KISQDGWKNADEVVIVNDSSIADALSATPFAKAKNAPILLTSKDKLNDKTKAEIQRLK
                     AKKVYLIGGTSVLSTNIEKEIKDLKISFERISGAERYQTSLELAKKLDAISDVKKIAV
                     VNGEKGLADAVSVGAPAAQNNMPVILADSKNGTAVADKFIKDAGITQSYVVGGESSIS
                     EAVKNKLPNSTRLGGTDRNDTNAKVIKEFYKKTDLKNAYVTKDGMNKQDQLIDALAVG
                     VLGAKNQSPVVLVGKNLSASQKSLVNSKSFDKITKVGGNGNETAFNEMKSLQEVKTVE
                     AKTISELKSAIDKATANDVINFKPTSEVKEAFTIQTDKAITVNLNGTYTKTVTINMPN
                     GDVNNYAKVDDVVIDDVKDGTFVNYGKITNLKVNDKNGAKIENNSKGEIGSLTVASGA
                     SQVKVTNDGKITTVTNNSKGTTIDNKGTISSVKGDNSPTISGNSPSSNSSGGSSSSGG
                     SSHGGGSSSSKVDKVVLKNTITAANKLYNEAIEGTNVGEYKVGSKAIYKTAIDKAQAI
                     LDKSGVTQKEVNDAVTALNTATDTFKAGKVVAVDKTALQDAVTAATALHA"
BASE COUNT         1946 a          433 c          777 g         1307 t
ORIGIN      
        1 atataatcga gatattgtta agacattgtc gagatattat aatatataac taatgtatta
       61 taaatagttg taaacttcct gtaacatata ttttatataa ttaaagtaat ggatataata
      121 tgaaatataa taatgaattt tagggatgtg aataaatgaa catattaatt gctgatgatg
      181 aaattagtat gcttaagata ctttgtgcat attttaaaaa agaaaacttc aatgtgttta
      241 ctgcaaaaaa tggggaagag gctttagata ttttttatga aaataagata gacttagcta
      301 tattagactg gatgatgcca ataattgatg gaatagaggt ttgtaaagag ataaaggaaa
      361 atagtaatac aaaggtactt atgttgactg ccaaaagtca aagtgaagat gaaatagaag
      421 cactcaacat tggagcagat gaatatataa aaaaaccatt tgatcctaga gttttaataa
      481 taagagctaa gaaactaata aattataaaa atacaattaa tattaaagat ttaaaaatag
      541 attttgggtc aagtaaagtt tttaaaggtg ataaggaatt attattgact aagaaagaat
      601 tagaattaat tcgttgttta atcaataata aaggaatggt tttatctagg gaaaaacttt
      661 tagatttagt atggggattg gattatgagg gagattttag aacagtagat actcatataa
      721 gaagattaag ggtaaaaata ggagaagata taataaaaac ttatagagga ttagggtata
      781 gtctggagga ttttaatgac taaactaaac aaaaaattgt ccataagtat atctatagta
      841 gttgtagttg tttatataat atctataatt ataaatagta tgtttattca tagatattat
      901 ttacatgaaa aaagaaatat attggataat gttgaaaatg aaattaaaga taaagacata
      961 gataaattaa aatcagacat tactttaatt gaagaaaaaa ataatataga tatcgtatat
     1021 atagaattag ataaaaatca taaagataaa ggtaatatag ataaaataaa tcaagattta
     1081 ttaaatgcat tttggaaaaa aggtttaagt ttaaataagt tttggattga agaaaatagt
     1141 ttaaataata ttgataagaa aagtataaat aagatataca atcaaggtaa aacaaaatat
     1201 agtttgcttg taaaatttat caagaaggat aattatttgt ttgctatatc tatacctata
     1261 gaacattctg aagaaactat tggcattgta aatagattta atataataat gggaattttt
     1321 tcagtagtta taataactat acttacattt atattatcaa acagagttat aaaacctatg
     1381 gaaaggttaa agtttttatc taaagatata tctgaattaa attttaggac tgaagatata
     1441 aaaacgaacg atgaaataga agagctagct tacagcataa acataatgag cgaaaaactt
     1501 gaaaaagcac ataatgaatt gaataaaaga aatgagaatc taaaaacttt tatatcagat
     1561 gcatctcatg aaatgaaaac tccaatagca cttataaaag catatgcaat aggtatgaaa
     1621 gatggtttgg atgatgggac ttatacagat acaataattg aacaagcaga aaatatgacc
     1681 aatacaataa attctctttt atattgggca aaatatgaga agaaggagag aagtctgtgt
     1741 ctggtagatt taaaggaaag gttatataaa agtttaaaaa actatgagct gttgatagaa
     1801 agaggtagta taagtgttaa atgcagtgta gatgataaag aacttataat aagttcggat
     1861 aaagatagta tagatatggt atttaataat ttgattagta atgctataaa gtatactaat
     1921 aataatgaaa tagagattaa tctttttgaa gagaatgaga gaattatatt atccataaaa
     1981 aatggtatag attacaatat gggagatgat atagaaaata tgtggaagcc tttttatgtt
     2041 ttagagaagt cgagaagtaa ggagctttct ggtactggtc ttggtcttac catagttaga
     2101 actatacttg aagaaaataa ttttagatac agggttgaaa tttgcgatgg aattatagaa
     2161 ttttatatta tctttataaa agtaatttga attaaaatgt aaatataaag aataattaaa
     2221 aaaatatcgc aattatttgt ttttcatatg gataaaattg gttatttaat atataattac
     2281 aagtataaat aataaaattt atttgtaaaa agagtagcac ttttaattct aaaggctact
     2341 ttttttatac aaaaccatgt tttttataac aattcattaa cataaaaatc aaacttacct
     2401 taaaatataa atttacaaat ttttcaatca ataagaaaat ttctctattc cttacataat
     2461 gactgtaatg taacaaaata attacaaatt aattatgaaa tcattatagt tagaaacctc
     2521 tttaaaatta gatattaagt atcctttaga attagaacgg gaacaaagtt aaaaaattaa
     2581 gtaatatcaa atggacaagg gggaagaaaa taaaatgaaa ataccaaaga agattgctgc
     2641 aatgcttaca gttacaatga tagctggaag ttcaacagca ggcatagcta gtgcacaaac
     2701 tgtggcaaca aatttaacag ggcaagaaag atatgaaact gctgttaaaa taagtcaaga
     2761 tggatggaaa aatgctgatg aggtagtaat cgtaaacgac tcatctatag cagatgctct
     2821 atctgcaaca ccatttgcaa aagcaaaaaa tgctccaata cttttaacaa gtaaagataa
     2881 attaaatgat aagacgaaag cagaaataca aagattaaaa gctaaaaaag tatacttaat
     2941 aggtggaact tctgtattaa gtacaaatat agaaaaagaa ataaaagatt taaaaatatc
     3001 ttttgagaga atctctggag ctgagagata tcaaacatcc ttagaattag caaagaaatt
     3061 agatgctata agtgatgtta agaaaatagc tgtagttaat ggtgaaaaag gacttgcaga
     3121 tgctgtaagt gtaggagcac cagctgcaca aaacaatatg ccagtaatac ttgctgattc
     3181 taaaaatgga acagcagttg cagacaaatt tataaaagat gctggaataa ctcaatctta
     3241 tgtagtaggt ggagagagtt caatttctga agctgttaaa aataaactac caaatagtac
     3301 aagactaggt ggaacagata gaaatgatac aaatgcaaaa gtaataaaag aattttataa
     3361 aaagacagat ttaaaaaatg cttatgtaac taaagatggt atgaataaac aagaccaact
     3421 tatagatgca ctagcagtag gtgtattagg tgctaaaaat caatcaccag tagttttagt
     3481 tggaaagaac ttatcagctt cacaaaaatc tctagttaac tctaagagtt ttgataagat
     3541 aactaaagtt ggtgggaatg gtaatgagac agcatttaat gaaatgaagt cattacaaga
     3601 agtaaaaaca gttgaagcta aaacaatttc tgaattaaaa tcagctatag ataaagctac
     3661 tgctaatgat gttataaact ttaagccaac tagtgaggtt aaagaagcat ttacaataca
     3721 aactgataag gcgataacag taaacttaaa tggtacatat acaaagactg tgactatcaa
     3781 catgcctaat ggtgatgtaa ataactatgc aaaagtggat gatgtagtta tagatgatgt
     3841 aaaagatgga acttttgtta actacggaaa aataactaac ttaaaggtta atgataaaaa
     3901 tggagccaag atagaaaata attctaaagg tgagattggt agtttaacag tagcatctgg
     3961 agcaagtcaa gtaaaagtga ctaatgacgg gaagataact acagttacaa ataattctaa
     4021 aggaactact atagataata aaggtacaat aagtagtgtt aagggagata attctccaac
     4081 aataagtgga aatagtccaa gttctaactc atcaggagga agttcatcaa gtggaggctc
     4141 ttcacatgga ggaggaagtt cttcatcaaa agtagataaa gtagttttga aaaatacaat
     4201 aacagcagca aataaattgt ataatgaagc aatagaggga acaaatgtag gtgaatataa
     4261 agtagggtca aaagcaatat ataaaacagc aatagacaaa gcacaggcaa tattagacaa
     4321 atctggtgta acacaaaaag aagtaaatga tgcagtaaca gcattaaaca cagcaacaga
     4381 cacatttaaa gcaggaaaag tagtagcagt agataaaaca gcattacaag atgcagtaac
     4441 agcagcaaca gcattacatg cta
//
LOCUS       DACTZW010000157         4386 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.160, whole genome shotgun sequence.
ACCESSION   DACTZW010000157 DACTZW010000000
VERSION     DACTZW010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4386
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.160"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(68..274)
                     /locus_tag="JAM15_18575"
     CDS             complement(68..274)
                     /locus_tag="JAM15_18575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012100274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800251.1"
                     /translation="MSKYSSLWEYVKKNNSQSFKLTFEEIKDIAGIEIDHSFLKYKKE
                     LNEYGYQVGKISLKEKTVIFDKIS"
     gene            complement(677..1072)
                     /locus_tag="JAM15_18580"
     CDS             complement(677..1072)
                     /locus_tag="JAM15_18580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5-phosphate oxidase"
                     /protein_id="HAT6800252.1"
                     /translation="MKALEFLNKAGVYYLATVDENNQAHVRPLGFVMEYNGKLTFCTS
                     NQKDMFKQLIFNPKVELCCIDQNLNTLRILGEAVFVTSKETQAKALEIMPSLGQMYSV
                     GDGKFEIFSIDKAKVSCCSMSGKKIDVEL"
     gene            1213..1605
                     /locus_tag="JAM15_18585"
     CDS             1213..1605
                     /locus_tag="JAM15_18585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6800253.1"
                     /translation="MSINTEKNITKNVEELTCPIRYALDIVGGKWKLPIICMLAVENP
                     IRYSSIKRKLDGITNTMLAQSLKDLESTGIVHRKQYNEIPPKVEYTLTSKGKSIVPIL
                     QQFANWGATNMQEKNTCGLSCKECRKIK"
     gene            complement(1699..2115)
                     /locus_tag="JAM15_18590"
     CDS             complement(1699..2115)
                     /locus_tag="JAM15_18590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HAT6800254.1"
                     /translation="MNWQDAFFQDTKPTFEQINEFINNPLWDKLNKTLVSTYNVEPKL
                     EYSKCSMQRGWNVKYKKRGKSLCTLYPQEGYFKALVIVSESNRVEVDLFINTCCDYIK
                     KIYNEVNFFNGSKWLMIQVDSLLVLNDMLELIKFRA"
     gene            complement(2130..3041)
                     /locus_tag="JAM15_18595"
     CDS             complement(2130..3041)
                     /locus_tag="JAM15_18595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAT6800255.1"
                     /translation="MHAWESIQITLDLIEANLSEEISINELANKANLSPFYYQRLFKR
                     LVNKTVMEYIKLRRLARASEYLAEHKNRILDVALNFGFASHETFTRSFKKAYGLTPEK
                     YRANPVKLNHFIKPELILNYAMVDEGVPLIADDIVIEVNRKTLSNPRTFVGIEIEVPI
                     CQLVGGETTGIAIVEELWMKLGSQRHNIPNQIPGGNEFAALYMGNAKEGNCMYMAGVE
                     VESGTSVEGYNTFELPAKEYLVCGFEAENFNELVNSAVFKADKFMERWMKKHNLTTTD
                     FAIEMYYPTTPEAAYLEHWIVPVPIEQ"
     gene            complement(3228..4250)
                     /gene="splB"
                     /locus_tag="JAM15_18600"
     CDS             complement(3228..4250)
                     /gene="splB"
                     /locus_tag="JAM15_18600"
                     /EC_number="4.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002580203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore photoproduct lyase"
                     /protein_id="HAT6800256.1"
                     /translation="MFNPKGIIFEKGTLDTDVGKKIYNKFRDNKDVEIINISSNRIKE
                     HIPGENLYEQYRSGKQTMVVGIRKSLKFQTCKPSANYQLPLVSGCMGRCEYCYLNTQL
                     GDKPFIRVFVNVDEILEQTKKYIEDRKPQVTIFEGAATSDPVPVEPYTNSLKKTIEFF
                     GREEKGRFRFVTKYSDVDSLLDAEHNNHTEIRFSINTPRIINEHEHYTASANKRIESA
                     VKLARAGYQIGFIIAPVFLYEGWKEEYKNLIISIKEALPKDFDKKIIFEVISHRYTTK
                     AKNRILEIYPDTLLPMENEDRKFRYGQFGYGKYVYDKEQLDDMKEFFLKEINGVFKNS
                     LIKYII"
BASE COUNT         1478 a          738 c          465 g         1705 t
ORIGIN      
        1 ctacgccctt ttttatttat aataatcatc aatacaaatt attttattat atgtaattat
       61 ttatgtctta actaatttta tcgaaaataa cagtcttctc ttttaaagag atttttccta
      121 cttgatatcc atattcattt aattcctttt tatatttcaa aaacgaatgg tctatctcta
      181 tcccagcaat atcttttatt tcttcaaaag ttaatttaaa cgattgacta ttgtttttct
      241 taacatattc ccataaagaa ctatatttac tcatcttata tcactccttt taaaatcata
      301 tcttatctat taatttatat tctatcatta ttaatgtata aagtcatgct acttattatt
      361 tatatacaaa aatatccaaa taataagtag caatttttta tagtcataat atttttttca
      421 gattaaataa aaatcaatta tagttaaaat attttttaaa agaaatctat cccattataa
      481 agtaaatttt aattatctta tttctagtat gtaattattc aaaatagtat atcattattg
      541 aaatacacat ctaataacta aaaattttta catattcatt atttaaaaat ctttttattg
      601 cacttaaatt aaatctatca atatttcagt aataacgttt tcttaatttt cactatggat
      661 gtcgattcaa ttataattaa agctctacat caatcttttt accactcatt gaacaacaac
      721 taacttttgc cttatcaata gagaatattt caaacttacc atctcctaca gagtacatct
      781 gacctaaact tggcattatt tcaagtgcct tagcttgtgt ttcttttgat gtaacaaata
      841 ctgcttcacc taaaatacgt agagtattaa ggttttggtc tatacaacaa agttcaacct
      901 ttggattaaa aataagttgc ttaaacatat ccttttgatt agatgtgcaa aatgtaagtt
      961 taccattgta ttccataaca aatcctaaag gacgcacatg tgcttgattg ttctcatcaa
     1021 ctgttgctaa ataataaact cctgccttgt tcaaaaattc taatgctttc ataattctta
     1081 cacccctttt aaatacttgt attaaggatt atcctttgat ataattttaa tataaaatac
     1141 agaaaaaaca agtatgcagt tttttctgat aaagtataaa aaagatacta ctataactaa
     1201 ggagtaatta aaatgagtat aaatactgaa aaaaatataa ctaaaaacgt tgaagaatta
     1261 acctgtccaa tccgttatgc attagacatt gtcggtggta agtggaaatt acctattata
     1321 tgtatgttag cagttgaaaa tccaattaga tatagtagca taaaaagaaa attggatggc
     1381 attacaaata ctatgctagc tcaatcatta aaagatttag agtctactgg tattgttcat
     1441 cgtaaacaat ataatgaaat tcctccaaaa gttgagtata cattaacaag taaaggtaaa
     1501 agtattgtgc ctattttaca acaatttgct aattggggtg ctactaatat gcaagaaaaa
     1561 aacacatgtg gacttagttg caaagaatgt agaaagataa agtaaattta ctaaattatt
     1621 catattatag actatatatt aatttatctg attgaatata aaaacaggat gacttatata
     1681 ttcatcctgt tctatatgtt aagctctaaa tttaattagt tcaagcatat cgtttaatac
     1741 caataaacta tctacttgaa tcattagcca tttacttcca ttaaaaaagt ttacctcatt
     1801 atatattttt ttgatataat cacaacaagt attaataaat aaatcaacct ctactctatt
     1861 gctttcactt acaataacca aagctttaaa ataaccttct tgtggatata aagtacatag
     1921 tgatttacct ctttttttat attttacatt ccaacctctt tgcattgaac atttactgta
     1981 ttcaagctta ggttctacat tataagtaga aaccaaagtt ttatttaact tgtcccataa
     2041 tggattatta ataaattcat taatttgctc aaatgtaggt ttagtatctt gaaaaaacgc
     2101 atcttgccaa ttcatattca tcatcctttc tattgttcaa taggaaccgg aacaatccaa
     2161 tgttccagat atgctgcttc aggtgtagtg gggtaataca tctcaattgc aaaatcagta
     2221 gttgttaaat tatgtttctt catccatctt tccataaatt tatctgcttt aaaaacagct
     2281 gaattaacta actcattaaa gttttctgcc tcaaatccac atactaaata ttctttagct
     2341 ggcaactcaa aagtattata tccttctact gatgtacctg actctacctc tacacctgcc
     2401 atatacatac aatttccttc ttttgcattt cccatataaa gagcagcaaa ttcatttcca
     2461 cctggaattt gatttggtat attatgtctt tgacttccaa gtttcatcca taattcctct
     2521 actattgcaa ttccagttgt ttcaccaccc accaactggc aaataggtac ttctatttct
     2581 attccaacaa atgtccttgg attactcaat gtcttacgat tgacttcaat cactatatca
     2641 tctgcaatca gtggaacacc ttcatcaacc atagcataat ttaaaattaa ttctggctta
     2701 ataaagtgat tgagttttac tggatttgct ctatattttt ctggagttaa tccatatgct
     2761 tttttaaagg aacgtgtaaa tgtctcatga ctagcaaatc caaaatttaa agctacatca
     2821 agtatacgat tcttatgttc tgctaagtat tcagaagctc ttgcaagacg acgaagcttt
     2881 atatactcca ttacagtctt atttaccaat cttttaaata gtctttgata gtaaaatggt
     2941 gataaatttg ctttatttgc taattcatta attgatattt cttctgataa atttgcttct
     3001 attaaatcca atgtaatttg aatagactcc catgcatgca tactataact cctcctgata
     3061 tttttgttac tcttaccctt tatagtatca aaactagaaa aaatgttctt gatagatagt
     3121 gcccttttta attttcttat atgatagtgc taaatctcat ctcattgctt tattataaac
     3181 ataaaatata taaaaataaa atatagcaaa tctttaggta agatttgcta tattatatat
     3241 tttattaaac tatttttaaa tactccattt atttccttaa gaaagaactc tttcatatca
     3301 tctaattgtt ctttatcata cacgtactta ccatatccaa attgaccgta tctaaacttt
     3361 ctatcctcat tttccattgg caatagtgta tctggataaa tctctagtat tctatttttt
     3421 gctttagttg tatatctatg agatataact tcaaatataa tttttttatc aaaatccttt
     3481 ggtaaagctt cttttatact tataatcaaa tttttatact cttctttcca accttcatat
     3541 aaaaacacag gtgctattat gaaaccaatc tgataaccag ccctagcaag ttttacagct
     3601 gactctattc ttttatttgc agaggctgta taatgctcat gttcatttat aattctagga
     3661 gtattgatac taaatcgtat ttctgtatga ttattatgtt cagcatccaa taagctatcc
     3721 acatcactgt atttagtaac aaatctaaat cttccttttt cctctcttcc aaaaaactct
     3781 attgttttct tcaaagaatt ggtatatggc tctactggaa ctgggtctga tgtagctgcc
     3841 ccttcaaata tggttacctg tggctttcta tcttcaatat atttttttgt ctgttcaagt
     3901 atttcatcta catttacaaa cacccttata aatggtttat cacctaattg tgtgttcaaa
     3961 taacaatact cacatcttcc catacatcca ctgacaagtg gtagttgata attagcagaa
     4021 ggtttacatg tttgaaactt cagacttttt ctaatcccaa ctaccatagt ctgcttccca
     4081 cttctatatt gttcatatag attttcacct ggaatgtgtt ctttaatcct atttgatgat
     4141 atattaatta tctctacatc tttattatct ctaaatttat tgtatatttt tttgcccaca
     4201 tcagtgtcta aagttccttt ttcgaatatt attcctttgg gattaaacat ttatttcacc
     4261 tctacttaaa gtttttaaat cgaagaattt tataaaatat tacttaatta atcttccctt
     4321 ttttaaactc ctttatttat tagaaagtaa aataaaagct taagacaagt ttattatata
     4381 tataac
//
LOCUS       DACTZW010000158         4038 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.161, whole genome shotgun sequence.
ACCESSION   DACTZW010000158 DACTZW010000000
VERSION     DACTZW010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4038
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.161"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            70..468
                     /locus_tag="JAM15_18605"
     CDS             70..468
                     /locus_tag="JAM15_18605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAT6800257.1"
                     /translation="MIKKIEHVVITNNNIENYINFYKKFGFSSKEMSEKYKLKARNVK
                     INLNIKGYKFLPYVKNLKASRDNLCFKINTNIDEPKKYLEQNEIQIKRGIVECTGVFG
                     NMKSIYLKKTNGNLIELSNHRITESKPWKI"
     gene            456..1394
                     /locus_tag="JAM15_18610"
     CDS             456..1394
                     /locus_tag="JAM15_18610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HAT6800258.1"
                     /translation="MENLILSINVVLPLFLTMSLGYVLKKLGLFDTHTLNKMNNVCFK
                     SFLPLLLFFNIYNTDLDGSLNFKLMAVAVIIIFSIFLILVFIIPKIEKDNKTRGALIQ
                     GVFRSNFVIFGIPVTISLFGDKSIGVTSLLIAVIVPMFNVLSVVILEIFRGGKVNIRH
                     MIKSVLTNPLIIASFIGLTMLILNINIPTFLHKTIGDISKIATPLSLIILGGSFSFSA
                     IKGHIKPIILGVCGKLILVPSIFLPISIFLGFRNVELTSLMIMLSAPTAVSSFTMAQQ
                     MDSDSELAGQIVVFTSGFSIITVFLIIFILKQNNLI"
     gene            complement(1777..2001)
                     /gene="secG"
                     /locus_tag="JAM15_18615"
     CDS             complement(1777..2001)
                     /gene="secG"
                     /locus_tag="JAM15_18615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HAT6800259.1"
                     /translation="MSNILMGVQVVLGILLVISIMPQDSKNALPSEFGGEGSQAYFKP
                     KGKQAFLARVTKITAVLFFINALALLIVKK"
     gene            complement(2594..3886)
                     /gene="eno"
                     /locus_tag="JAM15_18620"
     CDS             complement(2594..3886)
                     /gene="eno"
                     /locus_tag="JAM15_18620"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HAT6800260.1"
                     /translation="MSVIELVYAREVLDSRGNPTVEVEVVLEDGAMGRAIVPSGASTG
                     AFEAVELRDGDKGRYLGKGVETAVANVNEIIAPEIEGMDAFDQPAIDAIMIELDGTPN
                     KGKLGANAILGVSMAVARAAADEIGLPLFQYLGGVNAKQLPVPMMNILNGGEHADNNV
                     DVQEFMILPVGACCFKEGLRMGAEVFHSLKKVLGEKGLACGVGDEGGFAPNLGSNREA
                     LELIVEAITKAGYKPGEDVMLGLDVAATEMYNKETKKYVLAGEGKELTAAEMVALYED
                     WSNNFPIITIEDGLDEEDWDGWKLLTEKLGNKLQLVGDDLFVTNTERLEKGIENGVAN
                     SILVKVNQIGTITETLDAIEMAKRAGYTAVISHRSGETEDSTIADLAVAVNAGQIKTG
                     APSRTDRVAKYNQLLRIEEMVGEQARYCGLKSFYNLKK"
BASE COUNT         1387 a          649 c          459 g         1543 t
ORIGIN      
        1 atcaacctat ataaaattta ataacttata taaatttaac taatttatat aaaatcttaa
       61 ggagttgcca tgataaaaaa aatagagcat gtggtcatta ctaataataa tatagaaaat
      121 tatatcaatt tttataaaaa atttggtttt tcatctaaag aaatgagcga aaagtataaa
      181 cttaaggcta gaaatgttaa gataaatctt aacataaaag gttataaatt tttaccttat
      241 gttaaaaatt taaaagcaag tagagataac ttatgtttta aaataaacac aaatattgat
      301 gagccaaaaa aatacttaga acaaaatgag attcaaatta agcgaggaat tgtagaatgt
      361 acaggtgtct ttggtaatat gaaatctatt tatttgaaaa aaactaatgg aaatttaatt
      421 gaattatcaa atcatagaat cacggagagt aaaccttgga aaatttaatc ctatcaataa
      481 atgttgttct tcctttgttt ctcacaatgt cacttggata tgttctaaaa aaattaggtc
      541 tatttgatac tcatacttta aataaaatga ataatgtctg cttcaagtct ttcttgccat
      601 tattattatt ttttaatata tacaatacag atttagatgg ttctcttaat tttaagctta
      661 tggctgtagc tgttataatt attttttcaa tcttcttaat cttagtcttt attattccta
      721 aaattgaaaa agataataag acaaggggtg cattaataca aggtgtattt cgtagcaatt
      781 tcgttatatt tggtattcct gtgacaattt cactatttgg cgataagagt attggagtca
      841 catctttatt aattgcagtt attgtaccta tgtttaatgt attatctgtt gtaattcttg
      901 aaatttttag aggtggcaaa gtaaatataa gacatatgat taaaagcgtc ttaacaaatc
      961 cactcataat cgcctctttt ataggattga caatgctaat tttaaatatt aatataccta
     1021 catttttaca caaaactatt ggtgatattt ctaaaatagc tactccttta tcacttataa
     1081 ttctaggcgg ctcttttagt ttttctgcta taaaggggca tataaaaccc attatattgg
     1141 gcgtatgtgg aaaacttata cttgtacctt ctatattttt accaattagc atttttcttg
     1201 gatttagaaa tgtagaatta acttcactta tgataatgtt atctgctcca actgcagttt
     1261 cttcatttac aatggcacaa cagatggatt ctgacagtga attagctgga caaattgtag
     1321 tatttacttc tggattttct ataattacag tatttttaat aatatttatt ttaaagcaga
     1381 ataatcttat ttaatgatat ttgataacac aaattggtat tatgagaaac atatataaaa
     1441 ttgatttaat tgcgtaaaaa catattatta tactattttt actatataat ataactttgt
     1501 gtatattatc tcgttaaaca tggtgaaagt agtgttgcta tatatttttt agtttgaaaa
     1561 aatatataaa tacaaacaat atataaatac aaataataaa tgccaacaaa tagtcaatct
     1621 ataaaataaa aactggacta atcatataaa atcattagtc cagcttttat tttacgtact
     1681 ttttatgttg atgtactttt attaaaaact aaatttaatt tttaaatatc tagcaaatgc
     1741 actaattaaa taatggccag ttattcaaca atatcactac ttcttaacta taagtaatgc
     1801 caatgcattt ataaaaaata atactgctgt tatctttgta actctagcaa gaaatgcttg
     1861 ttttcctttt ggtttaaagt aagcttgact tccttctcca ccaaattctg aaggtaaagc
     1921 attcttagaa tcttgaggca ttatgctaat tactagtaaa atccctagta ctacttgcac
     1981 acccattaaa atgttgctca ttcttgcccc tcctatctgt ttattactta aatttcatta
     2041 ctctttagtg tatcacaata atatagccat ttcaagacta ttatgctata aataacatac
     2101 aaaaaaatat attgttacta taatatatta ctatattctc aatataaaaa tgaataaaac
     2161 ttagaagaga aaactattta aattaatgca taaattaaca cttaaaataa tctactctca
     2221 ttgcatatat tataaatagc caccaaaata aaacaatcat tttaaaatat tgatataact
     2281 tttaatttca acataattta aaataaataa cccacattta gcaatgatac tttaatgaca
     2341 attatgatta aatcaaaata tgtcttcact tttatttttt aataaaaacc tcctatgcaa
     2401 ttagataaaa atgagataga aatatttatt catatttttt ctgaatctat gaataaaatt
     2461 aagtaataaa atataaaaaa ggataagtgc cttgaaaaat caattaacac ttatctcttt
     2521 tatatcttat aagatgagct taaatatctt atattctctc ttcattaatc ttttttagta
     2581 actattttaa taactatttt tttaagttat agaaagattt taatccacaa tatctagctt
     2641 gctctccaac catttcttct attcttaata attggttgta cttagcaact ctatcagttc
     2701 ttgatggagc accagttttt atttgaccag catttactgc aacagctaaa tctgctatag
     2761 tagaatcttc agtttctcct gatctgtgag atataacagc agtatatcct gctctcttag
     2821 ccatttctat agcatctaaa gtttcagtta ttgtacctat ttgattaact ttaactaata
     2881 tagagttagc tactccattt tcaattcctt tttctaatct ctctgtgtta gtaacaaata
     2941 agtcgtcacc aactaattgt aatttatttc ctaatttttc agttaataac ttccatccat
     3001 cccaatcttc ttcgtctaaa ccatcttcta tagttattat tgggaagttg tttgaccaat
     3061 cttcatataa agcaaccatt tcagcagcag ttaactcttt tccttctcct gctaaaacgt
     3121 attttttagt ttctttgttg tacatttctg tagcagcaac gtcaagacct aacataacgt
     3181 cttcacctgg cttatatcca gcttttgtta tagcttcaac tattaattct aaagcttctc
     3241 tgtttgaacc taagtttgga gcaaatccac cttcgtcacc tacaccacaa gctaatcctt
     3301 tttctcctaa aactttcttt aatgaatgga atacttctgc tcccattctt aaaccttctt
     3361 tgaaacaaca agctcctact ggtaatatca taaattcttg aacatcaacg ttattatcag
     3421 catgctctcc accgtttaat atgttcatca ttggaacagg taattgttta gcatttactc
     3481 cacctaaata ttggaataat ggtaaaccta tttcatcagc agctgctcta gctactgcca
     3541 ttgaaacacc taatatagca ttagctccta atttaccttt gtttggagtt ccatctaatt
     3601 ctatcatgat tgcatctata gctggttggt caaatgcatc cattccttct atttcaggtg
     3661 ctattatttc atttacgtta gcaacagctg tttctacacc ttttcctaag tatcttccct
     3721 tatctccatc tcttaattca acagcttcaa aagctcctgt agatgctcct gatggaacta
     3781 ttgctcttcc cattgctcca tcttctaata ctacttcaac ttctacagtt ggatttcctc
     3841 ttgagtctaa tacttctcta gcatatacta attcaataac tgacatttgt atatctccct
     3901 tcgattttct attagttaaa ttttcattta ctgtaaacat ccgtctacta ttttaatcta
     3961 ctttctatat tatagtacat aaagttgctt ttgaaaatta ggtacaaatt tatttgatgg
     4021 gtaaatttgt aaaagttc
//
LOCUS       DACTZW010000159         3944 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.162, whole genome shotgun sequence.
ACCESSION   DACTZW010000159 DACTZW010000000
VERSION     DACTZW010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3944
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.162"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(130..1422)
                     /gene="brnQ"
                     /locus_tag="JAM15_18625"
     CDS             complement(130..1422)
                     /gene="brnQ"
                     /locus_tag="JAM15_18625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HAT6800261.1"
                     /translation="MGEKQINFKDVIVIGFALFAMFFGAGNLIFPPYLGVLSGSSWLI
                     AFIGFLFADGGLALLAVIAATKFNGDTSKMFSRAGKGLSIALGCAMVICIGPLLAIPR
                     TAATTYEMGILPTIGSGISPVIFSIVFFALVLVLTIRPSKVVDIVGSILTPALLIALA
                     VLIVKGIVSPLGEIRDSSLIQNVFAEGITQGYQTMDALAASVFASIIIMSVIAKGYTG
                     EKEKMKATISAGVIAVIGMALVYGGLCYLGATVSQQYGQDVQQTALIVAITAALLGTT
                     GKILLAIIVALACLTTAIGLSSAAGQYFSTLTDGKLKYEHIVIVVCVFSAIISNFGVS
                     TIIKFSSPILSMVYPATITLVILALFSNKIKNDNVFKCAAYMALLVSVLTVATSFGVK
                     IPLVNSLPFASLGFNWIVPVVIAGIIGNFIPSKSSKTA"
     gene            complement(2540..3832)
                     /gene="brnQ"
                     /locus_tag="JAM15_18630"
     CDS             complement(2540..3832)
                     /gene="brnQ"
                     /locus_tag="JAM15_18630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HAT6800262.1"
                     /translation="MGKTKDVIVFGFALFAMFFGAGNLIFPPYLGIITGPEWLIAFLG
                     FTFADAGLALLAVMATAKFDGNVVEMFKRCGMKLGILIGCADILCIGPFLAIPRTGAT
                     TYEMGIMPLFGTSIPVLLFCILFFALSYVLTIRPSKVVDIVGQFLTPALLIALAFIII
                     KGIISPLGDIVDKPMIPNVFAEGIGQGYQTMDAFAAIALASVLIVSLNDKGYSTISDK
                     LKMIGKAGVLACGGLALVYGGLCFLGATVSTMYGTDAVQSQVIVNITEGLLGNVGKAI
                     LAVVVSLACLTTSIGLTSATGQYFSRLTKGKLSYEKIVLAVSVFSAVVASFGVGTIIK
                     IASPILSIVYPPSIVLIILAFFNEKIKNDNVYKGAVYMSLLVSILTVISSYGVDVPVV
                     KSLPLHSLGFNWVVPVIIAGIIGNFIPSKSQSNTLGTN"
BASE COUNT         1364 a          673 c          444 g         1463 t
ORIGIN      
        1 aaaaataaat ttatcaaatg agattaataa tgttcttttc tccacaataa tttaataatt
       61 cttttaaata taaaaaggaa ttgccatata atttaaaggc aattccacaa ttatcaatta
      121 gttttattat tatgcagttt tactgctttt agatggaata aagtttccta ttattcctgc
      181 tattacaact ggaactatcc agttaaatcc taatgaagca aatggtaagc tattaactag
      241 aggaattttt acaccaaaac ttgttgcaac tgttaataca cttactaata atgccatgta
      301 tgcagcacat ttgaacacgt tgtcattttt aattttatta ctaaataatg ctagtataac
      361 tagagttata gttgctggat ataccatact tagtatagga gaagagaatt ttattattgt
      421 acttactcca aagtttgata tgattgcact aaatacacaa actactataa ctatatgctc
      481 atactttaat tttccatctg taagtgttga gaaatattga ccggctgctg aagaaagacc
      541 tatagctgtt gttaaacatg ctaatgcaac tataatagcc aataaaattt tacctgtagt
      601 tccaagtaaa gctgctgtta ttgcaactat taaagctgtt tgttgaacat cttgtccata
      661 ttgttgagac acagttgctc caagataaca taatccacca taaactaatg ccattcctat
      721 tactgcaatt acacctgcac ttattgtggc tttcatcttt tctttctcac ctgtataacc
      781 tttagctatt actgacatga ttataattga tgcaaataca ctagctgcca atgcatccat
      841 tgtttgataa ccttgagtta taccttctgc aaatacattt tgaattaaag aactgtctct
      901 tatttctcct aatggagata cgataccttt aactattaat actgctaaag ctataagtaa
      961 agctggagtt aatattgacc caactatatc tacaactttt gatggtctta ttgttaaaac
     1021 caatactaga gcaaagaata ctatagagaa tattactgga cttattccag aacctattgt
     1081 aggcaatata cccatttcat aagttgttgc tgctgttcta ggtattgcta aaagtggccc
     1141 tatacagatt accattgcac atcctaatgc aatacttaat cctttgcctg ctcttgagaa
     1201 catcttcgat gtgtctccat tgaacttagt tgctgctata actgctaata atgccaaacc
     1261 accatctgca aaaaggaatc ctatgaaagc tattagccaa ctacttccag ataaaactcc
     1321 tagatatgga gggaagatta agttccctgc accaaaaaac attgcaaata gtgcaaatcc
     1381 aattacaatt acatctttaa aattgatttg tttctcaccc atttaaagca cccccatttg
     1441 aattttacta ccttttacta aaaaataagt ccaatctctt cattaaatga aaaccttttg
     1501 acgagatttt atttaattat acatttttga cttaaatttg tcaattatgt ttcataattt
     1561 ataaaatctt cacaatattt aatacaactt tcttaattaa acaaaatcaa cctgtatact
     1621 ttaaacatag ttggtttttt gttttttctc taatttttct tgataaaatt aactattcag
     1681 aacaattaaa atattaagac tttttagatt attcgtttta ttattaagtt gtattgcttt
     1741 atatactgta tatatcactc tcctttttac attcatataa tctttttaat tcaatttaaa
     1801 ttttaaatat tttgtgttta ttatataatc tgaaaaaaaa gcagtcaata gcatttttaa
     1861 tttttttaat tttcaaaatt atgattctta aaaaatcgtt ttccttttat cataacacct
     1921 attaacgtta attcttgtag tattttgtat ttattttgct aaattgacag ttaactttat
     1981 tcaattttta ttctactcac gtagatttac ctcttgtctt ttagtcttaa aaccattttt
     2041 tctgaaaatt ccttattatg atttatcaac ttatttttct tcatagcaat tactttctaa
     2101 cttccaactt acttaaactt tgcagttgct agtattcacg tttacatact tatatgtcat
     2161 aattaactaa aaattcttaa tatatctctc aatgaaaaca atttactcat ttatttaata
     2221 catttatata atcatatgtc ttaaatttta ttttattatt ttattattgt cacaatttta
     2281 tttatattat atttttgtaa aaatcattta atatgtatac ttaaatttat aaaattactc
     2341 taaaattctt ttttaatctc tattattgtt aaaaaataaa ctatatattt ttttgatatt
     2401 ttcttatact ctttccatat taaatacaaa taattaatta tagaatccca aaataaaagg
     2461 agttatttgt acaaataact ccttttactt ttagttaact catttattta caattgatta
     2521 tattttaatt aaacaaaact tagtttgttc caagtgtatt agattgactc tttgatggta
     2581 taaaattacc aattattcca gctattataa ctggtaccac ccagttaaat cctaatgaat
     2641 gaagaggtaa agattttact actggaacat ctactccata actagatata actgttagta
     2701 tacttacaag caatgacata tatactgctc ctttgtacac attatcattc ttaatttttt
     2761 cattgaagaa agctaaaatt attaaaacaa ttgatggtgg ataaactata cttagtatag
     2821 gagatgctat ctttattata gttccaacac caaaagatgc tactactgca ctgaatacag
     2881 atacagctaa tactattttt tcataactca atttaccttt tgtaagtcta gagaaatatt
     2941 gacctgtggc agatgtaaga cctatagatg tagttaaaca tgctaatgat actactactg
     3001 ctaaaatcgc tttcccgaca tttccaagta atccttcagt tatatttact attacttgtg
     3061 attgtactgc atctgttcca tacattgttg atacagttgc tccaaggaaa cataatcctc
     3121 cataaactag agctaatcct ccacaagcaa gaacccccgc cttaccaatc atttttaact
     3181 tgtcactaat agtagaatat cctttatcat ttaaagatac tattaacact gatgcaagtg
     3241 ctattgctgc aaaagcatcc attgtctgat aaccttgacc tataccttct gcaaatacat
     3301 taggtatcat aggtttatct actatatctc caagaggtga tataatacct tttataatta
     3361 taaatgctag agctattaaa agagctggag ttaaaaactg tccaactata tctacgacct
     3421 tagaaggtct tattgttagt acatatgaaa gcgcaaaaaa aagtatacag aataataaca
     3481 ctggaattga agttccaaat aaaggcatta tacccatttc ataagttgtt gcacctgttc
     3541 ttggtatagc taagaatgga cctatacata aaatgtctgc acaacctata agaatcccta
     3601 acttcatacc acatctttta aacatttcaa ctacgtttcc atcgaattta gctgtagcca
     3661 ttactgctag aagtgccaat ccagcatcag caaacgtaaa tcctaagaag gcaattaacc
     3721 attctggacc tgtaattatt cccaagtaag gtggaaatat taagttacct gctccaaaga
     3781 acattgcaaa taacgcaaat ccaaatacta taacatcctt ggtcttaccc attataaaat
     3841 cccccttttt aaccttatta aattaataaa atgtctcgat tgtttacgct tgcataagta
     3901 agttgaatta aacaataaga acttattatt aaattaataa aatt
//
LOCUS       DACTZW010000160         3894 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.163, whole genome shotgun sequence.
ACCESSION   DACTZW010000160 DACTZW010000000
VERSION     DACTZW010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3894
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.163"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            <1..428
                     /locus_tag="JAM15_18635"
     CDS             <1..428
                     /locus_tag="JAM15_18635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HAT6800263.1"
                     /translation="NATKIKDDKYKTKVFKGLVDAFIANLYSDMKQGEDVRSILLYML
                     REKQKLDINEFTEIAIKEDLKDSFKDHAEEKGIDGSFNIDKKWVEKNLKNRHIKTDTG
                     IEIKGKMDDFEDFMKYGIRHNGNGTVDIIIKNVSFYNEK"
     gene            437..1327
                     /locus_tag="JAM15_18640"
     CDS             437..1327
                     /locus_tag="JAM15_18640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016227206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HAT6800264.1"
                     /translation="MKIGLIDVDSHNFPNLPLMKISAWHKQQGDSVEWYEPLLSSYID
                     KVYMSKVFTDSKDYMWNINANEVIKGGTGYFYPEGGHVLDDEIEHQYPDYNLYNIRDT
                     AYGFLTRGCPRSCSFCIVSKKEGIKSKKVADVEEFWKGQKEIKLLDPNLLASKEHLEL
                     LGQLIKTKSYVDFTQGLDARLLTKENIELLKQVKIKTIHFAWDFMSETDKIIPKLKEF
                     KKETNLGYQKLKVYVLNNYDTTMEENLYRIYKLKELGYDPFVMVYDKPNACKEIRRLQ
                     RWANNKIIFRSVNKFKDYKG"
     gene            1335..1730
                     /locus_tag="JAM15_18645"
     CDS             1335..1730
                     /locus_tag="JAM15_18645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019123616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800265.1"
                     /translation="MDLPDNVIEIDILRINRNNDKKCKCKNREFIVDTVNKSVHCSEC
                     GFRVEPYDALYELAMNFERVNGQVNTLLKQRKEIASYKPHLIVFKRLESSYRGKKMLP
                     VCPICGEAFYFENLTSWINKDFYERRKNK"
     gene            1809..1994
                     /locus_tag="JAM15_18650"
     CDS             1809..1994
                     /locus_tag="JAM15_18650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800266.1"
                     /translation="MVITEFKVTWQTTREWEKGEVYSSIFTDLEEARAFKKDEENIKE
                     NYNVKLLSRTIVEIEID"
     gene            2017..2232
                     /locus_tag="JAM15_18655"
     CDS             2017..2232
                     /locus_tag="JAM15_18655"
                     /inference="COORDINATES: protein motif:HMM:NF024363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3850 domain-containing protein"
                     /protein_id="HAT6800267.1"
                     /translation="MIHELQIASSTFKDVIKNKKQIEVEHTVDFKAGDTVILQSFKDK
                     KFTGIEVNKEIEYFVKLGNGYVELGIK"
     gene            2246..2650
                     /locus_tag="JAM15_18660"
     CDS             2246..2650
                     /locus_tag="JAM15_18660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800268.1"
                     /translation="MQNKKDVWLYGWNNKYLSSDEYESKDEAIQAVKEELKEFGNFAE
                     SIYVGRKEKVNIPNIDVEEALEHIQEKIDDEVGECGEDWFENIRVEDILILENRISEV
                     FKKWIDEFGYKPYWFKFTDTEEIELNEVTNED"
     gene            2640..3047
                     /locus_tag="JAM15_18665"
     CDS             2640..3047
                     /locus_tag="JAM15_18665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HAT6800269.1"
                     /translation="MKINFTIDGEPIGKERPRMNSITKRTYTPNKTKSYEDLIKWLYQ
                     SKVKHYFEGYIKMTLRCYYSIAKSNSKKVKEQKRNNVLRPSKKPDIDNVVKIIADSLN
                     EIAYKDDTQIVEVVASKYYSDKPRVEVMLEDII"
     gene            3062..3787
                     /locus_tag="JAM15_18670"
     CDS             3062..3787
                     /locus_tag="JAM15_18670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor Ant"
                     /protein_id="HAT6800270.1"
                     /translation="MNEIMTNENLRVVADDLVTVYETDTGEKIVFARELHNNLEVKRQ
                     FIDWIEDRIKQYGFKENEDYSVFHKNMKNSTGGRPSKEYVLKLDVAKELAMVQNNNKG
                     REIRRYFIRLEKLLNRTLSNSQLSQINTIVNETLLKMEVKHNIQMEQLKKECSEYYRP
                     TSKTKYDISSYIKERLGISKVNEEFELVKKRTLLVLGADKWEDIPKDVLLNSLNLIDE
                     SIRIIKSERKTNQISFFEKDNFC"
BASE COUNT         1653 a          345 c          759 g         1137 t
ORIGIN      
        1 taaatgctac taaaattaaa gatgataagt ataagactaa ggtgtttaaa ggcttggtag
       61 atgcttttat agcaaattta tatagtgata tgaagcaggg agaagatgta agaagtatct
      121 tgctttacat gctaagagaa aagcaaaaac ttgatataaa tgagtttact gaaatagcaa
      181 taaaggaaga tttaaaagat agttttaagg accatgcaga agaaaagggt attgatggaa
      241 gttttaatat tgataaaaaa tgggttgaga aaaatctaaa aaatagacat ataaaaacag
      301 atacagggat tgagataaaa ggcaaaatgg atgattttga ggattttatg aaatatggta
      361 ttagacataa tgggaatgga actgtagata taattattaa aaatgtaagt ttttataatg
      421 aaaagtaggt gctcatatga aaatagggtt aatagatgtt gatagtcata actttcctaa
      481 tttaccattg atgaaaatct cagcatggca taaacaacaa ggagatagcg ttgagtggta
      541 tgagccttta ctatcaagct atatagataa agtttatatg agtaaagtat ttacagactc
      601 taaagactat atgtggaata taaatgctaa tgaagttata aaaggtggta cagggtattt
      661 ttatcctgaa ggtgggcatg tgctagatga tgaaatagaa catcagtatc ctgattataa
      721 cttgtataat attagagaca cagcgtatgg ttttttaact aggggttgtc caagaagttg
      781 ttcattttgt atagtttcta aaaaagaagg tattaagtct aagaaggttg cagatgtaga
      841 agaattttgg aaaggtcaaa aagaaattaa gttactagac cctaatttgc ttgcatcaaa
      901 agaacattta gaattacttg ggcaactaat aaaaactaaa tcgtatgtag attttacgca
      961 ggggcttgat gcaaggcttt tgaccaaaga aaatatagaa ttgttgaaac aagttaaaat
     1021 aaaaactatt cattttgctt gggattttat gagcgaaaca gacaaaataa ttccaaaact
     1081 taaagaattt aaaaaagaaa cgaatttagg ttatcaaaaa ttaaaggtat atgtattaaa
     1141 taactatgat acaacgatgg aagaaaactt gtatagaatt tataaactta aagaactagg
     1201 atatgaccct tttgtaatgg tttatgataa acctaatgcg tgtaaagaaa ttagaagatt
     1261 gcaaaggtgg gctaataata agattatttt cagaagtgta aataaattta aagattataa
     1321 ggggtgattt agaaatggat ttaccagata atgtcatcga aattgatata ttaagaatta
     1381 atagaaataa tgataagaag tgtaagtgca agaatagaga gtttatagta gatacagtca
     1441 ataaatctgt tcattgttca gaatgtggat ttagagtaga accatatgat gcactatatg
     1501 aactagcaat gaactttgag agagtgaatg gacaagtaaa cacattatta aaacagagaa
     1561 aagaaatagc cagttataaa ccacatttga tagtatttaa aagacttgaa agtagttaca
     1621 ggggtaaaaa aatgttacca gtatgtccga tttgtggaga agcattttat tttgaaaatt
     1681 taacttcatg gattaataaa gatttctatg aaagaagaaa aaataaataa aataaatagt
     1741 caaggtaagt ttgtgaatga aactagaatg ctatagactt actttgactt ataaaaggag
     1801 tcgtcgatat ggttattaca gaatttaaag taacttggca gacaacaaga gagtgggaaa
     1861 agggagaagt atatagctct atatttactg atttagaaga agcgagagct tttaaaaaag
     1921 atgaggaaaa tataaaagaa aattataatg tgaagctttt aagtagaact atagtagaaa
     1981 ttgaaataga ctaaaacttt taaagggtgt gagcttatga tacatgaatt gcagatagct
     2041 tctagtactt ttaaagatgt aattaagaat aaaaaacaaa ttgaagtaga gcatacagta
     2101 gattttaaag caggagatac agttatatta cagtcattta aagataaaaa atttacagga
     2161 attgaggtaa acaaagagat tgagtatttt gttaagcttg gaaatggtta tgttgagtta
     2221 ggaataaaat agaggaggaa tttatatgca aaataaaaaa gatgtgtggc tatatggttg
     2281 gaataacaaa tatttaagta gtgatgagta tgaaagtaaa gatgaagcta ttcaagcagt
     2341 taaggaagaa ctaaaagagt ttggaaattt tgcagaaagt atttatgttg ggagaaaaga
     2401 gaaagttaat atacctaata tagatgtaga agaggcatta gaacatattc aagaaaagat
     2461 tgatgatgaa gttggagagt gtggagaaga ttggtttgaa aatatacgtg ttgaagatat
     2521 attgatacta gagaatagga taagcgaagt atttaaaaaa tggatagatg aatttggata
     2581 taaaccatat tggtttaagt ttacagatac agaagaaata gaactaaatg aggtcacaaa
     2641 tgaagattaa ttttacaata gatggagaac caatcggaaa agaaagacct agaatgaact
     2701 ctataactaa aaggacctat acacctaata agactaagag ttatgaggac ctaataaaat
     2761 ggctatatca atctaaagtt aaacattact ttgaaggtta tataaaaatg actttaagat
     2821 gttattattc tatagctaaa agtaacagta aaaaggttaa agagcagaaa agaaataatg
     2881 tgttaagacc tagtaagaaa cccgatatag acaatgttgt taagattata gctgattcac
     2941 tcaatgagat agcttataag gatgatacac agattgttga ggttgtagct agtaaatatt
     3001 atagtgacaa accaagagtt gaagttatgc tagaggatat tatctaagga ggactataaa
     3061 tatgaatgag attatgacaa atgaaaattt aagagttgta gcagatgatt tagttacagt
     3121 ttatgaaact gatacaggag agaaaatagt ttttgcaaga gaactacata ataacttaga
     3181 agttaagaga cagtttatag actggattga agatagaatt aaacaatatg gatttaagga
     3241 aaatgaggat tattcagttt ttcacaaaaa tatgaaaaac tcaactggcg ggagaccttc
     3301 aaaagaatat gtattgaagc ttgatgtagc aaaagaactt gctatggtac aaaacaataa
     3361 taaagggaga gaaataagaa gatattttat aagattagaa aagttgctca atagaacctt
     3421 atcaaattca cagcttagtc aaattaatac tattgtgaat gaaacattac ttaagatgga
     3481 agttaaacat aatatccaaa tggagcaact taaaaaagag tgttcagaat attatagacc
     3541 aacctctaaa actaaatatg atatatcttc ttatataaaa gaaagactag gtatatcaaa
     3601 agttaatgaa gaatttgaat tagttaagaa aagaactcta ttggtattag gtgctgataa
     3661 atgggaggat ataccaaaag atgtattact taattcatta aacttaatag atgaatcaat
     3721 aagaattata aaatctgaaa gaaaaacaaa tcaaattagt ttctttgaaa aagataattt
     3781 ctgttaataa aaagaaaaaa ggagtgcttt cacactccac ttgtcaaaaa tataaaactt
     3841 ttatccaaaa ttattataac ataaacagga gtgtggaagt atggataata atat
//
LOCUS       DACTZW010000161         3814 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.164, whole genome shotgun sequence.
ACCESSION   DACTZW010000161 DACTZW010000000
VERSION     DACTZW010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3814
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.164"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            <1..798
                     /locus_tag="JAM15_18675"
     CDS             <1..798
                     /locus_tag="JAM15_18675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAT6800271.1"
                     /translation="ISKYKECYKPSIEQGAVVDMKVKTVLIVSNVNNIELKIDPTIIF
                     ATLKDIQDLETKIGTVNTKIDTTKTELTSNIETTKTELNTRIDTENEKQNIKIDQLIA
                     GGSNVASTQTIDIDDWVDDEEGRFKATVTHNLLTQRIVVNIIDATTKENVVTNFKIID
                     DNSIEIRSEVKVELNVYVINGNAETHFINATVDDNRVSEMTTYSSKKIEDSISSIQLI
                     DTSISITDANDRFTSDKLDGVLEEIMVEISGQRTKGITIVNNLIDMI"
     gene            815..1951
                     /locus_tag="JAM15_18680"
     CDS             815..1951
                     /locus_tag="JAM15_18680"
                     /inference="COORDINATES: protein motif:HMM:NF013507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kelch repeat-containing protein"
                     /protein_id="HAT6800272.1"
                     /translation="MATKLEENAKLREMIDTLETAKNDLQVGKNNIANILGSPFTGND
                     KLDTTKNTLNSIRSTFVSNLNKKGISTVSNTPFKILAENVGKIEQGNMRVPIWYTPKN
                     VVINGAFYSEIKDENYATAIEKDIFFFIKVSSSSMYFRKYNTITNSLTSLASPDYCVN
                     FLLISYNDTFYRIGGLVSSTALNTCKKYNTKTSTWSYLPNMSTSRFGAGGEMYLNQMH
                     VIYGKGKAGDSAAVNTAEFFLIDTNTWTTKGDLQFSKNSKYTCAKGSSNFIVYGLSDP
                     SNIYRRIIANYNPKAGTISGRFGTSESFSVPIKNCMYLGNYDYYYNDGCMGLLIGESG
                     ELFRTSKLERKSIPYNETTGAVSIENKFIYYCENGNVKCFIPEL"
     gene            2143..3276
                     /locus_tag="JAM15_18685"
     CDS             2143..3276
                     /locus_tag="JAM15_18685"
                     /inference="COORDINATES: protein motif:HMM:NF025330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800273.1"
                     /translation="MTIKLEEDSSIKEVMDSFENVKNDLQNAKDNLASTLGSPFVSTD
                     SFSTTKTKIQTFKSTLATNLTSKGVSTSSNETVQNMVSKVDDIELGNTDIPNWYKPKN
                     IIFDGVSSSLQQYPSCIAVENYIYFLCKNTLGLSLLRYDTLTNVNSSLARPSVCDDAL
                     MVYHGGYIYRIGGYNDSSAAPSCQRYNIKTNTWSYISNMITARGGTCGNTYSDEIHVL
                     YGYTDTNYDTTTSAISEYYKISTNTWSTKTNLPASRYRRLFVCSKTDTYTFCITGTTD
                     PSSYWDTCISSYKPSYGTITRLEGIHLGFATSINNMLYTVYYGDTYIYVGGYNHNGRV
                     FYKEYIKKGSTFPYNTLLKAVSVKNKFIYYCDDSRYKCFVPEL"
     gene            3295..3660
                     /locus_tag="JAM15_18690"
     CDS             3295..3660
                     /locus_tag="JAM15_18690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800274.1"
                     /translation="MIKIWDKKEKINGVSAEEILKGNYDFQTSEVFLILDDYNRVTNI
                     ESVNTIKSIYKLDKNLTALETAEKYLEMHKKQEEDIKAHEELEKNSKSAIIVTHEEVK
                     ALREETATLTFAMIEKGLI"
     gene            3663..3797
                     /locus_tag="JAM15_18695"
     CDS             3663..3797
                     /locus_tag="JAM15_18695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HAT6800275.1"
                     /translation="MWYKIIKKYYEDELWTKEQVKTAVEKNKITTIEYKNIVGEDYIV
                     "
BASE COUNT         1559 a          437 c          640 g         1178 t
ORIGIN      
        1 atttctaaat acaaagagtg ttataaacct tctatagaac aaggtgcagt ggtagacatg
       61 aaggttaaaa ctgtgcttat tgtatctaat gtaaataata tagaacttaa aattgaccca
      121 acaataatct ttgcaacact caaagatata caagacttag aaactaaaat aggtactgtt
      181 aatactaaaa ttgatacaac taaaacagaa ttaacaagca acatagaaac tactaaaaca
      241 gagctaaaca ctagaattga cacagaaaat gagaaacaaa atattaaaat tgaccaactt
      301 attgcaggtg gctctaatgt agcatctact caaacaatag atattgatga ttgggtagat
      361 gatgaagaag gtagattcaa ggcaactgta acacataact tattaacaca aagaatagtt
      421 gtaaatatta tagatgctac tacaaaagaa aatgtagtta caaactttaa aattatagat
      481 gataattcta tagaaattag aagtgaggta aaagttgaat taaatgtcta tgtgataaat
      541 ggaaatgcag aaactcattt tattaatgca actgtggatg ataacagagt gtctgaaatg
      601 actacttatt cgtctaagaa aatagaggat tctattagca gtatacagct tatagatacc
      661 agtataagta ttacagatgc taatgataga tttacaagtg ataagttaga tggagtatta
      721 gaggaaataa tggtagaaat aagtggtcaa agaactaaag gaataactat agtgaataat
      781 ttaatagata tgatttaata aaggagagtg aaaaatggca acaaaattag aagaaaatgc
      841 aaaactaaga gaaatgatag atacattaga aactgcaaaa aatgatttgc aagtgggtaa
      901 aaataatata gctaatattt taggttcgcc ctttacagga aatgacaagt tagatacaac
      961 taagaataca ttaaattcaa ttagaagtac ttttgtttca aacttaaata aaaaaggcat
     1021 atcaactgta agtaatacac cttttaaaat attagctgaa aatgtaggaa aaatagaaca
     1081 gggaaatatg agagtcccaa tttggtatac acctaaaaat gttgttataa atggagcttt
     1141 ttattctgaa ataaaagatg aaaattatgc tacagcaata gagaaagata tttttttctt
     1201 tattaaggtt agttcaagtt caatgtattt tagaaaatat aatactataa caaattcact
     1261 tacgagtctt gcatcaccag attattgtgt caatttctta ttaataagtt ataatgatac
     1321 attttaccga ataggtggat tagttagtag cacagccttg aatacttgta aaaaatataa
     1381 tacaaaaact tcgacttgga gttatttgcc taacatgagt actagtaggt ttggggcagg
     1441 aggtgaaatg tatttaaatc aaatgcacgt tatttacgga aaaggaaaag caggtgacag
     1501 tgcagcagtt aatacagcag aattttttct aatagataca aacacttgga ctactaaggg
     1561 ggatttacaa ttttctaaaa actctaaata cacttgtgca aaaggttcta gtaattttat
     1621 tgtgtatggt ttaagtgacc ctagcaatat ttatagaaga ataatcgcaa attataatcc
     1681 caaagcaggg actattagtg gcagatttgg tacatctgaa tctttttcag ttcctataaa
     1741 aaattgcatg tatctaggga actatgatta ttactataat gatggatgca tggggttact
     1801 tattggtgaa agtggtgaac tttttagaac ttcaaagctc gaaagaaagt caatacctta
     1861 taacgaaaca acaggagcag tgtctatcga aaataaattt atttattatt gcgaaaatgg
     1921 aaatgttaaa tgttttatac cagagttata aaattagtaa ctatttgttt agaaatggtt
     1981 acttaatact tttgtaatct ttgaatttac tatcttatac attaaagtaa attaatttaa
     2041 aatataaagc tgtttttaga atagtttaaa tttctatcta ttttactttt ttaagtaacc
     2101 atttctaaac gaaaggatac ttaaaaagga ggaaggaatt taatgactat aaaattggaa
     2161 gaagattcaa gtataaaaga agttatggac tcttttgaga atgtaaaaaa tgaccttcaa
     2221 aatgctaaag ataacttagc tagtacatta ggaagtcctt ttgtttcaac tgattcattt
     2281 agcactacta aaacaaaaat acaaactttc aagagtacat tagcaactaa tttaacaagc
     2341 aaaggtgttt caacttcttc aaatgaaacc gttcaaaata tggtaagtaa agttgatgat
     2401 attgaactag gaaatacaga cataccaaac tggtataaac ctaaaaatat aatttttgat
     2461 ggggtttctt caagtttaca acaatatcct tcgtgcatag cagtggaaaa ctatatatat
     2521 tttctttgta agaatacact aggtttgtcg cttttacgct atgatacgtt gacaaatgtt
     2581 aatagttctt tagcaagacc gtcagtttgt gatgatgcat taatggttta tcatggtggt
     2641 tatatttata ggataggtgg atataacgat agttcagctg ctccaagttg tcaaagatac
     2701 aatataaaga caaacacttg gtcttatatt tctaatatga ttacagctag aggtggaaca
     2761 tgtggaaata cttattccga cgaaatacat gttttgtatg gttatacaga tacaaattac
     2821 gatacaacaa caagtgctat cagtgaatat tataaaatta gtacaaacac ttggtcgact
     2881 aaaacaaatt taccagcttc tcgttataga aggttatttg tatgttcaaa aacagatacc
     2941 tacacttttt gtataacagg aacaacagac ccaagtagtt attgggatac ttgtataagt
     3001 agctacaaac catcttatgg tactattaca agattagaag gtatacacct tggttttgct
     3061 acaagtatta acaatatgtt atatacagtg tattatggcg atacatatat ttatgtaggt
     3121 ggatataatc acaatggtag agtattttat aaagaatata ttaaaaaagg ttctacattt
     3181 ccatacaata ctttacttaa agctgtatca gtaaagaata aatttatata ttactgtgac
     3241 gatagtaggt ataaatgttt tgtgccagaa ctataaaaaa ggagaaaata aaaaatgata
     3301 aaaatatggg ataaaaaaga aaaaataaat ggagtttcag cagaagaaat tttaaaaggt
     3361 aattatgatt ttcaaacaag tgaagtattt ttaatacttg atgattataa cagagttaca
     3421 aatatagagt cagttaatac aattaaatct atatataaac tagataagaa tttgactgct
     3481 ttagaaacag cagaaaaata tttagaaatg cataagaaac aagaagaaga tataaaagca
     3541 catgaagaat tagaaaagaa ttctaaaagt gcaattatag ttacacatga agaagtaaaa
     3601 gcattaagag aagaaacagc aacattaact tttgcgatga tagaaaaggg gttgatatag
     3661 aaatgtggta taaaataata aaaaaatact atgaggatga attatggact aaggaacaag
     3721 ttaagacagc agtagaaaag aataagataa caacaataga atataaaaat atcgttggag
     3781 aggattatat tgtatagtcc ttttttaatt ttat
//
LOCUS       DACTZW010000162         3807 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.165, whole genome shotgun sequence.
ACCESSION   DACTZW010000162 DACTZW010000000
VERSION     DACTZW010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3807
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.165"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            265..1065
                     /locus_tag="JAM15_18700"
     CDS             265..1065
                     /locus_tag="JAM15_18700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HAT6800276.1"
                     /translation="MESKTKYIGISILILLMIFLIAKNFNGKLEIPIPESNSRKFKSA
                     AVFYPQHQDDEVLWGGSAIVDAIKQCGVDNVYVVLVSDGSGVNVFKANTKFRNLTRKQ
                     KEELRNNEFKSALRELGVKPQNVIILADIDKKEGTHYELMEKTILDFEHKFKGNVTHI
                     AHHYKYDDHIMHRKNGEVLKKLKREGKIKDDLYFVKPKYVKYIPRNERAIYKAMDFDD
                     YNKVKSACYEYKVVNSKRKMYGIGYISAHSYFEHLLNDPELTSVLSED"
     gene            1592..>3807
                     /locus_tag="JAM15_18705"
     CDS             1592..>3807
                     /locus_tag="JAM15_18705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HAT6800277.1"
                     /translation="MSNEFIILKGCKENNLNNISLKIPKRKITIFTGVSGSGKSSIVF
                     ETIAKESQRQLNERFSTFVRSFLPKYGEVKADCIENLSTPIIIDQSRLGGNSRSTLGT
                     ITDVNSFLRALYSRFGSEYIGNANMFSFNDIDGMCPHCHGLGKKLVPNMNQILDMNKS
                     LNEGAILLSGFGVGSWHWNIFAESGFFDINKRICDYSEVELEKFLHGKAEKIKIENAG
                     QTNMTYEGLMVKFNRLYLSRDGEISEATKKKLSKLLIEDRCPICDGRRLNEGVYRSLI
                     NGYNIADLTSMQIDELAEVIKSINEPEAQPLIKGIIEKLNSIIDIGLGYLTLDRETSS
                     LSGGESQRIKMVKYLNSNLVDLMYIFDEPSVGLHPKDVYKLNNLLKKLRDKGNTIIVV
                     EHDPDVIKIADHVVDVGPKAGKYGGKVVYEGSYKNLLTSGTLTGNALSKFLPIKESVR
                     EHSGYLEIKNCNKNNLKNVSIKIPKGVLTLVTGVAGAGKSTLIKDEFLKQNPSAVLID
                     QSPVSANSRSSLATYSGIMNNIRSIFSKTNGVNASLFSSNSEGACDNCKGSGIVEMNL
                     AFMESIKSTCNVCEGKKFKKEVLEYRFQGKNIIEVLEMSVLDAIEFFNLKQIKTKLQC
                     IEKMGIGYLTLGQTLDTLSGGECQRLKLASELNKESSVYILDEPTTGLHMADIENFIS
                     IIEEIVDNGNTVIIIEHNIDVIKRADWIIELGPEGGTKGGRVIFEGIPKQLCNNKIS"
BASE COUNT         1458 a          383 c          733 g         1233 t
ORIGIN      
        1 tttttaagct taataaattt taagaattaa gaagctttct ggctgtaata tttgcaatgt
       61 tgcagttaga aggctttttt attttattat agttcgtgtc aaagattgta tgaaacaata
      121 aaatattgta aaataatttg tatatttaga cctgattgac acaaaggttt ataagatatt
      181 tgagttgatt atacgaaatt ctatgaagta gtaaccctgt gactttaatc atgggaggtt
      241 cagaagaagg agaaaatttt aaatatggaa agtaaaacga agtacatagg aataagtata
      301 ttaatattat taatgatatt tttaattgca aagaatttta acggaaaact tgaaatacct
      361 attcctgaga gtaatagtag aaaatttaaa tcagcagcag tgttttatcc tcaacatcaa
      421 gatgatgagg ttttatgggg aggaagtgcc attgtagatg ctataaaaca gtgtggtgtt
      481 gataatgtat atgtggtatt agtatcagat ggttctggag ttaacgtttt caaagctaac
      541 acaaaattta gaaacttaac taggaagcaa aaggaagagc ttagaaataa tgagtttaaa
      601 tcagctttga gagagcttgg agtgaaacct caaaatgtga ttatacttgc agatatagat
      661 aaaaaggaag gcacacatta tgaattaatg gaaaagacta tattggattt tgaacataag
      721 tttaaaggca atgtgaccca tatagcccat cactataagt atgatgacca tataatgcat
      781 agaaagaatg gggaagtttt aaagaaactt aaacgtgaag gtaagataaa agatgacttg
      841 tattttgtta agccaaaata tgtaaagtat ataccaagaa atgaaagagc tatctataaa
      901 gcaatggatt ttgatgacta caataaggtt aagagtgctt gttatgaata taaggttgta
      961 aattcaaagc gtaaaatgta tggtatagga tatatttcgg cacatagtta ttttgaacat
     1021 cttctaaatg accctgaact tacgtctgta ttaagtgaag attaatttct tataagtagt
     1081 aagttatgtt tgataagttg attggagttt tctatagttt tgaaggtatt gaaaatttag
     1141 ttttatttaa agagttaaag atagaggttt ttaatgttta aaattttaaa gttaagttga
     1201 ataattgtat agaattattt gtgaaagaag aaacagtgta aaacatagta tcttatttat
     1261 ggttttaaaa tcataggcaa gatacttttt ttatgtaact aataccattt tgaggttatt
     1321 aacttaagaa ttttatataa tttaacactc atatataatg atgatattta ggtagaatag
     1381 atgcaattgc gcttaaataa aataactgta ttttttataa aaatcaaacc ctacactata
     1441 ctaccagata aaatctacat gctataattt gacctgtgtt tataaaaaaa ggagtaatct
     1501 aataaaatag tatttcactt atgtataact aacaactatt attacgattt tctctaaata
     1561 atttaaagaa aaataatgca ggaggtaaaa tatgagcaat gaatttataa ttttaaaagg
     1621 ttgcaaagag aataatttga acaatatttc cttaaaaata ccaaaaagaa aaataaccat
     1681 attcacaggg gtgtcgggtt ctggaaagtc atctattgta tttgagacaa ttgcaaaaga
     1741 atcacaacgc caactaaatg aaaggtttag tacatttgta agaagctttt tacctaagta
     1801 tggagaggtt aaagctgatt gtatagaaaa tctgtcaaca ccaattatca tagaccaaag
     1861 tagacttggt ggaaattcaa ggtcaaccct aggtactatt acagatgtaa attccttttt
     1921 aagagcttta tattcaaggt ttggtagtga gtatataggt aatgctaata tgttttcttt
     1981 taatgatatt gatggtatgt gcccacactg tcatgggctt ggaaaaaaac tagttcctaa
     2041 tatgaaccaa attcttgata tgaataaatc attaaatgaa ggtgctatat tgctttcagg
     2101 gtttggagtg ggttcttggc attggaatat attcgctgaa tcaggatttt ttgatattaa
     2161 taagaggata tgtgattatt cagaagtaga attggaaaag tttttgcatg gtaaagcaga
     2221 aaagattaag atagaaaatg ctggtcaaac taacatgaca tatgagggat taatggttaa
     2281 atttaatcgt ctatacttaa gtagagatgg agaaatatct gaggctacta agaaaaaatt
     2341 gagtaaactt cttatagaag atagatgtcc tatatgtgat ggaagaagac ttaatgaagg
     2401 agtatatagg tctttaatta atggttataa tatagcagat ttaactagta tgcaaattga
     2461 tgaattggct gaagttatta aaagtataaa tgagccagaa gcacaacctt taattaaagg
     2521 aataatagaa aagttaaaca gtatcataga tataggtctt ggatatttaa cactggatag
     2581 agagacatct tctctatcag gaggggaatc tcagcgtata aagatggtta agtatttaaa
     2641 tagtaatctt gttgatttaa tgtatatttt tgatgaacca agtgtaggac ttcatccaaa
     2701 agatgtgtat aaattaaata atcttttaaa aaaattgcgt gataaaggga atacaattat
     2761 agttgttgaa catgacccag atgttattaa gattgcagac catgttgtag atgtaggacc
     2821 aaaggcaggt aagtatggtg gaaaagttgt gtatgaaggc agttataaaa atctacttac
     2881 aagtggtact ttgacaggga atgctttaag taaatttctt cctattaaag aaagtgtaag
     2941 agaacatagt ggatatttag aaattaaaaa ttgtaataaa aacaatttaa aaaatgtatc
     3001 tattaagata cctaaaggtg tattgactct agttactgga gtagcaggag caggtaaaag
     3061 tacgttgatt aaggatgaat ttttaaagca aaatcctagt gctgtactta tagaccaaag
     3121 ccctgtttca gcaaattcaa ggtcgagttt ggcaacatat agtggaatta tgaacaacat
     3181 aagaagcata ttttcaaaaa caaatggcgt aaatgcttct ttattcagtt caaattcaga
     3241 aggagcttgt gataactgta agggttctgg aatagtagaa atgaatcttg cttttatgga
     3301 gagtataaag agtacctgca atgtttgtga aggtaaaaaa tttaaaaaag aagttttaga
     3361 atataggttt caagggaaga atataattga agttcttgaa atgtctgttt tagacgcaat
     3421 tgagtttttt aatttaaaac agattaaaac gaaattacaa tgtattgaaa aaatgggtat
     3481 tggatacctt actttaggac aaactcttga tactttgtct ggaggagagt gtcaaagatt
     3541 aaagcttgct agtgaattaa ataaggaaag ttcagtgtat atattagatg aaccaacaac
     3601 aggtcttcat atggctgata ttgagaattt tataagtata attgaagaga ttgtagataa
     3661 tggaaatacg gtcataataa ttgaacacaa tatagatgta attaaaagag ctgattggat
     3721 tattgagctg ggacctgaag gagggacaaa aggcgggaga gtaatatttg aaggtatccc
     3781 aaaacaatta tgtaacaata aaatatc
//
LOCUS       DACTZW010000163         3799 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.166, whole genome shotgun sequence.
ACCESSION   DACTZW010000163 DACTZW010000000
VERSION     DACTZW010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3799)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3799)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3799
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.166"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(27..908)
                     /locus_tag="JAM15_18710"
     CDS             complement(27..908)
                     /locus_tag="JAM15_18710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAT6800278.1"
                     /translation="MNKGNCILGEILIMIIQQIYNNNVVLVLDENIKKELILTGCGIG
                     FQKKKGQEIDKSKIERTFVIQDESFLDKISKLASQVDEKFFEISTEIIAYAEENLNTK
                     LYEYIYVALTDHIAFAIKRYHENITIKNDLLHEIKRIHKKEYEIGKWAVDYINKEFDV
                     KFPVDEAGFIAMHIVNSNYKGSSKESLLITKIVKDILNIIRYYYRVEFKEDDINYDRL
                     LTHLKFFAKRLVKKEKINDTNNEIIDIIKVKYEKDYDCAYKIKTHVEKNYDYYVSQDE
                     LLYLTLHIKRVISVLNL"
     gene            complement(1116..1610)
                     /locus_tag="JAM15_18715"
     CDS             complement(1116..1610)
                     /locus_tag="JAM15_18715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAT6800279.1"
                     /translation="MSILVTLLGLLVCTTISTVFSKKWSNIPLAIYQIVLGIILSILP
                     FKFSFSFNPEIFVICIIAPLLFSEGQNVSRKELLELRKPILLLAFGLVLITVFAGGIF
                     IHFLIPGMPLSVSLALAAVISLTDLVAVKSITQGLNFPKNMMSILEGESLLNDDDRII
                     NIME"
     gene            complement(1762..2733)
                     /locus_tag="JAM15_18720"
     CDS             complement(1762..2733)
                     /locus_tag="JAM15_18720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP-binding protein"
                     /protein_id="HAT6800280.1"
                     /translation="MKKEESLLKVEGLKKYFEVKSGLFDKEIKCVKAVDGISFDLKKG
                     ETLAIVGESGCGKSTAGRTILRLIEKTEGKVEFNGVDIYKLEKEELRKLRPKMQMIFQ
                     DPYSSLNPRLNVEQIISEAVIEHNLVPKNEIKDNILNVVESCGLSKYHLNRKPDEFSG
                     GQRQRIGIARALALNPEFIVCDEPVSALDVSIQSQIINLLMDLQDKYKLSYLFISHDL
                     SVVNHIAHRVCVMYLGSIIEIATKGELYLHSQHPYTKALMSAVPVQDPTIKKNRIILK
                     GDIPSPTNPPSGCKFHTRCPYCKEICKKEIPVLKEISRNHFVACHLV"
     gene            complement(2734..3711)
                     /locus_tag="JAM15_18725"
     CDS             complement(2734..3711)
                     /locus_tag="JAM15_18725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6800281.1"
                     /translation="MSKALIEVKDLKVYFHTDKGIVKSVNEVSFNINEGETIGIVGES
                     GCGKSVTAMSLMKLLPTSKIEGGEIIFRGKDILKMNEDELMGIRGNEISMIFQEPMTS
                     LNPAFTVGSQIIEGIMIHQDLSKEEAKKKVIDMIKLVEIPRAEEIYNSYPHELSGGMR
                     QRIMIAMALSCNPKLLIADEPTTALDVTIQAQILDIMKNIKEKLNTSIMMITHDLGVV
                     AEMCDKVLVMYAGKIIEVAEVVELFKNPKHPYTIGLLKSKPILGKNKDKRLYSIPGQV
                     PNPIGIPDSCYFSDRCEKVCDKCRTQIPPLIELNSSHSIACWLYKKEEI"
BASE COUNT         1230 a          655 c          376 g         1538 t
ORIGIN      
        1 tacattctgt attaaactac tctttattat aaattcagta cagatataac tcttttgata
       61 tgtaatgtta aataaagtag ttcatcttga cttacatagt aatcataatt cttttctaca
      121 tgagttttta ttttatatgc acaatcataa tccttttcat actttacttt aattatatct
      181 ataatttcat tatttgtatc attgattttt tcttttttta ctaatcgttt tgcaaagaat
      241 tttaaatgag tcaaaagcct atcataattt atatcatctt ctttaaattc aactctataa
      301 taatatctta taatatttag tatgtctttt acaattttag taattaacag tgattccttt
      361 gaacttccct tatagtttga atttactata tgcattgcta taaaaccagc ttcatctact
      421 ggaaatttca catcaaattc tttatttata taatctacag cccatttacc aatctcatat
      481 tcttttttat gtattctttt tatctcatgt agtaaatcat tctttatagt tatattttca
      541 tgatatcttt taattgcaaa tgcaatatgg tcagtaagtg ctacataaat atattcataa
      601 agcttagtat tcaaattctc ctctgcataa gcaattattt cagtactaat ctcaaaaaat
      661 ttctcatcaa cctggcttgc tagtttgcta attttatcta aaaagctttc atcttgtatt
      721 acaaaagttc tttcaatttt acttttatct atttcttgac ctttcttttt ttgaaaccca
      781 atcccacatc ctgttagtat taattctttt tttatatttt catctaaaac taatacaaca
      841 ttattattat aaatttgttg aataatcata atcaatatct ctcccaaaat acaatttccc
      901 ttattcataa aaaaatacct aaattaagat acaattcacc tgtatacctt aacctaggta
      961 ttgcctgctt accagtaaca atccagcttg ttaattctta tatattgtat tcaatttatg
     1021 gttttattct attataaata aatatatatg tcaagtaaat tattgaaaac tatttcctat
     1081 tttttagtat tatttttaac atcaaaaatc aaattttatt ccattatatt tatgattcta
     1141 tcatcatcat ttaataaaga ttcaccttca agtatactca tcatattttt aggaaaattt
     1201 aatccttgtg tgattgattt tactgctact aaatcagtta gagatattac tgctgccaaa
     1261 gcaagtgaaa cagataatgg catcccagga ataagaaaat gtataaagat tccacctgca
     1321 aatacggtta tcaaaactaa accaaatgca agaagcaaaa ttggttttct aagctctagt
     1381 aactcttttc ttgatacatt ttgtccttca ctgaataata atggagctat gatacatatt
     1441 acaaatattt ctggattaaa tgaaaatgag aatttaaatg gcaaaataga caatataatc
     1501 cctagtacaa tttgatatat tgcaagagga atattactcc actttttgct aaatacagtt
     1561 gaaatcgttg tacaaaccaa taatcccaac aatgttacta aaattgacat aactacctct
     1621 cttttcaata ataatattat aaattaaact tatatatcaa ctaacttaat attaacaaca
     1681 tgaaatccca tcttaatcaa aaaaattttc agtttattct attattctta ttatatacat
     1741 caaatttaat ttttgaaata tctatactag atggcatgca acaaaatgat ttcttgatat
     1801 ttcttttaaa actggaatct cttttttgca tatttcctta caataagggc atcttgtatg
     1861 aaacttacat ccacttggtg gatttgttgg agatggtatg tctcctttta atataattct
     1921 atttttctta attgtagggt cttgtactgg tactgcgctc ataagtgctt ttgtatatgg
     1981 atgttgagaa tgtaagtaaa gttctccttt agttgcaatt tctattatag aacctagata
     2041 cataacacaa actctatgtg caatatgatt tactacactc aaatcatgag atataaataa
     2101 atatgagagt ttatatttat cctgtaaatc cataagtaaa tttataattt gagattgaat
     2161 agaaacatct agtgcagaaa caggttcatc acaaactata aattctggat ttaatgctaa
     2221 tgctcttgct atacctatcc tctgtctttg acctccagaa aactcatctg gttttctatt
     2281 taaatggtac ttagaaagac cacaactttc tacaacattt aatatattat cttttatttc
     2341 attctttggc actaaattat gttctataac tgcctctgat attatttgtt ccacatttaa
     2401 tcttggattt aatgaactat atgggtcttg aaatatcatt tgcattttgg gtcttaactt
     2461 tctaagttct tccttctcta acttatatat atctacacca ttaaattcaa ctttaccttc
     2521 agttttttca attaatctaa ggatggttct tcctgcagtt gattttccac atcccgattc
     2581 tccaactata gccaaagttt ctcctttttt taaatcaaaa gaaattccat ctactgcctt
     2641 tacacattta atttccttat caaataatcc agatttaact tcaaagtact ttttaagacc
     2701 ttctactttt aataaactct cttctttttt caattatatc tcctcctttt tatataacca
     2761 acatgcaata ctatgactac tattcaattc tattaaagga ggtatctgag ttctacattt
     2821 atcacatact ttttcacatc tatcactaaa ataacatgaa tctggtattc caattggatt
     2881 tggtacttgt cctggaatcg aatacaatct tttatctttg ttttttccaa gaataggctt
     2941 tgattttaga agtccaatag tataaggatg ttttggattt ttaaataatt caacaacctc
     3001 tgccacttct ataattttac cagcatacat cactaatact ttgtcacaca tttctgcaac
     3061 tactcccaaa tcatgtgtga tcatcattat agatgtgttt aatttttctt ttatattttt
     3121 cattatatct aaaatctgag cttgaatagt aacatctaaa gctgttgttg gttcatcagc
     3181 tataagtaat tttggattac atgataaagc catagctatc attattcgtt gtctcatacc
     3241 acctgataat tcatgtggat atgaattata tatttcttca gctcttggta tttctaccag
     3301 ttttatcata tcgattacct ttttcttagc ttcttccttt gataaatctt gatgtatcat
     3361 aataccttca atgatttgac ttccaacagt aaacgctggg tttaaagatg tcattggttc
     3421 ttgaaaaatc attgatatct cattccctct tattcccata agttcatctt cattcatctt
     3481 taaaatgtct ttgcctcgaa agattatttc tccaccttct atttttgatg ttggaagtaa
     3541 cttcatcaaa gacatggctg ttacagactt accacatcct gattctccaa ctattccaat
     3601 agtttcacct tcatttatat taaaacttac ttcatttaca ctctttacaa tccctttatc
     3661 tgtatgaaaa taaactttta aatctttaac ctcaattagt gctttactca ttattttctc
     3721 ctctcagcaa aattacttaa aataacatac accttttgat tgtattttat aaaaatttaa
     3781 attacaacat tttcttaca
//
LOCUS       DACTZW010000164         3764 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.167, whole genome shotgun sequence.
ACCESSION   DACTZW010000164 DACTZW010000000
VERSION     DACTZW010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3764
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.167"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(441..2828)
                     /gene="cadA"
                     /locus_tag="JAM15_18730"
     CDS             complement(441..2828)
                     /gene="cadA"
                     /locus_tag="JAM15_18730"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HAT6800282.1"
                     /translation="MEANNLIKKEFILGGLNCAHCAEEINNKVSKLQEVKSSNLNFIN
                     KKLIVNIKESFNEDTTIEKIIDIIDSTEPGLDIQISSKENASSKTSIKKELILGGLNC
                     AHCAEEINNKVSKLKEVESSNLNFVNKKLTVNISNNFKEDDVINKIKEIINSTEPGLD
                     IQVGSTDKVKGRTTEKSGAVNDTNKKELVPLIIGALVYIFGIYQTATGYESQFSNIVF
                     IVAYVIVGGDVLLRAIRNISKGRVFDENFLMALATVGALAIGESSEAVGVMLFYKVGE
                     YLQGVAVGKSRKSITSLMQIRPDYANLKFNSEVKVVSPEEVNVGDIIVVKPGEKVPLD
                     GVVVDGVSMLDTSALTGESVLREVEKGDEILSGVINKNALLSIEVTKSFGESTVSKIL
                     DLVENSSIKKSKTENFISKFSRYYTPIVVIAALLIAFVPPLVISGEVFSDWLYRGLIF
                     LVVSCPCALVLSIPLSFFSGIGFASKNGILIKGSNYLEALRSVDTVVFDKTGTLTKGV
                     FNVTKLNPEGISEEELLEYAAIAEVNSNHPIAKSILSYYNKKIDLDTIDSYEEIAAYG
                     IRVKHNGNFILAGNEKLMKKENISYSSAKEVGTVVYIAVDKVYRGYIVISDEVKEDSK
                     NAIRSLKAIGVKEVVMLTGDNEKVAKNIAQELELDTVYSNLLPNEKVDRLEDLYEGRT
                     EKEKIAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVLMTDEPSKISKAIEIA
                     NKTNKIVWQNIIFALGVKIIVMILGAGGVATMWEAIFADVGVALIAVVNAMRAMR"
     gene            complement(2851..3216)
                     /locus_tag="JAM15_18735"
     CDS             complement(2851..3216)
                     /locus_tag="JAM15_18735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HAT6800283.1"
                     /translation="MREEINDCNCNIIHEEIVTEAKSTMPDEEMLYDLAELFKVFGDT
                     TRVKILYALFANEMCVCDIASLLNMTHSAISHQLRVLKQARLVKFRREGKTVYYSLDD
                     SHISQIFDCGLNHIRETYK"
     gene            3415..>3764
                     /locus_tag="JAM15_18740"
     CDS             3415..>3764
                     /locus_tag="JAM15_18740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800284.1"
                     /translation="MSNKKKKDLDTSYMPYLDPANYADYITNEEIPQDELRNDPQISN
                     GYTKIPNNQNINNLYPNNVNHYPKSSNSPNNLPNTNNTSGNMNYNTSATNNMPNNMNN
                     NTGMPNNMSNNMNS"
BASE COUNT         1243 a          688 c          375 g         1458 t
ORIGIN      
        1 cttaaaaata tttcgtcaat acttttttaa attatttttt aaaaatattt actttcttat
       61 attacataat ttattgaatg acagtcatac tgttggttta gagtatttta acacacacat
      121 tttgttgtaa aaattataac tattaatata atatatatac aatcataagt attataattt
      181 ttatgaatct aatttaaact taatataaac ttattaataa accttctatg tctaaatttt
      241 aaaattacaa tataaaagct ctacactaaa taaatacatt aaataaacac aatggataat
      301 gaatataaat ttatatatgc aaagcgctcc aataaaaagg taccaataaa gttaaaagaa
      361 acttattgat acctttcatt attacatact tcaatatata attataagtt ttttaaatag
      421 tatggattta catttatccc ttatctcata gctctcatag catttactac tgctataagt
      481 gccacaccta catcagcaaa tatagcttcc cacatagtag ctactcctcc agcacctagt
      541 atcataacta taatttttac tcctagagca aatattatgt tttgccacac tatcttatta
      601 gtcttgtttg ctatttcaat tgctttagat atcttgctag gctcatctgt cataagcact
      661 acatctgcag cttcaatagc agcatctgaa cctaagcctc ccatagctat accaacatca
      721 gcacgagcta atactggagc atcatttatt ccatcaccta caaatgctat tttctctttt
      781 tcagttcttc cttcatataa atcttctaat ctatctacct tttcattagg aagtaaattt
      841 gagtaaactg tatccaattc taattcttga gcaatatttt ttgctacttt ctcattatct
      901 ccagttaaca ttacaacttc ttttacccct attgctttta agcttcttat ggcattttta
      961 ctatcttctt ttacttcatc agatataact atataacctc tatatacttt atcaacagca
     1021 atatagacta ctgtgcctac ttctttagct gatgaataag atatattttc ttttttcata
     1081 agtttctcat tacctgctaa tataaaattg ccattatgct ttactctaat tccataagct
     1141 gctatttcct cataactgtc tattgtatct aaatcaattt ttttattata gtaacttaat
     1201 atagactttg ctattggatg atttgaattt acctccgcaa tagctgcata ttctaataat
     1261 tcttcttctg atataccttc aggatttaac ttagttacat tgaacacacc tttagtaagt
     1321 gttcctgttt tatcaaatac tactgtatct acacttctta aagcttctaa ataattactt
     1381 cctttaataa ggataccatt tttagatgca aacccaattc cactaaagaa actaagtggt
     1441 attgataaaa ctaatgcaca agggcaagaa acgactaaga atatcaatcc tctatataac
     1501 caatcactaa atacctcacc tgagattaca agtggtggca caaatgctat taataaagca
     1561 gctattacta ctattggagt atagtatctt gaaaacttag atataaagtt ttctgtcttt
     1621 gattttttaa tgctagaatt ttcaacaagg tcaagaatct tagaaactgt tgattctcca
     1681 aaactctttg taacttcaat actcaataaa gcatttttat ttataacacc tgataagatt
     1741 tcatctcctt tttcaacttc tctcagcact gactctcctg tgagtgcaga agtatctagc
     1801 atagaaactc catccactac tacaccatct aatggtactt tttcaccagg ttttactact
     1861 attatatcac ctacatttac ttcttctggt gacactacct taacttcaga attaaatttt
     1921 agatttgcat aatctggtct tatttgcata agtgaagtta tagactttct ggatttacca
     1981 actgcaacac cttgtaaata ctctcctact ttatagaaaa gcataacccc tactgcttct
     2041 gatgactccc ctattgctaa tgctcctact gttgctagag ccatcaaaaa gttctcatca
     2101 aatactcttc cttttgatat atttcttatt gctcttaaaa gcacatcgcc acctactatt
     2161 acataggcaa ctataaatac tatattgcta aactgacttt cataacctgt agctgtttga
     2221 tatataccaa atatatatac aagtgctcca attataagtg gaactaattc tttcttattt
     2281 gtatcattta cagctcctga tttttcagta gttctccctt ttactttgtc agtagaccct
     2341 acttgtatat caagtcctgg ctctgttgaa tttattattt cttttatttt atttataaca
     2401 tcatcctctt taaagttatt acttatattt actgtaagtt ttttatttac aaagtttaaa
     2461 ttagaagatt caacttcttt taatttagaa accttgttat taatctcctc tgcacaatgt
     2521 gcacagttta atcctcctaa tataagctct tttttaattg atgttttact agatgcattt
     2581 tctttagaac ttatttgtat atcaagacct ggttctgttg aatctattat atctattatc
     2641 ttttctatag tagtatcctc attaaagctt tcctttatat ttactataag ttttttattt
     2701 ataaaattta agttggaaga tttaacttct tgtagtttag aaactttatt attaatctcc
     2761 tctgcacaat gtgcacagtt taatcctcct agtataaatt cttttttaat taaattattt
     2821 gcttccatat atattcactc ctctcattta tcatttataa gtctctctaa tatgatttaa
     2881 tccacaatca aatatctggc ttatatgact atcatctaat gagtaataca ctgtttttcc
     2941 ttctcttcta aactttacta atctagcctg ctttagtact ctaagttgat gagatattgc
     3001 agagtgagtc atatttaata aactcgctat atcacataca cacatttcat ttgcaaataa
     3061 tgcatataat atctttactc tagtagtatc cccaaatact ttaaataatt ctgctaaatc
     3121 atataacatc tcttcatctg gcatagttga tttagcctct gttactattt cttcatgtat
     3181 tatattacaa ttacaatcat ttatctcttc tctcatcttt aatcctccat tgttttaata
     3241 tatgaataac tgttcatatg ttcattatat gctatcattc ctaaatttgc aacaataatt
     3301 tttattaatt taatataatt agaatgcaca tattataaac ttttttaata tatatattat
     3361 tagaataagt ttttgtaaac ttttttatag ttttctagga ggtgcaagtt taatatgagt
     3421 aacaagaaaa aaaaggattt agatactagt tacatgcctt acttagaccc agcgaactat
     3481 gcagattata ttactaatga agaaattccc caagatgaat tgagaaatga ccctcaaatt
     3541 tctaatggtt atacaaaaat acctaataac cagaacataa ataacctata tcctaataat
     3601 gtaaatcatt atcctaaaag tagtaattct ccaaacaact tgcctaacac aaataataca
     3661 tccggaaata tgaattacaa tacatctgct acaaataata tgcctaataa catgaataat
     3721 aatacgggta tgcctaataa tatgtctaac aatatgaata gtaa
//
LOCUS       DACTZW010000165         3564 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.168, whole genome shotgun sequence.
ACCESSION   DACTZW010000165 DACTZW010000000
VERSION     DACTZW010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3564)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3564)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3564
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.168"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            400..1155
                     /locus_tag="JAM15_18745"
     CDS             400..1155
                     /locus_tag="JAM15_18745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAT6800285.1"
                     /translation="MLQIKNLSKSFPSPYGEPNTIFENLSIDIEDGEFVSIIGSNGTG
                     KSTLLNIISGLIKESSGQITLDSTTITNLAEYKRTQIVSRVFQDPSLGTCPSMTVREN
                     LSLALNKGKLLNLKKCLRHKTNNLEHLLEGISLDLKKYLDIKVQYLSGGQRQSLSLIM
                     SSLASPKVLLLDEHTAALDPKTSNEVIELTDKIVREKNITTLMVTHNLKHALQYGDRL
                     IMLHKGEVVLDVKDKEKENLTVEEILEKFEYAV"
     gene            1252..2289
                     /locus_tag="JAM15_18750"
     CDS             1252..2289
                     /locus_tag="JAM15_18750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAT6800286.1"
                     /translation="MIKSKKILSLIIAGVLGVSMLTGCSQNDGSNASNENKKTDSKKQ
                     KNIGISQLVEHPSLDKAKKGFIKALEDKGYKDGDNIKIDFQNAQNDMPTTQSIASKFV
                     SDKKDLIYAISTPSAQAAYNATKDIPIIMTAVTDPVEAGLVKSLEKPGGNVSGTSDYL
                     SIDKTLELVKTLTPKAKKIGVIYNTSEVNSKIQVDSLHDYAKKNNYEVVEKGISTSSE
                     VNQAISSLVGKIDVLYVPTDNLIVSSMPIVSKVANENKIPIIASEEGSVSSGALACCG
                     IDYEKLGYKAGELAIEVLEGKSVGDIPVTTLDETEIIINEDTLKALDMQKLSADNIKY
                     IKSDENAKSAK"
     gene            3098..>3564
                     /locus_tag="JAM15_18755"
     CDS             3098..>3564
                     /locus_tag="JAM15_18755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6800287.1"
                     /translation="MSGIISVMTQSLILSIMALGVYITYKILDFPDMSADGSYTMGAS
                     IVAFSLTNGISPVVATLMAILCGCTAGLVTGILHIKFKISNLLSGILVMGMLYSINLR
                     IMGKSNIPLFSFKHLFNGEISPIVLALAFVFICKILLDLFLKTGLGYTLKGVG"
BASE COUNT         1332 a          469 c          543 g         1220 t
ORIGIN      
        1 ctaggtataa atatcggttc tataaaaata ctaggactta tgatttcaaa cggacttata
       61 gctttatctg gtagtcttat ggctcagttc ttgggattct cagatgtaaa tatgggtata
      121 ggaactttag ttcttggaat tgcctctatc ataattggta ttacactatt taagaaattt
      181 acttttatca aagatactac tgcaataatt gttggctctt ttatatacca attcactata
      241 tactttgcaa tgagtttagg aatgttatca actgacttaa aactaataac tgccatagtt
      301 ataatagctt tcctagctac tggtaactta aatatttcac taaaaaaaac aaatgcaaag
      361 ctagtaccaa aaataaatca gaaaaaagag gtgttgtaga tgttacaaat taaaaatctt
      421 tcaaagagtt tccctagtcc atatggtgaa cctaatacta tctttgaaaa tttatcaatc
      481 gatatagaag atggtgaatt tgtaagtatc ataggtagta atggaactgg taaatctact
      541 ttattaaata taatatctgg gcttataaaa gaatcttctg gtcaaattac tttagatagt
      601 actactataa caaatttagc tgagtataaa agaactcaaa tagtaagtag agtttttcaa
      661 gacccaagcc ttggaacttg tccttctatg acggttagag aaaatttatc tctagcactt
      721 aataaaggga aattattgaa cttaaaaaaa tgtcttcgtc ataaaacgaa taatttggaa
      781 cacttacttg aaggaatttc tttggactta aaaaaatatt tagatattaa agtacaatat
      841 ctttcaggag gtcaaagaca atcactatca ctaattatgt ctagcttagc aagtcctaag
      901 gtcttattac tagacgaaca tacagcagca cttgacccaa aaacatcaaa tgaagtaata
      961 gagttaacag ataaaatcgt aagagaaaaa aatataacta cacttatggt tactcacaac
     1021 ttgaaacacg ctcttcaata tggagatagg ttgataatgc ttcataaggg tgaagttgta
     1081 ttagatgtaa aagataaaga aaaagaaaat ttaacagttg aagaaatctt agaaaaattt
     1141 gaatatgcag tataagaaat taaaatctta gttttaatca gaaatattta taatctatca
     1201 tatgaatata tgaacaaata taattattaa attttaaggg aggaaaataa aatgataaaa
     1261 agtaaaaaaa tattaagttt aattatagca ggagtacttg gtgtatcaat gcttactgga
     1321 tgttctcaaa atgatggctc caatgcttca aatgaaaata aaaaaacaga tagcaaaaaa
     1381 caaaaaaata taggtattag tcaattagtg gaacatccgt ctctggataa agcaaagaaa
     1441 ggattcatca aagcactcga agataaaggc tataaagatg gagataatat aaaaatagat
     1501 ttccaaaatg cacaaaatga tatgcctact acacaaagta ttgctagtaa gtttgtatcc
     1561 gacaaaaaag atttgatata tgctatatct actccatctg cacaagcagc ttataatgct
     1621 actaaagata ttccaataat aatgactgct gttacagacc ctgtagaagc tggacttgtt
     1681 aaatctcttg aaaaaccagg tggaaatgtt tctggtacat ctgattatct ttcaattgat
     1741 aaaacattag aattggttaa aacattgact ccaaaagcaa agaaaatagg ggttatatac
     1801 aatactagtg aagttaattc aaaaatccag gttgattctc tacatgatta tgctaagaaa
     1861 aataattatg aagtagttga aaaaggaatc agcacttcaa gtgaagttaa ccaagctatt
     1921 tctagtttag ttggcaaaat agatgtttta tatgtcccta ctgacaattt aatagtttct
     1981 tctatgccaa tagtttctaa agttgctaat gaaaacaaga ttcctataat agcctctgaa
     2041 gaaggttctg tatcttctgg tgctttagct tgttgtggaa tagattatga aaaactaggt
     2101 tataaggctg gagaacttgc tattgaagta ttagaaggaa aatctgttgg cgatatacca
     2161 gttactacat tagatgaaac tgaaataata attaacgaag atacactaaa agcacttgac
     2221 atgcaaaagt tatcagcaga taatataaag tatataaagt cagatgaaaa tgcaaaatct
     2281 gcaaaataaa acttattaat ttcaaaaaat aggtaatatg aagtaggtaa tatgaaaact
     2341 ttatataata agtactctta tccaccctaa ccctttgaaa attgtgctta ttgtagcaat
     2401 ttgaatattg catataaagt tattcatttt ccataaaagt cgtctatatt gacgactgat
     2461 tatgaaagtt atataacttt ctaatcacta cttgagctgt ccaaaagaat tttaatattc
     2521 tccagacagc ttttttttat gatatttgat tgatatacat gtctagttat tccatattta
     2581 gtaaatattt tgataaaatt tccacattca cttataactt aggataacgt tttttgcaaa
     2641 caatacatta atttaaaagt attctgagta tacattattt agtattttaa ttaaatttag
     2701 cagttgactt ttattattgt ataatttata atttataaca agtcgagaat acatataatt
     2761 ttctgactaa ttaaaatatt aaaagggaga gataattatg aatactttat taaacaatag
     2821 aaaatattat tattattata gccactattt ttagggtttg tacctacgtt ttaacataga
     2881 tacagacccc ttaagactac taaaattttg ggattgtatc tatgttggct atattgttta
     2941 taaagttttc atttaactat ataagagcca catagattaa actatgtggc ttattcgtgt
     3001 ttttaccaca tagttttgta cactatgtgg tttttttata cacaaaatta gcaaataatt
     3061 aaaattataa aaatattttc aaaggagtgt tttatttatg tcaggtatta tatctgtaat
     3121 gacgcaaagt ttaattttat cgattatggc actgggggtt tatataactt acaaaatcct
     3181 agattttcca gatatgtctg ctgatggtag ctatacaatg ggtgcttcta ttgtagcatt
     3241 ttctcttact aatggtattt ctcctgtagt agcaacttta atggctatct tatgtggttg
     3301 tactgctggt cttgttacag ggattcttca cattaagttt aagatatcta acttactttc
     3361 tggtatttta gttatgggaa tgctatactc tatcaattta agaataatgg gaaaatcaaa
     3421 tattcctcta tttagcttta aacacttatt caatggggaa atatctccta tagttttagc
     3481 cttagctttt gtattcatct gtaaaatcct tttagattta ttcctaaaaa caggtcttgg
     3541 atacacttta aaaggtgttg gtga
//
LOCUS       DACTZW010000166         3435 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.169, whole genome shotgun sequence.
ACCESSION   DACTZW010000166 DACTZW010000000
VERSION     DACTZW010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3435
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.169"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            106..1704
                     /locus_tag="JAM15_18760"
     CDS             106..1704
                     /locus_tag="JAM15_18760"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative manganese-dependent inorganic
                     diphosphatase"
                     /protein_id="HAT6800288.1"
                     /translation="MSLLVFGHKNPDTDSICSAISLAHLKNKLGIKATAYALGDIRKE
                     AKYALDYFKVDAPKILDNVRIQVRDLNYDKVVPLTPTSSILEAYNLMDEKNVKTLPVT
                     YDDGTFAGIITMKEIAKNLLHQHFTTIHTSLSNICKNLNGTILVDCGEDIKGRVVTLS
                     FGMETLIETLKEGDIAIVGDRYDSIEYAIDTKVKLLILTNHTEISKDLLALAKINGVS
                     VVSVESDNYKTSNVINQCSFLDSIEATENLITFKEDDYMDEIKEIMLETNFRSYPILD
                     DDNKFLGLVSKGHLLNPSKKNVVLVDHNEYAQSADGIEQANIVEIIDHHKLGGISTDV
                     PMSFRVMPVGCNSTIIYKMYKENNVEIPYEIAGLLLSAILSDTLLFKSPTTTDMDKKA
                     CEELSKIAKVDMEKYAMDMFKCGTSLDEYTIEEIVNMDFKEFNMSGHRVGIGQVFTLD
                     IDSIFAKKDEFLSYINSTDYDKLILAVTDIIKEGSYLIYKAEDSLIANAFDVEGVQGT
                     FAPGVVSRKKQLVPNLTTAIKNFK"
     gene            complement(1939..2130)
                     /locus_tag="JAM15_18765"
     CDS             complement(1939..2130)
                     /locus_tag="JAM15_18765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium protein"
                     /protein_id="HAT6800289.1"
                     /translation="MAGLTTEPGGGGVLSGYFAGFLFGGTTFTINNFSSTKVGIRNGQ
                     SAGTAATLTIFRIADTVMT"
     gene            complement(2299..2892)
                     /locus_tag="JAM15_18770"
     CDS             complement(2299..2892)
                     /locus_tag="JAM15_18770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HAT6800290.1"
                     /translation="MRIPDILKDKSILKAELFIHIDSNKNHIFKEKVDIEIKRISEYY
                     NLRTITWNDRVSMENIRGYLPIGISDTSNYICLNITGTIKAWAMNKYPNYGLALSLNY
                     PYQIFEFTSSRDCNKPYILVTFEDRIIDNCYPKCECPPIRITGPMGPRGATGSIGPMG
                     ATGPTGATGNSSQPIANFLVNAPSPQTLNNGNAITGW"
     gene            complement(2893..3039)
                     /locus_tag="JAM15_18775"
     CDS             complement(2893..3039)
                     /locus_tag="JAM15_18775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium protein"
                     /protein_id="HAT6800291.1"
                     /translation="MRKIILYLNDDTFISKKYPDKNFSNLDYCLIGSKCSNSFVKEKL
                     ITFF"
BASE COUNT         1249 a          472 c          460 g         1254 t
ORIGIN      
        1 attttttcac taaatttttt tctttttaca acaaatactc actacctttt gatataatat
       61 ttttatcaat tattattata ttcaagtttt gaaaggagta ttaaaatgag tttattagtt
      121 ttcggacata aaaatccaga tacagattca atatgttctg caatttcatt agcacattta
      181 aagaacaaac taggaataaa agcaacagct tatgctttag gagatatcag aaaagaagct
      241 aaatatgcct tggattactt taaggtagat gcacctaaaa ttttagataa tgttagaata
      301 caagttagag atttaaatta tgataaagta gtacctttaa caccaacttc atctatatta
      361 gaggcttata accttatgga tgaaaaaaat gttaaaacac tacctgtaac ttatgatgat
      421 ggaacttttg ctggtatcat tactatgaaa gaaatagcta aaaatctact tcatcaacac
      481 tttacaacta tacacacatc actatcaaac atttgtaaaa accttaatgg tactattctt
      541 gtggactgtg gtgaagatat aaaaggtaga gtagtcactt tatcatttgg aatggagact
      601 ctaatagaga ctttaaaaga aggagacata gctattgttg gagatagata tgatagtatt
      661 gaatatgcta ttgatacaaa agttaaactt ttaatactta ctaatcatac agagatttca
      721 aaagatttgc tagctcttgc taagataaat ggagtgtctg ttgtttctgt tgaaagtgac
      781 aattataaaa cttctaatgt aataaatcaa tgtagtttct tagactctat agaagctaca
      841 gaaaatttaa ttacattcaa agaagatgat tatatggatg aaataaaaga gattatgcta
      901 gaaacaaact tcagatctta tccaatatta gatgatgata ataagttttt aggtttagtt
      961 tcaaaaggtc atctattaaa cccatctaaa aagaatgttg ttttagttga ccataacgaa
     1021 tatgctcaaa gtgctgatgg aattgaacaa gcaaacatag ttgaaataat tgaccatcat
     1081 aaacttggtg gtatttctac tgatgttcct atgtcattta gagttatgcc tgttggatgc
     1141 aatagtacta taatttataa aatgtacaaa gaaaataatg ttgagatacc ttatgaaata
     1201 gctgggcttc ttttatctgc tatattatca gatacattat tatttaagtc tccaacaaca
     1261 actgatatgg ataagaaagc ttgtgaagaa ttaagtaaaa tagcaaaagt agacatggaa
     1321 aaatacgcta tggatatgtt taaatgcggt acttctttag atgaatatac tatagaagaa
     1381 atagtaaata tggattttaa agaatttaat atgagtgggc atagagttgg tattggacaa
     1441 gtatttacct tagacataga ctctatattt gctaaaaaag atgagttttt atcttatata
     1501 aattcgactg attatgacaa actaattctt gcggttacag atataatcaa agaaggttct
     1561 tatttaatct ataaagcaga agatagctta attgctaacg catttgatgt tgaaggtgtt
     1621 caaggtacat ttgcaccagg tgttgtatca agaaaaaaac aattagtccc taatttaact
     1681 actgcaatca aaaattttaa ataatataaa atttttaaat aacgaaaact gtctcaaata
     1741 tatatttgag acagtttttt attatacata tattgataat aaagttaaat aaaaatccat
     1801 aaatttaaaa tttttatgaa tatattttat tattattgtt attttattca ttctaaaata
     1861 ggtaaaactc aatatataaa aatacttttg tcatttaaat aaaacctaaa tagtttttaa
     1921 gattatttta gacacgtttt aagtcataac agtatcagct attctaaata tcgtcaaagt
     1981 agccgcagtt cctgctgatt gcccatttcg tattcctact tttgtagatg aaaaattatt
     2041 tattgtaaaa gtagtccccc caaataaaaa accagcaaaa tatccagaaa gtactcctcc
     2101 gcctcctggc tcagtagtaa gccctgccaa atcttttcct cctaaaattg ggaataggat
     2161 agcaaaagaa tattgattta tacttgatga acctggttgt aatgctactg aaactgatat
     2221 ataatacaca ccattttctt gtactgtaaa cgtaccattt gcatctactg ttatacttga
     2281 actatttcct attattgttt accaacctgt tatagcattt ccattattta gtgtttgtgg
     2341 agatggtgca tttacgagga agttagcaat tggctgagag gaattgcctg ttgctcctgt
     2401 tggacctgtt gctcccattg gtcctatact tcctgtcgct cctcttggtc ccattggacc
     2461 tgtaattcta attggaggac actcacattt aggataacaa ttatctataa ttctatcttc
     2521 aaatgttaca agtatatacg gtttgttaca atccctacta gatgtaaatt caaaaatctg
     2581 ataagggtaa tttaaagata aagctaaccc ataattagga tatttattca ttgcccatgc
     2641 ttttatagtt cccgtaatat ttaaacaaat atagttggat gtatcactta tcccaattgg
     2701 taaatatccc ctgatatttt ccatagacac tctatcattc catgttatag ttcgtaaatt
     2761 ataatattca cttattcttt taatttcaat atctactttt tctttaaaaa tatgattctt
     2821 atttgaatca atatgaataa ataactctgc ttttaatata cttttgtctt ttaatatatc
     2881 tggtattctc acttaaaaaa aagtaatcaa cttttctttt acaaaactat ttgaacattt
     2941 acttcctatt aagcaataat ctaaattact aaagttttta tctggatatt ttttagatat
     3001 aaaagtatca tcatttaaat aaagtataat ttttctcatt tataatccct ccattttggg
     3061 tctatatcat actatgttta aaatacatgc ttagttacaa tacaattaaa atttatagta
     3121 ttaaattttt atataataat gctgatttct acaaaaaaag aacatgtcat tagaaacttc
     3181 taatagcatg ttctttttca ttattatata ttacacttta aattattcct tgactggctt
     3241 agctggtgta aactaaacca gtctttctaa aatattaagc acttttttct tattatgttt
     3301 tttaggattt attgtctcta ttattgtaaa ccaaagttat aaaattgtaa atagaatata
     3361 ttaccataac aatatttttt tataagtaaa aattataaaa aaccttattt ttattaaata
     3421 gaataaataa aataa
//
LOCUS       DACTZW010000167         3380 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.170, whole genome shotgun sequence.
ACCESSION   DACTZW010000167 DACTZW010000000
VERSION     DACTZW010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3380)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3380)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3380
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.170"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            117..1007
                     /locus_tag="JAM15_18780"
     CDS             117..1007
                     /locus_tag="JAM15_18780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800292.1"
                     /translation="MDWLKNRQLGIGGSDASAVAGLNPWKTSVQVYIEKKEEIPIETK
                     SFRMELGNRLEGLVAELFTEETGLKVRNVNGMLKNEKYPFAIANIDRAIVGEKAFLEC
                     KTTNSFSIKEWENGVPLHYEIQCLHYMAVTGATHCYIAALLGNEKFVWHKINRDNEVI
                     KNLMKIESEFWEENVLKDILPIPDGSDAYSEFLKTRYKNSVKEKIELNLLEDGISKLK
                     RYDDIVLQMKELKGEKQLIEQEIQSEMREFELATLGGRIITWKGATKRSIDTKRLREE
                     MPDIAEKYTNISSYRTFKIK"
     gene            1020..1853
                     /locus_tag="JAM15_18785"
     CDS             1020..1853
                     /locus_tag="JAM15_18785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HAT6800293.1"
                     /translation="MASEKAKGALEKKVSGANTVKVSPSKGMEQLMNKMASQIKKALP
                     SMVSSERFQRVALTAFSNNPRLQSCEPMSFIAAMMESAQLGLEPNTPLGQAYLIPYGN
                     KVQFQIGYKGLLELAQRSGKIKTIYAHKIRENDKFEIKYGLHQDLVHEPKLNGDRGEI
                     IGYYAVYHLDTGGHSFSFMTKEEIIEFAKSKSKSYSSGPWQTDFDSMAKKTVIKQLLK
                     YAPLSIELQKAMVGDETIKSEIDEDMSMVVDESESLEVDFEVKENMDGKVSVEEAINV
                     D"
     gene            1868..2806
                     /locus_tag="JAM15_18790"
     CDS             1868..2806
                     /locus_tag="JAM15_18790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HAT6800294.1"
                     /translation="MNEDKSVIEKLNILSGGYGLMPRIIARDRWLTVGARMLYSYLTS
                     FAGNDGTCFPSRDLICYELDISKDTFTKYKKELEMSGYIRVHKNKSKQGKMQNNIYEI
                     VFDRTYIDECISKRGLKEEKKKKKPCTKKQDTEPYPKNVDMEPCPTFPDTTQPDTENM
                     DTNSNSINSNSINNMYIVKQPVDNFLKEFKKLYEENIGVIYPVTAEWLLEVSNEVDIR
                     VFKRAIEICAEKMNMNLAYLKGILKKWKDANITTYEQLESYRLQQENKKTKKVVNNHV
                     SKNKFANFEQTFTKYSENELDDIIKKSQKEKFGVGS"
     gene            2825..2971
                     /locus_tag="JAM15_18795"
     CDS             2825..2971
                     /locus_tag="JAM15_18795"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800295.1"
                     /translation="MRFEIGKTYKFDKEKFMEINGVEQYKEYKELLMMAMFAIQMNFG
                     LILV"
     gene            3018..3275
                     /locus_tag="JAM15_18800"
     CDS             3018..3275
                     /locus_tag="JAM15_18800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800296.1"
                     /translation="MIIIRSQDRLDLLEVNRVEVDINEVIAIFKGSSDFRKIGEYENE
                     ERAIQVLNEIQKFIESGVRTDYIDSCRVRHNQEKVFEMPVE"
BASE COUNT         1427 a          330 c          700 g          923 t
ORIGIN      
        1 caacacatac aaaaaattca acttatttag gaggatacca taaaatgaat aaaatttcaa
       61 gtcgtagaaa atatttagat gcttttatag taactgatac taagaacata gataaaattg
      121 attggcttaa aaatagacaa ttaggaatag ggggtagtga tgcgtcagca gtagcaggat
      181 taaatccctg gaaaacttct gttcaagtat atatagaaaa gaaagaagaa ataccaatag
      241 aaactaaaag tttcagaatg gaattaggta atagattaga aggattagtt gcagaacttt
      301 ttacagaaga aactggtctt aaggtccgta atgtaaatgg aatgttgaaa aatgaaaagt
      361 atccttttgc aatagctaat atagacagag ctatagtagg agaaaaagca tttttagaat
      421 gtaagacaac aaatagtttt tctataaaag aatgggaaaa tggagttcca cttcattatg
      481 aaatacaatg cttgcattat atggctgtca caggagctac acattgttat atagcagcac
      541 ttcttggaaa tgaaaagttt gtatggcaca agataaatag ggataatgaa gtaattaaaa
      601 atctaatgaa aatagagagt gaattttggg aagaaaatgt attaaaagac attttaccaa
      661 ttcctgatgg ttcagatgct tatagtgagt ttctgaaaac aaggtataaa aactcagtaa
      721 aagagaaaat agaactaaat ctacttgaag atggtatatc aaagttaaaa agatatgatg
      781 atatagtttt acaaatgaaa gaactaaaag gagagaaaca gctaatagaa caagaaatac
      841 aaagtgaaat gagagagttt gagttagcta cattaggcgg aagaataata acttggaaag
      901 gagctactaa aaggtccatt gataccaaga gattaagaga agaaatgcct gatatagcag
      961 aaaaatatac aaatataagt tcatacagaa cattcaaaat aaaatagggg gtaatatata
     1021 tggctagtga aaaagcaaaa ggagcattag aaaagaaagt ttcaggagca aatacagtca
     1081 aggtaagtcc aagtaaaggt atggagcaac ttatgaataa aatggcaagt cagataaaaa
     1141 aagctttacc tagtatggtt tcaagcgaga gatttcaaag agttgcccta acagctttta
     1201 gtaataatcc aaggttacaa tcatgtgaac ctatgagttt tatagcagca atgatggaat
     1261 cagctcaatt aggtcttgag cctaatacgc ctttaggtca agcatatttg ataccatatg
     1321 gaaataaagt gcaattccaa attgggtata aaggtctttt agaattagca caaagaagtg
     1381 gaaagataaa aactatatat gctcataaaa taagagaaaa cgataaattt gagattaaat
     1441 atgggcttca tcaagactta gttcatgaac ctaaattaaa tggtgataga ggggaaataa
     1501 ttggatatta tgcagtatat catttggata caggaggaca tagtttttct tttatgacta
     1561 aagaggaaat tatagaattt gcaaagagta aaagtaaaag ttatagtagt ggaccatggc
     1621 aaacagattt tgattcaatg gctaaaaaga cagttataaa acagttatta aaatatgcac
     1681 cacttagtat agaattacaa aaagctatgg taggtgatga aacaataaaa tctgaaatag
     1741 atgaagatat gagcatggtc gtagatgaaa gcgaaagttt agaagttgat ttcgaagtaa
     1801 aagaaaatat ggatggtaaa gttagtgtgg aagaagctat aaatgttgat taagtaggtg
     1861 aggcaccttg aatgaagata agtcagttat agagaaatta aatatattaa gtggtggata
     1921 cggtcttatg ccaagaataa tagcaagaga taggtggttg acagttggtg ctagaatgct
     1981 gtattcatat ctaactagtt ttgcagggaa tgatggaaca tgttttccat ctagggattt
     2041 aatttgttat gaactagata tatcaaaaga cacatttaca aagtacaaaa aagagctaga
     2101 gatgagtggc tatataaggg ttcataagaa taaatccaaa caaggcaaga tgcaaaacaa
     2161 tatatatgaa atagtatttg atagaactta tatagatgaa tgtatttcta agagaggttt
     2221 aaaagaggag aaaaagaaga aaaagccatg tactaaaaag caagacacgg aaccgtatcc
     2281 taaaaatgta gacatggaac catgtcctac ttttccggac acgactcagc cggacacgga
     2341 aaatatggac actaatagta acagtattaa tagtaacagt attaataata tgtatatagt
     2401 aaagcaacct gtggataact ttttaaaaga atttaagaag ctgtatgaag aaaatatagg
     2461 agtaatatat ccagttacag ctgaatggtt attagaagta tctaatgaag tagatataag
     2521 agtatttaaa agagctatag agatatgtgc tgaaaagatg aatatgaatc tagcatactt
     2581 aaaaggtatc cttaaaaaat ggaaggatgc aaatattact acatatgagc aactggaatc
     2641 atatagatta cagcaagaaa ataagaaaac aaaaaaagta gttaataacc atgtgagtaa
     2701 aaataagttt gctaactttg aacaaacatt tactaagtat tcagaaaatg aacttgatga
     2761 cattattaag aaaagccaaa aagagaagtt tggagtagga agttaaaata ttggagggat
     2821 agaaatgaga tttgagatag gtaagactta taagtttgat aaagagaaat ttatggaaat
     2881 taatggtgta gaacaatata aagaatataa agaacttttg atgatggcta tgtttgctat
     2941 ccaaatgaat ttcggtttaa ttttggtgta atttcggaat ggtgtgttga agttaaataa
     3001 ggtagggggt attagagatg ataataatta gaagtcaaga tagattagat ttattggaag
     3061 ttaacagagt tgaagtagat ataaatgagg taatagctat atttaaaggt agttcagatt
     3121 ttagaaaaat aggtgaatat gagaatgaag aaagagctat acaagtgtta aatgaaatac
     3181 aaaagtttat tgaaagtgga gtaagaactg attatataga ttcttgcaga gttagacata
     3241 atcaagagaa agtatttgaa atgccagttg aataaaaggg ggatgggaca tggctaaagt
     3301 ttggatagat gcaggaacat ttttagaaac taaagatata ggagatattg aatgtaatct
     3361 aagagaaatg ataaataaaa
//
LOCUS       DACTZW010000168         3331 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.171, whole genome shotgun sequence.
ACCESSION   DACTZW010000168 DACTZW010000000
VERSION     DACTZW010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3331)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3331)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3331
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.171"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     regulatory      <1..84
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            167..652
                     /locus_tag="JAM15_18805"
     CDS             167..652
                     /locus_tag="JAM15_18805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HAT6800297.1"
                     /translation="MISELMLKNFGKSSINFKTKIKLNLREKPDINSLKLKSIPEGKI
                     VKLKCVDGIWAEVESNYDKGWLLYKYLERLSNAKNNSNDTIKNRKKNYIGNIRTNGLS
                     LELRNDRTLESKVITTIPDGFKVEVCYSVGKWARVNINKNEKRYSGYVYNQYIEEHLS
                     L"
     gene            1008..1406
                     /locus_tag="JAM15_18810"
     CDS             1008..1406
                     /locus_tag="JAM15_18810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800298.1"
                     /translation="MNKKKKLIGIAISFLLIISIINPLQVEAEAIIESSVYISSIKEN
                     YTYDNTKFKTIKSKSRHKSRKYNKSKVKLKKRSIRTKKYGYQTINKYKRRNARRHNIL
                     TKLVLSIIVIFLVIVLVVLIFIKRKKKKFY"
     misc_binding    1842..2105
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            2256..2807
                     /locus_tag="JAM15_18815"
     CDS             2256..2807
                     /locus_tag="JAM15_18815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan transporter"
                     /protein_id="HAT6800299.1"
                     /translation="MKTNTKKLTLNAILLAMGLLIHQITPAIGLPMKPDVPLAMLFVI
                     LVLNRDDYKTCLIAGIVTGIFTALTSSFPGGQIPNVIDKTLTANIVFLLMNISYNMPF
                     IKKLAKKTQDTVVVAIIMPIGTLVSGTIFLLAAQAIVGLPGASFTALFLAVVLPAVLI
                     NLVAGIFLFKIVSLSIRRVSYQA"
BASE COUNT         1432 a          294 c          472 g         1133 t
ORIGIN      
        1 ggcaatatta gataaatcta atgacgcaaa actataggga ctaaaatctt tatgtaataa
       61 aggtcatgtc agccagttgc caaaaagata ataattcttt ttgttaaaag tatttttaga
      121 gttatatatt ttaataactt aatatttggc aagaggaggg cttaagatga tatctgaatt
      181 aatgttaaaa aattttggca aatctagcat caattttaaa actaaaatta aattgaattt
      241 aagagaaaaa ccagacataa atagtttgaa attaaaaagt ataccagaag gtaaaattgt
      301 taagttaaaa tgtgtagatg gaatatgggc agaagttgag agtaattatg acaaaggctg
      361 gttactttat aaatatttag aaagattaag taatgctaaa aacaatagta atgatacaat
      421 aaaaaataga aaaaagaatt acataggaaa tataagaaca aatggattaa gtttagaact
      481 tagaaatgat agaacattag aatctaaagt tataactaca atccctgatg gttttaaagt
      541 tgaagtatgt tatagcgttg gaaaatgggc aagagttaat atcaataaaa atgaaaaacg
      601 atattctgga tatgtatata atcaatacat agaagagcat ttaagtttat aatacgatac
      661 tagtgagctt taaatatgtt aataaatcac aaaaaagaat cccattaatg ggattctttt
      721 ttgtagaaac attataacag aactaaagag aataaattaa ctaatttatt tttattataa
      781 agtaattata aatggtaaat ttaattgaaa gtagatttaa cttatacttt atacaccaag
      841 tatcataaat taatgctact ttgaaaaatt ttaaaaaaag taaaagttat gataataaaa
      901 ataatattaa agataataag atatataaga aacttgaaaa aatttgtaat ttttagttat
      961 atatatatta taatgaacta gttaaaaatt tttatgaggg ggaaaatatg aataagaaga
     1021 aaaaattgat tgggatagct atatcttttc tacttataat cagtattata aatccattac
     1081 aagtagaagc agaagctatt attgagtcta gtgtatacat ttcttcaata aaagagaatt
     1141 atacatatga taatactaaa tttaaaacta ttaaatctaa aagtagacat aaaagtagga
     1201 aatataataa aagtaaagta aagttgaaaa aacgaagtat aagaactaaa aagtatggat
     1261 atcaaactat aaataaatat aaaagacgaa atgcaagaag acataatatc ctaacaaaat
     1321 tagtattgtc cataatagtc atatttttgg ttatagtttt agtagtgcta atatttatta
     1381 aaagaaagaa gaaaaaattt tactaaaaat aattaaaaga atatcatttt tctaatcatt
     1441 ggtatctatt taataatatg atgtaattaa aatggagtaa tattctgttt caaaggaggc
     1501 atataaatac aggaatgagt attaaatgat ggttaattaa gtaaatttat tgataaatgt
     1561 acttaattaa ctttgaagaa tttaattcct catgaatcaa aatataaaat tacatcaaca
     1621 gttattcaca aaattaatat aagaagaatt agagccaaag agcagactat tagaccatta
     1681 aagtaattat tcatagaatt ttgtatatga aaagaaatgt atagtataat ttactttttt
     1741 tataaaaaat agattacaaa atatattttt tataaaaagg tattgacatt ttttagaaaa
     1801 aagaatatca ttattttaac aacaaaattc aatacaataa attaaatcct atgacaagga
     1861 agagtagtta aatttaggtt cagtatagag agctgaggat ggtggaatct tagcaagaaa
     1921 aaatttgatg aatggccctt agaggaataa attgaaatca tagttttgag agtagacttt
     1981 atcgtcagtc gcacgttata gcgaataagg tatgtaagta cctgataatg agatgtatga
     2041 aaattgaatt ttatattaat ttttatataa tttaggtggc aacgcggata atctccgtcc
     2101 tattatttta ggacggagtt ttttatttta ctgaaaattt aaaagataga aggtggtgag
     2161 aaagatgtta tgaatttcaa aagctaaaga tgatgatata gtaggttggc aaaaaaataa
     2221 attgaaaatt aaaaaaatag gaggaagtac aaaaaatgaa aacaaataca aaaaaattaa
     2281 ctttaaatgc aatactttta gcgatgggat tattaataca tcaaatcaca ccagctatag
     2341 gattaccaat gaagccagat gtaccactag caatgttatt tgtaatattg gttttaaata
     2401 gagatgatta taaaacttgt ttgatagcgg gtatagtaac aggaatattt acagcactta
     2461 catcaagttt tccgggaggt caaattccta atgtaataga taaaactctt acagcaaata
     2521 tagtattttt attaatgaat attagttata atatgccttt tataaaaaaa ttagctaaga
     2581 aaacacaaga tactgtagta gttgcaataa taatgccaat aggaactctt gtaagtggaa
     2641 ctatcttttt attagcagct caagctatag ttggtcttcc aggggcttca tttacagctt
     2701 tattcttagc agtagtatta ccagctgttt taataaatct agttgcagga atatttttat
     2761 tcaagattgt tagtctatca ataagaagag ttagttatca agcttaacta cgaaataata
     2821 ttttacttta taaagcatta taataactaa ataacataag aataaagtag attataacta
     2881 ttttattctt atgttgttta aagatttggt attatatatt tatttttaat aaaatattta
     2941 tatagtacaa attacactta attcaacaga taaattatca tacctatata atattcttat
     3001 atgtatctca tttgtagtta ttaaatataa gatatattta attgactttt caagataaat
     3061 ttttatatta atctcctctg atttctcatt ttttgaatac actaaaattt ccaattaaat
     3121 caattatata tttataaagt tttaaaaata tagtaatgta tatatttttt gtgaaaaact
     3181 tgcttaaatt tagccaaaaa aaatagataa ttcatagtaa aaaataaagt ttagtaaaaa
     3241 attttaatag aactataaaa gtctgtttta gtaaaagatt taaaattcta atattaagtg
     3301 aaattttggg tgaattaaat aagcgaaact a
//
LOCUS       DACTZW010000169         3152 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.172, whole genome shotgun sequence.
ACCESSION   DACTZW010000169 DACTZW010000000
VERSION     DACTZW010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3152)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3152)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3152
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.172"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(300..557)
                     /locus_tag="JAM15_18820"
     CDS             complement(300..557)
                     /locus_tag="JAM15_18820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAT6800300.1"
                     /translation="MKIKVEDIPVQFHAMVEIIGIDKFIEVAKLYGGTNTYIPTYKGL
                     FRYARNRDIVKQFNGVNHNELAIRYNMCVSNIKRILNENNV"
     gene            1137..1358
                     /locus_tag="JAM15_18825"
     CDS             1137..1358
                     /locus_tag="JAM15_18825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1659 domain-containing protein"
                     /protein_id="HAT6800301.1"
                     /translation="MEVVSTKNLSSIKLKLDAGFDDKGKAVVKSKSFANVKAEALNED
                     VYAVAEAIASLQENPIVDILKLDSTSLSK"
     gene            2014..2244
                     /locus_tag="JAM15_18830"
     CDS             2014..2244
                     /locus_tag="JAM15_18830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2922 domain-containing protein"
                     /protein_id="HAT6800302.1"
                     /translation="MEIKKKLVMSFKNVKDKQVSFSIENPKDDLTEENIKSVMDLIVS
                     KNIFSVGGFDLASVVEAKVVETNTTPYDLVIE"
     gene            2257..2406
                     /locus_tag="JAM15_18835"
     CDS             2257..2406
                     /locus_tag="JAM15_18835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvrJ family protein"
                     /protein_id="HAT6800303.1"
                     /translation="MDDSLQLLITNVGFPIALSMYLLVRIEGKLNTLSNSIDTLSKNI
                     LIFKK"
     gene            2663..3100
                     /locus_tag="JAM15_18840"
     CDS             2663..3100
                     /locus_tag="JAM15_18840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator"
                     /protein_id="HAT6800304.1"
                     /translation="MKIHVEQGINCDDIEITIKCSALDNNIEKIISLLSTPLLDIKGK
                     KSGEIYKLNVCDILYFETVGNKTFAYYEDDVFEIDLKIYKLSKLLANTSFSRISKSMI
                     LNMDYIKSIKVISHNRMQATLKNNEKVIINRRYIKNIKEKLNI"
BASE COUNT         1263 a          399 c          335 g         1155 t
ORIGIN      
        1 aattttataa atatattatg tcatattaat tgctatttct ttatttatat agtttattta
       61 tttatttttc ccctttatac aagcaattgt atcattttat ctatttttta gccaacaaat
      121 attttcgacc attttctttg tattctcaat atatctccag tatttaacaa atttttttat
      181 agaatataca atgtatttaa attaataagt agtaaattta gttaatttgt ctaaaaaaac
      241 tttataaaac atcttctttg tctttactct tacatttaac aaggctattt tcattatgtt
      301 taaacattat tttcattgag tattcgctta atattgctta cacacatatt atatctaata
      361 gccaattcat tatggttgac tccattaaat tgttttacta tatccctatt tctagcatat
      421 ctaaaaagcc ccttatacgt aggtatataa gtatttgttc ctccatacaa cttggcaacc
      481 tctatgaact tatcaattcc gattatttct accattgcat gaaattgaac tggtatatcc
      541 tccactttta tcttcataag ttacacctcc tttaagatat ttttatagac ttaacaaagt
      601 ttttatttaa tacattattg actaaactat atttattagt tttattgaat ctaataaaaa
      661 atttcttagc tttaaaatta atttttgtat taactttaat aaaatttctc ataacttata
      721 actttgttag ctttaataaa gattttaatg gtttaaaagt aaaatgttaa tattggactt
      781 ttaacttttt tatttacaga ttaaatttaa taaaattttt aacataagct ttaacattta
      841 atttaacata aactttggta cctaacattt aactctacac atatgaaaat ccatacaaaa
      901 ctatctcaac taagcatgaa tatatacaaa tactatttca aaacactaag aacatatctt
      961 caaaaataac ttgtaaactt tttcatcatc agaaaagtaa aatttttcct ataaaaattt
     1021 acacaaaaaa tctttagaaa ttactgttta actccgatat tatcttagat gatagtatta
     1081 tagctaacaa agaaagtcga caaatctttg aaattaaatt tttaggaggt aattttatgg
     1141 aagttgtttc aacaaaaaat ttatctagta taaaactaaa attggatgct ggttttgatg
     1201 ataagggtaa ggcagttgtt aaaagtaaat catttgcaaa tgtaaaagca gaggcattaa
     1261 atgaagatgt ttatgctgtt gcagaagcaa tagcaagtct tcaagagaac cctattgtag
     1321 atattttaaa attagatagt acatcattat ctaaatagta tcttttaaac gtactctgct
     1381 ttacaaatta aaaaaattaa ctctttatat aaaagattaa gttatataac gcacttaata
     1441 cgctatagat ttggcagatt ataacttcaa ttttggttat aactttaata tattaatgct
     1501 ttgaaaaatt aatatattaa acgtatttca acttaaacat gttagctatt ttaaatgcta
     1561 ccctacttta atctaattaa ttgaaataaa ttaaatattt tctatatcag caataactag
     1621 agtcaacaat taaaatacta atattgacaa ttgaaacact gatactaaca aacaaaacac
     1681 taatattgac aattgaaata ctaatactaa tactaacaag caaaacacta atattgacaa
     1741 ttgaaatact aatactaaca agcaaaacac taatattgac aattgaaata ctaatactaa
     1801 caagcaaaac actaatattg acaattgaaa tattaatact aacaagcaaa acattaatat
     1861 tgacaattga aatactaata ctaacaagca aaacattaat attgacaatt gaaatattaa
     1921 tactaacaag caaaacacta atattgacaa ttaaaatacc aatattaaca agcaaacaat
     1981 taaaatataa attattatat cggaggtaat tatatggaaa ttaagaaaaa attagtcatg
     2041 agctttaaaa atgtaaagga taaacaagtt tctttttcta tagaaaatcc aaaggatgat
     2101 ttaactgaag aaaatataaa atctgtcatg gatttgatag tatctaaaaa tattttttcg
     2161 gttggaggat ttgacctagc ttctgttgtt gaagccaagg ttgtggaaac aaataccact
     2221 ccttatgact tagttataga ataggaggct aattttatgg atgatagttt acaactgtta
     2281 ataaccaatg ttggttttcc tatagctcta tccatgtact tgttggttag aattgagggt
     2341 aaattaaata ctttatcaaa cagtattgat acattatcca aaaacatttt gatatttaag
     2401 aagtaatttg acaatatatg taagtcataa aataggtcta tttgtaaaat aattagacat
     2461 attctatgct aaatactagg atatttggat aatttatcca aatatccata gtattttttt
     2521 gaattttacc acctcaaatt tgaatttcac tattttattt ttgaatttca ctatgcttaa
     2581 tttgaaattt agaacgcatc tagttggact caataagata taatgctatt ctaatgacag
     2641 taataaaatg aggtgatgat taatgaaaat acatgtcgaa caaggtatta attgtgatga
     2701 tattgaaata accataaaat gttctgctct agataataac attgaaaaaa taatttcatt
     2761 attgagtaca ccattacttg atataaaagg taaaaaatca ggagagattt ataaactcaa
     2821 tgtctgtgat attttatact ttgaaacagt tggaaataaa acatttgctt attatgaaga
     2881 tgatgtattt gaaattgatt taaaaatata taaattatca aaattattag ctaatacatc
     2941 cttctcacga atatctaaat ccatgatttt aaatatggac tacataaaaa gtataaaagt
     3001 aatatcacat aatcgcatgc aagctacttt aaaaaacaac gaaaaagtta ttataaatcg
     3061 tcgttatata aaaaatatta aagaaaagct aaacatttaa taaaaatcta aagtaattta
     3121 ttaatatcac taattgcaaa tttattgacc ta
//
LOCUS       DACTZW010000170         2863 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.173, whole genome shotgun sequence.
ACCESSION   DACTZW010000170 DACTZW010000000
VERSION     DACTZW010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2863
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.173"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            <1..1557
                     /locus_tag="JAM15_18845"
     CDS             <1..1557
                     /locus_tag="JAM15_18845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAT6800305.1"
                     /translation="FIINIFQPLIFAIAGAGILKSLLMLLAMFNILKSDSTIYTLLVA
                     ISDATFYFLPLMVAVTTANVLKCNRLVAIAAVGYLLLPATTTALSEGVELFGFTIPNI
                     AYNAQVFPAILCVSFLATMEKIFNKYSPKPIRTFFVPMMSLAITVPITLTILGPLGYN
                     VGTIFTTIILFLYNKMGFLVVGLLAAFLPFMVATGMHKALIPYSINTIGKLGYEALYM
                     TSSLAHNISESGACFAVALRTKDETLKQTALSAGISALMGITEPALYGITLQHKRAML
                     GVVFSSAISGTFLGLFAVKGFVIVGPGLASMSMFIDPNNGNNLIFASIGFVIAILGSF
                     IITLIIWKEDTNTVESSIGDVVEEELEEEKEVNILVTPVEGKVIDLSKVNDELFASKT
                     LGDGVAIIPTNGNLYAPCDSEVVMLFETKHAIGLRTKNGAEILIHIGINTVSMNGDGF
                     KTFVKTGDNVKEGDLLIQFDLEKISHANLDSTVMIVNNNGADYAYKVLNQSYGNVKKG
                     SILFDVKGGI"
     gene            1560..>2863
                     /locus_tag="JAM15_18850"
     CDS             1560..>2863
                     /locus_tag="JAM15_18850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008690640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAT6800306.1"
                     /translation="MRKFPEGFLWGGATAANQFEGGWNLGGKGWSVSDVAKAHFDADV
                     KDYKSNNEITTKDIEEGLAHPEDEVNYPKRHGSDFYHHYKEDIALMAEMGFKTYRMSI
                     AWSRIFPNGDDKEPNEEGLQFYDDVFDELISYGIEPLVTMSHYEPPLNIVLNYDGWYS
                     RQVINMFVRYVETICERYKNKVKYWLTFNEVDSMIRHPYTTGGLVRDRFKDKNFEEVI
                     FQAMHHQFVASALATKICHEIIPNSKVGCMLTKLTYYPYTCRPEDVLATQQKMRSIYA
                     YSDTQVFGEYPVYLLSYFKNNNIQIAKEEHDDEIMKKYPVDFISFSYYMSSCEAADTT
                     GLDITPGNTLLAVKNPYLEMSEWGWQIDSIGLRISLIELYDRYRKPLFIVENGLGAKD
                     ILTEDKKVHDQYRINYLKEHFKCMLDAIIEDGVELWGYTSWG"
BASE COUNT          980 a          365 c          550 g          968 t
ORIGIN      
        1 tttattatta atatttttca accactgatt tttgctattg caggagctgg tattttaaaa
       61 tcactgttga tgttattagc aatgtttaat attttaaaat cagattctac tatatataca
      121 ttattagttg ctatttcaga tgcaacattc tatttcctac ctcttatggt agctgtaact
      181 actgccaatg tattgaagtg taatcgttta gtagctattg ccgctgtagg atacttattg
      241 cttccagcaa caacaactgc tttaagtgaa ggggtcgaac tatttggatt tacaattcca
      301 aacattgcct ataatgcaca agttttcccg gctatcttat gtgtgtcttt tttggcaaca
      361 atggagaaaa tttttaacaa gtattcacca aaaccaattc gaactttctt tgttcctatg
      421 atgtctttgg caattactgt tccaattact ctaactattt taggtccttt aggatataac
      481 gttggtacaa tttttacaac cattatttta ttcttatata acaaaatggg attcttagtt
      541 gtaggattac ttgctgcttt tcttccattt atggttgcaa caggaatgca caaagcacta
      601 ataccttatt caattaatac aattggaaag ttgggttatg aagctttata tatgacatct
      661 tcattagccc acaatatttc tgaaagtggt gcttgttttg cagtagcctt gcgaacaaaa
      721 gatgaaacat taaaacaaac agcattatct gcaggaattt ctgccttgat gggaattaca
      781 gagccagctt tatatggtat tactttacaa cataaaagag caatgttagg tgttgtattc
      841 tcaagtgcaa tttctggtac atttttagga ttatttgcag taaaaggatt tgtaattgtt
      901 ggaccagggc ttgccagtat gagtatgttt attgacccaa acaatggaaa caatttgatt
      961 tttgcgagta ttggttttgt tattgcaata ttaggctcgt ttattattac actgattatt
     1021 tggaaggaag atacaaatac agtagagtca tcaattggag atgttgttga agaagagcta
     1081 gaagaagaaa aagaagtaaa tatcttagta actccagtag aaggaaaagt aatagattta
     1141 agtaaggtta atgatgaact atttgcaagt aagactttgg gagatggagt tgcaattata
     1201 ccgaccaatg gaaatttata cgcaccttgt gattcagaag ttgtgatgtt atttgaaaca
     1261 aaacatgcaa ttggtttaag aacaaaaaat ggggccgaga ttttgattca tattggaata
     1321 aatactgtaa gtatgaatgg agatggattt aaaacatttg ttaagacagg cgataatgta
     1381 aaagaaggag atttattaat tcaatttgat ttagaaaaaa tctcacatgc taatttagat
     1441 tcaactgtta tgattgtaaa caataatgga gcagattatg cttataaagt gttaaaccag
     1501 tcttatggca atgtaaaaaa aggaagtatc ttgtttgatg taaagggagg aatataaata
     1561 tgagaaagtt tccagaagga tttctttggg gaggagctac agctgctaat caatttgaag
     1621 gtggttggaa tttaggtggt aaagggtggt ctgtatcaga tgtagcaaag gcacactttg
     1681 atgcagatgt gaaagactat aaatctaata atgaaatcac aacaaaagat atagaagaag
     1741 gattagcaca tcctgaagat gaagtaaatt atccaaaacg tcatggtagt gatttttatc
     1801 atcactataa agaagatatt gctctaatgg cagaaatggg atttaagaca tatcgaatga
     1861 gtattgcttg gtctcgtatt tttccaaatg gagatgataa agagccaaat gaagaaggtt
     1921 tacagtttta tgatgatgta tttgatgagt tgataagtta tggaattgaa ccacttgtta
     1981 ctatgtcaca ttatgaacca ccattaaata tcgttttaaa ctatgatgga tggtattcac
     2041 gacaagttat caatatgttt gttaggtatg tagaaactat ctgtgaaaga tataaaaaca
     2101 aagtgaaata ttggcttaca tttaatgaag ttgattctat gattcgtcat ccgtacacta
     2161 ctggtggttt agttcgagac cgttttaagg ataaaaactt tgaggaagtt atttttcaag
     2221 ctatgcatca tcaatttgta gctagtgccc ttgcaacaaa aatttgccat gagattattc
     2281 caaattcaaa agtagggtgt atgttaacaa aattaacgta ttatccatat acatgtagac
     2341 cagaagatgt tttggcaact caacaaaaaa tgagaagtat ttatgcatat agtgatacgc
     2401 aggtttttgg tgagtatcca gtatatttac tttcgtattt taaaaataat aacattcaaa
     2461 tagcaaaaga agaacatgat gatgaaatta tgaaaaagta tccagtagat tttatttcat
     2521 tctcttacta tatgtcttct tgtgaggcag ctgatacaac tggattagat attacacctg
     2581 ggaatacgtt attagctgta aaaaatcctt atttagaaat gagtgaatgg ggttggcaaa
     2641 ttgattcaat aggtctacgt atatctttga ttgaattata tgatagatac agaaagcctt
     2701 tatttatagt tgaaaatgga ttaggagcca aagatatttt aactgaagat aaaaaagttc
     2761 atgaccaata tagaattaat tatttaaaag aacactttaa atgtatgtta gatgcgatta
     2821 tcgaagatgg cgttgaactt tggggataca cttcatgggg ttg
//
LOCUS       DACTZW010000171         2756 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.174, whole genome shotgun sequence.
ACCESSION   DACTZW010000171 DACTZW010000000
VERSION     DACTZW010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2756)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2756)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2756
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.174"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(23..595)
                     /gene="mobB"
                     /locus_tag="JAM15_18855"
     CDS             complement(23..595)
                     /gene="mobB"
                     /locus_tag="JAM15_18855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HAT6800307.1"
                     /translation="MLLLDSFMKGHNFMYNILSVVSYSGVGKTTLIEGIIKELNKKGY
                     RVGVIKHTCHDFDMDEEGKDTYKHRKSGARKVCIISDKRVAYIEELKEKNPLYKMIQL
                     YEDMDLIIIEGYKNYRFKRLEVTRKGKYEDILSNKSDLIGIVSDIEYKLNIEQFNLND
                     YKNISKYIESCIKNEILSISNVEIKNILKE"
     gene            complement(579..1760)
                     /locus_tag="JAM15_18860"
     CDS             complement(579..1760)
                     /locus_tag="JAM15_18860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HAT6800308.1"
                     /translation="MIELEDAIKIIEKNVLPINRVKIVNLIDAVNKVVAEDIYSTIDS
                     PPFDRSPYDGYAYNANSENRNLKVIGTLYAGDVFNRVLNKNEAVKIMTGGKIPQGANC
                     VIKKEDVTVIGDMITLNIKLKEYDNYIFKGEDIKKGQLIINKNQNIGYDGIGVLASLG
                     ISKVTVYDDLKVGILNTGTELQDINETLENGKIYDSNRYTLYSRLLKLGIQADTICNC
                     SDDILELEKKVKNMLQSVDFLITTGGVSVGDKDLIPDVFKKIGATELFWKINIKPGGA
                     CYVGTLGEKLLFGLSGNPHAAIVVFDNVIVPVIEYLTYKKGTHHIKAIFKGEFNKLSN
                     KDRFVSGKLYTSEGKLYVELNDKKDAKARLSATLRSNCMIKIKKNETIKENQLVDVVI
                     R"
     gene            complement(1971..2705)
                     /locus_tag="JAM15_18865"
     CDS             complement(1971..2705)
                     /locus_tag="JAM15_18865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800309.1"
                     /translation="MKLKRSLVCVTILGIILVGCHKENTKEKNQVASKATQQKTMTKV
                     QNDVNEIMNKDYKYIIKNMGIPYNTFYYIKPKVLKESNTMQDINTSSYMTLVYPKYTG
                     NDELDGSALYVDINENKVVNVETNSFSSQGISVIDAESNVVIEKSDHEKSAVSLENFR
                     RIDLGEYVGVEESRINEIVGDANYDLTAYNHEGSKVVKSYRLKEDNKILKKEVLTISI
                     VDNKIKSIKTIESDKIVKIIKGTLLE"
BASE COUNT          861 a          497 c          224 g         1174 t
ORIGIN      
        1 atataagaag aacatcttaa aattattctt ttaatatgtt ttttatttca acattgctta
       61 tacttaaaat ttcatttttt atacaagact ctatgtactt tgatatattt ttataatcat
      121 ttaaattaaa ctgttcaata ttcaatttat attctatatc actgacaata cctatcaaat
      181 cagacttatt agataaaata tcctcatact taccttttct agttacttcc aatcttttaa
      241 atctataatt tttatatcct tctatgataa tcaagtccat atcttcatat aattgaatca
      301 ttttatataa tggattcttc tcttttagtt cttcaatata tgctactcgt ttatctgata
      361 ttatacagac ttttctcgcc ccagattttc tatgtttata agtatctttt ccttcctcat
      421 ccatatcaaa atcatggcag gtatgtttaa taactccaac acgataccct tttttattta
      481 attcttttat tatgccttca atcaacgtag ttttacctac tcctgaatat gagacaactg
      541 acaatatatt atacataaaa ttgtgtcctt tcataaaact atctaataac aacatccact
      601 aattgatttt cttttattgt ctcattcttt ttaatcttaa tcatacaatt acttcttaga
      661 gttgcagata atctagcttt tgcatctttc ttatcattta gctctacata caatttacct
      721 tcacttgtat atagttttcc acttacaaat ctatctttat ttgaaagttt attaaattct
      781 cctttaaata tagcttttat atgatgtgtt cccttcttat atgttaaata ctcaataaca
      841 ggaactatca cattatcaaa taccactatt gctgcatgtg gattaccaga aagaccaaat
      901 aatagctttt ctcccaatgt acctacataa caagctccac caggtttaat gtttatcttc
      961 caaaataatt ctgttgcccc tatttttttg aatacatctg gaattaaatc tttatctcca
     1021 acagaaacac cacctgtggt aattaaaaaa tctacactct gtaacatatt ctttaccttt
     1081 ttttctaact ccaatatatc atcagaacaa ttgcatattg tatctgcttg tattccaagt
     1141 tttaataatc ttgaatataa ggtatatcta ttactatcgt atattttacc attctctaaa
     1201 gtctcattta tatcttgtag ttctgtacct gtattcaaaa ttccaacttt taaatcatca
     1261 taaacagtta ctttggatat tccaagactt gctaatactc caataccatc atatcctata
     1321 ttctgatttt tattaataat caattgcccc ttttttatat cctcaccctt aaatatgtaa
     1381 ttatcgtatt cctttaattt tatatttaaa gttatcatat cacctataac tgttacatct
     1441 tcttttttta ttacacaatt tgcaccctgt ggtatctttc caccagtcat tatcttcact
     1501 gcttcatttt tatttaatac cctattaaat acatctcctg catacaaagt ccctataacc
     1561 tttaaatttc tattttcaga atttgcatta tatgcataac catcataggg tgacctatca
     1621 aatggaggac tatcaattgt tgaatatata tcttctgcaa ctaccttatt tactgcatct
     1681 ataagattta ctatcttgac cctgtttatt ggtaaaacat ttttttcaat aatttttatg
     1741 gcatcttcta attctatcat tttaaatact ccccaatata ttttttattt aagatatttc
     1801 tatgtaatat attatagatt ataaaagttg gaaatacttt tatcttatat ttaattataa
     1861 ctaatagtta tctataagtg cagttcaaat tttataaatc taataaaaaa actgttccca
     1921 gctagaaatt tccttctatc ttgaaacagc atcatatgct ttagaatatt ttattctaat
     1981 aaagttcctt ttattatttt tacaatttta tcactttcaa tagtttttat agattttatt
     2041 ttgttatcca caatacttat tgtaagtacc tcttttttta atattttgtt atcttctttc
     2101 aatctataac tcttaactac tttactgcct tcatgattat atgctgttaa atcataattc
     2161 gcatctccta caatttcatt tattctagac tcttcaacac caacatactc tcccaggtca
     2221 atacgtctaa aattttctag tgatacagcc gatttttcat ggtcactttt ttcaatcaca
     2281 acattagatt cagcatcaat gactgatata ccttgtgatg agaaagaatt ggtttcaaca
     2341 ttgacaactt tattttcgtt aatatcaaca tataaagcac ttccatctag ttcatcattt
     2401 ccagtatatt ttggataaac taatgtcata taacttgatg tatttatatc ttgcattgta
     2461 ttcgattctt ttaaaacttt aggttttata taataaaatg tattataagg tatacccata
     2521 ttctttataa tgtacttata atctttattc ataatttcat taacatcatt ttgaactttt
     2581 gtcatagttt tttgctgtgt tgctttactt gctacttgat ttttctcttt agtattttct
     2641 ttatgacatc caacaagtat aatacctaaa atagttacac aaactaatga cctttttaac
     2701 ttcataaatc aatcctcctt tcttaaattt tatagtattt atctatatct caattt
//
LOCUS       DACTZW010000172         2739 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.175, whole genome shotgun sequence.
ACCESSION   DACTZW010000172 DACTZW010000000
VERSION     DACTZW010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2739)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2739)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2739
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.175"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            158..1081
                     /locus_tag="JAM15_18870"
     CDS             158..1081
                     /locus_tag="JAM15_18870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2520 domain-containing protein"
                     /protein_id="HAT6800310.1"
                     /translation="MGSGKVGTSLANYFLSKGYCVSGFYGKNQLSLLESINLTKTKIY
                     SNLRDIIYENDILFITTSDDSIEIIDKKLSKFNLKHKYICHTSGSLKSSILFCSKKAG
                     ALIYSIHPIFAFSNKNTDIKKMKDICFSIEGDNEQDDLVIQNFIDGLGNQFFIRDKDT
                     SSTYHLANVLVSNLVLSLLDIGVSYFIKLGLSEEESLKAISPLVKKNIENILDNGFTK
                     ALTGPVSRGDITPIRKHLSVLNKKDEDIYKILSLNLLKIIALRNDNSLKGTKNITIEN
                     AIENLISKSEKYKEIYKLLGGKNDEKYHTDF"
     gene            1056..1883
                     /gene="panB"
                     /locus_tag="JAM15_18875"
     CDS             1056..1883
                     /gene="panB"
                     /locus_tag="JAM15_18875"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009170647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HAT6800311.1"
                     /translation="MKNTIQTFKNAKYEGKKLSMLTAYDYSIAKIMDECDINGILIGD
                     SLGMVIKGEENTLSVTIDEIIYHTKAVKNGAKNALIVSDMPFLSYHVSIEDAVKNAGR
                     LIKEGGAHAVKLEGGSNVIKQIESIVNAQIPVMGHLGLTPQSVNSFGGFKVQGNTSET
                     ARQLIEDAKLIEKAGAFSIVLEGVPTKIADMVTNSISIPTIGIGAGINCDGQILVYQD
                     MLGMFGDFVPKFVKQYANIGDIMKDSIKNYILEVNTGAFPQEKHSFSINESELEKLY"
     gene            1902..>2739
                     /locus_tag="JAM15_18880"
     CDS             1902..>2739
                     /locus_tag="JAM15_18880"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015393293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HAT6800312.1"
                     /translation="MLVKEIKLLRNIIKDWRKHGYSIGLVTTMGFLHEGHQSLIKKAV
                     KENDKVVVSVFVNPTQFGPNEDFNSYPRDIDKDFKYCMDSGATVVFNPSPEEMYLKGN
                     CTTINVSGLTDFLCGAKRPVHFGGVCLVISKFLNIVTPDKAYFGEKDAQQLAVIKRMV
                     KDLNINTEIIGCPIIRENDGLAKSSRNTYLSEEERKSALILNKSLSLAKEELVKGNLN
                     PKNIKELITAKINSEHLAKIDYVEIVDSETLQPVKQIEHSILVAIAVFIGKTRLIDNF
                     TFE"
BASE COUNT         1089 a          335 c          454 g          861 t
ORIGIN      
        1 aaaatggtaa gatatttatg gatggtatct tgttataaga actatacttt aaatgttttt
       61 aattattttg tcttatgtaa ctcatatcct caggaatgag attagaaatt aagatgttgt
      121 atcacaaagt ggaggtgata ctattaaaat aggctttatt ggttctggaa aagttggaac
      181 atctttggca aattattttt tatcaaaagg ttattgtgtt tcaggctttt atggaaagaa
      241 tcaattatct ttattagaat caataaattt aacaaaaaca aagatttaca gcaatttgag
      301 agatataatt tatgaaaacg atatattatt tattacaaca tcagatgatt ctattgaaat
      361 tatagacaaa aaactttcca aatttaattt aaaacataaa tacatttgcc acacaagtgg
      421 ctctttaaaa tctagtatat tgttctgttc aaaaaaagca ggtgcattaa tttattctat
      481 ccatcctata tttgcatttt ccaataaaaa taccgacata aaaaaaatga aagacatttg
      541 tttttccata gaaggtgata atgaacaaga tgatttagtt attcaaaatt tcatagatgg
      601 tttgggaaac caatttttta taagagataa ggatacttca tccacttatc atctagctaa
      661 tgttttagtt tcaaatttag tattatcttt actagatata ggagtaagtt actttattaa
      721 attaggttta tctgaagagg aatctttaaa agctatcagt cctttagtaa aaaaaaatat
      781 agaaaatata cttgataatg gctttactaa agctcttact ggtcctgttt ctcgtggaga
      841 tataacacca ataaggaaac atctatctgt attgaataaa aaagatgagg atatctacaa
      901 aatactatcc ttaaacctac taaaaataat tgccttaaga aatgacaatt cattaaaagg
      961 tacaaaaaat attactatag aaaatgcaat cgaaaattta ataagtaaat ctgaaaaata
     1021 caaagaaatt tacaaacttt taggaggaaa aaacgatgaa aaataccata cagactttta
     1081 agaacgctaa atatgaagga aaaaaactat ctatgcttac tgcttatgac tactcaattg
     1141 caaaaataat ggatgaatgt gatataaatg gtattttaat aggagattca ttaggaatgg
     1201 tcataaaagg tgaagaaaac actctatctg ttactataga cgaaattata tatcatacaa
     1261 aagctgtaaa aaatggtgca aaaaatgcct taatcgtaag tgatatgcct tttctatctt
     1321 accatgtttc tatagaagat gcagttaaaa acgctggtag acttataaaa gaaggaggag
     1381 ctcatgctgt aaagttagaa ggtggctcaa acgttataaa gcaaatagaa agcattgtaa
     1441 atgctcagat acctgtaatg gggcatttag gattaactcc tcaatcagta aattcatttg
     1501 gtgggtttaa ggttcaagga aataccagtg aaacagcaag acaacttatt gaagatgcta
     1561 aattaataga aaaagcaggt gcattctcta ttgtccttga aggagtgcct acgaaaatag
     1621 ctgatatggt aactaattct atttcaattc ctacaatagg tataggggca ggaattaact
     1681 gcgatggaca aattttagtt tatcaagata tgttgggaat gtttggagat tttgttccta
     1741 agtttgtaaa gcagtatgca aatataggag atataatgaa agattcaatt aaaaattaca
     1801 tcctagaagt taatacaggt gcatttccac aagaaaaaca cagcttttca ataaatgaat
     1861 ctgagttaga aaaattatac taatattaag gatggtacaa aatgcttgta aaagaaatta
     1921 aattactaag aaatataatc aaagattgga gaaaacatgg ctattctata gggcttgtta
     1981 caacaatggg atttttacat gaaggacacc aaagtcttat aaaaaaagct gtaaaagaaa
     2041 atgataaagt agtagtgagt gtatttgtaa atccaactca atttggacca aatgaagatt
     2101 ttaatagcta tccaagagat atagataaag attttaaata ttgtatggat agtggagcaa
     2161 cagtagtctt taacccatca ccagaagaaa tgtatttaaa aggtaattgt actaccatta
     2221 atgtttctgg acttacagat tttctttgtg gagctaaaag acctgttcat tttggaggtg
     2281 tctgcctagt tatttcaaag tttctaaata tagtaacacc tgataaagct tattttggag
     2341 agaaggatgc ccaacaattg gctgtaatta aaagaatggt caaggattta aacataaata
     2401 cagaaataat aggctgtcct ataattcgtg aaaatgatgg attagcaaaa agttcgagaa
     2461 atacatatct ctctgaggaa gaacgaaaat ctgctctaat attaaataag agcttaagtt
     2521 tagcaaaaga agaattagta aaaggcaatc taaatccaaa gaatataaaa gaattaataa
     2581 cagctaaaat aaattctgaa cacttagcaa aaatagacta tgttgaaatt gtagatagtg
     2641 agacattaca acctgttaag caaatagaac attctatcct tgtggcaatt gctgtgttta
     2701 taggaaaaac cagactaatt gataatttta catttgagt
//
LOCUS       DACTZW010000173         2611 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.176, whole genome shotgun sequence.
ACCESSION   DACTZW010000173 DACTZW010000000
VERSION     DACTZW010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2611
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.176"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(215..1465)
                     /locus_tag="JAM15_18885"
     CDS             complement(215..1465)
                     /locus_tag="JAM15_18885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1015 domain-containing protein"
                     /protein_id="HAT6800313.1"
                     /translation="MATIKPFKAIRPNKYIVDKVAALPYDVMNSKEARRIAEGNPYSF
                     LHIDKSEIDLDENIDLYDEKVYLKARENLYEFRKQEILVKDDKECIYIYKQIMDGRAQ
                     VGIVACISVDESLNGTIKKHEYTRPEKEIDRTKHIKYCDANTGTILVTYKHQRVIDDI
                     INDFMDNNEPLYDFITDDKIEHTVWKIDSDDIIDNLVDKFEKLDYLYIADGHHRTASA
                     ENVAKEMRAKNPNYTGKEEFNYFIAMIAPDENLMVLDYNRVIKDLNGLSEEEFINKIK
                     ENFELEEIEGKEKYKPDKKGTFGMYLGDKWYKMKANKNLLEIEDPVDSLDISILQDYV
                     IDAILGIDNPRVDKRIDFIGGIRGLEELEKRVNEDMKVAFAMYPTSIEDLIRVADANK
                     IMPAKSTWFEPKVRCGLFLHEINE"
     gene            complement(1497..2438)
                     /locus_tag="JAM15_18890"
     CDS             complement(1497..2438)
                     /locus_tag="JAM15_18890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HAT6800314.1"
                     /translation="MYNILVTDGIEKEAARKLRELDFNVIEQFYEKDVLGDKLKDVDV
                     LVVRSATKVTKDVIDKALEGKKLKLIVRGGVGLDNIDVKYAQANGIKVMNTPNASSIS
                     VAELTIGQLFVLARFINTANVTMRDGKWEKKKYKGTEINGKTLGLIGFGRIAKEVAKR
                     AELLGMNVIYTDIMGEAQGFNNYKFCDMEEVLENADFLSLHIPFDKNKGAVITEKEIN
                     KMKKGAYLINCARGGLVDEKDLLKALDEGKLSAAAIDVYEQEPTLNLDLVNHPRVSPT
                     PHIGASTVEAQERIGDEIVNVIQDFFLDFNNLIGVAL"
BASE COUNT          786 a          497 c          245 g         1083 t
ORIGIN      
        1 taaaacctta taaatataca aatacaatta tatgaatttt catcctcaat tatagcatag
       61 aatatgacta tctatatcct aaaattatcc atttctaaaa aaaggtaact attattaaga
      121 atatcaactt atagaattta tattccacat acgattttca atcaaaaaaa caagggctaa
      181 aaagtgaatt gtacactttt tagcccttta ttaattattc atttatttca tgtaagaata
      241 gcccacatct tactttaggt tcaaaccatg ttgacttagc tggcattatc ttatttgcat
      301 ctgctactct tattaaatct tcaatactag taggatacat tgcaaatgct actttcatat
      361 cttcattaac tcttttttct aattcttcaa gacctctaat tccaccgata aaatcaattc
      421 ttttatctac tctaggattg tcaattccta aaatagcatc aataacatag tcttgtaata
      481 tagaaatgtc taatgagtca acagggtctt ctatttctaa taaattttta tttgctttca
      541 ttttatacca cttatcacct aggtacattc cgaaagttcc ttttttgtca ggtttatatt
      601 tttcttttcc ttctatttct tctagttcaa aattttcttt tattttattt ataaattctt
      661 cctcgcttaa accatttaag tctttgataa ccctattata atccaaaacc attaaattct
      721 catctggtgc aatcattgct atgaagtaat taaattcttc tttgccagta taatttggat
      781 ttttagctct catttctttg gctacatttt ctgctgaagc tgtcctatga tgaccatctg
      841 caatgtatag ataatctaat ttttcaaatt tatctactag gttatctatt atatcatcac
      901 tatcaatctt ccatactgta tgctctatct tgtcatctgt tatgaaatca tataaaggtt
      961 cattattatc cataaaatca ttgattatat catctatcac cctttgatgt ttgtaagtta
     1021 caagtatagt tcccgtatta gcatcacagt attttatgtg tttagttcta tcaatttcct
     1081 tttctggtcg agtgtactca tgttttttta ttgttccatt caagctttca tcaactgata
     1141 tacatgctac tataccaact tgagctctac catccatgat ttgtttatat atatatatac
     1201 actctttgtc atcttttact agaatttctt gttttcgaaa ctcatataaa ttttctcgcg
     1261 cttttaaata aactttttca tcatataaat ctatattttc atctaaatca atttctgatt
     1321 tatctatatg caaaaatgaa tatggattcc cttctgcaat tcttctagct tctttactat
     1381 tcataacatc gtaaggaagt gctgctactt tatctactat atatttattt ggtctaatcg
     1441 ccttaaatgg tttaatcgtt gccattacta atttcctcct aattatacaa aatattttat
     1501 aatgctaccc ctattagatt gttgaagtca agaaagaaat cttgaatcac atttactatt
     1561 tcgtctccta ttctttcttg agcttctact gtagatgccc caatatgagg tgtaggagaa
     1621 actcttggat gatttactaa gtctaaattt aatgtaggtt cttgttcata aacatctata
     1681 gcagctgctg ataatttacc ttcatctaat gcttttagta aatctttttc atcaactaaa
     1741 ccgcctcttg cacagtttat taaataagcc cctttcttca tcttatttat ttctttttca
     1801 gttattactg cccccttatt cttatcaaat ggtatgtgta aagataagaa atctgcattt
     1861 tctaaaactt cttccatatc acagaattta taattgttaa agccttgcgc ctcacccatt
     1921 atgtcagtat atataacatt catacctaat aattctgctc tctttgcaac ttcttttgca
     1981 attcttccaa aacctataag tccaagtgtc tttccattaa tttctgtacc tttatacttt
     2041 ttcttctccc attttccatc tctcatagtt acatttgcag tatttatgaa tcttgcaaga
     2101 acaaataatt gacctattgt aagctctgca acagatatac tgcttgcatt tggagtattc
     2161 ataactttta tgccattagc ttgagcatat ttaacatcta tattatccag acctactcca
     2221 cctcttacta tcaacttcaa ctttttaccc tctaatgctt tatctattac atctttagta
     2281 actttagtag ctgaacgtac tacaagtaca tcaacatctt taagtttatc tcctaaaaca
     2341 tctttttcat aaaactgctc tatcacatta aaatctaact ctctcaattt tctcgctgct
     2401 tctttctcta ttccatcagt aactaatata ttatacataa caaactcctc caatttttat
     2461 tcacttaatt tttccaattt ttatttttta aagtattttc atcaataaaa aactttactt
     2521 aatttaactt tctgtttata taattttcaa aatatttttt tattaaagtc atatcaaatt
     2581 ttcctattgt ttgttaaaaa tttaatatgt a
//
LOCUS       DACTZW010000174         2530 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.177, whole genome shotgun sequence.
ACCESSION   DACTZW010000174 DACTZW010000000
VERSION     DACTZW010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2530
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.177"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(<1..602)
                     /locus_tag="JAM15_18895"
     CDS             complement(<1..602)
                     /locus_tag="JAM15_18895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAT6800315.1"
                     /translation="MALGGGTFVTQNKILPGSYINFISAKRATSSLSDRGIVTIPLEL
                     DWGIDEDVFQVTSDDFEKYSVKYFGYDYTHEKLKGLRDLFKNIRLGYFYKLNKGVKAS
                     CTIATAKYSGIRGNDLKVTVTTNIDDNAKFDVVTLLDNKKVDTQIAKVITDLQDNDYI
                     TWKKDATLEASAGLVFTGGTNGEAVTGAEYQAFLDKIESYS"
     gene            complement(773..1210)
                     /locus_tag="JAM15_18900"
     CDS             complement(773..1210)
                     /locus_tag="JAM15_18900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800316.1"
                     /translation="MLNNIIDGISVKLDKSFGESYTIYSEDVEQGINEPCFFIVPINP
                     SKVSYPSGRTLKKNSFDVHYFPKSNDKSFEINEIAEMLLEELEYIEIDGDLVRGTNMN
                     FEIIDNVLHFFVDYNYFTIKSNDTDKMDTVELFGGLKRGDNFE"
     gene            complement(1203..1634)
                     /locus_tag="JAM15_18905"
     CDS             complement(1203..1634)
                     /locus_tag="JAM15_18905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HAT6800317.1"
                     /translation="MARGGSVDFKELKKLQRKLQRLENSQLDRFLKDCARELAARLVR
                     KARKPGRTPKKTGTLKDGWGGIAYARKLPVTKVGDNYVIEVINPTPYASYVEFGHRTR
                     NHKGFVKGKYMMTISVMELRGEADAIIEKKLLILLKGVFDA"
     gene            complement(1634..1996)
                     /locus_tag="JAM15_18910"
     CDS             complement(1634..1996)
                     /locus_tag="JAM15_18910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800318.1"
                     /translation="MVSKTRKAIEMLYRDKCTIVEYQPIKDPVTKRTNNKEVIVLENQ
                     PCKLSYKNIVSATEGKVAKLEQTIKLFISPDIEIKAGSKLIITNQNNITKEYVRSGES
                     AIYPNHQEIILELLEDKA"
     gene            complement(1990..2391)
                     /locus_tag="JAM15_18915"
     CDS             complement(1990..2391)
                     /locus_tag="JAM15_18915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800319.1"
                     /translation="MENNMIDDIERRLQGFGYVLKDGDKWLIDFVREKIENIIKLDCN
                     ISEIPKELHNIEVDMIVGEFLFTKKNIGQLDIESLNFEAVEKSISEGDTKVDFAIGSG
                     SQTPEQRFDSLIAYLTTYGKNKILTFRCLRW"
BASE COUNT          740 a          505 c          263 g         1022 t
ORIGIN      
        1 gaataacttt ctattttatc caagaaagct tggtactctg ctcctgtcac agcttcgcca
       61 ttagttccac cagtaaatac aagtcctgca cttgcttcta gtgttgcatc cttcttccaa
      121 gtgatatagt cattgtcttg taagtctgta ataacctttg ctatttgagt atctaccttc
      181 ttattatcta aaagtgttac aacatcaaac ttagcattat catctatatt tgttgtaact
      241 gttactttta aatcatttcc tctgatacca ctatattttg ctgtggctat agtacaactg
      301 gctttaacgc ctttatttaa tttataaaaa tatcccaacc ttatattttt gaataaatct
      361 ctcaagcctt tcagcttctc atgagtataa tcatatccaa aatacttcac tgaatacttc
      421 tcaaaatcat cactggttac ttgaaatacg tcttcatcta tgccccaatc taactctaaa
      481 gggattgtaa caatacctct atccgataat gaactggttg ccctcttagc tgaaataaaa
      541 tttatatagc tacctggtaa tattttattc tgtgttacaa atgttcctcc acctaacgcc
      601 aaattaactc actcctttca taaagctatt tattatttcc tctacctctg agaaggaata
      661 taaatcattt tcttttaaaa ttgcctttaa taaatctttt ctatttacat acttcttaga
      721 gttaactatc tgctccttag taaacttgta gttatcttct ttgcttaatg ttttactcaa
      781 aattatcacc tctcttcaaa ccaccgaata actctactgt atccatctta tctgtgtcat
      841 tactttttat agtaaagtag ttataatcaa caaagaaatg aagaacatta tctataattt
      901 caaagttcat atttgtacct ctgactaagt ctccatcaat ttctatatac tctaattcct
      961 ccagtaacat ctcagctatc tcatttattt caaatgattt atcattactt ttaggaaaat
     1021 aatgtacatc aaaagagttc ttttttaatg tcctgccact tggatatgat actttgcttg
     1081 gatttatagg aacaataaaa aaacaaggtt catttatacc ttgctccaca tcttcactat
     1141 aaattgtata actctctcca aacgatttat ctaattttac tgatattcca tcaattatat
     1201 tattaagcat caaatactcc tttaagtaat attaataact ttttctctat tattgcatct
     1261 gcttctcctc ttaattccat tactgaaata gtcatcatat atttcccttt aacaaagcct
     1321 ttgtgatttc tagttctgtg cccaaactct acatatgagg catagggagt tgggttaata
     1381 acttctataa cataattatc tccaacttta gtaacaggaa gcttcctagc ataagctatc
     1441 ccaccccaac catcttttag agttccagtc ttttttggtg tacgtccagg cttcctagct
     1501 ttacgaacaa gtcttgcagc taattctctt gcacaatctt ttaaaaatct atcaagctga
     1561 ctgttttcta atctttgtaa tttcctttgc aacttcttta gttctttaaa atcaacgctt
     1621 ccacccctag ccattatgct ttatcctcca gtaattctaa tattatctct tgatgattag
     1681 gatatatagc tgattctcca cttcttacat attcttttgt aatattattt tgattagtta
     1741 taataagttt tgaacctgct ttaatttcta tatctggaga tataaagagt ttaatagttt
     1801 gctctagctt agctactttc ccttctgtag cagaaactat atttttatat gaaagtttac
     1861 atggttgatt ttctaataca atcacttctt tattgttagt tcgttttgtt acagggtctt
     1921 tgattggctg atactcaact atagtacatt tatctctata taacatttct attgcttttc
     1981 tagttttact taccatctta agcacctaaa ggttaatatc ttattcttac cataagtagt
     2041 aagataagct attaagctat caaagcgttg ttctggtgtt tgagagccac ttcctatggc
     2101 aaaatctacc tttgtatcac cttctgatat agacttttct acagcttcaa aattaagact
     2161 ttctatatct aattgcccta tatttttctt agtaaataag aactctccaa ctatcatatc
     2221 tacttctata ttgtgtaact cttttggaat ttcacttata ttacaatcta gtttaataat
     2281 attttctatt ttttctctta caaaatctat taaccattta tctccatcct ttagaacata
     2341 tccaaatcct tgaagtcttc tttctatatc atcaatcata ttattttcca caattttcac
     2401 ctacttttta gtaagtttat ttttctcttt aagctgttta ttttcttctt ctaaagattc
     2461 aacttttgac cttaaaatat tattttcagc tattaaatct tttacattta atgacttgcc
     2521 atactttact
//
LOCUS       DACTZW010000175         2509 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.178, whole genome shotgun sequence.
ACCESSION   DACTZW010000175 DACTZW010000000
VERSION     DACTZW010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2509
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.178"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(<1..602)
                     /locus_tag="JAM15_18920"
     CDS             complement(<1..602)
                     /locus_tag="JAM15_18920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAT6800320.1"
                     /translation="MALGGGTFVTQNKILPGSYINFISAKRATSSLSDRGIVAMGLEL
                     DWGIDEEVFQVTSDDFEKYSVKYFGYDYTHEKLKGLRDLFKNIRLGYFYKLNKGVKAS
                     CTIATAKYSGIRGNDLKVTVTTNIDDNAKFDVVTLLDNKKVDTQIAKVITDLQDNDYV
                     IWKKDATLEASAGLVFTGGTNGEAVTGAEYQAFLDKIESY"
     gene            complement(773..1210)
                     /locus_tag="JAM15_18925"
     CDS             complement(773..1210)
                     /locus_tag="JAM15_18925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800321.1"
                     /translation="MLNNIIDGISIKLDKTFGESYTIYSEDVEQGINEPCFFIVPLNP
                     SKVSYPSGRTLKKNSFDVHYFPKSNDKSFEINEVAEMLLEELEYIEIDGDLVRGTNMN
                     FEIVDNVLHFFVDYNYFTIKNNDVNKMDTVELFGGLKRGDNFE"
     gene            complement(1203..1628)
                     /locus_tag="JAM15_18930"
     CDS             complement(1203..1628)
                     /locus_tag="JAM15_18930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HAT6800322.1"
                     /translation="MARWGSVDFREFKRACKKMEKFTKIDLDKFCKDAARELAARLLG
                     KVIRRTPVDTGFLKQGWNGVAYARSLPVYKQGNNYIIEVVNPTEYASYVNFGHRTKDG
                     KGWVKGQHFLTISEMELQSQIDKIIEKKLLILLKGVFDA"
     gene            complement(1628..1975)
                     /locus_tag="JAM15_18935"
     CDS             complement(1628..1975)
                     /locus_tag="JAM15_18935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800323.1"
                     /translation="MVSKTRKAIEMLYRDKCTIVEYQPVKDPVTKRTNNKEVIVLENQ
                     PCKLSYKNIVSATEGKVAKLEQIIKLFISPNINIKAGSKLIINNKEYARSGEPAIYPN
                     HQELLLELLEDKA"
     gene            complement(1969..2370)
                     /locus_tag="JAM15_18940"
     CDS             complement(1969..2370)
                     /locus_tag="JAM15_18940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800324.1"
                     /translation="MENNIIDEIEKRLESFGYILKDGDKWLIGFVREKIENIIKLDCN
                     IKTMPIELKEIEVDMIVGEFLFTKKNMGQLDIESINFEAVEKSISEGDTKVDFAIGSG
                     SQTPEQRFDSLIAYLTTYGKNKILTFRCLRW"
BASE COUNT          742 a          510 c          245 g         1012 t
ORIGIN      
        1 ctatagcttt ctattttatc caagaaagct tggtactctg ctcctgtcac agcttcgcca
       61 ttagttccac cagtaaatac aagtcctgca cttgcttcta gtgttgcatc cttcttccaa
      121 attacatagt cattgtcctg caagtctgta ataacctttg ctatttgagt atctaccttc
      181 ttattatcta aaagtgttac aacatcaaac ttagcattat catctatatt tgttgtaact
      241 gttactttta agtcatttcc tctgatacca ctatattttg ctgtggctat agtacaactg
      301 gctttaacgc ctttatttaa tttataaaaa tatcccaacc ttatattttt gaataaatct
      361 ctcaagcctt tcagcttctc atgagtataa tcatatccaa aatacttcac tgaatacttc
      421 tcaaaatcat cactggttac ttggaatact tcttcatcta tgccccaatc taactctaaa
      481 cccattgcaa caatacctct atctgataat gaactggttg ccctcttagc tgagataaaa
      541 tttatatagc tacctggtaa tattttattc tgtgttacaa atgttcctcc acctaacgcc
      601 aaattaactc actcctttca taaagctatt tattatttcc tctacctctg agaaggaata
      661 taactcattt tcttttaaaa ttgcatttaa taagtctttt ctatttatat acttcttaga
      721 attaactatc tgctccttag taaacttgta atcggttcct ttgcttaatg tcttactcaa
      781 aattatcacc tctcttcaaa ccaccgaata actctactgt atccatctta ttgacatcat
      841 tattttttat agtaaaatag ttataatcaa caaagaaatg aagtacatta tctacaattt
      901 caaagttcat atttgtacct ctgactaaat ctccatcaat ttctatatac tctaattcct
      961 ccagtagcat ctcagctacc tcatttattt caaatgattt atcattactt ttgggaaaat
     1021 aatgtacatc aaaagagttc ttttttaatg tcctgccact tggatatgat actttgcttg
     1081 gatttaaagg aacaataaaa aaacaaggtt catttatacc ttgctccaca tcttcactat
     1141 aaattgtata actctctcca aatgttttat ctaatttaat agatattcca tcaattatat
     1201 tattaagcat caaatactcc tttaagtaat attaataact ttttctctat aatcttatca
     1261 atttggcttt gtagttccat ctctgaaatt gttaagaaat gttgtccttt aacccatccc
     1321 ttaccatctt tagttctatg cccgaaattt acataacttg catattcagt cggattaaca
     1381 acctctataa tataattatt tccttgttta tacacaggaa gcgacctagc ataagccact
     1441 ccattccatc cttgttttaa gaatcctgta tcaactggtg ttcttctaat tactttccca
     1501 agtaatcgtg ctgctaattc tcttgctgca tccttacaaa acttatctaa atcaatcttt
     1561 gtaaatttct ccattttctt acaagctctt ttaaactctc taaaatcaac actaccccat
     1621 ctagccatta tgctttatcc tctagtaatt ctaataatag ttcttgatga tttggatata
     1681 tagcaggttc tccacttctt gcatattctt tattatttat aataagtttt gaacctgcct
     1741 taatatttat atttggagat ataaagagtt taattatttg ctctagcttc gctactttcc
     1801 cttctgtagc agaaactata tttttatatg aaagtttaca tggttgattt tctaatacaa
     1861 tcacttcttt attgttagtt cgttttgtta cagggtcttt gactggctga tactcaacta
     1921 tagtacattt atctctatat aacatttcta ttgcttttct agttttactt accatcttaa
     1981 gcacctaaag gttaatatct tattcttacc ataagtagta agataagcta ttaagctatc
     2041 aaagcgttgt tctggtgttt gagaaccact tcctatagca aaatctacct ttgtatcacc
     2101 ttctgatata gacttttcta cagcttcaaa gttaatgctt tctatatcta attgacccat
     2161 atttttcttg gtaaataaga actctccaac tatcatatca acttcaattt ctttcaattc
     2221 aattggcata gtttttatat tacaatctag tttaataata ttttctattt tttctcttac
     2281 aaaacctatt aaccacttat ctccatcttt taatatatat ccaaaacttt caagtctttt
     2341 ttctatttca tcaattatat tattttccat aattttcacc tactttttag taagtttatt
     2401 tttctcttta agctgcttat tttcttcttc taaagactca acttttgacc ttaaaatatt
     2461 attttcagct attaaatctt ttacacttaa tgacttgcca tactttact
//
LOCUS       DACTZW010000176         2509 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.179, whole genome shotgun sequence.
ACCESSION   DACTZW010000176 DACTZW010000000
VERSION     DACTZW010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2509
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.179"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(<1..488)
                     /locus_tag="JAM15_18945"
     CDS             complement(<1..488)
                     /locus_tag="JAM15_18945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800325.1"
                     /translation="MDNNINKKELFKKVEGRLHHYKFLSAEIKNLELDIESRENEIFG
                     CKAVGYDEKVSPTYAFNSSVENEIIKKERDITRLKKLKKDKEIEKKKIENALTCLDIR
                     EEHFFKLFYNSRMKNSMVYISLEMNSDRKTCRCVRERLVYKVMDMLYPRIKENELPLF
                     KN"
     gene            complement(582..1190)
                     /locus_tag="JAM15_18950"
     CDS             complement(582..1190)
                     /locus_tag="JAM15_18950"
                     /inference="COORDINATES: protein motif:HMM:NF013826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800326.1"
                     /translation="MPSKYYAVRKGHKTGIYDNWDEAYKQVRVYSCAEYKGFYSLKQA
                     KLYLEGDNLGLEDIKQDKDTMIAYISGSYSEKLNKYGCGVVICRPNGMVYEEWENGGN
                     KAALLLKDIAGEIKAAIIAMRIKEMEVKKLIIVYNFEGISSLINKSRKAENEIEEIYV
                     NYYEENIKDYVDVSFKHIDNCSNDAMYGRAKYLAIHNAYRYC"
     gene            complement(1206..1649)
                     /locus_tag="JAM15_18955"
     CDS             complement(1206..1649)
                     /locus_tag="JAM15_18955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HAT6800327.1"
                     /translation="MKINFTIDGEPKAKARPRMSTANGKAYTPDQTVLYENWIRLMYN
                     STVKHFFEGNVKMTVICYFDITKKDREALKKNKVNTKAYKDAIGKIEGLIRPSKKPDL
                     DNIIKSVADSLNGIAYKDDSQIVEVVSKKYYSDKPRVEVVLEDVT"
     gene            complement(1639..2043)
                     /locus_tag="JAM15_18960"
     CDS             complement(1639..2043)
                     /locus_tag="JAM15_18960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800328.1"
                     /translation="MKNKKDVWLYSWDDEYFASDEYESKEEAIQGAKEELRRFGEVSR
                     LVYVGQKEEVNIPNLNVEDALERVQDRIDNEFMGYGEDWFENIRVEDILILENRISEV
                     FKKWIDEFGYKPYWFVVRDTEEIELNEVANED"
     gene            complement(2186..>2509)
                     /locus_tag="JAM15_18965"
     CDS             complement(2186..>2509)
                     /locus_tag="JAM15_18965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor-like protein"
                     /protein_id="HAT6800329.1"
                     /translation="ENYNCENYFEDMCMLERIEINNLKVCESYIEGKNELYKLENGYT
                     IHPKDLKMVKSKDYSVEVTHIPTGITVKCRSTNSILKNKNKCLEALEEELIKINSHLE
                     LEDLF"
BASE COUNT          709 a          511 c          213 g         1076 t
ORIGIN      
        1 taatttttaa ataatggtag ctcattttcc ttaattcttg gataaagcat atccataact
       61 ttatatacta acctttccct tacacatcta catgttttcc tatctgagtt catttctaaa
      121 gatatataaa ccatactatt tttcattctg ctattataaa acagtttaaa aaaatgttct
      181 tctcttatat ctaagcatgt aagtgcattt tctattttct tcttttcaat ttccttatct
      241 tttttcagtt ttttcaatct agtaatatct ctttcttttt ttataatctc attctccaca
      301 cttgaattaa aagcatatgt tggacttact ttttcatcat atccaacagc cttacaccca
      361 aatatctcat tttctctact ttctatatct aattcaagat ttttaatttc tgcacttaaa
      421 aatttataat gatgtagtct accttctact tttttaaata gttctttttt attgatatta
      481 ttatccatac ttccacactc ctgtttatgt tataataatc ttggataaaa gttttatatt
      541 tttgacgact ggagtgtgaa agcactcctt ttctcttttt gttaacaata tctataagcg
      601 ttatgtatag ctaagtattt agctcgacca tacatagcat cattagagca attatctata
      661 tgtttaaaac ttacatctac ataatcttta atattttctt cataatagtt aacatatatt
      721 tcttctattt cattttcagc ttttctactt ttgtttatta agctagatat accttcaaag
      781 ttgtaaacta ttatcaactt ctttacttcc atttctttta ttctcatagc tattattgct
      841 gcttttattt cacctgctat atcttttaac aataatgctg ctttatttcc tccattctcc
      901 cattcttcat aaaccattcc attaggtcta catataacaa ctccacaacc atatttattc
      961 aatttttctg aataacttcc acttatgtat gctatcatgg tgtctttgtc ttgttttata
     1021 tcctctaacc ctaaattatc accttctaga tatagttttg cttgttttaa tgagtaaaat
     1081 cctttatatt ctgcacatga ataaactctc acttgtttgt atgcttcatc ccaattatcg
     1141 tatattccag ttttatgacc ttttctaaca gcataatatt tactaggcat tttatttaat
     1201 cctccttaag taacatcttc caatacaact tcaactcttg gcttatcact ataatatttc
     1261 ttactcacca cttctacaat ttgagaatca tctttgtatg ctataccatt caagctatca
     1321 gctacagact tgattatatt atctaaatca ggctttttac ttggtcttat taacccttct
     1381 atcttgccta tagcatcctt atacgcttta gtatttacct tatttttctt tagtgcttct
     1441 ctatcttttt tagtaatgtc aaagtaacaa ataactgtca ttttcacatt accctcaaag
     1501 aaatgcttta ctgtagaatt gtacataagt ctaatccaat tttcatagag tacagtttgg
     1561 tcaggtgtat aagccttacc atttgctgta ctcattctag gtcgcgcttt tgcttttggt
     1621 tctccatcta ttgtaaaatt aatcttcatt tgcgacctca tttagttcta tttcttccgt
     1681 atctctaaca acaaaccaat atggtttata tccaaattca tctatccatt ttttaaatac
     1741 ttcgcttatt ctattctcta gtattaatat atcttcaaca cgtatatttt caaaccaatc
     1801 ttctccatac cccataaatt cattgtcaat tctatcttga acacgttcta aagcatcctc
     1861 tacatttaga ttaggtatat taacttcttc tttttgccca acgtaaacca atcgactgac
     1921 ctccccaaac cttctaagtt cttccttagc tccttgaata gcttcctctt tactttcgta
     1981 ttcatcactt gcaaaatatt catcatccca actatatagc cacacatctt ttttattttt
     2041 catataaatt cctcctctat ttatttttct tcttagcttt ctttctacag tccttacaac
     2101 aataaatatc cttagatttt tccttaagat aaaataattt tccacaccaa ctgcatattc
     2161 ttcgtttcat aagctcactt cctatttaga ataaatcttc tagctctaag tgtgagttta
     2221 tttttattag ttcttcttct agagcttcca aacacttgtt tttatttttt aaaatactat
     2281 ttgtagaacg acattttact gtaataccag ttggaatatg agtaacttca acagaataat
     2341 ctttactttt caccattttc aaatctttag gatgtatagt atatccgttt tctaatttat
     2401 atagctcatt tttaccttca atgtaacttt cacacacttt caggttatta atttcaattc
     2461 tttcaagcat acacatatct tcaaagtaat tttcgcaatt ataattttc
//
LOCUS       DACTZW010000177         2487 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.180, whole genome shotgun sequence.
ACCESSION   DACTZW010000177 DACTZW010000000
VERSION     DACTZW010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2487
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.180"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(14..1594)
                     /locus_tag="JAM15_18970"
     CDS             complement(14..1594)
                     /locus_tag="JAM15_18970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional ADP-dependent NAD(P)H-hydrate
                     dehydratase/NAD(P)H-hydrate epimerase"
                     /protein_id="HAT6800330.1"
                     /translation="MLIGTSKLIRNVDTACVEEVGIPMIVLMENAVISAMKNMDIDMY
                     NSYTVVCGVGNNGGDGLGIARHLNTYGKEVNVFLVGNLEKLSECSKINYNVLLNMGIN
                     IININKNDLSEKNYGDENEVDKIIKVEKQNIIKNKNLTIFKDRVSKSDVVVDAIFGTG
                     LKRDITGIFKEVIDIVNDNSKNTYSIDIPSGIDSDNGNVLGTCIRANKTISFEFYKRG
                     FLNYDTSTLIGDVVVEKIGVPDFITRKYHDEEFITDKTFVKNNIRRRDKHGFKSDFGK
                     VSIVAGSKGFYGASFIATESAVKSGSGLVTLISSEDVQEKVSIRLTEAMTLNFEEERL
                     NKLLNSSDAIGFGPGMGDNSQTFDKLLKIVENSNCPIVLDADGLNVMKDRCYKFLEWK
                     NRFVITPHLGEMARLTGDSIGYIREHRVDVAKEFAQKYNLVVLLKGYQTVITDGKKTY
                     INPTGNSCMATGGMGDCLLGMITSFIGQGMDILEATVSGAYIHGYIGDKLSKAMYTVN
                     ATDLISNISLTMKELLDI"
     gene            2393..>2487
                     /locus_tag="JAM15_18975"
     CDS             2393..>2487
                     /locus_tag="JAM15_18975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008975996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6800331.1"
                     /translation="MSGIISVMTQSLILSIMALGVYITYKILDFP"
BASE COUNT          843 a          424 c          225 g          995 t
ORIGIN      
        1 attttttaat caattatata tccaacaact ctttcattgt taatgaaatg ttacttatta
       61 aatccgtagc atttaccgta tacattgctt tgctcaattt atctcctata tagccatgta
      121 tatatgctcc actaactgta gcttccaata tatccatacc ttgacctata aatgaagtaa
      181 tcattccaag caaacaatca cccattccac cagttgccat acagctattt cctgtaggat
      241 ttatatatgt ttttttacca tctgttatga cagtttgata accttttaaa agcaccacca
      301 gattatattt ttgagcaaat tcttttgcaa catctactct atgttctctt atatacccaa
      361 ttgaatctcc tgtcaacctg gccatttctc ccaaatgagg tgtaattaca aatctatttt
      421 tccattctaa aaacttataa catctgtcct tcataacgtt caatccatct gcatctaata
      481 ctattgggca attagaattt tctactatct taagtaattt atcaaatgtt tgactattat
      541 ctcccatacc tggaccaaaa ccaattgcat cactagaatt aagtaattta tttaatcttt
      601 cttcttcaaa atttaaagtc attgcttctg taagtctaat agataccttt tcttgcacat
      661 cttcactact aattaatgtt acaagtccac tcccactctt aacagcagat tcagttgcta
      721 tgaaacttgc accataaaat ccttttgaac ctgcaactat agatactttt ccaaaatcac
      781 ttttaaaacc atgcttatct cttcttctaa tattattttt tacaaaagtc ttatcagtta
      841 tgaactcttc atcatggtat tttcttgtaa taaaatctgg aacacctatc ttttctacaa
      901 ctacatcacc tataagtgtg ctagtgtcat agtttagaaa acctctttta taaaactcaa
      961 agctaatcgt tttgtttgct ctaatacaag ttcctaatac atttccatta tcgctatcta
     1021 tacctgaagg aatatctata gaatatgtat ttttgctatt atcgtttact atgtcaataa
     1081 cttctttaaa aataccagtt atatcacgtt ttaatccagt cccaaatata gcatctacta
     1141 caacatcact tttagatact ctatctttaa aaattgttaa atttttattt tttataatat
     1201 tttgtttctc aactttaata attttatcta cttcattttc atctccataa tttttttcac
     1261 ttaaatcatt tttattaata tttataatat taattcccat atttaaaagt acattgtaat
     1321 ttattttaga gcattcactt agtttttcaa gattacctac taaaaatacg tttacttctt
     1381 ttccatatgt atttagatgt cttgctattc caagaccatc tcctccatta tttccaacac
     1441 cacatacaac tgtataacta ttatacatgt ctatatccat atttttcatt gcagatataa
     1501 ccgcattttc catcaataca atcattggaa tccctacttc ttctacacat gcagtatcaa
     1561 catttctgat taatttagat gtacctatta gcataaatta tcactcctat aaagttaaag
     1621 acttcttaaa tacttaccaa aaatatctat tgaaatcttt ttaatcccat aaatatcata
     1681 aataaaatca ctaaaactaa gagttttgaa ataatttaaa ataacaaaaa attttgaatt
     1741 aaaacaatta tttaatttat tataccatat aatttaagtt attatgttga tttaaaacct
     1801 atttacacta attatctaaa tatctcttta tttttataat cttttatgac ttatttatat
     1861 ttttcatttt tataaaaaaa caataattaa gaatataact atattctaca tgtaaaaatt
     1921 tttttattta aactcaattt tctgataatt tgataatttt tcaaaattta tagttgactt
     1981 ttatttttta ctgtattaaa ctaattacta tacaaaacag aaaacaaaat tttcaaaatt
     2041 attaaattaa aaggagaggt aaatatgaag actttattaa acaaacaagt acgatttttt
     2101 agtagccaat ttagttaggg tttgtaccta agttaagaca aattgtcata acatagatac
     2161 aagcccctta ggattatgat ttttaaggat tgtatctatg ttggctatag taattgttgt
     2221 taaagttttt attttatcat cataatatag agccacatgg attatactgt gtggcttatt
     2281 cgaatttttg ccatacagtt atatatactg tgtggttttt ttatatcaaa atcatttttt
     2341 aaaaccaaat ttaaaaaacc atttaaaata ttttcaaagg ggtgttttat ttatgtcagg
     2401 tattatatct gtaatgacgc aaagtttaat tttatcgatt atggcactgg gagtttatat
     2461 aacttacaaa atcctagatt ttccaga
//
LOCUS       DACTZW010000178         2402 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.181, whole genome shotgun sequence.
ACCESSION   DACTZW010000178 DACTZW010000000
VERSION     DACTZW010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2402
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.181"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(400..771)
                     /locus_tag="JAM15_18980"
     CDS             complement(400..771)
                     /locus_tag="JAM15_18980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6800332.1"
                     /translation="MESLGDRIANLRKELDINQKELATKVGITEASLSRYENNLREPK
                     SEIIVRLAKALETSTDYLLGVNDNTKISKEDKLIIENLSVSEKTKKLLEKIYSLEKED
                     REAIEKMIDNAYLKRFLKEEN"
     gene            1320..1577
                     /locus_tag="JAM15_18985"
     CDS             1320..1577
                     /locus_tag="JAM15_18985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800333.1"
                     /translation="MIIIRSQDKTNLMQINQIKIDGSQVYAVFESKIDTVKIGDYENN
                     TRAIQVLDNIQNFIENGTKYDYITSNKVRYNVNKIFQMPAK"
     gene            complement(1687..2367)
                     /locus_tag="JAM15_18990"
     CDS             complement(1687..2367)
                     /locus_tag="JAM15_18990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAT6800334.1"
                     /translation="MIWTFYSFICVILPCLIYQIVVIKRKNLKVEKNVMIHLVWVYIF
                     LLYIYLALSKAGIGSIWDIGRYSGLFRIDEINLIPFDSVGILTYILNIIMFMPLGFLL
                     PLIWKNFRNIINVSLTGLGFSLAIELCQLFNLRATDIDDLMMNTLGAVLGYFIWVGVN
                     NLFNLIKKKDIFPSIYKNIIQDEIAITIDDDISKKITSLYKNEAIIYLILAVLGEFLL
                     FNWSIIPY"
BASE COUNT          971 a          267 c          279 g          885 t
ORIGIN      
        1 aaaatcatcc tgaaaaatat ataaaaatag aaaaaacata caagattcta caataataga
       61 tttttttgtt attattacga gttttttatt gcaactgtag aataaaagta ttattatata
      121 attaagataa ttatctaggg aaattttgga taatcaaaat atattttata aaatcaaaat
      181 acaattacat aaactttatt aaaaatttgt tgggaatttc tgactagcat taagaacgta
      241 agtttgttgg gggatggtat atgtggaaaa gtcaaacact actgttacaa aaaaagaaaa
      301 aattgaagat ataggaatga aattagaaca tttattgagt gaagatatta ctttttatga
      361 attattactt gagattttgt ataaagaaaa agaagagaat taattctctt ctttaaggaa
      421 tctttttaaa taggcattat caatcatttt ttctatagct tctctatctt ctttttcaag
      481 agaatatatt ttttctaaga gcttttttgt tttttcactt actgataagt tctctatgat
      541 taatttatct tctttgctta tttttgtatt atcatttacg cctaataaat aatctgttga
      601 tgtttctaat gcttttgcta atctaactat tatttcactt ttaggttctc ttaaattatt
      661 ttcataacgt gacaagctag cctcagttat accgacttta gtagcaagtt ctttttgatt
      721 tatatctaat tcttttcgta gatttgctat tctatctcct aaactttcca tatgtacatc
      781 actccttacc gaaattataa gttattttga taaaaagtaa aataaaatta ccaaaaatat
      841 aaaaaaaaag ggttaaaata ataaaatata ttgaaaatta ccatttgtat atgtataata
      901 tgaattatac aaatggtaat ttgatgagag gtggtatgtt gaaataagaa actgaattaa
      961 ttaataaata tatagaaagt tttgaaaacc cttaattgag atataaacaa tatgtacaaa
     1021 attttttgca agtaaaatta ccaaatgtat aaaataaatc agtagcatag ataattttat
     1081 gctttaatac attagattat ttaatttagt tataatggtc aaaaatgcaa tctacaaata
     1141 aaacaaagta ttatcaaaaa agtattcttt aagagaattt tttattagag atgtaattga
     1201 tataaataat cgtattaaaa aataaaatac taagtttaaa aatttaaata atctataaat
     1261 caattataaa atattatttc ttagaaatta aaatgaatta agtaaatgga ggaattgata
     1321 tgataataat tagaagtcaa gataaaacta atttaatgca gataaaccaa attaaaatag
     1381 atggtagtca agtttatgca gtatttgaaa gtaaaattga tactgtaaaa ataggagatt
     1441 atgaaaataa tacaagagct atacaagtgt tggacaatat acaaaacttc attgaaaatg
     1501 gaacaaaata tgattatata acatcaaata aagtcagata caatgttaat aaaatatttc
     1561 agatgccagc taaatagtga gtgtgcattt tagtttaata actaaagccc actttctttt
     1621 gtagtatgaa agagggcttt acatatttgt aaatatcgaa gtacacttgt tttatcaata
     1681 aattatttaa taaggtataa tggaccaatt aaacaataaa aattctccta aaacagcaag
     1741 tattaaatat ataatagctt catttttgta aagagaggta atttttttgc ttatgtcatc
     1801 atcaattgta atagcaattt catcttgaat aatattttta tatatagatg ggaaaatatc
     1861 ttttttcttt ataagattaa ataaattatt tacacctacc catataaaat atcctaaaac
     1921 agcacctaat gtgttcatca ttaaatcatc aatatctgta gctcttaagt taaacaattg
     1981 acaaagttca attgctaatg aaaaacctaa tccagttaat gaaacattga taatatttct
     2041 aaaatttttc caaattaaag gtagtaaaaa tcctaaaggc ataaacataa ttatatttaa
     2101 aatatatgtt aagatgccaa ctgagtcaaa aggtattaga tttatttcat caattctaaa
     2161 aagcccacta taccttccta tatcccatat gctaccaatt ccagctttac taagtgctag
     2221 atagatatat aataaaaaaa tatataccca tactaaatgt atcattacat tcttttcaac
     2281 tttcaaattt tttcgtttta taacgactat ttggtatatt aagcatggta atataacgca
     2341 aataaatgaa taaaatgtcc atatcatttt attttgtccc ctttcaaatt tatgttttta
     2401 gt
//
LOCUS       DACTZW010000179         2307 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.182, whole genome shotgun sequence.
ACCESSION   DACTZW010000179 DACTZW010000000
VERSION     DACTZW010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2307)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2307)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2307
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.182"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            496..1167
                     /locus_tag="JAM15_18995"
     CDS             496..1167
                     /locus_tag="JAM15_18995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAT6800335.1"
                     /translation="MSKTKVSSEQKIEAIESYLKGENSVIKIMEELNIGKRTFREWMR
                     NYETFGNDGLIKQSHKSCYSKEFKLNAIESYLNGEGSYDTISKKYKMRSVHPLKAWVK
                     EYNLHKVIKETPKGGLFMETRKTTLDERAEIVKDCIEHGLNYNLIAKKYFVSYSQVRR
                     WTLKYKENGIDALEDRRGKSKKEDELTQLDEIKLELKIVKAEKHKLQLENEFLKKLKI
                     IERGW"
     gene            1161..1421
                     /locus_tag="JAM15_19000"
     CDS             1161..1421
                     /locus_tag="JAM15_19000"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAT6800336.1"
                     /translation="MVITLSKNEDKYKAIQSLFNEKKASLIQLCEIAKVNRSGYYKWL
                     NRDKSNLELENIKLATLITKIYEEKKGVFGSLRMTLQLNREL"
     gene            1456..2061
                     /locus_tag="JAM15_19005"
     CDS             1456..2061
                     /locus_tag="JAM15_19005"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAT6800337.1"
                     /translation="MRAVGLRSICRKKKFSYVKCTQEVIAENVLNRKFSADKTSQKWL
                     TDVTEFKLTDGTKAYLSAILDLGDRSIVSYVIGKSNNNNLVFETFNKAIEVYPNAKPI
                     FHSDRGYQYTSRVFKSKLLTQGMIQSMSRVGRCIDNAPMEGFWGILKVEMYYLRKFDT
                     YEQLVNAIEDYIHYYNNFRYQKRLNSMSPLEFRKYLSTEIA"
BASE COUNT          928 a          256 c          359 g          764 t
ORIGIN      
        1 tagtatatgt aatctttagt catcttctta ccagtttttt atccactttt ctaatgaagt
       61 tattttttca tatgttaatt cctcttgaaa taatgatact aaaagacttt ttataaaatt
      121 ataacttaaa agtttatgta tttttttgat atgaatttat aatacttatc ttctttaatt
      181 gagattgtgt atatttaact aaatattaca acaataattc tatgaaatca aatcaattat
      241 ttacatattt ttttagaaca ataataagta tatattcaca aaattttgtg ttaatatttt
      301 taatttgtga tataataaaa gcaaggaaac atattttact taactttgag tgatgtttcc
      361 ttcaataaat tattttgaag atttactttt ctggaacttt atattaagtt cccagccact
      421 cttagttgtg aactataccc ctcttaggag acagttgaaa tatgtaaaac tgtctgaaac
      481 taggagggtt ttgttatgtc taaaactaaa gtatcatcag agcaaaaaat cgaagcaatt
      541 gaatcatatt taaagggtga aaattcagta ataaaaataa tggaagaatt aaatattgga
      601 aaacgtacat tcagagagtg gatgcgaaat tatgaaactt ttggaaatga tggtttaata
      661 aaacaaagtc acaaatcatg ctattctaaa gagtttaaat taaatgctat agaatcttat
      721 ctaaatgggg aaggatctta tgatactatc tcaaaaaaat ataaaatgag atcagttcat
      781 ccactaaaag cttgggttaa agagtataat cttcataagg tgataaaaga aaccccgaag
      841 ggaggactct ttatggagac tagaaaaaca acattagatg aaagagctga aattgttaaa
      901 gattgtattg aacatggtct taattacaat ttaatagcaa aaaaatactt tgtttcatac
      961 agccaagtta gaagatggac tcttaaatat aaagaaaatg ggatagatgc tttagaagac
     1021 cgaagaggta aatcaaaaaa agaagatgag ttaactcaat tagatgaaat aaagttggaa
     1081 ttgaaaattg taaaagcaga aaaacacaaa ttacaactgg agaatgaatt cttaaaaaag
     1141 ttaaaaatca tagaaagagg gtggtaatta cactatccaa gaatgaagat aaatataaag
     1201 cgattcaatc cttattcaat gaaaaaaaag cttcgcttat acaattatgt gaaatcgcta
     1261 aagtaaatcg ttctggatac tataaatggc tcaatcgaga taaaagtaat ttagaacttg
     1321 aaaacattaa attagcaact ttgataacta agatatatga agaaaagaag ggagtttttg
     1381 gctctttaag gatgaccttg cagttaaaca gagagttata aacttaatgt caatcacaag
     1441 agagtgtaca gactaatgag agccgtaggc ttaaggtcta tttgtagaaa aaagaaattt
     1501 agttatgtta aatgtacaca agaagtaatt gctgaaaatg tattaaatag aaaatttagt
     1561 gcagataaaa cttctcaaaa atggttaaca gatgtaactg aatttaaatt aaccgacggg
     1621 acaaaggctt atttaagtgc aattctggat ttaggtgata gaagcatagt ttcatatgtt
     1681 attggaaaat caaataacaa taacttagta ttcgaaactt ttaataaagc aatagaagta
     1741 tatccaaatg caaaacctat ctttcatagt gatagaggct atcagtatac tagcagggtg
     1801 tttaaatcaa aacttttaac acaaggcatg atacaaagta tgtcaagagt tggtcgttgc
     1861 attgacaatg ctcctatgga agggttttgg ggaattttaa aggtagaaat gtactattta
     1921 agaaaatttg atacatatga acaactagtc aatgcaatag aagattatat acattactat
     1981 aataatttta gatatcaaaa gagattaaat tctatgtctc cacttgaatt taggaaatat
     2041 ttaagtactg agatagcata atttatttta agtagctcta aaaaaattta aatatctagg
     2101 gttttatttg acgtgttctt ttttagatag taaactttaa aatatagata ttaattatat
     2161 gaatataata aaaaaagtac taatgagtta cactagtact ttataactac ttttacatat
     2221 tttaactgta taaaacagtg ggtatagttc actttttcaa atatttattc cttgccatat
     2281 taattatatc ataaatattg gaaacat
//
LOCUS       DACTZW010000180         2285 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.183, whole genome shotgun sequence.
ACCESSION   DACTZW010000180 DACTZW010000000
VERSION     DACTZW010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2285)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2285)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2285
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.183"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(<1..263)
                     /locus_tag="JAM15_19010"
     CDS             complement(<1..263)
                     /locus_tag="JAM15_19010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAT6800338.1"
                     /translation="MEKGRLLQNKNVNKAIQVSKITLIINLSLSLLKFVAGYIGKSSA
                     MLSDAVHSASDVLSTIVVMVGIKISEKQPDREHPYGHERMECVA"
     gene            complement(275..973)
                     /locus_tag="JAM15_19015"
     CDS             complement(275..973)
                     /locus_tag="JAM15_19015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002591418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6800339.1"
                     /translation="MKRILSSTIQVFKQIKSDPMMFAACFTPFVMGALIKSGIPFLER
                     ITDFSLRAHYPIFDLLLSIMAPVLLCFAFAMITLEEIDDKVSRYFSITPLGKSGYLFT
                     RLGVPSIISAIIAFIVLLLFSLEKLSIGMTICLALLGSVQAIIVSLMIITLSSNKLEG
                     MAVTKLAALTLLGIPAPFFIDSYYQFAVGFLPSFWVAKAMQDEAVLYFSIGLVVALVW
                     YYFLTKRLFRKLAG"
     gene            complement(970..1653)
                     /locus_tag="JAM15_19020"
     CDS             complement(970..1653)
                     /locus_tag="JAM15_19020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016295773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6800340.1"
                     /translation="MRLGRLICGDIHFQWKYGFYFIYFILTVLYVCGIAALTGHWKTD
                     IASIMIYSDPAAMGLFFMGAIVLLEKSQKVLNAMVVSPVKVSEYILSKTVALIAISTV
                     IALILGFVSGSNQLLSIAVGTALTSAVFTMLGIIAATKISNLNQFLIVIMPIEIVCFV
                     PPIVGLFVKLPDIFRFFPFTACMNLITGKSILLSFDMVLVIATLIILYIVARHTVKHM
                     WRSLGGVKL"
     gene            complement(1650..>2285)
                     /locus_tag="JAM15_19025"
     CDS             complement(1650..>2285)
                     /locus_tag="JAM15_19025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6800341.1"
                     /translation="RFYENIGVDFEFSTCYEKFTARQNLAYFASLYEKQPRSIDELLH
                     MVGLENDGDKKVADFSKGMRSRLNFIKALVHDPDILFLDEPTSGLDPTNNRLMKDIIL
                     AEKKRGKTIIITTHNMFDATELCDQVAFIVAGKVSALDSPHNLIMSRGAAKIHYTYYD
                     KGEKTGECLLDRTTEDKLLKSLISENRLLSIHSSEPTLNDIFVDITGRTLQ"
BASE COUNT          756 a          467 c          404 g          658 t
ORIGIN      
        1 gccacacatt ccatacgttc atgcccataa ggatgttctc tatcaggctg tttttctgat
       61 attttaattc caaccatcac aacgattgtg cttaatacat cagaagccga atgtacagcg
      121 tccgacagca tggcacttga ctttcctata tatccggcaa caaatttaag tagcgataaa
      181 ctcaggttga tgattagtgt aattttggaa acctgaatag ccttatttac atttttgttt
      241 tgcagaagtc tacctttttc cataatatgc ctccttatcc tgccagcttc cgaaacagac
      301 gttttgtaag gaagtagtac cagactagag ctaccaccaa tcctatggag aaataaagaa
      361 ccgcttcatc ctgcatggct ttcgctaccc aaaatgatgg aaggaagcca accgcgaact
      421 ggtagtaact atcaataaaa aagggggctg gtattccgag taatgtaagt gcagctagtt
      481 ttgtaactgc cataccctct aatttattgc ttgataatgt tataatcata agtgaaacaa
      541 taattgcctg tactgagccg agaagcgcca aacatattgt cattccaatg gacaactttt
      601 ctaatgaaaa aagcaacagt acaataaaag cgatgatcgc cgaaataatt gagggtactc
      661 ccaaccttgt aaagagatac cctgacttac caagaggggt aatcgaaaag taccgtgaca
      721 ctttatcgtc gatttcctct aatgtaatca ttgcaaatgc aaagcagagc aatacaggag
      781 ccatgataga aagtaataaa tcaaaaatcg gatagtgtgc tcgcaaagaa aaatctgtta
      841 ttctttcaag aaagggaata ccggatttaa tcaaagctcc catgacaaaa ggcgtaaaac
      901 aagcagcaaa catcataggg tcgctcttga tttgcttaaa tacctgtatg gtactggata
      961 atatcctttt cataacttta cacctcccaa acttctccac atatgcttaa ctgtatgtcg
     1021 cgcaactatg tagaggataa tcaacgtagc aattacaagt accatatcaa acgatagtaa
     1081 aatgcttttt ccagttatga ggttcatgca agctgtgaac ggaaaaaagc ggaatatatc
     1141 tggtaacttt acaaacagac caacgatagg tggaacaaag caaacaattt ctatcggcat
     1201 aatcacaatg agaaattggt tcaagtttga aatttttgta gccgcaataa ttccaagcat
     1261 agtaaagact gctgatgtca aagctgtacc aactgcgata ctaagtaact gattgctacc
     1321 ggaaacgaat cctaatatca gtgcaattac cgtagatatg gcaattaacg caactgtttt
     1381 tgaaagtatg tactccgata cttttacagg cgatactacc atagcattta acaccttttg
     1441 acttttttcc aagaggacaa tcgctcccat aaagaacaat cccattgctg ccgggtcaga
     1501 gtatatcatg atagaagcaa tatccgtttt ccaatgtccc gtcaaagcgg caatcccaca
     1561 cacatataaa actgttaata taaagtagat aaaatagaaa ccatatttcc attggaaatg
     1621 tatatcacca caaattaaac gtcccaatct cattgaagtg tcctccctgt aatatcaaca
     1681 aaaatatcat ttaatgtagg ctcactacta tgaatagaaa gcaaacggtt ttcggaaatt
     1741 aaacttttta acaacttatc ttctgtggtt ctatcaagga gacattctcc ggttttctcg
     1801 cctttatcat agtaggtata gtgtattttg gcagctcccc ttgacataat caaattatgc
     1861 gggctatcca atgcactgac ttttccggca acgataaagg ctacttggtc acatagctct
     1921 gttgcgtcaa acatattgtg agtagtaatg ataatcgttt ttccgcgttt cttttccgca
     1981 agaataatat ctttcattaa acgattattt gtagggtcaa gaccgcttgt aggttcatca
     2041 aggaataata tatcagggtc atggactaac gctttaatga aattcaagcg agaacgcata
     2101 cctttggaaa agtcagcaac ttttttgtcc ccgtcatttt ccaagcctac catatgcaat
     2161 aattcatcaa tagaccgagg ttgcttttca tatagagaag caaaataggc gagattttgt
     2221 cgtgctgtga atttctcgta gcaggttgaa aattcaaagt ctaccccaat attttcataa
     2281 aaccg
//
LOCUS       DACTZW010000181         2265 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.184, whole genome shotgun sequence.
ACCESSION   DACTZW010000181 DACTZW010000000
VERSION     DACTZW010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2265
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.184"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            <1..>2265
                     /locus_tag="JAM15_19030"
     rRNA            <1..>2265
                     /locus_tag="JAM15_19030"
                     /product="23S ribosomal RNA"
BASE COUNT          621 a          482 c          680 g          482 t
ORIGIN      
        1 gggacacgtg aaaccctgtg ggaagcagga gggaccaccc tccaaggcta aatactacct
       61 agtgaccgat agcgtatagt accgtgaggg aaaggtgaaa agaaccccgg gaggggagtg
      121 aaatagaacc tgaaaccctg cacttacaag ctgtggaagc acatttcttg tgtgaccgcg
      181 tactttttgt agaacgggcc aacgagttac gttaagtagc aaggttaagc acttaaggtg
      241 cggagccgta gcgaaagcga gttttaactg agcgttcagt tacttgacgt agacccgaaa
      301 ccgggcgacc tacccatgag caggatgaag cgaaagtaaa atttcgtgga ggtccgaacc
      361 cacgagcgtt gaaaagctcg gggatgactt gtgggtagcg gtgaaattcc aatcgagccc
      421 ggagatagct ggttctcccc gaaatagctt tagggctagc ctcaaggtga gagatacgga
      481 ggtagagcac tgaatgtcct agggggtatt gcacctaccg aagactatca aactccgaat
      541 gccgtcatct tatacttggg agtcagactg tgggtgataa gattcatagt cgaaagggca
      601 acagcccaga tcgtcagcta aggtccctaa atgtaagtta agtggtaaag gatgtgggat
      661 tgcacagaca accaggatgt tggcttagaa gcagccactc attcaaagag tgcgtaatag
      721 ctcactggtc gagtgatcct gcgccgaaga tttccggggc taaaacttac taccgaagct
      781 acggcatcag taatgatggg taggggagct tcccatacgg gttgaagcat gaccgtaagg
      841 acatgtggac agtatgggag tgagaatgtt ggcatgagta gcgagatgtg ggtgagaatc
      901 ccacaggccg taaacccaag gtttccaggg gaaggttcgt ccgccctggg ttagtcggga
      961 cctaagctga ggccgaaagg cgtaggtgat ggacaacagg ttgatattcc tgtactaccg
     1021 ataaccgttt gagagaaggg atgacacagt aggataagct aagcacactg ttggttatgt
     1081 gtgcccaagc attgaggcag tcaaagtagg caaatccgct ttgataatgc tgggatgtga
     1141 tggggagcga aatttagtag cgaagtagct gatttcacac tgtcaagaaa agtctctatc
     1201 gaggttaaag gtacccgtac cgcaaaccga cacaggtggg tgaggagagt atcctaaggc
     1261 cagcgagaga actgttgtta aggaactcgg caaaatgacc ccgtaactta gggataaggg
     1321 gtgccaccat caggtggccg cagagaatag gcccaagcga ctgtttacca aaaacatagg
     1381 tttctgctaa gtcgcaagac gatgtatagg agctgacgcc tgcccggtgc tggaaggtta
     1441 aggggatctg ttagagcaat cgaagcagtg aacttaagcc ccagtaaacg gcggccgtaa
     1501 ctataacggt cctaaggtag cgaaattcct tgtcgggtaa gttccgaccc gcacgaaagg
     1561 cgtaacgatt tgggcactgt ctcaacaaca gactcggtga aattgtaatt ccggtgaaga
     1621 tgccggatac ctgcgacagg acggaaagac cccatggagc tttactgtag cttgacattg
     1681 ggtcttggta ctacatgtac aggataggtg ggaggctttg aaaccaggac gccagttttg
     1741 gcggagccat ccttgggata ccacccttgt agtactggga ctctaaccat aggccatgaa
     1801 tctggtcttg ggacactgtc aggtgggcag tttgactggg gcggtcgcct cccaaaaggt
     1861 aacggaggcg ctcaaaggtt ctctcagtac ggtcggaaat cgtacgtaga gtgtaaaggc
     1921 aaaagagagc ttgattgcaa gacatacagg tcgagcaagg atgaaaatcg gacttagtga
     1981 tccggtggtt ctgcgtggaa gggccatcgc tcaacggata aaagctaccc tggggataac
     2041 aggcttatct cccccaagag tccacatcga cggggaggtt tggcacctcg atgtcggctc
     2101 atcacatcct ggggctgtag taggtcccaa gggttgggct gttcgcccat taaagtggta
     2161 cgcgagctgg gttcagaacg tcgtgagaca gttcggtccc tatccgtcgc aggcgtagga
     2221 aatttgagaa gacctgtcct tagtacgaga ggaccgggat ggacg
//
LOCUS       DACTZW010000182         2230 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.185, whole genome shotgun sequence.
ACCESSION   DACTZW010000182 DACTZW010000000
VERSION     DACTZW010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2230)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2230)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2230
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.185"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            894..1361
                     /locus_tag="JAM15_19035"
     CDS             894..1361
                     /locus_tag="JAM15_19035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HAT6800342.1"
                     /translation="MITKFFSNILSVFLYFLLSLLGVAGIIFLCMIPMFLYDFSSDKV
                     IALIARILYFSDYFIVILFLIFIINSTKYSPFILENVKRFKVMGCCLLINTIIECVIG
                     YNSNTSLIMIFGDNSGGISPLMVISFIFALMCFVIAETFDKAIKIKEDNDLTI"
     gene            1372..1587
                     /locus_tag="JAM15_19040"
     CDS             1372..1587
                     /locus_tag="JAM15_19040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAT6800343.1"
                     /translation="MAIVVNLDVMMAKRKISLKDLAEKIDITNANLSILKTGKAKAIR
                     FTTLNEICKALDCQPGDILEYVEDEND"
BASE COUNT          848 a          249 c          232 g          901 t
ORIGIN      
        1 agtattaata attttttaat aattagttat tatagaaaaa agagggatat aatattgtct
       61 ccctctcttt cttctgtaat attatataat ttttatttat cactctcaat aaattatagt
      121 tatctacaaa attcaatctt taatacatta ttaatatatt gtgatattaa tattacagta
      181 ttaaataaaa tctaataaaa ttaactataa aatatctatt atataaatat ccactcttat
      241 gtttgaaatc tgtcatatag ttttatcctt cttatctttt atatcaataa ctttttttaa
      301 taaaattgac aaaacaaagt aaaaaacctt attgataatg aaacaaatga tactataagt
      361 tctgatatta tagtaattgc atataaatag acatcataac aataatataa tattgtcact
      421 ataaaattaa atgtaaaaat ctccaatcta actaaataca catataggta ttttttaagt
      481 ttttaggtat ttcttctgaa aatgatttat tgattgatac caatttacat aatcttttta
      541 atataaacaa tgatacaata tatgggacag cacatatgta tatagctact tatattacat
      601 attacagttg gcatattcgt atttgtaatg cttataccaa ttttaaaata caccatcagt
      661 actaatggca ttaaaataat ctataataaa gttaaaatta ttccaattag tacaatatta
      721 tttaatattt tacaactcat attctttttt atataaattt accaccttat acattcttat
      781 ttttagtgta tattataatg gttttatata ttatatcaac aatttattat tgaaattcaa
      841 taaattatat attataatca ataatatact ttatataaag gagatgatat tttatgatta
      901 caaaattttt tagtaatata ttatcagtat ttctatattt tctattatca cttttaggag
      961 ttgctggtat aatattctta tgtatgatac ctatgttttt atatgatttt agttctgaca
     1021 aagtaatcgc tttaattgca agaatactat atttttctga ctactttata gtcatcttat
     1081 tcttgatatt tataattaat agtactaagt attccccatt catacttgaa aatgtaaaaa
     1141 ggtttaaagt aatgggatgt tgtttattga taaacactat aattgaatgt gtaattggtt
     1201 ataactcaaa tactagtctt ataatgatat ttggagataa tagtggcggt atctcaccac
     1261 ttatggttat ttcttttata tttgcactaa tgtgctttgt aattgcagaa acatttgata
     1321 aagctataaa aataaaagaa gataatgatt taacgatata gaggtgatgt tatggcaata
     1381 gtagttaacc tagatgtaat gatggcaaaa aggaaaatat cacttaaaga tttggcagaa
     1441 aaaatagata ttacaaatgc aaatttatca attttaaaaa ctggaaaagc aaaagctatt
     1501 agatttacca ctctaaacga aatttgcaaa gctttagact gtcagccagg tgatatactt
     1561 gaatatgtag aagatgaaaa tgattaaaaa agagtgttta gaaacactct tttttattat
     1621 actatatgat ttttattctt ttactatatt attgacatta atattaactt tgtttaaagt
     1681 cataacaaaa tacgttctaa gaaagaaact gttccttttt ctatttgtta tccattacct
     1741 ataagaactg tatcacacta aatcatactt ttaaattgat aattttgcca cagattccta
     1801 tatacattct tttctaccta atatttattt aaactgttag caaaacatgg aactttttca
     1861 tttacttata cctccattta tattatttca tagtttatag ctacgtgtta taaattacat
     1921 tattgatgat ttatctaaca tttgtaatct tttagatact ctttgaagtt acaacactgt
     1981 tatactctaa ttaagtaaac taaatctgat acaagttggt gattatatga aaagaaaact
     2041 ttcaacctat tttaaaggat atattttagg tttatgtata gcatttttat tatttacttt
     2101 tatattaaaa aaattaatta tagaaaatat cattggaata ataattggaa ctggaattgc
     2161 atttttactg atttacctat ttaataaaaa aagaaaataa tattctataa aaaggtcttt
     2221 tagtgaattt
//
LOCUS       DACTZW010000183         2138 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.186, whole genome shotgun sequence.
ACCESSION   DACTZW010000183 DACTZW010000000
VERSION     DACTZW010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2138)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2138)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2138
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.186"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            156..605
                     /locus_tag="JAM15_19045"
     CDS             156..605
                     /locus_tag="JAM15_19045"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800344.1"
                     /translation="MSLIKYRGYDFENEKWIYSATIMWSDAVDCLFMLKEDCEWQKVS
                     NIGVFSKCWSGNNEEIYEGDILKEPYNTKNKYEYGIVRQENYALGLYVEWHYLKQFEG
                     KWEELTSKATIMNSKEYIVVGNECENLEEVRKEFLECKEMLENEHLG"
     gene            997..1686
                     /locus_tag="JAM15_19050"
     CDS             997..1686
                     /locus_tag="JAM15_19050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800345.1"
                     /translation="MDLNKIMNDALVDLEENGFVEEIVKKQLAETIKRVVNEVFGNWG
                     DFSKKIEKHLSENININLDKLDIQKYNVLVATTVKEKIDMTMKVEAIEHLKRNLDNML
                     VGAEKEYKMSELLEILKMDKYDIDEYEGYEDCITFILDENKYGSGWIEIDKEPNKSKY
                     RCEHSILLRKDGTIASYRYENREISSKDIMSGFDNFGDLLFKIFAHGSKIILDLGNDI
                     EDYDLTNGEDY"
     gene            1704..1925
                     /locus_tag="JAM15_19055"
     CDS             1704..1925
                     /locus_tag="JAM15_19055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800346.1"
                     /translation="MSKYVLRWQKGLLLDERKINYSCGSKEMLKKKAELLAKDDKILL
                     VTIDKVEEVIKDTRSQKMAEYYCDGGIEI"
     gene            1922..>2138
                     /locus_tag="JAM15_19060"
     CDS             1922..>2138
                     /locus_tag="JAM15_19060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HAT6800347.1"
                     /translation="MIIHKFIIHVLDKNSDTPILNDFEGRVSQDMDIFFQKKINKVLR
                     DNDIRKAVFNDYSSNLIKKCCEQIIYDE"
BASE COUNT          921 a          146 c          441 g          630 t
ORIGIN      
        1 tatattcaag aggtgacaga tggtattagc aaatgtggaa caagtaatta agttagctga
       61 aaagatatta aataagaaaa agtgttctgt taataaagct attgatatag ctataaaaat
      121 attaagtaaa tatgagtgcg aggggatgtt aagaaatgag tctaattaag tacagaggtt
      181 atgattttga gaacgaaaag tggatttatt cagcaacaat aatgtggagt gatgcagtag
      241 attgtttatt tatgttgaaa gaagattgtg aatggcaaaa agtatctaat attggagtat
      301 tctctaaatg ttggtctgga aataatgaag aaatttatga gggagatata ttgaaagaac
      361 cttataatac taaaaataaa tatgaatatg gaatcgtaag acaagaaaat tatgctcttg
      421 gattatatgt tgaatggcat tatttaaagc aatttgaagg taaatgggag gagcttacaa
      481 gtaaggcaac tataatgaat agcaaagaat atatagtagt tggtaatgaa tgcgagaatt
      541 tagaagaagt tagaaaagag tttttagaat gtaaggagat gttagaaaat gaacatcttg
      601 gctagtttaa tacttatagt aggtagtttt ataggtggta gagtttatga gtatagattg
      661 aatctgaaag agtgtgaaaa ttgcgacaat aaaagaggta tataagaatg gatgatagat
      721 tagaaatgat aaatgcttct gtaaattata tacagatgat atgtgaaagt tcaaatatag
      781 ctattatagc agagcgagga agagttagaa tattagattt agaaactaaa gaaaaatatg
      841 atttattaaa aaataaactc gaggaaatgt tagaagaaat ataagtgaaa atatctaatt
      901 aaaacagttt agagagttgc aaaatgtctt ttaatataat tactgttgaa gtgttttgcg
      961 actcttaaaa atgaaaatag agaggggaat aatacaatgg atttaaataa aattatgaat
     1021 gatgcactag tagacttaga ggaaaatggt tttgtagagg aaatagttaa aaaacaattg
     1081 gcagagacaa taaaaagagt tgtgaatgag gtttttggaa attggggtga ttttagtaaa
     1141 aagattgaaa agcatctaag tgaaaatata aatataaatt tagataaatt agatatacaa
     1201 aaatataatg tgcttgtagc aactacagta aaagaaaaga ttgatatgac aatgaaggta
     1261 gaagctattg aacacttaaa aagaaatttg gataacatgc ttgtaggtgc cgaaaaagaa
     1321 tataaaatga gcgaattgtt ggaaatatta aaaatggata aatatgatat tgatgaatat
     1381 gaaggctatg aagattgcat aacatttatt cttgatgaaa ataaatatgg ttcgggatgg
     1441 attgaaattg ataaagaacc aaataaaagt aaatacagat gcgaacactc catattgttg
     1501 agaaaagatg gaactattgc atcatataga tacgagaata gagaaatatc atctaaagat
     1561 ataatgagtg gatttgataa ttttggagat ttgctattta aaatatttgc tcatgggtca
     1621 aaaataattt tggatttagg aaatgatata gaagattatg atttaacaaa tggagaagat
     1681 tattaaaata ggggatggaa caaatgtcaa agtatgtatt gagatggcaa aaaggattat
     1741 tactagatga acgcaagata aattattcat gtggaagtaa agaaatgtta aaaaagaaag
     1801 ctgaattatt agctaaagat gacaagatat tacttgtaac aatagataaa gttgaagaag
     1861 ttataaaaga tactagaagc caaaaaatgg ctgaatatta ttgcgatgga ggaattgaaa
     1921 tatgataata cacaaattta taatacatgt tttagataag aatagcgata caccaatact
     1981 aaatgatttt gaaggtagag ttagtcaaga tatggacata ttctttcaaa agaaaatcaa
     2041 caaagtatta agagataatg acatcagaaa agcagtattt aatgactata gtagcaatct
     2101 gattaagaaa tgttgtgaac agataatata tgatgaaa
//
LOCUS       DACTZW010000184         2061 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.187, whole genome shotgun sequence.
ACCESSION   DACTZW010000184 DACTZW010000000
VERSION     DACTZW010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2061)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2061)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2061
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.187"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(<1..156)
                     /locus_tag="JAM15_19065"
     CDS             complement(<1..156)
                     /locus_tag="JAM15_19065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAT6800348.1"
                     /translation="MKKGRLLQNKNVNKAIQVSKITLIINLSLSLLKFAAGYIGKSSA
                     MLSDAVHS"
     gene            complement(168..866)
                     /locus_tag="JAM15_19070"
     CDS             complement(168..866)
                     /locus_tag="JAM15_19070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002591418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6800349.1"
                     /translation="MKRILSSTIQVFKQIKSDPMMFAACFTPFVMGALIKFGIPFLER
                     ITDFSLQTYYPIFDLLLSIMAPVLLCFAFAMITLEEIDDKVSRYFSITPLGKSGYLFT
                     RLGVPSIISAVIAFIVLLLFSLEKLSIGMTICLALLGSVQAIIVSLMIITLSSNKLEG
                     MAVTKLAALTLLGIPAPFFIDSYYQFSVGFLPSFWVAKAMQNETVLYFSIGLMVALVW
                     YYFLTKRLFRKLAG"
     gene            complement(863..1546)
                     /locus_tag="JAM15_19075"
     CDS             complement(863..1546)
                     /locus_tag="JAM15_19075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016295773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6800350.1"
                     /translation="MRLGRLICGDIHFQWKYGFYFIYFILTVLYVCGIAALTGHWKTD
                     IASIMIYSDPAAMGLFFMGAIVLLEKSQKVLNAMVVSPVKVSEYILSKTVALIAISTV
                     IAMILGFVSGSNQLLSIAVGTALTSAIFTMLGIIAATKISNLNQFLIVIMPIEIVCFV
                     PPIVGLFVKLPDIFRFFPFTACMNLITGKSILLSFDMVLVIATLIILYIVARHTVKHM
                     WRSLGGVKL"
     gene            complement(1543..>2061)
                     /locus_tag="JAM15_19080"
     CDS             complement(1543..>2061)
                     /locus_tag="JAM15_19080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6800351.1"
                     /translation="DELLHMVGLENDGDKKVADFSKGMRSRLNFIKALVHDPDILFLD
                     EPTSGLDPTNNRLMKDIILAEKKRGKTIIITTHNMFDATELCDQVAFIVAGKVSALDS
                     PHNLIMSRGAAKIHYTYYDKGEKTGECLLDRTTEDKLLKSLISENRLLSIHSSEPTLN
                     DIFVDITGRTLQ"
BASE COUNT          692 a          412 c          360 g          597 t
ORIGIN      
        1 cgaatgtaca gcgtccgaca gcatggcact tgactttcct atatatccgg cagcaaattt
       61 aagtagcgat aaactcaggt tgatgattag tgtgattttg gaaacctgaa tagccttatt
      121 tacatttttg ttttgcagaa gtctaccttt tttcataata tgccttctta tcctgccagc
      181 ttcctaaaca gacgttttgt aaggaagtag taccagacta aagctaccat caatcctatg
      241 gagaaataaa gaaccgtttc attctgcatg gctttcgcta cccaaaatga tggaaggaag
      301 ccaaccgaga actggtaata actatcaata aaaaagggag ctggtattcc gagtaatgta
      361 agtgcagcta gttttgtaac tgccataccc tctaatttat tgcttgataa tgtgataatc
      421 ataagtgaaa caataattgc ctgtactgag ccgagaagcg ccaaacatat tgtcattcca
      481 atggacaact tttctaatga aaaaagcaac agtacaataa aagcgatgac cgccgaaata
      541 attgagggta ctcccaacct tgtaaagaga taccccgact taccaagagg ggtaatcgaa
      601 aagtaccgtg acactttatc gtcgatttcc tctaatgtaa tcattgcaaa tgcaaagcag
      661 agcaatacag gagccatgat agaaagtaat aaatcaaaga tcggatagta tgtttgcaaa
      721 gaaaaatctg ttattctttc aagaaaggga ataccgaatt taatcaaagc tcccatgaca
      781 aaaggcgtaa aacaagctgc aaacatcata gggtcgctct tgatttgctt aaatacctgt
      841 atggtactgg ataatatcct tttcatagct ttacacctcc caaacttctc cacatatgct
      901 taactgtatg tcgcgcaact atgtagagga taatcaacgt agcaattaca agtaccatat
      961 caaacgatag taaaatgctt tttccagtta tgaggttcat gcaagctgtg aacggaaaaa
     1021 agcggaatat atctggtaac tttacaaaca gaccaacgat aggtggaaca aagcaaacaa
     1081 tttctatcgg cataatcaca atgagaaatt ggttcaagtt tgaaattttt gtagccgcaa
     1141 taatgccaag catagtaaag attgctgatg tcaaagctgt accaactgcg atactaagta
     1201 actgattgct accggaaacg aatcctaata tcattgcaat taccgtagat atggcaatta
     1261 acgcaactgt ttttgaaagt atgtactccg atacttttac aggcgatact accatagcat
     1321 ttaacacctt ttgacttttt tccaagagga caatcgctcc cataaaaaac aatcccattg
     1381 ctgccgggtc agagtatatc atgatagaag caatatccgt tttccaatgt cccgtcaaag
     1441 cggcaatccc acacacatat aaaactgtta atataaagta gataaaatag aaaccatatt
     1501 tccattggaa atgtatatca ccacaaatta aacgtcccaa tctcattgaa gtgtcctccc
     1561 tgtaatatca acaaaaatat catttaatgt aggctcacta ctatgaatag aaagcagacg
     1621 gttttcggaa attaaacttt ttaacaactt atcttctgtg gttctatcaa gcagacattc
     1681 tccggttttc tcgcctttat catagtaggt atagtgtatt ttggcagctc cccttgacat
     1741 aatcaaatta tgtggactat ccaatgcact gacttttccg gcaacaataa aggctacttg
     1801 gtcacatagc tctgttgcgt caaacatatt gtgagtagta atgataatcg tttttccgcg
     1861 tttcttttcc gcaagaataa tatctttcat taaacgatta tttgtagggt caagaccgct
     1921 tgtaggttca tcaaggaata atatatcagg gtcatggact aacgctttaa tgaaattcaa
     1981 gcgagaacgc atacctttgg aaaagtcagc aacttttttg tccccatcat tttctaagcc
     2041 taccatatgc aataattcat c
//
LOCUS       DACTZW010000185         2005 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.188, whole genome shotgun sequence.
ACCESSION   DACTZW010000185 DACTZW010000000
VERSION     DACTZW010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2005
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.188"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            4..1932
                     /locus_tag="JAM15_19085"
     CDS             4..1932
                     /locus_tag="JAM15_19085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HAT6800352.1"
                     /translation="MVWHIEYEIFSAIIVIFLMVYFFRSKFIPTLQNKIYCALLIFSF
                     LFILSNILGSFCLNNIDKIPIFITFLLNQIYLLLLPIPAALVSFYVMAIIYQDIRYMK
                     KRLLFLSIPLIICIILSITNPFTHILFGLSKETGYIRGCGYVATFASFFFYAIYSAFL
                     SFKYRKAMHESKIWAIRGFLIVSIVAIILQAIFLQYLLTGTACACSLLLTYLSMQNRG
                     LIIDDLTGVLNRQSFIQELDLNINTEQSGFIITIALDDFKFMNETFGTKNGDIALKEV
                     GKYLIQIHDVNHVYRIGGDIFSIVVNSQLGIEPDDIIRKIEERFKKPWLVEEISFNLA
                     TSISVVYYPENAETTEDVIVAIDFSIHEAKRSESRRVVYADASISEKIKKKHVIKNCL
                     KEALKNDGFEVYYQPIFSNSRGRFTSAEALLRLEHKELGFIPPDEFIPIAEQTGLINS
                     IGLVVFEKVCRFIASDEFENLKLDNIAVNLSVVQCMQKNLADDLLYLMNKYNVSPTKF
                     KLEITETVAMGSFNIIKETMERLIDLGVKFALDDFGIAYSGVTNMLSLPFSVIKLDKS
                     LIWSMNEDSRHKLTVETIIALINKLNMKAVAEGVETIKCAEDLIAMECEYLQGYYFSK
                     PVPEDVFKNLLKENTFTS"
BASE COUNT          692 a          231 c          333 g          749 t
ORIGIN      
        1 tttatggtat ggcatataga atatgagatt ttttctgcaa ttatagttat ttttttaatg
       61 gtatactttt ttagaagtaa atttatacct actttacaaa acaaaatata ttgtgcactt
      121 ttaatattct catttttatt tatactttca aatattttag gttcattttg tctaaataat
      181 atagacaaaa ttccaatttt tattactttt ttattgaatc agatatactt attgttattg
      241 ccaataccag cagctcttgt atcattttat gttatggcta ttatttatca agatataagg
      301 tatatgaaaa aaagattatt atttttatct ataccactta taatttgtat aatcttatct
      361 attacaaatc cttttacgca tattctattt ggattgtcaa aagaaacagg ttatatacgg
      421 ggttgtggat atgttgcaac ttttgcatct tttttctttt atgcaatata ttcagcattt
      481 ttatctttta aatatagaaa agcaatgcat gaatcaaaaa tatgggctat tagaggtttt
      541 cttatagttt caattgtggc aattatctta caggcaattt ttttacagta tcttcttaca
      601 ggaactgcat gtgcatgtag tttacttttg acatatcttt ctatgcagaa tcgaggtctt
      661 attattgatg accttactgg tgtactcaat agacaatctt ttattcaaga gctagatttg
      721 aatatcaata ctgaacaatc aggatttatt attacaattg cgcttgatga ttttaagttt
      781 atgaatgaaa cttttggaac aaaaaatgga gatattgcac taaaagaagt tggaaaatat
      841 ttgattcaga tacatgatgt aaaccatgta tatagaatag ggggagatat attttctatt
      901 gttgtcaata gtcaattagg tatagaacca gatgatatta tcagaaagat agaagaaaga
      961 tttaaaaagc cttggctagt agaagagata agttttaatt tagcaactag tatttctgtt
     1021 gtttattacc cagaaaatgc agaaacgaca gaagatgtaa ttgttgctat agatttctct
     1081 atacatgaag caaaacgttc tgagtcaagg cgagttgttt atgcagatgc gtctataagt
     1141 gaaaagataa agaagaaaca tgttattaaa aattgtttaa aagaagcatt aaaaaatgat
     1201 gggtttgaag tgtactacca acctatattt tctaatagca ggggcaggtt tacttcagca
     1261 gaggcattac ttaggctaga acacaaagag ttaggtttta tacctcctga tgaatttatt
     1321 ccaattgcag aacaaacagg attgattaac tcaattggat tagtagtctt tgagaaggta
     1381 tgtagattta tagctagtga tgagtttgaa aatttaaaat tggataatat agctgtgaat
     1441 ctttctgtag tacaatgtat gcaaaaaaac ttagctgatg atttacttta tcttatgaat
     1501 aaatataatg tatcaccaac taaatttaaa cttgaaatta ctgagactgt ggctatgggc
     1561 tcttttaata taattaaaga aacaatggaa agattaattg atttaggtgt taagtttgca
     1621 cttgatgatt ttggaattgc ttattctgga gttactaata tgctttcttt accattttca
     1681 gtaattaagt tagataagag tttgatttgg tctatgaatg aagatagtag gcataagctt
     1741 acagttgaga cgattatagc tcttataaat aaattgaata tgaaggctgt agcagaaggt
     1801 gttgaaacca ttaagtgtgc tgaagattta atagctatgg agtgtgaata tttgcaaggg
     1861 tattattttt ctaaaccagt tccagaagat gtttttaaaa atttgttgaa agaaaatact
     1921 tttacaagtt aacacccttt atttttttaa ttacaacttt gttcattgac actgccagcg
     1981 atatattata aaattaacac aataa
//
LOCUS       DACTZW010000186         1979 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.189, whole genome shotgun sequence.
ACCESSION   DACTZW010000186 DACTZW010000000
VERSION     DACTZW010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1979
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.189"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            76..192
                     /gene="rrf"
                     /locus_tag="JAM15_19090"
     rRNA            76..192
                     /gene="rrf"
                     /locus_tag="JAM15_19090"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            199..273
                     /locus_tag="JAM15_19095"
     tRNA            199..273
                     /locus_tag="JAM15_19095"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:231..233,aa:Asn,seq:gtt)
     gene            278..352
                     /locus_tag="JAM15_19100"
     tRNA            278..352
                     /locus_tag="JAM15_19100"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:311..313,aa:Glu,seq:ttc)
     gene            358..433
                     /locus_tag="JAM15_19105"
     tRNA            358..433
                     /locus_tag="JAM15_19105"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:391..393,aa:Val,seq:tac)
     gene            439..515
                     /locus_tag="JAM15_19110"
     tRNA            439..515
                     /locus_tag="JAM15_19110"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:473..475,aa:Asp,seq:gtc)
     gene            526..600
                     /locus_tag="JAM15_19115"
     tRNA            526..600
                     /locus_tag="JAM15_19115"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:558..560,aa:Thr,seq:tgt)
     gene            615..699
                     /locus_tag="JAM15_19120"
     tRNA            615..699
                     /locus_tag="JAM15_19120"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:649..651,aa:Tyr,seq:gta)
     gene            709..782
                     /locus_tag="JAM15_19125"
     tRNA            709..782
                     /locus_tag="JAM15_19125"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:741..743,aa:Gly,seq:tcc)
     gene            793..869
                     /locus_tag="JAM15_19130"
     tRNA            793..869
                     /locus_tag="JAM15_19130"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:827..829,aa:Arg,seq:tct)
     gene            879..954
                     /locus_tag="JAM15_19135"
     tRNA            879..954
                     /locus_tag="JAM15_19135"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:912..914,aa:Gln,seq:ttg)
     gene            966..1041
                     /locus_tag="JAM15_19140"
     tRNA            966..1041
                     /locus_tag="JAM15_19140"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:999..1001,aa:Lys,seq:ttt)
     gene            1044..1132
                     /locus_tag="JAM15_19145"
     tRNA            1044..1132
                     /locus_tag="JAM15_19145"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1078..1080,aa:Ser,seq:tga)
     gene            1150..1240
                     /locus_tag="JAM15_19150"
     tRNA            1150..1240
                     /locus_tag="JAM15_19150"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1184..1186,aa:Ser,seq:gct)
     gene            1249..1325
                     /locus_tag="JAM15_19155"
     tRNA            1249..1325
                     /locus_tag="JAM15_19155"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1283..1285,aa:Pro,seq:tgg)
     gene            1411..1486
                     /locus_tag="JAM15_19160"
     tRNA            1411..1486
                     /locus_tag="JAM15_19160"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1444..1446,aa:Trp,seq:cca)
     gene            1547..1623
                     /locus_tag="JAM15_19165"
     tRNA            1547..1623
                     /locus_tag="JAM15_19165"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1581..1583,aa:Pro,seq:tgg)
     gene            1630..1706
                     /locus_tag="JAM15_19170"
     tRNA            1630..1706
                     /locus_tag="JAM15_19170"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1664..1666,aa:Ile,seq:gat)
     gene            1710..1785
                     /locus_tag="JAM15_19175"
     tRNA            1710..1785
                     /locus_tag="JAM15_19175"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1743..1745,aa:Phe,seq:gaa)
     gene            1793..1869
                     /locus_tag="JAM15_19180"
     tRNA            1793..1869
                     /locus_tag="JAM15_19180"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1827..1829,aa:Met,seq:cat)
BASE COUNT          517 a          449 c          529 g          484 t
ORIGIN      
        1 aaaaaaataa aaaaagtatt gacaaaaata gtaaaaaatg ttaatattat acttgtccta
       61 gcaacaagaa aaaaatgtgg ttataatagc ggagaagata cacctgtttc cattccgaac
      121 acagaagtta agttctctag cgctgatggt acttggtggg aaactgcctg ggagagtagg
      181 acatagccac gtgaatgttc caaggtagct caacggtgga gcaaccggct gttaaccggt
      241 aggctgtggg ttcgagcccc acccttggag ccattatggc tcgttggtca agaggttaag
      301 acaccgccct ttcacggcgg taacaggggt tcaattcccc tacgagtcac catttgtggg
      361 atcatagctc agctgggaga gcacctgcct tacaagcagg gggtcacagg ttcgagtcct
      421 gttggtccca ccatttgcgg cctggtagtt cagttggtta gaatgccagc ctgtcacgct
      481 ggaggtcgag ggttcgagcc ccttccaggt cgccaaaata aaaatgctgg tgtggctcaa
      541 cggtagagca gctgacttgt aatcagcagg ttgtaggttc gattcctatc accagctcca
      601 tgtaaaacta atacggagga tttcccgagc ggccaaaggg ggcagactgt aaatctgttg
      661 tcatcgactt cggtggttcg aatccaccat cctccaccaa ttaaatatgc gggtgtagct
      721 caatggtaga gttctggcct tccaagccag ctgtgagggt tcgatcccct tcacccgctc
      781 caaagaaagc gtgggtgcat agctcagctg gatagagcaa cgcccttcta aggcgtgtgt
      841 ccggggttcg aatccctgtg cgctcaccac atatatattg gggattagcc aagtcggtaa
      901 ggcacatgac tttgactcat gtatgcgtag gttcgagtcc tgcatcccca gccaaataaa
      961 aatatggtct attagctcag tcggtagagc acctgacttt taatcagggt gtcccgcgtt
     1021 cgagtcgcgg atagatcacc aatggagagg tgtccgagtg gtttaaggag ctggtcttga
     1081 aaaccagtga cttcgaaagg ggccgtgggt tcgaatccca ccctctccgc caaaaaaatg
     1141 actgaatttg gagaagtact caagtggctc aagaggatcc cctgctaagg gattaggctg
     1201 ggtaaccggt gcgagggttc gaatccctcc ttctccgcca ttcaaaaacg aggtgtagcg
     1261 cagtttggta gcgcacatgg tttgggacca tggggccggg ggttcgagtc ccttcacctc
     1321 gaccaactta agcttttagt tcagttggtt agagtgccca actcatggct agtaattcta
     1381 gggtttgagt ccatgaaggt tattcttcat aggggtgtag ctcagttggt agagcgtcgg
     1441 tctccaaaac cgtgcgccgg gggttcgagt ccctccaccc ctgccaaata aaaaggactt
     1501 gaaaaaagtt ggattttaga gtagtataag atagtaaata agatttcgag gtgtagcgca
     1561 gtttggtagc gcacatggtt tgggaccatg gggccggggg ttcgagtccc ttcacctcga
     1621 ccaagaaaag ggcctatagc tcaggtggtt agagcgcacg cctgataagc gtgaggtcgc
     1681 tggttcgagt ccagctaggc ccaccatttg cccagatagc tcagtcggta gagcagggga
     1741 ctgaaaatcc ccgtgtcggt ggttcgattc cgcctctggg caccagaaat acggcggtat
     1801 agcttagttg gctagagcgt tcggttcata cccgaaaggt cataggttcg actcctatta
     1861 ccgctaccat ctaactatat caataaagaa ctttgaaaat taaacagtag gttaatttat
     1921 aaaacaagaa acaaaccata aagccagata ttttgataac aatagtatct gagcctgat
//
LOCUS       DACTZW010000187         1974 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.190, whole genome shotgun sequence.
ACCESSION   DACTZW010000187 DACTZW010000000
VERSION     DACTZW010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1974)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1974)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1974
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.190"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            <1..423
                     /gene="tnpB"
                     /locus_tag="JAM15_19185"
     CDS             <1..423
                     /gene="tnpB"
                     /locus_tag="JAM15_19185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family element transposase accessory
                     protein TnpB"
                     /protein_id="HAT6800353.1"
                     /translation="ARLKVARLQEHIANQRNDFLQKLSTKLIKENDIICIEDLQVKNM
                     IRNRKLSRSISDVSWSEFIRQLEYKANWHGRQIVKVGKFFASSQICNKCGYKNEEVKN
                     LNIREWICPSCNETHDRDINASINILKEGLRLITIQNK"
     gene            488..730
                     /locus_tag="JAM15_19190"
                     /pseudo
     CDS             488..730
                     /locus_tag="JAM15_19190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901211.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            733..1929
                     /locus_tag="JAM15_19195"
     CDS             733..1929
                     /locus_tag="JAM15_19195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6800354.1"
                     /translation="MLKTNNLSVGYNNKVVISNINVEVKNGEILCLLGSNGAGKTTLL
                     RSLSKLISPIKGEIYLNGVNINCISRKALSKKMALVLTNRLLGDLMTVQDIVNIGRYP
                     YTGFFGSLSKKDLIMVDEALESVDALHLKKRYFDELSDGEKQKVLVARALVQEPEIII
                     LDEPTTHLDIKHRLELINILKKLSKEKSISVILSLHEIDIALKSCDKVALIKNNKVIA
                     YGQPEDVVDEDIINSLYELDDKNFNSLLGSVEISNKSKNEVFIIGGGGKATPIYRAFT
                     KKGIGLYSGIIHENDIDYEIGRTMGIKMFTENPFEPISDESFDLAIRNLNDSKIIIDT
                     GFSVGETNKRNIDIIKEALKLDKKVYSFRNRDESKKYYDSLDSKIEHIDKVSQIINSA
                     DINNLL"
BASE COUNT          808 a          191 c          372 g          603 t
ORIGIN      
        1 gcaagattaa aagttgcaag acttcaagaa catatagcta atcaaagaaa tgattttctg
       61 caaaaactat ctactaaatt aataaaagag aacgatatta tttgcataga agatttacaa
      121 gtaaagaata tgattagaaa tcgtaaacta tctcgctcaa tttctgatgt gtcatggtca
      181 gagtttattc gtcaattaga atacaaggct aattggcatg gtagacaaat tgtaaaggta
      241 ggtaaattct ttgcaagttc acaaatatgt aataaatgtg ggtataaaaa cgaggaagtg
      301 aagaacttaa atataagaga atggatttgt cctagttgta atgaaactca cgatagagat
      361 ataaatgcaa gtataaatat attaaaagaa ggattaagac taataacaat tcaaaataaa
      421 taacgtatat aagaaccgta ggaactatgg ggatagcctg tggagaatta gtaagacata
      481 ttttagtatg taaaattcta tgaagcagga accctgtgac tttagtcatg ggaggttcag
      541 atttaaaaca tcagataata gagttttgat accagtagta atatttttag gcagtatagt
      601 tacagctctt tgtgatttaa tatcaagagt aattttatca ccagtagaat taccaataag
      661 tacgataaca tctttattag gagctccaat tgtagtaatg ttattggtga aaaggaagga
      721 tagggcttag acatgttgaa aactaataat ttaagtgtag gatacaataa caaagttgtt
      781 ataagtaata taaatgtaga agtaaaaaat ggagaaatac tatgtctttt gggaagtaat
      841 ggagctggaa aaactaccct attaaggtcc ttatctaaac ttatatcacc aataaaaggt
      901 gaaatatatt tgaatggtgt aaacataaat tgtatatcaa gaaaagcatt atcaaaaaaa
      961 atggctttag tacttacaaa tagattatta ggtgatttaa tgactgtaca agatatagtc
     1021 aatataggaa ggtatccata tacaggattt tttgggagtc tatctaagaa agatttaata
     1081 atggtagatg aagcactgga gtctgtagat gccttacatt taaagaaaag atattttgat
     1141 gaactaagtg atggagaaaa acaaaaggtg ttggttgcaa gagctcttgt tcaagaacca
     1201 gaaataatta tattagatga gcctacaact cacttggata taaaacatag attggaactc
     1261 ataaacatac tgaaaaaatt aagtaaagaa aagtcaatat cagtaatact ttcattgcat
     1321 gaaatagaca tagcattaaa aagttgtgat aaagttgctc ttataaaaaa taataaagtc
     1381 atagcttatg gtcagcctga agatgtagta gatgaggata ttataaattc gctttatgaa
     1441 ttggatgata aaaactttaa tagtctttta ggttcagtag aaattagtaa taaatctaaa
     1501 aatgaagttt ttataattgg tggtgggggt aaagcaacac caatttatag agcttttact
     1561 aaaaaaggta taggtctgta ttctggaata atacatgaaa atgatattga ttatgaaatt
     1621 ggtagaacta tggggataaa gatgtttaca gaaaatccat ttgagccgat aagtgatgag
     1681 agtttcgatt tggctattag aaatttaaat gattccaaga ttataataga tacaggattt
     1741 agtgtaggag agacaaataa gaggaatata gatattataa aagaggcttt aaaactggat
     1801 aaaaaagttt attcttttag aaatagagat gagagtaaga agtattatga cagtttggat
     1861 agtaagatag aacatataga taaagtttct caaataatca atagtgcaga tataaataat
     1921 ttattataat ttatgaaata aaatgtactt atgtgctata gaaaaaagag tata
//
LOCUS       DACTZW010000188         1973 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.191, whole genome shotgun sequence.
ACCESSION   DACTZW010000188 DACTZW010000000
VERSION     DACTZW010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1973
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.191"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            225..671
                     /locus_tag="JAM15_19200"
     CDS             225..671
                     /locus_tag="JAM15_19200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HAT6800355.1"
                     /translation="MKLIWLIVAVLFGIAEMLTPSLTLIWFSVGAVILIFLSSFIESI
                     FLQILIFAVISIAMLVVATKKIVKKDKGYKSNTNLQAMMSKKGIVTEEISPNNTGLVV
                     VEHETWTAISIDGEKIEKGSTVEVLKIEGVKLVVKKVDATVNVTNQ"
     gene            692..1735
                     /locus_tag="JAM15_19205"
     CDS             692..1735
                     /locus_tag="JAM15_19205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH/Band 7/PHB domain protein"
                     /protein_id="HAT6800356.1"
                     /translation="MGTKIVLSIVLIVVVVAISLTCIRVIKQSKVGIIMRLGKFQKVA
                     ETGVHFLIPFLDKMAYVIDLREIVIDFPPQPVITKDNVTMQIDTVVYYKVTDPVRYVF
                     EIANPIAAIENLTATTLRNIIGELDLDETLTSRDIINVKMRTILDEATDKWGIKVNRV
                     ELKNIMPPQDIQVAMEKQMRAERERREAILQAEGNKSAAILQAEGEKQSAILTAEAKK
                     EAMVRVAEGEKESAILVAEGEAEAIRQTAIAKAQGEAEMIKRTQMATAEGLKLVFSAM
                     KEADIDNNILALKSMEALEKMAEGKSTKLVLPSEAVNFLGTFKGIKEVMSDDNKEIFD
                     IKEALSDNESLKK"
BASE COUNT          808 a          208 c          364 g          593 t
ORIGIN      
        1 ttagtatgca aaattctatg aagcaggaac cctgtgactt tagtcatggg aggttcagac
       61 tactttgtaa caattttaac aaagtatgtt gatataatac tattaaatta atcttagatt
      121 agtttattct attgatttgt agtttaaatt tatattcaaa aacattgtat aaacatataa
      181 tttatatagg gttttataat tcatatgaaa agagggtaga tagtatgaag ttaatatggt
      241 tgatagtagc agtcttattt ggaatagcag aaatgttaac accaagctta acattgatat
      301 ggtttagtgt aggagctgta atacttatat ttttaagtag ctttatagag agtattttct
      361 tacaaatttt aatatttgca gtaatttcta tagcaatgtt agtcgtagct actaaaaaaa
      421 tagtaaaaaa agataaaggc tataaatcta acactaattt acaagcaatg atgtctaaaa
      481 aaggtattgt tacagaagag atttctccaa ataacacagg tctagttgta gttgaacatg
      541 aaacatggac ggctatttct atagatggtg aaaagataga aaaaggttct acagtagaag
      601 tattaaaaat tgaaggggta aaattagttg ttaaaaaagt agacgccaca gttaatgtga
      661 caaaccaata gaataaagga ggatttatag tatgggtact aaaattgttt taagtattgt
      721 attaatagta gtagtcgtag caataagttt aacgtgtata agagttataa aacaatctaa
      781 agtaggtata ataatgagac ttggtaagtt tcaaaaagtg gctgaaacag gtgtacattt
      841 cttaatacca tttttagata aaatggcata tgtaattgac cttagagaaa ttgtaataga
      901 ttttccacct caaccagtta taactaaaga taatgtaact atgcagattg atacagttgt
      961 atattataaa gttacagatc cagttagata tgtgtttgag atagctaatc caatagctgc
     1021 tattgaaaat ttaacagcta caacactaag aaatataatt ggtgaacttg atttagatga
     1081 aacattaaca tcaagagata taataaatgt aaaaatgaga actatccttg atgaagcaac
     1141 agataaatgg ggtataaaag taaatagagt agagttaaaa aatataatgc ctcctcagga
     1201 tattcaagtt gcgatggaaa aacaaatgag agcagaaaga gaaagaagag aggcaatact
     1261 tcaagcagaa ggtaataagt cagctgcaat acttcaagca gaaggtgaaa aacaatctgc
     1321 gatattaaca gcagaagcca aaaaagaagc tatggtacgt gtagcagaag gtgaaaaaga
     1381 atctgctata ttagtggcag aaggtgaagc tgaagctata agacagaccg ctattgctaa
     1441 ggcacaaggt gaggctgaaa tgataaaaag aactcaaatg gcaacagcag aaggtttaaa
     1501 attagttttt tcagcaatga aagaggctga tatagacaat aatattctag cattaaaatc
     1561 tatggaagct cttgaaaaaa tggctgaagg taagtcaaca aaactggttt taccttcaga
     1621 agcagttaat ttcctaggaa cattcaaagg aataaaggaa gttatgagtg atgataataa
     1681 agaaatattt gacataaaag aagctttaag tgataatgaa tcattaaaaa aataaaagag
     1741 ttttgttatc ataggaagga tatggaaatt aaaggtcgaa ttaattaaat atagcacaaa
     1801 aacgcacgtt gaaaagaaga ggacttataa atttttaagt cttcttcttt gtttttatta
     1861 gaaagatgaa attataaaaa taaattaaca gaatctttat acaatttatc ctttactaat
     1921 gtaaaaagtg ttatataata ttatataaaa catatagcaa ataagcatgg ttt
//
LOCUS       DACTZW010000189         1643 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.192, whole genome shotgun sequence.
ACCESSION   DACTZW010000189 DACTZW010000000
VERSION     DACTZW010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1643
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.192"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(230..1078)
                     /locus_tag="JAM15_19210"
     CDS             complement(230..1078)
                     /locus_tag="JAM15_19210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAT6800357.1"
                     /translation="MKNLKIICDSLSDVPKDLLDKYDIDIVSLTVILEEREYKDRIDI
                     SGDEFYKRLREENVYPKTSQATYAQFKEIFEKYTNEDREILYIAGSATATGTYQSAVM
                     AKNDVDGKIYTYDSNLLCMGTGLLVIKAGELASEGKSVDEILPVLDELKEKAFVIFSV
                     DTLEYLQKGGRISSTKAAIGSILNIKPILEIRDGLVSQISQVRGKKNVISKMMELIKS
                     NCGDDLSDQIVYIGYSDDFKEKEQLSKVMQDELRPKEIRFFQIGVCIGAHAGPGVTGI
                     ICLKNK"
     gene            complement(1114..1584)
                     /gene="trmL"
                     /locus_tag="JAM15_19215"
     CDS             complement(1114..1584)
                     /gene="trmL"
                     /locus_tag="JAM15_19215"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HAT6800358.1"
                     /translation="MSLNIVLVEPEIPQNTGNIIRTCAATGSTLHLVKPLGFSLDDKH
                     LKRCGLDYWDIADIQYYDSFEELQEKYPNSKYFFSTTKAKQSHSDVKYEENCFIVFGK
                     ETKGLPEPLLKANMDTCIRVPMLDVEKARSLNLSNSVAIVVYEALRQIGYPNMR"
BASE COUNT          522 a          317 c          164 g          640 t
ORIGIN      
        1 atttataatt tttttatata caatttacaa gtacattttg aaattttttt aataaatctt
       61 actataaaaa agtgtgcaat agattcttat ctatttacac acttccctac aaactaaatc
      121 taatatatca acacttaatt tcatccaaaa taaatccaat ttaacatctc aataattaat
      181 attctatcct aatttaataa aaaaataaat aatggcatcc aaaaatatat tatttatttt
      241 ttaagcatat gataccagtg acaccaggac cagcatgcgc acctatacac acaccaattt
      301 ggaaaaatct aatttcttta ggtcttaatt catcttgcat aaccttagat aattgttctt
      361 tttccttaaa atcatcacta tatcctatat acacaatttg gtctgataaa tcatccccac
      421 aatttgattt tatcaattcc atcatcttag aaattacatt cttctttcct cttacttgag
      481 atatttgcga aactagtcca tctcttattt caagaatcgg ttttatattt aatatacttc
      541 ctattgctgc cttagtagat gatattctac ctcccttttg taaatattcc aatgtatcta
      601 ctgaaaatat aacaaaagcc ttctctttta attcatccaa aacaggtaat atttcatcaa
      661 cagactttcc ttcacttgca agttctcctg cttttattac aagtaaacca gttcccatac
      721 aaagcaagtt agagtcatat gtatatattt taccatccac atcattcttt gccattacag
      781 cactttgata cgtccctgta gctgtggcag accctgctat ataaagtatc tctctatcct
      841 catttgtata tttctcaaaa atttccttaa attgggcata agtagcttga gaagtttttg
      901 gatatacatt ttcttctcta agccttttat aaaattcatc tccagatata tcaattctat
      961 ccttgtattc tctttcctcc agtataactg ttaatgaaac tatatctata tcatatttat
     1021 ctaacaaatc ttttggcacg tctgataaac tgtcacagat tatctttaga tttttcatta
     1081 agtatgctcc tttctcattt aggcttgttg aaactacctc atatttgggt atcctatttg
     1141 tcttaaagcc tcgtacacta caatagcaac tgaatttgat aaatttaatg acctagcttt
     1201 ttcaacatcc aacataggca ctctaataca agtatccata tttgctttca acaaaggttc
     1261 tggtaatccc tttgtttctt tcccaaatac tataaaacaa ttttcttcat atttcacatc
     1321 tgaatgtgac tgtttagcct ttgttgtaga aaaaaagtat ttactatttg gatacttttc
     1381 ttgtaattct tcaaagctat cgtaatattg tatatcagct atatcccaat agtcaagccc
     1441 acatcttttt aggtgtttat catccaatga aaaacccagt ggttttacta aatgtaaagt
     1501 tgaacctgtt gctgcacagg ttcttattat atttcctgta ttttgaggta tttctggttc
     1561 tactaatact atatttaatg acattttaat cctccctaag tatcgctttt atttatcaaa
     1621 ttttatttta taaacagaat aac
//
LOCUS       DACTZW010000190         1628 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.193, whole genome shotgun sequence.
ACCESSION   DACTZW010000190 DACTZW010000000
VERSION     DACTZW010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1628)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1628)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1628
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.193"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            <1..286
                     /locus_tag="JAM15_19220"
     CDS             <1..286
                     /locus_tag="JAM15_19220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAT6800359.1"
                     /translation="NRKLSRLISDVSWSEFIRQLEYKANWHGRKIVKVGKFFASSQIC
                     NKCGYKNEEVKNLNIREWICPSCNETHDRDINASINILKEGLRLITIQNK"
     gene            512..>1628
                     /locus_tag="JAM15_19225"
     CDS             512..>1628
                     /locus_tag="JAM15_19225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HAT6800360.1"
                     /translation="MDIIKKLSHGCTLDCHDCCKFNVYTKENNVVKIEGDKNHPYTKG
                     FICKKGMAHLDRLNHKDRIKTPMLKVDGVWKEISFDKAIEIMAEKLTYYKEKYTSKSV
                     MHYDQYGSGSVLKYIGDIFFNFYGGVSRHKGGPCWSAGMHAQKYDFGVAKSHAIEDML
                     NSKSIFVWGKNPAYTTIHTMQIIKKAKEKGIKIVVIDPIYTKTAQIADKYVQVNPGTD
                     GALAIAMAKIIVEDKLYDEEYINSYVIGFEEYKKYLSSLELSFLIDECGVKENDIREL
                     VDLYTNKYSSINVGYGLQKYKNGGNTIRAIDALGAITGQIGFSGGGVNYANKVYPSVI
                     NSDPYNSQSYGEDREFYVSNISKFIEESLKNTSNKVNY"
BASE COUNT          661 a          151 c          315 g          501 t
ORIGIN      
        1 aaatcgtaaa ctatctcgct taatttctga tgtatcatgg tcagagttta ttcgtcaatt
       61 agaatacaag gctaattggc atggtagaaa aattgtaaaa gtaggtaaat tctttgcaag
      121 ttcacaaata tgcaataaat gtgggtataa aaacgaggaa gttaagaact taaatataag
      181 agaatggatt tgtcctagtt gtaatgaaac tcacgataga gatataaatg caagtataaa
      241 tatattaaaa gaaggattaa gactaataac aattcaaaat aaataactta tgtaagaacc
      301 gtaggaacta cggggatagc ctgtggagaa ttagtaagac atattttagt atgcaaaatt
      361 ctgtgaagca gtaacactgt gactttagtc atgggaggtt cagaaaatat agctatgttt
      421 tatatactgt agttttgaac atagaaagtt taataaatta tagtatatat taatttttaa
      481 taaggtaaga aagtagaaag aaggatattt tatggatata ataaaaaaat taagtcatgg
      541 atgtacatta gattgtcatg attgttgtaa attcaatgtt tatactaaag aaaataatgt
      601 agtaaaaatt gaaggagata aaaatcatcc ttatacaaaa ggttttatat gcaaaaaagg
      661 gatggctcat ttagatagat taaatcataa agatagaata aagactccta tgcttaaagt
      721 tgatggagta tggaaagaga tttcttttga taaggctata gaaataatgg cagaaaagct
      781 tacatactat aaagaaaagt atacatcaaa gtctgtcatg cattatgacc aatatggaag
      841 tgggtctgtg ctaaaataca taggagatat attttttaat ttttatggag gtgttagcag
      901 acataagggt ggtccctgtt ggagtgcagg gatgcatgct caaaaatatg attttggagt
      961 agctaagagt catgctatag aagatatgtt aaatagtaaa agtatatttg tgtggggaaa
     1021 aaatccagca tatactacaa ttcatactat gcaaataatt aaaaaagcta aagaaaaagg
     1081 tataaagata gtagtgattg accccatata tacaaaaaca gctcaaatag cagataagta
     1141 tgtacaagta aatcctggaa cagatggagc tttagctata gctatggcaa aaattatagt
     1201 agaagataaa ttatatgatg aagaatatat aaactcgtat gttattggtt ttgaagaata
     1261 taaaaaatat ttatcttcat tggaattaag ttttttaatt gatgaatgtg gtgttaaaga
     1321 gaatgatata agagagttag tggatttata tactaacaaa tattcaagta taaatgttgg
     1381 atatgggctt caaaaatata aaaatggtgg aaacacaata agagcaatag atgctttagg
     1441 tgctataact ggtcaaatag gatttagtgg tggaggggta aactatgcta ataaagttta
     1501 tccgagtgtt ataaattctg acccttacaa tagccaatca tatggtgaag atagggagtt
     1561 ttatgtaagt aatatcagta aatttataga agaatcttta aaaaatacat caaataaagt
     1621 aaattatg
//
LOCUS       DACTZW010000191         1554 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.194, whole genome shotgun sequence.
ACCESSION   DACTZW010000191 DACTZW010000000
VERSION     DACTZW010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1554)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1554)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1554
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.194"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            11..484
                     /locus_tag="JAM15_19230"
     CDS             11..484
                     /locus_tag="JAM15_19230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAT6800361.1"
                     /translation="MFKEYLIRELKEDDIKNALDLIWNVFEEFESPDYCDEGITTFHQ
                     FIEYNSIIEKIKEKTLFFWGCFDSKKLIGVLAIRNLNHICMLFVDKNYHKHGVAKKLM
                     TTGIQYCICNKFNLTEITVNSSPYAVEVYHKLGFKDIAVEQIVDGIRFTPMKLLI"
     gene            complement(853..1410)
                     /locus_tag="JAM15_19235"
     CDS             complement(853..1410)
                     /locus_tag="JAM15_19235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAT6800362.1"
                     /translation="MRVSREIVIQATSDIVNKDGLNKVSLKVIAEKLGIRTPSLYNHI
                     ESLDDLLLEVAHKGMREMNSQMIKATIGNFGDTAIKCISIAYFNFIISNPGVYETIQW
                     ATWHGNNETLEIFDEYKSLLEKLILSCNLNTKNTGEVLNLIMSVLHGYSTLQLGKSLL
                     SKEEAIKGLADSIDTVLLGIHKKYD"
BASE COUNT          559 a          205 c          169 g          621 t
ORIGIN      
        1 gttgtttata atgttcaaag aatacttaat aagagaatta aaagaagatg atattaaaaa
       61 tgcattagac ttaatctgga atgtatttga agaatttgaa tctccagatt attgtgatga
      121 aggaattacg acatttcatc aatttataga atataattct attattgaaa aaatcaaaga
      181 aaaaacactc ttcttttggg gttgttttga ctctaaaaaa cttattggag tcttagctat
      241 tagaaattta aatcatatat gtatgttatt tgtagataaa aactatcata aacatggtgt
      301 tgcaaaaaaa ttaatgacta caggcataca atactgtatt tgtaataaat ttaatttaac
      361 tgaaataact gtaaattcat caccttatgc tgttgaagtt tatcataaat taggatttaa
      421 agatattgct gttgagcaaa ttgttgacgg tatacgtttt acacctatga aattgttaat
      481 ataataaatt aaataaaaag caaagtctct taaatatttt atagttactt tgcttttaaa
      541 ccaagattta aaataatact atcttttttg ttttttaata atatacttta aaaaccttac
      601 taatatgaac tataatttat tttttgatat cctttttgat taacatataa attaattcaa
      661 ttattaaaca taaactatgt tgtttctctt tatatctctt ctttgtaaac aatattgggc
      721 atttgaaaat aaatattctt aaaatatact gttctcctgt tgattttcct ttggtacaaa
      781 tgataaaatt ttaatttaca tgtcctgtaa agaagtgttt aataaataag ttaaaataat
      841 ttatttacct ccttaatcat attttttatg aatacctaat aacacagtat caatagaatc
      901 ggctaaacct tttatagctt cttctttact caaaagtgat ttcccaagtt gtaaagtcga
      961 ataaccatga agtacactca ttattaagtt taatacttca cctgtattct ttgtatttag
     1021 attacaagaa agaataagtt tttctaataa ggatttatat tcatcaaaga tttctaatgt
     1081 ttcattattt ccatgccaag tagcccactg aattgtttca taaacaccag gattagaaat
     1141 tataaaatta aagtatgcta tacttataca ctttatagct gtatctccaa aatttccaat
     1201 agtcgccttt atcatttgac tattcatctc tctcattcct ttatgagcta cttcaagtaa
     1261 taaatcatct agactttcta tatgattgta caaagatggt gtacgtattc ctagcttttc
     1321 tgcaataact tttaaagaaa ctttgttaag cccatcttta ttaactatat ctgatgtagc
     1381 ttgtataact atttctctac taacacgcat gattttccct ctttcattta aaattaatta
     1441 ctttattagt ttagctaatc taattagttt cgtcaattat tgtaatttat aaaattcttt
     1501 atactcttat aaaatcttga cagtttaatt ataatttaat ataatactaa ttga
//
LOCUS       DACTZW010000192         1251 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.195, whole genome shotgun sequence.
ACCESSION   DACTZW010000192 DACTZW010000000
VERSION     DACTZW010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1251
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.195"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            <1..816
                     /locus_tag="JAM15_19240"
     CDS             <1..816
                     /locus_tag="JAM15_19240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAT6800363.1"
                     /translation="ATNTIAKGVFNIDIPLDSRFNLGEYNYVAIERISEGIYKMKCET
                     AGPIFELGQLIPIEYIDKLETAELTEILINGEDEESEDSLRQRYYDSLNSQSFGGNIQ
                     NYKDEVNKLPDVGGVKVYPVWNGGGTVKLVIINSNFKVPSEELVNLVQEEIDPIGHQG
                     EGLGLAPIGHRVTVEGVASTTINISAEITYKSGYTWENIKIIAEEAINDYLNELNMSW
                     EDEENLIVRISQIETRLLSIDGVLDIANTMINDVKSNLTIDSNSIVVRGEVVG"
     gene            809..>1251
                     /locus_tag="JAM15_19245"
     CDS             809..>1251
                     /locus_tag="JAM15_19245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmfQ family protein"
                     /protein_id="HAT6800364.1"
                     /translation="MDKEINLINYLPQILQDKEEYIKVFNVENKEIKTLHDKLKDLSN
                     DQFLEDLTISGIKRWEKIMSITPKSNESLEDRRFRIFSKYISKLPYSERFLRNWLDNV
                     VGEGNYELTINNANYNIHLESDARNQDWFEEVHSFVSNIKPCNMTL"
BASE COUNT          513 a          135 c          248 g          355 t
ORIGIN      
        1 gcaaccaata caattgcaaa aggagttttt aacatagata ttccacttga ttctaggttt
       61 aatctaggag aatataacta tgtagcaatt gagagaatat ctgaaggtat atataagatg
      121 aaatgtgaga ctgctggacc tatttttgag ttggggcaac taattcctat cgaatatata
      181 gacaaattag aaacagcaga actgacagaa atactgataa atggagaaga tgaagaaagt
      241 gaagatagtt tgagacaaag atattatgat agtttaaatt cccaatcttt tgggggtaat
      301 atacaaaact ataaggatga agttaataaa ttgcctgacg ttggaggagt taaagtttat
      361 cctgtttgga acggcggagg aactgttaag ttagtaataa ttaactctaa ttttaaagtg
      421 ccaagtgaag aattagtaaa cttagttcaa gaagaaattg acccaattgg acaccaagga
      481 gaaggcttag gattagcacc gattggacac cgagtaactg ttgaaggagt tgcaagtaca
      541 actataaata tatcagcaga aataacatat aagagtggat atacatggga gaatataaaa
      601 ataattgcag aagaagcaat aaacgactat ttaaatgagt taaatatgag ttgggaagat
      661 gaagaaaact taatagtccg tatatctcaa attgaaacta gattacttag tattgatgga
      721 gtattagaca ttgcaaacac aatgataaat gatgttaaat ctaatctaac aatagatagt
      781 aacagcatag tagtgagagg tgaggtagtt ggataaagag attaatctaa taaattactt
      841 gccacaaatt ctacaagata aagaagaata tataaaagta tttaatgtag aaaataaaga
      901 aataaaaaca ctacatgata aattaaagga cctatcaaat gaccagtttt tagaggacct
      961 aactataagt ggtataaaaa gatgggaaaa gataatgtct ataactccta aaagtaatga
     1021 gagtttagaa gatagaaggt ttaggatttt tagtaaatat ataagtaaat taccttactc
     1081 agagagattt ttaaggaact ggctagataa tgtagttgga gaaggcaatt atgaattaac
     1141 tattaataat gctaattata acatacacct tgagagtgat gctagaaatc aagattggtt
     1201 tgaggaagtt cattcttttg taagtaatat taagccatgt aacatgacac t
//
LOCUS       DACTZW010000193         1248 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.196, whole genome shotgun sequence.
ACCESSION   DACTZW010000193 DACTZW010000000
VERSION     DACTZW010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1248)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1248)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1248
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.196"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            <1..813
                     /locus_tag="JAM15_19250"
     CDS             <1..813
                     /locus_tag="JAM15_19250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HAT6800365.1"
                     /translation="ATHTIAKGVFNIDIPLDSRFNLGEYNYIATERISEGIYKMKCET
                     TGPIFELGQLIPIEYVDKLETAELTEILINGEDEESEDSLRQRYYNSLNSQSFGGNIQ
                     NYKDEVNKIQDVGGVKVYPVWNGGGTVKLVIINSNFKVPSSDLVNLVQEEIDPNSKGE
                     GLGLAPIGHRVTVEGVTSTTINISAEITYKSGYTWENIKTIAEEAIDDYLNELNMSWE
                     DEENLIVRISQIETRLLSIDGVLDIANTMINDVKSNLTIDSNSIVTRGEVVG"
     gene            806..>1248
                     /locus_tag="JAM15_19255"
     CDS             806..>1248
                     /locus_tag="JAM15_19255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmfQ family protein"
                     /protein_id="HAT6800366.1"
                     /translation="MDKEINLINYLPQILQDKEEYIKVFNVENKEIKTLYDKLKDLSN
                     DQFLEDLTISGIKRWEKIMSITPKSNESLEDRRFRIFSKYISKLPYSERFLRNWLDNV
                     VGEGNYELTINNATYNIHLESDARNQDWFEEVHSFVSNIKPCNMTL"
BASE COUNT          509 a          142 c          240 g          357 t
ORIGIN      
        1 gccactcata cgattgctaa aggtgttttc aatatagata ttcctcttga ttcaagattc
       61 aacctaggag aatacaatta tattgcaact gaaaggatta gcgaaggtat atataaaatg
      121 aaatgcgaaa ctactggacc tatttttgaa cttggtcagt tgattccaat tgaatatgta
      181 gacaaattag aaacagcaga actgacagaa atattgataa atggagaaga tgaagaatct
      241 gaggacagtt taagacaaag atattataat agtttaaatt ctcagtcatt tggtggaaat
      301 atacaaaact ataaggatga agttaacaag atacaggatg ttggaggagt taaggtttat
      361 cctgtttgga atggtggagg gactgttaaa ttagtaataa ttaactctaa ttttaaagta
      421 ccatctagtg atttagttaa cctagtacaa gaagaaattg acccaaactc aaaaggtgaa
      481 ggcttaggat tagcaccaat aggtcataga gtcacagttg aaggagtaac aagtacaact
      541 ataaacatat cagcagagat aacatataaa agtggctaca cttgggagaa tataaagact
      601 atagcagagg aagcaattga cgactactta aatgaactta acatgagctg ggaagatgaa
      661 gaaaacttaa tagttcgtat atctcaaatt gaaactagat tgcttagtat agatggagta
      721 ttagatattg caaatactat gataaatgat gtcaaatcta atctaacaat agatagtaat
      781 agcatagtaa cgagaggtga ggtagttgga taaagagatt aatctaataa attacttacc
      841 acaaattcta caagataaag aagaatatat aaaagtattt aatgtagaaa ataaagaaat
      901 aaaaacatta tatgataaat taaaggacct atcaaatgac cagtttttag aggacctaac
      961 tataagtggt ataaaaagat gggaaaagat aatgtctata actcctaaaa gtaatgagag
     1021 tttagaagat agaaggttta ggatttttag taaatatata agtaaactac cttactcaga
     1081 gagattttta aggaactggc tagataatgt agttggagaa ggcaattatg aattaactat
     1141 taataatgct acttataaca tacaccttga gagtgatgct agaaatcaag attggtttga
     1201 ggaagttcat tcttttgtaa gtaatattaa gccatgtaac atgacact
//
LOCUS       DACTZW010000194         1162 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.197, whole genome shotgun sequence.
ACCESSION   DACTZW010000194 DACTZW010000000
VERSION     DACTZW010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1162
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.197"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            171..314
                     /locus_tag="JAM15_19260"
     CDS             171..314
                     /locus_tag="JAM15_19260"
                     /inference="COORDINATES: protein motif:HMM:NF014609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800367.1"
                     /translation="MNKKFRLYQVDSFTKERFTGNPAGVITNADGLSESQMQKITREL
                     NNS"
     gene            336..1085
                     /locus_tag="JAM15_19265"
     CDS             336..1085
                     /locus_tag="JAM15_19265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis isomerase"
                     /protein_id="HAT6800368.1"
                     /translation="MAKNHQENYDVHIRFFTPTNEVPICGHATIAAHYVRAVENQFNN
                     KTVFQKTGAGILPVDIIKKDNDYEIIMTQGKIEVSPPLQQTYQKRLLNAFGILNEDIR
                     TDCPIAISSTGHSKVMIGIKELSTLNSLSPNLYELSKISQEIKCNGYYIFTLHNKETL
                     QVHGRMFAPAIGISEDPVTGNANGPLGAYLVHYKVIPTPNTEFIFEAVQGEAIKRKGK
                     MLVKVIILDNKPVEVKIIGKAVIAFSTNIEI"
BASE COUNT          475 a          152 c          152 g          383 t
ORIGIN      
        1 gtagcataga gccttacata atactacttt tttagatgta tatttttaaa ttttaatata
       61 gacatatgtt attttattaa ttttatttaa acagataata ataaataata atttatctca
      121 agttttctat gtagataaac taatctaatg tttagaaagg attatataat atgaataaaa
      181 aatttcgtct ttatcaagtt gactcattta caaaagaaag attcacaggt aatccagctg
      241 gtgtaattac aaatgctgat ggcttatctg aatcacaaat gcaaaaaata acaagagaat
      301 taaataattc ataaactgct tttattttca ataaattggc taaaaatcat caagaaaatt
      361 atgatgtaca tatcagattt tttacaccaa ctaatgaagt tcctatatgt ggtcatgcta
      421 ctattgctgc ccattatgtt agagcagtag aaaaccaatt caataacaaa acagtatttc
      481 aaaaaactgg tgctggaata ttaccagttg atattataaa aaaagataat gattatgaaa
      541 taattatgac acaaggaaaa attgaagtat ctccaccatt acaacaaacc tatcaaaaaa
      601 gattacttaa tgcatttggt attttaaatg aagatattcg tacagattgt cctattgcca
      661 tatcatctac aggacattca aaagttatga ttggaataaa ggaattatca acattaaata
      721 gtttatctcc aaatttatat gaattatcga aaataagtca agaaataaaa tgtaatggat
      781 attatatttt tacattacat aataaagaaa ctctacaagt tcatggaaga atgtttgctc
      841 ctgcaattgg tatttcagaa gaccctgtta caggaaatgc taatggaccc ttaggtgcgt
      901 accttgtaca ttataaagta atacctacac ccaacacaga gtttatattt gaagcagttc
      961 aaggagaagc aataaaacgc aaaggcaaga tgttagtaaa agtaattatt ttagataata
     1021 agccagttga agtaaaaata attggaaaag ctgtaattgc attctcaaca aacatagaaa
     1081 tctaattata gattccttct aagtaaattt ttgaactttt taatactaat ttaataacaa
     1141 actaatttat atacaatcaa at
//
LOCUS       DACTZW010000195         1142 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.198, whole genome shotgun sequence.
ACCESSION   DACTZW010000195 DACTZW010000000
VERSION     DACTZW010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1142)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1142)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1142
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.198"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            21..890
                     /locus_tag="JAM15_19270"
     CDS             21..890
                     /locus_tag="JAM15_19270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HAT6800369.1"
                     /translation="MEYDMPLYRPPSEAYSLIIQVTLGCSHNKCTFCSMYKSKKFKIK
                     PLEVIKNEIDIFRRYYKHVERIFLADGDALIIPMEKLRDIILYIKEVFPECERITMYG
                     SPKSIEKKSDDELKELRKLGVKMIYLGLESGSNEVLEDIKKGFSSEQLIKVGRKVKKS
                     GIKLSATVIAGLGGTKKTHQHAVDTGKMLGAISPDYVGVLSLMVEPNTELYDLLKAGE
                     FTILEDKAVLQEIKEMIKNIDANEKIVFRSNHASNYANLKGVLPDDKQRLIDEIDYYL
                     SNQKLKREEYRRL"
BASE COUNT          483 a          111 c          194 g          354 t
ORIGIN      
        1 attacaaggg ggattttaat atggaatacg atatgccact ttacagacca ccaagtgagg
       61 cttatagtct tataatacaa gtcacactag gatgttctca taacaaatgt acgttttgta
      121 gtatgtacaa atctaaaaaa tttaaaataa agccactaga agtaataaaa aatgaaattg
      181 atatatttag aagatattat aagcatgtag aaagaatatt cttagcagat ggagatgcat
      241 tgataatacc aatggagaaa ttaagagata ttattttata tataaaagaa gtttttccag
      301 agtgtgaaag aattactatg tacggctctc ctaaatctat agagaaaaaa tctgatgatg
      361 aacttaaaga attaagaaaa cttggtgtta aaatgattta tctagggctt gaaagtggaa
      421 gcaatgaagt attagaagat attaagaaag gttttagtag tgaacaatta ataaaagttg
      481 gtagaaaagt taaaaaaagt gggattaaat tatcagccac tgtaatagca ggtcttggag
      541 gaactaaaaa aacacatcag catgcagttg atacaggaaa aatgttagga gcaatttcac
      601 cagattatgt gggtgtactt agtttaatgg tagaacctaa tactgaactt tacgatttac
      661 ttaaggcagg agagtttaca atactagagg ataaggctgt gttacaagaa attaaagaga
      721 tgataaagaa tatagatgct aatgaaaaaa ttgtatttag aagtaatcat gcatcaaatt
      781 atgctaattt aaaaggtgta ttacctgatg ataaacaacg tctaattgat gaaattgatt
      841 actatctaag taaccaaaag ctaaaaagag aagaatatag aagactatag tttttgatat
      901 atcaatctat attgataggt aaatactaag attatttaga tacaaaaaat catgctacat
      961 taatagttgc ttactattga tgtagcatga tttttttatt aaaaaacaaa atggtatatt
     1021 catataataa tatatcaata ataatgaaaa tgtgaactag tttaatagaa ttttacctat
     1081 tataataaaa acaggaattt aaataataaa aagtaaagta actttttatt aagtaacttt
     1141 at
//
LOCUS       DACTZW010000196         1115 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.199, whole genome shotgun sequence.
ACCESSION   DACTZW010000196 DACTZW010000000
VERSION     DACTZW010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1115)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1115)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1115
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.199"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            154..603
                     /locus_tag="JAM15_19275"
     CDS             154..603
                     /locus_tag="JAM15_19275"
                     /inference="COORDINATES: protein motif:HMM:NF021182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800370.1"
                     /translation="MSLIEYRGYDFENKKWIYSKTIMWSNLVDCLLMLKEDFKWRKVC
                     DVGICSEEWDRNNQEIYEGDILKEYYNPRDTSQYGVVKRDVGSIKIYLEWHYLKKFEG
                     EWIEIVNKTEIYHSRDYKVVGNEYENLEEVRKEFLERKEKLENECLS"
     gene            724..999
                     /locus_tag="JAM15_19280"
     CDS             724..999
                     /locus_tag="JAM15_19280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800371.1"
                     /translation="MKYEEYEDLKNRVESYEDLQGSAEFAERVIENLEDVDCPIRIGF
                     KFPNKEDYQKIDLDIAAKDSNSIFIRTELAKAFKEILSKYEMDMENI"
BASE COUNT          455 a           73 c          249 g          338 t
ORIGIN      
        1 tatattcaag aggtgacaga tggtattagc aaatgtggag caagtaatta agttagctga
       61 aaagatatta aataagaaaa agtgttctgt taataaagct attgatatag ctataaaaat
      121 attaagtaaa tatgagtgcg aggggatgat taaatgagtt tgattgaata tagaggctat
      181 gattttgaaa ataaaaagtg gatttattct aaaacgataa tgtggagtaa tcttgtagac
      241 tgtttattaa tgctgaaaga agattttaaa tggcgaaaag tttgtgatgt tggaatatgt
      301 tctgaggaat gggatagaaa taatcaagaa atctatgaag gggatatatt gaaagaatat
      361 tataatcctc gtgatacaag ccaatatgga gttgtaaaaa gggatgttgg tagtattaaa
      421 atatatttgg aatggcatta tctaaagaag tttgaaggag aatggataga gattgtaaat
      481 aaaacagaaa tatatcatag cagagattac aaagtggtag gaaatgaata cgagaattta
      541 gaggaagtta gaaaagagtt cttagaacgt aaggagaaac ttgaaaatga atgtcttagc
      601 tagtgcgata ttagtaatag gaagttttat agcgggtagg atttatgagt atagattgaa
      661 tctaaaagag tgtgaaaatt gcgataaaaa agaattttaa taaattatag gaggtactag
      721 gttatgaaat atgaagaata tgaagattta aaaaatagag tagaaagtta tgaggattta
      781 caaggtagtg cagagtttgc agagcgagtt atagaaaatc ttgaggatgt agattgtcct
      841 ataagaatag gatttaagtt tcctaacaaa gaggattatc aaaagataga ccttgatata
      901 gctgctaaag attcaaattc aatttttata agaacagagt tagcaaaagc atttaaagag
      961 attttatcta aatatgaaat ggatatggaa aatatctaat taaaacagtt tagagagttg
     1021 caaaatgtct tttaattaaa ttattgttga agtattttgt ggctctcaaa aatgaaaata
     1081 aggggtgaac aaatgtcaaa gtatgtgctt agatg
//
LOCUS       DACTZW010000197         1038 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.200, whole genome shotgun sequence.
ACCESSION   DACTZW010000197 DACTZW010000000
VERSION     DACTZW010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1038
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.200"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(2..73)
                     /locus_tag="JAM15_19285"
     tRNA            complement(2..73)
                     /locus_tag="JAM15_19285"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(39..41),aa:Asn,seq:gtt)
     gene            complement(80..153)
                     /locus_tag="JAM15_19290"
     tRNA            complement(80..153)
                     /locus_tag="JAM15_19290"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(119..121),aa:Cys,seq:gca)
     gene            complement(161..236)
                     /locus_tag="JAM15_19295"
     tRNA            complement(161..236)
                     /locus_tag="JAM15_19295"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(201..203),aa:Lys,seq:ttt)
     gene            complement(245..321)
                     /locus_tag="JAM15_19300"
     tRNA            complement(245..321)
                     /locus_tag="JAM15_19300"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(285..287),aa:His,seq:gtg)
     gene            complement(329..405)
                     /locus_tag="JAM15_19305"
     tRNA            complement(329..405)
                     /locus_tag="JAM15_19305"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(369..371),aa:Pro,seq:tgg)
     gene            complement(429..505)
                     /locus_tag="JAM15_19310"
     tRNA            complement(429..505)
                     /locus_tag="JAM15_19310"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(469..471),aa:Ile,seq:cat)
     gene            complement(520..593)
                     /locus_tag="JAM15_19315"
     tRNA            complement(520..593)
                     /locus_tag="JAM15_19315"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(557..559),aa:Met,seq:cat)
     gene            complement(600..675)
                     /locus_tag="JAM15_19320"
     tRNA            complement(600..675)
                     /locus_tag="JAM15_19320"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(640..642),aa:Phe,seq:gaa)
     gene            complement(679..767)
                     /locus_tag="JAM15_19325"
     tRNA            complement(679..767)
                     /locus_tag="JAM15_19325"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(731..733),aa:Ser,seq:tga)
     gene            complement(856..931)
                     /locus_tag="JAM15_19330"
     tRNA            complement(856..931)
                     /locus_tag="JAM15_19330"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(896..898),aa:Gln,seq:ttg)
     gene            complement(939..1015)
                     /locus_tag="JAM15_19335"
     tRNA            complement(939..1015)
                     /locus_tag="JAM15_19335"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(979..981),aa:Arg,seq:tct)
BASE COUNT          279 a          278 c          233 g          248 t
ORIGIN      
        1 gctccaaggg tggggctcga acccacagcc taccggttaa cagccggttg ctccaccgtt
       61 gagctacctt ggaatatttt ggaggcgaca cccagattcg aactggggat caaggagttg
      121 cagtccactg ccttaccact tggctatgtc gccacctttt tggtgatcta tccgcgactc
      181 gaacgcggga caccctgatt aaaagtcagg tgctctaccg actgagctaa tagaccatat
      241 gaattggggt ggataatgag agtcgaactc acgacctcca gagccacaat ctggcgctct
      301 aaccaactga gctataccca ccttatattg gtcgaggtga agggactcga acccccggcc
      361 ccatggtccc aaaccatgtg cgctaccaaa ctgcgctaca cctcgaattt atattaatta
      421 atttaatgtg gtgggccatc agggactcga accccagacc taccggttat gagccgggcg
      481 ctctaaccaa ctgagctaat ggcccacatt aaattttagt agcggtaata ggagtcgaac
      541 ctatgacctt tcgggtatga accgaacgct ctagccaact aagctatacc gccatatttt
      601 ggtgcccaga ggcggaatcg aaccaccgac acggggattt tcagtcccct gctctaccga
      661 ctgagctatc tgggcatttg gcggagaggg tgggattcga acccacggcc cctttcgaag
      721 tcactggttt tcaagaccag ctccttaaac cactcggaca cctctccaca ttcggatact
      781 taaacttatt ctaaaattga acctaactat atttaaaata aaaataattc aaatatagct
      841 tagtaataca tcatttggct ggggatgcag gactcgaacc tacgcataca tgagtcaaag
      901 tcatgtgcct taccgacttg gctaatcccc aatatatgtg gtgagcgcac agggattcga
      961 accccggaca cacgccttag aagggcgttg ctctatccag ctgagctatg cacccacaat
     1021 ttatatatgt atatcaaa
//
LOCUS       DACTZW010000198          933 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.201, whole genome shotgun sequence.
ACCESSION   DACTZW010000198 DACTZW010000000
VERSION     DACTZW010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 933)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 933)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..933
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.201"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(89..418)
                     /locus_tag="JAM15_19340"
     CDS             complement(89..418)
                     /locus_tag="JAM15_19340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800372.1"
                     /translation="MKIFLLTILLIIICILANYVKNRIYKKSINNLKYKYSVGEKIIY
                     HQINCYYNRMVGCEILEKCYSTKFRKRNTPLYKVKAYVGDNNTTWVIPEWRIECLATT
                     YGEFPKY"
     gene            complement(500..>933)
                     /locus_tag="JAM15_19345"
     CDS             complement(500..>933)
                     /locus_tag="JAM15_19345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HAT6800373.1"
                     /translation="NATKVKDDKYKTKMFKNTAENWITNALGNDIKQAEDVRSILNYT
                     LKEKHEVDINEFADKSIKDDELKDSFKEHMEEKGLDEGFSIDKKWVDKKLKKRNIKTD
                     NGFEIKGNLTDFEDPMKYTVRQNQNGSIDIIIKNVTFYEEK"
BASE COUNT          277 a          171 c           75 g          410 t
ORIGIN      
        1 ttttttataa gtcaaagtaa gtctataaca ttctagtttc attcacaaac ttgccttgac
       61 tatttatact ccaaccaatt tttattattt aatatttagg aaattctcca taagtcgtag
      121 caagacattc aattctccac tctggtataa cccacgttgt attgttatca cctacatatg
      181 cttttacttt ataaagcggg gtatttcttt ttctaaattt cgtactataa catttttcta
      241 aaatttcaca accaaccatt ctgttatagt aacagtttat ttgatgatat ataatctttt
      301 cccctacaga atatttatat tttaaattat ttatagattt tttatatatg cgatttttta
      361 cataatttgc taatatacaa ataattatta gcagtatagt caataaaaaa atcttcataa
      421 gttattcctc ctaactagtt taaatttaca tcctcttatt atttacttct ccttctctag
      481 ccaatagtca catgagtacc tacttttcct cataaaatgt tacattctta ataattatat
      541 ctatagaccc attttgattt tgtcttactg tatatttcat tgggtcctca aaatcagtta
      601 agttaccttt tatttcaaag ccattgtcag tttttatatt tctcttttta agctttttat
      661 caacccattt tttatctata ctaaatcctt catcaagacc tttttcttcc atatgttctt
      721 taaaactatc ttttaactca tcatctttaa tcgatttatc agcaaactca tttatatcaa
      781 cctcatgttt ttctttcaaa gtataattta atatacttct tacatcctct gcttgtttta
      841 tatcatttcc aagagcatta gttatccaat tttcggctgt atttttaaac atcttagtct
      901 tatacttgtc atctttcact ttagtagcat tta
//
LOCUS       DACTZW010000199          765 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.202, whole genome shotgun sequence.
ACCESSION   DACTZW010000199 DACTZW010000000
VERSION     DACTZW010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..765
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.202"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            <1..615
                     /locus_tag="JAM15_19350"
     CDS             <1..615
                     /locus_tag="JAM15_19350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase"
                     /protein_id="HAT6800374.1"
                     /translation="GDKVKIILPGTAYDNKVYTVKDNGGRIYVETNGTYHIDILLANA
                     SECKKFGRKNGYIIIGGDEEQTYQVEGNNQSSTNNNSKEDKLISIAKSKLGCNYVYGA
                     EGPNTFDCSGFTQWCYKQIGIKIPRTVATQSKAGSAVDLKDRSKWKAGDLLCRVGGGS
                     SNHVMMYIGNGQMIHSPQTGDVVKIESVNSYRKGKAYTHVRRFI"
     gene            629..>765
                     /locus_tag="JAM15_19355"
     CDS             629..>765
                     /locus_tag="JAM15_19355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 domain-containing protein"
                     /protein_id="HAT6800375.1"
                     /translation="MSQELLQIIKKAAMDAVETSNPMTLAFGTIESVNPLVVKIEQKA
                     S"
BASE COUNT          314 a           81 c          163 g          207 t
ORIGIN      
        1 ggagataaag taaaaattat acttcctggt actgcctatg acaacaaagt atatacagtt
       61 aaagataatg gaggaagaat atatgttgaa acaaacggaa catatcatat agatatacta
      121 ttagctaatg ctagtgaatg taaaaaattt ggtagaaaga atggctatat aattataggt
      181 ggagatgaag aacaaacata tcaagttgaa ggtaataacc aaagtagtac aaataataac
      241 tctaaagaag ataaattaat tagtatagca aaaagtaaac tgggttgtaa ttatgtgtat
      301 ggagcagaag gtcctaatac ttttgattgt tctggattca ctcaatggtg ttataaacaa
      361 ataggtataa aaattcctag gactgttgca acgcaaagta aggcaggcag tgcagtagat
      421 ttaaaagata gaagcaagtg gaaagcagga gacttattat gtagagttgg tggaggtagt
      481 agtaatcacg taatgatgta tattggaaat ggtcaaatga ttcattcacc acaaacagga
      541 gatgtggtaa aaatagagtc agttaattca tatagaaaag gaaaagcata tacacatgtg
      601 agaagattta tataagtgag gtgataaagt gtcacaagaa ttattgcaaa taattaagaa
      661 ggctgcaatg gatgcagtag aaacaagtaa tccaatgact cttgcatttg gaactataga
      721 aagtgttaat cctttagtag ttaagataga gcaaaaagca tcctt
//
LOCUS       DACTZW010000200          758 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.203, whole genome shotgun sequence.
ACCESSION   DACTZW010000200 DACTZW010000000
VERSION     DACTZW010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..758
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.203"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            70..>758
                     /locus_tag="JAM15_19360"
     CDS             70..>758
                     /locus_tag="JAM15_19360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAT6800376.1"
                     /translation="MEKKYFEIHGVPSILWGNPSSKLYIYIHGQCGNKEEAEAFANIA
                     VPHEYQVLSVDLPEHGERKREKNSFNPWHVVPELVSIMEYAKCHWNQISLYANSIGAW
                     FSMLSFEKENLRECIFVSPILDMQQLISNMMLWANVSEEQLKHELIIPTSFGHTLSWE
                     YLQYVKQHPITQWNVPTKILYGKHDELTEIGVVEKFVEKFNCNLTIIENGKHWFNTPQ
                     ELNSLYEWLNT"
BASE COUNT          282 a          107 c          125 g          244 t
ORIGIN      
        1 attacaacat tattttatag tttgattaat tcaacaatca ctaatatatc aaactgaaag
       61 gagattttta tggaaaaaaa atatttcgaa attcatggag ttccttcaat cctttgggga
      121 aatccttcaa gtaaattata tatttacata catggacaat gtggcaataa agaggaggct
      181 gaagcttttg ctaatattgc agttccacat gagtatcaag ttttaagtgt tgatttgcct
      241 gaacatggag aacgtaaaag agaaaaaaat tcatttaacc catggcatgt tgttccagaa
      301 ttagtatcta ttatggaata tgcaaagtgc cactggaatc aaatttcgtt atatgcaaat
      361 agcattggag catggtttag tatgttaagc tttgaaaaag agaacttaag agagtgtatt
      421 tttgtatctc caattctaga tatgcaacag ctcatttcaa atatgatgct ttgggcaaat
      481 gtatcagaag aacagcttaa acatgaacta attatcccaa cttcatttgg gcatactctt
      541 tcatgggaat atctacaata tgtaaaacaa catcctatca ctcaatggaa tgtaccaaca
      601 aaaatattat atggtaaaca tgatgaactt actgaaatcg gtgttgtaga gaaatttgta
      661 gaaaagttta attgcaacct tactattata gaaaatggca aacattggtt taacacacca
      721 caagaattaa attcattata tgaatggtta aatacttt
//
LOCUS       DACTZW010000201          738 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.204, whole genome shotgun sequence.
ACCESSION   DACTZW010000201 DACTZW010000000
VERSION     DACTZW010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..738
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.204"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            <1..102
                     /locus_tag="JAM15_19365"
     CDS             <1..102
                     /locus_tag="JAM15_19365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 domain-containing protein"
                     /protein_id="HAT6800377.1"
                     /translation="TDTFKRYTDKKIGDKLVLIRMQGGQQYLILDRM"
     gene            107..526
                     /locus_tag="JAM15_19370"
     CDS             107..526
                     /locus_tag="JAM15_19370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HAT6800378.1"
                     /translation="MIPSDNVDYDIEDVSIINFNVRQEPSKTFKLNMERNKVDGICDD
                     VEALKQTIFLTLNTERYQHLIYSWNYGVELNDLIGEPISYVIPELERRIKEALIQDDR
                     IENVDNFQFENIKGKVHCKFTVYSKYGNIKAEKVVSV"
     gene            539..>738
                     /locus_tag="JAM15_19375"
     CDS             539..>738
                     /locus_tag="JAM15_19375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAT6800379.1"
                     /translation="MTFENIIKRMLDSVPDTFDKREGSIIYNALAPVAIELTETYIAM
                     DELLDQTFVDTASYYYLEKRCK"
BASE COUNT          302 a           69 c          141 g          226 t
ORIGIN      
        1 acagatacat ttaaaagata tacagataaa aagataggag ataaattagt tttaattcgt
       61 atgcaaggag ggcaacaata tttaatatta gataggatgt gatgaagtga taccaagcga
      121 taatgttgac tatgatattg aagatgtatc aattataaat tttaatgtaa gacaagaacc
      181 aagtaaaaca tttaaactga atatggagag aaataaagta gatggtattt gtgatgatgt
      241 tgaggcatta aaacagacca tctttttaac tttaaatact gaaaggtatc aacatttaat
      301 atatagctgg aattatggag tagaattaaa tgatttaatt ggagagccta tttcttatgt
      361 aatacctgaa cttgaaagac gaatcaaaga agcactaatt caagatgata ggattgaaaa
      421 tgtagataat tttcagtttg agaatataaa gggaaaagta cattgtaaat tcacagtcta
      481 cagtaaatat ggaaatataa aagcagagaa ggtggtgagt gtataattgt ttgagttaat
      541 gacatttgaa aatataatta aaagaatgtt agatagtgta ccagatactt ttgataaaag
      601 ggaaggttct ataatatata atgctcttgc tcctgttgct atagaactta cagaaacata
      661 cattgcaatg gatgaattac tagaccaaac attcgtagat actgctagtt attactattt
      721 agagaagaga tgtaaaga
//
LOCUS       DACTZW010000202          728 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.205, whole genome shotgun sequence.
ACCESSION   DACTZW010000202 DACTZW010000000
VERSION     DACTZW010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 728)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 728)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..728
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.205"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            <1..>728
                     /locus_tag="JAM15_19380"
     rRNA            <1..>728
                     /locus_tag="JAM15_19380"
                     /product="16S ribosomal RNA"
BASE COUNT          195 a          157 c          236 g          140 t
ORIGIN      
        1 caggatggac ccgcgtctga ttagctagtt ggtaaggtaa cggcttacca aggcgacgat
       61 cagtagccga cctgagaggg tgatcggcca cattggaact gagacacggt ccaaactcct
      121 acgggaggca gcagtgggga atattgcaca atgggcgaaa gcctgatgca gcaacgccgc
      181 gtgagtgatg aaggccttcg ggtcgtaaaa ctctgtcctc aaggaagata atgacggtac
      241 ttgaggagga agccccggct aactacgtgc cagcagccgc ggtaatacgt agggggctag
      301 cgttatccgg atttactggg cgtaaagggt gcgtaggcgg tctttcaagt caggagtgaa
      361 aggctacggc tcaaccgtag taagctcttg aaactgggag acttgagtgc aggagaggag
      421 agtggaattc ctagtgtagc ggtgaaatgc gtagatatta ggaggaacac cagttgcgaa
      481 ggcggctctc tggactgtaa ctgacgctga ggcacgaaag cgtggggagc aaacaggatt
      541 agataccctg gtagtccacg ctgtaaacga tgagtactag gtgtcggggg ttaccccctt
      601 cggtgccgca gctaacgcat taagtactcc gcctgggaag tacgctcgca agagtgaaac
      661 tcaaaggaat tgacggggac ccgcacaagt agcggagcat gtggtttaat tcgaagcaac
      721 gcgaagaa
//
LOCUS       DACTZW010000203          628 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.206, whole genome shotgun sequence.
ACCESSION   DACTZW010000203 DACTZW010000000
VERSION     DACTZW010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 628)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 628)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..628
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.206"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            <1..>628
                     /locus_tag="JAM15_19385"
     CDS             <1..>628
                     /locus_tag="JAM15_19385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAT6800380.1"
                     /translation="NYENDISGIENQVIGMYSKGMSTRDISSHLKSIYGIDMSHSLIA
                     KITDRVLPLAHEWQNRPLDMVYPIVFMDAIHYKVRSEGRIINKAAYIAIGVNLEGIKE
                     VLGIWIGENESSKYWLKVLTDVKNRGVKDILIASVDGLVGFSDAIKAVFPDTEIQRCV
                     VHQIRNTLNYVSYKNRKEFAKDLKKVYAAITEEVALSELSLLEEKWCNQ"
BASE COUNT          243 a           70 c          125 g          190 t
ORIGIN      
        1 aattatgaaa atgatatatc aggaatagag aaccaagtga ttggaatgta ctcaaaaggt
       61 atgtctactc gagatatatc aagccacctt aagagtattt acggaattga tatgtctcat
      121 tctctaatag ctaaaattac tgatagagtt ctacctttag ctcatgaatg gcaaaacaga
      181 cctcttgata tggtttatcc aattgtattt atggatgcta tacattataa agttagaagt
      241 gaaggtagaa taataaacaa agctgcatat atagccatag gtgttaactt agaaggtata
      301 aaggaggtct taggaatatg gattggagaa aatgaaagtt caaagtattg gctaaaggtg
      361 cttacagatg tcaaaaacag aggagttaag gatatattaa tagcttctgt agatggatta
      421 gttggatttt ctgatgcaat taaagcagta tttcctgata ctgaaataca aagatgtgtt
      481 gtacatcaaa ttagaaatac tttaaattat gtatcatata aaaatagaaa agaatttgca
      541 aaagatttaa agaaagtata tgctgcaatt acagaggaag tagcattaag tgagctatcg
      601 ctcttagagg aaaaatggtg taatcaat
//
LOCUS       DACTZW010000204          534 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.207, whole genome shotgun sequence.
ACCESSION   DACTZW010000204 DACTZW010000000
VERSION     DACTZW010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..534
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.207"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(133..333)
                     /locus_tag="JAM15_19390"
     CDS             complement(133..333)
                     /locus_tag="JAM15_19390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011723062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAT6800381.1"
                     /translation="MKNGIVKWFNNEKGFGFISVEGEDDVFVHFSAIQNDGYKTLEEG
                     EKVSFDITQGNRGPQAENVNRI"
BASE COUNT          213 a           73 c           49 g          199 t
ORIGIN      
        1 aaaaagttag tttaagtttg acgcttttct aaagtaactt cttatttttg taattaaaaa
       61 taaatataat aaacaacaaa aaagagccct cgatagctcc ttttctaaaa tatatatatt
      121 taaattaaat aattatattc tatttacgtt ttcagcttga ggtcctctat taccttgagt
      181 tatatcaaag ctaacctttt cgccttcttc taaagttttg tatccatcat tttgtatagc
      241 tgagaaatgt acgaaaacat catcttctcc ctctacagat atgaacccaa atcctttttc
      301 attgttaaac cattttacta ttccgttttt cattataaga aaacctccgc attattaaaa
      361 aatacaaact aaaaaaataa gtctgttcta ttaatataac ataaatttta aataaaagca
      421 aataaaattt ttaaaaaaat taattacttt tagaatttaa taaaaattgt taaattatac
      481 agtgagaagt attgtaaaat ttgacgaaaa tgtaaatgta gataataaat ttaa
//
LOCUS       DACTZW010000205          500 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.208, whole genome shotgun sequence.
ACCESSION   DACTZW010000205 DACTZW010000000
VERSION     DACTZW010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..500
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.208"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
BASE COUNT          211 a           65 c           86 g          138 t
ORIGIN      
        1 tgaaaatgga agaatattgt atgttactcc agtagtaaat acacttatca aaaatgcaaa
       61 agagatacaa agaacagtaa acataaaaga tggtggaact tctttaaata gacaaaccac
      121 agatattgac acagttaaaa taattaaagt accatctaat ctaatgaaaa ctgcatatga
      181 ttttacaact ggatggaaag taggagcagg agctaaacaa atctttatgt ccttagttca
      241 cccaagtgca ataattacac ctgtttctta tcagttctct aagttagacg aaccaacagc
      301 agttacagag ggaaaatact tctactttga agaaagtttt gaggatgtat ttatattaaa
      361 taaaaaagct gatgcaatac aatttgttgt tgaagcatag aaaaaggagt gatatatagt
      421 gccacaagta aaaaaactaa atagaatact aaccatagaa gaatgtaaaa tagatgattt
      481 cttagagatg ggatatgatt
//
LOCUS       DACTZW010000206          464 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.209, whole genome shotgun sequence.
ACCESSION   DACTZW010000206 DACTZW010000000
VERSION     DACTZW010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.209"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            <1..90
                     /locus_tag="JAM15_19395"
     rRNA            <1..90
                     /locus_tag="JAM15_19395"
                     /product="23S ribosomal RNA"
     gene            268..384
                     /gene="rrf"
                     /locus_tag="JAM15_19400"
     rRNA            268..384
                     /gene="rrf"
                     /locus_tag="JAM15_19400"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            391..462
                     /locus_tag="JAM15_19405"
     tRNA            391..462
                     /locus_tag="JAM15_19405"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:423..425,aa:Asn,seq:gtt)
BASE COUNT          147 a           73 c          103 g          141 t
ORIGIN      
        1 gaaagactat ctggttgata ggtcgaaggt gtaagtgcag caatgtattt agcttatcga
       61 tactaatagg tcgaggactt gaccaatatt atttgatgtt attcattaag atatatgtgc
      121 agtttttaga gtgttaactc tatgtaaagt actaacttca attgatgaag tatatatcgt
      181 aaaaacaatt actatttagt acttcaaaac tattgacatt taaaaataaa gatgttaata
      241 taatacttgt cttataaata ggcaatatgt ggttataata gcaaagagga tacacctgtt
      301 cccattccga acacagaagt taagctcttt agcgctgatg gtacttggtg ggaaactgcc
      361 tgggagagta ggacgtagcc acgtgaatat tccaaggtag ctcaatggtg gagcaaccgg
      421 ctgttaaccg gtaggctgtg ggttcgagcc ccacccttgg agcc
//
LOCUS       DACTZW010000207          457 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.210, whole genome shotgun sequence.
ACCESSION   DACTZW010000207 DACTZW010000000
VERSION     DACTZW010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..457
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.210"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            <1..>457
                     /locus_tag="JAM15_19410"
     CDS             <1..>457
                     /locus_tag="JAM15_19410"
                     /inference="COORDINATES: protein motif:HMM:NF024673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAT6800382.1"
                     /translation="KDYIIEIHKKYRGTYGRKRICTYLNKILDSPINHKKVYRLMKEL
                     GIKSIIRKKVYRRKFKSYEVYDNILNREFRANQPLEKICMDITYIPIGKKFLYMNVAK
                     DLFNGEIVAYEISTKMDTKLVNKTVNQLINMNLAKDCILHTDQGSQYTSR"
BASE COUNT          208 a           40 c           68 g          141 t
ORIGIN      
        1 taaggattat ataattgaaa tacataaaaa atatagagga acttacggta gaaaaagaat
       61 ttgtacttat ttaaataaaa tacttgatag ccctattaat cataagaaag tatataggtt
      121 gatgaaagaa ctaggaatta aatctattat tagaaagaaa gtatatagac gtaagtttaa
      181 atcatatgag gtatatgata atatattaaa tcgtgaattt agagctaatc aaccattaga
      241 aaaaatttgt atggatataa catacatacc tatcggtaaa aaattcttat acatgaatgt
      301 agccaaagat ttatttaatg gtgaaatagt ggcatatgag ataagtacaa aaatggatac
      361 taaattagtt aataaaacag taaatcaact aataaatatg aatttagcta aagattgtat
      421 tttacataca gatcaaggtt cacaatatac aagtaga
//
LOCUS       DACTZW010000208          454 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.211, whole genome shotgun sequence.
ACCESSION   DACTZW010000208 DACTZW010000000
VERSION     DACTZW010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..454
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.211"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            165..>454
                     /locus_tag="JAM15_19415"
     CDS             165..>454
                     /locus_tag="JAM15_19415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAT6800383.1"
                     /translation="MAIDKSYYTIITDVGKAKIANASVTGNKVGFVKIQLGDGGGSEY
                     TPTESQTALKNVVWEGNIGNTTTDETAPNCIILESLIPSSVGGFMIREIGYL"
BASE COUNT          178 a           53 c          103 g          120 t
ORIGIN      
        1 agcaaagaca attatatgaa ttttggtata acaaccttaa tgggtcaaga aataactata
       61 tacccttgga gtccaccaga tatagaaact tatggagaaa ttgatgtatt aactggcaat
      121 ggagttggat accaagaggt aacaatattt taggaggtga tatattggct atagataaaa
      181 gttattacac tataattaca gatgtaggga aagcaaagat agcaaatgca agtgtcacag
      241 gtaataaagt gggatttgta aaaattcaac ttggtgatgg aggagggagt gaatatactc
      301 caactgagag tcagacagct ctcaaaaatg tggtatggga aggcaatatc ggaaatacaa
      361 ctacagatga aactgcacca aattgtataa tattagagag tttaatacca tcaagtgtag
      421 gcgggtttat gataagagaa ataggatatt taga
//
LOCUS       DACTZW010000209          405 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.212, whole genome shotgun sequence.
ACCESSION   DACTZW010000209 DACTZW010000000
VERSION     DACTZW010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..405
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.212"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            27..344
                     /locus_tag="JAM15_19420"
     CDS             27..344
                     /locus_tag="JAM15_19420"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAT6800384.1"
                     /translation="MSKKHKKYSKELKLKAVNLYIKEGYSSYKIAEMLNIRSKTQVQN
                     WVKDYKNKGKTAFNEETRGRFKNISLENDNRKFKSVEEELKYLRMENEFLKKLSTLLD
                     KSK"
BASE COUNT          184 a           40 c           68 g          113 t
ORIGIN      
        1 agcgtatact ctaagggggt ttttctatgt ctaaaaaaca taaaaaatat agcaaagaac
       61 ttaaactaaa agctgtaaat ttatatataa aagaaggata ctcatcatac aaaattgctg
      121 agatgctgaa tataagaagc aaaacacaag ttcaaaactg ggtaaaagat tataaaaata
      181 aaggtaaaac tgcatttaat gaggaaacta gaggcagatt taaaaatatt agtctagaaa
      241 atgataatag aaaatttaaa tctgttgaag aagaattgaa gtacttacgc atggagaatg
      301 aatttttaaa aaagttaagt accctattgg acaagtcaaa gtaagcgata aatttaaaac
      361 aattaaactt atgtctagga agtatagtat ttctagtatg tgtaa
//
LOCUS       DACTZW010000210          374 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.213, whole genome shotgun sequence.
ACCESSION   DACTZW010000210 DACTZW010000000
VERSION     DACTZW010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..374
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.213"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            <1..>374
                     /locus_tag="JAM15_19425"
     rRNA            <1..>374
                     /locus_tag="JAM15_19425"
                     /product="16S ribosomal RNA"
BASE COUNT           89 a           88 c          107 g           90 t
ORIGIN      
        1 acaggtggtg catggttgtc gtcagctcgt gtcgtgagat gttgggttaa gtcccgcaac
       61 gagcgcaacc cttgtcttta gttgccatca ttaagttggg cactctagag agactgccag
      121 ggataacctg gaggaaggtg gggatgacgt caaatcatca tgccccttat gcttagggct
      181 acacacgtgc tacaatgggt agtacagagg gttgccaagc cgtaaggtgg agctaatccc
      241 ttaaagctac tctcagttcg gattgtaggc tgaaactcgc ctacatgaag ctggagttac
      301 tagtaatcgc agatcagaat gctgcggtga atgcgttccc gggtcttgta cacaccgccc
      361 gtcacaccac ggga
//
LOCUS       DACTZW010000211          333 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.214, whole genome shotgun sequence.
ACCESSION   DACTZW010000211 DACTZW010000000
VERSION     DACTZW010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 333)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 333)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..333
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.214"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
BASE COUNT          145 a           30 c           35 g          123 t
ORIGIN      
        1 ttgaattgtc attaaatatg ccaatagttt tatatattat tgattttatt aaaaaaagag
       61 atatacaaac taataagttg taatctctca aatataaaaa aacaataaat taactcattg
      121 gattttttag tccataatat aattatagat tattcaacaa acaatctata gaaattgtgg
      181 tattaatgtt taaataacca actttttcta aaataacctt tataggaata tatgagttca
      241 taagtaaaga tagcgaaata agaaaccagt ttggtatgta aaatctagat ttttaattaa
      301 attatcaaga ttatatgtta tagtatcaaa aat
//
LOCUS       DACTZW010000212          322 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.215, whole genome shotgun sequence.
ACCESSION   DACTZW010000212 DACTZW010000000
VERSION     DACTZW010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..322
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.215"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            complement(<1..241)
                     /locus_tag="JAM15_19430"
     rRNA            complement(<1..241)
                     /locus_tag="JAM15_19430"
                     /product="23S ribosomal RNA"
BASE COUNT           90 a           74 c           49 g          109 t
ORIGIN      
        1 tacggaatcg aatttctttc tcttccttca ggtacttaga tgtttcagtt ccctgagttc
       61 ccctcattaa gctatgtatt cacttaatga tacttagaca ttactctaag tgagtttcct
      121 cattcggaaa tcttcggatc aaagtttacg tgcaactccc cgaagcttat cgcagcttat
      181 cacgtccttc atcggctcct agtgccaagg catccgccct gcacccttaa taacttgacc
      241 agttaaaaag gtttgataga ttagaagcta tcaacttcga taattttaaa aagttatcag
      301 ctttatatat tacaaattag at
//
LOCUS       DACTZW010000213          320 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.216, whole genome shotgun sequence.
ACCESSION   DACTZW010000213 DACTZW010000000
VERSION     DACTZW010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..320
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.216"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            133..>320
                     /locus_tag="JAM15_19435"
     CDS             133..>320
                     /locus_tag="JAM15_19435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAT6800385.1"
                     /translation="MIDVKKLYFSYTDKPFVENVSFHVGRGEIFGFLGPSGAGKSTIQ
                     KILTGLNTSYKGSVKVAGT"
BASE COUNT          113 a           36 c           66 g          105 t
ORIGIN      
        1 gtattattca gcaagtagta gcagagtaat aattttgttt ggttatttga caggcaagtg
       61 gccaaacaaa ttttttacag tttatatgac tatatatcta taaacgtcat aaagttaaag
      121 gaggaaagaa taatgattga tgtaaaaaaa ctgtatttta gttatactga caaaccgttt
      181 gttgagaatg taagtttcca tgttgggaga ggagaaattt tcggtttttt aggaccctct
      241 ggtgctggaa aatcaactat tcaaaaaatt ttaactgggc ttaatacaag ttataaaggc
      301 agcgtaaaag ttgcaggtac
//
LOCUS       DACTZW010000214          310 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.denovo.217, whole genome shotgun sequence.
ACCESSION   DACTZW010000214 DACTZW010000000
VERSION     DACTZW010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..310
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.denovo.217"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            <1..>310
                     /locus_tag="JAM15_19440"
     CDS             <1..>310
                     /locus_tag="JAM15_19440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HAT6800386.1"
                     /translation="EIAAYLFEIMKANATLESCDLAICLYSQKDEKGIAILKLDYNNS
                     YTHSIEFKEDKFNIQMSKNEINIQETKTVKIATLIGLSGMNDEYHLRVLDKDAEKEEA
                     N"
BASE COUNT          122 a           35 c           60 g           93 t
ORIGIN      
        1 agaaatagca gcttatttat ttgagattat gaaagcgaat gctacattag aatcttgtga
       61 cttagcaatt tgcttatact ctcaaaaaga tgaaaaggga attgctatat taaagcttga
      121 ttacaataat tcgtatactc attcaatcga gtttaaagag gataaattta acatacagat
      181 gtctaaaaat gaaattaata tacaagagac taagacagtc aaaattgcca ctttgattgg
      241 cttgagtggg atgaatgacg agtatcattt aagggtttta gataaggatg cagaaaagga
      301 agaagctaat
//
LOCUS       DACTZW010000215        13791 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.guided.103, whole genome shotgun sequence.
ACCESSION   DACTZW010000215 DACTZW010000000
VERSION     DACTZW010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13791
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.guided.103"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            207..824
                     /locus_tag="JAM15_19445"
     CDS             207..824
                     /locus_tag="JAM15_19445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800387.1"
                     /translation="MCKKTYLLVVSILIAGLLTACSGSPTKDSGQAQDNTKKEANASN
                     NALKDEKNNENLMEQDFKVPYTDAINIFKDKYKDADIVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTEKLDSEDLNGVARKEKLDLNDIITPQQAMEIALKEQNG
                     MVKEWSLDKDLDVTFYKIRIDKDKNEYDIKVDSKKGTVLKVEKED"
     gene            932..3463
                     /locus_tag="JAM15_19450"
     CDS             932..3463
                     /locus_tag="JAM15_19450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAT6800388.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIKE
                     DKTLVTCDSFGSHYSNDKIVNTLDENEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVKEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKPIWDILISL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNEEIDKLHSY
                     TGKFLDKLNSTFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFIEVEEDEVT
                     FRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVV
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVFKDGDSVDC
                     DMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNVKDIYACGDVAQVGNIGLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFDDIMKADIL"
     gene            3897..4598
                     /locus_tag="JAM15_19455"
     CDS             3897..4598
                     /locus_tag="JAM15_19455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanG-Cd-type vancomycin resistance DNA-binding
                     response regulator VanS"
                     /protein_id="HAT6800389.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KNLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            4648..5730
                     /locus_tag="JAM15_19460"
     CDS             4648..5730
                     /locus_tag="JAM15_19460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAT6800390.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGMDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFINRSNTIPEEKLERIFEQFYRLDISRNSNSGRAGVGLAIAKEIVEL
                     HNGTITAHSENNIITFKVIIPIVGNL"
     gene            5991..7091
                     /locus_tag="JAM15_19465"
     CDS             5991..7091
                     /locus_tag="JAM15_19465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HAT6800391.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDILPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLISDAVSQNHIPNS
                     AIESCENNIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKIPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNDDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            7088..7894
                     /locus_tag="JAM15_19470"
     CDS             7088..7894
                     /locus_tag="JAM15_19470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HAT6800392.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRIFIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            7912..10050
                     /gene="vanT"
                     /locus_tag="JAM15_19475"
     CDS             7912..10050
                     /gene="vanT"
                     /locus_tag="JAM15_19475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HAT6800393.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYNKMADFVLTSII
                     ARIAVPFFFMLSGFFLISKYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKKLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYVFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGPRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKD
                     LKGEQKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCKLMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSSPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSASEVANNSCSISNELLSRVGRRLNVIKK"
     gene            10364..10984
                     /locus_tag="JAM15_19480"
     CDS             10364..10984
                     /locus_tag="JAM15_19480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAT6800394.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHHNDKDDKMI"
     gene            complement(11150..11686)
                     /locus_tag="JAM15_19485"
     CDS             complement(11150..11686)
                     /locus_tag="JAM15_19485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HAT6800395.1"
                     /translation="MIKETHERGGYIFALLILPFINNLYLVKYDIAYKIVLIIIYIYF
                     AYLGSLFPDIDMRGSYISKKFMLIYKLFGSRFRHRGFTHSLIALLLIYSFFKSLTIFT
                     NNNIVFSCLSSGFIIGYLSHLCLDLITKEGIELFYPITINISLLPIKTNSKTEKFISK
                     LLNFIVIFLIGYQFYILL"
     gene            complement(11799..12503)
                     /locus_tag="JAM15_19490"
     CDS             complement(11799..12503)
                     /locus_tag="JAM15_19490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HAT6800396.1"
                     /translation="MKKKILIPVIMSLFIISQCITSFAFTPENNKFKVKPLPYAYDAL
                     EPYIDKETMKLHHDKHYQAYVDKLNAALEKYPELYNYSLCELLQNLDSLPKDIATTVR
                     NNAGGAYNHKFFFDIMTPEKTIPSESLKEAIDRDFGSFEKFKQEFQKSALDVFGSGWA
                     WLVATKDGKLSIMTTPNQDSPVSKNLTPIIGLDVWEHAYYLKYQNRRNEYIGNWFNVV
                     NWNGALENYKNLKSQD"
     gene            12675..>13791
                     /gene="asnB"
                     /locus_tag="JAM15_19495"
     CDS             12675..>13791
                     /gene="asnB"
                     /locus_tag="JAM15_19495"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HAT6800397.1"
                     /translation="MDGNISIYYKGDISKKENIKFKIKESVNNTRLSSRIEYKDEEKT
                     FDFERFNVIDAIYGNKPFEKDGKVIVFNGNIYNYHEIKEELIKKGHNFTTNDDIEVLL
                     ASYIEFGKNCVHKIKGMFNFIIYDRENESIFGARDLFGIKPLYYINKENAIIFSSEYK
                     FLLEYMKNLNINERSLQSYFSFQYVLPEDTMIQGIRLIPAGHYFRVENGILSLKRYNK
                     LEFRSSTKFFYTKNHLGNRDVNEDDIRNIVVDSIVTHMEEEKEIGTFLSGGIDSSIIT
                     TVASQINPNIKSFSAGFSVKGYSELEVAKKTADKLGIENIQINITQDEYIKSLPDVIY
                     SLDDPIADPSEVGLYFLIKEAGKHVKVALSGEGADELF"
BASE COUNT         5271 a         1454 c         2372 g         4694 t
ORIGIN      
        1 cgaaataaaa tatattttta ttatttcaac aatgaaaaag atgcttgttt ctattttgag
       61 acagtataat ttttatgtaa ctttaatttt agtaaatata aagttttaaa attgataaaa
      121 taggaggaat ttttaatata aaagggtaaa taaagggttt agagggcata atatagaata
      181 aattaatata tttaaggagg atttttatgt gtaaaaaaac gtatttatta gtggtaagta
      241 tacttatagc aggtttatta actgcatgta gtgggagccc aactaaggat tcaggacaag
      301 cacaagataa tacaaaaaag gaggcaaatg cttcaaataa tgctttaaaa gatgaaaaaa
      361 ataatgaaaa tttaatggaa caagatttta aagtgccata cacagatgca ataaacatat
      421 ttaaagataa atacaaggat gctgatatag tagatttaag tcttgagaga gatttaaata
      481 aatttgttta tactgtggaa ggtgtagatg ataataatga atataagatg aaaattgatg
      541 ctaatacaaa agatgtatta gaagataaaa cagaaaagtt agattcagaa gatttaaatg
      601 gagttgctag aaaagaaaaa ttagatttaa atgacataat tacacctcaa caagctatgg
      661 aaattgcatt aaaagaacaa aatggaatgg ttaaagaatg gagtttagac aaagatttag
      721 atgttacttt ttataaaata agaatagata aagataaaaa tgaatatgac ataaaagtag
      781 attctaaaaa gggaactgta ttgaaggtag aaaaagaaga ttagaagatt taaactatct
      841 ttaaaataat ttcttttttg aataaatttt gtttaaaata taacaagcag ggtataaaga
      901 gactaaataa ctattttagg aggagtacgg tatgtcattg aaatcactaa aaataaaaga
      961 aaatttatat tgggtaggtt cacttgaccc tgatttaaga gtatttgaca taattatgta
     1021 tacaccttat ggaactactt ataattcata tgtattaaaa ggaacagaaa aaacagtttt
     1081 gtttgagaca gttaaagata agcattttga caattatatt gaaagattaa atgatttaaa
     1141 tatagatttt gaaaaaatag actatattgt tgtaagtcat actgaaccag accatgcagg
     1201 aagcgttgaa aagcttttgg atttagctaa aaatgcaaaa gtagtagctt cagaaacagc
     1261 aattaaatat cttaaggaaa tcgtaaacaa agactttgaa tatgttgcag ttacagatgg
     1321 agatacatta tcaattgggg acaaaacttt agaatttttc tctgtaccta tgcttcattg
     1381 gccagatact atatacacat atataaaaga ggataaaact cttgtaacat gtgattcatt
     1441 tggtagtcac tatagtaatg ataagatagt aaatacactt gatgaaaatg aagaaaagga
     1501 ttacttggat gctttaagat actattatga ttgtataatg ggtccattta aaccatctat
     1561 ggtaactgct atagaaaaga taaaagattt agatatagat actgtatgtc caggtcatgg
     1621 tccagtatta actgaaaatc ctagaaaaat tatagacctt tattataact ggagtgtaaa
     1681 ggaacaaata aagttagaaa aagaagttac aatttgttat gtttctgcac atggatatac
     1741 aaagattatg gcagaagcta taaaagcata tattgaaaaa aatagcaact ataaagtaaa
     1801 tttatttgat gtaatagagc ataagcaaga agatattttg gcaaaaatag cagtatcaca
     1861 aggtgtatta tttggaacac caacaatatt aggagatgcg ttaaagccta tatgggatat
     1921 attaatatcg ttaaacccag ttcttcatgg tggaaaagtt gcttcagtat ttggttcata
     1981 tggatggagt ggagaaggca tagaaaatgc tatggagaga ataagtcagc ttagaatgac
     2041 agcagtaaaa ccttttgctg ttaactttaa accatcaaat gaagagattg ataaattaca
     2101 ttcttataca ggtaaattcc tagataagtt aaattctact tttggaagta aaaagaaaac
     2161 taagaaattt aaatgtgtaa tttgtaatga agtttttgaa ggtgatagtg ctcctagtgt
     2221 atgccctgta tgtggagcta aggaagacca atttatagaa gttgaagaag atgaagttac
     2281 ttttagaaaa gatactgatg aatatttcgt aatagtagga aatggagcag ctggttttta
     2341 tgcagcagat gctataagaa aaagaaataa aacttgtaag ataactatga tttctaatga
     2401 agatgagttg acttactata gacctgcact ttctgatggt ataaatgaag aacttggttc
     2461 agatttctac atggaagata aagattggta tgataaaaat aatatagtag taatattagg
     2521 aacgaatgta gataaattag atgaggtgaa taaaactatt atagtgaatg atggagctat
     2581 taaatttgat aagcttgtaa tagctacagg aagtagaaac tttataccac caattaaggg
     2641 tcatgattta gaaaatgtgt ttactcttag aaatataaaa gatttatata gtgtaaaaga
     2701 agcactagaa aaatctaaga aagttgtagt gattggtggc ggtttattgg gacttgaagc
     2761 tgcatgggaa tttagactaa aaggattaga agtagtagta gttgaagcca tggatagcat
     2821 actatcaaaa caacttgata aagaaggtag taaaatatta gaacaatgtg taagagatac
     2881 aggaatagat gtaagattgg gtgtagcagt tgatggtatt gaaggtgatg gaaaagctca
     2941 aaaagttgta tttaaagatg gagatagtgt cgattgtgat atggtagtat tttcaattgg
     3001 tgtaagagca aacactcaaa tggttcagga tacatctgta aaaattgaca gaggtattgt
     3061 tgtagataag acattacaga caaatgttaa agatatatat gcttgtggag atgttgcaca
     3121 agtgggaaat attggtttag caatatggcc atcttcagta gaaatgggaa aaatagcagg
     3181 ggcaaatgca agtggagata atttgacatt tgaaagtgaa gtatatccag tttcattaga
     3241 tgcaatgaat gtaaaagtat ttagtattgg taatatacaa aattttgata aagaaatttc
     3301 atcaaaagat gaaggtcaaa gaatatataa aaaattattt atgaaagatg gttcattagt
     3361 tggagctata cttataaatg atttaagctg tactgttaaa ttgataagat taatatctga
     3421 aaaaggtgat tttgatgata ttatgaaggc tgatatacta taatttaaat acattaaaat
     3481 aaaaaggagt tgtctcaaaa ttgatttttt tctaatcaaa ttttaaattc aactcctttt
     3541 ttgaattttt atataaaata acatggaaat tttagtaatg tctgtggtta catacatagg
     3601 tttaattgtt ttttatatgg attgtctctg gtataataaa ttgaattgtg tttgactgat
     3661 agatattttt attgaaagtt aatacctgtt atgcgataat aaggacgtgt taggggagtt
     3721 tttataataa caattaatct tagtttttgt gttccaatag tagcatcaac acattctgat
     3781 gtagtagttc ttttcttata aaaattagtt acaaatatgc ttgtaattat ttgatatgta
     3841 aatttaccaa tattataaat gatgacctcg ataataagga gagtgaaaaa taatctatga
     3901 acgaaaatat tttgattgtg gatgatgaaa aagaaatagc agatttaatt gaagtatatt
     3961 taaaaaatga aggttttaca gtatacaagt tttatacagg taaggaagct ctagaatgta
     4021 ttgaatctaa aaatttggat atggctattt tagatattat gcttcctgat attgatggat
     4081 ttcatatttg ccagaaaatt cgagaaaaat actattatcc tatcattatg ttaacagcta
     4141 aaattgaaga tatagacaag ataatgggtt taaccatagg tgctgatgat tatataacaa
     4201 agccatttaa ccctttggaa gttgttgcaa gagtaaagac acaattaaga agatatatgc
     4261 gatataataa ttcttatgaa caacagtcga taattgttaa tgagtatgat attaaaggat
     4321 tgattatcaa taaagaaaca cataaatgta gtttatttgg gaaagaagta gcattaacac
     4381 cgattgaatt ttctattctt tggtatttat gtgaacatca aggaaaagtg gttccttctg
     4441 aagaattgtt tgaagctgta tggggagaaa aatatcttga taataataac acagttatgg
     4501 ctcatatagg gcgattacgt gaaaaaattc atgaaccttc taaaaacccg aaatttataa
     4561 aaactgtatg gggagtaggt tatacaattg aaaagtaaaa atattaaagt caatcctgac
     4621 tttgctcaag tgagaaataa aatttttatg agaacagctt taatggcatt tatagccatt
     4681 attttcatat ggattttata ttcttttata ttgtatggta agttttctat ctggatagta
     4741 tcattctttg aaaatgcttt tcgtatggaa tataaagctg cattgaattt atatcagcag
     4801 attttccgta atagcatgga gctcttcatg atactagcta tggtgattgt gttttttata
     4861 atattccgtg tttatttaaa ttggtttaca aaatatttta gtgaaataaa tcaaggtatg
     4921 gactctctta tcaaagaaga tgttggagaa gtggctttat ctccagagtt attggcaata
     4981 gaaaagaaaa taaactcaat taaacatata cttgaacaac gtaaatttga gacacaaatg
     5041 gcagaacaac gtaagaatga acttattgtt tatcttgcac atgacttaaa aacaccactt
     5101 acatcagtta taggatatct gacactactt cgagatgaaa gtcagatttc tgaagaactg
     5161 cgaaaaaaat atttatctat ttcgttggat aaggcagagc gtcttgaaga tttaattaat
     5221 gaattctttg aaattacaag gtttaattta tcaaatatat cacttgaata cagtacagta
     5281 agcttaactc gtatgcttga acaactaaca tatgagttta aacctacttt gatgagtaag
     5341 aatttaaaat atacactgaa tgttacacca aatatgatga taaggtgtga tgttaataaa
     5401 atgcaacgtg tatttgataa cttattacga aatgctgttt attatagttt tgaagatact
     5461 actattgaaa taacagctgt acaggaggat gattatataa agcttaaatt tataaatcgt
     5521 agcaatacga ttccagagga aaaacttgag cgtatttttg aacaatttta caggttggat
     5581 atatctcgta attcaaacag tggtagagct ggggtgggac ttgctatagc taaagaaata
     5641 gtggagcttc ataacgggac aataacagct catagcgaga acaatataat tacctttaag
     5701 gttattattc cgattgtagg aaatttgtaa gaatttaagt ataaaaaaat aggaaattct
     5761 ttaggataaa taaataaaga gcactcttgt tattgatata attactgtat caaaacaaga
     5821 gtgcttttat tttgatacag taattatatc aatagaaaaa tgtgaaaata tattatgtgg
     5881 aacagatgca attgtaagtg aaggttgatt ggatttgaaa tagaaaaagt attttaacat
     5941 gtttctgtag attgtataaa aataaataaa tcaacaaagg agaatcaaag atgaataata
     6001 aaaaaattgc agttatattt ggtggaaact caacagaata tgatgtatca ttacaatcag
     6061 cttttgcagt acttgagaat ttgaatacgg aaaaatatga tattctacca attggaatta
     6121 caagggaggg taattggtat cattatattg gagattataa taatatccag aataacactt
     6181 ggtttgaaag ggatactgat ataattccag ttattgtttc gcagaaccgt gtcaaaaatg
     6241 gtattattga atttttaatt tctgatgctg tttctcagaa tcatattcca aatagtgcta
     6301 ttgaatcatg tgaaaataat attaaataca ctaaacttga ttttgtattt cctgtattgc
     6361 atggaaaaaa tggagaagat ggaacagtgc aggggttatt tgaattggca ggtatacagg
     6421 ttattggatg tggtactctt tcttcagcat tatgtatgga caaagacaaa tcacataaac
     6481 ttgttcattc agaaggtatt aaaataccaa aatcaatatt actaaaatac tcagataaat
     6541 ttaatgtggc tgaactgtca aaagacttaa cttatccatt atttataaaa cctgtgcgtg
     6601 caggttcatc atttggtatt agtaaaattt ataaaaaaga agagttacaa gtagcagtag
     6661 acttggcttt tgaacatgat aatgaagtaa taattgagga aaatattgat ggttttgagg
     6721 tagggtgtgc agttttagga aacgatgact tacttgttgg aagagtagat gaaatagaat
     6781 tgtcaaaagg attttttgat tatacagaaa aatatacatt gaaaagttca aaaattcata
     6841 tgccagctag aattgatttg gattgtgaga aaagaataca agagacagca aaaattattt
     6901 atagaactct tggatgttct ggatttgcta gagtagatat gtttttaact ccatctggtg
     6961 aaattatttt taatgaagtt aatacaattc ctggctttac ttctcatagt cgttatccga
     7021 atatgatgaa aggtattgga ttgtcttttg aagaaatatt ggacaagata attgaggtgt
     7081 atataaaatg atgaataata ttttattaga taaaaataaa gaagataaaa tgacaaatac
     7141 tatcttattg actaaagata aagtttatga tgggaatcta attctagtaa atgctttttt
     7201 accagttaaa acatctgaag atatagattt aattcctgta gatacaaggt ttccaagtat
     7261 tcttatgaaa cgtgaagcta caaatatttt gcaaaatatt ttaaaaagta tatgtggaat
     7321 aaatgaaata gtacctgtaa gtggatatcg tactgcagag gaacaacaag atatatattc
     7381 aagttctctg cgtgacaatg gaaaagactt tactaaaaag tttgtagcac ttccaaatca
     7441 cagtgaacat cagacagggc ttgctattga tttagggttg aagaaagagg ttatagattt
     7501 tatctgccct gaatttcctt ataatggtat ttgtaatgag ttccgtaagg cagcactaca
     7561 ttatggtttt atagagcgtt atcagtgtaa aaaagaagaa ataacaggaa tatctcaaga
     7621 accatggcat tttcgttatg tcggatatcc acattctgag attatcaata aaatgaatct
     7681 cgcccttgaa gaatatatag aatatattaa gagattttcg tatacaaatt gtttaaaaat
     7741 agaggataaa gaaaaaatta tagaaatctt ttatgtgcct attcatacta aagaagaagt
     7801 gagaatcttt atacctgaac aatgtgtcta tcaaatatcg ggtaacaata aggatggttt
     7861 tattgtgaca ttttggagaa atagaaagga ctaagaaatg gaggaacaag aatgattagg
     7921 aataaatctt atgcagggct tgattatttt aggattatag ctgcattact tataattgca
     7981 attcatacat ctccattatt atcatataat aaaatggctg actttgtgtt aactagtata
     8041 attgctcgta ttgctgtgcc attctttttt atgctatcag gcttttttct aatttcaaaa
     8101 tataattata attgtaataa actgaaatct tttctaaaaa atgtattatt tatttacggg
     8161 atagctattg taatttatat tcccttaaat atttacactg gatatttttc catgaataat
     8221 ttagtgccca atattattaa ggacattgta tttgatggga ctttatatca tttatggtat
     8281 cttcctgcat caattattgg tgcaagtatt gcatactttc ttgtaaaaaa actaggttta
     8341 aagtactcac tagtaatcac tattgttatt tatgtaattg gtatgtttgg tgatagttat
     8401 tatggttttt tagaaaaaat accattatta aagaatttat atgggtatgt ttttgaagta
     8461 tcagattata cacgaaatgg tatatttttt gcacctgtat ttttcatact tggtggaata
     8521 atatctaata aatctaatta tatgtcaact aaaaatagct tgattggatt tcttatatca
     8581 ttcttactta tgttatgtga gggaatgttt ttacataaac taggggtaca gcgtcatgat
     8641 agcatgtata ttatgttatt gccatgtatg tattttttat ttacagcttt aacatttttg
     8701 aaaggtcctc gagctaggtt attacgaaca tcatcattaa ttatttatat tatacatcct
     8761 atgatgattg ttgttattcg tatgttttct aaaatattcg gaatacaaac tgtcttggtt
     8821 gacaatagcc ttattcatta tatagtggta agtatagcat cttttatagc ttctataatt
     8881 attatattga ttcttaaacc tctaaaaaaa gacttgaaag gagaacagaa ggtaaatacc
     8941 aatagagctt ggattgaaat tgatttaaat aatttggaac ataatgtaaa gatgatacaa
     9001 aaagctatgc cagaagattg taaattgatg gcagttgtaa aagctaatgc ctatggtcat
     9061 agtgcttttg aagtagcgac ttgtgcaaac caaataggtg taaaagcatt tgcagtagca
     9121 acaatagatg aggggattga tttacgtcga tatggaatac taggagaaat attgattctt
     9181 ggatatacta acccaataag ggcaaaggaa cttcataaat acaatcttac acagagtgtt
     9241 attgacctta atcatgctat ctctttaaac aaacagaaat acaacataaa atcacacatt
     9301 aaaattgata caggtatgca cagactgggt tttgatgtta atgatgtgag gtcaatttta
     9361 aaggcattta aattaaaata cttagatata tgtggcatat ttacacactt gtgtgtttca
     9421 gatagtctga aagatgaaga tgtagacttt acaaataaac aaattgaatg tttttataag
     9481 ttaattgatt ttctgttaaa aaaaggtata aaaattccta aagtacatat tcaaagtagt
     9541 tatggttttt ttaattatcc caatcttaag tgtaattatg taagaattgg aattgcatta
     9601 tacgggatat taagttctcc aaatgatacg actaaattgc aacttgattt acgacctgtt
     9661 ttatccttaa aatcacaagt aattcttatt agaaaaatac aaaaagatga tagttttgga
     9721 tatggaagag tctttattgc aagcagagat agcgtaattg ctatattatc tattggttat
     9781 gccgatggta tacctagaaa tttatcctgt ggaaaaagtt acgtaataat aaacggttgt
     9841 agagcagcaa tagtgggtcg aatttgcatg gaccaacttg ctgttgatat tacagatata
     9901 cctaatgtag aagttggtaa tacggcaata ataataggaa gagataattt atctgaatta
     9961 tctgcttctg aagttgcaaa taactcatgt agtatatcga atgaattatt gagcagagta
    10021 ggaagaaggt taaatgttat aaagaagtaa ctcaattaaa tagtaatatt tgttgtactg
    10081 tgtaatttat tttactctga ctagacattt ttagtaatat tatgtctaat atatattttt
    10141 tataacttat atgacaattt aagttataaa aaggtgatgt ttcagatttt tattttgaaa
    10201 catcaccttt tttgttataa tatataataa aataattata ccttaactgt aaatttatat
    10261 agagtattta ctttttatta taagattcat tttttgagat tggtatataa taaacatata
    10321 gagtatataa taatagttaa agttaaaaaa ggggaaaagc aatatgcagt atatacaaga
    10381 attacttgat ttgactcaaa attattgggt gttagccaca ataatcggct tattaagtgc
    10441 atttatagaa agctttatac cagccttacc acttgttgct atagttacag caaatgctgc
    10501 aatacaagga ttatttattg gatgtttgtt atcatggatt ggctcaggac ttgggacaac
    10561 ttcattattc ttattaataa gcagatttaa tgatagtaag ctttttaata agttgagaaa
    10621 tagtaaaact gaaaaagcaa taagttggat ggataaacag ggatttaagt tactatttat
    10681 agcgtatgcc tgtccattta tgcctggttg tttagttact atcgcatcag cttttggtaa
    10741 aaaagattta aaagattttg tgccagcaat gttggcagga aaatttgtaa tgtttatagt
    10801 tataagttac gtggcaagtg atatagaagg ttttataaca agtcctttaa agatagcatc
    10861 atttatatta ttggtgtttt tgtcatggaa gattggaaat agagtaaata aaaatcttga
    10921 aaatcataat tatgatttcc atcataaaaa acatcacaat gataaagatg ataaaatgat
    10981 ttagcttgta ctaaataaaa cgtatcttaa aatgatttag tactaaatta ttttaagata
    11041 cgttttattt tttgtattaa ggtacaaaat ttttagttat tttgtaaact aaaatatata
    11101 aaacttattt atacttagtt caaaatattg ttatttattt tttctacaac tataataaaa
    11161 tataaaattg atatccaatc aaaaaaataa ctatgaaatt taatagctta gatatgaatt
    11221 tttctgtttt tgagttagtt tttataggta gtaaagaaat gtttatggta atgggataaa
    11281 acaattcaat accttcttta gtaataaggt caagacacaa gtgagataga tatcctatta
    11341 taaacccact ggataaacat gagaaaacta tattattgtt agtgaagatt gtcagagatt
    11401 taaaaaaact ataaataagt aataaggcaa ttagactgtg agtaaaccct ctatgtctaa
    11461 acctacttcc aaataatttg tatattaaca taaatttttt acttatgtaa gaacctctca
    11521 tatctatatc tggaaataaa gaacctaaat atgcaaaata aatataaatt ataattaata
    11581 ctattttata tgcaatatcg tatttaacta ggtacagatt gtttataaag gggagtatca
    11641 aaagtgcgaa tatataacct cccctttcat gtgtttcttt tatcatataa aaatcctcct
    11701 gaatcgtcac tataaacatt atattggtaa atttagacta tcttttatta tattatatag
    11761 caaacataag tttttttcaa aaggatttta atatttaatt aatcttgaga ttttaaattt
    11821 ttgtaatttt ctaaagcacc attccaattt actacattaa accagttgcc aatgtattca
    11881 tttcttctat tttgatattt taaatagtaa gcatgctccc aaacatcaag tcctattata
    11941 ggagttaggt ttttacttac agggctatcc tgatttggag tagtcataat agataatttc
    12001 ccatctttag tagctacaag ccaagcccaa ccagaaccaa agacatctaa agcagatttt
    12061 tggaactctt gcttaaattt ttcaaaagaa ccaaagtctc tatcaatagc ttcttttaaa
    12121 gattcagaag gtatggtttt ttctggcgtc attatatcaa aaaagaattt atgattataa
    12181 gctccacctg cattatttct tacagttgta gcaatatctt taggtaaaga atctaaattt
    12241 tgcaataatt cacataaaga ataattataa agctcaggat atttttcaag agcagcattt
    12301 aatttatcaa cataagcttg ataatgctta tcatgatgca gtttcattgt ttctttatct
    12361 atataaggtt caagtgcatc atatgcataa ggtaatggtt taaccttaaa tttgttattt
    12421 tcaggtgtaa aagcaaatga agttatgcac tgtgagatta taaataaaga cataataact
    12481 ggtattaata tttttttctt cataaaaatc acctcctaat atagtatttc tagaaataaa
    12541 aaaatatgaa atattaacag ataatttata agaatttaat agcaatttca ttttaaattg
    12601 aataagtttt aaagccaaag acaaaactat gaaatataga ataagactaa atgacagaaa
    12661 ggaattttga ttatatggac ggcaatattt caatttatta taaaggtgat atatctaaaa
    12721 aagaaaatat taaatttaaa ataaaagaat ctgtaaataa tacaagactt tctagtagaa
    12781 tagagtataa ggatgaggaa aaaacttttg attttgaaag atttaatgta attgatgcta
    12841 tttatggaaa taaaccattt gaaaaagatg gaaaagttat tgtttttaat ggaaatatat
    12901 ataactatca tgaaataaaa gaagaattaa ttaaaaaggg acacaatttt actacaaatg
    12961 atgatattga agtcttattg gcatcttata tagaatttgg taagaattgt gtacataaga
    13021 ttaaaggaat gttcaacttt ataatctatg atagagaaaa tgaaagtata tttggagcaa
    13081 gagatttatt tgggataaaa ccactttatt atataaataa ggaaaatgca ataatttttt
    13141 cctcagagta taagttttta cttgaatata tgaaaaattt aaatataaat gaaagaagct
    13201 tacaaagtta tttttcattt caatatgtac ttcctgaaga tactatgata caaggaataa
    13261 ggctgatacc agcaggtcac tattttaggg tagaaaatgg tatactatct ttaaagagat
    13321 ataataaact tgagtttaga agtagtacaa aattttttta tactaaaaat cacttaggca
    13381 atagagatgt gaatgaggat gatataagaa atatagtagt agattcaata gtaactcata
    13441 tggaagagga gaaagaaatt ggaacatttc tgtctggtgg aatagattca tctattataa
    13501 ctactgtggc ttcacaaatt aatccaaata taaaatcttt ttctgcaggc tttagtgtca
    13561 aaggatatag tgaattagaa gtagcaaaga aaacagctga taagttaggt atagaaaata
    13621 tccagattaa tataacacaa gatgaatata taaaatcatt accggatgta atttattctt
    13681 tggatgaccc tatagcagac ccttcagaag taggtcttta tttcttaatt aaagaggcag
    13741 gtaaacatgt taaagtagca ttgtctggag aaggagcaga tgaattattt g
//
LOCUS       DACTZW010000216         8087 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.guided.129, whole genome shotgun sequence.
ACCESSION   DACTZW010000216 DACTZW010000000
VERSION     DACTZW010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8087
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.guided.129"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            14..730
                     /locus_tag="JAM15_19500"
     CDS             14..730
                     /locus_tag="JAM15_19500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800398.1"
                     /translation="MILIVILSIFIIASINIIILGKENIRDIVIPLTLFIVSDFLFLC
                     GNIICRGGVMLLFIGLFAIPLMLIAFIWICVHMIKLYYKKDLNKRKMIGCIFSIFISI
                     GTIFIPSPSESFRFKLYEKDYSVVAKAILKVYDEKKLSSESVFYIQSDKNELEKIFSK
                     EVIKKMKKLNRNLDVVKISGNRNLVYFFFGAELQSIDGIVIFKDLKHVKPKLDFINRS
                     IQAPRLEYITNNVYYFKGEL"
     gene            758..1696
                     /gene="blaCDD"
                     /locus_tag="JAM15_19505"
     CDS             758..1696
                     /gene="blaCDD"
                     /locus_tag="JAM15_19505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HAT6800399.1"
                     /translation="MKRKNNFIWIVILLVVVAMGVYYVGRKHNNTKQKHDKNHINSEL
                     NKSKVENNDKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETRRSPCS
                     TFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYYKKLID
                     KVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQTMAKI
                     FEGDTNFKKEHINILRDIMKIDVNDKNINVYGKTGTGFDEKNKRVDAWFVGMLEREGD
                     TYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            2040..2723
                     /locus_tag="JAM15_19510"
     CDS             2040..2723
                     /locus_tag="JAM15_19510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAT6800400.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTSGKIYVEDTEISSLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            2720..5380
                     /locus_tag="JAM15_19515"
     CDS             2720..5380
                     /locus_tag="JAM15_19515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAT6800401.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIRLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWNSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGDRI
                     LNGKPLEPIAQKSKGESFKKISETTLTIVGKVDVSTSSVIPAYTALGYLDRTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKMS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYINSVNYHTDVPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIAVYLENSEPVE
                     SAFIEKLDNTEGVKSSLYYQKMSASTWLTEKDASKELAKNGGFKSIVSSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYCRQISVDPKLFYDTKNPTSIVYNKEEDINRSTRRNKVY
                     IDYLNLSIGDNIKLNEKVYDEDKGDYTYNMKVGAITSTLPKIVDTSSKYTLMQIVPMS
                     MVQEISKNYDEVSRLRSNRLIGVFKVNNREDIPRVREKLESIYNKDYGSGDYSIEDVL
                     ESEKQKASGIKTMNLIVGFITGLLAMIGLSNVLATVSGNIRSRRQEFAMLRSVGLSPE
                     GIKKMLVLEGLFLGITPLLLSIPVQIGIVYAFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYKQLKNENIVESIKNETI"
     gene            complement(5561..6742)
                     /locus_tag="JAM15_19520"
     CDS             complement(5561..6742)
                     /locus_tag="JAM15_19520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAT6800402.1"
                     /translation="MKTPRNINSTVVFIIFCLIITFLLSVILTTITSFNEYNVLSKAL
                     GASYEYNPKSTESILKSLKNSSDKDFKTGNEILSKHGYSKSTFWSKNFFYFLVISFGI
                     ISTMATVVYIIKHRTNKQKLSRINNLTQYLEEVNLGKESVLLRCEDEFSHLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TNQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     ESSPSVEFEIDINWTLEALLNILKNCSEHIEDGGYIVAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTLHAENCHNGGARFIIKFY
                     T"
     gene            complement(6742..7404)
                     /locus_tag="JAM15_19525"
     CDS             complement(6742..7404)
                     /locus_tag="JAM15_19525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAT6800403.1"
                     /translation="MAKILLLEDDDTITFGIKTSLEKKNHTVCCYNTIAEAKKNFDKT
                     IDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRTHSNTNNTITCGNISLNKVEVKAYLDNVEVLLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DS"
     gene            complement(7549..>8087)
                     /locus_tag="JAM15_19530"
     CDS             complement(7549..>8087)
                     /locus_tag="JAM15_19530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAT6800404.1"
                     /translation="TMNELAKEVEYTKRTIYKYFSCKEDLFFAVVLRGYKRLWDNVKI
                     ESAKGKTGFEKIKLSYFAFHKFYSVEPSLLCLMGMIGIVNSEKSDTDMLFKEKFFSFN
                     KFMFDEIQGMFEIGKNDRSIRHDIEIPTLMYSSIFTLTGFFNLLSVTGKSYLNNFNID
                     EEKFIETTLALLIDSIKA"
BASE COUNT         3008 a         1007 c         1281 g         2791 t
ORIGIN      
        1 aaaggaggac ataatgatac taatagttat attgagtata ttcatcatag cctcaatcaa
       61 cataattata ttaggtaaag aaaatataag agatatagtt atccctttaa ctctatttat
      121 tgtaagtgat tttttatttt tgtgtggaaa tataatatgt aggggaggag taatgctact
      181 atttataggt ttatttgcaa taccattgat gctaattgca tttatatgga tttgtgtaca
      241 tatgattaag ctttactata aaaaagattt aaataaaaga aaaatgattg gatgtatatt
      301 tagtatcttt ataagtatag gtactatatt tattcctagt ccaagtgaaa gttttagatt
      361 taaactttat gaaaaagatt atagtgtagt agctaaagct attttgaaag tttatgatga
      421 aaaaaagtta agctctgaat ctgtctttta tattcaatct gataaaaatg aattggagaa
      481 gatattttct aaagaagtaa taaaaaaaat gaaaaaacta aacagaaatt tagatgtagt
      541 taaaatttct gggaatagaa atttagtcta ttttttcttt ggagctgaat tacaatctat
      601 tgatggtatt gtgattttta aagatttaaa acatgttaaa ccaaagttag attttataaa
      661 tagaagtatt caagctccta gattggagta tattacaaat aatgtatatt attttaaagg
      721 tgaactataa acttatgtag aggagatggt ataaagtatg aaaagaaaaa ataattttat
      781 ttggatagtt attcttctag ttgttgtagc tatgggagta tattatgtag gaagaaagca
      841 taacaacaca aaacaaaaac atgataagaa tcatataaac tctgaattaa ataaatccaa
      901 agttgaaaac aatgataaaa acaaaaaaga aaaaattaat atggttgact atagtgattg
      961 ttttgaaggt attagtggag gagctatttt ttataatact aaaaataaag aatataatat
     1021 atataacaaa gaattaattg aaacaagaag gtcaccatgt tctactttta aaatagtttc
     1081 aactttaatt ggtttagaaa aaggggtaat aaactcaaaa gaatcagtta tgggatatga
     1141 tggtacagag tatccaaata aaaattggaa taaaaatctt agtttagaag aggcatttaa
     1201 ggagtcttgt gtttggtact acaaaaaatt gatagataaa gttgatgcta aatctgtcca
     1261 aaacatttta gatgatttaa agtatgggaa ttgcgatatt agcgaatggg aaggagattt
     1321 aaaaaatgga aagggacatt taaatggatt ttggttagaa tcttcattac aaatatctcc
     1381 aaaagaacaa gtgcaaacaa tggcaaaaat atttgaggga gatacaaact ttaaaaaaga
     1441 gcatattaat attttaagag atattatgaa aatagatgtg aatgataaaa acataaatgt
     1501 atatggaaaa actggaacag gatttgatga aaaaaataaa cgtgtggatg catggtttgt
     1561 tggtatgcta gagcgtgaag gtgacaccta ttattttgct attaaatcag atgattccaa
     1621 taaagaaatt acagggccaa aggtaaagga aattgcaatt aatataatta agaaatatta
     1681 tagtgtaagg gaataaactt aattttattt gtaaatatta tttacctata gtctgtaata
     1741 tttattaaat aattttacta aattgagtct atatagagca aaactccttt agtacataaa
     1801 atacttgcta ttgattatta aattgaatac ctatagattt aaagttaata ccttttaaag
     1861 actatgtaat atattaaaag tataaataaa atatattgca tagtttttgt tttatattat
     1921 aattttaaat aatgtgcaaa aactaaacaa tatttttaat agtaatttat atttgtattc
     1981 atgtcactat aatgtcattt taggttgcta aaatttaacc ataaaggaga tgattgtata
     2041 tggaaatatt aaaatgtgaa aatctcacaa aaatatatgg ttcaaatcaa accagagtga
     2101 cagcccttaa taatgtaaat ttatcagttc aaaaaggtga ttttgtatcc attgtaggag
     2161 catctggttc tggcaaatct acattgttac atctgcttgg gggagtagat agacctacat
     2221 ctggaaagat ttatgttgaa gatacagaaa tatcaagttt aaaggaagaa gctcttgcag
     2281 tttttagacg tagaaaagta ggtcttattt atcaatttta taatcttata cctacccttg
     2341 atgttagaaa aaatatatta ttacccatgt tacttgataa aagaaaggta gatgaggata
     2401 gattctctga gattgtatct atattgggat tatctgatag attaaaccat cttccaagtc
     2461 aactttcagg tggacaacaa caaagggtat ctatagctag aagtttaatc tatagaccag
     2521 ctattttatt agcagatgag ccaactggta atcttgatag aaaaaattca gaagaaattg
     2581 tagacttgtt aaacttatca aataaacgat ttaatcagac aatacttctt attactcatg
     2641 atgagaaaat agcactagag gcaaatcgta ttgtaactat ggaagatgga gtgattgtct
     2701 ctgaaaaggt ggtgaagaaa tgaatattct tcaagaatac accttagact ttgtacgacg
     2761 caataaacgt agtagtatag ctataatgtt agctatatta cttactacaa ccatgatgtc
     2821 ttctttgtgt ggactgttgt ataccatgtg gacagatttt ataagacttt caattgagaa
     2881 agaaggtaac tggcatggtg aattgtttga ctatacttat ggaagtgact taccattaat
     2941 tgaaaatttt tcttcagttg atgatgtaat ggtaaaagga caatggtatg taggcaaaat
     3001 taatgatgag aaaagagatt atataattta tagaaatgct acatcagagt attggaattc
     3061 tatgccagaa aaggatacta taatagaggg tcgtcgacca aataatgcta atgaaattgc
     3121 attatcaaaa caatattttg agaataatcc aagtgtaaaa attggggata aaattactct
     3181 tccaatagga gatagaatcc taaatggaaa gcctcttgaa cccatagctc aaaaatcgaa
     3241 aggggaaagt tttaaaaaaa tttcagagac tacattgaca atagtaggaa aggtagatgt
     3301 ttccacttca tcagtaatac ctgcatatac agctcttgga tatcttgata gaacaagtat
     3361 aaaacctaat gatagtataa ctgtgtactt gcgatttaaa aatataagag acacatacaa
     3421 ggaacttcca aaacttgcta aatcattggg gtggaagact aatgaatatg gaaaatacaa
     3481 tcttaaatat aatagtaatt atcttttaaa aatgttagtc ttttccccag aacagaaagc
     3541 atctatgagc agtatatcaa aattttcaac tcctattatg tatcttacaa tagcaatttt
     3601 tacagtagct gtgtttgtaa tggtgattta caacgcgttt tcactatctg caaatgctag
     3661 acttactcaa ttagggatat tatctagtgt tggtgcatca ccaaaacaaa ttaaaatgtc
     3721 tgtagtgttt gaaggttttt tgcttacaat tataccattg ccaataggtt tatttttagg
     3781 atggttattg tgtaataggc ttatagttta tattaattca gttaattatc atactgatgt
     3841 tccagaagtg gtatttactt atggtattcc tgcttttctg ccagcagttt tacttacaat
     3901 agtaacagtc tggatttctg cacttatacc agcacgaaaa gtatcaaaga tatctcctat
     3961 agaagcaata cgacaaggag atagtgttaa aatcaaaaag tcgcataaat attcattagg
     4021 aaagatattt ggaatagaag gagaacttgc atcaaacgca ctacgtgctc gtaaaaaatc
     4081 ttatcgtact gcaacaatat ctttaacatt atctttttta ttacttacat gttttttgca
     4141 tataattgca aatcaagaag gagcaaaagc tgtttatgga agtgataatt ataaggacca
     4201 aagagatata gcagtttatt tggaaaatag tgaacctgta gagtctgctt tcattgaaaa
     4261 attagataat acagaaggtg taaaaagttc actatattat caaaaaatgt ctgcttccac
     4321 ttggctgact gaaaaagatg catcaaaaga acttgcgaaa aatggaggat ttaaaagtat
     4381 agtttcatct aaaaaatact ctcctataga acgtgatggc aagtttcgta taatttcaaa
     4441 tataattggg cttgatgata agagttttac agaatattgt aggcaaattt ctgtagaccc
     4501 aaagttattt tatgatacaa aaaatccaac ctcaattgta tataataagg aggaagatat
     4561 taatcgtagt acacgtagaa ataaagtata tatagattat ttaaatcttt caataggaga
     4621 taacattaaa ttaaatgaaa aagtatatga cgaagataaa ggggattata cttacaacat
     4681 gaaagtggga gctattacaa gcacacttcc taaaatagta gatactagtt caaaatatac
     4741 attaatgcaa atagtgccaa tgtctatggt gcaggaaata tctaaaaatt atgatgaagt
     4801 aagtaggtta cgttcaaata ggctgatagg agtatttaaa gtaaataatc gtgaggacat
     4861 tcctagagta agagaaaaat tagagtccat ttataataaa gactatggtt caggagatta
     4921 tagtattgag gatgttttag aaagtgaaaa acaaaaggct agtggaataa agaccatgaa
     4981 tttaatagta ggctttatta caggtttatt ggctatgatt ggattatcaa atgtacttgc
     5041 tacagtgtca ggaaatatta gaagtagacg acaagagttt gctatgttgc gttctgttgg
     5101 attatctcca gaaggcataa aaaagatgct tgttttggaa ggtttgttct taggaattac
     5161 accattacta cttagtattc ctgtgcaaat aggaatagtg tatgcttttc tacgtataaa
     5221 tgaaatatat tttatagagt atttaccatt tgcacctata tctacaataa taggttttac
     5281 tatattgata ctttttattg taatagcatc atatatgaca ggatacaagc agttgaagaa
     5341 tgaaaatata gtagaatcta taaaaaatga aacaatataa acaaaagcta tttgaactta
     5401 tttaaaggtt tcgatttaag actacttaca agtataggga tagttaattt gtttgtttaa
     5461 taaaacctta aatgtaaata gaagtatatt actaaaacaa tagataacat agaatataga
     5521 tatagctgga ttataggtat tttacctata atccagcatt ttatgtgtaa aatttaatta
     5581 tgaatcttgc accaccatta tggcaatttt ctgcatgtag agtaccattt tgacgttcta
     5641 taatagactt tgatagagca agccctatac caatactgtc cttactagca tttttaccac
     5701 gataaaatct attaaaaata tatggaagtt cttcctgagc aaacccctta ccattatctt
     5761 ctatgataat ctcaacatat agaggatttt gactataata agcaactata tatccaccat
     5821 cttctatatg ctcactacaa tttttaagaa tatttaaaag agcttctaaa gtccaattaa
     5881 tatcgatttc aaattctacc gaaggagaag actcgatagt aaatgtctga tgtttttctc
     5941 ttaaagaacc ttctataggc tcaattgcat aagtaagaag agaatgtaca tctataagtt
     6001 tgctttcaaa tattaaagta cttgcatcca attttgataa tgtaagtaaa gatgaaacta
     6061 atctctcaag tcttgagatt tgatttgtaa gtctgttaat ataatctatt tcttcatctg
     6121 gacaattttc tgaaagtaat tgtgccataa gtgacataga agtaattgga gtcttaagtt
     6181 gatgagcaat atctgcaagg ttatctgaaa gagtttgtct ttcttttaaa gcaaattctt
     6241 ttgaacaacg aagttcccca actgttttat atatctcatc ttcaaggtga gaaaattcat
     6301 cttcacatcg taaaagtaca gactcttttc ctaaattcac ttcttctaag tattgagtaa
     6361 gattgtttat tctactcagt ttttgcttat ttgttctatg tttgattata tatacaactg
     6421 tagccattgt tgaaattata ccaaacgata tcactagaaa ataaaaaaag tttttactcc
     6481 aaaatgtact tttagaatat ccatgttttg ataaaatttc atttcctgtt ttaaaatcct
     6541 tatcactaga atttttcagt gattttagta tactttctgt agacttagga ttgtactcat
     6601 atgatgcacc aagagcctta gacagtacat tgtattcatt aaaagaagtt atagttgtta
     6661 gaattacact taataaaaaa gttataatta agcagaatat tataaaaaca actgtactgt
     6721 tgatatttct tggagttttc actagctgtc ctccattcta tatcctatgc ctcttaatgt
     6781 ttttatacaa ggtggatttt ttaatttttc tctaagacgc tttattgtaa cagtaagagt
     6841 gttatcattt acgaaattac catctacatc ccagagcatt tctagtaact ttgtacgagt
     6901 catagctcta tttttatttt ccataagact tagaagaagt ttatattctc ctgctgtcaa
     6961 aagtacttca acattatcta aatatgcttt gacttcaacc ttattcaagc ttatatttcc
     7021 acatgtaata gtattgttag tatttgaatg agttcttcta agaactgcat taattctgga
     7081 ttgaagtact gagagcagaa atggtttaac cacatagtca tctgcaccca tatctaatcc
     7141 acgtataatg tctttttcat catcacggac tgtcaaaaat atcactggag tatcttctat
     7201 acttttaaca tattggcaaa actcgtatcc aataccatca ggtagattta aatcaagcag
     7261 aattaaatca atagttttat caaaattttt tttagcttca gcaatcgtat tataacaaca
     7321 tacagtgtga tttttctttt caagggaagt ttttattcca aatgtaattg tatcatcatc
     7381 ttctaaaaga agtattttag ccatttactt ttagtccttt cagtaattta gttatttcat
     7441 taactaagtt attagtttta tgtttaatat tttttatgtt agagatagaa gttagagata
     7501 gaaaaaatta tcatttaagt atataaactt taatttataa acttaggttt atgctttaat
     7561 tgaatctatt aaaagagcaa gagttgtttc aataaatttt tcctcatcta tattaaagtt
     7621 gttcaggtat gactttcctg ttacagatag taaattaaaa aatcctgtaa gtgtaaatat
     7681 tgatgaatac atgagagtag gtatttcaat atcatgccta atacttctat cattttttcc
     7741 aatttcaaac attccttgta tttcatcaaa cataaattta ttaaaagaaa aaaacttttc
     7801 tttaaacagc atatcagtat ccgatttttc agagtttaca ataccaatca ttcccataag
     7861 gcataataga gaaggttcta cagagtaaaa tttatgaaaa gcaaagtatg aaagttttat
     7921 tttttcaaac cctgttttgc cttttgcact ttctatttta acattatccc aaagtctttt
     7981 atatcctctt aagacaacag caaagaataa atcttcttta catgaaaaat acttatatat
     8041 ggtgcgttta gtatattcaa cttcctttgc caactcattc atagttg
//
LOCUS       DACTZW010000217         5979 bp    DNA     linear   BCT 10-DEC-2020
DEFINITION  TPA_asm: Clostridioides difficile isolate Symptomatic Infection 19
            SAMN04153076-rid8933093.guided.144, whole genome shotgun sequence.
ACCESSION   DACTZW010000217 DACTZW010000000
VERSION     DACTZW010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN04153076
            Sequence Read Archive: SRR2751311
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-JAN-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 25-JAN-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000669731.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000669731.1
            Genome Coverage       :: 69x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/25/2020 19:00:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 4.10
            Genes (total)                     :: 3,915
            CDSs (total)                      :: 3,835
            Genes (coding)                    :: 3,762
            CDSs (with protein)               :: 3,762
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 2, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6 (5S)
            partial rRNAs                     :: 2, 5 (16S, 23S)
            tRNAs                             :: 63
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 23 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 27 of 73
            Pseudo Genes (multiple problems)  :: 9 of 73
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5979
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN04153076-rid8933093.guided.144"
                     /isolate="Symptomatic Infection 19"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="USA: NJ"
                     /collection_date="09-Sep-2004"
     gene            73..462
                     /locus_tag="JAM15_19535"
     CDS             73..462
                     /locus_tag="JAM15_19535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HAT6800405.1"
                     /translation="MKINKLPHAELKLMKYIWGVDDVLASRDIIETMKLKYDWKKSTT
                     LTFLKNLVDKGFLTTDKVDRCTHYTIAIKEKDYLKVETKSFFSFMHNNSFKSFISALH
                     DDEVLDSKSLDKLEEYFKNLKEEDIDD"
     gene            784..1293
                     /gene="vanZ1"
                     /locus_tag="JAM15_19540"
     CDS             784..1293
                     /gene="vanZ1"
                     /locus_tag="JAM15_19540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ1"
                     /protein_id="HAT6800406.1"
                     /translation="MKSRKHNITKGLFIVYIIVLTWIILFKLQFDISSLETMNLRSIN
                     LVPFAGSLIINNRVDISEIILNVVIFVPFGIYVCMLKEKWSFIKKVIPIFITSLAFET
                     LQYIFALGASDITDLIGNTLGGIIGIAVFMLLSKIFKNNAIKIINVLALIVTIIVVLF
                     LGLVIFANL"
     gene            complement(1395..1589)
                     /locus_tag="JAM15_19545"
     CDS             complement(1395..1589)
                     /locus_tag="JAM15_19545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase"
                     /protein_id="HAT6800407.1"
                     /translation="MSVIVMCSRCGKEIDKYRNKYITYYEKNTNAEIKVCINCALDLL
                     EKTRENQELNIQEFQDTIIL"
     gene            complement(2109..2501)
                     /locus_tag="JAM15_19550"
     CDS             complement(2109..2501)
                     /locus_tag="JAM15_19550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAT6800408.1"
                     /translation="MAALKSFEKPLTPEEEIEYLTKFKIENDKSAKDTLIERNMRLVA
                     YIAKKYNNSTEDQDDLISIGTIGLIKAIETYNIDKGTRLATYASRCIENEILMNIRSN
                     KKNKTQVSLQDPIGTDKEGNEINATFYM"
     gene            3069..3431
                     /locus_tag="JAM15_19555"
     CDS             3069..3431
                     /locus_tag="JAM15_19555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800409.1"
                     /translation="MKIRKSGFISIECIISIAILYVAVYLVSTSLYNCYSFISRNISD
                     REMLSTAKKYIEDEKYRIQNSKYELIEDKIEKNYINGYEINSRIEQILDYYQCYEINI
                     EIKNEFKKLRFNSYVTRK"
     gene            3415..4131
                     /locus_tag="JAM15_19560"
     CDS             3415..4131
                     /locus_tag="JAM15_19560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800410.1"
                     /translation="MLLENKGSILIITLIIFSIISTVCIMCIGLIYTHNNMFELGYKD
                     IQLKEISLSGIEISVSNVLSCVEEAIDVSNNEDEFREYFLGNNMIECIKKIKDTSYSS
                     LEELSLKVENNTIYDRGDFFEFDIESNVREKEFLKAIKVRVKIKNPWIGIDIEDYMDK
                     SNNNKIDDKTFNNYKASENNEILNQFKNESENIRNQEVVEFTEEDEEYEEELKQNIIE
                     NIKKNFDEKKLVQVYKYRGV"
     gene            4151..4570
                     /locus_tag="JAM15_19565"
     CDS             4151..4570
                     /locus_tag="JAM15_19565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800411.1"
                     /translation="MTVIELIVSISIILLIVTLSFPKDNLENHKINLFARQLCSDIRY
                     VRRINMFSNYNTYIYYINQGKYEGYVLRKDGKNIKSIMLPKNAKIARSIEIIKFKSDG
                     SPQKASTIEIYNNRLRKTITITPVSGRVLLKEGKYET"
     gene            4560..5084
                     /locus_tag="JAM15_19570"
     CDS             4560..5084
                     /locus_tag="JAM15_19570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAT6800412.1"
                     /translation="MKHKYGYLLLESVVSLSSMVIIILVLYSIFLSTINLKLKVEDKI
                     ELQQQSLEIIKSMEGIISNSMGIMNVSNYEETFKKTTSIKCRYVDENNNEESISNKEI
                     ILNERRNKLFVNSLNGESSQAGGYEIGDYVDEMYVLITNNGQYVNIKLKLSKRSQKYE
                     TDFKIKVWNFSESI"
     gene            5396..5953
                     /gene="efp"
                     /locus_tag="JAM15_19575"
     CDS             5396..5953
                     /gene="efp"
                     /locus_tag="JAM15_19575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007287307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HAT6800413.1"
                     /translation="MVSAGDFRKGVTFEKDGQPCLVVDFQHVKPGKGAAFVRTKYKNL
                     KTGAIREESFNPSEKFPKAVIDTRQMQYLYNDGELYYFMDQENFEQIPLNYEQVEDAI
                     KFLKENEVATIRFYQGQPFQVEAPNFAELEVTDTEPGIKGDTASNVTKAATVETGAVV
                     QVPLFINTGDKVKIDTRTGEYLSRV"
BASE COUNT         2471 a          535 c          914 g         2059 t
ORIGIN      
        1 caatctaatt gattacatac acttattgtt ataaagttta gttatacata aattggtaag
       61 aggtgtaaac taatgaagat taataaatta ccacatgcgg aactaaaact aatgaagtat
      121 atttggggag tagatgatgt attagcctca agagatatca tagaaacaat gaagttgaaa
      181 tacgattgga aaaagagcac aacattgaca tttttaaaaa atttagtaga taagggcttt
      241 ttaactactg ataaggtaga tagatgtacg cattatacta tagctataaa agagaaagat
      301 tatttaaaag ttgagacaaa gagtttcttt agttttatgc ataacaattc atttaagagt
      361 tttatttcag cattacatga tgatgaagtt ttagatagta aaagcttgga caaattagaa
      421 gaatacttta aaaatttgaa agaagaagat attgatgact aataaagcta tcagtatctt
      481 tttagtttga gacaattgag agtagcgttt tgatttaatg ttagtgttat gtgatggtag
      541 aaaattatat aaagaaaagt gattatttcc ttagtatttg atagtaaaaa atatagaaaa
      601 taataccaac taaattttaa agaaagatat gaaatactac aatagcttaa atcatgcaaa
      661 tatgataaag aaattgaaat tataaaagga atataatttt agaagaaata gttgacagat
      721 aaattacctt actatattat tgtattaata aaataataca ataatatagt aaggaggtaa
      781 taaatgaaat ctagaaaaca taatattaca aaaggattat ttatagttta cataattgtt
      841 ttaacatgga taatactatt caagttgcaa tttgatattt catcccttga aaccatgaat
      901 cttagaagca taaacttagt accttttgct gggtcactta taattaataa tagagtagat
      961 atatcagaga ttatattaaa tgtggttata tttgtaccat ttgggatata tgtgtgtatg
     1021 ctaaaagaaa aatggagctt tataaaaaaa gttataccta tttttataac tagtttagca
     1081 tttgaaacac ttcaatatat atttgcacta ggtgcaagtg atataacgga tttgatagga
     1141 aatacactag gaggaatcat aggaatagct gtttttatgc tattatcgaa aatatttaag
     1201 aataatgcca taaaaattat caatgtattg gcattgattg tgacaattat tgttgtatta
     1261 tttttaggat tagttatttt tgcaaactta tagaaataag tatatatgtt tagcttaaaa
     1321 taaaatgtaa gatacaatta catataaaat tatttacaca taaaaagcac ctatacaggt
     1381 gctttcctaa attattaaag aattattgta tcttgaaact cttgtatgtt caattcttga
     1441 ttttctcttg ttttttctaa taaatctaac gcacaattta tacaaacttt aatttctgca
     1501 ttggtatttt tctcataata agttatatat ttatttctat atttatctat ttcttttcca
     1561 caacgactac acattacaat tacgctcata tcttagttcc tccatctcta attattctta
     1621 atatattcaa tagtatcact tttctgaaaa taatgattgt taaaactgta tcaaatttag
     1681 atttactttt tattataatg cattttaata aaaaaataaa ggttatgagt aaaatattta
     1741 tagaaaaaag tatattattg aatagattat aaaattttat tattttttat cagtcttaaa
     1801 tacacattaa tatctataaa atgacaaaat aaaaaatact atttaaatag atattaaaaa
     1861 agtgatacca agtatttgtt tgctatatga ataacaattt atttaggagc tttactttga
     1921 cactgtataa taataaagta attgctaaaa acgttggatg atttggatgt atttttagaa
     1981 attagaaaaa tatatactta ctgactaatg ataatcttat atgtatttta gtttgagtga
     2041 tttaagaaaa gtgttttgaa aagggattat tttatagagt aaataaatat atatatatgg
     2101 tagaaaaatt acatataaaa agtagcgttt atttcattac cttctttatc tgttccgatg
     2161 gggtcttgta gagatacttg agttttattt tttttgttag atctaatatt cattaaaatc
     2221 tcattttcaa tacatctaga agcatatgtt gctaatcgag ttcctttatc tatgttataa
     2281 gtttctatag ctttaattaa tcctattgta cctatggata ttaaatcatc ctgatcttcc
     2341 gttgaattat tatatttctt tgctatataa gctactaatc tcatgtttct ttcaattaat
     2401 gtatcttttg cacttttatc gttttctatt ttaaatttag ttaaatactc aatctcttct
     2461 tcaggggtta agggtttttc aaaagattta agagctgcca ataggtcacc cccttttcaa
     2521 cggtcacttt aaattatatg aaggagactt atccaagttg actgttatct aataaaataa
     2581 tatgcatatt tttagaattt aaaacatata tttgcaaact tttgaatgga atatgacata
     2641 aagagtggga atttaaattt aagtttttgt tgtatatata tgaaacaagg cgaagaaatt
     2701 attgatttat aaagtataaa ttggaattga ggtgtcaata aatataaaag gaaatagtat
     2761 ttatatatgt tttggtgttg aggtaaaaga ttaatgcaaa gcattagagt ctataaaaat
     2821 atgaatatag gaggtgtaat tttacaatac ttaaaaaagt aaatgtaatt aattgtttgt
     2881 ataaagttga ttacaagcaa aaagtatcag tcatagttaa ttctgttaag gatgaaggtg
     2941 gtgtgttaat ttatatatgt atgggaagaa attttgatta caatgaaaaa acttacaaaa
     3001 gatatttatg aaaaaactta tagttaaatg tttatatata aaatattatt taggggttgt
     3061 ttttattatt gaaaataaga aagagtggtt ttatatcaat cgaatgtata ataagtattg
     3121 ctatattata tgtggctgtt tatttagttt ctacatcatt gtataattgt tatagtttta
     3181 tcagtagaaa tatatctgac agagaaatgt taagtacagc aaaaaaatat atagaagatg
     3241 agaagtatag aatacaaaat agtaagtatg agttaattga agataagata gaaaaaaatt
     3301 acataaatgg atatgaaatt aacagtagaa tagagcaaat tttagattat tatcaatgct
     3361 atgaaataaa tatagagata aaaaatgaat ttaaaaaact gaggtttaat agctatgtta
     3421 ctagaaaata aaggctctat attaataata acattgataa tattttctat tataagtact
     3481 gtgtgcatta tgtgtatagg tttaatttat acacataata atatgtttga gttaggatac
     3541 aaggacattc aactaaaaga aatttcttta agtggaatag aaatatcagt aagtaatgta
     3601 ctttcttgtg ttgaggaagc tattgatgta tctaataatg aagacgaatt tagagaatat
     3661 ttcttaggaa ataatatgat tgaatgtata aaaaaaataa aagatacatc ttatagtagt
     3721 ttagaagaac tttctttaaa agtagaaaat aatactattt atgacagagg agattttttt
     3781 gaatttgata tagaaagtaa tgttagagaa aaagaatttt taaaagcaat aaaagtaaga
     3841 gtgaaaatca aaaatccatg gataggaatt gacattgaag attatatgga taaatctaat
     3901 aacaataaaa ttgatgacaa aacattcaat aattataaag catctgaaaa taatgaaatt
     3961 ctaaatcaat ttaaaaatga aagtgaaaat ataaggaatc aagaggttgt tgaatttaca
     4021 gaagaagatg aagaatatga agaagaactt aaacaaaaca taattgaaaa tataaagaag
     4081 aattttgatg aaaaaaaact agtacaggta tataagtata ggggtgtata actttgaaaa
     4141 aagaaggaat gtgactgtaa tagaattaat agtatctatc agtataatac tcttgatagt
     4201 tacattatct tttccaaagg ataatcttga aaatcataaa ataaatttat ttgcacgtca
     4261 actttgttca gatataaggt atgttaggcg aattaatatg tttagcaact acaatacata
     4321 tatatattat ataaatcaag gtaaatacga aggttatgta ttgagaaaag atggtaaaaa
     4381 cattaaatca ataatgctac ctaaaaatgc aaaaatagct agaagtattg aaataataaa
     4441 gtttaaatct gatgggtcgc ctcaaaaggc gtctacaata gaaatatata ataatagatt
     4501 aagaaaaact ataacaataa cacctgtaag tggaagagta cttctgaaag agggaaaata
     4561 tgaaacataa atatggttac ttgcttttgg aaagtgtagt atcattgtct tcaatggtga
     4621 taattatact agttttatat tctatatttt tgtctacaat aaacttaaag ttaaaagtag
     4681 aagataagat agaactacaa caacaaagtc ttgaaatcat aaaatctatg gaaggaatta
     4741 ttagcaattc tatgggaata atgaatgtat ctaattatga agaaacattt aaaaagacaa
     4801 cgtctataaa atgtagatat gtagatgaaa ataataatga agaaagcata agtaataaag
     4861 aaattatatt gaatgaaaga cgaaataagt tatttgtaaa ttctttaaat ggcgaaagta
     4921 gtcaagcagg tggttatgaa attggagatt atgtagatga gatgtatgta ttaattacta
     4981 ataatggtca atatgttaat attaaattga aattatcaaa acgtagtcaa aaatatgaga
     5041 ctgatttcaa aataaaagta tggaatttta gtgaaagtat ataaaaatac ataaatttaa
     5101 gataaagaaa tgacatcaat aagtcatata aaatataatt attgagaact atataactaa
     5161 ataatatcaa tatgtaaagt gtatagatta agaatataga ggataataat aaaaatatag
     5221 aataagtaat ttgccaaata cttgtttata ttgtataact tatgatatta tgatattagt
     5281 aaaaatttgt aatcctgact tgacagaatt caagtaagag atataatttt aaaggcatag
     5341 taatgtaaaa tttactaaaa aataagaaat ttattttaat atggaggaac aaaaaatggt
     5401 atcagcaggt gattttagaa aaggtgttac atttgaaaaa gatggacaac catgtttagt
     5461 agttgatttt caacacgtta agccaggtaa aggagctgct ttcgttagaa ctaaatacaa
     5521 aaacttaaaa acaggagcta taagagaaga aagtttcaat ccaagtgaaa aattccctaa
     5581 ggctgttata gatacaagac aaatgcaata tctatacaat gatggtgagt tatattattt
     5641 tatggatcaa gaaaattttg aacaaatacc attaaactat gagcaagttg aagatgcaat
     5701 taagttctta aaagaaaatg aagttgctac aataagattt taccaaggac aaccattcca
     5761 agtggaagcg ccaaactttg cagagctaga agttacagat acagagccag gtataaaagg
     5821 tgatacagca agtaatgtaa ctaaagcagc tacagttgaa actggagcag ttgttcaagt
     5881 tccattattt ataaatactg gagataaagt aaagatagat actagaacag gtgaatattt
     5941 atcaagagta taaaaattta tgtatataaa agcttatat
//
